# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Actin PF00022.14 EKG08841.1 - 2.5e-21 75.5 0.0 2.5e-21 75.5 0.0 1.0 1 0 0 1 1 1 1 Actin Methyltransf_29 PF03141.11 EKG08841.1 - 0.011 14.1 0.0 0.011 14.1 0.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribul_P_3_epim PF00834.14 EKG08843.1 - 2.5e-18 65.9 0.0 2.6e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PPDK_N PF01326.14 EKG08845.1 - 2.3e-07 30.1 1.3 1.5e-06 27.5 0.9 1.9 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Rho_N PF07498.7 EKG08847.1 - 0.039 13.7 0.6 0.062 13.0 0.1 1.6 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain CENP-H PF05837.7 EKG08847.1 - 0.07 13.3 1.6 0.076 13.1 1.1 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF2630 PF10944.3 EKG08847.1 - 0.073 13.1 3.0 0.1 12.7 2.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2630) Atg14 PF10186.4 EKG08847.1 - 0.5 9.2 4.4 0.5 9.2 3.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cation_ATPase_C PF00689.16 EKG08850.1 - 2.6e-14 53.1 0.0 2.8e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Bac_Ubq_Cox PF01654.12 EKG08852.1 - 6.4e-24 84.1 0.5 6.9e-24 84.0 0.4 1.0 1 0 0 1 1 1 1 Bacterial Cytochrome Ubiquinol Oxidase Alpha-amylase PF00128.19 EKG08858.1 - 2.6e-16 59.9 0.0 2.8e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Lsr2 PF11774.3 EKG08861.1 - 0.093 12.6 0.5 0.12 12.3 0.4 1.2 1 0 0 1 1 1 0 Lsr2 Ribosomal_S7 PF00177.16 EKG08864.1 - 1.5e-09 37.5 0.4 1.6e-09 37.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CENP-B_N PF04218.8 EKG08864.1 - 0.0092 15.3 0.2 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Complex1_49kDa PF00346.14 EKG08867.1 - 4.6e-09 35.6 0.1 6e-09 35.2 0.1 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NAD_binding_7 PF13241.1 EKG08869.1 - 2.4e-23 82.3 0.0 2.7e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 Putative NAD(P)-binding ThiF PF00899.16 EKG08869.1 - 0.006 16.4 0.0 0.007 16.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family TrkA_N PF02254.13 EKG08869.1 - 0.012 15.6 0.1 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain TruB-C_2 PF09157.6 EKG08869.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Pseudouridine synthase II TruB, C-terminal ACPS PF01648.15 EKG08871.1 - 0.018 14.8 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Trypsin PF00089.21 EKG08874.1 - 0.0024 17.4 0.2 0.0089 15.6 0.2 1.7 1 1 0 1 1 1 1 Trypsin CHAP PF05257.11 EKG08874.1 - 0.013 15.1 0.3 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 CHAP domain D-aminoacyl_C PF07908.7 EKG08874.1 - 0.11 11.8 0.7 0.26 10.6 0.2 1.8 2 1 0 2 2 2 0 D-aminoacylase, C-terminal region SpoIIE PF07228.7 EKG08875.1 - 5.1e-18 65.4 0.0 5.5e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) AMP-binding PF00501.23 EKG08876.1 - 0.0013 17.1 0.0 0.0015 17.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Methyltransf_19 PF04672.7 EKG08878.1 - 2.8e-23 82.5 0.0 3e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl methyltransferase 2-oxoacid_dh PF00198.18 EKG08880.1 - 1.1e-31 109.8 0.0 1.2e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) RIC1 PF07064.8 EKG08882.1 - 8.2e-20 71.3 0.0 9e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 RIC1 Asp PF00026.18 EKG08884.1 - 2.9e-23 82.5 0.9 3.5e-23 82.3 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKG08884.1 - 2.2e-06 27.7 0.0 7.1e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Retrotrans_gag PF03732.12 EKG08886.1 - 9.6e-18 64.0 1.4 9.7e-18 64.0 0.1 1.5 2 0 0 2 2 2 1 Retrotransposon gag protein Exo_endo_phos_2 PF14529.1 EKG08887.1 - 7.3e-06 25.5 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3505 PF12013.3 EKG08890.1 - 5.3e-17 62.0 0.3 5.8e-17 61.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) HCV_NS5a_1b PF08301.8 EKG08890.1 - 0.049 13.9 0.0 0.062 13.6 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b zf-H2C2_5 PF13909.1 EKG08890.1 - 0.087 13.0 1.8 0.13 12.5 1.3 1.3 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EKG08890.1 - 0.55 10.6 3.0 0.83 10.1 2.1 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type F-box PF00646.28 EKG08892.1 - 0.038 13.6 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 F-box domain MarR PF01047.17 EKG08894.1 - 3.5e-07 29.8 0.1 5.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 MarR family MarR_2 PF12802.2 EKG08894.1 - 2.8e-06 26.8 0.6 1.2e-05 24.8 0.1 2.1 2 1 0 2 2 2 1 MarR family HTH_27 PF13463.1 EKG08894.1 - 4.3e-06 26.9 0.8 1.4e-05 25.3 0.4 1.8 2 0 0 2 2 2 1 Winged helix DNA-binding domain Chromo PF00385.19 EKG08895.1 - 4.5e-09 35.8 1.0 7.6e-09 35.1 0.7 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dimer_Tnp_hAT PF05699.9 EKG08897.1 - 1.2e-17 63.2 0.0 1.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DNA_alkylation PF08713.6 EKG08897.1 - 0.051 13.0 0.5 0.063 12.7 0.3 1.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme DUF4440 PF14534.1 EKG08897.1 - 0.076 13.2 0.1 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) FoP_duplication PF13865.1 EKG08897.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 HTH_Tnp_Tc5 PF03221.11 EKG08898.1 - 1e-10 41.2 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG08898.1 - 2.6e-05 23.6 0.2 5e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain RVT_2 PF07727.9 EKG08900.1 - 8.3e-32 110.0 0.0 9e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb2_6 PF00562.23 EKG08905.1 - 3.2e-28 98.5 0.0 3.7e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Aa_trans PF01490.13 EKG08906.1 - 0.00011 20.7 2.1 0.00012 20.6 1.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Retrotrans_gag PF03732.12 EKG08907.1 - 5.4e-17 61.6 0.1 6.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein UBN2 PF14223.1 EKG08907.1 - 0.039 13.7 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Imm43 PF15602.1 EKG08907.1 - 0.041 13.8 0.2 0.091 12.7 0.1 1.5 1 1 1 2 2 2 0 Immunity protein 43 VWA_CoxE PF05762.9 EKG08909.1 - 5.5e-14 51.8 0.0 6.2e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.1 EKG08909.1 - 0.002 18.2 0.0 0.0038 17.3 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain HTH_Tnp_Tc5 PF03221.11 EKG08912.1 - 1.2e-08 34.5 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG08912.1 - 0.0061 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Amidohydro_5 PF13594.1 EKG08914.1 - 1.7e-10 40.5 0.1 3.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG08914.1 - 5.7e-10 39.3 0.0 6.9e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG08914.1 - 7.3e-08 32.7 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Dimer_Tnp_hAT PF05699.9 EKG08917.1 - 1.1e-17 63.4 0.3 1.6e-17 62.9 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HTH_40 PF14493.1 EKG08918.1 - 0.0073 16.4 0.1 0.012 15.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain NADHdh PF00146.16 EKG08919.1 - 2.6e-81 273.0 7.0 2.9e-81 272.9 4.9 1.0 1 0 0 1 1 1 1 NADH dehydrogenase DUF788 PF05620.6 EKG08919.1 - 0.086 12.6 3.2 0.13 12.0 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Retrotrans_gag PF03732.12 EKG08920.1 - 3.8e-19 68.5 0.5 6e-19 67.9 0.1 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein rve PF00665.21 EKG08923.1 - 1.4e-13 51.0 0.5 2.7e-13 50.0 0.2 1.6 1 1 1 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EKG08923.1 - 0.00027 20.5 0.0 0.00052 19.6 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain IFT57 PF10498.4 EKG08923.1 - 0.017 13.9 0.2 0.038 12.7 0.2 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 rve_3 PF13683.1 EKG08923.1 - 0.018 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain TraF PF13728.1 EKG08923.1 - 0.05 13.0 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein RVT_2 PF07727.9 EKG08924.1 - 1.2e-28 99.7 0.0 1.4e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_1 PF03184.14 EKG08926.1 - 1.3e-43 148.6 0.0 3.3e-43 147.3 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 EKG08926.1 - 9.9e-09 35.0 0.0 1.4e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EKG08926.1 - 2.8e-08 33.4 0.0 2.8e-08 33.4 0.0 2.6 4 0 0 4 4 4 1 Tc5 transposase DNA-binding domain rve PF00665.21 EKG08926.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Dimer_Tnp_hAT PF05699.9 EKG08928.1 - 8.6e-19 66.9 0.0 1.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.21 EKG08929.1 - 0.0031 17.6 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain ASD1 PF08688.5 EKG08929.1 - 0.08 12.7 0.1 0.2 11.4 0.0 1.7 1 1 1 2 2 2 0 Apx/Shroom domain ASD1 TGFb_propeptide PF00688.13 EKG08930.1 - 0.0034 16.6 1.8 0.0052 16.1 1.3 1.3 1 0 0 1 1 1 1 TGF-beta propeptide PPI_Ypi1 PF07491.6 EKG08930.1 - 3.2 7.4 6.4 10 5.8 4.5 2.0 1 1 0 1 1 1 0 Protein phosphatase inhibitor HTH_40 PF14493.1 EKG08931.1 - 0.035 14.3 0.2 0.092 12.9 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DASH_Dad3 PF08656.5 EKG08931.1 - 0.22 11.2 1.3 3.4 7.4 0.9 2.3 1 1 0 1 1 1 0 DASH complex subunit Dad3 TAF8_C PF10406.4 EKG08931.1 - 0.46 10.5 3.4 17 5.5 0.1 3.0 3 0 0 3 3 3 0 Transcription factor TFIID complex subunit 8 C-term Oxidored_q1 PF00361.15 EKG08934.1 - 2e-38 132.2 7.5 2.6e-38 131.8 5.2 1.2 1 0 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains gag_pre-integrs PF13976.1 EKG08937.1 - 0.02 14.5 0.1 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 GAG-pre-integrase domain TT_ORF2 PF02957.10 EKG08937.1 - 0.17 12.5 2.2 0.38 11.4 0.4 2.0 2 0 0 2 2 2 0 TT viral ORF2 DDE_1 PF03184.14 EKG08938.1 - 3.4e-06 26.3 0.1 1.8e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EKG08938.1 - 5.7e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Dimer_Tnp_hAT PF05699.9 EKG08940.1 - 2.8e-14 52.5 0.1 4.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RVT_2 PF07727.9 EKG08941.1 - 0.00062 18.7 0.0 0.0077 15.2 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1529 PF07485.6 EKG08941.1 - 0.019 14.6 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) RNase_H PF00075.19 EKG08941.1 - 0.034 14.4 0.1 0.058 13.7 0.1 1.3 1 0 0 1 1 1 0 RNase H Utp8 PF10395.4 EKG08941.1 - 0.095 10.9 0.1 0.15 10.2 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Exo_endo_phos_2 PF14529.1 EKG08942.1 - 1.2e-17 63.6 0.0 1.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EKG08942.1 - 5.5e-07 29.7 0.0 6.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNA_pol_Rpb1_R PF05001.8 EKG08942.1 - 1.8 8.9 4.2 0.44 10.7 0.3 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat RNase_H PF00075.19 EKG08944.1 - 3e-12 47.0 0.0 4.8e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG08944.1 - 0.0014 18.3 0.0 0.0048 16.6 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like Peptidase_S48 PF03574.10 EKG08944.1 - 0.028 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S48 DUF1590 PF07629.6 EKG08944.1 - 0.12 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1590) DUF4219 PF13961.1 EKG08946.1 - 1.1e-06 27.8 0.1 1.1e-06 27.8 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EKG08946.1 - 0.0078 15.7 0.1 0.016 14.7 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 EKG08947.1 - 0.047 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 GAG-pre-integrase domain RNase_H PF00075.19 EKG08948.1 - 2.1e-16 60.4 0.0 5e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EKG08948.1 - 0.03 14.6 1.9 0.092 13.0 0.3 2.2 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase DUF4413 PF14372.1 EKG08950.1 - 0.0066 16.4 0.2 0.0099 15.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Fic PF02661.13 EKG08950.1 - 0.11 13.2 0.1 1.8 9.2 0.0 2.1 2 0 0 2 2 2 0 Fic/DOC family RVT_2 PF07727.9 EKG08952.1 - 5.3e-14 51.7 0.0 6.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EKG08953.1 - 0.026 14.8 0.1 0.051 13.9 0.1 1.4 1 0 0 1 1 1 0 RNase H HTH_Tnp_Tc3_2 PF01498.13 EKG08955.1 - 1.1e-18 67.0 1.0 1.7e-18 66.4 0.7 1.3 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EKG08955.1 - 0.0017 19.1 8.8 0.01 16.6 0.7 2.9 3 1 0 3 3 3 2 Homeodomain-like domain HTH_24 PF13412.1 EKG08955.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1264 PF06884.6 EKG08956.1 - 1.6e-18 66.7 0.0 1.9e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) PIF1 PF05970.9 EKG08957.1 - 3.8e-11 42.5 0.9 1.5e-10 40.5 0.6 1.9 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EKG08957.1 - 6.7e-08 32.3 0.0 3.4e-07 30.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG08957.1 - 7.6e-05 22.3 1.0 0.00015 21.4 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EKG08957.1 - 0.00019 21.5 0.2 0.00067 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EKG08957.1 - 0.086 12.5 0.1 0.22 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG08957.1 - 0.14 12.2 0.5 0.46 10.6 0.0 2.0 3 0 0 3 3 3 0 AAA domain FliD_N PF02465.13 EKG08958.1 - 0.025 14.9 4.3 0.068 13.5 3.0 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Peptidase_M24 PF00557.19 EKG08958.1 - 0.032 13.8 0.1 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 P2_Phage_GpR PF06891.6 EKG08958.1 - 0.069 12.9 2.0 0.26 11.0 0.1 2.3 1 1 1 2 2 2 0 P2 phage tail completion protein R (GpR) Med12-PQL PF12144.3 EKG08958.1 - 0.19 11.0 1.9 0.33 10.3 1.3 1.4 1 1 0 1 1 1 0 Eukaryotic Mediator 12 catenin-binding domain Spc7 PF08317.6 EKG08958.1 - 0.26 9.9 4.7 0.41 9.2 3.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.7 EKG08958.1 - 0.4 11.0 9.7 0.38 11.1 5.5 1.9 1 1 1 2 2 2 0 SlyX DUF4164 PF13747.1 EKG08958.1 - 0.41 10.8 8.8 1 9.5 6.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) IncA PF04156.9 EKG08958.1 - 1.2 8.7 8.4 2.2 7.8 5.8 1.4 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 EKG08958.1 - 1.3 6.2 10.3 1.7 5.8 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med9 PF07544.8 EKG08958.1 - 2.2 8.0 5.6 0.61 9.8 0.2 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 APG6 PF04111.7 EKG08958.1 - 2.4 7.0 7.1 3.9 6.4 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF16 PF01519.11 EKG08958.1 - 2.7 8.2 6.2 8.5 6.6 4.3 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.4 EKG08958.1 - 2.9 7.7 10.1 2.5 7.9 5.6 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ISG65-75 PF11727.3 EKG08958.1 - 3.1 6.7 10.2 0.66 8.9 4.2 1.8 2 0 0 2 2 2 0 Invariant surface glycoprotein Atg14 PF10186.4 EKG08958.1 - 7.5 5.3 8.5 11 4.8 5.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RNase_H PF00075.19 EKG08960.1 - 3.3e-15 56.5 0.1 5.8e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG08960.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.7 1 1 0 1 1 1 0 Reverse transcriptase-like Lactococcin_972 PF09683.5 EKG08960.1 - 0.32 11.3 3.2 0.51 10.7 0.8 2.3 2 0 0 2 2 2 0 Bacteriocin (Lactococcin_972) CASP_C PF08172.7 EKG08961.1 - 2e-05 23.7 4.8 0.00014 21.0 3.4 2.0 1 1 0 1 1 1 1 CASP C terminal CENP-Q PF13094.1 EKG08961.1 - 0.00032 20.7 1.5 0.00051 20.0 1.1 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DivIVA PF05103.8 EKG08961.1 - 0.0017 18.4 5.7 0.0033 17.4 4.0 1.4 1 0 0 1 1 1 1 DivIVA protein Nsp1_C PF05064.8 EKG08961.1 - 0.0081 15.7 1.8 0.055 13.1 0.6 2.3 2 0 0 2 2 2 1 Nsp1-like C-terminal region DUF2968 PF11180.3 EKG08961.1 - 0.014 14.8 4.8 0.024 14.0 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Fmp27_WPPW PF10359.4 EKG08961.1 - 0.016 13.6 0.6 0.023 13.1 0.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mod_r PF07200.8 EKG08961.1 - 0.016 15.0 2.0 0.092 12.6 1.6 1.9 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_DNA_bd PF12329.3 EKG08961.1 - 0.018 14.8 6.5 0.036 13.8 4.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.8 EKG08961.1 - 0.021 13.7 4.3 0.039 12.9 3.0 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Muted PF14942.1 EKG08961.1 - 0.048 13.5 4.1 0.074 12.9 2.3 1.7 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Spc42p PF11544.3 EKG08961.1 - 0.05 13.5 1.9 0.16 11.9 1.3 1.8 1 0 0 1 1 1 0 Spindle pole body component Spc42p PhoU PF01895.14 EKG08961.1 - 0.055 13.9 1.0 0.11 12.9 0.7 1.6 1 0 0 1 1 1 0 PhoU domain IncA PF04156.9 EKG08961.1 - 0.058 12.9 1.6 0.096 12.2 1.1 1.3 1 0 0 1 1 1 0 IncA protein GBP_C PF02841.9 EKG08961.1 - 0.12 11.4 5.5 0.19 10.8 3.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain ADIP PF11559.3 EKG08961.1 - 0.22 11.4 8.4 0.66 9.8 5.8 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EKG08961.1 - 0.28 10.2 3.8 0.4 9.6 2.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF641 PF04859.7 EKG08961.1 - 0.36 10.5 3.9 0.62 9.8 2.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF948 PF06103.6 EKG08961.1 - 2.1 8.2 5.6 8.7 6.2 0.5 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) RVT_2 PF07727.9 EKG08962.1 - 0.00014 20.9 0.0 0.0016 17.4 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1529 PF07485.6 EKG08962.1 - 0.02 14.6 0.1 0.035 13.8 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) RNase_H PF00075.19 EKG08962.1 - 0.036 14.4 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 RNase H Utp8 PF10395.4 EKG08962.1 - 0.15 10.3 0.0 0.24 9.6 0.0 1.2 1 0 0 1 1 1 0 Utp8 family DUF3505 PF12013.3 EKG08964.1 - 3e-30 104.6 2.6 3e-30 104.6 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) F-112 PF09645.5 EKG08964.1 - 0.53 10.1 5.4 0.44 10.4 0.3 2.8 3 0 0 3 3 3 0 F-112 protein HLH PF00010.21 EKG08965.1 - 8.7e-08 31.7 0.6 8.7e-08 31.7 0.4 3.5 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain Mito_fiss_reg PF05308.6 EKG08965.1 - 0.96 8.7 13.7 0.057 12.7 1.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator DDE_1 PF03184.14 EKG08966.1 - 6.3e-27 94.1 0.0 7.6e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RVT_2 PF07727.9 EKG08968.1 - 2.2e-75 252.7 0.0 2.9e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Nop14 PF04147.7 EKG08968.1 - 0.05 11.5 7.6 0.071 11.0 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EKG08968.1 - 0.82 7.6 8.1 1.3 6.9 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3408 PF11888.3 EKG08968.1 - 7.5 6.4 10.5 15 5.5 6.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Vfa1 PF08432.5 EKG08968.1 - 7.6 6.5 11.2 12 5.8 7.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RVT_2 PF07727.9 EKG08969.1 - 2.7e-48 164.1 0.4 4.6e-48 163.3 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EKG08969.1 - 0.06 12.6 0.2 0.24 10.6 0.1 2.0 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) CcdA PF07362.7 EKG08971.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Vps5 PF09325.5 EKG08971.1 - 0.02 14.1 0.2 0.023 13.9 0.2 1.0 1 0 0 1 1 1 0 Vps5 C terminal like UPF0542 PF15086.1 EKG08971.1 - 0.05 13.3 0.2 0.085 12.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Dimer_Tnp_hAT PF05699.9 EKG08972.1 - 2.4e-17 62.3 0.2 5.8e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-RING_3 PF14369.1 EKG08973.1 - 5.1e-06 26.3 4.5 9.3e-06 25.5 3.1 1.4 1 0 0 1 1 1 1 zinc-finger HypA PF01155.14 EKG08973.1 - 0.00062 19.4 0.9 0.00092 18.8 0.6 1.2 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-C3HC4_3 PF13920.1 EKG08973.1 - 0.0032 17.1 0.6 0.0048 16.5 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG08973.1 - 0.018 14.8 3.7 0.029 14.1 2.6 1.3 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.2 EKG08973.1 - 0.045 13.5 0.9 0.083 12.7 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4 PF00097.20 EKG08973.1 - 0.045 13.4 1.8 0.074 12.7 1.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COPI_C PF06957.6 EKG08973.1 - 0.078 11.5 0.1 0.1 11.0 0.1 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus zinc-ribbons_6 PF07191.7 EKG08973.1 - 0.12 12.1 1.4 0.2 11.4 0.9 1.3 1 0 0 1 1 1 0 zinc-ribbons Gag_p12 PF01141.13 EKG08973.1 - 0.15 12.2 0.4 0.33 11.1 0.3 1.5 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 zf-C3HC4_4 PF15227.1 EKG08973.1 - 0.15 11.9 2.3 0.25 11.2 1.6 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EKG08973.1 - 0.21 11.6 2.5 0.35 10.9 1.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PhnA_Zn_Ribbon PF08274.7 EKG08973.1 - 1.1 9.0 4.7 3.7 7.4 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Asp PF00026.18 EKG08974.1 - 3.6e-22 79.0 0.5 4.8e-22 78.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF4613 PF15390.1 EKG08976.1 - 1.4 7.0 7.5 1.4 6.9 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DDHD PF02862.12 EKG08976.1 - 2.1 8.0 10.9 2.1 8.0 7.5 1.2 1 0 0 1 1 1 0 DDHD domain Macoilin PF09726.4 EKG08976.1 - 2.8 6.1 17.7 3 6.0 12.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2146 PF10220.4 EKG08976.1 - 5.6 4.8 13.3 6.3 4.6 9.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF566 PF04484.7 EKG08976.1 - 5.8 6.3 18.6 6.6 6.1 12.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Spt5_N PF11942.3 EKG08976.1 - 6 7.5 10.6 11 6.6 7.3 1.6 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal SOBP PF15279.1 EKG08976.1 - 7.5 6.8 7.7 7.5 6.8 5.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Myb_DNA-bind_6 PF13921.1 EKG08978.1 - 0.00022 21.2 0.1 0.00063 19.7 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKG08978.1 - 0.0037 17.1 0.0 0.014 15.3 0.0 1.8 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG08978.1 - 0.0048 16.9 0.1 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain RVT_2 PF07727.9 EKG08979.1 - 5.1e-47 159.9 0.0 1.1e-46 158.7 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1523 PF07509.6 EKG08980.1 - 0.024 13.8 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) DDE_Tnp_1_7 PF13843.1 EKG08982.1 - 5.2e-13 48.7 0.6 7.3e-13 48.2 0.4 1.2 1 0 0 1 1 1 1 Transposase IS4 Pectate_lyase PF03211.8 EKG08982.1 - 1.3e-12 47.5 0.3 2.8e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 Pectate lyase FAD_binding_3 PF01494.14 EKG08985.1 - 8.4e-38 130.3 0.0 1.2e-37 129.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF819 PF05684.7 EKG08986.1 - 0.5 9.1 2.1 0.47 9.2 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) zf-C2H2_4 PF13894.1 EKG08987.1 - 8.9e-06 25.6 7.0 0.00062 19.9 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG08987.1 - 4.3e-05 23.6 1.5 4.3e-05 23.6 1.0 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG08987.1 - 0.001 19.2 2.1 0.001 19.2 1.5 2.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-CHCC PF10276.4 EKG08987.1 - 0.23 11.3 0.1 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Zinc-finger domain zf-UBP PF02148.14 EKG08987.1 - 0.95 9.6 3.4 0.42 10.7 0.8 1.6 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein TF_Zn_Ribbon PF08271.7 EKG08987.1 - 2.1 7.7 4.0 1 8.7 0.1 2.2 2 1 0 2 2 2 0 TFIIB zinc-binding Mitofilin PF09731.4 EKG08988.1 - 3.7e-06 25.9 0.2 4.4e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Baculo_PEP_C PF04513.7 EKG08988.1 - 0.00019 21.3 4.2 0.0051 16.6 0.2 2.5 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 EKG08988.1 - 0.0025 17.3 14.9 0.016 14.7 10.2 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YbaB_DNA_bd PF02575.11 EKG08988.1 - 0.013 15.3 5.0 0.55 10.1 0.3 2.6 1 1 1 2 2 2 0 YbaB/EbfC DNA-binding family FlaC_arch PF05377.6 EKG08988.1 - 0.019 14.8 3.4 2.6 8.0 0.0 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.7 EKG08988.1 - 0.05 13.3 5.7 0.1 12.3 4.0 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.9 EKG08988.1 - 0.11 11.8 2.1 0.25 10.7 1.1 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF342 PF03961.8 EKG08988.1 - 0.21 9.9 0.8 0.35 9.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 EKG08988.1 - 0.29 11.4 5.0 1.5 9.2 0.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlxA PF14282.1 EKG08988.1 - 0.39 10.6 7.1 1.2 9.1 5.0 1.7 1 1 0 1 1 1 0 FlxA-like protein DUF3138 PF11336.3 EKG08988.1 - 0.97 7.5 4.0 0.75 7.9 1.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) DUF1640 PF07798.6 EKG08988.1 - 1.3 9.0 9.7 0.12 12.4 1.6 2.3 2 1 0 3 3 2 0 Protein of unknown function (DUF1640) Phasin PF05597.6 EKG08988.1 - 1.4 8.6 5.2 1.4 8.6 1.3 2.3 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) IncA PF04156.9 EKG08988.1 - 4 6.9 11.4 10 5.6 7.9 1.7 1 1 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EKG08988.1 - 5.8 7.4 9.8 7.8 7.0 0.2 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) FUSC PF04632.7 EKG08988.1 - 6.5 5.0 8.8 9 4.5 6.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4219 PF13961.1 EKG08989.1 - 1.1e-06 27.8 0.1 1.1e-06 27.8 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EKG08989.1 - 0.0094 15.5 0.1 0.019 14.5 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type PIF1 PF05970.9 EKG08990.1 - 4e-19 68.8 0.3 1.1e-18 67.3 0.1 1.8 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EKG08990.1 - 1e-10 41.5 0.0 3.2e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG08990.1 - 0.0035 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EKG08990.1 - 0.0054 16.3 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 EKG08990.1 - 0.015 15.3 0.2 0.038 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EKG08990.1 - 0.026 14.2 0.1 0.1 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EKG08990.1 - 0.19 11.4 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase rve PF00665.21 EKG08991.1 - 5.2e-09 36.2 0.0 1.6e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EKG08991.1 - 0.0066 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.1 EKG08992.1 - 5.8e-07 28.7 1.1 1.5e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) UBN2_3 PF14244.1 EKG08992.1 - 0.00035 20.1 0.3 0.02 14.4 0.0 2.0 1 1 1 2 2 2 2 gag-polypeptide of LTR copia-type McrBC PF10117.4 EKG08993.1 - 0.09 11.6 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component Amidohydro_3 PF07969.6 EKG08996.1 - 5.2e-18 65.4 0.2 7.1e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKG08996.1 - 5.4e-06 26.1 0.1 2.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Helitron_like_N PF14214.1 EKG08998.1 - 8.6e-36 123.3 0.0 1.4e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus RVT_2 PF07727.9 EKG08999.1 - 8.5e-46 155.9 0.0 1.3e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EKG08999.1 - 8.7e-12 45.2 0.0 4e-11 43.0 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EKG08999.1 - 2.7e-06 26.9 0.0 7.3e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain RNase_H PF00075.19 EKG09000.1 - 8.5e-19 68.2 0.0 1.9e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09000.1 - 2.5e-05 23.9 0.0 8.9e-05 22.1 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase-like zf-CCHC PF00098.18 EKG09001.1 - 0.0023 17.7 3.4 0.0023 17.7 2.4 2.3 2 0 0 2 2 2 1 Zinc knuckle 7TMR-HDED PF07697.6 EKG09001.1 - 0.14 11.8 10.6 0.066 12.9 3.3 2.5 2 1 0 2 2 2 0 7TM-HD extracellular DUF924 PF06041.6 EKG09002.1 - 3.2e-36 124.8 0.9 6.1e-36 123.9 0.6 1.4 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) NmrA PF05368.8 EKG09003.1 - 0.0028 16.9 0.1 0.0032 16.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DUF4327 PF14217.1 EKG09003.1 - 0.11 12.2 5.1 3.1 7.6 0.2 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4327) RHD3 PF05879.7 EKG09004.1 - 0.00042 18.4 0.5 0.00052 18.0 0.3 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) HEPPP_synt_1 PF07307.6 EKG09004.1 - 0.02 14.3 1.0 0.031 13.7 0.7 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Apolipoprotein PF01442.13 EKG09004.1 - 0.29 10.5 11.5 0.69 9.3 8.0 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ISG65-75 PF11727.3 EKG09004.1 - 0.52 9.3 2.8 0.77 8.7 0.2 1.9 1 1 1 2 2 2 0 Invariant surface glycoprotein Apc4 PF12896.2 EKG09007.1 - 0.071 12.4 0.2 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 rve PF00665.21 EKG09008.1 - 5e-14 52.4 0.1 2e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EKG09008.1 - 8.1e-13 48.2 0.0 1.7e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EKG09008.1 - 0.069 12.8 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain 53-BP1_Tudor PF09038.5 EKG09008.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor Helicase_C PF00271.26 EKG09009.1 - 7.6e-18 64.1 0.1 1e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG09009.1 - 7.6e-16 58.0 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EKG09009.1 - 1.1e-07 31.9 0.0 1.8e-06 27.8 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EKG09009.1 - 0.0042 15.9 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3597 PF12200.3 EKG09009.1 - 0.063 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF1518 PF07469.7 EKG09010.1 - 2.9 8.0 7.4 1.5 9.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1518) DDE_3 PF13358.1 EKG09015.1 - 5.5e-07 29.4 0.7 1.2e-06 28.3 0.5 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease TraF PF13728.1 EKG09015.1 - 0.0024 17.4 0.1 0.0039 16.7 0.1 1.5 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF3410 PF11890.3 EKG09015.1 - 1.6 8.4 7.4 7.8 6.2 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) CENP-F_leu_zip PF10473.4 EKG09016.1 - 7.4e-05 22.6 35.7 0.0042 16.9 7.2 3.3 1 1 2 3 3 3 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 EKG09016.1 - 9.2e-05 20.4 13.1 9.2e-05 20.4 9.1 2.3 1 1 1 2 2 2 1 HOOK protein DUF2205 PF10224.4 EKG09016.1 - 0.00041 19.8 2.4 0.00041 19.8 1.6 4.6 2 2 2 4 4 4 1 Predicted coiled-coil protein (DUF2205) Lectin_N PF03954.9 EKG09016.1 - 0.0012 18.2 0.3 0.0012 18.2 0.2 1.9 2 1 0 2 2 2 1 Hepatic lectin, N-terminal domain DivIC PF04977.10 EKG09016.1 - 0.0014 18.0 2.1 0.0014 18.0 1.4 5.0 3 1 2 5 5 5 1 Septum formation initiator DUF972 PF06156.8 EKG09016.1 - 0.003 17.8 4.3 0.003 17.8 3.0 3.5 1 1 1 3 3 3 1 Protein of unknown function (DUF972) MAD PF05557.8 EKG09016.1 - 0.0061 14.7 28.6 0.011 13.9 19.8 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein bZIP_1 PF00170.16 EKG09016.1 - 0.011 15.6 1.2 0.011 15.6 0.8 4.6 5 1 1 6 6 6 0 bZIP transcription factor Myosin_tail_1 PF01576.14 EKG09016.1 - 0.017 12.9 34.6 0.073 10.7 17.4 2.2 1 1 1 2 2 2 0 Myosin tail Seadorna_VP6 PF07407.6 EKG09016.1 - 0.037 12.8 8.5 0.15 10.8 0.5 2.4 1 1 1 2 2 2 0 Seadornavirus VP6 protein YqaJ PF09588.5 EKG09016.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 YqaJ-like viral recombinase domain DUF1664 PF07889.7 EKG09016.1 - 0.048 13.4 20.0 0.054 13.2 2.3 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Zn_clus PF00172.13 EKG09016.1 - 0.064 13.1 5.1 1.1 9.1 0.2 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Reo_sigmaC PF04582.7 EKG09016.1 - 0.12 11.5 4.0 0.14 11.3 1.3 1.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 EKG09016.1 - 0.51 8.5 33.5 0.19 9.9 2.7 2.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF724 PF05266.9 EKG09016.1 - 1 8.9 28.8 0.1 12.1 4.9 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF724) FYDLN_acid PF09538.5 EKG09016.1 - 1.4 9.5 11.8 0.094 13.3 3.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF484 PF04340.7 EKG09016.1 - 1.4 8.2 16.0 0.53 9.7 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Tropomyosin_1 PF12718.2 EKG09016.1 - 2 8.2 34.1 1.6 8.6 6.5 3.7 1 1 3 4 4 4 0 Tropomyosin like Spc7 PF08317.6 EKG09016.1 - 2.8 6.4 30.6 3.2 6.3 4.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3560 PF12083.3 EKG09016.1 - 2.9 7.9 10.9 0.26 11.3 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3560) AAA_13 PF13166.1 EKG09016.1 - 3.1 6.1 25.1 0.098 11.0 9.7 2.1 1 1 1 2 2 2 0 AAA domain TBPIP PF07106.8 EKG09016.1 - 3.3 7.2 28.4 1 8.8 4.4 3.8 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phlebovirus_NSM PF07246.6 EKG09016.1 - 3.3 6.7 18.0 4.2 6.4 9.2 2.7 1 1 2 3 3 3 0 Phlebovirus nonstructural protein NS-M Flagellin_N PF00669.15 EKG09016.1 - 4.1 7.1 12.4 0.43 10.3 1.4 2.6 3 0 0 3 3 2 0 Bacterial flagellin N-terminal helical region WXG100 PF06013.7 EKG09016.1 - 4.8 7.2 12.7 5.9 6.9 0.2 4.3 4 1 0 4 4 4 0 Proteins of 100 residues with WXG FlaC_arch PF05377.6 EKG09016.1 - 5.3 7.0 17.7 0.11 12.3 0.8 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 EKG09016.1 - 7.6 4.8 17.7 0.38 9.1 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Ax_dynein_light PF10211.4 EKG09016.1 - 7.7 6.3 31.9 1.2 8.9 5.6 3.5 2 2 2 4 4 4 0 Axonemal dynein light chain Striatin PF08232.7 EKG09016.1 - 8.4 6.7 29.5 39 4.5 7.2 3.5 1 1 1 2 2 2 0 Striatin family Fib_alpha PF08702.5 EKG09016.1 - 9.6 6.3 20.6 3.3 7.8 6.0 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Dimer_Tnp_hAT PF05699.9 EKG09019.1 - 1.5e-15 56.5 0.0 3.4e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EKG09019.1 - 0.00047 20.0 0.3 0.0015 18.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) DDE_Tnp_1_7 PF13843.1 EKG09020.1 - 1.2e-08 34.3 0.3 1.5e-08 34.1 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 YqzE PF14038.1 EKG09020.1 - 0.12 12.0 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 YqzE-like protein RNase_H PF00075.19 EKG09021.1 - 1.1e-12 48.4 0.0 1.9e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09021.1 - 0.021 14.5 0.1 0.17 11.6 0.1 2.1 1 1 0 1 1 1 0 Reverse transcriptase-like GrpE PF01025.14 EKG09024.1 - 0.93 9.0 9.3 2.2 7.8 6.5 1.5 1 0 0 1 1 1 0 GrpE Radial_spoke_3 PF06098.6 EKG09024.1 - 4.5 6.1 16.5 3.9 6.4 9.2 2.0 2 0 0 2 2 2 0 Radial spoke protein 3 SERTA PF06031.8 EKG09027.1 - 0.0051 16.0 0.0 0.0078 15.4 0.0 1.3 1 0 0 1 1 1 1 SERTA motif Dimer_Tnp_hAT PF05699.9 EKG09031.1 - 3.6e-16 58.5 0.0 8e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EKG09031.1 - 0.02 14.8 0.3 0.05 13.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) APH PF01636.18 EKG09032.1 - 1.9e-05 24.5 0.0 2.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EKG09032.1 - 0.00011 21.4 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EKG09032.1 - 0.15 11.0 0.0 0.21 10.6 0.0 1.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Trs65 PF12735.2 EKG09034.1 - 4.1 6.6 8.7 2.7 7.1 0.1 2.1 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 Ank_2 PF12796.2 EKG09035.1 - 6.4e-126 411.0 0.0 2.7e-17 62.8 0.0 8.3 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG09035.1 - 6.7e-98 319.5 18.2 6.9e-13 48.7 0.0 12.0 3 3 9 12 12 12 12 Ankyrin repeats (many copies) Ank PF00023.25 EKG09035.1 - 4e-96 310.3 7.8 2.8e-08 33.1 0.0 15.1 15 0 0 15 15 15 15 Ankyrin repeat Ank_5 PF13857.1 EKG09035.1 - 1.9e-81 266.2 25.3 4.5e-14 52.1 0.1 10.0 3 2 9 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG09035.1 - 9.5e-79 251.4 0.0 3.1e-05 23.8 0.0 15.1 15 0 0 15 15 15 14 Ankyrin repeat TolA PF06519.6 EKG09035.1 - 0.0028 17.6 0.0 24 4.9 0.0 4.4 3 1 0 4 4 4 0 TolA C-terminal Hairy_orange PF07527.8 EKG09035.1 - 0.059 13.1 0.0 67 3.3 0.0 4.9 6 0 0 6 6 6 0 Hairy Orange G6B PF15096.1 EKG09035.1 - 0.078 12.4 0.1 82 2.5 0.0 3.9 5 0 0 5 5 5 0 G6B family KR PF08659.5 EKG09036.1 - 8.7e-54 181.9 5.9 2.3e-53 180.5 0.1 3.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EKG09036.1 - 2.4e-46 157.6 5.6 4.6e-45 153.5 0.1 3.4 3 1 0 3 3 3 1 short chain dehydrogenase Condensation PF00668.15 EKG09036.1 - 4.3e-32 111.1 0.1 5.9e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Condensation domain ADH_zinc_N PF00107.21 EKG09036.1 - 2.7e-19 68.9 0.1 5.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG09036.1 - 5.4e-11 43.4 0.0 1.6e-10 41.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EKG09036.1 - 5.8e-07 29.6 0.1 1.5e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EKG09036.1 - 0.00012 22.2 0.0 0.0004 20.6 0.0 1.9 1 1 0 1 1 1 1 HxxPF-repeated domain Hexapep_2 PF14602.1 EKG09036.1 - 0.25 10.9 1.2 5.7 6.5 0.3 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.11 EKG09037.1 - 8.4e-12 44.4 19.3 8.4e-12 44.4 13.4 2.6 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG09037.1 - 0.00026 19.3 10.4 0.00058 18.1 7.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DivIC PF04977.10 EKG09038.1 - 1.7 8.1 7.4 0.6 9.6 2.8 2.0 1 1 0 1 1 1 0 Septum formation initiator Radial_spoke_3 PF06098.6 EKG09038.1 - 8.6 5.2 12.6 13 4.6 8.7 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 zf-CCHC PF00098.18 EKG09040.1 - 0.0017 18.2 3.4 0.0017 18.2 2.4 2.5 2 0 0 2 2 2 1 Zinc knuckle RVT_1 PF00078.22 EKG09041.1 - 5e-30 104.4 0.0 8.2e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EKG09043.1 - 6.5e-21 74.6 0.0 1.2e-17 64.0 0.0 2.5 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.14 EKG09043.1 - 2.9e-09 36.3 0.0 6.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 EKG09043.1 - 7.8e-08 31.7 0.3 2e-07 30.4 0.2 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 EKG09043.1 - 4.2e-07 30.6 0.2 9.2e-06 26.3 0.0 3.0 2 1 1 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 EKG09043.1 - 1.7e-05 24.7 0.0 3.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Transposase rve PF00665.21 EKG09043.1 - 0.00035 20.6 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain HTH_29 PF13551.1 EKG09043.1 - 0.00088 19.3 0.0 0.0025 17.9 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix APH PF01636.18 EKG09044.1 - 0.0053 16.5 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_43 PF04616.9 EKG09044.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 Pkinase PF00069.20 EKG09044.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DDE_1 PF03184.14 EKG09045.1 - 0.015 14.4 0.0 0.037 13.1 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease FLO_LFY PF01698.11 EKG09045.1 - 0.76 8.5 22.0 1.1 7.9 15.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 EKG09045.1 - 1.7 6.2 14.3 2 5.9 9.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U79_P34 PF03064.11 EKG09045.1 - 4.7 6.6 27.4 9.1 5.7 19.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PLRV_ORF5 PF01690.12 EKG09045.1 - 6.6 5.7 16.9 11 5.0 11.7 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein BRI3BP PF14965.1 EKG09048.1 - 0.18 11.1 3.5 0.21 10.9 1.8 1.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 ABC2_membrane_3 PF12698.2 EKG09048.1 - 1.5 7.7 5.8 1 8.2 3.2 1.4 1 1 1 2 2 2 0 ABC-2 family transporter protein Dimer_Tnp_hAT PF05699.9 EKG09049.1 - 2.4e-19 68.7 0.0 3.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MFS_1 PF07690.11 EKG09051.1 - 2.1e-21 76.0 55.0 3.9e-16 58.7 31.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_5 PF06946.6 EKG09051.1 - 0.079 13.1 2.4 1.3 9.2 0.0 2.7 2 0 0 2 2 2 0 Phage holin MFS_1_like PF12832.2 EKG09051.1 - 0.22 11.3 12.6 0.42 10.4 1.8 3.4 3 0 0 3 3 3 0 MFS_1 like family Lactamase_B_2 PF12706.2 EKG09052.1 - 8.4e-24 84.1 0.0 1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG09052.1 - 2.3e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG09052.1 - 0.029 14.0 0.4 0.34 10.5 0.3 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Methyltransf_25 PF13649.1 EKG09056.1 - 8.9e-10 38.8 0.0 1.5e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG09056.1 - 6.4e-09 36.1 0.0 1.3e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG09056.1 - 3.4e-08 33.2 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG09056.1 - 4.3e-05 23.2 0.0 7.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG09056.1 - 8.8e-05 22.5 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG09056.1 - 0.00022 20.4 0.0 0.00031 19.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EKG09056.1 - 0.0037 17.7 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG09056.1 - 0.0039 17.7 0.0 0.0074 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EKG09056.1 - 0.0052 16.4 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CASP_C PF08172.7 EKG09057.1 - 5.3e-06 25.6 4.6 6.7e-06 25.3 3.2 1.2 1 0 0 1 1 1 1 CASP C terminal CENP-Q PF13094.1 EKG09057.1 - 9.8e-05 22.4 3.9 0.00011 22.2 2.7 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3498 PF12004.3 EKG09057.1 - 0.00063 19.0 2.8 0.0007 18.8 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) TMF_DNA_bd PF12329.3 EKG09057.1 - 0.00082 19.1 8.0 0.0013 18.5 5.5 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.8 EKG09057.1 - 0.0033 16.4 3.6 0.004 16.1 1.9 1.4 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DivIVA PF05103.8 EKG09057.1 - 0.0044 17.0 5.7 0.0059 16.6 3.9 1.2 1 0 0 1 1 1 1 DivIVA protein DUF2968 PF11180.3 EKG09057.1 - 0.0049 16.2 5.3 0.0049 16.2 3.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Fmp27_WPPW PF10359.4 EKG09057.1 - 0.0065 14.9 2.9 0.0064 14.9 2.0 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain ADIP PF11559.3 EKG09057.1 - 0.0073 16.2 5.2 0.0094 15.8 3.6 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 EKG09057.1 - 0.0074 16.2 2.4 0.01 15.7 1.6 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Lebercilin PF15619.1 EKG09057.1 - 0.011 15.2 6.6 0.016 14.6 4.6 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ArsR PF09824.4 EKG09057.1 - 0.012 14.9 0.2 0.02 14.2 0.2 1.4 1 1 0 1 1 1 0 ArsR transcriptional regulator GBP_C PF02841.9 EKG09057.1 - 0.012 14.8 5.3 0.016 14.3 3.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF16 PF01519.11 EKG09057.1 - 0.013 15.6 1.0 0.019 15.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 ATG16 PF08614.6 EKG09057.1 - 0.019 14.8 6.4 0.022 14.5 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) OmpH PF03938.9 EKG09057.1 - 0.027 14.4 2.6 0.028 14.3 1.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med21 PF11221.3 EKG09057.1 - 0.035 14.0 1.7 0.039 13.9 1.2 1.1 1 0 0 1 1 1 0 Subunit 21 of Mediator complex TPD52 PF04201.10 EKG09057.1 - 0.037 13.7 1.6 0.051 13.3 1.1 1.3 1 0 0 1 1 1 0 Tumour protein D52 family DUF932 PF06067.6 EKG09057.1 - 0.039 13.2 1.6 0.063 12.5 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) IncA PF04156.9 EKG09057.1 - 0.041 13.4 2.8 0.048 13.2 1.9 1.1 1 0 0 1 1 1 0 IncA protein NCD2 PF04905.8 EKG09057.1 - 0.057 13.2 1.3 0.078 12.7 0.9 1.3 1 1 0 1 1 1 0 NAB conserved region 2 (NCD2) MbeD_MobD PF04899.7 EKG09057.1 - 0.058 13.3 4.6 1.3 8.9 0.2 2.3 1 1 1 2 2 2 0 MbeD/MobD like APG6 PF04111.7 EKG09057.1 - 0.069 12.1 4.0 0.078 12.0 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Nsp1_C PF05064.8 EKG09057.1 - 0.076 12.6 2.2 0.13 11.9 1.5 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region PhoU PF01895.14 EKG09057.1 - 0.098 13.1 3.6 0.2 12.1 2.5 1.6 1 1 0 1 1 1 0 PhoU domain Jnk-SapK_ap_N PF09744.4 EKG09057.1 - 0.099 12.6 5.8 0.13 12.2 4.0 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc42p PF11544.3 EKG09057.1 - 0.11 12.5 2.6 0.24 11.3 1.8 1.7 1 1 0 1 1 1 0 Spindle pole body component Spc42p DUF641 PF04859.7 EKG09057.1 - 0.18 11.5 4.1 0.23 11.2 2.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ACCA PF03255.9 EKG09057.1 - 0.26 10.8 2.5 0.39 10.2 1.8 1.3 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit FYVE_2 PF02318.11 EKG09057.1 - 0.31 10.9 5.3 0.24 11.2 2.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger DUF948 PF06103.6 EKG09057.1 - 0.42 10.4 4.8 3.6 7.5 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TBCA PF02970.11 EKG09057.1 - 0.5 10.4 6.9 0.68 10.0 4.8 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor A DivIC PF04977.10 EKG09057.1 - 2.2 7.8 7.7 3.4 7.2 2.2 2.2 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.7 EKG09057.1 - 2.6 8.5 8.0 6.4 7.2 4.0 2.5 1 1 1 2 2 2 0 SlyX DUF972 PF06156.8 EKG09057.1 - 2.9 8.2 6.1 5.5 7.3 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) XhlA PF10779.4 EKG09057.1 - 3 7.8 5.8 8.6 6.3 4.0 1.8 1 1 0 1 1 1 0 Haemolysin XhlA Atg14 PF10186.4 EKG09057.1 - 7.7 5.3 8.2 5.8 5.7 5.0 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FAD_binding_8 PF08022.7 EKG09058.1 - 4.8e-25 87.4 0.0 1e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EKG09058.1 - 8.3e-24 84.2 0.0 1.3e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EKG09058.1 - 1.6e-17 63.7 9.7 1.6e-17 63.7 6.7 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EKG09058.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EKG09058.1 - 0.086 13.4 0.0 1.9 9.1 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4066 PF13278.1 EKG09059.1 - 1.8e-14 53.3 0.1 2.2e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EKG09059.1 - 1.3e-06 27.9 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.9 EKG09059.1 - 0.027 14.0 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF4551 PF15087.1 EKG09060.1 - 0.95 7.7 4.8 1.1 7.5 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TT_ORF2 PF02957.10 EKG09060.1 - 6.8 7.4 9.2 1.4 9.6 2.1 2.0 1 1 1 2 2 2 0 TT viral ORF2 DUF4407 PF14362.1 EKG09060.1 - 8.7 5.1 9.8 10 4.9 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDE_1 PF03184.14 EKG09061.1 - 6.5e-38 130.0 0.0 1.1e-37 129.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EKG09061.1 - 3.5e-08 33.1 0.0 2.3e-07 30.5 0.0 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG09061.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Gti1_Pac2 PF09729.4 EKG09062.1 - 1.1e-51 175.1 3.4 5.8e-42 143.4 0.3 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Pico_P1A PF02226.11 EKG09062.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) p450 PF00067.17 EKG09064.1 - 2e-42 145.2 0.0 2.6e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MinE PF03776.9 EKG09064.1 - 0.088 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Gln-synt_C PF00120.19 EKG09068.1 - 1.8e-33 115.7 0.0 2.1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Calreticulin PF00262.13 EKG09070.1 - 0.045 12.4 0.5 0.065 11.8 0.3 1.2 1 0 0 1 1 1 0 Calreticulin family Menin PF05053.8 EKG09070.1 - 0.11 10.6 1.7 0.13 10.4 1.2 1.0 1 0 0 1 1 1 0 Menin Paramyxo_C PF01692.13 EKG09071.1 - 0.66 9.5 4.8 13 5.3 0.8 2.5 2 1 0 2 2 2 0 Paramyxovirus non-structural protein c DDE_Tnp_1_7 PF13843.1 EKG09073.1 - 1.1e-24 87.1 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Exo_endo_phos_2 PF14529.1 EKG09074.1 - 1.3e-14 53.7 0.0 5e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EKG09074.1 - 2.9e-12 46.3 0.0 7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EKG09075.1 - 1.1e-47 162.0 0.1 2.5e-47 160.9 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EKG09077.1 - 1.1e-11 44.1 3.0 1.8e-11 43.5 2.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain HisG_C PF08029.6 EKG09077.1 - 0.028 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 HisG, C-terminal domain zf-CCHC PF00098.18 EKG09078.1 - 0.0017 18.2 3.4 0.0017 18.2 2.4 2.4 3 0 0 3 3 3 1 Zinc knuckle PRiA4_ORF3 PF07929.6 EKG09079.1 - 5.1e-25 87.9 1.7 5.7e-24 84.4 1.2 2.0 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.13 EKG09079.1 - 6.9e-10 38.6 19.3 6.9e-10 38.6 13.4 1.8 2 0 0 2 2 2 1 MYND finger DUF2493 PF10686.4 EKG09079.1 - 0.078 12.5 0.1 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) HTH_psq PF05225.11 EKG09080.1 - 1.9e-10 40.0 0.4 2.9e-10 39.5 0.3 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EKG09080.1 - 0.0029 17.1 0.4 0.0045 16.5 0.3 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EKG09080.1 - 0.0062 16.5 0.3 0.0098 15.8 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain UPF0175 PF03683.8 EKG09080.1 - 0.012 15.0 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) HTH_37 PF13744.1 EKG09080.1 - 0.016 15.0 0.2 0.024 14.4 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AsnC-type PF13404.1 EKG09080.1 - 0.055 13.0 0.5 0.11 12.0 0.3 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain NUMOD1 PF07453.8 EKG09080.1 - 0.062 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 NUMOD1 domain DUF445 PF04286.7 EKG09081.1 - 0.00096 18.7 2.6 0.0014 18.2 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) GerPC PF10737.4 EKG09081.1 - 0.073 12.8 0.8 0.14 11.9 0.6 1.6 1 1 0 1 1 1 0 Spore germination protein GerPC Sugarporin_N PF11471.3 EKG09081.1 - 1.5 8.4 6.0 4 7.1 0.1 2.6 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension HTH_Tnp_Tc3_2 PF01498.13 EKG09082.1 - 3.8e-08 33.2 0.6 6.2e-08 32.5 0.4 1.4 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.1 EKG09082.1 - 0.00054 20.7 0.4 0.00093 19.9 0.3 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.1 EKG09082.1 - 0.0045 16.3 0.0 0.0086 15.4 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_29 PF13551.1 EKG09082.1 - 0.0088 16.1 0.2 0.012 15.7 0.1 1.4 1 1 0 1 1 1 1 Winged helix-turn helix LRV_FeS PF05484.6 EKG09082.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster DDE_1 PF03184.14 EKG09083.1 - 5.5e-45 153.1 0.0 1.5e-44 151.7 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_psq PF05225.11 EKG09083.1 - 3.3e-10 39.3 0.6 6.2e-10 38.4 0.4 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EKG09083.1 - 2.1e-08 33.8 2.7 4.1e-08 32.9 0.0 2.7 3 1 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 EKG09083.1 - 8.1e-08 32.1 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_3 PF01381.17 EKG09083.1 - 8.5e-05 22.3 0.1 0.00031 20.5 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.1 EKG09083.1 - 0.037 14.2 1.5 0.1 12.8 0.2 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_37 PF13744.1 EKG09083.1 - 0.057 13.2 0.5 0.1 12.4 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EKG09083.1 - 0.061 12.9 2.9 0.11 12.2 0.3 2.5 3 0 0 3 3 3 0 Homeodomain-like domain CENP-B_N PF04218.8 EKG09083.1 - 0.069 12.5 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 EKG09083.1 - 0.093 12.7 0.3 0.95 9.5 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain YlaH PF14036.1 EKG09085.1 - 0.075 13.1 1.3 2.7 8.1 0.2 2.1 2 0 0 2 2 2 0 YlaH-like protein SLAC1 PF03595.12 EKG09085.1 - 0.19 10.3 6.4 0.25 9.9 4.5 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel p450 PF00067.17 EKG09086.1 - 2.9e-30 105.1 0.0 1.8e-29 102.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Lactamase_B_2 PF12706.2 EKG09087.1 - 1.6e-26 93.1 0.0 1.9e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG09087.1 - 9.5e-14 51.4 0.0 1.2e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG09087.1 - 0.0039 16.8 1.2 0.017 14.7 0.9 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RNase_H PF00075.19 EKG09088.1 - 1.6e-16 60.8 0.0 3.2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09088.1 - 0.00067 19.3 0.0 0.0023 17.6 0.0 2.0 1 0 0 1 1 1 1 Reverse transcriptase-like zf-CCHC PF00098.18 EKG09089.1 - 0.0043 16.9 4.4 0.0092 15.8 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle MIP PF00230.15 EKG09092.1 - 1.4e-13 50.8 0.9 2.9e-13 49.8 0.6 1.5 1 1 0 1 1 1 1 Major intrinsic protein Porin_OmpL1 PF11389.3 EKG09092.1 - 0.022 13.8 0.6 0.033 13.2 0.4 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 DUF3815 PF12821.2 EKG09092.1 - 1.4 8.8 11.6 1.1 9.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3815) Asp PF00026.18 EKG09093.1 - 1.4e-23 83.6 0.7 1.7e-23 83.3 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG09093.1 - 0.091 13.2 0.2 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Aspartyl protease Dimer_Tnp_hAT PF05699.9 EKG09095.1 - 1.6e-17 62.9 0.1 3.1e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF963 PF06131.6 EKG09098.1 - 0.32 10.3 17.2 0.52 9.6 11.9 1.4 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) HTH_Tnp_Tc5 PF03221.11 EKG09101.1 - 2.7e-16 59.1 0.1 4.3e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG09101.1 - 0.005 16.3 0.0 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 helix-turn-helix, Psq domain Pro-rich_19 PF15455.1 EKG09101.1 - 0.012 14.6 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 0 Proline-rich 19 HTH_28 PF13518.1 EKG09101.1 - 0.029 14.3 0.0 0.083 12.9 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain CENP-B_N PF04218.8 EKG09101.1 - 0.078 12.4 0.0 0.22 10.9 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MIP-T3 PF10243.4 EKG09102.1 - 0.36 9.2 38.5 0.48 8.8 26.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 OmpH PF03938.9 EKG09102.1 - 2.2 8.1 29.5 3.1 7.7 20.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Asp-B-Hydro_N PF05279.6 EKG09102.1 - 2.6 7.8 24.9 3.3 7.5 17.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S46 PF10459.4 EKG09102.1 - 2.7 6.2 19.2 3.1 6.1 13.3 1.1 1 0 0 1 1 1 0 Peptidase S46 CDC45 PF02724.9 EKG09102.1 - 4.2 5.2 17.5 5 5.0 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EKG09102.1 - 4.2 6.6 22.1 6.5 6.0 15.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2514 PF10721.4 EKG09102.1 - 6.4 6.4 30.3 10 5.8 21.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) UPF0560 PF10577.4 EKG09102.1 - 6.5 4.8 18.3 7.7 4.6 12.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2778 PF10908.3 EKG09103.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) DDE_Tnp_1_assoc PF13808.1 EKG09103.1 - 0.13 11.8 0.1 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-associated MULE PF10551.4 EKG09104.1 - 1.3e-13 50.9 0.0 2.2e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EKG09104.1 - 0.0015 17.1 0.0 0.0029 16.2 0.0 1.4 2 0 0 2 2 2 1 Transposase, Mutator family BTG PF07742.7 EKG09107.1 - 0.061 12.8 1.6 0.079 12.4 1.1 1.2 1 0 0 1 1 1 0 BTG family DYW_deaminase PF14432.1 EKG09107.1 - 3.5 7.6 8.5 4.5 7.3 5.8 1.4 1 1 0 1 1 1 0 DYW family of nucleic acid deaminases Arrestin_N PF00339.24 EKG09108.1 - 8.3e-09 35.4 0.0 8.9e-08 32.0 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKG09108.1 - 1.1e-07 31.9 0.0 7.8e-06 26.0 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF4611 PF15387.1 EKG09110.1 - 0.012 15.7 9.7 0.11 12.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LAT PF15234.1 EKG09110.1 - 0.036 13.5 0.3 0.036 13.5 0.2 1.9 1 1 1 2 2 2 0 Linker for activation of T-cells S-antigen PF05756.6 EKG09110.1 - 0.14 12.1 9.3 0.48 10.4 0.3 2.2 2 0 0 2 2 2 0 S-antigen protein Prothymosin PF03247.9 EKG09110.1 - 0.44 10.7 19.7 0.44 10.7 3.3 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family CENP-B_dimeris PF09026.5 EKG09110.1 - 0.5 10.6 13.2 0.96 9.7 1.2 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EKG09110.1 - 2.7 7.5 13.5 0.7 9.4 0.8 2.2 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EKG09110.1 - 5.4 7.3 15.2 1.3 9.4 1.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AF1Q PF15017.1 EKG09110.1 - 7.4 6.5 8.7 9.2 6.2 1.4 2.2 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator E1-E2_ATPase PF00122.15 EKG09111.1 - 9.5e-57 191.6 1.2 9.5e-57 191.6 0.8 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG09111.1 - 2.9e-43 147.4 9.8 2.9e-43 147.4 6.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG09111.1 - 5.6e-30 105.3 0.0 2.9e-29 103.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG09111.1 - 5.6e-17 61.4 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EKG09111.1 - 1.7e-15 57.6 0.0 3.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG09111.1 - 2.3e-07 30.6 0.1 1.8e-05 24.4 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKG09111.1 - 2.5e-06 26.8 0.0 7.3e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF3325 PF11804.3 EKG09111.1 - 0.061 13.2 0.0 0.061 13.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) DUF2207 PF09972.4 EKG09111.1 - 0.73 8.3 4.3 0.67 8.4 0.4 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) RNase_H PF00075.19 EKG09112.1 - 8.7e-13 48.7 0.0 1.6e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09112.1 - 0.0015 18.2 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 EKG09113.1 - 1.3e-10 41.7 0.0 2.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09113.1 - 0.0038 16.9 0.0 0.013 15.2 0.0 1.9 1 0 0 1 1 1 1 Reverse transcriptase-like DUF4066 PF13278.1 EKG09114.1 - 2.5e-11 43.1 0.0 4.1e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EKG09114.1 - 0.0034 16.8 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Dimer_Tnp_hAT PF05699.9 EKG09115.1 - 1.2e-17 63.2 0.1 2.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EKG09115.1 - 0.019 14.9 0.3 0.049 13.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Serinc PF03348.10 EKG09116.1 - 0.075 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Myb_DNA-bind_6 PF13921.1 EKG09119.1 - 0.00018 21.5 0.1 0.00063 19.7 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKG09119.1 - 0.0036 17.1 0.0 0.013 15.4 0.0 1.8 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG09119.1 - 0.0049 16.8 0.0 0.011 15.8 0.0 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Patatin PF01734.17 EKG09120.1 - 1.9e-06 27.9 0.1 6.8e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase Patatin PF01734.17 EKG09121.1 - 1.2e-05 25.2 0.0 1.8e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase YABBY PF04690.8 EKG09121.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 YABBY protein Dicty_CAR PF05462.6 EKG09126.1 - 0.0015 17.4 0.8 0.0015 17.4 0.6 1.7 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7TM_GPCR_Srh PF10318.4 EKG09126.1 - 0.049 12.4 1.3 0.1 11.3 0.4 1.9 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh PIRT PF15099.1 EKG09126.1 - 0.4 9.9 3.2 0.2 10.8 0.5 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family FAD_binding_8 PF08022.7 EKG09128.1 - 1.8e-11 43.8 0.0 9e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EKG09128.1 - 3.6e-09 36.7 8.9 3.6e-09 36.7 6.2 2.6 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EKG09128.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF4405 PF14358.1 EKG09128.1 - 0.13 12.3 10.4 0.28 11.3 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) CALCOCO1 PF07888.6 EKG09129.1 - 0.0012 17.1 3.1 0.0014 16.9 2.2 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like HAP1_N PF04849.8 EKG09129.1 - 0.005 15.8 5.1 0.011 14.6 3.4 1.5 1 1 0 1 1 1 1 HAP1 N-terminal conserved region CASP_C PF08172.7 EKG09129.1 - 0.0062 15.5 6.8 0.011 14.8 4.6 1.5 1 1 0 1 1 1 1 CASP C terminal IncA PF04156.9 EKG09129.1 - 0.0079 15.8 2.5 0.0099 15.4 1.7 1.2 1 0 0 1 1 1 1 IncA protein Fmp27_WPPW PF10359.4 EKG09129.1 - 0.013 13.8 5.3 0.015 13.7 3.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMCO5 PF14992.1 EKG09129.1 - 0.015 14.4 3.8 0.018 14.1 2.7 1.1 1 0 0 1 1 1 0 TMCO5 family GBP_C PF02841.9 EKG09129.1 - 0.051 12.7 7.3 0.064 12.4 5.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Baculo_PEP_C PF04513.7 EKG09129.1 - 0.061 13.1 5.1 0.085 12.6 3.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC PF05010.9 EKG09129.1 - 0.061 13.0 6.0 0.08 12.6 4.1 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) TMF_DNA_bd PF12329.3 EKG09129.1 - 0.067 13.0 8.7 0.13 12.0 6.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Allexi_40kDa PF05549.6 EKG09129.1 - 0.14 11.4 6.0 0.2 10.9 4.1 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spc42p PF11544.3 EKG09129.1 - 0.14 12.0 2.1 2.1 8.3 1.1 2.4 1 1 1 2 2 2 0 Spindle pole body component Spc42p DivIVA PF05103.8 EKG09129.1 - 0.16 12.0 12.1 0.44 10.6 8.4 1.7 1 1 0 1 1 1 0 DivIVA protein PhoU PF01895.14 EKG09129.1 - 0.17 12.3 4.3 0.48 10.8 2.9 2.0 1 1 0 1 1 1 0 PhoU domain ADIP PF11559.3 EKG09129.1 - 0.17 11.7 10.9 0.35 10.7 7.0 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EKG09129.1 - 0.29 10.1 6.0 0.37 9.7 4.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-Q PF13094.1 EKG09129.1 - 0.41 10.6 14.0 0.25 11.3 8.0 1.8 2 1 0 2 2 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cep57_CLD_2 PF14197.1 EKG09129.1 - 0.54 10.2 6.3 0.13 12.2 1.8 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Atg14 PF10186.4 EKG09129.1 - 0.56 9.0 6.3 0.78 8.6 4.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MMPL PF03176.10 EKG09129.1 - 1.1 7.9 4.9 1.2 7.7 3.4 1.2 1 0 0 1 1 1 0 MMPL family DUF2968 PF11180.3 EKG09129.1 - 1.7 7.9 14.1 0.55 9.5 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF948 PF06103.6 EKG09129.1 - 2.1 8.2 6.0 4.7 7.1 0.4 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NifQ PF04891.7 EKG09129.1 - 6.6 6.8 8.7 7.8 6.6 3.6 2.0 1 1 1 2 2 2 0 NifQ AAA_14 PF13173.1 EKG09131.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MgtE_N PF03448.12 EKG09133.1 - 0.046 14.0 0.3 0.061 13.6 0.2 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain FA_desaturase PF00487.19 EKG09134.1 - 6.4e-19 68.3 11.5 6.4e-19 68.3 7.9 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EKG09134.1 - 1.7e-14 53.3 0.0 7.8e-14 51.2 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Fungal_trans PF04082.13 EKG09135.1 - 3.5e-06 26.0 0.2 6.2e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MULE PF10551.4 EKG09137.1 - 1.2e-11 44.6 0.1 4.4e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.12 EKG09137.1 - 6.3e-07 28.7 0.1 1.5e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 SWIM zinc finger Peptidase_S9 PF00326.16 EKG09138.1 - 0.00013 21.2 0.0 0.00015 21.0 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG09138.1 - 0.005 16.5 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG09138.1 - 0.067 13.0 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Exonuc_VII_S PF02609.11 EKG09140.1 - 0.12 12.1 0.1 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Exonuclease VII small subunit Acyl_transf_1 PF00698.16 EKG09141.1 - 8.9e-84 281.5 0.0 2e-82 277.0 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EKG09141.1 - 6.1e-37 125.7 0.0 1.5e-36 124.4 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EKG09141.1 - 5.9e-32 109.2 0.5 1.9e-31 107.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EKG09141.1 - 2.6e-23 82.2 0.1 7.5e-23 80.7 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EKG09141.1 - 1.3e-05 24.5 0.1 0.00018 20.7 0.1 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase PCIF1_WW PF12237.3 EKG09141.1 - 0.05 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain FAD_binding_4 PF01565.18 EKG09143.1 - 1.1e-18 67.0 2.4 3.1e-18 65.5 1.7 1.8 1 0 0 1 1 1 1 FAD binding domain UbiD PF01977.11 EKG09145.1 - 5.4e-115 384.1 0.0 6.3e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.14 EKG09146.1 - 1e-16 60.7 0.4 1.7e-16 60.0 0.3 1.3 1 0 0 1 1 1 1 Flavoprotein RNA_pol_Rpb1_R PF05001.8 EKG09147.1 - 0.012 15.6 1.2 0.012 15.6 0.8 2.2 3 0 0 3 3 3 0 RNA polymerase Rpb1 C-terminal repeat APOC4 PF15119.1 EKG09151.1 - 0.089 12.7 0.2 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein C4 RNase_H PF00075.19 EKG09153.1 - 8.1e-13 48.8 0.0 1e-12 48.5 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09153.1 - 5.4e-05 22.9 0.1 0.0041 16.8 0.1 2.4 1 1 0 1 1 1 1 Reverse transcriptase-like MADF_DNA_bdg PF10545.4 EKG09155.1 - 2.2 8.5 4.7 18 5.6 0.4 3.1 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Helitron_like_N PF14214.1 EKG09158.1 - 1e-33 116.5 0.0 1.6e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EKG09160.1 - 1.7e-18 66.7 0.5 5.7e-18 65.0 0.2 2.1 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EKG09160.1 - 5.7e-10 39.0 0.0 2e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG09160.1 - 0.0009 19.3 0.4 0.0047 17.0 0.0 2.2 2 1 1 3 3 3 1 AAA domain Helicase_RecD PF05127.9 EKG09160.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Helicase AAA_16 PF13191.1 EKG09160.1 - 0.05 13.5 0.8 0.13 12.1 0.1 2.1 2 1 1 3 3 3 0 AAA ATPase domain AAA_5 PF07728.9 EKG09160.1 - 0.085 12.5 0.0 0.38 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EKG09160.1 - 0.15 11.7 0.0 0.42 10.2 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase DUF4066 PF13278.1 EKG09161.1 - 3.5e-17 62.1 0.1 4.2e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EKG09161.1 - 2.1e-07 30.5 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.9 EKG09161.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain zf-ribbon_3 PF13248.1 EKG09162.1 - 0.5 9.6 6.9 1.9 7.7 0.4 2.6 2 0 0 2 2 2 0 zinc-ribbon domain RVT_1 PF00078.22 EKG09163.1 - 6.5e-38 130.2 0.0 9.6e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EKG09163.1 - 3e-13 49.4 0.0 8.3e-13 47.9 0.0 1.8 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EKG09163.1 - 8.2e-09 35.7 0.4 1.6e-08 34.7 0.3 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNase_H PF00075.19 EKG09164.1 - 7.8e-12 45.6 0.2 1.3e-11 44.9 0.2 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09164.1 - 0.00075 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like 14-3-3 PF00244.15 EKG09165.1 - 1.1e-85 286.4 0.4 1.3e-85 286.2 0.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DDE_3 PF13358.1 EKG09167.1 - 4.8e-22 78.2 0.0 8.4e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 EKG09167.1 - 7.2e-06 25.9 0.8 1.4e-05 25.0 0.6 1.5 1 0 0 1 1 1 1 Transposase HTH_24 PF13412.1 EKG09167.1 - 0.008 15.5 0.0 0.039 13.3 0.0 2.2 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding rve PF00665.21 EKG09167.1 - 0.035 14.2 0.1 0.16 12.1 0.0 2.1 2 1 0 2 2 2 0 Integrase core domain SICA_alpha PF12887.2 EKG09167.1 - 0.039 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 SICA extracellular alpha domain Dimer_Tnp_hAT PF05699.9 EKG09168.1 - 8e-21 73.4 0.0 2.1e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Toxin_52 PF15605.1 EKG09168.1 - 0.055 13.3 0.1 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative toxin 52 zf-BED PF02892.10 EKG09170.1 - 0.0022 17.6 0.1 0.0047 16.6 0.1 1.5 1 0 0 1 1 1 1 BED zinc finger DUF4451 PF14616.1 EKG09170.1 - 0.15 11.8 1.7 0.19 11.4 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) DUF4066 PF13278.1 EKG09171.1 - 1.4e-20 73.2 0.0 1.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EKG09171.1 - 8.9e-10 38.2 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family RNase_H PF00075.19 EKG09173.1 - 0.016 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 RNase H zf-RVT PF13966.1 EKG09173.1 - 0.029 14.6 0.5 0.13 12.6 0.1 2.0 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase GST_C PF00043.20 EKG09175.1 - 3.5e-09 36.5 0.0 6.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EKG09175.1 - 2.5e-08 33.9 0.0 5.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EKG09175.1 - 2.7e-07 30.7 0.0 1.7e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG09175.1 - 1.2e-06 28.9 0.0 3.4e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG09175.1 - 1.9e-05 24.4 0.3 3.8e-05 23.4 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG09175.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 EKG09176.1 - 1e-36 126.4 0.0 7.8e-36 123.5 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 AT_hook PF02178.14 EKG09177.1 - 0.02 14.5 5.2 0.064 12.9 3.6 1.9 1 0 0 1 1 1 0 AT hook motif DDE_5 PF13546.1 EKG09177.1 - 0.27 10.0 1.3 0.34 9.7 0.9 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF924 PF06041.6 EKG09178.1 - 8e-37 126.8 0.5 1.4e-36 126.0 0.4 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) NmrA PF05368.8 EKG09179.1 - 1.4e-12 47.3 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family MULE PF10551.4 EKG09180.1 - 6.5e-09 35.8 0.2 1.9e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 MULE transposase domain JmjN PF02375.12 EKG09183.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 jmjN domain Bromodomain PF00439.20 EKG09184.1 - 3e-26 91.1 1.9 6e-26 90.1 1.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EKG09184.1 - 3e-09 36.7 0.0 6.1e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG09184.1 - 2.2e-08 34.1 0.2 6e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG09184.1 - 0.008 15.9 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein HAP1_N PF04849.8 EKG09185.1 - 0.019 13.9 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region ATG16 PF08614.6 EKG09185.1 - 0.087 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tmpp129 PF10272.4 EKG09185.1 - 0.34 9.5 7.3 0.48 9.1 5.1 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF4547 PF15080.1 EKG09187.1 - 0.1 11.9 0.0 2.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4547) Exo_endo_phos_2 PF14529.1 EKG09193.1 - 3.2e-19 68.7 0.1 6.5e-19 67.6 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EKG09193.1 - 6.6e-12 45.9 0.3 8.6e-12 45.5 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EKG09194.1 - 0.0022 17.8 3.4 0.0022 17.8 2.4 2.2 2 0 0 2 2 2 1 Zinc knuckle 7TMR-HDED PF07697.6 EKG09194.1 - 0.35 10.5 10.4 0.067 12.9 4.0 1.9 2 0 0 2 2 2 0 7TM-HD extracellular SfsA PF03749.8 EKG09195.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Sugar fermentation stimulation protein Dimer_Tnp_hAT PF05699.9 EKG09196.1 - 2.4e-14 52.7 0.0 5.9e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Talin_middle PF09141.5 EKG09196.1 - 0.22 11.1 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Talin, middle domain DDE_1 PF03184.14 EKG09198.1 - 1.9e-08 33.7 0.0 3.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EKG09198.1 - 5.7e-08 32.4 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG09198.1 - 3.6e-06 26.4 0.1 6.9e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Dimer_Tnp_hAT PF05699.9 EKG09199.1 - 7.6e-18 63.9 0.0 2.1e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1677 PF07911.8 EKG09199.1 - 0.039 14.1 3.2 0.11 12.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) HET PF06985.6 EKG09203.1 - 1.3e-22 80.4 0.0 2.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4560 PF15118.1 EKG09203.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) Ctr PF04145.10 EKG09206.1 - 6.2e-16 58.7 0.1 7.4e-16 58.5 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Neurensin PF14927.1 EKG09206.1 - 0.0061 15.9 0.3 0.0077 15.6 0.2 1.1 1 0 0 1 1 1 1 Neurensin Transgly_assoc PF04226.8 EKG09206.1 - 0.053 13.6 0.4 0.084 12.9 0.3 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein 3-HAO PF06052.7 EKG09207.1 - 2e-56 189.5 0.0 2.6e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase DZR PF12773.2 EKG09207.1 - 0.001 18.8 6.9 0.002 17.8 4.8 1.5 1 0 0 1 1 1 1 Double zinc ribbon Cupin_1 PF00190.17 EKG09207.1 - 0.0032 16.9 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Nudix_N_2 PF14803.1 EKG09207.1 - 0.018 14.7 2.6 0.58 9.9 0.2 2.5 2 0 0 2 2 2 0 Nudix N-terminal zf-ribbon_3 PF13248.1 EKG09207.1 - 0.021 14.0 5.4 0.052 12.7 2.6 2.2 1 1 1 2 2 2 0 zinc-ribbon domain Cupin_2 PF07883.6 EKG09207.1 - 0.023 14.1 0.0 0.052 13.0 0.0 1.5 1 1 0 1 1 1 0 Cupin domain FdhE PF04216.7 EKG09207.1 - 0.025 14.3 2.2 0.031 13.9 1.5 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation AraC_binding PF02311.14 EKG09207.1 - 0.087 12.5 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 AraC-like ligand binding domain DUF2296 PF10058.4 EKG09207.1 - 0.17 11.6 1.5 6.7 6.5 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-NADH-PPase PF09297.6 EKG09207.1 - 0.57 9.7 6.5 0.63 9.5 0.3 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 EKG09207.1 - 1.9 8.0 10.0 7.9 6.1 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EKG09207.1 - 2.1 8.0 7.6 0.33 10.6 0.6 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain RRN7 PF11781.3 EKG09207.1 - 5 6.7 8.2 1 8.9 2.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 ORC3_N PF07034.6 EKG09208.1 - 2.2e-40 138.6 0.0 8.7e-40 136.6 0.0 2.0 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Phage_int_SAM_4 PF13495.1 EKG09208.1 - 0.0088 16.3 1.3 0.22 11.8 0.4 3.0 3 0 0 3 3 3 1 Phage integrase, N-terminal SAM-like domain HAUS4 PF14735.1 EKG09209.1 - 0.0016 17.7 0.5 0.0097 15.2 0.0 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 DUF607 PF04678.8 EKG09209.1 - 0.011 15.7 1.2 0.14 12.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF607 RskA PF10099.4 EKG09209.1 - 0.033 13.9 0.2 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Mating_N PF12731.2 EKG09209.1 - 0.047 13.5 0.8 0.11 12.3 0.5 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 DUF2077 PF09850.4 EKG09209.1 - 0.074 12.4 0.1 0.074 12.4 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) L27_1 PF09058.5 EKG09209.1 - 0.27 11.1 2.7 0.21 11.4 0.2 2.2 2 0 0 2 2 2 0 L27_1 T2SF PF00482.18 EKG09209.1 - 0.4 10.6 1.8 1 9.2 1.2 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Spc7 PF08317.6 EKG09209.1 - 0.4 9.3 4.6 0.54 8.8 3.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein THOC7 PF05615.8 EKG09209.1 - 1.3 9.2 9.1 13 6.0 6.3 2.2 1 1 0 1 1 1 0 Tho complex subunit 7 SelP_N PF04592.9 EKG09209.1 - 2.1 7.6 7.4 3.7 6.8 5.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region adh_short PF00106.20 EKG09211.1 - 2.2e-23 83.0 6.7 1.4e-14 54.3 0.7 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EKG09211.1 - 7.5e-21 74.9 0.2 4.6e-11 42.9 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG09211.1 - 2.4e-11 43.6 3.8 1.7e-09 37.6 0.3 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EKG09211.1 - 0.0043 16.5 0.2 0.013 14.9 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG09211.1 - 0.022 14.7 0.2 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EKG09211.1 - 0.1 12.2 0.5 0.36 10.4 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CKS PF01111.14 EKG09213.1 - 7.2e-34 115.4 1.5 1.1e-33 114.8 1.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit WD40 PF00400.27 EKG09215.1 - 5e-29 99.0 7.1 7e-07 28.8 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EKG09215.1 - 6e-05 21.3 0.5 0.0045 15.1 1.3 3.0 3 1 0 3 3 3 1 Nucleoporin Nup120/160 HA2 PF04408.18 EKG09216.1 - 5.6e-26 90.5 0.0 2.4e-25 88.4 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EKG09216.1 - 6.7e-23 80.7 0.0 2.1e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EKG09216.1 - 1.2e-13 50.6 0.0 3e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG09216.1 - 1.3e-07 31.2 0.1 7.3e-07 28.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKG09216.1 - 4.9e-05 23.4 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EKG09216.1 - 0.00027 20.8 0.0 0.19 11.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EKG09216.1 - 0.00032 19.6 0.7 0.0012 17.8 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein SRP54 PF00448.17 EKG09216.1 - 0.002 17.6 0.4 0.0057 16.1 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EKG09216.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.4 EKG09216.1 - 0.0076 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EKG09216.1 - 0.011 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EKG09216.1 - 0.014 15.2 0.2 0.091 12.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EKG09216.1 - 0.016 14.8 1.8 0.69 9.5 0.1 3.0 3 0 0 3 3 3 0 NACHT domain G-alpha PF00503.15 EKG09216.1 - 0.035 12.8 0.1 0.065 11.9 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 EKG09216.1 - 0.063 12.9 1.1 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EKG09216.1 - 0.066 12.0 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain Glug PF07581.7 EKG09216.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 The GLUG motif AAA_17 PF13207.1 EKG09216.1 - 0.18 12.6 0.7 0.88 10.3 0.2 2.5 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EKG09216.1 - 0.44 10.8 3.7 0.62 10.3 0.0 2.7 4 0 0 4 4 2 0 AAA domain PP2C_2 PF13672.1 EKG09217.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKG09217.1 - 0.00018 21.3 0.0 0.00043 20.0 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EKG09217.1 - 0.00057 19.3 0.0 0.049 13.0 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C HET PF06985.6 EKG09218.1 - 3.5e-18 66.1 0.0 1.1e-17 64.5 0.0 1.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF3712 PF12505.3 EKG09219.1 - 2.9e-30 104.8 0.1 2.9e-30 104.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EKG09219.1 - 0.031 14.6 1.4 0.71 10.2 0.2 2.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein DUF4187 PF13821.1 EKG09220.1 - 1.1e-20 72.9 3.9 4.4e-20 71.0 2.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EKG09220.1 - 1.3e-11 44.1 4.3 1.3e-11 44.1 3.0 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EKG09220.1 - 2.1e-05 24.2 4.3 2.1e-05 24.2 2.9 2.9 2 1 0 3 3 3 1 DExH-box splicing factor binding site Troponin PF00992.15 EKG09220.1 - 0.0071 16.4 7.0 0.0071 16.4 4.9 2.6 3 0 0 3 3 3 1 Troponin Rotamase_2 PF13145.1 EKG09220.1 - 1.6 9.3 9.7 1.1 9.9 1.4 2.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF1068 PF06364.7 EKG09220.1 - 2.5 7.6 10.4 0.19 11.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) WD40 PF00400.27 EKG09221.1 - 5.4e-48 159.2 21.7 1.1e-10 40.9 0.4 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EKG09221.1 - 5.8e-14 51.0 6.7 1.1e-13 50.2 4.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like PP2C PF00481.16 EKG09222.1 - 1.8e-07 30.8 0.1 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EKG09222.1 - 3.1e-07 30.3 1.4 1.2e-05 25.0 1.0 2.7 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EKG09222.1 - 0.00012 21.5 2.0 0.0097 15.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Pkinase PF00069.20 EKG09223.1 - 1e-49 169.0 0.0 1.5e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09223.1 - 5e-20 71.6 0.0 8e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG09223.1 - 7.9e-05 22.5 0.1 0.17 11.5 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EKG09223.1 - 0.0051 16.1 0.2 0.029 13.7 0.0 2.0 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.1 EKG09223.1 - 0.0083 15.1 0.0 0.024 13.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG09223.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 EKG09223.1 - 0.24 9.4 0.0 0.34 8.9 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein SUI1 PF01253.17 EKG09224.1 - 1.5e-21 76.0 0.1 2.7e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EKG09224.1 - 0.012 15.4 0.2 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Met_10 PF02475.11 EKG09225.1 - 6.2e-65 218.5 0.0 7.7e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EKG09225.1 - 0.072 13.1 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Kinesin PF00225.18 EKG09226.1 - 3.4e-113 377.7 0.0 3.4e-113 377.7 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EKG09226.1 - 2.1e-38 131.1 0.0 5.1e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EKG09226.1 - 9.2e-09 35.4 0.1 6e-08 32.8 0.0 2.3 2 0 0 2 2 2 1 PH domain KIF1B PF12423.3 EKG09226.1 - 1.9e-06 27.7 0.6 5.5e-06 26.2 0.4 1.9 1 0 0 1 1 1 1 Kinesin protein 1B Band_7 PF01145.20 EKG09226.1 - 0.022 14.6 4.3 0.088 12.7 3.0 2.0 1 0 0 1 1 1 0 SPFH domain / Band 7 family DUF4358 PF14270.1 EKG09226.1 - 0.16 11.8 11.4 0.01 15.7 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) PH_11 PF15413.1 EKG09226.1 - 0.2 11.8 2.1 1.4 9.2 0.0 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain Hydrophobin PF01185.13 EKG09227.1 - 3.7e-06 27.2 11.4 6.6e-06 26.4 7.9 1.4 1 0 0 1 1 1 1 Fungal hydrophobin HJURP_mid PF12346.3 EKG09227.1 - 0.62 10.2 2.4 11 6.1 0.0 2.1 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat Rad17 PF03215.10 EKG09229.1 - 2.1e-62 211.5 0.0 4.3e-62 210.4 0.0 1.4 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EKG09229.1 - 0.052 13.7 0.0 0.12 12.6 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EKG09229.1 - 0.064 13.0 0.0 0.19 11.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EKG09229.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKG09229.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CBFB_NFYA PF02045.10 EKG09230.1 - 3e-30 104.5 3.8 6.3e-30 103.4 2.6 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF3678 PF12435.3 EKG09231.1 - 0.064 12.8 0.8 5.5 6.6 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3678) Ribosomal_L37 PF08561.5 EKG09232.1 - 4e-19 67.9 0.0 8.1e-19 66.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF3818 PF12825.2 EKG09233.1 - 3.6e-138 459.9 1.9 5.5e-138 459.3 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EKG09233.1 - 1.8e-42 144.1 0.3 4.7e-42 142.8 0.2 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EKG09233.1 - 2.2e-10 40.3 0.0 6.9e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 PX domain DUF3546 PF12066.3 EKG09234.1 - 5.8e-26 90.6 4.1 5.8e-26 90.6 2.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EKG09234.1 - 6.5e-24 83.2 0.2 1.9e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EKG09234.1 - 1.7e-11 44.7 1.2 4.9e-11 43.2 0.8 2.0 1 0 0 1 1 1 1 Arsenite-resistance protein 2 Ribosomal_L6e PF01159.14 EKG09234.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.4 2 1 0 2 2 2 0 Ribosomal protein L6e TspO_MBR PF03073.10 EKG09235.1 - 2.2e-45 153.8 8.1 2.7e-45 153.5 5.6 1.1 1 0 0 1 1 1 1 TspO/MBR family MitoNEET_N PF10660.4 EKG09235.1 - 9.1 6.2 7.8 3.6 7.5 0.1 2.9 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus MFS_1 PF07690.11 EKG09236.1 - 1.4e-08 33.9 14.9 1.5e-08 33.7 10.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CGNR PF11706.3 EKG09237.1 - 0.049 13.1 1.0 0.11 12.0 0.7 1.6 1 0 0 1 1 1 0 CGNR zinc finger Peptidase_M14 PF00246.19 EKG09239.1 - 7.2e-73 245.5 0.1 9.1e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EKG09239.1 - 0.00034 20.2 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase activation peptide TPR_12 PF13424.1 EKG09240.1 - 2.7e-34 116.9 10.5 2.8e-20 72.0 1.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EKG09240.1 - 1.7e-30 103.9 4.7 1.3e-12 47.1 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG09240.1 - 4e-14 51.2 5.0 2e-05 24.0 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKG09240.1 - 5.3e-14 51.6 10.2 4.8e-09 35.7 1.8 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EKG09240.1 - 6.4e-14 50.8 14.1 5e-06 25.8 0.0 3.9 5 0 0 5 5 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKG09240.1 - 1.8e-12 46.1 10.7 0.00018 21.1 0.7 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 EKG09240.1 - 3.5e-11 42.3 0.5 0.0073 16.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKG09240.1 - 8.6e-11 42.2 5.1 8.1e-06 26.3 0.7 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG09240.1 - 1.6e-09 37.5 6.2 0.0041 17.6 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKG09240.1 - 2.6e-09 36.9 7.0 0.035 14.5 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKG09240.1 - 2.9e-09 36.0 10.5 0.0006 19.4 0.4 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG09240.1 - 1.3e-06 28.1 5.7 0.092 12.9 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.4 EKG09240.1 - 5.4e-05 22.6 1.2 0.35 10.2 0.0 3.2 1 1 2 3 3 3 2 26S proteasome subunit RPN7 Apc3 PF12895.2 EKG09240.1 - 5.6e-05 23.2 0.8 0.00013 22.0 0.4 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EKG09240.1 - 0.00012 22.3 6.7 0.017 15.4 1.3 2.7 1 1 2 3 3 3 3 Tetratricopeptide repeat DUF2225 PF09986.4 EKG09240.1 - 0.0012 18.4 0.5 1.1 8.6 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_21 PF09976.4 EKG09240.1 - 0.002 18.0 3.8 0.29 11.0 0.1 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.1 EKG09240.1 - 0.0074 15.4 1.9 0.14 11.2 0.7 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Tcf25 PF04910.9 EKG09240.1 - 0.019 13.9 0.0 1 8.2 0.0 2.2 1 1 1 2 2 2 0 Transcriptional repressor TCF25 TPR_3 PF07720.7 EKG09240.1 - 0.049 13.4 2.9 5.2 6.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat 14-3-3 PF00244.15 EKG09240.1 - 0.058 12.4 0.5 0.97 8.4 0.1 2.4 1 1 2 3 3 3 0 14-3-3 protein MIT PF04212.13 EKG09240.1 - 0.2 11.5 3.0 9.5 6.1 0.4 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PPR PF01535.15 EKG09240.1 - 0.31 11.1 1.8 7.1 6.8 0.0 3.2 4 0 0 4 4 3 0 PPR repeat Sel1 PF08238.7 EKG09240.1 - 0.44 11.2 7.3 4.5 8.0 0.0 3.0 3 0 0 3 3 3 0 Sel1 repeat PS_Dcarbxylase PF02666.10 EKG09242.1 - 2.1e-25 89.2 0.0 2.8e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase CENP-Q PF13094.1 EKG09244.1 - 1.5e-05 25.0 1.5 2.5e-05 24.3 1.1 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CASP_C PF08172.7 EKG09244.1 - 3.2e-05 23.0 6.9 7.4e-05 21.8 4.8 1.6 1 1 0 1 1 1 1 CASP C terminal DUF3109 PF11307.3 EKG09244.1 - 0.00041 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3109) TMF_DNA_bd PF12329.3 EKG09244.1 - 0.001 18.7 8.7 0.0021 17.7 6.0 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Fmp27_WPPW PF10359.4 EKG09244.1 - 0.0014 17.1 0.5 0.0018 16.7 0.3 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain HAP1_N PF04849.8 EKG09244.1 - 0.0077 15.2 3.0 0.014 14.3 2.1 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region GBP_C PF02841.9 EKG09244.1 - 0.011 14.9 6.1 0.016 14.3 4.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF2968 PF11180.3 EKG09244.1 - 0.011 15.1 7.4 0.02 14.2 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIVA PF05103.8 EKG09244.1 - 0.013 15.5 5.9 0.027 14.5 4.1 1.4 1 0 0 1 1 1 0 DivIVA protein Lebercilin PF15619.1 EKG09244.1 - 0.014 14.7 7.0 0.025 14.0 4.9 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.8 EKG09244.1 - 0.018 14.9 3.3 0.043 13.7 1.7 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SseC PF04888.7 EKG09244.1 - 0.023 14.0 1.8 0.035 13.4 1.2 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ArsR PF09824.4 EKG09244.1 - 0.055 12.7 0.1 0.094 12.0 0.1 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator zf-CCHC_4 PF14392.1 EKG09244.1 - 0.068 12.8 9.8 0.26 10.9 1.3 2.5 2 0 0 2 2 2 0 Zinc knuckle ADIP PF11559.3 EKG09244.1 - 0.078 12.8 8.8 0.21 11.4 6.1 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 EKG09244.1 - 0.098 11.0 0.1 0.13 10.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 EKG09244.1 - 0.099 12.1 3.3 2 7.9 3.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) OmpH PF03938.9 EKG09244.1 - 0.11 12.4 4.2 0.2 11.5 2.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EKG09244.1 - 0.13 11.8 4.3 0.22 11.1 3.0 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EKG09244.1 - 0.18 10.7 4.9 0.28 10.1 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF641 PF04859.7 EKG09244.1 - 0.21 11.3 4.3 0.36 10.5 3.0 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.4 EKG09244.1 - 0.24 11.3 6.8 0.42 10.5 4.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Nsp1_C PF05064.8 EKG09244.1 - 0.31 10.7 4.0 0.27 10.8 1.6 1.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF1515 PF07439.6 EKG09244.1 - 0.32 10.8 4.0 0.82 9.5 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF724 PF05266.9 EKG09244.1 - 0.32 10.5 5.3 0.55 9.8 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3498 PF12004.3 EKG09244.1 - 0.35 9.9 8.8 0.25 10.4 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) PhoU PF01895.14 EKG09244.1 - 0.48 10.9 4.5 1.7 9.1 3.1 2.0 1 1 0 1 1 1 0 PhoU domain MbeD_MobD PF04899.7 EKG09244.1 - 0.82 9.6 4.9 3.7 7.5 0.4 2.6 1 1 1 2 2 2 0 MbeD/MobD like GST_C PF00043.20 EKG09245.1 - 5.6e-14 51.9 0.1 9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG09245.1 - 6e-10 38.8 0.0 8.5e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG09245.1 - 7.8e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG09245.1 - 7.8e-06 25.9 0.1 2.2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG09245.1 - 1.5e-05 25.3 0.0 2.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG09245.1 - 0.00034 20.5 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Dimer_Tnp_hAT PF05699.9 EKG09246.1 - 2.8e-13 49.2 0.1 4.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region rve PF00665.21 EKG09250.1 - 4e-17 62.4 0.0 9.8e-17 61.1 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain zf-UBP PF02148.14 EKG09251.1 - 0.045 13.8 0.1 0.092 12.8 0.0 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF4413 PF14372.1 EKG09254.1 - 0.0059 16.5 0.2 0.0093 15.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) p450 PF00067.17 EKG09255.1 - 1.1e-25 90.1 0.0 6.4e-25 87.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EKG09256.1 - 1.5e-34 119.2 37.8 6.2e-34 117.2 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG09256.1 - 1.4e-11 43.6 10.5 1.4e-11 43.6 7.3 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter HNH PF01844.18 EKG09257.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 HNH endonuclease Zn_clus PF00172.13 EKG09259.1 - 9.4e-07 28.6 4.3 1.6e-06 27.9 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPMT PF05724.6 EKG09260.1 - 5.4e-30 104.4 0.0 3.3e-28 98.6 0.0 2.0 1 1 1 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 EKG09260.1 - 0.0018 18.6 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG09260.1 - 0.0083 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG09260.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EKG09260.1 - 0.024 15.0 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EKG09260.1 - 0.033 13.7 0.0 0.077 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EKG09260.1 - 0.048 14.2 0.0 0.079 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 EKG09260.1 - 0.092 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein NmrA PF05368.8 EKG09261.1 - 1.1e-12 47.6 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family YbjQ_1 PF01906.12 EKG09262.1 - 3.9e-11 43.2 0.0 4.4e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding Mrr_cat_2 PF13156.1 EKG09263.1 - 0.096 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease Lactamase_B_2 PF12706.2 EKG09265.1 - 1.5e-26 93.1 0.0 1.9e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG09265.1 - 5.1e-14 52.3 0.0 6.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG09265.1 - 0.0033 17.1 0.9 0.018 14.6 0.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Helitron_like_N PF14214.1 EKG09266.1 - 3.8e-35 121.2 0.0 6.2e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus IF2_assoc PF08364.6 EKG09266.1 - 1.3 9.0 4.7 1.7 8.7 0.2 2.9 2 0 0 2 2 2 0 Bacterial translation initiation factor IF-2 associated region FAD_binding_8 PF08022.7 EKG09267.1 - 2.5e-22 78.7 0.0 8.4e-22 77.0 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EKG09267.1 - 1.1e-19 70.9 0.0 1.8e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EKG09267.1 - 2.9e-16 59.7 11.0 6.3e-16 58.5 7.6 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EKG09267.1 - 0.00024 21.1 0.0 0.0006 19.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain LrgA PF03788.9 EKG09267.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 LrgA family Curlin_rpt PF07012.7 EKG09267.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Curlin associated repeat Dimer_Tnp_hAT PF05699.9 EKG09269.1 - 2.8e-15 55.7 0.1 6.4e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EKG09269.1 - 0.002 18.1 0.7 0.0046 16.8 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Ribosomal_S3Ae PF01015.13 EKG09269.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal S3Ae family RVT_2 PF07727.9 EKG09276.1 - 1.2e-26 93.2 0.1 2.8e-26 91.9 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 EKG09276.1 - 0.013 14.8 0.0 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Attacin_C PF03769.10 EKG09276.1 - 0.024 14.7 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Attacin, C-terminal region RVT_2 PF07727.9 EKG09277.1 - 8.3e-08 31.4 0.1 1.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 EKG09277.1 - 0.02 14.4 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain rve PF00665.21 EKG09277.1 - 0.053 13.6 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Integrase core domain DUF309 PF03745.9 EKG09279.1 - 0.0075 15.7 0.0 0.54 9.7 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF309) DUF3723 PF12520.3 EKG09281.1 - 1.7e-24 86.2 0.0 2e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) zf-RING_5 PF14634.1 EKG09282.1 - 0.08 12.6 8.6 0.076 12.7 2.8 2.5 2 0 0 2 2 2 0 zinc-RING finger domain FYVE PF01363.16 EKG09282.1 - 0.36 10.7 4.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger CK_II_beta PF01214.13 EKG09282.1 - 1.7 8.1 4.5 6.5 6.2 0.2 2.6 2 1 1 3 3 3 0 Casein kinase II regulatory subunit zf-C3HC4_2 PF13923.1 EKG09282.1 - 4.8 7.2 9.0 1.5 8.9 3.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAD_binding_8 PF08022.7 EKG09285.1 - 1.8e-17 63.1 0.0 3.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EKG09285.1 - 2.1e-16 60.1 0.0 1.8e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EKG09285.1 - 0.0017 18.9 0.1 0.016 15.7 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EKG09285.1 - 0.0065 16.5 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FixQ PF05545.6 EKG09285.1 - 0.1 12.2 0.0 0.75 9.4 0.0 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4380 PF14315.1 EKG09289.1 - 0.095 11.8 0.2 1.7 7.7 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4380) zf-CCHC PF00098.18 EKG09292.1 - 0.00084 19.1 3.7 0.00084 19.1 2.6 2.3 3 0 0 3 3 3 1 Zinc knuckle AT_hook PF02178.14 EKG09292.1 - 1.1 9.1 4.1 3.4 7.6 2.8 1.8 1 0 0 1 1 1 0 AT hook motif Exo_endo_phos_2 PF14529.1 EKG09293.1 - 2.4e-21 75.5 0.3 9.3e-21 73.6 0.0 2.1 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EKG09293.1 - 8.3e-11 42.2 1.4 1.2e-10 41.7 0.9 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 EKG09293.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TBPIP PF07106.8 EKG09296.1 - 0.00099 18.6 5.4 0.089 12.3 0.1 2.3 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Uds1 PF15456.1 EKG09296.1 - 0.0018 18.2 3.3 0.004 17.1 2.3 1.5 1 1 0 1 1 1 1 Up-regulated During Septation DUF4140 PF13600.1 EKG09296.1 - 0.0029 18.0 2.9 0.87 10.0 0.0 2.2 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 EKG09296.1 - 0.0031 17.2 3.0 0.0045 16.6 2.1 1.2 1 0 0 1 1 1 1 Mnd1 family DUF4519 PF15012.1 EKG09296.1 - 0.0042 16.9 2.7 0.0088 15.9 1.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) AAA_23 PF13476.1 EKG09296.1 - 0.016 15.5 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EKG09296.1 - 0.021 13.5 3.0 0.97 8.0 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Lge1 PF11488.3 EKG09296.1 - 0.034 14.3 1.0 0.32 11.2 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Seryl_tRNA_N PF02403.17 EKG09296.1 - 0.095 12.7 6.0 1.5 8.8 0.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Bap31 PF05529.7 EKG09296.1 - 0.19 11.1 2.3 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like NPV_P10 PF05531.7 EKG09296.1 - 0.22 11.7 2.4 12 6.1 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HemX PF04375.9 EKG09296.1 - 0.39 9.2 3.9 6.6 5.2 0.7 2.1 2 0 0 2 2 2 0 HemX DUF812 PF05667.6 EKG09296.1 - 0.49 8.8 8.6 3.9 5.8 6.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.4 EKG09296.1 - 1.3 9.1 5.7 2.2 8.4 0.9 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glyco_hydro_18 PF00704.23 EKG09297.1 - 3.1e-09 36.7 0.3 8.9e-07 28.6 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Spidroin_MaSp PF11260.3 EKG09304.1 - 0.17 11.9 2.3 2.4 8.2 0.2 2.3 1 1 1 2 2 2 0 Major ampullate spidroin 1 and 2 rve PF00665.21 EKG09305.1 - 3.3e-05 23.9 0.0 9.5e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Allexi_40kDa PF05549.6 EKG09308.1 - 0.00058 19.2 1.0 0.0013 18.1 0.7 1.5 1 0 0 1 1 1 1 Allexivirus 40kDa protein Serine_rich PF08824.5 EKG09308.1 - 0.022 14.4 0.8 0.022 14.4 0.6 1.4 2 0 0 2 2 2 0 Serine rich protein interaction domain DUF4600 PF15372.1 EKG09308.1 - 0.027 14.6 1.9 0.027 14.6 1.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) NPV_P10 PF05531.7 EKG09308.1 - 0.057 13.6 1.4 1.3 9.2 0.5 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 EKG09308.1 - 0.065 11.6 1.7 0.085 11.2 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Reo_sigmaC PF04582.7 EKG09308.1 - 0.092 11.9 1.0 0.13 11.4 0.7 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PilJ PF13675.1 EKG09308.1 - 0.17 12.1 3.3 0.21 11.9 1.3 1.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term V-SNARE PF05008.10 EKG09308.1 - 0.19 11.8 2.7 0.21 11.7 0.2 2.3 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TBPIP PF07106.8 EKG09308.1 - 0.4 10.1 4.5 0.3 10.6 2.2 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4407 PF14362.1 EKG09308.1 - 0.45 9.4 6.2 0.61 8.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.1 EKG09308.1 - 0.61 10.0 10.8 0.03 14.2 2.1 2.5 2 1 1 3 3 2 0 FlxA-like protein MtrG PF04210.8 EKG09308.1 - 0.77 9.4 5.6 0.56 9.9 0.1 2.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Mitofilin PF09731.4 EKG09308.1 - 0.82 8.2 21.1 2.7 6.5 14.6 1.7 1 1 0 1 1 1 0 Mitochondrial inner membrane protein HALZ PF02183.13 EKG09308.1 - 0.97 9.2 5.8 0.97 9.2 0.1 3.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper ATG16 PF08614.6 EKG09308.1 - 1.2 8.9 14.1 0.32 10.7 7.4 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EKG09308.1 - 1.3 8.5 19.0 3.5 7.1 13.2 1.7 1 1 0 1 1 1 0 IncA protein AATF-Che1 PF13339.1 EKG09308.1 - 3 8.0 8.8 0.43 10.7 2.2 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF605 PF04652.11 EKG09308.1 - 4.5 6.5 19.2 6.1 6.1 13.3 1.1 1 0 0 1 1 1 0 Vta1 like SlyX PF04102.7 EKG09308.1 - 6.1 7.2 8.8 2.6 8.4 0.4 3.1 2 1 1 3 3 2 0 SlyX DUF4140 PF13600.1 EKG09308.1 - 6.3 7.3 9.3 2 8.9 0.9 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Host_attach PF10116.4 EKG09309.1 - 0.0026 17.9 0.5 0.087 13.0 0.0 2.3 2 0 0 2 2 2 1 Protein required for attachment to host cells DUF900 PF05990.7 EKG09309.1 - 0.0029 16.9 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EKG09309.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EKG09309.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain LCAT PF02450.10 EKG09309.1 - 0.035 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3530 PF12048.3 EKG09309.1 - 0.035 13.0 0.3 0.062 12.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) PIF1 PF05970.9 EKG09310.1 - 0.00076 18.5 0.0 0.00091 18.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Herpes_Helicase PF02689.9 EKG09310.1 - 0.01 13.5 0.0 0.014 13.1 0.0 1.1 1 0 0 1 1 1 0 Helicase UvrD_C_2 PF13538.1 EKG09310.1 - 0.017 15.2 0.0 0.049 13.7 0.0 1.9 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EKG09311.1 - 4.3e-13 48.9 0.0 5.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EKG09311.1 - 2.9e-09 36.8 0.0 3.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG09311.1 - 3.5e-05 23.4 0.0 6.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EKG09311.1 - 0.00021 21.4 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EKG09311.1 - 0.076 13.3 0.1 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EKG09311.1 - 0.12 13.1 0.0 0.19 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EKG09311.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 PriCT_2 PF08707.6 EKG09312.1 - 0.013 15.3 0.2 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Helitron_like_N PF14214.1 EKG09313.1 - 0.00013 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus zf-RING_3 PF14369.1 EKG09314.1 - 2.5 8.1 10.5 4.1 7.4 1.6 3.3 3 0 0 3 3 3 0 zinc-finger PBP1_TM PF14812.1 EKG09315.1 - 0.32 11.3 3.7 0.8 10.0 2.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chromo PF00385.19 EKG09316.1 - 0.32 10.7 10.1 0.75 9.5 0.6 3.2 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain SH3_9 PF14604.1 EKG09317.1 - 7e-08 31.9 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG09317.1 - 2e-07 30.2 0.0 3.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EKG09317.1 - 2.7e-06 26.7 0.0 4.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Rifin_STEVOR PF02009.11 EKG09317.1 - 0.0014 18.3 0.1 0.0023 17.6 0.1 1.3 1 0 0 1 1 1 1 Rifin/stevor family EphA2_TM PF14575.1 EKG09317.1 - 0.098 13.0 0.1 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DcuC PF03606.10 EKG09317.1 - 0.1 10.8 0.7 0.14 10.3 0.5 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier MSC PF09402.5 EKG09317.1 - 0.36 9.5 0.0 0.53 8.9 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain RasGEF PF00617.14 EKG09319.1 - 2e-45 154.8 0.0 3.1e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKG09319.1 - 3.4e-13 49.5 0.3 8e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF3270 PF11674.3 EKG09321.1 - 0.15 12.0 0.4 0.15 12.0 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3270) Cyt_c_ox_IV PF12270.3 EKG09321.1 - 3 7.6 11.0 0.15 11.8 2.0 2.8 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IV Retrotrans_gag PF03732.12 EKG09322.1 - 7.6e-10 38.7 0.4 7.6e-10 38.7 0.3 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF972 PF06156.8 EKG09322.1 - 0.0036 17.6 0.3 0.03 14.6 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF972) DivIC PF04977.10 EKG09322.1 - 0.05 13.0 1.2 0.13 11.7 0.8 1.6 1 0 0 1 1 1 0 Septum formation initiator PspA_IM30 PF04012.7 EKG09322.1 - 0.13 11.6 0.3 0.13 11.6 0.2 1.7 2 0 0 2 2 2 0 PspA/IM30 family Nnf1 PF03980.9 EKG09322.1 - 0.25 11.3 1.8 0.56 10.2 0.5 2.0 2 0 0 2 2 2 0 Nnf1 bZIP_2 PF07716.10 EKG09322.1 - 0.42 10.4 2.7 0.96 9.3 1.9 1.7 1 0 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EKG09322.1 - 0.62 9.6 2.8 1.3 8.5 0.8 1.9 2 0 0 2 2 2 0 IncA protein Mcp5_PH PF12814.2 EKG09324.1 - 6.2e-45 152.0 0.0 1.6e-44 150.7 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_1 PF00515.23 EKG09325.1 - 1.1e-11 43.8 3.0 0.00074 19.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKG09325.1 - 6.6e-09 35.0 3.1 0.096 12.6 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG09325.1 - 8.8e-09 34.8 7.7 7.9e-05 22.2 1.8 3.4 2 1 0 3 3 3 2 TPR repeat Apc3 PF12895.2 EKG09325.1 - 9.7e-05 22.4 1.5 0.00018 21.5 0.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EKG09325.1 - 0.00019 21.9 0.6 0.034 14.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG09325.1 - 0.00025 21.3 1.8 0.0016 18.7 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKG09325.1 - 0.0029 17.4 2.7 1.8 8.5 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3808 PF10300.4 EKG09325.1 - 0.0048 15.5 0.6 0.0067 15.0 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.1 EKG09325.1 - 0.012 15.3 1.0 7.1 6.6 0.0 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG09325.1 - 0.021 15.4 4.0 0.57 10.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 EKG09325.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.3 3 0 0 3 3 3 0 Poxvirus T4 protein, N terminus HMG-CoA_red PF00368.13 EKG09326.1 - 0.19 10.3 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase SHMT PF00464.14 EKG09327.1 - 5.9e-177 587.9 0.0 6.8e-177 587.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EKG09327.1 - 0.0036 16.0 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF1517 PF07466.6 EKG09328.1 - 0.019 13.9 1.3 0.026 13.5 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Mid2 PF04478.7 EKG09328.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2029 PF09594.5 EKG09328.1 - 0.16 11.4 1.6 0.24 10.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) OMP_b-brl PF13505.1 EKG09328.1 - 4.3 7.2 7.6 1.2 9.0 2.4 1.9 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain polyprenyl_synt PF00348.12 EKG09329.1 - 3.7e-52 176.7 0.0 5.2e-49 166.4 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EKG09329.1 - 0.027 13.9 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.3 EKG09330.1 - 3.2e-25 88.4 0.0 4.6e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4500 PF14937.1 EKG09330.1 - 0.035 13.9 0.1 0.075 12.8 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4500) DUF3487 PF11990.3 EKG09330.1 - 0.2 11.0 1.2 0.35 10.2 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) HAMP PF00672.20 EKG09330.1 - 0.79 9.9 3.0 2.4 8.3 2.1 2.0 1 1 0 1 1 1 0 HAMP domain MOZ_SAS PF01853.13 EKG09331.1 - 9.7e-65 217.3 0.0 1.4e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family BTB PF00651.26 EKG09332.1 - 1.5e-09 37.7 0.0 4.6e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain UL73_N PF12522.3 EKG09332.1 - 0.03 13.8 7.0 0.063 12.8 4.8 1.5 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal BRCT PF00533.21 EKG09333.1 - 0.0087 16.1 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKG09333.1 - 0.038 13.8 0.1 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Zn_clus PF00172.13 EKG09335.1 - 2.6e-09 36.8 8.9 2.6e-09 36.8 6.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MxiH PF09392.5 EKG09336.1 - 1.4 9.5 4.3 3 8.4 3.0 1.7 1 1 0 1 1 1 0 Type III secretion needle MxiH like DEAD PF00270.24 EKG09337.1 - 3.8e-48 163.1 0.0 4.6e-47 159.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG09337.1 - 1.2e-27 95.5 0.0 2.1e-26 91.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EKG09337.1 - 0.011 14.2 0.0 0.011 14.2 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EKG09337.1 - 0.1 11.6 0.0 0.1 11.6 0.0 4.8 3 2 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit DUF2256 PF10013.4 EKG09338.1 - 0.00059 19.5 1.2 0.0021 17.7 0.8 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Ecl1 PF12855.2 EKG09338.1 - 0.0037 16.5 0.3 0.0076 15.5 0.2 1.5 1 0 0 1 1 1 1 Life-span regulatory factor Zn_ribbon_2 PF12674.2 EKG09338.1 - 0.0041 17.4 1.7 0.0051 17.1 0.1 2.0 2 0 0 2 2 2 1 Putative zinc ribbon domain Pkinase PF00069.20 EKG09339.1 - 4.6e-74 248.8 0.0 6.1e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09339.1 - 3.8e-31 108.0 0.0 5e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG09339.1 - 0.0011 17.9 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG09339.1 - 0.002 17.2 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG09339.1 - 0.0084 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EKG09339.1 - 0.027 13.2 0.1 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Evr1_Alr PF04777.8 EKG09340.1 - 1.3e-27 95.4 2.3 1.8e-27 95.0 1.6 1.2 1 0 0 1 1 1 1 Erv1 / Alr family HEM4 PF02602.10 EKG09341.1 - 2.5e-38 131.6 0.0 8.1e-38 129.9 0.0 1.8 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Mad3_BUB1_I PF08311.7 EKG09345.1 - 7.8e-44 148.4 0.2 1.6e-43 147.5 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EKG09345.1 - 2.7e-15 56.2 0.0 8.2e-15 54.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09345.1 - 1.3e-06 27.7 0.0 2.1e-05 23.7 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EKG09345.1 - 2.9e-06 27.0 0.1 0.00026 20.8 0.0 2.6 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 APH PF01636.18 EKG09345.1 - 0.00048 19.9 0.6 0.34 10.5 0.1 2.7 2 0 0 2 2 2 2 Phosphotransferase enzyme family Lectin_leg-like PF03388.8 EKG09346.1 - 5.3e-21 74.8 0.1 8e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family NPV_P10 PF05531.7 EKG09346.1 - 0.0069 16.6 1.3 0.85 9.9 0.1 2.4 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EKG09346.1 - 0.0087 16.2 0.9 0.0087 16.2 0.6 1.5 2 0 0 2 2 2 1 Syntaxin Med30 PF11315.3 EKG09346.1 - 0.0093 16.1 0.2 0.022 14.9 0.1 1.6 1 1 0 1 1 1 1 Mediator complex subunit 30 Baculo_PEP_C PF04513.7 EKG09346.1 - 0.035 13.9 1.2 0.18 11.6 0.0 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PAT1 PF09770.4 EKG09346.1 - 0.036 12.3 9.7 0.045 11.9 6.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EMP24_GP25L PF01105.19 EKG09346.1 - 0.098 12.3 7.1 0.043 13.5 1.5 2.5 2 2 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Laminin_II PF06009.7 EKG09346.1 - 0.66 9.7 3.7 18 5.0 0.8 2.1 1 1 0 2 2 2 0 Laminin Domain II Fungal_trans PF04082.13 EKG09347.1 - 4.4e-08 32.3 0.0 1e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ric8 PF10165.4 EKG09347.1 - 0.018 13.8 0.5 0.027 13.2 0.3 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn PCI PF01399.22 EKG09348.1 - 0.031 14.5 0.0 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 PCI domain Apc3 PF12895.2 EKG09348.1 - 0.053 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EKG09348.1 - 0.097 13.3 0.1 0.31 11.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyridox_oxidase PF01243.15 EKG09349.1 - 2.5e-09 37.0 0.0 4.1e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Disaggr_repeat PF06848.6 EKG09351.1 - 0.13 11.6 0.1 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Disaggregatase related repeat DDHD PF02862.12 EKG09352.1 - 1.4e-70 237.6 0.7 1.4e-70 237.6 0.5 3.9 2 2 0 2 2 2 1 DDHD domain LCAT PF02450.10 EKG09352.1 - 0.041 12.8 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 EKG09352.1 - 0.047 13.4 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 EKG09352.1 - 0.074 12.3 0.0 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative serine esterase (DUF676) GMC_oxred_N PF00732.14 EKG09353.1 - 1.5e-62 211.4 0.0 2e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG09353.1 - 4.6e-36 124.2 0.0 1.3e-35 122.8 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase DUF2183 PF09949.4 EKG09354.1 - 1.4e-19 69.9 0.2 3.3e-19 68.6 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) CoA_trans PF01144.18 EKG09356.1 - 5e-107 356.0 0.4 1.4e-65 220.4 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Fungal_trans PF04082.13 EKG09357.1 - 1.1e-18 67.1 4.6 1.1e-18 67.1 3.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG09357.1 - 1.1e-06 28.4 8.8 2.7e-06 27.1 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Es2 PF09751.4 EKG09357.1 - 0.0073 15.7 0.3 0.015 14.7 0.2 1.5 1 0 0 1 1 1 1 Nuclear protein Es2 MFS_1 PF07690.11 EKG09358.1 - 1.2e-43 149.2 30.0 1.2e-43 149.2 20.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG09358.1 - 2.4e-10 39.2 1.6 3.9e-10 38.5 1.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG09358.1 - 1.5e-07 30.3 23.2 4.5e-07 28.8 16.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EKG09358.1 - 0.034 12.2 4.0 0.24 9.4 0.2 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RRM_1 PF00076.17 EKG09360.1 - 9.3e-28 95.6 0.0 4e-19 68.0 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG09360.1 - 2.4e-22 78.6 0.0 4.9e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG09360.1 - 2.4e-17 62.5 0.0 4.7e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKG09360.1 - 0.007 16.1 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Mito_carr PF00153.22 EKG09361.1 - 7.1e-23 80.1 0.5 2.9e-11 42.9 0.1 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein Pyr_redox_3 PF13738.1 EKG09362.1 - 5.4e-22 78.8 0.0 3.3e-21 76.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG09362.1 - 2.1e-20 72.4 0.0 1.4e-19 69.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EKG09362.1 - 7.6e-12 45.5 0.0 1.1e-09 38.4 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG09362.1 - 5e-10 38.8 0.0 5e-08 32.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EKG09362.1 - 1e-06 28.6 2.0 2.2e-06 27.6 0.1 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG09362.1 - 3.5e-05 24.1 3.1 0.11 12.8 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG09362.1 - 9.3e-05 22.5 0.1 0.085 12.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EKG09362.1 - 0.00012 21.1 1.4 0.00012 21.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG09362.1 - 0.0056 16.4 1.8 0.48 10.1 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF3506 PF12014.3 EKG09362.1 - 0.013 15.3 0.1 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) FAD_binding_2 PF00890.19 EKG09362.1 - 0.048 12.5 3.6 0.026 13.3 0.8 1.7 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EKG09362.1 - 0.06 13.0 0.7 0.12 12.0 0.4 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EKG09362.1 - 0.081 13.1 0.0 0.57 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EKG09362.1 - 0.17 10.3 1.0 1.4 7.2 0.1 2.4 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EKG09362.1 - 1.7 7.4 3.1 2.3 7.0 0.5 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A PEPCK_ATP PF01293.15 EKG09363.1 - 3e-217 721.7 0.0 3.5e-217 721.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 EKG09363.1 - 0.085 12.7 0.4 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EKG09363.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RVT_1 PF00078.22 EKG09366.1 - 3.9e-29 101.5 0.0 7.6e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EKG09366.1 - 3e-22 78.4 0.1 8.2e-22 77.0 0.0 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EKG09366.1 - 5.5e-19 68.8 0.2 1.7e-18 67.2 0.1 1.9 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EKG09366.1 - 3.9e-12 46.6 1.7 6.3e-12 45.9 1.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCHC PF00098.18 EKG09367.1 - 0.0022 17.8 3.4 0.0022 17.8 2.4 2.2 2 0 0 2 2 2 1 Zinc knuckle Histone PF00125.19 EKG09368.1 - 1.1e-22 79.9 0.1 1.3e-22 79.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKG09368.1 - 0.00031 20.7 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-CCCH PF00642.19 EKG09369.1 - 0.00014 21.4 3.2 0.00014 21.4 2.2 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BTB PF00651.26 EKG09370.1 - 3.3e-14 52.8 0.0 6.4e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Dimer_Tnp_hAT PF05699.9 EKG09372.1 - 1.3e-16 59.9 0.0 2.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3449 PF11931.3 EKG09372.1 - 0.0052 16.3 0.7 0.0071 15.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Calc_CGRP_IAPP PF00214.14 EKG09372.1 - 0.098 12.7 0.3 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Dimer_Tnp_hAT PF05699.9 EKG09374.1 - 4.5e-12 45.4 0.0 5.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ank_2 PF12796.2 EKG09375.1 - 2.5e-130 425.1 1.5 6.7e-17 61.6 0.0 8.1 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EKG09375.1 - 8.1e-84 271.5 12.9 2.8e-08 33.1 0.0 14.2 14 0 0 14 14 14 14 Ankyrin repeat Ank_4 PF13637.1 EKG09375.1 - 6e-80 262.3 24.5 1.4e-10 41.4 0.1 12.0 1 1 12 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG09375.1 - 2.7e-77 253.0 32.4 1.4e-13 50.5 0.0 9.8 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG09375.1 - 2e-68 219.4 0.2 3.1e-05 23.8 0.0 14.2 14 0 0 14 14 14 13 Ankyrin repeat NMT1 PF09084.6 EKG09375.1 - 0.0039 16.8 0.0 8.1 5.9 0.0 4.4 2 1 1 4 4 4 1 NMT1/THI5 like DDE_3 PF13358.1 EKG09377.1 - 6.9e-22 77.7 0.0 1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 EKG09377.1 - 2.7e-06 26.7 0.0 4.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix DDE_1 PF03184.14 EKG09377.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EKG09377.1 - 0.051 13.6 0.1 0.22 11.6 0.0 2.0 2 1 1 3 3 3 0 Integrase core domain AAA_30 PF13604.1 EKG09377.1 - 0.13 11.8 0.0 4.9 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DDE_Tnp_1_7 PF13843.1 EKG09378.1 - 1.5e-12 47.2 0.3 2e-12 46.8 0.2 1.1 1 0 0 1 1 1 1 Transposase IS4 Dimer_Tnp_hAT PF05699.9 EKG09380.1 - 1.9e-12 46.6 0.1 3.9e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 EKG09380.1 - 0.025 14.3 0.1 0.068 12.9 0.1 1.8 1 0 0 1 1 1 0 BED zinc finger HLH PF00010.21 EKG09381.1 - 7.4e-09 35.1 0.6 3.1e-08 33.2 0.0 2.3 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain ApbE PF02424.10 EKG09381.1 - 0.048 12.9 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 ApbE family ORC6 PF05460.8 EKG09381.1 - 0.27 10.3 5.8 0.33 10.0 4.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) 2OG-FeII_Oxy PF03171.15 EKG09383.1 - 2.5e-13 50.1 0.0 5.3e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Dimer_Tnp_hAT PF05699.9 EKG09385.1 - 3.7e-17 61.7 0.8 6.7e-17 60.8 0.1 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region ArfGap PF01412.13 EKG09387.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DDE_1 PF03184.14 EKG09388.1 - 1.8e-30 105.6 0.1 5.2e-25 87.8 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_1 PF03184.14 EKG09389.1 - 4.2e-07 29.3 0.2 1.1e-06 28.0 0.1 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EKG09389.1 - 1.7e-06 27.7 0.0 4.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Kisspeptin PF15152.1 EKG09389.1 - 0.088 13.5 1.3 1.1 9.9 0.0 2.8 2 1 0 2 2 2 0 Kisspeptin HTH_psq PF05225.11 EKG09389.1 - 0.24 10.9 0.1 0.24 10.9 0.1 1.8 2 0 0 2 2 2 0 helix-turn-helix, Psq domain zf-CCHC PF00098.18 EKG09389.1 - 3.3 7.8 11.3 0.4 10.7 3.5 2.3 2 0 0 2 2 2 0 Zinc knuckle bZIP_1 PF00170.16 EKG09390.1 - 1.8e-11 43.8 4.3 3.7e-11 42.7 3.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG09390.1 - 3.1e-08 33.3 1.7 7.4e-08 32.1 1.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DUF1465 PF07323.7 EKG09390.1 - 0.00016 21.3 0.0 0.00076 19.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1465) bZIP_Maf PF03131.12 EKG09390.1 - 0.0021 18.3 1.6 0.0047 17.1 1.1 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor DivIC PF04977.10 EKG09390.1 - 0.03 13.8 0.6 0.079 12.4 0.4 1.6 1 0 0 1 1 1 0 Septum formation initiator Tropomyosin_1 PF12718.2 EKG09390.1 - 0.035 13.9 1.9 0.075 12.8 1.3 1.5 1 0 0 1 1 1 0 Tropomyosin like Tropomyosin_1 PF12718.2 EKG09393.1 - 0.0012 18.7 8.1 0.0022 17.8 5.6 1.4 1 0 0 1 1 1 1 Tropomyosin like CENP-Q PF13094.1 EKG09393.1 - 0.0019 18.2 6.7 0.0037 17.3 4.6 1.4 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit HOOK PF05622.7 EKG09393.1 - 0.0026 15.6 4.9 0.0035 15.2 3.4 1.1 1 0 0 1 1 1 1 HOOK protein Filament PF00038.16 EKG09393.1 - 0.0036 16.8 4.9 0.011 15.2 3.4 1.7 2 0 0 2 2 2 1 Intermediate filament protein IncA PF04156.9 EKG09393.1 - 0.0036 16.9 4.8 0.0055 16.3 3.4 1.2 1 0 0 1 1 1 1 IncA protein DUF1843 PF08898.5 EKG09393.1 - 0.013 15.5 1.4 0.033 14.2 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Laminin_I PF06008.9 EKG09393.1 - 0.015 14.6 3.3 0.022 14.0 2.3 1.2 1 0 0 1 1 1 0 Laminin Domain I TMF_TATA_bd PF12325.3 EKG09393.1 - 0.026 14.2 5.1 0.048 13.3 3.5 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF848 PF05852.6 EKG09393.1 - 0.034 14.0 2.9 0.074 12.8 2.0 1.6 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) BLOC1_2 PF10046.4 EKG09393.1 - 0.044 13.9 5.7 0.089 12.9 4.0 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3839 PF12943.2 EKG09393.1 - 0.05 12.7 0.1 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) IFT57 PF10498.4 EKG09393.1 - 0.057 12.1 4.3 0.08 11.6 3.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PspA_IM30 PF04012.7 EKG09393.1 - 0.059 12.7 4.3 0.1 11.9 3.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family Jnk-SapK_ap_N PF09744.4 EKG09393.1 - 0.06 13.3 3.9 0.1 12.5 2.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3573 PF12097.3 EKG09393.1 - 0.089 11.3 0.2 0.12 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 EKG09393.1 - 0.11 10.2 0.2 0.12 10.1 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EKG09393.1 - 0.12 11.9 3.2 0.22 11.0 2.2 1.5 1 0 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.6 EKG09393.1 - 0.34 9.5 2.3 0.51 8.9 1.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Trehalase PF01204.13 EKG09393.1 - 0.35 9.4 1.5 0.48 8.9 1.1 1.2 1 0 0 1 1 1 0 Trehalase DUF972 PF06156.8 EKG09393.1 - 0.61 10.4 4.0 1.7 8.9 2.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4404 PF14357.1 EKG09393.1 - 0.71 10.3 5.5 0.32 11.4 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Snapin_Pallidin PF14712.1 EKG09393.1 - 1.2 9.4 8.8 0.19 12.0 3.0 1.9 2 1 0 2 2 2 0 Snapin/Pallidin DUF2205 PF10224.4 EKG09393.1 - 1.6 8.3 6.4 2.8 7.5 1.9 2.4 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) HTH_Tnp_Tc5 PF03221.11 EKG09395.1 - 0.0048 16.6 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG09395.1 - 0.025 14.1 0.2 0.04 13.4 0.2 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain LysM PF01476.15 EKG09396.1 - 1.5e-08 34.3 0.0 0.0046 16.8 0.0 3.3 3 0 0 3 3 3 3 LysM domain Sigma70_r4 PF04545.11 EKG09396.1 - 0.17 11.2 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 PAGK PF15284.1 EKG09396.1 - 0.23 11.2 1.8 0.42 10.3 1.3 1.4 1 0 0 1 1 1 0 Phage-encoded virulence factor PD40 PF07676.7 EKG09397.1 - 2.6e-28 97.1 24.7 0.00033 20.2 0.5 9.7 9 0 0 9 9 9 8 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EKG09397.1 - 4.7e-08 31.9 5.2 0.41 9.1 0.0 6.2 2 2 4 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DDE_1 PF03184.14 EKG09398.1 - 4.8e-11 42.2 0.0 6.5e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EKG09398.1 - 0.00034 20.3 0.0 0.00097 18.9 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2 PF00096.21 EKG09399.1 - 0.16 12.3 8.8 0.45 10.9 1.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Dioxygenase_C PF00775.16 EKG09400.1 - 1.7e-08 33.9 0.0 3.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Dioxygenase HALZ PF02183.13 EKG09403.1 - 0.026 14.2 0.5 0.043 13.5 0.3 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper TFIID-31kDa PF02291.10 EKG09403.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RVT_1 PF00078.22 EKG09404.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TFIIB PF00382.14 EKG09404.1 - 0.09 12.6 0.2 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Dimer_Tnp_hAT PF05699.9 EKG09406.1 - 2.4e-05 23.8 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TraF PF13728.1 EKG09407.1 - 0.0014 18.1 0.4 0.0014 18.1 0.3 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Toxin_41 PF15521.1 EKG09407.1 - 0.087 11.9 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Putative toxin 41 HSDR_N_2 PF13588.1 EKG09409.1 - 0.065 13.0 0.0 8.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) XRN_N PF03159.13 EKG09410.1 - 0.13 11.6 1.6 0.15 11.4 1.1 1.0 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Vfa1 PF08432.5 EKG09410.1 - 0.16 11.9 5.0 0.19 11.7 3.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1777 PF08648.7 EKG09410.1 - 0.24 11.1 9.5 0.24 11.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) NARP1 PF12569.3 EKG09410.1 - 0.36 9.5 7.2 0.35 9.5 5.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3306 PF11748.3 EKG09410.1 - 0.39 11.3 6.2 0.51 11.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) ARGLU PF15346.1 EKG09410.1 - 0.48 10.1 24.3 0.56 9.9 16.9 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 CAF-1_p150 PF11600.3 EKG09410.1 - 0.61 9.4 23.2 0.82 9.0 16.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mnd1 PF03962.10 EKG09410.1 - 0.68 9.5 12.1 0.76 9.4 8.4 1.1 1 0 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 EKG09410.1 - 0.92 9.8 4.8 1.2 9.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Peptidase_S49_N PF08496.5 EKG09410.1 - 0.97 9.2 5.8 1.1 9.0 4.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tom37_C PF11801.3 EKG09410.1 - 2.7 7.8 6.3 3.1 7.6 4.3 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain HR1 PF02185.11 EKG09410.1 - 3.6 7.3 15.2 5.1 6.9 10.3 1.4 1 1 0 1 1 1 0 Hr1 repeat DDRGK PF09756.4 EKG09410.1 - 3.9 6.8 16.3 5 6.4 11.3 1.2 1 0 0 1 1 1 0 DDRGK domain DUF3987 PF13148.1 EKG09410.1 - 3.9 5.9 9.5 3.9 5.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Caldesmon PF02029.10 EKG09410.1 - 4.5 5.5 18.0 4.9 5.4 12.5 1.0 1 0 0 1 1 1 0 Caldesmon DUF4404 PF14357.1 EKG09410.1 - 4.9 7.6 10.6 6.7 7.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) OmpH PF03938.9 EKG09410.1 - 6.1 6.7 14.6 7 6.5 10.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1840 PF08895.6 EKG09410.1 - 7 6.7 7.5 11 6.0 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Tetraspannin PF00335.15 EKG09411.1 - 0.091 12.0 0.2 0.13 11.5 0.1 1.3 1 1 0 1 1 1 0 Tetraspanin family HlyIII PF03006.15 EKG09411.1 - 0.13 11.6 1.6 0.17 11.3 1.1 1.1 1 0 0 1 1 1 0 Haemolysin-III related zf-CCHC PF00098.18 EKG09412.1 - 0.0016 18.2 3.4 0.0016 18.2 2.4 2.3 2 0 0 2 2 2 1 Zinc knuckle Dimer_Tnp_hAT PF05699.9 EKG09413.1 - 5.9e-16 57.8 0.0 1.4e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF970 PF06153.6 EKG09413.1 - 0.018 15.0 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF970) Methyltrans_RNA PF04452.9 EKG09414.1 - 0.0021 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase Pyr_redox_3 PF13738.1 EKG09415.1 - 1e-26 94.2 0.0 3.7e-25 89.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG09415.1 - 1.6e-06 28.0 0.1 6.7e-06 26.0 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EKG09415.1 - 5.8e-06 25.4 0.0 8.9e-05 21.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EKG09415.1 - 1.9e-05 23.1 0.0 0.00042 18.6 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EKG09415.1 - 0.00016 21.4 0.2 0.015 15.0 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EKG09415.1 - 0.00028 21.0 0.0 0.037 14.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EKG09415.1 - 0.00037 20.4 0.0 0.6 9.9 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EKG09415.1 - 0.0062 15.6 0.0 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG09415.1 - 0.072 13.5 0.1 3.4 8.1 0.1 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RVT_2 PF07727.9 EKG09416.1 - 2e-47 161.2 0.1 3.5e-47 160.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EKG09416.1 - 2.8e-09 37.1 0.0 1.1e-08 35.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EKG09416.1 - 0.011 15.3 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain Acetyltransf_1 PF00583.19 EKG09417.1 - 9.1e-08 32.0 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG09417.1 - 0.0058 16.7 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG09417.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.1 EKG09417.1 - 0.049 14.1 0.0 6.2 7.4 0.0 2.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EKG09417.1 - 0.16 11.9 0.4 1.5 8.7 0.0 2.3 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain rve PF00665.21 EKG09419.1 - 6.9e-11 42.3 0.1 2.4e-10 40.5 0.1 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EKG09419.1 - 8.7e-05 22.0 0.1 0.00024 20.7 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EKG09419.1 - 0.051 13.1 2.2 0.4 10.2 0.0 3.3 3 0 0 3 3 3 0 Integrase core domain DUF521 PF04412.8 EKG09419.1 - 0.067 11.7 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) p450 PF00067.17 EKG09420.1 - 1.6e-14 53.3 0.0 1.7e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_psq PF05225.11 EKG09421.1 - 2.9e-10 39.5 0.1 3e-10 39.4 0.1 1.0 1 0 0 1 1 1 1 helix-turn-helix, Psq domain NUMOD1 PF07453.8 EKG09421.1 - 0.0068 16.2 0.0 0.0084 15.9 0.0 1.1 1 0 0 1 1 1 1 NUMOD1 domain DUF3562 PF12085.3 EKG09421.1 - 0.072 12.9 0.0 0.072 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) TFIID-18kDa PF02269.11 EKG09422.1 - 3.5e-25 87.6 0.2 6.6e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EKG09422.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone adh_short PF00106.20 EKG09423.1 - 5.4e-17 62.2 1.5 5.4e-17 62.2 1.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG09423.1 - 6.7e-06 25.8 0.5 9.7e-06 25.3 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG09423.1 - 0.00051 19.8 0.0 0.00078 19.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG09423.1 - 0.00099 19.1 0.3 0.0016 18.4 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKG09423.1 - 0.0099 15.6 0.1 0.03 14.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG09423.1 - 0.011 15.1 0.1 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PsbN PF02468.10 EKG09425.1 - 0.026 14.1 0.3 0.053 13.1 0.2 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) RNase_H PF00075.19 EKG09426.1 - 2.7e-05 24.5 0.0 5.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09426.1 - 5.3e-05 22.9 0.1 0.00022 20.9 0.1 2.0 1 1 0 1 1 1 1 Reverse transcriptase-like DUF1176 PF06674.6 EKG09426.1 - 0.06 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Dimer_Tnp_hAT PF05699.9 EKG09428.1 - 1.5e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF863 PF05904.6 EKG09428.1 - 0.046 12.0 0.4 0.048 11.9 0.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) ATP-synt_E PF05680.7 EKG09428.1 - 0.059 13.3 3.0 0.088 12.7 2.1 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF3121 PF11319.3 EKG09428.1 - 0.089 12.2 1.7 0.11 12.0 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) DUF3306 PF11748.3 EKG09428.1 - 1 10.0 6.3 1.4 9.5 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) HLH PF00010.21 EKG09429.1 - 7.1e-09 35.2 0.2 2.9e-08 33.2 0.1 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mito_fiss_reg PF05308.6 EKG09429.1 - 1.9 7.7 11.6 0.05 12.9 0.9 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator bZIP_1 PF00170.16 EKG09430.1 - 7.4e-09 35.4 6.2 7.4e-09 35.4 4.3 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EKG09430.1 - 3.4e-06 26.7 16.5 6e-06 25.9 5.6 2.6 1 1 1 2 2 2 1 Basic region leucine zipper Gypsy PF07253.6 EKG09430.1 - 0.076 11.3 0.1 0.13 10.5 0.1 1.4 1 0 0 1 1 1 0 Gypsy protein SecD-TM1 PF13721.1 EKG09430.1 - 0.095 12.9 0.8 0.2 11.9 0.5 1.5 1 0 0 1 1 1 0 SecD export protein N-terminal TM region Apt1 PF10351.4 EKG09430.1 - 3.9 6.2 9.9 5.1 5.8 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain UcrQ PF02939.11 EKG09434.1 - 4.6e-23 80.8 0.0 5.3e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 UcrQ family p450 PF00067.17 EKG09435.1 - 5.3e-10 38.4 0.0 7.2e-10 37.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 rve PF00665.21 EKG09436.1 - 7.5e-20 71.2 0.0 1.3e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EKG09436.1 - 1.1e-07 31.3 0.1 2.7e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EKG09436.1 - 0.0035 16.8 0.3 0.089 12.3 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain Nop14 PF04147.7 EKG09436.1 - 0.24 9.2 11.8 0.36 8.7 8.2 1.2 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 EKG09436.1 - 1.1 9.2 11.6 2.1 8.3 8.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AvrE PF11725.3 EKG09436.1 - 2.3 5.1 9.0 3.1 4.7 6.3 1.1 1 0 0 1 1 1 0 Pathogenicity factor Hid1 PF12722.2 EKG09436.1 - 4.2 4.9 7.1 5.5 4.5 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EKG09436.1 - 6 4.7 12.8 8.5 4.2 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Epimerase PF01370.16 EKG09437.1 - 4.5e-08 32.8 0.4 1.6e-05 24.4 0.3 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG09437.1 - 0.0035 16.0 0.0 0.73 8.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG09437.1 - 0.027 13.3 0.0 0.08 11.8 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.1 EKG09437.1 - 0.12 12.4 0.0 0.37 10.7 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 EKG09438.1 - 4.3e-16 58.6 0.1 9.7e-15 54.2 0.1 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG09438.1 - 1.9e-07 32.0 0.1 3.2e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 EKG09438.1 - 0.069 13.0 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Ank_2 PF12796.2 EKG09441.1 - 1.3e-20 73.5 0.0 4.7e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG09441.1 - 2.7e-19 69.1 0.0 7.6e-11 42.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EKG09441.1 - 6e-17 60.5 0.0 7.4e-07 28.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EKG09441.1 - 7e-15 53.6 0.0 4.2e-05 23.3 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EKG09441.1 - 2.9e-08 33.6 0.0 0.001 19.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HTH_11 PF08279.7 EKG09441.1 - 0.093 12.3 0.1 0.8 9.4 0.0 2.6 3 0 0 3 3 3 0 HTH domain DUF2075 PF09848.4 EKG09442.1 - 0.0037 16.3 0.3 0.053 12.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EKG09442.1 - 0.0037 17.2 0.9 0.027 14.4 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EKG09442.1 - 0.0052 16.2 0.0 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 EKG09442.1 - 0.0082 15.8 0.1 0.022 14.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EKG09442.1 - 0.0088 16.1 0.0 0.053 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2464 PF10240.4 EKG09442.1 - 0.016 14.5 0.1 0.04 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2464) T2SE PF00437.15 EKG09442.1 - 0.025 13.5 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EKG09442.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 EKG09442.1 - 0.029 13.3 0.2 0.1 11.5 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain AAA_29 PF13555.1 EKG09442.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1031 PF06275.6 EKG09442.1 - 0.068 13.2 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) Spore_coat_CotO PF14153.1 EKG09444.1 - 0.0099 15.3 6.8 0.016 14.6 4.7 1.3 1 0 0 1 1 1 1 Spore coat protein CotO HSDR_N_2 PF13588.1 EKG09444.1 - 0.051 13.3 0.0 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) RP-C_C PF11800.3 EKG09444.1 - 0.21 11.2 11.6 0.47 10.1 8.0 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Ycf1 PF05758.7 EKG09444.1 - 0.25 9.0 5.4 0.33 8.6 3.8 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 EKG09444.1 - 0.55 8.7 4.2 0.86 8.1 2.9 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ARGLU PF15346.1 EKG09444.1 - 0.56 9.9 41.4 1.3 8.8 28.7 1.6 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 APH PF01636.18 EKG09444.1 - 6.4 6.4 15.6 0.037 13.7 0.7 3.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Zn_Tnp_IS91 PF14319.1 EKG09445.1 - 0.43 10.1 6.2 0.7 9.4 4.3 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain RNase_H PF00075.19 EKG09446.1 - 5.1e-06 26.8 0.0 9.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG09446.1 - 6.1e-06 25.9 0.3 2.5e-05 23.9 0.2 2.0 1 1 0 1 1 1 1 Reverse transcriptase-like DUF1176 PF06674.6 EKG09446.1 - 0.058 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) HTH_Tnp_Tc5 PF03221.11 EKG09447.1 - 0.0044 16.7 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG09447.1 - 0.057 12.9 0.1 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 helix-turn-helix, Psq domain UDPGT PF00201.13 EKG09448.1 - 2.1e-10 39.7 0.0 8.7e-10 37.7 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EKG09448.1 - 7.7e-06 25.3 0.0 0.0047 16.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EKG09448.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_4_2 PF13477.1 EKG09448.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like OAF PF14941.1 EKG09449.1 - 0.0062 15.7 0.2 1.8 7.6 0.1 2.4 2 0 0 2 2 2 2 Transcriptional regulator, Out at first Paralemmin PF03285.10 EKG09449.1 - 0.12 11.8 2.2 0.16 11.3 1.6 1.2 1 0 0 1 1 1 0 Paralemmin bZIP_2 PF07716.10 EKG09449.1 - 0.24 11.2 5.1 0.081 12.7 0.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF2497 PF10691.4 EKG09449.1 - 0.56 10.2 5.0 0.64 10.0 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) IncA PF04156.9 EKG09449.1 - 0.77 9.3 4.1 1.5 8.3 2.8 1.5 1 0 0 1 1 1 0 IncA protein DUF4404 PF14357.1 EKG09449.1 - 2.5 8.5 8.8 1.9 8.9 2.5 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) GlutR_dimer PF00745.15 EKG09449.1 - 3.6 7.5 8.6 4.6 7.2 2.1 2.4 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain HTH_psq PF05225.11 EKG09450.1 - 1.9e-09 36.9 1.4 2.7e-09 36.4 0.2 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 EKG09450.1 - 5e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_ISL3 PF13542.1 EKG09450.1 - 0.067 12.3 0.1 0.21 10.7 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_28 PF13518.1 EKG09450.1 - 0.18 11.8 0.8 0.81 9.7 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Dimer_Tnp_hAT PF05699.9 EKG09451.1 - 2.3e-19 68.8 0.1 4.4e-19 67.8 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region HLH PF00010.21 EKG09452.1 - 1.6e-07 30.9 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Dehyd-heme_bind PF09098.5 EKG09453.1 - 0.13 11.6 2.6 0.46 9.9 0.1 2.2 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Dimer_Tnp_hAT PF05699.9 EKG09454.1 - 1.6e-13 50.0 0.1 2.8e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Flg_hook PF02120.11 EKG09454.1 - 0.026 14.1 0.1 0.3 10.7 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK Pyr_redox_2 PF07992.9 EKG09455.1 - 7.8e-37 127.1 0.4 7.2e-20 71.7 0.0 4.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG09455.1 - 1.9e-18 66.6 2.5 1.1e-15 57.7 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.15 EKG09455.1 - 4.6e-17 62.4 0.0 1.4e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox_dim PF02852.17 EKG09455.1 - 1.5e-13 50.7 0.0 1.2e-12 47.8 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain DAO PF01266.19 EKG09455.1 - 3.2e-10 39.4 2.0 0.018 13.9 0.1 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG09455.1 - 1.3e-08 34.7 0.2 0.0089 16.0 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG09455.1 - 5.6e-07 29.8 0.0 1.3e-05 25.3 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG09455.1 - 6.1e-05 21.6 1.1 0.56 8.6 0.0 3.8 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_9 PF13454.1 EKG09455.1 - 0.0032 17.2 4.2 13 5.4 0.0 4.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EKG09455.1 - 0.0046 15.8 1.7 0.8 8.4 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.16 EKG09455.1 - 0.0051 16.3 0.0 0.02 14.4 0.0 2.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EKG09455.1 - 0.0099 16.1 0.1 6.7 7.0 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.1 EKG09455.1 - 0.015 14.2 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EKG09455.1 - 0.019 13.8 1.2 0.14 10.9 0.0 2.5 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EKG09455.1 - 0.042 12.9 1.7 0.5 9.3 0.2 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG09455.1 - 0.057 12.3 2.1 6.1 5.6 0.0 3.4 3 1 1 4 4 4 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EKG09455.1 - 0.12 10.9 0.1 1.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HLH PF00010.21 EKG09461.1 - 0.00054 19.6 0.1 0.0029 17.2 0.1 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 EKG09461.1 - 0.0033 17.0 0.4 0.0079 15.8 0.3 1.6 1 0 0 1 1 1 1 Homeobox associated leucine zipper Rab5-bind PF09311.6 EKG09461.1 - 0.091 12.6 0.9 0.091 12.6 0.6 1.7 2 0 0 2 2 2 0 Rabaptin-like protein bZIP_Maf PF03131.12 EKG09461.1 - 0.11 12.8 2.1 11 6.3 0.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Glycos_transf_1 PF00534.15 EKG09462.1 - 3.4e-25 88.4 0.0 7.4e-25 87.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EKG09462.1 - 2e-11 44.2 0.0 1.6e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EKG09462.1 - 6.3e-05 23.1 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EKG09462.1 - 0.06 11.8 0.0 1.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 20 RTA1 PF04479.8 EKG09463.1 - 1.5e-21 76.9 10.4 1.5e-21 76.9 7.2 1.6 1 1 1 2 2 2 1 RTA1 like protein Dimer_Tnp_hAT PF05699.9 EKG09464.1 - 1.3e-16 59.9 0.3 6.3e-16 57.7 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4451 PF14616.1 EKG09465.1 - 0.048 13.4 0.6 0.06 13.1 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) zf-H2C2_5 PF13909.1 EKG09465.1 - 0.071 13.3 0.9 0.15 12.3 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF4608 PF15381.1 EKG09465.1 - 0.072 13.2 2.1 0.24 11.5 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4608) zf-BED PF02892.10 EKG09465.1 - 0.12 12.1 2.2 0.22 11.3 1.5 1.5 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 EKG09465.1 - 1.6 9.2 6.1 0.27 11.6 1.3 1.9 3 0 0 3 3 3 0 C2H2-type zinc finger RVT_2 PF07727.9 EKG09467.1 - 1.9e-86 289.0 0.0 2.7e-86 288.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EKG09467.1 - 8.9e-13 48.3 0.1 2.4e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EKG09467.1 - 1.5e-05 24.4 0.0 4.7e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC_5 PF14787.1 EKG09467.1 - 0.02 14.3 0.2 0.061 12.8 0.1 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVT_1 PF00078.22 EKG09467.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2360 PF10152.4 EKG09468.1 - 0.064 13.5 0.4 0.064 13.5 0.3 3.2 3 2 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) bZIP_1 PF00170.16 EKG09470.1 - 1.3e-09 37.8 4.7 2.2e-09 37.1 3.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG09470.1 - 6.5e-05 22.6 4.9 0.00019 21.1 3.4 1.7 1 1 0 1 1 1 1 Basic region leucine zipper zf-CCHC PF00098.18 EKG09471.1 - 0.0023 17.7 3.4 0.0023 17.7 2.4 2.2 2 0 0 2 2 2 1 Zinc knuckle RVT_1 PF00078.22 EKG09472.1 - 3e-10 39.8 0.0 5.9e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4574 PF15141.1 EKG09472.1 - 0.13 12.0 0.2 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) Dimer_Tnp_hAT PF05699.9 EKG09473.1 - 5.6e-11 41.9 0.1 9.6e-11 41.1 0.1 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region OMPdecase PF00215.19 EKG09475.1 - 2.4e-66 223.3 0.0 2.9e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family BetaGal_dom3 PF13363.1 EKG09475.1 - 0.15 11.4 0.1 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF4407 PF14362.1 EKG09476.1 - 2.3 7.0 5.8 3.7 6.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HTH_Tnp_Tc5 PF03221.11 EKG09478.1 - 4.1e-11 42.5 0.0 2.2e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EKG09478.1 - 1.1e-06 28.1 0.1 3e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_23 PF13384.1 EKG09478.1 - 0.058 13.0 0.3 0.56 9.9 0.1 2.2 2 0 0 2 2 2 0 Homeodomain-like domain POP1 PF06978.6 EKG09478.1 - 0.083 12.5 1.6 0.078 12.6 1.1 1.3 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 zf-C2H2 PF00096.21 EKG09479.1 - 1e-13 50.7 46.2 0.002 18.3 1.2 7.7 7 1 1 8 8 8 5 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EKG09479.1 - 4.8e-09 36.0 33.1 0.3 11.2 3.5 7.1 6 1 1 7 7 7 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EKG09479.1 - 5.7e-09 35.6 46.4 0.26 11.7 0.7 8.0 8 0 0 8 8 8 5 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG09479.1 - 0.00033 20.8 0.3 0.00033 20.8 0.2 7.0 7 1 0 7 7 7 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EKG09479.1 - 0.026 14.4 0.7 0.026 14.4 0.5 5.9 6 0 0 6 6 6 0 C2H2-type zinc finger zf-met PF12874.2 EKG09479.1 - 0.038 14.2 36.2 0.055 13.6 0.0 6.7 7 1 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EKG09479.1 - 0.95 9.6 28.3 7.6 6.7 0.0 5.0 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) CASP_C PF08172.7 EKG09481.1 - 1.4e-05 24.3 4.4 1.4e-05 24.3 3.0 1.7 2 0 0 2 2 2 1 CASP C terminal TMF_DNA_bd PF12329.3 EKG09481.1 - 0.00066 19.4 8.3 0.0019 17.9 5.8 1.8 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Fmp27_WPPW PF10359.4 EKG09481.1 - 0.0011 17.5 1.7 0.0015 16.9 1.2 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CENP-Q PF13094.1 EKG09481.1 - 0.0012 18.9 8.5 0.0044 17.0 5.7 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF2968 PF11180.3 EKG09481.1 - 0.0015 17.9 7.0 0.0032 16.8 4.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DivIVA PF05103.8 EKG09481.1 - 0.0063 16.5 5.1 0.015 15.3 3.5 1.6 1 0 0 1 1 1 1 DivIVA protein Lebercilin PF15619.1 EKG09481.1 - 0.0099 15.3 6.2 0.019 14.3 4.3 1.5 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease ADIP PF11559.3 EKG09481.1 - 0.013 15.3 8.0 0.025 14.4 5.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3498 PF12004.3 EKG09481.1 - 0.015 14.4 5.2 0.024 13.7 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) ArsR PF09824.4 EKG09481.1 - 0.02 14.1 0.1 0.037 13.3 0.1 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator NTPase_1 PF03266.10 EKG09481.1 - 0.024 14.3 0.3 0.057 13.1 0.2 1.6 1 0 0 1 1 1 0 NTPase Apolipoprotein PF01442.13 EKG09481.1 - 0.027 13.9 9.9 0.02 14.4 5.2 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 EKG09481.1 - 0.044 13.3 3.4 0.096 12.2 2.3 1.5 1 0 0 1 1 1 0 IncA protein Nsp1_C PF05064.8 EKG09481.1 - 0.057 13.0 2.9 0.11 12.1 1.1 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region GBP_C PF02841.9 EKG09481.1 - 0.064 12.4 6.5 0.11 11.6 4.5 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain APG6 PF04111.7 EKG09481.1 - 0.085 11.8 5.0 0.14 11.1 3.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 EKG09481.1 - 0.09 12.7 4.6 0.18 11.7 0.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMCO5 PF14992.1 EKG09481.1 - 0.11 11.6 4.7 0.24 10.5 3.2 1.5 1 0 0 1 1 1 0 TMCO5 family Jnk-SapK_ap_N PF09744.4 EKG09481.1 - 0.16 11.9 5.8 0.37 10.7 4.0 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 ACCA PF03255.9 EKG09481.1 - 0.19 11.3 1.9 0.38 10.3 1.3 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Phage_GP20 PF06810.6 EKG09481.1 - 0.19 11.1 3.2 1 8.7 1.1 2.5 2 1 0 2 2 2 0 Phage minor structural protein GP20 CDC37_N PF03234.9 EKG09481.1 - 0.25 11.6 5.4 0.54 10.5 3.7 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding PhoU PF01895.14 EKG09481.1 - 0.37 11.2 3.7 1.2 9.5 2.6 1.9 1 1 0 1 1 1 0 PhoU domain DUF1515 PF07439.6 EKG09481.1 - 0.43 10.4 3.7 1.2 8.9 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF724 PF05266.9 EKG09481.1 - 0.65 9.5 6.6 0.9 9.1 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF2508 PF10704.4 EKG09481.1 - 0.7 10.0 6.2 12 6.1 1.0 3.1 2 1 1 3 3 2 0 Protein of unknown function (DUF2508) MbeD_MobD PF04899.7 EKG09481.1 - 2 8.3 8.2 3.7 7.5 0.4 3.3 2 1 1 3 3 3 0 MbeD/MobD like SlyX PF04102.7 EKG09481.1 - 2.2 8.7 10.7 58 4.1 0.9 3.8 2 1 1 3 3 3 0 SlyX Mod_r PF07200.8 EKG09481.1 - 2.9 7.8 11.2 0.68 9.8 4.3 2.3 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein MULE PF10551.4 EKG09483.1 - 8.8e-13 48.2 0.2 4.4e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 EKG09483.1 - 0.004 15.7 0.1 0.011 14.2 0.0 1.8 2 0 0 2 2 2 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.10 EKG09483.1 - 0.057 12.9 0.2 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 MuDR family transposase FAR1 PF03101.10 EKG09483.1 - 0.24 11.9 5.8 0.047 14.2 1.0 1.9 2 0 0 2 2 2 0 FAR1 DNA-binding domain PIF1 PF05970.9 EKG09485.1 - 3.2e-08 32.9 0.0 6.7e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.1 EKG09487.1 - 2.2e-12 47.1 0.1 3.2e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Caa3_CtaG PF09678.5 EKG09487.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) Arrestin_N PF00339.24 EKG09489.1 - 9.6e-09 35.2 0.0 8.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKG09489.1 - 1.8e-06 28.0 0.0 0.00011 22.3 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Chitin_synth_2 PF03142.10 EKG09490.1 - 7.8e-10 37.7 0.6 2.1e-08 33.0 0.4 2.0 1 1 0 1 1 1 1 Chitin synthase Glyco_transf_21 PF13506.1 EKG09490.1 - 2.7e-07 30.0 1.0 9.1e-07 28.3 0.7 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EKG09490.1 - 1.1e-06 28.4 4.1 1.5e-06 28.0 2.9 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG09490.1 - 2e-06 27.8 0.1 3.6e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EKG09490.1 - 1.9e-05 24.4 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Myb_DNA-bind_6 PF13921.1 EKG09491.1 - 0.00045 20.2 0.1 0.0011 19.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG09491.1 - 0.0017 18.4 0.2 0.003 17.5 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain PAS_9 PF13426.1 EKG09492.1 - 3.3e-19 69.1 0.0 1.8e-13 50.7 0.0 3.9 4 0 0 4 4 4 2 PAS domain PAS_3 PF08447.6 EKG09492.1 - 7e-13 48.4 1.2 7e-13 48.4 0.8 1.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EKG09492.1 - 3.9e-10 39.5 0.0 6.3e-08 32.4 0.0 3.3 4 0 0 4 4 4 1 PAS fold PAS_4 PF08448.5 EKG09492.1 - 3.4e-09 36.6 0.0 9e-06 25.6 0.0 3.5 4 0 0 4 4 4 2 PAS fold PAS_10 PF13596.1 EKG09492.1 - 0.083 13.1 0.0 12 6.2 0.0 2.9 3 0 0 3 3 3 0 PAS domain HATPase_c PF02518.21 EKG09493.1 - 4.4e-28 97.2 0.1 8.8e-28 96.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG09493.1 - 2e-23 82.5 0.6 3e-22 78.7 0.3 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EKG09493.1 - 8e-21 73.8 0.1 1.7e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EKG09493.1 - 0.00021 20.9 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_1 PF00170.16 EKG09494.1 - 5.6e-12 45.4 9.3 5.6e-12 45.4 6.4 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EKG09494.1 - 6.7e-08 32.2 5.8 6.7e-08 32.2 4.0 2.0 3 0 0 3 3 3 1 Basic region leucine zipper DivIC PF04977.10 EKG09494.1 - 0.0042 16.5 2.6 0.012 15.0 1.8 1.7 1 0 0 1 1 1 1 Septum formation initiator DUF1465 PF07323.7 EKG09494.1 - 0.014 15.0 0.6 0.024 14.1 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) bZIP_Maf PF03131.12 EKG09494.1 - 0.021 15.1 4.9 0.021 15.1 3.4 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor Rsbr_N PF08678.5 EKG09494.1 - 0.044 13.6 0.4 0.078 12.8 0.3 1.3 1 0 0 1 1 1 0 Rsbr N terminal Serine_rich PF08824.5 EKG09494.1 - 0.058 13.1 0.2 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain Apis_Csd PF11671.3 EKG09494.1 - 0.65 9.7 4.0 1.1 9.0 2.8 1.3 1 0 0 1 1 1 0 Complementary sex determiner protein Fungal_trans PF04082.13 EKG09496.1 - 1.4e-27 96.2 0.1 2.1e-27 95.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG09496.1 - 2.1e-07 30.7 11.9 4.3e-07 29.7 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_6 PF14259.1 EKG09497.1 - 6.5e-11 42.0 0.0 8.8e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG09497.1 - 6.2e-06 25.9 0.0 9.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG09497.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3723 PF12520.3 EKG09498.1 - 8e-20 70.8 0.0 1.1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Stimulus_sens_1 PF13756.1 EKG09498.1 - 0.084 13.2 0.1 0.71 10.2 0.0 2.4 1 1 1 2 2 2 0 Stimulus-sensing domain Pkinase PF00069.20 EKG09499.1 - 1e-10 41.2 0.7 1.4e-10 40.7 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09499.1 - 1.1e-05 24.7 0.4 1.4e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG09499.1 - 0.034 13.0 0.0 0.19 10.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.20 EKG09500.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain TMF_DNA_bd PF12329.3 EKG09503.1 - 4.5e-07 29.5 32.7 0.0031 17.3 11.7 3.5 1 1 4 5 5 5 3 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EKG09503.1 - 9.6e-06 25.5 22.6 0.0033 17.3 2.7 2.3 1 1 0 2 2 2 2 Afadin- and alpha -actinin-Binding CCDC144C PF14915.1 EKG09503.1 - 0.00012 21.1 18.7 0.00017 20.6 13.0 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region AAA_13 PF13166.1 EKG09503.1 - 0.00014 20.4 19.2 0.00096 17.7 1.3 2.0 1 1 1 2 2 2 2 AAA domain IncA PF04156.9 EKG09503.1 - 0.00049 19.7 28.1 0.15 11.6 7.1 2.1 1 1 1 2 2 2 2 IncA protein Tropomyosin PF00261.15 EKG09503.1 - 0.0024 16.9 8.5 0.0024 16.9 5.9 2.4 1 1 0 2 2 2 1 Tropomyosin DUF745 PF05335.8 EKG09503.1 - 0.0025 17.3 12.8 0.0031 17.0 8.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF745) Reo_sigmaC PF04582.7 EKG09503.1 - 0.0026 16.9 4.1 0.0097 15.1 3.0 1.6 1 1 0 1 1 1 1 Reovirus sigma C capsid protein Gp58 PF07902.6 EKG09503.1 - 0.0035 15.6 6.9 0.0048 15.1 4.8 1.1 1 0 0 1 1 1 1 gp58-like protein Filament PF00038.16 EKG09503.1 - 0.0064 15.9 22.8 0.15 11.5 7.5 2.1 1 1 1 2 2 2 2 Intermediate filament protein Cast PF10174.4 EKG09503.1 - 0.0072 14.4 18.9 0.011 13.8 13.1 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone TPR_MLP1_2 PF07926.7 EKG09503.1 - 0.0074 16.0 22.6 0.031 14.0 7.3 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 EKG09503.1 - 0.022 14.2 23.0 0.34 10.4 7.2 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliD_C PF07195.7 EKG09503.1 - 0.024 13.9 12.9 0.066 12.4 4.1 2.4 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DASH_Hsk3 PF08227.6 EKG09503.1 - 0.025 14.7 2.5 2.9 8.1 0.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF241 PF03087.9 EKG09503.1 - 0.027 13.9 13.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 0 Arabidopsis protein of unknown function DUF3584 PF12128.3 EKG09503.1 - 0.032 11.5 15.6 0.041 11.2 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 EKG09503.1 - 0.035 13.8 17.5 0.021 14.5 6.7 2.4 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.6 EKG09503.1 - 0.046 13.5 24.2 0.39 10.5 9.0 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EKG09503.1 - 0.057 13.7 21.7 0.28 11.5 7.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Jnk-SapK_ap_N PF09744.4 EKG09503.1 - 0.062 13.3 21.4 1.4 8.9 8.1 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 MtrG PF04210.8 EKG09503.1 - 0.063 12.9 0.4 23 4.7 0.1 3.2 3 0 0 3 3 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Tropomyosin_1 PF12718.2 EKG09503.1 - 0.067 13.0 30.2 0.36 10.6 19.7 2.6 1 1 2 3 3 3 0 Tropomyosin like Lge1 PF11488.3 EKG09503.1 - 0.077 13.2 17.3 0.066 13.4 8.7 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 APG6 PF04111.7 EKG09503.1 - 0.084 11.9 24.7 0.48 9.4 5.1 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 EKG09503.1 - 0.098 12.7 16.2 4.5 7.3 9.6 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EKG09503.1 - 0.11 11.7 26.4 1.1 8.4 10.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Peptidase_C6 PF00851.13 EKG09503.1 - 0.11 11.0 2.9 0.15 10.7 2.0 1.1 1 0 0 1 1 1 0 Helper component proteinase PspA_IM30 PF04012.7 EKG09503.1 - 0.14 11.4 22.8 1.5 8.1 14.4 2.2 1 1 1 2 2 2 0 PspA/IM30 family Lebercilin PF15619.1 EKG09503.1 - 0.15 11.4 25.9 1.2 8.4 11.2 2.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.3 EKG09503.1 - 0.25 11.1 25.6 4 7.2 4.4 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.7 EKG09503.1 - 0.29 11.3 9.2 2.6 8.3 1.0 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF536 PF04394.9 EKG09503.1 - 0.35 10.6 0.2 0.35 10.6 0.1 3.9 5 0 0 5 5 2 0 Protein of unknown function, DUF536 DUF948 PF06103.6 EKG09503.1 - 0.39 10.6 8.9 17 5.3 3.5 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.7 EKG09503.1 - 0.39 10.5 8.9 2.3 8.0 5.7 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.4 EKG09503.1 - 0.4 10.9 12.5 0.55 10.4 3.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.1 EKG09503.1 - 0.48 9.3 9.8 0.79 8.6 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EzrA PF06160.7 EKG09503.1 - 0.48 8.5 20.3 1.8 6.6 4.0 2.0 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA HAUS5 PF14817.1 EKG09503.1 - 0.49 8.8 16.4 0.53 8.7 4.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 HlyD PF00529.15 EKG09503.1 - 0.51 9.5 10.1 0.79 8.9 7.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein MAD PF05557.8 EKG09503.1 - 0.52 8.3 25.9 1.6 6.6 11.8 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Atg14 PF10186.4 EKG09503.1 - 0.61 8.9 21.3 0.77 8.6 13.6 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 EKG09503.1 - 0.66 9.8 29.4 0.25 11.1 10.8 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UVR PF02151.14 EKG09503.1 - 0.75 9.3 7.5 1.2 8.7 1.0 3.4 2 0 0 2 2 2 0 UvrB/uvrC motif Nup54 PF13874.1 EKG09503.1 - 0.78 9.3 16.0 0.78 9.3 1.7 2.5 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF1465 PF07323.7 EKG09503.1 - 0.87 9.1 9.6 0.57 9.7 3.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) bZIP_1 PF00170.16 EKG09503.1 - 0.91 9.5 21.0 0.39 10.7 0.5 4.2 2 2 2 4 4 4 0 bZIP transcription factor DUF3450 PF11932.3 EKG09503.1 - 0.94 8.6 16.8 0.48 9.6 6.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Mnd1 PF03962.10 EKG09503.1 - 0.94 9.1 22.1 2.9 7.5 7.8 2.3 1 1 1 2 2 2 0 Mnd1 family COG2 PF06148.6 EKG09503.1 - 0.98 9.2 15.8 16 5.3 2.8 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EKG09503.1 - 1.1 7.8 23.9 0.55 8.8 11.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-Q PF13094.1 EKG09503.1 - 1.1 9.2 26.9 1.9 8.4 9.1 3.6 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit TMCO5 PF14992.1 EKG09503.1 - 1.2 8.1 19.4 2 7.5 13.4 1.4 1 0 0 1 1 1 0 TMCO5 family DUF1664 PF07889.7 EKG09503.1 - 1.3 8.8 13.2 0.64 9.8 3.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FemAB PF02388.11 EKG09503.1 - 1.3 7.6 13.6 0.33 9.5 2.2 2.1 1 1 1 2 2 2 0 FemAB family Herpes_U30 PF04523.8 EKG09503.1 - 1.3 6.3 5.9 1.6 6.1 0.2 1.8 1 1 1 2 2 2 0 Herpes virus tegument protein U30 Pox_A_type_inc PF04508.7 EKG09503.1 - 1.4 8.8 16.0 10 6.2 0.1 5.5 5 0 0 5 5 4 0 Viral A-type inclusion protein repeat DUF812 PF05667.6 EKG09503.1 - 2 6.8 23.4 11 4.3 0.0 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF812) Cob_adeno_trans PF01923.13 EKG09503.1 - 2 8.1 7.8 1.3 8.7 1.6 2.6 1 1 2 3 3 3 0 Cobalamin adenosyltransferase WXG100 PF06013.7 EKG09503.1 - 2.1 8.3 7.4 76 3.4 3.5 3.6 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DUF4298 PF14131.1 EKG09503.1 - 2.9 7.8 11.1 1.2 9.0 0.5 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4298) DUF641 PF04859.7 EKG09503.1 - 3.2 7.5 19.3 4.7 6.9 0.1 3.5 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) Uds1 PF15456.1 EKG09503.1 - 3.2 7.7 20.3 42 4.1 0.5 3.1 1 1 1 2 2 2 0 Up-regulated During Septation Prominin PF05478.6 EKG09503.1 - 3.3 5.1 11.7 14 3.0 7.8 2.0 1 1 0 1 1 1 0 Prominin CDC37_N PF03234.9 EKG09503.1 - 3.5 7.9 16.8 4.9 7.4 11.0 1.7 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding KLRAQ PF10205.4 EKG09503.1 - 3.7 7.6 17.5 1.1 9.2 6.5 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4140 PF13600.1 EKG09503.1 - 3.8 8.0 17.1 3.6 8.0 2.2 3.4 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) THOC7 PF05615.8 EKG09503.1 - 4 7.7 21.7 0.16 12.2 1.5 3.4 1 1 1 2 2 1 0 Tho complex subunit 7 Osmo_CC PF08946.5 EKG09503.1 - 4.5 7.3 11.2 3.1 7.8 0.1 4.2 3 1 0 4 4 4 0 Osmosensory transporter coiled coil Striatin PF08232.7 EKG09503.1 - 4.9 7.4 22.0 7 6.9 4.3 2.8 1 1 2 3 3 3 0 Striatin family SlyX PF04102.7 EKG09503.1 - 5.2 7.5 17.7 3.8 7.9 5.1 4.0 1 1 2 3 3 3 0 SlyX Sec8_exocyst PF04048.9 EKG09503.1 - 5.6 6.5 14.6 39 3.8 0.3 3.3 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.14 EKG09503.1 - 6.2 4.5 18.5 6.6 4.4 10.7 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ERM PF00769.14 EKG09503.1 - 6.4 6.2 24.0 2.5 7.5 14.9 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GLE1 PF07817.8 EKG09503.1 - 6.6 5.5 9.0 1.5 7.6 2.1 2.3 1 1 1 2 2 2 0 GLE1-like protein Snapin_Pallidin PF14712.1 EKG09503.1 - 6.8 7.0 15.5 6.3 7.1 4.7 3.2 2 1 1 3 3 2 0 Snapin/Pallidin TMPIT PF07851.8 EKG09503.1 - 7.2 5.5 14.6 1.4 7.9 6.9 1.9 1 1 0 2 2 2 0 TMPIT-like protein Orbi_VP5 PF00901.12 EKG09503.1 - 8 4.5 13.3 11 4.0 9.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Phage_GP20 PF06810.6 EKG09503.1 - 8.6 5.7 23.5 6 6.2 2.1 3.4 1 1 3 4 4 4 0 Phage minor structural protein GP20 DUF4200 PF13863.1 EKG09503.1 - 8.6 6.3 27.0 19 5.1 5.5 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DivIC PF04977.10 EKG09503.1 - 8.8 5.8 26.4 0.14 11.6 3.6 4.3 1 1 2 4 4 4 0 Septum formation initiator Dimer_Tnp_hAT PF05699.9 EKG09507.1 - 6e-13 48.2 0.1 9.1e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ribosomal_S20p PF01649.13 EKG09507.1 - 0.12 12.7 0.6 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S20 Uds1 PF15456.1 EKG09508.1 - 0.11 12.4 0.9 0.29 11.1 0.0 2.0 2 1 0 2 2 2 0 Up-regulated During Septation Cu-oxidase_3 PF07732.10 EKG09511.1 - 6.8e-35 119.3 0.4 6.8e-35 119.3 0.3 2.9 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EKG09511.1 - 9.1e-29 100.4 0.9 6.5e-26 91.1 0.1 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG09511.1 - 5.2e-26 90.8 11.6 4.4e-23 81.3 0.4 3.6 3 2 0 3 3 3 2 Multicopper oxidase ketoacyl-synt PF00109.21 EKG09515.1 - 1.1e-69 234.7 0.1 3.9e-69 232.9 0.1 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EKG09515.1 - 1.6e-69 234.3 1.8 1.6e-69 234.3 1.2 1.7 2 0 0 2 2 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EKG09515.1 - 2.1e-58 198.1 0.1 3.5e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EKG09515.1 - 1.8e-57 193.9 3.9 4.1e-57 192.7 2.7 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKG09515.1 - 4.4e-49 166.6 5.2 1.7e-48 164.7 3.6 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG09515.1 - 4.8e-34 116.7 0.0 1.5e-33 115.2 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EKG09515.1 - 4.5e-17 62.3 0.0 1.6e-16 60.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG09515.1 - 2.1e-11 43.7 0.0 1.3e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG09515.1 - 3.5e-10 40.4 0.0 9.5e-07 29.3 0.0 4.1 5 0 0 5 5 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG09515.1 - 1.1e-09 37.9 0.0 2.9e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG09515.1 - 4.1e-08 33.6 0.0 2.6e-07 31.0 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EKG09515.1 - 8.8e-07 27.9 0.0 1.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 EKG09515.1 - 2.5e-06 27.6 0.8 8.7e-06 25.9 0.4 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EKG09515.1 - 5.4e-06 25.5 0.0 8.7e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 EKG09515.1 - 1.8e-05 24.3 0.6 0.0018 17.8 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 EKG09515.1 - 8.5e-05 21.7 0.0 0.00022 20.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EKG09515.1 - 0.00017 20.6 0.7 0.00034 19.6 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EKG09515.1 - 0.0022 17.6 0.3 0.0086 15.7 0.2 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Epimerase PF01370.16 EKG09515.1 - 0.0034 16.8 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EKG09515.1 - 0.023 14.4 1.2 0.048 13.4 0.8 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DNA_gyraseB_C PF00986.16 EKG09515.1 - 0.39 10.4 0.0 1.1 9.0 0.0 1.7 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Methyltransf_28 PF02636.12 EKG09515.1 - 0.4 10.0 0.0 0.77 9.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MFS_1 PF07690.11 EKG09516.1 - 4.5e-28 97.9 78.6 1.1e-27 96.6 43.3 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG09516.1 - 2e-10 39.8 19.9 2e-10 39.8 13.8 3.8 1 1 4 5 5 5 1 Sugar (and other) transporter B12D PF06522.6 EKG09516.1 - 0.12 12.0 0.1 0.74 9.5 0.1 2.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit FAD_binding_3 PF01494.14 EKG09517.1 - 1.9e-23 83.0 0.5 9.5e-23 80.8 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG09517.1 - 1.1e-07 31.1 2.0 5.7e-06 25.4 0.3 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG09517.1 - 1.3e-07 31.5 0.3 3.7e-07 30.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG09517.1 - 0.00021 21.6 0.9 0.0035 17.7 0.6 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG09517.1 - 0.00035 20.5 0.8 0.0011 18.9 0.5 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG09517.1 - 0.00039 19.3 0.1 0.00055 18.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EKG09517.1 - 0.0004 19.1 0.8 0.12 10.9 0.2 3.0 2 1 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EKG09517.1 - 0.00046 19.1 0.2 0.00071 18.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EKG09517.1 - 0.0065 15.4 0.2 0.041 12.8 0.2 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.5 EKG09517.1 - 0.013 14.3 0.0 0.92 8.2 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EKG09517.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 EKG09517.1 - 0.031 14.3 0.1 0.07 13.1 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG09517.1 - 0.039 13.7 0.3 0.6 9.8 0.0 2.4 2 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EKG09517.1 - 0.13 10.6 0.1 0.39 9.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein SpoIIIAH PF12685.2 EKG09518.1 - 0.02 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein MFS_1 PF07690.11 EKG09521.1 - 5.3e-16 58.2 19.4 6.8e-16 57.9 13.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ECH PF00378.15 EKG09522.1 - 1.5e-27 96.3 0.0 1.9e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Lipoxygenase PF00305.14 EKG09523.1 - 2.5e-15 55.5 0.0 2.9e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Lipoxygenase Peroxidase_2 PF01328.12 EKG09524.1 - 1.5e-06 27.1 0.0 1.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 4HBT_2 PF13279.1 EKG09525.1 - 1.8e-06 28.4 0.0 2.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EKG09525.1 - 0.051 13.7 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily p450 PF00067.17 EKG09526.1 - 1.8e-46 158.6 0.0 2.3e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Apolipoprotein PF01442.13 EKG09527.1 - 0.04 13.4 9.2 0.11 11.9 4.4 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain HemX PF04375.9 EKG09527.1 - 0.051 12.1 0.7 0.072 11.6 0.5 1.2 1 0 0 1 1 1 0 HemX AAA_32 PF13654.1 EKG09527.1 - 0.11 11.1 2.4 0.15 10.7 1.6 1.1 1 0 0 1 1 1 0 AAA domain Borrelia_REV PF03978.8 EKG09527.1 - 0.12 12.1 0.3 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF1515 PF07439.6 EKG09527.1 - 0.14 11.9 1.4 0.29 10.9 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Baculo_PEP_C PF04513.7 EKG09527.1 - 0.15 11.8 0.2 0.42 10.4 0.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 EKG09527.1 - 0.25 10.8 1.5 0.39 10.2 0.7 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FUSC PF04632.7 EKG09527.1 - 1.6 7.0 3.7 0.83 8.0 1.2 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF883 PF05957.8 EKG09527.1 - 1.6 9.1 5.0 8.2 6.9 1.5 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) IncA PF04156.9 EKG09527.1 - 5.9 6.4 8.3 9.7 5.7 5.7 1.3 1 0 0 1 1 1 0 IncA protein Pyr_redox_3 PF13738.1 EKG09528.1 - 3.9e-26 92.3 0.3 4.8e-25 88.8 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG09528.1 - 2.6e-14 52.3 0.7 3.2e-13 48.7 0.5 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EKG09528.1 - 1.8e-13 50.1 0.0 4.6e-08 32.3 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EKG09528.1 - 1e-08 35.3 0.0 1.8e-06 27.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG09528.1 - 2.2e-07 30.8 0.2 8.2e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG09528.1 - 2.7e-06 26.5 5.1 0.00054 18.9 0.2 3.3 2 2 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG09528.1 - 1.6e-05 24.7 0.2 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Thi4 PF01946.12 EKG09528.1 - 2e-05 23.7 0.1 0.013 14.6 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 EKG09528.1 - 4.5e-05 23.7 0.1 0.075 13.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG09528.1 - 0.00012 22.1 0.0 0.084 12.9 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EKG09528.1 - 0.00045 19.3 0.1 0.00093 18.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EKG09528.1 - 0.0035 16.3 0.9 0.22 10.3 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EKG09528.1 - 0.006 15.4 0.4 0.019 13.8 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EKG09528.1 - 0.014 14.2 0.1 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EKG09528.1 - 0.015 13.7 0.4 0.037 12.4 0.0 1.8 3 0 0 3 3 3 0 HI0933-like protein F420_oxidored PF03807.12 EKG09528.1 - 0.075 13.4 0.0 10 6.6 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sugar_tr PF00083.19 EKG09529.1 - 1e-23 83.6 1.3 1.4e-23 83.2 0.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG09529.1 - 3.2e-05 22.8 11.7 4.4e-05 22.3 8.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1725 PF08333.6 EKG09529.1 - 0.12 11.6 0.2 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) HSBP1 PF06825.7 EKG09530.1 - 0.0024 17.3 0.3 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 Heat shock factor binding protein 1 DUF1664 PF07889.7 EKG09530.1 - 0.01 15.6 0.2 0.17 11.7 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.4 EKG09530.1 - 0.012 14.9 0.1 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Apolipoprotein PF01442.13 EKG09530.1 - 0.15 11.5 3.2 0.49 9.8 2.2 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Abhydrolase_6 PF12697.2 EKG09532.1 - 1.6e-24 87.0 0.0 1.8e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG09532.1 - 4.1e-16 59.2 0.0 1e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG09532.1 - 1.1e-07 31.6 0.3 2.3e-06 27.4 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EKG09532.1 - 0.025 13.8 0.2 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.4 EKG09532.1 - 0.036 13.3 0.1 0.065 12.4 0.1 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase BAAT_C PF08840.6 EKG09532.1 - 0.048 13.3 0.1 0.49 10.0 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EKG09532.1 - 0.073 12.4 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.15 EKG09532.1 - 0.094 12.9 0.1 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Amidohydro_1 PF01979.15 EKG09534.1 - 0.00071 19.3 0.0 0.00092 18.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EKG09534.1 - 0.033 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family zf-H2C2_2 PF13465.1 EKG09536.1 - 0.023 14.9 0.8 0.084 13.2 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain MCPVI PF02993.9 EKG09536.1 - 0.03 14.4 4.4 0.042 13.9 3.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI zf-C2H2_4 PF13894.1 EKG09536.1 - 0.036 14.4 1.3 2.2 8.7 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger NACHT PF05729.7 EKG09537.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Clathrin-link PF09268.5 EKG09537.1 - 1.8 7.7 4.4 3.7 6.6 0.2 2.6 2 0 0 2 2 2 0 Clathrin, heavy-chain linker SNF2_N PF00176.18 EKG09538.1 - 3e-64 216.6 0.2 4.1e-64 216.2 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EKG09538.1 - 2e-07 30.9 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKG09538.1 - 1.8e-05 24.2 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 EKG09538.1 - 0.00053 19.4 0.4 0.00098 18.5 0.3 1.4 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 EKG09538.1 - 0.0097 16.0 0.1 0.027 14.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain Caps_synth PF05704.7 EKG09540.1 - 7.2e-12 45.0 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EKG09540.1 - 0.0044 17.3 0.0 0.008 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TauD PF02668.11 EKG09541.1 - 7e-22 78.3 1.0 1.2e-21 77.5 0.7 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.17 EKG09542.1 - 6.8e-30 103.9 0.2 7.7e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG09544.1 - 3.4e-61 207.1 0.0 4.2e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EKG09545.1 - 2.7e-15 56.2 0.1 4.8e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EKG09545.1 - 4.5e-05 23.1 0.1 0.00016 21.4 0.1 2.0 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.2 EKG09545.1 - 0.012 15.2 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.5 EKG09545.1 - 0.019 14.5 0.1 0.043 13.4 0.1 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_24 PF13412.1 EKG09545.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 EKG09545.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator HTH_20 PF12840.2 EKG09545.1 - 0.15 11.8 0.5 1.7 8.4 0.0 2.7 2 1 1 3 3 3 0 Helix-turn-helix domain MBOAT_2 PF13813.1 EKG09546.1 - 9.1e-21 73.7 3.1 1.8e-20 72.7 2.2 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family BPD_transp_2 PF02653.11 EKG09546.1 - 2.3 7.1 7.6 0.14 11.0 0.6 2.2 3 0 0 3 3 3 0 Branched-chain amino acid transport system / permease component Methyltransf_23 PF13489.1 EKG09547.1 - 0.00046 19.9 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG09547.1 - 0.032 14.7 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EKG09547.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain p450 PF00067.17 EKG09548.1 - 1.5e-17 63.3 0.0 1.7e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 EKG09549.1 - 8.2e-11 42.0 0.0 8.8e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ketoacyl-synt PF00109.21 EKG09551.1 - 9.6e-73 244.7 0.4 3.8e-72 242.8 0.3 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG09551.1 - 2.2e-59 201.3 1.3 8.3e-53 179.7 0.2 2.7 2 0 0 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG09551.1 - 4.3e-36 123.3 0.5 1.5e-35 121.6 0.3 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EKG09551.1 - 2.7e-23 82.5 11.1 8.9e-23 80.8 7.7 2.0 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EKG09551.1 - 1.1e-22 81.4 0.1 1.3e-21 77.9 0.0 2.6 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EKG09551.1 - 8.9e-19 67.5 1.3 1.3e-08 34.9 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EKG09551.1 - 8.6e-11 42.1 11.3 8.6e-11 42.1 7.9 4.4 2 1 1 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG09551.1 - 3.8e-08 33.2 11.2 7.1e-06 25.8 0.7 3.8 3 1 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EKG09551.1 - 3.7e-06 26.1 0.0 8.7e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 EKG09551.1 - 0.4 10.0 0.0 0.96 8.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Cupin_2 PF07883.6 EKG09552.1 - 1.3e-08 34.1 0.4 2.5e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Cupin domain FAD_binding_3 PF01494.14 EKG09553.1 - 2.7e-14 52.9 0.0 3.2e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG09553.1 - 1.3e-11 43.9 9.1 1.7e-06 27.2 0.7 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG09553.1 - 1.8e-07 31.4 0.3 0.00059 20.1 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG09553.1 - 5.1e-07 29.6 0.2 1.4e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG09553.1 - 9.4e-07 28.0 3.7 9.4e-07 28.0 2.5 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG09553.1 - 1.1e-06 28.6 0.3 6.8e-06 26.1 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG09553.1 - 6.6e-06 24.8 1.6 0.00012 20.6 0.7 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EKG09553.1 - 1e-05 25.7 0.1 1.9e-05 24.8 0.1 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG09553.1 - 5.6e-05 22.4 1.4 6.7e-05 22.1 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EKG09553.1 - 0.00023 20.7 0.6 0.00066 19.2 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EKG09553.1 - 0.001 18.0 1.3 0.0023 16.8 0.9 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.17 EKG09553.1 - 0.0017 17.2 0.3 0.0063 15.4 0.5 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EKG09553.1 - 0.0038 15.9 0.4 0.0065 15.1 0.3 1.3 1 0 0 1 1 1 1 Tryptophan halogenase 3HCDH_N PF02737.13 EKG09553.1 - 0.095 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EKG09553.1 - 0.15 11.1 0.4 0.46 9.5 0.1 1.7 2 0 0 2 2 2 0 Thi4 family GST_N_3 PF13417.1 EKG09554.1 - 1.4e-14 54.0 0.0 2.6e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG09554.1 - 5.3e-13 48.9 0.0 9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG09554.1 - 3.4e-12 46.1 0.0 7.2e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EKG09554.1 - 2.2e-09 37.1 0.1 4.4e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG09554.1 - 6.2e-06 26.0 0.2 1.2e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG09554.1 - 0.0013 19.1 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EKG09554.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.6 2 0 0 2 2 2 0 MetRS-N binding domain Cu-oxidase_2 PF07731.9 EKG09556.1 - 9.4e-30 102.9 0.4 1.1e-29 102.6 0.3 1.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EKG09557.1 - 9.1e-23 80.9 0.0 1.2e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG09558.1 - 0.001 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase FMN_red PF03358.10 EKG09559.1 - 1.5e-32 112.2 0.4 2e-32 111.7 0.3 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EKG09559.1 - 6.1e-11 42.1 0.9 2e-10 40.5 0.3 1.9 1 1 0 2 2 2 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EKG09559.1 - 0.037 14.0 0.1 6.8 6.6 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain MFS_1 PF07690.11 EKG09560.1 - 2.7e-05 23.0 18.5 0.0016 17.2 0.3 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily BT1 PF03092.11 EKG09560.1 - 0.26 9.9 3.5 0.27 9.8 1.4 1.6 2 0 0 2 2 2 0 BT1 family DUF4118 PF13493.1 EKG09560.1 - 1.1 9.5 0.1 1.1 9.5 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4118) FA_desaturase PF00487.19 EKG09560.1 - 3 7.1 12.0 0.24 10.8 2.0 2.0 1 1 1 2 2 2 0 Fatty acid desaturase Fungal_trans PF04082.13 EKG09561.1 - 2.7e-17 62.5 0.0 4e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Kelch_5 PF13854.1 EKG09562.1 - 2e-10 40.3 1.4 2e-10 40.3 1.0 3.6 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.1 EKG09562.1 - 1.8e-05 24.3 7.5 0.0013 18.4 0.1 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EKG09562.1 - 0.00022 21.2 3.7 0.28 11.4 0.1 3.7 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EKG09562.1 - 0.015 15.4 13.1 0.028 14.5 0.1 4.2 4 1 0 4 4 4 0 Galactose oxidase, central domain Kelch_1 PF01344.20 EKG09562.1 - 0.016 14.7 1.0 12 5.5 0.0 3.6 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.20 EKG09564.1 - 9.2e-23 80.7 0.0 1.2e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09564.1 - 7.2e-16 58.0 0.0 9.3e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF478 PF04334.7 EKG09565.1 - 0.037 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF478) DUF3435 PF11917.3 EKG09566.1 - 7.2e-125 416.9 1.0 8.8e-125 416.6 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) RIIa PF02197.12 EKG09566.1 - 0.073 12.5 0.2 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Ank_5 PF13857.1 EKG09569.1 - 1.2e-13 50.8 0.3 0.0053 16.9 0.0 5.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG09569.1 - 1.7e-12 47.4 0.8 0.021 15.3 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG09569.1 - 2.3e-11 43.8 0.1 2.2e-05 24.6 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) NACHT PF05729.7 EKG09569.1 - 2.5e-11 43.5 0.0 6.8e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EKG09569.1 - 2.8e-09 37.2 0.0 1e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG09569.1 - 3.2e-09 36.9 0.0 1.2e-08 35.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Ank_3 PF13606.1 EKG09569.1 - 1.7e-05 24.6 0.2 6.4 7.3 0.0 6.3 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.25 EKG09569.1 - 8.3e-05 22.2 0.4 3.5 7.5 0.0 5.0 4 0 0 4 4 4 1 Ankyrin repeat KAP_NTPase PF07693.9 EKG09569.1 - 0.00016 20.7 0.0 0.00047 19.2 0.0 1.6 1 1 0 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 EKG09569.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EKG09569.1 - 0.007 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TIR_2 PF13676.1 EKG09569.1 - 0.038 14.1 0.2 16 5.7 0.0 3.0 2 0 0 2 2 2 0 TIR domain AAA_10 PF12846.2 EKG09569.1 - 0.055 12.9 0.0 0.41 10.0 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA PF00004.24 EKG09569.1 - 0.13 12.4 0.0 0.54 10.4 0.0 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EKG09569.1 - 0.24 11.5 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase DUF1664 PF07889.7 EKG09571.1 - 0.44 10.3 10.4 4.1 7.2 0.1 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) GED PF02212.13 EKG09571.1 - 1.5 8.7 4.8 0.91 9.4 0.3 2.8 3 0 0 3 3 3 0 Dynamin GTPase effector domain Effector_1 PF04518.7 EKG09571.1 - 2.1 7.2 7.8 0.25 10.3 0.3 2.7 3 1 1 4 4 4 0 Effector from type III secretion system NPV_P10 PF05531.7 EKG09571.1 - 2.7 8.2 8.2 0.52 10.6 0.3 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EKG09571.1 - 3.2 6.8 10.5 0.85 8.7 0.1 2.5 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Kdo PF06293.9 EKG09572.1 - 4.2e-06 25.9 0.7 6.3e-06 25.4 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG09572.1 - 0.0003 20.6 1.7 0.00073 19.3 1.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EKG09572.1 - 0.0011 18.1 0.5 0.0016 17.6 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EKG09572.1 - 0.0045 16.3 0.1 0.0071 15.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EKG09572.1 - 0.076 12.5 0.0 1.4 8.4 0.0 2.2 1 1 0 1 1 1 0 Choline/ethanolamine kinase WaaY PF06176.6 EKG09572.1 - 0.12 11.5 0.1 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF1889 PF08986.5 EKG09578.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1889) DUF2360 PF10152.4 EKG09579.1 - 0.0064 16.7 0.7 0.013 15.8 0.5 1.4 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) NPV_P10 PF05531.7 EKG09579.1 - 0.12 12.6 1.1 5.8 7.2 0.2 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein EST1_DNA_bind PF10373.4 EKG09582.1 - 7e-10 38.5 0.8 1.4e-09 37.5 0.5 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain F420_ligase PF01996.11 EKG09582.1 - 0.21 10.6 0.1 0.36 9.8 0.1 1.3 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase JmjC PF02373.17 EKG09583.1 - 1.4e-19 70.3 0.0 3e-11 43.5 0.0 2.7 2 0 0 2 2 2 2 JmjC domain, hydroxylase DUF605 PF04652.11 EKG09583.1 - 0.00097 18.6 9.4 0.0023 17.4 6.5 1.6 1 0 0 1 1 1 1 Vta1 like CDC45 PF02724.9 EKG09583.1 - 0.32 8.9 3.2 0.53 8.2 2.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EKG09583.1 - 7.9 4.2 9.9 12 3.6 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EKG09583.1 - 9.8 4.7 15.4 19 3.7 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Gate PF07670.9 EKG09586.1 - 0.023 14.5 0.1 0.035 14.0 0.0 1.5 1 1 0 1 1 1 0 Nucleoside recognition FTO_CTD PF12934.2 EKG09587.1 - 0.083 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 FTO C-terminal domain OEP PF02321.13 EKG09587.1 - 0.13 11.8 1.7 0.21 11.1 1.2 1.3 1 1 0 1 1 1 0 Outer membrane efflux protein DUF1996 PF09362.5 EKG09588.1 - 1.1e-38 133.2 0.1 1.3e-38 132.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RWD PF05773.17 EKG09588.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain FAD_binding_8 PF08022.7 EKG09589.1 - 4e-13 49.1 0.0 7.7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain U5_2-snRNA_bdg PF10597.4 EKG09590.1 - 0.082 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Mto2_bdg PF12808.2 EKG09590.1 - 0.12 12.5 0.6 0.46 10.6 0.1 2.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TSC22 PF01166.13 EKG09590.1 - 0.2 11.6 0.9 0.57 10.1 0.1 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF848 PF05852.6 EKG09591.1 - 0.0018 18.1 0.8 0.0026 17.6 0.6 1.3 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Cortex-I_coil PF09304.5 EKG09591.1 - 0.01 15.8 1.0 0.015 15.3 0.7 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Spectrin PF00435.16 EKG09591.1 - 0.014 15.6 1.7 0.025 14.8 1.2 1.4 1 1 0 1 1 1 0 Spectrin repeat Syntaxin PF00804.20 EKG09591.1 - 0.014 15.5 0.6 0.027 14.6 0.4 1.5 1 0 0 1 1 1 0 Syntaxin Syntaxin-6_N PF09177.6 EKG09591.1 - 0.018 15.4 0.2 0.032 14.6 0.1 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Cob_adeno_trans PF01923.13 EKG09591.1 - 0.023 14.4 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase GrpE PF01025.14 EKG09591.1 - 0.028 13.9 0.3 0.037 13.5 0.2 1.2 1 0 0 1 1 1 0 GrpE Mnd1 PF03962.10 EKG09591.1 - 0.062 12.9 0.1 0.068 12.8 0.1 1.1 1 0 0 1 1 1 0 Mnd1 family COG2 PF06148.6 EKG09591.1 - 0.07 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cytochrom_B562 PF07361.6 EKG09591.1 - 0.099 13.0 1.1 0.14 12.5 0.3 1.7 2 0 0 2 2 2 0 Cytochrome b562 ApoO PF09769.4 EKG09591.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein O Baculo_PEP_C PF04513.7 EKG09591.1 - 0.11 12.2 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MbeB_N PF04837.7 EKG09591.1 - 0.13 12.3 1.0 0.34 11.0 0.7 1.7 1 0 0 1 1 1 0 MbeB-like, N-term conserved region XhlA PF10779.4 EKG09591.1 - 0.17 11.8 3.7 0.38 10.6 2.6 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Myb_DNA-bind_6 PF13921.1 EKG09592.1 - 0.0021 18.1 0.1 0.0044 17.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG09592.1 - 0.0045 16.9 0.1 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKG09592.1 - 0.032 14.1 1.8 0.082 12.8 1.1 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain WEMBL PF05701.6 EKG09593.1 - 0.00025 19.6 23.1 0.0013 17.2 5.8 2.0 1 1 1 2 2 2 2 Weak chloroplast movement under blue light DUF4294 PF14127.1 EKG09593.1 - 0.013 15.1 3.0 0.013 15.1 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) DivIC PF04977.10 EKG09593.1 - 0.027 13.9 14.1 0.12 11.8 4.2 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF4259 PF14078.1 EKG09593.1 - 0.065 13.7 6.1 0.13 12.8 4.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Fzo_mitofusin PF04799.8 EKG09593.1 - 0.12 11.6 9.3 0.032 13.6 3.5 1.9 2 0 0 2 2 2 0 fzo-like conserved region TSC22 PF01166.13 EKG09593.1 - 0.21 11.5 8.5 0.061 13.2 2.8 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Sec8_exocyst PF04048.9 EKG09593.1 - 0.29 10.7 6.6 2.1 7.9 0.6 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain WXG100 PF06013.7 EKG09593.1 - 0.66 10.0 6.4 3.5 7.6 0.5 2.8 2 2 0 2 2 2 0 Proteins of 100 residues with WXG Fez1 PF06818.10 EKG09593.1 - 1.2 9.0 21.0 10 6.0 14.5 2.0 1 1 0 1 1 1 0 Fez1 Mnd1 PF03962.10 EKG09593.1 - 1.9 8.0 20.9 0.31 10.6 2.0 2.0 1 1 1 2 2 2 0 Mnd1 family MCRS_N PF13325.1 EKG09593.1 - 2.8 7.3 10.0 1.6 8.2 5.6 1.5 1 1 0 1 1 1 0 N-terminal region of micro-spherule protein DUF607 PF04678.8 EKG09593.1 - 6.5 6.6 14.1 1.9 8.3 4.3 2.1 1 1 0 2 2 2 0 Protein of unknown function, DUF607 Laminin_II PF06009.7 EKG09593.1 - 9.3 6.0 12.5 9.9 5.9 2.7 2.3 1 1 0 2 2 2 0 Laminin Domain II AMP-binding PF00501.23 EKG09594.1 - 9.9e-167 554.5 0.8 2.5e-88 296.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EKG09594.1 - 1.6e-117 391.6 0.0 1.8e-45 155.1 0.0 4.3 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EKG09594.1 - 2.9e-39 133.1 0.0 2.5e-11 43.6 0.0 4.8 4 0 0 4 4 4 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG09594.1 - 3.3e-10 40.7 0.3 0.002 19.0 0.0 3.4 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EKG09594.1 - 0.00018 20.2 0.1 0.0028 16.2 0.0 2.6 3 0 0 3 3 3 1 GH3 auxin-responsive promoter MFS_1 PF07690.11 EKG09595.1 - 2.4e-42 144.8 46.3 2.4e-42 144.8 32.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG09595.1 - 7.7e-14 50.8 24.4 9.8e-14 50.4 16.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Thioesterase PF00975.15 EKG09596.1 - 0.005 17.0 0.0 0.0056 16.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain FAD_binding_3 PF01494.14 EKG09598.1 - 2.1e-18 66.5 0.1 3.2e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG09598.1 - 0.00018 21.4 0.0 0.0014 18.5 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EKG09598.1 - 0.035 12.9 0.0 0.11 11.2 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.22 EKG09598.1 - 0.05 14.0 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4404 PF14357.1 EKG09598.1 - 0.078 13.3 2.2 5.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3435 PF11917.3 EKG09599.1 - 1.1e-29 103.4 0.0 1.4e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF3435 PF11917.3 EKG09600.1 - 1.4e-38 132.7 4.9 1.7e-38 132.4 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Spin-Ssty PF02513.12 EKG09603.1 - 0.1 12.1 0.1 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Spin/Ssty Family Ank_2 PF12796.2 EKG09607.1 - 7.1e-17 61.5 0.1 4.2e-16 59.0 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG09607.1 - 1.2e-16 60.7 0.1 4.9e-07 30.0 0.0 3.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG09607.1 - 2e-14 52.2 0.3 0.00058 19.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeat Ank PF00023.25 EKG09607.1 - 3e-14 51.9 1.1 0.00013 21.5 0.1 3.5 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EKG09607.1 - 1.7e-08 34.4 1.4 0.0033 17.6 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF1843 PF08898.5 EKG09607.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) Zn_clus PF00172.13 EKG09611.1 - 6e-09 35.6 1.6 1.1e-08 34.8 1.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KR PF08659.5 EKG09612.1 - 5.9e-64 215.0 0.2 5.9e-64 215.0 0.2 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EKG09612.1 - 2.9e-48 163.9 0.5 2.9e-48 163.9 0.3 3.2 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EKG09612.1 - 1.8e-10 40.4 1.3 5.6e-10 38.8 0.0 2.5 4 0 0 4 4 4 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EKG09612.1 - 0.00025 20.5 0.0 0.00056 19.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EKG09612.1 - 0.00056 20.1 0.1 0.0022 18.2 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EKG09612.1 - 0.0025 17.5 0.0 0.0062 16.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thioesterase PF00975.15 EKG09613.1 - 1.1e-21 78.1 0.0 2.2e-21 77.1 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EKG09613.1 - 2.6e-08 34.0 0.1 4.1e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG09613.1 - 7.7e-05 22.4 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PP-binding PF00550.20 EKG09613.1 - 0.00017 21.7 0.4 0.00036 20.7 0.3 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2974 PF11187.3 EKG09613.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3649 PF12365.3 EKG09615.1 - 0.11 12.0 0.3 0.11 12.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Peptidase_C48 PF02902.14 EKG09617.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain MCPsignal PF00015.16 EKG09617.1 - 0.027 14.0 6.9 0.45 10.0 2.9 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Dak1_2 PF13684.1 EKG09617.1 - 0.041 12.8 1.7 0.062 12.2 1.2 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family DUF4618 PF15397.1 EKG09617.1 - 1.7 7.8 7.9 8.3 5.6 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) HpaP PF09483.5 EKG09618.1 - 0.052 13.4 2.6 0.15 12.0 1.8 1.7 1 0 0 1 1 1 0 Type III secretion protein (HpaP) TPR_20 PF14561.1 EKG09619.1 - 0.031 14.3 3.9 0.11 12.6 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_L29 PF00831.18 EKG09621.1 - 0.061 13.0 0.3 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Ribosomal L29 protein ABC_tran PF00005.22 EKG09623.1 - 6.6e-23 81.5 0.0 2.2e-22 79.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EKG09623.1 - 8e-09 35.8 0.6 0.00045 20.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EKG09623.1 - 1.2e-05 24.6 0.7 0.017 14.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKG09623.1 - 0.0045 16.4 0.7 0.014 14.9 0.5 1.8 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EKG09623.1 - 0.019 14.3 0.5 0.76 9.1 0.3 2.2 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 EKG09623.1 - 0.029 13.1 0.1 0.049 12.4 0.1 1.3 1 0 0 1 1 1 0 ArgK protein MMR_HSR1 PF01926.18 EKG09623.1 - 0.034 14.1 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EKG09623.1 - 0.056 13.7 0.2 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EKG09623.1 - 0.082 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EKG09623.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EKG09623.1 - 0.19 9.0 0.2 0.27 8.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) E3_UbLigase_R4 PF13764.1 EKG09623.1 - 0.26 9.1 0.9 0.41 8.4 0.6 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 ABC_tran_2 PF12848.2 EKG09623.1 - 2.9 7.7 4.8 3.6 7.5 0.9 2.2 2 0 0 2 2 2 0 ABC transporter ABC_tran PF00005.22 EKG09624.1 - 3.3e-44 150.5 0.0 1.1e-29 103.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKG09624.1 - 2.1e-41 142.1 23.2 9.4e-26 90.8 1.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EKG09624.1 - 7.3e-08 32.7 4.7 0.078 12.9 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 EKG09624.1 - 2.3e-07 30.3 0.1 0.0038 16.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKG09624.1 - 2e-06 27.9 3.7 0.00097 19.1 0.6 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EKG09624.1 - 5.4e-05 22.7 0.5 0.027 13.8 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 EKG09624.1 - 0.00013 21.8 1.1 0.00013 21.8 0.7 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 DUF258 PF03193.11 EKG09624.1 - 0.00014 21.1 0.3 0.1 11.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EKG09624.1 - 0.0002 20.8 1.9 0.46 10.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EKG09624.1 - 0.00033 20.1 0.5 0.021 14.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EKG09624.1 - 0.00049 20.0 2.7 0.014 15.3 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EKG09624.1 - 0.00056 20.3 2.6 0.18 12.1 0.2 2.3 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EKG09624.1 - 0.00085 19.8 1.7 0.08 13.4 0.2 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EKG09624.1 - 0.0019 19.0 0.0 0.37 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EKG09624.1 - 0.0026 16.5 2.0 0.0047 15.7 0.2 2.0 2 0 0 2 2 2 1 ArgK protein SMC_N PF02463.14 EKG09624.1 - 0.0038 16.4 6.4 1.3 8.1 0.2 4.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain MobB PF03205.9 EKG09624.1 - 0.0068 16.1 0.3 0.16 11.6 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EKG09624.1 - 0.0092 16.1 2.4 5.6 7.1 0.3 3.5 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EKG09624.1 - 0.0093 15.6 0.7 0.24 11.0 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase T2SE PF00437.15 EKG09624.1 - 0.011 14.5 0.8 3.4 6.5 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EKG09624.1 - 0.014 14.4 1.7 1.5 7.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 EKG09624.1 - 0.017 14.7 0.2 2.5 7.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 EKG09624.1 - 0.04 12.8 1.8 0.095 11.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EKG09624.1 - 0.044 14.0 0.0 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EKG09624.1 - 0.055 12.0 1.0 0.48 8.9 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EKG09624.1 - 0.062 12.7 3.8 2.2 7.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EKG09624.1 - 0.22 11.2 2.6 0.96 9.2 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain GTP_EFTU PF00009.22 EKG09624.1 - 1 8.7 2.2 19 4.6 0.0 3.0 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EKG09624.1 - 4.4 7.1 8.7 3.8 7.2 0.3 2.7 3 0 0 3 3 2 0 Dynamin family DUF2020 PF09449.5 EKG09626.1 - 0.16 11.6 0.5 0.26 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) Macoilin PF09726.4 EKG09627.1 - 0.00018 19.9 1.8 0.00022 19.6 1.2 1.0 1 0 0 1 1 1 1 Transmembrane protein Macoilin PF09726.4 EKG09628.1 - 0.0018 16.6 2.0 0.0022 16.3 1.4 1.0 1 0 0 1 1 1 1 Transmembrane protein Retrotrans_gag PF03732.12 EKG09629.1 - 3.3e-06 27.0 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein DAO PF01266.19 EKG09630.1 - 0.095 11.5 2.3 0.084 11.7 1.6 1.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Methyltransf_2 PF00891.13 EKG09631.1 - 1.2e-38 132.7 0.0 1.6e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EKG09631.1 - 1.6e-07 31.1 0.0 2.8e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG09631.1 - 1.1e-06 29.2 0.0 2.9e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG09631.1 - 9.9e-06 25.9 0.0 3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG09631.1 - 0.00086 18.9 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG09631.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EKG09631.1 - 0.0018 17.5 0.0 0.004 16.4 0.0 1.5 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 EKG09631.1 - 0.013 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EKG09631.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase GidB PF02527.10 EKG09631.1 - 0.031 13.4 0.2 0.067 12.3 0.0 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DUF3533 PF12051.3 EKG09632.1 - 2.1e-48 164.9 5.8 2.6e-48 164.7 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF4188 PF13826.1 EKG09633.1 - 2.8e-31 108.0 0.2 3.8e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EKG09633.1 - 0.006 15.6 0.0 0.0078 15.2 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Dabb PF07876.7 EKG09633.1 - 0.021 15.2 0.1 0.035 14.5 0.1 1.4 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF1330 PF07045.6 EKG09633.1 - 0.12 12.2 0.1 0.25 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) AMP-binding PF00501.23 EKG09634.1 - 1.1e-58 198.6 0.0 1.3e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EKG09635.1 - 1.8e-06 27.6 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Epimerase PF01370.16 EKG09637.1 - 3.6e-11 42.9 0.0 5.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG09637.1 - 1e-10 40.8 0.3 3e-10 39.2 0.2 1.8 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG09637.1 - 3.4e-07 29.4 0.9 1.5e-05 24.0 0.6 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EKG09637.1 - 0.00027 20.8 0.4 0.0014 18.5 0.2 2.2 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EKG09637.1 - 0.00035 19.8 0.4 0.00099 18.4 0.2 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG09637.1 - 0.00043 20.3 0.3 0.006 16.6 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_6 PF12697.2 EKG09638.1 - 1.1e-24 87.5 0.0 1.5e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG09638.1 - 1.1e-09 38.1 0.0 1.5e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG09638.1 - 3.4e-09 36.6 0.0 8.8e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EKG09638.1 - 0.024 13.1 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family PGAP1 PF07819.8 EKG09638.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.13 EKG09641.1 - 1e-26 93.3 1.0 1.6e-26 92.7 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EKG09641.1 - 3.6e-05 23.8 0.9 3.6e-05 23.8 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG09641.1 - 0.00058 20.0 3.2 0.00058 20.0 2.2 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG09641.1 - 0.0074 16.5 2.8 0.0074 16.5 1.9 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 EKG09641.1 - 0.14 12.2 1.7 0.33 11.0 1.2 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EKG09641.1 - 7.2 7.0 8.0 16 5.9 0.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain GST_C PF00043.20 EKG09642.1 - 5.1e-09 36.0 0.0 8.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG09642.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG09642.1 - 1.1e-06 28.7 0.0 3.4e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG09642.1 - 6.4e-06 25.9 0.9 1.1e-05 25.2 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG09642.1 - 0.00068 20.0 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG09642.1 - 0.0042 17.0 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Big_3 PF07523.7 EKG09642.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) 2OG-FeII_Oxy PF03171.15 EKG09643.1 - 1.3e-12 47.8 0.0 2.5e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EKG09643.1 - 4.2e-12 46.6 0.0 1.2e-11 45.1 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal MFS_1 PF07690.11 EKG09644.1 - 0.00017 20.3 6.6 0.00025 19.8 4.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.6 EKG09644.1 - 0.0077 15.4 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF4131 PF13567.1 EKG09644.1 - 0.096 12.0 0.1 0.096 12.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cu-oxidase_3 PF07732.10 EKG09647.1 - 1.3e-41 140.9 2.5 2.4e-40 136.9 1.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG09647.1 - 1.1e-37 128.6 1.3 1.8e-36 124.7 0.0 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EKG09647.1 - 5.2e-37 127.2 0.2 2.3e-36 125.0 0.0 2.3 2 1 1 3 3 3 1 Multicopper oxidase E1_DerP2_DerF2 PF02221.10 EKG09647.1 - 0.021 15.0 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 ML domain NmrA PF05368.8 EKG09648.1 - 2e-14 53.4 0.0 3.7e-14 52.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG09648.1 - 1.3e-13 51.3 0.2 2.3e-13 50.5 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EKG09648.1 - 1.8e-05 24.2 0.0 0.0001 21.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG09648.1 - 0.018 13.7 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EKG09648.1 - 0.12 11.3 0.3 0.2 10.6 0.1 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase Pyr_redox_3 PF13738.1 EKG09650.1 - 1.5e-26 93.7 0.0 7.2e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG09650.1 - 2.8e-08 33.6 0.0 1.1e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG09650.1 - 4.8e-07 29.8 0.0 0.064 13.1 0.0 3.5 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG09650.1 - 9.8e-07 28.6 0.1 0.00051 19.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EKG09650.1 - 4.3e-06 25.8 0.0 0.00048 19.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EKG09650.1 - 0.00021 19.6 0.0 0.0014 16.8 0.0 2.1 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.15 EKG09650.1 - 0.0019 18.3 0.0 0.072 13.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EKG09650.1 - 0.0046 17.3 0.0 0.68 10.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG09650.1 - 0.017 14.0 0.1 0.078 11.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EKG09650.1 - 0.024 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG09650.1 - 0.14 12.6 0.0 5.5 7.4 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent EHN PF06441.7 EKG09651.1 - 3.3e-30 104.3 0.0 1.1e-29 102.5 0.1 1.8 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG09651.1 - 6.4e-10 39.3 1.2 1.2e-09 38.4 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG09651.1 - 0.041 13.6 0.0 0.37 10.5 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 EKG09652.1 - 8.5e-18 64.8 0.7 4.7e-17 62.4 0.5 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG09652.1 - 8.4e-08 32.0 0.0 2.1e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EKG09652.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Macoilin PF09726.4 EKG09654.1 - 0.00044 18.6 0.8 0.0005 18.5 0.6 1.0 1 0 0 1 1 1 1 Transmembrane protein DLH PF01738.13 EKG09655.1 - 4.9e-20 71.7 0.0 5.4e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG09655.1 - 9.1e-09 35.2 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG09655.1 - 0.00033 20.6 0.1 0.12 12.1 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG09655.1 - 0.021 14.0 0.0 0.61 9.2 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family DUF1100 PF06500.6 EKG09655.1 - 0.038 12.5 0.0 0.055 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) PQQ_3 PF13570.1 EKG09656.1 - 0.18 12.1 9.0 0.17 12.1 1.0 3.4 2 2 1 3 3 3 0 PQQ-like domain DUF3248 PF11609.3 EKG09656.1 - 0.24 11.1 1.0 10 5.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3248) NmrA PF05368.8 EKG09660.1 - 1.7e-17 63.4 0.0 2.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG09660.1 - 5.8e-10 39.4 0.1 9.1e-10 38.8 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG09660.1 - 9.7e-07 28.4 0.1 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG09660.1 - 0.0013 17.5 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EKG09660.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Clr5 PF14420.1 EKG09661.1 - 0.062 13.2 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 Clr5 domain DUF3471 PF11954.3 EKG09663.1 - 0.055 13.3 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) DUF1236 PF06823.7 EKG09663.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) Beta-lactamase PF00144.19 EKG09665.1 - 2e-39 135.5 0.0 2.6e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Pyr_redox_2 PF07992.9 EKG09666.1 - 8.4e-14 51.9 0.0 1.6e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG09666.1 - 7.1e-08 32.7 2.4 1.5e-07 31.7 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG09666.1 - 6e-05 23.1 0.0 0.01 15.8 0.0 3.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG09666.1 - 0.0043 16.0 0.0 0.019 13.8 0.0 2.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EKG09666.1 - 0.015 15.0 0.1 2.1 8.0 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EKG09666.1 - 0.23 10.0 0.9 0.67 8.5 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase ketoacyl-synt PF00109.21 EKG09667.1 - 7.4e-63 212.3 0.0 1.2e-62 211.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EKG09667.1 - 2.1e-45 155.1 1.8 4.1e-45 154.1 1.3 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EKG09667.1 - 3.3e-42 144.9 0.2 1e-41 143.3 0.2 1.8 1 1 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG09667.1 - 4.6e-34 116.8 0.1 1.5e-33 115.1 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EKG09667.1 - 0.00098 18.1 0.1 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 EKG09668.1 - 0.0011 19.3 0.4 0.0036 17.7 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 EKG09670.1 - 1e-21 76.8 0.2 8e-21 73.9 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KR PF08659.5 EKG09670.1 - 1.1e-20 74.0 1.0 3.6e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EKG09670.1 - 4.2e-16 59.3 2.1 1.3e-14 54.5 0.2 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EKG09670.1 - 2.4e-05 25.2 0.0 0.00024 21.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase F420_oxidored PF03807.12 EKG09670.1 - 0.019 15.3 0.4 16 5.9 0.0 2.9 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EKG09670.1 - 0.097 12.6 0.8 5.5 6.9 0.0 2.5 2 1 1 3 3 3 0 NADH(P)-binding Peripla_BP_4 PF13407.1 EKG09670.1 - 0.11 11.8 0.1 0.37 10.1 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein domain TraF PF13728.1 EKG09673.1 - 0.019 14.4 0.4 0.034 13.6 0.2 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein FAD_binding_3 PF01494.14 EKG09674.1 - 1.7e-10 40.5 0.0 2.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF202 PF02656.10 EKG09674.1 - 0.12 12.5 0.2 0.29 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) FAD_binding_3 PF01494.14 EKG09675.1 - 3.6e-15 55.8 0.0 4.6e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EKG09675.1 - 1.3e-05 24.4 0.1 0.0093 15.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EKG09675.1 - 0.00062 18.9 0.0 0.00073 18.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EKG09675.1 - 0.0013 17.7 0.2 0.26 10.1 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG09675.1 - 0.0019 18.2 0.0 0.0063 16.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG09675.1 - 0.0053 17.1 1.3 0.047 14.0 0.1 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase COPI_C PF06957.6 EKG09676.1 - 0.63 8.5 3.3 0.68 8.4 2.3 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SnoaL_3 PF13474.1 EKG09678.1 - 7.5e-08 32.4 0.1 1.2e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EKG09678.1 - 5.3e-07 29.8 0.3 1.5e-06 28.3 0.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) DUF3225 PF11533.3 EKG09678.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) Pyr_redox_3 PF13738.1 EKG09679.1 - 2.6e-23 83.1 0.0 4.2e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG09679.1 - 1.4e-09 37.3 0.0 3.9e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EKG09679.1 - 4.6e-08 31.7 0.0 2e-06 26.3 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EKG09679.1 - 2.1e-06 27.5 0.0 0.15 11.8 0.0 3.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EKG09679.1 - 2.6e-06 27.3 0.0 3.6e-05 23.7 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG09679.1 - 3.2e-06 27.1 1.8 0.38 10.5 0.0 3.6 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG09679.1 - 5e-05 23.4 0.0 0.00047 20.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EKG09679.1 - 0.00054 19.1 0.0 0.0017 17.5 0.0 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG09679.1 - 0.016 15.6 0.0 12 6.4 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EKG09679.1 - 0.038 13.8 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 EKG09679.1 - 0.05 13.4 0.1 12 5.7 0.0 2.5 2 0 0 2 2 2 0 ThiF family ApbA PF02558.11 EKG09679.1 - 0.09 12.2 0.0 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EKG09679.1 - 0.098 12.6 0.0 0.32 10.9 0.0 1.9 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox PF00070.22 EKG09679.1 - 0.15 12.4 6.8 0.15 12.4 0.0 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EKG09679.1 - 0.21 11.6 0.0 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_10 PF13460.1 EKG09680.1 - 1.2e-15 57.9 0.1 1.8e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG09680.1 - 5.2e-10 38.9 0.0 8.8e-10 38.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EKG09680.1 - 3e-06 27.2 0.3 6.3e-06 26.2 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EKG09680.1 - 6.6e-05 22.4 0.1 0.0011 18.4 0.0 2.5 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKG09680.1 - 0.0007 19.3 0.6 0.0037 16.9 0.1 2.0 1 1 1 2 2 2 1 KR domain AlaDh_PNT_C PF01262.16 EKG09680.1 - 0.0031 17.0 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EKG09680.1 - 0.028 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Peripla_BP_4 PF13407.1 EKG09680.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain RasGAP PF00616.14 EKG09683.1 - 3.4e-55 186.7 0.8 1.2e-54 184.9 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EKG09683.1 - 7.1e-31 106.7 4.9 7.1e-31 106.7 3.4 2.6 3 0 0 3 3 3 1 RasGAP C-terminus DUF972 PF06156.8 EKG09683.1 - 1.2 9.5 14.9 1.9 8.9 1.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF4593 PF15263.1 EKG09684.1 - 7.2 6.4 12.8 13 5.6 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) Pyr_redox_2 PF07992.9 EKG09685.1 - 5.1e-31 108.1 0.0 1.5e-30 106.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG09685.1 - 5.6e-12 45.9 0.0 5e-09 36.4 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG09685.1 - 5.9e-05 23.2 0.0 0.68 9.9 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trehalase_Ca-bi PF07492.6 EKG09685.1 - 0.044 13.0 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain DUF4266 PF14086.1 EKG09685.1 - 0.071 13.6 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Shikimate_DH PF01488.15 EKG09685.1 - 0.18 11.9 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3579 PF12112.3 EKG09687.1 - 0.12 12.3 0.0 1.8 8.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3579) Ank_2 PF12796.2 EKG09688.1 - 1.7e-20 73.1 0.1 4.5e-13 49.3 0.0 2.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG09688.1 - 1.2e-15 57.5 0.1 2.5e-08 34.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EKG09688.1 - 5.3e-15 54.3 1.9 4.2e-05 23.1 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EKG09688.1 - 3.5e-14 51.4 0.7 0.00023 21.1 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EKG09688.1 - 1.7e-13 50.3 0.6 1.9e-08 34.2 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG09689.1 - 3.1e-93 306.2 11.7 9.1e-14 51.5 0.0 13.4 7 5 6 14 14 14 12 Ankyrin repeats (3 copies) Ank PF00023.25 EKG09689.1 - 9.3e-67 217.7 33.5 1.2e-05 24.8 0.2 22.6 23 1 0 23 23 23 14 Ankyrin repeat Ank_4 PF13637.1 EKG09689.1 - 6.7e-58 192.1 15.9 7.2e-09 35.9 0.1 17.0 15 3 2 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG09689.1 - 6.4e-57 183.8 22.7 0.0022 18.0 0.0 22.6 24 0 0 24 24 24 10 Ankyrin repeat Ank_5 PF13857.1 EKG09689.1 - 2.3e-51 170.6 26.5 2.3e-05 24.4 0.2 17.0 11 4 8 19 19 19 14 Ankyrin repeats (many copies) NACHT PF05729.7 EKG09689.1 - 1.5e-08 34.4 0.6 6.5e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EKG09689.1 - 1.3e-06 28.5 0.3 1.1e-05 25.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG09689.1 - 7.8e-06 26.0 0.0 3e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKG09689.1 - 0.0067 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EKG09689.1 - 0.014 14.3 0.0 0.26 10.0 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain AAA PF00004.24 EKG09689.1 - 0.12 12.6 0.0 0.38 10.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKG6 PF08693.5 EKG09690.1 - 0.00096 18.4 1.4 0.00096 18.4 1.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Metal_resist PF13801.1 EKG09690.1 - 0.0077 16.2 2.6 0.023 14.6 1.8 1.9 1 0 0 1 1 1 1 Heavy-metal resistance TMEM154 PF15102.1 EKG09690.1 - 0.14 11.9 2.7 8.5 6.0 1.8 2.5 1 1 0 1 1 1 0 TMEM154 protein family CARDB PF07705.6 EKG09690.1 - 0.78 9.8 3.4 1.5 8.9 2.3 1.4 1 0 0 1 1 1 0 CARDB PNPOx_C PF10590.4 EKG09691.1 - 1.2e-21 75.9 4.2 1.7e-21 75.4 1.8 2.2 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EKG09691.1 - 2.5e-18 65.8 0.0 3.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EKG09691.1 - 0.01 16.1 0.1 0.019 15.2 0.1 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Radical_SAM PF04055.16 EKG09693.1 - 4.5e-12 46.4 0.0 7.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EKG09693.1 - 8.8e-06 25.8 0.1 1.6e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EKG09693.1 - 0.00077 19.4 0.3 0.002 18.1 0.2 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Tox-WTIP PF15654.1 EKG09693.1 - 0.096 12.3 2.9 0.25 11.0 2.0 1.6 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Pec_lyase_C PF00544.14 EKG09694.1 - 8.5e-16 58.0 2.3 1.2e-15 57.5 1.6 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EKG09694.1 - 9.3e-07 28.7 9.5 5.4e-06 26.2 6.4 2.0 1 1 0 1 1 1 1 Right handed beta helix region Peptidase_C2 PF00648.16 EKG09695.1 - 2.4e-56 190.9 0.8 1e-41 142.9 0.1 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease p450 PF00067.17 EKG09696.1 - 2.4e-67 227.4 0.0 2.9e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TAP35_44 PF07265.6 EKG09697.1 - 1.1 9.0 6.9 0.07 12.8 0.5 1.9 1 1 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 Abhydrolase_5 PF12695.2 EKG09698.1 - 9.7e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG09698.1 - 0.0015 18.4 1.6 0.0032 17.3 1.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG09698.1 - 0.0077 15.7 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 EKG09698.1 - 0.021 14.1 1.1 0.026 13.7 0.2 1.6 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EKG09698.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_hydro_43 PF04616.9 EKG09699.1 - 1e-32 113.3 6.3 1e-32 113.3 4.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Tannase PF07519.6 EKG09700.1 - 3.6e-38 131.4 0.1 4.1e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase S-methyl_trans PF02574.11 EKG09701.1 - 1.4e-25 90.2 0.0 1e-22 80.8 0.0 2.1 2 0 0 2 2 2 2 Homocysteine S-methyltransferase Rib PF08428.5 EKG09701.1 - 0.11 12.2 0.0 0.62 9.8 0.0 2.2 1 1 1 2 2 2 0 Rib/alpha-like repeat AA_permease PF00324.16 EKG09702.1 - 3e-113 378.6 41.8 3.4e-113 378.5 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG09702.1 - 4.2e-37 127.6 47.3 5.1e-37 127.4 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease SNARE PF05739.14 EKG09703.1 - 0.0094 15.6 3.7 0.027 14.1 0.4 2.5 2 1 0 2 2 2 1 SNARE domain ATG16 PF08614.6 EKG09703.1 - 0.026 14.3 10.9 0.048 13.4 1.3 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AKNA PF12443.3 EKG09703.1 - 0.028 14.4 3.4 1.3 9.1 0.1 2.7 2 1 0 2 2 2 0 AT-hook-containing transcription factor PMEI PF04043.10 EKG09703.1 - 0.18 11.7 1.3 0.35 10.7 0.9 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF16 PF01519.11 EKG09703.1 - 0.18 12.0 1.5 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.7 EKG09703.1 - 0.19 12.0 6.2 3.6 8.0 0.7 2.6 2 1 0 2 2 2 0 SlyX PspA_IM30 PF04012.7 EKG09703.1 - 0.31 10.3 11.6 0.68 9.2 6.6 2.1 1 1 1 2 2 2 0 PspA/IM30 family Adeno_PIX PF03955.9 EKG09703.1 - 0.45 11.0 3.8 1 9.8 0.6 2.2 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF1664 PF07889.7 EKG09703.1 - 0.55 10.0 6.0 3.2 7.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EKG09703.1 - 0.79 10.0 7.5 7 7.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EKG09703.1 - 0.88 9.6 8.2 2 8.5 1.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 EKG09703.1 - 0.89 9.2 4.7 4.4 7.0 0.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Phage_lysis PF03245.8 EKG09703.1 - 0.97 9.4 8.7 9.4 6.2 2.5 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DUF641 PF04859.7 EKG09703.1 - 0.99 9.1 8.8 0.36 10.5 1.0 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 EKG09703.1 - 1.6 8.3 10.8 3.4 7.2 1.8 2.1 2 0 0 2 2 2 0 IncA protein Seryl_tRNA_N PF02403.17 EKG09703.1 - 2.6 8.0 8.1 0.91 9.5 1.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OEP PF02321.13 EKG09703.1 - 2.9 7.4 8.6 6 6.4 1.5 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein FliJ PF02050.11 EKG09703.1 - 4.1 7.4 11.5 3.8 7.5 2.9 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein V_ATPase_I PF01496.14 EKG09703.1 - 8.6 4.0 6.8 1.5 6.5 0.6 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Epimerase PF01370.16 EKG09704.1 - 2.9e-10 39.9 0.1 5.4e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG09704.1 - 1.2e-09 38.3 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG09704.1 - 7.6e-06 24.8 0.1 0.00089 18.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EKG09704.1 - 2.2e-05 24.4 0.1 6.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain NmrA PF05368.8 EKG09704.1 - 0.00021 20.6 0.0 0.00047 19.4 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family ApbA PF02558.11 EKG09704.1 - 0.0093 15.4 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EKG09704.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EKG09706.1 - 2e-08 34.3 0.0 2.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.20 EKG09707.1 - 9e-16 58.2 0.5 3.5e-15 56.3 0.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG09707.1 - 0.00025 20.9 0.0 0.00032 20.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG09707.1 - 0.00061 19.3 0.0 0.00074 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKG09707.1 - 0.0042 16.7 0.4 0.012 15.2 0.3 1.9 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EKG09707.1 - 0.023 14.5 0.2 0.06 13.1 0.2 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain p450 PF00067.17 EKG09708.1 - 4e-69 233.3 0.0 5e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EKG09709.1 - 2.8e-45 154.9 0.0 4.6e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG09709.1 - 1.8e-05 24.7 0.0 7.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EKG09709.1 - 0.00012 20.7 0.0 0.00023 19.7 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EKG09709.1 - 0.00025 20.0 0.0 0.0013 17.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG09709.1 - 0.00052 20.1 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG09709.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EKG09709.1 - 0.0031 16.4 0.0 0.011 14.5 0.0 1.8 1 1 1 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EKG09709.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG09709.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG09709.1 - 0.034 13.0 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EKG09709.1 - 0.047 12.5 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EKG09709.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 EKG09710.1 - 1.7e-71 241.1 0.0 2.2e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PLDc_N PF13396.1 EKG09710.1 - 0.054 13.1 0.6 0.16 11.6 0.4 1.8 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF2334 PF10096.4 EKG09710.1 - 0.061 12.7 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) NAD_binding_10 PF13460.1 EKG09711.1 - 1.1e-12 48.3 0.0 1.6e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG09711.1 - 1.7e-06 27.6 0.0 2.2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG09711.1 - 0.00016 20.4 0.0 0.00021 20.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 EKG09711.1 - 0.00039 19.8 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.8 EKG09711.1 - 0.00062 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EKG09711.1 - 0.0037 16.3 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EKG09711.1 - 0.0042 17.0 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EKG09711.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EKG09711.1 - 0.03 14.2 0.0 0.07 13.0 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase Lactamase_B PF00753.22 EKG09712.1 - 0.027 14.1 2.5 0.094 12.3 1.7 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily NAD_binding_2 PF03446.10 EKG09713.1 - 2.1e-26 92.6 0.0 3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EKG09713.1 - 2.1e-24 85.8 0.0 3.3e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Abhydrolase_6 PF12697.2 EKG09714.1 - 1e-30 107.2 0.4 1.4e-30 106.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG09714.1 - 4.7e-18 65.5 0.0 3.3e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG09714.1 - 1.4e-12 47.5 0.0 5.9e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EKG09714.1 - 4.1e-05 23.4 0.0 0.0001 22.0 0.0 1.6 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.3 EKG09714.1 - 0.003 17.3 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Fungal_trans PF04082.13 EKG09715.1 - 8.2e-17 60.9 1.7 1.2e-16 60.3 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EKG09715.1 - 0.00039 20.5 6.1 0.00039 20.5 4.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EKG09715.1 - 0.0034 17.6 20.4 0.028 14.7 1.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG09715.1 - 0.013 15.8 1.5 0.013 15.8 1.0 3.3 4 0 0 4 4 4 0 C2H2-type zinc finger adh_short PF00106.20 EKG09716.1 - 1.1e-18 67.7 0.1 3e-18 66.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG09716.1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG09716.1 - 7e-07 28.9 0.0 9.9e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EKG09716.1 - 5.3e-06 26.3 0.0 7.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EKG09716.1 - 0.0035 16.2 0.0 0.0056 15.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.9 EKG09718.1 - 6.4e-08 32.7 0.0 6.5e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG09718.1 - 0.00069 19.4 0.0 0.034 13.9 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EKG09718.1 - 0.007 15.3 0.0 0.025 13.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG09718.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG09718.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG09718.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lactamase_B PF00753.22 EKG09719.1 - 2.1e-22 79.7 4.6 3e-22 79.2 3.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG09719.1 - 0.00048 19.7 0.5 0.0012 18.4 0.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG09720.1 - 8.2e-05 22.3 0.9 0.00014 21.5 0.6 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG09720.1 - 0.0043 16.6 0.1 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CinA PF02464.12 EKG09721.1 - 0.066 12.6 0.1 6.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Competence-damaged protein DUF1907 PF08925.6 EKG09721.1 - 0.077 12.0 1.1 6.1 5.8 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1907) Ank_2 PF12796.2 EKG09722.1 - 4.2e-54 180.8 0.4 1.6e-13 50.8 0.0 5.1 3 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EKG09722.1 - 6.2e-48 158.2 21.8 7.9e-08 31.7 0.2 9.7 10 0 0 10 10 10 8 Ankyrin repeat Ank_3 PF13606.1 EKG09722.1 - 3e-39 129.1 10.8 2.4e-05 24.1 0.1 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EKG09722.1 - 8.6e-39 130.6 14.1 1.9e-05 24.7 0.3 8.6 4 3 5 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG09722.1 - 6.1e-35 118.9 9.4 3.2e-09 37.0 0.1 7.5 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Na_Ca_ex PF01699.19 EKG09723.1 - 4.2e-27 94.4 18.7 1.8e-15 56.7 3.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2818 PF10993.3 EKG09723.1 - 0.071 13.6 0.7 0.58 10.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) zf-DHHC PF01529.15 EKG09723.1 - 0.1 11.9 0.1 0.1 11.9 0.1 3.0 3 1 0 3 3 3 0 DHHC palmitoyltransferase DUF4010 PF13194.1 EKG09723.1 - 0.72 9.1 7.9 0.086 12.1 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) PAP2 PF01569.16 EKG09723.1 - 6.5 6.4 8.0 5.5 6.6 0.0 2.9 3 0 0 3 3 3 0 PAP2 superfamily PTR2 PF00854.16 EKG09725.1 - 2.2e-05 23.4 2.0 2.6e-05 23.1 1.4 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 EKG09725.1 - 0.0014 17.4 4.4 0.0017 17.1 3.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_PK PF05891.7 EKG09726.1 - 3.2e-52 176.9 0.1 3.6e-52 176.8 0.1 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EKG09726.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CitG PF01874.11 EKG09726.1 - 0.071 12.3 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase GFO_IDH_MocA_C PF02894.12 EKG09726.1 - 0.083 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Pyr_redox_2 PF07992.9 EKG09726.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Docking PF08990.6 EKG09726.1 - 0.15 11.3 0.3 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Erythronolide synthase docking Adeno_E3_15_3 PF03307.9 EKG09727.1 - 0.028 14.1 0.9 0.057 13.1 0.6 1.5 1 1 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region MFS_3 PF05977.8 EKG09731.1 - 0.068 11.2 0.1 0.095 10.8 0.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector SGL PF08450.7 EKG09732.1 - 2.3e-71 240.0 0.0 2.7e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Peptidase_S9_N PF02897.10 EKG09732.1 - 0.14 10.6 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF1746 PF08508.5 EKG09735.1 - 1.7e-38 131.0 0.0 2.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) HIG_1_N PF04588.8 EKG09736.1 - 1.8e-05 24.3 3.1 3.4e-05 23.4 2.2 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4642 PF15484.1 EKG09736.1 - 0.35 10.8 4.4 0.45 10.4 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF4407 PF14362.1 EKG09736.1 - 1.2 8.0 6.9 1.4 7.8 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Selenoprotein_S PF06936.6 EKG09736.1 - 1.6 8.2 9.8 2.4 7.6 6.8 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF106 PF01956.11 EKG09736.1 - 2.6 7.5 5.0 3.2 7.2 3.5 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 OmpH PF03938.9 EKG09736.1 - 2.8 7.8 9.9 3.1 7.6 6.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDRGK PF09756.4 EKG09736.1 - 6.4 6.1 14.8 7.4 5.9 10.2 1.1 1 0 0 1 1 1 0 DDRGK domain DUF3617 PF12276.3 EKG09737.1 - 0.1 12.0 0.3 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Dus PF01207.12 EKG09738.1 - 0.039 12.7 0.0 0.046 12.5 0.0 1.0 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EKG09739.1 - 1.5e-19 70.1 0.0 1.9e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.19 EKG09740.1 - 6.8e-15 54.8 0.0 1.1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG09740.1 - 8.5e-07 29.0 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG09740.1 - 1e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EKG09740.1 - 2.2e-06 27.8 0.0 5.2e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG09740.1 - 0.0044 16.8 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG09740.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 EKG09741.1 - 3e-06 26.7 0.1 6.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Hydrolase_3 PF08282.7 EKG09744.1 - 2.7e-11 43.5 0.0 7e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase PMM PF03332.8 EKG09744.1 - 2.9e-10 40.0 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 EKG09744.1 - 0.0013 18.1 0.0 0.17 11.1 0.0 2.2 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EKG09744.1 - 0.009 16.4 0.0 0.013 15.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EKG09744.1 - 0.053 12.9 0.0 0.54 9.6 0.0 2.1 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase HAD_2 PF13419.1 EKG09744.1 - 0.056 13.6 0.0 4 7.6 0.0 2.6 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ISN1 PF06437.6 EKG09744.1 - 0.091 11.4 0.0 0.62 8.7 0.0 1.9 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase HAD PF12710.2 EKG09744.1 - 0.14 12.3 0.1 0.34 11.0 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase MS_channel PF00924.13 EKG09744.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel Acid_PPase PF12689.2 EKG09744.1 - 0.15 11.7 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Acid Phosphatase RTA1 PF04479.8 EKG09745.1 - 4.3e-39 134.3 11.2 5.7e-39 133.9 7.7 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF3454 PF11936.3 EKG09746.1 - 0.034 14.3 0.2 0.034 14.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) GFO_IDH_MocA PF01408.17 EKG09748.1 - 9.4e-21 74.5 0.3 1.5e-20 73.9 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EKG09748.1 - 0.0015 18.8 0.1 0.0027 18.0 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG09748.1 - 0.0047 17.3 0.0 0.016 15.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA_C PF02894.12 EKG09748.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain PALP PF00291.20 EKG09749.1 - 2.8e-30 105.6 0.1 3.4e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VSP PF03302.8 EKG09750.1 - 0.00019 20.2 0.2 0.00029 19.6 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein SKG6 PF08693.5 EKG09750.1 - 0.0014 17.8 2.4 0.0025 17.1 1.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EKG09750.1 - 0.0039 16.8 0.2 0.0088 15.7 0.1 1.5 1 1 0 1 1 1 1 Rifin/stevor family PgaD PF13994.1 EKG09750.1 - 0.01 15.3 0.1 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 PgaD-like protein DUF2029 PF09594.5 EKG09750.1 - 0.011 15.2 0.2 0.015 14.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF2500 PF10694.4 EKG09750.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Herpes_gE PF02480.11 EKG09750.1 - 0.012 13.8 0.4 0.022 13.0 0.2 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EKG09750.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.4 EKG09750.1 - 0.027 14.2 1.3 0.059 13.1 0.9 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Shisa PF13908.1 EKG09750.1 - 0.028 14.6 0.0 0.08 13.1 0.0 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM51 PF15345.1 EKG09750.1 - 0.037 13.7 4.1 0.18 11.4 2.9 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 CcmD PF04995.9 EKG09750.1 - 0.039 13.6 1.1 0.12 12.1 0.8 1.8 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) OAD_gamma PF04277.8 EKG09750.1 - 0.052 13.9 1.3 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MtrF PF09472.5 EKG09750.1 - 0.053 12.7 1.7 0.089 12.0 1.2 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syndecan PF01034.15 EKG09750.1 - 0.056 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain DUF4307 PF14155.1 EKG09750.1 - 0.056 13.2 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF4381 PF14316.1 EKG09750.1 - 0.06 13.4 0.4 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Rax2 PF12768.2 EKG09750.1 - 0.065 12.4 0.2 0.15 11.2 0.1 1.5 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Vpu PF00558.14 EKG09750.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Vpu protein DUF3357 PF11837.3 EKG09750.1 - 0.077 12.8 0.4 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) CD99L2 PF12301.3 EKG09750.1 - 0.11 12.1 2.2 0.12 12.0 0.2 2.0 1 1 1 2 2 2 0 CD99 antigen like protein 2 Adeno_E3_CR2 PF02439.10 EKG09750.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2681 PF10883.3 EKG09750.1 - 0.45 10.7 2.7 0.46 10.7 0.7 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) Beta-lactamase PF00144.19 EKG09752.1 - 3.3e-29 101.9 1.8 4.8e-29 101.4 1.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EKG09752.1 - 0.19 10.9 0.0 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Tetraspannin PF00335.15 EKG09753.1 - 4.6 6.4 6.6 1.2e+02 1.8 4.6 2.4 1 1 0 1 1 1 0 Tetraspanin family Abhydrolase_6 PF12697.2 EKG09754.1 - 7.6e-28 97.9 2.2 2.8e-27 96.1 1.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG09754.1 - 4.4e-11 42.7 0.1 3.8e-10 39.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG09754.1 - 7.7e-09 35.4 0.0 4.3e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG09754.1 - 0.021 14.2 0.0 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase GFA PF04828.9 EKG09756.1 - 1.2e-17 63.6 0.1 1.8e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Prim_Zn_Ribbon PF08273.7 EKG09756.1 - 0.034 14.2 2.1 0.067 13.2 0.0 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Nudix_N_2 PF14803.1 EKG09756.1 - 0.063 12.9 0.1 0.063 12.9 0.0 2.7 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.6 EKG09756.1 - 0.09 12.2 4.0 2 8.0 0.1 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 EKG09756.1 - 0.13 11.7 3.3 0.34 10.4 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain PP-binding PF00550.20 EKG09757.1 - 3.7e-10 39.9 0.0 6.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 EKG09757.1 - 2.2e-05 23.0 0.1 3.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme EF-hand_like PF09279.6 EKG09757.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like DUF1748 PF08520.5 EKG09760.1 - 1.3e-33 114.3 0.1 1.5e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 EKG09761.1 - 9.3e-170 563.8 2.8 1.1e-169 563.5 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EKG09761.1 - 7.2e-31 106.1 0.0 3e-29 100.9 0.0 2.5 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EKG09761.1 - 0.00017 20.5 0.4 0.00046 19.1 0.1 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family AMP-binding PF00501.23 EKG09762.1 - 3.6e-66 223.2 0.0 5.2e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG09762.1 - 1.1e-08 35.8 2.7 2.3e-08 34.8 1.9 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TMP-TENI PF02581.12 EKG09762.1 - 0.027 13.5 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DRTGG PF07085.7 EKG09762.1 - 0.099 12.2 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 DRTGG domain MFS_1 PF07690.11 EKG09763.1 - 6.3e-40 136.9 26.5 6.3e-40 136.9 18.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG09763.1 - 1.6e-07 29.9 4.8 2.5e-07 29.2 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG09763.1 - 0.0025 16.4 29.7 0.012 14.1 20.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2668 PF10873.3 EKG09763.1 - 0.98 9.5 0.0 0.98 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) AhpC-TSA PF00578.16 EKG09764.1 - 9.8e-33 112.4 0.0 1.5e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKG09764.1 - 4.1e-13 49.1 0.0 5.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EKG09764.1 - 7.8e-13 47.8 0.2 1.4e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.1 EKG09765.1 - 4.6e-20 71.2 6.5 4.5e-12 45.7 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EKG09765.1 - 5.2e-19 67.7 2.0 6.4e-07 29.0 0.0 5.2 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EKG09765.1 - 2.9e-12 45.9 0.1 0.00013 21.3 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EKG09765.1 - 6.3e-11 41.9 7.1 0.00049 19.9 0.0 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EKG09765.1 - 1.3e-07 31.0 0.1 0.00042 19.9 0.0 4.1 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 EKG09765.1 - 4.9e-07 29.6 3.8 0.12 12.6 0.0 5.1 3 1 1 4 4 4 2 Kelch motif RAG2 PF03089.9 EKG09765.1 - 0.0083 14.8 0.0 0.02 13.6 0.0 1.6 1 1 0 1 1 1 1 Recombination activating protein 2 PAP2 PF01569.16 EKG09768.1 - 2.5e-11 43.3 6.5 2.5e-11 43.3 4.5 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EKG09768.1 - 9.1e-09 35.1 4.1 9.1e-09 35.1 2.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily zf-H2C2_2 PF13465.1 EKG09769.1 - 6.2e-11 42.0 9.0 9.8e-06 25.6 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EKG09769.1 - 1.1e-09 38.0 18.0 2.7e-05 24.2 2.8 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG09769.1 - 2.8e-06 27.2 16.4 0.031 14.6 0.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger HTH_32 PF13565.1 EKG09769.1 - 0.22 12.3 3.6 0.73 10.6 0.4 2.8 3 0 0 3 3 3 0 Homeodomain-like domain Bunya_G2 PF03563.8 EKG09769.1 - 0.79 8.5 2.8 1.2 7.9 1.9 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-LYAR PF08790.6 EKG09769.1 - 1.1 9.0 2.9 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger SprT-like PF10263.4 EKG09769.1 - 1.4 8.5 6.9 21 4.7 4.8 2.3 1 1 0 1 1 1 0 SprT-like family ubiquitin PF00240.18 EKG09770.1 - 9.2e-35 117.8 0.9 1.6e-34 117.0 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKG09770.1 - 3.3e-20 71.5 0.7 6.1e-20 70.6 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_S27 PF01599.14 EKG09770.1 - 5.8e-10 38.8 0.2 1.3e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein S27a Ubiquitin_2 PF14560.1 EKG09770.1 - 5.3e-06 26.5 0.4 2.4e-05 24.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EKG09770.1 - 7.1e-05 22.5 0.2 0.00011 21.9 0.0 1.3 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EKG09770.1 - 0.00041 20.2 0.8 0.0009 19.1 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EKG09770.1 - 0.0025 17.9 0.5 0.0033 17.5 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EKG09770.1 - 0.033 14.2 0.6 0.062 13.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EKG09770.1 - 0.04 12.2 2.4 1.4 7.1 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Mis14 PF08641.7 EKG09771.1 - 7.8e-13 48.6 2.7 1.3e-12 48.0 1.9 1.3 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Filament PF00038.16 EKG09771.1 - 0.002 17.6 1.3 0.0024 17.3 0.9 1.4 1 0 0 1 1 1 1 Intermediate filament protein ATP_bind_2 PF03668.10 EKG09771.1 - 0.13 11.2 0.2 0.16 10.9 0.2 1.2 1 0 0 1 1 1 0 P-loop ATPase protein family HAUS6_N PF14661.1 EKG09771.1 - 0.15 11.4 2.6 0.2 10.9 1.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 EKG09771.1 - 0.23 10.4 3.4 0.28 10.1 2.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Phasin PF05597.6 EKG09771.1 - 0.5 10.1 6.1 0.34 10.6 0.9 2.4 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1682 PF07946.9 EKG09771.1 - 1.4 7.7 5.5 1.7 7.4 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PA14_2 PF10528.4 EKG09772.1 - 2.7e-17 62.7 1.2 2.7e-17 62.7 0.8 2.3 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.7 EKG09772.1 - 7.2e-09 35.4 0.1 1.4e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 PA14 domain Ribonuclease_T2 PF00445.13 EKG09773.1 - 3.2e-32 111.7 0.1 5.6e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Cmc1 PF08583.5 EKG09774.1 - 0.0012 18.5 0.4 0.0012 18.5 0.3 2.1 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Peptidase_M3 PF01432.15 EKG09775.1 - 2.9e-19 69.4 0.2 4.2e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 PAP2 PF01569.16 EKG09777.1 - 8.9e-26 90.0 0.2 2.5e-25 88.6 0.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily MENTAL PF10457.4 EKG09777.1 - 0.14 11.7 2.0 0.23 11.0 1.4 1.3 1 0 0 1 1 1 0 Cholesterol-capturing domain MFS_1 PF07690.11 EKG09779.1 - 5e-20 71.5 27.5 5e-20 71.5 19.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S4e PF00900.15 EKG09779.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal family S4e IncA PF04156.9 EKG09779.1 - 0.77 9.3 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 IncA protein Med8 PF10232.4 EKG09780.1 - 1.6e-19 70.3 0.0 2.3e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 BUD22 PF09073.5 EKG09780.1 - 0.011 14.8 0.5 0.014 14.4 0.4 1.1 1 0 0 1 1 1 0 BUD22 Nucleoplasmin PF03066.10 EKG09780.1 - 0.3 10.5 7.1 0.42 10.1 4.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin Mak16 PF04874.9 EKG09780.1 - 1.4 9.0 12.2 2.3 8.3 8.5 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region Nop14 PF04147.7 EKG09780.1 - 1.8 6.3 6.6 2.7 5.8 4.6 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EKG09780.1 - 2.7 7.1 4.2 3.4 6.8 2.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EKG09780.1 - 8.8 4.9 11.9 13 4.4 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PALP PF00291.20 EKG09781.1 - 6.3e-74 248.9 1.5 8.2e-74 248.5 1.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EKG09781.1 - 1.9e-47 158.7 0.0 4.1e-25 87.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Reo_P9 PF06043.6 EKG09781.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Reovirus P9-like family MFS_1 PF07690.11 EKG09782.1 - 4e-17 61.9 26.9 4.7e-16 58.4 14.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.9 EKG09783.1 - 8.8e-24 82.8 4.4 1.2e-13 50.4 0.7 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF1290 PF06947.7 EKG09783.1 - 1.7 8.6 6.0 0.97 9.3 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1290) p450 PF00067.17 EKG09784.1 - 0.00034 19.2 0.0 0.00056 18.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Mitofilin PF09731.4 EKG09785.1 - 3.9e-142 474.8 23.9 1.4e-119 400.4 18.6 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein AMP-binding_C_2 PF14535.1 EKG09785.1 - 0.15 12.1 2.1 0.62 10.1 0.0 2.6 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain Syja_N PF02383.13 EKG09786.1 - 6.3e-82 274.8 0.1 8e-82 274.5 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.17 EKG09787.1 - 1e-58 197.2 0.1 1.2e-58 197.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG09787.1 - 4.7e-20 72.2 0.0 8.1e-20 71.4 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EKG09787.1 - 1.6e-14 53.5 0.0 1.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG09787.1 - 1.4e-07 31.1 0.0 2.5e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKG09787.1 - 5e-07 29.0 0.0 5.9e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKG09787.1 - 7.2e-06 25.9 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Shikimate_DH PF01488.15 EKG09787.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA_22 PF13401.1 EKG09787.1 - 0.016 15.3 0.0 0.85 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 EKG09787.1 - 0.021 14.8 0.7 0.094 12.6 0.5 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EKG09787.1 - 0.032 13.4 0.2 0.13 11.4 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 DPPIV_N PF00930.16 EKG09787.1 - 0.065 11.8 0.0 0.08 11.5 0.0 1.1 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region SRPRB PF09439.5 EKG09787.1 - 0.075 12.2 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EKG09787.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Amidase02_C PF12123.3 EKG09787.1 - 0.14 11.8 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Amidase PF01425.16 EKG09788.1 - 3.4e-70 237.1 0.3 9.2e-69 232.3 0.2 2.0 1 1 0 1 1 1 1 Amidase SUR7 PF06687.7 EKG09789.1 - 2.2e-44 151.5 12.7 2.6e-44 151.3 8.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Rad4 PF03835.10 EKG09790.1 - 1.8e-14 53.3 2.9 2.6e-14 52.8 1.6 1.5 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EKG09790.1 - 2.1e-12 47.2 2.2 5.2e-12 45.9 1.2 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily WD40 PF00400.27 EKG09791.1 - 1.2e-09 37.6 4.9 0.18 11.7 0.0 8.1 9 0 0 9 9 9 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EKG09791.1 - 7.7e-08 32.0 0.5 6e-05 22.6 0.2 3.1 3 1 0 3 3 3 2 PQQ-like domain Sigma70_ner PF04546.8 EKG09791.1 - 2.9 7.4 7.8 0.11 12.1 0.6 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Cyclin_N PF00134.18 EKG09792.1 - 3.8e-37 126.6 0.4 6.8e-37 125.8 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EKG09792.1 - 1.5e-13 50.6 1.6 6.1e-13 48.7 1.1 2.0 1 1 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_S64 PF08192.6 EKG09794.1 - 0.0025 16.2 0.3 0.017 13.5 0.2 2.1 1 1 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.8 EKG09794.1 - 0.0068 15.4 0.2 0.01 14.8 0.2 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.1 EKG09794.1 - 0.1 12.5 0.0 0.53 10.2 0.0 2.2 1 1 0 1 1 1 0 Trypsin-like peptidase domain Ribosomal_S5 PF00333.15 EKG09795.1 - 3e-28 97.3 2.0 3e-28 97.3 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EKG09795.1 - 3.9e-21 74.0 0.1 3.9e-21 74.0 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain FXR1P_C PF12235.3 EKG09795.1 - 1.4 8.9 8.4 2.5 8.2 5.8 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Metallophos PF00149.23 EKG09796.1 - 2.4e-40 138.0 0.2 3.3e-40 137.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aldedh PF00171.17 EKG09797.1 - 2.1e-187 623.0 0.6 2.4e-187 622.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Candida_ALS PF05792.8 EKG09798.1 - 3.3e-08 33.5 86.2 0.0001 22.3 5.3 77.0 78 4 1 79 79 79 38 Candida agglutinin-like (ALS) Biotin_lipoyl_2 PF13533.1 EKG09798.1 - 0.15 11.7 17.6 14 5.4 0.1 8.2 9 0 0 9 9 9 0 Biotin-lipoyl like NmrA PF05368.8 EKG09799.1 - 4.9e-19 68.5 0.0 6.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG09799.1 - 2.5e-13 50.4 0.3 4.4e-13 49.6 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG09799.1 - 2.7e-06 27.0 0.1 5.8e-06 25.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG09799.1 - 0.0046 15.7 0.0 0.0066 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EKG09799.1 - 0.021 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4398 PF14346.1 EKG09799.1 - 0.23 11.5 1.7 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Iso_dh PF00180.15 EKG09801.1 - 1.7e-76 257.4 0.5 3.8e-76 256.2 0.4 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.6 EKG09801.1 - 0.15 11.8 2.1 0.16 11.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1447) UvrD_C PF13361.1 EKG09802.1 - 7.7e-76 255.8 0.0 1.2e-75 255.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EKG09802.1 - 9.7e-62 209.0 0.5 6.4e-59 199.7 0.4 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EKG09802.1 - 4.8e-14 52.3 0.0 1.5e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EKG09802.1 - 4.1e-10 39.2 0.2 1.6e-09 37.4 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKG09802.1 - 1.2e-06 28.2 0.0 2e-05 24.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG09802.1 - 0.0018 17.9 0.1 0.0076 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKG09802.1 - 0.0024 18.0 0.2 0.36 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EKG09802.1 - 0.026 13.9 0.0 0.75 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Inhibitor_I34 PF10466.4 EKG09803.1 - 0.14 12.2 0.5 0.71 9.9 0.1 2.2 2 1 0 2 2 2 0 Saccharopepsin inhibitor I34 PA14_2 PF10528.4 EKG09805.1 - 5.2e-41 139.1 12.2 3.9e-26 91.2 2.7 2.8 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.7 EKG09805.1 - 9.9e-11 41.4 1.0 9.8e-05 22.0 0.1 2.5 2 0 0 2 2 2 2 PA14 domain Myb_DNA-bind_4 PF13837.1 EKG09807.1 - 0.0056 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Lactamase_B_2 PF12706.2 EKG09808.1 - 3.1e-25 88.8 0.0 3.9e-24 85.2 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG09808.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG09808.1 - 0.004 16.8 0.3 0.016 14.8 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Pho88 PF10032.4 EKG09809.1 - 4e-82 274.1 0.0 4.5e-82 273.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Myb_DNA-binding PF00249.26 EKG09810.1 - 5.3e-12 45.5 0.0 2.6e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG09810.1 - 9e-05 22.4 0.0 0.041 13.9 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.12 EKG09811.1 - 9.5e-146 484.5 0.0 1.1e-145 484.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EKG09811.1 - 0.023 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Carbamoyltransferase MORN PF02493.15 EKG09812.1 - 1.7e-15 55.7 14.4 2.2e-06 27.0 0.2 4.6 4 0 0 4 4 4 4 MORN repeat zf-C3HC4_3 PF13920.1 EKG09812.1 - 1.6e-12 46.8 5.9 1.6e-12 46.8 4.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UCH PF00443.24 EKG09812.1 - 6e-12 45.2 1.1 9.1e-12 44.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EKG09812.1 - 2.1e-09 37.0 0.0 2.1e-09 37.0 0.0 2.2 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.21 EKG09812.1 - 1.5e-05 25.2 0.0 0.0037 17.4 0.0 2.6 2 0 0 2 2 2 1 MATH domain zf-C3HC4_2 PF13923.1 EKG09812.1 - 0.00067 19.6 6.6 0.00067 19.6 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG09812.1 - 0.0018 17.9 8.3 0.024 14.3 3.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EKG09812.1 - 0.14 11.7 4.7 0.13 11.7 2.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 EKG09812.1 - 0.19 11.3 8.8 0.55 9.9 3.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) D123 PF07065.9 EKG09813.1 - 0.031 13.3 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 D123 Sugar_tr PF00083.19 EKG09814.1 - 1.2e-129 432.7 25.2 1.4e-129 432.6 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG09814.1 - 9.6e-24 83.7 22.5 9.6e-24 83.7 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MSP1b PF03429.8 EKG09814.1 - 0.089 10.6 0.3 0.14 10.0 0.2 1.2 1 0 0 1 1 1 0 Major surface protein 1B Toxin_44 PF15523.1 EKG09815.1 - 2.5 8.0 8.1 0.65 9.9 2.0 2.3 1 1 1 2 2 2 0 Putative toxin 44 Pectate_lyase PF03211.8 EKG09817.1 - 1.1e-65 221.1 5.7 1.3e-65 220.8 3.9 1.0 1 0 0 1 1 1 1 Pectate lyase Arylsulfotran_2 PF14269.1 EKG09819.1 - 1.9e-51 175.0 0.0 2.5e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EKG09819.1 - 8.9e-12 44.2 0.1 1.7e-10 40.0 0.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Cache_1 PF02743.13 EKG09819.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Cache domain PSK PF06404.7 EKG09820.1 - 1.2e-09 38.7 7.1 0.00044 20.9 0.1 3.3 3 0 0 3 3 3 3 Phytosulfokine precursor protein (PSK) SmpA_OmlA PF04355.8 EKG09820.1 - 0.073 12.7 3.6 15 5.2 0.5 3.0 1 1 1 2 2 2 0 SmpA / OmlA family RRM_1 PF00076.17 EKG09823.1 - 4.9e-18 64.5 0.2 9.3e-18 63.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG09823.1 - 2.3e-13 49.8 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG09823.1 - 2e-09 37.1 0.2 2.7e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JmjC PF02373.17 EKG09824.1 - 5.6e-09 36.2 0.2 2.7e-08 34.0 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EKG09824.1 - 2.1e-08 33.7 6.2 2.1e-08 33.7 4.3 2.3 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.1 EKG09824.1 - 5.1e-07 29.4 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.1 EKG09824.1 - 0.87 8.9 6.9 0.89 8.9 3.3 2.3 2 0 0 2 2 2 0 PHD-finger DUF1423 PF07227.6 EKG09824.1 - 0.96 8.0 1.8 1.6 7.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) zf-PHD-like PF15446.1 EKG09824.1 - 1 8.6 7.6 0.11 11.8 1.5 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PYNP_C PF07831.8 EKG09825.1 - 7.3e-17 60.5 1.0 2e-16 59.1 0.1 2.2 3 0 0 3 3 3 1 Pyrimidine nucleoside phosphorylase C-terminal domain Glycos_transf_3 PF00591.16 EKG09825.1 - 0.0035 16.7 1.0 0.0046 16.3 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain BON PF04972.12 EKG09825.1 - 0.13 12.0 0.3 0.13 12.0 0.2 2.1 2 0 0 2 2 2 0 BON domain SAC3_GANP PF03399.11 EKG09826.1 - 4.9e-27 94.8 0.0 7e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EKG09826.1 - 1.5e-22 79.9 0.0 2.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RmuC PF02646.11 EKG09826.1 - 0.13 11.0 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 RmuC family Ribosomal_L11 PF00298.14 EKG09827.1 - 5.2e-17 61.7 1.8 2e-16 59.8 1.3 1.9 1 1 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EKG09827.1 - 3.4e-08 32.8 0.0 6.7e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain PEP_mutase PF13714.1 EKG09828.1 - 1.7e-47 161.6 0.4 2.2e-47 161.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EKG09828.1 - 1.7e-18 66.1 0.4 2.6e-18 65.5 0.3 1.2 1 0 0 1 1 1 1 Isocitrate lyase family AMP-binding PF00501.23 EKG09829.1 - 4.1e-81 272.5 0.0 5.8e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG09829.1 - 1.9e-14 54.3 0.2 5.7e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EKG09829.1 - 0.0078 14.7 0.0 0.028 12.9 0.0 1.7 2 0 0 2 2 2 1 GH3 auxin-responsive promoter DUF2975 PF11188.3 EKG09830.1 - 0.072 12.8 0.8 11 5.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) MFS_1 PF07690.11 EKG09831.1 - 0.00018 20.3 4.8 0.00018 20.3 3.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG09831.1 - 0.0033 16.0 3.9 0.0059 15.2 2.7 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter EIIBC-GUT_C PF07663.6 EKG09831.1 - 0.087 12.9 3.6 0.48 10.5 0.1 2.8 2 1 1 3 3 3 0 Sorbitol phosphotransferase enzyme II C-terminus DUF161 PF02588.10 EKG09831.1 - 0.22 11.8 6.7 2 8.7 0.0 3.0 2 1 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 p450 PF00067.17 EKG09832.1 - 3.4e-57 193.9 0.0 3.9e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EKG09833.1 - 2.9e-25 88.6 0.0 5.2e-17 61.4 0.0 2.3 2 1 0 2 2 2 2 Transferase family ELO PF01151.13 EKG09835.1 - 7.5e-62 208.8 19.7 9.3e-62 208.5 13.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ank PF00023.25 EKG09836.1 - 8.3e-21 72.7 0.0 3.6e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EKG09836.1 - 5.7e-18 65.0 0.0 8.4e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG09836.1 - 2e-13 50.0 0.1 4.5e-08 33.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG09836.1 - 1.7e-12 46.2 0.0 3.2e-05 23.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EKG09836.1 - 4.6e-11 42.9 0.0 8.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF1590 PF07629.6 EKG09836.1 - 0.04 13.5 1.1 4.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) PLA2_B PF01735.13 EKG09838.1 - 1e-159 531.8 3.2 1.2e-159 531.6 2.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ribonuclease PF00545.15 EKG09840.1 - 3.7e-05 23.7 0.1 6.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ribonuclease DUF1925 PF09094.6 EKG09840.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) Crystall PF00030.14 EKG09841.1 - 0.0092 15.8 0.2 0.049 13.5 0.1 1.9 2 0 0 2 2 2 1 Beta/Gamma crystallin Thioredoxin PF00085.15 EKG09842.1 - 8e-62 205.4 0.0 1.6e-31 108.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EKG09842.1 - 1.1e-20 74.0 0.2 2.7e-20 72.7 0.2 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EKG09842.1 - 1.4e-18 67.1 0.0 1.6e-08 34.6 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EKG09842.1 - 9.6e-13 47.9 0.0 4.4e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EKG09842.1 - 9e-12 44.9 0.0 0.00022 21.3 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 EKG09842.1 - 6.3e-07 29.0 0.5 0.0041 16.6 0.0 2.3 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 EKG09842.1 - 1.5e-06 28.1 0.0 0.00064 19.6 0.0 2.5 2 1 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 EKG09842.1 - 6.5e-06 25.7 0.0 0.0056 16.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin AhpC-TSA PF00578.16 EKG09842.1 - 7.3e-06 25.6 0.0 0.039 13.6 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.1 EKG09842.1 - 4.3e-05 23.3 0.3 0.14 11.9 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain TraF PF13728.1 EKG09842.1 - 0.00022 20.7 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 EKG09842.1 - 0.0011 18.7 0.0 0.25 11.1 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EKG09842.1 - 0.039 13.9 0.8 12 5.8 0.0 3.4 2 2 2 4 4 4 0 Thioredoxin Glutaredoxin PF00462.19 EKG09842.1 - 0.066 13.2 0.9 19 5.3 0.1 3.0 2 2 0 2 2 2 0 Glutaredoxin WD40 PF00400.27 EKG09843.1 - 5e-34 114.9 3.8 1.7e-09 37.1 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKG09843.1 - 0.11 12.2 0.0 2.4 7.9 0.0 3.2 4 2 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Ribonuc_red_sm PF00268.16 EKG09844.1 - 2.8e-122 407.1 1.4 3.3e-122 406.8 1.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain MFS_1 PF07690.11 EKG09845.1 - 1.2e-28 99.8 29.8 1.4e-28 99.6 20.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG09845.1 - 4.3e-08 32.1 20.1 0.00014 20.5 1.4 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EKG09845.1 - 4.4e-08 31.9 18.2 9.5e-07 27.5 5.3 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EKG09845.1 - 3.9e-05 23.3 3.0 0.23 11.2 0.0 3.2 3 0 0 3 3 3 2 MFS_1 like family ADH_zinc_N PF00107.21 EKG09846.1 - 1.3e-19 70.0 0.6 1.2e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1798 PF08807.5 EKG09847.1 - 0.089 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) LDB19 PF13002.2 EKG09848.1 - 0.016 14.7 0.0 0.017 14.6 0.0 1.1 1 0 0 1 1 1 0 Arrestin_N terminal like zf-C2H2_4 PF13894.1 EKG09849.1 - 4.6e-06 26.5 11.7 0.047 14.0 0.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG09849.1 - 0.0091 16.2 15.3 0.075 13.4 0.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type DivIC PF04977.10 EKG09849.1 - 0.027 13.9 0.1 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Prefoldin_2 PF01920.15 EKG09849.1 - 0.19 11.5 1.9 0.5 10.1 1.3 1.7 2 0 0 2 2 2 0 Prefoldin subunit zf-H2C2_5 PF13909.1 EKG09849.1 - 0.38 11.0 3.4 10 6.5 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain CarbpepA_inh PF02977.10 EKG09849.1 - 0.71 9.5 5.6 0.3 10.7 1.5 2.1 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor TIP120 PF08623.5 EKG09851.1 - 3.6e-61 205.6 0.1 2.4e-60 202.9 0.1 2.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EKG09851.1 - 2.7e-14 53.2 10.4 0.044 14.0 0.0 8.2 10 1 0 10 10 10 4 HEAT repeats HEAT PF02985.17 EKG09851.1 - 2.4e-11 42.6 4.0 0.026 14.5 0.0 8.6 7 0 0 7 7 7 2 HEAT repeat DUF2435 PF10363.4 EKG09851.1 - 1.3e-06 28.2 1.2 0.3 11.0 0.0 4.8 5 0 0 5 5 5 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EKG09851.1 - 5.5e-06 26.6 25.3 36 5.0 0.0 12.6 12 3 1 13 13 13 0 HEAT-like repeat Adaptin_N PF01602.15 EKG09851.1 - 8.2e-05 21.1 0.1 9.1 4.4 0.0 5.3 5 2 0 5 5 5 3 Adaptin N terminal region Cnd1 PF12717.2 EKG09851.1 - 0.0068 16.2 0.1 6.4 6.5 0.0 4.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EKG09851.1 - 0.12 12.2 0.9 28 4.7 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EKG09851.1 - 0.13 11.0 11.2 1.4 7.5 1.8 5.2 6 1 1 7 7 7 0 RNAPII transcription regulator C-terminal PLAC8 PF04749.12 EKG09852.1 - 7.9e-09 36.0 7.9 1.2e-08 35.4 5.5 1.2 1 0 0 1 1 1 1 PLAC8 family Isochorismatase PF00857.15 EKG09853.1 - 9.1e-08 32.2 0.0 1.4e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family NPP1 PF05630.6 EKG09854.1 - 3.5e-42 144.4 0.1 3.9e-42 144.3 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF500 PF04366.7 EKG09855.1 - 8.1e-45 151.3 0.6 1.3e-44 150.6 0.1 1.5 2 0 0 2 2 2 1 Family of unknown function (DUF500) DLH PF01738.13 EKG09856.1 - 2.6e-25 89.0 0.1 2.9e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG09856.1 - 5.2e-06 26.2 0.0 7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_2 PF00890.19 EKG09857.1 - 1.9e-36 125.8 0.0 2.7e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG09857.1 - 0.00072 18.5 1.8 0.02 13.8 1.3 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG09857.1 - 0.00099 19.0 0.0 0.027 14.3 0.0 2.8 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NUMOD1 PF07453.8 EKG09857.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 NUMOD1 domain DUF386 PF04074.7 EKG09857.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF386) Abhydrolase_6 PF12697.2 EKG09858.1 - 2.5e-29 102.7 0.3 4.7e-29 101.8 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG09858.1 - 7.1e-10 38.8 0.2 1.6e-09 37.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG09858.1 - 3.4e-05 23.5 0.0 6.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EKG09858.1 - 0.004 16.7 0.0 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Condensation PF00668.15 EKG09860.1 - 6.1e-223 737.8 0.1 7.9e-41 139.8 0.0 8.0 6 2 0 6 6 6 6 Condensation domain AMP-binding PF00501.23 EKG09860.1 - 8.3e-207 686.5 0.4 1e-95 320.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme PP-binding PF00550.20 EKG09860.1 - 9.9e-56 185.9 4.1 3.1e-10 40.1 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG09860.1 - 6.3e-12 46.2 4.4 0.0019 19.1 0.1 5.2 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EKG09860.1 - 0.0088 14.6 2.9 9.9 4.5 0.0 4.1 5 0 0 5 5 5 2 GH3 auxin-responsive promoter AATase PF07247.7 EKG09860.1 - 1.5 7.2 0.1 45 2.4 0.0 2.7 2 0 0 2 2 2 0 Alcohol acetyltransferase ABC_membrane PF00664.18 EKG09861.1 - 2.2e-75 253.6 33.7 7.1e-41 140.4 11.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EKG09861.1 - 2.4e-69 231.9 0.0 1.4e-33 116.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKG09861.1 - 1.5e-12 47.2 0.1 0.0033 16.6 0.1 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG09861.1 - 3.2e-12 47.0 0.0 0.038 13.9 0.0 4.1 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EKG09861.1 - 1.5e-09 37.2 0.3 0.00067 19.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG09861.1 - 1.1e-08 35.2 9.4 0.00076 19.5 0.3 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EKG09861.1 - 1.9e-08 35.1 0.0 0.0072 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EKG09861.1 - 3.1e-08 32.6 0.1 0.011 14.4 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 EKG09861.1 - 1.6e-07 31.5 0.2 0.065 13.3 0.1 3.6 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EKG09861.1 - 6.5e-07 28.6 0.0 0.017 14.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKG09861.1 - 2.5e-06 27.0 0.3 0.13 11.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EKG09861.1 - 1.3e-05 24.9 0.9 0.15 11.6 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EKG09861.1 - 2.2e-05 24.0 0.7 0.11 11.9 0.0 3.2 4 0 0 4 4 3 2 AAA-like domain AAA_33 PF13671.1 EKG09861.1 - 2.6e-05 24.1 0.0 0.36 10.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EKG09861.1 - 8.8e-05 22.8 0.0 0.65 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EKG09861.1 - 0.00011 22.4 0.1 4 7.6 0.1 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EKG09861.1 - 0.00015 21.7 0.0 0.056 13.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 MobB PF03205.9 EKG09861.1 - 0.00056 19.6 0.1 0.34 10.6 0.0 3.3 4 0 0 4 4 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EKG09861.1 - 0.00079 19.2 3.3 1.3 9.0 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 EKG09861.1 - 0.0014 18.3 0.0 0.89 9.2 0.0 3.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.9 EKG09861.1 - 0.0017 18.1 0.0 2.1 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EKG09861.1 - 0.0021 18.4 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EKG09861.1 - 0.0059 16.1 0.0 0.45 10.0 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF3987 PF13148.1 EKG09861.1 - 0.007 14.9 0.1 2.5 6.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_28 PF13521.1 EKG09861.1 - 0.0095 15.9 0.2 3.6 7.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EKG09861.1 - 0.0095 15.0 0.2 6.5 5.7 0.0 3.6 4 0 0 4 4 4 0 Zeta toxin NACHT PF05729.7 EKG09861.1 - 0.014 15.0 0.1 1.6 8.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.10 EKG09861.1 - 0.053 12.1 0.0 3 6.4 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 EKG09861.1 - 0.086 12.7 0.0 8.7 6.3 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EKG09861.1 - 0.094 12.8 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EKG09861.1 - 0.11 12.3 0.0 15 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EKG09861.1 - 0.25 10.9 0.0 13 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EKG09861.1 - 0.6 8.7 0.0 7.3 5.1 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit NusB PF01029.13 EKG09862.1 - 0.0045 16.9 0.0 7.3 6.5 0.0 3.0 1 1 2 3 3 3 2 NusB family MgtE_N PF03448.12 EKG09862.1 - 0.03 14.6 1.3 8.5 6.7 0.0 2.8 1 1 2 3 3 3 0 MgtE intracellular N domain DUF1939 PF09154.5 EKG09862.1 - 0.13 12.2 0.1 65 3.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1939) DUF3328 PF11807.3 EKG09863.1 - 4.1e-25 88.7 1.6 5.4e-25 88.3 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) COesterase PF00135.23 EKG09864.1 - 1e-93 314.9 0.0 1.3e-93 314.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG09864.1 - 1e-09 38.2 0.2 4.4e-09 36.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG09864.1 - 0.00021 21.0 0.1 0.00039 20.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG09864.1 - 0.022 13.9 0.0 0.052 12.7 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 EKG09865.1 - 1.7e-13 50.0 29.2 5.9e-12 44.9 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1183 PF06682.7 EKG09866.1 - 1.1e-62 212.4 0.0 1.4e-62 212.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) PIG-X PF08320.7 EKG09867.1 - 5.6e-62 208.7 0.0 8.3e-62 208.1 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 ThiF PF00899.16 EKG09868.1 - 3.6e-16 59.2 0.0 6.5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family SAC3_GANP PF03399.11 EKG09870.1 - 2.4e-44 151.3 0.0 4.3e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2841 PF11001.3 EKG09871.1 - 2.4e-27 95.2 1.7 5.8e-27 94.0 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) ABC_membrane PF00664.18 EKG09872.1 - 5.6e-81 271.9 32.6 2.1e-47 161.8 5.1 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EKG09872.1 - 1e-48 165.1 0.0 7.8e-29 100.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKG09872.1 - 7.1e-09 35.2 3.3 0.011 14.9 0.1 4.1 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EKG09872.1 - 9.7e-07 28.9 1.0 0.016 15.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EKG09872.1 - 8.1e-06 25.7 0.1 0.24 11.3 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EKG09872.1 - 4.7e-05 23.4 0.1 3.4 7.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.1 EKG09872.1 - 8.2e-05 22.0 0.1 0.17 11.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKG09872.1 - 9.8e-05 21.8 0.1 0.3 10.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EKG09872.1 - 0.00022 20.4 0.2 0.037 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EKG09872.1 - 0.00065 20.1 0.4 1.7 9.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EKG09872.1 - 0.0036 17.6 0.1 0.3 11.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EKG09872.1 - 0.018 13.9 0.1 0.4 9.5 0.0 2.5 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EKG09872.1 - 0.019 14.0 0.1 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 EKG09872.1 - 0.02 14.7 1.2 0.74 9.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Dynamin_N PF00350.18 EKG09872.1 - 0.026 14.3 2.9 0.66 9.7 0.2 2.5 2 0 0 2 2 2 0 Dynamin family ATP-synt_ab PF00006.20 EKG09872.1 - 0.046 13.2 0.3 0.17 11.3 0.0 2.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EKG09872.1 - 0.054 12.9 0.0 13 5.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EKG09872.1 - 0.13 12.4 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 EKG09872.1 - 0.17 11.3 0.0 1.2 8.5 0.0 2.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EKG09872.1 - 0.23 11.0 3.1 3.7 7.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EKG09872.1 - 0.47 9.8 2.5 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 EKG09872.1 - 0.79 9.8 4.4 7.5 6.6 0.2 3.2 2 1 0 2 2 2 0 AAA domain DUF4164 PF13747.1 EKG09873.1 - 0.69 10.0 6.9 4.8 7.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Pet127 PF08634.5 EKG09874.1 - 5.9e-115 383.1 0.6 8.6e-115 382.5 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 LRR_6 PF13516.1 EKG09875.1 - 0.0092 15.9 4.7 18 5.7 0.3 5.9 6 0 0 6 6 6 1 Leucine Rich repeat PH PF00169.24 EKG09875.1 - 0.091 12.9 0.4 0.43 10.8 0.3 2.1 1 1 0 1 1 1 0 PH domain MIF4G_like PF09088.6 EKG09876.1 - 2.9e-77 258.4 0.6 6e-77 257.4 0.4 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EKG09876.1 - 3.2e-52 177.2 0.0 4.9e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EKG09876.1 - 4.3e-10 39.3 0.1 3.4e-09 36.4 0.0 2.4 3 0 0 3 3 3 1 MIF4G domain DUF3349 PF11829.3 EKG09876.1 - 0.021 15.2 0.5 0.3 11.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Pkinase PF00069.20 EKG09877.1 - 4.1e-65 219.5 0.0 4.9e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09877.1 - 4.6e-25 88.1 0.0 6.1e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG09877.1 - 5.6e-07 28.8 0.0 1.7e-06 27.2 0.0 1.7 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EKG09877.1 - 0.0011 18.8 0.1 0.0044 16.7 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKG09877.1 - 0.051 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 EKG09877.1 - 0.053 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sad1_UNC PF07738.8 EKG09878.1 - 7e-36 122.9 0.1 1.2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Macoilin PF09726.4 EKG09878.1 - 0.0024 16.2 14.7 0.0055 15.0 10.2 1.5 1 0 0 1 1 1 1 Transmembrane protein Pkinase PF00069.20 EKG09879.1 - 6.3e-64 215.6 0.0 1.1e-63 214.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09879.1 - 4.7e-29 101.2 0.0 6.7e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG09879.1 - 0.0093 14.9 0.2 0.043 12.7 0.0 2.2 3 1 0 3 3 3 1 Kinase-like TGT PF01702.13 EKG09879.1 - 0.064 12.5 0.4 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase Pkinase PF00069.20 EKG09880.1 - 9.3e-61 205.2 0.0 1.7e-60 204.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09880.1 - 7.7e-37 126.7 0.0 2.7e-34 118.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKG09880.1 - 9.3e-08 31.3 0.0 1.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKG09880.1 - 0.0038 16.9 0.2 0.01 15.5 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 EKG09881.1 - 8.3e-27 93.6 0.0 1e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EKG09881.1 - 0.022 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region CobW_C PF07683.9 EKG09882.1 - 5.1e-21 74.1 0.5 1.6e-16 59.7 0.0 2.7 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain cobW PF02492.14 EKG09882.1 - 1.6e-10 40.7 0.1 2.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SDA1 PF05285.7 EKG09882.1 - 0.0043 16.3 16.1 0.011 15.0 11.4 1.3 1 1 0 1 1 1 1 SDA1 CDC45 PF02724.9 EKG09882.1 - 0.016 13.2 0.5 0.023 12.7 0.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TB2_DP1_HVA22 PF03134.14 EKG09883.1 - 1.1e-29 101.9 7.6 1.6e-29 101.5 5.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.10 EKG09884.1 - 1.1e-31 108.7 0.0 2.9e-31 107.4 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pept_tRNA_hydro PF01195.14 EKG09885.1 - 5.9e-12 45.4 0.0 1.8e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF605 PF04652.11 EKG09885.1 - 0.57 9.5 14.6 0.72 9.1 10.1 1.1 1 0 0 1 1 1 0 Vta1 like NmrA PF05368.8 EKG09886.1 - 3e-23 82.3 0.0 3.9e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG09886.1 - 3e-08 33.8 0.0 5.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EKG09886.1 - 3e-05 23.1 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EKG09886.1 - 6.6e-05 23.1 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EKG09886.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RNA_pol_I_A49 PF06870.7 EKG09888.1 - 3.1e-81 272.9 2.3 3.8e-81 272.6 1.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF123 PF01986.11 EKG09888.1 - 0.016 15.3 0.0 0.051 13.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF123 IncA PF04156.9 EKG09889.1 - 0.015 14.8 0.4 0.031 13.8 0.3 1.7 1 0 0 1 1 1 0 IncA protein Menin PF05053.8 EKG09889.1 - 0.27 9.3 9.9 0.37 8.9 6.9 1.1 1 0 0 1 1 1 0 Menin DUF2207 PF09972.4 EKG09889.1 - 0.33 9.4 3.0 0.5 8.8 2.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Scs3p PF10261.4 EKG09889.1 - 0.36 9.8 2.3 5.8 5.8 0.5 2.2 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM NfeD PF01957.13 EKG09889.1 - 0.53 10.4 6.8 0.93 9.6 4.7 1.4 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF1700 PF08006.6 EKG09889.1 - 1.1 8.5 6.1 1.9 7.7 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF2201_N PF13203.1 EKG09889.1 - 9 5.3 7.6 11 5.0 5.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain HET PF06985.6 EKG09890.1 - 6.5e-30 104.1 0.0 1.3e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) QRPTase_N PF02749.11 EKG09890.1 - 0.058 13.2 0.0 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF4246 PF14033.1 EKG09891.1 - 5.7e-169 562.9 5.5 2.9e-167 557.3 3.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EKG09891.1 - 0.018 15.3 0.1 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase UAA PF08449.6 EKG09893.1 - 6.5e-12 44.9 21.3 8.2e-12 44.6 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EKG09893.1 - 1.5e-10 40.8 7.5 1.5e-10 40.8 5.2 3.1 1 1 1 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EKG09893.1 - 0.0025 17.8 28.4 0.006 16.6 5.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 EKG09893.1 - 0.53 8.8 15.5 0.02 13.5 4.7 2.5 1 1 1 2 2 2 0 Phosphate transporter family Thioredoxin PF00085.15 EKG09894.1 - 2.7e-05 23.7 0.1 5.5e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin NOPS PF08075.6 EKG09894.1 - 0.21 12.0 1.2 1.4 9.4 0.0 2.3 1 1 1 2 2 2 0 NOPS (NUC059) domain GYF PF02213.11 EKG09895.1 - 1.4e-13 50.1 1.2 3e-13 49.1 0.9 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 EKG09896.1 - 3.8e-74 247.6 0.0 4.7e-74 247.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 R3H PF01424.17 EKG09897.1 - 1.4e-12 47.1 0.6 3.3e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 EKG09897.1 - 1e-05 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG09897.1 - 1.9e-05 24.2 0.1 4.5e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG09897.1 - 0.0045 16.7 0.1 0.0079 16.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.19 EKG09898.1 - 8.7e-22 77.0 0.1 1.1e-21 76.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKG09898.1 - 0.00032 20.7 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CinA PF02464.12 EKG09900.1 - 6e-34 116.7 0.9 6.7e-34 116.5 0.6 1.0 1 0 0 1 1 1 1 Competence-damaged protein Patatin PF01734.17 EKG09902.1 - 1.9e-20 73.6 0.0 6.8e-20 71.8 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase MOSC PF03473.12 EKG09903.1 - 5.5e-18 64.7 0.0 8.6e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EKG09903.1 - 7.2e-11 41.8 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Patatin PF01734.17 EKG09904.1 - 8.5e-28 97.6 0.0 1.5e-27 96.8 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase PPR_3 PF13812.1 EKG09906.1 - 4.7e-11 42.0 2.7 0.007 16.5 0.1 7.2 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EKG09906.1 - 8.5e-11 41.6 0.5 1.4 8.9 0.0 7.7 6 2 3 9 9 9 4 PPR repeat family PPR PF01535.15 EKG09906.1 - 4.2e-05 23.2 0.0 5.7 7.1 0.0 6.2 6 0 0 6 6 6 1 PPR repeat Ribosomal_S18 PF01084.15 EKG09907.1 - 2e-13 49.9 0.0 8.5e-13 47.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S18 NAD_binding_8 PF13450.1 EKG09908.1 - 1.8e-09 37.4 0.0 6.2e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EKG09908.1 - 7.7e-07 28.5 0.0 0.00018 20.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EKG09908.1 - 0.0002 21.4 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG09908.1 - 0.00038 19.4 0.0 0.24 10.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG09908.1 - 0.0021 17.9 0.0 0.054 13.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF1344 PF07076.6 EKG09908.1 - 0.0056 16.2 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1344) Thi4 PF01946.12 EKG09908.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EKG09908.1 - 0.014 15.1 0.2 1.3 8.8 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKG09908.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EKG09908.1 - 0.02 13.9 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG09908.1 - 0.045 12.2 0.0 0.16 10.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 EKG09908.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 EKG09908.1 - 0.17 10.7 0.4 0.71 8.7 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein TPT PF03151.11 EKG09909.1 - 7.9e-28 97.0 11.4 7.9e-28 97.0 7.9 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EKG09909.1 - 5.2e-08 32.1 19.1 1.4e-06 27.4 13.2 2.1 1 1 0 1 1 1 1 UAA transporter family OppC_N PF12911.2 EKG09909.1 - 0.0054 16.0 0.0 0.0054 16.0 0.0 2.6 3 0 0 3 3 3 1 N-terminal TM domain of oligopeptide transport permease C EamA PF00892.15 EKG09909.1 - 0.011 15.7 11.5 0.011 15.7 8.0 2.8 3 0 0 3 3 3 0 EamA-like transporter family DUF914 PF06027.7 EKG09909.1 - 0.35 9.6 13.3 1.2 7.8 9.2 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) WD40 PF00400.27 EKG09910.1 - 1e-42 142.4 13.8 3.4e-09 36.2 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EKG09910.1 - 5.4e-32 109.6 18.3 8.3e-32 109.0 12.7 1.3 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EKG09910.1 - 2e-06 27.6 0.3 0.00016 21.4 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EKG09910.1 - 0.011 13.9 0.0 0.49 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) PCI PF01399.22 EKG09911.1 - 3.3e-22 78.8 0.4 1.1e-21 77.1 0.0 2.1 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 EKG09911.1 - 0.0023 17.3 0.1 0.0046 16.3 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain Prefoldin_2 PF01920.15 EKG09911.1 - 0.0054 16.4 0.5 0.026 14.2 0.3 2.2 1 0 0 1 1 1 1 Prefoldin subunit TPR_12 PF13424.1 EKG09911.1 - 0.24 11.3 12.8 3.2 7.7 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKG09911.1 - 0.62 10.8 8.3 4.2 8.1 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG09911.1 - 1 10.2 9.5 6 7.8 0.0 5.2 6 1 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 EKG09911.1 - 2.3 8.4 5.7 4.1 7.6 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKG09911.1 - 4.1 8.0 6.5 4.8 7.8 0.0 4.4 6 1 0 6 6 6 0 Tetratricopeptide repeat HET PF06985.6 EKG09912.1 - 2.6e-19 69.7 0.0 6.6e-19 68.4 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_47 PF01532.15 EKG09913.1 - 2.1e-162 540.8 0.0 2.5e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GST_N_3 PF13417.1 EKG09914.1 - 4.2e-15 55.7 0.0 8.7e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EKG09914.1 - 1.4e-14 53.8 0.0 2.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EKG09914.1 - 2.4e-13 50.0 0.0 4.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG09914.1 - 2.3e-12 46.7 0.0 4.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG09914.1 - 2.2e-07 30.6 0.0 3.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG09914.1 - 0.00018 21.8 0.0 0.00027 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EKG09914.1 - 0.028 14.8 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain 2Fe-2S_thioredx PF01257.14 EKG09916.1 - 2.6e-22 78.9 0.1 3.3e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SBP_bac_7 PF03480.8 EKG09916.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Fungal_trans_2 PF11951.3 EKG09917.1 - 3.5e-13 48.9 1.6 4.9e-10 38.5 0.0 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG09917.1 - 4.7e-07 29.5 9.6 8.9e-07 28.7 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I PF00867.13 EKG09919.1 - 3e-31 107.3 0.4 7.8e-31 105.9 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EKG09919.1 - 1.7e-29 102.0 1.5 2e-29 101.8 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EKG09919.1 - 0.0001 22.4 1.0 0.00066 19.8 0.0 2.6 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 EKG09919.1 - 0.052 12.3 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Acyl-CoA_dh_1 PF00441.19 EKG09920.1 - 4.1e-23 82.1 0.5 6.2e-23 81.5 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EKG09920.1 - 1.4e-17 62.9 0.0 2.8e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EKG09920.1 - 2.1e-15 57.2 0.6 4.3e-15 56.2 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EKG09920.1 - 2.2e-07 31.1 0.5 3.6e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 EKG09921.1 - 2.7e-51 172.7 0.0 3e-51 172.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG09921.1 - 6.4e-05 22.7 0.0 7.4e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKG09921.1 - 0.0053 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EKG09921.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain EHN PF06441.7 EKG09923.1 - 3.6e-32 110.5 0.3 5.4e-32 110.0 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG09923.1 - 3e-06 27.2 0.4 6.2e-06 26.2 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG09923.1 - 1.5e-05 24.6 0.1 5.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1705 PF08019.7 EKG09926.1 - 2.3 7.7 9.0 0.96 8.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) Glyco_hydro_35 PF01301.14 EKG09927.1 - 2.2e-73 247.3 0.5 2.2e-73 247.3 0.3 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EKG09927.1 - 5.1e-52 175.8 0.1 1.2e-51 174.6 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EKG09927.1 - 3.2e-36 123.9 3.5 1e-19 70.8 0.0 3.7 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EKG09927.1 - 7.5e-25 86.1 0.2 1.4e-24 85.2 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF3678 PF12435.3 EKG09928.1 - 1.3 8.6 8.9 0.19 11.3 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) CorA PF01544.13 EKG09929.1 - 9.7e-19 67.4 0.1 9.7e-19 67.4 0.1 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Far-17a_AIG1 PF04750.9 EKG09929.1 - 0.23 10.6 1.4 0.36 9.9 1.0 1.2 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein TFIID_20kDa PF03847.8 EKG09930.1 - 7.1e-23 80.6 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A V_ATPase_I PF01496.14 EKG09930.1 - 6.5 4.4 6.9 10 3.7 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gti1_Pac2 PF09729.4 EKG09931.1 - 7.9e-50 169.0 7.9 7.1e-41 139.8 0.2 2.7 2 1 1 3 3 3 2 Gti1/Pac2 family Cyt-b5 PF00173.23 EKG09932.1 - 2.4e-15 56.0 0.1 2.7e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Retrotrans_gag PF03732.12 EKG09933.1 - 5.1e-06 26.4 0.4 5.1e-06 26.4 0.3 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF972 PF06156.8 EKG09933.1 - 0.0017 18.6 0.4 0.025 14.9 0.0 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF972) DivIC PF04977.10 EKG09933.1 - 0.042 13.3 1.2 0.11 11.9 0.8 1.6 1 0 0 1 1 1 0 Septum formation initiator PspA_IM30 PF04012.7 EKG09933.1 - 0.11 11.8 0.3 0.11 11.8 0.2 1.9 2 0 0 2 2 2 0 PspA/IM30 family IL6 PF00489.12 EKG09933.1 - 0.18 11.4 1.4 0.46 10.0 0.1 2.0 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family Filament PF00038.16 EKG09933.1 - 0.23 10.8 3.3 0.96 8.8 0.1 2.0 2 0 0 2 2 2 0 Intermediate filament protein Nnf1 PF03980.9 EKG09933.1 - 0.24 11.3 2.0 0.5 10.3 0.5 2.0 2 0 0 2 2 2 0 Nnf1 IncA PF04156.9 EKG09933.1 - 0.28 10.7 3.6 1.2 8.7 0.8 2.1 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 EKG09933.1 - 0.34 11.0 2.6 2.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.10 EKG09933.1 - 0.36 10.6 2.7 0.85 9.4 1.9 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Striatin PF08232.7 EKG09933.1 - 0.38 11.0 2.8 1.1 9.5 1.9 2.0 1 1 0 1 1 1 0 Striatin family Ank_2 PF12796.2 EKG09935.1 - 0.014 15.6 0.0 0.044 14.1 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 EKG09935.1 - 0.11 12.3 0.0 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat X8 PF07983.8 EKG09936.1 - 2.2e-17 63.3 2.5 3.4e-17 62.6 1.7 1.3 1 0 0 1 1 1 1 X8 domain Glyco_hydro_72 PF03198.9 EKG09936.1 - 4.2e-08 32.5 0.0 6.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase SKG6 PF08693.5 EKG09936.1 - 0.0066 15.7 0.8 0.014 14.6 0.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 EKG09936.1 - 0.016 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3435 PF11917.3 EKG09943.1 - 1.4e-39 136.0 8.1 1.8e-39 135.6 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2_4 PF13894.1 EKG09943.1 - 0.0067 16.6 2.5 0.77 10.2 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3435 PF11917.3 EKG09945.1 - 5.4e-20 71.5 10.9 5.9e-20 71.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Spectrin PF00435.16 EKG09945.1 - 1.7 9.0 7.3 1.7 9.0 1.6 2.1 2 0 0 2 2 2 0 Spectrin repeat rve PF00665.21 EKG09946.1 - 2.3e-19 69.6 0.1 5.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain UBN2 PF14223.1 EKG09946.1 - 5e-07 29.5 0.2 9.9e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EKG09946.1 - 5.3e-06 25.9 0.2 1.1e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 EKG09946.1 - 1.2e-05 24.8 0.1 3e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EKG09946.1 - 0.0088 15.5 0.0 0.029 13.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-RING_2 PF13639.1 EKG09948.1 - 0.0012 18.5 3.8 0.0028 17.4 2.6 1.7 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 EKG09948.1 - 0.11 12.1 3.9 0.21 11.2 2.7 1.5 1 0 0 1 1 1 0 PHD-finger DUF1272 PF06906.6 EKG09948.1 - 3.1 7.6 5.8 0.71 9.7 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Exo_endo_phos_2 PF14529.1 EKG09951.1 - 0.00046 19.7 0.0 0.00095 18.7 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Calcipressin PF04847.7 EKG09952.1 - 0.069 12.7 0.1 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Calcipressin GAS PF13851.1 EKG09953.1 - 0.047 12.8 0.1 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 EKG09953.1 - 0.21 11.6 4.3 3.2 7.7 0.6 2.2 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Pap_E4 PF02711.9 EKG09957.1 - 0.017 15.8 0.8 0.036 14.8 0.6 1.5 1 0 0 1 1 1 0 E4 protein DUF1272 PF06906.6 EKG09958.1 - 0.011 15.5 6.4 0.022 14.6 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_5 PF14634.1 EKG09958.1 - 0.55 10.0 13.3 0.73 9.6 8.6 1.7 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG09958.1 - 2.5 8.1 10.4 6.3 6.9 7.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG09958.1 - 3 7.5 10.3 9.1 6.0 7.1 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Jiv90 PF14901.1 EKG09958.1 - 4.8 7.2 7.7 4.1 7.4 3.8 2.0 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Methyltransf_12 PF08242.7 EKG09959.1 - 0.054 13.9 0.0 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MULE PF10551.4 EKG09961.1 - 2e-16 59.9 0.1 1.1e-15 57.5 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain FAR1 PF03101.10 EKG09961.1 - 5.9e-05 23.5 1.5 0.00015 22.1 1.0 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain Transposase_mut PF00872.13 EKG09961.1 - 0.00026 19.6 0.9 0.00095 17.8 0.1 1.9 2 0 0 2 2 2 1 Transposase, Mutator family DBD_Tnp_Mut PF03108.10 EKG09961.1 - 0.00077 18.9 0.4 0.14 11.7 0.3 3.0 1 1 0 1 1 1 1 MuDR family transposase AFT PF08731.6 EKG09961.1 - 0.024 14.8 0.6 0.07 13.3 0.4 1.8 1 0 0 1 1 1 0 Transcription factor AFT Pkinase PF00069.20 EKG09962.1 - 1.5e-20 73.4 0.0 2.1e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG09962.1 - 1.9e-14 53.3 0.0 3.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GTP_EFTU PF00009.22 EKG09963.1 - 7.7e-10 38.5 0.3 4e-07 29.6 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Ank_2 PF12796.2 EKG09964.1 - 2e-54 181.8 0.0 2.2e-14 53.5 0.0 7.0 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG09964.1 - 4e-43 145.0 2.1 4.5e-09 36.5 0.0 8.9 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG09964.1 - 2e-41 139.0 5.9 7.6e-08 32.3 0.2 9.4 2 2 8 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.25 EKG09964.1 - 3.6e-39 130.6 1.9 7.3e-05 22.3 0.0 12.0 12 0 0 12 12 12 6 Ankyrin repeat Ank_3 PF13606.1 EKG09964.1 - 6.1e-27 90.9 0.0 0.00079 19.4 0.0 11.2 12 0 0 12 12 12 4 Ankyrin repeat NACHT PF05729.7 EKG09964.1 - 2.8e-07 30.3 0.0 7.1e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 EKG09964.1 - 8.7e-05 22.4 0.1 0.00019 21.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_16 PF13191.1 EKG09964.1 - 9.1e-05 22.5 0.8 0.00089 19.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 EKG09964.1 - 0.0011 18.3 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NTPase_1 PF03266.10 EKG09964.1 - 0.006 16.3 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 NTPase KAP_NTPase PF07693.9 EKG09964.1 - 0.015 14.3 0.0 0.067 12.1 0.0 1.9 2 0 0 2 2 2 0 KAP family P-loop domain Abhydrolase_9 PF10081.4 EKG09964.1 - 0.026 13.2 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family AAA_22 PF13401.1 EKG09964.1 - 0.031 14.3 0.3 0.23 11.6 0.0 2.6 3 1 0 3 3 3 0 AAA domain AAA PF00004.24 EKG09964.1 - 0.14 12.4 0.0 0.71 10.0 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.8 EKG09964.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DDE_3 PF13358.1 EKG09966.1 - 8.2e-16 58.0 0.0 1.6e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_23 PF13384.1 EKG09966.1 - 0.003 17.1 0.0 0.034 13.8 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_29 PF13551.1 EKG09966.1 - 0.0069 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_21 PF13276.1 EKG09966.1 - 0.028 14.3 0.0 0.092 12.7 0.0 1.7 2 0 0 2 2 2 0 HTH-like domain HTH_33 PF13592.1 EKG09966.1 - 0.034 13.6 0.1 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix GerE PF00196.14 EKG09966.1 - 0.037 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_3 PF01381.17 EKG09966.1 - 0.052 13.4 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix zf-RING_2 PF13639.1 EKG09967.1 - 0.00027 20.7 6.9 0.00027 20.7 4.8 1.6 2 0 0 2 2 2 1 Ring finger domain zf-H2C2_2 PF13465.1 EKG09967.1 - 0.91 9.9 7.1 0.63 10.4 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C3HC4_3 PF13920.1 EKG09967.1 - 5.9 6.6 8.7 1.1 8.9 3.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG09967.1 - 9.8 6.0 13.3 0.66 9.7 5.5 1.9 2 0 0 2 2 2 0 zinc-RING finger domain EST1_DNA_bind PF10373.4 EKG09971.1 - 1.6e-12 47.2 0.2 4.4e-12 45.7 0.1 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain E3_binding PF02817.12 EKG09971.1 - 0.065 12.8 0.3 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 e3 binding domain RNase_H PF00075.19 EKG09972.1 - 2.1e-06 28.1 0.0 4.6e-06 26.9 0.0 1.6 2 0 0 2 2 2 1 RNase H JmjC PF02373.17 EKG09973.1 - 4.9e-23 81.5 0.0 1.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Glyco_hydro_61 PF03443.9 EKG09975.1 - 4.7e-05 23.3 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SnoaL_2 PF12680.2 EKG09975.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain DUF1996 PF09362.5 EKG09978.1 - 2.9e-39 135.1 0.1 3.5e-39 134.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) RWD PF05773.17 EKG09978.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain U5_2-snRNA_bdg PF10597.4 EKG09980.1 - 0.085 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 DUF848 PF05852.6 EKG09983.1 - 0.002 17.9 1.8 0.0031 17.3 1.3 1.4 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Spectrin PF00435.16 EKG09983.1 - 0.0064 16.7 1.5 0.011 15.9 1.0 1.4 1 1 0 1 1 1 1 Spectrin repeat Cob_adeno_trans PF01923.13 EKG09983.1 - 0.0092 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Cortex-I_coil PF09304.5 EKG09983.1 - 0.0098 15.9 1.5 0.013 15.4 1.0 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil GrpE PF01025.14 EKG09983.1 - 0.012 15.2 0.6 0.016 14.7 0.4 1.2 1 0 0 1 1 1 0 GrpE Syntaxin-6_N PF09177.6 EKG09983.1 - 0.017 15.5 0.3 0.035 14.5 0.2 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal XhlA PF10779.4 EKG09983.1 - 0.037 13.9 3.2 0.081 12.8 2.2 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Mnd1 PF03962.10 EKG09983.1 - 0.039 13.6 1.0 0.045 13.4 0.7 1.1 1 0 0 1 1 1 0 Mnd1 family Syntaxin PF00804.20 EKG09983.1 - 0.055 13.6 1.9 0.12 12.5 1.3 1.6 1 1 0 1 1 1 0 Syntaxin Selenoprotein_S PF06936.6 EKG09983.1 - 0.12 11.9 1.0 0.15 11.6 0.7 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) COG2 PF06148.6 EKG09983.1 - 0.12 12.2 0.2 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Myb_DNA-bind_6 PF13921.1 EKG09984.1 - 0.00045 20.2 0.2 0.00076 19.5 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG09984.1 - 0.0005 20.0 0.1 0.00089 19.2 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKG09984.1 - 0.11 12.4 0.9 0.35 10.8 0.6 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain WEMBL PF05701.6 EKG09985.1 - 1.1e-05 24.0 23.4 5.2e-05 21.9 5.9 2.0 1 1 1 2 2 2 2 Weak chloroplast movement under blue light TSC22 PF01166.13 EKG09985.1 - 0.0046 16.8 3.6 0.0046 16.8 2.5 2.3 2 0 0 2 2 2 1 TSC-22/dip/bun family DUF4294 PF14127.1 EKG09985.1 - 0.013 15.1 3.2 0.013 15.1 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4294) DivIC PF04977.10 EKG09985.1 - 0.037 13.5 16.6 0.078 12.4 4.5 2.9 2 1 1 3 3 3 0 Septum formation initiator Sec8_exocyst PF04048.9 EKG09985.1 - 0.14 11.7 7.0 1.9 8.0 0.6 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain NPV_P10 PF05531.7 EKG09985.1 - 0.25 11.6 5.6 0.56 10.4 0.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EKG09985.1 - 0.45 10.2 12.4 1.9 8.2 0.6 2.3 2 1 0 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.1 EKG09985.1 - 0.75 10.1 8.6 3.8 7.8 2.5 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Mnd1 PF03962.10 EKG09985.1 - 0.76 9.4 21.2 0.28 10.8 3.9 2.0 1 1 1 2 2 2 0 Mnd1 family Fzo_mitofusin PF04799.8 EKG09985.1 - 0.76 9.1 9.4 0.47 9.8 3.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region WXG100 PF06013.7 EKG09985.1 - 1.2 9.1 7.7 3 7.8 1.1 2.8 2 2 0 2 2 2 0 Proteins of 100 residues with WXG CorA PF01544.13 EKG09985.1 - 1.9 7.4 6.0 3.6 6.5 4.2 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Rootletin PF15035.1 EKG09985.1 - 2.1 8.2 20.0 4.4 7.2 1.7 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 EKG09985.1 - 2.4 5.8 11.7 4.5 4.9 8.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 EKG09985.1 - 3.1 7.5 25.4 0.096 12.4 3.2 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 EKG09985.1 - 3.4 7.6 20.6 15 5.5 14.3 1.8 1 1 0 1 1 1 0 Fez1 COG2 PF06148.6 EKG09985.1 - 3.8 7.3 11.1 6.7 6.5 2.5 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phlebovirus_NSM PF07246.6 EKG09985.1 - 4.2 6.4 7.8 2.1 7.4 0.4 2.2 1 1 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF4259 PF14078.1 EKG09985.1 - 4.7 7.7 8.6 1.1 9.7 3.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) DUF3584 PF12128.3 EKG09985.1 - 4.7 4.3 22.4 5.8 4.0 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 EKG09985.1 - 5.7 7.3 18.3 0.78 10.1 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Dzip-like_N PF13815.1 EKG09985.1 - 9.1 6.1 15.8 2.6 7.8 4.1 2.7 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal AsnC_trans_reg PF01037.16 EKG09990.1 - 0.058 13.1 0.2 0.49 10.1 0.0 2.5 1 1 1 2 2 2 0 AsnC family DUF3723 PF12520.3 EKG09992.1 - 7.1e-11 41.2 0.0 1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF3723 PF12520.3 EKG09993.1 - 1.7e-99 333.6 0.0 1.7e-99 333.6 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3723) Filament PF00038.16 EKG09993.1 - 0.1 12.0 52.8 0.11 11.8 25.2 2.8 1 1 1 2 2 2 0 Intermediate filament protein DUF3435 PF11917.3 EKG09994.1 - 7.7e-77 258.7 0.0 9.4e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) GED PF02212.13 EKG09995.1 - 1.9e-07 30.8 0.1 2.8e-07 30.3 0.1 1.3 1 0 0 1 1 1 1 Dynamin GTPase effector domain TCTP PF00838.12 EKG09995.1 - 0.032 14.2 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Translationally controlled tumour protein DUF2551 PF10826.3 EKG09995.1 - 0.069 13.0 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) Dynamin_M PF01031.15 EKG09996.1 - 5.1e-22 78.0 0.0 7.1e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region DUF2408 PF10303.4 EKG09996.1 - 0.054 13.6 0.2 0.092 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Memo PF01875.12 EKG09996.1 - 0.11 11.3 0.1 0.19 10.6 0.1 1.4 1 0 0 1 1 1 0 Memo-like protein Dynamin_N PF00350.18 EKG09997.1 - 2.5e-29 102.2 0.4 4.1e-29 101.5 0.3 1.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EKG09997.1 - 2.2e-05 24.3 0.2 0.00018 21.4 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG09997.1 - 0.00033 19.9 0.7 0.073 12.3 0.4 2.4 2 1 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 EKG09997.1 - 0.00085 19.8 0.1 0.0021 18.5 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EKG09997.1 - 0.031 13.3 0.5 0.73 8.9 0.1 2.2 2 0 0 2 2 2 0 AIG1 family SRPRB PF09439.5 EKG09997.1 - 0.053 12.7 0.1 8.3 5.5 0.0 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EKG09997.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FIST_C PF10442.4 EKG09999.1 - 0.035 14.0 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 FIST C domain DUF3328 PF11807.3 EKG10000.1 - 1.5e-22 80.3 5.5 1.8e-22 80.0 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cu_amine_oxid PF01179.15 EKG10001.1 - 4.8e-100 335.1 2.8 5.7e-100 334.9 1.9 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EKG10001.1 - 2.4e-34 117.0 0.4 5e-34 116.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EKG10001.1 - 0.0017 18.4 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Myb_DNA-binding PF00249.26 EKG10002.1 - 0.092 12.8 0.5 0.33 11.0 0.2 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG10002.1 - 0.12 12.5 0.6 0.24 11.5 0.1 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Beta-lactamase PF00144.19 EKG10007.1 - 1.2e-10 40.9 0.1 2e-10 40.2 0.1 1.3 1 1 0 1 1 1 1 Beta-lactamase Git3 PF11710.3 EKG10008.1 - 3.7e-10 39.7 10.0 6.1e-10 38.9 6.9 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EKG10008.1 - 4.8e-07 28.9 7.7 7.6e-07 28.3 5.4 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EKG10008.1 - 7.3e-07 28.5 5.2 1.1e-06 27.9 3.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPI2 PF06432.6 EKG10008.1 - 0.78 9.0 4.8 4.2 6.6 0.6 2.4 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Na_H_Exchanger PF00999.16 EKG10011.1 - 7.8e-54 182.6 23.2 1e-53 182.2 16.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RPE65 PF03055.10 EKG10012.1 - 2.7e-07 29.5 0.0 3.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.10 EKG10013.1 - 4.9e-47 160.6 0.0 5.4e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein APOC4 PF15119.1 EKG10013.1 - 0.057 13.3 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein C4 TFIID-18kDa PF02269.11 EKG10014.1 - 7.2e-25 86.6 0.1 1.6e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EKG10014.1 - 0.0094 15.9 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2849 PF11011.3 EKG10014.1 - 7.5 6.8 6.7 3.5 7.9 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2849) adh_short PF00106.20 EKG10015.1 - 2.9e-17 63.1 6.2 3.4e-17 62.8 1.9 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG10015.1 - 1.3e-05 24.9 0.6 2.1e-05 24.2 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG10015.1 - 0.00038 20.2 0.0 0.00069 19.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EKG10015.1 - 0.0016 18.1 0.1 0.005 16.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EKG10015.1 - 0.0062 16.5 0.2 0.0098 15.9 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG10015.1 - 0.068 12.6 0.2 0.11 11.8 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acyl_transf_3 PF01757.17 EKG10016.1 - 5.2e-24 84.7 32.4 7.4e-23 80.9 22.5 2.3 1 1 0 1 1 1 1 Acyltransferase family adh_short PF00106.20 EKG10018.1 - 1.1e-31 109.9 5.8 1.8e-31 109.2 4.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10018.1 - 6.3e-23 81.7 0.3 8.4e-23 81.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG10018.1 - 7.9e-16 58.2 3.9 1.7e-15 57.1 2.7 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EKG10018.1 - 0.0046 16.6 0.9 0.0074 15.9 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_PK PF05891.7 EKG10018.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Epimerase PF01370.16 EKG10018.1 - 0.071 12.5 0.1 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Cellulase PF00150.13 EKG10019.1 - 8e-09 35.1 0.1 3.8e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.17 EKG10020.1 - 4.3e-19 68.3 0.0 5.8e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MOSC PF03473.12 EKG10021.1 - 1.7e-19 69.5 0.0 2.7e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EKG10021.1 - 8.9e-18 64.1 0.0 1.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Peptidase_C1_2 PF03051.10 EKG10022.1 - 1.4e-159 531.3 0.0 1.7e-159 531.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EKG10022.1 - 1.7e-07 31.3 0.9 0.024 14.5 0.0 2.8 3 0 0 3 3 3 2 Papain family cysteine protease Ferritin_2 PF13668.1 EKG10024.1 - 4.6e-46 156.1 3.2 6.4e-46 155.6 2.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Glyco_transf_25 PF01755.12 EKG10025.1 - 3.8e-05 23.4 0.0 0.00057 19.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) GST_N_2 PF13409.1 EKG10026.1 - 3.1e-08 33.5 0.1 9.6e-08 31.9 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EKG10026.1 - 1.2e-07 31.8 0.0 3.1e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG10026.1 - 4.8e-06 26.3 0.0 9.3e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG10026.1 - 0.039 13.9 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG10026.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain 14-3-3 PF00244.15 EKG10027.1 - 3e-87 291.6 0.5 3.3e-87 291.4 0.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Retrotrans_gag PF03732.12 EKG10028.1 - 0.00048 20.1 0.1 0.00061 19.8 0.0 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein Macoilin PF09726.4 EKG10029.1 - 0.0025 16.2 1.2 0.003 15.9 0.8 1.0 1 0 0 1 1 1 1 Transmembrane protein Fer4_21 PF14697.1 EKG10030.1 - 6.4 6.7 10.1 0.068 13.0 1.7 1.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Condensation PF00668.15 EKG10031.1 - 8.3e-17 60.9 0.0 2e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 Condensation domain Slx4 PF09494.5 EKG10031.1 - 0.17 11.6 0.7 0.44 10.3 0.1 2.1 2 1 0 2 2 2 0 Slx4 endonuclease AMP-binding PF00501.23 EKG10032.1 - 6.5e-22 77.5 0.0 7e-22 77.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ketoacyl-synt_C PF02801.17 EKG10033.1 - 1.9e-10 40.5 0.0 4.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain AMP-binding PF00501.23 EKG10033.1 - 1.3e-06 27.0 0.0 1.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF3425 PF11905.3 EKG10034.1 - 2.1e-28 98.9 0.3 3.3e-28 98.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) adh_short PF00106.20 EKG10035.1 - 1.3e-12 47.9 0.3 2.3e-12 47.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10035.1 - 4.8e-06 26.5 0.0 6.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG10035.1 - 6.1e-05 22.7 1.7 0.0001 22.0 1.1 1.6 1 1 0 1 1 1 1 KR domain Rhodanese PF00581.15 EKG10036.1 - 2.6e-07 30.9 0.1 1.1e-06 28.9 0.0 1.9 1 1 0 1 1 1 1 Rhodanese-like domain DUF1680 PF07944.7 EKG10037.1 - 1.4e-07 30.2 0.0 2.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Seryl_tRNA_N PF02403.17 EKG10044.1 - 0.025 14.5 0.7 0.036 14.0 0.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1875 PF08961.5 EKG10047.1 - 0.012 14.9 0.8 0.012 14.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) HALZ PF02183.13 EKG10047.1 - 0.06 13.0 7.9 0.11 12.2 2.5 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 EKG10047.1 - 0.11 12.8 6.6 2.3 8.5 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3840 PF12944.2 EKG10047.1 - 4.5 7.1 6.0 8.7 6.2 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3840) Amidase PF01425.16 EKG10049.1 - 5.7e-64 216.5 3.5 1.3e-42 146.1 0.0 2.7 2 1 0 2 2 2 2 Amidase Orbi_VP5 PF00901.12 EKG10049.1 - 0.17 10.0 0.0 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Hydantoinase_A PF01968.13 EKG10050.1 - 8.5e-80 267.9 8.6 9.1e-79 264.5 2.3 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.9 EKG10050.1 - 1.7e-65 221.2 0.0 2.9e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydant_A_N PF05378.8 EKG10050.1 - 1.4e-47 161.4 0.7 3.3e-45 153.7 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EKG10050.1 - 0.083 11.1 5.1 1.5 7.0 0.3 2.7 3 0 0 3 3 3 0 MutL protein BcrAD_BadFG PF01869.15 EKG10050.1 - 0.13 11.4 2.1 1 8.6 0.4 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FMN_dh PF01070.13 EKG10052.1 - 1.2e-94 317.0 0.2 5.7e-50 170.1 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EKG10052.1 - 0.0046 15.9 0.3 0.023 13.5 0.0 2.2 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 EKG10052.1 - 0.015 14.3 0.0 1.2 7.9 0.0 2.2 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EKG10052.1 - 0.034 13.0 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase Met_asp_mut_E PF06368.6 EKG10052.1 - 0.061 11.4 0.1 0.092 10.9 0.1 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) PHP PF02811.14 EKG10052.1 - 0.086 12.6 0.1 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 PHP domain DUF4148 PF13663.1 EKG10052.1 - 5.5 6.9 6.0 16 5.4 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4148) GalP_UDP_transf PF01087.17 EKG10053.1 - 8.4e-69 231.2 0.3 2.7e-66 223.1 0.0 2.6 2 1 1 3 3 3 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EKG10053.1 - 2.5e-55 186.5 0.0 7e-55 185.0 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EKG10053.1 - 0.0092 16.5 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 HIT domain Yip1 PF04893.12 EKG10054.1 - 8.7e-14 51.3 10.9 1.4e-13 50.7 7.6 1.4 1 0 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.13 EKG10055.1 - 4.5e-18 65.4 1.1 8.8e-18 64.5 0.8 1.5 1 0 0 1 1 1 1 RanBP1 domain Peptidase_M1 PF01433.15 EKG10056.1 - 6.9e-75 252.5 0.0 9.6e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EKG10056.1 - 1.1e-42 144.9 0.0 2.2e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EKG10056.1 - 9.8e-19 67.6 0.1 2.2e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Synaptonemal_3 PF15191.1 EKG10056.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Synaptonemal complex central element protein 3 Peptidase_M64 PF09471.5 EKG10056.1 - 0.029 14.0 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M61 PF05299.7 EKG10056.1 - 0.059 13.3 2.5 0.37 10.7 1.7 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF2063 PF09836.4 EKG10056.1 - 0.15 12.0 0.2 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) Tropomyosin_1 PF12718.2 EKG10058.1 - 0.004 16.9 18.3 0.058 13.2 9.2 2.6 2 0 0 2 2 2 1 Tropomyosin like TBPIP PF07106.8 EKG10058.1 - 0.0085 15.6 7.4 0.015 14.8 5.1 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EKG10058.1 - 0.17 11.4 13.6 0.38 10.3 9.4 1.5 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EKG10058.1 - 0.31 9.3 6.3 0.48 8.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ax_dynein_light PF10211.4 EKG10058.1 - 0.34 10.7 14.3 0.93 9.2 9.9 1.7 1 0 0 1 1 1 0 Axonemal dynein light chain DUF972 PF06156.8 EKG10058.1 - 0.53 10.6 12.3 0.24 11.7 6.6 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 EKG10058.1 - 0.81 8.6 11.1 1.3 7.9 7.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Tnp_P_element PF12017.3 EKG10058.1 - 0.88 8.7 3.5 1.4 8.0 2.4 1.3 1 0 0 1 1 1 0 Transposase protein Herpes_UL6 PF01763.11 EKG10058.1 - 0.88 7.6 5.9 1.4 6.9 4.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like FlxA PF14282.1 EKG10058.1 - 1.1 9.1 10.7 0.096 12.6 3.5 2.1 2 0 0 2 2 2 0 FlxA-like protein VSG_B PF13206.1 EKG10058.1 - 1.4 7.9 12.8 0.056 12.5 2.2 2.1 2 0 0 2 2 2 0 Trypanosomal VSG domain SpoVR PF04293.8 EKG10058.1 - 2.4 6.4 6.8 4.1 5.6 4.7 1.3 1 0 0 1 1 1 0 SpoVR like protein V_ATPase_I PF01496.14 EKG10058.1 - 3.2 5.4 6.1 5 4.8 4.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1192 PF06698.6 EKG10058.1 - 5 7.0 23.4 1.2 8.9 4.4 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Mnd1 PF03962.10 EKG10058.1 - 5.3 6.6 16.7 0.44 10.1 8.0 1.8 2 0 0 2 2 2 0 Mnd1 family DUF812 PF05667.6 EKG10058.1 - 7.2 4.9 16.1 0.27 9.6 5.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Grp1_Fun34_YaaH PF01184.14 EKG10059.1 - 1.4e-30 106.2 19.3 1.9e-30 105.7 13.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3671 PF12420.3 EKG10059.1 - 0.054 13.4 0.2 8.7 6.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function MscS_porin PF12795.2 EKG10060.1 - 0.0002 20.7 7.9 0.0002 20.7 5.4 2.1 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Transcrip_act PF04949.8 EKG10060.1 - 0.00054 19.6 8.3 0.1 12.2 0.0 2.5 2 0 0 2 2 2 2 Transcriptional activator Filament PF00038.16 EKG10060.1 - 0.0014 18.1 5.8 0.0014 18.1 4.0 3.1 2 1 1 4 4 4 1 Intermediate filament protein AAA_13 PF13166.1 EKG10060.1 - 0.005 15.3 9.3 0.0072 14.8 6.4 1.2 1 0 0 1 1 1 1 AAA domain CENP-F_leu_zip PF10473.4 EKG10060.1 - 0.0099 15.7 23.5 0.95 9.3 8.0 3.3 2 1 1 3 3 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FimP PF09766.4 EKG10060.1 - 0.015 14.4 0.2 0.015 14.4 0.2 2.3 1 1 0 2 2 2 0 Fms-interacting protein Reo_sigmaC PF04582.7 EKG10060.1 - 0.016 14.3 4.7 0.42 9.7 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CorA PF01544.13 EKG10060.1 - 0.016 14.2 6.3 0.22 10.5 0.0 2.5 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 EKG10060.1 - 0.049 13.7 7.4 0.14 12.2 0.1 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EKG10060.1 - 0.093 11.9 16.4 1.3 8.2 0.3 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EKG10060.1 - 0.16 11.7 17.9 0.56 9.9 1.5 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EKG10060.1 - 0.17 10.5 16.9 0.46 9.0 5.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4164 PF13747.1 EKG10060.1 - 0.19 11.9 23.7 1 9.5 4.6 3.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Gp58 PF07902.6 EKG10060.1 - 0.22 9.7 2.9 0.86 7.7 0.0 2.0 1 1 1 2 2 2 0 gp58-like protein Spectrin PF00435.16 EKG10060.1 - 0.24 11.7 23.0 0.37 11.0 3.2 4.6 2 1 2 4 4 4 0 Spectrin repeat DUF904 PF06005.7 EKG10060.1 - 0.27 11.5 16.1 24 5.2 8.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF904) HSBP1 PF06825.7 EKG10060.1 - 0.32 10.6 2.6 1.6 8.3 0.2 2.6 2 0 0 2 2 2 0 Heat shock factor binding protein 1 IncA PF04156.9 EKG10060.1 - 0.44 10.1 30.1 0.06 12.9 10.1 2.9 2 1 1 3 3 3 0 IncA protein SlyX PF04102.7 EKG10060.1 - 0.45 10.9 14.7 0.47 10.8 0.0 4.5 2 1 2 4 4 4 0 SlyX OmpH PF03938.9 EKG10060.1 - 0.64 9.9 13.9 18 5.2 9.6 2.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EKG10060.1 - 0.83 8.6 18.4 0.55 9.2 7.0 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 EKG10060.1 - 1.8 8.4 20.3 0.48 10.3 7.0 3.4 2 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding XhlA PF10779.4 EKG10060.1 - 1.9 8.4 12.7 6.7 6.7 0.1 3.9 2 1 0 2 2 2 0 Haemolysin XhlA Macoilin PF09726.4 EKG10060.1 - 2.1 6.5 14.3 3.1 5.9 9.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Tho2 PF11262.3 EKG10060.1 - 2.8 6.9 6.5 1.3 7.9 2.7 1.7 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4200 PF13863.1 EKG10060.1 - 2.8 7.8 23.4 0.41 10.5 2.7 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Tup_N PF08581.5 EKG10060.1 - 3.7 7.7 10.4 1.4 9.1 1.0 3.1 3 1 0 3 3 2 0 Tup N-terminal ATG16 PF08614.6 EKG10060.1 - 3.8 7.2 25.1 1.2 8.9 7.8 3.1 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.3 EKG10060.1 - 3.9 6.6 12.6 5.7 6.1 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GrpE PF01025.14 EKG10060.1 - 5.2 6.5 18.6 3.6 7.1 2.1 2.7 1 1 0 2 2 2 0 GrpE DUF1515 PF07439.6 EKG10060.1 - 5.5 6.8 7.6 5.1 6.9 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Herpes_UL6 PF01763.11 EKG10060.1 - 6.5 4.8 11.9 1.9 6.5 4.7 2.1 1 1 2 3 3 3 0 Herpesvirus UL6 like Atg14 PF10186.4 EKG10060.1 - 6.7 5.5 20.8 2.7 6.8 9.6 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TMF_TATA_bd PF12325.3 EKG10060.1 - 7.4 6.3 19.7 17 5.1 0.2 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding SMC_N PF02463.14 EKG10061.1 - 8.2e-71 237.7 0.2 3.6e-70 235.6 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKG10061.1 - 9.4e-23 80.4 0.4 6.6e-22 77.7 0.1 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EKG10061.1 - 2.4e-11 44.3 16.8 2.4e-11 44.3 11.7 6.9 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EKG10061.1 - 2.3e-10 40.9 11.8 3.7e-05 23.8 0.0 3.5 4 1 0 4 4 4 2 AAA domain Reo_sigmaC PF04582.7 EKG10061.1 - 2.7e-05 23.5 31.0 0.43 9.7 2.9 7.0 3 2 4 7 7 7 5 Reovirus sigma C capsid protein AAA_29 PF13555.1 EKG10061.1 - 0.00079 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.3 EKG10061.1 - 0.0055 16.4 10.5 0.0055 16.4 7.3 11.9 5 2 8 13 13 13 1 TATA element modulatory factor 1 DNA binding Dak2 PF02734.12 EKG10062.1 - 4.6e-15 55.7 0.9 2.5e-14 53.3 0.2 2.2 2 0 0 2 2 2 1 DAK2 domain ECH PF00378.15 EKG10063.1 - 5.2e-53 179.6 0.0 6.6e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SGL PF08450.7 EKG10064.1 - 2.4e-08 33.6 0.0 2.7e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Methyltransf_16 PF10294.4 EKG10065.1 - 5.1e-13 48.8 0.0 3.3e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EKG10065.1 - 0.074 13.6 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EKG10066.1 - 8.6e-82 274.7 0.0 1.3e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG10066.1 - 0.021 15.7 0.0 0.055 14.4 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain BNIP3 PF06553.7 EKG10067.1 - 0.17 11.2 0.8 0.18 11.1 0.5 1.0 1 0 0 1 1 1 0 BNIP3 bZIP_1 PF00170.16 EKG10068.1 - 1.5e-08 34.4 7.8 2.6e-08 33.6 5.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG10068.1 - 0.00079 19.1 6.4 0.0016 18.2 4.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Spt5_N PF11942.3 EKG10068.1 - 0.011 16.3 5.9 0.24 12.0 0.1 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal TIR_2 PF13676.1 EKG10068.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 TIR domain bZIP_Maf PF03131.12 EKG10068.1 - 0.022 15.0 7.4 0.022 15.0 5.1 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Adeno_PIX PF03955.9 EKG10068.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF349 PF03993.7 EKG10068.1 - 0.37 10.9 4.6 0.79 9.9 3.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF3484 PF11983.3 EKG10068.1 - 3.2 8.6 12.2 30 5.5 8.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Fe-ADH PF00465.14 EKG10069.1 - 3e-64 216.9 0.0 3.9e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKG10069.1 - 6.9e-15 55.0 0.0 9.3e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase TIM PF00121.13 EKG10070.1 - 5.6e-55 186.0 0.0 6.4e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase HBS1_N PF08938.5 EKG10070.1 - 0.079 13.0 0.0 0.38 10.9 0.0 2.0 2 0 0 2 2 2 0 HBS1 N-terminus MTHFR PF02219.12 EKG10071.1 - 7.2e-99 330.4 0.0 9.4e-99 330.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PAN_3 PF08277.7 EKG10073.1 - 0.021 14.4 0.2 0.053 13.1 0.1 1.6 2 0 0 2 2 2 0 PAN-like domain adh_short PF00106.20 EKG10075.1 - 3.6e-11 43.2 0.0 6.4e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Erg28 PF03694.8 EKG10076.1 - 1.6e-36 124.6 0.0 1.9e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Erg28 like protein TraV PF09676.5 EKG10077.1 - 5.3 7.7 8.5 6.2 7.5 5.9 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) PAS_3 PF08447.6 EKG10078.1 - 1.5e-09 37.8 0.0 4.1e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EKG10078.1 - 7.8e-09 35.8 0.0 4.2e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EKG10078.1 - 4.9e-06 26.4 0.0 0.00045 20.1 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EKG10078.1 - 1.5e-05 24.7 0.0 0.0044 16.7 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EKG10078.1 - 4e-05 23.5 0.0 0.041 13.9 0.0 2.9 3 0 0 3 3 3 2 PAS fold WD40 PF00400.27 EKG10079.1 - 7.7e-18 63.6 9.5 1.2e-08 34.4 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3357 PF11837.3 EKG10080.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ArfGap PF01412.13 EKG10081.1 - 9.3e-35 118.9 0.2 2.1e-34 117.7 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf MAPEG PF01124.13 EKG10082.1 - 2.8e-15 56.0 0.6 3.7e-15 55.6 0.4 1.1 1 0 0 1 1 1 1 MAPEG family HD_3 PF13023.1 EKG10083.1 - 2.5e-47 160.7 0.0 3.1e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 HD domain HAUS6_N PF14661.1 EKG10084.1 - 8.8e-49 166.0 0.3 8.8e-49 166.0 0.2 1.9 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_L15e PF00827.12 EKG10086.1 - 7.3e-91 302.8 13.3 8.3e-91 302.7 9.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 Pkinase PF00069.20 EKG10088.1 - 3.1e-67 226.4 0.0 4.1e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG10088.1 - 5.9e-34 117.3 0.0 1.4e-33 116.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG10088.1 - 2.3e-06 26.8 0.0 6.8e-06 25.2 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EKG10088.1 - 0.00046 19.3 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG10088.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKG10088.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 EKG10088.1 - 0.26 10.0 0.1 3.3 6.3 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase DnaJ PF00226.26 EKG10091.1 - 1.3e-20 72.8 0.1 2.5e-20 71.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain PSP1 PF04468.7 EKG10092.1 - 9e-27 92.8 0.6 1.9e-26 91.8 0.4 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region MARVEL PF01284.18 EKG10094.1 - 2.5e-29 101.9 11.3 3.2e-29 101.6 7.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain HlyIII PF03006.15 EKG10094.1 - 0.42 10.0 5.7 0.8 9.0 3.2 1.7 2 0 0 2 2 2 0 Haemolysin-III related DUF4131 PF13567.1 EKG10094.1 - 7.6 5.8 7.9 56 3.0 5.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Fig1 PF12351.3 EKG10094.1 - 9.7 6.0 7.9 13 5.5 5.0 1.6 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 HAD PF12710.2 EKG10095.1 - 8.4e-17 61.9 0.0 1.2e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG10095.1 - 8.4e-14 52.4 0.1 6.2e-13 49.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG10095.1 - 5.8e-09 35.8 0.0 7.1e-08 32.3 0.0 2.4 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EKG10095.1 - 4e-06 27.1 0.0 1.4e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EKG10095.1 - 0.00013 21.2 0.0 0.063 12.4 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Acid_PPase PF12689.2 EKG10095.1 - 0.047 13.3 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 Acid Phosphatase DUF705 PF05152.7 EKG10095.1 - 0.052 12.5 0.1 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) adh_short PF00106.20 EKG10096.1 - 3.3e-18 66.1 0.1 5e-17 62.3 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10096.1 - 1.5e-06 27.9 0.0 8.5e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EKG10096.1 - 1.5e-05 24.9 0.0 5.9e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG10096.1 - 0.00034 20.1 0.0 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Glyco_transf_28 PF03033.15 EKG10097.1 - 7.6e-19 67.8 0.0 2.3e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EKG10097.1 - 3.9e-07 28.9 0.0 6.7e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EKG10097.1 - 9.6e-05 22.0 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Ank_2 PF12796.2 EKG10098.1 - 3.7e-55 184.2 0.0 6.5e-17 61.6 0.0 7.6 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG10098.1 - 9.9e-44 146.3 6.1 3.1e-09 36.7 0.0 10.3 4 3 6 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.25 EKG10098.1 - 1.5e-43 144.5 7.7 1.1e-05 25.0 0.0 12.3 11 1 1 12 12 12 7 Ankyrin repeat Ank_4 PF13637.1 EKG10098.1 - 3.1e-42 142.2 3.4 1.9e-11 44.1 0.0 8.9 6 3 4 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG10098.1 - 1.1e-28 96.3 0.3 0.002 18.1 0.0 11.1 11 0 0 11 11 11 5 Ankyrin repeat NACHT PF05729.7 EKG10098.1 - 5.9e-08 32.5 0.1 1.3e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EKG10098.1 - 2e-05 24.6 0.0 7.7e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG10098.1 - 0.0021 18.2 0.0 0.014 15.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain PGAP1 PF07819.8 EKG10098.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein KAP_NTPase PF07693.9 EKG10098.1 - 0.2 10.6 0.1 0.42 9.5 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain DEAD PF00270.24 EKG10099.1 - 4e-26 91.5 0.0 1.1e-25 90.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EKG10099.1 - 1.4e-11 44.7 2.6 2.7e-10 40.6 1.7 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EKG10099.1 - 1.8e-11 43.7 0.1 5.3e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EKG10099.1 - 0.00079 19.3 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ORC4_C PF14629.1 EKG10100.1 - 2.7e-51 173.8 0.0 4.6e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EKG10100.1 - 1.4e-18 67.5 4.4 2.2e-18 66.8 0.2 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EKG10100.1 - 1.5e-07 31.6 0.1 4.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKG10100.1 - 2.6e-07 30.9 0.0 6.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKG10100.1 - 3e-07 30.3 0.1 6e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EKG10100.1 - 1.2e-06 28.3 0.3 5.1e-06 26.2 0.2 2.1 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.8 EKG10100.1 - 1.2e-05 24.4 0.1 1.9e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EKG10100.1 - 5.5e-05 22.2 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 EKG10100.1 - 0.00038 20.3 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EKG10100.1 - 0.0015 17.4 0.1 0.0045 15.8 0.1 1.7 2 0 0 2 2 2 1 NB-ARC domain ATP-synt_ab PF00006.20 EKG10100.1 - 0.0024 17.4 0.0 0.0049 16.3 0.0 1.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EKG10100.1 - 0.0055 15.6 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 EKG10100.1 - 0.0057 16.1 0.0 0.69 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain DUF2791 PF10923.3 EKG10100.1 - 0.006 15.2 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) AAA_17 PF13207.1 EKG10100.1 - 0.0094 16.7 0.0 0.022 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EKG10100.1 - 0.01 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EKG10100.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EKG10100.1 - 0.022 14.2 0.0 0.058 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 EKG10100.1 - 0.027 13.4 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EKG10100.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EKG10100.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 EKG10100.1 - 0.042 13.5 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 EKG10100.1 - 0.056 12.0 0.1 0.13 10.8 0.1 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.9 EKG10100.1 - 0.076 11.9 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase TIP49 PF06068.8 EKG10100.1 - 0.081 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activat PF00158.21 EKG10100.1 - 0.13 11.6 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain p450 PF00067.17 EKG10101.1 - 7.9e-66 222.4 0.0 1e-65 222.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 EKG10103.1 - 9.9e-22 77.2 0.0 3.8e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10103.1 - 2.5e-14 53.7 0.0 3.6e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10103.1 - 4.5e-14 52.3 0.0 2e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG10103.1 - 9.7e-14 51.5 0.0 8.3e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG10103.1 - 4.8e-13 49.4 0.0 1.3e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG10103.1 - 9.7e-13 48.1 0.0 2.1e-12 47.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG10103.1 - 1e-08 34.5 0.0 1.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EKG10103.1 - 7e-08 32.5 0.0 1.9e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG10103.1 - 0.00089 18.3 0.0 0.074 12.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EKG10103.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain EF-hand_7 PF13499.1 EKG10104.1 - 5.4e-14 52.0 0.1 8.5e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EKG10104.1 - 3e-11 42.1 0.4 0.00015 21.3 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EKG10104.1 - 2.8e-09 35.6 0.4 0.0025 17.0 0.0 3.7 4 1 1 5 5 5 2 EF hand EF-hand_9 PF14658.1 EKG10104.1 - 7.7e-08 32.1 0.0 0.0003 20.6 0.0 2.7 1 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EKG10104.1 - 0.052 12.9 0.7 3.6 7.1 0.1 2.7 2 0 0 2 2 2 0 EF hand ACBP PF00887.14 EKG10105.1 - 1.4e-21 75.9 1.3 1.5e-21 75.8 0.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein RPE65 PF03055.10 EKG10107.1 - 1.2e-107 360.4 0.0 2.3e-107 359.5 0.0 1.4 1 1 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.13 EKG10108.1 - 0.0015 17.4 0.0 0.0032 16.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rad51 PF08423.6 EKG10110.1 - 0.017 14.0 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad51 AAA_25 PF13481.1 EKG10110.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EKG10110.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MOSC PF03473.12 EKG10111.1 - 4.2e-18 65.0 0.0 1e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EKG10111.1 - 1.5e-10 40.7 0.0 3.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain LEA_3 PF03242.8 EKG10111.1 - 0.033 14.4 0.1 0.07 13.3 0.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein HIT PF01230.18 EKG10112.1 - 7.5e-24 84.1 0.8 1.4e-23 83.2 0.1 1.7 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EKG10112.1 - 1.4e-06 28.5 0.0 2.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Dak1 PF02733.12 EKG10113.1 - 7.7e-78 261.3 0.0 1.1e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Xan_ur_permease PF00860.15 EKG10113.1 - 3.1e-69 233.3 32.3 2.6e-68 230.2 22.4 2.1 1 1 0 1 1 1 1 Permease family FA_desaturase PF00487.19 EKG10114.1 - 4.5e-18 65.6 13.7 4.5e-18 65.6 9.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EKG10114.1 - 8.7e-17 60.6 0.1 1.9e-16 59.6 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA PF00004.24 EKG10115.1 - 3.1e-09 37.1 0.0 7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prp19_bind PF06991.6 EKG10116.1 - 0.058 12.6 0.1 0.068 12.4 0.1 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF4041 PF13250.1 EKG10116.1 - 0.081 12.5 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) MMR_HSR1_C PF08438.5 EKG10116.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal IGF2_C PF08365.6 EKG10116.1 - 0.12 12.1 0.4 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 Insulin-like growth factor II E-peptide GDPD PF03009.12 EKG10118.1 - 4.7e-12 45.9 0.0 1.4e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family HET PF06985.6 EKG10120.1 - 1.1e-11 45.0 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FTA2 PF13095.1 EKG10122.1 - 3.1e-23 82.4 0.0 4.2e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Resolvase PF00239.16 EKG10122.1 - 0.011 15.5 0.1 0.023 14.5 0.1 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain PCP PF02429.10 EKG10123.1 - 0.56 10.3 5.2 1.8 8.6 0.7 2.7 1 1 1 2 2 2 0 Peridinin-chlorophyll A binding protein Peptidase_M3 PF01432.15 EKG10124.1 - 6.8e-139 463.8 0.0 1e-138 463.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 PHP PF02811.14 EKG10124.1 - 0.0025 17.6 0.6 0.24 11.1 0.0 2.8 3 0 0 3 3 3 2 PHP domain Fungal_trans PF04082.13 EKG10126.1 - 7.5e-06 24.9 0.3 2.9e-05 23.0 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG10126.1 - 6.9e-05 22.6 7.9 0.00012 21.9 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin PF02996.12 EKG10126.1 - 0.085 12.5 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Prefoldin subunit NOT2_3_5 PF04153.13 EKG10127.1 - 6.9e-30 103.6 1.1 6.9e-30 103.6 0.8 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family PAT1 PF09770.4 EKG10127.1 - 4.3 5.4 16.8 6.2 4.9 11.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MRP-L47 PF06984.8 EKG10128.1 - 3.4e-24 84.5 1.6 6.7e-24 83.6 1.1 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 EKG10129.1 - 1.3e-182 607.0 0.0 1.5e-182 606.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EKG10129.1 - 0.13 12.3 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain SRPRB PF09439.5 EKG10130.1 - 4.9e-26 91.0 0.0 1.5e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKG10130.1 - 2.1e-06 27.6 0.0 3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EKG10130.1 - 1.2e-05 24.6 0.0 0.0086 15.3 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EKG10130.1 - 0.0015 17.9 0.0 0.0038 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EKG10130.1 - 0.0022 17.1 0.1 0.0052 15.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG10130.1 - 0.004 17.1 3.1 0.036 14.0 2.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG10130.1 - 0.0042 17.2 0.0 0.0064 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 EKG10130.1 - 0.0082 15.6 0.0 0.11 11.9 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.24 EKG10130.1 - 0.0089 16.2 0.1 0.071 13.3 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EKG10130.1 - 0.012 15.1 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.1 EKG10130.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG10130.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EKG10130.1 - 0.015 14.4 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 EKG10130.1 - 0.02 15.2 0.3 0.031 14.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EKG10130.1 - 0.033 14.6 0.0 0.09 13.2 0.0 1.8 2 1 0 2 2 2 0 Miro-like protein IstB_IS21 PF01695.12 EKG10130.1 - 0.035 13.5 1.1 0.13 11.6 0.2 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 EKG10130.1 - 0.054 13.3 0.1 0.088 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EKG10130.1 - 0.058 12.8 0.1 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EKG10130.1 - 0.065 12.7 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EKG10130.1 - 0.079 12.9 0.2 0.12 12.3 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EKG10130.1 - 0.09 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKG10130.1 - 0.12 13.1 0.1 0.25 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 EKG10131.1 - 2.9e-19 69.6 0.1 4.8e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10131.1 - 9.3e-11 41.7 0.1 1.6e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG10131.1 - 1.5e-07 31.4 0.1 2.3e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG10131.1 - 9.5e-06 25.2 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG10131.1 - 3.7e-05 22.7 0.0 7.3e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein YjeF_N PF03853.10 EKG10131.1 - 0.02 14.5 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus NAD_binding_10 PF13460.1 EKG10131.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EKG10131.1 - 0.084 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family EAP30 PF04157.11 EKG10133.1 - 2e-45 154.6 0.0 2.2e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PorB PF11565.3 EKG10133.1 - 0.14 12.3 0.6 0.23 11.6 0.4 1.3 1 0 0 1 1 1 0 Alpha helical Porin B SAC3_GANP PF03399.11 EKG10135.1 - 2.9e-69 232.7 0.6 4e-69 232.2 0.4 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EKG10135.1 - 0.00013 21.7 0.2 0.00041 20.1 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 EKG10136.1 - 8.6e-26 89.0 0.0 1.5e-11 43.4 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EKG10136.1 - 1.2e-19 69.6 0.2 4e-10 39.1 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EKG10136.1 - 2.9e-13 49.0 0.0 1.1e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EKG10136.1 - 4.2e-13 49.0 0.0 1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EKG10136.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 PB1 domain IBR PF01485.16 EKG10138.1 - 0.00014 21.6 15.5 0.00043 20.1 5.0 4.5 4 1 0 4 4 4 2 IBR domain Peptidase_M28 PF04389.12 EKG10139.1 - 2.2e-28 99.2 0.0 3.4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EKG10139.1 - 8e-05 22.2 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SGL PF08450.7 EKG10140.1 - 0.013 14.8 0.1 6.3 6.0 0.0 3.1 1 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Abhydrolase_6 PF12697.2 EKG10141.1 - 3e-07 30.5 0.0 3.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG10141.1 - 3.9e-07 29.9 0.0 9.2e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EKG10143.1 - 8e-55 186.1 0.0 5e-43 147.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 FAD_binding_4 PF01565.18 EKG10147.1 - 3.3e-13 49.3 0.0 6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_transf_90 PF05686.7 EKG10149.1 - 6.7e-27 94.1 0.8 9.3e-27 93.7 0.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EKG10149.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_hydro_12 PF01670.11 EKG10151.1 - 2.8e-34 118.1 0.5 4.7e-34 117.4 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF2418 PF10332.4 EKG10152.1 - 7.6e-35 119.1 0.2 1.2e-34 118.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 EKG10153.1 - 8.3e-05 22.8 0.0 9.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF3704 PF12488.3 EKG10153.1 - 0.021 14.4 0.1 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) FAD_binding_3 PF01494.14 EKG10154.1 - 4.2e-29 101.7 0.4 1.5e-28 99.8 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain E1_DerP2_DerF2 PF02221.10 EKG10154.1 - 3.5e-15 56.4 0.0 6.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 ML domain DAO PF01266.19 EKG10154.1 - 4.4e-14 52.1 3.1 2.3e-06 26.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG10154.1 - 8.1e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG10154.1 - 2.9e-07 29.7 1.2 4.2e-07 29.1 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EKG10154.1 - 5.2e-07 28.4 0.4 2e-06 26.5 0.2 1.8 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EKG10154.1 - 9.4e-06 24.9 0.2 1.5e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG10154.1 - 1.9e-05 24.5 1.0 6.4e-05 22.8 0.7 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG10154.1 - 4.6e-05 23.7 0.2 0.019 15.3 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG10154.1 - 0.00016 21.8 0.0 0.00037 20.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EKG10154.1 - 0.00018 20.7 0.4 0.0026 16.9 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EKG10154.1 - 0.0007 18.5 0.5 0.0012 17.8 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EKG10154.1 - 0.00071 18.5 0.4 0.0024 16.8 0.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.5 EKG10154.1 - 0.0036 16.1 0.0 0.0082 14.9 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.12 EKG10154.1 - 0.0059 15.7 0.2 0.0099 14.9 0.2 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EKG10154.1 - 0.037 12.6 1.1 0.15 10.6 0.2 1.9 1 1 1 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EKG10154.1 - 0.096 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EKG10155.1 - 1.6e-14 53.4 0.0 3e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.16 EKG10155.1 - 0.32 10.9 2.6 0.59 10.1 1.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor Herpes_UL32 PF06070.6 EKG10155.1 - 2.3 6.5 6.1 2.9 6.2 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Abhydrolase_3 PF07859.8 EKG10156.1 - 1.8e-17 63.6 0.0 6.9e-13 48.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG10156.1 - 9.7e-11 41.2 0.0 1.2e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG10156.1 - 5.2e-09 36.0 0.0 1.1e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG10156.1 - 2.2e-08 33.8 0.0 0.0051 16.2 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.23 EKG10156.1 - 2.5e-08 33.1 0.8 4e-07 29.1 0.6 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EKG10156.1 - 4.5e-07 29.9 0.2 7.1e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EKG10156.1 - 0.0015 17.0 0.0 0.007 14.8 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 EKG10156.1 - 0.014 14.6 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EKG10156.1 - 0.02 14.3 0.0 0.71 9.2 0.0 2.7 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 EKG10156.1 - 0.087 12.0 0.7 11 5.1 0.1 2.5 3 0 0 3 3 3 0 Esterase PHB depolymerase Cupin_6 PF12852.2 EKG10157.1 - 0.00022 20.9 0.1 0.00036 20.1 0.1 1.4 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EKG10157.1 - 0.0092 15.4 0.9 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EKG10157.1 - 0.069 12.5 0.2 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) HeLo PF14479.1 EKG10158.1 - 4.1e-24 85.5 3.0 4.1e-24 85.5 2.1 1.7 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.20 EKG10158.1 - 1.9e-06 27.2 0.0 6.2e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase PF00069.20 EKG10159.1 - 8.2e-39 133.3 0.0 1.5e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG10159.1 - 9.4e-31 106.8 0.0 1.8e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EKG10159.1 - 7.4e-27 93.5 1.1 2.4e-08 34.1 0.0 3.8 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG10159.1 - 1.9e-21 74.7 6.2 2.1e-06 27.2 0.1 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EKG10159.1 - 3.8e-21 75.0 3.6 6.7e-06 26.4 0.1 5.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG10159.1 - 3.1e-16 59.0 9.5 0.00015 21.8 0.0 5.4 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG10159.1 - 7e-13 47.4 1.7 0.023 14.9 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Kinase-like PF14531.1 EKG10159.1 - 0.0011 18.0 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG10159.1 - 0.0019 17.2 0.0 0.0048 15.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family INT_SG_DDX_CT_C PF15300.1 EKG10160.1 - 0.098 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Myb_DNA-binding PF00249.26 EKG10161.1 - 2.2e-29 101.2 3.6 4.9e-11 42.5 0.4 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG10161.1 - 1.3e-27 95.6 0.6 4e-13 49.2 0.2 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EKG10161.1 - 0.001 19.2 5.0 0.11 12.7 0.2 3.4 3 1 0 4 4 4 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 EKG10161.1 - 0.33 10.8 5.5 80 3.2 3.8 3.0 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 EKG10161.1 - 0.33 11.0 9.7 2.3 8.3 1.9 3.2 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain AAA_16 PF13191.1 EKG10162.1 - 2.6e-05 24.3 0.7 0.0011 19.0 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG10162.1 - 0.00014 22.0 0.3 0.00039 20.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKG10162.1 - 0.00072 19.3 0.0 0.0018 18.0 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase KaiC PF06745.8 EKG10162.1 - 0.0029 16.7 0.3 0.006 15.7 0.2 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 EKG10162.1 - 0.021 14.2 0.8 0.16 11.3 0.1 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EKG10162.1 - 0.047 13.8 0.3 0.15 12.2 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EKG10162.1 - 0.054 12.9 0.4 4 6.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EKG10162.1 - 0.067 12.6 0.0 0.2 11.1 0.0 1.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain A_deaminase PF00962.17 EKG10162.1 - 0.069 12.0 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase AAA_24 PF13479.1 EKG10162.1 - 0.31 10.5 1.8 4.2 6.8 0.2 2.5 2 0 0 2 2 2 0 AAA domain HemY_N PF07219.8 EKG10163.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus PA14_2 PF10528.4 EKG10164.1 - 3e-20 72.2 0.1 8.5e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 GLEYA domain Glyco_hydro_39 PF01229.12 EKG10165.1 - 3.3e-32 111.5 0.0 2e-31 108.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 39 Cellulase-like PF12876.2 EKG10165.1 - 0.052 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like PhyH PF05721.8 EKG10166.1 - 2.8e-21 76.5 0.1 3.9e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 EKG10167.1 - 6.3e-23 81.0 0.2 7.3e-23 80.7 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mac PF12464.3 EKG10168.1 - 8.7e-20 70.4 0.0 2e-19 69.3 0.0 1.6 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EKG10168.1 - 9.6e-14 50.6 4.2 9.6e-14 50.6 2.9 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EKG10168.1 - 2.3e-13 48.9 11.6 7.4e-13 47.3 3.9 2.6 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) rve_3 PF13683.1 EKG10168.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain CBM_4_9 PF02018.12 EKG10169.1 - 0.03 14.3 0.1 0.087 12.8 0.1 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain PAN_4 PF14295.1 EKG10169.1 - 0.11 12.2 4.3 0.85 9.3 0.0 3.1 2 1 0 2 2 2 0 PAN domain R3H-assoc PF13902.1 EKG10170.1 - 2.1e-19 69.7 9.7 4.8e-19 68.6 6.7 1.6 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EKG10170.1 - 0.0024 17.5 2.1 0.0091 15.6 0.0 2.6 3 0 0 3 3 3 1 R3H domain D5_N PF08706.6 EKG10170.1 - 0.15 12.1 2.4 0.3 11.1 1.7 1.5 1 0 0 1 1 1 0 D5 N terminal like NAD_binding_2 PF03446.10 EKG10171.1 - 4.2e-31 107.9 0.1 6.2e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EKG10171.1 - 1e-10 41.9 0.0 3.4e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EKG10171.1 - 4.7e-08 33.2 0.0 8.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 EKG10171.1 - 1.6e-07 31.3 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase TrkA_N PF02254.13 EKG10171.1 - 0.0042 17.0 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EKG10171.1 - 0.029 13.3 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EKG10171.1 - 0.084 12.2 0.1 0.81 9.0 0.0 2.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF619 PF04768.8 EKG10172.1 - 1.3e-51 174.4 0.0 2.7e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Glyco_hydro_43 PF04616.9 EKG10174.1 - 0.0012 17.9 2.4 0.0012 17.9 1.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Pro-kuma_activ PF09286.6 EKG10175.1 - 4.5e-51 172.6 0.2 1.2e-50 171.2 0.1 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EKG10175.1 - 1.1e-05 24.7 0.3 1.7e-05 24.0 0.2 1.2 1 0 0 1 1 1 1 Subtilase family DUF3176 PF11374.3 EKG10176.1 - 3.8e-31 107.2 1.0 1.1e-30 105.7 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) PD40 PF07676.7 EKG10177.1 - 8.1e-52 172.1 18.4 3.2e-09 36.2 0.2 9.6 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EKG10177.1 - 3e-17 62.2 4.0 0.00019 20.1 0.3 7.0 5 1 1 6 6 6 6 Dipeptidyl peptidase IV (DPP IV) N-terminal region SGL PF08450.7 EKG10177.1 - 0.00018 20.9 6.4 0.013 14.9 0.2 4.3 3 2 3 6 6 6 2 SMP-30/Gluconolaconase/LRE-like region DUF1513 PF07433.6 EKG10177.1 - 0.0035 16.2 0.3 0.54 9.1 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1513) Pectate_lyase22 PF14583.1 EKG10177.1 - 0.011 14.2 0.6 2.9 6.2 0.0 3.9 4 1 1 5 5 5 0 Oligogalacturonate lyase Bac_rhamnosid_N PF08531.5 EKG10177.1 - 0.022 14.2 0.0 0.059 12.8 0.0 1.7 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain WD40 PF00400.27 EKG10177.1 - 0.22 11.4 6.5 47 4.0 0.2 6.0 6 1 0 6 6 6 0 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EKG10177.1 - 7.5 5.9 12.5 33 3.9 0.1 6.4 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature FAD_binding_4 PF01565.18 EKG10178.1 - 7.3e-11 41.6 0.0 1.7e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EKG10178.1 - 5.1e-05 23.0 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like ERbeta_N PF12497.3 EKG10178.1 - 0.083 12.7 0.1 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Estrogen receptor beta DUF221 PF02714.10 EKG10182.1 - 1.9e-101 339.1 16.8 2.8e-101 338.6 11.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EKG10182.1 - 8.7e-25 87.0 5.1 5.5e-20 71.5 0.5 2.8 1 1 1 2 2 2 2 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EKG10182.1 - 2.5e-08 33.6 0.6 1.9e-07 30.8 0.0 2.5 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 EKG10182.1 - 7.5e-07 29.5 0.3 2.4e-06 27.9 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4463) RRM_1 PF00076.17 EKG10182.1 - 0.00077 19.0 0.0 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EKG10182.1 - 6.2 4.7 7.5 9.8 4.0 5.2 1.3 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_3 PF01494.14 EKG10183.1 - 3.2e-18 65.9 0.1 2.2e-17 63.1 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG10183.1 - 5.1e-07 29.6 0.7 1.2e-06 28.4 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG10183.1 - 0.00015 21.7 0.0 0.001 18.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG10183.1 - 0.00021 20.2 0.9 0.00037 19.4 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG10183.1 - 0.00026 19.9 4.0 0.012 14.5 0.7 3.4 2 2 2 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG10183.1 - 0.0028 18.0 0.0 0.067 13.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EKG10183.1 - 0.0033 17.2 0.4 0.013 15.2 0.2 2.1 2 0 0 2 2 2 1 ThiF family SE PF08491.5 EKG10183.1 - 0.019 13.8 0.0 0.047 12.5 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.17 EKG10183.1 - 0.066 12.0 0.4 0.12 11.2 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EKG10183.1 - 0.1 12.3 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EKG10183.1 - 0.12 10.9 0.2 0.3 9.6 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase DUF605 PF04652.11 EKG10184.1 - 0.45 9.8 14.6 0.5 9.6 10.1 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EKG10184.1 - 4.8 6.9 6.5 5.3 6.8 4.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VitD-bind_III PF09164.5 EKG10187.1 - 0.1 12.2 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Vitamin D binding protein, domain III AMP-binding PF00501.23 EKG10188.1 - 4.2e-69 232.9 0.0 5.6e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG10188.1 - 1e-14 55.2 0.1 2.3e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF605 PF04652.11 EKG10188.1 - 0.13 11.6 1.2 0.19 11.1 0.8 1.2 1 0 0 1 1 1 0 Vta1 like Cellulase PF00150.13 EKG10191.1 - 2.6e-05 23.5 0.0 0.00011 21.4 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_4 PF01565.18 EKG10192.1 - 3.9e-26 91.1 2.6 6.6e-26 90.4 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG10192.1 - 1.2e-12 47.4 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like PEP_mutase PF13714.1 EKG10194.1 - 3.6e-37 127.8 1.0 4.6e-37 127.5 0.7 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EKG10194.1 - 5.4e-21 74.4 1.9 6.5e-21 74.1 1.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family p450 PF00067.17 EKG10196.1 - 3.1e-40 138.1 0.0 3.7e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BBP1_C PF15272.1 EKG10199.1 - 0.043 13.3 0.6 0.061 12.8 0.4 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal MARVEL PF01284.18 EKG10201.1 - 2.4e-07 30.6 12.7 3.9e-07 29.9 8.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain SKG6 PF08693.5 EKG10201.1 - 0.12 11.7 0.8 0.28 10.5 0.5 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3593 PF12159.3 EKG10201.1 - 1.2 8.9 7.0 8 6.3 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3593) TPR_11 PF13414.1 EKG10202.1 - 3.7e-14 52.0 2.8 6.6e-10 38.4 0.3 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EKG10202.1 - 5.9e-10 38.2 8.4 0.00067 19.3 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKG10202.1 - 1.1e-06 27.9 0.4 0.66 9.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKG10202.1 - 3.8e-06 26.2 5.9 0.032 13.8 0.2 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EKG10202.1 - 6.4e-06 26.0 2.8 0.0025 17.7 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG10202.1 - 6e-05 23.6 8.9 0.0018 18.8 2.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG10202.1 - 0.00052 20.3 6.0 0.0021 18.3 0.2 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EKG10202.1 - 0.0064 16.6 0.2 0.019 15.0 0.1 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EKG10202.1 - 0.0087 15.8 5.7 0.25 11.2 2.9 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG10202.1 - 0.02 15.3 5.3 1.2 9.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.5 EKG10202.1 - 0.035 13.1 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_7 PF13176.1 EKG10202.1 - 0.09 12.6 5.7 1.1 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG10202.1 - 0.13 12.9 16.0 0.072 13.7 2.5 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EKG10202.1 - 4.6 7.3 6.0 18 5.4 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MUG113 PF13455.1 EKG10203.1 - 1.4e-29 102.3 0.2 3.5e-29 101.0 0.1 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EKG10203.1 - 1.2e-22 80.1 0.1 4.1e-22 78.4 0.1 1.9 1 0 0 1 1 1 1 T5orf172 domain DUF4635 PF15466.1 EKG10204.1 - 0.013 14.7 0.1 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) DUF3936 PF13072.1 EKG10204.1 - 0.035 13.5 0.1 0.078 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) gag-asp_proteas PF13975.1 EKG10205.1 - 4.5e-07 29.5 0.0 9.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EKG10205.1 - 5.7e-05 22.9 0.0 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EKG10205.1 - 0.00011 22.6 0.0 0.00028 21.3 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease FlaC_arch PF05377.6 EKG10206.1 - 0.25 11.2 0.8 5 7.0 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 EKG10206.1 - 0.47 9.3 5.8 0.91 8.4 4.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Orbi_VP5 PF00901.12 EKG10206.1 - 0.53 8.4 4.4 0.79 7.8 3.1 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Methyltransf_31 PF13847.1 EKG10207.1 - 1.4e-18 66.9 0.0 4.9e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain GFA PF04828.9 EKG10207.1 - 4e-16 58.7 0.7 7.4e-16 57.8 0.5 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_18 PF12847.2 EKG10207.1 - 1.2e-15 58.0 0.0 3.1e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG10207.1 - 1.4e-14 54.0 0.0 2.2e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10207.1 - 3.5e-14 53.0 0.0 1.4e-12 47.8 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG10207.1 - 8.3e-13 47.9 0.0 9.6e-09 34.6 0.0 2.2 1 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EKG10207.1 - 3.4e-12 46.6 0.0 1e-10 41.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG10207.1 - 4.2e-10 39.6 0.7 1.4e-09 37.9 0.5 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKG10207.1 - 2.7e-09 36.8 0.0 3.1e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EKG10207.1 - 7.6e-09 35.8 0.0 1.7e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG10207.1 - 7.9e-05 22.0 0.0 0.00015 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EKG10207.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EKG10207.1 - 0.008 16.1 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase FmrO PF07091.6 EKG10207.1 - 0.012 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_3 PF01596.12 EKG10207.1 - 0.013 14.5 0.0 0.66 8.9 0.0 2.5 2 1 0 2 2 2 0 O-methyltransferase PrmA PF06325.8 EKG10207.1 - 0.024 13.7 0.1 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.1 EKG10207.1 - 0.032 15.0 0.0 0.092 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EKG10207.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain K_channel_TID PF07941.6 EKG10208.1 - 5.1 7.4 13.8 0.29 11.3 2.0 2.4 1 1 1 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HECT PF00632.20 EKG10211.1 - 3e-74 250.0 0.0 4.4e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-LSD1 PF06943.7 EKG10211.1 - 0.4 10.3 3.0 8.2 6.1 3.0 2.2 2 0 0 2 2 2 0 LSD1 zinc finger Amidohydro_5 PF13594.1 EKG10212.1 - 5.6e-06 26.0 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EKG10212.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Endosulfine PF04667.12 EKG10212.1 - 0.12 12.3 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region KRTDAP PF15200.1 EKG10212.1 - 0.16 11.7 0.2 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Keratinocyte differentiation-associated SWIB PF02201.13 EKG10213.1 - 8.8e-15 54.1 0.0 1.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Pyr_redox_3 PF13738.1 EKG10214.1 - 1e-25 90.9 0.0 8.1e-24 84.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG10214.1 - 2.3e-07 29.4 0.0 0.00012 20.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG10214.1 - 3e-06 27.1 0.3 1.7e-05 24.7 0.1 2.3 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG10214.1 - 4.4e-06 26.5 0.1 0.00027 20.7 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EKG10214.1 - 3.1e-05 23.0 0.0 0.0038 16.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EKG10214.1 - 7.7e-05 22.8 0.2 0.017 15.1 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EKG10214.1 - 0.0014 18.5 1.0 6.1 6.6 0.0 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EKG10214.1 - 0.0018 17.4 0.0 0.0052 15.9 0.0 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EKG10214.1 - 0.0028 17.4 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 EKG10214.1 - 0.0035 17.1 0.4 1.7 8.4 0.1 2.6 2 0 0 2 2 2 2 ThiF family Lycopene_cycl PF05834.7 EKG10214.1 - 0.018 13.9 0.0 0.052 12.4 0.0 1.9 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EKG10214.1 - 0.043 14.2 0.2 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EKG10214.1 - 0.077 13.4 0.1 12 6.3 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EKG10214.1 - 0.21 11.5 0.1 3.2 7.7 0.0 2.8 4 0 0 4 4 3 0 TrkA-N domain FAD_binding_3 PF01494.14 EKG10214.1 - 0.23 10.4 1.7 0.42 9.6 0.1 2.2 3 0 0 3 3 3 0 FAD binding domain Tannase PF07519.6 EKG10215.1 - 2.2e-118 395.9 0.0 2.7e-118 395.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EKG10215.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG10215.1 - 0.026 14.4 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family QCR10 PF09796.4 EKG10215.1 - 0.042 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Cys_Met_Meta_PP PF01053.15 EKG10216.1 - 1.9e-137 457.6 0.0 2.3e-137 457.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EKG10216.1 - 4.8e-05 22.5 0.0 0.00018 20.7 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EKG10216.1 - 6.5e-05 21.4 0.0 0.00043 18.6 0.0 1.9 1 1 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.14 EKG10216.1 - 0.00019 20.3 0.1 0.0004 19.2 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 EKG10216.1 - 0.00037 19.3 0.1 0.00054 18.7 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein DUF2415 PF10313.4 EKG10217.1 - 1.8e-15 56.3 0.1 4.7e-15 54.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EKG10217.1 - 0.00084 19.1 0.5 0.25 11.3 0.1 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2630 PF10944.3 EKG10217.1 - 0.25 11.4 4.1 0.21 11.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) HSP70 PF00012.15 EKG10218.1 - 7.8e-269 892.6 14.5 9e-269 892.4 10.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKG10218.1 - 2.4e-14 52.6 4.8 3.7e-12 45.4 1.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EKG10218.1 - 0.00012 21.7 0.0 0.00028 20.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EKG10218.1 - 0.0038 17.0 9.4 2.1 8.1 1.1 4.7 4 1 0 4 4 4 2 Cell division protein FtsA Hydantoinase_A PF01968.13 EKG10218.1 - 0.12 11.4 5.3 1.6 7.7 0.0 3.4 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase COesterase PF00135.23 EKG10221.1 - 1.4e-34 119.7 0.0 1.7e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG10221.1 - 4.3e-05 23.1 0.1 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG10221.1 - 0.13 11.5 0.1 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3982 PF13138.1 EKG10222.1 - 0.038 13.8 0.1 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3982) TPPII_N PF12583.3 EKG10222.1 - 0.16 12.0 3.3 0.24 11.5 2.3 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Dimerisation PF08100.6 EKG10222.1 - 0.27 11.1 1.2 0.35 10.7 0.6 1.5 1 1 0 1 1 1 0 Dimerisation domain amfpi-1 PF12190.3 EKG10222.1 - 0.51 10.8 9.1 1.1 9.7 6.0 1.8 1 1 1 2 2 2 0 Fungal protease inhibitor AAA PF00004.24 EKG10223.1 - 2.2e-42 144.4 2.5 6e-14 52.3 0.0 6.2 6 1 1 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EKG10223.1 - 1.5e-39 135.4 0.0 3.6e-39 134.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG10223.1 - 1.8e-34 119.3 17.3 2.3e-30 105.9 0.1 6.1 5 2 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EKG10223.1 - 1.1e-19 69.9 0.6 1.1e-06 28.2 0.0 5.7 5 0 0 5 5 5 4 Part of AAA domain AAA_22 PF13401.1 EKG10223.1 - 3.1e-15 56.4 4.4 0.031 14.4 0.0 7.4 5 3 0 5 5 5 4 AAA domain AAA_5 PF07728.9 EKG10223.1 - 6.2e-14 51.9 1.7 0.065 12.9 0.0 5.8 5 0 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EKG10223.1 - 8.1e-14 51.6 4.6 0.00056 19.5 0.0 6.0 5 0 0 5 5 5 2 AAA domain AAA_17 PF13207.1 EKG10223.1 - 5.7e-13 49.7 7.1 0.047 14.5 0.0 5.8 5 0 0 5 5 5 4 AAA domain Viral_helicase1 PF01443.13 EKG10223.1 - 8.6e-08 31.9 2.9 0.39 10.1 0.0 6.1 7 0 0 7 7 6 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EKG10223.1 - 1.1e-07 32.2 9.5 0.26 11.5 0.0 5.5 5 0 0 5 5 4 3 AAA domain Mg_chelatase PF01078.16 EKG10223.1 - 1.2e-07 31.1 2.1 0.62 9.1 0.0 5.1 5 1 0 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EKG10223.1 - 1.8e-07 31.2 13.6 0.76 9.7 0.0 6.6 7 0 0 7 7 6 4 AAA ATPase domain RNA_helicase PF00910.17 EKG10223.1 - 2e-07 31.1 0.2 1.6 8.9 0.0 4.7 4 0 0 4 4 4 2 RNA helicase AAA_33 PF13671.1 EKG10223.1 - 3.5e-06 26.9 10.5 1.8 8.4 0.0 6.0 5 0 0 5 5 5 1 AAA domain IstB_IS21 PF01695.12 EKG10223.1 - 4.2e-06 26.2 0.0 2.5 7.4 0.0 4.6 4 0 0 4 4 4 2 IstB-like ATP binding protein RuvB_N PF05496.7 EKG10223.1 - 4.6e-06 25.8 0.1 1.1 8.2 0.0 4.7 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EKG10223.1 - 2.4e-05 23.6 1.3 0.042 13.0 0.0 4.7 5 0 0 5 5 5 1 PhoH-like protein Torsin PF06309.6 EKG10223.1 - 8.2e-05 22.4 0.0 7.8 6.4 0.0 4.7 4 0 0 4 4 4 0 Torsin Sigma54_activat PF00158.21 EKG10223.1 - 0.00012 21.6 0.1 8 5.8 0.0 4.9 4 1 0 4 4 4 0 Sigma-54 interaction domain DUF2075 PF09848.4 EKG10223.1 - 0.00019 20.5 11.7 0.0013 17.7 0.0 6.4 8 0 0 8 8 8 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EKG10223.1 - 0.00073 18.9 5.5 0.15 11.4 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.1 EKG10223.1 - 0.0008 19.0 13.7 1.7 8.1 0.0 5.7 5 1 0 5 5 5 1 AAA domain AAA_28 PF13521.1 EKG10223.1 - 0.0037 17.2 7.8 18 5.2 0.0 5.3 5 0 0 5 5 4 0 AAA domain KaiC PF06745.8 EKG10223.1 - 0.018 14.1 2.0 6.2 5.8 0.0 4.0 4 0 0 4 4 4 0 KaiC Helicase_RecD PF05127.9 EKG10223.1 - 0.018 14.6 0.5 1.7 8.2 0.0 3.2 3 0 0 3 3 2 0 Helicase AAA_29 PF13555.1 EKG10223.1 - 0.06 12.8 0.5 69 3.0 0.0 4.0 4 0 0 4 4 4 0 P-loop containing region of AAA domain Guanylate_cyc_2 PF09778.4 EKG10223.1 - 0.16 11.1 0.0 16 4.5 0.0 2.5 2 0 0 2 2 2 0 Guanylylate cyclase MobB PF03205.9 EKG10223.1 - 0.17 11.6 0.8 42 3.8 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EKG10223.1 - 0.28 11.4 9.5 19 5.5 0.0 5.1 6 0 0 6 6 4 0 ABC transporter CRT10 PF08728.5 EKG10223.1 - 4.7 5.0 5.7 7.4 4.4 4.0 1.2 1 0 0 1 1 1 0 CRT10 CALCOCO1 PF07888.6 EKG10224.1 - 0.1 10.8 0.1 0.16 10.2 0.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3433 PF11915.3 EKG10225.1 - 3.1e-25 88.1 10.2 1.3e-16 60.5 0.4 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) MRAP PF15183.1 EKG10225.1 - 0.51 9.9 0.0 0.51 9.9 0.0 2.4 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family zf-C2H2_4 PF13894.1 EKG10226.1 - 0.049 13.9 1.0 0.9 10.0 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 EKG10229.1 - 3.4e-63 212.5 6.5 3.9e-32 111.4 0.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EKG10229.1 - 1.4e-32 112.7 1.1 1e-16 61.0 0.1 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EKG10229.1 - 4.1e-31 106.9 0.0 8.2e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain THF_DHG_CYH_C PF02882.14 EKG10229.1 - 0.00015 20.8 0.2 0.0047 16.0 0.2 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EKG10229.1 - 1.2 8.7 5.3 13 5.4 0.4 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PRK PF00485.13 EKG10230.1 - 0.0011 18.6 0.0 0.0031 17.0 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EKG10230.1 - 0.0025 18.6 0.1 0.14 12.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EKG10230.1 - 0.0033 16.2 0.0 0.0054 15.5 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EKG10230.1 - 0.01 15.8 0.6 0.056 13.4 0.4 2.2 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 EKG10230.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EKG10230.1 - 0.02 14.7 0.1 0.049 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EKG10230.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EKG10230.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Methyltransf_23 PF13489.1 EKG10231.1 - 4.4e-10 39.5 0.0 6.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10231.1 - 1.2e-06 28.9 0.0 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10231.1 - 3.9e-05 24.2 0.0 0.0005 20.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10231.1 - 5.9e-05 22.6 0.0 0.00025 20.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG10231.1 - 0.00077 19.4 0.0 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG10231.1 - 0.00086 19.7 0.0 0.002 18.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG10231.1 - 0.0025 16.8 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EKG10231.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MTS PF05175.9 EKG10231.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EKG10231.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Lipase_GDSL PF00657.17 EKG10232.1 - 4.4e-14 52.8 1.3 7.1e-14 52.1 0.9 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DPBB_1 PF03330.13 EKG10233.1 - 8.3e-10 38.5 0.1 2.1e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel TAT_signal PF10518.4 EKG10233.1 - 0.66 10.1 3.8 2 8.6 2.3 2.1 1 1 1 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence IBB PF01749.15 EKG10235.1 - 0.51 10.5 11.3 0.058 13.5 4.0 2.2 2 0 0 2 2 2 0 Importin beta binding domain zf-H2C2_2 PF13465.1 EKG10237.1 - 2.6e-10 40.0 16.5 1.1e-05 25.4 2.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EKG10237.1 - 3.4e-08 33.3 13.5 0.0012 19.0 2.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG10237.1 - 9.5e-06 25.6 12.7 0.014 15.7 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG10237.1 - 0.54 10.4 3.2 0.27 11.4 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_16 PF00722.16 EKG10244.1 - 2.2e-14 53.1 0.0 1.1e-13 50.8 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 BTB PF00651.26 EKG10246.1 - 0.00029 20.7 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain EMP24_GP25L PF01105.19 EKG10247.1 - 2.5e-41 141.4 0.0 3e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Lactamase_B PF00753.22 EKG10249.1 - 4.3e-22 78.7 0.5 5.7e-22 78.3 0.4 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG10249.1 - 1.7e-06 27.6 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG10249.1 - 0.094 12.4 0.6 0.44 10.2 0.4 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain NmrA PF05368.8 EKG10250.1 - 2.6e-14 53.0 0.8 1.9e-13 50.1 0.6 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG10250.1 - 1.7e-13 50.9 0.1 2.5e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG10250.1 - 5e-08 32.6 0.8 7.4e-06 25.5 0.2 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG10250.1 - 4.3e-06 25.8 0.6 4.4e-05 22.5 0.5 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 EKG10250.1 - 4.4e-05 23.2 0.1 6.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EKG10250.1 - 0.0011 19.3 0.4 0.0025 18.1 0.2 1.7 2 0 0 2 2 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EKG10250.1 - 0.0011 18.8 0.2 0.0019 18.1 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 EKG10250.1 - 0.0017 18.2 3.5 0.007 16.2 2.4 1.9 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EKG10250.1 - 0.0023 17.0 0.2 0.0038 16.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EKG10250.1 - 0.019 14.7 0.7 0.029 14.2 0.5 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EKG10250.1 - 0.029 14.9 0.3 0.1 13.1 0.2 1.9 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EKG10250.1 - 0.037 14.4 0.3 0.099 13.0 0.2 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EKG10250.1 - 0.039 13.9 0.6 0.076 13.0 0.4 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_3 PF03447.11 EKG10250.1 - 0.076 13.4 0.2 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain RNase_Zc3h12a PF11977.3 EKG10250.1 - 0.11 12.2 0.1 0.21 11.4 0.1 1.3 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain IlvN PF07991.7 EKG10250.1 - 0.12 11.7 1.0 0.18 11.1 0.3 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain PALP PF00291.20 EKG10251.1 - 7.7e-75 251.9 1.0 9.5e-75 251.6 0.7 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EKG10251.1 - 0.002 17.2 0.8 0.0031 16.6 0.5 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DFP PF04127.10 EKG10251.1 - 0.034 13.7 0.8 0.068 12.7 0.5 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Chitin_synth_1 PF01644.12 EKG10252.1 - 1.2e-67 226.7 0.0 1.8e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EKG10252.1 - 2.8e-28 97.3 0.0 5.3e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EKG10252.1 - 2.6e-25 88.8 0.1 1.1e-20 73.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EKG10252.1 - 7.3e-13 48.6 0.2 7.3e-13 48.6 0.1 2.5 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG10252.1 - 1.1e-09 38.3 0.0 3.2e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF218 PF02698.12 EKG10253.1 - 3.5e-06 26.5 0.0 5.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain UQ_con PF00179.21 EKG10254.1 - 5.9e-38 129.4 0.0 8.4e-38 128.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG10254.1 - 0.0083 15.8 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B eIF3_subunit PF08597.5 EKG10254.1 - 0.018 14.5 0.4 0.027 14.0 0.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit IlvN PF07991.7 EKG10255.1 - 5.3e-47 159.2 0.0 7.9e-47 158.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EKG10255.1 - 8.2e-46 155.5 0.0 1.4e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EKG10255.1 - 0.033 14.5 0.2 0.1 13.0 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EKG10255.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.13 EKG10257.1 - 0.22 11.4 7.8 0.39 10.6 5.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF-5_eIF-2B PF01873.12 EKG10259.1 - 3.5e-45 152.7 0.3 5.6e-45 152.0 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Lar_restr_allev PF14354.1 EKG10259.1 - 0.063 13.5 0.6 0.24 11.7 0.4 2.1 1 1 0 1 1 1 0 Restriction alleviation protein Lar Arc_trans_TRASH PF08394.5 EKG10259.1 - 1.4 9.1 7.1 1.1 9.4 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain DUF2201_N PF13203.1 EKG10259.1 - 2 7.4 7.8 3.3 6.8 5.4 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-HYPF PF07503.7 EKG10259.1 - 3.9 6.9 6.2 14 5.1 2.7 2.7 2 1 1 3 3 3 0 HypF finger AIM24 PF01987.12 EKG10260.1 - 4e-55 186.6 0.1 4.8e-55 186.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 AA_permease PF00324.16 EKG10261.1 - 3.3e-92 309.3 37.4 2.4e-75 253.6 14.0 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EKG10261.1 - 1.1e-21 76.9 36.3 1.8e-21 76.2 25.2 1.3 1 0 0 1 1 1 1 Amino acid permease ADH_N PF08240.7 EKG10262.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Tad PF13400.1 EKG10264.1 - 0.041 13.9 0.5 0.041 13.9 0.3 4.4 5 0 0 5 5 5 0 Putative Flp pilus-assembly TadE/G-like Peptidase_M35 PF02102.10 EKG10265.1 - 4.2e-10 38.8 0.2 6.5e-10 38.1 0.1 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family zf-C2H2_jaz PF12171.3 EKG10266.1 - 8.7e-10 38.4 0.2 1.9e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG10266.1 - 4.1e-07 29.9 0.3 4.1e-07 29.9 0.2 1.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EKG10266.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.2 EKG10266.1 - 0.046 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EKG10266.1 - 0.057 13.7 0.3 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Glyco_hydro_61 PF03443.9 EKG10268.1 - 4e-62 209.8 0.1 7.2e-62 209.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EKG10268.1 - 2e-10 40.1 12.9 5e-10 38.8 8.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Menin PF05053.8 EKG10268.1 - 9 4.3 7.1 13 3.8 4.9 1.2 1 0 0 1 1 1 0 Menin Ank_2 PF12796.2 EKG10269.1 - 3.8e-15 55.9 0.2 6.3e-09 36.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG10269.1 - 8.4e-11 41.7 0.0 1e-07 31.9 0.0 3.4 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EKG10269.1 - 6.5e-10 38.3 0.0 4.2e-06 26.3 0.0 3.8 4 0 0 4 4 3 2 Ankyrin repeat AAA_16 PF13191.1 EKG10269.1 - 1.3e-07 31.7 1.5 1.4e-06 28.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain Ank_3 PF13606.1 EKG10269.1 - 2.1e-07 30.5 0.0 0.00021 21.1 0.0 3.7 3 0 0 3 3 2 1 Ankyrin repeat NACHT PF05729.7 EKG10269.1 - 2.4e-07 30.5 0.0 7.9e-07 28.8 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EKG10269.1 - 4e-07 30.2 0.2 2.2e-06 27.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain Ank_4 PF13637.1 EKG10269.1 - 1.8e-05 25.0 0.1 0.00062 20.2 0.0 3.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) AAA_19 PF13245.1 EKG10269.1 - 0.0016 18.1 0.0 0.007 16.0 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 EKG10269.1 - 0.0032 17.7 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EKG10269.1 - 0.0068 15.8 0.0 0.025 13.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EKG10269.1 - 0.0074 15.8 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EKG10269.1 - 0.0075 16.5 0.0 0.046 14.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EKG10269.1 - 0.0089 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EKG10269.1 - 0.011 15.6 0.0 0.044 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EKG10269.1 - 0.013 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EKG10269.1 - 0.014 15.3 0.0 0.043 13.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 EKG10269.1 - 0.015 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG10269.1 - 0.025 15.4 1.9 0.41 11.4 1.3 3.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKG10269.1 - 0.039 13.3 0.0 0.11 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EKG10269.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EKG10269.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.12 EKG10269.1 - 0.093 12.2 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EKG10269.1 - 0.18 10.5 2.7 4 6.1 0.0 2.9 3 0 0 3 3 3 0 ArgK protein DPPIV_N PF00930.16 EKG10270.1 - 1.8e-107 358.9 3.7 2.5e-107 358.5 2.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EKG10270.1 - 1.8e-36 125.3 1.3 3.2e-36 124.5 0.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG10270.1 - 1.9e-05 24.4 0.1 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EKG10270.1 - 5.9e-05 22.6 2.0 0.13 11.9 0.0 4.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 EKG10270.1 - 0.00035 20.5 0.1 0.00089 19.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EKG10270.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold FixQ PF05545.6 EKG10271.1 - 0.8 9.3 6.4 3.8 7.2 0.3 3.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF515 PF04415.7 EKG10272.1 - 1.1 7.4 6.0 1.5 6.9 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) UQ_con PF00179.21 EKG10273.1 - 3.1e-43 146.5 0.0 3.5e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG10273.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B SNF2_N PF00176.18 EKG10274.1 - 2e-81 273.0 0.1 3.7e-81 272.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EKG10274.1 - 4.8e-46 155.3 3.0 1.6e-45 153.6 2.1 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EKG10274.1 - 7.5e-31 106.8 4.2 7.5e-31 106.8 2.9 3.8 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 EKG10274.1 - 2e-15 56.3 0.0 1.3e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG10274.1 - 5.6e-08 32.8 1.8 2.1e-07 30.9 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKG10274.1 - 3.3e-06 26.7 0.0 8.6e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EKG10274.1 - 0.036 13.9 0.1 0.15 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain DEAD_2 PF06733.10 EKG10274.1 - 0.071 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 DEAD_2 ArsA_ATPase PF02374.10 EKG10275.1 - 8.5e-117 389.5 0.2 9.8e-117 389.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EKG10275.1 - 1.4e-18 67.0 0.2 2.4e-18 66.2 0.2 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EKG10275.1 - 2.2e-09 37.4 0.1 4.9e-08 33.0 0.0 2.8 2 2 0 2 2 2 1 AAA domain SRP54 PF00448.17 EKG10275.1 - 9.2e-07 28.4 0.2 0.0002 20.8 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EKG10275.1 - 1.9e-06 27.2 0.0 4.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EKG10275.1 - 0.003 16.9 0.1 0.011 15.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG10275.1 - 0.0036 17.0 0.0 0.0077 15.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EKG10275.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein MipZ PF09140.6 EKG10275.1 - 0.0093 15.0 0.0 0.024 13.7 0.0 1.6 2 0 0 2 2 2 1 ATPase MipZ YhjQ PF06564.7 EKG10275.1 - 0.0099 15.2 0.0 0.026 13.9 0.0 1.6 2 0 0 2 2 2 1 YhjQ protein T2SE PF00437.15 EKG10275.1 - 0.015 14.2 0.0 0.045 12.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EKG10275.1 - 0.028 14.7 0.2 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EKG10275.1 - 0.03 13.7 0.1 0.047 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain PhoH PF02562.11 EKG10275.1 - 0.038 13.2 0.0 0.099 11.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein VirC1 PF07015.6 EKG10275.1 - 0.039 13.0 0.1 0.23 10.5 0.0 2.1 2 0 0 2 2 2 0 VirC1 protein NB-ARC PF00931.17 EKG10275.1 - 0.04 12.7 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EKG10275.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.1 EKG10275.1 - 0.13 11.8 0.0 0.63 9.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EKG10275.1 - 0.14 11.2 0.2 0.57 9.2 0.0 2.0 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 EKG10275.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin A1_Propeptide PF07966.7 EKG10275.1 - 0.24 11.2 1.0 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 A1 Propeptide Lipase_3 PF01764.20 EKG10276.1 - 6.3e-35 119.8 0.0 9.2e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 EKG10276.1 - 1.8e-07 30.8 0.1 3.5e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_5 PF12695.2 EKG10276.1 - 0.00011 22.0 0.2 0.00025 20.8 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG10276.1 - 0.00038 20.3 0.1 0.00054 19.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EKG10276.1 - 0.00047 19.9 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Cutinase Abhydrolase_8 PF06259.7 EKG10276.1 - 0.0046 16.4 0.1 0.013 15.0 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase DUF2974 PF11187.3 EKG10276.1 - 0.0049 16.2 0.4 0.016 14.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) DUF676 PF05057.9 EKG10276.1 - 0.007 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 EKG10276.1 - 0.017 15.3 0.1 0.027 14.6 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EKG10276.1 - 0.024 14.0 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase YjeF_N PF03853.10 EKG10276.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus PGAP1 PF07819.8 EKG10276.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 EKG10276.1 - 0.085 12.4 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S8 PF00082.17 EKG10277.1 - 8.4e-28 97.3 4.6 8.6e-27 93.9 3.2 2.0 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EKG10277.1 - 0.0041 17.6 0.0 0.0079 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 p450 PF00067.17 EKG10278.1 - 1.7e-14 53.2 0.0 1.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EthD PF07110.6 EKG10279.1 - 0.00016 22.5 0.0 0.00022 22.1 0.0 1.2 1 0 0 1 1 1 1 EthD domain Acyl_transf_3 PF01757.17 EKG10281.1 - 1.1e-14 54.1 27.3 3.8e-14 52.2 18.9 1.8 1 1 0 1 1 1 1 Acyltransferase family adh_short PF00106.20 EKG10283.1 - 8.4e-19 68.0 3.5 7.9e-18 64.9 2.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10283.1 - 1.1e-08 35.2 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG10283.1 - 5.8e-05 22.8 3.1 0.00021 21.0 2.2 1.9 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EKG10283.1 - 0.00035 20.3 0.8 0.0013 18.4 0.4 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG10283.1 - 0.00051 19.5 0.1 0.0011 18.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG10283.1 - 0.57 10.1 3.0 31 4.5 2.1 2.2 1 1 0 1 1 1 0 NADH(P)-binding F-box-like_2 PF13013.1 EKG10285.1 - 0.0057 16.3 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like domain MFS_1 PF07690.11 EKG10286.1 - 1.5e-30 106.1 28.3 1.5e-30 106.1 19.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG10286.1 - 4e-05 22.1 7.8 4e-05 22.1 5.4 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein Orbi_VP5 PF00901.12 EKG10287.1 - 0.14 10.3 0.2 0.18 9.9 0.2 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ribosomal_60s PF00428.14 EKG10287.1 - 1.1 9.7 6.3 1.2 9.6 3.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PepSY_2 PF13670.1 EKG10287.1 - 1.5 8.7 6.8 0.88 9.5 2.3 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Glyco_hydro_43 PF04616.9 EKG10288.1 - 4.2e-37 127.7 2.0 5.7e-37 127.3 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Aldo_ket_red PF00248.16 EKG10289.1 - 1.9e-21 76.1 0.0 5.1e-21 74.7 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Ank_5 PF13857.1 EKG10290.1 - 2e-05 24.6 0.0 0.01 16.0 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG10290.1 - 0.025 14.9 0.0 1.2 9.4 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) Ank PF00023.25 EKG10290.1 - 0.047 13.5 0.0 26 4.8 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat Ank_4 PF13637.1 EKG10290.1 - 0.069 13.6 0.0 28 5.3 0.0 3.9 4 0 0 4 4 4 0 Ankyrin repeats (many copies) MR_MLE_C PF13378.1 EKG10291.1 - 2.1e-19 69.5 0.0 5.5e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EKG10291.1 - 1.4e-13 51.1 0.0 9e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EKG10291.1 - 0.00051 20.0 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EKG10291.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus CUE PF02845.11 EKG10292.1 - 4.2e-11 42.1 0.0 6e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 CUE domain Metal_resist PF13801.1 EKG10292.1 - 0.066 13.2 3.9 1.4 8.9 0.6 2.4 2 0 0 2 2 2 0 Heavy-metal resistance NUDIX PF00293.23 EKG10293.1 - 1.6e-23 82.8 0.1 2e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EKG10293.1 - 0.031 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 NUDIX domain PHP PF02811.14 EKG10294.1 - 4.8e-16 59.0 0.1 1.4e-15 57.5 0.1 1.7 1 1 0 1 1 1 1 PHP domain FKBP_C PF00254.23 EKG10295.1 - 3.9e-25 87.7 0.0 4.6e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase adh_short PF00106.20 EKG10296.1 - 1.9e-19 70.1 0.7 7.1e-19 68.3 0.7 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG10296.1 - 3.5e-09 36.5 0.7 5.8e-09 35.8 0.5 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG10296.1 - 1.3e-06 27.9 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG10296.1 - 3.9e-05 22.6 0.0 5.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EKG10296.1 - 0.019 15.0 0.1 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding Sds3 PF08598.6 EKG10298.1 - 1.3e-45 155.4 7.2 3.7e-45 153.9 5.0 1.8 1 1 0 1 1 1 1 Sds3-like ORC5_C PF14630.1 EKG10298.1 - 0.0076 15.7 0.4 0.019 14.4 0.0 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus DNA_topoisoIV PF00521.15 EKG10299.1 - 1.3e-125 419.6 0.2 3.1e-125 418.3 0.1 1.7 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EKG10299.1 - 1.5e-35 121.9 5.2 1.5e-35 121.9 3.6 2.5 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EKG10299.1 - 6e-14 51.8 0.0 2.8e-13 49.7 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EKG10299.1 - 6.3e-10 38.7 0.0 1.8e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VASP_tetra PF08776.6 EKG10299.1 - 0.00076 18.7 1.0 0.0026 17.0 0.7 1.9 1 0 0 1 1 1 1 VASP tetramerisation domain RNA_pol_I_TF PF04090.7 EKG10300.1 - 0.013 14.8 0.0 0.11 11.7 0.0 2.1 1 1 0 1 1 1 0 RNA polymerase I specific initiation factor zf-RING_2 PF13639.1 EKG10301.1 - 2.3e-15 56.1 5.5 3.6e-15 55.5 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKG10301.1 - 4.2e-10 39.5 1.2 6.6e-10 38.9 0.8 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKG10301.1 - 1.9e-09 37.3 4.1 3e-09 36.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG10301.1 - 2.9e-08 33.2 3.8 4.4e-08 32.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG10301.1 - 1e-07 31.5 3.1 1.5e-07 30.9 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG10301.1 - 1.8e-06 27.5 2.2 2.9e-06 26.8 1.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EKG10301.1 - 0.0002 21.1 2.1 0.00047 19.9 1.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EKG10301.1 - 0.00037 20.1 2.2 0.00081 19.0 1.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.2 EKG10301.1 - 0.0048 16.9 6.2 0.0074 16.3 4.3 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 EKG10301.1 - 0.017 14.7 3.5 0.027 14.0 2.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EKG10301.1 - 0.028 14.2 4.5 0.46 10.3 3.2 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EKG10301.1 - 0.036 13.5 1.3 0.07 12.6 0.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EKG10301.1 - 0.077 12.9 3.5 0.14 12.1 2.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EKG10301.1 - 0.25 10.8 1.1 0.53 9.8 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.6 EKG10301.1 - 1.7 8.6 4.1 3 7.8 2.9 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.1 EKG10301.1 - 2.3 8.0 4.2 1.6 8.5 1.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Fungal_trans_2 PF11951.3 EKG10302.1 - 7.1e-16 57.7 0.0 1.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG10302.1 - 5.9e-08 32.4 9.7 1.3e-07 31.3 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAR_2 PF10455.4 EKG10304.1 - 5.7e-64 215.7 0.4 8.2e-64 215.2 0.3 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EKG10304.1 - 5e-20 72.0 2.2 7.2e-19 68.2 1.5 2.0 1 1 0 1 1 1 1 BAR domain zf-C4H2 PF10146.4 EKG10304.1 - 0.12 12.3 2.8 0.2 11.6 0.7 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein Sugar_tr PF00083.19 EKG10305.1 - 5.6e-75 252.6 22.8 6.9e-75 252.3 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG10305.1 - 3.1e-22 78.7 43.1 1.2e-18 67.0 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily KH_3 PF13014.1 EKG10307.1 - 0.00097 18.7 0.0 0.0046 16.5 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_1 PF00013.24 EKG10307.1 - 0.0039 16.7 0.1 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 KH domain CT47 PF15623.1 EKG10307.1 - 0.032 13.9 12.0 0.038 13.7 8.3 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 OPT PF03169.10 EKG10308.1 - 5e-65 220.1 12.4 5.9e-65 219.9 8.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 EKG10308.1 - 0.23 10.5 0.5 1.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3093 PF11292.3 EKG10308.1 - 6.1 6.6 5.9 1.8 8.3 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) NmrA PF05368.8 EKG10309.1 - 2.6e-23 82.5 0.0 3.7e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG10309.1 - 1.6e-13 51.1 0.0 2.2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EKG10309.1 - 1.2e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EKG10309.1 - 0.0013 18.1 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EKG10309.1 - 0.024 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EKG10309.1 - 0.051 12.4 0.0 2.1 7.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain YcfA PF07927.7 EKG10309.1 - 0.075 12.9 0.2 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 YcfA-like protein DapB_N PF01113.15 EKG10309.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.1 EKG10309.1 - 0.12 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 6PGD PF00393.14 EKG10310.1 - 4.2e-65 219.8 0.0 5.6e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EKG10310.1 - 9.3e-36 123.1 0.0 1.3e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EKG10310.1 - 6.9e-07 29.0 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EKG10310.1 - 8.6e-06 25.5 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EKG10310.1 - 0.00035 20.0 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EKG10310.1 - 0.00083 18.7 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EKG10310.1 - 0.0012 19.2 0.0 0.0035 17.7 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EKG10310.1 - 0.015 14.4 0.4 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 EKG10310.1 - 0.029 14.4 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase zf-C2H2_2 PF12756.2 EKG10310.1 - 0.12 12.4 0.1 0.41 10.7 0.0 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) GFO_IDH_MocA PF01408.17 EKG10310.1 - 0.13 12.8 0.1 0.51 10.8 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Amidase PF01425.16 EKG10311.1 - 5.6e-33 114.4 0.7 1e-32 113.5 0.5 1.4 1 0 0 1 1 1 1 Amidase Pkinase PF00069.20 EKG10312.1 - 6.3e-54 182.8 0.0 9.1e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG10312.1 - 5.4e-25 87.9 0.0 4.2e-24 85.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG10312.1 - 0.0013 17.7 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG10312.1 - 0.012 15.3 0.4 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pro-kuma_activ PF09286.6 EKG10313.1 - 4e-40 137.1 0.0 7.3e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EKG10313.1 - 9.1e-07 28.2 0.2 1.7e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Subtilase family Peptidase_S10 PF00450.17 EKG10314.1 - 1.1e-86 291.5 0.2 1.6e-86 291.0 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase AIG2 PF06094.7 EKG10315.1 - 1.7e-06 28.4 0.0 2.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 EKG10315.1 - 0.00025 21.0 0.3 0.0016 18.4 0.1 2.3 2 1 0 2 2 2 1 AIG2-like family RRM_6 PF14259.1 EKG10316.1 - 3.4e-21 75.0 0.0 1.6e-10 40.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG10316.1 - 4e-21 74.4 0.0 9.7e-13 47.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG10316.1 - 2.3e-05 24.1 0.0 0.046 13.5 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-3c_N PF05470.7 EKG10316.1 - 0.013 13.6 0.8 4.6 5.2 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SPT6_acidic PF14632.1 EKG10316.1 - 0.023 14.8 2.3 0.023 14.8 1.6 4.5 4 1 1 5 5 5 0 Acidic N-terminal SPT6 zf-CCHC PF00098.18 EKG10317.1 - 6.3 6.9 35.3 1.6 8.8 0.6 5.2 6 0 0 6 6 6 0 Zinc knuckle Asp PF00026.18 EKG10318.1 - 1.2e-67 228.4 7.1 1.4e-67 228.2 5.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKG10318.1 - 1.4e-08 34.8 0.3 4.3e-08 33.2 0.2 1.8 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EKG10318.1 - 0.00055 20.3 4.5 0.39 11.2 0.2 3.3 2 1 0 2 2 2 2 Aspartyl protease Sdh5 PF03937.11 EKG10320.1 - 2.3e-24 84.8 0.3 6.1e-24 83.4 0.1 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase adh_short PF00106.20 EKG10321.1 - 1.4e-16 60.8 0.1 1.8e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10321.1 - 1.6e-16 60.8 0.0 2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG10321.1 - 2.1e-06 27.5 0.3 3.7e-06 26.7 0.2 1.3 1 1 0 1 1 1 1 KR domain Peptidase_M20 PF01546.23 EKG10323.1 - 9.2e-32 110.0 0.0 1.6e-31 109.3 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EKG10323.1 - 1.5e-11 44.0 0.0 2.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Glyco_hydro_71 PF03659.9 EKG10325.1 - 3.3e-50 170.6 10.3 5.4e-50 169.9 7.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SpvB PF03534.8 EKG10325.1 - 0.0032 16.5 0.0 0.0068 15.4 0.0 1.5 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein DUF883 PF05957.8 EKG10327.1 - 0.048 14.0 4.7 0.39 11.1 3.2 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FoP_duplication PF13865.1 EKG10327.1 - 0.049 14.0 0.6 0.096 13.1 0.4 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF148 PF02520.12 EKG10327.1 - 0.075 12.8 1.2 0.17 11.7 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF148 Apolipoprotein PF01442.13 EKG10327.1 - 0.078 12.4 0.4 0.15 11.5 0.2 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2317 PF10079.4 EKG10327.1 - 0.22 10.0 2.4 0.25 9.9 1.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Pex24p PF06398.6 EKG10328.1 - 0.00013 20.9 5.7 0.00013 20.9 3.9 1.7 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin TPP_enzyme_M PF00205.17 EKG10330.1 - 2.7e-19 69.2 0.0 4.8e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EKG10330.1 - 3.2e-11 43.0 0.1 7.4e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EKG10330.1 - 2.9e-06 26.8 0.8 0.0003 20.3 0.2 3.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Med3 PF11593.3 EKG10331.1 - 0.013 14.7 3.2 0.017 14.3 2.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Sugar_tr PF00083.19 EKG10332.1 - 3.1e-70 237.0 28.6 3.6e-70 236.8 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG10332.1 - 4.9e-20 71.5 29.8 4.9e-20 71.5 20.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Viral_P18 PF04521.8 EKG10332.1 - 0.14 11.6 0.5 0.26 10.7 0.3 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Meth_synt_2 PF01717.13 EKG10333.1 - 0.00062 18.8 0.0 0.00087 18.3 0.0 1.4 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain RTA1 PF04479.8 EKG10334.1 - 9.8e-52 175.6 8.9 9.8e-52 175.6 6.2 1.5 2 0 0 2 2 2 1 RTA1 like protein Cation_ATPase_C PF00689.16 EKG10334.1 - 3.9 6.9 15.4 3 7.3 1.5 3.1 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus PalH PF08733.5 EKG10334.1 - 4.6 5.9 15.4 3.9 6.2 5.1 2.1 1 1 0 2 2 2 0 PalH/RIM21 DUF2975 PF11188.3 EKG10334.1 - 6 6.5 20.7 1.1 8.9 4.8 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2975) Cupin_1 PF00190.17 EKG10335.1 - 2.9e-26 91.6 0.2 4.9e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EKG10335.1 - 3.3e-25 87.3 0.3 1.5e-13 50.0 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EKG10335.1 - 8.1e-11 41.1 0.0 1.6e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EKG10335.1 - 2.2e-06 27.4 0.7 0.0022 17.6 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EKG10335.1 - 8e-05 22.3 0.1 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 Cupin FdtA PF05523.6 EKG10335.1 - 0.00031 20.2 0.0 0.083 12.3 0.0 2.2 2 0 0 2 2 2 2 WxcM-like, C-terminal MannoseP_isomer PF01050.13 EKG10335.1 - 0.00042 19.9 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 EKG10335.1 - 0.0015 17.9 0.0 0.0041 16.5 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase ARD PF03079.9 EKG10335.1 - 0.02 14.8 0.0 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 ARD/ARD' family 2OG-FeII_Oxy_5 PF13759.1 EKG10335.1 - 0.04 14.1 0.2 3.5 7.9 0.1 3.1 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Glyco_tran_28_C PF04101.11 EKG10336.1 - 1.7e-16 60.3 0.1 5.7e-16 58.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EKG10336.1 - 0.00075 18.7 0.0 0.00091 18.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 MRP-S28 PF10213.4 EKG10337.1 - 1.6e-43 147.8 0.1 2.4e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF3323 PF11796.3 EKG10337.1 - 0.013 14.8 0.2 0.055 12.7 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) FAM176 PF14851.1 EKG10337.1 - 0.013 15.1 1.1 0.016 14.8 0.0 1.7 2 0 0 2 2 2 0 FAM176 family GBP_repeat PF02526.9 EKG10337.1 - 0.042 13.2 0.0 1.7 8.1 0.0 2.5 2 0 0 2 2 2 0 Glycophorin-binding protein YtzH PF14165.1 EKG10338.1 - 0.039 14.1 0.0 0.71 10.1 0.0 2.2 2 0 0 2 2 2 0 YtzH-like protein R3H PF01424.17 EKG10338.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 R3H domain EHN PF06441.7 EKG10339.1 - 2e-33 114.6 0.4 4.3e-33 113.5 0.1 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG10339.1 - 8.4e-06 25.8 1.4 3.3e-05 23.8 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG10339.1 - 1.1e-05 25.0 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold NUDIX PF00293.23 EKG10341.1 - 7.6e-05 22.3 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain F-box PF00646.28 EKG10342.1 - 0.028 14.0 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain Lipase_GDSL PF00657.17 EKG10343.1 - 7.8e-15 55.3 1.4 1.1e-14 54.8 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase 2OG-FeII_Oxy_3 PF13640.1 EKG10344.1 - 1.9e-07 31.5 0.0 3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EKG10344.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ZZ PF00569.12 EKG10345.1 - 2e-18 65.6 53.4 1.2e-05 24.7 5.3 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type CsgE PF10627.4 EKG10345.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Curli assembly protein CsgE APG6 PF04111.7 EKG10345.1 - 0.32 9.9 4.8 0.51 9.3 3.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EKG10345.1 - 0.51 8.1 3.3 0.74 7.6 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.8 EKG10345.1 - 1.5 7.3 4.1 2.5 6.7 2.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FUSC PF04632.7 EKG10345.1 - 3.2 6.0 5.7 4.9 5.4 3.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAD_2 PF13419.1 EKG10346.1 - 1.4e-10 41.6 0.0 1.6e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG10346.1 - 1.3e-06 28.0 0.1 3.3e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EKG10346.1 - 0.00016 22.1 0.0 0.00019 21.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-H2C2_2 PF13465.1 EKG10347.1 - 8.9e-09 35.2 16.0 1.3e-06 28.3 3.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG10347.1 - 2.4e-06 27.4 17.4 0.00086 19.4 4.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EKG10347.1 - 0.011 15.8 5.3 0.024 14.7 3.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EKG10347.1 - 0.012 15.9 25.2 0.016 15.5 5.2 3.1 3 0 0 3 3 2 0 Zinc finger, C2H2 type Zn_Tnp_IS1595 PF12760.2 EKG10347.1 - 0.034 13.9 3.7 0.065 13.0 2.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Elf1 PF05129.8 EKG10347.1 - 0.082 12.6 0.2 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.1 EKG10347.1 - 0.19 11.4 6.7 1 9.1 1.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EKG10347.1 - 1.1 9.0 16.4 1.3 8.8 4.6 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EKG10347.1 - 1.2 9.1 7.5 2.1 8.3 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EKG10347.1 - 2.1 8.5 9.3 3.8 7.6 1.3 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EKG10347.1 - 2.3 8.4 8.9 0.23 11.6 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG10347.1 - 3.7 7.8 9.1 2.7 8.3 1.3 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type RTA1 PF04479.8 EKG10348.1 - 4.3e-39 134.3 5.7 5.9e-39 133.8 4.0 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF588 PF04535.7 EKG10348.1 - 0.073 12.6 8.8 1.1 8.7 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF588) Nrap PF03813.9 EKG10348.1 - 0.14 9.6 0.0 0.19 9.2 0.0 1.0 1 0 0 1 1 1 0 Nrap protein PGG PF13962.1 EKG10348.1 - 7.1 6.2 15.1 0.99 9.0 0.5 3.6 2 1 2 4 4 4 0 Domain of unknown function MFS_1 PF07690.11 EKG10349.1 - 9.1e-44 149.5 48.4 9.1e-44 149.5 33.5 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 EKG10350.1 - 1.1e-21 77.4 0.0 1.5e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10350.1 - 8.8e-11 42.0 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG10350.1 - 9.8e-07 28.9 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG10350.1 - 5.1e-06 26.2 0.0 1e-05 25.2 0.0 1.5 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 EKG10350.1 - 0.00024 20.2 0.1 0.0014 17.7 0.0 1.8 2 0 0 2 2 2 1 Saccharopine dehydrogenase Epimerase PF01370.16 EKG10350.1 - 0.0028 17.1 0.0 0.0056 16.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EKG10350.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1776 PF08643.5 EKG10350.1 - 0.034 13.2 0.2 0.067 12.3 0.1 1.4 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EKG10350.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EKG10350.1 - 0.13 12.0 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GMC_oxred_N PF00732.14 EKG10352.1 - 6.3e-30 104.3 0.0 3.3e-21 75.7 0.0 3.1 3 0 0 3 3 3 3 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG10352.1 - 0.00027 19.8 0.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EKG10352.1 - 0.00029 20.7 0.0 0.00078 19.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG10352.1 - 0.00042 19.3 0.1 0.26 10.1 0.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG10352.1 - 0.00078 19.3 0.0 0.0038 17.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG10352.1 - 0.0029 17.6 0.0 0.55 10.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG10352.1 - 0.0036 16.2 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EKG10352.1 - 0.071 11.5 0.7 0.11 10.9 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EKG10352.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain UQ_con PF00179.21 EKG10354.1 - 2.2e-43 147.0 0.0 3.2e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EKG10354.1 - 2.9e-06 26.7 0.0 5.4e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EKG10354.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKG10354.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain UBA_2 PF08587.6 EKG10354.1 - 0.045 13.9 0.4 0.14 12.4 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin associated domain (UBA) AAA PF00004.24 EKG10355.1 - 1.9e-41 141.3 0.0 3.6e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG10355.1 - 1.6e-06 28.2 0.2 0.00059 19.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKG10355.1 - 2.9e-06 27.3 0.0 5.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EKG10355.1 - 2.3e-05 23.4 0.0 4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EKG10355.1 - 3.1e-05 23.7 0.0 0.0001 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EKG10355.1 - 0.00054 19.0 0.0 0.00094 18.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKG10355.1 - 0.0014 18.6 1.2 0.0025 17.8 0.1 2.0 2 1 0 2 2 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EKG10355.1 - 0.0026 16.8 0.0 0.0059 15.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EKG10355.1 - 0.0073 15.9 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EKG10355.1 - 0.0089 15.7 0.2 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EKG10355.1 - 0.01 15.7 0.5 0.032 14.1 0.1 2.0 2 1 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EKG10355.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EKG10355.1 - 0.011 15.3 0.2 0.71 9.5 0.0 2.6 2 1 1 3 3 3 0 NACHT domain TIP49 PF06068.8 EKG10355.1 - 0.012 14.3 0.8 0.019 13.6 0.0 1.8 2 1 0 2 2 2 0 TIP49 C-terminus AAA_14 PF13173.1 EKG10355.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKG10355.1 - 0.015 16.1 0.3 0.045 14.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EKG10355.1 - 0.017 14.2 0.2 0.38 9.8 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_33 PF13671.1 EKG10355.1 - 0.023 14.5 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKG10355.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EKG10355.1 - 0.03 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EKG10355.1 - 0.033 13.5 1.4 0.36 10.2 0.3 2.3 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EKG10355.1 - 0.042 13.0 1.3 0.22 10.6 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EKG10355.1 - 0.045 12.9 0.1 0.088 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EKG10355.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EKG10355.1 - 0.14 11.7 1.9 0.15 11.5 0.2 1.8 2 0 0 2 2 2 0 AAA domain DUF1965 PF09248.5 EKG10356.1 - 5.7e-32 109.4 0.3 1e-31 108.6 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.15 EKG10356.1 - 8.3e-07 28.0 0.0 1.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EKG10356.1 - 0.00024 21.1 0.0 0.00073 19.5 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.15 EKG10357.1 - 1.5e-57 195.2 2.6 1.9e-57 194.8 1.8 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF3328 PF11807.3 EKG10358.1 - 1.7e-29 103.0 2.9 2.1e-29 102.7 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S10 PF00450.17 EKG10359.1 - 2.8e-77 260.6 3.9 2.9e-50 171.6 2.4 2.8 1 1 1 2 2 2 2 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EKG10359.1 - 1e-05 25.5 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EKG10360.1 - 1.1e-65 222.4 0.0 1.4e-65 222.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG10360.1 - 0.0012 18.4 0.0 0.61 9.6 0.0 2.7 3 0 0 3 3 3 2 alpha/beta hydrolase fold COesterase PF00135.23 EKG10361.1 - 9.7e-74 248.9 0.1 1.3e-73 248.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG10361.1 - 9.3e-11 41.6 0.5 4.5e-10 39.4 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG10361.1 - 3.2e-05 23.2 0.1 5.2e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG10361.1 - 0.0014 18.3 0.2 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.4 EKG10361.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SET PF00856.23 EKG10362.1 - 2.2e-07 31.3 0.1 2.2e-07 31.3 0.0 3.2 2 1 0 2 2 2 1 SET domain ETC_C1_NDUFA5 PF04716.9 EKG10363.1 - 2e-23 81.6 0.7 4.5e-23 80.5 0.5 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2852 PF11014.3 EKG10363.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Thioredoxin PF00085.15 EKG10364.1 - 2.4e-43 146.0 0.1 7.3e-25 86.6 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EKG10364.1 - 3.3e-16 59.6 0.0 1.5e-05 24.9 0.0 4.2 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKG10364.1 - 1.8e-08 34.3 0.1 0.0023 17.9 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EKG10364.1 - 1.9e-06 28.0 5.0 0.0054 16.9 0.1 4.6 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EKG10364.1 - 1e-05 25.4 0.9 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EKG10364.1 - 0.0046 16.7 0.1 0.22 11.3 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin domain HyaE PF07449.6 EKG10364.1 - 0.0064 16.3 0.0 2.6 8.0 0.0 2.9 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 EKG10364.1 - 3.4 7.6 8.5 0.37 10.7 0.1 3.2 4 0 0 4 4 4 0 Thioredoxin Rhodanese PF00581.15 EKG10366.1 - 5.5e-13 49.2 0.0 7.5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain MGC-24 PF05283.6 EKG10366.1 - 1.5 8.5 4.1 2.2 8.0 2.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) GKAP PF03359.8 EKG10367.1 - 0.0035 16.9 1.0 0.0041 16.7 0.7 1.1 1 0 0 1 1 1 1 Guanylate-kinase-associated protein (GKAP) protein Imm5 PF14423.1 EKG10367.1 - 0.0052 16.4 0.1 0.0059 16.2 0.1 1.0 1 0 0 1 1 1 1 Immunity protein Imm5 ImcF-related_N PF14331.1 EKG10367.1 - 0.0083 15.0 0.8 0.0086 15.0 0.5 1.0 1 0 0 1 1 1 1 ImcF-related N-terminal domain DUF3384 PF11864.3 EKG10367.1 - 0.053 11.9 0.3 0.064 11.7 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) Erp_C PF06780.6 EKG10367.1 - 0.12 12.2 0.4 0.15 11.8 0.3 1.1 1 0 0 1 1 1 0 Erp protein C-terminus YfcL PF08891.6 EKG10367.1 - 0.13 12.2 0.2 0.31 11.0 0.0 1.7 1 1 0 1 1 1 0 YfcL protein Dehydratase_LU PF02286.10 EKG10369.1 - 0.44 8.7 2.7 0.57 8.3 1.8 1.1 1 0 0 1 1 1 0 Dehydratase large subunit 4HBT PF03061.17 EKG10370.1 - 8.4e-05 22.6 0.6 0.00021 21.3 0.0 1.9 2 1 0 2 2 2 1 Thioesterase superfamily p450 PF00067.17 EKG10371.1 - 1.1e-66 225.3 0.0 1.4e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF615 PF04751.9 EKG10371.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF615) MerR PF00376.18 EKG10372.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 MerR family regulatory protein AMP-binding PF00501.23 EKG10373.1 - 0 2496.0 15.5 1.4e-91 306.9 0.1 10.4 9 1 0 9 9 9 9 AMP-binding enzyme Condensation PF00668.15 EKG10373.1 - 0 1371.7 0.0 3.2e-48 164.1 0.0 9.5 9 0 0 9 9 9 9 Condensation domain PP-binding PF00550.20 EKG10373.1 - 5.1e-122 398.2 24.6 4.5e-13 49.2 0.1 10.9 10 0 0 10 10 10 10 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 EKG10373.1 - 5.5e-38 130.3 0.0 2e-36 125.2 0.0 2.5 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EKG10373.1 - 9e-06 25.2 0.1 3.2e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 EKG10373.1 - 0.0023 18.2 5.2 0.071 13.4 0.0 4.9 5 0 0 5 5 5 1 HxxPF-repeated domain Phg_2220_C PF09524.5 EKG10373.1 - 0.014 15.3 0.4 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) 3Beta_HSD PF01073.14 EKG10373.1 - 0.015 14.0 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3236 PF11576.3 EKG10373.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) GH3 PF03321.8 EKG10373.1 - 0.26 9.7 1.1 93 1.3 0.0 4.5 5 0 0 5 5 5 0 GH3 auxin-responsive promoter Sigma54_DBD PF04552.8 EKG10373.1 - 0.47 9.9 0.0 1.5e+02 1.8 0.0 3.8 4 0 0 4 4 4 0 Sigma-54, DNA binding domain Csm1 PF12539.3 EKG10373.1 - 0.9 10.0 8.7 7.3 7.1 0.0 6.0 8 0 0 8 8 7 0 Chromosome segregation protein Csm1/Pcs1 Transferase PF02458.10 EKG10373.1 - 2.7 6.3 0.0 33 2.7 0.0 2.5 2 0 0 2 2 2 0 Transferase family AATase PF07247.7 EKG10373.1 - 3 6.2 0.0 85 1.4 0.0 3.0 4 0 0 4 4 4 0 Alcohol acetyltransferase PP1_inhibitor PF05361.7 EKG10373.1 - 4 7.1 0.0 8.4 6.0 0.0 1.4 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor Orthopox_B11R PF07033.6 EKG10373.1 - 7.2 6.1 1.5 14 5.2 0.2 2.0 2 0 0 2 2 2 0 Orthopoxvirus B11R protein DREPP PF05558.7 EKG10373.1 - 9.6 5.9 1.1 23 4.7 0.8 1.5 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide ketoacyl-synt PF00109.21 EKG10376.1 - 3.1e-20 72.7 3.5 3.1e-20 72.7 2.4 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EKG10376.1 - 6.4e-17 62.1 0.0 1.6e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EKG10376.1 - 2.6e-12 46.6 0.0 7e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Lamp PF01299.12 EKG10376.1 - 1.6 7.8 4.2 2.8 6.9 2.9 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) 2OG-Fe_Oxy_2 PF10014.4 EKG10377.1 - 2e-45 154.5 0.5 2.8e-45 154.1 0.3 1.2 1 0 0 1 1 1 1 2OG-Fe dioxygenase ABC_tran PF00005.22 EKG10378.1 - 2.9e-10 40.5 0.0 5.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EKG10378.1 - 0.00091 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EKG10378.1 - 0.0027 17.7 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EKG10378.1 - 0.0059 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EKG10378.1 - 0.0094 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKG10378.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EKG10378.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EKG10378.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EKG10378.1 - 0.025 13.4 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EKG10378.1 - 0.04 13.4 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EKG10378.1 - 0.063 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.14 EKG10378.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EKG10378.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKG10378.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EKG10378.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Dynamin family Rad17 PF03215.10 EKG10378.1 - 0.15 10.7 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EKG10379.1 - 1.1e-26 93.7 0.0 1.8e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EKG10379.1 - 8.8e-10 38.4 0.5 1.2e-09 37.9 0.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EKG10379.1 - 4.2e-05 22.8 0.8 0.0054 15.9 0.1 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EKG10379.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EKG10379.1 - 0.019 14.3 0.2 0.98 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EKG10379.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 EKG10379.1 - 0.024 13.3 0.1 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 EKG10379.1 - 0.027 14.5 0.1 0.21 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKG10379.1 - 0.058 12.7 0.1 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EKG10379.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EKG10379.1 - 0.12 12.7 0.0 0.45 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKG10379.1 - 0.13 12.2 0.0 4.1 7.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain ABC1 PF03109.11 EKG10380.1 - 5.9e-24 84.3 0.1 1.2e-23 83.2 0.1 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EKG10380.1 - 3.5e-05 23.6 1.0 0.055 13.2 0.0 3.0 1 1 2 3 3 3 2 Phosphotransferase enzyme family DUF1834 PF08873.6 EKG10380.1 - 0.072 12.6 0.1 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) Aldolase_II PF00596.16 EKG10381.1 - 1.6e-43 148.4 0.1 2.2e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HAD_2 PF13419.1 EKG10382.1 - 2.4e-31 109.3 0.0 3.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG10382.1 - 0.003 17.7 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG10382.1 - 0.01 16.2 0.0 0.33 11.3 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase bZIP_1 PF00170.16 EKG10383.1 - 5.2e-06 26.3 6.4 5.2e-06 26.3 4.5 2.0 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EKG10383.1 - 0.0024 17.6 7.4 0.0055 16.5 5.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper CysG_dimeriser PF10414.4 EKG10383.1 - 0.051 13.0 1.4 7.2 6.1 0.4 2.6 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region Lactamase_B_2 PF12706.2 EKG10385.1 - 1.5e-34 119.2 0.2 2.1e-34 118.7 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG10385.1 - 3.3e-10 39.9 0.1 9.7e-10 38.3 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG10385.1 - 0.00062 19.4 3.4 0.0024 17.5 0.1 2.7 2 1 1 3 3 3 1 Metallo-beta-lactamase superfamily Nucleoplasmin PF03066.10 EKG10385.1 - 0.11 12.0 1.1 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin Thioesterase PF00975.15 EKG10386.1 - 1.6e-13 51.3 0.1 2.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EKG10386.1 - 8.4e-09 35.6 4.0 1.1e-08 35.2 2.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG10386.1 - 0.0009 19.0 0.0 0.002 17.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG10386.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EKG10386.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.21 EKG10387.1 - 2.9e-65 220.2 0.0 4.2e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG10387.1 - 9.4e-16 57.7 0.1 1.8e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Collagen PF01391.13 EKG10387.1 - 8.2e-05 22.0 9.1 0.0002 20.8 6.3 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Thiolase_N PF00108.18 EKG10387.1 - 0.0019 17.2 0.1 0.0028 16.6 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EKG10387.1 - 0.076 12.6 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_12 PF08242.7 EKG10388.1 - 1.1e-10 41.8 0.0 2.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10388.1 - 3.4e-07 30.8 0.0 7.6e-07 29.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10388.1 - 0.00047 19.7 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG10388.1 - 0.0014 18.9 0.0 0.0053 17.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG10388.1 - 0.0084 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKG10388.1 - 0.017 14.6 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.12 EKG10388.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EKG10388.1 - 0.027 13.5 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EKG10388.1 - 0.051 13.0 0.1 0.49 9.8 0.0 2.4 1 1 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 EKG10388.1 - 0.06 13.3 0.1 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain KR PF08659.5 EKG10389.1 - 2e-19 69.9 0.2 4.6e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKG10389.1 - 3.7e-13 49.7 1.2 7.4e-13 48.7 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EKG10389.1 - 2.9e-08 33.8 0.0 7.7e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EKG10389.1 - 0.00014 21.4 0.0 0.00039 19.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thioesterase PF00975.15 EKG10390.1 - 0.016 15.4 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain AMP-binding PF00501.23 EKG10391.1 - 1.6e-68 231.0 0.0 2.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG10391.1 - 2.6e-14 53.9 0.0 7.2e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 EKG10392.1 - 5e-12 45.0 0.0 5.4e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 EKG10392.1 - 0.019 14.9 0.1 0.81 9.6 0.1 2.4 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal ketoacyl-synt PF00109.21 EKG10393.1 - 6.3e-72 242.1 0.1 1.6e-71 240.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG10393.1 - 5.8e-56 189.0 2.1 5.8e-56 189.0 1.4 2.9 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 EKG10393.1 - 1e-55 189.3 0.4 7.6e-54 183.1 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain PS-DH PF14765.1 EKG10393.1 - 3.4e-46 157.7 0.2 6.1e-46 156.9 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EKG10393.1 - 3.8e-43 147.2 0.8 3.8e-43 147.2 0.5 3.6 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG10393.1 - 3.7e-38 130.0 0.1 9.2e-38 128.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EKG10393.1 - 2.9e-12 46.2 0.3 3.7e-10 39.4 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG10393.1 - 2.7e-07 30.3 0.0 6.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 EKG10393.1 - 0.00068 18.4 0.0 0.0015 17.3 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.5 EKG10393.1 - 0.0023 17.5 0.4 0.0091 15.6 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.1 EKG10393.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_1 PF00175.16 EKG10394.1 - 1.3e-26 93.3 0.0 1.9e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EKG10394.1 - 4.8e-25 87.5 0.0 7.8e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EKG10394.1 - 3.2e-05 23.8 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain p450 PF00067.17 EKG10395.1 - 1.3e-07 30.5 0.0 4.2e-07 28.8 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 FSH1 PF03959.8 EKG10396.1 - 1.6e-26 93.0 0.0 8.4e-26 90.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EKG10396.1 - 2.1e-11 44.1 1.3 3.2e-11 43.5 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family TLP-20 PF06088.6 EKG10396.1 - 0.27 10.9 0.5 0.38 10.4 0.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DAG1 PF05454.6 EKG10398.1 - 0.00064 18.9 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Zn_clus PF00172.13 EKG10398.1 - 0.0044 16.8 14.6 0.0044 16.8 10.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EKG10398.1 - 0.11 10.7 3.1 0.18 10.0 2.1 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3446 PF11928.3 EKG10398.1 - 0.68 10.1 24.5 1.6 8.9 6.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) MBOAT_2 PF13813.1 EKG10399.1 - 3.5e-20 71.8 0.5 1.3e-19 70.0 0.4 2.0 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family MFS_1 PF07690.11 EKG10400.1 - 5.3e-32 110.8 51.3 2.5e-29 102.1 35.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG10400.1 - 1.8e-07 30.1 13.4 1.8e-07 30.1 9.3 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter p450 PF00067.17 EKG10401.1 - 5.7e-06 25.1 0.0 6.8e-06 24.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.15 EKG10404.1 - 6.8e-21 74.4 0.0 8.7e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EKG10404.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EKG10405.1 - 2.3e-39 135.1 0.0 2.8e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG10406.1 - 1.1e-15 57.9 0.5 1.3e-15 57.7 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10406.1 - 5.9e-09 36.0 0.0 6.7e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG10406.1 - 4.7e-05 23.4 0.8 6.7e-05 22.9 0.6 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG10406.1 - 9.5e-05 22.1 0.1 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EKG10406.1 - 0.001 19.1 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EKG10406.1 - 0.0033 16.9 0.1 0.0045 16.4 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG10406.1 - 0.0042 16.8 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 EKG10406.1 - 0.0053 17.1 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EKG10406.1 - 0.055 12.4 0.1 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EKG10406.1 - 0.073 12.9 0.0 0.092 12.5 0.0 1.3 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Psu PF07455.6 EKG10406.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) Glyco_trans_4_4 PF13579.1 EKG10406.1 - 0.082 13.0 0.5 0.1 12.7 0.4 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain GMC_oxred_N PF00732.14 EKG10408.1 - 8.4e-38 130.2 0.0 1.1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.11 EKG10409.1 - 6.8e-30 103.9 77.4 7.8e-20 70.8 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG10409.1 - 1.5e-07 30.2 16.6 1.5e-07 30.2 11.5 2.9 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 EKG10409.1 - 2.5e-07 29.6 17.6 2.5e-07 29.6 12.2 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EKG10409.1 - 0.017 14.9 3.7 0.017 14.9 2.6 3.6 4 0 0 4 4 4 0 MFS_1 like family MBOAT_2 PF13813.1 EKG10411.1 - 1.9e-16 59.9 2.6 4.1e-16 58.8 1.8 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family NAD_binding_4 PF07993.7 EKG10412.1 - 3e-30 104.9 0.0 5.1e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EKG10412.1 - 4.1e-08 32.0 0.0 9.1e-08 30.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EKG10412.1 - 2.8e-05 24.2 0.0 7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EKG10412.1 - 3.2e-05 23.4 0.0 9.8e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG10412.1 - 0.018 13.9 0.0 1 8.2 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain ketoacyl-synt PF00109.21 EKG10413.1 - 6e-75 251.9 3.2 6e-75 251.9 2.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG10413.1 - 2.8e-39 133.6 2.1 8.2e-39 132.1 1.5 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EKG10413.1 - 3.6e-19 69.2 2.1 3.6e-19 69.2 1.4 2.0 3 0 0 3 3 2 1 Acyl transferase domain PP-binding PF00550.20 EKG10413.1 - 1.2e-18 67.1 8.2 9.2e-11 41.8 0.4 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EKG10413.1 - 4.6e-16 59.1 0.0 2.1e-15 56.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_3 PF07859.8 EKG10413.1 - 3.6e-12 46.2 0.6 2.4e-10 40.3 0.1 2.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 EKG10413.1 - 5.4e-12 45.7 0.0 2.6e-11 43.5 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EKG10413.1 - 2.6e-11 43.4 2.0 6.9e-09 35.6 0.0 3.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 EKG10413.1 - 4.9e-08 32.7 0.0 9.3e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10413.1 - 1.4e-07 32.0 0.0 1.4e-06 28.8 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG10413.1 - 3.9e-07 30.1 4.7 2.5e-06 27.4 0.0 3.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10413.1 - 5.4e-07 30.0 0.0 2.5e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.16 EKG10413.1 - 1.6e-06 27.4 0.0 0.00059 19.1 0.0 2.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Methyltransf_25 PF13649.1 EKG10413.1 - 1.3e-05 25.5 0.0 4e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EKG10413.1 - 0.00037 19.5 0.2 0.00073 18.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EKG10413.1 - 0.00072 19.0 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EKG10413.1 - 0.0085 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Abhydrolase_2 PF02230.11 EKG10413.1 - 0.013 14.9 0.0 3.9 6.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EKG10413.1 - 0.023 14.1 0.0 0.15 11.4 0.0 2.3 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_28 PF02636.12 EKG10413.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EKG10413.1 - 0.08 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 EKG10413.1 - 0.12 11.7 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase COesterase PF00135.23 EKG10413.1 - 1.9 7.1 0.0 2.9 6.4 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family DUF1033 PF06279.6 EKG10413.1 - 2.6 7.8 0.4 4.8 7.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) AMP-binding PF00501.23 EKG10414.1 - 0 1074.4 0.0 8.9e-82 274.6 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EKG10414.1 - 1.5e-140 467.2 0.3 7.3e-35 120.2 0.3 5.4 4 2 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EKG10414.1 - 3.6e-40 136.0 1.5 1.3e-08 35.0 0.0 5.9 5 0 0 5 5 5 4 Phosphopantetheine attachment site GH3 PF03321.8 EKG10414.1 - 0.0066 15.0 0.2 11 4.3 0.0 4.1 4 0 0 4 4 4 1 GH3 auxin-responsive promoter Transferase PF02458.10 EKG10414.1 - 0.065 11.6 0.0 7.8 4.8 0.0 2.3 2 0 0 2 2 2 0 Transferase family Peptidase_M16_C PF05193.16 EKG10414.1 - 0.31 10.6 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Peptidase M16 inactive domain DUF1347 PF07079.6 EKG10414.1 - 0.35 9.0 0.1 0.58 8.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) AATase PF07247.7 EKG10414.1 - 1.6 7.1 0.1 32 2.8 0.0 2.6 3 0 0 3 3 3 0 Alcohol acetyltransferase MA-Mit PF09245.5 EKG10414.1 - 3.8 6.7 0.1 28 3.8 0.0 2.4 2 0 0 2 2 2 0 Mycoplasma arthritidis-derived mitogen Beta-lactamase PF00144.19 EKG10415.1 - 3.4e-40 138.0 0.1 4.6e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Ank_2 PF12796.2 EKG10416.1 - 2.1e-21 76.0 2.1 8.2e-21 74.1 1.4 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKG10416.1 - 4.8e-20 70.2 8.4 1.1e-09 37.5 0.2 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EKG10416.1 - 1.4e-16 60.5 1.0 7.8e-08 32.6 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG10416.1 - 1.6e-16 59.9 10.1 8.1e-10 38.6 0.6 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG10416.1 - 5.6e-14 50.8 2.1 0.00012 22.0 0.2 3.3 3 1 0 3 3 3 3 Ankyrin repeat Amidinotransf PF02274.12 EKG10417.1 - 0.082 11.9 0.0 1.1 8.2 0.0 2.2 2 1 0 2 2 2 0 Amidinotransferase ABC_tran PF00005.22 EKG10418.1 - 4.4e-41 140.3 0.0 2.1e-23 83.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKG10418.1 - 1.1e-27 97.2 14.0 1.2e-19 70.8 2.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EKG10418.1 - 1.4e-12 47.3 0.6 0.00086 18.5 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EKG10418.1 - 3.8e-11 43.3 0.6 1.7e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EKG10418.1 - 5.3e-11 43.0 0.9 0.13 12.2 0.2 4.2 3 1 1 4 4 4 3 AAA domain AAA_29 PF13555.1 EKG10418.1 - 5.1e-08 32.3 0.4 0.0018 17.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EKG10418.1 - 1.3e-06 28.3 0.1 0.034 13.9 0.2 2.3 2 0 0 2 2 2 2 Dynamin family AAA_25 PF13481.1 EKG10418.1 - 7.8e-06 25.4 0.1 0.15 11.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 EKG10418.1 - 1.1e-05 24.7 0.1 0.0022 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG10418.1 - 1.5e-05 25.8 0.0 0.0038 18.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKG10418.1 - 1.5e-05 24.9 0.0 0.011 15.7 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EKG10418.1 - 1.8e-05 25.1 0.0 0.033 14.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EKG10418.1 - 2.6e-05 24.6 1.3 0.02 15.3 0.1 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_22 PF13401.1 EKG10418.1 - 0.0001 22.4 0.0 0.096 12.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG10418.1 - 0.00017 21.8 0.0 0.052 13.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EKG10418.1 - 0.00018 21.0 2.4 0.012 15.0 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EKG10418.1 - 0.00024 20.9 0.0 0.79 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EKG10418.1 - 0.00031 20.4 0.3 0.64 9.7 0.0 2.9 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EKG10418.1 - 0.00065 18.6 0.1 0.99 8.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein ABC_ATPase PF09818.4 EKG10418.1 - 0.0015 17.2 2.5 0.22 10.0 0.1 3.1 4 0 0 4 4 4 1 Predicted ATPase of the ABC class Arch_ATPase PF01637.13 EKG10418.1 - 0.0054 16.4 0.1 5.4 6.6 0.0 3.0 3 1 0 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 EKG10418.1 - 0.0055 16.1 0.6 0.17 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 EKG10418.1 - 0.0061 15.6 0.1 2.9 6.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin PduV-EutP PF10662.4 EKG10418.1 - 0.034 13.6 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 EKG10418.1 - 0.036 13.6 0.5 1.4 8.6 0.0 2.7 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EKG10418.1 - 0.042 13.2 1.6 5.3 6.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EKG10418.1 - 0.05 13.5 0.4 4.3 7.3 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRPRB PF09439.5 EKG10418.1 - 0.068 12.3 0.1 0.65 9.1 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKG10418.1 - 0.12 11.8 0.2 6.5 6.1 0.0 3.0 4 0 0 4 4 3 0 Elongation factor Tu GTP binding domain AAA PF00004.24 EKG10418.1 - 0.15 12.2 0.1 21 5.3 0.0 3.3 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IIGP PF05049.8 EKG10418.1 - 0.17 10.6 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MFS_1 PF07690.11 EKG10419.1 - 1e-16 60.6 29.0 1e-16 60.6 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG10419.1 - 6.6e-06 24.9 0.5 6.6e-06 24.9 0.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Peptidase_M20 PF01546.23 EKG10420.1 - 3e-26 92.0 0.6 3.7e-26 91.7 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EKG10420.1 - 4.7e-06 26.4 0.0 2.1e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 EKG10420.1 - 2.5e-05 23.9 0.1 8.4e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF3322 PF11795.3 EKG10420.1 - 0.034 13.8 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) IDO PF01231.13 EKG10421.1 - 8.6e-137 456.0 0.0 9.8e-137 455.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Myelin_MBP PF01669.12 EKG10421.1 - 0.094 12.9 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Myelin basic protein AMP-binding PF00501.23 EKG10422.1 - 2.1e-229 760.9 0.0 6.2e-76 255.4 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EKG10422.1 - 9.8e-147 487.6 0.0 1.1e-40 139.3 0.0 5.6 4 2 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EKG10422.1 - 4.2e-48 161.4 3.2 3.1e-11 43.3 0.0 5.1 5 0 0 5 5 5 4 Phosphopantetheine attachment site Transferase PF02458.10 EKG10422.1 - 0.018 13.4 0.0 0.98 7.7 0.0 2.2 2 0 0 2 2 2 0 Transferase family Pox_A8 PF04745.7 EKG10422.1 - 1.2 8.0 0.3 3.4 6.5 0.0 1.8 2 0 0 2 2 2 0 VITF-3 subunit protein DUF3763 PF12592.3 EKG10424.1 - 0.028 14.0 0.5 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3763) UbiA PF01040.13 EKG10426.1 - 3.4e-18 65.7 13.0 4.4e-18 65.4 9.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family 7TM_GPCR_Srh PF10318.4 EKG10427.1 - 0.092 11.5 1.7 0.13 11.0 0.6 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srh Amidohydro_2 PF04909.9 EKG10428.1 - 7e-33 114.3 5.1 8.6e-33 114.0 3.5 1.1 1 0 0 1 1 1 1 Amidohydrolase Zn_clus PF00172.13 EKG10429.1 - 3.6e-07 29.9 13.5 3.6e-07 29.9 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF685 PF05085.7 EKG10429.1 - 0.17 10.9 0.1 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF685) Fungal_trans PF04082.13 EKG10430.1 - 8.9e-15 54.2 0.0 6.5e-14 51.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG10430.1 - 1.1e-10 41.2 11.1 2.1e-10 40.3 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EKG10431.1 - 4.7e-62 210.0 0.0 6.1e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.1 EKG10432.1 - 3.3e-19 68.7 1.5 8.3e-19 67.4 1.0 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.20 EKG10433.1 - 2.4e-14 53.5 2.3 3.8e-14 52.9 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10433.1 - 5.4e-09 35.9 1.1 7.9e-09 35.4 0.7 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG10433.1 - 2.2e-06 27.6 0.0 3.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG10433.1 - 3.5e-06 27.1 0.5 6.1e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1152 PF06626.7 EKG10433.1 - 0.009 15.1 0.4 0.016 14.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1152) Polysacc_synt_2 PF02719.10 EKG10433.1 - 0.014 14.2 0.1 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EKG10433.1 - 0.058 12.4 0.1 0.12 11.4 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Cupin_2 PF07883.6 EKG10434.1 - 3.6e-08 32.7 0.8 6.1e-08 32.0 0.5 1.3 1 0 0 1 1 1 1 Cupin domain MerC PF03203.9 EKG10435.1 - 2.6 8.4 10.7 0.56 10.5 5.0 1.7 2 0 0 2 2 2 0 MerC mercury resistance protein Acyl_transf_1 PF00698.16 EKG10437.1 - 6.1e-41 140.7 0.0 8.6e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EKG10437.1 - 3.7e-07 29.6 0.3 7.3e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase p450 PF00067.17 EKG10438.1 - 1.8e-73 247.6 0.0 1.2e-72 244.9 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 EKG10439.1 - 1.6e-54 184.8 0.0 2.3e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG10439.1 - 9.2e-24 83.8 0.0 9.4e-23 80.5 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EKG10439.1 - 5.9e-21 74.3 0.0 8.6e-21 73.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG10439.1 - 1.5e-18 66.6 0.0 9.3e-18 64.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EKG10439.1 - 1e-17 63.9 0.0 1.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain UDPGT PF00201.13 EKG10439.1 - 2e-10 39.8 0.0 9.2e-10 37.6 0.0 1.8 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase NAD_binding_10 PF13460.1 EKG10439.1 - 5.9e-07 29.6 0.1 4.5e-06 26.7 0.0 2.4 2 1 0 2 2 2 1 NADH(P)-binding Glyco_tran_28_C PF04101.11 EKG10439.1 - 0.00034 20.3 0.0 0.00068 19.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.15 EKG10439.1 - 0.00074 19.2 0.1 0.0044 16.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.1 EKG10439.1 - 0.0078 15.4 0.0 0.041 13.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 1 adh_short PF00106.20 EKG10439.1 - 0.014 15.2 0.1 0.078 12.8 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EKG10439.1 - 0.019 14.6 0.0 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 KR domain Metallopep PF12044.3 EKG10440.1 - 6.8e-169 561.7 0.0 8.2e-169 561.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EKG10440.1 - 3.7e-05 23.6 0.0 0.00011 22.0 0.0 1.8 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EKG10440.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EKG10440.1 - 0.08 12.9 0.2 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Whi5 PF08528.6 EKG10441.1 - 2.5e-10 39.6 0.0 5.9e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 Whi5 like ABA_WDS PF02496.11 EKG10442.1 - 0.033 14.3 0.3 0.06 13.5 0.2 1.3 1 0 0 1 1 1 0 ABA/WDS induced protein Amidoligase_2 PF12224.3 EKG10443.1 - 1.7e-17 63.8 0.1 2.4e-09 37.1 0.0 2.9 2 1 0 2 2 2 2 Putative amidoligase enzyme Neuromodulin_N PF10580.4 EKG10443.1 - 0.11 12.1 0.2 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Gap junction protein N-terminal region Glyco_hydro_47 PF01532.15 EKG10444.1 - 1.6e-166 554.4 0.1 1.9e-166 554.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Med14 PF08638.6 EKG10445.1 - 1e-62 210.8 0.0 2.4e-62 209.6 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 ATG22 PF11700.3 EKG10446.1 - 6.7e-206 684.3 5.6 7.7e-206 684.1 3.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EKG10446.1 - 8.6e-06 24.6 42.7 1.7e-05 23.6 11.2 3.3 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EKG10446.1 - 0.00014 20.3 6.9 0.00014 20.3 4.8 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein Thioredoxin PF00085.15 EKG10447.1 - 2.1e-64 213.7 9.4 3.1e-32 110.3 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EKG10447.1 - 3.7e-57 193.1 7.1 5.1e-40 137.2 0.8 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKG10447.1 - 9.2e-12 44.9 0.9 0.0014 18.6 0.0 4.5 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EKG10447.1 - 6e-10 39.0 0.2 0.00046 20.1 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 EKG10447.1 - 1e-09 37.6 1.3 2.4e-09 36.4 0.9 1.7 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 EKG10447.1 - 2.6e-09 37.2 5.7 0.0002 21.5 0.1 4.5 3 3 1 4 4 4 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EKG10447.1 - 2.2e-08 33.8 2.1 0.00039 20.0 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EKG10447.1 - 1e-06 28.3 2.0 0.036 13.6 0.0 2.9 3 0 0 3 3 3 2 Redoxin DSBA PF01323.15 EKG10447.1 - 0.0037 16.8 0.2 5 6.6 0.0 3.5 3 1 1 4 4 4 2 DSBA-like thioredoxin domain NMD3 PF04981.8 EKG10447.1 - 0.0046 16.0 0.5 1.8 7.6 0.0 2.5 2 0 0 2 2 2 2 NMD3 family Thioredoxin_3 PF13192.1 EKG10447.1 - 0.0099 15.6 0.3 0.087 12.6 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin domain YtxH PF12732.2 EKG10447.1 - 9.3 6.6 13.6 1.6 9.1 2.8 4.1 3 2 0 3 3 3 0 YtxH-like protein Gpi1 PF05024.10 EKG10448.1 - 3.2e-64 216.1 8.5 5.7e-64 215.2 5.9 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) zf-CCCH PF00642.19 EKG10449.1 - 3.9e-08 32.7 3.0 3.9e-08 32.7 2.1 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EKG10449.1 - 0.028 14.4 6.5 0.081 12.9 4.5 1.9 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Clp1 PF06807.9 EKG10450.1 - 8e-09 35.5 0.0 2e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EKG10450.1 - 2.7e-06 27.1 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EKG10450.1 - 0.011 16.2 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 EKG10450.1 - 0.025 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EKG10450.1 - 0.037 13.9 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EKG10450.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EKG10450.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family RNA_polI_A34 PF08208.6 EKG10451.1 - 5.6e-27 94.7 21.6 5.6e-27 94.7 14.9 3.3 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 BSP_II PF05432.6 EKG10451.1 - 0.0057 15.9 38.1 0.14 11.3 18.1 2.2 2 0 0 2 2 2 2 Bone sialoprotein II (BSP-II) Microtub_assoc PF07989.6 EKG10452.1 - 1.2e-22 79.5 11.2 1.2e-22 79.5 7.8 9.9 8 2 3 11 11 11 1 Microtubule associated Mto2_bdg PF12808.2 EKG10452.1 - 2.4e-17 62.7 19.3 2.4e-17 62.7 13.4 12.4 11 3 1 12 12 12 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Tropomyosin_1 PF12718.2 EKG10452.1 - 2.3e-05 24.2 26.9 2.3e-05 24.2 18.6 9.3 6 2 2 10 10 10 1 Tropomyosin like Reo_sigmaC PF04582.7 EKG10452.1 - 3.9e-05 23.0 1.5 3.9e-05 23.0 1.0 6.0 4 1 2 6 6 6 3 Reovirus sigma C capsid protein ATG16 PF08614.6 EKG10452.1 - 0.00052 19.8 17.2 0.00052 19.8 11.9 11.7 5 3 4 10 10 10 5 Autophagy protein 16 (ATG16) HATPase_c_3 PF13589.1 EKG10453.1 - 3.9e-06 26.5 0.0 4.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKG10453.1 - 0.00029 20.5 0.0 0.00047 19.8 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carb_anhydrase PF00194.16 EKG10454.1 - 1.3e-21 76.7 0.0 2.4e-21 75.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GSu_C4xC__C2xCH PF09698.5 EKG10455.1 - 0.054 13.6 0.1 0.088 12.9 0.1 1.3 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Pkinase PF00069.20 EKG10456.1 - 4.2e-68 229.3 0.0 6.2e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG10456.1 - 1.8e-47 161.6 0.0 2.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG10456.1 - 2.8e-09 36.3 0.0 9.2e-08 31.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EKG10456.1 - 0.0051 15.9 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mon1 PF03164.9 EKG10457.1 - 7.5e-107 357.4 0.0 6e-93 311.6 0.0 2.1 1 1 1 2 2 2 2 Trafficking protein Mon1 IncA PF04156.9 EKG10460.1 - 0.033 13.7 1.3 0.056 13.0 0.9 1.3 1 0 0 1 1 1 0 IncA protein DUF2130 PF09903.4 EKG10460.1 - 0.038 12.7 1.4 0.095 11.4 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Mer2 PF09074.5 EKG10460.1 - 0.053 13.4 0.6 0.11 12.4 0.4 1.5 1 0 0 1 1 1 0 Mer2 Peroxin-3 PF04882.7 EKG10460.1 - 0.053 12.2 0.3 0.078 11.6 0.2 1.1 1 0 0 1 1 1 0 Peroxin-3 PAS_9 PF13426.1 EKG10461.1 - 3.3e-30 104.5 0.0 4e-17 62.4 0.0 3.6 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 EKG10461.1 - 1.2e-17 63.6 0.0 1.9e-08 34.0 0.0 3.8 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.6 EKG10461.1 - 3.3e-16 59.1 0.0 7.1e-10 38.8 0.0 3.9 4 0 0 4 4 4 3 PAS fold GATA PF00320.22 EKG10461.1 - 1.7e-14 52.8 8.2 4e-14 51.6 5.7 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS_11 PF14598.1 EKG10461.1 - 9.1e-12 44.9 0.0 6.2e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EKG10461.1 - 3.5e-07 30.2 0.0 0.17 11.9 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_10 PF13596.1 EKG10461.1 - 0.013 15.7 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 0 PAS domain PAS_8 PF13188.1 EKG10461.1 - 0.013 15.3 0.0 0.69 9.8 0.0 2.5 2 0 0 2 2 2 0 PAS domain Cytochrom_c3_2 PF14537.1 EKG10461.1 - 0.21 11.9 2.3 0.57 10.5 1.6 1.7 1 0 0 1 1 1 0 Cytochrome c3 Ribosomal_S2 PF00318.15 EKG10462.1 - 8.7e-48 162.3 0.0 1.6e-47 161.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S2 COPI_assoc PF08507.5 EKG10462.1 - 0.061 12.9 0.0 0.097 12.3 0.0 1.2 1 0 0 1 1 1 0 COPI associated protein Mito_carr PF00153.22 EKG10463.1 - 1.9e-22 78.7 0.1 2.1e-22 78.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Ribosomal_L20 PF00453.13 EKG10464.1 - 0.045 13.6 1.3 0.077 12.9 0.9 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 eIF2A PF08662.6 EKG10466.1 - 5.2e-81 271.0 0.1 8.6e-80 267.0 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EKG10466.1 - 1.3e-05 24.9 0.0 0.39 10.6 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat CDV3 PF15359.1 EKG10466.1 - 0.0029 17.6 0.3 0.0029 17.6 0.2 2.9 4 0 0 4 4 4 1 Carnitine deficiency-associated protein 3 PD40 PF07676.7 EKG10466.1 - 0.019 14.6 1.7 3.1 7.5 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Apc1 PF12859.2 EKG10468.1 - 1.1e-25 89.8 0.2 1.1e-25 89.8 0.1 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EKG10468.1 - 4.2e-06 26.7 2.9 0.14 12.4 0.4 3.8 3 0 0 3 3 3 2 Proteasome/cyclosome repeat FAD_binding_3 PF01494.14 EKG10475.1 - 1.1e-23 83.9 0.0 3.3e-16 59.2 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EKG10475.1 - 0.0005 19.8 0.1 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EKG10475.1 - 0.0028 17.6 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TetR_C_6 PF13977.1 EKG10475.1 - 0.56 10.2 6.3 0.62 10.1 0.3 2.8 3 0 0 3 3 3 0 Bacterial transcriptional repressor NAD_binding_11 PF14833.1 EKG10476.1 - 1.1e-23 83.5 0.0 1.3e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase HgmA PF04209.8 EKG10477.1 - 8.3e-154 512.0 0.3 9.6e-154 511.8 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AraC_binding_2 PF14525.1 EKG10477.1 - 0.071 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 AraC-binding-like domain adh_short PF00106.20 EKG10478.1 - 1.5e-17 63.9 0.0 2.5e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10478.1 - 2.9e-06 27.0 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG10478.1 - 5.1e-05 23.1 0.0 6.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG10478.1 - 0.019 14.3 0.1 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG10478.1 - 0.032 14.0 0.2 0.075 12.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EKG10478.1 - 0.033 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EKG10478.1 - 0.045 13.3 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cullin PF00888.17 EKG10479.1 - 4e-42 144.5 0.5 1.1e-41 143.1 0.3 1.5 1 1 0 1 1 1 1 Cullin family APC2 PF08672.6 EKG10479.1 - 4.3e-09 36.4 0.0 1.2e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 DUF3753 PF12575.3 EKG10479.1 - 0.2 11.4 0.4 13 5.6 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3753) LRR_4 PF12799.2 EKG10480.1 - 0.22 11.1 3.3 4.1 7.1 1.2 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) SMC_N PF02463.14 EKG10481.1 - 3.7e-25 88.4 0.0 7.8e-25 87.4 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKG10481.1 - 1.6e-07 31.8 36.9 1.6e-07 31.8 25.6 5.9 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EKG10481.1 - 3.8e-07 30.3 0.1 5.4e-05 23.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.1 EKG10481.1 - 1.3e-06 26.5 40.5 1.3e-06 26.5 28.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EKG10481.1 - 0.00016 20.9 2.0 0.0002 20.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EKG10481.1 - 0.0012 18.6 0.0 0.0041 16.9 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EKG10481.1 - 0.0013 18.1 0.1 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Sec8_exocyst PF04048.9 EKG10481.1 - 0.053 13.1 24.4 0.17 11.4 0.1 5.8 4 3 2 6 6 6 0 Sec8 exocyst complex component specific domain PRK PF00485.13 EKG10481.1 - 0.24 10.9 9.6 0.31 10.5 0.6 3.5 3 1 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EKG10481.1 - 0.4 10.9 0.0 0.4 10.9 0.0 5.8 3 2 1 4 4 4 0 ABC transporter CLP_protease PF00574.18 EKG10482.1 - 8.1e-76 253.7 0.0 1e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.11 EKG10482.1 - 0.037 12.8 0.2 0.098 11.4 0.0 1.7 2 0 0 2 2 2 0 Serine dehydrogenase proteinase RdRP PF05183.7 EKG10484.1 - 1.5e-174 581.9 0.0 2.1e-174 581.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 EKG10484.1 - 0.0012 18.7 0.1 0.031 14.2 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG10484.1 - 0.0012 18.4 0.1 0.0065 16.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2b PF00587.20 EKG10485.1 - 2.2e-45 154.3 0.3 4.2e-45 153.4 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKG10485.1 - 1.1e-16 60.5 0.6 2.5e-16 59.4 0.4 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EKG10485.1 - 2.2e-13 49.8 0.2 5.5e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EKG10485.1 - 3.9e-13 49.0 0.0 1e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 EKG10486.1 - 9.8e-39 132.2 0.1 1.1e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 EKG10487.1 - 1.5e-13 50.8 2.2 2.7e-13 50.0 1.6 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PqiA PF04403.8 EKG10487.1 - 0.073 12.6 1.1 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Paraquat-inducible protein A Fungal_trans PF04082.13 EKG10488.1 - 2e-18 66.1 0.9 3.3e-18 65.4 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EKG10488.1 - 0.00034 20.7 17.8 0.0064 16.7 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG10488.1 - 0.0011 19.1 16.3 0.038 14.3 2.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG10488.1 - 0.0037 17.4 8.1 0.0037 17.4 5.6 3.2 3 0 0 3 3 3 2 Zinc-finger double domain COesterase PF00135.23 EKG10489.1 - 0.0064 15.2 0.0 0.0064 15.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Glyco_hydro_28 PF00295.12 EKG10491.1 - 7.8e-98 327.4 16.9 9e-98 327.2 11.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EKG10491.1 - 2.3e-05 24.2 42.6 3e-05 23.8 15.7 3.3 2 1 1 3 3 3 2 Right handed beta helix region DUF2111 PF09884.4 EKG10491.1 - 0.013 15.3 0.1 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) NosD PF05048.8 EKG10491.1 - 0.036 13.2 19.5 0.97 8.5 13.5 2.3 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DUF1178 PF06676.6 EKG10492.1 - 0.1 12.8 2.6 0.6 10.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Prok-RING_1 PF14446.1 EKG10492.1 - 0.14 11.9 3.4 0.26 11.0 2.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 AMP-binding PF00501.23 EKG10493.1 - 2e-14 52.8 0.0 7e-14 51.0 0.0 1.8 3 0 0 3 3 3 1 AMP-binding enzyme PP-binding PF00550.20 EKG10493.1 - 1.2e-07 31.8 0.4 2.4e-07 30.8 0.3 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site DIT1_PvcA PF05141.7 EKG10494.1 - 7.3e-70 235.4 0.0 8.2e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DIT1_PvcA PF05141.7 EKG10495.1 - 3.9e-43 147.7 0.0 2.5e-24 86.0 0.0 2.0 2 0 0 2 2 2 2 Pyoverdine/dityrosine biosynthesis protein FAD_binding_3 PF01494.14 EKG10497.1 - 7e-10 38.4 0.0 8.8e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EKG10497.1 - 2.8e-05 23.9 0.5 0.0021 17.8 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EKG10497.1 - 3.9e-05 23.5 1.2 0.00019 21.3 0.1 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG10497.1 - 0.00013 21.0 3.9 0.003 16.5 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG10497.1 - 0.011 14.6 0.7 0.48 9.2 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EKG10497.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EKG10497.1 - 0.34 9.4 1.7 0.84 8.1 0.2 1.9 1 1 1 2 2 2 0 Tryptophan halogenase Peptidase_C14 PF00656.17 EKG10498.1 - 1.9e-72 243.9 0.0 2.4e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Caspase domain SHMT PF00464.14 EKG10499.1 - 1.6e-204 678.7 0.0 1.8e-204 678.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EKG10499.1 - 2e-07 30.2 0.0 6e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EKG10499.1 - 9.9e-05 21.2 0.0 0.00014 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EKG10499.1 - 0.00048 19.3 0.0 0.0014 17.8 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase Glyco_hydro_43 PF04616.9 EKG10500.1 - 2.7e-24 85.7 5.2 3.5e-23 82.0 2.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 DUF2051 PF09738.4 EKG10501.1 - 0.13 11.5 2.6 0.19 11.0 1.8 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) OB_NTP_bind PF07717.11 EKG10503.1 - 6.2e-20 71.1 0.0 1.3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKG10503.1 - 6.5e-19 67.8 0.1 2e-18 66.2 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKG10503.1 - 2.9e-13 49.4 0.0 7.2e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG10503.1 - 5.9e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKG10503.1 - 0.0016 18.5 0.0 0.0049 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EKG10503.1 - 0.011 15.2 0.0 0.026 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EKG10503.1 - 0.15 10.6 1.2 0.42 9.2 0.6 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Transaldolase PF00923.14 EKG10504.1 - 1.3e-71 241.1 0.0 1.5e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Zn_clus PF00172.13 EKG10505.1 - 5.5e-07 29.3 7.5 8.6e-07 28.7 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EKG10506.1 - 5.5e-10 38.5 0.9 5.5e-10 38.5 0.7 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain HET PF06985.6 EKG10507.1 - 6.8e-19 68.3 0.0 1.4e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EKG10509.1 - 3.6e-05 23.9 0.0 8.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAR9 PF08580.5 EKG10509.1 - 0.17 10.1 3.0 0.23 9.7 2.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ank_2 PF12796.2 EKG10510.1 - 3.1e-37 126.7 5.4 4.9e-19 68.4 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG10510.1 - 1.3e-36 122.5 14.6 2.8e-07 30.0 0.0 6.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EKG10510.1 - 6.2e-24 83.9 2.6 3.2e-07 30.6 0.1 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG10510.1 - 3.6e-23 79.3 8.6 8.3e-05 22.4 0.1 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EKG10510.1 - 6.5e-23 80.2 7.7 1.4e-07 31.4 0.2 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EKG10510.1 - 0.00058 19.4 0.0 0.0031 17.0 0.0 2.1 2 1 0 2 2 2 1 Shigella flexneri OspC protein HET PF06985.6 EKG10511.1 - 8.2e-35 119.9 0.0 1.4e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spherulin4 PF12138.3 EKG10514.1 - 6.6e-49 166.6 0.4 7.5e-49 166.4 0.3 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Cyt-b5 PF00173.23 EKG10516.1 - 8.1e-16 57.5 0.0 1.9e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EKG10516.1 - 8e-08 32.0 2.5 1.3e-07 31.3 1.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF1244 PF06844.6 EKG10516.1 - 0.067 13.0 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) Arylsulfotran_2 PF14269.1 EKG10517.1 - 1.4e-60 204.9 0.3 2.2e-60 204.3 0.2 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EKG10517.1 - 5.8e-22 77.8 0.0 1e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Abhydrolase_6 PF12697.2 EKG10522.1 - 2e-09 37.7 0.3 7.9e-09 35.7 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG10522.1 - 4.6e-07 29.6 0.0 1.6e-06 27.8 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG10522.1 - 6.6e-07 29.1 0.0 2e-06 27.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG10522.1 - 0.025 14.4 0.0 0.091 12.6 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase ABM PF03992.11 EKG10523.1 - 7.1e-16 58.0 0.0 9.4e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aa_trans PF01490.13 EKG10524.1 - 3.7e-26 91.5 29.9 4.3e-26 91.3 20.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF368 PF04018.8 EKG10524.1 - 0.0019 17.4 7.7 0.0019 17.4 5.4 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF368) AA_permease_2 PF13520.1 EKG10524.1 - 0.0061 15.1 51.2 0.0091 14.5 22.0 2.8 1 1 1 2 2 2 1 Amino acid permease SdpI PF13630.1 EKG10524.1 - 0.012 15.2 5.7 0.012 15.2 4.0 4.6 7 0 0 7 7 7 0 SdpI/YhfL protein family HEM4 PF02602.10 EKG10524.1 - 0.067 12.4 0.1 0.1 11.8 0.1 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD SDH_alpha PF03313.10 EKG10524.1 - 0.84 8.6 3.8 1.9 7.4 2.6 1.5 1 0 0 1 1 1 0 Serine dehydratase alpha chain Fungal_trans PF04082.13 EKG10526.1 - 1.5e-28 99.3 0.2 2.6e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG10526.1 - 2.9e-06 27.0 10.9 4.9e-06 26.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTBV_P12 PF06361.6 EKG10526.1 - 0.38 10.9 1.6 0.59 10.3 0.1 2.0 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein Aldo_ket_red PF00248.16 EKG10527.1 - 1.9e-51 174.5 0.0 2.3e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C2H2_4 PF13894.1 EKG10531.1 - 1.6e-05 24.8 11.0 0.16 12.3 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG10531.1 - 0.0026 17.9 12.3 0.2 12.0 0.0 3.7 3 1 0 3 3 3 3 Zinc finger, C2H2 type DUF1421 PF07223.6 EKG10531.1 - 0.0065 16.2 28.2 0.01 15.6 19.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1421) PAT1 PF09770.4 EKG10531.1 - 7.6 4.6 11.3 8.9 4.4 7.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AMP-binding PF00501.23 EKG10532.1 - 9.1e-34 116.5 0.0 1.3e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EKG10532.1 - 1.4e-09 38.0 0.0 2.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site GPI-anchored PF10342.4 EKG10533.1 - 5.2e-20 71.7 0.3 7.2e-20 71.2 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_23 PF13489.1 EKG10536.1 - 1e-18 67.6 0.0 1.5e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10536.1 - 4.3e-15 55.9 0.0 9.7e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10536.1 - 4.5e-11 42.5 0.0 9.7e-10 38.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG10536.1 - 2.2e-10 40.8 0.0 1.7e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10536.1 - 6.8e-09 36.2 0.0 1.3e-07 32.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG10536.1 - 1.3e-07 30.9 0.0 1.5e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EKG10536.1 - 1.9e-07 31.3 0.0 4.1e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG10536.1 - 1.9e-05 24.1 0.0 5.2e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EKG10536.1 - 5e-05 23.3 0.0 0.00024 21.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG10536.1 - 0.0029 16.6 0.1 0.018 14.0 0.0 2.2 3 0 0 3 3 3 1 Putative methyltransferase CMAS PF02353.15 EKG10536.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.11 EKG10536.1 - 0.01 14.2 0.1 0.54 8.5 0.0 2.2 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 EKG10536.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EKG10536.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 EKG10536.1 - 0.034 13.7 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase FtsJ PF01728.14 EKG10536.1 - 0.047 13.6 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Acyl-CoA_dh_2 PF08028.6 EKG10537.1 - 1.9e-16 60.5 0.8 3.4e-16 59.7 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 EKG10537.1 - 4.8e-05 23.4 0.5 0.00026 21.0 0.3 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 EKG10537.1 - 0.0017 18.0 0.1 0.0056 16.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2190) TLD PF07534.11 EKG10538.1 - 3e-28 98.5 0.0 1.2e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 TLD Prefoldin_2 PF01920.15 EKG10539.1 - 3.8e-20 71.6 15.1 3.8e-20 71.6 10.4 2.0 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EKG10539.1 - 0.0036 17.0 6.2 0.0036 17.0 4.3 1.5 2 0 0 2 2 1 1 Prefoldin subunit Spc24 PF08286.6 EKG10539.1 - 0.0091 15.6 4.8 0.0091 15.6 3.3 2.7 2 1 1 3 3 3 1 Spc24 subunit of Ndc80 DUF4349 PF14257.1 EKG10539.1 - 0.013 14.7 2.7 0.028 13.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Spc7 PF08317.6 EKG10539.1 - 0.044 12.4 9.1 0.071 11.7 6.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Med3 PF11593.3 EKG10539.1 - 0.049 12.8 0.7 0.049 12.8 0.5 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GP41 PF00517.12 EKG10539.1 - 0.12 11.9 11.3 0.14 11.6 0.7 2.1 2 0 0 2 2 2 0 Retroviral envelope protein DASH_Dad3 PF08656.5 EKG10539.1 - 0.29 10.8 4.4 3.1 7.5 1.4 2.8 2 1 1 3 3 3 0 DASH complex subunit Dad3 NPV_P10 PF05531.7 EKG10539.1 - 0.36 11.1 12.1 0.64 10.3 2.7 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.6 EKG10539.1 - 0.37 10.6 6.7 8 6.3 0.1 2.3 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Macoilin PF09726.4 EKG10539.1 - 0.41 8.8 7.0 0.48 8.6 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Mnd1 PF03962.10 EKG10539.1 - 0.44 10.1 11.7 0.81 9.3 0.4 2.1 1 1 1 2 2 2 0 Mnd1 family Occludin_ELL PF07303.8 EKG10539.1 - 0.45 11.2 7.0 0.76 10.5 0.9 2.5 2 1 0 2 2 2 0 Occludin homology domain Streptin-Immun PF11083.3 EKG10539.1 - 0.56 10.2 5.1 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein DUF972 PF06156.8 EKG10539.1 - 1 9.7 9.1 0.97 9.8 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EKG10539.1 - 1.1 8.8 21.8 1.1 8.7 2.6 2.2 1 1 1 2 2 2 0 IncA protein Sas10_Utp3 PF04000.10 EKG10539.1 - 1.2 9.4 6.3 0.13 12.5 0.5 2.3 3 0 0 3 3 3 0 Sas10/Utp3/C1D family Retrotrans_gag PF03732.12 EKG10539.1 - 1.6 8.8 7.5 5 7.2 0.9 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein Tropomyosin_1 PF12718.2 EKG10539.1 - 1.6 8.5 17.2 0.57 10.0 4.1 2.4 3 0 0 3 3 2 0 Tropomyosin like Lzipper-MIP1 PF14389.1 EKG10539.1 - 1.8 8.7 13.1 0.34 11.0 2.7 2.9 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Laminin_II PF06009.7 EKG10539.1 - 2 8.1 7.4 2.9 7.6 2.6 2.1 1 1 1 2 2 2 0 Laminin Domain II Spectrin PF00435.16 EKG10539.1 - 2.9 8.2 14.7 0.5 10.6 3.8 2.6 3 0 0 3 3 3 0 Spectrin repeat TPR_MLP1_2 PF07926.7 EKG10539.1 - 3.6 7.3 17.0 4.8 6.9 8.2 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Allexi_40kDa PF05549.6 EKG10539.1 - 4.3 6.5 5.3 5.1 6.3 1.3 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein FemAB PF02388.11 EKG10539.1 - 5.7 5.5 8.2 12 4.3 0.1 2.0 1 1 1 2 2 2 0 FemAB family Latarcin PF10279.4 EKG10539.1 - 5.7 7.1 6.1 2.5 8.3 0.6 2.4 2 1 0 2 2 2 0 Latarcin precursor DUF1664 PF07889.7 EKG10539.1 - 6.5 6.5 6.7 15 5.4 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cast PF10174.4 EKG10539.1 - 8.9 4.2 14.9 1 7.3 4.0 2.1 1 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone AAA PF00004.24 EKG10540.1 - 1.9e-42 144.5 0.0 3.2e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EKG10540.1 - 2e-28 98.0 0.5 6.4e-28 96.4 0.0 2.2 3 0 0 3 3 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EKG10540.1 - 1.6e-22 79.1 2.5 1.6e-22 79.1 1.7 2.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EKG10540.1 - 6.2e-06 27.0 0.1 2.6e-05 25.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EKG10540.1 - 8.5e-06 24.9 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKG10540.1 - 3.9e-05 23.7 0.1 0.005 16.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKG10540.1 - 4.3e-05 23.2 0.0 0.00024 20.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EKG10540.1 - 4.9e-05 22.8 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EKG10540.1 - 5.6e-05 23.0 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKG10540.1 - 6.4e-05 23.0 0.0 0.011 15.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 EKG10540.1 - 0.00013 21.9 0.0 0.0028 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EKG10540.1 - 0.00016 21.5 0.0 0.00034 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EKG10540.1 - 0.00019 20.2 0.0 0.00031 19.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EKG10540.1 - 0.00023 20.1 0.0 0.00099 18.0 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EKG10540.1 - 0.00062 19.7 0.0 0.0036 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EKG10540.1 - 0.00074 18.9 0.2 0.98 8.7 0.1 2.9 2 1 1 3 3 3 2 AAA domain USP8_dimer PF08969.6 EKG10540.1 - 0.00077 19.4 1.0 0.0017 18.3 0.7 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain Zeta_toxin PF06414.7 EKG10540.1 - 0.0043 16.1 0.1 0.1 11.7 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 EKG10540.1 - 0.0083 15.3 0.1 0.027 13.6 0.0 1.8 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EKG10540.1 - 0.012 15.1 0.2 0.036 13.6 0.0 2.0 3 0 0 3 3 2 0 AAA domain PhoH PF02562.11 EKG10540.1 - 0.029 13.5 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 EKG10540.1 - 0.039 14.2 0.3 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EKG10540.1 - 0.051 13.2 0.0 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.6 EKG10540.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Torsin Arch_ATPase PF01637.13 EKG10540.1 - 0.059 13.0 0.2 0.52 9.9 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase ResIII PF04851.10 EKG10540.1 - 0.067 13.0 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EKG10540.1 - 0.077 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 EKG10540.1 - 0.097 12.4 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EKG10540.1 - 0.16 11.0 0.0 13 4.8 0.0 2.4 1 1 1 2 2 2 0 KaiC TPR_1 PF00515.23 EKG10540.1 - 4.7 6.9 6.1 0.71 9.5 0.3 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Prenylcys_lyase PF07156.9 EKG10542.1 - 9.5e-36 123.4 0.0 1.1e-21 77.2 0.0 2.3 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EKG10542.1 - 6.1e-11 42.1 2.1 1.1e-10 41.3 0.2 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EKG10542.1 - 2.3e-07 30.2 0.0 9.3e-07 28.2 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EKG10542.1 - 0.00019 21.2 0.3 0.00078 19.2 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EKG10542.1 - 0.0002 20.3 1.1 0.00057 18.8 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG10542.1 - 0.0082 16.0 0.3 0.092 12.6 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG10542.1 - 0.018 15.1 0.1 0.088 12.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GRIM-19 PF06212.7 EKG10544.1 - 7.8e-24 83.8 0.1 1.8e-23 82.6 0.1 1.5 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 EKG10545.1 - 1.2e-31 109.7 0.2 6e-24 84.6 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Aldedh PF00171.17 EKG10546.1 - 2.3e-18 65.8 0.0 2.6e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 EKG10547.1 - 9.5e-13 47.8 0.0 1.1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Abhydrolase_4 PF08386.5 EKG10550.1 - 4.6e-09 36.0 0.0 7.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein MIF4G PF02854.14 EKG10551.1 - 1.4e-10 40.9 0.0 3.7e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 MIF4G domain HYR PF02494.11 EKG10553.1 - 0.006 16.5 3.0 0.006 16.5 2.1 2.5 1 1 1 2 2 2 1 HYR domain Big_3_2 PF12245.3 EKG10553.1 - 1.1 8.8 6.4 12 5.5 1.9 4.1 2 2 0 2 2 2 0 Bacterial Ig-like domain (group 3) AAA_26 PF13500.1 EKG10555.1 - 5.5e-34 117.5 0.0 9e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.16 EKG10555.1 - 4.9e-33 114.3 0.0 4e-21 75.2 0.0 2.8 2 1 0 2 2 2 2 Aminotransferase class-III BATS PF06968.8 EKG10556.1 - 6e-30 102.9 0.0 1.6e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EKG10556.1 - 9.4e-15 55.1 0.0 1.9e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Pyr_redox_3 PF13738.1 EKG10557.1 - 6.2e-22 78.6 0.0 1e-21 77.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG10557.1 - 1.5e-18 66.3 0.0 1.3e-16 59.8 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG10557.1 - 1.9e-10 40.5 0.0 6.8e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG10557.1 - 4.4e-06 25.8 0.0 0.0019 17.1 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EKG10557.1 - 6.1e-06 25.3 0.0 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EKG10557.1 - 8.1e-05 22.4 0.3 0.025 14.3 0.0 3.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG10557.1 - 0.00017 21.5 0.0 0.001 19.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG10557.1 - 0.015 14.4 0.6 0.024 13.7 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EKG10557.1 - 0.12 12.7 0.5 5.3 7.5 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG10557.1 - 0.15 10.9 0.0 0.33 9.8 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EKG10557.1 - 0.27 10.2 0.4 0.41 9.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NmrA PF05368.8 EKG10558.1 - 1.1e-08 34.6 0.0 2.5e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EKG10558.1 - 0.011 15.2 0.3 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TauD PF02668.11 EKG10559.1 - 1.1e-34 120.2 0.2 1.4e-34 119.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Dopey_N PF04118.9 EKG10565.1 - 7.9e-95 317.1 0.0 2.8e-94 315.3 0.0 1.9 2 0 0 2 2 2 1 Dopey, N-terminal Alpha-amylase PF00128.19 EKG10567.1 - 1.9e-97 326.4 1.6 2.2e-97 326.2 0.2 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 EKG10567.1 - 7.8e-05 22.7 0.0 0.00046 20.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.13 EKG10567.1 - 0.003 17.6 0.0 0.0087 16.1 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 EKG10567.1 - 0.0031 16.4 0.0 0.012 14.5 0.0 1.9 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_42C PF08533.5 EKG10567.1 - 0.065 12.7 0.2 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Sugar_tr PF00083.19 EKG10568.1 - 6.7e-82 275.4 22.0 7.8e-82 275.2 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG10568.1 - 2.8e-19 69.0 18.8 2.8e-19 69.0 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG10568.1 - 3.8e-06 25.5 2.3 3.8e-06 25.5 1.6 3.4 3 1 1 4 4 4 3 MFS/sugar transport protein Tho2 PF11262.3 EKG10569.1 - 0.058 12.4 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 COesterase PF00135.23 EKG10570.1 - 5.5e-88 295.9 0.0 8.2e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG10570.1 - 1.9e-12 47.1 0.1 1.6e-10 40.9 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG10570.1 - 2.3e-06 26.9 1.0 2e-05 23.9 0.9 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG10570.1 - 0.0003 20.5 0.6 0.00074 19.2 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Microtub_assoc PF07989.6 EKG10571.1 - 1.5e-21 75.9 8.9 1.5e-21 75.9 6.2 11.1 9 6 4 13 13 13 1 Microtubule associated PACT_coil_coil PF10495.4 EKG10571.1 - 1.4e-20 73.0 0.4 5e-20 71.2 0.3 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Reo_sigmaC PF04582.7 EKG10571.1 - 1.3e-10 41.0 44.4 0.00089 18.5 1.2 7.1 1 1 5 7 7 7 6 Reovirus sigma C capsid protein GAS PF13851.1 EKG10571.1 - 0.21 10.7 170.6 0.03 13.5 12.7 10.5 2 2 6 10 10 10 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EKG10571.1 - 0.3 9.4 120.9 0.091 11.2 24.2 5.0 1 1 4 5 5 5 0 AAA domain SGT1 PF07093.6 EKG10572.1 - 1.3e-146 489.4 28.6 1e-144 483.1 19.8 2.0 1 1 0 1 1 1 1 SGT1 protein PCI_Csn8 PF10075.4 EKG10573.1 - 2.5e-35 121.3 0.0 3.6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EKG10573.1 - 2.9e-20 72.7 0.0 3.8e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF2497 PF10691.4 EKG10573.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2497) PDCD2_C PF04194.8 EKG10574.1 - 7.7e-56 188.1 1.3 4e-54 182.6 0.0 2.8 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Zn_ribbon_recom PF13408.1 EKG10574.1 - 0.059 13.6 0.6 9.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF3113 PF11310.3 EKG10574.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) LETM1 PF07766.8 EKG10575.1 - 1.3e-11 44.1 0.1 2.5e-07 30.0 0.1 2.1 2 0 0 2 2 2 2 LETM1-like protein Vps55 PF04133.9 EKG10575.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 55 adh_short PF00106.20 EKG10576.1 - 4.5e-29 101.5 0.1 8.3e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10576.1 - 1.2e-09 38.0 1.4 7.6e-09 35.4 0.9 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG10576.1 - 1.1e-08 35.2 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EKG10576.1 - 2.7e-07 29.5 0.0 4e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG10576.1 - 2.6e-06 27.5 0.1 6.1e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG10576.1 - 0.00028 20.3 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ureidogly_hydro PF04115.7 EKG10576.1 - 0.052 12.9 0.1 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Ureidoglycolate hydrolase COesterase PF00135.23 EKG10577.1 - 4.9e-61 207.0 0.0 6.2e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG10577.1 - 1.7e-05 24.5 0.3 4.6e-05 23.0 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold ABC2_membrane PF01061.19 EKG10578.1 - 1.5e-88 295.4 47.8 1.9e-49 167.7 12.1 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EKG10578.1 - 5.3e-39 133.6 0.0 1.5e-18 67.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG10578.1 - 8e-27 92.9 4.0 1.7e-25 88.6 0.0 3.3 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EKG10578.1 - 2.5e-11 43.1 33.6 2.6e-06 26.7 10.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EKG10578.1 - 4.7e-10 39.4 0.3 1.2e-09 38.0 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EKG10578.1 - 2.4e-05 23.8 0.0 0.011 15.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EKG10578.1 - 7.5e-05 22.2 0.4 0.33 10.3 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKG10578.1 - 0.00018 21.6 0.1 0.09 12.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKG10578.1 - 0.0004 19.6 0.1 0.0075 15.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG10578.1 - 0.0014 18.6 0.3 0.076 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EKG10578.1 - 0.0037 16.7 0.6 0.078 12.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 EKG10578.1 - 0.0046 16.4 0.6 1.5 8.3 0.1 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EKG10578.1 - 0.0057 16.6 0.4 0.31 10.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG10578.1 - 0.012 16.3 0.0 0.97 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EKG10578.1 - 0.026 14.8 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EKG10578.1 - 0.038 13.9 0.0 1.5 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EKG10578.1 - 0.047 13.5 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EKG10578.1 - 0.076 12.7 0.2 21 4.9 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Dynamin_N PF00350.18 EKG10578.1 - 0.13 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Dynamin family NACHT PF05729.7 EKG10578.1 - 0.18 11.4 0.7 3.8 7.1 0.2 2.3 2 0 0 2 2 2 0 NACHT domain IU_nuc_hydro PF01156.14 EKG10579.1 - 1.5e-22 80.2 0.0 1.8e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ADH_N PF08240.7 EKG10580.1 - 2.1e-27 95.0 2.6 2.1e-27 95.0 1.8 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG10580.1 - 3.4e-18 65.4 0.1 5.2e-18 64.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG10580.1 - 7.7e-06 26.8 0.1 3.5e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase dTMP_synthase PF02593.9 EKG10580.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase 2-Hacid_dh_C PF02826.14 EKG10580.1 - 0.02 14.0 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EKG10580.1 - 0.029 13.9 0.3 0.05 13.1 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CoA_binding PF02629.14 EKG10580.1 - 0.033 14.6 0.1 0.11 13.0 0.1 1.9 1 0 0 1 1 1 0 CoA binding domain ThiF PF00899.16 EKG10580.1 - 0.11 12.3 0.4 1.7 8.4 0.2 2.2 1 1 1 2 2 2 0 ThiF family DUF3397 PF11877.3 EKG10581.1 - 0.17 11.8 7.0 0.27 11.2 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3397) Fungal_trans_2 PF11951.3 EKG10583.1 - 6.2e-07 28.3 0.4 2.9e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG10583.1 - 1.3e-05 25.0 11.2 3.1e-05 23.7 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF755 PF05501.6 EKG10583.1 - 0.31 11.1 26.8 1.1 9.3 11.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Period_C PF12114.3 EKG10583.1 - 9.4 5.7 15.9 2 7.9 7.6 2.0 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Acyl-CoA_dh_1 PF00441.19 EKG10585.1 - 3.9e-23 82.2 0.2 6.5e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG10585.1 - 7.2e-08 32.9 0.1 1.7e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EKG10585.1 - 0.0044 17.2 0.2 0.01 16.0 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Aldo_ket_red PF00248.16 EKG10586.1 - 5.1e-14 51.7 0.1 5.8e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COG6 PF06419.6 EKG10586.1 - 0.13 10.3 0.0 0.14 10.2 0.0 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Aldo_ket_red PF00248.16 EKG10587.1 - 0.15 10.8 0.0 0.41 9.4 0.0 1.7 2 0 0 2 2 2 0 Aldo/keto reductase family Dicty_CAR PF05462.6 EKG10588.1 - 3.1e-07 29.5 1.4 6.5e-07 28.5 1.0 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EKG10588.1 - 3.1e-06 26.9 2.8 3.1e-06 26.9 2.0 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 DUF572 PF04502.8 EKG10588.1 - 0.014 14.5 3.9 0.023 13.9 2.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Zea_mays_MuDR PF05928.6 EKG10588.1 - 0.13 11.6 0.6 0.19 11.1 0.4 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) CDC45 PF02724.9 EKG10588.1 - 2.2 6.1 5.3 1 7.2 2.1 1.5 2 0 0 2 2 2 0 CDC45-like protein Sugar_tr PF00083.19 EKG10590.1 - 0.016 13.8 3.0 0.019 13.5 2.1 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.11 EKG10590.1 - 0.051 12.2 6.6 0.066 11.9 4.6 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily MFS_1 PF07690.11 EKG10591.1 - 8.9e-16 57.5 12.5 1.1e-15 57.2 8.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PRANC PF09372.5 EKG10591.1 - 0.033 14.1 0.2 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 PRANC domain F-box PF00646.28 EKG10591.1 - 0.067 12.8 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box domain Solute_trans_a PF03619.11 EKG10592.1 - 1.3e-49 169.0 13.2 3.3e-49 167.6 9.1 1.6 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Frag1 PF10277.4 EKG10592.1 - 3.2 7.1 17.8 0.45 9.9 2.6 3.1 1 1 0 3 3 3 0 Frag1/DRAM/Sfk1 family Sugar_tr PF00083.19 EKG10593.1 - 1.8e-101 339.9 23.2 2.1e-101 339.7 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG10593.1 - 5.8e-25 87.7 33.2 4.7e-24 84.7 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EKG10593.1 - 0.0029 15.7 3.8 0.0062 14.6 2.6 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EKG10593.1 - 0.16 11.7 6.3 0.15 11.8 0.4 3.0 2 0 0 2 2 2 0 MFS_1 like family SGL PF08450.7 EKG10594.1 - 1.8e-21 76.6 0.0 3.6e-21 75.6 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EKG10594.1 - 0.017 15.0 0.0 0.73 9.8 0.0 2.7 3 0 0 3 3 3 0 Arylesterase adh_short PF00106.20 EKG10595.1 - 3.1e-17 63.0 3.3 5e-17 62.3 2.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10595.1 - 5.4e-10 39.2 0.7 7.9e-10 38.6 0.5 1.3 1 0 0 1 1 1 1 KR domain ADH_N PF08240.7 EKG10596.1 - 6.5e-19 67.7 4.8 1.2e-18 66.8 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG10596.1 - 1.7e-11 43.7 0.0 3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG10596.1 - 0.0006 19.0 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EKG10597.1 - 4.7e-14 52.6 1.0 1.5e-13 50.9 0.2 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG10597.1 - 4.4e-08 32.9 1.2 4.9e-08 32.8 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EKG10597.1 - 0.004 16.6 0.0 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG10597.1 - 0.018 13.9 0.0 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 EKG10597.1 - 0.039 12.8 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EKG10597.1 - 0.069 13.1 1.1 0.76 9.7 0.3 2.2 2 0 0 2 2 2 0 NADH(P)-binding Pyr_redox_3 PF13738.1 EKG10598.1 - 5.5e-22 78.8 0.0 9.7e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG10598.1 - 1.8e-13 49.5 0.4 8.7e-12 44.0 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG10598.1 - 2e-11 43.7 0.0 5.6e-10 39.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG10598.1 - 1.5e-08 34.7 0.0 5.3e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG10598.1 - 1.6e-07 30.5 0.4 8.8e-05 21.5 0.0 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EKG10598.1 - 1.8e-07 30.3 0.0 1.2e-06 27.6 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EKG10598.1 - 0.00017 20.7 0.0 0.00039 19.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EKG10598.1 - 0.00028 19.8 0.0 0.00047 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EKG10598.1 - 0.0019 18.5 0.2 0.093 13.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG10598.1 - 0.0092 15.7 1.5 0.94 9.2 0.2 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EKG10598.1 - 0.014 14.3 0.1 0.061 12.2 0.0 2.1 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EKG10598.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EKG10598.1 - 0.057 12.2 0.0 1 8.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EKG10598.1 - 0.15 10.5 0.2 0.75 8.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein SR-25 PF10500.4 EKG10599.1 - 3.1 7.2 23.0 6.3 6.1 16.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mitofilin PF09731.4 EKG10600.1 - 2.9e-06 26.2 3.8 4e-06 25.7 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.13 EKG10600.1 - 0.00088 18.8 11.3 0.0015 18.1 7.8 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Seryl_tRNA_N PF02403.17 EKG10600.1 - 0.032 14.2 3.8 0.042 13.8 0.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 EKG10600.1 - 0.06 11.8 3.7 0.081 11.3 2.6 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 EKG10600.1 - 0.14 11.9 1.5 0.99 9.2 0.2 2.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF342 PF03961.8 EKG10600.1 - 0.38 9.1 2.8 0.51 8.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 EKG10600.1 - 0.39 10.5 6.2 0.52 10.1 1.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COMP PF11598.3 EKG10600.1 - 0.4 10.7 2.0 2.4 8.2 0.0 2.7 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein COG2 PF06148.6 EKG10600.1 - 2.5 7.9 8.5 6.4 6.6 2.5 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 OmpH PF03938.9 EKG10600.1 - 3.3 7.6 11.2 0.62 9.9 1.1 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GMC_oxred_C PF05199.8 EKG10601.1 - 0.015 15.6 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase DAO PF01266.19 EKG10602.1 - 0.00014 20.9 1.1 0.00021 20.3 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG10602.1 - 0.0012 18.8 1.0 0.0024 17.8 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG10602.1 - 0.027 13.3 1.3 0.04 12.7 0.9 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EKG10602.1 - 0.09 11.6 0.5 0.13 11.2 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.20 EKG10603.1 - 0.00013 21.9 0.8 0.00017 21.5 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 EKG10603.1 - 0.00065 18.9 0.0 0.00072 18.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) BTB PF00651.26 EKG10604.1 - 0.11 12.5 0.0 0.92 9.5 0.0 2.4 3 0 0 3 3 3 0 BTB/POZ domain KR PF08659.5 EKG10605.1 - 1.1e-54 184.8 0.0 4e-53 179.7 0.0 2.7 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EKG10605.1 - 9.4e-44 150.0 0.0 1.5e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EKG10605.1 - 1.1e-42 145.8 0.0 1.9e-39 135.2 0.0 3.0 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 EKG10605.1 - 4.7e-39 134.3 2.3 7.5e-39 133.6 0.7 2.0 2 0 0 2 2 2 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EKG10605.1 - 2e-20 72.6 0.0 9.3e-20 70.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EKG10605.1 - 1.1e-14 54.7 0.0 3.2e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10605.1 - 8.5e-10 39.0 0.0 2.9e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EKG10605.1 - 5.1e-09 37.0 0.0 3.8e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EKG10605.1 - 1e-08 35.7 0.0 4.6e-08 33.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG10605.1 - 2.9e-08 33.5 0.0 1.2e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10605.1 - 3.7e-08 33.1 0.0 4.5e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG10605.1 - 0.00012 21.2 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EKG10605.1 - 0.00022 21.4 0.0 0.00051 20.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_7 PF03492.10 EKG10607.1 - 1.8e-23 82.8 0.0 4.6e-22 78.2 0.0 2.5 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase ADH_zinc_N PF00107.21 EKG10608.1 - 7.4e-25 87.0 1.7 1.2e-24 86.2 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG10608.1 - 1.6e-21 76.0 0.4 1.6e-21 76.0 0.3 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EKG10609.1 - 1e-20 73.6 0.0 1.2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_17 PF00332.13 EKG10610.1 - 0.00015 20.9 0.0 0.004 16.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Ras PF00071.17 EKG10611.1 - 3.3e-41 140.3 0.0 3.9e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG10611.1 - 2.3e-13 50.6 0.0 3.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG10611.1 - 4.7e-06 25.9 0.0 5.5e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKG10611.1 - 0.00011 22.1 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG10611.1 - 0.0021 17.4 0.0 0.064 12.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PRK PF00485.13 EKG10611.1 - 0.045 13.3 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SIS_2 PF13580.1 EKG10611.1 - 0.057 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SIS domain Epimerase PF01370.16 EKG10612.1 - 5.8e-10 38.9 0.0 9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG10612.1 - 8.3e-06 25.9 0.0 3.2e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EKG10612.1 - 2.1e-05 23.5 0.0 3.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Y_phosphatase PF00102.22 EKG10613.1 - 2.2e-55 187.5 0.0 3e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EKG10613.1 - 0.0023 17.5 0.1 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Zn_clus PF00172.13 EKG10614.1 - 4.2e-09 36.1 13.2 6.6e-09 35.5 9.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 EKG10615.1 - 2.9e-61 207.1 0.0 3.7e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Bacteriocin_IIi PF11758.3 EKG10615.1 - 0.032 13.8 0.5 0.071 12.7 0.3 1.6 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin VID27 PF08553.5 EKG10615.1 - 0.1 10.7 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ion_trans PF00520.26 EKG10616.1 - 0.0028 16.9 14.3 0.0046 16.2 5.5 3.2 3 1 0 3 3 3 1 Ion transport protein PKD_channel PF08016.7 EKG10616.1 - 0.091 11.1 6.9 0.31 9.4 0.5 2.3 2 0 0 2 2 2 0 Polycystin cation channel Chitin_bind_1 PF00187.14 EKG10617.1 - 6.7e-06 25.9 62.9 9.3e-05 22.3 13.5 4.1 3 1 1 4 4 4 3 Chitin recognition protein Glyco_hydro_72 PF03198.9 EKG10619.1 - 1.7e-136 454.3 10.7 1.7e-136 454.3 7.4 1.4 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.8 EKG10619.1 - 2.1e-25 88.9 3.8 7.1e-25 87.3 2.6 2.0 1 0 0 1 1 1 1 X8 domain SnoaL_3 PF13474.1 EKG10620.1 - 0.018 15.0 1.6 0.03 14.3 1.1 1.3 1 0 0 1 1 1 0 SnoaL-like domain Glucan_synthase PF02364.10 EKG10621.1 - 0 1458.9 0.0 0 1458.5 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EKG10621.1 - 1.1e-39 135.0 0.8 2.9e-39 133.6 0.5 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 EKG10622.1 - 5.8e-39 134.0 0.0 7e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EKG10622.1 - 0.086 11.1 0.0 0.17 10.1 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme BPD_transp_2 PF02653.11 EKG10623.1 - 0.0014 17.6 10.8 0.0017 17.3 7.5 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component EpsG PF14897.1 EKG10623.1 - 0.0057 15.6 2.9 0.0068 15.3 2.0 1.2 1 0 0 1 1 1 1 EpsG family Tetraspannin PF00335.15 EKG10623.1 - 9.4 5.4 15.3 0.35 10.1 5.7 1.8 1 1 1 2 2 2 0 Tetraspanin family DUF2207 PF09972.4 EKG10624.1 - 0.058 11.9 0.4 0.065 11.8 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2306 PF10067.4 EKG10624.1 - 0.11 12.5 2.2 0.16 12.0 1.5 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2306) CRAL_TRIO PF00650.15 EKG10625.1 - 2e-36 124.8 0.0 3.2e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EKG10625.1 - 3.4e-08 33.4 1.9 7.7e-08 32.3 0.6 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EKG10625.1 - 1.7e-05 24.7 0.0 4.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Peptidase_C1 PF00112.18 EKG10625.1 - 0.062 13.1 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Papain family cysteine protease HTH_29 PF13551.1 EKG10625.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Zn_clus PF00172.13 EKG10627.1 - 9.3e-09 35.0 12.8 2.5e-08 33.6 8.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EKG10627.1 - 5.2e-05 23.3 13.1 0.00011 22.2 1.1 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG10627.1 - 0.00036 20.6 1.5 0.00036 20.6 1.0 4.8 4 1 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG10627.1 - 0.0011 19.0 4.0 0.0011 19.0 2.8 4.5 4 0 0 4 4 4 1 Zinc-finger double domain Fungal_trans PF04082.13 EKG10627.1 - 0.0014 17.5 0.2 0.0082 15.0 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EKG10629.1 - 1.3e-28 100.3 0.3 1.7e-28 100.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG10629.1 - 6.4e-27 94.4 0.8 9.3e-27 93.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10629.1 - 6.1e-12 45.5 0.4 9e-12 45.0 0.3 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EKG10629.1 - 0.0075 15.3 0.2 0.017 14.1 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EKG10629.1 - 0.04 13.5 1.3 0.061 12.9 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phage_XkdX PF09693.5 EKG10629.1 - 0.13 11.8 0.1 0.99 8.9 0.0 2.3 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Rhomboid PF01694.17 EKG10630.1 - 6.2e-13 49.0 8.6 6.2e-13 49.0 5.9 1.6 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.9 EKG10631.1 - 5.4e-105 351.9 1.4 7e-105 351.6 1.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Glyoxalase_2 PF12681.2 EKG10632.1 - 6.2e-06 26.7 0.0 1.9e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Glyoxalase-like domain Rick_17kDa_Anti PF05433.10 EKG10632.1 - 0.012 15.2 3.2 0.033 13.8 2.2 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EKG10632.1 - 0.06 12.9 4.6 0.16 11.5 3.2 1.7 1 0 0 1 1 1 0 Glycine zipper EMG1 PF03587.9 EKG10633.1 - 1.3e-80 269.4 0.0 1.5e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase adh_short_C2 PF13561.1 EKG10634.1 - 1.7e-25 90.1 0.0 1.9e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG10634.1 - 1.8e-23 83.2 0.0 2.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG10634.1 - 8.2e-08 32.1 0.0 1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_6 PF08030.7 EKG10635.1 - 8.9e-33 113.3 0.0 1.5e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG10635.1 - 5.1e-20 71.3 0.0 1.4e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EKG10635.1 - 1.5e-17 63.8 19.4 2.4e-17 63.2 8.8 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EKG10635.1 - 0.00038 20.5 0.0 0.00097 19.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EKG10635.1 - 0.066 13.7 0.0 0.72 10.4 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Transferase PF02458.10 EKG10636.1 - 7.5e-28 97.1 0.0 1.8e-26 92.6 0.0 2.2 1 1 0 1 1 1 1 Transferase family NACHT PF05729.7 EKG10637.1 - 4.5e-07 29.6 0.4 3.5e-06 26.7 0.3 2.4 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EKG10637.1 - 2.1e-05 24.6 0.0 0.0001 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EKG10637.1 - 0.00065 20.0 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EKG10637.1 - 0.001 17.9 0.1 0.003 16.4 0.1 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 EKG10637.1 - 0.0018 17.7 0.0 0.19 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EKG10637.1 - 0.0038 18.0 0.0 0.021 15.6 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EKG10637.1 - 0.0075 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG10637.1 - 0.0092 15.9 0.3 0.05 13.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EKG10637.1 - 0.011 15.2 0.2 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EKG10637.1 - 0.036 13.2 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EKG10637.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EKG10637.1 - 0.059 12.9 0.2 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ank PF00023.25 EKG10637.1 - 0.12 12.1 0.0 8.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat DUF2075 PF09848.4 EKG10637.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 EKG10637.1 - 0.16 12.2 0.2 0.36 11.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 EKG10637.1 - 0.24 10.8 0.0 0.44 9.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Herpes_Helicase PF02689.9 EKG10637.1 - 0.4 8.3 0.0 0.65 7.6 0.0 1.3 1 0 0 1 1 1 0 Helicase Ytp1 PF10355.4 EKG10639.1 - 2.9e-110 367.7 10.5 4e-110 367.2 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EKG10639.1 - 2e-24 85.1 12.0 2.1e-23 81.8 2.4 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DASH_Dam1 PF08653.5 EKG10640.1 - 5.1e-29 99.8 1.5 7.5e-29 99.2 1.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 EKG10641.1 - 2.2e-45 153.9 0.0 3.3e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EKG10641.1 - 3.7e-14 52.5 0.0 1.6e-13 50.5 0.0 2.2 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EKG10641.1 - 5.4e-11 42.6 0.0 8.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EGF_alliinase PF04863.8 EKG10641.1 - 0.52 10.3 0.0 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 Alliinase EGF-like domain CBS PF00571.23 EKG10642.1 - 7.3e-19 67.2 4.1 1.3e-07 31.2 0.1 5.3 5 0 0 5 5 5 5 CBS domain PH PF00169.24 EKG10645.1 - 2.8e-10 40.3 0.0 5.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EKG10645.1 - 0.027 12.0 0.2 0.037 11.5 0.2 1.1 1 0 0 1 1 1 0 Prominin Acetone_carb_G PF08882.6 EKG10645.1 - 0.072 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit PCMT PF01135.14 EKG10646.1 - 4.6e-66 222.3 0.0 5.1e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EKG10646.1 - 1.8e-11 44.6 0.0 2.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10646.1 - 5.6e-11 42.2 0.0 8.2e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG10646.1 - 1.3e-05 25.0 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EKG10646.1 - 6.7e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10646.1 - 9.1e-05 22.8 0.0 0.00019 21.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG10646.1 - 9.4e-05 22.4 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG10646.1 - 0.00013 22.2 0.0 0.00031 21.0 0.0 1.7 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG10646.1 - 0.00017 20.8 0.0 0.00022 20.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EKG10646.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EKG10646.1 - 0.0019 18.6 0.0 0.0029 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKG10646.1 - 0.0028 17.6 0.0 0.0042 17.0 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase GCD14 PF08704.5 EKG10646.1 - 0.0033 16.9 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 EKG10646.1 - 0.0059 15.7 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EKG10646.1 - 0.0063 15.5 0.0 0.0084 15.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EKG10646.1 - 0.0079 15.2 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_3 PF01596.12 EKG10646.1 - 0.026 13.5 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_24 PF13578.1 EKG10646.1 - 0.03 15.1 0.0 0.066 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EKG10646.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_16 PF10294.4 EKG10646.1 - 0.084 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase ketoacyl-synt PF00109.21 EKG10648.1 - 9e-78 261.2 0.0 2.5e-77 259.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG10648.1 - 2.7e-51 174.7 0.6 5.1e-49 167.3 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG10648.1 - 2.1e-33 114.6 3.0 6.8e-33 113.0 2.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EKG10648.1 - 9.9e-29 101.1 0.0 1.2e-27 97.6 0.0 2.8 3 1 0 3 3 3 1 Thioesterase domain PP-binding PF00550.20 EKG10648.1 - 6.6e-25 87.1 5.9 1.2e-12 47.8 0.5 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 EKG10648.1 - 5e-15 55.4 0.0 1.3e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 EKG10648.1 - 1.4e-06 28.4 0.0 0.0015 18.5 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG10648.1 - 1.3e-05 24.9 0.1 0.049 13.3 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EKG10648.1 - 8.3e-05 21.6 0.1 0.00023 20.2 0.0 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.8 EKG10648.1 - 0.0017 18.0 0.2 0.0059 16.2 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EKG10648.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF3740 PF12548.3 EKG10648.1 - 0.34 11.1 0.1 0.99 9.6 0.0 1.7 1 0 0 1 1 1 0 Sulfatase protein COX6B PF02297.12 EKG10649.1 - 2.1e-24 85.3 6.0 2.5e-24 85.0 4.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EKG10649.1 - 0.0034 17.3 1.6 0.0053 16.7 1.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Prolamin_like PF05617.6 EKG10649.1 - 0.093 12.8 0.6 0.12 12.4 0.4 1.2 1 0 0 1 1 1 0 Prolamin-like DUF2263 PF10021.4 EKG10650.1 - 6e-27 94.4 0.0 8.6e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) tRNA-synt_2 PF00152.15 EKG10651.1 - 9.8e-68 228.3 0.0 1.5e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) CHASE2 PF05226.6 EKG10651.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 CHASE2 domain tRNA-synt_2d PF01409.15 EKG10651.1 - 0.025 13.7 0.1 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Mito_carr PF00153.22 EKG10652.1 - 1.4e-71 236.2 1.7 3.5e-25 87.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AAA PF00004.24 EKG10653.1 - 3.4e-39 134.0 0.0 7.3e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG10653.1 - 1.2e-06 28.6 2.4 7.7e-05 22.8 0.1 3.6 4 1 0 4 4 2 1 AAA domain RuvB_N PF05496.7 EKG10653.1 - 2.9e-05 23.2 0.0 5.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKG10653.1 - 0.00025 21.0 1.4 0.00076 19.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EKG10653.1 - 0.00031 20.7 0.0 0.00066 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EKG10653.1 - 0.00038 19.3 0.1 0.00071 18.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EKG10653.1 - 0.00083 19.0 0.0 0.003 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EKG10653.1 - 0.00085 20.1 0.3 0.14 12.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EKG10653.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EKG10653.1 - 0.003 17.2 0.1 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EKG10653.1 - 0.0036 16.7 0.2 0.2 11.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EKG10653.1 - 0.0037 16.4 0.1 0.0073 15.4 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EKG10653.1 - 0.0043 16.9 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG10653.1 - 0.0045 16.5 0.2 0.014 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 EKG10653.1 - 0.0055 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EKG10653.1 - 0.0083 16.0 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EKG10653.1 - 0.031 13.8 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKG10653.1 - 0.031 13.9 0.0 0.1 12.3 0.0 2.0 2 1 0 2 2 1 0 Archaeal ATPase AAA_28 PF13521.1 EKG10653.1 - 0.036 14.0 1.4 0.2 11.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 EKG10653.1 - 0.062 13.3 0.0 0.56 10.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EKG10653.1 - 0.069 13.4 0.1 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Guanylate_kin PF00625.16 EKG10653.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.7 1 1 0 1 1 1 0 Guanylate kinase AAA_18 PF13238.1 EKG10653.1 - 0.086 13.1 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EKG10653.1 - 0.09 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain PhoH PF02562.11 EKG10653.1 - 0.12 11.5 0.2 0.32 10.1 0.1 1.5 1 1 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 EKG10653.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EKG10653.1 - 0.24 10.4 0.2 3.3 6.7 0.0 2.2 1 1 1 2 2 2 0 KaiC IQ PF00612.22 EKG10654.1 - 1.5e-07 30.3 5.4 0.011 15.2 0.2 4.0 3 0 0 3 3 3 3 IQ calmodulin-binding motif CH PF00307.26 EKG10654.1 - 1.4e-06 28.2 0.0 0.0041 17.1 0.0 3.5 2 1 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EKG10654.1 - 8.2e-06 25.3 0.0 0.05 13.2 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain Methyltransf_26 PF13659.1 EKG10655.1 - 4e-17 62.3 0.3 5.8e-17 61.8 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG10655.1 - 1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EKG10655.1 - 0.016 15.6 0.0 0.03 14.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10655.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10655.1 - 0.074 13.6 0.1 0.22 12.0 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EKG10655.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.10 EKG10656.1 - 5.4e-09 35.7 0.0 1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EKG10656.1 - 1e-08 35.2 0.1 2.7e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EKG10656.1 - 3.9e-07 30.5 0.2 5.6e-07 29.9 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like MerR-DNA-bind PF09278.6 EKG10656.1 - 0.055 13.8 1.8 1.7 9.0 0.0 2.3 2 0 0 2 2 2 0 MerR, DNA binding Metal_resist PF13801.1 EKG10656.1 - 2.1 8.3 6.3 8.3 6.4 0.6 2.4 2 0 0 2 2 2 0 Heavy-metal resistance TauD PF02668.11 EKG10657.1 - 3.4e-26 92.4 0.0 4.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LSM PF01423.17 EKG10658.1 - 5.8e-17 60.9 0.2 7.7e-17 60.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKG10658.1 - 0.0002 21.2 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF3247 PF11607.3 EKG10658.1 - 0.026 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DUF2763 PF10961.3 EKG10658.1 - 0.066 13.6 4.4 0.11 12.8 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) HlyD_3 PF13437.1 EKG10658.1 - 0.12 12.6 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Tail_tube PF10618.4 EKG10658.1 - 0.13 12.0 0.4 0.59 9.8 0.3 1.9 1 1 1 2 2 2 0 Phage tail tube protein API5 PF05918.6 EKG10658.1 - 0.14 10.6 9.5 0.17 10.3 6.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Pkr1 PF08636.5 EKG10659.1 - 4.5e-36 122.7 4.9 4.5e-36 122.7 3.4 1.4 2 0 0 2 2 2 1 ER protein Pkr1 FHIPEP PF00771.15 EKG10659.1 - 0.0023 16.3 0.0 0.0031 15.9 0.0 1.1 1 0 0 1 1 1 1 FHIPEP family OAD_gamma PF04277.8 EKG10659.1 - 0.015 15.6 0.2 0.064 13.6 0.0 2.0 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CAAD PF14159.1 EKG10659.1 - 0.058 13.0 0.1 0.095 12.3 0.1 1.2 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase CMS1 PF14617.1 EKG10659.1 - 0.47 9.4 2.8 1.2 8.2 1.5 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PGA2 PF07543.7 EKG10659.1 - 9 6.0 12.7 3.2 7.5 6.7 1.5 1 1 1 2 2 2 0 Protein trafficking PGA2 Sugar_tr PF00083.19 EKG10660.1 - 8.3e-112 374.0 16.2 1.5e-111 373.2 11.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG10660.1 - 2.5e-25 88.9 45.2 9.3e-22 77.2 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG10660.1 - 5.9e-06 24.7 6.4 0.001 17.3 2.0 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) UPF0640 PF15114.1 EKG10660.1 - 0.1 12.0 2.2 0.12 11.8 0.1 2.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0640 DEAD PF00270.24 EKG10661.1 - 1.7e-22 79.7 0.4 1e-21 77.1 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase RQC PF09382.5 EKG10661.1 - 1.1e-21 76.4 0.1 2.4e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 EKG10661.1 - 5.6e-21 74.1 0.3 7.8e-18 64.1 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain HRDC PF00570.18 EKG10661.1 - 1e-07 31.5 0.0 5.5e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 HRDC domain SNF2_N PF00176.18 EKG10661.1 - 0.00076 18.3 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HHH PF00633.18 EKG10661.1 - 0.13 12.0 0.2 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pyridoxal_deC PF00282.14 EKG10662.1 - 1.6e-26 92.6 0.0 2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EKG10662.1 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Dioxygenase_C PF00775.16 EKG10663.1 - 9.8e-13 47.7 0.1 2.4e-12 46.4 0.1 1.8 1 1 0 1 1 1 1 Dioxygenase DUF4406 PF14359.1 EKG10663.1 - 0.11 12.5 0.1 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) DNA_ligase_A_M PF01068.16 EKG10664.1 - 4.2e-50 169.9 0.2 2.3e-47 160.9 0.0 2.6 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EKG10664.1 - 1e-39 136.1 0.0 2.5e-39 134.9 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EKG10664.1 - 3e-19 69.2 0.0 6.5e-17 61.7 0.0 3.4 3 1 0 3 3 3 1 ATP dependent DNA ligase C terminal region Mog1 PF04603.7 EKG10665.1 - 2.5e-21 76.1 0.2 4.3e-21 75.3 0.1 1.4 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Drf_FH3 PF06367.11 EKG10665.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Diaphanous FH3 Domain Aconitase PF00330.15 EKG10666.1 - 5e-176 585.7 0.0 1.4e-175 584.2 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EKG10666.1 - 7.3e-47 158.7 0.0 1.3e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain COG5 PF10392.4 EKG10667.1 - 4.3e-41 139.9 0.8 1.2e-40 138.5 0.1 2.1 2 0 0 2 2 2 1 Golgi transport complex subunit 5 SAM_2 PF07647.12 EKG10668.1 - 2.3e-09 36.9 0.1 4.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EKG10668.1 - 1.2e-06 28.5 0.3 7e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Glyco_hydro_16 PF00722.16 EKG10669.1 - 2.5e-08 33.4 0.0 6e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 VHS PF00790.14 EKG10670.1 - 1.3e-45 154.5 0.0 4e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EKG10670.1 - 8.6e-25 86.6 2.2 2e-24 85.4 0.7 2.2 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EKG10670.1 - 1.9e-18 66.8 0.6 5.3e-18 65.4 0.4 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Mei5 PF10376.4 EKG10670.1 - 0.0023 17.4 0.9 0.0023 17.4 0.6 1.6 1 1 0 1 1 1 1 Double-strand recombination repair protein GLTSCR1 PF15249.1 EKG10670.1 - 0.84 9.7 4.6 0.4 10.8 0.5 2.2 1 1 1 2 2 2 0 Glioma tumor suppressor candidate region DUF367 PF04034.8 EKG10671.1 - 2.6e-48 162.8 0.1 3.9e-48 162.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EKG10671.1 - 6.2e-09 35.2 0.1 1.3e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI GLTSCR1 PF15249.1 EKG10671.1 - 0.21 11.6 0.0 0.21 11.6 0.0 2.7 3 1 0 3 3 3 0 Glioma tumor suppressor candidate region Abhydrolase_2 PF02230.11 EKG10672.1 - 7.9e-11 41.7 0.0 8.6e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Cutinase PF01083.17 EKG10672.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Cutinase AAA PF00004.24 EKG10673.1 - 1.4e-45 154.6 0.7 5.5e-45 152.8 0.0 2.3 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG10673.1 - 4.9e-09 36.0 0.1 1.7e-08 34.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKG10673.1 - 5.5e-08 32.9 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EKG10673.1 - 2.7e-07 30.7 0.1 2e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG10673.1 - 2.8e-06 27.5 2.4 0.00033 20.8 0.5 2.9 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 EKG10673.1 - 3.3e-06 26.2 0.3 9.1e-06 24.7 0.0 2.0 3 0 0 3 3 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EKG10673.1 - 0.00018 21.3 0.0 0.00076 19.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EKG10673.1 - 0.00044 19.3 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EKG10673.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKG10673.1 - 0.00064 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EKG10673.1 - 0.00083 20.1 0.0 0.0051 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EKG10673.1 - 0.0013 17.5 0.0 0.0023 16.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EKG10673.1 - 0.0014 18.3 0.2 0.0037 16.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EKG10673.1 - 0.0015 18.2 0.2 0.056 13.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_11 PF13086.1 EKG10673.1 - 0.0016 18.0 0.1 0.014 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EKG10673.1 - 0.0023 17.6 0.0 0.0083 15.8 0.0 2.0 2 0 0 2 2 1 1 NTPase AAA_33 PF13671.1 EKG10673.1 - 0.0037 17.1 0.0 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EKG10673.1 - 0.0045 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EKG10673.1 - 0.0049 16.4 0.0 0.043 13.4 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EKG10673.1 - 0.0049 16.5 0.9 0.077 12.6 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase Zeta_toxin PF06414.7 EKG10673.1 - 0.0052 15.8 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EKG10673.1 - 0.006 16.0 0.2 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EKG10673.1 - 0.0069 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EKG10673.1 - 0.0081 16.5 1.3 0.83 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKG10673.1 - 0.011 15.1 1.6 0.084 12.2 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 EKG10673.1 - 0.012 15.1 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EKG10673.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EKG10673.1 - 0.017 14.2 1.1 0.46 9.5 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 EKG10673.1 - 0.017 15.4 0.0 0.053 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EKG10673.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.21 EKG10673.1 - 0.048 13.1 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 EKG10673.1 - 0.057 11.7 0.0 0.09 11.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Sigma54_activ_2 PF14532.1 EKG10673.1 - 0.067 13.2 0.1 0.52 10.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 EKG10673.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EKG10673.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ARID PF01388.16 EKG10674.1 - 6.3e-17 61.2 0.1 6.3e-17 61.2 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Zip PF02535.17 EKG10674.1 - 0.89 8.5 3.5 1.7 7.5 2.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter zf-RING_2 PF13639.1 EKG10675.1 - 4.3e-09 36.0 8.2 7e-09 35.3 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKG10675.1 - 2.7e-06 26.9 5.1 3.9e-06 26.4 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG10675.1 - 7.5e-05 22.6 8.3 0.00012 22.0 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG10675.1 - 0.00011 21.7 6.6 0.00017 21.1 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG10675.1 - 0.0089 16.1 6.6 0.024 14.7 4.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EKG10675.1 - 0.85 9.3 6.0 1.4 8.7 4.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF2410 PF10307.4 EKG10676.1 - 1.8e-80 268.9 0.0 2.5e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) TPR_11 PF13414.1 EKG10678.1 - 3.9e-15 55.2 20.1 0.0061 16.1 1.3 7.3 7 1 0 7 7 7 4 TPR repeat TPR_12 PF13424.1 EKG10678.1 - 3.3e-09 36.5 16.9 0.055 13.4 0.1 6.5 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EKG10678.1 - 2.5e-07 30.9 5.3 0.51 10.7 0.0 6.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKG10678.1 - 6.4e-07 28.7 7.3 2.8 7.6 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG10678.1 - 3.3e-06 26.5 19.6 8.4 6.5 0.0 9.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG10678.1 - 5.1e-06 26.2 6.1 0.028 14.6 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKG10678.1 - 6.4e-05 23.2 24.2 7.7 7.4 0.1 9.9 8 2 2 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG10678.1 - 0.0023 18.5 26.3 0.019 15.5 0.1 8.2 6 3 4 10 10 10 2 Tetratricopeptide repeat TPR_10 PF13374.1 EKG10678.1 - 0.0049 16.7 10.2 0.57 10.1 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKG10678.1 - 0.038 13.7 7.7 31 4.6 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat SYS1 PF09801.4 EKG10679.1 - 7.7e-55 184.8 13.2 8.7e-55 184.6 9.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.7 EKG10679.1 - 1.4 8.6 7.5 0.44 10.3 2.5 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Ran-binding PF05508.6 EKG10681.1 - 0.088 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 RanGTP-binding protein CAP PF00188.21 EKG10683.1 - 1.4e-14 54.6 7.8 2.8e-14 53.6 5.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Acetyltransf_1 PF00583.19 EKG10684.1 - 4.9e-06 26.4 0.3 9.1e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG10684.1 - 0.00093 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG10684.1 - 0.0095 16.0 0.1 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Virul_fac_BrkB PF03631.10 EKG10684.1 - 0.043 13.1 2.9 0.041 13.2 1.3 1.4 1 1 0 1 1 1 0 Virulence factor BrkB Ctr PF04145.10 EKG10684.1 - 0.18 11.8 0.6 0.35 10.9 0.4 1.4 1 0 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.8 EKG10684.1 - 1.4 8.7 12.8 1.8 8.3 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit B12D PF06522.6 EKG10684.1 - 5.8 6.7 5.5 0.52 10.0 0.3 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit BAF1_ABF1 PF04684.8 EKG10684.1 - 9.7 4.9 14.9 14 4.4 10.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pkinase PF00069.20 EKG10685.1 - 2.2e-61 207.2 0.0 6.8e-61 205.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG10685.1 - 1.4e-22 80.0 0.0 4e-22 78.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EKG10685.1 - 0.0022 17.7 0.2 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG10685.1 - 0.012 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Svf1 PF08622.5 EKG10686.1 - 6.1e-135 449.3 0.0 7.3e-135 449.1 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EKG10686.1 - 0.024 13.9 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Hydroxyneurosporene synthase (CrtC) Alpha-amylase PF00128.19 EKG10688.1 - 1.8e-95 319.9 0.0 2.9e-95 319.3 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EKG10688.1 - 0.0002 20.3 0.0 0.00039 19.4 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Imm15 PF15590.1 EKG10688.1 - 0.014 14.4 0.8 0.33 10.0 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 15 Alpha-amylase_C PF02806.13 EKG10688.1 - 0.026 14.6 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain DUF3459 PF11941.3 EKG10688.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Ribosomal_L6 PF00347.18 EKG10690.1 - 9.9e-28 96.4 7.8 2.8e-13 50.1 1.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF4188 PF13826.1 EKG10691.1 - 1.2e-26 93.1 0.4 3.1e-26 91.7 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4188) Dabb PF07876.7 EKG10691.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain DUF883 PF05957.8 EKG10692.1 - 0.13 12.6 10.9 0.39 11.1 3.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 EKG10692.1 - 0.3 11.1 5.1 0.63 10.1 3.6 1.6 1 1 0 1 1 1 0 DivIVA protein ISG65-75 PF11727.3 EKG10692.1 - 0.31 10.0 9.2 0.39 9.7 6.4 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein CsbD PF05532.7 EKG10692.1 - 0.35 10.5 25.7 0.31 10.7 4.5 3.7 2 1 1 3 3 3 0 CsbD-like Borrelia_P83 PF05262.6 EKG10692.1 - 0.41 8.8 8.8 0.43 8.7 6.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein LEA_4 PF02987.11 EKG10692.1 - 3.7 7.4 23.1 38 4.2 12.5 3.1 2 1 0 2 2 2 0 Late embryogenesis abundant protein YtxH PF12732.2 EKG10692.1 - 8.2 6.8 11.2 8.3e+02 0.4 7.7 2.2 1 1 0 1 1 1 0 YtxH-like protein zf-rbx1 PF12678.2 EKG10693.1 - 6.2e-10 39.0 4.0 1.2e-09 38.1 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EKG10693.1 - 4.5e-09 35.9 10.1 5.6e-09 35.6 4.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKG10693.1 - 2.4e-05 23.9 7.7 9.5e-05 21.9 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG10693.1 - 2.6e-05 23.7 3.7 6.8e-05 22.4 2.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG10693.1 - 0.0012 18.7 5.1 0.0012 18.7 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG10693.1 - 0.0028 17.3 7.3 0.021 14.5 5.3 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKG10693.1 - 0.0028 17.4 4.2 0.0055 16.5 1.4 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EKG10693.1 - 0.12 11.9 3.0 0.29 10.7 2.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EKG10693.1 - 3.3 7.3 6.3 1.4 8.5 2.3 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EKG10693.1 - 4.6 7.0 9.1 18 5.1 6.3 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Proteasome PF00227.21 EKG10694.1 - 2.2e-45 154.2 0.0 3e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EKG10694.1 - 5.4e-16 57.5 1.6 1.1e-15 56.5 1.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal CorA PF01544.13 EKG10695.1 - 0.56 9.1 4.3 0.77 8.7 2.6 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3584 PF12128.3 EKG10695.1 - 1.6 5.9 9.1 2.3 5.4 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GTP_EFTU PF00009.22 EKG10696.1 - 1.1e-07 31.5 0.0 5.8e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EKG10696.1 - 0.081 12.4 0.5 0.65 9.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cys_Met_Meta_PP PF01053.15 EKG10698.1 - 2.2e-40 138.1 0.0 2.9e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EKG10698.1 - 0.068 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TPD PF14811.1 EKG10698.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif Nrap PF03813.9 EKG10699.1 - 0 1113.9 0.0 0 1113.7 0.0 1.0 1 0 0 1 1 1 1 Nrap protein GSu_C4xC__C2xCH PF09698.5 EKG10700.1 - 0.028 14.5 0.2 0.072 13.2 0.2 1.8 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ribosomal_S10 PF00338.17 EKG10702.1 - 2.1e-29 101.1 0.5 3e-29 100.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4469 PF14734.1 EKG10702.1 - 0.018 14.8 0.1 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold CUE PF02845.11 EKG10703.1 - 7.5e-11 41.2 0.4 2.7e-10 39.5 0.2 2.0 2 0 0 2 2 2 1 CUE domain APH PF01636.18 EKG10704.1 - 4.8e-08 33.0 0.6 7.1e-08 32.4 0.4 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.12 EKG10705.1 - 2.5e-14 53.3 0.5 1.1e-13 51.3 0.2 2.0 1 1 1 2 2 2 1 THUMP domain eIF3_N PF09440.5 EKG10706.1 - 4.6e-45 153.0 1.7 9.9e-45 151.9 1.1 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EKG10706.1 - 2.3e-15 56.8 0.6 7.4e-15 55.1 0.0 2.2 3 1 0 3 3 3 1 PCI domain RPN7 PF10602.4 EKG10706.1 - 0.0032 16.8 0.0 0.0072 15.7 0.0 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI_Csn8 PF10075.4 EKG10706.1 - 0.017 14.9 0.1 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Img2 PF05046.9 EKG10707.1 - 7.4e-25 87.0 0.1 9e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EKG10707.1 - 9.7e-05 22.1 0.1 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF1699 PF08004.6 EKG10707.1 - 0.087 12.3 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) Lactamase_B_3 PF13483.1 EKG10708.1 - 3.9e-08 33.1 0.0 7.9e-08 32.1 0.0 1.5 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EKG10708.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain GRASP55_65 PF04495.9 EKG10711.1 - 4.2e-49 166.0 0.0 1.2e-46 158.1 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ PF00595.19 EKG10711.1 - 0.011 15.9 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) DUF3459 PF11941.3 EKG10711.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Methyltransf_15 PF09445.5 EKG10712.1 - 1.3e-51 174.4 0.0 1.7e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 EKG10712.1 - 4.7e-09 36.0 0.0 8.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EKG10712.1 - 9.7e-09 35.2 0.0 5.7e-08 32.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 EKG10712.1 - 2.2e-07 30.6 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EKG10712.1 - 3.4e-07 30.8 0.0 9.4e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EKG10712.1 - 1.8e-05 24.1 0.0 2.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EKG10712.1 - 0.00023 20.7 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG10712.1 - 0.0064 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DNA_methylase PF00145.12 EKG10712.1 - 0.007 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase N6_Mtase PF02384.11 EKG10712.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase DUF3591 PF12157.3 EKG10713.1 - 1.9e-175 583.6 0.3 3.1e-175 582.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EKG10713.1 - 0.16 11.6 1.1 0.33 10.6 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EKG10713.1 - 0.32 11.0 0.9 0.74 9.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Linker_histone PF00538.14 EKG10714.1 - 3e-24 84.8 0.6 6.4e-24 83.8 0.4 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family PIP5K PF01504.13 EKG10715.1 - 4.8e-85 284.6 0.6 8.2e-85 283.9 0.4 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase MBOAT PF03062.14 EKG10717.1 - 9.4e-42 143.2 19.8 9.4e-42 143.2 13.7 1.7 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Actin PF00022.14 EKG10718.1 - 1.8e-133 444.8 0.0 2e-133 444.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKG10718.1 - 5.3e-05 21.9 0.3 0.14 10.7 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein MutL PF13941.1 EKG10718.1 - 0.055 11.8 0.0 0.082 11.2 0.0 1.2 1 0 0 1 1 1 0 MutL protein SMC_N PF02463.14 EKG10719.1 - 5.8e-75 251.2 10.4 1.2e-74 250.2 7.2 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKG10719.1 - 4e-29 101.0 0.0 1.3e-28 99.3 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EKG10719.1 - 1.3e-10 41.6 13.4 5.9e-05 23.1 0.6 3.9 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.1 EKG10719.1 - 0.0006 19.2 0.2 0.0018 17.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EKG10719.1 - 0.0014 17.2 10.0 0.0014 17.2 6.9 6.4 3 2 3 6 6 6 3 AAA domain Reo_sigmaC PF04582.7 EKG10719.1 - 0.0059 15.8 1.6 0.0059 15.8 1.1 4.9 2 2 2 5 5 5 3 Reovirus sigma C capsid protein DivIC PF04977.10 EKG10719.1 - 0.0067 15.8 1.0 0.0067 15.8 0.7 12.4 7 6 8 15 15 15 1 Septum formation initiator DUF869 PF05911.6 EKG10719.1 - 0.34 9.0 101.6 0.046 11.9 32.7 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) IncA PF04156.9 EKG10719.1 - 1.3 8.5 121.4 0.12 12.0 12.0 8.1 3 2 3 6 6 6 0 IncA protein ABC2_membrane_3 PF12698.2 EKG10719.1 - 3.4 6.6 2.1 7.1 5.5 1.4 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein BTB PF00651.26 EKG10720.1 - 3.4e-08 33.4 0.0 5.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain C1_1 PF00130.17 EKG10720.1 - 0.051 13.3 4.3 0.097 12.4 3.0 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IBR PF01485.16 EKG10720.1 - 0.47 10.3 7.8 1.4 8.8 5.4 1.7 1 1 0 1 1 1 0 IBR domain FYVE PF01363.16 EKG10720.1 - 0.61 10.0 8.7 1.1 9.1 6.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger KH_1 PF00013.24 EKG10721.1 - 1.1e-39 133.8 3.3 2e-16 59.3 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EKG10721.1 - 4.8e-31 105.8 9.7 4.3e-12 45.3 1.4 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EKG10721.1 - 4e-12 45.5 1.8 0.0046 16.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EKG10721.1 - 0.00042 19.8 0.4 2 8.1 0.0 3.1 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EKG10721.1 - 0.014 15.1 6.1 0.96 9.3 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain CENP-K PF11802.3 EKG10722.1 - 3.6e-08 32.9 0.0 0.0022 17.2 0.1 2.3 2 0 0 2 2 2 2 Centromere-associated protein K DUF3294 PF07957.6 EKG10722.1 - 0.0098 15.4 0.2 0.025 14.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Ribosomal_L29e PF01779.12 EKG10723.1 - 1.6e-23 82.2 10.3 2.2e-23 81.8 7.1 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family CP2 PF04516.10 EKG10725.1 - 8e-86 286.9 0.0 1.3e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 EKG10725.1 - 0.026 13.0 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Tektin family Phage_G PF02306.10 EKG10725.1 - 0.05 13.2 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Major spike protein (G protein) Spo0A_C PF08769.6 EKG10725.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Ureidogly_hydro PF04115.7 EKG10727.1 - 1.6e-55 186.9 0.0 1.9e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase SprT-like PF10263.4 EKG10728.1 - 6.8e-53 178.5 2.6 1.3e-52 177.6 1.8 1.5 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EKG10728.1 - 0.0071 16.2 1.7 0.017 15.0 0.6 2.1 2 0 0 2 2 2 1 Zinc ribbon domain YABBY PF04690.8 EKG10728.1 - 0.0089 16.2 0.4 0.0089 16.2 0.3 1.9 2 0 0 2 2 2 1 YABBY protein HMG_box PF00505.14 EKG10728.1 - 0.029 14.6 0.5 0.16 12.2 0.1 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box Peptidase_MA_2 PF13485.1 EKG10728.1 - 0.04 13.9 0.2 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily Sulfotransfer_3 PF13469.1 EKG10729.1 - 5.5e-06 27.3 1.1 1e-05 26.5 0.8 1.5 1 1 0 1 1 1 1 Sulfotransferase family Arylsulfotran_2 PF14269.1 EKG10730.1 - 2.6e-56 190.9 3.4 4e-56 190.3 2.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EKG10730.1 - 2.1e-19 69.3 2.5 1.1e-17 63.7 1.7 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) dTDP_sugar_isom PF00908.12 EKG10730.1 - 0.027 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase MFS_1 PF07690.11 EKG10731.1 - 5.4e-18 64.8 10.5 5.4e-18 64.8 7.3 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EKG10731.1 - 0.00016 19.9 1.9 0.0003 19.0 1.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector R3H PF01424.17 EKG10732.1 - 2.3e-12 46.4 0.0 8.7e-12 44.5 0.0 2.1 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EKG10732.1 - 1.6e-10 40.6 0.4 3.3e-10 39.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain Chromo PF00385.19 EKG10732.1 - 5.5e-05 22.7 0.0 5.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain G-patch_2 PF12656.2 EKG10732.1 - 0.0031 17.3 0.2 0.0031 17.3 0.2 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site S-antigen PF05756.6 EKG10732.1 - 0.74 9.8 6.3 2.2 8.3 4.4 1.8 1 0 0 1 1 1 0 S-antigen protein DNA_pol_phi PF04931.8 EKG10732.1 - 9 3.9 23.1 15 3.1 16.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Peptidase_C54 PF03416.14 EKG10733.1 - 2e-93 312.5 0.0 2.5e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_M14 PF00246.19 EKG10733.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Zinc carboxypeptidase Histone PF00125.19 EKG10734.1 - 1.5e-17 63.5 0.3 3.3e-17 62.3 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EKG10734.1 - 0.00065 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EKG10734.1 - 0.0017 18.3 1.2 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKG10735.1 - 8.6e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKG10735.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 EKG10736.1 - 9.3e-09 34.9 0.7 1.3e-08 34.5 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EKG10736.1 - 9.3e-08 32.1 0.3 1.2e-07 31.8 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 EKG10737.1 - 1.5e-80 269.7 0.1 2e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EKG10737.1 - 7.8e-18 63.8 3.2 1.6e-17 62.9 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EKG10737.1 - 0.00029 20.0 4.6 0.00037 19.7 1.0 2.3 1 1 2 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EKG10737.1 - 0.0071 15.9 0.3 0.018 14.6 0.1 1.7 1 1 0 1 1 1 1 Biotin-lipoyl like CMV_1a PF12467.3 EKG10737.1 - 1.7 8.9 9.2 28 5.0 5.8 2.5 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Glyco_hydro_2_N PF02837.13 EKG10738.1 - 4.3e-26 91.4 0.1 1.1e-25 90.1 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EKG10738.1 - 1.1e-13 50.7 0.0 2.5e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EKG10738.1 - 2.8e-08 34.1 0.0 7.3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Treslin_N PF15292.1 EKG10738.1 - 0.022 12.6 0.1 0.03 12.2 0.0 1.1 1 0 0 1 1 1 0 Treslin N-terminus Sec7 PF01369.15 EKG10739.1 - 5.7e-39 133.7 0.0 1.6e-38 132.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EKG10739.1 - 7.6e-21 74.4 0.0 1e-19 70.8 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PP28 PF10252.4 EKG10740.1 - 4.4e-28 97.1 23.5 4.4e-28 97.1 16.3 3.3 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 HAD_2 PF13419.1 EKG10741.1 - 1.4e-29 103.5 0.0 1.7e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG10741.1 - 2.3e-05 23.9 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EKG10741.1 - 0.053 13.9 0.0 0.097 13.0 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HNH PF01844.18 EKG10742.1 - 0.00076 19.2 0.6 0.0014 18.4 0.4 1.4 1 0 0 1 1 1 1 HNH endonuclease C1_1 PF00130.17 EKG10742.1 - 0.14 11.8 1.3 0.35 10.6 0.9 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GSu_C4xC__C2xCH PF09698.5 EKG10742.1 - 1.9 8.7 5.6 3.8 7.7 0.4 2.4 2 0 0 2 2 2 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Pec_lyase_C PF00544.14 EKG10743.1 - 2.2e-18 66.4 0.6 3.9e-18 65.6 0.4 1.4 1 0 0 1 1 1 1 Pectate lyase Alpha-amylase PF00128.19 EKG10746.1 - 1.8e-69 234.5 0.8 2.7e-69 234.0 0.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EKG10746.1 - 3.5e-32 110.3 0.1 6.8e-32 109.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) zf-C2H2_4 PF13894.1 EKG10748.1 - 0.0024 18.1 11.2 0.2 12.0 1.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG10748.1 - 0.04 14.2 13.5 0.25 11.7 1.3 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Not3 PF04065.10 EKG10749.1 - 3.5e-100 334.0 25.4 5.4e-100 333.4 17.6 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EKG10749.1 - 4e-43 146.5 11.8 1.1e-42 145.0 8.2 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family NIT PF08376.5 EKG10749.1 - 0.0033 17.0 5.8 0.046 13.2 0.3 2.6 2 0 0 2 2 2 2 Nitrate and nitrite sensing DUF2373 PF10180.4 EKG10749.1 - 0.0057 16.1 2.8 0.014 14.9 1.9 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.8 EKG10749.1 - 0.011 15.6 7.4 0.15 12.0 0.3 3.1 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF641 PF04859.7 EKG10749.1 - 0.057 13.1 17.5 0.15 11.8 4.9 2.8 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) Poty_PP PF08440.5 EKG10749.1 - 0.19 10.7 5.6 0.047 12.7 0.4 2.0 2 0 0 2 2 2 0 Potyviridae polyprotein Tyr_Deacylase PF02580.11 EKG10750.1 - 2.8e-45 153.8 0.1 3.7e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase RNA_pol_Rpb1_5 PF04998.12 EKG10751.1 - 3.7e-90 301.9 0.5 9.5e-90 300.6 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EKG10751.1 - 6.6e-83 278.7 0.0 1.1e-82 278.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EKG10751.1 - 3.8e-65 218.8 0.0 7.1e-65 217.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EKG10751.1 - 1.6e-32 112.4 0.0 3.9e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EKG10751.1 - 1.8e-28 98.3 0.0 6.3e-28 96.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-tcix PF14952.1 EKG10751.1 - 0.014 14.6 3.2 0.046 13.0 2.2 1.9 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding FHA PF00498.21 EKG10752.1 - 1.6e-11 44.1 0.0 3.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Alpha_GJ PF03229.8 EKG10752.1 - 0.076 13.3 0.3 0.076 13.3 0.2 3.6 4 0 0 4 4 4 0 Alphavirus glycoprotein J NUP50 PF08911.6 EKG10752.1 - 6.1 7.2 7.1 0.34 11.3 0.4 2.3 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) F_bP_aldolase PF01116.15 EKG10753.1 - 4.4e-86 288.5 0.0 4.9e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.1 EKG10754.1 - 1.1e-34 119.0 0.1 1e-24 86.9 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Abhydrolase_6 PF12697.2 EKG10755.1 - 8.7e-10 38.8 0.9 1.2e-09 38.4 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG10755.1 - 8.2e-08 32.1 0.0 1.6e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG10755.1 - 7.2e-05 22.0 0.0 0.0096 15.1 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 EKG10755.1 - 0.01 15.3 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 EKG10755.1 - 0.023 14.4 0.0 0.65 9.6 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PLDc PF00614.17 EKG10756.1 - 1.5e-14 53.2 1.7 2.8e-06 26.9 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EKG10756.1 - 1.1e-12 47.7 0.0 3e-08 33.4 0.0 2.8 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EKG10756.1 - 1.1e-09 38.0 0.0 4.7e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 PX domain PAN_4 PF14295.1 EKG10757.1 - 2.2e-11 43.2 10.6 2.9e-09 36.4 2.3 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.6 EKG10757.1 - 0.079 12.8 11.9 1.1 9.1 1.5 2.9 2 1 0 2 2 2 0 PAN-like domain Abhydrolase_6 PF12697.2 EKG10760.1 - 0.019 14.8 0.1 0.04 13.8 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4202 PF13875.1 EKG10762.1 - 1.6e-80 269.0 0.1 1.8e-80 268.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) ClpS PF02617.12 EKG10762.1 - 0.05 13.3 0.0 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS DUF2434 PF10361.4 EKG10763.1 - 1.1e-123 412.0 8.5 1.4e-123 411.7 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) DUF791 PF05631.9 EKG10763.1 - 0.018 13.7 0.5 0.029 13.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF791) Cation_ATPase_C PF00689.16 EKG10763.1 - 3.8 6.9 10.9 0.059 12.9 1.5 2.2 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Fungal_trans PF04082.13 EKG10764.1 - 1.6e-09 37.0 0.1 2.1e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.22 EKG10766.1 - 4.5e-58 192.9 4.1 1.4e-23 82.3 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein MAM33 PF02330.11 EKG10767.1 - 4.2e-33 114.8 8.7 4.7e-24 85.2 0.2 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein DUF2962 PF11176.3 EKG10768.1 - 2.9e-46 156.8 0.7 3.3e-46 156.6 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) XPG_I PF00867.13 EKG10769.1 - 2.4e-25 88.4 0.2 5.6e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EKG10769.1 - 6.1e-22 77.8 0.0 1.2e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EKG10769.1 - 0.0083 15.6 1.5 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.15 EKG10769.1 - 0.009 16.2 0.0 0.029 14.6 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold YccV-like PF08755.6 EKG10770.1 - 7.8e-25 86.7 0.0 2e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EKG10770.1 - 8.3e-16 57.8 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EKG10770.1 - 2.3e-11 43.2 1.9 5.6e-11 41.9 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG10770.1 - 4.4e-08 32.5 0.6 1.1e-07 31.3 0.4 1.7 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EKG10770.1 - 0.12 12.3 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 PRANC domain SSF PF00474.12 EKG10771.1 - 7.3e-19 67.6 28.8 1.2e-18 66.9 20.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family FAD_binding_3 PF01494.14 EKG10772.1 - 5.8e-08 32.1 2.9 0.00096 18.2 0.4 2.8 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 EKG10772.1 - 0.00016 22.0 0.6 0.00058 20.2 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG10772.1 - 0.0003 19.8 3.3 0.021 13.7 0.1 2.6 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG10772.1 - 0.0022 17.9 0.1 0.022 14.6 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG10772.1 - 0.0073 16.3 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EKG10772.1 - 0.025 13.6 0.3 0.049 12.7 0.2 1.7 1 1 1 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG10772.1 - 0.03 12.8 0.3 0.078 11.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein PQ-loop PF04193.9 EKG10773.1 - 4.2e-22 77.4 15.5 6.2e-12 44.8 0.3 3.0 3 1 0 3 3 3 2 PQ loop repeat Oxidored_q4 PF00507.14 EKG10773.1 - 0.005 16.6 1.6 0.47 10.3 0.0 2.7 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF1129 PF06570.6 EKG10773.1 - 0.029 13.6 0.5 0.07 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) YesK PF14150.1 EKG10773.1 - 0.033 14.2 1.8 0.033 14.2 1.3 3.9 4 1 1 5 5 5 0 YesK-like protein DUF1440 PF07274.7 EKG10773.1 - 0.1 12.5 3.4 0.16 11.9 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) DUF1469 PF07332.6 EKG10773.1 - 2 8.1 16.2 1.1 8.9 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) DUF2207 PF09972.4 EKG10773.1 - 5.3 5.5 6.8 4.2 5.8 0.6 2.3 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Wyosine_form PF08608.7 EKG10774.1 - 4.6e-24 84.2 0.0 1.5e-23 82.6 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 EKG10774.1 - 5.7e-24 85.1 0.1 1.3e-23 83.9 0.1 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 EKG10774.1 - 5.9e-11 42.5 0.1 2.3e-09 37.3 0.1 2.4 1 1 0 1 1 1 1 Flavodoxin Spc97_Spc98 PF04130.8 EKG10775.1 - 2.1e-70 237.5 0.0 2.8e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3762 PF12591.3 EKG10775.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) FAD_binding_4 PF01565.18 EKG10776.1 - 2.2e-29 101.7 0.2 3.5e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FtsX PF02687.16 EKG10777.1 - 0.091 12.5 0.1 0.091 12.5 0.1 2.7 3 0 0 3 3 3 0 FtsX-like permease family DAO PF01266.19 EKG10778.1 - 2.4e-09 36.5 0.6 3e-09 36.2 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG10778.1 - 4.8e-09 36.1 0.2 1.3e-08 34.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG10778.1 - 3e-08 33.7 0.2 3.5e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG10778.1 - 3.9e-08 32.7 0.1 4.3e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EKG10778.1 - 8.6e-08 31.4 0.4 1.1e-07 31.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EKG10778.1 - 1.6e-05 25.2 0.7 9.3e-05 22.7 0.3 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG10778.1 - 3.3e-05 23.0 0.1 4.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EKG10778.1 - 4.3e-05 22.1 0.1 5.9e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EKG10778.1 - 0.00015 20.5 0.3 0.00018 20.2 0.2 1.1 1 0 0 1 1 1 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EKG10778.1 - 0.00024 20.7 0.2 0.00035 20.1 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EKG10778.1 - 0.00048 19.0 0.4 0.00058 18.8 0.3 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EKG10778.1 - 0.0012 18.0 0.1 0.0012 18.0 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EKG10778.1 - 0.0026 17.7 0.2 0.0037 17.2 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Amino_oxidase PF01593.19 EKG10778.1 - 0.004 16.3 0.1 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ApbA PF02558.11 EKG10778.1 - 0.0045 16.4 0.4 0.0062 15.9 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EKG10778.1 - 0.0099 15.5 0.2 0.012 15.2 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EKG10778.1 - 0.011 15.7 0.1 0.012 15.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EKG10778.1 - 0.059 12.7 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EKG10778.1 - 0.092 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Strep_67kDa_ant PF06100.6 EKG10778.1 - 0.11 10.8 0.1 0.14 10.4 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Methyltransf_18 PF12847.2 EKG10778.1 - 0.12 13.0 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_7 PF13241.1 EKG10778.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding Cupin_2 PF07883.6 EKG10779.1 - 1.3e-10 40.6 0.0 2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EKG10779.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EKG10779.1 - 0.066 12.6 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Cupin Glyco_hydro_2_C PF02836.12 EKG10780.1 - 0.0002 20.3 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Alpha_L_fucos PF01120.12 EKG10781.1 - 5.8e-78 262.2 2.3 8e-78 261.7 1.6 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase RRM_6 PF14259.1 EKG10783.1 - 6.4e-05 22.8 0.1 0.00026 20.8 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG10783.1 - 0.00015 21.3 0.0 0.013 15.1 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG10783.1 - 0.034 14.0 0.0 0.085 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3166 PF11365.3 EKG10783.1 - 2 8.9 7.6 0.5 10.8 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) Oligomerisation PF02410.10 EKG10784.1 - 0.00025 21.0 0.0 0.0056 16.6 0.0 2.6 1 1 0 1 1 1 1 Oligomerisation domain PPR_3 PF13812.1 EKG10784.1 - 0.00075 19.5 0.0 18 5.9 0.0 3.9 3 0 0 3 3 3 3 Pentatricopeptide repeat domain NMD3 PF04981.8 EKG10785.1 - 9.7e-74 247.4 4.3 1.4e-73 246.9 3.0 1.2 1 0 0 1 1 1 1 NMD3 family HypA PF01155.14 EKG10785.1 - 4.8 6.8 6.1 30 4.3 0.0 2.7 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Pex2_Pex12 PF04757.9 EKG10786.1 - 3.9e-53 180.2 1.6 5.5e-53 179.7 1.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EKG10786.1 - 0.0077 16.2 1.5 0.0077 16.2 1.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKG10786.1 - 0.014 15.2 3.8 0.03 14.2 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cyclase PF04199.8 EKG10789.1 - 3.6e-16 59.3 0.1 6e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase DUF22 PF01629.11 EKG10789.1 - 0.09 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF22 F-box PF00646.28 EKG10793.1 - 8e-08 31.7 1.0 2.7e-07 30.0 0.7 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKG10793.1 - 1.8e-06 27.5 1.3 1.8e-06 27.5 0.9 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EKG10793.1 - 0.0023 17.6 0.1 0.0023 17.6 0.1 2.1 3 0 0 3 3 3 1 F-box-like domain Sel1 PF08238.7 EKG10794.1 - 1.6e-22 79.3 17.8 4.6e-07 30.2 0.0 7.1 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 EKG10794.1 - 0.0063 16.0 3.6 0.092 12.3 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF4244 PF14029.1 EKG10794.1 - 0.12 11.4 0.5 0.94 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) TPR_2 PF07719.12 EKG10794.1 - 0.21 11.5 2.4 18 5.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.8 EKG10795.1 - 9.9e-68 226.6 0.0 1.3e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EKG10795.1 - 7 4.4 27.3 9.1 4.0 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family Lgl_C PF08596.5 EKG10796.1 - 1.4e-121 405.7 0.0 2e-121 405.1 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EKG10796.1 - 1.7e-07 30.8 0.0 0.014 15.2 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Asp PF00026.18 EKG10797.1 - 5.3e-23 81.7 0.0 7.1e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG10797.1 - 0.00044 20.7 1.0 0.86 10.1 0.4 3.3 2 1 0 2 2 2 2 Aspartyl protease Epimerase PF01370.16 EKG10799.1 - 1.5e-06 27.8 0.0 7.7e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EKG10799.1 - 0.00015 22.0 0.0 0.00033 20.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EKG10799.1 - 0.016 14.4 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family JAB PF01398.16 EKG10800.1 - 6.4e-15 54.9 0.0 1.1e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EKG10800.1 - 1.3e-10 41.2 1.0 2.3e-10 40.4 0.7 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EKG10800.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PhoU PF01895.14 EKG10801.1 - 0.35 11.3 2.5 1.5 9.3 0.1 2.8 3 0 0 3 3 3 0 PhoU domain Ribosomal_L31 PF01197.13 EKG10802.1 - 0.001 18.9 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L31 Polyketide_cyc PF03364.15 EKG10802.1 - 0.018 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Flavin_Reduct PF01613.13 EKG10803.1 - 1.8e-16 60.3 0.1 3.2e-16 59.5 0.0 1.5 1 1 0 1 1 1 1 Flavin reductase like domain Med11 PF10280.4 EKG10804.1 - 1.5e-15 57.2 0.0 5.7e-15 55.3 0.0 1.8 1 1 0 1 1 1 1 Mediator complex protein Amidohydro_3 PF07969.6 EKG10804.1 - 0.064 12.4 0.1 0.093 11.9 0.1 1.4 1 1 0 1 1 1 0 Amidohydrolase family WD40 PF00400.27 EKG10805.1 - 5.7e-57 187.6 26.7 1.5e-10 40.5 1.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EKG10805.1 - 5.7e-45 152.8 0.3 8.5e-45 152.3 0.2 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit eIF2A PF08662.6 EKG10805.1 - 4.3e-05 23.3 0.1 0.0002 21.1 0.0 2.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EKG10805.1 - 6e-05 21.3 3.7 0.26 9.3 0.0 3.5 2 1 1 4 4 4 3 Nucleoporin Nup120/160 LisH PF08513.6 EKG10805.1 - 0.002 17.8 1.2 0.0029 17.2 0.0 1.9 2 0 0 2 2 2 1 LisH Nucleoporin_N PF08801.6 EKG10805.1 - 0.0095 14.7 0.7 1.5 7.4 0.0 3.5 1 1 2 4 4 4 2 Nup133 N terminal like PTR2 PF00854.16 EKG10806.1 - 2.4e-44 151.6 9.5 6e-44 150.3 6.6 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EKG10806.1 - 6.3e-09 35.0 14.7 1.9e-08 33.3 9.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 EKG10806.1 - 9.5 5.4 7.8 10 5.3 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function DUF21 GTP_EFTU PF00009.22 EKG10807.1 - 4.1e-39 133.9 1.9 3.2e-38 131.0 1.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EKG10807.1 - 1.6e-24 85.9 0.1 4.8e-24 84.3 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EKG10807.1 - 7.2e-14 51.6 2.0 1.4e-06 28.3 0.1 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKG10807.1 - 1.1e-07 31.8 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 EKG10807.1 - 3.4e-06 26.6 0.0 1e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 EKG10807.1 - 3e-05 24.5 0.0 6.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EKG10807.1 - 0.00011 21.7 1.0 0.023 14.3 0.1 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FeoB_N PF02421.13 EKG10807.1 - 0.00025 20.3 0.1 0.00084 18.6 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EKG10807.1 - 0.00044 19.7 0.3 0.0014 18.1 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EKG10807.1 - 0.0015 17.7 0.0 0.0038 16.4 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EKG10807.1 - 0.0018 17.5 0.0 0.0036 16.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family EAF PF09816.4 EKG10807.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor Dynamin_N PF00350.18 EKG10807.1 - 0.32 10.8 4.2 8.2 6.2 0.0 3.2 2 1 1 3 3 3 0 Dynamin family TATR PF03430.8 EKG10807.1 - 1.3 7.5 2.5 2.5 6.6 1.8 1.4 1 0 0 1 1 1 0 Trans-activating transcriptional regulator UNC-50 PF05216.8 EKG10808.1 - 6e-83 277.6 8.4 7.5e-83 277.2 5.8 1.0 1 0 0 1 1 1 1 UNC-50 family Suf PF05843.9 EKG10809.1 - 6.9e-85 285.1 8.3 3.7e-83 279.5 0.0 3.6 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EKG10809.1 - 6.9e-07 29.7 0.2 0.00014 22.4 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKG10809.1 - 0.00016 22.0 0.6 0.17 12.6 0.1 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG10809.1 - 0.00019 21.7 0.0 0.036 14.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat NAM PF02365.10 EKG10809.1 - 0.006 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 No apical meristem (NAM) protein HAT PF02184.11 EKG10809.1 - 0.036 13.8 1.5 0.13 12.0 0.5 2.3 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat CENP-B_dimeris PF09026.5 EKG10809.1 - 3.1 8.1 6.8 0.53 10.5 0.9 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Piwi PF02171.12 EKG10810.1 - 5.5e-74 248.8 0.0 7.5e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EKG10810.1 - 1.7e-15 56.4 0.2 3.1e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EKG10810.1 - 1.8e-15 56.0 0.5 4.4e-15 54.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) Methyltransf_2 PF00891.13 EKG10811.1 - 6.1e-26 91.0 0.0 8.3e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EKG10811.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EKG10812.1 - 1.9e-21 76.4 0.0 3.2e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10812.1 - 2.3e-09 37.5 0.0 4.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10812.1 - 6.9e-09 36.2 0.0 2.6e-07 31.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10812.1 - 1.2e-08 34.6 0.0 2.9e-07 30.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG10812.1 - 2.5e-08 34.3 0.0 2.2e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG10812.1 - 6.7e-05 23.1 0.0 0.00024 21.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG10812.1 - 7.9e-05 22.0 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EKG10812.1 - 0.0003 19.8 0.0 0.00068 18.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EKG10812.1 - 0.00047 19.3 0.0 0.0015 17.7 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EKG10812.1 - 0.0012 18.9 0.0 0.003 17.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EKG10812.1 - 0.0039 16.6 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EKG10812.1 - 0.034 14.1 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF938 PF06080.7 EKG10812.1 - 0.049 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Fzo_mitofusin PF04799.8 EKG10813.1 - 0.03 13.7 0.7 0.054 12.8 0.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF4515 PF14988.1 EKG10813.1 - 0.054 13.1 5.5 0.091 12.4 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DivIC PF04977.10 EKG10813.1 - 0.77 9.2 4.1 1.7 8.2 2.8 1.5 1 0 0 1 1 1 0 Septum formation initiator CTP_transf_2 PF01467.21 EKG10816.1 - 0.011 15.8 0.0 0.3 11.1 0.0 2.7 2 1 0 2 2 2 0 Cytidylyltransferase Meth_synt_2 PF01717.13 EKG10817.1 - 2.2e-142 473.7 0.0 1.6e-137 457.8 0.0 2.5 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EKG10817.1 - 9.7e-126 419.2 0.0 1.6e-113 379.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EKG10817.1 - 0.045 12.6 0.0 1.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) zf-RING_2 PF13639.1 EKG10818.1 - 1.1e-08 34.8 6.3 4.8e-08 32.6 4.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKG10818.1 - 1.2e-06 28.5 1.0 3e-06 27.2 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EKG10818.1 - 4.1e-06 26.4 5.4 9.2e-06 25.2 3.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKG10818.1 - 8.5e-06 25.5 2.6 1.7e-05 24.5 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EKG10818.1 - 2.1e-05 24.2 6.3 2.1e-05 24.2 4.4 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EKG10818.1 - 8.1e-05 22.1 4.0 0.00023 20.7 2.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG10818.1 - 0.00066 19.6 8.3 0.026 14.5 5.7 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG10818.1 - 0.0019 17.9 7.0 0.0048 16.5 4.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EKG10818.1 - 0.082 12.5 6.5 0.29 10.8 4.5 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EKG10818.1 - 0.35 10.4 3.2 0.71 9.4 2.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Kelch_4 PF13418.1 EKG10819.1 - 0.00023 20.8 7.5 1.4 8.7 0.1 5.0 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EKG10819.1 - 0.0091 15.9 0.3 0.29 11.1 0.0 3.5 4 0 0 4 4 4 1 Kelch motif GST_N_3 PF13417.1 EKG10820.1 - 8.3e-14 51.5 0.1 2.1e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG10820.1 - 3.4e-13 49.5 0.0 1.4e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EKG10820.1 - 3e-12 46.3 0.1 4.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG10820.1 - 4.1e-10 39.5 0.0 1.2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG10820.1 - 1.4e-07 31.3 0.2 2.3e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG10820.1 - 1.9e-06 28.3 0.4 3e-06 27.6 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EKG10820.1 - 0.031 14.6 0.0 0.087 13.2 0.0 1.7 2 0 0 2 2 2 0 MetRS-N binding domain Cupin_1 PF00190.17 EKG10822.1 - 9.5e-24 83.4 0.0 2.4e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EKG10822.1 - 3.9e-22 77.5 0.2 7.8e-11 41.3 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EKG10822.1 - 2.4e-08 33.2 0.0 0.0082 15.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EKG10822.1 - 0.00055 19.6 0.1 0.0028 17.3 0.0 2.0 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EKG10822.1 - 0.00086 18.9 0.0 0.023 14.2 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 EKG10822.1 - 0.031 13.6 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase DUF1971 PF09313.6 EKG10822.1 - 0.064 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) 2OG-FeII_Oxy_5 PF13759.1 EKG10822.1 - 0.089 13.0 0.1 21 5.4 0.0 3.6 2 2 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase Cupin_4 PF08007.7 EKG10822.1 - 0.13 11.4 0.0 0.6 9.2 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Peptidase_M15_2 PF05951.8 EKG10822.1 - 0.16 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) DUF3405 PF11885.3 EKG10823.1 - 8.4e-206 683.9 10.0 1.5e-205 683.1 3.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3405) Rtt106 PF08512.7 EKG10826.1 - 2.4e-27 94.7 0.1 4.1e-27 94.0 0.1 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like TFIIA PF03153.8 EKG10826.1 - 0.002 18.1 3.4 0.002 18.1 2.3 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 EKG10826.1 - 4 7.0 13.5 6.7 6.3 9.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Kelch_5 PF13854.1 EKG10828.1 - 2.2e-13 49.8 10.7 2e-09 37.1 0.2 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 EKG10828.1 - 3.9e-07 29.7 21.2 0.027 14.2 0.4 6.7 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EKG10828.1 - 0.00011 22.3 19.8 0.0095 16.0 0.5 6.3 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EKG10828.1 - 0.00039 20.4 19.6 1.1 9.5 0.0 6.0 4 1 1 5 5 5 2 Kelch motif SKG6 PF08693.5 EKG10828.1 - 0.00046 19.4 0.6 0.00093 18.4 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EKG10828.1 - 0.0014 16.9 0.0 0.002 16.4 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EKG10828.1 - 0.0068 15.2 0.1 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Kelch_1 PF01344.20 EKG10828.1 - 0.013 14.9 14.1 1.7 8.2 0.2 6.3 6 0 0 6 6 6 0 Kelch motif EphA2_TM PF14575.1 EKG10828.1 - 0.037 14.4 0.0 0.077 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Beta-APP PF03494.8 EKG10828.1 - 1 8.8 3.4 2.7 7.5 2.4 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) PAT1 PF09770.4 EKG10828.1 - 5.4 5.1 14.2 7.3 4.6 9.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aa_trans PF01490.13 EKG10829.1 - 4.6e-77 259.2 28.0 5.6e-77 258.9 19.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CASP_C PF08172.7 EKG10830.1 - 0.0018 17.3 6.4 0.046 12.7 0.7 2.5 1 1 1 2 2 2 2 CASP C terminal bZIP_2 PF07716.10 EKG10830.1 - 0.0032 17.2 12.3 0.28 11.0 0.0 4.8 3 1 0 4 4 4 2 Basic region leucine zipper Cortex-I_coil PF09304.5 EKG10830.1 - 0.005 16.8 13.7 0.0092 16.0 4.8 2.4 1 1 1 2 2 2 1 Cortexillin I, coiled coil APG6 PF04111.7 EKG10830.1 - 0.011 14.7 10.9 0.016 14.2 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2353 PF09789.4 EKG10830.1 - 0.033 13.4 7.9 0.87 8.7 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) ERM PF00769.14 EKG10830.1 - 0.042 13.3 21.2 0.12 11.8 13.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.7 EKG10830.1 - 0.069 12.9 2.9 0.17 11.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GLTSCR1 PF15249.1 EKG10830.1 - 0.1 12.7 4.1 0.75 9.9 0.2 2.4 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region Reo_sigmaC PF04582.7 EKG10830.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.3 1 1 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 EKG10830.1 - 0.19 10.9 11.9 2.2 7.4 5.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMCO5 PF14992.1 EKG10830.1 - 0.3 10.1 8.1 0.41 9.7 5.6 1.1 1 0 0 1 1 1 0 TMCO5 family DUF972 PF06156.8 EKG10830.1 - 0.3 11.4 6.8 0.45 10.8 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4201 PF13870.1 EKG10830.1 - 0.34 10.3 12.4 0.38 10.1 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) SPX PF03105.14 EKG10830.1 - 0.34 10.6 5.8 15 5.2 4.0 2.2 1 1 0 1 1 1 0 SPX domain DUF724 PF05266.9 EKG10830.1 - 0.47 10.0 8.4 1.8 8.1 5.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.4 EKG10830.1 - 0.62 9.9 11.8 0.092 12.6 2.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 EKG10830.1 - 0.75 9.3 15.5 0.24 10.9 7.0 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Jnk-SapK_ap_N PF09744.4 EKG10830.1 - 0.97 9.4 6.8 1.5 8.7 4.3 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 FAM92 PF06730.6 EKG10830.1 - 1.4 8.1 7.1 0.83 8.9 1.7 2.1 1 1 1 2 2 2 0 FAM92 protein IncA PF04156.9 EKG10830.1 - 1.6 8.3 14.5 30 4.1 10.1 2.2 1 1 0 1 1 1 0 IncA protein Ax_dynein_light PF10211.4 EKG10830.1 - 2.1 8.1 10.8 0.094 12.5 1.2 2.5 1 1 2 3 3 3 0 Axonemal dynein light chain TMF_DNA_bd PF12329.3 EKG10830.1 - 2.2 8.1 10.2 0.31 10.8 0.4 2.9 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EKG10830.1 - 2.2 7.8 16.3 0.15 11.6 1.5 3.6 1 1 2 3 3 3 0 Septum formation initiator V_ATPase_I PF01496.14 EKG10830.1 - 2.2 6.0 4.1 2.8 5.6 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EKG10830.1 - 2.7 8.3 10.0 4.5 7.6 1.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF904) ADIP PF11559.3 EKG10830.1 - 2.8 7.8 14.1 0.71 9.7 2.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EKG10830.1 - 3.8 7.2 11.9 4.4 7.0 0.1 4.4 3 2 2 5 5 5 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.3 EKG10830.1 - 7.4 6.3 12.4 7.3 6.3 1.1 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.3 EKG10830.1 - 7.6 3.7 16.4 9.7 3.3 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Kelch_3 PF13415.1 EKG10831.1 - 4e-05 23.6 4.6 0.022 14.9 0.1 4.3 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 EKG10831.1 - 0.00019 21.3 0.0 0.00019 21.3 0.0 5.7 6 0 0 6 6 6 1 Kelch motif SKG6 PF08693.5 EKG10831.1 - 0.012 14.9 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EKG10831.1 - 0.058 12.9 11.1 4.8 6.8 0.0 5.0 5 0 0 5 5 5 0 Kelch motif PDGLE PF13190.1 EKG10831.1 - 0.1 12.3 1.1 0.21 11.2 0.8 1.5 1 0 0 1 1 1 0 PDGLE domain Kelch_6 PF13964.1 EKG10831.1 - 0.11 12.7 19.7 1.3 9.3 0.1 5.6 4 2 1 5 5 5 0 Kelch motif UPF0242 PF06785.6 EKG10833.1 - 0.0016 17.1 2.8 0.002 16.8 2.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) Spc7 PF08317.6 EKG10833.1 - 0.027 13.1 4.0 0.033 12.8 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Thioredoxin_8 PF13905.1 EKG10833.1 - 0.035 14.2 1.1 2.4 8.3 0.5 2.9 1 1 0 2 2 2 0 Thioredoxin-like ACCA PF03255.9 EKG10833.1 - 0.065 12.7 3.7 0.13 11.7 2.5 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GNT-I PF03071.10 EKG10833.1 - 0.065 11.7 0.4 0.085 11.3 0.3 1.1 1 0 0 1 1 1 0 GNT-I family Vps51 PF08700.6 EKG10833.1 - 0.17 11.7 5.0 8.7 6.2 0.3 2.2 1 1 0 1 1 1 0 Vps51/Vps67 Tup_N PF08581.5 EKG10833.1 - 0.2 11.8 4.6 0.37 11.0 3.2 1.5 1 0 0 1 1 1 0 Tup N-terminal DUF1090 PF06476.7 EKG10833.1 - 0.24 11.0 7.5 0.42 10.2 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) TMPIT PF07851.8 EKG10833.1 - 0.31 10.0 2.8 0.43 9.6 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.8 EKG10833.1 - 0.33 11.3 5.7 0.61 10.4 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EKG10833.1 - 0.47 10.0 6.8 1.3 8.6 4.7 1.7 1 1 0 1 1 1 0 IncA protein Methyltransf_23 PF13489.1 EKG10834.1 - 1.5e-22 80.0 0.0 2.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG10834.1 - 1.2e-08 35.4 0.0 1.6e-07 31.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG10834.1 - 6.8e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG10834.1 - 1.1e-07 31.6 0.0 1.6e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG10834.1 - 0.00059 20.2 0.0 0.0031 17.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG10834.1 - 0.00068 19.9 0.0 0.002 18.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG10834.1 - 0.013 15.5 0.0 0.047 13.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EKG10834.1 - 0.042 12.9 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EKG10834.1 - 0.046 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_4 PF01565.18 EKG10837.1 - 5.1e-23 81.0 3.5 1e-22 80.0 2.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG10837.1 - 4e-08 33.0 0.3 1e-07 31.7 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like adh_short PF00106.20 EKG10838.1 - 2.5e-21 76.3 0.1 3.8e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10838.1 - 1.1e-19 71.2 0.0 2.5e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG10838.1 - 7.1e-11 42.1 0.1 1e-10 41.6 0.1 1.2 1 0 0 1 1 1 1 KR domain But2 PF09792.4 EKG10839.1 - 2.1e-29 102.1 1.8 2.6e-29 101.8 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain GFA PF04828.9 EKG10840.1 - 8.4e-21 73.7 0.1 8.4e-21 73.7 0.1 2.1 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Dabb PF07876.7 EKG10840.1 - 1.6e-19 70.1 0.0 2.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Abhydrolase_3 PF07859.8 EKG10841.1 - 1.8e-46 158.3 0.0 2.3e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG10841.1 - 4.1e-07 29.1 0.6 9.9e-07 27.8 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EKG10841.1 - 9.6e-05 22.3 0.5 0.00018 21.4 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADH_N PF08240.7 EKG10842.1 - 8.1e-05 22.3 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Bac_luciferase PF00296.15 EKG10843.1 - 6.8e-52 176.5 0.0 8.3e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 EKG10846.1 - 7.7e-27 93.9 22.1 7.7e-27 93.9 15.3 3.1 2 1 0 3 3 3 1 Major Facilitator Superfamily DAO PF01266.19 EKG10848.1 - 9.3e-35 120.1 0.3 1.1e-34 119.9 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG10848.1 - 0.0083 15.9 0.2 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG10848.1 - 0.042 13.7 0.1 0.069 13.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG10848.1 - 0.047 13.7 0.0 7.2 6.6 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG10848.1 - 0.066 13.2 0.8 0.47 10.5 0.2 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 EKG10849.1 - 1.3e-28 99.7 20.5 1.3e-28 99.7 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG10849.1 - 3.5e-10 39.0 9.8 3.5e-10 39.0 6.8 3.2 2 1 0 3 3 3 1 Sugar (and other) transporter DUF2953 PF11167.3 EKG10849.1 - 0.11 12.3 0.4 0.11 12.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) IU_nuc_hydro PF01156.14 EKG10850.1 - 3e-46 158.0 0.0 3.6e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase BolA PF01722.13 EKG10853.1 - 5.8e-16 58.2 0.0 6.9e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein FpoO PF10621.4 EKG10853.1 - 0.13 12.2 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO SH3_9 PF14604.1 EKG10854.1 - 5.4e-06 25.9 0.6 1.1e-05 24.8 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG10854.1 - 0.021 14.1 0.7 0.039 13.3 0.5 1.5 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.12 EKG10854.1 - 0.075 12.5 0.4 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Variant SH3 domain HypA PF01155.14 EKG10854.1 - 0.38 10.4 8.5 3.8 7.2 0.5 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Amidase PF01425.16 EKG10855.1 - 5.2e-54 183.7 0.0 1.8e-51 175.3 0.0 2.1 2 0 0 2 2 2 2 Amidase ICMT PF04140.9 EKG10856.1 - 1.3e-29 102.2 0.3 2.6e-29 101.2 0.2 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EKG10856.1 - 2.6e-16 59.6 2.0 2.6e-16 59.6 1.4 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EKG10856.1 - 3.8e-06 26.3 1.7 5.6e-06 25.8 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EKG10856.1 - 0.0075 14.8 2.8 0.0087 14.6 1.9 1.3 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF423 PF04241.10 EKG10856.1 - 0.016 15.1 0.9 0.016 15.1 0.6 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF423) TrbL PF04610.9 EKG10856.1 - 0.026 14.2 0.3 0.026 14.2 0.2 1.9 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Hexapep PF00132.19 EKG10857.1 - 1.2e-15 56.1 7.4 1.3e-10 40.3 1.4 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKG10857.1 - 1.1e-14 53.7 3.9 1.8e-11 43.4 0.6 3.3 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EKG10857.1 - 2.8e-10 40.0 0.2 5.3e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Acetyltransf_11 PF13720.1 EKG10857.1 - 0.086 13.0 1.3 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 p450 PF00067.17 EKG10859.1 - 3.1e-43 147.9 0.0 9.4e-34 116.7 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF221 PF02714.10 EKG10860.1 - 7.6e-92 307.6 15.3 9.6e-92 307.2 10.6 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4463 PF14703.1 EKG10860.1 - 5.7e-18 65.2 0.5 1.3e-17 64.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 EKG10860.1 - 9e-10 38.3 1.5 3.5e-09 36.3 1.1 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PMEI PF04043.10 EKG10861.1 - 0.00066 19.6 0.8 0.0027 17.6 0.6 2.1 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor Kinetochor_Ybp2 PF08568.5 EKG10861.1 - 0.0073 14.6 0.1 0.044 12.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin HEAT PF02985.17 EKG10861.1 - 0.056 13.5 4.4 13 6.1 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.1 EKG10862.1 - 1e-07 32.1 1.8 0.013 15.7 0.0 5.8 4 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EKG10862.1 - 6.5e-07 28.9 0.9 3.6 7.9 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EKG10862.1 - 0.0016 18.8 3.8 0.69 10.4 0.0 5.0 4 0 0 4 4 4 1 HEAT-like repeat DUF3268 PF11672.3 EKG10862.1 - 0.02 14.9 0.1 5.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3268) DUF4208 PF13907.1 EKG10862.1 - 0.32 11.2 2.6 29 4.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) Lectin_leg-like PF03388.8 EKG10863.1 - 4.2e-69 232.1 0.0 5.8e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EKG10863.1 - 0.00097 18.5 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.5 EKG10863.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.10 EKG10864.1 - 2.5e-24 84.3 2.3 2.9e-24 84.1 1.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.3 EKG10864.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) DUF4372 PF14294.1 EKG10864.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4372) Endonuclease_NS PF01223.18 EKG10865.1 - 2.8e-62 210.0 0.0 3.5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease CBFD_NFYB_HMF PF00808.18 EKG10866.1 - 1.4e-15 57.0 2.7 2e-15 56.5 1.9 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKG10866.1 - 0.00086 19.3 0.9 0.0013 18.8 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mt_ATP-synt_B PF05405.9 EKG10866.1 - 0.038 13.4 0.1 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-C3HC4_2 PF13923.1 EKG10867.1 - 1.3e-08 34.6 16.1 3.1e-05 23.8 4.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG10867.1 - 8.2e-07 28.6 13.1 1.8e-05 24.2 3.1 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG10867.1 - 1.5e-06 27.8 12.9 0.00025 20.8 3.5 2.5 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EKG10867.1 - 4.1e-05 23.2 16.2 4.4e-05 23.1 4.0 3.0 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EKG10867.1 - 5.6e-05 22.7 2.3 5.6e-05 22.7 1.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EKG10867.1 - 0.00074 19.1 2.5 0.00074 19.1 1.8 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EKG10867.1 - 0.0079 15.6 0.1 0.0079 15.6 0.1 4.1 4 2 0 4 4 4 1 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 EKG10867.1 - 0.012 15.4 14.7 0.039 13.8 3.3 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 EKG10867.1 - 0.023 14.5 9.9 0.059 13.2 2.4 2.8 2 1 0 2 2 2 0 FYVE zinc finger OmpH PF03938.9 EKG10867.1 - 0.031 14.2 0.3 0.049 13.5 0.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) E6 PF00518.12 EKG10867.1 - 0.2 11.9 0.1 0.2 11.9 0.1 3.0 2 2 0 3 3 3 0 Early Protein (E6) Rtf2 PF04641.7 EKG10867.1 - 3.8 6.6 21.4 0.026 13.7 2.7 3.2 2 2 0 2 2 2 0 Rtf2 RING-finger Acyltransferase PF01553.16 EKG10868.1 - 1.9e-09 37.0 0.0 4.1e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase SCA7 PF08313.7 EKG10869.1 - 3.1e-34 116.4 0.6 3.1e-34 116.4 0.4 2.4 2 0 0 2 2 2 1 SCA7, zinc-binding domain WAC_Acf1_DNA_bd PF10537.4 EKG10870.1 - 2e-29 101.7 0.0 6.5e-29 100.0 0.0 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EKG10870.1 - 8.8e-15 54.2 0.7 1.4e-14 53.5 0.5 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EKG10870.1 - 4.8e-07 29.4 0.5 4.8e-07 29.4 0.4 2.6 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EKG10870.1 - 0.0001 22.0 0.5 0.00044 19.9 0.3 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Alg6_Alg8 PF03155.10 EKG10871.1 - 8.4e-10 38.0 0.1 1.1e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.17 EKG10872.1 - 3.6e-39 132.2 0.0 9.2e-12 44.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG10872.1 - 9.3e-39 131.2 0.0 5e-10 39.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG10872.1 - 8.2e-17 60.8 0.0 0.0012 18.6 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EKG10872.1 - 1.1e-07 31.2 5.1 1.1e-07 31.2 3.6 5.0 5 0 0 5 5 5 1 Putative RRM domain RRM_3 PF08777.6 EKG10872.1 - 4.5e-05 23.2 0.0 0.019 14.7 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EKG10872.1 - 0.041 13.8 0.0 0.42 10.6 0.0 2.6 3 0 0 3 3 3 0 RNA binding domain DEAD PF00270.24 EKG10874.1 - 1.8e-30 105.6 0.0 3.5e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG10874.1 - 1.5e-17 63.1 0.4 3.7e-17 61.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG10874.1 - 0.00075 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EKG10874.1 - 0.056 12.2 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Anillin PF08174.6 EKG10875.1 - 9.9e-32 109.8 0.0 5.2e-31 107.5 0.0 2.4 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EKG10875.1 - 7.6e-09 35.7 0.0 2.8e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 PH domain DUF2599 PF10783.4 EKG10875.1 - 0.0011 19.5 0.2 0.004 17.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2599) SET PF00856.23 EKG10877.1 - 2.7e-09 37.5 4.8 1.8e-08 34.8 0.0 3.4 2 2 1 3 3 3 1 SET domain Ribosomal_L14 PF00238.14 EKG10878.1 - 3.3e-45 152.7 1.1 3.8e-45 152.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e ATP-synt_ab PF00006.20 EKG10878.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_POL_M_15KD PF02150.11 EKG10879.1 - 1.4e-09 37.4 4.9 1.4e-09 37.4 3.4 3.2 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EKG10879.1 - 0.0087 15.8 8.3 0.49 10.2 0.3 2.6 2 0 0 2 2 2 2 Double zinc ribbon FYVE PF01363.16 EKG10879.1 - 0.011 15.6 1.4 4 7.3 0.0 2.3 2 0 0 2 2 2 0 FYVE zinc finger GFA PF04828.9 EKG10879.1 - 0.023 14.6 3.8 2.4 8.1 0.5 2.8 2 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme FYDLN_acid PF09538.5 EKG10879.1 - 0.18 12.4 4.9 0.71 10.4 3.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.17 EKG10879.1 - 1.2 8.9 9.6 0.72 9.6 0.2 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.1 EKG10879.1 - 4.2 7.1 16.0 4.3 7.0 0.2 3.7 3 1 1 4 4 4 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.6 EKG10879.1 - 4.9 6.8 7.9 0.35 10.5 0.7 2.3 2 1 0 2 2 2 0 Putative transposase DNA-binding domain IBR PF01485.16 EKG10879.1 - 9.6 6.1 11.2 8.6 6.3 1.2 2.4 1 1 1 2 2 2 0 IBR domain Rotamase PF00639.16 EKG10881.1 - 9.9e-25 87.1 0.3 3e-24 85.5 0.0 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EKG10881.1 - 9.1e-19 67.8 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EKG10881.1 - 5.2e-09 35.7 2.1 5.6e-09 35.6 0.5 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EKG10881.1 - 2.4e-06 28.2 0.0 4.6e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain OEP PF02321.13 EKG10881.1 - 0.062 12.8 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DUF605 PF04652.11 EKG10882.1 - 3.5 6.9 14.0 4.3 6.6 9.7 1.1 1 0 0 1 1 1 0 Vta1 like UCH PF00443.24 EKG10883.1 - 8.8e-48 162.7 0.0 2.1e-47 161.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EKG10883.1 - 6e-28 97.3 0.3 1.1e-27 96.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EKG10883.1 - 6.2e-27 94.8 0.1 4.2e-26 92.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase WBP-1 PF11669.3 EKG10885.1 - 0.14 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 SE PF08491.5 EKG10886.1 - 7.2e-102 339.9 0.0 9e-102 339.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EKG10886.1 - 6.1e-13 48.3 0.2 2.2e-08 33.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EKG10886.1 - 1.3e-10 40.8 0.5 5e-10 38.9 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EKG10886.1 - 1.9e-06 27.2 1.7 3.1e-06 26.5 1.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EKG10886.1 - 1.9e-06 26.9 0.1 0.00021 20.2 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EKG10886.1 - 2.8e-06 26.4 2.0 4.8e-05 22.3 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EKG10886.1 - 1.5e-05 24.9 0.5 3.9e-05 23.5 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG10886.1 - 2.5e-05 24.2 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EKG10886.1 - 3.2e-05 22.7 1.0 0.0011 17.7 0.2 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EKG10886.1 - 0.0011 18.1 0.1 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EKG10886.1 - 0.0033 15.9 0.6 0.0053 15.2 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 EKG10886.1 - 0.0052 16.4 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EKG10886.1 - 0.0064 15.4 0.6 0.22 10.4 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EKG10886.1 - 0.011 15.4 0.1 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EKG10886.1 - 0.024 14.0 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EKG10886.1 - 0.038 13.8 0.2 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 EKG10886.1 - 0.078 13.3 0.9 0.12 12.7 0.2 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG10886.1 - 0.082 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SRP72 PF08492.7 EKG10888.1 - 2.4e-14 53.4 9.6 2.4e-14 53.4 6.6 2.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EKG10888.1 - 0.00028 20.9 12.2 0.075 13.1 2.8 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EKG10888.1 - 0.0018 18.5 32.0 0.19 12.0 1.8 7.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG10888.1 - 0.026 15.2 5.4 0.026 15.2 3.7 6.8 5 2 3 8 8 8 0 Tetratricopeptide repeat TilS PF09179.6 EKG10888.1 - 0.07 13.1 2.1 3.8 7.6 0.0 3.6 2 1 0 2 2 2 0 TilS substrate binding domain TPR_1 PF00515.23 EKG10888.1 - 0.071 12.7 2.2 15 5.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKG10888.1 - 0.13 12.2 19.2 2.6 8.1 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 EKG10888.1 - 0.19 11.8 11.0 3.8 7.6 0.9 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG10888.1 - 0.29 11.8 36.0 6.1 7.7 0.7 8.7 7 3 2 9 9 9 0 Tetratricopeptide repeat FXR1P_C PF12235.3 EKG10888.1 - 0.45 10.6 6.5 0.99 9.4 0.1 3.3 3 0 0 3 3 3 0 Fragile X-related 1 protein C terminal TPR_17 PF13431.1 EKG10888.1 - 8.6 6.8 7.2 11 6.5 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIE_alpha PF02002.12 EKG10889.1 - 5.9e-09 35.3 0.2 1.2e-08 34.4 0.2 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit PhnA_Zn_Ribbon PF08274.7 EKG10889.1 - 0.046 13.5 0.1 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon TLP-20 PF06088.6 EKG10889.1 - 0.28 10.8 3.8 0.25 11.0 1.3 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Hex_IIIa PF02455.11 EKG10889.1 - 0.54 8.8 2.5 0.98 8.0 1.7 1.4 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) zf-FPG_IleRS PF06827.9 EKG10889.1 - 1.3 8.7 3.6 3.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF4611 PF15387.1 EKG10889.1 - 1.3 9.1 9.2 0.85 9.8 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PseudoU_synth_1 PF01416.15 EKG10890.1 - 1.2e-20 73.9 0.0 6.5e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Velvet PF11754.3 EKG10891.1 - 2.7e-64 216.5 0.0 4.9e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Velvet factor Dicty_REP PF05086.7 EKG10891.1 - 0.57 7.8 1.5 0.76 7.4 1.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EKG10891.1 - 0.98 9.1 7.1 2.2 8.0 4.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) CTP_synth_N PF06418.9 EKG10892.1 - 3.5e-75 252.6 0.5 5.4e-75 252.0 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EKG10892.1 - 1.2e-55 187.9 0.0 2e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EKG10892.1 - 4.1e-06 26.3 0.0 1.2e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 NUDIX PF00293.23 EKG10893.1 - 4.1e-17 62.0 0.0 6.8e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Aldo_ket_red PF00248.16 EKG10894.1 - 4.3e-54 183.2 0.0 5.3e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pmp3 PF01679.12 EKG10895.1 - 4e-10 39.2 7.4 5.5e-10 38.7 5.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1656 PF07869.7 EKG10895.1 - 0.17 11.6 2.4 0.28 10.9 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) NapE PF06796.6 EKG10895.1 - 2.3 7.5 5.6 0.52 9.6 1.0 1.9 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE MFS_1 PF07690.11 EKG10897.1 - 1.8e-32 112.4 30.4 2.4e-28 98.8 15.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG10897.1 - 1.1e-06 27.2 1.9 1.1e-06 27.2 1.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2428 PF10350.4 EKG10898.1 - 1.2e-70 237.5 0.0 2.3e-70 236.5 0.0 1.5 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT_EZ PF13513.1 EKG10898.1 - 2.7e-05 24.5 10.2 0.0034 17.8 0.6 5.2 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 EKG10898.1 - 0.00021 21.1 16.8 0.049 13.7 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EKG10898.1 - 0.00026 21.2 9.5 0.48 10.7 0.1 5.5 6 0 0 6 6 6 2 HEAT repeats DUF1546 PF07571.8 EKG10898.1 - 0.068 13.2 0.3 3.8 7.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) Tim17 PF02466.14 EKG10899.1 - 3e-29 101.6 2.3 3.9e-29 101.3 1.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 EKG10899.1 - 0.17 11.2 1.5 0.23 10.7 1.0 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT LRR_4 PF12799.2 EKG10900.1 - 9.5e-42 140.0 30.8 5.7e-10 38.5 2.6 7.1 4 2 3 8 8 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG10900.1 - 1.2e-19 69.7 32.6 1.8e-08 33.9 4.8 5.4 1 1 7 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EKG10900.1 - 4.5e-16 56.4 25.8 0.7 10.1 0.1 11.9 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_7 PF13504.1 EKG10900.1 - 1.5e-11 42.4 15.5 3.1 8.4 0.1 10.8 10 1 1 11 11 11 2 Leucine rich repeat LRR_6 PF13516.1 EKG10900.1 - 2.2e-11 42.5 21.0 0.13 12.4 0.1 10.7 5 3 4 9 9 9 3 Leucine Rich repeat LRR_9 PF14580.1 EKG10900.1 - 2.5e-08 33.6 12.7 0.00015 21.3 1.1 4.1 1 1 4 5 5 5 4 Leucine-rich repeat NIF PF03031.13 EKG10901.1 - 1.2e-50 171.2 0.1 1.6e-50 170.8 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ILVD_EDD PF00920.16 EKG10902.1 - 2e-209 696.3 0.2 2.3e-209 696.1 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 EKG10902.1 - 0.05 13.5 0.0 1 9.3 0.0 2.5 3 0 0 3 3 3 0 5'-nucleotidase, C-terminal domain Zip PF02535.17 EKG10903.1 - 1e-32 113.4 11.4 6e-24 84.6 3.1 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter MFS_1 PF07690.11 EKG10903.1 - 0.0017 17.1 6.4 0.0017 17.1 4.4 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF4094 PF13334.1 EKG10903.1 - 0.055 13.8 0.3 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Kinesin PF00225.18 EKG10904.1 - 1.2e-104 349.6 0.2 1.2e-104 349.6 0.1 1.8 2 0 0 2 2 2 1 Kinesin motor domain Apolipoprotein PF01442.13 EKG10904.1 - 0.12 11.8 47.8 22 4.4 28.4 3.2 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 EKG10904.1 - 0.3 10.2 18.9 0.0086 15.2 3.9 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein AAA_22 PF13401.1 EKG10904.1 - 0.35 11.0 0.0 0.35 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain WEMBL PF05701.6 EKG10904.1 - 0.35 9.2 58.9 1.4 7.2 40.9 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 EKG10904.1 - 0.38 8.0 49.5 0.64 7.2 34.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Acyltransferase PF01553.16 EKG10905.1 - 0.0019 17.6 0.0 0.016 14.6 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase DUF1349 PF07081.6 EKG10907.1 - 3.9e-23 81.7 0.1 1.5e-12 47.2 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1349) Carb_bind PF10645.4 EKG10909.1 - 4.1e-15 55.3 8.6 5.6e-15 54.8 6.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding DUF3530 PF12048.3 EKG10909.1 - 0.0068 15.4 1.5 0.007 15.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) BMF PF15185.1 EKG10909.1 - 0.044 13.0 1.0 0.063 12.5 0.7 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF1180 PF06679.7 EKG10909.1 - 6.8 6.5 6.0 0.42 10.5 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Abhydrolase_1 PF00561.15 EKG10911.1 - 3.9e-21 75.6 0.0 1.6e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG10911.1 - 2.7e-11 43.8 0.6 3.8e-10 40.0 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EKG10911.1 - 0.0003 20.2 0.0 0.00054 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EKG10911.1 - 0.027 14.2 0.1 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pro-kuma_activ PF09286.6 EKG10912.1 - 0.017 15.1 0.0 0.022 14.8 0.0 1.3 1 1 0 1 1 1 0 Pro-kumamolisin, activation domain DUF4265 PF14085.1 EKG10912.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) DHFR_1 PF00186.14 EKG10913.1 - 3.2e-25 88.5 0.0 1.3e-17 63.8 0.0 2.9 2 1 0 2 2 2 2 Dihydrofolate reductase RibD_C PF01872.12 EKG10913.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 1 0 1 1 1 0 RibD C-terminal domain Med22 PF06179.7 EKG10914.1 - 4e-15 55.7 2.0 5.1e-15 55.4 1.4 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex eIF-5_eIF-2B PF01873.12 EKG10915.1 - 1.9e-40 137.3 0.1 3.1e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EKG10915.1 - 1.4e-25 88.9 0.8 3.5e-25 87.7 0.5 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 EKG10915.1 - 0.23 11.4 0.9 0.58 10.1 0.6 1.7 1 0 0 1 1 1 0 Zinc ribbon domain DUF3632 PF12311.3 EKG10917.1 - 3.4e-08 33.4 0.1 4.6e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) NUDIX PF00293.23 EKG10919.1 - 3.6e-05 23.4 0.1 8.5e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain HAD PF12710.2 EKG10920.1 - 2.8e-17 63.5 0.1 7.3e-17 62.1 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EKG10920.1 - 8.7e-16 57.6 0.0 1.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EKG10920.1 - 5.4e-13 48.7 0.0 1.4e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EKG10920.1 - 7.8e-12 46.0 5.7 1.2e-10 42.1 4.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG10920.1 - 0.0054 16.3 0.5 0.019 14.5 0.2 1.9 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EKG10920.1 - 0.065 13.4 0.2 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MRP-L46 PF11788.3 EKG10921.1 - 7.5e-34 116.7 0.2 1.5e-33 115.7 0.2 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Homeobox PF00046.24 EKG10922.1 - 3.3e-08 33.0 0.0 1e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EKG10922.1 - 0.00066 18.6 0.0 0.0021 17.0 0.0 1.8 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 EKG10922.1 - 0.0014 18.3 0.0 0.0071 16.0 0.0 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EKG10923.1 - 6.5e-07 28.8 1.8 1.3e-06 27.9 0.5 2.1 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EKG10923.1 - 0.00014 21.4 0.3 0.00047 19.8 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.21 EKG10923.1 - 0.00039 20.6 10.6 0.17 12.2 0.3 3.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG10923.1 - 0.00085 19.4 14.9 0.047 14.0 0.9 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG10923.1 - 0.0078 16.3 0.8 0.0078 16.3 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Homez PF11569.3 EKG10923.1 - 0.086 11.9 0.3 0.22 10.6 0.2 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-met PF12874.2 EKG10923.1 - 0.66 10.2 4.1 8.6 6.7 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zip PF02535.17 EKG10924.1 - 4.2e-39 134.4 18.1 2.3e-28 99.1 8.4 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter Acetyltransf_10 PF13673.1 EKG10925.1 - 0.075 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG10925.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain E1_dh PF00676.15 EKG10926.1 - 2.7e-117 390.8 0.0 3.2e-117 390.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EKG10926.1 - 0.0004 19.4 0.0 0.00062 18.7 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Beta_elim_lyase PF01212.16 EKG10926.1 - 0.095 11.8 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Beta-eliminating lyase P22_AR_C PF10548.4 EKG10926.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 P22AR C-terminal domain HK PF02110.10 EKG10928.1 - 2.9e-60 203.4 0.7 3.3e-60 203.2 0.5 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.12 EKG10928.1 - 1.6e-05 24.3 1.0 2.4e-05 23.7 0.7 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EKG10928.1 - 3.2e-05 23.2 1.3 7.8e-05 21.9 0.9 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HTH_22 PF13309.1 EKG10928.1 - 0.065 13.0 0.0 3.9 7.3 0.0 2.3 2 0 0 2 2 2 0 HTH domain TMP-TENI PF02581.12 EKG10929.1 - 1.3e-27 96.1 0.0 1.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Tmemb_170 PF10190.4 EKG10931.1 - 0.00077 19.4 6.9 0.00097 19.1 4.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Wzz PF02706.10 EKG10931.1 - 0.17 11.6 1.2 0.3 10.8 0.8 1.4 1 0 0 1 1 1 0 Chain length determinant protein DUF3671 PF12420.3 EKG10931.1 - 0.68 9.9 2.1 0.71 9.8 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function Peptidase_M14 PF00246.19 EKG10934.1 - 1e-69 235.3 0.0 1.3e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 EKG10934.1 - 0.1 11.4 0.0 0.42 9.4 0.0 1.8 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Sec7 PF01369.15 EKG10935.1 - 2.5e-39 134.9 0.0 4e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EKG10935.1 - 1.3e-09 38.2 0.0 2.7e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EKG10935.1 - 2.4e-07 30.9 0.0 5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Fzo_mitofusin PF04799.8 EKG10935.1 - 0.12 11.7 0.1 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 fzo-like conserved region Mito_carr PF00153.22 EKG10936.1 - 2.6e-13 49.4 0.0 3.3e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Cofilin_ADF PF00241.15 EKG10937.1 - 7.5e-20 71.1 0.0 2e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF3538 PF12057.3 EKG10937.1 - 0.00049 19.7 0.0 0.0013 18.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3538) adh_short_C2 PF13561.1 EKG10938.1 - 3e-22 79.5 0.0 3.5e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG10938.1 - 2.1e-18 66.7 0.0 2.1e-18 66.7 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG10938.1 - 2.2e-06 27.4 0.0 8.6e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 KR domain zf-TFIIB PF13453.1 EKG10938.1 - 0.097 11.8 0.1 0.77 8.9 0.0 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger FAD_binding_1 PF00667.15 EKG10940.1 - 6e-19 68.3 0.0 8.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EKG10940.1 - 1.3e-13 51.5 0.0 2.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.17 EKG10941.1 - 3e-28 97.2 0.1 1.4e-14 53.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG10941.1 - 1.9e-23 82.1 0.0 2.2e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG10941.1 - 9e-09 35.0 0.0 0.00035 20.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EKG10941.1 - 0.57 8.6 2.5 0.79 8.1 1.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PNRC PF15365.1 EKG10942.1 - 0.046 13.7 0.4 0.046 13.7 0.3 2.5 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Vps5 PF09325.5 EKG10943.1 - 3.9e-17 62.2 2.8 7.3e-17 61.4 2.0 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EKG10943.1 - 3.3e-09 36.5 0.0 7e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EKG10943.1 - 0.012 14.8 1.9 0.024 13.8 1.3 1.4 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein TPR_1 PF00515.23 EKG10943.1 - 0.068 12.8 0.2 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKG10943.1 - 0.089 12.4 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 TPR repeat PAT1 PF09770.4 EKG10943.1 - 4.5 5.3 24.2 7.6 4.6 16.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_1 PF00561.15 EKG10944.1 - 8e-44 149.8 0.0 7.2e-43 146.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG10944.1 - 2.2e-13 50.6 1.2 2.4e-12 47.2 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG10944.1 - 0.00028 20.6 0.1 0.0067 16.1 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EKG10944.1 - 0.0027 16.3 0.0 0.0036 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_4 PF08386.5 EKG10944.1 - 0.057 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein SMK-1 PF04802.10 EKG10945.1 - 4.7e-79 264.4 6.2 9.8e-79 263.3 4.3 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF914 PF06027.7 EKG10947.1 - 6.3e-107 357.2 18.8 7.7e-107 357.0 13.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EKG10947.1 - 0.00078 19.1 24.5 0.051 13.2 5.3 2.9 2 1 1 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 EKG10947.1 - 0.059 13.4 33.6 0.049 13.6 9.5 2.4 2 0 0 2 2 2 0 EamA-like transporter family HCV_env PF01539.12 EKG10947.1 - 0.071 12.5 0.8 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 CAP59_mtransfer PF11735.3 EKG10949.1 - 1.3e-73 247.1 0.0 1.8e-73 246.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 p450 PF00067.17 EKG10950.1 - 2.5e-51 174.6 0.0 3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4389 PF14333.1 EKG10954.1 - 0.12 12.1 0.0 0.12 12.1 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4389) EamA PF00892.15 EKG10954.1 - 3 7.9 9.0 0.63 10.0 0.2 2.9 3 0 0 3 3 3 0 EamA-like transporter family DUF4118 PF13493.1 EKG10954.1 - 3.7 7.7 7.3 2.2 8.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) Tannase PF07519.6 EKG10955.1 - 1.2e-107 360.5 0.1 1.6e-107 360.1 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EKG10955.1 - 5.8e-07 29.3 0.0 0.0032 17.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG10955.1 - 9.2e-06 25.3 0.0 1.3e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG10955.1 - 9.3e-06 25.0 0.3 0.0023 17.2 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EKG10955.1 - 9.1e-05 22.4 0.0 0.0002 21.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1772 PF08592.6 EKG10957.1 - 0.032 13.9 1.9 0.094 12.4 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF3815 PF12821.2 EKG10957.1 - 0.21 11.5 1.9 1.6 8.6 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3815) adh_short PF00106.20 EKG10958.1 - 1.2e-18 67.6 2.8 2.1e-18 66.7 1.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG10958.1 - 1.3e-18 67.6 0.1 2.1e-18 66.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG10958.1 - 8.4e-07 28.8 2.2 5.9e-06 26.0 1.5 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EKG10958.1 - 0.082 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EKG10958.1 - 0.1 12.0 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ThiF PF00899.16 EKG10959.1 - 1.6e-34 118.6 0.0 3e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family WSC PF01822.14 EKG10959.1 - 7.1e-09 35.4 14.4 7.1e-09 35.4 10.0 2.2 2 0 0 2 2 2 1 WSC domain Saccharop_dh PF03435.13 EKG10959.1 - 0.0012 17.8 0.1 0.0025 16.8 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase Glyco_hydro_17 PF00332.13 EKG10959.1 - 0.0056 15.7 0.8 0.0091 15.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 TrkA_N PF02254.13 EKG10959.1 - 0.0066 16.4 0.2 0.11 12.4 0.0 2.8 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_7 PF13241.1 EKG10959.1 - 0.026 14.7 0.0 0.1 12.8 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding DNA_pol_B_thumb PF14791.1 EKG10960.1 - 9.9e-22 76.4 0.0 2e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EKG10960.1 - 4.9e-19 67.6 0.5 9.3e-19 66.7 0.4 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EKG10960.1 - 8.1e-16 58.0 0.0 1.6e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EKG10960.1 - 8.3e-10 38.7 0.0 2.1e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EKG10960.1 - 0.029 14.5 0.0 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EKG10960.1 - 0.034 14.4 0.1 0.087 13.1 0.1 1.8 1 1 0 1 1 1 0 Nucleotidyltransferase domain Pyr_redox_3 PF13738.1 EKG10961.1 - 6.3e-29 101.4 0.0 1.4e-28 100.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG10961.1 - 1.7e-23 82.6 0.1 7.6e-21 73.8 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EKG10961.1 - 1.4e-12 47.2 0.3 8.2e-09 34.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EKG10961.1 - 8.7e-12 45.3 0.0 3.6e-10 40.0 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG10961.1 - 5.7e-08 32.6 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG10961.1 - 1.6e-06 27.2 0.0 2.6e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG10961.1 - 8.3e-05 22.9 0.2 0.66 10.4 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG10961.1 - 0.0015 18.3 0.0 0.056 13.2 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 EKG10961.1 - 0.0024 17.0 0.3 0.0088 15.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EKG10961.1 - 0.0089 14.9 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EKG10961.1 - 0.032 14.3 0.3 7.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EKG10961.1 - 0.045 12.6 0.0 0.096 11.5 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EKG10961.1 - 3.1 6.1 4.3 0.59 8.5 0.4 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF3445 PF11927.3 EKG10962.1 - 3.5e-70 236.2 0.0 4.9e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ADH_N PF08240.7 EKG10963.1 - 2.5e-11 43.2 0.0 4.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG10963.1 - 3.6e-10 39.4 0.1 5.9e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CD34_antigen PF06365.7 EKG10967.1 - 0.093 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Dockerin_1 PF00404.13 EKG10967.1 - 0.24 11.1 1.5 0.43 10.3 1.0 1.4 1 0 0 1 1 1 0 Dockerin type I repeat JAB PF01398.16 EKG10968.1 - 4e-09 36.2 0.0 9.2e-09 35.0 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EKG10968.1 - 0.0033 17.4 0.0 0.012 15.7 0.0 1.9 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function ADH_zinc_N PF00107.21 EKG10969.1 - 2.3e-16 59.5 0.7 3.6e-16 58.8 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EKG10969.1 - 0.036 13.4 0.1 0.068 12.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EKG10969.1 - 0.099 12.4 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 ThiF family Abhydrolase_6 PF12697.2 EKG10970.1 - 2.1e-32 112.8 0.0 3.2e-32 112.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG10970.1 - 2.9e-20 72.8 0.0 2.3e-19 69.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG10970.1 - 5.7e-12 45.6 0.0 1.7e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG10970.1 - 0.00099 18.9 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EKG10970.1 - 0.12 11.7 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pinin_SDK_memA PF04696.8 EKG10971.1 - 6e-27 93.8 14.3 6e-27 93.8 9.9 2.4 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region DUF2713 PF10897.3 EKG10971.1 - 0.0088 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2713) CENP-T PF15511.1 EKG10971.1 - 0.91 8.7 36.7 1.3 8.1 25.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PHF5 PF03660.9 EKG10972.1 - 4.6e-52 174.6 9.3 5.1e-52 174.4 6.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EKG10972.1 - 0.88 9.4 15.5 0.22 11.3 5.5 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EKG10972.1 - 1.4 8.7 15.7 2.9 7.6 0.5 3.0 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EKG10972.1 - 7.7 6.3 15.6 0.2 11.4 4.4 2.5 1 1 1 2 2 2 0 PHD-finger PolC_DP2 PF03833.8 EKG10972.1 - 9.8 3.6 6.8 10 3.6 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ribonuc_red_lgC PF02867.10 EKG10973.1 - 4.4e-218 725.2 0.0 7.3e-218 724.4 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EKG10973.1 - 5.3e-25 87.0 0.0 1.3e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EKG10973.1 - 1.8e-16 60.3 0.1 7.1e-16 58.4 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EKG10973.1 - 0.043 11.9 0.0 0.065 11.3 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase DAO PF01266.19 EKG10975.1 - 1.4e-13 50.4 0.2 1.8e-13 50.1 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase PDT PF00800.13 EKG10976.1 - 0.022 14.2 0.9 0.022 14.2 0.6 2.0 1 1 1 2 2 2 0 Prephenate dehydratase Macoilin PF09726.4 EKG10976.1 - 5.1 5.2 8.1 5.4 5.1 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Rgp1 PF08737.5 EKG10977.1 - 1.2e-119 400.1 0.0 3.3e-119 398.6 0.0 1.7 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EKG10977.1 - 0.00015 21.5 0.1 0.00087 19.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Neugrin PF06413.6 EKG10978.1 - 3.8e-12 46.5 2.0 3.8e-12 46.5 1.4 1.9 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 EKG10978.1 - 2.7e-09 37.1 5.6 5.8e-09 36.1 3.9 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF2236 PF09995.4 EKG10979.1 - 2.4e-36 125.2 1.9 3.7e-36 124.6 1.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Avidin PF01382.12 EKG10979.1 - 0.0088 16.3 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Avidin family PTR2 PF00854.16 EKG10980.1 - 5.5e-40 137.2 9.3 5.5e-40 137.2 6.5 1.4 2 0 0 2 2 2 1 POT family CcmH PF03918.9 EKG10980.1 - 0.31 10.0 0.8 10 5.1 0.0 2.9 2 1 1 3 3 3 0 Cytochrome C biogenesis protein Herpes_US9 PF06072.6 EKG10980.1 - 6.6 6.6 13.5 6 6.7 0.2 3.8 3 1 0 3 3 3 0 Alphaherpesvirus tegument protein US9 Amidohydro_5 PF13594.1 EKG10981.1 - 5.8e-13 48.4 0.0 2.1e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG10981.1 - 6.2e-09 35.9 0.0 7.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG10981.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase DUF4310 PF14187.1 EKG10981.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) HpcH_HpaI PF03328.9 EKG10982.1 - 1.5e-05 23.9 0.0 1.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SLAC1 PF03595.12 EKG10983.1 - 4.1e-72 242.6 48.7 5.1e-72 242.3 33.8 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2183 PF09949.4 EKG10984.1 - 7.4e-33 112.4 0.0 1.6e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Peptidase_M20 PF01546.23 EKG10987.1 - 1.9e-10 40.5 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EKG10987.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Telomere_Sde2 PF13019.1 EKG10988.1 - 2.5e-63 212.6 0.2 4.8e-63 211.6 0.1 1.5 1 0 0 1 1 1 1 Telomere stability and silencing S10_plectin PF03501.10 EKG10989.1 - 9.9e-41 137.5 0.3 1.2e-40 137.2 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Bac_luciferase PF00296.15 EKG10991.1 - 1.1e-60 205.3 0.1 1.7e-60 204.7 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.21 EKG10991.1 - 8.5e-08 31.8 0.1 1.7e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG10991.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SNF2_N PF00176.18 EKG10992.1 - 1.1e-33 116.3 0.0 4.6e-32 111.0 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG10992.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Pox_F17 PF04767.7 EKG10994.1 - 0.35 11.1 2.6 1.1 9.6 1.8 1.7 1 1 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein eIF3_subunit PF08597.5 EKG10994.1 - 1.9 8.0 11.1 2.5 7.5 7.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4557 PF15101.1 EKG10994.1 - 6.4 6.5 8.6 8.2 6.2 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SOBP PF15279.1 EKG10994.1 - 6.5 7.0 11.1 7.4 6.8 7.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Trypan_PARP PF05887.6 EKG10995.1 - 1.6 8.5 20.5 3.4 7.4 14.0 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 EKG10995.1 - 7.3 4.8 16.2 4.8 5.4 10.3 1.3 1 1 0 1 1 1 0 Neisseria meningitidis TspB protein DUF2470 PF10615.4 EKG10996.1 - 1.1e-21 76.8 0.1 1.6e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) GAS2 PF02187.12 EKG10997.1 - 0.00022 20.9 0.1 0.00049 19.8 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain SCF PF02404.10 EKG10997.1 - 0.03 13.5 2.8 0.053 12.7 1.9 1.3 1 0 0 1 1 1 0 Stem cell factor LSM PF01423.17 EKG10998.1 - 2.7e-13 49.2 0.3 4.2e-13 48.6 0.2 1.3 1 0 0 1 1 1 1 LSM domain Hydrophobin_2 PF06766.6 EKG10999.1 - 7.8e-18 63.9 9.4 1e-17 63.5 6.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Oxidored_q6 PF01058.17 EKG11000.1 - 3.4e-23 81.6 0.0 3.9e-23 81.5 0.0 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Fungal_trans PF04082.13 EKG11002.1 - 8.7e-13 47.7 1.0 1e-12 47.4 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG11002.1 - 9.9e-06 25.3 9.9 2e-05 24.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC_2 PF13913.1 EKG11002.1 - 0.086 12.5 4.7 0.053 13.2 1.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 EKG11002.1 - 0.11 12.9 0.5 0.11 12.9 0.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.11 EKG11003.1 - 1.1e-22 80.2 49.1 1.1e-22 80.2 34.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EKG11004.1 - 1.6e-30 106.0 0.0 3.3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 EKG11005.1 - 1.5e-67 227.1 0.0 2.2e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EKG11005.1 - 5.6e-59 199.5 0.0 9e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EKG11005.1 - 2.1e-12 47.0 0.0 3.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EKG11005.1 - 1.3e-10 41.3 0.0 3.2e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG11005.1 - 1.6e-07 32.1 0.0 6.1e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EKG11005.1 - 2.6e-06 26.3 0.0 6.6e-06 25.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG11005.1 - 6.1e-06 26.3 0.0 7.1e-05 22.8 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EKG11005.1 - 0.0037 16.1 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 EKG11005.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 EKG11005.1 - 0.21 10.7 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DUF1593 PF07632.6 EKG11011.1 - 1e-88 297.0 0.0 1.3e-88 296.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EKG11011.1 - 0.0011 17.3 0.0 0.0015 16.9 0.0 1.1 1 0 0 1 1 1 1 REJ domain Aldo_ket_red PF00248.16 EKG11012.1 - 1.3e-52 178.3 0.0 1.5e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 EKG11013.1 - 9.8e-07 28.5 10.4 1.6e-06 27.8 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHQS PF01959.11 EKG11015.1 - 0.052 12.2 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) ADH_N PF08240.7 EKG11015.1 - 0.12 12.0 0.1 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Transketolase_N PF00456.16 EKG11016.1 - 6.4e-115 383.5 0.0 8.4e-115 383.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EKG11016.1 - 4.6e-40 137.0 0.1 7.5e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EKG11016.1 - 8.1e-08 32.2 0.0 3.1e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EKG11016.1 - 2.8e-05 23.1 0.0 0.00024 20.1 0.1 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EKG11016.1 - 0.00055 19.5 0.9 0.0033 17.0 0.3 2.4 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EKG11016.1 - 0.00076 18.2 0.1 0.0013 17.4 0.1 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component PGG PF13962.1 EKG11017.1 - 0.66 9.6 6.6 14 5.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function Lipocalin_5 PF13924.1 EKG11018.1 - 1.6e-10 40.8 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Arylsulfotran_2 PF14269.1 EKG11019.1 - 3.5e-59 200.3 0.7 4.6e-59 200.0 0.5 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EKG11019.1 - 6.7e-19 67.7 0.9 2.2e-18 66.0 0.1 2.0 2 0 0 2 2 2 1 Arylsulfotransferase (ASST) RFC1 PF08519.7 EKG11020.1 - 9.3e-60 200.8 0.2 5.1e-59 198.4 0.0 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EKG11020.1 - 2.5e-13 49.9 0.0 6.8e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EKG11020.1 - 2.2e-09 37.5 1.6 2.3e-09 37.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EKG11020.1 - 2.4e-05 23.2 0.0 9.1e-05 21.3 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EKG11020.1 - 3.9e-05 24.4 1.3 0.00024 21.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKG11020.1 - 8.1e-05 22.7 0.0 0.00023 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG11020.1 - 0.00028 20.9 0.0 0.0087 16.0 0.1 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EKG11020.1 - 0.0012 18.4 0.1 0.0062 16.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EKG11020.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EKG11020.1 - 0.0056 15.7 0.1 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EKG11020.1 - 0.014 15.7 0.1 0.014 15.7 0.0 2.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EKG11020.1 - 0.017 15.0 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKG11020.1 - 0.017 15.0 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKG11020.1 - 0.086 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EKG11020.1 - 0.13 11.9 0.0 0.73 9.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain SAGA-Tad1 PF12767.2 EKG11020.1 - 0.4 10.3 0.0 0.4 10.3 0.0 5.0 5 2 1 7 7 6 0 Transcriptional regulator of RNA polII, SAGA, subunit Ribosomal_L16 PF00252.13 EKG11021.1 - 5.3e-31 107.1 0.1 8.1e-31 106.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Nfu_N PF08712.6 EKG11023.1 - 1.1e-27 95.4 0.0 2e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EKG11023.1 - 4.1e-21 74.5 0.1 7.3e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Sugar_tr PF00083.19 EKG11024.1 - 2.2e-92 310.0 32.2 2.7e-92 309.7 22.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11024.1 - 8.9e-19 67.3 30.5 8.9e-19 67.3 21.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Mob1_phocein PF03637.12 EKG11025.1 - 3.2e-71 238.5 0.1 4.3e-71 238.1 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Glyco_hydro_63 PF03200.11 EKG11026.1 - 2.9e-07 28.7 3.7 1.1e-05 23.5 0.2 3.2 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase SnoaL_2 PF12680.2 EKG11027.1 - 0.15 12.4 0.0 0.52 10.7 0.0 1.8 1 1 1 2 2 2 0 SnoaL-like domain SPO22 PF08631.5 EKG11028.1 - 7.1e-42 143.3 0.1 2.1e-41 141.8 0.1 1.8 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EKG11028.1 - 0.00017 21.4 5.1 2 8.4 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat SnoaL_2 PF12680.2 EKG11028.1 - 0.068 13.5 0.1 0.31 11.4 0.1 2.2 1 0 0 1 1 1 0 SnoaL-like domain TPR_2 PF07719.12 EKG11028.1 - 0.097 12.6 5.2 2 8.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EKG11028.1 - 0.14 12.4 0.9 23 5.6 0.1 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain C2 PF00168.25 EKG11029.1 - 3e-20 71.8 0.0 3.5e-15 55.5 0.0 2.9 2 0 0 2 2 2 2 C2 domain Amidohydro_4 PF13147.1 EKG11030.1 - 3.8e-05 23.8 7.4 0.016 15.2 5.1 3.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EKG11030.1 - 6e-05 22.7 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG11030.1 - 9.6e-05 22.1 0.1 0.33 10.5 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EKG11030.1 - 0.021 14.0 0.1 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase family RabGAP-TBC PF00566.13 EKG11031.1 - 6.3e-48 163.0 1.2 6.6e-47 159.7 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain HALZ PF02183.13 EKG11031.1 - 0.078 12.7 4.8 0.15 11.7 0.6 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper RasGAP_C PF03836.10 EKG11031.1 - 0.078 12.6 5.6 0.09 12.4 0.8 2.9 1 1 2 3 3 3 0 RasGAP C-terminus PspB PF06667.7 EKG11031.1 - 0.13 12.1 0.8 0.62 10.0 0.5 2.1 1 0 0 1 1 1 0 Phage shock protein B TPR_MLP1_2 PF07926.7 EKG11031.1 - 9.1 6.0 26.0 0.72 9.5 13.2 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Trp_syntA PF00290.15 EKG11032.1 - 3.1e-93 311.0 0.0 4.6e-93 310.4 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EKG11032.1 - 2.4e-44 151.8 0.7 4.7e-44 150.8 0.5 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF2191 PF09957.4 EKG11032.1 - 0.072 12.9 0.1 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2191) Proteasome PF00227.21 EKG11033.1 - 1.3e-56 190.9 0.0 2.5e-32 111.7 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EKG11033.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.10 EKG11033.1 - 0.011 14.2 0.5 2.9 6.2 0.0 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RINGv PF12906.2 EKG11034.1 - 4e-09 36.3 2.1 4e-09 36.3 1.5 2.2 2 0 0 2 2 2 1 RING-variant domain DUF1206 PF06724.6 EKG11034.1 - 0.00095 18.8 0.9 0.00095 18.8 0.6 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1206) zf-RING_2 PF13639.1 EKG11034.1 - 0.0041 16.9 4.2 0.01 15.6 1.0 2.1 2 0 0 2 2 2 1 Ring finger domain Tetraspannin PF00335.15 EKG11034.1 - 0.043 13.0 0.7 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Tetraspanin family DUF2752 PF10825.3 EKG11034.1 - 0.066 13.2 0.5 0.16 12.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) PHD PF00628.24 EKG11034.1 - 4.7 6.9 6.5 0.56 9.9 1.5 1.7 2 0 0 2 2 2 0 PHD-finger ATG16 PF08614.6 EKG11036.1 - 2.3e-05 24.3 7.0 9.2e-05 22.3 4.2 1.7 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.6 EKG11036.1 - 0.0065 15.9 2.6 0.0065 15.9 1.8 1.7 2 0 0 2 2 2 1 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 EKG11036.1 - 0.017 14.8 13.3 0.53 10.0 9.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ALMS_motif PF15309.1 EKG11036.1 - 0.021 14.6 5.4 0.1 12.4 1.2 2.1 2 0 0 2 2 2 0 ALMS motif DUF16 PF01519.11 EKG11036.1 - 0.027 14.6 3.4 0.027 14.6 2.3 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 CENP-F_leu_zip PF10473.4 EKG11036.1 - 0.029 14.2 10.3 0.16 11.7 2.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EKG11036.1 - 0.031 14.6 2.7 4.9 7.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 EKG11036.1 - 0.036 11.8 11.9 0.029 12.1 2.1 2.0 2 0 0 2 2 2 0 Myosin tail RNA_pol_Rpb1_1 PF04997.7 EKG11036.1 - 0.041 13.1 0.2 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Spc24 PF08286.6 EKG11036.1 - 0.052 13.2 2.4 7.8 6.2 1.5 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EKG11036.1 - 0.059 12.9 4.2 0.044 13.3 0.4 2.0 2 0 0 2 2 2 0 IncA protein DUF1199 PF06712.6 EKG11036.1 - 0.091 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Cytochrom_B562 PF07361.6 EKG11036.1 - 0.33 11.3 2.9 0.18 12.2 0.6 1.6 2 0 0 2 2 2 0 Cytochrome b562 CorA PF01544.13 EKG11036.1 - 0.35 9.8 1.6 0.5 9.3 1.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DivIC PF04977.10 EKG11036.1 - 0.41 10.1 15.3 1.8 8.1 0.7 2.6 2 1 0 2 2 2 0 Septum formation initiator AATF-Che1 PF13339.1 EKG11036.1 - 0.5 10.5 5.1 0.37 10.9 2.0 1.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Mnd1 PF03962.10 EKG11036.1 - 0.61 9.7 8.8 0.16 11.6 2.9 1.9 2 0 0 2 2 2 0 Mnd1 family DUF2458 PF10454.4 EKG11036.1 - 0.62 9.9 8.3 1.4 8.7 4.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) Seryl_tRNA_N PF02403.17 EKG11036.1 - 1.3 9.0 12.4 1.1 9.2 4.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EKG11036.1 - 2.8 6.8 9.6 1.2 8.1 3.1 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 COG2 PF06148.6 EKG11036.1 - 2.9 7.7 5.8 0.61 9.9 1.5 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF904 PF06005.7 EKG11036.1 - 4.3 7.6 9.8 14 6.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) SlyX PF04102.7 EKG11036.1 - 6.2 7.2 9.5 1.3 9.4 1.5 2.5 2 1 0 2 2 2 0 SlyX Med21 PF11221.3 EKG11036.1 - 9.1 6.2 10.4 3.9 7.4 3.2 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex HSP70 PF00012.15 EKG11037.1 - 1e-13 50.1 0.0 1.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Herpes_gE PF02480.11 EKG11038.1 - 0.1 10.8 0.7 0.11 10.7 0.5 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Ribonuclease_3 PF00636.21 EKG11039.1 - 8.6e-37 126.0 0.0 2.9e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EKG11039.1 - 1.2e-24 86.6 0.1 3.7e-11 43.0 0.0 4.0 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EKG11039.1 - 1.5e-18 66.3 0.0 2.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EKG11039.1 - 1.3e-16 60.1 0.1 3.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FAD_binding_3 PF01494.14 EKG11040.1 - 2.3e-14 53.2 0.0 2.6e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 EKG11043.1 - 2.5e-17 62.6 0.0 2.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EKG11043.1 - 0.076 12.9 0.3 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Cellulase PF00150.13 EKG11044.1 - 7e-50 169.8 5.1 8e-50 169.6 3.5 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAT1 PF09770.4 EKG11046.1 - 0.18 9.9 12.2 0.24 9.6 8.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 EKG11048.1 - 0.23 9.8 8.9 0.25 9.7 6.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp12 PF04003.7 EKG11049.1 - 6.8e-21 74.2 0.0 9.8e-21 73.7 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Bromodomain PF00439.20 EKG11050.1 - 3e-41 139.2 0.9 3.7e-20 71.6 0.1 3.1 3 0 0 3 3 3 2 Bromodomain FAM74 PF15026.1 EKG11050.1 - 1.7 8.3 6.7 5.5 6.6 0.5 2.4 2 0 0 2 2 2 0 FAM74 protein DUF1176 PF06674.6 EKG11050.1 - 1.9 7.4 12.1 0.21 10.6 2.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1176) Pro_CA PF00484.14 EKG11050.1 - 2.9 7.8 4.6 3.4 7.6 1.9 2.1 1 1 1 2 2 2 0 Carbonic anhydrase TIP49 PF06068.8 EKG11051.1 - 2.5e-182 606.0 0.0 2.9e-182 605.7 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EKG11051.1 - 2.3e-11 44.0 0.1 2.1e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKG11051.1 - 2.6e-11 43.0 0.2 2.5e-07 29.9 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKG11051.1 - 8.4e-07 29.1 0.0 7.9e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG11051.1 - 7.7e-06 26.0 0.1 0.12 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EKG11051.1 - 2.1e-05 24.1 0.2 5.6e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EKG11051.1 - 4.2e-05 23.2 0.2 0.062 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EKG11051.1 - 0.00034 20.6 0.2 0.001 19.0 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKG11051.1 - 0.00091 18.6 0.2 0.0017 17.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EKG11051.1 - 0.0012 18.3 0.2 0.7 9.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 EKG11051.1 - 0.0029 16.7 0.2 0.0062 15.6 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EKG11051.1 - 0.0061 15.9 0.2 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 EKG11051.1 - 0.0088 15.0 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EKG11051.1 - 0.012 15.0 0.3 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EKG11051.1 - 0.013 15.3 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EKG11051.1 - 0.014 14.5 0.3 0.74 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EKG11051.1 - 0.02 14.1 0.2 0.11 11.7 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EKG11051.1 - 0.026 13.6 0.4 0.088 11.9 0.0 1.8 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.10 EKG11051.1 - 0.031 13.1 0.0 0.053 12.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EKG11051.1 - 0.072 13.9 0.1 0.16 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKG11051.1 - 0.1 12.9 0.1 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EKG11051.1 - 0.18 11.5 1.1 1.9 8.1 0.0 2.7 3 0 0 3 3 3 0 NTPase DUF914 PF06027.7 EKG11052.1 - 0.079 11.7 0.1 0.079 11.7 0.1 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) HET PF06985.6 EKG11053.1 - 5.6e-29 101.0 0.0 1.3e-28 99.8 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PolC_DP2 PF03833.8 EKG11053.1 - 0.093 10.3 0.0 0.13 9.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 AA_permease_2 PF13520.1 EKG11054.1 - 4.9e-30 104.4 25.6 5.5e-30 104.2 17.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG11054.1 - 1.1e-13 50.4 22.1 1.2e-13 50.2 15.3 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 EKG11054.1 - 0.065 12.1 0.1 0.15 11.0 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M50 PepSY_TM_2 PF13703.1 EKG11054.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.6 4 1 0 4 4 4 0 PepSY-associated TM helix Colicin_V PF02674.11 EKG11054.1 - 3 7.6 22.6 1.1 9.1 5.8 3.0 1 1 1 3 3 3 0 Colicin V production protein MFS_1 PF07690.11 EKG11055.1 - 5.6e-27 94.3 34.5 9.4e-27 93.6 23.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Cation_efflux PF01545.16 EKG11056.1 - 4.1e-38 131.0 3.5 5e-38 130.7 2.4 1.1 1 0 0 1 1 1 1 Cation efflux family DUF3043 PF11241.3 EKG11056.1 - 0.088 12.3 0.1 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Glyco_hydro_88 PF07470.8 EKG11057.1 - 6.9e-12 45.0 0.1 6.8e-11 41.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 AAA_5 PF07728.9 EKG11058.1 - 5.2e-132 434.4 0.5 7.3e-22 77.5 0.0 9.5 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKG11058.1 - 5.6e-32 110.0 0.0 4.7e-11 42.4 0.0 8.4 7 1 1 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EKG11058.1 - 4e-30 104.7 0.0 1.6e-05 25.1 0.0 7.0 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG11058.1 - 9.7e-27 94.1 0.0 0.00073 20.3 0.0 8.1 7 0 0 7 7 6 5 AAA domain AAA_16 PF13191.1 EKG11058.1 - 1.7e-25 90.1 14.1 5.7e-06 26.4 0.2 8.6 7 0 0 7 7 6 4 AAA ATPase domain AAA_33 PF13671.1 EKG11058.1 - 9.7e-25 87.1 0.0 0.00027 20.8 0.0 7.5 6 1 0 6 6 6 5 AAA domain AAA_22 PF13401.1 EKG11058.1 - 1.6e-23 83.3 0.1 0.0094 16.0 0.0 7.9 7 0 0 7 7 6 6 AAA domain AAA_14 PF13173.1 EKG11058.1 - 5.2e-21 74.8 0.0 9.5e-05 22.2 0.0 8.0 8 0 0 8 8 7 2 AAA domain Sigma54_activ_2 PF14532.1 EKG11058.1 - 1.1e-20 74.0 1.2 8.8e-05 22.5 0.0 7.4 7 0 0 7 7 6 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 EKG11058.1 - 1.4e-20 73.4 0.0 0.018 14.4 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain AAA_18 PF13238.1 EKG11058.1 - 1.6e-20 73.7 0.5 0.025 14.9 0.0 7.1 6 0 0 6 6 6 4 AAA domain AAA_19 PF13245.1 EKG11058.1 - 1.9e-17 62.7 5.2 0.0092 15.7 0.1 7.1 6 0 0 6 6 6 3 Part of AAA domain T2SE PF00437.15 EKG11058.1 - 3.8e-17 62.0 0.3 0.016 14.1 0.0 6.4 6 0 0 6 6 6 5 Type II/IV secretion system protein UPF0079 PF02367.12 EKG11058.1 - 1.7e-16 59.9 4.5 0.013 15.1 0.0 6.7 7 0 0 7 7 6 4 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EKG11058.1 - 2.2e-16 59.6 0.1 0.2 10.8 0.0 8.9 9 0 0 9 9 8 3 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EKG11058.1 - 5.6e-15 54.9 0.2 0.11 11.5 0.0 7.5 7 0 0 7 7 7 3 Zeta toxin ABC_tran PF00005.22 EKG11058.1 - 5.6e-15 55.8 6.7 0.046 14.0 0.0 7.4 7 0 0 7 7 6 3 ABC transporter RNA_helicase PF00910.17 EKG11058.1 - 9.7e-15 54.6 2.1 0.11 12.6 0.0 6.8 6 0 0 6 6 6 3 RNA helicase RuvB_N PF05496.7 EKG11058.1 - 4.8e-14 51.9 0.2 0.11 11.5 0.0 6.5 6 0 0 6 6 6 2 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EKG11058.1 - 2.9e-13 49.8 8.4 0.26 10.9 0.0 6.0 6 0 0 6 6 5 4 NACHT domain DUF258 PF03193.11 EKG11058.1 - 4.2e-12 45.5 0.3 0.18 10.9 0.0 6.2 6 0 0 6 6 6 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EKG11058.1 - 9.9e-12 45.1 6.1 0.26 11.2 0.0 7.1 6 0 0 6 6 6 2 AAA domain AAA_29 PF13555.1 EKG11058.1 - 2.2e-11 43.1 0.2 1 8.9 0.0 6.3 6 0 0 6 6 6 3 P-loop containing region of AAA domain AAA_25 PF13481.1 EKG11058.1 - 5.9e-11 42.1 0.5 0.63 9.4 0.0 5.7 5 0 0 5 5 5 4 AAA domain MobB PF03205.9 EKG11058.1 - 6e-11 42.2 3.3 0.91 9.2 0.0 6.4 6 0 0 6 6 6 3 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EKG11058.1 - 6e-11 42.8 2.0 0.28 11.6 0.0 6.4 6 0 0 6 6 5 2 Miro-like protein Arch_ATPase PF01637.13 EKG11058.1 - 4.5e-10 39.6 0.0 0.32 10.6 0.0 6.3 6 0 0 6 6 6 1 Archaeal ATPase PduV-EutP PF10662.4 EKG11058.1 - 7.4e-10 38.4 2.3 0.036 13.5 0.0 5.7 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EKG11058.1 - 1.1e-09 38.3 0.4 0.064 13.0 0.0 6.0 6 0 0 6 6 6 2 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EKG11058.1 - 2.3e-09 36.9 0.1 1 8.7 0.0 6.1 6 0 0 6 6 6 1 IstB-like ATP binding protein Rad17 PF03215.10 EKG11058.1 - 8.1e-09 34.6 0.0 0.55 8.8 0.0 5.4 5 0 0 5 5 5 2 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 EKG11058.1 - 1.5e-08 34.3 8.6 0.67 9.3 0.0 6.3 7 0 0 7 7 6 2 SRP54-type protein, GTPase domain AAA_24 PF13479.1 EKG11058.1 - 1.2e-06 28.2 0.7 0.37 10.3 0.0 5.5 5 0 0 5 5 5 1 AAA domain SRPRB PF09439.5 EKG11058.1 - 1.5e-06 27.6 0.5 0.33 10.1 0.0 5.8 5 0 0 5 5 5 1 Signal recognition particle receptor beta subunit cobW PF02492.14 EKG11058.1 - 2.6e-06 27.0 8.8 2.7 7.4 0.0 6.9 7 0 0 7 7 7 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EKG11058.1 - 4.2e-06 26.5 6.5 0.58 9.8 0.1 5.6 5 0 0 5 5 5 1 NTPase Viral_helicase1 PF01443.13 EKG11058.1 - 8e-06 25.5 0.1 22 4.4 0.0 5.9 6 0 0 6 6 6 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EKG11058.1 - 1.7e-05 23.7 1.1 0.16 10.6 0.0 5.2 6 0 0 6 6 6 1 TIP49 C-terminus MMR_HSR1 PF01926.18 EKG11058.1 - 4.4e-05 23.4 0.7 31 4.5 0.0 5.9 6 0 0 6 6 5 0 50S ribosome-binding GTPase PhoH PF02562.11 EKG11058.1 - 4.6e-05 22.7 0.2 9.3 5.4 0.0 5.1 5 0 0 5 5 5 0 PhoH-like protein AAA_23 PF13476.1 EKG11058.1 - 5.2e-05 23.6 17.6 1.1 9.5 0.0 7.7 7 0 0 7 7 6 1 AAA domain PRK PF00485.13 EKG11058.1 - 0.00025 20.6 0.1 0.36 10.3 0.0 3.4 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 EKG11058.1 - 0.00055 19.4 1.6 1.1 8.6 0.0 5.1 6 0 0 6 6 4 1 FtsK/SpoIIIE family AAA_6 PF12774.2 EKG11058.1 - 0.0011 18.6 0.0 24 4.3 0.0 5.4 6 0 0 6 6 5 0 Hydrolytic ATP binding site of dynein motor region D1 KaiC PF06745.8 EKG11058.1 - 0.0012 18.0 0.2 5.8 5.9 0.0 4.9 5 0 0 5 5 5 0 KaiC Bac_DnaA PF00308.13 EKG11058.1 - 0.0013 18.4 0.1 16 5.0 0.0 4.6 5 0 0 5 5 4 0 Bacterial dnaA protein ATP_bind_1 PF03029.12 EKG11058.1 - 0.0015 18.1 5.3 7.9 5.9 0.0 5.7 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 EKG11058.1 - 0.0022 16.8 1.1 11 4.7 0.0 4.8 5 0 0 5 5 5 0 NB-ARC domain AAA_7 PF12775.2 EKG11058.1 - 0.0028 16.7 2.3 20 4.1 0.0 4.8 5 0 0 5 5 5 0 P-loop containing dynein motor region D3 AAA_11 PF13086.1 EKG11058.1 - 0.0031 17.1 6.7 2.9 7.4 0.0 5.9 8 0 0 8 8 5 0 AAA domain Thymidylate_kin PF02223.12 EKG11058.1 - 0.022 14.1 4.7 7.3 5.9 0.0 5.8 7 0 0 7 7 6 0 Thymidylate kinase Guanylate_kin PF00625.16 EKG11058.1 - 0.024 14.0 0.2 4 6.8 0.0 3.9 4 0 0 4 4 4 0 Guanylate kinase Septin PF00735.13 EKG11058.1 - 0.041 12.8 1.1 31 3.4 0.0 4.4 5 0 0 5 5 5 0 Septin AAA_21 PF13304.1 EKG11058.1 - 0.054 13.4 0.0 14 5.5 0.0 3.5 4 0 0 4 4 2 0 AAA domain ATP-synt_ab PF00006.20 EKG11058.1 - 0.092 12.2 0.1 10 5.5 0.0 4.0 6 0 0 6 6 4 0 ATP synthase alpha/beta family, nucleotide-binding domain tRNA_lig_kinase PF08303.6 EKG11058.1 - 0.1 12.4 0.2 0.85 9.4 0.1 2.6 2 0 0 2 2 2 0 tRNA ligase kinase domain Pox_A32 PF04665.7 EKG11058.1 - 0.13 11.4 0.3 34 3.6 0.0 3.6 4 0 0 4 4 4 0 Poxvirus A32 protein Dynamin_N PF00350.18 EKG11058.1 - 0.75 9.6 3.4 12 5.6 0.0 4.0 4 0 0 4 4 2 0 Dynamin family SKI PF01202.17 EKG11058.1 - 0.9 9.3 6.9 13 5.5 0.0 5.1 6 0 0 6 6 4 0 Shikimate kinase AAA_15 PF13175.1 EKG11058.1 - 1 8.3 0.0 63 2.4 0.0 3.5 5 0 0 5 5 4 0 AAA ATPase domain FeoB_N PF02421.13 EKG11058.1 - 2.4 7.4 3.4 18 4.6 0.1 3.7 4 0 0 4 4 3 0 Ferrous iron transport protein B APS_kinase PF01583.15 EKG11058.1 - 2.9 7.5 5.9 12 5.5 0.0 4.4 6 0 0 6 6 3 0 Adenylylsulphate kinase DUF87 PF01935.12 EKG11058.1 - 3.6 7.3 5.1 36 4.0 0.0 5.1 5 1 0 5 5 4 0 Domain of unknown function DUF87 Ribosomal_L12 PF00542.14 EKG11059.1 - 6.8e-17 61.2 3.0 1e-16 60.6 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Dermcidin PF15291.1 EKG11059.1 - 0.14 12.3 0.8 0.19 11.9 0.6 1.3 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide DUF4349 PF14257.1 EKG11059.1 - 0.58 9.3 3.9 3 7.0 2.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) CTK3 PF12243.3 EKG11060.1 - 7.3e-58 194.1 1.6 1.1e-57 193.5 1.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EKG11060.1 - 3.2e-20 71.9 9.5 9.7e-20 70.3 6.6 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 EKG11060.1 - 0.0056 16.4 0.2 0.035 13.8 0.2 2.1 1 1 1 2 2 2 1 Mitochondrial glycoprotein Fib_alpha PF08702.5 EKG11060.1 - 3.1 7.9 5.1 1.3 9.0 0.7 2.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Astro_capsid PF03115.9 EKG11061.1 - 0.027 12.7 1.3 0.032 12.5 0.9 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor P5CR_dimer PF14748.1 EKG11062.1 - 1.2e-31 108.8 0.5 2.1e-31 108.0 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EKG11062.1 - 1.9e-06 28.2 0.1 6.5e-06 26.4 0.0 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent PI3_PI4_kinase PF00454.22 EKG11063.1 - 5.3e-33 114.4 0.0 8.3e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Isochorismatase PF00857.15 EKG11063.1 - 9e-25 87.5 0.0 1.7e-16 60.6 0.0 2.4 2 0 0 2 2 2 2 Isochorismatase family Pik1 PF11522.3 EKG11063.1 - 3.5e-17 61.8 0.3 6.7e-17 60.9 0.2 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.1 EKG11063.1 - 0.022 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) PI3Ka PF00613.15 EKG11063.1 - 0.18 10.9 0.3 0.41 9.8 0.2 1.5 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cytochrom_B558a PF05038.8 EKG11064.1 - 0.09 12.3 1.5 0.12 11.9 0.0 1.8 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF605 PF04652.11 EKG11064.1 - 4.6 6.5 8.2 7.2 5.8 5.7 1.3 1 0 0 1 1 1 0 Vta1 like DUF1762 PF08574.5 EKG11065.1 - 1.9e-05 24.9 0.5 4.4e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) Nucleoside_tran PF01733.13 EKG11066.1 - 5.4e-46 157.1 17.7 1.7e-44 152.2 8.3 3.0 1 1 1 2 2 2 1 Nucleoside transporter DUF4064 PF13273.1 EKG11066.1 - 1.3 9.1 7.4 0.68 10.0 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Glyco_hydro_47 PF01532.15 EKG11067.1 - 1.6e-177 590.7 0.4 1.8e-177 590.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Med20 PF08612.6 EKG11068.1 - 6e-19 68.0 0.0 7e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Lipase_GDSL_2 PF13472.1 EKG11069.1 - 3.8e-15 56.4 6.9 6.4e-15 55.7 4.8 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EKG11069.1 - 9.7e-10 38.6 5.7 1.5e-09 38.0 4.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PSDC PF12588.3 EKG11070.1 - 1.3e-54 183.6 0.0 1.9e-54 183.1 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EKG11070.1 - 3.3e-35 121.2 0.0 5.8e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EKG11070.1 - 3.9e-06 26.4 0.4 0.083 12.5 0.1 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EKG11070.1 - 0.08 12.5 0.1 0.84 9.3 0.0 2.2 2 0 0 2 2 2 0 Biotin-requiring enzyme p450 PF00067.17 EKG11071.1 - 1.4e-40 139.1 0.0 7.2e-32 110.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 adh_short PF00106.20 EKG11072.1 - 9.2e-16 58.2 0.1 1.7e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG11072.1 - 4.5e-05 23.2 0.1 7.8e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG11072.1 - 0.002 17.9 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SBP_bac_7 PF03480.8 EKG11072.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Ras PF00071.17 EKG11073.1 - 1e-21 77.0 0.0 1.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG11073.1 - 6.3e-13 49.2 0.1 1.1e-12 48.5 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EKG11073.1 - 0.0097 16.0 0.0 0.02 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain CP2 PF04516.10 EKG11073.1 - 0.022 13.7 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 CP2 transcription factor Arf PF00025.16 EKG11073.1 - 0.037 13.2 0.0 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKG11073.1 - 0.074 13.0 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.18 EKG11073.1 - 0.079 11.7 0.0 0.15 10.8 0.0 1.3 1 1 0 1 1 1 0 MCM2/3/5 family Metallophos PF00149.23 EKG11074.1 - 8.1e-12 44.9 0.7 1.8e-11 43.8 0.1 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG11074.1 - 1e-07 31.9 0.2 2.3e-07 30.7 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PI3Ka PF00613.15 EKG11076.1 - 9.6e-60 200.9 0.1 1.5e-59 200.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EKG11076.1 - 1.2e-40 139.5 0.0 3.7e-39 134.5 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EKG11076.1 - 8.8e-31 106.6 0.1 1.6e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DOCK-C2 PF14429.1 EKG11076.1 - 0.00087 18.9 0.2 0.002 17.8 0.0 1.6 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Nse4_C PF08743.5 EKG11077.1 - 2.1e-30 104.5 0.0 5.2e-30 103.3 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EKG11077.1 - 1.2e-15 57.0 0.1 3.5e-15 55.5 0.1 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF2439 PF10382.4 EKG11078.1 - 2.2e-28 98.2 0.0 3.8e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) BAR PF03114.13 EKG11079.1 - 2.7e-14 53.2 4.2 3.8e-14 52.7 2.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EKG11079.1 - 1.3e-13 50.2 0.1 2.3e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG11079.1 - 1.5e-12 46.7 0.1 2.6e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EKG11079.1 - 4.1e-11 42.1 0.0 8.1e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain VIT1 PF01988.14 EKG11079.1 - 0.0057 16.1 0.5 0.012 15.1 0.3 1.4 1 0 0 1 1 1 1 VIT family GAS PF13851.1 EKG11079.1 - 0.011 14.9 7.7 0.017 14.2 5.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EKG11079.1 - 4.4 6.2 8.4 7.8 5.4 5.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Abhydrolase_3 PF07859.8 EKG11081.1 - 6e-17 61.9 0.0 7.3e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG11081.1 - 0.00022 20.0 0.2 0.0003 19.6 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family PRP38 PF03371.10 EKG11083.1 - 2.5e-66 222.5 0.0 3.1e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Parvo_coat_N PF08398.5 EKG11083.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP1 OAD_gamma PF04277.8 EKG11084.1 - 0.049 14.0 1.9 0.06 13.7 0.0 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Pkinase PF00069.20 EKG11085.1 - 1.1e-71 241.0 0.0 1.3e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG11085.1 - 2.6e-38 131.5 0.0 3.4e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG11085.1 - 7.9e-06 25.0 0.0 1.4e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG11085.1 - 0.093 12.4 0.1 0.31 10.7 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Lipase_3 PF01764.20 EKG11086.1 - 7.8e-18 64.4 0.0 1.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 EKG11086.1 - 0.042 12.7 0.1 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 EKG11086.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein 7kD_coat PF02495.12 EKG11086.1 - 0.12 11.8 0.0 0.48 9.9 0.0 2.0 2 0 0 2 2 2 0 7kD viral coat protein AA_permease PF00324.16 EKG11087.1 - 1.8e-22 79.3 2.8 2e-22 79.2 1.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG11087.1 - 2.5e-07 29.5 4.0 2.9e-07 29.3 2.8 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_SspJ PF09575.5 EKG11088.1 - 0.15 12.2 0.2 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) Cwf_Cwc_15 PF04889.7 EKG11089.1 - 2.9e-68 230.2 20.5 3.3e-68 230.0 14.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EKG11089.1 - 0.0012 18.3 9.1 0.0014 18.1 6.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2890 PF11081.3 EKG11089.1 - 0.18 11.8 13.8 0.26 11.3 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) PA26 PF04636.8 EKG11089.1 - 0.42 9.2 4.5 0.48 9.0 3.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SDA1 PF05285.7 EKG11089.1 - 1 8.5 24.2 1.3 8.1 16.8 1.2 1 0 0 1 1 1 0 SDA1 APG6 PF04111.7 EKG11089.1 - 2.7 6.9 9.5 3.7 6.5 6.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 YqfQ PF14181.1 EKG11089.1 - 2.8 7.9 7.4 4.8 7.1 5.1 1.4 1 0 0 1 1 1 0 YqfQ-like protein HNF-1_N PF04814.8 EKG11089.1 - 4.8 7.2 9.3 5.5 7.0 5.7 1.8 2 1 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RNase_PH PF01138.16 EKG11090.1 - 2.2e-22 79.7 0.0 3.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EKG11090.1 - 4.5e-08 32.9 0.0 8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Herpes_pp85 PF04637.7 EKG11090.1 - 0.02 13.2 0.0 0.028 12.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4336 PF14234.1 EKG11091.1 - 6.3e-19 68.2 0.6 7.9e-15 54.7 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) RAI16-like PF10257.4 EKG11092.1 - 2.4e-81 273.4 1.8 2.9e-81 273.1 0.5 1.6 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein CBF PF03914.12 EKG11092.1 - 0.003 17.0 0.3 0.0094 15.4 0.2 1.8 1 1 0 1 1 1 1 CBF/Mak21 family WTF PF03303.8 EKG11093.1 - 0.037 13.4 0.2 0.043 13.2 0.1 1.2 1 0 0 1 1 1 0 WTF protein Fungal_trans PF04082.13 EKG11094.1 - 1.2e-12 47.2 1.4 2.1e-12 46.4 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG11094.1 - 1.4e-05 24.8 14.3 1.4e-05 24.8 9.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF615 PF04751.9 EKG11094.1 - 0.094 12.3 0.4 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF615) DUF2360 PF10152.4 EKG11094.1 - 5.9 7.1 7.8 0.92 9.7 2.2 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Asp PF00026.18 EKG11095.1 - 3.6e-53 180.8 1.4 4.2e-53 180.6 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease RPE65 PF03055.10 EKG11098.1 - 1.8e-66 224.7 0.0 5.2e-34 117.6 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein Mito_carr PF00153.22 EKG11100.1 - 1.2e-47 159.5 6.1 4.9e-17 61.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EKG11101.1 - 3.3e-53 175.7 18.0 1.5e-09 37.3 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EKG11101.1 - 1.1e-10 41.0 0.6 2e-10 40.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EKG11101.1 - 2.5e-07 29.2 6.9 0.034 12.2 0.5 5.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 F-box PF00646.28 EKG11101.1 - 2.4e-05 23.8 0.6 4.8e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EKG11101.1 - 0.0033 16.2 0.3 0.21 10.3 0.0 2.8 1 1 0 2 2 2 1 Nup133 N terminal like CAP_N PF01213.14 EKG11101.1 - 0.026 13.8 4.5 0.041 13.1 3.1 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_61 PF03443.9 EKG11102.1 - 4.8e-16 59.2 0.3 6.2e-16 58.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4382 PF14321.1 EKG11102.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4382) DUF1900 PF08954.6 EKG11103.1 - 4.5e-46 155.7 0.0 3.7e-45 152.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EKG11103.1 - 1.5e-32 111.0 0.0 2.6e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EKG11103.1 - 2.3e-24 84.3 3.8 2.5e-08 33.4 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EKG11103.1 - 0.0071 14.5 0.1 0.026 12.6 0.0 1.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Reo_sigmaC PF04582.7 EKG11103.1 - 0.2 10.8 3.4 0.28 10.3 2.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SlyX PF04102.7 EKG11103.1 - 0.23 11.8 2.6 0.59 10.5 1.8 1.7 1 0 0 1 1 1 0 SlyX Arylsulfotran_2 PF14269.1 EKG11104.1 - 4.4e-30 104.8 0.2 4.4e-30 104.8 0.1 1.9 3 0 0 3 3 3 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EKG11104.1 - 8.9e-08 31.0 2.1 3.6e-07 29.0 1.4 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF605 PF04652.11 EKG11105.1 - 9.5e-05 21.9 10.9 9.5e-05 21.9 7.6 5.4 2 2 3 5 5 5 1 Vta1 like zf-C3HC4_3 PF13920.1 EKG11105.1 - 0.0091 15.6 10.1 0.015 14.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EKG11105.1 - 0.3 10.8 7.0 0.51 10.1 4.8 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EKG11105.1 - 5.6 7.0 12.1 8.9 6.4 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_3 PF07859.8 EKG11106.1 - 9.6e-26 90.6 0.0 1.3e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EKG11106.1 - 2.3e-23 82.4 0.0 2.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EKG11106.1 - 0.00061 18.6 0.1 0.27 9.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EKG11106.1 - 0.0043 16.8 0.1 0.0082 15.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG11106.1 - 0.036 13.2 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ank_2 PF12796.2 EKG11108.1 - 0.013 15.8 0.0 0.042 14.1 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG11108.1 - 0.039 14.4 0.5 4.6 7.8 0.0 3.4 2 1 2 4 4 4 0 Ankyrin repeats (many copies) Chaperone_III PF07824.7 EKG11108.1 - 0.065 13.1 0.1 1.7 8.6 0.1 2.1 2 0 0 2 2 2 0 Type III secretion chaperone domain Ank_3 PF13606.1 EKG11108.1 - 0.088 13.1 0.6 10 6.6 0.0 3.2 3 1 0 3 3 3 0 Ankyrin repeat Ank PF00023.25 EKG11108.1 - 0.18 11.7 0.6 0.56 10.1 0.0 2.3 2 1 0 2 2 2 0 Ankyrin repeat EBP PF05241.7 EKG11109.1 - 2.3e-70 235.5 4.8 2.7e-70 235.3 3.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein Kei1 PF08552.6 EKG11109.1 - 0.088 12.4 2.2 0.13 11.9 0.5 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 CBM_21 PF03370.8 EKG11110.1 - 1.5e-34 118.3 0.4 3.2e-34 117.2 0.3 1.6 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Ssl1 PF04056.9 EKG11111.1 - 7.8e-66 221.3 0.0 1e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EKG11111.1 - 8e-15 54.5 13.0 8e-15 54.5 9.0 3.1 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EKG11111.1 - 1.6e-10 41.3 0.0 2.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKG11111.1 - 0.0029 17.3 0.0 0.0084 15.8 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EKG11111.1 - 0.062 13.0 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain Taeniidae_ag PF05596.6 EKG11111.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Taeniidae antigen SIS_2 PF13580.1 EKG11111.1 - 0.085 12.5 0.1 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 SIS domain Tfb4 PF03850.9 EKG11111.1 - 0.65 9.2 6.8 1.7 7.8 4.7 1.7 1 1 0 1 1 1 0 Transcription factor Tfb4 Chs3p PF12271.3 EKG11112.1 - 1.3e-100 336.2 3.5 1.5e-100 336.0 2.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit V1R PF03402.9 EKG11112.1 - 0.054 12.8 0.8 0.12 11.7 0.5 1.6 1 0 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R Thioredox_DsbH PF03190.10 EKG11113.1 - 5.1e-73 244.1 0.0 7.8e-73 243.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EKG11113.1 - 3.9e-11 42.8 0.0 1.4e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like Glyco_hydro_76 PF03663.9 EKG11113.1 - 0.00013 21.5 0.0 0.00049 19.6 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.8 EKG11113.1 - 0.0045 16.2 2.9 18 4.5 0.0 4.2 3 1 1 4 4 4 1 D-glucuronyl C5-epimerase C-terminus Thioredoxin_2 PF13098.1 EKG11113.1 - 0.0083 16.3 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_hydro_88 PF07470.8 EKG11113.1 - 0.011 14.8 0.1 3 6.7 0.0 3.0 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EKG11113.1 - 0.011 14.0 0.1 1.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) CRT10 PF08728.5 EKG11114.1 - 5.2e-13 47.8 0.0 8.6e-10 37.2 0.0 2.4 2 1 0 2 2 2 2 CRT10 Na_H_Exchanger PF00999.16 EKG11115.1 - 1e-41 142.7 19.3 1.4e-41 142.3 13.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family 7TM_GPCR_Srv PF10323.4 EKG11115.1 - 0.31 10.1 3.0 0.28 10.2 1.0 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Coprogen_oxidas PF01218.13 EKG11116.1 - 2.7e-134 446.3 0.1 3e-134 446.2 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Peptidase_M1 PF01433.15 EKG11117.1 - 2.8e-135 451.3 3.9 4.5e-135 450.6 2.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EKG11117.1 - 1.8e-78 264.0 0.0 3.1e-78 263.2 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EKG11117.1 - 2e-21 76.3 1.5 5e-21 75.0 0.1 2.2 1 1 1 2 2 2 1 Peptidase MA superfamily PEX11 PF05648.9 EKG11118.1 - 7e-32 110.5 0.1 1.2e-31 109.7 0.1 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4612 PF15389.1 EKG11118.1 - 0.007 16.9 0.5 0.011 16.2 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4612) UPF0075 PF03702.9 EKG11120.1 - 2.9e-77 260.0 0.0 3.3e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Sugar_tr PF00083.19 EKG11121.1 - 9.6e-82 274.9 18.6 1.2e-81 274.6 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11121.1 - 2.9e-26 92.0 38.3 1.6e-24 86.3 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Keratin_assoc PF09775.4 EKG11121.1 - 0.057 12.9 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 TPR_4 PF07721.9 EKG11121.1 - 0.11 12.9 1.5 1.2 9.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3792 PF12670.2 EKG11121.1 - 0.46 10.3 15.9 0.056 13.3 5.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) TPR_16 PF13432.1 EKG11121.1 - 0.46 11.2 7.2 0.12 13.0 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EKG11122.1 - 3.1e-07 29.5 0.1 4.5e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cutinase PF01083.17 EKG11124.1 - 2.5e-08 33.8 0.0 2.8e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase PetG PF02529.10 EKG11124.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Mus7 PF09462.5 EKG11125.1 - 1.4e-148 496.5 4.0 2e-148 496.0 2.4 1.6 2 0 0 2 2 2 1 Mus7/MMS22 family DUF3315 PF11776.3 EKG11125.1 - 0.0092 15.4 0.8 0.022 14.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3315) Glu-tRNAGln PF02686.10 EKG11127.1 - 0.0003 20.5 0.1 0.0014 18.4 0.1 2.0 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit DUF2992 PF11208.3 EKG11127.1 - 0.042 13.7 0.2 0.068 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SNAP PF14938.1 EKG11128.1 - 2e-112 374.9 15.9 2.2e-112 374.8 11.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EKG11128.1 - 1.6e-06 27.9 13.3 0.005 16.7 1.9 3.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKG11128.1 - 2.2e-05 24.0 16.8 0.61 10.1 0.0 6.5 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG11128.1 - 7e-05 22.3 10.7 2.3 8.1 0.2 6.0 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKG11128.1 - 0.0013 18.3 17.4 0.035 13.7 3.3 3.7 1 1 3 4 4 4 3 TPR repeat TRAPPC-Trs85 PF12739.2 EKG11128.1 - 0.0069 15.0 4.8 0.017 13.7 3.3 1.7 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_6 PF13174.1 EKG11128.1 - 0.009 16.4 13.5 7.6 7.2 0.0 6.3 4 1 1 6 6 5 1 Tetratricopeptide repeat Prenylcys_lyase PF07156.9 EKG11128.1 - 0.03 13.2 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Prenylcysteine lyase TPR_16 PF13432.1 EKG11128.1 - 0.076 13.7 19.4 0.17 12.5 1.4 4.2 2 1 3 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKG11128.1 - 0.29 10.8 18.4 1.3 8.7 0.1 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKG11128.1 - 0.58 10.0 12.0 4.3 7.3 0.1 5.5 4 1 3 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG11128.1 - 1.5 9.7 16.0 4.5 8.1 0.6 5.5 3 1 4 7 7 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EKG11128.1 - 3.5 7.5 9.9 22 4.9 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF726 PF05277.7 EKG11129.1 - 5.1e-119 397.2 2.5 6.9e-119 396.7 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EKG11129.1 - 7.9e-05 22.6 0.5 0.00025 21.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EKG11129.1 - 0.00033 20.9 0.0 0.00033 20.9 0.0 2.4 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_5 PF12695.2 EKG11129.1 - 0.00077 19.2 0.4 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.17 EKG11129.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.15 EKG11129.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PE-PPE PF08237.6 EKG11129.1 - 0.2 11.0 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain PV-1 PF06637.6 EKG11129.1 - 0.21 10.1 14.3 0.21 10.1 0.1 2.5 2 0 0 2 2 2 0 PV-1 protein (PLVAP) V-SNARE PF05008.10 EKG11130.1 - 2.3e-21 75.7 3.1 2.3e-21 75.7 2.1 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EKG11130.1 - 6.5e-17 61.3 4.9 6.5e-17 61.3 3.4 2.8 4 0 0 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EKG11130.1 - 0.0052 16.4 1.0 0.013 15.1 0.1 2.1 2 1 1 3 3 3 1 Sec20 RRF PF01765.14 EKG11130.1 - 0.037 13.4 1.1 0.072 12.5 0.8 1.6 1 1 0 1 1 1 0 Ribosome recycling factor Synaptobrevin PF00957.16 EKG11130.1 - 0.037 13.6 3.1 0.097 12.2 0.1 2.9 3 0 0 3 3 3 0 Synaptobrevin DUF1542 PF07564.6 EKG11130.1 - 0.094 12.7 2.2 0.15 12.0 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Use1 PF09753.4 EKG11130.1 - 0.15 11.4 4.9 1.1 8.6 3.4 2.2 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF4332 PF14229.1 EKG11130.1 - 0.47 10.4 3.7 0.38 10.7 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4332) V_ATPase_I PF01496.14 EKG11130.1 - 0.5 8.1 4.6 0.41 8.4 2.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family HK97-gp10_like PF04883.7 EKG11130.1 - 0.9 10.5 5.1 5.8 7.9 1.6 2.9 2 2 1 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component Seryl_tRNA_N PF02403.17 EKG11130.1 - 1.7 8.7 8.2 3 7.9 0.0 3.5 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 EKG11130.1 - 1.8 8.3 10.7 0.17 11.7 1.7 2.5 1 1 1 2 2 2 0 Tropomyosin like Mnd1 PF03962.10 EKG11130.1 - 3.9 7.1 8.7 0.75 9.4 1.0 2.3 1 1 1 2 2 2 0 Mnd1 family TBCA PF02970.11 EKG11130.1 - 4.1 7.5 9.2 0.28 11.2 1.2 2.5 3 1 0 3 3 3 0 Tubulin binding cofactor A NAD_binding_8 PF13450.1 EKG11131.1 - 8e-14 51.4 0.0 1.7e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EKG11131.1 - 1.4e-10 40.8 0.1 4.9e-08 32.4 0.0 3.0 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EKG11131.1 - 3.5e-06 27.2 0.0 0.013 15.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG11131.1 - 2.4e-05 23.4 0.2 0.00052 19.0 0.1 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG11131.1 - 5.9e-05 22.8 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EKG11131.1 - 0.0004 20.7 0.0 0.006 16.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG11131.1 - 0.022 14.6 0.0 0.087 12.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cnl2_NKP2 PF09447.5 EKG11132.1 - 2.7e-25 87.8 1.1 3.8e-25 87.3 0.0 1.8 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Glyco_hydro_20 PF00728.17 EKG11132.1 - 0.00074 18.7 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Tudor-knot PF11717.3 EKG11133.1 - 2.5e-08 33.5 2.7 2.8e-08 33.3 0.9 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EKG11133.1 - 0.0013 18.3 1.1 0.0029 17.2 0.8 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_S49_N PF08496.5 EKG11133.1 - 0.0092 15.7 5.7 0.043 13.6 1.1 2.1 2 0 0 2 2 2 1 Peptidase family S49 N-terminal RIC3 PF15361.1 EKG11133.1 - 0.043 14.0 1.2 0.043 14.0 0.9 1.7 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 GAGA_bind PF06217.7 EKG11133.1 - 4.3 7.1 11.0 0.39 10.6 3.9 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 EKG11133.1 - 7.3 5.6 10.8 1.3 8.1 4.2 1.8 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DUF4613 PF15390.1 EKG11133.1 - 8.9 4.3 6.3 7 4.6 3.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4613) MRG PF05712.8 EKG11134.1 - 2e-49 167.1 0.1 2.2e-49 166.9 0.1 1.0 1 0 0 1 1 1 1 MRG PMBR PF09373.5 EKG11134.1 - 0.27 11.2 1.7 22 5.2 0.1 3.1 3 0 0 3 3 3 0 Pseudomurein-binding repeat Cyclase PF04199.8 EKG11136.1 - 3.1e-14 53.0 0.0 4.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase GMC_oxred_N PF00732.14 EKG11137.1 - 1.6e-59 201.5 0.0 1.9e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG11137.1 - 2.5e-32 112.1 0.1 4.7e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EKG11137.1 - 0.00029 19.8 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG11137.1 - 0.00052 19.9 0.6 0.0051 16.7 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG11137.1 - 0.001 18.0 0.1 0.002 17.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG11137.1 - 0.0011 18.8 0.0 0.0054 16.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG11137.1 - 0.0041 16.2 0.1 0.007 15.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EKG11137.1 - 0.0065 15.3 0.9 0.012 14.5 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EKG11137.1 - 0.055 11.9 0.1 0.084 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein WD40 PF00400.27 EKG11138.1 - 1.5e-17 62.7 6.8 2e-06 27.4 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat RR_TM4-6 PF06459.7 EKG11138.1 - 1.9 8.3 7.2 3.4 7.4 5.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AMP-binding PF00501.23 EKG11139.1 - 1.5e-89 300.3 0.1 1.8e-89 300.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG11139.1 - 1.6e-22 80.2 0.2 8.1e-20 71.5 0.1 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.1 EKG11140.1 - 4.4e-60 202.9 12.6 4.4e-60 202.9 8.7 2.3 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EKG11140.1 - 2.1e-47 161.3 5.6 3.8e-47 160.4 3.9 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EKG11140.1 - 2.5e-47 161.1 6.7 4.9e-47 160.2 4.6 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EKG11140.1 - 2e-19 69.5 32.0 2e-19 69.5 22.2 4.9 2 2 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.1 EKG11140.1 - 2.2e-19 70.1 0.7 6.3e-19 68.7 0.5 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 EKG11140.1 - 0.0033 17.2 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide SKG6 PF08693.5 EKG11140.1 - 0.025 13.8 0.9 0.075 12.3 0.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C2H2_4 PF13894.1 EKG11141.1 - 9.8e-13 47.4 21.9 0.0034 17.5 0.2 5.7 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EKG11141.1 - 3.3e-12 46.1 18.3 1.7e-06 28.0 1.0 5.4 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EKG11141.1 - 2.2e-09 37.0 28.6 0.035 14.4 0.4 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EKG11141.1 - 1.4e-08 34.5 17.5 8.6e-06 25.7 1.0 4.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EKG11141.1 - 1.6e-05 24.9 14.7 0.065 13.3 0.1 4.7 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EKG11141.1 - 0.0065 16.1 1.4 4.7 7.0 0.0 3.2 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EKG11141.1 - 0.013 15.4 22.4 1.2 9.1 0.8 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG11141.1 - 0.086 13.1 25.3 0.2 12.0 0.9 5.5 5 1 0 5 5 5 0 Zinc-finger double domain zf-DBF PF07535.7 EKG11141.1 - 0.43 10.2 15.0 0.1 12.3 2.7 3.5 2 1 2 4 4 4 0 DBF zinc finger Rpr2 PF04032.11 EKG11141.1 - 0.69 9.8 4.9 0.95 9.3 2.1 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1764 PF08576.5 EKG11141.1 - 0.69 10.7 5.7 1.4 9.7 4.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Cellulase PF00150.13 EKG11142.1 - 2e-55 187.9 0.9 2.7e-55 187.5 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AAA PF00004.24 EKG11143.1 - 1.8e-41 141.4 0.0 2.7e-38 131.1 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG11143.1 - 5.7e-05 23.9 0.3 0.0012 19.6 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EKG11143.1 - 8.7e-05 22.6 0.2 0.0073 16.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG11143.1 - 0.0001 22.3 1.5 0.0069 16.3 0.0 3.8 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EKG11143.1 - 0.00017 20.6 0.0 0.00071 18.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EKG11143.1 - 0.00037 19.3 0.0 0.00074 18.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EKG11143.1 - 0.00049 20.0 0.5 0.0049 16.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EKG11143.1 - 0.0023 17.6 1.5 0.011 15.4 0.3 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EKG11143.1 - 0.0066 16.1 0.0 0.019 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EKG11143.1 - 0.0085 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EKG11143.1 - 0.0097 15.8 0.1 0.04 13.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EKG11143.1 - 0.012 15.5 0.0 0.057 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EKG11143.1 - 0.023 13.8 0.1 0.046 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EKG11143.1 - 0.028 14.7 0.0 0.087 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKG11143.1 - 0.033 14.0 0.0 0.12 12.2 0.0 2.0 1 1 1 2 2 1 0 AAA domain AAA_24 PF13479.1 EKG11143.1 - 0.04 13.4 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKG11143.1 - 0.046 13.1 0.2 0.96 8.8 0.2 2.8 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 EKG11143.1 - 0.046 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EKG11143.1 - 0.068 13.2 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.11 EKG11143.1 - 0.1 11.7 0.0 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase SHQ1 PF04925.10 EKG11143.1 - 0.21 11.0 0.0 0.45 9.9 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein Parvo_NS1 PF01057.12 EKG11143.1 - 0.4 9.4 0.0 0.7 8.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 BING4CT PF08149.6 EKG11144.1 - 6.4e-42 140.9 0.0 2.1e-38 129.6 0.0 3.1 4 0 0 4 4 4 2 BING4CT (NUC141) domain WD40 PF00400.27 EKG11144.1 - 2.8e-06 26.9 0.0 0.00067 19.4 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat eIF2A PF08662.6 EKG11144.1 - 0.052 13.2 0.0 0.38 10.4 0.0 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 EKG11145.1 - 2.6e-24 86.0 0.0 4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11145.1 - 1.8e-21 77.0 0.0 2.3e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG11145.1 - 5.2e-08 32.7 0.0 9.1e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 KR domain SnoaL_2 PF12680.2 EKG11146.1 - 4.4e-09 36.6 0.0 5.4e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EKG11146.1 - 7.4e-06 25.8 0.0 9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EKG11146.1 - 0.00042 20.4 0.0 0.00061 19.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EKG11146.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain SnoaL PF07366.7 EKG11146.1 - 0.029 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase FAD_binding_4 PF01565.18 EKG11147.1 - 2.6e-22 78.7 0.1 3.4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DUF4396 PF14342.1 EKG11148.1 - 5.7e-11 42.6 0.1 8e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) HET PF06985.6 EKG11150.1 - 0.0072 16.4 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) L51_S25_CI-B8 PF05047.11 EKG11152.1 - 7.1e-13 48.0 0.0 1.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF4448 PF14610.1 EKG11154.1 - 1.2e-08 34.6 0.0 2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) PTH2 PF01981.11 EKG11155.1 - 2.2e-45 153.0 0.1 3.1e-45 152.5 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Treacle PF03546.9 EKG11155.1 - 0.013 14.3 0.2 0.018 13.8 0.1 1.3 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle BLVR PF06375.6 EKG11155.1 - 0.052 13.3 2.5 0.086 12.6 1.7 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Ribosomal_60s PF00428.14 EKG11155.1 - 2.4 8.6 7.8 5.6 7.4 5.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_L28 PF00830.14 EKG11156.1 - 4.1e-21 74.5 1.1 6.5e-21 73.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal L28 family SART-1 PF03343.8 EKG11157.1 - 1.3e-157 525.8 62.2 1.5e-157 525.6 43.1 1.0 1 0 0 1 1 1 1 SART-1 family HET PF06985.6 EKG11158.1 - 5.5e-21 75.1 0.0 1.1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lyase_aromatic PF00221.14 EKG11159.1 - 8e-134 446.6 5.7 1.3e-133 445.9 3.9 1.3 1 0 0 1 1 1 1 Aromatic amino acid lyase DNA_binding_1 PF01035.15 EKG11160.1 - 1.6e-20 72.6 0.0 2.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain adh_short PF00106.20 EKG11161.1 - 5.2e-27 94.7 0.0 7.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11161.1 - 8.3e-21 74.8 0.0 1e-20 74.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG11161.1 - 2.1e-06 27.5 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG11161.1 - 5.4e-05 23.2 0.1 0.00017 21.6 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EKG11161.1 - 0.0002 20.8 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EKG11161.1 - 0.0076 15.7 0.0 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EKG11161.1 - 0.009 15.7 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EKG11161.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EKG11162.1 - 1.5e-16 60.8 0.0 2.3e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11162.1 - 1e-08 35.2 0.0 1.4e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG11162.1 - 0.00012 22.1 0.0 0.00027 21.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG11162.1 - 0.00056 19.6 0.0 0.0094 15.6 0.0 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG11162.1 - 0.00059 19.3 0.0 0.0011 18.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EKG11162.1 - 0.04 13.4 0.0 0.57 9.7 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EKG11162.1 - 0.093 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain UPF0146 PF03686.8 EKG11162.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Glyco_transf_34 PF05637.7 EKG11163.1 - 4.9e-60 203.0 0.0 8e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EKG11163.1 - 0.014 14.7 0.0 2 7.7 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF273 PMI_typeI PF01238.16 EKG11164.1 - 1.2e-76 258.1 0.0 1.2e-75 254.8 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EKG11164.1 - 0.00058 19.2 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EKG11164.1 - 0.012 15.2 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain Diphthamide_syn PF01866.12 EKG11165.1 - 2e-95 319.5 0.0 8.3e-78 261.7 0.0 2.9 2 1 0 2 2 2 2 Putative diphthamide synthesis protein HMGL-like PF00682.14 EKG11166.1 - 2.1e-38 132.3 0.0 6.2e-30 104.6 0.1 2.1 2 0 0 2 2 2 2 HMGL-like DUF1751 PF08551.5 EKG11167.1 - 1.5e-21 76.5 0.4 2.2e-21 76.0 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) LisH PF08513.6 EKG11168.1 - 2.1e-05 24.1 0.2 3.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EKG11168.1 - 4.1e-05 23.2 0.1 0.13 12.1 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.7 EKG11168.1 - 0.084 12.5 0.0 8.8 6.1 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Pyr_redox_3 PF13738.1 EKG11169.1 - 3.8e-23 82.6 0.0 1.3e-22 80.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG11169.1 - 1.6e-10 40.4 0.0 4.2e-08 32.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EKG11169.1 - 3.1e-08 32.2 0.0 1.3e-07 30.2 0.0 2.0 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG11169.1 - 1.9e-07 30.9 0.0 5.3e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG11169.1 - 6.7e-05 21.9 0.3 0.16 10.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG11169.1 - 7.5e-05 22.5 0.2 0.0047 16.7 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG11169.1 - 7.8e-05 22.6 0.0 0.0023 17.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG11169.1 - 0.026 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EKG11169.1 - 0.03 12.8 0.1 0.044 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DEDD_Tnp_IS110 PF01548.12 EKG11169.1 - 0.13 11.9 0.0 0.39 10.3 0.0 1.7 2 0 0 2 2 2 0 Transposase AIG2 PF06094.7 EKG11170.1 - 7.9e-10 39.1 0.2 2.3e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 AIG2-like family GST_N_3 PF13417.1 EKG11170.1 - 0.053 13.7 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.19 EKG11171.1 - 2.5e-95 319.6 24.1 3.1e-95 319.4 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11171.1 - 4.7e-20 71.5 35.4 6.7e-16 57.9 10.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.7 EKG11172.1 - 5.8e-08 33.1 0.0 8.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG11172.1 - 4.4e-06 26.3 0.0 5.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG11172.1 - 1.7e-05 25.3 0.0 2.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG11172.1 - 6.7e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG11172.1 - 0.0005 20.3 0.0 0.00081 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG11172.1 - 0.034 14.6 0.0 0.053 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Avirulence PF03377.8 EKG11173.1 - 0.098 11.3 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA Imm5 PF14423.1 EKG11174.1 - 0.0072 15.9 0.1 0.0084 15.7 0.0 1.0 1 0 0 1 1 1 1 Immunity protein Imm5 YfcL PF08891.6 EKG11174.1 - 0.018 14.9 0.7 0.15 12.0 0.1 2.1 1 1 1 2 2 2 0 YfcL protein DUF3384 PF11864.3 EKG11174.1 - 0.043 12.2 0.1 0.05 12.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) APG6 PF04111.7 EKG11174.1 - 0.048 12.7 1.0 0.056 12.4 0.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 ImcF-related_N PF14331.1 EKG11174.1 - 0.064 12.1 1.9 0.069 12.0 1.3 1.0 1 0 0 1 1 1 0 ImcF-related N-terminal domain PilJ PF13675.1 EKG11174.1 - 0.18 12.1 2.2 0.22 11.8 1.5 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term NYD-SP28_assoc PF14775.1 EKG11174.1 - 0.2 11.3 0.3 0.2 11.3 0.2 1.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain NACHT PF05729.7 EKG11175.1 - 2.2e-06 27.4 0.2 5.8e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ank_2 PF12796.2 EKG11175.1 - 0.00024 21.4 0.0 0.01 16.1 0.0 3.2 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKG11175.1 - 0.01 15.5 0.1 7.7 6.5 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Ank_3 PF13606.1 EKG11175.1 - 0.018 15.2 0.0 54 4.4 0.0 4.4 4 1 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.1 EKG11175.1 - 0.021 15.0 0.1 2.1 8.6 0.0 3.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG11175.1 - 0.039 14.4 0.0 1.4 9.4 0.0 2.8 1 1 1 2 2 2 0 Ankyrin repeats (many copies) AAA_22 PF13401.1 EKG11175.1 - 0.11 12.6 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ACBP PF00887.14 EKG11176.1 - 1.4e-27 95.1 0.0 2.3e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein TipAS PF07739.8 EKG11176.1 - 1.5 9.1 6.1 0.65 10.3 0.5 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Spc97_Spc98 PF04130.8 EKG11177.1 - 2.7e-130 435.2 0.1 3.3e-130 434.9 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GATase_6 PF13522.1 EKG11178.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain Fer2_3 PF13085.1 EKG11179.1 - 0.058 13.2 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Peptidase_S41 PF03572.13 EKG11180.1 - 1.6e-09 37.3 0.0 7.6e-09 35.1 0.0 2.1 2 1 0 2 2 2 1 Peptidase family S41 FAD_binding_3 PF01494.14 EKG11182.1 - 3.9e-08 32.7 0.0 5.8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FYRC PF05965.9 EKG11183.1 - 0.061 13.1 0.0 0.095 12.5 0.0 1.3 1 0 0 1 1 1 0 F/Y rich C-terminus Met_synt_B12 PF02965.12 EKG11184.1 - 0.07 12.3 1.3 0.085 12.0 0.9 1.1 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Curto_V2 PF07325.6 EKG11184.1 - 1.3 8.6 4.2 1.5 8.4 2.9 1.1 1 0 0 1 1 1 0 Curtovirus V2 protein DUF1168 PF06658.7 EKG11184.1 - 2.2 7.8 21.1 3.4 7.1 14.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Nop25 PF09805.4 EKG11184.1 - 4.4 7.3 22.4 5.6 7.0 15.5 1.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3317 PF11779.3 EKG11185.1 - 5.6e-24 83.3 2.7 1e-23 82.5 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) SieB PF14163.1 EKG11185.1 - 0.008 15.7 0.9 0.008 15.7 0.6 1.4 1 1 0 1 1 1 1 Superinfection exclusion protein B PrgI PF12666.2 EKG11185.1 - 1.8 8.7 5.9 0.5 10.5 0.9 2.0 1 1 1 2 2 2 0 PrgI family protein AAA_2 PF07724.9 EKG11186.1 - 1.7e-39 135.4 0.0 5.7e-39 133.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EKG11186.1 - 4.3e-15 56.0 0.0 8.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EKG11186.1 - 5.6e-11 42.1 0.0 1.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EKG11186.1 - 1.4e-07 31.3 0.0 3.8e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKG11186.1 - 1.7e-05 24.8 1.1 0.00045 20.2 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG11186.1 - 4e-05 23.7 0.7 0.0013 18.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EKG11186.1 - 9.8e-05 21.6 0.8 0.013 14.6 0.1 3.1 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EKG11186.1 - 0.00049 20.9 0.2 0.0014 19.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EKG11186.1 - 0.0011 18.4 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EKG11186.1 - 0.0016 17.9 0.0 0.091 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 EKG11186.1 - 0.0026 16.8 0.1 0.072 12.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus BNIP3 PF06553.7 EKG11186.1 - 0.0046 16.3 0.9 0.011 15.1 0.6 1.5 1 0 0 1 1 1 1 BNIP3 AAA_24 PF13479.1 EKG11186.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKG11186.1 - 0.0091 15.8 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EKG11186.1 - 0.029 13.9 0.0 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EKG11186.1 - 0.033 14.4 0.1 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EKG11186.1 - 0.043 14.0 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PsbU PF06514.6 EKG11186.1 - 0.053 13.3 0.0 18 5.2 0.0 2.8 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) AAA_25 PF13481.1 EKG11186.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EKG11186.1 - 0.063 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family NACHT PF05729.7 EKG11186.1 - 0.069 12.8 0.2 0.56 9.8 0.2 2.2 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EKG11186.1 - 0.46 10.7 0.0 0.46 10.7 0.0 1.9 3 0 0 3 3 1 0 AAA domain Alpha-amylase_C PF02806.13 EKG11187.1 - 1.2e-25 89.5 0.2 5e-25 87.4 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EKG11187.1 - 3.5e-18 66.0 0.1 9.5e-14 51.5 0.2 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EKG11187.1 - 8.4e-14 51.3 0.0 2.3e-13 49.9 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) ATP-synt_ab PF00006.20 EKG11188.1 - 2.7e-62 210.0 0.0 3.9e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EKG11188.1 - 3.4e-25 88.7 0.5 5.8e-25 87.9 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EKG11188.1 - 9.8e-25 86.5 0.8 3.6e-24 84.7 0.3 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EKG11188.1 - 0.0028 16.8 0.2 0.0047 16.0 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA PF00004.24 EKG11188.1 - 0.0048 17.0 0.2 0.55 10.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EKG11188.1 - 0.012 15.0 0.1 0.045 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EKG11188.1 - 0.026 13.6 0.1 0.048 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EKG11188.1 - 0.027 14.1 0.2 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EKG11188.1 - 0.028 14.0 0.2 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EKG11188.1 - 0.037 14.0 0.5 0.31 10.9 0.3 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EKG11188.1 - 0.085 13.0 0.1 0.33 11.1 0.0 2.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EKG11188.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EKG11188.1 - 0.098 11.4 0.7 0.58 8.9 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EKG11188.1 - 0.11 12.2 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase CENP-I PF07778.6 EKG11189.1 - 1.7e-92 310.2 0.0 2.5e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 Mis6 GFA PF04828.9 EKG11191.1 - 5.6e-18 64.6 0.2 7.6e-18 64.2 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF2012 PF09430.5 EKG11192.1 - 2.7e-15 56.2 0.0 3.7e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EKG11192.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain CLPTM1 PF05602.7 EKG11193.1 - 2.2e-161 537.4 0.0 2.9e-161 537.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1673 PF07895.6 EKG11193.1 - 0.015 14.7 3.9 0.039 13.4 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) 2TM PF13239.1 EKG11193.1 - 3.8 7.6 7.8 0.75 9.9 1.0 3.1 3 1 1 4 4 4 0 2TM domain Lysine_decarbox PF03641.9 EKG11194.1 - 1.2e-29 102.7 0.1 1.6e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase FA_desaturase PF00487.19 EKG11195.1 - 6.9e-27 94.5 14.2 1e-26 93.9 9.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EKG11195.1 - 6.1e-08 32.7 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) CAP PF00188.21 EKG11196.1 - 8.3e-15 55.3 4.6 8.3e-15 55.3 3.2 2.3 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF3684 PF12449.3 EKG11197.1 - 0 1064.9 0.0 0 1064.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EKG11197.1 - 0.00034 20.2 0.0 0.00098 18.7 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKG11197.1 - 0.0053 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAPPC9-Trs120 PF08626.6 EKG11198.1 - 1.1e-76 258.1 0.0 1.2e-50 171.9 0.0 3.0 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CAS_CSE1 PF03378.10 EKG11199.1 - 6.3e-176 584.9 0.3 2.6e-175 582.9 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EKG11199.1 - 1.6e-152 507.4 2.2 2.2e-152 506.9 1.6 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EKG11199.1 - 7.6e-14 51.3 1.8 1.9e-13 50.1 0.1 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain iPGM_N PF06415.8 EKG11199.1 - 0.0063 15.8 0.1 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) DUF1529 PF07485.6 EKG11199.1 - 0.035 13.8 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) Xpo1 PF08389.7 EKG11199.1 - 0.049 13.5 1.1 0.83 9.5 0.0 3.7 5 0 0 5 5 5 0 Exportin 1-like protein DUF3384 PF11864.3 EKG11200.1 - 4.9e-62 209.9 2.5 1.3e-60 205.2 1.7 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EKG11200.1 - 3.4e-54 183.1 0.0 1.2e-53 181.2 0.0 1.9 2 0 0 2 2 2 1 Rap/ran-GAP Tuberin PF03542.11 EKG11200.1 - 4.2e-29 101.7 0.5 2.2e-25 89.5 0.1 2.5 2 0 0 2 2 2 2 Tuberin SAE2 PF08573.5 EKG11201.1 - 1.8e-24 86.2 0.1 1.8e-23 83.0 0.1 2.9 1 0 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Hemerythrin PF01814.18 EKG11201.1 - 1.8e-05 24.9 0.6 7.3e-05 22.9 0.1 2.3 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain F-box-like PF12937.2 EKG11202.1 - 6.9e-10 38.4 1.1 1.4e-09 37.5 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG11202.1 - 1.8e-09 37.0 0.4 3.7e-09 36.0 0.3 1.5 1 0 0 1 1 1 1 F-box domain zf-CCHC PF00098.18 EKG11203.1 - 6.9e-53 174.1 58.2 3e-09 36.3 0.8 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EKG11203.1 - 1.4e-12 47.0 42.5 0.044 13.4 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EKG11203.1 - 1.2e-05 24.9 48.6 0.046 13.4 0.4 6.8 3 2 4 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 EKG11203.1 - 2.1e-05 24.1 40.4 0.056 13.1 1.2 6.7 4 2 3 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 EKG11203.1 - 0.24 10.9 0.2 0.24 10.9 0.1 7.0 3 2 4 7 7 7 0 Zinc knuckle Arylsulfotran_2 PF14269.1 EKG11204.1 - 3.3e-55 187.3 1.5 4.2e-55 187.0 1.0 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EKG11204.1 - 2.7e-15 55.8 1.0 7.9e-15 54.3 0.7 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Abhydrolase_2 PF02230.11 EKG11204.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase OAD_gamma PF04277.8 EKG11205.1 - 0.039 14.3 0.1 0.039 14.3 0.1 1.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain RNase_HII PF01351.13 EKG11206.1 - 2.9e-46 157.6 0.0 3.7e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Peptidase_M28 PF04389.12 EKG11208.1 - 2.8e-34 118.4 0.2 6.4e-34 117.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EKG11208.1 - 2.6e-11 43.0 0.1 2.6e-11 43.0 0.1 2.5 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.23 EKG11208.1 - 0.00018 21.0 0.1 0.0036 16.8 0.1 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Choline_transpo PF04515.7 EKG11209.1 - 1.6e-14 53.4 15.5 1.6e-14 53.4 10.7 3.0 3 0 0 3 3 3 2 Plasma-membrane choline transporter Ras PF00071.17 EKG11210.1 - 3.7e-38 130.4 0.1 5e-38 130.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG11210.1 - 3.4e-11 43.6 0.0 6.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG11210.1 - 1.3e-08 34.2 0.1 2.6e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG11210.1 - 1e-06 28.2 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKG11210.1 - 0.00034 19.8 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EKG11211.1 - 1.5e-63 213.0 0.2 1.8e-63 212.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG11211.1 - 5.7e-22 78.4 0.1 8.6e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG11211.1 - 2.4e-13 49.6 0.1 3.1e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKG11211.1 - 3.2e-08 33.5 0.1 5.3e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG11211.1 - 3.7e-05 23.2 0.1 0.00013 21.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKG11211.1 - 5.8e-05 22.3 0.1 9.9e-05 21.5 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKG11211.1 - 8.6e-05 22.6 0.1 0.0003 20.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EKG11211.1 - 0.0011 18.9 0.1 0.0028 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EKG11211.1 - 0.0016 17.5 0.0 0.0022 17.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EKG11211.1 - 0.0028 16.8 0.1 0.0065 15.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EKG11211.1 - 0.0062 16.4 0.1 0.084 12.8 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EKG11211.1 - 0.0097 15.1 0.0 0.017 14.3 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EKG11211.1 - 0.017 15.0 0.7 0.057 13.4 0.5 2.0 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EKG11211.1 - 0.017 15.3 0.4 0.028 14.6 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EKG11211.1 - 0.018 14.6 0.2 0.031 13.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EKG11211.1 - 0.081 12.2 0.1 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EKG11211.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EKG11211.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF840 PF05801.6 EKG11212.1 - 0.024 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) Arm PF00514.18 EKG11213.1 - 8.5e-13 47.6 9.7 0.00035 20.2 0.0 8.4 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EKG11213.1 - 0.03 14.3 11.2 2.8 8.2 0.1 5.5 5 0 0 5 5 5 0 HEAT repeat Cyclin PF08613.6 EKG11215.1 - 7.9e-28 97.7 0.1 1.3e-27 97.0 0.1 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EKG11215.1 - 3e-05 23.5 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupredoxin_1 PF13473.1 EKG11216.1 - 1.4e-05 24.8 0.1 2.9e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Cupredoxin-like domain DUF947 PF06102.7 EKG11217.1 - 2.2e-52 177.2 29.5 2.2e-52 177.2 20.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Glu_syn_central PF04898.9 EKG11217.1 - 0.23 10.6 5.0 0.073 12.3 0.6 1.9 2 0 0 2 2 2 0 Glutamate synthase central domain gag-asp_proteas PF13975.1 EKG11218.1 - 0.00077 19.2 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EKG11218.1 - 0.0035 17.7 0.0 0.0076 16.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EKG11218.1 - 0.14 12.0 0.0 0.66 9.9 0.0 2.2 1 1 0 1 1 1 0 Retroviral aspartyl protease DUF1265 PF06887.9 EKG11220.1 - 0.054 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) Cyclase PF04199.8 EKG11221.1 - 3.9e-11 42.9 0.0 6.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase SUI1 PF01253.17 EKG11222.1 - 8.3e-16 57.5 0.0 1.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 EKG11222.1 - 0.0099 15.5 0.0 0.035 13.8 0.0 1.9 1 0 0 1 1 1 1 PUA domain Pex14_N PF04695.8 EKG11222.1 - 0.014 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SNARE PF05739.14 EKG11224.1 - 3.1e-10 39.6 2.1 4.2e-10 39.1 1.5 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EKG11224.1 - 0.003 17.0 0.0 0.003 17.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 RNA12 PF10443.4 EKG11225.1 - 2.3e-172 573.3 0.3 3.1e-172 572.9 0.2 1.1 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EKG11225.1 - 5.7e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EKG11225.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG11225.1 - 0.0079 16.1 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.1 EKG11225.1 - 0.0094 15.9 2.5 0.073 13.0 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain RRM_5 PF13893.1 EKG11225.1 - 0.014 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EKG11225.1 - 0.015 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) AAA_14 PF13173.1 EKG11225.1 - 0.093 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3767 PF12597.3 EKG11226.1 - 0.11 12.1 0.2 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) BTB PF00651.26 EKG11227.1 - 2.4e-06 27.4 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain VEFS-Box PF09733.4 EKG11229.1 - 5.8e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 VEFS-Box of polycomb protein TipAS PF07739.8 EKG11229.1 - 0.043 14.1 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain F-box-like PF12937.2 EKG11230.1 - 3.3e-07 29.9 0.2 9.9e-07 28.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG11230.1 - 0.053 13.1 2.2 0.095 12.3 0.0 2.7 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.2 EKG11230.1 - 0.23 11.1 9.0 0.33 10.6 0.1 3.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EKG11230.1 - 0.66 10.2 3.1 80 3.7 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich repeat WW PF00397.21 EKG11231.1 - 2.7e-08 33.4 0.4 6.2e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 WW domain Mito_carr PF00153.22 EKG11233.1 - 4e-31 106.5 1.6 8e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CHZ PF09649.5 EKG11234.1 - 4.6e-18 64.1 2.5 4.6e-18 64.1 1.7 1.8 2 0 0 2 2 2 1 Histone chaperone domain CHZ Glu_synthase PF01645.12 EKG11235.1 - 3.2e-160 533.0 0.1 4.3e-159 529.3 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EKG11235.1 - 4.2e-138 459.9 0.0 6.1e-138 459.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EKG11235.1 - 9.2e-120 399.2 0.0 1.6e-119 398.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EKG11235.1 - 7.9e-68 227.4 2.0 1.6e-67 226.4 1.4 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EKG11235.1 - 6.2e-23 80.5 0.1 1.5e-22 79.3 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EKG11235.1 - 1e-16 61.4 0.0 5.9e-16 58.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG11235.1 - 5.8e-12 46.1 0.3 4.9e-05 23.4 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG11235.1 - 3.9e-09 36.4 0.1 1.5e-08 34.4 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG11235.1 - 6.1e-08 32.9 0.0 0.00026 21.3 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EKG11235.1 - 1.6e-06 27.5 0.1 2.7e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EKG11235.1 - 5e-06 25.6 0.6 0.00011 21.2 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG11235.1 - 1.4e-05 23.7 0.3 3.1e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EKG11235.1 - 0.00017 20.5 1.1 0.00039 19.3 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EKG11235.1 - 0.00019 21.0 0.1 0.0055 16.2 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EKG11235.1 - 0.0002 21.5 2.5 0.25 11.6 0.1 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.2 EKG11235.1 - 0.00048 19.3 0.1 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EKG11235.1 - 0.00075 18.6 0.1 0.0032 16.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EKG11235.1 - 0.001 18.1 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FMO-like PF00743.14 EKG11235.1 - 0.0017 16.6 0.1 0.081 11.0 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.18 EKG11235.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EKG11235.1 - 0.024 14.7 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FMN_dh PF01070.13 EKG11235.1 - 0.028 13.2 0.5 0.12 11.2 0.5 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase GIDA PF01134.17 EKG11235.1 - 0.033 13.0 1.6 0.048 12.5 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EKG11235.1 - 0.057 12.3 0.3 5.4 5.8 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EKG11235.1 - 0.064 13.0 0.2 0.27 10.9 0.0 2.2 2 0 0 2 2 1 0 FAD-NAD(P)-binding DJ-1_PfpI PF01965.19 EKG11235.1 - 0.12 11.8 0.0 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 DJ-1/PfpI family PmbA_TldD PF01523.11 EKG11235.1 - 0.12 11.5 0.2 0.46 9.7 0.2 1.8 2 0 0 2 2 2 0 Putative modulator of DNA gyrase 2-Hacid_dh_C PF02826.14 EKG11235.1 - 0.18 10.9 0.7 0.53 9.4 0.0 2.1 3 0 0 3 3 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EKG11235.1 - 0.2 10.9 0.9 0.41 9.9 0.1 1.8 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EKG11235.1 - 2 8.0 3.0 0.69 9.5 0.1 1.7 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EKG11237.1 - 3.2e-24 86.1 0.2 7.4e-23 81.6 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG11237.1 - 1.3e-17 63.2 0.0 8.5e-14 50.6 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EKG11237.1 - 1.6e-13 50.2 0.1 8e-09 34.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EKG11237.1 - 1.1e-10 41.7 0.0 5.9e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG11237.1 - 1.3e-08 35.0 0.3 0.0095 16.3 0.2 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG11237.1 - 1e-06 28.6 0.0 2.1e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EKG11237.1 - 3.6e-06 26.2 0.3 0.00011 21.4 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EKG11237.1 - 6.8e-06 25.3 0.3 0.0059 15.7 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EKG11237.1 - 1.6e-05 23.9 0.9 0.012 14.6 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein IlvN PF07991.7 EKG11237.1 - 3.9e-05 23.0 0.1 0.00031 20.1 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 EKG11237.1 - 0.00012 21.8 0.1 0.18 11.5 0.0 3.0 2 1 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EKG11237.1 - 0.00034 20.7 0.1 0.35 10.9 0.1 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EKG11237.1 - 0.00073 19.5 0.2 0.46 10.4 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain HI0933_like PF03486.9 EKG11237.1 - 0.0013 17.3 0.3 0.0096 14.4 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein 3HCDH_N PF02737.13 EKG11237.1 - 0.0013 18.3 1.1 1.6 8.3 0.5 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG11237.1 - 0.002 18.4 0.1 1.9 8.9 0.1 3.2 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.19 EKG11237.1 - 0.0042 16.0 0.9 0.092 11.5 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EKG11237.1 - 0.0059 15.5 0.8 0.53 9.0 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 EKG11237.1 - 0.008 15.1 0.4 0.3 9.9 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EKG11237.1 - 0.0097 15.0 0.2 2.6 7.0 0.0 3.4 4 0 0 4 4 4 1 Thi4 family NAD_binding_2 PF03446.10 EKG11237.1 - 0.019 14.8 0.1 6.1 6.6 0.0 2.4 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 EKG11237.1 - 0.077 12.8 0.6 9.2 6.0 0.1 2.4 2 0 0 2 2 2 0 ThiF family ApbA PF02558.11 EKG11237.1 - 0.094 12.1 1.1 1.9 7.8 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA ELFV_dehydrog PF00208.16 EKG11237.1 - 0.12 11.9 0.6 0.35 10.4 0.3 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_clus PF00172.13 EKG11238.1 - 1.6e-07 31.1 8.7 3.2e-07 30.1 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EKG11238.1 - 0.0054 15.6 0.8 0.01 14.7 0.5 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phage_CP76 PF06892.6 EKG11238.1 - 0.13 11.5 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) ADH_zinc_N PF00107.21 EKG11239.1 - 2.5e-17 62.6 0.5 4.3e-17 61.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG11239.1 - 1.5e-07 32.3 0.1 5.4e-07 30.5 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EKG11239.1 - 0.00088 19.6 0.4 0.00088 19.6 0.3 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EKG11239.1 - 0.0024 17.2 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EKG11239.1 - 0.0029 17.2 0.7 0.0042 16.7 0.5 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EKG11239.1 - 0.0032 16.6 0.1 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EKG11239.1 - 0.0035 16.2 0.9 0.0043 15.9 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain AdoHcyase_NAD PF00670.16 EKG11239.1 - 0.022 14.6 0.7 0.23 11.2 0.5 2.0 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 EKG11239.1 - 0.025 13.0 0.2 0.16 10.3 0.2 1.9 2 0 0 2 2 2 0 HI0933-like protein Gcd10p PF04189.8 EKG11239.1 - 0.03 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Gcd10p family DUF43 PF01861.11 EKG11239.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_26 PF13659.1 EKG11239.1 - 0.15 12.1 0.8 0.25 11.3 0.6 1.5 1 1 0 1 1 1 0 Methyltransferase domain AA_permease_2 PF13520.1 EKG11241.1 - 5.6e-59 199.7 53.9 6.7e-59 199.5 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG11241.1 - 1.3e-36 125.9 44.7 1.8e-36 125.5 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease MitMem_reg PF13012.1 EKG11242.1 - 2.1e-39 134.1 0.0 5.1e-39 132.9 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EKG11242.1 - 7.5e-28 96.5 0.0 1.5e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HAD_2 PF13419.1 EKG11244.1 - 2e-21 76.9 0.0 7.5e-10 39.2 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG11244.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like RFXA_RFXANK_bdg PF15289.1 EKG11244.1 - 0.11 12.6 0.4 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain Pkinase PF00069.20 EKG11245.1 - 3.2e-59 200.2 0.0 4.5e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG11245.1 - 4.1e-35 121.1 0.0 5.7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG11245.1 - 1.5e-11 43.8 0.0 6.3e-09 35.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EKG11245.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG11245.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.17 EKG11246.1 - 2.4e-35 121.9 0.0 3e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UCH PF00443.24 EKG11247.1 - 2.2e-22 79.4 0.0 3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Amidase PF01425.16 EKG11249.1 - 7.3e-61 206.3 0.0 1.4e-60 205.4 0.0 1.4 1 1 0 1 1 1 1 Amidase Aminotran_1_2 PF00155.16 EKG11250.1 - 2.7e-22 79.2 0.0 3e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II zinc-ribbons_6 PF07191.7 EKG11251.1 - 0.058 13.1 0.6 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbons CHORD PF04968.7 EKG11251.1 - 0.42 10.9 0.1 0.42 10.9 0.1 2.6 2 1 0 2 2 2 0 CHORD FAD_binding_2 PF00890.19 EKG11252.1 - 5e-16 58.5 0.0 6e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF1275 PF06912.6 EKG11253.1 - 2e-33 115.3 11.3 2.4e-33 115.1 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PEP_mutase PF13714.1 EKG11254.1 - 1.1e-45 155.7 0.1 1.3e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EKG11254.1 - 1.4e-18 66.4 0.1 1.9e-18 65.9 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family HTH_Tnp_Tc5 PF03221.11 EKG11255.1 - 0.0082 15.9 0.3 0.018 14.8 0.2 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain TPP_enzyme_N PF02776.13 EKG11257.1 - 0.0048 16.4 0.0 0.0061 16.0 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF382 PF04037.8 EKG11258.1 - 1.9e-61 205.5 1.0 4.7e-61 204.2 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EKG11258.1 - 1.9e-21 75.1 7.3 4e-21 74.1 5.1 1.6 1 0 0 1 1 1 1 PSP PUF PF00806.14 EKG11259.1 - 2.3e-56 184.2 9.8 5.3e-08 31.9 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF1736 PF08409.6 EKG11260.1 - 0.098 12.2 0.0 0.92 9.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1736) Glyco_hydro_61 PF03443.9 EKG11261.1 - 1.2e-78 263.8 1.1 2e-78 263.1 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF676 PF05057.9 EKG11263.1 - 0.00023 20.5 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EKG11263.1 - 0.00074 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 EKG11263.1 - 0.026 13.5 0.0 0.035 13.0 0.0 1.3 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.8 EKG11263.1 - 0.039 13.5 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF1057 PF06342.7 EKG11263.1 - 0.09 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF829 PF05705.9 EKG11263.1 - 0.13 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EKG11263.1 - 0.14 12.0 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Condensation PF00668.15 EKG11264.1 - 0.0012 17.7 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Condensation domain zf-RING_2 PF13639.1 EKG11265.1 - 5.1e-10 39.0 2.6 5.1e-10 39.0 1.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EKG11265.1 - 4.3e-07 29.9 6.9 1.3e-06 28.3 4.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKG11265.1 - 8.2e-06 25.7 9.1 1.7e-05 24.7 2.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG11265.1 - 3.5e-05 23.3 5.0 9e-05 22.0 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG11265.1 - 7.6e-05 22.3 0.9 7.6e-05 22.3 0.6 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EKG11265.1 - 0.00045 19.8 1.4 0.00045 19.8 1.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG11265.1 - 0.00047 19.7 2.6 0.00047 19.7 1.8 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EKG11265.1 - 0.0013 18.5 0.6 0.0013 18.5 0.4 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EKG11265.1 - 0.0033 17.2 2.3 0.0033 17.2 1.6 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING FYDLN_acid PF09538.5 EKG11265.1 - 0.0072 16.8 11.1 0.023 15.2 7.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) Prok-RING_4 PF14447.1 EKG11265.1 - 0.0077 15.7 0.3 0.0077 15.7 0.2 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Nop14 PF04147.7 EKG11265.1 - 0.011 13.7 7.5 0.012 13.5 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family FANCL_C PF11793.3 EKG11265.1 - 0.019 14.9 8.7 0.68 9.9 6.0 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.1 EKG11265.1 - 0.022 14.5 0.2 0.042 13.6 0.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 EKG11265.1 - 0.046 13.2 1.0 0.082 12.4 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2457 PF10446.4 EKG11265.1 - 1.2 7.8 25.5 0.61 8.7 16.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) EBV-NA3 PF05009.7 EKG11265.1 - 1.9 7.6 4.8 3.3 6.8 3.3 1.5 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 EKG11265.1 - 2 6.3 8.5 3 5.7 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 EKG11265.1 - 4.6 6.8 13.2 7.3 6.1 9.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 EKG11265.1 - 5 6.2 16.3 9.1 5.4 11.3 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1878 PF08963.5 EKG11266.1 - 0.03 14.5 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1878) UPF0061 PF02696.9 EKG11268.1 - 8.9e-75 251.8 0.0 1e-74 251.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3216 PF11505.3 EKG11268.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) PALP PF00291.20 EKG11270.1 - 2.1e-43 148.7 0.7 2.1e-43 148.7 0.5 2.2 3 0 0 3 3 3 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EKG11270.1 - 2e-25 89.4 0.3 4.1e-25 88.4 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EKG11270.1 - 9.7e-17 60.7 0.0 3e-16 59.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain TRI12 PF06609.8 EKG11270.1 - 6.1e-13 47.8 8.9 8.8e-13 47.3 6.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG11270.1 - 2.6e-12 46.1 32.6 4.7e-12 45.3 22.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M28 PF04389.12 EKG11270.1 - 0.12 12.0 0.4 0.27 10.9 0.3 1.5 1 0 0 1 1 1 0 Peptidase family M28 ER_lumen_recept PF00810.13 EKG11272.1 - 5.7e-55 185.8 9.1 8.3e-55 185.3 6.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EKG11272.1 - 0.11 12.1 7.2 7.2 6.2 0.0 3.9 4 0 0 4 4 4 0 PQ loop repeat ORC5_C PF14630.1 EKG11273.1 - 2.1e-79 266.8 0.0 3e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EKG11273.1 - 1.8e-12 47.6 0.5 5e-12 46.1 0.2 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG11273.1 - 0.002 18.3 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EKG11273.1 - 0.022 14.4 0.1 0.061 12.9 0.1 1.8 1 1 0 1 1 1 0 NACHT domain DUF1479 PF07350.7 EKG11274.1 - 5.6e-08 31.6 0.0 0.014 13.8 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.8 EKG11274.1 - 3.4e-05 23.9 0.2 0.00015 21.8 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EKG11274.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase FAD_binding_4 PF01565.18 EKG11276.1 - 3.6e-16 58.8 0.4 6.6e-16 58.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain DHHA1 PF02272.14 EKG11276.1 - 0.042 13.5 0.3 0.097 12.3 0.0 1.7 2 0 0 2 2 2 0 DHHA1 domain 2-Hacid_dh_C PF02826.14 EKG11277.1 - 3e-55 186.1 0.0 4e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG11277.1 - 7.2e-16 57.8 0.0 1e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EKG11277.1 - 6.4e-07 29.3 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EKG11277.1 - 0.0058 17.0 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AMP-binding PF00501.23 EKG11278.1 - 1.9e-33 115.4 0.0 6.7e-33 113.6 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EKG11278.1 - 5.4e-05 23.3 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG11278.1 - 0.074 14.0 0.1 0.21 12.5 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EKG11280.1 - 1.3e-23 83.3 16.3 6.3e-12 44.8 0.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily PEP_mutase PF13714.1 EKG11281.1 - 1.3e-46 158.7 0.4 1.5e-46 158.5 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EKG11281.1 - 1.1e-15 56.8 0.2 1.5e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EKG11281.1 - 0.0031 16.6 0.0 0.41 9.7 0.0 2.4 2 1 0 2 2 2 2 Ketopantoate hydroxymethyltransferase BsuBI_PstI_RE PF06616.6 EKG11281.1 - 0.015 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus DAHP_synth_1 PF00793.15 EKG11281.1 - 0.086 11.5 0.0 0.23 10.1 0.0 1.6 2 0 0 2 2 2 0 DAHP synthetase I family NUDIX PF00293.23 EKG11282.1 - 9.4e-16 57.6 0.1 1.9e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain FMN_dh PF01070.13 EKG11284.1 - 9.8e-109 363.4 0.0 1.3e-108 363.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EKG11284.1 - 3.3e-21 74.8 0.0 7.8e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EKG11284.1 - 9e-08 31.3 0.1 0.00017 20.5 0.1 2.3 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EKG11284.1 - 2.2e-07 30.1 0.1 3.5e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EKG11284.1 - 0.0079 15.4 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 Histidine biosynthesis protein ATP11 PF06644.6 EKG11284.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein NMO PF03060.10 EKG11284.1 - 0.04 13.0 1.2 0.05 12.7 0.2 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase DHO_dh PF01180.16 EKG11284.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.14 EKG11284.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF2196 PF09962.4 EKG11285.1 - 1.6e-21 75.7 4.0 2.5e-21 75.1 2.8 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) TPR_11 PF13414.1 EKG11286.1 - 0.00063 19.3 1.9 0.0059 16.2 0.3 2.4 2 0 0 2 2 2 1 TPR repeat TPR_14 PF13428.1 EKG11286.1 - 0.013 16.0 1.9 0.85 10.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKG11286.1 - 0.14 12.4 0.2 0.68 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKG11286.1 - 0.33 11.6 5.9 3.7 8.3 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyoxalase PF00903.20 EKG11287.1 - 7.4e-23 80.9 0.9 3.1e-17 62.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EKG11287.1 - 1.4e-15 57.2 1.2 1e-06 28.6 0.6 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EKG11287.1 - 3.2e-11 43.7 0.1 0.0002 21.9 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EKG11287.1 - 1.1e-05 25.4 0.7 0.0013 18.7 0.3 2.6 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EKG11287.1 - 1.3e-05 25.2 0.9 0.046 13.6 0.0 3.3 3 1 0 3 3 3 2 Glyoxalase-like domain zf-U1 PF06220.7 EKG11287.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 U1 zinc finger HIG_1_N PF04588.8 EKG11289.1 - 3.6e-08 33.0 1.0 6.9e-08 32.1 0.7 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Fasciclin PF02469.17 EKG11291.1 - 8.7e-19 67.7 0.1 3.4e-13 49.7 0.0 3.8 3 1 0 3 3 3 2 Fasciclin domain FAM165 PF14981.1 EKG11291.1 - 0.069 12.6 0.6 0.14 11.6 0.4 1.5 1 0 0 1 1 1 0 FAM165 family VTC PF09359.5 EKG11292.1 - 1.5e-94 316.1 0.2 2.2e-94 315.6 0.1 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EKG11292.1 - 8.3e-23 81.5 5.9 8.9e-21 74.8 4.1 3.2 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 EKG11292.1 - 8e-09 35.5 3.3 1.6e-08 34.6 2.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Lge1 PF11488.3 EKG11292.1 - 0.031 14.4 0.8 0.82 9.9 0.1 2.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 BLOC1_2 PF10046.4 EKG11292.1 - 0.08 13.0 5.5 0.81 9.8 0.1 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.8 EKG11292.1 - 0.23 11.5 4.6 0.26 11.3 1.0 2.2 2 0 0 2 2 2 0 DivIVA protein HATPase_c PF02518.21 EKG11293.1 - 2.1e-22 78.9 0.0 4.9e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG11293.1 - 7.6e-20 70.9 0.1 1.6e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EKG11293.1 - 4.2e-10 39.9 0.0 4.7e-07 30.1 0.0 3.3 3 0 0 3 3 3 2 PAS domain HisKA PF00512.20 EKG11293.1 - 8e-08 32.1 0.2 8e-08 32.1 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EKG11293.1 - 0.011 15.8 0.0 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 GAF domain GAF_2 PF13185.1 EKG11293.1 - 0.019 15.4 0.0 6.9 7.1 0.0 3.2 1 1 1 2 2 2 0 GAF domain Herpes_IE68 PF02479.11 EKG11293.1 - 0.089 11.9 0.6 0.26 10.4 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus immediate early protein Abp2 PF09441.5 EKG11294.1 - 1.7e-78 262.5 0.0 2.5e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Mito_carr PF00153.22 EKG11295.1 - 3e-54 180.6 1.3 4.7e-18 64.6 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EKG11295.1 - 0.008 15.9 0.2 0.019 14.7 0.1 1.6 1 0 0 1 1 1 1 UcrQ family ATP_synt_I PF03899.10 EKG11295.1 - 9.3 6.4 7.7 6.3 7.0 0.0 3.5 4 1 0 4 4 4 0 ATP synthase I chain RRM_1 PF00076.17 EKG11296.1 - 8.1e-07 28.5 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG11296.1 - 5e-06 26.2 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG11296.1 - 4.6e-05 23.3 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EKG11296.1 - 0.0021 18.2 0.0 0.14 12.4 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Citrate_synt PF00285.16 EKG11297.1 - 4.5e-103 344.7 0.0 5.4e-103 344.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 EKG11297.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 XH domain Eclosion PF04736.7 EKG11297.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 EKG11298.1 - 5.5e-32 109.3 4.4 3.1e-13 49.2 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 EKG11299.1 - 5e-100 335.1 13.3 5.9e-100 334.9 9.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11299.1 - 2.9e-28 98.6 28.0 7.7e-24 84.0 2.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_18A PF09771.4 EKG11299.1 - 0.079 12.9 1.0 1.5 8.8 0.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 188 PMT PF02366.13 EKG11300.1 - 8.2e-86 287.3 15.9 8.2e-86 287.3 11.0 2.4 2 1 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EKG11300.1 - 6.5e-39 133.4 0.5 9e-39 132.9 0.3 1.2 1 0 0 1 1 1 1 MIR domain Band_7 PF01145.20 EKG11302.1 - 1.3e-29 103.3 0.5 1.3e-29 103.3 0.4 3.3 4 1 0 4 4 4 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EKG11302.1 - 0.3 10.5 0.0 0.47 9.9 0.0 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family PAS_9 PF13426.1 EKG11304.1 - 2.5e-19 69.5 0.0 2.3e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EKG11304.1 - 1.3e-07 31.4 0.0 2.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EKG11304.1 - 0.0013 18.7 0.0 0.032 14.2 0.0 2.7 2 0 0 2 2 2 1 PAS fold Corona_nucleoca PF00937.13 EKG11304.1 - 0.09 11.7 6.7 2.1 7.2 0.9 2.5 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Glyco_tranf_2_3 PF13641.1 EKG11305.1 - 1.5e-34 119.8 0.0 2.7e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EKG11305.1 - 4.6e-13 49.2 0.6 4.6e-13 49.2 0.4 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EKG11305.1 - 4.9e-12 45.8 0.0 7.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EKG11305.1 - 4.7e-10 39.0 0.0 8.1e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EKG11305.1 - 1.1e-08 33.8 0.3 0.0058 14.9 0.0 3.5 2 1 2 4 4 4 3 Cellulose synthase Fungal_trans PF04082.13 EKG11307.1 - 7e-22 77.5 0.1 1.1e-21 76.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG11307.1 - 2.2e-08 33.8 10.4 2.2e-08 33.8 7.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arf PF00025.16 EKG11308.1 - 6.4e-80 266.4 0.2 7.3e-80 266.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKG11308.1 - 2.9e-14 52.6 0.0 3.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EKG11308.1 - 6.2e-13 48.4 0.0 6.7e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EKG11308.1 - 9.2e-13 47.6 1.6 1.1e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EKG11308.1 - 4.8e-11 42.2 0.0 5.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EKG11308.1 - 2.3e-08 34.5 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKG11308.1 - 3.7e-06 26.8 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG11308.1 - 0.007 15.8 0.1 0.057 12.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EKG11308.1 - 0.0085 15.1 0.3 0.015 14.3 0.2 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EKG11308.1 - 0.043 13.6 0.2 0.12 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain zf-U1 PF06220.7 EKG11309.1 - 3.8e-10 39.1 0.2 6.1e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 U1 zinc finger Tim54 PF11711.3 EKG11310.1 - 1.3e-17 63.4 0.6 1.5e-17 63.2 0.4 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Hira PF07569.6 EKG11311.1 - 2.2e-82 275.5 0.0 3.8e-82 274.7 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EKG11311.1 - 1.6e-42 141.9 17.5 7.8e-07 28.7 0.0 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat HIRA_B PF09453.5 EKG11311.1 - 3.6e-12 45.4 0.6 7.8e-12 44.4 0.4 1.6 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EKG11311.1 - 0.00018 21.0 1.0 16 5.3 0.0 4.6 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EKG11311.1 - 0.059 11.1 0.4 0.49 8.1 0.0 2.2 3 0 0 3 3 3 0 IKI3 family DUF866 PF05907.8 EKG11316.1 - 3.5e-52 176.1 0.1 3.9e-52 176.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.24 EKG11316.1 - 0.066 12.9 1.0 0.15 11.8 0.7 1.6 1 0 0 1 1 1 0 PHD-finger DUF3716 PF12511.3 EKG11316.1 - 1.6 8.4 5.5 3.2 7.4 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) Mito_fiss_reg PF05308.6 EKG11317.1 - 0.0045 16.3 2.1 0.0092 15.3 1.4 1.5 1 0 0 1 1 1 1 Mitochondrial fission regulator CAP_N PF01213.14 EKG11317.1 - 0.055 12.7 2.8 0.098 11.9 1.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PPR_3 PF13812.1 EKG11317.1 - 0.061 13.6 0.1 11 6.5 0.0 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 EKG11317.1 - 0.081 12.9 0.1 1 9.3 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family Mob1_phocein PF03637.12 EKG11318.1 - 1.3e-38 132.4 0.2 3.6e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 EKG11319.1 - 2e-33 115.4 2.2 2.1e-33 115.4 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Aa_trans PF01490.13 EKG11320.1 - 7.7e-28 97.1 36.3 9.1e-28 96.8 25.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PEMT PF04191.8 EKG11321.1 - 2.1e-32 111.3 2.1 4e-32 110.4 1.4 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase Tubulin PF00091.20 EKG11322.1 - 1.4e-70 237.4 0.0 2.5e-70 236.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKG11322.1 - 3.6e-49 165.9 0.1 6.4e-49 165.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EKG11322.1 - 8.7e-06 25.7 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EKG11322.1 - 0.0048 16.3 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Peptidase_M49 PF03571.10 EKG11323.1 - 1.2e-236 786.1 0.0 1.4e-236 785.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SLD3 PF08639.5 EKG11324.1 - 7.6e-79 265.6 4.5 9.9e-79 265.2 3.1 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 Glyco_hydro_1 PF00232.13 EKG11325.1 - 7.6e-26 90.3 1.8 3.1e-20 71.8 0.3 2.8 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 HET PF06985.6 EKG11326.1 - 1.3e-22 80.4 0.0 4.8e-22 78.6 0.0 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.9 EKG11329.1 - 6.9e-63 212.4 6.7 9.8e-63 211.9 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LsmAD PF06741.8 EKG11332.1 - 0.1 12.6 0.6 0.29 11.2 0.4 1.8 1 0 0 1 1 1 0 LsmAD domain Med15 PF09606.5 EKG11332.1 - 0.13 10.4 12.1 0.14 10.3 8.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2367 PF10164.4 EKG11333.1 - 0.025 14.4 1.3 0.031 14.1 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DUF756 PF05506.7 EKG11335.1 - 0.078 13.4 0.1 0.17 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF756) Sulfatase PF00884.18 EKG11340.1 - 6.2e-47 160.2 0.6 7.5e-47 159.9 0.4 1.1 1 0 0 1 1 1 1 Sulfatase Abhydro_lipase PF04083.11 EKG11340.1 - 0.077 12.3 0.0 0.88 8.9 0.0 2.4 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Retrotrans_gag PF03732.12 EKG11343.1 - 5.7e-15 55.1 1.7 1.5e-14 53.8 0.6 2.2 2 0 0 2 2 2 1 Retrotransposon gag protein WCCH PF03716.9 EKG11343.1 - 0.0064 15.9 1.7 0.039 13.4 0.1 3.0 3 0 0 3 3 3 1 WCCH motif DUF972 PF06156.8 EKG11343.1 - 0.018 15.3 0.1 0.18 12.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RVP_2 PF08284.6 EKG11343.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DivIC PF04977.10 EKG11343.1 - 0.15 11.5 1.0 0.47 9.9 0.7 1.8 1 0 0 1 1 1 0 Septum formation initiator EthD PF07110.6 EKG11344.1 - 1.1e-11 45.4 0.3 1.4e-11 45.1 0.2 1.1 1 0 0 1 1 1 1 EthD domain DUF1772 PF08592.6 EKG11345.1 - 2.7e-25 88.7 4.4 3.4e-25 88.3 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2976 PF11190.3 EKG11345.1 - 0.11 12.0 0.1 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) AMP-binding PF00501.23 EKG11346.1 - 1.1e-53 182.1 0.0 1.6e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme DUF4243 PF14027.1 EKG11347.1 - 3.1e-87 293.1 0.1 3.7e-87 292.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 EKG11348.1 - 3.6e-20 72.7 0.0 4.6e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG11348.1 - 6.5e-07 28.8 0.0 1.6e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EKG11348.1 - 0.0011 17.7 0.0 0.0018 17.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EKG11348.1 - 0.0014 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EKG11348.1 - 0.017 14.5 0.2 0.037 13.4 0.0 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG11348.1 - 0.025 13.5 0.0 0.046 12.6 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein GMC_oxred_N PF00732.14 EKG11349.1 - 3.4e-49 167.5 0.0 4.8e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG11349.1 - 1.9e-28 99.5 0.0 3.7e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EKG11349.1 - 3.4e-05 23.8 0.0 0.0015 18.4 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG11349.1 - 3.9e-05 22.7 0.0 6.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG11349.1 - 0.00013 21.8 0.0 0.00043 20.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG11349.1 - 0.001 18.0 0.0 0.014 14.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG11349.1 - 0.0086 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 EKG11349.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EKG11349.1 - 0.066 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 EKG11350.1 - 3.9e-25 88.6 5.2 1.3e-24 86.9 3.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG11350.1 - 1e-13 51.3 0.8 1.5e-13 50.8 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG11350.1 - 2.1e-09 37.1 0.0 2.4e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG11350.1 - 3.4e-05 23.9 0.6 5.6e-05 23.2 0.4 1.7 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EKG11350.1 - 5.8e-05 22.1 0.1 8.5e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EKG11350.1 - 0.0064 15.4 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EKG11350.1 - 0.021 13.7 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.8 EKG11350.1 - 0.042 13.0 0.2 0.075 12.2 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Ldh_1_N PF00056.18 EKG11350.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DFP PF04127.10 EKG11350.1 - 0.15 11.6 0.3 0.46 10.0 0.2 1.8 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Aldo_ket_red PF00248.16 EKG11351.1 - 6.2e-25 87.5 0.0 7.6e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EKG11352.1 - 8.1e-10 37.9 4.4 9.6e-10 37.6 3.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EKG11353.1 - 1.5e-06 27.2 23.7 1.5e-06 27.2 16.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EKG11354.1 - 1.1e-26 93.5 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Cu-oxidase_3 PF07732.10 EKG11355.1 - 3e-27 94.6 1.2 5.8e-24 84.0 0.4 2.1 1 1 1 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG11356.1 - 7.1e-40 135.7 0.7 3.2e-37 127.1 0.2 2.2 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG11356.1 - 3.1e-29 101.9 0.1 8.6e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 Multicopper oxidase GMC_oxred_N PF00732.14 EKG11357.1 - 5e-54 183.4 0.0 9.5e-54 182.5 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG11357.1 - 2e-33 115.6 0.0 3.8e-33 114.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EKG11357.1 - 3.2e-05 23.0 0.1 0.00012 21.1 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG11357.1 - 0.00021 21.2 0.0 0.0016 18.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG11357.1 - 0.0003 19.8 0.1 0.0021 17.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG11357.1 - 0.0004 20.5 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG11357.1 - 0.0012 18.7 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG11357.1 - 0.0036 15.8 0.1 0.012 14.1 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EKG11357.1 - 0.028 13.2 0.0 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EKG11357.1 - 0.061 13.1 0.6 0.19 11.4 0.0 2.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 EKG11357.1 - 0.085 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EKG11357.1 - 0.096 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain AflR PF08493.5 EKG11358.1 - 1.9e-29 102.5 9.4 3e-28 98.6 6.5 2.1 1 1 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EKG11358.1 - 8e-07 28.8 10.5 1.4e-06 28.0 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HDV_ag PF01517.13 EKG11358.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen L71 PF02448.10 EKG11359.1 - 0.057 13.2 0.2 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 L71 family p450 PF00067.17 EKG11360.1 - 5.8e-36 123.9 0.0 7.1e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF347 PF03988.7 EKG11360.1 - 0.082 12.8 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Herpes_glycop_D PF01537.12 EKG11362.1 - 0.091 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain MORN_2 PF07661.8 EKG11364.1 - 0.14 12.2 0.2 0.28 11.3 0.2 1.6 1 0 0 1 1 1 0 MORN repeat variant p450 PF00067.17 EKG11367.1 - 3.7e-52 177.3 0.0 4.7e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EKG11368.1 - 5.1e-35 121.0 0.0 6.5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG11368.1 - 8.4e-07 29.3 0.0 1.6e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG11368.1 - 4.1e-05 22.6 0.0 5.6e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Peptidase_M14 PF00246.19 EKG11369.1 - 7.7e-08 32.2 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EKG11369.1 - 0.022 13.8 0.2 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) CVNH PF08881.5 EKG11370.1 - 7.1e-22 77.6 0.1 1.2e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 CVNH domain SDA1 PF05285.7 EKG11370.1 - 0.00012 21.4 14.0 0.00015 21.1 9.7 1.1 1 0 0 1 1 1 1 SDA1 DUF4366 PF14283.1 EKG11370.1 - 0.017 14.5 4.8 0.03 13.7 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Serinc PF03348.10 EKG11370.1 - 0.17 10.5 0.3 0.23 10.1 0.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ycf1 PF05758.7 EKG11370.1 - 0.43 8.2 5.6 0.54 7.9 3.9 1.2 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 EKG11370.1 - 0.48 8.4 17.9 0.41 8.6 6.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Atrophin-1 PF03154.10 EKG11370.1 - 0.91 7.5 14.4 1.6 6.7 10.0 1.4 1 0 0 1 1 1 0 Atrophin-1 family FLO_LFY PF01698.11 EKG11370.1 - 6.1 5.5 16.3 10 4.8 11.3 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1446 PF07287.6 EKG11371.1 - 1.2e-135 451.6 1.2 1.7e-135 451.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1446) adh_short PF00106.20 EKG11371.1 - 3.4e-18 66.1 0.7 6.8e-18 65.1 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11371.1 - 7.4e-10 38.9 0.3 4e-09 36.6 0.2 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG11371.1 - 1.1e-08 34.9 0.6 1.8e-08 34.2 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG11371.1 - 3.8e-05 23.2 0.1 6.4e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG11371.1 - 0.00021 21.3 0.9 0.0013 18.7 0.2 2.6 3 1 0 3 3 3 1 NADH(P)-binding CoA_transf_3 PF02515.12 EKG11372.1 - 1.6e-35 122.1 0.0 8.1e-33 113.2 0.0 2.6 2 1 0 2 2 2 2 CoA-transferase family III SnoaL_3 PF13474.1 EKG11372.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain Fungal_trans PF04082.13 EKG11373.1 - 7.5e-22 77.4 0.0 1.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_16 PF00722.16 EKG11374.1 - 7.1e-08 31.9 0.3 1.2e-07 31.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3439 PF11921.3 EKG11375.1 - 0.44 10.2 11.8 1.2 8.9 8.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) adh_short PF00106.20 EKG11376.1 - 2.1e-12 47.2 0.0 4.4e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11376.1 - 0.00012 21.9 0.0 0.00092 19.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG11376.1 - 0.00015 21.3 0.0 0.00034 20.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG11376.1 - 0.00025 20.7 0.2 0.00048 19.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EKG11376.1 - 0.00032 20.7 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG11376.1 - 0.0057 16.3 0.0 0.02 14.5 0.0 1.8 1 1 0 1 1 1 1 KR domain RPA_interact_N PF14766.1 EKG11376.1 - 0.041 13.3 0.2 0.063 12.7 0.1 1.2 1 0 0 1 1 1 0 Replication protein A interacting N-terminal TPP_enzyme_N PF02776.13 EKG11377.1 - 3.4e-45 153.6 1.0 1.4e-44 151.5 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EKG11377.1 - 4e-27 94.6 0.1 1.4e-26 92.8 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EKG11377.1 - 1.9e-21 76.2 0.0 1.2e-20 73.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.11 EKG11377.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 2-Hacid_dh_C PF02826.14 EKG11382.1 - 1.2e-49 167.9 0.0 1.7e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG11382.1 - 5.8e-07 29.0 0.0 7.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EKG11382.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1871 PF08958.5 EKG11382.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1871) AgrD PF05931.6 EKG11382.1 - 0.15 11.6 0.2 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein DHDPS PF00701.17 EKG11383.1 - 2.1e-44 151.2 0.0 2.7e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family BNR_2 PF13088.1 EKG11384.1 - 3.3e-69 233.2 0.7 3.9e-69 232.9 0.5 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EKG11384.1 - 4e-09 34.9 1.2 0.098 12.5 0.0 4.3 3 0 0 3 3 3 3 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EKG11384.1 - 0.013 15.1 0.2 11 5.7 0.0 2.9 3 0 0 3 3 3 0 Mo-co oxidoreductase dimerisation domain PSII_BNR PF14870.1 EKG11384.1 - 0.017 14.0 0.1 0.053 12.5 0.0 1.8 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 Sugar_tr PF00083.19 EKG11385.1 - 2.7e-78 263.5 22.3 3.1e-78 263.3 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11385.1 - 4.1e-13 48.7 18.6 4.1e-13 48.7 12.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 EKG11386.1 - 0.00083 18.4 0.0 0.11 11.4 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II RecX PF02631.11 EKG11386.1 - 0.089 13.0 0.0 0.24 11.6 0.0 1.6 2 0 0 2 2 2 0 RecX family COesterase PF00135.23 EKG11389.1 - 7.6e-44 150.3 0.0 8.3e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG11389.1 - 6.7e-11 42.1 0.1 1.1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG11389.1 - 0.06 13.0 0.2 0.086 12.5 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family KH_1 PF00013.24 EKG11390.1 - 1.4e-84 277.6 26.8 6.9e-12 44.8 0.3 13.3 15 1 0 15 15 15 9 KH domain KH_3 PF13014.1 EKG11390.1 - 2.5e-60 199.3 27.0 1.3e-08 34.3 0.8 12.7 12 0 0 12 12 12 8 KH domain KH_2 PF07650.12 EKG11390.1 - 7.4e-13 47.8 26.5 0.0053 16.2 0.2 8.4 7 1 0 8 8 8 5 KH domain SLS PF14611.1 EKG11390.1 - 5.8e-10 38.9 6.2 0.14 11.5 0.0 7.3 6 3 3 9 9 9 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EKG11390.1 - 8.2e-05 22.1 5.2 14 5.3 0.0 5.2 4 0 0 4 4 4 2 KH domain KH_5 PF13184.1 EKG11390.1 - 0.014 15.1 7.8 13 5.7 0.1 5.7 6 0 0 6 6 6 0 NusA-like KH domain LeuA_dimer PF08502.5 EKG11390.1 - 0.015 15.0 0.3 0.35 10.6 0.0 3.2 3 0 0 3 3 3 0 LeuA allosteric (dimerisation) domain RPEL PF02755.10 EKG11390.1 - 0.057 12.7 1.9 1.5 8.2 0.1 3.0 3 0 0 3 3 3 0 RPEL repeat BMC PF00936.14 EKG11390.1 - 0.6 9.8 4.8 43 3.8 0.0 4.4 5 0 0 5 5 5 0 BMC domain GMC_oxred_C PF05199.8 EKG11391.1 - 1.2e-21 77.4 0.1 1.4e-21 77.2 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase HET PF06985.6 EKG11392.1 - 5.4e-19 68.7 0.1 1e-18 67.8 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EKG11392.1 - 4.9e-06 26.7 0.0 0.00014 22.0 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKG11392.1 - 0.0004 20.3 0.3 0.01 15.9 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EKG11392.1 - 0.0047 16.6 0.8 0.081 12.7 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeat Scytalone_dh PF02982.9 EKG11394.1 - 1.3e-62 210.1 2.2 2.1e-62 209.4 1.5 1.3 1 1 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EKG11394.1 - 0.0042 16.9 0.8 0.006 16.4 0.5 1.4 1 1 0 1 1 1 1 SnoaL-like domain adh_short PF00106.20 EKG11395.1 - 2.3e-32 112.2 1.2 3.6e-32 111.5 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11395.1 - 1.6e-30 106.6 0.3 1.9e-30 106.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG11395.1 - 1.1e-15 57.7 0.7 1.6e-15 57.2 0.5 1.1 1 0 0 1 1 1 1 KR domain B12-binding PF02310.14 EKG11395.1 - 0.011 15.5 0.3 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 B12 binding domain DUF1776 PF08643.5 EKG11395.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EKG11395.1 - 0.032 13.6 1.6 0.032 13.6 0.5 1.6 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EKG11395.1 - 0.063 12.3 0.2 0.62 9.1 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ketoacyl-synt PF00109.21 EKG11397.1 - 7.6e-73 245.1 0.0 2.5e-72 243.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG11397.1 - 4.9e-51 173.9 1.1 4.9e-51 173.9 0.7 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG11397.1 - 3e-34 117.4 0.6 9.5e-34 115.7 0.4 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EKG11397.1 - 2.1e-06 27.8 0.3 4.9e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EKG11397.1 - 6.1e-05 22.1 0.4 0.00022 20.3 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EKG11397.1 - 0.00048 19.8 1.1 0.0031 17.2 0.6 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family SNN_transmemb PF09049.5 EKG11401.1 - 0.062 13.0 1.3 0.12 12.1 0.9 1.4 1 0 0 1 1 1 0 Stannin transmembrane Arrestin_N PF00339.24 EKG11402.1 - 1.9e-05 24.4 0.0 9e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EKG11402.1 - 3.1e-05 23.2 0.0 4.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.7 EKG11402.1 - 0.00014 20.5 0.0 0.00028 19.5 0.0 1.4 1 0 0 1 1 1 1 Bul1 N terminus Vps26 PF03643.10 EKG11402.1 - 0.12 11.1 0.0 0.31 9.7 0.0 1.6 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 26 NmrA PF05368.8 EKG11403.1 - 0.02 14.1 0.0 0.026 13.7 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EKG11403.1 - 0.031 14.2 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding FeoB_N PF02421.13 EKG11403.1 - 0.04 13.1 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B ADH_zinc_N PF00107.21 EKG11403.1 - 0.043 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_4 PF07993.7 EKG11403.1 - 0.075 11.9 0.0 0.25 10.2 0.0 1.7 1 1 1 2 2 2 0 Male sterility protein Epimerase PF01370.16 EKG11403.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PepSY_2 PF13670.1 EKG11404.1 - 0.063 13.1 4.7 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain TCO89 PF10452.4 EKG11405.1 - 1.6e-07 30.6 1.0 0.00046 19.2 0.1 3.9 3 1 0 3 3 3 2 TORC1 subunit TCO89 DUF4611 PF15387.1 EKG11405.1 - 2.7 8.1 11.9 2.3 8.3 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF4243 PF14027.1 EKG11407.1 - 1.1e-84 284.6 0.1 1.6e-84 284.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) FAD_binding_3 PF01494.14 EKG11408.1 - 4.1e-15 55.6 1.9 5.3e-08 32.2 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EKG11408.1 - 0.015 15.2 0.4 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG11408.1 - 0.089 11.6 1.4 1.7 7.4 0.3 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG11408.1 - 0.11 12.3 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EKG11408.1 - 0.13 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_1 PF00667.15 EKG11409.1 - 1.1e-62 211.4 0.0 1.7e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EKG11409.1 - 7.7e-13 48.9 0.0 2.1e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EKG11409.1 - 1e-07 32.0 0.0 1.6e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EKG11409.1 - 0.0025 17.7 0.2 0.0069 16.3 0.2 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain RNase_PH_C PF03725.10 EKG11409.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Amidase PF01425.16 EKG11410.1 - 1.2e-78 264.9 0.0 1.4e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Amidase adh_short PF00106.20 EKG11411.1 - 1.9e-13 50.6 10.3 1.9e-13 50.6 7.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11411.1 - 2.6e-06 27.4 0.4 3.1e-06 27.1 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG11411.1 - 3.2e-06 26.9 8.7 4.9e-06 26.3 6.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EKG11411.1 - 0.039 13.7 2.2 0.075 12.8 1.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase dCMP_cyt_deam_1 PF00383.17 EKG11412.1 - 3.1e-09 36.4 0.1 6.9e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Fungal_trans PF04082.13 EKG11412.1 - 0.0023 16.8 1.2 0.0023 16.8 0.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Bd3614-deam PF14439.1 EKG11412.1 - 0.011 15.6 0.6 0.24 11.2 0.2 2.7 2 0 0 2 2 2 0 Bd3614-like deaminase UDPGT PF00201.13 EKG11414.1 - 1e-09 37.5 0.0 3.4e-08 32.4 0.0 2.0 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EKG11414.1 - 2.7e-06 27.1 0.2 5.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.1 EKG11414.1 - 0.076 12.1 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 1 DUF2306 PF10067.4 EKG11415.1 - 5.8e-09 36.0 9.1 5.8e-09 36.0 6.3 2.4 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) PrgI PF12666.2 EKG11415.1 - 0.0063 16.6 1.6 0.0063 16.6 1.1 3.1 3 1 1 4 4 4 1 PrgI family protein Phage_holin_6 PF10746.4 EKG11415.1 - 0.57 9.9 2.7 4 7.2 0.1 2.4 2 0 0 2 2 2 0 Phage holin family 6 Fungal_trans PF04082.13 EKG11416.1 - 2.1e-18 66.1 1.3 3e-18 65.6 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl_transf_1 PF00698.16 EKG11417.1 - 4.6e-37 128.0 0.3 7.5e-37 127.3 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG11417.1 - 3.3e-33 114.0 0.0 7.5e-33 112.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EKG11417.1 - 2.1e-08 33.9 0.5 4.7e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Abhydrolase_5 PF12695.2 EKG11417.1 - 0.0074 16.0 1.9 0.013 15.2 0.1 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 EKG11419.1 - 1.1e-69 234.7 0.1 1.9e-68 230.6 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG11419.1 - 3.6e-52 177.6 0.1 5.9e-52 176.9 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG11419.1 - 2.1e-39 134.0 0.0 4.6e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EKG11419.1 - 6.5e-33 114.1 0.0 1.2e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 EKG11419.1 - 3.5e-23 81.7 0.0 6.5e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EKG11419.1 - 2.4e-14 53.5 0.0 5.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG11419.1 - 8.2e-10 38.4 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EKG11419.1 - 1e-07 32.0 0.2 8e-06 25.8 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.7 EKG11419.1 - 6.6e-07 29.7 0.0 2.1e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG11419.1 - 9.9e-07 28.6 0.0 2.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG11419.1 - 3e-05 24.3 0.0 0.00016 21.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.5 EKG11419.1 - 0.0001 22.0 0.1 0.00044 19.9 0.0 2.2 2 0 0 2 2 2 1 KR domain RrnaAD PF00398.15 EKG11419.1 - 0.00015 20.9 0.0 0.00025 20.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Epimerase PF01370.16 EKG11419.1 - 0.00039 19.9 0.0 0.0036 16.7 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EKG11419.1 - 0.00052 20.5 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG11419.1 - 0.0025 17.8 0.1 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NodS PF05401.6 EKG11419.1 - 0.0095 15.3 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Polysacc_synt_2 PF02719.10 EKG11419.1 - 0.016 14.1 0.0 2.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein YflT PF11181.3 EKG11419.1 - 0.15 12.2 0.0 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Heat induced stress protein YflT Transferase PF02458.10 EKG11420.1 - 3.6e-19 68.5 0.0 8.8e-19 67.2 0.0 1.5 2 0 0 2 2 2 1 Transferase family FAD_binding_3 PF01494.14 EKG11421.1 - 1.1e-21 77.3 0.1 7.2e-21 74.6 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG11421.1 - 3.7e-08 32.6 0.1 2.2e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG11421.1 - 5e-05 23.2 0.4 0.00014 21.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG11421.1 - 0.00043 20.0 0.2 0.0023 17.7 0.2 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG11421.1 - 0.007 16.4 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG11421.1 - 0.0088 16.4 2.1 0.02 15.3 1.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EKG11421.1 - 0.011 14.8 0.1 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EKG11421.1 - 0.027 13.4 0.2 4.7 6.0 0.0 2.6 2 1 1 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EKG11421.1 - 0.032 14.1 0.5 0.056 13.3 0.4 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG11421.1 - 0.049 12.7 0.1 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EKG11421.1 - 0.067 12.0 0.0 5.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase DUF3072 PF11272.3 EKG11421.1 - 1.1 8.9 2.9 1.2 8.8 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) DUF4440 PF14534.1 EKG11422.1 - 0.096 12.9 0.1 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) ADH_N PF08240.7 EKG11423.1 - 1e-10 41.3 0.1 5.5e-10 38.9 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG11423.1 - 8.1e-07 28.6 0.1 1.3e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EKG11424.1 - 2.6e-21 75.5 1.0 1.5e-20 73.0 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase KR PF08659.5 EKG11424.1 - 8.7e-20 71.1 1.8 1.4e-19 70.4 0.4 1.9 2 0 0 2 2 2 1 KR domain ADH_zinc_N_2 PF13602.1 EKG11424.1 - 8.4e-16 59.0 0.0 3.4e-15 57.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.20 EKG11424.1 - 2.2e-14 53.7 4.6 4.7e-14 52.6 0.5 2.6 2 1 0 2 2 2 1 short chain dehydrogenase ADH_N PF08240.7 EKG11424.1 - 0.00037 20.2 0.0 0.00096 18.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EKG11424.1 - 0.017 14.5 0.3 0.28 10.5 0.1 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PALP PF00291.20 EKG11424.1 - 0.032 13.4 0.4 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme PS-DH PF14765.1 EKG11425.1 - 9.9e-54 182.4 0.0 1.6e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EKG11425.1 - 1.1e-53 182.6 0.0 1.5e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG11425.1 - 9.7e-37 125.4 2.5 1e-36 125.3 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EKG11425.1 - 4.2e-05 23.1 0.9 6e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ketoacyl-synt PF00109.21 EKG11426.1 - 1.8e-46 158.6 0.0 2.2e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EKG11426.1 - 0.038 13.6 0.9 0.059 13.0 0.1 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_6 PF12697.2 EKG11427.1 - 5.3e-16 59.1 0.0 6.9e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG11427.1 - 2.6e-13 49.9 0.0 4.1e-13 49.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EKG11427.1 - 1.1e-06 27.4 0.0 6.5e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EKG11427.1 - 2.7e-05 23.5 0.0 0.08 12.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EKG11427.1 - 0.0001 21.8 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EKG11427.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 EKG11427.1 - 0.015 13.8 0.0 0.021 13.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.3 EKG11427.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase DLH PF01738.13 EKG11427.1 - 0.17 11.1 0.0 0.72 9.0 0.0 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family Epimerase PF01370.16 EKG11429.1 - 6.6e-17 61.7 0.0 1.2e-16 60.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG11429.1 - 7e-10 38.0 0.0 9.6e-10 37.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG11429.1 - 9.5e-09 34.5 0.0 0.00074 18.5 0.0 2.0 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EKG11429.1 - 1e-08 35.4 0.6 2.2e-08 34.3 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EKG11429.1 - 1.1e-08 35.2 0.5 1.7e-08 34.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG11429.1 - 5.4e-05 22.9 0.1 0.0001 21.9 0.1 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EKG11429.1 - 0.0012 18.1 0.0 0.022 14.0 0.0 2.4 3 0 0 3 3 3 1 NmrA-like family Polysacc_synt_2 PF02719.10 EKG11429.1 - 0.02 13.8 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TTL PF03133.10 EKG11431.1 - 1.6e-27 96.1 0.0 1.1e-25 90.1 0.0 2.2 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Lactamase_B PF00753.22 EKG11432.1 - 1e-15 57.9 0.9 1.6e-15 57.3 0.6 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG11432.1 - 0.0013 18.2 0.2 0.0018 17.8 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.11 EKG11433.1 - 5.1e-37 127.3 26.5 5.8e-37 127.2 18.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CMD PF02627.15 EKG11434.1 - 4.9e-17 61.5 0.0 3.2e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Lactamase_B PF00753.22 EKG11434.1 - 5.8e-09 35.8 2.3 4.8e-08 32.8 1.6 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG11434.1 - 0.00036 20.1 0.4 0.00065 19.3 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain IFRD_C PF04836.7 EKG11434.1 - 0.057 13.6 0.3 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Interferon-related protein conserved region CMD PF02627.15 EKG11435.1 - 1.2e-19 69.8 0.1 2.3e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Fungal_trans PF04082.13 EKG11436.1 - 8.9e-11 41.1 0.6 9.2e-10 37.8 0.1 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain NAD_binding_2 PF03446.10 EKG11437.1 - 2.2e-31 108.9 0.1 3.5e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EKG11437.1 - 4.4e-23 81.6 0.0 7.6e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EKG11437.1 - 8.4e-08 31.3 0.0 1.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Lactamase_B PF00753.22 EKG11437.1 - 2.2e-07 30.7 0.6 4.4e-07 29.7 0.4 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG11437.1 - 6.1e-05 22.6 0.0 0.00017 21.1 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain F420_oxidored PF03807.12 EKG11437.1 - 6.3e-05 23.3 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EKG11437.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ADH_zinc_N PF00107.21 EKG11438.1 - 7.7e-17 61.0 0.3 7.7e-17 61.0 0.2 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG11438.1 - 1.8e-15 56.5 0.0 4.9e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EKG11440.1 - 1.8e-17 63.1 10.6 2.4e-17 62.6 7.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG11440.1 - 0.012 14.1 5.2 0.016 13.8 1.9 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter Form-deh_trans PF09163.6 EKG11440.1 - 0.037 13.5 0.5 0.11 12.0 0.3 1.8 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane Fungal_trans PF04082.13 EKG11441.1 - 8.2e-09 34.7 0.0 9.8e-09 34.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF92 PF01940.11 EKG11441.1 - 0.099 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF1707 PF08044.6 EKG11441.1 - 0.11 12.3 0.3 0.26 11.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) UCH PF00443.24 EKG11442.1 - 2.1e-54 184.4 0.0 2.9e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG11442.1 - 3.7e-22 79.1 0.0 6.4e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EKG11442.1 - 0.0068 16.7 0.0 0.047 14.0 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain VHS PF00790.14 EKG11443.1 - 1.5e-41 141.3 0.1 1.5e-41 141.3 0.1 1.9 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EKG11443.1 - 2.3e-17 62.6 3.1 4.2e-17 61.8 2.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EKG11443.1 - 0.00013 21.2 9.9 0.044 13.3 0.4 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EKG11443.1 - 0.0037 17.1 1.5 0.0077 16.1 1.1 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.16 EKG11443.1 - 0.0065 16.3 2.0 0.014 15.2 1.4 1.5 1 0 0 1 1 1 1 IBR domain GAT PF03127.9 EKG11443.1 - 0.011 15.6 0.1 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 GAT domain Ribosomal_S30AE PF02482.14 EKG11443.1 - 0.054 13.9 0.1 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein Gly_transf_sug PF04488.10 EKG11445.1 - 9.1e-08 32.4 0.0 1.9e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EKG11445.1 - 0.024 13.1 0.0 0.033 12.6 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Abhydrolase_3 PF07859.8 EKG11446.1 - 0.095 12.2 0.2 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold CD99L2 PF12301.3 EKG11449.1 - 0.0016 18.1 1.2 0.0016 18.1 0.8 1.8 1 1 0 1 1 1 1 CD99 antigen like protein 2 TMEM154 PF15102.1 EKG11449.1 - 0.058 13.1 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.1 EKG11449.1 - 0.12 11.8 0.3 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Shisa PF13908.1 EKG11449.1 - 0.19 11.8 0.3 0.31 11.1 0.2 1.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF912 PF06024.7 EKG11449.1 - 0.22 11.5 0.6 0.49 10.4 0.0 1.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NICE-3 PF07406.6 EKG11449.1 - 0.39 10.2 1.4 0.53 9.7 1.0 1.2 1 0 0 1 1 1 0 NICE-3 protein DUF1180 PF06679.7 EKG11449.1 - 0.42 10.4 6.1 0.12 12.2 1.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) TrbL PF04610.9 EKG11449.1 - 1.8 8.2 6.6 2.6 7.6 4.6 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF1469 PF07332.6 EKG11449.1 - 1.9 8.2 5.9 4.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Dak2 PF02734.12 EKG11450.1 - 6.1 6.4 13.4 0.019 14.6 0.5 3.0 2 1 0 2 2 2 0 DAK2 domain MinC_C PF03775.11 EKG11451.1 - 0.063 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain DUF4334 PF14232.1 EKG11452.1 - 5.1e-13 48.4 0.2 9.5e-13 47.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) GXWXG PF14231.1 EKG11452.1 - 8.7e-12 44.5 0.3 1.9e-11 43.4 0.2 1.6 1 1 0 1 1 1 1 GXWXG protein Pectate_lyase PF03211.8 EKG11454.1 - 4.7e-63 212.4 2.9 6.1e-63 212.0 2.0 1.1 1 0 0 1 1 1 1 Pectate lyase YSIRK_signal PF04650.12 EKG11454.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 YSIRK type signal peptide Alpha_L_fucos PF01120.12 EKG11455.1 - 3e-88 296.0 3.6 4.1e-88 295.5 2.5 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 EKG11455.1 - 0.062 13.3 0.1 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Rox3 PF08633.5 EKG11457.1 - 0.7 10.1 10.3 0.043 14.1 3.3 1.7 2 0 0 2 2 2 0 Rox3 mediator complex subunit p450 PF00067.17 EKG11458.1 - 6.6e-53 179.8 0.0 9.3e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EKG11459.1 - 2.7e-22 78.7 0.3 4e-22 78.1 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG11459.1 - 9.5e-08 32.9 0.2 3e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Mito_carr PF00153.22 EKG11460.1 - 5.8e-57 189.4 2.5 4.4e-20 71.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3611 PF12263.3 EKG11460.1 - 0.042 13.2 0.0 0.096 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) NinG PF05766.7 EKG11463.1 - 0.068 12.9 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Reductase_C PF14759.1 EKG11463.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Reductase C-terminal zf-HC2 PF13490.1 EKG11463.1 - 0.094 12.6 2.2 0.21 11.5 0.3 2.2 2 0 0 2 2 2 0 Putative zinc-finger NAD_binding_10 PF13460.1 EKG11464.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF3237 PF11578.3 EKG11465.1 - 1.9e-31 108.4 0.0 2.5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) NACHT PF05729.7 EKG11466.1 - 7.4e-08 32.2 1.3 6.4e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 EKG11466.1 - 0.00024 21.8 0.1 0.012 16.3 0.1 3.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG11466.1 - 0.0017 18.3 0.3 0.0017 18.3 0.2 3.3 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EKG11466.1 - 0.002 18.2 0.2 0.048 13.8 0.0 2.9 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG11466.1 - 0.0033 17.1 0.0 0.0081 15.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EKG11466.1 - 0.0091 15.4 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 EKG11466.1 - 0.02 14.1 0.2 6.9 5.8 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_23 PF13476.1 EKG11466.1 - 0.03 14.6 5.2 76 3.5 0.0 4.8 4 1 0 4 4 4 0 AAA domain AAA_18 PF13238.1 EKG11466.1 - 0.03 14.6 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EKG11466.1 - 0.03 14.5 0.0 0.77 9.9 0.0 3.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EKG11466.1 - 0.034 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 EKG11466.1 - 0.17 11.4 1.7 1.3 8.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain Glyco_hydro_61 PF03443.9 EKG11468.1 - 2.2e-57 194.3 0.0 2.6e-57 194.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Rifin_STEVOR PF02009.11 EKG11469.1 - 7.3 6.1 6.9 9.1 5.8 4.8 1.1 1 0 0 1 1 1 0 Rifin/stevor family zf-Nse PF11789.3 EKG11470.1 - 5.5e-21 73.8 0.0 9.7e-21 73.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EKG11470.1 - 0.00063 19.4 0.0 0.0015 18.1 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EKG11470.1 - 0.0023 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-MIZ PF02891.15 EKG11470.1 - 0.027 13.9 0.2 0.062 12.8 0.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Myb_DNA-bind_2 PF08914.6 EKG11472.1 - 2.3e-17 62.5 0.0 1.4e-16 60.0 0.0 2.4 3 0 0 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.3 EKG11472.1 - 2.3e-14 53.0 0.0 6.1e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.5 EKG11472.1 - 0.00021 21.7 0.3 0.058 13.9 0.0 3.0 2 1 0 2 2 2 1 Rap1, DNA-binding zf-DHHC PF01529.15 EKG11473.1 - 2.3e-37 128.0 0.1 3.7e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Proteasome PF00227.21 EKG11474.1 - 1.8e-43 148.0 0.1 2.4e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit FF PF01846.14 EKG11475.1 - 1.7e-12 47.0 8.3 2.1e-10 40.3 0.6 3.6 3 0 0 3 3 3 2 FF domain WW PF00397.21 EKG11475.1 - 1.5e-08 34.3 4.2 1.5e-08 34.3 2.9 3.0 3 0 0 3 3 3 1 WW domain TTSSLRR PF12468.3 EKG11475.1 - 1.6 8.3 7.0 5.3 6.6 4.8 1.9 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein GBP_C PF02841.9 EKG11475.1 - 8.8 5.4 17.4 0.33 10.0 7.1 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain FA_desaturase PF00487.19 EKG11476.1 - 0.0042 16.5 2.9 0.0042 16.5 2.0 2.1 1 1 1 2 2 2 1 Fatty acid desaturase PrgI PF12666.2 EKG11476.1 - 2.9 8.0 7.7 17 5.6 0.1 2.3 2 0 0 2 2 2 0 PrgI family protein DUF4407 PF14362.1 EKG11477.1 - 0.19 10.6 8.1 0.31 9.9 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.10 EKG11477.1 - 0.36 9.4 5.3 0.43 9.1 3.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EKG11477.1 - 1.1 7.2 8.1 1.4 6.8 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein vMSA PF00695.14 EKG11477.1 - 3.5 6.7 7.1 4.8 6.2 5.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Neur_chan_memb PF02932.11 EKG11477.1 - 7.9 6.2 7.1 11 5.8 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pox_MCEL PF03291.11 EKG11478.1 - 3.5e-67 226.6 0.0 2.5e-47 161.3 0.0 2.8 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EKG11478.1 - 6.2e-09 36.2 0.0 1.9e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG11478.1 - 8.9e-09 35.2 0.0 1.8e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG11478.1 - 1.5e-07 31.9 0.0 3.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG11478.1 - 2.2e-06 28.0 0.0 0.018 15.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EKG11478.1 - 1.4e-05 25.4 0.0 3.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG11478.1 - 5.2e-05 22.8 0.0 0.00019 21.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EKG11478.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF2058 PF09831.4 EKG11478.1 - 0.29 10.9 1.6 0.52 10.1 1.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) RPN7 PF10602.4 EKG11479.1 - 1.5e-56 190.6 0.8 2.4e-56 189.9 0.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EKG11479.1 - 7.8e-15 55.0 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EKG11479.1 - 0.063 13.1 0.0 0.27 11.1 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EKG11480.1 - 3.4e-38 131.5 0.0 4.6e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RCC1 PF00415.13 EKG11482.1 - 2.2e-23 82.2 0.0 6e-08 32.7 0.0 6.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EKG11482.1 - 4.8e-10 39.4 0.0 7.6e-06 25.8 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 EKG11482.1 - 6.9e-10 38.2 6.1 2e-08 33.5 0.3 3.4 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EKG11482.1 - 1.5e-08 34.8 0.4 9.1e-07 29.2 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG11482.1 - 1.5e-05 25.2 0.0 0.00042 20.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKG11482.1 - 4.5e-05 23.2 0.1 0.7 10.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EKG11482.1 - 0.0054 16.9 0.4 4.8 7.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) DUF1160 PF06648.6 EKG11482.1 - 0.24 11.1 0.1 0.51 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) Sugar_tr PF00083.19 EKG11483.1 - 3e-31 108.5 25.2 4.1e-28 98.1 17.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11483.1 - 4.7e-16 58.4 55.8 1.4e-14 53.5 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily COesterase PF00135.23 EKG11484.1 - 7.5e-14 51.3 0.1 1.6e-08 33.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family PEX11 PF05648.9 EKG11485.1 - 1.2e-70 237.2 0.7 1.4e-70 237.0 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Cyt-b5 PF00173.23 EKG11486.1 - 8.1e-24 83.2 0.1 1e-23 82.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PHY PF00360.15 EKG11487.1 - 4.9e-30 104.0 0.0 1.2e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EKG11487.1 - 4e-17 61.9 0.3 9.7e-17 60.6 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG11487.1 - 8.1e-16 58.0 0.0 3.3e-15 56.0 0.0 2.2 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EKG11487.1 - 2e-15 57.2 0.0 6.2e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 EKG11487.1 - 5.4e-13 48.7 0.5 1.7e-12 47.1 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EKG11487.1 - 8.2e-10 39.1 0.0 2.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EKG11487.1 - 0.0035 17.6 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 PAS domain PH_8 PF15409.1 EKG11487.1 - 0.082 12.9 0.0 0.86 9.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Flavoprotein PF02441.14 EKG11488.1 - 7.5e-17 61.2 0.1 1.4e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein Dimer_Tnp_hAT PF05699.9 EKG11488.1 - 0.49 10.0 4.4 7.3 6.2 0.1 4.0 4 1 1 5 5 5 0 hAT family C-terminal dimerisation region MFS_1 PF07690.11 EKG11490.1 - 2.1e-33 115.5 30.0 2.1e-33 115.5 20.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Med13_C PF06333.7 EKG11491.1 - 9e-76 255.0 0.0 3.8e-65 220.1 0.0 2.9 3 0 0 3 3 3 2 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EKG11491.1 - 2.8e-12 46.0 0.0 2.8e-12 46.0 0.0 2.8 2 1 0 2 2 2 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 EKG11492.1 - 2.1e-11 43.1 0.8 5.8e-11 41.7 0.6 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EKG11492.1 - 0.015 15.1 0.1 0.89 9.5 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat E1-E2_ATPase PF00122.15 EKG11493.1 - 1.4e-67 227.0 3.1 1e-66 224.2 0.0 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EKG11493.1 - 9.6e-24 84.9 0.0 2.9e-23 83.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG11493.1 - 2.1e-12 47.5 0.0 4.6e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKG11493.1 - 2.2e-10 39.8 0.0 4.8e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EKG11493.1 - 0.0011 18.5 0.1 0.0042 16.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG11493.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit GNVR PF13807.1 EKG11493.1 - 0.082 12.6 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase 3Beta_HSD PF01073.14 EKG11494.1 - 2e-19 69.3 0.0 3.6e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKG11494.1 - 2.8e-18 66.2 0.1 4.1e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG11494.1 - 7.3e-12 45.6 1.1 1.8e-11 44.3 0.8 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EKG11494.1 - 1.7e-10 40.2 0.0 5.9e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EKG11494.1 - 1.9e-08 34.4 0.2 3.8e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EKG11494.1 - 2.4e-07 30.2 0.3 1.6e-06 27.5 0.2 2.0 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EKG11494.1 - 3.7e-06 26.0 0.1 5.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EKG11494.1 - 1.8e-05 24.4 0.1 3.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EKG11494.1 - 0.051 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pkinase PF00069.20 EKG11496.1 - 8.4e-28 97.2 0.0 1.1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG11496.1 - 1.5e-11 43.8 0.0 6.2e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HET PF06985.6 EKG11498.1 - 5.5e-24 84.9 0.0 1.2e-23 83.8 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EKG11498.1 - 2.4e-18 66.2 0.0 4e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG11498.1 - 3.1e-07 29.7 0.0 1.4e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Cation_efflux PF01545.16 EKG11499.1 - 2.2e-32 112.2 1.1 2.8e-32 111.9 0.8 1.1 1 0 0 1 1 1 1 Cation efflux family Patched PF02460.13 EKG11500.1 - 1.2e-75 255.0 7.4 2.8e-49 167.7 0.0 2.1 2 0 0 2 2 2 2 Patched family DUF2433 PF10360.4 EKG11500.1 - 1e-49 168.2 0.0 1.7e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Sterol-sensing PF12349.3 EKG11500.1 - 1.6e-49 167.3 6.7 1.6e-49 167.3 4.6 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EKG11500.1 - 9.6e-05 21.2 13.7 9.6e-05 21.2 9.5 3.6 3 1 0 3 3 3 1 MMPL family Metallophos_2 PF12850.2 EKG11500.1 - 0.0043 16.9 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4366 PF14283.1 EKG11500.1 - 0.17 11.3 0.1 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) HEAT_2 PF13646.1 EKG11501.1 - 1.2e-19 70.3 11.3 0.00017 21.8 0.9 8.5 6 2 2 9 9 9 4 HEAT repeats HEAT PF02985.17 EKG11501.1 - 3.7e-19 67.0 6.9 9.5e-05 22.1 0.0 10.1 10 0 0 10 10 8 2 HEAT repeat HEAT_EZ PF13513.1 EKG11501.1 - 2.3e-13 50.2 22.2 0.00041 20.7 1.1 11.6 10 4 2 12 12 11 4 HEAT-like repeat IBN_N PF03810.14 EKG11501.1 - 2.3e-13 49.8 1.2 1e-12 47.7 0.5 2.6 2 0 0 2 2 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EKG11501.1 - 8.5e-11 40.8 0.1 0.01 14.2 0.0 5.0 4 2 1 5 5 5 3 Adaptin N terminal region Cnd1 PF12717.2 EKG11501.1 - 3.8e-08 33.3 4.0 0.016 15.0 0.1 4.9 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 EKG11501.1 - 1e-07 31.8 0.0 0.29 10.7 0.0 5.4 4 2 1 5 5 5 2 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 EKG11501.1 - 3.3e-07 30.5 0.0 0.9 9.9 0.0 6.9 7 2 1 8 8 8 1 Vacuolar 14 Fab1-binding region UME PF08064.8 EKG11501.1 - 0.00029 20.7 0.1 0.13 12.1 0.0 4.5 3 1 0 4 4 4 1 UME (NUC010) domain CLASP_N PF12348.3 EKG11501.1 - 0.00031 20.1 0.2 0.2 11.0 0.0 4.5 6 0 0 6 6 6 1 CLASP N terminal MMS19_C PF12460.3 EKG11501.1 - 0.0022 16.8 8.2 0.029 13.0 0.0 5.1 3 2 0 5 5 5 1 RNAPII transcription regulator C-terminal ParcG PF10274.4 EKG11501.1 - 0.0091 15.9 1.3 0.31 10.9 0.0 3.3 3 0 0 3 3 3 1 Parkin co-regulated protein MSP1_C PF07462.6 EKG11501.1 - 0.012 14.0 1.1 0.021 13.2 0.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Arm PF00514.18 EKG11501.1 - 0.039 13.7 10.4 10 6.1 0.0 7.5 9 0 0 9 9 9 0 Armadillo/beta-catenin-like repeat DUF4042 PF13251.1 EKG11501.1 - 0.22 10.9 7.5 4.5 6.7 0.0 5.1 5 1 0 5 5 5 0 Domain of unknown function (DUF4042) DUF3650 PF12368.3 EKG11502.1 - 0.22 11.0 1.3 0.33 10.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF1793 PF08760.6 EKG11503.1 - 1.5e-64 216.9 0.6 3e-64 216.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) RNase_T PF00929.19 EKG11504.1 - 0.00074 19.8 0.0 0.0087 16.3 0.0 2.2 1 1 0 1 1 1 1 Exonuclease CDC45 PF02724.9 EKG11505.1 - 0.22 9.5 3.2 0.25 9.3 2.2 1.0 1 0 0 1 1 1 0 CDC45-like protein GTP_EFTU PF00009.22 EKG11506.1 - 2.5e-51 173.8 0.3 4.6e-51 172.9 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EKG11506.1 - 2.2e-21 75.7 5.9 4.2e-21 74.8 4.1 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EKG11506.1 - 3.7e-09 36.5 0.0 9e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EKG11506.1 - 7.1e-08 32.5 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 EKG11506.1 - 5.2e-06 26.9 0.1 0.00024 21.5 0.1 2.6 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EKG11506.1 - 0.00014 21.3 0.2 0.0016 17.8 0.0 2.3 2 0 0 2 2 2 1 Ras family GTP_EFTU_D2 PF03144.20 EKG11506.1 - 0.00034 20.6 0.0 0.00093 19.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.13 EKG11506.1 - 0.0026 17.0 0.1 0.047 12.9 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EKG11506.1 - 0.0027 16.9 0.0 1.6 7.9 0.0 2.4 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EKG11506.1 - 0.005 16.0 0.0 0.01 14.9 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Septin PF00735.13 EKG11506.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Septin PNP_UDP_1 PF01048.15 EKG11507.1 - 1.1e-06 27.8 0.3 7.3e-06 25.1 0.2 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ubie_methyltran PF01209.13 EKG11508.1 - 6e-73 244.8 0.0 7.2e-73 244.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EKG11508.1 - 1.1e-15 57.8 0.0 6.8e-15 55.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG11508.1 - 3.9e-14 52.5 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG11508.1 - 6.1e-11 42.2 0.0 8.6e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG11508.1 - 5.2e-10 39.5 0.0 8.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG11508.1 - 1.2e-09 38.4 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG11508.1 - 8.4e-09 36.0 0.0 1.5e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG11508.1 - 4.4e-08 33.1 0.1 8.9e-08 32.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG11508.1 - 0.04 13.2 0.0 0.08 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.10 EKG11508.1 - 0.042 13.4 0.0 0.25 10.9 0.0 2.1 3 0 0 3 3 3 0 Hypothetical methyltransferase Methyltransf_28 PF02636.12 EKG11508.1 - 0.068 12.5 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase E1_dh PF00676.15 EKG11509.1 - 4.8e-89 298.0 0.0 5.7e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EKG11509.1 - 5.2e-05 22.8 0.6 0.00081 18.9 0.1 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EKG11509.1 - 0.043 12.7 0.0 0.14 11.0 0.0 1.8 2 1 1 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EKG11509.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain VHS PF00790.14 EKG11510.1 - 3.9e-35 120.5 0.7 8.1e-35 119.5 0.5 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EKG11510.1 - 1.6e-16 59.4 0.0 3e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG11510.1 - 9e-16 57.1 0.1 1.7e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKG11510.1 - 2.1e-13 49.5 0.0 3.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Pro-rich PF15240.1 EKG11510.1 - 0.00081 19.5 35.0 0.00081 19.5 24.3 3.7 2 1 2 4 4 4 1 Proline-rich UIM PF02809.15 EKG11510.1 - 0.0068 15.8 1.7 0.02 14.4 1.2 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Rrn6 PF10214.4 EKG11510.1 - 0.012 13.7 1.1 0.023 12.8 0.8 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HEAT_2 PF13646.1 EKG11510.1 - 0.02 15.1 1.1 0.17 12.1 0.2 2.6 2 1 0 2 2 2 0 HEAT repeats PTA_PTB PF01515.14 EKG11510.1 - 0.029 13.4 1.1 0.065 12.2 0.8 1.5 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase Diphthamide_syn PF01866.12 EKG11512.1 - 2.4e-53 181.3 0.0 4.1e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein PLA2_B PF01735.13 EKG11513.1 - 4.8e-186 618.7 7.6 5.6e-186 618.4 5.2 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain His_Phos_1 PF00300.17 EKG11514.1 - 6.4e-15 55.5 0.0 9.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SIS PF01380.17 EKG11515.1 - 9.5e-11 41.4 0.0 2.5e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EKG11515.1 - 0.00036 20.2 0.0 0.016 14.9 0.0 2.4 1 1 1 2 2 2 2 SIS domain ParA PF10609.4 EKG11516.1 - 2.7e-33 113.6 0.3 4.2e-33 113.0 0.2 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EKG11516.1 - 0.002 17.5 0.1 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 EKG11516.1 - 0.053 13.1 0.0 0.087 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Titin_Z PF09042.6 EKG11516.1 - 0.07 12.7 0.1 1 9.0 0.3 2.2 2 0 0 2 2 2 0 Titin Z AATF-Che1 PF13339.1 EKG11517.1 - 9e-29 100.2 4.5 9e-29 100.2 3.1 2.2 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EKG11517.1 - 1.5e-27 95.4 0.1 6.9e-27 93.3 0.1 2.2 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal DUF3347 PF11827.3 EKG11517.1 - 0.31 11.0 6.3 0.55 10.2 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF572 PF04502.8 EKG11518.1 - 0.033 13.4 8.5 0.036 13.2 5.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) UBA PF00627.26 EKG11519.1 - 8.8e-09 34.9 0.0 1.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EKG11519.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain HTH_8 PF02954.14 EKG11519.1 - 0.12 11.9 1.5 1.2 8.7 0.6 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family p450 PF00067.17 EKG11520.1 - 2.6e-37 128.4 0.3 3.1e-37 128.1 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 PH PF00169.24 EKG11521.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 PH domain Spectrin PF00435.16 EKG11521.1 - 2.5 8.4 6.1 1.7 8.9 0.2 2.9 2 2 1 3 3 3 0 Spectrin repeat Arrestin_N PF00339.24 EKG11522.1 - 9.6e-14 51.4 0.0 9.6e-13 48.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKG11522.1 - 2.1e-12 47.3 0.0 3e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EKG11522.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like WD40 PF00400.27 EKG11523.1 - 1.4e-21 75.5 8.7 1.7e-06 27.6 0.4 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat IKI3 PF04762.7 EKG11523.1 - 2.1e-05 22.5 0.0 0.00064 17.6 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.11 EKG11523.1 - 0.00018 19.9 0.0 0.00033 19.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 EKG11523.1 - 0.00062 19.5 0.0 0.0072 16.0 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EKG11523.1 - 0.0057 16.2 0.1 1.5 8.6 0.0 3.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EKG11523.1 - 0.064 13.5 0.1 44 4.5 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain DUF1273 PF06908.6 EKG11523.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Macin PF14865.1 EKG11523.1 - 0.19 11.8 0.3 0.54 10.3 0.1 1.8 2 0 0 2 2 2 0 Macin EF_assoc_2 PF08356.7 EKG11524.1 - 8.2e-36 121.6 0.0 1.7e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Miro PF08477.8 EKG11524.1 - 3.6e-35 121.0 0.0 1e-17 64.7 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EKG11524.1 - 1.5e-30 104.3 0.1 2.9e-30 103.3 0.1 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EKG11524.1 - 3.5e-23 81.7 0.0 3e-14 52.7 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EKG11524.1 - 3.4e-10 39.8 0.0 0.00018 21.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EKG11524.1 - 1.5e-07 31.6 0.3 0.0027 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_7 PF13499.1 EKG11524.1 - 3.5e-07 30.2 0.8 0.001 19.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.18 EKG11524.1 - 4.9e-07 29.7 0.7 0.049 13.4 0.1 2.9 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 EKG11524.1 - 1.6e-05 25.0 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKG11524.1 - 1.6e-05 24.3 0.0 0.018 14.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_6 PF13405.1 EKG11524.1 - 3.7e-05 23.2 2.7 0.11 12.4 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EKG11524.1 - 4.6e-05 22.4 1.4 0.064 12.5 0.0 2.8 2 0 0 2 2 2 2 EF hand DUF258 PF03193.11 EKG11524.1 - 6.4e-05 22.2 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKG11524.1 - 0.00023 21.4 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.17 EKG11524.1 - 0.00023 21.2 0.0 0.36 11.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase EF-hand_8 PF13833.1 EKG11524.1 - 0.00036 20.1 1.1 0.23 11.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair AAA_24 PF13479.1 EKG11524.1 - 0.00043 19.9 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EKG11524.1 - 0.00049 20.0 0.0 0.38 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EKG11524.1 - 0.00068 19.3 0.1 0.22 11.2 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 EKG11524.1 - 0.0007 18.5 0.1 0.86 8.3 0.0 2.3 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) DUF815 PF05673.8 EKG11524.1 - 0.0012 17.8 0.1 0.87 8.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.7 EKG11524.1 - 0.0018 17.9 0.0 2.1 7.9 0.0 2.8 3 0 0 3 3 2 1 NACHT domain Septin PF00735.13 EKG11524.1 - 0.0018 17.3 0.0 0.75 8.7 0.0 2.3 2 0 0 2 2 2 1 Septin Arch_ATPase PF01637.13 EKG11524.1 - 0.002 17.8 0.0 0.18 11.4 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EKG11524.1 - 0.0043 16.5 0.0 0.66 9.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EKG11524.1 - 0.0043 16.9 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKG11524.1 - 0.0087 15.4 0.0 1.7 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EKG11524.1 - 0.01 15.2 0.0 3.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EKG11524.1 - 0.012 15.1 0.1 0.46 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EKG11524.1 - 0.013 16.3 0.0 7.6 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.11 EKG11524.1 - 0.017 14.2 0.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AIG1 family AAA_18 PF13238.1 EKG11524.1 - 0.017 15.3 0.1 7.7 6.8 0.0 3.1 3 1 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.13 EKG11524.1 - 0.017 14.6 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EKG11524.1 - 0.028 14.6 0.2 4.7 7.4 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EKG11524.1 - 0.031 14.6 0.1 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EKG11524.1 - 0.047 13.1 0.8 5 6.5 0.2 3.7 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain EF-hand_10 PF14788.1 EKG11524.1 - 0.069 12.8 0.1 0.33 10.6 0.0 2.0 2 0 0 2 2 2 0 EF hand SMC_N PF02463.14 EKG11524.1 - 0.086 12.0 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SRPRB PF09439.5 EKG11524.1 - 0.093 11.9 0.1 1.6 7.9 0.0 2.4 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit EF-hand_5 PF13202.1 EKG11524.1 - 0.11 11.8 1.3 10 5.6 0.0 2.8 2 0 0 2 2 2 0 EF hand ATP_bind_1 PF03029.12 EKG11524.1 - 0.11 11.9 0.4 21 4.5 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 EKG11524.1 - 0.2 11.4 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Cupin_5 PF06172.6 EKG11526.1 - 6.4e-22 77.9 0.0 9.6e-14 51.4 0.0 2.4 2 1 0 2 2 2 2 Cupin superfamily (DUF985) Glyco_hydro_92 PF07971.7 EKG11527.1 - 3.9e-164 547.0 0.0 5.1e-164 546.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 ADH_N PF08240.7 EKG11528.1 - 2.6e-18 65.7 0.1 4.5e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aldedh PF00171.17 EKG11529.1 - 1.9e-33 115.5 0.6 2.4e-33 115.1 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Abhydrolase_6 PF12697.2 EKG11530.1 - 5.5e-12 46.0 2.1 5.5e-12 46.0 1.4 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG11530.1 - 2.5e-11 43.5 0.0 1.4e-10 41.0 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EKG11530.1 - 4e-06 25.6 0.0 6.1e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 EKG11530.1 - 0.0014 18.1 0.3 0.23 10.8 0.0 3.2 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EKG11530.1 - 0.0015 17.7 0.1 0.0066 15.6 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EKG11530.1 - 0.0024 17.5 0.1 0.015 14.8 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EKG11530.1 - 0.048 13.0 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 EKG11530.1 - 0.071 11.5 0.0 0.15 10.5 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UPF0227 PF05728.7 EKG11530.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) adh_short PF00106.20 EKG11531.1 - 2.3e-15 56.9 3.9 2.7e-15 56.6 1.3 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG11531.1 - 7.1e-09 35.5 1.3 8.2e-09 35.3 0.3 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EKG11531.1 - 6.8e-05 22.7 0.0 0.00012 21.9 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EKG11531.1 - 0.029 14.1 0.3 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 EKG11533.1 - 3.1e-32 111.7 0.0 3.6e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG11534.1 - 2e-43 148.5 0.0 2.6e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EKG11535.1 - 6.5e-16 58.0 0.1 1.7e-15 56.6 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG11535.1 - 2e-05 24.3 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 EKG11536.1 - 8.7e-41 139.7 50.8 2.1e-40 138.5 35.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG11536.1 - 8.5e-24 83.6 13.2 1.1e-23 83.2 9.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG11536.1 - 2.8e-14 52.5 10.3 2.8e-14 52.5 7.1 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter PEN-2 PF10251.4 EKG11536.1 - 1.5 9.0 5.3 3.1 8.0 0.1 3.1 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase ADH_zinc_N PF00107.21 EKG11538.1 - 6e-11 41.9 0.0 9.3e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG11538.1 - 5.2e-05 22.9 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 EKG11539.1 - 1.3e-76 257.4 0.0 3e-76 256.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 EKG11539.1 - 3.3e-76 256.3 0.0 5.5e-76 255.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Acyl_transf_1 PF00698.16 EKG11539.1 - 3.6e-54 184.2 0.5 1.1e-53 182.6 0.3 1.8 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EKG11539.1 - 6.9e-54 182.2 0.0 1.7e-53 180.9 0.0 1.7 1 0 0 1 1 1 1 KR domain Condensation PF00668.15 EKG11539.1 - 1.3e-53 181.8 0.0 2e-53 181.2 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 EKG11539.1 - 2e-53 181.4 0.1 4.6e-53 180.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EKG11539.1 - 2.4e-45 154.4 0.0 1.3e-44 152.0 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG11539.1 - 2.4e-29 101.5 0.0 9.4e-29 99.6 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EKG11539.1 - 1.3e-16 60.8 0.1 5.5e-16 58.8 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG11539.1 - 5.8e-14 52.3 0.0 2e-13 50.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG11539.1 - 2.6e-13 49.8 0.0 6.7e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG11539.1 - 2.2e-10 40.4 0.0 4.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EKG11539.1 - 3.4e-10 40.1 0.0 1.6e-09 37.9 0.0 2.2 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 EKG11539.1 - 2.6e-09 37.6 0.0 2.3e-08 34.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EKG11539.1 - 1.6e-06 27.3 0.0 3.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EKG11539.1 - 9.3e-05 22.6 0.1 0.00026 21.1 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EKG11539.1 - 0.00016 20.8 0.0 0.00037 19.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EKG11539.1 - 0.00028 20.3 0.0 0.00063 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EKG11539.1 - 0.00047 20.1 0.0 0.0036 17.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 EKG11539.1 - 0.065 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Med12 PF09497.5 EKG11540.1 - 2.3e-19 69.0 0.4 7.2e-19 67.5 0.3 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EKG11540.1 - 0.0049 15.4 0.3 2.8 6.3 0.2 2.5 1 1 1 2 2 2 2 Eukaryotic Mediator 12 subunit domain UPF0139 PF03669.8 EKG11541.1 - 3e-07 29.9 0.1 3.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) SUI1 PF01253.17 EKG11542.1 - 9.4e-30 102.2 5.7 1.3e-29 101.8 3.9 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EKG11542.1 - 0.11 12.5 0.6 0.32 11.0 0.1 1.8 1 1 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) DUF520 PF04461.8 EKG11542.1 - 0.12 12.2 3.3 0.14 11.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) FAD_binding_3 PF01494.14 EKG11545.1 - 1.6e-13 50.4 1.7 4.7e-11 42.3 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EKG11545.1 - 0.0025 16.7 0.0 0.0066 15.3 0.0 1.6 2 0 0 2 2 2 1 Squalene epoxidase Aldo_ket_red PF00248.16 EKG11547.1 - 2e-30 105.6 0.0 2.5e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_AsnC-type PF13404.1 EKG11547.1 - 0.3 10.6 1.4 31 4.2 0.0 3.6 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain CoA_transf_3 PF02515.12 EKG11548.1 - 9.1e-35 119.6 0.0 1.7e-33 115.5 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Aldedh PF00171.17 EKG11551.1 - 4.8e-129 430.6 0.4 5.4e-129 430.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EKG11551.1 - 0.073 12.2 0.0 0.28 10.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Sugar_tr PF00083.19 EKG11553.1 - 9.5e-109 363.9 24.0 1.1e-108 363.7 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11553.1 - 1.2e-20 73.5 56.1 5.3e-18 64.8 20.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EKG11555.1 - 1.4e-71 241.3 0.0 1.6e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EKG11556.1 - 3.9e-34 117.8 0.2 5.4e-34 117.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG11556.1 - 0.00056 19.7 2.4 0.0013 18.5 1.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EKG11557.1 - 2.6e-68 230.3 0.0 3.4e-68 229.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ECH PF00378.15 EKG11557.1 - 1.9e-39 135.2 0.2 3.2e-39 134.5 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding_C PF13193.1 EKG11557.1 - 0.0003 21.6 0.5 0.0013 19.5 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH_C PF13766.1 EKG11557.1 - 0.089 12.9 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region MBA1 PF07961.6 EKG11559.1 - 0.00053 18.8 0.0 0.0072 15.1 0.0 2.1 2 0 0 2 2 2 1 MBA1-like protein Tim44 PF04280.10 EKG11559.1 - 0.0011 18.9 0.1 0.075 13.0 0.0 2.4 2 0 0 2 2 2 1 Tim44-like domain Methyltrn_RNA_3 PF02598.12 EKG11560.1 - 5.7e-71 239.2 0.0 7.3e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EKG11560.1 - 0.075 12.9 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 SpoU rRNA Methylase family Cutinase PF01083.17 EKG11562.1 - 1.2e-29 103.3 2.9 1.7e-29 102.8 2.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EKG11562.1 - 0.0074 15.7 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 EKG11562.1 - 0.021 14.4 0.2 0.5 9.9 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) MAT_Alpha1 PF04769.7 EKG11565.1 - 2.6e-42 144.4 0.1 3.9e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Exo_endo_phos PF03372.18 EKG11567.1 - 1.1e-15 58.2 0.0 2.2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EKG11567.1 - 1.3e-15 57.0 0.0 3.8e-15 55.5 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF3669 PF12417.3 EKG11567.1 - 3.9e-11 42.5 0.0 1.2e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Zinc finger protein zf-GRF PF06839.7 EKG11567.1 - 0.003 17.4 0.7 0.0069 16.2 0.5 1.6 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 EKG11568.1 - 1.1e-46 157.5 2.2 1.1e-46 157.4 1.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Apc5 PF12862.2 EKG11569.1 - 1.5e-32 111.3 5.2 1.5e-32 111.3 3.6 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.1 EKG11569.1 - 0.019 15.2 1.3 25 5.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CIA30 PF08547.7 EKG11570.1 - 4.5e-42 143.5 0.0 5.4e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EKG11570.1 - 0.042 13.5 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) WW PF00397.21 EKG11570.1 - 0.05 13.4 0.1 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 WW domain Mito_carr PF00153.22 EKG11571.1 - 3.9e-64 212.3 4.5 7e-26 89.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SAICAR_synt PF01259.13 EKG11572.1 - 1.2e-85 286.6 0.0 1.4e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase SSF PF00474.12 EKG11573.1 - 1.3e-06 27.3 31.5 3.6e-05 22.5 21.8 2.5 1 1 0 1 1 1 1 Sodium:solute symporter family TPPK_C PF12555.3 EKG11573.1 - 0.023 14.4 2.4 0.023 14.4 1.6 3.9 2 1 2 4 4 4 0 Thiamine pyrophosphokinase C terminal RRM_1 PF00076.17 EKG11574.1 - 1e-12 47.4 0.0 1.4e-05 24.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG11574.1 - 1.4e-07 31.3 0.0 8.2e-06 25.7 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG11574.1 - 0.04 13.7 0.1 0.39 10.5 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PX PF00787.19 EKG11576.1 - 3.2e-27 94.5 0.0 4.2e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 PX domain Peptidase_C65 PF10275.4 EKG11577.1 - 1.6e-64 217.6 0.0 2.1e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 EKG11578.1 - 2.1e-21 76.1 0.7 4.4e-21 75.1 0.1 1.9 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EKG11578.1 - 6.7e-07 29.1 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EKG11578.1 - 0.0012 18.4 5.5 0.24 11.2 0.1 4.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKG11578.1 - 0.0022 17.8 0.2 1.4 8.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKG11578.1 - 0.018 14.6 3.1 0.072 12.7 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKG11578.1 - 0.03 14.1 1.3 0.2 11.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKG11578.1 - 0.046 13.6 0.2 0.046 13.6 0.2 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EKG11578.1 - 0.16 11.9 8.2 0.39 10.6 0.7 3.8 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKG11578.1 - 0.49 10.0 6.8 0.32 10.6 0.5 3.5 4 1 1 5 5 5 0 TPR repeat MIT PF04212.13 EKG11578.1 - 0.79 9.6 4.5 0.48 10.3 1.0 2.3 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain CWC25 PF12542.3 EKG11579.1 - 1.5e-24 86.2 1.3 1.5e-24 86.2 0.9 4.2 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.4 EKG11579.1 - 2.3e-15 56.3 9.2 2.3e-15 56.3 6.4 4.4 3 2 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 EKG11579.1 - 0.034 13.5 2.4 0.05 13.0 0.3 2.3 2 0 0 2 2 2 0 RNA dependent RNA polymerase Ras PF00071.17 EKG11580.1 - 2e-53 180.1 0.0 2.8e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG11580.1 - 3.6e-15 56.5 0.0 5.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG11580.1 - 5.5e-10 38.7 0.0 8.1e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG11580.1 - 0.00082 18.5 0.0 0.00088 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKG11580.1 - 0.0013 17.9 0.0 0.0027 16.9 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EKG11580.1 - 0.013 14.2 0.0 0.018 13.7 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Arch_ATPase PF01637.13 EKG11580.1 - 0.032 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 EKG11580.1 - 0.034 14.0 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EKG11580.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ribosomal_L21e PF01157.13 EKG11581.1 - 2.1e-18 65.9 1.9 7.2e-18 64.2 1.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Nexin_C PF08628.7 EKG11581.1 - 0.0032 17.5 0.1 0.0039 17.2 0.1 1.1 1 0 0 1 1 1 1 Sorting nexin C terminal Ribosomal_S4 PF00163.14 EKG11582.1 - 3.5e-30 104.2 1.2 6.4e-30 103.4 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EKG11582.1 - 2.7e-12 45.9 1.1 2.7e-12 45.9 0.8 2.6 3 0 0 3 3 3 1 S4 domain DUF2076 PF09849.4 EKG11583.1 - 2.8e-09 37.4 12.9 3.1e-09 37.2 8.9 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EKG11583.1 - 0.00026 20.8 3.4 0.00039 20.2 2.4 1.3 1 0 0 1 1 1 1 CHCH domain Med2 PF11214.3 EKG11583.1 - 0.017 15.1 0.1 0.023 14.7 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF605 PF04652.11 EKG11583.1 - 0.91 8.8 13.3 1.1 8.6 9.2 1.1 1 0 0 1 1 1 0 Vta1 like FAP PF07174.6 EKG11583.1 - 1.9 7.6 18.7 2.4 7.3 13.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Ribosomal_S27e PF01667.12 EKG11584.1 - 2.6e-29 100.5 7.2 3.3e-29 100.1 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EKG11584.1 - 0.012 15.4 1.4 0.014 15.2 1.0 1.2 1 0 0 1 1 1 0 IBR domain zf-CSL PF05207.8 EKG11584.1 - 0.044 13.3 1.1 0.082 12.4 0.7 1.5 1 0 0 1 1 1 0 CSL zinc finger DeoC PF01791.4 EKG11585.1 - 2.2e-41 141.7 4.4 2.6e-41 141.4 3.1 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase TroA PF01297.12 EKG11585.1 - 0.041 13.1 0.1 0.43 9.7 0.0 2.0 1 1 1 2 2 2 0 Periplasmic solute binding protein family DUF3216 PF11505.3 EKG11585.1 - 0.081 12.7 0.0 0.38 10.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3216) Rogdi_lz PF10259.4 EKG11586.1 - 0.082 12.0 2.5 5.2 6.1 0.0 2.8 2 1 1 3 3 3 0 Rogdi leucine zipper containing protein SURF1 PF02104.10 EKG11587.1 - 5.7e-66 222.3 0.1 8e-66 221.8 0.0 1.2 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 EKG11588.1 - 2.7e-46 158.6 10.0 3e-46 158.5 6.9 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EKG11588.1 - 8.3e-07 29.1 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EKG11588.1 - 0.00036 20.5 0.0 0.00058 19.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKG11588.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EKG11588.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated COPI_C PF06957.6 EKG11588.1 - 0.75 8.2 4.2 1.1 7.7 2.9 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 EKG11588.1 - 2.1 6.1 6.3 2.3 6.0 4.4 1.1 1 0 0 1 1 1 0 Nop14-like family CMS1 PF14617.1 EKG11589.1 - 7e-65 218.5 3.2 9e-65 218.2 2.2 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EKG11589.1 - 0.026 14.0 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase NAD_Gly3P_dh_C PF07479.9 EKG11589.1 - 0.048 13.3 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Kri1 PF05178.7 EKG11589.1 - 3.2 8.0 11.6 9.6 6.5 0.1 2.4 2 1 0 2 2 2 0 KRI1-like family Ras PF00071.17 EKG11590.1 - 1.4e-54 183.8 0.0 1.6e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG11590.1 - 2e-17 63.8 0.0 3.1e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG11590.1 - 9.3e-08 31.4 0.0 1.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG11590.1 - 0.0014 18.1 0.0 0.0047 16.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain UBX PF00789.15 EKG11591.1 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 EKG11591.1 - 0.091 12.8 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like PVL_ORF50 PF07768.6 EKG11591.1 - 0.16 11.9 6.1 0.3 11.0 4.2 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family YqzE PF14038.1 EKG11591.1 - 0.34 10.7 2.5 0.73 9.6 1.7 1.5 1 0 0 1 1 1 0 YqzE-like protein TFIIA PF03153.8 EKG11591.1 - 8 6.2 15.7 11 5.7 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_3 PF13640.1 EKG11592.1 - 1.4e-09 38.3 0.6 4.4e-08 33.5 0.4 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EKG11592.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.3 EKG11593.1 - 3.9e-37 127.7 0.0 5.7e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG11593.1 - 1.7e-07 31.0 10.5 3.1e-07 30.1 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_PEP_C PF04513.7 EKG11594.1 - 0.00039 20.2 2.2 0.042 13.6 0.2 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3552 PF12072.3 EKG11594.1 - 0.0034 16.6 13.6 0.089 12.0 2.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3552) BLOC1_2 PF10046.4 EKG11594.1 - 0.0065 16.5 1.3 0.0065 16.5 0.9 2.4 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.6 EKG11594.1 - 0.02 14.5 9.6 0.047 13.3 0.4 2.9 3 1 0 3 3 2 0 Spc24 subunit of Ndc80 Reo_sigmaC PF04582.7 EKG11594.1 - 0.036 13.2 1.5 0.57 9.2 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HlyD PF00529.15 EKG11594.1 - 0.041 13.1 9.1 0.42 9.8 0.7 2.2 2 0 0 2 2 2 0 HlyD family secretion protein Allexi_40kDa PF05549.6 EKG11594.1 - 0.066 12.5 1.6 0.15 11.3 0.2 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein Spc7 PF08317.6 EKG11594.1 - 0.074 11.7 11.0 0.34 9.5 2.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein COG2 PF06148.6 EKG11594.1 - 0.075 12.8 6.7 2.9 7.7 0.4 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fez1 PF06818.10 EKG11594.1 - 0.11 12.5 18.3 0.045 13.7 6.7 2.5 2 1 1 3 3 2 0 Fez1 IncA PF04156.9 EKG11594.1 - 0.11 12.1 20.4 0.1 12.1 2.7 2.8 1 1 2 3 3 3 0 IncA protein Cluap1 PF10234.4 EKG11594.1 - 0.12 11.5 8.8 0.37 9.9 1.1 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.4 EKG11594.1 - 0.12 11.2 15.4 0.054 12.4 1.2 3.0 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EKG11594.1 - 0.16 11.4 11.0 0.92 9.0 1.8 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 EKG11594.1 - 0.35 11.0 3.3 0.55 10.4 0.1 2.6 1 1 1 2 2 2 0 Syntaxin Lge1 PF11488.3 EKG11594.1 - 0.37 11.0 8.3 3.7 7.8 0.3 3.1 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 DUF342 PF03961.8 EKG11594.1 - 0.43 8.9 3.4 0.7 8.2 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mod_r PF07200.8 EKG11594.1 - 0.62 9.9 11.7 1 9.2 2.4 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3153 PF11353.3 EKG11594.1 - 0.86 8.9 4.1 4.3 6.7 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) AAA_13 PF13166.1 EKG11594.1 - 1.2 7.4 8.3 0.21 10.0 2.7 1.9 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.6 EKG11594.1 - 1.3 8.7 18.9 0.3 10.8 0.9 3.2 1 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF848 PF05852.6 EKG11594.1 - 1.4 8.7 6.0 2.7 7.8 0.4 2.5 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch PF05377.6 EKG11594.1 - 1.4 8.8 8.5 11 6.0 0.2 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 EKG11594.1 - 1.8 8.4 14.3 0.15 11.9 0.8 3.1 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EKG11594.1 - 3.2 6.9 11.4 0.98 8.5 0.6 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 EKG11594.1 - 3.3 7.5 16.9 1.1 9.0 1.4 3.7 3 1 1 4 4 4 0 Prefoldin subunit FlxA PF14282.1 EKG11594.1 - 4.4 7.2 9.9 9 6.2 0.4 3.2 3 1 1 4 4 4 0 FlxA-like protein FUSC PF04632.7 EKG11594.1 - 5.1 5.3 9.2 7.2 4.9 6.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 EKG11594.1 - 5.7 7.3 7.5 13 6.1 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EKG11594.1 - 6.4 6.2 8.4 37 3.7 0.2 3.8 3 2 1 4 4 4 0 Phage minor structural protein GP20 FemAB PF02388.11 EKG11594.1 - 7.3 5.1 7.5 0.64 8.6 0.6 2.3 1 1 2 3 3 3 0 FemAB family DUF4201 PF13870.1 EKG11594.1 - 8.3 5.8 10.4 1.1 8.6 0.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) GvpK PF05121.7 EKG11594.1 - 9 6.1 12.6 0.2 11.5 0.6 3.5 3 1 1 4 4 4 0 Gas vesicle protein K Ribosomal_L37e PF01907.14 EKG11595.1 - 1.7e-26 91.7 11.1 3.5e-26 90.7 7.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EKG11595.1 - 0.012 15.3 1.5 0.023 14.5 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn_clus PF00172.13 EKG11596.1 - 8.3e-08 32.0 9.8 1.3e-07 31.4 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EKG11596.1 - 0.0037 15.9 0.2 0.0052 15.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TP_methylase PF00590.15 EKG11597.1 - 1.7e-45 155.3 0.2 2.6e-45 154.7 0.1 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EKG11597.1 - 8.3e-14 51.6 0.0 1.4e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EKG11597.1 - 5.8e-09 35.1 0.0 2.4e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EKG11597.1 - 0.00011 21.1 0.0 0.00025 19.9 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central SUR7 PF06687.7 EKG11599.1 - 3.6e-33 114.9 4.2 4.5e-33 114.6 2.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EKG11599.1 - 0.00061 19.5 14.1 0.00061 19.5 9.8 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF373 PF04123.8 EKG11599.1 - 0.0036 16.3 1.0 0.0052 15.8 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF373) Clc-like PF07062.7 EKG11599.1 - 5.6 6.1 15.1 0.3 10.2 6.3 2.0 2 1 0 2 2 2 0 Clc-like Rogdi_lz PF10259.4 EKG11600.1 - 2.9e-73 246.3 0.0 3.4e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein SUR7 PF06687.7 EKG11603.1 - 3.2e-28 98.7 13.4 4e-28 98.4 9.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family NfeD PF01957.13 EKG11603.1 - 4.6 7.3 10.3 0.1 12.7 1.8 2.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Ribosomal_S4e PF00900.15 EKG11604.1 - 3e-32 110.1 0.2 6.6e-32 109.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e S4 PF01479.20 EKG11604.1 - 2.2e-06 26.9 0.0 4.2e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EKG11604.1 - 0.0022 17.6 0.6 0.0022 17.6 0.4 2.9 3 0 0 3 3 3 1 KOW motif GAS PF13851.1 EKG11605.1 - 0.12 11.5 42.4 0.24 10.5 13.8 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 EKG11605.1 - 1.2 6.7 51.9 1.6 6.3 36.0 1.1 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EKG11605.1 - 6.7 5.7 16.4 7.5 5.6 2.1 3.0 2 1 1 4 4 4 0 Reovirus sigma C capsid protein RdRP PF05183.7 EKG11606.1 - 4.5e-180 600.1 0.0 6.1e-180 599.7 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 EKG11606.1 - 0.019 14.9 0.0 0.77 9.7 0.0 3.2 4 0 0 4 4 4 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG11606.1 - 0.13 11.9 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EKG11607.1 - 5.5e-06 25.3 0.3 5.8e-06 25.2 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 EKG11608.1 - 1.4e-14 54.3 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Recep_L_domain PF01030.19 EKG11609.1 - 0.0022 17.9 0.1 0.58 10.1 0.0 3.7 1 1 2 3 3 3 2 Receptor L domain DUF46 PF01864.12 EKG11610.1 - 0.044 13.6 0.1 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 MFS_1 PF07690.11 EKG11611.1 - 3.8e-10 39.0 16.9 4.6e-10 38.7 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG11611.1 - 0.00039 18.9 8.7 0.13 10.6 0.0 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein Phage_Orf51 PF06194.6 EKG11612.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 Fungal_trans PF04082.13 EKG11613.1 - 5e-06 25.5 0.0 8.2e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EKG11614.1 - 6.2e-57 193.1 0.0 1e-56 192.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Alpha_L_fucos PF01120.12 EKG11614.1 - 2.7e-29 102.1 0.1 5.7e-29 101.1 0.1 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.20 EKG11614.1 - 4.3e-11 42.7 0.4 1.5e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 F5/8 type C domain Ribonuclease PF00545.15 EKG11616.1 - 8.9e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.3 EKG11617.1 - 4.5e-15 55.9 5.4 7.2e-15 55.2 3.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ZZ PF00569.12 EKG11618.1 - 0.56 9.7 3.7 0.17 11.4 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, ZZ type FAD_binding_3 PF01494.14 EKG11620.1 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EKG11620.1 - 1.5e-06 27.5 0.4 0.0011 18.0 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EKG11620.1 - 2.7e-05 23.2 3.1 0.014 14.3 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG11620.1 - 0.00029 21.1 2.3 0.0035 17.7 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG11620.1 - 0.0023 17.0 0.1 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG11620.1 - 0.0035 17.3 0.4 0.0099 15.8 0.1 2.0 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EKG11620.1 - 0.0039 16.7 2.2 0.36 10.3 0.1 2.3 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_L28e PF01778.12 EKG11620.1 - 0.017 15.5 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L28e protein family Trp_halogenase PF04820.9 EKG11620.1 - 0.023 13.3 2.0 1.2 7.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EKG11620.1 - 0.034 13.0 0.5 3.8 6.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EKG11620.1 - 0.078 12.8 1.5 0.52 10.1 1.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG11620.1 - 0.11 12.5 0.2 0.27 11.2 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EKG11621.1 - 2.2e-13 49.6 1.1 2.7e-12 46.1 0.0 2.6 3 1 0 3 3 3 1 Fungal specific transcription factor domain PTS_2-RNA PF01885.11 EKG11621.1 - 0.0087 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Herpes_U44 PF04533.8 EKG11621.1 - 0.17 11.1 0.1 0.51 9.5 0.0 1.7 2 0 0 2 2 2 0 Herpes virus U44 protein FA_desaturase PF00487.19 EKG11622.1 - 2.8e-33 115.4 23.0 4.2e-33 114.8 15.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EKG11622.1 - 8.6e-06 25.8 0.0 2.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) AAA_34 PF13872.1 EKG11622.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Sigma70_r3 PF04539.11 EKG11622.1 - 0.15 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Sigma-70 region 3 MFS_1 PF07690.11 EKG11623.1 - 7e-29 100.6 29.0 1.1e-28 99.9 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Tmemb_161AB PF10268.4 EKG11623.1 - 0.29 9.5 2.1 1.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Predicted transmembrane protein 161AB DIOX_N PF14226.1 EKG11624.1 - 3e-18 66.4 0.0 6.1e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG11624.1 - 8.8e-16 58.0 0.0 1.6e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EKG11625.1 - 9.9e-26 90.5 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG11625.1 - 2.6e-23 82.1 0.0 1.9e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Amidohydro_5 PF13594.1 EKG11626.1 - 5.5e-11 42.1 0.3 1.2e-10 41.0 0.2 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG11626.1 - 5e-10 39.5 0.0 6.3e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG11626.1 - 0.00031 20.8 0.2 0.0011 19.0 0.0 1.6 1 1 1 2 2 2 1 Amidohydrolase Xan_ur_permease PF00860.15 EKG11627.1 - 3.8e-30 104.6 26.2 2e-29 102.2 18.2 1.8 1 1 0 1 1 1 1 Permease family Rpp20 PF12328.3 EKG11628.1 - 3.1e-38 130.6 4.5 3.6e-38 130.4 3.1 1.0 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EKG11628.1 - 3.3e-17 61.8 0.2 5e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 Alba BPL_LplA_LipB PF03099.14 EKG11629.1 - 1.5e-15 57.2 0.0 2.8e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ACT_4 PF13291.1 EKG11630.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 ACT domain Slu7 PF11708.3 EKG11631.1 - 2.8e-81 272.8 16.0 2.8e-81 272.8 11.1 2.5 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EKG11631.1 - 0.014 15.0 0.7 0.028 14.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Sigma70_r2 PF04542.9 EKG11631.1 - 0.047 13.3 0.5 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 region 2 zf-CCHC PF00098.18 EKG11631.1 - 0.1 12.5 1.1 0.21 11.5 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EKG11631.1 - 1.1 8.8 4.2 2.1 7.8 2.9 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DNA_pol_B PF00136.16 EKG11632.1 - 4e-97 325.9 0.0 6.1e-97 325.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EKG11632.1 - 1.2e-24 86.7 0.3 4e-14 52.2 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain AA_permease_2 PF13520.1 EKG11634.1 - 1.8e-62 211.2 26.6 1.8e-62 211.2 18.4 1.7 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.16 EKG11634.1 - 1.2e-18 66.8 11.6 1.2e-18 66.8 8.0 3.0 4 1 0 4 4 4 1 Amino acid permease bZIP_1 PF00170.16 EKG11635.1 - 8.2e-09 35.2 9.5 2e-08 34.0 6.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG11635.1 - 2.1e-05 24.2 9.8 8.7e-05 22.2 6.8 2.0 1 1 0 1 1 1 1 Basic region leucine zipper SecD-TM1 PF13721.1 EKG11635.1 - 0.12 12.5 0.2 0.2 11.9 0.1 1.2 1 0 0 1 1 1 0 SecD export protein N-terminal TM region bZIP_Maf PF03131.12 EKG11635.1 - 0.19 12.0 6.2 0.41 10.9 4.3 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF605 PF04652.11 EKG11635.1 - 5.9 6.1 13.4 0.035 13.5 3.4 1.5 2 0 0 2 2 2 0 Vta1 like Zn_clus PF00172.13 EKG11636.1 - 9.6e-07 28.6 9.2 1.5e-06 28.0 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UxaC PF02614.9 EKG11636.1 - 0.074 11.6 0.0 0.09 11.3 0.0 1.3 1 0 0 1 1 1 0 Glucuronate isomerase SET PF00856.23 EKG11637.1 - 7.9e-22 78.2 0.6 7.9e-22 78.2 0.4 4.1 3 3 0 3 3 3 1 SET domain ABC1 PF03109.11 EKG11638.1 - 3e-17 62.6 0.0 7.8e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 ABC1 family RhoGAP PF00620.22 EKG11639.1 - 3.3e-50 169.6 0.0 2.6e-49 166.7 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EKG11639.1 - 9.2e-10 38.5 0.5 9.2e-10 38.5 0.4 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain LOH1CR12 PF10158.4 EKG11639.1 - 0.15 11.8 3.7 0.12 12.1 1.2 1.9 2 0 0 2 2 2 0 Tumour suppressor protein DUF3810 PF12725.2 EKG11639.1 - 0.28 10.0 1.6 0.45 9.3 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3135 PF11333.3 EKG11639.1 - 1.4 9.0 6.3 2 8.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) V_ATPase_I PF01496.14 EKG11639.1 - 6.7 4.4 5.7 7 4.3 3.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Pyridox_oxidase PF01243.15 EKG11640.1 - 4.4e-13 49.0 0.0 2.7e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EKG11640.1 - 0.052 13.3 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Yae1_N PF09811.4 EKG11641.1 - 1.1e-10 40.8 0.3 1.8e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal p450 PF00067.17 EKG11642.1 - 8.8e-43 146.4 0.0 1.4e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AAA_23 PF13476.1 EKG11643.1 - 0.076 13.3 2.8 0.13 12.5 1.9 1.3 1 0 0 1 1 1 0 AAA domain Coatomer_b_Cpla PF14806.1 EKG11643.1 - 0.18 11.5 0.5 0.35 10.5 0.4 1.4 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform OPT PF03169.10 EKG11644.1 - 9e-86 288.6 46.0 1.1e-85 288.4 31.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SCO1-SenC PF02630.9 EKG11645.1 - 6.1e-61 205.0 0.0 8.1e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EKG11645.1 - 6.7e-09 35.4 0.0 1.6e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EKG11645.1 - 4.9e-06 26.5 0.0 9.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EKG11645.1 - 0.0015 18.0 0.0 0.018 14.5 0.0 2.2 1 1 0 1 1 1 1 Redoxin HlyIII PF03006.15 EKG11647.1 - 6.9e-26 91.0 10.8 8.6e-26 90.7 7.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Cbl_N2 PF02761.9 EKG11650.1 - 0.066 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain zf-DHHC PF01529.15 EKG11651.1 - 2.2e-35 121.6 0.1 5e-35 120.4 0.0 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase PRA1 PF03208.14 EKG11651.1 - 0.058 12.7 3.0 0.98 8.7 0.2 2.3 2 0 0 2 2 2 0 PRA1 family protein Yip1 PF04893.12 EKG11651.1 - 0.066 12.7 7.7 0.066 12.7 0.6 2.2 2 0 0 2 2 2 0 Yip1 domain F-box PF00646.28 EKG11653.1 - 0.24 11.1 2.2 0.49 10.1 0.1 2.4 2 0 0 2 2 2 0 F-box domain PBP1_TM PF14812.1 EKG11653.1 - 3.3 8.0 6.1 6.8 7.0 4.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_11 PF00457.12 EKG11654.1 - 1.6e-79 265.5 24.0 1.9e-79 265.3 16.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF3405 PF11885.3 EKG11655.1 - 6.1e-97 324.9 12.5 8.8e-97 324.3 8.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Lactamase_B PF00753.22 EKG11657.1 - 4e-13 49.4 3.3 5e-13 49.1 2.3 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG11657.1 - 0.024 14.1 0.9 0.038 13.5 0.6 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Fructosamin_kin PF03881.9 EKG11658.1 - 1.4e-76 257.2 0.0 1.6e-76 257.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EKG11658.1 - 0.00063 19.5 0.0 0.00097 18.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EKG11658.1 - 0.0067 15.1 0.0 0.0097 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) DUF3433 PF11915.3 EKG11659.1 - 6e-36 122.4 15.0 6e-24 84.0 3.5 3.5 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) DEAD PF00270.24 EKG11660.1 - 7.8e-43 145.8 0.0 1.3e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG11660.1 - 3e-22 78.2 0.1 1.2e-21 76.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKG11660.1 - 1.3e-06 27.4 0.0 1.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain PPPI_inhib PF14895.1 EKG11660.1 - 0.036 12.8 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor DUF1253 PF06862.7 EKG11660.1 - 0.1 10.9 0.0 7.3 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Ion_trans_2 PF07885.11 EKG11661.1 - 2.4e-27 94.4 16.5 2.4e-17 62.4 3.5 2.2 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 EKG11661.1 - 0.014 14.6 1.8 0.021 14.0 1.0 1.5 1 1 0 1 1 1 0 Ion transport protein SGL PF08450.7 EKG11662.1 - 1.4e-28 99.9 0.1 2.6e-28 99.0 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EKG11662.1 - 2.1e-06 27.5 0.0 2.6e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 Arylesterase Str_synth PF03088.11 EKG11662.1 - 0.00023 21.1 0.0 0.00086 19.3 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Kelch_6 PF13964.1 EKG11662.1 - 0.039 14.1 0.4 0.3 11.3 0.0 2.7 2 1 0 2 2 2 0 Kelch motif Reg_prop PF07494.6 EKG11662.1 - 0.052 13.5 0.6 3.1 8.1 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller Kelch_1 PF01344.20 EKG11662.1 - 0.077 12.5 0.1 0.84 9.2 0.0 2.4 2 0 0 2 2 2 0 Kelch motif NHL PF01436.16 EKG11662.1 - 0.3 11.1 2.7 3.6 7.7 0.0 3.5 3 0 0 3 3 3 0 NHL repeat Glyco_hydro_16 PF00722.16 EKG11663.1 - 3.8e-41 140.4 3.7 6.7e-41 139.6 2.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF4585 PF15232.1 EKG11664.1 - 0.0024 17.6 0.3 0.0043 16.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4585) Abhydrolase_6 PF12697.2 EKG11665.1 - 2.9e-20 73.1 13.6 3.8e-20 72.7 9.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG11665.1 - 3.9e-09 36.4 0.1 4.9e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG11665.1 - 8.3e-08 32.1 1.4 1.6e-07 31.1 1.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family OPT PF03169.10 EKG11666.1 - 3.4e-147 491.5 44.6 4.2e-147 491.2 30.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein WD40 PF00400.27 EKG11667.1 - 1.2e-14 53.4 7.4 4e-06 26.5 0.3 4.6 5 1 0 5 5 5 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EKG11667.1 - 0.0067 15.2 0.0 0.047 12.4 0.0 1.9 1 1 0 1 1 1 1 Nup133 N terminal like Gryzun-like PF12742.2 EKG11667.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking IncA PF04156.9 EKG11667.1 - 0.03 13.9 0.6 0.051 13.1 0.4 1.3 1 0 0 1 1 1 0 IncA protein DUF3312 PF11768.3 EKG11667.1 - 0.039 12.1 0.0 0.068 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF904 PF06005.7 EKG11667.1 - 0.15 12.3 5.9 0.27 11.5 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) FSH1 PF03959.8 EKG11668.1 - 2.5e-65 219.8 0.0 3.3e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EKG11668.1 - 8.7e-08 32.3 0.0 5.6e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG11668.1 - 1.3e-05 24.9 0.1 2e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG11668.1 - 0.019 14.4 0.5 6 6.2 0.0 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase DLH PF01738.13 EKG11668.1 - 0.02 14.2 0.1 0.29 10.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family PCI PF01399.22 EKG11669.1 - 2.3e-21 76.0 0.0 7.6e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 PCI domain Asp_Glu_race_2 PF14669.1 EKG11669.1 - 3.9e-05 23.1 1.0 0.02 14.2 0.0 2.3 2 0 0 2 2 2 2 Putative aspartate racemase PCI_Csn8 PF10075.4 EKG11669.1 - 0.0047 16.6 0.2 0.027 14.2 0.0 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 RPE65 PF03055.10 EKG11671.1 - 7.8e-136 453.4 0.0 1.1e-135 453.0 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein PPI_Ypi1 PF07491.6 EKG11671.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor SQS_PSY PF00494.14 EKG11672.1 - 5.8e-66 222.5 0.5 7.6e-66 222.1 0.3 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF5 PF04855.7 EKG11672.1 - 0.0079 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Amino_oxidase PF01593.19 EKG11673.1 - 1.3e-17 64.0 0.2 6.7e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EKG11673.1 - 4e-15 55.5 1.5 1.7e-07 30.4 0.1 3.2 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG11673.1 - 9.2e-15 54.4 0.2 2.7e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG11673.1 - 2e-06 27.8 0.1 6.3e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG11673.1 - 8.2e-06 24.5 1.4 0.0054 15.2 1.4 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EKG11673.1 - 1.1e-05 24.5 6.7 4.2e-05 22.5 3.5 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EKG11673.1 - 0.00011 21.4 5.0 0.00027 20.1 3.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG11673.1 - 0.00016 21.8 0.3 0.0016 18.5 0.2 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG11673.1 - 0.0033 17.8 3.6 0.01 16.1 1.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG11673.1 - 0.0059 15.5 3.4 0.0059 15.5 2.4 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EKG11673.1 - 0.013 14.6 0.9 0.021 13.9 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EKG11673.1 - 0.029 13.4 0.8 0.056 12.5 0.5 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EKG11673.1 - 0.067 12.7 1.3 0.11 12.0 0.9 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EKG11673.1 - 0.084 12.6 1.3 0.22 11.3 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EKG11673.1 - 0.096 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EKG11673.1 - 0.11 12.1 2.7 0.18 11.4 1.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Strep_67kDa_ant PF06100.6 EKG11673.1 - 0.12 10.6 0.0 1.3 7.3 0.0 2.0 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family GDI PF00996.13 EKG11673.1 - 0.15 10.3 0.1 7.2 4.7 0.0 2.2 2 0 0 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.9 EKG11673.1 - 0.68 8.4 4.8 1.1 7.8 1.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Bac_rhodopsin PF01036.13 EKG11674.1 - 2.6e-61 206.7 17.6 3.3e-61 206.4 12.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4063 PF13272.1 EKG11674.1 - 0.071 12.9 1.6 0.16 11.8 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4063) Acatn PF13000.2 EKG11676.1 - 2.4e-155 518.1 22.3 1.2e-78 264.9 5.7 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 AhpC-TSA PF00578.16 EKG11677.1 - 1.4e-37 128.1 0.0 1.8e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKG11677.1 - 1.6e-17 63.3 0.0 2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EKG11677.1 - 3.4e-14 52.1 0.2 6.2e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Myb_DNA-binding PF00249.26 EKG11678.1 - 1.4e-15 57.0 3.1 1.6e-09 37.6 0.1 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG11678.1 - 2.8e-10 40.1 0.6 0.00019 21.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Annexin PF00191.15 EKG11680.1 - 3.6e-18 65.2 5.0 2.3e-06 27.4 0.0 4.5 4 0 0 4 4 4 4 Annexin SR-25 PF10500.4 EKG11680.1 - 4.4e-05 23.0 9.0 4.4e-05 23.0 6.2 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Crystallin PF00525.13 EKG11681.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal Cu-oxidase PF00394.17 EKG11682.1 - 1.8e-28 99.4 0.1 2.8e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG11682.1 - 2e-05 24.1 0.2 5.2e-05 22.7 0.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase MFS_1 PF07690.11 EKG11685.1 - 6.9e-37 126.9 27.5 1.2e-27 96.6 8.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG11685.1 - 5.1e-15 54.9 8.4 5.1e-15 54.9 5.9 2.9 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EKG11685.1 - 0.0018 16.5 3.0 0.0035 15.6 2.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BacA PF02673.13 EKG11686.1 - 0.13 11.4 0.1 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacitracin resistance protein BacA SPT16 PF08644.6 EKG11687.1 - 2.2e-57 193.1 0.2 2.2e-57 193.1 0.1 2.4 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EKG11687.1 - 3.1e-54 182.9 0.3 2e-53 180.2 0.2 2.5 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EKG11687.1 - 2.7e-22 79.3 0.0 4.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EKG11687.1 - 4.1e-22 77.9 0.1 1.7e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.22 EKG11688.1 - 6.1e-18 64.3 4.2 1.8e-14 53.2 0.1 3.0 3 1 0 3 3 3 2 Mitochondrial carrier protein ANTH PF07651.11 EKG11692.1 - 2.4e-75 252.8 1.7 1.2e-74 250.5 0.0 2.7 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 EKG11692.1 - 2.4e-65 219.1 7.7 2.4e-65 219.1 5.3 5.0 4 1 1 5 5 5 2 I/LWEQ domain ENTH PF01417.15 EKG11692.1 - 0.00025 20.8 0.0 0.0016 18.2 0.0 2.5 1 0 0 1 1 1 1 ENTH domain TcdB_N PF12918.2 EKG11692.1 - 0.0031 17.5 1.4 0.0031 17.5 1.0 3.6 4 0 0 4 4 4 1 TcdB toxin N-terminal helical domain Cellulase PF00150.13 EKG11693.1 - 1.2e-39 136.1 7.0 1.2e-39 136.1 4.9 1.9 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 EKG11693.1 - 5.5e-21 74.1 0.2 5.5e-21 74.1 0.1 3.1 4 0 0 4 4 4 1 Carbohydrate binding domain X2 RRM_6 PF14259.1 EKG11694.1 - 1e-07 31.7 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG11694.1 - 0.00094 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG11694.1 - 0.001 18.8 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EKG11696.1 - 1.2e-26 91.5 15.7 4e-06 26.4 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.1 EKG11696.1 - 0.00032 20.8 1.9 0.66 10.3 0.0 3.2 3 0 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 EKG11696.1 - 0.0051 15.1 1.1 0.39 8.9 0.0 3.2 3 1 0 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EKG11696.1 - 0.013 14.2 0.0 9.1 4.8 0.0 3.4 2 1 2 4 4 4 0 Nup133 N terminal like Glyco_hydro_7 PF00840.15 EKG11699.1 - 3.9e-103 345.1 12.3 4.5e-103 344.9 8.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Fer4_8 PF13183.1 EKG11699.1 - 1.4 8.9 6.8 27 4.8 0.0 2.9 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKG11699.1 - 1.6 9.0 5.4 8.2 6.7 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Glyco_hydro_7 PF00840.15 EKG11700.1 - 8.4e-69 232.0 0.4 9.6e-69 231.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_3 PF00933.16 EKG11701.1 - 2.4e-53 181.0 0.0 3e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG11701.1 - 4.3e-13 49.3 0.1 7.1e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain DUF4206 PF13901.1 EKG11702.1 - 0.12 11.9 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) EI24 PF07264.6 EKG11703.1 - 2.6e-06 27.0 5.5 6.7e-06 25.6 3.8 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Romo1 PF10247.4 EKG11705.1 - 1.1e-25 89.5 9.6 1.5e-25 89.1 6.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 EKG11705.1 - 0.032 14.2 2.2 0.045 13.7 1.5 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EKG11705.1 - 0.11 12.1 1.1 0.27 10.8 0.8 1.6 1 0 0 1 1 1 0 Glycine zipper FHA PF00498.21 EKG11706.1 - 3.3e-16 59.1 0.0 1e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 FHA domain bZIP_1 PF00170.16 EKG11706.1 - 0.0033 17.3 1.4 0.0033 17.3 1.0 3.4 3 1 1 4 4 4 1 bZIP transcription factor UPF0278 PF08745.6 EKG11706.1 - 0.043 13.0 0.4 0.082 12.1 0.3 1.4 1 0 0 1 1 1 0 UPF0278 family RBD-FIP PF09457.5 EKG11706.1 - 0.54 10.1 4.4 9.1 6.1 0.3 2.8 2 0 0 2 2 2 0 FIP domain TBPIP PF07106.8 EKG11706.1 - 1.5 8.3 16.5 0.42 10.1 1.9 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EKG11706.1 - 1.9 8.0 23.3 2.3 7.8 1.4 3.2 3 0 0 3 3 3 0 Mnd1 family Prominin PF05478.6 EKG11706.1 - 8.3 3.7 6.0 2.2 5.6 0.7 2.0 2 0 0 2 2 2 0 Prominin Ank_2 PF12796.2 EKG11707.1 - 1.3e-48 163.2 0.1 4.6e-17 62.1 0.0 8.8 5 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EKG11707.1 - 3.6e-38 127.5 5.0 3.7e-06 26.4 0.0 11.2 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.1 EKG11707.1 - 3.2e-34 116.1 10.7 0.00042 20.4 0.1 12.2 12 1 1 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG11707.1 - 6.9e-33 109.3 0.9 0.00074 19.5 0.0 12.0 14 0 0 14 14 14 6 Ankyrin repeat Ank_4 PF13637.1 EKG11707.1 - 1.3e-29 102.0 5.3 6.3e-08 32.9 0.0 10.9 10 3 2 12 12 12 6 Ankyrin repeats (many copies) RRM_1 PF00076.17 EKG11708.1 - 6.6e-12 44.8 0.0 1.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG11708.1 - 1.1e-06 28.4 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.1 EKG11709.1 - 0.0023 17.8 0.0 0.86 9.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG11709.1 - 0.15 12.7 2.2 29 5.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIP PF00230.15 EKG11711.1 - 1.7e-46 158.5 21.7 2.1e-46 158.2 15.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein zf-RING_2 PF13639.1 EKG11712.1 - 9.9e-14 50.9 5.7 1.8e-13 50.0 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EKG11712.1 - 6.5e-11 41.8 0.0 1.4e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-rbx1 PF12678.2 EKG11712.1 - 2e-09 37.4 1.1 4.2e-09 36.3 0.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKG11712.1 - 2.2e-09 37.1 5.2 3.6e-09 36.5 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG11712.1 - 1.2e-08 34.4 3.1 1.8e-08 33.8 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG11712.1 - 4.3e-08 32.6 3.3 6.3e-08 32.1 2.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG11712.1 - 3e-07 30.0 2.4 4.6e-07 29.4 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKG11712.1 - 0.00037 20.2 0.6 0.0011 18.8 0.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EKG11712.1 - 0.083 12.9 3.7 0.2 11.7 2.6 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EKG11712.1 - 0.11 12.4 3.9 0.22 11.4 2.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EKG11712.1 - 0.12 12.0 2.6 0.26 11.0 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EKG11712.1 - 0.13 12.2 2.3 0.41 10.6 1.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EKG11712.1 - 1.1 8.9 2.5 1.9 8.1 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EKG11712.1 - 1.9 8.5 3.4 3.4 7.7 2.4 1.4 1 0 0 1 1 1 0 RING-like domain Sec2p PF06428.6 EKG11713.1 - 0.037 13.8 2.5 0.059 13.2 1.7 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF3552 PF12072.3 EKG11714.1 - 0.00072 18.8 9.2 0.00072 18.8 6.4 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) ATG16 PF08614.6 EKG11714.1 - 0.0077 16.0 5.3 0.0077 16.0 3.7 1.9 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.4 EKG11714.1 - 0.015 14.2 6.8 0.022 13.6 4.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GP20 PF06810.6 EKG11714.1 - 0.12 11.8 3.9 0.15 11.5 2.2 1.5 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF148 PF02520.12 EKG11714.1 - 0.68 9.7 7.9 0.25 11.1 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF148 ADIP PF11559.3 EKG11714.1 - 3 7.7 14.0 8.7 6.2 9.7 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EKG11714.1 - 9.9 6.1 13.3 1 9.3 5.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Macoilin PF09726.4 EKG11716.1 - 0.0076 14.5 0.6 0.0088 14.3 0.4 1.1 1 0 0 1 1 1 1 Transmembrane protein Jnk-SapK_ap_N PF09744.4 EKG11716.1 - 0.0093 15.9 4.0 0.017 15.1 2.8 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.3 EKG11716.1 - 0.02 14.6 3.3 0.032 13.9 2.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BicD PF09730.4 EKG11716.1 - 0.027 12.8 7.7 0.036 12.4 5.3 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D IncA PF04156.9 EKG11716.1 - 0.041 13.4 1.4 0.056 13.0 1.0 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EKG11716.1 - 0.13 10.1 0.4 0.15 9.8 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family L31 PF09784.4 EKG11716.1 - 0.15 12.1 1.0 0.3 11.1 0.7 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF972 PF06156.8 EKG11716.1 - 0.22 11.8 5.2 0.49 10.7 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Latarcin PF10279.4 EKG11716.1 - 1.6 8.9 11.9 4 7.7 2.9 2.5 1 1 1 2 2 2 0 Latarcin precursor HALZ PF02183.13 EKG11716.1 - 4.5 7.0 10.1 1.5 8.6 1.5 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.10 EKG11716.1 - 5.5 6.5 9.6 8.6 5.9 5.1 2.1 1 1 1 2 2 2 0 Septum formation initiator Sas10_Utp3 PF04000.10 EKG11717.1 - 2.1e-16 59.8 0.6 2.1e-16 59.8 0.4 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Hid1 PF12722.2 EKG11717.1 - 0.8 7.3 10.5 0.96 7.0 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF572 PF04502.8 EKG11717.1 - 2.1 7.4 25.1 2.8 7.0 17.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ApbA_C PF08546.6 EKG11718.1 - 8e-30 103.4 0.1 1.2e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EKG11718.1 - 9.4e-28 96.5 0.0 1.3e-26 92.8 0.0 2.2 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Lactonase PF10282.4 EKG11719.1 - 2.6e-81 273.4 0.0 4.2e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Hydrolase_6 PF13344.1 EKG11719.1 - 2.9e-21 75.2 0.0 7.6e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Peptidase_M20 PF01546.23 EKG11719.1 - 3.3e-19 69.1 0.3 5.8e-19 68.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Hydrolase_like PF13242.1 EKG11719.1 - 4.5e-17 61.5 0.0 1.6e-16 59.7 0.0 2.1 1 0 0 1 1 1 1 HAD-hyrolase-like M20_dimer PF07687.9 EKG11719.1 - 3.5e-12 46.0 0.6 7.6e-12 44.9 0.1 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain zf-His_Me_endon PF05551.6 EKG11720.1 - 2.6e-11 43.6 0.7 2.6e-11 43.6 0.5 2.1 2 0 0 2 2 2 1 Zinc-binding loop region of homing endonuclease PFU PF09070.6 EKG11721.1 - 0.0034 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Pec_lyase_C PF00544.14 EKG11722.1 - 2.4e-25 89.1 0.3 4.5e-25 88.2 0.0 1.6 2 0 0 2 2 2 1 Pectate lyase Asp PF00026.18 EKG11723.1 - 2.5e-58 197.8 11.8 2.5e-58 197.8 8.2 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG11723.1 - 0.0007 20.0 0.2 0.0007 20.0 0.1 3.7 3 1 0 3 3 3 1 Aspartyl protease Ashwin PF15323.1 EKG11723.1 - 3.9 7.4 11.4 6 6.8 7.9 1.3 1 0 0 1 1 1 0 Developmental protein Ank_2 PF12796.2 EKG11726.1 - 9.8e-21 73.9 1.2 2.7e-09 37.2 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG11726.1 - 1.3e-10 41.5 5.0 0.00087 19.7 0.0 6.3 5 3 3 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.25 EKG11726.1 - 9.6e-10 37.7 10.7 0.096 12.5 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EKG11726.1 - 9e-08 32.1 7.6 0.025 14.8 0.0 5.8 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG11726.1 - 4.3e-07 29.5 7.5 0.24 11.7 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat DctQ PF04290.7 EKG11727.1 - 0.086 12.5 1.9 12 5.7 0.5 2.9 2 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Bac_rhamnosid PF05592.6 EKG11728.1 - 2.7e-05 22.5 0.0 0.02 13.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase TGF_beta_GS PF08515.7 EKG11728.1 - 0.12 11.7 1.3 0.25 10.7 0.9 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Trehalase PF01204.13 EKG11729.1 - 0.0001 21.0 0.2 0.00012 20.8 0.1 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 EKG11729.1 - 0.016 13.9 1.2 0.017 13.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Ank_2 PF12796.2 EKG11730.1 - 9.2e-05 22.7 0.0 0.0022 18.2 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG11730.1 - 0.086 13.1 0.0 0.3 11.3 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) IL1_propep PF02394.11 EKG11731.1 - 0.00097 19.5 1.9 0.0028 18.0 1.3 1.8 1 0 0 1 1 1 1 Interleukin-1 propeptide Glyco_hydro_20 PF00728.17 EKG11733.1 - 1.1e-20 74.1 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EKG11733.1 - 8.3e-07 29.5 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WG_beta_rep PF14903.1 EKG11733.1 - 0.17 12.1 0.0 11 6.4 0.0 2.4 2 0 0 2 2 2 0 WG containing repeat FAD_binding_4 PF01565.18 EKG11735.1 - 4.6e-18 65.0 1.7 1.2e-17 63.7 1.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG11735.1 - 4.4e-09 36.1 0.5 8.4e-09 35.1 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.2 EKG11736.1 - 1.7e-07 30.8 1.0 3.6e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EKG11736.1 - 0.001 18.6 8.2 0.048 13.3 1.3 5.3 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG11736.1 - 0.0048 16.6 4.4 0.25 11.1 0.4 4.2 3 2 1 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 EKG11736.1 - 0.25 11.5 4.0 33 4.9 0.1 5.1 6 0 0 6 6 6 0 Leucine Rich repeat Rsm22 PF09243.5 EKG11738.1 - 1.3e-30 106.3 0.0 1.2e-15 57.3 0.0 3.3 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Pkinase PF00069.20 EKG11739.1 - 1.6e-38 132.3 0.0 2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG11739.1 - 8.9e-14 51.1 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG11739.1 - 1.7e-05 24.7 0.0 0.0015 18.3 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EKG11739.1 - 0.055 12.2 0.1 0.083 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DASH_Spc19 PF08287.6 EKG11740.1 - 6.8e-50 168.6 4.2 9.1e-50 168.2 2.9 1.2 1 0 0 1 1 1 1 Spc19 UPF0184 PF03670.8 EKG11740.1 - 0.037 14.1 0.1 0.084 13.0 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) RP-C_C PF11800.3 EKG11740.1 - 0.092 12.4 2.6 0.12 12.0 1.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Prominin PF05478.6 EKG11740.1 - 0.17 9.3 0.6 0.35 8.3 0.0 1.6 2 0 0 2 2 2 0 Prominin COG2 PF06148.6 EKG11740.1 - 0.24 11.2 4.9 0.088 12.6 0.5 2.3 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlgN PF05130.7 EKG11740.1 - 0.4 10.9 7.0 0.7 10.1 4.5 1.7 1 1 0 1 1 1 0 FlgN protein COG5 PF10392.4 EKG11740.1 - 0.52 10.2 5.3 5.8 6.8 0.1 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 HSP70 PF00012.15 EKG11742.1 - 6.6e-77 258.8 3.8 1e-76 258.1 2.6 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKG11742.1 - 2.7e-10 39.3 1.5 4.2e-10 38.7 1.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EKG11742.1 - 0.0019 17.1 1.1 0.017 14.0 0.6 2.4 1 1 1 2 2 2 1 Type IV pilus assembly protein PilM; Kelch_3 PF13415.1 EKG11744.1 - 7.5e-32 108.7 17.6 2.8e-07 30.4 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EKG11744.1 - 1.3e-30 104.9 8.7 1e-07 31.6 0.5 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EKG11744.1 - 1.5e-27 95.0 2.3 9.3e-08 31.8 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EKG11744.1 - 2e-27 94.4 0.3 2e-09 36.8 0.2 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 EKG11744.1 - 1.3e-24 85.2 2.1 1.2e-07 31.5 0.3 5.6 5 0 0 5 5 5 5 Kelch motif Kelch_2 PF07646.10 EKG11744.1 - 4.5e-19 67.3 2.5 4.7e-08 32.4 0.2 5.2 5 0 0 5 5 5 4 Kelch motif RAG2 PF03089.9 EKG11744.1 - 0.049 12.3 0.0 2.1 6.9 0.0 2.9 3 0 0 3 3 3 0 Recombination activating protein 2 Vac_Fusion PF02346.11 EKG11744.1 - 4.9 6.6 6.9 23 4.5 0.3 3.8 4 0 0 4 4 4 0 Chordopoxvirus fusion protein Raptor_N PF14538.1 EKG11745.1 - 1.6e-68 229.3 0.1 3.7e-68 228.2 0.0 1.7 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EKG11745.1 - 1.2e-11 44.0 0.8 0.11 12.4 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKG11745.1 - 0.00026 20.7 1.9 0.0063 16.2 0.2 2.8 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region tRNA-synt_2 PF00152.15 EKG11746.1 - 3.5e-74 249.5 0.0 4.5e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKG11746.1 - 0.0002 21.1 0.1 0.00035 20.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF946 PF06101.6 EKG11748.1 - 6.5e-11 40.9 5.1 7e-10 37.5 0.7 2.6 3 0 0 3 3 3 2 Plant protein of unknown function (DUF946) ERG4_ERG24 PF01222.12 EKG11749.1 - 2.1e-142 474.6 19.8 2.6e-142 474.3 13.7 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4_2 PF13923.1 EKG11749.1 - 2.7e-07 30.5 8.9 5.2e-07 29.5 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG11749.1 - 3.9e-07 29.6 6.7 6.6e-07 28.9 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG11749.1 - 9.4e-07 28.5 6.7 1.7e-06 27.7 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKG11749.1 - 2.2e-06 27.3 6.4 4e-06 26.4 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EKG11749.1 - 2.2e-06 27.1 8.4 4.1e-06 26.3 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKG11749.1 - 2.6e-05 23.9 5.6 0.00011 21.9 4.1 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EKG11749.1 - 0.0017 18.0 3.8 0.0017 18.0 2.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EKG11749.1 - 1.3 8.5 6.1 3 7.4 4.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger UCH PF00443.24 EKG11750.1 - 1.3e-45 155.6 0.0 2.5e-45 154.6 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG11750.1 - 6.7e-19 68.4 0.0 1.2e-17 64.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Trehalase PF01204.13 EKG11750.1 - 0.21 10.1 0.0 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Trehalase NIPSNAP PF07978.8 EKG11751.1 - 3.1e-38 129.8 0.3 8.6e-28 96.3 0.0 2.7 3 0 0 3 3 3 2 NIPSNAP Git3 PF11710.3 EKG11754.1 - 7.2e-21 74.6 8.2 7.2e-21 74.6 5.7 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EKG11754.1 - 1.1e-06 28.3 2.9 1.4e-06 27.9 0.3 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Peptidase_M36 PF02128.10 EKG11754.1 - 0.014 14.2 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) Arb2 PF09757.4 EKG11756.1 - 5.7e-17 61.7 0.0 1.5e-16 60.3 0.0 1.6 1 1 0 1 1 1 1 Arb2 domain Ribosomal_S14 PF00253.16 EKG11756.1 - 8.3e-15 53.9 0.7 2.2e-14 52.5 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e DUF4147 PF13660.1 EKG11756.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) PAPS_reduct PF01507.14 EKG11757.1 - 2.7e-43 147.7 0.1 4.5e-43 147.0 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.12 EKG11758.1 - 2.4e-88 295.0 0.1 3.7e-88 294.4 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EKG11758.1 - 1.2e-57 193.9 0.0 1.8e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EKG11758.1 - 1.2e-53 180.7 0.0 2.1e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain hEGF PF12661.2 EKG11760.1 - 0.0083 16.1 1.5 0.018 15.0 1.0 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF SGT1 PF07093.6 EKG11761.1 - 0.091 11.1 0.1 0.1 10.9 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein SET PF00856.23 EKG11762.1 - 0.00015 22.1 0.0 0.00017 21.9 0.0 1.1 1 0 0 1 1 1 1 SET domain Coq4 PF05019.8 EKG11763.1 - 8.8e-81 270.0 0.0 1e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 GyrI-like PF06445.10 EKG11763.1 - 0.048 13.6 0.1 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 GyrI-like small molecule binding domain dsDNA_bind PF01984.15 EKG11764.1 - 2.4e-33 114.3 10.6 2.8e-33 114.1 7.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Sec2p PF06428.6 EKG11765.1 - 5.8e-24 83.8 14.7 5.8e-24 83.8 10.2 3.0 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p GTP_EFTU_D3 PF03143.12 EKG11765.1 - 0.23 11.6 0.8 0.55 10.4 0.5 1.5 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain MCLC PF05934.6 EKG11765.1 - 0.35 9.0 5.8 0.86 7.8 4.0 1.7 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF4363 PF14276.1 EKG11765.1 - 0.38 10.4 6.2 0.69 9.6 2.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) Reo_sigmaC PF04582.7 EKG11765.1 - 2.3 7.2 7.0 1.3 8.1 1.6 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 EKG11765.1 - 2.8 7.9 7.2 4 7.4 0.8 3.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PEMT PF04191.8 EKG11767.1 - 0.00014 21.9 0.7 0.00061 19.8 0.4 2.2 1 1 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EKG11767.1 - 0.0016 17.7 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EKG11767.1 - 0.025 14.7 0.2 0.059 13.5 0.1 1.7 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Acyl_transf_3 PF01757.17 EKG11767.1 - 0.033 13.0 10.8 0.053 12.3 7.4 1.3 1 1 0 1 1 1 0 Acyltransferase family S1-P1_nuclease PF02265.11 EKG11768.1 - 8.3e-73 245.1 0.5 9.7e-73 244.8 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF637 PF04830.8 EKG11768.1 - 0.21 11.2 3.6 6.6 6.3 0.1 2.6 3 0 0 3 3 3 0 Possible hemagglutinin (DUF637) PMT PF02366.13 EKG11769.1 - 1.3e-74 250.6 14.6 2.6e-74 249.6 10.1 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EKG11769.1 - 4.5e-55 186.1 0.0 7.9e-55 185.3 0.0 1.4 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.3 EKG11770.1 - 4.7e-57 193.1 28.2 1.3e-56 191.6 19.5 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EKG11770.1 - 9.7e-36 121.2 2.7 7.5e-17 60.7 0.1 2.5 2 0 0 2 2 2 2 Surp module DUF2573 PF10835.3 EKG11770.1 - 0.017 15.1 2.4 0.022 14.8 0.7 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2573) Complex1_LYR_1 PF13232.1 EKG11771.1 - 2.4e-19 69.2 4.3 3.1e-19 68.9 3.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EKG11771.1 - 3.5e-19 68.3 3.6 4.5e-19 67.9 2.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EKG11771.1 - 0.0033 17.8 0.3 0.0041 17.5 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like OmpH PF03938.9 EKG11773.1 - 0.94 9.3 9.5 3.2 7.6 6.6 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RRN9 PF10680.4 EKG11773.1 - 1.9 8.2 4.6 3.3 7.5 0.8 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor CVNH PF08881.5 EKG11774.1 - 7.4e-27 93.6 0.7 2.2e-26 92.0 0.5 1.9 1 0 0 1 1 1 1 CVNH domain COG2 PF06148.6 EKG11774.1 - 0.00054 19.8 2.2 0.0042 16.9 0.0 2.8 2 2 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Methyltransf_2 PF00891.13 EKG11774.1 - 0.031 13.4 0.3 0.058 12.5 0.2 1.4 1 0 0 1 1 1 0 O-methyltransferase APG6 PF04111.7 EKG11774.1 - 0.065 12.2 18.3 0.16 10.9 4.5 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 EKG11774.1 - 0.16 11.6 9.6 0.072 12.7 1.1 2.9 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD CENP-F_leu_zip PF10473.4 EKG11774.1 - 0.31 10.9 19.5 0.2 11.5 2.8 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vac_Fusion PF02346.11 EKG11774.1 - 0.35 10.3 5.8 5.3 6.5 2.8 2.9 2 0 0 2 2 2 0 Chordopoxvirus fusion protein CDC37_N PF03234.9 EKG11774.1 - 0.64 10.3 11.2 0.79 10.0 6.7 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 EKG11774.1 - 1.1 9.0 11.5 0.18 11.6 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ApoLp-III PF07464.6 EKG11774.1 - 1.1 9.2 14.2 0.13 12.2 2.3 2.9 2 2 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Hira PF07569.6 EKG11774.1 - 1.9 7.6 7.6 0.75 8.9 1.1 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split AAA_13 PF13166.1 EKG11774.1 - 2.3 6.5 18.1 2.5 6.4 1.5 2.1 2 0 0 2 2 2 0 AAA domain DUF2951 PF11166.3 EKG11774.1 - 3.4 7.5 7.8 3.8 7.4 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) V_ATPase_I PF01496.14 EKG11774.1 - 3.5 5.3 11.3 0.41 8.4 2.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.1 EKG11774.1 - 3.5 6.8 14.8 0.12 11.6 2.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) p450 PF00067.17 EKG11776.1 - 6.5e-62 209.5 0.0 7.3e-62 209.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 EKG11777.1 - 3.4e-11 43.0 0.0 6.9e-07 28.9 0.0 2.7 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EKG11777.1 - 3.1e-07 29.8 0.0 5.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EKG11777.1 - 6.4e-07 29.7 0.2 2.1e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EKG11777.1 - 1.4e-06 27.6 0.1 2.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EKG11777.1 - 1.9e-06 28.0 0.1 3.7e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG11777.1 - 2.2e-05 23.3 0.0 0.00014 20.6 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG11777.1 - 0.00014 20.8 0.0 0.0037 16.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EKG11777.1 - 0.00016 20.6 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EKG11777.1 - 0.0033 17.4 0.1 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 EKG11777.1 - 0.012 15.7 0.0 0.041 13.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EKG11779.1 - 8.1e-121 403.7 20.9 2.3e-120 402.2 14.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11779.1 - 1.7e-22 79.6 34.4 2.7e-21 75.6 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LtrA PF06772.6 EKG11781.1 - 2.4e-09 36.5 13.1 2.4e-09 36.5 9.1 3.5 3 1 0 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) Reprolysin_2 PF13574.1 EKG11782.1 - 0.025 14.6 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EKG11782.1 - 0.056 13.3 0.0 0.17 11.7 0.0 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12 p450 PF00067.17 EKG11783.1 - 2.8e-84 283.2 0.0 3.4e-84 283.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.15 EKG11784.1 - 9.6e-61 205.6 0.0 1.3e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EKG11784.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) CAP59_mtransfer PF11735.3 EKG11785.1 - 6.1e-78 261.3 0.0 7.8e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NAD_binding_10 PF13460.1 EKG11786.1 - 1e-07 32.1 0.1 3.3e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 EKG11786.1 - 6.9e-07 28.0 0.0 1.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 HIM1 NmrA PF05368.8 EKG11786.1 - 3.2e-06 26.5 0.0 7.6e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EKG11786.1 - 0.026 14.8 0.0 0.057 13.7 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EKG11786.1 - 0.074 12.4 0.0 0.67 9.3 0.0 2.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG11786.1 - 0.11 11.3 0.0 5.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF1471 PF07338.8 EKG11786.1 - 0.14 11.8 0.8 0.31 10.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) ETX_MTX2 PF03318.8 EKG11787.1 - 0.0051 16.4 2.7 0.0051 16.4 1.9 1.8 2 0 0 2 2 2 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 MdcG PF10620.4 EKG11787.1 - 0.016 14.7 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG EthD PF07110.6 EKG11788.1 - 2.9e-21 76.1 0.4 3.7e-21 75.8 0.3 1.1 1 0 0 1 1 1 1 EthD domain p450 PF00067.17 EKG11789.1 - 8.6e-52 176.1 0.1 9.6e-52 176.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4629 PF15442.1 EKG11789.1 - 0.14 12.2 0.1 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) FAA_hydrolase PF01557.13 EKG11790.1 - 2.2e-57 194.0 0.0 2.6e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 EKG11791.1 - 4.5e-05 22.4 1.8 0.022 13.6 0.1 2.7 2 1 1 3 3 3 2 Fungal specific transcription factor domain Epimerase PF01370.16 EKG11792.1 - 0.037 13.4 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG11792.1 - 0.2 10.5 0.0 9 5.1 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Glyoxalase PF00903.20 EKG11793.1 - 4.2e-07 29.9 0.0 5.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EKG11793.1 - 0.00074 20.0 0.0 0.0015 19.1 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain Methyltransf_2 PF00891.13 EKG11794.1 - 1.4e-32 112.8 0.0 2.3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EKG11794.1 - 3.4e-05 23.5 0.3 8.5e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.15 EKG11794.1 - 0.17 12.0 0.4 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator Meth_synt_2 PF01717.13 EKG11795.1 - 3.2e-13 49.3 0.0 1.3e-11 44.1 0.0 2.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EKG11795.1 - 4.2e-05 22.9 0.0 0.003 16.8 0.0 2.6 2 1 1 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Aspzincin_M35 PF14521.1 EKG11797.1 - 0.0051 17.3 0.0 0.015 15.7 0.0 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase SelR PF01641.13 EKG11800.1 - 2.2e-51 172.7 0.0 2.8e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 EKG11800.1 - 0.013 15.2 0.4 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) GFA PF04828.9 EKG11800.1 - 0.038 13.9 0.4 1.6 8.7 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-Mss51 PF13824.1 EKG11800.1 - 0.054 13.3 2.2 0.6 10.0 0.3 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DZR PF12773.2 EKG11800.1 - 0.28 11.0 3.7 6.2 6.7 2.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon MFS_1 PF07690.11 EKG11801.1 - 9.4e-27 93.6 16.0 1.6e-26 92.9 11.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EKG11801.1 - 0.01 14.0 2.9 0.016 13.3 2.0 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 EKG11801.1 - 0.08 12.7 1.2 0.38 10.5 0.1 2.6 3 0 0 3 3 3 0 MFS_1 like family DUF2516 PF10724.4 EKG11804.1 - 0.85 9.6 9.9 0.23 11.4 0.2 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2516) OPT PF03169.10 EKG11805.1 - 2.9e-166 554.5 48.3 2.9e-166 554.5 33.4 1.9 2 0 0 2 2 2 2 OPT oligopeptide transporter protein CcmD PF04995.9 EKG11805.1 - 2.9 7.7 8.4 0.068 12.9 0.5 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DAO PF01266.19 EKG11806.1 - 4.3e-48 164.0 0.0 5e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG11806.1 - 3.3e-06 27.1 0.0 0.00066 19.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG11806.1 - 1.2e-05 25.2 0.0 4.3e-05 23.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG11806.1 - 0.0016 17.3 0.1 0.006 15.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EKG11806.1 - 0.0031 17.2 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EKG11806.1 - 0.0035 17.1 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 ThiF family FAD_binding_3 PF01494.14 EKG11806.1 - 0.0056 15.7 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EKG11806.1 - 0.0095 15.7 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EKG11806.1 - 0.012 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EKG11806.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EKG11806.1 - 0.013 14.1 0.0 3.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 EKG11806.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EKG11806.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EKG11806.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EKG11806.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase GIDA PF01134.17 EKG11806.1 - 0.13 11.0 0.0 7.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EKG11806.1 - 0.13 12.2 0.0 1.2 9.1 0.0 2.0 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Asparaginase_2 PF01112.13 EKG11807.1 - 7.8e-05 21.5 0.0 8.4e-05 21.4 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Tht1 PF04163.7 EKG11808.1 - 0.024 13.0 11.6 2.9 6.1 5.7 2.8 2 1 0 2 2 2 0 Tht1-like nuclear fusion protein FliM PF02154.10 EKG11808.1 - 0.083 12.5 0.6 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 Flagellar motor switch protein FliM Filo_glycop PF01611.11 EKG11808.1 - 0.25 10.0 3.9 0.14 10.9 0.5 2.0 2 1 0 2 2 2 0 Filovirus glycoprotein Lzipper-MIP1 PF14389.1 EKG11808.1 - 1.1 9.3 12.0 2.1 8.5 2.2 3.1 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Ribosomal_L6 PF00347.18 EKG11809.1 - 2.6e-22 79.1 0.0 2.4e-15 56.7 0.0 3.0 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.20 EKG11810.1 - 7.9e-54 182.7 0.7 1.3e-53 182.0 0.5 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.8 EKG11811.1 - 3.6e-33 114.1 4.5 9.8e-31 106.2 0.1 3.3 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EKG11811.1 - 1.1e-14 53.9 2.9 1.6e-14 53.5 0.3 2.3 2 1 0 2 2 2 1 Rsm1-like zf-3CxxC PF13695.1 EKG11813.1 - 0.066 13.4 2.8 0.076 13.2 2.0 1.2 1 0 0 1 1 1 0 Zinc-binding domain PAN_1 PF00024.21 EKG11814.1 - 4e-05 23.2 0.4 4e-05 23.2 0.3 3.1 3 0 0 3 3 3 1 PAN domain LAMTOR PF15454.1 EKG11815.1 - 2.3e-15 56.6 0.1 4.1e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Atx10homo_assoc PF09759.4 EKG11816.1 - 1.3e-32 111.5 0.0 2.8e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain TIMELESS PF04821.9 EKG11816.1 - 0.0022 17.3 0.3 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 Timeless protein HMG_box PF00505.14 EKG11816.1 - 0.0061 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box NAAA-beta PF15508.1 EKG11816.1 - 0.015 15.6 0.2 0.16 12.3 0.0 2.6 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase HMG_box_2 PF09011.5 EKG11816.1 - 0.096 13.0 0.1 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain DUF2046 PF09755.4 EKG11816.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) COX7C PF02935.11 EKG11817.1 - 0.16 11.7 0.5 0.24 11.2 0.3 1.3 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIc ARID PF01388.16 EKG11819.1 - 3.4e-20 71.7 0.1 8.5e-20 70.4 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain NAD_binding_8 PF13450.1 EKG11821.1 - 1.3e-08 34.6 0.1 3.4e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG11821.1 - 0.00011 22.3 0.1 0.00032 20.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG11821.1 - 0.00061 18.3 0.3 0.00091 17.7 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EKG11821.1 - 0.00064 18.9 0.6 0.00096 18.3 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG11821.1 - 0.011 14.6 0.1 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EKG11821.1 - 0.031 14.1 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG11821.1 - 0.036 13.1 0.1 0.071 12.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DJ-1_PfpI PF01965.19 EKG11824.1 - 4e-15 55.5 0.0 8.3e-15 54.5 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EKG11824.1 - 1.1e-05 24.7 0.0 2.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Serpentine_r_xa PF03383.10 EKG11825.1 - 0.075 12.7 3.8 0.11 12.2 2.0 1.6 1 1 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa Cyclase PF04199.8 EKG11826.1 - 1.6e-12 47.4 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Sugar_tr PF00083.19 EKG11827.1 - 2.2e-68 230.9 25.5 2.5e-68 230.6 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11827.1 - 3.2e-24 85.3 56.9 5.9e-21 74.5 23.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EKG11828.1 - 1.3e-29 103.2 2.8 1.3e-29 103.2 1.9 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11828.1 - 1.8e-29 103.2 0.2 2.1e-29 103.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG11828.1 - 6.3e-08 32.4 0.3 1e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EKG11828.1 - 0.00075 19.2 0.5 0.0012 18.5 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EKG11828.1 - 0.00095 18.6 0.5 0.0025 17.2 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EKG11828.1 - 0.0065 16.0 0.1 0.0092 15.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain NAD_Gly3P_dh_N PF01210.18 EKG11828.1 - 0.041 13.6 0.7 0.069 12.8 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3Beta_HSD PF01073.14 EKG11828.1 - 0.047 12.3 0.5 0.069 11.8 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UPF0146 PF03686.8 EKG11828.1 - 0.06 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) NAD_binding_10 PF13460.1 EKG11828.1 - 0.076 13.0 1.3 0.13 12.2 0.9 1.4 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_18 PF12847.2 EKG11828.1 - 0.1 13.1 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EKG11828.1 - 0.12 12.4 0.2 0.22 11.5 0.1 1.5 2 0 0 2 2 2 0 Methyltransferase domain Aldedh PF00171.17 EKG11829.1 - 2.7e-153 510.6 0.0 3.3e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EKG11829.1 - 0.2 10.8 0.0 0.76 8.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) DUF977 PF06163.6 EKG11831.1 - 0.019 14.7 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) adh_short PF00106.20 EKG11833.1 - 1.8e-34 119.0 2.8 2.9e-34 118.4 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG11833.1 - 4.4e-31 108.5 3.2 5.3e-31 108.2 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG11833.1 - 4.5e-14 52.5 3.1 6.8e-14 51.9 2.1 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EKG11833.1 - 0.0035 17.2 1.0 0.0067 16.2 0.7 1.6 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 EKG11833.1 - 0.0096 15.3 0.5 0.028 13.8 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG11833.1 - 0.013 15.3 1.8 0.026 14.3 0.6 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EKG11833.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Git3 PF11710.3 EKG11834.1 - 4.6e-16 58.9 6.2 6.3e-08 32.4 1.3 2.2 2 0 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EKG11834.1 - 3.7e-05 22.7 1.3 0.004 16.1 0.6 2.3 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3_C PF11970.3 EKG11834.1 - 0.0037 16.9 0.0 0.0037 16.9 0.0 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term FAA_hydrolase PF01557.13 EKG11835.1 - 1.1e-29 103.4 0.0 1.3e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GFO_IDH_MocA_C PF02894.12 EKG11836.1 - 0.095 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF290 PF01060.18 EKG11836.1 - 0.14 12.1 0.1 0.43 10.6 0.0 1.7 2 0 0 2 2 2 0 Transthyretin-like family TPT PF03151.11 EKG11837.1 - 2e-05 24.2 2.7 2e-05 24.2 1.9 1.9 1 1 1 2 2 2 1 Triose-phosphate Transporter family PepSY_TM_3 PF13706.1 EKG11837.1 - 0.0055 16.0 2.7 0.0055 16.0 1.9 2.6 2 0 0 2 2 2 1 PepSY-associated TM helix Cu-oxidase_3 PF07732.10 EKG11838.1 - 2e-40 137.1 12.0 6.9e-40 135.4 1.3 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG11838.1 - 1.1e-37 128.5 15.2 3.2e-32 110.9 0.1 3.9 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 EKG11838.1 - 4.7e-32 111.0 2.6 1.7e-31 109.2 0.3 2.4 2 0 0 2 2 2 1 Multicopper oxidase Chitin_bind_1 PF00187.14 EKG11838.1 - 2.6e-10 40.0 42.1 2.4e-05 24.2 8.6 3.0 2 0 0 2 2 2 2 Chitin recognition protein RNA_pol_A_CTD PF03118.10 EKG11839.1 - 0.15 11.5 0.1 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Peptidase_S10 PF00450.17 EKG11840.1 - 1.6e-95 320.7 0.7 1.8e-95 320.5 0.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase UCH_1 PF13423.1 EKG11841.1 - 1.5e-26 93.5 0.2 2.4e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EKG11841.1 - 1.8e-24 86.8 0.0 2.7e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EKG11841.1 - 7.7e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EKG11842.1 - 0.017 14.9 0.0 0.34 10.8 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Peptidase_M35 PF02102.10 EKG11843.1 - 4.6e-06 25.5 0.0 5.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family PEPCK_ATP PF01293.15 EKG11844.1 - 5.4e-218 724.1 0.0 6.4e-218 723.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EKG11844.1 - 0.016 15.4 0.0 4.5 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKG11844.1 - 0.037 13.8 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EKG11844.1 - 0.066 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC2_membrane PF01061.19 EKG11845.1 - 1.2e-88 295.7 58.0 7.2e-49 165.8 13.5 3.1 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EKG11845.1 - 2.2e-36 123.6 0.6 5.4e-29 99.8 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EKG11845.1 - 1.6e-35 122.4 0.0 6.8e-18 65.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EKG11845.1 - 3.6e-13 49.2 34.6 6.2e-08 32.0 9.5 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EKG11845.1 - 7.8e-08 32.2 0.1 2.6e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EKG11845.1 - 8.8e-07 28.5 0.1 0.0022 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EKG11845.1 - 1.6e-05 24.1 0.0 9.2e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EKG11845.1 - 6.4e-05 23.0 0.0 0.092 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EKG11845.1 - 0.00039 21.2 0.5 0.03 15.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EKG11845.1 - 0.00039 19.9 0.2 0.0012 18.3 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EKG11845.1 - 0.0011 18.4 0.2 0.05 13.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG11845.1 - 0.0013 18.7 2.2 0.0079 16.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EKG11845.1 - 0.0063 16.6 0.5 0.52 10.4 0.2 3.3 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EKG11845.1 - 0.0083 15.7 0.9 0.19 11.3 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EKG11845.1 - 0.012 15.2 0.5 0.42 10.4 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EKG11845.1 - 0.018 14.9 0.1 0.27 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EKG11845.1 - 0.018 15.3 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EKG11845.1 - 0.041 13.8 0.1 0.041 13.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EKG11845.1 - 0.048 13.1 0.0 7.2 6.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EKG11845.1 - 0.072 13.0 0.0 2.5 8.0 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase NACHT PF05729.7 EKG11845.1 - 0.11 12.1 0.8 0.44 10.1 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EKG11845.1 - 0.2 11.0 2.6 5.6 6.2 0.1 3.3 3 0 0 3 3 3 0 AAA-like domain PWWP PF00855.12 EKG11846.1 - 0.00011 22.2 0.3 0.00034 20.7 0.0 1.9 2 0 0 2 2 2 1 PWWP domain DUF4537 PF15057.1 EKG11846.1 - 0.00017 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EKG11846.1 - 0.024 14.2 0.2 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain Tudor-knot PF11717.3 EKG11846.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Filament PF00038.16 EKG11846.1 - 1 8.7 5.6 0.094 12.1 0.9 1.5 2 0 0 2 2 2 0 Intermediate filament protein PAP1 PF08601.5 EKG11847.1 - 2e-74 251.3 16.8 2e-74 251.3 11.7 2.4 1 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EKG11847.1 - 1.2e-08 34.8 9.1 2e-08 34.0 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG11847.1 - 0.017 14.9 12.5 0.039 13.7 8.4 1.8 1 1 0 1 1 1 0 Basic region leucine zipper MbeD_MobD PF04899.7 EKG11847.1 - 0.05 13.4 0.9 0.096 12.5 0.6 1.4 1 0 0 1 1 1 0 MbeD/MobD like Adeno_PIX PF03955.9 EKG11847.1 - 0.056 13.9 0.9 0.16 12.5 0.6 1.8 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 EKG11847.1 - 0.066 13.5 9.5 0.13 12.5 6.6 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor IncA PF04156.9 EKG11847.1 - 0.57 9.7 3.5 0.91 9.0 2.4 1.2 1 0 0 1 1 1 0 IncA protein SIR2 PF02146.12 EKG11848.1 - 3e-25 88.9 0.0 8e-25 87.5 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Peptidase_M24 PF00557.19 EKG11849.1 - 2.7e-52 177.3 0.0 5.1e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EKG11849.1 - 1e-36 125.2 0.0 1.8e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Creatinase_N PF01321.13 EKG11849.1 - 0.065 13.7 0.0 0.26 11.7 0.0 2.1 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain LigB PF02900.13 EKG11850.1 - 1.2e-26 93.3 0.0 1.4e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3485 PF11984.3 EKG11851.1 - 0.019 14.0 0.2 0.022 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) Aldedh PF00171.17 EKG11852.1 - 5.2e-12 44.8 0.5 2.4e-10 39.3 0.4 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EKG11852.1 - 0.022 13.4 0.0 0.05 12.3 0.0 1.5 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) PepX_C PF08530.5 EKG11854.1 - 3.5e-41 141.4 0.6 5.3e-41 140.9 0.4 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EKG11854.1 - 2.7e-25 89.3 0.1 3.5e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EKG11854.1 - 0.035 13.9 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family NmrA PF05368.8 EKG11856.1 - 0.0093 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family DXP_redisom_C PF08436.7 EKG11856.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal But2 PF09792.4 EKG11858.1 - 4.5e-18 65.3 1.5 6.7e-18 64.8 1.1 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Tme5_EGF_like PF09064.5 EKG11859.1 - 0.23 11.1 1.4 0.5 10.0 1.0 1.5 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like adh_short_C2 PF13561.1 EKG11860.1 - 8.7e-26 91.1 0.0 1e-25 90.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG11860.1 - 1.7e-24 86.5 2.1 2.3e-24 86.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG11860.1 - 1.5e-13 50.8 0.5 1.8e-13 50.5 0.3 1.1 1 0 0 1 1 1 1 KR domain DUF1447 PF07288.6 EKG11860.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) Dfp1_Him1_M PF08630.5 EKG11861.1 - 5.6e-41 139.2 0.0 1.5e-40 137.8 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EKG11861.1 - 2.9e-23 81.2 0.1 5e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.2 EKG11861.1 - 0.00022 20.9 0.0 0.00052 19.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKG11861.1 - 0.0077 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pantoate_transf PF02548.10 EKG11862.1 - 3e-68 229.7 0.2 3.4e-68 229.5 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase UQ_con PF00179.21 EKG11863.1 - 2.4e-33 114.5 0.0 3.3e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Rad4 PF03835.10 EKG11864.1 - 1.7e-31 108.5 0.0 4e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EKG11864.1 - 4.3e-27 93.6 0.0 8.2e-27 92.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EKG11864.1 - 9.7e-21 73.0 0.2 1.8e-20 72.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EKG11864.1 - 3.8e-16 59.1 0.1 3.8e-16 59.1 0.1 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EKG11864.1 - 0.0006 19.9 0.0 0.0031 17.7 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily Dzip-like_N PF13815.1 EKG11864.1 - 2.1 8.1 7.4 0.087 12.6 0.6 2.0 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal E1-E2_ATPase PF00122.15 EKG11865.1 - 3.7e-42 143.9 3.9 1e-41 142.4 2.7 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKG11865.1 - 9.4e-27 94.8 0.0 1.7e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG11865.1 - 3.4e-11 43.6 0.0 8.1e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EKG11865.1 - 1e-09 38.3 0.0 2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EKG11865.1 - 1.4e-05 24.8 0.2 0.0021 17.6 0.1 2.6 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF2708 PF10917.3 EKG11870.1 - 0.14 11.9 2.5 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2708) Sugar_tr PF00083.19 EKG11871.1 - 3e-132 441.4 27.8 3.4e-132 441.2 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11871.1 - 4.6e-23 81.5 53.9 2.8e-20 72.3 19.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3433 PF11915.3 EKG11872.1 - 4.5e-19 68.4 0.1 1.1e-18 67.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) ADH_N_assoc PF13823.1 EKG11873.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Glyoxal_oxid_N PF07250.6 EKG11874.1 - 2.2e-40 138.2 0.0 1.5e-39 135.5 0.0 2.2 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EKG11874.1 - 3.6e-23 81.4 1.0 7.8e-23 80.4 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EKG11874.1 - 2.1e-16 59.5 93.5 2.3e-07 30.6 13.5 4.2 4 0 0 4 4 4 3 Chitin recognition protein Pkinase PF00069.20 EKG11876.1 - 0.054 12.6 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain G-patch PF01585.18 EKG11877.1 - 1.6e-11 43.8 1.3 4.2e-11 42.4 0.8 1.8 2 0 0 2 2 2 1 G-patch domain RRM_6 PF14259.1 EKG11877.1 - 0.0063 16.4 0.0 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EKG11877.1 - 0.014 15.2 2.7 0.015 15.1 0.2 2.3 2 0 0 2 2 2 0 DExH-box splicing factor binding site RRM_1 PF00076.17 EKG11877.1 - 0.07 12.7 0.1 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.13 EKG11878.1 - 1.5e-34 119.3 0.0 1.2e-10 40.9 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EKG11878.1 - 0.00065 19.2 0.1 0.023 14.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EKG11878.1 - 0.0068 16.8 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKG11878.1 - 0.025 14.5 0.0 0.057 13.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKG11878.1 - 0.064 13.0 0.2 0.78 9.5 0.0 2.5 3 0 0 3 3 3 0 Dynamin family RAP1 PF07218.6 EKG11878.1 - 0.21 9.6 2.9 0.32 9.0 2.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Nop14 PF04147.7 EKG11878.1 - 3 5.6 13.7 4.4 5.0 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family Radical_SAM PF04055.16 EKG11879.1 - 0.00012 22.3 0.0 0.00021 21.4 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily Mur_ligase_C PF02875.16 EKG11879.1 - 0.093 12.7 0.0 0.83 9.7 0.0 2.1 1 1 0 1 1 1 0 Mur ligase family, glutamate ligase domain Adaptin_N PF01602.15 EKG11881.1 - 8.5e-116 387.3 0.3 1.2e-115 386.8 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EKG11881.1 - 1.5e-57 193.6 0.6 3.1e-57 192.6 0.4 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EKG11881.1 - 3.4e-16 59.2 4.4 1.4e-05 25.2 0.1 6.5 2 2 5 7 7 7 4 HEAT repeats HEAT_PBS PF03130.11 EKG11881.1 - 0.0087 16.4 1.5 8.3 7.2 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HEAT PF02985.17 EKG11881.1 - 0.027 14.5 9.7 0.66 10.2 0.3 5.7 5 0 0 5 5 5 0 HEAT repeat DUF3730 PF12530.3 EKG11881.1 - 0.042 13.7 0.6 0.5 10.2 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) HEAT_EZ PF13513.1 EKG11881.1 - 0.067 13.6 4.9 0.14 12.6 0.7 3.4 3 0 0 3 3 3 0 HEAT-like repeat Phosducin PF02114.11 EKG11882.1 - 6.9e-10 38.0 0.0 1.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.16 EKG11884.1 - 9.1e-06 25.5 7.9 1.9e-05 24.5 5.5 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG11884.1 - 0.017 14.9 1.6 0.017 14.9 1.1 1.7 1 1 0 1 1 1 0 Basic region leucine zipper PAP1 PF08601.5 EKG11884.1 - 0.021 14.5 0.2 0.4 10.3 0.0 2.2 2 1 0 2 2 2 0 Transcription factor PAP1 HeH PF12949.2 EKG11884.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain bZIP_Maf PF03131.12 EKG11884.1 - 0.46 10.8 6.6 0.85 9.9 4.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF904 PF06005.7 EKG11884.1 - 1 9.6 4.3 0.32 11.2 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Acyltransferase PF01553.16 EKG11885.1 - 2.3e-12 46.4 0.0 3.4e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase NDUFB10 PF10249.4 EKG11887.1 - 7.7e-05 22.8 0.1 9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EKG11887.1 - 0.023 15.1 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase 3Beta_HSD PF01073.14 EKG11888.1 - 1.8e-69 233.5 0.0 2.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKG11888.1 - 2.7e-29 102.2 0.0 3.5e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG11888.1 - 5.1e-20 71.4 0.0 1.7e-18 66.4 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EKG11888.1 - 2.1e-13 50.6 0.0 3.7e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EKG11888.1 - 2e-09 36.7 0.0 2.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EKG11888.1 - 8.1e-09 35.6 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EKG11888.1 - 2.9e-07 29.6 0.0 6.5e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EKG11888.1 - 3.8e-06 26.6 0.0 4.5e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EKG11888.1 - 1.6e-05 24.2 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Pkinase PF00069.20 EKG11889.1 - 2.8e-67 226.6 0.0 4e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG11889.1 - 7.7e-38 130.0 0.0 1.1e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKG11889.1 - 2.5e-11 43.5 0.0 9.9e-08 31.9 0.0 2.7 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 EKG11889.1 - 0.00031 19.7 0.0 0.00063 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG11889.1 - 0.0024 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG11889.1 - 0.12 12.0 0.0 1.2 8.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M28 PF04389.12 EKG11890.1 - 1.4e-28 99.8 0.4 2.5e-28 99.0 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EKG11890.1 - 0.00021 20.8 0.0 0.0004 19.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Toxin_59 PF15537.1 EKG11890.1 - 0.039 14.0 0.2 0.29 11.2 0.0 2.4 2 1 1 3 3 3 0 Putative toxin 59 Cmc1 PF08583.5 EKG11891.1 - 4e-20 71.3 7.3 4.5e-20 71.1 5.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like EIN3 PF04873.8 EKG11891.1 - 0.013 14.8 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Ethylene insensitive 3 Dynactin_p22 PF07426.6 EKG11891.1 - 0.032 13.5 0.5 0.037 13.3 0.4 1.0 1 0 0 1 1 1 0 Dynactin subunit p22 CtIP_N PF10482.4 EKG11891.1 - 0.038 13.7 0.4 0.052 13.3 0.3 1.2 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF4047 PF13256.1 EKG11891.1 - 0.11 12.4 0.6 0.12 12.3 0.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Prefoldin_2 PF01920.15 EKG11892.1 - 1.9e-26 91.8 10.0 2.6e-26 91.4 6.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit Tho2 PF11262.3 EKG11892.1 - 0.016 14.2 1.3 0.039 12.9 0.9 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Xpo1 PF08389.7 EKG11892.1 - 0.021 14.7 1.6 0.025 14.4 1.1 1.1 1 0 0 1 1 1 0 Exportin 1-like protein Dehyd-heme_bind PF09098.5 EKG11892.1 - 0.024 14.1 0.1 0.041 13.3 0.1 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding IncA PF04156.9 EKG11892.1 - 0.026 14.1 6.6 0.039 13.5 4.6 1.2 1 0 0 1 1 1 0 IncA protein DUF4093 PF13331.1 EKG11892.1 - 0.047 13.9 1.0 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4093) Prefoldin PF02996.12 EKG11892.1 - 0.049 13.2 7.1 2.2 7.9 4.2 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF4351 PF14261.1 EKG11892.1 - 0.076 12.8 0.5 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) p25-alpha PF05517.7 EKG11892.1 - 0.086 13.0 2.1 0.81 9.9 0.1 2.1 2 0 0 2 2 2 0 p25-alpha PEPcase_2 PF14010.1 EKG11892.1 - 0.086 11.1 1.5 0.19 10.0 0.8 1.7 1 1 1 2 2 2 0 Phosphoenolpyruvate carboxylase GAS PF13851.1 EKG11892.1 - 0.11 11.7 9.4 0.18 10.9 6.5 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2089 PF09862.4 EKG11892.1 - 0.11 12.3 2.7 0.28 10.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) V_ATPase_I PF01496.14 EKG11892.1 - 0.11 10.2 3.4 0.13 10.1 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSBP1 PF06825.7 EKG11892.1 - 0.11 12.0 1.3 1.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 PMC2NT PF08066.7 EKG11892.1 - 0.16 12.2 1.1 2 8.7 0.1 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF641 PF04859.7 EKG11892.1 - 0.22 11.2 4.3 0.27 10.9 0.2 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) THOC7 PF05615.8 EKG11892.1 - 0.33 11.2 9.1 0.36 11.0 1.7 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 SMAP PF15477.1 EKG11892.1 - 0.52 10.6 4.5 6.1 7.1 1.2 2.5 2 1 0 2 2 2 0 Small acidic protein family FliJ PF02050.11 EKG11892.1 - 0.56 10.2 10.9 2.4 8.2 3.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2205 PF10224.4 EKG11892.1 - 1.2 8.7 8.4 4.9 6.8 0.8 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CBFD_NFYB_HMF PF00808.18 EKG11893.1 - 5.5e-29 100.0 1.4 8.6e-29 99.4 0.9 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKG11893.1 - 2.8e-07 30.5 0.1 4.9e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EKG11893.1 - 0.00069 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EKG11893.1 - 0.0015 18.2 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EKG11893.1 - 0.049 13.9 0.1 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TauD PF02668.11 EKG11894.1 - 1e-53 182.6 0.0 1.7e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mito_carr PF00153.22 EKG11895.1 - 2.8e-67 222.4 2.6 2.2e-21 75.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ofd1_CTDD PF10637.4 EKG11896.1 - 9.6e-91 303.5 0.0 6.8e-86 287.6 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EKG11896.1 - 1.6e-15 57.4 0.0 3.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNase_H2-Ydr279 PF09468.5 EKG11896.1 - 1.9 7.6 6.7 0.44 9.7 1.5 2.0 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) RRM_1 PF00076.17 EKG11897.1 - 7e-41 137.7 0.0 6.9e-20 70.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG11897.1 - 4.5e-32 109.8 0.0 4.9e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG11897.1 - 1.4e-19 69.6 0.0 5.5e-09 35.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg6_Alg8 PF03155.10 EKG11898.1 - 8.6e-129 430.4 20.9 6.8e-82 275.7 7.1 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF4337 PF14235.1 EKG11898.1 - 0.4 10.5 0.8 0.7 9.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) COX17 PF05051.8 EKG11899.1 - 1e-21 76.6 5.8 1.3e-21 76.3 4.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 EKG11899.1 - 0.013 15.3 2.4 0.026 14.4 1.7 1.5 1 1 0 1 1 1 0 CHCH domain Cmc1 PF08583.5 EKG11899.1 - 0.023 14.4 5.8 0.084 12.6 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.1 EKG11900.1 - 7.1e-12 44.0 3.2 0.24 11.6 0.0 6.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 EKG11900.1 - 4.7e-09 35.6 5.1 0.0046 16.5 0.0 5.1 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EKG11900.1 - 5.9e-06 25.6 5.0 8.7 6.8 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 EKG11900.1 - 6e-05 22.6 1.8 3.8 8.1 0.0 5.3 5 0 0 5 5 5 1 Leucine rich repeat LRR_8 PF13855.1 EKG11900.1 - 0.0036 17.0 5.8 0.55 10.0 0.0 3.8 3 1 0 3 3 3 2 Leucine rich repeat Nucleoplasmin PF03066.10 EKG11900.1 - 0.54 9.7 14.4 0.98 8.9 10.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EKG11900.1 - 2.7 7.1 8.8 3.9 6.6 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Herpes_pp38 PF04846.8 EKG11901.1 - 0.029 13.6 0.1 0.074 12.3 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Beta_elim_lyase PF01212.16 EKG11902.1 - 1.5e-64 217.9 0.1 1.8e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EKG11902.1 - 0.00014 20.2 0.0 0.00021 19.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pec_lyase_C PF00544.14 EKG11903.1 - 2.7e-48 164.0 6.4 3.7e-48 163.6 4.4 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EKG11903.1 - 4.1e-07 29.8 12.7 3e-06 27.0 8.7 2.2 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 EKG11903.1 - 0.0009 18.4 8.4 0.031 13.4 5.9 2.1 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Sugar_tr PF00083.19 EKG11904.1 - 7.6e-63 212.6 7.0 1.2e-62 212.0 4.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG11904.1 - 4.2e-19 68.4 24.6 1.2e-18 66.9 17.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EKG11905.1 - 4.4e-25 88.0 1.9 7.3e-25 87.3 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DRMBL PF07522.9 EKG11907.1 - 1.7e-34 118.1 0.0 3.3e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EKG11907.1 - 9.6e-13 48.1 0.0 2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG11907.1 - 0.13 11.8 0.6 0.35 10.5 0.4 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Sugar_tr PF00083.19 EKG11908.1 - 5.4e-22 77.9 22.4 4.7e-21 74.9 15.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_transf_34 PF05637.7 EKG11910.1 - 3.7e-65 219.7 0.2 4.8e-65 219.3 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Herpes_US9 PF06072.6 EKG11911.1 - 0.017 14.9 1.4 0.035 13.9 1.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 PRKCSH PF07915.8 EKG11912.1 - 5.8e-20 71.8 0.6 2.5e-19 69.8 0.1 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EKG11912.1 - 0.018 14.5 0.0 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein DUF295 PF03478.13 EKG11912.1 - 0.12 11.8 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF295) HABP4_PAI-RBP1 PF04774.10 EKG11914.1 - 0.12 12.8 0.8 0.19 12.2 0.6 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Git3 PF11710.3 EKG11916.1 - 5.6e-19 68.5 10.5 1.5e-18 67.1 7.3 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EKG11916.1 - 1.3e-06 27.5 5.6 3.1e-05 23.0 1.4 2.2 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3_C PF11970.3 EKG11916.1 - 0.0048 16.6 6.7 0.0059 16.3 0.1 3.0 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term ERGIC_N PF13850.1 EKG11916.1 - 0.14 12.1 1.0 37 4.3 0.0 3.2 3 1 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) AAA PF00004.24 EKG11917.1 - 2.8e-47 160.2 0.0 7.5e-43 145.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EKG11917.1 - 7.2e-05 22.2 0.1 0.00075 18.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 EKG11917.1 - 0.00054 18.9 0.0 0.00093 18.1 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 EKG11917.1 - 0.00057 20.6 0.0 0.0041 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKG11917.1 - 0.00063 19.8 0.0 0.0078 16.3 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EKG11917.1 - 0.00079 19.4 0.2 0.02 14.8 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EKG11917.1 - 0.0012 17.9 0.0 0.0027 16.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EKG11917.1 - 0.0016 17.8 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EKG11917.1 - 0.0029 17.5 0.0 0.0068 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EKG11917.1 - 0.0045 16.7 0.0 0.022 14.5 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain RNA_helicase PF00910.17 EKG11917.1 - 0.0096 16.0 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EKG11917.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 EKG11917.1 - 0.017 14.8 0.0 0.055 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EKG11917.1 - 0.019 14.1 0.1 0.042 13.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EKG11917.1 - 0.027 13.5 0.0 0.079 12.0 0.0 1.7 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 EKG11917.1 - 0.07 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 EKG11917.1 - 0.088 12.6 0.2 0.43 10.4 0.0 2.3 3 0 0 3 3 1 0 AAA domain AAA_18 PF13238.1 EKG11917.1 - 0.2 11.9 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EKG11917.1 - 0.2 11.5 0.0 0.46 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 EKG11917.1 - 0.35 9.4 0.0 0.54 8.8 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Abhydro_lipase PF04083.11 EKG11918.1 - 8.9e-20 69.8 0.0 1.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EKG11918.1 - 5.1e-06 26.5 0.2 1.3e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG11918.1 - 0.0018 17.9 0.0 0.0035 16.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG11918.1 - 0.0035 17.0 0.0 0.0095 15.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family p450 PF00067.17 EKG11919.1 - 6.6e-52 176.5 0.0 7.5e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APG6 PF04111.7 EKG11921.1 - 1.8e-119 398.4 0.4 2.1e-119 398.2 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C4H2 PF10146.4 EKG11921.1 - 0.00018 21.6 6.8 0.00027 21.0 4.7 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein DUF2138 PF09909.4 EKG11921.1 - 0.019 13.1 0.7 0.026 12.6 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) DUF342 PF03961.8 EKG11921.1 - 0.12 10.7 2.1 0.16 10.3 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ERM PF00769.14 EKG11921.1 - 0.29 10.6 18.0 0.11 11.9 4.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 EKG11921.1 - 0.3 8.8 4.5 0.41 8.4 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 EKG11921.1 - 0.4 9.8 11.6 0.14 11.2 6.2 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4337 PF14235.1 EKG11921.1 - 0.45 10.3 9.7 0.8 9.5 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HlyD PF00529.15 EKG11921.1 - 0.58 9.4 8.8 0.85 8.8 6.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF4164 PF13747.1 EKG11921.1 - 5.8 7.1 18.1 3.4 7.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Scm3 PF10384.4 EKG11922.1 - 1.1e-18 66.4 0.4 1.1e-18 66.4 0.3 2.6 2 0 0 2 2 2 1 Centromere protein Scm3 Myb_DNA-binding PF00249.26 EKG11922.1 - 0.00021 21.2 0.0 0.00052 20.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain AATase PF07247.7 EKG11923.1 - 2.3e-19 69.2 0.0 5.3e-19 68.1 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EKG11923.1 - 0.00015 20.7 0.0 0.004 16.0 0.0 2.1 2 0 0 2 2 2 1 Condensation domain CsgG PF03783.9 EKG11923.1 - 0.25 10.3 0.1 0.4 9.7 0.1 1.2 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG Ferric_reduct PF01794.14 EKG11924.1 - 1.5e-18 67.0 13.0 1.5e-18 67.0 9.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EKG11924.1 - 3.1e-12 46.6 0.0 1.3e-11 44.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG11924.1 - 2.8e-09 36.7 0.0 5.6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EKG11924.1 - 0.014 15.9 0.3 0.14 12.7 0.2 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EKG11924.1 - 0.061 13.4 10.3 0.11 12.6 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) PALP PF00291.20 EKG11925.1 - 1.6e-31 109.7 0.1 6.6e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EKG11925.1 - 1.2e-09 38.5 0.0 4.5e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain MFS_1 PF07690.11 EKG11926.1 - 8.6e-47 159.5 48.0 3.1e-43 147.8 33.6 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG11926.1 - 4.7e-15 55.1 10.8 4.7e-15 55.1 7.5 3.7 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 EKG11926.1 - 1.2e-13 50.1 29.3 2.8e-13 48.9 20.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PDR_CDR PF06422.7 EKG11926.1 - 4.3 7.0 5.5 4.3 7.0 0.6 2.9 2 1 0 2 2 2 0 CDR ABC transporter Cupin_2 PF07883.6 EKG11928.1 - 7.4e-07 28.5 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EKG11928.1 - 0.0003 20.1 0.0 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) DEAD PF00270.24 EKG11930.1 - 2.5e-17 62.8 0.0 4.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EKG11930.1 - 1.4e-07 31.5 0.0 5e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKG11930.1 - 1.6e-06 27.9 0.1 3.3e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EKG11930.1 - 0.19 10.9 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NPP1 PF05630.6 EKG11931.1 - 1.3e-66 224.2 0.2 1.6e-66 224.0 0.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) MT0933_antitox PF14013.1 EKG11932.1 - 0.011 15.8 2.8 0.011 15.8 1.9 2.1 2 1 0 2 2 2 0 MT0933-like antitoxin protein p450 PF00067.17 EKG11933.1 - 1.5e-65 221.5 0.0 2.1e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EKG11934.1 - 4e-07 29.1 1.4 6.2e-07 28.5 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAG1 PF05454.6 EKG11936.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Syndecan PF01034.15 EKG11936.1 - 0.02 14.5 0.7 4.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Syndecan domain EphA2_TM PF14575.1 EKG11936.1 - 0.036 14.4 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 EKG11936.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.1 EKG11936.1 - 0.99 9.5 5.3 3.2 7.8 3.4 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Paramyxo_ncap PF00973.14 EKG11940.1 - 1.3 7.5 1.6 3.3 6.2 1.1 1.6 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SNARE PF05739.14 EKG11941.1 - 1.4e-17 63.1 1.5 1.4e-17 63.1 1.1 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EKG11941.1 - 1.8e-15 56.9 0.4 1.8e-15 56.9 0.2 3.3 2 2 1 3 3 3 1 Syntaxin Syntaxin-18_N PF10496.4 EKG11941.1 - 0.0012 18.6 0.5 0.0012 18.6 0.4 2.7 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 EKG11941.1 - 0.011 15.3 0.6 0.011 15.3 0.4 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain zf-C4H2 PF10146.4 EKG11941.1 - 0.021 14.8 4.1 0.21 11.5 0.0 2.6 2 1 0 2 2 2 0 Zinc finger-containing protein Siah-Interact_N PF09032.6 EKG11941.1 - 1.4 8.9 15.9 0.25 11.4 1.3 2.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal AAA_13 PF13166.1 EKG11941.1 - 3.1 6.1 12.3 1.3 7.3 5.8 1.9 2 0 0 2 2 2 0 AAA domain Allexi_40kDa PF05549.6 EKG11941.1 - 6.8 5.8 9.0 29 3.8 1.3 3.0 2 1 1 3 3 3 0 Allexivirus 40kDa protein p450 PF00067.17 EKG11942.1 - 1.4e-65 221.6 0.0 1.6e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like_2 PF13013.1 EKG11943.1 - 0.067 12.9 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain Peptidase_S15 PF02129.13 EKG11944.1 - 4.2e-38 131.3 6.2 2.9e-37 128.5 0.8 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EKG11944.1 - 6.7e-25 88.2 0.0 1.2e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EKG11944.1 - 5.6e-07 29.6 0.0 9.8e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG11944.1 - 0.038 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_5 PF12695.2 EKG11944.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA PF00004.24 EKG11945.1 - 8.3e-20 71.3 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG11945.1 - 0.0037 17.2 0.0 0.0095 15.9 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG11945.1 - 0.014 15.4 0.2 0.24 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EKG11945.1 - 0.018 14.7 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EKG11945.1 - 0.065 12.3 0.1 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 EKG11945.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EKG11945.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EKG11945.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AMP-binding PF00501.23 EKG11946.1 - 4.3e-17 61.6 0.1 5.5e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG11946.1 - 8.5e-15 55.4 0.0 1.5e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain COesterase PF00135.23 EKG11947.1 - 1.5e-46 159.2 0.9 1e-37 130.1 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG11947.1 - 4.3e-05 23.1 0.0 9.1e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG11947.1 - 0.045 13.5 0.1 0.076 12.7 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Melibiase PF02065.13 EKG11948.1 - 3e-48 164.4 0.0 1.5e-26 93.0 0.0 2.1 1 1 1 2 2 2 2 Melibiase Raffinose_syn PF05691.7 EKG11948.1 - 0.0021 15.6 0.0 0.003 15.1 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 FMN_bind_2 PF04299.7 EKG11949.1 - 3.1e-53 179.7 0.1 3.8e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.3 EKG11950.1 - 1.7e-10 40.0 0.0 3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 EKG11951.1 - 7.7e-10 39.1 0.0 2.7e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3273 PF11677.3 EKG11954.1 - 0.044 13.0 0.6 0.048 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) DUF2628 PF10947.3 EKG11956.1 - 0.0027 17.5 1.0 0.0027 17.5 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2628) YXWGXW PF12779.2 EKG11956.1 - 0.055 13.3 0.1 0.055 13.3 0.1 2.7 3 0 0 3 3 3 0 YXWGXW repeat (2 copies) DUF221 PF02714.10 EKG11957.1 - 1.2e-104 349.6 20.4 1.2e-104 349.6 14.2 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EKG11957.1 - 5.9e-38 129.9 0.9 5.9e-38 129.9 0.6 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EKG11957.1 - 1.5e-12 47.2 0.3 5.7e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EKG11957.1 - 0.013 16.0 1.1 0.013 16.0 0.7 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4463) DUF106 PF01956.11 EKG11957.1 - 0.82 9.1 12.0 2.8 7.4 0.0 4.5 4 0 0 4 4 4 0 Integral membrane protein DUF106 AA_permease_2 PF13520.1 EKG11958.1 - 4.9e-59 199.9 44.7 6e-59 199.6 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG11958.1 - 3.6e-19 68.4 32.8 4.8e-19 68.0 22.7 1.2 1 0 0 1 1 1 1 Amino acid permease SH3BGR PF04908.10 EKG11959.1 - 0.093 12.6 0.1 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein SUR7 PF06687.7 EKG11960.1 - 1.9e-34 119.0 4.3 2.3e-34 118.8 3.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EKG11960.1 - 0.00047 20.1 4.9 0.00047 20.1 3.4 2.1 2 1 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Integrase_1 PF12835.2 EKG11960.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Integrase NAP PF00956.13 EKG11962.1 - 0.0024 17.0 1.0 0.0032 16.6 0.7 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) AvrE PF11725.3 EKG11962.1 - 0.38 7.7 5.6 0.44 7.5 3.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor TSKS PF15358.1 EKG11966.1 - 0.013 13.6 0.0 0.018 13.2 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate GAF_3 PF13492.1 EKG11966.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 GAF domain HATPase_c PF02518.21 EKG11967.1 - 2.3e-22 78.8 0.0 3.9e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG11967.1 - 9.9e-18 64.1 0.3 3.2e-12 46.4 0.2 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c_3 PF13589.1 EKG11967.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IFRD PF05004.8 EKG11968.1 - 3.9e-30 104.9 0.9 5.5e-30 104.5 0.6 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.4 EKG11968.1 - 0.077 11.2 0.0 0.14 10.3 0.0 1.4 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit DUF469 PF04320.9 EKG11968.1 - 0.28 11.9 1.4 3 8.6 0.5 2.7 2 1 1 3 3 3 0 Protein with unknown function (DUF469) Corona_nucleoca PF00937.13 EKG11968.1 - 0.96 8.3 6.3 1.4 7.7 4.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Fungal_trans PF04082.13 EKG11969.1 - 7.1e-12 44.7 0.0 1.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EKG11969.1 - 7.4e-08 32.2 10.1 0.0012 19.0 2.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG11969.1 - 6.9e-07 29.1 11.1 0.00075 19.6 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG11969.1 - 0.069 13.4 5.0 0.57 10.5 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EKG11969.1 - 0.29 11.1 7.1 2.6 8.0 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG11969.1 - 2.3 8.4 4.3 2.6 8.2 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GTP_EFTU PF00009.22 EKG11970.1 - 7.7e-47 159.1 0.0 1.3e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EKG11970.1 - 2.8e-40 136.5 6.0 4.7e-40 135.8 4.2 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EKG11970.1 - 1.9e-18 66.0 0.0 3.7e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EKG11970.1 - 1.2e-05 24.7 0.0 3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EKG11970.1 - 4.5e-05 23.3 0.0 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EKG11970.1 - 5.2e-05 23.2 0.1 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EKG11970.1 - 0.0021 17.2 0.0 0.0055 15.9 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 EKG11970.1 - 0.027 14.3 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II HORMA PF02301.13 EKG11971.1 - 1.4e-46 158.6 0.0 1.4e-46 158.6 0.0 1.4 2 0 0 2 2 2 1 HORMA domain DUF1649 PF07855.7 EKG11971.1 - 0.0099 15.5 0.4 0.03 13.9 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1649) C2 PF00168.25 EKG11972.1 - 7.6e-13 48.1 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Rpr2 PF04032.11 EKG11973.1 - 0.066 13.0 0.2 0.066 13.0 0.1 3.1 4 0 0 4 4 4 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CCHC_5 PF14787.1 EKG11973.1 - 0.12 11.8 0.2 0.12 11.8 0.1 3.4 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger DUF35_N PF12172.3 EKG11973.1 - 0.24 11.3 7.7 0.95 9.4 0.0 4.4 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) tRNA-synt_1b PF00579.20 EKG11976.1 - 1.1e-22 80.5 0.0 2.1e-22 79.5 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PRELI PF04707.9 EKG11977.1 - 8.8e-21 74.0 0.1 5.2e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family TRI12 PF06609.8 EKG11979.1 - 6.2e-41 140.2 25.7 8.8e-41 139.7 17.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG11979.1 - 6.5e-23 81.0 55.2 9.6e-23 80.4 33.0 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG11979.1 - 1e-13 50.6 33.8 8.6e-11 41.0 7.3 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Recep_L_domain PF01030.19 EKG11979.1 - 0.0001 22.2 0.0 7.7 6.5 0.0 4.0 1 1 3 4 4 4 2 Receptor L domain ETRAMP PF09716.5 EKG11979.1 - 0.54 10.2 1.8 16 5.5 0.7 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) EPSP_synthase PF00275.15 EKG11980.1 - 2.5e-129 431.3 0.0 4.3e-129 430.5 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EKG11980.1 - 8.3e-103 342.8 0.1 1.9e-102 341.6 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EKG11980.1 - 5.9e-61 205.9 0.0 1e-60 205.1 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EKG11980.1 - 8.4e-38 129.7 0.0 2.5e-36 124.9 0.0 2.6 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.6 EKG11980.1 - 5.2e-21 74.5 0.0 1.2e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 EKG11980.1 - 4.4e-10 39.2 0.0 1.3e-09 37.7 0.0 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 EKG11980.1 - 1e-09 38.6 0.0 3e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EKG11980.1 - 0.00011 23.0 0.0 0.00053 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Ribosomal_S15 PF00312.17 EKG11983.1 - 9.8e-18 63.7 0.8 2.5e-17 62.3 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 SRA1 PF07304.6 EKG11983.1 - 0.044 13.5 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) Ribosomal_S2 PF00318.15 EKG11984.1 - 1.9e-43 148.1 0.0 6e-23 81.1 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 EAF PF09816.4 EKG11985.1 - 1.4e-15 57.1 0.9 2.5e-15 56.3 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor UQ_con PF00179.21 EKG11986.1 - 1e-19 70.3 0.4 2e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Dor1 PF04124.7 EKG11987.1 - 1.2e-51 175.1 0.0 4e-41 140.5 0.1 2.3 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 EKG11987.1 - 0.00017 21.3 0.5 0.00042 20.0 0.3 1.7 1 0 0 1 1 1 1 Vps51/Vps67 SLX9 PF15341.1 EKG11987.1 - 0.0026 18.1 0.8 0.007 16.8 0.1 2.1 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 RNA_pol_Rpb4 PF03874.11 EKG11988.1 - 7.4e-15 54.9 0.0 9.5e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Actin PF00022.14 EKG11990.1 - 2.3e-20 72.3 0.0 1.8e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Actin Nop PF01798.13 EKG11991.1 - 2.1e-54 182.8 1.4 1.3e-53 180.3 1.0 2.3 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EKG11991.1 - 1.2e-26 92.1 0.2 2.4e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EKG11991.1 - 3.9e-22 78.1 2.0 3.9e-22 78.1 1.4 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF760 PF05542.6 EKG11991.1 - 0.0099 16.0 0.1 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF760) CAF-1_p150 PF11600.3 EKG11991.1 - 0.14 11.5 39.2 0.28 10.5 27.2 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cpn60_TCP1 PF00118.19 EKG11994.1 - 6.5e-162 539.5 1.0 7.4e-162 539.3 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DJ-1_PfpI PF01965.19 EKG11995.1 - 1.5e-26 92.6 0.0 3e-26 91.6 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EKG11995.1 - 0.0038 16.7 0.0 0.012 15.0 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EKG11995.1 - 0.004 16.4 0.0 0.019 14.2 0.0 2.0 1 1 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EKG11995.1 - 0.029 13.9 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain p450 PF00067.17 EKG11997.1 - 5.4e-66 223.0 0.0 6.9e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EKG11999.1 - 7.5e-46 152.4 12.5 2.3e-07 30.4 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EKG11999.1 - 0.089 11.5 0.0 0.98 8.0 0.0 2.3 2 1 0 3 3 3 0 Nup133 N terminal like MBOAT PF03062.14 EKG12000.1 - 4.2e-18 65.5 13.7 1e-17 64.2 9.5 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EKG12000.1 - 9.6e-05 22.3 0.9 9.6e-05 22.3 0.6 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family ABC2_membrane_2 PF12679.2 EKG12000.1 - 0.012 14.4 0.0 0.012 14.4 0.0 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF2964 PF11177.3 EKG12000.1 - 0.039 13.8 0.1 0.19 11.6 0.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) PAP_assoc PF03828.14 EKG12001.1 - 2e-20 72.4 0.2 4.2e-20 71.4 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EKG12001.1 - 0.00028 21.1 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Isochorismatase PF00857.15 EKG12002.1 - 1.1e-28 100.3 0.1 1.4e-28 99.9 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family MAPEG PF01124.13 EKG12003.1 - 2.3e-18 66.0 3.5 2.9e-18 65.7 2.4 1.1 1 0 0 1 1 1 1 MAPEG family Pro_dh PF01619.13 EKG12004.1 - 2.8e-38 131.6 1.8 4e-38 131.1 1.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Ku PF02735.11 EKG12005.1 - 7.6e-40 136.4 0.0 1.3e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EKG12005.1 - 8.3e-33 113.6 0.0 1.2e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EKG12005.1 - 4.8e-12 46.2 0.0 1.5e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EKG12005.1 - 9.4e-08 31.3 0.0 2.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 SAP domain VWA_2 PF13519.1 EKG12005.1 - 0.0086 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain PUF PF00806.14 EKG12006.1 - 7.8e-23 78.6 0.0 7.4e-05 22.0 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EKG12006.1 - 4.4e-13 48.6 0.0 9.6e-13 47.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG12006.1 - 2.9e-09 36.6 0.0 6.4e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG12006.1 - 1.7e-08 34.3 0.0 3.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Phage_Mu_Gp45 PF06890.7 EKG12006.1 - 0.12 11.8 0.2 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein YL1 PF05764.8 EKG12007.1 - 2.8e-45 154.7 27.8 2.8e-45 154.7 19.2 2.1 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EKG12007.1 - 2.8e-10 39.5 0.1 4.6e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain YqeY PF09424.5 EKG12007.1 - 0.51 10.1 8.9 1.1 9.1 6.2 1.5 1 0 0 1 1 1 0 Yqey-like protein COesterase PF00135.23 EKG12008.1 - 5.2e-67 226.7 0.0 7e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG12008.1 - 1e-09 38.3 1.1 7.4e-09 35.4 0.7 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG12008.1 - 0.00064 18.9 0.1 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG12008.1 - 0.017 14.8 0.2 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Melibiase PF02065.13 EKG12009.1 - 6.1e-11 41.6 0.0 1.7e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 Melibiase MOSC PF03473.12 EKG12010.1 - 3.4e-20 71.8 0.0 9.5e-20 70.4 0.0 1.8 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EKG12010.1 - 1.7e-15 56.5 1.3 3.5e-15 55.5 0.9 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 EKG12010.1 - 2.4e-09 37.7 0.1 1.9e-08 34.8 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.9 EKG12010.1 - 1.3e-06 27.9 0.3 2.7e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 3-alpha domain NAD_binding_6 PF08030.7 EKG12010.1 - 0.00079 19.3 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Fer2_4 PF13510.1 EKG12010.1 - 0.0012 18.6 0.1 0.0062 16.3 0.0 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Glycos_transf_2 PF00535.21 EKG12011.1 - 4.5e-20 71.9 0.0 4.4e-11 42.7 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EKG12011.1 - 6.7e-06 26.0 0.0 0.0086 15.9 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Alpha-amylase PF00128.19 EKG12012.1 - 7.6e-10 38.6 0.0 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Ferrochelatase PF00762.14 EKG12013.1 - 3.8e-94 315.2 0.0 4.5e-94 314.9 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 EKG12014.1 - 1.6e-26 92.8 34.7 1.7e-25 89.4 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 EKG12014.1 - 0.12 10.8 4.2 0.79 8.1 1.4 2.3 1 1 1 2 2 2 0 Reduced folate carrier SepZ PF06066.6 EKG12015.1 - 0.29 11.1 5.5 0.2 11.6 1.9 1.8 2 0 0 2 2 2 0 SepZ TraT PF05818.7 EKG12015.1 - 0.84 9.0 2.8 1.1 8.6 1.9 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_OmpA PF13436.1 EKG12015.1 - 1 9.0 11.7 1.6 8.4 8.1 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain EST1_DNA_bind PF10373.4 EKG12016.1 - 6.6e-13 48.4 0.5 5e-12 45.6 0.1 2.2 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain AMP-binding PF00501.23 EKG12017.1 - 1.2e-25 89.8 0.1 1.6e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG12017.1 - 1.1e-05 26.2 0.0 2.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTS_EIIA_1 PF00358.15 EKG12017.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 MFS_1 PF07690.11 EKG12018.1 - 8.5e-39 133.2 32.4 8.5e-39 133.2 22.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12018.1 - 3.1e-11 42.5 3.6 3.1e-11 42.5 2.5 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DIOX_N PF14226.1 EKG12019.1 - 2.6e-22 79.5 0.0 7.4e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG12019.1 - 2.7e-13 50.0 0.0 4.6e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EKG12020.1 - 2.4e-27 95.6 36.7 3.1e-27 95.2 25.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG12020.1 - 0.00015 20.3 19.2 0.0021 16.5 2.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Tmemb_18A PF09771.4 EKG12020.1 - 0.093 12.7 0.0 0.57 10.1 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 188 Fungal_trans PF04082.13 EKG12022.1 - 4.2e-19 68.4 0.2 7.2e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG12022.1 - 6.7e-09 35.5 10.1 1.7e-08 34.2 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_trans_2_3 PF13632.1 EKG12023.1 - 2.5e-48 164.3 0.7 2.5e-48 164.3 0.5 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EKG12023.1 - 1e-07 31.7 0.3 1.8e-06 27.7 0.0 2.9 3 1 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EKG12023.1 - 9.1e-05 22.3 0.1 0.00027 20.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EKG12023.1 - 0.0029 16.9 0.0 0.0056 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 CagE_TrbE_VirB PF03135.9 EKG12023.1 - 0.058 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Glyco_hydro_16 PF00722.16 EKG12024.1 - 3.6e-21 75.2 2.1 5.8e-21 74.6 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sugar_tr PF00083.19 EKG12025.1 - 7.3e-64 215.9 14.1 9.1e-64 215.6 9.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG12025.1 - 4.5e-14 51.9 23.1 6e-14 51.5 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PhoD PF09423.5 EKG12026.1 - 1.4e-151 505.1 8.0 1.9e-151 504.7 5.5 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Iso_dh PF00180.15 EKG12027.1 - 4.6e-73 246.1 0.0 5.3e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BamHI PF02923.10 EKG12027.1 - 0.029 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BamHI DUF3991 PF13154.1 EKG12027.1 - 0.47 10.6 2.2 1.8 8.7 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3991) WD40 PF00400.27 EKG12028.1 - 2.3e-33 112.8 0.0 2e-09 36.9 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EKG12028.1 - 0.0002 21.1 0.0 1.1 8.8 0.0 2.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EKG12028.1 - 0.00077 18.9 0.4 0.016 14.6 0.1 2.1 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain DUF2158 PF09926.4 EKG12028.1 - 0.096 12.1 0.0 0.53 9.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) His_Phos_1 PF00300.17 EKG12029.1 - 5e-15 55.9 0.0 8.6e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LMWPc PF01451.16 EKG12032.1 - 5.3e-29 101.3 0.0 6.5e-28 97.7 0.0 1.9 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Chitin_synth_1 PF01644.12 EKG12033.1 - 4.7e-83 276.8 0.7 6.9e-83 276.3 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EKG12033.1 - 4e-31 106.5 0.0 7.1e-31 105.7 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EKG12033.1 - 1.4e-20 73.1 7.9 8.4e-17 60.7 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EKG12033.1 - 5.5e-09 36.1 0.0 2.8e-08 33.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EKG12033.1 - 5.5e-08 32.7 14.7 1e-06 28.6 10.2 2.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 adh_short PF00106.20 EKG12034.1 - 1.1e-18 67.6 6.9 1.3e-18 67.5 4.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG12034.1 - 1.3e-08 34.7 4.2 1.6e-08 34.4 2.9 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG12034.1 - 0.0012 18.6 0.1 0.0015 18.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EKG12034.1 - 0.0019 17.8 1.4 0.003 17.2 1.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EKG12034.1 - 0.085 12.0 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Clathrin PF00637.15 EKG12036.1 - 0.12 11.9 0.0 0.91 9.1 0.0 2.0 1 1 0 2 2 2 0 Region in Clathrin and VPS ApoO PF09769.4 EKG12037.1 - 5.4e-43 146.4 0.1 9.4e-42 142.3 0.0 2.2 2 0 0 2 2 2 1 Apolipoprotein O Peptidase_M3 PF01432.15 EKG12038.1 - 3.6e-128 428.4 0.0 6.8e-128 427.5 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 EKG12038.1 - 0.038 13.3 0.1 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Pkinase PF00069.20 EKG12039.1 - 1.6e-61 207.7 0.0 2.3e-61 207.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12039.1 - 4.2e-40 137.4 0.0 5.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG12039.1 - 2.5e-05 23.4 0.0 0.0001 21.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKG12039.1 - 0.0028 17.4 0.0 0.12 12.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKG12039.1 - 0.0096 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EKG12039.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EKG12039.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4281 PF14108.1 EKG12039.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) SH2_2 PF14633.1 EKG12040.1 - 4.5e-83 277.6 0.3 1.7e-82 275.7 0.0 2.2 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 EKG12040.1 - 5.7e-40 135.9 4.9 5.7e-40 135.9 3.4 4.3 5 0 0 5 5 5 1 Death-like domain of SPT6 YqgF PF14639.1 EKG12040.1 - 8.7e-35 119.5 0.0 2.4e-34 118.0 0.0 1.8 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 EKG12040.1 - 1.4e-31 108.6 0.0 2.7e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.1 EKG12040.1 - 4.7e-23 81.1 31.3 4.7e-23 81.1 21.7 5.4 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EKG12040.1 - 8.1e-20 71.0 0.3 2.7e-19 69.3 0.2 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EKG12040.1 - 8.5e-05 22.2 0.0 0.00032 20.4 0.0 2.1 1 0 0 1 1 1 1 SH2 domain S1 PF00575.18 EKG12040.1 - 0.0065 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain RasGAP PF00616.14 EKG12042.1 - 3.5e-47 160.6 0.0 1.4e-46 158.6 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EKG12042.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF3455 PF11937.3 EKG12043.1 - 1e-29 103.7 0.0 1.7e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Snf7 PF03357.16 EKG12045.1 - 4.8e-39 133.4 19.7 4.8e-39 133.4 13.7 2.0 2 0 0 2 2 2 1 Snf7 GDI PF00996.13 EKG12045.1 - 0.079 11.2 0.2 0.12 10.6 0.1 1.3 1 1 0 1 1 1 0 GDP dissociation inhibitor DUF3508 PF12018.3 EKG12045.1 - 0.12 11.3 10.4 2 7.3 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) A_deaminase_N PF08451.6 EKG12045.1 - 0.33 11.0 5.8 0.75 9.8 3.6 2.0 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Allexi_40kDa PF05549.6 EKG12045.1 - 0.73 9.0 7.4 0.98 8.6 5.0 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein MutS_III PF05192.13 EKG12045.1 - 0.86 9.3 5.7 1.2 8.8 4.0 1.3 1 1 0 1 1 1 0 MutS domain III DUF1664 PF07889.7 EKG12045.1 - 2.6 7.8 12.4 0.65 9.8 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4570 PF15134.1 EKG12045.1 - 7.7 6.4 12.1 2.3 8.1 5.8 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4570) Syntaxin-6_N PF09177.6 EKG12045.1 - 8.4 6.8 9.8 3.2 8.2 3.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ten1 PF12658.2 EKG12046.1 - 1.1e-31 109.1 0.0 1.3e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EKG12046.1 - 4.3e-07 29.5 0.0 9.7e-07 28.3 0.0 1.5 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit DUF2802 PF10975.3 EKG12047.1 - 0.034 13.8 0.2 0.047 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Ribosomal_L29 PF00831.18 EKG12047.1 - 0.055 13.1 0.9 0.075 12.7 0.6 1.2 1 0 0 1 1 1 0 Ribosomal L29 protein Matrilin_ccoil PF10393.4 EKG12047.1 - 0.094 12.0 0.6 0.16 11.3 0.4 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin TPR_11 PF13414.1 EKG12048.1 - 4.1e-24 84.0 5.5 2.9e-09 36.4 0.5 3.1 1 1 3 4 4 4 4 TPR repeat TPR_2 PF07719.12 EKG12048.1 - 3e-15 54.8 3.7 3.1e-05 23.5 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKG12048.1 - 9.7e-15 53.4 4.7 1.2e-06 27.8 0.1 4.7 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EKG12048.1 - 2.4e-12 46.6 0.5 2.5e-06 27.3 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG12048.1 - 6e-12 44.7 0.1 0.0031 17.5 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKG12048.1 - 3.9e-11 43.3 0.0 0.0016 19.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKG12048.1 - 6.8e-08 31.7 2.6 0.018 14.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG12048.1 - 1.9e-06 27.9 0.2 0.44 11.3 0.1 4.0 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG12048.1 - 2.8e-06 26.7 2.2 0.27 11.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG12048.1 - 8.7e-05 22.3 0.5 0.03 14.1 0.1 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG12048.1 - 0.00055 20.2 2.6 6.1 7.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG12048.1 - 0.00057 20.1 2.6 1.4 9.3 0.7 3.4 1 1 1 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG12048.1 - 0.00096 19.2 1.7 0.63 10.2 0.2 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 EKG12048.1 - 0.0013 17.9 2.2 0.41 9.9 0.2 2.5 2 0 0 2 2 2 2 SHNi-TPR Phage_CP76 PF06892.6 EKG12048.1 - 0.06 12.6 0.1 0.095 12.0 0.1 1.3 1 0 0 1 1 1 0 Phage regulatory protein CII (CP76) TPR_10 PF13374.1 EKG12048.1 - 0.21 11.5 1.5 6.7 6.7 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EKG12048.1 - 0.37 10.6 5.7 31 4.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKG12049.1 - 3.9e-27 93.6 14.9 6.1e-13 48.2 0.8 4.7 3 2 2 5 5 5 4 TPR repeat TPR_1 PF00515.23 EKG12049.1 - 6.7e-16 57.1 13.1 0.0031 17.0 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 EKG12049.1 - 8.9e-10 37.7 20.7 0.018 14.8 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EKG12049.1 - 1.3e-06 28.1 9.8 0.00026 20.8 0.5 3.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG12049.1 - 1.4e-06 27.9 3.6 4.6 7.6 0.1 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG12049.1 - 0.0012 19.4 21.1 0.87 10.3 1.2 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG12049.1 - 0.01 15.5 5.6 7.5 6.6 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Med3 PF11593.3 EKG12049.1 - 0.11 11.7 2.1 0.14 11.4 1.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_8 PF13181.1 EKG12049.1 - 0.21 11.4 3.8 24 5.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EKG12049.1 - 0.22 11.3 5.8 0.79 9.6 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EKG12049.1 - 2 7.7 6.9 32 3.8 0.2 4.2 4 0 0 4 4 4 0 SHNi-TPR Aminotran_4 PF01063.14 EKG12050.1 - 7.6e-10 38.6 0.0 1.1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV ADH_N PF08240.7 EKG12051.1 - 6.5e-26 90.2 0.7 1.2e-25 89.4 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG12051.1 - 3.8e-13 49.1 0.0 5.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG12051.1 - 0.12 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3602 PF12223.3 EKG12052.1 - 2.4e-17 63.1 8.4 2.7e-13 50.1 0.7 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Actin PF00022.14 EKG12053.1 - 6.8e-132 439.6 0.0 8.1e-132 439.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKG12053.1 - 0.0016 17.0 0.0 0.031 12.8 0.0 2.5 1 1 0 1 1 1 1 MreB/Mbl protein 2OG-FeII_Oxy_3 PF13640.1 EKG12054.1 - 6.3e-10 39.4 0.0 1.1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EKG12054.1 - 4.6e-06 26.1 0.1 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EKG12054.1 - 0.00024 21.3 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 EKG12055.1 - 4.7e-22 77.8 0.1 1.1e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EKG12055.1 - 1.1e-07 31.8 0.0 2.9e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Transthyretin PF00576.16 EKG12056.1 - 2.3e-27 95.1 0.1 1.1e-24 86.4 0.1 2.2 1 1 0 1 1 1 1 HIUase/Transthyretin family Aft1_HRA PF11786.3 EKG12057.1 - 1.6e-27 95.5 12.9 1.6e-27 95.5 8.9 2.5 1 1 1 2 2 2 1 Aft1 HRA domain bZIP_1 PF00170.16 EKG12057.1 - 3.1e-13 49.4 6.1 6.8e-13 48.3 4.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 EKG12057.1 - 1.2e-12 48.1 9.6 1.2e-12 48.1 6.7 5.4 4 3 1 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EKG12057.1 - 5.4e-06 26.1 6.5 5.4e-06 26.1 4.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EKG12057.1 - 0.0016 18.6 2.3 0.0016 18.6 1.6 2.7 2 0 0 2 2 2 1 bZIP Maf transcription factor Aft1_HRR PF11787.3 EKG12057.1 - 0.021 15.8 19.3 0.021 15.8 13.4 4.4 2 1 2 4 4 4 0 Aft1 HRR domain Macoilin PF09726.4 EKG12057.1 - 0.83 7.8 24.0 1.1 7.4 16.7 1.1 1 0 0 1 1 1 0 Transmembrane protein FYVE PF01363.16 EKG12058.1 - 0.00044 20.0 2.9 0.00044 20.0 2.0 2.8 3 0 0 3 3 3 1 FYVE zinc finger F-box-like PF12937.2 EKG12058.1 - 0.075 12.7 0.3 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 F-box-like Dus PF01207.12 EKG12059.1 - 1.5e-56 191.5 0.0 3.4e-56 190.3 0.0 1.6 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Glyco_hydro_35 PF01301.14 EKG12060.1 - 1.1e-82 277.9 1.7 1.5e-82 277.5 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EKG12060.1 - 1.1e-50 171.5 1.0 1.6e-50 170.9 0.7 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EKG12060.1 - 6.7e-33 113.2 2.4 5e-23 81.4 0.5 3.7 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EKG12060.1 - 1e-22 79.2 0.0 2.6e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EKG12060.1 - 1.3e-07 31.1 0.0 6e-06 25.6 0.0 2.7 1 1 1 2 2 2 2 Beta-galactosidase Cellulase PF00150.13 EKG12060.1 - 0.037 13.2 0.0 0.12 11.5 0.0 2.0 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Ank PF00023.25 EKG12061.1 - 2.4e-37 124.9 0.7 8.3e-08 31.6 0.0 5.7 5 1 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EKG12061.1 - 8.8e-35 118.9 0.0 7.3e-20 71.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG12061.1 - 1.1e-27 95.8 0.1 7.9e-13 48.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG12061.1 - 1.5e-26 89.7 1.0 1e-06 28.3 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EKG12061.1 - 3.6e-23 81.0 0.3 1.6e-07 31.3 0.0 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ribosomal_L3 PF00297.17 EKG12061.1 - 0.0064 15.9 0.2 0.0096 15.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 Glyco_hydro_3 PF00933.16 EKG12062.1 - 6.2e-51 173.1 0.0 9.2e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG12062.1 - 6.8e-44 150.0 0.1 1.2e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG12062.1 - 3.4e-26 90.9 0.1 6e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain p450 PF00067.17 EKG12063.1 - 5.7e-27 94.3 0.0 6.7e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EKG12065.1 - 1.5e-28 99.8 0.0 2.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG12065.1 - 4.3e-27 95.1 0.0 7.1e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase ParA PF10609.4 EKG12067.1 - 1.1e-34 118.1 0.0 1.9e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EKG12067.1 - 6e-16 58.4 0.0 9.4e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EKG12067.1 - 3.1e-07 30.4 0.0 1.7e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EKG12067.1 - 4.5e-06 25.9 0.9 4.7e-05 22.5 0.1 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 EKG12067.1 - 4.8e-05 23.0 0.0 0.094 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.6 EKG12067.1 - 9.2e-05 21.6 0.0 0.00016 20.8 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_19 PF13245.1 EKG12067.1 - 0.0029 17.3 0.4 0.035 13.8 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 EKG12067.1 - 0.004 16.3 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKG12067.1 - 0.0056 16.1 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EKG12067.1 - 0.026 13.9 0.0 0.077 12.4 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EKG12067.1 - 0.041 13.0 0.0 0.53 9.4 0.1 2.4 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 EKG12067.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EKG12067.1 - 0.077 12.5 0.2 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EKG12067.1 - 0.081 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG12067.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Zn_Tnp_IS1595 PF12760.2 EKG12067.1 - 0.11 12.3 0.1 0.32 10.8 0.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NB-ARC PF00931.17 EKG12067.1 - 0.11 11.3 0.1 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EKG12067.1 - 0.15 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EKG12067.1 - 0.18 11.9 0.1 0.51 10.5 0.1 1.7 1 1 0 1 1 1 0 RNA helicase ThiF PF00899.16 EKG12068.1 - 2.6e-52 176.2 0.0 3.2e-32 111.2 0.0 2.8 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EKG12068.1 - 8.7e-39 132.5 0.1 2.4e-38 131.1 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EKG12068.1 - 8.1e-37 124.6 1.8 3e-26 90.7 0.2 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EKG12068.1 - 7e-24 82.9 4.3 5.9e-21 73.5 0.8 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site F-box PF00646.28 EKG12069.1 - 3e-07 29.9 0.2 8.9e-07 28.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKG12069.1 - 4.4e-06 26.3 0.1 1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.6 EKG12069.1 - 0.03 14.7 0.2 0.055 13.8 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Amidase PF01425.16 EKG12072.1 - 1.1e-72 245.2 0.0 1.4e-72 244.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Nup84_Nup100 PF04121.8 EKG12074.1 - 8.7e-67 225.3 0.4 6.8e-53 179.4 0.0 2.6 1 1 0 2 2 2 2 Nuclear pore protein 84 / 107 DUF1903 PF08991.5 EKG12075.1 - 2e-24 85.4 11.4 2.4e-24 85.2 7.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) GCC2_GCC3 PF07699.8 EKG12075.1 - 0.03 13.9 0.5 0.03 13.9 0.4 2.0 2 1 0 2 2 2 0 GCC2 and GCC3 CHCH PF06747.8 EKG12075.1 - 0.03 14.2 7.3 0.03 14.2 5.1 1.7 2 0 0 2 2 2 0 CHCH domain Rad60-SLD PF11976.3 EKG12076.1 - 1.7e-22 78.8 0.1 2e-22 78.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EKG12076.1 - 2.3e-09 36.5 0.1 3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EKG12076.1 - 0.072 12.8 0.1 0.099 12.3 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) CoA_binding PF02629.14 EKG12077.1 - 2.6e-17 63.1 0.3 1.3e-16 60.9 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EKG12077.1 - 5.9e-16 58.4 0.4 9.5e-16 57.7 0.0 1.5 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 EKG12077.1 - 1.9e-07 30.7 0.0 3.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EKG12077.1 - 0.029 14.5 0.1 0.23 11.6 0.0 2.3 2 1 0 2 2 2 0 CoA binding domain FAM176 PF14851.1 EKG12078.1 - 3.3 7.3 6.3 1.6 8.3 0.1 2.1 2 0 0 2 2 2 0 FAM176 family DUF3043 PF11241.3 EKG12078.1 - 5.6 6.5 10.0 8.1 5.9 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FAD_binding_3 PF01494.14 EKG12079.1 - 4.1e-20 72.1 1.7 5.3e-18 65.1 1.2 2.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG12079.1 - 0.00044 19.1 0.0 0.017 13.9 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EKG12079.1 - 0.00073 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG12079.1 - 0.0041 17.0 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EKG12079.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 EKG12079.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EKG12079.1 - 0.029 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EKG12079.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 EKG12079.1 - 0.067 12.0 0.0 0.48 9.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG12079.1 - 0.092 11.1 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein PCI PF01399.22 EKG12080.1 - 2.3e-08 34.2 0.1 8.9e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain NAD_binding_10 PF13460.1 EKG12081.1 - 1.2e-19 71.0 0.0 1.7e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG12081.1 - 2.8e-16 59.4 0.0 3.5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EKG12081.1 - 8.8e-16 58.0 0.2 1.9e-15 56.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG12081.1 - 2.9e-12 45.8 0.1 5.1e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EKG12081.1 - 7.3e-11 41.4 0.0 2.2e-09 36.6 0.0 2.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EKG12081.1 - 4.1e-07 29.1 0.9 3.8e-05 22.7 0.6 2.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EKG12081.1 - 8.4e-05 22.5 0.0 0.00097 19.0 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EKG12081.1 - 0.00099 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EKG12081.1 - 0.0025 17.5 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 KR domain DDE_Tnp_1_3 PF13612.1 EKG12081.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.6 2 0 0 2 2 2 0 Transposase DDE domain HIM1 PF08732.5 EKG12081.1 - 0.021 13.3 0.0 0.031 12.7 0.0 1.2 1 0 0 1 1 1 0 HIM1 Polysacc_synt_2 PF02719.10 EKG12081.1 - 0.031 13.1 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UCH PF00443.24 EKG12082.1 - 3.6e-60 203.3 0.0 4.2e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG12082.1 - 3.3e-33 115.3 0.0 4.8e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.5 EKG12082.1 - 9.2 6.3 7.0 4.3 7.3 0.0 3.0 3 0 0 3 3 3 0 Zinc ribbon domain Exo_endo_phos PF03372.18 EKG12083.1 - 5.7e-23 82.1 0.1 5.7e-23 82.1 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 EKG12083.1 - 8.9e-11 41.3 6.4 4.6e-09 35.8 3.4 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EKG12083.1 - 5.1e-10 38.7 10.8 8.5e-06 25.2 0.8 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EKG12083.1 - 2.1e-05 23.9 9.5 0.49 10.6 0.2 5.0 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EKG12083.1 - 0.00081 19.2 13.6 0.46 10.9 0.6 4.3 4 0 0 4 4 4 3 Leucine rich repeat Methyltransf_25 PF13649.1 EKG12084.1 - 7.1e-10 39.1 0.0 1.2e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG12084.1 - 9.4e-10 38.2 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG12084.1 - 7.6e-09 35.9 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG12084.1 - 1e-06 28.5 0.0 2.5e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG12084.1 - 8.2e-06 25.8 0.0 2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG12084.1 - 4e-05 22.8 0.0 6.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EKG12084.1 - 4.1e-05 23.9 0.0 6.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG12084.1 - 0.00011 22.7 0.0 0.00019 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EKG12084.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EKG12084.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Complex1_LYR_2 PF13233.1 EKG12085.1 - 7.5e-09 36.0 0.3 9.1e-09 35.7 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like 4HBT_2 PF13279.1 EKG12086.1 - 3.2e-09 37.2 0.1 4.3e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily ECH PF00378.15 EKG12088.1 - 4.5e-51 173.3 0.1 5.7e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Acetyltransf_13 PF13880.1 EKG12089.1 - 7.9e-21 73.5 0.1 1.7e-20 72.5 0.1 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EKG12089.1 - 1.7e-13 49.8 0.0 3.4e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EKG12089.1 - 3.6e-05 23.7 0.0 9.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FRG PF08867.6 EKG12089.1 - 0.016 15.7 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 FRG domain Acetyltransf_3 PF13302.1 EKG12090.1 - 1.1e-21 77.5 0.0 1.5e-21 77.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG12090.1 - 1.6e-08 34.6 0.0 2.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG12090.1 - 7.6e-05 22.6 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EKG12090.1 - 0.0048 16.7 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_transf_25 PF01755.12 EKG12091.1 - 0.00013 21.7 0.3 0.0033 17.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) HTH_13 PF11972.3 EKG12092.1 - 0.014 15.2 0.1 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain RVT_1 PF00078.22 EKG12094.1 - 2.4e-12 46.7 0.1 1.4e-11 44.1 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) U5_2-snRNA_bdg PF10597.4 EKG12094.1 - 0.041 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Clathrin PF00637.15 EKG12097.1 - 7.3e-19 67.7 0.3 5.1e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EKG12097.1 - 1.2e-05 24.9 0.4 4.6e-05 23.1 0.3 2.0 1 1 0 1 1 1 1 Ring finger domain TPR_19 PF14559.1 EKG12097.1 - 0.011 15.9 0.2 0.15 12.4 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Prok-RING_1 PF14446.1 EKG12097.1 - 0.019 14.6 0.1 0.019 14.6 0.1 2.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.1 EKG12097.1 - 0.023 14.4 3.3 0.09 12.5 2.3 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.4 EKG12097.1 - 0.056 13.6 0.1 0.85 9.8 0.0 2.7 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 EKG12097.1 - 0.061 13.3 1.2 0.22 11.5 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.1 EKG12097.1 - 0.25 12.0 1.5 2.3 9.0 0.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 EKG12097.1 - 0.39 10.8 2.6 0.29 11.2 0.3 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger DUF155 PF02582.9 EKG12098.1 - 8.2e-42 143.0 0.0 1.1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PBP1_TM PF14812.1 EKG12099.1 - 4.7 7.5 18.6 0.18 12.0 1.2 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.14 EKG12099.1 - 5.8 7.3 6.8 28 5.2 3.2 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_18 PF00704.23 EKG12101.1 - 6.1e-99 331.7 1.8 7.5e-99 331.4 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.17 EKG12102.1 - 2.4e-51 174.7 0.0 4.9e-51 173.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 XFP_N PF09364.5 EKG12103.1 - 1.6e-155 517.3 0.0 2.2e-155 516.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EKG12103.1 - 6.5e-66 221.6 0.0 1.1e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EKG12103.1 - 1.9e-63 213.2 0.0 2.9e-63 212.6 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 EKG12103.1 - 0.01 15.4 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.12 EKG12104.1 - 2.3e-94 316.1 0.0 3.2e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family MFS_1 PF07690.11 EKG12105.1 - 1.5e-29 102.8 38.2 1.9e-29 102.4 25.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 EKG12105.1 - 0.072 13.2 0.1 0.072 13.2 0.0 3.6 2 2 2 4 4 4 0 NfeD-like C-terminal, partner-binding DUF1228 PF06779.9 EKG12105.1 - 0.25 11.3 0.1 0.25 11.3 0.1 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1228) GATase PF00117.23 EKG12106.1 - 1.5e-12 47.3 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EKG12106.1 - 8.2e-05 22.1 0.1 0.00032 20.1 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 DUF336 PF03928.9 EKG12107.1 - 1.5e-34 118.5 0.6 1.8e-34 118.4 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Saccharop_dh PF03435.13 EKG12108.1 - 2.7e-22 79.3 0.2 1.5e-21 76.8 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EKG12108.1 - 0.064 13.5 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EKG12108.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.14 EKG12109.1 - 2.2e-40 136.3 10.2 2.5e-40 136.2 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Elf1 PF05129.8 EKG12109.1 - 0.0019 17.8 0.4 0.0027 17.3 0.3 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 EKG12109.1 - 0.0075 16.0 3.1 0.012 15.4 2.1 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EKG12109.1 - 0.025 14.2 1.2 0.035 13.7 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 EKG12109.1 - 0.056 12.9 4.0 0.06 12.8 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-C2HC5 PF06221.8 EKG12109.1 - 0.081 12.6 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF1364 PF07102.7 EKG12109.1 - 0.084 12.7 0.8 0.12 12.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) zf-BED PF02892.10 EKG12109.1 - 0.091 12.5 6.4 0.74 9.6 0.7 2.4 1 1 1 2 2 2 0 BED zinc finger zf-FCS PF06467.9 EKG12109.1 - 0.13 11.8 2.2 1 9.0 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif Sgf11 PF08209.6 EKG12109.1 - 0.15 11.4 1.2 0.59 9.4 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CarbpepA_inh PF02977.10 EKG12109.1 - 0.58 9.7 3.5 4.3 7.0 2.4 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.1 EKG12109.1 - 1.1 9.6 6.2 0.94 9.8 0.6 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.10 EKG12109.1 - 3.6 7.2 5.7 2 8.0 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger PHD PF00628.24 EKG12110.1 - 2e-07 30.5 12.1 3.2e-07 29.9 8.4 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EKG12110.1 - 0.00081 18.6 6.3 0.0014 17.8 4.3 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EKG12110.1 - 3.1 7.5 12.2 0.11 12.1 3.5 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MFS_1 PF07690.11 EKG12111.1 - 1.3e-29 103.0 43.8 1.9e-29 102.5 30.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_3 PF07859.8 EKG12112.1 - 8.8e-48 162.6 0.1 1.2e-47 162.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG12112.1 - 1.9e-07 30.1 0.1 4e-07 29.1 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EKG12112.1 - 1.1e-05 25.4 0.1 1.3e-05 25.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG12112.1 - 1.6e-05 24.2 0.1 0.0051 16.0 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG12112.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EKG12112.1 - 0.0023 16.6 0.0 0.0035 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) AXE1 PF05448.7 EKG12112.1 - 0.011 14.2 0.0 0.1 11.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF3085 PF11284.3 EKG12112.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) FAD_binding_3 PF01494.14 EKG12113.1 - 2.3e-06 26.8 0.0 2.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ACP_syn_III PF08545.5 EKG12113.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CN_hydrolase PF00795.17 EKG12114.1 - 1.9e-28 99.0 0.0 3.2e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EKG12114.1 - 1.7e-24 86.0 0.0 1e-23 83.4 0.0 2.2 2 1 0 2 2 2 1 NAD synthase Asn_synthase PF00733.16 EKG12114.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase DUF155 PF02582.9 EKG12115.1 - 6.2e-56 189.0 1.7 9.1e-56 188.5 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2931 PF11153.3 EKG12115.1 - 0.026 13.8 0.2 0.1 11.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2931) UPF0449 PF15136.1 EKG12115.1 - 0.035 14.3 0.0 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Isy1 PF06246.7 EKG12116.1 - 9.1e-83 277.5 0.3 1e-82 277.3 0.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Ufd2P_core PF10408.4 EKG12116.1 - 0.08 11.1 0.1 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core CCDC-167 PF15188.1 EKG12116.1 - 0.098 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 mRNA_cap_enzyme PF01331.14 EKG12117.1 - 2.4e-54 183.9 0.7 5.8e-54 182.6 0.1 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EKG12117.1 - 9.4e-18 64.4 0.3 4.1e-17 62.4 0.2 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EKG12117.1 - 1.5e-06 27.7 0.1 0.00028 20.3 0.1 2.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain WHEP-TRS PF00458.15 EKG12117.1 - 0.085 12.5 0.0 0.46 10.2 0.0 2.2 2 0 0 2 2 2 0 WHEP-TRS domain FKBP_N PF01346.13 EKG12117.1 - 0.11 12.4 2.0 0.22 11.5 1.4 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Peptidase_M48 PF01435.13 EKG12118.1 - 8.5e-38 130.1 0.0 1.1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M13 PF01431.16 EKG12118.1 - 0.14 11.3 0.6 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M13 Sec1 PF00995.18 EKG12119.1 - 1.6e-141 472.7 0.0 1.8e-141 472.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SUV3_C PF12513.3 EKG12120.1 - 1.9e-16 59.2 0.3 4.2e-16 58.1 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EKG12120.1 - 2e-10 40.3 0.0 5.9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XRN_N PF03159.13 EKG12120.1 - 0.0033 16.8 0.2 0.0095 15.3 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Kei1 PF08552.6 EKG12121.1 - 1.6e-51 174.7 2.1 1.9e-51 174.4 1.4 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2975 PF11188.3 EKG12121.1 - 0.06 13.0 0.2 0.06 13.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Zn_clus PF00172.13 EKG12122.1 - 0.00019 21.2 11.6 0.00034 20.4 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexokinase_2 PF03727.11 EKG12123.1 - 2.3e-67 226.7 0.0 3.2e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EKG12123.1 - 2.5e-52 177.1 0.0 9.1e-52 175.3 0.0 2.0 2 1 0 2 2 2 1 Hexokinase Hemerythrin PF01814.18 EKG12124.1 - 6.7e-11 42.4 4.8 9.9e-11 41.9 3.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DASH_Hsk3 PF08227.6 EKG12124.1 - 0.22 11.7 1.1 0.78 9.9 0.0 2.5 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like HEAT_2 PF13646.1 EKG12125.1 - 4.9e-17 62.0 0.1 4.2e-16 58.9 0.0 2.0 1 1 1 2 2 2 1 HEAT repeats HEAT_PBS PF03130.11 EKG12125.1 - 7.5e-13 47.6 0.0 0.0021 18.3 0.0 3.5 3 0 0 3 3 3 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EKG12125.1 - 1.1e-07 32.1 0.2 0.0084 16.5 0.0 3.6 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EKG12125.1 - 1.4e-06 27.9 0.3 0.74 10.0 0.0 3.9 4 0 0 4 4 4 3 HEAT repeat Cohesin_HEAT PF12765.2 EKG12125.1 - 0.027 14.4 0.0 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion TFIIS_C PF01096.13 EKG12126.1 - 4.5e-16 58.1 4.3 4.5e-16 58.1 3.0 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EKG12126.1 - 0.00062 19.3 5.5 0.0007 19.2 0.9 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EKG12126.1 - 0.033 13.9 1.6 0.033 13.9 1.1 2.6 2 1 1 3 3 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 EKG12126.1 - 0.045 13.4 11.3 0.34 10.6 1.2 3.4 3 1 0 3 3 3 0 Nudix N-terminal C1_1 PF00130.17 EKG12126.1 - 0.048 13.4 0.4 0.048 13.4 0.3 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 EKG12126.1 - 0.063 12.7 11.8 1.7 8.2 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-B_box PF00643.19 EKG12126.1 - 0.12 12.2 6.0 19 5.2 0.1 3.2 3 0 0 3 3 3 0 B-box zinc finger Zn-ribbon_8 PF09723.5 EKG12126.1 - 0.14 12.1 9.2 4.1 7.4 0.0 3.3 3 1 0 3 3 3 0 Zinc ribbon domain zf-trcl PF13451.1 EKG12126.1 - 0.2 11.2 7.2 2.6 7.7 0.1 3.4 3 0 0 3 3 3 0 Probable zinc-binding domain Baculo_LEF5_C PF11792.3 EKG12126.1 - 0.24 10.8 5.0 2.1 7.8 0.0 3.4 4 0 0 4 4 4 0 Baculoviridae late expression factor 5 C-terminal domain DUF2072 PF09845.4 EKG12126.1 - 0.38 10.6 6.3 2.2 8.2 0.1 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) HNH PF01844.18 EKG12126.1 - 0.4 10.5 3.7 0.82 9.5 0.0 2.8 3 0 0 3 3 3 0 HNH endonuclease NOB1_Zn_bind PF08772.6 EKG12126.1 - 0.47 10.3 5.8 7.8 6.4 0.4 3.0 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_5 PF14634.1 EKG12126.1 - 0.52 10.0 6.8 5.8 6.7 0.2 2.6 2 1 0 2 2 2 0 zinc-RING finger domain RRN7 PF11781.3 EKG12126.1 - 0.77 9.3 12.5 1.2 8.7 0.2 4.0 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Lar_restr_allev PF14354.1 EKG12126.1 - 0.83 9.9 10.3 2.1 8.7 0.2 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.6 EKG12126.1 - 1.2 8.8 12.5 1.4 8.6 1.0 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain RecR PF02132.10 EKG12126.1 - 1.4 8.3 6.7 0.4 10.1 0.8 2.6 2 1 0 2 2 2 0 RecR protein IBR PF01485.16 EKG12126.1 - 6.3 6.7 11.5 1.7 8.5 0.4 3.0 1 1 1 2 2 2 0 IBR domain Cas_CXXC_CXXC PF09706.5 EKG12126.1 - 6.6 6.9 7.2 16 5.7 0.4 2.8 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-ribbon_3 PF13248.1 EKG12126.1 - 9 5.6 16.2 11 5.3 0.1 3.6 3 1 1 4 4 4 0 zinc-ribbon domain Nipped-B_C PF12830.2 EKG12127.1 - 1.6e-56 190.9 5.8 5.1e-54 182.7 0.4 3.6 3 1 1 4 4 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EKG12127.1 - 2.5e-08 33.6 0.4 1.4e-07 31.3 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EKG12127.1 - 3e-06 27.1 1.9 0.015 15.1 0.1 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EKG12127.1 - 3.3e-05 24.1 1.4 0.014 15.6 0.3 5.0 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 EKG12127.1 - 0.00055 19.7 3.3 0.032 14.3 0.0 4.8 4 1 2 6 6 6 1 HEAT repeat Glyco_hydro_47 PF01532.15 EKG12128.1 - 2.2e-99 333.1 0.0 2.7e-99 332.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2036 PF09724.4 EKG12129.1 - 8.5e-20 71.1 0.0 9.5e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) RhoGEF PF00621.15 EKG12130.1 - 2.3e-23 83.0 0.0 4.9e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EKG12130.1 - 4.2e-05 23.1 0.0 6.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2580 PF10824.3 EKG12131.1 - 0.082 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2580) Cpn60_TCP1 PF00118.19 EKG12132.1 - 1.6e-143 478.8 12.7 1.9e-143 478.6 8.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 EKG12133.1 - 2e-21 76.3 0.0 3.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EKG12133.1 - 7.9e-21 73.7 0.4 1.5e-20 72.8 0.3 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EKG12133.1 - 7.8e-16 57.8 0.0 2.9e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain DUF3533 PF12051.3 EKG12134.1 - 8.1e-98 327.6 8.1 1e-97 327.2 5.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF1206 PF06724.6 EKG12134.1 - 0.56 10.0 0.1 0.56 10.0 0.0 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Glyco_hydro_61 PF03443.9 EKG12135.1 - 3.3e-42 144.7 0.0 7.2e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DIM1 PF02966.11 EKG12136.1 - 8.5e-63 209.7 0.6 9.4e-63 209.6 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EKG12136.1 - 0.00035 20.6 0.5 0.00057 19.9 0.4 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.15 EKG12136.1 - 0.012 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Myb_DNA-bind_6 PF13921.1 EKG12137.1 - 0.00026 21.0 0.7 0.0012 18.8 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG12137.1 - 0.0039 17.2 0.2 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_33 PF13592.1 EKG12137.1 - 0.022 14.2 0.5 0.063 12.8 0.1 1.9 2 0 0 2 2 2 0 Winged helix-turn helix EMP24_GP25L PF01105.19 EKG12138.1 - 2.4e-48 164.3 0.2 2.7e-48 164.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FAD_binding_1 PF00667.15 EKG12138.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain LSM PF01423.17 EKG12139.1 - 3.7e-16 58.4 0.0 6.5e-16 57.6 0.0 1.4 2 0 0 2 2 2 1 LSM domain PITH PF06201.8 EKG12140.1 - 2.5e-30 105.2 0.1 2.9e-30 105.0 0.1 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.8 EKG12140.1 - 0.065 13.0 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal Nfu_N PF08712.6 EKG12140.1 - 0.14 11.8 0.4 0.25 10.9 0.3 1.5 1 1 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Snf7 PF03357.16 EKG12141.1 - 5.1e-36 123.6 14.8 5.1e-36 123.6 10.3 1.3 2 0 0 2 2 2 1 Snf7 Silic_transp PF03842.8 EKG12141.1 - 0.15 10.1 0.5 0.18 9.8 0.3 1.1 1 0 0 1 1 1 0 Silicon transporter Nsp1_C PF05064.8 EKG12141.1 - 3.5 7.3 8.1 0.1 12.2 0.6 2.1 3 0 0 3 3 3 0 Nsp1-like C-terminal region AAA PF00004.24 EKG12142.1 - 5.8e-91 301.5 0.0 1.1e-46 158.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKG12142.1 - 7.6e-13 48.0 0.3 3.2e-05 23.1 0.0 3.2 4 0 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKG12142.1 - 1.5e-11 44.6 6.1 0.00051 20.0 0.1 5.4 4 2 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EKG12142.1 - 2.2e-11 44.6 0.2 6.9e-06 26.8 0.0 3.7 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EKG12142.1 - 4.4e-11 42.6 0.1 0.0006 19.5 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG12142.1 - 7.2e-11 42.3 1.3 0.0032 17.6 0.0 5.0 4 2 0 4 4 3 2 AAA domain AAA_2 PF07724.9 EKG12142.1 - 7.2e-10 39.0 0.0 0.00048 20.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EKG12142.1 - 8.8e-10 38.6 0.0 0.0017 18.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EKG12142.1 - 1.2e-09 38.1 0.0 0.0014 18.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EKG12142.1 - 2.2e-08 33.4 0.0 0.0016 17.5 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EKG12142.1 - 9.4e-08 32.4 0.0 0.0018 18.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EKG12142.1 - 1.2e-07 30.7 0.1 0.0043 15.8 0.0 2.6 2 1 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 EKG12142.1 - 1.5e-07 31.5 0.0 0.018 15.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EKG12142.1 - 3.7e-07 29.8 0.6 0.06 13.1 0.0 3.7 3 0 0 3 3 3 2 Part of AAA domain AAA_28 PF13521.1 EKG12142.1 - 7.1e-07 29.3 0.0 0.032 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EKG12142.1 - 1.8e-06 27.3 0.1 0.023 13.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EKG12142.1 - 2.5e-06 27.2 0.5 0.43 10.2 0.0 4.2 3 1 0 4 4 4 2 NACHT domain IstB_IS21 PF01695.12 EKG12142.1 - 2.6e-06 26.9 0.2 0.019 14.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 EKG12142.1 - 4.5e-06 26.1 2.2 1.9 7.8 0.1 4.6 3 1 0 4 4 4 2 AAA domain KaiC PF06745.8 EKG12142.1 - 5.3e-06 25.7 0.1 0.024 13.7 0.0 2.9 3 0 0 3 3 3 2 KaiC ATP-synt_ab PF00006.20 EKG12142.1 - 7.9e-06 25.5 0.0 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 EKG12142.1 - 8.9e-06 25.6 0.0 0.048 13.5 0.0 2.9 2 0 0 2 2 2 2 Shikimate kinase Cytidylate_kin2 PF13189.1 EKG12142.1 - 1.4e-05 25.0 0.0 0.012 15.5 0.0 3.1 3 0 0 3 3 3 1 Cytidylate kinase-like family AAA_3 PF07726.6 EKG12142.1 - 2.4e-05 23.9 0.0 0.097 12.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EKG12142.1 - 6e-05 22.6 0.0 0.36 10.3 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EKG12142.1 - 6.8e-05 21.8 0.1 0.25 10.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.10 EKG12142.1 - 8.6e-05 21.4 0.0 0.058 12.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 EKG12142.1 - 9.4e-05 22.4 0.0 0.3 11.1 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EKG12142.1 - 9.6e-05 21.4 0.0 0.04 12.8 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EKG12142.1 - 0.00029 21.1 0.0 0.26 11.5 0.0 2.8 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 EKG12142.1 - 0.00033 20.4 0.0 1.7 8.2 0.0 3.5 2 2 1 3 3 3 1 Archaeal ATPase Sigma54_activat PF00158.21 EKG12142.1 - 0.00039 19.9 0.0 0.14 11.5 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain UPF0079 PF02367.12 EKG12142.1 - 0.00059 19.4 0.1 0.47 10.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 EKG12142.1 - 0.0013 18.6 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EKG12142.1 - 0.0023 17.5 0.4 2.5 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EKG12142.1 - 0.0026 17.4 0.1 1.1 8.9 0.0 3.2 2 1 0 3 3 3 1 NTPase AAA_24 PF13479.1 EKG12142.1 - 0.0055 16.3 0.5 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EKG12142.1 - 0.006 16.2 0.1 0.82 9.2 0.0 3.4 4 0 0 4 4 3 1 Chloramphenicol phosphotransferase-like protein PhoH PF02562.11 EKG12142.1 - 0.0085 15.3 0.3 0.96 8.6 0.0 2.6 3 0 0 3 3 2 1 PhoH-like protein Bac_DnaA PF00308.13 EKG12142.1 - 0.02 14.5 0.0 2.9 7.4 0.0 3.0 2 1 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.12 EKG12142.1 - 0.027 13.3 0.1 1.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 T2SE PF00437.15 EKG12142.1 - 0.048 12.5 0.0 3.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF2075 PF09848.4 EKG12142.1 - 0.059 12.3 0.2 9.2 5.1 0.0 2.6 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.11 EKG12142.1 - 0.06 12.1 0.0 6.6 5.4 0.0 2.6 2 0 0 2 2 2 0 AFG1-like ATPase PduV-EutP PF10662.4 EKG12142.1 - 0.15 11.5 0.0 8.8 5.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DHC_N1 PF08385.7 EKG12143.1 - 4.1e-190 633.0 4.4 4.1e-190 633.0 3.1 4.6 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EKG12143.1 - 5.3e-130 433.6 6.7 5.3e-130 433.6 4.7 4.9 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EKG12143.1 - 9.3e-110 367.7 0.0 9.3e-110 367.7 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EKG12143.1 - 4.1e-77 258.7 0.0 1e-76 257.5 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EKG12143.1 - 4.8e-45 153.1 0.1 2.4e-44 150.8 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EKG12143.1 - 2.1e-41 141.6 0.3 2.9e-40 137.9 0.1 2.8 2 1 0 2 2 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EKG12143.1 - 5.3e-39 133.9 9.1 5.3e-39 133.9 6.3 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EKG12143.1 - 4.2e-31 107.5 0.1 1.8e-12 47.1 0.0 6.6 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EKG12143.1 - 4.8e-19 68.5 0.0 7.9e-18 64.5 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EKG12143.1 - 5.3e-16 58.9 0.0 0.012 15.8 0.0 6.2 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 EKG12143.1 - 3.1e-13 50.0 0.0 0.0021 18.2 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EKG12143.1 - 2.1e-12 47.1 0.1 0.0043 16.9 0.0 5.4 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EKG12143.1 - 1.5e-10 41.9 0.2 0.037 14.8 0.0 6.6 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.1 EKG12143.1 - 1.3e-08 35.1 5.8 0.054 13.8 0.0 6.3 6 0 0 6 6 6 2 AAA domain T2SE PF00437.15 EKG12143.1 - 2.3e-08 33.2 0.0 0.097 11.5 0.0 3.9 4 0 0 4 4 4 3 Type II/IV secretion system protein AAA_14 PF13173.1 EKG12143.1 - 1.4e-07 31.4 0.0 0.25 11.2 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.1 EKG12143.1 - 1.5e-07 30.8 0.1 0.02 14.3 0.1 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EKG12143.1 - 1.4e-06 27.9 0.4 0.083 12.3 0.0 4.8 4 0 0 4 4 3 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EKG12143.1 - 2e-06 27.9 20.3 0.15 11.9 0.0 9.1 9 1 1 10 10 10 2 AAA ATPase domain AAA_19 PF13245.1 EKG12143.1 - 4e-06 26.4 0.1 0.89 9.3 0.0 4.9 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EKG12143.1 - 2.8e-05 23.3 1.3 0.5 9.4 0.0 3.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EKG12143.1 - 4.9e-05 22.5 2.0 0.47 9.5 0.0 4.3 4 0 0 4 4 3 2 Zeta toxin RNA_helicase PF00910.17 EKG12143.1 - 0.00022 21.3 0.2 2.9 8.1 0.0 5.3 5 0 0 5 5 5 1 RNA helicase DUF258 PF03193.11 EKG12143.1 - 0.00026 20.2 0.0 1.7 7.8 0.0 3.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKG12143.1 - 0.0016 18.7 13.1 0.13 12.5 0.0 6.1 7 0 0 7 7 4 2 ABC transporter MobB PF03205.9 EKG12143.1 - 0.0027 17.4 0.6 4.7 6.9 0.1 3.6 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EKG12143.1 - 0.0039 16.6 3.1 0.64 9.3 0.0 4.6 5 0 0 5 5 4 1 AAA domain AAA_10 PF12846.2 EKG12143.1 - 0.012 15.1 7.8 1.3 8.3 0.0 5.0 4 0 0 4 4 4 0 AAA-like domain PduV-EutP PF10662.4 EKG12143.1 - 0.032 13.7 0.5 6.6 6.2 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FAD_binding_4 PF01565.18 EKG12144.1 - 4.2e-14 52.1 0.0 6.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EKG12144.1 - 6e-05 22.4 0.0 9.4e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain F-box-like PF12937.2 EKG12146.1 - 0.0009 18.9 0.4 0.003 17.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like Treacle PF03546.9 EKG12146.1 - 0.001 17.9 0.5 0.0014 17.4 0.4 1.1 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle F-box PF00646.28 EKG12146.1 - 0.034 13.7 0.7 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 F-box domain HET PF06985.6 EKG12147.1 - 1.1e-24 87.1 0.0 2.3e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) M_domain PF12938.2 EKG12147.1 - 0.2 11.4 0.5 0.31 10.8 0.4 1.2 1 0 0 1 1 1 0 M domain of GW182 FpoO PF10621.4 EKG12148.1 - 0.12 12.5 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO p450 PF00067.17 EKG12149.1 - 3.1e-37 128.1 0.0 5.8e-37 127.2 0.0 1.4 1 1 1 2 2 2 1 Cytochrome P450 CBM_48 PF02922.13 EKG12152.1 - 0.028 14.4 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Aldedh PF00171.17 EKG12154.1 - 4.1e-76 256.1 0.0 5e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ubiq_cyt_C_chap PF03981.7 EKG12155.1 - 4.2e-31 107.6 0.1 5.2e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone K_oxygenase PF13434.1 EKG12156.1 - 4.2e-15 55.4 0.1 2.6e-09 36.4 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EKG12156.1 - 5.5e-14 52.7 0.0 5e-12 46.3 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG12156.1 - 1.2e-05 25.4 0.2 0.018 15.1 0.1 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EKG12156.1 - 1.4e-05 24.9 4.1 0.0009 19.0 0.9 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG12156.1 - 4.8e-05 23.3 0.4 0.026 14.4 0.3 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG12156.1 - 0.0005 19.2 0.0 0.016 14.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EKG12156.1 - 0.00056 18.9 3.0 0.61 8.9 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EKG12156.1 - 0.00071 18.7 0.1 0.0042 16.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EKG12156.1 - 0.0018 16.8 0.0 0.084 11.3 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EKG12156.1 - 0.0027 17.7 1.9 0.098 12.6 0.0 3.5 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG12156.1 - 0.0069 15.3 1.0 0.033 13.1 0.1 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein 3HCDH_N PF02737.13 EKG12156.1 - 0.0086 15.7 0.5 2.7 7.6 0.2 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EKG12156.1 - 0.013 14.9 0.1 0.055 12.9 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MR_MLE_C PF13378.1 EKG12156.1 - 0.026 14.5 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Enolase C-terminal domain-like Pyr_redox PF00070.22 EKG12156.1 - 0.039 14.3 3.1 6.1 7.3 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EKG12156.1 - 0.052 13.5 0.2 0.58 10.1 0.0 2.7 4 0 0 4 4 4 0 TrkA-N domain ketoacyl-synt PF00109.21 EKG12157.1 - 2.5e-57 194.2 1.1 2.5e-57 194.2 0.8 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG12157.1 - 2.3e-34 117.7 1.4 4.7e-34 116.7 0.6 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EKG12157.1 - 4.6e-06 25.8 0.1 2.1e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EKG12157.1 - 0.0027 17.1 4.6 0.0058 16.0 0.1 2.8 3 1 1 4 4 4 1 Thiolase, C-terminal domain NicO PF03824.11 EKG12158.1 - 7.3e-43 146.8 9.2 9.4e-43 146.5 6.4 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 EKG12158.1 - 0.0019 17.0 3.1 0.01 14.6 0.1 2.1 2 0 0 2 2 2 2 Wnt-binding factor required for Wnt secretion DUF4234 PF14018.1 EKG12158.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) PX PF00787.19 EKG12159.1 - 6.5e-18 64.5 0.0 2.5e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EKG12159.1 - 2.2e-12 46.7 15.5 4.7e-08 32.5 2.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like SpecificRecomb PF10136.4 EKG12159.1 - 0.094 10.7 0.6 0.14 10.1 0.4 1.2 1 0 0 1 1 1 0 Site-specific recombinase Ribosomal_S24e PF01282.14 EKG12160.1 - 3.5e-36 122.8 0.0 4.9e-36 122.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EKG12160.1 - 0.0099 15.3 0.7 0.012 15.0 0.5 1.3 1 0 0 1 1 1 1 RRXRR protein Methyltransf_16 PF10294.4 EKG12161.1 - 1.8e-23 82.9 0.1 3e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EKG12161.1 - 5.3e-08 32.3 0.0 8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EKG12161.1 - 6.6e-07 29.8 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG12161.1 - 2.5e-06 26.9 0.0 4.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EKG12161.1 - 0.03 14.0 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EKG12161.1 - 0.037 14.0 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EKG12161.1 - 0.039 14.4 0.1 0.13 12.7 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EKG12161.1 - 0.048 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 EKG12161.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EKG12161.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.15 EKG12161.1 - 0.13 11.3 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ecl1 PF12855.2 EKG12162.1 - 3.6e-16 58.1 1.7 6.6e-16 57.3 1.2 1.4 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 EKG12162.1 - 0.0038 17.0 0.3 0.009 15.8 0.2 1.6 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 EKG12162.1 - 0.034 13.4 3.2 0.096 11.9 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF581) DUF2256 PF10013.4 EKG12162.1 - 3.6 7.4 5.1 1.3 8.8 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) NAD_binding_10 PF13460.1 EKG12163.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Ring_hydroxyl_A PF00848.14 EKG12164.1 - 1e-25 90.6 1.0 7.9e-25 87.7 0.7 1.9 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) STb_secrete PF09075.5 EKG12164.1 - 0.23 11.3 1.8 0.77 9.6 0.1 2.5 2 1 1 3 3 3 0 Heat-stable enterotoxin B, secretory Pro_racemase PF05544.6 EKG12165.1 - 1.2e-40 139.3 0.0 1.7e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 Proline racemase EF-hand_1 PF00036.27 EKG12167.1 - 2.8e-41 135.6 12.8 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKG12167.1 - 1.7e-36 124.1 5.8 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EKG12167.1 - 8.5e-35 118.1 12.2 6.8e-16 57.6 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EKG12167.1 - 1.2e-30 102.6 8.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKG12167.1 - 5.2e-26 88.7 9.7 1.4e-06 27.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EKG12167.1 - 1.3e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EKG12167.1 - 2.6e-09 36.7 1.9 0.00056 19.6 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EKG12167.1 - 1.5e-08 34.6 0.1 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EKG12167.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EKG12167.1 - 4.4e-07 29.7 2.1 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EKG12167.1 - 0.00014 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EKG12167.1 - 0.00023 20.7 0.2 0.075 12.5 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein Tenui_NCP PF04876.7 EKG12167.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EKG12167.1 - 0.0026 17.7 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EKG12167.1 - 0.0083 16.4 1.3 2.5 8.4 0.0 2.5 1 1 2 3 3 3 2 Toprim-like DUF3349 PF11829.3 EKG12167.1 - 0.021 15.2 0.4 12 6.4 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EKG12167.1 - 0.14 11.8 2.5 0.83 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EKG12167.1 - 0.38 10.3 4.1 0.99 9.0 1.1 2.2 1 1 0 2 2 2 0 RloB-like protein PB1 PF00564.19 EKG12167.1 - 0.45 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EKG12168.1 - 1.6e-18 66.1 2.6 1.6e-18 66.1 1.8 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EKG12168.1 - 4e-11 42.9 2.0 4e-11 42.9 1.4 2.4 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EKG12168.1 - 0.018 14.6 9.6 0.05 13.1 1.6 2.5 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.1 EKG12168.1 - 0.02 15.2 0.8 0.097 13.0 0.5 2.2 1 1 1 2 2 2 0 DNA repair REX1-B Syntaxin_2 PF14523.1 EKG12168.1 - 0.03 14.3 1.8 0.03 14.3 1.3 2.6 2 1 0 2 2 2 0 Syntaxin-like protein Mitofilin PF09731.4 EKG12168.1 - 0.61 8.6 6.9 3.6 6.1 5.0 1.6 1 1 0 1 1 1 0 Mitochondrial inner membrane protein SlyX PF04102.7 EKG12168.1 - 6.2 7.2 13.1 10 6.5 0.1 4.2 3 1 1 4 4 4 0 SlyX Alpha-amylase PF00128.19 EKG12169.1 - 2.2e-33 116.0 0.0 3.7e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain 3A PF00803.13 EKG12169.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 2 0 0 2 2 2 0 3A/RNA2 movement protein family Mito_carr PF00153.22 EKG12170.1 - 3.1e-46 155.0 9.4 1.9e-17 62.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein VPS28 PF03997.7 EKG12171.1 - 0.0055 16.3 0.2 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 VPS28 protein RVT_connect PF06815.8 EKG12171.1 - 0.043 13.7 0.9 0.18 11.6 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase connection domain DUF3374 PF11854.3 EKG12171.1 - 0.064 11.5 0.1 0.083 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3374) PEP-utilisers_N PF05524.8 EKG12171.1 - 0.29 10.9 6.3 2.6 7.8 4.2 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal SnoaL_2 PF12680.2 EKG12172.1 - 0.0032 17.8 0.1 0.0044 17.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EKG12172.1 - 0.088 12.3 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Metalloenzyme PF01676.13 EKG12174.1 - 1.7e-75 253.6 0.1 1.9e-75 253.4 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EKG12174.1 - 2.3e-71 239.6 0.0 3.6e-71 239.0 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EKG12174.1 - 8.4e-08 31.9 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EKG12174.1 - 1.7e-05 24.1 0.0 8.5e-05 21.8 0.0 2.2 2 1 0 2 2 2 1 Sulfatase PglZ PF08665.7 EKG12174.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 PglZ domain Alk_phosphatase PF00245.15 EKG12174.1 - 0.054 12.1 0.0 0.43 9.1 0.0 2.0 2 0 0 2 2 2 0 Alkaline phosphatase Med9 PF07544.8 EKG12175.1 - 1.8e-18 66.0 0.2 1.5e-17 63.0 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Golgin_A5 PF09787.4 EKG12175.1 - 0.07 11.6 0.3 0.079 11.4 0.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1993 PF09351.5 EKG12175.1 - 0.079 12.8 0.3 0.15 11.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) SlyX PF04102.7 EKG12175.1 - 0.38 11.1 0.2 0.38 11.1 0.1 3.1 3 1 1 4 4 4 0 SlyX Spc42p PF11544.3 EKG12175.1 - 0.38 10.7 0.2 0.38 10.7 0.1 1.9 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF3708 PF12501.3 EKG12175.1 - 3.3 7.5 6.8 0.44 10.3 1.4 1.8 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Mito_fiss_reg PF05308.6 EKG12175.1 - 5.3 6.3 13.8 11 5.2 2.0 2.3 1 1 1 2 2 2 0 Mitochondrial fission regulator TPP_enzyme_N PF02776.13 EKG12176.1 - 3.3e-35 121.0 0.0 5.4e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EKG12176.1 - 3.9e-25 88.2 0.1 1.1e-24 86.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EKG12176.1 - 3.7e-13 49.3 0.0 8.2e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TauD PF02668.11 EKG12177.1 - 1.2e-48 166.0 0.1 1.4e-48 165.8 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EKG12177.1 - 0.019 15.4 0.2 2 8.9 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily WLM PF08325.5 EKG12178.1 - 2.4e-45 154.6 0.3 6.2e-45 153.3 0.0 1.8 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 EKG12178.1 - 8.4e-07 28.9 0.2 2e-06 27.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Vir_act_alpha_C PF10400.4 EKG12178.1 - 0.034 14.4 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 Virulence activator alpha C-term BLOC1_2 PF10046.4 EKG12179.1 - 0.05 13.7 0.3 0.058 13.5 0.2 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mito_carr PF00153.22 EKG12180.1 - 2.2e-55 184.3 0.6 9.7e-20 70.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 EKG12181.1 - 9.1e-18 64.2 0.0 5.9e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.17 EKG12181.1 - 1e-15 57.6 0.0 3e-12 46.4 0.0 3.4 3 1 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.13 EKG12181.1 - 0.00011 22.0 1.0 0.00021 21.0 0.7 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Oxysterol_BP PF01237.13 EKG12182.1 - 2e-56 190.9 0.0 5.1e-56 189.6 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein RRM_6 PF14259.1 EKG12184.1 - 3.1e-06 27.0 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG12184.1 - 4.9e-06 26.0 0.0 1.3e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U3_assoc_6 PF08640.6 EKG12185.1 - 9.6e-27 92.5 3.6 1.8e-26 91.6 0.2 2.6 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 Suf PF05843.9 EKG12185.1 - 0.0036 17.0 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Frag1 PF10277.4 EKG12186.1 - 9.1e-41 139.6 11.5 9.1e-41 139.6 8.0 2.7 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 EKG12186.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Prp19_bind PF06991.6 EKG12187.1 - 5.2 6.2 7.5 9.8 5.3 5.2 1.3 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Sugar_tr PF00083.19 EKG12188.1 - 4.9e-42 144.0 23.3 6.7e-42 143.6 16.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG12188.1 - 8.9e-16 57.5 28.2 8.9e-16 57.5 19.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily FHA PF00498.21 EKG12189.1 - 1.5e-13 50.6 0.0 3.2e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 EKG12189.1 - 0.022 13.2 32.1 0.028 12.9 22.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2730 PF10805.3 EKG12190.1 - 0.27 11.0 6.2 0.38 10.5 1.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) CENP-F_leu_zip PF10473.4 EKG12190.1 - 0.31 10.8 0.0 0.31 10.8 0.0 4.3 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 EKG12190.1 - 0.84 9.5 40.3 0.014 15.3 17.1 3.1 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion p450 PF00067.17 EKG12191.1 - 7.2e-06 24.7 0.0 8.9e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Photo_RC PF00124.14 EKG12191.1 - 0.063 12.2 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre protein p450 PF00067.17 EKG12192.1 - 1.1e-38 133.0 0.0 1.5e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EKG12193.1 - 1.8e-06 27.3 0.0 2.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ANTAR PF03861.9 EKG12193.1 - 0.00015 21.2 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 ANTAR domain SPX PF03105.14 EKG12194.1 - 2.8e-40 138.8 0.0 3.4e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.1 EKG12194.1 - 1e-06 28.3 7.8 1.7e-06 27.5 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG12194.1 - 1.8e-06 27.5 8.8 3.5e-06 26.6 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EKG12194.1 - 2.9e-06 27.0 11.2 5.6e-06 26.1 7.3 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EKG12194.1 - 2.2e-05 24.1 11.4 5.1e-05 23.0 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKG12194.1 - 6.6e-05 22.8 12.4 0.00015 21.7 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG12194.1 - 6.8e-05 22.4 10.8 0.00013 21.5 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 EKG12194.1 - 0.056 12.9 8.6 0.11 12.0 6.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TerY-C PF15616.1 EKG12194.1 - 0.076 12.9 1.0 0.14 12.1 0.7 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_UBOX PF13445.1 EKG12194.1 - 0.081 12.6 9.9 0.24 11.1 6.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EKG12194.1 - 0.14 12.3 2.6 0.28 11.2 1.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EKG12194.1 - 0.27 11.0 2.3 0.51 10.2 1.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.7 EKG12194.1 - 0.54 10.0 3.3 2.1 8.2 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_4 PF14570.1 EKG12194.1 - 0.63 9.6 8.0 0.15 11.6 3.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_jaz PF12171.3 EKG12195.1 - 1.1e-11 44.4 12.5 4.4e-11 42.5 4.6 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG12195.1 - 5e-09 36.0 2.9 5e-09 36.0 2.0 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EKG12195.1 - 6.8e-08 32.5 6.9 0.00018 21.5 2.3 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EKG12195.1 - 2e-05 24.5 5.0 0.089 13.1 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG12195.1 - 0.0012 19.0 6.3 0.19 12.1 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-LYAR PF08790.6 EKG12195.1 - 0.007 16.0 1.3 2.2 8.0 0.1 2.6 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger LIM PF00412.17 EKG12195.1 - 0.089 12.8 4.7 0.25 11.4 0.4 2.3 2 0 0 2 2 2 0 LIM domain DUF2387 PF09526.5 EKG12195.1 - 0.1 12.5 5.5 0.72 9.8 2.4 2.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-C2H2_6 PF13912.1 EKG12195.1 - 0.52 10.2 8.8 0.19 11.6 1.0 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG12195.1 - 0.6 10.5 3.5 0.95 9.8 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain MFS_1 PF07690.11 EKG12196.1 - 5.1e-24 84.6 41.6 8.4e-20 70.7 24.8 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily ubiquitin PF00240.18 EKG12198.1 - 1.1e-15 56.7 0.0 3.9e-15 54.9 0.0 1.9 2 1 1 3 3 3 1 Ubiquitin family zf-AN1 PF01428.11 EKG12198.1 - 5.2e-10 39.0 10.8 8.3e-10 38.3 7.5 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Rad60-SLD PF11976.3 EKG12198.1 - 2.3e-08 33.6 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EKG12198.1 - 0.0006 19.5 0.2 0.00097 18.8 0.2 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 EKG12198.1 - 0.04 14.1 0.1 0.05 13.8 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Acyl-CoA_dh_1 PF00441.19 EKG12199.1 - 1.1e-31 109.9 0.8 1.9e-31 109.2 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EKG12199.1 - 1.4e-19 69.6 0.1 4.5e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EKG12199.1 - 1.6e-19 69.1 0.2 3.8e-19 67.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EKG12199.1 - 6.2e-06 26.4 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG12199.1 - 2.2e-05 25.0 0.3 6.9e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain CoaE PF01121.15 EKG12199.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase MFS_1 PF07690.11 EKG12200.1 - 1.9e-19 69.6 13.1 2.2e-18 66.0 6.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily 7tm_3 PF00003.17 EKG12200.1 - 0.0053 16.1 0.4 0.018 14.4 0.2 2.0 1 1 1 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Sugar_tr PF00083.19 EKG12200.1 - 0.075 11.5 14.4 0.24 9.9 10.0 1.7 1 1 0 1 1 1 0 Sugar (and other) transporter MFS_1 PF07690.11 EKG12201.1 - 8.1e-26 90.5 47.4 8.1e-26 90.5 32.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12201.1 - 7.9e-06 24.7 19.4 7.9e-06 24.7 13.5 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter DUF1129 PF06570.6 EKG12201.1 - 4.2 6.6 18.1 0.047 12.9 5.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) SLAC1 PF03595.12 EKG12202.1 - 1.7e-72 243.8 34.9 1.9e-72 243.6 24.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel WSC PF01822.14 EKG12205.1 - 5.4e-14 51.8 9.9 5.4e-14 51.8 6.9 2.1 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.5 EKG12205.1 - 3.3e-08 32.6 1.0 3.3e-08 32.6 0.7 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EKG12205.1 - 0.0015 18.0 1.1 0.0033 17.0 0.8 1.5 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.1 EKG12205.1 - 0.026 14.9 0.0 0.071 13.5 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1191 PF06697.7 EKG12205.1 - 0.033 13.0 0.2 0.047 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4448 PF14610.1 EKG12205.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1517 PF07466.6 EKG12205.1 - 0.041 12.8 3.6 0.064 12.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Trp_oprn_chp PF09534.5 EKG12205.1 - 0.4 10.2 4.3 0.15 11.6 0.3 2.2 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) COesterase PF00135.23 EKG12207.1 - 2e-98 330.4 0.6 7.6e-98 328.5 0.4 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG12207.1 - 8.2e-06 25.5 0.5 0.00041 20.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG12207.1 - 0.0063 15.7 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Cupin_2 PF07883.6 EKG12208.1 - 1.3e-10 40.5 0.0 2.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EKG12208.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EKG12208.1 - 0.0068 16.0 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain CENP-C_C PF11699.3 EKG12208.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.5 1 1 0 1 1 1 0 Mif2/CENP-C like Cupin_3 PF05899.7 EKG12208.1 - 0.11 11.8 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) FAA_hydrolase PF01557.13 EKG12209.1 - 9e-44 149.5 0.0 1.6e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EKG12209.1 - 2.6e-18 65.9 0.0 2.3e-17 62.9 0.0 2.8 3 0 0 3 3 3 1 Fumarylacetoacetase N-terminal Amidohydro_1 PF01979.15 EKG12209.1 - 4.4e-18 66.0 0.5 9.9e-17 61.5 0.2 2.8 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKG12209.1 - 8e-14 51.2 0.1 3.1e-13 49.3 0.1 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EKG12209.1 - 2.5e-06 27.7 10.1 0.00018 21.6 6.9 2.8 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG12209.1 - 0.0071 15.5 2.4 0.032 13.4 0.1 2.4 2 0 0 2 2 2 1 Amidohydrolase family Fungal_trans_2 PF11951.3 EKG12211.1 - 1e-26 93.4 8.8 3.4e-14 52.2 0.0 2.8 1 1 1 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG12212.1 - 2.6e-27 95.4 38.1 5.1e-27 94.5 26.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4149 PF13664.1 EKG12212.1 - 0.0028 17.6 2.1 0.0028 17.6 1.5 2.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4149) Sugar_tr PF00083.19 EKG12213.1 - 3.3e-90 302.8 22.4 4e-90 302.5 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG12213.1 - 4.1e-16 58.6 42.7 4.7e-09 35.4 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transaldolase PF00923.14 EKG12214.1 - 5.3e-05 22.5 0.0 8.1e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Transaldolase HLH PF00010.21 EKG12215.1 - 4.6e-09 35.8 1.3 8e-09 35.0 0.9 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NESP55 PF06390.7 EKG12215.1 - 0.8 9.0 6.8 0.055 12.8 1.2 1.6 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) MFS_1 PF07690.11 EKG12216.1 - 2.1e-44 151.6 33.4 2.1e-44 151.6 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPMT PF05724.6 EKG12217.1 - 3.2e-31 108.4 0.0 2.5e-29 102.2 0.0 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 EKG12217.1 - 0.00013 22.3 0.0 0.00023 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG12217.1 - 0.00031 20.7 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG12217.1 - 0.00042 20.8 0.0 0.00066 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG12217.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG12217.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG12217.1 - 0.023 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 EKG12217.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.14 EKG12218.1 - 6.8e-18 65.4 0.4 1.1e-16 61.5 0.0 2.6 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EKG12218.1 - 3.8e-05 23.1 0.0 0.042 13.2 0.0 2.5 3 0 0 3 3 3 2 Peptidase C65 Otubain adh_short_C2 PF13561.1 EKG12219.1 - 6.2e-23 81.8 0.0 8.2e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG12219.1 - 3e-16 59.8 0.3 5e-16 59.0 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG12219.1 - 0.0049 16.5 0.1 0.018 14.6 0.0 1.9 1 1 2 3 3 3 1 KR domain DUF1365 PF07103.6 EKG12220.1 - 1.4e-06 27.6 0.0 2e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DUF1365 PF07103.6 EKG12221.1 - 1.6e-05 24.0 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) DEAD PF00270.24 EKG12222.1 - 6.6e-44 149.3 0.0 1.4e-43 148.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG12222.1 - 4.2e-22 77.7 0.0 9.3e-22 76.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EKG12222.1 - 0.0013 18.2 0.3 0.0027 17.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF3843 PF12954.2 EKG12222.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) TRP PF06011.7 EKG12223.1 - 7.4e-153 509.2 29.7 9.1e-153 508.9 20.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EKG12223.1 - 1.1e-44 151.9 0.6 1.7e-44 151.2 0.4 1.4 1 0 0 1 1 1 1 ML-like domain Pkinase PF00069.20 EKG12224.1 - 1.8e-14 53.5 0.0 7.6e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain ICL PF00463.16 EKG12225.1 - 1.7e-285 947.1 3.2 2e-285 946.9 2.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EKG12225.1 - 7.6e-13 48.2 0.1 5.2e-11 42.2 0.0 2.9 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.11 EKG12226.1 - 2.7e-33 115.1 37.0 4e-33 114.6 25.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12226.1 - 1e-07 30.9 15.0 1e-07 30.9 10.4 1.8 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EKG12226.1 - 1.1e-05 23.8 4.8 1.8e-05 23.1 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA_2 PF07724.9 EKG12227.1 - 1.4e-45 155.2 0.0 1.9e-44 151.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EKG12227.1 - 2.5e-25 89.1 0.0 2.1e-13 50.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EKG12227.1 - 1.7e-23 82.2 2.2 2e-23 82.0 0.1 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EKG12227.1 - 4.5e-15 55.6 0.0 6.2e-10 38.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKG12227.1 - 6.5e-15 55.5 12.7 5.4e-06 26.5 0.0 6.3 4 2 3 7 7 6 2 AAA ATPase domain AAA_22 PF13401.1 EKG12227.1 - 7.3e-14 52.0 0.1 2.7e-05 24.3 0.0 3.7 2 2 1 3 3 3 2 AAA domain Clp_N PF02861.15 EKG12227.1 - 2.9e-09 36.6 8.1 2.9e-05 23.9 0.1 4.2 4 0 0 4 4 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 EKG12227.1 - 1.5e-08 34.2 0.0 2.4e-05 23.8 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EKG12227.1 - 2.5e-07 31.5 4.7 0.011 16.5 0.0 3.9 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 EKG12227.1 - 4.3e-07 29.5 0.0 0.029 13.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EKG12227.1 - 7.5e-07 29.5 0.0 0.095 13.0 0.0 3.7 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EKG12227.1 - 1.8e-06 27.5 1.9 0.056 13.2 0.1 3.3 3 0 0 3 3 2 2 Part of AAA domain T2SE PF00437.15 EKG12227.1 - 1.8e-05 23.7 0.4 0.0031 16.4 0.0 3.1 3 1 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EKG12227.1 - 3.2e-05 23.1 0.2 0.1 11.7 0.1 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EKG12227.1 - 5.4e-05 23.0 9.2 0.025 14.2 0.2 5.1 5 1 0 5 5 4 1 Archaeal ATPase AAA_33 PF13671.1 EKG12227.1 - 5.7e-05 23.0 0.1 0.2 11.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EKG12227.1 - 8.1e-05 22.6 2.3 0.85 9.5 0.0 3.9 3 1 1 4 4 4 2 AAA domain ResIII PF04851.10 EKG12227.1 - 9e-05 22.3 0.2 0.1 12.4 0.0 3.9 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EKG12227.1 - 0.00026 21.1 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.1 EKG12227.1 - 0.00036 19.9 0.0 0.29 10.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EKG12227.1 - 0.00039 19.8 2.4 0.49 9.7 0.0 3.6 3 1 1 4 4 4 2 AAA domain MobB PF03205.9 EKG12227.1 - 0.00051 19.7 0.1 0.85 9.3 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EKG12227.1 - 0.00064 19.3 0.0 1.1 8.8 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EKG12227.1 - 0.0011 18.8 0.0 0.0095 15.8 0.0 2.3 2 0 0 2 2 2 1 Torsin DUF258 PF03193.11 EKG12227.1 - 0.0014 17.8 0.0 0.98 8.5 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EKG12227.1 - 0.0021 17.5 5.4 0.34 10.3 0.2 4.8 3 2 0 4 4 4 1 AAA-like domain AAA_24 PF13479.1 EKG12227.1 - 0.0042 16.6 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EKG12227.1 - 0.0049 16.5 0.0 0.65 9.6 0.0 3.0 3 0 0 3 3 2 1 NACHT domain ABC_tran PF00005.22 EKG12227.1 - 0.0095 16.2 3.5 0.81 9.9 0.0 3.3 4 0 0 4 4 3 1 ABC transporter NTPase_1 PF03266.10 EKG12227.1 - 0.016 14.9 0.0 0.94 9.1 0.0 3.2 3 0 0 3 3 3 0 NTPase SRP54 PF00448.17 EKG12227.1 - 0.019 14.4 0.3 4.3 6.7 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EKG12227.1 - 0.023 14.6 0.0 2.3 8.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain Peptidase_M16 PF00675.15 EKG12227.1 - 0.055 13.2 2.6 8.3 6.1 1.3 2.7 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) UPF0079 PF02367.12 EKG12227.1 - 0.083 12.5 0.0 19 4.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Snapin_Pallidin PF14712.1 EKG12227.1 - 0.19 12.0 7.5 0.86 9.9 1.1 3.1 2 0 0 2 2 2 0 Snapin/Pallidin V_ATPase_I PF01496.14 EKG12227.1 - 2.1 6.0 4.2 3.9 5.2 2.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EKG12227.1 - 2.2 8.5 0.0 2.2 8.5 0.0 4.6 3 2 0 4 4 3 0 AAA domain Macoilin PF09726.4 EKG12227.1 - 2.5 6.3 12.4 0.64 8.2 5.4 2.0 2 0 0 2 2 2 0 Transmembrane protein Herpes_capsid PF06112.6 EKG12228.1 - 4.2 7.3 8.7 9.4 6.2 6.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HEAT PF02985.17 EKG12229.1 - 2.4e-16 58.2 10.7 3e-05 23.7 0.0 10.5 13 0 0 13 13 13 3 HEAT repeat HEAT_EZ PF13513.1 EKG12229.1 - 1.4e-15 57.2 14.3 4e-07 30.3 0.0 9.5 8 2 2 10 10 10 1 HEAT-like repeat HEAT_2 PF13646.1 EKG12229.1 - 1.3e-12 47.8 15.9 2.3e-05 24.5 0.0 7.6 3 2 5 8 8 8 5 HEAT repeats IBN_N PF03810.14 EKG12229.1 - 9.2e-11 41.5 4.1 8.2e-10 38.4 0.6 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EKG12229.1 - 5.3e-06 25.9 0.4 1.2 8.4 0.0 4.7 4 1 0 4 4 4 2 CLASP N terminal RIX1 PF08167.7 EKG12229.1 - 9.1e-06 25.4 0.5 0.021 14.5 0.0 4.4 2 1 3 5 5 5 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EKG12229.1 - 0.00019 20.3 0.5 0.021 13.5 0.1 3.1 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 EKG12229.1 - 0.039 14.4 3.5 1.3e+02 3.5 0.0 6.2 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Arm PF00514.18 EKG12229.1 - 0.29 11.0 9.6 49 3.9 0.0 5.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat PP2C PF00481.16 EKG12230.1 - 1.8e-36 125.8 0.0 3.1e-29 102.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EKG12230.1 - 0.0011 18.3 0.0 0.0081 15.5 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C TBPIP PF07106.8 EKG12231.1 - 0.00054 19.5 7.0 0.00089 18.8 4.9 1.3 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EKG12231.1 - 0.0029 16.6 7.3 0.0045 15.9 5.1 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EKG12231.1 - 0.0056 16.3 13.8 0.0092 15.5 9.5 1.2 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 EKG12231.1 - 0.013 14.5 10.0 0.02 13.9 6.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FH2 PF02181.18 EKG12231.1 - 0.025 13.4 3.9 0.038 12.8 2.7 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain V_ATPase_I PF01496.14 EKG12231.1 - 0.064 11.1 2.2 0.082 10.7 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EKG12231.1 - 0.079 11.3 6.9 0.12 10.7 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EKG12231.1 - 0.12 12.0 8.5 0.19 11.3 5.9 1.2 1 0 0 1 1 1 0 Mnd1 family DUF1664 PF07889.7 EKG12231.1 - 0.13 12.0 2.2 0.26 11.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EKG12231.1 - 0.13 10.8 7.8 0.19 10.3 5.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 EKG12231.1 - 0.13 10.5 6.7 0.2 10.0 4.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Prominin PF05478.6 EKG12231.1 - 0.14 9.7 3.5 0.2 9.1 2.4 1.1 1 0 0 1 1 1 0 Prominin TMPIT PF07851.8 EKG12231.1 - 0.18 10.8 5.3 0.27 10.2 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein GrpE PF01025.14 EKG12231.1 - 0.21 11.0 8.0 0.36 10.3 5.6 1.3 1 0 0 1 1 1 0 GrpE DUF972 PF06156.8 EKG12231.1 - 0.22 11.8 6.7 0.52 10.6 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3373 PF11853.3 EKG12231.1 - 0.24 9.8 2.0 0.38 9.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3584 PF12128.3 EKG12231.1 - 0.3 8.3 9.4 0.48 7.6 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3810 PF12725.2 EKG12231.1 - 0.34 9.7 1.9 0.48 9.2 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) FlaC_arch PF05377.6 EKG12231.1 - 0.46 10.4 3.1 3.6 7.5 2.1 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Peptidase_S49_N PF08496.5 EKG12231.1 - 1.3 8.8 7.8 2.4 7.9 5.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4337 PF14235.1 EKG12231.1 - 1.5 8.5 6.7 2.5 7.9 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) MSG PF02349.10 EKG12231.1 - 1.8 8.6 16.4 3.4 7.6 11.4 1.4 1 0 0 1 1 1 0 Major surface glycoprotein RRM_1 PF00076.17 EKG12232.1 - 6.3e-44 147.4 0.6 1.6e-19 69.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG12232.1 - 9.8e-35 118.3 0.1 2.7e-17 62.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EKG12232.1 - 7.5e-28 96.6 0.1 1.6e-27 95.5 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EKG12232.1 - 2.5e-25 88.0 0.1 5e-09 35.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKG12232.1 - 0.0042 16.8 0.0 0.055 13.3 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.6 EKG12232.1 - 0.17 11.9 0.0 9.5 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA binding domain Cyt-b5 PF00173.23 EKG12233.1 - 3.7e-18 65.0 0.4 3.8e-17 61.8 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EKG12233.1 - 3.7e-09 36.9 18.3 3.7e-09 36.9 12.7 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily ATP_synt_I PF03899.10 EKG12233.1 - 0.028 14.5 2.1 0.49 10.5 0.2 2.3 2 0 0 2 2 2 0 ATP synthase I chain Anth_synt_I_N PF04715.8 EKG12233.1 - 0.064 13.2 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DLH PF01738.13 EKG12235.1 - 0.0047 16.2 0.0 0.058 12.6 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family SnoaL PF07366.7 EKG12235.1 - 0.016 14.7 0.0 0.067 12.7 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EKG12235.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Mg_trans_NIPA PF05653.9 EKG12236.1 - 1.4e-111 372.2 15.6 1.8e-111 371.9 10.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EKG12236.1 - 1.2e-06 28.6 5.0 1.2e-06 28.6 3.5 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EKG12236.1 - 0.00016 21.7 8.4 0.00016 21.7 5.8 3.0 2 1 0 2 2 2 1 EamA-like transporter family DUF2420 PF10336.4 EKG12237.1 - 3.6e-15 55.5 0.0 6.1e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 EKG12238.1 - 2.1e-17 63.1 0.0 3.4e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EKG12238.1 - 9e-08 31.9 0.1 1.5e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EKG12238.1 - 0.0015 18.6 1.7 0.015 15.3 0.2 2.3 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) Allexi_40kDa PF05549.6 EKG12238.1 - 0.0062 15.8 0.3 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 Allexivirus 40kDa protein Apc4 PF12896.2 EKG12239.1 - 9.6e-53 178.6 0.0 1.4e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EKG12239.1 - 8.9e-05 21.9 0.0 0.0011 18.4 0.0 2.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Med16 PF11635.3 EKG12239.1 - 0.055 11.4 0.0 0.094 10.6 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 16 BCNT PF07572.7 EKG12240.1 - 6.8e-27 93.2 1.9 6.8e-27 93.2 1.3 2.0 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF3377 PF11857.3 EKG12241.1 - 0.062 12.9 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RNR_inhib PF08591.5 EKG12242.1 - 8.5e-21 74.7 0.0 2e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Mur_ligase PF01225.20 EKG12242.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Iso_dh PF00180.15 EKG12244.1 - 6e-66 222.7 0.0 6.7e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4081 PF13312.1 EKG12245.1 - 0.082 12.8 0.1 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4081) NTP_transf_2 PF01909.18 EKG12245.1 - 0.098 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Nucleotidyltransferase domain Ferric_reduct PF01794.14 EKG12246.1 - 2.4e-17 63.1 10.6 7.4e-17 61.6 7.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EKG12246.1 - 1e-12 48.2 0.0 1.1e-10 41.6 0.0 2.5 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG12246.1 - 5e-10 39.1 0.0 2.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EKG12246.1 - 0.094 13.2 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain GMC_oxred_N PF00732.14 EKG12247.1 - 4.8e-55 186.7 0.0 6.3e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG12247.1 - 9.1e-28 97.3 0.0 1.6e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG12247.1 - 7e-06 25.1 5.6 0.00042 19.3 3.9 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG12247.1 - 0.00013 21.8 0.0 0.00052 19.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG12247.1 - 0.00021 20.2 2.3 0.002 17.0 1.6 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EKG12247.1 - 0.0011 19.1 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EKG12247.1 - 0.0034 17.3 0.3 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 EKG12247.1 - 0.0042 16.0 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EKG12247.1 - 0.044 12.8 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EKG12247.1 - 0.093 12.4 0.3 0.6 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EKG12247.1 - 0.095 13.1 0.1 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.1 EKG12248.1 - 6.8e-64 215.9 51.1 8e-64 215.7 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG12248.1 - 1.1e-15 56.9 40.7 1.6e-15 56.4 28.2 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EKG12249.1 - 1.2e-30 106.4 43.2 2e-29 102.3 26.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12249.1 - 7.8e-11 41.2 0.7 7.8e-11 41.2 0.5 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter DUF1228 PF06779.9 EKG12249.1 - 0.0024 17.8 0.3 0.0024 17.8 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Prefoldin_2 PF01920.15 EKG12250.1 - 1.8e-24 85.5 7.6 2.5e-24 85.0 5.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Pkinase PF00069.20 EKG12250.1 - 2.7e-07 30.0 0.0 0.00026 20.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain DUF3752 PF12572.3 EKG12250.1 - 0.19 11.8 3.5 0.32 11.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) TMEM154 PF15102.1 EKG12251.1 - 0.00075 19.2 0.0 0.0026 17.4 0.0 2.0 1 1 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.1 EKG12251.1 - 0.084 12.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) CcmH PF03918.9 EKG12251.1 - 0.16 10.9 0.1 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein MSP1_C PF07462.6 EKG12251.1 - 8.1 4.6 5.1 13 3.9 3.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Adeno_E3_14_5 PF04834.7 EKG12251.1 - 8.2 6.9 8.1 11 6.4 4.1 2.3 2 1 0 2 2 2 0 Early E3 14.5 kDa protein OMPdecase PF00215.19 EKG12253.1 - 4.5e-77 258.4 0.0 5.3e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family SKG6 PF08693.5 EKG12255.1 - 8.4e-09 34.6 0.2 1.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM51 PF15345.1 EKG12255.1 - 0.0013 18.4 0.2 0.0019 17.9 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Mid2 PF04478.7 EKG12255.1 - 0.0067 15.8 0.4 0.011 15.1 0.2 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.15 EKG12255.1 - 0.026 14.1 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Rax2 PF12768.2 EKG12255.1 - 0.037 13.2 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF1517 PF07466.6 EKG12255.1 - 0.31 9.9 1.7 0.49 9.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Esterase_phd PF10503.4 EKG12256.1 - 5.7e-06 25.7 0.1 0.0004 19.7 0.0 2.2 1 1 1 2 2 2 2 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EKG12256.1 - 0.0013 18.5 0.0 0.0027 17.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Amidase PF01425.16 EKG12257.1 - 2.9e-66 224.1 0.1 6e-65 219.8 0.0 2.2 2 0 0 2 2 2 2 Amidase ABM PF03992.11 EKG12258.1 - 5.7e-11 42.2 0.0 7.5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase LigB PF02900.13 EKG12259.1 - 5.7e-48 163.2 0.0 7.2e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.13 EKG12261.1 - 1.7e-14 53.2 0.0 3.2e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Terpene_synth_C PF03936.11 EKG12262.1 - 0.0011 18.2 0.0 0.0047 16.1 0.0 1.9 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain HAD_2 PF13419.1 EKG12263.1 - 3.4e-29 102.2 0.0 4.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG12263.1 - 0.027 14.1 0.0 0.076 12.7 0.0 1.8 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.21 EKG12263.1 - 0.099 13.0 0.0 0.63 10.4 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.3 EKG12263.1 - 0.12 11.3 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Senescence PF06911.7 EKG12265.1 - 0.4 10.3 4.5 1.7 8.3 3.1 1.8 1 1 0 1 1 1 0 Senescence-associated protein PPR_2 PF13041.1 EKG12266.1 - 2.6e-32 110.5 2.0 1e-10 41.3 0.0 7.7 5 2 4 9 9 9 6 PPR repeat family PPR_3 PF13812.1 EKG12266.1 - 5e-29 98.1 0.7 0.0012 18.9 0.0 9.1 9 0 0 9 9 9 6 Pentatricopeptide repeat domain PPR PF01535.15 EKG12266.1 - 2e-17 61.8 4.0 0.011 15.6 0.0 8.4 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.2 EKG12266.1 - 9.4e-13 47.4 0.0 0.0013 18.1 0.0 6.0 6 1 0 6 6 6 4 PPR repeat ECSIT PF06239.6 EKG12266.1 - 0.0049 15.7 0.9 0.29 9.9 0.1 3.6 2 1 2 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway SIMPL PF04402.9 EKG12266.1 - 0.024 14.5 0.1 0.055 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF541) RPM2 PF08579.6 EKG12266.1 - 0.029 14.4 0.4 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 EKG12266.1 - 0.034 14.7 0.0 3 8.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat His_Phos_2 PF00328.17 EKG12267.1 - 2.3e-12 46.9 0.0 7.5e-11 41.9 0.0 2.6 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) MRP-L47 PF06984.8 EKG12267.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) MFS_1 PF07690.11 EKG12268.1 - 1.8e-35 122.2 28.3 2.2e-35 122.0 19.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12268.1 - 3e-07 29.3 18.9 4.4e-07 28.8 13.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Trp_oprn_chp PF09534.5 EKG12268.1 - 0.0053 16.4 1.7 0.0053 16.4 1.2 2.0 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tyrosinase PF00264.15 EKG12269.1 - 1.1e-38 133.6 0.2 1.5e-38 133.2 0.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase COesterase PF00135.23 EKG12270.1 - 2.3e-84 284.0 0.0 3.1e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG12270.1 - 1.6e-09 37.7 0.1 7.4e-09 35.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG12270.1 - 0.0012 18.0 0.1 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EKG12270.1 - 0.0024 16.5 0.0 0.017 13.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EKG12270.1 - 0.039 13.7 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 EKG12271.1 - 3.2e-13 49.4 2.4 1.1e-07 31.2 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain WW PF00397.21 EKG12273.1 - 0.076 12.8 0.0 0.076 12.8 0.0 2.6 3 0 0 3 3 3 0 WW domain DUF1517 PF07466.6 EKG12273.1 - 2.6 6.9 6.7 4.8 6.0 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) CDC45 PF02724.9 EKG12273.1 - 3.1 5.7 7.5 3.9 5.3 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3043 PF11241.3 EKG12273.1 - 6.9 6.2 7.5 1.5 8.3 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Sulfatase PF00884.18 EKG12274.1 - 3.8e-59 200.3 0.1 4.8e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EKG12274.1 - 2.4e-21 75.3 0.7 6.5e-21 73.9 0.5 1.8 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EKG12274.1 - 5.2e-09 35.8 1.1 1.6e-07 30.9 0.8 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EKG12274.1 - 1.1e-05 25.7 0.0 2.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Tox-HDC PF15656.1 EKG12274.1 - 0.061 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature DUF229 PF02995.12 EKG12274.1 - 0.066 11.6 0.0 0.099 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Acetyltransf_1 PF00583.19 EKG12276.1 - 9.3e-08 32.0 0.0 3e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EKG12276.1 - 0.00087 19.8 0.0 0.064 13.8 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG12276.1 - 0.0023 18.0 0.0 0.0067 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG12276.1 - 0.022 14.6 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GMC_oxred_N PF00732.14 EKG12277.1 - 2.8e-46 158.0 0.0 4.7e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG12277.1 - 5.2e-28 98.1 0.0 1.2e-26 93.7 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EKG12277.1 - 8.2e-09 34.8 0.2 0.00068 18.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG12277.1 - 1.1e-06 27.7 0.3 7.8e-05 21.6 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG12277.1 - 0.00029 20.7 0.0 0.00075 19.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG12277.1 - 0.0016 18.4 0.5 0.01 15.8 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG12277.1 - 0.0038 16.3 0.4 0.0097 15.0 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EKG12277.1 - 0.023 13.7 0.2 0.033 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EKG12277.1 - 0.19 10.7 0.5 0.31 10.0 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 4HBT PF03061.17 EKG12281.1 - 1.9e-05 24.6 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MoeA_C PF03454.10 EKG12281.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) FAD_binding_4 PF01565.18 EKG12283.1 - 9.8e-19 67.2 3.1 1.8e-18 66.3 2.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG12283.1 - 1.1e-08 34.8 0.0 2.8e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like LEM PF03020.10 EKG12284.1 - 0.12 11.8 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 LEM domain Polyketide_cyc2 PF10604.4 EKG12284.1 - 0.13 12.4 3.0 2.7 8.1 0.2 2.3 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF1769 PF08588.5 EKG12285.1 - 8.6e-20 70.4 0.0 2.2e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF3628 PF12300.3 EKG12285.1 - 7.5 6.5 13.2 1.9 8.5 4.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) SDA1 PF05285.7 EKG12286.1 - 4.8e-92 308.6 35.9 4.8e-92 308.6 24.9 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EKG12286.1 - 5.2e-22 77.8 0.1 1.5e-21 76.3 0.1 1.9 1 0 0 1 1 1 1 NUC130/3NT domain DUF2356 PF10189.4 EKG12286.1 - 0.0094 15.0 0.0 0.035 13.1 0.0 1.8 2 0 0 2 2 2 1 Conserved protein (DUF2356) BTB_2 PF02214.17 EKG12291.1 - 0.0031 17.6 0.0 0.32 11.2 0.0 2.8 3 0 0 3 3 3 2 BTB/POZ domain GST_N PF02798.15 EKG12292.1 - 5.7e-10 39.2 0.0 1.5e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG12292.1 - 7.1e-09 36.0 0.0 1.9e-08 34.6 0.0 1.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG12292.1 - 4.6e-08 32.9 0.0 8.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG12292.1 - 1e-07 32.0 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG12292.1 - 2.4e-07 30.6 0.0 4.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG12292.1 - 5.1e-07 29.4 0.0 7.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.7 EKG12293.1 - 0.00063 19.5 0.0 0.00073 19.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Pyr_redox_3 PF13738.1 EKG12294.1 - 0.0076 16.3 0.0 0.18 11.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EBP PF05241.7 EKG12295.1 - 1.6e-51 174.0 6.3 2.5e-51 173.4 4.4 1.2 1 0 0 1 1 1 1 Emopamil binding protein GAT PF03127.9 EKG12298.1 - 6.4e-14 51.7 0.9 1.1e-13 50.9 0.6 1.3 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EKG12298.1 - 0.00011 21.8 0.1 0.004 16.7 0.0 2.3 2 0 0 2 2 2 1 VHS domain REC114-like PF15165.1 EKG12298.1 - 0.091 12.4 0.3 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Ribosomal_S25 PF03297.10 EKG12299.1 - 2.7e-39 133.4 5.8 2.9e-39 133.3 4.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EKG12299.1 - 0.0076 15.7 0.2 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 EKG12299.1 - 0.021 14.9 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 EKG12299.1 - 0.022 14.4 0.1 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 MarR family FeoC PF09012.5 EKG12299.1 - 0.025 14.3 0.6 0.068 12.8 0.0 1.8 1 1 1 2 2 2 0 FeoC like transcriptional regulator HTH_11 PF08279.7 EKG12299.1 - 0.026 14.1 0.1 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.1 EKG12299.1 - 0.09 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EKG12299.1 - 0.13 11.9 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB SoxD PF04267.7 EKG12301.1 - 0.09 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family Cyt-b5 PF00173.23 EKG12303.1 - 4.6e-10 39.1 0.0 7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.7 EKG12304.1 - 3.6e-72 242.2 0.1 4.5e-72 241.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EKG12304.1 - 0.00025 20.3 0.0 0.00037 19.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG12304.1 - 0.00062 19.2 0.0 0.00097 18.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKG12304.1 - 0.002 18.0 0.0 0.011 15.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EKG12304.1 - 0.006 17.0 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 EKG12304.1 - 0.013 15.4 0.0 0.044 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.5 EKG12304.1 - 0.019 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2834 PF11196.3 EKG12305.1 - 2e-05 24.6 3.9 0.15 12.1 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2834) 7TM_GPCR_Sri PF10327.4 EKG12305.1 - 0.016 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri Arf PF00025.16 EKG12306.1 - 8.6e-45 152.0 0.1 3.1e-43 147.0 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EKG12306.1 - 5.1e-13 48.4 0.0 1.8e-06 26.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EKG12306.1 - 7.6e-10 38.4 0.0 2e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 EKG12306.1 - 1.7e-08 33.9 0.0 2e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKG12306.1 - 7.5e-08 31.7 0.0 2.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EKG12306.1 - 6e-07 29.9 0.0 8.6e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EKG12306.1 - 8.8e-07 28.5 0.0 3.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKG12306.1 - 9.1e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG12306.1 - 0.03 13.6 0.0 0.068 12.4 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EKG12306.1 - 0.082 13.0 0.1 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Pox_polyA_pol PF03296.8 EKG12308.1 - 0.57 9.7 1.9 1.5 8.3 0.1 2.1 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase nucleotidyltransferase domain Cyt_c_ox_IV PF12270.3 EKG12309.1 - 0.014 15.1 0.3 0.014 15.1 0.2 1.7 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV HATPase_c PF02518.21 EKG12310.1 - 3.5e-20 71.7 0.0 8.2e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EKG12310.1 - 3e-12 46.3 0.0 9.5e-12 44.7 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EKG12310.1 - 1.3e-05 25.3 0.0 3.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain Mitofilin PF09731.4 EKG12311.1 - 0.0036 16.0 10.0 0.0036 16.0 7.0 2.1 2 0 0 2 2 1 1 Mitochondrial inner membrane protein Spore_coat_CotO PF14153.1 EKG12311.1 - 0.023 14.1 49.2 0.033 13.6 8.9 2.4 2 0 0 2 2 2 0 Spore coat protein CotO Dynamin_N PF00350.18 EKG12311.1 - 0.33 10.7 16.2 0.1 12.3 2.6 2.2 2 0 0 2 2 2 0 Dynamin family Daxx PF03344.10 EKG12311.1 - 0.39 9.1 58.6 0.19 10.2 27.0 2.1 2 0 0 2 2 2 0 Daxx Family RNA_polI_A34 PF08208.6 EKG12311.1 - 0.96 9.0 39.2 2.7 7.6 2.7 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4045 PF13254.1 EKG12311.1 - 1.2 8.3 26.8 0.83 8.8 8.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Adaptin_binding PF10199.4 EKG12311.1 - 1.5 9.1 37.3 1.3 9.2 12.3 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Caldesmon PF02029.10 EKG12311.1 - 1.6 7.0 52.6 0.59 8.4 22.8 2.1 2 0 0 2 2 2 0 Caldesmon SPX PF03105.14 EKG12311.1 - 1.7 8.3 23.1 1.2 8.8 3.6 2.2 2 0 0 2 2 2 0 SPX domain Ycf1 PF05758.7 EKG12311.1 - 1.9 6.0 35.2 0.54 7.9 5.6 2.0 2 0 0 2 2 2 0 Ycf1 DUF2052 PF09747.4 EKG12311.1 - 4.1 7.2 55.7 1.9 8.3 11.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM60A PF15396.1 EKG12311.1 - 5.1 6.7 18.8 5.7 6.6 4.2 2.4 2 0 0 2 2 2 0 Protein Family FAM60A AUX_IAA PF02309.11 EKG12311.1 - 5.9 6.5 22.4 5.4 6.7 4.3 2.3 2 0 0 2 2 2 0 AUX/IAA family POP1 PF06978.6 EKG12311.1 - 6 6.4 13.4 2.2 7.8 1.4 2.3 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 CENP-T PF15511.1 EKG12311.1 - 6.7 5.8 44.5 1.7 7.7 17.0 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Pal1 PF08316.6 EKG12311.1 - 7.6 6.9 15.3 1.2 9.6 2.4 2.4 2 0 0 2 2 2 0 Pal1 cell morphology protein Pilt PF15453.1 EKG12311.1 - 7.9 6.0 32.5 2.6 7.6 10.7 2.3 2 0 0 2 2 2 0 Protein incorporated later into Tight Junctions SAPS PF04499.10 EKG12311.1 - 8.8 4.8 33.0 0.42 9.1 2.9 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Nop14 PF04147.7 EKG12311.1 - 8.9 4.0 54.3 1.7 6.4 4.1 2.1 2 0 0 2 2 2 0 Nop14-like family Flavin_Reduct PF01613.13 EKG12312.1 - 7e-11 42.2 0.0 9.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Abhydrolase_1 PF00561.15 EKG12313.1 - 3.3e-13 49.7 0.1 2.7e-12 46.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG12313.1 - 2.3e-09 37.4 0.0 4e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG12313.1 - 0.0037 17.0 0.4 0.05 13.3 0.3 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG12313.1 - 0.011 14.9 0.0 0.12 11.5 0.0 2.2 2 1 0 2 2 2 0 Prolyl oligopeptidase family PAP_central PF04928.12 EKG12314.1 - 7.7e-102 339.4 0.0 1.1e-101 338.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EKG12314.1 - 3.5e-41 140.3 0.0 7.7e-41 139.2 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EKG12314.1 - 8.9e-09 35.5 0.0 2.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain p450 PF00067.17 EKG12316.1 - 1.1e-67 228.5 0.0 1.7e-67 227.9 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EKG12317.1 - 1.3e-52 178.6 0.1 8.6e-31 106.7 0.0 4.8 2 2 0 2 2 2 2 AMP-binding enzyme 4HBT_3 PF13622.1 EKG12318.1 - 1.8e-53 181.9 0.2 2.6e-53 181.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EKG12318.1 - 4.1e-28 97.6 0.0 7.7e-14 51.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase HMGL-like PF00682.14 EKG12319.1 - 9e-65 218.6 0.0 1.5e-64 217.9 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EKG12319.1 - 4.2e-22 78.3 0.1 1.2e-21 76.8 0.0 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF1989 PF09347.5 EKG12320.1 - 2.4e-20 72.6 0.0 2.9e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) ORC6 PF05460.8 EKG12321.1 - 0.081 12.0 0.1 0.097 11.7 0.1 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TMEM247 PF15444.1 EKG12321.1 - 0.22 11.3 5.0 0.28 10.9 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 COesterase PF00135.23 EKG12322.1 - 1.8e-53 182.0 0.0 2.5e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG12322.1 - 5.9e-05 22.7 0.1 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold PS_pyruv_trans PF04230.8 EKG12322.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Gly-zipper_OmpA PF13436.1 EKG12324.1 - 4.6 6.9 9.6 12 5.5 2.2 3.3 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain MFS_1 PF07690.11 EKG12326.1 - 0.0087 14.8 3.8 0.013 14.2 2.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EKG12327.1 - 0.0027 16.5 0.2 0.003 16.3 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.20 EKG12328.1 - 4.9e-74 248.7 0.0 6.5e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12328.1 - 1.6e-36 125.7 0.0 2.3e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EKG12328.1 - 2.2e-17 62.9 0.1 4.3e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EKG12328.1 - 2.3e-06 26.7 0.0 8.7e-06 24.8 0.0 1.7 1 1 0 2 2 2 1 Kinase-like YukC PF10140.4 EKG12328.1 - 0.0025 16.4 0.1 0.0038 15.8 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.17 EKG12328.1 - 0.0031 16.8 0.2 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EKG12328.1 - 0.02 13.9 0.1 0.038 13.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 EKG12330.1 - 1.9e-25 89.3 24.2 2.4e-25 89.0 16.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EKG12330.1 - 0.0068 15.9 3.8 0.011 15.2 2.3 1.6 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EKG12331.1 - 4.8e-106 355.0 24.1 5.6e-106 354.8 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG12331.1 - 9.7e-13 47.5 38.0 2.9e-09 36.1 7.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily zf-CCHC PF00098.18 EKG12332.1 - 5.9e-41 136.4 91.2 1.5e-06 27.8 1.7 11.5 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_2 PF13696.1 EKG12332.1 - 1.6e-09 37.0 43.4 0.1 12.0 0.7 9.1 4 3 5 9 9 9 7 Zinc knuckle zf-CCHC_3 PF13917.1 EKG12332.1 - 6e-08 32.2 62.0 0.00059 19.5 0.8 9.4 3 2 6 9 9 9 6 Zinc knuckle zf-CCHC_4 PF14392.1 EKG12332.1 - 0.00021 20.9 72.3 0.3 10.7 1.1 11.3 11 0 0 11 11 11 8 Zinc knuckle zf-CCHC_6 PF15288.1 EKG12332.1 - 0.66 9.6 79.5 0.068 12.8 1.9 10.5 9 2 1 10 10 10 0 Zinc knuckle p450 PF00067.17 EKG12333.1 - 4.4e-51 173.8 0.0 5.6e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FTHFS PF01268.14 EKG12334.1 - 1.1e-258 858.8 0.2 1.4e-258 858.4 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EKG12334.1 - 1.7e-69 231.9 1.2 1.7e-69 231.9 0.8 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EKG12334.1 - 3.8e-39 133.3 0.7 8.7e-39 132.1 0.5 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AA_permease PF00324.16 EKG12336.1 - 7.1e-71 238.9 45.8 8e-71 238.7 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG12336.1 - 5.9e-23 81.0 49.6 7.4e-23 80.7 34.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2373 PF10180.4 EKG12337.1 - 1.5e-19 69.3 0.1 2.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EKG12338.1 - 1.9e-48 164.3 0.1 2.6e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKG12338.1 - 5.8e-13 47.9 0.3 9e-13 47.2 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3650 PF12368.3 EKG12338.1 - 0.08 12.4 0.4 0.18 11.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) Spc97_Spc98 PF04130.8 EKG12340.1 - 2.3e-118 395.9 0.0 2.7e-118 395.6 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Glyco_hydro_72 PF03198.9 EKG12341.1 - 2.3e-102 342.2 2.9 3.6e-102 341.5 2.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EKG12341.1 - 0.00034 19.9 2.2 0.0018 17.5 1.5 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Bac_chlorC PF02043.12 EKG12341.1 - 0.076 12.8 0.4 0.076 12.8 0.3 2.6 3 0 0 3 3 3 0 Bacteriochlorophyll C binding protein MFS_1 PF07690.11 EKG12343.1 - 1.6e-11 43.5 2.1 2.2e-11 43.0 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF605 PF04652.11 EKG12344.1 - 4.6 6.5 10.7 5.5 6.2 7.4 1.1 1 0 0 1 1 1 0 Vta1 like Glyco_hydro_3 PF00933.16 EKG12346.1 - 1.2e-84 283.8 0.0 1.9e-84 283.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG12346.1 - 1.9e-47 161.7 0.2 1e-46 159.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG12346.1 - 3e-21 75.1 0.1 5.7e-21 74.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_transf_8 PF01501.15 EKG12347.1 - 1.2e-07 31.3 1.8 2.1e-06 27.2 1.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EKG12347.1 - 0.012 14.9 0.2 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Mannosyltransferase putative DUF2484 PF10658.4 EKG12347.1 - 0.05 13.7 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) adh_short_C2 PF13561.1 EKG12348.1 - 5e-32 111.5 0.3 5.7e-32 111.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG12348.1 - 3.6e-27 95.3 0.2 4.6e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG12348.1 - 1.2e-14 54.3 0.1 1.5e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG12348.1 - 0.0015 18.0 0.1 0.0026 17.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family His_Phos_1 PF00300.17 EKG12351.1 - 1.3e-31 109.8 0.0 2e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EKG12351.1 - 0.00049 19.5 0.0 0.00086 18.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1168 PF06658.7 EKG12352.1 - 9.4e-44 148.3 14.4 1.5e-43 147.7 10.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) PGA2 PF07543.7 EKG12352.1 - 0.23 11.2 12.4 0.39 10.4 8.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Neur_chan_memb PF02932.11 EKG12352.1 - 0.29 10.9 4.6 0.43 10.4 3.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mnd1 PF03962.10 EKG12352.1 - 0.57 9.8 8.6 0.89 9.1 6.0 1.2 1 0 0 1 1 1 0 Mnd1 family NARP1 PF12569.3 EKG12352.1 - 2 7.0 13.5 2.6 6.7 9.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 EKG12352.1 - 4 7.4 15.4 6.2 6.8 10.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Fungal_trans PF04082.13 EKG12353.1 - 2.7e-26 92.0 0.9 3.6e-26 91.5 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG12354.1 - 3.3e-32 111.5 24.8 3.3e-32 111.5 17.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_4 PF01063.14 EKG12355.1 - 3.5e-25 88.8 0.0 5.5e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EKG12356.1 - 5.8e-17 61.7 0.0 6.8e-16 58.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12356.1 - 3.1e-11 42.8 0.0 6.5e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG12356.1 - 0.084 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RtxA PF07634.6 EKG12357.1 - 1.5 9.2 7.0 14 6.2 0.9 3.0 2 1 0 2 2 2 0 RtxA repeat Pro_isomerase PF00160.16 EKG12358.1 - 3.5e-44 150.7 0.2 5.4e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EKG12358.1 - 4.3e-12 45.4 14.4 1.2e-06 28.0 1.3 2.6 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKG12358.1 - 1e-08 34.4 12.1 1.4e-05 24.4 1.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKG12358.1 - 4.7e-05 22.9 2.4 4.7e-05 22.9 1.7 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG12358.1 - 0.00021 21.8 4.6 0.0042 17.7 1.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKG12358.1 - 0.00028 20.7 1.2 0.00028 20.7 0.9 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKG12358.1 - 0.02 15.0 2.5 3.2 8.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat KIP1 PF07765.7 EKG12358.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 KIP1-like protein TPR_8 PF13181.1 EKG12358.1 - 0.027 14.2 1.7 0.027 14.2 1.1 3.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG12358.1 - 0.06 14.0 1.7 0.06 14.0 1.2 2.6 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG12358.1 - 1.6 9.3 6.5 1.2 9.7 0.8 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 EKG12358.1 - 7.8 6.4 10.0 12 5.9 3.2 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Tyrosinase PF00264.15 EKG12359.1 - 7.6e-46 157.0 0.1 9.3e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Cg6151-P PF10233.4 EKG12360.1 - 0.79 9.7 7.5 8.6 6.3 0.3 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein CG6151-P Rieske PF00355.21 EKG12361.1 - 9.3e-16 57.1 0.0 1.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 EKG12362.1 - 3.5e-30 105.2 0.4 7.3e-29 100.9 0.3 2.1 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) XPG_I PF00867.13 EKG12363.1 - 7.9e-14 51.4 0.0 1.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 XPG I-region Cu-oxidase PF00394.17 EKG12364.1 - 9.5e-32 110.0 0.0 1.8e-30 105.9 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG12364.1 - 3.7e-28 97.6 0.1 3.5e-26 91.2 0.0 2.7 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG12364.1 - 1e-23 83.3 3.9 2.6e-20 72.3 0.3 3.6 2 1 0 2 2 2 2 Multicopper oxidase FAD_binding_4 PF01565.18 EKG12366.1 - 7.2e-26 90.3 0.6 7.2e-26 90.3 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EKG12366.1 - 0.0003 20.6 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Acyl_transf_1 PF00698.16 EKG12367.1 - 8.1e-57 192.9 1.0 1.3e-56 192.2 0.7 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EKG12367.1 - 1.6e-55 187.5 0.0 1.7e-54 184.2 0.0 2.8 3 0 0 3 3 3 1 KR domain PS-DH PF14765.1 EKG12367.1 - 2.2e-51 174.7 0.0 3.8e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EKG12367.1 - 2.7e-41 141.2 0.0 8.9e-41 139.5 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EKG12367.1 - 2.6e-22 78.7 0.1 2.4e-21 75.6 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EKG12367.1 - 1.1e-21 77.0 0.0 1.2e-20 73.8 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EKG12367.1 - 3.6e-16 60.2 0.0 2.3e-15 57.6 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EKG12367.1 - 1.4e-13 50.6 0.0 3.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG12367.1 - 5.9e-13 49.1 0.0 2e-12 47.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG12367.1 - 4.9e-12 45.8 0.0 1.1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG12367.1 - 1.8e-11 44.6 0.0 7.4e-11 42.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG12367.1 - 3.5e-09 36.9 0.0 9.6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG12367.1 - 2.4e-07 30.7 0.1 2.4e-06 27.5 0.0 2.7 4 0 0 4 4 2 1 Methyltransferase domain ADH_N PF08240.7 EKG12367.1 - 7.6e-07 28.8 0.7 1.8e-06 27.6 0.2 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EKG12367.1 - 2.1e-06 27.0 0.0 6.2e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 EKG12367.1 - 0.0008 20.2 0.1 0.0083 16.9 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EKG12367.1 - 0.0012 18.2 0.0 0.0033 16.8 0.0 1.7 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 EKG12367.1 - 0.038 13.3 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Orn_DAP_Arg_deC PF00278.17 EKG12367.1 - 0.045 13.4 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain MTS PF05175.9 EKG12367.1 - 0.059 12.7 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.13 EKG12367.1 - 0.07 12.4 0.0 1.9 7.7 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DUF915 PF06028.6 EKG12367.1 - 0.076 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF938 PF06080.7 EKG12367.1 - 0.19 11.2 0.0 0.6 9.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DREV PF05219.7 EKG12367.1 - 0.39 9.5 0.0 0.78 8.5 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase RrnaAD PF00398.15 EKG12367.1 - 0.5 9.3 0.0 0.82 8.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ketoacyl-synt PF00109.21 EKG12368.1 - 8.7e-11 41.7 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAD_binding_4 PF01565.18 EKG12369.1 - 6.5e-21 74.2 0.8 1.2e-18 66.9 0.5 2.8 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 EKG12369.1 - 7.4e-05 22.5 0.2 0.00018 21.3 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EKG12370.1 - 3.5e-48 164.3 0.0 4e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG12371.1 - 3.3e-59 200.6 0.0 4.3e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Clathrin_bdg PF15045.1 EKG12371.1 - 0.072 12.6 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Ribonuc_L-PSP PF01042.16 EKG12372.1 - 1.8e-34 118.1 0.0 1.9e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_transf_34 PF05637.7 EKG12373.1 - 5.5e-14 52.2 0.0 8.9e-11 41.7 0.0 2.7 1 1 2 3 3 3 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EKG12373.1 - 0.00058 19.2 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Dioxygenase_C PF00775.16 EKG12374.1 - 3.1e-10 39.6 0.1 5.2e-10 38.8 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Sulfotransfer_3 PF13469.1 EKG12375.1 - 0.12 13.3 6.5 0.098 13.5 3.5 1.5 1 1 0 1 1 1 0 Sulfotransferase family MFS_1 PF07690.11 EKG12376.1 - 1.1e-32 113.1 29.4 1.1e-32 113.1 20.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_8 PF00895.15 EKG12376.1 - 4.8 7.4 10.4 7.8 6.7 0.0 3.6 3 0 0 3 3 3 0 ATP synthase protein 8 Abhydrolase_6 PF12697.2 EKG12377.1 - 7.4e-25 88.1 1.7 1.4e-24 87.2 1.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG12377.1 - 1.3e-10 41.2 0.0 6.9e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG12377.1 - 1.1e-06 28.4 1.5 1.5e-05 24.7 1.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EKG12377.1 - 8.9e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 EKG12377.1 - 0.0015 17.0 0.0 0.38 9.1 0.0 2.1 2 0 0 2 2 2 2 Ndr family EthD PF07110.6 EKG12377.1 - 0.021 15.7 0.0 0.86 10.5 0.0 2.7 2 0 0 2 2 2 0 EthD domain Lactonase PF10282.4 EKG12378.1 - 3.3e-22 79.0 0.0 4.6e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Dioxygenase_C PF00775.16 EKG12379.1 - 6.6e-48 162.3 0.0 8.5e-48 162.0 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EKG12379.1 - 1.4e-11 44.1 0.0 2.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Cna_B PF05738.8 EKG12379.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Cna protein B-type domain CarboxypepD_reg PF13620.1 EKG12379.1 - 0.024 14.6 0.0 0.19 11.8 0.0 2.3 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Alginate_lyase PF05426.7 EKG12380.1 - 2e-15 56.9 6.4 3.1e-15 56.2 4.4 1.3 1 0 0 1 1 1 1 Alginate lyase SET PF00856.23 EKG12382.1 - 3.3e-14 53.4 0.0 4.3e-12 46.6 0.0 2.7 2 1 0 2 2 2 1 SET domain TPR_11 PF13414.1 EKG12382.1 - 0.049 13.2 0.1 7.9 6.2 0.0 2.9 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EKG12382.1 - 0.061 13.9 0.5 15 6.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.13 EKG12382.1 - 6.5 6.7 13.0 0.56 10.1 5.2 2.2 2 0 0 2 2 2 0 MYND finger AA_permease_2 PF13520.1 EKG12383.1 - 1.5e-77 260.9 37.0 2.1e-77 260.4 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.21 EKG12384.1 - 4e-23 81.3 0.4 7.6e-23 80.4 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG12384.1 - 1.3e-19 69.9 0.5 3e-19 68.7 0.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EKG12384.1 - 0.0036 17.3 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_18 PF12847.2 EKG12384.1 - 0.028 15.0 0.2 0.043 14.3 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EKG12385.1 - 7.1e-73 245.3 0.1 9e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG12385.1 - 1.9e-14 54.3 0.1 7.4e-14 52.4 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Filo_glycop PF01611.11 EKG12385.1 - 0.19 10.4 0.0 0.34 9.6 0.0 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein Epimerase PF01370.16 EKG12386.1 - 1.1e-23 83.8 0.0 1.9e-23 83.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG12386.1 - 4.6e-09 35.5 0.0 7.5e-09 34.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EKG12386.1 - 2.1e-08 33.2 0.1 1.1e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG12386.1 - 4.8e-08 33.2 0.0 1.3e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EKG12386.1 - 7e-08 31.6 0.0 3.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EKG12386.1 - 4.1e-06 25.9 0.0 0.00035 19.5 0.1 2.6 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Asp PF00026.18 EKG12388.1 - 1e-05 24.9 0.3 1.3e-05 24.6 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease VSP PF03302.8 EKG12388.1 - 0.014 14.0 0.2 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Syndecan PF01034.15 EKG12388.1 - 0.014 15.0 0.9 0.028 14.0 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EKG12388.1 - 0.024 13.9 0.7 0.048 12.9 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BAGE PF08180.6 EKG12388.1 - 3.9 7.3 5.4 3.8 7.3 0.4 2.4 2 0 0 2 2 2 0 B melanoma antigen family Pkinase PF00069.20 EKG12389.1 - 4.2e-71 239.1 0.0 5.2e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12389.1 - 3.1e-32 111.6 0.0 4.9e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG12389.1 - 0.015 15.0 0.7 0.057 13.1 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EKG12389.1 - 0.086 11.8 0.1 0.26 10.3 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GMC_oxred_N PF00732.14 EKG12391.1 - 1.4e-64 218.1 0.0 1.8e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG12391.1 - 4.1e-33 114.7 0.0 1.4e-32 112.9 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EKG12391.1 - 3.2e-05 23.0 0.0 5.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EKG12391.1 - 5.3e-05 22.2 0.0 0.025 13.4 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG12391.1 - 0.0004 20.3 0.1 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG12391.1 - 0.0032 17.5 0.0 0.043 13.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG12391.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG12391.1 - 0.029 13.2 0.0 0.93 8.2 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EKG12391.1 - 0.041 12.7 0.0 0.1 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EKG12391.1 - 0.075 12.7 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKG12391.1 - 0.15 11.0 0.1 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.1 EKG12391.1 - 0.19 10.6 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Mob_synth_C PF06463.8 EKG12392.1 - 1.6e-35 121.5 0.1 1.3e-34 118.6 0.0 2.0 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EKG12392.1 - 8e-21 74.9 0.0 1.6e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EKG12392.1 - 1.1e-05 25.5 0.0 0.00016 21.7 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EKG12392.1 - 0.00022 21.2 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain RNase_H2-Ydr279 PF09468.5 EKG12393.1 - 9.2 5.3 14.0 21 4.1 9.7 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pyr_redox_3 PF13738.1 EKG12394.1 - 1.8e-21 77.1 0.0 9.4e-21 74.8 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG12394.1 - 3.1e-06 27.1 0.0 1.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EKG12394.1 - 2.1e-05 22.9 0.0 0.0012 17.1 0.0 2.4 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EKG12394.1 - 2.7e-05 23.2 0.0 0.0045 15.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EKG12394.1 - 3.5e-05 23.6 0.0 0.015 15.0 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG12394.1 - 0.00016 21.5 0.0 1.9 8.2 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG12394.1 - 0.00039 20.5 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EKG12394.1 - 0.0026 16.9 0.0 0.012 14.7 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG12394.1 - 0.0084 16.0 0.0 0.042 13.8 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.22 EKG12394.1 - 0.036 14.4 1.0 0.72 10.3 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG12394.1 - 0.22 10.5 1.2 0.3 10.1 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain PfkB PF00294.19 EKG12396.1 - 3e-71 240.0 0.1 3.5e-71 239.8 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EKG12396.1 - 0.0013 17.9 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 EKG12397.1 - 5.9e-61 206.1 0.0 1e-60 205.3 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EKG12397.1 - 4.7e-17 62.2 1.2 8.4e-17 61.3 0.8 1.4 1 0 0 1 1 1 1 Telomerase activating protein Est1 zf-C2H2_4 PF13894.1 EKG12398.1 - 0.0002 21.4 8.3 0.056 13.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EKG12398.1 - 0.044 14.0 7.6 0.16 12.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EKG12398.1 - 0.09 12.7 0.2 0.2 11.6 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG12398.1 - 0.091 12.9 8.2 0.22 11.6 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EKG12398.1 - 0.52 10.7 7.9 7 7.2 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EKG12398.1 - 2.4 8.3 8.4 2.4 8.3 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RFXA_RFXANK_bdg PF15289.1 EKG12398.1 - 5.7 7.1 6.1 14 5.9 2.1 2.6 2 1 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain MFS_1 PF07690.11 EKG12399.1 - 8.9e-33 113.4 12.1 1.3e-32 112.9 8.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12399.1 - 4.5e-13 48.5 4.1 6.6e-13 48.0 2.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EKG12399.1 - 0.00013 20.3 0.8 0.00022 19.5 0.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EKG12399.1 - 0.021 12.9 4.8 0.074 11.1 3.3 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.15 EKG12399.1 - 0.15 10.0 1.2 0.2 9.6 0.1 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CN_hydrolase PF00795.17 EKG12401.1 - 1.4e-23 83.1 0.0 2.1e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Syja_N PF02383.13 EKG12402.1 - 1.2e-91 306.8 0.0 2e-91 306.0 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EKG12402.1 - 3.1e-30 103.9 0.0 5.5e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Herpes_UL25 PF01499.11 EKG12402.1 - 1.2 7.4 6.4 2.3 6.4 4.5 1.4 1 0 0 1 1 1 0 Herpesvirus UL25 family Aldolase_II PF00596.16 EKG12404.1 - 6.3e-47 159.5 0.0 7.9e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Gly-zipper_OmpA PF13436.1 EKG12405.1 - 0.86 9.2 5.7 0.27 10.8 1.1 2.1 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Hexapep PF00132.19 EKG12406.1 - 2.6e-07 29.8 2.9 0.0022 17.3 0.5 2.7 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EKG12406.1 - 0.00076 18.8 0.0 0.005 16.1 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EKG12406.1 - 0.0015 18.6 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EKG12406.1 - 0.19 10.2 0.1 0.29 9.6 0.1 1.2 1 0 0 1 1 1 0 L-fucokinase zf-Mss51 PF13824.1 EKG12408.1 - 3.2e-25 87.7 6.5 6e-25 86.8 4.5 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 PROCT PF08084.6 EKG12408.1 - 0.1 12.3 0.6 0.19 11.4 0.4 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain CPSF_A PF03178.10 EKG12409.1 - 2.1e-100 335.9 0.0 2.2e-98 329.3 0.0 3.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EKG12409.1 - 4.1e-64 216.5 0.0 6.8e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 EKG12409.1 - 0.014 15.0 0.0 4.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal DUF2235 PF09994.4 EKG12410.1 - 2.8e-39 135.1 0.0 3.8e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AA_permease_2 PF13520.1 EKG12412.1 - 2.7e-52 177.7 52.2 3.3e-52 177.4 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG12412.1 - 5.7e-15 54.6 43.9 8.8e-15 53.9 30.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3925 PF13063.1 EKG12412.1 - 2.9 8.0 7.4 20 5.2 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3925) His_Phos_2 PF00328.17 EKG12413.1 - 1.6e-56 192.1 0.0 1.9e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Isochorismatase PF00857.15 EKG12414.1 - 2.3e-34 118.8 0.1 2.7e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Oxysterol_BP PF01237.13 EKG12415.1 - 1e-134 448.5 0.0 7.3e-134 445.7 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EKG12415.1 - 4.3e-22 77.6 1.3 1.1e-13 50.9 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EKG12415.1 - 3.2e-19 67.6 0.9 4.6e-07 29.3 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EKG12415.1 - 3e-18 65.9 0.1 1.3e-12 47.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG12415.1 - 3.5e-16 59.2 0.3 4.6e-08 33.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG12415.1 - 2.1e-15 55.2 0.2 8.1e-05 22.5 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat PH PF00169.24 EKG12415.1 - 4.8e-11 42.7 0.1 1e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EKG12415.1 - 1e-06 28.6 0.4 2.9e-06 27.2 0.3 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain HemY_N PF07219.8 EKG12415.1 - 4.8 6.7 9.6 0.17 11.4 0.7 3.1 4 0 0 4 4 4 0 HemY protein N-terminus ATP12 PF07542.6 EKG12416.1 - 6.4e-37 126.2 0.3 6.4e-37 126.2 0.2 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein Fungal_trans PF04082.13 EKG12417.1 - 4.6e-27 94.5 0.0 2.8e-25 88.6 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Spt20 PF12090.3 EKG12418.1 - 1.6e-42 144.9 0.0 1.6e-42 144.9 0.0 5.4 4 2 0 4 4 4 1 Spt20 family Ycf1 PF05758.7 EKG12418.1 - 5.7 4.5 14.0 1.6 6.3 0.1 2.3 2 1 0 2 2 2 0 Ycf1 Kelch_4 PF13418.1 EKG12419.1 - 9.8e-19 66.8 2.1 3.6e-05 23.4 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EKG12419.1 - 8.2e-17 60.7 4.7 7.5e-05 22.5 0.0 5.7 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EKG12419.1 - 1.6e-15 56.4 1.3 0.0001 22.2 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EKG12419.1 - 1.5e-14 53.2 0.0 0.0001 21.7 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 EKG12419.1 - 4.6e-14 52.1 4.5 0.00062 19.8 0.0 6.9 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EKG12419.1 - 4.8e-12 45.1 2.8 0.0034 17.0 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Alpha-L-AF_C PF06964.7 EKG12420.1 - 2.5e-26 92.5 1.5 9.2e-25 87.4 1.1 2.4 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus UBX PF00789.15 EKG12421.1 - 1.1e-12 47.7 0.0 2.4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EKG12421.1 - 4.3e-08 32.5 0.1 2.1e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 UBA-like domain CAF-1_p150 PF11600.3 EKG12421.1 - 0.00037 19.9 11.8 0.00061 19.2 8.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1682 PF07946.9 EKG12421.1 - 0.41 9.4 7.1 0.74 8.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Spore_coat_CotO PF14153.1 EKG12421.1 - 0.74 9.2 8.3 1.1 8.6 5.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 EKG12421.1 - 1 9.1 4.1 1.9 8.2 2.8 1.3 1 0 0 1 1 1 0 DDHD domain DDRGK PF09756.4 EKG12421.1 - 1.3 8.3 20.1 2.1 7.7 13.9 1.2 1 0 0 1 1 1 0 DDRGK domain Borrelia_P83 PF05262.6 EKG12421.1 - 9.5 4.3 15.1 13 3.8 10.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.20 EKG12422.1 - 0.00011 21.4 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.1 EKG12423.1 - 0.0069 16.0 0.4 0.44 10.2 0.2 2.6 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.21 EKG12423.1 - 0.0088 15.7 0.2 0.19 11.5 0.1 2.4 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.7 EKG12423.1 - 0.13 11.8 1.5 0.61 9.7 0.1 2.5 2 0 0 2 2 2 0 PAN-like domain PqiA PF04403.8 EKG12424.1 - 0.016 14.8 1.8 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Paraquat-inducible protein A VWA PF00092.23 EKG12426.1 - 8.1e-10 38.6 0.0 2.4e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EKG12426.1 - 1.9e-07 31.3 0.0 9.3e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EKG12426.1 - 0.00037 20.3 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus FTR1 PF03239.9 EKG12428.1 - 1.4e-90 303.3 9.7 1.7e-90 303.0 6.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family SecY PF00344.15 EKG12428.1 - 0.017 14.0 3.2 0.044 12.6 0.1 2.5 3 0 0 3 3 3 0 SecY translocase Cu-oxidase_2 PF07731.9 EKG12429.1 - 6.1e-48 161.8 3.1 3.3e-40 136.7 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG12429.1 - 2.8e-46 156.0 3.3 6e-43 145.3 0.9 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG12429.1 - 3.1e-38 131.1 6.4 2.2e-33 115.4 0.6 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EKG12429.1 - 1.3e-06 28.1 0.0 0.07 13.0 0.0 4.2 4 1 0 4 4 4 2 Cupredoxin-like domain C1q PF00386.16 EKG12429.1 - 0.0046 16.9 0.1 0.67 9.9 0.1 2.8 2 0 0 2 2 2 1 C1q domain Glyoxalase PF00903.20 EKG12429.1 - 0.084 12.8 0.0 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.11 EKG12430.1 - 5.4e-29 101.0 35.3 6.3e-29 100.7 24.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EKG12430.1 - 0.35 10.6 4.5 0.16 11.7 0.2 2.6 3 0 0 3 3 3 0 MFS_1 like family Pox_P21 PF05313.7 EKG12430.1 - 0.51 9.5 2.8 0.24 10.6 0.3 1.6 2 0 0 2 2 2 0 Poxvirus P21 membrane protein SPRY PF00622.23 EKG12432.1 - 2.8e-19 69.4 0.0 4.5e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 SPRY domain HEAT_EZ PF13513.1 EKG12433.1 - 1.1e-26 92.6 16.0 5.7e-13 48.9 0.0 9.9 9 2 2 11 11 11 6 HEAT-like repeat HEAT_2 PF13646.1 EKG12433.1 - 7.1e-22 77.4 5.0 5.5e-08 32.9 0.0 7.6 4 3 5 9 9 9 8 HEAT repeats HEAT PF02985.17 EKG12433.1 - 1.1e-21 74.8 11.6 0.011 15.7 0.0 10.3 10 0 0 10 10 10 5 HEAT repeat Vac14_Fab1_bd PF12755.2 EKG12433.1 - 6.7e-13 48.8 0.4 0.038 14.3 0.0 6.2 5 2 1 6 6 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EKG12433.1 - 6.2e-10 39.2 0.2 0.0017 18.2 0.0 5.2 4 3 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EKG12433.1 - 5.1e-07 29.5 0.6 7.8e-06 25.7 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EKG12433.1 - 3.5e-06 26.5 0.2 4.2 6.6 0.0 5.6 4 2 0 5 5 5 1 CLASP N terminal Arm PF00514.18 EKG12433.1 - 1.1e-05 25.0 2.4 7.2 6.5 0.0 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EKG12433.1 - 5.6e-05 22.0 0.5 0.026 13.2 0.0 3.8 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 EKG12433.1 - 0.00041 18.8 0.9 0.054 11.8 0.0 3.5 3 2 0 4 4 4 1 Adaptin N terminal region DUF1546 PF07571.8 EKG12433.1 - 0.0025 17.8 0.0 23 5.1 0.0 4.9 5 1 1 6 6 6 0 Protein of unknown function (DUF1546) Cohesin_HEAT PF12765.2 EKG12433.1 - 0.02 14.8 0.2 9.9 6.2 0.0 4.0 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.11 EKG12433.1 - 0.065 13.7 6.7 16 6.2 0.0 5.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Zn_clus PF00172.13 EKG12434.1 - 2.4e-08 33.7 13.2 3.8e-08 33.0 9.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EKG12434.1 - 1e-06 27.6 1.0 1.7e-06 26.8 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 EKG12437.1 - 5.5e-09 35.5 1.0 0.54 10.2 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.7 EKG12437.1 - 0.061 11.1 0.0 8.8 3.9 0.0 2.7 2 1 0 3 3 3 0 IKI3 family PD40 PF07676.7 EKG12437.1 - 0.38 10.4 2.9 2.1 8.1 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat HSP70 PF00012.15 EKG12438.1 - 1.8e-11 42.7 0.3 9.8e-10 36.9 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EKG12438.1 - 0.0038 16.8 0.1 0.0088 15.6 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EKG12438.1 - 0.072 11.6 0.1 0.3 9.6 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein HET PF06985.6 EKG12439.1 - 1.3e-17 64.2 0.0 1.9e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SRP19 PF01922.12 EKG12440.1 - 1.7e-29 102.2 0.0 2.4e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein PAH PF02671.16 EKG12440.1 - 0.051 13.1 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Paired amphipathic helix repeat Aminotran_3 PF00202.16 EKG12441.1 - 1.4e-83 280.5 0.0 1.6e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.20 EKG12442.1 - 2.6e-58 197.2 0.0 4.8e-58 196.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12442.1 - 1.8e-19 69.8 0.0 9.3e-19 67.4 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Mis12 PF05859.7 EKG12443.1 - 1.7e-29 102.4 0.0 3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein Choline_kinase PF01633.15 EKG12444.1 - 1.3e-61 207.9 0.0 4.7e-61 206.0 0.0 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EKG12444.1 - 2.1e-20 71.8 0.0 3.9e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EKG12444.1 - 1.6e-09 37.8 0.5 1.6e-09 37.8 0.4 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family APC10 PF03256.11 EKG12446.1 - 1e-28 100.2 0.0 3e-28 98.7 0.0 1.6 1 1 1 2 2 2 1 Anaphase-promoting complex, subunit 10 (APC10) KdpC PF02669.10 EKG12447.1 - 4.5 6.9 5.4 0.76 9.4 1.1 1.6 2 0 0 2 2 2 0 K+-transporting ATPase, c chain ELO PF01151.13 EKG12448.1 - 6.3e-89 297.5 1.5 7.7e-89 297.2 1.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ETRAMP PF09716.5 EKG12448.1 - 0.8 9.7 5.2 9.8 6.2 0.0 3.5 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) RCC1 PF00415.13 EKG12449.1 - 3.2e-33 113.6 2.5 1e-06 28.8 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKG12449.1 - 1.9e-13 49.6 13.0 3.4e-09 36.0 0.0 6.1 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 EKG12450.1 - 2.6e-31 108.4 1.2 6.2e-31 107.2 0.4 1.9 2 0 0 2 2 2 1 Sec34-like family Fig1 PF12351.3 EKG12451.1 - 1.4e-57 194.5 5.4 1.4e-57 194.5 3.7 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EKG12451.1 - 3.7e-11 42.9 4.6 5.7e-11 42.3 3.2 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EKG12451.1 - 0.084 11.7 15.7 0.0067 15.3 6.1 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EKG12451.1 - 0.44 10.7 11.7 0.38 10.9 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 EKG12451.1 - 0.87 9.8 5.8 0.61 10.3 1.5 2.5 2 0 0 2 2 2 0 MltD lipid attachment motif Amastin PF07344.6 EKG12451.1 - 2 8.0 8.2 12 5.4 3.5 2.4 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF4131 PF13567.1 EKG12451.1 - 8.3 5.7 18.2 0.17 11.2 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) HSP9_HSP12 PF04119.7 EKG12452.1 - 5.9e-28 96.7 9.4 5.9e-28 96.7 6.5 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 Crystall PF00030.14 EKG12454.1 - 0.073 12.9 0.4 0.12 12.2 0.3 1.5 1 1 0 1 1 1 0 Beta/Gamma crystallin Tannase PF07519.6 EKG12455.1 - 1.1e-52 179.3 0.1 9.7e-52 176.2 0.1 1.9 1 1 0 1 1 1 1 Tannase and feruloyl esterase eIF_4EBP PF05456.6 EKG12456.1 - 0.096 12.3 0.4 1.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) ADH_zinc_N PF00107.21 EKG12458.1 - 6.5e-21 74.2 0.1 9.8e-21 73.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG12458.1 - 5.3e-05 24.1 0.0 0.00014 22.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase VWA_3 PF13768.1 EKG12460.1 - 1.7e-26 92.7 0.0 2.9e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EKG12460.1 - 1.2e-18 66.8 0.0 3.4e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EKG12460.1 - 1.5e-11 44.7 0.0 2.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EKG12460.1 - 3.8e-10 39.0 0.0 8.6e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EKG12460.1 - 2.4e-08 33.9 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EKG12460.1 - 0.0044 16.2 0.0 0.024 13.7 0.0 2.0 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Glyco_trans_2_3 PF13632.1 EKG12461.1 - 5.1e-45 153.5 0.8 1.3e-44 152.2 0.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG12461.1 - 7.9e-09 35.6 0.0 1.2e-07 31.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EKG12461.1 - 1.1e-06 28.4 0.0 1.9e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EKG12461.1 - 0.012 14.8 0.0 0.071 12.3 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferase family 21 Ceramidase_alk PF04734.8 EKG12463.1 - 1.1e-283 942.2 0.0 1.2e-283 942.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 EKG12464.1 - 8.6e-45 152.9 0.0 9.4e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 EKG12464.1 - 0.027 14.2 4.0 0.038 13.7 2.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding cNMP_binding PF00027.24 EKG12465.1 - 4.2e-43 145.0 0.0 6.7e-22 77.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EKG12465.1 - 3.2e-11 42.4 0.6 6.4e-11 41.4 0.4 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit GXGXG PF01493.14 EKG12465.1 - 0.1 11.5 0.0 0.99 8.3 0.0 2.0 2 0 0 2 2 2 0 GXGXG motif Crystall PF00030.14 EKG12466.1 - 0.0011 18.7 0.0 0.074 12.9 0.0 2.0 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 EKG12466.1 - 0.07 12.8 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Beta/Gamma crystallin PseudoU_synth_1 PF01416.15 EKG12467.1 - 7.4e-29 100.2 0.0 2.9e-20 72.6 0.0 3.7 3 2 0 3 3 3 2 tRNA pseudouridine synthase INO80_Ies4 PF08193.6 EKG12467.1 - 0.017 15.0 4.8 0.03 14.2 0.2 2.3 2 0 0 2 2 2 0 INO80 complex subunit Ies4 DUF2360 PF10152.4 EKG12467.1 - 0.072 13.3 0.9 0.57 10.4 0.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) ubiquitin PF00240.18 EKG12468.1 - 3.1e-05 23.2 0.0 4.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EKG12468.1 - 0.028 14.9 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD vATP-synt_AC39 PF01992.11 EKG12470.1 - 1.3e-116 389.4 0.0 1.5e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit YopE_N PF09020.5 EKG12470.1 - 0.12 12.3 0.6 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 YopE, N terminal Ras PF00071.17 EKG12471.1 - 3e-15 55.9 0.0 6.5e-12 45.1 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EKG12471.1 - 6.8e-08 33.0 0.0 1.7e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG12471.1 - 0.0065 15.7 0.0 0.93 8.7 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKG12471.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EKG12471.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1399 PF07173.7 EKG12472.1 - 1.6e-13 51.1 0.3 5.7e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) DUF1215 PF06744.7 EKG12472.1 - 0.089 12.4 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) Tannase PF07519.6 EKG12473.1 - 3.2e-118 395.4 1.3 4.3e-118 395.0 0.9 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EKG12473.1 - 0.023 14.2 0.0 0.072 12.6 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pribosyl_synth PF14572.1 EKG12476.1 - 3.8e-40 137.5 2.7 9.4e-35 120.0 0.9 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EKG12476.1 - 1.8e-34 117.9 0.0 6.2e-34 116.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EKG12476.1 - 5.5e-14 51.9 0.5 1.7e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EKG12476.1 - 0.00012 21.3 0.2 0.00018 20.7 0.2 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Herpes_LMP2 PF07415.6 EKG12476.1 - 0.84 8.1 2.9 1.1 7.7 2.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Lactamase_B PF00753.22 EKG12477.1 - 4e-05 23.3 4.6 0.00028 20.5 3.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG12477.1 - 9e-05 22.0 0.0 0.00015 21.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Trehalase PF01204.13 EKG12478.1 - 1.7e-192 640.6 0.4 2e-192 640.4 0.3 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EKG12478.1 - 1.2e-17 62.8 0.3 2e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 EKG12478.1 - 0.05 13.4 0.0 6 6.8 0.0 2.7 3 0 0 3 3 3 0 Ribbon-helix-helix domain MBF1 PF08523.5 EKG12479.1 - 9.8e-26 89.5 1.6 2.2e-25 88.4 1.1 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EKG12479.1 - 7e-09 35.3 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EKG12479.1 - 0.00063 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EKG12479.1 - 0.0064 16.5 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Opy2 PF09463.5 EKG12480.1 - 3.8e-10 39.6 21.1 5.9e-10 39.0 14.6 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 EKG12480.1 - 0.22 11.2 0.4 0.44 10.2 0.3 1.4 1 0 0 1 1 1 0 Syndecan domain Pyridoxal_deC PF00282.14 EKG12482.1 - 1.7e-77 260.3 0.0 2.3e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.15 EKG12482.1 - 0.027 13.0 0.0 0.044 12.3 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fungal_trans PF04082.13 EKG12483.1 - 1e-22 80.3 0.0 1.8e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG12483.1 - 3.4e-05 23.6 8.6 6.5e-05 22.7 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HR1 PF02185.11 EKG12483.1 - 3.4 7.4 6.7 0.21 11.3 0.6 2.0 2 0 0 2 2 2 0 Hr1 repeat A_deaminase PF00962.17 EKG12484.1 - 3.6e-22 78.7 0.0 4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Fungal_trans PF04082.13 EKG12486.1 - 3.2e-13 49.1 2.5 3.2e-13 49.1 1.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG12486.1 - 1.5e-05 24.8 9.3 1.5e-05 24.8 6.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EKG12487.1 - 2.7e-23 82.6 0.0 4.4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG12487.1 - 2.9e-05 23.1 0.3 0.038 12.8 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EKG12487.1 - 0.0021 17.1 0.1 0.59 9.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKG12487.1 - 0.015 15.2 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG12487.1 - 0.021 15.2 0.3 0.35 11.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EKG12488.1 - 4.9e-33 114.3 80.2 9.7e-26 90.2 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ost4 PF10215.4 EKG12488.1 - 0.79 9.2 3.6 2.3 7.7 0.1 2.8 2 0 0 2 2 2 0 Oligosaccaryltransferase Matrilin_ccoil PF10393.4 EKG12489.1 - 0.17 11.2 0.7 0.63 9.4 0.0 2.0 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Pec_lyase_C PF00544.14 EKG12490.1 - 2.2e-52 177.4 5.8 2.9e-52 177.0 4.0 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EKG12490.1 - 7.6e-07 29.0 11.6 1.3e-05 25.0 8.0 2.3 1 1 0 1 1 1 1 Right handed beta helix region DIM PF08194.7 EKG12490.1 - 0.57 10.1 2.1 1.2 9.1 1.4 1.5 1 0 0 1 1 1 0 DIM protein MFS_1 PF07690.11 EKG12491.1 - 1.1e-29 103.3 24.1 1.4e-29 102.9 16.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12491.1 - 3.3e-17 62.2 5.8 4.5e-17 61.7 4.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EKG12491.1 - 0.0011 17.2 2.2 0.0015 16.8 1.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Orn_Arg_deC_N PF02784.11 EKG12492.1 - 4.5e-37 127.5 0.0 5.6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EKG12492.1 - 4.1e-21 74.8 0.0 5.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EKG12492.1 - 0.0017 17.6 0.0 0.0025 17.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HET PF06985.6 EKG12493.1 - 3.3e-24 85.6 0.3 5.7e-24 84.8 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EKG12494.1 - 2.1e-16 59.4 0.1 2.6e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG12495.1 - 4.1e-12 45.3 0.0 5.4e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N_2 PF13602.1 EKG12496.1 - 1.9e-27 96.6 1.3 4.3e-27 95.5 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EKG12496.1 - 5.1e-12 45.4 2.6 5.1e-12 45.4 1.8 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG12496.1 - 0.0017 18.0 0.0 0.0049 16.6 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EKG12496.1 - 0.042 13.8 0.2 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding PP2C PF00481.16 EKG12497.1 - 3.1e-33 115.2 0.0 5e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EKG12497.1 - 0.082 12.5 0.1 9.2 5.9 0.0 3.7 4 1 1 5 5 5 0 Stage II sporulation protein E (SpoIIE) DUF2407 PF10302.4 EKG12498.1 - 2.5e-05 24.3 0.0 0.0001 22.4 0.0 2.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EKG12498.1 - 0.00093 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EKG12498.1 - 0.002 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.10 EKG12500.1 - 4.8e-23 81.5 0.0 9.1e-23 80.6 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase MIF PF01187.13 EKG12501.1 - 2e-09 37.5 0.0 3.1e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) CENP-X PF09415.5 EKG12502.1 - 4.9e-25 87.1 0.0 7.6e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Histone PF00125.19 EKG12502.1 - 0.042 13.9 0.1 0.072 13.2 0.1 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 IER PF05760.7 EKG12502.1 - 0.27 11.1 3.3 0.31 10.9 2.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Copper-bind PF00127.15 EKG12503.1 - 9.9e-05 22.5 0.2 0.00017 21.7 0.2 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EKG12503.1 - 0.016 15.0 0.5 0.052 13.3 0.4 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain ketoacyl-synt PF00109.21 EKG12504.1 - 1.3e-291 961.8 31.4 1e-74 251.2 1.6 6.1 6 0 0 6 6 6 4 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG12504.1 - 3.5e-179 590.5 34.0 1.9e-52 177.5 1.9 6.3 5 0 0 5 5 5 4 KR domain Ketoacyl-synt_C PF02801.17 EKG12504.1 - 7.7e-158 516.1 9.8 5.6e-40 135.8 0.0 5.1 4 0 0 4 4 4 4 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EKG12504.1 - 3.9e-155 511.6 56.2 1.8e-44 151.6 1.0 8.2 8 0 0 8 8 7 4 short chain dehydrogenase PS-DH PF14765.1 EKG12504.1 - 4.4e-101 337.9 18.5 7.5e-37 127.0 1.5 3.9 3 0 0 3 3 3 3 Polyketide synthase dehydratase PP-binding PF00550.20 EKG12504.1 - 6.3e-81 266.6 5.0 7.1e-12 45.4 0.0 9.0 8 0 0 8 8 8 8 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EKG12504.1 - 8.2e-54 180.1 0.0 4.9e-17 62.2 0.0 4.0 3 0 0 3 3 3 3 Methyltransferase domain Methyltransf_23 PF13489.1 EKG12504.1 - 9.1e-36 122.9 0.0 3.5e-11 43.0 0.0 3.6 3 0 0 3 3 3 3 Methyltransferase domain Methyltransf_11 PF08241.7 EKG12504.1 - 1.3e-32 112.1 0.0 2.5e-10 40.6 0.0 4.1 3 0 0 3 3 3 3 Methyltransferase domain ADH_zinc_N PF00107.21 EKG12504.1 - 1.8e-32 111.6 0.5 4.6e-16 58.5 0.0 3.1 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EKG12504.1 - 3.5e-31 107.8 0.0 1.4e-11 44.1 0.0 3.6 3 0 0 3 3 3 3 Methyltransferase domain Acyl_transf_1 PF00698.16 EKG12504.1 - 6.4e-29 101.2 0.0 3.9e-16 59.2 0.0 2.5 1 1 1 2 2 2 2 Acyl transferase domain ADH_zinc_N_2 PF13602.1 EKG12504.1 - 2.2e-22 80.3 3.9 4.5e-12 46.9 0.9 5.6 4 0 0 4 4 4 2 Zinc-binding dehydrogenase Epimerase PF01370.16 EKG12504.1 - 4.3e-16 59.0 6.4 1.4e-05 24.6 0.0 5.4 5 0 0 5 5 5 3 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EKG12504.1 - 9.8e-14 50.9 9.9 0.00052 19.0 0.0 4.6 4 0 0 4 4 4 4 Thiolase, N-terminal domain ADH_N PF08240.7 EKG12504.1 - 1.5e-12 47.2 1.8 3.1e-06 26.8 0.0 3.0 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EKG12504.1 - 2.9e-12 46.1 0.0 0.002 17.2 0.0 3.6 3 0 0 3 3 3 3 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 EKG12504.1 - 1.6e-10 40.9 0.0 0.00037 20.0 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF938) DREV PF05219.7 EKG12504.1 - 4.5e-08 32.3 0.0 0.0037 16.1 0.0 3.4 3 1 0 3 3 3 2 DREV methyltransferase Polysacc_synt_2 PF02719.10 EKG12504.1 - 2.4e-07 29.9 0.0 0.00075 18.4 0.0 3.1 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein ACP_syn_III PF08545.5 EKG12504.1 - 6.6e-07 28.9 30.0 0.0037 16.8 1.1 6.9 6 2 0 6 6 5 3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RrnaAD PF00398.15 EKG12504.1 - 1.2e-05 24.4 0.0 0.39 9.7 0.0 3.2 3 0 0 3 3 3 2 Ribosomal RNA adenine dimethylase NAD_binding_10 PF13460.1 EKG12504.1 - 1.4e-05 25.1 30.6 0.0026 17.7 1.2 7.2 7 0 0 7 7 6 2 NADH(P)-binding NodS PF05401.6 EKG12504.1 - 2.3e-05 23.8 0.0 0.91 8.8 0.0 3.6 3 0 0 3 3 3 2 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EKG12504.1 - 0.00014 21.3 0.0 0.065 12.6 0.0 3.2 3 0 0 3 3 3 1 Putative methyltransferase ELFV_dehydrog PF00208.16 EKG12504.1 - 0.027 14.0 5.8 21 4.6 0.0 5.2 6 0 0 6 6 6 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Methyltransf_8 PF05148.10 EKG12504.1 - 0.038 13.6 0.0 0.68 9.5 0.0 3.0 4 0 0 4 4 3 0 Hypothetical methyltransferase NAD_binding_4 PF07993.7 EKG12504.1 - 0.056 12.3 0.9 0.49 9.2 0.1 2.4 2 0 0 2 2 2 0 Male sterility protein NNMT_PNMT_TEMT PF01234.12 EKG12504.1 - 0.075 11.9 0.1 14 4.5 0.0 3.2 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family DNA_gyraseB_C PF00986.16 EKG12504.1 - 0.16 11.7 0.5 20 5.0 0.0 3.3 3 0 0 3 3 2 0 DNA gyrase B subunit, carboxyl terminus AlaDh_PNT_C PF01262.16 EKG12504.1 - 0.3 10.6 6.9 0.075 12.5 0.0 3.1 3 0 0 3 3 2 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_28 PF02636.12 EKG12504.1 - 0.36 10.1 0.0 33 3.7 0.0 3.1 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 EKG12504.1 - 0.37 10.2 0.1 33 3.9 0.0 3.2 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EKG12504.1 - 0.88 8.2 0.0 10 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Fibrillarin PF01269.12 EKG12504.1 - 2.6 6.8 0.2 10 4.9 0.0 2.0 2 0 0 2 2 2 0 Fibrillarin UBA_3 PF09288.5 EKG12504.1 - 3.3 7.3 0.0 14 5.4 0.0 2.0 2 0 0 2 2 1 0 Fungal ubiquitin-associated domain PPP4R2 PF09184.6 EKG12504.1 - 5.6 6.4 1.4 9.9 5.6 1.0 1.3 1 0 0 1 1 1 0 PPP4R2 Helicase_Sgs1 PF11408.3 EKG12504.1 - 6.4 6.6 0.0 20 5.1 0.0 1.8 1 0 0 1 1 1 0 Sgs1 RecQ helicase FAE1_CUT1_RppA PF08392.7 EKG12504.1 - 6.4 5.7 12.0 4.1 6.3 0.2 4.0 4 0 0 4 4 4 0 FAE1/Type III polyketide synthase-like protein DUF869 PF05911.6 EKG12504.1 - 9 4.3 0.0 15 3.6 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) ketoacyl-synt PF00109.21 EKG12505.1 - 8.8e-152 503.7 12.8 3.2e-78 262.7 1.3 3.0 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG12505.1 - 2.6e-74 246.6 4.7 5.2e-40 136.0 0.1 2.8 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EKG12505.1 - 2.5e-53 181.4 0.3 5.2e-53 180.4 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EKG12505.1 - 2.1e-43 148.0 2.4 6e-43 146.6 1.7 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKG12505.1 - 4e-40 137.4 2.3 4e-40 137.4 1.6 2.5 3 0 0 3 3 3 1 short chain dehydrogenase PP-binding PF00550.20 EKG12505.1 - 5e-22 77.9 0.3 8.1e-11 42.0 0.0 3.4 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EKG12505.1 - 7.7e-20 71.2 2.6 2.6e-14 53.0 0.5 2.5 2 0 0 2 2 2 2 Polyketide synthase dehydratase Thiolase_N PF00108.18 EKG12505.1 - 1.8e-12 46.7 4.3 5.7e-06 25.5 0.1 2.5 2 0 0 2 2 2 2 Thiolase, N-terminal domain Epimerase PF01370.16 EKG12505.1 - 0.00074 19.0 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ACP_syn_III PF08545.5 EKG12505.1 - 0.028 14.0 9.3 0.064 12.9 0.2 3.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Polysacc_synt_2 PF02719.10 EKG12505.1 - 0.041 12.7 0.1 0.14 11.0 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ketoacyl-synt PF00109.21 EKG12506.1 - 1.7e-152 506.0 11.0 5.9e-77 258.5 0.1 4.2 5 0 0 5 5 4 2 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG12506.1 - 4.9e-101 335.8 23.9 5.9e-52 175.9 1.9 5.3 5 1 0 5 5 5 2 KR domain adh_short PF00106.20 EKG12506.1 - 5.3e-84 280.1 32.1 1e-44 152.3 2.5 6.4 7 0 0 7 7 6 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG12506.1 - 2.4e-75 250.0 0.8 3.8e-38 129.9 0.0 2.9 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EKG12506.1 - 6.1e-72 242.2 16.0 8.1e-40 136.8 6.0 2.6 2 0 0 2 2 2 2 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EKG12506.1 - 5.3e-48 161.5 0.0 5.9e-15 55.5 0.0 4.2 3 0 0 3 3 3 3 Methyltransferase domain Acyl_transf_1 PF00698.16 EKG12506.1 - 4.2e-41 141.3 1.1 9e-41 140.2 0.7 1.5 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_23 PF13489.1 EKG12506.1 - 4e-35 120.9 0.0 8.3e-12 45.1 0.0 4.3 4 0 0 4 4 4 3 Methyltransferase domain Methyltransf_31 PF13847.1 EKG12506.1 - 8.8e-24 83.8 0.0 3.8e-07 29.8 0.0 3.5 3 0 0 3 3 3 3 Methyltransferase domain PP-binding PF00550.20 EKG12506.1 - 1.2e-21 76.7 0.1 2.1e-12 47.0 0.0 4.2 4 0 0 4 4 3 2 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EKG12506.1 - 2.8e-21 76.1 0.1 9e-05 23.0 0.0 5.5 5 0 0 5 5 4 3 Methyltransferase domain Methyltransf_11 PF08241.7 EKG12506.1 - 3.6e-21 75.4 0.8 9.9e-07 29.1 0.0 4.6 5 0 0 5 5 3 3 Methyltransferase domain ADH_zinc_N PF00107.21 EKG12506.1 - 6.7e-16 58.0 0.3 6.2e-15 54.8 0.0 3.0 3 0 0 3 3 1 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 EKG12506.1 - 2.1e-10 40.3 0.0 0.00057 19.3 0.0 3.4 3 0 0 3 3 3 2 Putative methyltransferase ADH_zinc_N_2 PF13602.1 EKG12506.1 - 5.5e-10 40.2 0.0 8.5e-09 36.3 0.0 3.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EKG12506.1 - 2.9e-09 36.2 3.3 0.00027 20.0 0.1 2.7 2 0 0 2 2 2 2 Thiolase, N-terminal domain DUF938 PF06080.7 EKG12506.1 - 4.8e-08 32.7 0.0 0.085 12.3 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF938) ADH_N PF08240.7 EKG12506.1 - 7.8e-07 28.8 2.4 1.8e-06 27.6 0.3 2.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thioesterase PF00975.15 EKG12506.1 - 1.6e-06 28.5 0.0 4.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain adh_short_C2 PF13561.1 EKG12506.1 - 1.7e-06 28.0 0.1 0.029 14.1 0.0 3.0 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Methyltransf_28 PF02636.12 EKG12506.1 - 9.9e-06 25.1 0.0 2.1 7.6 0.0 3.4 3 0 0 3 3 3 2 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 EKG12506.1 - 1.5e-05 24.5 0.0 0.0026 17.1 0.0 3.1 3 0 0 3 3 3 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EKG12506.1 - 0.0023 17.0 0.0 0.87 8.5 0.0 2.7 3 0 0 3 3 3 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EKG12506.1 - 0.0041 16.0 0.0 5.1 5.8 0.0 3.3 3 0 0 3 3 3 1 DREV methyltransferase ATG16 PF08614.6 EKG12506.1 - 0.055 13.2 0.4 1.2 8.9 0.4 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PCMT PF01135.14 EKG12506.1 - 0.21 11.0 0.1 43 3.5 0.0 3.2 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Polysacc_synt_2 PF02719.10 EKG12506.1 - 0.29 9.9 0.0 13 4.5 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DNA_gyraseB_C PF00986.16 EKG12506.1 - 1.2 8.9 0.1 6.3 6.6 0.0 2.1 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus DUF2340 PF10209.4 EKG12506.1 - 1.4 9.1 0.0 2.9 8.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) p450 PF00067.17 EKG12507.1 - 1.6e-63 214.8 0.0 2.1e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3692 PF12469.3 EKG12507.1 - 0.069 13.3 0.0 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 CRISPR-associated protein MFS_1 PF07690.11 EKG12508.1 - 5.5e-31 107.5 34.5 1.5e-23 83.1 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12508.1 - 1.5e-05 23.8 9.2 0.0013 17.4 0.0 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.15 EKG12508.1 - 0.11 10.5 4.6 0.97 7.4 0.8 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MaoC_dehydrat_N PF13452.1 EKG12509.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Renin_r PF07850.9 EKG12510.1 - 0.16 12.3 0.5 8.7 6.7 0.0 2.3 1 1 1 2 2 2 0 Renin receptor-like protein PBP PF01161.15 EKG12512.1 - 0.11 12.2 0.4 0.16 11.7 0.3 1.2 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein F-box PF00646.28 EKG12515.1 - 0.0036 16.9 0.0 0.0087 15.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKG12515.1 - 0.0082 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like DHDPS PF00701.17 EKG12515.1 - 0.13 10.8 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family DUF2347 PF09804.4 EKG12516.1 - 2.5e-93 312.3 0.0 3.6e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EKG12516.1 - 1.4e-41 142.5 0.9 1.4e-41 142.5 0.6 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EKG12516.1 - 0.00037 19.0 0.0 0.25 9.7 0.0 2.5 2 1 0 2 2 2 2 Transport protein Avl9 SPA PF08616.5 EKG12516.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.7 1 1 0 1 1 1 0 Stabilization of polarity axis GFA PF04828.9 EKG12517.1 - 1.3e-22 79.5 0.3 1.7e-22 79.1 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EKG12517.1 - 0.079 12.7 0.8 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon Cys_knot PF00007.17 EKG12517.1 - 0.17 11.9 3.7 1.4 9.0 0.8 2.3 2 1 0 2 2 2 0 Cystine-knot domain Penaeidin PF05927.6 EKG12517.1 - 0.85 10.2 4.5 0.59 10.7 1.5 1.8 2 0 0 2 2 2 0 Penaeidin Vps39_2 PF10367.4 EKG12518.1 - 7.2e-08 32.5 0.0 2e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EKG12518.1 - 0.001 18.6 0.2 0.018 14.6 0.0 2.6 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.4 EKG12518.1 - 0.0013 18.6 0.2 0.35 10.8 0.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Turandot PF07240.6 EKG12518.1 - 0.025 14.0 0.0 0.63 9.5 0.0 2.6 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot CASP_C PF08172.7 EKG12519.1 - 3.1e-89 298.2 1.2 3.1e-89 298.2 0.8 3.9 3 1 0 3 3 3 2 CASP C terminal TMF_DNA_bd PF12329.3 EKG12519.1 - 0.0065 16.2 5.1 0.0065 16.2 3.5 7.1 7 0 0 7 7 7 2 TATA element modulatory factor 1 DNA binding Mago_nashi PF02792.9 EKG12519.1 - 0.02 14.5 0.6 0.02 14.5 0.4 2.4 2 0 0 2 2 2 0 Mago nashi protein DUF904 PF06005.7 EKG12519.1 - 0.049 13.9 0.4 0.049 13.9 0.3 7.2 4 2 1 5 5 5 0 Protein of unknown function (DUF904) TPR_MLP1_2 PF07926.7 EKG12519.1 - 6.8 6.4 69.2 1.6 8.4 6.6 6.6 5 1 1 6 6 6 0 TPR/MLP1/MLP2-like protein DUF3455 PF11937.3 EKG12520.1 - 7.6e-41 139.9 4.7 1.3e-40 139.2 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) PIGA PF08288.7 EKG12521.1 - 3.6e-47 158.6 3.2 7.5e-47 157.6 0.9 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EKG12521.1 - 3.1e-29 101.5 0.0 4.4e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EKG12521.1 - 2.7e-17 63.1 0.0 4.8e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EKG12521.1 - 4.4e-17 62.3 0.7 9.3e-17 61.2 0.5 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EKG12521.1 - 4.9e-14 52.7 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EKG12521.1 - 8.7e-06 25.6 0.4 2.8e-05 23.9 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EKG12521.1 - 0.0031 17.7 0.0 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Mito_fiss_reg PF05308.6 EKG12522.1 - 0.52 9.6 6.3 0.65 9.3 4.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Helicase_C PF00271.26 EKG12523.1 - 4.8e-19 68.0 0.1 9.4e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG12523.1 - 4.9e-16 58.6 0.0 8.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1253 PF06862.7 EKG12523.1 - 0.0019 16.6 0.0 0.25 9.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) CDC45 PF02724.9 EKG12523.1 - 0.011 13.7 1.4 0.016 13.3 1.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EKG12523.1 - 1.4 6.7 12.3 0.35 8.7 6.4 1.4 2 0 0 2 2 2 0 Nop14-like family Macoilin PF09726.4 EKG12523.1 - 2.6 6.2 10.6 3.5 5.8 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3827 PF12877.2 EKG12523.1 - 5.9 4.8 10.6 8.3 4.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Asp PF00026.18 EKG12524.1 - 2.5e-66 224.1 9.1 3e-66 223.8 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG12524.1 - 1.9e-06 28.2 0.7 0.00072 20.0 0.2 2.9 2 1 0 2 2 2 2 Aspartyl protease Pkinase PF00069.20 EKG12525.1 - 4.6e-47 160.3 0.0 3.3e-44 150.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12525.1 - 6.3e-30 104.1 0.0 1.1e-28 100.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG12525.1 - 0.00056 18.9 0.0 0.00089 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EKG12525.1 - 0.0016 17.3 0.1 0.0024 16.7 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EKG12525.1 - 0.089 11.5 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EKG12525.1 - 0.13 12.0 0.4 0.42 10.3 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mem_trans PF03547.13 EKG12526.1 - 7.3e-54 182.5 0.2 9.1e-54 182.2 0.1 1.1 1 0 0 1 1 1 1 Membrane transport protein DDRGK PF09756.4 EKG12528.1 - 0.34 10.2 11.6 0.58 9.5 8.0 1.3 1 0 0 1 1 1 0 DDRGK domain Prothymosin PF03247.9 EKG12528.1 - 1.4 9.0 36.8 0.036 14.2 17.5 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family BTV_NS2 PF04514.7 EKG12528.1 - 3 6.6 11.7 5.5 5.7 8.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Med17 PF10156.4 EKG12528.1 - 3 5.9 8.3 5.3 5.2 5.7 1.3 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF2256 PF10013.4 EKG12528.1 - 3.7 7.3 4.8 2 8.2 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) RR_TM4-6 PF06459.7 EKG12528.1 - 5.7 6.7 14.0 2.2 8.1 5.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.7 EKG12528.1 - 6.7 5.8 22.6 1.7 7.8 11.1 2.0 2 0 0 2 2 2 0 SDA1 DUF1510 PF07423.6 EKG12528.1 - 8 5.7 19.0 0.21 10.9 7.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EKG12528.1 - 9.1 4.0 27.7 3.2 5.5 13.7 2.0 2 0 0 2 2 2 0 Nop14-like family Fibrillarin PF01269.12 EKG12529.1 - 1.4e-107 357.8 0.0 1.9e-107 357.4 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EKG12529.1 - 7.3e-07 28.9 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EKG12529.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EKG12529.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L22 PF00237.14 EKG12530.1 - 1.4e-36 124.5 0.1 2.6e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e His_Phos_1 PF00300.17 EKG12531.1 - 3.8e-18 66.0 0.0 5.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_S8 PF00410.14 EKG12532.1 - 1.3e-25 89.7 0.0 1.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 MARVEL PF01284.18 EKG12534.1 - 1.5e-17 63.7 10.8 2.1e-17 63.3 7.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Scs3p PF10261.4 EKG12534.1 - 0.024 13.6 2.2 0.22 10.5 0.9 2.0 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF3816 PF12822.2 EKG12534.1 - 0.046 13.6 1.9 0.058 13.2 1.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF588 PF04535.7 EKG12534.1 - 8.4 5.9 7.8 1.1 8.7 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF588) HATPase_c PF02518.21 EKG12536.1 - 2.7e-20 72.1 0.0 4.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG12536.1 - 7.4e-17 61.3 0.0 1.5e-14 53.9 0.0 2.9 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EKG12536.1 - 3.3e-14 52.6 0.0 8.5e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF572 PF04502.8 EKG12536.1 - 0.0045 16.2 11.0 0.008 15.4 7.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) HATPase_c_2 PF13581.1 EKG12536.1 - 0.066 13.0 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain COesterase PF00135.23 EKG12539.1 - 1e-23 83.8 0.0 1.1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family FAD_binding_3 PF01494.14 EKG12541.1 - 1.2e-28 100.1 0.1 8.6e-15 54.6 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EKG12541.1 - 4.4e-05 22.5 3.3 0.42 9.4 0.2 3.1 3 0 0 3 3 3 3 Lycopene cyclase protein DAO PF01266.19 EKG12541.1 - 0.00043 19.3 7.9 0.0096 14.8 0.8 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EKG12541.1 - 0.0013 18.4 0.1 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 EKG12541.1 - 0.0013 18.6 0.5 0.0034 17.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG12541.1 - 0.006 16.4 0.6 0.02 14.7 0.4 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG12541.1 - 0.0085 16.1 0.2 0.026 14.6 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG12541.1 - 0.019 13.8 0.8 0.031 13.1 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.10 EKG12541.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 EKG12541.1 - 0.035 12.9 1.4 0.055 12.3 0.6 1.6 1 1 1 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EKG12541.1 - 0.037 13.0 2.9 0.029 13.4 1.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EKG12541.1 - 0.038 13.6 0.6 0.069 12.7 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-ph_phosp PF04029.9 EKG12541.1 - 0.071 12.0 0.0 0.82 8.5 0.0 2.0 2 0 0 2 2 2 0 2-phosphosulpholactate phosphatase Pyr_redox PF00070.22 EKG12541.1 - 0.14 12.5 0.5 1.3 9.5 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EKG12541.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HET PF06985.6 EKG12542.1 - 1.2e-19 70.8 0.9 3.7e-19 69.2 0.2 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 EKG12545.1 - 1.8e-09 37.8 0.4 2.1e-09 37.6 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG12545.1 - 5.7e-06 26.1 0.2 6.6e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Bac_rhamnosid_N PF08531.5 EKG12546.1 - 9.7e-47 158.6 0.0 1.8e-46 157.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.6 EKG12546.1 - 1.3e-17 63.2 0.0 1.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF4307 PF14155.1 EKG12546.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) Sugar_tr PF00083.19 EKG12548.1 - 2e-59 201.3 11.9 2.3e-59 201.1 8.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG12548.1 - 4.6e-18 65.0 27.6 1.3e-13 50.3 6.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG12548.1 - 0.033 12.3 5.4 0.69 8.0 0.1 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.14 EKG12549.1 - 1.1e-26 93.7 0.0 2.1e-26 92.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG12549.1 - 0.00036 20.4 0.2 0.0019 18.2 0.1 2.3 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG12549.1 - 0.006 15.5 1.3 1.5 7.6 0.5 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG12549.1 - 0.052 13.9 3.9 0.26 11.7 0.3 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EKG12549.1 - 0.085 11.9 2.5 0.54 9.2 0.1 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 EKG12549.1 - 0.12 11.4 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EKG12549.1 - 0.15 11.9 0.1 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Polyketide_cyc2 PF10604.4 EKG12552.1 - 3.6e-06 27.1 0.3 4.5e-06 26.8 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HSP20 PF00011.16 EKG12553.1 - 7e-13 48.3 0.2 1.1e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family NACHT PF05729.7 EKG12555.1 - 0.001 18.7 0.1 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EKG12555.1 - 0.0047 16.6 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EKG12555.1 - 0.012 15.6 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EKG12555.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKG12555.1 - 0.053 13.4 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EKG12555.1 - 0.064 12.0 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain FGase PF05013.7 EKG12557.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase DUF3339 PF11820.3 EKG12557.1 - 0.18 12.1 3.7 4.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3339) Glyco_hydro_1 PF00232.13 EKG12558.1 - 1.4e-112 376.1 2.0 2e-112 375.6 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 zf-C2H2 PF00096.21 EKG12559.1 - 5.8e-07 29.4 7.7 0.0078 16.4 1.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG12559.1 - 6.4e-05 23.0 14.2 0.0076 16.5 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG12559.1 - 0.00012 22.2 2.6 0.00012 22.2 1.8 2.4 3 0 0 3 3 3 1 Zinc-finger double domain FAM70 PF14967.1 EKG12561.1 - 0.35 10.0 1.4 0.32 10.1 0.3 1.4 2 0 0 2 2 2 0 FAM70 protein GET2 PF08690.5 EKG12561.1 - 7.9 5.6 7.7 12 5.0 5.3 1.4 1 1 0 1 1 1 0 GET complex subunit GET2 CAF-1_p150 PF11600.3 EKG12562.1 - 6e-05 22.5 34.0 6e-05 22.5 23.5 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 EKG12562.1 - 8 5.7 20.9 25 4.1 14.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TBPIP PF07106.8 EKG12564.1 - 0.013 15.0 0.3 0.013 15.0 0.2 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SUI1 PF01253.17 EKG12568.1 - 1.9e-29 101.2 5.1 2.6e-29 100.8 3.6 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF520 PF04461.8 EKG12568.1 - 0.1 12.4 3.5 0.12 12.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) ALO PF04030.9 EKG12569.1 - 5.9e-83 278.4 0.2 8e-83 277.9 0.1 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EKG12569.1 - 8.1e-17 60.9 0.3 1.5e-16 60.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S13 PF00416.17 EKG12572.1 - 2.2e-41 140.6 1.7 2.7e-41 140.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EKG12572.1 - 0.0032 16.0 0.0 0.0071 14.9 0.0 1.5 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EKG12572.1 - 0.074 13.0 0.5 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 HHH_6 PF14579.1 EKG12572.1 - 0.11 12.5 0.1 0.36 10.9 0.0 1.9 1 1 0 2 2 2 0 Helix-hairpin-helix motif Period_C PF12114.3 EKG12572.1 - 0.12 11.9 0.1 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Sec63 PF02889.11 EKG12573.1 - 3e-46 158.1 0.0 6.6e-46 156.9 0.0 1.5 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EKG12573.1 - 7.2e-17 60.8 0.0 2.2e-16 59.3 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1900 PF08954.6 EKG12574.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) Spectrin PF00435.16 EKG12576.1 - 0.43 10.8 6.8 3 8.1 0.1 2.6 2 0 0 2 2 2 0 Spectrin repeat DivIC PF04977.10 EKG12576.1 - 2.7 7.5 6.7 5.7 6.5 2.1 2.7 2 1 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 EKG12576.1 - 7.6 7.0 16.0 2.7 8.4 3.6 3.2 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Dicty_REP PF05086.7 EKG12577.1 - 0.079 10.7 0.0 0.092 10.4 0.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nol1_Nop2_Fmu PF01189.12 EKG12578.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 NOL1/NOP2/sun family LysM PF01476.15 EKG12579.1 - 7.3e-26 89.7 0.4 1.3e-08 34.6 0.0 3.2 3 0 0 3 3 3 3 LysM domain p450 PF00067.17 EKG12580.1 - 2.2e-67 227.6 0.0 2.6e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.17 EKG12582.1 - 1e-129 433.3 0.2 1.3e-129 433.0 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EKG12582.1 - 6.4e-10 39.1 0.3 1.1e-09 38.4 0.2 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EKG12582.1 - 0.00071 19.5 0.0 0.0068 16.3 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SBDS_C PF09377.5 EKG12583.1 - 2.6e-50 169.2 0.0 4.5e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EKG12583.1 - 1e-29 102.1 0.4 1e-29 102.1 0.3 1.7 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PBP PF01161.15 EKG12584.1 - 3.6e-19 69.0 0.0 4.6e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RAP1 PF07218.6 EKG12584.1 - 7.3 4.5 9.1 9.2 4.2 6.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) bZIP_1 PF00170.16 EKG12586.1 - 1.1e-08 34.8 15.6 1.1e-08 34.8 10.8 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EKG12586.1 - 2.8e-05 23.8 14.1 2.8e-05 23.8 9.7 2.9 3 0 0 3 3 3 1 Basic region leucine zipper Lactamase_B_4 PF13691.1 EKG12587.1 - 1.6e-22 78.7 0.0 2.9e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EKG12587.1 - 1.3e-09 37.9 0.0 1.9e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG12587.1 - 3.9e-09 36.3 0.0 2.2e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF1445 PF07286.7 EKG12587.1 - 0.043 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) Acetyltransf_1 PF00583.19 EKG12588.1 - 0.0007 19.5 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG12588.1 - 0.0064 16.6 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG12588.1 - 0.038 13.9 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.16 EKG12589.1 - 9.3e-47 158.4 0.4 1.1e-46 158.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EKG12589.1 - 2.3e-12 46.3 1.2 5.3e-07 28.6 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EKG12589.1 - 9.1e-10 38.0 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKG12589.1 - 2.6e-09 37.0 0.0 3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKG12589.1 - 4.5e-09 36.8 0.0 6e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EKG12589.1 - 3.8e-08 32.9 0.0 4.5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EKG12589.1 - 4.2e-07 29.3 0.0 5.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EKG12589.1 - 0.0066 17.2 0.1 0.0094 16.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG12589.1 - 0.018 15.3 0.3 0.025 14.9 0.2 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EKG12589.1 - 0.022 14.0 0.4 0.072 12.3 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NTPase_1 PF03266.10 EKG12589.1 - 0.034 13.8 0.1 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 NTPase PduV-EutP PF10662.4 EKG12589.1 - 0.062 12.7 0.1 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EKG12589.1 - 0.065 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.13 EKG12589.1 - 0.092 11.8 0.1 0.22 10.5 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 EKG12590.1 - 3.3e-74 250.6 35.7 3.3e-74 250.6 24.7 6.5 4 2 1 6 6 6 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EKG12590.1 - 2e-12 46.5 0.0 8.2e-06 25.4 0.0 3.4 3 0 0 3 3 3 2 Gelsolin repeat BP28CT PF08146.7 EKG12591.1 - 7.8e-41 139.3 1.9 7.8e-41 139.3 1.3 3.7 4 0 0 4 4 4 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EKG12591.1 - 4.4e-24 84.7 0.8 4.4e-24 84.7 0.5 5.8 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EKG12591.1 - 6.2e-10 39.2 25.1 0.043 14.1 0.1 7.9 6 1 0 7 7 7 4 HEAT repeats HEAT PF02985.17 EKG12591.1 - 5.8e-05 22.8 14.0 0.075 13.1 0.0 7.9 7 0 0 7 7 7 1 HEAT repeat PEP-utilisers_N PF05524.8 EKG12591.1 - 0.0035 17.1 0.5 0.0035 17.1 0.3 3.1 2 1 0 3 3 3 1 PEP-utilising enzyme, N-terminal Vac14_Fab1_bd PF12755.2 EKG12591.1 - 0.046 14.1 0.0 20 5.6 0.0 3.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EKG12591.1 - 1 9.9 28.0 1.8 9.1 0.1 9.1 7 3 3 10 10 10 0 HEAT-like repeat NRDE-2 PF08424.5 EKG12592.1 - 1.9e-75 253.7 0.2 6.9e-75 251.9 0.2 1.9 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EKG12592.1 - 0.15 12.8 6.9 43 5.1 0.1 5.1 4 1 2 6 6 6 0 Tetratricopeptide repeat DUF4360 PF14273.1 EKG12593.1 - 1.2e-09 38.0 0.0 1.4e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) PDEase_II PF02112.10 EKG12594.1 - 4.7e-47 160.5 0.0 1.5e-44 152.2 0.0 2.9 1 1 1 2 2 2 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EKG12594.1 - 1.9e-05 24.2 0.0 3.6e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain EF1G PF00647.14 EKG12595.1 - 6.7e-45 151.1 0.1 1.2e-44 150.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EKG12595.1 - 1.5e-11 44.1 0.1 3.9e-11 42.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EKG12595.1 - 3.4e-08 33.5 0.0 9.9e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EKG12595.1 - 8.3e-08 32.3 0.0 2.2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG12595.1 - 4.3e-07 29.7 0.0 1.1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG12595.1 - 1.7e-06 28.4 0.1 3.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ribosomal_S9 PF00380.14 EKG12596.1 - 1.5e-35 122.0 0.1 2.3e-35 121.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HET PF06985.6 EKG12599.1 - 0.0044 17.1 0.0 0.017 15.2 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC2_membrane PF01061.19 EKG12600.1 - 4.4e-89 297.1 62.2 7.7e-46 155.9 17.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EKG12600.1 - 1.9e-38 131.8 0.0 3e-18 66.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG12600.1 - 1.4e-37 127.4 8.9 3.1e-32 110.3 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EKG12600.1 - 3e-19 68.8 0.0 7.6e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EKG12600.1 - 7.8e-09 35.2 0.0 1.6e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EKG12600.1 - 9.9e-08 31.3 14.5 9.9e-08 31.3 10.0 3.0 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 EKG12600.1 - 2e-06 27.7 0.0 0.00034 20.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EKG12600.1 - 5.1e-05 22.7 1.1 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EKG12600.1 - 5.2e-05 23.3 1.0 0.0019 18.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EKG12600.1 - 7e-05 22.0 0.0 0.0036 16.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EKG12600.1 - 0.00076 18.9 1.1 0.037 13.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EKG12600.1 - 0.002 18.4 0.0 0.036 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EKG12600.1 - 0.0022 18.0 0.0 1 9.2 0.0 3.4 3 1 1 4 4 4 1 AAA domain AAA_17 PF13207.1 EKG12600.1 - 0.0024 18.6 0.0 0.084 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EKG12600.1 - 0.0038 16.4 0.0 0.031 13.5 0.0 2.4 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EKG12600.1 - 0.0076 16.3 0.3 0.76 9.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EKG12600.1 - 0.01 15.5 0.8 1.8 8.1 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EKG12600.1 - 0.078 12.7 0.5 9.2 6.1 0.2 2.6 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 EKG12600.1 - 0.13 12.7 0.0 22 5.5 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 EKG12600.1 - 0.15 12.2 0.0 31 4.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 EKG12600.1 - 0.25 11.2 0.0 35 4.3 0.0 2.7 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EKG12600.1 - 0.78 10.0 0.8 2.2 8.5 0.0 2.1 3 0 0 3 3 2 0 AAA domain Zn_clus PF00172.13 EKG12601.1 - 0.026 14.4 9.6 0.059 13.2 6.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 EKG12602.1 - 6.8e-17 60.7 0.3 7.9e-17 60.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain PhoD PF09423.5 EKG12603.1 - 3.4e-39 134.6 0.3 4e-39 134.4 0.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase DEAD PF00270.24 EKG12604.1 - 3.8e-45 153.4 0.9 1.1e-44 151.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG12604.1 - 2e-17 62.7 0.2 7.5e-17 60.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EKG12604.1 - 0.026 12.9 0.1 1 7.6 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1253) Cation_efflux PF01545.16 EKG12605.1 - 6.8e-30 104.1 2.1 8.4e-30 103.8 1.5 1.1 1 0 0 1 1 1 1 Cation efflux family EF-hand_1 PF00036.27 EKG12608.1 - 5.1e-26 87.9 12.8 8.8e-07 27.7 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKG12608.1 - 4.1e-23 81.2 3.4 1.3e-12 47.6 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKG12608.1 - 2.1e-20 70.7 5.1 4.2e-05 23.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKG12608.1 - 3.2e-18 64.1 12.9 2.4e-06 26.6 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EKG12608.1 - 3.9e-15 55.1 13.6 2e-05 24.1 0.7 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKG12608.1 - 6.1e-07 29.4 0.0 0.00054 19.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EKG12608.1 - 5.9e-06 25.9 7.6 0.0027 17.4 0.3 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EKG12608.1 - 0.043 13.7 0.1 1.9 8.4 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain CAF-1_p150 PF11600.3 EKG12610.1 - 0.43 9.9 24.4 0.6 9.4 16.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Drc1-Sld2 PF11719.3 EKG12610.1 - 2.3 7.2 14.8 3.2 6.7 10.3 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Hex_IIIa PF02455.11 EKG12610.1 - 6.3 5.3 9.1 8.6 4.9 6.3 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Ribosomal_S7 PF00177.16 EKG12611.1 - 6.8e-40 136.0 1.6 8.2e-40 135.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e CPSF73-100_C PF11718.3 EKG12612.1 - 2.4e-73 246.0 0.0 2e-72 243.0 0.0 2.0 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EKG12612.1 - 1.9e-32 111.8 0.0 5.7e-32 110.3 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EKG12612.1 - 8.3e-17 61.4 0.3 1.7e-16 60.4 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG12612.1 - 1e-11 44.7 0.3 2.1e-11 43.7 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EKG12612.1 - 3.4e-07 29.9 0.1 7.2e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EKG12612.1 - 1.1e-05 25.2 0.2 4.6e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EKG12613.1 - 2.8e-27 95.6 0.0 4.8e-21 75.2 0.0 2.5 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Borrelia_P83 PF05262.6 EKG12613.1 - 0.034 12.4 3.4 0.064 11.5 2.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_M24 PF00557.19 EKG12614.1 - 9.1e-60 201.7 0.0 1.6e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EKG12614.1 - 2.2e-20 72.3 0.0 5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Thaumatin PF00314.12 EKG12615.1 - 2.9e-73 245.8 5.6 3.5e-73 245.5 3.9 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_2_C PF02836.12 EKG12616.1 - 0.0013 17.6 0.0 0.0028 16.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.13 EKG12617.1 - 5.3e-27 94.3 0.1 1.2e-26 93.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Med15 PF09606.5 EKG12617.1 - 0.16 10.1 25.1 0.23 9.5 17.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EKG12617.1 - 0.64 8.1 20.0 0.95 7.6 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDP-OH_P_transf PF01066.16 EKG12618.1 - 1.4e-18 67.0 2.4 1.4e-18 67.0 1.7 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Beta-lactamase PF00144.19 EKG12620.1 - 1.4e-43 149.2 4.5 2.4e-43 148.4 3.1 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EKG12620.1 - 1.8e-06 27.6 0.1 0.0025 17.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3471) SNF2_N PF00176.18 EKG12621.1 - 4.1e-36 124.3 0.0 5.8e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EKG12621.1 - 0.058 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase UPF0061 PF02696.9 EKG12621.1 - 0.061 11.6 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family zf-C2H2_4 PF13894.1 EKG12622.1 - 6.4e-14 51.1 15.1 0.00068 19.7 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG12622.1 - 6.4e-13 48.2 19.3 1.9e-05 24.7 0.4 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG12622.1 - 1.1e-08 34.9 19.8 1.4e-05 25.1 0.4 5.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EKG12622.1 - 8.7e-07 28.9 6.8 0.022 14.8 1.6 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EKG12622.1 - 0.0013 18.3 4.5 0.44 10.2 0.1 3.0 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EKG12622.1 - 0.0065 16.3 7.3 0.15 11.9 1.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger RRN7 PF11781.3 EKG12622.1 - 0.0075 15.7 0.4 2 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EKG12622.1 - 0.026 14.3 1.4 0.067 13.0 1.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.7 EKG12622.1 - 0.14 12.2 9.2 0.093 12.8 1.2 3.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-DNA_Pol PF08996.5 EKG12622.1 - 0.19 11.0 6.3 0.039 13.3 0.6 2.4 3 0 0 3 3 3 0 DNA Polymerase alpha zinc finger CpXC PF14353.1 EKG12622.1 - 0.28 11.1 3.2 8.7 6.3 2.0 2.7 2 1 0 2 2 2 0 CpXC protein Terminase_GpA PF05876.7 EKG12622.1 - 0.37 9.0 1.8 0.53 8.5 1.2 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-C2H2_2 PF12756.2 EKG12622.1 - 0.42 10.7 6.5 0.29 11.2 1.4 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.13 EKG12622.1 - 1.4 9.3 12.0 0.11 12.9 2.4 2.7 2 1 0 2 2 2 0 TRAF-type zinc finger IBR PF01485.16 EKG12622.1 - 1.5 8.7 9.1 2.3e+02 1.7 6.3 3.3 1 1 0 1 1 1 0 IBR domain Elf1 PF05129.8 EKG12622.1 - 4.2 7.1 8.6 0.46 10.1 1.6 2.6 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like Transferase PF02458.10 EKG12623.1 - 0.045 12.1 0.0 0.052 11.9 0.0 1.1 1 0 0 1 1 1 0 Transferase family BTP PF05232.7 EKG12623.1 - 0.19 11.5 0.8 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family DUF2975 PF11188.3 EKG12624.1 - 0.002 17.8 1.1 0.002 17.8 0.8 3.4 3 1 1 4 4 4 2 Protein of unknown function (DUF2975) TruD PF01142.13 EKG12625.1 - 4e-58 196.9 4.3 2.9e-53 180.8 0.4 4.1 4 0 0 4 4 4 3 tRNA pseudouridine synthase D (TruD) KilA-N PF04383.8 EKG12625.1 - 0.01 15.4 0.9 6.4 6.4 0.0 2.8 2 1 0 2 2 2 0 KilA-N domain BRX_N PF13713.1 EKG12625.1 - 0.018 14.5 0.3 0.11 11.9 0.0 2.5 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain FA_hydroxylase PF04116.8 EKG12626.1 - 4.5e-18 65.7 9.9 4.5e-18 65.7 6.8 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 EKG12627.1 - 5.3e-65 218.4 2.2 5.9e-65 218.2 1.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Nse4-Nse3_bdg PF15412.1 EKG12627.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Ribosomal_S20p PF01649.13 EKG12627.1 - 0.019 15.3 0.9 0.031 14.6 0.7 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 UPF0223 PF05256.7 EKG12627.1 - 0.21 11.7 1.3 0.36 10.9 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) RdRP PF05183.7 EKG12628.1 - 5.1e-115 385.3 0.2 7e-115 384.9 0.1 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase N2227 PF07942.7 EKG12629.1 - 1.5e-89 299.6 0.0 1.8e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EKG12629.1 - 2.3e-07 30.6 0.0 5.6e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG12629.1 - 0.02 15.3 0.0 0.1 13.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EKG12629.1 - 0.075 12.6 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Pectate_lyase_3 PF12708.2 EKG12630.1 - 5e-88 295.0 23.5 2.2e-71 240.5 7.0 3.3 2 1 1 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EKG12630.1 - 2.9e-05 23.4 0.9 0.1 12.0 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EKG12630.1 - 0.63 9.7 21.6 0.033 13.9 6.8 3.7 3 1 0 3 3 3 0 Right handed beta helix region Aminotran_1_2 PF00155.16 EKG12631.1 - 7e-15 54.8 0.0 1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EKG12631.1 - 0.04 12.4 0.0 1.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Hexokinase_2 PF03727.11 EKG12632.1 - 0.01 15.0 0.1 0.022 13.9 0.1 1.5 1 0 0 1 1 1 0 Hexokinase Mtc PF03820.12 EKG12633.1 - 6.8e-97 323.8 0.3 4.6e-96 321.1 0.2 1.8 1 1 0 1 1 1 1 Tricarboxylate carrier Polysacc_synt_C PF14667.1 EKG12633.1 - 0.28 10.9 6.6 0.045 13.5 1.5 1.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain HSP70 PF00012.15 EKG12634.1 - 2.6e-61 207.2 16.3 4.9e-56 189.8 0.0 3.4 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 EKG12634.1 - 0.0058 15.2 0.0 0.013 14.0 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein Kelch_6 PF13964.1 EKG12635.1 - 0.0022 18.1 0.7 0.054 13.6 0.0 2.5 1 1 1 2 2 2 1 Kelch motif DUF605 PF04652.11 EKG12636.1 - 3.7 6.8 18.6 4.1 6.6 12.9 1.1 1 0 0 1 1 1 0 Vta1 like Tubulin_3 PF14881.1 EKG12639.1 - 8.9e-50 168.6 0.1 1.3e-49 168.1 0.1 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EKG12639.1 - 7.1e-39 132.4 0.0 1.3e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EKG12639.1 - 2.7e-05 24.0 0.0 0.0057 16.4 0.0 2.1 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Prp18 PF02840.10 EKG12640.1 - 1.2e-54 184.0 0.0 1.2e-54 184.0 0.0 2.2 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EKG12640.1 - 4.3e-11 41.8 1.3 4.3e-11 41.8 0.9 2.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Caldesmon PF02029.10 EKG12640.1 - 0.13 10.7 24.3 0.2 10.0 16.9 1.3 1 0 0 1 1 1 0 Caldesmon Ycf1 PF05758.7 EKG12640.1 - 0.4 8.3 5.3 0.41 8.2 3.7 1.1 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 EKG12640.1 - 8.9 5.8 16.1 16 5.0 11.2 1.5 1 0 0 1 1 1 0 IncA protein SAP18 PF06487.7 EKG12641.1 - 2.4e-37 127.4 0.0 3e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF1039 PF06287.6 EKG12641.1 - 0.063 13.1 0.3 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) ATG27 PF09451.5 EKG12642.1 - 1.3e-72 244.3 8.6 1.3e-70 237.7 6.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EKG12642.1 - 0.00031 20.5 0.0 0.012 15.3 0.0 2.7 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Cwf_Cwc_15 PF04889.7 EKG12642.1 - 0.0035 17.0 17.8 0.0049 16.6 12.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FLO_LFY PF01698.11 EKG12642.1 - 1.8 7.2 7.2 2.5 6.8 5.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Nop14 PF04147.7 EKG12642.1 - 1.9 6.3 18.1 2.2 6.1 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 EKG12642.1 - 4.7 7.5 18.8 0.63 10.3 7.3 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 EKG12642.1 - 5.5 5.6 23.1 7.8 5.0 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleo_P87 PF07267.6 EKG12642.1 - 8 5.0 8.9 11 4.5 6.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HET PF06985.6 EKG12644.1 - 1.2e-22 80.5 0.0 2.4e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) rve PF00665.21 EKG12651.1 - 2.7e-15 56.5 0.5 9.9e-15 54.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EKG12651.1 - 5.5e-11 42.2 0.1 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 EKG12651.1 - 1.1e-10 41.0 0.8 3.2e-10 39.5 0.5 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BRCT PF00533.21 EKG12652.1 - 1.3e-06 28.4 0.1 2.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKG12652.1 - 0.024 14.4 0.1 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain DUF3595 PF12166.3 EKG12652.1 - 0.087 11.6 0.7 0.19 10.5 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) NAD_binding_10 PF13460.1 EKG12658.1 - 2.1e-14 53.9 0.1 3.1e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG12658.1 - 1.7e-13 50.5 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG12658.1 - 2.7e-13 49.2 0.0 3.6e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EKG12658.1 - 6e-09 35.2 0.0 8.2e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EKG12658.1 - 1.9e-08 33.5 0.0 5.6e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EKG12658.1 - 6.5e-07 28.8 0.4 1e-06 28.1 0.3 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EKG12658.1 - 2.1e-05 24.4 0.1 7.5e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 EKG12658.1 - 0.019 14.6 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EKG12658.1 - 0.051 14.1 0.2 0.18 12.3 0.1 1.9 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RmlD_sub_bind PF04321.12 EKG12658.1 - 0.087 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Tautomerase_3 PF14832.1 EKG12659.1 - 1.6e-56 190.0 0.2 1.8e-56 189.8 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EKG12659.1 - 0.018 14.6 0.0 0.076 12.6 0.0 1.9 1 1 0 1 1 1 0 Tautomerase enzyme ADH_zinc_N PF00107.21 EKG12660.1 - 7e-10 38.5 0.8 2.9e-09 36.5 0.5 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG12660.1 - 3.2e-08 33.3 0.0 7.7e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 EKG12660.1 - 0.033 14.0 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus AlaDh_PNT_C PF01262.16 EKG12660.1 - 0.16 11.4 0.9 0.35 10.4 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EHN PF06441.7 EKG12662.1 - 6.8e-37 125.8 0.4 1.1e-36 125.1 0.3 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG12662.1 - 1e-12 48.4 0.2 2.7e-12 47.0 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG12662.1 - 2.1e-06 27.4 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold adh_short PF00106.20 EKG12663.1 - 6e-29 101.1 3.3 7.6e-29 100.7 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG12663.1 - 4.8e-15 55.9 0.1 6.2e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG12663.1 - 4.9e-10 39.3 2.3 1.2e-09 38.0 1.6 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG12663.1 - 8.4e-07 29.1 0.3 2.5e-06 27.6 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG12663.1 - 2.2e-06 27.2 0.4 6.4e-06 25.7 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EKG12663.1 - 0.00042 19.3 0.1 0.00062 18.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EKG12663.1 - 0.00052 19.0 0.0 0.0027 16.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 5-FTHF_cyc-lig PF01812.15 EKG12663.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family Eno-Rase_NADH_b PF12242.3 EKG12663.1 - 0.066 13.0 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EKG12663.1 - 0.075 11.9 0.1 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EKG12663.1 - 0.082 11.8 0.0 8 5.2 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein HNH_2 PF13391.1 EKG12664.1 - 5.6e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease Peptidase_C50 PF03568.12 EKG12664.1 - 0.038 12.6 5.4 0.055 12.1 3.7 1.1 1 0 0 1 1 1 0 Peptidase family C50 HAUS-augmin3 PF14932.1 EKG12664.1 - 0.064 12.4 8.1 0.12 11.5 5.6 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 zf-CCCH PF00642.19 EKG12665.1 - 0.00029 20.4 13.3 0.00029 20.4 2.5 3.4 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF904 PF06005.7 EKG12665.1 - 0.018 15.3 1.2 0.043 14.1 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) zf-CCCH_2 PF14608.1 EKG12665.1 - 0.033 14.1 7.0 0.23 11.4 1.1 3.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Peptidase_C12 PF01088.16 EKG12666.1 - 1.7e-71 239.8 0.0 2.4e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Arginase PF00491.16 EKG12669.1 - 6.8e-08 32.1 0.0 7.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EKG12669.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain PP-binding PF00550.20 EKG12670.1 - 0.001 19.3 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.15 EKG12670.1 - 0.017 14.0 0.1 0.03 13.1 0.0 1.5 2 0 0 2 2 2 0 Condensation domain Aldedh PF00171.17 EKG12674.1 - 6.4e-183 608.3 3.0 7.2e-183 608.1 2.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EKG12674.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Endonuc_subdom PF09062.5 EKG12674.1 - 0.18 12.5 0.0 0.33 11.7 0.0 1.3 1 0 0 1 1 1 0 PI-PfuI Endonuclease subdomain Abhydrolase_6 PF12697.2 EKG12676.1 - 3.6e-07 30.2 0.0 8.3e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG12676.1 - 0.00046 19.8 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EKG12676.1 - 0.002 17.2 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EKG12676.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EKG12676.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2324 PF10086.4 EKG12678.1 - 0.88 8.7 9.2 1.4 8.1 3.4 2.5 2 1 0 2 2 2 0 Putative membrane peptidase family (DUF2324) p450 PF00067.17 EKG12679.1 - 1.1e-51 175.8 0.0 3.3e-51 174.2 0.0 1.7 3 0 0 3 3 3 1 Cytochrome P450 p450 PF00067.17 EKG12680.1 - 4.1e-42 144.2 0.0 4.5e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG12681.1 - 4.4e-59 200.2 0.0 5.4e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2183 PF09949.4 EKG12683.1 - 2.1e-31 107.8 0.0 4.2e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Pyr_redox_3 PF13738.1 EKG12684.1 - 2.4e-13 50.6 0.0 6.1e-13 49.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG12684.1 - 1.7e-06 27.2 0.0 6.6e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pectinesterase PF01095.14 EKG12685.1 - 5.4e-53 179.4 5.6 6.6e-53 179.2 3.9 1.0 1 0 0 1 1 1 1 Pectinesterase SNF2_N PF00176.18 EKG12686.1 - 1.7e-60 204.4 0.0 2.6e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG12686.1 - 1.1e-13 50.8 0.0 2.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG12686.1 - 8e-06 25.4 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EKG12686.1 - 2.2e-05 23.4 0.3 7.5e-05 21.6 0.2 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 RWD PF05773.17 EKG12687.1 - 1.5e-08 34.5 0.0 2.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF1115 PF06544.7 EKG12687.1 - 9.6e-08 31.7 0.0 2.3e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Glyco_hydro_3_C PF01915.17 EKG12688.1 - 5.8e-69 232.0 0.0 2.6e-68 229.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EKG12688.1 - 1.6e-59 201.3 0.0 2.9e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EKG12688.1 - 7.1e-23 80.3 0.6 2.6e-22 78.5 0.2 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EKG12688.1 - 1e-16 60.8 0.1 2.3e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.1 EKG12688.1 - 0.043 13.9 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Phage_tail_X PF05489.7 EKG12688.1 - 0.061 12.8 0.1 0.19 11.2 0.1 1.8 1 0 0 1 1 1 0 Phage Tail Protein X PDGF_N PF04692.8 EKG12689.1 - 0.0053 17.2 0.2 0.0077 16.6 0.1 1.2 1 0 0 1 1 1 1 Platelet-derived growth factor, N terminal region Ank_2 PF12796.2 EKG12690.1 - 4.3e-24 84.6 0.0 1.9e-07 31.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG12690.1 - 1.4e-19 68.8 0.4 0.0054 16.4 0.1 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EKG12690.1 - 8.8e-19 65.7 0.1 0.0093 16.1 0.0 6.4 5 1 1 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EKG12690.1 - 8.6e-15 54.7 1.8 3e-05 24.3 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG12690.1 - 9.9e-14 51.0 6.4 0.00023 21.2 0.1 5.3 1 1 5 6 6 6 5 Ankyrin repeats (many copies) ADH_zinc_N PF00107.21 EKG12691.1 - 2.9e-12 46.2 0.2 8.3e-12 44.7 0.0 1.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG12691.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EKG12692.1 - 3.8e-40 137.6 39.4 3.8e-40 137.6 27.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily NKAIN PF05640.9 EKG12692.1 - 0.039 12.9 0.0 0.086 11.7 0.0 1.5 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein Fungal_trans PF04082.13 EKG12693.1 - 2.3e-06 26.7 0.0 3.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NifW PF03206.9 EKG12693.1 - 0.0054 16.8 0.1 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 Nitrogen fixation protein NifW SGL PF08450.7 EKG12694.1 - 1.3e-06 28.0 0.1 0.00095 18.6 0.1 2.5 2 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EKG12694.1 - 0.00075 19.3 0.1 0.43 10.6 0.0 3.7 3 0 0 3 3 3 1 NHL repeat Str_synth PF03088.11 EKG12694.1 - 0.082 12.9 0.0 6.5 6.8 0.0 2.5 1 1 1 2 2 2 0 Strictosidine synthase Lactonase PF10282.4 EKG12694.1 - 0.16 11.0 0.0 0.41 9.6 0.0 1.6 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Acyl_transf_1 PF00698.16 EKG12695.1 - 2.7e-93 312.8 0.2 4.3e-93 312.1 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EKG12695.1 - 7e-76 255.0 0.1 4e-75 252.5 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG12695.1 - 9.2e-58 194.8 0.0 3.4e-57 193.0 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EKG12695.1 - 4.8e-48 163.2 0.0 1.3e-47 161.8 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG12695.1 - 1.5e-37 128.0 2.7 1.5e-37 128.0 1.9 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EKG12695.1 - 1.1e-10 41.1 0.0 2.8e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EKG12695.1 - 1.3e-10 41.3 0.0 3.6e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EKG12695.1 - 1.5e-05 24.1 2.0 4.9e-05 22.4 0.3 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain DUF3022 PF11226.3 EKG12695.1 - 0.064 13.1 0.0 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) FMO-like PF00743.14 EKG12696.1 - 1.3e-29 102.8 0.0 8e-14 50.7 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EKG12696.1 - 5.4e-14 52.7 0.0 4.8e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG12696.1 - 5.7e-07 28.7 0.0 4e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EKG12696.1 - 1.5e-05 24.9 0.0 0.00081 19.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CAP PF00188.21 EKG12697.1 - 5.6e-14 52.6 4.3 8.2e-14 52.1 3.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family G_glu_transpept PF01019.16 EKG12698.1 - 4.3e-144 480.7 0.0 5.3e-144 480.4 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1757 PF08560.5 EKG12698.1 - 0.07 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) p450 PF00067.17 EKG12700.1 - 6.4e-56 189.7 0.0 8.7e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG12702.1 - 1.5e-08 34.7 0.4 2.2e-08 34.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Terpene_synth_C PF03936.11 EKG12703.1 - 1.4e-07 30.9 0.1 4.2e-07 29.4 0.1 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF3435 PF11917.3 EKG12704.1 - 2.1e-26 92.6 0.0 2.4e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Myb_DNA-bind_6 PF13921.1 EKG12705.1 - 9e-05 22.5 0.1 0.00016 21.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG12705.1 - 0.00034 20.6 0.2 0.00066 19.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF637 PF04830.8 EKG12705.1 - 0.042 13.4 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Possible hemagglutinin (DUF637) RNase_T PF00929.19 EKG12706.1 - 0.032 14.5 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Exonuclease RNase_H PF00075.19 EKG12708.1 - 0.0077 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EKG12708.1 - 0.026 14.8 0.7 0.11 12.7 0.1 2.1 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase DUF2075 PF09848.4 EKG12709.1 - 0.12 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) COesterase PF00135.23 EKG12710.1 - 1.9e-44 152.2 0.0 2.4e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG12710.1 - 8.4e-06 25.5 0.3 2.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG12710.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 EKG12711.1 - 8.1e-46 156.4 0.0 9.5e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG12712.1 - 6.9e-13 47.9 0.0 9e-13 47.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG12713.1 - 7.3e-53 179.7 0.0 9.6e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 EKG12714.1 - 4.9e-67 225.7 0.0 5.8e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HAP1_N PF04849.8 EKG12715.1 - 0.0023 16.9 3.7 0.0041 16.1 2.6 1.4 1 1 0 1 1 1 1 HAP1 N-terminal conserved region Baculo_PEP_C PF04513.7 EKG12715.1 - 0.0025 17.6 1.7 0.0039 17.0 1.2 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fmp27_WPPW PF10359.4 EKG12715.1 - 0.0097 14.3 0.3 0.014 13.8 0.2 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain CENP-Q PF13094.1 EKG12715.1 - 0.0097 15.9 3.1 0.019 14.9 2.1 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CASP_C PF08172.7 EKG12715.1 - 0.012 14.6 3.7 0.026 13.5 2.6 1.4 1 1 0 1 1 1 0 CASP C terminal CALCOCO1 PF07888.6 EKG12715.1 - 0.012 13.8 3.5 0.019 13.2 2.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.3 EKG12715.1 - 0.034 13.9 8.5 0.064 13.0 5.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EKG12715.1 - 0.039 13.8 4.1 0.08 12.8 2.9 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DivIVA PF05103.8 EKG12715.1 - 0.053 13.5 7.7 0.1 12.6 5.3 1.4 1 0 0 1 1 1 0 DivIVA protein IncA PF04156.9 EKG12715.1 - 0.08 12.5 1.2 0.12 11.9 0.9 1.3 1 0 0 1 1 1 0 IncA protein DUF2968 PF11180.3 EKG12715.1 - 0.085 12.2 6.9 0.21 10.9 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GBP_C PF02841.9 EKG12715.1 - 0.32 10.1 6.6 0.55 9.3 4.5 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CASP_C PF08172.7 EKG12716.1 - 3.5e-05 22.9 4.8 7.7e-05 21.8 3.1 1.6 1 1 1 2 2 2 1 CASP C terminal CENP-Q PF13094.1 EKG12716.1 - 0.00094 19.2 1.3 0.0015 18.5 0.9 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Fmp27_WPPW PF10359.4 EKG12716.1 - 0.0052 15.2 0.3 0.0066 14.9 0.2 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain HAP1_N PF04849.8 EKG12716.1 - 0.0075 15.2 2.6 0.012 14.5 1.8 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DivIVA PF05103.8 EKG12716.1 - 0.0089 16.0 7.0 0.016 15.2 4.9 1.3 1 0 0 1 1 1 1 DivIVA protein zf-CCHC_4 PF14392.1 EKG12716.1 - 0.016 14.8 8.2 0.2 11.3 1.1 2.5 2 0 0 2 2 2 0 Zinc knuckle TMF_DNA_bd PF12329.3 EKG12716.1 - 0.02 14.6 7.3 0.038 13.8 5.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF2968 PF11180.3 EKG12716.1 - 0.021 14.1 6.3 0.041 13.2 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TPD52 PF04201.10 EKG12716.1 - 0.023 14.4 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Tumour protein D52 family DUF932 PF06067.6 EKG12716.1 - 0.026 13.8 0.3 0.044 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) DUF3109 PF11307.3 EKG12716.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3109) ADIP PF11559.3 EKG12716.1 - 0.05 13.5 4.9 0.099 12.5 3.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PhoU PF01895.14 EKG12716.1 - 0.082 13.3 1.8 0.2 12.0 1.3 1.7 1 0 0 1 1 1 0 PhoU domain Mod_r PF07200.8 EKG12716.1 - 0.11 12.3 4.5 0.11 12.3 2.0 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3498 PF12004.3 EKG12716.1 - 0.12 11.4 7.4 0.064 12.3 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3498) IncA PF04156.9 EKG12716.1 - 0.16 11.5 2.2 0.25 10.9 1.5 1.2 1 0 0 1 1 1 0 IncA protein DUF16 PF01519.11 EKG12716.1 - 0.18 12.0 2.1 0.32 11.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 GBP_C PF02841.9 EKG12716.1 - 0.25 10.4 6.5 0.37 9.9 4.5 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TMCO5 PF14992.1 EKG12716.1 - 0.29 10.2 6.4 0.43 9.6 4.5 1.2 1 0 0 1 1 1 0 TMCO5 family APG6 PF04111.7 EKG12716.1 - 0.88 8.5 4.6 1.3 7.9 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-CCHC PF00098.18 EKG12716.1 - 3.7 7.6 18.1 0.66 10.0 1.9 3.4 3 0 0 3 3 3 0 Zinc knuckle DUF948 PF06103.6 EKG12716.1 - 4.8 7.1 6.0 14 5.6 0.5 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-CCHC_3 PF13917.1 EKG12716.1 - 9.7 6.0 10.9 9.8 6.0 3.9 2.7 1 1 1 2 2 2 0 Zinc knuckle DUF3435 PF11917.3 EKG12717.1 - 8.4e-30 103.8 0.0 1.2e-29 103.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Pkinase PF00069.20 EKG12718.1 - 5e-20 71.7 0.0 6.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12718.1 - 4.3e-11 42.3 0.0 6.1e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG12718.1 - 0.00021 21.1 0.8 0.0059 16.3 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EKG12718.1 - 0.027 13.5 0.1 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKG12718.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EKG12718.1 - 0.11 11.8 0.1 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DAP10 PF07213.6 EKG12721.1 - 0.15 11.8 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Dimer_Tnp_hAT PF05699.9 EKG12725.1 - 4.6e-15 55.0 0.0 1.1e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ank_2 PF12796.2 EKG12728.1 - 1.2e-91 301.1 0.0 5.2e-16 58.7 0.0 6.7 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG12728.1 - 5.4e-72 237.0 0.6 2.5e-11 43.7 0.0 8.3 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG12728.1 - 1.9e-71 234.4 3.6 2.2e-12 46.7 0.0 7.6 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.25 EKG12728.1 - 1.5e-54 179.2 0.0 1.6e-07 30.7 0.0 9.8 10 1 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.1 EKG12728.1 - 4.7e-46 150.1 0.0 1.1e-05 25.1 0.0 10.6 11 0 0 11 11 11 8 Ankyrin repeat TolA PF06519.6 EKG12728.1 - 0.00049 20.0 0.1 7.3 6.6 0.0 4.7 2 1 3 5 5 5 1 TolA C-terminal DLH PF01738.13 EKG12728.1 - 0.15 11.3 0.0 5.6 6.1 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family Glyco_hydro_43 PF04616.9 EKG12732.1 - 0.0021 17.1 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 JmjC PF02373.17 EKG12733.1 - 1.6e-22 79.8 0.0 4.5e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase EST1_DNA_bind PF10373.4 EKG12734.1 - 2.4e-09 36.8 0.5 5.9e-09 35.5 0.4 1.7 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain zf-Di19 PF05605.7 EKG12734.1 - 0.0048 17.0 0.4 0.012 15.7 0.3 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.1 EKG12734.1 - 0.067 12.9 2.4 0.16 11.7 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Toxin_42 PF15522.1 EKG12734.1 - 0.068 12.3 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 42 Cytochrom_B_N PF00033.14 EKG12737.1 - 0.0052 16.1 4.3 0.011 15.1 3.0 1.6 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB DUF1469 PF07332.6 EKG12737.1 - 1.4 8.6 9.4 0.89 9.2 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Trs65 PF12735.2 EKG12740.1 - 0.76 9.0 4.1 0.35 10.1 0.1 1.9 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 MULE PF10551.4 EKG12741.1 - 1.7e-16 60.1 0.0 4.7e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 EKG12741.1 - 0.00022 19.9 0.2 0.00033 19.3 0.1 1.2 1 0 0 1 1 1 1 Transposase, Mutator family XdhC_C PF13478.1 EKG12743.1 - 0.056 13.7 0.2 0.077 13.3 0.1 1.1 1 0 0 1 1 1 0 XdhC Rossmann domain MerC PF03203.9 EKG12744.1 - 1.3 9.4 4.6 2.7 8.4 3.1 1.6 1 1 0 1 1 1 0 MerC mercury resistance protein Abhydrolase_3 PF07859.8 EKG12745.1 - 1.8e-63 213.8 0.1 2.3e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG12745.1 - 1.1e-07 30.9 0.0 2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EKG12745.1 - 5.8e-05 22.8 0.1 8.1e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG12745.1 - 6.6e-05 22.2 0.1 0.00017 20.8 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EKG12745.1 - 0.047 12.3 0.0 0.32 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) DLH PF01738.13 EKG12745.1 - 0.049 12.9 0.0 0.21 10.8 0.0 2.0 3 0 0 3 3 3 0 Dienelactone hydrolase family Ribonuc_L-PSP PF01042.16 EKG12746.1 - 1.8e-38 130.9 0.0 2e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NB-ARC PF00931.17 EKG12747.1 - 2.3e-12 46.3 0.2 3.3e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EKG12747.1 - 4e-06 27.0 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG12747.1 - 1.6e-05 25.0 0.3 0.00016 21.7 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EKG12747.1 - 0.0013 18.4 0.1 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 EKG12747.1 - 0.075 12.4 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 EKG12748.1 - 2.4e-12 46.8 0.0 0.00058 19.6 0.0 4.1 1 1 3 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus SseC PF04888.7 EKG12748.1 - 0.051 12.8 6.1 7.3 5.8 4.0 2.9 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family MgtE_N PF03448.12 EKG12749.1 - 0.02 15.2 0.5 33 4.8 0.0 4.5 5 0 0 5 5 5 0 MgtE intracellular N domain Utp12 PF04003.7 EKG12749.1 - 0.026 14.4 0.9 1.2 9.0 0.0 3.3 3 0 0 3 3 3 0 Dip2/Utp12 Family Drf_DAD PF06345.6 EKG12749.1 - 1.3 8.9 5.5 4.9 7.1 0.7 2.8 2 0 0 2 2 2 0 DRF Autoregulatory Domain HET PF06985.6 EKG12751.1 - 6.8e-23 81.3 0.7 3.2e-18 66.2 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NB-ARC PF00931.17 EKG12751.1 - 7.3e-08 31.6 0.2 2.5e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EKG12751.1 - 1.8e-05 24.8 0.4 0.0002 21.3 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG12751.1 - 1.8e-05 24.8 0.0 4.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EKG12751.1 - 0.00056 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EKG12751.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase adh_short PF00106.20 EKG12752.1 - 8.4e-22 77.8 2.8 1.2e-21 77.3 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG12752.1 - 6e-09 35.8 2.4 8.8e-09 35.2 1.6 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG12752.1 - 6.5e-06 25.7 0.1 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EKG12752.1 - 0.0029 17.9 0.5 0.34 11.2 0.0 2.8 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.10 EKG12752.1 - 0.02 14.5 0.2 0.035 13.7 0.0 1.5 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ABC2_membrane PF01061.19 EKG12753.1 - 5.9e-36 123.5 18.1 5.9e-36 123.5 12.5 2.0 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EKG12753.1 - 6.6e-05 22.5 2.0 0.00019 21.0 1.4 1.8 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EKG12753.1 - 1.1 8.2 10.3 2.2 7.2 7.2 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 EKG12754.1 - 9.2e-44 149.1 15.6 9.2e-44 149.1 10.8 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EKG12754.1 - 4.3e-38 130.7 0.0 3.5e-19 69.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG12754.1 - 2.3e-30 104.2 1.0 9.8e-30 102.2 0.0 2.2 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.1 EKG12754.1 - 1.4e-13 50.7 0.0 3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EKG12754.1 - 5e-10 39.0 1.2 4.4e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EKG12754.1 - 3.5e-09 36.1 6.8 5.8e-09 35.4 4.7 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF258 PF03193.11 EKG12754.1 - 1.4e-05 24.3 0.3 0.00062 18.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG12754.1 - 0.00011 22.2 4.9 0.0025 17.8 0.1 3.2 3 1 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.1 EKG12754.1 - 0.00014 21.2 2.9 0.0052 16.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EKG12754.1 - 0.00061 19.2 1.1 0.031 13.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EKG12754.1 - 0.00073 19.8 0.0 0.34 11.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EKG12754.1 - 0.0043 16.9 0.2 0.33 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKG12754.1 - 0.0047 16.8 0.1 1.4 8.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKG12754.1 - 0.0048 17.0 0.4 0.56 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EKG12754.1 - 0.0052 16.7 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG12754.1 - 0.0094 16.7 0.1 0.17 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EKG12754.1 - 0.018 14.5 0.1 7.4 5.9 0.1 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family Miro PF08477.8 EKG12754.1 - 0.026 15.0 0.2 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein ABC2_membrane_2 PF12679.2 EKG12754.1 - 0.028 13.2 12.3 0.065 12.0 8.3 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein NACHT PF05729.7 EKG12754.1 - 0.047 13.3 3.2 0.72 9.4 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EKG12754.1 - 0.054 13.4 0.3 0.054 13.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EKG12754.1 - 0.16 11.1 0.0 12 4.9 0.0 2.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EKG12754.1 - 0.2 11.0 1.1 13 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EKG12754.1 - 0.26 11.6 0.0 0.52 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EKG12754.1 - 0.29 10.6 1.7 1.5 8.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation LcnG-beta PF11632.3 EKG12754.1 - 0.38 10.5 1.7 1.7 8.4 0.7 2.5 2 0 0 2 2 2 0 Lactococcin G-beta AAA_19 PF13245.1 EKG12754.1 - 0.5 10.1 6.2 1.7 8.4 0.5 2.9 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 EKG12754.1 - 0.72 9.4 3.3 0.3 10.7 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Neuralized PF07177.7 EKG12755.1 - 0.046 13.5 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Neuralized TnpV PF14198.1 EKG12755.1 - 0.12 12.3 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Acyltransferase PF01553.16 EKG12756.1 - 4.8e-25 87.5 0.0 7.8e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ADH_zinc_N PF00107.21 EKG12758.1 - 1.9e-13 50.0 0.1 3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG12758.1 - 5.4e-05 22.9 0.0 0.00023 20.8 0.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EKG12758.1 - 0.041 13.4 0.3 0.07 12.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 EKG12758.1 - 0.055 14.3 0.0 0.12 13.2 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase WD40 PF00400.27 EKG12759.1 - 6.4e-41 136.8 7.2 2.2e-13 49.5 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.7 EKG12759.1 - 1.3e-29 103.0 0.1 1.6e-28 99.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain HET PF06985.6 EKG12759.1 - 2.5e-21 76.2 5.8 1.1e-18 67.6 0.1 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nup160 PF11715.3 EKG12759.1 - 5.2e-09 34.7 2.3 0.02 13.0 0.0 3.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 AAA_22 PF13401.1 EKG12759.1 - 0.0047 17.0 0.2 0.15 12.2 0.0 2.8 2 1 1 3 3 3 1 AAA domain BBS2_Mid PF14783.1 EKG12759.1 - 0.011 15.5 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region AAA_16 PF13191.1 EKG12759.1 - 0.022 14.7 0.1 0.17 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Nbas_N PF15492.1 EKG12759.1 - 0.03 13.4 2.6 11 5.0 0.0 3.2 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.1 EKG12759.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EKG12759.1 - 0.077 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 EKG12759.1 - 0.18 10.7 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PEMT PF04191.8 EKG12760.1 - 2.9e-53 178.4 9.2 1.8e-31 108.3 0.9 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase Epimerase PF01370.16 EKG12762.1 - 6.9e-16 58.3 0.0 8.8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG12762.1 - 4.5e-13 48.6 0.0 1.6e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EKG12762.1 - 1e-09 37.4 0.0 1.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG12762.1 - 3.8e-07 30.3 0.1 8e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EKG12762.1 - 7.5e-07 29.2 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG12762.1 - 0.00068 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EKG12762.1 - 0.0027 16.9 0.1 0.0076 15.5 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EKG12762.1 - 0.0079 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.15 EKG12762.1 - 0.0088 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Med7 PF05983.6 EKG12764.1 - 3.9e-09 36.5 2.2 5e-09 36.1 1.5 1.2 1 0 0 1 1 1 1 MED7 protein TPT PF03151.11 EKG12765.1 - 2.4e-19 69.4 19.1 6.6e-17 61.5 2.1 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EKG12765.1 - 2e-09 37.5 20.7 4.2e-07 30.0 2.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EKG12765.1 - 1e-06 27.9 10.9 1.6e-06 27.3 7.6 1.3 1 1 0 1 1 1 1 UAA transporter family Tom5 PF10642.4 EKG12765.1 - 0.0071 15.9 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial import receptor subunit or translocase MFS_1 PF07690.11 EKG12766.1 - 1.7e-45 155.2 47.2 3.5e-45 154.2 32.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12766.1 - 9e-12 44.2 14.1 9e-12 44.2 9.8 3.1 3 2 1 4 4 4 2 Sugar (and other) transporter DUF2140 PF09911.4 EKG12766.1 - 0.035 13.2 0.4 0.059 12.5 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Gly-zipper_OmpA PF13436.1 EKG12767.1 - 1.7 8.3 12.5 2.9 7.5 8.7 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain HSP70 PF00012.15 EKG12768.1 - 6.8e-268 889.5 13.0 7.7e-268 889.3 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKG12768.1 - 6.9e-20 70.8 0.3 8.7e-19 67.2 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EKG12768.1 - 0.007 15.2 0.4 0.14 10.9 0.1 2.4 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EKG12768.1 - 0.031 13.8 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EKG12768.1 - 0.071 12.1 3.5 0.54 9.2 0.1 3.0 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 EKG12768.1 - 3.6 7.4 10.0 2.8 7.7 0.2 4.0 4 1 0 4 4 4 0 Cell division protein FtsA DUF3329 PF11808.3 EKG12769.1 - 0.97 9.5 3.2 3 7.9 2.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) SET PF00856.23 EKG12770.1 - 0.0026 18.0 0.0 0.006 16.8 0.0 1.6 1 1 0 1 1 1 1 SET domain Zn_clus PF00172.13 EKG12771.1 - 0.0066 16.3 9.2 0.015 15.1 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EKG12771.1 - 0.053 13.3 0.0 0.053 13.3 0.0 2.7 2 1 0 2 2 2 0 PAS fold IncA PF04156.9 EKG12771.1 - 0.054 13.0 7.2 0.092 12.3 5.0 1.4 1 0 0 1 1 1 0 IncA protein ISN1 PF06437.6 EKG12771.1 - 0.29 9.7 3.9 0.44 9.1 2.7 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Med15 PF09606.5 EKG12771.1 - 1.8 6.6 62.6 0.15 10.2 26.1 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MFS_1 PF07690.11 EKG12772.1 - 2.2e-25 89.1 39.5 1.1e-13 50.6 8.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Fzo_mitofusin PF04799.8 EKG12773.1 - 0.39 10.0 3.1 0.57 9.5 2.2 1.2 1 0 0 1 1 1 0 fzo-like conserved region V_ATPase_I PF01496.14 EKG12773.1 - 3 5.5 8.5 3.8 5.2 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hamartin PF04388.7 EKG12773.1 - 5.9 5.4 8.1 7.9 5.0 5.6 1.1 1 0 0 1 1 1 0 Hamartin protein HAUS6_N PF14661.1 EKG12773.1 - 8.6 5.6 12.0 17 4.6 8.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus TFIIS_M PF07500.9 EKG12774.1 - 2.7e-17 62.8 0.1 6.2e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EKG12774.1 - 3.1e-12 47.0 0.0 6.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EKG12774.1 - 3.2e-11 42.7 11.8 5.6e-11 41.9 8.2 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EKG12774.1 - 0.02 14.1 5.1 0.034 13.4 3.5 1.3 1 0 0 1 1 1 0 PHD-finger DUF2296 PF10058.4 EKG12774.1 - 1.9 8.2 6.3 4.3 7.1 4.3 1.6 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) MARVEL PF01284.18 EKG12776.1 - 0.00096 18.9 3.6 0.0013 18.5 2.5 1.4 1 0 0 1 1 1 1 Membrane-associating domain DUF4191 PF13829.1 EKG12776.1 - 0.78 8.8 2.9 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) NAD_binding_1 PF00175.16 EKG12777.1 - 0.0097 16.4 0.0 0.017 15.6 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain 2-Hacid_dh_C PF02826.14 EKG12778.1 - 1.7e-57 193.4 0.0 3e-57 192.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG12778.1 - 3e-36 123.8 0.4 5.3e-36 123.0 0.3 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EKG12778.1 - 0.0015 18.8 0.0 0.0099 16.1 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 EKG12778.1 - 0.012 15.4 0.4 0.026 14.3 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AlaDh_PNT_C PF01262.16 EKG12778.1 - 0.018 14.6 0.4 0.049 13.1 0.2 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EKG12778.1 - 0.038 13.6 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EKG12778.1 - 0.072 13.3 0.1 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Glyoxalase PF00903.20 EKG12779.1 - 8.1e-40 135.7 0.2 2.5e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EKG12779.1 - 4.2e-34 117.4 0.1 9e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EKG12779.1 - 3.9e-18 65.4 0.1 3.9e-07 30.0 0.0 4.3 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EKG12779.1 - 4.3e-08 33.2 0.0 0.0046 16.8 0.0 3.3 1 1 2 3 3 3 3 Glyoxalase-like domain PRT_C PF08372.5 EKG12779.1 - 0.011 15.2 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal CppA_N PF14506.1 EKG12779.1 - 0.03 14.0 0.3 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 CppA N-terminal MoaF PF10703.4 EKG12779.1 - 0.053 12.5 0.0 0.47 9.4 0.0 2.0 2 0 0 2 2 2 0 Molybdenum cofactor biosynthesis protein F SNF2_N PF00176.18 EKG12782.1 - 5.4e-69 232.2 0.0 1.1e-68 231.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG12782.1 - 9.1e-11 41.4 0.0 2.2e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG12782.1 - 6.3e-06 25.7 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Epimerase PF01370.16 EKG12783.1 - 9.6e-11 41.5 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG12783.1 - 2.1e-07 29.9 0.0 3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG12783.1 - 1.3e-05 24.2 0.4 0.00097 18.1 0.0 2.4 3 0 0 3 3 3 2 Male sterility protein adh_short PF00106.20 EKG12783.1 - 0.00057 19.8 1.2 0.0036 17.2 0.4 2.5 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EKG12783.1 - 0.00097 19.1 0.2 0.0034 17.4 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG12783.1 - 0.0018 17.5 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Abhydrolase_3 PF07859.8 EKG12784.1 - 5.7e-25 88.1 0.0 7.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EKG12784.1 - 6.2e-08 31.6 0.0 8.7e-08 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EKG12784.1 - 0.044 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EKG12784.1 - 0.065 11.9 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_S9 PF00326.16 EKG12784.1 - 0.1 11.8 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_C2 PF00648.16 EKG12785.1 - 4.4e-62 209.7 2.6 1.4e-39 135.8 0.3 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease GRP PF07172.6 EKG12785.1 - 0.0036 17.7 13.8 0.0036 17.7 9.5 6.3 6 1 1 7 7 7 2 Glycine rich protein family TMEM51 PF15345.1 EKG12785.1 - 0.92 9.1 7.2 0.49 10.0 2.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 PTPA PF03095.10 EKG12787.1 - 3e-90 302.4 0.0 3.5e-90 302.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF1772 PF08592.6 EKG12788.1 - 0.89 9.2 3.1 0.47 10.1 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) FtsJ PF01728.14 EKG12790.1 - 2.1e-61 207.0 0.0 2.6e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 EKG12791.1 - 2.5e-40 137.7 0.0 5.3e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG12791.1 - 3.6e-23 81.2 0.0 1.2e-22 79.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EKG12791.1 - 1.4e-05 23.7 0.0 0.0023 16.4 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1253) SNF2_N PF00176.18 EKG12791.1 - 0.0078 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EKG12791.1 - 0.017 15.2 0.7 0.34 11.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 EKG12791.1 - 0.03 14.1 0.0 0.03 14.1 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF3354 PF11834.3 EKG12791.1 - 0.11 12.1 2.6 0.29 10.7 1.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) eIF3_p135 PF12807.2 EKG12791.1 - 3.1 7.7 5.6 0.55 10.1 0.0 2.5 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit 135 tRNA-synt_2 PF00152.15 EKG12793.1 - 3.6e-89 298.8 5.4 4.2e-89 298.6 3.8 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EKG12793.1 - 1.2e-06 27.9 0.4 0.0024 17.1 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EKG12793.1 - 0.00037 20.3 0.0 0.0014 18.4 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EKG12793.1 - 0.048 13.2 3.2 0.92 9.0 0.1 2.6 3 0 0 3 3 3 0 tRNA synthetase class II core domain (G, H, P, S and T) Homez PF11569.3 EKG12793.1 - 0.078 12.0 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez EHN PF06441.7 EKG12794.1 - 4.2e-28 97.5 0.1 6.9e-28 96.8 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG12794.1 - 1e-10 41.8 0.5 4.8e-10 39.6 0.4 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG12794.1 - 1.7e-09 37.5 0.1 1.5e-08 34.4 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold DIOX_N PF14226.1 EKG12795.1 - 5.8e-23 81.6 0.1 9.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG12795.1 - 6.6e-13 48.8 0.0 1.4e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF447 PF04289.7 EKG12795.1 - 0.086 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) 2OG-FeII_Oxy_2 PF13532.1 EKG12796.1 - 8.6e-34 117.0 0.0 1.1e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EKG12796.1 - 0.042 14.3 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EKG12797.1 - 3.4e-74 249.2 0.0 3.9e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12797.1 - 2.9e-32 111.7 0.0 3.7e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG12797.1 - 0.00037 19.5 0.0 0.0016 17.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKG12797.1 - 0.0098 15.6 0.0 0.035 13.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EKG12797.1 - 0.068 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Dynamin_N PF00350.18 EKG12798.1 - 7e-24 84.5 0.0 2.1e-22 79.7 0.0 2.6 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EKG12798.1 - 1.9e-22 79.3 0.0 1.8e-21 76.2 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EKG12798.1 - 3.2e-07 30.1 0.4 1.1e-06 28.4 0.3 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EKG12798.1 - 1.6e-05 24.8 0.9 0.00075 19.4 0.1 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EKG12798.1 - 0.0011 19.3 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EKG12798.1 - 0.0013 19.0 0.0 0.0054 17.0 0.0 2.0 1 0 0 1 1 1 1 ABC transporter IIGP PF05049.8 EKG12798.1 - 0.013 14.2 1.4 0.18 10.6 0.4 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MADF_DNA_bdg PF10545.4 EKG12798.1 - 0.021 15.0 0.1 0.079 13.1 0.1 2.0 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_16 PF13191.1 EKG12798.1 - 0.12 12.3 3.7 1.3 8.9 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 EKG12798.1 - 0.13 11.8 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTP_transferase PF00483.18 EKG12799.1 - 1.8e-29 102.8 0.0 2.2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EKG12799.1 - 2.2e-09 36.4 11.2 1.9e-07 30.2 0.2 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EKG12799.1 - 8.5e-08 32.4 0.0 1.4e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EKG12799.1 - 0.014 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.1 EKG12799.1 - 0.46 10.0 4.8 0.47 10.0 0.0 3.0 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Amidase PF01425.16 EKG12800.1 - 8.6e-78 262.1 0.1 1.2e-77 261.6 0.1 1.1 1 0 0 1 1 1 1 Amidase PAT1 PF09770.4 EKG12801.1 - 0.012 13.9 86.9 0.15 10.3 37.7 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 ABC_tran PF00005.22 EKG12802.1 - 5.8e-24 84.9 0.5 4.6e-20 72.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EKG12802.1 - 1.9e-12 47.7 0.1 0.0027 17.7 0.0 3.3 3 0 0 3 3 3 3 AAA domain SMC_N PF02463.14 EKG12802.1 - 2.1e-07 30.4 0.1 0.063 12.4 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 EKG12802.1 - 0.0026 17.6 0.6 0.0045 16.8 0.0 1.6 2 0 0 2 2 2 1 Dynamin family ABC_tran_2 PF12848.2 EKG12802.1 - 0.003 17.3 6.5 0.0061 16.3 4.5 1.5 1 0 0 1 1 1 1 ABC transporter SbcCD_C PF13558.1 EKG12802.1 - 0.0034 17.2 0.0 0.079 12.8 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EKG12802.1 - 0.0053 16.6 0.1 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG12802.1 - 0.0062 16.5 0.1 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EKG12802.1 - 0.066 13.5 1.2 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EKG12802.1 - 0.089 12.2 0.1 0.35 10.2 0.1 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EKG12802.1 - 0.15 11.5 1.3 0.19 11.3 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF3584 PF12128.3 EKG12802.1 - 3 5.0 6.6 1.2 6.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Fe-ADH PF00465.14 EKG12804.1 - 3.7e-105 351.5 0.0 4.7e-105 351.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKG12804.1 - 2.9e-16 59.5 0.0 9.4e-13 48.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EKG12804.1 - 0.00071 19.0 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DNA_photolyase PF00875.13 EKG12804.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 DNA photolyase NmrA PF05368.8 EKG12805.1 - 3.1e-22 78.9 0.0 4.3e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG12805.1 - 6.1e-11 42.6 0.0 1.5e-08 34.8 0.0 2.4 1 1 1 2 2 2 2 NADH(P)-binding MAT1 PF06391.8 EKG12806.1 - 3e-39 134.6 14.0 4.1e-39 134.2 9.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EKG12806.1 - 0.0027 17.3 6.9 0.006 16.2 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG12806.1 - 0.015 14.9 5.4 0.028 14.0 3.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF572 PF04502.8 EKG12806.1 - 0.057 12.6 6.3 0.08 12.1 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-RING_2 PF13639.1 EKG12806.1 - 0.13 12.0 4.6 0.28 11.0 3.2 1.6 1 0 0 1 1 1 0 Ring finger domain AAA_16 PF13191.1 EKG12806.1 - 0.15 12.0 3.8 0.072 13.0 0.4 2.1 2 0 0 2 2 2 0 AAA ATPase domain zf-C3HC4_2 PF13923.1 EKG12806.1 - 0.32 11.0 5.9 0.71 9.9 4.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG12806.1 - 0.56 9.9 8.8 2.6 7.8 6.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain APG6 PF04111.7 EKG12806.1 - 1.5 7.8 8.5 2.4 7.1 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_3 PF13758.1 EKG12807.1 - 7.4e-20 70.5 1.7 7.4e-20 70.5 1.2 1.9 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EKG12807.1 - 2.4e-15 57.2 0.0 2.4e-15 57.2 0.0 5.5 5 2 1 6 6 6 2 Domain of unknown function (DUF3835) DUF21 PF01595.15 EKG12808.1 - 1.9e-34 118.5 0.2 2.9e-34 117.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EKG12808.1 - 1.7e-06 27.7 0.1 0.04 13.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain Transket_pyr PF02779.19 EKG12809.1 - 1.3e-35 122.5 0.0 2.1e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EKG12809.1 - 7.9e-33 113.0 0.0 1.9e-32 111.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain PhzC-PhzF PF02567.11 EKG12810.1 - 1.2e-34 119.8 0.1 2.8e-24 85.8 0.0 2.0 2 0 0 2 2 2 2 Phenazine biosynthesis-like protein PT-VENN PF04829.8 EKG12810.1 - 1.1 8.8 4.3 5.9 6.5 0.1 2.3 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Ferric_reduct PF01794.14 EKG12811.1 - 4.3e-08 33.2 14.2 2.4e-06 27.6 2.1 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EKG12811.1 - 1.5e-07 31.2 0.0 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.7 EKG12811.1 - 0.025 14.4 0.0 0.063 13.1 0.0 1.6 2 0 0 2 2 2 0 Ferric reductase NAD binding domain BUD22 PF09073.5 EKG12812.1 - 3.1e-81 273.6 40.3 4.3e-81 273.1 27.9 1.2 1 0 0 1 1 1 1 BUD22 Sugar_tr PF00083.19 EKG12813.1 - 4.1e-73 246.4 21.5 4.7e-73 246.3 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG12813.1 - 2.6e-23 82.3 26.9 2.1e-22 79.3 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EKG12814.1 - 5.1e-33 114.2 32.5 5.1e-33 114.2 22.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily A_deaminase PF00962.17 EKG12815.1 - 2.6e-21 75.8 0.0 3.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EKG12815.1 - 0.054 13.5 0.1 0.22 11.4 0.1 1.7 1 1 1 2 2 2 0 Amidohydrolase ATG13 PF10033.4 EKG12816.1 - 7e-59 199.0 0.0 1.2e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Zn_clus PF00172.13 EKG12817.1 - 5.2e-09 35.8 12.3 8.5e-09 35.1 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 EKG12819.1 - 1.2e-20 72.4 0.7 1.2e-20 72.4 0.5 2.5 1 1 1 2 2 2 1 Copper fist DNA binding domain DUF747 PF05346.6 EKG12821.1 - 3.4e-132 440.5 1.5 4.2e-132 440.2 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family zf-RING_2 PF13639.1 EKG12822.1 - 9.4e-10 38.1 1.1 1.4e-09 37.6 0.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKG12822.1 - 1.5e-09 37.8 0.5 3.3e-09 36.7 0.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EKG12822.1 - 0.00011 22.0 0.4 0.001 18.8 0.3 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EKG12822.1 - 0.013 15.1 0.6 0.024 14.3 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG12822.1 - 0.025 14.6 1.2 0.045 13.7 0.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG12822.1 - 0.2 11.3 0.8 0.88 9.2 0.5 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) YcbB PF08664.5 EKG12824.1 - 0.066 13.0 1.0 0.21 11.3 0.3 2.0 2 0 0 2 2 2 0 YcbB domain PEP-utilisers_N PF05524.8 EKG12824.1 - 0.13 12.0 4.3 0.13 12.0 0.5 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Aminotran_5 PF00266.14 EKG12825.1 - 3.1e-16 59.1 0.0 1.9e-14 53.2 0.0 3.2 1 1 0 1 1 1 1 Aminotransferase class-V ABC2_membrane PF01061.19 EKG12826.1 - 2.4e-30 105.3 23.1 3.4e-30 104.8 16.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EKG12826.1 - 4.9e-25 88.4 0.1 8e-25 87.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKG12826.1 - 2.6e-09 37.4 0.9 5.3e-05 23.3 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EKG12826.1 - 3.6e-05 23.8 0.3 7.8e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EKG12826.1 - 0.00015 21.1 0.0 0.0012 18.2 0.1 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKG12826.1 - 0.00046 19.4 0.1 0.00076 18.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKG12826.1 - 0.0015 18.6 0.0 0.0056 16.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG12826.1 - 0.0022 17.6 0.2 0.0049 16.5 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EKG12826.1 - 0.0048 17.7 0.0 0.012 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EKG12826.1 - 0.005 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKG12826.1 - 0.0056 16.1 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EKG12826.1 - 0.0092 15.4 0.5 0.025 14.0 0.3 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EKG12826.1 - 0.0094 15.0 0.1 0.12 11.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EKG12826.1 - 0.013 14.9 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 EKG12826.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EKG12826.1 - 0.017 14.7 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EKG12826.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EKG12826.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EKG12826.1 - 0.037 13.2 0.1 0.38 9.9 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EKG12826.1 - 0.041 13.8 0.0 0.17 11.8 0.0 2.1 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EKG12826.1 - 0.046 13.9 0.2 0.32 11.1 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EKG12826.1 - 0.053 12.1 0.0 0.077 11.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein T2SE PF00437.15 EKG12826.1 - 0.056 12.3 0.1 0.094 11.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EKG12826.1 - 0.091 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EKG12826.1 - 0.11 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EKG12826.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.4 EKG12826.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EKG12826.1 - 0.19 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_13 PF13166.1 EKG12826.1 - 0.2 10.0 0.4 2.2 6.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF4407 PF14362.1 EKG12827.1 - 0.15 11.0 3.5 0.23 10.3 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 EKG12827.1 - 1.1 8.0 6.2 2 7.2 4.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EKG12827.1 - 4.8 6.7 8.4 8 6.0 5.8 1.3 1 0 0 1 1 1 0 IncA protein F-actin_cap_A PF01267.12 EKG12829.1 - 4.9e-72 242.2 0.0 5.4e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit VHS PF00790.14 EKG12832.1 - 4.5e-25 87.9 0.0 9.3e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EKG12832.1 - 1.5e-10 40.9 0.9 3.5e-10 39.7 0.6 1.6 1 0 0 1 1 1 1 GAT domain FolB PF02152.13 EKG12834.1 - 1.2e-07 31.8 0.0 1.4e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroneopterin aldolase TPR_MLP1_2 PF07926.7 EKG12835.1 - 0.002 17.8 38.3 0.0031 17.2 11.6 19.1 1 1 14 19 19 19 8 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 EKG12835.1 - 0.0046 16.5 1.5 0.0046 16.5 1.0 20.6 2 2 15 20 20 20 7 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 EKG12835.1 - 0.005 16.6 8.6 0.005 16.6 5.9 20.1 1 1 20 21 21 21 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1556 PF07590.6 EKG12836.1 - 0.061 13.5 1.8 0.12 12.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) Pkinase PF00069.20 EKG12837.1 - 2.4e-72 243.1 0.0 4e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12837.1 - 5.7e-45 153.3 0.0 9.2e-45 152.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EKG12837.1 - 3.1e-19 69.1 0.4 3.1e-19 69.1 0.3 2.9 4 0 0 4 4 4 1 P21-Rho-binding domain Kinase-like PF14531.1 EKG12837.1 - 5.2e-07 28.9 0.0 9e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG12837.1 - 0.038 13.7 4.5 0.37 10.4 0.0 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EKG12837.1 - 0.059 12.4 0.2 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PNP_UDP_1 PF01048.15 EKG12838.1 - 2.6e-36 124.7 0.0 3.2e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PAP2 PF01569.16 EKG12839.1 - 2.4e-22 78.9 3.2 2.4e-22 78.9 2.2 1.8 2 1 0 2 2 2 1 PAP2 superfamily Polysacc_synt_C PF14667.1 EKG12839.1 - 0.43 10.3 11.2 2 8.1 1.3 3.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain PAP2_C PF14360.1 EKG12839.1 - 0.88 9.8 3.0 0.46 10.7 0.3 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Exo_endo_phos PF03372.18 EKG12840.1 - 1.3e-05 25.2 1.1 2.1e-05 24.5 0.8 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 EKG12840.1 - 0.00078 19.3 0.1 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain Tannase PF07519.6 EKG12841.1 - 4.8e-46 157.4 0.3 5.7e-46 157.1 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EKG12841.1 - 7.9e-05 22.6 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG12841.1 - 0.0028 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG12841.1 - 0.0067 15.6 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Fer4_6 PF12837.2 EKG12842.1 - 2 8.4 5.3 8.7 6.4 3.7 2.0 1 1 0 1 1 1 0 4Fe-4S binding domain Ferric_reduct PF01794.14 EKG12843.1 - 8.9e-05 22.5 5.9 0.00028 20.9 4.1 2.0 1 1 0 1 1 1 1 Ferric reductase like transmembrane component DUF4401 PF14351.1 EKG12843.1 - 0.18 10.7 8.2 0.034 13.1 1.6 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4401) zf-C2H2_2 PF12756.2 EKG12844.1 - 3e-34 117.1 13.5 1.2e-28 99.1 2.2 3.3 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EKG12844.1 - 2.4e-11 43.4 11.9 2.5e-06 27.4 2.6 4.0 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG12844.1 - 1.1e-06 28.6 10.6 1.6e-06 28.0 1.7 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EKG12844.1 - 0.00065 19.8 21.4 0.46 10.9 0.1 5.1 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-Di19 PF05605.7 EKG12844.1 - 0.0059 16.6 8.6 1.7 8.8 0.2 3.7 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding DUF629 PF04780.7 EKG12844.1 - 0.03 12.8 0.3 0.03 12.8 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 EKG12844.1 - 0.041 13.8 12.2 0.17 11.7 1.0 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger Elf1 PF05129.8 EKG12844.1 - 0.1 12.3 6.1 4.9 6.9 0.0 3.8 4 0 0 4 4 4 0 Transcription elongation factor Elf1 like Cytochrome-c551 PF10643.4 EKG12844.1 - 0.2 10.9 0.4 0.33 10.1 0.3 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 zf-DBF PF07535.7 EKG12844.1 - 0.21 11.2 8.6 0.26 11.0 0.6 3.6 3 0 0 3 3 3 0 DBF zinc finger Mso1_Sec1_bdg PF14475.1 EKG12844.1 - 1.9 7.9 4.3 0.55 9.6 0.1 2.2 2 0 0 2 2 2 0 Sec1-binding region of Mso1 zf-C2H2_4 PF13894.1 EKG12844.1 - 3.2 8.2 17.2 0.59 10.5 0.5 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger C1_1 PF00130.17 EKG12844.1 - 8.9 6.1 8.4 54 3.6 0.1 3.8 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HECT PF00632.20 EKG12845.1 - 4.7e-69 232.9 0.0 6.6e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FUSC-like PF12805.2 EKG12846.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS AAA_12 PF13087.1 EKG12847.1 - 1.9e-31 108.9 0.0 3.4e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG12847.1 - 5.7e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EKG12847.1 - 5.5e-09 35.8 0.0 1.6e-06 27.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKG12847.1 - 1.2e-05 24.9 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain Viral_helicase1 PF01443.13 EKG12847.1 - 0.0029 17.1 0.0 16 4.9 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EKG12847.1 - 0.0049 16.5 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EKG12847.1 - 0.005 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family KaiC PF06745.8 EKG12847.1 - 0.0083 15.2 0.0 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 EKG12847.1 - 0.015 15.5 0.0 0.044 14.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EKG12847.1 - 0.024 14.7 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EKG12847.1 - 0.044 14.6 0.0 0.12 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG12847.1 - 0.05 13.5 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EKG12847.1 - 0.056 12.3 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EKG12847.1 - 0.069 13.0 0.0 0.29 11.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain DsrC PF04358.8 EKG12847.1 - 0.07 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 DsrC like protein NACHT PF05729.7 EKG12847.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EKG12847.1 - 0.099 12.3 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EKG12847.1 - 0.1 12.7 0.0 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EKG12847.1 - 0.13 11.9 0.0 0.54 9.9 0.0 2.1 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Amidohydro_4 PF13147.1 EKG12848.1 - 4.3e-10 40.0 5.4 5.8e-10 39.6 3.8 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EKG12848.1 - 8.3e-08 32.1 0.5 2.4e-07 30.5 0.3 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG12848.1 - 0.00075 19.2 0.1 0.0024 17.5 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family Glyco_hydro_71 PF03659.9 EKG12850.1 - 4e-32 111.1 6.4 5.5e-32 110.6 4.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Peptidase_C48 PF02902.14 EKG12852.1 - 0.0029 17.2 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Fungal_trans_2 PF11951.3 EKG12855.1 - 6.8e-06 24.9 0.5 1.5e-05 23.7 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 EKG12856.1 - 4.7e-55 186.5 8.6 4.7e-55 186.5 6.0 1.4 2 0 0 2 2 2 1 RTA1 like protein zf-DHHC PF01529.15 EKG12856.1 - 6.4 6.1 14.6 1.5 8.1 3.5 2.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF1685 PF07939.6 EKG12857.1 - 1.3 8.7 3.1 0.67 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) Semialdhyde_dhC PF02774.13 EKG12858.1 - 1e-40 139.5 0.0 1.3e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EKG12858.1 - 0.00027 21.2 0.0 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 EKG12858.1 - 0.0074 15.7 0.3 0.052 12.9 0.0 2.2 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GMC_oxred_C PF05199.8 EKG12859.1 - 1e-31 110.1 0.1 1.6e-31 109.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EKG12859.1 - 7.4e-28 97.5 0.0 2.4e-23 82.7 0.0 3.0 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG12859.1 - 0.006 15.4 0.1 0.015 14.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EKG12859.1 - 0.0063 16.5 0.2 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG12859.1 - 0.028 13.3 0.0 0.15 10.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amidohydro_1 PF01979.15 EKG12860.1 - 5.5e-10 39.4 0.0 1.1e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EKG12860.1 - 0.00015 21.1 0.1 0.00067 18.9 0.0 1.9 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG12860.1 - 0.0013 18.8 0.6 0.0034 17.4 0.4 1.7 1 1 0 1 1 1 1 Amidohydrolase zf-RING_4 PF14570.1 EKG12862.1 - 5.2e-20 70.7 12.8 9.1e-20 69.9 8.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EKG12862.1 - 1.1e-07 31.3 0.0 3.5e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EKG12862.1 - 6.8e-06 25.6 7.1 1.4e-05 24.6 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 EKG12862.1 - 8.4e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EKG12862.1 - 0.00014 21.1 2.2 0.00014 21.1 1.5 3.1 3 1 0 3 3 2 1 Rtf2 RING-finger RRM_6 PF14259.1 EKG12862.1 - 0.00063 19.6 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EKG12862.1 - 0.00073 19.2 4.6 0.0013 18.4 3.2 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) DUF605 PF04652.11 EKG12862.1 - 0.0018 17.7 19.0 0.0018 17.7 13.2 2.9 2 1 0 2 2 1 1 Vta1 like FYVE_2 PF02318.11 EKG12862.1 - 0.0035 17.2 2.8 0.0035 17.2 2.0 1.8 2 0 0 2 2 1 1 FYVE-type zinc finger FYVE PF01363.16 EKG12862.1 - 0.018 14.9 2.6 0.039 13.8 1.8 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-UDP PF14569.1 EKG12862.1 - 0.09 12.5 2.8 0.21 11.3 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger SET_assoc PF11767.3 EKG12862.1 - 0.17 11.1 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-C3HC4 PF00097.20 EKG12862.1 - 0.2 11.3 11.2 0.45 10.2 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG12862.1 - 0.36 10.8 11.1 0.64 10.0 7.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.14 EKG12863.1 - 1.2e-35 121.7 0.0 1.8e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit CorA PF01544.13 EKG12864.1 - 1.6e-12 47.0 0.1 1.2e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Glyco_hydro_15 PF00723.16 EKG12865.1 - 2.4e-107 359.3 0.3 3e-107 358.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EKG12865.1 - 4.9e-32 109.4 0.3 1.1e-31 108.2 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain zf-CHY PF05495.7 EKG12866.1 - 2.7e-19 69.0 30.6 4.3e-18 65.2 11.0 3.3 3 0 0 3 3 3 3 CHY zinc finger DUF3295 PF11702.3 EKG12867.1 - 3.3e-135 451.9 41.6 3.9e-135 451.7 28.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EKG12867.1 - 1.4e-12 46.9 2.5 2.6e-12 46.0 1.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CENP-B_dimeris PF09026.5 EKG12867.1 - 0.62 10.3 10.7 1.8 8.8 7.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cep57_MT_bd PF06657.8 EKG12868.1 - 1.8e-19 69.4 0.0 1.8e-19 69.4 0.0 6.0 7 0 0 7 7 7 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EKG12868.1 - 1e-10 41.3 11.8 1e-10 41.3 8.2 5.8 2 1 3 5 5 5 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 EKG12868.1 - 0.082 12.6 28.7 0.14 11.9 1.0 6.1 5 1 1 6 6 6 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 EKG12868.1 - 0.14 11.9 7.4 0.028 14.1 1.0 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain NUP PF06516.6 EKG12869.1 - 1.1e-122 408.8 0.3 1.3e-104 349.4 0.0 2.7 3 0 0 3 3 3 2 Purine nucleoside permease (NUP) Pkinase PF00069.20 EKG12870.1 - 7.7e-45 153.0 0.0 8.8e-44 149.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG12870.1 - 6.1e-30 104.1 0.0 1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG12870.1 - 2.9e-06 26.4 0.0 5.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG12870.1 - 0.0044 16.1 0.1 0.0084 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG12870.1 - 0.017 14.8 0.7 0.12 12.1 0.1 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Cutinase PF01083.17 EKG12871.1 - 3e-26 92.2 0.2 1.9e-12 47.2 0.0 2.1 1 1 1 2 2 2 2 Cutinase Ric8 PF10165.4 EKG12872.1 - 8.8e-123 410.4 0.0 1e-122 410.2 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 EKG12873.1 - 2.4e-104 349.2 1.0 3.9e-104 348.5 0.1 1.7 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Aldose_epim PF01263.15 EKG12874.1 - 1e-41 142.9 0.0 1.5e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase adh_short PF00106.20 EKG12875.1 - 1.1e-16 61.2 0.0 2.4e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG12875.1 - 5.8e-14 52.4 0.0 3.6e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG12875.1 - 4.9e-05 23.0 0.0 0.00035 20.2 0.0 2.4 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 EKG12876.1 - 2e-06 26.7 15.1 2.7e-06 26.3 10.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.19 EKG12878.1 - 1.5e-12 47.1 1.0 1.8e-12 46.8 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase MFS_1 PF07690.11 EKG12879.1 - 7.7e-43 146.5 46.3 2.8e-42 144.7 32.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2149 PF09919.4 EKG12879.1 - 0.26 11.3 3.4 0.89 9.6 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Fungal_trans PF04082.13 EKG12880.1 - 1.3e-20 73.3 0.1 1.9e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG12880.1 - 1.9e-08 34.0 15.5 2.9e-08 33.4 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EKG12882.1 - 1.2e-22 80.6 0.6 5.7e-22 78.4 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG12882.1 - 4.2e-09 36.3 0.1 1.8e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EKG12882.1 - 1e-08 35.2 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 EKG12882.1 - 0.00083 18.9 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EKG12882.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EKG12882.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG12882.1 - 0.039 13.9 0.0 0.48 10.4 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Epimerase PF01370.16 EKG12882.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EKG12882.1 - 0.13 11.4 0.0 0.27 10.3 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EKG12882.1 - 0.14 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sugar_tr PF00083.19 EKG12883.1 - 3.1e-74 250.1 10.6 3.6e-74 249.9 7.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG12883.1 - 3e-10 39.3 21.7 1.3e-08 33.9 13.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 EKG12884.1 - 4.4e-26 92.1 0.0 8.9e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG12884.1 - 2.6e-21 76.2 0.3 4.9e-21 75.3 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans_2 PF11951.3 EKG12884.1 - 3.6e-13 48.8 0.1 9.1e-11 40.9 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain KR PF08659.5 EKG12884.1 - 3.3e-11 43.1 0.2 6.3e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 KR domain Peptidase_S10 PF00450.17 EKG12885.1 - 3e-52 178.2 0.0 3.6e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Acyl-CoA_dh_M PF02770.14 EKG12886.1 - 8.6e-08 31.5 0.2 2.3e-07 30.2 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF330 PF03886.8 EKG12886.1 - 0.018 14.4 1.4 0.045 13.1 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF330) Acyl-CoA_dh_1 PF00441.19 EKG12886.1 - 0.095 12.8 0.9 0.21 11.7 0.6 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1628 PF07790.6 EKG12887.1 - 0.031 15.0 1.2 0.11 13.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) SoxE PF06525.6 EKG12887.1 - 0.071 12.3 3.0 0.067 12.4 0.9 1.8 2 0 0 2 2 2 0 Sulfocyanin (SoxE) Myosin_head PF00063.16 EKG12887.1 - 0.17 9.9 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) HECT PF00632.20 EKG12888.1 - 9.2e-83 278.0 0.0 1.7e-82 277.0 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EKG12888.1 - 7.6e-06 25.5 1.2 1.9 8.4 0.0 5.8 5 1 1 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EKG12888.1 - 0.0016 18.3 3.6 0.14 12.2 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 EKG12888.1 - 0.02 13.2 5.3 1.1 7.4 0.0 3.8 3 1 0 4 4 4 0 Adaptin N terminal region Proteasom_PSMB PF10508.4 EKG12888.1 - 0.022 13.0 0.1 0.072 11.3 0.0 1.9 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit CTP_transf_2 PF01467.21 EKG12889.1 - 2.5e-29 102.3 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase Cellulase PF00150.13 EKG12890.1 - 1.2e-13 50.9 2.3 1.2e-13 50.9 1.6 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 EKG12890.1 - 0.059 13.2 0.0 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) ABC2_membrane_2 PF12679.2 EKG12890.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1510 PF07423.6 EKG12890.1 - 0.22 10.8 0.1 0.22 10.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Glyco_hydro_31 PF01055.21 EKG12891.1 - 9.9e-108 360.7 3.7 2.3e-107 359.5 2.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG12891.1 - 1.9e-05 24.4 2.3 1.9e-05 24.4 1.6 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like FG-GAP PF01839.18 EKG12892.1 - 5.1e-06 26.0 7.7 0.029 14.0 0.8 3.5 3 0 0 3 3 3 2 FG-GAP repeat VCBS PF13517.1 EKG12892.1 - 3.2e-05 24.1 10.6 0.053 13.8 3.0 4.0 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EKG12892.1 - 0.016 14.6 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/N-terminal region ALIX_LYPXL_bnd PF13949.1 EKG12894.1 - 0.12 11.3 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA PF00004.24 EKG12895.1 - 1.2e-20 74.0 0.0 2.8e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EKG12895.1 - 0.00012 21.6 0.1 0.0043 16.5 0.0 2.4 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EKG12895.1 - 0.00033 20.8 0.2 0.015 15.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG12895.1 - 0.00043 20.3 0.5 0.0015 18.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EKG12895.1 - 0.008 15.9 0.0 0.02 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EKG12895.1 - 0.011 16.5 0.1 0.026 15.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EKG12895.1 - 0.012 15.1 0.0 0.058 12.8 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EKG12895.1 - 0.026 14.1 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 EKG12895.1 - 0.033 13.6 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 EKG12895.1 - 0.055 13.2 0.2 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain Carboxyl_trans PF01039.17 EKG12896.1 - 7.2e-75 252.2 0.0 9.6e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EKG12897.1 - 9.9e-54 181.8 0.0 1.3e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EKG12897.1 - 7.3e-26 90.4 0.0 3.5e-25 88.2 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EKG12897.1 - 5.7e-17 62.0 0.0 1.3e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG12897.1 - 1e-16 60.6 0.0 9.3e-12 44.3 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_carb_C PF02785.14 EKG12897.1 - 5.6e-13 48.8 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.8 EKG12897.1 - 3.9e-07 29.6 0.0 5.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EKG12897.1 - 8.2e-07 28.5 0.0 1.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EKG12897.1 - 1.7e-05 24.3 0.0 9.8e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EKG12897.1 - 0.00011 22.0 0.0 0.00057 19.7 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 EKG12897.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.4 1 1 0 1 1 1 0 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.11 EKG12897.1 - 0.03 13.4 0.0 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_YheCD PF14398.1 EKG12897.1 - 0.22 10.2 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 YheC/D like ATP-grasp adh_short PF00106.20 EKG12898.1 - 2e-30 105.8 1.3 3.1e-30 105.2 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG12898.1 - 6.6e-29 101.3 0.1 8.7e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG12898.1 - 2.4e-14 53.3 0.5 3.7e-14 52.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG12898.1 - 1.5e-05 24.5 0.1 2.4e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF500 PF04366.7 EKG12899.1 - 5.6e-45 151.8 0.2 9.7e-45 151.0 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EKG12899.1 - 3.3e-14 51.9 0.5 8e-14 50.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EKG12899.1 - 3e-12 45.8 0.0 8.1e-12 44.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EKG12899.1 - 1.4e-10 40.5 0.1 2.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Fungal_trans_2 PF11951.3 EKG12901.1 - 2.1e-07 29.8 0.1 2.5e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EKG12903.1 - 8e-09 35.0 0.0 1.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EKG12903.1 - 2e-05 23.7 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EKG12903.1 - 0.00055 19.9 0.0 0.001 19.1 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Bac_luciferase PF00296.15 EKG12904.1 - 1.7e-17 63.5 0.1 1.9e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidase PF01425.16 EKG12905.1 - 1.8e-81 274.2 0.0 2.4e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 EKG12906.1 - 0.0027 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG12906.1 - 0.0069 17.2 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Slx4 PF09494.5 EKG12907.1 - 4.1e-15 55.2 0.4 2.5e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 Slx4 endonuclease Pyr_redox_2 PF07992.9 EKG12908.1 - 1e-06 28.8 0.0 4.1e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG12908.1 - 0.00019 21.2 0.0 0.014 15.1 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EKG12908.1 - 0.00043 19.2 0.3 0.0012 17.8 0.3 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG12908.1 - 0.0042 17.1 0.1 0.025 14.6 0.1 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EKG12908.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain CPSase_L_chain PF00289.17 EKG12908.1 - 0.031 14.3 0.0 0.095 12.8 0.0 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 EKG12908.1 - 0.095 11.6 0.1 0.27 10.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Sugar_tr PF00083.19 EKG12911.1 - 5.6e-92 308.6 24.2 6.6e-92 308.4 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Bac_rhamnosid PF05592.6 EKG12911.1 - 5.2e-22 77.7 0.0 5e-13 48.0 0.0 2.2 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase MFS_1 PF07690.11 EKG12911.1 - 1e-13 50.7 36.8 6.1e-11 41.6 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EKG12913.1 - 1e-63 215.5 0.0 1.3e-63 215.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Smr PF01713.16 EKG12914.1 - 6.8e-13 48.6 0.3 1.4e-12 47.5 0.2 1.6 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EKG12914.1 - 6.9e-06 25.4 0.0 0.0015 17.9 0.0 2.6 2 0 0 2 2 2 2 CUE domain DUF1771 PF08590.5 EKG12914.1 - 0.4 10.7 5.5 1.1 9.3 3.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Chromo PF00385.19 EKG12915.1 - 1.1e-11 44.2 0.6 1.1e-11 44.2 0.4 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EKG12915.1 - 2.6e-07 30.3 0.6 1.2e-06 28.2 0.1 2.1 2 1 0 2 2 2 1 Chromo shadow domain Cpn60_TCP1 PF00118.19 EKG12916.1 - 2e-146 488.4 2.9 2.2e-146 488.2 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 EKG12916.1 - 0.016 14.8 0.1 0.38 10.3 0.0 2.7 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ENTH PF01417.15 EKG12917.1 - 5.8e-21 74.6 0.4 9.1e-21 74.0 0.3 1.3 1 0 0 1 1 1 1 ENTH domain Pro_isomerase PF00160.16 EKG12918.1 - 8.3e-40 136.5 0.4 9.6e-40 136.3 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cys_Met_Meta_PP PF01053.15 EKG12919.1 - 6.6e-62 209.0 0.0 1.9e-61 207.4 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EKG12919.1 - 0.0011 17.7 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EKG12919.1 - 0.074 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF1476 PF07345.6 EKG12919.1 - 0.12 12.6 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1476) zf-C2H2 PF00096.21 EKG12920.1 - 0.00092 19.4 2.6 0.028 14.7 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG12920.1 - 0.00098 19.3 1.8 0.043 14.1 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG12920.1 - 0.034 14.2 0.6 12 6.2 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EKG12920.1 - 0.22 11.6 1.3 4.3 7.5 0.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SIMPL PF04402.9 EKG12920.1 - 9.3 6.0 8.5 24 4.7 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF541) UDPGP PF01704.13 EKG12922.1 - 1.7e-182 606.6 0.2 1.9e-182 606.4 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 EKG12922.1 - 0.033 12.7 0.1 0.033 12.7 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) IBN_N PF03810.14 EKG12923.1 - 7.1e-14 51.4 0.0 1e-12 47.8 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 EKG12923.1 - 6.1e-05 21.7 0.6 0.00019 20.1 0.2 1.9 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.7 EKG12923.1 - 6.2e-05 22.9 0.8 0.0077 16.1 0.0 3.2 2 0 0 2 2 2 1 Exportin 1-like protein TPR_11 PF13414.1 EKG12924.1 - 3.4e-60 199.6 24.1 2.2e-18 65.6 0.6 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EKG12924.1 - 3.2e-46 153.1 21.3 6.9e-06 25.4 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EKG12924.1 - 5.5e-36 119.5 27.0 0.00019 21.0 0.0 10.1 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EKG12924.1 - 5.7e-22 77.4 10.8 1.9e-10 40.5 0.1 5.7 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKG12924.1 - 4.6e-20 71.7 16.1 0.0023 18.5 0.0 6.9 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EKG12924.1 - 1.1e-19 69.0 14.8 0.015 15.9 0.1 9.2 6 3 3 10 10 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EKG12924.1 - 1.6e-18 65.0 18.4 0.0037 16.9 0.1 8.0 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 EKG12924.1 - 1.8e-15 57.0 16.8 0.014 15.7 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EKG12924.1 - 8.1e-13 47.4 11.1 0.03 14.4 0.1 8.6 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKG12924.1 - 6.5e-11 41.1 14.7 0.0044 16.7 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG12924.1 - 2.4e-09 36.8 3.7 0.0023 17.7 0.3 5.4 4 2 2 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG12924.1 - 6.6e-08 32.5 10.1 0.023 14.8 0.9 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKG12924.1 - 8e-07 29.1 21.2 0.78 10.3 0.0 8.7 9 0 0 9 9 7 1 Tetratricopeptide repeat MIT PF04212.13 EKG12924.1 - 0.021 14.7 29.5 1.1 9.1 1.8 7.2 6 2 3 9 9 9 0 MIT (microtubule interacting and transport) domain PPR_2 PF13041.1 EKG12924.1 - 0.066 13.2 0.4 1.2e+02 2.7 0.0 4.4 4 0 0 4 4 4 0 PPR repeat family TPR_10 PF13374.1 EKG12924.1 - 0.075 12.9 3.3 27 4.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Inhibitor_I9 PF05922.11 EKG12924.1 - 0.087 13.3 0.1 0.37 11.3 0.1 2.1 1 0 0 1 1 1 0 Peptidase inhibitor I9 TPR_3 PF07720.7 EKG12924.1 - 1 9.2 18.2 6.5 6.6 0.3 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Trypan_PARP PF05887.6 EKG12924.1 - 6.5 6.5 19.1 23 4.7 13.2 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spc7 PF08317.6 EKG12925.1 - 0.0045 15.6 8.7 0.0084 14.8 6.0 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.1 EKG12925.1 - 0.075 11.4 9.7 0.14 10.6 6.7 1.4 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.8 EKG12925.1 - 0.32 10.0 1.3 0.65 9.0 0.9 1.4 1 0 0 1 1 1 0 TMPIT-like protein KxDL PF10241.4 EKG12925.1 - 0.45 10.4 5.9 14 5.6 1.3 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein AATF-Che1 PF13339.1 EKG12925.1 - 0.47 10.6 7.5 0.92 9.6 3.5 2.7 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Pex14_N PF04695.8 EKG12925.1 - 0.47 10.4 17.6 0.58 10.2 5.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lebercilin PF15619.1 EKG12925.1 - 0.49 9.7 19.1 1.7 8.0 7.8 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Suf PF05843.9 EKG12925.1 - 0.75 9.4 5.2 2.2 7.9 1.0 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TMCO5 PF14992.1 EKG12925.1 - 1.4 7.9 9.3 2.6 7.1 6.4 1.5 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.14 EKG12925.1 - 2.5 5.8 4.2 4 5.1 2.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EKG12925.1 - 4.4 7.3 18.0 0.4 10.7 7.2 3.0 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Rho_Binding PF08912.6 EKG12925.1 - 7.6 6.9 12.3 6.4 7.1 2.0 3.1 2 0 0 2 2 2 0 Rho Binding IncA PF04156.9 EKG12925.1 - 7.7 6.0 19.6 8.9e+02 -0.7 13.6 2.7 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 EKG12925.1 - 8.2 6.2 23.3 0.077 12.8 7.3 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_hydro_76 PF03663.9 EKG12926.1 - 1e-20 74.4 9.8 3e-09 36.7 0.0 4.5 3 2 0 3 3 3 3 Glycosyl hydrolase family 76 RRM_1 PF00076.17 EKG12927.1 - 4.1e-16 58.3 0.0 7.4e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG12927.1 - 5.5e-12 45.4 0.0 9.8e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG12927.1 - 5.2e-06 26.2 0.0 7.3e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKG12927.1 - 0.13 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif Ribonuc_L-PSP PF01042.16 EKG12928.1 - 1.8e-37 127.7 0.0 2e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pribosyltran PF00156.22 EKG12929.1 - 8.9e-18 64.2 0.0 1.3e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EKG12929.1 - 0.0024 17.1 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EKG12929.1 - 0.12 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 PRTase ComF-like AAA PF00004.24 EKG12930.1 - 1.3e-18 67.4 0.0 2.6e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG12930.1 - 0.00022 21.3 0.6 0.0076 16.3 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG12930.1 - 0.00048 20.9 0.0 0.0052 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EKG12930.1 - 0.00063 18.8 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EKG12930.1 - 0.0018 18.6 0.1 0.012 15.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EKG12930.1 - 0.0062 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EKG12930.1 - 0.036 13.9 0.0 0.084 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG12930.1 - 0.037 14.0 0.2 0.12 12.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Vps36_ESCRT-II PF11605.3 EKG12930.1 - 0.041 13.6 0.1 0.2 11.4 0.0 2.2 3 0 0 3 3 3 0 Vacuolar protein sorting protein 36 Vps36 IstB_IS21 PF01695.12 EKG12930.1 - 0.043 13.2 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EKG12930.1 - 0.13 11.3 0.1 2.5 7.1 0.1 2.2 2 0 0 2 2 2 0 KaiC C2 PF00168.25 EKG12931.1 - 3.2e-66 219.1 2.0 1.5e-18 66.4 0.0 6.3 6 0 0 6 6 6 5 C2 domain TFR_dimer PF04253.10 EKG12932.1 - 8.9e-17 60.8 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EKG12932.1 - 6.5e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EKG12932.1 - 4.8e-06 26.1 0.2 2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 PA domain zf-IS66 PF13005.2 EKG12933.1 - 0.00036 20.4 1.8 0.28 11.1 0.2 2.2 2 0 0 2 2 2 2 zinc-finger binding domain of transposase IS66 6PGD PF00393.14 EKG12934.1 - 2e-74 250.4 0.2 2.3e-74 250.2 0.1 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EKG12934.1 - 2.7e-23 82.5 0.0 6.5e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EKG12934.1 - 0.021 14.9 0.0 0.041 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pex2_Pex12 PF04757.9 EKG12935.1 - 4.5e-41 140.7 3.4 6.9e-41 140.1 2.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EKG12935.1 - 0.0016 18.2 4.6 0.0029 17.4 3.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EKG12935.1 - 0.32 10.7 2.1 0.24 11.1 0.2 1.8 2 0 0 2 2 2 0 RING-type zinc-finger Na_trans_assoc PF06512.8 EKG12935.1 - 0.64 9.9 5.8 0.4 10.6 0.1 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated zf-C3HC4_2 PF13923.1 EKG12935.1 - 1.7 8.7 9.4 0.13 12.3 2.6 2.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF753 PF05444.7 EKG12937.1 - 0.086 12.7 1.8 0.089 12.6 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF753) DUF2094 PF09867.4 EKG12938.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) Acyl-CoA_dh_M PF02770.14 EKG12940.1 - 0.017 14.5 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain ABC_tran PF00005.22 EKG12941.1 - 1.7e-44 151.4 0.0 4e-26 91.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKG12941.1 - 2.6e-35 122.1 21.5 5.1e-17 62.1 6.9 3.3 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EKG12941.1 - 1.2e-14 54.0 0.0 0.00069 18.9 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG12941.1 - 2.9e-11 43.8 0.1 0.0016 18.5 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EKG12941.1 - 5.7e-08 32.9 6.3 0.00076 19.5 0.2 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.1 EKG12941.1 - 8.1e-08 32.8 0.1 0.0015 18.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKG12941.1 - 4.3e-07 29.5 0.0 0.0026 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EKG12941.1 - 1.2e-06 27.6 0.0 0.034 13.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EKG12941.1 - 1.6e-06 28.2 0.1 0.04 14.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKG12941.1 - 2.3e-06 27.0 1.0 0.0038 16.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EKG12941.1 - 5.9e-06 25.9 0.1 0.12 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain DUF258 PF03193.11 EKG12941.1 - 1.3e-05 24.4 0.0 0.028 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 EKG12941.1 - 4.7e-05 23.1 1.2 0.19 11.4 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 EKG12941.1 - 5.2e-05 22.0 0.2 0.025 13.2 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 EKG12941.1 - 6.3e-05 22.5 0.0 0.0069 15.8 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EKG12941.1 - 0.00014 22.6 0.2 0.072 13.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EKG12941.1 - 0.00016 22.1 0.2 0.062 13.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 EKG12941.1 - 0.00022 20.9 2.8 0.26 10.9 0.3 2.8 2 1 0 2 2 2 2 NACHT domain cobW PF02492.14 EKG12941.1 - 0.00022 20.7 0.3 0.11 11.9 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EKG12941.1 - 0.00023 21.0 0.1 0.0047 16.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 EKG12941.1 - 0.00042 19.9 0.5 1 8.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EKG12941.1 - 0.0005 19.7 5.1 0.11 12.2 0.1 3.3 3 0 0 3 3 2 2 Part of AAA domain MMR_HSR1 PF01926.18 EKG12941.1 - 0.00069 19.5 0.1 0.12 12.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NB-ARC PF00931.17 EKG12941.1 - 0.0013 17.6 0.4 0.32 9.7 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 EKG12941.1 - 0.0024 18.1 0.0 0.53 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKG12941.1 - 0.0025 16.9 0.4 0.95 8.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EKG12941.1 - 0.0053 16.6 0.1 3.2 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EKG12941.1 - 0.0066 16.6 0.0 1.2 9.3 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKG12941.1 - 0.0071 16.0 0.1 0.27 10.8 0.0 2.7 3 0 0 3 3 3 1 Archaeal ATPase Pox_A32 PF04665.7 EKG12941.1 - 0.0079 15.5 0.1 2.4 7.3 0.0 2.2 2 0 0 2 2 2 1 Poxvirus A32 protein Dynamin_N PF00350.18 EKG12941.1 - 0.012 15.4 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ABC_ATPase PF09818.4 EKG12941.1 - 0.024 13.2 0.3 1.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PhoH PF02562.11 EKG12941.1 - 0.03 13.5 0.1 8.2 5.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_15 PF13175.1 EKG12941.1 - 0.035 13.1 0.0 0.079 11.9 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain Sigma54_activat PF00158.21 EKG12941.1 - 0.04 13.3 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 EKG12941.1 - 0.059 12.4 0.2 0.98 8.4 0.0 2.3 2 0 0 2 2 2 0 KaiC SbcCD_C PF13558.1 EKG12941.1 - 0.06 13.2 0.0 14 5.6 0.0 3.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EKG12941.1 - 0.062 12.7 0.6 3.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EKG12941.1 - 0.091 12.3 1.1 4.1 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EKG12941.1 - 0.12 12.1 0.4 16 5.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EKG12941.1 - 0.12 11.3 1.5 4.9 6.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EKG12941.1 - 0.17 12.0 0.0 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EKG12941.1 - 0.19 11.6 0.0 18 5.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EKG12941.1 - 0.22 11.2 1.5 10 5.7 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 EKG12941.1 - 0.23 10.9 0.0 7.3 6.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain ATP-synt_ab PF00006.20 EKG12941.1 - 0.31 10.5 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Adeno_IVa2 PF02456.10 EKG12941.1 - 0.46 9.0 0.0 8.2 4.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Septin PF00735.13 EKG12941.1 - 0.52 9.2 0.9 16 4.3 0.0 2.7 3 0 0 3 3 3 0 Septin ArgK PF03308.11 EKG12941.1 - 1.2 7.9 4.4 0.49 9.1 0.2 2.3 3 0 0 3 3 3 0 ArgK protein DUF3543 PF12063.3 EKG12943.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) adh_short PF00106.20 EKG12945.1 - 1.1e-31 110.0 3.9 1.1e-31 110.0 2.7 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG12945.1 - 7.1e-22 78.3 1.6 9.3e-22 77.9 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG12945.1 - 2e-08 34.1 1.5 2e-08 34.1 1.0 1.8 1 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EKG12945.1 - 5.2e-06 26.0 0.1 8.1e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG12945.1 - 3.2e-05 22.9 0.0 5.7e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EKG12945.1 - 0.0003 20.4 0.2 0.00057 19.5 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 EKG12945.1 - 0.0031 16.7 0.2 0.0061 15.8 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EKG12945.1 - 0.0033 17.4 0.4 0.0066 16.4 0.1 1.7 2 0 0 2 2 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EKG12945.1 - 0.0033 17.4 0.6 0.0083 16.1 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG12945.1 - 0.0035 16.1 0.1 0.0046 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EKG12945.1 - 0.0058 17.0 0.8 0.17 12.3 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EKG12945.1 - 0.013 15.2 0.3 0.041 13.6 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EKG12945.1 - 0.018 13.9 0.1 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 EKG12945.1 - 0.019 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EKG12945.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EKG12945.1 - 0.035 13.2 0.1 0.063 12.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 EKG12945.1 - 0.04 13.5 0.3 0.1 12.2 0.2 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AdoHcyase_NAD PF00670.16 EKG12945.1 - 0.054 13.3 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 EKG12945.1 - 0.074 12.1 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LytR_C PF13399.1 EKG12945.1 - 0.13 12.6 1.2 0.21 12.0 0.1 1.9 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator DUF4246 PF14033.1 EKG12946.1 - 9.2e-176 585.3 0.0 1.1e-175 585.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EKG12946.1 - 0.027 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2-Hacid_dh_C PF02826.14 EKG12947.1 - 8.3e-39 132.5 0.0 2.5e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG12947.1 - 7.4e-22 77.2 0.0 8.4e-22 77.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 EKG12947.1 - 0.00013 21.4 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 EKG12947.1 - 0.008 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 EKG12947.1 - 0.013 15.3 0.0 0.045 13.5 0.0 1.9 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 EKG12947.1 - 0.026 14.9 0.3 0.11 12.9 0.1 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EKG12947.1 - 0.026 14.5 0.2 0.078 12.9 0.0 1.9 2 1 0 2 2 2 0 NADH(P)-binding DUF374 PF04028.8 EKG12947.1 - 0.03 13.5 0.2 0.49 9.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF374) AlaDh_PNT_C PF01262.16 EKG12947.1 - 0.035 13.6 1.7 8.9 5.8 0.1 3.1 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EKG12947.1 - 0.05 13.2 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EKG12947.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EKG12948.1 - 2.9e-20 72.8 0.0 5.2e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG12948.1 - 4.1e-14 52.9 0.0 5.1e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG12948.1 - 3.8e-08 33.2 0.0 2.9e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG12948.1 - 0.0084 15.5 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG12948.1 - 0.011 15.4 0.2 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 7kD_coat PF02495.12 EKG12948.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 7kD viral coat protein p450 PF00067.17 EKG12949.1 - 3.6e-59 200.5 0.0 4.7e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EKG12950.1 - 9.3e-27 93.6 19.1 9.3e-27 93.6 13.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG12950.1 - 1.1e-08 33.7 1.2 2.2e-08 32.7 0.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 EKG12951.1 - 5.1e-73 245.8 0.0 7.1e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG12951.1 - 2.6e-10 41.0 0.2 6.8e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TauD PF02668.11 EKG12952.1 - 1.8e-51 175.3 0.1 2.9e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_16 PF00722.16 EKG12952.1 - 1.2e-38 132.2 4.7 1.9e-38 131.5 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 2OG-FeII_Oxy_4 PF13661.1 EKG12952.1 - 0.23 11.1 2.7 0.21 11.2 0.4 2.0 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF2393 PF09624.5 EKG12954.1 - 0.22 11.0 1.1 0.41 10.1 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) Kinesin PF00225.18 EKG12957.1 - 6.1e-115 383.4 0.0 9.4e-115 382.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain IncA PF04156.9 EKG12957.1 - 0.099 12.2 0.9 0.23 11.0 0.6 1.5 1 0 0 1 1 1 0 IncA protein Synaptobrevin PF00957.16 EKG12957.1 - 0.18 11.4 2.5 0.46 10.1 1.7 1.6 1 0 0 1 1 1 0 Synaptobrevin Herpes_UL14 PF03580.9 EKG12957.1 - 1.1 9.0 10.1 2.1 8.1 5.4 2.4 2 1 0 2 2 2 0 Herpesvirus UL14-like protein ADH_N PF08240.7 EKG12959.1 - 3.3e-07 30.0 0.1 9.1e-07 28.6 0.1 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain G-gamma PF00631.17 EKG12960.1 - 0.88 9.3 3.6 2 8.2 2.5 1.6 1 0 0 1 1 1 0 GGL domain Ribosomal_L34e PF01199.13 EKG12961.1 - 5e-37 126.0 4.3 6.7e-37 125.6 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EKG12961.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Zn_ribbon_recom PF13408.1 EKG12961.1 - 0.049 13.8 0.2 0.049 13.8 0.2 1.9 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-ribbon_3 PF13248.1 EKG12961.1 - 0.35 10.1 2.1 0.73 9.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PROCN PF08083.6 EKG12962.1 - 2.5e-222 737.6 6.8 4.4e-222 736.8 4.7 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EKG12962.1 - 6.4e-127 421.5 2.0 1.1e-126 420.8 1.4 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EKG12962.1 - 2e-94 313.2 1.3 4.4e-94 312.1 0.9 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EKG12962.1 - 5.6e-78 259.8 4.2 8.4e-78 259.2 2.0 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EKG12962.1 - 1.3e-66 222.3 0.1 2.6e-66 221.3 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EKG12962.1 - 1.2e-46 157.4 0.2 4.8e-46 155.5 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EKG12962.1 - 5.8e-45 151.0 0.3 1.7e-44 149.5 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 OCD_Mu_crystall PF02423.10 EKG12962.1 - 0.014 14.2 1.2 0.024 13.3 0.9 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family DUF3753 PF12575.3 EKG12962.1 - 0.093 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) p450 PF00067.17 EKG12963.1 - 3.3e-12 45.6 0.0 4.3e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ATP_bind_2 PF03668.10 EKG12964.1 - 0.01 14.9 0.0 3.1 6.8 0.0 2.1 2 0 0 2 2 2 0 P-loop ATPase protein family Cortex-I_coil PF09304.5 EKG12964.1 - 0.13 12.3 1.7 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil Metal_resist PF13801.1 EKG12964.1 - 1 9.3 7.7 0.082 12.9 0.7 2.2 2 1 0 2 2 2 0 Heavy-metal resistance Malic_M PF03949.10 EKG12965.1 - 1.4e-81 273.8 0.2 1.8e-81 273.4 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EKG12965.1 - 3.6e-68 228.7 0.1 2.7e-67 225.8 0.0 2.1 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Fungal_trans PF04082.13 EKG12966.1 - 1.3e-07 30.7 0.0 2.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG12966.1 - 3.3e-06 26.8 10.9 6e-06 26.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 EKG12967.1 - 7.7e-87 291.6 19.3 7.9e-86 288.3 13.4 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EKG12967.1 - 2.1e-26 92.6 1.3 3.1e-26 92.1 0.9 1.2 1 0 0 1 1 1 1 ML-like domain DUF3754 PF12576.3 EKG12967.1 - 0.27 10.8 1.1 0.84 9.2 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) FYVE PF01363.16 EKG12968.1 - 3.1e-22 78.2 1.0 3.1e-22 78.2 0.7 2.7 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EKG12968.1 - 6.7e-09 35.4 23.8 1.1e-08 34.7 3.0 3.5 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EKG12968.1 - 0.00027 20.5 1.6 0.00027 20.5 1.1 3.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EKG12968.1 - 0.0034 17.2 0.6 0.0034 17.2 0.4 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger Elf1 PF05129.8 EKG12968.1 - 0.067 12.9 3.9 0.13 11.9 0.9 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Rad50_zn_hook PF04423.9 EKG12968.1 - 0.074 12.5 5.3 2.3 7.7 1.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-rbx1 PF12678.2 EKG12968.1 - 0.36 10.9 14.5 0.029 14.4 2.2 3.4 3 0 0 3 3 3 0 RING-H2 zinc finger TerY-C PF15616.1 EKG12968.1 - 0.36 10.7 6.5 0.68 9.8 2.0 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain RNB PF00773.14 EKG12969.1 - 1e-60 205.7 0.0 2.3e-60 204.6 0.0 1.6 1 0 0 1 1 1 1 RNB domain ThiS PF02597.15 EKG12970.1 - 1e-08 35.4 0.0 1.7e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 ThiS family MFS_1 PF07690.11 EKG12971.1 - 9.4e-42 142.9 21.3 8.9e-30 103.5 0.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG12971.1 - 8.8e-11 41.0 2.5 8.8e-11 41.0 1.7 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EKG12971.1 - 1.7e-05 23.4 1.6 1.7e-05 23.4 1.1 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 EKG12971.1 - 0.017 13.3 1.6 0.021 13.0 0.1 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EKG12971.1 - 0.043 11.9 7.2 0.022 12.9 0.6 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Amidohydro_1 PF01979.15 EKG12972.1 - 1.4e-32 113.6 0.0 1.9e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG12972.1 - 5.8e-17 62.6 1.9 5.2e-15 56.2 1.3 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EKG12972.1 - 5e-11 42.2 0.0 3e-10 39.7 0.0 2.3 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG12972.1 - 1.3e-09 37.8 2.3 1.1e-07 31.4 0.4 2.4 2 1 0 2 2 2 2 Amidohydrolase family DUF2462 PF09495.5 EKG12974.1 - 8.8e-20 71.2 14.4 1.1e-19 70.9 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) DUF2413 PF10310.4 EKG12975.1 - 5.6e-142 473.6 0.2 6.4e-142 473.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EKG12975.1 - 0.005 16.8 0.8 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 Influenza Matrix protein (M1) C-terminal domain IlvC PF01450.14 EKG12975.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain p450 PF00067.17 EKG12979.1 - 1.5e-23 83.1 0.0 2.8e-20 72.3 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 Abhydrolase_6 PF12697.2 EKG12980.1 - 4.3e-20 72.5 0.1 5.5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG12980.1 - 1.5e-18 66.9 0.0 2.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EKG12980.1 - 1e-09 38.2 0.0 1.1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EKG12980.1 - 1.6e-08 34.0 0.0 2.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 EKG12980.1 - 4.4e-08 31.9 0.0 1e-05 24.2 0.0 2.4 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EKG12980.1 - 4.8e-07 29.7 0.0 2.4e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EKG12980.1 - 9.3e-05 22.0 0.2 0.00017 21.2 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1100 PF06500.6 EKG12980.1 - 0.00055 18.6 0.0 0.0088 14.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) DLH PF01738.13 EKG12980.1 - 0.00073 18.8 0.0 0.0026 17.1 0.0 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EKG12980.1 - 0.0015 18.1 0.2 0.0061 16.1 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EKG12980.1 - 0.018 14.5 0.0 0.32 10.4 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 EKG12980.1 - 0.078 12.3 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase ketoacyl-synt PF00109.21 EKG12981.1 - 3.6e-28 98.7 0.0 4.4e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG12982.1 - 1.3e-54 185.7 0.0 2.5e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EKG12982.1 - 1.3e-48 165.6 0.0 2.8e-48 164.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EKG12982.1 - 2.8e-14 54.0 0.0 3.4e-13 50.6 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EKG12982.1 - 2.1e-12 46.7 0.0 1.2e-11 44.3 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ketoacyl-synt PF00109.21 EKG12982.1 - 1.8e-09 37.4 0.1 1.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ADH_N PF08240.7 EKG12982.1 - 3.9e-07 29.8 0.2 1e-06 28.4 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 EKG12982.1 - 0.013 15.1 0.0 0.042 13.5 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_7 PF03441.9 EKG12983.1 - 1.5e-97 326.1 2.0 1.8e-97 325.8 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EKG12983.1 - 1.8e-40 138.3 0.1 3e-40 137.6 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase Zn_clus PF00172.13 EKG12984.1 - 2.1e-07 30.7 10.2 2.1e-07 30.7 7.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_dh PF01619.13 EKG12985.1 - 1e-28 100.2 0.1 2e-28 99.2 0.1 1.4 1 1 0 1 1 1 1 Proline dehydrogenase Methyltransf_6 PF03737.10 EKG12986.1 - 3.7e-21 75.6 5.3 4.9e-21 75.1 3.7 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase SnoaL_4 PF13577.1 EKG12987.1 - 0.18 11.7 1.9 0.31 10.9 0.3 2.1 2 0 0 2 2 2 0 SnoaL-like domain P3A PF08727.6 EKG12987.1 - 0.32 10.3 2.7 0.4 10.0 0.0 2.5 3 0 0 3 3 3 0 Poliovirus 3A protein like Ribosomal_L14 PF00238.14 EKG12988.1 - 4e-32 110.5 0.0 4.6e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e MFS_1 PF07690.11 EKG12992.1 - 1.6e-11 43.5 21.1 1.6e-11 43.5 14.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EKG12992.1 - 2.7 7.5 0.0 2.7 7.5 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) MARVEL PF01284.18 EKG12993.1 - 0.027 14.3 17.8 0.012 15.3 8.9 2.0 1 1 1 2 2 2 0 Membrane-associating domain TMEM190 PF15431.1 EKG12993.1 - 1.1 9.1 3.0 0.57 10.1 0.2 1.9 2 0 0 2 2 2 0 Transmembrane protein 190 Cofilin_ADF PF00241.15 EKG12994.1 - 5.1e-11 42.5 0.0 5.5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NTP_transf_5 PF14907.1 EKG12994.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase MoCF_biosynth PF00994.19 EKG12995.1 - 1.4e-34 118.6 0.0 2.2e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EKG12996.1 - 9.5e-60 200.6 0.3 1.1e-59 200.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG12996.1 - 7e-19 68.4 0.0 9.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG12996.1 - 2e-08 33.6 0.0 2.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG12996.1 - 1.3e-07 31.2 0.2 7.6e-07 28.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EKG12996.1 - 0.00059 19.1 0.0 0.00097 18.4 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EKG12996.1 - 0.0021 17.9 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKG12996.1 - 0.036 13.2 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 EKG12996.1 - 0.046 13.1 0.6 0.71 9.2 0.1 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EKG12996.1 - 0.063 12.4 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 EKG12996.1 - 0.072 12.0 0.2 0.93 8.3 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ser_hydrolase PF06821.8 EKG12996.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.12 EKG12996.1 - 0.4 10.1 2.1 4.1 6.8 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Metallophos PF00149.23 EKG12998.1 - 1.1e-43 149.0 0.8 1.4e-43 148.6 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 EKG12998.1 - 0.11 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 cwf21 domain Methyltransf_3 PF01596.12 EKG12999.1 - 3.1e-35 121.0 0.0 4.1e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EKG12999.1 - 8.4e-14 52.2 0.3 1.7e-13 51.3 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG12999.1 - 7.9e-10 39.3 0.1 2.3e-09 37.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EKG12999.1 - 2e-06 27.3 0.2 4.2e-06 26.2 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EKG12999.1 - 2.3e-06 27.6 0.1 4.8e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EKG12999.1 - 0.0005 19.6 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 EKG12999.1 - 0.00068 19.2 0.0 0.00091 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EKG12999.1 - 0.0012 18.1 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase PCMT PF01135.14 EKG12999.1 - 0.0068 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF633 PF04816.7 EKG12999.1 - 0.013 14.8 0.1 0.026 13.8 0.1 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF633) CMAS PF02353.15 EKG12999.1 - 0.017 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EKG12999.1 - 0.02 14.4 0.1 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EKG12999.1 - 0.031 13.8 0.5 0.045 13.3 0.4 1.4 1 1 0 1 1 1 0 Met-10+ like-protein Mycobact_memb PF05423.8 EKG12999.1 - 0.05 13.3 0.1 0.099 12.3 0.1 1.6 1 1 0 1 1 1 0 Mycobacterium membrane protein Methyltransf_4 PF02390.12 EKG12999.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Fungal_trans_2 PF11951.3 EKG13000.1 - 0.0088 14.6 1.2 0.013 14.1 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FYVE_2 PF02318.11 EKG13002.1 - 0.00058 19.7 26.7 0.31 10.9 4.1 3.3 3 0 0 3 3 3 3 FYVE-type zinc finger zf-ribbon_3 PF13248.1 EKG13002.1 - 0.018 14.2 2.6 0.018 14.2 1.8 4.2 3 2 0 3 3 3 0 zinc-ribbon domain GET2 PF08690.5 EKG13002.1 - 0.13 11.5 0.5 0.19 10.9 0.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 zf-C3HC4 PF00097.20 EKG13002.1 - 0.59 9.8 39.3 0.086 12.5 5.4 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Selenoprotein_S PF06936.6 EKG13002.1 - 0.99 8.9 8.5 0.8 9.2 0.6 2.4 2 0 0 2 2 2 0 Selenoprotein S (SelS) POPLD PF08170.7 EKG13002.1 - 1.9 8.3 5.3 17 5.2 0.1 3.4 3 1 0 3 3 3 0 POPLD (NUC188) domain zf-RING_2 PF13639.1 EKG13003.1 - 2.2e-08 33.7 3.6 4e-08 32.9 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKG13003.1 - 1.2e-06 28.0 1.4 2e-06 27.3 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG13003.1 - 1.5e-05 24.6 1.7 2.3e-05 24.0 1.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG13003.1 - 3.5e-05 23.7 3.8 5.9e-05 23.0 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG13003.1 - 0.022 14.4 1.7 0.04 13.5 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG13003.1 - 0.025 14.2 1.2 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 EKG13003.1 - 0.045 13.5 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EKG13003.1 - 0.053 13.6 0.4 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EKG13003.1 - 0.086 12.3 3.0 0.18 11.3 2.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EKG13003.1 - 0.3 10.6 4.2 0.58 9.7 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EKG13003.1 - 0.32 10.8 6.1 3.9 7.4 2.1 3.1 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING DUF2293 PF10056.4 EKG13004.1 - 1.3e-28 98.7 0.4 5.7e-28 96.7 0.3 2.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Complex1_LYR PF05347.10 EKG13005.1 - 4.4e-06 26.4 3.3 4.4e-06 26.4 2.3 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) EHN PF06441.7 EKG13005.1 - 0.012 15.5 1.2 0.012 15.5 0.8 1.6 1 1 1 2 2 2 0 Epoxide hydrolase N terminus Complex1_LYR_1 PF13232.1 EKG13005.1 - 1.5 9.0 7.9 0.3 11.3 2.0 2.1 2 0 0 2 2 2 0 Complex1_LYR-like DUF814 PF05670.8 EKG13006.1 - 1.5e-11 44.0 0.0 2.3e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) UCR_TM PF02921.9 EKG13007.1 - 4.9e-19 68.3 0.5 1.2e-18 67.1 0.3 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EKG13007.1 - 1.3e-16 59.9 0.0 2.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Macro PF01661.16 EKG13008.1 - 2.9e-16 59.4 0.0 4.1e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Macro domain Pmp3 PF01679.12 EKG13009.1 - 1.4e-18 66.2 6.2 1.9e-18 65.9 4.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CM_2 PF01817.16 EKG13010.1 - 1.3e-07 31.5 0.0 0.0036 17.3 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 EKG13011.1 - 9.4e-37 123.5 9.3 2.1e-08 33.6 0.2 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EKG13011.1 - 3.6e-08 32.0 9.3 0.023 12.8 0.2 5.0 2 2 3 5 5 5 4 Nucleoporin Nup120/160 IncA PF04156.9 EKG13011.1 - 0.0012 18.4 6.1 0.0024 17.5 4.3 1.4 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 EKG13011.1 - 0.0022 17.1 4.4 0.0034 16.4 3.1 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 PQQ_2 PF13360.1 EKG13011.1 - 0.0038 16.7 0.2 0.42 10.0 0.0 2.8 2 1 0 3 3 3 1 PQQ-like domain Spc24 PF08286.6 EKG13011.1 - 0.017 14.8 2.1 1.2 8.8 0.2 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Baculo_p24 PF05073.7 EKG13011.1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein IFT57 PF10498.4 EKG13011.1 - 0.035 12.8 2.3 0.073 11.7 1.6 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_23 PF13476.1 EKG13011.1 - 0.05 13.9 2.0 0.07 13.4 1.4 1.2 1 0 0 1 1 1 0 AAA domain Cortex-I_coil PF09304.5 EKG13011.1 - 0.056 13.4 8.3 0.4 10.7 2.4 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil Prefoldin_2 PF01920.15 EKG13011.1 - 2.1 8.1 7.7 2.4 7.9 2.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EKG13011.1 - 4 7.1 8.8 4.8 6.9 2.1 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EKG13011.1 - 8.3 6.2 5.6 51 3.6 2.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RNA_pol PF00940.14 EKG13012.1 - 7.1e-164 545.0 0.0 1.2e-163 544.3 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EKG13012.1 - 1.1e-67 228.5 1.7 2.1e-67 227.6 1.2 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 EKG13012.1 - 0.0098 15.8 0.0 0.041 13.8 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family Rho_GDI PF02115.12 EKG13013.1 - 1e-53 181.7 0.0 1.1e-53 181.6 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP1_TM PF14812.1 EKG13015.1 - 0.036 14.3 1.4 0.04 14.2 1.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Asp-B-Hydro_N PF05279.6 EKG13015.1 - 1.8 8.3 9.0 2.2 8.0 6.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nuf2 PF03800.9 EKG13016.1 - 1e-23 83.9 0.5 1e-23 83.9 0.3 2.2 2 0 0 2 2 2 1 Nuf2 family THUMP PF02926.12 EKG13016.1 - 3.1 7.6 12.2 1.3 8.8 3.6 2.5 2 0 0 2 2 2 0 THUMP domain IncA PF04156.9 EKG13016.1 - 9.1 5.8 58.9 0.93 9.0 12.8 3.1 1 1 2 3 3 3 0 IncA protein Thioredoxin PF00085.15 EKG13018.1 - 1e-28 99.0 0.1 1.2e-28 98.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKG13018.1 - 1.1e-06 28.8 0.6 1.8e-05 24.8 0.4 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EKG13018.1 - 6.7e-06 25.6 0.0 7.6e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKG13018.1 - 2.5e-05 24.3 0.0 0.00037 20.5 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 EKG13018.1 - 0.013 14.9 0.4 0.061 12.8 0.3 1.8 1 1 1 2 2 2 0 Redoxin Phosducin PF02114.11 EKG13018.1 - 0.038 12.6 0.0 0.042 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin AhpC-TSA PF00578.16 EKG13018.1 - 0.054 13.1 0.2 0.073 12.7 0.1 1.4 1 1 0 1 1 1 0 AhpC/TSA family PAN_4 PF14295.1 EKG13019.1 - 3.1e-14 52.4 7.5 4.2e-07 29.5 0.7 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 EKG13019.1 - 1.6e-08 34.2 4.8 0.00011 21.9 2.1 3.4 2 0 0 2 2 2 2 PAN domain ATP-synt_C PF00137.16 EKG13021.1 - 8.1e-15 54.4 12.5 1.1e-14 54.0 8.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit C MFS_3 PF05977.8 EKG13021.1 - 0.039 12.0 3.6 0.044 11.9 2.5 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector ALG3 PF05208.8 EKG13022.1 - 5e-140 466.9 13.9 5.7e-140 466.7 9.6 1.0 1 0 0 1 1 1 1 ALG3 protein EpsG PF14897.1 EKG13022.1 - 0.039 12.8 8.3 0.08 11.8 5.8 1.4 1 1 0 1 1 1 0 EpsG family eIF-1a PF01176.14 EKG13023.1 - 2.7e-13 49.1 0.0 5.2e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF4019 PF13211.1 EKG13023.1 - 0.073 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4019) MFS_1 PF07690.11 EKG13024.1 - 1.8e-15 56.4 19.9 2.2e-15 56.2 13.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1992 PF09350.5 EKG13025.1 - 1.5e-23 82.4 0.5 5.8e-23 80.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Transket_pyr PF02779.19 EKG13026.1 - 5.2e-64 215.0 0.0 1e-63 214.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EKG13026.1 - 6.9e-57 192.4 0.0 9.4e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component RRF PF01765.14 EKG13033.1 - 1e-26 93.3 0.1 1.4e-26 92.9 0.1 1.1 1 0 0 1 1 1 1 Ribosome recycling factor YbjM PF11045.3 EKG13033.1 - 0.031 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae Glycoprotein_B PF00606.13 EKG13034.1 - 2.4 6.0 6.0 2.4 6.0 4.1 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B peroxidase PF00141.18 EKG13035.1 - 1.8e-38 132.3 0.0 2.4e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Fungal_trans PF04082.13 EKG13036.1 - 1e-20 73.7 0.0 2.5e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EKG13037.1 - 4.4e-29 101.9 6.0 8.4e-29 101.0 4.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13037.1 - 1.3e-09 37.9 0.2 1.8e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG13037.1 - 1.6e-09 37.6 0.1 2.4e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold EHN PF06441.7 EKG13037.1 - 0.12 12.3 0.7 0.21 11.5 0.5 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF1399 PF07173.7 EKG13038.1 - 2.4e-21 76.4 1.4 7.6e-16 58.6 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1399) ABC2_membrane PF01061.19 EKG13039.1 - 1.1e-95 318.7 60.3 3.8e-49 166.7 14.4 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EKG13039.1 - 2.4e-39 133.1 0.5 8.3e-34 115.3 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EKG13039.1 - 1.1e-38 132.6 0.6 4e-18 66.0 0.0 3.3 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.1 EKG13039.1 - 5.4e-23 80.8 0.0 2.1e-22 78.9 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EKG13039.1 - 2.2e-08 33.7 0.0 1.8e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EKG13039.1 - 9.4e-07 28.8 1.1 0.0037 17.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EKG13039.1 - 4.6e-06 26.7 0.2 0.0012 18.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EKG13039.1 - 7.9e-06 25.1 0.0 0.0018 17.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EKG13039.1 - 2.3e-05 23.7 0.0 0.16 11.1 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 EKG13039.1 - 6.3e-05 22.4 0.7 0.0088 15.5 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EKG13039.1 - 0.0001 21.7 1.5 0.024 14.1 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EKG13039.1 - 0.0019 18.9 0.0 0.61 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG13039.1 - 0.0019 18.4 0.1 0.64 10.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EKG13039.1 - 0.0035 17.4 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG13039.1 - 0.0067 16.1 1.8 3.2 7.5 0.1 2.5 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 EKG13039.1 - 0.0073 15.9 0.1 1.3 8.6 0.1 2.7 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EKG13039.1 - 0.0082 16.3 0.0 3.1 7.9 0.0 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKG13039.1 - 0.019 14.6 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_21 PF13304.1 EKG13039.1 - 0.026 14.4 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EKG13039.1 - 0.041 13.8 0.3 2.3 8.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EKG13039.1 - 0.073 12.4 0.5 3.2 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EKG13039.1 - 0.12 12.3 0.0 64 3.5 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase WD40 PF00400.27 EKG13040.1 - 1e-38 129.8 22.4 4.4e-08 32.7 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EKG13040.1 - 4.5e-11 42.2 0.2 9.3e-11 41.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EKG13040.1 - 2e-07 29.5 1.1 0.0072 14.5 0.0 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.28 EKG13040.1 - 7.1e-05 22.3 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain FlaG PF03646.10 EKG13040.1 - 10 6.3 11.5 6.8 6.8 0.0 3.1 3 0 0 3 3 3 0 FlaG protein Med15 PF09606.5 EKG13040.1 - 10 4.2 33.0 21 3.1 22.9 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PH_10 PF15411.1 EKG13041.1 - 8.3e-44 148.4 0.1 1.8e-43 147.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EKG13041.1 - 3.4e-35 119.9 0.4 1.8e-34 117.6 0.0 2.1 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.15 EKG13041.1 - 1.8e-32 112.6 1.0 3.5e-32 111.7 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EKG13041.1 - 3.1e-10 39.5 0.2 9.4e-10 38.0 0.1 1.9 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EKG13041.1 - 0.037 14.2 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 PH domain Periviscerokin PF08259.6 EKG13041.1 - 2.8 8.2 6.1 0.33 11.1 0.8 2.2 2 0 0 2 2 2 0 Periviscerokinin family Shisa PF13908.1 EKG13043.1 - 7.8e-05 22.9 2.2 0.0002 21.6 1.5 1.8 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EKG13043.1 - 0.00035 18.9 7.3 0.0017 16.6 5.1 1.9 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 EKG13043.1 - 0.0049 16.2 0.6 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF1191 PF06697.7 EKG13043.1 - 0.019 13.7 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Syndecan PF01034.15 EKG13043.1 - 0.17 11.5 1.1 0.34 10.5 0.8 1.4 1 0 0 1 1 1 0 Syndecan domain PmbA_TldD PF01523.11 EKG13046.1 - 0.065 12.5 0.6 0.15 11.3 0.4 1.5 1 0 0 1 1 1 0 Putative modulator of DNA gyrase U1snRNP70_N PF12220.3 EKG13046.1 - 0.48 10.7 6.4 23 5.4 0.0 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Methyltransf_6 PF03737.10 EKG13047.1 - 3.5e-16 59.4 0.2 7.3e-16 58.4 0.2 1.6 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase MFS_1 PF07690.11 EKG13048.1 - 1.1e-31 109.8 28.6 1.2e-31 109.6 19.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EKG13048.1 - 0.0036 17.0 0.1 0.011 15.5 0.1 1.8 1 0 0 1 1 1 1 MFS_1 like family Myb_DNA-bind_6 PF13921.1 EKG13049.1 - 5.2e-06 26.4 0.1 0.00014 21.8 0.3 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG13049.1 - 0.0018 18.2 0.8 0.029 14.4 0.9 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG13050.1 - 2.2e-05 24.4 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EKG13050.1 - 0.026 14.3 0.1 0.039 13.7 0.0 1.3 1 1 0 1 1 1 0 Rap1 Myb domain DUF2849 PF11011.3 EKG13050.1 - 0.097 12.9 0.2 0.11 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2849) Myb_DNA-bind_6 PF13921.1 EKG13051.1 - 6.8e-15 54.9 0.0 6.6e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG13051.1 - 1.2e-09 38.0 0.0 6.1e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 EKG13051.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_32 PF13565.1 EKG13051.1 - 0.13 13.1 0.2 1.4 9.7 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain HMG-CoA_red PF00368.13 EKG13052.1 - 1.8e-157 523.7 5.5 2.5e-157 523.3 3.8 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EKG13052.1 - 6.8e-46 155.7 0.2 1.2e-45 154.8 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EKG13052.1 - 1.8e-16 59.9 2.4 4.6e-16 58.6 1.6 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EKG13052.1 - 2.3e-07 29.1 1.6 2.3e-07 29.1 1.1 1.6 2 0 0 2 2 2 1 Patched family DUF3605 PF12239.3 EKG13053.1 - 5.6e-16 58.7 0.0 7.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF2407_C PF13373.1 EKG13054.1 - 0.13 12.1 0.1 0.21 11.5 0.1 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain DUF3285 PF11688.3 EKG13054.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) zf-CCCH PF00642.19 EKG13056.1 - 7.3e-09 35.1 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EKG13056.1 - 0.00018 21.3 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG13056.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG13056.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-SAP30 PF13866.1 EKG13056.1 - 0.096 12.3 0.7 1 9.0 0.1 2.2 2 0 0 2 2 2 0 SAP30 zinc-finger Peptidase_S28 PF05577.7 EKG13057.1 - 6.5e-51 173.2 4.7 6e-50 170.0 3.2 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 EKG13057.1 - 0.027 12.9 0.1 0.043 12.2 0.0 1.3 1 0 0 1 1 1 0 PS-10 peptidase S37 Cu-oxidase_3 PF07732.10 EKG13058.1 - 9e-42 141.5 2.0 6.5e-41 138.7 1.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG13058.1 - 1.4e-38 131.5 5.0 2.5e-35 120.9 0.1 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EKG13058.1 - 6.9e-36 123.5 0.0 1.6e-35 122.3 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Lactamase_B PF00753.22 EKG13060.1 - 1.7e-09 37.6 4.4 8.4e-09 35.3 3.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG13060.1 - 0.00071 19.1 0.1 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain His_Phos_1 PF00300.17 EKG13061.1 - 6.9e-30 104.2 0.0 8.3e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Oxysterol_BP PF01237.13 EKG13062.1 - 2.5e-91 305.8 0.0 3.1e-91 305.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein SNF2_N PF00176.18 EKG13063.1 - 2.9e-54 183.9 0.1 4.9e-54 183.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EKG13063.1 - 3.2e-23 81.4 0.6 8.9e-23 79.9 0.4 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EKG13063.1 - 2.4e-14 52.9 0.0 9e-14 51.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG13063.1 - 4.4e-06 26.6 0.0 6.7e-05 22.7 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit YlbD_coat PF14071.1 EKG13063.1 - 0.031 14.3 0.4 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 Putative coat protein Myb_DNA-bind_6 PF13921.1 EKG13065.1 - 0.00094 19.2 0.7 0.31 11.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 EKG13065.1 - 0.0046 16.3 1.2 0.0056 16.1 0.0 1.7 2 0 0 2 2 2 1 Sigma-70, region 4 Myb_DNA-bind_3 PF12776.2 EKG13065.1 - 0.027 15.0 0.9 0.24 12.0 0.1 2.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG13065.1 - 0.05 13.6 0.1 0.8 9.8 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKG13065.1 - 0.34 10.8 3.3 2.7 7.9 0.2 2.3 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 EKG13066.1 - 6.8e-26 90.8 35.4 1.1e-23 83.5 7.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG13066.1 - 9.6e-05 21.1 0.5 9.6e-05 21.1 0.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EKG13066.1 - 0.02 12.9 0.2 0.034 12.2 0.1 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family S10_plectin PF03501.10 EKG13066.1 - 0.042 13.7 0.3 0.073 12.9 0.2 1.3 1 0 0 1 1 1 0 Plectin/S10 domain Inositol_P PF00459.20 EKG13068.1 - 9.3e-56 189.1 0.0 1.1e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Methyltransf_23 PF13489.1 EKG13069.1 - 5.6e-20 71.6 0.1 7.9e-20 71.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG13069.1 - 3.9e-11 43.2 0.0 1.1e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13069.1 - 2.7e-10 40.0 0.0 1.4e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13069.1 - 3e-10 40.6 0.2 3.2e-09 37.3 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13069.1 - 3.7e-08 33.7 0.0 7.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG13069.1 - 8.9e-06 26.0 0.0 2.2e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG13069.1 - 1.3e-05 24.3 0.0 0.00033 19.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EKG13069.1 - 0.002 17.5 0.0 0.0058 16.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EKG13069.1 - 0.0077 15.7 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EKG13069.1 - 0.015 14.3 0.0 0.12 11.5 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EKG13069.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EKG13069.1 - 0.063 13.3 0.1 0.18 11.8 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EKG13069.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF554 PF04474.7 EKG13070.1 - 0.029 13.5 0.2 0.065 12.3 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF554) Claudin_2 PF13903.1 EKG13070.1 - 0.21 11.2 4.5 0.072 12.7 1.1 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 EKG13070.1 - 0.21 11.6 7.0 1.7 8.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Pkinase PF00069.20 EKG13073.1 - 1.4e-13 50.5 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG13073.1 - 1e-07 31.3 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_3 PF13920.1 EKG13075.1 - 2.1e-07 30.4 10.2 3.7e-07 29.6 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.19 EKG13076.1 - 2.5e-76 257.0 17.0 4.3e-76 256.2 11.7 1.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG13076.1 - 3.2e-14 52.4 28.9 4.3e-14 52.0 20.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_S21e PF01249.13 EKG13078.1 - 9.1e-42 140.9 0.0 1e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Abhydrolase_6 PF12697.2 EKG13079.1 - 1.1e-25 90.8 0.2 2e-25 90.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13079.1 - 6e-15 55.2 0.0 1.8e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG13079.1 - 1.3e-10 41.2 0.0 2.7e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 EKG13079.1 - 7.5e-10 38.5 0.0 3.6e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 EKG13079.1 - 0.0016 18.7 0.2 0.0029 17.8 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.1 EKG13079.1 - 0.0031 17.5 0.0 0.0057 16.7 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Ser_hydrolase PF06821.8 EKG13079.1 - 0.0071 15.9 0.1 0.39 10.3 0.0 2.6 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.5 EKG13079.1 - 0.0073 16.1 0.0 0.021 14.7 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Hydrolase_4 PF12146.3 EKG13079.1 - 0.0092 15.8 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Y_phosphatase PF00102.22 EKG13079.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF676 PF05057.9 EKG13079.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.10 EKG13079.1 - 0.039 12.9 0.0 0.06 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 EKG13079.1 - 0.058 12.7 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ILVD_EDD PF00920.16 EKG13080.1 - 7.8e-201 668.0 2.6 8.9e-201 667.8 1.8 1.0 1 0 0 1 1 1 1 Dehydratase family DUF2148 PF09918.4 EKG13080.1 - 0.091 12.4 0.0 0.81 9.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) NUDIX PF00293.23 EKG13081.1 - 3.6e-11 42.8 0.0 1.6e-07 31.0 0.0 2.9 2 1 0 2 2 2 2 NUDIX domain ABC_membrane PF00664.18 EKG13082.1 - 7.5e-71 238.7 25.6 3.6e-38 131.5 4.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EKG13082.1 - 6.3e-66 220.8 0.0 1.2e-33 116.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKG13082.1 - 2.4e-16 59.6 0.2 8.8e-07 28.3 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG13082.1 - 1.3e-14 54.8 0.4 0.0064 16.4 0.0 5.1 5 0 0 5 5 5 4 AAA domain AAA_29 PF13555.1 EKG13082.1 - 6.9e-10 38.3 1.1 0.0012 18.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EKG13082.1 - 1.2e-09 37.2 0.2 0.0041 15.7 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.1 EKG13082.1 - 3.6e-08 33.6 0.6 0.12 12.5 0.2 4.2 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EKG13082.1 - 1.1e-07 32.6 0.0 0.034 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EKG13082.1 - 1.2e-06 27.7 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG13082.1 - 1.7e-06 28.1 3.5 0.0058 16.6 0.1 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.1 EKG13082.1 - 2.6e-05 24.6 0.5 0.52 10.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EKG13082.1 - 3.8e-05 23.9 0.0 0.29 11.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EKG13082.1 - 4.8e-05 23.0 0.0 0.036 13.6 0.0 3.6 3 1 0 3 3 3 1 AAA domain DUF87 PF01935.12 EKG13082.1 - 0.00026 20.9 0.3 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_19 PF13245.1 EKG13082.1 - 0.0003 20.4 1.0 0.59 9.9 0.0 3.6 3 1 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 EKG13082.1 - 0.00036 19.9 0.1 0.77 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EKG13082.1 - 0.00095 19.0 0.4 0.58 10.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EKG13082.1 - 0.0016 17.5 0.0 0.59 9.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EKG13082.1 - 0.0021 17.5 0.8 1.3 8.3 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain APS_kinase PF01583.15 EKG13082.1 - 0.0031 17.1 0.1 2.6 7.6 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.1 EKG13082.1 - 0.0054 16.6 2.0 0.78 9.6 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 EKG13082.1 - 0.0062 15.2 0.4 0.35 9.4 0.0 2.5 2 1 0 3 3 3 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 EKG13082.1 - 0.0095 15.6 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EKG13082.1 - 0.02 14.8 0.4 4.7 7.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EKG13082.1 - 0.022 14.4 0.4 9.6 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EKG13082.1 - 0.028 14.3 0.0 7.9 6.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF3987 PF13148.1 EKG13082.1 - 0.034 12.7 0.1 2.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PRK PF00485.13 EKG13082.1 - 0.045 13.2 0.2 9.8 5.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.1 EKG13082.1 - 0.067 12.7 0.0 3.8 7.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EKG13082.1 - 0.12 11.9 0.2 12 5.5 0.0 3.0 3 0 0 3 3 3 0 NACHT domain DEAD PF00270.24 EKG13082.1 - 0.12 11.8 0.0 3.7 7.0 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase G-alpha PF00503.15 EKG13082.1 - 0.15 10.7 0.0 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.17 EKG13082.1 - 0.17 12.0 0.1 24 5.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EKG13082.1 - 0.25 10.3 0.0 22 3.9 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain EBV-NA3 PF05009.7 EKG13082.1 - 0.62 9.2 1.0 1.2 8.3 0.7 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) MFS_1 PF07690.11 EKG13083.1 - 1.4e-16 60.1 23.5 1.9e-16 59.7 16.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG13083.1 - 1.2e-06 27.0 8.8 1.6e-06 26.6 6.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG13083.1 - 0.0041 15.7 10.1 0.009 14.6 7.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter PGPGW PF09656.5 EKG13083.1 - 0.076 12.3 0.6 0.33 10.2 0.4 2.1 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) Pyr_redox PF00070.22 EKG13084.1 - 8.5e-11 42.1 0.1 1.6e-10 41.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG13084.1 - 4.9e-08 33.0 0.0 0.0031 17.4 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG13084.1 - 8.8e-07 29.1 0.0 3.8e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG13084.1 - 0.00037 19.5 0.0 0.053 12.4 0.0 2.1 1 1 1 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.1 EKG13084.1 - 0.00041 19.3 0.0 0.00059 18.8 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EKG13084.1 - 0.069 12.0 0.2 5.2 5.8 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase KR PF08659.5 EKG13084.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 KR domain Acetyltransf_8 PF13523.1 EKG13085.1 - 1.8e-40 138.2 1.0 2.7e-40 137.7 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG13085.1 - 0.062 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 EKG13086.1 - 1.4e-62 211.4 0.0 1.7e-62 211.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 EKG13087.1 - 8.7e-224 742.4 0.0 3.3e-74 249.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EKG13087.1 - 5.5e-160 531.1 1.4 1.7e-36 125.5 0.4 5.3 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 EKG13087.1 - 1.1e-48 163.3 4.7 3.4e-09 36.8 0.0 6.9 7 0 0 7 7 7 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG13087.1 - 7.1e-20 71.7 1.5 3.6e-07 31.0 0.0 4.2 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EKG13087.1 - 0.00011 20.7 2.5 0.003 16.0 0.1 3.1 3 0 0 3 3 3 1 Transferase family AATase PF07247.7 EKG13087.1 - 0.1 11.1 0.1 57 2.0 0.0 3.6 4 0 0 4 4 4 0 Alcohol acetyltransferase Bac_rhamnosid PF05592.6 EKG13088.1 - 2.2e-25 88.8 1.6 3.2e-23 81.7 0.3 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EKG13088.1 - 9.9e-06 24.4 0.7 1.5e-05 23.8 0.5 1.2 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 EKG13088.1 - 0.00011 21.0 3.2 0.00018 20.3 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Chorion_2 PF03964.10 EKG13089.1 - 0.6 10.6 6.2 0.38 11.3 2.1 2.0 1 1 1 2 2 2 0 Chorion family 2 Tyrosinase PF00264.15 EKG13090.1 - 9.1e-12 45.6 0.0 1.1e-11 45.3 0.0 1.0 1 0 0 1 1 1 1 Common central domain of tyrosinase Bax1-I PF01027.15 EKG13091.1 - 6.3e-31 107.5 7.2 8.9e-31 107.0 5.0 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 EKG13091.1 - 0.13 12.3 4.1 7.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) RasGAP_C PF03836.10 EKG13092.1 - 1.2e-49 167.6 3.5 4.7e-49 165.7 2.4 2.2 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EKG13092.1 - 7.7e-41 139.9 0.0 1.9e-40 138.6 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EKG13092.1 - 7.1e-20 68.6 51.1 0.00024 20.4 0.3 17.5 18 0 0 18 18 18 9 IQ calmodulin-binding motif CH PF00307.26 EKG13092.1 - 3.6e-11 43.0 0.0 1.1e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IMPDH PF00478.20 EKG13093.1 - 2.4e-130 434.5 1.2 3.4e-130 434.0 0.9 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EKG13093.1 - 1.1e-17 63.4 0.1 3.9e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EKG13093.1 - 3.2e-06 26.2 0.8 1.1e-05 24.4 0.2 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EKG13093.1 - 7.4e-06 25.3 6.1 0.0063 15.7 2.9 2.4 3 0 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EKG13093.1 - 0.0018 17.5 1.5 0.0067 15.7 1.1 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 EKG13093.1 - 0.013 14.4 0.2 0.023 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 EKG13093.1 - 0.046 12.7 1.8 0.053 12.5 0.2 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 EKG13093.1 - 0.18 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Acyl-CoA_dh_N PF02771.11 EKG13094.1 - 1.6e-06 28.6 0.0 2.4e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EKG13094.1 - 0.0001 21.7 0.2 0.00019 20.8 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Glucosaminidase PF01832.15 EKG13094.1 - 0.17 12.0 0.0 0.22 11.6 0.0 1.1 1 0 0 1 1 1 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase CoA_transf_3 PF02515.12 EKG13095.1 - 2.8e-57 193.0 0.0 3.3e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III COX5B PF01215.14 EKG13096.1 - 2.1e-13 50.1 0.2 2.6e-10 40.0 0.1 2.1 1 1 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EKG13096.1 - 0.0034 16.8 0.8 1.7 8.2 0.1 3.1 3 0 0 3 3 3 2 Topoisomerase DNA binding C4 zinc finger Ogr_Delta PF04606.7 EKG13096.1 - 0.53 9.9 2.2 8.7 6.0 0.2 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger CGI-121 PF08617.5 EKG13097.1 - 5.8e-51 172.3 0.4 8.2e-51 171.8 0.3 1.2 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.13 EKG13098.1 - 4.6e-17 61.7 0.3 7.6e-17 61.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG13098.1 - 2.1e-07 30.7 9.9 2.1e-07 30.7 6.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hyd_65N_2 PF14498.1 EKG13099.1 - 3.7e-36 125.0 0.0 6.1e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.10 EKG13099.1 - 0.00075 18.2 0.1 0.0013 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Aldedh PF00171.17 EKG13100.1 - 1.1e-134 449.2 0.1 1.3e-134 449.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EKG13100.1 - 3.6e-06 25.9 0.0 6.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Glyco_hydro_47 PF01532.15 EKG13101.1 - 2e-129 432.2 0.0 2.4e-129 431.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NIF PF03031.13 EKG13102.1 - 1.2e-39 135.4 0.0 1.8e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TENA_THI-4 PF03070.11 EKG13103.1 - 5.5e-08 32.8 0.0 7.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Nodulin PF02451.10 EKG13103.1 - 0.17 11.3 1.2 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 Nodulin GPI-anchored PF10342.4 EKG13104.1 - 2e-17 63.4 2.3 1.3e-16 60.8 0.1 2.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fungal_trans PF04082.13 EKG13105.1 - 9.4e-18 64.0 0.0 2e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG13105.1 - 3.9e-09 36.2 12.8 7.5e-09 35.3 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_B561 PF03188.11 EKG13106.1 - 1.1e-06 28.5 9.0 1.2e-06 28.3 5.0 2.1 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EKG13106.1 - 5.3e-06 25.9 2.7 1.8e-05 24.2 0.5 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) DOMON PF03351.12 EKG13106.1 - 0.00082 19.3 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Bax1-I PF01027.15 EKG13106.1 - 0.00086 18.9 0.9 0.0014 18.2 0.7 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Cytochrom_B_N PF00033.14 EKG13106.1 - 0.00088 18.6 8.2 0.062 12.6 5.7 2.6 1 1 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB DUF2306 PF10067.4 EKG13106.1 - 0.0017 18.4 4.2 0.0058 16.7 0.2 2.5 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) XK-related PF09815.4 EKG13106.1 - 0.0028 16.7 0.3 0.0049 15.9 0.2 1.3 1 0 0 1 1 1 1 XK-related protein Ni_hydr_CYTB PF01292.15 EKG13106.1 - 0.0033 16.8 5.7 0.0071 15.7 4.0 1.5 1 1 0 1 1 1 1 Prokaryotic cytochrome b561 TauE PF01925.14 EKG13106.1 - 0.027 13.9 10.9 0.019 14.4 5.2 2.1 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE DUF998 PF06197.8 EKG13106.1 - 0.05 12.9 15.9 0.44 9.8 2.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF2207 PF09972.4 EKG13106.1 - 0.083 11.4 0.2 0.44 9.0 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2157 PF09925.4 EKG13106.1 - 0.094 12.3 7.8 1.2 8.7 0.3 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) RseC_MucC PF04246.7 EKG13106.1 - 0.097 12.2 2.9 3 7.3 0.1 2.9 2 1 1 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.1 EKG13106.1 - 4 6.8 11.7 23 4.3 2.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) SdpI PF13630.1 EKG13106.1 - 7.9 6.2 9.7 1.5 8.6 0.6 2.7 2 1 0 2 2 2 0 SdpI/YhfL protein family ERG4_ERG24 PF01222.12 EKG13107.1 - 6.8e-87 291.7 15.8 8.2e-87 291.5 11.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EKG13107.1 - 0.00039 19.7 0.1 0.00039 19.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) DUF1218 PF06749.7 EKG13108.1 - 0.039 14.3 4.4 0.055 13.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DUF3275 PF11679.3 EKG13108.1 - 9.1 5.8 6.3 16 5.0 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) p450 PF00067.17 EKG13109.1 - 5.3e-35 120.8 0.0 6.1e-35 120.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BRF1 PF07741.8 EKG13109.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4075 PF13294.1 EKG13109.1 - 0.089 12.8 0.0 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4075) SAPS PF04499.10 EKG13110.1 - 7.7e-194 644.7 7.4 1.1e-193 644.2 4.0 2.1 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Snf7 PF03357.16 EKG13111.1 - 2.7e-45 153.8 16.3 3.2e-45 153.5 11.3 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EKG13111.1 - 0.0011 18.4 12.4 0.0025 17.2 7.8 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EKG13111.1 - 0.0083 15.3 3.7 0.02 14.0 0.8 2.0 1 1 1 2 2 2 1 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EKG13111.1 - 0.012 15.8 8.1 0.24 11.6 0.8 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.4 EKG13111.1 - 0.13 11.1 11.3 0.19 10.6 7.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 EKG13111.1 - 0.2 10.9 3.6 1.2 8.3 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 EKG13111.1 - 0.21 9.9 12.4 0.45 8.8 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CDC37_N PF03234.9 EKG13111.1 - 0.31 11.3 9.7 0.41 10.9 6.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Baculo_PEP_C PF04513.7 EKG13111.1 - 0.35 10.6 4.7 6.7 6.5 0.0 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CompInhib_SCIN PF11546.3 EKG13111.1 - 0.53 10.1 4.9 0.3 10.9 0.3 2.3 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN DUF4140 PF13600.1 EKG13111.1 - 0.9 10.0 0.0 0.9 10.0 0.0 3.3 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 EKG13111.1 - 1.6 8.6 19.1 0.77 9.6 9.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.7 EKG13111.1 - 1.8 8.3 9.9 0.81 9.4 1.1 2.3 1 1 1 2 2 2 0 Laminin Domain II Mod_r PF07200.8 EKG13111.1 - 1.8 8.4 12.8 0.6 10.0 5.1 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1090 PF06476.7 EKG13111.1 - 2 8.1 9.2 9.8 5.8 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) GrpE PF01025.14 EKG13111.1 - 2.2 7.8 12.9 0.66 9.4 5.4 2.2 1 1 0 2 2 2 0 GrpE DUF4337 PF14235.1 EKG13111.1 - 2.4 7.9 10.0 0.32 10.8 3.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Uds1 PF15456.1 EKG13111.1 - 2.5 8.1 9.1 1.6 8.6 3.1 2.1 1 1 1 2 2 2 0 Up-regulated During Septation FliJ PF02050.11 EKG13111.1 - 3.3 7.7 15.6 4.3 7.4 6.9 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein EMP24_GP25L PF01105.19 EKG13111.1 - 3.4 7.3 5.9 13 5.4 0.0 2.5 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD IncA PF04156.9 EKG13111.1 - 3.9 7.0 9.6 8.5 5.9 3.9 2.3 1 1 1 2 2 2 0 IncA protein Cortex-I_coil PF09304.5 EKG13111.1 - 5.5 7.0 12.6 4.9 7.2 6.3 2.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil COG2 PF06148.6 EKG13111.1 - 6 6.7 8.1 15 5.4 2.7 2.7 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 E1-E2_ATPase PF00122.15 EKG13112.1 - 6.9e-65 218.2 1.7 1.2e-64 217.5 1.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG13112.1 - 1.7e-34 118.9 3.4 1.7e-34 118.9 2.4 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG13112.1 - 1.3e-26 94.4 0.0 2.6e-25 90.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG13112.1 - 3.3e-22 78.2 0.0 1.1e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EKG13112.1 - 1.6e-16 59.5 0.2 1.5e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EKG13112.1 - 7.2e-11 42.6 0.1 3.6e-10 40.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG13112.1 - 0.00035 20.2 0.5 0.02 14.4 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Methyltransf_23 PF13489.1 EKG13114.1 - 3.9e-20 72.1 0.0 7.5e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13114.1 - 6e-09 36.4 0.0 4.8e-08 33.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13114.1 - 1.1e-07 31.6 0.0 3.1e-06 26.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13114.1 - 1.3e-07 32.0 0.0 7.1e-07 29.6 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Stn1 PF10451.4 EKG13114.1 - 1.3e-07 30.7 0.3 2.5e-06 26.5 0.2 2.1 1 1 0 1 1 1 1 Telomere regulation protein Stn1 Methyltransf_12 PF08242.7 EKG13114.1 - 1.9e-06 28.2 0.0 3.4e-05 24.2 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG13114.1 - 3.8e-05 23.9 0.0 0.0022 18.3 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG13114.1 - 0.014 14.4 0.8 0.032 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 EKG13114.1 - 0.015 14.4 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EKG13114.1 - 0.016 15.2 0.0 0.044 13.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF2514 PF10721.4 EKG13114.1 - 0.091 12.4 4.6 0.18 11.5 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) GidB PF02527.10 EKG13114.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DDE_Tnp_4 PF13359.1 EKG13115.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease dCMP_cyt_deam_1 PF00383.17 EKG13116.1 - 2e-17 62.6 0.1 3.3e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Herpes_U47 PF05467.6 EKG13116.1 - 0.1 10.4 0.0 0.13 10.1 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 NADH-G_4Fe-4S_3 PF10588.4 EKG13116.1 - 0.16 11.2 0.8 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DnaJ PF00226.26 EKG13117.1 - 1.9e-23 81.9 6.3 2.8e-23 81.4 0.8 3.0 3 0 0 3 3 3 1 DnaJ domain RPT PF13446.1 EKG13117.1 - 0.09 12.1 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF1843 PF08898.5 EKG13117.1 - 0.14 12.1 6.5 1.8 8.6 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) Hexapep PF00132.19 EKG13120.1 - 9.2e-08 31.2 16.4 0.055 12.9 0.5 5.4 3 2 3 6 6 6 6 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKG13120.1 - 0.19 11.2 14.7 0.64 9.6 0.7 3.7 2 2 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase HORMA PF02301.13 EKG13121.1 - 2.1e-23 82.8 0.0 6.3e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 HORMA domain PHD PF00628.24 EKG13121.1 - 3e-05 23.6 12.8 5.7e-05 22.7 8.9 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EKG13121.1 - 0.078 12.3 5.7 0.15 11.3 4.0 1.5 1 0 0 1 1 1 0 PHD-finger WD40 PF00400.27 EKG13122.1 - 1.6e-56 186.3 18.9 7e-11 41.5 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EKG13122.1 - 6.8e-10 38.5 0.1 1.3e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG13122.1 - 4.2e-09 35.8 0.1 9.3e-09 34.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EKG13122.1 - 2e-05 22.9 8.1 0.21 9.6 0.1 4.9 2 2 1 5 5 5 4 Nucleoporin Nup120/160 NAD_binding_4 PF07993.7 EKG13123.1 - 1.8e-28 99.1 0.0 2.8e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EKG13123.1 - 2.4e-25 88.8 0.0 2.4e-24 85.5 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EKG13123.1 - 3.9e-09 36.6 0.0 8.6e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EKG13123.1 - 5e-07 29.3 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EKG13123.1 - 7.8e-06 25.8 0.0 2.9e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13123.1 - 0.00028 20.5 0.2 0.002 17.8 0.1 2.4 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EKG13123.1 - 0.00039 19.2 0.0 0.002 16.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EKG13123.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EKG13123.1 - 0.19 12.0 0.0 0.73 10.1 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Transp_cyt_pur PF02133.10 EKG13124.1 - 6.8e-88 295.1 31.0 7.7e-88 294.9 21.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4448 PF14610.1 EKG13124.1 - 0.057 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Fungal_trans PF04082.13 EKG13125.1 - 6.3e-23 80.9 3.2 9.7e-23 80.3 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG13125.1 - 8.7e-05 22.3 6.3 0.00015 21.5 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.21 EKG13126.1 - 5.1e-21 74.4 0.0 3.1e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG13126.1 - 1.3e-18 67.0 0.0 2.6e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EKG13126.1 - 6.2e-12 45.3 0.1 3e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EKG13126.1 - 1.8e-05 24.8 0.0 0.00015 21.8 0.0 2.4 2 0 0 2 2 2 1 GAF domain Amidohydro_4 PF13147.1 EKG13127.1 - 3.9e-25 89.4 0.0 5.3e-24 85.7 0.0 2.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG13127.1 - 2e-17 63.8 0.1 9.7e-16 58.3 0.1 2.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKG13127.1 - 2.2e-12 46.6 0.3 8.9e-12 44.6 0.2 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG13127.1 - 3.2e-11 43.1 0.1 1.1e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 EKG13127.1 - 0.13 12.3 0.4 0.38 10.9 0.2 1.8 1 1 1 2 2 2 0 Urease alpha-subunit, N-terminal domain Asp_Glu_race PF01177.17 EKG13128.1 - 4.6e-29 101.8 1.1 7.9e-29 101.1 0.8 1.4 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase CN_hydrolase PF00795.17 EKG13128.1 - 1.9e-16 59.9 0.0 4.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BRAP2 PF07576.7 EKG13130.1 - 2.9e-26 91.1 0.0 5.4e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EKG13130.1 - 4.1e-20 71.6 5.3 9.6e-20 70.4 3.6 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EKG13130.1 - 2.3e-09 36.8 9.6 2.3e-09 36.8 6.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EKG13130.1 - 2e-05 24.1 7.3 5.3e-05 22.7 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG13130.1 - 0.00024 20.7 6.5 0.00024 20.7 4.5 2.4 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG13130.1 - 0.00043 19.8 5.6 0.00043 19.8 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG13130.1 - 0.00088 19.3 4.3 0.00088 19.3 3.0 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKG13130.1 - 0.001 19.0 8.6 0.001 19.0 5.9 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG13130.1 - 0.0054 16.4 6.0 0.0059 16.2 1.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EKG13130.1 - 0.0081 15.9 4.1 0.024 14.4 2.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DivIC PF04977.10 EKG13130.1 - 0.0085 15.5 10.4 0.5 9.8 2.2 2.4 2 0 0 2 2 2 2 Septum formation initiator zf-RING_6 PF14835.1 EKG13130.1 - 0.016 14.9 3.6 0.016 14.9 2.5 2.2 3 0 0 3 3 2 0 zf-RING of BARD1-type protein Filament PF00038.16 EKG13130.1 - 0.019 14.4 11.9 0.029 13.8 8.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein CALCOCO1 PF07888.6 EKG13130.1 - 0.023 13.0 11.5 0.043 12.1 8.0 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-Q PF13094.1 EKG13130.1 - 0.031 14.2 13.0 0.066 13.2 9.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4320 PF14208.1 EKG13130.1 - 0.12 12.2 0.3 0.25 11.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF812 PF05667.6 EKG13130.1 - 0.27 9.7 11.5 0.41 9.0 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CCDC155 PF14662.1 EKG13130.1 - 0.28 10.7 17.8 0.43 10.1 12.3 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Nsp1_C PF05064.8 EKG13130.1 - 0.83 9.3 8.9 6.5 6.4 0.5 2.6 2 1 0 2 2 2 0 Nsp1-like C-terminal region TMF_DNA_bd PF12329.3 EKG13130.1 - 1.1 9.1 17.7 3.3 7.6 1.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TerY-C PF15616.1 EKG13130.1 - 2 8.3 14.5 3.9 7.4 3.0 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain GAS PF13851.1 EKG13130.1 - 2.4 7.3 16.3 0.46 9.6 2.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 EKG13130.1 - 2.8 8.0 5.6 1.5 8.9 0.5 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 EKG13130.1 - 3.4 8.0 11.2 2.5 8.5 2.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EKG13130.1 - 4.4 7.6 18.3 1.6 9.0 1.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF904) ADIP PF11559.3 EKG13130.1 - 4.4 7.1 16.4 2.1e+02 1.7 0.0 3.1 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EKG13130.1 - 5.5 4.7 8.4 7.8 4.2 5.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 EKG13130.1 - 6.8 6.6 19.6 0.22 11.4 4.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.1 EKG13130.1 - 9.2 4.5 13.0 30 2.8 9.1 1.6 1 1 0 1 1 1 0 AAA domain Mannosyl_trans2 PF04188.8 EKG13131.1 - 3.9e-61 207.3 12.3 4.5e-61 207.1 8.5 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) FLILHELTA PF10306.4 EKG13131.1 - 0.042 13.8 0.6 0.12 12.4 0.4 1.7 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA Cyclin_N PF00134.18 EKG13133.1 - 5.7e-12 45.3 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EKG13133.1 - 3.4e-11 43.7 0.0 1.7e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Cyclin Acetyltransf_1 PF00583.19 EKG13134.1 - 4.4e-13 49.0 0.3 6.1e-10 39.0 0.1 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG13134.1 - 3.2e-06 27.2 0.0 4.3e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG13134.1 - 3.4e-05 23.9 0.0 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG13134.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Drf_GBD PF06371.8 EKG13135.1 - 1e-15 57.6 1.0 2.2e-14 53.2 0.7 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain GET2 PF08690.5 EKG13135.1 - 0.2 10.8 2.6 0.39 9.9 1.8 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 ATP_bind_3 PF01171.15 EKG13136.1 - 4.3e-15 55.6 0.0 7.5e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EKG13136.1 - 0.0091 16.3 0.1 0.024 14.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EKG13136.1 - 0.023 14.1 1.4 0.023 14.1 0.9 3.3 5 0 0 5 5 5 0 RecR protein tRNA_Me_trans PF03054.11 EKG13136.1 - 0.049 12.1 0.1 0.083 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA methyl transferase LRR_6 PF13516.1 EKG13138.1 - 1.6e-06 27.5 2.5 0.24 11.6 0.1 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 EKG13138.1 - 1.8e-06 27.1 0.7 0.41 10.8 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.2 EKG13138.1 - 7.8e-06 25.3 0.0 0.19 11.4 0.0 2.8 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG13138.1 - 3e-05 23.6 2.1 0.0048 16.6 1.3 2.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_7 PF13504.1 EKG13138.1 - 0.00039 20.1 1.6 4.3 7.9 0.1 4.1 4 0 0 4 4 4 2 Leucine rich repeat Acid_PPase PF12689.2 EKG13139.1 - 3.1e-62 209.1 0.0 3.7e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Pectate_lyase PF03211.8 EKG13140.1 - 6.7e-53 179.2 0.4 8.4e-53 178.9 0.2 1.1 1 0 0 1 1 1 1 Pectate lyase Ecm33 PF12454.3 EKG13140.1 - 0.075 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Beta-lactamase PF00144.19 EKG13141.1 - 1.2e-42 146.1 0.4 1.5e-42 145.7 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_1 PF00232.13 EKG13142.1 - 4.1e-77 259.2 0.0 8.2e-75 251.7 0.0 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EKG13142.1 - 0.0096 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Usp PF00582.21 EKG13143.1 - 2.4e-20 73.1 0.1 3.5e-13 49.9 0.0 2.7 2 0 0 2 2 2 2 Universal stress protein family CDC45 PF02724.9 EKG13143.1 - 0.087 10.8 3.1 0.18 9.8 2.1 1.5 1 0 0 1 1 1 0 CDC45-like protein AhpC-TSA_2 PF13911.1 EKG13145.1 - 2.8e-08 33.6 0.0 4.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EKG13145.1 - 2.4e-06 27.2 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKG13145.1 - 5.5e-05 22.7 0.0 0.00037 20.0 0.0 1.9 2 0 0 2 2 2 1 Redoxin Abhydrolase_6 PF12697.2 EKG13146.1 - 7.1e-18 65.3 0.2 1.2e-17 64.5 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG13146.1 - 2.9e-09 36.8 0.5 3e-05 23.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG13146.1 - 5e-09 36.0 0.4 7.1e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG13146.1 - 3.9e-05 23.4 0.2 6.5e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Putative lysophospholipase CN_hydrolase PF00795.17 EKG13147.1 - 4.4e-29 101.1 0.0 6.2e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Actino_peptide PF14408.1 EKG13148.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Amidohydro_2 PF04909.9 EKG13149.1 - 1.3e-40 139.7 0.1 1.5e-40 139.4 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Minor_capsid_2 PF11114.3 EKG13149.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Minor capsid protein IDO PF01231.13 EKG13150.1 - 1.6e-157 524.3 0.0 2e-157 524.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EKG13150.1 - 0.0011 17.5 0.0 0.092 11.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) Aminotran_5 PF00266.14 EKG13151.1 - 4e-06 25.8 0.0 5.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EKG13151.1 - 0.06 12.3 0.1 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 EKG13152.1 - 1.8e-12 46.7 1.4 2.5e-12 46.2 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG13152.1 - 8.5e-09 35.1 10.0 2.3e-08 33.7 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trp_syntA PF00290.15 EKG13153.1 - 2.2e-56 190.2 0.0 3.4e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EKG13153.1 - 1.5e-44 152.4 2.7 2.3e-44 151.8 1.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.2 EKG13154.1 - 9.9e-26 91.0 0.2 1.3e-25 90.6 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13154.1 - 1.5e-11 44.2 0.0 1.8e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG13154.1 - 0.0091 15.8 0.0 0.051 13.4 0.0 2.0 1 1 1 2 2 2 1 Putative lysophospholipase FAD_binding_3 PF01494.14 EKG13155.1 - 7.9e-49 166.6 0.0 9.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG13155.1 - 1.8e-06 27.1 0.1 3.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG13155.1 - 1.3e-05 24.2 1.0 0.004 16.1 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG13155.1 - 2.3e-05 24.3 0.0 5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG13155.1 - 0.0001 22.2 0.0 0.00025 20.9 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG13155.1 - 0.00089 19.6 0.1 0.0091 16.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG13155.1 - 0.001 17.9 0.7 0.0088 14.9 0.3 2.2 1 1 1 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EKG13155.1 - 0.0035 16.7 0.1 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EKG13155.1 - 0.0039 15.7 0.2 0.019 13.4 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EKG13155.1 - 0.0048 16.0 0.1 0.008 15.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 EKG13155.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EKG13155.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EKG13155.1 - 0.019 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EKG13155.1 - 0.019 14.4 0.0 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EKG13155.1 - 0.02 14.0 0.0 0.035 13.1 0.0 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 EKG13155.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.1 EKG13155.1 - 0.092 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EKG13155.1 - 0.093 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GMC_oxred_N PF00732.14 EKG13155.1 - 0.13 11.3 0.1 3 6.9 0.0 2.2 1 1 0 2 2 2 0 GMC oxidoreductase 3HCDH_N PF02737.13 EKG13156.1 - 3.9e-34 117.8 0.0 6.3e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EKG13156.1 - 6.4e-12 45.7 0.0 2e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EKG13156.1 - 1.2e-06 28.4 0.0 2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EKG13156.1 - 2e-06 27.6 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NHL PF01436.16 EKG13156.1 - 0.00062 19.5 0.1 0.029 14.3 0.0 3.1 3 0 0 3 3 3 1 NHL repeat F420_oxidored PF03807.12 EKG13156.1 - 0.0039 17.5 0.0 0.0093 16.3 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EKG13156.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EKG13156.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EKG13156.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 EKG13157.1 - 1.6e-60 205.4 0.1 2.7e-51 175.0 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKG13157.1 - 6.5e-10 38.9 0.2 1.6e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG13157.1 - 3.2e-07 30.5 0.1 2.4e-05 24.4 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG13157.1 - 0.00048 20.2 0.1 0.0074 16.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EKG13157.1 - 0.0029 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG13157.1 - 0.0037 17.6 0.2 0.74 10.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG13157.1 - 0.0051 15.7 1.1 0.21 10.4 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EKG13157.1 - 0.0084 15.0 0.1 0.015 14.1 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EKG13157.1 - 0.0094 15.7 0.1 0.52 10.0 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EKG13157.1 - 0.029 12.8 0.1 0.058 11.8 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EKG13157.1 - 0.037 13.0 0.1 0.068 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EKG13157.1 - 0.059 12.4 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_12 PF01670.11 EKG13159.1 - 3.8e-18 65.7 0.2 7.3e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Aldo_ket_red PF00248.16 EKG13160.1 - 5.2e-46 156.7 0.0 7.6e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family ER_lumen_recept PF00810.13 EKG13160.1 - 3.2e-35 121.7 4.5 4.7e-35 121.2 3.1 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EKG13160.1 - 0.0064 16.0 0.2 1.5 8.3 0.0 2.9 2 0 0 2 2 2 2 PQ loop repeat LicD PF04991.8 EKG13161.1 - 7.5e-36 124.1 11.1 7.7e-35 120.8 7.7 2.1 1 1 0 1 1 1 1 LicD family Peptidase_A17 PF05380.8 EKG13161.1 - 0.11 12.3 0.5 0.19 11.5 0.3 1.3 1 0 0 1 1 1 0 Pao retrotransposon peptidase Isochorismatase PF00857.15 EKG13162.1 - 7.7e-30 104.1 0.2 2.6e-29 102.3 0.2 1.7 1 1 0 1 1 1 1 Isochorismatase family NAD_binding_3 PF03447.11 EKG13162.1 - 0.019 15.3 0.0 0.051 13.9 0.0 1.6 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Transp_cyt_pur PF02133.10 EKG13164.1 - 1.8e-15 56.4 41.9 3.6e-15 55.4 29.1 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Caveolin PF01146.12 EKG13164.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 0 Caveolin eRF1_1 PF03463.10 EKG13165.1 - 3e-42 143.3 0.0 4.7e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EKG13165.1 - 3.2e-24 85.7 0.0 4.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EKG13165.1 - 5.8e-18 65.2 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 CAF-1_p150 PF11600.3 EKG13166.1 - 4.9 6.4 26.3 7.6 5.8 18.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Lipase_3 PF01764.20 EKG13167.1 - 2e-33 114.9 0.0 3.9e-33 114.0 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 3) Lipase3_N PF03893.11 EKG13167.1 - 4.8e-07 29.5 0.1 1e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 EKG13167.1 - 0.00029 20.2 0.5 0.0035 16.7 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EKG13167.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EKG13167.1 - 0.041 13.6 0.2 0.093 12.4 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 EKG13167.1 - 0.042 13.5 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 EKG13167.1 - 0.047 13.5 0.1 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 EKG13167.1 - 0.059 12.8 0.1 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Thioesterase PF00975.15 EKG13167.1 - 0.088 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Methyltransf_23 PF13489.1 EKG13168.1 - 4.1e-19 68.8 0.0 6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13168.1 - 1.7e-11 44.4 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13168.1 - 1.4e-09 38.4 0.0 5e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG13168.1 - 1.1e-08 35.4 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13168.1 - 1.2e-08 34.6 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG13168.1 - 0.00044 20.5 0.0 0.0008 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EKG13168.1 - 0.00067 18.8 0.0 0.00096 18.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EKG13168.1 - 0.0019 17.6 0.0 0.0043 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EKG13168.1 - 0.011 14.7 0.0 0.031 13.3 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EKG13168.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EKG13168.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EKG13168.1 - 0.023 13.8 0.0 0.075 12.1 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EKG13168.1 - 0.025 14.6 0.0 0.19 11.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EKG13168.1 - 0.028 13.8 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 EKG13168.1 - 0.028 13.5 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase GidB PF02527.10 EKG13168.1 - 0.036 13.2 0.0 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Peptidase_M17 PF00883.16 EKG13168.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, catalytic domain PCMT PF01135.14 EKG13168.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ABC_tran PF00005.22 EKG13169.1 - 4e-32 111.3 1.3 7e-32 110.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EKG13169.1 - 7.3e-31 107.5 7.5 7.3e-31 107.5 5.2 2.2 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.14 EKG13169.1 - 1.3e-06 27.7 0.0 4.7e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG13169.1 - 0.0003 20.8 0.0 0.05 13.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EKG13169.1 - 0.0029 17.5 0.8 0.038 13.9 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Oxidored_q3 PF00499.15 EKG13169.1 - 0.0082 15.9 0.3 0.0082 15.9 0.2 3.8 4 1 1 5 5 5 2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF258 PF03193.11 EKG13169.1 - 0.0098 15.0 0.0 0.026 13.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKG13169.1 - 0.03 14.4 0.2 0.2 11.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EKG13169.1 - 0.069 12.6 0.1 0.069 12.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG13169.1 - 0.11 12.5 0.1 0.62 10.0 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 EKG13170.1 - 7.7e-14 50.9 0.6 7.7e-12 44.6 0.2 3.0 2 0 0 2 2 2 1 WD domain, G-beta repeat eIF2A PF08662.6 EKG13170.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Shisa PF13908.1 EKG13171.1 - 0.026 14.7 0.0 0.03 14.4 0.0 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Glyco_hydro_16 PF00722.16 EKG13172.1 - 6.9e-39 133.0 4.0 1.1e-38 132.4 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF515 PF04415.7 EKG13172.1 - 0.44 8.7 4.7 0.68 8.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PAM2 PF07145.10 EKG13173.1 - 0.011 15.2 0.1 0.057 12.9 0.0 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region APG6 PF04111.7 EKG13173.1 - 0.74 8.7 4.2 1.1 8.2 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 XLF PF09302.6 EKG13174.1 - 3e-24 85.7 0.5 3.8e-24 85.3 0.0 1.5 2 0 0 2 2 2 1 XLF (XRCC4-like factor) Cactin_mid PF10312.4 EKG13175.1 - 1.3e-63 213.6 4.0 2.5e-63 212.7 2.8 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EKG13175.1 - 2.7e-56 188.5 5.8 4.1e-56 187.9 4.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Fork_head PF00250.13 EKG13176.1 - 2.4e-19 69.1 0.0 3.9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Fork head domain Amidase PF01425.16 EKG13177.1 - 1.8e-89 300.6 0.0 2.4e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Glyco_trans_4_4 PF13579.1 EKG13177.1 - 0.034 14.2 0.2 0.077 13.1 0.2 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Fn3-like PF14310.1 EKG13177.1 - 0.091 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III-like domain GFA PF04828.9 EKG13178.1 - 1.4e-12 47.4 0.3 2.5e-12 46.5 0.0 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PMSR PF01625.16 EKG13179.1 - 2.4e-59 199.6 0.3 2.8e-59 199.4 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase JAB PF01398.16 EKG13180.1 - 5.1e-35 119.6 0.0 9.5e-35 118.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EKG13180.1 - 8.6e-27 93.5 1.2 1.9e-26 92.4 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EKG13180.1 - 6.2e-09 35.3 0.0 1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Hist_deacetyl PF00850.14 EKG13181.1 - 2.9e-79 266.6 0.0 4.8e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain 2-Hacid_dh_C PF02826.14 EKG13183.1 - 2.2e-39 134.4 0.0 3e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG13183.1 - 3.2e-10 39.5 0.0 3.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GFO_IDH_MocA PF01408.17 EKG13183.1 - 0.0021 18.5 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.10 EKG13183.1 - 0.0035 17.1 0.1 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase tRNA-synt_2d PF01409.15 EKG13184.1 - 1.3e-82 276.7 0.0 1.7e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EKG13184.1 - 1.7e-07 30.3 0.4 0.00022 20.0 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EKG13184.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Tim17 PF02466.14 EKG13185.1 - 0.055 13.5 5.0 0.43 10.6 3.8 2.0 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF3405 PF11885.3 EKG13186.1 - 8.3e-193 641.1 6.1 1.3e-192 640.4 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Alk_phosphatase PF00245.15 EKG13190.1 - 3.7e-107 358.6 0.0 4.7e-107 358.2 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EKG13190.1 - 3e-05 23.5 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EKG13190.1 - 0.0012 18.5 0.3 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Adeno_E3 PF06040.6 EKG13190.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E3 protein RNA_pol_Rpc34 PF05158.7 EKG13191.1 - 6.9e-74 248.9 0.0 8.5e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit TrmB PF01978.14 EKG13191.1 - 0.025 14.2 0.0 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PadR PF03551.9 EKG13191.1 - 0.044 13.5 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family HTH_36 PF13730.1 EKG13191.1 - 0.054 13.6 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RPA_C PF08784.6 EKG13191.1 - 0.066 13.6 0.0 0.72 10.2 0.0 2.4 2 1 1 3 3 3 0 Replication protein A C terminal B-block_TFIIIC PF04182.7 EKG13191.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Rrf2 PF02082.15 EKG13191.1 - 0.2 11.7 0.7 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator Transp_cyt_pur PF02133.10 EKG13192.1 - 9.2e-48 162.8 34.4 1.1e-47 162.6 23.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1129 PF06570.6 EKG13192.1 - 4.8 6.4 9.6 6 6.1 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) GIT_SHD PF08518.6 EKG13193.1 - 2.4e-20 71.5 10.5 3.6e-14 51.7 1.8 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT ERM PF00769.14 EKG13193.1 - 0.01 15.3 37.6 0.11 12.0 10.4 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family WHEP-TRS PF00458.15 EKG13193.1 - 0.024 14.3 1.1 0.055 13.1 0.8 1.6 1 0 0 1 1 1 0 WHEP-TRS domain Syntaxin PF00804.20 EKG13193.1 - 0.036 14.2 25.7 1.3 9.1 0.0 4.6 2 1 2 4 4 4 0 Syntaxin IncA PF04156.9 EKG13193.1 - 0.6 9.6 44.7 0.74 9.3 14.0 2.9 2 1 1 3 3 3 0 IncA protein CENP-F_leu_zip PF10473.4 EKG13193.1 - 0.74 9.6 37.0 0.061 13.1 6.6 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EKG13193.1 - 0.91 6.7 28.4 1.5 6.0 19.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4404 PF14357.1 EKG13193.1 - 2.8 8.4 28.2 1.1 9.6 3.8 4.2 3 1 2 5 5 5 0 Domain of unknown function (DUF4404) DUF972 PF06156.8 EKG13193.1 - 6.6 7.1 24.0 0.42 10.9 2.5 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) LMBR1 PF04791.11 EKG13193.1 - 9.8 4.6 16.7 4 5.8 6.9 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein ING PF12998.2 EKG13194.1 - 4.7e-23 81.4 4.7 8e-23 80.7 3.3 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EKG13194.1 - 4.9e-09 35.7 8.3 8.5e-09 34.9 5.7 1.4 1 0 0 1 1 1 1 PHD-finger Hist_deacetyl PF00850.14 EKG13195.1 - 2.1e-77 260.4 0.0 3.2e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain HTH_38 PF13936.1 EKG13195.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Pkinase PF00069.20 EKG13196.1 - 1.9e-71 240.2 0.0 2.8e-71 239.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG13196.1 - 2.5e-36 125.0 0.0 7e-36 123.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG13196.1 - 0.0014 17.6 0.7 0.58 9.0 0.0 2.6 3 0 0 3 3 3 2 Kinase-like p450 PF00067.17 EKG13197.1 - 5.6e-35 120.7 0.1 6.2e-34 117.3 0.0 2.5 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EKG13198.1 - 4.2e-29 100.7 0.3 5.6e-29 100.3 0.2 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG13198.1 - 7.7e-19 68.8 0.1 9.8e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MGS PF02142.17 EKG13198.1 - 0.033 14.1 0.6 0.39 10.6 0.4 2.2 1 1 0 1 1 1 0 MGS-like domain MFS_1 PF07690.11 EKG13199.1 - 4.2e-46 157.2 40.9 4.2e-46 157.2 28.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG13199.1 - 8.8e-16 57.5 2.3 8.8e-16 57.5 1.6 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter Peptidase_S28 PF05577.7 EKG13200.1 - 1.4e-46 158.9 0.2 5.3e-46 157.0 0.1 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Fungal_trans PF04082.13 EKG13200.1 - 1.7e-25 89.3 0.0 3.3e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TEX13 PF15186.1 EKG13200.1 - 0.083 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family IDO PF01231.13 EKG13200.1 - 0.12 10.7 0.0 9.3 4.5 0.0 2.1 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase Lipoprotein_18 PF06804.6 EKG13202.1 - 0.013 14.2 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 NlpB/DapX lipoprotein Rick_17kDa_Anti PF05433.10 EKG13203.1 - 0.00094 18.8 9.7 0.0015 18.1 6.8 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EKG13203.1 - 0.0041 16.7 1.6 0.008 15.8 1.1 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EKG13203.1 - 0.061 12.9 4.6 0.12 12.0 3.2 1.5 1 0 0 1 1 1 0 Glycine zipper DUF3810 PF12725.2 EKG13203.1 - 0.088 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Transgly_assoc PF04226.8 EKG13203.1 - 0.61 10.2 2.4 0.95 9.5 1.7 1.2 1 0 0 1 1 1 0 Transglycosylase associated protein cNMP_binding PF00027.24 EKG13204.1 - 8.4e-36 121.6 0.0 8.5e-19 67.1 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EKG13204.1 - 1.4e-12 46.2 6.1 1.7 8.9 0.0 8.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 EKG13204.1 - 3e-08 32.5 1.0 31 5.1 0.0 8.3 7 2 1 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.1 EKG13204.1 - 1.2e-07 31.3 0.0 0.082 12.6 0.0 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EKG13204.1 - 2.3e-05 23.9 0.0 1.4 8.6 0.0 5.4 4 1 3 7 7 7 1 Leucine Rich repeats (2 copies) F-box PF00646.28 EKG13204.1 - 3.7e-05 23.2 3.3 6.3e-05 22.5 0.2 2.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EKG13204.1 - 8.9e-05 22.1 0.0 0.00026 20.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like Ste50p-SAM PF09235.5 EKG13204.1 - 0.097 12.7 3.0 6.1 6.9 0.1 4.0 5 0 0 5 5 5 0 Ste50p, sterile alpha motif LRR_7 PF13504.1 EKG13204.1 - 0.24 11.7 12.0 28 5.4 0.0 7.0 9 0 0 9 9 9 0 Leucine rich repeat RNase_PH PF01138.16 EKG13205.1 - 1.4e-37 128.9 0.0 2e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EKG13205.1 - 0.016 15.1 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 adh_short_C2 PF13561.1 EKG13206.1 - 1.7e-25 90.2 0.1 2e-25 89.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG13206.1 - 1.5e-24 86.8 2.3 1.6e-24 86.7 1.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG13206.1 - 7.9e-11 41.9 0.4 1.3e-10 41.2 0.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG13206.1 - 0.00013 21.4 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 EKG13206.1 - 0.0052 16.6 0.8 0.01 15.6 0.1 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EKG13206.1 - 0.09 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EKG13206.1 - 0.12 11.1 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_hydro_43 PF04616.9 EKG13208.1 - 0.00011 21.4 0.4 0.00016 20.8 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SH3_9 PF14604.1 EKG13209.1 - 3.8e-11 42.4 0.0 7.9e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG13209.1 - 1.1e-10 40.6 0.0 2.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EKG13209.1 - 7.2e-08 31.8 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ssu72 PF04722.8 EKG13210.1 - 2.4e-85 284.8 0.0 2.8e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein ORC6 PF05460.8 EKG13211.1 - 0.1 11.7 2.9 0.12 11.4 2.0 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SdpI PF13630.1 EKG13212.1 - 0.77 9.5 8.0 0.084 12.5 0.5 2.4 2 1 0 2 2 2 0 SdpI/YhfL protein family DUF4231 PF14015.1 EKG13212.1 - 0.96 9.4 3.8 0.37 10.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1469 PF07332.6 EKG13212.1 - 2 8.1 7.8 0.34 10.6 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Fungal_trans_2 PF11951.3 EKG13213.1 - 2.5e-06 26.3 0.1 4.4e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EKG13215.1 - 9.1e-14 50.8 0.4 1.1e-13 50.6 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Peptidase_M11 PF05548.6 EKG13215.1 - 0.055 12.3 0.1 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 Gametolysin peptidase M11 Glyco_hydro_3_C PF01915.17 EKG13216.1 - 2.1e-57 194.2 0.6 3.5e-57 193.5 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 EKG13216.1 - 1.1e-53 182.1 0.0 2.2e-53 181.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 EKG13216.1 - 9.5e-24 83.1 0.1 3.4e-23 81.3 0.1 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain GMC_oxred_N PF00732.14 EKG13217.1 - 3.5e-40 138.0 0.0 1e-39 136.4 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG13217.1 - 2.3e-06 26.7 1.3 0.0006 18.8 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG13217.1 - 7.9e-06 24.9 1.2 0.025 13.4 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EKG13217.1 - 0.0002 21.3 0.2 0.0025 17.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG13217.1 - 0.0019 18.2 1.8 0.018 15.0 1.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG13217.1 - 0.023 13.6 0.2 0.035 13.0 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EKG13217.1 - 0.14 11.8 0.3 1.1 9.0 0.1 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Sugar_tr PF00083.19 EKG13218.1 - 2e-33 115.6 29.8 4.8e-17 61.6 7.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG13218.1 - 8e-26 90.5 40.1 1.1e-15 57.1 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG13218.1 - 3.7e-08 32.1 27.3 2.8e-06 25.9 3.8 2.6 1 1 0 2 2 2 2 MFS/sugar transport protein RseC_MucC PF04246.7 EKG13218.1 - 2.2 7.8 5.2 5.1 6.6 0.1 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Peptidase_M24 PF00557.19 EKG13219.1 - 1e-25 90.5 0.0 1.5e-24 86.7 0.0 2.0 1 1 0 1 1 1 1 Metallopeptidase family M24 ETF PF01012.16 EKG13220.1 - 0.062 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain FAD_binding_3 PF01494.14 EKG13221.1 - 9.7e-68 228.7 0.0 8.7e-67 225.6 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EKG13221.1 - 0.0033 16.5 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EKG13221.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG13221.1 - 0.011 14.6 0.5 0.21 10.4 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EKG13221.1 - 0.011 15.7 0.1 0.034 14.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG13221.1 - 0.026 13.4 0.2 0.05 12.5 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EKG13221.1 - 0.035 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG13221.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG13221.1 - 0.097 11.1 0.0 0.15 10.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein B-block_TFIIIC PF04182.7 EKG13222.1 - 0.037 13.8 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Myb_DNA-bind_6 PF13921.1 EKG13223.1 - 1.3e-35 121.2 8.6 8.7e-16 57.7 0.2 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG13223.1 - 3.6e-31 106.9 9.2 6e-10 39.0 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EKG13223.1 - 0.0069 16.5 5.3 0.98 9.6 0.1 3.3 2 1 1 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.1 EKG13223.1 - 0.39 10.8 10.4 11 6.2 0.9 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EKG13223.1 - 1.2 9.1 13.7 20 5.1 1.1 4.5 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain AMP-binding PF00501.23 EKG13224.1 - 5.3e-38 130.5 0.1 5.8e-37 127.0 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKG13224.1 - 4.5e-26 91.2 0.0 6.5e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EKG13224.1 - 8.3e-09 35.2 0.0 2.2e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EKG13224.1 - 8.5e-07 29.1 0.0 4e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 EKG13224.1 - 0.0053 16.6 2.9 0.084 12.7 0.2 2.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG13224.1 - 0.012 15.2 1.7 0.03 13.9 0.2 2.5 2 0 0 2 2 2 0 KR domain ketoacyl-synt PF00109.21 EKG13225.1 - 3.4e-64 216.7 0.0 5e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EKG13225.1 - 0.00027 19.9 0.1 0.00044 19.3 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Acyl_transf_1 PF00698.16 EKG13226.1 - 1.1e-52 179.3 0.0 2.6e-52 178.1 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EKG13226.1 - 6.4e-25 87.9 0.0 1.1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EKG13226.1 - 8.6e-21 73.9 2.1 4.6e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EKG13228.1 - 3.5e-22 79.4 0.0 5.1e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13228.1 - 3.5e-12 46.2 0.0 5.2e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG13228.1 - 1.5e-08 34.4 0.0 3.4e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 EKG13228.1 - 2.1e-05 23.9 0.0 0.00049 19.4 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Peptidase_S9 PF00326.16 EKG13228.1 - 5.6e-05 22.4 0.0 0.063 12.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family PGAP1 PF07819.8 EKG13228.1 - 0.00025 20.7 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 EKG13228.1 - 0.0012 18.1 0.0 0.052 12.8 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EKG13228.1 - 0.0023 17.4 0.1 0.0066 15.9 0.0 1.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EKG13228.1 - 0.0028 17.1 0.1 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EKG13228.1 - 0.0093 15.6 0.1 0.33 10.6 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EKG13228.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase adh_short PF00106.20 EKG13229.1 - 3.4e-25 88.9 4.2 4.9e-25 88.3 2.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13229.1 - 9.1e-11 41.7 0.8 1.5e-10 41.0 0.5 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG13229.1 - 1.8e-10 40.9 0.1 2.4e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EKG13229.1 - 2.2e-06 27.0 0.0 2.9e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EKG13229.1 - 7.1e-05 22.8 1.2 0.00013 22.0 0.9 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKG13229.1 - 0.004 16.9 0.1 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG13229.1 - 0.0068 15.8 1.5 0.013 14.9 1.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EKG13229.1 - 0.05 13.1 1.4 0.095 12.2 1.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase adh_short PF00106.20 EKG13230.1 - 2.3e-22 79.6 0.2 5.6e-22 78.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG13230.1 - 7.6e-09 35.6 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG13230.1 - 2.3e-08 33.8 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG13230.1 - 3e-06 27.3 0.1 1.7e-05 24.9 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding ADH_zinc_N PF00107.21 EKG13230.1 - 1.5e-05 24.5 0.6 0.00015 21.3 0.1 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EKG13230.1 - 0.0022 17.7 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG13230.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EKG13230.1 - 0.023 13.8 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EKG13230.1 - 0.027 13.3 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.20 EKG13231.1 - 2.9e-15 56.5 0.8 5.2e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13231.1 - 1.1e-05 25.1 0.1 1.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EKG13231.1 - 8.1e-05 21.9 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) FAD_binding_4 PF01565.18 EKG13232.1 - 2.8e-24 85.1 0.3 4.5e-24 84.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG13232.1 - 0.0061 16.4 0.0 0.02 14.7 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_S8 PF00082.17 EKG13235.1 - 3.1e-09 36.4 0.1 4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Subtilase family DUF4129 PF13559.1 EKG13237.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF485 PF04341.7 EKG13237.1 - 0.71 9.6 4.8 1.6 8.5 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF605 PF04652.11 EKG13237.1 - 2.1 7.6 8.9 3.1 7.1 6.2 1.2 1 0 0 1 1 1 0 Vta1 like Aha1_N PF09229.6 EKG13238.1 - 2.2e-37 127.9 0.1 3.5e-37 127.2 0.1 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EKG13238.1 - 3.2e-16 59.5 2.1 7.2e-16 58.4 1.4 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein GST_C PF00043.20 EKG13240.1 - 1.3e-09 37.8 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG13240.1 - 4e-09 36.5 0.0 6.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG13240.1 - 1e-07 32.0 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG13240.1 - 6.5e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG13240.1 - 7.4e-06 25.7 0.0 1.4e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG13240.1 - 2.3e-05 24.7 0.1 3.8e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.19 EKG13241.1 - 3.4e-28 98.4 32.0 6.6e-15 54.6 11.2 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG13241.1 - 8.8e-15 54.2 41.5 1.6e-07 30.3 15.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3431 PF11913.3 EKG13243.1 - 1e-76 257.3 0.1 1.4e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Glyco_hydro_18 PF00704.23 EKG13244.1 - 3.1e-15 56.4 2.2 3.1e-15 56.4 1.5 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EKG13244.1 - 0.0066 16.3 20.8 0.025 14.5 14.0 2.4 1 1 0 1 1 1 1 Chitin recognition protein DUF1445 PF07286.7 EKG13245.1 - 9.6e-51 171.1 0.0 1.3e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.11 EKG13246.1 - 3e-37 128.1 22.6 3.6e-37 127.8 15.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EKG13246.1 - 0.004 16.6 3.2 0.004 16.6 2.2 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 EKG13247.1 - 4e-21 75.0 0.0 7.5e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EKG13248.1 - 8e-35 120.2 3.8 1.6e-32 112.7 0.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG13248.1 - 3.8e-05 22.5 1.3 0.0026 16.5 0.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.7 EKG13249.1 - 0.00019 21.8 0.0 0.00042 20.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG13249.1 - 0.088 11.9 0.0 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Pyridox_ox_2 PF12900.2 EKG13250.1 - 1.9e-32 112.0 0.0 4.1e-32 110.9 0.0 1.5 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase HECT PF00632.20 EKG13251.1 - 5e-85 285.4 0.0 1e-84 284.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EKG13251.1 - 0.0013 18.1 1.5 0.0054 16.2 1.1 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif dsrm PF00035.20 EKG13252.1 - 0.00014 22.3 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EKG13252.1 - 0.00085 19.5 0.5 0.0018 18.5 0.4 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Prenyltrans PF00432.16 EKG13254.1 - 1.4e-36 123.7 14.9 1.1e-09 37.6 0.6 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKG13254.1 - 2.6e-21 76.1 0.0 3.7e-14 53.0 0.0 3.3 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EKG13254.1 - 0.0012 18.8 0.0 0.045 13.7 0.0 2.6 2 1 0 2 2 2 1 Prenyltransferase-like Subtilosin_A PF11420.3 EKG13255.1 - 0.29 11.1 1.8 6.9 6.7 0.0 3.0 2 1 0 2 2 2 0 Bacteriocin subtilosin A Zn_clus PF00172.13 EKG13256.1 - 0.0044 16.8 7.8 0.0097 15.7 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4260 PF14079.1 EKG13257.1 - 0.076 12.8 0.1 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) Pro_CA PF00484.14 EKG13264.1 - 6.7e-43 146.3 0.0 8e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Hemerythrin PF01814.18 EKG13265.1 - 7.7e-10 39.0 0.6 1e-09 38.6 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HSP70 PF00012.15 EKG13266.1 - 6.8e-273 906.0 5.8 7.7e-273 905.9 4.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKG13266.1 - 5.4e-17 61.3 0.0 4.6e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EKG13266.1 - 0.0012 18.0 0.1 0.018 14.1 0.0 2.2 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EKG13266.1 - 0.0028 17.3 0.0 0.0071 15.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EKG13266.1 - 0.21 11.4 3.8 13 5.6 2.6 3.3 1 1 0 1 1 1 0 Cell division protein FtsA DUF3128 PF11326.3 EKG13267.1 - 1.2e-30 105.3 2.5 1.9e-30 104.8 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF1162 PF06650.7 EKG13268.1 - 3.9e-92 308.3 0.0 2.5e-90 302.4 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EKG13268.1 - 4.7e-41 139.0 0.0 1.5e-40 137.3 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EKG13268.1 - 0.0017 18.4 0.1 0.021 14.9 0.0 2.7 3 0 0 3 3 3 1 ATG C terminal domain DUF3040 PF11239.3 EKG13268.1 - 0.17 11.9 0.5 0.43 10.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) p450 PF00067.17 EKG13269.1 - 1.1e-48 165.9 0.0 1.4e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ubiquitin PF00240.18 EKG13270.1 - 4.8e-136 442.3 23.5 1.1e-33 114.4 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EKG13270.1 - 2.2e-78 257.9 21.1 4.3e-19 67.9 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKG13270.1 - 2.6e-24 85.2 11.1 0.00015 21.9 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EKG13270.1 - 5.2e-22 78.2 1.5 0.00071 19.3 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EKG13270.1 - 5.2e-14 52.0 2.9 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EKG13270.1 - 8.1e-14 51.5 2.4 0.13 12.5 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EKG13270.1 - 9.7e-11 41.5 0.0 1.5 8.8 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EKG13270.1 - 1.6e-06 27.9 5.8 4.5 7.2 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EKG13270.1 - 5.3e-06 25.7 0.5 2 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EKG13270.1 - 6.8e-05 22.5 5.3 14 5.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EKG13270.1 - 0.00045 18.6 13.5 2.3 6.4 0.2 5.7 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EKG13270.1 - 0.0011 18.4 0.0 48 3.3 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EKG13270.1 - 0.0019 18.5 0.6 1e+02 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 EKG13270.1 - 0.0055 16.7 5.2 53 4.0 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EKG13270.1 - 0.023 14.5 14.3 7.9 6.4 0.2 4.4 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EKG13270.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EKG13270.1 - 0.037 14.0 7.8 44 4.1 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EKG13270.1 - 0.071 13.1 12.4 42 4.2 0.1 5.9 4 4 0 4 4 4 0 FERM N-terminal domain DUF3781 PF12636.2 EKG13270.1 - 0.4 10.6 7.4 1e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 EKG13270.1 - 1.8 8.2 8.3 1e+02 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 EKG13270.1 - 9.3 5.9 12.2 70 3.1 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 Aldo_ket_red PF00248.16 EKG13271.1 - 1.8e-23 82.8 0.0 2.1e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Xan_ur_permease PF00860.15 EKG13272.1 - 1.5e-25 89.5 32.4 2.3e-24 85.6 20.9 2.6 2 1 0 2 2 2 1 Permease family PhyH PF05721.8 EKG13273.1 - 3e-25 89.5 0.1 4.4e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1751 PF08551.5 EKG13275.1 - 0.0015 18.7 0.8 0.0015 18.7 0.6 1.8 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Microtub_assoc PF07989.6 EKG13276.1 - 1.2e-07 31.4 8.6 3.4e-05 23.5 5.9 2.6 1 1 0 1 1 1 1 Microtubule associated KLRAQ PF10205.4 EKG13276.1 - 0.0023 17.9 5.1 0.0072 16.3 3.5 1.9 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Fmp27_WPPW PF10359.4 EKG13276.1 - 0.4 9.0 6.0 0.61 8.4 4.2 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.10 EKG13276.1 - 0.62 9.5 4.9 0.34 10.4 0.9 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EKG13276.1 - 0.72 10.1 10.6 7.9 6.8 5.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Cluap1 PF10234.4 EKG13276.1 - 0.86 8.7 7.8 1.3 8.1 5.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF342 PF03961.8 EKG13276.1 - 1.6 7.0 3.5 2.4 6.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_GP20 PF06810.6 EKG13276.1 - 6.1 6.2 10.6 15 4.9 7.1 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 IncA PF04156.9 EKG13276.1 - 7.4 6.1 15.1 6.1 6.3 9.4 1.5 1 1 0 1 1 1 0 IncA protein adh_short PF00106.20 EKG13277.1 - 0.0014 18.5 0.0 0.1 12.5 0.0 3.1 2 1 0 2 2 2 1 short chain dehydrogenase IDEAL PF08858.5 EKG13277.1 - 0.11 12.0 0.5 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 IDEAL domain FGGY_C PF02782.11 EKG13278.1 - 4.4e-76 254.9 0.5 7.3e-76 254.2 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EKG13278.1 - 8.1e-60 202.1 0.0 1.1e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF3429 PF11911.3 EKG13279.1 - 3e-40 137.4 13.6 4.2e-40 137.0 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Ribosomal_S7 PF00177.16 EKG13280.1 - 3e-27 95.0 0.0 4.8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AOX PF01786.12 EKG13281.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Alternative oxidase Baculo_PEP_C PF04513.7 EKG13281.1 - 0.37 10.6 0.0 0.37 10.6 0.0 2.8 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF924 PF06041.6 EKG13282.1 - 4.3e-42 143.9 0.0 1e-40 139.5 0.0 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Amidase PF01425.16 EKG13283.1 - 1.4e-94 317.4 0.1 1.7e-94 317.1 0.1 1.0 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.16 EKG13284.1 - 3.3e-11 42.8 0.0 6.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HTH_21 PF13276.1 EKG13284.1 - 0.097 12.6 0.2 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 HTH-like domain MFS_1 PF07690.11 EKG13285.1 - 6e-31 107.4 33.8 3.3e-29 101.7 23.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily GCFC PF07842.7 EKG13286.1 - 1.2e-77 260.9 6.3 1.7e-77 260.4 4.4 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EKG13286.1 - 8.5e-17 60.6 3.1 1.5e-16 59.8 2.1 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EKG13286.1 - 4.5e-07 29.6 1.0 4.5e-07 29.6 0.7 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site GAS PF13851.1 EKG13286.1 - 0.04 13.1 5.4 0.092 11.9 3.7 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DNA_pol_phi PF04931.8 EKG13288.1 - 0.41 8.3 2.1 0.49 8.1 1.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3328 PF11807.3 EKG13289.1 - 1.4e-46 158.9 0.3 2e-46 158.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_M41 PF01434.13 EKG13290.1 - 5.8e-70 235.0 1.3 9.9e-70 234.3 0.9 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EKG13290.1 - 5.3e-43 146.3 0.0 2.1e-42 144.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG13290.1 - 5.9e-06 27.0 0.1 2.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG13290.1 - 9.9e-06 25.6 0.6 0.00017 21.6 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EKG13290.1 - 3.3e-05 22.7 0.0 6.7e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EKG13290.1 - 3.5e-05 22.9 0.0 7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EKG13290.1 - 3.6e-05 23.5 0.0 0.0001 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG13290.1 - 7.3e-05 22.9 0.6 0.0079 16.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKG13290.1 - 0.00095 18.6 1.4 0.067 12.5 0.2 2.8 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG13290.1 - 0.00097 18.8 0.2 0.0034 17.1 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EKG13290.1 - 0.0026 17.6 0.0 0.0068 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EKG13290.1 - 0.003 17.0 0.1 0.0063 15.9 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EKG13290.1 - 0.0093 15.0 0.5 0.021 13.9 0.2 1.7 1 1 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EKG13290.1 - 0.017 15.0 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EKG13290.1 - 0.02 14.0 0.4 0.043 12.9 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI BAG PF02179.11 EKG13290.1 - 0.027 14.5 0.6 0.27 11.3 0.0 2.5 2 0 0 2 2 2 0 BAG domain AAA_18 PF13238.1 EKG13290.1 - 0.031 14.6 0.0 0.095 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EKG13290.1 - 0.034 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EKG13290.1 - 0.08 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EKG13290.1 - 0.085 12.8 0.0 0.28 11.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain SpoU_sub_bind PF08032.7 EKG13290.1 - 0.096 12.8 0.2 12 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Acyltransferase PF01553.16 EKG13291.1 - 3.2e-07 29.8 0.0 3.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Acyltransferase Thiolase_N PF00108.18 EKG13294.1 - 1.5e-75 253.6 0.6 2.6e-75 252.8 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EKG13294.1 - 4.9e-45 151.9 1.4 5.6e-45 151.7 0.2 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EKG13294.1 - 0.092 12.2 3.7 0.49 9.8 1.3 2.7 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain WWbp PF10349.4 EKG13295.1 - 5.9e-18 65.8 11.2 1.1e-17 64.9 5.9 2.3 2 1 0 2 2 2 1 WW-domain ligand protein Na_Ca_ex PF01699.19 EKG13297.1 - 8e-48 161.6 35.3 2e-26 92.2 7.5 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 EKG13297.1 - 0.1 12.0 0.1 0.1 12.0 0.1 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4131) DUF3278 PF11683.3 EKG13297.1 - 4.4 7.2 8.0 1.3 8.9 0.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3278) Piwi PF02171.12 EKG13298.1 - 5.5e-78 261.9 0.0 7.3e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EKG13298.1 - 1e-13 50.4 0.0 2.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EKG13298.1 - 2.8e-12 46.1 0.0 1.1e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 PAZ domain Glyco_hydro_81 PF03639.8 EKG13299.1 - 6.6e-208 692.0 2.5 8.6e-208 691.7 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Utp14 PF04615.8 EKG13300.1 - 3.3e-205 683.5 67.7 3.3e-205 683.5 46.9 2.0 1 1 1 2 2 2 1 Utp14 protein MRP-L27 PF09809.4 EKG13301.1 - 9.5e-18 63.8 1.2 1.2e-17 63.4 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 YkuD PF03734.9 EKG13301.1 - 0.073 13.3 0.6 0.082 13.1 0.4 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain Ish1 PF10281.4 EKG13302.1 - 0.095 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Methyltransf_23 PF13489.1 EKG13303.1 - 1.2e-22 80.3 0.0 1.5e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13303.1 - 1.3e-18 67.2 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG13303.1 - 6e-16 58.7 0.0 8.2e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13303.1 - 1.4e-14 53.9 0.0 1.8e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13303.1 - 7.4e-12 45.8 0.0 1e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EKG13303.1 - 5.6e-11 41.7 0.0 7.5e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EKG13303.1 - 4.2e-10 39.8 0.0 5.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG13303.1 - 1.8e-07 31.1 0.0 5.1e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EKG13303.1 - 1.1e-05 24.8 0.0 1.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 EKG13303.1 - 1.8e-05 23.9 0.0 2.5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EKG13303.1 - 5.6e-05 22.4 0.0 6.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EKG13303.1 - 0.0021 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EKG13303.1 - 0.0026 16.8 0.0 0.016 14.2 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EKG13303.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EKG13303.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Aminotran_1_2 PF00155.16 EKG13304.1 - 1.2e-36 126.4 0.0 1.5e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ING PF12998.2 EKG13305.1 - 3.8e-08 33.5 2.8 9.9e-07 29.0 1.9 2.5 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EKG13305.1 - 1.9e-07 30.6 1.8 3.3e-07 29.8 1.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EKG13305.1 - 0.017 15.2 0.2 0.04 14.0 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF972 PF06156.8 EKG13305.1 - 0.36 11.1 2.3 12 6.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ribosomal_L7Ae PF01248.21 EKG13306.1 - 5.6e-21 73.8 0.3 9.4e-21 73.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family OCD_Mu_crystall PF02423.10 EKG13307.1 - 2.7e-16 59.2 0.0 2e-09 36.6 0.0 3.1 2 1 1 3 3 3 3 Ornithine cyclodeaminase/mu-crystallin family Glyco_hydro_31 PF01055.21 EKG13309.1 - 2.1e-47 161.9 0.4 2.7e-47 161.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG13309.1 - 8.9e-17 60.7 0.0 8.9e-17 60.7 0.0 2.2 3 0 0 3 3 3 1 Galactose mutarotase-like DUF3437 PF11919.3 EKG13310.1 - 4.7e-31 106.3 0.0 1.4e-30 104.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EKG13310.1 - 0.0023 17.8 0.1 23 5.4 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat Sld5 PF05916.6 EKG13311.1 - 3.4e-16 59.4 0.0 4.5e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Prenyltransf PF01255.14 EKG13312.1 - 9.7e-86 286.4 0.0 1.2e-85 286.1 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CENP-Q PF13094.1 EKG13313.1 - 0.042 13.8 0.4 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Peptidase_S10 PF00450.17 EKG13315.1 - 9.3e-51 173.2 0.0 1.4e-50 172.7 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_8 PF13523.1 EKG13316.1 - 1.5e-40 138.5 0.0 2.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG13316.1 - 0.00053 20.1 0.0 0.00082 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sod_Fe_C PF02777.13 EKG13317.1 - 1.4e-39 134.2 1.5 2.2e-39 133.5 0.3 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EKG13317.1 - 5.4e-28 97.0 2.3 9.6e-28 96.2 1.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 EKG13317.1 - 0.024 13.6 2.1 0.19 10.8 0.0 3.0 3 1 1 4 4 4 0 Immunity protein 15 Arc PF03869.9 EKG13318.1 - 0.062 12.9 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Arc-like DNA binding domain DUF1295 PF06966.7 EKG13319.1 - 5.8e-44 150.1 0.0 3.7e-42 144.2 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EKG13319.1 - 0.00016 21.7 0.2 0.0017 18.3 0.0 2.7 2 1 1 3 3 3 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EKG13319.1 - 0.00043 20.0 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Acyl_transf_3 PF01757.17 EKG13319.1 - 0.0027 16.6 2.6 0.073 11.8 0.3 2.2 1 1 1 2 2 2 2 Acyltransferase family ICMT PF04140.9 EKG13319.1 - 0.0068 16.5 0.0 0.054 13.6 0.0 2.5 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TctB PF07331.6 EKG13319.1 - 0.055 13.1 7.5 0.019 14.6 1.7 2.5 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Ribonuclease_T2 PF00445.13 EKG13322.1 - 3.4e-30 105.0 0.2 4.4e-30 104.7 0.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family SET PF00856.23 EKG13323.1 - 8.1e-08 32.7 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 SET domain UCR_hinge PF02320.11 EKG13324.1 - 1.6e-12 47.1 8.2 3e-12 46.2 5.7 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4045 PF13254.1 EKG13324.1 - 0.99 8.6 13.0 1.2 8.3 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Herpes_TAF50 PF03326.8 EKG13324.1 - 1.3 7.9 8.6 1.5 7.6 6.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) IncA PF04156.9 EKG13324.1 - 1.4 8.4 5.7 1.7 8.2 3.9 1.1 1 0 0 1 1 1 0 IncA protein DUF913 PF06025.7 EKG13324.1 - 2.1 6.9 5.1 2.6 6.7 3.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Daxx PF03344.10 EKG13324.1 - 2.2 6.6 26.2 2.6 6.4 18.2 1.0 1 0 0 1 1 1 0 Daxx Family CDC27 PF09507.5 EKG13324.1 - 2.6 7.1 19.8 3.1 6.8 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DDHD PF02862.12 EKG13324.1 - 3.1 7.5 6.3 3.6 7.3 4.4 1.2 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.3 EKG13324.1 - 3.9 5.9 10.8 4.5 5.7 7.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 EKG13324.1 - 4 5.9 7.9 4.2 5.8 5.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.7 EKG13324.1 - 7 6.4 19.3 8.9 6.1 13.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.11 EKG13325.1 - 4.2e-11 42.1 10.8 5.3e-11 41.8 7.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.19 EKG13326.1 - 8.6e-37 126.8 7.4 1.1e-36 126.5 5.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG13326.1 - 2.2e-09 37.6 0.2 5.7e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG13326.1 - 8.9e-06 25.5 1.2 0.0016 18.2 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EKG13326.1 - 0.00011 22.1 0.3 0.00033 20.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG13326.1 - 0.015 14.2 0.6 0.042 12.7 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EKG13326.1 - 0.025 13.6 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EKG13326.1 - 0.034 12.6 0.0 0.47 8.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EKG13326.1 - 0.036 13.9 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NARP1 PF12569.3 EKG13327.1 - 0.54 8.9 16.7 1 8.0 11.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.9 EKG13327.1 - 1.8 6.7 4.1 2.5 6.3 2.8 1.1 1 0 0 1 1 1 0 Cellulose synthase MRI PF15325.1 EKG13327.1 - 8.2 7.4 16.6 6.9 7.6 0.2 3.0 2 1 1 3 3 3 0 Modulator of retrovirus infection Abhydrolase_6 PF12697.2 EKG13328.1 - 8.3e-27 94.5 0.6 1.2e-26 93.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG13328.1 - 7e-19 68.3 0.0 2.3e-18 66.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG13328.1 - 2.3e-14 53.3 0.0 1.8e-13 50.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EKG13328.1 - 9e-06 24.9 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EKG13328.1 - 0.00042 19.8 0.1 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.2 EKG13328.1 - 0.0046 15.8 0.0 0.0082 15.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Ser_hydrolase PF06821.8 EKG13328.1 - 0.0051 16.4 0.0 0.049 13.2 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_3 PF07859.8 EKG13328.1 - 0.006 16.1 0.0 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EKG13328.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 EKG13328.1 - 0.047 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ndr PF03096.9 EKG13328.1 - 0.058 11.8 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 Ndr family Abhydrolase_2 PF02230.11 EKG13328.1 - 0.059 12.8 0.0 4.9 6.5 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EKG13328.1 - 0.066 12.6 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EKG13328.1 - 0.12 12.2 0.1 0.53 10.1 0.0 2.1 3 0 0 3 3 3 0 Putative lysophospholipase Chlorophyllase PF07224.6 EKG13328.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase RPAP1_N PF08621.5 EKG13328.1 - 0.18 11.3 0.7 0.33 10.5 0.5 1.4 1 0 0 1 1 1 0 RPAP1-like, N-terminal Thioesterase PF00975.15 EKG13328.1 - 0.23 11.6 1.0 2.8 8.0 0.5 2.7 2 1 0 2 2 2 0 Thioesterase domain Kelch_5 PF13854.1 EKG13329.1 - 2.9e-10 39.8 2.9 3.3e-06 26.9 0.0 4.1 4 0 0 4 4 4 2 Kelch motif IncA PF04156.9 EKG13329.1 - 0.054 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 EKG13329.1 - 0.11 10.7 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_6 PF13964.1 EKG13329.1 - 0.17 12.1 8.3 14 6.0 0.1 4.9 4 1 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 EKG13329.1 - 0.74 9.4 7.6 11 5.6 0.0 4.0 3 0 0 3 3 3 0 Kelch motif Spore_YabQ PF09578.5 EKG13331.1 - 0.016 15.1 3.4 0.016 15.1 2.3 1.9 2 1 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) DUF1656 PF07869.7 EKG13331.1 - 1.9 8.3 9.6 7 6.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) MMR_HSR1 PF01926.18 EKG13332.1 - 3.5e-18 65.6 0.0 5.4e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG13332.1 - 5.4e-07 29.2 0.0 1.1e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EKG13332.1 - 0.00017 20.9 0.0 0.028 13.7 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 EKG13332.1 - 0.00025 20.9 0.1 0.02 14.7 0.2 2.3 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 EKG13332.1 - 0.00059 19.0 0.1 0.0013 17.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKG13332.1 - 0.026 14.8 0.2 0.064 13.5 0.1 1.7 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 EKG13332.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Complex1_LYR_2 PF13233.1 EKG13333.1 - 5.5e-19 68.5 0.1 6.6e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF812 PF05667.6 EKG13333.1 - 0.069 11.6 0.8 0.076 11.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Complex1_LYR PF05347.10 EKG13333.1 - 0.39 10.5 2.3 0.78 9.5 1.6 1.6 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EKG13333.1 - 0.86 9.8 4.0 2.7 8.2 2.8 1.9 1 1 0 1 1 1 0 Complex1_LYR-like FBPase PF00316.15 EKG13334.1 - 6e-125 416.3 0.0 6.9e-125 416.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EKG13334.1 - 0.09 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family RRM_1 PF00076.17 EKG13336.1 - 5.4e-82 269.4 5.9 1.8e-21 75.5 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG13336.1 - 3.7e-56 186.9 1.8 1.3e-14 53.8 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG13336.1 - 5.4e-40 135.0 0.7 1.5e-09 37.5 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EKG13336.1 - 8.9e-30 102.1 1.7 5.9e-29 99.5 0.3 2.8 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EKG13336.1 - 3e-05 23.6 0.0 10 5.9 0.0 4.8 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EKG13336.1 - 0.00025 21.2 0.1 3.3 8.0 0.0 3.7 3 0 0 3 3 3 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EKG13336.1 - 0.00078 19.1 3.0 0.67 9.7 0.1 3.8 3 0 0 3 3 3 2 Limkain b1 OB_RNB PF08206.6 EKG13336.1 - 0.016 14.7 0.7 9.2 5.8 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain Acetyltransf_7 PF13508.1 EKG13338.1 - 9.4e-12 44.9 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG13338.1 - 5.8e-10 39.0 0.0 9.1e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EKG13338.1 - 4.4e-09 36.2 0.0 4.1e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG13338.1 - 1.6e-07 31.4 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG13338.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKG13338.1 - 0.085 13.0 0.0 1.1 9.4 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG13338.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase p450 PF00067.17 EKG13339.1 - 1.3e-31 109.6 0.0 1.7e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_53 PF07745.8 EKG13340.1 - 6e-81 271.8 0.0 7.1e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 NAD_binding_1 PF00175.16 EKG13342.1 - 5e-09 36.7 0.0 7.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EKG13342.1 - 0.0069 16.2 0.0 0.25 11.2 0.0 2.1 1 1 0 2 2 2 1 Ferric reductase NAD binding domain SnoaL_2 PF12680.2 EKG13343.1 - 1.7e-05 25.1 0.2 2.5e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EKG13343.1 - 0.01 15.3 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase DUF2284 PF10050.4 EKG13343.1 - 0.063 12.8 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) zf-C2H2 PF00096.21 EKG13345.1 - 2.6e-22 77.7 24.6 2.8e-05 24.1 1.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG13345.1 - 4.3e-21 74.1 25.4 3.3e-07 30.2 0.7 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG13345.1 - 1.6e-15 56.2 23.7 0.0003 20.8 2.6 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG13345.1 - 1.7e-05 24.8 6.9 0.9 9.7 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG13345.1 - 0.0034 17.5 10.1 1.9 8.7 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EKG13345.1 - 0.023 14.5 17.0 1.6 8.7 0.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 EKG13345.1 - 0.096 12.3 0.3 0.096 12.3 0.2 3.4 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2HC_2 PF13913.1 EKG13345.1 - 0.16 11.6 7.4 6.4 6.5 0.2 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EKG13345.1 - 0.18 11.7 11.4 8.5 6.4 1.3 3.8 2 1 1 3 3 3 0 Zinc ribbon domain C1_1 PF00130.17 EKG13345.1 - 1.7 8.4 6.1 1.2 8.9 1.1 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ENTH PF01417.15 EKG13346.1 - 2.4e-48 163.1 0.1 3.9e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 ENTH domain DUF4264 PF14084.1 EKG13346.1 - 0.00041 19.6 0.2 0.00077 18.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4264) DUF1720 PF08226.6 EKG13346.1 - 0.00065 19.7 106.5 0.0015 18.5 14.3 5.1 2 1 2 4 4 4 1 Domain of unknown function (DUF1720) ANTH PF07651.11 EKG13346.1 - 0.0026 16.5 0.0 0.0043 15.8 0.0 1.3 1 0 0 1 1 1 1 ANTH domain UIM PF02809.15 EKG13346.1 - 0.0064 15.9 2.4 0.0064 15.9 1.7 2.8 2 0 0 2 2 2 1 Ubiquitin interaction motif RR_TM4-6 PF06459.7 EKG13346.1 - 0.16 11.8 6.5 0.35 10.7 4.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 EKG13346.1 - 0.63 9.3 6.8 4.9 6.4 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TPR_MLP1_2 PF07926.7 EKG13350.1 - 1.7e-31 108.7 28.8 1.7e-31 108.7 20.0 18.3 8 4 10 18 18 18 6 TPR/MLP1/MLP2-like protein WEMBL PF05701.6 EKG13350.1 - 0.00089 17.8 11.2 0.00089 17.8 7.8 11.5 4 2 8 12 12 12 2 Weak chloroplast movement under blue light DUF2353 PF09789.4 EKG13350.1 - 0.0025 17.1 2.9 0.0025 17.1 2.0 12.8 2 2 9 12 12 12 1 Uncharacterized coiled-coil protein (DUF2353) TFIIE_beta PF02186.10 EKG13351.1 - 1.8e-05 24.6 0.2 0.0027 17.6 0.0 2.5 2 0 0 2 2 2 2 TFIIE beta subunit core domain BTG PF07742.7 EKG13351.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 BTG family Polysacc_deac_1 PF01522.16 EKG13352.1 - 2.2e-14 53.1 0.0 4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Amidase PF01425.16 EKG13353.1 - 1.1e-29 103.6 0.0 1.2e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EKG13354.1 - 5.8e-38 130.4 17.3 9.9e-38 129.7 12.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG13354.1 - 1.2e-19 70.2 10.1 1.6e-19 69.8 7.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EKG13354.1 - 1.5e-15 56.4 7.3 1.8e-15 56.1 5.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EKG13354.1 - 6.1e-05 21.6 6.0 6.1e-05 21.6 4.2 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein ATG22 PF11700.3 EKG13354.1 - 0.00079 18.0 11.3 0.0011 17.5 7.9 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Claudin_2 PF13903.1 EKG13354.1 - 2.1 8.0 16.2 6.6 6.3 0.4 3.1 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Sulfatase PF00884.18 EKG13355.1 - 5.8e-73 245.7 0.0 6.8e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EKG13355.1 - 0.0014 17.1 0.0 0.002 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 EKG13355.1 - 0.011 15.9 3.3 0.17 12.1 0.5 2.8 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase tRNA-synt_2c PF01411.14 EKG13356.1 - 6.5e-08 31.3 0.0 8.5e-08 30.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EKG13356.1 - 4.4e-06 26.4 0.2 9.4e-06 25.4 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Oxidored_FMN PF00724.15 EKG13357.1 - 2.1e-53 181.5 0.0 2.2e-46 158.4 0.0 2.4 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Nuc_sug_transp PF04142.10 EKG13358.1 - 4.5e-85 284.6 6.4 5.6e-85 284.3 4.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EKG13358.1 - 3.3e-09 36.1 10.8 3.1e-07 29.6 2.9 2.0 2 0 0 2 2 2 2 UAA transporter family TPT PF03151.11 EKG13358.1 - 3.5e-06 26.7 23.9 1.6e-05 24.5 1.8 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EKG13358.1 - 5.4e-06 26.5 1.3 5.4e-06 26.5 0.9 2.7 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EKG13358.1 - 1.6e-05 24.9 3.3 1.6e-05 24.9 2.3 3.1 2 1 0 2 2 2 1 EamA-like transporter family UPF0546 PF10639.4 EKG13358.1 - 4.7 7.0 11.0 7.9 6.3 1.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 Sec63 PF02889.11 EKG13359.1 - 1.1e-44 152.9 0.7 1.6e-44 152.4 0.1 1.6 2 0 0 2 2 2 1 Sec63 Brl domain DEAD PF00270.24 EKG13359.1 - 8.6e-27 93.6 0.0 1.7e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG13359.1 - 3.6e-08 33.1 0.0 8.7e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG13359.1 - 2.4e-07 30.7 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EKG13359.1 - 0.0033 17.5 0.0 0.015 15.4 0.0 2.0 2 1 0 2 2 2 1 AAA domain HHH_5 PF14520.1 EKG13359.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain UvrD-helicase PF00580.16 EKG13359.1 - 0.045 13.0 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Cdd1 PF11731.3 EKG13359.1 - 0.086 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus V_ATPase_I PF01496.14 EKG13361.1 - 8.7e-295 979.4 0.1 9.9e-295 979.3 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EKG13361.1 - 0.0039 17.0 0.7 0.14 11.9 0.1 2.5 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus CheZ PF04344.8 EKG13361.1 - 0.019 14.6 3.9 0.062 12.9 0.1 2.3 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Filament PF00038.16 EKG13361.1 - 0.022 14.2 4.9 0.77 9.1 0.0 2.5 2 1 0 2 2 2 0 Intermediate filament protein THP2 PF09432.5 EKG13361.1 - 0.12 12.2 1.3 0.54 10.1 0.2 2.5 2 0 0 2 2 2 0 Tho complex subunit THP2 BLOC1_2 PF10046.4 EKG13361.1 - 0.12 12.4 3.2 0.13 12.3 0.3 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EKG13361.1 - 0.58 9.6 3.3 1 8.8 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator Cortex-I_coil PF09304.5 EKG13361.1 - 1.1 9.3 4.1 12 6.0 0.1 2.8 3 0 0 3 3 3 0 Cortexillin I, coiled coil Nup96 PF12110.3 EKG13362.1 - 1.7e-72 244.0 0.0 2.9e-72 243.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EKG13362.1 - 1.1e-46 158.2 0.0 1.9e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EKG13362.1 - 3.7e-20 72.2 161.3 2.5e-11 43.7 33.2 11.6 5 4 5 10 10 10 5 Nucleoporin FG repeat region Cactin_mid PF10312.4 EKG13362.1 - 0.046 12.9 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Conserved mid region of cactin EF-hand_1 PF00036.27 EKG13363.1 - 3.8e-22 75.8 7.3 3.9e-09 35.1 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 EKG13363.1 - 7.8e-21 73.9 3.3 3.2e-12 46.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EKG13363.1 - 2.4e-19 67.4 8.2 4.2e-08 32.4 0.2 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EKG13363.1 - 1.1e-17 63.3 9.4 1e-12 47.4 0.2 3.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EKG13363.1 - 9.1e-14 50.0 8.3 3.6e-06 26.0 0.1 3.7 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.2 EKG13363.1 - 1.1e-07 31.5 0.1 4.6e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EKG13363.1 - 5.5e-05 22.9 0.0 0.081 12.8 0.0 3.3 3 1 0 3 3 3 1 EF-hand domain Caleosin PF05042.8 EKG13363.1 - 0.14 11.7 0.0 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Caleosin related protein Complex1_51K PF01512.12 EKG13364.1 - 1.4e-47 161.2 0.0 2.2e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EKG13364.1 - 1.6e-18 65.5 0.4 1.6e-18 65.5 0.3 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EKG13364.1 - 7.7e-10 38.5 0.0 2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 SLBB domain PAP2 PF01569.16 EKG13367.1 - 5.5e-15 55.1 8.5 7.3e-15 54.7 5.1 1.8 1 1 0 1 1 1 1 PAP2 superfamily Hamartin PF04388.7 EKG13367.1 - 0.0034 16.1 0.7 0.0047 15.6 0.5 1.1 1 0 0 1 1 1 1 Hamartin protein Ras PF00071.17 EKG13368.1 - 5.1e-47 159.2 0.0 6.8e-47 158.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG13368.1 - 4.9e-10 39.9 0.0 7.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG13368.1 - 0.00015 21.0 0.0 0.0004 19.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG13368.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GDA1_CD39 PF01150.12 EKG13369.1 - 7.7e-105 350.8 0.0 9.9e-105 350.5 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family GATase PF00117.23 EKG13370.1 - 4.8e-13 48.9 0.0 6.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EKG13370.1 - 0.0058 16.2 0.0 0.0082 15.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EKG13370.1 - 0.014 14.8 0.3 0.22 10.9 0.2 2.6 1 1 0 1 1 1 0 Peptidase C26 MFS_1 PF07690.11 EKG13371.1 - 1.4e-23 83.1 21.9 2e-23 82.7 14.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.15 EKG13372.1 - 8.2e-62 208.2 1.2 8.2e-62 208.2 0.8 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG13372.1 - 1.2e-45 155.2 11.2 1.2e-45 155.2 7.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG13372.1 - 2.9e-29 103.0 0.0 2e-28 100.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG13372.1 - 4e-19 68.3 0.0 8.2e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EKG13372.1 - 1.1e-14 55.0 0.0 2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKG13372.1 - 1e-09 37.6 0.0 1.6e-08 33.8 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EKG13372.1 - 1.1e-06 28.4 0.1 2.5e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IPK PF03770.11 EKG13373.1 - 1.4e-29 103.1 0.0 1.5e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF3933 PF13069.1 EKG13373.1 - 0.13 11.9 1.8 0.3 10.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) Atrophin-1 PF03154.10 EKG13373.1 - 0.18 9.8 2.3 0.23 9.5 1.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Metallophos PF00149.23 EKG13374.1 - 4.3e-37 127.4 0.4 9e-30 103.5 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase NAD_binding_10 PF13460.1 EKG13375.1 - 3.1e-18 66.4 0.3 6.9e-18 65.3 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG13375.1 - 0.014 14.8 0.0 0.037 13.4 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M20 PF01546.23 EKG13375.1 - 0.084 12.3 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 K_trans PF02705.11 EKG13376.1 - 6e-185 615.6 12.4 7.1e-185 615.3 8.6 1.0 1 0 0 1 1 1 1 K+ potassium transporter Methyltransf_33 PF10017.4 EKG13377.1 - 3.7e-35 120.5 0.0 6.4e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EKG13377.1 - 6.7e-14 51.8 0.2 6.5e-11 42.0 0.1 2.4 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EKG13377.1 - 8.3e-10 39.1 0.8 4.8e-09 36.6 0.4 2.3 2 0 0 2 2 2 1 DinB superfamily Eno-Rase_FAD_bd PF07055.7 EKG13377.1 - 0.26 11.2 0.0 0.26 11.2 0.0 2.2 3 0 0 3 3 3 0 Enoyl reductase FAD binding domain Dicty_REP PF05086.7 EKG13378.1 - 1.2 6.7 0.7 2.1 6.0 0.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PI31_Prot_N PF11566.3 EKG13379.1 - 1.2e-31 109.3 0.0 1.5e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EKG13379.1 - 3.9e-14 53.0 15.9 3.9e-14 53.0 11.0 3.5 2 2 2 4 4 4 1 PI31 proteasome regulator zf-C2H2 PF00096.21 EKG13382.1 - 1.4e-06 28.3 9.4 0.0032 17.7 1.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG13382.1 - 5.9e-06 26.2 7.4 0.005 17.0 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG13382.1 - 0.00019 21.4 5.7 0.021 14.9 1.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG13382.1 - 0.069 13.3 4.1 1.2 9.4 1.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PRP21_like_P PF12230.3 EKG13382.1 - 0.074 12.5 0.5 0.11 12.0 0.4 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-H2C2_2 PF13465.1 EKG13382.1 - 0.22 11.9 10.6 0.49 10.7 3.6 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Ion_trans PF00520.26 EKG13383.1 - 1.7e-08 33.9 10.4 1.7e-08 33.9 7.2 2.3 2 1 0 2 2 2 1 Ion transport protein DUF1725 PF08333.6 EKG13384.1 - 0.07 12.4 0.4 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) CDC45 PF02724.9 EKG13384.1 - 1.1 7.2 4.9 1.4 6.8 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3112 PF11309.3 EKG13385.1 - 1.6e-44 151.4 22.2 2.9e-44 150.6 4.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) RNase_PH PF01138.16 EKG13387.1 - 7e-25 87.8 0.0 1.6e-24 86.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 EamA PF00892.15 EKG13388.1 - 0.00051 20.0 8.1 0.00051 20.0 5.6 1.4 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EKG13388.1 - 0.0068 16.5 5.4 0.013 15.7 3.7 1.4 1 0 0 1 1 1 1 Multidrug resistance efflux transporter Glyco_hydro_76 PF03663.9 EKG13389.1 - 1.4e-84 284.5 14.7 1.8e-84 284.2 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PC_rep PF01851.17 EKG13391.1 - 1.7e-20 72.0 15.2 6e-07 29.3 0.1 8.4 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EKG13391.1 - 6.5e-06 26.3 0.6 0.29 11.4 0.1 3.9 3 0 0 3 3 3 2 HEAT repeats DUF3574 PF12098.3 EKG13391.1 - 0.12 11.9 0.1 26 4.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) RIO1 PF01163.17 EKG13392.1 - 1.3e-43 148.6 0.2 4.2e-30 104.4 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EKG13392.1 - 4.8e-29 100.2 0.0 9.7e-29 99.2 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EKG13392.1 - 3.9e-08 33.3 0.1 0.0007 19.4 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EKG13392.1 - 3.4e-05 22.9 0.0 0.0024 16.9 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.7 EKG13392.1 - 6.3 5.9 7.1 9.2 5.4 4.9 1.1 1 0 0 1 1 1 0 NOA36 protein MatE PF01554.13 EKG13393.1 - 2.9e-55 186.2 28.2 9.1e-28 96.9 7.5 2.2 2 0 0 2 2 2 2 MatE GST_N_2 PF13409.1 EKG13394.1 - 4.2e-19 68.3 0.1 1.4e-18 66.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG13394.1 - 9.5e-17 60.6 0.0 1.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG13394.1 - 4.7e-06 26.4 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG13394.1 - 1.2e-05 25.4 0.1 0.00048 20.2 0.1 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG13394.1 - 5.1e-05 23.6 0.0 0.00012 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M43 PF05572.8 EKG13395.1 - 1.5e-16 60.3 0.0 2.6e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EKG13395.1 - 1.6e-05 25.0 0.1 2.1e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EKG13395.1 - 3.8e-05 24.2 0.1 8.3e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EKG13395.1 - 0.00013 22.0 0.1 0.00019 21.4 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EKG13395.1 - 0.00038 20.2 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EKG13395.1 - 0.0017 17.2 0.1 0.0025 16.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.1 EKG13395.1 - 0.0055 16.2 0.1 0.008 15.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like FAD_binding_3 PF01494.14 EKG13396.1 - 5.6e-22 78.2 0.1 1.8e-19 70.0 0.1 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG13396.1 - 0.00015 21.7 0.6 0.00015 21.7 0.4 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EKG13396.1 - 0.00085 18.0 0.0 0.019 13.6 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 EKG13396.1 - 0.002 17.0 6.2 0.0028 16.6 0.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG13396.1 - 0.038 12.8 3.9 0.068 11.9 1.0 2.1 2 0 0 2 2 2 0 FAD binding domain Spore_YtfJ PF09579.5 EKG13396.1 - 0.31 10.9 1.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) Methyltransf_23 PF13489.1 EKG13399.1 - 2.7e-22 79.2 0.0 5.8e-22 78.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG13399.1 - 1e-09 38.7 0.0 7e-09 36.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13399.1 - 1.2e-09 38.7 0.0 1.1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13399.1 - 2.6e-09 37.4 0.0 5.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13399.1 - 3.9e-08 33.0 0.0 2.8e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG13399.1 - 4.8e-05 23.6 0.0 0.0023 18.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EKG13399.1 - 0.00017 21.0 0.0 0.0068 15.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EKG13399.1 - 0.00017 21.6 0.0 0.0037 17.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EKG13399.1 - 0.00038 19.6 0.0 0.00062 18.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EKG13399.1 - 0.00093 18.3 0.0 0.0037 16.3 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EKG13399.1 - 0.0039 16.6 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EKG13399.1 - 0.017 14.2 0.0 1.5 7.8 0.0 2.5 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EKG13399.1 - 0.088 12.7 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase CMAS PF02353.15 EKG13399.1 - 0.11 11.5 0.0 0.27 10.2 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Aldedh PF00171.17 EKG13400.1 - 8.1e-131 436.5 0.0 9.1e-131 436.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EKG13400.1 - 1.2e-07 30.8 0.0 1.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Fungal_trans PF04082.13 EKG13401.1 - 3.6e-27 94.8 0.0 6.6e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2454 PF10521.4 EKG13402.1 - 1.1e-67 228.0 0.1 2.2e-67 227.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EKG13402.1 - 2.2e-23 82.8 0.3 6.9e-23 81.2 0.2 1.9 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EKG13402.1 - 0.0002 20.8 0.1 0.00074 19.0 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EKG13402.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 EKG13403.1 - 3.3e-117 391.6 1.4 5.7e-117 390.8 0.9 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Nop53 PF07767.6 EKG13404.1 - 1.2e-105 353.6 43.6 1.6e-105 353.3 30.2 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Adeno_hexon PF01065.14 EKG13404.1 - 5.6 5.6 6.6 8.6 5.0 4.6 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Ras PF00071.17 EKG13405.1 - 6.5e-42 142.6 0.0 8.1e-42 142.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EKG13405.1 - 1.6e-11 43.7 0.3 2e-11 43.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EKG13405.1 - 1.9e-10 41.2 0.1 4.3e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EKG13405.1 - 5.1e-06 26.0 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKG13405.1 - 0.016 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MAS20 PF02064.10 EKG13406.1 - 2.3e-19 69.4 0.8 6.9e-19 67.9 0.6 1.7 1 1 0 1 1 1 1 MAS20 protein import receptor CENP-X PF09415.5 EKG13406.1 - 0.0058 16.4 0.5 0.0093 15.7 0.4 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Vps51 PF08700.6 EKG13407.1 - 5.6e-17 61.3 1.6 5.6e-17 61.3 1.1 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EKG13407.1 - 0.0011 18.8 0.6 0.027 14.3 0.0 2.8 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.1 EKG13407.1 - 0.002 17.8 2.6 1.1 9.0 0.0 2.8 4 0 0 4 4 4 2 Exocyst complex component Sec5 DUF3608 PF12257.3 EKG13408.1 - 6.3e-74 248.3 0.0 1.1e-73 247.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EKG13408.1 - 1.1e-27 95.5 0.1 2.6e-27 94.3 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FNIP_N PF14636.1 EKG13409.1 - 1e-10 42.1 0.0 1e-10 42.1 0.0 5.3 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EKG13409.1 - 0.071 12.6 0.1 0.19 11.2 0.0 1.6 1 1 0 1 1 1 0 Folliculin-interacting protein middle domain adh_short PF00106.20 EKG13410.1 - 2.6e-26 92.5 1.5 4.5e-26 91.7 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG13410.1 - 2.2e-25 89.8 0.0 3.1e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG13410.1 - 2.4e-09 37.1 0.1 4e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 KR domain SepZ PF06066.6 EKG13410.1 - 0.58 10.1 6.4 0.57 10.2 1.0 2.7 2 1 0 2 2 2 0 SepZ F_bP_aldolase PF01116.15 EKG13411.1 - 1e-77 261.0 0.4 1.1e-77 260.9 0.3 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 EKG13411.1 - 0.026 13.5 0.1 0.05 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotriesterase family CobS PF02654.10 EKG13411.1 - 0.085 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-5-phosphate synthase Fungal_trans_2 PF11951.3 EKG13412.1 - 9.8e-10 37.5 0.3 1.3e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EKG13412.1 - 0.00042 19.2 0.5 0.0006 18.7 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBAN PF05874.6 EKG13412.1 - 0.048 13.0 0.3 0.087 12.1 0.2 1.4 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) Sugar_tr PF00083.19 EKG13413.1 - 1.1e-52 179.1 5.2 1.5e-52 178.6 3.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG13413.1 - 1.9e-22 79.5 9.0 2.4e-22 79.1 6.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG13413.1 - 0.003 16.0 9.5 0.061 11.7 0.7 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein bZIP_1 PF00170.16 EKG13415.1 - 0.18 11.7 7.1 0.4 10.6 4.9 1.6 1 1 0 1 1 1 0 bZIP transcription factor LcrG PF07216.7 EKG13415.1 - 0.31 11.1 1.9 1.6 8.8 1.3 2.0 2 0 0 2 2 2 0 LcrG protein NUDIX PF00293.23 EKG13416.1 - 3.1e-27 94.8 0.0 4.1e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain AAA_6 PF12774.2 EKG13416.1 - 0.032 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 F-box-like PF12937.2 EKG13417.1 - 6.4e-07 29.0 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG13417.1 - 1e-05 25.0 0.0 2.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 EKG13417.1 - 0.31 10.7 14.2 6.5 6.6 0.8 3.7 3 0 0 3 3 3 0 Ubiquitin interaction motif Aldo_ket_red PF00248.16 EKG13418.1 - 1.2e-69 234.2 0.0 1.6e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S74 PF13884.1 EKG13419.1 - 0.047 13.8 0.2 59 3.8 0.1 3.2 3 0 0 3 3 3 0 Chaperone of endosialidase SNARE PF05739.14 EKG13419.1 - 0.048 13.3 0.6 0.048 13.3 0.4 2.8 3 0 0 3 3 3 0 SNARE domain MutS_III PF05192.13 EKG13419.1 - 0.18 11.5 2.1 0.68 9.6 1.5 1.8 1 1 0 1 1 1 0 MutS domain III Mnd1 PF03962.10 EKG13419.1 - 0.28 10.8 5.3 1.4 8.5 1.9 2.1 2 0 0 2 2 2 0 Mnd1 family Baculo_PEP_C PF04513.7 EKG13419.1 - 0.32 10.8 5.2 3.3 7.5 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.8 EKG13419.1 - 1.4 8.8 6.3 22 4.9 2.7 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fib_alpha PF08702.5 EKG13419.1 - 2.5 8.1 5.5 5.6 7.0 1.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EKG13419.1 - 3.6 5.3 6.6 14 3.3 2.8 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family WXG100 PF06013.7 EKG13419.1 - 5.3 7.1 6.9 8.3 6.4 0.3 3.0 2 1 0 3 3 3 0 Proteins of 100 residues with WXG Fip1 PF05182.8 EKG13420.1 - 2.3e-20 71.5 0.8 4.5e-20 70.6 0.5 1.5 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.7 EKG13420.1 - 0.047 12.0 12.4 0.055 11.8 8.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2890 PF11081.3 EKG13420.1 - 0.14 12.1 7.9 0.26 11.3 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) FAM176 PF14851.1 EKG13420.1 - 1.9 8.1 6.5 3.1 7.4 4.5 1.3 1 0 0 1 1 1 0 FAM176 family Daxx PF03344.10 EKG13420.1 - 4.5 5.6 12.8 6.4 5.1 8.9 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EKG13420.1 - 7.6 4.3 16.4 9.5 3.9 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family TauD PF02668.11 EKG13421.1 - 1e-49 169.5 0.3 1.3e-49 169.1 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD-oxidase_C PF02913.14 EKG13424.1 - 1.6e-66 224.2 0.0 2e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EKG13424.1 - 2.5e-23 82.0 0.0 5e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Mur_ligase_M PF08245.7 EKG13425.1 - 6.7e-07 29.5 0.0 0.0027 17.7 0.0 3.0 3 1 0 3 3 3 2 Mur ligase middle domain Mannitol_dh PF01232.18 EKG13425.1 - 0.036 14.0 1.0 0.23 11.4 0.1 2.5 3 0 0 3 3 3 0 Mannitol dehydrogenase Rossmann domain Mur_ligase_C PF02875.16 EKG13425.1 - 0.06 13.3 0.2 0.23 11.5 0.0 2.2 2 1 0 2 2 2 0 Mur ligase family, glutamate ligase domain Aminotran_5 PF00266.14 EKG13426.1 - 7.4e-14 51.2 0.0 8.4e-14 51.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V TPK_catalytic PF04263.11 EKG13427.1 - 1.8e-19 69.5 0.0 7.4e-19 67.5 0.0 1.9 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EKG13427.1 - 1.7e-16 59.6 0.0 3.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain adh_short PF00106.20 EKG13429.1 - 1.5e-06 28.1 0.1 2.8e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase G-patch_2 PF12656.2 EKG13430.1 - 5.4e-28 96.6 0.1 5.4e-28 96.6 0.1 3.4 2 1 1 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 EKG13430.1 - 1.9e-06 27.5 1.4 1.9e-06 27.5 1.0 1.9 2 0 0 2 2 2 1 G-patch domain Flavokinase PF01687.12 EKG13431.1 - 3.7e-39 133.4 0.0 4.5e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase ACPS PF01648.15 EKG13433.1 - 6.2e-09 35.6 0.0 4.9e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Baculo_PEP_C PF04513.7 EKG13434.1 - 0.0093 15.7 10.3 0.017 14.9 7.1 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1180 PF06679.7 EKG13434.1 - 2.2 8.1 9.6 1.1 9.0 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Methyltransf_23 PF13489.1 EKG13436.1 - 2.2e-19 69.7 0.0 3.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13436.1 - 7.8e-11 42.3 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13436.1 - 7.4e-09 36.1 0.0 1.6e-07 31.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13436.1 - 7.4e-08 32.1 0.0 4.2e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG13436.1 - 2.1e-07 31.2 0.0 5.4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG13436.1 - 5.4e-06 26.7 0.0 3.8e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG13436.1 - 4e-05 22.8 0.0 0.00024 20.2 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EKG13436.1 - 0.00048 20.1 0.0 0.00094 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG13436.1 - 0.002 17.2 0.0 0.0085 15.1 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 EKG13436.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EKG13436.1 - 0.048 13.0 0.0 0.16 11.3 0.0 1.9 3 0 0 3 3 3 0 Methyltransferase small domain Abhydrolase_6 PF12697.2 EKG13438.1 - 1.9e-14 54.1 0.0 3.1e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13438.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG13438.1 - 0.039 13.8 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 Putative lysophospholipase RNase_H2_suC PF08615.6 EKG13440.1 - 3.1e-30 104.8 0.0 3.7e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.15 EKG13441.1 - 5.4e-70 235.5 0.0 3.8e-69 232.8 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EKG13441.1 - 2.5e-10 40.3 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13441.1 - 2.6e-09 37.6 0.0 5.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13441.1 - 1.9e-08 34.6 0.0 4.5e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13441.1 - 5e-08 32.6 0.0 7.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG13441.1 - 1e-05 25.5 0.1 5.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG13441.1 - 3.6e-05 24.1 0.0 7.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG13441.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EKG13441.1 - 0.0014 17.7 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 EKG13441.1 - 0.0027 17.2 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.1 EKG13441.1 - 0.004 17.9 0.0 0.24 12.2 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain DUF938 PF06080.7 EKG13441.1 - 0.024 14.1 0.0 0.07 12.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) MTS PF05175.9 EKG13441.1 - 0.04 13.3 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.11 EKG13441.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.15 EKG13441.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EKG13441.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase WHIM3 PF15614.1 EKG13442.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 RNase_T PF00929.19 EKG13444.1 - 1.3e-26 93.7 0.0 1.9e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EKG13444.1 - 0.00022 20.7 0.0 0.0008 18.9 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease MOZ_SAS PF01853.13 EKG13445.1 - 5.6e-88 293.1 0.1 1.1e-87 292.2 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EKG13445.1 - 2.1e-23 81.7 0.1 4.7e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF1918 PF08940.6 EKG13445.1 - 0.029 13.7 0.0 0.11 11.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Acetyltransf_1 PF00583.19 EKG13445.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family p450 PF00067.17 EKG13446.1 - 3.9e-47 160.8 0.0 4.8e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EKG13447.1 - 3.7e-16 58.7 5.3 4.7e-16 58.3 3.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 EKG13449.1 - 5.7e-95 318.5 17.3 6.5e-95 318.3 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG13449.1 - 7.9e-25 87.3 15.3 7.9e-25 87.3 10.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 EKG13450.1 - 1e-16 61.3 4.1 1.3e-16 60.9 0.8 2.5 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EKG13450.1 - 6.6e-09 35.6 0.3 1.2e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF2939 PF11159.3 EKG13450.1 - 0.044 13.9 0.3 0.56 10.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) NAD_binding_10 PF13460.1 EKG13450.1 - 0.063 13.2 0.9 0.16 11.9 0.6 1.8 2 1 0 2 2 2 0 NADH(P)-binding DUF3439 PF11921.3 EKG13451.1 - 2.4 7.9 16.1 0.058 13.1 6.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GST_N_3 PF13417.1 EKG13452.1 - 1.6e-14 53.8 0.0 3.3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG13452.1 - 6.2e-11 42.1 0.1 1.1e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EKG13452.1 - 8.2e-05 22.5 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.15 EKG13452.1 - 0.0007 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DFP PF04127.10 EKG13453.1 - 8.2e-14 51.6 0.0 0.00012 21.8 0.0 3.2 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Muted PF14942.1 EKG13453.1 - 0.093 12.6 1.1 0.44 10.4 0.2 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Fungal_trans PF04082.13 EKG13454.1 - 5.3e-16 58.2 0.0 1.8e-15 56.5 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG13454.1 - 3.5e-07 30.0 15.5 7.2e-07 29.0 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 EKG13455.1 - 2.5e-18 66.6 0.5 3.3e-18 66.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Uds1 PF15456.1 EKG13456.1 - 1.3e-39 134.9 5.4 1.3e-39 134.9 3.8 6.4 6 2 1 7 7 7 2 Up-regulated During Septation Fib_alpha PF08702.5 EKG13456.1 - 0.002 18.2 2.9 0.002 18.2 2.0 6.5 6 3 3 9 9 9 2 Fibrinogen alpha/beta chain family DUF840 PF05801.6 EKG13456.1 - 0.12 12.4 0.2 0.91 9.6 0.1 2.2 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) Phosphodiest PF01663.17 EKG13456.1 - 0.13 11.5 3.4 1.9 7.7 0.1 2.8 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase PNRC PF15365.1 EKG13456.1 - 0.24 11.4 3.8 0.18 11.8 0.1 2.8 2 1 0 2 2 2 0 Proline-rich nuclear receptor coactivator Baculo_PEP_C PF04513.7 EKG13456.1 - 4.5 7.1 21.8 3.3 7.5 2.2 5.7 5 1 2 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Acetyltransf_2 PF00797.12 EKG13457.1 - 2.8e-42 144.9 0.0 3.5e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase MOZ_SAS PF01853.13 EKG13460.1 - 9.3e-80 266.3 0.1 1.3e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family DUF2582 PF10771.4 EKG13460.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2582) HTH_11 PF08279.7 EKG13460.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 HTH domain Velvet PF11754.3 EKG13462.1 - 5.1e-48 163.3 2.2 1.3e-46 158.8 1.5 2.3 1 1 0 1 1 1 1 Velvet factor p450 PF00067.17 EKG13463.1 - 4.8e-32 111.0 0.0 1.2e-31 109.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EKG13464.1 - 1.2e-65 221.4 2.5 1.5e-65 221.1 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 F-box-like PF12937.2 EKG13465.1 - 2.2e-05 24.0 0.2 5.9e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG13465.1 - 0.00032 20.2 0.0 0.00069 19.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EKG13465.1 - 0.015 15.1 0.5 1 9.3 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat NIR_SIR PF01077.17 EKG13466.1 - 1.9e-55 186.5 0.1 1.7e-46 157.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EKG13466.1 - 4e-33 112.8 0.0 8.6e-16 57.3 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EKG13466.1 - 5.4e-31 107.5 0.0 1.2e-30 106.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EKG13466.1 - 3.9e-11 42.9 0.1 1.1e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_NdrI PF07972.6 EKG13466.1 - 0.015 15.2 0.0 0.073 12.9 0.0 2.2 2 0 0 2 2 2 0 NrdI Flavodoxin like Flavodoxin_3 PF12641.2 EKG13466.1 - 0.093 12.1 0.0 0.32 10.4 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain DHC_N1 PF08385.7 EKG13466.1 - 0.11 10.9 0.1 0.28 9.5 0.1 1.6 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 PAPS_reduct PF01507.14 EKG13467.1 - 1.7e-31 109.3 0.0 3.8e-20 72.4 0.0 3.0 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EKG13468.1 - 1.9e-21 75.4 0.0 8.3e-11 41.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG13468.1 - 2.5e-12 46.5 0.0 2.6e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG13468.1 - 0.016 15.0 0.1 0.73 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EKG13469.1 - 3.2e-63 213.1 0.0 4.6e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EKG13469.1 - 2.5e-34 118.3 2.6 2.8e-34 118.1 0.9 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EKG13469.1 - 1.3e-23 83.6 0.2 1.3e-22 80.4 0.0 2.6 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EKG13469.1 - 0.044 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain MOR2-PAG1_N PF14222.1 EKG13470.1 - 1.3e-215 717.2 0.0 2.2e-215 716.5 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EKG13470.1 - 1.2e-86 290.7 0.7 3.4e-86 289.2 0.5 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EKG13470.1 - 2.5e-34 118.1 8.0 9.2e-13 46.7 0.2 3.8 1 1 2 3 3 3 3 Cell morphogenesis central region HEAT PF02985.17 EKG13470.1 - 0.017 15.1 2.4 3.4 7.9 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.1 EKG13470.1 - 0.18 12.1 0.1 0.18 12.1 0.0 4.1 6 0 0 6 6 6 0 HEAT repeats COPI_assoc PF08507.5 EKG13471.1 - 1.1e-39 135.2 5.4 1.2e-39 135.1 3.7 1.0 1 0 0 1 1 1 1 COPI associated protein YtpI PF14007.1 EKG13471.1 - 2.9 7.8 15.4 0.39 10.6 4.0 2.2 2 0 0 2 2 2 0 YtpI-like protein ExoD PF06055.7 EKG13471.1 - 4.3 6.4 7.0 4.2 6.4 2.1 2.0 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Glyco_transf_5 PF08323.6 EKG13472.1 - 1.4e-15 57.4 0.0 2.4e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EKG13472.1 - 1.2e-05 24.7 0.0 2.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EKG13472.1 - 0.0054 16.8 3.5 0.0059 16.7 0.7 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain DUF808 PF05661.7 EKG13473.1 - 0.56 8.9 2.8 11 4.7 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF808) PhoD PF09423.5 EKG13474.1 - 2.1e-10 39.7 0.1 4.6e-07 28.7 0.1 2.3 2 1 0 2 2 2 2 PhoD-like phosphatase Fijivirus_P9-2 PF06837.6 EKG13475.1 - 0.13 11.3 0.4 0.27 10.3 0.2 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein Epimerase PF01370.16 EKG13476.1 - 2.1e-45 154.9 0.0 2.8e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EKG13476.1 - 3.4e-26 90.9 0.2 7.5e-26 89.8 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EKG13476.1 - 1.8e-17 62.9 0.0 7e-17 61.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EKG13476.1 - 3.5e-14 52.3 0.0 1.8e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EKG13476.1 - 9e-13 47.7 0.0 1.5e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EKG13476.1 - 7.4e-11 42.2 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EKG13476.1 - 1.6e-08 33.7 0.0 3.3e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EKG13476.1 - 2.6e-08 34.1 0.0 5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG13476.1 - 4.6e-07 29.6 0.0 8.8e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 EKG13476.1 - 0.0005 20.6 0.0 0.5 10.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain NmrA PF05368.8 EKG13476.1 - 0.00099 18.4 0.0 0.0064 15.7 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family DAO PF01266.19 EKG13476.1 - 0.0092 14.9 0.2 0.026 13.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EKG13476.1 - 0.018 14.3 0.1 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain tRNA_bind PF01588.15 EKG13477.1 - 3.7e-23 81.1 0.2 4.1e-22 77.8 0.2 2.4 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EKG13477.1 - 3.2e-08 33.9 0.0 8.6e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG13477.1 - 0.0018 18.2 1.2 0.0059 16.5 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG13477.1 - 0.0046 16.8 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4569 PF15133.1 EKG13477.1 - 0.015 14.7 1.5 0.03 13.7 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Kin17_mid PF10357.4 EKG13477.1 - 0.44 10.2 1.7 0.59 9.7 0.2 1.9 1 1 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein NPR3 PF03666.8 EKG13477.1 - 0.71 8.3 4.0 0.5 8.8 1.6 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Med3 PF11593.3 EKG13477.1 - 1.5 7.9 5.2 2.2 7.4 3.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NARP1 PF12569.3 EKG13477.1 - 3.2 6.3 10.2 6.8 5.3 7.1 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 EKG13477.1 - 7.4 6.3 10.0 13 5.5 6.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ETC_C1_NDUFA4 PF04800.7 EKG13478.1 - 1.3e-36 124.5 0.5 1.9e-36 123.9 0.4 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 EKG13479.1 - 3.3e-40 136.2 0.3 3.7e-40 136.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EKG13479.1 - 0.012 15.5 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f DUF1438 PF07270.6 EKG13485.1 - 0.053 13.3 0.3 0.053 13.3 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1438) adh_short PF00106.20 EKG13489.1 - 4.2e-32 111.3 0.0 6.1e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13489.1 - 2.7e-12 46.7 0.0 4.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EKG13489.1 - 0.01 15.5 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EKG13489.1 - 0.22 10.6 1.2 1.8 7.6 0.0 2.8 3 1 1 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MoCF_biosynth PF00994.19 EKG13491.1 - 2.5e-55 185.8 0.2 5.2e-29 100.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EKG13491.1 - 4.7e-37 126.8 1.9 7e-37 126.2 1.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EKG13491.1 - 3.5e-14 52.5 0.1 9.5e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) CTP_synth_N PF06418.9 EKG13491.1 - 0.00057 19.0 0.0 0.0009 18.4 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus BAF1_ABF1 PF04684.8 EKG13491.1 - 7.4 5.3 8.7 11 4.7 6.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ATP-synt_C PF00137.16 EKG13492.1 - 1.9e-25 88.5 24.6 2.9e-16 59.0 6.1 2.7 3 0 0 3 3 3 2 ATP synthase subunit C DUF3120 PF11318.3 EKG13492.1 - 0.016 15.4 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Lysis_S PF04971.7 EKG13492.1 - 0.22 11.2 0.1 0.22 11.2 0.0 2.5 3 0 0 3 3 3 0 Lysis protein S TFIIA_gamma_C PF02751.9 EKG13493.1 - 6.5e-26 89.9 1.0 9e-26 89.4 0.7 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EKG13493.1 - 1.2e-21 76.0 0.5 1.7e-21 75.4 0.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Plant_NMP1 PF06694.6 EKG13493.1 - 0.072 12.0 0.1 0.084 11.7 0.1 1.0 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Peptidase_C12 PF01088.16 EKG13494.1 - 1.4e-62 210.6 0.0 1.6e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Git3 PF11710.3 EKG13495.1 - 2.7e-31 108.7 13.1 4.1e-31 108.1 6.0 2.6 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EKG13495.1 - 7.1e-22 76.9 3.3 1.7e-21 75.7 2.3 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term ASXH PF13919.1 EKG13495.1 - 0.17 11.6 0.8 1.4 8.7 0.5 2.1 2 0 0 2 2 2 0 Asx homology domain Ribosom_S12_S23 PF00164.20 EKG13496.1 - 5.4e-42 142.0 1.2 6.9e-42 141.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IF-2B PF01008.12 EKG13497.1 - 3.6e-55 186.9 0.0 8.5e-55 185.7 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EKG13497.1 - 0.065 12.8 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 DeoR C terminal sensor domain GATA PF00320.22 EKG13498.1 - 1.9e-28 97.4 24.8 3.5e-16 58.2 2.2 2.8 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EKG13498.1 - 0.00015 21.0 4.6 0.0089 15.3 0.2 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 EKG13498.1 - 0.0012 18.6 0.5 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf RRN7 PF11781.3 EKG13498.1 - 0.0061 16.0 0.5 0.0061 16.0 0.3 2.9 2 1 1 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EKG13498.1 - 0.065 13.2 2.1 8.8 6.3 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EKG13498.1 - 0.085 12.0 6.9 0.2 10.9 0.7 2.9 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 EKG13498.1 - 0.81 9.4 3.9 1.5 8.6 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C2H2_3 PF13878.1 EKG13498.1 - 2.9 7.5 8.1 5.5 6.6 0.1 3.7 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO eIF-5_eIF-2B PF01873.12 EKG13498.1 - 2.9 7.5 4.7 10 5.8 0.2 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.6 EKG13498.1 - 5.3 6.7 12.6 0.15 11.7 0.3 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DUF775 PF05603.7 EKG13500.1 - 3.3e-61 206.3 0.0 4.3e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EKG13501.1 - 1.7e-10 40.6 0.2 3.7e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 EKG13502.1 - 1.4e-38 132.2 0.1 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EKG13503.1 - 6.2e-114 380.6 0.0 7e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein DUF3934 PF13070.1 EKG13504.1 - 0.061 13.5 0.2 0.086 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) tRNA_int_endo PF01974.12 EKG13505.1 - 5e-13 48.6 0.0 9.7e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Cu-oxidase_2 PF07731.9 EKG13507.1 - 3.1e-43 146.5 4.9 3e-41 140.1 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG13507.1 - 1e-40 138.1 5.8 2e-39 133.9 0.5 3.5 3 1 1 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG13507.1 - 2.8e-32 111.8 0.0 9.4e-32 110.1 0.0 2.0 1 0 0 1 1 1 1 Multicopper oxidase DHBP_synthase PF00926.14 EKG13509.1 - 1.1e-71 240.0 0.0 2.2e-71 239.1 0.0 1.4 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Pro-kuma_activ PF09286.6 EKG13511.1 - 1.1e-50 171.3 0.9 3.4e-50 169.7 0.2 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EKG13511.1 - 4.7e-06 25.9 0.6 8.6e-06 25.0 0.4 1.3 1 0 0 1 1 1 1 Subtilase family MCM PF00493.18 EKG13512.1 - 4.8e-135 449.6 0.4 7.7e-135 448.9 0.3 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKG13512.1 - 1.2e-23 83.9 0.0 4.8e-23 81.9 0.0 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKG13512.1 - 2.5e-08 33.3 0.0 1.1e-06 28.0 0.0 2.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EKG13512.1 - 0.0012 18.3 0.0 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EKG13512.1 - 0.0027 17.3 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG13512.1 - 0.0093 15.6 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2360 PF10152.4 EKG13512.1 - 0.19 11.9 8.4 0.058 13.6 0.4 3.4 4 0 0 4 4 4 0 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_5 PF12695.2 EKG13513.1 - 9.6e-08 31.9 0.0 1.6e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG13513.1 - 2.8e-06 27.4 3.0 5.8e-06 26.3 2.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EKG13513.1 - 0.00032 19.6 0.0 0.0014 17.5 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.8 EKG13513.1 - 0.0051 15.1 0.1 1.2 7.3 0.0 2.5 3 0 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II BCIP PF13862.1 EKG13514.1 - 5.3e-73 244.6 0.3 6.4e-73 244.4 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein GATase PF00117.23 EKG13515.1 - 5.6e-38 130.3 0.0 1.2e-37 129.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EKG13515.1 - 1.2e-37 127.5 0.0 2.5e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EKG13515.1 - 6.5e-11 41.5 0.2 6.9e-06 25.1 0.1 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EKG13515.1 - 2e-08 33.9 0.0 3.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EKG13515.1 - 0.00051 19.3 0.0 0.0038 16.5 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EKG13515.1 - 0.00068 19.2 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 EKG13515.1 - 0.0042 15.6 0.1 0.012 14.2 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase ThiI PF02568.9 EKG13515.1 - 0.0092 15.4 0.0 0.027 13.9 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 EKG13515.1 - 0.016 14.2 0.1 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.14 EKG13515.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MFS_1 PF07690.11 EKG13517.1 - 1.1e-23 83.4 7.3 1.3e-23 83.2 5.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 EKG13519.1 - 4.2e-70 236.5 0.0 5e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EKG13520.1 - 1.7e-06 27.6 0.5 5e-06 26.1 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EKG13520.1 - 0.006 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain DUF607 PF04678.8 EKG13521.1 - 7.3e-47 159.6 0.1 6.1e-46 156.5 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF607 WD40 PF00400.27 EKG13524.1 - 1.3e-80 262.6 20.2 1.5e-12 46.8 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EKG13524.1 - 1.2e-06 27.0 3.4 0.0004 18.6 0.6 4.5 3 2 2 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EKG13524.1 - 0.0003 19.6 0.1 0.22 10.2 0.1 3.8 1 1 1 2 2 2 1 Nup133 N terminal like bZIP_1 PF00170.16 EKG13524.1 - 0.17 11.8 0.4 0.31 11.0 0.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor HEAT PF02985.17 EKG13525.1 - 0.0072 16.3 2.4 6.5 7.1 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat IncA PF04156.9 EKG13525.1 - 0.0088 15.6 8.5 0.0088 15.6 5.9 2.0 2 0 0 2 2 2 1 IncA protein CAS_CSE1 PF03378.10 EKG13525.1 - 0.047 11.9 0.0 0.099 10.9 0.0 1.4 1 1 0 1 1 1 0 CAS/CSE protein, C-terminus MCRS_N PF13325.1 EKG13525.1 - 0.083 12.3 5.6 0.2 11.1 3.9 1.5 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein V_ATPase_I PF01496.14 EKG13525.1 - 0.16 9.8 1.4 0.25 9.1 1.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS-augmin3 PF14932.1 EKG13525.1 - 0.52 9.4 10.4 0.18 10.9 5.1 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.6 EKG13525.1 - 1 7.9 12.0 0.55 8.8 6.7 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.4 EKG13525.1 - 1.4 7.8 15.4 3 6.7 10.7 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBPIP PF07106.8 EKG13525.1 - 3 7.3 12.7 0.56 9.7 5.8 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CsbD PF05532.7 EKG13527.1 - 4e-11 42.4 26.4 5.5e-10 38.7 3.1 3.3 2 1 1 3 3 3 3 CsbD-like DJ-1_PfpI PF01965.19 EKG13529.1 - 3.1e-08 33.2 0.0 1.1e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EKG13529.1 - 4.3e-06 26.1 0.0 2.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family adh_short PF00106.20 EKG13529.1 - 0.042 13.7 1.0 0.08 12.8 0.7 1.4 1 0 0 1 1 1 0 short chain dehydrogenase FAM176 PF14851.1 EKG13530.1 - 0.2 11.3 5.2 0.31 10.7 3.6 1.3 1 0 0 1 1 1 0 FAM176 family Peptidase_S15 PF02129.13 EKG13531.1 - 1.1e-38 133.2 0.0 6.7e-38 130.6 0.0 2.2 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EKG13531.1 - 1.2e-23 84.2 0.1 4.3e-23 82.3 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain p450 PF00067.17 EKG13531.1 - 3.9e-21 75.1 0.0 1.5e-20 73.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Peptidase_S9 PF00326.16 EKG13531.1 - 0.042 13.0 0.3 0.14 11.3 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family GMC_oxred_N PF00732.14 EKG13532.1 - 5e-66 222.8 0.3 6.2e-66 222.5 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG13532.1 - 7.2e-06 25.1 1.5 0.001 18.0 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG13532.1 - 4.5e-05 22.4 1.1 0.047 12.5 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG13532.1 - 0.00013 21.9 0.1 0.00038 20.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG13532.1 - 0.00083 19.2 1.7 0.1 12.4 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG13532.1 - 0.0031 16.0 0.4 0.054 11.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EKG13532.1 - 0.0055 15.8 0.3 0.014 14.5 0.2 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EKG13532.1 - 0.0066 15.4 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EKG13532.1 - 0.01 16.2 1.0 0.039 14.3 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG13532.1 - 0.065 13.0 0.6 0.21 11.3 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG13532.1 - 0.076 13.0 0.6 1.5 8.7 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase peroxidase PF00141.18 EKG13533.1 - 7.9e-31 107.3 0.0 1.5e-30 106.3 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Glyco_hydro_18 PF00704.23 EKG13534.1 - 3.2e-37 128.7 0.0 2.8e-35 122.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EKG13534.1 - 9.1e-06 25.5 20.6 2.1e-05 24.3 14.3 1.6 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_66 PF13199.1 EKG13534.1 - 0.008 14.6 0.0 0.011 14.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 DPBB_1 PF03330.13 EKG13535.1 - 2.4e-07 30.6 0.0 2.4e-07 30.6 0.0 3.6 3 1 1 4 4 4 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel ADH_N PF08240.7 EKG13536.1 - 4.6e-25 87.4 1.7 1.1e-24 86.2 1.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG13536.1 - 1.5e-21 76.3 1.2 2.4e-21 75.6 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 EKG13536.1 - 0.07 12.8 0.1 0.49 10.1 0.0 2.3 1 1 1 2 2 2 0 HAD-hyrolase-like ParBc PF02195.13 EKG13539.1 - 1.9e-09 37.4 0.0 2.5e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Glyco_hydro_10 PF00331.15 EKG13541.1 - 1.6e-67 227.8 0.0 1.9e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 EKG13541.1 - 0.0023 17.1 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase COX7C PF02935.11 EKG13542.1 - 0.16 11.7 0.4 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc CitMHS PF03600.11 EKG13542.1 - 0.96 7.9 7.4 1.2 7.6 5.1 1.1 1 0 0 1 1 1 0 Citrate transporter TauD PF02668.11 EKG13544.1 - 2.8e-45 155.0 0.1 3.4e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_71 PF03659.9 EKG13545.1 - 4e-45 153.9 0.0 4.6e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 UbiA PF01040.13 EKG13546.1 - 1.8e-26 92.9 19.1 2.8e-26 92.2 13.2 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family TauD PF02668.11 EKG13547.1 - 7.7e-17 61.8 0.0 8.5e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ABM PF03992.11 EKG13548.1 - 0.00018 21.4 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase 3Beta_HSD PF01073.14 EKG13549.1 - 6.7e-05 21.7 0.0 0.00011 21.0 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKG13549.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG13549.1 - 0.00022 20.2 0.0 0.00027 19.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EKG13549.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DIOX_N PF14226.1 EKG13550.1 - 8.2e-17 61.7 0.0 1.4e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG13550.1 - 6.1e-14 52.1 0.0 1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.8 EKG13553.1 - 2.6e-38 131.5 0.0 3.1e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG13553.1 - 1.6e-12 47.7 0.2 1.8e-12 47.6 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EKG13553.1 - 3.6e-07 30.2 1.8 5.2e-07 29.7 1.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EKG13553.1 - 7.7e-07 28.7 0.2 9e-07 28.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKG13553.1 - 2.2e-06 27.4 0.6 3.8e-06 26.6 0.3 1.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EKG13553.1 - 2.8e-06 26.2 0.0 3.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EKG13553.1 - 3.6e-06 26.9 0.1 5e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EKG13553.1 - 0.027 13.3 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 EKG13553.1 - 0.029 14.6 0.1 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EKG13553.1 - 0.032 14.1 0.2 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EKG13553.1 - 0.079 11.8 0.5 0.11 11.4 0.4 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DXP_reductoisom PF02670.11 EKG13553.1 - 0.082 13.4 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase F420_oxidored PF03807.12 EKG13553.1 - 0.13 12.6 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent polyprenyl_synt PF00348.12 EKG13554.1 - 1.2e-60 204.5 0.0 1.4e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Methyltransf_2 PF00891.13 EKG13555.1 - 9.3e-28 97.0 0.0 1.6e-27 96.3 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EKG13555.1 - 0.039 13.3 0.0 0.095 12.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain adh_short PF00106.20 EKG13556.1 - 3.9e-18 65.9 4.4 6.6e-18 65.1 3.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG13556.1 - 7.4e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG13556.1 - 1.4e-06 28.1 0.5 1.8e-06 27.7 0.3 1.2 1 0 0 1 1 1 1 KR domain GPW_gp25 PF04965.9 EKG13556.1 - 0.13 11.7 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme Pyr_redox_3 PF13738.1 EKG13557.1 - 5.4e-25 88.6 0.0 1.3e-24 87.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG13557.1 - 2.2e-06 26.8 0.0 1.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EKG13557.1 - 5.8e-05 23.0 0.2 0.00016 21.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 EKG13557.1 - 0.0012 18.0 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EKG13557.1 - 0.015 15.4 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EKG13557.1 - 0.02 13.9 2.5 0.58 9.1 0.2 2.5 3 0 0 3 3 3 0 FAD binding domain IPPT PF01715.12 EKG13559.1 - 9.4e-56 188.6 0.1 1.9e-55 187.6 0.1 1.4 1 1 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 EKG13559.1 - 0.0029 17.6 0.3 0.0056 16.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG13559.1 - 0.11 12.7 0.3 0.24 11.6 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ABC_tran PF00005.22 EKG13560.1 - 1.3e-15 57.8 0.1 1.2e-14 54.7 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKG13560.1 - 4.1e-10 40.1 2.1 0.00051 20.0 0.3 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EKG13560.1 - 5.8e-05 22.3 0.0 0.2 10.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EKG13560.1 - 0.00011 21.5 0.0 0.054 12.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKG13560.1 - 0.00032 20.1 0.1 0.00068 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EKG13560.1 - 0.00056 17.3 0.1 0.00073 17.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.13 EKG13560.1 - 0.0011 18.4 0.0 0.0035 16.8 0.0 1.7 1 1 1 2 2 2 1 FtsK/SpoIIIE family PduV-EutP PF10662.4 EKG13560.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EKG13560.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EKG13560.1 - 0.0054 17.0 0.1 0.0093 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKG13560.1 - 0.021 14.9 0.0 0.12 12.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EKG13560.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EKG13560.1 - 0.026 14.5 0.2 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKG13560.1 - 0.036 14.8 0.1 0.069 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKG13560.1 - 0.041 13.0 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG13560.1 - 0.069 13.1 1.7 0.18 11.7 1.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EKG13560.1 - 0.091 12.4 0.4 0.7 9.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Phage_lambd_GpG PF06894.6 EKG13560.1 - 0.1 12.2 0.0 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) AAA_14 PF13173.1 EKG13560.1 - 0.1 12.5 0.0 0.84 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EKG13560.1 - 0.11 12.6 0.5 0.45 10.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain Arf PF00025.16 EKG13560.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family UPF0079 PF02367.12 EKG13560.1 - 0.13 11.8 0.0 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 EKG13560.1 - 0.2 10.1 0.0 0.27 9.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 EKG13562.1 - 2.2e-09 37.4 0.1 2.5e-09 37.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13562.1 - 2.5e-07 30.5 0.2 2.9e-07 30.3 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG13562.1 - 0.00032 20.5 0.1 0.00034 20.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3726 PF12525.3 EKG13562.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) Spermine_synth PF01564.12 EKG13563.1 - 1e-96 322.6 0.0 1.3e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EKG13563.1 - 0.00078 20.0 0.0 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG13563.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG13563.1 - 0.033 14.6 0.3 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain DUF43 PF01861.11 EKG13563.1 - 0.035 13.0 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_23 PF13489.1 EKG13563.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EKG13565.1 - 5.5e-12 45.9 1.4 6.4e-12 45.7 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13565.1 - 3.2e-07 30.2 0.8 3.5e-07 30.0 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG13565.1 - 0.0016 17.8 0.1 0.0018 17.7 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG13565.1 - 0.02 14.6 1.0 0.048 13.4 0.7 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Semialdhyde_dh PF01118.19 EKG13565.1 - 0.071 13.4 0.1 0.084 13.1 0.1 1.1 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KH_5 PF13184.1 EKG13565.1 - 0.079 12.7 0.1 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 NusA-like KH domain Tannase PF07519.6 EKG13566.1 - 3.3e-102 342.6 2.7 4.2e-102 342.3 1.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EKG13566.1 - 0.0013 18.5 0.5 0.018 14.7 0.2 2.3 1 1 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_8 PF13450.1 EKG13567.1 - 5.5e-16 58.3 0.1 7.4e-16 57.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EKG13567.1 - 4.7e-12 45.7 0.0 5.1e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EKG13567.1 - 7.9e-09 34.8 2.2 1e-08 34.4 1.5 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG13567.1 - 1.3e-07 30.8 0.1 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EKG13567.1 - 2.8e-07 29.9 0.3 2.8e-07 29.9 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG13567.1 - 1.8e-06 28.1 0.0 1.8e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG13567.1 - 5.2e-06 25.7 0.1 7.3e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EKG13567.1 - 1.4e-05 25.0 0.3 2e-05 24.5 0.2 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG13567.1 - 4.4e-05 22.7 0.5 5.2e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EKG13567.1 - 5.3e-05 21.8 0.3 7e-05 21.4 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EKG13567.1 - 0.0001 21.3 0.1 0.0001 21.3 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EKG13567.1 - 0.0006 18.8 0.2 0.00066 18.7 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EKG13567.1 - 0.0038 17.5 0.2 0.0055 17.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EKG13567.1 - 0.051 12.1 0.2 0.061 11.9 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.13 EKG13567.1 - 0.055 13.1 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EKG13568.1 - 1.3e-38 133.3 0.1 1.4e-38 133.1 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EKG13568.1 - 0.06 12.2 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_M43 PF05572.8 EKG13569.1 - 6.2e-12 45.3 0.0 1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A FA_desaturase PF00487.19 EKG13570.1 - 7.6e-41 140.2 16.9 1.1e-40 139.7 11.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3821 PF12863.2 EKG13570.1 - 0.094 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) Glyco_hydro_88 PF07470.8 EKG13573.1 - 6.4e-66 222.6 13.4 7.7e-66 222.4 9.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 NAD_kinase PF01513.16 EKG13574.1 - 3.9e-70 235.8 0.0 5.4e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF4583 PF15190.1 EKG13575.1 - 1.1 8.9 5.9 0.45 10.1 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4583) DUF3328 PF11807.3 EKG13576.1 - 3.2e-23 82.5 3.3 3.6e-13 49.6 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) Bac_rhamnosid PF05592.6 EKG13578.1 - 5e-27 94.3 0.3 1.2e-25 89.7 0.5 2.5 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EKG13578.1 - 0.00051 18.8 1.3 0.00078 18.2 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 EKG13578.1 - 0.013 14.1 1.4 1.4 7.5 0.1 2.1 1 1 1 2 2 2 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 EKG13578.1 - 0.026 13.1 0.6 0.038 12.6 0.4 1.1 1 0 0 1 1 1 0 Trehalase YkuD PF03734.9 EKG13578.1 - 0.068 13.4 0.6 1.9 8.7 0.0 2.5 2 1 0 2 2 2 0 L,D-transpeptidase catalytic domain Pyr_redox_3 PF13738.1 EKG13579.1 - 1.4e-20 74.2 0.0 3.9e-20 72.7 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG13579.1 - 2.7e-15 55.5 0.0 1.9e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG13579.1 - 1.9e-11 43.7 0.1 3.6e-10 39.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG13579.1 - 1.6e-09 37.9 0.0 9.4e-08 32.1 0.0 2.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG13579.1 - 3.8e-07 29.3 0.1 8.5e-05 21.6 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EKG13579.1 - 0.00012 22.4 0.0 0.16 12.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG13579.1 - 0.00074 19.3 0.2 0.37 10.5 0.1 4.0 4 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EKG13579.1 - 0.0014 17.5 0.4 0.01 14.7 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EKG13579.1 - 0.0016 17.6 0.1 0.35 9.9 0.0 2.8 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 EKG13579.1 - 0.003 17.7 0.0 0.41 10.9 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EKG13579.1 - 0.0076 15.1 0.0 0.017 13.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EKG13579.1 - 0.017 14.0 0.0 0.068 12.0 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EKG13579.1 - 0.031 13.1 0.0 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EKG13579.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG13579.1 - 0.11 10.9 0.1 0.29 9.5 0.0 1.7 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_2 PF03446.10 EKG13579.1 - 0.12 12.2 0.0 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 EKG13579.1 - 0.12 12.3 0.1 1.3 8.9 0.0 2.5 3 0 0 3 3 3 0 NADH(P)-binding Shikimate_DH PF01488.15 EKG13579.1 - 0.14 12.2 0.0 4.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EKG13579.1 - 0.16 11.4 0.2 23 4.4 0.0 3.2 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EKG13579.1 - 0.36 10.8 0.7 1.9e+02 2.0 0.0 3.8 4 0 0 4 4 4 0 TrkA-N domain Fungal_trans PF04082.13 EKG13580.1 - 1.8e-05 23.7 0.5 2.6e-05 23.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain QCR10 PF09796.4 EKG13580.1 - 0.0063 16.1 0.0 0.32 10.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pneumo_att_G PF05539.6 EKG13581.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF3604 PF12228.3 EKG13581.1 - 0.014 13.6 0.0 0.019 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) Cutinase PF01083.17 EKG13583.1 - 3.5e-49 166.9 5.2 4.7e-49 166.5 3.6 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EKG13583.1 - 0.0014 18.0 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF726 PF05277.7 EKG13583.1 - 0.02 13.7 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF726) Lipase_3 PF01764.20 EKG13583.1 - 0.031 13.8 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) VirJ PF06057.6 EKG13583.1 - 0.054 13.2 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 EKG13583.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CAP-ZIP_m PF15255.1 EKG13583.1 - 0.73 9.7 3.5 0.57 10.0 0.1 2.1 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region Pyr_redox_2 PF07992.9 EKG13584.1 - 1.2e-20 74.3 0.1 9.6e-20 71.3 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG13584.1 - 2e-07 31.2 0.0 0.00077 19.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG13584.1 - 2.8e-05 24.4 0.0 0.27 11.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG13584.1 - 0.00016 20.6 0.0 0.15 10.9 0.0 2.5 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EKG13584.1 - 0.00068 19.8 0.0 0.032 14.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EKG13584.1 - 0.0015 17.5 0.0 0.1 11.4 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG13584.1 - 0.0052 16.7 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EKG13584.1 - 0.042 13.8 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 EKG13584.1 - 0.043 13.5 0.1 13 5.5 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKG13584.1 - 0.06 12.3 0.4 5.7 5.8 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EKG13584.1 - 0.067 12.5 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2330 PF10092.4 EKG13584.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Sulfotransfer_3 PF13469.1 EKG13585.1 - 4.2e-05 24.5 1.4 7.3e-05 23.7 0.9 1.5 1 1 0 1 1 1 1 Sulfotransferase family ketoacyl-synt PF00109.21 EKG13586.1 - 5e-70 235.8 0.0 9.3e-70 234.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG13586.1 - 1.2e-36 125.1 0.9 7.5e-36 122.5 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EKG13586.1 - 1.5e-30 106.6 0.0 4.8e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EKG13586.1 - 2.2e-25 89.4 0.0 3.6e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EKG13586.1 - 5.4e-22 77.8 2.7 3.5e-10 39.9 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EKG13586.1 - 3e-13 50.0 0.0 1e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13586.1 - 1.4e-10 40.9 0.0 3.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG13586.1 - 1.2e-07 31.5 0.0 3.9e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG13586.1 - 4.5e-07 30.4 0.0 1.5e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EKG13586.1 - 1.9e-05 24.1 0.1 3.8e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EKG13586.1 - 2.5e-05 24.5 0.1 0.00011 22.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13586.1 - 2.8e-05 24.5 0.1 0.0002 21.7 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Thiolase_N PF00108.18 EKG13586.1 - 0.00021 20.3 0.0 0.00048 19.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_26 PF13659.1 EKG13586.1 - 0.00025 21.0 0.0 0.0011 18.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EKG13586.1 - 0.00029 20.2 0.1 0.0023 17.2 0.1 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain PCMT PF01135.14 EKG13586.1 - 0.0011 18.6 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EKG13586.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) DREV PF05219.7 EKG13586.1 - 0.027 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 EKG13586.1 - 0.051 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SRP_SPB PF02978.14 EKG13586.1 - 0.059 13.6 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 Signal peptide binding domain MFS_1 PF07690.11 EKG13587.1 - 1.1e-22 80.2 21.9 1.5e-22 79.8 15.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG13587.1 - 6.7e-11 41.0 11.3 8.5e-11 40.7 7.5 1.3 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG13587.1 - 1.5e-05 23.8 4.5 1.5e-05 23.8 3.1 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter DUF1228 PF06779.9 EKG13587.1 - 0.0028 17.6 1.0 0.018 15.0 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) DUF4231 PF14015.1 EKG13587.1 - 0.91 9.5 15.8 0.056 13.4 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) 2OG-FeII_Oxy PF03171.15 EKG13588.1 - 2.9e-10 40.3 0.0 4.9e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EKG13588.1 - 5.9e-07 30.0 0.0 9.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal CAP_N PF01213.14 EKG13588.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.5 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_4 PF01565.18 EKG13589.1 - 3.9e-24 84.6 2.2 1.6e-23 82.6 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EKG13589.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_97 PF10566.4 EKG13589.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 p450 PF00067.17 EKG13590.1 - 4.2e-58 197.0 0.0 5e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG13593.1 - 4.6e-20 72.1 4.2 1.8e-19 70.2 2.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13593.1 - 4.3e-11 42.7 0.5 3e-09 36.8 0.2 2.3 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EKG13593.1 - 1.2e-07 31.7 0.0 4.5e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EKG13593.1 - 1.8e-05 23.8 0.0 5.3e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EKG13593.1 - 0.012 15.2 1.9 0.032 13.8 0.8 2.0 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EKG13593.1 - 0.014 15.1 0.2 0.027 14.2 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG13593.1 - 0.16 11.4 0.4 0.49 9.7 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EKG13594.1 - 5.2e-26 91.8 0.7 6e-26 91.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG13594.1 - 5e-21 75.3 1.2 7.2e-21 74.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13594.1 - 3e-06 27.0 1.7 3.9e-06 26.6 1.2 1.1 1 0 0 1 1 1 1 KR domain Urease_beta PF00699.15 EKG13594.1 - 0.086 12.6 0.1 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Urease beta subunit DUF1776 PF08643.5 EKG13594.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) rpo30_N PF12410.3 EKG13595.1 - 0.051 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit ThuA PF06283.6 EKG13597.1 - 2.2e-44 151.7 3.0 4.4e-44 150.7 2.1 1.5 1 1 0 1 1 1 1 Trehalose utilisation PBP PF01161.15 EKG13599.1 - 0.012 15.5 0.8 0.021 14.6 0.5 1.3 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Glyco_hydro_71 PF03659.9 EKG13600.1 - 2.6e-24 85.4 0.4 2.6e-24 85.4 0.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 ABM PF03992.11 EKG13602.1 - 4.9e-06 26.4 0.5 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Sulfatase PF00884.18 EKG13603.1 - 4.4e-11 42.5 0.1 5.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Abhydro_lipase PF04083.11 EKG13603.1 - 0.14 11.5 0.0 0.49 9.7 0.1 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Polyketide_cyc2 PF10604.4 EKG13605.1 - 1.9e-10 41.0 0.0 2.2e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Peptidase_M76 PF09768.4 EKG13607.1 - 0.039 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase M76 family FlaC_arch PF05377.6 EKG13607.1 - 0.093 12.6 0.5 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2823 PF11034.3 EKG13611.1 - 0.037 14.1 3.6 31 4.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2823) DUF3328 PF11807.3 EKG13612.1 - 0.013 15.2 0.1 0.02 14.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EKG13614.1 - 1.3e-29 103.4 0.1 1.6e-29 103.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2275 PF10039.4 EKG13615.1 - 0.041 13.7 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) DUF3328 PF11807.3 EKG13615.1 - 0.71 9.5 6.4 28 4.3 2.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EKG13616.1 - 6.5e-22 77.7 27.2 1.2e-21 76.7 18.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG13616.1 - 3.8e-10 38.6 3.3 7e-10 37.7 2.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_1 PF00583.19 EKG13617.1 - 4.6e-08 32.9 0.1 7.4e-08 32.3 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG13617.1 - 2e-06 27.8 0.0 9.5e-06 25.6 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG13617.1 - 2.7e-06 27.2 0.1 1.8e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG13617.1 - 7.8e-05 22.7 0.0 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EKG13617.1 - 0.034 14.0 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG13617.1 - 0.039 13.8 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EKG13617.1 - 0.076 12.9 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain polyprenyl_synt PF00348.12 EKG13619.1 - 5.7e-36 123.7 0.0 7.5e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 EKG13622.1 - 3.7e-35 121.3 0.0 5e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 EKG13623.1 - 2.2e-44 152.0 0.1 2.5e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family COesterase PF00135.23 EKG13624.1 - 1.5e-52 179.0 0.0 2e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family CHAT PF12770.2 EKG13625.1 - 2e-35 122.3 0.2 9.2e-35 120.1 0.1 2.0 2 0 0 2 2 2 1 CHAT domain HET PF06985.6 EKG13628.1 - 4.1e-35 120.9 1.3 4.1e-35 120.9 0.9 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EKG13630.1 - 0.0018 18.4 1.9 0.004 17.3 1.3 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pecanex_C PF05041.10 EKG13631.1 - 0.091 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Pecanex protein (C-terminus) DUF900 PF05990.7 EKG13635.1 - 3.9e-05 23.1 0.0 0.00011 21.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EKG13635.1 - 0.0001 21.9 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EKG13635.1 - 0.00042 19.8 0.0 0.00085 18.8 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain LCAT PF02450.10 EKG13635.1 - 0.0066 15.4 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.8 EKG13635.1 - 0.054 13.0 2.7 0.25 10.9 0.0 2.6 2 0 0 2 2 2 0 Serine hydrolase AA_permease_2 PF13520.1 EKG13636.1 - 0.00028 19.5 1.5 0.00028 19.5 1.1 1.3 2 0 0 2 2 2 1 Amino acid permease DUF3509 PF12021.3 EKG13637.1 - 0.068 12.9 0.4 0.2 11.4 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) Peptidase_M13_N PF05649.8 EKG13638.1 - 4.6e-90 302.4 0.0 5.9e-90 302.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EKG13638.1 - 6.8e-57 191.9 0.0 1.9e-56 190.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M13 Aldo_ket_red PF00248.16 EKG13639.1 - 6.4e-74 248.3 0.0 7.3e-74 248.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EKG13640.1 - 3.2e-09 35.8 0.0 3.9e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG13641.1 - 3e-41 141.4 0.0 9.8e-26 90.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EKG13642.1 - 2.3e-50 171.4 0.0 3.1e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_4 PF13439.1 EKG13642.1 - 0.064 12.9 0.1 0.17 11.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Abhydrolase_1 PF00561.15 EKG13643.1 - 4.4e-18 65.6 0.1 6.1e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG13643.1 - 1.6e-08 34.7 4.3 2.2e-08 34.2 3.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13643.1 - 0.012 15.3 0.8 0.019 14.7 0.6 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EKG13643.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase ATP-grasp_4 PF13535.1 EKG13644.1 - 1.1e-23 83.8 0.0 2.1e-22 79.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EKG13644.1 - 6.4e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EKG13644.1 - 0.0004 20.2 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG13644.1 - 0.00058 18.7 0.0 0.017 13.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EKG13644.1 - 0.0016 17.8 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 EKG13644.1 - 0.0079 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EKG13644.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 EKG13644.1 - 0.058 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RimK PF08443.6 EKG13644.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain COesterase PF00135.23 EKG13645.1 - 2.3e-89 300.5 0.0 3.1e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG13645.1 - 6.2e-06 25.9 0.0 1.5e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold p450 PF00067.17 EKG13646.1 - 4.3e-25 88.1 0.0 5.4e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 EKG13647.1 - 5.8e-46 157.2 0.0 6.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG13647.1 - 4.3e-07 29.7 3.4 0.0013 18.3 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EKG13647.1 - 0.0065 15.1 0.0 1.8 7.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Pyr_redox_3 PF13738.1 EKG13649.1 - 2.9e-11 43.8 0.0 4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG13649.1 - 2.8e-10 40.0 0.0 4.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EKG13649.1 - 3.8e-08 31.9 0.1 5e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EKG13649.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.5 1 1 1 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EKG13649.1 - 0.0048 15.8 0.0 1.8 7.3 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EKG13649.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG13649.1 - 0.032 12.7 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EKG13649.1 - 0.047 12.6 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SF3a60_bindingd PF12108.3 EKG13649.1 - 0.065 12.7 0.7 0.13 11.7 0.5 1.5 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain PSRP-3_Ycf65 PF04839.8 EKG13649.1 - 1.1 9.3 5.1 4.3 7.4 0.3 3.0 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) Glyco_hydro_1 PF00232.13 EKG13650.1 - 4.4e-18 64.7 0.0 5.1e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 MFS_1 PF07690.11 EKG13651.1 - 1.7e-22 79.6 30.1 2.7e-21 75.6 18.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG13651.1 - 1.6e-06 27.0 12.7 1.6e-06 27.0 8.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Pyr_redox_3 PF13738.1 EKG13653.1 - 8.2e-26 91.3 0.0 1.3e-25 90.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG13653.1 - 1.4e-09 37.8 0.1 0.00098 18.9 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG13653.1 - 0.0001 22.2 0.0 0.0012 18.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG13653.1 - 0.00011 21.3 0.0 0.0072 15.2 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EKG13653.1 - 0.032 13.1 0.1 0.3 9.9 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG13653.1 - 0.18 10.2 0.3 6.8 5.0 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein PRTP PF01366.13 EKG13654.1 - 0.0038 15.2 0.0 0.0044 15.0 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus processing and transport protein Baculo_PEP_C PF04513.7 EKG13654.1 - 0.062 13.1 2.8 0.57 10.0 0.1 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spore_III_AB PF09548.5 EKG13654.1 - 0.072 12.8 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Snapin_Pallidin PF14712.1 EKG13654.1 - 0.19 12.0 1.4 0.3 11.4 1.0 1.4 1 0 0 1 1 1 0 Snapin/Pallidin His_Phos_2 PF00328.17 EKG13655.1 - 8e-42 143.8 0.0 9.8e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) E1-E2_ATPase PF00122.15 EKG13656.1 - 3.3e-37 127.7 7.5 3.3e-37 127.7 5.2 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EKG13656.1 - 1.4e-22 81.2 2.2 1e-20 75.0 1.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG13656.1 - 1.7e-10 41.3 0.0 4.3e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EKG13656.1 - 6.6e-10 38.9 0.8 1.5e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EKG13656.1 - 0.15 11.6 0.1 0.77 9.2 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EKG13657.1 - 5.5e-19 68.0 0.1 8e-19 67.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.23 EKG13661.1 - 2.7e-07 31.0 0.0 1.9e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.11 EKG13662.1 - 1e-29 103.4 43.5 1.3e-28 99.7 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3007 PF11460.3 EKG13662.1 - 2.2 8.3 5.2 0.4 10.7 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Dicty_CAR PF05462.6 EKG13664.1 - 7.4e-09 34.9 6.3 9.8e-09 34.5 4.4 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EKG13664.1 - 1.2e-08 34.8 9.3 1.8e-08 34.1 6.4 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EKG13664.1 - 2.7e-05 23.4 0.2 3.3e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Na_Ca_ex PF01699.19 EKG13664.1 - 0.64 9.6 7.4 0.14 11.7 1.8 2.2 2 1 0 2 2 2 0 Sodium/calcium exchanger protein SUR7 PF06687.7 EKG13664.1 - 1.2 8.6 7.3 1.7 8.1 3.0 2.1 1 1 1 2 2 2 0 SUR7/PalI family Glyco_hydro_16 PF00722.16 EKG13666.1 - 2.6e-20 72.5 3.3 4.5e-20 71.7 2.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DnaJ PF00226.26 EKG13667.1 - 2.5e-22 78.3 0.9 4.8e-22 77.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain NmrA PF05368.8 EKG13668.1 - 2.5e-22 79.2 0.0 5.3e-22 78.2 0.0 1.4 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EKG13668.1 - 4.1e-15 56.2 0.0 7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding GGDN PF05165.7 EKG13668.1 - 0.052 12.5 0.2 0.078 12.0 0.1 1.2 1 0 0 1 1 1 0 GGDN family NAD_binding_7 PF13241.1 EKG13668.1 - 0.056 13.7 0.1 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding RmlD_sub_bind PF04321.12 EKG13668.1 - 0.056 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 EKG13668.1 - 0.087 12.2 0.0 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Malate_synthase PF01274.17 EKG13669.1 - 2.4e-230 764.9 0.0 2.8e-230 764.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Asp PF00026.18 EKG13670.1 - 2.2e-14 53.4 0.6 3.3e-14 52.8 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EKG13670.1 - 0.0005 19.3 2.9 0.00094 18.4 2.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RCR PF12273.3 EKG13670.1 - 0.0085 16.6 1.6 0.01 16.3 0.2 1.8 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red VSP PF03302.8 EKG13670.1 - 0.0095 14.6 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 1 Giardia variant-specific surface protein EphA2_TM PF14575.1 EKG13670.1 - 0.087 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MmgE_PrpD PF03972.9 EKG13674.1 - 2.1e-147 490.9 0.0 2.4e-147 490.7 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Fungal_trans_2 PF11951.3 EKG13675.1 - 1.4e-58 198.3 0.2 1.9e-58 197.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain EutQ PF06249.7 EKG13676.1 - 1.1e-09 38.0 0.0 1.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EKG13676.1 - 9.4e-08 31.3 0.0 1.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EKG13676.1 - 0.0047 16.3 0.1 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EKG13676.1 - 0.038 13.6 0.0 0.041 13.5 0.0 1.1 1 0 0 1 1 1 0 Cupin PTCB-BRCT PF12738.2 EKG13677.1 - 2.6e-14 52.8 0.0 4.8e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EKG13677.1 - 3.6e-08 33.4 0.0 5.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF1297 PF06973.7 EKG13677.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1297) PAT1 PF09770.4 EKG13677.1 - 0.77 7.9 9.6 0.8 7.8 6.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 vATP-synt_E PF01991.13 EKG13678.1 - 2e-66 223.0 11.2 2.3e-66 222.8 7.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Prenyltransf PF01255.14 EKG13678.1 - 0.095 11.8 2.1 0.15 11.1 1.0 1.5 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Methyltransf_7 PF03492.10 EKG13678.1 - 0.21 10.2 2.2 0.3 9.7 1.6 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DUF2263 PF10021.4 EKG13678.1 - 0.6 10.0 3.2 2 8.3 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) DUF1910 PF08928.5 EKG13678.1 - 1.6 8.7 4.4 0.28 11.2 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) DUF2462 PF09495.5 EKG13678.1 - 7 7.4 10.0 2.9 8.6 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Mg_trans_NIPA PF05653.9 EKG13679.1 - 1.7e-18 66.6 5.4 2.3e-18 66.1 3.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EKG13679.1 - 0.00031 20.7 1.2 0.00031 20.7 0.8 3.2 2 1 1 3 3 3 2 EamA-like transporter family DUF4653 PF15546.1 EKG13679.1 - 0.12 11.6 0.1 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF2207 PF09972.4 EKG13679.1 - 1.4 7.4 6.6 0.81 8.2 0.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3040 PF11239.3 EKG13679.1 - 2 8.5 5.4 2.8 8.0 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Mpv17_PMP22 PF04117.7 EKG13681.1 - 3.6e-19 68.1 1.1 9e-19 66.8 0.0 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Claudin_2 PF13903.1 EKG13682.1 - 0.083 12.5 1.9 0.17 11.6 1.3 1.6 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction B12D PF06522.6 EKG13682.1 - 0.093 12.4 0.1 11 5.8 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3720 PF12517.3 EKG13684.1 - 3.4 8.4 6.8 8.9 7.0 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3720) AMP-binding PF00501.23 EKG13685.1 - 2.9e-71 240.0 0.0 3.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG13685.1 - 6.2e-09 36.6 0.2 4.4e-08 33.9 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ndr PF03096.9 EKG13686.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Zn_clus PF00172.13 EKG13687.1 - 3e-08 33.4 7.9 4.8e-08 32.7 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EKG13687.1 - 7.2e-08 31.6 0.8 7.2e-08 31.6 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG13688.1 - 2.7e-38 131.6 25.6 6.8e-38 130.2 17.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 EKG13689.1 - 3.4e-23 82.4 8.5 5.8e-22 78.3 1.6 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EKG13689.1 - 1.7e-18 67.2 1.4 5.2e-10 39.5 0.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG13689.1 - 3.2e-11 43.2 0.4 7.1e-11 42.1 0.3 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG13689.1 - 0.0001 21.8 0.2 0.00021 20.7 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG13689.1 - 0.00013 20.9 0.0 0.00023 20.1 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EKG13689.1 - 0.00016 20.6 0.1 0.00056 18.8 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Shikimate_DH PF01488.15 EKG13689.1 - 0.0023 18.0 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EKG13689.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EKG13689.1 - 0.0056 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Urocanase PF01175.13 EKG13689.1 - 0.0089 14.1 0.3 0.024 12.7 0.0 1.7 2 0 0 2 2 2 1 Urocanase 3Beta_HSD PF01073.14 EKG13689.1 - 0.022 13.4 0.1 0.032 12.9 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG13689.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein DUF2730 PF10805.3 EKG13689.1 - 0.054 13.2 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) NAD_binding_10 PF13460.1 EKG13689.1 - 0.068 13.1 1.0 0.14 12.1 0.7 1.9 1 1 0 1 1 1 0 NADH(P)-binding Methyltransf_25 PF13649.1 EKG13689.1 - 0.085 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_3 PF03447.11 EKG13689.1 - 0.089 13.1 0.5 0.31 11.4 0.1 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Mto2_bdg PF12808.2 EKG13690.1 - 0.014 15.4 1.0 0.014 15.4 0.7 1.9 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3987 PF13148.1 EKG13690.1 - 0.026 13.1 1.1 0.03 12.9 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AF0941-like PF14591.1 EKG13690.1 - 0.03 14.3 0.4 0.034 14.2 0.3 1.1 1 0 0 1 1 1 0 AF0941-like BACK PF07707.10 EKG13691.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 BTB And C-terminal Kelch Peptidase_S10 PF00450.17 EKG13692.1 - 6.4e-60 203.4 4.3 8.7e-60 203.0 3.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3433 PF11915.3 EKG13694.1 - 4.5e-29 100.4 11.1 4.5e-19 68.3 0.2 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF4401 PF14351.1 EKG13694.1 - 2.9 6.8 13.8 0.041 12.8 3.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4401) Beta_helix PF13229.1 EKG13695.1 - 0.00038 20.2 31.3 0.004 16.9 14.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region Piwi PF02171.12 EKG13696.1 - 1.1e-67 228.1 0.0 5e-67 226.0 0.0 1.8 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EKG13696.1 - 8.2e-15 53.9 0.1 1.8e-14 52.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EKG13696.1 - 7e-11 41.5 0.0 4.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 PAZ domain FAD_binding_2 PF00890.19 EKG13697.1 - 1.1e-51 175.9 1.0 1.4e-51 175.6 0.7 1.0 1 0 0 1 1 1 1 FAD binding domain Amidase PF01425.16 EKG13698.1 - 1.4e-96 324.0 0.1 1.6e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 Amidase ADH_N PF08240.7 EKG13699.1 - 1.6e-06 27.8 0.0 3.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG13699.1 - 0.0096 15.4 0.1 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 EKG13701.1 - 4e-22 78.4 75.4 4.5e-15 55.2 31.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 EKG13702.1 - 1.2e-177 590.5 0.1 2.3e-97 326.0 0.1 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EKG13702.1 - 8.7e-79 264.4 0.1 3.2e-31 108.3 0.0 3.6 3 1 1 4 4 4 3 Condensation domain PP-binding PF00550.20 EKG13702.1 - 4.2e-15 55.7 0.7 3.5e-06 27.1 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG13702.1 - 2.1e-13 50.9 0.5 1.7e-07 32.1 0.1 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain EBV-NA3 PF05009.7 EKG13702.1 - 0.063 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SoxZ PF08770.6 EKG13704.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ CHAT PF12770.2 EKG13705.1 - 1.4e-31 109.7 0.0 3.4e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 CHAT domain Thioredoxin_4 PF13462.1 EKG13705.1 - 0.049 13.6 0.4 0.13 12.2 0.3 1.7 1 0 0 1 1 1 0 Thioredoxin PGM_PMM_II PF02879.11 EKG13705.1 - 0.16 12.3 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II TPR_12 PF13424.1 EKG13705.1 - 0.5 10.3 10.7 1.2 9.1 0.3 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Ecm33 PF12454.3 EKG13706.1 - 0.0038 17.0 5.3 0.0038 17.0 3.7 2.6 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein Cytochrom_C_2 PF01322.15 EKG13706.1 - 0.24 11.9 6.9 0.048 14.1 1.8 2.0 2 0 0 2 2 2 0 Cytochrome C' Tyrosinase PF00264.15 EKG13707.1 - 8.6e-32 111.0 3.4 1.3e-31 110.4 2.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Glucosamine_iso PF01182.15 EKG13708.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase p450 PF00067.17 EKG13709.1 - 1.7e-16 59.8 0.0 2e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ANTH PF07651.11 EKG13709.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Epimerase PF01370.16 EKG13711.1 - 6.5e-18 65.0 0.0 9.3e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG13711.1 - 3.6e-12 45.7 0.0 4.3e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EKG13711.1 - 2e-11 43.1 0.0 2.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG13711.1 - 7e-10 39.2 0.6 1.8e-09 37.8 0.4 1.8 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EKG13711.1 - 6.3e-07 29.4 0.3 6.3e-07 29.4 0.2 1.9 3 0 0 3 3 3 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EKG13711.1 - 0.00019 20.4 0.0 0.00037 19.5 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EKG13711.1 - 0.0011 18.6 0.2 0.0026 17.4 0.1 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EKG13711.1 - 0.0018 17.5 0.2 0.015 14.5 0.2 2.3 2 1 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 EKG13711.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EKG13711.1 - 0.083 11.8 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TBPIP PF07106.8 EKG13712.1 - 0.29 10.6 3.3 1.6 8.2 1.2 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EKG13712.1 - 0.77 9.3 5.9 1.3 8.5 4.1 1.4 1 0 0 1 1 1 0 IncA protein DUF605 PF04652.11 EKG13712.1 - 6.5 6.0 17.1 8.7 5.6 11.9 1.2 1 0 0 1 1 1 0 Vta1 like Glyco_transf_90 PF05686.7 EKG13715.1 - 5.5e-28 97.7 0.1 7.8e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EKG13715.1 - 0.029 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 ADH_zinc_N_2 PF13602.1 EKG13717.1 - 3.6e-24 86.0 0.0 8e-24 84.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EKG13717.1 - 7.1e-17 61.1 0.2 1.2e-15 57.2 0.2 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EKG13717.1 - 0.049 13.1 1.0 0.24 10.9 0.4 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RNase_H PF00075.19 EKG13719.1 - 8.1e-15 55.3 0.0 1.5e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG13719.1 - 5.2e-05 22.9 0.2 0.0013 18.4 0.0 2.7 3 0 0 3 3 3 1 Reverse transcriptase-like DUF4350 PF14258.1 EKG13719.1 - 0.0046 17.1 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4350) Methyltransf_24 PF13578.1 EKG13719.1 - 0.014 16.2 0.0 1.7 9.5 0.0 2.6 1 1 1 2 2 2 0 Methyltransferase domain Col_cuticle_N PF01484.12 EKG13719.1 - 0.1 12.2 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Dynamin_N PF00350.18 EKG13721.1 - 1.4e-28 99.7 0.0 3.4e-28 98.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EKG13721.1 - 9.3e-21 73.8 0.1 3e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EKG13721.1 - 0.00066 19.6 0.1 0.0052 16.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2884 PF11101.3 EKG13721.1 - 0.01 15.2 0.0 0.029 13.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) Miro PF08477.8 EKG13721.1 - 0.018 15.5 0.0 0.05 14.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Lyase_1 PF00206.15 EKG13721.1 - 0.089 11.9 0.0 0.27 10.3 0.1 1.6 2 0 0 2 2 2 0 Lyase ADH_zinc_N PF00107.21 EKG13724.1 - 3.9e-13 49.0 1.3 4.6e-13 48.8 0.9 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EKG13724.1 - 0.07 13.1 0.5 0.081 12.9 0.3 1.1 1 0 0 1 1 1 0 NADH(P)-binding MAF_flag10 PF01973.13 EKG13724.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF115 adh_short PF00106.20 EKG13726.1 - 2e-20 73.3 1.7 2.4e-20 73.1 1.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13726.1 - 5.7e-11 42.4 0.7 6.9e-11 42.1 0.5 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG13726.1 - 3.1e-10 40.2 0.0 3.8e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 EKG13727.1 - 7e-11 41.3 0.0 8.8e-11 40.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EKG13728.1 - 6.4e-07 28.7 0.1 2.3e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase FAD_binding_3 PF01494.14 EKG13730.1 - 0.0016 17.5 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EKG13731.1 - 2.3e-14 53.2 0.0 2.1e-09 36.9 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EKG13731.1 - 0.00025 21.3 0.1 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG13731.1 - 0.0015 18.5 0.0 0.0037 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG13731.1 - 0.011 14.7 0.6 0.032 13.1 0.1 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.20 EKG13732.1 - 1.8e-28 99.5 0.8 2.2e-28 99.2 0.6 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13732.1 - 2.1e-13 50.3 0.1 2.5e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG13732.1 - 4.2e-08 33.2 0.0 4.8e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EKG13732.1 - 9.2e-06 25.4 0.1 1.2e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EKG13732.1 - 0.0002 20.8 0.1 0.00041 19.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG13732.1 - 0.00073 18.5 0.1 0.0009 18.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EKG13732.1 - 0.00086 19.6 0.3 0.0013 19.1 0.2 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EKG13732.1 - 0.0015 17.2 0.0 0.0019 16.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DFP PF04127.10 EKG13732.1 - 0.002 17.7 1.1 0.0046 16.5 0.8 1.6 1 1 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 EKG13732.1 - 0.0032 16.4 0.0 0.0034 16.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_18 PF12847.2 EKG13732.1 - 0.0035 17.9 0.1 0.0049 17.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG13732.1 - 0.0043 17.0 0.4 0.006 16.6 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain NmrA PF05368.8 EKG13732.1 - 0.0049 16.1 0.1 0.0064 15.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EKG13732.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.10 EKG13732.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase THF_DHG_CYH_C PF02882.14 EKG13732.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EKG13732.1 - 0.017 15.3 0.2 0.029 14.6 0.1 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 EKG13732.1 - 0.018 14.7 0.4 0.04 13.7 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EKG13732.1 - 0.022 13.8 0.1 0.05 12.7 0.1 1.8 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 EKG13732.1 - 0.025 15.0 0.2 0.046 14.2 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain ApbA PF02558.11 EKG13732.1 - 0.034 13.5 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_11 PF08241.7 EKG13732.1 - 0.041 14.3 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EKG13732.1 - 0.044 13.8 0.1 0.058 13.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ubie_methyltran PF01209.13 EKG13732.1 - 0.08 12.0 0.1 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Urocanase PF01175.13 EKG13732.1 - 0.091 10.7 0.1 0.1 10.6 0.1 1.2 1 0 0 1 1 1 0 Urocanase UDPG_MGDP_dh_N PF03721.9 EKG13732.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.16 EKG13732.1 - 0.2 11.4 0.6 0.33 10.7 0.2 1.4 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_4 PF07993.7 EKG13732.1 - 0.28 10.0 1.1 1.3 7.8 0.8 1.9 1 1 0 1 1 1 0 Male sterility protein rpo30_N PF12410.3 EKG13733.1 - 0.049 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit ketoacyl-synt PF00109.21 EKG13736.1 - 5.8e-72 242.2 0.9 5.8e-72 242.2 0.6 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG13736.1 - 1.6e-37 127.9 0.6 4.3e-37 126.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EKG13736.1 - 1.2e-21 77.4 0.6 2.2e-21 76.5 0.4 1.4 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.7 EKG13736.1 - 6.3e-17 61.8 0.0 1.8e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EKG13736.1 - 4.6e-16 58.8 0.2 2.6e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EKG13736.1 - 2e-10 40.6 0.0 9e-10 38.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG13736.1 - 2.2e-09 37.0 0.0 4.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG13736.1 - 4.7e-08 33.4 0.0 1.3e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EKG13736.1 - 1.3e-06 27.5 0.4 3.4e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EKG13736.1 - 5.4e-06 26.9 0.0 3.9e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG13736.1 - 1.5e-05 25.0 0.7 1.5e-05 25.0 0.5 3.3 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG13736.1 - 6.8e-05 23.1 0.0 0.00024 21.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EKG13736.1 - 0.00042 19.8 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EKG13736.1 - 0.0028 17.3 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EKG13736.1 - 0.056 12.8 0.0 0.095 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EKG13736.1 - 0.097 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FAD_binding_3 PF01494.14 EKG13737.1 - 0.00072 18.7 0.0 0.00093 18.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF2023 PF09633.5 EKG13737.1 - 0.094 12.6 0.2 0.2 11.6 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2023) HET PF06985.6 EKG13738.1 - 2.1e-09 37.6 0.0 2.5e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EKG13739.1 - 9.4e-07 29.0 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AmoC PF04896.7 EKG13739.1 - 0.04 12.9 0.2 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C NUDIX PF00293.23 EKG13740.1 - 3.4e-11 42.9 0.1 5.6e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain DUF2381 PF09544.5 EKG13740.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) MFS_1 PF07690.11 EKG13742.1 - 8.3e-32 110.2 21.4 8.3e-32 110.2 14.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EKG13744.1 - 2e-15 56.3 1.3 2.5e-15 56.0 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG13744.1 - 1.1e-06 27.5 0.8 1.2e-06 27.3 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter YtpI PF14007.1 EKG13744.1 - 0.13 12.2 1.3 0.2 11.5 0.9 1.3 1 0 0 1 1 1 0 YtpI-like protein Fungal_trans PF04082.13 EKG13745.1 - 1.3e-05 24.2 0.0 2.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_9 PF13527.1 EKG13746.1 - 0.00021 21.1 0.0 0.00048 19.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG13746.1 - 0.00049 20.1 0.0 0.00088 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG13746.1 - 0.0014 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ipi1_N PF12333.3 EKG13748.1 - 7.3e-22 77.2 0.5 2.2e-21 75.7 0.1 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 EKG13748.1 - 0.0068 16.6 0.1 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats Robl_LC7 PF03259.12 EKG13749.1 - 1.9e-10 40.1 0.2 7.1e-08 31.9 0.0 2.2 1 1 1 2 2 2 2 Roadblock/LC7 domain DUF1348 PF07080.6 EKG13750.1 - 6.3e-48 162.2 5.9 8.3e-48 161.8 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EKG13750.1 - 1.8e-05 25.0 0.1 3e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EKG13750.1 - 0.0006 19.9 0.1 0.0011 19.1 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 EKG13750.1 - 0.026 14.0 0.1 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Glyco_transf_8 PF01501.15 EKG13751.1 - 3.7e-09 36.2 0.0 9e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Redoxin PF08534.5 EKG13752.1 - 1.5e-35 121.8 0.0 1.7e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EKG13752.1 - 5.8e-12 45.3 0.0 6.8e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family GDI PF00996.13 EKG13753.1 - 2.6e-39 134.7 0.0 5.3e-39 133.7 0.0 1.4 1 1 0 1 1 1 1 GDP dissociation inhibitor BTB PF00651.26 EKG13754.1 - 3.9e-27 94.4 0.0 9.8e-13 48.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 EKG13754.1 - 6e-10 38.4 0.4 2e-05 24.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EKG13754.1 - 8.3e-09 35.6 0.1 2.1e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG13754.1 - 3.4e-08 33.4 0.2 1e-06 28.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG13754.1 - 4.5e-07 30.2 0.1 1.2e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG13754.1 - 6.4e-05 22.8 0.2 0.0038 17.3 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat ClpB_D2-small PF10431.4 EKG13754.1 - 0.036 13.9 0.1 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein Pkinase PF00069.20 EKG13755.1 - 2.7e-60 203.7 0.5 4.1e-60 203.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG13755.1 - 3.9e-36 124.4 0.0 3.2e-23 82.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKG13755.1 - 2.7e-05 23.3 0.0 9.1e-05 21.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Zn_clus PF00172.13 EKG13756.1 - 1e-09 38.1 10.8 1.9e-09 37.2 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP-T3 PF10243.4 EKG13759.1 - 0.047 12.1 7.8 0.066 11.6 5.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DNA_methylase PF00145.12 EKG13760.1 - 1.9e-33 116.0 0.0 1e-20 74.1 0.0 2.1 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 EKG13760.1 - 0.0088 16.0 0.1 0.049 13.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain GATase_2 PF00310.16 EKG13761.1 - 1.6e-14 53.4 0.0 2.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EKG13761.1 - 9.8e-14 51.4 0.0 2.3e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EKG13761.1 - 2.4e-13 49.8 0.0 4e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EKG13761.1 - 4.7e-11 42.5 0.1 9.8e-11 41.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EKG13761.1 - 0.0007 18.3 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PA PF02225.17 EKG13761.1 - 0.0042 16.7 0.3 0.032 13.9 0.1 2.3 1 1 1 2 2 2 1 PA domain PRTase_2 PF15609.1 EKG13761.1 - 0.086 12.1 0.0 0.38 10.0 0.0 1.9 1 1 0 1 1 1 0 Phosphoribosyl transferase UBA PF00627.26 EKG13762.1 - 7.1e-05 22.5 0.1 0.00033 20.4 0.1 2.1 1 1 0 1 1 1 1 UBA/TS-N domain F-box-like PF12937.2 EKG13762.1 - 0.055 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like CorA PF01544.13 EKG13764.1 - 1.1e-11 44.2 0.7 2.3e-11 43.2 0.5 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein AdoMet_MTase PF07757.8 EKG13766.1 - 5.4e-37 126.3 0.0 3.7e-36 123.6 0.0 2.1 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EKG13766.1 - 0.0022 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cupin_2 PF07883.6 EKG13768.1 - 1.4e-27 95.0 1.7 8e-19 66.9 0.7 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EKG13768.1 - 5.6e-05 22.8 0.7 0.0013 18.4 0.3 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EKG13768.1 - 0.00044 19.5 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EKG13768.1 - 0.00093 18.6 0.1 0.033 13.6 0.0 2.3 2 1 0 2 2 2 1 Cupin ARD PF03079.9 EKG13768.1 - 0.12 12.3 0.0 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family Auxin_BP PF02041.11 EKG13768.1 - 0.12 11.8 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Auxin binding protein FAD_binding_3 PF01494.14 EKG13769.1 - 4.7e-07 29.1 0.2 6.3e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG13769.1 - 0.064 12.0 0.0 0.084 11.6 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase DUF1691 PF07950.6 EKG13769.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Epimerase PF01370.16 EKG13770.1 - 0.00017 21.1 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG13770.1 - 0.00044 19.2 0.0 0.0006 18.7 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain SAS4 PF15460.1 EKG13770.1 - 0.041 13.7 0.5 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 FAA_hydrolase PF01557.13 EKG13771.1 - 5.4e-56 189.4 0.0 7.5e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Methyltransf_23 PF13489.1 EKG13774.1 - 0.064 12.9 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain COesterase PF00135.23 EKG13777.1 - 1.3e-96 324.4 0.0 1.7e-96 324.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG13777.1 - 0.0027 17.3 0.2 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG13777.1 - 0.037 13.2 0.7 0.069 12.3 0.5 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MEF2_binding PF09047.5 EKG13778.1 - 0.14 11.7 0.0 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 MEF2 binding Cys_Met_Meta_PP PF01053.15 EKG13780.1 - 4e-117 390.7 0.0 4.9e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EKG13780.1 - 2.6e-08 33.2 0.1 4.2e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EKG13780.1 - 5.3e-08 31.9 0.1 7.8e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EKG13780.1 - 3.8e-05 22.8 1.5 6.7e-05 22.0 1.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EKG13780.1 - 0.0076 14.5 0.8 0.012 13.9 0.3 1.4 1 1 1 2 2 2 1 Methionine gamma-lyase Transketolase_C PF02780.15 EKG13780.1 - 0.02 14.7 0.9 3.9 7.4 0.0 3.4 2 1 2 4 4 4 0 Transketolase, C-terminal domain FAD_oxidored PF12831.2 EKG13780.1 - 0.26 10.3 3.4 0.43 9.6 2.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DZR PF12773.2 EKG13781.1 - 0.045 13.5 0.4 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon Terpene_synth_C PF03936.11 EKG13782.1 - 1.9e-20 73.2 0.2 2.5e-20 72.8 0.2 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 EKG13783.1 - 1.8e-15 57.2 1.8 1.8e-15 57.2 1.3 2.1 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EKG13783.1 - 0.006 16.2 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 EKG13783.1 - 0.0087 16.0 0.6 0.019 15.0 0.4 1.6 1 0 0 1 1 1 1 Methyltransferase domain YjeF_N PF03853.10 EKG13783.1 - 0.052 13.1 0.1 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus p450 PF00067.17 EKG13784.1 - 3.4e-59 200.5 0.0 4.2e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_3_hydrox_C PF05373.6 EKG13784.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 L-proline 3-hydroxylase, C-terminal p450 PF00067.17 EKG13785.1 - 1.5e-45 155.5 0.0 2e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG13786.1 - 5.1e-48 163.7 0.0 6.3e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG13787.1 - 2.9e-66 223.8 0.0 3.6e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EKG13788.1 - 4.2e-10 39.8 1.3 6.3e-10 39.3 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG13788.1 - 5.9e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG13788.1 - 1.6e-05 24.6 0.0 2.9e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FA_desaturase PF00487.19 EKG13789.1 - 3e-27 95.6 22.5 4.2e-27 95.2 15.6 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Abhydrolase_6 PF12697.2 EKG13790.1 - 9.2e-27 94.4 3.1 1.9e-26 93.3 2.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG13790.1 - 2.2e-08 33.9 1.7 2e-07 30.8 0.5 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG13790.1 - 1.6e-07 31.2 0.0 3.3e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG13790.1 - 0.0059 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase BAALC_N PF06989.7 EKG13790.1 - 0.064 13.5 1.3 1.3 9.3 0.0 2.9 3 0 0 3 3 3 0 BAALC N-terminus HAD PF12710.2 EKG13792.1 - 6.6e-14 52.5 0.0 3e-13 50.3 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EKG13792.1 - 4.6e-13 48.7 0.2 2.6e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EKG13792.1 - 5.3e-12 45.5 0.0 1.4e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EKG13792.1 - 1.1e-10 42.3 0.0 8.9e-09 36.0 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG13792.1 - 0.032 13.8 0.2 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase OEP PF02321.13 EKG13793.1 - 0.033 13.7 3.7 0.34 10.4 1.7 2.4 2 0 0 2 2 2 0 Outer membrane efflux protein QueF PF14489.1 EKG13793.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Coat_F PF07875.7 EKG13793.1 - 0.18 11.9 0.0 0.54 10.4 0.0 1.8 1 0 0 1 1 1 0 Coat F domain AA_permease_2 PF13520.1 EKG13795.1 - 7e-50 169.8 49.8 8.6e-50 169.5 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG13795.1 - 1.3e-26 93.0 38.6 1.7e-26 92.6 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease SRF-TF PF00319.13 EKG13796.1 - 1.6e-23 81.7 0.2 2.1e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EKG13796.1 - 0.022 12.8 0.2 0.029 12.4 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3246 PF11596.3 EKG13796.1 - 0.057 12.7 0.1 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Tetraspannin PF00335.15 EKG13797.1 - 3e-11 43.0 3.1 4.1e-11 42.5 2.2 1.1 1 0 0 1 1 1 1 Tetraspanin family MFS_1 PF07690.11 EKG13798.1 - 8.2e-52 176.0 42.6 2.5e-50 171.1 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG13798.1 - 4.2e-13 48.6 14.6 4e-11 42.1 4.4 3.2 2 1 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.15 EKG13798.1 - 0.0033 15.5 2.2 0.39 8.7 0.4 3.5 3 1 1 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family Rpr2 PF04032.11 EKG13799.1 - 2.2e-23 81.9 0.0 4.2e-23 81.0 0.0 1.5 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain NinG PF05766.7 EKG13799.1 - 0.022 14.5 0.3 0.022 14.5 0.2 2.1 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein Prim_Zn_Ribbon PF08273.7 EKG13799.1 - 0.2 11.7 1.1 21 5.2 0.0 2.9 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DEAD PF00270.24 EKG13800.1 - 2.1e-37 128.1 0.1 3.7e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG13800.1 - 6.8e-24 83.5 0.0 9.6e-23 79.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG13800.1 - 2e-07 31.0 0.0 4.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EKG13800.1 - 0.01 14.8 0.2 0.22 10.5 0.1 2.3 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit ApbA_C PF08546.6 EKG13801.1 - 1.1e-25 90.0 0.0 1.7e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EKG13801.1 - 2.8e-24 85.2 0.0 4.3e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Hexokinase_2 PF03727.11 EKG13802.1 - 3.3e-68 229.4 0.0 6.6e-68 228.5 0.0 1.5 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EKG13802.1 - 2.5e-65 219.6 0.1 7.6e-65 218.0 0.0 1.9 2 0 0 2 2 2 1 Hexokinase DUF1690 PF07956.6 EKG13803.1 - 2.2e-29 102.2 11.8 1.4e-16 60.7 1.5 2.1 1 1 1 2 2 2 2 Protein of Unknown function (DUF1690) Caprin-1_C PF12287.3 EKG13803.1 - 0.068 12.5 0.4 0.082 12.2 0.3 1.1 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Phage_GPO PF05929.6 EKG13803.1 - 0.092 11.9 5.1 0.11 11.7 3.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1525 PF07511.6 EKG13803.1 - 0.41 10.6 5.0 0.93 9.5 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) Matrilin_ccoil PF10393.4 EKG13803.1 - 2.3 7.6 5.5 0.55 9.6 0.2 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4407 PF14362.1 EKG13803.1 - 2.5 6.9 6.9 3.2 6.6 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vpu PF00558.14 EKG13803.1 - 2.7 7.5 6.9 0.4 10.2 0.3 2.2 1 1 1 2 2 2 0 Vpu protein DUF4404 PF14357.1 EKG13803.1 - 2.8 8.4 13.5 0.75 10.2 3.8 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) FUSC PF04632.7 EKG13803.1 - 4.3 5.6 7.7 5.2 5.3 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nefa_Nip30_N PF10187.4 EKG13803.1 - 6.1 7.0 10.6 11 6.2 7.4 1.5 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 COesterase PF00135.23 EKG13804.1 - 7.2e-99 331.9 0.0 1.4e-98 330.9 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG13804.1 - 4.3e-05 23.1 0.1 0.0005 19.7 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG13804.1 - 0.0026 17.0 1.5 0.0057 15.9 0.5 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Sulfatase PF00884.18 EKG13805.1 - 1.6e-35 122.8 0.0 2.1e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EKG13805.1 - 0.00059 18.3 0.0 0.00077 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EKG13805.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EKG13805.1 - 0.019 15.2 0.1 0.39 11.0 0.1 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Sulfatase PF00884.18 EKG13806.1 - 1.6e-32 112.9 0.0 2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Sulfatase MFS_1 PF07690.11 EKG13808.1 - 1.9e-09 36.6 6.3 2.2e-09 36.5 4.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LtrA PF06772.6 EKG13809.1 - 7.8e-10 38.1 1.0 9.4e-10 37.9 0.7 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4233 PF14017.1 EKG13809.1 - 0.24 11.3 2.9 0.35 10.7 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) p450 PF00067.17 EKG13810.1 - 1.9e-57 194.8 0.0 2.2e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.1 EKG13812.1 - 2e-11 43.8 0.2 3e-11 43.3 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG13812.1 - 4.5e-11 42.6 0.1 6.8e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EKG13812.1 - 0.0028 17.6 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG13812.1 - 0.0037 17.3 0.0 0.0059 16.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG13812.1 - 0.0044 17.1 0.0 0.0052 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG13812.1 - 0.0058 16.4 0.0 0.007 16.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SEN1_N PF12726.2 EKG13814.1 - 1.1e-177 592.4 16.7 1.3e-177 592.1 11.6 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EKG13814.1 - 2.2e-71 240.1 0.9 2.2e-71 240.1 0.6 3.0 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EKG13814.1 - 2.1e-63 213.3 0.0 1.5e-62 210.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG13814.1 - 3.3e-12 45.9 0.1 1.8e-11 43.6 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EKG13814.1 - 2.2e-08 33.9 4.4 7.1e-06 25.7 0.1 3.3 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EKG13814.1 - 3e-05 23.6 0.8 0.058 12.9 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EKG13814.1 - 6.1e-05 22.5 0.3 0.002 17.6 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EKG13814.1 - 0.0011 18.3 1.4 0.0011 18.3 1.0 4.0 3 2 0 3 3 3 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 EKG13814.1 - 0.0024 17.7 0.0 0.014 15.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EKG13814.1 - 0.0051 16.2 0.3 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EKG13814.1 - 0.029 13.4 0.0 0.056 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF447 PF04289.7 EKG13814.1 - 0.05 13.1 0.1 0.92 9.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF447) AAA_23 PF13476.1 EKG13814.1 - 0.23 11.7 10.0 0.054 13.8 0.3 2.9 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.13 EKG13815.1 - 5.7 6.9 11.2 0.54 10.2 3.5 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EKG13815.1 - 8.8 6.5 12.9 0.21 11.7 2.0 2.5 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region DUF1940 PF09155.5 EKG13818.1 - 0.079 12.7 0.1 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) Abhydrolase_6 PF12697.2 EKG13822.1 - 2.2e-07 30.9 0.0 2.5e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13822.1 - 6.2e-05 22.7 0.0 7.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family RapA_C PF12137.3 EKG13822.1 - 0.078 11.7 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal SnoaL_4 PF13577.1 EKG13825.1 - 9.8e-24 83.6 0.1 1.3e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EKG13825.1 - 0.00012 22.4 0.1 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EKG13825.1 - 0.027 14.6 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EKG13825.1 - 0.05 13.6 0.3 0.18 11.8 0.2 1.8 1 1 0 1 1 1 0 SnoaL-like domain Lyase_1 PF00206.15 EKG13826.1 - 1.3e-43 149.4 0.0 2e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EKG13826.1 - 2.1e-22 78.9 0.0 2.3e-21 75.5 0.0 2.5 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HET PF06985.6 EKG13827.1 - 2.4e-31 108.7 0.0 4.9e-31 107.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3446 PF11928.3 EKG13827.1 - 0.15 12.2 10.9 0.32 11.2 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF515 PF04415.7 EKG13827.1 - 3.9 5.5 6.0 5.9 5.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cellulase PF00150.13 EKG13828.1 - 0.13 11.3 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) GMC_oxred_N PF00732.14 EKG13830.1 - 2.8e-38 131.7 0.0 1.6e-29 103.0 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EKG13830.1 - 0.00032 20.6 0.8 0.0007 19.5 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG13830.1 - 0.0013 17.7 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EKG13830.1 - 0.0025 16.8 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG13830.1 - 0.015 14.1 1.5 0.019 13.8 0.5 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EKG13830.1 - 0.019 13.4 0.1 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EKG13830.1 - 0.065 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG13830.1 - 0.078 12.8 0.1 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mid2 PF04478.7 EKG13831.1 - 0.006 16.0 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EKG13831.1 - 0.013 14.8 0.3 0.022 14.0 0.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EKG13831.1 - 0.03 12.5 0.0 0.036 12.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EKG13831.1 - 0.053 13.1 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family MLANA PF14991.1 EKG13831.1 - 0.083 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein melan-A Glyco_hydro_31 PF01055.21 EKG13832.1 - 3.1e-42 144.9 0.6 3.8e-42 144.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AhpC-TSA_2 PF13911.1 EKG13833.1 - 8.4e-23 80.4 0.0 1.3e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EKG13833.1 - 0.0027 17.4 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKG13833.1 - 0.0061 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Redoxin TPR_11 PF13414.1 EKG13834.1 - 0.56 9.8 4.6 6.8 6.4 0.6 2.3 2 0 0 2 2 2 0 TPR repeat AMP-binding PF00501.23 EKG13836.1 - 4.4e-99 331.7 0.0 5.4e-99 331.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG13836.1 - 5.9e-13 49.5 0.1 5.5e-12 46.4 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2554 PF10829.3 EKG13836.1 - 0.081 13.0 0.2 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2554) DSBA PF01323.15 EKG13837.1 - 1.9e-18 66.7 0.0 2.2e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain ADH_N PF08240.7 EKG13838.1 - 8.7e-17 60.8 1.1 6.7e-16 58.0 0.8 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SnoaL_4 PF13577.1 EKG13839.1 - 3.2e-22 78.7 0.0 4.6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EKG13839.1 - 0.0026 17.9 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 EKG13839.1 - 0.032 13.8 0.0 0.081 12.5 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase SSXT PF05030.7 EKG13839.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) CorA PF01544.13 EKG13840.1 - 1.2e-06 27.8 0.3 2.9e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3324 PF11797.3 EKG13841.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminal (DUF3324) Pkinase PF00069.20 EKG13842.1 - 5.5e-09 35.5 0.1 5.9e-09 35.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG13842.1 - 0.0023 17.0 0.0 0.0023 17.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase GFA PF04828.9 EKG13845.1 - 3.1e-09 36.6 0.3 3.1e-09 36.6 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme RNase_H PF00075.19 EKG13846.1 - 1.3e-17 64.3 0.0 2.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 RNase H JmjC PF02373.17 EKG13847.1 - 4.1e-24 85.0 0.0 6.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Hexapep PF00132.19 EKG13848.1 - 1.4e-15 55.9 13.1 1.7e-07 30.4 0.7 3.4 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKG13848.1 - 1.8e-15 56.1 12.7 5.5e-08 32.2 4.0 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EKG13848.1 - 4.4e-05 23.3 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Ferric_reduct PF01794.14 EKG13849.1 - 1.8e-11 44.2 6.1 1.8e-11 44.2 4.2 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EKG13849.1 - 2e-09 37.5 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG13849.1 - 4.5e-09 36.1 0.0 8.5e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF869 PF05911.6 EKG13850.1 - 0.00056 18.2 1.9 0.00069 17.9 1.3 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) GOLGA2L5 PF15070.1 EKG13850.1 - 0.061 11.8 6.1 0.03 12.8 0.7 1.9 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Atg14 PF10186.4 EKG13850.1 - 0.061 12.2 6.0 1.1 8.1 0.3 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FtsK_SpoIIIE_N PF12538.3 EKG13850.1 - 0.088 12.9 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 DNA transporter IncA PF04156.9 EKG13850.1 - 0.13 11.8 9.3 0.16 11.5 6.4 1.1 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EKG13850.1 - 0.41 11.0 5.6 0.86 9.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 EKG13850.1 - 0.46 10.5 5.8 0.93 9.5 1.1 2.3 2 1 0 2 2 2 0 Cortexillin I, coiled coil SlyX PF04102.7 EKG13850.1 - 0.64 10.4 8.8 0.33 11.3 2.4 2.7 2 1 1 3 3 3 0 SlyX DivIVA PF05103.8 EKG13850.1 - 1.3 9.0 8.2 0.61 10.1 0.8 2.1 2 0 0 2 2 2 0 DivIVA protein TMF_DNA_bd PF12329.3 EKG13850.1 - 2.1 8.1 7.1 0.79 9.5 0.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding HrpB7 PF09486.5 EKG13850.1 - 2.3 8.1 10.4 12 5.7 4.5 2.8 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) bZIP_Maf PF03131.12 EKG13850.1 - 3.8 7.8 8.8 0.32 11.3 1.6 2.4 2 1 1 3 3 3 0 bZIP Maf transcription factor priB_priC PF07445.7 EKG13850.1 - 5.8 6.3 10.4 1.6 8.2 1.4 2.0 1 1 1 2 2 2 0 Primosomal replication protein priB and priC CENP-Q PF13094.1 EKG13850.1 - 7.7 6.5 13.1 4.1 7.4 3.3 2.6 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit YscO PF07321.7 EKG13850.1 - 8.1 6.2 12.6 0.32 10.7 2.7 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO Coatamer_beta_C PF07718.7 EKG13852.1 - 0.1 12.2 0.1 0.1 12.2 0.1 2.5 2 1 0 3 3 3 0 Coatomer beta C-terminal region DUF342 PF03961.8 EKG13852.1 - 2 6.7 39.9 0.43 8.9 8.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF342) IncA PF04156.9 EKG13852.1 - 2.5 7.6 62.8 1 8.9 19.0 3.4 1 1 2 3 3 3 0 IncA protein AAA_27 PF13514.1 EKG13852.1 - 3.3 5.2 51.1 0.074 10.7 11.4 2.1 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 EKG13852.1 - 3.7 6.6 54.0 0.36 9.9 14.3 3.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 EKG13852.1 - 5.7 5.3 47.3 4.9 5.5 19.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Lebercilin PF15619.1 EKG13852.1 - 6.7 6.0 59.3 10 5.4 5.1 4.1 1 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF3723 PF12520.3 EKG13853.1 - 1.2e-21 76.8 0.0 1.5e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Patatin PF01734.17 EKG13854.1 - 2e-14 54.0 0.0 4.1e-13 49.7 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Pkinase_Tyr PF07714.12 EKG13855.1 - 2.2e-22 79.4 0.0 5.4e-22 78.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EKG13855.1 - 6.2e-22 77.9 0.0 1.4e-21 76.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EKG13855.1 - 5.7e-06 25.4 0.0 1.3e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like PIP49_C PF12260.3 EKG13855.1 - 0.059 12.7 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kdo PF06293.9 EKG13855.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FragX_IP PF05994.6 EKG13860.1 - 0.018 12.8 0.0 0.022 12.5 0.0 1.0 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Nro1 PF12753.2 EKG13860.1 - 0.019 13.9 0.5 0.024 13.6 0.3 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 Laminin_I PF06008.9 EKG13860.1 - 0.032 13.5 0.3 0.039 13.2 0.2 1.1 1 0 0 1 1 1 0 Laminin Domain I DUF2383 PF09537.5 EKG13860.1 - 0.035 14.3 0.2 0.049 13.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) Dna2 PF08696.6 EKG13860.1 - 0.041 13.1 0.1 0.051 12.8 0.1 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 DUF2600 PF10776.4 EKG13860.1 - 0.065 12.0 0.1 0.077 11.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) DUF87 PF01935.12 EKG13860.1 - 0.11 12.3 0.1 0.13 12.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 DivIC PF04977.10 EKG13861.1 - 0.0093 15.4 7.4 0.027 13.9 0.8 2.2 2 0 0 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 EKG13861.1 - 0.021 14.7 1.3 0.021 14.7 0.9 1.7 2 0 0 2 2 2 0 bZIP transcription factor DUF4200 PF13863.1 EKG13861.1 - 0.028 14.3 1.3 0.028 14.3 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.3 EKG13861.1 - 0.035 14.0 3.9 0.047 13.6 2.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.4 EKG13861.1 - 0.14 11.0 4.4 0.19 10.6 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 MbeD_MobD PF04899.7 EKG13861.1 - 0.21 11.5 6.7 0.12 12.2 0.7 2.2 1 1 1 2 2 2 0 MbeD/MobD like TPR_MLP1_2 PF07926.7 EKG13861.1 - 0.58 9.9 8.9 0.92 9.2 6.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 EKG13861.1 - 0.77 9.7 5.4 3.8 7.5 3.6 2.2 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF904 PF06005.7 EKG13861.1 - 1.4 9.2 6.3 2.8 8.3 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) FlxA PF14282.1 EKG13861.1 - 1.4 8.8 10.2 0.7 9.8 0.8 2.3 2 0 0 2 2 2 0 FlxA-like protein Sorb PF02208.11 EKG13863.1 - 0.08 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Sorbin homologous domain Catalase PF00199.14 EKG13864.1 - 1.1e-160 534.6 0.3 1.5e-160 534.0 0.2 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EKG13864.1 - 4.2e-20 71.3 0.1 8.5e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EKG13864.1 - 3.6e-11 42.7 0.1 7.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EKG13864.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase SNF2_N PF00176.18 EKG13866.1 - 2.1e-70 236.9 0.0 2.1e-70 236.9 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG13866.1 - 1.4e-14 53.6 0.0 7.9e-14 51.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG13866.1 - 3.7e-09 36.6 0.4 1.3e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKG13866.1 - 3.3e-07 29.9 0.0 7.9e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 EKG13866.1 - 0.00095 18.9 10.8 0.00095 18.9 7.5 2.8 1 1 1 2 2 2 1 HSA DEAD_2 PF06733.10 EKG13866.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 NDUF_B8 PF05821.6 EKG13867.1 - 4.9e-07 29.5 0.2 7.3e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) MFS_1 PF07690.11 EKG13868.1 - 2.1e-14 53.0 25.1 8.4e-14 51.0 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.6 EKG13868.1 - 0.4 9.9 4.2 0.26 10.5 1.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3474 PF11960.3 EKG13869.1 - 0.41 10.6 5.5 0.093 12.7 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) KAR9 PF08580.5 EKG13869.1 - 7.9 4.6 9.8 9.7 4.3 6.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 NAD_binding_1 PF00175.16 EKG13870.1 - 9.5e-32 109.8 0.0 2.4e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EKG13870.1 - 1.4e-22 79.6 0.0 2.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EKG13870.1 - 6e-09 35.9 0.0 1.3e-05 25.1 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EKG13870.1 - 0.00021 21.2 0.0 0.00055 19.8 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain zf-C3HC4_2 PF13923.1 EKG13871.1 - 0.0054 16.7 5.2 0.017 15.1 3.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG13871.1 - 0.017 14.7 3.2 0.047 13.3 2.2 1.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKG13871.1 - 0.11 12.3 6.0 0.3 10.9 4.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EKG13871.1 - 0.64 9.9 9.5 3.8 7.4 7.0 2.0 1 1 1 2 2 2 0 Ring finger domain Ice_nucleation PF00818.12 EKG13871.1 - 0.99 8.8 5.7 1.6 8.1 4.0 1.3 1 0 0 1 1 1 0 Ice nucleation protein repeat zf-RING_5 PF14634.1 EKG13871.1 - 3.1 7.5 7.3 15 5.4 5.2 2.0 1 1 1 2 2 2 0 zinc-RING finger domain SCP2 PF02036.12 EKG13872.1 - 1.7e-26 92.4 0.5 1.9e-26 92.3 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EKG13872.1 - 1.4e-07 31.5 0.2 1.7e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Shugoshin_C PF07557.6 EKG13873.1 - 0.046 13.1 0.2 0.19 11.2 0.1 2.1 1 0 0 1 1 1 0 Shugoshin C terminus F-box-like PF12937.2 EKG13873.1 - 0.09 12.5 0.8 0.29 10.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like HATPase_c PF02518.21 EKG13874.1 - 1.9e-27 95.1 0.0 1.2e-26 92.5 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG13874.1 - 2e-27 95.3 0.1 3.7e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EKG13874.1 - 7.7e-13 48.2 0.0 2.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EKG13874.1 - 1.5e-05 25.0 7.8 0.021 14.9 0.0 3.6 3 0 0 3 3 3 2 HAMP domain zf-C2H2_jaz PF12171.3 EKG13875.1 - 2.7 8.2 11.3 0.27 11.4 3.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Chromo PF00385.19 EKG13876.1 - 2.5e-09 36.6 0.1 4.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.7 EKG13878.1 - 2.4e-14 53.3 0.0 5.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EKG13878.1 - 2.2e-09 37.5 0.3 8.9e-09 35.5 0.3 1.9 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 EKG13878.1 - 6.1e-06 25.3 0.0 1.4e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 EKG13878.1 - 3.9e-05 23.8 0.0 0.00023 21.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG13878.1 - 0.0016 18.5 0.0 0.0041 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG13878.1 - 0.0031 17.2 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKG13878.1 - 0.0034 16.9 0.1 0.0063 16.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKG13878.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 EKG13878.1 - 0.035 14.9 0.0 0.11 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EKG13878.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.1 EKG13878.1 - 0.063 13.1 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.13 EKG13878.1 - 0.063 12.7 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 Cytidylate kinase HCBP_related PF06594.6 EKG13878.1 - 0.094 12.3 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain AAA_18 PF13238.1 EKG13878.1 - 0.1 12.9 0.0 0.31 11.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 EKG13878.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase NAD_binding_10 PF13460.1 EKG13879.1 - 8.5e-21 74.7 7.0 1.1e-20 74.4 4.8 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG13879.1 - 3.6e-14 52.6 0.0 4.4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EKG13879.1 - 0.00052 19.5 0.2 0.0095 15.3 0.0 2.5 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKG13879.1 - 0.00062 19.4 6.0 0.11 12.1 4.2 2.2 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EKG13879.1 - 0.012 14.3 0.0 0.052 12.2 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EKG13879.1 - 0.014 15.3 8.2 0.056 13.3 0.0 2.7 1 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EKG13879.1 - 0.024 13.5 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF2404 PF10296.4 EKG13882.1 - 0.00012 22.1 0.0 0.0052 16.8 0.0 2.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) AvrE PF11725.3 EKG13882.1 - 0.018 12.1 0.6 0.025 11.6 0.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor Hamartin PF04388.7 EKG13884.1 - 0.094 11.3 24.6 0.14 10.8 17.0 1.2 1 0 0 1 1 1 0 Hamartin protein Ferric_reduct PF01794.14 EKG13885.1 - 3.1e-18 66.0 9.6 3.1e-18 66.0 6.6 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EKG13885.1 - 3.8e-13 49.1 0.0 8.1e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EKG13885.1 - 1.1e-09 38.4 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF1469 PF07332.6 EKG13885.1 - 0.38 10.4 0.0 0.38 10.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) WTF PF03303.8 EKG13885.1 - 0.38 10.1 5.1 0.38 10.1 0.1 2.2 2 0 0 2 2 2 0 WTF protein SHS2_Rpb7-N PF03876.12 EKG13886.1 - 0.00013 22.0 0.0 0.00075 19.5 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 FAM163 PF15069.1 EKG13886.1 - 0.2 12.2 0.7 0.32 11.5 0.5 1.3 1 0 0 1 1 1 0 FAM163 family BRF1 PF07741.8 EKG13886.1 - 4.9 7.4 17.1 16 5.8 10.0 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Peptidase_S64 PF08192.6 EKG13886.1 - 5.7 5.1 5.9 7.9 4.6 4.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DnaJ PF00226.26 EKG13887.1 - 2.6e-13 49.4 1.5 3.4e-13 49.1 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain DUF2062 PF09835.4 EKG13887.1 - 0.065 12.8 2.0 0.093 12.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) zf-CCHC PF00098.18 EKG13888.1 - 1.8e-32 109.7 69.2 6.7e-07 28.9 0.9 7.5 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EKG13888.1 - 1.5e-05 24.5 56.1 0.033 13.8 0.6 7.2 6 1 1 7 7 7 6 Zinc knuckle Nnf1 PF03980.9 EKG13890.1 - 1.9e-22 79.3 0.6 2.8e-22 78.7 0.4 1.3 1 0 0 1 1 1 1 Nnf1 Syntaxin-6_N PF09177.6 EKG13890.1 - 0.095 13.1 1.3 0.16 12.3 0.2 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2051 PF09738.4 EKG13890.1 - 0.25 10.5 2.4 0.12 11.6 0.2 1.4 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) CENP-F_leu_zip PF10473.4 EKG13890.1 - 0.6 9.9 4.8 0.29 10.9 1.1 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.7 EKG13890.1 - 3.7 7.9 5.3 2.2 8.7 1.1 2.2 2 0 0 2 2 2 0 SlyX Mo-co_dimer PF03404.11 EKG13892.1 - 7.4e-24 83.8 0.1 1e-23 83.3 0.1 1.1 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain F-box-like PF12937.2 EKG13893.1 - 0.042 13.5 0.3 0.097 12.4 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EKG13893.1 - 1.2 8.8 8.2 0.11 12.1 0.4 2.9 3 1 0 3 3 3 0 F-box domain Erf4 PF10256.4 EKG13895.1 - 0.043 13.6 0.0 0.8 9.5 0.0 2.7 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF4407 PF14362.1 EKG13895.1 - 0.18 10.7 6.0 0.25 10.2 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM176 PF14851.1 EKG13895.1 - 0.35 10.5 4.3 0.55 9.9 3.0 1.2 1 0 0 1 1 1 0 FAM176 family Fungal_trans PF04082.13 EKG13896.1 - 2.8e-21 75.5 0.0 6.1e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG13896.1 - 1.1e-09 38.0 10.2 1.9e-09 37.2 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EKG13897.1 - 0.0012 18.6 0.5 4.8 7.2 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat p450 PF00067.17 EKG13898.1 - 3.5e-73 246.7 0.0 4.6e-73 246.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 EKG13899.1 - 2.5e-22 79.3 0.0 8.4e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain zf-Apc11 PF12861.2 EKG13900.1 - 2e-43 146.1 9.6 2.2e-43 145.9 6.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EKG13900.1 - 9.2e-33 112.1 10.7 1.1e-32 111.9 7.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EKG13900.1 - 6e-09 35.5 13.9 1.2e-08 34.6 9.6 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKG13900.1 - 4e-06 26.3 11.8 8.3e-06 25.3 8.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG13900.1 - 1.9e-05 24.5 12.6 0.00023 21.0 8.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG13900.1 - 3.6e-05 23.3 13.5 0.0012 18.4 9.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG13900.1 - 7.7e-05 22.3 13.1 0.00031 20.4 9.1 1.9 1 1 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 EKG13900.1 - 0.00015 21.6 12.4 0.0012 18.7 8.6 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EKG13900.1 - 0.0022 17.8 2.8 0.0022 17.8 1.9 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EKG13900.1 - 0.0025 17.3 12.1 0.11 12.0 6.6 2.6 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EKG13900.1 - 0.0032 17.2 2.0 0.0032 17.2 1.4 1.8 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EKG13900.1 - 0.0053 16.2 5.3 0.0097 15.4 3.6 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 EKG13900.1 - 0.013 15.1 7.3 0.036 13.7 2.2 2.3 2 0 0 2 2 2 0 HIT zinc finger zf-RING-like PF08746.6 EKG13900.1 - 0.013 15.5 9.1 0.013 15.5 6.3 1.8 1 1 1 2 2 2 0 RING-like domain Rad50_zn_hook PF04423.9 EKG13900.1 - 0.043 13.2 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_UBOX PF13445.1 EKG13900.1 - 0.28 10.9 8.3 0.19 11.4 4.0 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EKG13900.1 - 0.66 10.1 10.2 11 6.2 7.4 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EKG13900.1 - 0.67 9.7 0.1 0.67 9.7 0.1 3.1 2 1 0 2 2 1 0 Prokaryotic RING finger family 1 RecR PF02132.10 EKG13900.1 - 0.75 9.2 7.4 0.52 9.7 0.2 2.9 3 0 0 3 3 3 0 RecR protein RINGv PF12906.2 EKG13900.1 - 0.77 9.8 13.9 4.4 7.4 9.7 2.1 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.24 EKG13900.1 - 3.2 7.5 16.4 26 4.6 11.4 2.2 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.1 EKG13900.1 - 4 7.4 10.2 32 4.5 7.2 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-P11 PF03854.9 EKG13900.1 - 5.2 6.6 11.3 12 5.4 4.1 2.6 1 1 1 2 2 2 0 P-11 zinc finger DZR PF12773.2 EKG13900.1 - 8.3 6.3 13.0 4.5e+02 0.7 9.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon Cupin_2 PF07883.6 EKG13902.1 - 4.3e-11 42.1 0.1 5.6e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 EKG13902.1 - 3.3e-06 26.5 0.1 0.076 12.4 0.0 2.6 2 1 0 2 2 2 2 Cupin Cupin_6 PF12852.2 EKG13902.1 - 0.00032 20.3 0.0 0.067 12.7 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EKG13902.1 - 0.00094 18.5 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 EKG13902.1 - 0.014 15.0 0.1 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain CDC48_2 PF02933.12 EKG13902.1 - 0.025 14.2 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 ARD PF03079.9 EKG13902.1 - 0.14 12.1 0.1 12 5.7 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family CDK2AP PF09806.4 EKG13902.1 - 0.78 9.9 2.6 13 5.9 1.8 2.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Glyco_hydro_3 PF00933.16 EKG13903.1 - 1.3e-47 162.2 0.0 1.7e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG13903.1 - 2.4e-46 158.0 0.0 4.2e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG13903.1 - 1.5e-27 95.3 0.5 4.5e-27 93.7 0.5 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain Polyketide_cyc2 PF10604.4 EKG13904.1 - 6.2e-09 36.1 6.0 1.9e-08 34.5 4.2 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EKG13904.1 - 2.7e-05 24.1 0.2 4.6e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.6 EKG13904.1 - 0.04 14.0 1.2 0.37 10.8 0.0 2.2 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein ASFV_360 PF01671.11 EKG13905.1 - 0.08 12.3 0.5 0.12 11.7 0.3 1.2 1 0 0 1 1 1 0 African swine fever virus multigene family 360 protein DUF4162 PF13732.1 EKG13907.1 - 0.047 14.1 0.0 0.072 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Glyco_hydro_56 PF01630.13 EKG13907.1 - 0.16 10.5 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Hyaluronidase PAN_4 PF14295.1 EKG13908.1 - 0.00024 20.7 0.3 0.00024 20.7 0.2 1.8 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.7 EKG13908.1 - 0.012 15.2 1.7 0.013 15.0 0.2 1.8 2 0 0 2 2 2 0 PAN-like domain MFS_1 PF07690.11 EKG13909.1 - 4.2e-34 117.7 36.3 4.2e-34 117.7 25.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG13909.1 - 7.6e-11 41.2 5.8 7.6e-11 41.2 4.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 EKG13909.1 - 0.31 9.0 4.3 0.18 9.8 0.3 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Xpo1 PF08389.7 EKG13910.1 - 6.8e-22 77.9 1.2 2.7e-21 76.0 0.1 2.7 3 0 0 3 3 3 1 Exportin 1-like protein DUF3597 PF12200.3 EKG13910.1 - 0.022 15.1 0.1 0.075 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Alk_phosphatase PF00245.15 EKG13911.1 - 2.2e-69 234.2 0.5 6.3e-69 232.6 0.3 1.7 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EKG13911.1 - 1.7e-06 27.4 0.5 4.3e-06 26.1 0.3 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EKG13911.1 - 0.00011 21.6 0.2 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EKG13911.1 - 0.0036 15.7 0.1 0.0054 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 EKG13911.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PAN_4 PF14295.1 EKG13912.1 - 0.074 12.7 2.6 0.13 11.9 1.1 1.9 2 0 0 2 2 2 0 PAN domain PAN_4 PF14295.1 EKG13913.1 - 5.6e-20 70.7 36.0 1.1e-05 25.0 2.5 6.0 6 0 0 6 6 6 5 PAN domain PAN_3 PF08277.7 EKG13913.1 - 3.9e-06 26.3 27.8 0.19 11.3 0.1 6.3 5 0 0 5 5 5 5 PAN-like domain PAN_4 PF14295.1 EKG13914.1 - 4.4e-14 51.9 12.9 4.4e-06 26.3 0.2 3.5 3 0 0 3 3 3 3 PAN domain PAN_3 PF08277.7 EKG13914.1 - 0.0042 16.6 14.2 0.005 16.4 0.1 3.8 4 0 0 4 4 4 3 PAN-like domain adh_short PF00106.20 EKG13915.1 - 2.3e-22 79.6 0.0 3.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13915.1 - 2.3e-08 33.8 0.0 3.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG13915.1 - 4.1e-08 33.3 0.0 5.4e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG13915.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG13915.1 - 0.0098 15.1 0.1 0.015 14.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family AceK PF06315.6 EKG13915.1 - 0.11 10.7 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) CoA_binding_2 PF13380.1 EKG13915.1 - 0.16 12.1 1.5 0.74 9.9 0.6 2.3 2 1 0 2 2 2 0 CoA binding domain ATP_transf PF09830.4 EKG13917.1 - 2.6e-14 52.7 0.0 4.8e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase Peptidase_M22 PF00814.20 EKG13918.1 - 6.3e-39 134.0 0.1 2.3e-17 63.3 0.0 3.8 2 1 1 3 3 3 3 Glycoprotease family YycC PF14174.1 EKG13918.1 - 0.0051 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 YycC-like protein DUF3336 PF11815.3 EKG13919.1 - 1e-47 161.3 6.0 1.5e-47 160.7 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EKG13919.1 - 1.1e-20 74.4 1.5 3.6e-20 72.7 0.1 2.4 3 0 0 3 3 3 1 Patatin-like phospholipase DUF2721 PF11026.3 EKG13919.1 - 0.11 12.1 0.2 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) adh_short_C2 PF13561.1 EKG13920.1 - 1e-28 100.7 0.0 1.2e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG13920.1 - 4e-28 98.4 0.1 5e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG13920.1 - 1.7e-14 53.8 0.1 2.4e-14 53.4 0.1 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EKG13920.1 - 0.0038 16.4 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EKG13920.1 - 0.011 15.2 0.1 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.1 EKG13920.1 - 0.05 13.7 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Eno-Rase_NADH_b PF12242.3 EKG13920.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EKG13920.1 - 0.11 12.1 0.2 0.68 9.5 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OTCace PF00185.19 EKG13920.1 - 0.12 12.1 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain TFIIA PF03153.8 EKG13923.1 - 6.4e-49 167.8 31.2 8.3e-48 164.1 21.6 1.9 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EKG13923.1 - 0.17 10.0 35.4 0.2 9.8 24.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3617 PF12276.3 EKG13923.1 - 5.9 6.3 12.9 0.99 8.8 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) SAD_SRA PF02182.12 EKG13924.1 - 5.7e-22 77.6 0.0 8.8e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain SLX9 PF15341.1 EKG13925.1 - 2.9e-31 108.4 6.9 5.1e-31 107.6 4.8 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Fringe PF02434.11 EKG13925.1 - 1.5e-06 27.6 0.3 1.4e-05 24.4 0.2 2.1 1 1 0 1 1 1 1 Fringe-like PAN_4 PF14295.1 EKG13925.1 - 0.02 14.5 1.1 0.052 13.2 0.7 1.6 1 0 0 1 1 1 0 PAN domain Kunitz_BPTI PF00014.18 EKG13925.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain GATA PF00320.22 EKG13926.1 - 3.7e-16 58.1 5.5 7.8e-16 57.1 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 EKG13926.1 - 3.9e-11 42.8 0.0 1.1e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EKG13926.1 - 4.2e-10 39.3 0.1 1.4e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EKG13926.1 - 1.2e-09 38.4 0.0 5.4e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EKG13926.1 - 3.5e-06 27.0 0.0 7.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EKG13926.1 - 9.1e-05 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 EKG13926.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 PAS domain DUF4428 PF14471.1 EKG13926.1 - 0.16 11.7 4.0 0.1 12.3 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) AAA_23 PF13476.1 EKG13927.1 - 5e-22 79.2 13.1 5e-22 79.2 9.0 8.6 2 1 3 5 5 3 1 AAA domain AAA_13 PF13166.1 EKG13927.1 - 8.7e-16 57.5 125.9 1e-05 24.2 17.3 7.0 2 1 3 6 6 6 4 AAA domain SbcCD_C PF13558.1 EKG13927.1 - 6.5e-12 45.2 0.0 3e-11 43.1 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EKG13927.1 - 3.8e-08 33.6 7.8 0.00033 20.7 0.0 4.0 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 EKG13927.1 - 7.8e-06 25.2 0.1 7.8e-06 25.2 0.0 4.1 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain MobB PF03205.9 EKG13927.1 - 0.00057 19.6 1.7 0.28 10.8 0.0 3.6 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B Spc7 PF08317.6 EKG13927.1 - 0.0017 17.1 12.7 0.0017 17.1 8.8 8.8 2 2 5 9 9 9 2 Spc7 kinetochore protein AAA_29 PF13555.1 EKG13927.1 - 0.0055 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG13927.1 - 0.029 14.5 0.0 0.029 14.5 0.0 4.4 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.22 EKG13927.1 - 0.099 12.9 0.0 0.099 12.9 0.0 7.4 3 2 1 5 5 3 0 ABC transporter Reo_sigmaC PF04582.7 EKG13927.1 - 0.21 10.7 29.8 0.5 9.5 0.3 6.6 3 2 3 7 7 7 0 Reovirus sigma C capsid protein Cellulase PF00150.13 EKG13928.1 - 5.4e-18 65.1 8.3 1.1e-17 64.2 5.8 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) LGFP PF08310.6 EKG13928.1 - 0.0069 16.0 2.5 0.071 12.7 0.1 3.1 3 0 0 3 3 3 1 LGFP repeat Epimerase PF01370.16 EKG13929.1 - 1.1e-23 83.8 0.0 1.4e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG13929.1 - 2.8e-10 39.3 0.0 3.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EKG13929.1 - 3.1e-10 39.4 0.0 4e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EKG13929.1 - 6e-10 38.4 0.0 6e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EKG13929.1 - 1.8e-09 37.7 0.3 4.9e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EKG13929.1 - 1.2e-07 31.9 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG13929.1 - 0.00057 19.6 0.1 0.0014 18.3 0.0 1.8 1 1 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EKG13929.1 - 0.0049 16.6 0.0 0.0081 15.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF1537 PF07005.6 EKG13930.1 - 5e-23 81.9 4.9 5e-23 81.9 3.4 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 Rhodanese PF00581.15 EKG13931.1 - 1.2e-13 51.4 0.0 3.7e-13 49.8 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain BTB PF00651.26 EKG13932.1 - 1.2e-08 34.9 0.1 5e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EKG13932.1 - 0.098 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Fasciclin PF02469.17 EKG13934.1 - 6.4e-16 58.5 0.0 8.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Nucleopor_Nup85 PF07575.8 EKG13936.1 - 2.4e-26 92.1 0.0 8.6e-25 86.9 0.0 2.7 1 1 0 1 1 1 1 Nup85 Nucleoporin Kelch_3 PF13415.1 EKG13938.1 - 4e-31 106.4 7.0 9.1e-06 25.6 0.0 6.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EKG13938.1 - 6.2e-29 99.5 5.2 1.3e-12 47.2 0.0 7.2 6 2 1 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EKG13938.1 - 1.1e-16 60.1 0.2 0.04 14.1 0.0 6.6 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.1 EKG13938.1 - 1.5e-14 53.5 0.1 0.036 14.0 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EKG13938.1 - 3.2e-14 52.2 0.0 0.017 14.6 0.0 6.5 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EKG13938.1 - 1.2e-06 28.0 5.8 1.4 8.7 0.1 5.4 5 1 0 5 5 5 3 Kelch motif Tymo_coat PF00983.13 EKG13938.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Tymovirus coat protein Glyco_hydro_18 PF00704.23 EKG13939.1 - 5.1e-07 29.4 0.0 6.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.11 EKG13941.1 - 3e-35 121.5 37.8 3e-35 121.5 26.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RanBP PF00641.13 EKG13941.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Mtf2_C PF14061.1 EKG13942.1 - 0.031 14.1 0.1 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Ras PF00071.17 EKG13943.1 - 9.4e-42 142.1 0.0 1.2e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG13943.1 - 2.3e-13 50.6 0.0 3.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG13943.1 - 2e-10 40.1 0.0 6.5e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG13943.1 - 0.00039 19.8 0.0 0.001 18.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKG13943.1 - 0.0007 19.0 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EKG13943.1 - 0.0031 16.6 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EKG13943.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 1.9 2 1 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 EKG13943.1 - 0.0039 17.1 0.0 0.0057 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKG13943.1 - 0.0061 15.7 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EKG13943.1 - 0.0069 16.1 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EKG13943.1 - 0.011 15.3 0.0 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EKG13943.1 - 0.013 15.5 0.0 0.051 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EKG13943.1 - 0.016 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EKG13943.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKG13943.1 - 0.03 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EKG13943.1 - 0.032 14.4 0.0 0.076 13.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EKG13943.1 - 0.036 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKG13943.1 - 0.056 13.3 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain PAF-AH_p_II PF03403.8 EKG13944.1 - 4.8e-37 127.1 0.0 1.4e-36 125.6 0.0 1.6 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EKG13944.1 - 5.4e-08 32.7 0.1 1.3e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EKG13944.1 - 2e-06 26.8 0.0 3.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EKG13944.1 - 4.5e-06 25.6 0.0 7.1e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 EKG13944.1 - 0.00043 20.2 0.1 0.00098 19.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG13944.1 - 0.0066 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase SH3_2 PF07653.12 EKG13944.1 - 0.016 14.7 0.1 0.075 12.5 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain DLH PF01738.13 EKG13944.1 - 0.097 11.9 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family FRG1 PF06229.7 EKG13946.1 - 1.9e-57 193.8 0.3 3.2e-57 193.0 0.2 1.4 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EKG13946.1 - 0.002 18.1 0.0 0.1 12.7 0.0 2.7 2 1 0 2 2 2 1 Fascin domain DUF4540 PF15073.1 EKG13947.1 - 0.17 12.4 0.8 0.29 11.6 0.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4540) Pox_A21 PF05323.7 EKG13947.1 - 2.1 8.7 4.1 0.98 9.8 1.3 1.6 1 1 1 2 2 2 0 Poxvirus A21 Protein FPN1 PF06963.7 EKG13948.1 - 1.8e-85 286.9 8.6 2.4e-85 286.5 6.0 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) NMO PF03060.10 EKG13949.1 - 1.2e-35 123.2 9.4 1.3e-27 96.8 2.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 EKG13949.1 - 0.00015 20.7 1.0 0.00091 18.2 1.5 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EKG13949.1 - 0.00035 19.5 4.4 0.00055 18.8 3.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EKG13949.1 - 0.0042 16.0 0.3 0.0064 15.4 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase PcrB PF01884.12 EKG13949.1 - 0.14 11.3 0.2 0.21 10.7 0.2 1.2 1 0 0 1 1 1 0 PcrB family DUF4131 PF13567.1 EKG13950.1 - 0.00095 18.6 6.0 0.057 12.8 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) Cytochrom_B561 PF03188.11 EKG13950.1 - 0.00099 18.9 7.7 0.00099 18.9 5.3 2.2 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EKG13950.1 - 0.029 13.9 1.5 0.064 12.8 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Hormone_2 PF00123.15 EKG13950.1 - 0.06 13.2 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 Peptide hormone DUF998 PF06197.8 EKG13950.1 - 0.079 12.2 25.1 0.18 11.1 9.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF998) DUF3318 PF11780.3 EKG13950.1 - 9 5.8 8.8 6.4 6.3 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3318) Fungal_trans PF04082.13 EKG13951.1 - 8.7e-12 44.4 3.6 1.3e-11 43.8 2.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG13951.1 - 7.2e-10 38.6 9.4 1.1e-09 37.9 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_4 PF12799.2 EKG13952.1 - 4.4e-05 22.9 2.0 0.39 10.3 0.1 3.9 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EKG13952.1 - 0.28 11.5 5.6 5.6 7.6 0.3 4.5 5 0 0 5 5 5 0 Leucine rich repeat SPX PF03105.14 EKG13955.1 - 2.6e-07 30.6 0.2 9.6e-07 28.8 0.0 1.6 1 1 1 2 2 2 1 SPX domain Tropomyosin_1 PF12718.2 EKG13955.1 - 8e-05 22.5 8.5 8e-05 22.5 5.9 2.3 2 0 0 2 2 2 1 Tropomyosin like IncA PF04156.9 EKG13955.1 - 0.00027 20.5 13.9 0.014 15.0 8.7 2.3 2 0 0 2 2 2 1 IncA protein TMF_DNA_bd PF12329.3 EKG13955.1 - 0.0019 17.9 16.9 0.68 9.7 3.4 3.1 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding Filament PF00038.16 EKG13955.1 - 0.0036 16.8 19.5 0.18 11.2 1.5 2.2 2 0 0 2 2 2 2 Intermediate filament protein GAS PF13851.1 EKG13955.1 - 0.023 13.8 13.8 0.065 12.4 6.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EKG13955.1 - 0.062 13.1 19.5 0.078 12.7 6.2 2.5 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EKG13955.1 - 0.068 12.3 3.5 0.31 10.1 0.4 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 EKG13955.1 - 0.084 12.3 14.7 0.075 12.4 6.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) AKNA PF12443.3 EKG13955.1 - 0.099 12.6 6.2 9.2 6.3 0.0 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor DUF2730 PF10805.3 EKG13955.1 - 0.1 12.3 11.5 0.18 11.5 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) MbeD_MobD PF04899.7 EKG13955.1 - 0.12 12.2 6.4 1.4 8.9 1.4 2.7 2 1 0 2 2 2 0 MbeD/MobD like V_ATPase_I PF01496.14 EKG13955.1 - 0.14 10.0 7.9 0.53 8.0 4.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Nsp1_C PF05064.8 EKG13955.1 - 0.18 11.4 5.6 5.2 6.7 1.7 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region TPR_MLP1_2 PF07926.7 EKG13955.1 - 0.34 10.6 19.3 0.46 10.2 6.9 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.9 EKG13955.1 - 0.45 10.1 12.4 3.4 7.2 4.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALCOCO1 PF07888.6 EKG13955.1 - 0.45 8.7 15.5 2 6.6 5.9 2.6 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6 PF04111.7 EKG13955.1 - 0.69 8.8 15.0 0.44 9.5 6.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 NPV_P10 PF05531.7 EKG13955.1 - 0.99 9.7 9.2 4.8 7.4 0.4 4.0 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EKG13955.1 - 1.1 7.8 14.3 0.27 9.8 5.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EKG13955.1 - 1.2 9.1 12.7 7.5 6.6 0.5 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 EKG13955.1 - 1.2 8.8 13.6 0.86 9.3 1.8 2.7 3 0 0 3 3 2 0 Laminin Domain II Macoilin PF09726.4 EKG13955.1 - 1.4 7.1 8.0 0.66 8.1 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein DivIC PF04977.10 EKG13955.1 - 1.8 8.1 21.8 0.83 9.1 0.5 3.6 3 1 1 4 4 3 0 Septum formation initiator Sec34 PF04136.10 EKG13955.1 - 2.1 8.0 5.9 0.99 9.0 1.5 2.2 2 1 1 3 3 3 0 Sec34-like family Med9 PF07544.8 EKG13955.1 - 2.2 8.0 11.0 2.5 7.8 3.4 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_13 PF13166.1 EKG13955.1 - 2.2 6.6 9.8 0.25 9.7 2.8 1.9 2 0 0 2 2 2 0 AAA domain Tnp_P_element PF12017.3 EKG13955.1 - 2.4 7.3 6.1 12 5.0 0.8 2.3 2 0 0 2 2 2 0 Transposase protein UBA PF00627.26 EKG13955.1 - 2.8 7.9 6.5 8.4 6.3 0.4 3.2 3 0 0 3 3 2 0 UBA/TS-N domain CENP-F_leu_zip PF10473.4 EKG13955.1 - 3 7.7 18.7 29 4.5 9.1 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 EKG13955.1 - 3.1 7.7 8.6 2.7 7.9 1.8 3.1 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) HALZ PF02183.13 EKG13955.1 - 3.1 7.5 9.9 2.3 8.0 0.3 4.1 3 1 1 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 EKG13955.1 - 3.1 7.8 8.3 34 4.5 2.5 3.3 2 1 1 3 3 3 0 bZIP transcription factor Fib_alpha PF08702.5 EKG13955.1 - 3.3 7.8 9.1 30 4.7 3.9 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TBPIP PF07106.8 EKG13955.1 - 3.5 7.1 13.0 13 5.2 4.3 2.7 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc24 PF08286.6 EKG13955.1 - 3.8 7.2 15.5 0.98 9.1 3.6 3.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 EKG13955.1 - 4.9 7.5 11.4 33 4.8 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) HCMV_UL139 PF12507.3 EKG13955.1 - 5.8 7.1 9.1 4.7 7.3 1.9 2.4 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein Cortex-I_coil PF09304.5 EKG13955.1 - 7.7 6.6 14.4 0.29 11.1 3.3 2.9 3 1 0 3 3 2 0 Cortexillin I, coiled coil Spectrin PF00435.16 EKG13955.1 - 7.8 6.8 14.8 14 6.0 0.3 2.9 2 1 0 2 2 2 0 Spectrin repeat DUF1664 PF07889.7 EKG13955.1 - 8.1 6.2 7.0 32 4.3 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 EKG13955.1 - 8.2 6.6 13.2 14 5.8 3.3 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ADIP PF11559.3 EKG13955.1 - 8.6 6.2 17.6 3.7 7.4 6.8 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Glucosamine_iso PF01182.15 EKG13956.1 - 1.8e-57 194.2 0.0 2.2e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SET PF00856.23 EKG13958.1 - 1.1e-07 32.2 0.0 2e-06 28.2 0.0 2.6 2 1 0 2 2 2 1 SET domain GMC_oxred_C PF05199.8 EKG13959.1 - 3.8e-31 108.3 0.0 6.3e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EKG13959.1 - 8.8e-23 80.8 0.0 2.5e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase S1-P1_nuclease PF02265.11 EKG13963.1 - 5.3e-56 190.0 0.0 6.2e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Asp PF00026.18 EKG13964.1 - 3.5e-69 233.4 1.6 4.4e-69 233.1 1.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKG13964.1 - 3.8e-11 43.2 0.0 1.5e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EKG13964.1 - 0.0017 18.8 6.1 0.14 12.6 0.3 4.3 3 2 1 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 EKG13964.1 - 0.0093 15.5 0.0 0.062 12.8 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Hydantoinase_B PF02538.9 EKG13965.1 - 3.6e-173 576.5 0.0 5e-173 576.1 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EKG13965.1 - 1.3e-92 310.0 0.6 5.8e-91 304.6 0.0 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EKG13965.1 - 9.2e-56 188.1 2.8 4.9e-55 185.7 0.0 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region HTH_11 PF08279.7 EKG13965.1 - 0.051 13.2 0.1 0.54 9.9 0.0 2.5 2 0 0 2 2 2 0 HTH domain KorB PF08535.5 EKG13965.1 - 0.2 11.8 0.9 1 9.5 0.0 2.8 3 0 0 3 3 3 0 KorB domain MFS_1 PF07690.11 EKG13966.1 - 6.7e-28 97.4 32.6 1.2e-27 96.5 22.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUP PF00674.13 EKG13966.1 - 0.016 15.1 0.2 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 DUP family DUF3278 PF11683.3 EKG13966.1 - 0.21 11.5 3.3 0.36 10.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF1228 PF06779.9 EKG13966.1 - 0.89 9.6 13.6 0.25 11.3 1.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF485 PF04341.7 EKG13966.1 - 4.5 7.0 9.0 0.6 9.8 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Fungal_trans_2 PF11951.3 EKG13967.1 - 2.3e-60 204.2 0.5 2.7e-60 203.9 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu-oxidase_3 PF07732.10 EKG13968.1 - 1.6e-42 143.9 0.5 1.6e-42 143.9 0.4 2.6 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG13968.1 - 9.9e-38 128.7 6.0 4.2e-31 107.3 0.1 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG13968.1 - 1.4e-34 119.2 0.3 7.6e-32 110.4 0.0 2.6 2 1 0 2 2 2 2 Multicopper oxidase TadE PF07811.7 EKG13968.1 - 0.52 10.2 3.0 0.23 11.3 0.2 1.9 2 0 0 2 2 2 0 TadE-like protein Phosphoesterase PF04185.9 EKG13969.1 - 5.7e-35 121.2 0.7 1.5e-34 119.8 0.3 1.7 1 1 1 2 2 2 1 Phosphoesterase family GST_N PF02798.15 EKG13970.1 - 1.5e-14 53.9 0.0 2.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EKG13970.1 - 2.4e-12 46.6 0.4 4.1e-12 45.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG13970.1 - 8.7e-09 35.4 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG13970.1 - 1.1e-07 31.5 0.1 2e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG13970.1 - 1.9e-06 27.7 0.0 3.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG13970.1 - 8.6e-06 26.1 0.2 1.4e-05 25.4 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FSH1 PF03959.8 EKG13971.1 - 4.9e-34 117.6 0.0 5.6e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EKG13971.1 - 7.5e-07 29.2 2.2 0.00033 20.6 0.2 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG13971.1 - 0.0046 16.7 0.0 0.0088 15.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2235 PF09994.4 EKG13971.1 - 0.069 12.5 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_2 PF02230.11 EKG13971.1 - 0.088 12.2 0.3 0.31 10.4 0.2 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Aldedh PF00171.17 EKG13973.1 - 6.7e-48 163.1 0.3 8.1e-48 162.9 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Epimerase PF01370.16 EKG13975.1 - 4.5e-11 42.6 0.1 4.3e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG13975.1 - 2.6e-08 32.9 0.0 0.0025 16.5 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EKG13975.1 - 1e-07 32.2 0.0 2.6e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EKG13975.1 - 0.00023 20.5 0.1 0.00034 19.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 EKG13975.1 - 0.014 15.4 0.0 0.74 9.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EKG13975.1 - 0.015 14.1 0.1 0.075 11.9 0.0 2.2 2 1 0 2 2 2 0 Male sterility protein Saccharop_dh PF03435.13 EKG13975.1 - 0.017 14.1 0.1 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase GFO_IDH_MocA PF01408.17 EKG13975.1 - 0.052 14.0 0.0 0.22 12.0 0.0 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EKG13975.1 - 0.12 12.3 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_3 PF01494.14 EKG13976.1 - 1e-91 307.6 0.0 1.3e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG13976.1 - 0.00015 21.7 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG13976.1 - 0.00079 18.4 0.1 0.059 12.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG13976.1 - 0.0078 15.0 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG13976.1 - 0.013 15.5 2.1 0.014 15.4 0.2 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG13976.1 - 0.052 13.9 0.0 5 7.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG13976.1 - 0.098 12.7 1.0 0.3 11.1 0.7 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EKG13976.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EKG13976.1 - 0.16 10.8 0.8 0.49 9.2 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein EF-hand_6 PF13405.1 EKG13979.1 - 1.5e-10 39.9 0.2 0.0003 20.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EKG13979.1 - 8.3e-09 34.1 0.2 0.0032 16.6 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EKG13979.1 - 3.1e-08 33.6 0.5 3.3e-05 23.9 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EKG13979.1 - 7.8e-06 25.0 0.6 0.021 14.1 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EKG13979.1 - 0.0016 18.0 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EKG13979.1 - 0.0075 16.1 0.0 1.1 9.2 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain Afi1 PF07792.7 EKG13980.1 - 2.5e-62 209.1 0.0 4.1e-62 208.4 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EKG13980.1 - 1.8e-36 124.2 0.0 3e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EKG13980.1 - 2e-07 29.8 0.0 0.065 11.7 0.0 3.8 3 1 1 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EKG13980.1 - 0.0037 16.5 0.0 0.021 14.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Nop25 PF09805.4 EKG13980.1 - 0.0042 17.1 11.1 0.0069 16.4 7.7 1.3 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Peripla_BP_6 PF13458.1 EKG13980.1 - 0.019 14.3 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 0 Periplasmic binding protein DUF1168 PF06658.7 EKG13980.1 - 0.043 13.3 9.1 0.08 12.4 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Ycf1 PF05758.7 EKG13980.1 - 0.22 9.2 0.9 0.29 8.8 0.6 1.1 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 EKG13980.1 - 0.67 8.7 4.9 1 8.1 3.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Cwf_Cwc_15 PF04889.7 EKG13980.1 - 0.93 9.1 14.5 1.5 8.4 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.5 EKG13980.1 - 1.1 9.2 5.8 2.2 8.2 4.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 EKG13980.1 - 1.5 8.1 9.1 2.4 7.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIA PF03153.8 EKG13980.1 - 2.6 7.8 8.1 5.3 6.8 5.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EKG13980.1 - 3.1 5.5 13.5 4.7 4.9 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EKG13980.1 - 5.3 5.2 15.7 7.6 4.7 10.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PH PF00169.24 EKG13981.1 - 4.7e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EKG13981.1 - 0.0016 18.6 0.0 0.0044 17.1 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain SSP160 PF06933.6 EKG13981.1 - 0.082 10.8 16.4 0.13 10.2 11.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EKG13981.1 - 0.33 10.6 10.6 0.7 9.6 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_11 PF13414.1 EKG13986.1 - 6.3e-05 22.5 4.8 0.065 12.8 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EKG13986.1 - 0.017 15.2 0.7 1.2 9.5 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKG13986.1 - 0.14 12.8 15.5 2.9 8.6 2.4 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG13986.1 - 1.9 9.3 9.8 2.3 9.0 0.2 5.3 3 2 3 6 6 6 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 EKG13987.1 - 9.6e-12 44.7 0.0 1.5e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKG13987.1 - 1.8e-05 24.4 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EKG13987.1 - 0.001 18.9 0.0 0.0013 18.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG13987.1 - 0.0037 17.3 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG13987.1 - 0.0058 16.7 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG13987.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF918 PF06033.6 EKG13987.1 - 0.13 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) PAS_9 PF13426.1 EKG13988.1 - 3.9e-16 59.3 0.0 9.5e-16 58.0 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EKG13988.1 - 0.00028 20.6 1.2 0.0022 17.7 0.0 2.7 3 0 0 3 3 3 1 PAS fold PQ-loop PF04193.9 EKG13989.1 - 1e-34 117.8 15.5 6.6e-19 67.2 0.2 3.3 3 0 0 3 3 3 2 PQ loop repeat zf-HC5HC2H_2 PF13832.1 EKG13990.1 - 2.6e-33 114.2 7.1 2.6e-33 114.2 4.9 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EKG13990.1 - 2e-27 95.1 5.6 2e-27 95.1 3.9 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EKG13990.1 - 2.2e-26 93.0 0.0 6.5e-26 91.4 0.0 1.9 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EKG13990.1 - 2.9e-14 52.0 2.1 2.9e-14 52.0 1.4 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EKG13990.1 - 1.3e-08 34.4 24.2 1.1e-07 31.4 6.8 2.8 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 EKG13990.1 - 0.57 10.2 20.1 0.037 14.0 3.3 2.9 2 1 0 2 2 2 0 RING-like domain RRM_1 PF00076.17 EKG13991.1 - 1.1e-20 73.0 0.0 1.5e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG13991.1 - 4.9e-17 61.6 0.0 7.5e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG13991.1 - 4e-13 49.0 0.0 5.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3431 PF11913.3 EKG13992.1 - 1.4e-88 296.1 0.1 1.8e-88 295.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) LisH PF08513.6 EKG13995.1 - 0.00062 19.4 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EKG13995.1 - 0.004 16.9 2.9 13 5.8 0.0 4.8 5 1 0 5 5 5 2 WD domain, G-beta repeat FRG2 PF15315.1 EKG13995.1 - 0.46 10.4 2.0 0.69 9.8 1.4 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Glyoxalase_3 PF13468.1 EKG13997.1 - 5.3e-28 98.0 0.2 7.5e-28 97.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain DUF221 PF02714.10 EKG13998.1 - 2.1e-92 309.4 12.4 3.7e-92 308.6 8.6 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EKG13998.1 - 1.3e-43 148.2 1.5 1.3e-43 148.2 1.1 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EKG13998.1 - 5.1e-19 68.5 0.1 1.1e-18 67.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EKG13998.1 - 0.00056 18.6 0.1 0.0014 17.3 0.1 1.7 1 0 0 1 1 1 1 Calcium-activated chloride channel RRM_6 PF14259.1 EKG13998.1 - 0.0032 17.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) TatD_DNase PF01026.16 EKG13999.1 - 3.5e-31 108.3 0.0 5.5e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase MAGE_N PF12440.3 EKG13999.1 - 0.12 12.6 0.7 0.26 11.5 0.5 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal DUF883 PF05957.8 EKG14002.1 - 0.03 14.7 4.3 0.21 11.9 2.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Spo7 PF03907.8 EKG14003.1 - 2.1e-73 246.4 0.0 2.7e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Zip PF02535.17 EKG14003.1 - 2.4 7.0 6.1 3.7 6.4 4.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EKG14003.1 - 6.3 4.9 15.6 9.3 4.3 10.8 1.2 1 0 0 1 1 1 0 Transmembrane protein TPP_enzyme_N PF02776.13 EKG14004.1 - 3.7e-36 124.1 0.0 2.4e-35 121.5 0.0 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Abhydrolase_6 PF12697.2 EKG14004.1 - 6.6e-28 98.1 0.8 2.4e-26 93.0 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family TPP_enzyme_M PF00205.17 EKG14004.1 - 4.5e-21 75.0 0.0 1e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EKG14004.1 - 1e-18 67.3 0.0 2.8e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Abhydrolase_1 PF00561.15 EKG14004.1 - 1.8e-15 57.1 0.0 4.9e-14 52.4 0.0 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG14004.1 - 7.7e-13 48.4 0.0 2.9e-10 40.0 0.0 3.1 3 0 0 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.15 EKG14004.1 - 0.00023 20.6 0.0 0.00047 19.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EKG14004.1 - 0.00028 20.0 0.0 0.00074 18.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) NTP_transf_3 PF12804.2 EKG14004.1 - 0.007 16.4 0.2 2.6 8.0 0.1 2.6 1 1 1 2 2 2 1 MobA-like NTP transferase domain Lipase_3 PF01764.20 EKG14004.1 - 0.054 13.0 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.3 EKG14004.1 - 0.056 13.2 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase Thioesterase PF00975.15 EKG14004.1 - 0.066 13.4 4.9 0.072 13.2 0.3 2.7 2 1 0 2 2 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EKG14004.1 - 0.076 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EKG14004.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF1824 PF08854.5 EKG14005.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Glyco_tranf_2_3 PF13641.1 EKG14006.1 - 3.7e-16 59.6 0.0 5.1e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EKG14006.1 - 3.9e-08 32.7 0.0 4.4e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EKG14006.1 - 1.1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 F5_F8_type_C PF00754.20 EKG14007.1 - 9e-12 44.9 0.1 1.2e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain Amidase_5 PF05382.8 EKG14008.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase G-alpha PF00503.15 EKG14010.1 - 1.1e-128 429.3 0.1 1.3e-128 429.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EKG14010.1 - 5.8e-16 58.2 0.7 6.6e-11 41.7 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG14010.1 - 8.9e-05 21.7 0.1 0.31 10.1 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EKG14010.1 - 0.0011 19.4 0.1 0.5 10.8 0.0 2.6 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EKG14010.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EKG14010.1 - 0.095 12.1 0.0 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 EKG14011.1 - 5.1e-72 242.1 0.0 6.2e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG14011.1 - 3.2e-31 108.3 0.0 4.2e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKG14011.1 - 1.8e-05 23.8 0.0 6.2e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKG14011.1 - 0.00028 19.9 0.0 0.027 13.4 0.0 2.2 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 EKG14011.1 - 0.00036 20.3 0.0 0.001 18.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKG14011.1 - 0.026 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pirin PF02678.11 EKG14012.1 - 9.7e-26 89.7 1.0 1.7e-25 88.9 0.7 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EKG14012.1 - 0.0016 17.8 0.6 0.0016 17.8 0.4 2.7 3 0 0 3 3 3 1 Cupin domain Cellulase PF00150.13 EKG14013.1 - 3.1e-29 102.0 5.3 4.8e-29 101.4 3.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PMEI PF04043.10 EKG14014.1 - 3.3 7.6 11.3 0.03 14.2 0.8 2.6 3 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor PPR_2 PF13041.1 EKG14015.1 - 2.7e-25 88.0 0.4 3.4e-08 33.3 0.0 8.0 8 1 1 9 9 9 3 PPR repeat family PPR_3 PF13812.1 EKG14015.1 - 1.5e-21 74.7 12.9 0.0087 16.2 0.0 12.0 13 0 0 13 13 13 5 Pentatricopeptide repeat domain PPR PF01535.15 EKG14015.1 - 1.8e-18 65.1 1.4 0.0045 16.8 0.0 10.1 11 0 0 11 11 11 3 PPR repeat PPR_1 PF12854.2 EKG14015.1 - 1.6e-11 43.4 0.0 0.0047 16.3 0.0 5.3 6 0 0 6 6 6 3 PPR repeat TPR_16 PF13432.1 EKG14015.1 - 1.3e-05 25.7 4.4 0.0042 17.7 0.1 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG14015.1 - 0.0099 16.2 11.4 1.1 9.6 0.1 5.3 6 1 1 7 7 7 2 Tetratricopeptide repeat Rhabdo_ncap_2 PF03216.8 EKG14015.1 - 0.037 12.7 0.0 0.069 11.8 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleoprotein TPR_4 PF07721.9 EKG14015.1 - 0.05 14.0 1.4 6.8 7.4 0.0 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Retrotrans_gag PF03732.12 EKG14015.1 - 0.12 12.4 2.5 18 5.5 0.1 3.4 3 0 0 3 3 3 0 Retrotransposon gag protein TPR_14 PF13428.1 EKG14015.1 - 0.39 11.4 15.9 5.2 7.9 0.0 7.7 8 2 1 9 9 9 0 Tetratricopeptide repeat Glyco_hydro_45 PF02015.11 EKG14016.1 - 5.8e-80 268.0 19.7 6.6e-80 267.9 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Sugar_tr PF00083.19 EKG14017.1 - 4.5e-120 401.2 21.2 7.2e-120 400.6 14.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG14017.1 - 3.5e-21 75.3 47.9 9.1e-11 41.0 12.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_53 PF07745.8 EKG14018.1 - 1.3e-101 339.7 0.0 1.4e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 CorA PF01544.13 EKG14019.1 - 0.0019 17.2 0.0 0.0048 15.9 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 EKG14020.1 - 5.9e-24 84.4 54.2 2.8e-12 46.0 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Internalin_N PF12354.3 EKG14020.1 - 0.1 12.2 0.3 5.8 6.6 0.0 3.1 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Amino_oxidase PF01593.19 EKG14021.1 - 6.2e-64 216.7 0.3 9e-64 216.1 0.2 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKG14021.1 - 2.1e-12 46.8 0.2 4.5e-12 45.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG14021.1 - 4.6e-11 42.2 0.3 3.7e-07 29.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG14021.1 - 1.8e-07 30.4 0.5 3.7e-07 29.3 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EKG14021.1 - 2.3e-06 27.8 0.0 0.00036 20.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG14021.1 - 4.5e-06 26.5 1.1 0.03 14.1 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EKG14021.1 - 5.6e-06 25.0 0.0 0.00017 20.1 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EKG14021.1 - 1e-05 25.8 0.6 3e-05 24.3 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG14021.1 - 4.3e-05 22.7 1.0 8.4e-05 21.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EKG14021.1 - 0.00013 21.0 1.4 0.054 12.3 0.6 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 EKG14021.1 - 0.00021 20.4 0.4 0.00038 19.6 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EKG14021.1 - 0.00032 20.6 0.3 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG14021.1 - 0.0014 17.8 0.3 0.0023 17.1 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase F420_oxidored PF03807.12 EKG14021.1 - 0.076 13.4 0.9 0.55 10.6 0.3 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EKG14021.1 - 0.13 11.9 0.4 0.24 11.0 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 EKG14021.1 - 0.14 10.2 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like DUF3929 PF13066.1 EKG14021.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) Acyl_transf_3 PF01757.17 EKG14022.1 - 3.5e-07 29.3 8.6 4.4e-07 29.0 6.0 1.1 1 0 0 1 1 1 1 Acyltransferase family Thiolase_N PF00108.18 EKG14024.1 - 4.9e-56 189.6 0.4 1.1e-55 188.5 0.3 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EKG14024.1 - 3e-41 139.7 0.2 3e-41 139.7 0.1 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EKG14024.1 - 0.0021 17.6 0.0 0.6 9.8 0.0 2.3 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EKG14025.1 - 2.2e-07 30.1 0.0 2.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain MFS_1 PF07690.11 EKG14026.1 - 6.9e-36 123.6 30.3 6.9e-36 123.6 21.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG14026.1 - 2.6e-05 22.6 3.3 2.6e-05 22.6 2.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TMEM169 PF15052.1 EKG14026.1 - 0.082 12.8 1.1 0.49 10.3 0.5 2.3 2 0 0 2 2 2 0 TMEM169 protein family Amidohydro_3 PF07969.6 EKG14027.1 - 5.9e-56 190.4 13.4 7.1e-56 190.1 9.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKG14027.1 - 4.7e-10 39.1 0.0 2e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG14027.1 - 8.8e-05 22.3 1.8 0.13 11.9 0.2 3.1 2 1 0 2 2 2 2 Amidohydrolase family Phosphorylase PF00343.15 EKG14028.1 - 0 1077.6 0.0 0 1077.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Cyclin_N PF00134.18 EKG14029.1 - 0.0096 15.4 0.0 0.021 14.3 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain UPF0121 PF03661.8 EKG14031.1 - 4.8e-10 39.0 3.0 6.6e-10 38.5 2.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Septin PF00735.13 EKG14032.1 - 1.2e-123 411.6 0.1 1.2e-123 411.6 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EKG14032.1 - 9.3e-07 28.8 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKG14032.1 - 5.1e-05 22.5 0.2 0.00052 19.2 0.2 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKG14032.1 - 9.3e-05 22.7 4.9 0.024 14.9 0.0 2.8 2 1 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EKG14032.1 - 0.00034 20.1 2.0 0.0013 18.2 0.1 2.3 1 1 0 2 2 2 1 AAA-like domain Ras PF00071.17 EKG14032.1 - 0.0013 18.1 1.4 0.026 13.9 0.0 3.0 2 1 0 2 2 2 1 Ras family Dynamin_N PF00350.18 EKG14032.1 - 0.0016 18.2 6.6 0.54 10.0 0.0 4.2 4 1 0 4 4 3 1 Dynamin family GTP_EFTU PF00009.22 EKG14032.1 - 0.0021 17.5 2.8 0.012 14.9 0.0 3.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EKG14032.1 - 0.0022 18.4 0.9 0.0085 16.5 0.0 2.4 3 0 0 3 3 2 1 Miro-like protein AAA_16 PF13191.1 EKG14032.1 - 0.0026 17.7 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG14032.1 - 0.003 17.6 0.1 0.023 14.8 0.0 2.5 2 2 0 2 2 2 1 AAA domain AIG1 PF04548.11 EKG14032.1 - 0.0035 16.4 0.0 0.0035 16.4 0.0 2.4 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.1 EKG14032.1 - 0.0073 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EKG14032.1 - 0.012 15.1 1.2 0.021 14.3 0.0 2.0 2 0 0 2 2 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EKG14032.1 - 0.012 15.7 0.8 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.1 EKG14032.1 - 0.012 14.2 10.2 0.34 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain YlqD PF11068.3 EKG14032.1 - 0.027 14.5 13.2 0.051 13.6 9.2 1.5 1 0 0 1 1 1 0 YlqD protein ATP_bind_1 PF03029.12 EKG14032.1 - 0.029 13.9 0.4 4 6.9 0.0 3.0 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 EKG14032.1 - 0.042 13.0 7.6 0.082 12.0 5.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit MobB PF03205.9 EKG14032.1 - 0.13 11.9 1.5 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EKG14032.1 - 0.16 11.5 1.8 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EKG14032.1 - 0.4 10.4 5.1 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Phage_GPO PF05929.6 EKG14032.1 - 0.59 9.3 7.4 0.98 8.6 5.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 EKG14032.1 - 0.63 9.6 11.9 1 8.9 8.2 1.3 1 0 0 1 1 1 0 IncA protein DUF2937 PF11157.3 EKG14032.1 - 1.7 7.9 3.7 3.4 6.9 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) V_ATPase_I PF01496.14 EKG14032.1 - 3.8 5.2 11.4 5.7 4.6 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exo70 PF03081.10 EKG14033.1 - 1.3e-78 264.3 0.5 7e-78 262.0 0.0 2.1 2 1 0 2 2 2 1 Exo70 exocyst complex subunit NPV_P10 PF05531.7 EKG14033.1 - 0.2 11.9 5.6 20 5.4 0.1 4.5 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein COG5 PF10392.4 EKG14033.1 - 0.22 11.5 3.9 0.72 9.8 0.0 3.5 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Apolipoprotein PF01442.13 EKG14033.1 - 0.25 10.8 2.6 7.9 5.9 0.0 3.5 4 0 0 4 4 4 0 Apolipoprotein A1/A4/E domain Syntaxin-6_N PF09177.6 EKG14033.1 - 0.76 10.2 7.6 10 6.5 0.1 5.0 6 0 0 6 6 6 0 Syntaxin 6, N-terminal DUF2935 PF11155.3 EKG14033.1 - 0.94 9.5 4.4 4.3 7.4 0.0 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) PLA2_B PF01735.13 EKG14034.1 - 1.8e-22 79.2 0.0 3.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PLDc PF00614.17 EKG14035.1 - 3.6e-13 48.8 4.2 1.1e-06 28.1 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EKG14035.1 - 7.5e-11 41.8 0.0 4.1e-05 23.3 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain Aminotran_5 PF00266.14 EKG14036.1 - 5.2e-55 186.6 0.0 6.4e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EKG14036.1 - 8.1e-05 21.0 0.0 0.00014 20.2 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EKG14036.1 - 0.012 14.5 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class I and II Spc97_Spc98 PF04130.8 EKG14037.1 - 1.8e-62 211.4 0.0 2.7e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family GlutR_N PF05201.10 EKG14037.1 - 0.02 14.4 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain adh_short PF00106.20 EKG14038.1 - 4.9e-21 75.3 0.1 7.9e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG14038.1 - 2.9e-11 43.6 0.5 3.6e-11 43.2 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG14038.1 - 3.4e-10 39.8 0.0 4.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG14038.1 - 1.1e-06 28.2 0.1 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG14038.1 - 0.028 13.3 0.1 0.038 12.9 0.1 1.3 1 0 0 1 1 1 0 Male sterility protein Peripla_BP_4 PF13407.1 EKG14038.1 - 0.033 13.5 0.1 0.048 13.0 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain AIRC PF00731.15 EKG14038.1 - 0.1 11.9 0.1 1.1 8.4 0.0 2.5 1 1 1 3 3 3 0 AIR carboxylase GMC_oxred_C PF05199.8 EKG14039.1 - 1.6e-37 129.0 0.2 2.7e-37 128.2 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EKG14039.1 - 4.7e-34 117.9 0.0 6.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Cu-oxidase_3 PF07732.10 EKG14040.1 - 1.1e-41 141.3 0.3 1.1e-41 141.3 0.2 3.0 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EKG14040.1 - 5.7e-38 130.3 1.1 4.6e-35 120.8 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG14040.1 - 8.2e-38 129.0 16.1 1.1e-33 115.6 3.3 4.0 3 1 0 3 3 3 3 Multicopper oxidase MFS_1 PF07690.11 EKG14042.1 - 1.1e-18 67.0 31.0 2.5e-18 65.9 21.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PDR_assoc PF08370.6 EKG14042.1 - 0.0071 15.8 0.1 0.03 13.8 0.0 2.1 1 0 0 1 1 1 1 Plant PDR ABC transporter associated Brevenin PF03032.10 EKG14042.1 - 4.8 7.0 5.1 11 5.9 3.5 1.5 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family SGL PF08450.7 EKG14043.1 - 1.8e-22 79.9 0.2 6.8e-21 74.7 0.2 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EKG14043.1 - 0.00035 20.5 0.0 0.001 19.0 0.0 1.8 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EKG14043.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Arylesterase NHL PF01436.16 EKG14043.1 - 0.23 11.4 0.0 0.23 11.4 0.0 3.6 4 0 0 4 4 4 0 NHL repeat ADH_zinc_N PF00107.21 EKG14044.1 - 1.1e-13 50.8 0.2 2.1e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG14044.1 - 3.4e-07 30.0 0.1 1.1e-06 28.3 0.1 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EKG14044.1 - 0.00037 21.3 0.2 0.0014 19.5 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sporozoite_P67 PF05642.6 EKG14044.1 - 0.064 11.1 7.8 0.084 10.7 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NPDC1 PF06809.6 EKG14044.1 - 1.8 7.3 7.5 0.67 8.6 3.0 1.5 1 1 1 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) Herpes_capsid PF06112.6 EKG14044.1 - 6 6.9 8.6 11 5.9 6.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MFS_1 PF07690.11 EKG14045.1 - 2e-32 112.2 69.9 7.9e-30 103.7 29.1 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4341 PF14241.1 EKG14045.1 - 0.0065 16.1 2.3 0.0065 16.1 1.6 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF4341) CorA PF01544.13 EKG14045.1 - 8.5 5.3 6.0 0.88 8.5 0.5 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Abhydrolase_6 PF12697.2 EKG14046.1 - 0.00012 22.0 0.4 0.00015 21.7 0.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EKG14047.1 - 6e-17 61.5 0.1 7.9e-17 61.2 0.1 1.1 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG14047.1 - 0.00092 19.1 0.1 0.0011 18.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Herpes_gE PF02480.11 EKG14048.1 - 0.018 13.3 0.0 0.037 12.2 0.0 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E PPR_2 PF13041.1 EKG14049.1 - 7.6e-27 93.0 5.7 0.00037 20.4 0.0 9.6 7 3 4 11 11 11 6 PPR repeat family LSM PF01423.17 EKG14049.1 - 8.3e-14 50.8 0.1 2e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 LSM domain PPR_3 PF13812.1 EKG14049.1 - 3.2e-11 42.5 7.5 0.39 11.1 0.0 8.4 8 0 0 8 8 8 3 Pentatricopeptide repeat domain DSPc PF00782.15 EKG14049.1 - 1.3e-10 40.9 0.0 3.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKG14049.1 - 6.3e-07 28.9 0.0 4.5e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PPR PF01535.15 EKG14049.1 - 8.8e-07 28.4 9.8 0.59 10.2 0.0 8.5 10 0 0 10 10 10 2 PPR repeat PTPlike_phytase PF14566.1 EKG14049.1 - 0.0072 16.3 0.0 0.023 14.7 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate TPR_14 PF13428.1 EKG14049.1 - 0.011 16.3 1.6 27 5.7 0.0 4.8 4 1 0 4 4 3 0 Tetratricopeptide repeat Y_phosphatase3 PF13350.1 EKG14049.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family PTEN_C2 PF10409.4 EKG14049.1 - 0.033 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein PPR_1 PF12854.2 EKG14049.1 - 0.16 11.4 9.1 0.28 10.6 0.0 5.5 8 0 0 8 8 8 0 PPR repeat AAA PF00004.24 EKG14050.1 - 7.9e-18 64.9 0.0 2.1e-16 60.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG14050.1 - 0.00019 22.2 0.0 0.00019 22.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EKG14050.1 - 0.0011 18.6 0.0 0.0032 17.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EKG14050.1 - 0.0096 15.9 1.4 0.027 14.4 0.0 2.4 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EKG14050.1 - 0.014 15.0 0.0 0.048 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG14050.1 - 0.019 15.0 0.8 0.019 15.0 0.5 3.7 4 1 0 4 4 4 0 AAA domain DUF1041 PF06292.12 EKG14050.1 - 0.037 14.2 0.0 0.25 11.5 0.0 2.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Acetyltransf_3 PF13302.1 EKG14051.1 - 4.8e-18 65.6 0.0 7e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG14051.1 - 0.00011 22.2 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG14051.1 - 0.0024 17.8 0.1 0.0052 16.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF1275 PF06912.6 EKG14052.1 - 3.7e-34 117.7 16.4 4.5e-34 117.4 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) La PF05383.12 EKG14053.1 - 7.3e-16 57.7 0.0 1.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EKG14053.1 - 3.6e-08 32.9 0.5 8.4e-08 31.7 0.3 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG14053.1 - 1.2e-07 31.6 0.1 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG14053.1 - 0.0021 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Head_binding PF09008.5 EKG14053.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Head binding S4 PF01479.20 EKG14054.1 - 2.3e-14 52.5 0.0 4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF1664 PF07889.7 EKG14054.1 - 0.0072 16.1 2.5 0.012 15.3 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) S4_2 PF13275.1 EKG14054.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 S4 domain Peptidase_S64 PF08192.6 EKG14054.1 - 0.18 10.1 1.9 0.24 9.7 1.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Herpes_env PF01673.13 EKG14054.1 - 1.1 7.7 3.2 1.6 7.2 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Ycf1 PF05758.7 EKG14054.1 - 2 6.0 6.3 3 5.4 4.4 1.2 1 0 0 1 1 1 0 Ycf1 LMBR1 PF04791.11 EKG14054.1 - 4.3 5.8 4.0 3.8 5.9 1.7 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein HisKA_3 PF07730.8 EKG14054.1 - 7.5 6.9 7.5 23 5.4 0.7 2.7 1 1 1 2 2 2 0 Histidine kinase Abhydrolase_3 PF07859.8 EKG14055.1 - 1.6e-08 34.3 0.0 1.9e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_10 PF05971.7 EKG14056.1 - 6.3e-50 170.0 0.0 3.2e-49 167.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 EKG14056.1 - 4.2e-06 26.2 0.0 7.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EKG14056.1 - 7.3e-05 23.3 0.0 0.00014 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG14056.1 - 0.00026 21.0 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG14056.1 - 0.00062 18.9 0.0 0.00098 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EKG14056.1 - 0.022 14.3 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Kdo_hydroxy PF11004.3 EKG14056.1 - 0.093 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Sirohm_synth_C PF14823.1 EKG14057.1 - 9.8e-31 104.8 0.0 1.4e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EKG14057.1 - 2.7e-15 55.0 0.2 4.1e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.1 EKG14057.1 - 4.8e-12 46.0 0.0 1.4e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FYVE PF01363.16 EKG14058.1 - 7.9e-22 76.9 27.1 3.4e-16 58.8 4.9 2.6 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 EKG14058.1 - 0.00011 21.9 2.7 0.00011 21.9 1.9 3.7 4 1 1 5 5 5 1 AN1-like Zinc finger Rbsn PF11464.3 EKG14058.1 - 0.064 12.8 0.2 0.064 12.8 0.2 2.3 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Allexi_40kDa PF05549.6 EKG14058.1 - 0.62 9.3 5.8 11 5.1 0.0 3.2 3 0 0 3 3 3 0 Allexivirus 40kDa protein CK_II_beta PF01214.13 EKG14058.1 - 2.1 7.8 7.0 0.11 12.0 0.4 2.1 2 0 0 2 2 2 0 Casein kinase II regulatory subunit APG6 PF04111.7 EKG14058.1 - 2.3 7.2 7.2 0.45 9.5 0.5 2.7 3 0 0 3 3 3 0 Autophagy protein Apg6 zinc_ribbon_4 PF13717.1 EKG14058.1 - 2.9 7.6 7.0 18 5.1 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain PH_4 PF15404.1 EKG14060.1 - 1.4e-65 220.2 1.4 1e-63 214.2 0.0 2.8 3 0 0 3 3 3 2 Pleckstrin homology domain PH PF00169.24 EKG14060.1 - 3.9e-09 36.6 0.0 0.00061 19.9 0.0 3.3 2 2 0 2 2 2 2 PH domain PH_6 PF15406.1 EKG14060.1 - 0.0099 15.9 0.1 0.055 13.5 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain Thioredoxin PF00085.15 EKG14062.1 - 2.3e-26 91.5 0.0 3.2e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EKG14062.1 - 2.2e-06 27.8 0.1 1e-05 25.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKG14062.1 - 3.6e-06 26.9 0.0 0.00029 20.8 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EKG14062.1 - 1.6e-05 24.8 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EKG14062.1 - 0.0018 17.8 0.1 0.82 9.2 0.0 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EKG14062.1 - 0.0047 16.6 0.1 0.72 9.5 0.1 2.3 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EKG14062.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HyaE PF07449.6 EKG14062.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Mit_KHE1 PF10173.4 EKG14065.1 - 6e-61 205.5 0.2 6e-61 205.5 0.1 1.9 2 1 0 2 2 2 1 Mitochondrial K+-H+ exchange-related adh_short PF00106.20 EKG14066.1 - 8.1e-23 81.1 0.5 1.1e-22 80.6 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG14066.1 - 2.3e-20 73.3 0.2 3.8e-20 72.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG14066.1 - 7.7e-11 41.9 0.4 1.1e-10 41.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG14066.1 - 2e-06 27.4 0.1 2.8e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG14066.1 - 0.00044 19.9 0.2 0.00094 18.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EKG14066.1 - 0.005 15.9 0.1 0.013 14.6 0.0 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EKG14066.1 - 0.038 13.1 0.1 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Wax2_C PF12076.3 EKG14066.1 - 0.068 12.9 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 WAX2 C-terminal domain DUF4066 PF13278.1 EKG14067.1 - 6.2e-25 87.3 0.0 1e-21 76.9 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EKG14067.1 - 9.8e-10 38.0 0.0 1.8e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family SNO PF01174.14 EKG14067.1 - 0.08 12.5 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 SNO glutamine amidotransferase family ADH_zinc_N PF00107.21 EKG14068.1 - 7.9e-24 83.6 0.1 1.6e-23 82.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG14068.1 - 6e-21 74.2 0.4 1.6e-20 72.8 0.3 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Mito_carr PF00153.22 EKG14069.1 - 4.9e-50 167.2 0.6 1.1e-19 69.9 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.10 EKG14070.1 - 4.4e-24 84.9 12.4 5.2e-24 84.7 8.6 1.1 1 0 0 1 1 1 1 Chromate transporter Cupin_2 PF07883.6 EKG14071.1 - 2.9e-05 23.4 0.2 5.4e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EKG14071.1 - 7.9e-05 22.1 0.1 0.00019 20.9 0.1 1.5 1 0 0 1 1 1 1 Cupin Rho_N PF07498.7 EKG14071.1 - 0.013 15.2 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Cupin_6 PF12852.2 EKG14071.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Cupin PIH1 PF08190.7 EKG14071.1 - 0.038 13.4 0.1 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 GPI PF06560.6 EKG14071.1 - 0.044 12.8 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) ARD PF03079.9 EKG14071.1 - 0.066 13.1 0.2 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 ARD/ARD' family Gly-zipper_YMGG PF13441.1 EKG14071.1 - 0.37 10.3 3.8 0.66 9.5 2.7 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Cullin PF00888.17 EKG14072.1 - 1.9e-204 680.5 6.6 2.6e-204 680.0 4.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EKG14072.1 - 1e-27 95.7 4.3 4.1e-27 93.8 3.0 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain MRJP PF03022.11 EKG14074.1 - 3.1e-21 75.8 0.0 4.9e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein ResIII PF04851.10 EKG14076.1 - 1.2e-24 87.1 0.0 4.6e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKG14076.1 - 2.1e-14 53.1 0.0 4.7e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG14076.1 - 1.4e-12 47.4 0.3 2.9e-12 46.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EKG14076.1 - 0.00042 19.3 0.0 0.00083 18.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EKG14076.1 - 0.02 15.0 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Transglut_core PF01841.14 EKG14076.1 - 0.033 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily PGAP1 PF07819.8 EKG14077.1 - 3.7e-87 291.6 0.0 5.7e-87 291.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EKG14077.1 - 3.4e-06 26.8 0.1 7.6e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG14077.1 - 1.1e-05 25.4 0.3 1.1e-05 25.4 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG14077.1 - 0.0026 17.3 0.0 0.0053 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EKG14077.1 - 0.0054 16.0 0.1 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Esterase PF00756.15 EKG14077.1 - 0.065 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative esterase LCAT PF02450.10 EKG14077.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase COesterase PF00135.23 EKG14077.1 - 0.16 10.6 0.0 0.58 8.7 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family CTP_transf_1 PF01148.15 EKG14079.1 - 2.2e-80 270.0 31.4 2.7e-80 269.7 21.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 EKG14080.1 - 3.7e-27 94.7 0.0 7.9e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DivIC PF04977.10 EKG14080.1 - 0.0087 15.5 6.5 0.37 10.3 0.1 2.4 2 0 0 2 2 2 2 Septum formation initiator IncA PF04156.9 EKG14080.1 - 0.087 12.4 3.1 0.15 11.6 2.1 1.3 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 EKG14080.1 - 0.18 9.1 8.0 0.25 8.6 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.9 EKG14080.1 - 2.4 7.7 7.6 4.1 6.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Pro-kuma_activ PF09286.6 EKG14081.1 - 3.1e-40 137.5 0.3 1.2e-39 135.5 0.2 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EKG14081.1 - 8.1e-10 38.3 0.1 1.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Hydrolase PF00702.21 EKG14082.1 - 3.7e-24 86.3 0.0 2.2e-23 83.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EKG14082.1 - 8.6e-23 80.5 0.1 5.8e-22 77.8 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EKG14082.1 - 2e-20 73.7 0.0 3.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG14082.1 - 4.9e-05 23.1 0.0 0.00025 20.9 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKG14082.1 - 0.00076 19.1 0.0 0.0097 15.5 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_1c PF00749.16 EKG14083.1 - 4.1e-97 324.6 0.7 9.3e-95 316.8 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EKG14083.1 - 1.1e-32 113.0 0.0 3.2e-32 111.5 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Tricorn_C1 PF14684.1 EKG14084.1 - 0.44 10.4 3.5 0.45 10.4 0.7 2.2 3 0 0 3 3 3 0 Tricorn protease C1 domain Ank_2 PF12796.2 EKG14085.1 - 7.7e-16 58.2 0.1 2.1e-08 34.3 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKG14085.1 - 3.7e-13 48.5 1.7 6.9e-05 22.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EKG14085.1 - 7.7e-12 45.4 1.9 8.7e-06 26.1 0.2 4.4 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG14085.1 - 5.9e-11 42.2 0.8 0.00036 20.6 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG14085.1 - 5.8e-10 38.4 2.2 0.01 16.0 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EKG14085.1 - 0.0031 17.1 0.4 0.023 14.3 0.3 2.2 1 1 0 1 1 1 1 KilA-N domain ADIP PF11559.3 EKG14085.1 - 1 9.2 8.7 0.19 11.6 3.5 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Complex1_LYR_1 PF13232.1 EKG14086.1 - 6.3e-09 35.9 0.8 2e-08 34.2 0.6 1.9 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EKG14086.1 - 1.8e-06 27.6 0.9 4.8e-06 26.2 0.6 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Acetyltransf_1 PF00583.19 EKG14087.1 - 7.6e-15 54.7 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG14087.1 - 1.6e-07 31.3 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG14087.1 - 4.6e-07 29.9 0.0 8e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG14087.1 - 1.7e-06 27.7 0.0 3.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKG14087.1 - 1.4e-05 25.3 0.0 1.7e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG14087.1 - 0.034 13.9 0.0 0.15 11.9 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG14087.1 - 0.036 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 EKG14087.1 - 0.038 13.2 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family DUF3749 PF12568.3 EKG14087.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EIF_2_alpha PF07541.7 EKG14088.1 - 4.2e-38 129.5 0.0 8.3e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EKG14088.1 - 7.3e-13 48.4 0.9 1.3e-12 47.6 0.6 1.4 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.7 EKG14089.1 - 6e-06 24.9 22.7 0.00027 19.5 15.7 2.2 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EKG14089.1 - 0.00022 20.5 26.1 0.0018 17.5 18.1 2.1 1 1 0 1 1 1 1 Ion transport protein Glyco_hydro_28 PF00295.12 EKG14090.1 - 5.6e-51 173.4 7.8 6.9e-51 173.1 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Lipocalin_6 PF13944.1 EKG14090.1 - 0.023 14.7 1.6 3.7 7.6 0.0 3.5 3 1 1 4 4 4 0 Lipocalin-like domain EF-hand_1 PF00036.27 EKG14092.1 - 0.018 14.3 1.4 0.11 11.8 0.0 2.3 2 0 0 2 2 2 0 EF hand Excalibur PF05901.6 EKG14092.1 - 0.044 14.1 1.8 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Excalibur calcium-binding domain EF-hand_6 PF13405.1 EKG14092.1 - 0.13 12.1 1.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.1 EKG14092.1 - 0.75 9.2 3.3 5.4 6.5 0.1 2.5 2 0 0 2 2 2 0 EF hand VCBS PF13517.1 EKG14092.1 - 3.7 7.9 8.4 1 9.7 0.2 2.8 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Solute_trans_a PF03619.11 EKG14094.1 - 1.2e-102 342.9 6.9 1.5e-102 342.6 4.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pex16 PF08610.5 EKG14094.1 - 8.7 5.2 7.1 14 4.5 4.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF1501 PF07394.7 EKG14095.1 - 0.12 11.1 0.1 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Serinc PF03348.10 EKG14098.1 - 4.6e-172 572.5 7.7 5.4e-172 572.3 5.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.11 EKG14099.1 - 9.1e-19 67.3 12.1 2.4e-18 65.9 7.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EKG14099.1 - 2.1e-13 50.1 2.5 4.2e-13 49.1 1.8 1.5 1 0 0 1 1 1 1 Nodulin-like VMA21 PF09446.5 EKG14099.1 - 0.93 9.4 4.7 1.1 9.2 0.0 3.2 3 0 0 3 3 3 0 VMA21-like domain Peptidase_S24 PF00717.18 EKG14100.1 - 2.1e-08 33.6 0.0 8.9e-08 31.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EKG14100.1 - 0.00085 18.8 0.0 0.077 12.5 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Iso_dh PF00180.15 EKG14101.1 - 2.7e-91 306.1 0.0 3.2e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RPAP3_C PF13877.1 EKG14101.1 - 0.078 12.9 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 GLTP PF08718.6 EKG14102.1 - 1.2e-47 161.6 0.0 1.9e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Eaf7 PF07904.8 EKG14103.1 - 2.1e-20 72.5 0.5 1.7e-18 66.3 0.0 2.3 2 0 0 2 2 2 2 Chromatin modification-related protein EAF7 NARG2_C PF10505.4 EKG14103.1 - 0.023 13.8 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus NAD_binding_10 PF13460.1 EKG14105.1 - 1.8e-10 41.0 0.1 1.1e-09 38.5 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Vps52 PF04129.7 EKG14106.1 - 5.4e-127 424.4 0.1 6.7e-127 424.0 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EKG14106.1 - 1.4e-05 23.5 2.5 2e-05 22.9 1.7 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF1664 PF07889.7 EKG14106.1 - 0.079 12.7 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) eIF-5a PF01287.15 EKG14107.1 - 7.3e-26 89.9 0.4 1e-25 89.4 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EKG14107.1 - 0.00077 19.0 0.3 0.0018 17.9 0.2 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EKG14107.1 - 0.0025 17.6 0.1 0.006 16.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain Ribosomal_L40e PF01020.12 EKG14108.1 - 1.5e-29 101.3 11.0 1.5e-29 101.3 7.6 1.7 2 0 0 2 2 2 1 Ribosomal L40e family ubiquitin PF00240.18 EKG14108.1 - 6.6e-29 99.1 1.3 1.8e-28 97.6 0.9 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKG14108.1 - 2.1e-15 56.1 0.6 3.9e-15 55.2 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EKG14108.1 - 0.00065 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Ubiquitin_2 PF14560.1 EKG14108.1 - 0.0028 17.8 0.1 0.006 16.8 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EKG14108.1 - 0.015 15.2 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RrnaAD PF00398.15 EKG14108.1 - 0.059 12.3 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Transaldolase PF00923.14 EKG14109.1 - 1.3e-42 145.9 0.1 1.6e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 Transaldolase Ribosomal_L1 PF00687.16 EKG14111.1 - 6.4e-60 202.2 2.1 6.4e-60 202.2 1.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Sulfate_transp PF00916.15 EKG14112.1 - 1.7e-54 184.7 2.8 2.4e-54 184.2 1.3 1.6 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EKG14112.1 - 9.1e-28 95.7 1.5 3.2e-27 94.0 1.1 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EKG14112.1 - 5.9e-17 61.1 0.0 1.1e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EKG14112.1 - 4.7e-06 26.5 0.0 1.8e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 STAS domain Sugar_tr PF00083.19 EKG14114.1 - 2.9e-39 134.9 19.0 5.2e-39 134.0 13.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG14114.1 - 1.4e-34 119.4 34.5 4.3e-32 111.1 13.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EKG14114.1 - 0.0022 16.5 17.1 0.017 13.6 2.6 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like BTB PF00651.26 EKG14115.1 - 1.1e-08 35.0 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AAA PF00004.24 EKG14117.1 - 1.3e-10 41.5 0.0 2.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EKG14117.1 - 2.5e-05 23.9 0.1 0.00023 20.8 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EKG14117.1 - 2.6e-05 23.3 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKG14117.1 - 4.8e-05 23.5 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKG14117.1 - 0.00017 21.3 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EKG14117.1 - 0.00028 19.7 0.0 0.00047 18.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EKG14117.1 - 0.0019 19.0 0.0 0.014 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKG14117.1 - 0.003 17.4 0.0 0.0091 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKG14117.1 - 0.0058 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKG14117.1 - 0.0067 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG14117.1 - 0.011 15.6 0.0 0.061 13.3 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 EKG14117.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 EKG14117.1 - 0.033 13.2 0.0 0.084 11.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EKG14117.1 - 0.036 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EKG14117.1 - 0.043 14.1 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EKG14118.1 - 2.3e-10 39.7 9.8 1.6e-07 30.4 6.0 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Trypan_glycop PF00913.14 EKG14118.1 - 0.27 10.1 0.4 0.41 9.4 0.3 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) MFS_1 PF07690.11 EKG14119.1 - 4e-14 52.0 17.5 4.7e-14 51.8 11.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EKG14119.1 - 3.7e-07 29.7 2.9 8.9e-07 28.5 2.0 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DUF423 PF04241.10 EKG14119.1 - 0.051 13.5 0.6 0.051 13.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF423) Ldh_1_N PF00056.18 EKG14120.1 - 8.7e-43 145.5 0.0 1.4e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EKG14120.1 - 6.6e-42 143.1 0.0 1.6e-41 141.9 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EKG14120.1 - 0.0036 16.0 0.0 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EKG14120.1 - 0.082 13.2 0.4 0.36 11.1 0.0 2.3 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EKG14121.1 - 7.3e-06 25.4 0.0 7.8e-06 25.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG14121.1 - 0.028 14.4 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding cwf21 PF08312.7 EKG14121.1 - 0.035 13.9 0.2 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 cwf21 domain Carn_acyltransf PF00755.15 EKG14122.1 - 1.9e-179 597.5 0.0 2.2e-179 597.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DASH_Ask1 PF08655.5 EKG14123.1 - 1.6e-32 111.1 0.0 2.9e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 adh_short PF00106.20 EKG14124.1 - 1.7e-32 112.6 0.4 2.4e-32 112.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG14124.1 - 2.4e-23 83.1 0.4 2.9e-23 82.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG14124.1 - 5.2e-12 45.7 0.3 9.1e-12 45.0 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG14124.1 - 0.00013 21.4 0.4 0.00031 20.2 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 EKG14124.1 - 0.0052 16.9 0.3 0.047 13.8 0.0 2.6 3 0 0 3 3 3 1 Helix-hairpin-helix domain HAD PF12710.2 EKG14124.1 - 0.021 15.0 0.0 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mo-co_dimer PF03404.11 EKG14125.1 - 1e-54 183.6 0.1 2e-54 182.7 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EKG14125.1 - 1e-50 171.4 0.1 2e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EKG14125.1 - 1.3e-32 111.8 0.0 2.3e-32 111.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EKG14125.1 - 1.9e-24 85.2 0.0 3.9e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EKG14125.1 - 3.3e-24 85.5 0.0 7.8e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EKG14125.1 - 0.0023 17.8 0.0 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 EKG14127.1 - 5.2e-32 110.3 0.0 1.1e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.1 EKG14127.1 - 2.7e-16 59.1 0.0 7.1e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 EKG14127.1 - 7.5e-14 51.5 4.6 2.7e-11 43.3 2.1 2.5 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 EKG14127.1 - 1.5e-13 50.1 0.3 4.4e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EKG14127.1 - 7.7e-10 38.2 0.0 1.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_2 PF07992.9 EKG14127.1 - 3.5e-08 33.5 0.0 6.5e-06 26.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M28 PF04389.12 EKG14128.1 - 0.00023 20.9 0.8 0.00039 20.1 0.6 1.4 1 0 0 1 1 1 1 Peptidase family M28 V-SNARE_C PF12352.3 EKG14129.1 - 3.1e-13 49.5 0.2 3.1e-13 49.5 0.2 1.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EKG14129.1 - 2.3e-05 24.0 0.5 0.00013 21.5 0.0 1.9 2 0 0 2 2 2 1 Sec20 Sec2p PF06428.6 EKG14129.1 - 0.12 12.2 1.4 2.2 8.1 0.6 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Cast PF10174.4 EKG14129.1 - 0.78 7.7 5.5 2.9 5.8 0.0 2.0 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Myb_DNA-bind_3 PF12776.2 EKG14130.1 - 0.0059 17.2 0.4 1.8 9.2 0.2 2.1 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain SBDS_C PF09377.5 EKG14130.1 - 0.041 13.5 0.2 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 SBDS protein C-terminal domain Myb_DNA-bind_5 PF13873.1 EKG14130.1 - 0.27 11.1 2.1 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Transgly_assoc PF04226.8 EKG14131.1 - 1.8 8.7 8.8 3.1 7.9 6.1 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein TPR_11 PF13414.1 EKG14132.1 - 8.4e-18 63.7 0.9 1.7e-10 40.3 0.1 5.4 4 2 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EKG14132.1 - 4.4e-09 35.5 2.8 0.00023 20.6 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG14132.1 - 5e-08 32.2 13.7 0.00013 21.5 0.0 6.3 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG14132.1 - 4.9e-07 29.4 0.3 0.17 12.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG14132.1 - 4.6e-06 27.1 0.6 4.6e-06 27.1 0.4 5.4 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKG14132.1 - 0.00025 20.8 7.7 0.41 10.6 0.1 5.3 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG14132.1 - 0.00038 20.0 0.1 0.074 12.8 0.0 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKG14132.1 - 0.00047 19.7 10.6 0.0082 15.8 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKG14132.1 - 0.00097 19.5 0.7 0.00097 19.5 0.5 6.3 4 3 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG14132.1 - 0.0089 16.3 7.6 0.038 14.3 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EKG14132.1 - 0.089 12.9 1.4 0.95 9.6 0.1 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKG14132.1 - 0.16 12.4 3.3 4.5 7.9 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat LDB19 PF13002.2 EKG14133.1 - 1.1e-14 54.3 0.1 2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like TRAP-gamma PF07074.7 EKG14135.1 - 0.44 10.0 5.7 0.24 10.9 0.7 2.0 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) T2SM PF04612.7 EKG14138.1 - 0.053 13.3 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M zf-C2H2_4 PF13894.1 EKG14138.1 - 2.7 8.5 11.4 2.4 8.7 2.6 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger AMP-binding PF00501.23 EKG14140.1 - 9.7e-35 119.7 0.0 1.3e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EKG14140.1 - 1.2e-23 84.5 0.0 4.8e-23 82.5 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EKG14140.1 - 9.7e-07 28.9 0.1 2.6e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EKG14140.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG14140.1 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EKG14140.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Aurora-A_bind PF09041.5 EKG14141.1 - 0.039 13.7 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Aurora-A binding Pox_LP_H2 PF03356.10 EKG14141.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral late protein H2 Atg14 PF10186.4 EKG14144.1 - 0.00062 18.8 4.4 0.00074 18.5 3.1 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 EKG14144.1 - 0.002 16.6 6.3 0.0023 16.4 4.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Nsp1_C PF05064.8 EKG14144.1 - 0.0031 17.1 5.0 0.0048 16.5 3.5 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF334 PF03904.8 EKG14144.1 - 0.0085 15.4 4.1 0.012 14.9 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF334) Mitofilin PF09731.4 EKG14144.1 - 0.0085 14.7 11.2 0.011 14.3 7.8 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein IncA PF04156.9 EKG14144.1 - 0.0087 15.6 13.4 0.013 15.1 9.3 1.2 1 0 0 1 1 1 1 IncA protein Spc7 PF08317.6 EKG14144.1 - 0.016 13.8 12.1 0.023 13.3 8.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EKG14144.1 - 0.019 15.3 6.5 0.044 14.1 4.5 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Tweety PF04906.8 EKG14144.1 - 0.028 12.8 0.7 0.037 12.4 0.5 1.1 1 0 0 1 1 1 0 Tweety Macoilin PF09726.4 EKG14144.1 - 0.032 12.5 8.4 0.041 12.1 5.8 1.2 1 0 0 1 1 1 0 Transmembrane protein ATG16 PF08614.6 EKG14144.1 - 0.05 13.4 17.4 0.22 11.3 12.1 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF964 PF06133.6 EKG14144.1 - 0.086 12.8 8.7 0.13 12.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF4200 PF13863.1 EKG14144.1 - 0.12 12.3 18.3 0.22 11.4 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DSBA PF01323.15 EKG14144.1 - 0.12 11.8 0.5 0.21 11.1 0.3 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain ApoO PF09769.4 EKG14144.1 - 0.13 11.9 0.4 0.23 11.1 0.3 1.5 1 0 0 1 1 1 0 Apolipoprotein O Fib_alpha PF08702.5 EKG14144.1 - 0.13 12.3 8.1 0.21 11.6 5.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LMP PF04778.7 EKG14144.1 - 0.14 11.8 7.7 0.27 10.9 5.3 1.5 1 1 0 1 1 1 0 LMP repeated region DUF3552 PF12072.3 EKG14144.1 - 0.18 11.0 16.6 0.28 10.3 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HSP70 PF00012.15 EKG14144.1 - 0.18 9.6 5.2 0.23 9.3 3.6 1.1 1 0 0 1 1 1 0 Hsp70 protein Laminin_II PF06009.7 EKG14144.1 - 0.22 11.2 8.3 0.34 10.6 5.7 1.2 1 0 0 1 1 1 0 Laminin Domain II MMPL PF03176.10 EKG14144.1 - 0.27 9.8 0.6 0.38 9.4 0.4 1.2 1 0 0 1 1 1 0 MMPL family DUF2935 PF11155.3 EKG14144.1 - 0.29 11.2 3.3 0.46 10.5 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) IFT57 PF10498.4 EKG14144.1 - 0.32 9.7 10.2 0.48 9.1 7.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Reo_sigmaC PF04582.7 EKG14144.1 - 0.32 10.1 1.5 0.41 9.7 1.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cluap1 PF10234.4 EKG14144.1 - 0.35 10.0 11.4 0.53 9.4 7.9 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 COG5 PF10392.4 EKG14144.1 - 0.42 10.5 7.4 0.69 9.8 5.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 AAA_13 PF13166.1 EKG14144.1 - 0.43 8.9 8.9 0.58 8.5 6.2 1.1 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EKG14144.1 - 0.51 9.9 13.3 0.79 9.3 9.2 1.2 1 0 0 1 1 1 0 Mnd1 family Sec20 PF03908.8 EKG14144.1 - 0.56 9.9 3.0 0.9 9.2 2.1 1.3 1 0 0 1 1 1 0 Sec20 TMPIT PF07851.8 EKG14144.1 - 0.82 8.6 8.4 1 8.3 5.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF972 PF06156.8 EKG14144.1 - 0.92 9.8 15.1 0.42 10.9 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IFT46_B_C PF12317.3 EKG14144.1 - 1.1 8.5 3.8 1.6 8.0 2.6 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Exonuc_VII_L PF02601.10 EKG14144.1 - 1.1 8.3 7.0 1.5 7.8 4.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.3 EKG14144.1 - 1.2 9.0 21.6 2.7 7.8 8.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.9 EKG14144.1 - 1.5 8.7 16.7 0.064 13.1 7.4 1.8 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.4 EKG14144.1 - 3.1 8.0 5.9 6.3 7.0 4.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Tho2 PF11262.3 EKG14144.1 - 3.1 6.7 6.4 4.8 6.1 4.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF904 PF06005.7 EKG14144.1 - 3.2 8.1 22.4 4.9 7.5 9.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) DUF1664 PF07889.7 EKG14144.1 - 3.4 7.4 8.2 11 5.8 0.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 EKG14144.1 - 4.1 7.7 12.1 6.4 7.1 8.4 1.2 1 0 0 1 1 1 0 Snapin/Pallidin V_ATPase_I PF01496.14 EKG14144.1 - 4.1 5.1 10.2 5.2 4.7 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EKG14144.1 - 6.3 5.7 15.2 9.3 5.1 10.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 EKG14144.1 - 6.6 6.7 12.7 2.7 7.9 1.1 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Prominin PF05478.6 EKG14144.1 - 6.9 4.0 6.8 9.1 3.6 4.7 1.1 1 0 0 1 1 1 0 Prominin Nup88 PF10168.4 EKG14144.1 - 9 3.9 12.6 12 3.5 8.8 1.1 1 0 0 1 1 1 0 Nuclear pore component DSPc PF00782.15 EKG14145.1 - 5.7e-12 45.3 0.1 1.2e-11 44.3 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EKG14145.1 - 0.025 13.4 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase p450 PF00067.17 EKG14148.1 - 2.5e-54 184.5 0.0 3.5e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.19 EKG14149.1 - 8.4e-33 113.7 1.1 1.5e-32 112.9 0.5 1.6 2 0 0 2 2 2 1 Beta-lactamase F-box-like PF12937.2 EKG14149.1 - 3.2e-07 29.9 0.9 1.1e-06 28.2 0.6 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EKG14149.1 - 3.4e-05 23.4 2.1 0.46 10.7 0.1 4.5 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 EKG14149.1 - 0.00021 20.8 1.4 0.68 9.6 0.1 3.9 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG14149.1 - 0.0024 17.5 3.8 5.2 6.9 0.1 4.6 3 1 2 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 EKG14149.1 - 0.006 16.4 3.4 12 6.3 0.0 5.1 4 0 0 4 4 4 1 Leucine Rich Repeat F-box PF00646.28 EKG14149.1 - 0.022 14.4 1.9 0.035 13.7 0.2 2.2 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 EKG14149.1 - 0.11 12.7 2.2 8.9 7.0 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat zf-RING_2 PF13639.1 EKG14150.1 - 1.2e-15 57.0 7.1 1.2e-15 57.0 4.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKG14150.1 - 1e-10 41.1 9.5 1.3e-08 34.3 1.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG14150.1 - 3.2e-08 33.4 6.1 3.2e-08 33.4 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG14150.1 - 9.2e-08 31.6 13.8 3.4e-06 26.6 3.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG14150.1 - 3.6e-07 30.1 3.2 3.6e-07 30.1 2.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_3 PF14369.1 EKG14150.1 - 1.3e-05 25.0 12.0 0.00022 21.1 4.2 2.5 2 0 0 2 2 2 2 zinc-finger zf-RING_5 PF14634.1 EKG14150.1 - 4.4e-05 23.1 12.4 5.8e-05 22.7 2.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain HypA PF01155.14 EKG14150.1 - 0.0061 16.2 0.9 0.0061 16.2 0.6 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-C3HC4_4 PF15227.1 EKG14150.1 - 0.0093 15.8 13.8 0.44 10.4 0.9 2.5 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING Baculo_RING PF05883.6 EKG14150.1 - 0.018 14.8 7.2 1.4 8.7 0.9 3.2 3 0 0 3 3 3 0 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 EKG14150.1 - 0.022 14.6 2.9 0.022 14.6 2.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EKG14150.1 - 0.17 11.4 14.0 0.43 10.2 3.0 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Serglycin PF04360.7 EKG14150.1 - 1.2 8.9 9.6 0.086 12.5 2.8 1.9 2 0 0 2 2 2 0 Serglycin zinc-ribbons_6 PF07191.7 EKG14150.1 - 1.2 9.0 9.1 0.53 10.1 0.7 2.5 3 0 0 3 3 2 0 zinc-ribbons PHD PF00628.24 EKG14150.1 - 1.2 8.8 17.3 0.6 9.8 4.2 2.8 2 1 0 2 2 2 0 PHD-finger DZR PF12773.2 EKG14150.1 - 2.6 7.9 10.3 0.71 9.7 0.5 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.1 EKG14150.1 - 2.6 7.8 6.1 1.7 8.4 2.4 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EKG14150.1 - 4 7.2 12.0 2.5 7.8 0.3 3.0 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Fis1_TPR_C PF14853.1 EKG14151.1 - 6.4e-25 86.7 1.7 1.1e-24 86.0 1.2 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EKG14151.1 - 6.4e-17 60.5 0.0 1.2e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_16 PF13432.1 EKG14151.1 - 0.00048 20.7 0.6 0.00083 19.9 0.4 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG14151.1 - 0.0011 18.7 3.8 0.0022 17.7 2.7 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKG14151.1 - 0.0096 15.5 0.2 0.015 14.9 0.2 1.3 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EKG14151.1 - 0.067 13.1 0.3 0.096 12.6 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG14151.1 - 0.087 13.3 0.4 0.27 11.7 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKG14151.1 - 0.64 9.7 4.2 1.3 8.7 2.9 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 EKG14152.1 - 3e-30 104.3 1.9 4.3e-30 103.8 0.1 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APG6 PF04111.7 EKG14152.1 - 0.026 13.5 4.8 0.034 13.2 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 EKG14152.1 - 0.029 14.0 6.7 0.02 14.6 2.8 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Phage_HK97_TLTM PF06120.6 EKG14152.1 - 0.052 12.8 0.4 0.066 12.5 0.3 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF4623 PF15416.1 EKG14152.1 - 0.07 11.4 0.0 0.091 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) Troponin PF00992.15 EKG14152.1 - 0.19 11.7 4.4 0.25 11.4 3.0 1.2 1 0 0 1 1 1 0 Troponin V_ATPase_I PF01496.14 EKG14152.1 - 0.2 9.5 1.0 0.22 9.3 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family End3 PF12761.2 EKG14152.1 - 0.28 10.7 5.0 0.49 10.0 0.9 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF4164 PF13747.1 EKG14152.1 - 0.34 11.0 5.0 1.1 9.4 3.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) TMF_DNA_bd PF12329.3 EKG14152.1 - 0.46 10.3 7.3 8.9 6.1 5.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.1 EKG14152.1 - 0.6 10.4 3.6 0.95 9.8 1.0 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Wbp11 PF09429.5 EKG14152.1 - 0.65 10.0 3.2 3.6 7.6 1.4 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 IncA PF04156.9 EKG14152.1 - 0.76 9.3 7.1 1 8.8 4.9 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EKG14152.1 - 0.83 10.0 4.3 0.77 10.1 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nup54 PF13874.1 EKG14152.1 - 1.5 8.4 5.7 3 7.5 3.9 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TBPIP PF07106.8 EKG14152.1 - 1.6 8.2 6.0 4.1 6.9 1.2 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pox_A_type_inc PF04508.7 EKG14152.1 - 3 7.8 8.5 4.9 7.2 0.1 3.1 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat F-box PF00646.28 EKG14153.1 - 0.021 14.4 0.0 0.15 11.7 0.0 2.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EKG14153.1 - 0.026 14.2 0.2 0.074 12.7 0.1 1.9 2 0 0 2 2 2 0 F-box-like GYF PF02213.11 EKG14154.1 - 5e-16 58.0 0.0 1.2e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 GYF domain Bestrophin PF01062.16 EKG14156.1 - 3.6e-47 160.7 0.1 1.6e-45 155.3 0.1 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ABC2_membrane PF01061.19 EKG14158.1 - 5.2e-14 51.9 0.1 6.6e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ECF-ribofla_trS PF07155.7 EKG14158.1 - 0.08 12.6 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component PDR_CDR PF06422.7 EKG14159.1 - 1.6e-30 104.8 0.0 3.2e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.22 EKG14159.1 - 4.5e-18 65.8 0.0 6.6e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EKG14159.1 - 8.4e-15 54.4 10.6 4.2e-13 48.9 3.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter AAA_25 PF13481.1 EKG14159.1 - 1.8e-06 27.5 0.4 4.5e-06 26.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG14159.1 - 4.4e-06 26.6 0.0 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKG14159.1 - 0.00033 19.8 0.0 0.00058 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG14159.1 - 0.0008 19.4 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 EKG14159.1 - 0.0031 16.9 0.9 0.0052 16.2 0.6 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EKG14159.1 - 0.0033 16.9 0.1 0.0078 15.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EKG14159.1 - 0.0047 16.1 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EKG14159.1 - 0.0054 17.5 0.0 0.027 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG14159.1 - 0.0072 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EKG14159.1 - 0.0077 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG14159.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EKG14159.1 - 0.057 13.0 0.2 0.6 9.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 EKG14159.1 - 0.12 12.2 0.1 10 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EKG14159.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.2 EKG14159.1 - 0.28 10.1 4.7 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein HNOB PF07700.10 EKG14160.1 - 0.057 12.9 0.5 0.083 12.4 0.4 1.2 1 0 0 1 1 1 0 Heme NO binding DUF1977 PF09320.6 EKG14160.1 - 1.4 9.2 6.5 3.4 7.9 4.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) AA_permease_2 PF13520.1 EKG14161.1 - 1.9e-17 62.9 7.9 3.2e-17 62.1 5.5 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG14161.1 - 8.2e-05 21.1 0.1 8.2e-05 21.1 0.1 2.1 2 0 0 2 2 2 2 Amino acid permease Ifi-6-16 PF06140.8 EKG14162.1 - 0.00019 21.1 8.9 0.00031 20.4 6.2 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Fungal_trans PF04082.13 EKG14163.1 - 2.6e-09 36.3 2.2 2.7e-09 36.3 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain Ribosomal_S7 PF00177.16 EKG14165.1 - 0.019 14.5 0.1 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e Matrilin_ccoil PF10393.4 EKG14165.1 - 0.12 11.8 0.3 4.9 6.6 0.0 2.7 2 1 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin SWIRM PF04433.12 EKG14166.1 - 9.1e-35 118.6 0.1 2e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EKG14166.1 - 2.9e-08 33.6 0.1 5.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG14166.1 - 1.9e-06 27.9 0.6 5e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EKG14166.1 - 0.017 14.6 2.9 0.085 12.4 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type ETF PF01012.16 EKG14167.1 - 4.2e-44 150.1 0.7 1.7e-43 148.2 0.1 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EKG14167.1 - 2.3e-34 116.8 0.0 4.8e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Ion_trans_2 PF07885.11 EKG14168.1 - 2.3e-31 107.3 16.8 2.1e-16 59.3 3.7 2.8 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.26 EKG14168.1 - 0.034 13.3 0.4 0.034 13.3 0.3 3.5 3 1 0 3 3 3 0 Ion transport protein Lig_chan PF00060.21 EKG14168.1 - 0.14 11.8 8.7 0.12 12.0 1.8 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel Shisa PF13908.1 EKG14168.1 - 0.17 12.0 0.6 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Cu_amine_oxid PF01179.15 EKG14169.1 - 1.5e-165 550.9 0.0 2.1e-165 550.4 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EKG14169.1 - 1.3e-07 31.5 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EKG14169.1 - 3.3e-05 23.8 0.1 8.8e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain p450 PF00067.17 EKG14170.1 - 2.4e-15 56.0 0.0 3e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EKG14171.1 - 5.2e-16 58.6 1.4 8.2e-15 54.7 1.0 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG14171.1 - 2.5e-09 36.4 0.4 9.9e-06 24.6 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG14171.1 - 5.4e-07 29.5 0.3 1.3e-06 28.3 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG14171.1 - 1e-05 24.6 0.8 1.5e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EKG14171.1 - 3.5e-05 22.8 0.4 6.1e-05 22.0 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EKG14171.1 - 9.4e-05 22.3 0.1 0.0002 21.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG14171.1 - 0.00018 20.6 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EKG14171.1 - 0.00035 19.7 0.7 0.00047 19.3 0.5 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG14171.1 - 0.0012 19.2 0.0 0.008 16.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG14171.1 - 0.0013 17.2 0.2 0.0023 16.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EKG14171.1 - 0.0016 17.1 0.0 0.018 13.7 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EKG14171.1 - 0.0025 16.8 0.4 0.0093 14.9 0.2 2.0 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EKG14171.1 - 0.0036 17.3 0.2 0.0088 16.1 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EKG14171.1 - 0.016 14.8 0.2 0.029 14.0 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EKG14171.1 - 0.018 14.6 2.4 0.048 13.2 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EKG14171.1 - 0.041 13.6 0.8 0.21 11.3 0.1 2.3 3 0 0 3 3 2 0 FAD-NAD(P)-binding SE PF08491.5 EKG14171.1 - 0.09 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DUF1344 PF07076.6 EKG14171.1 - 0.15 11.6 0.2 0.49 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) CAP_N PF01213.14 EKG14172.1 - 5.7e-75 252.5 6.8 5.7e-75 252.5 4.7 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EKG14172.1 - 2.1e-59 199.4 0.0 2.8e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EKG14172.1 - 0.004 16.5 1.2 0.017 14.5 0.8 1.9 1 1 1 2 2 2 2 Tubulin binding cofactor C DUF3597 PF12200.3 EKG14172.1 - 6.2 7.2 7.2 4.3 7.7 1.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3597) PfkB PF00294.19 EKG14173.1 - 7.2e-14 51.6 0.1 1.2e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MraY_sig1 PF10555.4 EKG14174.1 - 0.49 9.8 0.1 0.49 9.8 0.1 2.1 2 0 0 2 2 2 0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 Ribonuclease_3 PF00636.21 EKG14175.1 - 1.7e-06 28.4 0.0 4.3e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EKG14175.1 - 3.7e-06 26.9 0.0 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EKG14175.1 - 8.8e-05 23.0 0.0 0.00021 21.8 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif GTP_EFTU PF00009.22 EKG14176.1 - 2.7e-31 108.4 0.0 2e-30 105.6 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EKG14176.1 - 5.3e-17 61.6 0.0 1.4e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EKG14176.1 - 2.6e-11 43.4 1.9 5.3e-09 36.0 0.1 3.2 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKG14176.1 - 1.7e-06 28.0 0.1 1.1e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EKG14176.1 - 0.00058 19.4 0.0 0.0022 17.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EKG14176.1 - 0.00092 18.8 0.0 0.0026 17.3 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EKG14176.1 - 0.051 13.7 0.0 0.25 11.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG14176.1 - 0.071 13.0 0.0 0.071 13.0 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Chitin_synth_2 PF03142.10 EKG14177.1 - 1.5e-252 838.6 2.1 2e-252 838.2 1.5 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EKG14177.1 - 2.7e-172 574.3 0.0 3.9e-172 573.8 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EKG14177.1 - 5.8e-21 74.0 0.0 3.3e-14 52.4 0.0 3.1 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EKG14177.1 - 2e-16 59.4 0.5 7.6e-16 57.6 0.3 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EKG14177.1 - 3.7e-15 56.1 5.3 3.7e-15 56.1 3.6 3.2 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG14177.1 - 2.9e-13 50.1 0.5 1.1e-10 41.6 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EKG14177.1 - 2.2e-05 24.1 0.0 0.0022 17.7 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EKG14177.1 - 0.0014 17.9 0.2 0.0068 15.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.1 EKG14177.1 - 0.0046 17.0 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKG14177.1 - 0.0058 15.8 0.0 0.035 13.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG14177.1 - 0.049 13.6 0.1 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EKG14177.1 - 0.074 12.4 0.1 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG14177.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Chitin_synth_2 PF03142.10 EKG14178.1 - 2.5e-236 785.1 0.1 3.4e-236 784.7 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EKG14178.1 - 6.4e-52 176.5 0.0 3.4e-51 174.1 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EKG14178.1 - 7.9e-18 64.8 2.8 7.9e-18 64.8 2.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG14178.1 - 2.5e-14 53.6 0.0 4e-12 46.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EKG14178.1 - 1e-13 50.8 0.0 1.4e-07 31.1 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EKG14178.1 - 1.1e-13 50.6 0.5 2.5e-12 46.3 0.7 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EKG14178.1 - 2.1e-06 27.1 0.0 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EKG14178.1 - 0.0024 17.5 0.0 0.029 14.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Lipase_GDSL PF00657.17 EKG14179.1 - 4.5e-13 49.5 0.0 8e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKG14179.1 - 0.00031 20.9 0.1 0.00089 19.4 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family YrhC PF14143.1 EKG14179.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 YrhC-like protein BCDHK_Adom3 PF10436.4 EKG14180.1 - 1.6e-42 144.7 0.0 2.2e-42 144.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EKG14180.1 - 3.7e-15 55.6 0.2 6.9e-13 48.2 0.1 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EKG14180.1 - 0.046 13.3 0.0 0.5 10.0 0.0 2.1 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2046 PF09755.4 EKG14182.1 - 0.0032 16.4 2.8 0.0087 14.9 0.5 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) Leu_zip PF15294.1 EKG14182.1 - 0.044 12.8 0.9 0.45 9.5 0.0 2.1 2 0 0 2 2 2 0 Leucine zipper SPX PF03105.14 EKG14182.1 - 0.046 13.4 7.3 0.2 11.4 5.1 1.9 1 1 0 1 1 1 0 SPX domain Chibby PF14645.1 EKG14182.1 - 0.076 12.9 1.8 0.31 10.9 0.0 2.6 2 1 0 2 2 2 0 Chibby family DUF2968 PF11180.3 EKG14182.1 - 0.079 12.3 5.3 0.21 10.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Med15_fungi PF05397.7 EKG14182.1 - 0.26 11.2 1.6 0.38 10.7 0.2 1.8 2 0 0 2 2 2 0 Mediator complex subunit 15 DivIC PF04977.10 EKG14182.1 - 0.36 10.3 5.3 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator MerR-DNA-bind PF09278.6 EKG14182.1 - 3 8.2 8.6 7.8 6.9 0.2 2.5 2 0 0 2 2 2 0 MerR, DNA binding Sec62 PF03839.11 EKG14183.1 - 3.7e-56 190.0 0.4 3.7e-56 190.0 0.3 1.5 2 0 0 2 2 2 1 Translocation protein Sec62 Enkurin PF13864.1 EKG14183.1 - 0.063 13.4 2.6 0.16 12.2 1.8 1.6 1 0 0 1 1 1 0 Calmodulin-binding DSBA PF01323.15 EKG14183.1 - 0.31 10.5 2.9 0.39 10.2 0.4 2.2 3 0 0 3 3 3 0 DSBA-like thioredoxin domain Ribosomal_L11_N PF03946.9 EKG14184.1 - 7.4e-18 63.7 0.0 1.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EKG14184.1 - 6.5e-11 42.2 0.3 1.1e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.1 EKG14185.1 - 1.6e-102 342.8 0.0 3.8e-54 183.3 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.23 EKG14185.1 - 2e-24 84.1 13.0 0.00011 21.6 0.0 6.1 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 EKG14185.1 - 8.7e-24 82.9 13.5 2.5e-10 39.8 0.1 5.2 5 0 0 5 5 5 4 TPR repeat TPR_2 PF07719.12 EKG14185.1 - 1.2e-17 62.3 14.1 0.00033 20.3 0.1 6.2 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EKG14185.1 - 5.8e-16 57.0 3.3 0.0013 18.3 0.0 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EKG14185.1 - 2.9e-14 52.7 7.5 1.4e-05 24.9 0.4 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EKG14185.1 - 1.9e-13 49.4 6.6 0.0011 19.0 0.0 5.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EKG14185.1 - 2e-13 49.6 4.6 0.035 14.7 0.0 6.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EKG14185.1 - 2.5e-12 47.0 13.3 7.7e-06 26.4 0.2 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EKG14185.1 - 6.4e-08 32.2 9.2 0.33 10.9 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG14185.1 - 1.6e-07 30.5 3.1 0.14 12.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKG14185.1 - 9.8e-06 25.8 17.3 0.00012 22.3 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG14185.1 - 2.2e-05 24.2 3.8 0.085 12.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKG14185.1 - 0.0036 17.6 3.8 23 5.7 0.0 4.8 4 1 1 5 5 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EKG14185.1 - 0.0082 16.2 1.3 0.15 12.2 0.0 3.0 2 1 2 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.3 EKG14185.1 - 0.39 9.4 0.1 1.3 7.6 0.0 1.9 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Myb_DNA-binding PF00249.26 EKG14186.1 - 5.5e-24 83.9 1.0 7.9e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG14186.1 - 1.5e-20 73.0 1.9 5.9e-14 51.9 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EKG14186.1 - 0.016 15.1 0.0 0.04 13.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Sigma70_r4_2 PF08281.7 EKG14186.1 - 0.032 13.7 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 EKG14186.1 - 0.04 13.5 0.2 0.093 12.4 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Myb_DNA-bind_4 PF13837.1 EKG14186.1 - 4.3 7.5 7.7 1.4 9.0 0.3 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Lectin_C PF00059.16 EKG14187.1 - 0.0014 19.2 3.9 0.0022 18.5 1.5 2.2 2 1 0 2 2 2 1 Lectin C-type domain bZIP_1 PF00170.16 EKG14187.1 - 0.052 13.5 0.2 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor DAO PF01266.19 EKG14188.1 - 3.8e-32 111.5 0.0 4.2e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase MIF4G PF02854.14 EKG14189.1 - 4.3e-66 222.3 0.0 5.1e-35 120.7 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EKG14189.1 - 1.7e-52 177.6 20.9 1.7e-52 177.6 14.5 3.5 4 0 0 4 4 4 1 Up-frameshift suppressor 2 RabGAP-TBC PF00566.13 EKG14192.1 - 1.2e-26 93.5 0.0 1.6e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF998 PF06197.8 EKG14192.1 - 0.021 14.1 2.0 0.05 12.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF998) MMS1_N PF10433.4 EKG14193.1 - 6.6e-94 314.8 0.0 1.1e-93 314.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EKG14193.1 - 3e-11 42.9 0.0 9e-09 34.8 0.0 2.7 3 0 0 3 3 3 2 CPSF A subunit region HPS3_N PF14761.1 EKG14193.1 - 0.37 10.1 0.0 28 3.9 0.0 2.4 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Yip1 PF04893.12 EKG14194.1 - 9.1e-12 44.8 14.0 1.3e-11 44.2 9.7 1.3 1 1 0 1 1 1 1 Yip1 domain CopD PF05425.8 EKG14194.1 - 0.21 11.8 5.2 0.83 9.8 0.6 2.3 2 0 0 2 2 2 0 Copper resistance protein D Transp_cyt_pur PF02133.10 EKG14195.1 - 2.1e-69 234.2 21.8 2.5e-69 233.9 15.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.7 EKG14196.1 - 1.1e-68 231.3 0.3 2.8e-49 167.5 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF917) HET-s_218-289 PF11558.3 EKG14196.1 - 0.041 13.8 0.0 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 Het-s 218-289 Glyco_transf_90 PF05686.7 EKG14198.1 - 7.1e-33 113.8 4.4 9e-33 113.5 3.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EKG14198.1 - 0.021 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Aminotran_5 PF00266.14 EKG14199.1 - 3.1e-16 59.1 0.0 6.5e-16 58.0 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EKG14199.1 - 0.013 14.4 0.1 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II PROL5-SMR PF15621.1 EKG14199.1 - 0.074 13.4 0.5 2.1 8.8 0.9 2.2 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family GRAS PF03514.9 EKG14200.1 - 0.064 11.9 0.3 0.093 11.4 0.2 1.2 1 0 0 1 1 1 0 GRAS domain family Pkinase PF00069.20 EKG14201.1 - 1.8e-16 60.0 0.0 3.5e-16 59.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG14201.1 - 1.4e-13 50.4 0.0 4e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase CENP-L PF13092.1 EKG14202.1 - 0.053 13.2 0.2 0.095 12.4 0.2 1.4 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Anticodon_1 PF08264.8 EKG14203.1 - 0.046 13.4 0.1 0.082 12.6 0.1 1.5 1 1 0 1 1 1 0 Anticodon-binding domain of tRNA Amidohydro_2 PF04909.9 EKG14204.1 - 2.4e-07 30.5 0.0 3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase STT3 PF02516.9 EKG14205.1 - 0.031 13.2 0.0 0.035 13.0 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit PIG-U PF06728.8 EKG14205.1 - 0.12 11.2 0.6 0.15 10.9 0.4 1.0 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U YrhK PF14145.1 EKG14206.1 - 0.012 15.2 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 YrhK-like protein zf-C4 PF00105.13 EKG14206.1 - 0.18 12.0 6.8 0.32 11.2 4.7 1.3 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) HET PF06985.6 EKG14207.1 - 3.7e-24 85.4 0.0 7.9e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pyr_redox_3 PF13738.1 EKG14209.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_5 PF12695.2 EKG14210.1 - 1.2e-10 41.3 1.6 2.5e-10 40.2 1.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG14210.1 - 2.3e-09 37.4 6.3 3.4e-09 36.9 4.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EKG14210.1 - 8.3e-07 28.4 0.6 1.6e-05 24.2 0.4 2.4 1 1 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 EKG14210.1 - 3.5e-06 26.3 0.0 0.00081 18.6 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EKG14210.1 - 0.0001 21.8 0.0 0.0004 19.8 0.0 2.0 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF3445 PF11927.3 EKG14212.1 - 6.1e-63 212.5 0.0 4.9e-46 157.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) DUF1320 PF07030.7 EKG14212.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1320) Lipase_GDSL_2 PF13472.1 EKG14213.1 - 1.2e-16 61.3 2.1 1.6e-16 60.9 1.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EKG14213.1 - 2e-08 34.3 1.1 2.9e-08 33.8 0.7 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Prenyltrans PF00432.16 EKG14213.1 - 2.5 7.7 4.6 3.4 7.3 1.2 2.3 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Glyco_hydro_43 PF04616.9 EKG14214.1 - 2.7e-26 92.2 0.1 4e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 KGG PF10685.4 EKG14215.1 - 3.6e-27 93.7 19.1 1.2e-12 47.3 2.3 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif VanY PF02557.12 EKG14215.1 - 0.079 12.7 0.3 0.075 12.8 0.2 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase BCS1_N PF08740.6 EKG14218.1 - 1.4e-25 89.9 0.1 8.1e-25 87.5 0.0 2.2 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EKG14218.1 - 1.1e-20 74.1 0.0 1.9e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG14218.1 - 9.4e-05 22.1 0.0 0.00035 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EKG14218.1 - 0.0029 18.4 0.0 0.0074 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG14218.1 - 0.0054 16.7 0.2 0.057 13.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG14218.1 - 0.0061 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EKG14218.1 - 0.025 13.7 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EKG14218.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ANF_receptor PF01094.23 EKG14218.1 - 0.053 12.3 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region AAA_25 PF13481.1 EKG14218.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EKG14218.1 - 0.093 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.22 EKG14218.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EKG14218.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 EKG14219.1 - 2.8e-31 108.8 0.0 2.5e-30 105.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG14219.1 - 0.0029 16.5 2.6 0.99 8.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EKG14219.1 - 0.14 10.7 0.4 1.4 7.4 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase HET PF06985.6 EKG14221.1 - 1.3e-22 80.4 0.1 3.4e-22 79.1 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Git3_C PF11970.3 EKG14222.1 - 0.0078 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EKG14222.1 - 0.15 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Rhodanese PF00581.15 EKG14223.1 - 3e-17 62.9 0.0 7.7e-17 61.6 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain KH_1 PF00013.24 EKG14224.1 - 9.5e-30 102.0 5.9 1.6e-07 30.8 0.2 7.3 7 0 0 7 7 7 5 KH domain KH_3 PF13014.1 EKG14224.1 - 1.6e-23 81.8 6.6 3.8e-05 23.2 0.0 6.2 6 0 0 6 6 6 4 KH domain Sds3 PF08598.6 EKG14225.1 - 2.1 7.8 8.8 0.31 10.5 3.3 1.7 2 0 0 2 2 2 0 Sds3-like HAD_2 PF13419.1 EKG14226.1 - 5e-34 118.0 0.2 6e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG14226.1 - 1.2e-08 35.6 0.0 1.1e-07 32.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG14226.1 - 3.9e-08 32.8 0.0 6.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EKG14226.1 - 0.02 14.5 0.1 0.078 12.6 0.1 1.9 1 1 0 1 1 1 0 Acid Phosphatase DUF575 PF04746.7 EKG14226.1 - 0.067 13.2 0.0 1.2 9.1 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF575) HAD PF12710.2 EKG14226.1 - 0.14 12.2 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase BSP PF04450.7 EKG14227.1 - 4e-77 258.3 0.0 4.7e-77 258.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EKG14227.1 - 1.7e-07 31.3 1.5 1.7e-06 28.1 1.1 2.1 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EKG14227.1 - 5.3e-05 22.9 0.1 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 SprT-like family CLASP_N PF12348.3 EKG14228.1 - 6e-122 405.2 0.4 1.5e-79 266.5 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EKG14228.1 - 5.4e-08 32.2 1.0 0.27 11.4 0.0 5.3 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EKG14228.1 - 1.3e-05 25.4 0.1 0.0059 16.8 0.0 4.1 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EKG14228.1 - 0.036 14.5 0.2 12 6.5 0.1 3.5 2 0 0 2 2 2 0 HEAT-like repeat Adaptin_N PF01602.15 EKG14228.1 - 0.078 11.2 0.2 0.33 9.2 0.0 2.1 3 0 0 3 3 3 0 Adaptin N terminal region RhoGAP PF00620.22 EKG14230.1 - 9e-48 161.7 0.3 4.9e-47 159.3 0.0 2.3 2 1 0 2 2 2 1 RhoGAP domain TMF_TATA_bd PF12325.3 EKG14230.1 - 0.02 14.6 20.9 0.085 12.5 3.4 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.2 EKG14230.1 - 0.055 13.3 20.7 0.016 15.0 3.0 2.9 3 0 0 3 3 3 0 Tropomyosin like Seryl_tRNA_N PF02403.17 EKG14230.1 - 0.23 11.4 19.1 0.15 12.0 3.9 3.6 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ZapA PF05164.8 EKG14230.1 - 0.63 10.0 10.0 0.26 11.2 3.4 2.9 2 1 0 2 2 2 0 Cell division protein ZapA Occludin_ELL PF07303.8 EKG14230.1 - 1.4 9.7 12.9 0.31 11.7 1.3 2.9 1 1 0 2 2 2 0 Occludin homology domain DUF904 PF06005.7 EKG14230.1 - 4.5 7.6 17.4 0.64 10.3 2.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Reo_sigmaC PF04582.7 EKG14230.1 - 7.7 5.5 8.5 3.8 6.6 1.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIC PF04977.10 EKG14230.1 - 8 6.0 18.9 0.53 9.7 0.7 3.8 2 2 2 4 4 4 0 Septum formation initiator APH PF01636.18 EKG14231.1 - 8.9e-05 22.3 0.1 0.00013 21.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family CENP-L PF13092.1 EKG14232.1 - 1.2e-25 90.1 0.0 1.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Iso_dh PF00180.15 EKG14233.1 - 3e-100 335.5 0.0 3.4e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 EKG14233.1 - 0.069 13.0 0.1 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sec5 PF15469.1 EKG14234.1 - 4.9e-36 124.1 0.0 1.5e-35 122.6 0.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.6 EKG14234.1 - 0.00013 21.7 0.1 0.0006 19.5 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 Cupin_2 PF07883.6 EKG14235.1 - 2.9e-13 49.0 0.0 5.3e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EKG14235.1 - 5.4e-09 35.8 0.0 9.8e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EKG14235.1 - 0.0027 17.3 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_1 PF00190.17 EKG14235.1 - 0.0081 15.6 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EKG14235.1 - 0.04 13.5 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Cupin Pyr_redox_3 PF13738.1 EKG14236.1 - 5.6e-18 65.7 0.0 8.4e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG14236.1 - 2e-09 36.1 0.1 1.5e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EKG14236.1 - 1e-08 35.3 0.0 0.0014 18.5 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG14236.1 - 2.6e-08 33.1 0.0 3.7e-05 22.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EKG14236.1 - 4.2e-07 29.8 0.1 4.1e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG14236.1 - 3.9e-05 23.4 0.3 0.033 13.9 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EKG14236.1 - 0.0093 16.3 0.0 1.3 9.4 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG14236.1 - 0.01 14.8 0.0 0.2 10.5 0.0 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EKG14236.1 - 0.051 12.4 0.0 0.13 11.0 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EKG14236.1 - 0.076 12.1 0.0 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EKG14236.1 - 0.099 12.2 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EKG14236.1 - 0.1 11.6 0.9 0.24 10.4 0.0 1.9 3 0 0 3 3 3 0 Thi4 family DAO PF01266.19 EKG14236.1 - 0.12 11.2 1.0 17 4.1 0.0 3.1 3 1 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EKG14236.1 - 0.14 12.2 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EKG14236.1 - 0.15 12.3 0.0 35 4.7 0.0 2.8 3 0 0 3 3 3 0 Putative NAD(P)-binding Malic_M PF03949.10 EKG14236.1 - 0.21 11.1 0.2 7 6.1 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain DUF3974 PF13120.1 EKG14237.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) p450 PF00067.17 EKG14239.1 - 2.7e-53 181.1 0.0 3.8e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SIR2 PF02146.12 EKG14240.1 - 5.1e-39 133.8 0.0 7.4e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Sir2 family ACP_syn_III_C PF08541.5 EKG14240.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF4330 PF14221.1 EKG14241.1 - 0.037 13.8 0.7 0.037 13.8 0.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4330) PEPCK PF00821.13 EKG14242.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase MFS_1 PF07690.11 EKG14243.1 - 5.5e-29 100.9 38.9 2.2e-28 98.9 27.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily 2-oxoacid_dh PF00198.18 EKG14244.1 - 1.3e-75 253.6 0.2 1.7e-75 253.2 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EKG14244.1 - 2.3e-17 62.4 1.9 2.3e-17 62.4 1.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EKG14244.1 - 1e-14 53.8 0.4 2.8e-14 52.4 0.3 1.9 1 0 0 1 1 1 1 e3 binding domain Sec7 PF01369.15 EKG14245.1 - 3.2e-64 216.1 0.2 3.2e-64 216.1 0.2 3.1 4 0 0 4 4 4 1 Sec7 domain Sec7_N PF12783.2 EKG14245.1 - 3.2e-54 182.8 3.1 3.2e-54 182.8 2.1 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EKG14245.1 - 3.5e-32 109.7 1.4 1.9e-30 104.2 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) But2 PF09792.4 EKG14246.1 - 1.4e-41 141.5 0.0 1.4e-41 141.5 0.0 2.4 2 1 1 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain UPF0506 PF11703.3 EKG14248.1 - 0.12 12.3 23.9 0.94 9.4 2.8 3.1 1 1 0 2 2 2 0 UPF0506 Oxidored_molyb PF00174.14 EKG14250.1 - 4.4e-46 156.3 0.0 8.4e-46 155.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EKG14250.1 - 9.4e-38 128.8 0.1 1.7e-37 127.9 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EKG14250.1 - 2.3e-15 56.1 0.1 5.7e-15 54.8 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.19 EKG14250.1 - 0.00021 21.3 0.0 0.00097 19.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain COesterase PF00135.23 EKG14251.1 - 7.1e-84 282.4 0.0 8.6e-84 282.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG14251.1 - 4.7e-06 26.3 0.2 1.6e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG14251.1 - 0.00036 19.8 0.2 0.00083 18.6 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG14251.1 - 0.06 13.1 0.1 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_10 PF12846.2 EKG14252.1 - 8.6e-06 25.4 0.3 0.025 14.0 0.0 2.1 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EKG14252.1 - 0.0044 17.1 0.0 2.4 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Roughex PF06020.6 EKG14252.1 - 0.19 10.3 2.2 0.34 9.5 1.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Fungal_trans PF04082.13 EKG14254.1 - 2.4e-14 52.8 0.2 4.1e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG14254.1 - 6.3e-07 29.1 13.1 6.3e-07 29.1 9.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VRP1 PF03538.9 EKG14254.1 - 0.064 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein DHDPS PF00701.17 EKG14255.1 - 3.1e-41 140.8 0.0 3.8e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HET PF06985.6 EKG14257.1 - 2.6e-27 95.6 0.0 4.7e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cyclin_N PF00134.18 EKG14258.1 - 7.6e-07 28.7 0.1 3.1e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain RRM_6 PF14259.1 EKG14259.1 - 5.5e-12 45.4 0.8 2e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG14259.1 - 7.8e-09 35.0 0.2 1.8e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG14259.1 - 7.6e-07 28.8 0.1 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EKG14259.1 - 4.7e-06 26.6 0.1 1.2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.1 EKG14259.1 - 0.0021 17.7 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EKG14259.1 - 0.029 14.0 1.6 0.053 13.2 1.1 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1330 PF07045.6 EKG14259.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) IncFII_repA PF02387.10 EKG14259.1 - 0.24 10.5 3.7 0.38 9.8 2.6 1.2 1 0 0 1 1 1 0 IncFII RepA protein family Caudo_TAP PF02413.12 EKG14259.1 - 1.5 8.9 11.3 0.057 13.5 3.6 1.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein AAA_13 PF13166.1 EKG14259.1 - 6.5 5.0 16.3 11 4.3 11.3 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EKG14260.1 - 1.7e-62 210.2 0.1 2.3e-62 209.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EKG14260.1 - 1.4e-38 131.0 0.0 4e-38 129.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EKG14260.1 - 6.6e-21 73.9 0.0 1.8e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EKG14260.1 - 2.2e-13 50.1 0.9 1.5e-12 47.4 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EKG14260.1 - 7.9e-12 44.8 0.0 1.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EKG14260.1 - 3.7e-06 26.8 0.1 6.9e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Amidohydro_2 PF04909.9 EKG14261.1 - 1.8e-16 60.5 0.0 1.4e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase AMP-binding PF00501.23 EKG14262.1 - 9.3e-13 47.3 0.0 1e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Macro PF01661.16 EKG14263.1 - 1.9e-40 137.4 0.3 7.6e-40 135.4 0.1 2.0 2 0 0 2 2 2 1 Macro domain Phosphoprotein PF00922.12 EKG14263.1 - 0.39 9.8 6.7 0.63 9.2 4.6 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Methyltransf_23 PF13489.1 EKG14264.1 - 0.00047 19.9 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG14264.1 - 0.0022 18.5 0.0 0.0053 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EKG14264.1 - 0.049 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EKG14264.1 - 0.091 12.2 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.1 EKG14264.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cerato-platanin PF07249.7 EKG14265.1 - 2.4e-05 24.3 0.6 6.3e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 Cerato-platanin DPBB_1 PF03330.13 EKG14265.1 - 0.00068 19.5 0.0 0.0021 18.0 0.0 1.9 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Mo-co_dimer PF03404.11 EKG14265.1 - 0.0069 16.0 0.2 0.012 15.2 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Pollen_allerg_1 PF01357.16 EKG14265.1 - 0.0071 16.1 3.1 0.0089 15.8 1.4 1.7 2 0 0 2 2 2 1 Pollen allergen BNR PF02012.15 EKG14265.1 - 0.082 12.7 0.6 0.74 9.8 0.0 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat HAD_2 PF13419.1 EKG14268.1 - 1.1e-11 45.3 0.0 2.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG14268.1 - 0.00015 21.4 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 EKG14268.1 - 0.044 12.7 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Prenyltrans_2 PF13249.1 EKG14268.1 - 0.044 14.1 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Prenyltransferase-like FAD_binding_4 PF01565.18 EKG14269.1 - 4.4e-24 84.5 0.0 2.8e-21 75.4 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain RPE65 PF03055.10 EKG14270.1 - 1.2e-117 393.4 0.3 1.3e-117 393.3 0.2 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein p450 PF00067.17 EKG14271.1 - 1.7e-41 142.2 0.0 2.1e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG14272.1 - 2.1e-34 118.8 0.0 2.4e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG14273.1 - 5.9e-11 41.5 0.0 8.5e-11 41.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1404 PF07185.6 EKG14273.1 - 0.062 12.8 1.2 9.1 5.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1404) ToxN_toxin PF13958.1 EKG14273.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system BRI3BP PF14965.1 EKG14273.1 - 0.097 12.0 0.2 0.17 11.2 0.1 1.5 2 0 0 2 2 2 0 Negative regulator of p53/TP53 AcetylCoA_hydro PF02550.10 EKG14275.1 - 1.7e-50 171.5 0.0 2.6e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EKG14275.1 - 8.9e-40 135.8 0.0 1.5e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Whi5 PF08528.6 EKG14276.1 - 2.7e-11 42.7 0.0 4.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Whi5 like DUF663 PF04950.7 EKG14277.1 - 3e-91 305.5 0.0 7.2e-91 304.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EKG14277.1 - 7.3e-26 89.5 0.0 6.2e-25 86.5 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EKG14277.1 - 7e-07 28.8 0.0 0.00016 21.1 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EKG14277.1 - 5.1e-05 23.3 0.0 0.00015 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EKG14277.1 - 0.00013 21.7 0.1 0.00036 20.2 0.1 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EKG14277.1 - 0.00014 21.7 0.0 0.00055 19.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EKG14277.1 - 0.00022 21.0 0.0 0.00077 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKG14277.1 - 0.00028 21.0 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG14277.1 - 0.00034 20.7 0.0 0.0011 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG14277.1 - 0.00052 20.8 0.0 0.00052 20.8 0.0 4.7 4 1 0 5 5 3 1 AAA domain NACHT PF05729.7 EKG14277.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 EKG14277.1 - 0.0018 18.5 1.3 0.0052 17.0 0.0 2.4 2 0 0 2 2 1 1 ABC transporter Miro PF08477.8 EKG14277.1 - 0.0023 18.4 0.2 0.008 16.6 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_19 PF13245.1 EKG14277.1 - 0.0071 16.0 0.2 0.0071 16.0 0.1 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 EKG14277.1 - 0.0091 15.4 0.0 0.028 13.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EKG14277.1 - 0.0091 15.7 0.2 0.022 14.4 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_24 PF13479.1 EKG14277.1 - 0.0094 15.5 0.1 0.023 14.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EKG14277.1 - 0.011 14.5 0.0 0.024 13.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 EKG14277.1 - 0.014 14.9 0.1 0.068 12.6 0.0 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EKG14277.1 - 0.016 14.6 0.1 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 EKG14277.1 - 0.018 15.2 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EKG14277.1 - 0.019 14.1 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EKG14277.1 - 0.021 14.7 0.0 0.052 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EKG14277.1 - 0.036 13.0 0.0 0.075 12.0 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_18 PF13238.1 EKG14277.1 - 0.037 14.3 0.0 0.037 14.3 0.0 3.8 5 1 0 5 5 2 0 AAA domain AAA_5 PF07728.9 EKG14277.1 - 0.059 13.0 1.5 0.16 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EKG14277.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EKG14277.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Inhibitor_I9 PF05922.11 EKG14278.1 - 1.2e-07 32.1 0.2 1.5e-07 31.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ribosomal_L12 PF00542.14 EKG14278.1 - 0.016 15.2 0.4 0.025 14.5 0.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain ABC_tran PF00005.22 EKG14280.1 - 4.1e-47 159.9 0.6 9.7e-24 84.2 0.0 4.0 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EKG14280.1 - 7.9e-17 62.1 0.0 0.0018 18.2 0.1 4.5 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EKG14280.1 - 9.7e-16 57.6 0.1 1e-05 24.9 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKG14280.1 - 3.7e-09 35.9 0.0 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 EKG14280.1 - 6.2e-08 32.7 0.1 0.0047 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EKG14280.1 - 6.6e-08 33.1 9.1 0.0035 17.7 2.1 3.7 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EKG14280.1 - 1e-07 32.7 0.0 0.0031 18.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKG14280.1 - 1.2e-07 31.9 0.0 0.0016 18.5 0.0 3.5 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 EKG14280.1 - 1.3e-06 27.7 0.1 0.00076 18.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EKG14280.1 - 2.4e-06 27.1 0.1 0.077 12.4 0.0 3.2 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EKG14280.1 - 2.4e-06 27.7 0.0 0.09 12.9 0.1 4.3 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EKG14280.1 - 2.9e-06 26.9 0.1 0.32 10.3 0.0 3.7 4 1 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EKG14280.1 - 5e-06 26.3 0.0 0.045 13.6 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 EKG14280.1 - 7.3e-06 25.9 0.0 0.003 17.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EKG14280.1 - 1.4e-05 25.5 0.0 0.027 14.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EKG14280.1 - 1.5e-05 25.3 0.3 0.19 12.0 0.0 3.5 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EKG14280.1 - 1.8e-05 24.5 0.0 0.056 13.1 0.0 3.1 2 0 0 2 2 2 2 Archaeal ATPase MMR_HSR1 PF01926.18 EKG14280.1 - 2e-05 24.4 0.0 0.02 14.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EKG14280.1 - 3.6e-05 23.6 0.1 0.28 11.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 EKG14280.1 - 3.7e-05 23.6 0.0 0.25 11.2 0.0 3.9 4 1 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EKG14280.1 - 4.3e-05 23.5 3.3 0.29 11.1 0.1 4.3 4 1 0 4 4 4 2 AAA ATPase domain NACHT PF05729.7 EKG14280.1 - 5.9e-05 22.7 0.1 0.064 12.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 EKG14280.1 - 7.1e-05 22.9 0.0 0.62 10.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 EKG14280.1 - 7.2e-05 21.6 0.1 0.062 12.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 EKG14280.1 - 0.0001 22.0 0.0 0.65 9.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B HEAT_2 PF13646.1 EKG14280.1 - 0.00019 21.6 8.9 0.1 12.8 0.0 4.1 1 1 4 5 5 5 2 HEAT repeats AAA_13 PF13166.1 EKG14280.1 - 0.0002 19.9 7.1 0.35 9.2 0.0 4.5 4 1 1 5 5 5 2 AAA domain cobW PF02492.14 EKG14280.1 - 0.00053 19.4 0.0 0.19 11.1 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ParcG PF10274.4 EKG14280.1 - 0.00054 19.9 1.7 2.4 8.0 0.0 3.9 2 1 2 4 4 4 1 Parkin co-regulated protein AAA_15 PF13175.1 EKG14280.1 - 0.00093 18.3 5.2 1.4 7.9 0.0 4.6 3 2 2 5 5 5 1 AAA ATPase domain AAA_30 PF13604.1 EKG14280.1 - 0.0012 18.4 0.0 1.7 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EKG14280.1 - 0.0039 16.9 0.1 5.6 6.7 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain ATP-synt_ab PF00006.20 EKG14280.1 - 0.0041 16.6 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 EKG14280.1 - 0.0051 16.3 0.0 3.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 EKG14280.1 - 0.0065 15.8 0.0 5.2 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EKG14280.1 - 0.0075 15.4 0.0 3.1 6.9 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EKG14280.1 - 0.011 14.6 0.1 3.3 6.5 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 EKG14280.1 - 0.016 15.0 7.3 0.21 11.3 0.0 4.1 5 0 0 5 5 3 0 Domain of unknown function DUF87 Septin PF00735.13 EKG14280.1 - 0.017 14.1 0.1 2.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Septin Adaptin_N PF01602.15 EKG14280.1 - 0.018 13.3 0.5 0.089 11.0 0.0 1.9 1 1 1 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.2 EKG14280.1 - 0.022 14.6 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 NB-ARC PF00931.17 EKG14280.1 - 0.022 13.5 0.0 0.31 9.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EKG14280.1 - 0.03 14.0 0.0 8.2 6.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EKG14280.1 - 0.049 13.2 0.1 4.9 6.7 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EKG14280.1 - 0.05 13.0 0.2 2.8 7.3 0.0 2.9 3 0 0 3 3 2 0 FtsK/SpoIIIE family PAS_11 PF14598.1 EKG14280.1 - 0.056 13.4 0.3 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 PAS domain AAA_24 PF13479.1 EKG14280.1 - 0.058 12.9 0.8 11 5.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 EKG14280.1 - 0.074 12.4 0.3 7.3 5.9 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain HEAT PF02985.17 EKG14280.1 - 1.4 9.2 3.5 11 6.4 0.0 3.6 4 0 0 4 4 2 0 HEAT repeat HEAT_EZ PF13513.1 EKG14280.1 - 3 8.4 8.4 1.3e+02 3.2 0.0 5.4 5 1 0 6 6 4 0 HEAT-like repeat Med21 PF11221.3 EKG14282.1 - 1.3e-31 109.5 0.0 1.4e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EKG14282.1 - 0.014 15.0 0.7 0.028 14.1 0.5 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2365 PF10157.4 EKG14282.1 - 0.52 10.1 4.0 24 4.8 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2365) DUF2034 PF10356.4 EKG14283.1 - 1.8e-30 105.4 0.1 2.5e-17 62.6 0.0 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EKG14283.1 - 3.7e-09 36.3 0.0 6.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease AT_hook PF02178.14 EKG14283.1 - 0.2 11.4 7.9 0.62 9.9 5.5 1.9 1 0 0 1 1 1 0 AT hook motif MutL_C PF08676.6 EKG14284.1 - 1.3e-22 79.9 0.0 5.4e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EKG14284.1 - 2.3e-20 72.2 0.0 5e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Aldedh PF00171.17 EKG14285.1 - 4e-87 292.4 0.0 4.7e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DAO PF01266.19 EKG14286.1 - 4.9e-11 42.1 0.0 5e-11 42.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG14286.1 - 1.9e-07 30.9 0.0 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG14286.1 - 6e-05 23.1 0.0 6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EKG14286.1 - 0.00024 21.0 0.0 0.00028 20.8 0.0 1.1 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 EKG14286.1 - 0.00029 20.0 0.0 0.00031 19.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EKG14286.1 - 0.00065 18.6 0.0 0.00071 18.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EKG14286.1 - 0.0011 18.7 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 ThiF family NAD_binding_9 PF13454.1 EKG14286.1 - 0.0012 18.6 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG14286.1 - 0.0018 18.1 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG14286.1 - 0.002 17.2 0.0 0.002 17.2 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EKG14286.1 - 0.0037 17.6 0.0 0.0042 17.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EKG14286.1 - 0.0051 16.2 0.0 0.0054 16.1 0.0 1.1 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EKG14286.1 - 0.0076 16.4 0.0 0.0085 16.3 0.0 1.0 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EKG14286.1 - 0.011 15.8 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EKG14286.1 - 0.013 13.9 0.0 0.016 13.7 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EKG14286.1 - 0.014 14.3 0.0 0.015 14.2 0.0 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 EKG14286.1 - 0.017 14.0 0.1 0.025 13.5 0.0 1.2 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.14 EKG14286.1 - 0.046 12.8 0.0 0.049 12.7 0.0 1.0 1 0 0 1 1 1 0 GMC oxidoreductase Amino_oxidase PF01593.19 EKG14286.1 - 0.064 12.3 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EKG14286.1 - 0.075 12.6 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EKG14286.1 - 0.082 12.6 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus adh_short PF00106.20 EKG14286.1 - 0.094 12.6 0.0 0.11 12.4 0.0 1.0 1 0 0 1 1 1 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.9 EKG14286.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 EKG14286.1 - 0.12 11.0 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Herpes_LP PF03363.8 EKG14287.1 - 0.54 9.8 4.9 0.37 10.3 2.2 1.5 1 1 0 1 1 1 0 Herpesvirus leader protein DivIC PF04977.10 EKG14290.1 - 0.0061 16.0 0.3 0.015 14.7 0.2 1.6 1 0 0 1 1 1 1 Septum formation initiator HALZ PF02183.13 EKG14290.1 - 0.027 14.2 0.2 0.05 13.3 0.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EKG14290.1 - 0.046 13.5 0.4 0.093 12.5 0.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Cep57_CLD_2 PF14197.1 EKG14290.1 - 0.079 12.9 1.0 0.2 11.6 0.7 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 GFA PF04828.9 EKG14292.1 - 1.8e-13 50.2 0.0 2.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EKG14292.1 - 0.023 14.2 0.7 0.037 13.5 0.5 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 EKG14292.1 - 0.04 13.5 0.3 0.074 12.7 0.2 1.4 1 0 0 1 1 1 0 Nudix N-terminal zf-ribbon_3 PF13248.1 EKG14292.1 - 0.049 12.8 0.1 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain ADH_N PF08240.7 EKG14293.1 - 4.8e-20 71.3 0.2 8.5e-20 70.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG14293.1 - 1.3e-18 66.8 0.2 2.1e-18 66.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EKG14293.1 - 4e-05 23.2 0.2 7e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EKG14293.1 - 0.00075 19.4 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_18 PF12847.2 EKG14293.1 - 0.0017 18.8 0.0 0.0031 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CoA_binding_2 PF13380.1 EKG14293.1 - 0.004 17.3 0.1 0.0072 16.4 0.1 1.3 1 0 0 1 1 1 1 CoA binding domain 3HCDH_N PF02737.13 EKG14293.1 - 0.009 15.6 0.2 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EKG14293.1 - 0.014 14.8 0.1 0.022 14.1 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EKG14293.1 - 0.023 13.8 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EKG14293.1 - 0.035 14.2 0.1 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cytochrome_CBB3 PF13442.1 EKG14293.1 - 0.12 12.5 0.9 0.27 11.4 0.6 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AOX PF01786.12 EKG14294.1 - 0.11 11.8 1.2 8.7 5.6 0.9 2.2 2 0 0 2 2 2 0 Alternative oxidase DUF2235 PF09994.4 EKG14295.1 - 2.2e-61 207.6 5.9 1e-60 205.5 0.1 2.8 2 1 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Aa_trans PF01490.13 EKG14296.1 - 2.2e-33 115.3 31.3 2.8e-33 115.0 21.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein P5CR_dimer PF14748.1 EKG14298.1 - 4.6e-30 103.7 1.0 4.6e-30 103.7 0.7 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EKG14298.1 - 2.7e-11 43.7 0.0 6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EKG14298.1 - 0.057 13.2 0.2 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 ThiF family Macoilin PF09726.4 EKG14299.1 - 0.034 12.4 3.6 0.037 12.3 2.5 1.0 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 EKG14302.1 - 3e-40 134.6 12.7 1.3e-11 43.8 0.1 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EKG14302.1 - 4.3e-09 35.0 4.1 0.04 12.0 0.1 4.9 1 1 3 4 4 4 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EKG14302.1 - 0.0011 18.7 0.1 0.0064 16.2 0.0 2.3 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region TruB_C PF09142.6 EKG14302.1 - 0.015 14.9 0.1 0.051 13.2 0.1 2.1 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal PQQ_3 PF13570.1 EKG14302.1 - 0.024 14.9 5.4 1.2 9.4 0.1 4.2 3 2 1 4 4 4 0 PQQ-like domain DUF3328 PF11807.3 EKG14304.1 - 6.3e-50 169.8 0.2 7.5e-50 169.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4035 PF13227.1 EKG14305.1 - 5.7e-08 32.0 1.3 46 3.4 0.0 9.0 1 1 11 12 12 12 0 Protein of unknown function (DUF4035) Nbs1_C PF08599.5 EKG14305.1 - 0.00011 21.9 36.5 26 4.8 0.0 11.4 12 0 0 12 12 12 0 DNA damage repair protein Nbs1 THP2 PF09432.5 EKG14305.1 - 0.00024 20.9 12.1 3.7 7.4 0.2 5.5 1 1 5 6 6 6 3 Tho complex subunit THP2 Pro_dh-DNA_bdg PF14850.1 EKG14305.1 - 0.0026 17.9 9.0 53 4.0 0.0 5.7 1 1 6 7 7 7 0 DNA-binding domain of Proline dehydrogenase Peptidase_C47 PF05543.8 EKG14305.1 - 0.013 14.9 0.0 31 3.9 0.0 4.3 1 1 5 6 6 6 0 Staphopain peptidase C47 DUF3113 PF11310.3 EKG14305.1 - 0.072 12.7 16.5 27 4.5 0.3 7.4 1 1 6 7 7 7 0 Protein of unknown function (DUF3113) DUF445 PF04286.7 EKG14305.1 - 0.36 10.3 7.7 1.1 8.7 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF2336 PF10098.4 EKG14305.1 - 0.39 9.9 4.3 4.4 6.4 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2336) MAM33 PF02330.11 EKG14305.1 - 0.46 10.2 12.5 4.3 7.0 0.4 4.4 1 1 5 6 6 6 0 Mitochondrial glycoprotein CRISPR_Cas2 PF09827.4 EKG14305.1 - 1.3 9.1 4.6 1.1e+02 3.0 0.0 5.1 2 2 1 4 4 4 0 CRISPR associated protein Cas2 ABC_tran PF00005.22 EKG14306.1 - 8.5e-46 155.6 0.0 2e-24 86.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKG14306.1 - 8.5e-40 136.8 9.8 3.1e-26 92.3 2.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EKG14306.1 - 8.7e-18 65.2 0.0 4.1e-05 23.6 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EKG14306.1 - 9e-14 51.2 0.8 0.0039 16.4 0.0 4.9 4 1 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EKG14306.1 - 5.3e-10 39.5 0.1 0.0018 18.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKG14306.1 - 2.1e-09 37.6 1.6 0.00079 19.4 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EKG14306.1 - 6.2e-09 35.2 0.1 0.002 17.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EKG14306.1 - 7.5e-08 32.0 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 EKG14306.1 - 5.7e-07 29.2 0.2 0.032 13.6 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 EKG14306.1 - 2.1e-06 27.2 0.1 0.0019 17.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 EKG14306.1 - 1e-05 24.8 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG14306.1 - 1.1e-05 26.2 0.0 0.073 13.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EKG14306.1 - 1.6e-05 25.3 0.0 0.057 13.9 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 EKG14306.1 - 2.8e-05 24.5 0.0 0.028 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKG14306.1 - 2.8e-05 23.9 0.0 0.041 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EKG14306.1 - 4e-05 22.6 0.0 0.021 13.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EKG14306.1 - 5.7e-05 22.7 0.0 0.19 11.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EKG14306.1 - 8.5e-05 22.2 0.0 0.097 12.3 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EKG14306.1 - 0.00014 21.5 0.0 0.0018 18.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EKG14306.1 - 0.00018 21.2 0.1 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EKG14306.1 - 0.00018 21.4 0.2 0.032 14.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EKG14306.1 - 0.00054 20.2 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.7 EKG14306.1 - 0.0011 18.2 0.0 0.33 10.2 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Arch_ATPase PF01637.13 EKG14306.1 - 0.0012 18.6 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EKG14306.1 - 0.0012 18.7 0.0 0.43 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 EKG14306.1 - 0.0018 17.7 0.3 0.15 11.5 0.1 2.6 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 EKG14306.1 - 0.0024 17.5 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKG14306.1 - 0.0026 17.7 0.0 0.31 11.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EKG14306.1 - 0.0033 17.5 0.1 2.5 8.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase NTPase_1 PF03266.10 EKG14306.1 - 0.0062 16.2 0.0 1.3 8.6 0.1 2.5 2 0 0 2 2 2 1 NTPase PRK PF00485.13 EKG14306.1 - 0.0065 16.0 0.1 2.9 7.4 0.1 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Septin PF00735.13 EKG14306.1 - 0.0088 15.0 0.0 2 7.3 0.0 2.2 2 0 0 2 2 2 1 Septin SbcCD_C PF13558.1 EKG14306.1 - 0.009 15.9 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.1 EKG14306.1 - 0.011 14.3 0.0 1.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) KaiC PF06745.8 EKG14306.1 - 0.012 14.7 0.1 0.5 9.4 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.1 EKG14306.1 - 0.022 14.3 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EKG14306.1 - 0.023 13.8 0.0 0.27 10.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKG14306.1 - 0.038 13.7 0.2 11 5.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EKG14306.1 - 0.046 12.6 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EKG14306.1 - 0.05 13.8 0.1 1.4 9.0 0.0 3.1 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EKG14306.1 - 0.07 12.6 0.3 2 7.9 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 EKG14306.1 - 0.078 11.8 0.3 23 3.7 0.4 3.1 2 1 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 EKG14306.1 - 0.099 12.6 0.3 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EKG14306.1 - 0.11 11.9 0.1 3.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.4 EKG14306.1 - 0.14 10.7 0.0 14 4.1 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA12 PF10443.4 EKG14306.1 - 0.29 9.5 0.0 0.8 8.1 0.0 1.6 2 0 0 2 2 2 0 RNA12 protein Dynamin_N PF00350.18 EKG14306.1 - 0.31 10.8 6.8 0.53 10.0 0.1 2.5 3 0 0 3 3 2 0 Dynamin family IstB_IS21 PF01695.12 EKG14306.1 - 0.52 9.6 3.3 18 4.6 0.0 3.6 5 0 0 5 5 3 0 IstB-like ATP binding protein AA_permease PF00324.16 EKG14307.1 - 9.8e-127 423.1 48.1 1.1e-126 423.0 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG14307.1 - 8.1e-32 110.2 53.3 1e-31 109.9 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EKG14307.1 - 0.098 12.2 0.3 0.31 10.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Phage_Gp23 PF10669.4 EKG14307.1 - 0.22 11.6 0.8 0.95 9.5 0.3 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Nudix_N_2 PF14803.1 EKG14308.1 - 0.31 10.7 3.0 0.17 11.6 0.2 2.0 2 0 0 2 2 2 0 Nudix N-terminal ADH_zinc_N PF00107.21 EKG14309.1 - 6.2e-25 87.2 0.9 1e-24 86.5 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG14309.1 - 5.9e-10 40.1 0.3 1.8e-09 38.5 0.0 2.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG14309.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Palm_thioest PF02089.10 EKG14310.1 - 1.9e-56 191.0 0.0 2.4e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 EKG14310.1 - 0.0051 15.9 0.0 0.0086 15.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 EKG14310.1 - 0.054 12.8 0.0 0.095 11.9 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 2) zinc-ribbons_6 PF07191.7 EKG14310.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbons HTH_18 PF12833.2 EKG14310.1 - 0.15 12.1 0.0 0.91 9.6 0.0 2.2 3 0 0 3 3 3 0 Helix-turn-helix domain Fungal_trans PF04082.13 EKG14311.1 - 4.4e-21 74.9 0.1 6.1e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG14311.1 - 2.6e-06 27.2 13.4 5.6e-06 26.1 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AsiA PF09010.5 EKG14311.1 - 0.0058 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Anti-Sigma Factor A MCM PF00493.18 EKG14312.1 - 6.9e-128 426.1 0.3 9.5e-128 425.6 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKG14312.1 - 4.6e-15 56.1 0.0 1.1e-14 54.8 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKG14312.1 - 7.8e-07 28.4 0.0 1e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKG14312.1 - 0.003 17.1 0.0 0.0076 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKG14312.1 - 0.073 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain SNF2_N PF00176.18 EKG14313.1 - 4.9e-70 235.6 0.0 6.8e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG14313.1 - 1.1e-09 38.0 0.0 2.5e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG14313.1 - 1.7e-05 24.3 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EKG14313.1 - 0.00054 19.6 3.0 0.0012 18.5 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKG14313.1 - 0.0035 17.1 0.3 0.0098 15.7 0.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKG14313.1 - 0.1 12.6 1.8 0.26 11.3 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG14313.1 - 0.48 10.1 3.2 0.29 10.8 0.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Arc_trans_TRASH PF08394.5 EKG14313.1 - 1.9 8.7 4.5 2.1 8.5 0.3 2.5 2 0 0 2 2 2 0 Archaeal TRASH domain PI3_PI4_kinase PF00454.22 EKG14314.1 - 5.3e-41 140.6 0.0 7.2e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Tropomyosin PF00261.15 EKG14315.1 - 0.0019 17.3 9.6 0.0022 17.1 6.7 1.0 1 0 0 1 1 1 1 Tropomyosin CENP-F_leu_zip PF10473.4 EKG14315.1 - 0.0022 17.8 10.7 0.21 11.4 2.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.4 EKG14315.1 - 0.0036 16.6 7.8 0.0045 16.2 5.4 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) BicD PF09730.4 EKG14315.1 - 0.0037 15.7 3.4 0.0039 15.6 2.4 1.3 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D zf-ZPR1 PF03367.8 EKG14315.1 - 0.008 15.3 1.0 0.015 14.4 0.7 1.6 1 1 0 1 1 1 1 ZPR1 zinc-finger domain Cortex-I_coil PF09304.5 EKG14315.1 - 0.0091 16.0 5.7 0.011 15.7 4.0 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil Rootletin PF15035.1 EKG14315.1 - 0.01 15.8 5.5 0.013 15.5 3.8 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Pox_A_type_inc PF04508.7 EKG14315.1 - 0.011 15.4 5.9 0.1 12.4 0.2 3.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ATG16 PF08614.6 EKG14315.1 - 0.011 15.6 5.6 0.014 15.1 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF904 PF06005.7 EKG14315.1 - 0.014 15.6 8.4 0.2 11.9 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) IncA PF04156.9 EKG14315.1 - 0.014 15.0 4.7 0.02 14.5 3.3 1.3 1 0 0 1 1 1 0 IncA protein Striatin PF08232.7 EKG14315.1 - 0.014 15.7 7.0 0.21 11.9 2.1 2.0 1 1 1 2 2 2 0 Striatin family Fmp27_WPPW PF10359.4 EKG14315.1 - 0.016 13.6 5.0 0.017 13.5 3.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain KLRAQ PF10205.4 EKG14315.1 - 0.023 14.7 8.0 0.059 13.4 5.7 1.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.4 EKG14315.1 - 0.024 13.6 4.8 0.028 13.3 3.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PspA_IM30 PF04012.7 EKG14315.1 - 0.044 13.1 7.4 0.11 11.8 4.5 1.8 1 1 1 2 2 2 0 PspA/IM30 family RILP PF11461.3 EKG14315.1 - 0.045 13.8 2.0 0.071 13.2 0.1 2.1 1 1 1 2 2 2 0 Rab interacting lysosomal protein Packaging_FI PF14000.1 EKG14315.1 - 0.059 13.5 7.9 0.053 13.7 1.4 2.1 1 1 1 2 2 2 0 DNA packaging protein FI APG6 PF04111.7 EKG14315.1 - 0.061 12.3 5.5 0.064 12.2 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EKG14315.1 - 0.069 12.3 5.4 0.087 12.0 3.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.4 EKG14315.1 - 0.12 10.6 4.8 0.13 10.5 3.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4094 PF13334.1 EKG14315.1 - 0.18 12.2 4.4 0.38 11.1 3.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) TMF_DNA_bd PF12329.3 EKG14315.1 - 0.19 11.5 9.9 0.22 11.3 5.9 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EKG14315.1 - 0.21 11.1 6.9 0.1 12.1 1.2 2.5 1 1 2 3 3 3 0 Septum formation initiator WD40_alt PF14077.1 EKG14315.1 - 0.24 11.0 8.5 5.9 6.6 0.6 3.4 2 1 1 3 3 3 0 Alternative WD40 repeat motif ADIP PF11559.3 EKG14315.1 - 0.3 10.9 9.1 1.1 9.1 6.5 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 EKG14315.1 - 0.3 11.0 10.8 1.2 9.0 7.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Nsp1_C PF05064.8 EKG14315.1 - 0.31 10.7 2.9 0.52 9.9 2.0 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region Herpes_UL25 PF01499.11 EKG14315.1 - 0.44 8.8 3.9 0.5 8.6 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4407 PF14362.1 EKG14315.1 - 0.54 9.1 3.1 0.62 8.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.10 EKG14315.1 - 0.66 9.9 10.5 1.9 8.4 7.3 1.6 1 1 0 1 1 1 0 Fez1 UPF0184 PF03670.8 EKG14315.1 - 0.7 10.1 6.4 12 6.1 0.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) IFP_35_N PF07334.8 EKG14315.1 - 0.85 9.6 3.2 1.4 8.8 0.4 2.4 1 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus SKIP_SNW PF02731.10 EKG14315.1 - 0.89 9.0 5.8 1.2 8.5 4.0 1.2 1 0 0 1 1 1 0 SKIP/SNW domain DivIVA PF05103.8 EKG14315.1 - 0.9 9.5 7.0 3.9 7.5 4.7 2.1 1 1 0 1 1 1 0 DivIVA protein SPX PF03105.14 EKG14315.1 - 0.91 9.2 5.5 7.2 6.3 3.8 1.9 1 1 0 1 1 1 0 SPX domain DUF972 PF06156.8 EKG14315.1 - 1.2 9.5 5.3 12 6.3 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CASP_C PF08172.7 EKG14315.1 - 1.7 7.5 8.7 1.5 7.7 2.3 2.2 1 1 0 2 2 2 0 CASP C terminal FUSC PF04632.7 EKG14315.1 - 1.8 6.8 3.5 1.8 6.8 2.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4164 PF13747.1 EKG14315.1 - 2.9 8.0 12.9 4.9 7.3 8.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) GrpE PF01025.14 EKG14315.1 - 3.6 7.1 8.1 6 6.3 5.4 1.5 1 1 1 2 2 2 0 GrpE Spc24 PF08286.6 EKG14315.1 - 4.4 7.0 7.3 6.9 6.3 4.4 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Pribosyltran_N PF13793.1 EKG14316.1 - 1.8e-42 143.7 0.0 7e-42 141.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EKG14316.1 - 9.6e-37 126.5 0.0 6.3e-31 107.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EKG14316.1 - 0.00011 21.8 0.0 0.012 15.3 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Acetyltransf_4 PF13420.1 EKG14317.1 - 4.9e-10 39.5 0.0 0.0014 18.6 0.4 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG14317.1 - 2.3e-05 24.3 0.2 0.00012 22.0 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EKG14317.1 - 0.00051 20.2 0.0 0.001 19.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG14317.1 - 0.0015 18.6 2.1 0.0018 18.3 0.0 2.3 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG14317.1 - 0.0034 17.5 0.3 0.012 15.7 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG14317.1 - 0.022 14.6 0.3 0.088 12.6 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.8 EKG14318.1 - 2e-55 187.6 0.0 2.4e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG14318.1 - 0.00029 20.6 0.1 0.00036 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EKG14318.1 - 0.001 18.3 0.2 0.0048 16.1 0.1 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EKG14318.1 - 0.0034 16.6 0.1 0.32 10.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EKG14318.1 - 0.01 14.5 0.3 0.054 12.2 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family DUF2424 PF10340.4 EKG14318.1 - 0.21 10.1 0.0 0.35 9.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) HSP70 PF00012.15 EKG14319.1 - 1e-166 555.4 0.6 1e-166 555.4 0.4 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EKG14319.1 - 3e-16 58.9 0.2 2.5e-13 49.3 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 EKG14319.1 - 1.4e-06 28.1 0.4 0.0073 16.1 0.0 3.5 3 0 0 3 3 3 2 Cell division protein FtsA Trans_reg_C PF00486.23 EKG14319.1 - 0.035 14.0 0.1 7.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal NPR3 PF03666.8 EKG14319.1 - 2.2 6.7 5.4 3.7 5.9 3.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BNR PF02012.15 EKG14322.1 - 0.035 13.8 0.0 0.2 11.6 0.0 2.4 1 0 0 1 1 1 0 BNR/Asp-box repeat SNF2_N PF00176.18 EKG14323.1 - 1.9e-67 227.1 0.0 4e-67 226.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG14323.1 - 1.8e-15 56.5 0.0 1.3e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EKG14323.1 - 7.4e-06 24.9 0.0 0.00015 20.6 0.0 2.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EKG14323.1 - 0.00015 21.6 0.4 0.014 15.1 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKG14323.1 - 0.0021 17.6 0.0 0.0045 16.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase End3 PF12761.2 EKG14324.1 - 8e-72 240.9 0.1 1.1e-71 240.4 0.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EKG14324.1 - 3.3e-53 177.8 0.0 5.6e-50 167.4 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EKG14324.1 - 5.1e-08 31.6 0.4 1.5e-07 30.2 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EKG14324.1 - 4.6e-07 29.3 0.2 2.3e-06 27.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EKG14324.1 - 1.4e-06 28.2 0.1 1.3e-05 25.2 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EKG14324.1 - 0.00015 21.3 0.3 0.00061 19.4 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EKG14324.1 - 0.0012 18.0 0.1 0.0034 16.6 0.1 1.8 1 0 0 1 1 1 1 EF hand COG2 PF06148.6 EKG14324.1 - 0.024 14.4 5.8 0.048 13.5 0.7 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 EKG14324.1 - 0.2 11.4 8.2 0.041 13.6 2.8 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SSFA2_C PF14723.1 EKG14324.1 - 0.47 10.1 5.2 12 5.6 3.6 2.2 1 1 0 1 1 1 0 Sperm-specific antigen 2 C-terminus AKNA PF12443.3 EKG14324.1 - 0.49 10.4 7.4 0.13 12.3 0.8 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor IFT57 PF10498.4 EKG14324.1 - 2.2 6.9 10.2 3.2 6.4 1.2 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 peroxidase PF00141.18 EKG14325.1 - 7.8e-23 81.1 0.1 1e-21 77.5 0.0 2.2 2 0 0 2 2 2 1 Peroxidase MFS_1 PF07690.11 EKG14327.1 - 1.2e-32 112.9 9.6 1.2e-32 112.9 6.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG14327.1 - 1.3e-14 53.6 0.7 1.3e-14 53.6 0.5 2.7 2 2 1 2 2 2 1 Sugar (and other) transporter DUF4131 PF13567.1 EKG14327.1 - 0.037 13.4 1.5 18 4.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) TPT PF03151.11 EKG14328.1 - 9e-26 90.3 7.9 9e-26 90.3 5.5 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EKG14328.1 - 1.2e-06 27.6 12.6 0.00012 21.0 1.8 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 EKG14328.1 - 0.0038 17.2 9.9 0.0038 17.2 6.9 2.4 3 0 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EKG14328.1 - 1.9 7.2 13.8 20 3.8 9.6 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) FAA_hydrolase PF01557.13 EKG14330.1 - 2.7e-10 40.0 0.5 2.9e-10 39.9 0.3 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 EKG14331.1 - 1.6e-10 40.3 0.0 3.1e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG14332.1 - 4.8e-11 41.9 10.4 5.8e-11 41.7 7.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 EKG14333.1 - 4.9e-32 110.9 1.0 7.8e-32 110.3 0.7 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chitin_synth_2 PF03142.10 EKG14334.1 - 8.5e-24 83.8 1.5 8.5e-24 83.8 1.0 3.0 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EKG14334.1 - 6e-16 58.7 2.6 6e-16 58.7 1.8 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG14334.1 - 1.2e-15 58.0 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EKG14334.1 - 0.0026 17.4 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Cellulase PF00150.13 EKG14335.1 - 6e-21 74.8 4.8 1e-20 74.1 3.3 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tautomerase_3 PF14832.1 EKG14337.1 - 3e-50 169.7 0.0 3.4e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EKG14337.1 - 0.001 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Tautomerase enzyme Ribosomal_S19e PF01090.14 EKG14338.1 - 1e-56 190.2 0.2 1.2e-56 190.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e SprT-like PF10263.4 EKG14339.1 - 0.0091 15.6 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 1 SprT-like family Mu-transpos_C PF09299.6 EKG14339.1 - 0.27 11.1 1.1 5.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Mu transposase, C-terminal Dioxygenase_C PF00775.16 EKG14344.1 - 1.5e-11 43.9 0.1 2.3e-10 40.0 0.1 2.5 1 1 0 1 1 1 1 Dioxygenase TPR_11 PF13414.1 EKG14345.1 - 1.1e-05 24.9 4.5 0.024 14.2 0.1 3.1 2 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EKG14345.1 - 0.00038 20.1 9.0 0.11 12.4 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG14345.1 - 0.0014 19.1 4.8 0.019 15.5 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKG14345.1 - 0.0056 16.5 2.4 3.4 7.6 0.2 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKG14345.1 - 0.0081 16.4 1.8 0.37 11.1 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKG14345.1 - 0.086 12.4 7.2 2.2 8.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 EKG14345.1 - 0.12 13.0 3.1 0.26 11.9 0.7 2.6 2 0 0 2 2 2 0 Sel1 repeat TPR_16 PF13432.1 EKG14345.1 - 0.25 12.0 11.1 2.3 8.9 0.6 3.6 3 1 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_2_N PF02837.13 EKG14347.1 - 2.3e-05 24.0 0.0 5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4210 PF13915.1 EKG14348.1 - 9.9e-26 89.8 0.0 2.1e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EKG14348.1 - 4.6e-22 77.6 0.7 1.2e-21 76.3 0.5 1.8 1 0 0 1 1 1 1 Chromosome segregation during meiosis Nop53 PF07767.6 EKG14349.1 - 0.047 12.6 28.4 0.089 11.7 19.7 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) rRNA_processing PF08524.6 EKG14349.1 - 0.22 11.2 37.6 3.1e+02 1.0 25.8 2.4 1 1 0 1 1 1 0 rRNA processing DUF4611 PF15387.1 EKG14349.1 - 3.4 7.8 13.7 0.056 13.5 3.8 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) Glyco_hydro_20 PF00728.17 EKG14350.1 - 1.3e-36 126.5 0.1 4.3e-36 124.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EKG14350.1 - 7.1e-10 39.4 0.0 1.4e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 CHCH PF06747.8 EKG14352.1 - 1.2e-06 28.2 5.2 2e-06 27.5 3.6 1.3 1 0 0 1 1 1 1 CHCH domain FancD2 PF14631.1 EKG14352.1 - 0.016 12.3 0.2 0.021 11.9 0.2 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Glyoxal_oxid_N PF07250.6 EKG14353.1 - 1.8e-29 102.5 0.0 1.1e-28 99.9 0.0 2.1 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EKG14353.1 - 8.7e-25 86.6 0.2 6.4e-24 83.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EKG14353.1 - 0.0025 17.5 0.0 3.3 7.5 0.0 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EKG14353.1 - 0.069 12.9 0.1 0.54 10.1 0.0 2.5 3 0 0 3 3 3 0 Kelch motif NACHT PF05729.7 EKG14354.1 - 4.5e-09 36.1 0.0 9.9e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 EKG14354.1 - 7.5e-05 22.3 0.0 0.85 9.5 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat AAA_22 PF13401.1 EKG14354.1 - 0.00054 20.1 0.0 0.0017 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKG14354.1 - 0.00057 19.4 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EKG14354.1 - 0.012 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EKG14354.1 - 0.015 16.1 0.2 0.29 11.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.1 EKG14354.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG14354.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ank_2 PF12796.2 EKG14354.1 - 0.034 14.4 0.0 0.094 13.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG14354.1 - 0.058 13.9 0.0 2.2 8.8 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_16 PF13191.1 EKG14354.1 - 0.08 12.9 0.1 0.44 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.9 EKG14354.1 - 0.1 11.5 0.1 2.4 7.0 0.1 2.2 1 1 0 1 1 1 0 KAP family P-loop domain Arch_ATPase PF01637.13 EKG14354.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 EKG14354.1 - 0.15 11.4 0.1 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EKG14354.1 - 0.18 11.5 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 NTPase Epimerase PF01370.16 EKG14355.1 - 8.4e-14 51.5 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG14355.1 - 3.8e-10 40.0 0.4 1.3e-09 38.3 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG14355.1 - 0.0016 17.1 0.0 0.0032 16.2 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EKG14355.1 - 0.0037 17.1 0.4 0.017 15.0 0.0 2.2 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EKG14355.1 - 0.024 13.5 0.0 0.093 11.6 0.0 1.9 2 0 0 2 2 2 0 Male sterility protein Pkr1 PF08636.5 EKG14356.1 - 0.052 13.6 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 ER protein Pkr1 DUF2298 PF10060.4 EKG14356.1 - 0.055 12.3 0.1 0.059 12.2 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) MFS_1 PF07690.11 EKG14357.1 - 2.1e-16 59.6 62.1 6.3e-11 41.5 26.3 2.6 2 1 2 4 4 4 3 Major Facilitator Superfamily DUF2976 PF11190.3 EKG14357.1 - 0.076 12.5 14.4 0.31 10.5 1.2 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2976) MFS_1 PF07690.11 EKG14358.1 - 1.5e-47 162.0 54.9 4.5e-37 127.5 27.1 3.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG14358.1 - 7.4e-18 64.0 28.4 1.5e-17 63.0 19.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG14358.1 - 9e-14 50.8 35.9 1.6e-13 50.0 9.9 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EKG14358.1 - 0.0025 17.5 3.6 0.014 15.1 0.0 3.1 2 1 0 2 2 2 1 MFS_1 like family p450 PF00067.17 EKG14359.1 - 1.3e-36 126.0 0.0 1.8e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EKG14361.1 - 9.7e-10 37.6 16.3 1.2e-09 37.3 10.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TIM-br_sig_trns PF09370.5 EKG14361.1 - 0.0045 16.0 0.2 0.036 13.1 0.0 2.0 2 0 0 2 2 2 1 TIM-barrel signal transduction protein AAA PF00004.24 EKG14363.1 - 8.9e-18 64.7 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG14363.1 - 0.00052 20.8 0.2 0.0035 18.1 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EKG14363.1 - 0.0026 17.7 1.1 0.011 15.6 0.4 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG14363.1 - 0.0036 17.4 1.0 0.018 15.1 0.1 2.5 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EKG14363.1 - 0.01 16.1 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKG14363.1 - 0.015 14.4 0.1 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EKG14363.1 - 0.036 13.8 0.1 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 EKG14363.1 - 0.047 13.5 0.0 0.17 11.7 0.0 1.9 1 1 1 2 2 2 0 Torsin AAA_5 PF07728.9 EKG14363.1 - 0.068 12.8 0.3 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EKG14363.1 - 0.097 11.7 0.0 2.7 7.0 0.1 2.2 2 0 0 2 2 2 0 KaiC Zot PF05707.7 EKG14363.1 - 0.11 11.9 0.3 6.3 6.2 0.0 2.6 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) DUF2075 PF09848.4 EKG14363.1 - 0.11 11.4 0.1 6.7 5.5 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.7 EKG14363.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein 2-Hacid_dh_C PF02826.14 EKG14364.1 - 1e-50 171.3 0.0 1.4e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG14364.1 - 4e-25 87.8 0.0 4.6e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EKG14364.1 - 1.8e-05 24.6 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EKG14364.1 - 0.0072 16.7 0.0 0.041 14.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EKG14364.1 - 0.027 14.4 0.1 0.087 12.8 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EKG14364.1 - 0.032 14.7 0.0 0.067 13.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EKG14364.1 - 0.046 14.0 0.0 3.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain IRS PF02174.12 EKG14365.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 PTB domain (IRS-1 type) MFS_1 PF07690.11 EKG14366.1 - 9.1e-19 67.3 16.8 1.1e-18 67.1 11.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG14366.1 - 0.027 13.0 8.4 0.039 12.5 5.8 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter adh_short PF00106.20 EKG14368.1 - 8.4e-27 94.1 0.1 1.2e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG14368.1 - 7.7e-14 52.0 0.0 9.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG14368.1 - 3.5e-09 36.5 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EKG14368.1 - 9.9e-06 24.8 0.0 2e-05 23.8 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EKG14368.1 - 7.5e-05 22.8 0.2 0.00064 19.7 0.1 2.1 2 0 0 2 2 2 1 NADH(P)-binding TrkA_N PF02254.13 EKG14368.1 - 0.095 12.7 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.10 EKG14368.1 - 0.095 12.5 0.1 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 EKG14368.1 - 0.1 12.2 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Glyco_hydro_62 PF03664.8 EKG14370.1 - 4.5e-75 252.2 1.4 5.1e-75 252.0 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Alpha_kinase PF02816.13 EKG14370.1 - 0.12 12.0 0.1 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-kinase family Peptidase_M43 PF05572.8 EKG14371.1 - 5.9e-13 48.6 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EKG14371.1 - 0.0013 18.7 0.1 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EKG14371.1 - 0.0052 16.3 0.5 0.015 14.8 0.1 1.9 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EKG14371.1 - 0.034 14.0 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 FAD_binding_4 PF01565.18 EKG14375.1 - 4.6e-21 74.7 1.0 1e-20 73.6 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EKG14375.1 - 2.6e-05 24.0 0.2 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_2 PF00890.19 EKG14376.1 - 1.7e-51 175.3 0.0 1.8e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EKG14377.1 - 7.5e-31 107.1 23.2 7.5e-31 107.1 16.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG14377.1 - 1.3e-07 30.5 8.4 1.3e-07 30.5 5.9 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter GPI-anchored PF10342.4 EKG14378.1 - 3.5e-22 78.6 2.0 4.5e-22 78.3 1.4 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2181 PF10223.4 EKG14378.1 - 0.007 15.7 0.0 0.0083 15.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) Prenyltrans_1 PF13243.1 EKG14378.1 - 0.037 14.0 0.8 0.093 12.7 0.1 2.0 2 1 0 2 2 2 0 Prenyltransferase-like SusE PF14292.1 EKG14378.1 - 0.039 13.7 0.7 0.07 12.9 0.3 1.6 1 1 1 2 2 2 0 SusE outer membrane protein Big_3_4 PF13754.1 EKG14378.1 - 0.27 11.5 0.3 0.27 11.5 0.2 2.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NmrA PF05368.8 EKG14379.1 - 1.1e-27 96.8 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG14379.1 - 9.2e-06 25.7 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Baculo_PEP_C PF04513.7 EKG14380.1 - 0.089 12.6 0.8 0.37 10.6 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EKG14380.1 - 0.27 9.8 7.6 0.49 8.9 5.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EKG14380.1 - 7.6 6.0 8.0 2.4 7.7 0.4 2.2 1 1 1 2 2 2 0 IncA protein MFS_1 PF07690.11 EKG14382.1 - 3.1e-26 91.9 28.8 3.5e-26 91.7 19.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG14382.1 - 2.1e-10 39.7 10.6 2.1e-10 39.7 7.4 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter PsbN PF02468.10 EKG14382.1 - 0.23 11.0 0.1 0.23 11.0 0.1 3.5 4 0 0 4 4 4 0 Photosystem II reaction centre N protein (psbN) Ank_2 PF12796.2 EKG14387.1 - 5.8e-50 167.5 14.0 7.5e-17 61.4 0.5 7.4 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG14387.1 - 3.2e-34 116.7 11.9 4.7e-07 30.1 0.1 10.7 7 3 5 12 12 11 5 Ankyrin repeats (many copies) Ank PF00023.25 EKG14387.1 - 5.8e-33 111.0 21.3 2.7e-07 30.0 0.0 11.1 11 0 0 11 11 10 5 Ankyrin repeat Ank_5 PF13857.1 EKG14387.1 - 2.5e-29 100.6 10.4 5.5e-05 23.2 0.0 9.4 9 1 0 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG14387.1 - 9.3e-29 96.6 17.4 4.1e-05 23.4 0.0 12.0 13 0 0 13 13 12 5 Ankyrin repeat SPRY PF00622.23 EKG14387.1 - 7.1e-16 58.4 0.4 1.3e-15 57.5 0.3 1.5 1 0 0 1 1 1 1 SPRY domain AAA_16 PF13191.1 EKG14387.1 - 6.4e-10 39.3 0.1 1.9e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EKG14387.1 - 1.7e-07 31.0 0.0 3.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EKG14387.1 - 4.4e-05 22.6 0.8 0.072 12.0 0.0 3.0 2 1 1 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.1 EKG14387.1 - 0.0001 22.4 0.0 0.00045 20.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain DUF349 PF03993.7 EKG14387.1 - 0.0074 16.4 0.5 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF349) ABC_tran PF00005.22 EKG14387.1 - 0.018 15.3 0.0 0.089 13.0 0.0 2.2 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 EKG14387.1 - 0.047 12.4 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 EKG14387.1 - 0.058 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain HisKA_3 PF07730.8 EKG14387.1 - 0.072 13.4 2.0 0.17 12.2 0.1 2.6 2 0 0 2 2 2 0 Histidine kinase Arch_ATPase PF01637.13 EKG14387.1 - 0.074 12.7 0.0 0.31 10.7 0.0 2.0 1 0 0 1 1 1 0 Archaeal ATPase ATG_C PF09333.6 EKG14389.1 - 4e-05 23.6 0.0 0.00014 21.9 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain DAO PF01266.19 EKG14390.1 - 5.5e-23 81.4 4.0 7.1e-23 81.0 2.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG14390.1 - 8.8e-06 25.6 0.5 3e-05 23.9 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG14390.1 - 1.1e-05 25.6 0.4 3.4e-05 24.1 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EKG14390.1 - 0.0016 18.6 0.0 0.0036 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EKG14390.1 - 0.014 14.4 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EKG14390.1 - 0.014 14.8 1.0 0.12 11.8 0.5 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EKG14390.1 - 0.02 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG14390.1 - 0.03 13.1 0.1 0.07 11.9 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EKG14390.1 - 0.042 13.5 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EKG14390.1 - 0.052 12.9 0.1 0.086 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PA-IL PF07828.7 EKG14390.1 - 0.055 13.2 0.0 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 PA-IL-like protein GIDA PF01134.17 EKG14390.1 - 0.065 12.0 0.2 0.095 11.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Nitroreductase PF00881.19 EKG14392.1 - 0.19 11.5 2.6 0.15 11.8 0.7 1.6 2 0 0 2 2 2 0 Nitroreductase family DUF4588 PF15251.1 EKG14392.1 - 5.3 6.9 17.4 1.5e+02 2.2 12.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) G_glu_transpept PF01019.16 EKG14393.1 - 7.7e-147 489.8 0.0 8.9e-147 489.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RF-1 PF00472.15 EKG14394.1 - 4e-33 113.6 1.1 7.8e-33 112.6 0.8 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EKG14394.1 - 5.8e-20 71.1 0.0 1.5e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 PCRF domain UTP15_C PF09384.5 EKG14396.1 - 1.2e-48 164.5 0.3 2.8e-47 160.1 0.0 2.5 2 1 1 3 3 3 1 UTP15 C terminal WD40 PF00400.27 EKG14396.1 - 5.3e-22 76.8 0.0 8.6e-07 28.6 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_L22 PF00237.14 EKG14397.1 - 4.9e-19 68.2 0.6 1.3e-09 37.9 0.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e DUF4283 PF14111.1 EKG14397.1 - 0.084 11.9 0.1 0.57 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4283) RRM_1 PF00076.17 EKG14398.1 - 2.8e-48 161.4 0.0 9.5e-14 50.7 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG14398.1 - 5.1e-45 151.3 0.2 5.7e-12 45.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG14398.1 - 5.1e-24 83.8 0.0 3.7e-05 23.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKG14398.1 - 7.7e-08 31.9 0.0 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EKG14398.1 - 0.037 13.4 2.3 0.038 13.4 0.2 2.2 2 0 0 2 2 2 0 Lsm interaction motif p450 PF00067.17 EKG14399.1 - 1.8e-39 135.5 0.0 2.5e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Clat_adaptor_s PF01217.15 EKG14400.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain TAF8_C PF10406.4 EKG14401.1 - 2.3e-21 75.5 0.5 5.8e-21 74.2 0.3 1.7 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EKG14401.1 - 7.4e-10 38.4 0.0 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated ADH_zinc_N_2 PF13602.1 EKG14403.1 - 5e-24 85.6 0.1 1.2e-23 84.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EKG14403.1 - 5.7e-18 64.7 0.3 1.2e-17 63.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase E1-N PF14463.1 EKG14403.1 - 0.055 13.0 0.3 0.15 11.6 0.2 1.7 1 0 0 1 1 1 0 E1 N-terminal domain Fungal_trans PF04082.13 EKG14404.1 - 3e-12 45.9 0.0 3.2e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 EKG14405.1 - 2.4e-10 39.7 0.0 4.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DUF4437 PF14499.1 EKG14405.1 - 0.0023 16.8 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4437) Cupin_1 PF00190.17 EKG14405.1 - 0.052 12.9 0.0 0.089 12.2 0.0 1.5 1 1 0 1 1 1 0 Cupin CDO_I PF05995.7 EKG14405.1 - 0.078 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I Dehydratase_hem PF13816.1 EKG14406.1 - 3.5e-99 331.7 0.0 4.7e-99 331.3 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EKG14406.1 - 5.2e-09 36.2 0.2 0.0046 17.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) TENA_THI-4 PF03070.11 EKG14406.1 - 5.4e-05 23.0 0.1 8.9e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family ABM PF03992.11 EKG14406.1 - 0.0037 17.2 1.9 0.21 11.6 0.5 2.5 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase RRM_6 PF14259.1 EKG14406.1 - 0.025 14.5 0.1 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.2 EKG14407.1 - 5.1e-77 254.2 0.4 1.2e-17 63.9 0.4 6.9 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EKG14407.1 - 9e-67 217.7 17.0 3e-06 26.7 0.1 14.2 15 0 0 15 15 14 12 Ankyrin repeat Ank_3 PF13606.1 EKG14407.1 - 5e-52 168.6 8.3 0.00015 21.6 0.0 13.7 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 EKG14407.1 - 6e-51 169.9 4.4 7.7e-07 29.4 0.0 9.2 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG14407.1 - 5.7e-47 156.6 17.0 1.1e-09 38.1 0.2 13.2 3 2 10 13 13 13 11 Ankyrin repeats (many copies) AAA_22 PF13401.1 EKG14407.1 - 2.3e-07 30.9 0.0 7.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG14407.1 - 8.2e-07 29.1 0.1 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ZZ PF00569.12 EKG14407.1 - 4.9e-06 25.9 6.0 9.6e-06 25.0 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type NACHT PF05729.7 EKG14407.1 - 6.3e-06 25.9 0.0 1.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain HeLo PF14479.1 EKG14407.1 - 6.6e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation AAA_19 PF13245.1 EKG14407.1 - 8.3e-05 22.2 0.1 0.00026 20.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EKG14407.1 - 0.00064 19.9 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EKG14407.1 - 0.052 13.1 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EKG14407.1 - 0.073 12.6 0.1 0.35 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EKG14407.1 - 0.078 11.8 0.0 0.19 10.5 0.0 1.5 1 1 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EKG14407.1 - 0.095 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 EKG14407.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 EKG14407.1 - 0.28 11.1 0.0 0.68 9.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_hydro_32N PF00251.15 EKG14409.1 - 5.1e-38 131.1 0.0 8.8e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EKG14409.1 - 2.2e-05 24.7 0.0 6.1e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EKG14409.1 - 0.029 14.1 4.2 0.098 12.5 0.4 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat BNR_2 PF13088.1 EKG14409.1 - 0.036 13.3 0.1 0.092 12.0 0.0 1.8 1 1 0 1 1 1 0 BNR repeat-like domain Fungal_trans PF04082.13 EKG14410.1 - 1.1e-06 27.7 0.3 1.5e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF791 PF05631.9 EKG14410.1 - 0.11 11.1 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF791) MFS_1 PF07690.11 EKG14411.1 - 1.8e-10 40.0 6.9 1.8e-10 40.0 4.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LacY_symp PF01306.14 EKG14411.1 - 0.097 11.2 7.9 0.13 10.7 5.4 1.3 1 1 0 1 1 1 0 LacY proton/sugar symporter DUF1043 PF06295.7 EKG14411.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF1556 PF07590.6 EKG14413.1 - 2.8 8.2 10.2 0.41 10.8 3.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1556) Glucan_synthase PF02364.10 EKG14414.1 - 0 1406.7 0.0 0 1406.2 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EKG14414.1 - 5.9e-40 135.8 0.1 1.6e-39 134.4 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF1034 PF06280.7 EKG14415.1 - 9e-09 35.7 0.1 1.4e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DUF4352 PF11611.3 EKG14415.1 - 0.0041 17.2 0.5 0.02 15.0 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4352) AA_permease_2 PF13520.1 EKG14416.1 - 4.6e-47 160.5 50.0 5.7e-47 160.2 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG14416.1 - 1.9e-32 112.2 45.5 2.4e-32 111.9 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 EKG14416.1 - 0.045 13.4 0.3 0.08 12.6 0.2 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Glyco_hydro_28 PF00295.12 EKG14418.1 - 8.6e-59 199.1 10.3 1.3e-58 198.4 7.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.8 EKG14418.1 - 0.00021 20.5 11.7 0.00036 19.7 8.1 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Hemerythrin PF01814.18 EKG14419.1 - 1.3e-09 38.2 4.0 1.7e-09 37.9 2.8 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain IL6 PF00489.12 EKG14419.1 - 0.076 12.5 0.0 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family DASH_Dad3 PF08656.5 EKG14419.1 - 0.096 12.3 0.9 4.9 6.9 0.6 2.2 1 1 0 1 1 1 0 DASH complex subunit Dad3 HMGL-like PF00682.14 EKG14420.1 - 2e-54 184.7 0.0 3.7e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EKG14420.1 - 1.6e-21 76.4 0.0 2.7e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain tRNA-synt_2c PF01411.14 EKG14421.1 - 2.7e-09 35.8 0.1 3.4e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EKG14421.1 - 4.9e-06 26.3 0.3 1.1e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF3445 PF11927.3 EKG14422.1 - 4e-65 219.6 0.0 4.8e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MFS_1 PF07690.11 EKG14425.1 - 0.00046 19.0 5.1 0.00058 18.6 3.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CLN3 PF02487.12 EKG14425.1 - 0.0029 16.4 0.4 0.0031 16.3 0.2 1.0 1 0 0 1 1 1 1 CLN3 protein DUF1049 PF06305.6 EKG14425.1 - 0.18 11.2 0.0 0.18 11.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) CD20 PF04103.10 EKG14425.1 - 4.5 7.1 7.3 0.28 11.1 1.6 1.5 2 0 0 2 2 2 0 CD20-like family DUF308 PF03729.8 EKG14425.1 - 5.7 7.0 16.6 0.71 9.8 2.5 2.4 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) FixP_N PF14715.1 EKG14425.1 - 8.2 5.9 9.3 2.5 7.5 1.7 2.4 1 1 1 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP HMGL-like PF00682.14 EKG14426.1 - 2.5e-11 43.6 0.0 3.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Methyltransf_23 PF13489.1 EKG14428.1 - 5e-14 52.3 0.0 7.2e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG14428.1 - 2.1e-13 50.5 0.0 4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG14428.1 - 2.8e-12 47.1 0.0 5.9e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG14428.1 - 1e-11 44.6 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG14428.1 - 2.6e-11 43.8 0.0 4.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG14428.1 - 6e-11 42.0 0.0 8.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EKG14428.1 - 2.7e-08 34.0 0.0 5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EKG14428.1 - 9.6e-06 24.8 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EKG14428.1 - 1.1e-05 24.6 0.0 2.3e-05 23.6 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EKG14428.1 - 2.2e-05 24.4 0.1 7.5e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EKG14428.1 - 4.1e-05 22.8 0.0 5.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EKG14428.1 - 8.9e-05 22.1 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKG14428.1 - 0.00022 20.8 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 EKG14428.1 - 0.00037 19.9 0.0 0.00058 19.3 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.6 EKG14428.1 - 0.0014 17.3 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.7 EKG14428.1 - 0.0017 17.2 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 EKG14428.1 - 0.015 14.4 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Spermine_synth PF01564.12 EKG14428.1 - 0.058 12.3 0.0 0.19 10.6 0.0 1.8 1 1 0 1 1 1 0 Spermine/spermidine synthase FmrO PF07091.6 EKG14428.1 - 0.066 12.1 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) SnoaL PF07366.7 EKG14428.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase Nol1_Nop2_Fmu PF01189.12 EKG14428.1 - 0.17 11.1 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 NOL1/NOP2/sun family DOT1 PF08123.8 EKG14428.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 MFS_1 PF07690.11 EKG14429.1 - 6.8e-38 130.2 36.6 6.8e-38 130.2 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG14429.1 - 4.1e-13 48.7 16.8 1.4e-12 46.9 11.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Bestrophin PF01062.16 EKG14429.1 - 0.031 13.2 0.5 0.064 12.1 0.4 1.5 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel MFS_1 PF07690.11 EKG14430.1 - 0.053 12.2 0.6 0.057 12.1 0.4 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Ldh_2 PF02615.9 EKG14431.1 - 4.5e-83 278.7 0.0 5.2e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Methyltransf_6 PF03737.10 EKG14432.1 - 9.9e-08 31.9 0.8 0.00033 20.5 0.3 2.1 1 1 1 2 2 2 2 Demethylmenaquinone methyltransferase F_bP_aldolase PF01116.15 EKG14433.1 - 5.8e-53 179.8 0.0 6.4e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SnoaL_4 PF13577.1 EKG14434.1 - 4.3e-06 26.6 0.1 6.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EKG14434.1 - 0.087 12.8 0.3 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 SnoaL-like domain SLAC1 PF03595.12 EKG14435.1 - 1.2e-80 270.6 46.5 1.4e-80 270.4 32.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Recep_L_domain PF01030.19 EKG14436.1 - 2e-06 27.7 0.1 1.6 8.7 0.0 4.0 2 1 2 4 4 4 3 Receptor L domain Ecm33 PF12454.3 EKG14436.1 - 0.017 14.9 0.2 0.097 12.5 0.1 2.2 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Myco_19_kDa PF05481.7 EKG14436.1 - 0.048 13.4 6.4 0.063 13.0 0.3 2.2 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen MBT PF02820.13 EKG14437.1 - 0.028 14.3 1.2 36 4.3 0.0 3.9 4 0 0 4 4 4 0 mbt repeat DUF2484 PF10658.4 EKG14440.1 - 0.06 13.4 3.1 0.084 13.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) DUF4405 PF14358.1 EKG14440.1 - 0.45 10.6 7.2 0.69 10.0 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) ADH_N PF08240.7 EKG14441.1 - 9e-17 60.8 0.1 4.1e-16 58.7 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG14441.1 - 2.4e-07 30.3 0.2 3.8e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EKG14441.1 - 0.033 12.6 0.0 0.05 12.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein adh_short PF00106.20 EKG14442.1 - 2.2e-31 109.0 0.1 3.2e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG14442.1 - 7.2e-31 107.7 0.3 8.8e-31 107.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG14442.1 - 3.7e-11 43.0 0.2 5.5e-11 42.4 0.1 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EKG14442.1 - 0.021 13.9 1.1 0.046 12.7 0.1 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EKG14442.1 - 0.028 13.8 0.1 0.096 12.1 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EKG14442.1 - 0.034 14.0 0.6 0.086 12.6 0.3 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 EKG14442.1 - 0.036 14.0 0.7 0.072 13.0 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKG14442.1 - 0.078 12.7 0.9 0.18 11.6 0.6 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Gln-synt_C PF00120.19 EKG14445.1 - 6.8e-60 202.3 0.0 8.3e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EKG14445.1 - 3.3e-20 71.4 0.0 7.6e-20 70.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Tbf5 PF06331.7 EKG14446.1 - 6.4e-21 73.9 0.6 7.2e-21 73.7 0.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 BRCA-2_OB3 PF09104.5 EKG14446.1 - 0.099 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF1325 PF07039.6 EKG14446.1 - 0.13 11.8 0.1 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain GFA PF04828.9 EKG14447.1 - 4.4e-24 84.2 0.0 5.9e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme WD40 PF00400.27 EKG14448.1 - 2e-61 201.8 24.3 1.6e-11 43.6 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EKG14448.1 - 0.00016 19.9 4.9 0.29 9.1 1.3 4.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EKG14448.1 - 0.078 11.2 0.1 4.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain ECH PF00378.15 EKG14449.1 - 8.5e-35 120.0 0.1 4.4e-23 81.6 0.2 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Iron_transport PF10634.4 EKG14449.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Fe2+ transport protein SR-25 PF10500.4 EKG14449.1 - 1.3 8.4 4.4 2.2 7.7 3.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med1 PF10744.4 EKG14450.1 - 3.6e-42 144.5 0.0 7.3e-42 143.5 0.0 1.5 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 NmrA PF05368.8 EKG14452.1 - 5.4e-30 104.3 0.0 6.9e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG14452.1 - 7.8e-09 35.7 0.5 1.9e-08 34.5 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EKG14452.1 - 0.00011 22.4 0.1 0.00021 21.5 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EKG14452.1 - 0.00077 18.5 0.5 0.0013 17.8 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EKG14452.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 EKG14452.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_trans_1_4 PF13692.1 EKG14452.1 - 0.091 12.9 0.1 0.73 9.9 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 CH PF00307.26 EKG14453.1 - 1.9e-10 40.7 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain NDUFA12 PF05071.11 EKG14454.1 - 1.9e-09 37.9 0.8 3.7e-09 36.9 0.1 2.0 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4558 PF15104.1 EKG14454.1 - 0.034 14.0 0.1 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4558) TPR_12 PF13424.1 EKG14455.1 - 1.3e-10 41.0 11.3 0.0055 16.6 0.5 3.9 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG14455.1 - 5.6e-05 22.6 9.8 0.0017 17.9 0.2 3.6 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 EKG14455.1 - 9.2e-05 21.9 5.5 0.14 12.0 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EKG14455.1 - 0.00041 20.0 11.8 1.7 8.7 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG14455.1 - 0.0038 17.7 13.1 3.4 8.5 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EKG14455.1 - 0.032 13.8 7.6 4.5 7.0 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKG14455.1 - 0.036 14.7 12.6 3.2 8.5 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.1 EKG14455.1 - 0.16 11.1 0.1 0.16 11.1 0.0 2.3 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_4 PF07721.9 EKG14455.1 - 0.36 11.4 0.2 0.36 11.4 0.2 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKG14455.1 - 1.2 9.0 4.0 16 5.5 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG14455.1 - 5.3 7.7 8.6 3 8.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF159 PF02586.9 EKG14456.1 - 1.6e-42 145.3 0.0 2.8e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Macoilin PF09726.4 EKG14456.1 - 0.38 8.9 10.3 0.48 8.6 7.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Isochorismatase PF00857.15 EKG14457.1 - 5.7e-28 98.0 0.1 7.5e-20 71.5 0.1 2.4 2 0 0 2 2 2 2 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 EKG14457.1 - 1.4e-23 83.7 0.1 2.6e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_2 PF13410.1 EKG14457.1 - 0.00053 19.8 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG14457.1 - 0.012 16.0 0.0 0.039 14.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ndc1_Nup PF09531.5 EKG14457.1 - 4.2 5.6 6.1 7.1 4.9 4.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-U1 PF06220.7 EKG14458.1 - 2.3e-06 27.0 0.9 3.1e-06 26.6 0.6 1.2 1 0 0 1 1 1 1 U1 zinc finger ORMDL PF04061.9 EKG14462.1 - 1.8e-60 202.3 4.3 2.1e-60 202.1 3.0 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EKG14462.1 - 0.11 12.1 2.6 0.078 12.6 0.5 1.6 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Ino80_Iec3 PF14612.1 EKG14463.1 - 3.4e-64 217.0 6.8 9.3e-64 215.6 4.7 1.6 1 1 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling GvpG PF05120.7 EKG14463.1 - 0.038 13.8 0.1 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle protein G HTH_28 PF13518.1 EKG14463.1 - 0.12 12.4 1.3 19 5.3 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain CorA PF01544.13 EKG14464.1 - 1.5e-15 57.0 2.9 3.4e-14 52.5 0.2 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DLH PF01738.13 EKG14465.1 - 7.8e-14 51.4 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG14465.1 - 5e-06 26.3 0.0 7.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG14465.1 - 5.9e-05 23.0 1.8 0.0065 16.3 0.3 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family FAD_binding_6 PF00970.19 EKG14467.1 - 2.9e-15 56.1 0.0 4.1e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EKG14467.1 - 9.2e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.6 EKG14467.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 EKG14467.1 - 0.055 13.3 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF2376 PF09550.5 EKG14467.1 - 0.069 13.3 0.3 5.2 7.3 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical phage protein (DUF2376) DUF4349 PF14257.1 EKG14468.1 - 0.0011 18.3 1.6 0.0011 18.3 1.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4349) V_ATPase_I PF01496.14 EKG14468.1 - 0.41 8.4 2.6 0.47 8.2 1.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TATR PF03430.8 EKG14468.1 - 3.6 6.1 13.5 4.3 5.8 9.3 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Retrotrans_gag PF03732.12 EKG14469.1 - 1.8e-09 37.5 0.8 1.8e-09 37.5 0.6 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF972 PF06156.8 EKG14469.1 - 0.0015 18.8 0.2 0.017 15.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF972) DivIC PF04977.10 EKG14469.1 - 0.028 13.9 0.6 0.069 12.6 0.4 1.6 1 0 0 1 1 1 0 Septum formation initiator PspA_IM30 PF04012.7 EKG14469.1 - 0.11 11.8 0.2 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 PspA/IM30 family Nnf1 PF03980.9 EKG14469.1 - 0.14 12.1 0.9 0.34 10.9 0.2 1.9 2 0 0 2 2 2 0 Nnf1 IL6 PF00489.12 EKG14469.1 - 0.16 11.5 1.0 0.45 10.0 0.1 2.0 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family bZIP_2 PF07716.10 EKG14469.1 - 0.33 10.8 2.0 0.67 9.8 1.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EKG14469.1 - 0.65 9.5 3.8 0.78 9.2 0.8 1.9 2 0 0 2 2 2 0 IncA protein RVP_2 PF08284.6 EKG14470.1 - 3.5e-08 33.4 0.0 5.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EKG14470.1 - 6.8e-05 23.2 0.0 0.00023 21.6 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EKG14470.1 - 0.00038 20.2 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease adh_short PF00106.20 EKG14473.1 - 3.4e-24 85.6 0.2 1e-23 84.0 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG14473.1 - 5.6e-08 32.8 0.0 8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG14473.1 - 1.3e-06 28.1 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG14473.1 - 1.5e-06 28.3 0.5 2.7e-06 27.5 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG14473.1 - 4.7e-05 22.9 0.2 0.00014 21.4 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EKG14473.1 - 6.4e-05 23.0 0.0 9.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EKG14473.1 - 0.00053 20.3 0.1 0.001 19.4 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EKG14473.1 - 0.00076 19.2 0.3 0.0014 18.3 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EKG14473.1 - 0.0064 15.6 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 EKG14473.1 - 0.0092 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EKG14473.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EKG14473.1 - 0.024 14.3 0.1 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EKG14473.1 - 0.031 13.6 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EKG14473.1 - 0.042 12.8 0.4 0.058 12.3 0.3 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EKG14473.1 - 0.051 12.4 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EKG14473.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EKG14474.1 - 0.00047 20.1 0.1 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF4345 PF14248.1 EKG14474.1 - 0.068 12.6 0.2 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) TauE PF01925.14 EKG14474.1 - 0.1 12.0 0.2 0.14 11.5 0.2 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE zf-PHD-like PF15446.1 EKG14475.1 - 2.1e-67 225.7 11.5 4e-67 224.8 8.0 1.4 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EKG14475.1 - 5.1e-60 202.8 0.0 7.1e-60 202.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG14475.1 - 1.5e-12 47.2 0.0 4.3e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EKG14475.1 - 5.3e-10 38.5 0.2 1.1e-09 37.5 0.2 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EKG14475.1 - 0.00039 20.3 0.0 0.0022 17.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Chromo PF00385.19 EKG14475.1 - 0.00041 19.9 1.7 0.022 14.4 0.0 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EKG14475.1 - 0.00071 19.2 18.2 0.00073 19.1 0.9 3.9 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 EKG14475.1 - 0.95 8.8 19.4 0.014 14.6 4.3 3.9 3 1 1 4 4 4 0 PHD-finger Prok-RING_1 PF14446.1 EKG14475.1 - 3.2 7.5 12.6 0.59 9.9 1.7 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 SpoU_methylase PF00588.14 EKG14476.1 - 4.3e-24 84.9 0.0 2.1e-23 82.7 0.0 2.0 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EKG14476.1 - 0.057 13.5 0.0 0.65 10.2 0.0 2.7 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Seryl_tRNA_N PF02403.17 EKG14476.1 - 0.088 12.8 3.4 8.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PLDc_2 PF13091.1 EKG14477.1 - 2.8e-19 69.1 0.0 1.6e-13 50.5 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EKG14477.1 - 0.056 13.2 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Phospholipase D Active site motif ECR1_N PF14382.1 EKG14478.1 - 1.5e-11 43.3 0.1 3.8e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EKG14478.1 - 0.005 16.7 0.1 0.071 13.0 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Chitin_synth_2 PF03142.10 EKG14478.1 - 0.033 12.5 0.0 0.045 12.1 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase AMP-binding PF00501.23 EKG14479.1 - 1.9e-14 52.8 0.9 3e-13 48.9 0.2 2.7 2 1 0 2 2 2 2 AMP-binding enzyme Cm_res_leader PF08077.6 EKG14479.1 - 0.1 12.3 3.7 3 7.7 0.1 2.7 2 0 0 2 2 2 0 Chloramphenicol resistance gene leader peptide HET PF06985.6 EKG14480.1 - 8.7e-15 55.0 0.0 2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF639 PF04842.7 EKG14481.1 - 0.044 11.9 0.0 0.05 11.7 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) MFS_1 PF07690.11 EKG14482.1 - 3.4e-26 91.7 27.7 9.3e-26 90.3 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EKG14483.1 - 1.4e-20 73.6 0.0 2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG14483.1 - 1.8e-09 36.9 0.3 2.7e-05 23.2 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG14483.1 - 0.00012 21.9 0.1 0.00041 20.3 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG14483.1 - 0.00061 20.1 0.3 0.0095 16.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG14483.1 - 0.019 13.8 0.2 0.037 12.8 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EKG14483.1 - 0.033 14.2 0.1 0.11 12.5 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG14483.1 - 0.043 12.7 0.1 0.09 11.6 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein SE PF08491.5 EKG14483.1 - 0.079 11.7 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.9 EKG14483.1 - 0.095 12.5 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EKG14483.1 - 0.097 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAP_C PF07932.7 EKG14484.1 - 2.1e-36 123.9 0.0 4.5e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 D-aminopeptidase, domain C Beta-lactamase PF00144.19 EKG14484.1 - 2.4e-33 115.5 3.6 4.1e-33 114.7 2.5 1.4 1 0 0 1 1 1 1 Beta-lactamase DAP_B PF07930.7 EKG14484.1 - 6.3e-05 22.6 0.1 0.00022 20.8 0.0 1.9 2 0 0 2 2 2 1 D-aminopeptidase, domain B PAS_9 PF13426.1 EKG14485.1 - 0.043 14.1 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 PAS domain PAS_4 PF08448.5 EKG14485.1 - 0.051 13.6 0.1 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 PAS fold HATPase_c PF02518.21 EKG14486.1 - 1e-26 92.7 0.0 1.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG14486.1 - 7.6e-24 83.8 0.1 1.1e-22 80.1 0.0 2.4 2 1 0 3 3 3 1 Response regulator receiver domain MFS_1 PF07690.11 EKG14487.1 - 4e-18 65.2 50.4 4.9e-18 64.9 33.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG14487.1 - 0.00021 19.6 21.3 0.0006 18.1 14.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DIOX_N PF14226.1 EKG14488.1 - 2.1e-27 95.9 0.0 3.3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG14488.1 - 8.7e-21 74.0 0.0 2.8e-20 72.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PEX-2N PF09263.5 EKG14488.1 - 0.055 13.7 0.1 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Transp_cyt_pur PF02133.10 EKG14489.1 - 1.7e-36 125.7 5.0 2e-36 125.4 3.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TFIIA PF03153.8 EKG14490.1 - 8.9 6.0 5.8 13 5.5 4.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_25 PF01755.12 EKG14494.1 - 5.7e-05 22.8 0.0 0.025 14.2 0.0 3.0 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Fungal_trans_2 PF11951.3 EKG14495.1 - 0.0012 17.5 0.0 0.0013 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain KdgM PF06178.8 EKG14495.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) H_PPase PF03030.11 EKG14495.1 - 0.17 10.1 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase PhyH PF05721.8 EKG14496.1 - 2.4e-55 187.8 0.0 3.1e-55 187.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease PF00324.16 EKG14497.1 - 2.9e-105 352.3 36.5 3.4e-105 352.1 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG14497.1 - 1.8e-28 99.2 40.5 2.2e-28 99.0 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EKG14497.1 - 0.042 13.5 0.6 0.042 13.5 0.4 3.9 4 2 0 4 4 4 0 Domain of unknown function (DUF1772) NAD_binding_4 PF07993.7 EKG14498.1 - 6.2e-38 130.1 0.0 8.9e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EKG14498.1 - 1.5e-16 59.8 0.0 1.8e-15 56.2 0.0 2.5 3 0 0 3 3 3 1 AMP-binding enzyme Epimerase PF01370.16 EKG14498.1 - 1.5e-10 40.9 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EKG14498.1 - 7.9e-09 35.6 0.1 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EKG14498.1 - 1.8e-05 24.7 0.1 5.4e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EKG14498.1 - 0.0018 17.0 0.0 0.0029 16.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SlyX PF04102.7 EKG14499.1 - 0.0078 16.5 4.1 0.045 14.1 0.2 3.8 3 0 0 3 3 3 1 SlyX Ank_4 PF13637.1 EKG14499.1 - 0.013 16.0 0.1 0.047 14.2 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) LOH1CR12 PF10158.4 EKG14499.1 - 0.015 15.1 2.2 0.015 15.1 1.5 4.0 2 2 2 4 4 4 0 Tumour suppressor protein Med9 PF07544.8 EKG14499.1 - 0.36 10.6 8.5 0.39 10.4 0.7 3.4 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 EKG14499.1 - 2.3 8.0 12.7 32 4.3 0.0 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.1 EKG14499.1 - 7.2 6.5 9.3 0.92 9.4 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) 2-Hacid_dh_C PF02826.14 EKG14501.1 - 7.9e-42 142.4 0.0 1.1e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG14501.1 - 2.1e-09 36.9 0.0 3.4e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Oxidored_nitro PF00148.14 EKG14501.1 - 0.0086 14.7 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase Cu-oxidase PF00394.17 EKG14502.1 - 4.2e-08 33.2 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase CN_hydrolase PF00795.17 EKG14506.1 - 3.1e-32 111.4 0.0 4.2e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase IDO PF01231.13 EKG14508.1 - 0.0015 17.0 0.0 0.002 16.6 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Amidohydro_1 PF01979.15 EKG14509.1 - 1.1e-53 183.1 0.1 1.3e-53 182.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EKG14509.1 - 8.4e-15 54.8 0.5 3.4e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EKG14509.1 - 3.7e-14 53.4 0.4 1.9e-10 41.2 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EKG14509.1 - 8e-10 38.3 0.0 2.8e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 EKG14509.1 - 0.033 13.1 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Adenosine/AMP deaminase Claudin_2 PF13903.1 EKG14510.1 - 7.6e-05 22.4 2.5 0.0001 22.0 1.8 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 EKG14510.1 - 0.0019 18.2 5.2 0.0054 16.7 3.6 1.8 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Amastin PF07344.6 EKG14510.1 - 0.046 13.3 5.8 0.17 11.4 1.1 2.1 2 0 0 2 2 2 0 Amastin surface glycoprotein tRNA-synt_1b PF00579.20 EKG14512.1 - 4.6e-35 121.1 0.0 2.9e-34 118.5 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MFS_1 PF07690.11 EKG14513.1 - 3.5e-31 108.2 26.7 5.5e-31 107.5 18.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily BT1 PF03092.11 EKG14513.1 - 0.042 12.5 4.3 0.027 13.1 0.7 2.0 2 0 0 2 2 2 0 BT1 family DUF4149 PF13664.1 EKG14513.1 - 0.13 12.3 0.2 0.13 12.3 0.1 3.9 4 1 1 5 5 5 0 Domain of unknown function (DUF4149) DIOX_N PF14226.1 EKG14514.1 - 3.3e-06 27.6 0.0 5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal GATase PF00117.23 EKG14516.1 - 1.2e-09 37.9 0.0 1.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EKG14516.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 HET PF06985.6 EKG14518.1 - 1.1e-28 100.1 0.2 2.3e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 EKG14518.1 - 2.4e-19 69.8 4.8 4.7e-19 68.9 3.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG14518.1 - 2.2e-08 33.9 2.4 6.5e-08 32.4 1.7 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG14518.1 - 1.7e-07 31.2 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EKG14518.1 - 0.0022 18.1 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EKG14518.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF2036 PF09724.4 EKG14519.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) Fungal_trans_2 PF11951.3 EKG14520.1 - 0.013 14.1 0.3 0.023 13.2 0.2 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain HET PF06985.6 EKG14521.1 - 3.9e-33 114.5 0.6 6.2e-33 113.8 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) EF-hand_1 PF00036.27 EKG14522.1 - 6.8e-37 121.9 17.5 3.6e-09 35.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EKG14522.1 - 4.3e-34 116.4 8.0 3.2e-17 62.4 1.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EKG14522.1 - 1.9e-31 107.4 14.2 5e-13 48.4 0.6 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EKG14522.1 - 1.5e-28 96.0 11.9 4.5e-09 35.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EKG14522.1 - 1.1e-23 81.4 14.1 2.9e-06 26.3 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EKG14522.1 - 5.7e-16 58.1 0.1 3.4e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EKG14522.1 - 7.9e-09 35.1 5.0 0.00082 19.0 0.3 2.6 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EKG14522.1 - 2.3e-07 30.8 0.1 0.024 14.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EKG14522.1 - 0.00042 20.0 0.4 0.31 10.7 0.0 2.8 1 1 2 3 3 3 2 Tellurite resistance protein TerB Caleosin PF05042.8 EKG14522.1 - 0.00088 18.8 0.0 0.2 11.1 0.0 2.2 1 1 1 2 2 2 1 Caleosin related protein UPF0154 PF03672.8 EKG14522.1 - 0.0009 18.8 0.1 2.1 8.0 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_10 PF14788.1 EKG14522.1 - 0.0012 18.4 6.1 0.014 15.0 0.1 3.8 2 2 2 4 4 4 2 EF hand LNS2 PF08235.8 EKG14522.1 - 0.006 16.1 0.3 2.3 7.7 0.0 2.2 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) MgtE_N PF03448.12 EKG14522.1 - 0.006 16.8 1.3 2.6 8.4 0.1 2.2 1 1 1 2 2 2 2 MgtE intracellular N domain DUF2267 PF10025.4 EKG14522.1 - 0.013 15.5 0.0 0.25 11.3 0.0 2.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF1880 PF08976.6 EKG14522.1 - 0.042 13.9 0.2 7.1 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) YqeY PF09424.5 EKG14522.1 - 0.042 13.6 0.6 0.51 10.1 0.1 2.1 1 1 1 2 2 2 0 Yqey-like protein RloB PF13707.1 EKG14522.1 - 0.062 12.9 0.8 0.3 10.7 0.6 2.1 1 1 0 1 1 1 0 RloB-like protein Toprim_2 PF13155.1 EKG14522.1 - 0.077 13.3 0.9 1.3 9.3 0.2 2.2 1 1 1 2 2 2 0 Toprim-like DUF1456 PF07308.8 EKG14522.1 - 0.12 12.4 0.3 8.2 6.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) FAD_binding_4 PF01565.18 EKG14523.1 - 1.4e-19 69.8 0.1 2.7e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain CbtA PF09490.5 EKG14523.1 - 0.028 13.7 0.2 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Sec1 PF00995.18 EKG14528.1 - 3.5e-156 521.1 0.0 4.4e-156 520.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Btz PF09405.5 EKG14529.1 - 0.064 13.3 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding Oxysterol_BP PF01237.13 EKG14530.1 - 1e-111 372.8 0.0 2.3e-111 371.7 0.0 1.5 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EKG14530.1 - 2.5e-39 133.2 0.2 5e-39 132.2 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EKG14530.1 - 3.8e-07 30.2 0.9 8.7e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EKG14530.1 - 0.017 15.3 3.8 0.022 15.0 0.7 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain PIF1 PF05970.9 EKG14532.1 - 4.9e-56 190.2 0.0 2.3e-53 181.4 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EKG14532.1 - 3.7e-16 59.2 0.0 8.3e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG14532.1 - 3.4e-05 23.9 0.0 8.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG14532.1 - 0.00013 21.6 0.1 0.0004 20.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EKG14532.1 - 0.00024 21.2 0.0 0.00081 19.5 0.0 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.9 EKG14532.1 - 0.00035 18.4 0.0 0.00057 17.7 0.0 1.3 1 0 0 1 1 1 1 Helicase PhoH PF02562.11 EKG14532.1 - 0.0006 19.0 0.0 0.0028 16.9 0.0 2.1 3 0 0 3 3 3 1 PhoH-like protein IstB_IS21 PF01695.12 EKG14532.1 - 0.0011 18.4 0.2 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.1 EKG14532.1 - 0.0012 18.5 0.0 0.14 11.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG14532.1 - 0.0026 17.7 0.7 0.064 13.2 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.24 EKG14532.1 - 0.0045 17.1 0.0 0.016 15.4 0.0 1.9 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EKG14532.1 - 0.016 15.1 0.0 0.055 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EKG14532.1 - 0.027 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EKG14532.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EKG14532.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 EKG14532.1 - 0.079 12.6 0.3 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EKG14532.1 - 0.18 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sulfate_transp PF00916.15 EKG14534.1 - 8.5e-07 28.2 2.7 8.5e-07 28.2 1.9 3.0 1 1 0 3 3 3 2 Sulfate transporter family MFS_1 PF07690.11 EKG14535.1 - 2.7e-43 148.0 32.8 9.5e-40 136.3 15.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG14535.1 - 8.5e-07 27.8 14.5 8.5e-07 27.8 10.0 2.4 2 1 0 3 3 3 1 Sugar (and other) transporter GMC_oxred_N PF00732.14 EKG14536.1 - 5.7e-51 173.4 0.1 7.9e-51 172.9 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG14536.1 - 6e-36 123.8 0.0 1.1e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG14536.1 - 1.8e-07 30.3 0.5 0.00048 19.0 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EKG14536.1 - 2.7e-06 26.5 0.9 7.7e-05 21.7 0.1 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG14536.1 - 0.00039 20.3 0.3 0.0018 18.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG14536.1 - 0.00096 19.1 1.3 0.0027 17.6 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG14536.1 - 0.0036 17.3 0.1 1 9.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG14536.1 - 0.038 12.9 0.3 0.075 11.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EKG14536.1 - 0.039 12.4 0.4 0.15 10.5 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Xin PF08043.7 EKG14536.1 - 0.072 12.7 0.9 0.18 11.5 0.6 1.7 1 0 0 1 1 1 0 Xin repeat Thi4 PF01946.12 EKG14536.1 - 0.088 11.8 1.3 0.2 10.7 0.9 1.5 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 EKG14538.1 - 9.2e-18 64.2 0.2 2.7e-09 36.6 0.0 2.1 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EKG14538.1 - 1.2e-05 25.1 0.0 1.6e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EKG14538.1 - 0.00086 19.0 0.0 0.0011 18.6 0.0 1.3 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG14538.1 - 0.085 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EKG14538.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_deac_1 PF01522.16 EKG14539.1 - 2.1e-27 95.2 0.0 3.1e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EKG14539.1 - 4.3e-07 29.8 13.0 8.4e-07 28.8 9.0 1.4 1 0 0 1 1 1 1 Chitin recognition protein Glyco_tranf_2_3 PF13641.1 EKG14539.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.10 EKG14540.1 - 8e-41 140.0 1.0 2.8e-37 128.2 0.7 2.1 1 1 0 1 1 1 1 Chitin synthase PA_decarbox PF05870.6 EKG14540.1 - 2e-08 33.9 0.1 4.2e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Glyco_trans_2_3 PF13632.1 EKG14540.1 - 1.1e-07 31.7 12.7 2.1e-07 30.8 4.3 2.5 2 1 0 2 2 2 2 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EKG14540.1 - 1.1e-06 28.3 0.1 0.001 18.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EKG14540.1 - 4.1e-05 23.4 0.1 0.0066 16.2 0.1 2.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 ComFB PF10719.4 EKG14541.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Late competence development protein ComFB DUF962 PF06127.6 EKG14544.1 - 0.18 11.6 1.9 1.1 9.1 1.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF962) MFS_2 PF13347.1 EKG14545.1 - 7.6e-11 41.0 4.0 7.6e-11 41.0 2.8 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EKG14545.1 - 0.00074 19.2 0.0 0.0026 17.4 0.0 2.0 1 0 0 1 1 1 1 MFS_1 like family Lig_chan PF00060.21 EKG14545.1 - 0.96 9.1 8.4 1.1 8.9 2.8 2.6 2 1 1 3 3 3 0 Ligand-gated ion channel PEP-utilisers_N PF05524.8 EKG14546.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF2620 PF10941.3 EKG14546.1 - 0.032 14.2 0.1 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2620 Fez1 PF06818.10 EKG14546.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Fez1 CrtC PF07143.6 EKG14547.1 - 2.6e-14 53.2 1.4 3e-14 53.0 1.0 1.1 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) DUF1391 PF07151.7 EKG14547.1 - 1.8 8.0 6.3 1.9 8.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1391) Nramp PF01566.13 EKG14548.1 - 1.8e-34 119.1 12.8 2e-24 86.0 0.4 2.1 1 1 1 2 2 2 2 Natural resistance-associated macrophage protein FAD_binding_3 PF01494.14 EKG14551.1 - 5.4e-17 61.8 0.5 8.5e-17 61.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG14551.1 - 9.7e-10 37.8 7.7 1.9e-06 27.0 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG14551.1 - 1e-05 25.4 1.0 2.7e-05 24.0 0.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EKG14551.1 - 1.9e-05 23.9 1.8 3.8e-05 22.9 1.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG14551.1 - 2e-05 24.8 1.7 0.0053 17.1 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EKG14551.1 - 3.6e-05 23.0 4.4 0.0056 15.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EKG14551.1 - 0.00024 21.2 0.2 0.00056 20.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG14551.1 - 0.00064 19.6 1.1 0.0038 17.1 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG14551.1 - 0.0057 15.1 6.5 0.14 10.6 2.6 2.2 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 EKG14551.1 - 0.0059 15.5 0.5 0.009 14.9 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EKG14551.1 - 0.0094 14.8 9.5 0.014 14.2 4.8 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EKG14551.1 - 0.043 12.8 0.2 0.083 11.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EKG14551.1 - 0.1 11.3 0.0 0.21 10.3 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase Exonuc_VII_S PF02609.11 EKG14551.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit Adenylsucc_synt PF00709.16 EKG14552.1 - 3.8e-165 549.6 0.0 4.3e-165 549.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF416 PF04222.7 EKG14553.1 - 0.0097 15.0 1.6 0.018 14.2 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF416) HTH_Tnp_1 PF01527.15 EKG14553.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 Transposase Rhabdo_ncap PF00945.13 EKG14553.1 - 1.1 7.8 3.8 1.9 6.9 2.6 1.4 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2457 PF10446.4 EKG14553.1 - 1.9 7.1 24.3 2 7.0 13.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BTV_NS2 PF04514.7 EKG14553.1 - 2.6 6.8 7.1 5.3 5.8 4.9 1.6 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 EKG14553.1 - 5.3 4.9 14.0 9.9 4.0 9.7 1.5 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EKG14553.1 - 6.4 5.9 15.9 10 5.2 11.0 1.3 1 0 0 1 1 1 0 NOA36 protein CAF1A PF12253.3 EKG14553.1 - 6.5 6.9 19.5 15 5.7 13.5 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A MRC1 PF09444.5 EKG14554.1 - 2.1e-36 125.3 20.3 2.1e-36 125.3 14.1 7.3 6 1 1 7 7 7 1 MRC1-like domain DUF3439 PF11921.3 EKG14554.1 - 1.5 8.6 12.0 0.18 11.5 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) COQ7 PF03232.8 EKG14555.1 - 3.1e-52 176.5 0.4 3.4e-52 176.3 0.3 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 GlutR_dimer PF00745.15 EKG14555.1 - 0.07 13.0 0.6 0.12 12.2 0.3 1.4 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Plus-3 PF03126.13 EKG14556.1 - 1.1e-34 118.7 0.0 3e-34 117.3 0.0 1.8 2 0 0 2 2 2 1 Plus-3 domain Cu-oxidase_3 PF07732.10 EKG14557.1 - 4.6e-44 148.9 11.4 3.1e-43 146.2 0.6 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG14557.1 - 9.9e-36 122.2 7.3 4.3e-30 104.0 3.5 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG14557.1 - 7.8e-34 116.8 0.1 1.2e-32 112.9 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.11 EKG14558.1 - 3.7e-42 144.3 50.0 6.7e-42 143.4 34.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG14558.1 - 1.6e-06 27.0 15.3 1.6e-06 27.0 10.6 3.2 2 2 2 4 4 4 2 Sugar (and other) transporter Lipase_3 PF01764.20 EKG14560.1 - 1.4e-31 109.0 0.0 1.9e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EKG14560.1 - 0.00098 18.9 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EKG14560.1 - 0.0012 19.1 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EKG14560.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EKG14560.1 - 0.0017 17.7 0.0 0.0079 15.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EKG14560.1 - 0.0018 18.1 0.0 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EKG14560.1 - 0.011 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EKG14560.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 EKG14560.1 - 0.026 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF3463 PF11946.3 EKG14560.1 - 0.06 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) UPF0227 PF05728.7 EKG14560.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.15 EKG14560.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative esterase ArfGap PF01412.13 EKG14561.1 - 3.5e-36 123.5 0.1 3.5e-36 123.5 0.0 2.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EKG14561.1 - 5.5e-09 36.1 0.1 1.6e-08 34.6 0.0 1.9 1 0 0 1 1 1 1 PH domain PI3_PI4_kinase PF00454.22 EKG14564.1 - 9e-41 139.8 0.0 3.4e-40 137.9 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EKG14564.1 - 2.3e-25 88.8 0.1 5.2e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) zf-C3HC4_3 PF13920.1 EKG14565.1 - 0.00065 19.3 10.0 0.00065 19.3 6.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Tudor-knot PF11717.3 EKG14565.1 - 0.025 14.2 0.7 0.065 12.9 0.5 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Velvet PF11754.3 EKG14566.1 - 2.6e-72 242.6 0.0 3.2e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Velvet factor TSP_1 PF00090.14 EKG14567.1 - 0.092 12.8 2.0 0.18 11.9 1.4 1.4 1 0 0 1 1 1 0 Thrombospondin type 1 domain DAGAT PF03982.8 EKG14568.1 - 6.2e-92 307.4 0.0 8.3e-92 307.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Stk19 PF10494.4 EKG14569.1 - 2.5e-45 154.8 0.0 3.6e-23 82.2 0.0 2.1 1 1 1 2 2 2 2 Serine-threonine protein kinase 19 CFEM PF05730.6 EKG14570.1 - 2.7e-12 46.3 11.8 2.7e-12 46.3 8.2 2.4 2 1 0 2 2 2 1 CFEM domain PAP1 PF08601.5 EKG14570.1 - 0.15 11.7 3.9 0.19 11.3 2.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Sporozoite_P67 PF05642.6 EKG14570.1 - 1.3 6.7 11.1 1.5 6.5 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.3 EKG14570.1 - 3 7.0 14.7 4.1 6.5 10.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L38e PF01781.13 EKG14571.1 - 6.5e-35 118.7 1.5 7.7e-35 118.4 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Glyco_hydro_47 PF01532.15 EKG14572.1 - 6.3e-154 512.9 0.0 7.1e-154 512.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FMN_dh PF01070.13 EKG14573.1 - 4.2e-61 206.7 4.8 4.8e-61 206.5 3.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EKG14573.1 - 5.1e-08 32.1 0.4 1.1e-07 31.0 0.2 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EKG14573.1 - 3.1e-07 29.6 0.1 3.8e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EKG14573.1 - 4.6e-07 29.2 3.6 5.9e-07 28.9 2.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EKG14573.1 - 4e-06 26.2 0.1 8e-05 22.0 0.0 2.1 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EKG14573.1 - 0.00065 18.8 0.9 0.012 14.7 0.0 2.1 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EKG14573.1 - 0.005 15.8 0.0 0.02 13.8 0.0 1.9 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EKG14573.1 - 0.03 13.5 1.5 1.5 8.0 0.0 2.1 1 1 1 2 2 2 0 PcrB family Dus PF01207.12 EKG14573.1 - 0.041 12.7 0.1 0.075 11.8 0.0 1.3 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) GST_C_2 PF13410.1 EKG14574.1 - 4.2e-10 39.3 0.1 9.2e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG14574.1 - 6.5e-08 32.6 0.0 1.5e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG14574.1 - 1.4e-05 25.4 0.0 2.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG14574.1 - 5.5e-05 23.0 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EKG14574.1 - 6.3e-05 22.8 0.1 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_transf_90 PF05686.7 EKG14575.1 - 3.5e-28 98.4 2.2 4.6e-28 98.0 1.5 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 DUF3768 PF12599.3 EKG14575.1 - 0.053 13.4 0.1 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3768) Glyco_trans_1_2 PF13524.1 EKG14575.1 - 0.072 13.3 1.7 0.11 12.8 0.0 2.1 3 0 0 3 3 3 0 Glycosyl transferases group 1 DUF3951 PF13131.1 EKG14575.1 - 0.11 12.3 0.6 0.21 11.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) PALP PF00291.20 EKG14576.1 - 9.3e-29 100.6 1.5 1.1e-28 100.4 1.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HTH_Tnp_1 PF01527.15 EKG14576.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 Transposase PPTA PF01239.17 EKG14577.1 - 4.6e-44 145.9 11.2 2.7e-08 32.8 0.1 6.3 6 0 0 6 6 6 6 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 EKG14577.1 - 0.011 16.4 5.7 3.1 8.5 0.4 3.7 3 1 0 4 4 4 0 Tetratricopeptide repeat DUF4219 PF13961.1 EKG14577.1 - 1.6 8.2 9.7 7.1 6.1 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4219) TPR_8 PF13181.1 EKG14577.1 - 2.5 8.0 6.2 8.9 6.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKG14577.1 - 5.1 6.8 9.3 2.1 8.0 0.2 3.8 2 2 2 4 4 4 0 TPR repeat Med19 PF10278.4 EKG14578.1 - 0.011 15.4 5.9 0.017 14.7 4.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Zip PF02535.17 EKG14578.1 - 0.13 11.2 8.2 0.22 10.4 5.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EKG14578.1 - 1.2 8.5 16.3 2.3 7.5 11.3 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PBP_sp32 PF07222.7 EKG14578.1 - 2.1 7.4 6.6 3.9 6.5 4.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SR-25 PF10500.4 EKG14578.1 - 9.1 5.6 17.2 0.1 12.0 5.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein GDE_N_bis PF14742.1 EKG14579.1 - 0.038 13.3 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes ADH_N PF08240.7 EKG14580.1 - 5.7e-06 26.0 0.0 7.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NTF2 PF02136.15 EKG14582.1 - 1e-05 25.8 2.7 0.0013 19.0 1.9 2.3 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain FLILHELTA PF10306.4 EKG14582.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein FLILHELTA C2 PF00168.25 EKG14583.1 - 2.9e-08 33.4 0.0 5.8e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.11 EKG14584.1 - 2e-33 115.5 32.0 1.3e-32 112.9 23.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3671 PF12420.3 EKG14584.1 - 4 7.4 4.8 2.4 8.1 0.1 2.9 3 2 0 3 3 3 0 Protein of unknown function SRA1 PF07304.6 EKG14585.1 - 0.12 12.0 0.8 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Band_7 PF01145.20 EKG14588.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF4034 PF13226.1 EKG14588.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) Dus PF01207.12 EKG14589.1 - 1.2e-43 149.1 0.0 3.8e-43 147.4 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EKG14589.1 - 0.043 12.9 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI GMC_oxred_C PF05199.8 EKG14590.1 - 7.7e-25 87.8 0.0 1.1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Abhydrolase_1 PF00561.15 EKG14593.1 - 7.9e-16 58.3 0.0 4.4e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG14593.1 - 8.9e-14 51.9 0.2 1.4e-13 51.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG14593.1 - 0.0039 16.9 0.0 0.0094 15.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.4 EKG14593.1 - 0.0043 15.9 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) RRS1 PF04939.7 EKG14594.1 - 8.8e-59 197.6 4.8 1e-58 197.4 3.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 EKG14595.1 - 9.4e-94 313.8 0.0 1.1e-93 313.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EKG14595.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EKG14595.1 - 0.0049 16.7 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain MFS_1 PF07690.11 EKG14596.1 - 6.8e-06 25.0 29.0 0.00097 17.9 17.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OpuAC PF04069.7 EKG14596.1 - 0.04 13.2 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Fungal_trans PF04082.13 EKG14597.1 - 0.00028 19.8 0.0 0.00065 18.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG14597.1 - 0.00034 20.4 7.3 0.00068 19.4 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSCB_C PF07743.8 EKG14597.1 - 0.11 12.9 0.6 0.33 11.4 0.4 1.8 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Fe-ADH PF00465.14 EKG14598.1 - 6.8e-60 202.6 0.0 9.2e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKG14598.1 - 3.6e-06 26.4 0.3 1.4e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase MFS_1 PF07690.11 EKG14599.1 - 2.2e-36 125.3 24.9 2.2e-36 125.3 17.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily NAD_Gly3P_dh_C PF07479.9 EKG14601.1 - 2.4e-43 147.4 0.2 5.2e-43 146.3 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EKG14601.1 - 6.5e-38 129.9 0.0 1.3e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-LYAR PF08790.6 EKG14602.1 - 2.4e-15 55.9 4.6 2.4e-15 55.9 3.2 1.8 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Evr1_Alr PF04777.8 EKG14603.1 - 1.4e-27 95.4 0.6 2.4e-27 94.6 0.4 1.4 1 1 0 1 1 1 1 Erv1 / Alr family Aminotran_4 PF01063.14 EKG14604.1 - 2.2e-24 86.2 0.0 2.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MFS_1 PF07690.11 EKG14605.1 - 2.7e-39 134.8 52.2 2.7e-39 134.8 36.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG14605.1 - 1.6e-09 36.5 29.0 2.2e-09 36.0 20.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SeqA PF03925.8 EKG14608.1 - 0.00095 18.9 2.0 0.0011 18.6 1.4 1.2 1 0 0 1 1 1 1 SeqA protein Hamartin PF04388.7 EKG14608.1 - 0.019 13.6 5.0 0.021 13.5 3.5 1.0 1 0 0 1 1 1 0 Hamartin protein Abhydrolase_5 PF12695.2 EKG14610.1 - 9.1e-23 80.6 0.0 1.2e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG14610.1 - 2e-19 70.4 0.0 5.3e-18 65.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG14610.1 - 4.2e-06 26.4 0.0 0.00014 21.5 0.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKG14610.1 - 4.2e-05 23.1 0.0 0.084 12.3 0.1 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 EKG14610.1 - 5.7e-05 21.7 0.2 0.34 9.3 0.1 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 EKG14610.1 - 7.7e-05 22.2 0.0 0.00015 21.2 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EKG14610.1 - 0.00046 19.4 0.0 0.0019 17.4 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EKG14610.1 - 0.0005 19.8 0.2 0.037 13.7 0.0 2.8 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EKG14610.1 - 0.00066 19.3 0.0 0.00091 18.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EKG14610.1 - 0.0011 17.8 0.1 0.0015 17.3 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 EKG14610.1 - 0.079 12.2 0.0 2 7.6 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2305 PF10230.4 EKG14610.1 - 0.1 12.0 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EKG14610.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Proteasome PF00227.21 EKG14611.1 - 1e-47 161.9 0.3 1.1e-47 161.7 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 EKG14612.1 - 3.1e-40 138.0 1.1 1.5e-22 80.5 0.1 2.3 2 0 0 2 2 2 2 Cyclin Peptidase_M48 PF01435.13 EKG14613.1 - 8.7e-50 169.3 0.0 1.4e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EKG14613.1 - 0.0036 16.3 0.7 0.012 14.5 0.4 1.7 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.4 EKG14613.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Peptidase_M57 PF12388.3 EKG14613.1 - 0.033 13.5 0.1 0.07 12.4 0.0 1.5 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase RNA_polI_A14 PF08203.6 EKG14614.1 - 1.1e-05 25.6 0.1 3.5e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Sec10 PF07393.6 EKG14615.1 - 1.7e-162 542.2 0.1 1.7e-162 542.2 0.1 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec10 SWIB PF02201.13 EKG14615.1 - 2.4e-24 84.8 0.3 7.6e-24 83.1 0.2 2.0 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EKG14615.1 - 1.2e-12 47.3 0.2 4.7e-12 45.4 0.1 2.1 2 0 0 2 2 2 1 DEK C terminal domain Vps53_N PF04100.7 EKG14615.1 - 0.013 14.2 0.0 0.044 12.5 0.0 1.8 2 0 0 2 2 2 0 Vps53-like, N-terminal Securin PF04856.8 EKG14616.1 - 0.018 14.7 4.2 0.26 10.9 0.7 2.9 2 1 0 2 2 2 0 Securin sister-chromatid separation inhibitor Tropomyosin_1 PF12718.2 EKG14617.1 - 8.6e-51 171.5 34.3 1e-50 171.3 23.8 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EKG14617.1 - 7.1e-11 41.6 32.0 1.4e-06 27.5 3.3 3.0 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.1 EKG14617.1 - 0.0018 17.5 28.7 0.0034 16.5 19.9 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding ERM PF00769.14 EKG14617.1 - 0.0028 17.2 32.6 0.033 13.7 8.2 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Mod_r PF07200.8 EKG14617.1 - 0.0049 16.8 24.0 0.13 12.1 0.3 2.2 1 1 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein CENP-F_leu_zip PF10473.4 EKG14617.1 - 0.0054 16.5 30.0 0.0076 16.1 1.8 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EKG14617.1 - 0.0055 14.5 32.1 0.014 13.1 20.8 1.6 1 1 0 1 1 1 1 Myosin tail KLRAQ PF10205.4 EKG14617.1 - 0.0097 15.9 18.8 0.028 14.4 5.8 2.6 1 1 2 3 3 3 1 Predicted coiled-coil domain-containing protein LRS4 PF10422.4 EKG14617.1 - 0.017 14.4 14.8 0.034 13.4 10.3 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Striatin PF08232.7 EKG14617.1 - 0.018 15.3 22.2 0.023 15.0 4.7 2.1 1 1 1 2 2 2 0 Striatin family bZIP_1 PF00170.16 EKG14617.1 - 0.033 14.1 0.9 0.033 14.1 0.6 4.3 1 1 2 4 4 4 0 bZIP transcription factor ATG16 PF08614.6 EKG14617.1 - 0.034 13.9 26.7 0.24 11.1 10.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Herpes_pp85 PF04637.7 EKG14617.1 - 0.044 12.0 3.1 0.042 12.1 1.6 1.3 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Seryl_tRNA_N PF02403.17 EKG14617.1 - 0.047 13.7 26.3 0.15 12.1 0.2 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EKG14617.1 - 0.071 12.6 27.7 1.6 8.2 19.2 2.2 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 EKG14617.1 - 0.076 12.0 31.5 0.24 10.3 12.9 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Laminin_II PF06009.7 EKG14617.1 - 0.13 12.0 15.8 0.038 13.7 2.2 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF3287 PF11690.3 EKG14617.1 - 0.18 11.9 7.5 0.086 12.9 0.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) Rab5-bind PF09311.6 EKG14617.1 - 0.2 11.5 24.4 0.26 11.1 16.9 1.2 1 0 0 1 1 1 0 Rabaptin-like protein TPR_MLP1_2 PF07926.7 EKG14617.1 - 0.22 11.2 32.1 0.19 11.4 7.4 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 EKG14617.1 - 0.22 11.6 18.3 1.4 9.0 4.8 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 EKG14617.1 - 0.23 9.2 15.2 0.32 8.7 10.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 EKG14617.1 - 0.31 10.1 4.1 0.95 8.5 0.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 EKG14617.1 - 0.34 10.3 24.1 2 7.8 15.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) IFT46_B_C PF12317.3 EKG14617.1 - 0.35 10.1 7.5 0.12 11.7 2.8 1.7 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Jnk-SapK_ap_N PF09744.4 EKG14617.1 - 0.36 10.7 24.9 0.35 10.8 10.8 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ADIP PF11559.3 EKG14617.1 - 0.36 10.7 28.7 2.6 7.9 7.6 3.0 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 EKG14617.1 - 0.39 11.1 20.2 1.5 9.2 4.2 2.5 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.1 EKG14617.1 - 0.64 8.4 23.9 1.2 7.4 4.7 2.0 1 1 1 2 2 2 0 AAA domain CCDC155 PF14662.1 EKG14617.1 - 0.67 9.5 29.1 0.77 9.3 6.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 EKG14617.1 - 1 9.4 16.5 1.1 9.4 2.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 EKG14617.1 - 1.2 8.0 24.1 0.18 10.6 11.4 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 EKG14617.1 - 1.2 7.5 23.3 0.69 8.2 6.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FlaC_arch PF05377.6 EKG14617.1 - 1.2 9.1 16.8 1.5 8.7 1.7 4.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.3 EKG14617.1 - 1.5 8.5 25.5 18 5.0 2.5 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EKG14617.1 - 2.6 7.9 33.7 1.8 8.4 9.9 3.7 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WXG100 PF06013.7 EKG14617.1 - 2.8 7.9 12.5 5.2 7.1 0.1 3.6 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Spc7 PF08317.6 EKG14617.1 - 2.8 6.4 24.9 0.25 9.9 9.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4559 PF15112.1 EKG14617.1 - 2.9 6.9 14.0 3.8 6.5 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3584 PF12128.3 EKG14617.1 - 3 5.0 24.3 4.9 4.3 16.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.3 EKG14617.1 - 3.3 6.9 22.5 5 6.3 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 EKG14617.1 - 3.4 8.0 21.8 1.7 9.0 7.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 EKG14617.1 - 3.7 7.8 7.8 59 4.0 2.2 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein BRE1 PF08647.6 EKG14617.1 - 4.9 7.1 27.5 7.6 6.5 10.3 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase GCN5L1 PF06320.8 EKG14617.1 - 5.5 6.8 15.1 2.1 8.1 5.1 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) FUSC PF04632.7 EKG14617.1 - 7.6 4.8 6.9 9.3 4.5 4.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lectin_N PF03954.9 EKG14617.1 - 7.6 5.9 9.9 8.4 5.7 3.2 2.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Ax_dynein_light PF10211.4 EKG14617.1 - 9 6.0 28.9 6.5 6.5 4.9 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain rRNA_proc-arch PF13234.1 EKG14617.1 - 9.7 5.2 16.4 0.26 10.4 1.2 2.4 1 1 0 2 2 2 0 rRNA-processing arch domain DUF948 PF06103.6 EKG14617.1 - 9.8 6.1 9.7 22 4.9 2.0 2.8 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Nop25 PF09805.4 EKG14618.1 - 9.9e-36 122.8 17.8 9.9e-36 122.8 12.4 3.2 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) Peptidase_M20 PF01546.23 EKG14619.1 - 1.1e-21 77.2 0.0 1.4e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EKG14619.1 - 4.9e-17 61.6 0.1 2.7e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EKG14619.1 - 0.0035 17.1 0.5 0.0051 16.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Mycobact_memb PF05423.8 EKG14619.1 - 0.055 13.2 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Mycobacterium membrane protein Erv26 PF04148.8 EKG14620.1 - 2.6e-90 301.4 2.9 2.9e-90 301.2 2.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TMEM173 PF15009.1 EKG14620.1 - 0.19 10.4 0.9 0.35 9.6 0.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 173 WBS_methylT PF12589.3 EKG14621.1 - 6.8e-18 64.9 7.1 1.1e-17 64.2 4.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EKG14621.1 - 0.00047 20.5 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ACT_7 PF13840.1 EKG14621.1 - 0.089 12.3 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 ACT domain Iso_dh PF00180.15 EKG14622.1 - 2.3e-84 283.3 0.0 2.9e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.11 EKG14623.1 - 3.3e-19 68.8 16.5 2.2e-15 56.2 4.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_tranf_2_3 PF13641.1 EKG14625.1 - 2.5e-25 89.6 0.0 3.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EKG14625.1 - 5.1e-20 71.9 6.3 5.1e-20 71.9 4.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EKG14625.1 - 7e-06 25.4 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EKG14625.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Acyl_transf_3 PF01757.17 EKG14626.1 - 1.5e-09 37.1 40.8 1.5e-09 37.1 28.2 2.0 2 0 0 2 2 2 1 Acyltransferase family Glyco_hydro_16 PF00722.16 EKG14626.1 - 2.6e-08 33.3 0.9 4.2e-08 32.7 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Far-17a_AIG1 PF04750.9 EKG14628.1 - 7.8e-55 185.1 8.7 8.9e-55 184.9 6.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Fungal_trans_2 PF11951.3 EKG14629.1 - 1.8e-60 204.5 0.0 2.8e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rac1 PF09632.5 EKG14630.1 - 0.19 10.8 1.0 0.27 10.2 0.7 1.2 1 0 0 1 1 1 0 Rac1-binding domain CCDC92 PF14916.1 EKG14630.1 - 0.28 10.7 5.5 0.58 9.7 3.6 1.7 1 1 0 1 1 1 0 Coiled-coil domain of unknown function HR1 PF02185.11 EKG14630.1 - 0.29 10.9 5.1 12 5.7 3.7 2.8 2 1 0 2 2 2 0 Hr1 repeat Rootletin PF15035.1 EKG14630.1 - 0.3 11.0 5.9 0.52 10.2 4.1 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.6 EKG14630.1 - 0.31 9.6 4.6 0.46 9.0 3.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PPP1R35_C PF15503.1 EKG14630.1 - 0.51 9.8 4.3 1.5 8.3 0.0 2.4 2 1 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus FliJ PF02050.11 EKG14630.1 - 0.53 10.3 10.0 1 9.4 7.0 1.4 1 0 0 1 1 1 0 Flagellar FliJ protein GBP_C PF02841.9 EKG14630.1 - 0.95 8.5 7.2 0.059 12.5 1.4 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF904 PF06005.7 EKG14630.1 - 1.3 9.3 8.8 0.6 10.4 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Atg14 PF10186.4 EKG14630.1 - 2 7.2 6.3 3.4 6.5 4.4 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EKG14630.1 - 4.6 6.7 9.2 2.2 7.8 4.8 1.6 2 0 0 2 2 2 0 IncA protein MHC_I PF00129.13 EKG14632.1 - 0.00047 19.5 0.5 0.0015 17.9 0.1 1.7 1 1 1 2 2 2 1 Class I Histocompatibility antigen, domains alpha 1 and 2 DUF484 PF04340.7 EKG14632.1 - 0.002 17.6 6.5 0.0024 17.3 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF484 WXG100 PF06013.7 EKG14632.1 - 0.041 13.8 6.1 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Chordopox_A30L PF06015.7 EKG14632.1 - 0.045 13.3 0.5 0.17 11.4 0.1 1.9 1 1 1 2 2 2 0 Chordopoxvirus A30L protein Phage_connect_1 PF05135.8 EKG14632.1 - 0.084 13.0 0.5 0.12 12.5 0.4 1.4 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein Enkurin PF13864.1 EKG14632.1 - 0.14 12.3 4.7 0.17 12.0 2.3 2.0 1 1 0 1 1 1 0 Calmodulin-binding Kinetocho_Slk19 PF12709.2 EKG14632.1 - 0.15 12.1 5.7 1.7 8.7 2.1 2.4 1 1 1 2 2 2 0 Central kinetochore-associated Fib_alpha PF08702.5 EKG14632.1 - 0.16 12.0 2.0 0.21 11.7 1.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF826 PF05696.6 EKG14632.1 - 0.21 11.7 1.4 0.42 10.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF826) ATP11 PF06644.6 EKG14633.1 - 4.5e-80 268.9 0.0 5.2e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein SseB PF07179.7 EKG14633.1 - 0.0084 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 SseB protein N-terminal domain 4HBT_3 PF13622.1 EKG14633.1 - 0.09 12.5 1.2 0.13 12.0 0.9 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF883 PF05957.8 EKG14633.1 - 0.15 12.4 0.8 0.26 11.7 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) GHMP_kinases_N PF00288.21 EKG14634.1 - 1.6e-19 69.7 0.1 4e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EKG14634.1 - 2.6e-08 33.9 0.0 6.8e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EKG14634.1 - 0.029 13.6 0.1 0.099 11.9 0.0 1.9 2 0 0 2 2 2 0 Galactokinase galactose-binding signature Acetyltransf_3 PF13302.1 EKG14635.1 - 2.8e-26 92.3 0.0 5e-26 91.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG14635.1 - 2.2e-07 30.8 0.0 1.1e-05 25.4 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EKG14635.1 - 4e-07 30.0 0.7 0.0013 18.5 0.2 3.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG14635.1 - 0.0015 18.4 0.0 0.095 12.6 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG14635.1 - 0.0016 18.1 0.1 0.68 9.7 0.0 2.3 1 1 1 2 2 2 2 FR47-like protein Tubulin-binding PF00418.14 EKG14635.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat 3Beta_HSD PF01073.14 EKG14636.1 - 1.7e-25 89.3 0.0 1.9e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKG14636.1 - 2e-22 79.7 0.0 2.2e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG14636.1 - 3e-12 46.0 0.0 3.9e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EKG14636.1 - 4.9e-12 46.0 0.2 8.5e-12 45.3 0.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EKG14636.1 - 5.1e-11 41.9 0.2 2.9e-06 26.4 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein KR PF08659.5 EKG14636.1 - 1.7e-07 31.1 1.0 2.2e-06 27.4 0.7 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG14636.1 - 5.7e-07 29.7 0.0 6.7e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EKG14636.1 - 7.7e-07 28.2 0.3 3.3e-06 26.2 0.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Tetraspannin PF00335.15 EKG14637.1 - 0.0036 16.5 2.0 0.0036 16.5 1.4 1.4 1 1 0 1 1 1 1 Tetraspanin family DUF202 PF02656.10 EKG14637.1 - 0.0093 16.1 2.9 2.6 8.3 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF202) MARVEL PF01284.18 EKG14637.1 - 0.021 14.6 8.9 0.031 14.0 5.5 1.7 1 1 1 2 2 2 0 Membrane-associating domain DUF4271 PF14093.1 EKG14637.1 - 0.022 14.4 1.5 0.034 13.8 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) 7TMR-DISM_7TM PF07695.6 EKG14637.1 - 0.047 13.3 3.6 0.096 12.3 2.5 1.4 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF1218 PF06749.7 EKG14637.1 - 2.4 8.6 9.0 1.9 8.9 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Inhibitor_Mig-6 PF11555.3 EKG14638.1 - 0.019 15.3 3.9 0.019 15.3 2.7 2.7 2 1 1 3 3 3 0 EGFR receptor inhibitor Mig-6 Enolase_C PF00113.17 EKG14640.1 - 1.1e-154 513.7 0.0 1.4e-154 513.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EKG14640.1 - 2.5e-59 198.9 0.4 5.4e-59 197.8 0.3 1.6 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EKG14640.1 - 0.00031 19.7 0.6 0.026 13.4 0.2 2.9 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EKG14640.1 - 0.019 14.9 0.2 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like MR_MLE PF01188.16 EKG14640.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain AAA PF00004.24 EKG14641.1 - 1.4e-42 145.0 0.0 2.3e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG14641.1 - 1.1e-07 32.0 0.0 6.2e-06 26.3 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EKG14641.1 - 1.6e-06 27.8 0.1 3.8e-05 23.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKG14641.1 - 2.3e-06 27.6 0.0 7.7e-06 25.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EKG14641.1 - 3e-06 27.4 0.0 0.001 19.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EKG14641.1 - 7.5e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EKG14641.1 - 0.0003 19.7 0.0 0.00064 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EKG14641.1 - 0.00032 20.3 0.0 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EKG14641.1 - 0.00051 20.8 0.6 0.0022 18.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EKG14641.1 - 0.0014 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EKG14641.1 - 0.0018 17.1 0.0 0.0031 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EKG14641.1 - 0.0019 18.0 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG14641.1 - 0.0027 18.0 0.1 0.0084 16.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EKG14641.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EKG14641.1 - 0.0036 16.4 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EKG14641.1 - 0.0051 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EKG14641.1 - 0.0055 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EKG14641.1 - 0.0076 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EKG14641.1 - 0.0091 15.4 0.1 0.047 13.0 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EKG14641.1 - 0.0098 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EKG14641.1 - 0.02 14.4 0.1 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKG14641.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EKG14641.1 - 0.024 14.6 0.0 0.064 13.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EKG14641.1 - 0.027 14.1 0.1 0.14 11.8 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 EKG14641.1 - 0.027 13.5 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC ResIII PF04851.10 EKG14641.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EKG14641.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EKG14641.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EKG14641.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Thymidylate_kin PF02223.12 EKG14641.1 - 0.054 12.8 0.0 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 Thymidylate kinase AAA_11 PF13086.1 EKG14641.1 - 0.075 12.6 0.1 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EKG14641.1 - 0.079 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EKG14641.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RAMP4 PF06624.7 EKG14642.1 - 0.062 12.8 6.8 1.1 8.8 4.7 2.0 1 1 0 1 1 1 0 Ribosome associated membrane protein RAMP4 EXS PF03124.9 EKG14643.1 - 7.4e-95 317.8 1.4 8.6e-95 317.6 1.0 1.0 1 0 0 1 1 1 1 EXS family HhH-GPD PF00730.20 EKG14646.1 - 0.038 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein Glyco_transf_20 PF00982.16 EKG14650.1 - 1.3e-160 535.0 0.4 1.5e-160 534.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EKG14650.1 - 4.4e-46 156.6 0.0 7.3e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase TFIID_90kDa PF04494.10 EKG14650.1 - 0.0025 17.8 0.3 0.018 15.0 0.1 2.4 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit Hydrolase_3 PF08282.7 EKG14650.1 - 0.041 13.4 0.0 0.5 9.9 0.0 2.3 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Fcf2 PF08698.6 EKG14652.1 - 9.1e-35 118.6 2.3 9.1e-35 118.6 1.6 2.0 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing DUF2518 PF10726.4 EKG14652.1 - 0.38 10.2 1.4 0.38 10.2 0.2 1.5 2 0 0 2 2 2 0 Protein of function (DUF2518) DUF1843 PF08898.5 EKG14652.1 - 1.1 9.3 5.0 20 5.3 0.6 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) FKBP_N PF01346.13 EKG14652.1 - 5.9 6.9 11.7 0.088 12.8 0.5 2.8 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase HlyIII PF03006.15 EKG14653.1 - 3.6e-58 196.6 24.1 4.5e-58 196.2 16.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Rav1p_C PF12234.3 EKG14653.1 - 0.089 10.9 0.1 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal DUF373 PF04123.8 EKG14653.1 - 0.13 11.2 2.5 0.24 10.3 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF373) FimP PF09766.4 EKG14654.1 - 2.7e-21 76.0 15.7 3.2e-20 72.5 10.9 2.0 1 1 0 1 1 1 1 Fms-interacting protein DUF948 PF06103.6 EKG14654.1 - 0.39 10.5 1.5 5.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GCN5L1 PF06320.8 EKG14654.1 - 0.65 9.8 5.9 0.074 12.8 0.5 2.1 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) Y_phosphatase3 PF13350.1 EKG14655.1 - 6.4e-28 98.0 0.0 1e-15 58.3 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EKG14655.1 - 9.4e-06 25.6 0.1 4.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EKG14655.1 - 0.00025 20.4 0.0 0.0005 19.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF3812 PF12757.2 EKG14656.1 - 8.3e-41 138.9 14.3 8.3e-41 138.9 9.9 4.5 2 2 2 4 4 4 1 Protein of unknown function (DUF3812) Pkinase PF00069.20 EKG14657.1 - 6.4e-60 202.4 0.0 7.7e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG14657.1 - 2.8e-33 115.0 0.0 3.7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4520 PF15016.1 EKG14657.1 - 0.024 14.1 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) CbiZ PF01955.13 EKG14657.1 - 0.029 14.1 0.4 0.046 13.5 0.3 1.2 1 0 0 1 1 1 0 Adenosylcobinamide amidohydrolase Kinase-like PF14531.1 EKG14657.1 - 0.076 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like IGR PF09597.5 EKG14658.1 - 3.5e-23 81.2 0.0 5.8e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif AAA PF00004.24 EKG14659.1 - 4.9e-17 62.3 0.0 9.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) S4 PF01479.20 EKG14659.1 - 0.022 14.1 0.0 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 S4 domain Nop14 PF04147.7 EKG14660.1 - 2.4 5.9 38.6 0.046 11.6 19.5 2.1 2 0 0 2 2 2 0 Nop14-like family Cnd2 PF05786.9 EKG14661.1 - 7e-223 742.2 15.0 8.1e-223 742.0 10.4 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 ScpA_ScpB PF02616.9 EKG14661.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 ScpA/B protein Na_Ca_ex PF01699.19 EKG14662.1 - 1.7e-47 160.5 28.8 1e-27 96.4 2.6 3.1 3 0 0 3 3 3 2 Sodium/calcium exchanger protein AAA_16 PF13191.1 EKG14663.1 - 8.7e-13 48.6 0.4 5.2e-11 42.8 0.3 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG14663.1 - 6.9e-11 42.4 0.0 2.2e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKG14663.1 - 1.9e-09 37.7 0.0 7.1e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKG14663.1 - 2.4e-05 24.1 0.7 9.3e-05 22.2 0.1 2.2 2 1 0 2 2 2 1 Archaeal ATPase Cdc6_C PF09079.6 EKG14663.1 - 3.5e-05 23.4 0.0 9.4e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal AAA_17 PF13207.1 EKG14663.1 - 0.00038 21.2 0.0 0.00086 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKG14663.1 - 0.00072 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EKG14663.1 - 0.0017 17.3 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EKG14663.1 - 0.0026 17.4 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EKG14663.1 - 0.0031 17.6 0.0 0.0088 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Helicase_RecD PF05127.9 EKG14663.1 - 0.01 15.4 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 0 Helicase AAA_28 PF13521.1 EKG14663.1 - 0.015 15.2 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EKG14663.1 - 0.018 14.7 0.0 0.047 13.3 0.0 1.7 2 0 0 2 2 1 0 NTPase AAA_11 PF13086.1 EKG14663.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EKG14663.1 - 0.021 14.5 0.0 0.086 12.5 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 EKG14663.1 - 0.021 13.7 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EKG14663.1 - 0.027 13.2 0.0 0.044 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus PIF1 PF05970.9 EKG14663.1 - 0.035 13.0 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase T2SE PF00437.15 EKG14663.1 - 0.036 12.9 0.1 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein RuvB_N PF05496.7 EKG14663.1 - 0.048 12.6 0.0 0.19 10.7 0.0 2.0 1 1 1 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 EKG14663.1 - 0.049 14.1 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Rad17 PF03215.10 EKG14663.1 - 0.05 12.2 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EKG14663.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKG14663.1 - 0.067 12.9 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Thg1C PF14413.1 EKG14663.1 - 0.072 12.7 0.0 0.23 11.1 0.0 1.8 1 0 0 1 1 1 0 Thg1 C terminal domain AAA_35 PF14516.1 EKG14663.1 - 0.19 10.3 0.7 0.51 8.9 0.0 2.0 3 0 0 3 3 3 0 AAA-like domain PPV_E1_C PF00519.12 EKG14663.1 - 0.2 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Sod_Fe_C PF02777.13 EKG14664.1 - 1.2e-11 44.4 0.1 0.00015 21.5 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Polyketide_cyc PF03364.15 EKG14666.1 - 2.3e-17 63.1 0.3 4.5e-16 59.0 0.2 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EKG14666.1 - 0.0034 17.5 0.8 0.041 14.0 0.2 2.4 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.7 EKG14667.1 - 5.4e-13 49.2 0.0 1.2e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG14667.1 - 1.2e-10 41.7 0.0 2.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG14667.1 - 6.7e-10 38.9 0.0 2.6e-09 36.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG14667.1 - 6.4e-09 36.3 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG14667.1 - 6.4e-08 32.8 0.0 1.4e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG14667.1 - 1.1e-06 28.2 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG14667.1 - 1.4e-06 27.6 0.0 4.2e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EKG14667.1 - 9.9e-06 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EKG14667.1 - 0.0061 15.5 0.0 0.21 10.5 0.0 2.2 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family DUF3419 PF11899.3 EKG14667.1 - 0.032 12.9 0.0 0.049 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_24 PF13578.1 EKG14667.1 - 0.053 14.3 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EKG14667.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.9 EKG14667.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EKG14667.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ABC_membrane PF00664.18 EKG14668.1 - 5.3e-53 180.1 36.5 4.5e-32 111.5 13.4 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EKG14668.1 - 1.3e-47 161.5 0.0 1e-27 97.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKG14668.1 - 1.2e-06 28.7 0.1 1.8 8.4 0.0 4.5 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EKG14668.1 - 3.5e-05 22.9 0.0 0.019 14.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 EKG14668.1 - 3.9e-05 23.5 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EKG14668.1 - 4.8e-05 22.8 0.4 0.12 11.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG14668.1 - 6.6e-05 22.9 0.1 0.57 10.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EKG14668.1 - 0.00013 22.8 0.0 0.27 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EKG14668.1 - 0.00015 21.0 0.8 1.6 7.9 0.1 3.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 EKG14668.1 - 0.0003 21.2 1.7 0.71 10.3 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EKG14668.1 - 0.00064 18.9 1.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 EKG14668.1 - 0.0024 17.7 2.3 0.098 12.4 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EKG14668.1 - 0.0027 17.8 0.7 4 7.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKG14668.1 - 0.006 16.0 0.0 0.98 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain T2SE PF00437.15 EKG14668.1 - 0.0088 14.9 0.0 2.3 7.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EKG14668.1 - 0.02 14.2 0.1 4.1 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EKG14668.1 - 0.028 13.9 0.3 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EKG14668.1 - 0.031 14.5 7.3 3 8.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 EKG14668.1 - 0.046 14.0 0.6 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EKG14668.1 - 0.069 12.6 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EKG14668.1 - 0.07 12.8 0.4 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EKG14668.1 - 0.096 11.4 0.5 7 5.3 0.1 2.4 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EKG14668.1 - 0.14 11.9 9.8 0.078 12.7 0.1 3.1 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EKG14668.1 - 0.15 11.5 2.3 9.4 5.6 0.1 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Aminotran_3 PF00202.16 EKG14669.1 - 7.6e-104 347.1 0.0 9.5e-104 346.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EKG14669.1 - 0.00013 21.2 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EKG14669.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II AAA PF00004.24 EKG14670.1 - 5e-15 55.8 0.0 1.3e-14 54.5 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG14670.1 - 0.007 16.5 0.0 0.033 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKG14670.1 - 0.019 15.1 0.0 0.093 12.9 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Bac_DnaA PF00308.13 EKG14670.1 - 0.038 13.6 0.0 0.099 12.2 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.1 EKG14670.1 - 0.072 13.0 0.0 0.3 11.0 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain Zn_clus PF00172.13 EKG14671.1 - 2.1e-05 24.3 8.1 2.1e-05 24.3 5.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dsl1_C PF11989.3 EKG14672.1 - 1.5e-10 40.7 0.0 4.3e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.8 EKG14672.1 - 1.6e-10 39.7 0.1 4.2e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Tropomyosin_1 PF12718.2 EKG14672.1 - 0.0061 16.4 1.2 0.0061 16.4 0.8 2.8 2 0 0 2 2 2 1 Tropomyosin like Peptidase_M16_C PF05193.16 EKG14673.1 - 2.4e-24 86.0 0.0 1.5e-17 63.8 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EKG14673.1 - 5e-06 26.3 0.0 0.00011 22.0 0.0 2.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Nucleoplasmin PF03066.10 EKG14673.1 - 0.0091 15.5 8.2 0.02 14.3 5.7 1.6 1 0 0 1 1 1 1 Nucleoplasmin DUF2205 PF10224.4 EKG14673.1 - 0.072 12.6 3.2 0.14 11.7 1.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) M16C_assoc PF08367.6 EKG14673.1 - 0.085 11.6 2.1 7.2 5.3 0.2 2.5 2 1 0 2 2 2 0 Peptidase M16C associated PMM PF03332.8 EKG14674.1 - 3.2e-103 344.0 0.1 3.8e-103 343.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TMPIT PF07851.8 EKG14674.1 - 0.023 13.7 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Hydrolase_3 PF08282.7 EKG14674.1 - 0.098 12.2 0.0 1.2 8.7 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_21 PF09976.4 EKG14675.1 - 0.33 10.8 3.1 0.41 10.5 2.2 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 EKG14676.1 - 1.9e-82 275.6 0.1 3e-82 275.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EKG14676.1 - 3.4e-68 228.9 0.0 6.2e-68 228.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EKG14676.1 - 4.6e-35 120.0 0.0 1.2e-34 118.6 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EKG14676.1 - 1.2e-31 108.8 0.0 3.1e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EKG14676.1 - 2e-29 102.9 0.1 4.2e-29 101.8 0.0 1.6 1 1 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EKG14676.1 - 7.6e-19 67.1 2.3 1.9e-18 65.8 1.3 1.9 2 0 0 2 2 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EKG14676.1 - 6.4e-18 65.1 0.1 1.5e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG14676.1 - 2.2e-15 56.2 0.0 1.2e-14 53.8 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EKG14676.1 - 4.8e-11 42.4 0.0 9.6e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EKG14676.1 - 1.1e-10 40.9 1.9 1.6e-07 30.8 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EKG14676.1 - 1.6e-07 30.8 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EKG14676.1 - 2.5e-07 30.3 0.0 7.7e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EKG14676.1 - 3.1e-06 27.1 0.0 6.9e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EKG14676.1 - 6.1e-05 22.4 0.2 0.00071 18.9 0.1 2.3 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EKG14676.1 - 7e-05 23.1 0.1 0.01 16.1 0.1 3.6 2 1 1 3 3 3 2 HlyD family secretion protein HlyD_2 PF12700.2 EKG14676.1 - 0.00032 19.9 0.1 0.39 9.8 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 EKG14676.1 - 0.0083 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SUI1 PF01253.17 EKG14676.1 - 0.033 13.9 0.0 6.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor SUI1 Clathrin PF00637.15 EKG14677.1 - 3.9e-205 671.6 31.8 1.1e-35 122.3 1.3 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EKG14677.1 - 7.1e-32 109.1 3.5 7.6e-32 109.0 0.8 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 EKG14677.1 - 4.8e-30 101.7 3.9 4.4e-05 23.4 0.0 7.6 7 0 0 7 7 7 5 Clathrin propeller repeat Vps39_1 PF10366.4 EKG14677.1 - 4.9e-05 23.3 7.4 3.8 7.5 0.0 6.1 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 Ank_3 PF13606.1 EKG14677.1 - 0.0028 17.7 0.0 0.54 10.6 0.0 3.8 3 0 0 3 3 2 1 Ankyrin repeat Coatomer_WDAD PF04053.9 EKG14677.1 - 0.012 14.3 10.2 0.051 12.3 0.4 4.6 5 0 0 5 5 5 0 Coatomer WD associated region Clathrin-link PF09268.5 EKG14677.1 - 0.013 14.5 0.3 0.04 12.9 0.2 1.9 1 0 0 1 1 1 0 Clathrin, heavy-chain linker TPR_1 PF00515.23 EKG14677.1 - 0.019 14.5 0.7 5.7 6.7 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EKG14677.1 - 0.024 14.3 5.1 28 4.8 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EKG14677.1 - 0.034 14.0 8.7 5.5 6.9 0.0 6.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKG14677.1 - 0.3 11.1 8.1 6.2 7.0 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG14677.1 - 1.2 10.0 18.8 10 7.0 0.1 8.9 12 0 0 12 12 9 0 Tetratricopeptide repeat eIF3_subunit PF08597.5 EKG14678.1 - 1.5e-67 227.7 30.4 1.6e-67 227.6 21.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit YL1 PF05764.8 EKG14678.1 - 3.1 7.3 29.9 0.22 11.1 14.5 2.1 2 0 0 2 2 2 0 YL1 nuclear protein FAM60A PF15396.1 EKG14678.1 - 5.9 6.5 10.0 0.86 9.3 2.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Activator_LAG-3 PF11498.3 EKG14678.1 - 6 5.5 9.3 8.9 4.9 6.4 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 V_ATPase_I PF01496.14 EKG14678.1 - 7 4.3 6.9 8.5 4.0 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FNIP_N PF14636.1 EKG14678.1 - 7.2 7.0 7.6 1.3 9.4 1.6 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Fcf1 PF04900.7 EKG14679.1 - 5.9e-41 138.6 0.3 1.1e-40 137.8 0.2 1.4 1 0 0 1 1 1 1 Fcf1 SAPS PF04499.10 EKG14680.1 - 0.1 11.1 0.3 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2763 PF10961.3 EKG14680.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2763) Menin PF05053.8 EKG14680.1 - 3.4 5.7 10.8 5.5 5.0 7.5 1.3 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 EKG14680.1 - 5.1 5.2 16.5 7.2 4.7 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Podoplanin PF05808.6 EKG14680.1 - 7.4 6.0 19.8 14 5.2 13.7 1.4 1 0 0 1 1 1 0 Podoplanin LEA_6 PF10714.4 EKG14681.1 - 1.1 9.1 4.7 0.59 9.9 0.5 2.3 1 1 1 2 2 2 0 Late embryogenesis abundant protein 18 ArfGap PF01412.13 EKG14682.1 - 2e-38 130.7 2.9 3.4e-38 130.0 0.1 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 EKG14682.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain PhoD PF09423.5 EKG14683.1 - 5.1e-07 28.6 0.9 8.3e-07 27.9 0.5 1.4 2 0 0 2 2 2 1 PhoD-like phosphatase Chlorosome_CsmC PF11098.3 EKG14683.1 - 0.046 13.4 2.4 0.09 12.4 1.7 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF1640 PF07798.6 EKG14684.1 - 1.4e-48 165.2 6.3 1.5e-48 165.1 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Syntaxin PF00804.20 EKG14684.1 - 0.078 13.1 7.8 0.25 11.5 5.3 1.8 1 1 0 1 1 1 0 Syntaxin 14-3-3 PF00244.15 EKG14685.1 - 9.7e-115 381.5 0.6 1.2e-114 381.3 0.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 EKG14685.1 - 0.0044 16.9 0.2 4.6 7.2 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF837 PF05769.6 EKG14685.1 - 0.064 12.7 0.5 12 5.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF4085 PF13315.1 EKG14685.1 - 0.085 12.2 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HisKA PF00512.20 EKG14685.1 - 0.11 12.5 1.4 10 6.1 0.0 3.3 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain WD40 PF00400.27 EKG14686.1 - 1.5e-31 107.1 15.6 1.4e-06 27.9 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EKG14686.1 - 2.3e-19 69.1 0.2 3.4e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EKG14686.1 - 9e-07 27.3 6.8 0.0034 15.5 0.1 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Trm112p PF03966.11 EKG14687.1 - 3.8e-15 56.0 0.2 6.6e-15 55.2 0.1 1.4 1 1 0 1 1 1 1 Trm112p-like protein DUF1451 PF07295.6 EKG14687.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Rad60-SLD PF11976.3 EKG14688.1 - 1.9e-14 53.0 0.0 5.3e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like BTB_2 PF02214.17 EKG14688.1 - 0.018 15.2 0.3 0.04 14.1 0.2 1.5 1 0 0 1 1 1 0 BTB/POZ domain LSM PF01423.17 EKG14689.1 - 1.3e-19 69.4 0.0 1.4e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKG14689.1 - 0.0005 19.9 0.1 0.00056 19.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain UnbV_ASPIC PF07593.7 EKG14689.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 ASPIC and UnbV DUF1106 PF06523.6 EKG14689.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Secretin_N_2 PF07655.8 EKG14691.1 - 0.15 12.4 5.2 0.25 11.7 3.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain C1_1 PF00130.17 EKG14693.1 - 0.019 14.6 2.7 0.019 14.6 1.9 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Erf4 PF10256.4 EKG14694.1 - 0.00072 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family GSG-1 PF07803.6 EKG14695.1 - 0.043 13.4 1.3 0.068 12.7 0.9 1.3 1 1 0 1 1 1 0 GSG1-like protein Pro_isomerase PF00160.16 EKG14696.1 - 2.9e-48 163.9 0.1 6e-48 162.9 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EKG14696.1 - 2.7e-15 55.5 0.4 2.2e-08 33.6 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EKG14696.1 - 0.0039 15.3 0.0 0.0097 14.0 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin Nup120/160 G_glu_transpept PF01019.16 EKG14697.1 - 4.5e-157 523.5 0.1 5.2e-157 523.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase UCH PF00443.24 EKG14698.1 - 4.1e-26 91.6 0.0 6.1e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EKG14698.1 - 7.7e-11 41.9 0.1 1.7e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Cpn60_TCP1 PF00118.19 EKG14699.1 - 8.2e-135 450.1 9.5 9.8e-135 449.8 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 EKG14700.1 - 2.7e-42 144.7 0.0 3.9e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EKG14700.1 - 2.7e-38 130.7 0.0 1.9e-37 127.9 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EKG14700.1 - 9.3e-20 70.7 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EKG14700.1 - 4e-10 38.6 1.8 0.0012 18.2 0.0 3.7 3 0 0 3 3 3 3 PQQ enzyme repeat PQQ_2 PF13360.1 EKG14700.1 - 0.0002 20.8 0.0 0.78 9.1 0.0 2.8 3 0 0 3 3 3 2 PQQ-like domain DUF3357 PF11837.3 EKG14700.1 - 0.031 14.1 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) EF-hand_4 PF12763.2 EKG14701.1 - 2.3e-28 97.9 0.0 1e-14 54.0 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EKG14701.1 - 3.7e-13 49.3 110.5 1e-08 35.0 23.4 6.8 5 1 1 6 6 6 3 Domain of unknown function (DUF1720) WH2 PF02205.15 EKG14701.1 - 1.3e-08 34.1 0.2 4.4e-08 32.4 0.1 2.0 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EKG14701.1 - 0.0003 20.8 0.0 0.043 13.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EKG14701.1 - 0.038 13.3 0.0 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 EF hand Exonuc_VII_S PF02609.11 EKG14702.1 - 0.0026 17.4 0.2 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 Exonuclease VII small subunit DUF3620 PF12281.3 EKG14702.1 - 0.018 14.7 0.2 0.02 14.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) Baculo_PEP_C PF04513.7 EKG14702.1 - 0.078 12.8 0.1 0.095 12.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAUS-augmin3 PF14932.1 EKG14702.1 - 0.1 11.7 0.3 0.11 11.7 0.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Herpes_UL25 PF01499.11 EKG14702.1 - 0.17 10.1 1.9 0.17 10.1 1.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family FUSC PF04632.7 EKG14702.1 - 0.42 8.9 5.5 0.38 9.1 3.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family IF-2B PF01008.12 EKG14703.1 - 1.4e-72 244.0 3.2 1.7e-72 243.8 2.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Aldo_ket_red PF00248.16 EKG14704.1 - 2.7e-48 164.2 0.1 3.3e-48 163.9 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.6 EKG14704.1 - 0.015 14.6 0.1 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Poliovirus 3A protein like CoA_binding_2 PF13380.1 EKG14704.1 - 0.088 12.9 0.1 2.3 8.4 0.1 2.6 1 1 0 2 2 2 0 CoA binding domain SHR3_chaperone PF08229.6 EKG14706.1 - 1.2e-73 246.3 0.0 1.3e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Aminotran_5 PF00266.14 EKG14708.1 - 3.9e-26 91.6 0.0 5.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EKG14708.1 - 0.0031 17.2 0.0 0.017 14.8 0.0 2.2 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Arrestin_N PF00339.24 EKG14711.1 - 4.2e-16 59.1 0.0 1e-14 54.6 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKG14711.1 - 2.5e-09 37.3 0.0 4.9e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SNF2_N PF00176.18 EKG14712.1 - 2.1e-52 177.8 0.0 4.6e-52 176.6 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EKG14712.1 - 1.4e-07 31.1 11.0 2.9e-07 30.1 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKG14712.1 - 2.2e-07 30.4 6.9 4.5e-07 29.4 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG14712.1 - 7.2e-07 29.1 10.7 1.4e-06 28.2 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG14712.1 - 4.4e-05 23.0 10.0 0.0001 21.8 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG14712.1 - 0.00016 21.2 10.0 0.00033 20.3 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EKG14712.1 - 0.00024 20.5 4.7 0.00054 19.4 3.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EKG14712.1 - 0.0034 17.4 6.2 0.0084 16.2 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Helicase_C PF00271.26 EKG14712.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_4 PF14570.1 EKG14712.1 - 0.052 13.1 6.6 0.12 12.0 4.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EKG14712.1 - 0.12 12.2 10.0 0.24 11.3 7.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING UPF0547 PF10571.4 EKG14712.1 - 0.86 9.3 4.7 1.3 8.7 1.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-P11 PF03854.9 EKG14712.1 - 1.4 8.4 8.0 2.9 7.4 5.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger DZR PF12773.2 EKG14712.1 - 3.3 7.5 6.5 3.6 7.4 2.8 2.2 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.1 EKG14712.1 - 4.3 7.1 6.8 13 5.5 4.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger YTH PF04146.10 EKG14713.1 - 2.3e-57 192.5 0.0 3.2e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EKG14713.1 - 2.8e-07 30.0 0.0 4.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG14713.1 - 4.3e-07 29.8 0.0 8.3e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG14713.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDOST_48kD PF03345.9 EKG14714.1 - 2.2e-156 520.6 0.0 2.5e-156 520.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2476 PF10630.4 EKG14714.1 - 0.25 11.2 0.8 0.44 10.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) RNase_H2-Ydr279 PF09468.5 EKG14716.1 - 0.2 10.8 1.3 0.3 10.2 0.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RXT2_N PF08595.6 EKG14716.1 - 0.21 11.3 11.6 1.8 8.3 0.3 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal BTV_NS2 PF04514.7 EKG14716.1 - 0.26 10.1 14.0 0.29 9.9 4.1 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Nucleo_P87 PF07267.6 EKG14716.1 - 1.8 7.1 7.1 0.86 8.2 1.5 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 S-antigen PF05756.6 EKG14716.1 - 2.9 7.9 10.1 2.7 8.0 3.5 2.3 2 0 0 2 2 2 0 S-antigen protein CobT PF06213.7 EKG14716.1 - 3.7 6.5 15.2 1.3 8.0 2.7 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EKG14716.1 - 9.7 4.5 15.7 6.7 5.0 0.4 2.1 2 0 0 2 2 2 0 Daxx Family Myosin_head PF00063.16 EKG14717.1 - 1.4e-249 829.8 0.0 1.4e-249 829.8 0.0 2.4 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EKG14717.1 - 2.2e-26 91.9 287.1 6.7e-22 77.0 75.4 5.3 2 2 1 3 3 3 2 Myosin tail Myosin_N PF02736.14 EKG14717.1 - 0.00015 21.3 0.0 0.00045 19.8 0.0 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EKG14717.1 - 0.052 13.3 0.5 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Reo_sigmaC PF04582.7 EKG14717.1 - 0.081 12.0 89.2 0.11 11.6 4.7 10.0 5 3 6 11 11 11 0 Reovirus sigma C capsid protein zf-C3H1 PF10650.4 EKG14718.1 - 1.8e-07 30.5 0.1 3.1e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain adh_short PF00106.20 EKG14719.1 - 5.3e-15 55.7 0.0 1.9e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EKG14719.1 - 2e-05 24.4 0.0 0.0036 17.1 0.0 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG14719.1 - 0.024 14.3 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 KR domain WD40 PF00400.27 EKG14720.1 - 5.3e-62 203.6 13.8 9e-10 38.0 0.5 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EKG14720.1 - 1.2e-13 50.5 0.2 2.6e-13 49.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG14720.1 - 9.3e-12 44.2 0.1 2.5e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EKG14720.1 - 4.6e-09 34.9 7.3 0.25 9.4 0.0 5.7 3 3 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EKG14720.1 - 0.0087 14.8 0.1 0.036 12.8 0.1 1.9 1 1 1 2 2 2 1 Nup133 N terminal like APG17 PF04108.7 EKG14721.1 - 4.5e-90 302.4 0.0 1.6e-59 201.7 0.0 2.0 2 0 0 2 2 2 2 Autophagy protein Apg17 RIO1 PF01163.17 EKG14722.1 - 7.4e-69 230.8 0.8 9.7e-69 230.5 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EKG14722.1 - 1.5e-06 28.1 0.8 0.028 14.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EKG14722.1 - 0.0086 15.1 0.2 0.26 10.3 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SNase PF00565.12 EKG14723.1 - 1.4e-71 237.6 0.8 1.7e-25 89.3 0.0 5.9 6 1 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EKG14723.1 - 1.9e-23 82.5 0.0 6.1e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EKG14723.1 - 3.3e-07 29.6 0.0 7.7e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Sod_Cu PF00080.15 EKG14724.1 - 1.7e-44 151.4 6.1 2e-44 151.1 4.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Transaldolase PF00923.14 EKG14725.1 - 1.4e-95 319.7 1.0 1.6e-95 319.5 0.7 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 EKG14725.1 - 0.014 14.6 0.0 0.024 13.9 0.0 1.4 1 1 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus RTA1 PF04479.8 EKG14726.1 - 6.7e-50 169.6 0.5 1.1e-49 169.0 0.3 1.2 1 0 0 1 1 1 1 RTA1 like protein TMEM223 PF14640.1 EKG14726.1 - 0.0084 16.0 0.2 2.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Transmembrane protein 223 Glyco_hydro_43 PF04616.9 EKG14728.1 - 1.4e-46 158.9 8.9 1.6e-46 158.7 6.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 NmrA PF05368.8 EKG14729.1 - 8.4e-11 41.5 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG14729.1 - 4.6e-08 33.2 0.0 7.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EKG14729.1 - 6.3e-05 22.0 0.0 9.6e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EKG14729.1 - 0.00056 19.4 0.3 0.0035 16.8 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EKG14729.1 - 0.039 13.6 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 KR domain Phi-29_GP4 PF05464.6 EKG14729.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) p450 PF00067.17 EKG14730.1 - 1.5e-53 181.9 0.0 1.9e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG14731.1 - 2.5e-25 88.9 0.0 3.7e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EKG14733.1 - 5.5e-08 32.0 0.3 9.9e-08 31.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain REV PF00424.13 EKG14733.1 - 0.48 10.3 2.9 1.4 8.9 0.5 2.5 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Abhydrolase_6 PF12697.2 EKG14735.1 - 4.2e-27 95.5 2.3 9.3e-27 94.3 1.6 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG14735.1 - 2.1e-10 40.5 0.0 3.6e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG14735.1 - 1.3e-09 37.9 1.6 2.1e-09 37.3 1.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EKG14735.1 - 5.4e-07 29.3 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EKG14735.1 - 0.00016 21.1 0.1 0.00031 20.2 0.0 1.5 1 1 0 1 1 1 1 Putative esterase eIF-5a PF01287.15 EKG14736.1 - 2.1e-07 30.7 0.1 4.2e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DIOX_N PF14226.1 EKG14737.1 - 1.1e-11 45.3 0.0 1.3e-10 41.8 0.0 2.3 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG14737.1 - 2.8e-10 40.3 0.0 1.5e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SNO PF01174.14 EKG14738.1 - 1.8e-55 187.5 0.0 7.9e-44 149.5 0.0 2.1 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EKG14738.1 - 7.8e-11 41.8 0.0 5.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EKG14738.1 - 1.4e-05 24.6 0.0 6.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EKG14738.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EKG14738.1 - 0.0011 18.2 0.1 0.0022 17.3 0.1 1.4 1 0 0 1 1 1 1 Putative amidotransferase BMFP PF04380.8 EKG14738.1 - 0.1 12.7 0.3 0.63 10.2 0.3 2.1 2 0 0 2 2 2 0 Membrane fusogenic activity RRM_1 PF00076.17 EKG14739.1 - 1.5e-15 56.5 0.0 2.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG14739.1 - 1.3e-11 44.3 0.0 1.9e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG14739.1 - 1.5e-08 34.3 0.1 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EKG14740.1 - 0.078 12.9 0.1 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Gp-FAR-1 PF05823.7 EKG14740.1 - 0.18 11.7 7.6 0.95 9.4 5.3 2.2 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF948 PF06103.6 EKG14740.1 - 2.4 8.0 8.8 6 6.7 0.2 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Hormone_1 PF00103.15 EKG14740.1 - 3 7.1 7.0 2.1 7.6 0.4 3.0 2 2 1 3 3 3 0 Somatotropin hormone family ERM PF00769.14 EKG14740.1 - 5 6.5 25.2 0.55 9.7 13.9 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family SRR1 PF07985.7 EKG14742.1 - 0.0055 16.6 0.0 0.0083 16.0 0.0 1.3 1 0 0 1 1 1 1 SRR1 Cyto_ox_2 PF02322.10 EKG14743.1 - 0.0098 15.0 2.8 0.011 14.8 2.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase subunit II YjgP_YjgQ PF03739.9 EKG14743.1 - 0.024 13.4 1.8 0.028 13.1 1.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family VIT1 PF01988.14 EKG14743.1 - 0.026 14.0 2.9 0.031 13.7 2.0 1.1 1 0 0 1 1 1 0 VIT family DUF2207 PF09972.4 EKG14743.1 - 0.2 10.2 2.3 0.23 9.9 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF588 PF04535.7 EKG14743.1 - 0.24 10.9 7.8 0.51 9.8 5.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF588) ABC2_membrane_2 PF12679.2 EKG14743.1 - 0.47 9.2 6.3 0.63 8.8 4.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 EKG14743.1 - 0.57 9.3 11.2 0.73 8.9 7.8 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4231 PF14015.1 EKG14743.1 - 1.1 9.3 6.1 1.1 9.3 3.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF1772 PF08592.6 EKG14743.1 - 2 8.1 6.8 3.9 7.2 4.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) IncA PF04156.9 EKG14743.1 - 4 6.9 11.4 5.2 6.6 7.9 1.3 1 0 0 1 1 1 0 IncA protein ERGIC_N PF13850.1 EKG14743.1 - 9.6 6.2 6.4 4.7 7.2 0.3 2.2 1 1 1 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SH3_3 PF08239.6 EKG14744.1 - 0.041 14.0 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain DUF1469 PF07332.6 EKG14745.1 - 0.025 14.3 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3392 PF11872.3 EKG14745.1 - 0.058 13.3 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) RGCC PF15151.1 EKG14745.1 - 0.066 13.6 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 Response gene to complement 32 protein family DUF2404 PF10296.4 EKG14746.1 - 0.00021 21.3 0.0 0.0009 19.3 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) TRAM_LAG1_CLN8 PF03798.11 EKG14747.1 - 1.1e-43 149.1 12.8 1.1e-43 149.1 8.9 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EKG14747.1 - 8.5e-21 73.2 0.1 2.4e-20 71.8 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein Kelch_6 PF13964.1 EKG14748.1 - 4.7e-06 26.5 5.4 2.9 8.2 0.1 5.9 5 1 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 EKG14748.1 - 0.00021 20.9 0.4 4.2 7.2 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Herpes_gE PF02480.11 EKG14748.1 - 0.0032 15.8 0.1 0.0046 15.2 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EKG14748.1 - 0.008 15.0 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Beta-APP PF03494.8 EKG14748.1 - 0.015 14.7 3.3 0.042 13.3 2.3 1.7 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Protocadherin PF08374.6 EKG14748.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Syndecan PF01034.15 EKG14748.1 - 0.028 14.0 0.2 0.064 12.9 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Yip1 PF04893.12 EKG14748.1 - 0.031 13.7 0.2 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 Yip1 domain Mid2 PF04478.7 EKG14748.1 - 0.057 12.8 0.3 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Rifin_STEVOR PF02009.11 EKG14748.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family SKG6 PF08693.5 EKG14748.1 - 0.2 10.9 3.8 0.069 12.4 0.6 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EKG14748.1 - 0.27 10.8 1.0 0.47 10.0 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Kelch_4 PF13418.1 EKG14748.1 - 0.56 10.0 18.8 0.71 9.6 0.2 5.8 6 2 0 6 6 6 0 Galactose oxidase, central domain Glyco_hydro_75 PF07335.6 EKG14749.1 - 6.6e-48 162.5 0.1 8e-48 162.2 0.0 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 p450 PF00067.17 EKG14750.1 - 6.4e-56 189.7 0.0 7.6e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 EKG14751.1 - 3.2e-64 216.1 5.8 1.1e-63 214.3 4.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG14751.1 - 6e-46 156.2 7.9 6e-46 156.2 5.5 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG14751.1 - 4.2e-33 115.5 0.1 1.1e-32 114.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG14751.1 - 4.7e-22 77.7 0.0 9.5e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EKG14751.1 - 1.6e-16 61.0 0.0 5.1e-16 59.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG14751.1 - 9.9e-10 38.4 0.6 8.7e-07 28.7 0.5 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EKG14751.1 - 0.0037 17.4 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EKG14751.1 - 0.019 14.8 0.0 0.08 12.8 0.0 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Response_reg PF00072.19 EKG14752.1 - 3.3e-21 75.3 0.2 7.5e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EKG14752.1 - 3.4e-20 71.8 0.0 5.7e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EKG14752.1 - 1.3e-05 25.0 0.0 4.4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain F-box-like_2 PF13013.1 EKG14753.1 - 0.0015 18.1 0.0 0.0044 16.7 0.0 1.9 1 1 0 1 1 1 1 F-box-like domain CBM_2 PF00553.14 EKG14754.1 - 0.058 13.4 0.1 0.084 12.9 0.1 1.2 1 0 0 1 1 1 0 Cellulose binding domain Nucleo_P87 PF07267.6 EKG14755.1 - 0.09 11.4 0.5 0.096 11.3 0.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ADK PF00406.17 EKG14756.1 - 5e-47 159.5 0.0 6.2e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EKG14756.1 - 3.3e-11 43.5 0.0 4.8e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EKG14756.1 - 8.2e-07 28.5 0.3 0.0024 17.2 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 EKG14756.1 - 1.7e-06 28.8 0.0 2.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG14756.1 - 1.7e-05 24.7 0.0 4.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EKG14756.1 - 0.015 14.3 0.0 0.031 13.3 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EKG14756.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.21 EKG14757.1 - 4.3e-45 153.3 0.3 7.9e-31 106.8 0.0 2.5 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EKG14757.1 - 3.3e-12 45.4 0.0 3.3e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature His_Phos_1 PF00300.17 EKG14758.1 - 6e-18 65.4 0.0 9.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SIS PF01380.17 EKG14759.1 - 6e-55 184.3 0.0 4.4e-30 103.9 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EKG14759.1 - 3.5e-20 72.0 0.0 1.3e-17 63.6 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EKG14759.1 - 3.8e-19 68.9 0.0 8.3e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EKG14759.1 - 2.5e-11 43.3 0.0 5.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EKG14759.1 - 3.9e-06 25.7 0.0 7.5e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EKG14759.1 - 0.0014 18.3 0.0 0.29 10.8 0.0 2.7 2 0 0 2 2 2 1 SIS domain Phage_attach PF05354.6 EKG14759.1 - 0.067 12.7 0.0 10 5.7 0.0 2.5 1 1 1 2 2 2 0 Phage Head-Tail Attachment DMRL_synthase PF00885.14 EKG14760.1 - 6.7e-43 145.8 0.2 4.4e-23 81.5 0.1 2.1 1 1 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase N-SET PF11764.3 EKG14761.1 - 3.9e-40 137.4 0.6 3.9e-40 137.4 0.4 3.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EKG14761.1 - 2.2e-26 90.9 0.3 4.4e-26 89.9 0.2 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EKG14761.1 - 8.4e-24 84.7 0.1 8.4e-24 84.7 0.1 3.5 3 3 0 3 3 3 1 SET domain RRM_1 PF00076.17 EKG14761.1 - 4.7e-06 26.1 0.0 1.1e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG14761.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 EKG14762.1 - 3.9e-15 56.0 0.2 1.6e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain B1 PF02246.10 EKG14762.1 - 0.0079 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein L b1 domain HET PF06985.6 EKG14763.1 - 5e-25 88.2 0.0 8.1e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Neur_chan_memb PF02932.11 EKG14764.1 - 3.6 7.3 6.2 12 5.7 0.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Proteasome PF00227.21 EKG14765.1 - 4.8e-40 136.8 0.0 5.8e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 EKG14767.1 - 2.8e-40 137.5 0.0 8.6e-39 132.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG14767.1 - 1.2e-25 89.2 0.2 2.9e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2984 PF11203.3 EKG14767.1 - 0.046 13.8 1.1 0.11 12.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) p450 PF00067.17 EKG14768.1 - 3.9e-14 52.0 0.0 6e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.16 EKG14769.1 - 4.4e-110 368.2 40.5 5.3e-110 368.0 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG14769.1 - 2.7e-26 92.0 43.9 3.4e-26 91.7 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease LSM PF01423.17 EKG14771.1 - 4.3e-21 74.2 0.2 4.8e-21 74.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain DUF3074 PF11274.3 EKG14773.1 - 2.1e-41 141.6 0.0 2.6e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) HMG_box PF00505.14 EKG14775.1 - 6.8e-13 48.6 0.6 6.8e-13 48.6 0.4 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box SAM_1 PF00536.25 EKG14775.1 - 6.1e-11 42.3 0.1 6.1e-11 42.3 0.1 1.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 EKG14775.1 - 2.4e-10 40.6 1.5 2.4e-10 40.6 1.1 2.2 2 0 0 2 2 2 1 HMG-box domain SAM_2 PF07647.12 EKG14775.1 - 2.9e-05 23.7 0.0 6.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DltD_C PF04914.7 EKG14775.1 - 0.019 14.8 0.5 0.034 14.0 0.4 1.4 1 0 0 1 1 1 0 DltD C-terminal region NCD1 PF04904.8 EKG14775.1 - 0.12 12.1 0.1 0.69 9.6 0.0 2.2 2 1 0 2 2 2 0 NAB conserved region 1 (NCD1) Tox-WTIP PF15654.1 EKG14776.1 - 0.081 12.5 0.5 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif p450 PF00067.17 EKG14777.1 - 3.4e-15 55.5 0.0 7e-15 54.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 MCM PF00493.18 EKG14779.1 - 3.9e-132 440.0 0.0 6.9e-132 439.2 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKG14779.1 - 5.9e-28 97.7 0.1 2e-27 96.0 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKG14779.1 - 3.4e-07 29.6 0.0 2.7e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKG14779.1 - 3e-06 27.0 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EKG14779.1 - 0.011 16.1 0.9 0.033 14.5 0.3 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKG14779.1 - 0.03 13.9 0.1 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKG14779.1 - 0.09 12.2 0.0 0.88 9.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.1 EKG14779.1 - 2 8.3 6.4 21 5.0 0.1 3.4 3 1 0 4 4 4 0 AAA ATPase domain AAA PF00004.24 EKG14780.1 - 2.9e-53 179.5 0.0 2e-43 147.7 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EKG14780.1 - 1.4e-17 63.5 0.0 2.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EKG14780.1 - 1e-07 32.1 17.1 0.00041 20.3 1.2 5.4 4 2 0 5 5 4 2 AAA ATPase domain AAA_2 PF07724.9 EKG14780.1 - 5e-07 29.7 0.0 0.084 12.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EKG14780.1 - 1.2e-06 28.2 0.9 0.0049 16.5 0.1 3.6 3 1 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EKG14780.1 - 3.3e-06 27.9 0.0 0.096 13.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKG14780.1 - 4e-06 27.0 0.8 0.059 13.5 0.0 3.6 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EKG14780.1 - 5e-06 25.7 0.0 0.01 14.8 0.0 3.0 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EKG14780.1 - 9.2e-06 25.3 0.0 0.029 14.1 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 EKG14780.1 - 4.7e-05 23.1 0.1 0.28 10.8 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EKG14780.1 - 0.00014 21.7 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKG14780.1 - 0.0002 20.8 7.3 1.8 7.9 0.1 5.0 3 2 2 5 5 5 1 AAA domain Sigma54_activ_2 PF14532.1 EKG14780.1 - 0.00063 19.8 0.0 0.37 10.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 EKG14780.1 - 0.00071 19.2 0.3 0.02 14.5 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EKG14780.1 - 0.0024 16.9 5.0 0.44 9.6 0.0 3.0 3 0 0 3 3 2 2 Zeta toxin AAA_18 PF13238.1 EKG14780.1 - 0.0034 17.6 4.6 0.2 11.9 0.1 3.2 3 1 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EKG14780.1 - 0.0075 16.1 5.7 0.32 10.8 0.0 3.9 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EKG14780.1 - 0.0086 16.2 0.0 3.8 7.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 EKG14780.1 - 0.0087 15.4 8.7 0.075 12.4 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein NB-ARC PF00931.17 EKG14780.1 - 0.017 14.0 0.0 5.2 5.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 EKG14780.1 - 0.022 13.4 0.1 0.82 8.3 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Sigma54_activat PF00158.21 EKG14780.1 - 0.024 14.1 0.0 2.4 7.6 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Vps4_C PF09336.5 EKG14780.1 - 0.033 14.0 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain KaiC PF06745.8 EKG14780.1 - 0.056 12.5 0.1 9.8 5.2 0.0 2.3 2 0 0 2 2 2 0 KaiC CMV_1a PF12467.3 EKG14780.1 - 0.061 13.6 6.5 0.12 12.7 4.5 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF1675 PF07897.6 EKG14780.1 - 0.31 10.8 10.0 0.77 9.5 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) AAA_28 PF13521.1 EKG14780.1 - 0.42 10.5 10.2 0.79 9.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.22 EKG14780.1 - 0.46 10.7 6.9 9.7 6.4 0.1 3.5 3 0 0 3 3 2 0 ABC transporter Mg_chelatase PF01078.16 EKG14780.1 - 0.56 9.3 6.2 0.62 9.1 0.0 2.8 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.9 EKG14780.1 - 0.96 8.3 6.0 1.9 7.3 0.0 3.2 2 1 1 3 3 3 0 KAP family P-loop domain PGA2 PF07543.7 EKG14780.1 - 1.4 8.7 8.3 3.9 7.2 5.8 1.8 1 0 0 1 1 1 0 Protein trafficking PGA2 RAB3GAP2_N PF14655.1 EKG14780.1 - 3.6 6.4 8.8 6 5.7 6.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SKI PF01202.17 EKG14780.1 - 3.7 7.3 8.0 4.4 7.1 0.0 3.4 4 0 0 4 4 3 0 Shikimate kinase APC_CDC26 PF10471.4 EKG14780.1 - 4.5 8.0 19.8 16 6.3 13.7 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Hid1 PF12722.2 EKG14780.1 - 4.6 4.7 9.1 6.4 4.3 6.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Activator_LAG-3 PF11498.3 EKG14780.1 - 9.1 4.8 26.0 14 4.2 18.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 MPC PF03650.8 EKG14781.1 - 5e-35 120.0 0.0 6.1e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 EKG14782.1 - 4.2e-16 58.2 0.0 5.1e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EKG14783.1 - 7.7e-23 80.0 0.0 1.1e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EKG14783.1 - 5.6e-21 74.0 0.1 1.6e-20 72.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Sulfatase PF00884.18 EKG14784.1 - 1.9e-25 89.6 0.0 2.5e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EKG14784.1 - 0.01 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EKG14785.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF1634 PF07843.6 EKG14785.1 - 0.12 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) Methyltransf_16 PF10294.4 EKG14787.1 - 5.4e-51 172.4 0.0 7.2e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EKG14787.1 - 3.4e-06 27.6 0.0 6.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG14787.1 - 6.2e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EKG14787.1 - 7.1e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG14787.1 - 0.0002 21.1 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG14787.1 - 0.00064 19.7 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG14787.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG14787.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EKG14787.1 - 0.024 13.7 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PCMT PF01135.14 EKG14787.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Orn_Arg_deC_N PF02784.11 EKG14788.1 - 3.6e-78 262.2 0.0 5.2e-78 261.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EKG14788.1 - 3.9e-32 110.3 0.1 6.7e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EKG14788.1 - 0.0026 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel APG5 PF04106.7 EKG14789.1 - 1.1e-49 168.6 0.0 1.4e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 WD40 PF00400.27 EKG14791.1 - 3.7e-32 109.0 15.8 1.1e-09 37.8 0.6 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat TSNR_N PF04705.7 EKG14791.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus DUF2693 PF10902.3 EKG14791.1 - 0.25 11.2 1.5 0.72 9.8 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) UAF_Rrn10 PF05234.6 EKG14792.1 - 0.00092 19.2 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Sugar_tr PF00083.19 EKG14793.1 - 7.1e-89 298.4 25.4 8.5e-89 298.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG14793.1 - 1.2e-31 109.7 39.8 2.1e-29 102.3 13.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG14793.1 - 5.9e-07 28.0 2.2 5.9e-07 28.0 1.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EKG14793.1 - 1.4e-06 27.0 30.7 1.5e-05 23.6 4.2 3.2 2 2 0 3 3 3 2 MFS/sugar transport protein CCSMST1 PF15013.1 EKG14793.1 - 1.9 8.4 3.7 1.5 8.8 0.4 2.4 2 0 0 2 2 2 0 CCSMST1 family HAD PF12710.2 EKG14794.1 - 4.2e-10 40.1 0.0 6e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG14794.1 - 0.015 15.7 0.1 0.073 13.4 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Fer2_3 PF13085.1 EKG14795.1 - 2e-31 108.0 0.0 3.3e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EKG14795.1 - 2.9e-09 37.1 7.8 2.9e-09 37.1 5.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKG14795.1 - 9e-09 35.2 5.4 9e-09 35.2 3.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKG14795.1 - 0.00023 20.8 5.2 0.00023 20.8 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EKG14795.1 - 0.00032 21.0 2.7 0.00032 21.0 1.9 2.8 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EKG14795.1 - 0.0005 20.2 4.9 0.027 14.7 0.6 3.1 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer2 PF00111.22 EKG14795.1 - 0.0069 16.1 0.3 0.0069 16.1 0.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EKG14795.1 - 0.025 14.9 6.3 0.025 14.9 4.3 2.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 EKG14795.1 - 0.42 11.0 3.3 0.56 10.6 0.4 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 EKG14795.1 - 1.2 9.7 5.2 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF3602 PF12223.3 EKG14796.1 - 5.9e-18 65.0 3.0 8.4e-18 64.5 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) COesterase PF00135.23 EKG14797.1 - 3.4e-37 128.3 0.0 3.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG14797.1 - 0.00097 18.7 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG14797.1 - 0.057 12.6 0.4 0.095 11.9 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family eIF2A PF08662.6 EKG14798.1 - 4.1e-41 140.8 1.1 8e-39 133.3 0.1 3.8 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EKG14798.1 - 3.4e-07 30.1 0.0 8.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG14798.1 - 5.8e-05 22.6 0.1 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EKG14798.1 - 0.00012 21.8 0.3 0.028 14.3 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_5 PF13893.1 EKG14798.1 - 0.00031 20.5 0.0 0.00084 19.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vir_act_alpha_C PF10400.4 EKG14798.1 - 0.024 14.9 3.8 0.064 13.6 2.6 1.7 1 0 0 1 1 1 0 Virulence activator alpha C-term IKI3 PF04762.7 EKG14798.1 - 0.028 12.2 0.0 0.093 10.5 0.0 1.7 2 0 0 2 2 2 0 IKI3 family DUF2203 PF09969.4 EKG14798.1 - 0.029 14.6 1.4 0.33 11.1 0.6 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2497 PF10691.4 EKG14798.1 - 4.1 7.4 7.3 0.23 11.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Ilm1 PF10311.4 EKG14799.1 - 7.9e-46 155.5 0.3 9.2e-46 155.3 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Peptidase_M19 PF01244.16 EKG14800.1 - 7.8e-94 314.1 0.0 9.2e-94 313.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MutS_V PF00488.16 EKG14801.1 - 1.3e-84 283.2 0.0 2.3e-84 282.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EKG14801.1 - 9.4e-37 126.7 1.3 1.6e-36 126.0 0.4 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EKG14801.1 - 7.8e-27 93.5 0.0 2.1e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EKG14801.1 - 5.9e-11 42.3 1.7 1e-10 41.6 0.1 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EKG14801.1 - 6.4e-09 35.9 0.0 2.1e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 MutS domain II Glyco_transf_34 PF05637.7 EKG14801.1 - 0.034 13.6 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family AAA_16 PF13191.1 EKG14801.1 - 0.037 13.9 0.8 0.37 10.7 0.1 2.9 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_C48 PF02902.14 EKG14802.1 - 1.1e-16 61.1 0.0 4.6e-16 59.0 0.0 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain hDGE_amylase PF14701.1 EKG14803.1 - 9.6e-182 604.5 0.0 1.2e-181 604.2 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EKG14803.1 - 5.1e-113 377.5 0.0 8.5e-113 376.8 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EKG14803.1 - 1.9e-85 286.1 0.0 3.1e-85 285.4 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EKG14803.1 - 2.9e-24 84.7 0.0 6.5e-24 83.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EKG14803.1 - 2.5e-06 27.1 0.8 2.1e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain RhoGAP PF00620.22 EKG14804.1 - 3.1e-29 101.5 0.0 5.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Pam17 PF08566.5 EKG14805.1 - 6.2e-63 211.5 0.0 9.2e-63 211.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Myco_19_kDa PF05481.7 EKG14805.1 - 4.3 7.1 9.5 0.65 9.8 3.4 2.0 1 1 1 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen CMAS PF02353.15 EKG14806.1 - 1.9e-61 207.5 0.0 2.4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EKG14806.1 - 1.3e-12 47.7 0.0 2.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG14806.1 - 3.7e-09 36.9 0.0 7.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG14806.1 - 9.2e-05 22.7 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG14806.1 - 0.00068 19.6 0.0 0.0018 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG14806.1 - 0.0016 18.9 0.1 0.0054 17.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG14806.1 - 0.0032 16.8 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EKG14806.1 - 0.0049 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG14806.1 - 0.0052 16.3 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKG14806.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 EKG14806.1 - 0.043 13.1 0.0 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.7 EKG14806.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Adaptin_N PF01602.15 EKG14807.1 - 8.5e-84 281.7 0.0 1.4e-82 277.6 0.0 2.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EKG14807.1 - 0.018 14.8 1.3 6.4 6.5 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EKG14807.1 - 0.4 11.2 4.7 59 4.3 0.0 5.2 4 1 1 5 5 5 0 HEAT-like repeat TPR_19 PF14559.1 EKG14808.1 - 5.9e-09 36.1 2.8 3.3e-05 24.1 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG14808.1 - 1.1e-06 28.6 5.5 0.089 13.4 0.1 4.8 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG14808.1 - 3.7e-05 23.2 0.7 0.0013 18.3 0.0 3.3 3 1 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 EKG14808.1 - 0.00025 20.7 0.0 0.14 12.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG14808.1 - 0.00075 20.1 5.4 0.082 13.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKG14808.1 - 0.0014 18.5 0.5 2.3 8.2 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKG14808.1 - 0.0023 17.5 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKG14808.1 - 0.0038 17.2 0.1 0.19 12.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.5 EKG14808.1 - 0.0056 15.4 0.1 0.0081 14.9 0.1 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) HrpJ PF07201.6 EKG14808.1 - 0.042 13.8 0.4 0.17 11.8 0.1 1.9 1 1 1 2 2 2 0 HrpJ-like domain TPR_9 PF13371.1 EKG14808.1 - 0.09 12.6 1.4 1.2 8.9 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EKG14808.1 - 0.17 12.0 2.5 0.96 9.6 0.1 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat HSA PF07529.8 EKG14809.1 - 1.8e-16 59.7 3.4 1.8e-16 59.7 2.4 4.7 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.1 EKG14809.1 - 2.7e-10 40.1 0.5 2.7e-10 40.1 0.4 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG14809.1 - 0.0019 18.2 0.6 0.0051 16.8 0.4 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 EKG14810.1 - 1.9e-16 59.2 0.0 0.00095 18.9 0.0 6.0 5 1 0 5 5 5 4 WD domain, G-beta repeat SUKH_5 PF14567.1 EKG14810.1 - 0.078 12.4 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall p450 PF00067.17 EKG14811.1 - 1.2e-43 149.3 0.0 1.4e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aa_trans PF01490.13 EKG14812.1 - 3.2e-88 295.9 33.7 3.8e-88 295.7 23.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 EKG14813.1 - 2.9e-57 194.1 34.9 3.6e-57 193.7 24.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG14813.1 - 3.6e-15 55.4 41.9 5.7e-15 54.7 29.0 1.2 1 0 0 1 1 1 1 Amino acid permease CDC45 PF02724.9 EKG14813.1 - 9.3 4.1 6.1 15 3.4 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CFEM PF05730.6 EKG14814.1 - 0.22 11.3 6.9 0.73 9.7 4.8 2.0 1 1 0 1 1 1 0 CFEM domain EB PF01683.13 EKG14814.1 - 1.2 9.3 5.0 6.7 6.8 1.7 2.4 2 1 0 2 2 2 0 EB module ADH_zinc_N PF00107.21 EKG14816.1 - 2.4e-17 62.6 0.4 6.5e-17 61.2 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG14816.1 - 3.4e-15 57.0 0.9 5.9e-15 56.2 0.1 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG14816.1 - 9.7e-11 41.4 0.0 1.1e-07 31.5 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EKG14816.1 - 0.00075 19.0 0.1 0.0012 18.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 EKG14816.1 - 0.011 16.2 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EKG14816.1 - 0.032 14.1 0.3 0.085 12.7 0.2 1.7 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EKG14816.1 - 0.055 13.4 0.1 0.098 12.6 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding NMO PF03060.10 EKG14817.1 - 3.7e-40 138.0 6.5 1e-33 116.8 3.8 2.0 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EKG14817.1 - 2.2e-05 23.4 2.2 3e-05 23.0 1.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EKG14817.1 - 0.0003 19.8 0.3 0.00051 19.0 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EKG14817.1 - 0.0014 17.5 0.9 0.0049 15.7 0.9 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain AIG2_2 PF13772.1 EKG14818.1 - 6.4e-07 29.4 0.1 2e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 AIG2-like family SCF PF02404.10 EKG14820.1 - 0.063 12.4 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Stem cell factor RabGAP-TBC PF00566.13 EKG14821.1 - 2.9e-31 108.6 0.0 5.6e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Telomerase_RBD PF12009.3 EKG14822.1 - 8.5e-42 142.2 1.5 2e-41 141.1 0.7 1.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EKG14822.1 - 2.9e-14 52.9 0.0 1.7e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 EKG14823.1 - 3.7e-35 121.4 0.0 6.9e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EKG14823.1 - 6.6e-13 48.7 0.3 1.7e-12 47.3 0.2 1.7 1 0 0 1 1 1 1 BAR domain Prenyltrans PF00432.16 EKG14824.1 - 1.6e-55 184.2 8.1 1.6e-11 43.5 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKG14824.1 - 2.7e-32 111.5 0.0 1.2e-11 45.0 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EKG14824.1 - 7.9e-12 45.1 0.0 0.00093 19.1 0.0 3.5 1 1 2 3 3 3 3 Prenyltransferase-like HisG PF01634.13 EKG14827.1 - 1.3e-52 177.6 0.2 2e-52 177.0 0.2 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EKG14827.1 - 1.6e-29 101.6 0.1 3.5e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EKG14827.1 - 0.019 14.5 0.1 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 NMT1/THI5 like Ribosomal_S28e PF01200.13 EKG14828.1 - 1e-32 111.6 2.9 1.1e-32 111.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e SNF2_N PF00176.18 EKG14829.1 - 4.7e-70 235.7 0.0 7e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EKG14829.1 - 2.5e-09 36.8 9.8 5.3e-09 35.7 6.8 1.6 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 EKG14829.1 - 2.9e-09 36.6 0.0 7.7e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EKG14829.1 - 6.7e-08 32.4 10.9 6.7e-08 32.4 7.6 2.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG14829.1 - 2.1e-06 27.7 5.3 1.1e-05 25.3 3.7 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKG14829.1 - 2.3e-06 27.1 10.5 5.4e-06 25.9 7.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG14829.1 - 5e-06 26.0 7.2 5e-06 26.0 5.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG14829.1 - 0.00016 21.3 8.4 0.00032 20.3 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EKG14829.1 - 0.001 18.9 10.5 0.0019 18.0 7.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EKG14829.1 - 0.0049 16.3 5.5 0.011 15.1 3.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ResIII PF04851.10 EKG14829.1 - 0.037 13.8 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-Apc11 PF12861.2 EKG14829.1 - 0.04 13.7 2.4 0.1 12.4 1.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EKG14829.1 - 0.074 12.7 5.9 0.17 11.6 4.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EKG14829.1 - 3.8 7.0 11.1 3.2 7.3 3.7 2.9 2 1 1 3 3 3 0 P-11 zinc finger zf-RING_4 PF14570.1 EKG14829.1 - 7.1 6.2 7.5 14 5.3 5.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3543 PF12063.3 EKG14830.1 - 1.5e-84 282.9 0.0 2.3e-84 282.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EKG14830.1 - 4.5e-59 199.7 0.0 9e-59 198.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG14830.1 - 2.1e-40 138.4 0.0 3.7e-40 137.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.11 EKG14831.1 - 6.1e-33 113.9 18.2 6.1e-33 113.9 12.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DEAD PF00270.24 EKG14832.1 - 2.1e-46 157.5 0.0 5.3e-45 152.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG14832.1 - 1.5e-28 98.4 0.0 3.1e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EKG14832.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EKG14832.1 - 0.035 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pro_isomerase PF00160.16 EKG14833.1 - 5.4e-48 163.1 1.1 7.3e-48 162.6 0.7 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 EKG14834.1 - 1.5e-24 86.5 0.6 1.6e-24 86.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EKG14834.1 - 0.016 13.7 0.0 0.021 13.4 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Helicase_C PF00271.26 EKG14839.1 - 4.9e-20 71.1 0.1 1.3e-17 63.4 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EKG14839.1 - 3.5e-18 65.6 0.0 8.3e-18 64.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EKG14839.1 - 0.0047 15.7 0.0 0.0073 15.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3391 PF11871.3 EKG14839.1 - 0.062 13.5 0.0 38 4.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Helicase_C_2 PF13307.1 EKG14839.1 - 0.094 12.6 0.0 0.34 10.8 0.0 2.0 1 1 1 2 2 2 0 Helicase C-terminal domain Zip PF02535.17 EKG14840.1 - 4.8e-46 157.2 0.2 6.1e-46 156.8 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter ADH_zinc_N PF00107.21 EKG14841.1 - 4.6e-30 103.8 0.4 7.1e-30 103.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG14841.1 - 4.3e-22 77.9 1.1 8.7e-22 76.9 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EKG14841.1 - 1.8e-07 32.1 0.1 3.9e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer2_3 PF13085.1 EKG14841.1 - 0.089 12.6 0.1 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain AIRC PF00731.15 EKG14841.1 - 0.3 10.3 2.2 0.26 10.5 0.3 1.7 1 1 1 2 2 2 0 AIR carboxylase FAD_binding_4 PF01565.18 EKG14842.1 - 6.1e-21 74.3 0.2 1.1e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG14842.1 - 3.5e-11 42.8 0.0 9.6e-11 41.4 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Peptidase_S10 PF00450.17 EKG14843.1 - 3.9e-108 362.2 1.1 4.7e-108 362.0 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carb_anhydrase PF00194.16 EKG14844.1 - 2.4e-21 75.8 0.2 4.3e-21 75.0 0.2 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Methyltransf_21 PF05050.7 EKG14844.1 - 0.082 12.8 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain FAD_binding_3 PF01494.14 EKG14845.1 - 4.8e-10 39.0 0.2 2.8e-09 36.5 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EKG14845.1 - 0.026 13.6 0.0 0.094 11.7 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EKG14845.1 - 0.11 11.3 0.0 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_4 PF07993.7 EKG14846.1 - 2.7e-32 111.6 0.0 4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EKG14846.1 - 3.2e-27 94.9 0.0 7.7e-26 90.4 0.0 2.6 2 1 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EKG14846.1 - 3.1e-08 33.7 0.1 6e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EKG14846.1 - 5.2e-05 22.8 0.0 8.8e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EKG14846.1 - 0.00055 19.8 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase COesterase PF00135.23 EKG14847.1 - 5.9e-73 246.3 0.0 7.3e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG14847.1 - 7.5e-06 25.6 2.7 4.2e-05 23.2 1.9 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 EKG14848.1 - 1.5e-14 54.1 0.3 4.1e-12 46.1 0.3 2.1 1 1 1 2 2 2 2 Cutinase PE-PPE PF08237.6 EKG14848.1 - 0.0055 16.1 0.1 0.0073 15.7 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Lipase PF00151.14 EKG14848.1 - 0.059 12.5 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Lipase DUF3431 PF11913.3 EKG14849.1 - 6e-14 52.0 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Fanconi_A PF03511.9 EKG14849.1 - 0.17 11.6 1.7 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Fanconi anaemia group A protein BTB_2 PF02214.17 EKG14850.1 - 4.6e-09 36.3 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EKG14850.1 - 0.068 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain CBM-like PF14683.1 EKG14851.1 - 1.4e-38 132.1 0.0 1.9e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EKG14851.1 - 2.1e-18 66.1 0.1 4.8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EKG14851.1 - 7e-12 45.2 1.5 6.8e-09 35.6 0.3 2.8 2 1 1 3 3 3 2 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 EKG14851.1 - 0.0015 18.6 0.3 0.0026 17.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) DUF2012 PF09430.5 EKG14851.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) GSH_synth_ATP PF03917.12 EKG14853.1 - 1.6e-42 145.4 0.0 2.7e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EKG14853.1 - 4.7e-15 55.5 0.0 3e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic glutathione synthase adh_short_C2 PF13561.1 EKG14854.1 - 1.3e-08 34.9 0.0 1.4e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG14854.1 - 4e-05 23.5 0.0 7.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.20 EKG14855.1 - 8.2e-12 45.3 1.0 9.6e-12 45.1 0.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG14855.1 - 1.5e-05 24.7 0.2 1.9e-05 24.4 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG14855.1 - 4.1e-05 23.4 0.0 4.6e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EKG14855.1 - 5.9e-05 22.7 0.0 7.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EKG14855.1 - 0.007 16.7 0.0 0.0082 16.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EKG14855.1 - 0.013 14.9 0.2 0.014 14.8 0.1 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_26 PF13659.1 EKG14855.1 - 0.054 13.5 0.2 0.066 13.2 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Mur_ligase PF01225.20 EKG14855.1 - 0.1 12.6 0.2 0.16 12.0 0.2 1.4 1 1 0 1 1 1 0 Mur ligase family, catalytic domain DUF1638 PF07796.6 EKG14855.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) HET PF06985.6 EKG14856.1 - 3.5e-22 79.0 0.1 6.5e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank PF00023.25 EKG14858.1 - 3.9e-08 32.6 0.0 2e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EKG14858.1 - 3.9e-06 27.0 0.0 1.1e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKG14858.1 - 0.00078 19.4 0.1 0.058 13.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EKG14858.1 - 0.0084 16.3 0.0 0.037 14.3 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG14858.1 - 0.025 15.0 0.0 0.35 11.4 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DEAD PF00270.24 EKG14864.1 - 1.2e-41 142.0 0.1 1.9e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG14864.1 - 6.2e-23 80.4 0.0 2.5e-12 46.4 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EKG14864.1 - 0.0002 21.2 0.3 0.0034 17.2 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 EKG14864.1 - 0.0019 16.3 0.9 0.003 15.6 0.6 1.2 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.7 EKG14864.1 - 0.03 13.4 12.2 0.016 14.3 6.9 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Hist_deacetyl PF00850.14 EKG14866.1 - 1.4e-79 267.6 0.0 2.1e-79 267.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DnaJ PF00226.26 EKG14867.1 - 1.4e-21 75.9 4.3 2.4e-21 75.2 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1183 PF06682.7 EKG14867.1 - 0.98 8.9 4.1 1.4 8.4 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF3278 PF11683.3 EKG14870.1 - 0.19 11.7 0.0 0.19 11.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3278) HET PF06985.6 EKG14871.1 - 2.9e-24 85.7 0.0 5.2e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LRR_4 PF12799.2 EKG14872.1 - 3.5e-11 42.4 14.8 8.5e-08 31.6 3.6 2.8 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG14872.1 - 6.7e-10 38.5 5.5 6.7e-10 38.5 3.8 2.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EKG14872.1 - 2.1e-05 23.9 8.6 0.19 11.9 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 EKG14872.1 - 0.0028 17.5 12.3 0.37 11.1 0.1 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EKG14872.1 - 2 8.7 4.5 4 7.8 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeat AAA_31 PF13614.1 EKG14873.1 - 0.0022 17.9 0.2 0.0087 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Varsurf_PPLC PF03490.8 EKG14873.1 - 0.0024 17.4 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Phage_tail_2 PF06199.6 EKG14873.1 - 0.046 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Phage major tail protein 2 SyrA PF11089.3 EKG14877.1 - 2.5 7.9 8.7 2.8 7.8 0.3 3.0 3 0 0 3 3 3 0 Exopolysaccharide production repressor YhhN PF07947.9 EKG14877.1 - 3 7.1 12.2 1.6 8.0 5.9 1.9 1 1 1 2 2 2 0 YhhN-like protein LysM PF01476.15 EKG14878.1 - 7.8e-31 105.7 1.5 1.8e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 LysM domain MFS_1 PF07690.11 EKG14879.1 - 1.7e-05 23.7 1.1 2.2e-05 23.3 0.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EKG14879.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1228) TerC PF03741.11 EKG14881.1 - 0.05 13.0 0.1 0.099 12.0 0.0 1.5 1 1 0 1 1 1 0 Integral membrane protein TerC family MFS_1 PF07690.11 EKG14881.1 - 0.083 11.5 3.9 0.12 11.0 2.7 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2269 PF10027.4 EKG14881.1 - 0.099 12.4 3.2 0.49 10.1 0.8 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF485 PF04341.7 EKG14881.1 - 0.099 12.3 1.0 0.71 9.6 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function, DUF485 ABC2_membrane_5 PF13346.1 EKG14881.1 - 0.11 11.7 0.7 0.16 11.2 0.5 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3054 PF11255.3 EKG14881.1 - 0.14 12.0 0.9 0.19 11.6 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3054) DUF4381 PF14316.1 EKG14881.1 - 0.16 12.0 0.6 0.29 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Srg PF02118.16 EKG14881.1 - 0.18 11.1 1.7 0.62 9.4 0.8 1.9 2 1 0 2 2 2 0 Srg family chemoreceptor YwiC PF14256.1 EKG14881.1 - 0.95 9.5 4.3 27 4.8 3.0 2.3 1 1 0 1 1 1 0 YwiC-like protein Polysacc_synt_C PF14667.1 EKG14881.1 - 5.2 6.8 7.0 16 5.3 3.5 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain HsbA PF12296.3 EKG14883.1 - 7.4e-13 48.4 0.9 1.2e-12 47.7 0.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Reo_sigmaC PF04582.7 EKG14883.1 - 0.025 13.7 0.6 0.034 13.3 0.4 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FliG_M PF14841.1 EKG14883.1 - 0.045 13.7 0.4 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 FliG middle domain Acetyltransf_1 PF00583.19 EKG14884.1 - 3.8e-06 26.8 0.2 6.7e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG14884.1 - 0.00012 22.2 0.0 0.00024 21.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG14884.1 - 0.0051 16.9 0.0 0.031 14.4 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain p450 PF00067.17 EKG14885.1 - 1e-54 185.8 0.0 1.2e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EKG14886.1 - 1.1e-31 109.6 0.0 1.6e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG14886.1 - 0.00061 19.6 12.5 0.00093 19.0 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF547 PF04784.9 EKG14886.1 - 0.0093 15.8 0.1 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Ribonuc_L-PSP PF01042.16 EKG14887.1 - 2.3e-19 69.3 0.1 2.7e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP AA_permease PF00324.16 EKG14888.1 - 4.6e-78 262.6 28.8 5.4e-78 262.4 20.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG14888.1 - 1.3e-18 66.8 29.7 1.6e-18 66.5 20.6 1.1 1 0 0 1 1 1 1 Amino acid permease YihI PF04220.7 EKG14890.1 - 0.13 11.5 1.5 0.092 12.0 0.1 1.4 2 0 0 2 2 2 0 Der GTPase activator (YihI) Rifin_STEVOR PF02009.11 EKG14891.1 - 9.7 5.7 5.6 3.8 7.0 2.1 1.5 1 1 0 1 1 1 0 Rifin/stevor family UBN2 PF14223.1 EKG14895.1 - 0.01 15.5 0.0 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type FAM177 PF14774.1 EKG14895.1 - 0.25 11.2 3.6 0.54 10.1 2.5 1.6 1 0 0 1 1 1 0 FAM177 family Pep3_Vps18 PF05131.9 EKG14897.1 - 3.2e-44 149.9 0.0 6.7e-44 148.8 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EKG14897.1 - 7.1e-09 35.3 8.8 8.8e-07 28.6 0.4 3.5 3 1 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EKG14897.1 - 2.6e-05 23.9 0.6 5.4e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKG14897.1 - 0.00042 19.9 0.8 0.0011 18.6 0.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DUF1664 PF07889.7 EKG14897.1 - 0.0077 16.0 0.7 0.017 14.9 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF2175 PF09943.4 EKG14897.1 - 0.008 16.2 3.1 0.038 14.0 0.1 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) Vps39_2 PF10367.4 EKG14897.1 - 0.016 15.3 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EKG14897.1 - 0.054 13.1 0.4 0.14 11.8 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 EKG14897.1 - 0.079 12.8 0.2 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-rbx1 PF12678.2 EKG14897.1 - 0.19 11.8 2.6 0.3 11.2 0.7 2.1 2 1 0 2 2 1 0 RING-H2 zinc finger zf-C4H2 PF10146.4 EKG14897.1 - 0.5 10.3 2.2 0.69 9.8 0.5 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein zf-C3HC4_2 PF13923.1 EKG14897.1 - 0.64 10.1 4.5 0.15 12.1 0.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) bZIP_1 PF00170.16 EKG14897.1 - 0.69 9.9 2.5 0.6 10.1 0.4 2.0 2 0 0 2 2 2 0 bZIP transcription factor zf-C3HC4_3 PF13920.1 EKG14897.1 - 0.79 9.4 2.5 0.53 9.9 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) dCMP_cyt_deam_1 PF00383.17 EKG14898.1 - 4.7e-10 39.0 0.1 6.5e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EKG14898.1 - 0.0051 16.4 0.7 0.0073 15.9 0.5 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Phospholip_A2_3 PF09056.6 EKG14899.1 - 9.8e-26 90.1 0.1 1.4e-25 89.6 0.1 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 MVL PF12151.3 EKG14899.1 - 0.086 12.5 1.7 0.19 11.4 1.2 1.5 1 0 0 1 1 1 0 Mannan-binding protein Glyco_hydro_43 PF04616.9 EKG14900.1 - 5.1e-42 143.9 5.8 5.8e-42 143.7 4.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 4HBT_3 PF13622.1 EKG14901.1 - 6.9e-51 173.4 0.1 7.9e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EKG14901.1 - 0.0034 17.4 1.2 0.01 15.9 0.1 2.0 2 0 0 2 2 2 1 Thioesterase superfamily Gmx_para_CXXCG PF09535.5 EKG14901.1 - 0.09 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) AMP-binding PF00501.23 EKG14902.1 - 1.5e-94 316.7 0.0 1.8e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG14902.1 - 1.2e-14 54.9 1.2 5.6e-14 52.8 0.1 2.7 3 1 1 4 4 4 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 EKG14905.1 - 1.1e-55 189.0 0.0 1.3e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EKG14906.1 - 4.5e-28 97.7 0.0 6.3e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKG14906.1 - 6.4e-23 80.9 0.0 9.4e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EKG14906.1 - 0.00021 21.4 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 EKG14907.1 - 2e-12 46.5 0.0 3.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EKG14907.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CAP PF00188.21 EKG14910.1 - 2.1e-20 73.4 3.3 4e-20 72.5 2.3 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family GMC_oxred_N PF00732.14 EKG14911.1 - 3.1e-54 184.1 0.0 3.5e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG14911.1 - 2.8e-05 23.1 1.0 0.0081 15.0 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EKG14911.1 - 0.00015 21.7 0.2 0.0079 16.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG14911.1 - 0.00022 21.1 0.4 0.0008 19.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG14911.1 - 0.0014 17.6 1.3 0.012 14.5 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG14911.1 - 0.01 15.8 0.2 0.28 11.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG14911.1 - 0.02 13.3 0.7 0.02 13.3 0.5 1.4 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EKG14911.1 - 0.036 12.9 0.2 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EKG14911.1 - 0.037 13.1 0.1 0.076 12.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family GMC_oxred_C PF05199.8 EKG14912.1 - 2e-32 112.4 0.0 3.3e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase MutS_V PF00488.16 EKG14913.1 - 3.7e-73 245.7 0.1 5.2e-73 245.3 0.1 1.2 1 0 0 1 1 1 1 MutS domain V AAA_22 PF13401.1 EKG14913.1 - 0.019 15.0 0.1 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain MutS_III PF05192.13 EKG14913.1 - 0.098 12.4 0.5 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 MutS domain III MutS_IV PF05190.13 EKG14913.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 MutS family domain IV MutS_III PF05192.13 EKG14914.1 - 1.6e-19 70.5 0.9 2.9e-19 69.6 0.6 1.5 1 1 0 1 1 1 1 MutS domain III Epsilon_antitox PF08998.6 EKG14914.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial epsilon antitoxin WD40 PF00400.27 EKG14915.1 - 2e-84 274.7 18.0 1.7e-13 49.8 0.3 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EKG14915.1 - 5.4e-07 29.5 0.1 0.0094 15.6 0.0 3.4 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EKG14915.1 - 1.5e-06 26.6 8.9 0.095 10.8 0.0 5.2 3 3 2 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.7 EKG14915.1 - 0.0039 17.1 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EKG14915.1 - 0.017 15.0 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain TFIIIC_delta PF12657.2 EKG14915.1 - 0.034 13.8 2.8 1.7 8.2 0.6 3.8 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Nucleoporin_N PF08801.6 EKG14915.1 - 0.035 12.8 0.3 1.4 7.5 0.3 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Apc4_WD40 PF12894.2 EKG14915.1 - 0.054 13.0 0.0 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SPO11_like PF03533.9 EKG14916.1 - 0.49 10.2 2.5 31 4.5 0.3 3.4 3 0 0 3 3 3 0 SPO11 homologue cobW PF02492.14 EKG14917.1 - 1.3e-39 135.4 0.0 1.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKG14917.1 - 5.2e-05 23.3 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG14917.1 - 0.0011 18.6 0.2 0.0023 17.6 0.1 1.6 1 1 0 1 1 1 1 Part of AAA domain MobB PF03205.9 EKG14917.1 - 0.0024 17.6 0.0 0.005 16.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EKG14917.1 - 0.0072 15.7 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Viral_helicase1 PF01443.13 EKG14917.1 - 0.0083 15.6 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 EKG14917.1 - 0.017 14.6 0.2 0.28 10.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EKG14917.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKG14917.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EKG14917.1 - 0.047 14.0 0.2 0.13 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG14917.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 EKG14917.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_11 PF13086.1 EKG14917.1 - 0.12 11.8 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Endonuclease_7 PF02945.10 EKG14917.1 - 0.3 10.8 4.9 2.5 7.8 0.6 2.3 2 0 0 2 2 2 0 Recombination endonuclease VII RTA1 PF04479.8 EKG14918.1 - 7e-26 91.1 2.6 7.7e-26 90.9 1.8 1.0 1 0 0 1 1 1 1 RTA1 like protein Cation_ATPase_C PF00689.16 EKG14918.1 - 0.00035 20.1 0.3 0.00048 19.6 0.2 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus SLAC1 PF03595.12 EKG14918.1 - 0.046 12.3 3.5 0.055 12.1 2.4 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel UPF0220 PF05255.6 EKG14918.1 - 0.07 12.3 0.6 0.11 11.7 0.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0220) DUF1632 PF07857.7 EKG14918.1 - 0.1 11.8 1.4 0.21 10.7 0.2 1.8 2 0 0 2 2 2 0 CEO family (DUF1632) PEX11 PF05648.9 EKG14918.1 - 0.12 11.6 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF996 PF06195.8 EKG14918.1 - 0.14 12.1 4.9 4.5 7.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF308 PF03729.8 EKG14918.1 - 0.2 11.6 6.8 6.4 6.8 0.0 3.0 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) zf-DHHC PF01529.15 EKG14918.1 - 2.6 7.3 4.9 15 4.9 3.9 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase Syja_N PF02383.13 EKG14919.1 - 7.5e-86 287.7 0.0 1.2e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EKG14919.1 - 3.9e-25 89.2 0.0 7.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Metallophos PF00149.23 EKG14919.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Zn_clus PF00172.13 EKG14920.1 - 0.13 12.1 9.4 0.24 11.3 6.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpB2 PF09487.5 EKG14920.1 - 0.38 10.9 2.5 9.6 6.4 0.3 2.7 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) C2 PF00168.25 EKG14921.1 - 1.4e-19 69.7 0.1 8.7e-11 41.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain SKG6 PF08693.5 EKG14921.1 - 0.52 9.6 6.1 1.3 8.4 4.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DnaJ PF00226.26 EKG14922.1 - 1.7e-11 43.6 2.3 8.6e-11 41.4 1.6 2.2 1 1 0 1 1 1 1 DnaJ domain Tom5 PF10642.4 EKG14922.1 - 0.037 13.6 0.4 4.9 6.8 0.0 2.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase PRA1 PF03208.14 EKG14923.1 - 3.8e-42 143.2 1.1 4.2e-42 143.0 0.8 1.0 1 0 0 1 1 1 1 PRA1 family protein UPF0182 PF03699.8 EKG14923.1 - 0.072 11.0 0.2 0.079 10.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Sarcoglycan_1 PF04790.8 EKG14923.1 - 0.13 11.4 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Menin PF05053.8 EKG14925.1 - 0.39 8.8 3.0 0.53 8.4 2.1 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 EKG14926.1 - 3.3e-68 229.6 0.0 5.7e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG14926.1 - 3.5e-50 170.4 0.0 5.1e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG14926.1 - 0.00012 21.2 0.0 0.0029 16.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RhoGAP PF00620.22 EKG14930.1 - 5.4e-41 139.7 0.1 1.1e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EKG14930.1 - 1.9e-11 44.1 0.0 4.7e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKG14930.1 - 1.5e-07 31.6 0.0 5.1e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 EKG14930.1 - 0.041 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 PX domain PMP1_2 PF08114.6 EKG14931.1 - 0.00022 20.6 3.0 0.00022 20.6 2.1 1.6 1 1 1 2 2 2 1 ATPase proteolipid family UPF0542 PF15086.1 EKG14931.1 - 0.0024 17.5 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 DUF2393 PF09624.5 EKG14931.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF4293 PF14126.1 EKG14931.1 - 0.036 13.9 0.1 0.041 13.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF2207 PF09972.4 EKG14931.1 - 0.051 12.1 0.0 0.057 11.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Synaptobrevin PF00957.16 EKG14931.1 - 0.083 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Synaptobrevin ODV-E18 PF10717.4 EKG14931.1 - 0.12 11.8 0.7 0.17 11.3 0.1 1.5 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF1049 PF06305.6 EKG14931.1 - 0.14 11.6 2.5 0.14 11.6 1.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) TMEMspv1-c74-12 PF11044.3 EKG14931.1 - 0.6 9.6 2.4 0.91 9.1 1.7 1.2 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein RELT PF12606.3 EKG14931.1 - 2.1 7.5 4.5 3.3 6.9 3.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 PTR2 PF00854.16 EKG14933.1 - 1.1e-47 162.5 8.4 4.1e-47 160.7 5.8 1.8 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EKG14933.1 - 4e-09 35.6 21.0 4e-09 35.6 14.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 EKG14933.1 - 2 8.4 10.0 8.3 6.4 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) UBA_4 PF14555.1 EKG14934.1 - 4.9e-15 54.7 0.3 1e-14 53.7 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EKG14934.1 - 5.5e-13 48.7 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EKG14934.1 - 2.7e-07 30.5 0.0 9e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 UBX domain Thioredox_DsbH PF03190.10 EKG14934.1 - 0.0066 16.1 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 EKG14934.1 - 0.015 15.5 0.0 0.048 13.8 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like domain Ecm29 PF13001.2 EKG14935.1 - 2.8e-134 448.3 0.0 5.8e-134 447.3 0.0 1.6 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EKG14935.1 - 2.6e-09 36.3 4.5 0.26 11.4 0.0 8.0 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EKG14935.1 - 6.5e-09 36.0 0.0 0.0011 19.3 0.0 5.2 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EKG14935.1 - 0.0009 18.6 0.2 0.61 9.4 0.0 3.5 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EKG14935.1 - 0.013 15.9 22.3 2 9.0 0.4 8.8 9 0 0 9 9 9 0 HEAT-like repeat Adaptin_N PF01602.15 EKG14935.1 - 0.043 12.1 0.0 1 7.5 0.0 2.7 3 0 0 3 3 3 0 Adaptin N terminal region V4R PF02830.13 EKG14935.1 - 0.29 10.9 0.0 0.75 9.6 0.0 1.6 1 0 0 1 1 1 0 V4R domain zf-C3HC4_2 PF13923.1 EKG14936.1 - 1.6e-05 24.8 12.7 1.6e-05 24.8 8.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG14936.1 - 1.7e-05 24.5 12.0 1.7e-05 24.5 8.3 2.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 EKG14936.1 - 2.9e-05 23.8 12.2 2.9e-05 23.8 8.5 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EKG14936.1 - 7.9e-05 22.2 11.3 7.9e-05 22.2 7.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG14936.1 - 0.00013 21.6 10.6 0.00013 21.6 7.4 2.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG14936.1 - 0.0005 19.6 8.7 0.0005 19.6 6.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG14936.1 - 0.0016 18.1 4.5 0.0034 17.0 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EKG14936.1 - 0.11 12.3 7.9 0.076 12.8 1.8 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EKG14936.1 - 0.42 10.7 8.5 1.2 9.2 3.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger 2OG-FeII_Oxy_3 PF13640.1 EKG14937.1 - 0.01 16.3 0.0 0.02 15.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-Fe_Oxy_2 PF10014.4 EKG14937.1 - 0.034 13.5 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase DUF2704 PF10866.3 EKG14937.1 - 0.04 13.3 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2704) CHCH PF06747.8 EKG14938.1 - 8.5e-07 28.7 3.7 1.8e-06 27.7 2.0 1.8 1 1 1 2 2 2 1 CHCH domain DUF1903 PF08991.5 EKG14938.1 - 6.7e-05 22.9 2.2 8.7e-05 22.6 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Cmc1 PF08583.5 EKG14938.1 - 0.088 12.5 3.2 1.4 8.7 1.7 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EKG14938.1 - 0.096 12.7 2.1 0.14 12.2 1.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 EKG14938.1 - 0.19 11.6 3.9 0.49 10.2 2.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) NatB_MDM20 PF09797.4 EKG14939.1 - 1.3e-39 135.9 4.3 1.8e-38 132.2 2.4 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EKG14939.1 - 8.6e-06 25.9 2.5 0.0041 17.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKG14939.1 - 2.3e-05 23.9 0.1 8.3e-05 22.1 0.0 2.1 1 0 0 1 1 1 1 TPR repeat TPR_20 PF14561.1 EKG14939.1 - 0.0046 17.0 1.1 0.045 13.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG14939.1 - 0.0082 16.7 0.0 0.044 14.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fungal_trans PF04082.13 EKG14941.1 - 7.7e-25 87.2 1.2 1.2e-24 86.6 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Proteasome PF00227.21 EKG14942.1 - 5e-37 127.0 0.0 5.9e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit WD40 PF00400.27 EKG14943.1 - 5.7e-32 108.4 4.1 5.4e-09 35.6 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKG14943.1 - 0.0036 17.0 0.0 0.99 9.2 0.0 2.8 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EKG14943.1 - 0.02 13.6 0.1 2.8 6.5 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 EKG14943.1 - 0.069 11.2 1.1 0.11 10.5 0.2 1.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Prenyltrans PF00432.16 EKG14944.1 - 3.1e-34 116.2 11.6 1.5e-07 30.8 0.0 7.0 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKG14944.1 - 1e-24 87.0 0.0 2.6e-15 56.7 0.0 3.4 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EKG14944.1 - 5.2e-07 29.6 0.0 0.00027 20.9 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like RhoGAP PF00620.22 EKG14945.1 - 2.2e-16 59.8 0.0 5e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EKG14945.1 - 3e-14 52.9 0.0 1.6e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EKG14945.1 - 4.7e-10 39.0 0.0 9.8e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KIP1 PF07765.7 EKG14945.1 - 0.074 12.8 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 KIP1-like protein DUF3993 PF13158.1 EKG14945.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Sipho_Gp157 PF05565.6 EKG14945.1 - 0.42 10.1 3.1 16 5.0 0.1 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 WD40 PF00400.27 EKG14948.1 - 7e-76 247.6 26.9 3.6e-09 36.1 0.1 12.5 13 1 0 13 13 13 11 WD domain, G-beta repeat Utp13 PF08625.6 EKG14948.1 - 8.9e-46 155.0 0.1 1.3e-45 154.4 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EKG14948.1 - 1.2e-10 40.2 10.4 0.063 11.4 0.4 7.3 2 2 3 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EKG14948.1 - 0.014 14.1 6.9 14 4.2 0.1 5.5 3 2 2 6 6 6 0 Nup133 N terminal like Vps16_C PF04840.7 EKG14948.1 - 0.2 10.5 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Vps16, C-terminal region Methyltransf_3 PF01596.12 EKG14949.1 - 6.2e-14 51.5 0.0 1e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EKG14949.1 - 1.3e-10 42.0 0.0 2.9e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_4 PF13535.1 EKG14949.1 - 1.1e-09 38.2 0.0 4.8e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG14949.1 - 2.5e-06 26.4 0.0 5.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Methyltransf_18 PF12847.2 EKG14949.1 - 0.04 14.4 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CmcI PF04989.7 EKG14949.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase DHQ_synthase PF01761.15 EKG14950.1 - 6.1e-54 182.6 0.0 9e-54 182.1 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EKG14950.1 - 3.2e-10 39.7 0.0 5.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Kinesin PF00225.18 EKG14951.1 - 4.6e-97 324.7 0.0 8.7e-97 323.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3138 PF11336.3 EKG14951.1 - 0.0013 17.0 1.7 0.0013 17.0 1.2 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3138) CCDC32 PF14989.1 EKG14951.1 - 0.0014 18.4 0.3 0.018 14.8 0.2 2.5 2 0 0 2 2 2 1 Coiled-coil domain containing 32 FlxA PF14282.1 EKG14951.1 - 0.14 12.1 5.9 0.1 12.5 0.6 3.1 3 1 1 4 4 4 0 FlxA-like protein IncA PF04156.9 EKG14951.1 - 4.1 6.9 13.0 4.4 6.8 0.3 2.5 2 0 0 2 2 2 0 IncA protein SAM_2 PF07647.12 EKG14953.1 - 5.5e-11 42.1 0.1 1.1e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EKG14953.1 - 4e-09 36.5 0.8 1e-08 35.1 0.2 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH PF00169.24 EKG14953.1 - 5.7e-05 23.2 0.1 0.00028 21.0 0.0 2.1 2 0 0 2 2 2 1 PH domain SAM_PNT PF02198.11 EKG14953.1 - 0.021 14.5 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Fungal_trans_2 PF11951.3 EKG14954.1 - 7.7e-87 291.3 1.0 1.1e-86 290.8 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG14954.1 - 5.7e-08 32.5 8.3 9.8e-08 31.7 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.1 EKG14956.1 - 3.4e-05 24.3 8.7 0.021 15.4 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 EKG14956.1 - 6.4e-05 22.8 6.8 0.00012 21.9 0.1 3.3 2 1 2 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EKG14956.1 - 0.0039 17.7 12.9 20 6.1 0.0 8.3 7 3 2 9 9 9 1 Tetratricopeptide repeat HAT PF02184.11 EKG14956.1 - 1.6 8.5 17.9 2.4 7.9 0.0 6.2 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat R3H PF01424.17 EKG14957.1 - 9.8e-17 60.4 0.1 2.2e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 R3H domain CDC27 PF09507.5 EKG14957.1 - 0.21 10.7 18.2 0.35 10.0 12.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 ATP-synt_S1 PF05827.7 EKG14959.1 - 9.3e-39 133.4 0.6 2e-38 132.3 0.4 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF732 PF05305.9 EKG14960.1 - 0.0047 16.9 3.6 0.5 10.4 0.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF732) tRNA-synt_1g PF09334.6 EKG14961.1 - 1.3e-109 366.4 0.0 2.2e-109 365.6 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EKG14961.1 - 7.4e-23 80.3 0.2 7.2e-11 40.8 0.0 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EKG14961.1 - 4.9e-06 25.8 0.0 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain AP_endonuc_2 PF01261.19 EKG14963.1 - 1.7e-36 125.5 0.0 2.5e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAHP_synth_1 PF00793.15 EKG14964.1 - 1.9e-102 341.5 0.1 2.3e-102 341.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF1205 PF06722.7 EKG14964.1 - 0.063 13.5 0.0 9.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1205) FAA_hydrolase PF01557.13 EKG14966.1 - 3.5e-53 180.2 0.1 4.9e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HSP20 PF00011.16 EKG14967.1 - 2.8e-21 75.2 1.0 1.9e-14 53.3 0.2 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family RNA_pol_L_2 PF13656.1 EKG14968.1 - 2.4e-20 71.7 0.0 3.1e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EKG14968.1 - 7.5e-07 28.1 0.0 1.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain AICARFT_IMPCHas PF01808.13 EKG14969.1 - 1.5e-113 379.0 0.0 2e-113 378.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EKG14969.1 - 3.6e-22 78.0 0.0 6.3e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain DUF3753 PF12575.3 EKG14969.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Peptidase_M1 PF01433.15 EKG14970.1 - 1.4e-139 465.5 0.1 2.3e-139 464.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EKG14970.1 - 4.1e-95 318.7 0.1 9.6e-95 317.5 0.0 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EKG14970.1 - 1.7e-20 73.3 0.1 7.6e-20 71.2 0.1 2.1 2 0 0 2 2 2 1 Peptidase MA superfamily CTP_transf_1 PF01148.15 EKG14971.1 - 2.2e-06 27.5 7.3 2.2e-05 24.2 0.8 3.2 4 0 0 4 4 4 2 Cytidylyltransferase family DUF3902 PF13042.1 EKG14971.1 - 0.00037 19.8 1.5 0.027 13.7 1.6 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3902) DUF2434 PF10361.4 EKG14971.1 - 0.28 10.2 4.6 1.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) NMO PF03060.10 EKG14972.1 - 1.5e-75 254.3 2.2 1.8e-75 254.1 1.5 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EKG14972.1 - 2.2e-07 30.0 0.0 2.9e-05 23.1 0.0 3.0 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PEP-utilizers PF00391.18 EKG14972.1 - 0.064 12.8 1.0 0.22 11.1 0.7 1.9 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain FMN_dh PF01070.13 EKG14972.1 - 0.12 11.2 4.9 0.22 10.3 3.4 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Taxilin PF09728.4 EKG14973.1 - 6.6e-86 288.1 61.2 9.6e-86 287.6 42.4 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein LPP PF04728.8 EKG14973.1 - 3.6 7.4 7.4 1.1 9.0 0.1 3.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper M16C_assoc PF08367.6 EKG14974.1 - 3.9e-61 206.0 0.1 5.5e-61 205.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EKG14974.1 - 1.2e-31 109.8 0.0 6.6e-18 65.0 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EKG14974.1 - 7.7e-10 38.7 0.0 1.1e-07 31.7 0.0 2.6 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) ATP_bind_4 PF01902.12 EKG14976.1 - 1.6e-20 73.4 0.0 5.8e-15 55.2 0.0 2.2 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EKG14976.1 - 3.9e-09 36.3 0.0 6.4e-05 22.6 0.0 3.1 3 1 0 3 3 3 2 Endoribonuclease L-PSP zf-C2H2 PF00096.21 EKG14977.1 - 1.6e-12 46.9 14.6 4.2e-07 29.9 1.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG14977.1 - 1.4e-10 40.7 11.2 0.00011 22.2 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG14977.1 - 9.2e-07 28.8 14.3 5.9e-05 23.1 4.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EKG14977.1 - 1.3e-05 25.1 7.0 0.01 15.9 1.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG14977.1 - 4e-05 23.6 6.3 0.0025 17.9 0.4 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EKG14977.1 - 0.00022 21.0 11.1 0.00028 20.6 0.6 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger LIM PF00412.17 EKG14977.1 - 0.12 12.4 3.9 0.27 11.3 2.7 1.6 1 0 0 1 1 1 0 LIM domain Hex_IIIa PF02455.11 EKG14977.1 - 0.55 8.8 4.8 0.81 8.3 3.3 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PITH PF06201.8 EKG14979.1 - 2.3e-40 137.8 0.0 4.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EKG14979.1 - 1e-28 99.0 0.0 1.6e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKG14979.1 - 1.7e-08 34.4 0.0 0.00012 22.0 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EKG14979.1 - 1.3e-05 25.3 0.3 0.00012 22.2 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EKG14979.1 - 0.0012 18.5 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EKG14979.1 - 0.0018 18.2 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EKG14979.1 - 0.0059 16.1 0.2 0.85 9.1 0.0 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 EKG14979.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Pex2_Pex12 PF04757.9 EKG14982.1 - 7.4e-44 149.8 3.6 1.1e-43 149.3 2.5 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EKG14982.1 - 5.9e-11 42.0 12.5 1e-10 41.2 8.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKG14982.1 - 4.6e-10 39.3 12.7 7.9e-10 38.6 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG14982.1 - 9.4e-09 34.8 11.4 1.9e-08 33.8 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG14982.1 - 9.6e-08 31.5 13.7 1.5e-07 30.9 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG14982.1 - 3.2e-07 29.9 10.2 5.6e-07 29.1 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EKG14982.1 - 1.7e-05 24.4 2.5 1.7e-05 24.4 1.7 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EKG14982.1 - 3.6e-05 23.5 11.9 6.9e-05 22.6 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EKG14982.1 - 0.0012 18.9 11.4 0.0031 17.6 7.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EKG14982.1 - 0.021 14.5 7.3 0.044 13.5 5.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein p450 PF00067.17 EKG14983.1 - 6e-78 262.4 0.0 7.2e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 K-box PF01486.12 EKG14983.1 - 0.1 12.3 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 K-box region Pkinase PF00069.20 EKG14984.1 - 1.5e-76 256.9 0.0 2.2e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG14984.1 - 4.6e-36 124.2 0.0 6.2e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EKG14984.1 - 2.6e-14 53.0 0.1 6.4e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EKG14984.1 - 6.8e-10 38.3 0.0 5.5e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EKG14984.1 - 0.0026 16.6 0.1 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 EKG14984.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_5 PF13893.1 EKG14985.1 - 7.8e-09 35.2 0.1 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG14985.1 - 2.3e-08 33.5 0.0 4.4e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EKG14985.1 - 0.001 18.6 0.1 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Calcipressin RRM_6 PF14259.1 EKG14985.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKG14985.1 - 0.038 13.7 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 WD40 PF00400.27 EKG14986.1 - 5.1e-24 83.2 9.9 7.9e-08 31.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Rax2 PF12768.2 EKG14986.1 - 0.023 13.9 0.0 0.075 12.2 0.0 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity MDM31_MDM32 PF08118.6 EKG14987.1 - 2.7e-192 639.7 0.3 3.1e-192 639.5 0.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EKG14988.1 - 2.9e-05 23.6 0.6 6.2e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 KH domain DUF2235 PF09994.4 EKG14989.1 - 2e-106 355.4 0.9 4.6e-106 354.2 0.6 1.6 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 EKG14991.1 - 2.2e-106 356.3 0.0 3.5e-104 349.1 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EKG14991.1 - 3.8e-05 22.4 0.0 8.7e-05 21.2 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 ABC_sub_bind PF04392.7 EKG14991.1 - 0.14 11.0 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein Proteasome PF00227.21 EKG14992.1 - 6.8e-30 103.7 0.0 2.4e-29 101.9 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit HCNGP PF07818.8 EKG14993.1 - 7.9e-30 102.7 0.1 1.1e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein DUF1509 PF07420.6 EKG14993.1 - 1.2 8.3 9.7 1.5 8.0 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Proteasome PF00227.21 EKG14994.1 - 6.8e-28 97.2 0.0 2.3e-27 95.5 0.0 1.7 1 1 0 1 1 1 1 Proteasome subunit Frag1 PF10277.4 EKG14995.1 - 3.3e-46 157.4 10.2 4e-46 157.2 7.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2899 PF11449.3 EKG14995.1 - 0.015 14.5 0.9 0.026 13.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) DUF3487 PF11990.3 EKG14995.1 - 0.25 10.7 0.1 0.25 10.7 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) DUF1469 PF07332.6 EKG14995.1 - 7.4 6.3 11.6 1.1 9.0 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Ribosomal_L36e PF01158.13 EKG14996.1 - 2.6e-34 117.0 9.3 1.3e-28 98.8 3.2 2.0 2 0 0 2 2 2 2 Ribosomal protein L36e MRP-L28 PF09812.4 EKG14996.1 - 0.45 10.3 6.5 0.49 10.2 1.1 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L28 TUG-UBL1 PF11470.3 EKG14997.1 - 4.3e-26 90.6 0.2 2.6e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EKG14997.1 - 3.7e-07 30.1 0.0 6e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 UBX domain RBD PF02196.10 EKG14997.1 - 0.042 13.6 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain Cytochrom_C1 PF02167.10 EKG14999.1 - 1.6e-82 276.4 0.0 1.9e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EKG14999.1 - 0.01 16.0 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III DUF202 PF02656.10 EKG14999.1 - 0.099 12.8 0.5 18 5.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Pkinase PF00069.20 EKG15000.1 - 3.9e-69 232.6 0.0 3.9e-69 232.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG15000.1 - 8.5e-43 146.2 0.0 1.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG15000.1 - 6.9e-12 44.9 0.0 1.8e-10 40.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKG15000.1 - 5.3e-06 26.3 4.9 0.045 13.4 0.1 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 EKG15000.1 - 0.011 15.0 1.3 0.084 12.2 0.0 2.6 2 1 1 3 3 3 0 RIO1 family Kdo PF06293.9 EKG15000.1 - 0.024 13.7 0.8 0.21 10.6 0.0 2.4 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EKG15000.1 - 0.036 12.8 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GTP_EFTU PF00009.22 EKG15001.1 - 2e-38 131.7 0.0 3.2e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EKG15001.1 - 2.6e-36 123.5 0.2 5.7e-36 122.4 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EKG15001.1 - 2.2e-12 46.8 0.7 5.4e-12 45.6 0.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKG15001.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKG15001.1 - 0.096 12.4 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Connexin_CCC PF10582.4 EKG15001.1 - 0.17 11.6 0.5 0.42 10.4 0.4 1.6 1 0 0 1 1 1 0 Gap junction channel protein cysteine-rich domain INSIG PF07281.7 EKG15002.1 - 2.2e-58 196.8 0.7 2.9e-58 196.4 0.5 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) FA_desaturase PF00487.19 EKG15002.1 - 0.05 13.0 0.8 0.086 12.2 0.5 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Pex14_N PF04695.8 EKG15002.1 - 1.6 8.7 6.4 1.7 8.6 0.0 2.8 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AA_permease PF00324.16 EKG15004.1 - 3.9e-150 500.3 37.9 4.4e-150 500.1 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG15004.1 - 1.2e-39 136.1 40.8 1.5e-39 135.7 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease SPC12 PF06645.8 EKG15004.1 - 0.57 10.0 0.0 0.57 10.0 0.0 3.9 4 1 0 5 5 5 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF373 PF04123.8 EKG15004.1 - 1.3 7.9 8.8 0.91 8.4 4.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF373) IMS PF00817.15 EKG15007.1 - 3.4e-20 72.3 0.0 6.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EKG15007.1 - 1.2e-12 47.8 0.2 3e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EKG15007.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Nitroreductase PF00881.19 EKG15008.1 - 1.7e-10 40.9 0.0 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family YjeF_N PF03853.10 EKG15009.1 - 2.3e-35 121.6 0.0 3.1e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF429 PF04250.8 EKG15009.1 - 0.091 12.0 0.2 1.3 8.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF429) Ribosomal_S16 PF00886.14 EKG15010.1 - 3.1e-26 90.8 0.1 5.2e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 Aa_trans PF01490.13 EKG15011.1 - 2.1e-94 316.3 13.0 3e-94 315.7 9.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_1 PF00018.23 EKG15013.1 - 6.4e-10 38.2 0.0 1.1e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG15013.1 - 2.9e-07 29.9 0.0 6.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKG15013.1 - 3.2e-07 29.7 0.0 6.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Sugar_tr PF00083.19 EKG15013.1 - 0.025 13.1 5.1 0.034 12.7 3.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF4311 PF14188.1 EKG15013.1 - 0.026 14.0 0.6 0.038 13.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) DUF2069 PF09842.4 EKG15013.1 - 0.028 14.3 1.1 0.35 10.8 0.6 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) MFS_1 PF07690.11 EKG15013.1 - 0.028 13.1 9.3 0.04 12.6 6.4 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Dispanin PF04505.7 EKG15013.1 - 0.31 10.6 7.7 0.052 13.0 1.3 2.6 2 1 0 2 2 2 0 Interferon-induced transmembrane protein Herpes_LMP1 PF05297.6 EKG15013.1 - 0.69 8.7 3.4 1.4 7.7 0.0 2.0 1 1 1 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) 7tm_6 PF02949.15 EKG15013.1 - 2.6 6.7 7.4 0.23 10.2 0.7 1.9 1 1 1 2 2 2 0 7tm Odorant receptor DUF3311 PF11755.3 EKG15013.1 - 3.4 7.2 8.9 7.1 6.2 2.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3311) DUF3784 PF12650.2 EKG15013.1 - 6.2 6.8 7.7 4.1 7.4 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Chitin_bind_1 PF00187.14 EKG15015.1 - 0.0014 18.5 14.4 0.0029 17.5 10.0 1.5 1 0 0 1 1 1 1 Chitin recognition protein Macoilin PF09726.4 EKG15015.1 - 9.3 4.3 6.5 14 3.8 4.5 1.2 1 0 0 1 1 1 0 Transmembrane protein CN_hydrolase PF00795.17 EKG15018.1 - 2.6e-38 131.2 0.0 3.2e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NmrA PF05368.8 EKG15019.1 - 1.2e-34 119.6 0.2 1.4e-34 119.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG15019.1 - 4.6e-08 33.2 0.1 8.2e-08 32.4 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG15019.1 - 5.2e-07 29.3 0.2 0.00033 20.1 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EKG15019.1 - 5.9e-07 29.8 0.1 1.2e-06 28.8 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EKG15019.1 - 1.2e-05 24.1 0.1 1.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EKG15019.1 - 0.00086 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EKG15019.1 - 0.0016 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15019.1 - 0.0033 17.1 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 EKG15019.1 - 0.0051 16.7 0.4 0.013 15.3 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EKG15019.1 - 0.0075 15.2 0.2 0.011 14.7 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EKG15019.1 - 0.018 13.9 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Histone PF00125.19 EKG15020.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EKG15020.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EKG15020.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EKG15020.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EKG15020.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EKG15020.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SNF2_N PF00176.18 EKG15023.1 - 1.5e-28 99.4 0.0 8e-28 97.0 0.0 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG15023.1 - 0.0069 16.2 0.0 0.045 13.6 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain MFS_1 PF07690.11 EKG15024.1 - 6.7e-28 97.4 19.1 8e-28 97.1 13.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15024.1 - 9e-15 54.1 0.7 9.5e-15 54.1 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EKG15024.1 - 0.006 14.7 3.4 0.0074 14.4 2.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EKG15024.1 - 0.039 12.0 6.3 0.011 13.8 2.2 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Actino_peptide PF14408.1 EKG15024.1 - 0.079 12.8 0.9 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Velvet PF11754.3 EKG15026.1 - 0.00024 20.7 0.0 0.0003 20.4 0.0 1.3 1 1 0 1 1 1 1 Velvet factor OsmC PF02566.14 EKG15027.1 - 6.1e-13 48.8 0.0 1.4e-12 47.6 0.0 1.5 2 0 0 2 2 2 1 OsmC-like protein Beach PF02138.13 EKG15028.1 - 5.4e-113 376.9 0.1 1.4e-112 375.5 0.1 1.8 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 EKG15028.1 - 7.5e-11 42.5 1.0 1.5e-10 41.5 0.1 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 EKG15028.1 - 2.1e-10 40.3 2.0 2.2e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EKG15028.1 - 5.7e-06 26.0 6.5 0.0071 16.1 0.2 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat Laminin_G_2 PF02210.19 EKG15028.1 - 0.0072 16.3 0.4 0.9 9.5 0.0 2.6 2 0 0 2 2 2 1 Laminin G domain CPSF_A PF03178.10 EKG15028.1 - 0.17 10.9 0.0 12 4.9 0.0 2.2 1 1 1 2 2 2 0 CPSF A subunit region Peptidase_S8 PF00082.17 EKG15029.1 - 6.5e-54 182.9 12.4 1e-53 182.3 8.6 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EKG15029.1 - 7.7e-21 74.4 0.7 1.9e-20 73.2 0.5 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 RsbRD_N PF14361.1 EKG15029.1 - 0.01 16.2 0.7 4.2 7.8 0.1 2.6 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF3810 PF12725.2 EKG15031.1 - 0.0046 15.9 0.0 0.0046 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3810) peroxidase PF00141.18 EKG15032.1 - 1.3e-20 73.8 0.1 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MARVEL PF01284.18 EKG15034.1 - 1.1e-06 28.5 8.2 1.1e-06 28.5 5.7 2.1 2 0 0 2 2 2 2 Membrane-associating domain GST_C PF00043.20 EKG15035.1 - 2.7e-11 43.3 0.4 8.9e-11 41.6 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG15035.1 - 5.5e-08 32.9 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG15035.1 - 7.2e-08 32.2 0.3 2e-07 30.8 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG15035.1 - 1.1e-07 31.7 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG15035.1 - 9.2e-06 25.7 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG15035.1 - 0.00013 22.4 0.0 0.00029 21.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydro_lipase PF04083.11 EKG15036.1 - 6.8e-20 70.2 0.1 1.2e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EKG15036.1 - 1.2e-17 64.2 0.1 3.2e-17 62.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG15036.1 - 8.3e-09 35.6 0.0 1.9e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG15036.1 - 1.1e-05 25.2 0.0 5.1e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EKG15036.1 - 0.00026 20.4 0.1 0.011 15.2 0.1 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) CAP_N PF01213.14 EKG15036.1 - 0.3 10.3 1.8 0.61 9.3 1.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EKG15036.1 - 9.6 5.4 13.3 0.043 13.1 1.1 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Pet191_N PF10203.4 EKG15037.1 - 5.8e-16 58.2 0.2 7e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 zf-DHHC PF01529.15 EKG15038.1 - 2.2e-05 23.9 2.5 3.3e-05 23.3 1.8 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Glyco_transf_22 PF03901.12 EKG15038.1 - 0.066 12.1 0.4 0.08 11.9 0.3 1.1 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family Metallophos PF00149.23 EKG15039.1 - 4.8e-10 39.1 1.2 7.5e-10 38.5 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EKG15039.1 - 0.034 14.1 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain GST_N_2 PF13409.1 EKG15040.1 - 9.4e-19 67.1 0.0 2.2e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG15040.1 - 2.9e-10 39.8 0.0 1.3e-09 37.8 0.0 2.0 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG15040.1 - 2.8e-05 24.5 0.0 4.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG15040.1 - 0.0014 18.5 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG15040.1 - 0.0023 18.1 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Peroxidase_2 PF01328.12 EKG15041.1 - 4.2e-40 137.3 0.9 5.4e-40 136.9 0.6 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Response_reg PF00072.19 EKG15044.1 - 2.6e-20 72.4 0.0 2.1e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain adh_short_C2 PF13561.1 EKG15046.1 - 1.3e-25 90.5 0.2 1.7e-25 90.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG15046.1 - 1.9e-13 50.6 2.4 2.7e-13 50.1 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15046.1 - 5.6e-07 29.3 0.3 8.6e-07 28.7 0.2 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG15046.1 - 3.7e-05 23.8 1.4 0.00085 19.3 0.9 2.4 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EKG15046.1 - 0.0014 17.7 0.0 0.004 16.2 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EKG15046.1 - 0.0016 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 EKG15046.1 - 0.0023 17.5 0.0 0.0057 16.3 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EKG15046.1 - 0.0047 16.6 0.1 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG15046.1 - 0.0089 15.4 0.1 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EKG15046.1 - 0.072 13.1 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain DUF1620 PF07774.8 EKG15047.1 - 6.2e-74 247.9 0.0 1e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EKG15047.1 - 3.4e-25 88.8 8.9 6.7e-23 81.3 2.5 3.3 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.16 EKG15047.1 - 1.5e-05 24.2 3.3 7.5 6.2 0.0 5.7 6 0 0 6 6 6 3 PQQ enzyme repeat Ras PF00071.17 EKG15048.1 - 7e-51 171.8 0.0 8.4e-51 171.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG15048.1 - 6.6e-19 68.5 0.0 1.1e-18 67.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG15048.1 - 6.3e-09 35.3 0.0 7.1e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG15048.1 - 6.3e-06 25.7 0.0 6.4e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKG15048.1 - 0.00021 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKG15048.1 - 0.0019 18.3 0.1 0.02 15.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG15048.1 - 0.0054 16.7 0.2 2.1 8.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_32 PF13654.1 EKG15048.1 - 0.11 11.1 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Carboxyl_trans PF01039.17 EKG15049.1 - 4.5e-142 473.8 0.0 5.7e-142 473.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain zf-RING_2 PF13639.1 EKG15050.1 - 2.8e-06 27.0 6.7 5.5e-06 26.1 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 EKG15050.1 - 9.9e-06 25.2 2.1 9.9e-06 25.2 1.5 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EKG15050.1 - 0.0002 21.2 7.4 0.00038 20.3 5.2 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 EKG15050.1 - 0.024 14.6 6.3 0.061 13.3 3.9 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG15050.1 - 0.052 13.6 9.6 0.063 13.3 5.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger RFamide_26RFa PF11109.3 EKG15050.1 - 0.088 12.7 0.1 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 zf-C3HC4_3 PF13920.1 EKG15050.1 - 1.9 8.2 9.1 1.9 8.2 4.9 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Phe_hydrox_dim PF07976.7 EKG15051.1 - 1.9e-47 160.9 0.0 3.5e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 EKG15051.1 - 2.2e-40 138.7 0.0 2.8e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG15051.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DUF1682 PF07946.9 EKG15052.1 - 1.3e-105 352.7 0.6 1.5e-105 352.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2208 PF09973.4 EKG15052.1 - 0.21 10.8 0.0 0.21 10.8 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) APG6 PF04111.7 EKG15052.1 - 1.9 7.4 7.7 3 6.8 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 2-Hacid_dh_C PF02826.14 EKG15053.1 - 6.1e-57 191.6 0.0 8.1e-57 191.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG15053.1 - 7.3e-21 74.0 0.0 8.6e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EKG15053.1 - 3.3e-05 23.7 0.1 5.4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EKG15053.1 - 0.0039 17.5 0.2 0.0082 16.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EKG15053.1 - 0.005 16.2 0.2 0.0098 15.2 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EKG15053.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EKG15055.1 - 2.2e-27 96.0 0.2 3e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG15055.1 - 3.4e-12 46.6 0.0 4.4e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG15055.1 - 7.3e-11 42.0 0.1 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG15055.1 - 6.4e-05 22.5 0.0 0.00017 21.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG15055.1 - 0.001 19.0 0.1 0.0059 16.6 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EKG15055.1 - 0.0056 15.8 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EKG15055.1 - 0.076 12.8 0.3 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EKG15055.1 - 0.082 11.7 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 EKG15056.1 - 1.3e-05 24.1 0.0 5.4e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Catalase PF00199.14 EKG15057.1 - 6.3e-167 555.0 0.2 8.1e-167 554.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EKG15057.1 - 6.4e-16 57.9 0.0 1.6e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive HAD_2 PF13419.1 EKG15058.1 - 3.6e-23 82.6 0.0 7.1e-23 81.7 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG15058.1 - 3.1e-11 44.1 0.0 1.5e-10 41.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG15058.1 - 1.4e-08 34.3 0.0 2.4e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EKG15058.1 - 0.00041 20.5 0.0 0.00054 20.1 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 EKG15058.1 - 0.0027 17.3 0.0 0.05 13.2 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase PHD PF00628.24 EKG15060.1 - 2.1e-10 40.1 2.2 4.6e-10 39.0 1.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EKG15060.1 - 0.0067 15.7 3.4 0.011 15.0 2.3 1.4 1 0 0 1 1 1 1 PHD-finger MFS_1 PF07690.11 EKG15061.1 - 1.2e-26 93.3 29.4 1.2e-26 93.3 20.4 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15061.1 - 0.0013 17.4 16.6 0.002 16.7 5.6 3.4 2 2 0 2 2 2 1 Sugar (and other) transporter DUF485 PF04341.7 EKG15061.1 - 5.3 6.8 11.3 0.41 10.3 1.6 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Glyco_hydro_10 PF00331.15 EKG15062.1 - 5.9e-91 304.8 5.1 6.6e-91 304.6 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.19 EKG15062.1 - 0.051 12.8 0.0 0.22 10.7 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF1777 PF08648.7 EKG15063.1 - 0.57 9.8 10.3 0.82 9.3 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DAO PF01266.19 EKG15064.1 - 3.4e-50 170.9 3.0 4.4e-50 170.5 2.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG15064.1 - 2.5e-06 26.6 0.1 4.7e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG15064.1 - 8.7e-06 25.6 0.1 2.6e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG15064.1 - 0.00056 20.0 0.0 0.78 9.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG15064.1 - 0.00093 18.3 0.1 0.0028 16.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EKG15064.1 - 0.0025 16.9 0.1 0.0049 15.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG15064.1 - 0.0026 17.6 0.2 0.012 15.5 0.1 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EKG15064.1 - 0.022 13.1 0.0 0.033 12.5 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 EKG15064.1 - 0.039 13.7 0.1 0.19 11.4 0.0 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EKG15064.1 - 0.053 13.9 0.4 0.47 10.8 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sulfatase PF00884.18 EKG15065.1 - 6e-23 81.5 0.0 4.9e-22 78.4 0.0 2.0 1 1 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EKG15065.1 - 0.00098 19.4 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 C-terminal region of aryl-sulfatase SMC_N PF02463.14 EKG15066.1 - 1.1e-58 198.1 42.3 2.8e-58 196.7 29.3 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKG15066.1 - 8.4e-32 109.6 0.1 4.4e-31 107.3 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EKG15066.1 - 9.4e-18 65.1 0.0 5.1e-09 36.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EKG15066.1 - 4.1e-13 50.1 27.1 4.1e-13 50.1 18.8 6.8 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EKG15066.1 - 0.00033 20.1 0.0 0.00075 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 EKG15066.1 - 0.0013 17.8 12.2 0.0013 17.8 8.5 7.2 3 2 3 7 7 7 2 Autophagy protein Apg6 Reo_sigmaC PF04582.7 EKG15066.1 - 0.13 11.3 28.3 0.053 12.6 0.4 5.4 3 2 2 7 7 7 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EKG15066.1 - 0.25 9.7 0.0 0.23 9.8 4.7 6.2 3 2 2 6 6 6 0 AAA domain ABC_tran PF00005.22 EKG15066.1 - 0.32 11.2 0.0 0.32 11.2 0.0 7.1 3 2 1 4 4 4 0 ABC transporter Glyco_hydro_16 PF00722.16 EKG15067.1 - 2e-45 154.3 4.3 3.8e-45 153.4 3.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Y_phosphatase3C PF13348.1 EKG15068.1 - 2.2e-15 56.4 0.2 5.1e-15 55.3 0.1 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Lipocalin_7 PF14651.1 EKG15068.1 - 0.09 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family PQ-loop PF04193.9 EKG15069.1 - 1.5e-12 46.8 0.3 1.8e-07 30.5 0.0 2.8 2 1 0 2 2 2 2 PQ loop repeat CitMHS PF03600.11 EKG15069.1 - 3.3 6.2 8.5 5.7 5.4 5.9 1.3 1 1 0 1 1 1 0 Citrate transporter WD40 PF00400.27 EKG15070.1 - 1.8e-07 30.7 0.2 0.00053 19.7 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Nbas_N PF15492.1 EKG15070.1 - 0.0027 16.8 0.0 1.3 8.0 0.0 2.2 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 EKG15071.1 - 4e-108 360.6 0.2 1e-107 359.3 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EKG15071.1 - 7e-05 22.7 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG15071.1 - 0.0038 16.6 0.0 0.092 12.1 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EKG15071.1 - 0.0048 16.0 0.5 0.018 14.2 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EKG15071.1 - 0.0068 16.2 5.9 0.89 9.3 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 EKG15071.1 - 0.013 15.6 0.1 0.053 13.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EKG15071.1 - 0.081 13.4 0.3 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 EKG15071.1 - 0.31 11.8 3.0 0.92 10.3 0.1 2.7 2 2 0 2 2 2 0 AAA domain DUF3653 PF12375.3 EKG15071.1 - 0.82 9.9 3.8 17 5.7 1.7 2.9 2 1 0 2 2 2 0 Phage protein COesterase PF00135.23 EKG15073.1 - 2.5e-79 267.4 0.0 3.3e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG15073.1 - 1.3e-07 31.4 0.6 1.1e-06 28.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG15073.1 - 0.021 14.5 0.1 0.037 13.7 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family AA_permease PF00324.16 EKG15074.1 - 2e-121 405.6 37.8 2.5e-121 405.3 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG15074.1 - 2.1e-37 128.7 42.6 2.6e-37 128.3 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_1 PF00583.19 EKG15075.1 - 5.9e-05 23.0 0.0 0.0005 20.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG15075.1 - 0.0038 17.3 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG15075.1 - 0.015 15.4 0.0 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EKG15075.1 - 0.083 12.6 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase RRM_1 PF00076.17 EKG15076.1 - 4.5e-20 71.0 0.0 8.7e-20 70.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG15076.1 - 2.1e-13 50.0 0.0 4e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG15076.1 - 2.8e-07 30.2 0.0 5.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Grp1_Fun34_YaaH PF01184.14 EKG15077.1 - 2.4e-39 134.8 19.1 2.8e-39 134.5 13.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.2 EKG15077.1 - 1.6 8.6 7.8 9.5 6.2 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Gly_transf_sug PF04488.10 EKG15078.1 - 2.1e-12 47.3 0.0 4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Annexin PF00191.15 EKG15079.1 - 4.6e-68 225.0 5.5 2.6e-22 78.4 0.0 4.5 4 1 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 EKG15079.1 - 0.053 13.7 0.1 3.7 7.8 0.0 3.2 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF2985 PF11204.3 EKG15080.1 - 2.8e-29 100.6 3.1 5.9e-29 99.6 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) DUF1682 PF07946.9 EKG15080.1 - 0.042 12.7 0.8 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Esterase_phd PF10503.4 EKG15081.1 - 2.2e-25 89.1 1.1 3.1e-25 88.7 0.7 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EKG15081.1 - 5.2e-11 42.1 0.8 9.4e-11 41.3 0.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG15081.1 - 5.2e-08 32.7 0.4 6.8e-08 32.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EKG15081.1 - 1.3e-05 24.1 0.3 2.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EKG15081.1 - 2.3e-05 24.4 0.1 4.1e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG15081.1 - 0.00016 21.2 0.1 0.00034 20.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EKG15081.1 - 0.0028 17.1 1.5 0.0036 16.7 0.6 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EKG15081.1 - 0.0036 16.9 0.1 0.0055 16.2 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKG15081.1 - 0.01 15.3 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EKG15082.1 - 4.8e-34 117.6 34.1 4.8e-34 117.6 23.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RTC PF01137.16 EKG15084.1 - 4.2e-43 146.7 0.0 1.2e-42 145.2 0.0 1.7 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase Transport_MerF PF11431.3 EKG15084.1 - 0.031 13.9 0.5 0.29 10.7 0.1 2.4 2 0 0 2 2 2 0 Membrane transport protein MerF tRNA-synt_1d PF00750.14 EKG15086.1 - 2.5e-77 260.1 15.1 3.8e-46 157.5 9.8 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EKG15086.1 - 4.4e-31 107.3 0.2 4.4e-31 107.3 0.1 2.8 2 1 1 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EKG15086.1 - 1.8e-11 44.4 0.0 5.9e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Nuc_deoxyrib_tr PF05014.10 EKG15087.1 - 0.00057 19.7 0.0 0.0007 19.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Glyco_transf_90 PF05686.7 EKG15089.1 - 4.4e-11 42.1 8.2 1.8e-09 36.7 3.8 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 HI0933_like PF03486.9 EKG15092.1 - 9.4e-05 21.0 0.1 0.00016 20.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EKG15092.1 - 0.00024 20.2 0.1 0.00044 19.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EKG15092.1 - 0.00025 21.1 0.1 0.00038 20.5 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG15092.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG15092.1 - 0.00068 18.7 0.1 0.00095 18.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EKG15092.1 - 0.0011 17.9 1.9 0.0016 17.3 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG15092.1 - 0.0012 18.7 0.1 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG15092.1 - 0.005 15.7 0.7 0.0061 15.5 0.4 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 EKG15092.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 GMC oxidoreductase FAD_oxidored PF12831.2 EKG15092.1 - 0.023 13.7 1.4 0.037 13.1 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG15092.1 - 0.027 13.3 0.4 0.04 12.8 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EKG15092.1 - 0.045 12.6 0.1 0.059 12.2 0.1 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EKG15092.1 - 0.11 12.2 1.0 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Methyltransf_23 PF13489.1 EKG15093.1 - 1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15093.1 - 1.7e-05 25.3 0.2 4.5e-05 23.9 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15093.1 - 5.1e-05 22.8 0.0 0.00014 21.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG15093.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 EKG15093.1 - 0.015 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EKG15093.1 - 0.024 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MamL-1 PF09596.5 EKG15093.1 - 0.024 14.4 0.1 0.041 13.6 0.1 1.3 1 0 0 1 1 1 0 MamL-1 domain MTS PF05175.9 EKG15093.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EKG15093.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MIP PF00230.15 EKG15094.1 - 4.4e-45 153.9 14.8 6.3e-45 153.4 10.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF342 PF03961.8 EKG15097.1 - 0.02 13.3 4.5 0.028 12.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MIP-T3 PF10243.4 EKG15097.1 - 0.47 8.8 34.6 0.69 8.3 24.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF106 PF01956.11 EKG15097.1 - 4.8 6.6 7.1 8.6 5.8 4.9 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 MFS_1 PF07690.11 EKG15099.1 - 3.7e-19 68.6 40.8 1e-17 63.9 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15099.1 - 8.7e-05 21.2 27.8 0.068 11.7 19.2 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15101.1 - 1.3e-28 99.8 30.2 1.7e-28 99.3 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15101.1 - 9.1e-05 21.2 19.1 0.00023 19.9 13.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4131 PF13567.1 EKG15101.1 - 3.5 6.9 12.4 0.27 10.6 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) AAA_12 PF13087.1 EKG15103.1 - 2.1e-38 131.6 0.0 4.5e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG15103.1 - 2.8e-22 79.4 0.3 1.4e-21 77.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG15103.1 - 5.5e-10 38.8 0.0 1.3e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKG15103.1 - 2e-07 30.7 0.0 2.2e-05 24.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EKG15103.1 - 0.00025 20.6 0.0 0.063 12.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EKG15103.1 - 0.0081 15.5 0.5 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ResIII PF04851.10 EKG15103.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EKG15103.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 EKG15103.1 - 0.018 14.3 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EKG15103.1 - 0.03 13.3 0.0 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 EKG15104.1 - 1.3e-14 53.4 10.1 0.00019 21.1 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat HemolysinCabind PF00353.14 EKG15104.1 - 0.53 10.8 6.6 0.42 11.1 0.5 3.2 1 1 1 2 2 2 0 Hemolysin-type calcium-binding repeat (2 copies) DUF1021 PF06257.6 EKG15105.1 - 0.032 13.9 0.1 0.071 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1021) BTB PF00651.26 EKG15106.1 - 1.6e-07 31.3 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF2233 PF09992.4 EKG15107.1 - 0.039 13.9 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2233) Ecm33 PF12454.3 EKG15107.1 - 1 9.2 6.2 0.1 12.5 1.0 1.8 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein RRM_1 PF00076.17 EKG15108.1 - 9.8e-17 60.3 0.0 1.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG15108.1 - 4e-12 45.9 0.0 6.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG15108.1 - 7.1e-07 28.9 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EKG15110.1 - 3.9e-32 108.9 14.9 1.2e-08 34.5 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EKG15110.1 - 0.037 13.3 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature RsbRD_N PF14361.1 EKG15112.1 - 0.03 14.7 0.1 0.03 14.7 0.1 2.3 2 1 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain CPSase_L_D2 PF02786.12 EKG15113.1 - 2.5e-72 242.5 0.0 3.8e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EKG15113.1 - 7.8e-36 122.3 0.0 2.2e-35 120.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EKG15113.1 - 1.1e-33 115.5 0.0 3.3e-33 114.0 0.0 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 EKG15113.1 - 1.4e-17 63.1 1.3 3.5e-17 61.8 0.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EKG15113.1 - 7.1e-17 61.7 0.0 1.4e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG15113.1 - 1.1e-10 40.8 0.0 1.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EKG15113.1 - 6.4e-10 38.7 0.0 1.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EKG15113.1 - 2.4e-07 30.2 0.0 4.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EKG15113.1 - 8.7e-07 28.5 0.1 0.00011 21.7 0.0 2.7 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 EKG15113.1 - 0.00012 21.4 3.4 0.043 13.1 0.3 2.7 2 1 1 3 3 3 2 HlyD family secretion protein RimK PF08443.6 EKG15113.1 - 0.00061 19.3 0.0 0.002 17.6 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EKG15113.1 - 0.00061 19.6 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 EKG15113.1 - 0.0046 16.6 0.3 0.048 13.3 0.3 2.3 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 EKG15113.1 - 0.01 16.1 0.1 5.6 7.3 0.0 2.9 2 0 0 2 2 2 1 HlyD family secretion protein Toxin_59 PF15537.1 EKG15113.1 - 0.019 15.0 0.0 0.077 13.0 0.0 2.0 2 0 0 2 2 2 0 Putative toxin 59 NQRA PF05896.6 EKG15113.1 - 0.022 13.9 0.3 0.039 13.1 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.4 EKG15113.1 - 0.054 13.1 0.3 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 EKG15113.1 - 0.066 12.3 0.2 0.23 10.5 0.2 1.8 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 EKG15113.1 - 0.097 12.3 0.3 0.27 10.9 0.2 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein adh_short PF00106.20 EKG15114.1 - 1.4e-24 86.8 1.1 1.9e-24 86.4 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG15114.1 - 2.4e-12 47.1 0.0 3.3e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG15114.1 - 1.1e-10 41.5 0.7 1.6e-10 40.9 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG15114.1 - 0.00019 21.5 0.3 0.021 14.8 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKG15114.1 - 0.011 15.5 1.0 0.023 14.4 0.7 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG15114.1 - 0.022 14.2 0.8 0.54 9.6 0.1 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF3693 PF12472.3 EKG15114.1 - 0.26 10.8 2.1 0.46 10.1 0.3 2.2 2 0 0 2 2 2 0 Phage related protein N2227 PF07942.7 EKG15116.1 - 3.5e-16 58.9 0.0 4.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein IIGP PF05049.8 EKG15116.1 - 0.073 11.8 0.1 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2666 PF10869.3 EKG15116.1 - 0.079 12.9 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Sugar_tr PF00083.19 EKG15118.1 - 2e-78 264.0 25.6 2.3e-78 263.8 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15118.1 - 8e-17 60.9 25.7 8e-17 60.9 17.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Ldh_2 PF02615.9 EKG15120.1 - 1.2e-101 339.7 0.0 1.4e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MFS_1 PF07690.11 EKG15121.1 - 3e-47 161.0 46.6 3e-47 161.0 32.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG15121.1 - 2.6e-21 75.5 24.0 3.5e-21 75.0 16.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG15121.1 - 4e-13 48.7 11.9 4e-13 48.7 8.2 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter DUF697 PF05128.7 EKG15121.1 - 4.6 6.7 7.0 4.5 6.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF697) adh_short PF00106.20 EKG15123.1 - 5.1e-31 107.8 2.8 6.3e-31 107.5 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG15123.1 - 8.2e-16 58.4 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG15123.1 - 5.5e-13 48.9 1.1 7.7e-13 48.5 0.8 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG15123.1 - 8.5e-06 25.3 0.2 2.9e-05 23.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG15123.1 - 0.00086 19.3 0.0 0.0029 17.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKG15123.1 - 0.003 17.2 0.4 0.0066 16.2 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SPOR PF05036.8 EKG15123.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Sporulation related domain FMO-like PF00743.14 EKG15124.1 - 3.6e-14 51.8 1.5 3.1e-13 48.7 0.3 2.6 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EKG15124.1 - 6.4e-14 52.5 0.0 1.4e-13 51.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG15124.1 - 9.9e-06 24.6 0.0 0.00079 18.4 0.0 3.3 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EKG15124.1 - 0.00021 21.2 0.5 0.0011 18.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EKG15124.1 - 0.027 14.5 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2576 PF10845.3 EKG15124.1 - 0.34 10.1 4.0 0.63 9.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2576) CNH PF00780.17 EKG15125.1 - 2.5e-77 259.9 0.0 3.9e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EKG15125.1 - 6e-28 97.9 0.0 9.4e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EKG15125.1 - 2.2e-14 53.5 0.0 5.5e-13 49.0 0.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EKG15125.1 - 7.8e-06 26.0 0.0 2.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 PH domain DLIC PF05783.6 EKG15126.1 - 7.8e-38 130.3 0.0 1e-34 120.0 0.0 3.1 2 2 0 3 3 3 2 Dynein light intermediate chain (DLIC) Bax1-I PF01027.15 EKG15127.1 - 6.5e-48 163.0 30.3 7.9e-48 162.7 21.0 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 EKG15127.1 - 0.049 13.0 0.1 0.19 11.1 0.1 2.1 1 0 0 1 1 1 0 Sporulation protein YhaL DUF2910 PF11139.3 EKG15127.1 - 0.37 9.8 8.0 0.045 12.8 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) DUF4233 PF14017.1 EKG15127.1 - 1.3 9.0 13.1 0.045 13.6 2.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF4233) DUF4131 PF13567.1 EKG15127.1 - 4.1 6.7 16.2 6.4 6.1 3.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF788 PF05620.6 EKG15128.1 - 8.8e-46 155.8 0.1 1e-45 155.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) TPR_11 PF13414.1 EKG15129.1 - 4.6e-39 131.8 22.7 2.4e-11 43.1 0.7 7.6 5 3 3 8 8 8 8 TPR repeat TPR_1 PF00515.23 EKG15129.1 - 1.2e-35 119.6 19.5 9.5e-08 31.3 0.1 9.8 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EKG15129.1 - 1.5e-35 118.2 27.3 9.7e-06 25.1 0.1 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 EKG15129.1 - 1.1e-28 99.2 18.0 1.8e-21 76.0 0.5 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EKG15129.1 - 3.9e-25 87.9 21.9 4.8e-07 30.2 0.0 8.4 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EKG15129.1 - 7e-24 83.5 17.2 0.00051 19.9 0.0 8.1 5 3 3 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.1 EKG15129.1 - 2.9e-22 76.7 2.1 0.0018 17.9 0.0 9.2 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKG15129.1 - 6.5e-18 63.6 22.8 0.054 14.1 0.0 10.6 5 2 6 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 EKG15129.1 - 9.2e-16 56.6 13.5 0.14 12.4 0.1 9.4 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EKG15129.1 - 7.3e-15 55.0 24.9 0.0022 18.2 1.0 7.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EKG15129.1 - 1.3e-12 47.2 10.2 0.5 10.9 0.1 8.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG15129.1 - 6.8e-12 44.2 12.3 0.027 14.2 0.0 8.1 9 1 0 9 9 9 3 Tetratricopeptide repeat APP_E2 PF12925.2 EKG15129.1 - 0.0028 17.2 1.3 0.0028 17.2 0.9 2.4 3 0 0 3 3 3 1 E2 domain of amyloid precursor protein TPR_9 PF13371.1 EKG15129.1 - 0.0095 15.7 15.3 0.47 10.3 1.0 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EKG15129.1 - 3.3 7.7 13.4 22 5.1 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Acyltransferase PF01553.16 EKG15130.1 - 3e-34 117.3 0.0 4.8e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1358 PF07096.6 EKG15130.1 - 0.45 10.2 6.1 0.28 10.8 2.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1358) DIT1_PvcA PF05141.7 EKG15131.1 - 9.9e-71 238.2 0.0 1.2e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 EKG15133.1 - 8.7e-21 73.9 0.0 1e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EKG15134.1 - 9e-34 116.7 21.6 1.3e-33 116.2 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15134.1 - 1e-13 50.6 8.1 1.9e-13 49.8 5.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EKG15134.1 - 0.00095 17.6 8.9 0.0018 16.7 5.1 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.8 EKG15134.1 - 0.0028 15.8 8.2 0.0039 15.3 5.7 1.1 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EKG15134.1 - 4.8 5.1 7.3 0.21 9.5 0.3 2.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_18 PF00704.23 EKG15136.1 - 7.3e-100 334.7 10.9 8.5e-100 334.5 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.20 EKG15137.1 - 3.6e-21 75.8 1.7 1e-20 74.3 1.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15137.1 - 6.8e-11 42.1 0.1 8.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG15137.1 - 9.2e-05 22.5 1.0 0.00018 21.5 0.7 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EKG15137.1 - 0.00011 22.1 0.1 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EKG15137.1 - 0.011 14.7 0.5 0.019 13.9 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Epimerase PF01370.16 EKG15137.1 - 0.032 13.6 0.0 0.041 13.3 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG15137.1 - 0.1 12.4 0.8 0.22 11.3 0.6 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Bactofilin PF04519.8 EKG15137.1 - 0.12 12.4 0.3 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Polymer-forming cytoskeletal NmrA PF05368.8 EKG15137.1 - 0.17 11.1 0.9 0.27 10.4 0.6 1.3 1 0 0 1 1 1 0 NmrA-like family Ctr PF04145.10 EKG15139.1 - 4.5e-40 137.0 2.1 5.5e-40 136.7 1.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Pex14_N PF04695.8 EKG15139.1 - 0.0062 16.5 0.1 0.01 15.9 0.0 1.4 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 EKG15139.1 - 0.022 12.6 0.7 0.029 12.2 0.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MacB_PCD PF12704.2 EKG15139.1 - 0.051 13.1 0.2 6.4 6.2 0.0 2.1 2 0 0 2 2 2 0 MacB-like periplasmic core domain DUF485 PF04341.7 EKG15139.1 - 0.32 10.7 4.2 8.6 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 PUL PF08324.6 EKG15140.1 - 4.3e-47 160.1 0.6 5.7e-47 159.7 0.4 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EKG15140.1 - 2.8e-44 147.4 9.2 4e-08 32.8 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 EKG15140.1 - 2.8e-44 149.8 0.2 5e-44 149.0 0.2 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.1 EKG15140.1 - 0.0021 17.8 0.0 4.4 7.1 0.0 4.1 1 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region BTB PF00651.26 EKG15141.1 - 1.8e-10 40.7 0.0 6.2e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain FAD-oxidase_C PF02913.14 EKG15142.1 - 9.1e-33 113.5 0.0 1.6e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EKG15142.1 - 5.5e-29 100.4 0.2 1e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain PB1 PF00564.19 EKG15142.1 - 0.16 11.6 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 PB1 domain Fungal_trans PF04082.13 EKG15143.1 - 1.6e-12 46.8 0.0 2.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Asp-Al_Ex PF06826.7 EKG15143.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.4 1 1 0 1 1 1 0 Predicted Permease Membrane Region Homeobox_KN PF05920.6 EKG15145.1 - 3.1e-18 65.1 0.2 3.1e-18 65.1 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EKG15145.1 - 2.1e-10 40.0 0.7 3.6e-10 39.3 0.1 1.7 2 0 0 2 2 2 1 Homeobox domain CAP-ZIP_m PF15255.1 EKG15145.1 - 0.095 12.6 5.8 0.23 11.3 4.0 1.7 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region Tyrosinase PF00264.15 EKG15146.1 - 3.2e-48 164.8 0.0 4.6e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Zn_peptidase_2 PF04298.7 EKG15148.1 - 0.22 10.8 2.0 0.28 10.5 1.4 1.1 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase Wzy_C PF04932.10 EKG15148.1 - 0.76 9.5 3.6 0.89 9.3 2.5 1.2 1 0 0 1 1 1 0 O-Antigen ligase Acetyltransf_1 PF00583.19 EKG15151.1 - 2.2e-12 46.7 0.0 2.8e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG15151.1 - 6e-11 42.3 0.0 7.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG15151.1 - 8.4e-06 25.6 0.0 1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKG15151.1 - 0.0027 17.5 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG15151.1 - 0.0042 16.8 0.0 0.011 15.4 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EKG15151.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EKG15151.1 - 0.092 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1612 PF07756.7 EKG15152.1 - 0.073 13.1 0.0 0.097 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) MFS_1 PF07690.11 EKG15153.1 - 4.3e-14 51.9 15.9 2.2e-10 39.7 4.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15153.1 - 1.2e-07 30.7 8.3 0.0027 16.3 0.3 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter COesterase PF00135.23 EKG15154.1 - 4.1e-08 32.4 0.0 4.4e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family PRA-PH PF01503.12 EKG15154.1 - 0.072 13.3 0.1 0.24 11.7 0.1 1.8 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DAO PF01266.19 EKG15155.1 - 0.012 14.5 0.0 0.012 14.4 0.0 1.0 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF3657 PF12394.3 EKG15155.1 - 0.085 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3657) TPP_enzyme_N PF02776.13 EKG15156.1 - 2.7e-37 127.8 0.3 8.3e-37 126.3 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EKG15156.1 - 4e-19 68.7 0.0 9.4e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EKG15156.1 - 1e-17 64.0 0.0 4.8e-16 58.6 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EKG15156.1 - 0.19 10.6 0.0 0.75 8.6 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Aminotran_1_2 PF00155.16 EKG15157.1 - 5.5e-17 61.7 0.0 7.8e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EKG15157.1 - 0.0035 16.4 0.0 0.16 10.9 0.0 2.3 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family CLTH PF10607.4 EKG15158.1 - 0.03 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Pkinase PF00069.20 EKG15159.1 - 1.2e-53 181.9 0.0 1.8e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG15159.1 - 1.2e-27 96.6 0.0 2.2e-26 92.4 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG15159.1 - 0.0038 16.2 0.0 0.0078 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FAD_binding_1 PF00667.15 EKG15160.1 - 3.2e-45 154.2 0.0 4.9e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EKG15160.1 - 1.4e-09 38.4 0.0 3.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain BTB PF00651.26 EKG15161.1 - 9.1e-12 44.9 0.0 8.9e-11 41.7 0.0 2.5 2 1 0 2 2 2 1 BTB/POZ domain HATPase_c_3 PF13589.1 EKG15164.1 - 0.00045 19.8 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ICAT PF06384.6 EKG15164.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT DASH_Ask1 PF08655.5 EKG15164.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 TPPII_N PF12583.3 EKG15165.1 - 0.16 12.0 0.2 0.38 10.8 0.1 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DinI PF06183.8 EKG15166.1 - 0.031 14.2 0.1 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 DinI-like family RINGv PF12906.2 EKG15167.1 - 2.9e-16 59.2 9.5 5e-16 58.4 6.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EKG15167.1 - 0.071 12.9 8.2 0.13 12.1 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.1 EKG15167.1 - 0.11 12.2 5.3 0.18 11.5 3.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EKG15167.1 - 3.7 7.2 6.9 7.4 6.2 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Apolipoprotein PF01442.13 EKG15168.1 - 0.0022 17.5 29.1 0.022 14.3 0.8 6.6 6 1 1 7 7 7 4 Apolipoprotein A1/A4/E domain Glyco_hydro_17 PF00332.13 EKG15171.1 - 4.7e-11 42.2 1.4 1.6e-07 30.7 1.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Zn_peptidase PF04228.8 EKG15171.1 - 0.051 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF4519 PF15012.1 EKG15171.1 - 0.21 11.5 0.9 0.39 10.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) AMP-binding PF00501.23 EKG15173.1 - 2.4e-84 283.1 0.0 5.4e-84 281.9 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EKG15173.1 - 3.2e-74 249.6 0.0 7.3e-74 248.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG15173.1 - 4e-57 192.7 1.7 6.4e-57 192.1 0.3 2.1 2 0 0 2 2 1 1 KR domain Acyl_transf_1 PF00698.16 EKG15173.1 - 3.9e-52 177.5 0.0 1.1e-51 176.1 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EKG15173.1 - 9.8e-49 166.0 1.6 2e-48 165.0 1.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EKG15173.1 - 1.6e-47 161.8 0.0 2.9e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 EKG15173.1 - 4.5e-47 160.0 0.1 5.2e-46 156.5 0.1 2.9 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG15173.1 - 2e-31 108.2 0.0 5.8e-31 106.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EKG15173.1 - 1.8e-18 66.8 0.0 7.6e-18 64.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 EKG15173.1 - 4.1e-18 65.4 0.0 6.6e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 EKG15173.1 - 5.4e-17 61.5 0.0 3.2e-16 59.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Methyltransf_23 PF13489.1 EKG15173.1 - 3.1e-15 56.2 0.0 1.2e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15173.1 - 2.9e-11 43.1 0.0 7.8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EKG15173.1 - 6.8e-11 42.3 0.0 1.8e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 EKG15173.1 - 1e-09 38.7 0.0 3.9e-09 36.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EKG15173.1 - 9e-09 35.1 0.0 7.3e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_18 PF12847.2 EKG15173.1 - 2.4e-08 34.5 0.0 1.3e-07 32.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG15173.1 - 6.7e-06 26.3 0.0 2.9e-05 24.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EKG15173.1 - 6.5e-05 21.9 0.0 0.00012 21.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 EKG15173.1 - 0.00021 20.5 0.0 0.00043 19.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EKG15173.1 - 0.0015 17.6 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 EKG15173.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.4 EKG15173.1 - 0.015 14.7 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase 3Beta_HSD PF01073.14 EKG15173.1 - 0.32 9.6 0.0 13 4.4 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Gcd10p PF04189.8 EKG15173.1 - 3.8 6.5 0.1 7.1 5.6 0.0 1.3 1 0 0 1 1 1 0 Gcd10p family AATase PF07247.7 EKG15173.1 - 7.6 4.9 0.1 33 2.8 0.0 1.9 3 0 0 3 3 3 0 Alcohol acetyltransferase ADH_zinc_N PF00107.21 EKG15174.1 - 1.5e-08 34.2 0.1 4.4e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG15174.1 - 1.2e-07 31.4 0.1 3e-05 23.7 0.0 2.6 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EKG15175.1 - 0.07 11.6 0.0 0.071 11.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 AMP-binding PF00501.23 EKG15176.1 - 8.2e-80 268.2 0.1 1.4e-79 267.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EKG15176.1 - 1.2e-73 247.7 0.0 3e-73 246.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG15176.1 - 1e-50 171.8 0.1 5.3e-48 163.0 0.0 3.0 2 1 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EKG15176.1 - 3.6e-50 171.0 0.3 1.3e-49 169.2 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EKG15176.1 - 2.7e-49 167.9 0.0 6.4e-49 166.7 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EKG15176.1 - 2.6e-42 144.5 1.1 6e-38 130.3 0.0 3.7 4 0 0 4 4 2 2 short chain dehydrogenase Condensation PF00668.15 EKG15176.1 - 3.3e-40 137.8 0.0 7.1e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EKG15176.1 - 1.5e-30 105.4 0.7 3.9e-30 104.1 0.0 2.1 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EKG15176.1 - 8e-27 93.7 0.0 1.8e-26 92.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EKG15176.1 - 1.4e-18 66.8 0.4 6.1e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EKG15176.1 - 2e-18 66.7 0.0 8.3e-18 64.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15176.1 - 8.7e-12 45.3 0.0 3.3e-11 43.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EKG15176.1 - 1.9e-11 43.8 0.0 1.3e-09 37.8 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 EKG15176.1 - 9.8e-11 41.8 0.0 3.6e-10 40.0 0.0 2.1 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_23 PF13489.1 EKG15176.1 - 1.3e-10 41.2 0.0 3.2e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15176.1 - 2.5e-10 40.9 0.0 2.5e-08 34.4 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15176.1 - 2e-09 37.2 0.0 7.4e-09 35.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 EKG15176.1 - 1.6e-06 27.2 0.0 4.1e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EKG15176.1 - 5.2e-06 25.7 0.0 1.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EKG15176.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Semialdhyde_dh PF01118.19 EKG15176.1 - 0.026 14.7 0.0 0.57 10.5 0.0 2.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Borrelia_P83 PF05262.6 EKG15176.1 - 0.16 10.2 3.8 0.25 9.5 2.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RrnaAD PF00398.15 EKG15176.1 - 0.7 8.8 0.0 2.2 7.2 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Post_transc_reg PF13797.1 EKG15176.1 - 0.71 9.5 0.0 1.5 8.5 0.0 1.4 1 0 0 1 1 1 0 Post-transcriptional regulator CAF-1_p150 PF11600.3 EKG15176.1 - 2.5 7.4 18.3 4.3 6.6 12.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NARP1 PF12569.3 EKG15176.1 - 6.3 5.4 7.3 12 4.5 5.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AATase PF07247.7 EKG15176.1 - 7.3 5.0 0.0 13 4.1 0.0 1.3 1 0 0 1 1 1 0 Alcohol acetyltransferase Ycf1 PF05758.7 EKG15176.1 - 8 4.0 1.9 12 3.4 1.3 1.1 1 0 0 1 1 1 0 Ycf1 CT47 PF15623.1 EKG15176.1 - 8.2 6.0 14.4 19 4.8 10.0 1.5 1 0 0 1 1 1 0 Cancer/testis gene family 47 Fungal_trans PF04082.13 EKG15178.1 - 1.1e-14 53.9 0.1 2.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG15179.1 - 6.2e-47 160.0 42.7 6.2e-47 160.0 29.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15179.1 - 1.2e-10 40.5 27.8 9.3e-10 37.6 19.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EKG15179.1 - 5e-08 31.6 2.1 8.1e-08 30.9 1.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CbtB PF09489.5 EKG15179.1 - 5.9 6.8 5.3 4.8 7.1 0.5 3.1 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Zn_clus PF00172.13 EKG15181.1 - 1.4e-06 28.1 10.0 1.4e-06 28.1 7.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EKG15182.1 - 3e-69 233.7 0.0 3.3e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EKG15183.1 - 8.9e-56 189.2 39.3 1.3e-55 188.6 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG15183.1 - 2.6e-22 78.8 32.5 4.4e-22 78.0 22.5 1.3 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.21 EKG15183.1 - 1.9e-10 40.3 0.9 3.4e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG15183.1 - 2.3e-06 27.3 2.6 3.6e-06 26.7 0.6 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain CbiQ PF02361.11 EKG15183.1 - 1.1 8.8 12.7 8.8 5.8 5.9 3.0 2 1 0 2 2 2 0 Cobalt transport protein Transp_cyt_pur PF02133.10 EKG15185.1 - 1.8e-26 92.7 33.6 9.5e-25 87.0 23.3 2.1 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Clathrin_lg_ch PF01086.12 EKG15187.1 - 8.9e-55 186.0 0.1 9.7e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.8 EKG15188.1 - 2.6e-20 72.4 0.4 5.5e-20 71.3 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 EKG15188.1 - 0.002 17.6 0.0 0.004 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) CTK3 PF12243.3 EKG15188.1 - 0.037 13.6 0.1 0.087 12.4 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Ins_P5_2-kin PF06090.7 EKG15189.1 - 6.2e-45 153.5 0.0 8.6e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF77 PF01910.12 EKG15190.1 - 7.5e-30 102.4 0.0 8.6e-30 102.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 PPR_3 PF13812.1 EKG15191.1 - 0.0082 16.3 0.1 17 6.0 0.0 4.0 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.15 EKG15191.1 - 0.034 14.1 0.0 22 5.3 0.0 3.7 3 0 0 3 3 3 0 PPR repeat PPR_2 PF13041.1 EKG15191.1 - 0.054 13.4 0.0 19 5.3 0.0 3.5 3 0 0 3 3 3 0 PPR repeat family COX7a PF02238.10 EKG15192.1 - 0.0092 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa Pyrid_oxidase_2 PF13883.1 EKG15192.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Sugar_tr PF00083.19 EKG15193.1 - 2.8e-72 243.7 24.9 3.5e-72 243.4 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15193.1 - 8.8e-27 93.7 29.6 1.9e-26 92.6 20.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG15193.1 - 1.3e-06 26.9 2.4 2.3e-06 26.1 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2553 PF10830.3 EKG15193.1 - 0.17 12.4 0.0 19 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) BetaGal_dom4_5 PF13364.1 EKG15194.1 - 0.011 16.0 0.2 0.034 14.4 0.1 1.9 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain DUF2868 PF11067.3 EKG15195.1 - 0.039 13.0 0.5 0.039 13.0 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2868) Pkinase PF00069.20 EKG15196.1 - 2.2e-41 141.7 0.0 2.7e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG15196.1 - 2e-19 69.6 0.0 2.6e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG15196.1 - 0.082 11.8 0.1 0.2 10.6 0.1 1.7 1 1 0 1 1 1 0 Kinase-like DUF4632 PF15451.1 EKG15197.1 - 0.061 13.2 1.2 0.061 13.2 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4632) ACC_central PF08326.7 EKG15200.1 - 3.3e-254 845.3 0.0 4.1e-254 845.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EKG15200.1 - 1.4e-181 604.1 0.0 2e-181 603.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EKG15200.1 - 3.8e-53 179.9 0.0 8.7e-53 178.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EKG15200.1 - 2.2e-24 85.6 0.1 4.1e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EKG15200.1 - 8.7e-22 77.1 0.0 8.3e-20 70.7 0.0 3.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EKG15200.1 - 8.1e-16 57.4 0.1 1.8e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EKG15200.1 - 7.6e-10 38.8 0.0 2.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG15200.1 - 4.1e-07 29.0 0.0 0.031 13.0 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EKG15200.1 - 1.9e-05 24.1 0.0 5.4e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EKG15200.1 - 0.0054 16.6 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EKG15200.1 - 0.11 12.1 0.0 0.31 10.7 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like RimK PF08443.6 EKG15200.1 - 0.14 11.5 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Methyltransf_23 PF13489.1 EKG15203.1 - 2.5e-19 69.5 0.0 3.9e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15203.1 - 8.6e-09 35.9 0.0 1.4e-07 32.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15203.1 - 1.8e-08 34.1 0.0 2.5e-07 30.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15203.1 - 9.6e-07 29.2 0.0 1.8e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG15203.1 - 1.6e-06 28.4 0.0 3.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG15203.1 - 2.5e-06 27.8 0.0 2.1e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG15203.1 - 0.00067 19.6 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EKG15203.1 - 0.0025 17.2 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EKG15203.1 - 0.0027 17.0 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EKG15203.1 - 0.0029 16.7 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EKG15203.1 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EKG15203.1 - 0.012 14.6 0.6 0.032 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase CopK PF11525.3 EKG15203.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein K Methyltransf_2 PF00891.13 EKG15203.1 - 0.041 13.0 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EKG15203.1 - 0.079 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase OST-HTH PF12872.2 EKG15203.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain AAA_23 PF13476.1 EKG15206.1 - 0.00073 19.9 0.0 0.0068 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG15206.1 - 0.002 18.9 0.0 0.0049 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKG15206.1 - 0.0034 16.8 0.1 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 EKG15206.1 - 0.0053 17.0 0.0 0.035 14.4 0.0 2.2 2 1 0 2 2 2 1 ABC transporter NACHT PF05729.7 EKG15206.1 - 0.0068 16.0 0.1 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 EKG15206.1 - 0.015 14.8 0.3 0.048 13.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG15206.1 - 0.019 15.1 0.0 0.067 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EKG15206.1 - 0.035 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 EKG15206.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EKG15206.1 - 0.069 13.0 0.4 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EKG15206.1 - 0.086 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EKG15206.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKG15206.1 - 0.12 11.5 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Abhydrolase_6 PF12697.2 EKG15210.1 - 4e-17 62.8 0.1 4.5e-17 62.6 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG15210.1 - 2.2e-08 33.9 0.1 2.4e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EKG15210.1 - 0.006 16.0 0.0 0.0076 15.6 0.0 1.1 1 0 0 1 1 1 1 PE-PPE domain DUF900 PF05990.7 EKG15210.1 - 0.019 14.3 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 EKG15210.1 - 0.058 12.9 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EKG15210.1 - 0.098 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF1100 PF06500.6 EKG15210.1 - 0.12 10.9 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) SYF2 PF08231.7 EKG15211.1 - 4.2e-54 182.8 15.4 4.2e-54 182.8 10.7 1.6 2 0 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 EKG15211.1 - 2 8.3 10.8 6.4 6.7 3.7 3.1 1 1 1 2 2 2 0 ARD/ARD' family Methyltransf_23 PF13489.1 EKG15214.1 - 0.057 13.1 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain KR PF08659.5 EKG15215.1 - 4.7e-24 85.0 1.6 7.5e-24 84.3 0.3 1.9 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.21 EKG15215.1 - 5.6e-23 80.9 0.6 1.7e-22 79.3 0.0 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.20 EKG15215.1 - 3.5e-21 75.8 0.3 4.3e-20 72.2 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EKG15215.1 - 1.9e-15 57.8 0.0 4.9e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG15215.1 - 2.1e-10 40.3 0.6 5.1e-10 39.0 0.1 2.0 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.1 EKG15215.1 - 0.00066 19.5 0.0 0.084 12.6 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 EKG15215.1 - 0.0058 17.0 0.5 3.4 8.1 0.1 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EKG15215.1 - 0.014 15.3 1.5 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 EKG15215.1 - 0.026 14.0 0.1 0.065 12.8 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Saccharop_dh PF03435.13 EKG15215.1 - 0.044 12.7 0.1 0.086 11.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Creatininase PF02633.9 EKG15215.1 - 0.063 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Creatinine amidohydrolase NmrA PF05368.8 EKG15215.1 - 0.071 12.3 0.6 0.72 9.0 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 EKG15215.1 - 0.071 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 EKG15215.1 - 0.16 11.0 1.7 1.3 8.0 0.0 2.8 3 1 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 EKG15216.1 - 3.2e-74 249.6 0.0 6.5e-74 248.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG15216.1 - 9.1e-52 176.3 1.1 3.1e-51 174.5 0.8 1.9 1 1 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EKG15216.1 - 2.8e-48 164.6 3.8 6e-48 163.5 2.6 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EKG15216.1 - 2.8e-36 123.9 0.4 7.5e-36 122.5 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EKG15216.1 - 5.9e-19 68.3 0.0 1.6e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG15216.1 - 2.2e-11 43.7 0.0 5.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15216.1 - 9.1e-11 41.5 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15216.1 - 8.8e-10 38.9 0.0 2.4e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15216.1 - 5.4e-09 36.6 0.1 1.1e-07 32.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG15216.1 - 9.1e-08 31.4 0.0 1.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EKG15216.1 - 1.7e-05 24.8 0.2 7.4e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EKG15216.1 - 0.0016 17.5 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_24 PF13578.1 EKG15216.1 - 0.02 15.7 0.0 0.12 13.1 0.0 2.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EKG15216.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 EKG15216.1 - 0.3 10.0 0.0 20 4.0 0.0 2.4 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family FSH1 PF03959.8 EKG15218.1 - 0.09 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Glyco_hydro_65m PF03632.10 EKG15220.1 - 1.3e-52 178.7 1.3 2.9e-51 174.3 0.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EKG15220.1 - 0.032 13.5 0.1 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain p450 PF00067.17 EKG15221.1 - 5.8e-54 183.3 0.0 9.7e-54 182.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UDPGT PF00201.13 EKG15221.1 - 7.4e-05 21.4 0.0 0.00011 20.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase YEATS PF03366.11 EKG15222.1 - 1e-24 86.0 0.0 2e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 YEATS family NAD_binding_10 PF13460.1 EKG15223.1 - 0.021 14.8 0.0 0.17 11.8 0.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding Ribonuclease PF00545.15 EKG15224.1 - 4.8e-14 52.1 0.0 6.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 ribonuclease WD40 PF00400.27 EKG15225.1 - 4.4e-31 105.6 4.9 1.4e-06 27.9 0.0 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat PD40 PF07676.7 EKG15225.1 - 0.048 13.3 0.3 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 EKG15225.1 - 0.19 11.2 0.0 25 4.4 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.23 EKG15226.1 - 8.7e-81 271.4 0.0 1.1e-80 271.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG15226.1 - 2.7e-13 50.6 0.3 8.1e-13 49.1 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1343 PF07075.6 EKG15226.1 - 0.18 10.5 0.0 0.33 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) 2OG-FeII_Oxy_2 PF13532.1 EKG15227.1 - 3.5e-19 69.4 0.0 6.6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acyl-CoA_dh_1 PF00441.19 EKG15228.1 - 9.5e-39 132.8 0.6 1.6e-38 132.1 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG15228.1 - 1.6e-34 118.9 0.3 3.2e-34 117.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EKG15228.1 - 2.2e-20 71.9 0.1 4.8e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EKG15228.1 - 1.9e-14 54.0 0.1 3.8e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EKG15228.1 - 0.0002 20.8 0.5 0.00085 18.7 0.4 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF3635 PF12330.3 EKG15229.1 - 1.9e-10 40.6 1.1 2.5e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF3635) KdpC PF02669.10 EKG15229.1 - 0.094 12.4 0.3 0.32 10.6 0.1 1.9 3 0 0 3 3 3 0 K+-transporting ATPase, c chain Spc7 PF08317.6 EKG15230.1 - 0.00013 20.7 50.1 0.0015 17.2 2.2 4.1 2 1 2 4 4 4 2 Spc7 kinetochore protein EzrA PF06160.7 EKG15230.1 - 0.0012 17.0 27.5 0.0012 17.0 19.1 2.8 2 1 1 3 3 3 1 Septation ring formation regulator, EzrA AAA_13 PF13166.1 EKG15230.1 - 0.0021 16.5 24.3 0.0021 16.5 16.8 4.1 2 2 2 5 5 5 2 AAA domain Reo_sigmaC PF04582.7 EKG15230.1 - 0.0049 16.0 1.2 0.0049 16.0 0.9 2.5 2 1 1 3 3 3 1 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EKG15230.1 - 0.0058 16.3 19.7 0.0058 16.3 13.7 5.1 3 1 1 4 4 4 1 TPR/MLP1/MLP2-like protein SNARE PF05739.14 EKG15230.1 - 0.2 11.3 10.9 0.58 9.8 0.2 3.7 3 0 0 3 3 3 0 SNARE domain ERM PF00769.14 EKG15230.1 - 0.34 10.4 59.6 0.066 12.7 0.3 4.2 3 1 1 4 4 4 0 Ezrin/radixin/moesin family GAS PF13851.1 EKG15230.1 - 0.56 9.3 56.3 1.1 8.3 14.8 4.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.7 EKG15230.1 - 1.1 9.5 17.1 4 7.7 0.1 5.3 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Cortex-I_coil PF09304.5 EKG15230.1 - 2.5 8.1 53.1 1.4 8.9 10.6 4.8 2 1 2 4 4 4 0 Cortexillin I, coiled coil Fez1 PF06818.10 EKG15230.1 - 9.7 6.1 48.9 3.3 7.6 0.5 4.4 3 1 1 4 4 4 0 Fez1 AMP-binding PF00501.23 EKG15231.1 - 1.3e-89 300.5 0.0 1.6e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG15231.1 - 5.3e-18 65.7 0.5 1.6e-17 64.1 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pkinase PF00069.20 EKG15232.1 - 1.5e-66 224.1 0.0 2.1e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG15232.1 - 9e-34 116.7 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG15232.1 - 0.00018 21.3 0.1 0.036 13.7 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG15232.1 - 0.031 13.2 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 EKG15232.1 - 0.045 12.5 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ATP-synt_C PF00137.16 EKG15233.1 - 1.2e-25 89.1 28.3 2.2e-14 53.0 4.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 EKG15234.1 - 1.1e-84 284.0 0.1 1.3e-83 280.6 0.0 2.1 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EKG15234.1 - 2.1e-49 166.9 1.8 4.3e-49 165.9 1.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EKG15234.1 - 1.6e-39 135.6 0.1 3.1e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EKG15234.1 - 1.2e-11 44.2 0.2 3.3e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) F-box-like_2 PF13013.1 EKG15235.1 - 0.019 14.6 0.7 0.035 13.8 0.5 1.5 1 1 0 1 1 1 0 F-box-like domain MCM PF00493.18 EKG15235.1 - 0.15 10.7 0.1 0.16 10.7 0.1 1.0 1 0 0 1 1 1 0 MCM2/3/5 family BTB PF00651.26 EKG15236.1 - 6.7e-10 38.9 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Zn-ribbon_8 PF09723.5 EKG15236.1 - 0.0047 16.8 0.2 0.0086 16.0 0.1 1.4 1 0 0 1 1 1 1 Zinc ribbon domain SprT-like PF10263.4 EKG15236.1 - 0.075 12.6 0.2 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 SprT-like family p450 PF00067.17 EKG15238.1 - 1.2e-77 261.4 0.0 1.6e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EKG15239.1 - 3.7e-11 42.6 0.3 6e-10 38.7 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EKG15240.1 - 1.6e-31 109.3 25.8 1.6e-31 109.3 17.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily peroxidase PF00141.18 EKG15241.1 - 1.1e-88 296.6 0.0 4.6e-47 160.4 0.0 2.1 2 0 0 2 2 2 2 Peroxidase RabGAP-TBC PF00566.13 EKG15242.1 - 3.7e-48 163.8 0.1 6.4e-48 163.0 0.1 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EKG15242.1 - 5.3e-07 29.6 0.9 5.6e-06 26.3 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EKG15242.1 - 4e-05 23.1 5.8 0.0031 17.2 0.5 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EKG15242.1 - 0.00011 21.2 1.3 0.051 12.8 0.6 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 EKG15242.1 - 0.013 14.8 1.2 0.045 13.1 0.8 2.0 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 EKG15242.1 - 0.018 14.6 0.2 10 5.7 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain pair GRAM PF02893.15 EKG15242.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 GRAM domain CDC37_N PF03234.9 EKG15243.1 - 1.4e-59 201.4 6.5 1.4e-59 201.4 4.5 2.5 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EKG15243.1 - 1e-49 168.3 0.4 1e-49 168.3 0.2 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EKG15243.1 - 3.7e-24 84.4 0.4 1.3e-23 82.7 0.3 1.9 1 0 0 1 1 1 1 Cdc37 C terminal domain ABC_membrane PF00664.18 EKG15244.1 - 5.7e-45 153.8 11.4 7.4e-45 153.4 7.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EKG15244.1 - 3.5e-35 121.2 0.0 1.1e-34 119.6 0.0 1.9 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EKG15244.1 - 0.00016 21.0 0.0 0.00036 19.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EKG15244.1 - 0.0029 17.7 0.2 0.028 14.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG15244.1 - 0.0063 17.3 0.0 0.033 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG15244.1 - 0.0071 16.3 0.3 0.03 14.3 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EKG15244.1 - 0.0074 15.7 0.3 0.039 13.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EKG15244.1 - 0.011 15.8 0.0 0.08 13.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EKG15244.1 - 0.012 15.5 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EKG15244.1 - 0.037 13.5 0.1 0.54 9.7 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.1 EKG15244.1 - 0.065 12.7 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 EKG15244.1 - 0.09 12.7 3.2 0.11 12.4 0.3 2.6 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit YccJ PF13993.1 EKG15244.1 - 0.11 12.5 1.3 12 6.0 0.0 2.5 2 0 0 2 2 2 0 YccJ-like protein TMA7 PF09072.5 EKG15244.1 - 0.15 12.5 0.6 0.36 11.3 0.4 1.6 1 0 0 1 1 1 0 Translation machinery associated TMA7 Cupin_2 PF07883.6 EKG15245.1 - 1.6e-16 59.5 0.4 1.6e-16 59.5 0.3 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EKG15245.1 - 3.3e-06 26.6 0.0 5.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EKG15245.1 - 3.6e-05 23.4 0.0 5.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_6 PF12852.2 EKG15245.1 - 0.00012 21.7 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EKG15245.1 - 0.0014 18.5 0.1 0.003 17.5 0.0 1.5 1 1 0 1 1 1 1 ARD/ARD' family Cupin_3 PF05899.7 EKG15245.1 - 0.002 17.4 0.1 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) GPI PF06560.6 EKG15245.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) MannoseP_isomer PF01050.13 EKG15245.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase JmjC PF02373.17 EKG15245.1 - 0.096 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase adh_short_C2 PF13561.1 EKG15246.1 - 1.1e-28 100.6 0.1 1.4e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG15246.1 - 2.4e-21 76.3 0.7 4.1e-21 75.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15246.1 - 2.8e-13 49.9 0.3 5e-13 49.1 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EKG15246.1 - 0.0014 18.2 0.2 0.0064 16.1 0.2 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EKG15246.1 - 0.0043 16.5 1.2 0.034 13.5 0.9 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EKG15246.1 - 0.077 12.8 0.3 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Exo_endo_phos PF03372.18 EKG15247.1 - 7.7e-21 75.1 0.9 1.1e-20 74.6 0.6 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.19 EKG15248.1 - 5.2e-131 437.3 25.6 6e-131 437.1 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15248.1 - 6.7e-26 90.8 48.2 5.9e-24 84.4 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG15248.1 - 3.4e-08 32.3 28.8 7.6e-07 27.8 7.7 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EKG15248.1 - 0.029 12.5 9.1 0.015 13.5 2.5 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EKG15248.1 - 0.063 13.0 0.1 0.063 13.0 0.0 3.8 3 0 0 3 3 3 0 MFS_1 like family DUF3154 PF11351.3 EKG15248.1 - 0.46 10.2 5.9 1.7 8.3 2.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3154) Phage_holin_2 PF04550.7 EKG15248.1 - 3 7.9 7.1 6.7 6.8 3.6 2.5 3 0 0 3 3 3 0 Phage holin family 2 Bot1p PF12298.3 EKG15249.1 - 9.9e-50 168.8 3.5 1.6e-49 168.1 2.4 1.4 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein RRM_1 PF00076.17 EKG15250.1 - 3.3e-16 58.6 0.1 9.1e-13 47.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG15250.1 - 7.9e-13 48.1 0.1 1.4e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3605 PF12239.3 EKG15251.1 - 7.5e-52 175.3 0.0 9e-52 175.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) NAD_binding_1 PF00175.16 EKG15252.1 - 7e-28 97.3 0.0 8.4e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EKG15252.1 - 3.5e-06 26.9 0.0 0.0045 16.9 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain DUF2052 PF09747.4 EKG15253.1 - 2.9e-32 112.0 15.3 3.2e-31 108.6 10.6 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Methyltransf_26 PF13659.1 EKG15254.1 - 4.7e-08 33.0 0.1 1.2e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 EKG15254.1 - 4.8e-08 32.2 0.0 7.3e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EKG15254.1 - 6.2e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EKG15254.1 - 0.047 12.7 0.1 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 EKG15254.1 - 0.048 14.1 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EKG15254.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PilJ PF13675.1 EKG15254.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3716 PF12511.3 EKG15255.1 - 0.093 12.3 2.5 0.17 11.4 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) ketoacyl-synt PF00109.21 EKG15258.1 - 4.2e-72 242.6 0.0 1.1e-71 241.3 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG15258.1 - 2.1e-52 178.4 0.1 3.9e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EKG15258.1 - 1.3e-48 165.6 9.9 3.7e-48 164.1 5.7 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EKG15258.1 - 5.4e-31 106.9 0.0 1.7e-30 105.2 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EKG15258.1 - 1.5e-08 34.4 0.2 3.6e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKG15258.1 - 8.9e-06 25.7 1.6 2.8e-05 24.1 0.2 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EKG15258.1 - 1.4e-05 25.5 0.0 4.3e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15258.1 - 0.0012 19.2 0.0 0.0038 17.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EKG15258.1 - 0.013 14.5 0.0 0.033 13.1 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EKG15258.1 - 0.025 15.1 0.0 0.13 12.8 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain DUF1788 PF08747.6 EKG15258.1 - 0.69 9.7 0.0 1.8 8.4 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF1788) Condensation PF00668.15 EKG15259.1 - 3.5e-42 144.2 0.0 6.4e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain HxxPF_rpt PF13745.1 EKG15259.1 - 1.8e-14 53.7 0.0 4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 HxxPF-repeated domain CAML PF14963.1 EKG15259.1 - 1.4 8.1 5.4 2.8 7.2 3.7 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Med3 PF11593.3 EKG15259.1 - 7.2 5.7 10.8 13 4.8 7.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NAD_binding_4 PF07993.7 EKG15260.1 - 1.7e-32 112.3 0.1 1.7e-31 109.0 0.1 2.5 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EKG15260.1 - 4e-31 107.8 0.3 5.9e-31 107.2 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EKG15260.1 - 6.6e-10 39.1 0.0 1.3e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EKG15260.1 - 1.8e-09 37.4 0.2 5.4e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family L31 PF09784.4 EKG15262.1 - 1.3e-27 95.8 0.4 2e-27 95.2 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Sugar_tr PF00083.19 EKG15262.1 - 9.4e-06 24.4 6.7 1.3e-05 24.0 4.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.19 EKG15263.1 - 1.3e-31 109.6 0.2 1.4e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15263.1 - 5.2e-08 31.9 1.7 6.4e-08 31.6 1.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sedlin_N PF04628.8 EKG15264.1 - 7.4e-43 145.5 0.0 8.6e-43 145.3 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EKG15264.1 - 6.5e-06 25.9 0.0 0.00079 19.1 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family HeLo PF14479.1 EKG15265.1 - 0.0015 18.3 4.6 0.011 15.4 0.2 2.8 2 1 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.20 EKG15265.1 - 0.002 17.3 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Hairy_orange PF07527.8 EKG15265.1 - 0.2 11.4 0.7 9.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Hairy Orange Mito_carr PF00153.22 EKG15266.1 - 5.4e-47 157.4 0.3 2.9e-15 55.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Bd3614_N PF14442.1 EKG15266.1 - 0.039 13.9 6.1 0.16 11.9 0.1 2.9 2 1 0 2 2 2 0 Bd3614-like deaminase N-terminal NUDE_C PF04880.8 EKG15267.1 - 9.3e-19 68.3 2.5 9.3e-19 68.3 1.7 4.3 3 1 0 4 4 4 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EKG15267.1 - 0.0042 17.3 5.0 0.0042 17.3 3.5 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF904) Peptidase_C10 PF01640.12 EKG15267.1 - 0.85 9.3 2.4 1.6 8.4 1.6 1.4 1 0 0 1 1 1 0 Peptidase C10 family AAA_13 PF13166.1 EKG15267.1 - 4.4 5.6 22.2 6.2 5.1 15.4 1.1 1 0 0 1 1 1 0 AAA domain ATG16 PF08614.6 EKG15267.1 - 6 6.6 33.7 0.58 9.9 16.9 2.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EKG15267.1 - 6.1 6.3 34.5 8.7 5.8 10.8 2.4 1 1 1 2 2 2 0 IncA protein polyprenyl_synt PF00348.12 EKG15268.1 - 2e-27 95.6 0.0 2.2e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase PMR5N PF14416.1 EKG15270.1 - 0.044 13.8 1.0 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 PMR5 N terminal Domain Hydrophobin_2 PF06766.6 EKG15270.1 - 0.045 13.4 0.3 0.089 12.4 0.2 1.4 1 0 0 1 1 1 0 Fungal hydrophobin CopD PF05425.8 EKG15271.1 - 0.83 9.8 6.3 0.084 13.0 0.8 1.9 2 0 0 2 2 2 0 Copper resistance protein D GMC_oxred_N PF00732.14 EKG15272.1 - 2.4e-49 168.1 0.0 3.9e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG15272.1 - 9.9e-30 103.7 0.0 2.3e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG15272.1 - 0.0069 15.2 0.0 0.015 14.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EKG15272.1 - 0.022 14.7 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EKG15274.1 - 8.6e-11 41.1 17.8 1.2e-10 40.6 12.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EKG15274.1 - 0.0006 19.3 1.1 0.0013 18.2 0.7 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EKG15274.1 - 0.0021 16.7 7.5 0.0036 15.9 5.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter AA_permease PF00324.16 EKG15275.1 - 6.9e-87 291.7 38.6 8.5e-87 291.4 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG15275.1 - 4.9e-27 94.5 40.4 5.9e-27 94.2 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AAA PF00004.24 EKG15277.1 - 2.1e-29 102.4 0.0 3.9e-15 56.2 0.0 4.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG15277.1 - 3.3e-08 33.7 1.2 0.064 13.3 0.0 5.5 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EKG15277.1 - 4.9e-07 29.3 1.0 0.02 14.6 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 EKG15277.1 - 5.6e-07 28.9 0.1 0.032 13.3 0.0 3.6 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EKG15277.1 - 3.7e-06 27.7 0.0 0.18 12.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EKG15277.1 - 2.2e-05 24.1 0.1 0.062 13.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKG15277.1 - 0.00043 20.3 2.0 0.29 11.0 0.0 3.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_11 PF13086.1 EKG15277.1 - 0.00078 19.0 3.5 2.4 7.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EKG15277.1 - 0.0014 18.0 1.2 0.15 11.4 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_28 PF13521.1 EKG15277.1 - 0.024 14.6 3.3 4.4 7.2 0.1 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EKG15277.1 - 0.031 14.4 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase VirE PF05272.6 EKG15277.1 - 0.031 13.7 0.0 0.092 12.2 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E AAA_18 PF13238.1 EKG15277.1 - 0.033 14.4 6.0 2.3 8.5 0.1 3.4 3 0 0 3 3 3 0 AAA domain Guanylate_cyc_2 PF09778.4 EKG15277.1 - 0.043 12.9 0.0 3.8 6.6 0.0 2.8 3 0 0 3 3 3 0 Guanylylate cyclase Torsin PF06309.6 EKG15277.1 - 0.078 12.8 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Torsin AAA_10 PF12846.2 EKG15277.1 - 0.12 11.7 2.6 15 4.9 0.1 4.1 4 1 0 4 4 4 0 AAA-like domain AAA_33 PF13671.1 EKG15277.1 - 0.23 11.3 10.6 0.86 9.4 0.0 3.7 5 0 0 5 5 3 0 AAA domain AAA_24 PF13479.1 EKG15277.1 - 0.26 10.8 8.7 1.8 8.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain Glyoxalase_2 PF12681.2 EKG15278.1 - 0.00011 22.7 1.0 0.00027 21.5 0.7 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain NAD_binding_8 PF13450.1 EKG15279.1 - 0.00039 20.3 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG15279.1 - 0.0015 18.5 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG15279.1 - 0.018 14.8 0.0 0.043 13.5 0.0 1.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EKG15279.1 - 0.059 12.2 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EKG15279.1 - 0.089 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EKG15279.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Reprolysin_2 PF13574.1 EKG15282.1 - 1.8e-05 24.8 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EKG15282.1 - 6.8e-05 22.6 0.2 0.00016 21.4 0.1 1.7 1 1 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.1 EKG15282.1 - 0.00063 19.3 0.0 0.00088 18.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EKG15282.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.8 EKG15282.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EKG15282.1 - 0.011 16.3 0.1 0.02 15.4 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EKG15282.1 - 0.022 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 EKG15282.1 - 0.033 13.0 0.1 0.052 12.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 HdeA PF06411.6 EKG15285.1 - 0.0059 16.5 0.2 0.0088 15.9 0.2 1.3 1 0 0 1 1 1 1 HdeA/HdeB family Imm5 PF14423.1 EKG15286.1 - 0.013 15.0 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Immunity protein Imm5 APG6 PF04111.7 EKG15286.1 - 0.047 12.7 2.1 0.053 12.5 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CALCOCO1 PF07888.6 EKG15286.1 - 0.054 11.7 1.9 0.063 11.5 1.3 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like CCDC155 PF14662.1 EKG15286.1 - 0.054 13.0 2.5 0.068 12.7 1.8 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 PilJ PF13675.1 EKG15286.1 - 0.17 12.2 2.9 0.23 11.8 2.0 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term adh_short PF00106.20 EKG15288.1 - 1.9e-11 44.1 1.0 3.7e-11 43.2 0.1 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG15288.1 - 0.00029 20.5 0.2 0.00046 19.9 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG15288.1 - 0.02 14.6 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Sporozoite_P67 PF05642.6 EKG15288.1 - 0.11 10.3 0.0 0.15 9.8 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Retrotrans_gag PF03732.12 EKG15290.1 - 1.6e-08 34.4 0.5 1.9e-08 34.2 0.3 1.1 1 0 0 1 1 1 1 Retrotransposon gag protein AT_hook PF02178.14 EKG15291.1 - 3.6 7.5 7.8 61 3.7 3.4 2.9 2 0 0 2 2 2 0 AT hook motif NmrA PF05368.8 EKG15292.1 - 2.8e-18 66.0 0.0 3.3e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG15292.1 - 5.2e-13 49.3 0.0 9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG15292.1 - 2.8e-08 33.4 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG15292.1 - 1.6e-05 23.7 0.0 2.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EKG15292.1 - 5.2e-05 22.4 0.1 7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EKG15293.1 - 6.8e-09 35.8 0.0 1.3e-08 34.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15293.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 KR domain Fungal_trans_2 PF11951.3 EKG15294.1 - 6.2e-09 34.9 0.5 9.9e-09 34.2 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 EKG15299.1 - 2e-20 73.2 0.1 2.9e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG15299.1 - 6.1e-08 32.1 0.0 5.1e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 EKG15299.1 - 5.2e-06 26.0 0.0 8.2e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EKG15299.1 - 3.1e-05 23.7 0.0 6.1e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EKG15299.1 - 3.2e-05 23.3 0.2 9.6e-05 21.7 0.2 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase COesterase PF00135.23 EKG15299.1 - 8.6e-05 21.4 0.0 0.00022 20.0 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 EKG15299.1 - 0.00041 19.3 0.0 0.0008 18.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EKG15299.1 - 0.00061 19.7 6.8 0.00086 19.2 4.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG15299.1 - 0.01 15.3 0.6 0.029 13.9 0.4 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 EKG15299.1 - 0.023 13.1 0.0 0.058 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 EKG15300.1 - 1.1e-14 54.0 0.4 2.2e-14 52.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG15300.1 - 1.1e-08 34.7 11.1 1.1e-08 34.7 7.7 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 EKG15301.1 - 3e-31 107.7 1.3 4.7e-31 107.1 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain Beta-lactamase PF00144.19 EKG15302.1 - 2.7e-46 158.1 0.0 3.7e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EKG15302.1 - 0.025 13.8 0.0 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase p450 PF00067.17 EKG15303.1 - 2.9e-58 197.5 0.0 3.6e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3924 PF13062.1 EKG15304.1 - 0.14 12.0 0.1 0.26 11.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) Radical_SAM PF04055.16 EKG15305.1 - 2.4e-17 63.5 0.1 6.4e-17 62.2 0.1 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EKG15305.1 - 6.6e-08 32.7 0.1 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EKG15305.1 - 1.7e-05 24.8 0.0 3.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Tat PF00539.13 EKG15305.1 - 0.018 14.6 0.3 0.51 9.9 0.1 2.4 2 0 0 2 2 2 0 Transactivating regulatory protein (Tat) PHD PF00628.24 EKG15305.1 - 0.87 9.3 5.3 0.95 9.2 0.7 2.7 2 0 0 2 2 2 0 PHD-finger 7kD_coat PF02495.12 EKG15305.1 - 0.93 8.9 3.8 42 3.7 0.0 2.4 2 0 0 2 2 2 0 7kD viral coat protein ADK PF00406.17 EKG15306.1 - 1.7e-09 37.6 0.0 1.3e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Adenylate kinase HEAT_2 PF13646.1 EKG15307.1 - 0.11 12.8 0.1 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 HEAT repeats Clostridium_P47 PF06597.6 EKG15308.1 - 6.9e-08 31.4 3.9 9.4e-08 30.9 2.7 1.2 1 0 0 1 1 1 1 Clostridium P-47 protein FPN1 PF06963.7 EKG15308.1 - 0.023 13.0 0.0 0.035 12.5 0.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Arif-1 PF06770.6 EKG15308.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Aldo_ket_red PF00248.16 EKG15313.1 - 1.4e-57 194.7 0.0 1.6e-57 194.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DOMON PF03351.12 EKG15315.1 - 0.0017 18.2 0.4 0.0034 17.3 0.3 1.4 1 0 0 1 1 1 1 DOMON domain PepSY_TM_1 PF13172.1 EKG15315.1 - 0.065 13.0 7.4 1.5 8.6 2.1 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix DUF2427 PF10348.4 EKG15315.1 - 0.29 10.7 7.7 0.97 9.0 5.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) DUF1232 PF06803.7 EKG15315.1 - 0.31 10.5 2.5 0.91 9.0 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Ppx-GppA PF02541.11 EKG15316.1 - 5.1e-37 127.6 0.0 1.8e-36 125.8 0.0 1.7 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 EKG15316.1 - 0.24 9.8 0.1 0.4 9.1 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Retrotrans_gag PF03732.12 EKG15317.1 - 6.1e-09 35.8 1.0 1.5e-08 34.5 0.3 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein Imm5 PF14423.1 EKG15317.1 - 0.028 14.0 0.1 0.044 13.4 0.1 1.3 1 0 0 1 1 1 0 Immunity protein Imm5 Pmp3 PF01679.12 EKG15318.1 - 3.4e-16 58.6 3.4 5.3e-16 58.0 2.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ABC_tran PF00005.22 EKG15321.1 - 3.9e-33 114.6 0.0 1e-32 113.3 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EKG15321.1 - 2.9e-23 82.6 13.7 2.9e-23 82.6 9.5 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.1 EKG15321.1 - 3e-06 27.3 0.0 7.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EKG15321.1 - 1e-05 24.9 0.2 0.0018 17.5 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG15321.1 - 0.00042 20.3 0.5 0.0057 16.6 0.0 2.7 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EKG15321.1 - 0.001 18.1 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EKG15321.1 - 0.0019 17.6 1.7 0.0042 16.5 0.3 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EKG15321.1 - 0.0036 16.5 0.0 0.0082 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG15321.1 - 0.0094 16.7 0.0 0.033 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG15321.1 - 0.011 15.8 0.0 0.041 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EKG15321.1 - 0.015 15.6 0.4 0.049 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EKG15321.1 - 0.024 14.9 0.0 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EKG15321.1 - 0.028 14.2 0.8 0.059 13.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EKG15321.1 - 0.077 12.9 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3112 PF11309.3 EKG15321.1 - 4 7.2 17.2 0.28 10.9 0.5 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF3112) ECH PF00378.15 EKG15323.1 - 4.8e-26 91.3 0.0 5.8e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ADH_zinc_N PF00107.21 EKG15324.1 - 7.6e-17 61.0 0.0 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG15324.1 - 3.5e-12 47.3 0.1 9e-12 46.0 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG15324.1 - 1.7e-08 34.1 0.0 4.6e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SnoaL_4 PF13577.1 EKG15325.1 - 4.5e-24 84.7 0.2 5.6e-24 84.4 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EKG15325.1 - 0.017 15.4 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 EKG15325.1 - 0.02 15.1 0.1 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Ring_hydroxyl_B PF00866.13 EKG15325.1 - 0.12 12.0 0.1 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 Ring hydroxylating beta subunit Amidase PF01425.16 EKG15326.1 - 7.3e-76 255.7 0.0 9.8e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF4188 PF13826.1 EKG15328.1 - 1.1e-26 93.2 0.1 1.4e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EKG15328.1 - 0.0052 15.8 0.3 0.0065 15.5 0.2 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase MARVEL PF01284.18 EKG15329.1 - 0.00038 20.2 12.2 0.00097 18.9 8.4 1.9 1 1 0 1 1 1 1 Membrane-associating domain FAD_binding_4 PF01565.18 EKG15330.1 - 5.2e-19 68.1 1.7 8.8e-19 67.3 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain PS_pyruv_trans PF04230.8 EKG15331.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Shikimate_DH PF01488.15 EKG15332.1 - 6.7e-14 52.1 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 EKG15332.1 - 7.6e-06 25.8 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Saccharop_dh PF03435.13 EKG15332.1 - 0.0039 16.2 0.0 0.0048 15.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase OCD_Mu_crystall PF02423.10 EKG15332.1 - 0.018 13.8 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family ApbA PF02558.11 EKG15332.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA adh_short PF00106.20 EKG15333.1 - 0.00097 19.0 0.8 0.0015 18.4 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase TrwC PF08751.6 EKG15333.1 - 0.0039 16.6 0.0 0.005 16.3 0.0 1.1 1 0 0 1 1 1 1 TrwC relaxase adh_short_C2 PF13561.1 EKG15333.1 - 0.089 12.5 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF2236 PF09995.4 EKG15333.1 - 0.15 11.3 0.0 0.61 9.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) Shikimate_dh_N PF08501.6 EKG15336.1 - 8.5e-05 22.5 0.0 0.00016 21.6 0.0 1.4 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain MFS_1 PF07690.11 EKG15337.1 - 1.8e-17 63.1 23.6 2.2e-17 62.7 16.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG15337.1 - 0.45 8.6 9.2 0.54 8.3 6.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF1662 PF07878.6 EKG15341.1 - 0.071 12.8 0.3 0.6 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) TPR_MLP1_2 PF07926.7 EKG15341.1 - 0.12 12.1 12.3 0.21 11.3 8.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EKG15341.1 - 0.52 10.2 13.6 10 6.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin PF00804.20 EKG15341.1 - 1.5 9.0 7.8 0.66 10.1 3.0 2.1 1 1 1 2 2 2 0 Syntaxin TMF_TATA_bd PF12325.3 EKG15341.1 - 2 8.1 15.8 0.33 10.6 5.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 EKG15341.1 - 2.7 7.8 20.7 2.9 7.7 5.7 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EKG15341.1 - 3.4 8.0 11.6 0.65 10.3 1.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EKG15341.1 - 5 6.8 14.1 2.7 7.7 3.0 2.4 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Cu-oxidase_2 PF07731.9 EKG15342.1 - 1.5e-41 141.1 10.0 7.8e-38 129.1 0.2 3.5 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG15342.1 - 7.4e-38 128.9 5.9 7.2e-35 119.2 0.1 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG15342.1 - 1e-30 106.7 1.2 6.9e-28 97.5 0.5 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EKG15342.1 - 0.091 12.6 0.0 7.7 6.4 0.0 2.8 2 0 0 2 2 2 0 Cupredoxin-like domain Cu-oxidase PF00394.17 EKG15345.1 - 1.3e-16 60.9 0.0 4.8e-16 59.0 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase UEV PF05743.8 EKG15345.1 - 0.073 12.7 0.1 0.21 11.2 0.1 1.7 2 0 0 2 2 2 0 UEV domain Sugar_tr PF00083.19 EKG15347.1 - 2e-111 372.7 22.2 2.3e-111 372.5 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15347.1 - 3.4e-17 62.1 42.6 1.4e-16 60.1 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EKG15347.1 - 0.0021 16.8 1.7 0.0021 16.7 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 EKG15347.1 - 0.2 11.5 4.2 0.42 10.4 0.2 2.7 2 0 0 2 2 2 0 MFS_1 like family DUF2264 PF10022.4 EKG15348.1 - 3e-39 134.6 0.0 3.6e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) IMS PF00817.15 EKG15350.1 - 2.5e-24 85.7 0.3 6.2e-24 84.4 0.2 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EKG15350.1 - 2.6e-16 59.7 0.0 4.9e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EKG15350.1 - 0.0001 22.0 0.0 0.00043 20.1 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif Prenyltrans_1 PF13243.1 EKG15350.1 - 0.038 13.9 0.3 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 Prenyltransferase-like Glyco_hydro_3 PF00933.16 EKG15351.1 - 3.6e-91 305.2 0.0 5.3e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG15351.1 - 1.8e-55 187.9 0.3 4.6e-55 186.6 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG15351.1 - 5.7e-24 83.8 0.0 1.1e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF952 PF06108.7 EKG15352.1 - 1.1e-27 95.7 0.0 1.3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Abhydrolase_3 PF07859.8 EKG15353.1 - 3.2e-37 128.1 0.0 4.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG15353.1 - 9.8e-06 24.5 0.1 1.6e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EKG15353.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EKG15353.1 - 0.0048 16.3 0.1 0.96 8.8 0.0 2.3 2 0 0 2 2 2 2 Putative esterase DUF883 PF05957.8 EKG15353.1 - 0.14 12.5 0.3 1.2 9.5 0.0 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4643 PF15485.1 EKG15353.1 - 0.16 11.3 0.4 0.25 10.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Aldedh PF00171.17 EKG15354.1 - 1.4e-167 557.6 0.1 1.6e-167 557.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.14 EKG15355.1 - 2.2e-07 30.2 0.0 2.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG15355.1 - 0.0034 16.2 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Acetyltransf_1 PF00583.19 EKG15356.1 - 6.5e-17 61.3 0.1 1e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG15356.1 - 1.5e-12 47.7 0.0 1.9e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG15356.1 - 3.8e-09 36.6 0.0 6.8e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKG15356.1 - 1.4e-08 34.7 0.0 2.2e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG15356.1 - 1.5e-06 28.2 0.0 2.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG15356.1 - 5.1e-06 26.1 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKG15356.1 - 1.8e-05 24.9 0.0 2.4e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG15356.1 - 0.00095 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EKG15356.1 - 0.0042 16.9 0.0 0.05 13.4 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PQQ PF01011.16 EKG15356.1 - 0.07 12.6 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat MFS_1 PF07690.11 EKG15357.1 - 5.7e-24 84.4 18.3 1.1e-23 83.5 12.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.16 EKG15357.1 - 0.56 8.9 4.5 0.78 8.4 3.1 1.2 1 0 0 1 1 1 0 POT family NGP1NT PF08153.7 EKG15358.1 - 2.1e-48 163.5 0.2 3.4e-48 162.8 0.1 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EKG15358.1 - 7.2e-19 67.8 0.0 1.7e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKG15358.1 - 0.00025 20.8 0.1 0.53 10.0 0.0 3.6 2 1 1 3 3 3 1 Dynamin family FeoB_N PF02421.13 EKG15358.1 - 0.00028 20.1 0.0 0.0024 17.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EKG15358.1 - 0.00046 19.4 0.1 0.059 12.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG15358.1 - 0.0012 18.2 0.0 0.22 10.9 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EKG15358.1 - 0.0062 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Cwf_Cwc_15 PF04889.7 EKG15358.1 - 0.053 13.2 16.1 0.11 12.1 11.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein But2 PF09792.4 EKG15361.1 - 3.9e-33 114.2 0.2 8.2e-33 113.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Sod_Fe_N PF00081.17 EKG15363.1 - 1.1e-33 115.2 0.6 1.1e-33 115.2 0.4 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EKG15363.1 - 1.5e-31 108.3 0.1 2.5e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Hydantoinase_B PF02538.9 EKG15365.1 - 7.9e-203 674.4 0.5 7.8e-202 671.1 0.3 2.0 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EKG15365.1 - 3.5e-95 318.4 0.2 9.9e-95 316.9 0.2 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EKG15365.1 - 3.4e-59 199.2 2.7 3.8e-58 195.8 0.0 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region ATG22 PF11700.3 EKG15368.1 - 9e-81 271.7 9.2 1e-80 271.5 6.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EKG15368.1 - 6.1e-12 44.9 14.7 4.7e-08 32.1 2.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GntP_permease PF02447.11 EKG15368.1 - 0.073 11.5 2.1 0.12 10.8 1.5 1.2 1 0 0 1 1 1 0 GntP family permease Glyco_hydro_3 PF00933.16 EKG15369.1 - 4.1e-41 140.8 0.0 5.8e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EKG15369.1 - 1.8e-13 50.2 0.0 1.3e-06 28.3 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 EKG15369.1 - 3.1e-12 46.4 0.0 5.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.1 EKG15369.1 - 1.5e-10 41.0 0.0 9.2e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG15369.1 - 3.3e-09 36.8 0.0 3.3e-06 27.2 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG15369.1 - 5.7e-06 26.2 0.0 0.006 16.4 0.0 2.7 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG15369.1 - 0.02 14.6 0.0 1.9 8.3 0.0 2.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_CG PF14542.1 EKG15369.1 - 0.052 13.4 0.1 12 5.9 0.1 2.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EKG15369.1 - 0.11 12.2 0.0 0.39 10.4 0.0 1.9 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PAT1 PF09770.4 EKG15370.1 - 0.0023 16.2 4.0 0.0032 15.7 2.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EKG15370.1 - 0.016 14.6 18.5 0.021 14.2 12.8 1.2 1 0 0 1 1 1 0 Vta1 like Sporozoite_P67 PF05642.6 EKG15370.1 - 1.3 6.8 6.5 2.1 6.1 4.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC_membrane PF00664.18 EKG15371.1 - 5.1e-81 272.0 30.6 1.1e-40 139.7 8.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EKG15371.1 - 4.2e-66 221.4 0.0 1.2e-32 113.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKG15371.1 - 1.1e-11 44.3 0.0 2.7e-05 23.5 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG15371.1 - 3e-09 37.2 0.0 0.49 10.3 0.0 4.3 3 1 0 4 4 4 3 AAA domain ABC_ATPase PF09818.4 EKG15371.1 - 1.2e-08 34.0 1.9 0.00055 18.6 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EKG15371.1 - 4.6e-08 32.4 2.2 0.0006 19.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG15371.1 - 1.4e-07 31.6 2.4 0.00068 19.6 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EKG15371.1 - 3.7e-07 29.4 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG15371.1 - 1e-05 26.3 0.0 0.28 12.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EKG15371.1 - 1.6e-05 24.7 0.8 0.31 11.0 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EKG15371.1 - 6.3e-05 23.1 1.9 0.33 11.1 0.1 3.8 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKG15371.1 - 0.00039 19.8 3.7 0.46 9.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EKG15371.1 - 0.0022 17.9 0.5 1.1 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKG15371.1 - 0.0065 16.1 1.1 2.8 7.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EKG15371.1 - 0.0065 16.3 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG15371.1 - 0.012 15.8 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EKG15371.1 - 0.072 13.4 0.8 7.2 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EKG15371.1 - 0.097 12.4 1.9 0.6 9.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 G-alpha PF00503.15 EKG15371.1 - 0.1 11.2 0.0 2.6 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_10 PF12846.2 EKG15371.1 - 3.7 6.8 5.9 7.4 5.9 0.1 3.0 4 0 0 4 4 3 0 AAA-like domain KdpC PF02669.10 EKG15371.1 - 4.6 6.8 8.0 17 5.0 0.0 3.3 3 1 1 4 4 4 0 K+-transporting ATPase, c chain Fungal_trans PF04082.13 EKG15372.1 - 1.5e-20 73.1 0.2 2.4e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PC4 PF02229.11 EKG15373.1 - 6.4e-24 82.9 0.1 1.2e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) p450 PF00067.17 EKG15375.1 - 2.8e-66 223.9 0.0 4.1e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SIR2 PF02146.12 EKG15375.1 - 1.3e-54 184.5 0.0 2.1e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family MFS_1 PF07690.11 EKG15376.1 - 1.3e-25 89.8 44.6 1.8e-25 89.3 30.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15376.1 - 4.8e-07 28.7 9.5 4.8e-07 28.7 6.6 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter p450 PF00067.17 EKG15377.1 - 6e-61 206.3 0.0 7.7e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.9 EKG15378.1 - 1.5e-29 103.0 0.0 1.8e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ERG4_ERG24 PF01222.12 EKG15379.1 - 4.7e-132 440.5 18.4 5.6e-132 440.3 12.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_23 PF13489.1 EKG15380.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15380.1 - 0.0023 18.4 0.5 0.023 15.2 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG15380.1 - 0.0069 15.7 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EKG15380.1 - 0.0076 15.8 0.0 0.27 10.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EKG15380.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sugar_tr PF00083.19 EKG15381.1 - 1.8e-116 389.4 18.7 2e-116 389.2 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15381.1 - 1e-23 83.6 26.5 1e-23 83.6 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_23 PF13489.1 EKG15382.1 - 1.2e-25 90.1 0.0 1.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15382.1 - 2.7e-10 40.8 0.1 6.3e-09 36.4 0.1 2.6 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG15382.1 - 7.9e-10 39.1 0.0 7.2e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15382.1 - 9.3e-10 38.2 0.0 1.7e-08 34.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15382.1 - 2e-08 34.6 0.0 5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG15382.1 - 2.2e-05 23.8 0.0 8.5e-05 21.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EKG15382.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EKG15382.1 - 0.0013 19.0 0.0 0.0041 17.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG15382.1 - 0.0015 18.5 0.0 0.0092 16.0 0.0 2.3 3 1 0 3 3 3 1 Methyltransferase domain PrmA PF06325.8 EKG15382.1 - 0.004 16.3 0.0 0.0065 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EKG15382.1 - 0.0041 16.2 0.0 0.28 10.2 0.0 3.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Exc PF07825.6 EKG15382.1 - 0.079 12.7 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Excisionase-like protein CheR PF01739.13 EKG15382.1 - 0.11 11.8 0.0 0.36 10.0 0.0 1.8 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain 2OG-FeII_Oxy PF03171.15 EKG15383.1 - 5.7e-13 49.0 0.0 9.2e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhzC-PhzF PF02567.11 EKG15383.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein DIOX_N PF14226.1 EKG15383.1 - 0.04 14.4 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal HMGL-like PF00682.14 EKG15384.1 - 8.1e-56 189.3 0.0 1.1e-55 188.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like DIOX_N PF14226.1 EKG15385.1 - 3e-14 53.5 0.0 4.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG15385.1 - 1.1e-08 35.2 0.0 2.6e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EKG15386.1 - 1.6e-21 76.3 0.0 1.8e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.15 EKG15387.1 - 3.5e-19 68.9 0.0 5.6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EKG15387.1 - 5.4e-19 68.8 0.1 1.6e-18 67.3 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal TetR_C_6 PF13977.1 EKG15387.1 - 0.021 14.8 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional repressor DIOX_N PF14226.1 EKG15388.1 - 1.8e-20 73.5 0.1 3.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG15388.1 - 4.9e-16 58.8 0.0 1.8e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EKG15389.1 - 4.8e-05 23.7 0.0 0.00012 22.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 EKG15389.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase AMP-binding PF00501.23 EKG15390.1 - 0 1074.0 0.8 1.5e-85 287.1 0.0 4.4 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EKG15390.1 - 4.5e-151 501.8 0.0 1.2e-40 139.2 0.0 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EKG15390.1 - 9.9e-47 157.0 0.5 4.9e-11 42.7 0.0 5.3 5 0 0 5 5 5 4 Phosphopantetheine attachment site GH3 PF03321.8 EKG15390.1 - 0.0011 17.6 0.2 5.9 5.2 0.0 5.1 7 0 0 7 7 7 1 GH3 auxin-responsive promoter GXGXG PF01493.14 EKG15390.1 - 0.83 8.6 1.9 17 4.3 0.0 3.0 3 0 0 3 3 3 0 GXGXG motif Fiji_64_capsid PF05880.6 EKG15390.1 - 2.6 6.2 0.0 4 5.6 0.0 1.1 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein MS_channel PF00924.13 EKG15390.1 - 9.1 5.5 0.2 32 3.7 0.0 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel ABC_tran PF00005.22 EKG15392.1 - 6.1e-47 159.3 0.0 2.4e-29 102.3 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKG15392.1 - 8.9e-22 77.7 3.0 1.3e-21 77.2 2.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EKG15392.1 - 1.8e-10 40.4 0.3 0.0027 16.9 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKG15392.1 - 1.1e-06 27.9 0.2 0.0034 16.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG15392.1 - 2e-06 27.9 7.5 0.00098 19.1 2.6 3.2 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EKG15392.1 - 5.9e-05 23.2 0.4 0.73 9.9 0.0 3.3 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EKG15392.1 - 0.00019 21.3 0.1 0.28 11.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EKG15392.1 - 0.00022 21.3 0.0 3.9 7.3 0.0 4.0 3 1 0 4 4 4 1 AAA domain DUF87 PF01935.12 EKG15392.1 - 0.00027 20.8 0.9 0.028 14.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EKG15392.1 - 0.00034 21.0 0.1 1.4 9.4 0.1 2.5 2 0 0 2 2 2 2 Miro-like protein NB-ARC PF00931.17 EKG15392.1 - 0.00041 19.3 0.2 1.9 7.2 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_23 PF13476.1 EKG15392.1 - 0.00059 20.2 0.0 0.58 10.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EKG15392.1 - 0.00075 18.4 0.0 0.51 9.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EKG15392.1 - 0.00093 18.7 0.0 0.07 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 EKG15392.1 - 0.0013 17.8 0.2 1.4 7.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin DUF258 PF03193.11 EKG15392.1 - 0.0017 17.5 0.4 0.18 10.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EKG15392.1 - 0.0043 16.5 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF2075 PF09848.4 EKG15392.1 - 0.0051 15.8 0.4 0.42 9.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EKG15392.1 - 0.0078 15.8 2.2 0.79 9.3 0.1 2.8 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EKG15392.1 - 0.014 16.2 0.0 0.88 10.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EKG15392.1 - 0.023 14.0 7.3 0.27 10.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EKG15392.1 - 0.028 14.2 0.0 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EKG15392.1 - 0.051 13.5 4.4 3.3 7.6 0.0 4.5 4 1 1 5 5 4 0 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EKG15392.1 - 0.052 13.2 0.7 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EKG15392.1 - 0.061 13.5 0.1 17 5.5 0.0 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EKG15392.1 - 0.096 12.5 1.9 6 6.6 0.2 2.3 2 0 0 2 2 2 0 Dynamin family Viral_helicase1 PF01443.13 EKG15392.1 - 0.1 12.0 0.2 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EKG15392.1 - 0.2 11.9 0.2 6.2 7.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain Adeno_IVa2 PF02456.10 EKG15392.1 - 0.21 10.2 0.1 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein RNA_helicase PF00910.17 EKG15392.1 - 0.24 11.5 0.0 32 4.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 EKG15392.1 - 0.28 10.7 2.9 9.5 5.7 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EKG15392.1 - 0.28 10.9 1.6 11 5.8 0.0 3.5 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) DUF1593 PF07632.6 EKG15393.1 - 1.5e-80 270.2 0.0 1.9e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EKG15393.1 - 0.0086 14.4 0.0 0.013 13.8 0.0 1.1 1 0 0 1 1 1 1 REJ domain MFS_1 PF07690.11 EKG15394.1 - 2.5e-32 111.9 42.7 1.7e-24 86.2 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15394.1 - 0.00065 18.3 8.5 0.00065 18.3 5.9 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter AMP-binding PF00501.23 EKG15398.1 - 7.5e-161 535.1 0.0 8.9e-82 274.6 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EKG15398.1 - 5.2e-68 229.1 0.0 1.1e-40 139.4 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EKG15398.1 - 3e-22 78.6 0.1 4.1e-06 26.9 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG15398.1 - 2.9e-09 37.7 0.0 3.7e-06 27.7 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain NO_synthase PF02898.10 EKG15398.1 - 0.044 12.4 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain Methyltransf_2 PF00891.13 EKG15399.1 - 3.6e-36 124.5 0.1 5.9e-36 123.8 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EKG15399.1 - 2e-09 38.0 1.3 3.6e-08 33.9 0.3 3.0 3 2 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG15399.1 - 0.00014 21.8 0.3 0.00062 19.7 0.2 2.1 1 0 0 1 1 1 1 Methyltransferase domain TetR_C PF02909.12 EKG15399.1 - 0.0046 16.6 0.9 0.038 13.6 0.2 2.3 2 0 0 2 2 2 1 Tetracyclin repressor, C-terminal all-alpha domain KGG PF10685.4 EKG15399.1 - 0.017 15.0 0.3 0.058 13.3 0.2 1.9 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif Methyltransf_12 PF08242.7 EKG15399.1 - 0.045 14.2 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ank_2 PF12796.2 EKG15400.1 - 3.7e-51 171.3 0.0 1.5e-12 47.6 0.0 3.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EKG15400.1 - 2e-26 90.4 1.5 3.9e-06 26.3 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EKG15400.1 - 3.6e-20 71.5 1.9 1.6e-06 28.1 0.1 6.6 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG15400.1 - 1e-19 70.5 0.0 9.7e-06 25.9 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG15400.1 - 3.1e-18 64.0 0.0 0.014 15.5 0.0 6.9 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.7 EKG15400.1 - 4.4e-06 26.4 0.4 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.1 EKG15400.1 - 0.0067 16.0 0.0 0.034 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKG15400.1 - 0.044 12.6 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 EKG15400.1 - 0.055 13.6 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EKG15400.1 - 0.18 10.7 0.0 0.88 8.4 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain Yip1 PF04893.12 EKG15401.1 - 0.13 11.7 4.0 0.22 10.9 2.8 1.2 1 0 0 1 1 1 0 Yip1 domain Fig1 PF12351.3 EKG15402.1 - 6.3e-05 22.9 0.3 7.8e-05 22.6 0.2 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 LIME1 PF15332.1 EKG15403.1 - 0.23 10.6 1.7 0.39 9.9 1.2 1.3 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 MIP-T3 PF10243.4 EKG15404.1 - 0.77 8.1 59.3 0.93 7.8 41.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Patatin PF01734.17 EKG15405.1 - 1.7e-25 90.1 1.0 5.8e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 Patatin-like phospholipase DUF3336 PF11815.3 EKG15405.1 - 5.8e-15 55.0 0.0 9e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) tRNA-synt_2 PF00152.15 EKG15407.1 - 5.3e-108 360.7 0.0 6.8e-108 360.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EKG15407.1 - 1.5e-05 24.6 0.0 0.00023 20.7 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 EKG15407.1 - 0.00054 19.2 0.1 0.0015 17.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) CS PF04969.11 EKG15408.1 - 1.9e-18 66.7 1.9 3.7e-18 65.8 0.1 2.2 2 1 0 2 2 2 1 CS domain Bactofilin PF04519.8 EKG15408.1 - 0.068 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Polymer-forming cytoskeletal ANTH PF07651.11 EKG15409.1 - 5e-48 163.2 0.8 5e-48 163.2 0.6 2.0 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 EKG15409.1 - 0.0046 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 ENTH domain Polysacc_synt_4 PF04669.8 EKG15410.1 - 1.5e-25 89.6 1.4 8.1e-25 87.2 1.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis ABC_membrane PF00664.18 EKG15411.1 - 9.7e-70 235.1 27.9 1.3e-35 123.1 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EKG15411.1 - 2.6e-43 147.6 0.0 2.2e-28 99.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKG15411.1 - 1.5e-09 37.4 0.4 1.3e-07 31.1 0.1 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EKG15411.1 - 9e-09 36.1 0.0 0.0015 19.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKG15411.1 - 2.7e-08 33.1 1.7 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EKG15411.1 - 4.7e-06 26.5 0.0 0.01 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EKG15411.1 - 4.8e-06 26.8 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKG15411.1 - 4.9e-06 26.6 0.1 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EKG15411.1 - 3.3e-05 24.0 1.5 0.062 13.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EKG15411.1 - 0.00015 21.4 0.1 0.49 10.0 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_21 PF13304.1 EKG15411.1 - 0.00017 21.6 0.1 0.053 13.4 0.1 3.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKG15411.1 - 0.00038 19.6 0.0 0.89 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EKG15411.1 - 0.00043 19.7 0.1 0.76 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EKG15411.1 - 0.0019 17.7 0.0 1.9 7.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_5 PF07728.9 EKG15411.1 - 0.0021 17.7 0.0 3.3 7.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EKG15411.1 - 0.011 15.6 0.0 1.4 8.9 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EKG15411.1 - 0.012 15.0 8.2 0.37 10.1 0.2 3.1 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 EKG15411.1 - 0.012 15.2 2.4 0.3 10.7 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EKG15411.1 - 0.015 14.2 0.3 0.3 9.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EKG15411.1 - 0.028 13.5 0.1 0.61 9.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EKG15411.1 - 0.039 13.8 0.0 5.6 6.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.12 EKG15411.1 - 0.065 13.0 7.7 0.45 10.2 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 Mg_chelatase PF01078.16 EKG15411.1 - 0.15 11.1 0.0 9.9 5.2 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EKG15411.1 - 0.15 11.6 1.5 7 6.2 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EKG15411.1 - 0.17 12.1 0.0 18 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EKG15411.1 - 0.18 11.3 0.1 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EKG15411.1 - 0.19 12.2 0.0 32 5.0 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 EKG15411.1 - 0.21 11.7 0.2 33 4.7 0.0 3.1 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.1 EKG15411.1 - 0.52 9.8 2.7 9.3 5.7 0.1 2.9 3 0 0 3 3 3 0 AAA domain Ribophorin_II PF05817.9 EKG15412.1 - 1.5e-26 92.8 0.0 1.8e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II MscS_TM PF12794.2 EKG15412.1 - 0.11 11.0 1.8 1.1 7.8 0.1 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DIOX_N PF14226.1 EKG15413.1 - 1.1e-20 74.2 0.1 2.5e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG15413.1 - 1.9e-11 44.1 0.0 3.7e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EKG15414.1 - 1.2e-18 67.0 2.5 1.5e-18 66.6 1.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RNase_H PF00075.19 EKG15415.1 - 1.1e-10 41.9 0.0 2.4e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 RNase H MARVEL PF01284.18 EKG15416.1 - 0.0024 17.7 20.1 0.0031 17.3 13.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain ERG4_ERG24 PF01222.12 EKG15416.1 - 0.089 11.3 3.4 0.048 12.2 0.9 1.5 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family RseC_MucC PF04246.7 EKG15416.1 - 1.2 8.6 7.0 1.4 8.5 2.6 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF4018 PF13210.1 EKG15416.1 - 4.1 6.7 11.2 0.7 9.2 4.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) DUF4231 PF14015.1 EKG15416.1 - 8.5 6.4 6.4 14 5.7 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Caleosin PF05042.8 EKG15417.1 - 1.2e-54 184.5 0.0 1.5e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_7 PF13499.1 EKG15417.1 - 0.00082 19.4 0.4 0.36 10.9 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EKG15417.1 - 0.042 13.1 1.9 0.75 9.2 0.1 2.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EKG15417.1 - 0.1 12.5 6.6 0.082 12.8 0.6 2.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 EKG15417.1 - 0.11 12.1 0.4 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair Fe-ADH PF00465.14 EKG15419.1 - 5.9e-68 229.1 2.4 8.9e-68 228.5 1.6 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EKG15419.1 - 7e-12 45.1 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1967 PF09269.6 EKG15419.1 - 0.028 14.0 0.1 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Zip PF02535.17 EKG15420.1 - 2.9e-54 184.2 8.1 3.3e-54 184.0 5.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Bac_rhodopsin PF01036.13 EKG15421.1 - 7e-50 169.3 16.1 8.7e-50 169.0 11.1 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Wzy_C PF04932.10 EKG15421.1 - 0.0084 15.9 0.6 0.0084 15.9 0.4 2.1 1 1 0 2 2 2 1 O-Antigen ligase DUF3278 PF11683.3 EKG15421.1 - 0.59 10.1 2.2 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) VIT1 PF01988.14 EKG15421.1 - 8.9 5.7 8.5 0.7 9.3 0.4 2.3 2 0 0 2 2 2 0 VIT family NmrA PF05368.8 EKG15422.1 - 2.1e-42 144.9 0.0 3e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG15422.1 - 1.1e-10 41.8 0.2 1.8e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG15422.1 - 2.1e-05 23.4 0.1 3.1e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EKG15422.1 - 0.00015 20.8 0.1 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EKG15422.1 - 0.00032 20.6 0.1 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EKG15422.1 - 0.00052 19.5 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EKG15422.1 - 0.001 18.9 0.5 0.0018 18.2 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15422.1 - 0.0029 17.3 0.2 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EKG15422.1 - 0.025 14.8 0.1 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4532 PF15046.1 EKG15422.1 - 0.16 10.9 0.4 13 4.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4532) RPEL PF02755.10 EKG15423.1 - 2.2e-31 106.2 15.3 5.3e-11 41.4 0.2 3.8 4 0 0 4 4 4 3 RPEL repeat Rotamase_3 PF13616.1 EKG15423.1 - 0.016 15.4 0.4 0.81 9.9 0.1 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain NADH_u_ox_C PF12853.2 EKG15423.1 - 0.093 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF1992 PF09350.5 EKG15423.1 - 0.43 10.4 4.7 3.5 7.5 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1992) adh_short PF00106.20 EKG15424.1 - 1.2e-17 64.3 1.0 4.3e-17 62.5 0.8 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG15424.1 - 4.3e-10 39.5 0.2 9.6e-10 38.4 0.1 1.5 2 0 0 2 2 2 1 KR domain ABC2_membrane PF01061.19 EKG15426.1 - 5.4e-36 123.7 20.3 5.4e-36 123.7 14.0 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EKG15426.1 - 5.4e-27 94.7 0.0 9.9e-27 93.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKG15426.1 - 8.3e-09 35.8 0.0 5.3e-08 33.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EKG15426.1 - 2.4e-07 30.0 29.7 1.3e-06 27.7 20.6 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 EKG15426.1 - 0.00072 19.0 0.1 0.042 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKG15426.1 - 0.0038 16.4 0.0 0.0096 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 EKG15426.1 - 0.0046 15.8 21.0 0.011 14.6 7.5 3.1 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_17 PF13207.1 EKG15426.1 - 0.016 16.0 0.0 0.041 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EKG15426.1 - 0.02 14.4 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG15426.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EKG15426.1 - 0.057 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKG15426.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EKG15426.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EKG15426.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EKG15426.1 - 0.16 10.9 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EKG15426.1 - 0.27 10.0 0.0 0.47 9.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein hEGF PF12661.2 EKG15426.1 - 1.6 8.9 29.7 0.089 12.9 1.1 4.3 4 0 0 4 4 3 0 Human growth factor-like EGF Aminotran_1_2 PF00155.16 EKG15427.1 - 3.7e-44 151.1 0.0 4.6e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EKG15427.1 - 1.1e-08 34.2 0.0 1.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EKG15427.1 - 1.4e-06 27.6 0.0 2.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EKG15427.1 - 2.2e-05 22.9 0.0 3.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EKG15427.1 - 0.00026 20.1 0.0 0.00061 18.9 0.0 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EKG15427.1 - 0.0034 16.0 0.1 0.0073 14.9 0.1 1.4 1 1 0 1 1 1 1 Allinase EnY2 PF10163.4 EKG15427.1 - 0.058 13.3 0.3 43 4.1 0.0 3.5 4 0 0 4 4 4 0 Transcription factor e(y)2 LigD_N PF13298.1 EKG15428.1 - 1.1e-11 44.7 0.0 3.9e-11 42.9 0.0 1.8 1 1 1 2 2 2 1 DNA polymerase Ligase (LigD) EF-hand_7 PF13499.1 EKG15429.1 - 1.5e-12 47.4 0.6 1e-09 38.3 0.1 3.3 2 0 0 2 2 2 2 EF-hand domain pair ZZ PF00569.12 EKG15429.1 - 1.7e-12 46.6 4.5 3e-12 45.8 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 EKG15429.1 - 3.2e-12 44.8 12.2 9.2e-05 21.4 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EKG15429.1 - 5.6e-10 38.2 5.5 0.00075 19.1 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EKG15429.1 - 1.2e-08 34.3 2.6 0.018 14.6 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EKG15429.1 - 4.2e-05 22.6 11.0 0.07 12.5 0.2 4.3 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EKG15429.1 - 0.028 14.1 0.4 3.3 7.5 0.0 3.0 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand IL32 PF15225.1 EKG15429.1 - 0.78 9.7 2.6 29 4.6 0.1 2.9 2 0 0 2 2 2 0 Interleukin 32 PRANC PF09372.5 EKG15430.1 - 0.014 15.3 0.1 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 PRANC domain WD40 PF00400.27 EKG15431.1 - 7.4e-40 133.4 9.9 2.2e-12 46.3 0.2 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EKG15431.1 - 0.0017 16.5 0.1 0.14 10.2 0.0 2.5 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Cornichon PF03311.9 EKG15432.1 - 6.9e-55 184.6 11.9 7.8e-55 184.4 8.3 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M24 PF00557.19 EKG15433.1 - 2.8e-44 151.1 0.0 3.6e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EKG15433.1 - 0.00023 20.9 7.2 0.00023 20.9 5.0 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EKG15433.1 - 0.46 10.1 4.9 1.4 8.6 3.4 1.9 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 EKG15434.1 - 4.5e-19 68.7 0.0 1.8e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EKG15434.1 - 9.1e-06 26.0 0.0 0.00044 20.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG15434.1 - 0.00031 20.7 0.2 0.00085 19.3 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG15434.1 - 0.001 18.0 0.0 0.0024 16.8 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG15434.1 - 0.0013 17.2 0.1 0.0019 16.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EKG15434.1 - 0.004 17.0 0.1 0.0069 16.2 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG15434.1 - 0.005 15.9 0.5 0.22 10.5 0.4 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG15434.1 - 0.0077 15.1 0.2 0.44 9.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EKG15434.1 - 0.012 14.5 0.1 0.033 13.0 0.1 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A GABP-alpha PF11620.3 EKG15434.1 - 0.031 14.2 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 GA-binding protein alpha chain SE PF08491.5 EKG15434.1 - 0.075 11.8 0.0 0.2 10.4 0.0 1.7 1 0 0 1 1 1 0 Squalene epoxidase CytochromB561_N PF09786.4 EKG15435.1 - 1.1 7.6 7.7 1.2 7.4 5.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Memo PF01875.12 EKG15436.1 - 9.3e-79 264.1 0.0 1.1e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Glyco_hydro_3 PF00933.16 EKG15437.1 - 4.1e-86 288.6 0.0 7e-86 287.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG15437.1 - 3e-47 161.0 0.2 2.3e-46 158.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG15437.1 - 4.2e-21 74.6 0.1 8.7e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1769 PF08588.5 EKG15438.1 - 9.7e-25 86.2 0.4 1.7e-24 85.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) BRCT PF00533.21 EKG15440.1 - 0.042 13.9 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Cupin_2 PF07883.6 EKG15441.1 - 5.6e-06 25.7 0.2 9.5e-06 25.0 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EKG15441.1 - 6.5e-06 25.6 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EKG15441.1 - 0.0013 18.3 0.1 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EKG15441.1 - 0.006 16.5 0.0 0.0067 16.3 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_3 PF05899.7 EKG15441.1 - 0.017 14.4 0.1 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) AraC_binding PF02311.14 EKG15441.1 - 0.024 14.3 0.1 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Peptidase_S10 PF00450.17 EKG15442.1 - 1.7e-13 50.5 0.0 1.3e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EKG15442.1 - 0.051 13.4 0.0 0.23 11.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Acyl-CoA_dh_1 PF00441.19 EKG15443.1 - 2e-40 138.3 0.6 3.1e-40 137.7 0.2 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EKG15443.1 - 7.2e-21 73.4 0.2 1.4e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EKG15443.1 - 3.5e-18 65.1 0.2 6.4e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EKG15443.1 - 3.8e-16 59.6 0.1 1.7e-15 57.5 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EKG15443.1 - 2.7e-07 30.9 0.0 4.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cys_rich_VLP PF14194.1 EKG15443.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP ADH_N PF08240.7 EKG15444.1 - 2.3e-23 82.0 0.7 3.7e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG15444.1 - 0.019 14.4 0.0 0.053 13.0 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Cupin_2 PF07883.6 EKG15445.1 - 6.3e-12 44.8 0.1 9.9e-12 44.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EKG15445.1 - 9.5e-07 28.3 0.1 1.3e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EKG15445.1 - 0.0013 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EKG15445.1 - 0.0013 18.0 0.0 0.0039 16.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EKG15445.1 - 0.056 13.0 0.1 0.074 12.6 0.1 1.3 1 1 0 1 1 1 0 Cupin DUF4437 PF14499.1 EKG15445.1 - 0.12 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Glyco_hydro_92 PF07971.7 EKG15446.1 - 2.6e-151 504.7 0.6 3e-151 504.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Na_H_Exchanger PF00999.16 EKG15447.1 - 4.3e-69 232.8 46.7 5.6e-69 232.4 32.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RNase_H PF00075.19 EKG15449.1 - 0.0052 17.1 0.0 0.0069 16.7 0.0 1.2 1 0 0 1 1 1 1 RNase H 3Beta_HSD PF01073.14 EKG15450.1 - 1.5e-21 76.3 0.0 6.7e-21 74.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG15450.1 - 7.9e-11 41.3 0.0 1.8e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EKG15450.1 - 2.4e-10 40.2 0.0 4.9e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG15450.1 - 0.001 18.0 0.0 0.021 13.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EKG15450.1 - 0.013 14.4 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EKG15450.1 - 0.06 13.3 0.7 0.58 10.1 0.5 2.6 1 1 0 1 1 1 0 NADH(P)-binding DUF4129 PF13559.1 EKG15450.1 - 0.47 10.4 3.5 4.2 7.4 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4129) DUF4603 PF15376.1 EKG15451.1 - 0.87 6.6 8.2 1.1 6.3 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MFS_1 PF07690.11 EKG15453.1 - 1.6e-32 112.6 23.2 2.4e-32 112.0 16.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG15453.1 - 5e-10 38.2 6.3 6e-10 37.9 4.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EKG15454.1 - 4.7e-59 200.1 0.0 8.3e-39 133.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 tRNA-synt_1 PF00133.17 EKG15457.1 - 1.1e-117 393.6 0.0 1.4e-117 393.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EKG15457.1 - 3.4e-19 69.1 0.0 5.7e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EKG15457.1 - 6.9e-07 28.2 0.0 0.058 12.0 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EKG15457.1 - 0.00017 21.1 5.3 0.00031 20.2 3.7 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EKG15457.1 - 0.045 13.0 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 DUF221 PF02714.10 EKG15458.1 - 2.8e-95 318.9 12.9 2.8e-95 318.9 8.9 2.8 3 1 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EKG15458.1 - 6.8e-40 136.1 4.7 6.8e-40 136.1 3.2 2.6 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EKG15458.1 - 3.2e-21 75.0 0.2 7.7e-21 73.7 0.1 1.8 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EKG15458.1 - 1.4e-13 51.1 0.4 3e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RhgB_N PF09284.5 EKG15459.1 - 1e-103 346.0 6.9 1.7e-103 345.3 4.8 1.4 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EKG15459.1 - 2.3e-56 189.9 0.0 1.1e-55 187.8 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EKG15459.1 - 7.7e-17 61.2 3.1 1.7e-16 60.0 2.2 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EKG15459.1 - 0.0079 16.2 1.3 0.034 14.2 0.8 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Endonuc-MspI PF09208.5 EKG15460.1 - 0.021 13.9 0.1 0.025 13.6 0.1 1.0 1 0 0 1 1 1 0 Restriction endonuclease MspI DAHP_synth_2 PF01474.11 EKG15461.1 - 2e-195 649.2 0.0 2.3e-195 649.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Amidase PF01425.16 EKG15462.1 - 3.2e-78 263.5 0.0 3.6e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.1 EKG15463.1 - 7.6e-23 81.5 0.0 8.6e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG15463.1 - 5.3e-22 78.5 0.4 6.6e-22 78.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15463.1 - 3.1e-11 43.2 0.1 4.1e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Kinesin PF00225.18 EKG15465.1 - 2.3e-112 375.0 0.3 6.8e-112 373.4 0.2 1.9 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EKG15465.1 - 2.6e-08 34.1 1.6 2.6e-08 34.1 1.1 5.2 4 1 1 6 6 6 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.7 EKG15465.1 - 0.022 14.5 0.2 0.022 14.5 0.1 6.7 2 1 5 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_C41 PF05417.6 EKG15465.1 - 0.038 13.5 0.0 0.14 11.6 0.0 2.0 1 0 0 1 1 1 0 Hepatitis E cysteine protease UPF0183 PF03676.9 EKG15466.1 - 1.1e-16 60.4 0.0 3.1e-06 26.0 0.0 4.5 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) CorA PF01544.13 EKG15467.1 - 7.4e-15 54.7 4.4 7.1e-14 51.5 2.9 2.5 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Bacillus_HBL PF05791.6 EKG15467.1 - 0.018 14.3 0.5 0.042 13.2 0.4 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) NmrA PF05368.8 EKG15468.1 - 1.1e-25 90.2 0.0 1.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG15468.1 - 1.9e-05 24.7 0.1 5.2e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG15468.1 - 0.0042 15.8 0.0 0.0061 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKG15468.1 - 0.02 14.2 0.1 0.045 13.1 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EKG15468.1 - 0.023 14.3 0.1 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EKG15468.1 - 0.083 12.7 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase zf-CW PF07496.10 EKG15469.1 - 0.062 13.0 0.6 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger hSH3 PF14603.1 EKG15469.1 - 0.1 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain SEC-C PF02810.10 EKG15470.1 - 0.48 10.0 8.6 1.3 8.6 0.6 3.2 3 0 0 3 3 3 0 SEC-C motif TLD PF07534.11 EKG15472.1 - 6.4e-23 81.2 0.0 1.8e-22 79.8 0.0 1.8 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 EKG15472.1 - 3.3e-05 24.0 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal PET PF06297.9 EKG15472.1 - 0.17 11.5 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 PET Domain PIH1 PF08190.7 EKG15474.1 - 0.028 13.8 2.7 0.035 13.5 1.9 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Peptidase_C9 PF01707.11 EKG15474.1 - 0.11 12.1 0.1 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C9 ATC_hydrolase PF14196.1 EKG15474.1 - 0.24 11.8 1.0 0.34 11.2 0.7 1.2 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase PIH1 PF08190.7 EKG15475.1 - 0.084 12.3 0.1 0.1 12.0 0.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 VirionAssem_T7 PF11653.3 EKG15475.1 - 1.2 9.9 6.4 1.7 9.4 4.4 1.2 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Myb_DNA-binding PF00249.26 EKG15476.1 - 0.038 14.0 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain HTH_WhiA PF02650.9 EKG15476.1 - 0.053 13.9 0.1 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Myb_DNA-bind_6 PF13921.1 EKG15476.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain YbaB_DNA_bd PF02575.11 EKG15481.1 - 0.038 13.8 0.3 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family vWA-TerF-like PF10138.4 EKG15483.1 - 4.2e-06 26.7 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EKG15483.1 - 9.7e-06 25.7 0.1 4e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKG15483.1 - 0.0042 16.8 0.9 0.11 12.1 0.1 3.0 2 1 0 3 3 3 1 von Willebrand factor type A domain SPO22 PF08631.5 EKG15483.1 - 0.027 13.5 0.0 0.35 9.9 0.0 2.1 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF3067 PF11267.3 EKG15483.1 - 0.053 13.6 0.1 0.25 11.4 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3067) FAD_binding_3 PF01494.14 EKG15484.1 - 1.1e-30 106.9 0.1 5.4e-30 104.6 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG15484.1 - 8.2e-07 28.2 0.1 0.0012 17.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG15484.1 - 0.00013 20.9 0.3 0.0084 14.9 0.0 2.1 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG15484.1 - 0.0003 20.7 0.0 0.00073 19.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG15484.1 - 0.002 17.1 0.0 0.03 13.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EKG15484.1 - 0.0033 17.7 0.0 0.079 13.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG15484.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EKG15484.1 - 0.084 11.6 0.0 3.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_10 PF13460.1 EKG15485.1 - 4.7e-25 88.6 0.0 5.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG15485.1 - 1.1e-05 24.7 0.3 2.1e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EKG15485.1 - 2.8e-05 23.6 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EKG15485.1 - 0.044 13.7 0.0 0.065 13.2 0.0 1.4 1 1 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EKG15485.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.13 EKG15486.1 - 3.9e-15 55.4 2.3 6.5e-15 54.7 0.8 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG15486.1 - 6.9e-06 25.8 10.8 1.4e-05 24.9 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EKG15487.1 - 2.2e-07 29.8 3.1 2.6e-07 29.5 2.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Aminoglyc_resit PF10706.4 EKG15487.1 - 0.042 13.4 0.4 0.074 12.6 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside-2''-adenylyltransferase HET PF06985.6 EKG15489.1 - 0.02 15.0 0.1 0.037 14.1 0.1 1.4 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Curlin_rpt PF07012.7 EKG15490.1 - 0.021 14.5 0.2 0.056 13.1 0.0 1.7 2 0 0 2 2 2 0 Curlin associated repeat DUF2852 PF11014.3 EKG15490.1 - 0.097 12.6 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) PilO PF04350.8 EKG15490.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Pilus assembly protein, PilO Zn_clus PF00172.13 EKG15491.1 - 0.00019 21.2 1.1 0.00019 21.2 0.8 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.19 EKG15492.1 - 1.1e-46 159.8 0.5 3.2e-46 158.3 0.3 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKG15492.1 - 1.5e-12 47.3 0.1 3.9e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG15492.1 - 2.4e-09 36.5 1.6 2.2e-07 30.0 0.3 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG15492.1 - 2.3e-07 30.0 0.2 5.3e-07 28.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EKG15492.1 - 3e-07 29.7 0.0 4.7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EKG15492.1 - 4.6e-06 25.3 0.1 8.8e-06 24.4 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EKG15492.1 - 5.1e-06 25.8 0.7 1.9e-05 23.9 0.3 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG15492.1 - 5.7e-06 25.4 0.0 3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EKG15492.1 - 9.3e-06 25.6 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG15492.1 - 6.2e-05 23.3 0.4 0.00019 21.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG15492.1 - 9.5e-05 21.4 0.1 0.00021 20.2 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EKG15492.1 - 0.00076 19.5 1.0 0.0037 17.3 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG15492.1 - 0.00096 18.3 0.1 0.008 15.2 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 EKG15492.1 - 0.003 17.3 0.5 0.07 12.8 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding GDI PF00996.13 EKG15492.1 - 0.018 13.4 0.0 0.026 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor OPT PF03169.10 EKG15493.1 - 2.9e-183 610.7 49.8 3.3e-183 610.5 34.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 EKG15493.1 - 0.32 9.9 2.2 0.27 10.2 0.3 1.8 2 0 0 2 2 2 0 E1-E2 ATPase p450 PF00067.17 EKG15494.1 - 1.7e-15 56.5 0.0 1.7e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 STAS_2 PF13466.1 EKG15494.1 - 0.099 12.6 0.4 0.76 9.8 0.1 2.3 2 0 0 2 2 2 0 STAS domain Bac_luciferase PF00296.15 EKG15495.1 - 1.6e-65 221.2 1.0 2.1e-65 220.8 0.7 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_N PF08240.7 EKG15496.1 - 4.7e-20 71.3 0.8 9.6e-20 70.3 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG15496.1 - 1.3e-09 37.6 0.1 4.3e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG15496.1 - 0.00023 20.3 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG15496.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_18 PF12847.2 EKG15496.1 - 0.011 16.2 0.0 0.034 14.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DAO PF01266.19 EKG15496.1 - 0.013 14.4 0.3 0.02 13.8 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EKG15496.1 - 0.026 14.1 0.1 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG15496.1 - 0.047 14.1 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EKG15496.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_60s PF00428.14 EKG15497.1 - 0.0027 18.0 2.2 0.008 16.5 1.5 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein Abhydrolase_6 PF12697.2 EKG15498.1 - 7.5e-13 48.8 0.2 9.8e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family EHN PF06441.7 EKG15498.1 - 4.4e-10 39.4 1.1 5.7e-10 39.1 0.1 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_5 PF12695.2 EKG15498.1 - 0.00018 21.3 0.2 0.00034 20.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG15498.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Tom37_C PF11801.3 EKG15501.1 - 1.6e-27 96.4 0.0 2.4e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EKG15501.1 - 3.2e-21 75.3 0.0 9.5e-21 73.8 0.0 1.9 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EKG15501.1 - 0.0074 16.1 0.3 0.043 13.7 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG15501.1 - 0.02 15.3 0.2 0.77 10.2 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TPP1 PF10341.4 EKG15502.1 - 3.2e-12 46.3 0.0 6.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD PIP5K PF01504.13 EKG15503.1 - 1.3e-59 201.3 2.5 2.5e-59 200.4 1.7 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EKG15503.1 - 1e-26 93.6 0.0 1.8e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EKG15503.1 - 3e-14 52.6 6.5 3e-14 52.6 4.5 2.2 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.17 EKG15503.1 - 0.01 15.5 3.5 0.031 14.0 2.5 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_binding_10 PF13460.1 EKG15505.1 - 6e-05 23.1 0.0 7.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding polyprenyl_synt PF00348.12 EKG15506.1 - 6.6e-56 189.0 0.0 8.6e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 EKG15507.1 - 2.6e-42 144.9 0.0 2.9e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 EKG15508.1 - 1.5e-05 24.3 0.3 3.3e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain ATC_hydrolase PF14196.1 EKG15508.1 - 0.00096 19.5 0.7 0.94 9.8 0.2 2.4 2 1 0 2 2 2 2 L-2-amino-thiazoline-4-carboxylic acid hydrolase HMG_CoA_synt_C PF08540.5 EKG15509.1 - 8.7e-100 333.8 0.1 1.3e-72 244.6 0.0 2.1 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EKG15509.1 - 4.1e-92 306.4 0.3 7.4e-92 305.6 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Collagen PF01391.13 EKG15509.1 - 7.2e-08 31.8 16.3 1.9e-07 30.5 11.3 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) p450 PF00067.17 EKG15510.1 - 6.3e-26 90.9 0.0 1.5e-25 89.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.13 EKG15512.1 - 2.5e-10 40.0 6.6 4.4e-10 39.2 4.6 1.4 1 0 0 1 1 1 1 MYND finger zf-HYPF PF07503.7 EKG15513.1 - 0.11 11.9 4.1 0.26 10.7 2.8 1.6 1 0 0 1 1 1 0 HypF finger zf-C2H2_4 PF13894.1 EKG15513.1 - 0.19 12.1 22.8 0.33 11.3 1.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2695 PF10905.3 EKG15513.1 - 0.79 9.4 3.8 53 3.6 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2695) Rubredoxin PF00301.15 EKG15513.1 - 0.95 9.3 5.7 1.3 8.9 1.8 2.5 2 0 0 2 2 2 0 Rubredoxin PAT1 PF09770.4 EKG15513.1 - 4.3 5.4 12.9 6.6 4.8 8.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-H2C2_2 PF13465.1 EKG15513.1 - 9.3 6.7 18.8 0.82 10.0 0.3 4.0 4 0 0 4 4 4 0 Zinc-finger double domain Transp_cyt_pur PF02133.10 EKG15517.1 - 1.5e-82 277.4 21.1 2.7e-72 243.7 7.5 2.0 1 1 1 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_S10 PF00450.17 EKG15518.1 - 6e-102 341.8 7.6 7.2e-102 341.6 5.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Tyrosinase PF00264.15 EKG15519.1 - 2e-48 165.4 1.6 2.7e-48 165.0 1.1 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase PIG-L PF02585.12 EKG15520.1 - 2.6e-26 92.6 0.2 4.2e-26 91.9 0.1 1.3 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase Lactamase_B PF00753.22 EKG15522.1 - 1e-27 97.0 2.8 1.5e-27 96.5 2.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG15522.1 - 5.2e-05 22.8 0.3 8.5e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EKG15522.1 - 0.0066 15.7 0.0 0.0095 15.2 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family EXOSC1 PF10447.4 EKG15523.1 - 2e-28 98.1 1.9 2.9e-28 97.6 1.3 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EKG15523.1 - 1.3e-11 43.5 0.0 2.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EKG15523.1 - 0.0052 16.8 1.3 0.085 12.9 0.9 2.5 1 1 0 1 1 1 1 S1 RNA binding domain HET PF06985.6 EKG15524.1 - 0.043 13.9 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) HET PF06985.6 EKG15525.1 - 1e-19 71.0 0.0 1.2e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLAC1 PF03595.12 EKG15526.1 - 4e-54 183.4 32.6 4.5e-54 183.3 22.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel F-box-like PF12937.2 EKG15527.1 - 0.0015 18.1 0.2 0.015 15.0 0.0 2.7 3 0 0 3 3 3 1 F-box-like Transp_cyt_pur PF02133.10 EKG15528.1 - 0.092 11.2 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_L22e PF01776.12 EKG15531.1 - 2.6e-49 165.8 0.7 3.1e-49 165.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Abhydrolase_3 PF07859.8 EKG15532.1 - 3.7e-61 206.3 0.0 4.8e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG15532.1 - 2.2e-06 27.4 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG15532.1 - 4.9e-06 26.5 3.3 9.7e-06 25.6 2.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG15532.1 - 0.00019 20.7 0.0 0.0016 17.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EKG15532.1 - 0.007 15.1 0.4 0.024 13.3 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2048 PF09752.4 EKG15532.1 - 0.038 12.8 0.0 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Chlorophyllase2 PF12740.2 EKG15532.1 - 0.061 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme FAD_binding_3 PF01494.14 EKG15533.1 - 4e-33 114.9 0.1 1.1e-32 113.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pirin PF02678.11 EKG15534.1 - 2e-28 98.3 0.0 4.1e-28 97.3 0.0 1.5 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EKG15534.1 - 4.1e-21 75.0 0.0 2.5e-20 72.4 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EKG15534.1 - 3.1e-05 23.3 0.0 0.0028 17.0 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Ribosomal_S8 PF00410.14 EKG15536.1 - 7.4e-23 80.8 0.0 3.3e-22 78.7 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 FHA PF00498.21 EKG15537.1 - 3e-06 27.2 0.0 7.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Ring_hydroxyl_A PF00848.14 EKG15538.1 - 0.075 12.6 1.5 0.1 12.2 0.6 1.5 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) O-FucT PF10250.4 EKG15538.1 - 0.095 11.7 0.4 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase FKBP_C PF00254.23 EKG15539.1 - 1.3e-32 111.7 0.0 1.5e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SseC PF04888.7 EKG15540.1 - 0.0056 16.0 1.7 0.22 10.8 1.0 2.2 2 0 0 2 2 2 2 Secretion system effector C (SseC) like family MFS_1 PF07690.11 EKG15541.1 - 2.2e-38 131.8 24.8 2.2e-38 131.8 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG15541.1 - 6.3e-07 27.9 9.2 0.001 17.3 1.4 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG15541.1 - 1.4e-05 23.8 13.4 1.4e-05 23.8 9.3 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter VanZ PF04892.7 EKG15541.1 - 0.049 13.5 0.3 0.049 13.5 0.2 2.4 2 0 0 2 2 2 0 VanZ like family zf-MYND PF01753.13 EKG15542.1 - 5e-09 35.8 15.2 5e-09 35.8 10.5 1.8 2 0 0 2 2 2 1 MYND finger DnaJ-X PF14308.1 EKG15543.1 - 2.1e-71 239.4 4.1 2.1e-71 239.4 2.8 3.0 4 1 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.26 EKG15543.1 - 3.5e-27 93.9 1.8 1e-26 92.4 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain IF4E PF01652.13 EKG15544.1 - 1.9e-59 199.9 0.1 2.2e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SQS_PSY PF00494.14 EKG15545.1 - 1.4e-39 135.9 0.0 1.8e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ank_2 PF12796.2 EKG15546.1 - 1.8e-59 198.0 12.9 2e-16 60.0 0.1 5.8 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EKG15546.1 - 3.2e-50 165.5 6.5 1.1e-07 31.2 0.0 8.6 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 EKG15546.1 - 2.6e-35 120.1 3.5 6.1e-08 32.9 0.0 7.1 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG15546.1 - 3.2e-35 116.6 0.7 5.7e-05 22.9 0.0 8.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EKG15546.1 - 1.3e-34 117.3 7.5 1.2e-07 31.7 0.1 7.5 2 1 5 7 7 7 7 Ankyrin repeats (many copies) TPR_12 PF13424.1 EKG15546.1 - 3.9e-11 42.7 12.6 1.1e-08 34.9 0.4 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG15546.1 - 1.9e-07 31.5 7.4 3.9e-06 27.3 2.4 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKG15546.1 - 4e-06 26.3 7.4 7.2e-06 25.5 4.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 EKG15546.1 - 4.1e-05 23.8 6.1 0.00062 20.0 0.6 3.2 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG15546.1 - 6.1e-05 22.6 16.5 0.002 17.8 1.8 3.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKG15546.1 - 0.00013 21.4 5.5 0.22 11.4 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG15546.1 - 0.00076 19.0 8.8 0.11 12.4 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKG15546.1 - 0.00078 19.4 1.0 0.44 10.8 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKG15546.1 - 0.0012 18.7 6.6 0.3 11.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG15546.1 - 0.0033 17.9 13.2 0.13 12.9 0.1 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKG15546.1 - 0.0044 17.3 8.8 0.0075 16.6 0.6 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EKG15546.1 - 0.035 14.2 8.2 0.96 9.6 5.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EKG15546.1 - 0.085 12.5 14.3 0.043 13.4 1.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EKG15546.1 - 8.7 6.2 11.4 13 5.7 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EKG15547.1 - 4.4e-60 203.5 17.1 3.8e-38 131.2 2.8 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EKG15547.1 - 6.5e-10 38.2 37.5 1.5e-06 27.2 12.7 2.6 2 2 0 2 2 2 2 Major Facilitator Superfamily Pil1 PF13805.1 EKG15548.1 - 3.5e-157 521.5 0.3 4.2e-157 521.2 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EKG15548.1 - 0.015 14.6 2.5 0.018 14.4 0.9 1.7 1 1 1 2 2 2 0 FAM92 protein SURF2 PF05477.6 EKG15548.1 - 0.083 12.0 0.6 0.14 11.2 0.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BMFP PF04380.8 EKG15548.1 - 0.31 11.1 2.9 19 5.4 0.0 3.1 3 0 0 3 3 3 0 Membrane fusogenic activity ABC_tran PF00005.22 EKG15549.1 - 2.8e-52 176.6 0.0 3.6e-31 108.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKG15549.1 - 5.7e-33 114.5 28.0 1.4e-18 67.2 8.3 3.2 3 1 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EKG15549.1 - 1.2e-09 37.7 1.0 0.00089 18.5 0.3 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKG15549.1 - 1e-05 25.9 0.2 0.00066 20.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EKG15549.1 - 1.1e-05 24.4 0.0 0.0034 16.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_21 PF13304.1 EKG15549.1 - 2e-05 24.6 0.6 1.9 8.3 0.0 4.1 2 2 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EKG15549.1 - 0.00017 21.6 1.6 0.24 11.3 0.6 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EKG15549.1 - 0.00018 20.9 0.0 0.31 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKG15549.1 - 0.00053 19.4 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG15549.1 - 0.00072 19.7 0.0 0.67 10.0 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EKG15549.1 - 0.00083 20.1 0.0 2.8 8.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKG15549.1 - 0.0011 18.8 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EKG15549.1 - 0.0017 17.8 0.8 0.71 9.2 0.0 2.8 2 1 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 EKG15549.1 - 0.0024 17.0 0.0 0.69 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EKG15549.1 - 0.0041 17.5 0.0 5.9 7.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EKG15549.1 - 0.0085 15.2 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 EKG15549.1 - 0.016 15.0 0.9 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 EKG15549.1 - 0.022 15.0 0.0 7.6 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EKG15549.1 - 0.027 14.0 0.0 4 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 EKG15549.1 - 0.043 14.0 0.4 4.6 7.4 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EKG15549.1 - 0.047 12.6 0.0 0.85 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EKG15549.1 - 0.06 13.1 0.4 1.3 8.7 0.0 3.3 3 0 0 3 3 2 0 Part of AAA domain Viral_helicase1 PF01443.13 EKG15549.1 - 0.089 12.2 0.0 0.46 9.9 0.0 2.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 EKG15549.1 - 0.12 11.8 0.0 19 4.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EKG15549.1 - 0.12 11.2 0.0 2.7 6.7 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain cobW PF02492.14 EKG15549.1 - 0.26 10.7 1.5 1 8.7 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EKG15549.1 - 0.3 10.3 0.1 8.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.7 EKG15549.1 - 0.34 10.5 2.5 0.87 9.2 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Pkinase PF00069.20 EKG15550.1 - 3.5e-17 62.4 0.0 4.6e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG15550.1 - 3.6e-08 32.7 0.0 4.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG15550.1 - 0.039 13.6 0.1 0.3 10.7 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG15550.1 - 0.06 12.2 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Fringe PF02434.11 EKG15551.1 - 5.2e-10 38.9 0.1 1.3e-06 27.8 0.0 3.1 2 1 0 2 2 2 2 Fringe-like PAN_4 PF14295.1 EKG15551.1 - 0.033 13.8 0.1 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 PAN domain RNA_pol_Rpb2_45 PF10385.4 EKG15551.1 - 0.15 11.9 0.0 3 7.7 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase beta subunit external 1 domain Sulfatase PF00884.18 EKG15552.1 - 1e-77 261.3 0.0 1.3e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EKG15552.1 - 0.00035 20.0 0.0 0.57 9.4 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EKG15552.1 - 0.067 13.4 0.2 1.4 9.1 0.1 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1289 PF06945.8 EKG15552.1 - 0.13 11.7 0.1 0.28 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) DUF229 PF02995.12 EKG15552.1 - 0.15 10.4 0.0 0.27 9.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Sugar_tr PF00083.19 EKG15553.1 - 1.9e-83 280.5 9.8 2.3e-83 280.2 6.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15553.1 - 1.1e-17 63.7 8.1 1.1e-17 63.7 5.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldolase_2 PF10120.4 EKG15554.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative aldolase TPR_12 PF13424.1 EKG15555.1 - 2.8e-27 94.4 22.5 2.5e-10 40.1 0.2 5.0 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EKG15555.1 - 1.2e-19 69.4 20.7 4.6e-05 23.2 0.1 8.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 EKG15555.1 - 6.1e-13 47.5 18.1 0.022 14.5 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKG15555.1 - 8.8e-13 47.2 11.4 0.0045 16.5 0.0 6.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKG15555.1 - 4.1e-08 32.5 18.8 0.06 13.2 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EKG15555.1 - 1.2e-06 28.6 12.3 5.1 8.0 0.1 7.2 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG15555.1 - 2e-06 27.1 12.7 0.61 10.0 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKG15555.1 - 2e-06 27.3 18.9 0.064 12.9 0.1 4.9 4 3 1 5 5 5 4 TPR repeat TPR_19 PF14559.1 EKG15555.1 - 0.048 14.0 14.6 8.3 6.8 0.6 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF845 PF05820.6 EKG15555.1 - 0.11 12.2 0.0 0.83 9.4 0.0 2.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF845) TPR_6 PF13174.1 EKG15555.1 - 2.3 8.8 13.5 7.3 7.2 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKG15555.1 - 3 8.6 16.1 10 6.9 0.3 4.9 5 1 1 6 6 5 0 Tetratricopeptide repeat TOH_N PF12549.3 EKG15556.1 - 3.8 7.2 9.3 9.3 5.9 0.0 3.9 3 1 1 4 4 4 0 Tyrosine hydroxylase N terminal Choline_transpo PF04515.7 EKG15558.1 - 2e-104 348.9 19.5 2e-104 348.9 13.5 2.3 2 1 0 2 2 2 1 Plasma-membrane choline transporter Cyto_ox_2 PF02322.10 EKG15558.1 - 0.0003 20.0 11.7 0.0003 20.0 8.1 3.5 2 2 2 4 4 4 2 Cytochrome oxidase subunit II Abhydrolase_2 PF02230.11 EKG15559.1 - 9.7e-13 48.0 0.0 1e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EKG15559.1 - 5.8e-10 39.4 0.4 1.7e-06 28.0 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG15559.1 - 1.5e-09 37.7 0.0 3.3e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EKG15559.1 - 5.1e-09 35.7 0.0 6.7e-05 22.2 0.0 3.3 2 1 1 3 3 3 2 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EKG15559.1 - 6.4e-08 32.0 0.5 0.00087 18.5 0.1 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EKG15559.1 - 9.3e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 EKG15559.1 - 5.5e-06 25.9 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 2 Putative esterase Abhydrolase_3 PF07859.8 EKG15559.1 - 0.0078 15.8 0.1 2 7.9 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.9 EKG15559.1 - 0.013 14.7 0.1 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_1 PF00561.15 EKG15559.1 - 0.076 12.5 0.2 1.3 8.5 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2235 PF09994.4 EKG15560.1 - 5.4e-39 134.2 0.0 4.6e-37 127.8 0.0 2.3 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_M24 PF00557.19 EKG15561.1 - 2.3e-55 187.4 0.0 3.2e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EKG15561.1 - 1.9e-28 98.5 0.0 5.6e-28 97.0 0.0 1.8 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain KRE9 PF05390.6 EKG15562.1 - 3.2e-20 72.4 10.3 8e-20 71.1 7.1 1.6 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EKG15562.1 - 4.9e-11 42.9 2.4 9.4e-11 42.0 0.1 2.4 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cyclin PF08613.6 EKG15563.1 - 1.2e-31 110.1 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin TMEM138 PF14935.1 EKG15564.1 - 0.13 12.5 5.7 0.23 11.8 0.6 2.3 2 0 0 2 2 2 0 Transmembrane protein 138 adh_short PF00106.20 EKG15565.1 - 1.7e-26 93.1 0.3 3e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG15565.1 - 2.9e-11 43.6 0.0 4.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG15565.1 - 1e-08 35.0 0.5 2.4e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 EKG15565.1 - 2.4e-06 26.8 0.0 3.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EKG15565.1 - 0.0031 17.5 0.4 0.029 14.3 0.1 2.5 2 1 1 3 3 3 1 NADH(P)-binding NmrA PF05368.8 EKG15565.1 - 0.0038 16.5 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 EKG15565.1 - 0.006 16.3 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG15565.1 - 0.045 13.1 0.1 0.16 11.4 0.0 1.9 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family Mob1_phocein PF03637.12 EKG15566.1 - 1.2e-26 93.4 0.3 1.8e-26 92.8 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family YqeY PF09424.5 EKG15568.1 - 1.4e-22 80.0 5.9 2e-22 79.6 4.1 1.2 1 0 0 1 1 1 1 Yqey-like protein DEAD_assoc PF08494.6 EKG15568.1 - 0.093 12.4 0.6 0.13 12.0 0.4 1.2 1 0 0 1 1 1 0 DEAD/H associated Nucleoporin_C PF03177.9 EKG15569.1 - 7.6e-124 414.3 6.0 9.8e-124 414.0 4.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EKG15569.1 - 1e-81 274.8 0.8 1.5e-81 274.3 0.5 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF1179 PF06678.6 EKG15569.1 - 0.95 9.7 2.4 2.7 8.3 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) eIF3g PF12353.3 EKG15573.1 - 0.028 14.3 2.4 0.035 14.0 1.4 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Ribosomal_L36 PF00444.13 EKG15573.1 - 0.37 10.8 3.1 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L36 DUF4473 PF14747.1 EKG15574.1 - 0.079 13.1 0.0 0.16 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) BRO1 PF03097.13 EKG15575.1 - 2.4e-135 451.1 0.8 2.4e-135 451.1 0.6 2.3 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EKG15575.1 - 8.2e-101 336.8 15.3 8.2e-101 336.8 10.6 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.7 EKG15575.1 - 0.0052 15.9 1.0 0.61 9.2 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF416) DUF2383 PF09537.5 EKG15575.1 - 0.032 14.4 10.9 1.7 8.9 0.0 5.4 6 0 0 6 6 6 0 Domain of unknown function (DUF2383) Prefoldin_3 PF13758.1 EKG15575.1 - 1.2 9.0 10.4 3 7.6 0.6 3.2 3 0 0 3 3 3 0 Prefoldin subunit CTDII PF01556.13 EKG15576.1 - 8.4e-28 96.0 4.7 9.4e-23 79.9 0.5 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EKG15576.1 - 5e-23 80.6 2.8 1.1e-22 79.4 2.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EKG15576.1 - 1.5e-09 37.7 21.6 2.8e-09 36.9 15.0 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EKG15576.1 - 8.4 6.1 9.8 23 4.7 1.0 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family SAP30_Sin3_bdg PF13867.1 EKG15577.1 - 1.8e-08 34.1 0.2 3e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 V_ATPase_I PF01496.14 EKG15579.1 - 0.0077 14.1 9.4 0.01 13.7 6.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4055 PF13264.1 EKG15579.1 - 0.23 11.5 3.5 0.45 10.6 1.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) YlqD PF11068.3 EKG15579.1 - 0.56 10.2 12.3 0.23 11.4 3.8 2.7 1 1 1 3 3 3 0 YlqD protein Thymidylat_synt PF00303.14 EKG15580.1 - 9.7e-117 388.7 0.0 1.1e-116 388.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase BLOC1_2 PF10046.4 EKG15581.1 - 0.0051 16.9 0.1 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EKG15581.1 - 0.1 12.5 0.1 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 EKG15581.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Prefoldin subunit PALP PF00291.20 EKG15582.1 - 6.6e-60 202.9 0.1 8.3e-60 202.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EKG15582.1 - 2.9e-11 42.9 0.0 4.4e-09 35.9 0.0 2.8 2 0 0 2 2 2 2 CBS domain EAF PF09816.4 EKG15582.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor Zn_clus PF00172.13 EKG15586.1 - 0.00014 21.7 6.8 0.00022 21.0 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bacillus_HBL PF05791.6 EKG15588.1 - 0.0026 17.1 0.8 0.0047 16.3 0.1 1.7 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) FlxA PF14282.1 EKG15588.1 - 0.63 10.0 3.9 0.91 9.4 1.3 2.0 1 1 0 2 2 2 0 FlxA-like protein DUF3450 PF11932.3 EKG15588.1 - 1 8.6 12.3 0.71 9.0 1.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF3573 PF12097.3 EKG15589.1 - 0.0049 15.5 2.0 0.0076 14.9 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) Glyco_hydro_71 PF03659.9 EKG15592.1 - 6.4e-20 70.9 3.1 7.7e-20 70.7 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.9 EKG15593.1 - 5.9e-16 57.9 0.0 8.5e-16 57.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Paramyxo_PCT PF14320.1 EKG15593.1 - 0.051 12.4 1.3 0.1 11.4 0.1 1.8 1 1 1 2 2 2 0 Phosphoprotein P region PCT disordered Transketolase_N PF00456.16 EKG15594.1 - 6.2e-148 492.0 0.0 9.9e-148 491.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EKG15594.1 - 9.7e-46 155.4 0.0 1.6e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EKG15594.1 - 6.8e-15 55.0 0.0 1.3e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EKG15594.1 - 3.5e-06 26.1 0.0 0.00012 21.1 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EKG15594.1 - 4.2e-05 22.4 0.1 6.9e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF543 PF04418.7 EKG15595.1 - 1.4e-27 95.3 0.0 1.6e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DUF2456 PF10445.4 EKG15595.1 - 0.15 11.9 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Urb2 PF10441.4 EKG15596.1 - 1.2e-48 165.6 0.0 5.6e-48 163.4 0.0 2.2 1 0 0 1 1 1 1 Urb2/Npa2 family Orbi_VP3 PF01700.11 EKG15597.1 - 0.042 11.2 0.0 0.053 10.9 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Methyltransf_23 PF13489.1 EKG15598.1 - 0.0048 16.6 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15598.1 - 0.033 14.6 0.0 0.088 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EKG15598.1 - 0.036 14.4 0.0 0.066 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Xan_ur_permease PF00860.15 EKG15599.1 - 2.9e-26 91.8 28.2 4.8e-25 87.8 18.7 2.6 2 1 0 2 2 2 1 Permease family Ebp2 PF05890.7 EKG15600.1 - 2e-93 312.6 21.0 2e-93 312.6 14.5 2.2 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 HSBP1 PF06825.7 EKG15601.1 - 9.6e-17 60.3 0.6 1.1e-16 60.0 0.4 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EKG15601.1 - 0.00013 21.2 0.9 0.021 14.1 0.2 2.1 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 EKG15601.1 - 0.0032 17.6 0.5 0.0041 17.3 0.3 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.10 EKG15601.1 - 0.023 13.8 0.0 0.025 13.8 0.0 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2884 PF11101.3 EKG15601.1 - 0.04 13.2 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) MMS22L_N PF14910.1 EKG15601.1 - 0.056 11.6 0.0 0.063 11.5 0.0 1.0 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, N-terminal Baculo_PEP_C PF04513.7 EKG15601.1 - 0.057 13.2 0.1 0.068 13.0 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SnAPC_2_like PF11035.3 EKG15601.1 - 0.075 12.4 0.0 0.084 12.3 0.0 1.0 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2-like DUF1664 PF07889.7 EKG15601.1 - 0.11 12.2 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Transp_cyt_pur PF02133.10 EKG15602.1 - 2.3e-147 491.1 40.9 2.7e-147 490.9 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans_2 PF11951.3 EKG15603.1 - 0.016 13.8 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cupin_2 PF07883.6 EKG15604.1 - 7.6e-07 28.5 0.0 1.5e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EKG15604.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) tRNA_anti-codon PF01336.20 EKG15606.1 - 0.0013 18.5 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NAD_binding_5 PF07994.7 EKG15607.1 - 7e-111 370.4 0.1 8.7e-111 370.1 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EKG15607.1 - 8.5e-46 154.3 0.6 1.6e-45 153.5 0.4 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase LIM PF00412.17 EKG15608.1 - 3e-20 72.0 26.2 5.9e-12 45.4 3.8 3.0 3 0 0 3 3 3 2 LIM domain Glyco_hydro_3 PF00933.16 EKG15610.1 - 1.7e-48 165.1 0.0 2.4e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG15610.1 - 7e-31 107.4 0.0 9.2e-28 97.2 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG15610.1 - 1.1e-15 57.2 1.0 2.5e-15 56.1 0.7 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EKG15610.1 - 1.4e-08 34.5 0.1 8.4e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 PA14 domain Glyco_hydro_92 PF07971.7 EKG15611.1 - 3.4e-166 553.8 0.6 4.3e-166 553.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Methyltransf_23 PF13489.1 EKG15612.1 - 1.5e-13 50.8 0.0 1.9e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15612.1 - 4.5e-11 43.3 0.0 9.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15612.1 - 1.3e-10 41.0 0.0 1.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG15612.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG15612.1 - 2.5e-09 37.4 0.0 4.1e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15612.1 - 7.1e-09 36.0 0.0 2.5e-08 34.2 0.0 2.0 2 1 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 EKG15612.1 - 0.0063 16.0 0.1 0.022 14.2 0.0 1.8 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EKG15612.1 - 0.0083 15.2 0.1 0.017 14.2 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EKG15612.1 - 0.018 15.0 0.2 0.072 13.1 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EKG15612.1 - 0.039 13.1 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EKG15612.1 - 0.07 12.8 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_7 PF03492.10 EKG15612.1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase DUF2731 PF10806.3 EKG15613.1 - 3.5e-06 27.2 0.2 9.1e-06 25.9 0.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2731) GST_C_2 PF13410.1 EKG15613.1 - 0.00045 20.0 1.8 0.00054 19.8 0.4 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG15613.1 - 0.00051 20.4 0.1 0.00076 19.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.4 EKG15613.1 - 0.0037 17.4 0.0 0.0072 16.5 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein A_deaminase PF00962.17 EKG15615.1 - 4.9e-41 140.7 0.0 8.4e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF3285 PF11688.3 EKG15615.1 - 0.014 15.0 0.7 0.026 14.1 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) RNase_PH PF01138.16 EKG15617.1 - 8.8e-08 32.5 0.1 1.7e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 UQ_con PF00179.21 EKG15618.1 - 2.2e-36 124.3 0.0 2.7e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.6 EKG15618.1 - 0.0057 16.1 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 EKG15618.1 - 0.033 14.0 0.1 0.056 13.3 0.1 1.7 1 1 0 1 1 1 0 RWD domain NmrA PF05368.8 EKG15619.1 - 4e-07 29.5 0.0 8.6e-07 28.4 0.0 1.5 1 1 1 2 2 2 1 NmrA-like family Ras PF00071.17 EKG15620.1 - 6.1e-57 191.5 0.1 7.8e-57 191.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG15620.1 - 3.3e-19 69.5 0.0 4.9e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG15620.1 - 3.2e-12 46.0 0.0 3.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKG15620.1 - 3e-07 30.4 0.0 3.9e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EKG15620.1 - 1.1e-06 28.0 0.0 1.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKG15620.1 - 1.4e-06 27.9 0.0 3.2e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EKG15620.1 - 0.00025 20.6 0.4 0.0082 15.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EKG15620.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKG15620.1 - 0.0012 18.1 0.1 0.0022 17.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EKG15620.1 - 0.003 17.0 0.1 0.097 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EKG15620.1 - 0.0046 16.5 0.2 0.0082 15.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EKG15620.1 - 0.0049 16.6 0.1 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EKG15620.1 - 0.0057 16.6 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.13 EKG15620.1 - 0.0064 15.5 0.1 0.042 12.8 0.0 2.1 2 0 0 2 2 2 1 Septin SRPRB PF09439.5 EKG15620.1 - 0.0071 15.5 0.0 0.0089 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 EKG15620.1 - 0.0078 15.6 0.0 0.034 13.5 0.0 1.8 1 1 2 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EKG15620.1 - 0.0082 15.6 0.2 0.018 14.4 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 EKG15620.1 - 0.0085 15.8 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MobB PF03205.9 EKG15620.1 - 0.024 14.3 0.1 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EKG15620.1 - 0.04 13.6 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.13 EKG15620.1 - 0.075 12.3 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 EKG15620.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EKG15620.1 - 0.13 11.1 0.1 0.54 9.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain DUF914 PF06027.7 EKG15621.1 - 9.6e-08 31.2 6.6 2.3e-06 26.7 3.6 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EKG15621.1 - 1.8e-07 31.2 31.8 3e-06 27.2 4.6 3.1 3 1 1 4 4 4 2 EamA-like transporter family UAA PF08449.6 EKG15621.1 - 4.9e-06 25.6 8.8 4.9e-06 25.6 6.1 1.4 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 EKG15621.1 - 3.2e-05 23.6 25.3 0.0071 15.9 3.4 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EKG15621.1 - 0.00014 22.0 5.6 0.00014 22.0 3.9 3.7 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EKG15621.1 - 0.45 10.3 10.2 2.4 7.9 0.6 3.4 4 0 0 4 4 4 0 Uncharacterised protein family UPF0546 TruB_N PF01509.13 EKG15622.1 - 2.3e-42 144.6 0.2 3.8e-41 140.7 0.0 2.4 2 1 1 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) DNMT1-RFD PF12047.3 EKG15623.1 - 9.6e-05 22.1 0.0 0.00047 19.8 0.0 2.0 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Fungal_trans PF04082.13 EKG15624.1 - 0.0034 16.2 2.1 0.0064 15.4 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Phage_int_SAM_5 PF13102.1 EKG15624.1 - 0.15 12.0 0.1 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Phage integrase SAM-like domain Band_7 PF01145.20 EKG15625.1 - 5.1e-25 88.4 5.0 5.1e-25 88.4 3.5 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family GFA PF04828.9 EKG15625.1 - 7.2e-11 41.8 0.0 1.5e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GatB_Yqey PF02637.13 EKG15625.1 - 0.047 13.4 3.2 0.1 12.3 2.2 1.5 1 1 0 1 1 1 0 GatB domain UcrQ PF02939.11 EKG15626.1 - 3.3e-32 110.1 0.2 3.8e-32 109.9 0.2 1.1 1 0 0 1 1 1 1 UcrQ family EF-hand_5 PF13202.1 EKG15627.1 - 0.021 14.1 0.3 0.036 13.4 0.2 1.3 1 0 0 1 1 1 0 EF hand HTH_19 PF12844.2 EKG15627.1 - 0.031 14.3 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3696 PF12476.3 EKG15627.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) CFEM PF05730.6 EKG15628.1 - 0.00013 21.7 5.9 0.00026 20.7 4.1 1.4 1 0 0 1 1 1 1 CFEM domain Rax2 PF12768.2 EKG15628.1 - 0.022 13.9 0.1 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DAP10 PF07213.6 EKG15628.1 - 0.033 13.9 0.6 0.099 12.4 0.4 1.8 1 0 0 1 1 1 0 DAP10 membrane protein Adeno_E3_CR2 PF02439.10 EKG15628.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 EKG15628.1 - 0.34 10.5 0.0 0.54 9.8 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 EKG15628.1 - 1.7 8.3 13.9 0.034 13.8 3.3 2.8 3 1 0 3 3 3 0 TMEM154 protein family DUF1212 PF06738.7 EKG15629.1 - 8.1e-51 172.2 16.9 2.2e-50 170.8 0.1 2.9 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EKG15629.1 - 2e-23 82.7 33.7 4.5e-16 58.9 1.6 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3815) G-alpha PF00503.15 EKG15631.1 - 1.6e-133 445.1 2.2 2e-133 444.8 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EKG15631.1 - 3.3e-15 55.7 2.4 2e-10 40.1 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EKG15631.1 - 0.00015 21.2 0.0 0.00067 19.1 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EKG15631.1 - 0.0013 19.2 0.1 3 8.3 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EKG15631.1 - 0.003 16.7 2.7 0.16 11.0 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EKG15631.1 - 0.0098 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EKG15631.1 - 0.026 13.9 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 EKG15631.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 EKG15631.1 - 0.1 12.5 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EKG15631.1 - 0.12 11.7 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family HAD PF12710.2 EKG15632.1 - 7.4e-10 39.3 0.1 1.1e-09 38.7 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EKG15632.1 - 0.0017 17.6 0.0 0.01 15.1 0.0 2.2 2 1 1 3 3 3 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.7 EKG15632.1 - 0.005 16.0 0.0 0.38 9.8 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 EKG15632.1 - 0.069 13.5 0.1 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase PS_Dcarbxylase PF02666.10 EKG15633.1 - 4e-50 169.9 0.0 5.9e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EKG15633.1 - 3.9e-35 119.5 0.1 3.8e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 C2 domain DUF2315 PF10231.4 EKG15633.1 - 0.015 15.1 0.1 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) APO_RNA-bind PF05634.6 EKG15633.1 - 0.026 13.6 1.7 0.06 12.5 1.2 1.6 1 0 0 1 1 1 0 APO RNA-binding EF-hand_7 PF13499.1 EKG15633.1 - 0.058 13.5 0.3 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair Ureide_permease PF07168.6 EKG15633.1 - 0.28 9.8 0.4 0.61 8.7 0.3 1.5 1 0 0 1 1 1 0 Ureide permease CDC45 PF02724.9 EKG15633.1 - 1.8 6.5 7.8 2.8 5.8 5.4 1.2 1 0 0 1 1 1 0 CDC45-like protein MIS13 PF08202.6 EKG15634.1 - 8.2e-47 159.7 4.2 5.5e-46 157.0 2.9 2.1 1 1 0 1 1 1 1 Mis12-Mtw1 protein family DUF904 PF06005.7 EKG15634.1 - 0.033 14.4 1.3 0.09 13.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) POT1 PF02765.12 EKG15636.1 - 8.9e-07 28.9 0.8 4.1e-06 26.7 0.0 2.3 2 1 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.18 EKG15637.1 - 6.2e-96 311.3 11.1 1.1e-13 50.4 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EKG15637.1 - 2.6e-25 88.5 0.3 2.6e-10 40.4 0.0 5.6 1 1 5 6 6 6 6 HEAT repeats IBB PF01749.15 EKG15637.1 - 1.9e-22 79.2 0.7 3.4e-22 78.4 0.5 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EKG15637.1 - 3e-20 70.4 1.4 6.7e-06 25.7 0.0 7.4 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 EKG15637.1 - 1.1e-19 70.3 9.8 5.9e-09 36.1 0.0 6.2 5 1 2 7 7 7 3 HEAT-like repeat Arm_2 PF04826.8 EKG15637.1 - 7.6e-12 44.8 0.0 0.0024 17.0 0.0 4.2 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EKG15637.1 - 5.5e-07 28.2 0.0 3e-05 22.5 0.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EKG15637.1 - 0.0002 21.2 0.0 0.97 9.3 0.0 4.3 3 2 2 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EKG15637.1 - 0.0068 14.7 0.0 0.22 9.7 0.0 2.5 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EKG15637.1 - 0.014 15.8 6.1 0.53 10.8 0.1 4.7 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.1 EKG15637.1 - 0.022 14.6 4.3 1.7 8.6 0.0 4.6 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 MAP65_ASE1 PF03999.7 EKG15638.1 - 5.2e-75 253.2 9.1 5.2e-75 253.2 6.3 2.2 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) RPW8 PF05659.6 EKG15638.1 - 0.091 12.3 0.4 0.47 9.9 0.1 2.3 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spectrin PF00435.16 EKG15638.1 - 0.11 12.7 19.9 0.3 11.4 0.7 4.9 4 1 0 4 4 4 0 Spectrin repeat TMCO5 PF14992.1 EKG15638.1 - 0.81 8.7 11.8 2.2 7.3 1.3 3.2 1 1 3 4 4 4 0 TMCO5 family BioT2 PF15368.1 EKG15639.1 - 0.012 15.3 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Spermatogenesis family BioT2 PTPLA PF04387.9 EKG15640.1 - 3.1e-54 182.8 7.2 4.9e-54 182.1 5.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA zf-RING_5 PF14634.1 EKG15641.1 - 0.015 15.0 7.5 0.027 14.1 5.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG15641.1 - 0.034 14.1 2.2 0.034 14.1 1.6 1.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PhnA_Zn_Ribbon PF08274.7 EKG15641.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-C3HC4 PF00097.20 EKG15641.1 - 0.25 11.0 3.2 0.59 9.8 2.2 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG15641.1 - 0.28 11.0 3.1 0.51 10.2 2.2 1.5 1 0 0 1 1 1 0 Ring finger domain Prp19 PF08606.6 EKG15642.1 - 1.4e-33 114.4 2.3 1.4e-33 114.4 1.6 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like WD40 PF00400.27 EKG15642.1 - 3.2e-13 49.0 0.3 0.00034 20.3 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EKG15642.1 - 8.5e-05 22.3 0.2 0.0011 18.6 0.1 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EKG15642.1 - 0.0012 17.1 0.0 0.0088 14.3 0.0 2.2 2 1 2 4 4 4 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EKG15642.1 - 0.0079 15.0 0.0 0.028 13.2 0.0 1.7 1 1 1 2 2 2 1 Coatomer WD associated region PQQ PF01011.16 EKG15642.1 - 0.07 12.6 0.1 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat DUF3312 PF11768.3 EKG15642.1 - 0.095 10.9 0.0 0.15 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) LDB19 PF13002.2 EKG15643.1 - 7.4e-52 175.6 0.2 1.3e-51 174.8 0.1 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EKG15643.1 - 1.8e-06 27.8 0.0 8.2e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 EKG15643.1 - 0.038 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein ketoacyl-synt PF00109.21 EKG15644.1 - 1.3e-65 221.3 0.4 2.2e-65 220.6 0.3 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG15644.1 - 1.1e-53 181.6 0.1 2.7e-53 180.3 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EKG15644.1 - 8.2e-45 153.2 0.0 1.5e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EKG15644.1 - 3.2e-40 137.7 0.1 1.5e-39 135.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG15644.1 - 2.6e-32 111.1 0.3 5.2e-32 110.1 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EKG15644.1 - 3.9e-26 92.1 0.1 1.6e-24 86.8 0.0 2.8 2 1 1 3 3 3 1 Acyl transferase domain ADH_zinc_N PF00107.21 EKG15644.1 - 2.2e-20 72.4 0.0 9.4e-20 70.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EKG15644.1 - 2.5e-17 63.1 0.0 8.3e-17 61.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EKG15644.1 - 2.9e-14 54.0 0.0 1.8e-13 51.5 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EKG15644.1 - 4.9e-14 52.3 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15644.1 - 2.8e-12 46.4 0.0 9.3e-12 44.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG15644.1 - 4.7e-09 36.6 0.0 1.7e-08 34.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15644.1 - 1.5e-08 35.2 0.0 4.4e-07 30.4 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG15644.1 - 3.3e-07 29.6 0.0 7.3e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.7 EKG15644.1 - 4.5e-07 29.6 0.0 1.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EKG15644.1 - 0.0014 17.7 0.3 0.0026 16.8 0.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.1 EKG15644.1 - 0.0058 16.4 0.1 0.048 13.4 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NodS PF05401.6 EKG15644.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) DUF915 PF06028.6 EKG15644.1 - 0.082 11.9 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) FMO-like PF00743.14 EKG15645.1 - 1.1e-30 106.3 0.0 1.6e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EKG15645.1 - 1.3e-11 44.9 0.1 5.8e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG15645.1 - 8.2e-09 34.8 0.2 3.1e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EKG15645.1 - 0.0015 18.4 0.0 0.031 14.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4449 PF14613.1 EKG15647.1 - 3.4e-67 225.4 7.3 3.4e-67 225.4 5.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) CRCB PF02537.10 EKG15648.1 - 3e-29 101.2 20.6 2e-20 72.8 3.4 3.7 4 0 0 4 4 4 3 CrcB-like protein IL11 PF07400.6 EKG15648.1 - 0.08 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Interleukin 11 UPRTase PF14681.1 EKG15649.1 - 1.1e-55 188.0 0.0 1.2e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EKG15649.1 - 9.7e-09 35.0 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RCC1_2 PF13540.1 EKG15650.1 - 5.9e-13 48.0 9.1 0.00035 20.1 0.0 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EKG15650.1 - 4.3e-07 30.0 0.0 0.0043 17.2 0.0 3.9 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat PalH PF08733.5 EKG15651.1 - 2.2e-98 329.2 0.3 2.8e-98 328.9 0.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 PX PF00787.19 EKG15652.1 - 8.8e-17 60.9 0.1 1.9e-16 59.8 0.1 1.5 1 0 0 1 1 1 1 PX domain Cullin_binding PF03556.10 EKG15653.1 - 5.7e-31 107.0 3.3 8.6e-31 106.5 2.3 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EKG15653.1 - 3.9e-11 42.2 0.2 8.3e-11 41.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EKG15653.1 - 0.18 11.7 0.3 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 UBA/TS-N domain Bestrophin PF01062.16 EKG15654.1 - 3.2e-43 147.7 0.0 4.5e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel GCV_T PF01571.16 EKG15655.1 - 6.9e-17 61.5 0.0 6.4e-16 58.3 0.0 2.1 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EKG15655.1 - 0.00046 20.1 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DCP2 PF05026.8 EKG15656.1 - 1.5e-35 120.9 1.5 2.9e-35 120.0 1.1 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EKG15656.1 - 5.3e-16 58.4 0.0 1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 EKG15657.1 - 1.4e-27 95.6 0.1 1.9e-27 95.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) zf-LITAF-like PF10601.4 EKG15657.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain DUF2392 PF10288.4 EKG15659.1 - 4.4e-29 100.9 0.0 6.7e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Lung_7-TM_R PF06814.8 EKG15660.1 - 5.5e-70 235.6 13.9 6.6e-70 235.3 9.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 EKG15660.1 - 0.14 12.3 19.3 0.55 10.4 0.6 3.5 1 1 1 3 3 3 0 PrgI family protein 60KD_IMP PF02096.15 EKG15660.1 - 1.1 8.8 5.1 2.7 7.5 3.3 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein EphA2_TM PF14575.1 EKG15662.1 - 0.0082 16.5 0.0 0.0092 16.3 0.0 1.3 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 EKG15662.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Protocadherin IncA PF04156.9 EKG15662.1 - 0.033 13.8 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 IncA protein DUF1049 PF06305.6 EKG15662.1 - 0.036 13.5 0.1 0.056 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) MFS_1 PF07690.11 EKG15663.1 - 1.7e-32 112.4 14.1 2.1e-32 112.1 9.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15663.1 - 1e-13 50.6 4.8 1.3e-13 50.3 3.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EKG15663.1 - 0.0017 16.6 1.3 0.0021 16.3 0.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EKG15663.1 - 0.0024 16.0 0.4 0.0031 15.7 0.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EKG15663.1 - 0.12 10.4 2.7 0.068 11.2 0.1 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.17 EKG15664.1 - 6.3e-38 130.4 0.0 8.5e-38 130.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sulfotransfer_3 PF13469.1 EKG15665.1 - 0.00021 22.2 0.3 0.00028 21.8 0.2 1.2 1 0 0 1 1 1 1 Sulfotransferase family Sfi1 PF08457.5 EKG15667.1 - 9e-98 328.1 80.4 9e-98 328.1 55.8 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 EKG15669.1 - 1.4e-222 739.9 0.0 3.4e-222 738.7 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EKG15669.1 - 1.9e-25 89.4 0.0 3.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EKG15669.1 - 5.9e-18 64.6 0.2 1.5e-06 27.1 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EKG15669.1 - 0.059 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.9 EKG15670.1 - 7.6e-103 343.5 0.0 2e-102 342.1 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EKG15670.1 - 1.1e-07 31.8 31.7 1.1e-07 31.8 22.0 4.6 1 1 3 4 4 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm PF00514.18 EKG15670.1 - 0.0015 18.2 1.8 0.79 9.6 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat COG2 PF06148.6 EKG15670.1 - 0.011 15.5 2.7 0.011 15.5 1.9 5.4 3 1 4 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 HEAT PF02985.17 EKG15670.1 - 0.013 15.5 6.8 2 8.7 0.1 4.7 4 0 0 4 4 4 0 HEAT repeat L27_N PF09060.5 EKG15670.1 - 0.22 11.3 0.0 0.22 11.3 0.0 3.6 4 0 0 4 4 4 0 L27_N DUF3584 PF12128.3 EKG15670.1 - 0.68 7.1 73.1 0.9 6.7 12.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) AAA_27 PF13514.1 EKG15670.1 - 0.8 7.3 66.3 1.7 6.2 45.9 1.4 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EKG15670.1 - 0.84 9.1 78.6 0.01 15.4 21.8 3.6 1 1 1 3 3 3 0 IncA protein ATG16 PF08614.6 EKG15670.1 - 1.9 8.2 69.7 0.92 9.2 11.5 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EKG15670.1 - 2 7.4 28.6 0.068 12.3 3.5 3.8 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EKG15670.1 - 3.4 6.2 61.2 0.03 13.0 12.7 4.1 1 1 3 4 4 4 0 Spc7 kinetochore protein Tropomyosin PF00261.15 EKG15670.1 - 3.8 6.5 76.3 0.1 11.6 22.2 3.2 1 1 1 3 3 3 0 Tropomyosin Filament PF00038.16 EKG15670.1 - 9.1 5.6 66.4 8.1 5.8 29.1 3.0 1 1 1 2 2 2 0 Intermediate filament protein XRN_N PF03159.13 EKG15671.1 - 4.4e-107 356.8 1.1 4.7e-107 356.7 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EKG15671.1 - 0.00019 21.2 4.0 0.00035 20.3 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EKG15671.1 - 0.01 15.5 2.5 0.019 14.6 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EKG15671.1 - 0.26 10.8 4.7 0.64 9.5 3.2 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PARP PF00644.15 EKG15672.1 - 2.3e-12 46.8 0.9 4.3e-12 45.9 0.5 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EKG15672.1 - 6.1e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG15672.1 - 0.00093 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKG15672.1 - 0.14 12.0 0.0 0.65 9.9 0.0 2.0 2 0 0 2 2 2 0 RWD domain DUF2457 PF10446.4 EKG15672.1 - 6.1 5.4 8.0 3.7 6.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) GrpE PF01025.14 EKG15673.1 - 0.036 13.6 1.7 0.048 13.1 0.4 1.8 2 0 0 2 2 2 0 GrpE COG5 PF10392.4 EKG15673.1 - 0.062 13.2 0.2 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF904 PF06005.7 EKG15673.1 - 0.21 11.8 1.9 3.4 8.0 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) SPX PF03105.14 EKG15673.1 - 0.25 11.1 2.0 0.47 10.1 1.4 1.6 1 1 0 1 1 1 0 SPX domain FliT PF05400.8 EKG15673.1 - 0.45 10.9 3.8 17 5.8 0.2 3.2 2 1 1 3 3 3 0 Flagellar protein FliT Sugar_tr PF00083.19 EKG15674.1 - 1.3e-12 47.0 0.0 1.6e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TRAM_LAG1_CLN8 PF03798.11 EKG15675.1 - 3e-46 157.4 7.6 5.1e-46 156.7 5.3 1.4 1 0 0 1 1 1 1 TLC domain PPO1_KFDV PF12143.3 EKG15675.1 - 0.26 11.1 3.0 0.67 9.8 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF_B2219) BTB PF00651.26 EKG15677.1 - 0.013 15.4 0.0 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain tRNA-synt_2b PF00587.20 EKG15678.1 - 2.1e-22 79.5 0.0 3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EKG15678.1 - 1.1e-16 60.8 1.5 2e-16 59.9 1.1 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain LptE PF04390.7 EKG15678.1 - 0.079 12.7 0.1 4.8 6.9 0.0 2.8 2 1 1 3 3 3 0 Lipopolysaccharide-assembly Diphtheria_T PF02764.9 EKG15678.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Diphtheria toxin, T domain GST_N_3 PF13417.1 EKG15679.1 - 3e-13 49.7 0.1 7.6e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG15679.1 - 7.3e-10 38.7 0.1 1.8e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG15679.1 - 1.8e-08 34.1 1.5 7.9e-08 32.0 0.8 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3328 PF11807.3 EKG15680.1 - 1.2e-56 191.7 0.2 1.5e-56 191.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NACHT PF05729.7 EKG15684.1 - 0.003 17.2 0.0 0.0078 15.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EKG15684.1 - 0.014 15.4 0.6 0.15 12.0 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain ZZ PF00569.12 EKG15684.1 - 0.068 12.7 12.4 0.15 11.5 8.6 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type AAA_22 PF13401.1 EKG15684.1 - 0.084 13.0 1.0 0.52 10.4 0.7 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_S41 PF03572.13 EKG15685.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 AT_hook PF02178.14 EKG15686.1 - 0.043 13.4 12.3 0.29 10.9 0.6 3.6 3 0 0 3 3 3 0 AT hook motif XPG_I PF00867.13 EKG15687.1 - 3.5e-25 87.8 0.0 5.6e-24 84.0 0.0 2.9 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.12 EKG15687.1 - 6.4e-10 39.2 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EKG15687.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing Aldose_epim PF01263.15 EKG15688.1 - 1.7e-48 165.2 0.2 2.1e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase AMP-binding PF00501.23 EKG15692.1 - 1.7e-89 300.1 0.0 2.4e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG15692.1 - 1.3e-05 26.0 0.0 4.4e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_8 PF08022.7 EKG15692.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain ECH PF00378.15 EKG15693.1 - 1.3e-67 227.5 0.0 1.4e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EKG15693.1 - 0.026 14.6 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region DAO PF01266.19 EKG15694.1 - 9.4e-34 116.8 0.6 1.5e-33 116.1 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG15694.1 - 0.01 15.8 0.0 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG15694.1 - 0.027 14.2 0.2 0.42 10.3 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ferritin_2 PF13668.1 EKG15695.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain 2_5_RNA_ligase2 PF13563.1 EKG15696.1 - 1.5e-31 109.1 3.0 3.3e-31 108.0 2.1 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EKG15696.1 - 6.7e-21 74.2 0.0 1.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 EKG15696.1 - 1.9e-11 44.3 0.0 4.1e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 EKG15696.1 - 1.1e-09 38.2 0.4 2.4e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) PAP_RNA-bind PF04926.10 EKG15696.1 - 4.4e-06 26.3 0.0 1.3e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain PAP_assoc PF03828.14 EKG15696.1 - 0.0019 18.0 0.1 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Exo_endo_phos_2 PF14529.1 EKG15696.1 - 0.043 13.4 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase HVSL PF09749.4 EKG15696.1 - 0.061 12.3 0.5 0.12 11.3 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein Nrap PF03813.9 EKG15696.1 - 0.13 9.7 0.0 0.19 9.2 0.0 1.1 1 0 0 1 1 1 0 Nrap protein Pyr_redox PF00070.22 EKG15697.1 - 1.1e-06 28.9 0.0 2.7e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2817 PF10994.3 EKG15697.1 - 0.044 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Glyco_hyd_65N_2 PF14498.1 EKG15698.1 - 1.7e-33 116.2 0.0 4.9e-33 114.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF3129 PF11327.3 EKG15699.1 - 1.4e-59 200.9 12.1 1.4e-59 200.9 8.4 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3129) Ig_2 PF13895.1 EKG15699.1 - 0.078 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Peptidase_C13 PF01650.13 EKG15700.1 - 7.8e-42 143.3 0.1 1e-41 142.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family Aldolase_II PF00596.16 EKG15703.1 - 1.8e-47 161.3 0.0 2.2e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Homeobox_KN PF05920.6 EKG15704.1 - 5.8e-15 54.7 0.2 1.5e-14 53.3 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EKG15704.1 - 2.4e-07 30.2 0.3 5.7e-07 29.0 0.2 1.7 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_Tc5 PF03221.11 EKG15704.1 - 3.8e-07 29.8 0.0 1.3e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-C2H2 PF00096.21 EKG15704.1 - 0.00065 19.8 24.2 0.071 13.4 0.7 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG15704.1 - 0.02 15.2 1.1 0.02 15.2 0.8 6.2 7 0 0 7 7 7 0 C2H2-type zinc finger ECM11 PF15463.1 EKG15704.1 - 3.2 8.0 7.9 1.7 8.9 0.9 3.1 3 0 0 3 3 3 0 Extracellular mutant protein 11 5_nucleotid_C PF02872.13 EKG15705.1 - 1.8e-35 122.2 0.0 3.2e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EKG15705.1 - 1.6e-08 34.1 0.0 2.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG15705.1 - 8.5e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Thiolase_C PF02803.13 EKG15706.1 - 1.8e-38 130.7 0.4 2.5e-38 130.2 0.3 1.2 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 EKG15706.1 - 2.2e-37 128.4 0.3 3.2e-37 127.9 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Peptidase_S8 PF00082.17 EKG15707.1 - 9.7e-41 139.7 14.1 1.7e-40 138.9 9.8 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EKG15707.1 - 7.9e-05 23.1 0.2 0.00031 21.2 0.0 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 SH3_1 PF00018.23 EKG15709.1 - 2.1e-12 46.1 0.2 4.3e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG15709.1 - 3.2e-11 42.6 0.1 6.7e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKG15709.1 - 2.2e-05 23.8 0.0 4.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TPR_14 PF13428.1 EKG15709.1 - 6.1 7.7 6.6 3.9 8.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RPAP2_Rtr1 PF04181.8 EKG15710.1 - 1.4e-18 66.7 0.1 2.1e-18 66.1 0.1 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family Mit_ribos_Mrp51 PF11709.3 EKG15711.1 - 1e-38 133.3 0.0 1.3e-38 132.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit AAA_assoc_C PF09821.4 EKG15711.1 - 0.0027 17.9 0.7 0.0054 16.9 0.5 1.4 1 0 0 1 1 1 1 C-terminal AAA-associated domain Secretin PF00263.16 EKG15711.1 - 0.066 12.5 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 Bacterial type II and III secretion system protein Ribosomal_S17e PF00833.13 EKG15712.1 - 3.3e-59 197.9 0.5 4.1e-59 197.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EKG15712.1 - 0.016 15.8 0.2 0.024 15.3 0.2 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Csm1 PF12539.3 EKG15713.1 - 7.3e-27 93.6 0.0 1.9e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 APG6 PF04111.7 EKG15713.1 - 0.0018 17.4 8.0 0.0026 16.8 5.5 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF2353 PF09789.4 EKG15713.1 - 0.0025 17.1 4.7 0.0045 16.2 3.3 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) TSC22 PF01166.13 EKG15713.1 - 0.0048 16.8 0.7 0.014 15.3 0.5 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family AAA_13 PF13166.1 EKG15713.1 - 0.012 14.0 4.0 0.019 13.4 2.8 1.2 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 EKG15713.1 - 0.015 15.2 5.8 0.016 15.1 1.7 2.7 2 0 0 2 2 2 0 bZIP transcription factor TMF_DNA_bd PF12329.3 EKG15713.1 - 0.029 14.1 20.6 0.17 11.6 9.1 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 EKG15713.1 - 0.037 14.3 7.3 0.031 14.6 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Rootletin PF15035.1 EKG15713.1 - 0.13 12.1 7.4 0.25 11.2 5.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.4 EKG15713.1 - 0.13 12.0 9.0 0.047 13.5 4.1 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EKG15713.1 - 0.24 10.5 5.9 3.9 6.5 3.1 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 EKG15713.1 - 0.26 11.1 14.8 0.077 12.8 7.7 1.9 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EKG15713.1 - 0.41 9.8 11.0 1.1 8.3 7.7 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF904 PF06005.7 EKG15713.1 - 0.42 10.9 8.6 0.18 12.1 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Fzo_mitofusin PF04799.8 EKG15713.1 - 0.42 9.9 2.3 0.74 9.1 1.6 1.5 1 0 0 1 1 1 0 fzo-like conserved region V_ATPase_I PF01496.14 EKG15713.1 - 0.43 8.3 3.3 0.57 7.9 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EKG15713.1 - 0.47 10.1 4.7 0.4 10.3 0.3 2.4 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 IncA PF04156.9 EKG15713.1 - 0.95 9.0 10.5 3.7 7.0 7.2 2.0 1 1 0 1 1 1 0 IncA protein Lectin_N PF03954.9 EKG15713.1 - 1.1 8.7 5.6 3.4 7.0 2.9 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain SlyX PF04102.7 EKG15713.1 - 1.8 8.9 5.4 12 6.3 0.7 3.2 2 1 1 3 3 2 0 SlyX Cep57_CLD_2 PF14197.1 EKG15713.1 - 2.4 8.1 13.6 0.087 12.7 3.9 2.7 3 1 1 4 4 3 0 Centrosome localisation domain of PPC89 Kinetocho_Slk19 PF12709.2 EKG15713.1 - 4.5 7.4 11.3 0.49 10.4 1.1 2.8 2 1 1 3 3 2 0 Central kinetochore-associated ERM PF00769.14 EKG15713.1 - 5.2 6.5 18.6 0.029 13.8 6.3 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family adh_short PF00106.20 EKG15714.1 - 1.7e-20 73.6 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15714.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG15714.1 - 3.7e-07 30.1 0.0 4.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG15714.1 - 1.7e-05 24.3 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EKG15714.1 - 1.8e-05 25.0 0.2 4.6e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EKG15714.1 - 0.00019 21.5 0.0 0.0004 20.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EKG15714.1 - 0.00046 19.1 0.1 0.00065 18.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EKG15714.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EKG15714.1 - 0.003 16.5 0.1 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 EKG15714.1 - 0.023 14.2 0.1 0.085 12.4 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EKG15714.1 - 0.053 13.9 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 EKG15714.1 - 0.064 12.4 0.5 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family NAD_Gly3P_dh_N PF01210.18 EKG15714.1 - 0.082 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_4 PF07993.7 EKG15714.1 - 0.14 11.0 0.3 1.1 8.1 0.1 2.0 2 0 0 2 2 2 0 Male sterility protein Chitin_synth_1 PF01644.12 EKG15716.1 - 8.6e-85 282.5 0.1 1.2e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EKG15716.1 - 6.6e-32 109.0 0.1 1.3e-31 108.1 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EKG15716.1 - 2.9e-22 78.7 0.5 1.4e-18 66.5 0.0 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EKG15716.1 - 5.1e-09 36.1 0.7 5.1e-09 36.1 0.5 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG15716.1 - 0.00012 21.9 0.0 0.00036 20.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 NAD_binding_8 PF13450.1 EKG15718.1 - 1.4e-11 44.2 0.1 5e-11 42.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EKG15718.1 - 1.2e-06 27.8 0.1 2.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG15718.1 - 1.2e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EKG15718.1 - 1.8e-05 24.0 0.0 0.00022 20.4 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EKG15718.1 - 2.2e-05 23.5 0.3 4.6e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG15718.1 - 3e-05 22.6 0.1 4.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EKG15718.1 - 3.3e-05 22.9 0.2 6.5e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EKG15718.1 - 0.00065 20.0 0.1 0.0013 19.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG15718.1 - 0.0016 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG15718.1 - 0.005 15.7 0.1 0.029 13.2 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EKG15718.1 - 0.011 14.8 0.2 0.019 14.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EKG15718.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 EKG15718.1 - 0.095 12.0 0.1 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ApbA PF02558.11 EKG15718.1 - 0.096 12.1 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EKG15718.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EKG15718.1 - 0.11 12.0 0.1 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EKG15718.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EKG15718.1 - 0.13 10.8 0.1 0.19 10.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mpv17_PMP22 PF04117.7 EKG15719.1 - 2.4e-20 71.9 0.1 5.1e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family cobW PF02492.14 EKG15720.1 - 4.4e-44 150.0 0.1 5.9e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EKG15720.1 - 5.2e-05 22.8 0.1 0.00013 21.6 0.0 1.7 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 EKG15720.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase Septin PF00735.13 EKG15720.1 - 0.0019 17.2 0.2 0.29 10.0 0.0 2.1 2 0 0 2 2 2 1 Septin AAA_22 PF13401.1 EKG15720.1 - 0.0031 17.6 0.2 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKG15720.1 - 0.011 15.7 0.4 0.031 14.2 0.2 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EKG15720.1 - 0.011 15.4 0.0 0.039 13.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EKG15720.1 - 0.011 14.4 0.8 1.5 7.5 0.0 2.8 3 0 0 3 3 3 0 ArgK protein MobB PF03205.9 EKG15720.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EKG15720.1 - 0.024 14.9 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKG15720.1 - 0.047 13.1 0.1 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EKG15720.1 - 0.054 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EKG15720.1 - 0.057 12.6 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG15720.1 - 0.058 13.3 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EKG15720.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG15720.1 - 0.064 13.5 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_23 PF13476.1 EKG15720.1 - 0.1 12.9 0.1 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKG15720.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Fungal_trans PF04082.13 EKG15722.1 - 5.4e-65 218.8 0.1 7.7e-65 218.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EKG15722.1 - 1.8e-05 24.7 15.8 0.00021 21.4 1.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG15722.1 - 6.9e-05 22.9 14.0 0.0004 20.5 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG15722.1 - 0.01 16.1 8.9 0.2 12.0 1.9 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Na_Ca_ex PF01699.19 EKG15723.1 - 2.9e-27 94.9 12.9 2e-13 50.1 4.6 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein 7tm_7 PF08395.7 EKG15723.1 - 0.0026 16.8 0.1 0.2 10.6 0.0 2.3 1 1 0 2 2 2 1 7tm Chemosensory receptor DUF872 PF05915.7 EKG15723.1 - 0.019 14.8 0.6 0.083 12.7 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Anoctamin PF04547.7 EKG15723.1 - 0.36 9.4 2.2 1.1 7.8 0.1 2.2 1 1 0 2 2 2 0 Calcium-activated chloride channel zf-DHHC PF01529.15 EKG15723.1 - 0.36 10.1 2.8 0.66 9.3 0.0 2.3 2 1 0 2 2 2 0 DHHC palmitoyltransferase Adaptin_N PF01602.15 EKG15725.1 - 6.3e-135 450.4 11.9 7.9e-135 450.1 8.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EKG15725.1 - 3.2e-17 62.9 4.4 5.4e-17 62.1 0.2 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EKG15725.1 - 9.2e-16 57.9 3.0 2.1e-10 40.7 0.1 4.6 3 1 0 4 4 4 2 HEAT repeats HEAT PF02985.17 EKG15725.1 - 5.5e-12 44.6 0.6 0.0016 18.3 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EKG15725.1 - 2.4e-05 24.6 4.0 0.016 15.7 0.0 5.5 4 2 2 6 6 6 2 HEAT-like repeat CLASP_N PF12348.3 EKG15725.1 - 0.00014 21.2 1.0 1.1 8.5 0.0 3.7 2 1 1 3 3 3 2 CLASP N terminal Arm PF00514.18 EKG15725.1 - 0.00016 21.3 2.6 7.6 6.5 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EKG15725.1 - 0.0026 17.4 0.3 2.6 7.8 0.0 4.3 5 0 0 5 5 5 1 Spinocerebellar ataxia type 10 protein domain DUF2496 PF10689.4 EKG15725.1 - 0.022 14.3 0.7 0.1 12.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) DUF1077 PF06417.7 EKG15726.1 - 1.1e-49 166.9 0.2 1.4e-49 166.5 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF1441 PF07278.6 EKG15726.1 - 0.068 12.8 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1441) TMEM171 PF15471.1 EKG15726.1 - 0.54 8.9 3.6 0.82 8.3 2.5 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-AN1 PF01428.11 EKG15727.1 - 4.8e-12 45.5 9.6 7.8e-12 44.8 4.1 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger IBR PF01485.16 EKG15727.1 - 0.034 14.0 6.2 0.065 13.1 4.3 1.5 1 0 0 1 1 1 0 IBR domain FAD_binding_3 PF01494.14 EKG15728.1 - 1.5e-63 215.0 0.0 1.9e-63 214.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EKG15728.1 - 6.2e-60 201.6 0.0 1e-59 200.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain SE PF08491.5 EKG15728.1 - 0.092 11.5 0.0 1.6 7.5 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Cupin_8 PF13621.1 EKG15730.1 - 2.8e-34 118.7 0.0 4.2e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EKG15730.1 - 2.4e-07 30.2 0.0 9.8e-06 25.0 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_2 PF07883.6 EKG15730.1 - 0.013 14.9 0.0 0.041 13.3 0.0 1.9 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.17 EKG15730.1 - 0.014 15.6 0.0 0.073 13.3 0.0 2.1 2 0 0 2 2 2 0 JmjC domain, hydroxylase Aminotran_1_2 PF00155.16 EKG15732.1 - 8.6e-63 212.4 0.0 1e-62 212.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 EKG15732.1 - 0.036 12.7 0.0 0.058 12.0 0.0 1.3 1 0 0 1 1 1 0 Allinase BIR PF00653.16 EKG15733.1 - 6.2e-45 151.4 2.9 7.3e-22 77.5 0.4 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Mmp37 PF09139.6 EKG15734.1 - 6.9e-131 436.1 0.0 8.1e-131 435.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Glyco_hydro_47 PF01532.15 EKG15736.1 - 3.5e-116 388.5 0.0 4e-116 388.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TGT PF01702.13 EKG15737.1 - 2.6e-92 308.4 0.0 3.2e-92 308.1 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Hist_deacetyl PF00850.14 EKG15738.1 - 3.6e-63 213.7 0.0 5.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.6 EKG15738.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region DUF940 PF06082.6 EKG15738.1 - 1.2 7.6 6.6 1.9 6.9 4.6 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DUF1774 PF08611.5 EKG15739.1 - 2.5e-35 120.5 1.0 2.5e-35 120.5 0.7 2.3 4 1 0 4 4 4 1 Fungal protein of unknown function (DUF1774) FixQ PF05545.6 EKG15739.1 - 0.26 10.9 0.2 0.26 10.9 0.1 3.7 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_S58 PF03576.9 EKG15743.1 - 3.2e-108 361.7 1.4 3.7e-108 361.5 1.0 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fungal_trans PF04082.13 EKG15744.1 - 2.8e-28 98.5 0.0 4.5e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG15744.1 - 3.5e-09 36.4 11.6 5.9e-09 35.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EKG15745.1 - 7.8e-35 120.2 43.2 1.3e-32 112.9 16.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15745.1 - 3.5e-09 35.7 9.8 3.5e-09 35.7 6.8 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 EKG15745.1 - 0.00026 19.8 0.2 0.00043 19.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) BT1 PF03092.11 EKG15745.1 - 0.0089 14.7 1.0 0.038 12.7 0.8 1.8 1 1 0 1 1 1 1 BT1 family UQ_con PF00179.21 EKG15746.1 - 3.2e-07 29.8 0.4 6.4e-07 28.8 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EKG15746.1 - 0.012 15.5 0.1 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 RWD domain DUF1929 PF09118.6 EKG15747.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1929) Malate_synthase PF01274.17 EKG15747.1 - 0.14 10.1 0.0 0.17 9.8 0.0 1.0 1 0 0 1 1 1 0 Malate synthase zf-ribbon_3 PF13248.1 EKG15748.1 - 0.063 12.4 1.1 7.9 5.8 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EKG15748.1 - 0.066 12.5 1.7 6.9 6.0 0.0 2.7 3 0 0 3 3 3 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 EKG15748.1 - 5.7 6.8 7.4 20 5.0 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.4 EKG15748.1 - 7.7 6.3 7.7 1.9 8.2 0.8 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Nudix_N_2 PF14803.1 EKG15750.1 - 0.56 9.9 4.7 1.4 8.6 0.3 2.7 2 0 0 2 2 2 0 Nudix N-terminal Viral_P18 PF04521.8 EKG15750.1 - 0.74 9.2 5.0 0.1 12.0 0.3 1.9 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein FAM72 PF14976.1 EKG15750.1 - 4.9 6.9 8.3 0.61 9.9 0.7 2.3 1 1 0 2 2 2 0 FAM72 protein zf-ribbon_3 PF13248.1 EKG15750.1 - 7.6 5.8 7.7 5.9 6.2 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain INCENP_ARK-bind PF03941.10 EKG15752.1 - 1.5e-18 66.3 0.7 1.5e-18 66.3 0.5 3.0 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region DEAD PF00270.24 EKG15755.1 - 9.7e-40 135.8 0.0 1.5e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG15755.1 - 2.5e-22 78.5 0.1 6.9e-22 77.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG15755.1 - 3.5e-06 26.9 0.0 6.1e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EKG15755.1 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain UQ_con PF00179.21 EKG15757.1 - 2e-50 169.8 0.0 2.2e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG15757.1 - 6.3e-05 22.7 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKG15757.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.18 EKG15758.1 - 1.1e-112 376.0 0.2 2.9e-112 374.7 0.1 1.7 1 0 0 1 1 1 1 Kinesin motor domain ATG16 PF08614.6 EKG15758.1 - 0.0058 16.4 15.9 0.0058 16.4 11.0 5.0 3 1 1 5 5 5 2 Autophagy protein 16 (ATG16) DUF3349 PF11829.3 EKG15758.1 - 0.93 9.9 4.6 0.5 10.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) adh_short PF00106.20 EKG15760.1 - 3e-27 95.5 0.0 4.2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15760.1 - 1.1e-08 35.0 0.0 2.6e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG15760.1 - 2.4e-07 30.7 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG15760.1 - 0.027 13.9 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EKG15760.1 - 0.065 12.3 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Form_Nir_trans PF01226.12 EKG15761.1 - 1.1e-70 237.3 18.3 1.3e-70 237.2 12.7 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter RDD PF06271.7 EKG15761.1 - 7.4 6.4 16.2 16 5.3 0.9 2.7 1 1 1 2 2 2 0 RDD family GTP1_OBG PF01018.17 EKG15762.1 - 7.1e-38 129.7 0.6 1.9e-28 99.0 0.6 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EKG15762.1 - 5.4e-22 77.9 0.0 7.7e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG15762.1 - 1.4e-07 30.9 0.0 2.8e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 EKG15762.1 - 0.028 14.7 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 EKG15762.1 - 0.032 12.9 0.0 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EKG15762.1 - 0.061 13.1 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Miro PF08477.8 EKG15762.1 - 0.11 13.0 0.0 0.81 10.1 0.0 2.4 2 1 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EKG15762.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EKG15762.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EKG15762.1 - 0.22 10.7 0.0 0.6 9.3 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF2398 PF09661.5 EKG15765.1 - 0.0008 18.2 0.2 0.0011 17.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2398) Viral_Beta_CD PF04530.7 EKG15766.1 - 0.076 13.1 0.2 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Viral Beta C/D like family Methyltransf_8 PF05148.10 EKG15767.1 - 2.2e-55 187.6 0.1 3.8e-31 108.4 0.0 3.6 4 0 0 4 4 4 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EKG15767.1 - 3.9e-07 30.4 0.0 1.3e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15767.1 - 0.0053 16.3 0.1 3 7.3 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Peptidase_S49_N PF08496.5 EKG15767.1 - 0.12 12.2 0.1 0.12 12.2 0.1 4.3 3 1 2 5 5 5 0 Peptidase family S49 N-terminal Zip PF02535.17 EKG15767.1 - 3.4 6.5 7.7 68 2.3 5.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Asp_protease PF09668.5 EKG15768.1 - 1.5e-49 166.6 0.2 2.2e-49 166.1 0.2 1.2 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EKG15768.1 - 3.1e-12 46.8 0.0 1e-11 45.1 0.0 1.7 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.26 EKG15768.1 - 6.9e-10 38.4 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EKG15768.1 - 2.4e-07 30.4 0.0 6.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EKG15768.1 - 9e-07 28.8 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EKG15768.1 - 4.3e-05 23.3 0.0 0.00018 21.3 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EKG15768.1 - 0.0033 16.9 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain ubiquitin PF00240.18 EKG15769.1 - 1.1e-09 37.5 0.0 2.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKG15769.1 - 5.4e-06 25.9 0.2 1.7e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EKG15769.1 - 0.12 12.9 0.1 0.49 10.9 0.1 2.1 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Acetyltransf_1 PF00583.19 EKG15770.1 - 1.2e-12 47.6 0.0 1.8e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG15770.1 - 1.1e-08 35.1 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG15770.1 - 2e-05 24.4 0.0 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG15770.1 - 0.00029 20.5 0.0 0.00064 19.4 0.0 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EKG15770.1 - 0.00061 19.8 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG15770.1 - 0.0025 17.6 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EKG15770.1 - 0.022 14.6 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG15770.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fungal_trans PF04082.13 EKG15771.1 - 2.1e-33 115.3 0.0 4.6e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Golgin_A5 PF09787.4 EKG15772.1 - 0.5 8.8 3.5 0.57 8.6 2.4 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 LacAB_rpiB PF02502.13 EKG15773.1 - 4.1e-43 146.4 0.1 4.7e-43 146.1 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF3129 PF11327.3 EKG15774.1 - 1.1e-58 198.1 9.2 1.1e-58 198.1 6.4 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3129) Transp_cyt_pur PF02133.10 EKG15776.1 - 2e-85 286.9 35.8 2.3e-85 286.7 24.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Asp_Glu_race PF01177.17 EKG15777.1 - 3.5e-21 76.1 0.1 4e-21 75.9 0.1 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DHDPS PF00701.17 EKG15777.1 - 0.082 11.5 0.1 1.1 7.7 0.0 2.4 3 0 0 3 3 3 0 Dihydrodipicolinate synthetase family Ank_2 PF12796.2 EKG15778.1 - 6.3e-06 26.4 0.0 0.00093 19.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKG15778.1 - 0.00036 20.5 0.3 9 6.8 0.0 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EKG15778.1 - 0.012 15.3 0.0 13 5.7 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat adh_short PF00106.20 EKG15779.1 - 1.2e-23 83.9 1.7 1.9e-23 83.1 1.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG15779.1 - 5.2e-22 78.7 0.2 9e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG15779.1 - 1.6e-08 34.4 0.5 3.2e-08 33.4 0.4 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG15779.1 - 0.00037 19.9 0.1 0.00078 18.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 EKG15779.1 - 0.031 14.4 0.7 1.4 9.1 0.5 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix domain Mannitol_dh_C PF08125.8 EKG15780.1 - 9.7e-53 178.8 0.0 1.3e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EKG15780.1 - 1.8e-18 66.9 0.0 4.7e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EKG15780.1 - 0.0014 18.3 0.1 0.0039 16.8 0.0 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EKG15780.1 - 0.0047 16.3 0.4 0.025 13.9 0.1 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EKG15780.1 - 0.14 12.6 0.2 0.76 10.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Gti1_Pac2 PF09729.4 EKG15781.1 - 3.5e-59 199.4 0.0 5.1e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family MFS_1 PF07690.11 EKG15783.1 - 5.5e-30 104.2 39.7 5.5e-30 104.2 27.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.27 EKG15784.1 - 1.8e-23 81.4 14.4 1.3e-05 24.8 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Phospholip_B PF04916.8 EKG15784.1 - 0.0082 14.3 0.0 0.012 13.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase B MraZ PF02381.13 EKG15784.1 - 0.043 13.5 0.0 6.4 6.6 0.0 2.6 2 0 0 2 2 2 0 MraZ protein BBS2_N PF14781.1 EKG15784.1 - 0.11 12.0 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal PBP1_TM PF14812.1 EKG15784.1 - 0.42 10.9 9.4 1.4 9.2 6.5 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mg_trans_NIPA PF05653.9 EKG15785.1 - 4.1e-64 216.4 1.3 3.7e-59 200.1 0.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EKG15785.1 - 7.9e-05 22.8 0.1 7.9e-05 22.8 0.1 3.6 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EKG15785.1 - 0.005 16.8 3.6 0.005 16.8 2.5 4.4 3 2 1 4 4 4 2 EamA-like transporter family Daxx PF03344.10 EKG15785.1 - 0.68 8.3 10.0 1.5 7.1 0.9 2.1 2 0 0 2 2 2 0 Daxx Family DUF1772 PF08592.6 EKG15785.1 - 0.72 9.5 7.8 2.3 7.9 0.1 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) NAD_kinase PF01513.16 EKG15786.1 - 6.8e-46 156.3 0.0 3.2e-45 154.1 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EKG15787.1 - 2.4e-27 94.9 0.1 1.3e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase LysM PF01476.15 EKG15791.1 - 5.5e-11 42.1 3.1 0.00011 21.9 0.0 3.9 4 0 0 4 4 4 3 LysM domain Glyco_hydro_18 PF00704.23 EKG15792.1 - 6e-77 259.3 3.0 8.8e-77 258.8 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EKG15792.1 - 1.5e-07 31.2 15.6 1.5e-07 31.2 10.8 4.7 4 0 0 4 4 4 1 Chitin recognition protein GST_C PF00043.20 EKG15793.1 - 5.4e-10 39.1 0.0 2.5e-09 36.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG15793.1 - 1e-08 34.9 0.0 2.5e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG15793.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG15793.1 - 7.8e-06 26.2 0.0 1.5e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG15793.1 - 5.6e-05 23.0 0.0 0.00019 21.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG15793.1 - 0.00029 20.9 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2663 PF10864.3 EKG15794.1 - 1.1 9.4 4.8 0.23 11.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) DUF202 PF02656.10 EKG15794.1 - 5.3 7.3 6.3 41 4.4 4.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Fungal_trans_2 PF11951.3 EKG15796.1 - 1.3e-25 89.7 0.7 3.5e-25 88.4 0.5 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EKG15797.1 - 1.2e-64 218.5 0.0 1.4e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LTV PF04180.9 EKG15798.1 - 8.3e-63 213.3 13.0 1.5e-62 212.5 9.0 1.4 1 1 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.18 EKG15799.1 - 1.4e-17 63.7 0.1 1.9e-15 56.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG15799.1 - 7e-07 28.6 0.2 1.4e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EKG15799.1 - 0.0002 20.6 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EKG15799.1 - 0.00062 19.6 1.0 0.083 12.7 0.2 2.9 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EKG15799.1 - 0.0039 16.3 0.1 0.0074 15.4 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EKG15799.1 - 0.023 15.1 0.2 0.099 13.1 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Acyl-CoA_dh_1 PF00441.19 EKG15800.1 - 4e-28 98.4 0.1 6.1e-28 97.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG15800.1 - 4.3e-15 56.2 0.1 1.6e-14 54.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EKG15800.1 - 6.2e-15 54.4 0.0 1.5e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EKG15800.1 - 6e-13 49.2 0.2 9.7e-13 48.5 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2183 PF09949.4 EKG15800.1 - 0.093 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Glyco_transf_22 PF03901.12 EKG15801.1 - 2.4e-59 201.4 19.6 3.1e-59 201.0 13.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Skp1 PF01466.14 EKG15802.1 - 4.1e-39 132.4 1.9 4.1e-39 132.4 1.3 1.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EKG15802.1 - 1.8e-21 75.9 0.1 4.5e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EKG15802.1 - 0.02 14.8 1.0 0.028 14.3 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) PLDc_2 PF13091.1 EKG15803.1 - 4.1e-12 45.9 0.0 6.7e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EKG15803.1 - 7.4e-07 28.7 1.8 0.26 11.1 0.0 3.5 3 0 0 3 3 3 3 Phospholipase D Active site motif NDUFA12 PF05071.11 EKG15804.1 - 1.3e-26 93.0 3.7 1.9e-26 92.5 2.6 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ABC_tran PF00005.22 EKG15806.1 - 2.4e-53 180.0 0.0 1.2e-30 106.6 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EKG15806.1 - 1.7e-48 165.4 29.6 9.3e-28 97.4 5.5 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EKG15806.1 - 4e-09 36.8 0.0 0.0077 16.2 0.0 4.3 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EKG15806.1 - 1.8e-08 33.8 0.1 0.039 13.1 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EKG15806.1 - 1.1e-07 31.4 0.0 0.008 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKG15806.1 - 9.4e-07 28.9 0.0 0.0076 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EKG15806.1 - 3.1e-05 24.1 0.4 1.2 9.3 0.1 3.6 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EKG15806.1 - 6.8e-05 22.1 0.0 0.068 12.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EKG15806.1 - 0.00018 21.0 0.1 0.15 11.4 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain MMR_HSR1 PF01926.18 EKG15806.1 - 0.00019 21.3 0.1 0.17 11.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EKG15806.1 - 0.00021 21.6 0.1 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EKG15806.1 - 0.00029 21.2 1.8 0.42 11.1 0.0 3.1 3 1 0 3 3 2 2 Miro-like protein AAA PF00004.24 EKG15806.1 - 0.00046 20.3 0.2 0.4 10.8 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG15806.1 - 0.00073 20.3 0.1 3.7 8.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EKG15806.1 - 0.00073 18.5 0.0 0.31 9.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.18 EKG15806.1 - 0.0012 18.7 0.4 0.43 10.3 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.1 EKG15806.1 - 0.0014 18.1 0.1 1.6 8.3 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain MobB PF03205.9 EKG15806.1 - 0.004 16.8 0.8 2.2 7.9 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EKG15806.1 - 0.0065 15.5 0.3 3.9 6.5 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 EKG15806.1 - 0.0084 15.9 1.4 0.066 13.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 IstB_IS21 PF01695.12 EKG15806.1 - 0.0094 15.3 0.1 5.3 6.4 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 EKG15806.1 - 0.011 15.2 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EKG15806.1 - 0.015 15.6 0.0 7.7 6.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EKG15806.1 - 0.018 15.1 0.1 10 6.3 0.0 3.1 3 0 0 3 3 3 0 RNA helicase CbiA PF01656.18 EKG15806.1 - 0.019 14.3 2.4 0.022 14.1 0.1 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EKG15806.1 - 0.024 14.5 0.0 4.1 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EKG15806.1 - 0.028 14.1 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 EKG15806.1 - 0.033 13.9 0.4 2.5 7.8 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EKG15806.1 - 0.062 12.9 2.1 1.2 8.7 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.1 EKG15806.1 - 0.079 12.5 0.5 6.8 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EKG15806.1 - 0.083 12.3 0.4 2 7.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Adeno_IVa2 PF02456.10 EKG15806.1 - 0.17 10.4 0.0 0.4 9.2 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_5 PF07728.9 EKG15806.1 - 0.21 11.2 2.6 6.8 6.4 0.1 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.11 EKG15807.1 - 7.2e-43 146.6 27.8 1.1e-39 136.1 10.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EKG15807.1 - 0.00021 20.1 1.7 0.0005 18.8 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF791) OATP PF03137.15 EKG15807.1 - 0.00071 17.7 0.0 0.77 7.7 0.3 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EKG15807.1 - 0.00089 17.4 4.0 0.00089 17.4 2.8 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector Mem_trans PF03547.13 EKG15807.1 - 0.0065 14.8 0.0 0.013 13.8 0.0 1.4 1 0 0 1 1 1 1 Membrane transport protein Vpu PF00558.14 EKG15807.1 - 0.024 14.1 0.6 0.38 10.3 0.0 2.7 3 0 0 3 3 3 0 Vpu protein MFS_2 PF13347.1 EKG15807.1 - 2 6.6 18.6 0.078 11.3 4.2 3.2 3 0 0 3 3 3 0 MFS/sugar transport protein Fungal_trans PF04082.13 EKG15811.1 - 1.1e-12 47.4 0.1 2.2e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG15811.1 - 1.1e-07 31.6 8.8 2.4e-07 30.5 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C3HC4_3 PF13920.1 EKG15812.1 - 1.1e-05 25.0 8.7 0.00019 21.0 6.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG15812.1 - 5.1e-05 22.8 2.2 0.00067 19.2 1.8 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG15812.1 - 5.8e-05 22.8 9.2 0.00087 19.0 4.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EKG15812.1 - 0.00041 20.0 7.4 0.0022 17.6 5.1 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG15812.1 - 0.0006 19.7 8.5 0.00074 19.5 2.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG15812.1 - 0.068 13.2 1.8 0.14 12.2 1.3 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger Rtf2 PF04641.7 EKG15812.1 - 0.069 12.3 0.1 0.28 10.3 0.0 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger DNA_ligase_ZBD PF03119.11 EKG15812.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.6 2 1 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain UPF0547 PF10571.4 EKG15812.1 - 0.49 10.1 4.9 0.76 9.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.1 EKG15812.1 - 1.5 8.4 8.1 0.27 10.8 2.1 2.3 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EKG15812.1 - 2.7 7.9 8.8 21 5.0 0.2 3.0 2 1 1 3 3 3 0 IBR domain zf-C3HC4_4 PF15227.1 EKG15812.1 - 3 7.8 11.7 2.2 8.2 5.7 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EKG15812.1 - 3.2 7.5 7.7 0.9 9.3 0.9 2.4 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EKG15812.1 - 4.6 6.8 8.6 6.7 6.3 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EKG15812.1 - 8.6 6.1 8.2 22 4.8 2.8 2.5 2 1 0 2 2 2 0 RING-type zinc-finger Peptidase_A4 PF01828.12 EKG15813.1 - 8.2e-52 175.2 3.1 9.6e-52 175.0 2.1 1.0 1 0 0 1 1 1 1 Peptidase A4 family bZIP_2 PF07716.10 EKG15814.1 - 0.14 11.9 0.3 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper PT-VENN PF04829.8 EKG15814.1 - 2.7 7.6 9.0 0.97 9.0 2.8 2.1 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif AAA_14 PF13173.1 EKG15815.1 - 0.00087 19.1 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain STE PF02200.11 EKG15816.1 - 2e-61 204.9 0.3 3.7e-61 204.1 0.2 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EKG15816.1 - 6.7e-12 45.0 9.5 1.9e-06 27.8 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG15816.1 - 1.2e-09 37.8 9.6 0.0001 22.4 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG15816.1 - 1.5e-09 37.6 2.8 1.5e-09 37.6 1.9 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EKG15816.1 - 0.0002 21.1 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG15816.1 - 0.00049 20.1 0.3 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG15816.1 - 0.023 14.9 1.2 0.16 12.2 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EKG15816.1 - 0.03 14.4 2.6 0.053 13.6 1.8 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 EKG15816.1 - 0.053 14.1 0.2 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_3 PF14369.1 EKG15816.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 zinc-finger RAI1 PF08652.6 EKG15818.1 - 1.7e-12 46.9 0.1 3.7e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 EKG15820.1 - 2e-55 188.1 0.0 2.5e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Retrotrans_gag PF03732.12 EKG15822.1 - 1.4e-14 53.8 0.7 1.4e-14 53.8 0.5 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein DUF972 PF06156.8 EKG15822.1 - 0.0055 17.0 0.2 0.081 13.2 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF972) DivIC PF04977.10 EKG15822.1 - 0.094 12.2 1.7 0.23 10.9 0.8 1.9 2 0 0 2 2 2 0 Septum formation initiator Striatin PF08232.7 EKG15822.1 - 0.39 11.0 4.4 0.81 10.0 0.0 2.7 3 0 0 3 3 3 0 Striatin family IncA PF04156.9 EKG15822.1 - 1.3 8.5 3.6 2.4 7.7 0.8 2.1 2 0 0 2 2 2 0 IncA protein gag-asp_proteas PF13975.1 EKG15823.1 - 8.6e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EKG15823.1 - 9.5e-07 28.8 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EKG15823.1 - 3.4e-05 24.2 0.0 7.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease Claudin_2 PF13903.1 EKG15825.1 - 0.23 11.1 3.8 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fumarate_red_D PF02313.12 EKG15825.1 - 5.8 6.8 7.1 1.5 8.7 0.1 2.8 3 0 0 3 3 3 0 Fumarate reductase subunit D ADH_N PF08240.7 EKG15826.1 - 1.6e-24 85.7 0.1 2.6e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EKG15826.1 - 0.022 14.4 0.0 0.058 13.0 0.0 1.8 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated IGPD PF00475.13 EKG15827.1 - 1.1e-60 203.7 0.1 1.4e-60 203.3 0.1 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase RNA_pol_L_2 PF13656.1 EKG15828.1 - 7.7e-32 108.5 0.0 1e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EKG15828.1 - 3.3e-12 45.3 0.0 4.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR PF05347.10 EKG15829.1 - 3.1e-07 30.1 0.8 6.1e-07 29.1 0.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EKG15829.1 - 1.2e-05 25.3 0.5 1.8e-05 24.8 0.4 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EKG15829.1 - 8.1e-05 23.0 1.4 0.00011 22.6 0.9 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF651 PF04895.7 EKG15829.1 - 0.0079 15.8 0.4 0.0095 15.5 0.3 1.2 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF651) R-HINP1I PF11463.3 EKG15829.1 - 0.19 11.1 0.9 0.34 10.2 0.4 1.4 1 1 0 1 1 1 0 R.HinP1I restriction endonuclease G10 PF01125.12 EKG15830.1 - 1.3e-57 193.4 5.8 1.4e-57 193.3 4.0 1.0 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 EKG15831.1 - 1.4e-35 121.2 0.1 4.5e-35 119.5 0.1 1.9 1 0 0 1 1 1 1 Fork head domain ABC_tran PF00005.22 EKG15832.1 - 1.6e-46 158.0 0.0 8.2e-23 81.2 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EKG15832.1 - 2e-21 75.6 4.5 2e-21 75.6 3.1 2.9 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 EKG15832.1 - 2e-20 73.9 0.2 0.00012 22.2 0.0 4.3 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EKG15832.1 - 9.8e-11 41.0 0.1 0.00032 20.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EKG15832.1 - 6e-10 38.7 0.1 0.061 12.5 0.1 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKG15832.1 - 6.3e-10 39.7 10.5 0.00068 20.0 0.0 4.1 4 0 0 4 4 4 3 AAA domain DUF258 PF03193.11 EKG15832.1 - 4e-07 29.3 0.0 0.00057 19.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG15832.1 - 5.3e-06 27.2 0.1 0.042 14.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EKG15832.1 - 9.4e-06 26.1 0.1 0.033 14.6 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_18 PF13238.1 EKG15832.1 - 1e-05 25.8 0.1 0.065 13.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EKG15832.1 - 1.2e-05 25.5 0.0 0.066 13.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EKG15832.1 - 1.2e-05 25.3 0.0 0.0095 15.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG15832.1 - 1.7e-05 24.8 0.3 0.18 11.8 0.0 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EKG15832.1 - 2.1e-05 24.6 1.0 0.2 11.7 0.0 3.2 4 1 0 4 4 2 2 AAA domain NACHT PF05729.7 EKG15832.1 - 4.4e-05 23.2 0.2 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 EKG15832.1 - 4.5e-05 22.6 0.8 0.071 12.1 0.0 3.4 2 2 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.18 EKG15832.1 - 7.4e-05 22.6 0.2 0.47 10.4 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EKG15832.1 - 0.00012 21.5 0.0 0.84 8.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EKG15832.1 - 0.00023 21.3 0.0 0.99 9.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.9 EKG15832.1 - 0.00029 20.5 0.1 0.91 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EKG15832.1 - 0.0013 18.4 3.1 0.47 10.1 0.0 3.4 4 0 0 4 4 3 1 Archaeal ATPase AAA_14 PF13173.1 EKG15832.1 - 0.0019 18.0 0.0 3.6 7.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EKG15832.1 - 0.0021 17.5 0.0 1.8 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EKG15832.1 - 0.0024 17.7 3.0 1.7 8.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 EKG15832.1 - 0.0041 16.8 0.0 0.38 10.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 EKG15832.1 - 0.0099 14.8 0.1 2.4 6.9 0.0 2.8 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.17 EKG15832.1 - 0.012 14.5 0.0 3.2 6.5 0.0 3.1 3 1 0 3 3 3 0 NB-ARC domain SbcCD_C PF13558.1 EKG15832.1 - 0.016 15.1 0.7 0.78 9.7 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2813 PF11398.3 EKG15832.1 - 0.022 13.8 3.2 5.2 6.0 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2813) Ras PF00071.17 EKG15832.1 - 0.023 14.1 0.0 8.6 5.7 0.0 2.6 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.4 EKG15832.1 - 0.065 12.7 0.2 4.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EKG15832.1 - 0.093 12.4 0.1 14 5.3 0.1 2.6 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.18 EKG15832.1 - 0.11 12.2 5.6 5.6 6.7 0.0 3.8 4 1 1 5 5 3 0 Dynamin family ATP-synt_ab PF00006.20 EKG15832.1 - 0.13 11.7 0.0 2 7.8 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 EKG15832.1 - 3.8 5.8 14.7 6.4 5.0 0.0 4.3 4 1 0 4 4 4 0 AAA domain GIDA PF01134.17 EKG15834.1 - 5e-85 285.7 0.0 6.7e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EKG15834.1 - 3.6e-18 65.3 0.0 8.2e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 GidA associated domain 3 SNF2_N PF00176.18 EKG15835.1 - 2.6e-71 239.8 3.1 6.4e-71 238.5 2.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EKG15835.1 - 1.8e-52 177.0 22.5 1.8e-52 177.0 15.6 3.9 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 EKG15835.1 - 2.6e-16 59.2 0.0 5.8e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Brix PF04427.13 EKG15836.1 - 4.7e-39 134.0 0.2 6e-39 133.6 0.1 1.1 1 0 0 1 1 1 1 Brix domain DUF3067 PF11267.3 EKG15837.1 - 0.13 12.4 0.2 0.42 10.7 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3067) FTO_CTD PF12934.2 EKG15839.1 - 0.00055 19.5 0.0 0.00076 19.0 0.0 1.2 1 0 0 1 1 1 1 FTO C-terminal domain SSB PF00436.20 EKG15841.1 - 3.6e-16 58.8 0.0 4.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Tautomerase_2 PF14552.1 EKG15842.1 - 1.2e-27 95.7 0.0 2.1e-27 94.9 0.0 1.4 2 0 0 2 2 2 1 Tautomerase enzyme Tautomerase PF01361.16 EKG15842.1 - 1.3e-09 37.5 0.1 5.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme FAD_binding_3 PF01494.14 EKG15844.1 - 2.9e-17 62.7 0.0 4.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG15844.1 - 0.067 12.0 0.0 0.14 10.9 0.0 1.6 1 1 0 1 1 1 0 Squalene epoxidase Amino_oxidase PF01593.19 EKG15844.1 - 0.072 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase MFS_1 PF07690.11 EKG15845.1 - 4.9e-20 71.5 39.5 8.1e-19 67.5 27.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_N PF08240.7 EKG15847.1 - 0.00066 19.4 0.0 0.00081 19.1 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain polyprenyl_synt PF00348.12 EKG15848.1 - 1.1e-60 204.7 0.0 1.3e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EKG15849.1 - 9.2e-05 21.7 0.1 0.00083 18.6 0.0 2.1 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 EKG15850.1 - 3.2e-14 53.1 3.1 1.1e-12 48.1 2.2 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG15850.1 - 3.1e-06 26.9 0.5 7.8e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 KR domain Methyltransf_25 PF13649.1 EKG15850.1 - 0.0015 18.8 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.1 EKG15850.1 - 0.022 14.5 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EKG15850.1 - 0.031 14.0 1.1 0.068 12.9 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Toxin_13 PF07822.6 EKG15852.1 - 0.024 14.5 2.1 0.024 14.5 1.5 4.2 3 1 1 4 4 4 0 Neurotoxin B-IV-like protein AIRS_C PF02769.17 EKG15853.1 - 2.6e-33 115.2 0.0 5.1e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EKG15853.1 - 2.4e-17 62.9 1.6 5e-17 61.9 1.1 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain GHMP_kinases_C PF08544.8 EKG15853.1 - 0.00023 21.2 0.0 0.0018 18.4 0.0 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal GARS_A PF01071.14 EKG15854.1 - 3.1e-83 278.1 0.0 4.7e-83 277.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EKG15854.1 - 4.7e-35 120.0 0.0 1.3e-34 118.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.11 EKG15854.1 - 6.1e-28 96.8 0.1 1.6e-27 95.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EKG15854.1 - 8.1e-14 51.7 0.0 2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EKG15854.1 - 3.7e-07 29.6 0.0 6.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG15854.1 - 4e-06 25.8 0.0 1.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EKG15854.1 - 7.1e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EKG15854.1 - 3.8e-05 23.5 0.0 7.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EKG15854.1 - 0.00062 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.8 EKG15854.1 - 0.00071 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_2 PF08442.5 EKG15854.1 - 0.061 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain AgrB PF04647.10 EKG15855.1 - 0.037 13.0 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Accessory gene regulator B Colicin_V PF02674.11 EKG15855.1 - 0.054 13.3 0.3 0.071 12.9 0.2 1.2 1 0 0 1 1 1 0 Colicin V production protein Cation_efflux PF01545.16 EKG15855.1 - 0.078 12.0 0.0 0.085 11.9 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family DUF4064 PF13273.1 EKG15855.1 - 0.51 10.4 3.6 0.24 11.5 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2613 PF11021.3 EKG15855.1 - 4.8 6.9 8.3 0.77 9.5 3.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) Adap_comp_sub PF00928.16 EKG15856.1 - 3.7e-87 291.7 0.0 4.1e-87 291.6 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.4 EKG15856.1 - 0.0052 15.9 0.1 0.0078 15.4 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain CoA_binding PF02629.14 EKG15857.1 - 9.6e-28 96.5 2.7 9.1e-27 93.4 0.3 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EKG15857.1 - 1.1e-24 86.7 0.4 2.2e-24 85.8 0.3 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EKG15857.1 - 4.5e-09 36.0 0.1 8.1e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EKG15857.1 - 4e-05 23.7 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.17 EKG15857.1 - 0.017 15.6 0.1 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold IlvN PF07991.7 EKG15857.1 - 0.02 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Radical_SAM PF04055.16 EKG15858.1 - 1.1e-18 67.9 0.1 3.2e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EKG15858.1 - 6.1e-13 48.6 0.1 2e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG15858.1 - 0.006 16.7 0.0 0.019 15.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG15858.1 - 0.029 14.4 0.0 0.099 12.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 EKG15859.1 - 5.6e-28 97.1 1.9 9.8e-09 35.4 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EKG15859.1 - 1.1e-15 56.5 16.7 0.034 13.9 0.0 9.6 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EKG15859.1 - 2.1e-15 56.4 8.1 3.5e-05 23.9 0.0 5.8 7 0 0 7 7 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG15859.1 - 2.8e-13 49.9 4.1 0.0033 17.9 0.0 7.9 8 1 0 8 8 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG15859.1 - 3.9e-10 38.9 12.4 0.32 11.3 0.0 9.7 10 0 0 10 10 9 3 Ankyrin repeat AAA_16 PF13191.1 EKG15859.1 - 9.9e-10 38.7 0.0 1.6e-08 34.7 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EKG15859.1 - 1.4e-06 28.0 0.0 3.4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EKG15859.1 - 6.6e-05 23.0 0.0 0.00046 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EKG15859.1 - 0.0024 18.0 0.0 0.0086 16.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.9 EKG15859.1 - 0.01 15.1 0.1 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EKG15859.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EKG15859.1 - 0.012 15.8 0.0 0.059 13.5 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain AAA_19 PF13245.1 EKG15859.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EKG15859.1 - 0.14 11.8 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Abhydrolase_5 PF12695.2 EKG15859.1 - 0.17 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 EKG15859.1 - 0.35 10.5 0.0 0.72 9.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase PD40 PF07676.7 EKG15860.1 - 0.0045 16.6 0.5 0.026 14.1 0.1 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EKG15860.1 - 0.051 12.1 0.0 7.9 4.9 0.0 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_M14 PF00246.19 EKG15861.1 - 3.4e-13 49.8 0.1 6.8e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EKG15861.1 - 0.007 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) HET PF06985.6 EKG15862.1 - 1e-16 61.3 0.2 2.6e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_28 PF00295.12 EKG15865.1 - 2.4e-38 131.9 1.5 3.5e-38 131.3 1.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EKG15865.1 - 8.6e-05 22.3 16.4 0.0035 17.1 10.9 3.2 1 1 0 1 1 1 1 Right handed beta helix region PBD PF00786.23 EKG15866.1 - 0.033 14.6 0.1 0.033 14.6 0.1 2.9 4 0 0 4 4 4 0 P21-Rho-binding domain RRM_1 PF00076.17 EKG15869.1 - 2.7e-35 119.7 0.0 1.5e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG15869.1 - 5.7e-20 71.0 0.1 5.1e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG15869.1 - 2.8e-17 62.2 0.1 9.5e-09 34.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.5 EKG15869.1 - 0.0098 15.8 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.3 EKG15869.1 - 0.011 15.4 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 OB_RNB PF08206.6 EKG15869.1 - 0.042 13.3 0.1 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2015 PF09435.5 EKG15870.1 - 4e-48 162.4 0.0 4.4e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Caleosin PF05042.8 EKG15870.1 - 0.054 13.0 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Caleosin related protein PRT_C PF08372.5 EKG15870.1 - 0.06 12.8 0.1 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Ribosomal_L28e PF01778.12 EKG15871.1 - 3.1e-39 133.9 1.7 3.1e-39 133.9 1.1 1.4 2 0 0 2 2 2 1 Ribosomal L28e protein family DDE_1 PF03184.14 EKG15871.1 - 0.014 14.5 0.3 0.017 14.2 0.2 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease MFS_1 PF07690.11 EKG15872.1 - 7.6e-28 97.2 30.2 1.1e-27 96.7 20.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PMP1_2 PF08114.6 EKG15872.1 - 0.00051 19.4 0.8 0.19 11.2 0.0 3.4 2 0 0 2 2 2 2 ATPase proteolipid family Cyclin_N PF00134.18 EKG15873.1 - 3e-10 39.7 0.1 6.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RIX1 PF08167.7 EKG15874.1 - 1.9e-50 170.7 1.1 4.7e-50 169.4 0.7 1.7 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_1 PF00515.23 EKG15875.1 - 5.6e-11 41.5 0.5 0.02 14.5 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG15875.1 - 1.5e-10 40.5 3.6 6.7e-05 22.4 0.0 5.3 6 0 0 6 6 6 2 TPR repeat TPR_2 PF07719.12 EKG15875.1 - 8.5e-10 37.7 8.8 0.024 14.5 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG15875.1 - 2e-08 34.1 13.2 0.069 13.8 0.0 7.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG15875.1 - 0.00081 19.0 1.9 31 4.7 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKG15875.1 - 0.004 16.8 0.7 5.3 7.0 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG15875.1 - 0.0074 16.6 6.2 2.8 8.3 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG15875.1 - 0.011 16.4 15.4 1.9 9.2 0.2 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG15875.1 - 0.03 14.7 5.1 0.21 12.1 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKG15875.1 - 0.11 12.7 0.1 31 5.1 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat BAF1_ABF1 PF04684.8 EKG15875.1 - 0.57 8.9 7.6 0.98 8.1 5.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zn_clus PF00172.13 EKG15876.1 - 0.0059 16.4 5.7 0.18 11.7 0.7 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF508 PF04370.7 EKG15876.1 - 0.33 10.5 5.6 0.51 9.9 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Na_H_Exchanger PF00999.16 EKG15877.1 - 4.2e-62 209.8 30.6 4.9e-62 209.6 21.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MFS_2 PF13347.1 EKG15878.1 - 4.2e-08 32.0 9.2 4.2e-08 32.0 6.4 2.8 4 0 0 4 4 4 2 MFS/sugar transport protein P5-ATPase PF12409.3 EKG15879.1 - 7e-38 129.1 0.0 1.7e-37 127.9 0.0 1.7 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EKG15879.1 - 3.3e-29 102.4 0.0 6.9e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EKG15879.1 - 2.1e-28 98.9 0.0 4.5e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKG15879.1 - 2.1e-18 67.5 0.0 2.1e-17 64.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG15879.1 - 0.003 17.4 0.0 0.0068 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKG15879.1 - 0.011 15.3 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKG15879.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Ribosomal_S3Ae PF01015.13 EKG15880.1 - 1.1e-80 269.6 5.0 1.3e-80 269.3 3.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Erythro-docking PF09277.6 EKG15880.1 - 0.11 12.2 0.1 3.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Erythronolide synthase, docking DUF4588 PF15251.1 EKG15881.1 - 0.06 13.3 3.6 0.06 13.3 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Retinal PF15449.1 EKG15881.1 - 5.3 4.5 13.1 6.1 4.3 9.0 1.0 1 0 0 1 1 1 0 Retinal protein GTP_CH_N PF12471.3 EKG15882.1 - 2.6e-93 311.0 0.0 4e-93 310.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EKG15882.1 - 4.9e-17 61.6 0.0 8.2e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Elf1 PF05129.8 EKG15883.1 - 9.2e-29 98.9 2.4 1.1e-28 98.7 1.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 EKG15883.1 - 0.072 12.7 0.7 0.1 12.2 0.5 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Sec23_Sec24 PF04810.10 EKG15883.1 - 2.7 7.6 5.6 0.7 9.5 0.1 2.3 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger UPRTase PF14681.1 EKG15884.1 - 4.7e-82 274.2 0.0 6.5e-82 273.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EKG15884.1 - 0.00015 21.4 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EKG15884.1 - 0.12 12.1 0.2 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 EKG15885.1 - 9.1e-25 87.1 2.9 2.2e-24 85.8 2.0 1.6 1 1 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin RAP1 PF07218.6 EKG15885.1 - 9.3 4.2 6.6 14 3.5 2.9 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Ras PF00071.17 EKG15886.1 - 2.4e-45 153.8 0.3 2.7e-45 153.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG15886.1 - 1e-14 55.0 0.1 1.4e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG15886.1 - 2.9e-08 33.1 0.0 3.1e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG15886.1 - 3.6e-05 23.2 0.1 0.00072 19.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKG15886.1 - 4.1e-05 23.5 0.0 7.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKG15886.1 - 0.00015 21.0 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EKG15886.1 - 0.03 13.6 0.0 0.29 10.4 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_28 PF13521.1 EKG15886.1 - 0.037 13.9 0.1 0.29 11.0 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EKG15886.1 - 0.041 13.7 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 EKG15887.1 - 9.8e-30 104.1 0.0 1.3e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG15887.1 - 5.8e-19 68.5 0.0 2.8e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG15887.1 - 1.2e-12 47.8 0.0 2.8e-12 46.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EKG15887.1 - 5.4e-05 22.8 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EKG15887.1 - 0.0016 18.6 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EKG15887.1 - 0.025 14.0 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF915 PF06028.6 EKG15887.1 - 0.045 12.8 0.0 0.87 8.6 0.0 2.5 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Ndr PF03096.9 EKG15887.1 - 0.051 12.0 0.0 0.18 10.2 0.0 1.6 1 1 0 2 2 2 0 Ndr family DUF676 PF05057.9 EKG15887.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) G6PD_C PF02781.11 EKG15888.1 - 9e-136 451.4 0.0 1.4e-135 450.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EKG15888.1 - 1.3e-63 214.5 0.0 2.2e-63 213.8 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 EKG15888.1 - 0.0058 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) AAA_18 PF13238.1 EKG15889.1 - 3.2e-27 95.3 0.4 1.5e-26 93.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG15889.1 - 1.8e-11 44.8 3.3 1.3e-10 42.0 2.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EKG15889.1 - 0.00011 22.2 0.1 0.00057 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKG15889.1 - 0.00024 21.0 0.4 0.013 15.3 0.3 2.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG15889.1 - 0.00075 19.6 0.1 0.0017 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EKG15889.1 - 0.0023 18.1 0.0 0.0081 16.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.12 EKG15889.1 - 0.0029 17.0 0.1 2.1 7.6 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 EKG15889.1 - 0.0035 16.5 0.0 0.019 14.1 0.0 2.0 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_10 PF12846.2 EKG15889.1 - 0.0044 16.5 0.4 0.016 14.6 0.0 1.8 1 1 2 3 3 3 1 AAA-like domain NTPase_1 PF03266.10 EKG15889.1 - 0.0046 16.6 0.4 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.1 EKG15889.1 - 0.0056 16.6 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EKG15889.1 - 0.0057 16.5 0.0 0.027 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EKG15889.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SKI PF01202.17 EKG15889.1 - 0.031 14.1 0.0 5.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.12 EKG15889.1 - 0.055 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EKG15889.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EKG15889.1 - 0.077 12.7 0.2 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain ADK PF00406.17 EKG15889.1 - 0.078 12.8 0.2 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.16 EKG15889.1 - 0.083 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EKG15889.1 - 0.091 12.4 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EKG15889.1 - 0.098 12.3 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EKG15889.1 - 0.26 10.7 1.4 0.28 10.6 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ham1p_like PF01725.11 EKG15890.1 - 9.3e-53 178.4 0.0 1e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family p450 PF00067.17 EKG15891.1 - 5.9e-06 25.0 0.0 0.051 12.0 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 Myosin_head PF00063.16 EKG15892.1 - 1.4e-245 816.6 0.1 1.4e-245 816.6 0.0 1.4 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 EKG15892.1 - 8.1e-35 118.8 3.3 2.5e-34 117.3 2.3 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EKG15892.1 - 2.7e-14 51.3 33.7 7.3e-05 22.0 0.7 6.4 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_tail_1 PF01576.14 EKG15892.1 - 6.3e-05 20.9 26.1 0.00063 17.6 18.1 2.0 1 1 0 1 1 1 1 Myosin tail AAA_22 PF13401.1 EKG15892.1 - 0.00015 21.8 0.9 0.00048 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF812 PF05667.6 EKG15892.1 - 0.00019 20.1 14.8 0.00032 19.3 10.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.1 EKG15892.1 - 0.0019 17.4 9.0 0.0019 17.4 6.2 2.5 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_19 PF13245.1 EKG15892.1 - 0.0083 15.8 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EKG15892.1 - 0.013 15.4 0.4 0.2 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Fib_alpha PF08702.5 EKG15892.1 - 0.078 13.0 9.8 0.2 11.7 5.7 2.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 EKG15892.1 - 0.2 11.4 27.1 0.74 9.6 17.6 2.5 1 1 0 1 1 1 0 Tropomyosin like FUSC PF04632.7 EKG15892.1 - 0.26 9.6 8.3 0.47 8.8 5.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlaC_arch PF05377.6 EKG15892.1 - 0.53 10.2 6.6 0.24 11.3 0.1 3.3 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EKG15892.1 - 0.96 9.0 26.4 8.9 5.8 18.3 2.4 1 1 0 1 1 1 0 IncA protein DUF972 PF06156.8 EKG15892.1 - 1.3 9.3 18.9 2.3 8.6 5.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 EKG15892.1 - 2 7.4 27.0 0.78 8.7 14.4 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 Surfac_D-trimer PF09006.6 EKG15892.1 - 2.7 7.8 5.6 2.4 7.9 0.3 2.8 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation CENP-F_leu_zip PF10473.4 EKG15892.1 - 2.8 7.8 26.4 2.3 8.0 2.8 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.7 EKG15892.1 - 8.2 6.1 17.4 3.7 7.3 3.8 2.5 1 1 0 2 2 2 0 Laminin Domain II Peptidase_C78 PF07910.8 EKG15893.1 - 3.4e-59 199.6 0.0 4.9e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EKG15893.1 - 0.0053 16.8 2.5 0.014 15.5 0.1 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L35Ae PF01247.13 EKG15894.1 - 5.9e-44 147.7 0.3 6.6e-44 147.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EKG15894.1 - 0.0012 18.7 0.0 0.59 10.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain 2-Hacid_dh_C PF02826.14 EKG15895.1 - 7.9e-53 178.2 0.0 1.2e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG15895.1 - 1.7e-35 121.3 0.0 2.3e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EKG15895.1 - 7.3e-06 25.9 0.4 1.6e-05 24.8 0.3 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EKG15895.1 - 0.00094 19.0 0.1 0.0025 17.6 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EKG15895.1 - 0.0019 17.6 0.0 0.0051 16.2 0.0 1.8 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 EKG15895.1 - 0.0022 17.4 0.2 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EKG15895.1 - 0.012 15.2 0.3 0.98 9.0 0.5 2.4 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CECR6_TMEM121 PF14997.1 EKG15895.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 CECR6/TMEM121 family NAP PF00956.13 EKG15896.1 - 3e-84 281.9 11.9 3.5e-84 281.7 8.2 1.0 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Striatin PF08232.7 EKG15896.1 - 0.27 11.5 5.9 0.25 11.6 2.0 2.1 2 0 0 2 2 2 0 Striatin family MFS_2 PF13347.1 EKG15897.1 - 1.5e-17 63.1 10.8 1.5e-17 63.1 7.5 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein DUF1228 PF06779.9 EKG15897.1 - 0.1 12.6 8.2 0.91 9.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MFS_1_like PF12832.2 EKG15897.1 - 0.8 9.5 0.0 0.8 9.5 0.0 3.9 3 1 1 4 4 4 0 MFS_1 like family GIY-YIG PF01541.19 EKG15898.1 - 1.6e-06 28.4 0.3 2.3e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain tRNA-synt_1b PF00579.20 EKG15900.1 - 4.1e-74 249.3 0.0 5.1e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF883 PF05957.8 EKG15900.1 - 0.41 11.0 3.1 1.1 9.7 2.2 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) BAR PF03114.13 EKG15901.1 - 3.6e-59 200.0 1.5 4.6e-59 199.7 1.1 1.1 1 0 0 1 1 1 1 BAR domain Sigma70_ner PF04546.8 EKG15901.1 - 0.021 14.4 0.6 0.064 12.8 0.1 2.1 2 1 0 2 2 2 0 Sigma-70, non-essential region Arfaptin PF06456.8 EKG15901.1 - 0.022 14.0 5.2 0.53 9.5 3.6 2.2 1 1 0 1 1 1 0 Arfaptin-like domain DUF2884 PF11101.3 EKG15901.1 - 0.4 10.0 3.5 1.4 8.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Peptidase_S10 PF00450.17 EKG15902.1 - 6e-63 213.4 0.0 7.1e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase ADH_zinc_N PF00107.21 EKG15904.1 - 9.3e-20 70.5 0.0 1.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG15904.1 - 6.6e-07 30.2 0.0 1e-06 29.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EKG15904.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EKG15904.1 - 0.0042 16.2 0.7 0.0066 15.6 0.5 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG15904.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Brix PF04427.13 EKG15905.1 - 4.3e-37 127.6 0.1 7.1e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 EKG15905.1 - 0.00039 18.5 20.2 0.00051 18.1 14.0 1.1 1 0 0 1 1 1 1 Nop14-like family Mem_trans PF03547.13 EKG15905.1 - 0.2 9.9 0.1 0.22 9.7 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Sporozoite_P67 PF05642.6 EKG15905.1 - 0.25 9.1 8.9 0.34 8.7 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 EKG15905.1 - 1.6 7.1 19.3 2.2 6.6 13.4 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 EKG15905.1 - 4.1 5.5 15.5 5.3 5.1 10.8 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Astro_capsid PF03115.9 EKG15905.1 - 4.4 5.4 7.3 6.7 4.8 5.1 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor NOA36 PF06524.7 EKG15905.1 - 5.7 6.0 9.0 8.3 5.5 6.2 1.3 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 EKG15905.1 - 7.5 5.4 12.6 13 4.6 8.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit S-antigen PF05756.6 EKG15905.1 - 8.7 6.3 9.4 20 5.2 6.5 1.7 1 0 0 1 1 1 0 S-antigen protein tRNA-synt_2b PF00587.20 EKG15906.1 - 1.1e-67 226.9 0.0 1.6e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKG15906.1 - 9.1e-20 70.4 0.5 4.8e-19 68.0 0.0 2.5 2 1 0 2 2 2 1 Anticodon binding domain VSP PF03302.8 EKG15908.1 - 0.00053 18.7 4.7 0.00053 18.7 3.2 1.7 2 0 0 2 2 2 1 Giardia variant-specific surface protein DUF2668 PF10873.3 EKG15908.1 - 0.0016 18.6 1.8 0.0017 18.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) Amnionless PF14828.1 EKG15908.1 - 0.0045 15.5 0.0 0.0068 14.9 0.0 1.2 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.5 EKG15908.1 - 0.0057 15.9 0.4 0.013 14.8 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PepSY_TM_2 PF13703.1 EKG15908.1 - 0.045 13.9 0.3 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix DUF1049 PF06305.6 EKG15908.1 - 0.17 11.3 0.4 0.35 10.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) TrbC PF04956.8 EKG15908.1 - 8.8 6.4 12.5 0.14 12.2 0.6 2.3 2 0 0 2 2 2 0 TrbC/VIRB2 family REV PF00424.13 EKG15909.1 - 0.17 11.8 1.9 0.37 10.7 0.8 1.8 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Cation_efflux PF01545.16 EKG15910.1 - 6.2e-38 130.5 11.0 7.9e-38 130.1 7.7 1.1 1 0 0 1 1 1 1 Cation efflux family SecY PF00344.15 EKG15911.1 - 6.1e-97 324.6 11.2 8.2e-97 324.2 7.7 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EKG15911.1 - 2.5e-18 65.2 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Sec8_exocyst PF04048.9 EKG15912.1 - 1.3e-46 157.7 4.2 3.4e-46 156.3 2.9 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EKG15912.1 - 3.5e-11 42.5 4.2 5e-11 42.0 1.5 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EKG15912.1 - 5.8e-06 24.7 2.9 1e-05 23.9 2.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.1 EKG15912.1 - 0.00024 20.8 0.4 0.00063 19.5 0.3 1.7 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 EKG15912.1 - 0.0025 17.6 1.1 0.0025 17.6 0.8 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 PIG-P PF08510.7 EKG15913.1 - 3.3e-42 143.0 0.0 5.1e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 PIG-P Mito_carr PF00153.22 EKG15917.1 - 8.1e-66 217.7 0.1 1.6e-20 72.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.7 EKG15918.1 - 7.9e-17 60.7 1.2 1e-16 60.4 0.9 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.15 EKG15919.1 - 1.3e-58 198.3 0.0 1.8e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Cu_amine_oxid PF01179.15 EKG15920.1 - 5.2e-174 578.8 0.0 6.2e-174 578.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EKG15920.1 - 4.4e-19 68.4 0.1 1.1e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EKG15920.1 - 2e-12 46.9 0.1 3.8e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain HeLo PF14479.1 EKG15921.1 - 0.07 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Prion-inhibition and propagation MBOAT_2 PF13813.1 EKG15922.1 - 1.2e-17 63.6 2.6 1.2e-17 63.6 1.8 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family TGS PF02824.16 EKG15923.1 - 1.1e-22 79.5 0.3 2.1e-22 78.6 0.2 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EKG15923.1 - 3e-20 72.3 0.2 1.6e-19 69.9 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG15923.1 - 5.1e-13 48.5 0.0 8.6e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EKG15923.1 - 2.2e-05 24.3 0.2 0.028 14.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EKG15923.1 - 0.0016 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EKG15923.1 - 0.023 13.8 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 EKG15923.1 - 0.046 12.4 0.1 0.11 11.2 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 EKG15923.1 - 0.095 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family AAA_17 PF13207.1 EKG15923.1 - 0.27 12.0 1.4 1.5 9.6 0.9 2.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKG15923.1 - 0.28 11.4 1.6 1.8 8.8 1.1 2.2 1 1 0 1 1 1 0 AAA domain CLTH PF10607.4 EKG15924.1 - 4e-32 110.9 0.0 7.1e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EKG15924.1 - 7.9e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 LisH DUF3446 PF11928.3 EKG15924.1 - 0.33 11.1 6.6 0.045 13.9 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF2431 PF10354.4 EKG15925.1 - 3.1e-49 167.1 0.0 2.6e-48 164.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Mucin PF01456.12 EKG15925.1 - 3 7.6 16.3 5.6 6.7 11.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein BRE1 PF08647.6 EKG15926.1 - 5.1e-24 84.0 11.7 5.1e-24 84.0 8.1 6.4 4 1 1 5 5 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 EKG15926.1 - 3.3e-08 33.0 3.0 6.9e-08 32.0 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG15926.1 - 3.8e-08 33.2 4.9 6.9e-08 32.3 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG15926.1 - 1.6e-07 30.8 4.4 1.6e-07 30.8 3.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG15926.1 - 6.8e-07 28.9 3.7 1.2e-06 28.0 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKG15926.1 - 4.5e-06 26.3 3.3 1.1e-05 25.1 2.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EKG15926.1 - 1.9e-05 24.2 5.0 4.6e-05 23.0 3.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger DUF1192 PF06698.6 EKG15926.1 - 0.00011 21.9 2.2 0.00011 21.9 1.5 6.9 8 1 1 9 9 8 2 Protein of unknown function (DUF1192) HALZ PF02183.13 EKG15926.1 - 0.00024 20.7 0.5 0.00024 20.7 0.3 7.6 7 2 0 7 7 6 1 Homeobox associated leucine zipper zf-C3HC4_4 PF15227.1 EKG15926.1 - 0.00061 19.6 2.9 0.0011 18.7 2.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ATG16 PF08614.6 EKG15926.1 - 0.001 18.9 16.6 0.001 18.9 11.5 5.7 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EKG15926.1 - 0.0012 18.7 14.6 0.0012 18.7 10.1 6.5 3 1 5 8 8 7 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 EKG15926.1 - 0.0025 17.8 3.2 0.0025 17.8 2.2 6.0 2 1 2 4 4 3 2 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.3 EKG15926.1 - 0.012 15.3 65.1 0.076 12.7 1.7 8.3 3 1 5 8 8 8 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EKG15926.1 - 0.11 11.7 27.9 0.045 12.9 4.2 4.9 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Rad50_zn_hook PF04423.9 EKG15926.1 - 0.17 11.3 5.4 14 5.2 0.0 5.2 4 0 0 4 4 4 0 Rad50 zinc hook motif Prok-RING_4 PF14447.1 EKG15926.1 - 0.49 9.9 5.1 2.2 7.8 3.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EKG15926.1 - 0.58 9.7 6.2 5.1 6.7 4.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PaaB PF06243.6 EKG15926.1 - 0.59 10.2 9.6 0.18 11.9 1.5 2.9 2 0 0 2 2 2 0 Phenylacetic acid degradation B Myb_DNA-binding PF00249.26 EKG15927.1 - 3.5e-06 26.9 0.0 7.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Response_reg PF00072.19 EKG15928.1 - 2.2e-21 75.9 0.1 5.7e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EKG15928.1 - 1.5e-19 69.7 0.0 2.6e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EKG15928.1 - 4.3e-14 52.7 0.0 9e-12 45.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain HisKA PF00512.20 EKG15928.1 - 3.6e-10 39.7 0.1 3.6e-10 39.7 0.0 2.6 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EKG15928.1 - 2.3e-06 27.6 0.1 0.0012 18.8 0.0 3.6 2 1 0 2 2 2 1 PAS fold PAS PF00989.19 EKG15928.1 - 0.00029 20.5 0.0 0.13 12.0 0.0 3.5 2 1 0 2 2 2 1 PAS fold PAS_8 PF13188.1 EKG15928.1 - 0.00086 19.0 0.0 0.031 14.1 0.0 2.7 2 0 0 2 2 2 1 PAS domain GAF_2 PF13185.1 EKG15928.1 - 0.002 18.6 0.0 0.0068 16.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EKG15928.1 - 0.092 12.8 0.0 0.28 11.2 0.0 2.0 1 0 0 1 1 1 0 GAF domain Collagen PF01391.13 EKG15929.1 - 6.9 6.3 71.0 0.14 11.7 11.1 4.8 1 1 2 3 3 3 0 Collagen triple helix repeat (20 copies) Aconitase PF00330.15 EKG15934.1 - 1.8e-23 82.7 0.1 3.1e-23 82.0 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EKG15934.1 - 4.7e-20 72.0 0.0 8.1e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF3292 PF11696.3 EKG15936.1 - 5.5e-10 37.7 0.7 3.1e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) Reticulon PF02453.12 EKG15936.1 - 0.54 9.8 4.5 0.42 10.2 0.2 2.1 1 1 0 2 2 2 0 Reticulon MFS_1 PF07690.11 EKG15937.1 - 5.2e-07 28.7 70.2 2.6e-05 23.1 44.9 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG15937.1 - 1.5e-05 23.4 17.6 1.5e-05 23.4 12.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG15939.1 - 8.5e-27 93.7 42.4 1.4e-19 70.0 13.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2029 PF09594.5 EKG15939.1 - 0.0049 16.3 4.3 0.0049 16.3 3.0 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF2029) Con-6 PF10346.4 EKG15940.1 - 5e-20 70.6 2.1 8.3e-13 47.5 0.7 2.3 2 0 0 2 2 2 2 Conidiation protein 6 FKBP_N PF01346.13 EKG15940.1 - 0.029 14.4 1.2 0.48 10.4 0.2 2.1 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Phage_attach PF05354.6 EKG15940.1 - 0.049 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Phage Head-Tail Attachment NUMOD3 PF07460.6 EKG15940.1 - 0.14 12.0 0.4 0.44 10.4 0.2 2.0 1 1 1 2 2 2 0 NUMOD3 motif (2 copies) 4HBT PF03061.17 EKG15941.1 - 2.8e-11 43.3 0.0 4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EKG15941.1 - 1.1e-06 28.6 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.11 EKG15942.1 - 1.5e-39 135.7 28.8 1.6e-37 129.0 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG15942.1 - 4.6e-09 35.3 2.8 4.6e-09 35.3 1.9 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EKG15942.1 - 2.9e-06 25.9 14.9 0.0004 18.9 4.6 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EKG15942.1 - 0.0058 16.3 3.9 0.38 10.5 0.0 3.0 2 1 0 2 2 2 1 MFS_1 like family DUF4626 PF15422.1 EKG15942.1 - 0.0067 16.3 0.0 0.034 14.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4626) LacY_symp PF01306.14 EKG15942.1 - 0.0077 14.8 4.4 0.017 13.7 3.0 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter MRP-S33 PF08293.6 EKG15943.1 - 2.1e-29 101.2 0.0 2.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.21 EKG15944.1 - 7.2e-17 61.8 0.1 2.3e-16 60.2 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EKG15944.1 - 9.1e-14 51.5 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EKG15944.1 - 0.00016 22.1 0.1 0.00034 21.1 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Rubis-subs-bind PF09273.6 EKG15944.1 - 0.1 12.5 1.7 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding MoCF_biosynth PF00994.19 EKG15945.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain Orthopox_A47 PF06334.6 EKG15945.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus A47 protein AA_kinase PF00696.23 EKG15946.1 - 3e-38 131.7 0.0 4.1e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EKG15946.1 - 4.4e-12 45.2 1.3 8.2e-09 34.7 0.1 2.9 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 EKG15946.1 - 2.3e-11 43.0 2.5 1.7e-08 33.8 0.1 2.8 3 0 0 3 3 3 2 ACT domain Pkinase PF00069.20 EKG15948.1 - 2.9e-59 200.3 0.0 3.4e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG15948.1 - 1.5e-30 106.1 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG15948.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 EKG15948.1 - 0.057 12.4 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CMAS PF02353.15 EKG15949.1 - 5.2e-37 127.4 0.4 7.3e-37 126.9 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EKG15949.1 - 4.4e-14 52.7 0.0 7.2e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG15949.1 - 7.8e-14 51.5 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG15949.1 - 9.8e-13 48.1 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG15949.1 - 1.8e-11 44.6 0.0 2.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG15949.1 - 8e-09 35.8 0.0 1.4e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG15949.1 - 1.4e-07 31.0 0.0 2.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EKG15949.1 - 2.2e-06 27.9 0.0 3.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG15949.1 - 0.00016 20.7 0.0 0.00046 19.3 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EKG15949.1 - 0.00047 19.7 0.0 0.0015 18.1 0.0 1.8 2 1 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EKG15949.1 - 0.0007 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.9 EKG15949.1 - 0.001 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EKG15949.1 - 0.0017 17.5 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.10 EKG15949.1 - 0.035 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RrnaAD PF00398.15 EKG15949.1 - 0.047 12.7 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase B_lectin PF01453.19 EKG15950.1 - 1.5e-06 28.0 3.1 1.5e-06 28.0 2.1 2.9 1 1 0 1 1 1 1 D-mannose binding lectin Trep_Strep PF09605.5 EKG15950.1 - 0.0017 18.0 0.1 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Shisa PF13908.1 EKG15950.1 - 0.0071 16.5 0.9 0.011 15.8 0.6 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3862 PF12978.2 EKG15950.1 - 0.027 14.1 0.9 0.057 13.0 0.1 1.9 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3862) Med3 PF11593.3 EKG15950.1 - 0.03 13.5 11.2 0.038 13.2 7.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal P12 PF12669.2 EKG15950.1 - 0.13 12.5 1.2 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family CRA PF06589.6 EKG15950.1 - 0.22 10.7 1.8 0.36 10.1 0.9 1.6 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Cna_B PF05738.8 EKG15950.1 - 0.53 10.0 3.3 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Cna protein B-type domain Rifin_STEVOR PF02009.11 EKG15950.1 - 1.4 8.5 0.0 1.4 8.5 0.0 2.2 2 1 0 2 2 2 0 Rifin/stevor family Macoilin PF09726.4 EKG15950.1 - 2.6 6.1 5.4 3.1 5.9 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Init_tRNA_PT PF04179.7 EKG15951.1 - 9.8e-149 496.0 0.0 1.2e-148 495.7 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase E1-E2_ATPase PF00122.15 EKG15952.1 - 3e-61 206.3 8.8 7.1e-61 205.1 6.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG15952.1 - 5e-33 114.1 2.3 5e-33 114.1 1.6 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG15952.1 - 2.6e-27 96.6 0.0 3.9e-26 92.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKG15952.1 - 1.6e-16 59.4 0.1 1.6e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EKG15952.1 - 1.1e-14 54.1 0.0 2.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EKG15952.1 - 3.6e-12 46.8 0.1 1.3e-11 45.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG15952.1 - 2.9e-06 27.0 3.6 6.3e-05 22.6 0.8 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase SIR2_2 PF13289.1 EKG15952.1 - 0.31 10.9 0.0 0.59 10.0 0.0 1.3 1 0 0 1 1 1 0 SIR2-like domain Abhydrolase_3 PF07859.8 EKG15953.1 - 6.6e-17 61.7 0.0 8.2e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EKG15953.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Pkinase PF00069.20 EKG15954.1 - 6.7e-44 149.9 0.0 1.1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG15954.1 - 9e-29 100.3 0.0 1.2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKG15954.1 - 1.1e-06 27.8 0.0 3.1e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG15954.1 - 0.0014 18.4 0.2 0.0096 15.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKG15954.1 - 0.0022 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EKG15954.1 - 0.0031 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EKG15954.1 - 0.0039 16.1 0.1 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like P21-Arc PF04062.9 EKG15955.1 - 6.9e-79 263.6 0.0 7.8e-79 263.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Rad17 PF03215.10 EKG15956.1 - 0.026 13.2 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EKG15957.1 - 1.1e-14 54.1 0.0 2.2e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.8 EKG15957.1 - 0.00076 19.0 0.0 0.0025 17.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit TIP49 PF06068.8 EKG15957.1 - 0.023 13.3 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Rad17 PF03215.10 EKG15957.1 - 0.036 12.7 0.0 0.063 11.9 0.0 1.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 EKG15957.1 - 0.041 13.5 0.1 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA PF00004.24 EKG15957.1 - 0.15 12.2 0.1 1.2 9.3 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF3816 PF12822.2 EKG15960.1 - 0.025 14.4 0.1 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF89 PF01937.14 EKG15961.1 - 1.9e-99 332.8 0.0 2.2e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Phi-29_GP4 PF05464.6 EKG15961.1 - 0.096 12.5 0.0 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 Phi-29-like late genes activator (early protein GP4) Melibiase PF02065.13 EKG15963.1 - 0.0005 18.8 0.0 0.00079 18.2 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_97 PF10566.4 EKG15963.1 - 0.0011 18.1 0.0 0.0095 15.0 0.0 2.0 1 1 0 1 1 1 1 Glycoside hydrolase 97 Mrr_cat PF04471.7 EKG15963.1 - 0.17 11.7 0.0 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Restriction endonuclease APH PF01636.18 EKG15965.1 - 1.1e-11 44.9 4.5 8.2e-11 42.0 3.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKG15965.1 - 3.3e-05 23.5 0.0 4.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Striatin PF08232.7 EKG15966.1 - 1.2e-39 135.6 8.5 1.2e-39 135.6 5.9 1.7 2 0 0 2 2 2 1 Striatin family WD40 PF00400.27 EKG15966.1 - 3.3e-35 118.7 14.0 7.4e-10 38.3 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EKG15966.1 - 0.058 13.1 0.1 18 4.9 0.0 3.1 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term TBPIP PF07106.8 EKG15966.1 - 0.17 11.4 3.9 0.3 10.6 2.7 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) eIF2A PF08662.6 EKG15966.1 - 0.26 10.9 0.0 0.56 9.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Mei4 PF13971.1 EKG15966.1 - 1.4 7.7 5.6 2.3 7.0 3.9 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Glyco_hydro_76 PF03663.9 EKG15968.1 - 5.1e-96 322.2 14.1 3.6e-95 319.4 9.4 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 HSF_DNA-bind PF00447.12 EKG15969.1 - 2.2e-28 98.4 0.8 2.2e-28 98.4 0.6 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Peptidase_M13 PF01431.16 EKG15969.1 - 0.018 14.1 0.7 0.04 13.0 0.5 1.5 1 0 0 1 1 1 0 Peptidase family M13 YlbD_coat PF14071.1 EKG15969.1 - 0.043 13.8 6.6 0.14 12.2 4.6 1.9 1 0 0 1 1 1 0 Putative coat protein Amino_oxidase PF01593.19 EKG15969.1 - 0.2 10.7 1.9 0.55 9.2 0.3 2.0 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Herpes_LMP1 PF05297.6 EKG15969.1 - 2.4 7.0 10.0 6.6 5.5 7.0 1.7 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Abhydrolase_6 PF12697.2 EKG15970.1 - 5.4e-17 62.4 0.1 6.7e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG15970.1 - 1.2e-08 34.7 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family SKG6 PF08693.5 EKG15971.1 - 7e-05 22.0 0.1 0.00013 21.1 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EKG15971.1 - 0.00047 19.6 0.4 0.00085 18.7 0.3 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF2029 PF09594.5 EKG15971.1 - 0.025 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF4514 PF14986.1 EKG15971.1 - 0.058 13.2 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) eRF1_2 PF03464.10 EKG15972.1 - 3.5e-47 160.0 0.1 5.9e-47 159.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 PDT PF00800.13 EKG15972.1 - 2.2e-41 141.4 0.2 5.1e-23 81.5 0.1 2.4 1 1 1 2 2 2 2 Prephenate dehydratase eRF1_3 PF03465.10 EKG15972.1 - 1.7e-38 131.3 0.2 4.3e-38 130.0 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EKG15972.1 - 1.8e-28 98.7 0.0 7e-28 96.8 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 1 ACT PF01842.20 EKG15972.1 - 0.0014 18.0 0.0 0.0047 16.3 0.0 1.9 1 0 0 1 1 1 1 ACT domain Aa_trans PF01490.13 EKG15973.1 - 7.1e-62 209.1 27.5 8.3e-62 208.9 19.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3321 PF11968.3 EKG15974.1 - 1e-54 185.4 0.0 1.4e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EKG15974.1 - 0.0096 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_L23 PF00276.15 EKG15975.1 - 5.1e-14 51.9 0.8 8.7e-14 51.2 0.5 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 SRPRB PF09439.5 EKG15975.1 - 0.02 14.1 0.1 0.022 13.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-Tim10_DDP PF02953.10 EKG15976.1 - 3.4e-22 77.5 0.9 4.4e-22 77.1 0.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2054 PF10218.4 EKG15976.1 - 0.044 13.6 0.3 0.055 13.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) ADH_zinc_N PF00107.21 EKG15978.1 - 4.1e-28 97.5 0.1 6.4e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG15978.1 - 6.5e-27 93.4 0.1 9.9e-27 92.8 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EKG15978.1 - 1.8e-06 28.8 0.0 3.9e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EKG15978.1 - 0.0019 18.2 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EKG15978.1 - 0.0032 16.5 0.1 0.0041 16.1 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 EKG15978.1 - 0.014 15.6 0.1 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EKG15978.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3A PF00803.13 EKG15978.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 3A/RNA2 movement protein family ADH_N_assoc PF13823.1 EKG15978.1 - 0.025 14.2 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated NAD_binding_3 PF03447.11 EKG15978.1 - 0.084 13.2 0.2 0.22 11.8 0.1 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EKG15978.1 - 0.091 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OPT PF03169.10 EKG15979.1 - 6.8e-119 398.0 26.0 8.1e-119 397.8 18.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 EKG15979.1 - 0.22 10.5 0.2 0.58 9.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4131 PF13567.1 EKG15979.1 - 5.7 6.3 14.2 0.3 10.4 2.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.19 EKG15980.1 - 5.9e-108 361.3 21.1 6.8e-108 361.1 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG15980.1 - 2.1e-27 95.7 23.0 6.8e-19 67.7 3.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG15980.1 - 0.0046 15.2 2.1 0.0089 14.2 1.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EKG15980.1 - 0.17 9.9 8.1 0.062 11.3 2.1 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peroxin-3 PF04882.7 EKG15981.1 - 3.4e-149 497.2 0.1 4e-149 497.0 0.1 1.0 1 0 0 1 1 1 1 Peroxin-3 PA PF02225.17 EKG15981.1 - 0.096 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 PA domain DUF1649 PF07855.7 EKG15982.1 - 1.7e-60 203.4 0.0 1.9e-60 203.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Mo-co_dimer PF03404.11 EKG15982.1 - 0.047 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Shisa PF13908.1 EKG15983.1 - 2e-05 24.8 0.1 2.1e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM51 PF15345.1 EKG15983.1 - 0.0059 16.3 0.0 0.0059 16.3 0.0 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 SCIMP PF15050.1 EKG15983.1 - 0.021 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 SCIMP protein IncA PF04156.9 EKG15983.1 - 0.024 14.2 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 EKG15983.1 - 0.045 12.0 0.0 0.045 12.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2422 PF10337.4 EKG15983.1 - 0.065 12.0 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF2668 PF10873.3 EKG15983.1 - 0.068 13.3 4.4 0.082 13.0 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2668) G0-G1_switch_2 PF15103.1 EKG15983.1 - 0.097 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 Ctr PF04145.10 EKG15983.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF4448 PF14610.1 EKG15983.1 - 0.14 11.6 0.4 0.21 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2749 PF10907.3 EKG15983.1 - 0.16 11.8 0.6 0.26 11.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) HemY_N PF07219.8 EKG15983.1 - 0.25 10.9 1.3 0.36 10.4 0.9 1.4 1 1 0 1 1 1 0 HemY protein N-terminus DUF3481 PF11980.3 EKG15983.1 - 0.31 10.8 2.0 0.3 10.9 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) EphA2_TM PF14575.1 EKG15983.1 - 0.36 11.2 3.4 0.71 10.3 2.4 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.6 EKG15983.1 - 0.47 9.5 3.9 0.15 11.1 0.2 1.8 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) RCR PF12273.3 EKG15983.1 - 1.5 9.3 5.6 3.5 8.1 3.8 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MttA_Hcf106 PF02416.11 EKG15983.1 - 2.3 7.4 4.8 4.1 6.5 3.3 1.4 1 0 0 1 1 1 0 mttA/Hcf106 family TMEM154 PF15102.1 EKG15984.1 - 0.015 15.0 0.0 0.5 10.0 0.0 2.4 2 0 0 2 2 2 0 TMEM154 protein family TCR_zetazeta PF11628.3 EKG15984.1 - 0.092 12.2 0.3 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain DUF4234 PF14018.1 EKG15984.1 - 0.11 12.3 3.6 6.8 6.5 0.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) SOR_SNZ PF01680.12 EKG15985.1 - 1.1e-80 270.0 1.6 1.1e-80 270.0 1.1 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EKG15985.1 - 5.4e-08 32.2 2.6 1.3e-06 27.6 0.1 2.6 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG Dus PF01207.12 EKG15985.1 - 0.0018 17.1 0.3 0.12 11.1 0.0 2.4 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EKG15985.1 - 0.0027 17.0 0.2 0.051 12.8 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 EKG15985.1 - 0.0073 15.4 2.9 0.015 14.4 2.0 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IGPS PF00218.16 EKG15985.1 - 0.0083 15.2 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EKG15985.1 - 0.0092 14.9 0.3 0.096 11.6 0.0 2.3 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 EKG15985.1 - 0.017 13.9 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase PcrB PF01884.12 EKG15985.1 - 0.026 13.7 0.2 0.046 12.9 0.1 1.4 1 1 0 1 1 1 0 PcrB family Trp_syntA PF00290.15 EKG15985.1 - 0.049 12.1 0.0 0.078 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain OMPdecase PF00215.19 EKG15985.1 - 0.054 12.8 0.8 0.29 10.5 0.6 1.9 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family FUN14 PF04930.10 EKG15986.1 - 0.00011 22.3 1.0 0.00029 21.0 0.7 1.8 1 1 0 1 1 1 1 FUN14 family DUF3487 PF11990.3 EKG15986.1 - 0.044 13.1 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) ABC1 PF03109.11 EKG15988.1 - 2.2e-35 121.2 0.0 5.7e-35 119.8 0.0 1.8 1 0 0 1 1 1 1 ABC1 family DUF3235 PF11574.3 EKG15988.1 - 0.1 12.8 4.1 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) CN_hydrolase PF00795.17 EKG15989.1 - 5.2e-14 52.0 0.0 7.4e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase IBN_N PF03810.14 EKG15990.1 - 2.4e-05 24.1 1.6 4.7e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain SICA_beta PF12878.2 EKG15990.1 - 0.14 11.9 0.5 2.8 7.7 0.2 2.4 1 1 1 2 2 2 0 SICA extracellular beta domain Peptidase_M24 PF00557.19 EKG15991.1 - 5.2e-43 147.0 0.0 7.4e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EKG15991.1 - 3e-21 76.2 0.0 5.7e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ORC2 PF04084.9 EKG15992.1 - 1.8e-99 332.6 0.0 2.8e-99 332.0 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ArgJ PF01960.13 EKG15993.1 - 3.2e-147 489.9 1.8 3.6e-147 489.8 1.3 1.0 1 0 0 1 1 1 1 ArgJ family ARD PF03079.9 EKG15994.1 - 9.6e-39 132.8 0.1 2.6e-35 121.7 0.0 2.1 2 0 0 2 2 2 2 ARD/ARD' family Cupin_2 PF07883.6 EKG15994.1 - 9.3e-09 34.6 0.1 1.7e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EKG15994.1 - 2.3e-05 24.1 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EKG15994.1 - 0.0017 17.7 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Cupin DUF896 PF05979.7 EKG15994.1 - 0.12 11.9 0.1 0.33 10.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) Sec15 PF04091.7 EKG15995.1 - 6.1e-109 364.1 1.7 6.1e-109 364.1 1.2 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Seryl_tRNA_N PF02403.17 EKG15995.1 - 0.57 10.2 5.4 17 5.4 0.5 3.6 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.6 EKG15995.1 - 1.1 9.1 9.1 0.26 11.1 1.9 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 EKG15995.1 - 8.6 5.9 9.7 0.38 10.3 0.7 3.1 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain RRM_2 PF04059.7 EKG15997.1 - 9.9e-20 70.3 0.0 1.3e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EKG15997.1 - 0.014 14.9 0.0 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2890 PF11081.3 EKG15998.1 - 0.028 14.4 4.3 0.031 14.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF4544 PF15077.1 EKG15998.1 - 0.25 10.8 2.9 0.32 10.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) RR_TM4-6 PF06459.7 EKG15998.1 - 4.6 7.0 10.5 5 6.9 7.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3106 PF11304.3 EKG16000.1 - 1.2 9.6 4.9 1.7 9.1 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) Pkinase PF00069.20 EKG16001.1 - 1.5e-69 234.0 0.0 2.9e-69 233.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG16001.1 - 3.4e-53 180.3 0.7 4.3e-53 180.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EKG16001.1 - 6.5e-22 77.7 0.0 2e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.1 EKG16001.1 - 2.7e-08 34.0 0.0 6.5e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 EKG16001.1 - 1.6e-07 30.6 0.0 2.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EKG16001.1 - 0.016 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EKG16001.1 - 0.019 14.6 0.2 0.019 14.6 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family CH PF00307.26 EKG16002.1 - 4.2e-37 126.4 0.5 2.9e-19 69.0 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EKG16002.1 - 8.9e-26 89.6 1.3 3.1e-25 87.9 0.1 2.6 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EKG16002.1 - 2.5e-10 39.8 0.2 1.4e-06 27.8 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.1 EKG16002.1 - 1.2e-05 24.7 0.2 0.0017 18.0 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 EKG16002.1 - 5.6e-05 22.1 0.1 0.016 14.4 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EKG16002.1 - 8.3e-05 22.1 0.4 0.0055 16.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 EKG16002.1 - 0.00094 19.2 3.4 0.002 18.2 0.7 2.9 3 0 0 3 3 3 1 EF-hand domain pair Spectrin PF00435.16 EKG16002.1 - 0.1 12.8 5.4 2.3 8.5 0.2 3.2 3 0 0 3 3 3 0 Spectrin repeat FUSC PF04632.7 EKG16002.1 - 0.32 9.3 1.1 0.44 8.9 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FliG_N PF14842.1 EKG16002.1 - 3.4 7.8 6.2 0.7 10.0 0.1 2.8 3 1 0 4 4 4 0 FliG N-terminal domain Na_H_Exchanger PF00999.16 EKG16003.1 - 5.2e-06 25.2 9.1 0.00027 19.6 0.3 3.2 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family DUF3816 PF12822.2 EKG16003.1 - 0.00048 20.0 4.7 0.18 11.6 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3816) MFS_1_like PF12832.2 EKG16003.1 - 0.079 12.7 1.3 0.23 11.2 0.0 2.4 2 1 0 2 2 2 0 MFS_1 like family Pam17 PF08566.5 EKG16003.1 - 0.081 12.6 0.0 2.3 7.8 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 DUF1754 PF08555.5 EKG16003.1 - 6.1 7.5 15.3 0.47 11.0 1.2 2.5 3 0 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Pox_A12 PF04651.8 EKG16004.1 - 0.27 11.3 1.0 0.45 10.6 0.7 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein OmpH PF03938.9 EKG16004.1 - 1.5 8.6 7.3 7 6.5 5.1 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 EKG16004.1 - 7.2 4.8 6.2 20 3.4 4.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Macro PF01661.16 EKG16005.1 - 1.1e-29 102.7 0.0 2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Macro domain HSF_DNA-bind PF00447.12 EKG16005.1 - 7.1e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding FHA PF00498.21 EKG16005.1 - 0.0021 18.1 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Phosphodiest PF01663.17 EKG16006.1 - 2.4e-16 60.0 0.8 2.4e-16 60.0 0.5 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EKG16006.1 - 8.8e-06 25.1 0.0 4.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Sulfatase PigN PF04987.9 EKG16006.1 - 0.0021 16.8 0.9 0.0021 16.8 0.6 2.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Metalloenzyme PF01676.13 EKG16006.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Glyco_hydro_71 PF03659.9 EKG16007.1 - 1e-57 195.3 0.0 1.3e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_98M PF08306.6 EKG16007.1 - 0.094 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 UCH_1 PF13423.1 EKG16008.1 - 2.1e-68 230.9 0.0 7.6e-68 229.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.16 EKG16009.1 - 6.1e-14 51.5 0.0 6.3e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EKG16009.1 - 4e-06 26.5 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 SNF2_N PF00176.18 EKG16010.1 - 7.1e-63 212.1 0.0 1.2e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG16010.1 - 1e-12 47.7 0.0 3.8e-12 45.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EKG16010.1 - 1.4e-05 24.6 10.9 1.4e-05 24.6 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 EKG16010.1 - 0.00012 21.0 0.0 0.00026 19.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.1 EKG16010.1 - 0.0018 18.0 11.0 0.0018 18.0 7.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EKG16010.1 - 0.012 15.3 11.4 0.012 15.3 7.9 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EKG16010.1 - 0.13 12.0 3.7 0.46 10.2 2.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EKG16010.1 - 4 7.5 22.6 0.022 14.7 7.2 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RGS PF00615.14 EKG16011.1 - 2.3e-05 24.4 0.0 0.0035 17.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Sugar_tr PF00083.19 EKG16012.1 - 7.6e-27 93.9 6.6 9.4e-27 93.6 4.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 EKG16013.1 - 4.1e-10 38.9 3.2 6.1e-10 38.4 2.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_33 PF10017.4 EKG16013.1 - 0.041 13.7 0.7 0.11 12.3 0.5 1.7 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Pyr_redox_3 PF13738.1 EKG16014.1 - 9.8e-21 74.7 0.2 4.1e-20 72.7 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG16014.1 - 2.7e-18 65.4 0.0 1.6e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EKG16014.1 - 1.1e-09 38.4 0.0 2.5e-05 24.2 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG16014.1 - 4.9e-09 35.5 0.0 3.7e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EKG16014.1 - 0.0011 18.9 0.1 0.056 13.4 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG16014.1 - 0.0019 17.9 0.0 0.76 9.5 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EKG16014.1 - 0.0028 18.0 3.0 0.023 15.0 0.0 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG16014.1 - 0.022 14.8 0.0 0.54 10.3 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EKG16014.1 - 0.034 13.4 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EKG16014.1 - 0.05 12.7 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EKG16014.1 - 0.068 12.2 0.6 2 7.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain ELFV_dehydrog PF00208.16 EKG16014.1 - 0.087 12.3 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Lycopene_cycl PF05834.7 EKG16014.1 - 0.69 8.7 2.4 47 2.7 0.0 3.3 4 0 0 4 4 4 0 Lycopene cyclase protein F-box-like_2 PF13013.1 EKG16016.1 - 0.051 13.2 0.0 0.088 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain DinB_2 PF12867.2 EKG16018.1 - 0.045 14.0 1.6 0.16 12.3 1.1 2.0 1 1 0 1 1 1 0 DinB superfamily MFS_1 PF07690.11 EKG16020.1 - 1.8e-38 132.1 32.6 2.5e-38 131.6 22.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HupE_UreJ_2 PF13795.1 EKG16020.1 - 0.0075 15.7 0.1 0.025 14.0 0.1 1.9 1 0 0 1 1 1 1 HupE / UreJ protein DUF485 PF04341.7 EKG16020.1 - 0.083 12.6 0.0 0.083 12.6 0.0 2.6 3 1 1 4 4 4 0 Protein of unknown function, DUF485 Cellulase PF00150.13 EKG16021.1 - 0.0055 15.9 0.0 0.0063 15.7 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ADH_N PF08240.7 EKG16023.1 - 2e-10 40.4 0.2 6.6e-10 38.7 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG16023.1 - 9.8e-10 38.0 1.2 1.2e-09 37.8 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EKG16024.1 - 0.0059 15.5 0.1 0.009 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EKG16026.1 - 9.2e-84 279.8 57.5 2.2e-44 151.1 12.1 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EKG16026.1 - 2.2e-39 134.8 0.0 3.6e-20 72.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG16026.1 - 4.2e-35 119.5 1.3 4.5e-29 100.1 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EKG16026.1 - 1.7e-17 63.2 0.0 4.2e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EKG16026.1 - 3e-09 36.3 10.3 3e-09 36.3 7.1 2.9 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EKG16026.1 - 6.4e-08 32.2 0.0 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EKG16026.1 - 3.2e-07 29.6 0.2 0.0004 19.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG16026.1 - 1.4e-05 25.1 2.1 0.00029 20.8 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EKG16026.1 - 0.00037 19.9 0.9 0.012 15.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EKG16026.1 - 0.00049 19.5 1.3 0.042 13.2 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKG16026.1 - 0.00069 19.7 0.2 0.4 10.8 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EKG16026.1 - 0.00091 19.5 0.0 0.082 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG16026.1 - 0.0012 19.6 0.0 0.18 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKG16026.1 - 0.0023 17.7 0.1 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EKG16026.1 - 0.003 17.2 0.9 0.52 9.9 0.2 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 EKG16026.1 - 0.0041 17.1 0.1 1.2 8.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 EKG16026.1 - 0.012 16.1 0.1 7.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EKG16026.1 - 0.017 15.1 0.4 6.1 6.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EKG16026.1 - 0.029 14.1 1.4 2.5 7.9 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 EKG16026.1 - 0.03 13.5 0.0 1 8.5 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 EKG16026.1 - 0.035 14.3 0.2 1.9 8.7 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EKG16026.1 - 0.078 12.4 1.4 7.1 5.9 0.0 2.7 2 1 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EKG16026.1 - 0.11 12.6 0.1 7.7 6.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 EKG16026.1 - 0.11 12.0 1.0 0.35 10.4 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EKG16026.1 - 0.18 11.7 3.6 0.076 12.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EKG16026.1 - 0.25 10.4 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin PDR_assoc PF08370.6 EKG16026.1 - 0.42 10.1 6.4 1.3 8.5 0.2 3.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated DUF1593 PF07632.6 EKG16027.1 - 5.5e-79 265.1 0.0 7.1e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EKG16027.1 - 0.0035 15.7 0.0 0.0056 15.0 0.0 1.2 1 0 0 1 1 1 1 REJ domain p450 PF00067.17 EKG16029.1 - 2.5e-31 108.7 0.0 3e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ORF6C PF10552.4 EKG16029.1 - 0.0052 16.5 0.2 0.0098 15.6 0.2 1.5 1 0 0 1 1 1 1 ORF6C domain MBOAT_2 PF13813.1 EKG16030.1 - 2e-19 69.4 2.9 3.7e-19 68.5 2.0 1.4 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family YfcL PF08891.6 EKG16031.1 - 0.1 12.6 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 YfcL protein polyprenyl_synt PF00348.12 EKG16032.1 - 8.1e-43 146.1 0.0 1.3e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EKG16032.1 - 1.3e-08 34.4 0.0 0.00018 20.8 0.0 2.3 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Med11 PF10280.4 EKG16032.1 - 0.043 13.8 0.1 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Mediator complex protein p450 PF00067.17 EKG16033.1 - 1.3e-58 198.6 0.0 1.7e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cutinase PF01083.17 EKG16034.1 - 2.2e-47 161.0 6.2 2.7e-47 160.8 4.3 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 EKG16034.1 - 0.0016 18.3 0.1 0.0018 18.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EKG16034.1 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EKG16034.1 - 0.0025 17.5 0.5 0.0031 17.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EKG16034.1 - 0.0055 16.1 0.3 0.008 15.6 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.15 EKG16034.1 - 0.0055 16.9 0.1 0.0073 16.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF1749 PF08538.5 EKG16034.1 - 0.0063 15.4 0.0 0.0073 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 EKG16034.1 - 0.036 13.6 0.1 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Autoind_bind PF03472.10 EKG16035.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain MFS_1 PF07690.11 EKG16036.1 - 1.5e-39 135.6 23.4 1.5e-39 135.6 16.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EKG16038.1 - 1.6e-69 234.6 0.0 2e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like_2 PF13013.1 EKG16039.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain Adeno_E3B PF03376.9 EKG16040.1 - 5.5 6.9 7.5 0.89 9.5 1.4 2.3 2 0 0 2 2 2 0 Adenovirus E3B protein Epimerase PF01370.16 EKG16041.1 - 0.00029 20.3 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG16041.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding AMP-binding PF00501.23 EKG16042.1 - 2.2e-07 29.6 0.0 2.5e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 EKG16043.1 - 1.6e-23 82.8 0.1 3.1e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EKG16044.1 - 2.4e-28 99.5 0.1 2.9e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG16044.1 - 1.9e-11 43.9 0.2 1.1e-10 41.4 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG16044.1 - 4.2e-10 39.5 0.3 4.4e-07 29.6 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 EKG16044.1 - 0.0047 16.5 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 EKG16044.1 - 0.0049 16.1 0.0 0.0076 15.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ndr PF03096.9 EKG16044.1 - 0.077 11.4 0.0 0.17 10.3 0.0 1.5 1 1 0 1 1 1 0 Ndr family DUF3431 PF11913.3 EKG16044.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) Aldedh PF00171.17 EKG16045.1 - 8.8e-154 512.2 0.0 9.9e-154 512.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EKG16045.1 - 0.052 12.7 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) FAD_binding_3 PF01494.14 EKG16046.1 - 4.8e-19 68.6 0.0 1.2e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG16046.1 - 6.5e-09 35.1 5.0 0.0011 18.0 2.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG16046.1 - 2.4e-05 24.2 2.1 5.1e-05 23.2 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG16046.1 - 2.7e-05 23.2 2.7 2.7e-05 23.2 1.9 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG16046.1 - 6.7e-05 22.8 0.0 0.0013 18.6 0.4 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG16046.1 - 0.00016 20.7 1.0 0.001 18.0 0.7 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EKG16046.1 - 0.00023 19.9 2.6 0.032 12.8 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EKG16046.1 - 0.00059 20.1 1.2 0.019 15.3 0.6 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG16046.1 - 0.0043 15.5 3.5 0.011 14.2 1.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EKG16046.1 - 0.0043 16.1 0.3 0.0056 15.7 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG16046.1 - 0.0072 16.4 0.6 0.026 14.5 0.6 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EKG16046.1 - 0.0075 15.9 0.6 0.011 15.3 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EKG16046.1 - 0.0098 14.7 0.7 0.018 13.8 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EKG16046.1 - 0.023 13.7 1.1 0.041 12.9 0.8 1.3 1 0 0 1 1 1 0 Thi4 family Acyl-CoA_dh_1 PF00441.19 EKG16047.1 - 2.4e-18 66.6 0.1 3e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EKG16047.1 - 0.089 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG16048.1 - 6.6e-07 29.8 0.6 1.6e-06 28.7 0.4 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Pectate_lyase PF03211.8 EKG16050.1 - 2.9e-69 232.7 8.6 3.8e-69 232.3 5.9 1.0 1 0 0 1 1 1 1 Pectate lyase FAD_binding_3 PF01494.14 EKG16051.1 - 1.4e-14 53.9 0.8 3.2e-10 39.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG16051.1 - 2.6e-07 30.5 0.3 5.5e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG16051.1 - 3.2e-07 29.6 4.2 7.5e-07 28.3 2.0 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG16051.1 - 2.9e-05 24.0 0.1 6.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG16051.1 - 6.8e-05 21.9 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EKG16051.1 - 7.6e-05 21.9 0.0 0.00011 21.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG16051.1 - 9.5e-05 22.7 0.6 0.00024 21.4 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG16051.1 - 0.0012 17.7 3.4 0.0022 16.8 2.4 1.4 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EKG16051.1 - 0.0012 17.7 0.5 0.0021 17.0 0.3 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EKG16051.1 - 0.01 14.9 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EKG16051.1 - 0.012 15.6 0.1 0.042 13.9 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EKG16051.1 - 0.012 15.3 0.4 0.021 14.5 0.3 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EKG16051.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.9 EKG16051.1 - 0.02 13.3 1.7 0.03 12.8 1.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EKG16051.1 - 0.045 13.3 1.4 0.1 12.2 1.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 EKG16051.1 - 0.081 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Rossmann-like PF10727.4 EKG16051.1 - 0.083 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain FAD_binding_3 PF01494.14 EKG16053.1 - 4.8e-05 22.5 1.9 0.00042 19.4 1.3 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG16053.1 - 0.00015 21.6 1.0 0.00032 20.6 0.7 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG16053.1 - 0.00029 19.8 3.5 0.00029 19.8 2.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG16053.1 - 0.00058 19.8 0.1 0.00085 19.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG16053.1 - 0.0008 19.2 0.6 0.0096 15.7 0.4 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EKG16053.1 - 0.0021 17.2 1.0 0.1 11.6 0.4 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EKG16053.1 - 0.0026 17.4 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EKG16053.1 - 0.0061 15.4 2.2 0.011 14.5 1.5 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EKG16053.1 - 0.031 12.7 0.5 0.046 12.1 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EKG16053.1 - 0.037 14.0 1.0 0.065 13.2 0.7 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG16053.1 - 0.044 12.7 0.9 0.38 9.6 0.4 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EKG16053.1 - 0.051 13.9 0.7 0.11 12.9 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG16053.1 - 0.063 12.3 0.3 0.1 11.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EKG16053.1 - 0.089 11.4 1.5 1.7 7.1 1.3 2.0 1 1 1 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EKG16053.1 - 0.091 11.5 0.2 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Peptidase_S8 PF00082.17 EKG16054.1 - 5.5e-14 51.9 0.1 1.2e-13 50.9 0.1 1.5 1 1 0 1 1 1 1 Subtilase family GMC_oxred_N PF00732.14 EKG16055.1 - 1.8e-56 191.4 0.0 1.2e-38 132.9 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG16055.1 - 3.6e-35 121.3 0.0 6.3e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EKG16055.1 - 3.3e-05 23.8 0.0 7.7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG16055.1 - 7.8e-05 21.7 0.0 0.00079 18.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EKG16055.1 - 0.0004 19.5 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EKG16055.1 - 0.00063 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EKG16055.1 - 0.003 16.4 0.0 0.046 12.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EKG16055.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG16055.1 - 0.016 15.0 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG16055.1 - 0.028 12.9 0.0 0.042 12.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.1 EKG16055.1 - 0.083 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EKG16055.1 - 0.1 12.6 0.1 0.69 9.9 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG16055.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Rabaptin PF03528.10 EKG16056.1 - 0.039 13.8 0.3 0.085 12.7 0.2 1.5 1 0 0 1 1 1 0 Rabaptin DUF544 PF04424.8 EKG16057.1 - 1e-13 51.1 0.0 1.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Macoilin PF09726.4 EKG16057.1 - 0.24 9.6 3.8 0.54 8.4 2.6 1.5 1 0 0 1 1 1 0 Transmembrane protein Gcd10p PF04189.8 EKG16058.1 - 1.4e-81 273.8 0.0 3.3e-81 272.7 0.0 1.6 2 0 0 2 2 2 1 Gcd10p family Histone PF00125.19 EKG16059.1 - 7.6e-30 102.8 0.4 9.5e-30 102.5 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EKG16059.1 - 6.9e-05 22.9 0.1 8.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EKG16059.1 - 0.008 16.2 1.0 0.012 15.6 0.7 1.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EKG16059.1 - 0.03 13.6 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DER1 PF04511.10 EKG16060.1 - 2.7e-50 170.6 4.8 3e-50 170.4 3.3 1.0 1 0 0 1 1 1 1 Der1-like family Glyco_hydro_18 PF00704.23 EKG16061.1 - 3.1e-12 46.6 1.6 4.5e-11 42.7 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Fungal_trans PF04082.13 EKG16062.1 - 0.0024 16.8 0.1 0.0061 15.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EKG16063.1 - 3.1e-25 88.5 0.5 5.5e-25 87.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG16063.1 - 2e-09 37.1 8.2 3.7e-09 36.3 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_deac_1 PF01522.16 EKG16064.1 - 5.6e-20 71.2 0.0 9.8e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EKG16064.1 - 2e-05 24.1 0.1 3.4e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) AAT PF03417.11 EKG16065.1 - 4.5e-33 114.5 0.0 5.4e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EKG16065.1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase GST_N_2 PF13409.1 EKG16066.1 - 1.1e-23 82.9 0.0 4e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG16066.1 - 2e-16 59.6 0.3 8.5e-16 57.6 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG16066.1 - 1.1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG16066.1 - 2.9e-05 24.2 0.0 0.00046 20.3 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG16066.1 - 0.00011 22.6 0.0 0.00025 21.4 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pro_isomerase PF00160.16 EKG16067.1 - 6.3e-40 136.9 0.0 1.2e-39 136.0 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MBOAT PF03062.14 EKG16068.1 - 3.9e-51 174.0 5.7 6.7e-51 173.3 4.0 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family XPA_C PF05181.7 EKG16069.1 - 2.6e-24 84.5 0.6 6.1e-24 83.3 0.4 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EKG16069.1 - 0.0016 18.0 2.8 0.0024 17.4 0.1 2.2 2 0 0 2 2 2 1 XPA protein N-terminal zf-dskA_traR PF01258.12 EKG16069.1 - 0.16 11.7 4.2 8.3 6.2 0.0 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger YhfH PF14149.1 EKG16069.1 - 0.39 10.5 5.1 0.6 9.9 0.8 2.5 2 0 0 2 2 2 0 YhfH-like protein TF_Zn_Ribbon PF08271.7 EKG16069.1 - 0.59 9.5 3.9 14 5.0 0.1 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 EKG16069.1 - 7.8 6.0 6.5 8.7 5.9 0.0 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit APH PF01636.18 EKG16072.1 - 3e-16 59.8 0.0 1.3e-15 57.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKG16072.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EKG16072.1 - 0.21 10.2 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Dscam_C PF12355.3 EKG16072.1 - 2.6 8.3 7.7 5 7.4 5.3 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal Nol1_Nop2_Fmu PF01189.12 EKG16073.1 - 6.6e-101 337.4 0.0 2.2e-100 335.6 0.0 1.8 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EKG16073.1 - 0.0024 17.4 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EKG16073.1 - 0.0035 16.9 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cofilin_ADF PF00241.15 EKG16074.1 - 4.3e-27 94.5 0.0 5.4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Sulfatase PF00884.18 EKG16074.1 - 0.025 13.7 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Sulfatase Cpn60_TCP1 PF00118.19 EKG16075.1 - 4.5e-116 388.3 5.9 5.1e-116 388.1 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_3 PF00933.16 EKG16078.1 - 3.3e-63 213.4 0.0 4.7e-63 212.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG16078.1 - 1.5e-43 148.9 0.2 2.4e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG16078.1 - 2.9e-06 27.1 0.0 6.5e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3805 PF12712.2 EKG16078.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3805) Glyco_hydro_31 PF01055.21 EKG16080.1 - 1e-75 255.2 0.0 1.3e-75 254.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 MFS_1 PF07690.11 EKG16081.1 - 1.9e-29 102.4 34.4 5.5e-29 100.9 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 EKG16081.1 - 0.0092 16.1 0.0 0.0092 16.1 0.0 3.9 3 2 0 4 4 4 1 NfeD-like C-terminal, partner-binding Zn_clus PF00172.13 EKG16082.1 - 0.00015 21.6 5.8 0.00027 20.7 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 EKG16084.1 - 0.00028 20.6 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.14 EKG16086.1 - 2.3e-06 26.9 0.0 5.1e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Big_4 PF07532.6 EKG16086.1 - 0.046 13.2 0.2 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 4) DUF3439 PF11921.3 EKG16086.1 - 0.11 12.2 0.6 0.18 11.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF4328 PF14219.1 EKG16088.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Acetyltransf_1 PF00583.19 EKG16089.1 - 5.1e-11 42.4 0.0 1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKG16089.1 - 2.8e-05 23.7 0.0 0.00015 21.4 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKG16089.1 - 0.00014 22.0 0.0 0.00021 21.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG16089.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG16089.1 - 0.0068 16.2 0.0 0.042 13.7 0.0 2.0 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 EKG16089.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKG16089.1 - 0.032 14.1 0.0 0.073 12.9 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HPP PF04982.8 EKG16090.1 - 4.1e-32 110.5 6.8 5.1e-32 110.2 4.7 1.1 1 0 0 1 1 1 1 HPP family WD40 PF00400.27 EKG16091.1 - 3e-70 229.7 13.0 2.4e-10 39.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EKG16091.1 - 1.6e-09 37.8 0.3 2.6e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 EKG16091.1 - 9.3e-05 20.7 1.8 0.38 8.8 0.0 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EKG16091.1 - 0.0015 17.3 0.2 0.21 10.3 0.0 2.8 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EKG16091.1 - 0.007 14.7 0.5 0.084 11.1 0.1 2.6 2 1 2 4 4 4 2 Cytochrome D1 heme domain Glycos_transf_1 PF00534.15 EKG16092.1 - 3.1e-22 78.8 0.0 6.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EKG16092.1 - 3.6e-09 36.8 0.0 3e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EKG16092.1 - 0.00012 22.2 0.0 0.00027 21.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF21 PF01595.15 EKG16093.1 - 3.4e-32 111.2 3.1 9.2e-32 109.8 2.4 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 EKG16093.1 - 0.00023 20.9 0.1 0.58 9.9 0.1 2.7 2 0 0 2 2 2 2 CBS domain Peptidase_S41 PF03572.13 EKG16094.1 - 7.9e-07 28.6 0.0 1.8e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 AAA_22 PF13401.1 EKG16095.1 - 2.3e-06 27.7 0.0 5.8e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG16095.1 - 6.8e-06 26.1 1.9 2.1e-05 24.5 1.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EKG16095.1 - 3.4e-05 23.5 0.0 7.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EKG16095.1 - 0.00014 20.8 0.0 0.00035 19.5 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 EKG16095.1 - 0.0037 16.9 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EKG16095.1 - 0.0046 17.7 0.5 0.015 16.1 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG16095.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKG16095.1 - 0.023 14.4 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EKG16095.1 - 0.044 13.9 0.1 0.65 10.1 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EKG16095.1 - 0.058 12.8 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EKG16095.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4535 PF15054.1 EKG16095.1 - 0.35 10.3 1.7 0.9 8.9 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) RNA_pol_3_Rpc31 PF11705.3 EKG16096.1 - 9.5 6.0 8.9 14 5.5 6.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 p450 PF00067.17 EKG16098.1 - 7.2e-70 235.7 0.0 9.3e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PNRC PF15365.1 EKG16099.1 - 2.4e-06 27.4 13.7 3.4e-06 26.9 1.4 4.0 4 0 0 4 4 4 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EKG16100.1 - 4.3e-14 52.3 0.5 5.4e-14 52.0 0.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EKG16100.1 - 5.6e-05 22.9 1.1 7.5e-05 22.5 0.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SPC12 PF06645.8 EKG16101.1 - 5.8e-24 83.7 1.6 1.5e-18 66.3 1.0 2.1 1 1 1 2 2 2 2 Microsomal signal peptidase 12 kDa subunit (SPC12) HELP PF03451.9 EKG16101.1 - 0.079 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 HELP motif CorA PF01544.13 EKG16102.1 - 4.4e-43 147.3 0.0 5.7e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Zn_clus PF00172.13 EKG16103.1 - 3e-09 36.6 11.3 3e-09 36.6 7.8 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.13 EKG16104.1 - 5.9e-13 48.6 0.1 1.4e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EKG16104.1 - 1.8e-05 24.4 1.2 2.7e-05 23.8 0.3 1.7 2 0 0 2 2 2 1 Barwin family Pollen_allerg_1 PF01357.16 EKG16104.1 - 0.0063 16.3 1.5 0.01 15.6 1.0 1.3 1 0 0 1 1 1 1 Pollen allergen BNR PF02012.15 EKG16104.1 - 0.057 13.2 1.1 0.057 13.2 0.8 2.2 2 0 0 2 2 2 0 BNR/Asp-box repeat His_Phos_2 PF00328.17 EKG16105.1 - 7.9e-19 68.1 0.0 1.6e-15 57.2 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) TcpQ PF10671.4 EKG16105.1 - 0.034 14.0 0.5 0.092 12.6 0.0 1.9 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Phlebovirus_G2 PF07245.6 EKG16106.1 - 0.31 9.2 4.1 0.4 8.9 2.9 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 F-box-like PF12937.2 EKG16107.1 - 2e-06 27.3 0.1 3.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG16107.1 - 0.00014 21.4 0.0 0.00029 20.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EKG16107.1 - 0.0029 17.2 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 F-box-like domain HET PF06985.6 EKG16109.1 - 6.6e-23 81.4 0.0 8.9e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TniQ PF06527.6 EKG16109.1 - 0.11 12.6 0.5 0.19 11.9 0.3 1.4 1 0 0 1 1 1 0 TniQ CorA PF01544.13 EKG16111.1 - 2.1e-05 23.6 0.1 4.8e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Neur_chan_memb PF02932.11 EKG16111.1 - 0.15 11.8 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APG17 PF04108.7 EKG16112.1 - 0.053 12.3 0.0 0.12 11.1 0.0 1.5 1 1 1 2 2 2 0 Autophagy protein Apg17 HMGL-like PF00682.14 EKG16116.1 - 5.7e-45 153.8 0.0 7.8e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like Iso_dh PF00180.15 EKG16117.1 - 5.4e-50 170.2 1.7 6.1e-50 170.1 1.2 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ank_2 PF12796.2 EKG16118.1 - 3.8e-39 132.9 3.9 1.8e-16 60.2 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG16118.1 - 3.2e-24 83.4 0.0 5.9e-09 35.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EKG16118.1 - 8.9e-20 68.8 0.0 0.00014 21.7 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EKG16118.1 - 1e-19 70.1 0.1 1.9e-09 37.4 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG16118.1 - 1e-19 70.4 0.1 3.4e-08 33.7 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Mago_nashi PF02792.9 EKG16118.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Mago nashi protein p450 PF00067.17 EKG16119.1 - 1.8e-69 234.4 0.0 2.2e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG16120.1 - 2.6e-31 108.6 0.0 3e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG16121.1 - 6.7e-27 94.4 2.1 1e-26 93.8 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG16121.1 - 1e-18 68.0 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG16121.1 - 2.5e-09 37.0 1.5 4.4e-09 36.2 1.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EKG16121.1 - 0.0016 18.0 0.3 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EKG16121.1 - 0.016 14.1 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EKG16121.1 - 0.043 13.6 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EKG16121.1 - 0.096 11.7 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain p450 PF00067.17 EKG16122.1 - 2.4e-08 32.9 0.1 3.5e-08 32.3 0.1 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EKG16123.1 - 9.2e-27 93.7 0.0 1.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EKG16123.1 - 7.7e-05 23.2 0.1 0.00023 21.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EKG16123.1 - 0.0032 16.8 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EKG16123.1 - 0.033 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_12 PF08242.7 EKG16123.1 - 0.075 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EKG16123.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase ketoacyl-synt PF00109.21 EKG16124.1 - 6.9e-21 74.8 0.7 1.6e-20 73.6 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EKG16124.1 - 8.6e-17 61.7 0.0 1.5e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EKG16124.1 - 6.4e-13 48.5 0.0 1.9e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EKG16124.1 - 5.6e-06 26.3 1.2 1.1e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Thiolase_N PF00108.18 EKG16124.1 - 0.001 18.1 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Aminotran_4 PF01063.14 EKG16125.1 - 2.6e-12 46.6 0.0 2.8e-07 30.2 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class IV Acyl_transf_1 PF00698.16 EKG16126.1 - 5.3e-30 104.8 0.2 8.8e-30 104.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain p450 PF00067.17 EKG16128.1 - 7.3e-20 70.9 0.0 1.9e-16 59.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EKG16129.1 - 6.9e-19 67.7 0.0 9.4e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4235 PF14019.1 EKG16129.1 - 0.042 13.6 0.1 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) MFS_1 PF07690.11 EKG16130.1 - 5.3e-30 104.3 39.8 8.7e-30 103.6 27.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG16130.1 - 0.00034 18.9 13.3 0.00043 18.6 9.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Condensation PF00668.15 EKG16131.1 - 0.059 12.2 0.1 0.13 11.1 0.1 1.5 1 1 0 1 1 1 0 Condensation domain AMP-binding PF00501.23 EKG16132.1 - 2.6e-176 586.0 1.4 7.3e-91 304.6 0.3 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EKG16132.1 - 2.2e-81 273.0 0.0 7.6e-31 107.0 0.0 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EKG16132.1 - 5.3e-20 71.4 0.0 1.7e-09 37.7 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG16132.1 - 8.5e-07 29.8 5.1 4.4e-05 24.3 0.0 3.9 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EKG16132.1 - 0.88 7.9 0.2 2.7 6.3 0.0 1.8 2 0 0 2 2 2 0 Transferase family Terminase_6 PF03237.10 EKG16132.1 - 0.97 8.1 0.0 5.7 5.5 0.0 2.0 2 0 0 2 2 2 0 Terminase-like family AATase PF07247.7 EKG16132.1 - 7.2 5.0 0.0 92 1.3 0.0 2.0 2 0 0 2 2 2 0 Alcohol acetyltransferase Peptidase_S10 PF00450.17 EKG16133.1 - 1.3e-73 248.5 0.0 1.5e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EKG16133.1 - 0.00034 20.5 1.6 0.0026 17.6 1.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Imm18 PF15566.1 EKG16133.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 18 p450 PF00067.17 EKG16134.1 - 3.9e-28 98.1 0.0 5.7e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG16135.1 - 3.1e-17 63.0 1.1 3.8e-17 62.7 0.3 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG16135.1 - 9.9e-08 31.8 0.4 6.2e-07 29.2 0.1 2.0 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EKG16135.1 - 0.0093 15.9 0.4 0.054 13.5 0.3 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG16135.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EKG16136.1 - 1.5e-29 102.8 0.0 1.9e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG16137.1 - 2.5e-10 39.4 0.0 3.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PAP2 PF01569.16 EKG16138.1 - 4.7e-16 58.6 1.9 4.7e-16 58.6 1.3 1.9 1 1 1 2 2 2 1 PAP2 superfamily Virul_fac_BrkB PF03631.10 EKG16138.1 - 0.0039 16.5 4.5 0.0062 15.9 3.1 1.3 1 0 0 1 1 1 1 Virulence factor BrkB 7TMR-DISM_7TM PF07695.6 EKG16138.1 - 0.019 14.6 3.2 2.2 7.8 3.4 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling Alpha-amylase PF00128.19 EKG16140.1 - 3.5e-60 204.0 3.1 4.4e-60 203.7 2.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EKG16140.1 - 1.9e-16 59.8 0.0 3.9e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_hydro_70 PF02324.11 EKG16140.1 - 0.0019 16.1 0.8 0.51 8.0 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 70 Alpha-amylase PF00128.19 EKG16141.1 - 9.8e-16 58.0 5.0 1.7e-14 53.9 3.2 2.8 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EKG16141.1 - 1.1e-14 54.4 0.1 2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.1 EKG16141.1 - 5.8e-07 29.7 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EKG16141.1 - 8.4e-07 28.5 0.0 1.5e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EKG16141.1 - 0.041 14.4 1.8 0.083 13.5 0.8 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain Spo12 PF05032.7 EKG16142.1 - 7.6e-08 31.8 0.3 2.1e-07 30.4 0.1 1.8 2 0 0 2 2 2 1 Spo12 family p450 PF00067.17 EKG16143.1 - 7.9e-65 219.1 0.0 1.4e-64 218.3 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_S10 PF00338.17 EKG16144.1 - 1.1e-20 73.3 0.0 1.5e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e TRAPP PF04051.11 EKG16145.1 - 7.1e-42 142.4 0.0 8.5e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_N PF00056.18 EKG16147.1 - 3.2e-44 150.1 0.0 4.8e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EKG16147.1 - 2.9e-40 137.8 0.0 3.9e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EKG16147.1 - 0.0012 17.5 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CBFD_NFYB_HMF PF00808.18 EKG16148.1 - 1.8e-19 69.5 0.6 2.5e-19 69.0 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKG16148.1 - 3.6e-11 43.0 0.1 5.5e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EKG16148.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF2370 PF10176.4 EKG16148.1 - 0.13 11.5 3.0 0.25 10.6 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) PNP_UDP_1 PF01048.15 EKG16149.1 - 6.2e-53 179.1 0.1 8.8e-53 178.6 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily SKG6 PF08693.5 EKG16150.1 - 0.045 13.0 0.4 0.045 13.0 0.3 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Gly-zipper_YMGG PF13441.1 EKG16150.1 - 0.052 13.0 2.2 0.09 12.3 1.5 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EKG16150.1 - 0.06 12.9 3.4 0.1 12.2 2.3 1.3 1 0 0 1 1 1 0 Glycine zipper PDGLE PF13190.1 EKG16150.1 - 0.1 12.2 2.4 0.19 11.4 0.1 2.4 2 0 0 2 2 2 0 PDGLE domain Fungal_trans PF04082.13 EKG16152.1 - 8.4e-08 31.4 0.0 1.6e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 EKG16153.1 - 1.5e-38 132.6 1.6 4.6e-33 114.5 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG16153.1 - 4.6e-07 29.9 0.0 0.019 14.8 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG16153.1 - 5.3e-06 26.3 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG16153.1 - 1.4e-05 24.8 0.0 0.0079 15.9 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG16153.1 - 6.4e-05 23.1 0.0 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EKG16153.1 - 0.00088 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 ThiF family NAD_binding_10 PF13460.1 EKG16153.1 - 0.0012 18.8 0.1 0.68 9.9 0.0 2.4 2 0 0 2 2 2 2 NADH(P)-binding FAD_binding_3 PF01494.14 EKG16153.1 - 0.002 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EKG16153.1 - 0.0052 15.6 0.0 0.099 11.4 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EKG16153.1 - 0.01 16.2 0.0 0.044 14.1 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG16153.1 - 0.022 13.6 0.4 0.77 8.5 0.0 2.3 2 1 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 EKG16153.1 - 0.028 13.7 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EKG16153.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EKG16153.1 - 0.045 12.2 0.1 0.31 9.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 EKG16153.1 - 0.049 13.0 0.0 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DHquinase_II PF01220.14 EKG16153.1 - 0.06 12.6 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Dehydroquinase class II Shikimate_DH PF01488.15 EKG16153.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TauE PF01925.14 EKG16154.1 - 0.00061 19.3 4.0 0.0026 17.2 0.3 2.0 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE Peptidase_M22 PF00814.20 EKG16156.1 - 8.1e-87 291.1 0.0 9.3e-87 290.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 EKG16156.1 - 0.18 11.3 0.0 0.71 9.3 0.0 1.8 2 0 0 2 2 2 0 Staygreen protein SET PF00856.23 EKG16157.1 - 1.9e-13 51.0 0.0 4.1e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 SET domain Campylo_MOMP PF05538.6 EKG16157.1 - 0.13 10.6 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Campylobacter major outer membrane protein EPL1 PF10513.4 EKG16158.1 - 9.9e-34 116.8 0.0 9.9e-34 116.8 0.0 3.0 3 1 0 3 3 3 1 Enhancer of polycomb-like AMPKBI PF04739.10 EKG16159.1 - 7.6e-29 99.5 1.3 7.6e-29 99.5 0.9 2.5 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain Kin17_mid PF10357.4 EKG16161.1 - 1.9e-49 166.5 0.3 1.9e-49 166.5 0.2 1.7 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EKG16161.1 - 0.00055 19.9 0.3 0.0011 19.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG16161.1 - 0.017 15.3 0.7 0.033 14.3 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EKG16161.1 - 0.053 13.6 1.5 0.18 11.9 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Gly_transf_sug PF04488.10 EKG16162.1 - 1.5e-17 63.8 0.0 2.3e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EKG16162.1 - 0.0077 14.7 4.0 0.32 9.4 0.3 2.0 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain AtpR PF12966.2 EKG16162.1 - 0.065 13.3 2.3 0.18 11.9 1.6 1.7 1 0 0 1 1 1 0 N-ATPase, AtpR subunit SMI1_KNR4 PF09346.5 EKG16163.1 - 1.2e-32 112.6 0.0 2.3e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) adh_short PF00106.20 EKG16164.1 - 3.2e-08 33.6 0.1 6.2e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG16164.1 - 1.9e-05 24.5 0.0 4.4e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG16164.1 - 0.00045 19.9 0.0 0.0039 16.8 0.0 2.0 1 1 1 2 2 2 1 KR domain Bmp PF02608.9 EKG16164.1 - 0.2 10.3 0.3 0.27 9.9 0.2 1.1 1 0 0 1 1 1 0 Basic membrane protein Sec1 PF00995.18 EKG16165.1 - 1.9e-151 505.5 0.1 2.2e-151 505.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family DLH PF01738.13 EKG16165.1 - 3.2e-28 98.4 0.3 4.9e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG16165.1 - 6.3e-09 35.7 0.2 4.7e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG16165.1 - 0.083 12.4 0.3 3.6 7.0 0.0 2.9 3 0 0 3 3 3 0 alpha/beta hydrolase fold ABC_membrane PF00664.18 EKG16166.1 - 1.1e-88 297.2 37.1 5.9e-47 160.3 6.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EKG16166.1 - 8.2e-50 168.6 0.2 5e-31 107.8 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EKG16166.1 - 6.3e-08 32.1 1.4 8.8e-05 21.8 0.1 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EKG16166.1 - 1.2e-07 31.1 4.5 0.00056 19.3 0.3 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EKG16166.1 - 3.9e-07 30.8 0.1 0.027 15.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EKG16166.1 - 6.8e-07 29.5 1.0 1.1 9.2 0.0 3.3 2 1 1 3 3 3 3 AAA domain DUF258 PF03193.11 EKG16166.1 - 6.8e-07 28.6 0.1 0.096 11.8 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG16166.1 - 6.6e-06 26.2 0.8 0.071 13.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EKG16166.1 - 9.6e-05 21.8 0.0 0.68 9.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKG16166.1 - 0.0011 19.1 1.8 2.7 8.1 0.0 3.5 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG16166.1 - 0.0013 18.9 0.5 2.9 8.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EKG16166.1 - 0.002 17.7 1.2 1.1 8.7 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EKG16166.1 - 0.0027 17.5 0.0 4.1 7.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EKG16166.1 - 0.0035 16.3 0.4 1.5 7.6 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EKG16166.1 - 0.0083 15.8 0.1 5.8 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 EKG16166.1 - 0.011 14.3 1.4 0.022 13.3 0.1 2.1 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_28 PF13521.1 EKG16166.1 - 0.019 14.9 3.7 0.62 10.0 0.1 3.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.1 EKG16166.1 - 0.022 14.6 0.1 3 7.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EKG16166.1 - 0.026 14.2 1.1 2.5 7.9 0.1 2.9 2 0 0 2 2 2 0 Part of AAA domain CDC45 PF02724.9 EKG16166.1 - 0.03 12.3 3.7 0.047 11.7 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 EKG16166.1 - 0.041 14.0 0.1 11 6.2 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EKG16166.1 - 0.073 11.7 1.2 8 5.0 0.0 2.6 2 1 0 2 2 2 0 G-protein alpha subunit MobB PF03205.9 EKG16166.1 - 0.086 12.5 0.2 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EKG16166.1 - 0.093 12.3 0.2 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.12 EKG16166.1 - 0.18 11.5 6.3 2.5 7.8 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EKG16166.1 - 0.34 10.8 1.4 12 5.8 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EKG16166.1 - 3.6 7.8 10.0 9.1 6.5 0.2 3.5 3 1 0 3 3 2 0 AAA domain AAA_10 PF12846.2 EKG16166.1 - 5.5 6.3 9.4 11 5.3 0.2 3.4 4 0 0 4 4 3 0 AAA-like domain RRM_1 PF00076.17 EKG16167.1 - 9.4e-08 31.5 0.2 2.3e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG16167.1 - 4.5e-05 23.2 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG16167.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EKG16167.1 - 0.0034 17.0 0.6 0.0058 16.2 0.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nup35_RRM_2 PF14605.1 EKG16167.1 - 0.0092 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TPR_11 PF13414.1 EKG16168.1 - 4.4e-33 112.7 36.1 2.2e-07 30.4 0.0 10.5 9 2 3 12 12 12 6 TPR repeat TPR_2 PF07719.12 EKG16168.1 - 3.3e-30 101.5 39.9 0.0002 21.0 0.0 12.7 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_1 PF00515.23 EKG16168.1 - 7.1e-30 101.3 38.1 4.5e-05 22.8 0.1 11.5 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 EKG16168.1 - 1.3e-29 101.9 30.6 4.7e-07 29.6 1.0 10.3 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_19 PF14559.1 EKG16168.1 - 2.3e-21 75.8 37.0 0.00017 21.8 0.3 10.4 10 3 3 13 13 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 EKG16168.1 - 4e-20 70.4 25.5 0.0083 16.6 0.0 13.4 11 4 5 16 16 14 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKG16168.1 - 1.1e-18 67.3 35.9 5.7e-06 26.8 0.0 10.8 8 3 3 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.1 EKG16168.1 - 3.7e-18 63.8 35.4 0.0018 17.9 0.2 10.7 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_6 PF13174.1 EKG16168.1 - 8.5e-14 50.9 35.4 0.028 14.8 0.1 13.4 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG16168.1 - 4.9e-13 47.8 29.1 0.0026 17.4 0.1 11.7 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 EKG16168.1 - 2.4e-11 42.8 15.4 1.2 9.5 0.0 11.2 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG16168.1 - 7.7e-08 32.0 5.8 0.007 16.1 0.1 6.6 4 2 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKG16168.1 - 1.6e-07 31.0 16.1 0.0002 21.1 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG16168.1 - 5.2e-06 26.4 22.0 0.099 12.7 0.9 6.6 6 1 0 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 EKG16168.1 - 0.014 15.1 1.2 0.014 15.1 0.8 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat PAN_4 PF14295.1 EKG16169.1 - 5.7e-05 22.7 0.5 0.00012 21.6 0.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EKG16169.1 - 0.043 13.4 0.4 0.15 11.7 0.3 1.9 1 0 0 1 1 1 0 PAN-like domain DUF2305 PF10230.4 EKG16170.1 - 6.3e-46 156.9 0.0 4.1e-22 78.8 0.0 3.7 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EKG16170.1 - 6.4e-05 22.7 0.2 0.00011 21.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG16170.1 - 0.00055 19.8 2.6 0.0012 18.7 1.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EKG16170.1 - 0.036 13.6 0.1 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DCP1 PF06058.8 EKG16171.1 - 1.3e-15 57.5 0.0 2.9e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 EKG16172.1 - 6.7e-16 58.9 0.0 1e-15 58.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAD_binding_4 PF01565.18 EKG16174.1 - 3.8e-26 91.2 1.1 1.1e-25 89.6 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain STE3 PF02076.10 EKG16175.1 - 1.6e-74 250.5 5.8 2.1e-74 250.1 4.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor ATG22 PF11700.3 EKG16177.1 - 7.5e-88 295.1 21.6 8.5e-88 294.9 15.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EKG16177.1 - 3.2e-13 49.1 34.7 1e-08 34.3 14.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily PspC PF04024.7 EKG16177.1 - 0.12 11.8 1.1 0.27 10.7 0.2 2.0 2 0 0 2 2 2 0 PspC domain DAP10 PF07213.6 EKG16177.1 - 1.1 9.0 6.2 11 5.8 0.2 2.7 2 0 0 2 2 2 0 DAP10 membrane protein HGTP_anticodon2 PF12745.2 EKG16178.1 - 5.6e-79 265.1 6.2 7.9e-77 258.0 0.0 2.9 2 1 1 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EKG16178.1 - 9.9e-78 260.8 0.0 8.7e-37 126.6 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EKG16178.1 - 5.6e-45 153.4 0.0 2.3e-18 66.1 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EKG16178.1 - 2.4e-16 59.6 0.1 5.2e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EKG16178.1 - 3.4e-13 49.3 0.1 1.6e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 Histidyl-tRNA synthetase APH PF01636.18 EKG16178.1 - 0.00015 21.6 1.2 0.0034 17.1 0.0 2.9 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG16178.1 - 0.00072 18.6 0.0 0.74 8.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like DUF445 PF04286.7 EKG16178.1 - 0.044 13.3 7.2 0.09 12.2 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Cut12 PF11500.3 EKG16179.1 - 4.5e-23 81.6 15.7 4.5e-23 81.6 10.8 1.9 2 0 0 2 2 2 1 Spindle pole body formation-associated protein AA_permease_2 PF13520.1 EKG16180.1 - 2.1e-64 217.6 34.5 2.7e-64 217.2 23.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG16180.1 - 1.5e-17 63.0 34.5 3.9e-17 61.7 23.9 1.6 1 1 0 1 1 1 1 Amino acid permease DUF2963 PF11178.3 EKG16181.1 - 0.18 11.2 1.4 0.24 10.8 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) UQ_con PF00179.21 EKG16182.1 - 9e-41 138.5 0.0 1.2e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG16182.1 - 0.014 15.1 0.0 0.061 13.0 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EKG16182.1 - 0.12 12.2 0.4 0.22 11.4 0.3 1.6 1 1 0 1 1 1 0 RWD domain Ytp1 PF10355.4 EKG16184.1 - 1.9e-85 286.3 13.6 1.9e-85 286.3 9.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EKG16184.1 - 2e-31 107.6 0.4 2e-31 107.6 0.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF4225 PF13988.1 EKG16184.1 - 0.19 11.1 0.4 0.7 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) NPP1 PF05630.6 EKG16185.1 - 5.4e-08 32.8 0.0 7.1e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF2404 PF10296.4 EKG16186.1 - 5.9e-05 23.1 0.0 0.00017 21.6 0.0 1.8 1 1 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) adh_short PF00106.20 EKG16187.1 - 1.6e-20 73.6 0.1 2.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG16187.1 - 5.6e-09 35.9 0.0 7.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG16187.1 - 2.7e-08 33.8 0.0 3.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EKG16188.1 - 1.2e-129 432.6 0.0 1.4e-129 432.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EKG16188.1 - 0.0001 22.3 0.0 0.00024 21.2 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EKG16188.1 - 0.00029 20.8 0.3 0.00059 19.8 0.1 1.5 2 0 0 2 2 2 1 NADH(P)-binding IlvN PF07991.7 EKG16188.1 - 0.00064 19.1 0.3 0.11 11.8 0.0 3.0 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 EKG16188.1 - 0.023 15.2 0.0 0.041 14.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold XdhC_C PF13478.1 EKG16188.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 EKG16188.1 - 0.067 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DER1 PF04511.10 EKG16189.1 - 2.3e-28 99.0 5.4 2.7e-28 98.8 3.7 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 EKG16189.1 - 0.013 15.5 7.1 0.028 14.4 4.9 1.6 1 1 0 1 1 1 0 Rhomboid family DKCLD PF08068.7 EKG16190.1 - 2.1e-26 91.6 0.2 1.7e-25 88.6 0.2 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EKG16190.1 - 3.9e-23 82.2 4.2 2e-21 76.7 0.1 3.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EKG16190.1 - 1.5e-21 75.8 1.9 3.1e-21 74.8 1.3 1.6 1 0 0 1 1 1 1 PUA domain NSP2_assoc PF14758.1 EKG16190.1 - 0.005 16.9 0.5 0.0093 16.1 0.1 1.5 1 1 0 1 1 1 1 Non-essential region of nsp2 of arterivirus polyprotein SOBP PF15279.1 EKG16190.1 - 0.3 11.4 11.3 0.48 10.7 7.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DnaJ PF00226.26 EKG16191.1 - 7.9e-28 95.9 1.8 1.3e-27 95.2 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EKG16191.1 - 2.6e-18 65.6 2.3 5.7e-17 61.3 0.1 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain NPP1 PF05630.6 EKG16193.1 - 1.9e-63 213.9 0.0 2.8e-63 213.3 0.0 1.3 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Beta-APP PF03494.8 EKG16193.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Abhydrolase_6 PF12697.2 EKG16194.1 - 1e-24 87.6 1.0 1.3e-24 87.4 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG16194.1 - 1.2e-11 44.5 0.0 1.8e-11 43.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tho2 PF11262.3 EKG16197.1 - 1.2e-87 293.6 0.3 2.5e-87 292.6 0.2 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EKG16197.1 - 4.7e-30 103.1 0.0 1.2e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PAM2 PF07145.10 EKG16197.1 - 0.014 14.8 0.3 0.037 13.5 0.2 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Aminotran_1_2 PF00155.16 EKG16198.1 - 1.4e-83 280.9 0.0 1.8e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EKG16198.1 - 2.8e-06 25.8 0.0 4.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EKG16198.1 - 1e-05 24.4 0.0 2.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EKG16198.1 - 0.0072 15.4 0.2 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3405 PF11885.3 EKG16198.1 - 0.15 10.2 0.4 0.23 9.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) SNF2_N PF00176.18 EKG16199.1 - 1.6e-47 161.7 0.3 2.6e-47 161.0 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG16199.1 - 3.3e-18 65.3 0.0 2.9e-17 62.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG16199.1 - 7.7e-06 25.8 0.2 4.9e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EKG16199.1 - 0.052 13.4 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain UDPG_MGDP_dh_N PF03721.9 EKG16199.1 - 0.21 10.9 0.0 0.49 9.7 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GSH_synth_ATP PF03917.12 EKG16200.1 - 1.6e-110 369.2 0.0 2e-110 368.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EKG16200.1 - 5.3e-36 122.9 0.0 8.8e-36 122.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF4203 PF13886.1 EKG16201.1 - 2.1e-37 128.6 24.8 2.8e-37 128.2 17.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Mucin PF01456.12 EKG16201.1 - 0.0014 18.4 15.8 0.0014 18.4 10.9 2.2 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF4051 PF13260.1 EKG16201.1 - 0.093 12.0 0.3 0.24 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Erf4 PF10256.4 EKG16202.1 - 4e-30 104.0 0.0 4.9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_12 PF13424.1 EKG16204.1 - 6.9e-25 86.8 21.3 1.7e-06 27.8 0.1 7.8 6 1 1 8 8 7 5 Tetratricopeptide repeat TPR_10 PF13374.1 EKG16204.1 - 8.5e-12 44.5 29.6 0.037 13.9 0.1 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 EKG16204.1 - 8.9e-11 41.2 11.7 0.00069 19.2 0.0 7.4 6 1 3 9 9 8 2 TPR repeat TPR_7 PF13176.1 EKG16204.1 - 4.2e-09 35.5 13.3 0.79 9.6 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKG16204.1 - 3.7e-08 32.5 8.9 0.58 10.0 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKG16204.1 - 2.3e-07 30.1 21.4 0.14 11.7 0.1 8.8 10 0 0 10 10 9 3 Tetratricopeptide repeat NACHT PF05729.7 EKG16204.1 - 2.5e-07 30.5 0.0 6.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_14 PF13428.1 EKG16204.1 - 3.7e-07 30.2 20.5 0.47 11.2 0.0 10.6 9 2 3 12 12 9 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG16204.1 - 1e-06 28.1 37.8 0.55 10.2 0.1 11.6 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_16 PF13432.1 EKG16204.1 - 3.4e-06 27.5 20.8 0.11 13.1 0.0 8.0 7 1 2 9 9 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG16204.1 - 1.1e-05 25.4 10.4 0.0052 16.8 0.3 5.9 3 2 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EKG16204.1 - 8.9e-05 22.7 6.1 12 6.2 0.0 7.0 6 2 2 8 8 8 0 Tetratricopeptide repeat AAA_22 PF13401.1 EKG16204.1 - 0.0001 22.4 0.2 0.002 18.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF3856 PF12968.2 EKG16204.1 - 0.0006 19.6 2.6 2.8 7.7 0.1 4.3 4 0 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 EKG16204.1 - 0.0015 18.8 11.9 7.9 7.1 0.0 8.0 10 0 0 10 10 5 0 Tetratricopeptide repeat AAA_16 PF13191.1 EKG16204.1 - 0.0027 17.7 4.4 0.0042 17.1 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain PPR PF01535.15 EKG16204.1 - 0.0057 16.5 3.3 9.3 6.4 0.0 5.9 7 0 0 7 7 4 0 PPR repeat AAA_30 PF13604.1 EKG16204.1 - 0.028 14.0 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sel1 PF08238.7 EKG16204.1 - 0.048 14.3 0.9 1.9 9.2 0.0 3.9 4 0 0 4 4 2 0 Sel1 repeat SPOB_a PF14689.1 EKG16204.1 - 0.076 12.5 0.0 4.3 6.9 0.0 3.0 3 0 0 3 3 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain AAA PF00004.24 EKG16204.1 - 0.088 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EKG16204.1 - 0.11 11.3 0.0 0.36 9.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Cullin PF00888.17 EKG16204.1 - 0.11 10.9 2.1 0.26 9.7 0.0 2.2 3 0 0 3 3 3 0 Cullin family ABC_tran PF00005.22 EKG16204.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 EKG16204.1 - 0.24 10.1 0.0 0.51 9.0 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 EKG16204.1 - 0.3 10.9 2.6 0.49 10.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain His_biosynth PF00977.16 EKG16205.1 - 7e-34 117.0 0.0 8.5e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.12 EKG16205.1 - 0.13 11.3 0.1 5.4 6.1 0.1 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI DUF4602 PF15375.1 EKG16206.1 - 0.0055 16.7 23.7 0.0055 16.7 16.4 3.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) Bac_Ubq_Cox PF01654.12 EKG16207.1 - 0.026 12.9 5.3 0.04 12.3 3.7 1.2 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase Ribosomal_L2_C PF03947.13 EKG16208.1 - 1.7e-37 128.1 3.5 1.7e-37 128.1 2.4 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EKG16208.1 - 9e-14 51.2 0.1 1.8e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain BAR PF03114.13 EKG16209.1 - 6.7e-45 153.3 6.7 8e-45 153.1 4.6 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EKG16209.1 - 1.9e-08 33.6 2.6 2.2e-08 33.3 1.8 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PMEI PF04043.10 EKG16209.1 - 0.0051 16.7 4.3 0.066 13.1 0.6 2.4 1 1 1 2 2 2 1 Plant invertase/pectin methylesterase inhibitor DUF1501 PF07394.7 EKG16209.1 - 0.01 14.6 0.8 0.015 14.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) GBP_C PF02841.9 EKG16209.1 - 0.028 13.6 9.8 0.045 12.9 6.8 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Meiosis_expr PF15163.1 EKG16209.1 - 0.033 14.5 1.7 0.11 12.8 1.2 1.9 1 0 0 1 1 1 0 Meiosis-expressed Stirrup PF09061.1 EKG16209.1 - 0.12 12.3 0.1 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Stirrup APG6 PF04111.7 EKG16209.1 - 0.4 9.6 11.5 0.54 9.2 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 MscS_TM PF12794.2 EKG16209.1 - 1.3 7.5 5.0 2 6.9 3.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 IncA PF04156.9 EKG16209.1 - 6.8 6.2 9.1 14 5.2 6.3 1.5 1 0 0 1 1 1 0 IncA protein SNF2_N PF00176.18 EKG16210.1 - 3.3e-84 282.2 1.8 3.3e-84 282.2 1.2 2.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EKG16210.1 - 1.7e-23 82.3 1.3 4.6e-23 80.9 0.2 2.3 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EKG16210.1 - 1.1e-18 66.8 0.1 1.7e-16 59.8 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EKG16210.1 - 3.1e-17 62.5 2.1 3.1e-17 62.5 1.4 3.3 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EKG16210.1 - 3.2e-11 42.8 14.6 3.2e-11 42.8 10.1 2.7 2 0 0 2 2 2 1 HSA QLQ PF08880.6 EKG16210.1 - 2.1e-08 33.4 1.6 2.1e-08 33.4 1.1 2.9 3 0 0 3 3 3 1 QLQ DUF3138 PF11336.3 EKG16210.1 - 5.4 5.0 11.8 11 4.0 8.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2423 PF10338.4 EKG16212.1 - 5.8e-17 61.3 0.9 8.3e-17 60.8 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) PINIT PF14324.1 EKG16213.1 - 1.2e-38 132.4 0.0 2.1e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EKG16213.1 - 1.9e-17 62.4 2.4 3e-17 61.8 1.7 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EKG16213.1 - 4.4e-09 35.6 0.1 9.4e-09 34.5 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EKG16213.1 - 2.9e-05 23.4 1.1 6e-05 22.4 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DDR PF08841.5 EKG16213.1 - 0.15 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain zf-C3HC4_3 PF13920.1 EKG16213.1 - 0.2 11.3 1.7 0.39 10.4 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FA_hydroxylase PF04116.8 EKG16215.1 - 3.4e-13 50.0 20.7 3.4e-13 50.0 14.3 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_9 PF10081.4 EKG16215.1 - 0.035 12.8 0.3 0.049 12.3 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family zf-C2H2 PF00096.21 EKG16218.1 - 2.8e-18 65.0 21.1 0.00014 22.0 0.6 5.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG16218.1 - 6.7e-17 60.8 30.4 9.1e-09 35.1 0.3 5.3 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG16218.1 - 9.7e-13 47.4 17.6 0.0019 18.3 0.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EKG16218.1 - 0.0023 18.0 8.5 0.53 10.5 0.3 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type CHORD PF04968.7 EKG16218.1 - 1.1 9.5 10.7 3.8 7.8 0.1 3.8 1 1 3 4 4 4 0 CHORD MFS_1 PF07690.11 EKG16220.1 - 1.3e-33 116.1 47.1 1.3e-33 116.1 32.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG16220.1 - 3.1e-19 68.6 12.2 3.1e-19 68.6 7.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG16220.1 - 1.2e-08 33.9 26.7 3.1e-08 32.6 10.7 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter Herpes_glycop_D PF01537.12 EKG16221.1 - 0.093 12.6 0.2 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus glycoprotein D/GG/GX domain OPT PF03169.10 EKG16222.1 - 2.5e-103 346.6 29.4 2.7e-102 343.2 20.4 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein BatA PF07584.6 EKG16222.1 - 3.2 8.0 6.2 23 5.2 0.4 3.6 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal PALP PF00291.20 EKG16223.1 - 1.3e-56 192.1 1.0 1.5e-56 191.8 0.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Eno-Rase_NADH_b PF12242.3 EKG16223.1 - 0.036 13.8 0.3 5.5 6.8 0.1 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF108 PF01958.13 EKG16223.1 - 0.078 13.2 0.2 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF108 Amidohydro_2 PF04909.9 EKG16224.1 - 2.2e-22 79.9 0.5 3.3e-21 76.0 0.4 2.1 1 1 0 1 1 1 1 Amidohydrolase PLDc_2 PF13091.1 EKG16224.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain SnoaL_4 PF13577.1 EKG16225.1 - 6.5e-26 90.7 0.4 9.5e-26 90.1 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain PSK_trans_fac PF07704.6 EKG16225.1 - 0.027 15.1 0.2 0.11 13.1 0.1 1.9 2 0 0 2 2 2 0 Rv0623-like transcription factor PAH PF02671.16 EKG16225.1 - 0.038 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 Paired amphipathic helix repeat Zn_clus PF00172.13 EKG16226.1 - 2.1e-05 24.3 12.2 3.9e-05 23.4 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EKG16226.1 - 0.0052 17.1 0.8 0.0052 17.1 0.6 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein zinc_ribbon_6 PF14599.1 EKG16226.1 - 0.15 11.8 1.7 0.3 10.9 1.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon Fungal_trans PF04082.13 EKG16227.1 - 2.2e-18 66.0 0.0 3.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPE65 PF03055.10 EKG16229.1 - 3.6e-80 269.8 0.0 4.3e-80 269.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Amidohydro_1 PF01979.15 EKG16230.1 - 1.1e-28 100.9 0.4 1.5e-28 100.4 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG16230.1 - 1.3e-11 45.0 1.5 1.7e-11 44.7 1.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG16230.1 - 6.1e-11 42.1 0.3 7.3e-11 41.9 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Bac_rhamnosid PF05592.6 EKG16231.1 - 2.5e-184 613.2 0.0 3.2e-184 612.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EKG16231.1 - 5.9e-58 195.1 2.3 7.3e-58 194.8 0.1 2.0 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain DUF3344 PF11824.3 EKG16231.1 - 0.048 13.0 0.1 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Sugar_tr PF00083.19 EKG16232.1 - 3.2e-40 138.0 10.9 3.7e-40 137.8 7.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG16232.1 - 8.4e-12 44.4 17.2 1e-11 44.1 11.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16233.1 - 2.2e-23 82.5 9.3 2.6e-23 82.3 6.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG16233.1 - 0.0011 17.7 5.4 0.0014 17.4 3.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sigma70_r4 PF04545.11 EKG16233.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Fungal_trans PF04082.13 EKG16235.1 - 1.1e-06 27.7 0.0 1.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fip1 PF05182.8 EKG16235.1 - 0.36 10.1 2.6 0.88 8.8 0.1 2.2 2 0 0 2 2 2 0 Fip1 motif FAD_binding_3 PF01494.14 EKG16236.1 - 1.7e-13 50.4 1.0 3.3e-09 36.2 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EKG16236.1 - 0.013 14.4 0.4 0.077 11.8 0.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EKG16236.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG16236.1 - 0.052 13.5 0.1 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EKG16236.1 - 0.052 12.9 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 EKG16236.1 - 0.06 13.3 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EKG16236.1 - 0.066 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EKG16236.1 - 0.13 11.9 0.1 0.66 9.7 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding CsbD PF05532.7 EKG16237.1 - 0.04 13.6 0.2 0.089 12.4 0.2 1.5 1 0 0 1 1 1 0 CsbD-like Glyco_hydro_32N PF00251.15 EKG16238.1 - 1.5e-42 146.0 0.5 2.1e-42 145.5 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EKG16238.1 - 6.8e-13 48.8 0.0 1.3e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 EKG16238.1 - 0.0056 16.0 1.1 0.078 12.2 0.0 2.2 2 0 0 2 2 2 1 BNR repeat-like domain Peptidase_S15 PF02129.13 EKG16239.1 - 7e-43 147.0 0.5 7.9e-40 136.9 0.1 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FAD_binding_3 PF01494.14 EKG16240.1 - 1.2e-71 241.6 0.0 1.7e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EKG16240.1 - 0.007 16.4 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG16240.1 - 0.033 14.0 0.0 0.16 11.8 0.0 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG16240.1 - 0.039 13.9 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG16240.1 - 0.067 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family RPE65 PF03055.10 EKG16241.1 - 4.5e-125 417.9 0.0 5.1e-125 417.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Abhydrolase_3 PF07859.8 EKG16242.1 - 2e-15 56.9 0.1 2.5e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG16242.1 - 2.5e-07 29.8 0.2 2.8e-05 23.0 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EKG16242.1 - 5.2e-06 26.2 0.0 6.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EKG16242.1 - 1.1e-05 24.4 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EKG16242.1 - 0.0015 17.3 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.20 EKG16242.1 - 0.0098 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EKG16242.1 - 0.023 14.5 0.1 0.028 14.3 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG16242.1 - 0.1 11.8 0.1 0.72 9.0 0.1 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF1350 PF07082.6 EKG16242.1 - 0.15 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) DUF4645 PF15488.1 EKG16243.1 - 0.034 13.3 0.1 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4645) adh_short PF00106.20 EKG16246.1 - 4.8e-17 62.3 1.0 2.3e-16 60.1 0.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG16246.1 - 0.00012 21.7 2.2 0.097 12.3 0.0 2.6 2 1 0 2 2 2 2 KR domain Epimerase PF01370.16 EKG16246.1 - 0.00029 20.3 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG16246.1 - 0.0012 18.8 0.0 0.0071 16.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKG16246.1 - 0.0015 18.2 0.3 0.0033 17.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ank_2 PF12796.2 EKG16247.1 - 1.1e-82 272.4 34.9 2.1e-16 60.0 0.8 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EKG16247.1 - 2.2e-50 166.0 27.6 3.1e-06 26.7 0.0 10.0 11 0 0 11 11 11 9 Ankyrin repeat Ank_4 PF13637.1 EKG16247.1 - 4.2e-37 125.8 11.0 3.3e-07 30.6 0.0 7.9 2 1 7 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG16247.1 - 4.8e-31 103.7 7.8 0.0069 16.5 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EKG16247.1 - 2.4e-27 94.3 24.3 6.4e-06 26.2 0.1 9.1 1 1 9 10 10 10 9 Ankyrin repeats (many copies) p450 PF00067.17 EKG16248.1 - 4.8e-06 25.3 0.0 4.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EcsC PF12787.2 EKG16248.1 - 0.054 12.8 0.0 0.061 12.7 0.0 1.0 1 0 0 1 1 1 0 EcsC protein family HisKA PF00512.20 EKG16248.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF3583 PF12126.3 EKG16248.1 - 0.12 11.3 0.1 0.13 11.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) p450 PF00067.17 EKG16250.1 - 1.3e-16 60.1 0.0 1.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG16251.1 - 3.6e-28 98.3 0.0 5.2e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG16252.1 - 1.2e-53 182.2 0.0 1.4e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cortex-I_coil PF09304.5 EKG16254.1 - 0.00046 20.1 6.0 0.00046 20.1 4.1 2.8 2 1 0 2 2 2 1 Cortexillin I, coiled coil GAS PF13851.1 EKG16254.1 - 0.0016 17.6 16.7 0.072 12.2 5.1 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EKG16254.1 - 0.012 14.6 18.1 0.11 11.5 5.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 EKG16254.1 - 0.2 11.4 15.2 0.11 12.2 1.8 3.7 2 1 2 4 4 4 0 Prefoldin subunit Nnf1 PF03980.9 EKG16254.1 - 0.24 11.4 9.1 0.63 10.0 0.8 2.7 2 0 0 2 2 2 0 Nnf1 Reo_sigmaC PF04582.7 EKG16254.1 - 0.33 10.0 1.8 3.3 6.8 0.2 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IFT57 PF10498.4 EKG16254.1 - 0.5 9.0 15.2 1 8.0 3.7 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 KIAA1430 PF13879.1 EKG16254.1 - 0.58 10.6 13.0 2.1 8.8 3.1 2.5 2 0 0 2 2 2 0 KIAA1430 homologue TMCO5 PF14992.1 EKG16254.1 - 0.79 8.7 10.5 0.39 9.8 0.6 2.1 2 0 0 2 2 2 0 TMCO5 family DUF972 PF06156.8 EKG16254.1 - 1.1 9.6 13.5 0.68 10.3 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EKG16254.1 - 1.3 8.8 20.1 2.8 7.7 2.0 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Troponin PF00992.15 EKG16254.1 - 1.3 9.0 13.8 2.6 8.1 4.3 2.3 2 0 0 2 2 2 0 Troponin HALZ PF02183.13 EKG16254.1 - 2.2 8.0 8.4 2.4 7.9 0.2 3.3 2 2 1 3 3 3 0 Homeobox associated leucine zipper Atg14 PF10186.4 EKG16254.1 - 2.2 7.1 17.6 3.1 6.6 4.0 2.6 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EKG16254.1 - 2.3 7.7 21.9 4.2 6.9 2.5 2.2 2 0 0 2 2 2 0 IncA protein TBPIP PF07106.8 EKG16254.1 - 3 7.3 11.3 6.1 6.3 0.8 2.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Endonuc_Holl PF10107.4 EKG16254.1 - 3.5 7.2 8.4 0.76 9.4 0.3 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DivIC PF04977.10 EKG16254.1 - 4 6.9 17.3 0.29 10.6 1.2 3.6 2 1 1 3 3 3 0 Septum formation initiator ADIP PF11559.3 EKG16254.1 - 4 7.3 26.9 1.2 9.0 7.0 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding P4Ha_N PF08336.6 EKG16254.1 - 4.2 7.2 9.3 3.3 7.5 1.3 3.1 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Phage_GPO PF05929.6 EKG16254.1 - 4.8 6.3 8.2 13 4.9 0.2 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TMF_DNA_bd PF12329.3 EKG16254.1 - 4.9 7.0 17.5 1.7 8.5 1.9 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 EKG16254.1 - 5.5 7.0 27.9 0.25 11.3 2.3 3.0 2 1 1 3 3 3 0 Flagellar FliJ protein MFS_1 PF07690.11 EKG16255.1 - 6.4e-15 54.7 25.8 9.3e-15 54.1 11.8 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Methyltransf_23 PF13489.1 EKG16256.1 - 0.00055 19.6 0.0 0.0028 17.3 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG16256.1 - 0.03 14.7 0.0 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.17 EKG16257.1 - 4e-19 68.4 0.0 5.1e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EKG16258.1 - 2e-31 109.3 0.0 2.2e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NmrA PF05368.8 EKG16260.1 - 1.6e-15 57.0 0.0 1.9e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG16260.1 - 1.9e-14 54.0 0.0 4.1e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG16260.1 - 1.1e-05 25.0 0.1 4.7e-05 22.9 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EKG16260.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2490 PF10677.4 EKG16263.1 - 0.014 14.7 0.1 0.016 14.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2490) Ceramidase PF05875.7 EKG16265.1 - 0.0082 15.3 4.0 0.032 13.3 0.2 2.2 2 0 0 2 2 2 1 Ceramidase DUF2298 PF10060.4 EKG16265.1 - 0.025 13.4 7.8 0.028 13.2 5.4 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) DUF63 PF01889.12 EKG16265.1 - 0.027 14.5 7.5 0.053 13.5 1.3 2.1 1 1 1 2 2 2 0 Membrane protein of unknown function DUF63 O-antigen_lig PF13425.1 EKG16265.1 - 2.7 7.9 10.7 1.2 9.1 2.1 2.1 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Wzy_C PF04932.10 EKG16265.1 - 5.9 6.6 9.0 2.8 7.7 2.2 2.1 2 0 0 2 2 2 0 O-Antigen ligase p450 PF00067.17 EKG16266.1 - 1e-22 80.3 0.0 1.3e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EKG16269.1 - 2.4e-28 98.7 0.0 5.7e-28 97.5 0.0 1.5 1 1 0 1 1 1 1 Transferase family adh_short PF00106.20 EKG16270.1 - 5.7e-12 45.8 2.0 9.7e-12 45.1 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG16270.1 - 2.2e-06 27.4 0.2 6.2e-06 25.9 0.1 1.7 2 0 0 2 2 2 1 KR domain Amidohydro_2 PF04909.9 EKG16270.1 - 0.059 12.9 0.1 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase MARVEL PF01284.18 EKG16271.1 - 1.5e-05 24.8 15.3 2.1e-05 24.3 10.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2415 PF10313.4 EKG16273.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Beta-lactamase PF00144.19 EKG16274.1 - 2.2e-62 211.0 0.1 2.6e-62 210.7 0.1 1.0 1 0 0 1 1 1 1 Beta-lactamase Citrate_ly_lig PF08218.6 EKG16276.1 - 0.023 14.1 0.1 1.7 8.1 0.0 2.1 1 1 1 2 2 2 0 Citrate lyase ligase C-terminal domain HMG_CoA_synt_C PF08540.5 EKG16277.1 - 4.3e-101 338.1 0.9 5.2e-101 337.8 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EKG16277.1 - 6.4e-62 208.1 0.3 1.4e-39 135.4 0.2 2.3 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3197 PF11432.3 EKG16277.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Terpene_synth_C PF03936.11 EKG16278.1 - 3.9e-08 32.8 0.1 5.4e-08 32.3 0.1 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF4367 PF14285.1 EKG16278.1 - 0.044 13.0 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DUF464 PF04327.7 EKG16278.1 - 0.063 13.5 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF464) p450 PF00067.17 EKG16279.1 - 7.4e-28 97.2 0.0 1.7e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF4540 PF15073.1 EKG16279.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4540) MFS_1 PF07690.11 EKG16280.1 - 3.3e-05 22.7 1.4 4e-05 22.4 1.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SecE PF00584.15 EKG16280.1 - 0.21 11.1 5.1 0.35 10.4 3.6 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Sugar_tr PF00083.19 EKG16281.1 - 5e-05 22.0 4.5 5e-05 22.0 3.1 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EKG16281.1 - 0.01 14.0 5.2 0.01 14.0 3.6 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Adeno_E3_CR2 PF02439.10 EKG16281.1 - 0.11 12.0 1.0 0.48 10.0 0.7 2.0 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TatC PF00902.13 EKG16281.1 - 0.78 9.1 11.0 4 6.7 7.5 2.2 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Peptidase_M50 PF02163.17 EKG16281.1 - 1.4 7.8 5.5 0.16 10.8 0.5 1.9 2 0 0 2 2 2 0 Peptidase family M50 PAT1 PF09770.4 EKG16282.1 - 5.1 5.2 14.9 6.4 4.8 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RVP PF00077.15 EKG16283.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease FAD_binding_3 PF01494.14 EKG16284.1 - 1.4e-12 47.3 0.0 1e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EKG16284.1 - 0.072 11.9 0.0 0.28 9.9 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Glyco_hydro_71 PF03659.9 EKG16285.1 - 1e-30 106.5 2.7 1.2e-30 106.2 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 adh_short_C2 PF13561.1 EKG16288.1 - 3.4e-07 30.2 0.1 3.4e-07 30.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG16288.1 - 0.00041 20.3 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase AMP-binding PF00501.23 EKG16289.1 - 1.9e-93 313.1 0.0 3.8e-93 312.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EKG16289.1 - 6.3e-24 84.3 0.0 3.6e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EKG16289.1 - 1.6e-08 34.6 0.0 4.5e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG16289.1 - 2.5e-06 28.3 0.1 8.5e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EKG16290.1 - 1e-26 93.5 76.9 1.6e-23 82.9 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EKG16291.1 - 0.00015 21.3 0.1 0.00082 18.9 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG16291.1 - 0.001 19.9 0.1 0.0024 18.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG16291.1 - 0.054 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.20 EKG16295.1 - 3.6e-11 43.2 0.1 4.2e-11 43.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG16295.1 - 1.9e-05 24.3 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG16295.1 - 0.0046 16.7 0.0 0.0051 16.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG16295.1 - 0.02 14.3 0.0 0.022 14.1 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EKG16296.1 - 0.0094 15.2 0.0 0.011 15.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family Peptidase_M20 PF01546.23 EKG16297.1 - 2.3e-20 72.9 0.0 3.2e-19 69.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EKG16297.1 - 6.6e-17 60.6 0.3 3.2e-06 26.8 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.9 EKG16297.1 - 3.6e-08 33.1 0.0 7.4e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.1 EKG16297.1 - 0.0036 17.5 3.3 33 4.9 0.0 5.1 4 0 0 4 4 4 0 PQQ-like domain Erf4 PF10256.4 EKG16297.1 - 0.021 14.7 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DNA_pol_viral_N PF00242.12 EKG16298.1 - 0.66 8.9 12.8 0.43 9.5 1.3 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Adeno_PIX PF03955.9 EKG16298.1 - 6.8 7.2 6.1 1.3 9.5 0.1 2.5 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Tim17 PF02466.14 EKG16299.1 - 7.3e-33 113.3 7.2 8.4e-33 113.1 5.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BTB PF00651.26 EKG16300.1 - 5e-06 26.4 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain COX15-CtaA PF02628.10 EKG16301.1 - 1.9e-74 250.3 9.8 2.2e-74 250.0 6.8 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3142 PF11340.3 EKG16301.1 - 0.082 12.5 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF1689 PF07954.6 EKG16301.1 - 4.8 7.0 5.5 48 3.7 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1689) Peptidase_S15 PF02129.13 EKG16302.1 - 3.7e-24 85.5 6.6 4.7e-23 81.9 1.1 2.6 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EKG16302.1 - 1.9e-23 83.5 0.6 2.5e-23 83.1 0.4 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hemocyanin_N PF03722.9 EKG16302.1 - 0.042 13.9 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Hemocyanin, all-alpha domain Peptidase_M26_N PF05342.9 EKG16302.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region UPF0086 PF01868.11 EKG16303.1 - 5.2e-26 90.1 0.1 8e-26 89.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 HET PF06985.6 EKG16304.1 - 2.6e-23 82.7 0.0 4.9e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GMC_oxred_C PF05199.8 EKG16305.1 - 1.9e-28 99.5 0.0 3.5e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EKG16305.1 - 2.9e-24 85.7 0.0 1.1e-17 64.1 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase Pyr_redox_2 PF07992.9 EKG16305.1 - 5.5e-05 23.1 0.0 0.0002 21.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG16305.1 - 0.00014 20.9 0.0 0.01 14.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG16305.1 - 0.00062 19.7 0.2 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG16305.1 - 0.0013 17.6 0.0 0.029 13.2 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EKG16305.1 - 0.0091 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EKG16305.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EKG16305.1 - 0.11 12.5 0.0 18 5.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF378 PF04070.7 EKG16306.1 - 0.048 13.2 0.1 0.12 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF378) TRAP-gamma PF07074.7 EKG16306.1 - 0.073 12.5 2.6 0.17 11.3 1.8 1.5 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Peroxidase_2 PF01328.12 EKG16307.1 - 3e-14 52.4 0.1 2.5e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Peroxidase, family 2 DUF1501 PF07394.7 EKG16310.1 - 0.12 11.2 6.0 0.17 10.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Nucleo_P87 PF07267.6 EKG16310.1 - 7 5.1 10.9 11 4.5 7.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PhyH PF05721.8 EKG16311.1 - 1.4e-20 74.2 0.0 1.7e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) eIF3g PF12353.3 EKG16312.1 - 0.017 15.0 4.8 0.032 14.1 3.3 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Asp_protease_2 PF13650.1 EKG16314.1 - 1.3e-08 35.2 0.0 3.3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EKG16314.1 - 3.7e-05 23.4 0.0 9.8e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EKG16314.1 - 0.003 17.4 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 EKG16314.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease DAO PF01266.19 EKG16315.1 - 0.00014 20.9 0.2 0.0002 20.4 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG16315.1 - 0.0015 18.5 0.4 0.0027 17.6 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EKG16315.1 - 0.026 13.1 0.8 1.2 7.6 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EKG16315.1 - 0.031 14.1 0.7 0.047 13.5 0.5 1.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG16315.1 - 0.04 13.6 0.3 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKG16315.1 - 0.059 12.4 2.4 3.4 6.6 0.3 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EKG16315.1 - 0.07 11.5 0.2 0.097 11.1 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EKG16315.1 - 0.099 11.4 1.0 0.12 11.1 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EKG16316.1 - 5.8e-09 35.4 0.4 1.5e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 EKG16316.1 - 5.6e-05 22.1 0.0 8.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase bZIP_1 PF00170.16 EKG16317.1 - 1.5e-08 34.4 13.1 3.1e-08 33.4 9.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EKG16317.1 - 0.00014 22.1 9.7 0.00024 21.3 6.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EKG16317.1 - 0.0033 17.2 16.6 0.0057 16.4 11.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper SR-25 PF10500.4 EKG16317.1 - 0.031 13.7 1.9 0.039 13.4 1.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_UL6 PF01763.11 EKG16317.1 - 0.032 12.4 0.3 0.032 12.4 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like PAP1 PF08601.5 EKG16317.1 - 0.034 13.8 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Transcription factor PAP1 DnaI_N PF07319.6 EKG16317.1 - 0.062 13.5 0.6 0.11 12.7 0.4 1.4 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus Borrelia_REV PF03978.8 EKG16317.1 - 0.066 12.9 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein V_ATPase_I PF01496.14 EKG16317.1 - 0.08 10.7 0.4 0.071 10.9 0.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EKG16317.1 - 0.37 10.2 3.6 0.38 10.2 1.5 1.7 1 1 0 1 1 1 0 Septum formation initiator LCD1 PF09798.4 EKG16317.1 - 0.83 7.5 3.5 1 7.2 2.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein EAP30 PF04157.11 EKG16317.1 - 4 6.5 7.7 1.3 8.0 3.6 1.5 2 0 0 2 2 2 0 EAP30/Vps36 family GvpL_GvpF PF06386.6 EKG16317.1 - 10 5.6 8.8 2.5 7.6 0.1 2.2 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF PqqD PF05402.7 EKG16318.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) DUF3328 PF11807.3 EKG16321.1 - 1.6e-40 139.1 0.1 1.9e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EKG16322.1 - 1.3e-30 106.7 2.0 1.8e-30 106.2 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EKG16323.1 - 3.7e-20 72.5 0.0 5e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Gpi16 PF04113.9 EKG16324.1 - 2.5e-179 596.9 0.0 3.4e-179 596.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 EKG16325.1 - 1.9e-71 240.5 1.3 2.4e-71 240.2 0.9 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DUF2225 PF09986.4 EKG16325.1 - 0.043 13.2 0.2 0.11 11.9 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3073 PF11273.3 EKG16325.1 - 0.052 14.0 1.4 1.1 9.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3073) PBP_GOBP PF01395.17 EKG16325.1 - 0.11 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 PBP/GOBP family ArfGap PF01412.13 EKG16326.1 - 4e-41 139.4 0.9 6.1e-41 138.8 0.6 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SNARE PF05739.14 EKG16327.1 - 0.0057 16.3 0.1 0.0084 15.7 0.1 1.3 1 0 0 1 1 1 1 SNARE domain DUF4349 PF14257.1 EKG16327.1 - 0.071 12.3 0.1 0.087 12.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Synaptobrevin PF00957.16 EKG16327.1 - 0.1 12.1 2.5 0.7 9.5 1.0 2.0 1 1 1 2 2 2 0 Synaptobrevin SLAC1 PF03595.12 EKG16328.1 - 4.7e-33 114.2 16.4 5.6e-33 113.9 11.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RelA_SpoT PF04607.12 EKG16329.1 - 9.3e-14 51.4 1.5 8.1e-13 48.3 1.0 2.4 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins CorA PF01544.13 EKG16330.1 - 4.6e-07 29.1 0.2 1.4e-06 27.5 0.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Mucin PF01456.12 EKG16333.1 - 0.0058 16.4 4.7 0.0092 15.7 3.3 1.4 1 1 0 1 1 1 1 Mucin-like glycoprotein Abhydrolase_3 PF07859.8 EKG16334.1 - 1.5e-39 135.7 0.0 3.5e-31 108.4 0.1 3.2 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EKG16334.1 - 1.3e-09 37.2 0.0 2.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EKG16334.1 - 0.00035 20.3 0.1 0.0011 18.7 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 EKG16334.1 - 0.0014 17.4 0.1 0.052 12.2 0.0 2.2 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EKG16334.1 - 0.0021 17.9 0.0 0.006 16.4 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family WGG PF10273.4 EKG16335.1 - 0.0032 17.5 0.6 0.0067 16.4 0.4 1.6 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 EKG16335.1 - 0.052 13.5 0.7 0.092 12.7 0.3 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) RXT2_N PF08595.6 EKG16335.1 - 0.34 10.7 2.5 0.37 10.5 1.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 EKG16335.1 - 0.37 10.3 4.9 0.4 10.2 3.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EKG16335.1 - 0.63 8.7 10.6 0.55 8.8 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 EKG16335.1 - 0.88 8.7 4.7 0.91 8.7 3.2 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EKG16335.1 - 3 7.3 13.8 3.4 7.1 9.5 1.4 1 1 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EKG16335.1 - 7 4.4 11.3 7.3 4.3 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family BSD PF03909.12 EKG16336.1 - 9.1e-16 57.3 0.9 1.6e-15 56.5 0.6 1.4 1 0 0 1 1 1 1 BSD domain RXT2_N PF08595.6 EKG16336.1 - 0.078 12.7 0.5 0.16 11.8 0.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Ran-binding PF05508.6 EKG16337.1 - 8.9e-84 280.9 0.0 1.1e-83 280.5 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.22 EKG16338.1 - 3.3e-44 150.5 0.0 5.6e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKG16338.1 - 2.3e-20 72.6 0.1 1.3e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EKG16338.1 - 0.0003 20.7 0.0 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EKG16338.1 - 0.0033 17.4 0.2 0.0082 16.2 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 G-alpha PF00503.15 EKG16338.1 - 0.082 11.5 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit APC_CDC26 PF10471.4 EKG16338.1 - 0.43 11.3 0.1 0.43 11.3 0.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 adh_short PF00106.20 EKG16339.1 - 4e-20 72.3 0.4 1e-10 41.7 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EKG16339.1 - 1.1e-07 31.7 0.1 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EKG16339.1 - 0.00079 19.2 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Peripla_BP_4 PF13407.1 EKG16339.1 - 0.0015 17.9 0.2 0.39 10.0 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein domain NAD_binding_10 PF13460.1 EKG16339.1 - 0.0079 16.2 4.6 0.45 10.4 1.8 3.3 2 1 1 3 3 3 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG16339.1 - 0.036 12.7 0.5 0.054 12.1 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2931 PF11153.3 EKG16340.1 - 0.12 11.7 0.1 0.14 11.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2931) Ins_allergen_rp PF06757.8 EKG16342.1 - 0.033 13.6 0.1 1.1 8.7 0.0 2.0 1 1 1 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Pyr_redox_3 PF13738.1 EKG16343.1 - 3.7e-28 98.9 0.1 9.4e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG16343.1 - 9.3e-07 28.7 2.8 1.5e-06 28.0 0.5 2.6 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG16343.1 - 9.7e-06 25.5 0.0 0.00014 21.7 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG16343.1 - 1.6e-05 25.0 0.1 0.014 15.5 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EKG16343.1 - 4.1e-05 23.4 0.1 0.012 15.4 0.1 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EKG16343.1 - 0.0045 15.8 0.4 0.0099 14.7 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EKG16343.1 - 0.0049 16.0 0.0 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EKG16343.1 - 0.08 11.7 0.5 0.31 9.8 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 EKG16343.1 - 0.094 10.8 0.7 0.19 9.8 0.0 1.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 EKG16343.1 - 0.2 10.6 1.8 0.34 9.9 0.6 1.8 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 EKG16343.1 - 3 7.6 4.6 1.2 8.8 0.5 2.2 3 0 0 3 3 3 0 ThiF family DAO PF01266.19 EKG16343.1 - 3.2 6.5 9.1 1.1 8.1 3.6 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase Tautomerase_3 PF14832.1 EKG16344.1 - 2.1e-52 176.7 0.0 2.4e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme adh_short PF00106.20 EKG16345.1 - 1.1e-33 116.4 1.6 1.8e-33 115.8 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG16345.1 - 3.3e-30 105.6 1.5 4.1e-30 105.3 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG16345.1 - 2.5e-15 56.5 0.6 3.6e-15 56.0 0.4 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EKG16345.1 - 0.0029 16.7 0.0 0.0085 15.2 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GIDA PF01134.17 EKG16345.1 - 0.0038 16.1 2.0 0.0047 15.8 1.4 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Eno-Rase_NADH_b PF12242.3 EKG16345.1 - 0.018 14.8 0.6 0.046 13.5 0.4 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG16345.1 - 0.022 14.2 0.6 0.083 12.3 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sipho_tail PF05709.6 EKG16345.1 - 0.046 12.8 0.1 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein 3HCDH_N PF02737.13 EKG16345.1 - 0.12 12.0 0.9 0.53 9.9 0.2 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tautomerase_3 PF14832.1 EKG16346.1 - 1.7e-45 154.3 0.1 2e-45 154.1 0.1 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EKG16346.1 - 0.055 13.0 0.1 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Tautomerase enzyme NmrA PF05368.8 EKG16348.1 - 2.7e-25 88.9 0.0 3.8e-19 68.8 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EKG16348.1 - 0.19 11.7 1.2 0.62 10.0 0.8 1.8 1 1 0 1 1 1 0 NADH(P)-binding ABC2_membrane PF01061.19 EKG16349.1 - 1.7e-88 295.2 38.4 6.9e-45 152.8 12.3 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EKG16349.1 - 3.6e-38 130.9 0.0 9.5e-19 68.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG16349.1 - 2.5e-28 97.7 2.9 1.1e-24 86.0 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EKG16349.1 - 2.5e-16 59.6 20.1 1.5e-09 37.3 4.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EKG16349.1 - 1.5e-06 28.1 0.0 3.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EKG16349.1 - 1.3e-05 24.6 0.1 0.014 14.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKG16349.1 - 7e-05 22.9 0.1 0.046 13.8 0.0 3.4 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 EKG16349.1 - 0.0002 20.6 0.0 0.0059 15.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EKG16349.1 - 0.0011 18.4 1.0 0.32 10.4 0.2 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EKG16349.1 - 0.0028 17.1 0.5 0.078 12.5 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 EKG16349.1 - 0.004 16.6 0.6 1.3 8.4 0.1 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EKG16349.1 - 0.0052 16.8 0.3 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EKG16349.1 - 0.0091 15.9 1.4 0.22 11.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG16349.1 - 0.024 15.4 0.0 1.5 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EKG16349.1 - 0.061 13.6 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EKG16349.1 - 0.1 12.2 0.5 2.4 7.7 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EKG16349.1 - 0.11 12.3 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EKG16349.1 - 0.12 12.1 1.0 22 4.8 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain Arf PF00025.16 EKG16349.1 - 0.16 11.2 0.1 6.9 5.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKG16349.1 - 0.17 11.8 0.0 26 4.8 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EKG16349.1 - 0.24 11.1 0.0 0.6 9.9 0.0 1.6 1 0 0 1 1 1 0 Dynamin family MFS_2 PF13347.1 EKG16350.1 - 0.00053 18.5 23.8 0.00053 18.5 16.5 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EKG16350.1 - 0.14 11.9 5.0 0.21 11.3 0.0 3.3 3 1 0 3 3 3 0 MFS_1 like family adh_short PF00106.20 EKG16351.1 - 6.8e-20 71.6 0.4 9.5e-20 71.1 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG16351.1 - 8.9e-08 32.0 0.1 1.1e-07 31.7 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG16351.1 - 1.2e-05 25.1 0.1 1.6e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG16351.1 - 0.00015 21.2 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG16351.1 - 0.083 12.6 0.4 0.18 11.6 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1485 PF07364.7 EKG16351.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1485) p450 PF00067.17 EKG16352.1 - 5.3e-46 157.0 0.0 8e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FlgM PF04316.8 EKG16352.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM Abhydrolase_6 PF12697.2 EKG16353.1 - 4.1e-17 62.8 0.0 5.3e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG16353.1 - 2.8e-16 59.5 0.0 5.2e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EKG16353.1 - 1.3e-06 28.0 0.0 1.8e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EKG16353.1 - 2.7e-06 26.7 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 EKG16353.1 - 4.4e-06 25.4 0.0 0.0054 15.2 0.0 2.5 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EKG16353.1 - 2.4e-05 24.1 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EKG16353.1 - 0.0065 15.7 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EKG16353.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase ketoacyl-synt PF00109.21 EKG16354.1 - 1.2e-22 80.6 0.0 1.3e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain GBP_repeat PF02526.9 EKG16354.1 - 0.12 11.7 0.0 0.67 9.3 0.0 2.1 2 0 0 2 2 2 0 Glycophorin-binding protein Acyl_transf_1 PF00698.16 EKG16355.1 - 1.4e-54 185.6 0.0 3.1e-54 184.4 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EKG16355.1 - 9.2e-54 181.8 0.8 7.2e-53 178.9 0.4 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EKG16355.1 - 2.8e-48 164.6 1.0 1e-47 162.7 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 EKG16355.1 - 1.5e-39 135.6 0.7 1.5e-39 135.6 0.5 3.5 4 0 0 4 4 4 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG16355.1 - 9.8e-37 125.4 4.5 2.6e-35 120.8 0.3 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EKG16355.1 - 1.1e-19 70.2 0.0 9.2e-19 67.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG16355.1 - 4.3e-14 53.4 0.0 7.6e-13 49.4 0.0 3.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EKG16355.1 - 2.4e-07 30.9 0.0 9e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 EKG16355.1 - 3.3e-06 26.8 0.0 7.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 EKG16355.1 - 0.00018 21.0 0.0 0.00018 21.0 0.0 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Beta-lactamase PF00144.19 EKG16357.1 - 7.9e-20 71.1 0.0 8.8e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF3176 PF11374.3 EKG16358.1 - 2e-39 133.9 1.0 5.8e-39 132.4 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF1772 PF08592.6 EKG16359.1 - 7.1e-14 51.7 4.1 7.1e-14 51.7 2.8 1.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) Glyco_hydro_71 PF03659.9 EKG16360.1 - 2.6e-80 269.7 3.7 3.4e-80 269.3 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.1 EKG16360.1 - 0.021 14.0 0.4 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase WbsX Peptidase_S9 PF00326.16 EKG16361.1 - 2.3e-06 26.9 0.1 4.5e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EKG16361.1 - 5.1e-06 26.5 0.5 7e-05 22.8 0.1 2.0 1 1 2 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG16361.1 - 5.5e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EKG16361.1 - 5.7e-06 26.1 0.1 1.6e-05 24.6 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EKG16361.1 - 0.00017 20.8 0.2 0.00034 19.9 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EKG16361.1 - 0.00082 18.9 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EKG16361.1 - 0.0014 18.1 0.2 0.0024 17.3 0.1 1.5 1 1 0 1 1 1 1 Putative esterase p450 PF00067.17 EKG16364.1 - 2.6e-58 197.6 0.0 3.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FSH1 PF03959.8 EKG16365.1 - 1.7e-32 112.5 0.0 6.4e-32 110.7 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EKG16365.1 - 2.3e-06 27.6 0.9 4.8e-06 26.6 0.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG16365.1 - 0.00077 18.9 0.4 1.4 8.2 0.1 2.9 3 1 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EKG16365.1 - 0.033 13.9 0.0 0.065 12.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EKG16366.1 - 2.4e-23 82.4 14.0 2.6e-23 82.3 9.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16366.1 - 7.6e-06 24.7 9.7 1.2e-05 24.1 6.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF805 PF05656.9 EKG16366.1 - 0.0075 16.0 0.7 0.018 14.8 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF805) PUCC PF03209.10 EKG16366.1 - 0.042 12.5 3.0 0.046 12.4 2.1 1.2 1 0 0 1 1 1 0 PUCC protein FAD_binding_4 PF01565.18 EKG16367.1 - 1e-17 63.9 2.2 1.9e-17 63.0 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG16367.1 - 3e-11 43.0 0.5 8e-11 41.6 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF2367 PF10164.4 EKG16368.1 - 0.027 14.3 0.3 0.071 12.9 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) DUF863 PF05904.6 EKG16370.1 - 0.016 13.5 0.5 0.016 13.5 0.3 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) S19 PF06756.6 EKG16370.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Chorion protein S19 C-terminal Tnp_DNA_bind PF14706.1 EKG16370.1 - 0.15 11.7 0.4 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 Transposase DNA-binding OPT PF03169.10 EKG16371.1 - 7e-139 464.0 13.5 8e-139 463.9 9.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4212 PF13937.1 EKG16371.1 - 0.03 14.3 8.0 0.9 9.5 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4212) Hemerythrin PF01814.18 EKG16372.1 - 4.6e-06 26.8 1.2 5.5e-06 26.5 0.4 1.5 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain MFS_1 PF07690.11 EKG16374.1 - 2.4e-24 85.7 46.6 2.4e-24 85.7 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DIT1_PvcA PF05141.7 EKG16375.1 - 5.6e-72 242.3 0.0 6.5e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DIT1_PvcA PF05141.7 EKG16376.1 - 1.3e-23 83.7 0.0 2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein MoaF PF10703.4 EKG16377.1 - 0.098 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F BNR PF02012.15 EKG16377.1 - 4.8 7.4 8.0 10 6.4 1.5 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat ADH_N PF08240.7 EKG16378.1 - 4.8e-25 87.4 2.1 7.4e-25 86.8 1.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG16378.1 - 1.5e-20 73.0 0.0 2.9e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG16378.1 - 1.6e-06 29.0 0.0 2.6e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG16378.1 - 0.00052 19.2 0.1 0.00089 18.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EKG16378.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EKG16379.1 - 7.1e-15 54.8 0.1 9.5e-15 54.4 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family DUF1275 PF06912.6 EKG16381.1 - 3e-42 144.2 14.1 3.9e-42 143.8 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Sugar_tr PF00083.19 EKG16385.1 - 6.2e-92 308.5 23.3 7e-92 308.3 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG16385.1 - 2.4e-21 75.8 47.6 3e-20 72.2 15.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG16385.1 - 0.0005 18.3 0.4 0.0005 18.3 0.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG16388.1 - 7.9e-34 116.9 88.5 2.8e-31 108.5 36.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily SRP54_N PF02881.14 EKG16389.1 - 0.05 13.7 0.1 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain RRM_6 PF14259.1 EKG16390.1 - 9.4e-14 51.1 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG16390.1 - 1.6e-13 50.0 0.1 3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG16390.1 - 6.8e-07 29.0 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G0-G1_switch_2 PF15103.1 EKG16390.1 - 1.5 9.0 3.8 3.5 7.8 2.7 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 Hamartin PF04388.7 EKG16390.1 - 2.6 6.6 13.2 3.4 6.2 9.2 1.1 1 0 0 1 1 1 0 Hamartin protein Borrelia_P83 PF05262.6 EKG16390.1 - 7.3 4.7 13.1 12 4.0 9.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DOT1 PF08123.8 EKG16391.1 - 4e-67 225.5 0.0 5.2e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 EKG16391.1 - 0.028 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Trp_halogenase PF04820.9 EKG16394.1 - 2.2e-11 43.1 0.2 0.0003 19.5 0.1 3.1 3 0 0 3 3 3 3 Tryptophan halogenase DAO PF01266.19 EKG16394.1 - 0.0067 15.3 3.3 0.05 12.5 1.0 2.5 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG16394.1 - 0.064 13.2 0.6 0.19 11.7 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG16394.1 - 0.11 12.9 0.1 22 5.5 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GTP_EFTU PF00009.22 EKG16395.1 - 5.7e-60 201.9 0.4 7.7e-60 201.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKG16395.1 - 7.6e-26 90.1 0.1 4.5e-25 87.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKG16395.1 - 1.6e-18 66.5 2.1 2.6e-18 65.9 0.9 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKG16395.1 - 2.5e-06 27.4 0.1 4.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EKG16395.1 - 0.0003 20.3 0.2 0.00098 18.7 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EKG16395.1 - 0.0004 20.8 0.0 0.00071 20.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EKG16395.1 - 0.013 15.0 0.5 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EKG16395.1 - 0.12 11.8 1.0 0.43 9.9 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ECH_C PF13766.1 EKG16396.1 - 4.8e-33 113.7 0.1 9.8e-33 112.8 0.1 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EKG16396.1 - 5.5e-28 97.7 0.0 8.5e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Mito_carr PF00153.22 EKG16398.1 - 8.9e-58 192.0 2.7 6.3e-20 70.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF787 PF05619.6 EKG16398.1 - 0.027 13.1 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Methyltransf_26 PF13659.1 EKG16398.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EKG16399.1 - 4e-16 58.2 2.6 4.2e-11 42.2 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EKG16399.1 - 0.041 12.6 0.1 4 6.0 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like STAG PF08514.6 EKG16399.1 - 0.042 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 STAG domain DUF4613 PF15390.1 EKG16399.1 - 0.11 10.6 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) TRAPP PF04051.11 EKG16400.1 - 2.1e-32 111.7 0.0 2.8e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component HET PF06985.6 EKG16401.1 - 1.4e-23 83.5 0.0 2.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Acetyltransf_1 PF00583.19 EKG16402.1 - 4e-07 29.9 0.1 5.7e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG16402.1 - 0.0015 18.6 0.0 0.0021 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG16402.1 - 0.0034 17.5 0.0 0.0054 16.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKG16402.1 - 0.0038 17.0 0.0 0.0045 16.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG16402.1 - 0.0069 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EKG16402.1 - 0.019 15.0 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Med3 PF11593.3 EKG16403.1 - 1.3 8.1 4.7 1.8 7.7 3.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Transferase PF02458.10 EKG16404.1 - 2.3e-22 79.0 0.0 2.8e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Transferase family Sulfatase PF00884.18 EKG16405.1 - 4.2e-64 216.6 0.1 5.5e-64 216.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase GFA PF04828.9 EKG16406.1 - 1.3e-17 63.4 0.0 2.2e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DHDPS PF00701.17 EKG16407.1 - 8.8e-22 77.0 0.0 9.8e-22 76.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FMN_dh PF01070.13 EKG16408.1 - 5.1e-15 55.1 0.0 6.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Fungal_trans_2 PF11951.3 EKG16410.1 - 9.2e-45 152.8 1.3 1.1e-44 152.5 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain XFP_N PF09364.5 EKG16411.1 - 1.5e-180 599.7 0.0 2e-180 599.3 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EKG16411.1 - 7.5e-89 296.5 0.0 1.1e-88 295.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EKG16411.1 - 1.1e-82 275.9 0.0 2.5e-82 274.7 0.0 1.6 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Alb1 PF09135.6 EKG16412.1 - 6.9e-17 62.0 15.9 1e-16 61.5 11.0 1.3 1 0 0 1 1 1 1 Alb1 V_ATPase_I PF01496.14 EKG16412.1 - 0.51 8.1 1.7 0.51 8.1 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.1 EKG16412.1 - 1.5 9.0 6.4 1.7 8.9 4.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4315 PF14193.1 EKG16412.1 - 1.6 8.7 8.3 0.14 12.0 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4315) F-protein PF00469.15 EKG16412.1 - 1.8 7.9 10.3 0.2 11.0 4.4 1.4 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Atg14 PF10186.4 EKG16412.1 - 3.9 6.3 9.5 4.5 6.1 6.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Uds1 PF15456.1 EKG16412.1 - 9.5 6.2 11.5 19 5.2 7.9 1.6 1 1 0 1 1 1 0 Up-regulated During Septation UCH PF00443.24 EKG16413.1 - 3e-36 124.9 0.0 7.3e-36 123.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG16413.1 - 2.7e-10 40.1 0.0 9.5e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_11 PF13414.1 EKG16415.1 - 1.7e-46 155.7 39.7 3.7e-10 39.3 0.1 13.3 13 3 2 15 15 13 9 TPR repeat TPR_16 PF13432.1 EKG16415.1 - 1e-31 108.8 56.4 1.6e-09 38.1 5.7 13.6 11 3 3 15 15 15 7 Tetratricopeptide repeat TPR_1 PF00515.23 EKG16415.1 - 5.1e-31 105.0 32.0 4.4e-05 22.9 0.0 16.0 18 0 0 18 18 17 7 Tetratricopeptide repeat TPR_17 PF13431.1 EKG16415.1 - 4.1e-30 101.4 10.0 0.0035 17.4 0.0 16.2 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_2 PF07719.12 EKG16415.1 - 1e-29 100.0 50.6 0.00035 20.2 0.0 18.8 20 0 0 20 20 19 6 Tetratricopeptide repeat TPR_14 PF13428.1 EKG16415.1 - 1.2e-28 96.9 58.1 3.4e-05 24.0 1.3 17.7 12 6 7 19 19 19 7 Tetratricopeptide repeat TPR_19 PF14559.1 EKG16415.1 - 5e-25 87.6 38.5 5.9e-06 26.5 1.6 13.2 12 2 3 15 15 14 5 Tetratricopeptide repeat TPR_8 PF13181.1 EKG16415.1 - 8.6e-25 84.6 8.6 0.25 11.2 0.0 14.2 13 1 1 14 14 13 5 Tetratricopeptide repeat TPR_12 PF13424.1 EKG16415.1 - 2.3e-18 65.8 45.5 0.002 18.0 0.2 14.8 10 3 7 17 17 16 7 Tetratricopeptide repeat TPR_6 PF13174.1 EKG16415.1 - 1.5e-12 47.0 24.8 2.2 8.9 0.0 15.0 16 0 0 16 16 14 1 Tetratricopeptide repeat Apc3 PF12895.2 EKG16415.1 - 4.3e-11 42.8 17.9 0.015 15.4 0.0 8.8 9 1 1 10 10 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EKG16415.1 - 1.7e-10 39.8 32.7 0.026 14.3 0.1 12.1 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_9 PF13371.1 EKG16415.1 - 7.4e-09 35.3 37.8 0.00031 20.5 0.3 10.1 8 2 2 11 11 11 3 Tetratricopeptide repeat SpoIIE PF07228.7 EKG16415.1 - 0.007 16.0 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF3366 PF11846.3 EKG16415.1 - 0.018 14.9 2.2 1.7 8.4 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) ChAPs PF09295.5 EKG16415.1 - 0.024 13.4 3.0 22 3.6 0.0 4.9 6 0 0 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 EKG16415.1 - 0.088 13.2 0.2 0.088 13.2 0.2 9.3 11 0 0 11 11 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EKG16415.1 - 0.32 10.2 6.4 2.4 7.4 0.7 4.4 4 0 0 4 4 4 0 SHNi-TPR Fusion_gly PF00523.13 EKG16415.1 - 0.36 8.8 0.1 3.2 5.7 0.0 2.0 2 0 0 2 2 2 0 Fusion glycoprotein F0 TPR_10 PF13374.1 EKG16415.1 - 2.9 7.9 25.7 5.2 7.1 0.1 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF2013 PF09431.5 EKG16416.1 - 1.1e-45 154.8 0.7 1.1e-45 154.8 0.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) DnaJ PF00226.26 EKG16417.1 - 5.9e-25 86.7 2.1 5.9e-25 86.7 1.4 2.6 2 1 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 EKG16417.1 - 6.5e-18 63.1 7.1 0.012 15.5 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 EKG16417.1 - 7.5e-18 63.9 10.7 3.7e-08 32.8 0.1 6.0 5 2 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 EKG16417.1 - 2.8e-14 52.0 12.1 0.0004 19.8 0.0 7.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKG16417.1 - 3.6e-14 52.9 2.7 0.00016 22.2 0.2 6.4 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKG16417.1 - 4.7e-11 41.6 6.1 0.0094 15.6 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG16417.1 - 1.5e-10 40.6 9.8 2.2 9.1 0.0 8.2 3 2 6 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EKG16417.1 - 1.4e-08 34.4 0.4 0.12 12.2 0.0 4.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EKG16417.1 - 7.1e-08 32.6 9.2 0.045 14.0 0.1 6.3 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EKG16417.1 - 4e-06 26.9 14.6 1.6 9.3 0.4 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG16417.1 - 2.1e-05 24.3 2.6 1.2 9.5 0.0 5.3 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKG16417.1 - 0.00032 20.5 7.6 0.046 13.6 0.1 5.7 5 3 2 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG16417.1 - 0.00097 18.7 2.3 1.1 9.2 0.1 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat AAA_10 PF12846.2 EKG16417.1 - 4 6.7 5.5 6.6 6.0 2.6 1.9 1 1 0 1 1 1 0 AAA-like domain Cellulase PF00150.13 EKG16418.1 - 9.1e-13 48.0 3.8 1.2e-08 34.5 1.5 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EKG16418.1 - 0.00083 18.5 0.5 0.99 8.4 0.0 2.3 2 0 0 2 2 2 2 Beta-galactosidase Glyco_hydro_35 PF01301.14 EKG16418.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Xpo1 PF08389.7 EKG16419.1 - 2e-11 44.0 1.0 7.3e-06 25.9 0.0 4.6 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 EKG16419.1 - 3e-06 27.0 0.1 0.00011 22.0 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HET PF06985.6 EKG16420.1 - 7e-27 94.2 0.0 5.2e-21 75.2 0.1 2.7 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EKG16420.1 - 1.9e-14 53.7 0.0 4.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG16420.1 - 5.4e-12 45.5 0.0 8e-10 38.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG16420.1 - 8.5e-11 42.0 0.0 5e-08 33.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EKG16420.1 - 1.5e-10 40.3 0.0 6.6e-08 31.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EKG16420.1 - 1.4e-09 37.2 0.0 1.3e-06 28.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Glyco_hydro_47 PF01532.15 EKG16421.1 - 3.5e-178 592.9 0.2 4.2e-178 592.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cpn60_TCP1 PF00118.19 EKG16422.1 - 6.3e-152 506.5 0.4 7.2e-152 506.3 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family OTU PF02338.14 EKG16423.1 - 1.6e-12 48.1 0.0 2.7e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EKG16423.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DIOX_N PF14226.1 EKG16424.1 - 1.2e-25 90.3 0.0 1.9e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG16424.1 - 3.2e-18 65.8 0.0 5.3e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4400 PF14348.1 EKG16425.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Sugar_tr PF00083.19 EKG16426.1 - 1.1e-108 363.7 23.4 1.3e-108 363.4 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG16426.1 - 1.3e-26 93.2 24.9 6.6e-17 61.2 1.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Aa_trans PF01490.13 EKG16428.1 - 1.3e-42 145.7 35.3 1.6e-42 145.4 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EKG16428.1 - 1.5e-07 30.6 18.4 1.5e-07 30.6 12.8 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF1680 PF07944.7 EKG16430.1 - 3.6e-132 441.2 0.0 4.1e-132 441.0 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) FAD_binding_3 PF01494.14 EKG16431.1 - 1.8e-35 122.6 0.1 8.9e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.7 EKG16431.1 - 9.1e-33 113.2 0.0 1.3e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Acyltransferase PF01553.16 EKG16433.1 - 2.1e-09 36.8 0.0 3.6e-08 32.9 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Metallophos PF00149.23 EKG16434.1 - 7e-07 28.8 0.5 4e-06 26.3 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG16434.1 - 0.0018 18.1 0.1 0.0044 16.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain vWA-TerF-like PF10138.4 EKG16436.1 - 4.9e-09 36.3 0.0 7.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.1 EKG16436.1 - 0.00029 20.5 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EKG16436.1 - 0.00055 20.0 0.0 0.0013 18.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EKG16436.1 - 0.067 12.9 0.7 0.24 11.0 0.1 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain PH PF00169.24 EKG16437.1 - 1.5e-29 102.2 0.8 5.4e-15 55.4 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EKG16437.1 - 1.1e-10 41.7 5.2 7.1e-05 23.0 0.2 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EKG16437.1 - 3.8e-10 39.9 3.0 4.6e-05 23.5 0.5 3.9 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EKG16437.1 - 8.2e-07 29.0 0.8 2.7e-06 27.3 0.2 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EKG16437.1 - 0.035 14.0 0.7 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology Phasin PF05597.6 EKG16437.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GTP_EFTU PF00009.22 EKG16438.1 - 4.4e-53 179.5 0.0 1e-52 178.3 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EKG16438.1 - 9e-16 57.5 0.0 2.9e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EKG16438.1 - 2.5e-09 36.8 0.0 5.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EKG16438.1 - 2e-08 34.1 0.0 6.6e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EKG16438.1 - 5.1e-05 22.8 0.0 0.0027 17.2 0.0 2.7 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EKG16438.1 - 0.005 16.7 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Hexokinase_2 PF03727.11 EKG16442.1 - 8.6e-77 257.6 0.0 1.1e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EKG16442.1 - 1.1e-67 227.3 0.0 1.7e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 EKG16442.1 - 0.13 11.5 0.0 0.27 10.5 0.0 1.5 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain AMP-binding PF00501.23 EKG16444.1 - 2e-40 138.4 0.0 2.9e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG16444.1 - 1e-06 29.5 0.1 2.8e-06 28.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DnaJ PF00226.26 EKG16445.1 - 1.5e-17 63.0 0.1 3.3e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF2422 PF10337.4 EKG16446.1 - 1.1e-27 97.0 3.0 1.6e-26 93.1 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EKG16446.1 - 2.8e-14 53.1 14.4 5.2e-14 52.2 10.0 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EKG16446.1 - 4.3e-11 42.8 0.0 8.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EKG16446.1 - 0.001 17.8 9.5 0.0085 14.7 6.6 2.1 1 1 0 1 1 1 1 Aluminium activated malate transporter Ashwin PF15323.1 EKG16448.1 - 0.54 10.2 14.0 0.25 11.2 5.0 2.4 2 0 0 2 2 2 0 Developmental protein B-block_TFIIIC PF04182.7 EKG16449.1 - 2.5e-19 68.8 0.0 2.2e-17 62.6 0.0 3.0 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EKG16449.1 - 0.0081 15.8 0.2 0.19 11.4 0.0 2.8 2 0 0 2 2 2 1 MarR family RNA_pol_Rpc34 PF05158.7 EKG16449.1 - 0.12 11.4 0.0 0.33 10.0 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit IncA PF04156.9 EKG16450.1 - 0.68 9.5 2.8 1.1 8.8 2.0 1.3 1 0 0 1 1 1 0 IncA protein UreD PF01774.12 EKG16452.1 - 6.3e-49 166.2 0.0 8.3e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein HCBP_related PF06594.6 EKG16452.1 - 0.082 12.5 0.4 30 4.3 0.0 3.3 3 0 0 3 3 3 0 Haemolysin-type calcium binding protein related domain STAG PF08514.6 EKG16453.1 - 3.4e-24 84.8 0.0 3.4e-24 84.8 0.0 2.6 3 0 0 3 3 3 1 STAG domain p450 PF00067.17 EKG16454.1 - 4.2e-59 200.3 0.0 5.7e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EKG16455.1 - 9.2e-10 37.8 0.2 2e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG16455.1 - 5.6e-08 32.5 7.9 1.2e-07 31.5 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox PF00070.22 EKG16456.1 - 1.7e-08 34.7 2.8 1.4e-07 31.8 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG16456.1 - 7.7e-08 32.4 0.1 0.0028 17.5 0.3 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EKG16456.1 - 1.2 7.6 3.3 2 6.9 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase MIP PF00230.15 EKG16457.1 - 4.1e-22 78.7 0.2 5.4e-22 78.3 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF2298 PF10060.4 EKG16457.1 - 0.028 13.2 0.3 0.033 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Chitin_bind_1 PF00187.14 EKG16458.1 - 8.2e-05 22.5 24.0 0.0004 20.2 12.3 3.4 2 1 1 3 3 3 3 Chitin recognition protein Peptidase_S41 PF03572.13 EKG16459.1 - 1.7e-07 30.8 0.0 6.7e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase family S41 Zeta_toxin PF06414.7 EKG16459.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Herpes_capsid PF06112.6 EKG16459.1 - 3.2 7.7 7.2 0.35 10.9 1.3 2.0 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PCDO_beta_N PF12391.3 EKG16460.1 - 0.021 14.2 0.4 0.059 12.8 0.3 1.7 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Ldl_recept_b PF00058.12 EKG16461.1 - 2.6e-12 46.8 4.1 0.0016 18.7 0.1 5.8 5 1 0 5 5 5 3 Low-density lipoprotein receptor repeat class B SGL PF08450.7 EKG16461.1 - 0.0005 19.5 0.1 0.47 9.7 0.0 2.9 2 2 1 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EKG16461.1 - 0.1 12.5 0.0 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Arylesterase CytochromB561_N PF09786.4 EKG16462.1 - 0.8 8.0 8.2 0.74 8.1 5.7 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Asp PF00026.18 EKG16463.1 - 7.8e-57 192.9 10.1 5.5e-56 190.1 7.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG16463.1 - 7.9e-07 29.5 1.8 1 9.9 0.0 3.6 2 1 0 3 3 3 3 Aspartyl protease Abhydrolase_5 PF12695.2 EKG16464.1 - 1.1e-10 41.4 0.5 1.7e-10 40.8 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EKG16464.1 - 8.5e-09 34.1 0.1 7.9e-06 24.3 0.0 2.5 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EKG16464.1 - 2e-08 34.4 3.0 3.3e-08 33.6 2.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EKG16464.1 - 1.4e-06 27.4 0.0 2.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EKG16464.1 - 0.016 14.0 0.1 2 7.1 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Acyl_transf_1 PF00698.16 EKG16464.1 - 0.02 14.2 3.5 0.042 13.1 2.3 1.5 1 1 0 1 1 1 0 Acyl transferase domain Hydrolase_4 PF12146.3 EKG16464.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF2305 PF10230.4 EKG16466.1 - 6e-17 61.9 0.0 7.6e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EKG16466.1 - 0.00012 21.8 0.1 0.00015 21.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG16466.1 - 0.00012 22.0 0.1 0.00013 21.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EKG16466.1 - 0.011 15.2 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 EKG16468.1 - 3.5e-15 55.9 4.5 1e-09 37.9 0.3 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EKG16468.1 - 1.5e-09 37.2 3.7 5.4e-07 28.8 2.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG16468.1 - 5.7e-09 35.3 0.7 2.6e-08 33.1 0.5 1.9 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EKG16468.1 - 1.5e-07 30.2 0.6 0.00077 18.0 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EKG16468.1 - 4.2e-07 30.0 0.2 4.3e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG16468.1 - 9e-06 25.8 0.2 2.2e-05 24.6 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG16468.1 - 2.4e-05 24.2 0.1 6.7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EKG16468.1 - 3.3e-05 23.1 1.5 0.00033 19.8 0.4 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EKG16468.1 - 0.00012 21.0 0.4 0.0057 15.5 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EKG16468.1 - 0.00015 21.3 0.1 0.0025 17.4 0.0 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EKG16468.1 - 0.0031 17.8 0.3 0.057 13.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG16468.1 - 0.0042 16.0 1.1 1.7 7.4 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EKG16468.1 - 0.0079 15.3 0.1 0.017 14.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 EKG16468.1 - 0.045 13.4 0.1 0.13 11.9 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EKG16468.1 - 0.058 12.4 0.9 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EKG16468.1 - 0.084 11.4 1.1 3.3 6.2 0.1 2.7 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EKG16468.1 - 0.36 10.5 3.3 0.88 9.3 0.6 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.17 EKG16469.1 - 1.2e-50 172.4 0.0 2.7e-50 171.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 DUF1772 PF08592.6 EKG16470.1 - 1.1e-16 60.8 0.7 1.3e-16 60.5 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SnoaL_2 PF12680.2 EKG16471.1 - 0.018 15.4 0.0 0.022 15.1 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain NmrA PF05368.8 EKG16472.1 - 2.6e-34 118.5 0.0 3.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG16472.1 - 2.2e-13 50.6 0.7 2.9e-13 50.2 0.5 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG16472.1 - 8.8e-07 28.5 0.0 1.8e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG16472.1 - 2e-05 23.4 0.0 2.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG16472.1 - 0.00014 20.9 0.0 0.0075 15.2 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 EKG16472.1 - 0.00017 21.2 0.3 0.00029 20.5 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKG16472.1 - 0.00068 19.5 0.8 0.0014 18.6 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EKG16472.1 - 0.049 12.5 0.1 0.16 10.7 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EKG16472.1 - 0.049 13.5 0.0 0.085 12.7 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EKG16472.1 - 0.11 11.4 0.2 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase MFS_1 PF07690.11 EKG16474.1 - 2.2e-38 131.8 49.2 2.2e-38 131.8 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EKG16476.1 - 6.5e-27 94.1 58.2 2.5e-23 82.3 21.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16476.1 - 2.1e-07 29.9 36.0 5.5e-05 21.9 13.1 2.6 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EKG16476.1 - 0.016 14.9 3.1 0.077 12.7 0.1 3.2 3 0 0 3 3 3 0 MFS_1 like family DUF3789 PF12664.2 EKG16476.1 - 0.097 11.9 0.0 0.097 11.9 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3789) ATP1G1_PLM_MAT8 PF02038.11 EKG16476.1 - 1.1 8.3 3.8 1.1 8.3 0.1 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family RIB43A PF05914.7 EKG16477.1 - 0.1 11.2 0.2 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 RIB43A CDC27 PF09507.5 EKG16479.1 - 1.2 8.2 7.8 2.3 7.3 5.4 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 COesterase PF00135.23 EKG16480.1 - 7.5e-89 298.8 0.0 9.5e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG16480.1 - 1e-06 28.4 0.1 7.3e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ank_2 PF12796.2 EKG16481.1 - 2.6e-13 50.1 1.0 1.9e-07 31.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG16481.1 - 4.9e-08 33.2 0.0 1.6e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG16481.1 - 7.6e-08 32.3 0.0 1.2e-06 28.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) CorA PF01544.13 EKG16481.1 - 3.4e-07 29.5 2.7 1.3e-06 27.7 1.9 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ank PF00023.25 EKG16481.1 - 8e-07 28.5 0.1 0.076 12.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EKG16481.1 - 0.00034 20.5 0.0 1.4 9.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat CorA PF01544.13 EKG16482.1 - 6.2e-09 35.3 1.0 9e-09 34.7 0.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M8 PF01457.11 EKG16482.1 - 0.071 11.4 0.0 0.092 11.0 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin RTA1 PF04479.8 EKG16483.1 - 8.1e-26 90.9 7.1 1.2e-25 90.3 4.9 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF2207 PF09972.4 EKG16483.1 - 0.52 8.8 2.3 0.64 8.5 1.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sugar_tr PF00083.19 EKG16485.1 - 4e-85 286.0 22.2 4.7e-85 285.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG16485.1 - 8.2e-22 77.3 45.3 7.2e-17 61.1 13.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EKG16485.1 - 0.022 14.7 8.2 1.5 8.9 0.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) FA_hydroxylase PF04116.8 EKG16487.1 - 3.4e-14 53.2 20.4 1.1e-13 51.6 11.2 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Glyco_hydro_76 PF03663.9 EKG16490.1 - 1.4e-58 199.0 6.6 1.8e-58 198.7 4.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EKG16490.1 - 0.0012 17.9 0.3 0.0014 17.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Gly_transf_sug PF04488.10 EKG16492.1 - 7.9e-18 64.7 0.0 1.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EKG16492.1 - 9e-05 21.1 1.4 0.12 10.8 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Fungal_lectin PF07938.7 EKG16493.1 - 2.7e-06 26.9 1.0 2.7e-06 26.9 0.7 2.0 1 1 0 2 2 2 1 Fungal fucose-specific lectin FtsH_ext PF06480.10 EKG16493.1 - 0.16 12.1 8.3 0.6 10.3 0.4 3.2 3 1 0 3 3 3 0 FtsH Extracellular TPP_enzyme_N PF02776.13 EKG16495.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MFS_1 PF07690.11 EKG16496.1 - 1.3e-29 103.0 18.2 6.6e-29 100.7 12.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MARVEL PF01284.18 EKG16496.1 - 0.32 10.7 17.1 1.5 8.6 1.3 4.0 2 1 2 4 4 4 0 Membrane-associating domain UCR_UQCRX_QCR9 PF05365.7 EKG16496.1 - 4.4 7.0 6.9 12 5.6 0.2 3.2 3 1 1 4 4 4 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like PI3_PI4_kinase PF00454.22 EKG16497.1 - 1.3e-43 149.1 0.1 3e-43 147.9 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EKG16497.1 - 5.7e-31 107.3 0.0 8e-30 103.6 0.0 2.7 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EKG16497.1 - 9e-10 37.8 0.4 2e-09 36.6 0.2 1.7 1 0 0 1 1 1 1 FATC domain DUF3414 PF11894.3 EKG16498.1 - 0 1384.2 10.5 0 1383.9 7.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) GFO_IDH_MocA PF01408.17 EKG16499.1 - 5.9e-07 30.0 0.0 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_S6 PF01250.12 EKG16500.1 - 8.7e-11 41.5 0.0 1.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 GCV_H PF01597.14 EKG16501.1 - 3.8e-38 129.9 0.3 4.5e-38 129.6 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein GFO_IDH_MocA_C PF02894.12 EKG16502.1 - 1.6e-13 50.4 0.0 3.7e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NmrA PF05368.8 EKG16503.1 - 1.8e-17 63.3 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG16503.1 - 1.5e-11 44.6 0.1 2.9e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG16503.1 - 0.00014 20.6 0.0 0.00023 19.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EKG16503.1 - 0.00017 21.2 2.2 0.01 15.5 0.5 2.6 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EKG16503.1 - 0.002 17.6 0.2 0.011 15.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EKG16503.1 - 0.0026 17.6 1.8 0.0068 16.3 0.2 2.2 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EKG16503.1 - 0.0043 16.0 2.4 0.069 12.0 0.5 2.3 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 EKG16503.1 - 0.04 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.12 EKG16503.1 - 0.043 14.2 0.2 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Acetyltransf_1 PF00583.19 EKG16505.1 - 1.4e-09 37.8 0.0 2.6e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EKG16505.1 - 5.7e-07 29.4 0.0 0.00011 22.0 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG16505.1 - 8.5e-07 29.1 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG16505.1 - 1.7e-05 24.8 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG16505.1 - 0.00069 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EKG16505.1 - 0.078 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 EKG16505.1 - 0.082 12.8 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease PF00324.16 EKG16506.1 - 4.6e-60 203.3 13.4 5.4e-60 203.0 9.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG16506.1 - 8.2e-17 60.8 16.6 1.1e-16 60.4 11.5 1.1 1 0 0 1 1 1 1 Amino acid permease Rick_17kDa_Anti PF05433.10 EKG16508.1 - 0.00071 19.1 11.4 0.00086 18.9 7.1 1.8 1 1 1 2 2 2 2 Glycine zipper 2TM domain DUF456 PF04306.8 EKG16508.1 - 0.013 15.5 0.2 0.018 15.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.1 EKG16508.1 - 0.018 14.6 10.3 0.044 13.4 7.1 1.7 1 0 0 1 1 1 0 Glycine zipper 4HBT PF03061.17 EKG16509.1 - 1.4e-07 31.5 0.0 1.9e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EKG16509.1 - 2.2e-06 28.1 0.0 2.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PseudoU_synth_2 PF00849.17 EKG16510.1 - 2.5e-30 105.4 0.0 5.5e-30 104.3 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EKG16510.1 - 0.005 16.2 0.3 0.011 15.1 0.2 1.5 1 0 0 1 1 1 1 S4 domain Crystall PF00030.14 EKG16511.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin HA2 PF04408.18 EKG16512.1 - 5.2e-17 61.7 0.5 3.1e-16 59.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EKG16512.1 - 6.7e-16 58.1 0.0 2e-15 56.6 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EKG16512.1 - 1.9e-12 46.8 0.0 5.9e-12 45.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EKG16512.1 - 2.2e-11 43.6 0.2 4.2e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EKG16512.1 - 1.7e-08 34.1 0.1 3.4e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EKG16512.1 - 0.00015 20.8 0.0 0.00028 19.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EKG16512.1 - 0.00057 20.0 0.1 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EKG16512.1 - 0.0025 17.0 0.0 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein UBA PF00627.26 EKG16512.1 - 0.0056 16.4 1.9 0.064 13.1 1.0 2.7 2 0 0 2 2 2 1 UBA/TS-N domain KaiC PF06745.8 EKG16512.1 - 0.012 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 EKG16512.1 - 0.016 14.7 0.1 0.048 13.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EKG16512.1 - 0.017 14.8 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EKG16512.1 - 0.05 13.0 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family ResIII PF04851.10 EKG16512.1 - 0.066 13.0 0.0 0.57 9.9 0.0 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EKG16512.1 - 0.2 10.4 0.0 0.36 9.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 EKG16512.1 - 0.38 11.0 0.0 0.38 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain DcpS_C PF11969.3 EKG16514.1 - 5.7e-17 62.0 1.7 8.5e-16 58.2 1.2 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EKG16514.1 - 1.4e-14 54.3 0.5 5.5e-14 52.4 0.4 1.9 1 1 0 1 1 1 1 HIT domain PTCB-BRCT PF12738.2 EKG16516.1 - 8.5e-35 118.4 5.0 1.3e-20 72.9 0.0 3.6 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EKG16516.1 - 6.9e-25 87.0 0.3 2.7e-12 46.6 0.0 4.2 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain Arrestin_C PF02752.17 EKG16517.1 - 3.5e-24 85.4 0.0 4.3e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EKG16517.1 - 4.7e-10 39.4 0.0 2.2e-05 24.3 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Na_H_Exchanger PF00999.16 EKG16518.1 - 6.2e-69 232.3 19.3 7.4e-69 232.0 13.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 EKG16518.1 - 3.6e-57 194.5 27.3 5.3e-57 194.0 18.9 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4190 PF13828.1 EKG16518.1 - 0.048 13.1 2.7 0.17 11.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) Porphobil_deam PF01379.15 EKG16519.1 - 5.4e-68 228.1 0.0 6e-44 149.5 0.0 2.3 2 0 0 2 2 2 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EKG16519.1 - 8e-18 64.3 0.4 1.7e-17 63.2 0.3 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain MKT1_C PF12246.3 EKG16520.1 - 5.8e-64 215.3 0.0 7.9e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EKG16520.1 - 1.1e-30 105.7 0.0 2.1e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EKG16520.1 - 3.4e-07 30.2 0.0 6.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EKG16520.1 - 1.7e-05 24.9 0.0 4.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain DIOX_N PF14226.1 EKG16521.1 - 2.4e-21 76.4 0.0 3.6e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG16521.1 - 1.1e-14 54.5 0.0 1.8e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PrpR_N PF06506.6 EKG16521.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Propionate catabolism activator Ribosomal_L7Ae PF01248.21 EKG16524.1 - 6.3e-22 76.9 3.3 1.6e-20 72.3 2.3 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3069 PF11269.3 EKG16524.1 - 2.1 8.4 5.8 1.8 8.6 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3069) NCKAP5 PF15246.1 EKG16524.1 - 6.9 5.9 13.2 0.45 9.8 5.7 1.5 2 0 0 2 2 2 0 Nck-associated protein 5, Peripheral clock protein SNF2_N PF00176.18 EKG16525.1 - 1.6e-71 240.6 0.0 2.1e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EKG16525.1 - 1.2e-19 70.1 0.0 2.5e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EKG16525.1 - 1.3e-13 50.6 0.0 2.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EKG16525.1 - 2.2e-07 30.8 7.8 4.3e-07 29.8 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EKG16525.1 - 6.1e-06 25.8 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EKG16525.1 - 0.00028 20.7 0.0 0.00076 19.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EKG16525.1 - 0.00031 20.3 8.1 0.00059 19.4 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG16525.1 - 0.00035 20.3 7.6 0.00071 19.3 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EKG16525.1 - 0.00035 20.1 6.7 0.00064 19.3 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PLU-1 PF08429.6 EKG16525.1 - 0.0025 16.7 0.9 0.0067 15.3 0.6 1.7 1 0 0 1 1 1 1 PLU-1-like protein zf-RING_5 PF14634.1 EKG16525.1 - 0.017 14.8 7.0 0.18 11.5 5.4 2.2 1 1 1 2 2 2 0 zinc-RING finger domain AAA_22 PF13401.1 EKG16525.1 - 0.12 12.5 0.0 0.93 9.6 0.0 2.6 1 1 0 1 1 1 0 AAA domain zf-C3HC4_4 PF15227.1 EKG16525.1 - 5 7.0 7.0 11 5.9 4.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.14 EKG16526.1 - 1.2e-46 159.2 0.6 1.8e-46 158.6 0.4 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Las1 PF04031.8 EKG16528.1 - 1.8e-47 160.8 0.6 2.8e-47 160.2 0.4 1.3 1 0 0 1 1 1 1 Las1-like Mpv17_PMP22 PF04117.7 EKG16530.1 - 1.7e-13 50.0 0.9 3.4e-11 42.5 0.3 2.2 2 0 0 2 2 2 2 Mpv17 / PMP22 family NADH_oxidored PF08040.6 EKG16530.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 MNLL subunit ABC2_membrane PF01061.19 EKG16532.1 - 1.9e-84 282.0 61.2 1.2e-49 168.3 14.1 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EKG16532.1 - 1.3e-37 129.1 0.0 1e-18 67.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG16532.1 - 2.6e-28 97.6 0.0 9.3e-28 95.9 0.0 2.0 1 0 0 1 1 1 1 CDR ABC transporter ABC_trans_N PF14510.1 EKG16532.1 - 3.9e-11 42.8 0.1 1.1e-10 41.3 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 EKG16532.1 - 1.2e-06 28.0 0.1 0.00028 20.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EKG16532.1 - 1.5e-06 28.0 0.0 0.0034 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EKG16532.1 - 4.2e-06 26.0 10.5 4.2e-06 26.0 7.3 2.6 2 0 0 2 2 2 1 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.13 EKG16532.1 - 6.7e-06 25.7 0.0 0.12 11.8 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EKG16532.1 - 1e-05 24.7 0.0 0.00091 18.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EKG16532.1 - 1.3e-05 24.5 0.3 0.13 11.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EKG16532.1 - 2.4e-05 25.1 0.1 0.0051 17.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKG16532.1 - 3.4e-05 24.0 0.1 0.071 13.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EKG16532.1 - 5e-05 23.4 4.6 0.0046 16.9 1.6 3.5 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EKG16532.1 - 5.8e-05 23.0 0.1 0.17 11.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EKG16532.1 - 8.4e-05 22.0 0.0 0.13 11.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EKG16532.1 - 0.00016 21.9 3.2 0.0029 17.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EKG16532.1 - 0.00022 21.2 0.6 0.0028 17.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG16532.1 - 0.00063 19.7 2.1 0.025 14.5 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain UPF0079 PF02367.12 EKG16532.1 - 0.00089 18.8 0.9 0.033 13.7 0.2 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 EKG16532.1 - 0.0024 17.1 1.1 0.068 12.3 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EKG16532.1 - 0.0037 16.9 0.5 0.33 10.5 0.2 2.4 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.18 EKG16532.1 - 0.015 15.1 1.8 0.14 11.9 0.0 3.2 4 0 0 4 4 4 0 Dynamin family AAA_24 PF13479.1 EKG16532.1 - 0.022 14.3 0.3 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EKG16532.1 - 0.023 15.2 0.1 0.58 10.6 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein NB-ARC PF00931.17 EKG16532.1 - 0.025 13.4 1.8 2 7.2 0.2 2.8 3 0 0 3 3 3 0 NB-ARC domain T2SE PF00437.15 EKG16532.1 - 0.028 13.3 0.0 6.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EKG16532.1 - 0.028 13.8 1.1 3.4 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain Septin PF00735.13 EKG16532.1 - 0.036 13.0 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Septin AAA PF00004.24 EKG16532.1 - 0.069 13.3 0.1 6.9 6.8 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EKG16532.1 - 0.09 12.0 0.1 0.81 8.9 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_15 PF13175.1 EKG16532.1 - 0.094 11.7 0.0 12 4.7 0.0 2.5 1 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EKG16532.1 - 0.1 12.0 0.7 0.46 9.9 0.2 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EKG16532.1 - 1 8.9 5.8 1.2 8.6 0.2 2.8 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EKG16532.1 - 3.9 7.7 9.2 15 5.8 0.1 3.9 4 1 0 4 4 3 0 AAA domain Vps16_N PF04841.8 EKG16533.1 - 7.1e-102 340.9 0.0 9.5e-102 340.5 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EKG16533.1 - 1.1e-89 300.5 0.1 2.9e-89 299.1 0.0 1.6 2 0 0 2 2 2 1 Vps16, C-terminal region Macro PF01661.16 EKG16534.1 - 9.9e-27 93.1 0.0 1.7e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Macro domain AA_permease PF00324.16 EKG16535.1 - 8.6e-139 462.9 43.9 9.7e-139 462.7 30.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG16535.1 - 3e-38 131.4 48.9 3e-38 131.4 33.9 1.5 1 1 0 1 1 1 1 Amino acid permease Glyco_hydro_61 PF03443.9 EKG16536.1 - 5.2e-62 209.5 0.6 6.4e-62 209.2 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PEX11 PF05648.9 EKG16537.1 - 6.5e-10 38.6 0.1 3.2e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) APG12 PF04110.8 EKG16537.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 SpoU_methylase PF00588.14 EKG16538.1 - 5.8e-25 87.8 0.0 1.1e-24 86.9 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family GRDA PF04723.9 EKG16538.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A Kinesin PF00225.18 EKG16539.1 - 1.5e-109 365.7 0.7 1.7e-109 365.5 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain DUF3573 PF12097.3 EKG16539.1 - 0.21 10.1 2.7 0.35 9.4 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 EKG16539.1 - 0.31 8.8 3.3 0.44 8.3 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 EKG16539.1 - 0.31 10.8 4.5 0.38 10.5 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function DUF87 DUF2721 PF11026.3 EKG16539.1 - 2.6 7.6 4.6 2.5 7.7 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) Mnd1 PF03962.10 EKG16539.1 - 3 7.4 7.5 5.6 6.5 5.2 1.4 1 0 0 1 1 1 0 Mnd1 family FAD_binding_3 PF01494.14 EKG16540.1 - 8.5e-28 97.4 0.3 2.5e-27 95.8 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG16540.1 - 2.3e-07 30.0 3.8 0.00032 19.6 0.4 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EKG16540.1 - 8.7e-06 25.0 0.1 0.00055 19.1 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EKG16540.1 - 3.3e-05 22.9 1.8 0.11 11.4 0.0 2.7 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.22 EKG16540.1 - 0.00072 19.9 1.2 0.029 14.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG16540.1 - 0.0015 18.5 0.1 0.0039 17.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG16540.1 - 0.0046 17.0 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG16540.1 - 0.016 13.6 0.1 3.6 5.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EKG16540.1 - 0.036 12.9 2.0 0.14 11.0 0.1 2.1 1 1 1 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EKG16540.1 - 0.052 13.4 0.2 0.12 12.2 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG16540.1 - 0.061 12.4 0.1 0.088 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EKG16540.1 - 0.1 11.2 0.9 0.46 9.0 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EKG16540.1 - 0.2 11.4 2.4 7.3 6.3 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_kinase PF01513.16 EKG16542.1 - 6.7e-71 238.3 0.0 9.3e-71 237.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EKG16542.1 - 0.022 14.2 0.0 0.049 13.0 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Lyase_1 PF00206.15 EKG16543.1 - 4e-20 72.2 0.0 6.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EKG16543.1 - 6.6e-15 54.8 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ADH_zinc_N PF00107.21 EKG16544.1 - 9.1e-11 41.4 0.0 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG16544.1 - 2.6e-09 36.7 0.0 5.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EKG16544.1 - 4.7e-06 27.5 0.0 1.1e-05 26.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KH_4 PF13083.1 EKG16544.1 - 0.21 11.2 0.9 1 9.0 0.0 2.3 2 0 0 2 2 2 0 KH domain bZIP_1 PF00170.16 EKG16546.1 - 5.4e-12 45.4 7.0 1.2e-11 44.4 4.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG16546.1 - 1e-07 31.6 3.6 1e-07 31.6 2.5 2.1 2 0 0 2 2 2 1 Basic region leucine zipper DUF1465 PF07323.7 EKG16546.1 - 0.01 15.4 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) bZIP_Maf PF03131.12 EKG16546.1 - 0.017 15.3 2.4 0.017 15.3 1.6 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.10 EKG16546.1 - 0.12 11.8 0.9 0.3 10.5 0.6 1.6 1 0 0 1 1 1 0 Septum formation initiator Tropomyosin_1 PF12718.2 EKG16546.1 - 0.14 12.0 6.2 0.037 13.8 1.8 1.9 2 0 0 2 2 2 0 Tropomyosin like Peptidase_S55 PF05580.7 EKG16550.1 - 0.085 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 SpoIVB peptidase S55 Ank_2 PF12796.2 EKG16551.1 - 9.9e-05 22.6 0.0 0.00095 19.4 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKG16551.1 - 0.0002 20.9 0.7 0.0013 18.4 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EKG16551.1 - 0.00047 20.1 0.2 0.038 14.2 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 EKG16551.1 - 0.0066 16.6 0.1 0.021 15.0 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) GxGYxYP PF14323.1 EKG16551.1 - 0.09 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function Muted PF14942.1 EKG16552.1 - 0.78 9.6 8.3 1.5 8.7 5.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Abhydrolase_3 PF07859.8 EKG16553.1 - 2.8e-14 53.1 0.0 4.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold NeA_P2 PF12312.3 EKG16553.1 - 0.028 13.6 0.2 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DLH PF01738.13 EKG16553.1 - 0.057 12.6 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family BBE PF08031.7 EKG16554.1 - 7.5e-11 41.7 0.5 1.1e-10 41.2 0.3 1.2 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EKG16554.1 - 0.063 12.4 0.1 0.081 12.0 0.1 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding RhgB_N PF09284.5 EKG16555.1 - 1.4e-114 381.6 3.3 2.2e-114 381.0 2.3 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EKG16555.1 - 3.6e-50 169.8 0.0 9e-50 168.5 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EKG16555.1 - 6.7e-19 67.8 2.2 6.7e-19 67.8 1.5 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EKG16555.1 - 0.0012 18.8 2.8 0.0012 18.8 1.9 2.7 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 EKG16555.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) p450 PF00067.17 EKG16556.1 - 4.3e-67 226.6 0.0 5.5e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HATPase_c PF02518.21 EKG16557.1 - 1.2e-22 79.7 0.0 4.4e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG16557.1 - 1.1e-18 67.2 0.0 2.2e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EKG16557.1 - 8.8e-11 41.6 4.9 1.1e-10 41.3 0.3 2.9 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain GATA PF00320.22 EKG16558.1 - 2.6e-15 55.4 4.3 4.4e-15 54.7 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_9 PF13426.1 EKG16558.1 - 0.0015 18.8 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_2 PF08446.6 EKG16558.1 - 0.0066 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EKG16558.1 - 0.032 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold DLIC PF05783.6 EKG16558.1 - 0.042 12.5 0.4 0.059 12.0 0.3 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Zn-ribbon_8 PF09723.5 EKG16558.1 - 0.13 12.2 0.6 0.27 11.2 0.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Peptidase_M16_C PF05193.16 EKG16560.1 - 2.8e-51 173.8 0.0 1.1e-50 171.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EKG16560.1 - 1.3e-39 135.2 0.0 3.7e-39 133.8 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Ribosomal_L35Ae PF01247.13 EKG16560.1 - 2.8e-37 126.3 0.1 6.9e-37 125.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EKG16560.1 - 0.0093 15.8 0.0 13 5.8 0.0 3.4 3 0 0 3 3 3 2 RimM N-terminal domain FHA PF00498.21 EKG16561.1 - 4.7e-15 55.4 0.0 8.2e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EKG16561.1 - 1e-07 31.6 8.6 1.9e-07 30.7 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKG16561.1 - 0.00021 21.3 3.6 0.00053 20.0 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKG16561.1 - 0.0061 16.1 8.3 0.014 15.0 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG16561.1 - 0.008 15.8 6.2 0.015 15.0 4.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKG16561.1 - 0.015 15.1 3.2 0.036 13.8 2.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EKG16561.1 - 0.069 13.1 10.3 0.14 12.2 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EKG16561.1 - 0.084 12.5 5.1 0.21 11.2 3.5 1.7 1 0 0 1 1 1 0 PHD-finger Vps39_2 PF10367.4 EKG16561.1 - 0.14 12.3 2.7 0.25 11.5 1.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 YokU PF14122.1 EKG16561.1 - 0.17 11.5 3.8 2.1 8.1 0.1 2.5 3 0 0 3 3 3 0 YokU-like protein zf-RING-like PF08746.6 EKG16561.1 - 0.37 10.8 5.7 1.1 9.3 3.9 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EKG16561.1 - 0.75 9.7 4.6 2.2 8.2 3.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING AAA_3 PF07726.6 EKG16562.1 - 0.082 12.5 0.1 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CDC14 PF08045.6 EKG16563.1 - 3.9e-91 304.7 0.0 4.5e-91 304.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Cu-oxidase PF00394.17 EKG16565.1 - 1.1e-34 119.6 0.1 7.3e-34 116.9 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG16565.1 - 8.5e-21 73.9 3.7 1.1e-17 63.7 0.6 3.9 4 0 0 4 4 4 1 Multicopper oxidase AAA PF00004.24 EKG16565.1 - 1.5e-18 67.2 0.0 2.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cu-oxidase_3 PF07732.10 EKG16565.1 - 2e-16 59.7 1.0 1.2e-14 53.9 0.1 2.7 2 0 0 2 2 2 1 Multicopper oxidase AAA_22 PF13401.1 EKG16565.1 - 0.00094 19.3 0.5 0.023 14.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG16565.1 - 0.0055 16.7 0.1 0.021 14.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 EKG16565.1 - 0.0066 15.9 0.1 0.56 9.6 0.0 2.4 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_5 PF07728.9 EKG16565.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EKG16565.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RuvB_N PF05496.7 EKG16565.1 - 0.21 10.6 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Nop14 PF04147.7 EKG16565.1 - 0.69 7.7 5.1 1.3 6.9 3.5 1.3 1 0 0 1 1 1 0 Nop14-like family MFS_1 PF07690.11 EKG16566.1 - 2.5e-05 23.1 16.4 3.2e-05 22.8 11.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16566.1 - 0.0013 17.4 11.6 0.0015 17.1 8.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1228 PF06779.9 EKG16566.1 - 0.021 14.8 3.6 0.024 14.6 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) Glutaredoxin PF00462.19 EKG16567.1 - 1.5e-15 56.9 0.0 9.1e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Musclin PF11037.3 EKG16567.1 - 0.038 13.6 0.5 0.08 12.5 0.3 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle GST_N_3 PF13417.1 EKG16567.1 - 0.062 13.5 0.0 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Serinc PF03348.10 EKG16567.1 - 0.26 9.9 0.8 0.37 9.4 0.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1510 PF07423.6 EKG16567.1 - 1.1 8.6 12.4 0.022 14.1 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) WD40 PF00400.27 EKG16570.1 - 8.5e-17 60.3 6.6 0.00026 20.7 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ATP_bind_1 PF03029.12 EKG16571.1 - 1.6e-73 247.1 0.0 2.9e-73 246.3 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Pyridox_oxase_2 PF12766.2 EKG16571.1 - 9.4e-24 83.6 0.0 1.7e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ArgK PF03308.11 EKG16571.1 - 0.00084 18.1 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EKG16571.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EKG16571.1 - 0.009 16.8 0.4 0.065 14.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EKG16571.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EKG16571.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EKG16571.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Fer4_NifH PF00142.13 EKG16571.1 - 0.22 10.6 0.2 0.86 8.7 0.0 2.0 2 1 1 3 3 3 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Ndc1_Nup PF09531.5 EKG16572.1 - 0.12 10.7 2.6 3.3 6.0 0.5 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF972 PF06156.8 EKG16573.1 - 0.26 11.6 3.1 8.5 6.7 2.2 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Glyco_hydro_92 PF07971.7 EKG16575.1 - 8.1e-160 532.7 0.0 1e-159 532.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyoxalase_2 PF12681.2 EKG16575.1 - 0.088 13.4 0.0 0.3 11.7 0.0 1.9 1 0 0 1 1 1 0 Glyoxalase-like domain ADH_zinc_N PF00107.21 EKG16576.1 - 4.5e-31 107.0 0.1 6.9e-31 106.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG16576.1 - 1.6e-16 61.3 0.0 4.6e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG16576.1 - 3e-09 36.5 0.0 6.4e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EKG16576.1 - 0.00036 20.5 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EKG16576.1 - 0.021 14.3 0.1 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EKG16576.1 - 0.048 13.2 0.1 0.078 12.5 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Hexokinase_1 PF00349.16 EKG16577.1 - 2.6e-26 92.2 0.0 3.2e-23 82.1 0.0 2.6 2 1 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.11 EKG16577.1 - 3.8e-23 81.9 0.0 1.9e-17 63.2 0.0 2.3 2 0 0 2 2 2 2 Hexokinase GILT PF03227.11 EKG16578.1 - 6e-15 55.0 0.2 1.1e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF3357 PF11837.3 EKG16578.1 - 0.081 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF1681 PF07933.9 EKG16579.1 - 4.6e-54 182.2 0.0 5.9e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) HAD PF12710.2 EKG16580.1 - 5.9e-11 42.8 0.0 1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EKG16580.1 - 6.3e-06 25.5 0.0 0.014 14.5 0.0 2.0 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 EKG16580.1 - 1.3e-05 25.5 0.0 6.5e-05 23.2 0.0 2.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EKG16580.1 - 0.0033 16.7 0.1 0.015 14.6 0.0 1.9 2 1 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) She9_MDM33 PF05546.6 EKG16581.1 - 6.3e-54 182.6 8.3 9e-54 182.1 5.8 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family DUF2564 PF10819.3 EKG16581.1 - 0.38 10.9 8.3 4.4 7.4 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) DUF4404 PF14357.1 EKG16581.1 - 1.2 9.6 8.8 0.26 11.7 3.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Ammonium_transp PF00909.16 EKG16582.1 - 9.7e-116 386.5 27.5 1.1e-115 386.3 19.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3482 PF11981.3 EKG16582.1 - 0.52 9.4 3.3 0.89 8.7 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) DUF4229 PF14012.1 EKG16582.1 - 7.2 6.5 8.5 11 5.9 2.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Lon_C PF05362.8 EKG16583.1 - 5.6e-69 231.5 0.2 1.1e-68 230.5 0.1 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EKG16583.1 - 1.1e-29 103.5 1.4 1.3e-29 103.3 0.0 1.8 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EKG16583.1 - 3.9e-24 85.3 0.0 1.1e-23 83.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG16583.1 - 3.2e-09 36.6 0.0 1.7e-08 34.3 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EKG16583.1 - 4.6e-08 32.6 0.5 6.6e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EKG16583.1 - 8.6e-06 25.8 2.5 1.8e-05 24.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EKG16583.1 - 1.3e-05 25.1 0.0 5.4e-05 23.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EKG16583.1 - 1.4e-05 25.8 0.2 8.1e-05 23.4 0.0 2.5 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EKG16583.1 - 1.8e-05 24.2 0.0 3.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EKG16583.1 - 3.5e-05 22.6 0.0 0.00013 20.8 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_3 PF07726.6 EKG16583.1 - 4.9e-05 22.9 0.0 0.00016 21.2 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EKG16583.1 - 6.4e-05 22.6 0.0 0.00024 20.7 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EKG16583.1 - 6.6e-05 22.0 0.1 0.00073 18.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EKG16583.1 - 0.00036 20.4 0.6 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKG16583.1 - 0.0005 20.2 0.0 0.0041 17.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EKG16583.1 - 0.00075 18.9 0.0 0.0021 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EKG16583.1 - 0.0032 16.6 1.6 0.0079 15.3 0.1 2.2 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EKG16583.1 - 0.0065 16.3 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EKG16583.1 - 0.008 14.9 0.0 0.52 8.9 0.0 2.3 2 0 0 2 2 2 1 PrkA AAA domain G-alpha PF00503.15 EKG16583.1 - 0.013 14.2 0.0 0.029 13.0 0.0 1.5 1 0 0 1 1 1 0 G-protein alpha subunit Mg_chelatase PF01078.16 EKG16583.1 - 0.014 14.5 0.1 0.043 12.9 0.1 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EKG16583.1 - 0.016 14.9 0.0 0.2 11.2 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EKG16583.1 - 0.016 15.3 0.0 0.074 13.2 0.0 2.0 1 1 1 2 2 2 0 RNA helicase AAA_30 PF13604.1 EKG16583.1 - 0.022 14.3 0.6 0.052 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EKG16583.1 - 0.022 14.3 0.1 0.044 13.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EKG16583.1 - 0.025 14.2 0.1 0.1 12.2 0.0 2.1 2 0 0 2 2 1 0 NACHT domain PhoH PF02562.11 EKG16583.1 - 0.028 13.6 0.0 0.076 12.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 EKG16583.1 - 0.028 14.0 0.2 0.075 12.6 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EKG16583.1 - 0.035 14.4 0.9 0.097 12.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 EKG16583.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EKG16583.1 - 0.055 13.7 0.0 0.055 13.7 0.0 3.0 1 1 1 2 2 1 0 AAA domain AAA_11 PF13086.1 EKG16583.1 - 0.3 10.6 0.0 0.3 10.6 0.0 2.7 1 1 1 2 2 1 0 AAA domain Rrn6 PF10214.4 EKG16584.1 - 2.7e-68 230.8 0.0 3.8e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EKG16585.1 - 1.5e-18 66.5 0.1 3.2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Filament PF00038.16 EKG16585.1 - 0.016 14.7 12.5 0.023 14.1 8.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein Polysacc_deac_3 PF15421.1 EKG16585.1 - 0.017 13.8 0.2 0.026 13.2 0.1 1.3 1 1 0 1 1 1 0 Putative polysaccharide deacetylase Cortex-I_coil PF09304.5 EKG16585.1 - 0.052 13.5 10.9 0.12 12.4 7.6 1.6 1 0 0 1 1 1 0 Cortexillin I, coiled coil Seryl_tRNA_N PF02403.17 EKG16585.1 - 0.87 9.6 13.4 1.6 8.7 9.3 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.14 EKG16585.1 - 0.96 8.9 20.0 1.4 8.3 13.8 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FUSC PF04632.7 EKG16585.1 - 1.2 7.4 3.7 1.1 7.5 2.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family BTV_NS2 PF04514.7 EKG16585.1 - 1.7 7.4 9.2 2.4 6.9 6.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 APG6 PF04111.7 EKG16585.1 - 1.8 7.5 11.5 2.7 6.9 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EKG16585.1 - 2.6 7.6 15.6 3.5 7.2 9.2 1.9 1 1 1 2 2 2 0 Mnd1 family Atg14 PF10186.4 EKG16585.1 - 4.3 6.1 17.2 6.9 5.5 11.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HA2 PF04408.18 EKG16586.1 - 4.6e-21 74.7 0.1 1e-20 73.6 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKG16586.1 - 3.1e-14 52.6 0.0 5.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EKG16586.1 - 6.8e-09 35.5 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EKG16586.1 - 0.038 13.4 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF2611 PF11022.3 EKG16586.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) CUE PF02845.11 EKG16587.1 - 7.2e-12 44.5 0.0 1.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain Arginase PF00491.16 EKG16588.1 - 5.4e-72 242.4 0.9 8.2e-71 238.5 0.6 2.0 1 1 0 1 1 1 1 Arginase family Cyt-b5 PF00173.23 EKG16589.1 - 3.6e-07 29.8 0.0 4.4e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 EKG16590.1 - 5.7e-63 208.4 0.1 3.7e-18 64.9 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG16590.1 - 2e-49 165.4 0.0 6.9e-16 57.9 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG16590.1 - 4.3e-22 77.7 0.2 1.1e-07 31.6 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKG16590.1 - 0.0014 18.3 0.0 0.3 10.8 0.0 4.0 3 0 0 3 3 3 1 Limkain b1 CDC45 PF02724.9 EKG16590.1 - 0.0027 15.8 13.2 0.0027 15.8 9.2 2.4 2 0 0 2 2 2 1 CDC45-like protein GMC_oxred_N PF00732.14 EKG16591.1 - 1.4e-65 221.4 0.0 2.1e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG16591.1 - 1.1e-39 136.0 0.1 1.9e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG16591.1 - 3.3e-11 42.6 2.8 1.1e-10 41.0 1.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG16591.1 - 3.8e-06 26.0 0.0 0.026 13.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG16591.1 - 9.8e-05 22.3 0.0 0.00036 20.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG16591.1 - 0.0054 16.8 0.1 0.078 13.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG16591.1 - 0.0068 15.3 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EKG16591.1 - 0.0071 14.8 0.1 0.03 12.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EKG16591.1 - 0.0077 16.0 0.1 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EKG16591.1 - 0.045 13.6 0.1 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG16591.1 - 0.06 13.7 0.3 0.91 9.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EKG16592.1 - 1.3e-19 70.0 0.1 2.1e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-grasp_4 PF13535.1 EKG16592.1 - 4.1e-14 52.7 0.0 8.6e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Zn_clus PF00172.13 EKG16592.1 - 6.6e-09 35.5 6.5 1.3e-08 34.5 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dala_Dala_lig_C PF07478.8 EKG16592.1 - 0.00015 21.2 0.0 0.00043 19.7 0.0 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EKG16592.1 - 0.034 12.8 0.0 0.074 11.7 0.0 1.4 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EKG16592.1 - 0.037 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EKG16592.1 - 0.088 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain Dabb PF07876.7 EKG16593.1 - 1.9e-14 53.8 0.1 2.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain ECH PF00378.15 EKG16594.1 - 3.4e-40 137.7 0.0 7.1e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 EKG16594.1 - 8.1e-38 130.4 0.0 1.5e-37 129.5 0.0 1.5 1 0 0 1 1 1 1 HMGL-like DUF1800 PF08811.6 EKG16594.1 - 0.043 12.7 1.1 0.31 9.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) AMP-binding PF00501.23 EKG16595.1 - 4.8e-31 107.5 0.0 9.7e-26 90.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Carboxyl_trans PF01039.17 EKG16596.1 - 6.5e-116 387.5 0.0 7.8e-116 387.3 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Fungal_trans PF04082.13 EKG16596.1 - 1.2e-19 70.1 0.5 2e-19 69.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG16596.1 - 1e-05 25.3 2.4 1.9e-05 24.4 1.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EKG16597.1 - 1.1e-29 103.4 0.7 1.8e-29 102.7 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG16597.1 - 1.1e-21 77.5 0.0 4.7e-21 75.4 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EKG16597.1 - 6.8e-20 70.3 0.6 1.2e-19 69.5 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EKG16597.1 - 5.7e-05 23.3 0.7 9e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CPSase_L_D2 PF02786.12 EKG16598.1 - 1.2e-53 181.5 0.2 3.4e-53 180.0 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EKG16598.1 - 8.6e-34 115.7 0.0 1.7e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EKG16598.1 - 5.3e-14 51.6 0.2 1e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EKG16598.1 - 2.1e-08 34.1 0.4 3.8e-08 33.2 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG16598.1 - 0.002 16.9 0.2 0.0046 15.7 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EKG16598.1 - 0.012 14.9 0.2 0.027 13.8 0.1 1.7 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_3 PF02655.9 EKG16598.1 - 0.016 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.14 EKG16598.1 - 0.041 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein Dala_Dala_lig_C PF07478.8 EKG16598.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF1528 PF07515.6 EKG16599.1 - 0.0068 16.4 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1528) Glyco_hydro_48 PF02011.10 EKG16600.1 - 0.0075 14.4 0.2 0.011 13.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 48 DUF829 PF05705.9 EKG16601.1 - 4.8e-49 167.2 0.0 7.1e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) p450 PF00067.17 EKG16602.1 - 1.3e-17 63.5 0.0 1.5e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG16603.1 - 1.8e-08 33.3 0.0 2.2e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.19 EKG16606.1 - 2.5e-11 43.5 8.6 3.2e-11 43.1 5.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase SNF PF00209.13 EKG16607.1 - 2.6e-69 234.0 31.6 2.6e-69 234.0 21.9 2.3 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family DUF1744 PF08490.7 EKG16608.1 - 7.1e-147 489.1 0.1 9.8e-147 488.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EKG16608.1 - 9.6e-66 221.8 0.7 2.3e-65 220.5 0.5 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EKG16608.1 - 8.8e-21 74.2 0.2 4.4e-20 71.9 0.3 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EKG16608.1 - 1.3e-08 34.6 0.0 3.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EKG16608.1 - 3e-05 23.8 0.0 0.00013 21.8 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.3 EKG16609.1 - 9.8e-32 109.1 0.0 9.8e-32 109.1 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) DUF1311 PF07007.7 EKG16609.1 - 0.37 10.9 5.3 0.63 10.1 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) HDAC4_Gln PF12203.3 EKG16609.1 - 0.75 9.7 7.4 1.1 9.2 5.1 1.2 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 DUF1509 PF07420.6 EKG16610.1 - 0.027 13.7 11.7 0.045 13.0 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) QRPTase_C PF01729.14 EKG16611.1 - 6.6e-54 181.9 0.1 8.2e-54 181.6 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EKG16611.1 - 4.7e-24 84.0 0.0 1.3e-23 82.5 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 EKG16611.1 - 0.16 11.0 0.6 0.65 9.0 0.0 1.9 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family F-box-like PF12937.2 EKG16612.1 - 1.9e-09 37.0 0.2 5.9e-09 35.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG16612.1 - 0.082 12.5 2.2 0.16 11.6 0.2 2.5 2 0 0 2 2 2 0 F-box domain TSKS PF15358.1 EKG16612.1 - 0.17 10.0 0.0 0.24 9.5 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Peptidase_M35 PF02102.10 EKG16613.1 - 1.8e-91 306.5 15.0 2.1e-91 306.2 10.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EKG16613.1 - 2.5e-07 31.3 0.2 4.7e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase HSL_N PF06350.7 EKG16616.1 - 0.052 12.6 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus MAPEG PF01124.13 EKG16617.1 - 2.1e-17 62.9 1.2 3.8e-17 62.0 0.8 1.4 1 1 0 1 1 1 1 MAPEG family Pectate_lyase_3 PF12708.2 EKG16619.1 - 1.9e-80 270.2 26.9 3.3e-67 226.9 8.2 3.8 6 0 0 6 6 6 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EKG16619.1 - 2.8e-06 26.6 0.8 0.036 13.5 0.1 3.0 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase MFS_1 PF07690.11 EKG16620.1 - 7.7e-35 120.2 52.1 7.7e-35 120.2 36.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16620.1 - 1.5e-06 27.0 17.1 1.5e-06 27.0 11.8 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4604 PF15377.1 EKG16620.1 - 0.28 11.4 13.9 0.41 10.8 9.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Aminotran_1_2 PF00155.16 EKG16621.1 - 3.2e-59 200.7 0.0 3.7e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MetW PF07021.7 EKG16621.1 - 0.11 11.8 0.0 0.63 9.3 0.0 2.1 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Lactamase_B PF00753.22 EKG16622.1 - 1.2e-19 70.6 0.7 2e-19 69.9 0.5 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG16622.1 - 3.8e-05 23.3 0.1 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain N6-adenineMlase PF10237.4 EKG16623.1 - 7.6e-52 175.2 0.0 9.2e-52 174.9 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 EKG16623.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EKG16623.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain HIT PF01230.18 EKG16624.1 - 3.7e-23 81.9 1.3 3.8e-23 81.8 0.3 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EKG16624.1 - 1.2e-13 51.3 0.1 1.6e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EKG16624.1 - 9.7e-06 25.2 0.1 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.20 EKG16625.1 - 1.3e-68 231.0 0.0 1.6e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG16625.1 - 6.7e-29 100.7 0.0 8.6e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG16625.1 - 1e-06 27.9 0.0 1.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG16625.1 - 0.00027 20.7 0.0 0.00046 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EKG16625.1 - 0.001 18.1 0.0 0.0023 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKG16625.1 - 0.051 12.8 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF2370 PF10176.4 EKG16626.1 - 1.2e-81 273.4 0.3 2.2e-81 272.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EKG16626.1 - 0.1 12.8 0.2 0.63 10.3 0.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) HTH_Tnp_Tc5 PF03221.11 EKG16627.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain HUN PF08729.5 EKG16628.1 - 2.2e-12 46.6 0.9 3.8e-12 45.8 0.7 1.4 1 0 0 1 1 1 1 HPC2 and ubinuclein domain RPAP1_C PF08620.5 EKG16629.1 - 7.8e-29 99.3 0.1 1.8e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EKG16629.1 - 7e-18 63.9 3.8 1.3e-17 63.0 2.7 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 EKG16629.1 - 0.14 12.3 0.1 0.45 10.7 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat TBCC PF07986.7 EKG16630.1 - 4.8e-34 116.3 0.0 7.2e-34 115.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Tim17 PF02466.14 EKG16631.1 - 2.8e-14 53.2 4.5 3.7e-14 52.8 3.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EKG16631.1 - 1.8 8.7 5.8 0.31 11.1 0.3 2.2 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide UCH PF00443.24 EKG16632.1 - 2.5e-41 141.5 0.1 7.2e-41 140.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EKG16632.1 - 1.9e-15 56.0 0.3 6.9e-10 38.1 0.0 4.0 4 0 0 4 4 4 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EKG16632.1 - 2.2e-12 47.0 0.6 9.4e-07 28.5 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase AXE1 PF05448.7 EKG16633.1 - 0.088 11.2 0.3 0.14 10.6 0.2 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF463 PF04317.7 EKG16633.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 DUF3809 PF12723.2 EKG16633.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) DUF3136 PF11334.3 EKG16634.1 - 0.67 9.4 5.9 8.5 5.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3136) SAM_1 PF00536.25 EKG16636.1 - 2.1e-17 63.0 0.0 3.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EKG16636.1 - 2.4e-17 62.5 0.0 3.9e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EKG16636.1 - 7.5e-16 58.3 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PRP38_assoc PF12871.2 EKG16636.1 - 0.018 15.5 12.7 0.018 15.5 8.8 2.5 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term TMF_TATA_bd PF12325.3 EKG16636.1 - 0.083 12.6 0.7 0.14 11.8 0.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SAM_PNT PF02198.11 EKG16636.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF972 PF06156.8 EKG16636.1 - 0.17 12.2 0.1 0.33 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF1777 PF08648.7 EKG16636.1 - 0.78 9.4 15.9 0.041 13.6 4.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) EnY2 PF10163.4 EKG16637.1 - 0.0002 21.2 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 HTH_20 PF12840.2 EKG16637.1 - 0.054 13.3 0.5 0.13 12.0 0.1 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3453 PF11935.3 EKG16637.1 - 0.08 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) VirionAssem_T7 PF11653.3 EKG16637.1 - 3.9 8.3 8.4 3.4 8.4 0.8 2.7 3 0 0 3 3 3 0 Bacteriophage T7 virion assembly protein AAA PF00004.24 EKG16638.1 - 7.5e-97 320.6 0.0 6.7e-47 158.9 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EKG16638.1 - 5.1e-20 71.2 0.4 1.4e-19 69.8 0.3 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EKG16638.1 - 8.8e-14 51.7 0.0 9.2e-08 32.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EKG16638.1 - 2.1e-13 49.9 0.0 7.8e-06 25.1 0.0 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EKG16638.1 - 9.1e-13 48.3 0.0 1.5e-05 24.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EKG16638.1 - 1.8e-11 44.3 0.3 0.0024 18.0 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EKG16638.1 - 2.2e-11 43.6 0.6 8.7e-06 25.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKG16638.1 - 2.7e-11 43.8 0.0 0.00084 19.3 0.0 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EKG16638.1 - 2.9e-11 44.2 0.0 0.00058 20.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EKG16638.1 - 3.9e-09 35.7 0.1 0.0009 18.0 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EKG16638.1 - 1.8e-08 34.0 4.0 0.021 14.2 0.0 4.5 2 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 EKG16638.1 - 6.7e-08 32.1 0.0 0.0065 15.9 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EKG16638.1 - 8.1e-08 31.9 1.5 0.0039 16.8 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 EKG16638.1 - 1.1e-07 31.8 0.0 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EKG16638.1 - 3.3e-07 29.6 0.3 0.03 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EKG16638.1 - 3.4e-07 29.6 0.8 0.35 9.9 0.0 3.4 2 1 1 3 3 3 2 KaiC Zeta_toxin PF06414.7 EKG16638.1 - 3.8e-07 29.4 0.0 0.0065 15.5 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 EKG16638.1 - 6.1e-07 29.5 0.0 0.028 14.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase CDC48_2 PF02933.12 EKG16638.1 - 9e-07 28.4 0.0 2.5e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 ResIII PF04851.10 EKG16638.1 - 3.3e-06 27.0 0.0 0.0033 17.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EKG16638.1 - 3.8e-06 27.2 0.0 0.068 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EKG16638.1 - 8.6e-06 25.8 0.1 0.17 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.1 EKG16638.1 - 9.2e-06 25.3 0.2 0.16 11.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 EKG16638.1 - 1.5e-05 24.0 0.0 0.011 14.6 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EKG16638.1 - 2.4e-05 23.3 0.1 0.082 11.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EKG16638.1 - 4.7e-05 22.9 0.0 0.4 10.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EKG16638.1 - 6e-05 22.8 0.1 9.4 5.8 0.0 3.9 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EKG16638.1 - 7.2e-05 22.8 0.0 0.33 10.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EKG16638.1 - 8.5e-05 22.8 0.0 0.35 11.1 0.0 3.5 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 EKG16638.1 - 9.3e-05 21.7 0.3 0.3 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Bac_DnaA PF00308.13 EKG16638.1 - 0.0001 22.0 0.0 0.4 10.2 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein Vps4_C PF09336.5 EKG16638.1 - 0.00015 21.5 0.1 0.00074 19.3 0.1 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NACHT PF05729.7 EKG16638.1 - 0.00027 20.6 0.1 0.63 9.6 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 EKG16638.1 - 0.0004 19.9 0.0 0.9 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EKG16638.1 - 0.00054 19.0 0.0 0.63 8.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EKG16638.1 - 0.00071 19.2 0.0 0.87 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EKG16638.1 - 0.00094 18.8 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EKG16638.1 - 0.0017 17.2 0.1 0.75 8.6 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain NTPase_1 PF03266.10 EKG16638.1 - 0.0021 17.7 0.3 1 9.0 0.0 3.7 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 EKG16638.1 - 0.008 15.7 0.0 0.53 9.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EKG16638.1 - 0.017 14.1 0.3 0.99 8.3 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain IPT PF01745.11 EKG16638.1 - 0.026 13.6 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 EKG16638.1 - 0.029 13.2 0.0 2.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Zot PF05707.7 EKG16638.1 - 0.035 13.5 0.5 12 5.2 0.1 3.8 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) SKI PF01202.17 EKG16638.1 - 0.094 12.5 0.0 9.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 EKG16638.1 - 0.12 11.5 0.4 19 4.3 0.0 3.1 3 0 0 3 3 3 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EKG16638.1 - 0.16 11.6 0.1 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Abhydrolase_6 PF12697.2 EKG16640.1 - 3.1e-25 89.3 0.0 6.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG16640.1 - 5.8e-12 45.5 0.0 2.2e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG16640.1 - 7e-12 45.3 0.0 4.1e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EKG16640.1 - 0.0017 18.1 0.1 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PCI PF01399.22 EKG16641.1 - 1.7e-10 41.1 0.0 1.7e-10 41.1 0.0 2.9 3 0 0 3 3 3 1 PCI domain G-gamma PF00631.17 EKG16642.1 - 8.3e-22 76.7 0.0 9.7e-22 76.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain PUB PF09409.5 EKG16642.1 - 0.075 12.8 0.0 0.088 12.5 0.0 1.1 1 0 0 1 1 1 0 PUB domain HLH PF00010.21 EKG16643.1 - 6.7e-16 57.7 0.7 1.7e-15 56.3 0.5 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SIR2 PF02146.12 EKG16644.1 - 9e-06 25.5 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Mito_carr PF00153.22 EKG16646.1 - 1.6e-73 242.4 0.1 3.3e-26 90.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EKG16646.1 - 2.5e-16 57.6 3.7 1.2e-07 30.5 0.0 5.2 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.1 EKG16646.1 - 2.9e-14 51.5 3.4 8.9e-07 28.2 0.0 5.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 EKG16646.1 - 7.5e-14 51.6 4.9 2.1e-07 30.9 0.3 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EKG16646.1 - 6.6e-11 41.0 3.4 6.7e-06 25.1 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EKG16646.1 - 4.9e-10 38.8 6.1 0.12 11.9 0.0 5.4 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_9 PF14658.1 EKG16646.1 - 0.043 13.7 0.1 14 5.6 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain zf-C2H2_4 PF13894.1 EKG16647.1 - 3.9e-08 33.0 10.5 0.00076 19.6 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG16647.1 - 6.4e-07 29.3 10.0 0.0056 16.9 1.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG16647.1 - 0.0093 16.2 14.4 0.98 9.8 0.2 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-Di19 PF05605.7 EKG16647.1 - 0.094 12.8 6.1 0.18 11.9 0.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Orn_Arg_deC_N PF02784.11 EKG16648.1 - 2.5e-39 134.9 0.0 3.2e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EKG16648.1 - 4.6e-14 52.1 0.0 6.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EKG16648.1 - 0.002 17.4 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Meth_synt_2 PF01717.13 EKG16649.1 - 3.9e-21 75.3 0.0 5.1e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EKG16649.1 - 6.2e-09 35.5 0.0 0.00097 18.4 0.0 2.9 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Arf PF00025.16 EKG16650.1 - 3.5e-64 215.2 0.0 3.9e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EKG16650.1 - 1.5e-10 40.3 0.1 5.6e-07 28.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EKG16650.1 - 2.1e-08 33.5 0.0 2.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EKG16650.1 - 1.2e-06 28.4 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EKG16650.1 - 1.7e-06 27.4 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG16650.1 - 3.6e-06 27.4 0.0 5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EKG16650.1 - 0.00035 19.7 0.0 0.00037 19.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKG16650.1 - 0.024 14.0 0.0 0.74 9.2 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EKG16650.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 EKG16651.1 - 9.1e-56 189.4 14.2 1.2e-55 189.1 9.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Extensin_2 PF04554.8 EKG16651.1 - 1.9 8.4 27.6 7.7 6.4 14.6 3.0 2 1 0 2 2 2 0 Extensin-like region Metallophos PF00149.23 EKG16654.1 - 1.5e-15 57.1 1.8 3.3e-15 56.0 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG16654.1 - 5.7e-06 26.2 0.7 1.3e-05 25.1 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Epimerase_2 PF02350.14 EKG16654.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase P22_CoatProtein PF11651.3 EKG16654.1 - 0.3 9.6 0.0 0.43 9.1 0.0 1.2 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 GCD14 PF08704.5 EKG16655.1 - 1.3e-07 31.3 0.2 5.8e-06 25.9 0.1 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_24 PF13578.1 EKG16655.1 - 0.054 14.3 1.9 1.8 9.4 1.3 2.5 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase_6 PF13344.1 EKG16656.1 - 1.5e-29 101.8 0.0 3.3e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG16656.1 - 4.4e-13 50.1 0.0 6.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG16656.1 - 6.5e-11 41.7 0.0 1.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EKG16656.1 - 2.4e-07 31.1 0.1 2.5e-05 24.5 0.1 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PhoD PF09423.5 EKG16656.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase DNA_primase_lrg PF04104.9 EKG16657.1 - 1.1e-78 264.1 0.0 1.8e-78 263.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Glyco_hydro_88 PF07470.8 EKG16660.1 - 9.7e-66 222.0 2.3 1.2e-65 221.8 1.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 FA_desaturase PF00487.19 EKG16661.1 - 6.9e-12 45.3 27.0 6.9e-12 45.3 18.7 1.8 1 1 1 2 2 2 1 Fatty acid desaturase DUF218 PF02698.12 EKG16664.1 - 2.5e-14 53.0 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Meth_synt_2 PF01717.13 EKG16665.1 - 0.0052 15.8 0.0 0.0076 15.2 0.0 1.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain FAD_binding_4 PF01565.18 EKG16666.1 - 7.2e-12 44.9 0.1 1.2e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EKG16668.1 - 1.1e-49 169.0 26.8 1.1e-49 169.0 18.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16668.1 - 1.4e-18 66.7 20.2 1.8e-18 66.3 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EKG16668.1 - 2.2e-06 26.0 2.7 3.1e-06 25.5 0.5 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 EKG16668.1 - 5e-05 21.5 9.3 0.0014 16.7 0.1 2.6 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.8 EKG16668.1 - 0.00073 17.8 3.1 0.0014 16.9 2.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EKG16669.1 - 7.4e-44 150.0 0.0 1.2e-42 146.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 EKG16670.1 - 1.2e-80 270.8 0.1 9.9e-55 185.8 0.0 2.2 1 1 1 2 2 2 2 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EKG16670.1 - 7.5e-22 78.2 0.0 1.2e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SR-25 PF10500.4 EKG16670.1 - 2.5 7.4 9.3 3.9 6.8 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAD_binding_3 PF01494.14 EKG16671.1 - 1.7e-38 132.6 0.1 2.3e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 EKG16675.1 - 1.5e-28 99.5 26.2 8.3e-20 70.7 2.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16675.1 - 2.8e-18 65.7 17.6 3.2e-17 62.2 12.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter ESSS PF10183.4 EKG16676.1 - 6.3e-25 87.6 0.7 7.8e-25 87.3 0.5 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glycophorin_A PF01102.13 EKG16677.1 - 0.0003 20.5 0.0 0.00064 19.4 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A DUF4131 PF13567.1 EKG16677.1 - 0.1 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Podoplanin PF05808.6 EKG16677.1 - 0.7 9.4 6.2 0.044 13.3 0.3 1.9 2 0 0 2 2 2 0 Podoplanin Adeno_E3_CR2 PF02439.10 EKG16677.1 - 5.4 6.6 5.6 11 5.6 3.9 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Abhydrolase_6 PF12697.2 EKG16678.1 - 1.2e-18 67.8 3.2 5.4e-18 65.7 2.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG16678.1 - 9.8e-09 35.1 0.0 0.00056 19.6 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG16678.1 - 2.9e-08 33.5 0.0 5.7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FA_hydroxylase PF04116.8 EKG16679.1 - 8e-06 26.2 8.9 8e-06 26.2 6.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 EKG16680.1 - 1.8e-35 121.4 0.1 3.2e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 EKG16681.1 - 5.8e-25 87.2 0.0 8.9e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CDC27 PF09507.5 EKG16682.1 - 5e-92 309.3 26.0 5.6e-92 309.2 18.0 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 TFCD_C PF12612.3 EKG16683.1 - 5.2e-32 110.8 3.4 7.6e-32 110.2 0.3 2.8 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EKG16683.1 - 5e-06 26.1 7.0 0.041 13.9 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EKG16683.1 - 0.014 15.7 0.2 0.15 12.4 0.0 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EKG16683.1 - 0.11 12.8 6.8 0.21 11.8 0.1 4.6 5 0 0 5 5 5 0 HEAT repeats Trp_DMAT PF11991.3 EKG16683.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase HEAT_EZ PF13513.1 EKG16683.1 - 0.26 11.8 0.0 0.26 11.8 0.0 6.4 8 1 0 8 8 8 0 HEAT-like repeat RRM_1 PF00076.17 EKG16684.1 - 8.9e-12 44.4 0.0 1.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG16684.1 - 1.2e-06 28.3 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG16684.1 - 0.0065 16.2 0.0 0.0086 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EKG16685.1 - 3.5e-66 222.4 2.1 4.8e-66 222.0 1.4 1.2 1 0 0 1 1 1 1 ATP synthase subunit D GAS PF13851.1 EKG16685.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding GST_C PF00043.20 EKG16685.1 - 0.18 11.7 0.8 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Nup54 PF13874.1 EKG16685.1 - 0.55 9.8 4.3 0.25 10.9 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 ARGLU PF15346.1 EKG16685.1 - 4.8 6.9 16.0 3.5 7.4 0.1 2.5 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 TPR_12 PF13424.1 EKG16686.1 - 7.2e-11 41.8 1.0 3.9 7.4 0.0 7.2 6 1 1 7 7 7 1 Tetratricopeptide repeat Suf PF05843.9 EKG16686.1 - 1.8e-09 37.7 8.0 0.037 13.7 0.0 5.6 3 1 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EKG16686.1 - 2.9e-09 36.7 20.5 1.5 9.6 0.0 11.4 9 3 5 14 14 13 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG16686.1 - 3.2e-07 29.7 12.3 0.075 12.9 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EKG16686.1 - 3.4e-07 29.6 7.0 0.00077 18.5 1.6 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKG16686.1 - 3.6e-07 29.7 5.7 2.4 7.8 0.0 7.3 7 1 0 7 7 7 2 TPR repeat TPR_19 PF14559.1 EKG16686.1 - 1.9e-06 28.1 1.1 5 7.5 0.0 6.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG16686.1 - 4.6e-06 26.0 1.2 0.32 10.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG16686.1 - 9.8e-05 22.9 8.5 2.2 9.0 0.0 6.4 7 1 1 8 8 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EKG16686.1 - 0.0013 18.5 11.6 0.65 9.7 0.1 6.3 8 1 1 9 9 8 1 Mad3/BUB1 homology region 1 RPN7 PF10602.4 EKG16686.1 - 0.0025 17.2 0.5 0.011 15.1 0.2 2.3 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 EKG16686.1 - 0.0036 16.9 9.1 0.31 10.9 0.0 6.7 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG16686.1 - 0.01 16.2 4.3 61 4.4 0.0 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKG16686.1 - 0.029 14.5 10.9 1.4 9.3 0.0 6.3 9 0 0 9 9 6 0 Tetratricopeptide repeat HAT PF02184.11 EKG16686.1 - 3.5 7.4 13.8 2.6 7.8 0.0 6.6 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat Dehydrin PF00257.14 EKG16687.1 - 0.017 15.4 0.6 0.019 15.2 0.4 1.3 1 1 0 1 1 1 0 Dehydrin OB_NTP_bind PF07717.11 EKG16689.1 - 6.8e-27 93.5 0.0 1.6e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKG16689.1 - 8.4e-26 89.9 0.2 2.5e-25 88.4 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKG16689.1 - 2e-12 46.7 0.0 5.2e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EKG16689.1 - 5.9e-11 42.2 0.3 1.2e-10 41.3 0.2 1.4 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.1 EKG16689.1 - 1.8e-05 24.9 0.2 9.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EKG16689.1 - 3.6e-05 23.3 0.1 9.3e-05 21.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EKG16689.1 - 6.7e-05 21.9 0.1 0.00023 20.1 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EKG16689.1 - 0.0014 18.2 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EKG16689.1 - 0.0023 18.2 0.1 0.69 10.1 0.0 2.8 1 1 1 2 2 2 1 ABC transporter AAA_14 PF13173.1 EKG16689.1 - 0.0093 15.8 0.1 0.085 12.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EKG16689.1 - 0.0095 15.7 0.2 6.2 6.6 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EKG16689.1 - 0.069 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 EKG16689.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 EKG16689.1 - 0.13 12.0 0.1 0.33 10.7 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 EKG16689.1 - 0.14 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Na_Ca_ex PF01699.19 EKG16691.1 - 1.3e-41 141.4 27.9 4.6e-21 74.9 7.8 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF2207 PF09972.4 EKG16691.1 - 1.1 7.7 0.0 1.1 7.7 0.0 2.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SNF2_N PF00176.18 EKG16692.1 - 7.7e-61 205.4 0.5 3.3e-60 203.4 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG16692.1 - 3.3e-09 36.4 0.0 8.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EKG16692.1 - 0.0002 20.9 12.4 0.00042 19.9 8.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG16692.1 - 0.00046 20.1 12.1 0.00092 19.1 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EKG16692.1 - 0.0059 16.4 1.2 0.011 15.5 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EKG16692.1 - 0.011 15.4 10.4 0.021 14.5 7.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG16692.1 - 0.046 13.4 4.9 0.14 11.9 3.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 EKG16692.1 - 0.087 12.6 12.5 0.18 11.6 8.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EKG16692.1 - 0.1 12.2 13.1 0.21 11.2 9.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKG16692.1 - 4.4 7.2 11.3 9.5 6.1 7.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Fungal_trans PF04082.13 EKG16693.1 - 3.9e-43 147.1 0.0 7.5e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAT1 PF09770.4 EKG16693.1 - 7.6 4.6 9.2 12 4.0 6.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_72 PF03198.9 EKG16694.1 - 3.5e-121 404.0 3.9 4.6e-121 403.6 2.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EKG16694.1 - 1.6e-07 30.5 0.1 4.8e-07 28.9 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EKG16694.1 - 0.00033 19.9 0.1 0.0042 16.3 0.1 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CDK2AP PF09806.4 EKG16694.1 - 0.13 12.4 4.2 0.33 11.1 2.9 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein ADH_zinc_N PF00107.21 EKG16695.1 - 3.3e-29 101.0 0.5 5.9e-29 100.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG16695.1 - 7.6e-16 59.1 0.0 1.7e-15 58.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG16695.1 - 4.4e-09 36.0 0.0 6.8e-08 32.2 0.0 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Tautomerase_3 PF14832.1 EKG16696.1 - 8.4e-10 38.7 0.0 2.1e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EKG16696.1 - 0.0072 15.9 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Tautomerase enzyme NUC153 PF08159.7 EKG16697.1 - 8.7e-15 54.0 0.2 3.3e-14 52.1 0.2 2.1 1 0 0 1 1 1 1 NUC153 domain ATP-synt_J PF04911.7 EKG16697.1 - 0.2 11.1 0.9 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase j chain Pyr_redox_2 PF07992.9 EKG16698.1 - 1.9e-17 63.7 0.0 3.2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG16698.1 - 6.6e-11 42.4 0.0 1.4e-09 38.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 EKG16698.1 - 1.7e-08 34.4 1.0 0.00012 22.1 0.1 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EKG16698.1 - 9.4e-07 27.7 0.0 3.6e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EKG16698.1 - 2.3e-06 27.0 0.3 8.9e-06 25.1 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EKG16698.1 - 1.8e-05 23.8 0.7 4.3e-05 22.6 0.5 1.7 1 0 0 1 1 1 1 EF hand Adaptin_N PF01602.15 EKG16700.1 - 4.3e-101 338.8 0.0 6.5e-101 338.2 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EKG16700.1 - 1.2e-10 41.4 9.0 5.3e-05 23.4 0.0 4.6 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EKG16700.1 - 2e-08 33.5 0.5 0.22 11.6 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EKG16700.1 - 3.4e-06 27.3 10.1 0.018 15.5 0.0 5.4 5 0 0 5 5 5 2 HEAT-like repeat RasGEF_N_2 PF14663.1 EKG16700.1 - 0.0035 17.2 0.4 0.3 11.0 0.0 3.6 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.2 EKG16700.1 - 0.0044 16.9 0.0 0.39 10.7 0.0 3.1 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EKG16700.1 - 0.011 15.6 0.0 0.93 9.3 0.0 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 VHS PF00790.14 EKG16700.1 - 0.043 13.4 0.2 2.7 7.6 0.0 3.0 3 0 0 3 3 3 0 VHS domain Arm PF00514.18 EKG16700.1 - 0.53 10.1 6.3 13 5.7 0.1 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Nop14 PF04147.7 EKG16700.1 - 4.6 5.0 26.1 1.1 7.0 15.6 1.7 2 0 0 2 2 2 0 Nop14-like family NTPase_P4 PF11602.3 EKG16702.1 - 0.067 12.1 0.1 0.071 12.0 0.1 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 HD_4 PF13328.1 EKG16702.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 HD domain Metallophos PF00149.23 EKG16703.1 - 1.8e-41 141.7 0.8 2.3e-41 141.4 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CLTH PF10607.4 EKG16704.1 - 1.7e-35 121.8 0.1 2.1e-35 121.5 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EKG16704.1 - 2e-05 24.2 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 LisH PRK PF00485.13 EKG16705.1 - 5.7e-60 202.2 0.0 7.7e-60 201.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EKG16705.1 - 2.4e-36 124.8 0.0 3.7e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EKG16705.1 - 4.3e-08 34.0 0.0 1.1e-07 32.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EKG16705.1 - 8.1e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EKG16705.1 - 0.0013 19.0 0.1 0.0043 17.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG16705.1 - 0.01 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EKG16705.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EKG16705.1 - 0.026 14.2 0.0 0.084 12.6 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EKG16705.1 - 0.026 13.9 0.1 0.092 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EKG16705.1 - 0.036 12.9 0.1 0.083 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.18 EKG16705.1 - 0.039 13.3 0.1 0.11 11.9 0.1 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pribosyltran PF00156.22 EKG16705.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase domain AAA_29 PF13555.1 EKG16705.1 - 0.054 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EKG16705.1 - 0.058 13.6 0.2 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 ABC transporter Lambda_tail_I PF06805.7 EKG16705.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I MobB PF03205.9 EKG16705.1 - 0.082 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EKG16705.1 - 0.12 12.1 0.0 1.3 8.7 0.0 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MFS_1 PF07690.11 EKG16706.1 - 1.7e-48 165.1 54.1 5.4e-38 130.6 16.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EKG16706.1 - 8.1e-07 28.0 4.0 1.6e-06 27.1 0.3 2.1 2 0 0 2 2 2 1 BT1 family MFS_1_like PF12832.2 EKG16706.1 - 6.9e-05 22.5 6.4 0.04 13.7 0.0 3.6 3 1 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 EKG16706.1 - 0.00026 19.5 26.3 0.033 12.5 5.2 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein FLO_LFY PF01698.11 EKG16707.1 - 3.2 6.5 8.2 5.8 5.6 5.7 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Asp PF00026.18 EKG16708.1 - 4.3e-63 213.4 9.1 5.3e-63 213.1 6.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG16708.1 - 4.3e-06 27.1 3.1 0.0036 17.7 1.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EKG16708.1 - 0.015 15.2 0.0 0.067 13.1 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal DUF221 PF02714.10 EKG16711.1 - 4e-113 377.5 12.9 4e-113 377.5 8.9 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EKG16711.1 - 7.5e-40 136.0 3.1 7.5e-40 136.0 2.2 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EKG16711.1 - 1.3e-29 101.8 0.3 4.4e-28 97.0 0.1 2.4 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EKG16711.1 - 2.6e-17 63.1 0.2 4.7e-17 62.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF1134 PF06577.7 EKG16711.1 - 0.012 15.0 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) RRM_5 PF13893.1 EKG16711.1 - 0.039 13.8 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.21 EKG16712.1 - 1.4e-25 89.3 0.2 1.4e-25 89.3 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG16712.1 - 3.3e-21 75.0 0.1 5.7e-21 74.3 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EKG16712.1 - 0.00044 21.1 0.1 0.00084 20.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG16712.1 - 0.065 12.3 0.2 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FA_desaturase PF00487.19 EKG16713.1 - 0.32 10.4 4.0 0.98 8.8 2.7 1.7 1 1 0 1 1 1 0 Fatty acid desaturase DUF3357 PF11837.3 EKG16713.1 - 3.3 7.5 5.7 2 8.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) WD40 PF00400.27 EKG16715.1 - 2.6e-07 30.2 0.3 0.00048 19.9 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EKG16715.1 - 0.00015 21.1 0.2 0.24 10.9 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.17 EKG16715.1 - 0.0025 17.3 0.0 0.23 10.8 0.0 2.4 2 0 0 2 2 2 2 CNH domain Coatomer_WDAD PF04053.9 EKG16715.1 - 0.051 12.3 0.0 0.31 9.7 0.0 2.2 3 0 0 3 3 3 0 Coatomer WD associated region Cupin_8 PF13621.1 EKG16717.1 - 5.5e-34 117.7 0.0 6.4e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EKG16717.1 - 5.1e-09 35.8 0.0 1.4e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 Cupin superfamily protein DSPc PF00782.15 EKG16718.1 - 1.3e-28 99.2 0.0 8.8e-21 73.8 0.0 2.9 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKG16718.1 - 1.2e-05 24.7 0.0 0.00022 20.6 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Clp1 PF06807.9 EKG16722.1 - 3.6e-21 75.8 0.0 5.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EKG16722.1 - 4.5e-10 39.3 0.0 1.4e-09 37.8 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EKG16722.1 - 6.5e-06 25.8 0.0 6.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EKG16722.1 - 1.1e-05 25.3 0.0 7.6e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EKG16722.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 EKG16722.1 - 0.0089 15.3 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_10 PF12846.2 EKG16722.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 EKG16722.1 - 0.016 14.4 0.0 0.074 12.2 0.0 2.1 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKG16722.1 - 0.021 14.3 0.0 0.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EKG16722.1 - 0.034 13.9 0.0 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_35 PF14516.1 EKG16722.1 - 0.064 11.8 0.0 0.097 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 EKG16722.1 - 0.071 12.3 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRP54 PF00448.17 EKG16722.1 - 0.15 11.5 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arb1 PF09692.5 EKG16724.1 - 2.8e-119 398.5 0.3 3.6e-119 398.1 0.2 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 La PF05383.12 EKG16724.1 - 9.3e-15 54.1 0.0 1.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 La domain Aldo_ket_red PF00248.16 EKG16727.1 - 2.2e-69 233.4 0.0 2.5e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ion_trans PF00520.26 EKG16729.1 - 5e-07 29.1 20.7 1.4e-06 27.6 14.3 1.8 1 1 0 1 1 1 1 Ion transport protein CPSase_L_D2 PF02786.12 EKG16730.1 - 8.9e-114 378.0 0.2 2.2e-83 278.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EKG16730.1 - 1e-44 152.2 0.0 2.7e-44 150.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EKG16730.1 - 4.2e-44 149.2 0.0 1.1e-43 147.8 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EKG16730.1 - 3.7e-43 146.5 0.0 7.9e-43 145.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EKG16730.1 - 4.6e-42 142.5 0.0 1.6e-20 73.2 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EKG16730.1 - 2.3e-41 140.3 0.0 6.5e-41 138.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EKG16730.1 - 2e-37 128.6 0.1 1.9e-22 79.8 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 EKG16730.1 - 5.6e-35 120.5 0.0 1.2e-34 119.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EKG16730.1 - 1.3e-23 83.3 0.3 2.5e-11 42.9 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EKG16730.1 - 1.6e-19 69.5 0.0 1.6e-18 66.4 0.0 2.9 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EKG16730.1 - 9.1e-17 61.1 0.4 3.7e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EKG16730.1 - 9.7e-17 60.8 0.0 4.2e-08 32.7 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EKG16730.1 - 6.6e-08 32.2 0.0 7.6e-06 25.5 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EKG16730.1 - 1.4e-06 28.2 0.5 0.031 14.1 0.0 2.8 3 0 0 3 3 2 2 ATP-grasp domain RimK PF08443.6 EKG16730.1 - 2.6e-06 27.0 0.0 0.00058 19.3 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EKG16730.1 - 0.0013 18.3 0.3 1.5 8.3 0.0 2.7 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 EKG16730.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Synaptobrevin PF00957.16 EKG16731.1 - 8.7e-33 111.7 0.0 1.2e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EKG16731.1 - 7.1e-24 83.1 0.0 1.1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF2628 PF10947.3 EKG16731.1 - 0.068 12.9 1.4 0.13 12.0 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) FGase PF05013.7 EKG16731.1 - 0.099 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase TBP-binding PF09247.6 EKG16733.1 - 0.057 13.6 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 TATA box-binding protein binding Glyco_hydro_53 PF07745.8 EKG16734.1 - 3.7e-71 239.6 0.0 4.6e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Sec7 PF01369.15 EKG16735.1 - 1.7e-64 216.9 0.0 2.9e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EKG16735.1 - 1.1e-22 80.3 0.1 1.4e-14 53.9 0.2 3.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Anp1 PF03452.9 EKG16736.1 - 3.6e-120 400.1 0.4 6.9e-120 399.2 0.0 1.6 2 0 0 2 2 2 1 Anp1 DUF1675 PF07897.6 EKG16736.1 - 0.00013 21.9 17.4 0.00019 21.3 12.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1675) Glyco_tranf_2_4 PF13704.1 EKG16736.1 - 0.031 14.6 0.1 0.12 12.6 0.0 2.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 Macoilin PF09726.4 EKG16736.1 - 0.87 7.7 19.4 1.2 7.3 13.4 1.1 1 0 0 1 1 1 0 Transmembrane protein CCDC71L PF15374.1 EKG16736.1 - 1.6 7.9 20.8 2.9 7.0 14.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L PLRV_ORF5 PF01690.12 EKG16736.1 - 4.5 6.3 24.9 6 5.8 17.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_delta_4 PF04081.8 EKG16737.1 - 8.8e-28 97.0 1.7 1.1e-27 96.7 0.8 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DcpS_C PF11969.3 EKG16738.1 - 6.4e-32 110.1 0.3 1.4e-31 109.1 0.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EKG16738.1 - 4.1e-29 101.2 0.0 7e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Hamartin PF04388.7 EKG16739.1 - 1e-43 150.0 8.8 1.5e-43 149.5 5.4 1.6 1 1 0 1 1 1 1 Hamartin protein DUF2811 PF10929.3 EKG16739.1 - 0.054 13.5 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) TAP42 PF04177.7 EKG16740.1 - 3.4e-108 361.6 0.2 3.8e-108 361.4 0.1 1.0 1 0 0 1 1 1 1 TAP42-like family Ribonuclease_3 PF00636.21 EKG16741.1 - 1e-40 138.7 0.0 2.3e-19 69.8 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EKG16741.1 - 1.7e-25 89.4 0.0 2.7e-11 43.5 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EKG16741.1 - 1.6e-20 72.6 0.8 1.5e-19 69.5 0.0 3.0 4 0 0 4 4 4 1 Dicer dimerisation domain Helicase_C PF00271.26 EKG16741.1 - 4.4e-15 55.3 0.0 9.5e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG16741.1 - 6.4e-11 42.0 0.0 1.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EKG16741.1 - 1.2e-09 38.3 0.0 2e-07 31.0 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EKG16741.1 - 0.018 14.0 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EKG16741.1 - 0.024 13.4 1.4 0.3 9.8 0.1 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain Solute_trans_a PF03619.11 EKG16742.1 - 6.9e-56 189.5 11.0 8.3e-56 189.3 7.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Orbi_NS3 PF01616.11 EKG16742.1 - 0.56 9.1 2.1 3.7 6.4 1.6 1.9 2 0 0 2 2 2 0 Orbivirus NS3 Glyco_transf_15 PF01793.11 EKG16744.1 - 1.6e-140 467.7 7.4 2e-140 467.4 5.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase FtsH_ext PF06480.10 EKG16744.1 - 0.045 13.9 4.8 1.6 8.9 3.3 2.5 1 1 0 1 1 1 0 FtsH Extracellular PAT1 PF09770.4 EKG16745.1 - 1.2e-254 847.3 12.2 1.4e-254 847.2 8.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 LRR_9 PF14580.1 EKG16747.1 - 3.2e-46 157.1 0.1 6.1e-46 156.1 0.0 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EKG16747.1 - 6.8e-11 41.5 1.7 2.7e-08 33.2 0.2 4.0 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG16747.1 - 3.3e-09 36.3 0.6 4.1e-08 32.8 0.1 2.9 3 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EKG16747.1 - 8.8e-06 25.0 1.8 9.2 6.7 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EKG16747.1 - 0.0031 17.4 2.8 7.7 7.1 0.1 4.9 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EKG16747.1 - 0.095 12.8 2.0 5.3 7.4 0.1 3.9 6 0 0 6 6 6 0 Leucine Rich repeat Peptidase_C48 PF02902.14 EKG16748.1 - 7.7e-19 68.1 0.0 1.8e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Methyltransf_1N PF02870.10 EKG16748.1 - 0.23 12.0 2.6 0.34 11.5 0.0 2.6 3 0 0 3 3 3 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Pkinase PF00069.20 EKG16749.1 - 1.2e-25 90.2 0.0 1.8e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EKG16749.1 - 4.4e-16 58.0 4.2 3.8e-08 32.8 0.1 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 EKG16749.1 - 5.5e-11 41.5 6.4 0.024 14.6 0.2 7.1 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 EKG16749.1 - 4.6e-06 25.9 0.0 7.6e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EKG16749.1 - 5.6e-06 26.5 8.7 0.053 13.8 0.0 4.4 2 1 2 4 4 4 4 HEAT repeats HEAT_EZ PF13513.1 EKG16749.1 - 1e-05 25.8 4.7 0.0026 18.1 1.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.15 EKG16749.1 - 0.003 15.9 0.8 0.014 13.7 0.0 2.0 2 0 0 2 2 2 1 Adaptin N terminal region Kinase-like PF14531.1 EKG16749.1 - 0.007 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CLASP_N PF12348.3 EKG16749.1 - 0.05 12.9 0.6 0.51 9.6 0.2 2.3 2 0 0 2 2 2 0 CLASP N terminal Glycos_transf_1 PF00534.15 EKG16750.1 - 1.8e-30 105.6 0.0 4.5e-29 101.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EKG16750.1 - 4e-08 33.5 0.0 1.2e-07 31.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EKG16750.1 - 2.2e-06 27.8 0.0 7e-05 22.9 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EKG16750.1 - 3.6e-06 26.8 0.0 4.6e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EKG16750.1 - 3.5e-05 23.9 0.0 7.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 OTU PF02338.14 EKG16752.1 - 5.5e-18 65.6 0.2 2.5e-17 63.5 0.1 2.0 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 EKG16752.1 - 0.00038 19.8 0.1 0.00091 18.6 0.0 1.6 2 0 0 2 2 2 1 CUE domain Peptidase_C65 PF10275.4 EKG16752.1 - 0.0026 17.1 0.1 0.34 10.2 0.0 2.6 1 1 0 2 2 2 2 Peptidase C65 Otubain DUF3043 PF11241.3 EKG16752.1 - 0.031 13.8 3.3 0.086 12.4 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DAO PF01266.19 EKG16753.1 - 6.2e-26 91.1 1.4 2.2e-25 89.3 1.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG16753.1 - 0.0013 18.6 0.0 0.0049 16.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG16753.1 - 0.008 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG16753.1 - 0.0082 15.2 0.6 0.017 14.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 EKG16753.1 - 0.029 13.8 0.7 0.13 11.6 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EKG16753.1 - 0.03 14.7 0.0 0.072 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EKG16753.1 - 0.076 11.9 0.9 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Pyr_redox_3 PF13738.1 EKG16753.1 - 0.081 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EKG16753.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.5 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EKG16753.1 - 0.098 12.0 0.2 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EKG16754.1 - 2.3e-07 30.6 0.0 4.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.9 EKG16755.1 - 2.2e-39 134.5 0.0 4.5e-37 126.9 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.8 EKG16755.1 - 0.015 14.2 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain MMPL PF03176.10 EKG16757.1 - 0.014 14.1 1.9 0.015 14.0 1.3 1.0 1 0 0 1 1 1 0 MMPL family NARP1 PF12569.3 EKG16757.1 - 4.7 5.8 8.9 5.8 5.5 6.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-C2H2_4 PF13894.1 EKG16760.1 - 6 7.4 7.8 11 6.6 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2890 PF11081.3 EKG16762.1 - 0.19 11.7 6.3 0.27 11.2 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 EKG16762.1 - 3.8 5.2 8.0 4.5 5.0 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EKG16762.1 - 6.2 6.0 8.9 6.8 5.8 6.2 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 EKG16762.1 - 8.3 5.9 12.1 15 5.1 8.4 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region COesterase PF00135.23 EKG16763.1 - 6.5e-84 282.5 0.0 7.3e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG16763.1 - 1.6e-08 34.3 0.1 4.4e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG16763.1 - 1.2e-05 24.6 0.1 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG16763.1 - 0.0034 17.1 0.1 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EKG16765.1 - 7.9e-25 87.2 31.7 2.7e-24 85.5 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Vma12 PF11712.3 EKG16765.1 - 0.058 13.1 0.0 0.23 11.1 0.0 2.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF486 PF04342.7 EKG16765.1 - 0.22 11.5 4.3 0.17 11.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF486 Fungal_trans PF04082.13 EKG16766.1 - 4.7e-12 45.3 0.1 8e-12 44.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1479 PF07350.7 EKG16767.1 - 1.6e-07 30.2 0.0 0.046 12.2 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) PhyH PF05721.8 EKG16767.1 - 0.017 15.1 0.0 6.8 6.6 0.0 2.5 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) FAD_binding_3 PF01494.14 EKG16768.1 - 2.8e-19 69.4 0.9 1.9e-18 66.6 0.6 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG16768.1 - 4.6e-06 25.7 8.5 6.2e-05 22.0 0.1 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EKG16768.1 - 4.9e-05 22.1 0.5 0.21 10.2 0.2 2.7 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EKG16768.1 - 0.00013 21.9 0.7 0.00055 19.9 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG16768.1 - 0.00073 19.4 0.7 0.0043 16.9 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG16768.1 - 0.00082 18.3 1.0 0.2 10.5 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EKG16768.1 - 0.00089 18.8 0.5 0.0064 16.0 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EKG16768.1 - 0.0012 17.7 2.1 0.0013 17.6 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EKG16768.1 - 0.0032 17.8 0.1 0.0096 16.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG16768.1 - 0.0058 16.4 4.0 0.65 9.7 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding SE PF08491.5 EKG16768.1 - 0.0079 15.0 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase HI0933_like PF03486.9 EKG16768.1 - 0.028 12.9 0.3 0.07 11.5 0.1 1.7 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EKG16768.1 - 0.079 12.0 0.1 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Rav1p_C PF12234.3 EKG16770.1 - 1.7e-265 882.1 0.0 4.7e-265 880.6 0.0 1.7 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 EKG16770.1 - 5.9e-05 22.7 0.8 2.6 8.0 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Methyltransf_31 PF13847.1 EKG16771.1 - 1.6e-14 53.7 0.0 3e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG16771.1 - 1.6e-11 43.9 0.0 3.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EKG16771.1 - 3.4e-11 43.6 0.0 9.6e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG16771.1 - 4.2e-10 39.9 0.1 1.5e-09 38.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG16771.1 - 2.7e-08 33.8 0.0 5.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG16771.1 - 2.5e-07 30.2 0.3 4.2e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EKG16771.1 - 1.7e-06 27.8 0.0 4.5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG16771.1 - 2.6e-06 27.7 0.1 8.2e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.15 EKG16771.1 - 6.1e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 EKG16771.1 - 0.0001 21.4 0.0 0.00023 20.2 0.0 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.13 EKG16771.1 - 0.00015 20.9 0.1 0.00028 20.0 0.1 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EKG16771.1 - 0.00077 18.9 0.1 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EKG16771.1 - 0.0012 18.8 0.2 0.0046 16.9 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EKG16771.1 - 0.0021 16.8 0.0 0.004 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EKG16771.1 - 0.0028 18.1 0.0 0.0077 16.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EKG16771.1 - 0.0047 17.7 0.1 0.56 11.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EKG16771.1 - 0.0059 16.2 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.9 EKG16771.1 - 0.0075 15.4 0.1 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.11 EKG16771.1 - 0.0076 15.8 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 EKG16771.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C2H2_2 PF12756.2 EKG16771.1 - 0.034 14.2 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 1 0 C2H2 type zinc-finger (2 copies) MetW PF07021.7 EKG16771.1 - 0.056 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EKG16771.1 - 0.1 12.2 0.3 0.21 11.2 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain CDI PF02234.14 EKG16771.1 - 0.29 10.9 2.8 0.35 10.7 0.1 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor GrpE PF01025.14 EKG16771.1 - 0.33 10.4 2.8 0.62 9.5 1.6 1.6 2 0 0 2 2 2 0 GrpE DUF3367 PF11847.3 EKG16772.1 - 0.3 8.9 1.6 0.4 8.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) MFS_1 PF07690.11 EKG16774.1 - 4.8e-27 94.5 23.0 4.8e-27 94.5 15.9 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16774.1 - 4.4e-08 32.1 4.8 4.4e-08 32.1 3.4 3.3 2 1 0 3 3 3 1 Sugar (and other) transporter YcfA PF07927.7 EKG16774.1 - 0.091 12.6 0.5 0.19 11.6 0.3 1.4 1 0 0 1 1 1 0 YcfA-like protein RabGAP-TBC PF00566.13 EKG16777.1 - 3.6e-49 167.1 0.0 7.7e-49 166.0 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IncA PF04156.9 EKG16777.1 - 0.0036 16.9 19.6 0.15 11.6 1.2 3.2 3 0 0 3 3 3 2 IncA protein Fib_alpha PF08702.5 EKG16777.1 - 0.85 9.7 17.3 0.99 9.5 4.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.6 EKG16777.1 - 1.5 8.5 10.9 6.7 6.4 1.3 3.0 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Phage_GP20 PF06810.6 EKG16777.1 - 8.1 5.8 9.6 2 7.8 2.6 2.4 2 1 0 2 2 2 0 Phage minor structural protein GP20 DUF1675 PF07897.6 EKG16788.1 - 0.07 13.0 0.7 0.1 12.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RNA_pol_3_Rpc31 PF11705.3 EKG16788.1 - 0.23 11.3 8.4 1.2 8.9 5.6 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nucleoplasmin PF03066.10 EKG16788.1 - 0.58 9.6 5.4 1.1 8.7 3.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 EKG16788.1 - 0.62 9.9 9.0 0.85 9.4 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Git3 PF11710.3 EKG16790.1 - 1.2e-23 83.7 10.0 1.9e-23 83.1 6.9 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EKG16790.1 - 8.3e-13 48.0 0.0 1.2e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EKG16790.1 - 5.9e-10 38.5 9.5 4.6e-06 25.7 6.6 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3_C PF11970.3 EKG16790.1 - 1.4e-05 24.7 0.6 0.0011 18.6 0.0 2.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term H_PPase PF03030.11 EKG16790.1 - 0.013 13.8 0.3 0.023 12.9 0.2 1.3 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DUF605 PF04652.11 EKG16790.1 - 7.3 5.8 18.2 9.8 5.4 12.6 1.1 1 0 0 1 1 1 0 Vta1 like DEAD PF00270.24 EKG16791.1 - 1.2e-35 122.5 0.0 5.8e-35 120.2 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EKG16791.1 - 3e-20 71.5 0.0 5.5e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EKG16791.1 - 7e-20 70.6 0.0 1.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG16791.1 - 0.015 15.0 4.2 0.033 14.0 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DDHD PF02862.12 EKG16791.1 - 5.7 6.6 8.2 10 5.8 5.7 1.4 1 0 0 1 1 1 0 DDHD domain CTP_transf_1 PF01148.15 EKG16792.1 - 2e-16 60.4 7.3 1.3e-13 51.1 2.4 2.0 1 1 1 2 2 2 2 Cytidylyltransferase family WBP-1 PF11669.3 EKG16794.1 - 0.0034 17.4 0.2 0.0059 16.6 0.1 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 GP46 PF07409.7 EKG16794.1 - 0.075 12.3 1.8 0.18 11.1 1.3 1.6 1 0 0 1 1 1 0 Phage protein GP46 DUF2681 PF10883.3 EKG16794.1 - 0.23 11.7 5.4 0.47 10.6 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) p450 PF00067.17 EKG16795.1 - 6.8e-29 100.6 0.0 1.9e-20 72.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 CENP-B_dimeris PF09026.5 EKG16798.1 - 4.2 7.6 10.0 8.6 6.6 6.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SH3_1 PF00018.23 EKG16800.1 - 1.3e-05 24.4 0.0 3.4e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG16800.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain bZIP_1 PF00170.16 EKG16802.1 - 0.00054 19.8 13.1 0.0018 18.2 7.6 2.1 1 1 1 2 2 2 1 bZIP transcription factor DUF4349 PF14257.1 EKG16802.1 - 0.011 15.0 2.3 0.011 15.0 1.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF2956 PF11169.3 EKG16802.1 - 0.15 12.0 3.6 0.19 11.6 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF2937 PF11157.3 EKG16802.1 - 0.3 10.4 3.5 0.42 9.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) BMFP PF04380.8 EKG16802.1 - 0.72 10.0 7.4 0.16 12.1 2.4 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity DUF883 PF05957.8 EKG16802.1 - 1.5 9.2 6.3 3 8.3 4.4 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Mnd1 PF03962.10 EKG16802.1 - 1.6 8.3 6.7 2.2 7.9 4.6 1.1 1 0 0 1 1 1 0 Mnd1 family Metal_resist PF13801.1 EKG16802.1 - 2.6 8.0 12.5 4.2 7.3 8.7 1.4 1 1 0 1 1 1 0 Heavy-metal resistance DUF3425 PF11905.3 EKG16803.1 - 3.7e-30 104.5 1.1 5.8e-30 103.9 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) CytochromB561_N PF09786.4 EKG16804.1 - 1.9 6.8 32.2 2.8 6.3 22.3 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF824 PF05688.6 EKG16804.1 - 1.9 8.2 9.3 11 5.7 0.4 3.4 2 1 1 3 3 3 0 Salmonella repeat of unknown function (DUF824) RhoGAP PF00620.22 EKG16805.1 - 6.8e-39 132.9 0.0 1.1e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.10 EKG16806.1 - 3.9e-20 70.8 2.6 4.9e-20 70.5 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EKG16806.1 - 0.031 13.7 2.9 0.071 12.5 2.0 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) polyprenyl_synt PF00348.12 EKG16807.1 - 3.1e-56 190.1 0.0 3.7e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase S1 PF00575.18 EKG16808.1 - 5.2e-80 263.5 45.9 8.5e-14 51.4 2.4 13.3 13 0 0 13 13 13 12 S1 RNA binding domain Suf PF05843.9 EKG16808.1 - 2e-06 27.7 2.4 0.0044 16.8 0.0 4.5 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EKG16808.1 - 6.3e-06 26.3 0.6 1.1 10.0 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG16808.1 - 1.3e-05 25.4 0.0 0.21 11.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_3 PF13812.1 EKG16808.1 - 0.034 14.4 0.1 24 5.5 0.0 4.0 3 0 0 3 3 3 0 Pentatricopeptide repeat domain WD40 PF00400.27 EKG16809.1 - 1.9e-25 87.7 8.2 3.2e-08 33.1 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EKG16809.1 - 0.019 13.1 0.3 0.069 11.2 0.2 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 HET PF06985.6 EKG16810.1 - 9.3e-22 77.6 0.1 2.1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sulfatase PF00884.18 EKG16811.1 - 1.3e-30 106.6 1.0 1.1e-29 103.6 0.0 1.9 1 1 1 2 2 2 1 Sulfatase DUF229 PF02995.12 EKG16811.1 - 0.03 12.7 0.4 0.21 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EKG16811.1 - 0.04 13.2 1.1 0.074 12.3 0.8 1.7 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2779 PF11074.3 EKG16811.1 - 0.064 13.3 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) DUF1501 PF07394.7 EKG16811.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF1237 PF06824.6 EKG16812.1 - 4e-181 602.2 0.0 5.4e-181 601.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Fungal_trans PF04082.13 EKG16812.1 - 2.8e-18 65.7 0.6 5.7e-18 64.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG16812.1 - 5.7e-08 32.5 9.7 9.6e-08 31.8 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 EKG16812.1 - 0.41 10.9 2.5 0.94 9.7 1.7 1.5 1 0 0 1 1 1 0 Striatin family Fungal_trans PF04082.13 EKG16813.1 - 1.5e-21 76.4 0.0 2.5e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VPS9 PF02204.13 EKG16814.1 - 2.4e-17 62.8 0.0 4.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EKG16814.1 - 2.3e-09 36.5 0.1 6.9e-08 31.8 0.0 2.6 2 0 0 2 2 2 1 CUE domain Cytochrom_C PF00034.16 EKG16814.1 - 1.2 9.9 6.4 0.75 10.6 1.8 2.7 2 0 0 2 2 2 0 Cytochrome c Borrelia_P83 PF05262.6 EKG16814.1 - 3 6.0 9.5 4.7 5.3 6.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Asn_synthase PF00733.16 EKG16815.1 - 3e-52 177.6 0.0 4e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EKG16815.1 - 1e-07 31.7 0.0 5.1e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EKG16815.1 - 3e-05 23.9 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EKG16815.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein Glyco_hydro_16 PF00722.16 EKG16816.1 - 2.5e-42 144.2 7.5 3.8e-42 143.6 5.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WHEP-TRS PF00458.15 EKG16816.1 - 0.011 15.4 0.2 0.21 11.2 0.2 2.4 2 0 0 2 2 2 0 WHEP-TRS domain IncA PF04156.9 EKG16816.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein Syja_N PF02383.13 EKG16817.1 - 1.5e-91 306.4 0.1 3e-91 305.5 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain MMS1_N PF10433.4 EKG16818.1 - 3e-86 289.5 0.0 5.1e-86 288.8 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EKG16818.1 - 2.1e-69 234.1 0.0 1.1e-67 228.4 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region AIG2 PF06094.7 EKG16818.1 - 0.12 12.8 0.1 1.3 9.5 0.0 2.9 3 0 0 3 3 3 0 AIG2-like family Sin_N PF04801.8 EKG16819.1 - 7.2e-17 61.3 4.2 3.7e-16 59.0 2.9 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region NAD_binding_2 PF03446.10 EKG16820.1 - 3.1e-37 127.9 1.6 1.6e-36 125.6 0.0 2.6 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EKG16820.1 - 3.7e-26 91.5 0.0 2.1e-25 89.1 0.0 2.3 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Snf7 PF03357.16 EKG16820.1 - 5.1e-14 52.0 2.1 8.5e-14 51.2 1.4 1.3 1 0 0 1 1 1 1 Snf7 OCD_Mu_crystall PF02423.10 EKG16820.1 - 1.1e-07 30.9 3.9 1.4e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EKG16820.1 - 1.1e-05 25.7 1.1 3.8e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EKG16820.1 - 0.0023 18.4 0.0 0.0079 16.7 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EKG16820.1 - 0.0043 16.2 0.0 0.011 14.8 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-RING_5 PF14634.1 EKG16821.1 - 7.3e-07 28.8 12.4 7.3e-07 28.8 8.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EKG16821.1 - 1.2e-06 28.0 12.0 1.2e-06 28.0 8.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG16821.1 - 3.1e-06 27.1 12.8 3.1e-06 27.1 8.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EKG16821.1 - 4.1e-06 26.4 3.5 8.5e-06 25.4 2.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EKG16821.1 - 1.6e-05 24.4 10.1 1.6e-05 24.4 7.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 EKG16821.1 - 3.2e-05 23.3 0.0 6.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.1 EKG16821.1 - 5.2e-05 22.9 12.9 5.2e-05 22.9 9.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EKG16821.1 - 0.00014 21.6 11.7 0.00014 21.6 8.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EKG16821.1 - 0.00023 20.8 6.6 0.00023 20.8 4.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Sec23_helical PF04815.10 EKG16821.1 - 0.073 12.5 0.6 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Mob_synth_C PF06463.8 EKG16821.1 - 0.14 11.8 5.6 0.39 10.3 3.9 1.8 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-rbx1 PF12678.2 EKG16821.1 - 0.47 10.6 10.4 0.15 12.2 4.3 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EKG16821.1 - 0.76 9.4 14.7 0.51 9.9 7.6 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Voltage_CLC PF00654.15 EKG16822.1 - 3.9e-92 308.9 22.0 3.9e-92 308.9 15.3 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EKG16822.1 - 7.2e-14 51.3 0.1 3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 EKG16823.1 - 2.9e-13 49.6 1.0 2.9e-13 49.6 0.7 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ground-like PF04155.13 EKG16823.1 - 0.016 15.5 0.2 0.016 15.5 0.1 1.7 2 0 0 2 2 2 0 Ground-like domain Histone PF00125.19 EKG16823.1 - 0.027 14.5 0.4 0.027 14.5 0.3 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Peroxidase_2 PF01328.12 EKG16824.1 - 2.6e-14 52.6 1.7 4.7e-14 51.7 0.4 1.9 2 1 0 2 2 2 1 Peroxidase, family 2 Abhydrolase_3 PF07859.8 EKG16825.1 - 2.3e-39 135.1 0.3 3.2e-39 134.6 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EKG16825.1 - 1.6e-06 27.5 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EKG16825.1 - 0.00015 21.1 0.0 0.00038 19.7 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EKG16825.1 - 0.00048 19.6 0.0 0.28 10.5 0.0 2.3 2 1 0 2 2 2 2 Putative esterase Abhydrolase_5 PF12695.2 EKG16825.1 - 0.00062 19.5 0.1 0.00082 19.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG16825.1 - 0.0012 18.7 7.7 0.0019 18.1 5.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EKG16825.1 - 0.036 13.4 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EKG16825.1 - 0.21 10.0 0.2 3.5 6.0 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) K_channel_TID PF07941.6 EKG16826.1 - 0.011 15.9 10.2 0.011 15.9 7.0 2.2 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain LZ_Tnp_IS66 PF13007.2 EKG16829.1 - 0.0022 18.6 1.2 0.0051 17.4 0.9 1.6 1 0 0 1 1 1 1 Transposase C of IS166 homeodomain Zn_clus PF00172.13 EKG16830.1 - 0.0016 18.2 3.0 0.0016 18.2 2.1 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EKG16830.1 - 0.11 11.0 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain YccV-like PF08755.6 EKG16830.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like Cornifin PF02389.10 EKG16832.1 - 0.0037 17.0 1.3 0.011 15.5 0.9 1.6 1 1 0 1 1 1 1 Cornifin (SPRR) family Aldo_ket_red PF00248.16 EKG16833.1 - 1.7e-41 141.9 0.0 2.1e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4572 PF15139.1 EKG16834.1 - 1 9.1 3.9 1.4 8.6 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) DUF1264 PF06884.6 EKG16835.1 - 7.2e-76 253.3 0.1 8.5e-76 253.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) CorA PF01544.13 EKG16836.1 - 1.5e-26 93.1 3.0 6.2e-23 81.2 1.1 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein zf-MYND PF01753.13 EKG16837.1 - 1.5e-07 31.1 21.2 3.5e-07 29.9 14.7 1.7 1 0 0 1 1 1 1 MYND finger E1-E2_ATPase PF00122.15 EKG16838.1 - 5.9e-19 68.0 0.0 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKG16838.1 - 1e-16 62.0 0.0 1.1e-15 58.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG16838.1 - 4.2e-14 53.1 0.4 4.9e-13 49.6 0.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG16838.1 - 7.2e-11 41.9 0.0 2.6e-10 40.0 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKG16838.1 - 0.00079 19.0 0.1 0.0027 17.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EKG16843.1 - 8.7e-26 90.3 0.1 1.3e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG16843.1 - 7.8e-06 25.7 15.5 1.2e-05 25.0 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 EKG16843.1 - 0.077 13.2 2.8 1.2 9.4 1.9 2.2 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Sugar_tr PF00083.19 EKG16844.1 - 3.4e-80 269.8 22.4 3.7e-80 269.7 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG16844.1 - 4e-26 91.5 32.1 2e-23 82.6 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EKG16846.1 - 2.6e-13 49.6 0.0 4.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG16846.1 - 6.2e-05 23.8 0.0 8.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PBCV_basic_adap PF08789.5 EKG16846.1 - 0.087 12.4 5.0 0.18 11.4 0.5 2.2 2 0 0 2 2 2 0 PBCV-specific basic adaptor domain adh_short PF00106.20 EKG16847.1 - 1.7e-28 99.6 7.7 2.5e-28 99.0 5.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG16847.1 - 1.6e-20 73.9 1.4 2e-20 73.5 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG16847.1 - 3.7e-13 49.5 5.9 7.1e-13 48.6 4.1 1.4 1 1 0 1 1 1 1 KR domain DFP PF04127.10 EKG16847.1 - 0.0017 17.9 1.4 0.0029 17.2 1.0 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Phe_hydrox_dim PF07976.7 EKG16851.1 - 2.8e-32 111.6 0.0 4.6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 EKG16851.1 - 2e-30 106.0 0.0 1.2e-17 63.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 EKG16852.1 - 4.8e-11 42.3 0.0 6.1e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 EKG16853.1 - 8.4e-07 28.1 0.3 1.6e-06 27.2 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4611 PF15387.1 EKG16855.1 - 0.75 9.9 8.8 0.11 12.6 0.3 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4611) DUF1989 PF09347.5 EKG16856.1 - 4.5e-08 32.7 0.0 8.4e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Orthopox_35kD PF02250.10 EKG16856.1 - 0.95 8.7 5.8 0.19 11.0 0.3 2.2 2 1 0 2 2 2 0 35kD major secreted virus protein MmgE_PrpD PF03972.9 EKG16857.1 - 2.3e-74 250.1 3.4 2.7e-74 249.9 2.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Aminotran_1_2 PF00155.16 EKG16858.1 - 4.1e-61 206.9 0.0 5.6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKG16858.1 - 0.013 14.7 0.0 0.025 13.7 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase BH4 PF02180.12 EKG16858.1 - 0.59 9.6 3.1 1.9 8.0 0.4 2.4 2 0 0 2 2 2 0 Bcl-2 homology region 4 TIM PF00121.13 EKG16860.1 - 7.5e-92 306.8 0.2 8.4e-92 306.6 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L51_S25_CI-B8 PF05047.11 EKG16861.1 - 7.3e-15 54.4 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EKG16862.1 - 3.3e-12 46.5 1.5 7e-12 45.5 1.0 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EKG16862.1 - 5.4e-12 45.1 0.1 2.7e-11 42.9 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG16862.1 - 3.6e-09 36.4 0.0 1.4e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG16862.1 - 0.00022 20.9 0.2 0.0025 17.6 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2075 PF09848.4 EKG16862.1 - 0.014 14.3 0.1 0.019 13.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0052 PF01933.13 EKG16863.1 - 9.2e-52 176.2 0.0 1.2e-51 175.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 COMPASS-Shg1 PF05205.7 EKG16865.1 - 2.7e-06 27.6 0.1 6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Pup PF05639.6 EKG16867.1 - 0.59 10.6 2.7 0.85 10.1 0.1 2.5 2 0 0 2 2 2 0 Pup-like protein Translin PF01997.11 EKG16868.1 - 5.6e-51 172.9 0.0 6.6e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 EKG16868.1 - 0.044 13.4 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 GMP synthase C terminal domain PIG-F PF06699.6 EKG16869.1 - 3.9e-54 183.5 5.6 4.9e-54 183.1 3.9 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F RNA_pol_Rpc4 PF05132.9 EKG16870.1 - 8.4e-27 93.7 2.3 3.8e-26 91.6 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase III RPC4 LIN37 PF15306.1 EKG16870.1 - 0.015 15.3 1.7 0.015 15.3 1.2 2.0 2 0 0 2 2 2 0 LIN37 IN_DBD_C PF00552.16 EKG16870.1 - 0.042 13.3 0.4 0.091 12.2 0.2 1.6 1 0 0 1 1 1 0 Integrase DNA binding domain Methyltransf_3 PF01596.12 EKG16872.1 - 1.4e-12 47.0 0.0 1.9e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EKG16872.1 - 3e-11 44.0 0.1 4.6e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG16872.1 - 1.4e-05 25.6 0.1 2.6e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 EKG16873.1 - 1.4e-17 64.2 0.0 4.6e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG16873.1 - 0.0011 18.3 0.0 0.022 14.0 0.0 2.5 3 0 0 3 3 3 1 NmrA-like family Aldo_ket_red PF00248.16 EKG16874.1 - 5.5e-51 173.0 0.0 7.2e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0164 PF03687.8 EKG16874.1 - 0.041 12.4 0.2 0.19 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0164) Apc13p PF05839.6 EKG16876.1 - 1.3e-27 95.5 0.1 1.5e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Apc13p protein DUF4211 PF13926.1 EKG16877.1 - 2.7e-36 124.2 0.0 1.3e-35 122.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) A_deaminase PF00962.17 EKG16878.1 - 9.7e-28 97.0 0.0 1.2e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase WD40 PF00400.27 EKG16879.1 - 3.1e-50 166.3 19.9 2.1e-08 33.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EKG16879.1 - 1.9e-05 24.4 0.0 0.016 14.9 0.0 2.7 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EKG16879.1 - 0.11 10.7 0.0 0.3 9.3 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Phosducin PF02114.11 EKG16880.1 - 2e-13 49.6 0.1 2.2e-12 46.2 0.1 2.2 1 1 0 1 1 1 1 Phosducin NdhO PF11910.3 EKG16880.1 - 0.00042 19.8 0.0 0.00097 18.7 0.0 1.6 1 0 0 1 1 1 1 Cyanobacterial and plant NDH-1 subunit O Pkinase PF00069.20 EKG16882.1 - 1.5e-47 161.9 0.0 2.2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG16882.1 - 1e-26 93.6 0.0 3.3e-26 91.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.18 EKG16883.1 - 4.9e-72 235.5 29.8 2.7e-13 49.1 0.1 11.3 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EKG16883.1 - 5.8e-27 93.7 11.5 9.3e-06 25.8 0.1 7.7 2 2 4 7 7 7 6 HEAT repeats HEAT PF02985.17 EKG16883.1 - 1.3e-22 77.8 14.0 0.016 15.2 0.0 10.0 11 0 0 11 11 11 6 HEAT repeat Adaptin_N PF01602.15 EKG16883.1 - 6.8e-16 57.6 18.3 5.3e-10 38.2 1.8 3.1 1 1 2 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.1 EKG16883.1 - 1.1e-15 57.6 16.1 0.0035 17.7 0.0 8.6 5 3 5 10 10 10 6 HEAT-like repeat KAP PF05804.7 EKG16883.1 - 1.2e-13 49.9 0.2 2.1e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm_2 PF04826.8 EKG16883.1 - 1.4e-12 47.2 5.8 0.0013 17.8 0.1 3.3 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 EKG16883.1 - 2.3e-08 33.5 1.1 0.00022 20.4 0.7 3.3 2 1 1 3 3 3 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EKG16883.1 - 0.026 14.8 0.1 1.2 9.6 0.0 3.2 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EKG16883.1 - 0.034 13.8 1.1 0.28 10.8 0.2 2.7 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 EKG16883.1 - 0.1 13.1 11.4 8.4 7.1 0.6 6.4 7 0 0 7 7 5 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 EKG16883.1 - 0.21 11.3 2.8 7.7 6.3 0.0 4.1 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain MFS_1 PF07690.11 EKG16884.1 - 1.3e-13 50.4 18.1 1.3e-13 50.4 12.5 2.5 3 0 0 3 3 3 1 Major Facilitator Superfamily TRAP_alpha PF03896.11 EKG16885.1 - 2.3e-11 43.2 0.7 1.8e-10 40.2 0.1 2.0 2 0 0 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit ING PF12998.2 EKG16886.1 - 0.0084 16.3 2.4 0.013 15.7 1.3 1.5 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PspA_IM30 PF04012.7 EKG16886.1 - 0.038 13.3 0.3 0.056 12.7 0.2 1.1 1 0 0 1 1 1 0 PspA/IM30 family Peptidase_C98 PF15499.1 EKG16886.1 - 0.069 12.4 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF848 PF05852.6 EKG16886.1 - 0.13 12.0 0.6 0.22 11.3 0.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) zf-CCHH PF10283.4 EKG16887.1 - 1.3 8.8 5.5 1.7 8.5 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif OHCU_decarbox PF09349.5 EKG16888.1 - 1.2e-43 149.1 0.2 1.4e-43 148.8 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase VEK-30 PF12107.3 EKG16888.1 - 0.27 10.9 3.2 0.51 10.1 2.2 1.5 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Ras PF00071.17 EKG16890.1 - 1.4e-31 109.0 0.3 1.8e-31 108.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG16890.1 - 1.8e-20 73.6 0.1 9.4e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKG16890.1 - 1.5e-06 27.5 0.1 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG16890.1 - 1.3e-05 24.4 0.2 1.7e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKG16890.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EKG16890.1 - 0.11 11.1 3.4 0.23 10.1 0.0 2.5 1 1 2 3 3 3 0 G-protein alpha subunit WD40 PF00400.27 EKG16891.1 - 2.9e-21 74.5 7.4 1e-08 34.6 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EKG16891.1 - 4.5e-17 61.7 0.0 1e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3115 PF11312.3 EKG16893.1 - 6.1e-99 330.8 0.0 7.6e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Rsm22 PF09243.5 EKG16893.1 - 0.019 13.9 0.1 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CMD PF02627.15 EKG16894.1 - 1.1e-06 28.4 0.0 8.9e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Pol_alpha_B_N PF08418.5 EKG16895.1 - 5.3e-66 222.7 2.8 7.7e-66 222.2 1.9 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EKG16895.1 - 9.2e-31 106.7 0.1 1.5e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 EKG16896.1 - 6.6e-38 129.6 0.0 8.6e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EKG16896.1 - 7.3e-09 35.6 2.0 1.6e-08 34.5 1.4 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EKG16896.1 - 0.00044 20.1 0.0 0.00069 19.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Menin PF05053.8 EKG16896.1 - 1 7.4 3.5 1.4 7.0 2.4 1.1 1 0 0 1 1 1 0 Menin IF-2B PF01008.12 EKG16897.1 - 4.2e-75 252.3 0.0 5.4e-75 251.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PP_kinase_C PF13090.1 EKG16897.1 - 0.055 12.0 0.1 0.083 11.4 0.1 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain Sugar_tr PF00083.19 EKG16898.1 - 3.5e-27 95.0 0.0 3.7e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG16898.1 - 4.5e-06 25.6 0.0 4.5e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 EKG16899.1 - 5.3e-05 22.3 0.0 5.6e-05 22.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3176 PF11374.3 EKG16900.1 - 1.6e-26 92.3 0.1 6e-26 90.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) MFS_1 PF07690.11 EKG16901.1 - 4.1e-32 111.2 28.2 5.3e-32 110.9 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EKG16901.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1228 PF06779.9 EKG16901.1 - 0.35 10.9 5.4 0.21 11.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Pec_lyase_C PF00544.14 EKG16902.1 - 3.1e-16 59.4 6.6 8.5e-16 58.0 4.6 1.7 1 1 0 1 1 1 1 Pectate lyase CRAL_TRIO PF00650.15 EKG16903.1 - 1.4e-26 92.9 0.0 2e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EKG16903.1 - 2.9e-11 43.2 0.1 9.2e-11 41.7 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EKG16903.1 - 0.018 14.9 0.1 0.14 12.0 0.0 2.1 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain I-set PF07679.11 EKG16904.1 - 0.01 15.6 0.0 4.1 7.3 0.0 4.1 4 0 0 4 4 4 0 Immunoglobulin I-set domain Peptidase_M20 PF01546.23 EKG16904.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cupredoxin_1 PF13473.1 EKG16904.1 - 0.15 11.9 0.0 0.49 10.3 0.0 1.8 1 0 0 1 1 1 0 Cupredoxin-like domain Peptidase_C12 PF01088.16 EKG16905.1 - 1.1e-61 207.7 0.1 2.2e-61 206.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyco_hydro_42M PF08532.5 EKG16905.1 - 0.13 11.3 0.0 0.34 10.0 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain Rhomboid PF01694.17 EKG16906.1 - 4.1e-26 91.7 2.0 4.1e-26 91.7 1.4 1.5 2 0 0 2 2 2 1 Rhomboid family DEAD PF00270.24 EKG16907.1 - 1e-41 142.2 0.0 1.4e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG16907.1 - 2.4e-23 81.7 0.1 4.1e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EKG16907.1 - 0.1 11.6 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MFS_1 PF07690.11 EKG16909.1 - 1.6e-16 59.9 11.8 2.6e-16 59.2 8.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_23 PF13489.1 EKG16910.1 - 9.4e-19 67.6 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG16910.1 - 3.8e-11 43.3 0.0 1.7e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG16910.1 - 6.6e-11 42.5 0.0 1.5e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG16910.1 - 2e-10 40.4 0.0 4.8e-09 35.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG16910.1 - 9.7e-10 39.0 0.0 5.6e-09 36.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG16910.1 - 7.1e-05 22.0 0.0 0.0003 19.9 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EKG16910.1 - 0.001 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG16910.1 - 0.002 18.1 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EKG16910.1 - 0.0045 16.4 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 EKG16910.1 - 0.0072 15.5 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase CMAS PF02353.15 EKG16910.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EKG16910.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EKG16910.1 - 0.021 13.8 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EKG16910.1 - 0.037 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF2718 PF10918.3 EKG16910.1 - 0.18 11.9 0.2 0.49 10.4 0.1 1.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2718) KGG PF10685.4 EKG16911.1 - 1.7e-11 43.7 4.1 1.8e-09 37.3 0.1 3.9 4 0 0 4 4 4 3 Stress-induced bacterial acidophilic repeat motif Toxin_17 PF08086.6 EKG16911.1 - 0.0095 15.9 0.5 5.5 7.1 0.0 2.4 2 0 0 2 2 2 2 Ergtoxin family UDG PF03167.14 EKG16912.1 - 2.6e-25 88.6 0.1 3.8e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2673 PF10880.3 EKG16912.1 - 0.14 12.2 0.2 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Bromodomain PF00439.20 EKG16913.1 - 5.5e-37 125.5 12.6 1.8e-18 66.2 2.7 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EKG16913.1 - 3.2e-19 68.8 0.8 7.4e-19 67.6 0.6 1.7 1 0 0 1 1 1 1 BAH domain Nucleoplasmin PF03066.10 EKG16913.1 - 0.054 13.0 10.5 0.17 11.4 7.3 1.8 1 0 0 1 1 1 0 Nucleoplasmin RasGAP PF00616.14 EKG16913.1 - 0.35 10.5 6.6 0.38 10.3 0.4 2.4 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase CENP-B_dimeris PF09026.5 EKG16913.1 - 0.42 10.8 16.1 0.34 11.1 8.7 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop PF01798.13 EKG16914.1 - 1.3e-56 190.0 0.2 2.5e-56 189.1 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EKG16914.1 - 1.4e-24 85.5 0.1 3e-24 84.5 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EKG16914.1 - 1.1e-20 73.4 0.1 1.1e-20 73.4 0.0 2.9 3 0 0 3 3 3 1 NOP5NT (NUC127) domain Thi4 PF01946.12 EKG16915.1 - 1.3e-87 292.7 0.1 1.5e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Thi4 family Cpn60_TCP1 PF00118.19 EKG16918.1 - 4.4e-142 474.1 5.6 5.6e-142 473.7 3.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aa_trans PF01490.13 EKG16918.1 - 9.1e-38 129.7 28.8 1.3e-37 129.2 20.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bromodomain PF00439.20 EKG16919.1 - 8e-20 70.5 2.9 8.9e-20 70.4 0.2 2.4 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.8 EKG16919.1 - 8.9e-09 34.9 0.0 2.9e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated VanZ PF04892.7 EKG16920.1 - 5.6e-11 42.5 0.1 7.2e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 VanZ like family RseC_MucC PF04246.7 EKG16920.1 - 0.062 12.8 0.3 3.1 7.3 0.0 2.7 1 1 2 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.1 EKG16920.1 - 0.35 10.2 4.4 10 5.4 1.9 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) HEAT PF02985.17 EKG16921.1 - 1.5e-19 68.2 7.3 0.0033 17.3 0.0 10.9 11 0 0 11 11 10 4 HEAT repeat HEAT_EZ PF13513.1 EKG16921.1 - 1.6e-18 66.5 17.5 1.9e-07 31.3 0.1 9.6 9 2 2 11 11 9 3 HEAT-like repeat HEAT_2 PF13646.1 EKG16921.1 - 4.2e-15 55.7 13.6 2.4e-07 30.9 0.3 8.9 5 3 5 10 10 9 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EKG16921.1 - 5.3e-11 42.7 0.6 0.011 16.0 0.0 6.0 3 2 3 6 6 6 3 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EKG16921.1 - 9.3e-08 31.9 0.1 0.015 15.0 0.0 4.7 3 1 1 4 4 4 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EKG16921.1 - 1.5e-06 27.7 0.1 0.013 14.9 0.1 4.6 3 2 1 5 5 5 1 CLASP N terminal MMS19_C PF12460.3 EKG16921.1 - 7.3e-06 24.9 3.4 2.6e-05 23.1 0.6 2.9 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal Proteasom_PSMB PF10508.4 EKG16921.1 - 8e-05 21.0 0.9 0.0011 17.3 0.0 2.8 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit TFCD_C PF12612.3 EKG16921.1 - 0.0016 17.9 2.9 0.49 9.7 0.0 4.8 5 0 0 5 5 5 1 Tubulin folding cofactor D C terminal FAA_hydrolase_N PF09298.6 EKG16921.1 - 0.0029 17.5 0.3 1.7 8.7 0.1 3.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal IBN_N PF03810.14 EKG16921.1 - 0.003 17.4 0.0 0.15 11.9 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.9 EKG16921.1 - 0.0044 16.1 3.6 0.17 10.9 0.1 3.8 3 1 0 3 3 3 1 V-ATPase subunit H DUF3385 PF11865.3 EKG16921.1 - 0.014 15.3 5.6 11 5.9 0.0 5.0 4 1 1 6 6 6 0 Domain of unknown function (DUF3385) DUF3535 PF12054.3 EKG16921.1 - 0.099 11.2 3.1 0.13 10.9 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3535) Arm PF00514.18 EKG16921.1 - 0.37 10.7 5.1 9.2 6.2 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CBS PF00571.23 EKG16922.1 - 1.7e-41 139.7 4.7 1.8e-10 40.3 0.0 4.4 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 EKG16922.1 - 1.3e-07 31.1 0.0 3.6e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 PB1 domain Ribosomal_S26e PF01283.14 EKG16923.1 - 2.5e-49 166.2 7.9 2.5e-49 166.2 5.5 2.1 3 0 0 3 3 3 1 Ribosomal protein S26e ELYS PF13934.1 EKG16924.1 - 1.1e-56 192.1 2.4 1.4e-56 191.7 1.7 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly Ribonuclease_T2 PF00445.13 EKG16926.1 - 2e-45 154.7 0.6 2e-45 154.7 0.4 1.6 2 0 0 2 2 2 1 Ribonuclease T2 family IBR PF01485.16 EKG16927.1 - 2.6e-05 23.9 5.5 2.6e-05 23.9 3.8 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EKG16927.1 - 0.028 14.0 3.4 0.028 14.0 2.4 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EKG16928.1 - 2e-11 43.6 49.0 7.5e-07 28.9 10.4 4.8 4 1 0 4 4 4 3 IBR domain Zn_Tnp_IS91 PF14319.1 EKG16928.1 - 0.019 14.4 1.8 0.019 14.4 1.2 4.4 3 1 1 4 4 4 0 Transposase zinc-binding domain Latarcin PF10279.4 EKG16928.1 - 0.071 13.3 0.0 0.24 11.6 0.0 1.8 1 1 0 1 1 1 0 Latarcin precursor GST_N_3 PF13417.1 EKG16930.1 - 1e-26 92.9 0.1 2.4e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG16930.1 - 8.7e-17 60.8 0.1 2.5e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG16930.1 - 0.002 17.9 0.0 0.0047 16.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG16930.1 - 0.0037 17.7 0.1 0.019 15.4 0.0 2.1 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EKG16930.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin TTSSLRR PF12468.3 EKG16930.1 - 0.39 10.2 2.8 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein p450 PF00067.17 EKG16931.1 - 0.00019 20.0 0.0 0.00022 19.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0203 PF05254.7 EKG16933.1 - 5.1e-30 103.1 1.5 8.8e-30 102.3 1.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EKG16933.1 - 0.0031 17.5 0.6 0.009 16.0 0.4 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EKG16933.1 - 0.016 14.9 3.1 1.1 9.0 0.1 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EKG16933.1 - 0.067 13.1 0.2 0.28 11.1 0.1 2.2 2 0 0 2 2 2 0 CHCH domain DNA_pol_A_exo1 PF01612.15 EKG16934.1 - 5.9e-40 136.6 0.1 1.2e-39 135.5 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EKG16934.1 - 3.5e-25 88.1 0.0 9e-25 86.8 0.0 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EKG16934.1 - 1.9e-11 43.5 0.0 5e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 HRDC domain FLO_LFY PF01698.11 EKG16934.1 - 0.26 10.0 9.3 0.45 9.3 6.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein HGTP_anticodon2 PF12745.2 EKG16934.1 - 0.51 9.4 5.9 0.92 8.5 4.1 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MFS_1 PF07690.11 EKG16935.1 - 6.8e-07 28.3 6.0 6.8e-07 28.3 4.2 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Vps51 PF08700.6 EKG16936.1 - 0.0077 16.0 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 DUF1266 PF06889.6 EKG16936.1 - 0.025 14.3 0.4 0.035 13.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Mito_carr PF00153.22 EKG16937.1 - 7e-65 214.7 1.2 3.5e-21 74.7 0.1 4.2 4 0 0 4 4 4 4 Mitochondrial carrier protein F-box-like PF12937.2 EKG16938.1 - 7.1e-09 35.2 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG16938.1 - 0.00021 20.8 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain Radial_spoke_3 PF06098.6 EKG16939.1 - 0.73 8.7 6.0 0.88 8.5 4.2 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 NmrA PF05368.8 EKG16941.1 - 2e-13 50.1 0.0 1.6e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG16941.1 - 0.0001 22.3 0.1 0.00015 21.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding PEP_mutase PF13714.1 EKG16942.1 - 7.5e-45 153.0 0.0 9.1e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EKG16942.1 - 9e-22 76.9 0.1 1.3e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family TniQ PF06527.6 EKG16942.1 - 0.043 14.0 0.1 0.087 13.0 0.1 1.5 1 0 0 1 1 1 0 TniQ DUF221 PF02714.10 EKG16943.1 - 2.6e-60 203.9 5.1 3.7e-60 203.4 3.5 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EKG16943.1 - 3.8e-25 88.2 1.4 3.8e-25 88.2 1.0 1.9 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EKG16943.1 - 0.0096 16.4 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3341 PF11821.3 EKG16943.1 - 0.087 12.2 1.1 0.12 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) DUF937 PF06078.6 EKG16943.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) RRM_1 PF00076.17 EKG16943.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dynamin_N PF00350.18 EKG16944.1 - 5.4e-27 94.6 0.1 9.4e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EKG16944.1 - 2.7e-21 75.6 0.0 4.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 EKG16944.1 - 5.4e-06 26.2 0.4 2.2e-05 24.2 0.3 2.1 1 1 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EKG16944.1 - 0.008 16.1 0.0 0.041 13.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EKG16944.1 - 0.063 12.3 0.0 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AIG1 family PsaD PF02531.11 EKG16946.1 - 0.079 12.1 0.1 0.089 11.9 0.0 1.0 1 0 0 1 1 1 0 PsaD MFS_1 PF07690.11 EKG16948.1 - 1.4e-44 152.2 44.2 8.2e-44 149.7 29.0 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4243 PF14027.1 EKG16949.1 - 3.7e-74 250.1 2.9 4.9e-74 249.7 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) ADH_zinc_N PF00107.21 EKG16950.1 - 3.2e-11 42.9 0.1 6.1e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG16950.1 - 1.6e-09 37.4 0.0 3.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EKG16950.1 - 0.022 15.6 0.0 0.11 13.3 0.0 2.2 2 1 0 2 2 2 0 Zinc-binding dehydrogenase adh_short PF00106.20 EKG16950.1 - 0.12 12.3 0.8 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 short chain dehydrogenase p450 PF00067.17 EKG16951.1 - 9.7e-48 162.8 0.0 8.8e-47 159.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Oxidored_FMN PF00724.15 EKG16952.1 - 1.5e-45 155.6 0.0 2e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DAO PF01266.19 EKG16953.1 - 0.014 14.3 0.1 0.019 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EKG16953.1 - 0.045 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain CR6_interact PF10147.4 EKG16955.1 - 0.028 13.7 11.2 0.054 12.8 7.7 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF1675 PF07897.6 EKG16955.1 - 0.82 9.4 13.0 3.3 7.5 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1675) NMT PF01233.14 EKG16956.1 - 3e-79 264.3 0.1 4.9e-79 263.5 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EKG16956.1 - 8.3e-47 159.0 0.2 1.6e-46 158.1 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EKG16956.1 - 4.8e-05 23.2 0.1 0.0096 15.7 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG16956.1 - 0.0046 17.1 0.1 0.031 14.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG16956.1 - 0.034 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GTP_EFTU PF00009.22 EKG16957.1 - 1.5e-41 141.9 0.2 7.3e-41 139.6 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EKG16957.1 - 1.1e-33 114.9 0.0 2.4e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EKG16957.1 - 1.5e-30 105.2 0.1 3.1e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EKG16957.1 - 2.4e-25 88.1 0.1 4.4e-23 80.9 0.0 3.2 3 0 0 3 3 3 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EKG16957.1 - 4.3e-15 55.5 0.1 1e-14 54.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EKG16957.1 - 0.021 14.6 0.0 0.63 9.9 0.0 2.8 3 0 0 3 3 3 0 Putative phosphatase (DUF442) Abhydrolase_5 PF12695.2 EKG16958.1 - 2.1e-10 40.5 0.0 5.5e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG16958.1 - 5e-10 39.6 1.8 8e-10 38.9 1.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG16958.1 - 0.0002 21.0 0.1 0.00041 19.9 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase PF00151.14 EKG16958.1 - 0.00059 19.1 0.0 0.00076 18.7 0.0 1.1 1 0 0 1 1 1 1 Lipase Abhydrolase_2 PF02230.11 EKG16958.1 - 0.0091 15.4 0.4 1.1 8.6 0.1 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EKG16958.1 - 0.016 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EKG16958.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase EphA2_TM PF14575.1 EKG16959.1 - 0.059 13.7 2.3 0.14 12.5 1.6 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gon7 PF08738.5 EKG16959.1 - 0.12 12.3 0.1 0.12 12.3 0.0 2.7 2 0 0 2 2 2 0 Gon7 family MFS_1 PF07690.11 EKG16960.1 - 8.3e-29 100.3 25.5 8.3e-29 100.3 17.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily GST_N_2 PF13409.1 EKG16962.1 - 6.5e-09 35.6 0.2 1.5e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EKG16962.1 - 0.0026 17.9 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PAP2_3 PF14378.1 EKG16963.1 - 2.6e-20 72.7 17.8 1.5e-10 40.9 0.1 4.1 4 1 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.16 EKG16963.1 - 1.1 8.9 11.9 0.019 14.6 1.2 2.6 1 1 1 2 2 2 0 PAP2 superfamily Glyco_hydro_16 PF00722.16 EKG16964.1 - 3.2e-17 62.4 0.0 4.5e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RasGEF PF00617.14 EKG16965.1 - 3.1e-63 212.8 0.4 7.3e-63 211.6 0.3 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKG16965.1 - 2.7e-27 94.8 0.1 8.5e-27 93.2 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 EKG16965.1 - 6.7e-16 57.4 0.1 1.3e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG16965.1 - 1.8e-14 53.0 0.2 1.8e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EKG16965.1 - 8.4e-13 47.6 0.1 1.7e-12 46.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EKG16965.1 - 7.2e-05 22.5 0.0 0.00021 21.0 0.0 1.8 1 0 0 1 1 1 1 WW domain Ser_hydrolase PF06821.8 EKG16965.1 - 0.14 11.7 0.2 0.26 10.8 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase Fungal_trans PF04082.13 EKG16966.1 - 4.8e-17 61.7 3.3 7.3e-17 61.1 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EKG16966.1 - 2e-07 30.9 13.7 0.00011 22.3 4.0 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG16966.1 - 5.7e-05 23.1 13.3 0.0042 17.3 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG16966.1 - 0.0002 21.5 14.4 0.036 14.4 4.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EKG16966.1 - 0.71 9.8 4.2 16 5.5 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Chs3p PF12271.3 EKG16967.1 - 1.7e-138 460.5 17.1 1.9e-138 460.3 11.8 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Glyco_transf_34 PF05637.7 EKG16968.1 - 1.1e-17 64.3 0.2 1.6e-16 60.5 0.1 2.0 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_28 PF00295.12 EKG16971.1 - 1.4e-35 122.8 5.3 2e-35 122.3 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 EKG16971.1 - 0.0075 14.8 3.0 0.11 11.0 0.2 2.5 3 0 0 3 3 3 2 Pectinesterase WSC PF01822.14 EKG16974.1 - 5.3e-30 103.1 32.3 1.6e-17 63.1 5.8 2.9 3 0 0 3 3 3 2 WSC domain Glyoxal_oxid_N PF07250.6 EKG16974.1 - 8.4e-28 97.0 0.1 3.5e-25 88.5 0.0 3.4 3 1 1 4 4 4 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EKG16974.1 - 6.9e-26 90.2 0.1 1.5e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_4 PF14295.1 EKG16974.1 - 1.6e-06 27.7 0.7 1.6e-06 27.7 0.5 3.5 4 0 0 4 4 4 1 PAN domain Kelch_2 PF07646.10 EKG16974.1 - 0.08 12.7 2.6 1.6 8.6 0.1 4.1 5 0 0 5 5 5 0 Kelch motif Peptidase_M35 PF02102.10 EKG16975.1 - 7.3e-14 51.1 1.1 9.1e-14 50.8 0.8 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family DUF3445 PF11927.3 EKG16977.1 - 4.6e-64 216.1 0.0 1.4e-63 214.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) DUF2939 PF11159.3 EKG16977.1 - 0.089 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Fungal_trans_2 PF11951.3 EKG16978.1 - 2.7e-16 59.1 0.1 9.6e-15 54.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Dak1 PF02733.12 EKG16979.1 - 8.5e-113 376.2 0.0 1.2e-112 375.7 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EKG16979.1 - 2.2e-36 125.1 2.3 3.3e-36 124.5 1.6 1.3 1 0 0 1 1 1 1 DAK2 domain MFS_1 PF07690.11 EKG16980.1 - 1.4e-32 112.7 16.4 1.8e-32 112.4 11.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3302 PF11742.3 EKG16980.1 - 0.46 10.3 12.1 0.14 12.0 0.2 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF3302) adh_short_C2 PF13561.1 EKG16981.1 - 4.4e-18 65.9 0.0 5.2e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG16981.1 - 2.8e-07 30.5 0.1 3.4e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Utp8 PF10395.4 EKG16982.1 - 0.00029 19.2 0.4 0.0044 15.3 0.0 2.4 3 0 0 3 3 3 2 Utp8 family AAA PF00004.24 EKG16983.1 - 1.5e-08 34.8 0.7 1.5e-07 31.6 0.5 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EKG16983.1 - 1.2e-07 30.8 0.3 0.00036 19.3 0.0 2.8 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EKG16983.1 - 4.4e-06 26.8 0.1 1.1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG16983.1 - 0.00018 21.6 0.1 0.0017 18.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG16983.1 - 0.00027 21.7 0.0 0.0012 19.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 EKG16983.1 - 0.0013 18.4 0.0 0.0039 16.9 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 EKG16983.1 - 0.0059 16.9 0.2 0.046 14.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG16983.1 - 0.018 14.7 0.0 0.073 12.8 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EKG16983.1 - 0.033 14.0 0.0 0.1 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EKG16983.1 - 0.035 12.8 0.0 0.061 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EKG16983.1 - 0.064 13.1 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EKG16983.1 - 0.15 11.7 0.3 7.2 6.2 0.0 2.3 1 1 1 2 2 2 0 NTPase Histidinol_dh PF00815.15 EKG16984.1 - 5.6e-116 387.5 0.2 6.8e-116 387.2 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF3322 PF11795.3 EKG16984.1 - 0.044 13.4 0.1 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Fungal_trans PF04082.13 EKG16985.1 - 9.2e-15 54.2 0.1 1.9e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain cIII PF08134.6 EKG16985.1 - 0.012 15.1 0.5 0.033 13.7 0.3 1.7 1 0 0 1 1 1 0 cIII protein family SBP_bac_6 PF13343.1 EKG16986.1 - 1.3e-12 47.6 1.1 1.5e-12 47.3 0.8 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Zn_clus PF00172.13 EKG16987.1 - 1.3e-06 28.2 10.1 2.7e-06 27.1 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EKG16988.1 - 2.3e-27 95.7 0.0 4.4e-27 94.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG16988.1 - 5.2e-07 29.8 0.3 8e-07 29.2 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF2784 PF10861.3 EKG16988.1 - 0.055 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) TrkA_N PF02254.13 EKG16988.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EKG16988.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EKG16989.1 - 5.4e-21 74.9 0.2 7e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG16989.1 - 6.1e-13 49.1 0.1 8.7e-13 48.6 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG16989.1 - 6.2e-08 32.3 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EKG16989.1 - 2.8e-06 26.5 0.0 4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 EKG16989.1 - 0.00037 19.6 0.0 0.0023 17.1 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EKG16989.1 - 0.0004 20.6 0.0 0.00075 19.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EKG16989.1 - 0.00059 19.7 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 EKG16989.1 - 0.00095 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EKG16989.1 - 0.0012 19.2 0.1 0.0023 18.3 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EKG16989.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EKG16989.1 - 0.048 12.5 0.0 0.071 12.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 EKG16989.1 - 0.058 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EKG16989.1 - 0.072 11.7 0.0 0.18 10.4 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrbH PF07283.6 EKG16989.1 - 0.087 12.6 0.0 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 Conjugal transfer protein TrbH TrkA_N PF02254.13 EKG16989.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EKG16989.1 - 0.12 12.0 0.3 0.5 10.0 0.2 2.1 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PAS_6 PF08348.6 EKG16990.1 - 0.068 12.7 0.7 0.1 12.1 0.5 1.3 1 0 0 1 1 1 0 YheO-like PAS domain Fungal_trans PF04082.13 EKG16993.1 - 6e-23 81.0 0.0 9e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG16993.1 - 2e-07 30.7 10.6 2e-07 30.7 7.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EKG16994.1 - 2.9e-09 36.0 4.1 2.9e-09 36.0 2.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG16994.1 - 0.00031 19.4 5.1 0.00049 18.7 3.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter NfeD PF01957.13 EKG16994.1 - 0.14 12.2 1.1 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Spo7 PF03907.8 EKG16995.1 - 0.064 12.8 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Spo7-like protein DHDPS PF00701.17 EKG16996.1 - 8.3e-25 86.9 0.0 1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF4598 PF15370.1 EKG16997.1 - 1.7e-26 92.6 4.7 1.7e-26 92.6 3.3 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) IF4E PF01652.13 EKG16998.1 - 5e-38 130.2 0.6 7e-38 129.7 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tnp_P_element PF12017.3 EKG16998.1 - 0.15 11.3 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Transposase protein GDA1_CD39 PF01150.12 EKG16999.1 - 7.1e-96 321.3 0.0 9.4e-96 320.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C97 PF05903.9 EKG17000.1 - 1.1e-26 93.4 0.1 1.2e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EKG17002.1 - 2.9e-34 118.0 1.1 3e-34 118.0 0.8 1.0 1 0 0 1 1 1 1 PUL domain HEAT_2 PF13646.1 EKG17002.1 - 0.28 11.4 5.1 5.4 7.3 2.9 2.4 1 1 1 2 2 2 0 HEAT repeats PGP_phosphatase PF09419.5 EKG17003.1 - 2.6e-67 225.3 0.0 3e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EKG17003.1 - 0.00044 19.8 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EKG17003.1 - 0.0061 16.8 0.0 0.01 16.0 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase LSM PF01423.17 EKG17004.1 - 9.8e-15 53.8 0.3 1.3e-14 53.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKG17004.1 - 0.024 14.5 0.2 0.042 13.7 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 EKG17004.1 - 0.047 13.4 0.1 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein Adaptin_binding PF10199.4 EKG17005.1 - 1.6e-17 64.1 7.0 8.8e-17 61.6 4.9 1.9 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF591 PF04569.9 EKG17006.1 - 0.035 14.1 0.9 0.035 14.1 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function CR6_interact PF10147.4 EKG17006.1 - 0.041 13.2 1.7 0.075 12.3 1.1 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Ribosomal_L32e PF01655.13 EKG17007.1 - 7.7e-51 170.7 2.9 1.2e-50 170.1 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 Gp_UL130 PF11668.3 EKG17007.1 - 0.031 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Cullin PF00888.17 EKG17008.1 - 3.4e-128 428.7 0.4 4.2e-128 428.4 0.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EKG17008.1 - 4.7e-25 87.1 1.5 1.1e-24 86.0 1.0 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Dynamin_N PF00350.18 EKG17009.1 - 8.3e-45 152.6 0.0 1.4e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EKG17009.1 - 4.4e-09 35.5 0.0 8.7e-09 34.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EKG17009.1 - 0.0017 18.3 0.0 0.0063 16.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKG17009.1 - 0.0039 17.6 0.0 0.0097 16.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EKG17009.1 - 0.05 13.5 0.1 0.3 11.0 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 EKG17009.1 - 0.15 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain GATase_4 PF13230.1 EKG17010.1 - 1.4e-15 56.7 0.3 1e-13 50.6 0.2 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EKG17010.1 - 1.5e-10 41.1 0.0 3.5e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EKG17010.1 - 3.6e-07 29.2 0.0 6.5e-06 25.0 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferases class-II FAD_binding_4 PF01565.18 EKG17011.1 - 1e-26 93.0 2.8 1e-26 93.0 1.9 2.3 3 1 1 4 4 4 1 FAD binding domain Chitin_bind_1 PF00187.14 EKG17011.1 - 0.00011 22.0 27.2 0.00011 22.0 17.8 1.9 1 1 0 1 1 1 1 Chitin recognition protein Phe_ZIP PF08916.6 EKG17012.1 - 0.11 12.8 0.2 0.28 11.5 0.0 1.8 2 0 0 2 2 2 0 Phenylalanine zipper zf-C2H2 PF00096.21 EKG17013.1 - 6.4e-07 29.3 15.5 2.6e-05 24.2 1.9 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG17013.1 - 1.7e-05 24.8 3.3 1.7e-05 24.8 2.3 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EKG17013.1 - 0.0012 18.9 0.7 0.003 17.6 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EKG17013.1 - 0.0014 18.8 0.7 0.0014 18.8 0.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-TRAF PF02176.13 EKG17013.1 - 1.4 9.3 6.2 0.43 11.0 1.7 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 EKG17013.1 - 4 7.6 7.2 8.6 6.5 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SLT PF01464.15 EKG17014.1 - 0.0021 17.5 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Pectate_lyase_3 PF12708.2 EKG17015.1 - 7.9e-29 101.3 2.3 5.9e-13 49.4 0.7 3.9 3 2 1 4 4 4 3 Pectate lyase superfamily protein End_N_terminal PF12218.3 EKG17015.1 - 0.025 14.0 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Mito_carr PF00153.22 EKG17016.1 - 2.2e-66 219.6 5.4 1.7e-23 82.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dynamin_N PF00350.18 EKG17017.1 - 1.7e-16 60.4 1.4 1e-15 57.9 0.0 2.9 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EKG17017.1 - 1.8e-06 27.9 0.0 1.8e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EKG17017.1 - 0.00026 21.2 0.5 0.0021 18.3 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 EKG17017.1 - 0.004 17.9 0.2 0.13 13.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKG17017.1 - 0.0071 15.5 0.0 0.042 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EKG17017.1 - 0.01 16.3 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 EKG17017.1 - 0.012 14.7 0.7 0.08 12.0 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin IIGP PF05049.8 EKG17017.1 - 0.016 14.0 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EKG17017.1 - 0.027 14.4 0.4 0.31 11.0 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain AIG1 PF04548.11 EKG17017.1 - 0.042 12.9 0.0 0.12 11.4 0.0 1.8 1 0 0 1 1 1 0 AIG1 family PRK PF00485.13 EKG17017.1 - 0.058 12.9 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EKG17017.1 - 0.14 12.3 0.7 0.93 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Med9 PF07544.8 EKG17017.1 - 0.37 10.5 5.7 0.52 10.0 0.1 3.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1664 PF07889.7 EKG17017.1 - 0.48 10.2 8.6 1.3 8.8 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) AAA_23 PF13476.1 EKG17017.1 - 6.8 6.9 18.6 1.9 8.7 0.2 3.4 3 0 0 3 3 3 0 AAA domain TPR_MLP1_2 PF07926.7 EKG17017.1 - 9.1 6.0 19.2 2.4 7.8 3.9 4.0 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF3074 PF11274.3 EKG17019.1 - 4.7e-55 186.0 3.5 1.6e-54 184.3 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3074) Allexi_40kDa PF05549.6 EKG17019.1 - 1 8.6 5.7 1.7 7.8 3.9 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein TPR_MLP1_2 PF07926.7 EKG17019.1 - 3.8 7.2 27.8 19 4.9 19.2 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PaaA_PaaC PF05138.7 EKG17020.1 - 0.077 11.9 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DUF1786 PF08735.5 EKG17020.1 - 0.085 12.0 0.3 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Vac_ImportDeg PF09783.4 EKG17021.1 - 4.2e-38 130.6 1.1 7.8e-23 80.8 0.1 3.7 3 1 0 3 3 3 2 Vacuolar import and degradation protein Med10 PF09748.4 EKG17022.1 - 1.9e-39 134.3 0.7 2.3e-39 134.1 0.5 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EKG17022.1 - 0.00094 18.7 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) Flagellin_N PF00669.15 EKG17022.1 - 0.088 12.5 0.2 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region Syntaxin PF00804.20 EKG17022.1 - 0.1 12.7 0.1 1.7 8.8 0.0 2.1 2 0 0 2 2 2 0 Syntaxin PXA PF02194.10 EKG17023.1 - 8.4e-21 74.3 0.7 1.4e-20 73.6 0.2 1.5 2 0 0 2 2 2 1 PXA domain HTH_Tnp_Tc5 PF03221.11 EKG17024.1 - 2.3e-15 56.1 0.2 4.6e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EKG17024.1 - 1.3e-06 27.7 0.1 2.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EKG17024.1 - 0.0026 17.4 0.0 0.0077 15.9 0.0 1.8 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.11 EKG17024.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 EKG17024.1 - 0.034 13.7 0.0 0.078 12.5 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.2 EKG17024.1 - 0.039 13.6 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 EKG17024.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.1 EKG17024.1 - 0.089 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease TGS PF02824.16 EKG17025.1 - 5.9e-23 80.4 0.0 1.5e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EKG17025.1 - 1.3e-18 67.0 0.1 3.7e-18 65.5 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG17025.1 - 9.5e-10 37.9 0.1 5.6e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EKG17025.1 - 6.8e-05 22.3 0.2 1.1 8.5 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EKG17025.1 - 0.0001 22.1 0.1 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EKG17025.1 - 0.0055 17.2 0.0 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EKG17025.1 - 0.0065 15.2 0.1 0.016 13.9 0.1 1.7 1 0 0 1 1 1 1 ArgK protein AAA_28 PF13521.1 EKG17025.1 - 0.12 12.3 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF211 PF02680.9 EKG17025.1 - 0.18 11.6 1.5 0.3 10.9 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 CDO_I PF05995.7 EKG17026.1 - 3.3e-41 140.3 0.0 3.7e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EKG17026.1 - 1.2e-05 24.7 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Glyco_transf_90 PF05686.7 EKG17027.1 - 2.1e-17 62.9 3.6 1.5e-13 50.2 2.5 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Pyridoxal_deC PF00282.14 EKG17028.1 - 8e-78 261.4 0.0 3.2e-77 259.4 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EKG17028.1 - 3.9e-05 22.9 0.0 5.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EKG17028.1 - 0.0018 17.0 0.0 0.0031 16.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.14 EKG17029.1 - 1.3e-14 52.7 0.0 0.32 10.5 0.0 7.8 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat RINT1_TIP1 PF04437.8 EKG17030.1 - 3e-149 497.7 0.0 4.5e-149 497.1 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Filament PF00038.16 EKG17030.1 - 0.008 15.6 8.9 0.014 14.8 6.2 1.4 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 EKG17030.1 - 0.013 15.2 5.3 0.026 14.2 3.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 EKG17030.1 - 0.17 11.5 5.8 4.3 6.9 4.0 2.8 3 0 0 3 3 3 0 Mnd1 family Nsp1_C PF05064.8 EKG17030.1 - 0.37 10.4 9.2 4.1 7.0 0.3 2.9 2 1 1 3 3 3 0 Nsp1-like C-terminal region APG6 PF04111.7 EKG17030.1 - 0.72 8.8 8.6 1.3 8.0 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ATP-synt_B PF00430.13 EKG17030.1 - 1.7 8.4 7.6 0.58 9.9 3.0 1.9 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DUF904 PF06005.7 EKG17030.1 - 4.1 7.7 9.5 20 5.5 4.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Folliculin PF11704.3 EKG17031.1 - 3.5e-34 117.8 0.0 9.1e-34 116.4 0.0 1.7 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport FAD_binding_4 PF01565.18 EKG17033.1 - 1.1e-08 34.7 0.1 2.9e-06 26.7 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain zf-H2C2 PF09337.5 EKG17035.1 - 3.7e-18 64.6 7.0 5.6e-18 64.0 4.4 1.7 1 1 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EKG17035.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Imm47 PF15586.1 EKG17035.1 - 0.019 14.8 0.2 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 47 Acetyltransf_4 PF13420.1 EKG17035.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG17035.1 - 0.07 13.2 0.1 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain K_channel_TID PF07941.6 EKG17035.1 - 0.89 9.8 8.1 0.76 10.0 1.1 2.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain AMMECR1 PF01871.12 EKG17036.1 - 1.6e-46 157.5 0.0 6.7e-46 155.5 0.0 1.8 2 0 0 2 2 2 1 AMMECR1 DUF3836 PF12930.2 EKG17036.1 - 0.15 11.5 2.3 0.27 10.7 1.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF3836) DUF2890 PF11081.3 EKG17036.1 - 0.61 10.1 6.9 0.98 9.4 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DLIC PF05783.6 EKG17036.1 - 1.3 7.5 4.4 1.8 7.1 3.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF2618 PF10940.3 EKG17037.1 - 0.059 13.1 2.4 1.2 9.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) ABM PF03992.11 EKG17038.1 - 1.6e-07 31.2 0.1 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dabb PF07876.7 EKG17038.1 - 0.07 13.5 0.0 11 6.5 0.1 2.2 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain DUF1330 PF07045.6 EKG17038.1 - 0.1 12.4 0.1 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Ribonuclease PF00545.15 EKG17038.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 ribonuclease DUF2226 PF09987.4 EKG17039.1 - 0.088 11.9 0.1 0.095 11.8 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) DUF3328 PF11807.3 EKG17040.1 - 2.1e-30 106.0 0.2 2.5e-30 105.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) EGF_2 PF07974.8 EKG17041.1 - 0.012 15.7 5.2 0.018 15.1 3.6 1.3 1 0 0 1 1 1 0 EGF-like domain Defensin_2 PF01097.13 EKG17041.1 - 0.82 9.4 6.3 1.9 8.2 4.4 1.6 1 0 0 1 1 1 0 Arthropod defensin EGF PF00008.22 EKG17041.1 - 4.5 7.3 10.6 0.56 10.2 3.3 2.0 1 1 1 2 2 2 0 EGF-like domain p450 PF00067.17 EKG17042.1 - 4.6e-54 183.6 0.0 8e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EKG17043.1 - 6.9e-78 262.2 16.2 8.7e-78 261.8 11.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG17043.1 - 6.8e-32 110.5 24.2 2.4e-28 98.8 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.2 EKG17043.1 - 0.013 15.4 2.1 0.013 15.4 1.5 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3792) Methyltransf_11 PF08241.7 EKG17046.1 - 0.026 15.0 0.0 0.069 13.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SAP PF02037.22 EKG17047.1 - 1.6e-10 40.2 1.1 3.9e-10 38.9 0.1 2.1 2 0 0 2 2 2 1 SAP domain PDEase_I PF00233.14 EKG17049.1 - 2.6e-45 155.0 0.0 6.2e-42 143.9 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Dicty_CAR PF05462.6 EKG17052.1 - 2.9e-11 42.8 12.7 2.9e-11 42.8 8.8 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EKG17052.1 - 1.5e-08 34.4 14.2 1.5e-08 34.4 9.8 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 zf-LITAF-like PF10601.4 EKG17052.1 - 2.6 7.9 0.0 2.6 7.9 0.0 3.7 5 0 0 5 5 5 0 LITAF-like zinc ribbon domain Pneumo_att_G PF05539.6 EKG17052.1 - 4.1 6.6 11.0 5.2 6.3 5.7 2.0 2 0 0 2 2 2 0 Pneumovirinae attachment membrane glycoprotein G Pkinase PF00069.20 EKG17053.1 - 1.3e-77 260.4 0.0 1.6e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17053.1 - 2.1e-37 128.5 0.0 3.1e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG17053.1 - 0.0012 17.8 0.1 0.0059 15.5 0.0 2.0 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EKG17053.1 - 0.02 14.6 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EKG17053.1 - 0.072 12.1 0.1 0.16 11.0 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EKG17054.1 - 3.2e-36 121.9 3.4 2.6e-07 30.2 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EKG17054.1 - 5.5e-07 29.4 0.1 0.0095 15.6 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Peptidase_M18 PF02127.10 EKG17055.1 - 1.1e-165 551.4 0.0 1.3e-165 551.0 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EKG17055.1 - 0.0098 14.6 0.1 0.71 8.5 0.0 3.0 2 1 1 3 3 3 2 M42 glutamyl aminopeptidase DPM2 PF07297.7 EKG17056.1 - 1.3e-31 108.7 1.9 1.5e-31 108.5 1.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EKG17056.1 - 9.8e-05 21.9 1.3 0.0001 21.9 0.9 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.1 EKG17056.1 - 0.0029 17.1 3.3 0.071 12.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome oxidase c assembly DUF4083 PF13314.1 EKG17056.1 - 0.1 12.4 0.2 0.1 12.4 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF4229 PF14012.1 EKG17056.1 - 1.6 8.6 6.0 0.11 12.4 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) AA_permease_2 PF13520.1 EKG17057.1 - 1.7e-97 326.6 33.7 2.1e-97 326.3 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG17057.1 - 1.7e-22 79.4 29.2 2.2e-22 79.0 20.3 1.1 1 0 0 1 1 1 1 Amino acid permease Lipase_GDSL PF00657.17 EKG17058.1 - 2.8e-13 50.2 0.3 2.2e-12 47.2 0.2 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKG17058.1 - 9.1e-13 48.7 2.4 9.1e-13 48.7 1.7 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Esterase PF00756.15 EKG17059.1 - 3.2e-52 177.4 0.0 3.9e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EKG17059.1 - 2.9e-06 27.0 0.0 4.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG17059.1 - 1.5e-05 24.2 0.0 3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EKG17059.1 - 0.00073 19.4 0.0 0.0009 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EKG17059.1 - 0.0016 17.3 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase_phd PF10503.4 EKG17059.1 - 0.0017 17.6 0.0 0.027 13.7 0.0 2.0 2 0 0 2 2 2 1 Esterase PHB depolymerase Lipase_3 PF01764.20 EKG17059.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 EKG17059.1 - 0.032 13.7 0.0 0.4 10.1 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EKG17059.1 - 0.071 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.8 EKG17059.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein RNA_pol_Rpb6 PF01192.17 EKG17060.1 - 1.6e-23 82.1 0.2 2.6e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 EKG17061.1 - 7.5e-27 92.0 61.8 0.00011 22.3 1.3 10.6 11 0 0 11 11 11 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG17061.1 - 2e-19 68.3 63.4 0.00032 20.8 0.2 10.3 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG17061.1 - 6e-13 48.3 62.7 1.6e-07 31.2 0.9 10.9 11 0 0 11 11 11 5 Zinc-finger double domain zf-met PF12874.2 EKG17061.1 - 2.2e-07 30.8 22.6 2.7 8.3 0.1 9.2 10 0 0 10 10 10 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EKG17061.1 - 7.8e-05 22.6 33.0 0.078 13.1 0.4 9.4 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding FANCL_C PF11793.3 EKG17061.1 - 0.65 10.0 7.9 2.5 8.1 1.6 3.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C2HC_2 PF13913.1 EKG17061.1 - 5.9 6.6 15.9 1.6 8.4 0.0 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type SGL PF08450.7 EKG17062.1 - 0.02 14.2 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region MIF4G PF02854.14 EKG17063.1 - 6e-27 94.4 0.4 6e-27 94.4 0.3 1.8 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EKG17063.1 - 1.9e-23 82.3 0.0 9.6e-23 80.0 0.0 2.3 2 0 0 2 2 2 1 MA3 domain WD40 PF00400.27 EKG17064.1 - 3.3e-22 77.4 11.2 1.3e-07 31.1 0.3 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Asp PF00026.18 EKG17065.1 - 1e-39 136.6 0.0 1.4e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKG17065.1 - 0.00011 22.1 0.2 0.00038 20.4 0.2 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EKG17065.1 - 0.008 15.7 0.0 0.019 14.5 0.0 1.6 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal EB PF01683.13 EKG17066.1 - 0.12 12.4 1.5 0.28 11.2 1.1 1.6 1 0 0 1 1 1 0 EB module Foamy_virus_ENV PF03408.9 EKG17069.1 - 0.078 10.5 0.0 0.095 10.2 0.0 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein GLTT PF01744.15 EKG17070.1 - 0.037 13.4 0.1 0.037 13.4 0.1 7.3 9 0 0 9 9 9 0 GLTT repeat (6 copies) SecM PF06558.7 EKG17071.1 - 0.038 13.6 0.5 0.053 13.1 0.4 1.2 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) AMP-binding PF00501.23 EKG17074.1 - 5.6e-70 235.8 0.1 9.5e-70 235.0 0.1 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG17074.1 - 2.6e-12 47.5 0.0 6.9e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Grp1_Fun34_YaaH PF01184.14 EKG17075.1 - 1.5e-86 289.0 17.7 1.8e-86 288.7 12.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3951 PF13131.1 EKG17076.1 - 0.16 11.7 0.6 0.21 11.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) SNARE PF05739.14 EKG17077.1 - 3.4e-13 49.0 6.1 3.4e-13 49.0 4.2 2.9 3 1 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EKG17077.1 - 5.2e-07 29.7 0.0 5.2e-07 29.7 0.0 3.0 1 1 1 2 2 1 1 Syntaxin RPW8 PF05659.6 EKG17077.1 - 0.0082 15.6 2.5 0.096 12.2 0.2 2.7 3 0 0 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 IFT46_B_C PF12317.3 EKG17077.1 - 0.01 15.2 4.1 2.6 7.3 2.0 2.2 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal MerR-DNA-bind PF09278.6 EKG17077.1 - 0.041 14.2 4.7 2 8.8 0.0 2.8 2 0 0 2 2 2 0 MerR, DNA binding XH PF03469.9 EKG17077.1 - 0.045 13.4 10.0 0.17 11.5 1.6 2.5 2 1 1 3 3 3 0 XH domain Vac_Fusion PF02346.11 EKG17077.1 - 0.059 12.8 3.8 0.31 10.4 0.2 3.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein LXG PF04740.7 EKG17077.1 - 0.069 12.9 6.1 0.96 9.1 0.1 2.2 1 1 0 2 2 2 0 LXG domain of WXG superfamily MCPsignal PF00015.16 EKG17077.1 - 0.11 11.9 7.9 0.13 11.8 4.1 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Lipoprotein_6 PF01441.14 EKG17077.1 - 0.19 11.5 0.2 0.19 11.5 0.1 2.3 1 1 1 2 2 2 0 Lipoprotein Spectrin PF00435.16 EKG17077.1 - 0.25 11.6 8.1 10 6.4 0.9 3.5 2 1 2 4 4 4 0 Spectrin repeat Baculo_PEP_C PF04513.7 EKG17077.1 - 0.49 10.2 8.8 2.2 8.0 0.9 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EKG17077.1 - 0.54 10.5 7.8 4 7.7 0.1 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 EKG17077.1 - 0.99 9.3 5.0 0.66 9.8 1.0 2.3 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Mnd1 PF03962.10 EKG17077.1 - 1 8.9 9.7 5.7 6.5 5.8 2.4 2 1 0 2 2 2 0 Mnd1 family AAA_13 PF13166.1 EKG17077.1 - 1.7 7.0 10.0 2.2 6.6 6.0 1.5 1 1 0 1 1 1 0 AAA domain Gly-rich_Ago1 PF12764.2 EKG17077.1 - 3.1 8.4 6.0 0.84 10.2 0.1 2.5 2 1 0 2 2 2 0 Glycine-rich region of argonaut Fib_alpha PF08702.5 EKG17077.1 - 7.7 6.6 12.5 21 5.2 1.3 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NAPRTase PF04095.11 EKG17078.1 - 1.8e-50 171.5 0.2 3.6e-27 95.2 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family PH PF00169.24 EKG17082.1 - 5e-07 29.8 0.0 1.5e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EKG17082.1 - 0.00033 20.1 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF3677 PF12432.3 EKG17082.1 - 0.038 14.4 0.1 0.33 11.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3677) PH_11 PF15413.1 EKG17082.1 - 0.053 13.7 4.6 3.4 7.9 0.1 3.6 2 1 0 2 2 2 0 Pleckstrin homology domain Kri1_C PF12936.2 EKG17083.1 - 3.4e-30 103.8 0.5 3.4e-30 103.8 0.3 4.3 5 1 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EKG17083.1 - 3.8e-28 97.7 22.6 3.8e-28 97.7 15.6 5.3 5 2 0 5 5 5 1 KRI1-like family RabGAP-TBC PF00566.13 EKG17084.1 - 8.1e-39 133.3 0.3 1.2e-38 132.7 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF2917 PF11142.3 EKG17085.1 - 0.04 13.1 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) TPR_2 PF07719.12 EKG17088.1 - 7.7e-07 28.5 2.6 0.00036 20.2 0.9 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKG17088.1 - 3e-06 26.5 0.7 2e-05 23.9 0.5 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKG17088.1 - 1.2e-05 24.8 0.7 1.9e-05 24.1 0.5 1.3 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.1 EKG17088.1 - 5.9e-05 22.9 0.9 9e-05 22.3 0.6 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 EKG17088.1 - 0.00022 21.0 0.6 0.00034 20.4 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG17088.1 - 0.0027 18.3 0.7 0.005 17.4 0.5 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG17088.1 - 0.028 14.1 0.2 0.064 13.0 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG17088.1 - 0.046 14.2 0.2 24 5.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG17088.1 - 0.056 14.0 0.7 0.52 11.1 0.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EKG17088.1 - 0.086 12.6 0.2 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TORC_N PF12884.2 EKG17088.1 - 0.15 12.6 0.1 0.33 11.5 0.0 1.6 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus Stb3 PF10330.4 EKG17089.1 - 1.3e-31 108.0 0.0 2.4e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein Topoisom_bac PF01131.15 EKG17090.1 - 5.4e-87 292.2 0.0 1e-86 291.2 0.0 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.17 EKG17090.1 - 2.5e-19 69.0 0.0 5.3e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Toprim domain PDR_CDR PF06422.7 EKG17090.1 - 0.0037 16.9 0.1 0.03 13.9 0.1 2.2 2 0 0 2 2 2 1 CDR ABC transporter DUF1295 PF06966.7 EKG17091.1 - 1.2e-38 132.7 10.2 1.4e-38 132.4 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EKG17091.1 - 0.19 11.9 4.1 0.21 11.8 0.0 2.8 2 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NMT1 PF09084.6 EKG17092.1 - 1.8e-77 259.8 0.0 2.3e-77 259.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EKG17092.1 - 3.2e-08 33.2 0.3 0.081 12.2 0.0 3.8 2 1 2 4 4 4 3 NMT1-like family Glyco_hydro_16 PF00722.16 EKG17093.1 - 1.4e-37 128.7 8.6 3.1e-37 127.6 6.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fringe PF02434.11 EKG17094.1 - 0.00023 20.4 0.5 0.026 13.7 0.0 2.9 2 1 0 2 2 2 1 Fringe-like DUF416 PF04222.7 EKG17094.1 - 0.073 12.2 0.1 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF416) Peptidase_S8 PF00082.17 EKG17096.1 - 4.9e-44 150.5 1.7 6.9e-44 150.0 1.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EKG17096.1 - 1e-08 35.5 0.0 1.9e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DnaJ PF00226.26 EKG17099.1 - 1.6e-08 34.1 0.0 2.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EKG17099.1 - 7.9e-07 28.9 0.0 1.2e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EKG17099.1 - 1.7 8.0 9.7 0.043 13.1 1.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.15 EKG17100.1 - 8.7e-07 28.7 0.2 2e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4414 PF14377.1 EKG17100.1 - 0.042 13.7 4.7 0.068 13.0 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Syntaxin_2 PF14523.1 EKG17100.1 - 0.15 12.1 0.3 0.15 12.1 0.2 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DUF4611 PF15387.1 EKG17100.1 - 3.9 7.6 8.3 6.3 7.0 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) HEAT PF02985.17 EKG17101.1 - 6.3e-45 147.2 18.4 0.0058 16.6 0.1 13.4 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 EKG17101.1 - 9e-33 112.4 3.2 2.3e-08 34.1 0.0 7.6 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EKG17101.1 - 4.3e-12 46.1 9.6 0.0015 18.9 0.0 9.0 7 2 3 10 10 10 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EKG17101.1 - 2.2e-11 43.9 5.5 0.0004 20.7 0.1 7.8 4 4 4 9 9 9 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EKG17101.1 - 2.4e-07 29.5 3.7 7.3e-05 21.2 0.0 3.8 3 1 0 4 4 4 2 Adaptin N terminal region DUF2435 PF10363.4 EKG17101.1 - 0.00016 21.4 2.3 1.3 9.0 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2435) CLASP_N PF12348.3 EKG17101.1 - 0.00099 18.5 0.6 0.11 11.8 0.0 4.0 2 2 1 3 3 3 1 CLASP N terminal DNA_alkylation PF08713.6 EKG17101.1 - 0.0039 16.7 0.0 3.8 6.9 0.0 3.4 3 1 1 4 4 4 1 DNA alkylation repair enzyme Cnd1 PF12717.2 EKG17101.1 - 0.006 16.4 4.8 3 7.6 0.1 5.0 2 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EKG17101.1 - 0.066 13.0 3.5 32 4.5 0.0 5.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 EKG17101.1 - 0.11 10.6 2.0 0.66 8.1 0.0 2.7 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit B3_4 PF03483.12 EKG17102.1 - 1.9e-25 89.3 0.1 3.4e-25 88.5 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EKG17102.1 - 9.5e-17 60.5 0.0 9e-13 47.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain PHD PF00628.24 EKG17103.1 - 7.1e-11 41.6 9.2 7.1e-11 41.6 6.4 2.0 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 EKG17103.1 - 0.045 13.2 0.2 0.045 13.2 0.2 1.8 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DivIC PF04977.10 EKG17103.1 - 0.29 10.6 0.7 0.63 9.5 0.5 1.5 1 0 0 1 1 1 0 Septum formation initiator MAGE PF01454.14 EKG17104.1 - 1.3e-17 63.8 0.0 1.8e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 MAGE family Chalcone PF02431.10 EKG17105.1 - 3.6e-56 189.7 0.0 6.1e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Ribosomal_S3_C PF00189.15 EKG17107.1 - 2.5e-16 59.6 0.0 5.1e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EKG17107.1 - 6.2e-12 44.9 0.0 1.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 KH domain CoA_binding_2 PF13380.1 EKG17107.1 - 0.033 14.3 0.5 0.14 12.3 0.1 2.2 2 1 1 3 3 3 0 CoA binding domain UN_NPL4 PF11543.3 EKG17107.1 - 0.077 13.2 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 EKG17108.1 - 4.1e-110 367.8 0.0 5.5e-110 367.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EKG17108.1 - 0.003 17.8 0.1 0.0092 16.2 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EKG17108.1 - 0.076 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EKG17108.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Cellulase PF00150.13 EKG17109.1 - 2.1e-06 27.1 0.0 4.4e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Methyltransf_11 PF08241.7 EKG17111.1 - 1.6e-11 44.5 0.0 4e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG17111.1 - 4.9e-11 42.6 0.0 7.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG17111.1 - 2.8e-08 34.1 0.0 5.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG17111.1 - 1.9e-06 27.5 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG17111.1 - 7.2e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EKG17111.1 - 0.019 15.3 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dynactin_p62 PF05502.8 EKG17112.1 - 3.9e-154 514.0 0.0 5.9e-154 513.4 0.0 1.3 1 0 0 1 1 1 1 Dynactin p62 family Mu-like_Com PF10122.4 EKG17112.1 - 0.32 10.0 7.4 2.5 7.2 0.3 2.8 2 0 0 2 2 2 0 Mu-like prophage protein Com PVL_ORF50 PF07768.6 EKG17112.1 - 3.3 7.7 6.2 0.38 10.7 0.7 2.0 2 0 0 2 2 2 0 PVL ORF-50-like family WD40 PF00400.27 EKG17113.1 - 1.8e-44 148.0 10.4 1.2e-10 40.7 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EKG17113.1 - 7.9e-07 28.7 0.6 1.6e-06 27.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG17113.1 - 2e-05 24.1 0.3 4e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 EKG17113.1 - 6.4e-05 22.5 1.0 0.002 17.6 0.6 2.6 2 1 1 3 3 3 1 PQQ-like domain Nup160 PF11715.3 EKG17113.1 - 9.9e-05 20.6 0.0 0.00064 17.9 0.0 2.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 PQQ PF01011.16 EKG17113.1 - 0.0002 20.7 0.2 4.5 6.9 0.0 3.8 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.1 EKG17113.1 - 0.041 14.1 2.8 24 5.3 0.1 5.2 5 1 1 6 6 6 0 PQQ-like domain Pkinase PF00069.20 EKG17115.1 - 1.4e-15 57.1 0.0 1.3e-08 34.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain START PF01852.14 EKG17115.1 - 0.074 12.3 0.4 0.49 9.6 0.1 2.1 2 0 0 2 2 2 0 START domain Ribosomal_S7e PF01251.13 EKG17116.1 - 3.7e-83 277.6 0.3 4.1e-83 277.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e GST_C_3 PF14497.1 EKG17117.1 - 5.6e-10 39.5 0.0 8.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG17117.1 - 1.8e-06 27.8 0.2 3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG17117.1 - 0.0031 17.3 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF423 PF04241.10 EKG17119.1 - 1.4e-16 60.1 5.6 3.7e-10 39.5 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF423) Trep_Strep PF09605.5 EKG17119.1 - 1.7 8.2 4.4 0.46 10.1 0.7 1.7 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) LRR_6 PF13516.1 EKG17120.1 - 3.7e-12 44.9 16.4 1.1 9.4 0.0 11.5 11 1 1 12 12 12 3 Leucine Rich repeat LRR_4 PF12799.2 EKG17120.1 - 4e-12 45.4 9.6 0.41 10.3 0.1 7.7 2 1 5 8 8 8 6 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EKG17120.1 - 8.2e-11 41.4 0.7 1.7e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EKG17120.1 - 1e-06 28.3 22.6 0.21 11.3 0.1 6.2 3 2 4 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EKG17120.1 - 0.00026 20.5 28.1 12 6.3 0.0 10.7 10 2 1 11 11 11 1 Leucine Rich Repeat F-box PF00646.28 EKG17120.1 - 0.019 14.6 3.4 0.032 13.8 0.1 3.0 3 0 0 3 3 3 0 F-box domain DUF1699 PF08004.6 EKG17120.1 - 0.056 12.9 0.2 0.31 10.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Pkinase PF00069.20 EKG17121.1 - 3.2e-39 134.6 0.0 5e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17121.1 - 8.8e-31 106.9 0.0 1.2e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG17121.1 - 0.0022 17.0 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG17121.1 - 0.051 13.3 2.0 5.3 6.6 0.0 3.2 2 2 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EKG17121.1 - 0.061 12.3 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_18 PF12847.2 EKG17122.1 - 1.1e-17 64.6 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG17122.1 - 2.1e-17 63.1 0.0 3.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG17122.1 - 2.3e-08 34.0 0.0 3.6e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG17122.1 - 2.6e-08 34.2 0.0 4.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG17122.1 - 1.7e-06 27.8 0.0 5e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG17122.1 - 3.9e-05 24.0 0.0 0.00016 22.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG17122.1 - 5.2e-05 23.5 0.0 8.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EKG17122.1 - 0.00013 21.6 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EKG17122.1 - 0.00015 21.8 0.0 0.00039 20.5 0.0 1.7 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 EKG17122.1 - 0.0036 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EKG17122.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EKG17122.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.7 EKG17122.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW p450 PF00067.17 EKG17123.1 - 1.5e-54 185.2 0.0 1.5e-53 182.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Mucin PF01456.12 EKG17127.1 - 3.6 7.3 11.1 5.2 6.8 2.0 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_L7Ae PF01248.21 EKG17128.1 - 4.5e-28 96.5 1.2 5.7e-28 96.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EKG17128.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Fungal_trans PF04082.13 EKG17129.1 - 3.2e-09 36.0 1.0 5.3e-09 35.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Wzz PF02706.10 EKG17129.1 - 0.064 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Chain length determinant protein Equine_IAV_S2 PF06502.6 EKG17130.1 - 0.093 12.6 0.1 0.35 10.7 0.1 2.0 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein F-box-like PF12937.2 EKG17131.1 - 2.2e-13 49.6 1.3 5.1e-08 32.5 0.0 2.9 2 0 0 2 2 2 2 F-box-like F-box-like_2 PF13013.1 EKG17131.1 - 1.1e-06 28.2 4.3 0.035 13.8 0.2 3.7 3 0 0 3 3 3 3 F-box-like domain F-box PF00646.28 EKG17131.1 - 1.7e-05 24.3 12.9 0.00064 19.2 2.2 3.5 3 1 0 3 3 3 2 F-box domain F-box-like PF12937.2 EKG17134.1 - 0.00091 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG17134.1 - 0.027 14.1 0.0 0.092 12.4 0.0 1.9 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EKG17135.1 - 0.0025 17.4 0.1 0.0066 16.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 EKG17138.1 - 4.4e-35 121.0 18.4 4.4e-35 121.0 12.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Aconitase_C PF00694.14 EKG17139.1 - 7.5e-46 155.4 0.0 1.1e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Aconitase C-terminal domain HET PF06985.6 EKG17140.1 - 1.5e-18 67.2 0.1 4.4e-18 65.7 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.23 EKG17141.1 - 0.019 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Dynamin_N PF00350.18 EKG17141.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Dynamin family Hexapep PF00132.19 EKG17142.1 - 3.8e-14 51.4 6.8 2.4e-11 42.6 1.5 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EKG17142.1 - 1e-13 50.5 4.6 1.4e-11 43.7 1.0 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase adh_short PF00106.20 EKG17143.1 - 2.2e-13 50.4 0.0 3.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG17143.1 - 6.2e-13 49.0 0.1 1.2e-12 48.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG17143.1 - 0.00017 21.3 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Flg_bbr_C PF06429.8 EKG17143.1 - 0.045 13.6 0.2 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 Flagellar basal body rod FlgEFG protein C-terminal WD40 PF00400.27 EKG17144.1 - 2.8e-07 30.1 8.8 0.33 10.9 0.0 7.2 8 0 0 8 8 8 2 WD domain, G-beta repeat NACHT PF05729.7 EKG17144.1 - 2e-06 27.5 0.0 4.2e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EKG17144.1 - 1.4e-05 24.7 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.1 EKG17144.1 - 0.00043 20.3 0.1 0.0038 17.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 EKG17144.1 - 0.00046 19.5 0.1 0.0023 17.2 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EKG17144.1 - 0.0007 19.5 0.0 0.0018 18.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG17144.1 - 0.065 12.9 0.0 0.26 11.0 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family AAA_19 PF13245.1 EKG17144.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF1512 PF07431.7 EKG17144.1 - 0.38 9.4 0.0 0.64 8.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) MFS_1 PF07690.11 EKG17146.1 - 4.5e-42 144.0 33.1 3.1e-39 134.6 10.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG17146.1 - 1.3e-10 40.5 7.8 1.3e-10 40.5 5.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter CAP_N PF01213.14 EKG17146.1 - 0.45 9.7 6.9 0.7 9.1 4.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_4 PF01565.18 EKG17147.1 - 1.8e-22 79.2 0.3 2.7e-22 78.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Sec39 PF08314.6 EKG17149.1 - 1.7e-170 568.4 0.0 2e-170 568.2 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF2313 PF10076.4 EKG17149.1 - 0.059 12.7 0.1 0.36 10.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2313) YjbE PF11106.3 EKG17149.1 - 8.5 6.4 8.5 7.2 6.6 1.6 2.6 2 0 0 2 2 2 0 Exopolysaccharide production protein YjbE CoA_transf_3 PF02515.12 EKG17150.1 - 9e-29 100.0 0.0 1.5e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Tex_N PF09371.5 EKG17150.1 - 0.021 14.1 0.2 0.64 9.3 0.0 2.3 2 0 0 2 2 2 0 Tex-like protein N-terminal domain Fungal_trans PF04082.13 EKG17151.1 - 2e-27 95.6 0.1 4.6e-27 94.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain EBP PF05241.7 EKG17152.1 - 6.8e-07 28.4 4.8 3.1e-06 26.3 3.3 1.9 1 1 0 1 1 1 1 Emopamil binding protein MFS_1 PF07690.11 EKG17153.1 - 3.8e-26 91.6 43.8 4.7e-24 84.7 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG17153.1 - 9.4e-12 44.2 6.8 9.4e-12 44.2 4.7 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter zf-DHHC PF01529.15 EKG17154.1 - 1.8e-37 128.3 6.5 1.8e-37 128.3 4.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EKG17154.1 - 2.8e-31 107.7 0.1 9.5e-14 51.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG17154.1 - 7.1e-29 98.1 3.4 6.2e-07 28.9 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EKG17154.1 - 6.4e-22 77.5 3.7 2.6e-07 30.9 0.2 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG17154.1 - 1.1e-20 71.6 2.2 0.00022 21.1 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EKG17154.1 - 1.9e-18 66.0 8.9 1.9e-07 31.1 0.0 5.2 2 1 2 5 5 5 4 Ankyrin repeats (many copies) DZR PF12773.2 EKG17154.1 - 1.3 8.8 8.4 2.6 7.9 5.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon eIF3g PF12353.3 EKG17155.1 - 4.9e-46 155.7 9.9 7.4e-46 155.2 6.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EKG17155.1 - 7.3e-19 67.1 0.1 1.3e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG17155.1 - 5.7e-15 55.0 0.1 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG17155.1 - 3e-08 33.3 0.0 5.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKG17155.1 - 0.027 14.2 5.0 0.21 11.4 0.0 3.1 2 1 1 3 3 3 0 RNA binding motif VirionAssem_T7 PF11653.3 EKG17155.1 - 1.5 9.6 5.8 3.9 8.2 4.0 1.7 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein NmrA PF05368.8 EKG17156.1 - 1.1e-38 132.8 0.0 1.3e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG17156.1 - 2.6e-16 60.1 0.1 3.3e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG17156.1 - 1.8e-06 27.6 0.0 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG17156.1 - 2e-05 23.4 0.0 3.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG17156.1 - 4.1e-05 22.6 0.0 0.00011 21.2 0.0 1.7 2 1 0 2 2 2 1 Male sterility protein KR PF08659.5 EKG17156.1 - 0.00059 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKG17156.1 - 0.0026 17.6 0.0 0.0075 16.2 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase DapB_N PF01113.15 EKG17156.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EKG17156.1 - 0.021 13.7 0.0 0.61 8.9 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EKG17156.1 - 0.024 14.9 0.0 0.097 12.9 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG17156.1 - 0.057 13.8 0.1 0.17 12.3 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EKG17156.1 - 0.16 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Fer2_4 PF13510.1 EKG17156.1 - 0.17 11.6 0.1 14 5.5 0.0 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fungal_trans_2 PF11951.3 EKG17157.1 - 2.4e-21 75.7 1.5 1.5e-14 53.4 0.6 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17157.1 - 3e-07 30.2 11.5 5e-07 29.5 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 EKG17159.1 - 2.1e-07 30.6 10.1 3.5e-07 29.9 7.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EKG17159.1 - 4.2e-06 26.6 9.6 7.3e-06 25.8 6.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EKG17159.1 - 0.0011 19.2 8.5 0.0016 18.6 5.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor CDC27 PF09507.5 EKG17159.1 - 0.005 16.1 7.1 0.006 15.8 4.9 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SR-25 PF10500.4 EKG17159.1 - 0.0097 15.3 18.0 0.018 14.5 12.5 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EKG17159.1 - 0.09 12.1 14.9 0.12 11.7 10.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Macoilin PF09726.4 EKG17159.1 - 1 7.5 12.2 1.3 7.2 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 EKG17159.1 - 4.7 5.1 9.2 5.5 4.9 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Xpo1 PF08389.7 EKG17160.1 - 5.6e-32 110.6 1.1 7.7e-30 103.7 0.4 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EKG17160.1 - 2.5e-06 27.2 0.1 9.7e-06 25.4 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EKG17160.1 - 5.6e-05 23.3 2.9 0.0014 18.8 0.0 4.3 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EKG17160.1 - 6.2e-05 23.3 5.4 0.0082 16.6 0.0 6.2 7 1 0 7 7 7 1 HEAT-like repeat HEAT PF02985.17 EKG17160.1 - 0.0055 16.6 0.3 3.2 8.0 0.0 4.3 3 0 0 3 3 3 1 HEAT repeat LSM PF01423.17 EKG17161.1 - 1.3e-15 56.7 0.2 1.6e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EKG17161.1 - 0.093 12.1 0.2 0.52 9.7 0.0 2.1 3 0 0 3 3 3 0 PhnA protein 5-FTHF_cyc-lig PF01812.15 EKG17162.1 - 3e-31 108.6 0.0 3.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EKG17163.1 - 1.1e-71 240.5 0.1 1.4e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal F-box-like PF12937.2 EKG17165.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKG17165.1 - 0.21 11.2 1.3 0.87 9.3 0.9 2.1 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EKG17166.1 - 0.031 13.9 0.1 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 F-box-like Pterin_bind PF00809.17 EKG17167.1 - 1.3e-62 210.8 0.0 2.2e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EKG17168.1 - 1e-12 47.9 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 EKG17169.1 - 3.3e-72 243.4 1.6 4e-72 243.1 1.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EKG17169.1 - 1.1e-09 37.6 0.9 1.7e-09 37.0 0.6 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EKG17169.1 - 4.4e-08 32.3 1.9 7.7e-08 31.5 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EKG17169.1 - 0.00012 21.2 0.2 0.00024 20.1 0.1 1.5 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EKG17169.1 - 0.0018 17.2 1.5 0.0031 16.5 1.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.9 EKG17169.1 - 0.076 11.9 0.1 0.21 10.5 0.0 1.7 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Pkinase PF00069.20 EKG17174.1 - 4.6e-60 202.9 0.0 6.3e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17174.1 - 2e-21 76.2 0.0 3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG17174.1 - 3.3e-06 26.2 0.0 5.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG17174.1 - 9.6e-05 22.2 0.3 0.049 13.3 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EKG17174.1 - 0.0022 17.3 0.1 0.0057 16.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family PAS_9 PF13426.1 EKG17174.1 - 0.047 14.0 0.0 1.9 8.8 0.0 3.1 3 0 0 3 3 3 0 PAS domain Seadorna_VP7 PF07387.6 EKG17174.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glyco_hydro_71 PF03659.9 EKG17176.1 - 5.6e-120 400.3 8.4 6.4e-120 400.1 5.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 SnoaL_4 PF13577.1 EKG17177.1 - 2.8e-06 27.2 0.8 7.7e-06 25.8 0.5 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EKG17177.1 - 0.018 15.4 0.3 0.027 14.8 0.2 1.4 1 0 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.11 EKG17179.1 - 3.1e-35 121.5 15.0 3.6e-35 121.3 10.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF791 PF05631.9 EKG17179.1 - 2.3e-05 23.2 1.6 3e-05 22.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EKG17179.1 - 9.8e-05 20.7 5.3 0.00012 20.4 3.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG17179.1 - 0.00015 20.5 15.7 0.00024 19.8 10.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3353 PF11833.3 EKG17179.1 - 0.18 11.2 4.1 0.4 10.1 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Syntaxin-18_N PF10496.4 EKG17180.1 - 1.2e-17 63.4 1.4 4.5e-17 61.6 0.3 2.4 2 1 1 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus TipAS PF07739.8 EKG17180.1 - 0.01 16.1 0.3 0.01 16.1 0.2 2.4 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain Syntaxin PF00804.20 EKG17180.1 - 0.22 11.7 7.4 0.069 13.3 2.6 2.1 2 1 0 2 2 2 0 Syntaxin OEP PF02321.13 EKG17180.1 - 0.69 9.4 7.9 0.077 12.5 1.0 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein Aminotran_1_2 PF00155.16 EKG17181.1 - 4.5e-85 285.7 0.0 5.1e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II BTB PF00651.26 EKG17182.1 - 1.6e-06 28.1 0.0 8e-06 25.8 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain PAP2_3 PF14378.1 EKG17183.1 - 1.2e-19 70.6 14.9 4.3e-17 62.2 1.9 2.6 3 0 0 3 3 3 2 PAP2 superfamily zf-C2H2 PF00096.21 EKG17184.1 - 1.2e-12 47.3 18.8 9.2e-05 22.5 2.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG17184.1 - 1.2e-10 40.9 14.5 0.00041 20.4 1.6 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG17184.1 - 1.2e-07 31.6 21.7 0.00082 19.5 3.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EKG17184.1 - 0.00038 20.2 6.7 0.14 12.0 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG17184.1 - 0.0018 18.3 6.6 0.46 10.6 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.9 EKG17184.1 - 0.039 13.6 5.1 0.14 11.8 3.6 2.0 1 0 0 1 1 1 0 Adenylate kinase, active site lid FYVE PF01363.16 EKG17184.1 - 0.23 11.3 5.7 0.59 10.0 4.0 1.7 1 1 0 1 1 1 0 FYVE zinc finger DUF3505 PF12013.3 EKG17184.1 - 1.3 9.3 9.4 5.3 7.3 0.0 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF3505) zf-HYPF PF07503.7 EKG17184.1 - 1.3 8.4 7.3 7.1 6.1 1.9 2.8 2 0 0 2 2 2 0 HypF finger C1_3 PF07649.7 EKG17184.1 - 6.5 6.8 7.0 1.9 8.6 1.6 2.3 2 0 0 2 2 2 0 C1-like domain AFG1_ATPase PF03969.11 EKG17185.1 - 9.1e-93 310.9 0.0 1.8e-87 293.5 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EKG17185.1 - 0.00012 22.1 0.0 0.22 11.4 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EKG17185.1 - 0.002 18.2 0.0 0.0085 16.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EKG17185.1 - 0.054 13.6 0.4 0.86 9.8 0.0 2.6 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EKG17185.1 - 0.092 12.9 0.6 0.52 10.5 0.0 2.6 4 0 0 4 4 4 0 RNA helicase DUF904 PF06005.7 EKG17186.1 - 0.015 15.5 4.8 0.026 14.8 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Pedibin PF08182.6 EKG17186.1 - 0.68 9.4 4.5 1.4 8.5 2.2 2.1 2 0 0 2 2 2 0 Pedibin/Hym-346 family DUF4337 PF14235.1 EKG17186.1 - 1.2 8.9 6.6 0.69 9.7 3.5 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Pribosyltran PF00156.22 EKG17187.1 - 2.6e-18 65.9 0.6 5.9e-18 64.8 0.3 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EKG17187.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Usp PF00582.21 EKG17187.1 - 0.055 13.6 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family NOGCT PF08155.6 EKG17188.1 - 2.7e-28 97.4 5.1 6.3e-28 96.2 3.6 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EKG17188.1 - 3.3e-27 94.1 0.5 7.5e-27 92.9 0.4 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EKG17188.1 - 1.2e-14 54.2 0.0 2.4e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG17188.1 - 1.6e-06 27.4 0.0 3.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EKG17188.1 - 0.00093 19.6 0.0 0.0029 18.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EKG17188.1 - 0.13 12.0 6.7 3.8 7.3 0.0 3.3 3 1 1 4 4 4 0 Dynamin family AAA_17 PF13207.1 EKG17188.1 - 0.91 10.3 3.8 7.3 7.4 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF3154 PF11351.3 EKG17190.1 - 0.11 12.2 2.6 0.12 12.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) TcpE PF12648.2 EKG17190.1 - 0.15 12.1 0.2 0.15 12.1 0.1 3.8 4 0 0 4 4 4 0 TcpE family VirB8 PF04335.8 EKG17190.1 - 0.61 9.6 3.5 6.1 6.3 0.5 2.5 2 0 0 2 2 2 0 VirB8 protein Reticulon PF02453.12 EKG17191.1 - 4.1e-38 130.6 2.6 4.7e-38 130.4 0.8 1.9 2 0 0 2 2 2 1 Reticulon 5_nucleotid PF05761.9 EKG17191.1 - 0.08 11.4 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 5' nucleotidase family DUF883 PF05957.8 EKG17191.1 - 0.1 12.9 4.3 0.068 13.5 0.9 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EKG17191.1 - 0.85 10.0 4.8 0.8 10.1 0.6 2.4 2 0 0 2 2 2 0 YtxH-like protein adh_short PF00106.20 EKG17192.1 - 1.9e-15 57.1 0.0 3.4e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG17192.1 - 1.1e-07 31.8 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG17192.1 - 3.3e-06 26.8 0.0 4.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG17192.1 - 0.0037 16.7 0.0 0.0049 16.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG17192.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Nol1_Nop2_Fmu PF01189.12 EKG17193.1 - 6.5e-27 94.6 0.0 1.7e-16 60.4 0.0 4.7 4 1 0 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EKG17193.1 - 4.9e-05 23.3 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKG17193.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase adh_short PF00106.20 EKG17194.1 - 8.5e-28 97.3 0.2 1.9e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG17194.1 - 2.1e-08 34.0 0.8 7.8e-08 32.1 0.6 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG17194.1 - 1.3e-07 31.6 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG17194.1 - 1.3e-05 25.2 0.1 3.7e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG17194.1 - 0.0001 21.1 0.1 0.00016 20.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKG17194.1 - 0.00093 18.6 0.1 0.0021 17.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_76 PF03663.9 EKG17195.1 - 1.4e-13 50.9 0.4 1.7e-13 50.7 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RRM_1 PF00076.17 EKG17196.1 - 1.2e-05 24.7 0.0 3.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EKG17196.1 - 0.0012 18.8 0.1 0.006 16.6 0.0 2.1 1 1 0 1 1 1 1 PWI domain RRM_6 PF14259.1 EKG17196.1 - 0.045 13.7 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S21 PF01165.15 EKG17197.1 - 3.1e-15 55.3 3.0 3.1e-15 55.3 2.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S21 SWIRM PF04433.12 EKG17199.1 - 2.5e-13 49.9 0.0 3.6e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 EKG17199.1 - 1.4e-10 40.5 3.6 2.6e-10 39.6 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EKG17199.1 - 5.5e-07 29.5 0.0 1.6e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PGI PF00342.14 EKG17200.1 - 2.9e-218 725.1 0.7 3.7e-218 724.8 0.5 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.20 EKG17200.1 - 7.6e-69 231.7 0.0 1.1e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17200.1 - 3.6e-33 114.7 0.0 5.4e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EKG17200.1 - 6.2e-10 39.4 0.5 2e-09 37.7 0.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EKG17200.1 - 0.0023 16.9 0.0 0.0041 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MTP18 PF10558.4 EKG17202.1 - 1.4e-67 226.2 0.0 1.8e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 EKG17203.1 - 7.3e-31 106.0 0.1 7.9e-31 105.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) AA_kinase PF00696.23 EKG17204.1 - 2.4e-28 99.3 2.1 3.2e-28 98.9 0.6 1.8 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.15 EKG17204.1 - 5.8e-16 57.9 0.0 1.5e-15 56.6 0.0 1.7 1 1 0 1 1 1 1 PUA domain Peptidase_M76 PF09768.4 EKG17205.1 - 2.1e-31 108.6 0.0 2.6e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EKG17205.1 - 0.009 15.6 2.0 0.016 14.8 0.6 1.8 2 0 0 2 2 2 1 SprT-like family DUF2268 PF10026.4 EKG17205.1 - 0.069 12.5 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Pkinase PF00069.20 EKG17206.1 - 2.5e-65 220.2 0.0 3.1e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17206.1 - 5.1e-43 147.0 0.0 6.1e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG17206.1 - 2e-07 30.2 0.0 1.9e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EKG17206.1 - 0.00041 19.4 0.1 0.00065 18.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EKG17206.1 - 0.017 14.4 0.1 0.033 13.5 0.1 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EKG17206.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 EKG17207.1 - 1.7e-78 262.0 0.3 2e-78 261.8 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family COesterase PF00135.23 EKG17208.1 - 2.9e-84 283.7 0.0 4.2e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG17208.1 - 6.5e-09 35.6 0.1 5.3e-08 32.6 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG17208.1 - 0.0003 20.0 0.0 0.0005 19.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family WD40 PF00400.27 EKG17209.1 - 3.1e-21 74.4 2.6 2.1e-05 24.1 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Imp-YgjV PF10688.4 EKG17210.1 - 0.089 12.2 0.8 0.12 11.7 0.5 1.3 1 0 0 1 1 1 0 Bacterial inner membrane protein Glycos_transf_4 PF00953.16 EKG17211.1 - 4e-24 85.2 6.3 4e-24 85.2 4.4 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 ECM11 PF15463.1 EKG17212.1 - 1.1e-33 116.4 4.9 1.1e-33 116.4 3.4 3.2 3 1 0 3 3 3 1 Extracellular mutant protein 11 F-box PF00646.28 EKG17213.1 - 3e-07 29.9 0.3 6e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKG17213.1 - 1.7e-06 27.6 0.4 3.6e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like Aconitase PF00330.15 EKG17214.1 - 4e-143 477.2 0.1 4.4e-143 477.1 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF2786 PF10979.3 EKG17215.1 - 3.2e-09 36.3 0.3 7.3e-09 35.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) COX16 PF14138.1 EKG17215.1 - 1.1 9.4 4.6 0.4 10.8 0.5 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 GDE_C PF06202.9 EKG17217.1 - 0.0029 16.3 0.3 0.015 14.0 0.2 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase DUF1772 PF08592.6 EKG17218.1 - 2.5e-10 40.2 0.1 3.6e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF1219 PF06755.7 EKG17218.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) Amidohydro_2 PF04909.9 EKG17219.1 - 2.6e-38 132.1 0.4 3.3e-38 131.8 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase PTS_EIIB PF00367.15 EKG17219.1 - 0.013 14.7 0.3 0.029 13.6 0.2 1.7 1 0 0 1 1 1 0 phosphotransferase system, EIIB PAS_3 PF08447.6 EKG17219.1 - 0.02 14.9 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 PAS fold DUF4091 PF13320.1 EKG17220.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) HTH_23 PF13384.1 EKG17221.1 - 2.1e-05 23.9 0.1 8.8e-05 22.0 0.0 2.0 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.1 EKG17221.1 - 0.0025 17.3 0.1 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EKG17221.1 - 0.0043 17.0 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_29 PF13551.1 EKG17221.1 - 0.0067 16.5 0.1 0.015 15.4 0.0 1.7 1 1 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EKG17221.1 - 0.027 13.9 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Mga PF08280.6 EKG17221.1 - 0.031 14.0 0.1 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF4648 PF15505.1 EKG17221.1 - 0.086 13.0 0.2 0.24 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4648) Lipase_GDSL_2 PF13472.1 EKG17222.1 - 2e-08 34.5 3.9 2e-08 34.5 2.7 1.6 1 1 1 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EKG17222.1 - 2.8e-06 27.3 0.3 1.3e-05 25.1 0.2 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 EKG17223.1 - 5.2e-35 120.8 18.1 5.2e-35 120.8 12.6 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 EKG17224.1 - 8.6e-48 162.9 0.0 1.2e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EKG17226.1 - 7.4e-22 77.4 0.0 4.7e-11 41.9 0.0 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Amino_oxidase PF01593.19 EKG17227.1 - 9.3e-36 123.8 0.1 1.1e-35 123.5 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF3728 PF12528.3 EKG17227.1 - 0.15 12.4 0.2 0.72 10.2 0.1 2.2 2 0 0 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) Rad4 PF03835.10 EKG17228.1 - 3e-33 114.2 0.0 1e-32 112.5 0.0 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EKG17228.1 - 2e-28 97.9 0.1 3.6e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EKG17228.1 - 7.5e-20 70.2 0.1 1.9e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EKG17228.1 - 6.2e-18 64.8 0.2 3.3e-17 62.5 0.2 2.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EKG17228.1 - 0.0086 16.2 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily BAG PF02179.11 EKG17229.1 - 1.4e-16 60.2 0.1 2.3e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EKG17229.1 - 0.0026 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKG17229.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HHH_4 PF14490.1 EKG17230.1 - 0.049 13.3 0.1 0.88 9.3 0.0 2.2 1 1 1 2 2 2 0 Helix-hairpin-helix containing domain DSPc PF00782.15 EKG17231.1 - 2.4e-26 91.9 0.0 1.1e-25 89.8 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKG17231.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_L4 PF00573.17 EKG17232.1 - 6.9e-42 143.0 1.0 9.4e-42 142.5 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EKG17232.1 - 5e-25 87.1 1.4 5e-25 87.1 0.9 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Daxx PF03344.10 EKG17233.1 - 0.11 11.0 5.8 0.12 10.8 4.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF3359 PF11839.3 EKG17233.1 - 0.6 10.4 3.3 0.98 9.8 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3359) PPP4R2 PF09184.6 EKG17233.1 - 1.8 8.0 6.6 2.2 7.7 4.6 1.1 1 0 0 1 1 1 0 PPP4R2 Ank_4 PF13637.1 EKG17234.1 - 7.8e-19 67.6 0.0 8.8e-10 38.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG17234.1 - 2.3e-18 66.3 0.0 5.8e-15 55.4 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG17234.1 - 4.6e-16 58.4 0.1 1.6e-09 37.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EKG17234.1 - 1.4e-15 56.2 0.0 3.8e-09 35.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EKG17234.1 - 1.5e-11 43.3 0.0 1.8e-07 30.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Acetyltransf_1 PF00583.19 EKG17235.1 - 2.3e-12 46.7 0.0 3.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKG17235.1 - 9.9e-11 41.2 0.0 1.5e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EKG17235.1 - 1.6e-10 41.0 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG17235.1 - 2.3e-05 24.4 0.0 2.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG17235.1 - 0.00014 21.7 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain YcfA PF07927.7 EKG17235.1 - 0.099 12.5 0.0 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 YcfA-like protein SKIP_SNW PF02731.10 EKG17236.1 - 1.2e-67 226.3 4.9 1.2e-67 226.3 3.4 2.6 2 0 0 2 2 2 1 SKIP/SNW domain Raftlin PF15250.1 EKG17236.1 - 1.8 7.0 7.2 2.8 6.3 5.0 1.2 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.1 EKG17236.1 - 9.1 5.9 12.5 1.6 8.4 5.8 1.8 2 0 0 2 2 2 0 Protein Family FAM60A MSP1_C PF07462.6 EKG17237.1 - 0.037 12.4 3.4 0.058 11.7 2.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CtnDOT_TraJ PF07863.6 EKG17238.1 - 1.7 9.1 4.8 0.73 10.3 1.5 1.7 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon 2OG-FeII_Oxy_2 PF13532.1 EKG17239.1 - 8.8e-14 51.7 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EKG17239.1 - 2.6e-06 27.6 0.0 8.2e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.1 EKG17240.1 - 1.6e-16 60.5 0.0 2.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EKG17240.1 - 3.3e-16 59.8 0.0 5e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EKG17240.1 - 0.0001 22.8 0.0 0.00012 22.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain F-box-like PF12937.2 EKG17241.1 - 1.2e-10 40.9 0.1 2.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EKG17241.1 - 2.1e-10 39.9 3.8 0.031 13.9 0.0 5.9 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EKG17241.1 - 7.1e-10 37.9 18.5 3.4 8.0 0.0 9.7 11 0 0 11 11 11 3 Leucine Rich repeat F-box PF00646.28 EKG17241.1 - 3.4e-08 32.9 0.1 1.2e-07 31.1 0.1 2.1 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EKG17241.1 - 5.5e-07 29.2 8.2 0.2 11.4 0.0 4.7 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EKG17241.1 - 0.0067 16.3 19.5 4.1 7.8 0.2 8.5 6 2 0 6 6 6 1 Leucine Rich Repeat PRANC PF09372.5 EKG17241.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 PRANC domain K_oxygenase PF13434.1 EKG17243.1 - 1.4e-12 47.2 0.0 6.6e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EKG17243.1 - 1.7e-11 44.6 0.0 7.3e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG17243.1 - 1e-09 37.1 0.0 7.6e-06 24.3 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EKG17243.1 - 0.00014 21.8 0.0 0.0019 18.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SnoaL_4 PF13577.1 EKG17244.1 - 3.5e-11 43.1 0.1 6.1e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_2 PF00891.13 EKG17245.1 - 5.1e-36 124.0 0.1 9.3e-36 123.2 0.1 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EKG17245.1 - 0.0031 17.2 0.0 0.0068 16.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF336 PF03928.9 EKG17247.1 - 1.3e-20 73.5 0.0 1.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) AA_permease PF00324.16 EKG17248.1 - 1.1e-74 251.4 34.2 1.4e-74 251.2 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG17248.1 - 1.5e-21 76.4 37.2 1.7e-21 76.2 25.8 1.0 1 0 0 1 1 1 1 Amino acid permease Lon_C PF05362.8 EKG17249.1 - 4.6e-58 195.8 0.0 9.4e-58 194.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EKG17249.1 - 2.6e-34 118.7 0.0 7.1e-34 117.2 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EKG17249.1 - 8.5e-22 77.7 0.0 3.3e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG17249.1 - 5.9e-07 29.2 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKG17249.1 - 1.2e-06 28.5 0.0 3.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EKG17249.1 - 5e-06 26.0 0.0 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.6 EKG17249.1 - 7e-06 24.9 0.0 0.00014 20.6 0.0 2.3 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.1 EKG17249.1 - 6.2e-05 23.1 0.1 0.0015 18.6 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG17249.1 - 0.00011 22.9 0.1 0.00065 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EKG17249.1 - 0.00018 20.6 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKG17249.1 - 0.0003 20.8 1.0 0.0038 17.2 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EKG17249.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.20 EKG17249.1 - 0.016 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 EKG17249.1 - 0.021 14.7 0.4 0.17 11.7 0.0 2.7 3 0 0 3 3 3 0 Shikimate kinase IstB_IS21 PF01695.12 EKG17249.1 - 0.032 13.6 0.3 0.087 12.2 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EKG17249.1 - 0.043 14.1 5.0 0.08 13.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EKG17249.1 - 0.047 13.8 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 EKG17249.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKG17249.1 - 0.053 12.7 0.1 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKG17249.1 - 6.1 7.1 7.8 0.64 10.3 0.0 3.0 3 1 0 3 3 3 0 ABC transporter Glyco_hydro_16 PF00722.16 EKG17250.1 - 2.2e-10 40.1 0.1 2.2e-10 40.1 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Prok-RING_2 PF14445.1 EKG17251.1 - 0.24 11.3 2.7 0.34 10.9 0.9 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Aconitase PF00330.15 EKG17253.1 - 3e-132 441.3 0.0 1.6e-131 439.0 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF521 PF04412.8 EKG17253.1 - 0.0022 16.6 0.0 0.0036 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF521) Fungal_trans PF04082.13 EKG17254.1 - 7.4e-23 80.7 2.9 1.3e-22 79.9 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EKG17255.1 - 8.3e-33 113.6 9.0 3.3e-19 68.8 3.8 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG17255.1 - 6.1e-06 25.1 8.2 2e-05 23.5 3.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG17255.1 - 0.002 16.4 0.1 0.0026 16.0 0.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M64 PF09471.5 EKG17256.1 - 0.023 14.3 0.1 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M7 PF02031.11 EKG17256.1 - 0.076 12.7 0.9 0.21 11.3 0.0 2.1 3 0 0 3 3 3 0 Streptomyces extracellular neutral proteinase (M7) family Pkinase PF00069.20 EKG17257.1 - 2.3e-11 43.3 0.0 1.8e-08 33.8 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17257.1 - 5.5e-11 42.0 0.0 5.4e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase p450 PF00067.17 EKG17258.1 - 8.7e-36 123.4 0.0 1e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG17259.1 - 9e-30 103.7 0.2 1.2e-29 103.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG17259.1 - 1.1e-26 94.0 0.0 1.3e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG17259.1 - 4e-12 46.1 0.1 5.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EKG17259.1 - 0.01 15.6 0.2 0.03 14.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG17259.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EKG17259.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MBOAT PF03062.14 EKG17260.1 - 2.1e-31 109.2 18.0 4.6e-31 108.1 12.3 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family LPAM_1 PF08139.7 EKG17260.1 - 7.3 6.9 7.4 42 4.5 1.1 3.0 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site Adaptin_N PF01602.15 EKG17261.1 - 1.4e-141 472.3 1.2 1.7e-141 472.1 0.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EKG17261.1 - 1.4e-23 83.3 0.1 2.8e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EKG17261.1 - 1.6e-06 28.3 2.6 0.021 15.0 0.0 4.9 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EKG17261.1 - 0.00034 20.4 1.1 9.1 6.6 0.0 5.1 4 1 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EKG17261.1 - 0.012 15.4 5.0 0.061 13.1 0.4 3.5 3 2 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 EKG17261.1 - 0.026 14.1 0.4 0.13 11.7 0.1 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 EKG17261.1 - 0.036 14.5 1.7 6.1 7.4 0.0 4.6 4 2 2 6 6 6 0 HEAT-like repeat G-patch_2 PF12656.2 EKG17261.1 - 0.1 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site Arm PF00514.18 EKG17261.1 - 0.33 10.8 5.1 31 4.5 0.0 5.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Glyco_hydro_10 PF00331.15 EKG17262.1 - 4.6e-84 282.1 0.0 5.2e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 KRAB PF01352.22 EKG17263.1 - 0.15 11.5 3.0 0.08 12.4 0.2 1.9 2 0 0 2 2 2 0 KRAB box zf-C2H2 PF00096.21 EKG17263.1 - 0.2 12.0 0.2 0.49 10.8 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG17263.1 - 3 8.3 3.2 2.1 8.8 0.1 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger TIM-br_sig_trns PF09370.5 EKG17264.1 - 1.5e-136 453.7 0.4 1.7e-136 453.5 0.3 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EKG17264.1 - 1.6e-05 24.1 0.1 1.6e-05 24.1 0.1 1.3 2 0 0 2 2 2 1 Nitronate monooxygenase UPF0261 PF06792.6 EKG17265.1 - 2.5e-128 428.0 0.0 8e-128 426.3 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0261) DUF3115 PF11312.3 EKG17265.1 - 0.18 10.5 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) MFS_1 PF07690.11 EKG17268.1 - 3.9e-35 121.1 13.2 4.4e-24 84.8 0.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Arch_ATPase PF01637.13 EKG17270.1 - 2.3e-06 27.5 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EKG17270.1 - 8.5e-06 25.8 0.8 7.3e-05 22.8 0.6 2.2 1 1 0 1 1 1 1 AAA ATPase domain ATP-synt_ab PF00006.20 EKG17270.1 - 0.049 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EKG17270.1 - 0.059 12.7 0.1 0.2 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EKG17270.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EKG17270.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EKG17270.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EKG17270.1 - 0.15 12.5 0.3 1.3 9.5 0.2 2.5 1 1 0 1 1 1 0 Miro-like protein CLU PF13236.1 EKG17271.1 - 9e-82 273.7 0.0 1.9e-81 272.7 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EKG17271.1 - 2.4e-49 167.4 0.0 6.4e-49 166.1 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EKG17271.1 - 3.9e-26 90.9 0.0 1.1e-25 89.5 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EKG17271.1 - 4.5e-18 64.9 3.0 8.5e-09 35.2 0.0 3.8 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EKG17271.1 - 9.7e-14 50.7 0.3 0.0025 17.6 0.0 4.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG17271.1 - 2.3e-05 23.9 3.9 0.017 14.7 0.1 4.3 3 1 1 4 4 4 3 TPR repeat DUF727 PF05303.7 EKG17271.1 - 0.00073 19.2 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_17 PF13431.1 EKG17271.1 - 0.053 13.7 3.5 22 5.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKG17271.1 - 0.17 12.5 3.1 0.35 11.6 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EKG17271.1 - 0.72 9.9 4.0 42 4.4 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4451 PF14616.1 EKG17273.1 - 6.7e-34 116.3 0.4 1.5e-33 115.2 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF822 PF05687.8 EKG17273.1 - 0.01 16.2 2.4 0.035 14.4 1.6 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF822) Golgin_A5 PF09787.4 EKG17273.1 - 7.4 4.9 6.6 11 4.4 4.6 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 UAA PF08449.6 EKG17275.1 - 1.8e-74 250.3 9.9 1.3e-73 247.6 6.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EKG17275.1 - 1e-09 38.4 25.7 2.6e-05 24.2 4.9 3.7 4 1 0 4 4 4 3 EamA-like transporter family Nuc_sug_transp PF04142.10 EKG17275.1 - 2.5e-06 26.7 1.3 0.0031 16.6 0.2 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EKG17275.1 - 0.00036 20.7 20.5 0.016 15.4 4.9 3.1 2 1 1 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EKG17275.1 - 0.0019 17.8 8.5 0.0019 17.8 5.9 2.7 2 2 0 2 2 2 1 Triose-phosphate Transporter family DUF3628 PF12300.3 EKG17276.1 - 0.085 12.8 5.4 0.2 11.6 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) KH_1 PF00013.24 EKG17277.1 - 6.2e-41 137.8 8.3 1.2e-16 60.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EKG17277.1 - 1.1e-29 101.5 12.3 7.9e-12 44.5 0.9 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EKG17277.1 - 8e-11 41.3 9.7 0.0026 17.2 0.4 3.7 3 1 1 4 4 4 3 KH domain KH_4 PF13083.1 EKG17277.1 - 2.6e-08 33.3 3.3 0.055 13.1 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EKG17277.1 - 3.5e-05 23.5 3.8 0.32 10.8 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain dUTPase PF00692.14 EKG17277.1 - 0.04 13.3 0.1 4.5 6.7 0.0 3.0 3 0 0 3 3 3 0 dUTPase ADH_N PF08240.7 EKG17278.1 - 2e-29 101.5 0.5 3.3e-29 100.8 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG17278.1 - 1.7e-17 63.2 0.0 2.5e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EKG17278.1 - 0.0033 17.0 0.3 0.0079 15.8 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 EKG17278.1 - 0.074 13.9 0.0 0.14 13.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 EKG17278.1 - 4.2 6.6 6.7 11 5.3 4.7 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Yippee-Mis18 PF03226.9 EKG17279.1 - 1.6e-23 82.5 0.5 1.8e-23 82.3 0.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.4 EKG17279.1 - 0.027 14.5 1.4 0.084 12.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 EKG17279.1 - 0.027 14.3 1.7 0.072 12.9 1.2 1.7 1 1 0 1 1 1 0 C-terminal domain of RIG-I HNH_5 PF14279.1 EKG17279.1 - 0.036 14.0 0.3 3 7.8 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Evr1_Alr PF04777.8 EKG17279.1 - 0.075 12.9 1.6 1.4 8.9 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF3268 PF11672.3 EKG17279.1 - 0.23 11.5 1.8 1.9 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) TPR_11 PF13414.1 EKG17280.1 - 7.5e-48 160.0 23.0 3.4e-16 58.6 1.6 6.6 3 3 3 6 6 6 5 TPR repeat TPR_1 PF00515.23 EKG17280.1 - 1.4e-36 122.6 18.1 2.5e-06 26.8 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EKG17280.1 - 4.5e-34 113.6 19.7 2.5e-07 30.0 0.2 8.9 8 1 1 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.26 EKG17280.1 - 1.7e-29 101.3 8.6 9.9e-29 98.8 2.7 3.0 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.1 EKG17280.1 - 6.9e-26 90.3 27.1 4.1e-08 33.4 0.6 6.4 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKG17280.1 - 3.3e-25 88.1 17.8 5.1e-06 27.0 0.1 6.4 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKG17280.1 - 1.7e-21 74.7 19.9 9.5e-05 22.7 0.2 9.0 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 EKG17280.1 - 9.3e-20 69.1 14.6 0.0049 16.9 0.0 8.0 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EKG17280.1 - 6.6e-17 59.9 14.6 0.00064 19.3 0.0 8.0 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EKG17280.1 - 7.5e-17 61.0 15.8 6.6e-06 25.9 0.1 6.1 4 2 2 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EKG17280.1 - 1.2e-14 54.1 7.4 1.3e-05 25.2 0.2 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EKG17280.1 - 8.7e-14 50.1 9.1 0.00038 20.0 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 EKG17280.1 - 6.6e-12 45.1 7.7 0.0055 16.5 0.4 5.5 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.1 EKG17280.1 - 1e-10 41.3 15.8 0.0068 16.7 0.0 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_4 PF07721.9 EKG17280.1 - 1.2e-06 28.3 12.1 0.064 13.7 0.2 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKG17280.1 - 2.5e-06 27.2 3.4 0.055 13.3 0.1 4.8 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.12 EKG17280.1 - 8.4e-06 26.1 7.3 0.27 11.5 0.1 4.3 3 2 1 4 4 4 2 Bacterial transcriptional activator domain TPR_10 PF13374.1 EKG17280.1 - 1.9e-05 24.4 9.3 0.0028 17.5 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EKG17280.1 - 0.00062 18.9 14.5 0.13 11.2 0.1 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EKG17280.1 - 0.0017 18.4 20.7 0.24 11.5 0.3 5.7 3 3 1 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EKG17280.1 - 0.0025 17.0 3.3 19 4.5 0.1 5.8 6 0 0 6 6 6 0 SHNi-TPR MIT PF04212.13 EKG17280.1 - 0.0031 17.3 9.5 7.6 6.5 0.1 5.7 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.1 EKG17280.1 - 0.0037 17.5 11.1 2.3 8.4 0.1 4.9 2 2 4 6 6 6 1 Alkyl sulfatase dimerisation ChAPs PF09295.5 EKG17280.1 - 0.0045 15.7 1.8 0.83 8.3 0.0 2.4 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) DUF3597 PF12200.3 EKG17280.1 - 0.014 15.7 0.2 0.014 15.7 0.2 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF3597) RPT PF13446.1 EKG17280.1 - 0.032 13.6 1.3 5.3 6.5 0.0 4.0 4 1 1 5 5 5 0 A repeated domain in UCH-protein PPR PF01535.15 EKG17280.1 - 0.093 12.7 0.3 6.6 6.9 0.0 3.5 3 0 0 3 3 2 0 PPR repeat DUF3856 PF12968.2 EKG17280.1 - 0.2 11.4 9.3 35 4.2 0.2 6.4 5 2 1 6 6 6 0 Domain of Unknown Function (DUF3856) DUF2989 PF11207.3 EKG17280.1 - 5.1 6.5 7.3 51 3.2 0.3 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF2989) DUF3366 PF11846.3 EKG17280.1 - 5.6 6.7 9.4 4.6 7.0 1.5 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3366) K_channel_TID PF07941.6 EKG17282.1 - 0.98 9.6 8.5 2.7 8.3 5.9 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Ferric_reduct PF01794.14 EKG17283.1 - 1.1e-20 73.9 11.2 2.9e-20 72.6 6.0 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EKG17283.1 - 1.4e-18 67.2 0.0 6.3e-16 58.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG17283.1 - 8.7e-17 60.9 0.0 2.4e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain A_deamin PF02137.13 EKG17284.1 - 6.4e-31 107.9 0.0 7.8e-31 107.6 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Dispanin PF04505.7 EKG17284.1 - 0.021 14.3 0.1 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Acylphosphatase PF00708.13 EKG17284.1 - 0.051 13.6 0.9 0.27 11.3 0.0 2.3 2 1 0 2 2 2 0 Acylphosphatase NT-C2 PF10358.4 EKG17285.1 - 2.1e-10 40.2 0.0 2.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SLS PF14611.1 EKG17286.1 - 1.5e-24 86.5 0.1 2.4e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GTP_EFTU PF00009.22 EKG17287.1 - 2.4e-58 196.7 0.1 3.5e-58 196.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKG17287.1 - 1.8e-36 124.2 0.0 5e-36 122.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKG17287.1 - 9.8e-16 57.6 3.6 9.8e-16 57.6 2.5 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EKG17287.1 - 0.0004 20.3 0.4 0.0013 18.7 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EKG17287.1 - 0.0028 17.2 1.7 0.0028 17.2 1.2 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PDZ PF00595.19 EKG17287.1 - 0.11 12.6 0.6 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Fungal_trans PF04082.13 EKG17289.1 - 5.6e-18 64.7 2.5 5.2e-17 61.5 0.8 2.6 2 1 0 3 3 3 2 Fungal specific transcription factor domain TRI12 PF06609.8 EKG17290.1 - 1.5e-29 102.6 30.9 1.8e-29 102.3 21.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG17290.1 - 3.3e-21 75.4 51.3 4.9e-21 74.8 32.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG17290.1 - 3.7e-09 35.6 7.5 3.7e-09 35.6 5.2 3.5 3 1 0 4 4 4 1 Sugar (and other) transporter zf-CCHC PF00098.18 EKG17291.1 - 1.4e-11 43.7 9.7 1.8e-05 24.4 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EKG17291.1 - 5.2e-09 35.6 0.2 9.6e-09 34.7 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EKG17291.1 - 6.4e-07 29.0 6.5 0.00071 19.2 2.0 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EKG17291.1 - 6.1e-06 25.7 0.2 1.5e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EKG17291.1 - 0.0011 18.5 6.0 0.28 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EKG17291.1 - 0.016 14.8 10.3 0.43 10.2 0.4 2.8 3 0 0 3 3 3 0 Zinc knuckle GST_N_3 PF13417.1 EKG17292.1 - 2e-14 53.5 0.0 3.7e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EKG17292.1 - 4.9e-12 45.6 0.0 7.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG17292.1 - 2.2e-11 43.5 0.0 4.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG17292.1 - 2.6e-11 43.5 0.0 1.3e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG17292.1 - 3.7e-09 36.3 0.0 7.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG17292.1 - 3e-08 34.0 0.2 7.2e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Acetyltransf_1 PF00583.19 EKG17295.1 - 0.0041 17.1 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Peptidase_M28 PF04389.12 EKG17296.1 - 8.2e-31 107.1 0.2 2.4e-30 105.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EKG17296.1 - 1.9e-05 24.2 0.0 3.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DnaJ PF00226.26 EKG17298.1 - 6.1e-22 77.1 2.8 1.6e-21 75.7 2.0 1.8 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EKG17299.1 - 1.8e-11 43.8 0.2 2.9e-11 43.1 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG17299.1 - 1.6e-07 31.3 0.0 3.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MR_MLE_C PF13378.1 EKG17300.1 - 6.3e-32 109.8 0.1 1.2e-31 108.9 0.1 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EKG17300.1 - 3.4e-19 68.9 0.0 9.7e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EKG17300.1 - 5.3e-09 36.4 0.0 1.8e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Arrestin_C PF02752.17 EKG17301.1 - 1.1e-11 44.9 0.2 3.5e-11 43.3 0.2 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain bZIP_1 PF00170.16 EKG17302.1 - 5.6e-06 26.2 7.9 5.6e-06 26.2 5.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EKG17302.1 - 0.00086 19.0 7.4 0.00086 19.0 5.1 2.1 2 0 0 2 2 2 1 Basic region leucine zipper rRNA_processing PF08524.6 EKG17302.1 - 0.0043 16.8 7.7 0.01 15.6 5.3 1.6 1 0 0 1 1 1 1 rRNA processing Mit_KHE1 PF10173.4 EKG17302.1 - 0.019 14.7 0.2 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Glutaredoxin2_C PF04399.8 EKG17302.1 - 0.12 12.0 0.5 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain GvpL_GvpF PF06386.6 EKG17302.1 - 0.49 9.9 6.4 0.91 9.0 4.4 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Effector_1 PF04518.7 EKG17302.1 - 1.3 7.9 7.5 0.23 10.4 1.7 2.0 2 0 0 2 2 2 0 Effector from type III secretion system DUF4407 PF14362.1 EKG17302.1 - 6 5.7 13.2 0.56 9.1 3.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Stm1_N PF09598.5 EKG17303.1 - 1.3e-13 51.4 4.6 1.3e-13 51.4 3.2 3.7 4 2 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EKG17303.1 - 1.9e-05 25.1 4.9 1.9e-05 25.1 3.4 3.1 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family DUF3535 PF12054.3 EKG17304.1 - 2.2e-141 471.4 0.6 6.8e-140 466.5 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EKG17304.1 - 2.4e-74 249.8 0.0 3.8e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EKG17304.1 - 3.7e-17 60.8 9.5 0.014 15.3 0.2 9.4 9 0 0 9 9 9 5 HEAT repeat Helicase_C PF00271.26 EKG17304.1 - 3.6e-14 52.3 0.0 7.7e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_2 PF13646.1 EKG17304.1 - 6.8e-08 32.6 10.8 0.0018 18.4 0.0 7.1 8 2 1 9 9 9 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EKG17304.1 - 7.9e-07 29.3 0.1 0.53 10.7 0.0 4.5 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EKG17304.1 - 5.2e-05 22.7 0.6 0.014 14.7 0.0 3.8 4 1 0 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.1 EKG17304.1 - 0.0002 21.7 18.6 0.49 10.9 0.0 8.6 9 0 0 9 9 9 2 HEAT-like repeat DUF1546 PF07571.8 EKG17304.1 - 0.037 14.1 0.2 12 6.0 0.0 4.8 5 1 1 6 6 6 0 Protein of unknown function (DUF1546) AMP-binding PF00501.23 EKG17305.1 - 1.3e-73 247.8 0.0 1.5e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L13 PF00572.13 EKG17306.1 - 4.2e-27 94.7 0.0 7.2e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Fungal_trans PF04082.13 EKG17308.1 - 5.2e-26 91.0 0.1 9.3e-26 90.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17308.1 - 2.3e-11 43.4 12.6 4.1e-11 42.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DOMON PF03351.12 EKG17309.1 - 1.1e-05 25.3 0.7 2.3e-05 24.3 0.5 1.5 1 0 0 1 1 1 1 DOMON domain EB1 PF03271.12 EKG17310.1 - 2.1e-15 56.4 1.5 4.1e-15 55.5 1.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EKG17310.1 - 4.3e-08 33.1 2.1 7e-08 32.4 1.5 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Syja_N PF02383.13 EKG17310.1 - 0.03 13.0 0.1 0.033 12.9 0.0 1.1 1 0 0 1 1 1 0 SacI homology domain Suppressor_APC PF11414.3 EKG17310.1 - 0.039 13.7 0.2 0.086 12.6 0.1 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF1880 PF08976.6 EKG17310.1 - 0.12 12.5 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1880) PX PF00787.19 EKG17311.1 - 5.1e-15 55.2 0.0 8.6e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EKG17311.1 - 1.3e-07 31.2 6.4 2.5e-07 30.2 4.5 1.5 1 0 0 1 1 1 1 SNARE domain GFO_IDH_MocA PF01408.17 EKG17312.1 - 2.5e-10 40.9 0.5 1.1e-09 38.8 0.3 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EKG17312.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase CoA_binding_2 PF13380.1 EKG17312.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 CoA binding domain DHDPS PF00701.17 EKG17313.1 - 2.6e-22 78.7 0.0 3e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family IU_nuc_hydro PF01156.14 EKG17314.1 - 4.5e-79 265.8 0.1 6.3e-55 186.5 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Ferric_reduct PF01794.14 EKG17315.1 - 5.9e-19 68.3 11.2 5.9e-19 68.3 7.8 2.9 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EKG17315.1 - 2e-12 47.3 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG17315.1 - 3.3e-10 39.7 0.0 9.5e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EKG17315.1 - 0.034 14.7 0.0 8.6 6.9 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain PspA_IM30 PF04012.7 EKG17316.1 - 0.018 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 PspA/IM30 family FAD_binding_7 PF03441.9 EKG17318.1 - 2e-26 92.8 1.2 3.3e-26 92.1 0.8 1.4 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase Sugar_tr PF00083.19 EKG17319.1 - 1.1e-36 126.4 13.7 1.3e-36 126.1 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MgtE PF01769.11 EKG17319.1 - 1.3 9.2 7.5 0.22 11.7 1.3 2.2 2 0 0 2 2 2 0 Divalent cation transporter DAO PF01266.19 EKG17320.1 - 2.3e-14 53.0 0.1 3.5e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EKG17321.1 - 2.7e-53 179.7 0.0 3.6e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG17321.1 - 5.9e-19 67.8 0.0 7.3e-19 67.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EKG17321.1 - 3.1e-07 30.3 0.2 7.4e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EKG17321.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 EKG17321.1 - 0.036 13.6 0.0 0.088 12.3 0.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aldolase_II PF00596.16 EKG17323.1 - 6.9e-30 104.0 0.2 9.2e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1338 PF07063.8 EKG17324.1 - 9.7e-36 123.3 0.0 1.2e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Fungal_trans PF04082.13 EKG17325.1 - 4.1e-33 114.3 0.0 1.2e-32 112.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HisKA_2 PF07568.7 EKG17325.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase Man-6-P_recep PF02157.10 EKG17326.1 - 1.5e-11 43.8 0.0 3.2e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 Mannose-6-phosphate receptor CIMR PF00878.13 EKG17326.1 - 3.6e-06 26.7 0.4 0.0043 16.8 0.1 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EKG17326.1 - 0.00012 21.4 5.7 0.00074 18.8 3.5 2.2 1 1 1 2 2 2 1 Autophagy-related protein 27 PBP1_TM PF14812.1 EKG17326.1 - 1.9 8.8 9.2 0.091 13.0 0.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ERG4_ERG24 PF01222.12 EKG17327.1 - 1.7e-168 560.6 7.3 2e-168 560.4 5.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EKG17327.1 - 0.00045 19.6 1.3 0.00092 18.5 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF1793 PF08760.6 EKG17328.1 - 5e-70 234.8 0.3 1.7e-69 233.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Ank_2 PF12796.2 EKG17329.1 - 1.2e-22 80.0 0.0 1.1e-07 32.0 0.0 4.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG17329.1 - 6.9e-17 60.3 0.1 0.0019 17.9 0.0 7.6 7 1 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EKG17329.1 - 8.7e-13 48.4 0.0 0.019 15.4 0.0 6.3 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG17329.1 - 4.8e-12 44.8 0.1 0.0028 17.7 0.0 6.9 7 1 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.1 EKG17329.1 - 1.1e-06 28.6 0.0 0.11 12.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Clr5 PF14420.1 EKG17330.1 - 8.9e-19 67.1 0.0 2e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain FAD_binding_4 PF01565.18 EKG17331.1 - 9.9e-28 96.3 0.2 2.4e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG17331.1 - 0.0012 18.7 0.1 0.0012 18.7 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like MFS_1 PF07690.11 EKG17333.1 - 2.4e-11 42.9 47.1 9.3e-11 41.0 26.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1049 PF06305.6 EKG17333.1 - 0.016 14.6 0.8 0.016 14.6 0.5 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) DUF3818 PF12825.2 EKG17335.1 - 1.9e-43 148.4 0.8 3.6e-25 88.3 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EKG17335.1 - 3.4e-30 104.4 0.0 1.4e-29 102.4 0.0 2.1 2 0 0 2 2 2 1 PX-associated Dyp_perox PF04261.7 EKG17335.1 - 0.03 13.0 0.5 0.054 12.2 0.4 1.3 1 0 0 1 1 1 0 Dyp-type peroxidase family Metal_resist PF13801.1 EKG17335.1 - 0.79 9.7 4.1 6.2 6.8 0.0 3.0 3 1 0 3 3 3 0 Heavy-metal resistance DUF3918 PF13056.1 EKG17336.1 - 0.0068 15.7 0.3 0.015 14.5 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3918) MAPEG PF01124.13 EKG17338.1 - 3.3e-20 72.0 7.1 3.8e-20 71.8 4.9 1.1 1 0 0 1 1 1 1 MAPEG family DUF2637 PF10935.3 EKG17338.1 - 1.1 9.2 10.7 0.42 10.5 4.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) An_peroxidase PF03098.10 EKG17339.1 - 4.7e-90 302.4 0.0 5.8e-73 246.0 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase 3-alpha PF03475.9 EKG17339.1 - 0.11 12.1 0.1 0.47 10.2 0.0 2.1 3 0 0 3 3 3 0 3-alpha domain CVNH PF08881.5 EKG17340.1 - 1.4e-23 83.0 0.5 5.1e-23 81.2 0.1 2.2 2 0 0 2 2 2 1 CVNH domain Sipho_Gp157 PF05565.6 EKG17340.1 - 0.014 14.9 0.2 0.014 14.9 0.2 2.6 3 0 0 3 3 3 0 Siphovirus Gp157 NERD PF08378.6 EKG17340.1 - 0.071 13.3 0.0 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 Nuclease-related domain NPV_P10 PF05531.7 EKG17340.1 - 0.3 11.3 1.5 27 5.0 0.0 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 EKG17340.1 - 8.5 6.4 16.9 18 5.4 0.8 4.2 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain DUF3708 PF12501.3 EKG17340.1 - 9.3 6.0 10.1 1.8 8.3 0.8 2.8 2 1 1 3 3 3 0 Phosphate ATP-binding cassette transporter Fun_ATP-synt_8 PF05933.8 EKG17343.1 - 6.7e-17 61.2 3.5 9.5e-17 60.7 2.4 1.2 1 0 0 1 1 1 1 Fungal ATP synthase protein 8 (A6L) DUF1422 PF07226.6 EKG17343.1 - 0.049 13.3 0.1 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Abhydrolase_6 PF12697.2 EKG17344.1 - 1e-24 87.6 0.0 1.2e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG17344.1 - 8.3e-14 51.6 0.0 1.3e-13 51.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG17344.1 - 1.9e-09 37.4 0.0 3.2e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EKG17344.1 - 2.1e-05 23.2 0.0 2.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EKG17344.1 - 4.3e-05 22.8 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.15 EKG17344.1 - 0.00067 19.1 0.0 0.00094 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DUF2048 PF09752.4 EKG17344.1 - 0.006 15.4 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Abhydrolase_2 PF02230.11 EKG17344.1 - 0.025 14.0 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.15 EKG17344.1 - 0.052 13.7 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EKG17344.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.13 EKG17345.1 - 7.8e-33 113.4 0.0 1.4e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17345.1 - 9.9e-10 38.1 12.7 1.8e-09 37.3 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.8 EKG17345.1 - 2 8.4 8.0 1.6 8.7 0.3 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Catalase PF00199.14 EKG17346.1 - 3.7e-162 539.3 0.3 4.8e-162 539.0 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EKG17346.1 - 1.5e-18 66.4 0.1 2.7e-18 65.5 0.1 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ku PF02735.11 EKG17347.1 - 1.4e-30 106.2 0.0 2.6e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EKG17347.1 - 3.4e-24 85.5 0.3 6.3e-24 84.6 0.0 1.5 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EKG17347.1 - 1.6e-14 53.8 0.0 5e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 EKG17347.1 - 0.00012 22.2 0.0 0.00072 19.6 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain PGAP1 PF07819.8 EKG17348.1 - 1.2e-05 24.9 0.0 2.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EKG17348.1 - 6.5e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG17348.1 - 0.0005 20.0 0.1 0.0012 18.8 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EKG17348.1 - 0.0023 17.2 0.0 0.0049 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EKG17348.1 - 0.0027 17.3 0.0 0.0054 16.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EKG17348.1 - 0.0053 17.0 1.4 0.075 13.2 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain DUF2305 PF10230.4 EKG17348.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) UPF0227 PF05728.7 EKG17348.1 - 0.017 14.8 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF900 PF05990.7 EKG17348.1 - 0.1 11.9 0.0 0.33 10.2 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Reo_sigma1 PF01664.11 EKG17350.1 - 0.038 13.0 0.0 0.045 12.8 0.0 1.0 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 Peptidase_M41 PF01434.13 EKG17351.1 - 4.5e-77 258.3 0.3 1.2e-76 256.9 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 EKG17351.1 - 1.7e-42 144.7 0.0 4.1e-42 143.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EKG17351.1 - 1.8e-10 40.9 0.0 6.8e-10 39.1 0.0 2.1 2 0 0 2 2 1 1 FtsH Extracellular AAA_5 PF07728.9 EKG17351.1 - 4.7e-05 23.1 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG17351.1 - 0.00085 19.4 0.4 0.11 12.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG17351.1 - 0.0024 17.6 0.9 0.019 14.7 0.4 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EKG17351.1 - 0.0074 16.1 0.0 0.071 13.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 EKG17351.1 - 0.0079 14.9 0.1 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EKG17351.1 - 0.015 15.3 0.2 0.19 11.7 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 EKG17351.1 - 0.02 13.9 0.0 0.048 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKG17351.1 - 0.03 15.1 0.0 0.12 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EKG17351.1 - 0.04 13.8 0.0 0.16 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EKG17351.1 - 0.045 12.8 0.3 0.18 10.9 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 EKG17351.1 - 0.072 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EKG17351.1 - 0.13 11.5 1.5 0.52 9.6 0.3 2.5 2 1 1 3 3 3 0 AAA domain Nuc_sug_transp PF04142.10 EKG17353.1 - 8e-09 34.9 0.6 8e-09 34.9 0.4 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EKG17353.1 - 1.5e-07 31.5 24.1 9.8e-06 25.6 1.5 3.3 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.6 EKG17353.1 - 1.4e-06 27.4 9.3 4.1e-06 25.9 6.4 1.7 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EKG17353.1 - 2.1e-06 27.4 17.8 0.0044 16.6 1.9 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EKG17353.1 - 0.0066 16.6 5.3 0.0066 16.6 3.6 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Whi5 PF08528.6 EKG17354.1 - 0.0014 18.1 0.1 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like MTBP_N PF14918.1 EKG17354.1 - 0.058 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 MDM2-binding IncA PF04156.9 EKG17355.1 - 1.6 8.2 6.6 2.8 7.5 4.5 1.3 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EKG17356.1 - 2.7e-35 121.7 25.3 2.7e-35 121.7 17.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.2 EKG17357.1 - 8.9e-89 291.9 21.3 1.6e-13 50.7 0.3 8.8 3 2 8 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EKG17357.1 - 7.9e-57 186.3 26.1 7.7e-07 28.6 0.0 17.3 16 2 1 17 17 17 12 Ankyrin repeat Ank_3 PF13606.1 EKG17357.1 - 5.5e-46 149.9 22.7 4.6e-05 23.2 0.0 17.7 18 1 1 19 19 19 9 Ankyrin repeat Ank_4 PF13637.1 EKG17357.1 - 4.1e-40 135.4 11.7 5.5e-07 29.9 0.1 12.8 7 3 7 15 15 15 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG17357.1 - 1e-30 105.0 10.6 0.00058 20.0 0.0 11.1 11 1 1 12 12 12 7 Ankyrin repeats (many copies) Clr5 PF14420.1 EKG17357.1 - 4e-18 65.0 1.5 7.4e-18 64.1 1.0 1.5 1 0 0 1 1 1 1 Clr5 domain DUF3447 PF11929.3 EKG17357.1 - 0.012 15.3 0.0 30 4.4 0.0 4.7 6 0 0 6 6 6 0 Domain of unknown function (DUF3447) Myb_DNA-binding PF00249.26 EKG17357.1 - 0.071 13.1 0.5 0.97 9.5 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ctr PF04145.10 EKG17358.1 - 0.32 11.0 0.1 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Ctr copper transporter family DUF4098 PF13345.1 EKG17359.1 - 0.042 13.8 0.4 0.8 9.6 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4098) Ank_2 PF12796.2 EKG17360.1 - 3.4e-23 81.7 0.1 4.3e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG17360.1 - 1e-21 76.4 1.0 2.7e-07 30.6 0.1 4.7 2 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EKG17360.1 - 1.3e-16 59.4 0.6 0.00048 19.8 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EKG17360.1 - 1.3e-14 54.2 0.3 0.00013 22.3 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG17360.1 - 2.9e-12 45.5 0.1 0.014 15.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Steroid_dh PF02544.11 EKG17361.1 - 2.2e-14 53.4 0.4 2.7e-14 53.2 0.3 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF998 PF06197.8 EKG17361.1 - 0.048 12.9 4.7 1.1 8.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) PEMT PF04191.8 EKG17361.1 - 0.95 9.6 3.7 0.39 10.8 0.3 2.0 2 1 0 2 2 2 0 Phospholipid methyltransferase Glyco_transf_8 PF01501.15 EKG17362.1 - 2e-32 112.5 0.0 2.9e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EKG17362.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative DUF3638 PF12340.3 EKG17364.1 - 3.3e-90 301.0 0.3 5.8e-90 300.2 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EKG17364.1 - 2.3e-15 55.4 0.0 4.6e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) ATG_C PF09333.6 EKG17365.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 ATG C terminal domain LcnG-beta PF11632.3 EKG17365.1 - 8.5 6.2 11.1 5.1 6.9 2.7 3.2 1 1 2 3 3 3 0 Lactococcin G-beta Sugar_tr PF00083.19 EKG17366.1 - 1.8e-14 53.2 18.9 2.1e-11 43.0 5.0 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG17366.1 - 3.3e-13 49.0 33.9 4e-08 32.3 10.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily IBR PF01485.16 EKG17367.1 - 0.25 11.2 18.5 0.85 9.5 3.3 3.5 3 1 0 3 3 3 0 IBR domain SRP9-21 PF05486.7 EKG17369.1 - 1.3e-28 98.5 0.7 2e-28 97.9 0.5 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Rubella_E2 PF05749.6 EKG17369.1 - 0.12 11.6 0.7 0.13 11.4 0.5 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 DUF1308 PF07000.6 EKG17370.1 - 4.7e-62 209.7 0.0 6.2e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Glyco_hydro_43 PF04616.9 EKG17371.1 - 9.4e-25 87.2 0.4 1.5e-14 53.8 1.3 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Homeobox PF00046.24 EKG17372.1 - 2.9e-19 68.4 5.6 5.8e-19 67.4 3.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EKG17372.1 - 0.00064 19.3 0.6 0.0017 18.0 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF3722 PF12519.3 EKG17373.1 - 3.2e-94 315.0 0.1 4.1e-94 314.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EKG17373.1 - 6.5e-06 25.6 0.0 0.24 10.6 0.0 3.2 4 0 0 4 4 4 2 Eukaryotic porin Ribosomal_L10 PF00466.15 EKG17374.1 - 1.6e-17 63.2 0.1 2.3e-17 62.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF1615 PF07759.7 EKG17374.1 - 0.059 12.1 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) HATPase_c PF02518.21 EKG17375.1 - 7.1e-21 74.0 0.1 1.9e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG17375.1 - 1.8e-16 60.1 0.1 1.5e-12 47.4 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EKG17375.1 - 2e-13 50.1 0.1 8.4e-13 48.1 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EKG17375.1 - 0.012 15.2 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2263 PF10021.4 EKG17376.1 - 6.8e-17 61.8 0.0 1.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) CorA PF01544.13 EKG17377.1 - 1.7e-08 33.9 7.6 4.5e-08 32.4 5.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3543 PF12063.3 EKG17377.1 - 0.017 14.3 0.3 0.021 14.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3543) AAA_11 PF13086.1 EKG17377.1 - 0.021 14.4 0.1 0.026 14.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 EKG17377.1 - 0.052 13.2 1.0 0.084 12.6 0.7 1.3 1 0 0 1 1 1 0 Laminin Domain II TPR_12 PF13424.1 EKG17379.1 - 6.3e-19 67.6 14.0 1e-07 31.8 0.9 6.3 4 1 3 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EKG17379.1 - 7.2e-11 41.1 13.9 0.0055 16.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EKG17379.1 - 1.1e-10 40.5 9.5 0.00029 20.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKG17379.1 - 6.7e-09 35.2 2.9 2.3e-06 27.1 0.1 4.7 4 1 1 5 5 4 2 TPR repeat TPR_10 PF13374.1 EKG17379.1 - 8.7e-08 31.8 15.6 0.00074 19.3 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.17 EKG17379.1 - 1.3e-07 30.8 0.0 9e-06 24.7 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 EKG17379.1 - 9.6e-07 28.1 7.6 0.43 10.4 0.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG17379.1 - 0.00011 22.5 0.7 3.1 8.6 0.7 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 EKG17379.1 - 0.00099 19.3 0.7 0.021 15.2 0.0 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG17379.1 - 0.0068 16.8 0.6 3.6 8.2 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKG17379.1 - 0.013 15.2 6.7 0.059 13.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EKG17379.1 - 0.026 15.1 1.8 19 6.0 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat AAA_22 PF13401.1 EKG17379.1 - 0.042 13.9 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG17379.1 - 0.043 13.8 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain TPR_17 PF13431.1 EKG17379.1 - 0.052 13.7 1.6 1.7 9.0 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat WAC_Acf1_DNA_bd PF10537.4 EKG17379.1 - 0.056 13.6 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Apc3 PF12895.2 EKG17379.1 - 0.24 11.5 2.8 2.7 8.1 0.0 3.2 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Glyco_hydro_28 PF00295.12 EKG17382.1 - 1.6e-103 346.0 21.9 2.1e-103 345.7 15.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EKG17382.1 - 0.00064 19.5 31.8 1.2 8.8 22.1 2.7 1 1 0 1 1 1 1 Right handed beta helix region Lactamase_B PF00753.22 EKG17384.1 - 5.3e-22 78.4 6.1 3e-21 75.9 2.4 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG17384.1 - 1.4e-06 27.9 0.0 2.5e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CoA_binding_2 PF13380.1 EKG17387.1 - 2.3e-24 85.8 0.0 2.9e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Arrestin_N PF00339.24 EKG17388.1 - 3.6e-10 39.8 0.0 1.5e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKG17388.1 - 0.00088 19.3 0.0 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EKG17388.1 - 0.004 16.6 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like CDC73 PF05179.9 EKG17390.1 - 6.2e-41 140.5 0.0 7.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Glyco_hydro_43 PF04616.9 EKG17392.1 - 2.2e-33 115.5 0.3 2.8e-33 115.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PigN PF04987.9 EKG17393.1 - 6.5e-165 549.0 26.1 7.8e-165 548.8 18.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EKG17393.1 - 1.7e-10 40.7 0.1 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EKG17393.1 - 3.9e-09 36.1 0.1 5.3e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EKG17393.1 - 0.00019 20.8 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Coatomer_WDAD PF04053.9 EKG17394.1 - 4e-171 569.6 0.0 7.3e-171 568.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EKG17394.1 - 1.1e-44 148.6 8.7 8e-10 38.2 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EKG17394.1 - 0.00015 20.0 2.3 0.015 13.4 0.1 3.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EKG17394.1 - 0.0056 16.4 0.0 2.1 8.1 0.0 3.2 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region AAA PF00004.24 EKG17396.1 - 3.2e-36 124.4 0.0 5.4e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EKG17396.1 - 5.8e-06 26.2 0.0 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG17396.1 - 1.5e-05 25.8 0.3 7.1e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG17396.1 - 2e-05 24.6 2.5 0.0006 19.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EKG17396.1 - 3e-05 23.1 0.0 5.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EKG17396.1 - 3.3e-05 24.0 0.1 0.00053 20.1 0.1 2.6 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EKG17396.1 - 6.9e-05 22.3 1.5 0.035 13.4 0.1 2.9 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.9 EKG17396.1 - 7.9e-05 22.6 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EKG17396.1 - 9.6e-05 22.1 0.1 0.00063 19.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EKG17396.1 - 0.00018 20.9 0.1 0.00045 19.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EKG17396.1 - 0.00035 20.4 0.0 0.00067 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EKG17396.1 - 0.00072 18.7 0.2 0.0018 17.4 0.1 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EKG17396.1 - 0.00083 19.4 0.0 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EKG17396.1 - 0.001 19.2 0.0 0.0026 17.9 0.0 1.8 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.7 EKG17396.1 - 0.0026 17.4 0.0 0.01 15.4 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 EKG17396.1 - 0.0032 17.7 0.1 0.018 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EKG17396.1 - 0.004 17.1 0.4 0.0077 16.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EKG17396.1 - 0.0047 16.0 0.0 0.0096 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EKG17396.1 - 0.0063 16.2 0.0 0.026 14.2 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 EKG17396.1 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EKG17396.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 EKG17396.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EKG17396.1 - 0.04 13.4 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 EKG17396.1 - 0.044 12.4 0.0 0.098 11.3 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EKG17396.1 - 0.05 12.4 0.3 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 EKG17396.1 - 0.053 12.4 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.7 EKG17396.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Arch_ATPase PF01637.13 EKG17396.1 - 0.074 12.7 0.0 0.29 10.8 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EKG17396.1 - 0.12 12.0 0.2 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Guanylate_kin PF00625.16 EKG17396.1 - 0.13 11.7 0.0 0.84 9.0 0.0 2.3 3 0 0 3 3 3 0 Guanylate kinase SKI PF01202.17 EKG17396.1 - 0.15 11.8 1.5 0.25 11.1 0.0 2.1 3 0 0 3 3 2 0 Shikimate kinase KaiC PF06745.8 EKG17396.1 - 0.16 11.0 0.1 1.2 8.2 0.0 2.1 1 1 1 2 2 2 0 KaiC Viral_helicase1 PF01443.13 EKG17396.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TIM21 PF08294.6 EKG17397.1 - 7.1e-38 129.5 0.0 8.9e-38 129.2 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EKG17397.1 - 8.1e-05 22.1 0.0 0.0002 20.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Tannase PF07519.6 EKG17399.1 - 8.4e-132 440.2 2.0 1.1e-131 439.8 1.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase CBM_4_9 PF02018.12 EKG17400.1 - 4.6e-14 52.5 5.7 4.6e-14 52.5 4.0 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain Peptidase_M35 PF02102.10 EKG17402.1 - 8e-07 28.0 0.4 9.3e-07 27.8 0.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family CARDB PF07705.6 EKG17402.1 - 0.05 13.6 0.1 0.058 13.4 0.1 1.2 1 0 0 1 1 1 0 CARDB Phlebovirus_G2 PF07245.6 EKG17406.1 - 0.0035 15.6 0.0 0.0044 15.3 0.0 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G2 DUF3176 PF11374.3 EKG17407.1 - 4.9e-28 97.2 1.8 1.2e-27 95.9 1.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3188 PF11384.3 EKG17407.1 - 0.035 13.6 0.0 0.12 11.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Pal1 PF08316.6 EKG17408.1 - 1.4e-45 155.1 1.4 1.4e-45 155.1 1.0 2.0 3 0 0 3 3 3 1 Pal1 cell morphology protein Med31 PF05669.7 EKG17409.1 - 1e-35 121.5 0.6 1.3e-35 121.2 0.4 1.0 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.13 EKG17410.1 - 1.2e-19 69.6 3.7 1.2e-19 69.6 2.6 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.2 EKG17410.1 - 9e-06 25.4 6.8 0.013 15.2 0.6 2.7 2 1 0 2 2 2 2 Transposase zinc-ribbon domain RNA_POL_M_15KD PF02150.11 EKG17410.1 - 6.2e-05 22.6 4.1 0.0084 15.7 0.1 3.0 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit C1_4 PF07975.7 EKG17410.1 - 0.022 14.7 5.6 0.91 9.5 0.2 2.7 2 2 0 2 2 2 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.6 EKG17410.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like PhnA_Zn_Ribbon PF08274.7 EKG17410.1 - 0.042 13.6 0.1 0.042 13.6 0.1 2.8 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zinc_ribbon_5 PF13719.1 EKG17410.1 - 0.046 13.3 10.9 3.3 7.3 0.5 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EKG17410.1 - 0.071 12.8 11.5 6.1 6.6 0.7 4.2 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_S21 PF01165.15 EKG17410.1 - 0.12 11.7 1.4 0.21 11.0 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 Baculo_LEF5_C PF11792.3 EKG17410.1 - 0.26 10.7 0.3 0.26 10.7 0.2 1.8 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 EKG17410.1 - 0.44 10.4 0.1 0.44 10.4 0.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-Mss51 PF13824.1 EKG17410.1 - 0.5 10.2 5.8 0.6 9.9 0.1 2.6 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-H2C2_2 PF13465.1 EKG17410.1 - 0.7 10.2 12.9 1 9.7 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain IBR PF01485.16 EKG17410.1 - 1.7 8.6 11.7 6.9 6.6 3.3 3.0 2 2 0 2 2 2 0 IBR domain DUF1470 PF07336.6 EKG17413.1 - 0.0073 16.6 9.1 0.018 15.3 6.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1470) APG6 PF04111.7 EKG17413.1 - 0.49 9.3 12.0 0.61 9.0 8.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Phage_GPO PF05929.6 EKG17413.1 - 3.1 6.9 8.0 4.1 6.5 5.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CENP-Q PF13094.1 EKG17413.1 - 3.2 7.7 15.9 5.9 6.8 11.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 EKG17413.1 - 4.8 6.0 10.7 6.3 5.6 7.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Aldo_ket_red PF00248.16 EKG17414.1 - 3e-56 190.3 0.0 3.5e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fork_head PF00250.13 EKG17417.1 - 5.3e-34 116.1 0.2 9.7e-34 115.2 0.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EKG17417.1 - 7.6e-09 35.5 0.0 1.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain VID27 PF08553.5 EKG17417.1 - 2 6.5 4.5 3.1 5.9 3.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein HCO3_cotransp PF00955.16 EKG17418.1 - 4.6e-73 246.6 12.4 1.4e-41 142.7 4.0 2.0 1 1 1 2 2 2 2 HCO3- transporter family ADH_N PF08240.7 EKG17419.1 - 1.7e-28 98.5 0.3 3.1e-28 97.6 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG17419.1 - 6.7e-08 32.1 0.1 1.3e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EKG17419.1 - 1.8e-05 24.2 0.2 5.1e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EKG17419.1 - 0.0056 15.2 0.3 0.027 12.9 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Abhydrolase_3 PF07859.8 EKG17420.1 - 5.3e-15 55.5 0.2 8.3e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EKG17420.1 - 2.7e-05 22.9 0.0 3.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EKG17420.1 - 0.00082 19.1 0.2 0.001 18.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Epimerase PF01370.16 EKG17422.1 - 4.3e-17 62.3 0.0 8.7e-17 61.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG17422.1 - 2e-14 52.9 0.0 3.7e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG17422.1 - 4.7e-14 52.8 0.3 1.1e-13 51.6 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EKG17422.1 - 7.1e-11 41.5 0.1 3e-05 23.0 0.0 2.5 3 0 0 3 3 3 2 Male sterility protein NmrA PF05368.8 EKG17422.1 - 1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EKG17422.1 - 8.2e-07 29.0 0.2 1.7e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG17422.1 - 0.00015 21.4 0.7 0.0012 18.4 0.5 2.1 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EKG17422.1 - 0.0017 17.4 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 EKG17422.1 - 0.0023 18.4 0.0 0.0044 17.5 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 EKG17422.1 - 0.0032 16.3 0.0 0.005 15.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EKG17422.1 - 0.0065 15.3 0.3 0.26 10.1 0.0 2.5 2 1 1 3 3 3 1 RmlD substrate binding domain NAD_binding_2 PF03446.10 EKG17422.1 - 0.064 13.0 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.15 EKG17422.1 - 0.066 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CDC45 PF02724.9 EKG17423.1 - 8.8e-225 747.4 0.0 1e-224 747.2 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF3533 PF12051.3 EKG17424.1 - 2.4e-88 296.4 17.3 2.9e-88 296.2 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PCI_Csn8 PF10075.4 EKG17424.1 - 0.0052 16.5 0.1 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF2512 PF10710.4 EKG17424.1 - 4 6.8 10.6 12 5.3 4.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) DUF1014 PF06244.7 EKG17425.1 - 1.4e-23 83.3 2.7 3.3e-23 82.2 1.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Kinetocho_Slk19 PF12709.2 EKG17425.1 - 0.046 13.8 0.0 0.046 13.8 0.0 2.1 2 1 0 2 2 2 0 Central kinetochore-associated CHASE3 PF05227.8 EKG17425.1 - 0.054 13.1 4.6 0.17 11.5 3.2 1.7 1 1 0 1 1 1 0 CHASE3 domain MscS_porin PF12795.2 EKG17426.1 - 0.00011 21.5 220.8 0.13 11.5 16.8 8.4 1 1 7 9 9 9 7 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.4 EKG17426.1 - 0.0023 17.7 227.8 0.31 10.8 10.9 11.1 1 1 10 11 11 11 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EKG17426.1 - 0.0038 15.9 21.5 0.0038 15.9 14.9 9.4 1 1 8 9 9 9 4 Spc7 kinetochore protein GAS PF13851.1 EKG17426.1 - 0.0092 15.2 197.0 0.036 13.2 12.3 9.1 1 1 6 8 8 8 6 Growth-arrest specific micro-tubule binding Filament PF00038.16 EKG17426.1 - 0.023 14.1 205.7 0.028 13.9 34.8 8.9 1 1 6 7 7 7 0 Intermediate filament protein Reo_sigmaC PF04582.7 EKG17426.1 - 0.071 12.2 116.0 0.027 13.6 11.2 8.6 1 1 7 8 8 8 0 Reovirus sigma C capsid protein IncA PF04156.9 EKG17426.1 - 0.3 10.6 216.7 0.015 14.8 25.4 9.7 1 1 9 10 10 10 0 IncA protein Myosin_tail_1 PF01576.14 EKG17426.1 - 1.3 6.6 245.6 0.0012 16.7 102.1 4.3 1 1 3 4 4 4 0 Myosin tail AAA_13 PF13166.1 EKG17426.1 - 3 6.1 198.5 0.27 9.6 21.3 7.5 1 1 6 7 7 7 0 AAA domain Pox_A_type_inc PF04508.7 EKG17426.1 - 10 6.2 49.3 3.2 7.7 0.1 14.9 16 1 1 17 17 17 0 Viral A-type inclusion protein repeat MFS_1 PF07690.11 EKG17427.1 - 5.6e-39 133.8 22.4 8.8e-39 133.1 15.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2085 PF09858.4 EKG17427.1 - 2.5 8.2 8.3 0.14 12.2 0.5 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2085) Ras PF00071.17 EKG17428.1 - 6.1e-57 191.5 0.0 9.8e-57 190.8 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKG17428.1 - 2.8e-20 73.0 0.0 4.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG17428.1 - 2.9e-14 52.6 0.0 9e-14 51.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG17428.1 - 1.6e-07 30.6 0.0 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EKG17428.1 - 1.2e-06 28.1 0.0 3.5e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EKG17428.1 - 6.5e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EKG17428.1 - 0.002 18.1 0.4 0.0044 17.0 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EKG17428.1 - 0.012 14.7 0.0 0.59 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKG17428.1 - 0.028 14.5 0.0 0.087 12.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain DUF2868 PF11067.3 EKG17428.1 - 4.9 6.2 6.9 2.4 7.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) zf-BED PF02892.10 EKG17429.1 - 0.019 14.6 1.3 0.043 13.5 0.9 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 EKG17429.1 - 0.025 14.9 2.8 0.071 13.4 1.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG17429.1 - 0.035 14.4 3.4 0.035 14.4 2.4 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Scs3p PF10261.4 EKG17431.1 - 1.1e-67 227.5 0.5 1.4e-67 227.2 0.4 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Varsurf_PPLC PF03490.8 EKG17432.1 - 0.051 13.2 0.7 0.68 9.6 0.0 2.7 2 1 1 3 3 3 0 Variant-surface-glycoprotein phospholipase C P16-Arc PF04699.9 EKG17433.1 - 9.1e-31 106.9 0.0 1.1e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) LMBR1 PF04791.11 EKG17436.1 - 4.6e-34 117.8 2.7 6.1e-34 117.4 1.9 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein IncA PF04156.9 EKG17436.1 - 0.0046 16.5 0.4 0.0046 16.5 0.3 2.1 2 1 0 2 2 2 1 IncA protein Glutaredoxin PF00462.19 EKG17437.1 - 1.1e-17 63.7 0.2 2.6e-16 59.3 0.1 2.2 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EKG17437.1 - 0.00027 21.1 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 EKG17437.1 - 0.033 14.4 0.1 0.05 13.8 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 EKG17437.1 - 0.041 13.4 0.1 0.9 9.0 0.0 2.1 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EKG17437.1 - 0.064 13.2 0.5 3.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin GST_N_3 PF13417.1 EKG17437.1 - 0.14 12.3 0.1 0.57 10.4 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pkinase PF00069.20 EKG17438.1 - 4.9e-45 153.7 0.0 1.8e-42 145.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17438.1 - 2.2e-26 92.4 0.0 8.6e-26 90.5 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG17438.1 - 0.0061 15.5 0.0 0.22 10.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like DEAD PF00270.24 EKG17439.1 - 2e-41 141.2 0.0 4.4e-40 136.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG17439.1 - 2.4e-27 94.5 0.1 6.4e-27 93.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKG17439.1 - 4.5e-06 25.6 0.0 6.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EKG17439.1 - 0.0032 17.3 0.0 0.0082 15.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Fungal_trans PF04082.13 EKG17440.1 - 1.4e-26 92.8 0.0 2.5e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17440.1 - 1.8e-09 37.3 10.9 2.7e-09 36.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EKG17441.1 - 2.4e-10 39.7 0.1 2.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 EKG17442.1 - 5.8e-16 57.7 0.3 2.2e-09 36.6 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EKG17442.1 - 2.7e-08 33.5 0.1 1.5e-05 24.7 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.7 EKG17442.1 - 2.4e-06 26.8 0.1 0.048 13.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EKG17442.1 - 6.5e-05 22.6 0.4 0.035 13.7 0.0 2.2 2 0 0 2 2 2 2 Cupin CENP-C_C PF11699.3 EKG17442.1 - 0.00017 21.5 0.2 0.14 12.1 0.1 2.4 2 0 0 2 2 2 2 Mif2/CENP-C like AraC_binding_2 PF14525.1 EKG17442.1 - 0.00045 19.8 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 2 AraC-binding-like domain FdtA PF05523.6 EKG17442.1 - 0.0015 18.0 0.0 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 WxcM-like, C-terminal MannoseP_isomer PF01050.13 EKG17442.1 - 0.002 17.7 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase p450 PF00067.17 EKG17443.1 - 5.9e-12 44.8 0.0 7.2e-12 44.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Bunya_NS-S PF01104.12 EKG17443.1 - 0.016 14.6 0.1 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s TAT_signal PF10518.4 EKG17444.1 - 9.3 6.5 7.7 2.5 8.3 0.5 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence MFS_1 PF07690.11 EKG17446.1 - 9.5e-31 106.7 34.9 1.1e-30 106.5 24.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EKG17446.1 - 0.00013 21.9 3.0 0.00028 20.8 0.2 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1228) M20_dimer PF07687.9 EKG17447.1 - 2.9e-09 36.6 0.1 6.5e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EKG17447.1 - 0.00013 21.5 5.4 0.00022 20.8 3.8 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Fungal_trans PF04082.13 EKG17447.1 - 0.00022 20.2 0.7 0.00036 19.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_2 PF00891.13 EKG17449.1 - 4.9e-32 111.0 0.0 6.1e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Cu-oxidase_3 PF07732.10 EKG17451.1 - 1e-41 141.3 4.8 1.4e-39 134.4 0.1 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG17451.1 - 3.6e-39 133.4 8.2 1.5e-35 121.7 0.3 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG17451.1 - 3.8e-27 95.1 0.5 3.1e-25 88.9 0.1 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EKG17451.1 - 0.036 13.9 0.0 4.3 7.2 0.0 2.9 2 1 0 2 2 2 0 Cupredoxin-like domain E1-E2_ATPase PF00122.15 EKG17452.1 - 1.3e-31 109.4 0.1 2.1e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 EKG17452.1 - 2.2e-11 43.7 0.1 7.2e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase PF00702.21 EKG17452.1 - 1.2e-08 35.6 0.1 2.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG17452.1 - 0.13 12.4 0.0 0.57 10.3 0.0 2.1 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3425 PF11905.3 EKG17454.1 - 1.5e-09 37.8 0.0 3.7e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) ketoacyl-synt PF00109.21 EKG17457.1 - 3.1e-74 249.6 0.0 4.6e-74 249.0 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG17457.1 - 3.7e-36 123.5 0.0 8.8e-35 119.1 0.0 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 EKG17457.1 - 5.2e-05 22.8 0.5 0.00072 19.1 0.1 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EKG17457.1 - 0.00042 19.3 0.0 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain KR PF08659.5 EKG17458.1 - 2e-68 229.6 1.2 7.1e-68 227.8 0.8 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EKG17458.1 - 4.3e-61 207.0 0.1 6.7e-61 206.3 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EKG17458.1 - 7.1e-54 182.2 1.6 7.1e-54 182.2 1.1 2.9 3 1 0 3 3 2 1 short chain dehydrogenase PS-DH PF14765.1 EKG17458.1 - 7.5e-49 166.4 0.2 1.6e-48 165.3 0.1 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EKG17458.1 - 1.6e-19 69.7 0.1 7.3e-19 67.6 0.1 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG17458.1 - 2.6e-12 47.7 1.8 1.1e-10 42.5 0.0 3.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG17458.1 - 6.5e-10 38.7 0.4 2e-09 37.1 0.3 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EKG17458.1 - 1.6e-07 31.4 0.1 4e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EKG17458.1 - 0.00054 19.4 0.3 0.0019 17.7 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG17458.1 - 0.0036 16.2 0.0 0.0061 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ELFV_dehydrog PF00208.16 EKG17458.1 - 0.039 13.5 0.7 3.3 7.2 0.2 2.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NmrA PF05368.8 EKG17458.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.15 EKG17458.1 - 0.28 11.2 1.5 1.4 9.0 0.0 2.7 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAA_hydrolase PF01557.13 EKG17459.1 - 1.4e-53 181.6 0.0 1.8e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyco_hydro_42 PF02449.10 EKG17460.1 - 1.8e-10 40.4 0.0 3.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 EKG17460.1 - 3.7e-08 33.0 0.0 6.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 EKG17460.1 - 0.054 12.5 0.0 0.14 11.1 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 10 Sugar_tr PF00083.19 EKG17461.1 - 5.6e-70 236.1 8.8 7e-70 235.8 6.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG17461.1 - 9e-20 70.6 19.9 7.1e-19 67.7 13.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG17461.1 - 2.4e-06 26.2 8.4 0.0051 15.2 2.0 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EKG17461.1 - 0.1 10.7 8.6 0.013 13.7 2.0 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.10 EKG17461.1 - 0.22 10.1 7.6 0.17 10.5 3.4 1.9 1 1 1 2 2 2 0 PUCC protein DUF939 PF06081.6 EKG17461.1 - 9.2 6.1 9.0 0.63 9.9 0.5 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF939) Fungal_trans PF04082.13 EKG17462.1 - 3.4e-06 26.1 0.1 8e-06 24.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2361 PF10153.4 EKG17465.1 - 6.6e-34 116.5 3.4 6.6e-34 116.5 2.4 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) WD40 PF00400.27 EKG17466.1 - 0.0016 18.2 0.2 11 6.0 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-rbx1 PF12678.2 EKG17466.1 - 0.0052 16.8 3.6 0.0052 16.8 2.5 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EKG17466.1 - 2.7 7.9 13.3 0.25 11.1 4.6 2.8 2 1 0 2 2 2 0 Ring finger domain RRM_1 PF00076.17 EKG17467.1 - 4.5e-16 58.2 0.0 8e-16 57.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG17467.1 - 6.4e-14 51.6 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG17467.1 - 6.9e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKG17467.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif PHD PF00628.24 EKG17468.1 - 4.6e-09 35.8 6.5 7.8e-09 35.1 4.5 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EKG17468.1 - 0.00047 20.3 0.1 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EKG17468.1 - 0.027 14.6 1.4 0.054 13.6 1.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EKG17468.1 - 0.031 14.2 0.2 0.06 13.3 0.2 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain PhyH PF05721.8 EKG17469.1 - 8.4e-11 42.3 0.2 7.5e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EKG17469.1 - 7.2e-07 28.0 0.2 0.0034 15.9 0.1 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Glyco_hydro_3 PF00933.16 EKG17470.1 - 1.6e-89 299.8 0.0 2.2e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG17470.1 - 2.3e-57 194.1 0.2 1.9e-56 191.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG17470.1 - 2.9e-17 62.3 0.1 5.5e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.13 EKG17471.1 - 3.8e-14 52.2 2.9 5.9e-14 51.5 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arrestin_N PF00339.24 EKG17472.1 - 3.8e-07 30.0 0.4 3e-06 27.1 0.3 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKG17472.1 - 0.0018 18.3 0.1 0.3 11.2 0.1 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SidE PF12252.3 EKG17472.1 - 0.21 8.8 0.0 0.27 8.4 0.0 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein Ndufs5 PF10200.4 EKG17474.1 - 0.0019 18.1 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX6B PF02297.12 EKG17474.1 - 0.014 15.3 0.8 0.016 15.2 0.3 1.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Dioxygenase_C PF00775.16 EKG17475.1 - 2.2e-54 183.5 0.0 3.2e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EKG17475.1 - 4.5e-12 45.7 0.1 7.2e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EKG17475.1 - 0.00016 21.6 0.0 0.0017 18.3 0.0 2.3 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain TPP_enzyme_N PF02776.13 EKG17476.1 - 3.5e-37 127.5 0.0 6.1e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EKG17476.1 - 1.7e-22 79.6 0.0 5e-22 78.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EKG17476.1 - 4.5e-14 52.2 0.2 1.2e-11 44.4 0.0 2.6 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PIG-L PF02585.12 EKG17476.1 - 0.082 13.4 0.9 0.35 11.3 0.3 2.2 1 1 1 2 2 2 0 GlcNAc-PI de-N-acetylase Glyco_hydro_47 PF01532.15 EKG17477.1 - 1.7e-131 439.0 0.0 1.9e-131 438.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Chromate_transp PF02417.10 EKG17479.1 - 3.3e-51 173.2 36.4 8.8e-29 100.2 10.0 2.5 3 0 0 3 3 3 2 Chromate transporter CcmH PF03918.9 EKG17479.1 - 0.12 11.3 0.1 0.4 9.6 0.0 1.9 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Pkinase PF00069.20 EKG17480.1 - 5.3e-55 186.3 0.0 8.3e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Na_H_Exchanger PF00999.16 EKG17480.1 - 4.6e-37 127.4 37.0 6.9e-37 126.8 25.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase_Tyr PF07714.12 EKG17480.1 - 3.8e-30 104.8 0.0 6e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG17480.1 - 0.00022 20.2 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG17480.1 - 0.0071 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SK_channel PF03530.9 EKG17480.1 - 0.018 14.8 6.5 0.14 11.9 0.5 3.4 3 0 0 3 3 3 0 Calcium-activated SK potassium channel Methyltransf_2 PF00891.13 EKG17481.1 - 5.4e-19 68.3 0.0 8e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FeoC PF09012.5 EKG17481.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator DUF4066 PF13278.1 EKG17483.1 - 2.4e-09 36.6 0.0 3.7e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EKG17483.1 - 3.7e-05 23.2 0.0 6.6e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family 4HBT PF03061.17 EKG17484.1 - 8.7e-09 35.3 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EKG17484.1 - 0.00015 20.7 0.0 0.00019 20.4 0.0 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase DUF4265 PF14085.1 EKG17484.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Fungal_trans PF04082.13 EKG17485.1 - 7.2e-05 21.7 0.1 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EKG17486.1 - 3e-67 227.1 0.0 3.9e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Grp1_Fun34_YaaH PF01184.14 EKG17487.1 - 4.2e-11 42.5 13.5 5.1e-11 42.2 9.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family 7TM_GPCR_Sri PF10327.4 EKG17487.1 - 0.0094 14.9 0.2 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Sri Bax1-I PF01027.15 EKG17487.1 - 0.47 10.0 16.5 0.036 13.6 8.3 1.5 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF3493 PF11998.3 EKG17487.1 - 3.2 7.7 6.1 3.9 7.4 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3493) Glyco_transf_90 PF05686.7 EKG17488.1 - 1e-30 106.7 0.4 1.4e-30 106.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EKG17488.1 - 0.00017 21.7 0.2 0.00042 20.5 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 RTA1 PF04479.8 EKG17491.1 - 2.6e-41 141.5 3.7 3.9e-41 140.9 2.6 1.2 1 0 0 1 1 1 1 RTA1 like protein PalH PF08733.5 EKG17491.1 - 0.073 11.8 1.2 0.1 11.4 0.1 1.8 1 1 0 1 1 1 0 PalH/RIM21 LigD_N PF13298.1 EKG17491.1 - 0.087 12.9 0.2 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) DUF3397 PF11877.3 EKG17491.1 - 0.15 12.0 8.4 2.7 8.0 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3397) Peptidase_U4 PF03419.8 EKG17491.1 - 0.83 8.6 4.2 0.2 10.6 0.8 1.6 2 0 0 2 2 2 0 Sporulation factor SpoIIGA COesterase PF00135.23 EKG17492.1 - 2e-59 201.7 0.0 2.7e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG17492.1 - 2.6e-06 27.1 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG17492.1 - 0.002 17.3 0.1 0.0032 16.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AMP-binding PF00501.23 EKG17493.1 - 1.5e-30 105.9 0.1 1.6e-30 105.8 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme APH PF01636.18 EKG17494.1 - 1.1e-10 41.7 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKG17494.1 - 0.025 13.7 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Fructosamin_kin PF03881.9 EKG17494.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.6 1 1 0 1 1 1 0 Fructosamine kinase DUF1446 PF07287.6 EKG17495.1 - 1.1e-80 270.7 0.0 3.1e-56 190.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1446) Oxidored_FMN PF00724.15 EKG17496.1 - 6.2e-90 301.6 0.0 7.2e-90 301.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.20 EKG17498.1 - 2.6e-24 85.9 0.0 3.7e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG17498.1 - 4.3e-10 39.7 0.0 5.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG17498.1 - 4.6e-09 36.1 0.0 8.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EKG17498.1 - 0.00048 19.3 0.0 0.00066 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EKG17498.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG17498.1 - 0.025 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EKG17498.1 - 0.1 12.3 0.1 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3425 PF11905.3 EKG17499.1 - 9.8e-24 83.7 0.9 2e-23 82.7 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) SPX PF03105.14 EKG17499.1 - 0.047 13.4 2.6 0.088 12.5 1.8 1.3 1 0 0 1 1 1 0 SPX domain DUF904 PF06005.7 EKG17499.1 - 0.3 11.4 9.3 18 5.7 6.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF2317 PF10079.4 EKG17499.1 - 0.35 9.4 3.4 0.93 8.0 2.4 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) WD40_alt PF14077.1 EKG17499.1 - 1.2 8.7 7.5 0.29 10.7 1.2 2.4 1 1 1 2 2 2 0 Alternative WD40 repeat motif NYD-SP28_assoc PF14775.1 EKG17499.1 - 1.7 8.4 9.6 1.3 8.7 1.0 3.1 1 1 2 3 3 3 0 Sperm tail C-terminal domain V_ATPase_I PF01496.14 EKG17499.1 - 1.9 6.2 3.9 2.6 5.8 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.10 EKG17499.1 - 2.1 8.2 17.7 0.36 10.6 0.9 3.2 2 1 1 3 3 3 0 Basic region leucine zipper FliT PF05400.8 EKG17499.1 - 2.4 8.5 14.5 8.6 6.8 4.0 2.4 1 1 1 2 2 2 0 Flagellar protein FliT bZIP_1 PF00170.16 EKG17499.1 - 4 7.4 15.9 37 4.3 4.4 2.9 1 1 1 2 2 2 0 bZIP transcription factor COesterase PF00135.23 EKG17501.1 - 6.6e-16 58.1 1.4 7.8e-16 57.8 0.9 1.0 1 0 0 1 1 1 1 Carboxylesterase family Yqai PF09466.5 EKG17502.1 - 0.064 13.2 0.1 0.69 9.9 0.0 2.6 2 1 0 2 2 2 0 Hypothetical protein Yqai DLH PF01738.13 EKG17503.1 - 3.6e-29 101.6 0.0 4.1e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG17503.1 - 5.1e-07 29.5 0.0 7.3e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cupin_3 PF05899.7 EKG17504.1 - 0.14 11.5 3.3 0.17 11.3 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF861) DUF1180 PF06679.7 EKG17504.1 - 0.18 11.6 0.9 0.4 10.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pirin_C PF05726.8 EKG17504.1 - 0.35 10.9 2.6 0.56 10.3 0.5 2.0 1 1 1 2 2 2 0 Pirin C-terminal cupin domain SpoA PF01052.15 EKG17504.1 - 0.4 10.2 2.9 0.59 9.7 0.1 2.2 2 0 0 2 2 2 0 Surface presentation of antigens (SPOA) Alkyl_sulf_dimr PF14863.1 EKG17505.1 - 6.7e-59 198.1 0.1 1.6e-58 196.8 0.0 1.7 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation Alkyl_sulf_C PF14864.1 EKG17505.1 - 4.8e-34 117.0 0.0 9.1e-34 116.1 0.0 1.5 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B PF00753.22 EKG17505.1 - 1.9e-28 99.4 0.3 3.9e-28 98.4 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG17505.1 - 3.7e-06 26.6 0.0 7.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain TPR_16 PF13432.1 EKG17505.1 - 2.6e-05 24.7 0.2 0.00011 22.8 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKG17505.1 - 0.00055 19.5 0.1 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 TPR repeat Lactamase_B_3 PF13483.1 EKG17505.1 - 0.0047 16.6 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SCP2 PF02036.12 EKG17505.1 - 0.0098 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family TPR_19 PF14559.1 EKG17505.1 - 0.1 12.9 0.1 0.36 11.2 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Thioredoxin PF00085.15 EKG17506.1 - 4.1e-11 42.4 0.0 4.4e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EKG17506.1 - 0.00082 19.3 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 EKG17506.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_8 PF13905.1 EKG17506.1 - 0.017 15.2 0.0 2.5 8.2 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like YTH PF04146.10 EKG17506.1 - 0.032 13.8 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 YT521-B-like domain Thioredoxin_2 PF13098.1 EKG17506.1 - 0.036 14.2 0.0 0.32 11.2 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EKG17506.1 - 0.037 13.8 0.0 0.054 13.2 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin domain Glyco_hydro_67N PF03648.9 EKG17507.1 - 0.1 12.6 0.1 0.36 10.8 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus DUF883 PF05957.8 EKG17508.1 - 0.02 15.2 17.5 1.1 9.7 0.0 5.8 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF883) XH PF03469.9 EKG17508.1 - 0.11 12.1 16.7 0.2 11.2 0.0 4.8 1 1 3 4 4 4 0 XH domain Apolipoprotein PF01442.13 EKG17508.1 - 0.12 11.8 19.6 1.6 8.1 11.9 3.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain ArsC PF03960.10 EKG17508.1 - 1.1 9.3 5.7 3.8 7.6 0.8 3.5 3 2 1 4 4 4 0 ArsC family MADF_DNA_bdg PF10545.4 EKG17508.1 - 1.5 9.0 5.6 0.61 10.3 0.1 2.9 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DrrA_P4M PF14860.1 EKG17508.1 - 2.7 7.7 11.3 1.2 8.8 0.4 3.0 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Glyco_hydro_53 PF07745.8 EKG17509.1 - 0.035 12.8 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Glyco_hydro_17 PF00332.13 EKG17509.1 - 0.22 10.4 2.1 0.65 8.9 1.5 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 17 Tyrosinase PF00264.15 EKG17511.1 - 4.3e-50 170.9 0.5 5.8e-50 170.5 0.3 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase CAP PF00188.21 EKG17512.1 - 5.9e-21 75.2 0.8 5.9e-21 75.2 0.6 2.1 1 1 1 2 2 2 1 Cysteine-rich secretory protein family MSP1_C PF07462.6 EKG17512.1 - 1.4 7.2 3.3 1.5 7.1 2.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Period_C PF12114.3 EKG17512.1 - 1.5 8.4 17.0 2.1 7.9 11.8 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MFS_1 PF07690.11 EKG17513.1 - 4.9e-32 111.0 34.2 4.9e-32 111.0 23.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0182 PF03699.8 EKG17513.1 - 0.041 11.8 0.1 0.074 10.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) COesterase PF00135.23 EKG17514.1 - 1.5e-92 311.0 0.1 8.3e-83 278.9 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG17514.1 - 4.8e-11 42.6 0.1 8e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG17514.1 - 0.00056 19.6 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family UcrQ PF02939.11 EKG17515.1 - 2.9e-25 87.8 0.2 4.2e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 UcrQ family 7TM_GPCR_Srv PF10323.4 EKG17515.1 - 0.097 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Fungal_trans PF04082.13 EKG17516.1 - 0.044 12.6 2.2 1.6 7.5 0.0 2.8 3 0 0 3 3 3 0 Fungal specific transcription factor domain Pectate_lyase PF03211.8 EKG17517.1 - 1.3e-66 224.1 3.0 1.6e-66 223.8 2.1 1.0 1 0 0 1 1 1 1 Pectate lyase DUF1680 PF07944.7 EKG17518.1 - 7.1e-113 377.6 0.0 9.8e-113 377.1 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_2 PF13249.1 EKG17518.1 - 0.03 14.7 0.0 3.7 7.9 0.0 2.9 3 0 0 3 3 3 0 Prenyltransferase-like Sugar_tr PF00083.19 EKG17519.1 - 3.1e-50 171.0 14.4 1.2e-43 149.4 2.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG17519.1 - 1.6e-22 79.7 21.7 7.1e-14 51.2 6.4 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_39 PF01229.12 EKG17520.1 - 7.3e-06 24.6 0.1 1e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Cellulase-like PF12876.2 EKG17520.1 - 0.022 15.2 0.4 0.6 10.5 0.1 2.8 3 0 0 3 3 3 0 Sugar-binding cellulase-like Fungal_trans PF04082.13 EKG17521.1 - 1.6e-09 37.0 2.1 2.5e-09 36.4 0.1 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EKG17522.1 - 2.7e-14 53.5 0.1 3.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG17522.1 - 6.5e-06 25.8 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG17522.1 - 0.00014 21.6 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EKG17522.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Gly_kinase PF02595.10 EKG17523.1 - 4.3e-121 404.1 8.2 5.3e-121 403.8 5.7 1.0 1 0 0 1 1 1 1 Glycerate kinase family MFS_1 PF07690.11 EKG17524.1 - 1.2e-14 53.8 0.8 1.5e-14 53.4 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG17524.1 - 2.5e-08 32.9 1.5 5e-08 31.9 1.1 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Arrestin_N PF00339.24 EKG17528.1 - 0.0015 18.3 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF2293 PF10056.4 EKG17529.1 - 0.12 12.3 3.1 0.13 12.2 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Prp31_C PF09785.4 EKG17530.1 - 5e-47 159.3 3.4 7.3e-47 158.8 0.5 2.2 2 0 0 2 2 2 1 Prp31 C terminal domain Nop PF01798.13 EKG17530.1 - 1.9e-42 144.1 0.1 4.2e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EKG17530.1 - 1.6e-21 75.8 0.1 5e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 NOSIC (NUC001) domain TPR_14 PF13428.1 EKG17531.1 - 2.9e-26 89.5 17.3 0.00069 20.0 0.0 12.1 6 3 7 13 13 13 5 Tetratricopeptide repeat HAT PF02184.11 EKG17531.1 - 9.5e-23 79.6 73.8 2.1e-13 49.7 2.7 14.3 15 0 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EKG17531.1 - 1.9e-22 79.3 0.2 2.4e-05 24.5 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EKG17531.1 - 9.2e-20 70.7 14.8 0.0042 17.7 0.0 8.2 8 2 1 10 10 9 6 Tetratricopeptide repeat Suf PF05843.9 EKG17531.1 - 1.3e-16 61.1 20.8 8.5e-06 25.7 0.1 6.0 3 2 2 5 5 5 4 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EKG17531.1 - 4.9e-12 45.0 0.3 0.0022 18.0 0.0 5.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG17531.1 - 2.1e-09 36.8 12.0 0.053 13.1 0.0 6.3 7 0 0 7 7 6 3 TPR repeat TPR_2 PF07719.12 EKG17531.1 - 2.6e-08 33.1 21.4 0.075 12.9 0.0 10.2 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG17531.1 - 7.8e-06 25.3 10.1 5.6 6.9 0.0 8.1 7 2 2 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG17531.1 - 1.8e-05 24.8 18.9 13 6.4 0.0 8.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.1 EKG17531.1 - 1.8e-05 24.5 21.5 0.086 12.7 0.0 8.4 9 1 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 EKG17531.1 - 9.5e-05 21.5 20.4 0.0083 15.2 0.3 5.5 2 1 4 6 6 6 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKG17531.1 - 0.00018 21.2 10.5 2.2 8.2 0.0 6.2 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat U3_assoc_6 PF08640.6 EKG17531.1 - 0.00031 20.4 27.5 0.0045 16.7 1.6 7.9 6 2 2 9 9 9 1 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.1 EKG17531.1 - 0.0026 17.4 13.6 2.1 8.3 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EKG17531.1 - 0.0027 17.2 6.4 45 3.8 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat B12-binding_2 PF02607.12 EKG17531.1 - 0.0041 17.1 0.2 0.85 9.6 0.1 4.1 3 0 0 3 3 3 1 B12 binding domain TPR_9 PF13371.1 EKG17531.1 - 0.068 13.0 9.0 2.3 8.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EKG17531.1 - 0.098 11.5 0.1 0.098 11.5 0.1 6.8 3 3 5 9 9 9 0 NRDE-2, necessary for RNA interference DHO_dh PF01180.16 EKG17532.1 - 1.3e-10 40.7 0.0 1.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FA_desaturase PF00487.19 EKG17533.1 - 9.4e-18 64.5 16.8 2e-17 63.4 11.6 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EKG17533.1 - 4.2e-14 52.0 0.0 9.2e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.17 EKG17534.1 - 7.5e-63 212.6 0.0 8.6e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 4HBT PF03061.17 EKG17535.1 - 2.2e-10 40.5 0.0 5.1e-10 39.3 0.0 1.6 1 1 1 2 2 2 1 Thioesterase superfamily Rnf-Nqr PF02508.9 EKG17536.1 - 0.056 13.0 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Rnf-Nqr subunit, membrane protein Ion_trans PF00520.26 EKG17538.1 - 4.1e-111 368.9 82.2 1.1e-37 129.2 4.7 5.7 4 2 1 5 5 5 4 Ion transport protein PKD_channel PF08016.7 EKG17538.1 - 0.0015 16.9 0.7 0.0015 16.9 0.5 6.9 6 1 1 7 7 7 4 Polycystin cation channel EF-hand_1 PF00036.27 EKG17538.1 - 0.0021 17.2 0.0 0.0063 15.7 0.0 1.9 1 0 0 1 1 1 1 EF hand JSRP PF15312.1 EKG17538.1 - 0.048 13.6 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein EF-hand_6 PF13405.1 EKG17538.1 - 0.084 12.8 0.0 0.4 10.6 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain GalP_UDP_transf PF01087.17 EKG17538.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Sporozoite_P67 PF05642.6 EKG17539.1 - 0.96 7.2 8.8 0.28 8.9 4.3 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen PAP1 PF08601.5 EKG17539.1 - 4.2 6.9 10.7 5.4 6.6 7.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 OTT_1508_deam PF14441.1 EKG17540.1 - 4.7e-11 42.6 0.1 8.4e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Activator_LAG-3 PF11498.3 EKG17540.1 - 0.069 11.8 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Glyco_hydro_31 PF01055.21 EKG17541.1 - 2.4e-126 422.1 0.3 2.9e-126 421.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG17541.1 - 2.2e-05 24.2 1.0 0.00019 21.2 0.0 2.9 3 1 0 3 3 3 1 Galactose mutarotase-like Form_Nir_trans PF01226.12 EKG17542.1 - 8.6e-75 250.8 16.1 9.8e-75 250.6 11.2 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter UPF0029 PF01205.14 EKG17543.1 - 1.8e-16 59.8 0.0 9.3e-16 57.4 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF3439 PF11921.3 EKG17543.1 - 0.31 10.8 2.8 0.58 9.9 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EKG17543.1 - 2.5 7.8 13.4 0.15 11.8 5.2 2.0 2 1 0 2 2 2 0 Mucin-like glycoprotein SSP160 PF06933.6 EKG17543.1 - 8.3 4.2 7.2 12 3.7 5.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cu-oxidase_2 PF07731.9 EKG17545.1 - 1.4e-38 131.5 6.2 8.6e-37 125.7 0.2 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG17545.1 - 1.7e-38 131.0 3.3 1.7e-38 131.0 2.3 2.4 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EKG17545.1 - 1.9e-34 118.8 2.1 2.4e-33 115.2 0.0 3.0 3 0 0 3 3 3 1 Multicopper oxidase MFS_1 PF07690.11 EKG17546.1 - 1.1e-13 50.7 28.2 1.3e-09 37.2 10.9 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF3469 PF11952.3 EKG17546.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) GMC_oxred_N PF00732.14 EKG17547.1 - 7.9e-56 189.3 0.0 4.1e-36 124.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG17547.1 - 2.1e-35 122.1 0.0 4.4e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EKG17547.1 - 9e-05 22.4 0.0 0.00026 20.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG17547.1 - 0.0001 21.3 0.3 0.0004 19.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG17547.1 - 0.0009 18.1 0.5 0.032 13.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EKG17547.1 - 0.0026 16.7 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EKG17547.1 - 0.015 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EKG17547.1 - 0.056 11.9 0.0 0.15 10.4 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EKG17547.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.17 EKG17548.1 - 7.3e-36 123.6 0.0 3.2e-28 98.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 AA_permease_2 PF13520.1 EKG17549.1 - 4e-14 52.0 32.9 4.5e-14 51.8 22.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG17549.1 - 0.00043 18.7 24.2 0.00057 18.3 16.8 1.1 1 0 0 1 1 1 1 Amino acid permease VIT1 PF01988.14 EKG17549.1 - 0.083 12.3 2.2 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 VIT family Fungal_trans PF04082.13 EKG17550.1 - 5.1e-06 25.5 1.1 5.1e-06 25.5 0.8 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17550.1 - 0.15 12.0 12.5 0.38 10.6 8.6 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CorA PF01544.13 EKG17551.1 - 4.4e-05 22.6 0.3 7.7e-05 21.8 0.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PAD PF03068.10 EKG17551.1 - 0.072 11.5 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) NFRKB_winged PF14465.1 EKG17551.1 - 0.23 11.2 2.6 1.3 8.8 0.1 3.0 3 0 0 3 3 3 0 NFRKB Winged Helix-like CwfJ_C_1 PF04677.10 EKG17552.1 - 1.7e-12 47.0 0.0 3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FumaraseC_C PF10415.4 EKG17552.1 - 0.081 12.9 0.1 32 4.7 0.0 3.4 3 0 0 3 3 3 0 Fumarase C C-terminus ATP_bind_1 PF03029.12 EKG17553.1 - 8.3e-75 251.3 0.0 1.1e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EKG17553.1 - 6.4e-05 21.8 0.1 0.22 10.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 EKG17553.1 - 0.00012 21.5 0.0 0.022 14.2 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EKG17553.1 - 0.00024 21.2 0.0 0.0008 19.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKG17553.1 - 0.00038 19.9 0.3 0.00063 19.2 0.1 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EKG17553.1 - 0.00059 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EKG17553.1 - 0.00082 19.2 0.4 0.0019 18.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EKG17553.1 - 0.0035 17.0 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 EKG17553.1 - 0.0056 16.6 0.0 0.02 14.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKG17553.1 - 0.0066 16.9 0.0 5.1 7.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKG17553.1 - 0.0068 15.6 0.0 1.6 7.9 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family AAA_17 PF13207.1 EKG17553.1 - 0.0076 17.0 0.0 0.0076 17.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain PRK PF00485.13 EKG17553.1 - 0.012 15.1 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EKG17553.1 - 0.013 14.9 0.0 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 EKG17553.1 - 0.014 14.2 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EKG17553.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EKG17553.1 - 0.021 14.0 0.0 0.53 9.5 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B Zeta_toxin PF06414.7 EKG17553.1 - 0.027 13.5 0.0 0.058 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 EKG17553.1 - 0.034 13.8 0.0 0.095 12.4 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EKG17553.1 - 0.059 12.8 0.1 0.78 9.2 0.0 2.7 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EKG17553.1 - 0.078 12.3 0.0 2.9 7.2 0.0 2.6 3 0 0 3 3 3 0 Ras family AAA_24 PF13479.1 EKG17553.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EKG17553.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain cobW PF02492.14 EKG17553.1 - 0.1 12.0 0.0 0.93 8.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EKG17553.1 - 0.68 10.2 0.0 0.68 10.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 EKG17553.1 - 0.77 8.3 5.2 0.94 8.0 0.0 2.9 3 0 0 3 3 3 0 G-protein alpha subunit U1snRNP70_N PF12220.3 EKG17553.1 - 0.94 9.8 6.9 0.12 12.6 1.5 2.0 2 0 0 2 2 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal JAB PF01398.16 EKG17554.1 - 8.7e-08 31.9 0.1 4e-07 29.7 0.1 2.0 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Methyltransf_31 PF13847.1 EKG17555.1 - 6.8e-24 84.1 0.0 3.1e-13 49.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EKG17555.1 - 7.4e-12 45.6 0.0 1.5e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG17555.1 - 3.3e-10 39.4 0.0 8.1e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EKG17555.1 - 1.4e-09 37.8 0.0 2.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG17555.1 - 2e-09 37.7 0.0 1.1e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG17555.1 - 1.1e-08 35.6 0.0 2.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG17555.1 - 1.5e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG17555.1 - 6.9e-05 23.2 0.0 0.0061 17.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EKG17555.1 - 0.0057 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.8 EKG17555.1 - 0.012 14.7 1.3 0.079 12.0 0.9 2.0 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EKG17555.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Lysozyme_like PF13702.1 EKG17555.1 - 0.037 13.4 0.1 4.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Lysozyme-like SymE_toxin PF08845.5 EKG17555.1 - 0.05 13.4 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Toxin SymE, type I toxin-antitoxin system CMAS PF02353.15 EKG17555.1 - 0.11 11.5 0.0 1.1 8.3 0.0 2.0 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.12 EKG17555.1 - 0.12 11.2 0.0 3.1 6.6 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family FMN_red PF03358.10 EKG17556.1 - 1.8e-23 82.7 0.1 3.3e-23 81.8 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EKG17556.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin-like fold GHBP PF12772.2 EKG17556.1 - 0.058 12.8 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Growth hormone receptor binding NAD_binding_10 PF13460.1 EKG17557.1 - 5.6e-05 23.2 0.8 0.00034 20.6 0.6 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG17557.1 - 0.00013 21.5 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family G-patch_2 PF12656.2 EKG17557.1 - 0.018 14.8 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 DExH-box splicing factor binding site DUF3336 PF11815.3 EKG17558.1 - 2.1e-38 131.0 0.2 8.3e-38 129.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EKG17558.1 - 9.3e-17 61.6 0.5 1.9e-16 60.6 0.1 1.7 2 0 0 2 2 2 1 Patatin-like phospholipase Fungal_trans PF04082.13 EKG17559.1 - 4e-16 58.6 0.0 9.7e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17559.1 - 2.8e-08 33.5 8.8 4.8e-08 32.7 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LPP PF04728.8 EKG17559.1 - 0.54 10.0 3.0 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Pyr_redox_3 PF13738.1 EKG17560.1 - 5.8e-15 55.8 0.1 3.7e-06 27.1 0.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG17560.1 - 1.4e-07 31.4 0.5 4.6e-07 29.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EKG17560.1 - 7.4e-06 24.4 0.0 2.7e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EKG17560.1 - 0.00063 18.7 0.0 0.0018 17.2 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EKG17560.1 - 0.0013 18.7 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EKG17560.1 - 0.0026 17.6 0.0 0.23 11.3 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG17560.1 - 0.0068 15.3 0.4 0.1 11.4 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG17560.1 - 0.007 16.1 0.0 0.04 13.6 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EKG17560.1 - 0.022 13.8 0.2 0.081 12.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EKG17560.1 - 0.073 11.9 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EKG17560.1 - 0.094 11.7 0.1 0.2 10.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EKG17560.1 - 0.19 10.5 2.1 1.3 7.8 1.6 2.0 2 0 0 2 2 2 0 FAD binding domain ABC_tran PF00005.22 EKG17562.1 - 5.4e-46 156.3 0.1 4.2e-22 78.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 EKG17562.1 - 4.9e-21 74.3 8.1 4.9e-21 74.3 5.6 3.1 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 EKG17562.1 - 9.8e-15 55.2 1.3 0.0065 16.4 0.0 4.6 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EKG17562.1 - 1.3e-09 37.6 1.0 0.017 14.3 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EKG17562.1 - 1.6e-07 32.1 0.4 0.024 15.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EKG17562.1 - 2.1e-05 23.9 0.1 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EKG17562.1 - 2.6e-05 24.6 0.0 0.027 14.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EKG17562.1 - 4.8e-05 23.6 0.5 0.2 11.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EKG17562.1 - 0.0001 22.2 0.0 0.04 13.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EKG17562.1 - 0.00012 22.2 0.3 1.1 9.3 0.0 3.2 2 2 0 2 2 2 2 AAA domain DUF258 PF03193.11 EKG17562.1 - 0.00012 21.2 0.0 0.033 13.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EKG17562.1 - 0.00016 20.8 3.1 0.58 9.1 0.0 4.3 4 1 1 5 5 5 1 AAA ATPase domain AAA_23 PF13476.1 EKG17562.1 - 0.00031 21.1 15.5 0.067 13.5 0.0 4.9 5 0 0 5 5 5 2 AAA domain MobB PF03205.9 EKG17562.1 - 0.00077 19.1 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EKG17562.1 - 0.0011 18.9 3.8 0.019 14.9 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain NACHT PF05729.7 EKG17562.1 - 0.0011 18.5 0.1 0.94 9.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EKG17562.1 - 0.0013 18.5 0.1 2.8 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EKG17562.1 - 0.0035 17.5 0.0 2 8.5 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EKG17562.1 - 0.0042 16.9 0.9 0.37 10.5 0.0 3.4 3 0 0 3 3 3 1 Dynamin family AAA_10 PF12846.2 EKG17562.1 - 0.0049 16.3 0.1 3 7.1 0.0 3.3 4 0 0 4 4 4 1 AAA-like domain ArgK PF03308.11 EKG17562.1 - 0.0052 15.5 0.5 2 7.0 0.0 2.6 2 0 0 2 2 2 2 ArgK protein RNA_helicase PF00910.17 EKG17562.1 - 0.015 15.4 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EKG17562.1 - 0.017 15.0 0.0 12 5.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EKG17562.1 - 0.018 14.9 5.6 0.19 11.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 EKG17562.1 - 0.024 14.0 0.0 8.3 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EKG17562.1 - 0.025 14.2 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EKG17562.1 - 0.12 11.8 0.5 8.6 5.7 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EKG17562.1 - 0.13 12.0 0.3 10 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EKG17562.1 - 0.13 11.8 0.1 16 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain NMD3 PF04981.8 EKG17562.1 - 2.2 7.3 3.3 0.81 8.7 0.2 1.7 2 0 0 2 2 1 0 NMD3 family tRNA_synt_1c_R1 PF04558.10 EKG17563.1 - 0.064 12.7 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Lactamase_B PF00753.22 EKG17564.1 - 5.1e-17 62.1 1.1 9.2e-17 61.3 0.8 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EKG17564.1 - 1.2e-05 24.8 0.2 1.6e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_6 PF13174.1 EKG17564.1 - 0.062 13.7 0.0 0.2 12.1 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat AdoHcyase PF05221.12 EKG17566.1 - 8.1e-139 461.0 0.1 9.3e-139 460.8 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EKG17566.1 - 1.4e-83 278.6 2.3 2.1e-83 278.0 1.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EKG17566.1 - 6.7e-07 28.6 0.1 1.7e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EKG17566.1 - 0.001 18.7 0.1 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 EKG17566.1 - 0.0047 16.9 0.1 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 EKG17566.1 - 0.0049 16.2 0.2 0.009 15.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TMEM107 PF14995.1 EKG17566.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein dsrm PF00035.20 EKG17569.1 - 2.2e-08 34.5 0.0 0.00026 21.5 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif FtsJ PF01728.14 EKG17570.1 - 3.8e-16 59.5 0.0 5.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DASH_Dad1 PF08649.5 EKG17570.1 - 2.5 7.8 5.3 1.1 8.9 0.3 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad1 Ribonucleas_3_3 PF14622.1 EKG17571.1 - 3.6e-05 23.7 0.0 6.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ifi-6-16 PF06140.8 EKG17573.1 - 0.0002 21.0 11.4 0.00033 20.3 7.9 1.4 1 1 0 1 1 1 1 Interferon-induced 6-16 family Glyco_hydro_81 PF03639.8 EKG17574.1 - 1.7e-184 614.7 0.2 5.6e-145 484.0 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 81 Ribonucleas_3_3 PF14622.1 EKG17575.1 - 5.3e-11 42.5 0.0 6.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EKG17575.1 - 1.8e-08 34.8 0.0 5e-08 33.3 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain PilX_N PF14341.1 EKG17575.1 - 0.058 13.0 1.8 0.12 12.0 0.4 2.0 2 0 0 2 2 2 0 PilX N-terminal Prefoldin_2 PF01920.15 EKG17577.1 - 1.7e-19 69.5 3.9 2.4e-19 69.0 2.7 1.2 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EKG17577.1 - 0.027 14.1 6.6 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Mito_carr PF00153.22 EKG17577.1 - 0.098 12.3 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial carrier protein Spc7 PF08317.6 EKG17577.1 - 0.11 11.1 5.2 0.2 10.3 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF972 PF06156.8 EKG17577.1 - 0.16 12.3 9.7 6.5 7.1 6.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) BLOC1_2 PF10046.4 EKG17577.1 - 0.17 12.0 0.2 0.17 12.0 0.1 2.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LUC7 PF03194.10 EKG17577.1 - 0.18 11.3 2.2 0.23 10.9 1.5 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Spc24 PF08286.6 EKG17577.1 - 0.29 10.8 5.5 0.38 10.4 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 EKG17577.1 - 0.3 10.9 7.9 0.53 10.1 0.4 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.3 EKG17577.1 - 0.68 9.9 7.0 0.86 9.6 1.9 2.0 1 1 1 2 2 2 0 YlqD protein THOC7 PF05615.8 EKG17577.1 - 0.89 9.8 5.8 3.4 7.9 0.3 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 DUF2681 PF10883.3 EKG17577.1 - 1.1 9.5 5.4 15 5.8 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) BRE1 PF08647.6 EKG17577.1 - 1.3 9.0 7.9 8 6.5 2.1 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4618 PF15397.1 EKG17577.1 - 2.1 7.6 10.8 0.16 11.2 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TBPIP PF07106.8 EKG17577.1 - 2.7 7.4 7.7 0.81 9.2 0.4 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FTA4 PF13093.1 EKG17577.1 - 3.2 7.1 7.3 17 4.7 5.0 1.8 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FlxA PF14282.1 EKG17577.1 - 4.1 7.3 11.1 8.8 6.3 3.3 2.1 2 0 0 2 2 2 0 FlxA-like protein DivIVA PF05103.8 EKG17577.1 - 6.4 6.8 8.2 4.5 7.3 1.0 2.1 2 0 0 2 2 2 0 DivIVA protein HR1 PF02185.11 EKG17577.1 - 7.9 6.2 10.5 9.6 6.0 2.6 2.7 2 1 0 2 2 2 0 Hr1 repeat Ceramidase PF05875.7 EKG17578.1 - 1.5e-102 342.2 7.2 2e-102 341.8 5.0 1.1 1 0 0 1 1 1 1 Ceramidase Gryzun PF07919.7 EKG17579.1 - 1.9e-102 343.3 0.0 2.5e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EKG17579.1 - 5.1e-81 271.8 0.0 4.4e-77 258.9 0.0 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EKG17579.1 - 4.8e-06 26.2 0.0 9.6e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking DUF4352 PF11611.3 EKG17579.1 - 0.074 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) RXT2_N PF08595.6 EKG17580.1 - 2.8e-28 98.5 0.3 7.9e-28 97.1 0.2 1.8 1 0 0 1 1 1 1 RXT2-like, N-terminal Ank_5 PF13857.1 EKG17580.1 - 6.1e-17 61.2 3.1 4.5e-11 42.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) VPS9 PF02204.13 EKG17580.1 - 1.7e-14 53.6 0.0 3.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.1 EKG17580.1 - 8.3e-11 42.1 0.1 0.0014 19.0 0.0 4.1 3 2 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG17580.1 - 1.5e-10 41.3 0.2 2.5e-06 27.7 0.1 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKG17580.1 - 4.2e-07 29.4 0.1 0.045 13.5 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EKG17580.1 - 6.1e-06 25.9 0.2 4.2 7.9 0.0 5.5 5 0 0 5 5 5 1 Ankyrin repeat PX PF00787.19 EKG17580.1 - 8.1e-05 22.3 0.0 0.00028 20.6 0.0 2.0 1 0 0 1 1 1 1 PX domain TPR_11 PF13414.1 EKG17581.1 - 8.4e-21 73.4 5.6 6.4e-18 64.1 1.6 2.2 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKG17581.1 - 9.6e-17 59.8 4.4 2.2e-07 30.1 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKG17581.1 - 1.9e-14 52.3 6.8 2.1e-06 27.2 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKG17581.1 - 1.7e-10 41.2 16.9 3.4e-09 37.1 2.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG17581.1 - 2.4e-08 33.1 0.8 0.00044 19.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG17581.1 - 6.3e-07 29.1 4.2 0.0013 18.8 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKG17581.1 - 1.3e-06 28.2 7.7 0.001 18.9 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKG17581.1 - 1.5e-06 27.5 4.4 0.0039 16.8 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG17581.1 - 1.7e-06 28.1 6.4 0.052 14.1 0.2 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 EKG17581.1 - 3.9e-05 23.4 1.1 0.00011 21.9 0.3 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG17581.1 - 9e-05 22.7 3.0 0.00023 21.4 1.5 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3366 PF11846.3 EKG17581.1 - 0.00087 19.2 1.6 0.0014 18.5 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) BTAD PF03704.12 EKG17581.1 - 0.0014 18.9 1.4 0.12 12.7 0.2 2.4 2 0 0 2 2 2 1 Bacterial transcriptional activator domain XPC-binding PF09280.6 EKG17581.1 - 0.0021 17.4 6.4 0.0021 17.4 4.4 1.8 2 0 0 2 2 2 1 XPC-binding domain TPR_10 PF13374.1 EKG17581.1 - 0.0046 16.8 3.7 0.41 10.6 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG17581.1 - 0.027 14.9 7.7 1.5 9.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EKG17581.1 - 0.029 14.7 0.7 0.77 10.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EKG17581.1 - 0.2 10.3 0.1 0.36 9.5 0.1 1.3 1 0 0 1 1 1 0 Coatomer WD associated region MIT PF04212.13 EKG17581.1 - 2 8.3 6.6 0.37 10.7 0.4 2.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain PUA PF01472.15 EKG17582.1 - 4.6e-13 48.6 0.1 7.1e-12 44.8 0.1 2.1 1 1 0 1 1 1 1 PUA domain Tudor-knot PF11717.3 EKG17583.1 - 0.012 15.3 0.2 0.084 12.5 0.0 2.4 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain CK_II_beta PF01214.13 EKG17584.1 - 7.5e-72 240.6 0.1 9.2e-72 240.4 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Ribosomal_L2_C PF03947.13 EKG17585.1 - 5.8e-46 155.4 1.4 1.2e-45 154.5 0.9 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EKG17585.1 - 1.5e-27 95.3 0.3 2.8e-27 94.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EKG17586.1 - 3.7e-44 149.3 0.3 9.4e-44 148.0 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EKG17586.1 - 1.3e-32 112.1 0.0 2.6e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L10 PF00466.15 EKG17587.1 - 0.0097 15.8 0.0 0.085 12.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 tRNA-synt_2b PF00587.20 EKG17588.1 - 8.7e-31 106.8 0.0 1.4e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKG17588.1 - 2.6e-09 36.9 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Bcl-2 PF00452.14 EKG17588.1 - 0.17 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Glycos_transf_3 PF00591.16 EKG17589.1 - 1.4e-62 211.4 0.0 7.7e-51 172.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EKG17589.1 - 5.6e-10 38.6 0.0 9.9e-10 37.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain CBF PF03914.12 EKG17590.1 - 3.9e-47 159.7 0.0 2.1e-46 157.3 0.0 2.3 1 0 0 1 1 1 1 CBF/Mak21 family Cnd1 PF12717.2 EKG17590.1 - 0.044 13.6 0.9 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 2-Hacid_dh_C PF02826.14 EKG17591.1 - 3.1e-20 72.0 0.0 4.2e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Zn_clus PF00172.13 EKG17593.1 - 4.4e-08 32.9 10.7 7e-08 32.2 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUZ PF12752.2 EKG17594.1 - 0.00024 21.5 10.7 0.00024 21.5 7.4 3.7 3 1 1 4 4 4 1 SUZ domain SUZ-C PF12901.2 EKG17594.1 - 0.0046 16.5 4.3 0.014 14.9 3.0 1.9 1 0 0 1 1 1 1 SUZ-C motif DUF3408 PF11888.3 EKG17594.1 - 0.58 10.0 6.7 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF1682 PF07946.9 EKG17594.1 - 1.8 7.3 10.7 2.6 6.8 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) YbjM PF11045.3 EKG17596.1 - 0.14 11.9 21.0 3.3 7.4 0.2 6.5 6 0 0 6 6 6 0 Putative inner membrane protein of Enterobacteriaceae VBS PF08913.5 EKG17596.1 - 0.38 10.9 1.8 85 3.4 0.1 4.5 3 1 0 3 3 3 0 Vinculin Binding Site Utp12 PF04003.7 EKG17596.1 - 1.4 8.8 35.9 3.7 7.4 0.1 11.2 9 7 5 14 14 14 0 Dip2/Utp12 Family GST_N_3 PF13417.1 EKG17597.1 - 1.4e-25 89.3 0.0 2.7e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EKG17597.1 - 6.2e-15 54.9 0.0 1.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG17597.1 - 2.6e-06 27.4 0.0 4.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG17597.1 - 5.7e-06 26.1 0.2 1.2e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG17597.1 - 0.007 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG17597.1 - 0.037 14.5 0.0 0.079 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EKG17597.1 - 0.04 13.8 0.0 0.084 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Glyco_hydro_71 PF03659.9 EKG17598.1 - 1.6e-58 198.0 5.5 1.9e-58 197.8 3.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Nuc_sug_transp PF04142.10 EKG17599.1 - 0.086 11.9 0.2 0.093 11.8 0.1 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter zf-C2H2 PF00096.21 EKG17600.1 - 6.5e-08 32.4 6.5 1.2e-05 25.3 0.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG17600.1 - 4.5e-06 26.6 7.1 0.0011 19.1 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG17600.1 - 0.00012 22.1 13.0 0.0002 21.4 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EKG17600.1 - 0.018 14.8 0.3 0.046 13.6 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger PAT1 PF09770.4 EKG17600.1 - 4.9 5.2 27.7 0.93 7.6 16.9 1.3 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EF-hand_1 PF00036.27 EKG17603.1 - 5.2e-24 81.6 12.5 4.1e-08 31.9 0.1 4.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EKG17603.1 - 1.9e-23 80.1 3.8 5.8e-06 25.7 0.1 5.3 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 EKG17603.1 - 2.1e-21 75.8 4.5 1.8e-13 50.3 0.2 3.2 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EKG17603.1 - 2.3e-16 58.2 15.8 2.8e-05 23.2 0.0 4.9 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.1 EKG17603.1 - 5.7e-15 54.6 14.0 1.1e-05 24.9 0.8 4.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EKG17603.1 - 2.1e-08 33.8 7.0 0.0019 17.9 0.1 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EKG17603.1 - 0.00051 20.0 1.9 0.71 9.9 0.1 3.1 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EKG17603.1 - 0.0011 18.7 0.8 0.019 14.8 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EKG17603.1 - 0.0081 15.7 2.7 1.1 8.9 0.0 3.9 4 0 0 4 4 4 1 EF hand DUF1679 PF07914.6 EKG17603.1 - 0.013 14.1 0.6 0.77 8.3 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Toprim PF01751.17 EKG17603.1 - 0.015 15.3 0.0 2.1 8.3 0.0 2.3 1 1 0 2 2 2 0 Toprim domain EF-hand_2 PF09068.6 EKG17603.1 - 0.035 14.1 0.2 5 7.2 0.0 3.1 3 1 0 3 3 3 0 EF hand Mad3_BUB1_II PF08171.6 EKG17603.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 EMP70 PF02990.11 EKG17604.1 - 1.7e-197 657.0 2.8 2.2e-197 656.6 1.9 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Ribosomal_S28e PF01200.13 EKG17607.1 - 1e-32 111.6 2.9 1.1e-32 111.5 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e NIF3 PF01784.13 EKG17608.1 - 1.4e-61 208.1 0.0 1.8e-61 207.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EKG17609.1 - 4.4e-21 74.6 0.0 5.3e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein COG6 PF06419.6 EKG17610.1 - 2.7e-197 656.7 6.7 3e-197 656.5 4.7 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Laminin_I PF06008.9 EKG17610.1 - 0.0044 16.3 0.9 0.4 9.9 0.0 2.6 2 0 0 2 2 2 2 Laminin Domain I APG9 PF04109.11 EKG17611.1 - 1.2e-139 465.3 6.3 1.6e-139 464.9 4.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 ELFV_dehydrog PF00208.16 EKG17612.1 - 2.5e-59 200.7 0.0 8.5e-59 199.0 0.0 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EKG17612.1 - 3.4e-18 64.5 0.0 6.9e-13 46.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EKG17612.1 - 0.0059 16.1 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Aldedh PF00171.17 EKG17613.1 - 5.4e-11 41.4 5.2 6.5e-09 34.6 1.2 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Glyco_hydro_16 PF00722.16 EKG17614.1 - 5.4e-43 146.4 1.6 9.5e-43 145.6 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_20 PF00728.17 EKG17615.1 - 4.2e-87 292.5 0.0 7.1e-87 291.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EKG17615.1 - 5.6e-27 94.9 1.0 1.1e-26 93.9 0.7 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EKG17615.1 - 1e-10 42.2 0.2 4.4e-10 40.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 PHY PF00360.15 EKG17615.1 - 0.024 13.7 0.1 0.041 13.0 0.1 1.3 1 0 0 1 1 1 0 Phytochrome region p450 PF00067.17 EKG17616.1 - 9.3e-61 205.7 0.0 1.1e-60 205.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2889 PF11136.3 EKG17617.1 - 0.044 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2889) Macoilin PF09726.4 EKG17617.1 - 0.75 8.0 7.6 1 7.5 5.3 1.2 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 EKG17617.1 - 1.6 8.1 18.4 2.6 7.4 12.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_pol_Rpb2_6 PF00562.23 EKG17618.1 - 2.5e-73 247.0 0.1 3.2e-73 246.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_2 PF04561.9 EKG17618.1 - 7.8e-28 97.1 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EKG17618.1 - 7.5e-25 86.4 0.0 1.6e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EKG17618.1 - 9.1e-24 83.1 0.0 2e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.10 EKG17618.1 - 5.8e-14 51.5 0.0 8.6e-14 50.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_5 PF04567.12 EKG17618.1 - 4.4e-05 23.3 0.1 8.6e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF566 PF04484.7 EKG17619.1 - 0.38 10.2 3.8 0.44 10.0 2.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_S4 PF00163.14 EKG17620.1 - 2.1e-12 47.2 1.0 3.2e-12 46.6 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EKG17620.1 - 2.3e-11 42.9 0.0 4.4e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain RPA_interact_M PF14767.1 EKG17621.1 - 0.13 13.0 0.8 2.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Replication protein A interacting middle FA_desaturase PF00487.19 EKG17622.1 - 4.5e-37 127.8 30.6 6.2e-37 127.4 21.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase PGM_PMM_I PF02878.11 EKG17623.1 - 1.3e-37 128.4 0.0 2.4e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EKG17623.1 - 1.6e-24 86.2 0.2 3.6e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EKG17623.1 - 3.5e-10 39.9 0.0 6.5e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EKG17623.1 - 2.7e-07 30.4 0.0 1.1e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain tRNA-synt_1b PF00579.20 EKG17625.1 - 2.7e-64 217.1 0.0 3.4e-64 216.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) p450 PF00067.17 EKG17626.1 - 2.3e-48 164.8 0.0 3.9e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EKG17627.1 - 2.8e-08 33.5 12.8 5.1e-08 32.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.18 EKG17628.1 - 2.8e-19 70.0 0.0 4e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.14 EKG17628.1 - 0.056 13.8 3.7 0.1 12.9 2.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1011 PF06237.7 EKG17628.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1011) WD40 PF00400.27 EKG17629.1 - 2.3e-56 185.7 16.1 3.4e-11 42.5 0.0 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EKG17629.1 - 8e-08 30.8 0.2 0.0017 16.6 0.1 3.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EKG17629.1 - 3.2e-06 26.1 2.6 2.1 7.0 0.0 4.8 2 2 3 5 5 5 3 Nup133 N terminal like eIF2A PF08662.6 EKG17629.1 - 2.9e-05 23.8 0.0 0.0012 18.6 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EKG17629.1 - 0.0022 16.3 0.0 0.0029 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) VID27 PF08553.5 EKG17629.1 - 0.0023 16.2 0.1 0.17 10.0 0.0 2.7 1 1 2 3 3 3 2 VID27 cytoplasmic protein DUF1513 PF07433.6 EKG17629.1 - 0.0072 15.2 0.1 0.5 9.2 0.0 2.5 1 1 2 3 3 3 1 Protein of unknown function (DUF1513) DUF3445 PF11927.3 EKG17630.1 - 1.1e-78 264.0 0.0 1.5e-78 263.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 EKG17631.1 - 1.7e-86 290.8 13.2 2e-86 290.6 9.2 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.9 EKG17632.1 - 1.1e-48 164.5 1.8 4.6e-48 162.5 1.3 2.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region TFIIIC_sub6 PF10419.4 EKG17634.1 - 3.1e-13 48.9 0.0 5.6e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit CBM_5_12 PF02839.9 EKG17634.1 - 0.017 14.6 0.1 0.045 13.3 0.1 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain DUF946 PF06101.6 EKG17635.1 - 3.6e-10 38.4 2.1 5e-10 37.9 1.5 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Glyco_hydro_76 PF03663.9 EKG17637.1 - 5.7e-85 285.9 14.2 7.1e-85 285.6 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Proteasome PF00227.21 EKG17638.1 - 4.4e-49 166.3 0.1 5.3e-49 166.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Inp1 PF12634.2 EKG17639.1 - 2.3e-31 108.4 0.0 6.3e-31 107.0 0.0 1.8 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SNF2_N PF00176.18 EKG17640.1 - 7.4e-20 70.9 0.0 2.2e-18 66.1 0.0 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 EKG17640.1 - 2.6e-19 69.5 0.0 5.6e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 EKG17640.1 - 0.021 14.5 18.5 0.068 12.9 3.2 2.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG17640.1 - 0.026 14.5 14.5 0.061 13.3 1.6 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG17640.1 - 0.22 11.2 9.6 0.13 11.9 1.0 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG17640.1 - 0.7 9.7 18.0 0.084 12.7 4.1 2.9 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.1 EKG17640.1 - 1.2 8.7 14.1 6.1 6.5 3.3 2.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EKG17640.1 - 6.1 6.6 9.1 0.31 10.7 0.3 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Redoxin PF08534.5 EKG17641.1 - 7.4e-30 103.4 0.0 8.7e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EKG17641.1 - 8.3e-08 31.9 0.0 1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 EKG17642.1 - 5.3e-37 126.1 0.7 1.4e-36 124.7 0.5 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EKG17642.1 - 1.1e-21 76.9 0.1 2.4e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain W2 PF02020.13 EKG17643.1 - 1.1e-15 57.2 5.9 6.7e-15 54.8 3.8 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EKG17643.1 - 4e-11 41.8 15.5 0.0006 19.1 1.4 3.8 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EKG17643.1 - 2e-08 33.8 0.0 4.2e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EKG17643.1 - 4.5e-08 32.5 13.5 0.002 17.6 0.4 3.7 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EKG17643.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain IBR PF01485.16 EKG17644.1 - 4.9e-22 77.5 42.9 4e-11 42.6 4.0 4.6 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 EKG17644.1 - 1.6e-06 27.9 4.4 1.6e-06 27.9 3.1 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG17644.1 - 4.9e-05 22.8 38.9 0.00035 20.1 1.4 4.7 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG17644.1 - 0.00024 20.8 1.8 0.00024 20.8 1.3 3.6 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EKG17644.1 - 0.0061 16.2 4.1 0.0061 16.2 2.8 3.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EKG17644.1 - 0.039 13.6 0.9 0.039 13.6 0.6 3.7 3 0 0 3 3 3 0 RING-type zinc-finger UN_NPL4 PF11543.3 EKG17644.1 - 0.075 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DNA_ligase_ZBD PF03119.11 EKG17644.1 - 0.37 10.5 6.7 8.1 6.2 1.4 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C3HC4_4 PF15227.1 EKG17644.1 - 4.4 7.2 31.6 0.99 9.3 2.9 4.8 3 2 0 3 3 3 0 zinc finger of C3HC4-type, RING YcfA PF07927.7 EKG17645.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 YcfA-like protein Reo_sigmaC PF04582.7 EKG17646.1 - 1.4 7.9 12.6 0.39 9.8 6.1 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein OST3_OST6 PF04756.8 EKG17647.1 - 9e-23 80.5 2.7 1.3e-22 80.0 1.9 1.2 1 0 0 1 1 1 1 OST3 / OST6 family NADH-u_ox-rdase PF10785.4 EKG17647.1 - 0.047 13.9 2.9 3.1 8.1 0.1 3.2 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Ammonium_transp PF00909.16 EKG17650.1 - 2.5e-113 378.5 31.9 2.8e-113 378.3 22.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Clat_adaptor_s PF01217.15 EKG17651.1 - 3.2e-56 188.9 1.2 3.7e-56 188.7 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.2 EKG17652.1 - 3.2e-50 167.9 0.0 3e-32 110.3 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 EKG17652.1 - 1.4e-13 50.8 0.1 2.3e-12 46.9 0.0 2.6 2 1 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EKG17652.1 - 1.9e-12 46.9 0.1 7e-05 22.6 0.0 4.3 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.19 EKG17652.1 - 1.9e-11 43.9 0.0 1.8e-05 24.7 0.0 3.7 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EKG17652.1 - 9.7e-07 28.5 0.0 3.3e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.16 EKG17652.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EKG17652.1 - 0.032 12.6 0.2 0.061 11.7 0.0 1.4 2 0 0 2 2 2 0 Peptidase S46 Tricorn_PDZ PF14685.1 EKG17652.1 - 0.036 13.8 0.4 0.75 9.6 0.1 2.7 2 0 0 2 2 2 0 Tricorn protease PDZ domain DUF31 PF01732.11 EKG17652.1 - 0.14 11.4 0.2 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) SET PF00856.23 EKG17654.1 - 1.8e-08 34.8 0.0 2.4e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 SET domain Cuticle_3 PF11018.3 EKG17654.1 - 0.49 10.5 3.0 0.69 10.0 2.1 1.1 1 0 0 1 1 1 0 Pupal cuticle protein C1 Ppx-GppA PF02541.11 EKG17655.1 - 4.6e-06 26.0 0.0 8.6e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family F_bP_aldolase PF01116.15 EKG17655.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II LCAT PF02450.10 EKG17656.1 - 7.7e-97 324.7 0.1 9.2e-97 324.4 0.0 1.0 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.5 EKG17656.1 - 0.062 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Acetyltransf_1 PF00583.19 EKG17657.1 - 2e-17 62.9 0.0 3.1e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG17657.1 - 3.1e-10 40.0 0.0 4.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG17657.1 - 2.6e-09 36.6 0.0 4.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EKG17657.1 - 4.9e-09 36.4 0.0 5.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG17657.1 - 1.8e-08 34.5 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKG17657.1 - 3.9e-08 33.3 0.0 5.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG17657.1 - 7.1e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG17657.1 - 0.00027 20.7 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 EKG17657.1 - 0.12 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_4 PF13420.1 EKG17657.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cnd1 PF12717.2 EKG17658.1 - 1e-55 188.3 3.6 3.9e-51 173.4 0.5 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EKG17658.1 - 2.5e-27 95.5 0.1 2.5e-27 95.5 0.1 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EKG17658.1 - 1.7e-10 41.0 11.5 0.00043 20.4 0.0 6.2 5 3 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EKG17658.1 - 1.2e-06 28.0 15.0 0.058 13.5 0.0 8.3 10 0 0 10 10 10 2 HEAT repeat Adaptin_N PF01602.15 EKG17658.1 - 3.5e-05 22.3 6.1 0.39 8.9 0.1 4.0 3 1 1 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.1 EKG17658.1 - 7e-05 23.1 5.9 1.4 9.4 0.1 5.8 5 1 1 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 EKG17658.1 - 0.00039 20.2 0.0 0.34 10.8 0.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) YtzH PF14165.1 EKG17658.1 - 0.0046 17.1 0.0 0.026 14.7 0.0 2.3 1 0 0 1 1 1 1 YtzH-like protein Ald_Xan_dh_C2 PF02738.13 EKG17658.1 - 0.0071 14.7 0.0 0.012 13.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Cohesin_HEAT PF12765.2 EKG17658.1 - 0.091 12.7 0.4 64 3.6 0.0 4.4 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Pkinase PF00069.20 EKG17659.1 - 7.7e-44 149.7 0.0 9.6e-42 142.9 0.0 3.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17659.1 - 5e-14 51.9 0.0 8.2e-09 34.8 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 EKG17659.1 - 0.0013 18.5 0.3 0.18 11.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family AA_permease_2 PF13520.1 EKG17660.1 - 2.4e-55 187.7 47.0 3e-55 187.4 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG17660.1 - 1.5e-19 69.7 39.9 2e-19 69.2 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2721 PF11026.3 EKG17660.1 - 0.11 12.0 0.0 0.11 12.0 0.0 4.2 7 0 0 7 7 7 0 Protein of unknown function (DUF2721) VID27 PF08553.5 EKG17661.1 - 0 1138.3 0.1 0 1138.1 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein P53_C PF11619.3 EKG17661.1 - 0.013 15.1 0.1 0.053 13.2 0.1 2.1 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain PBP_sp32 PF07222.7 EKG17661.1 - 0.29 10.2 8.1 0.62 9.1 5.6 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDC45 PF02724.9 EKG17661.1 - 0.89 7.5 10.3 1.4 6.8 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EKG17661.1 - 1.9 6.2 17.1 3 5.6 11.8 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EKG17661.1 - 2.8 6.3 18.3 0.26 9.7 8.8 1.8 2 0 0 2 2 2 0 Daxx Family Ribosomal_S17 PF00366.15 EKG17662.1 - 0.048 13.7 1.3 0.082 12.9 0.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 Glyco_transf_20 PF00982.16 EKG17663.1 - 1.9e-200 666.3 0.0 2.2e-200 666.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EKG17663.1 - 0.0044 16.5 0.1 0.0093 15.4 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Cytochrom_B561 PF03188.11 EKG17665.1 - 3.7e-20 72.1 1.7 3.7e-20 72.1 1.2 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF3784 PF12650.2 EKG17665.1 - 0.02 14.8 0.5 0.02 14.8 0.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3784) Ferric_reduct PF01794.14 EKG17665.1 - 0.05 13.6 1.0 0.05 13.6 0.7 2.4 1 1 0 2 2 2 0 Ferric reductase like transmembrane component Cytochrom_B_N PF00033.14 EKG17665.1 - 0.14 11.4 10.8 0.061 12.6 1.5 2.7 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1980 PF09323.5 EKG17665.1 - 0.44 10.2 3.0 0.26 10.9 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) COX15-CtaA PF02628.10 EKG17665.1 - 2.5 6.8 15.9 13 4.5 11.0 2.1 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein DUF4149 PF13664.1 EKG17665.1 - 8.3 6.5 11.9 2.5 8.2 3.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) zf-C3HC4 PF00097.20 EKG17666.1 - 4.1e-05 23.1 1.8 7.4e-05 22.3 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG17666.1 - 0.00018 21.2 9.2 0.00018 21.2 6.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EKG17666.1 - 0.0066 16.3 1.9 0.017 15.0 1.3 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1839 PF08893.5 EKG17666.1 - 0.0081 15.1 0.0 0.05 12.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1839) zf-C3HC4_2 PF13923.1 EKG17666.1 - 0.027 14.5 4.8 0.055 13.4 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG17666.1 - 0.064 12.9 3.0 0.11 12.2 2.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG17666.1 - 0.26 11.0 5.5 0.5 10.1 3.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EKG17666.1 - 0.3 10.8 7.3 0.55 9.9 5.1 1.5 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 EKG17666.1 - 0.51 10.2 4.7 1.2 9.0 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EKG17666.1 - 1.8 8.7 7.1 4.2 7.5 4.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger ubiquitin PF00240.18 EKG17667.1 - 9.2e-25 85.8 0.0 1e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EKG17667.1 - 2.8e-17 62.1 0.0 3.1e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EKG17667.1 - 0.00034 20.8 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain CTDII PF01556.13 EKG17667.1 - 0.072 12.9 0.2 0.099 12.5 0.2 1.3 1 0 0 1 1 1 0 DnaJ C terminal domain Elongin_A PF06881.6 EKG17668.1 - 2.6e-27 95.3 1.4 2.6e-27 95.3 0.9 1.4 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4078 PF13300.1 EKG17668.1 - 0.017 15.2 0.9 0.039 14.0 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) DinB PF05163.7 EKG17668.1 - 0.027 14.2 0.1 0.054 13.1 0.1 1.6 1 0 0 1 1 1 0 DinB family THOC7 PF05615.8 EKG17669.1 - 6.1e-31 107.5 4.9 6.1e-31 107.5 3.4 1.7 1 1 0 1 1 1 1 Tho complex subunit 7 Slu7 PF11708.3 EKG17669.1 - 0.00081 19.2 6.7 0.00081 19.2 4.7 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor SPAM PF02090.10 EKG17669.1 - 0.076 13.0 12.1 0.12 12.3 8.4 1.3 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein AAA_13 PF13166.1 EKG17669.1 - 0.1 11.0 2.8 0.15 10.4 2.0 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EKG17669.1 - 0.28 10.0 5.3 0.37 9.6 3.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4600 PF15372.1 EKG17669.1 - 0.88 9.7 10.6 1.6 8.9 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) UPF0561 PF10573.4 EKG17669.1 - 6.6 6.5 12.7 1.2 8.9 1.4 2.8 2 1 1 3 3 3 0 Uncharacterised protein family UPF0561 CYSTM PF12734.2 EKG17670.1 - 0.048 13.7 70.9 0.1 12.6 23.6 5.5 2 2 0 2 2 2 0 Cysteine-rich TM module stress tolerance Exo5 PF09810.4 EKG17671.1 - 3.4e-118 394.5 0.1 4.1e-118 394.2 0.1 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Histone PF00125.19 EKG17672.1 - 1.2e-31 108.6 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EKG17672.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EKG17672.1 - 0.0035 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EKG17672.1 - 0.041 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EKG17673.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EKG17673.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EKG17673.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EKG17673.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EKG17673.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EKG17673.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1708 PF08101.6 EKG17675.1 - 3.8e-159 530.0 0.0 5.3e-159 529.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3140 PF11338.3 EKG17676.1 - 1.4e-31 108.4 1.2 1.7e-31 108.1 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) TMA7 PF09072.5 EKG17676.1 - 0.04 14.3 2.0 0.083 13.3 1.4 1.6 1 1 0 1 1 1 0 Translation machinery associated TMA7 GatB_Yqey PF02637.13 EKG17676.1 - 0.31 10.7 2.2 0.41 10.3 0.6 1.6 2 0 0 2 2 2 0 GatB domain SRF-TF PF00319.13 EKG17677.1 - 4e-24 83.6 0.1 6e-24 83.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) EF-hand_1 PF00036.27 EKG17678.1 - 1.6e-29 98.9 2.6 8.8e-08 30.9 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EKG17678.1 - 3e-25 87.5 5.8 1.4e-08 34.1 0.2 5.1 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.1 EKG17678.1 - 1.3e-23 80.6 4.9 4.9e-05 22.8 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 EKG17678.1 - 5.9e-23 80.7 5.1 4.7e-09 36.2 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EKG17678.1 - 6.2e-20 69.5 4.5 8.9e-05 21.6 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.2 EKG17678.1 - 0.053 13.2 0.2 0.38 10.5 0.1 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand PCNA_N PF00705.13 EKG17680.1 - 9.1e-54 180.3 4.2 9.1e-54 180.3 2.9 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EKG17680.1 - 1.4e-52 176.9 0.1 8.6e-52 174.4 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EKG17680.1 - 8.8e-10 38.1 0.7 1.6e-09 37.2 0.5 1.5 1 0 0 1 1 1 1 Rad9 Phos_pyr_kin PF08543.7 EKG17680.1 - 1.1e-09 37.9 0.0 3.8e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Rad1 PF02144.11 EKG17680.1 - 2.6e-07 29.6 2.0 9.2e-05 21.3 0.1 2.2 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 PfkB PF00294.19 EKG17680.1 - 1.1e-05 24.7 0.7 2.6e-05 23.5 0.0 2.0 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Hus1 PF04005.7 EKG17680.1 - 0.0016 17.4 1.4 0.013 14.4 0.2 2.5 2 1 0 2 2 2 1 Hus1-like protein IL12p40_C PF10420.4 EKG17680.1 - 0.88 9.7 2.8 15 5.7 0.1 2.9 4 0 0 4 4 4 0 Cytokine interleukin-12p40 C-terminus dUTPase PF00692.14 EKG17681.1 - 1.2e-38 131.5 0.0 1.6e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase SWI-SNF_Ssr4 PF08549.5 EKG17681.1 - 0.027 12.8 2.3 0.032 12.5 1.6 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ECH PF00378.15 EKG17681.1 - 0.08 12.0 0.1 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family NPV_P10 PF05531.7 EKG17682.1 - 1.4e-05 25.2 4.9 0.012 15.7 0.8 2.8 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 EKG17682.1 - 0.00037 20.5 10.4 0.004 17.2 1.3 3.6 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkip-1 PF06878.6 EKG17682.1 - 0.00042 20.2 0.5 0.00042 20.2 0.4 2.5 2 1 1 3 3 3 1 Pkip-1 protein TPR_MLP1_2 PF07926.7 EKG17682.1 - 0.0048 16.6 7.6 0.0048 16.6 5.3 3.9 4 1 0 4 4 4 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EKG17682.1 - 0.056 12.6 12.0 1.3 8.1 0.1 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Zn_ribbon_2 PF12674.2 EKG17682.1 - 0.058 13.7 0.1 25 5.3 0.0 3.0 2 0 0 2 2 2 0 Putative zinc ribbon domain Prominin PF05478.6 EKG17682.1 - 0.34 8.4 2.4 0.48 7.8 1.7 1.3 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.1 EKG17682.1 - 0.37 9.1 18.1 0.066 11.6 6.1 2.1 1 1 1 2 2 2 0 AAA domain Mod_r PF07200.8 EKG17682.1 - 0.39 10.6 20.5 0.036 13.9 3.2 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein LOH1CR12 PF10158.4 EKG17682.1 - 0.39 10.5 3.8 4.5 7.0 0.3 3.1 2 1 1 3 3 3 0 Tumour suppressor protein zf-CCHC_4 PF14392.1 EKG17682.1 - 1.4 8.6 4.5 7.9 6.2 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle Laminin_II PF06009.7 EKG17682.1 - 1.5 8.5 17.8 0.025 14.3 2.3 3.8 2 1 1 4 4 4 0 Laminin Domain II EMP24_GP25L PF01105.19 EKG17682.1 - 2.7 7.6 5.2 0.97 9.1 0.8 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Cauli_AT PF03233.8 EKG17682.1 - 6.3 6.4 8.8 0.4 10.3 0.5 2.8 3 0 0 3 3 3 0 Aphid transmission protein YqjK PF13997.1 EKG17682.1 - 7.4 6.8 6.5 6.7 6.9 0.4 3.0 3 0 0 3 3 3 0 YqjK-like protein DUF16 PF01519.11 EKG17682.1 - 8.3 6.6 10.7 4.8 7.4 2.5 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Methyltransf_11 PF08241.7 EKG17684.1 - 3.5e-05 24.2 0.0 0.00011 22.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG17684.1 - 0.016 14.8 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ribul_P_3_epim PF00834.14 EKG17685.1 - 6.8e-49 165.7 0.0 8e-48 162.2 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family Amidohydro_2 PF04909.9 EKG17685.1 - 0.02 14.4 0.0 0.046 13.2 0.0 1.5 1 1 0 1 1 1 0 Amidohydrolase QRPTase_C PF01729.14 EKG17685.1 - 0.031 13.7 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain ELMO_CED12 PF04727.8 EKG17686.1 - 2.9e-47 160.3 0.2 4.6e-47 159.7 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3552 PF12072.3 EKG17686.1 - 0.016 14.3 1.9 0.031 13.4 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1752 PF08550.5 EKG17687.1 - 1.2e-08 34.3 5.3 2.6e-08 33.3 3.7 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) LSM PF01423.17 EKG17689.1 - 8.6e-16 57.2 0.6 1.2e-15 56.7 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKG17689.1 - 0.0082 16.0 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EKG17689.1 - 0.012 15.3 0.1 0.028 14.1 0.0 1.7 1 1 1 2 2 2 0 Gem-associated protein 7 (Gemin7) Phosphodiest PF01663.17 EKG17690.1 - 2.2e-89 300.3 1.0 2.2e-89 300.3 0.7 1.4 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EKG17690.1 - 0.0003 20.0 0.9 0.021 14.0 0.0 2.9 2 1 1 3 3 3 1 Sulfatase Ribosomal_S19e PF01090.14 EKG17690.1 - 0.11 11.9 0.6 0.21 10.9 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S19e DUF3446 PF11928.3 EKG17690.1 - 0.39 10.9 6.3 0.87 9.8 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) eIF-3_zeta PF05091.7 EKG17692.1 - 8.6e-194 644.9 0.0 9.7e-194 644.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) adh_short_C2 PF13561.1 EKG17693.1 - 7.5e-17 61.9 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG17693.1 - 3.3e-16 59.6 0.0 8.3e-16 58.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG17693.1 - 2.5e-06 27.2 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 KR domain HLH PF00010.21 EKG17695.1 - 2.1e-16 59.3 0.2 4.8e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 EKG17695.1 - 0.0076 16.5 3.1 0.022 15.0 2.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Dynamitin PF04912.9 EKG17695.1 - 0.018 13.8 0.4 0.024 13.4 0.3 1.2 1 0 0 1 1 1 0 Dynamitin DUF4570 PF15134.1 EKG17695.1 - 0.037 13.8 2.8 0.11 12.4 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF4164 PF13747.1 EKG17695.1 - 0.043 13.9 3.3 0.087 12.9 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) HALZ PF02183.13 EKG17695.1 - 0.08 12.6 2.5 0.74 9.5 0.0 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 EKG17695.1 - 0.9 9.5 5.8 0.82 9.6 1.1 2.5 2 1 1 3 3 3 0 bZIP transcription factor dCMP_cyt_deam_1 PF00383.17 EKG17697.1 - 1.3e-09 37.6 0.1 4e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EKG17697.1 - 0.00053 19.4 0.9 0.037 13.3 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Ank_2 PF12796.2 EKG17698.1 - 6.2e-35 119.4 2.5 2.7e-15 56.4 0.5 4.4 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EKG17698.1 - 9.8e-31 104.0 10.9 3.3e-06 26.6 0.1 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EKG17698.1 - 7.4e-23 80.0 8.2 1.6e-05 24.9 0.0 5.7 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG17698.1 - 1.5e-22 77.4 5.4 3.3e-06 26.8 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EKG17698.1 - 5.6e-22 77.6 3.9 2.7e-06 27.7 0.0 5.2 4 2 1 5 5 5 5 Ankyrin repeats (many copies) Aldo_ket_red PF00248.16 EKG17699.1 - 5.7e-66 222.2 0.0 6.4e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.1 EKG17700.1 - 1.5e-19 70.6 0.0 3e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG17700.1 - 1.8e-11 44.1 0.1 3.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 EKG17701.1 - 1.1e-07 32.1 0.2 1.9e-07 31.3 0.1 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EKG17701.1 - 0.00058 18.4 0.1 0.65 8.4 0.0 2.5 2 1 1 3 3 3 3 Protein of unknown function (DUF1479) Peptidase_S15 PF02129.13 EKG17702.1 - 1.1e-37 129.9 0.0 1.8e-36 126.0 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EKG17702.1 - 1.3e-27 97.0 0.0 1.8e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EKG17702.1 - 0.00029 20.8 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 EKG17705.1 - 8.7e-10 37.9 0.1 1.6e-09 37.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_FMN PF00724.15 EKG17706.1 - 5.5e-52 176.8 0.0 6.2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EKG17706.1 - 0.0025 17.1 0.0 0.19 10.9 0.0 2.2 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel EthD PF07110.6 EKG17707.1 - 1.3e-12 48.4 1.4 2.7e-12 47.4 0.3 1.9 2 0 0 2 2 2 1 EthD domain HET PF06985.6 EKG17708.1 - 5.1e-32 110.9 0.2 1e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.8 EKG17710.1 - 8.3e-07 28.7 2.8 1.3e-05 24.8 0.2 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG17710.1 - 0.00036 20.3 1.8 0.00073 19.3 1.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG17710.1 - 0.0015 18.1 0.1 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tim44 PF04280.10 EKG17712.1 - 2.5e-32 111.8 0.1 1.3e-31 109.5 0.0 2.1 2 0 0 2 2 2 1 Tim44-like domain FancD2 PF14631.1 EKG17712.1 - 3.3 4.6 5.3 5.1 4.0 3.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Ribosomal_S11 PF00411.14 EKG17713.1 - 8.6e-13 48.4 0.3 1.1e-12 48.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Peptidase_C97 PF05903.9 EKG17714.1 - 1.6e-30 105.9 0.0 2.2e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EKG17714.1 - 0.0012 18.8 0.1 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase SURF2 PF05477.6 EKG17714.1 - 0.34 10.0 3.9 0.55 9.3 2.7 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) YchF-GTPase_C PF06071.8 EKG17715.1 - 1.9e-33 114.1 0.3 4.5e-33 112.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EKG17715.1 - 5.1e-12 45.7 0.0 1.2e-11 44.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG17715.1 - 0.00034 19.9 0.0 0.00079 18.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EKG17715.1 - 0.0017 18.1 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain SecA_PP_bind PF01043.15 EKG17715.1 - 0.05 13.9 0.2 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 SecA preprotein cross-linking domain AAA_14 PF13173.1 EKG17715.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EKG17715.1 - 0.075 12.8 0.1 2.1 8.1 0.0 2.7 2 1 0 3 3 3 0 Dynamin family MobB PF03205.9 EKG17715.1 - 0.087 12.5 0.5 3.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EKG17715.1 - 0.36 11.1 2.2 2 8.7 1.6 2.1 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EKG17717.1 - 3.5e-34 118.0 27.4 5e-34 117.5 19.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SGL PF08450.7 EKG17718.1 - 3.1e-08 33.3 0.0 6.2e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EKG17718.1 - 0.00029 20.6 2.3 0.04 13.9 0.0 3.1 3 0 0 3 3 3 2 NHL repeat p450 PF00067.17 EKG17719.1 - 1.1e-72 245.0 0.0 1.5e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ANTH PF07651.11 EKG17719.1 - 0.043 12.5 0.1 0.07 11.8 0.1 1.3 1 0 0 1 1 1 0 ANTH domain CTDII PF01556.13 EKG17720.1 - 2.8e-12 46.3 0.0 2.8e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKG17720.1 - 4.2e-07 29.9 3.4 6.3e-07 29.3 2.3 1.3 1 0 0 1 1 1 1 DnaJ central domain MFS_1 PF07690.11 EKG17721.1 - 4.4e-35 121.0 21.6 4.4e-35 121.0 15.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.16 EKG17722.1 - 2.8e-55 187.6 12.5 3.5e-55 187.2 8.7 1.1 1 0 0 1 1 1 1 POT family adh_short PF00106.20 EKG17723.1 - 7.3e-14 52.0 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG17723.1 - 0.0019 17.8 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG17723.1 - 0.021 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EKG17723.1 - 0.037 13.8 1.4 0.73 9.6 0.1 2.9 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EI24 PF07264.6 EKG17724.1 - 0.0001 21.8 16.0 0.0003 20.2 11.1 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF2839 PF10999.3 EKG17724.1 - 0.11 12.5 0.1 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Pex24p PF06398.6 EKG17724.1 - 6.1 5.5 11.3 0.029 13.1 1.7 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin MFS_1 PF07690.11 EKG17725.1 - 8e-26 90.5 62.6 7.8e-25 87.3 33.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp PF00026.18 EKG17726.1 - 2.1e-108 362.3 0.2 2.5e-108 362.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKG17726.1 - 4.5e-13 49.4 0.1 1.9e-12 47.4 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EKG17726.1 - 5.7e-07 29.9 0.1 0.0052 17.2 0.0 3.3 2 1 1 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EKG17726.1 - 1.5e-05 24.6 0.0 0.00014 21.4 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.13 EKG17726.1 - 0.11 12.6 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain gag-asp_proteas PF13975.1 EKG17726.1 - 0.14 12.0 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SNF5 PF04855.7 EKG17727.1 - 7.6e-75 251.5 0.5 1.4e-74 250.6 0.3 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GPP34 PF05719.6 EKG17728.1 - 3.7e-67 226.3 0.2 4.8e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 EKG17729.1 - 3e-12 46.6 0.3 4e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EKG17729.1 - 1.5e-06 28.1 0.2 2e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EKG17729.1 - 0.027 14.5 0.3 0.037 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Fer4 PF00037.22 EKG17730.1 - 8.3e-14 50.5 16.0 5e-08 32.2 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EKG17730.1 - 3.4e-12 46.5 10.5 5.2e-12 45.9 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EKG17730.1 - 5e-10 39.0 4.3 5.5e-05 22.9 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EKG17730.1 - 1.6e-09 37.4 22.2 5.6e-08 32.4 8.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EKG17730.1 - 2e-09 38.0 7.3 0.00019 22.1 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 EKG17730.1 - 2.6e-09 37.1 11.0 4.8e-09 36.3 7.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EKG17730.1 - 7e-08 32.3 20.3 1.5e-05 24.9 7.9 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EKG17730.1 - 7.8e-08 31.8 14.2 0.00041 20.0 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EKG17730.1 - 2.3e-07 30.3 17.1 0.0012 18.6 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EKG17730.1 - 4.8e-06 26.4 12.7 0.00055 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EKG17730.1 - 6.5e-06 26.4 9.6 0.00057 20.1 7.6 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EKG17730.1 - 5.2e-05 23.5 10.0 0.018 15.4 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EKG17730.1 - 0.0076 16.6 15.2 0.28 11.5 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EKG17730.1 - 0.018 15.6 13.3 0.27 11.8 1.2 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EKG17730.1 - 0.063 13.8 16.9 0.15 12.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EKG17730.1 - 0.2 11.8 4.6 0.25 11.4 0.1 2.1 1 1 1 2 2 2 0 c-SKI Smad4 binding domain SURF6 PF04935.7 EKG17731.1 - 5.6e-49 166.3 50.9 5.6e-49 166.3 35.3 4.2 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EKG17731.1 - 5.5e-20 71.1 4.3 5.5e-20 71.1 3.0 8.3 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 CAF-1_p150 PF11600.3 EKG17731.1 - 0.0061 15.9 21.2 0.0061 15.9 14.7 4.0 2 1 0 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Homeobox PF00046.24 EKG17734.1 - 1.1e-08 34.5 0.1 2.1e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EKG17734.1 - 1.1e-07 31.3 0.0 1.1e-07 31.3 0.0 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 EKG17734.1 - 0.00068 18.6 0.1 0.0038 16.2 0.0 2.3 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez MBOAT PF03062.14 EKG17735.1 - 2e-38 132.2 16.9 2e-38 132.2 11.7 2.5 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EKG17735.1 - 7.1e-05 22.8 3.9 0.0002 21.3 2.7 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family UDP-g_GGTase PF06427.6 EKG17737.1 - 1e-66 224.2 0.0 1.8e-66 223.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EKG17737.1 - 0.0001 21.7 1.7 0.00023 20.6 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 Drc1-Sld2 PF11719.3 EKG17738.1 - 3.8e-58 197.5 34.3 4.9e-58 197.2 23.8 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Amidase PF01425.16 EKG17739.1 - 2.2e-90 303.6 0.0 3.4e-90 303.0 0.0 1.3 1 0 0 1 1 1 1 Amidase Takusan PF04822.8 EKG17740.1 - 0.0014 18.3 1.3 0.0014 18.3 0.9 2.5 3 0 0 3 3 3 1 Takusan Protocadherin PF08374.6 EKG17740.1 - 0.023 14.3 0.3 0.023 14.3 0.2 4.0 3 3 2 5 5 5 0 Protocadherin Reo_sigmaC PF04582.7 EKG17740.1 - 0.17 11.0 2.6 2.3 7.3 0.3 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein MAD PF05557.8 EKG17742.1 - 1e-60 205.7 68.6 1.4e-60 205.3 47.5 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein Baculo_PEP_C PF04513.7 EKG17742.1 - 0.011 15.5 5.2 0.011 15.5 3.6 3.7 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3166 PF11365.3 EKG17742.1 - 0.012 16.0 4.0 0.012 16.0 2.8 5.8 3 3 5 8 8 8 0 Protein of unknown function (DUF3166) GAS PF13851.1 EKG17742.1 - 0.28 10.3 82.9 0.19 10.8 7.6 5.4 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EKG17742.1 - 4 6.5 24.3 1.4 8.0 2.3 4.6 2 2 3 5 5 5 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EKG17742.1 - 6.5 6.2 67.9 0.023 14.2 3.1 6.9 1 1 4 6 6 6 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DIL PF01843.14 EKG17743.1 - 6.8e-20 70.9 0.7 2.5e-12 46.5 0.1 2.4 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 EKG17743.1 - 8.4e-20 70.9 0.1 8.9e-19 67.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKG17743.1 - 1.2e-16 59.6 0.1 1.5e-06 27.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EKG17743.1 - 1.2e-11 43.6 0.2 0.00091 19.2 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EKG17743.1 - 2.4e-11 43.8 0.5 8.1e-07 29.3 0.0 4.1 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG17743.1 - 6.5e-11 42.1 0.1 6.2e-07 29.4 0.0 3.7 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Mnd1 PF03962.10 EKG17743.1 - 2.3 7.8 5.1 2.7 7.6 0.1 3.1 3 1 0 4 4 4 0 Mnd1 family HATPase_c PF02518.21 EKG17744.1 - 2.6e-29 101.1 0.1 6.9e-29 99.8 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG17744.1 - 7.8e-22 77.4 0.6 5.3e-19 68.2 0.1 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EKG17744.1 - 4.3e-20 71.4 0.2 3.1e-19 68.7 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EKG17744.1 - 9.2e-17 61.6 2.0 7.9e-16 58.5 0.0 3.3 4 0 0 4 4 4 1 AAA ATPase domain Pkinase PF00069.20 EKG17744.1 - 2.8e-09 36.5 0.0 6.6e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain GAF_2 PF13185.1 EKG17744.1 - 1.7e-07 31.8 0.1 4.6e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EKG17744.1 - 1.3e-06 28.5 0.1 2.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain NACHT PF05729.7 EKG17744.1 - 0.00071 19.2 0.0 0.0052 16.4 0.0 2.6 1 1 0 1 1 1 1 NACHT domain Pkinase_Tyr PF07714.12 EKG17744.1 - 0.0024 16.9 0.0 0.0049 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_22 PF13401.1 EKG17744.1 - 0.0051 16.9 0.4 0.68 10.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 EKG17745.1 - 1.1e-38 133.3 3.3 1.3e-38 133.1 2.3 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG17745.1 - 6.9e-24 84.2 2.8 2.4e-23 82.4 2.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG17745.1 - 2e-19 70.0 0.0 5.1e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EKG17745.1 - 1.7e-08 34.2 0.0 2.9e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EKG17745.1 - 6.5e-07 29.7 0.1 8.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EKG17745.1 - 5.2e-05 22.9 0.7 6.5e-05 22.5 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKG17745.1 - 8.5e-05 22.0 0.6 0.67 9.3 0.0 2.9 2 1 0 3 3 3 2 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EKG17745.1 - 9e-05 22.1 2.4 0.0041 16.7 0.3 2.2 1 1 1 2 2 2 1 Serine hydrolase Ndr PF03096.9 EKG17745.1 - 0.00049 18.6 0.0 0.002 16.6 0.0 1.8 1 1 0 1 1 1 1 Ndr family PGAP1 PF07819.8 EKG17745.1 - 0.0037 16.8 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.6 EKG17745.1 - 0.034 13.8 0.0 0.08 12.6 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 EKG17745.1 - 0.051 12.4 0.8 0.12 11.1 0.6 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.13 EKG17745.1 - 0.097 11.9 0.0 9.6 5.4 0.0 2.8 2 2 0 2 2 2 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 EKG17745.1 - 0.1 10.9 0.9 2.5 6.3 0.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 EKG17745.1 - 0.11 11.9 1.4 0.2 11.0 1.0 1.5 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EKG17745.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) FRQ PF09421.5 EKG17747.1 - 2.8e-132 442.5 50.7 1.8e-131 439.8 35.2 1.9 1 1 0 1 1 1 1 Frequency clock protein Leu_zip PF15294.1 EKG17747.1 - 0.00075 18.6 1.1 0.0015 17.6 0.7 1.4 1 0 0 1 1 1 1 Leucine zipper Herpes_BLRF2 PF05812.7 EKG17747.1 - 0.029 14.1 0.4 0.029 14.1 0.3 2.3 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein ODC_AZ PF02100.12 EKG17748.1 - 3e-22 78.1 0.0 3.5e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme OB_NTP_bind PF07717.11 EKG17749.1 - 1.1e-24 86.4 0.0 3e-24 85.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKG17749.1 - 1.5e-22 79.4 0.0 1.5e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKG17749.1 - 2.1e-13 49.9 0.0 5.3e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG17749.1 - 4.2e-06 26.3 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKG17749.1 - 0.00015 21.9 0.0 0.00045 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EKG17749.1 - 0.024 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EKG17749.1 - 0.034 13.8 0.0 0.082 12.6 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain Pil1 PF13805.1 EKG17750.1 - 1.4e-95 319.5 2.6 1.4e-95 319.5 1.8 1.4 2 0 0 2 2 2 1 Eisosome component PIL1 FAM92 PF06730.6 EKG17750.1 - 0.04 13.2 1.9 0.058 12.7 1.3 1.3 1 0 0 1 1 1 0 FAM92 protein DUF1018 PF06252.7 EKG17750.1 - 0.32 11.5 3.8 0.29 11.6 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) APG6 PF04111.7 EKG17750.1 - 1.8 7.5 9.0 0.29 10.1 3.8 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 TSA PF03249.8 EKG17751.1 - 0.13 10.7 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 Type specific antigen GSG-1 PF07803.6 EKG17752.1 - 0.46 10.0 7.5 0.76 9.3 0.5 2.5 2 0 0 2 2 2 0 GSG1-like protein Chon_Sulph_att PF06566.6 EKG17752.1 - 3.5 7.1 10.3 0.75 9.3 1.9 2.3 2 1 0 2 2 2 0 Chondroitin sulphate attachment domain Cupin_1 PF00190.17 EKG17753.1 - 1e-09 37.9 0.0 1.3e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EKG17753.1 - 2.5e-06 26.8 0.0 3.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 EKG17753.1 - 0.03 13.9 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase CDO_I PF05995.7 EKG17753.1 - 0.16 11.1 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Cysteine dioxygenase type I E1-E2_ATPase PF00122.15 EKG17754.1 - 6.7e-79 264.1 0.1 1.2e-78 263.2 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG17754.1 - 1.6e-44 151.6 0.4 1.6e-44 151.6 0.3 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG17754.1 - 3e-29 102.9 0.0 3.3e-28 99.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG17754.1 - 1.6e-13 51.3 0.0 3.9e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG17754.1 - 1.7e-13 50.3 0.0 3.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKG17754.1 - 8.2e-05 22.2 1.5 0.00026 20.6 0.7 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EKG17755.1 - 9.4e-41 138.2 0.0 2.1e-40 137.1 0.0 1.6 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EKG17755.1 - 8e-09 34.5 0.1 1.7e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EKG17755.1 - 3 7.3 5.0 1.6 8.2 0.0 2.5 3 0 0 3 3 3 0 ScpA/B protein RNase_P_p30 PF01876.11 EKG17757.1 - 0.00021 20.5 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Ribosomal_L27e PF01777.13 EKG17758.1 - 6.7e-38 128.6 5.0 8.7e-38 128.3 3.5 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EKG17758.1 - 0.0011 18.6 0.7 0.0026 17.4 0.1 2.1 2 0 0 2 2 2 1 KOW motif F-box-like PF12937.2 EKG17760.1 - 0.0027 17.3 0.1 0.052 13.2 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKG17760.1 - 0.043 13.4 0.0 0.043 13.4 0.0 3.9 5 0 0 5 5 5 0 F-box domain adh_short PF00106.20 EKG17761.1 - 3e-21 76.0 0.9 6.6e-21 74.9 0.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG17761.1 - 1.8e-17 63.9 0.0 2.5e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG17761.1 - 1.6e-05 24.6 0.2 8e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG17761.1 - 0.00078 18.9 0.1 0.024 14.1 0.0 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG17761.1 - 0.002 18.1 4.4 0.28 11.1 3.1 2.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG17761.1 - 0.039 13.2 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EKG17761.1 - 0.045 12.6 0.1 0.23 10.2 0.1 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain RabGAP-TBC PF00566.13 EKG17763.1 - 1.3e-35 122.8 0.0 2e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Coatomer_WDAD PF04053.9 EKG17766.1 - 1.4e-151 505.2 0.0 2.6e-151 504.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EKG17766.1 - 2.4e-81 273.4 0.1 3.3e-81 273.0 0.1 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EKG17766.1 - 7.6e-49 161.9 13.7 1.5e-08 34.2 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EKG17766.1 - 0.029 12.5 6.4 0.54 8.3 0.0 3.5 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.15 EKG17766.1 - 0.061 12.9 0.2 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Region in Clathrin and VPS TrbC_Ftype PF09673.5 EKG17766.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Cupin_1 PF00190.17 EKG17768.1 - 1.8e-07 30.7 0.0 3.6e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Cupin AOX PF01786.12 EKG17769.1 - 2e-93 311.5 0.3 2.4e-93 311.2 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase SSXT PF05030.7 EKG17770.1 - 0.061 12.9 0.3 14 5.3 0.1 2.3 2 0 0 2 2 2 0 SSXT protein (N-terminal region) SRP14 PF02290.10 EKG17771.1 - 9.8e-24 83.1 0.8 1.7e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein GHBP PF12772.2 EKG17771.1 - 0.035 13.5 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding MIF4G PF02854.14 EKG17772.1 - 3e-23 82.3 4.1 5.8e-23 81.4 2.8 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EKG17772.1 - 4e-18 65.1 0.0 9.6e-18 63.9 0.0 1.7 1 0 0 1 1 1 1 MA3 domain Pyr_redox_dim PF02852.17 EKG17773.1 - 7.8e-40 135.3 0.8 2.6e-39 133.6 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EKG17773.1 - 2e-39 135.5 16.2 9.5e-37 126.8 11.2 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG17773.1 - 4e-22 78.4 14.0 9.8e-21 73.9 1.9 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG17773.1 - 2.1e-10 40.4 6.9 7.8e-06 25.8 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EKG17773.1 - 7.2e-10 38.5 0.3 7.2e-10 38.5 0.2 3.1 3 1 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG17773.1 - 4.1e-09 36.7 1.6 3.5e-05 23.9 0.4 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG17773.1 - 2.7e-07 29.7 16.9 4.4e-06 25.8 4.8 3.2 2 2 1 3 3 3 2 Glucose inhibited division protein A DAO PF01266.19 EKG17773.1 - 3e-07 29.6 26.2 0.0014 17.5 4.2 4.0 2 2 2 4 4 4 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG17773.1 - 5.2e-07 28.8 15.9 5.8e-07 28.6 3.1 2.8 3 1 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 EKG17773.1 - 1.2e-06 27.2 17.3 0.00021 19.8 1.7 4.1 4 0 0 4 4 4 3 HI0933-like protein K_oxygenase PF13434.1 EKG17773.1 - 3.7e-06 26.1 0.3 0.04 12.8 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 EKG17773.1 - 4.1e-06 26.4 4.6 0.0014 18.2 0.2 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EKG17773.1 - 7.8e-06 25.1 6.3 4.9e-05 22.5 0.1 2.4 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EKG17773.1 - 0.00017 20.8 12.9 0.17 10.8 1.5 3.3 3 0 0 3 3 3 3 FAD binding domain Lycopene_cycl PF05834.7 EKG17773.1 - 0.00086 18.3 3.4 0.0087 15.0 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EKG17773.1 - 0.039 13.1 1.2 4.3 6.4 0.3 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EKG17773.1 - 0.049 13.8 5.2 0.18 12.0 0.2 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 EKG17773.1 - 0.21 10.6 0.4 0.56 9.2 0.2 1.6 1 1 1 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EKG17773.1 - 0.47 9.0 8.6 0.23 10.0 0.8 2.4 2 0 0 2 2 2 0 Tryptophan halogenase THF_DHG_CYH_C PF02882.14 EKG17773.1 - 1.2 8.1 7.7 1 8.4 0.2 3.9 5 1 0 5 5 5 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EKG17773.1 - 2.6 7.6 13.5 0.076 12.6 1.3 2.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4200 PF13863.1 EKG17775.1 - 0.011 15.6 0.1 0.011 15.6 0.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) TTKRSYEDQ PF10212.4 EKG17775.1 - 1.5 7.6 16.9 0.12 11.2 8.5 1.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF3919 PF13057.1 EKG17775.1 - 3 7.2 7.1 6 6.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3919) Tweety PF04906.8 EKG17775.1 - 4.1 5.7 3.6 6 5.1 2.5 1.1 1 0 0 1 1 1 0 Tweety Retrotrans_gag PF03732.12 EKG17775.1 - 4.3 7.4 7.3 22 5.1 0.6 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein IncA PF04156.9 EKG17775.1 - 7.6 6.0 37.4 0.039 13.5 15.8 3.0 3 0 0 3 3 3 0 IncA protein Ribosomal_L7Ae PF01248.21 EKG17776.1 - 2e-26 91.3 0.0 2.3e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L16 PF00252.13 EKG17777.1 - 2.7e-32 111.2 0.1 3.5e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RCR PF12273.3 EKG17778.1 - 7.2e-15 55.6 29.7 2e-14 54.2 20.6 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EKG17778.1 - 0.00033 20.3 5.0 0.00042 20.0 0.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) OSTbeta PF15048.1 EKG17778.1 - 0.041 13.9 0.1 0.058 13.4 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Rhabdo_glycop PF00974.13 EKG17778.1 - 0.045 12.0 0.9 0.06 11.5 0.6 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein GP41 PF00517.12 EKG17778.1 - 0.054 13.0 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein Amino_oxidase PF01593.19 EKG17779.1 - 2.6e-23 82.8 0.3 3.3e-22 79.1 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKG17779.1 - 5.1e-12 45.6 0.2 1.3e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG17779.1 - 2e-09 36.8 0.9 5.1e-07 28.9 0.1 2.8 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG17779.1 - 9.1e-06 25.9 0.4 0.053 13.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG17779.1 - 0.0046 16.7 0.3 0.056 13.2 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG17779.1 - 0.0091 16.0 0.1 2.1 8.3 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG17779.1 - 0.018 14.9 0.2 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG17779.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EKG17779.1 - 0.03 13.2 0.0 5.3 5.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EKG17779.1 - 0.069 11.7 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EKG17779.1 - 0.083 11.3 0.3 3.5 5.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein zf-CCCH_2 PF14608.1 EKG17780.1 - 7.7e-07 28.8 59.9 0.0014 18.5 3.4 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EKG17780.1 - 0.00038 20.5 0.0 0.00073 19.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-tcix PF14952.1 EKG17780.1 - 0.99 8.7 19.6 5.7 6.3 0.2 4.4 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding RRM_1 PF00076.17 EKG17781.1 - 1.7e-11 43.6 0.0 2.3e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG17781.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG17781.1 - 2.4e-07 30.4 0.0 3.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKG17781.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Band_7 PF01145.20 EKG17782.1 - 1.5e-23 83.6 2.1 2.3e-23 83.0 1.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family WD40 PF00400.27 EKG17782.1 - 0.00018 21.2 2.8 1.6 8.7 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Methyltransf_26 PF13659.1 EKG17784.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EKG17785.1 - 1.4e-39 135.8 0.0 3e-39 134.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17785.1 - 5.2e-24 84.7 0.0 8.7e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG17785.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Vac7 PF12751.2 EKG17786.1 - 9.3e-139 462.5 1.5 9.3e-139 462.5 1.1 1.9 1 1 1 2 2 2 1 Vacuolar segregation subunit 7 TFIID-18kDa PF02269.11 EKG17788.1 - 3.2e-28 97.3 0.7 2.6e-27 94.4 0.4 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit DUF953 PF06110.6 EKG17788.1 - 0.042 13.2 0.0 0.082 12.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) CBFD_NFYB_HMF PF00808.18 EKG17788.1 - 0.12 12.5 0.1 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TP_methylase PF00590.15 EKG17789.1 - 2.1e-19 70.0 0.1 4.2e-19 69.0 0.1 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 EKG17789.1 - 0.11 12.1 0.0 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) GRAM PF02893.15 EKG17790.1 - 1e-29 101.8 0.9 1.9e-16 59.3 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EKG17790.1 - 1.9e-22 79.4 0.0 7.5e-22 77.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EKG17790.1 - 1e-14 54.5 0.1 1e-13 51.3 0.0 2.7 2 1 1 3 3 3 1 PH domain PH_11 PF15413.1 EKG17790.1 - 5.5e-06 26.6 3.1 5.9e-06 26.5 0.3 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EKG17790.1 - 8.5e-06 25.6 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 EKG17790.1 - 0.00016 20.3 0.0 0.00034 19.3 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_BEACH PF14844.1 EKG17790.1 - 0.0011 18.8 0.0 0.49 10.2 0.0 2.7 2 0 0 2 2 2 2 PH domain associated with Beige/BEACH PH_6 PF15406.1 EKG17790.1 - 0.0063 16.5 0.0 0.024 14.6 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EKG17790.1 - 0.015 15.3 0.0 0.072 13.1 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4449 PF14613.1 EKG17791.1 - 1.9e-06 27.8 0.1 1.9e-06 27.8 0.1 2.8 5 0 0 5 5 5 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.1 EKG17791.1 - 0.011 15.5 0.8 0.097 12.5 0.2 2.8 3 0 0 3 3 3 0 Tricorn protease C1 domain DUF1828 PF08861.5 EKG17791.1 - 0.035 13.7 0.2 0.23 11.0 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF1828 Malic_M PF03949.10 EKG17792.1 - 1e-89 300.5 0.0 1.3e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EKG17792.1 - 2.3e-46 157.6 0.0 3.7e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TPT PF03151.11 EKG17793.1 - 5.6e-32 110.5 8.3 5.6e-32 110.5 5.7 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EKG17793.1 - 8.2e-06 25.8 17.9 0.0037 17.2 1.4 2.9 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EKG17793.1 - 0.023 13.6 19.1 0.0051 15.7 10.0 2.0 2 0 0 2 2 2 0 UAA transporter family DUF4366 PF14283.1 EKG17793.1 - 0.038 13.4 0.0 0.69 9.2 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) PBP1_TM PF14812.1 EKG17793.1 - 2.7 8.3 8.4 7.6 6.9 5.9 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RED_N PF07808.8 EKG17794.1 - 1.2e-07 31.2 6.7 2.8e-07 29.9 4.6 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region Glyco_hydro_43 PF04616.9 EKG17795.1 - 2.1e-34 118.9 5.6 2.6e-34 118.6 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF2722 PF10846.3 EKG17798.1 - 5e-06 25.7 14.7 5e-05 22.5 0.7 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Adeno_PX PF05829.7 EKG17798.1 - 0.0043 16.5 0.1 0.0087 15.5 0.1 1.5 1 0 0 1 1 1 1 Adenovirus late L2 mu core protein (Protein X) VIT1 PF01988.14 EKG17798.1 - 0.12 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 VIT family Melibiase PF02065.13 EKG17800.1 - 3.9e-21 75.2 0.2 3.5e-15 55.6 0.0 2.5 2 1 0 2 2 2 2 Melibiase DENN PF02141.16 EKG17800.1 - 1.6e-05 24.7 0.6 0.00014 21.6 0.4 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain Glyco_hydro_97 PF10566.4 EKG17800.1 - 0.011 14.9 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 Vac14_Fig4_bd PF11916.3 EKG17801.1 - 1.9e-83 278.0 6.0 1.9e-83 278.0 4.2 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EKG17801.1 - 2e-48 162.7 0.2 1.7e-44 150.1 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EKG17801.1 - 2.8e-12 45.5 4.4 0.00022 21.0 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EKG17801.1 - 3.3e-08 33.6 7.7 0.00026 21.1 0.1 5.6 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EKG17801.1 - 1.4e-07 31.8 9.7 0.00035 20.9 0.0 6.9 5 1 1 6 6 6 1 HEAT-like repeat Cnd1 PF12717.2 EKG17801.1 - 1.4e-05 25.0 3.1 0.083 12.7 0.0 3.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EKG17801.1 - 0.0018 18.0 0.0 11 5.9 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Kinesin PF00225.18 EKG17802.1 - 6.7e-88 294.6 0.8 1e-87 293.9 0.6 1.3 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EKG17802.1 - 8.9e-05 21.9 0.4 0.062 13.0 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EKG17802.1 - 0.0015 18.6 0.4 0.0015 18.6 0.3 2.8 2 2 0 2 2 2 1 Helix-hairpin-helix domain HHH_3 PF12836.2 EKG17802.1 - 0.019 14.8 0.2 0.6 10.0 0.1 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif zf-DNL PF05180.7 EKG17804.1 - 1.5e-29 101.4 2.5 1.9e-29 101.1 1.7 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.1 EKG17804.1 - 0.082 12.6 1.2 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EKG17804.1 - 0.16 11.5 1.6 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EKG17804.1 - 0.17 11.6 0.9 0.27 10.9 0.7 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Cullin PF00888.17 EKG17805.1 - 2.7e-136 455.5 5.5 3.7e-136 455.0 3.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EKG17805.1 - 8.5e-27 92.7 0.8 8.5e-27 92.7 0.6 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain XPG_I_2 PF12813.2 EKG17805.1 - 0.033 13.6 0.9 2.4 7.5 0.3 2.7 2 0 0 2 2 2 0 XPG domain containing Glyco_hydro_cc PF11790.3 EKG17806.1 - 1.7e-50 171.6 3.1 2.3e-50 171.2 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Macoilin PF09726.4 EKG17806.1 - 7.9 4.6 7.1 9.9 4.3 4.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DWNN PF08783.6 EKG17807.1 - 8.5e-30 102.5 0.0 1.6e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EKG17807.1 - 9.4e-07 28.2 4.1 1.6e-06 27.4 2.2 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EKG17807.1 - 0.019 14.9 8.0 0.019 14.9 5.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EKG17807.1 - 0.2 11.2 3.4 0.46 10.0 2.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EKG17807.1 - 0.41 10.3 8.3 0.92 9.2 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKG17807.1 - 0.96 9.3 8.7 2.7 7.9 6.0 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 EKG17807.1 - 4.2 7.3 9.5 0.26 11.1 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-CCHC PF00098.18 EKG17807.1 - 6.6 6.8 9.1 3.6 7.6 2.0 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-RING_4 PF14570.1 EKG17807.1 - 7.8 6.1 13.8 0.064 12.8 3.8 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EKG17807.1 - 9.3 6.0 13.6 0.25 11.0 4.7 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Sec23_trunk PF04811.10 EKG17808.1 - 6.2e-70 235.3 0.0 2.1e-69 233.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EKG17808.1 - 2.2e-23 81.6 0.0 2.9e-22 78.0 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EKG17808.1 - 8.8e-18 64.6 0.0 1.9e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EKG17808.1 - 1.2e-17 63.1 5.2 2.1e-17 62.3 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EKG17808.1 - 1.4e-09 37.5 0.0 2.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-H2C2_2 PF13465.1 EKG17809.1 - 1.8e-06 27.9 4.2 1.8e-06 27.9 2.9 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG17809.1 - 3e-06 27.1 12.7 0.003 17.7 1.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG17809.1 - 2.4e-05 24.4 14.5 0.0064 16.7 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EKG17809.1 - 0.068 13.0 0.7 0.068 13.0 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger TylF PF05711.6 EKG17809.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) LRV_FeS PF05484.6 EKG17810.1 - 0.079 12.5 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 LRV protein FeS4 cluster DRIM PF07539.7 EKG17811.1 - 4.2e-46 155.8 0.0 1.9e-45 153.7 0.0 2.3 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 EKG17811.1 - 0.0075 16.2 2.3 9.7 6.5 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 EKG17811.1 - 0.23 11.9 12.1 5 7.7 0.1 6.3 7 0 0 7 7 7 0 HEAT-like repeat CwfJ_C_1 PF04677.10 EKG17812.1 - 6.3e-24 83.9 0.0 1e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EKG17812.1 - 3.6e-23 81.8 0.1 7e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF4187 PF13821.1 EKG17813.1 - 0.086 12.4 1.0 0.17 11.5 0.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4187) Sua5_yciO_yrdC PF01300.13 EKG17814.1 - 1.8e-51 173.9 0.0 2.8e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EKG17814.1 - 1.6e-26 92.8 0.0 6.6e-26 90.8 0.0 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Fungal_trans_2 PF11951.3 EKG17815.1 - 2.2e-06 26.5 0.5 5.9e-06 25.1 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1206 PF06724.6 EKG17815.1 - 0.045 13.5 0.4 0.086 12.6 0.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) PMC2NT PF08066.7 EKG17815.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DNA_primase_S PF01896.14 EKG17816.1 - 6.2e-53 178.4 0.0 9.8e-53 177.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF1917 PF08939.5 EKG17817.1 - 5.9e-52 176.8 0.0 7.9e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Herpes_TK_C PF08465.5 EKG17817.1 - 0.13 11.7 0.1 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Exo_endo_phos PF03372.18 EKG17819.1 - 2e-10 41.0 0.1 2.2e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EKG17819.1 - 0.067 12.7 0.0 0.42 10.2 0.0 2.2 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Peptidase_M24 PF00557.19 EKG17820.1 - 3.2e-11 43.1 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 NusA_N PF08529.6 EKG17820.1 - 0.051 13.5 2.1 0.11 12.4 0.6 2.1 2 0 0 2 2 2 0 NusA N-terminal domain DUF977 PF06163.6 EKG17820.1 - 0.1 12.3 0.4 0.68 9.6 0.0 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF977) DUF1122 PF06557.6 EKG17820.1 - 0.12 11.4 0.1 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) UBA_3 PF09288.5 EKG17821.1 - 0.13 11.8 0.3 0.72 9.5 0.0 2.3 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain PHD PF00628.24 EKG17822.1 - 3.4e-16 58.6 21.8 1.9e-09 37.0 8.3 2.5 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 EKG17822.1 - 5.1e-06 26.1 0.7 5.1e-06 26.1 0.5 2.7 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 EKG17822.1 - 3.4e-05 23.8 5.0 0.056 13.5 0.7 2.6 2 0 0 2 2 2 2 PHD-like zinc-binding domain zinc_ribbon_2 PF13240.1 EKG17822.1 - 0.0024 17.3 1.7 1.7 8.2 0.3 2.5 2 0 0 2 2 2 2 zinc-ribbon domain C1_1 PF00130.17 EKG17822.1 - 0.0025 17.5 2.1 0.0025 17.5 1.4 2.7 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EKG17822.1 - 0.27 10.5 21.1 0.037 13.3 3.2 3.4 4 0 0 4 4 4 0 PHD-finger zf-PHD-like PF15446.1 EKG17822.1 - 0.39 9.9 13.7 0.15 11.3 1.2 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Ribosomal_L37e PF01907.14 EKG17822.1 - 0.56 10.0 4.7 0.86 9.4 0.3 2.4 2 0 0 2 2 2 0 Ribosomal protein L37e zf-HC5HC2H_2 PF13832.1 EKG17822.1 - 0.71 9.8 8.9 1.8 8.5 0.7 2.8 3 0 0 3 3 3 0 PHD-zinc-finger like domain Hep_59 PF07052.6 EKG17823.1 - 1.9e-14 53.9 0.2 1.9e-14 53.9 0.1 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 HA2 PF04408.18 EKG17824.1 - 2.9e-18 65.7 0.1 7.8e-18 64.3 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKG17824.1 - 9.8e-12 44.5 0.1 2.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG17824.1 - 3.8e-09 36.2 0.0 8.1e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKG17824.1 - 4.4e-08 33.3 0.0 2e-07 31.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 EKG17824.1 - 5.2e-07 29.4 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC_tran PF00005.22 EKG17824.1 - 0.00088 19.5 0.1 0.007 16.6 0.0 2.6 3 0 0 3 3 3 1 ABC transporter FtsK_SpoIIIE PF01580.13 EKG17824.1 - 0.0073 15.8 0.0 0.064 12.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NB-ARC PF00931.17 EKG17824.1 - 0.052 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EKG17824.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EKG17824.1 - 0.064 12.7 0.0 0.18 11.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EKG17824.1 - 0.14 11.3 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3554 PF12074.3 EKG17825.1 - 4.7e-78 262.9 0.3 4.7e-78 262.9 0.2 4.1 4 1 1 5 5 5 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EKG17825.1 - 1.4e-40 137.4 60.7 2.5e-09 37.3 0.0 17.3 7 3 12 19 19 19 14 HEAT repeats HEAT_EZ PF13513.1 EKG17825.1 - 3.2e-38 129.2 65.1 6.8e-05 23.2 0.0 24.6 17 4 8 26 26 25 11 HEAT-like repeat HEAT PF02985.17 EKG17825.1 - 5.5e-36 119.4 37.0 0.039 14.0 0.1 22.3 25 0 0 25 25 24 8 HEAT repeat Vac14_Fab1_bd PF12755.2 EKG17825.1 - 1.5e-15 57.3 0.1 1 9.7 0.0 9.5 7 4 4 11 11 11 5 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EKG17825.1 - 1.3e-13 50.1 0.7 6.3e-06 24.7 0.0 6.3 5 2 0 5 5 5 3 Adaptin N terminal region ParcG PF10274.4 EKG17825.1 - 2.2e-12 47.2 4.0 0.00094 19.1 0.0 7.3 7 1 1 8 8 8 2 Parkin co-regulated protein Cnd1 PF12717.2 EKG17825.1 - 1.2e-11 44.7 0.1 0.53 10.1 0.0 7.8 6 2 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EKG17825.1 - 1.9e-10 40.5 0.0 0.19 11.0 0.0 5.8 3 2 1 5 5 5 3 CLASP N terminal UME PF08064.8 EKG17825.1 - 1.1e-06 28.5 1.2 9.8 6.1 0.0 8.3 7 2 2 10 10 10 1 UME (NUC010) domain MMS19_C PF12460.3 EKG17825.1 - 0.0027 16.5 15.1 0.058 12.1 0.0 5.9 5 2 0 5 5 5 2 RNAPII transcription regulator C-terminal GPI2 PF06432.6 EKG17825.1 - 0.015 14.7 0.3 0.028 13.7 0.2 1.4 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase FANCI_S2 PF14676.1 EKG17825.1 - 0.024 14.5 0.7 5.9 6.7 0.0 4.0 4 0 0 4 4 4 0 FANCI solenoid 2 Vitellogenin_N PF01347.17 EKG17825.1 - 0.025 12.8 0.0 0.06 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein amino terminal region U3snoRNP10 PF12397.3 EKG17825.1 - 0.29 11.0 6.2 27 4.7 0.0 6.3 7 1 1 8 8 7 0 U3 small nucleolar RNA-associated protein 10 SAGA-Tad1 PF12767.2 EKG17826.1 - 5.1e-53 180.3 0.0 6.8e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Hexokinase_2 PF03727.11 EKG17827.1 - 1.3e-88 296.3 0.0 1.8e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EKG17827.1 - 2.4e-77 258.8 0.0 4.1e-77 258.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Abhydrolase_5 PF12695.2 EKG17831.1 - 3.6e-16 59.2 0.0 5.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG17831.1 - 2.7e-15 56.8 1.5 3.4e-15 56.5 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EKG17831.1 - 1.1e-13 50.5 0.0 1.7e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.15 EKG17831.1 - 2e-06 27.4 0.0 3.1e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EKG17831.1 - 1.6e-05 24.5 0.1 0.0016 18.0 0.1 2.5 1 1 1 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EKG17831.1 - 2.5e-05 23.8 0.1 4.2e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EKG17831.1 - 0.00011 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 EKG17831.1 - 0.00047 19.9 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EKG17831.1 - 0.0026 17.0 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family RTA1 PF04479.8 EKG17834.1 - 4.6e-57 193.0 9.5 6.6e-57 192.6 6.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 EKG17835.1 - 2.1e-05 23.2 0.1 2.7e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Band_7 PF01145.20 EKG17836.1 - 6.7e-27 94.5 2.3 1.2e-26 93.7 1.6 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EKG17836.1 - 0.011 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Adaptin_N PF01602.15 EKG17837.1 - 1.2e-147 492.4 0.4 1.5e-147 492.1 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EKG17837.1 - 7.2e-28 97.6 0.2 3e-25 89.1 0.1 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EKG17837.1 - 3.2e-18 65.8 0.0 4.7e-06 26.7 0.0 5.1 2 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EKG17837.1 - 6.7e-10 38.2 9.2 0.021 14.8 0.0 6.3 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EKG17837.1 - 3.4e-06 27.3 0.1 1.2 9.6 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 EKG17837.1 - 0.00029 20.5 1.6 14 5.7 0.0 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EKG17837.1 - 0.0037 16.6 0.1 1.7 7.9 0.0 3.6 2 1 0 2 2 2 1 CLASP N terminal Cohesin_HEAT PF12765.2 EKG17837.1 - 0.0066 16.3 0.8 16 5.6 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Mito_carr PF00153.22 EKG17838.1 - 1.5e-37 127.1 0.7 1.4e-18 66.3 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3824 PF12868.2 EKG17839.1 - 3.5e-17 63.6 46.1 3.5e-17 63.6 32.0 7.8 5 4 3 8 8 8 3 Domain of unknwon function (DUF3824) DUF533 PF04391.7 EKG17839.1 - 0.98 8.7 20.5 0.087 12.1 1.9 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF533) MSC PF09402.5 EKG17840.1 - 9.4e-89 297.4 0.0 1.3e-88 296.9 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EKG17840.1 - 1.5e-17 62.8 0.1 2.9e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 EKG17840.1 - 8.1e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 Thymopoietin protein Ashwin PF15323.1 EKG17840.1 - 0.57 10.1 16.2 0.06 13.3 7.8 1.8 2 0 0 2 2 2 0 Developmental protein Ribosomal_L44 PF00935.14 EKG17841.1 - 1.5e-33 114.5 8.3 2.5e-33 113.9 5.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 MRJP PF03022.11 EKG17842.1 - 4.2e-32 111.4 0.0 5.4e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EKG17842.1 - 0.0002 20.8 0.2 0.013 14.8 0.1 2.6 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EKG17842.1 - 0.014 15.3 3.2 7.4 6.7 0.0 4.6 5 0 0 5 5 5 0 NHL repeat IMS PF00817.15 EKG17843.1 - 1.9e-38 131.5 0.1 5.6e-38 130.0 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EKG17843.1 - 7.9e-19 67.8 0.0 2.1e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EKG17843.1 - 6.1e-14 51.8 4.3 9.2e-05 22.3 0.2 5.2 4 1 1 5 5 5 3 Domain of unknown function (DUF4414) BRCT PF00533.21 EKG17843.1 - 1.8e-07 31.1 0.0 4.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKG17843.1 - 8e-06 25.6 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EKG17843.1 - 0.00024 20.9 0.3 0.002 18.0 0.1 2.7 2 0 0 2 2 2 1 IMS family HHH motif AT_hook PF02178.14 EKG17843.1 - 0.012 15.1 2.5 0.08 12.6 1.8 2.6 1 0 0 1 1 1 0 AT hook motif FKBP_C PF00254.23 EKG17844.1 - 3.3e-32 110.3 0.7 2.8e-31 107.3 0.0 2.6 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase Yippee-Mis18 PF03226.9 EKG17845.1 - 9.8e-17 60.7 0.0 1.2e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Pkinase PF00069.20 EKG17846.1 - 1.3e-47 162.1 1.0 3.1e-26 92.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EKG17846.1 - 1.6e-22 79.8 1.0 1.4e-12 47.2 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKG17846.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 EKG17846.1 - 0.048 13.4 0.2 0.096 12.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ERF PF04404.7 EKG17846.1 - 0.089 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 ERF superfamily Inositol_P PF00459.20 EKG17847.1 - 5.2e-61 206.3 0.0 6.9e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family 3HCDH_N PF02737.13 EKG17849.1 - 6.5e-29 100.8 0.0 1.9e-28 99.3 0.0 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EKG17849.1 - 2.4e-11 43.8 0.0 5.2e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AMP-binding_C PF13193.1 EKG17850.1 - 2.4e-15 57.2 0.5 3.4e-15 56.7 0.3 1.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EKG17850.1 - 1.7e-13 49.7 0.3 2.3e-13 49.3 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP2C PF00481.16 EKG17851.1 - 4.5e-52 176.9 0.0 9.5e-52 175.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EKG17851.1 - 2.7e-47 157.6 56.6 1.1e-06 28.0 0.6 13.8 6 3 7 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG17851.1 - 1.6e-42 143.0 53.0 9.1e-10 38.1 0.1 11.0 5 4 3 10 10 10 8 Leucine rich repeat Guanylate_cyc PF00211.15 EKG17851.1 - 4.6e-30 104.3 0.0 1.1e-29 103.1 0.0 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EKG17851.1 - 8.2e-26 86.0 48.2 0.67 10.2 0.0 19.5 20 1 1 21 21 21 9 Leucine Rich Repeat RA PF00788.18 EKG17851.1 - 1.4e-12 47.8 0.0 6.7e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 EKG17851.1 - 3e-09 35.5 61.6 4.8 7.8 0.3 17.9 19 0 0 19 19 19 5 Leucine rich repeat Ad_cyc_g-alpha PF08509.6 EKG17851.1 - 6.1e-08 31.8 0.9 1.9e-07 30.3 0.6 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_6 PF13516.1 EKG17851.1 - 2.4e-05 23.9 45.6 16 5.9 0.1 16.5 17 1 1 18 18 18 0 Leucine Rich repeat LRR_5 PF13306.1 EKG17851.1 - 0.00074 19.2 0.4 0.24 11.1 0.1 3.4 3 0 0 3 3 3 1 Leucine rich repeats (6 copies) TMEMspv1-c74-12 PF11044.3 EKG17852.1 - 0.41 10.2 1.8 0.76 9.3 1.2 1.5 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein CcoS PF03597.10 EKG17852.1 - 1.2 8.6 3.5 1.7 8.1 2.5 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type zf-UBR PF02207.15 EKG17853.1 - 3.1e-14 52.4 6.6 3.1e-14 52.4 4.6 3.6 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 EKG17854.1 - 2.3e-139 463.8 0.1 3.1e-139 463.4 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EKG17854.1 - 2.6e-36 124.9 40.7 2.6e-36 124.9 28.2 2.1 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EKG17854.1 - 1.4e-20 73.9 0.1 3.3e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKG17854.1 - 1.3e-08 34.3 0.0 1.7e-06 27.3 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKG17854.1 - 1.8e-05 24.4 0.0 4.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EKG17854.1 - 0.0003 20.2 0.3 0.002 17.6 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EKG17854.1 - 0.00068 19.2 0.1 0.0034 16.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FAM92 PF06730.6 EKG17854.1 - 0.011 15.0 3.0 0.025 13.9 2.1 1.5 1 0 0 1 1 1 0 FAM92 protein Sigma54_activ_2 PF14532.1 EKG17854.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2457 PF10446.4 EKG17855.1 - 1.1 7.9 10.9 1.5 7.5 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EKG17855.1 - 3.5 6.0 10.0 4.7 5.5 6.9 1.1 1 0 0 1 1 1 0 Daxx Family PhzC-PhzF PF02567.11 EKG17856.1 - 3.8e-39 134.5 0.0 5.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Band_7 PF01145.20 EKG17859.1 - 2.1e-15 57.0 0.0 2.1e-15 57.0 0.0 2.8 2 1 1 3 3 3 1 SPFH domain / Band 7 family AAA_15 PF13175.1 EKG17859.1 - 0.043 12.8 0.6 0.08 11.9 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain Mago-bind PF09282.5 EKG17861.1 - 1.4e-14 53.3 3.7 2.6e-14 52.4 2.5 1.5 1 0 0 1 1 1 1 Mago binding UCR_UQCRX_QCR9 PF05365.7 EKG17862.1 - 4e-24 83.9 0.2 7.3e-24 83.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4185 PF13810.1 EKG17862.1 - 0.098 11.5 0.1 0.097 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) zf-UBR PF02207.15 EKG17863.1 - 3.4e-18 65.1 12.6 3.4e-18 65.1 8.7 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EKG17863.1 - 5e-06 26.1 0.1 1.6e-05 24.5 0.1 1.9 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Rpn3_C PF08375.6 EKG17865.1 - 1.4e-24 86.2 1.9 2.6e-24 85.4 1.3 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EKG17865.1 - 3.9e-22 78.5 0.1 3.2e-21 75.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EKG17865.1 - 0.0078 15.9 0.4 0.2 11.4 0.3 2.5 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EKG17865.1 - 0.011 15.5 0.0 0.049 13.5 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DASH_Spc34 PF08657.5 EKG17866.1 - 4.1e-53 180.7 0.2 1e-25 90.9 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 IncA PF04156.9 EKG17866.1 - 2.7 7.5 7.6 9.7 5.7 5.5 1.6 1 1 0 1 1 1 0 IncA protein KilA-N PF04383.8 EKG17868.1 - 0.00025 20.6 0.0 0.0027 17.2 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain Ank_2 PF12796.2 EKG17869.1 - 2.2e-21 76.0 1.3 5.6e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKG17869.1 - 3.1e-17 61.4 8.4 6e-07 28.9 0.9 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EKG17869.1 - 1.5e-16 59.9 8.8 1.1e-07 31.8 1.5 4.3 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG17869.1 - 2.5e-12 46.9 4.5 1.8e-06 28.2 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG17869.1 - 1.3e-10 40.4 3.9 0.031 14.5 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat WD40 PF00400.27 EKG17870.1 - 2.2e-07 30.4 0.4 0.44 10.5 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Herpes_UL32 PF06070.6 EKG17870.1 - 0.0092 14.5 0.4 0.013 13.9 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus large structural phosphoprotein UL32 PD40 PF07676.7 EKG17870.1 - 0.034 13.8 0.0 10 5.9 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_transf_20 PF00982.16 EKG17871.1 - 1.9e-152 508.0 0.0 2.7e-152 507.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EKG17871.1 - 1.4e-89 299.0 0.0 7.9e-89 296.5 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EKG17871.1 - 2.8e-06 27.1 0.0 0.032 13.8 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG17871.1 - 0.085 13.0 0.0 1.3 9.1 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PAP_assoc PF03828.14 EKG17872.1 - 1.2e-06 28.3 0.0 3.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EKG17872.1 - 0.0098 16.1 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain p450 PF00067.17 EKG17873.1 - 2.4e-25 89.0 0.0 5.7e-18 64.6 0.0 2.3 2 1 0 2 2 2 2 Cytochrome P450 WW PF00397.21 EKG17874.1 - 0.00035 20.3 0.2 0.00057 19.6 0.1 1.4 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 EKG17874.1 - 0.99 9.4 15.2 1.9 8.4 10.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Peptidase_A22B PF04258.8 EKG17876.1 - 9.9e-59 199.2 0.0 2.4e-58 197.9 0.0 1.5 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EKG17876.1 - 2.2e-08 33.5 1.2 2.2e-08 33.5 0.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1119) DUF4131 PF13567.1 EKG17876.1 - 0.012 14.9 0.4 0.78 9.1 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Glycophorin_A PF01102.13 EKG17876.1 - 0.016 14.9 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A LigB PF02900.13 EKG17877.1 - 1.3e-50 171.9 0.0 1.4e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF4071 PF13281.1 EKG17877.1 - 0.073 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) L51_S25_CI-B8 PF05047.11 EKG17878.1 - 3.7e-14 52.1 0.0 4.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EKG17879.1 - 5.7e-19 68.2 0.0 6.4e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) GMC_oxred_N PF00732.14 EKG17880.1 - 1.8e-60 204.6 0.1 2.1e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG17880.1 - 1.8e-11 44.5 0.0 3.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG17880.1 - 3.7e-05 22.7 0.0 0.14 10.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EKG17880.1 - 0.00067 18.6 1.6 0.0017 17.3 1.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG17880.1 - 0.0026 18.1 0.3 0.5 10.8 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG17880.1 - 0.0044 15.9 0.1 0.0062 15.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG17880.1 - 0.0085 16.0 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF2316 PF10078.4 EKG17881.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Lipase_GDSL_2 PF13472.1 EKG17882.1 - 9.6e-13 48.6 1.7 9.6e-13 48.6 1.2 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EKG17882.1 - 6.5e-06 26.1 5.5 4.3e-05 23.4 3.8 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EKG17882.1 - 0.0051 16.5 1.0 0.014 15.0 0.1 2.1 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CHB_HEX_C_1 PF13290.1 EKG17882.1 - 0.083 12.6 0.4 0.2 11.4 0.3 1.6 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF2365 PF10157.4 EKG17883.1 - 3.5e-05 23.7 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) COG5 PF10392.4 EKG17883.1 - 0.0068 16.3 0.9 0.04 13.8 0.3 2.0 1 1 1 2 2 2 1 Golgi transport complex subunit 5 Not3 PF04065.10 EKG17883.1 - 0.026 13.8 0.2 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component ATP-synt_D PF01813.12 EKG17883.1 - 0.034 13.6 0.7 0.079 12.4 0.3 1.7 1 1 0 1 1 1 0 ATP synthase subunit D CHASE3 PF05227.8 EKG17883.1 - 0.1 12.2 3.6 0.26 10.9 1.6 2.1 1 1 1 2 2 2 0 CHASE3 domain Spectrin PF00435.16 EKG17883.1 - 0.14 12.4 2.3 13 6.0 0.7 2.6 1 1 1 2 2 2 0 Spectrin repeat Copper-bind PF00127.15 EKG17884.1 - 3.9e-05 23.8 0.1 6.7e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EKG17884.1 - 0.00097 18.8 0.1 0.0024 17.6 0.1 1.6 1 1 0 1 1 1 1 Plastocyanin-like domain DUF1206 PF06724.6 EKG17884.1 - 0.27 11.0 7.6 0.63 9.8 5.3 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) GATA PF00320.22 EKG17886.1 - 9.9e-17 60.0 2.1 1.9e-16 59.0 1.5 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EKG17886.1 - 6e-13 48.1 5.8 1.1e-12 47.3 4.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Osmo_CC PF08946.5 EKG17888.1 - 0.0057 16.6 0.8 0.044 13.8 0.1 2.1 1 1 1 2 2 2 1 Osmosensory transporter coiled coil DUF2968 PF11180.3 EKG17888.1 - 0.021 14.1 0.3 0.034 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) PaaX_C PF08223.6 EKG17888.1 - 0.068 12.8 0.1 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 PaaX-like protein C-terminal domain XhlA PF10779.4 EKG17888.1 - 0.58 10.1 5.2 0.71 9.8 0.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF619 PF04768.8 EKG17889.1 - 2.1e-47 160.7 0.1 3.9e-47 159.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EKG17889.1 - 5.1e-31 107.4 0.0 3.3e-30 104.8 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EKG17889.1 - 1.2e-24 87.1 0.0 2.3e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EKG17889.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EKG17889.1 - 0.025 15.0 0.0 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Synaptobrevin PF00957.16 EKG17890.1 - 5.4e-33 112.4 0.8 6.3e-33 112.2 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin Glyco_hydro_76 PF03663.9 EKG17891.1 - 1.3e-150 501.9 18.9 1.6e-150 501.6 13.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EKG17891.1 - 0.19 10.7 9.8 0.072 12.1 0.2 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 His_Phos_1 PF00300.17 EKG17892.1 - 3.1e-31 108.6 0.3 3.7e-31 108.3 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) NAC PF01849.13 EKG17896.1 - 6.7e-09 35.1 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 NAC domain SMC_N PF02463.14 EKG17897.1 - 2.1e-25 89.2 0.0 4.6e-25 88.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKG17897.1 - 1.4e-11 45.1 76.2 3.2e-11 43.9 21.0 5.4 3 2 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EKG17897.1 - 1.8e-07 31.4 3.2 0.0002 21.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EKG17897.1 - 0.00018 20.9 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EKG17897.1 - 0.002 17.2 0.0 0.002 17.2 0.0 3.4 4 1 0 4 4 4 1 AAA ATPase domain AAA_25 PF13481.1 EKG17897.1 - 0.032 13.6 0.0 0.032 13.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Vac_Fusion PF02346.11 EKG17897.1 - 0.042 13.2 0.1 0.042 13.2 0.1 3.8 3 0 0 3 3 3 0 Chordopoxvirus fusion protein AAA_19 PF13245.1 EKG17897.1 - 0.098 12.4 0.2 0.44 10.3 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Baculo_PEP_C PF04513.7 EKG17897.1 - 0.35 10.6 21.9 7.8 6.3 0.9 5.4 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EKG17897.1 - 0.52 10.5 0.0 0.52 10.5 0.0 5.9 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein AAA_17 PF13207.1 EKG17897.1 - 0.6 10.9 0.0 0.6 10.9 0.0 5.0 3 2 0 4 4 2 0 AAA domain Reo_sigmaC PF04582.7 EKG17897.1 - 3.3 6.8 6.5 20 4.2 0.1 3.8 2 2 4 6 6 6 0 Reovirus sigma C capsid protein Sgf11 PF08209.6 EKG17898.1 - 8.7e-12 44.1 1.8 1.1e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EKG17898.1 - 0.024 14.3 1.5 0.024 14.3 1.0 1.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FMN_dh PF01070.13 EKG17900.1 - 1.5e-64 218.1 0.3 1.7e-64 217.9 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EKG17900.1 - 0.00011 21.4 0.3 0.00014 21.0 0.2 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EKG17900.1 - 0.00017 20.7 0.2 0.054 12.5 0.0 2.1 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EKG17900.1 - 0.0015 17.5 0.1 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EKG17900.1 - 0.012 14.5 2.1 0.023 13.6 0.1 2.1 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain Pex14_N PF04695.8 EKG17901.1 - 0.14 12.1 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WSC PF01822.14 EKG17902.1 - 3.6e-37 126.1 54.3 1.3e-17 63.4 11.1 4.5 5 0 0 5 5 5 3 WSC domain PAN_4 PF14295.1 EKG17902.1 - 5.8e-07 29.1 0.3 5.8e-07 29.1 0.2 5.6 6 0 0 6 6 6 2 PAN domain Abhydrolase_5 PF12695.2 EKG17902.1 - 0.00089 19.0 0.7 0.0087 15.8 0.4 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAN_3 PF08277.7 EKG17902.1 - 0.23 11.0 7.7 0.16 11.6 0.2 3.9 4 0 0 4 4 4 0 PAN-like domain Methyltransf_23 PF13489.1 EKG17903.1 - 7.1e-16 58.3 0.1 1.3e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG17903.1 - 1.1e-09 38.8 0.0 1e-08 35.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG17903.1 - 4.6e-06 26.2 0.0 3.4e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG17903.1 - 2e-05 24.9 0.0 6.9e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG17903.1 - 8.2e-05 23.0 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG17903.1 - 0.00075 19.8 0.0 0.0026 18.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EKG17903.1 - 0.005 16.3 0.0 0.0094 15.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EKG17903.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EKG17903.1 - 0.016 14.2 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EKG17903.1 - 0.044 12.9 0.0 0.27 10.3 0.0 2.2 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EKG17903.1 - 0.055 12.8 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 EKG17903.1 - 0.1 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF938 PF06080.7 EKG17903.1 - 0.17 11.4 0.0 0.46 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.13 EKG17904.1 - 2.3e-27 95.7 0.1 3.8e-27 95.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EKG17904.1 - 0.0012 18.6 0.0 0.0042 16.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain HisKA_3 PF07730.8 EKG17904.1 - 0.08 13.3 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase Pectate_lyase PF03211.8 EKG17907.1 - 1.8e-68 230.1 8.6 2.3e-68 229.8 6.0 1.0 1 0 0 1 1 1 1 Pectate lyase Glyco_transf_54 PF04666.8 EKG17908.1 - 0.0054 15.5 0.1 0.15 10.7 0.0 2.6 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region p450 PF00067.17 EKG17909.1 - 1.4e-20 73.3 0.0 7.1e-14 51.1 0.0 2.8 2 1 1 3 3 3 2 Cytochrome P450 But2 PF09792.4 EKG17911.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF1295 PF06966.7 EKG17912.1 - 1.5e-31 109.4 0.0 2.2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EKG17912.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 EKG17912.1 - 0.0044 17.1 0.0 0.0086 16.2 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EKG17912.1 - 0.043 13.5 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase HflK_N PF12221.3 EKG17912.1 - 0.17 11.6 22.2 11 5.8 0.1 7.7 8 0 0 8 8 8 0 Bacterial membrane protein N terminal ERG4_ERG24 PF01222.12 EKG17912.1 - 0.23 9.9 0.0 0.37 9.2 0.0 1.3 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Aminotran_1_2 PF00155.16 EKG17913.1 - 6.3e-67 226.0 0.0 7.1e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EKG17913.1 - 4.2e-08 32.6 0.0 6.6e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EKG17913.1 - 1.1e-06 28.0 0.0 1.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EKG17913.1 - 0.00047 18.5 0.0 0.001 17.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EKG17913.1 - 0.0029 16.4 0.0 0.0097 14.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V MgsA_C PF12002.3 EKG17914.1 - 4.2e-59 198.9 0.0 6.5e-59 198.3 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EKG17914.1 - 3.1e-14 53.3 0.0 8.7e-14 51.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EKG17914.1 - 5.8e-11 41.8 0.0 1.7e-10 40.3 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EKG17914.1 - 4.1e-06 26.4 0.3 1.6e-05 24.5 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_5 PF07728.9 EKG17914.1 - 1.2e-05 25.0 0.0 0.00041 20.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG17914.1 - 3.5e-05 23.9 0.3 0.00021 21.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EKG17914.1 - 7.5e-05 22.2 0.0 0.0029 17.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EKG17914.1 - 8.6e-05 21.7 0.1 0.11 11.6 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EKG17914.1 - 0.00011 23.0 0.0 0.0003 21.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EKG17914.1 - 0.00013 21.5 0.0 0.00044 19.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EKG17914.1 - 0.00057 19.9 0.0 0.0016 18.5 0.0 1.7 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_16 PF13191.1 EKG17914.1 - 0.0019 18.1 1.5 0.074 13.0 0.0 3.4 3 1 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 EKG17914.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EKG17914.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase AAA_28 PF13521.1 EKG17914.1 - 0.0067 16.4 0.4 0.016 15.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EKG17914.1 - 0.009 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RecO_C PF02565.10 EKG17914.1 - 0.015 15.1 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 Recombination protein O C terminal TIP49 PF06068.8 EKG17914.1 - 0.028 13.1 0.0 0.064 11.9 0.0 1.4 1 1 0 1 1 1 0 TIP49 C-terminus ResIII PF04851.10 EKG17914.1 - 0.035 13.9 0.2 3.5 7.3 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 EKG17914.1 - 0.042 13.2 0.4 9.4 5.5 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain AAA_18 PF13238.1 EKG17914.1 - 0.054 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKG17914.1 - 0.058 12.7 0.0 0.18 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKG17914.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.12 EKG17914.1 - 0.18 10.6 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PAPA-1 PF04795.7 EKG17915.1 - 1.8e-24 86.2 3.4 1.8e-24 86.2 2.3 3.4 4 2 1 5 5 5 1 PAPA-1-like conserved region Herpes_BLLF1 PF05109.8 EKG17915.1 - 0.46 8.3 5.4 0.61 7.9 3.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RNA_pol_3_Rpc31 PF11705.3 EKG17915.1 - 0.59 10.0 54.8 0.036 14.0 11.8 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Pex14_N PF04695.8 EKG17916.1 - 2.3e-24 86.0 0.0 2.3e-24 86.0 0.0 2.9 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Neisseria_TspB PF05616.8 EKG17916.1 - 9.5 4.4 9.3 14 3.9 6.4 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein GFO_IDH_MocA PF01408.17 EKG17917.1 - 1.2e-26 93.6 0.7 1.8e-26 93.0 0.5 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EKG17917.1 - 4.3e-06 26.4 0.1 2.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EKG17917.1 - 0.00089 19.6 0.1 0.0021 18.4 0.1 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain CoA_binding PF02629.14 EKG17917.1 - 0.05 14.1 0.3 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain NAD_binding_7 PF13241.1 EKG17917.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EKG17917.1 - 0.094 12.5 0.0 0.23 11.3 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 EKG17918.1 - 2.9e-17 62.4 0.1 5.1e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EKG17919.1 - 5.9e-32 110.8 1.3 8.8e-32 110.3 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG17919.1 - 1.7e-21 77.1 0.0 2.3e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG17919.1 - 1.4e-13 50.9 0.4 2.2e-13 50.2 0.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG17919.1 - 0.0001 21.8 0.1 0.00016 21.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG17919.1 - 0.00074 19.2 0.1 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EKG17919.1 - 0.027 14.4 0.6 0.05 13.6 0.4 1.6 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EKG17919.1 - 0.032 13.3 0.0 0.064 12.3 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 EKG17919.1 - 0.033 13.4 0.1 0.059 12.6 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Glyco_transf_5 PF08323.6 EKG17919.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF706 PF05153.10 EKG17920.1 - 2.9e-130 433.0 4.2 2.9e-130 433.0 2.9 1.4 2 0 0 2 2 2 1 Family of unknown function (DUF706) HD PF01966.17 EKG17920.1 - 0.057 13.4 4.9 0.36 10.8 0.4 3.1 2 2 0 2 2 2 0 HD domain SIMPL PF04402.9 EKG17920.1 - 0.19 11.5 1.7 0.31 10.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Enolase_C PF00113.17 EKG17920.1 - 0.71 8.7 3.9 0.45 9.4 0.3 2.0 2 0 0 2 2 2 0 Enolase, C-terminal TIM barrel domain Aldo_ket_red PF00248.16 EKG17921.1 - 6.8e-53 179.3 0.0 8.2e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cytochrom_C PF00034.16 EKG17922.1 - 1e-08 35.8 0.0 1.6e-08 35.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EKG17922.1 - 1.5e-08 34.6 1.4 1.2e-07 31.7 1.0 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EKG17922.1 - 0.0006 19.2 0.2 0.012 15.0 0.1 2.2 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 EKG17922.1 - 0.042 13.5 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C1 family Cytochrome-c551 PF10643.4 EKG17922.1 - 0.12 11.6 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 adh_short PF00106.20 EKG17923.1 - 6.8e-22 78.1 0.0 9.2e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG17923.1 - 1.8e-09 37.7 0.0 2.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG17923.1 - 8.3e-08 32.1 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG17923.1 - 0.0004 20.4 0.0 0.00061 19.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG17923.1 - 0.00079 18.9 0.1 0.0021 17.5 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EKG17925.1 - 2.7e-15 55.9 21.4 3.5e-15 55.5 14.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EKG17925.1 - 0.002 17.8 4.5 0.0074 16.0 0.2 3.1 3 0 0 3 3 3 1 MFS_1 like family TauD PF02668.11 EKG17926.1 - 5.2e-56 190.1 1.0 6.2e-56 189.9 0.7 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ATG_C PF09333.6 EKG17926.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 ATG C terminal domain OSCP PF00213.13 EKG17927.1 - 1.3e-43 148.8 1.6 1.3e-43 148.8 1.1 1.3 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit DUF148 PF02520.12 EKG17927.1 - 0.0081 15.9 0.9 0.42 10.4 0.5 2.2 1 1 1 2 2 2 1 Domain of unknown function DUF148 DUF3157 PF11355.3 EKG17927.1 - 0.077 12.2 1.7 0.15 11.3 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3157) ATP-synt_ab PF00006.20 EKG17928.1 - 2.3e-61 207.0 0.0 2.9e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EKG17928.1 - 3.1e-16 59.8 0.1 5.7e-16 58.9 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain LIM_bind PF01803.11 EKG17929.1 - 2e-64 217.0 1.9 3.4e-64 216.2 1.3 1.4 1 0 0 1 1 1 1 LIM-domain binding protein DUF3726 PF12525.3 EKG17930.1 - 0.086 12.6 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3726) HLH PF00010.21 EKG17932.1 - 5.7e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3678 PF12435.3 EKG17932.1 - 4.6 6.8 8.4 7.4 6.2 1.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) HMGL-like PF00682.14 EKG17934.1 - 3.8e-71 239.4 0.4 6.6e-71 238.7 0.3 1.4 1 0 0 1 1 1 1 HMGL-like ATE_C PF04377.10 EKG17935.1 - 2.1e-45 153.8 1.1 3.1e-45 153.3 0.8 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EKG17935.1 - 8.7e-18 63.9 0.4 3.1e-16 58.9 0.1 2.4 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus NUDIX PF00293.23 EKG17936.1 - 4.7e-18 65.1 0.2 5.6e-18 64.8 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S8e PF01201.17 EKG17937.1 - 8.9e-47 158.5 3.4 1.1e-46 158.2 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EKG17937.1 - 0.043 14.0 3.4 0.16 12.2 2.3 2.0 1 1 0 1 1 1 0 Small acidic protein family ALIX_LYPXL_bnd PF13949.1 EKG17938.1 - 0.0042 16.0 3.2 0.47 9.3 0.2 2.3 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV ATP-synt PF00231.14 EKG17938.1 - 0.011 15.1 2.0 0.08 12.2 0.3 2.2 2 0 0 2 2 2 0 ATP synthase Methyltransf_23 PF13489.1 EKG17939.1 - 2.6e-17 62.9 0.0 4.4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG17939.1 - 7.9e-11 42.5 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG17939.1 - 9.5e-09 35.6 0.0 2e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG17939.1 - 4.9e-07 29.4 0.0 9.9e-07 28.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG17939.1 - 1.5e-06 28.5 0.0 2.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG17939.1 - 0.00029 20.8 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKG17939.1 - 0.0043 16.6 0.0 0.009 15.5 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.7 EKG17939.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.13 EKG17939.1 - 0.017 14.2 0.0 0.07 12.2 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EKG17939.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EKG17939.1 - 0.14 10.8 0.0 0.33 9.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Glycoprotein_B PF00606.13 EKG17940.1 - 0.12 10.3 1.1 0.16 9.9 0.8 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B FAD_binding_1 PF00667.15 EKG17941.1 - 5e-47 160.1 0.0 1e-46 159.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EKG17941.1 - 3.4e-27 95.1 0.0 6.7e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EKG17941.1 - 2.7e-20 72.9 0.1 7.5e-20 71.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EKG17941.1 - 0.16 11.8 0.0 1.5 8.6 0.0 2.2 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Fungal_trans_2 PF11951.3 EKG17942.1 - 1.7e-10 40.0 0.0 2.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17942.1 - 1.1e-08 34.8 9.1 1.1e-08 34.8 6.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_1 PF00133.17 EKG17944.1 - 3.4e-38 131.0 0.0 6e-29 100.5 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EKG17944.1 - 1.9e-16 59.7 0.0 8.2e-10 37.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EKG17944.1 - 4.6e-13 49.2 1.0 8e-13 48.4 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EKG17944.1 - 1.7e-09 37.2 0.0 3.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1387 PF07139.6 EKG17945.1 - 0.32 10.5 9.6 0.02 14.5 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Aminotran_1_2 PF00155.16 EKG17946.1 - 1.6e-75 254.3 0.0 1.8e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKG17946.1 - 0.0024 17.0 0.0 0.0032 16.6 0.0 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase DHDPS PF00701.17 EKG17947.1 - 5.4e-47 159.7 0.0 6.9e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HTH_29 PF13551.1 EKG17947.1 - 0.099 12.7 0.6 13 5.9 0.0 3.2 2 1 0 3 3 3 0 Winged helix-turn helix HSP9_HSP12 PF04119.7 EKG17948.1 - 1.3e-21 76.4 10.5 8.2e-21 73.8 3.7 2.2 2 0 0 2 2 2 2 Heat shock protein 9/12 RFamide_26RFa PF11109.3 EKG17948.1 - 0.12 12.2 1.1 0.21 11.4 0.7 1.4 1 1 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 Fasciclin PF02469.17 EKG17949.1 - 7e-46 155.3 0.0 6.8e-28 97.2 0.0 3.0 2 1 0 2 2 2 2 Fasciclin domain DUF605 PF04652.11 EKG17949.1 - 0.86 8.9 4.7 1.2 8.4 3.2 1.1 1 0 0 1 1 1 0 Vta1 like Pyridoxal_deC PF00282.14 EKG17950.1 - 2.8e-60 203.7 0.0 4e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EKG17950.1 - 8.1e-06 24.8 0.0 1.4e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V zf-RING_2 PF13639.1 EKG17951.1 - 3.1e-11 42.9 4.7 8.2e-11 41.5 3.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EKG17951.1 - 1.5e-07 31.0 4.6 1.7e-07 30.8 0.4 2.6 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EKG17951.1 - 4.2e-07 29.5 3.0 4.2e-07 29.5 2.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EKG17951.1 - 1.6e-06 28.0 1.0 5.1e-06 26.5 0.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EKG17951.1 - 2.6e-06 27.3 5.9 3e-05 23.9 3.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG17951.1 - 2.6e-05 23.8 1.7 2.6e-05 23.8 1.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG17951.1 - 0.00012 21.6 4.7 0.00012 21.6 3.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EKG17951.1 - 0.0042 16.8 1.3 0.011 15.4 0.9 1.6 1 1 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EKG17951.1 - 0.016 14.7 4.6 0.031 13.8 0.3 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EKG17951.1 - 0.021 14.6 0.6 0.068 13.0 0.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EKG17951.1 - 0.084 12.4 4.0 0.2 11.2 2.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EKG17951.1 - 0.11 12.0 3.6 0.22 11.0 1.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EKG17951.1 - 0.29 11.0 6.1 0.27 11.1 2.3 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EKG17951.1 - 0.75 9.3 6.5 2.4 7.7 4.5 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger HET PF06985.6 EKG17952.1 - 2.3e-25 89.3 0.0 3.7e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UCR_hinge PF02320.11 EKG17953.1 - 1.7e-08 34.2 0.7 3.5e-08 33.2 0.5 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.4 EKG17953.1 - 0.15 12.1 1.0 0.23 11.5 0.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Macoilin PF09726.4 EKG17953.1 - 4.1 5.5 7.6 4.6 5.4 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Hydantoinase_B PF02538.9 EKG17954.1 - 4.6e-140 467.3 0.0 5.7e-140 467.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EKG17954.1 - 1.2e-84 283.9 0.0 3.6e-84 282.3 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EKG17954.1 - 2.4e-47 160.6 0.0 8.6e-46 155.6 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 EKG17955.1 - 3.4e-42 144.4 26.0 3.4e-42 144.4 18.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EKG17955.1 - 1.6e-05 24.4 4.1 1.6e-05 24.4 2.9 2.4 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Fungal_trans PF04082.13 EKG17956.1 - 9.3e-39 132.8 0.2 1.5e-38 132.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2238 PF09997.4 EKG17956.1 - 0.095 12.0 0.7 2.2 7.6 0.1 2.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2238) Zn_clus PF00172.13 EKG17959.1 - 3.3e-08 33.3 7.2 4.8e-08 32.7 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.16 EKG17961.1 - 5.6e-29 101.0 0.0 6.7e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.13 EKG17962.1 - 4.8e-21 74.8 0.3 1.4e-20 73.3 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Deltaretro_Tax PF05599.6 EKG17963.1 - 0.07 13.4 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Deltaretrovirus Tax protein COesterase PF00135.23 EKG17965.1 - 6.9e-58 196.6 0.0 1.2e-42 146.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family HATPase_c PF02518.21 EKG17966.1 - 1.8e-18 66.2 0.2 8.6e-18 64.0 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG17966.1 - 5.7e-12 45.6 0.1 1.6e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EKG17966.1 - 3.1e-10 39.9 0.7 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF3851 PF12962.2 EKG17966.1 - 0.0069 16.3 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3851) HATPase_c_3 PF13589.1 EKG17966.1 - 0.044 13.4 0.1 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1741 PF08427.5 EKG17967.1 - 3.8e-83 278.6 0.4 7.3e-83 277.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Rsa3 PF14615.1 EKG17967.1 - 0.013 14.8 0.0 0.032 13.5 0.0 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 AAA_18 PF13238.1 EKG17968.1 - 1.5e-06 28.5 0.0 1.1e-05 25.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG17968.1 - 3.5e-06 27.8 0.1 7.1e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG17968.1 - 0.00074 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.7 EKG17968.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EKG17968.1 - 0.0041 16.9 0.0 0.0094 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EKG17968.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EKG17968.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EKG17968.1 - 0.12 11.4 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Dabb PF07876.7 EKG17969.1 - 7.5e-25 87.2 0.0 8.4e-25 87.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fe-S_biosyn PF01521.15 EKG17970.1 - 1.2e-18 67.1 0.0 1.5e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 EKG17970.1 - 0.03 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) GspH PF12019.3 EKG17972.1 - 6.4 6.9 7.8 0.47 10.6 0.3 2.5 2 1 0 2 2 2 0 Type II transport protein GspH FAD_binding_7 PF03441.9 EKG17973.1 - 1.5e-52 178.4 0.1 2.1e-52 178.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EKG17973.1 - 6.6e-17 61.7 0.0 1.3e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Fungal_trans PF04082.13 EKG17974.1 - 5e-15 55.0 0.2 1.1e-14 54.0 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG17974.1 - 6e-06 26.0 9.8 1.4e-05 24.8 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_2 PF00328.17 EKG17975.1 - 3.9e-29 102.0 0.0 4.6e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ARPC4 PF05856.7 EKG17978.1 - 7.1e-76 253.3 4.5 7.8e-76 253.1 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 EKG17979.1 - 7.8e-56 189.1 0.0 9.5e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG17979.1 - 4.4e-17 62.4 0.5 4.8e-16 59.0 0.3 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EKG17979.1 - 6.8e-14 51.0 0.1 2.1e-13 49.4 0.1 1.9 1 0 0 1 1 1 1 Ubiquitin family Cystatin PF00031.16 EKG17979.1 - 0.083 13.0 0.1 0.5 10.5 0.0 2.3 2 1 0 2 2 2 0 Cystatin domain Rad21_Rec8 PF04824.11 EKG17980.1 - 2.6e-05 23.3 0.0 5.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Wbp11 PF09429.5 EKG17981.1 - 3.6e-20 71.7 12.8 3.6e-20 71.7 8.9 2.5 2 0 0 2 2 2 1 WW domain binding protein 11 POP1 PF06978.6 EKG17982.1 - 9.4e-63 211.2 9.5 2e-62 210.1 6.6 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EKG17982.1 - 2.2e-31 107.5 0.8 5.1e-31 106.3 0.5 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.16 EKG17982.1 - 4.4e-05 22.9 0.0 0.21 10.9 0.0 2.5 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain FAD_binding_2 PF00890.19 EKG17983.1 - 1.3e-48 165.8 0.1 1.9e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EKG17983.1 - 1.4e-43 147.8 0.1 1.9e-43 147.3 0.1 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Ribonuclease PF00545.15 EKG17984.1 - 1.5e-18 66.6 0.7 2.1e-18 66.1 0.5 1.3 1 0 0 1 1 1 1 ribonuclease UvdE PF03851.9 EKG17985.1 - 2.1e-113 377.9 0.0 2.7e-113 377.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE HLH PF00010.21 EKG17986.1 - 7.7e-13 47.9 0.8 1.2e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 EKG17986.1 - 0.16 12.2 2.9 0.29 11.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF1136 PF06582.7 EKG17986.1 - 2.1 8.0 7.1 8.8 6.1 1.1 3.1 3 0 0 3 3 3 0 Repeat of unknown function (DUF1136) Cloacin_immun PF03513.9 EKG17988.1 - 0.064 13.3 0.0 0.092 12.7 0.0 1.2 1 0 0 1 1 1 0 Cloacin immunity protein HET PF06985.6 EKG17990.1 - 3.2e-20 72.7 0.0 5.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 EKG17993.1 - 6.6e-25 87.1 0.2 2.7e-24 85.2 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EKG17993.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like DNA_pol_viral_C PF00336.13 EKG17994.1 - 0.067 12.4 0.0 0.13 11.4 0.0 1.4 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain Piwi PF02171.12 EKG17998.1 - 3.6e-08 32.7 0.0 4.6e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain MRP-S23 PF10484.4 EKG17998.1 - 0.022 14.6 0.7 0.038 13.8 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 Oxidored_FMN PF00724.15 EKG18001.1 - 4.5e-83 279.0 0.0 5.1e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DOCK-C2 PF14429.1 EKG18002.1 - 2.3e-29 102.3 0.0 4.2e-28 98.2 0.0 2.3 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EKG18002.1 - 7.6e-16 57.9 1.7 9.2e-16 57.6 0.1 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis SH3_1 PF00018.23 EKG18002.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.1 EKG18002.1 - 0.11 12.1 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.12 EKG18002.1 - 0.27 10.7 0.0 0.61 9.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Peptidase_M14 PF00246.19 EKG18003.1 - 5.4e-75 252.5 1.2 6.9e-75 252.2 0.9 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase GspH PF12019.3 EKG18003.1 - 0.025 14.7 0.3 0.067 13.3 0.2 1.7 1 0 0 1 1 1 0 Type II transport protein GspH Steroid_dh PF02544.11 EKG18004.1 - 9e-25 87.1 0.5 3.1e-24 85.4 0.2 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EKG18004.1 - 2.7e-05 23.6 0.2 3.7e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) An_peroxidase PF03098.10 EKG18005.1 - 4.6e-101 338.7 0.0 8.2e-99 331.3 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EKG18005.1 - 3.2e-09 35.8 0.0 1.1e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 Lactamase_B_2 PF12706.2 EKG18006.1 - 7.5e-22 77.8 0.2 1e-21 77.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG18006.1 - 2.9e-13 49.8 0.4 5.5e-13 48.9 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG18006.1 - 0.011 15.4 6.3 0.022 14.3 1.4 2.9 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily EHN PF06441.7 EKG18007.1 - 5.3e-11 42.4 0.1 1e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG18007.1 - 7.2e-11 42.3 0.1 1.9e-10 41.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG18007.1 - 6.4e-05 22.6 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pectinesterase PF01095.14 EKG18008.1 - 1.1e-154 513.4 44.5 7.5e-41 139.6 4.9 6.0 5 1 1 6 6 6 5 Pectinesterase NAD_binding_2 PF03446.10 EKG18009.1 - 1.3e-27 96.6 0.1 2.4e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EKG18009.1 - 7.9e-08 32.4 0.1 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EKG18009.1 - 0.0002 21.4 0.0 0.00054 20.0 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EKG18009.1 - 0.0075 16.6 0.0 0.039 14.3 0.0 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EKG18009.1 - 0.023 13.8 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EKG18009.1 - 0.14 11.4 0.7 0.53 9.6 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NACHT PF05729.7 EKG18010.1 - 9.5e-05 22.1 0.6 0.0011 18.6 0.4 2.0 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EKG18010.1 - 0.093 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF123 PF01986.11 EKG18010.1 - 0.28 11.3 1.6 0.32 11.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF123 Nudc_N PF14050.1 EKG18011.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. DUF2072 PF09845.4 EKG18012.1 - 0.16 11.8 1.2 0.21 11.5 0.1 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Intron_maturas2 PF01348.16 EKG18013.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II intron maturase Peptidase_S8 PF00082.17 EKG18014.1 - 4.5e-27 94.9 0.1 9.5e-27 93.8 0.1 1.6 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EKG18014.1 - 1.1e-11 45.0 0.1 2.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PigN PF04987.9 EKG18015.1 - 0.01 14.5 1.9 0.014 14.1 0.5 1.6 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) DUF2427 PF10348.4 EKG18015.1 - 0.56 9.8 4.6 0.44 10.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Pro_isomerase PF00160.16 EKG18017.1 - 1.3e-52 178.0 0.0 1.5e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lyase_1 PF00206.15 EKG18019.1 - 2.2e-113 378.5 0.0 3.4e-113 377.9 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EKG18019.1 - 7.5e-21 73.9 0.0 1.6e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus Luteo_PO PF04662.8 EKG18019.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Luteovirus P0 protein Pkinase PF00069.20 EKG18021.1 - 6.8e-56 189.2 0.0 3.9e-55 186.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG18021.1 - 2.1e-29 102.3 0.1 1.5e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EKG18021.1 - 8.3e-06 26.2 0.0 2.1e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EKG18021.1 - 7e-05 21.9 0.1 0.00068 18.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKG18021.1 - 0.00038 20.2 0.8 0.073 12.7 0.0 3.2 1 1 2 3 3 3 2 Phosphotransferase enzyme family HhH-GPD PF00730.20 EKG18022.1 - 3.1e-07 30.6 0.1 1.1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Abhydrolase_2 PF02230.11 EKG18023.1 - 8.6e-63 211.6 0.0 1e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EKG18023.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG18023.1 - 3.1e-07 30.5 0.0 0.0019 18.0 0.0 2.5 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG18023.1 - 5.3e-06 25.8 0.2 0.0033 16.6 0.0 2.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EKG18023.1 - 3.5e-05 23.4 0.0 0.25 10.9 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EKG18023.1 - 0.001 18.5 0.0 0.0079 15.6 0.0 2.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 EKG18023.1 - 0.0012 18.2 0.0 0.0027 17.0 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EKG18023.1 - 0.0093 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Lipase_3 PF01764.20 EKG18023.1 - 0.012 15.1 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 EKG18023.1 - 0.029 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Cutinase Esterase PF00756.15 EKG18023.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Putative esterase LIP PF03583.9 EKG18023.1 - 0.16 11.1 0.0 0.48 9.5 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase DUF829 PF05705.9 EKG18023.1 - 0.18 11.5 0.0 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) CinA PF02464.12 EKG18025.1 - 3.2e-33 114.3 0.4 3.7e-33 114.1 0.2 1.0 1 0 0 1 1 1 1 Competence-damaged protein Glyco_hydro_28 PF00295.12 EKG18026.1 - 1e-12 47.6 1.3 1.2e-12 47.4 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NAD_binding_6 PF08030.7 EKG18027.1 - 2.6e-18 66.4 0.0 2.3e-17 63.3 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EKG18027.1 - 4.5e-17 62.2 10.5 2e-16 60.2 6.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EKG18027.1 - 1.5e-13 50.5 0.0 3.2e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EKG18027.1 - 0.00012 22.5 0.0 0.51 10.9 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF162 PF02589.10 EKG18027.1 - 0.085 12.3 0.0 1.7 8.0 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised ACR, YkgG family COG1556 DUF3431 PF11913.3 EKG18028.1 - 5.1e-60 202.7 0.0 6.2e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) TRP PF06011.7 EKG18029.1 - 2.5e-97 326.2 26.3 4.3e-97 325.4 18.3 1.3 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EKG18029.1 - 6.1e-31 107.3 0.3 9.4e-31 106.7 0.2 1.3 1 0 0 1 1 1 1 ML-like domain TMEM237 PF15383.1 EKG18029.1 - 0.064 12.3 0.6 0.15 11.1 0.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 237 Corona_nucleoca PF00937.13 EKG18029.1 - 0.087 11.7 1.0 0.14 11.1 0.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SRP-alpha_N PF04086.8 EKG18030.1 - 7.5e-77 258.4 0.0 1e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EKG18030.1 - 1.5e-47 161.5 0.0 2.5e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EKG18030.1 - 1e-06 28.7 0.1 3.5e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EKG18030.1 - 1.4e-06 27.3 0.1 6.6e-06 25.1 0.0 1.9 1 1 1 2 2 2 1 ArgK protein CbiA PF01656.18 EKG18030.1 - 0.00025 20.4 0.1 0.00064 19.1 0.1 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EKG18030.1 - 0.0032 17.4 0.1 0.25 11.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EKG18030.1 - 0.0033 16.8 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EKG18030.1 - 0.0039 16.9 0.1 0.0091 15.7 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EKG18030.1 - 0.016 14.7 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKG18030.1 - 0.045 13.1 0.0 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 EKG18030.1 - 0.055 12.9 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKG18030.1 - 0.067 13.3 0.0 0.8 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EKG18030.1 - 0.078 12.9 0.1 0.23 11.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EKG18030.1 - 0.084 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EKG18030.1 - 0.18 11.7 0.3 0.84 9.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain YIF1 PF03878.10 EKG18031.1 - 7.3e-79 264.3 4.6 8.2e-79 264.1 3.2 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EKG18031.1 - 1.2e-05 24.8 4.8 1.2e-05 24.8 3.3 1.8 2 0 0 2 2 2 1 Yip1 domain Cyclin PF08613.6 EKG18032.1 - 8.5e-15 55.4 0.1 2.1e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EKG18032.1 - 0.0015 18.0 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Amidohydro_2 PF04909.9 EKG18033.1 - 1.7e-17 63.9 5.7 2e-17 63.6 4.0 1.1 1 0 0 1 1 1 1 Amidohydrolase SnoaL PF07366.7 EKG18034.1 - 0.00027 20.5 0.0 0.0005 19.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EKG18034.1 - 0.036 14.4 0.1 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain IER PF05760.7 EKG18034.1 - 8.5 6.2 13.7 5.9 6.7 5.0 2.4 2 0 0 2 2 2 0 Immediate early response protein (IER) PIP5K PF01504.13 EKG18035.1 - 3.1e-35 121.5 0.0 4.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DTW PF03942.10 EKG18035.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 DTW domain Sugar_tr PF00083.19 EKG18036.1 - 1.3e-77 261.3 18.7 1.5e-77 261.1 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG18036.1 - 2.5e-24 85.6 28.1 1.8e-17 63.1 1.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG18036.1 - 3.2e-05 22.5 3.1 3.2e-05 22.5 2.1 2.8 2 1 1 3 3 3 1 MFS/sugar transport protein DUF1228 PF06779.9 EKG18036.1 - 0.0012 18.8 9.8 0.054 13.5 0.5 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) Amidohydro_1 PF01979.15 EKG18037.1 - 2.5e-35 122.6 0.0 3.5e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EKG18037.1 - 1.2e-08 34.6 0.4 3.6e-05 23.1 0.0 3.0 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EKG18037.1 - 9.6e-06 25.8 0.1 0.094 12.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EKG18037.1 - 5.1e-05 23.0 0.0 0.00015 21.4 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EKG18037.1 - 6.5e-05 21.9 0.0 0.00064 18.7 0.0 2.0 1 1 1 2 2 2 1 Adenosine/AMP deaminase NAD_binding_2 PF03446.10 EKG18039.1 - 4.2e-07 29.9 0.0 6.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EKG18039.1 - 2.2e-06 27.9 0.1 3.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EKG18039.1 - 6.6e-05 22.1 0.0 8.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EKG18039.1 - 0.0033 17.1 0.1 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain Pyr_redox_2 PF07992.9 EKG18040.1 - 1.7e-12 47.6 2.1 2.3e-06 27.6 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG18040.1 - 4.3e-07 30.2 0.1 1.8e-06 28.2 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG18040.1 - 0.004 16.1 0.1 0.01 14.7 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG18040.1 - 0.0062 16.6 7.1 0.02 14.9 0.0 2.8 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG18040.1 - 0.076 11.9 0.0 6.9 5.4 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Med15_fungi PF05397.7 EKG18041.1 - 0.099 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 Ank_2 PF12796.2 EKG18041.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF2897 PF11446.3 EKG18041.1 - 0.19 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) AAA_22 PF13401.1 EKG18042.1 - 0.00029 20.9 0.0 0.00086 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKG18042.1 - 0.0013 17.6 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 EKG18042.1 - 0.0021 18.3 0.0 0.0063 16.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 EKG18042.1 - 0.0054 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EKG18042.1 - 0.0065 17.2 1.3 0.015 16.1 0.1 2.2 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EKG18042.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EKG18042.1 - 0.043 13.3 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 EKG18042.1 - 0.064 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EKG18042.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 EKG18042.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKG18042.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EKG18042.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG18042.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Med3 PF11593.3 EKG18045.1 - 2.6 7.2 7.4 2.9 7.0 5.1 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RGS PF00615.14 EKG18046.1 - 0.00016 21.7 0.0 0.041 13.9 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain EamA PF00892.15 EKG18047.1 - 9.9e-25 87.0 21.1 2.1e-15 56.8 3.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EKG18047.1 - 5.3e-07 29.8 7.1 5.3e-07 29.8 4.9 3.1 2 1 1 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 EKG18047.1 - 0.00088 18.2 8.3 0.0014 17.5 0.1 2.1 2 0 0 2 2 2 2 UAA transporter family ABC_tran PF00005.22 EKG18048.1 - 1.5e-48 164.5 0.0 2.2e-26 92.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKG18048.1 - 1.5e-17 64.5 1.6 6.6e-06 26.3 0.2 4.0 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EKG18048.1 - 3.1e-13 49.4 0.0 0.00056 19.1 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKG18048.1 - 4.9e-08 33.5 0.1 0.00072 19.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Chromo PF00385.19 EKG18048.1 - 6.7e-08 32.0 0.5 1.3e-07 31.1 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 EKG18048.1 - 2.4e-07 30.1 0.8 0.0084 15.6 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EKG18048.1 - 8.7e-07 29.7 0.2 0.066 14.0 0.0 3.1 2 1 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EKG18048.1 - 9.6e-07 28.1 0.1 0.072 12.1 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EKG18048.1 - 1e-06 28.0 0.0 0.0031 16.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EKG18048.1 - 2.3e-06 27.5 0.0 0.0092 15.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EKG18048.1 - 8.2e-06 26.3 0.0 0.018 15.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein HEAT_2 PF13646.1 EKG18048.1 - 1e-05 25.7 1.4 0.14 12.4 0.0 3.4 1 1 2 3 3 3 2 HEAT repeats NACHT PF05729.7 EKG18048.1 - 3.2e-05 23.6 0.3 0.19 11.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain SbcCD_C PF13558.1 EKG18048.1 - 5.5e-05 22.9 0.0 0.33 10.9 0.0 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EKG18048.1 - 8.2e-05 22.1 0.8 1 8.7 0.1 3.8 3 0 0 3 3 3 2 AAA-like domain DUF87 PF01935.12 EKG18048.1 - 9.7e-05 22.2 0.3 0.048 13.4 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EKG18048.1 - 9.9e-05 22.4 0.0 0.29 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EKG18048.1 - 0.00039 20.4 0.1 0.032 14.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 EKG18048.1 - 0.00092 18.9 0.0 0.91 9.2 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EKG18048.1 - 0.001 17.8 0.3 0.31 9.7 0.0 2.5 2 0 0 2 2 2 1 ArgK protein RNA_helicase PF00910.17 EKG18048.1 - 0.0027 17.8 0.1 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 EKG18048.1 - 0.0027 17.3 0.2 7.1 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EKG18048.1 - 0.0028 17.5 0.0 3.5 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EKG18048.1 - 0.0037 16.7 0.0 2.3 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EKG18048.1 - 0.004 16.6 0.3 0.95 8.9 0.1 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EKG18048.1 - 0.004 17.4 0.1 1.7 8.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain HEAT PF02985.17 EKG18048.1 - 0.0042 17.0 5.1 0.39 10.9 0.0 5.4 6 0 0 6 6 4 1 HEAT repeat DUF815 PF05673.8 EKG18048.1 - 0.006 15.5 0.5 0.13 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EKG18048.1 - 0.0061 16.3 0.0 0.26 11.0 0.0 2.8 2 1 0 2 2 2 1 Dynamin family AAA_14 PF13173.1 EKG18048.1 - 0.0067 16.3 0.0 8 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 EKG18048.1 - 0.0073 14.8 0.0 1.9 6.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EKG18048.1 - 0.008 15.6 0.0 0.55 9.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EKG18048.1 - 0.014 12.7 0.8 2 5.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CLASP_N PF12348.3 EKG18048.1 - 0.018 14.4 0.0 0.075 12.3 0.0 2.0 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.18 EKG18048.1 - 0.051 13.4 2.2 5 7.1 0.2 3.3 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat AAA PF00004.24 EKG18048.1 - 0.063 13.4 0.0 12 6.1 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG18048.1 - 0.078 12.9 0.6 5.5 6.9 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain cobW PF02492.14 EKG18048.1 - 0.081 12.3 0.1 14 5.0 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.20 EKG18048.1 - 0.091 12.2 0.0 14 5.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 EKG18048.1 - 0.091 11.7 0.0 3.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Septin DUF2752 PF10825.3 EKG18049.1 - 0.022 14.8 0.7 0.047 13.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) ICL PF00463.16 EKG18050.1 - 2.3e-197 656.3 0.1 2.7e-197 656.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EKG18050.1 - 2.5e-10 39.9 0.1 3.9e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase NPH3 PF03000.9 EKG18050.1 - 0.045 13.2 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 NPH3 family DUF2458 PF10454.4 EKG18050.1 - 0.093 12.6 0.1 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Arg_repressor_C PF02863.13 EKG18050.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Citrate_synt PF00285.16 EKG18051.1 - 3.4e-100 335.2 0.0 4e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Zn_clus PF00172.13 EKG18052.1 - 1.3e-07 31.3 6.3 1.9e-07 30.8 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.5 EKG18053.1 - 4.2e-57 192.9 0.2 5.8e-57 192.4 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC45 PF02724.9 EKG18053.1 - 0.094 10.7 4.0 0.12 10.3 2.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TYW3 PF02676.9 EKG18054.1 - 5.8e-61 205.1 0.0 7.1e-61 204.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Methyltransf_23 PF13489.1 EKG18055.1 - 2.8e-12 46.6 0.0 3.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18055.1 - 4.1e-10 40.2 0.0 6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18055.1 - 2.9e-09 37.2 0.0 7.8e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG18055.1 - 5.6e-08 32.1 0.0 7.5e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EKG18055.1 - 1.5e-07 31.1 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18055.1 - 4e-07 30.4 0.0 6.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG18055.1 - 0.00013 21.9 0.1 0.00024 21.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG18055.1 - 0.0002 21.6 0.0 0.00043 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG18055.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EKG18055.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EKG18055.1 - 0.15 10.8 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase NmrA PF05368.8 EKG18056.1 - 4.9e-16 58.6 0.0 6.2e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG18056.1 - 1.6e-11 44.5 0.6 2.4e-11 43.9 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG18056.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EKG18056.1 - 0.00049 19.1 0.1 0.00069 18.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EKG18056.1 - 0.00073 19.4 0.0 0.0012 18.7 0.0 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EKG18056.1 - 0.0025 18.1 0.0 0.0052 17.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EKG18056.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 EKG18056.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DLH PF01738.13 EKG18057.1 - 1.2e-14 54.1 0.0 1.4e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG18057.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF262 PF03235.9 EKG18059.1 - 5.2e-11 42.9 0.1 1.6e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function DUF262 Aldedh PF00171.17 EKG18060.1 - 1.6e-108 363.0 0.1 1.9e-108 362.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 EKG18061.1 - 2.3e-23 82.9 1.4 3e-23 82.5 0.9 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG18061.1 - 7.8e-08 32.1 0.5 1.3e-07 31.5 0.4 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG18061.1 - 8e-07 29.0 0.1 9.9e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EKG18061.1 - 0.0082 15.8 0.1 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gln-synt_C PF00120.19 EKG18062.1 - 1.5e-59 201.2 0.0 1.9e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Glyco_hydro_3 PF00933.16 EKG18063.1 - 3.1e-72 243.0 0.0 4e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG18063.1 - 3.5e-55 187.0 0.2 4.7e-54 183.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG18063.1 - 2.3e-13 49.8 0.2 5.3e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain Ferric_reduct PF01794.14 EKG18064.1 - 1.4e-17 63.9 12.9 3.2e-17 62.8 5.4 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EKG18064.1 - 3e-17 62.3 0.0 6.1e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EKG18064.1 - 6.1e-12 45.7 0.0 1.3e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EKG18064.1 - 0.0034 17.4 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Ctr PF04145.10 EKG18065.1 - 1.1e-31 109.8 0.4 1.3e-31 109.5 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family WH1 PF00568.18 EKG18067.1 - 3.3e-30 104.0 0.1 4.8e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EKG18067.1 - 2.2e-07 30.2 2.5 3.4e-07 29.6 1.1 1.9 2 0 0 2 2 2 1 WH2 motif DUF1183 PF06682.7 EKG18067.1 - 0.0021 17.7 3.0 0.0021 17.7 2.1 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1183) Gly-zipper_OmpA PF13436.1 EKG18067.1 - 0.036 13.7 2.7 4 7.1 1.3 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ERCC4 PF02732.10 EKG18069.1 - 6e-25 87.6 0.0 1.6e-24 86.2 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain Cellulase PF00150.13 EKG18070.1 - 2.2e-53 181.3 4.6 2.6e-53 181.0 3.2 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Asparaginase PF00710.15 EKG18071.1 - 4.8e-43 147.2 2.9 5.6e-43 146.9 2.0 1.1 1 0 0 1 1 1 1 Asparaginase Sel1 PF08238.7 EKG18072.1 - 1.7e-38 130.1 26.8 1.1e-06 29.0 0.3 8.3 7 0 0 7 7 7 7 Sel1 repeat TPR_5 PF12688.2 EKG18072.1 - 0.14 12.1 0.5 0.42 10.6 0.2 1.9 1 1 1 2 2 2 0 Tetratrico peptide repeat TPR_17 PF13431.1 EKG18072.1 - 0.16 12.2 3.1 4.9 7.6 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EKG18072.1 - 4 7.6 7.1 2.5 8.2 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat CBP4 PF07960.6 EKG18073.1 - 1.3e-37 128.2 0.2 1.4e-37 128.1 0.2 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.5 EKG18073.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Aldo_ket_red PF00248.16 EKG18074.1 - 1.7e-50 171.4 0.0 2e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family V-SNARE PF05008.10 EKG18075.1 - 0.004 17.2 0.3 0.0067 16.5 0.2 1.3 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus Cir_Bir_Yir PF06022.6 EKG18075.1 - 0.02 14.1 0.5 0.027 13.6 0.3 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir VP4_haemagglut PF00426.13 EKG18075.1 - 0.23 9.3 6.6 0.3 9.0 4.6 1.0 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) DUF973 PF06157.6 EKG18075.1 - 8.5 5.2 19.1 13 4.6 13.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) AAA PF00004.24 EKG18076.1 - 7.7e-16 58.4 0.0 1.3e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG18076.1 - 0.00048 20.9 0.0 0.0024 18.6 0.0 2.3 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 EKG18076.1 - 0.0014 18.9 0.0 0.0041 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKG18076.1 - 0.0018 18.0 0.1 0.0073 16.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG18076.1 - 0.0051 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKG18076.1 - 0.0087 15.9 0.0 0.024 14.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EKG18076.1 - 0.012 15.6 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EKG18076.1 - 0.035 14.0 0.1 0.49 10.3 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 EKG18076.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_3 PF07726.6 EKG18076.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PROL5-SMR PF15621.1 EKG18076.1 - 0.83 10.1 4.8 0.21 12.0 0.8 1.8 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family HATPase_c_2 PF13581.1 EKG18078.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MreB_Mbl PF06723.8 EKG18078.1 - 0.024 13.2 0.9 0.096 11.2 0.3 2.0 2 1 1 3 3 3 0 MreB/Mbl protein HSP70 PF00012.15 EKG18078.1 - 0.071 11.0 0.1 0.14 10.0 0.1 1.5 1 1 0 1 1 1 0 Hsp70 protein DUF1752 PF08550.5 EKG18079.1 - 0.065 12.8 0.4 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) DUF3632 PF12311.3 EKG18080.1 - 1e-08 35.2 0.1 1.3e-08 34.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) TMEM95 PF15203.1 EKG18080.1 - 0.097 12.0 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 TMEM95 family CLN3 PF02487.12 EKG18081.1 - 6.5e-21 74.5 1.4 8.5e-21 74.2 0.9 1.1 1 0 0 1 1 1 1 CLN3 protein Toxin_3 PF00537.13 EKG18082.1 - 0.42 10.5 10.5 0.8 9.6 7.3 1.4 1 0 0 1 1 1 0 Scorpion toxin-like domain CFEM PF05730.6 EKG18082.1 - 1 9.2 12.3 0.1 12.4 4.1 2.2 1 1 1 2 2 2 0 CFEM domain zf-C2H2 PF00096.21 EKG18085.1 - 3.3e-09 36.5 12.3 0.00023 21.3 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG18085.1 - 2.1e-07 30.9 9.4 6.1e-07 29.4 0.8 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG18085.1 - 2.6e-05 24.2 10.6 0.0056 16.9 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EKG18085.1 - 0.0074 16.4 3.4 0.023 14.8 1.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EKG18085.1 - 0.028 14.5 6.5 0.04 14.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EKG18085.1 - 0.068 13.1 1.6 2.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 EKG18085.1 - 2.1 8.2 7.8 7.4 6.4 0.6 2.3 1 1 1 2 2 2 0 BED zinc finger Pyrid_oxidase_2 PF13883.1 EKG18088.1 - 1.2e-44 152.0 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.27 EKG18089.1 - 1.1e-10 40.9 11.7 2.2e-05 24.1 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 EKG18089.1 - 0.0058 16.5 0.0 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 RWD domain UQ_con PF00179.21 EKG18090.1 - 1.3e-47 160.7 0.0 1.5e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG18090.1 - 0.0002 21.1 0.0 0.00027 20.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EKG18090.1 - 0.022 14.4 0.1 0.041 13.5 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EKG18090.1 - 0.083 12.7 0.1 0.093 12.6 0.0 1.4 1 1 0 1 1 1 0 RWD domain Chon_Sulph_att PF06566.6 EKG18091.1 - 0.17 11.4 1.6 0.23 11.0 1.1 1.1 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Ribosomal_L24e PF01246.15 EKG18092.1 - 1.6e-30 104.7 0.7 1.6e-30 104.7 0.5 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e zf-C2H2 PF00096.21 EKG18093.1 - 1.7e-11 43.7 11.7 5.9e-06 26.3 0.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG18093.1 - 1.6e-09 37.3 6.8 8e-05 22.7 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG18093.1 - 8e-09 35.3 9.6 1.7e-06 28.0 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EKG18093.1 - 0.00054 20.0 2.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EKG18093.1 - 0.0013 18.8 6.3 0.02 15.1 1.6 2.7 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 EKG18093.1 - 0.0046 16.8 4.0 0.22 11.4 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EKG18093.1 - 0.069 12.9 1.7 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger zf-CHY PF05495.7 EKG18093.1 - 0.092 12.9 1.3 0.17 12.0 0.9 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-met PF12874.2 EKG18093.1 - 0.16 12.2 3.2 0.36 11.1 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pkinase PF00069.20 EKG18094.1 - 3.7e-70 236.0 0.0 5.7e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG18094.1 - 1.1e-30 106.6 0.0 1.8e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKG18094.1 - 0.0017 17.4 0.0 0.004 16.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG18094.1 - 0.0051 16.5 0.6 0.057 13.1 0.0 2.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family Nup35_RRM PF05172.8 EKG18095.1 - 0.0047 16.6 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_15 PF00723.16 EKG18096.1 - 0.039 12.5 0.2 0.046 12.2 0.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 CreA PF05981.7 EKG18096.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 CreA protein Ribosomal_L14e PF01929.12 EKG18097.1 - 7.4e-27 93.5 0.3 1.2e-26 92.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EKG18097.1 - 9.3e-07 28.3 1.5 6.3e-06 25.6 0.2 2.4 2 0 0 2 2 2 1 KOW motif NAC PF01849.13 EKG18098.1 - 4.1e-26 90.2 0.1 6.7e-25 86.3 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EKG18098.1 - 0.0022 17.7 0.2 0.0041 16.9 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_Rpo13 PF12136.3 EKG18098.1 - 0.056 13.1 5.9 0.13 12.0 4.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain CDC45 PF02724.9 EKG18098.1 - 1.2 7.1 6.9 0.089 10.8 1.3 1.5 2 0 0 2 2 2 0 CDC45-like protein SpoIIIAH PF12685.2 EKG18098.1 - 2.1 7.8 12.8 0.27 10.6 4.7 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF4407 PF14362.1 EKG18098.1 - 4.1 6.2 10.3 0.95 8.3 4.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Mt_ATP-synt_D PF05873.7 EKG18099.1 - 7.8e-21 74.3 0.8 9.5e-21 74.1 0.6 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Syntaxin PF00804.20 EKG18099.1 - 0.03 14.4 1.4 0.048 13.8 1.0 1.3 1 0 0 1 1 1 0 Syntaxin V_ATPase_I PF01496.14 EKG18099.1 - 0.14 9.9 0.9 0.18 9.6 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2799 PF10973.3 EKG18099.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2799) IncA PF04156.9 EKG18099.1 - 0.52 9.8 3.1 2.3 7.7 2.2 1.8 1 1 1 2 2 2 0 IncA protein BLOC1_2 PF10046.4 EKG18099.1 - 0.56 10.3 2.7 0.71 10.0 0.7 1.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TrkH PF02386.11 EKG18100.1 - 7.6e-82 274.7 2.3 1.5e-76 257.2 0.7 2.1 2 0 0 2 2 2 2 Cation transport protein Ion_trans_2 PF07885.11 EKG18100.1 - 0.0068 16.1 4.3 0.0068 16.1 2.9 2.2 2 0 0 2 2 2 1 Ion channel Tom5 PF10642.4 EKG18101.1 - 4 7.1 5.0 3.6 7.3 0.3 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase WD40 PF00400.27 EKG18103.1 - 3e-15 55.4 3.8 0.0015 18.3 0.2 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat FGF-BP1 PF06473.7 EKG18103.1 - 1.6 8.2 6.9 0.42 10.1 2.6 1.5 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) COQ9 PF08511.6 EKG18105.1 - 7.8e-31 105.4 0.2 1.2e-30 104.8 0.1 1.3 1 0 0 1 1 1 1 COQ9 HTH_27 PF13463.1 EKG18106.1 - 0.051 13.8 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain HEAT_PBS PF03130.11 EKG18106.1 - 0.12 12.9 0.2 17 6.2 0.0 3.1 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat IL5 PF02025.10 EKG18106.1 - 0.12 12.3 0.3 0.73 9.8 0.1 2.2 2 0 0 2 2 2 0 Interleukin 5 MIT PF04212.13 EKG18107.1 - 3e-09 36.6 0.3 6.5e-09 35.5 0.2 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Patatin PF01734.17 EKG18108.1 - 2.4e-25 89.6 0.1 1.2e-24 87.3 0.1 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Acetyltransf_3 PF13302.1 EKG18109.1 - 2e-33 115.5 0.0 2.4e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG18109.1 - 0.00069 19.5 0.0 0.0016 18.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EKG18109.1 - 0.0031 17.4 0.0 0.054 13.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG18109.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain VMA21 PF09446.5 EKG18110.1 - 0.63 10.0 6.7 1.3 9.0 4.7 1.4 1 0 0 1 1 1 0 VMA21-like domain Tyrosinase PF00264.15 EKG18111.1 - 9.1e-25 88.1 0.2 1.2e-24 87.6 0.1 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Ribosomal_S6e PF01092.14 EKG18112.1 - 5.1e-64 213.6 0.2 5.1e-64 213.6 0.2 1.6 2 1 0 2 2 2 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 EKG18113.1 - 4.4e-44 148.9 0.3 1.1e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EKG18113.1 - 2.8e-43 147.8 1.4 6e-37 127.1 1.0 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EKG18113.1 - 2.7e-11 43.2 0.9 4.2e-10 39.4 0.4 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EKG18113.1 - 0.00019 20.7 0.3 0.00035 19.8 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Sugar_tr PF00083.19 EKG18114.1 - 4e-53 180.5 4.5 4.9e-53 180.3 3.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG18114.1 - 4.8e-06 25.5 16.3 0.0039 15.9 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-L-AF_C PF06964.7 EKG18115.1 - 1.4e-36 125.9 0.1 2.2e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus adh_short PF00106.20 EKG18116.1 - 7.5e-14 51.9 3.4 9.8e-14 51.6 0.4 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG18116.1 - 1.7e-07 31.0 0.4 3.2e-07 30.1 0.3 1.3 1 0 0 1 1 1 1 KR domain CRCB PF02537.10 EKG18116.1 - 0.087 12.7 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 CrcB-like protein Eno-Rase_NADH_b PF12242.3 EKG18116.1 - 0.089 12.5 0.3 8.1 6.3 0.1 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG18116.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ABC_membrane_2 PF06472.10 EKG18117.1 - 1.9e-109 365.1 2.8 1.9e-109 365.1 2.0 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EKG18117.1 - 1e-18 67.9 0.0 1.9e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKG18117.1 - 0.00016 21.7 0.0 0.00041 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EKG18117.1 - 0.0061 16.9 0.4 0.03 14.6 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EKG18117.1 - 0.023 14.1 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EKG18117.1 - 0.041 13.0 0.0 0.13 11.4 0.0 1.8 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EKG18117.1 - 0.048 13.6 0.1 0.15 12.0 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EKG18117.1 - 0.097 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynactin PF12455.3 EKG18118.1 - 1.5e-86 289.7 5.8 1.5e-86 289.7 4.0 3.4 4 0 0 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EKG18118.1 - 6e-22 77.1 0.4 1.1e-21 76.2 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain MHC_II_beta PF00969.14 EKG18118.1 - 0.14 12.1 2.2 2.9 7.9 0.1 3.3 2 0 0 2 2 2 0 Class II histocompatibility antigen, beta domain NUC173 PF08161.7 EKG18119.1 - 1.4e-73 246.4 0.1 1.4e-71 240.0 0.0 2.8 3 0 0 3 3 3 2 NUC173 domain COX6B PF02297.12 EKG18120.1 - 2.6e-20 72.1 3.5 3.1e-20 71.9 2.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EKG18120.1 - 0.0029 16.9 0.2 0.0054 16.1 0.2 1.5 1 0 0 1 1 1 1 APOBEC-like C-terminal domain B12D PF06522.6 EKG18121.1 - 4.2e-07 29.5 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 EKG18122.1 - 1.5e-17 62.9 0.0 2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG18122.1 - 9.3e-12 44.7 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG18122.1 - 8.9e-08 31.8 0.0 1.3e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKG18122.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SRA1 PF07304.6 EKG18123.1 - 1.2e-11 44.6 0.0 1.2e-11 44.6 0.0 2.6 3 1 1 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.27 EKG18123.1 - 1.9e-07 30.7 0.7 0.0012 18.6 0.4 2.6 1 1 1 2 2 2 2 WD domain, G-beta repeat Prp18 PF02840.10 EKG18123.1 - 0.018 14.8 2.4 0.061 13.1 0.2 2.6 2 1 1 3 3 3 0 Prp18 domain TPR_19 PF14559.1 EKG18123.1 - 0.041 14.2 2.3 2.9 8.2 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Calcipressin PF04847.7 EKG18124.1 - 1.1e-42 145.6 0.5 1.5e-42 145.2 0.4 1.1 1 0 0 1 1 1 1 Calcipressin ADH_zinc_N PF00107.21 EKG18125.1 - 3.8e-26 91.1 0.0 6.2e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG18125.1 - 6.9e-17 62.5 0.0 2e-16 61.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG18125.1 - 0.0033 17.1 0.1 0.0076 15.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Gla PF00594.15 EKG18125.1 - 0.016 14.8 0.3 0.03 14.0 0.2 1.4 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain AlaDh_PNT_C PF01262.16 EKG18125.1 - 0.016 14.7 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RNA_pol_A_bac PF01000.21 EKG18126.1 - 4.1e-32 110.6 0.0 5.7e-32 110.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EKG18126.1 - 0.001 18.1 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MFS_1 PF07690.11 EKG18127.1 - 1.9e-32 112.3 29.8 2.7e-32 111.8 20.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EKG18127.1 - 0.004 17.1 0.7 0.004 17.1 0.5 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1228) COesterase PF00135.23 EKG18128.1 - 8.9e-93 311.8 0.0 1.1e-92 311.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG18128.1 - 1.3e-06 28.1 0.2 1.1e-05 25.0 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_M20 PF01546.23 EKG18128.1 - 0.023 14.2 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_S9 PF00326.16 EKG18128.1 - 0.026 13.7 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4137 PF13593.1 EKG18129.1 - 6.9e-28 97.6 2.8 7.8e-28 97.4 2.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Mem_trans PF03547.13 EKG18129.1 - 0.043 12.1 1.4 0.12 10.6 1.0 1.7 1 1 0 1 1 1 0 Membrane transport protein Pyridoxal_deC PF00282.14 EKG18130.1 - 2.4e-19 69.0 0.0 3.6e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EKG18130.1 - 3.8e-07 29.1 0.0 8.2e-07 28.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EKG18130.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Sec6 PF06046.8 EKG18131.1 - 4.5e-159 530.1 2.5 4.5e-159 530.1 1.7 1.7 2 0 0 2 2 2 1 Exocyst complex component Sec6 NPV_P10 PF05531.7 EKG18131.1 - 0.02 15.1 1.8 5.8 7.2 0.1 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Nsp1_C PF05064.8 EKG18131.1 - 0.48 10.0 5.6 0.84 9.2 0.5 3.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region GrpE PF01025.14 EKG18132.1 - 2.7e-41 140.8 6.6 4.9e-41 140.0 4.6 1.4 1 1 0 1 1 1 1 GrpE Sox_N PF12444.3 EKG18132.1 - 0.022 15.8 1.0 1.8 9.7 0.0 2.5 2 0 0 2 2 2 0 Sox developmental protein N terminal Striatin PF08232.7 EKG18132.1 - 0.025 14.8 2.7 0.025 14.8 1.9 1.8 2 0 0 2 2 2 0 Striatin family T4SS-DNA_transf PF02534.9 EKG18132.1 - 0.072 11.6 0.2 0.098 11.2 0.1 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF4652 PF15525.1 EKG18132.1 - 0.18 11.1 6.9 0.29 10.5 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) DUF3306 PF11748.3 EKG18132.1 - 0.25 12.0 6.6 0.088 13.4 2.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Bap31 PF05529.7 EKG18132.1 - 0.85 9.0 11.5 0.071 12.5 4.5 1.7 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like IncA PF04156.9 EKG18132.1 - 5.4 6.5 7.9 6.8 6.2 5.2 1.5 1 1 0 1 1 1 0 IncA protein PrpF PF04303.8 EKG18133.1 - 2.3e-112 375.4 0.9 2.7e-112 375.2 0.7 1.0 1 0 0 1 1 1 1 PrpF protein Terpene_synth_C PF03936.11 EKG18134.1 - 3.8e-06 26.3 0.2 1.9e-05 24.0 0.0 2.1 3 0 0 3 3 3 1 Terpene synthase family, metal binding domain Laminin_EGF PF00053.19 EKG18135.1 - 0.87 9.5 7.7 0.39 10.6 3.1 1.9 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) p450 PF00067.17 EKG18136.1 - 1.6e-21 76.4 0.0 2.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EKG18139.1 - 0.0032 16.3 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dehydratase_hem PF13816.1 EKG18142.1 - 3.6e-97 325.1 0.0 4.2e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EKG18142.1 - 1.1e-05 25.5 0.0 0.00012 22.1 0.0 2.4 2 1 0 3 3 3 1 Domain of unknown function (DUF4188) MerB PF03243.10 EKG18142.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Alkylmercury lyase CTNNBL PF08216.6 EKG18143.1 - 1.9e-35 120.6 0.1 1.9e-35 120.6 0.1 3.1 3 1 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EKG18143.1 - 0.0022 17.7 0.0 4.3 7.3 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Mo25 PF08569.6 EKG18143.1 - 0.024 13.6 0.9 0.053 12.5 0.3 1.8 2 1 0 2 2 2 0 Mo25-like HEAT_2 PF13646.1 EKG18143.1 - 0.058 13.6 5.6 1 9.6 0.2 3.7 2 2 0 3 3 3 0 HEAT repeats F-box-like PF12937.2 EKG18144.1 - 1.9e-06 27.4 0.2 7.6e-06 25.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKG18144.1 - 5.8e-05 22.6 0.2 0.00021 20.8 0.0 2.1 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EKG18144.1 - 0.013 15.2 1.6 21 4.9 0.1 4.8 4 2 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EKG18144.1 - 0.025 14.5 1.6 36 4.8 0.0 5.3 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 EKG18144.1 - 0.061 13.5 0.4 61 4.4 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat tRNA-synt_2 PF00152.15 EKG18145.1 - 2.9e-74 249.8 0.0 3.8e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKG18145.1 - 4.9e-13 48.7 0.0 9.7e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EKG18145.1 - 9.4e-06 24.9 0.1 0.0029 16.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EKG18145.1 - 0.01 15.4 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) RuvB_C PF05491.8 EKG18145.1 - 0.032 13.8 0.1 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Holliday junction DNA helicase ruvB C-terminus DUF4197 PF13852.1 EKG18145.1 - 0.062 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) zf-Tim10_DDP PF02953.10 EKG18146.1 - 2.1e-21 74.9 3.6 4.5e-18 64.2 0.9 2.1 1 1 1 2 2 2 2 Tim10/DDP family zinc finger AlaDh_PNT_N PF05222.10 EKG18147.1 - 6.3e-21 74.8 0.0 9.3e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EKG18147.1 - 0.0028 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lipase_3 PF01764.20 EKG18148.1 - 8.2e-37 125.9 0.0 1.3e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EKG18148.1 - 0.0064 15.8 0.7 0.051 12.9 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.17 EKG18148.1 - 0.023 14.4 0.3 0.038 13.7 0.2 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 EKG18148.1 - 0.024 14.5 1.1 0.085 12.7 0.2 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.15 EKG18148.1 - 0.035 13.5 0.1 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative esterase CybS PF05328.7 EKG18149.1 - 7.7e-49 164.7 0.0 9.7e-49 164.4 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EKG18149.1 - 0.17 11.7 2.8 3.1 7.6 1.9 2.2 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M16_C PF05193.16 EKG18150.1 - 2.6e-37 128.2 0.0 5.4e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EKG18150.1 - 5.6e-23 81.3 0.1 1.8e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) IATP PF04568.7 EKG18151.1 - 9.3e-23 80.1 0.7 1.1e-22 79.9 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP AAA_23 PF13476.1 EKG18151.1 - 0.0049 17.2 0.7 0.0054 17.0 0.5 1.1 1 0 0 1 1 1 1 AAA domain NinG PF05766.7 EKG18151.1 - 0.008 15.9 0.5 0.0094 15.7 0.3 1.1 1 0 0 1 1 1 1 Bacteriophage Lambda NinG protein DUF489 PF04356.7 EKG18151.1 - 0.011 15.3 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) COG5 PF10392.4 EKG18151.1 - 0.069 13.1 0.5 0.096 12.6 0.3 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3450 PF11932.3 EKG18151.1 - 0.071 12.3 0.1 0.071 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 EKG18151.1 - 0.094 11.6 0.5 0.094 11.6 0.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3347 PF11827.3 EKG18151.1 - 0.1 12.5 0.2 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) 14-3-3 PF00244.15 EKG18152.1 - 2.3e-117 390.1 6.6 2.7e-117 389.9 4.6 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EKG18152.1 - 0.019 14.4 2.1 1.3 8.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF2205 PF10224.4 EKG18154.1 - 1.6e-29 101.2 0.5 2.6e-29 100.5 0.4 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Nsp1_C PF05064.8 EKG18157.1 - 2.9e-40 136.5 4.5 2.9e-40 136.5 3.1 2.0 2 1 0 2 2 2 1 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 EKG18157.1 - 0.00048 19.9 6.2 0.00048 19.9 4.3 1.7 1 1 1 2 2 2 1 Tropomyosin like Baculo_PEP_C PF04513.7 EKG18157.1 - 0.0012 18.7 1.9 0.005 16.6 1.3 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Synaptonemal_3 PF15191.1 EKG18157.1 - 0.017 14.8 0.1 0.05 13.3 0.1 1.8 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Syntaxin PF00804.20 EKG18157.1 - 0.026 14.6 5.0 0.85 9.8 3.5 2.4 1 1 0 1 1 1 0 Syntaxin EzrA PF06160.7 EKG18157.1 - 0.026 12.7 12.0 0.099 10.8 0.4 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA APG6 PF04111.7 EKG18157.1 - 0.053 12.5 9.9 0.011 14.7 4.1 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 APG17 PF04108.7 EKG18157.1 - 0.088 11.5 5.1 0.15 10.8 3.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 MscS_porin PF12795.2 EKG18157.1 - 0.11 11.7 13.5 0.11 11.8 1.7 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF342 PF03961.8 EKG18157.1 - 0.13 10.6 6.5 0.28 9.5 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 EKG18157.1 - 0.15 10.4 10.1 0.034 12.6 0.6 1.9 1 1 1 2 2 2 0 AAA domain LOH1CR12 PF10158.4 EKG18157.1 - 0.15 11.8 2.1 4.9 6.9 1.1 2.4 1 1 1 2 2 2 0 Tumour suppressor protein Tropomyosin PF00261.15 EKG18157.1 - 0.16 11.0 7.8 0.13 11.3 4.1 1.6 1 1 0 1 1 1 0 Tropomyosin DUF4559 PF15112.1 EKG18157.1 - 0.17 11.0 6.4 0.23 10.5 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Laminin_I PF06008.9 EKG18157.1 - 0.17 11.1 12.0 0.65 9.2 1.4 2.2 1 1 1 2 2 2 0 Laminin Domain I DUF972 PF06156.8 EKG18157.1 - 0.29 11.4 7.6 0.43 10.9 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 EKG18157.1 - 0.42 10.3 10.1 0.46 10.2 1.0 2.8 1 1 2 3 3 3 0 Laminin Domain II GAS PF13851.1 EKG18157.1 - 0.44 9.7 12.6 0.58 9.3 1.4 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nup54 PF13874.1 EKG18157.1 - 0.47 10.1 4.2 0.2 11.2 0.4 2.1 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Myosin_tail_1 PF01576.14 EKG18157.1 - 0.48 8.0 13.8 0.9 7.1 9.5 1.3 1 1 0 1 1 1 0 Myosin tail Syntaxin_2 PF14523.1 EKG18157.1 - 0.85 9.6 7.8 8.3 6.5 0.3 2.7 2 2 0 2 2 2 0 Syntaxin-like protein Spc7 PF08317.6 EKG18157.1 - 1.6 7.2 12.3 1.6 7.2 0.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.1 EKG18157.1 - 1.7 8.6 12.9 2.4 8.0 5.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 EKG18157.1 - 1.9 8.9 9.9 4.9 7.6 0.5 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF4164 PF13747.1 EKG18157.1 - 2.5 8.2 7.5 1.7 8.8 1.3 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4164) ATG16 PF08614.6 EKG18157.1 - 3.7 7.3 15.0 7.1 6.3 5.9 2.8 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.7 EKG18157.1 - 7.7 6.8 6.5 2.2e+02 2.1 3.2 3.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein HAMP PF00672.20 EKG18159.1 - 3.5e-44 148.8 22.2 2.3e-09 37.3 0.6 7.1 6 0 0 6 6 6 6 HAMP domain Response_reg PF00072.19 EKG18159.1 - 7.6e-30 103.2 0.5 2.2e-26 92.0 0.3 3.1 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 EKG18159.1 - 9.7e-29 99.3 0.1 3.1e-28 97.7 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EKG18159.1 - 1.3e-17 63.5 0.6 1.3e-17 63.5 0.4 4.7 6 0 0 6 6 5 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EKG18159.1 - 1.4e-05 23.8 11.0 0.091 11.2 0.1 3.3 1 1 3 4 4 4 4 AAA domain DUF883 PF05957.8 EKG18159.1 - 0.0012 19.1 19.3 5.6 7.4 0.4 7.0 5 3 2 7 7 7 2 Bacterial protein of unknown function (DUF883) NAAA-beta PF15508.1 EKG18159.1 - 0.022 15.0 5.9 7.6 6.9 0.1 6.1 4 3 2 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Las1 PF04031.8 EKG18159.1 - 0.072 12.7 2.8 4.3 6.9 0.1 4.0 4 0 0 4 4 4 0 Las1-like DUF2365 PF10157.4 EKG18159.1 - 0.12 12.2 12.2 12 5.7 0.1 6.5 5 2 1 6 6 6 0 Uncharacterized conserved protein (DUF2365) Pox_A_type_inc PF04508.7 EKG18159.1 - 0.21 11.4 6.6 0.51 10.2 0.2 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF948 PF06103.6 EKG18159.1 - 0.68 9.8 33.4 12 5.8 0.0 9.3 8 2 1 9 9 9 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EKG18159.1 - 0.98 8.9 13.1 0.4 10.2 2.7 3.9 4 0 0 4 4 4 0 IncA protein CCDC-167 PF15188.1 EKG18159.1 - 1.1 9.2 13.2 11 6.0 0.0 6.5 6 1 0 6 6 6 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.6 EKG18159.1 - 1.2 7.6 20.9 0.15 10.7 1.2 5.1 4 2 1 5 5 5 0 Spc7 kinetochore protein AcylCoA_dehyd_C PF12186.3 EKG18159.1 - 2.6 7.9 10.1 14 5.5 0.0 5.2 7 0 0 7 7 5 0 Acyl-CoA dehydrogenase C terminal DUF4477 PF14780.1 EKG18159.1 - 4.5 6.5 6.5 18 4.6 0.0 4.1 6 0 0 6 6 6 0 Domain of unknown function (DUF4477) WXG100 PF06013.7 EKG18159.1 - 5.4 7.0 29.6 0.58 10.1 0.2 7.7 7 2 1 8 8 7 0 Proteins of 100 residues with WXG SNF2_N PF00176.18 EKG18160.1 - 1.2e-71 240.9 0.2 1.7e-71 240.4 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG18160.1 - 7.5e-13 48.1 0.0 1.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EKG18160.1 - 2.4e-09 37.0 6.6 4.4e-09 36.2 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG18160.1 - 6.5e-09 35.3 3.1 1.2e-08 34.4 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG18160.1 - 2.2e-08 33.6 5.8 3.9e-08 32.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG18160.1 - 1.2e-07 31.3 5.6 2.2e-07 30.5 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EKG18160.1 - 2.2e-07 30.6 8.3 4.3e-07 29.7 5.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EKG18160.1 - 4.4e-06 26.3 4.9 8e-06 25.4 3.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EKG18160.1 - 9.1e-06 25.2 0.0 6e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 EKG18160.1 - 7.8e-05 22.3 2.9 0.00016 21.2 2.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EKG18160.1 - 0.00085 18.7 2.6 0.0017 17.8 1.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_4 PF14570.1 EKG18160.1 - 0.00099 18.6 6.9 0.0035 16.8 5.0 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain SPT6_acidic PF14632.1 EKG18160.1 - 0.0036 17.4 10.1 0.0073 16.4 7.0 1.5 1 0 0 1 1 1 1 Acidic N-terminal SPT6 ADIP PF11559.3 EKG18161.1 - 1.3e-07 31.6 0.7 1.3e-07 31.6 0.5 2.6 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Dus PF01207.12 EKG18162.1 - 2.5e-37 128.3 0.0 7.2e-27 94.0 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) SIS_2 PF13580.1 EKG18162.1 - 0.00013 21.6 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 SIS domain zf-CCCH PF00642.19 EKG18162.1 - 0.033 13.8 2.9 0.37 10.5 0.2 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 EKG18163.1 - 0.00055 20.0 12.8 0.45 10.9 0.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG18163.1 - 0.0033 17.5 2.5 0.13 12.3 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EKG18163.1 - 0.0064 16.7 11.7 0.019 15.2 0.5 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EKG18163.1 - 0.028 14.7 16.9 0.049 13.9 0.8 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type SprT-like PF10263.4 EKG18163.1 - 0.039 13.6 0.5 0.074 12.7 0.3 1.4 1 0 0 1 1 1 0 SprT-like family zf-C2H2_6 PF13912.1 EKG18163.1 - 9.5 6.2 7.3 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_23 PF13489.1 EKG18165.1 - 6.1e-12 45.5 0.1 7.9e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18165.1 - 0.00012 22.4 0.0 0.00032 21.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18165.1 - 0.00043 20.7 0.0 0.00095 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18165.1 - 0.0031 18.0 0.0 0.0059 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.13 EKG18166.1 - 1.3e-19 70.1 0.0 2.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG18166.1 - 2.1e-07 30.6 10.5 3.9e-07 29.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF898 PF05987.8 EKG18166.1 - 0.09 11.6 0.1 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) AHS1 PF02682.11 EKG18166.1 - 0.12 11.8 0.0 0.66 9.3 0.0 2.2 3 0 0 3 3 3 0 Allophanate hydrolase subunit 1 WD40 PF00400.27 EKG18167.1 - 4.2e-29 99.3 12.2 2e-09 36.9 0.0 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 EKG18167.1 - 1.6e-07 31.2 0.3 0.012 15.3 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EKG18167.1 - 0.035 13.8 0.2 0.035 13.8 0.2 3.7 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term PPP4R2 PF09184.6 EKG18168.1 - 3.8e-10 39.8 0.1 2.4e-08 33.8 0.0 2.5 2 1 0 2 2 2 2 PPP4R2 LisH PF08513.6 EKG18169.1 - 0.19 11.5 0.3 0.39 10.5 0.2 1.5 1 0 0 1 1 1 0 LisH TRAPP PF04051.11 EKG18170.1 - 2.9e-38 130.7 0.0 3.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EKG18171.1 - 8.8e-59 193.4 5.0 1.1e-08 34.5 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EKG18171.1 - 0.00013 21.7 0.0 0.087 12.5 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EKG18171.1 - 0.0012 17.7 0.5 0.32 9.7 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 EKG18171.1 - 0.0052 16.2 0.1 0.73 9.2 0.0 2.7 2 1 1 3 3 2 2 PQQ-like domain Nup160 PF11715.3 EKG18171.1 - 0.0082 14.3 0.6 0.28 9.2 0.0 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 MFS_1 PF07690.11 EKG18173.1 - 4.8e-07 28.8 21.6 2e-06 26.7 15.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18173.1 - 0.0023 16.5 12.6 0.0031 16.1 8.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter APH PF01636.18 EKG18175.1 - 2.7e-07 30.5 0.4 4.8e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RGS PF00615.14 EKG18176.1 - 0.057 13.5 0.1 0.09 12.8 0.0 1.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain F-box-like_2 PF13013.1 EKG18176.1 - 0.062 13.0 0.0 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 F-box-like domain Fumerase PF05681.9 EKG18176.1 - 0.071 12.1 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) HLH PF00010.21 EKG18179.1 - 4.1e-12 45.6 0.0 1.1e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_2 PF07716.10 EKG18179.1 - 0.039 13.7 1.5 0.039 13.7 1.0 2.7 3 0 0 3 3 3 0 Basic region leucine zipper CytochromB561_N PF09786.4 EKG18179.1 - 1.9 6.8 16.4 0.65 8.3 4.7 2.3 2 0 0 2 2 2 0 Cytochrome B561, N terminal HSP20 PF00011.16 EKG18180.1 - 1.1e-09 38.1 0.0 9.9e-09 34.9 0.0 2.2 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Pheromone PF08015.6 EKG18180.1 - 2.4 9.0 10.8 0.1 13.4 0.6 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone UDG PF03167.14 EKG18181.1 - 3e-18 65.7 0.0 4.9e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pectate_lyase PF03211.8 EKG18183.1 - 1.1e-62 211.2 8.3 1.3e-62 210.9 5.8 1.0 1 0 0 1 1 1 1 Pectate lyase GWT1 PF06423.7 EKG18185.1 - 1.6e-41 141.5 0.5 3.7e-41 140.4 0.3 1.6 1 1 0 1 1 1 1 GWT1 CLTH PF10607.4 EKG18188.1 - 1.5e-26 92.8 0.2 8.1e-26 90.4 0.0 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EKG18188.1 - 2.2e-18 65.6 0.7 5.4e-18 64.4 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EKG18188.1 - 0.00017 21.3 0.3 0.0003 20.5 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.7 EKG18188.1 - 0.00058 19.1 0.0 0.00058 19.1 0.0 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 EKG18188.1 - 0.0016 18.4 0.6 0.0028 17.6 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG18188.1 - 0.0016 18.0 0.2 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG18188.1 - 0.018 14.7 0.2 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG18188.1 - 0.042 13.5 0.5 0.08 12.6 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PG_binding_1 PF01471.13 EKG18189.1 - 0.0027 17.6 0.1 1.5 8.8 0.1 3.6 3 0 0 3 3 3 2 Putative peptidoglycan binding domain MIP PF00230.15 EKG18190.1 - 4.9e-49 166.8 13.5 6.4e-49 166.4 9.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein zf-C2H2 PF00096.21 EKG18192.1 - 5.8e-07 29.4 56.2 0.14 12.5 1.4 8.7 7 1 1 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG18192.1 - 0.0052 17.0 52.1 0.9 10.0 3.9 7.9 6 2 2 8 8 8 5 C2H2-type zinc finger zf-trcl PF13451.1 EKG18192.1 - 0.05 13.2 0.8 0.05 13.2 0.5 5.2 5 1 0 5 5 5 0 Probable zinc-binding domain zf-H2C2_2 PF13465.1 EKG18192.1 - 0.18 12.1 0.2 0.18 12.1 0.1 7.0 7 0 0 7 7 7 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EKG18192.1 - 4.9 7.4 36.9 0.95 9.6 1.2 6.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EKG18192.1 - 6.9 6.7 33.4 2.2 8.3 0.3 5.2 4 1 1 5 5 5 0 Zinc ribbon domain DUF500 PF04366.7 EKG18193.1 - 2.3e-44 149.8 0.1 3.8e-44 149.1 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) AvrE PF11725.3 EKG18193.1 - 1.5 5.7 15.7 2.1 5.2 10.9 1.1 1 0 0 1 1 1 0 Pathogenicity factor CAF-1_p150 PF11600.3 EKG18195.1 - 0.036 13.4 16.8 0.083 12.2 11.6 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_BLRF2 PF05812.7 EKG18195.1 - 0.17 11.6 6.8 0.57 9.9 1.3 2.6 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein GAGA_bind PF06217.7 EKG18195.1 - 0.21 11.4 5.3 0.32 10.9 3.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 EKG18195.1 - 0.46 9.1 11.7 0.091 11.4 5.7 1.5 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Mei5 PF10376.4 EKG18195.1 - 3.7 7.0 18.4 1.7e+03 -1.7 12.7 2.9 1 1 0 1 1 1 0 Double-strand recombination repair protein AA_permease_2 PF13520.1 EKG18196.1 - 6.9e-41 140.1 47.1 8.6e-41 139.8 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG18196.1 - 8.2e-22 77.1 41.0 1.1e-21 76.7 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4094 PF13334.1 EKG18196.1 - 9 6.7 9.8 8.7 6.8 1.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Glyco_transf_28 PF03033.15 EKG18197.1 - 1.9e-21 76.3 0.0 6.3e-21 74.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EKG18197.1 - 2.7e-06 26.2 0.0 4.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EKG18197.1 - 0.0037 16.9 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EKG18197.1 - 0.0091 16.1 0.0 0.033 14.3 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain Pox_G5 PF04599.7 EKG18197.1 - 0.2 10.2 0.1 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G5 protein PcfK PF14058.1 EKG18197.1 - 2.5 8.2 5.6 0.44 10.6 0.0 2.5 2 0 0 2 2 2 0 PcfK-like protein UQ_con PF00179.21 EKG18198.1 - 2.1e-47 160.0 0.0 2.5e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EKG18198.1 - 0.00046 20.0 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EKG18198.1 - 0.0011 18.6 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 EKG18198.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B BRE PF06113.7 EKG18198.1 - 0.13 11.2 0.1 0.32 9.9 0.1 1.6 1 1 1 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) Cutinase PF01083.17 EKG18199.1 - 9.9e-38 129.6 1.1 1.2e-37 129.3 0.8 1.1 1 0 0 1 1 1 1 Cutinase Lipase PF00151.14 EKG18199.1 - 0.0096 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipase PE-PPE PF08237.6 EKG18199.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF3530 PF12048.3 EKG18199.1 - 0.047 12.6 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) HLH PF00010.21 EKG18201.1 - 1.5e-07 30.9 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3732 PF12532.3 EKG18201.1 - 0.026 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) Membr_traf_MHD PF10540.4 EKG18203.1 - 1.5e-27 96.0 0.4 4.7e-27 94.4 0.3 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EKG18203.1 - 2.6e-15 56.0 0.0 5.4e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Cass2 PF14526.1 EKG18203.1 - 0.024 14.6 0.0 0.099 12.6 0.0 2.0 1 0 0 1 1 1 0 Integron-associated effector binding protein Cache_2 PF08269.6 EKG18204.1 - 0.11 12.4 0.3 0.53 10.2 0.0 2.4 3 0 0 3 3 3 0 Cache domain Ribosomal_L18ae PF01775.12 EKG18205.1 - 1.4e-27 96.0 0.7 2.3e-27 95.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain RVT_3 PF13456.1 EKG18205.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like DUF3531 PF12049.3 EKG18205.1 - 0.092 12.4 0.5 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3531) PCI PF01399.22 EKG18206.1 - 1.3e-10 41.4 0.0 3.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_11 PF13414.1 EKG18206.1 - 0.032 13.8 0.1 0.086 12.4 0.0 1.7 1 0 0 1 1 1 0 TPR repeat IncFII_repA PF02387.10 EKG18206.1 - 0.066 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 IncFII RepA protein family TPR_2 PF07719.12 EKG18206.1 - 0.41 10.6 2.6 0.82 9.7 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat A_deaminase PF00962.17 EKG18208.1 - 4.6e-46 157.2 0.0 1.1e-45 156.0 0.0 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase IRF PF00605.12 EKG18208.1 - 0.024 14.3 0.2 0.066 12.9 0.1 1.7 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor ATG2_CAD PF13329.1 EKG18209.1 - 2.7e-40 137.4 0.6 8.7e-40 135.8 0.0 2.3 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EKG18209.1 - 1.9e-22 79.2 0.2 7.5e-22 77.3 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain Fmp27 PF10344.4 EKG18209.1 - 0.94 7.0 7.1 0.039 11.6 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial protein from FMP27 SBF PF01758.11 EKG18210.1 - 7.1e-48 162.4 10.1 7.1e-48 162.4 7.0 1.8 1 1 0 2 2 2 1 Sodium Bile acid symporter family FAD-oxidase_C PF02913.14 EKG18211.1 - 3.1e-55 187.1 0.1 5.4e-55 186.4 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EKG18211.1 - 1.7e-39 134.4 0.0 3.3e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF1168 PF06658.7 EKG18212.1 - 0.026 14.0 12.3 0.098 12.1 6.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Draxin PF15550.1 EKG18212.1 - 3.6 7.1 13.6 0.19 11.3 5.4 1.8 2 0 0 2 2 2 0 Draxin Ran_BP1 PF00638.13 EKG18214.1 - 6.4e-07 29.4 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EKG18214.1 - 0.0046 17.1 39.2 0.0046 17.1 27.2 13.1 2 2 8 10 10 10 3 Nucleoporin FG repeat region WH1 PF00568.18 EKG18214.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 WH1 domain PCI PF01399.22 EKG18216.1 - 8.2e-06 26.0 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 PCI domain DinB_2 PF12867.2 EKG18216.1 - 0.084 13.2 2.6 0.3 11.4 1.8 2.0 1 1 0 1 1 1 0 DinB superfamily E1-E2_ATPase PF00122.15 EKG18217.1 - 1.1e-53 181.5 1.2 2.5e-53 180.4 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKG18217.1 - 1.9e-42 146.1 4.0 2.3e-42 145.8 1.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EKG18217.1 - 2.8e-34 117.0 0.1 4.5e-10 39.5 0.0 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 EKG18217.1 - 1e-11 45.4 0.0 3.7e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG18217.1 - 0.001 18.7 0.2 0.044 13.3 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2984 PF11203.3 EKG18217.1 - 0.0014 18.7 6.7 1.2 9.2 0.9 4.1 2 2 0 2 2 2 2 Protein of unknown function (DUF2984) Peptidase_C25 PF01364.13 EKG18217.1 - 0.12 11.3 1.1 0.2 10.5 0.1 1.9 2 0 0 2 2 2 0 Peptidase family C25 ERG4_ERG24 PF01222.12 EKG18218.1 - 3.2e-09 35.8 0.0 4.3e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ERG4_ERG24 PF01222.12 EKG18219.1 - 2.7e-82 276.6 0.7 3e-82 276.4 0.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EKG18219.1 - 1.1e-05 24.8 1.2 2.3e-05 23.7 0.2 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) PhyH PF05721.8 EKG18220.1 - 7.5e-08 32.6 0.0 1e-07 32.2 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Tyrosinase PF00264.15 EKG18221.1 - 1e-51 176.2 2.5 1e-51 176.2 1.7 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase MFS_1 PF07690.11 EKG18222.1 - 1.4e-37 129.2 34.9 6.2e-35 120.5 8.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18222.1 - 9e-13 47.5 2.2 9e-13 47.5 1.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EKG18222.1 - 2e-12 46.2 0.3 3.7e-06 25.6 1.0 3.8 1 1 3 4 4 4 3 MFS/sugar transport protein Folate_carrier PF01770.13 EKG18222.1 - 0.0021 16.6 0.1 0.0039 15.7 0.1 1.4 1 0 0 1 1 1 1 Reduced folate carrier MFS_1_like PF12832.2 EKG18222.1 - 0.0028 17.4 3.1 0.03 14.1 0.0 2.8 2 0 0 2 2 2 1 MFS_1 like family Cytochrom_B_C PF00032.12 EKG18222.1 - 0.085 13.0 0.8 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF1687 PF07955.6 EKG18223.1 - 4.5e-15 55.8 1.4 3.6e-14 52.8 1.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) RRM_1 PF00076.17 EKG18224.1 - 0.19 11.3 0.0 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_8 PF08022.7 EKG18225.1 - 1.7e-24 85.6 0.0 3.3e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EKG18225.1 - 6.2e-21 74.9 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EKG18225.1 - 1.8e-15 57.1 11.1 1.8e-15 57.1 7.7 2.1 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EKG18225.1 - 0.00018 21.5 0.0 0.00053 20.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain PepSY_TM_2 PF13703.1 EKG18226.1 - 0.1 12.7 2.7 3.4 7.9 0.3 2.3 2 1 0 2 2 2 0 PepSY-associated TM helix bZIP_1 PF00170.16 EKG18228.1 - 4.6e-05 23.2 15.2 9.7e-05 22.2 5.0 2.2 1 1 1 2 2 2 1 bZIP transcription factor Zwint PF15556.1 EKG18228.1 - 0.0091 15.2 3.2 0.013 14.8 2.2 1.1 1 0 0 1 1 1 1 ZW10 interactor DUF972 PF06156.8 EKG18228.1 - 0.013 15.8 0.7 0.027 14.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4355 PF14265.1 EKG18228.1 - 0.019 14.9 2.5 0.03 14.2 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TSC22 PF01166.13 EKG18228.1 - 0.029 14.3 3.0 0.06 13.3 0.9 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EKG18228.1 - 0.074 12.8 20.0 0.83 9.5 5.8 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DUF904 PF06005.7 EKG18228.1 - 0.12 12.6 6.0 0.24 11.7 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) CAF-1_p150 PF11600.3 EKG18228.1 - 2.8 7.2 13.9 5.6 6.2 9.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mnd1 PF03962.10 EKG18228.1 - 3.5 7.2 6.2 5.1 6.7 4.3 1.2 1 0 0 1 1 1 0 Mnd1 family NYD-SP28_assoc PF14775.1 EKG18228.1 - 9.3 6.0 6.3 0.78 9.4 1.2 1.6 2 0 0 2 2 2 0 Sperm tail C-terminal domain Glyco_hydro_1 PF00232.13 EKG18229.1 - 1.7e-158 527.5 0.1 2.1e-158 527.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF1479 PF07350.7 EKG18230.1 - 1.6e-168 560.5 0.0 1.8e-168 560.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) E1-E2_ATPase PF00122.15 EKG18232.1 - 3.9e-47 160.2 0.1 6.3e-47 159.5 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG18232.1 - 1.3e-35 122.5 3.5 1.3e-35 122.5 2.4 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG18232.1 - 1.2e-30 107.5 0.0 6.3e-30 105.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG18232.1 - 2.6e-16 60.3 0.0 5.4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG18232.1 - 8.4e-16 57.7 0.0 1.6e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EKG18232.1 - 7.6e-15 54.1 0.0 3.4e-14 52.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EKG18232.1 - 2e-05 24.2 0.2 5.6e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.4 EKG18232.1 - 0.81 10.0 6.9 0.12 12.7 0.4 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF1625 PF07787.7 EKG18232.1 - 8.3 5.5 6.4 1.6 7.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Peroxidase_2 PF01328.12 EKG18233.1 - 1.9e-15 56.3 0.0 2.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 bZIP_1 PF00170.16 EKG18234.1 - 5.5e-05 23.0 1.3 0.00017 21.4 0.9 1.8 1 0 0 1 1 1 1 bZIP transcription factor Pyr_redox_2 PF07992.9 EKG18236.1 - 5e-29 101.6 1.4 7.8e-29 100.9 1.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG18236.1 - 2e-15 56.9 0.4 2e-15 56.9 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EKG18236.1 - 4.5e-14 51.7 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EKG18236.1 - 2.7e-09 37.3 0.1 1e-07 32.2 0.0 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EKG18236.1 - 8.7e-06 25.9 0.0 4.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.1 EKG18236.1 - 0.00012 21.7 0.0 0.00041 20.0 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 EKG18236.1 - 0.0003 19.8 0.0 0.039 12.8 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EKG18236.1 - 0.015 15.5 0.6 7.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EKG18236.1 - 0.016 14.8 0.7 0.032 13.8 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EKG18236.1 - 0.025 13.9 0.1 0.052 12.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1188 PF06690.6 EKG18236.1 - 0.068 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) 2-Hacid_dh_C PF02826.14 EKG18236.1 - 0.07 12.2 0.4 3.5 6.7 0.2 2.4 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EKG18236.1 - 0.17 10.5 0.3 0.39 9.3 0.1 1.6 1 1 1 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EKG18236.1 - 0.49 10.1 4.1 2.2 8.0 0.0 2.6 3 0 0 3 3 2 0 FAD-NAD(P)-binding Pkinase PF00069.20 EKG18237.1 - 1.7e-64 217.4 0.0 2.6e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG18237.1 - 4.5e-36 124.2 0.0 1.4e-30 106.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKG18237.1 - 1.7e-05 23.9 0.0 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EKG18237.1 - 0.0017 18.1 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKG18237.1 - 0.0051 16.1 0.0 0.0093 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EKG18237.1 - 0.0091 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_31 PF01055.21 EKG18238.1 - 1.3e-164 548.2 0.3 1.6e-164 547.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG18238.1 - 0.0018 18.0 0.2 0.013 15.3 0.1 2.5 3 0 0 3 3 3 1 Galactose mutarotase-like DUF3687 PF12459.3 EKG18239.1 - 0.73 9.1 4.0 8 5.7 0.1 2.5 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein TRAP-gamma PF07074.7 EKG18239.1 - 3.5 7.1 5.8 1.2 8.6 1.2 1.9 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) A2M PF00207.17 EKG18240.1 - 0.13 11.8 0.1 1.1 8.8 0.0 2.0 1 1 0 1 1 1 0 Alpha-2-macroglobulin family ADH_N PF08240.7 EKG18241.1 - 4.8e-27 93.8 0.8 1.2e-26 92.5 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG18241.1 - 2.3e-06 27.1 0.0 0.00023 20.7 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EKG18241.1 - 0.0061 16.1 0.3 0.0061 16.1 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated PAF-AH_p_II PF03403.8 EKG18242.1 - 3e-22 78.4 0.0 4.6e-11 41.6 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II CDK2AP PF09806.4 EKG18242.1 - 0.019 15.2 2.2 0.028 14.6 1.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Abhydrolase_5 PF12695.2 EKG18242.1 - 0.032 13.9 0.1 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Prolamin_like PF05617.6 EKG18243.1 - 0.2 11.8 2.6 0.2 11.7 0.4 2.0 2 0 0 2 2 2 0 Prolamin-like Histidinol_dh PF00815.15 EKG18244.1 - 4.3e-178 592.1 7.9 6e-178 591.6 5.5 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EKG18244.1 - 2.2e-26 91.3 0.2 4.2e-26 90.3 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EKG18244.1 - 8.9e-11 41.9 1.7 1.2e-10 41.4 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.12 EKG18244.1 - 0.021 14.7 0.4 0.051 13.5 0.3 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain ATP_synt_I PF03899.10 EKG18245.1 - 0.015 15.4 0.3 0.027 14.6 0.2 1.4 1 0 0 1 1 1 0 ATP synthase I chain RskA PF10099.4 EKG18245.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SpoIIIAH PF12685.2 EKG18245.1 - 0.057 12.9 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Myco_19_kDa PF05481.7 EKG18245.1 - 0.097 12.4 3.0 0.17 11.7 2.1 1.4 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Cation_ATPase_C PF00689.16 EKG18245.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Clr2 PF10383.4 EKG18246.1 - 3.2e-12 46.6 0.0 1.5e-10 41.1 0.0 2.5 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 IncA PF04156.9 EKG18247.1 - 0.12 11.9 41.2 0.16 11.5 8.3 3.2 1 1 2 3 3 3 0 IncA protein DEP PF00610.16 EKG18247.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NPV_P10 PF05531.7 EKG18247.1 - 0.65 10.2 3.9 2.4 8.4 1.2 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 EKG18247.1 - 4.6 6.3 34.2 0.41 9.7 4.5 3.0 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EKG18247.1 - 6.8 6.5 36.1 2.9 7.7 9.8 3.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Cluap1 PF10234.4 EKG18247.1 - 9 5.4 26.4 12 5.0 1.7 2.5 1 1 1 2 2 2 0 Clusterin-associated protein-1 Alkyl_sulf_dimr PF14863.1 EKG18249.1 - 1.2e-46 158.4 0.1 4.4e-46 156.6 0.1 1.9 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 EKG18249.1 - 6.2e-21 74.9 0.1 1.1e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.1 EKG18249.1 - 5.5e-12 45.7 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.2 EKG18249.1 - 0.00034 20.2 0.0 0.00067 19.2 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_10 PF00331.15 EKG18250.1 - 3.2e-106 355.0 0.1 3.6e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Clc-like PF07062.7 EKG18251.1 - 0.012 14.8 1.8 0.012 14.8 1.3 2.6 2 1 0 2 2 2 0 Clc-like DUF3357 PF11837.3 EKG18252.1 - 0.14 12.0 0.7 0.9 9.4 0.0 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) DUF776 PF05604.6 EKG18253.1 - 2.7 8.1 7.6 14 5.8 4.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF776) Mpv17_PMP22 PF04117.7 EKG18254.1 - 5.4e-26 90.0 0.9 6.4e-26 89.7 0.7 1.1 1 0 0 1 1 1 1 Mpv17 / PMP22 family Abhydrolase_5 PF12695.2 EKG18255.1 - 1.3e-10 41.2 0.1 2.2e-10 40.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG18255.1 - 1.8e-09 37.8 1.4 7.4e-09 35.8 0.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EKG18255.1 - 0.0094 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EKG18255.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) TrkH PF02386.11 EKG18257.1 - 9.1e-91 304.0 8.1 1.2e-87 293.8 1.7 2.1 2 0 0 2 2 2 2 Cation transport protein DUF1118 PF06549.7 EKG18257.1 - 0.29 11.2 1.2 1.7 8.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1118) Senescence PF06911.7 EKG18258.1 - 5.7e-45 153.1 7.3 8.5e-45 152.6 5.0 1.3 1 0 0 1 1 1 1 Senescence-associated protein PgaD PF13994.1 EKG18261.1 - 0.034 13.6 0.6 0.093 12.2 0.4 1.7 1 0 0 1 1 1 0 PgaD-like protein DUF4231 PF14015.1 EKG18261.1 - 2.8 7.9 6.9 0.19 11.7 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) HSP90 PF00183.13 EKG18263.1 - 5.5e-208 691.6 12.9 6.8e-208 691.3 8.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EKG18263.1 - 1.4e-12 47.4 0.2 4.5e-12 45.7 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EKG18263.1 - 2.4e-10 40.1 0.0 4.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EKG18263.1 - 0.037 13.8 0.2 0.11 12.2 0.1 1.8 1 0 0 1 1 1 0 Tumour suppressor protein DUF1676 PF07898.8 EKG18263.1 - 0.094 13.0 0.2 0.094 13.0 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Metallophos PF00149.23 EKG18264.1 - 1.4e-44 151.9 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_4 PF12799.2 EKG18265.1 - 1.1e-19 69.5 4.7 5.2e-08 32.3 2.4 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG18265.1 - 8.3e-14 51.0 10.2 2.5e-09 36.7 1.9 4.0 3 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EKG18265.1 - 4.1e-11 41.2 8.3 0.038 14.0 0.1 6.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EKG18265.1 - 5.9e-07 28.9 6.8 6.2 7.2 0.1 5.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 EKG18265.1 - 1.3e-05 24.5 10.2 6.1 7.5 0.3 5.8 5 0 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 EKG18265.1 - 0.23 10.9 0.3 0.45 10.0 0.2 1.5 1 0 0 1 1 1 0 Leucine-rich repeat MFS_1 PF07690.11 EKG18266.1 - 8.4e-16 57.6 16.0 1.4e-15 56.8 11.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18266.1 - 2.1e-07 29.8 10.1 2.1e-06 26.6 7.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter Tannase PF07519.6 EKG18268.1 - 1.1e-06 27.6 0.0 2.1e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase ATP-synt_DE_N PF02823.11 EKG18269.1 - 1.6e-19 69.4 0.1 2.8e-19 68.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Septin PF00735.13 EKG18270.1 - 1.2e-13 50.7 0.0 1.9e-12 46.7 0.0 2.6 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EKG18270.1 - 2.5e-05 24.2 0.0 5.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKG18270.1 - 0.0022 17.2 0.0 0.0073 15.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EKG18270.1 - 0.0024 18.3 0.0 0.0064 16.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EKG18270.1 - 0.0073 16.3 0.4 0.064 13.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain MobB PF03205.9 EKG18270.1 - 0.029 14.0 0.0 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EKG18270.1 - 0.03 14.6 0.3 0.12 12.6 0.0 2.1 3 0 0 3 3 2 0 ABC transporter Dynamin_N PF00350.18 EKG18270.1 - 0.031 14.0 0.2 0.23 11.2 0.0 2.5 2 1 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 EKG18270.1 - 0.036 13.1 0.4 0.088 11.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 EKG18270.1 - 0.036 13.7 0.0 0.095 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EKG18270.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EKG18270.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EKG18270.1 - 0.083 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EKG18270.1 - 0.088 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EKG18270.1 - 0.093 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EKG18270.1 - 0.14 12.4 3.9 0.18 12.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 EKG18270.1 - 0.16 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.24 EKG18270.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTF2 PF02136.15 EKG18271.1 - 2.7e-22 79.3 1.1 5.8e-22 78.2 0.2 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Abhydrolase_6 PF12697.2 EKG18271.1 - 2.3e-18 66.9 0.1 2.3e-18 66.9 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG18271.1 - 1.4e-17 63.3 0.0 3e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EKG18271.1 - 1.3e-14 54.1 0.0 5.8e-14 52.0 0.0 2.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_6 PF14259.1 EKG18271.1 - 9.5e-10 38.3 0.0 2.6e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EKG18271.1 - 9.1e-09 34.8 0.1 1.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG18271.1 - 1.6e-05 24.6 0.0 3.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.15 EKG18271.1 - 0.008 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold PAF-AH_p_II PF03403.8 EKG18271.1 - 0.008 14.5 0.1 0.14 10.4 0.0 2.1 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II RRM_3 PF08777.6 EKG18271.1 - 0.027 14.3 1.3 0.045 13.6 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif NAD_binding_6 PF08030.7 EKG18272.1 - 1e-10 41.7 0.0 2e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EKG18272.1 - 1.4e-09 38.5 0.0 1.1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EKG18272.1 - 0.0098 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4190 PF13828.1 EKG18273.1 - 0.15 11.6 0.1 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) Amnionless PF14828.1 EKG18274.1 - 0.053 12.0 0.1 0.084 11.3 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4083 PF13314.1 EKG18274.1 - 1.6 8.6 4.0 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Baculo_11_kDa PF06143.6 EKG18274.1 - 3.6 7.0 5.6 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family FGGY_C PF02782.11 EKG18275.1 - 2.5e-25 89.2 0.1 5.4e-25 88.1 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EKG18275.1 - 3.2e-17 62.6 0.0 7.4e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Cation_efflux PF01545.16 EKG18276.1 - 1.2e-48 165.6 1.2 1.5e-48 165.3 0.8 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EKG18276.1 - 0.00047 19.2 0.0 0.0021 17.1 0.0 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Myb_DNA-bind_6 PF13921.1 EKG18277.1 - 0.00077 19.5 0.5 0.0068 16.4 0.3 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EKG18277.1 - 1 9.5 4.6 5 7.3 0.5 2.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain AAA PF00004.24 EKG18279.1 - 2e-47 160.7 0.0 9.2e-41 139.1 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG18279.1 - 2.4e-06 27.6 1.4 1.7e-05 24.8 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EKG18279.1 - 6.9e-06 25.5 0.0 3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EKG18279.1 - 7.6e-06 25.9 0.0 2.6e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EKG18279.1 - 1.9e-05 24.3 0.0 7.3e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EKG18279.1 - 5.3e-05 23.3 0.2 0.0024 17.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EKG18279.1 - 0.00016 21.7 0.0 0.0016 18.5 0.0 2.7 3 0 0 3 3 2 1 RNA helicase AAA_17 PF13207.1 EKG18279.1 - 0.003 18.3 2.6 0.016 16.0 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EKG18279.1 - 0.0038 17.1 0.0 0.045 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EKG18279.1 - 0.0045 15.7 0.0 0.0072 15.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EKG18279.1 - 0.0046 17.2 0.0 0.032 14.5 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG18279.1 - 0.0048 16.6 0.3 0.015 14.9 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EKG18279.1 - 0.0082 16.2 0.0 0.24 11.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EKG18279.1 - 0.0097 15.3 0.0 0.038 13.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EKG18279.1 - 0.014 15.7 0.0 0.014 15.7 0.0 3.7 5 1 0 5 5 2 0 ABC transporter AAA_33 PF13671.1 EKG18279.1 - 0.021 14.6 0.0 0.021 14.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.16 EKG18279.1 - 0.023 13.8 0.0 0.059 12.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EKG18279.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EKG18279.1 - 0.049 13.0 0.0 0.71 9.3 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain E3_binding PF02817.12 EKG18281.1 - 1.7e-05 24.3 0.3 0.00026 20.5 0.0 2.5 2 0 0 2 2 2 1 e3 binding domain Gag_spuma PF03276.9 EKG18281.1 - 2.8 6.1 9.1 0.41 8.9 0.3 2.0 2 0 0 2 2 2 0 Spumavirus gag protein FAP PF07174.6 EKG18281.1 - 9.8 5.3 22.6 0.22 10.8 3.7 2.1 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) ETRAMP PF09716.5 EKG18282.1 - 0.07 13.0 0.7 0.25 11.3 0.1 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Methyltransf_3 PF01596.12 EKG18283.1 - 1.2e-27 96.3 0.0 1.6e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EKG18283.1 - 2.7e-10 40.8 0.0 4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EKG18283.1 - 7.9e-09 36.2 0.0 1.1e-07 32.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18283.1 - 0.00017 21.2 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG18283.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EKG18283.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EKG18283.1 - 0.02 15.3 0.0 0.037 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EKG18283.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GCD14 PF08704.5 EKG18283.1 - 0.053 13.0 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF3425 PF11905.3 EKG18284.1 - 1.5e-17 63.7 0.1 5.6e-17 61.8 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Zn_clus PF00172.13 EKG18284.1 - 7.9e-09 35.2 9.9 1.4e-08 34.4 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1793 PF08760.6 EKG18285.1 - 5.6e-37 127.2 0.2 5.6e-37 127.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EKG18285.1 - 0.003 16.7 0.1 0.0054 15.9 0.1 1.4 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal DUF2040 PF09745.4 EKG18286.1 - 1.3e-37 128.4 27.4 1.3e-37 128.4 19.0 4.0 2 2 2 4 4 4 4 Coiled-coil domain-containing protein 55 (DUF2040) LLC1 PF14945.1 EKG18287.1 - 0.37 11.1 15.9 0.14 12.4 4.1 2.6 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Phage_Gp23 PF10669.4 EKG18287.1 - 1.2 9.2 8.4 3.6 7.7 5.8 1.8 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HSP70 PF00012.15 EKG18287.1 - 4 5.2 6.5 5.6 4.7 4.5 1.1 1 0 0 1 1 1 0 Hsp70 protein FadA PF09403.5 EKG18287.1 - 6.8 6.7 12.9 5.8 6.9 7.5 2.0 2 0 0 2 2 2 0 Adhesion protein FadA RNA_pol_Rpb2_6 PF00562.23 EKG18288.1 - 8e-125 416.5 0.1 1.5e-124 415.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EKG18288.1 - 1.6e-54 183.9 0.0 2.5e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EKG18288.1 - 2.3e-39 134.8 0.0 4.6e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EKG18288.1 - 3.3e-29 100.9 0.0 7.9e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EKG18288.1 - 1.3e-23 82.5 0.2 3.7e-23 81.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EKG18288.1 - 6.9e-23 80.1 0.1 1.5e-22 79.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EKG18288.1 - 5.3e-21 74.3 0.4 1.2e-20 73.1 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_zinc_N PF00107.21 EKG18289.1 - 9.1e-35 119.0 0.2 1.4e-34 118.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG18289.1 - 1.1e-12 48.9 0.0 2.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG18289.1 - 1.8e-06 27.6 0.0 2.2e-05 24.1 0.0 2.3 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EKG18289.1 - 0.019 14.5 0.8 0.032 13.8 0.5 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EKG18289.1 - 0.04 13.9 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EKG18289.1 - 0.065 13.2 0.4 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding URO-D PF01208.12 EKG18289.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) ubiquitin PF00240.18 EKG18290.1 - 9.8e-18 63.3 0.0 1.7e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EKG18290.1 - 2.7e-09 36.5 0.0 6.4e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EKG18290.1 - 2e-08 33.8 0.0 3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EKG18290.1 - 6.6e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EKG18290.1 - 7.1e-05 22.6 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EKG18290.1 - 0.032 14.7 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.1 EKG18290.1 - 0.1 12.8 0.1 0.31 11.3 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Cu_amine_oxid PF01179.15 EKG18292.1 - 8.9e-15 54.3 0.0 1.5e-14 53.5 0.0 1.2 1 1 1 2 2 2 1 Copper amine oxidase, enzyme domain Zn_clus PF00172.13 EKG18293.1 - 1.1e-06 28.3 7.7 1.9e-06 27.7 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EKG18294.1 - 3.8e-15 55.2 0.0 8.8e-15 54.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG18294.1 - 1.1e-12 47.6 0.0 2.4e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EKG18294.1 - 6.1e-11 42.7 0.0 9.8e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.1 EKG18294.1 - 9.4e-10 38.2 0.0 3.8e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kelch_4 PF13418.1 EKG18296.1 - 2.4e-28 97.6 10.2 7.1e-09 35.2 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EKG18296.1 - 7.1e-27 92.8 1.0 7.6e-07 28.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EKG18296.1 - 2.8e-26 90.5 4.8 4.7e-06 26.5 0.1 5.4 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.20 EKG18296.1 - 5.7e-21 73.7 4.7 1.8e-05 24.1 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EKG18296.1 - 1.6e-18 65.6 6.0 0.00048 19.7 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EKG18296.1 - 3.1e-18 65.3 12.1 5.6e-07 29.5 0.0 6.0 6 0 0 6 6 6 3 Galactose oxidase, central domain BTB PF00651.26 EKG18296.1 - 8.7e-11 41.8 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EKG18296.1 - 0.15 11.9 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 BTB And C-terminal Kelch UPF0197 PF05251.7 EKG18297.1 - 0.023 15.0 5.6 0.034 14.4 3.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) Rad1 PF02144.11 EKG18298.1 - 4.1e-88 294.7 0.0 4.7e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 COesterase PF00135.23 EKG18299.1 - 1.2e-101 341.0 0.0 1.5e-101 340.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG18299.1 - 9.3e-05 22.0 0.5 0.00043 19.9 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Bromodomain PF00439.20 EKG18300.1 - 3e-25 87.9 1.5 5.6e-25 87.0 1.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EKG18300.1 - 9.2e-09 35.2 0.1 2.4e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG18300.1 - 1.4e-08 34.7 0.7 3.3e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PHD PF00628.24 EKG18300.1 - 1.2e-05 24.8 8.4 2.8e-05 23.7 5.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EKG18300.1 - 0.014 15.4 2.1 0.035 14.2 1.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Acetyltransf_3 PF13302.1 EKG18300.1 - 0.09 12.9 0.1 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PHD_2 PF13831.1 EKG18300.1 - 0.12 11.6 7.0 0.3 10.4 4.9 1.7 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EKG18300.1 - 0.26 11.0 10.0 0.039 13.6 4.1 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Dioxygenase_C PF00775.16 EKG18301.1 - 9.8e-12 44.5 0.1 1.5e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Dioxygenase Glyco_hydro_92 PF07971.7 EKG18302.1 - 1.7e-139 465.7 0.0 2.4e-74 250.7 0.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_3 PF00933.16 EKG18303.1 - 2e-90 302.8 0.0 2.7e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG18303.1 - 1.6e-52 178.3 0.3 5.9e-50 169.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG18303.1 - 1.6e-24 85.5 0.4 3.2e-24 84.6 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Fer2_4 PF13510.1 EKG18305.1 - 0.12 12.2 0.4 29 4.5 0.0 4.0 4 1 0 4 4 4 0 2Fe-2S iron-sulfur cluster binding domain End3 PF12761.2 EKG18306.1 - 0.18 11.4 2.1 0.19 11.3 0.1 1.8 2 1 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Gas_vesicle_C PF01304.12 EKG18308.1 - 6.6 6.4 10.3 13 5.5 7.1 1.4 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain CMD PF02627.15 EKG18309.1 - 4.8e-08 32.7 0.1 3e-07 30.1 0.0 2.2 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family zf-C2H2_4 PF13894.1 EKG18310.1 - 9.1e-05 22.5 11.9 0.087 13.2 0.0 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG18310.1 - 0.04 14.2 21.5 0.72 10.3 0.0 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EKG18310.1 - 0.098 12.5 0.7 0.67 9.9 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EKG18310.1 - 0.15 12.3 1.5 8.3 6.7 0.3 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Pecanex_C PF05041.10 EKG18311.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) F-box-like_2 PF13013.1 EKG18312.1 - 0.078 12.7 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Rdx PF10262.4 EKG18313.1 - 1.1e-28 98.9 0.0 1.6e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 Rdx family DUF4451 PF14616.1 EKG18313.1 - 0.067 12.9 0.9 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) Eclosion PF04736.7 EKG18313.1 - 0.084 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone DUF2838 PF10998.3 EKG18314.1 - 1.7e-46 156.7 9.3 1.7e-46 156.7 6.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Sugarporin_N PF11471.3 EKG18314.1 - 0.78 9.4 3.8 0.73 9.5 0.9 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Atg14 PF10186.4 EKG18314.1 - 0.86 8.4 3.6 1.3 7.8 2.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 EKG18314.1 - 9.7 6.1 7.8 2 8.3 3.2 1.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SMC_N PF02463.14 EKG18315.1 - 1.9e-59 200.5 0.0 1.4e-57 194.5 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EKG18315.1 - 1.5e-31 108.8 1.3 1.5e-30 105.6 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EKG18315.1 - 3.2e-11 43.9 21.0 3.2e-11 43.9 14.5 6.2 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EKG18315.1 - 1.7e-10 41.3 4.5 0.00011 22.2 0.2 3.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EKG18315.1 - 1.5e-08 34.0 0.0 3.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EKG18315.1 - 0.00018 20.7 27.1 0.019 14.1 1.0 4.8 3 2 1 5 5 5 4 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EKG18315.1 - 0.0022 17.7 2.1 0.0022 17.7 1.5 12.1 5 4 7 12 12 12 1 Prefoldin subunit COG2 PF06148.6 EKG18315.1 - 0.008 16.0 1.1 0.008 16.0 0.8 7.7 5 2 2 7 7 7 2 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_II PF06009.7 EKG18315.1 - 3.5 7.3 61.4 0.53 10.0 2.0 7.3 4 2 3 8 8 8 0 Laminin Domain II Pro_CA PF00484.14 EKG18316.1 - 4.1e-26 91.8 0.0 5.2e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase APH PF01636.18 EKG18317.1 - 0.011 15.5 0.7 0.018 14.7 0.5 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RPN7 PF10602.4 EKG18319.1 - 1.2e-46 158.3 0.2 1.6e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EKG18319.1 - 1.2e-12 48.0 0.4 1.8e-11 44.3 0.0 2.6 2 1 0 2 2 2 1 PCI domain DUF3199 PF11436.3 EKG18319.1 - 0.037 13.8 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) TPR_2 PF07719.12 EKG18319.1 - 0.052 13.4 0.3 4 7.5 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat SPX PF03105.14 EKG18319.1 - 0.095 12.4 0.1 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 SPX domain Glyco_transf_34 PF05637.7 EKG18321.1 - 0.013 15.0 0.1 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Glyco_hydro_3 PF00933.16 EKG18323.1 - 5.4e-94 314.5 0.0 7.3e-94 314.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG18323.1 - 1.7e-53 181.4 0.2 4.4e-53 180.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain PS_pyruv_trans PF04230.8 EKG18323.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase CPSase_sm_chain PF00988.17 EKG18324.1 - 6.9e-46 154.9 0.0 1.4e-45 154.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EKG18324.1 - 8.5e-45 152.5 0.0 1.3e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EKG18324.1 - 0.00016 21.1 0.4 0.0031 16.9 0.3 2.3 1 1 0 1 1 1 1 Peptidase C26 GRAM PF02893.15 EKG18325.1 - 1.2e-15 56.7 0.0 2.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Atg14 PF10186.4 EKG18325.1 - 1.1 8.1 4.6 1.9 7.3 3.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC37_N PF03234.9 EKG18326.1 - 0.049 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF972 PF06156.8 EKG18326.1 - 1.2 9.4 4.4 2.2 8.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 EKG18326.1 - 1.6 8.2 4.6 0.38 10.3 0.6 1.7 2 0 0 2 2 2 0 IncA protein Solute_trans_a PF03619.11 EKG18327.1 - 8.7e-84 281.0 27.2 1e-83 280.8 18.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ORC6 PF05460.8 EKG18328.1 - 0.12 11.4 12.8 0.15 11.1 8.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SAP PF02037.22 EKG18329.1 - 5.2e-11 41.7 0.1 1.8e-10 40.0 0.1 1.9 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.7 EKG18329.1 - 0.00024 20.7 0.1 0.00055 19.6 0.0 1.6 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain HeH PF12949.2 EKG18329.1 - 0.1 12.1 0.1 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain Armet PF10208.4 EKG18329.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Ank_5 PF13857.1 EKG18330.1 - 0.00011 22.3 0.1 0.00024 21.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG18330.1 - 0.0028 17.9 0.0 0.0067 16.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKG18330.1 - 0.0042 16.8 0.8 0.011 15.4 0.6 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 EKG18330.1 - 0.0076 16.3 0.1 0.094 13.0 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat XdhC_C PF13478.1 EKG18330.1 - 0.04 14.2 0.0 0.15 12.3 0.0 2.1 1 0 0 1 1 1 0 XdhC Rossmann domain Ank_4 PF13637.1 EKG18330.1 - 0.044 14.3 0.0 0.096 13.2 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DIOX_N PF14226.1 EKG18331.1 - 1.8e-25 89.7 0.0 6.3e-25 87.9 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG18331.1 - 4e-15 55.9 0.0 8.1e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Autophagy_N PF03986.8 EKG18332.1 - 5.1e-45 152.8 0.0 9.4e-45 151.9 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EKG18332.1 - 2.7e-22 78.7 0.4 4.8e-22 77.9 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EKG18332.1 - 1.5e-14 52.7 0.4 2.5e-14 52.0 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Tox-GHH PF15636.1 EKG18333.1 - 0.11 12.1 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Abhydrolase_6 PF12697.2 EKG18334.1 - 9.4e-21 74.7 7.8 4.8e-20 72.4 5.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG18334.1 - 3.7e-07 30.0 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG18334.1 - 0.00012 21.7 5.5 0.0029 17.1 3.8 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 EKG18335.1 - 0.00021 20.2 3.4 0.00021 20.2 2.4 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Peptidase_C12 PF01088.16 EKG18336.1 - 6.2e-53 179.1 0.0 7.1e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EKG18336.1 - 0.0093 16.5 0.0 0.02 15.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase-like domain SSrecog PF03531.9 EKG18337.1 - 4.9e-69 232.0 0.8 3.6e-68 229.2 0.6 2.3 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EKG18337.1 - 3.5e-26 91.0 2.2 8e-26 89.8 0.1 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Fungal_trans_2 PF11951.3 EKG18337.1 - 1e-11 44.0 0.0 2.8e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG18337.1 - 8.2e-08 32.0 5.5 1.6e-07 31.1 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps5 PF09325.5 EKG18340.1 - 3.5e-86 288.2 3.8 6.1e-86 287.4 2.6 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EKG18340.1 - 8.5e-25 86.7 0.2 2.2e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 PX domain LEF-9 PF05094.7 EKG18340.1 - 0.13 10.6 0.1 0.18 10.1 0.1 1.1 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) Peptidase_C50 PF03568.12 EKG18341.1 - 1.1e-101 340.3 0.0 8.1e-101 337.4 0.0 2.2 1 1 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EKG18341.1 - 2.3e-09 37.0 16.2 4.5e-05 23.3 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKG18341.1 - 0.00097 18.8 16.9 0.31 11.0 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG18341.1 - 0.0075 16.8 17.5 12 6.8 0.1 8.6 8 1 1 9 9 9 1 Tetratricopeptide repeat PYRIN PF02758.11 EKG18341.1 - 0.0082 15.8 0.1 0.027 14.1 0.1 1.9 1 0 0 1 1 1 1 PAAD/DAPIN/Pyrin domain TPR_1 PF00515.23 EKG18341.1 - 0.068 12.8 12.6 0.88 9.2 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKG18341.1 - 0.12 12.0 18.0 1.2 8.8 0.1 5.2 5 0 0 5 5 5 0 TPR repeat TPR_19 PF14559.1 EKG18341.1 - 2 8.8 18.7 0.38 11.1 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4404 PF14357.1 EKG18341.1 - 4.1 7.8 10.3 0.64 10.4 0.4 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Methyltransf_23 PF13489.1 EKG18342.1 - 1.1e-11 44.7 0.0 1.5e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG18342.1 - 3.9e-09 36.1 0.0 1.1e-08 34.6 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EKG18342.1 - 3.1e-08 33.9 0.0 4.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18342.1 - 8.2e-08 31.9 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG18342.1 - 1.7e-06 28.0 0.1 3.1e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18342.1 - 3.6e-06 27.5 0.0 5.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18342.1 - 7.6e-06 26.3 0.0 1.5e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG18342.1 - 4.5e-05 23.7 0.0 7.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EKG18342.1 - 5.9e-05 22.6 0.1 8.5e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.6 EKG18342.1 - 0.00044 19.6 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EKG18342.1 - 0.00056 19.6 0.0 0.00086 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG18342.1 - 0.0011 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EKG18342.1 - 0.0033 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 EKG18342.1 - 0.0048 15.6 0.0 0.008 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EKG18342.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EKG18342.1 - 0.025 13.6 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.7 EKG18342.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.9 EKG18342.1 - 0.053 12.6 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 EKG18342.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase tRNA_U5-meth_tr PF05958.6 EKG18342.1 - 0.17 10.5 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase FAD_binding_3 PF01494.14 EKG18343.1 - 2.2e-18 66.4 6.2 1.3e-17 63.9 4.3 1.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG18343.1 - 0.0013 17.6 0.0 0.0056 15.5 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 EKG18343.1 - 0.0058 16.6 1.3 0.023 14.7 0.9 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG18343.1 - 0.25 10.2 4.4 0.44 9.4 0.7 2.5 2 1 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG18343.1 - 0.3 11.5 4.3 0.31 11.4 2.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short PF00106.20 EKG18345.1 - 4.2e-23 82.0 0.1 6.3e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG18345.1 - 1.5e-16 60.8 0.0 2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG18345.1 - 6.3e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG18345.1 - 0.0089 15.4 0.0 0.014 14.8 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG18345.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 EKG18345.1 - 0.14 10.9 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 EKG18346.1 - 3.6e-13 49.1 0.0 7.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG18346.1 - 3.5e-08 33.1 0.1 1.2e-07 31.3 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.19 EKG18347.1 - 4.3e-90 302.4 23.6 5.2e-90 302.1 16.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG18347.1 - 6.7e-17 61.2 60.8 1.1e-13 50.7 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nucleos_tra2_C PF07662.8 EKG18349.1 - 5.9e-70 235.0 0.2 5.9e-70 235.0 0.2 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EKG18349.1 - 1.9e-24 85.8 2.8 1.9e-24 85.8 2.0 2.8 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EKG18349.1 - 0.007 16.2 10.2 0.007 16.2 7.1 3.4 4 1 0 4 4 4 1 Nucleoside recognition ATP1G1_PLM_MAT8 PF02038.11 EKG18349.1 - 6.9 5.7 7.8 0.67 9.0 1.4 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family SBDS PF01172.13 EKG18350.1 - 2.2e-26 91.4 0.9 2.6e-26 91.2 0.6 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EKG18350.1 - 0.042 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage XkdN-like protein CorA PF01544.13 EKG18350.1 - 0.084 11.8 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RhoGEF PF00621.15 EKG18351.1 - 4.1e-26 91.9 0.0 7.5e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain Ras PF00071.17 EKG18352.1 - 2.8e-40 137.3 0.0 4.4e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Ras family PDZ PF00595.19 EKG18352.1 - 1.4e-06 28.3 0.0 2.9e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Miro PF08477.8 EKG18352.1 - 1.7e-06 28.5 0.0 3.6e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG18352.1 - 1.8e-05 24.0 0.0 3.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PDZ_2 PF13180.1 EKG18352.1 - 2.6e-05 24.0 0.0 7e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain DUF4054 PF13262.1 EKG18352.1 - 0.012 15.8 0.2 0.028 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Amidase PF01425.16 EKG18353.1 - 2.2e-74 250.9 0.9 2.7e-74 250.5 0.6 1.1 1 0 0 1 1 1 1 Amidase NPR2 PF06218.6 EKG18357.1 - 6.5e-133 443.5 0.0 1.9e-132 442.0 0.0 1.6 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EKG18357.1 - 0.012 14.2 0.1 1.8 7.0 0.0 2.9 2 1 1 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Bap31 PF05529.7 EKG18358.1 - 1.3e-66 223.7 0.2 1.5e-66 223.5 0.1 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 EKG18358.1 - 0.033 13.6 2.7 0.57 9.7 0.1 3.3 3 1 1 4 4 4 0 Septum formation initiator TMF_DNA_bd PF12329.3 EKG18358.1 - 0.058 13.2 3.7 0.5 10.1 0.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Geminin PF07412.7 EKG18358.1 - 0.078 12.6 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Geminin DUF641 PF04859.7 EKG18358.1 - 0.089 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Ada3 PF10198.4 EKG18359.1 - 1.4e-40 138.0 0.1 2.1e-40 137.4 0.1 1.3 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 EKG18361.1 - 3.9e-13 49.0 4.9 3.9e-13 49.0 3.4 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKG18361.1 - 2.1e-07 30.4 4.8 4.4e-07 29.4 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG18361.1 - 2.4e-07 30.6 4.9 5.1e-07 29.6 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG18361.1 - 6.7e-07 29.3 0.7 2.2e-06 27.6 0.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EKG18361.1 - 4.1e-06 26.3 2.6 7.8e-06 25.4 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG18361.1 - 1.1e-05 25.0 4.2 2e-05 24.2 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EKG18361.1 - 0.0029 17.4 0.3 0.0074 16.1 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EKG18361.1 - 0.007 16.0 0.9 0.018 14.7 0.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.1 EKG18361.1 - 0.046 13.4 4.8 0.11 12.2 0.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 EKG18361.1 - 0.15 11.5 3.2 0.36 10.3 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EKG18361.1 - 0.21 11.1 5.0 0.49 10.0 3.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EKG18361.1 - 0.42 10.6 2.1 0.82 9.7 1.4 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EKG18361.1 - 0.65 9.7 3.9 1.2 8.9 2.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EKG18361.1 - 0.91 9.5 6.6 1.9 8.5 2.8 2.5 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_4 PF15227.1 EKG18361.1 - 1.6 8.6 6.5 2.4 8.0 3.7 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EKG18361.1 - 1.7 8.6 5.2 4.4 7.3 3.0 2.1 2 1 0 2 2 1 0 FANCL C-terminal domain MFS_1 PF07690.11 EKG18363.1 - 3.1e-33 114.9 52.7 8.1e-33 113.5 36.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sel1 PF08238.7 EKG18364.1 - 9.8e-39 130.9 43.0 7.6e-07 29.5 0.1 13.3 13 0 0 13 13 13 10 Sel1 repeat MFS_1 PF07690.11 EKG18366.1 - 2.7e-39 134.8 26.7 5.2e-39 133.9 18.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18366.1 - 2e-09 36.5 3.8 2e-09 36.5 2.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EKG18366.1 - 0.0031 15.9 7.5 0.0031 15.9 5.2 2.8 3 1 0 3 3 3 1 MFS/sugar transport protein FTR1 PF03239.9 EKG18368.1 - 0.039 12.9 0.3 0.065 12.1 0.1 1.4 1 1 0 1 1 1 0 Iron permease FTR1 family DUF2834 PF11196.3 EKG18368.1 - 0.17 12.0 1.6 0.2 11.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) Rab5ip PF07019.7 EKG18368.1 - 0.2 11.8 1.8 0.43 10.7 1.3 1.5 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) PAP2 PF01569.16 EKG18368.1 - 0.52 10.0 3.6 2.2 7.9 2.5 1.8 1 1 0 1 1 1 0 PAP2 superfamily Cation_efflux PF01545.16 EKG18369.1 - 1.9e-07 30.4 0.3 2e-07 30.3 0.2 1.0 1 0 0 1 1 1 1 Cation efflux family PAP2 PF01569.16 EKG18370.1 - 5.7e-09 35.7 1.5 5.9e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily Amidohydro_5 PF13594.1 EKG18374.1 - 2.1e-13 49.8 0.2 1.5e-12 47.1 0.1 2.4 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EKG18374.1 - 5.2e-05 23.4 0.1 6.4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG18374.1 - 0.00041 20.1 0.2 0.00066 19.4 0.2 1.4 1 1 0 1 1 1 1 Amidohydrolase family DUF758 PF05527.6 EKG18374.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF758) GMC_oxred_C PF05199.8 EKG18375.1 - 6.1e-29 101.1 0.0 1.2e-28 100.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EKG18375.1 - 4.2e-25 88.5 0.0 3.5e-22 78.8 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 EKG18375.1 - 1.4e-05 24.1 0.2 0.078 11.8 0.0 2.7 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG18375.1 - 0.00064 19.7 0.1 0.004 17.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG18375.1 - 0.0099 14.8 0.0 0.021 13.7 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EKG18375.1 - 0.014 14.2 0.0 0.039 12.8 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EKG18375.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG18375.1 - 0.1 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.17 EKG18376.1 - 0.003 16.1 0.0 0.0033 16.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_2 PF13639.1 EKG18377.1 - 1.6e-12 47.0 5.9 1.6e-12 47.0 4.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EKG18377.1 - 2.1e-08 33.6 2.4 4.3e-08 32.6 1.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG18377.1 - 1e-07 31.8 3.8 2.1e-07 30.8 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG18377.1 - 1.3e-05 24.8 3.3 2.5e-05 23.9 2.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG18377.1 - 2.1e-05 24.0 2.3 2.1e-05 24.0 1.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EKG18377.1 - 3.2e-05 23.9 9.4 0.0001 22.3 6.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger RINGv PF12906.2 EKG18377.1 - 0.00013 21.9 1.6 0.00013 21.9 1.1 2.3 3 2 0 3 3 2 1 RING-variant domain zf-RING_6 PF14835.1 EKG18377.1 - 0.039 13.7 1.9 0.09 12.5 1.1 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EKG18377.1 - 0.051 13.4 5.4 0.1 12.4 3.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3377 PF11857.3 EKG18377.1 - 0.052 13.1 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) zf-RING_UBOX PF13445.1 EKG18377.1 - 0.053 13.2 0.5 0.13 11.9 0.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger PHD PF00628.24 EKG18377.1 - 0.21 11.2 5.0 0.62 9.7 3.5 1.9 1 1 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 EKG18377.1 - 1.4 8.9 12.1 1.8 8.6 5.3 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EKG18377.1 - 1.7 8.2 8.4 1.5 8.3 4.6 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Baculo_RING PF05883.6 EKG18377.1 - 2.3 8.0 6.9 2.8 7.7 1.0 2.3 1 1 1 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EKG18377.1 - 7.3 6.5 8.1 1.5 8.7 2.5 2.2 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING Cutinase PF01083.17 EKG18378.1 - 4.7e-44 150.2 8.2 2.5e-43 147.9 5.7 1.8 1 1 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EKG18378.1 - 1.5e-05 24.7 0.3 4.7e-05 23.0 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_9 PF10081.4 EKG18378.1 - 7.8e-05 21.5 0.1 0.0001 21.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family PE-PPE PF08237.6 EKG18378.1 - 9.7e-05 21.8 0.4 0.00014 21.3 0.3 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 EKG18378.1 - 0.00011 21.8 0.1 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EKG18378.1 - 0.0013 18.9 0.1 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_2 PF02230.11 EKG18378.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 EKG18378.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.8 EKG18378.1 - 0.052 13.1 0.3 0.082 12.4 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG18378.1 - 0.076 12.8 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EKG18378.1 - 0.14 11.4 0.1 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Zn_clus PF00172.13 EKG18379.1 - 0.0075 16.1 1.3 0.013 15.4 0.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4527 PF15030.1 EKG18379.1 - 0.067 12.4 1.6 0.084 12.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Nramp PF01566.13 EKG18380.1 - 7.1e-89 298.0 16.3 7.1e-89 298.0 11.3 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein His_Phos_2 PF00328.17 EKG18381.1 - 1.3e-27 97.0 0.0 1.7e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF2414 PF10309.4 EKG18381.1 - 0.12 12.1 0.2 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) Glyco_hydro_76 PF03663.9 EKG18382.1 - 1.1e-145 485.6 28.0 1.4e-145 485.3 19.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF3500 PF12006.3 EKG18384.1 - 1.8e-86 289.9 0.0 2.1e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) DUF165 PF02592.10 EKG18385.1 - 0.062 13.4 1.8 0.11 12.7 1.2 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 Bul1_N PF04425.7 EKG18387.1 - 2.4e-08 32.9 0.1 6.3e-08 31.6 0.1 1.7 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.7 EKG18387.1 - 3.4e-06 26.4 0.0 5.1e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus Arrestin_N PF00339.24 EKG18387.1 - 0.00072 19.4 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain AflR PF08493.5 EKG18389.1 - 0.0015 17.6 0.2 0.0021 17.1 0.2 1.3 1 1 0 1 1 1 1 Aflatoxin regulatory protein Tweety PF04906.8 EKG18389.1 - 0.098 11.0 0.7 0.24 9.7 0.1 1.8 1 1 1 2 2 2 0 Tweety Aminotran_1_2 PF00155.16 EKG18390.1 - 3e-33 115.2 0.0 3.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKG18390.1 - 0.0074 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase 2_5_RNA_ligase2 PF13563.1 EKG18391.1 - 1.1e-15 57.6 0.1 1.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily NTP_transferase PF00483.18 EKG18392.1 - 2.6e-48 164.5 0.0 6.2e-48 163.2 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EKG18392.1 - 1.8e-15 55.6 12.4 2.3e-09 36.3 1.5 4.0 2 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EKG18392.1 - 6.3e-11 42.6 0.0 8.6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EKG18392.1 - 1.2e-06 27.9 1.7 1.2e-06 27.9 1.2 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EKG18392.1 - 0.078 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SRP40_C PF05022.7 EKG18393.1 - 6.4e-24 84.2 1.3 1.8e-23 82.7 0.4 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain LisH PF08513.6 EKG18393.1 - 0.00014 21.4 0.4 0.00028 20.5 0.3 1.5 1 0 0 1 1 1 1 LisH TATR PF03430.8 EKG18393.1 - 1 7.9 25.8 1.2 7.6 17.9 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Sec3_C PF09763.4 EKG18394.1 - 9.6e-211 701.6 0.1 1.3e-210 701.2 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EKG18394.1 - 1e-29 102.1 0.0 1.9e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 EKG18394.1 - 8.2e-05 21.3 1.7 0.00014 20.5 0.3 1.8 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C_2 PF15278.1 EKG18394.1 - 0.091 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Sec3 exocyst complex subunit TPR_14 PF13428.1 EKG18396.1 - 8.1e-05 22.9 3.8 0.046 14.3 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat FAT PF02259.18 EKG18396.1 - 0.00029 19.9 1.3 0.00059 18.9 0.3 1.9 2 1 0 2 2 2 1 FAT domain TPR_11 PF13414.1 EKG18396.1 - 0.0028 17.2 0.1 2.6 7.7 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 EKG18396.1 - 0.0094 15.6 0.1 0.65 9.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG18396.1 - 0.013 15.3 0.0 2.4 8.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EKG18396.1 - 0.015 15.6 1.1 13 6.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 EKG18396.1 - 0.093 13.4 1.2 40 5.0 0.1 4.1 4 0 0 4 4 4 0 Sel1 repeat HrpB2 PF09487.5 EKG18396.1 - 0.097 12.8 0.8 0.19 11.9 0.6 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) TPR_16 PF13432.1 EKG18396.1 - 0.16 12.7 7.1 11 6.8 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.6 EKG18397.1 - 4.5e-19 68.4 2.0 4.5e-19 68.4 1.4 4.3 4 2 0 4 4 4 1 U3 snoRNA associated Fungal_trans PF04082.13 EKG18398.1 - 0.0047 15.8 0.1 0.0075 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PH_10 PF15411.1 EKG18399.1 - 1.3e-23 83.4 0.0 2.1e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EKG18399.1 - 2.6e-09 36.9 0.1 1.6e-08 34.3 0.1 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EKG18399.1 - 5.7e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain F-box-like PF12937.2 EKG18400.1 - 6.5e-05 22.5 0.6 0.0003 20.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like ETF PF01012.16 EKG18401.1 - 2.8e-24 85.6 0.2 3.5e-24 85.3 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Lipoprotein_3 PF00938.12 EKG18401.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipoprotein ArfGap PF01412.13 EKG18402.1 - 1.6e-32 111.7 0.2 2.8e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf adh_short PF00106.20 EKG18403.1 - 2.1e-10 40.7 0.3 2.2e-10 40.6 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG18403.1 - 5.4e-10 39.2 0.1 5.6e-10 39.1 0.1 1.0 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EKG18403.1 - 0.0018 17.5 0.1 0.0023 17.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.15 EKG18403.1 - 0.0037 17.3 0.0 0.0043 17.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EKG18403.1 - 0.004 16.0 0.0 0.0049 15.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EKG18403.1 - 0.012 14.5 0.1 0.014 14.3 0.1 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EKG18403.1 - 0.016 14.9 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EKG18403.1 - 0.036 14.4 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.1 EKG18403.1 - 0.036 13.8 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Transketolase_C PF02780.15 EKG18403.1 - 0.057 13.3 0.9 0.47 10.4 0.1 2.0 1 1 1 2 2 2 0 Transketolase, C-terminal domain NAD_binding_10 PF13460.1 EKG18403.1 - 0.058 13.3 0.4 1.4 8.9 0.2 2.1 1 1 0 1 1 1 0 NADH(P)-binding ThiF PF00899.16 EKG18403.1 - 0.32 10.7 2.8 1.9 8.3 1.9 2.1 1 1 0 1 1 1 0 ThiF family EntA_Immun PF08951.5 EKG18404.1 - 0.19 11.9 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 Enterocin A Immunity Lactamase_B_3 PF13483.1 EKG18405.1 - 7.1e-05 22.5 0.1 0.00017 21.3 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EKG18405.1 - 0.022 14.2 1.2 0.039 13.5 0.7 1.7 1 1 0 1 1 1 0 Beta-lactamase superfamily domain zf-CCHC PF00098.18 EKG18406.1 - 1.4e-42 141.5 61.0 9.6e-08 31.6 1.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EKG18406.1 - 2.9e-08 33.2 44.0 0.087 12.5 0.8 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EKG18406.1 - 6.5e-07 28.9 40.7 0.011 15.4 0.2 7.1 4 2 0 4 4 4 3 Zinc knuckle UDPGP PF01704.13 EKG18407.1 - 9.7e-59 198.9 0.0 1.4e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Fer4_20 PF14691.1 EKG18407.1 - 0.0076 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster RRP7 PF12923.2 EKG18408.1 - 3.8e-30 104.5 6.2 7.1e-30 103.7 4.3 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EKG18408.1 - 0.037 13.6 0.0 0.28 10.8 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-3_zeta PF05091.7 EKG18408.1 - 0.34 9.4 3.8 0.44 9.1 2.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SGL PF08450.7 EKG18411.1 - 4.9e-27 94.8 0.1 6.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EKG18411.1 - 4.9e-05 23.2 0.0 0.00018 21.4 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EKG18411.1 - 0.00066 19.6 0.2 0.004 17.0 0.0 2.3 2 0 0 2 2 2 1 Arylesterase Reg_prop PF07494.6 EKG18411.1 - 0.012 15.5 1.1 0.61 10.2 0.3 3.7 3 0 0 3 3 3 0 Two component regulator propeller PQQ PF01011.16 EKG18411.1 - 0.16 11.5 1.6 0.44 10.1 0.0 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.1 EKG18411.1 - 0.99 9.7 4.1 19 5.7 0.1 3.8 3 1 0 3 3 3 0 PQQ-like domain MFS_1 PF07690.11 EKG18412.1 - 5e-26 91.2 28.7 8.7e-18 64.1 6.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Endonuc-EcoRV PF09233.6 EKG18412.1 - 0.076 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease EcoRV Hydantoinase_B PF02538.9 EKG18414.1 - 1.3e-18 66.5 0.0 1.7e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EKG18414.1 - 1.6e-15 56.9 0.2 4.1e-15 55.6 0.1 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Vitelline_membr PF10542.4 EKG18415.1 - 0.16 11.6 1.0 0.31 10.7 0.7 1.5 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region LRR_4 PF12799.2 EKG18416.1 - 0.044 13.4 0.1 8 6.1 0.0 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Bul1_C PF04426.7 EKG18419.1 - 9.4e-06 25.0 0.1 2.3e-05 23.7 0.1 1.7 1 1 1 2 2 2 1 Bul1 C terminus Bul1_N PF04425.7 EKG18419.1 - 0.00086 17.9 1.0 0.011 14.3 0.0 2.0 1 1 1 2 2 2 2 Bul1 N terminus DIOX_N PF14226.1 EKG18420.1 - 1.8e-11 44.5 0.0 3.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG18420.1 - 5.4e-10 39.4 0.0 9.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UbiD PF01977.11 EKG18423.1 - 4.3e-132 440.4 0.0 1.1e-131 439.1 0.0 1.6 2 0 0 2 2 2 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase p450 PF00067.17 EKG18424.1 - 2.1e-47 161.7 0.0 3.1e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MIP PF00230.15 EKG18425.1 - 3.1e-29 102.0 5.7 3.5e-29 101.8 4.0 1.0 1 0 0 1 1 1 1 Major intrinsic protein DAO PF01266.19 EKG18426.1 - 4.8e-39 134.2 2.4 6.5e-39 133.8 1.7 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.21 EKG18426.1 - 5.1e-13 48.4 0.1 1.2e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_8 PF13450.1 EKG18426.1 - 3.3e-08 33.4 0.5 7.3e-08 32.3 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG18426.1 - 1e-06 27.8 0.3 2.1e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EKG18426.1 - 1.2e-05 24.5 1.1 8.1e-05 21.8 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG18426.1 - 5.3e-05 23.1 0.2 0.0001 22.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG18426.1 - 9.2e-05 21.6 0.3 0.00016 20.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EKG18426.1 - 9.3e-05 21.6 0.3 0.00029 20.0 0.2 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EKG18426.1 - 0.00022 20.4 0.0 0.00054 19.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EKG18426.1 - 0.0013 17.7 0.1 0.002 17.0 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EKG18426.1 - 0.0016 18.8 0.2 0.0039 17.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EKG18426.1 - 0.021 14.4 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EKG18426.1 - 0.021 13.3 0.1 0.03 12.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EKG18426.1 - 0.03 14.3 0.3 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG18426.1 - 0.043 12.7 0.1 0.069 12.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EKG18426.1 - 0.065 12.6 0.2 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 EKG18428.1 - 1.6e-10 41.3 0.0 5.3e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18428.1 - 3.1e-08 33.9 0.0 5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG18428.1 - 4.6e-07 29.6 0.0 6.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG18428.1 - 2.1e-06 28.0 0.0 3.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18428.1 - 1.3e-05 24.8 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18428.1 - 8.2e-05 23.1 0.2 0.00015 22.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG18428.1 - 0.0003 20.8 1.8 0.0011 18.9 1.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Fungal_trans PF04082.13 EKG18429.1 - 3.4e-09 35.9 0.0 5.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PELOTA_1 PF15608.1 EKG18430.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain ketoacyl-synt PF00109.21 EKG18431.1 - 3.2e-76 256.1 0.0 7.1e-76 255.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG18431.1 - 5.1e-43 147.5 0.0 1.3e-42 146.2 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EKG18431.1 - 2.3e-33 114.5 0.7 4.4e-32 110.4 0.6 2.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EKG18431.1 - 2.9e-12 46.6 0.2 6.2e-12 45.5 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EKG18431.1 - 3.2e-05 23.0 0.2 6.1e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Zn_clus PF00172.13 EKG18432.1 - 5.5e-06 26.1 10.0 5.5e-06 26.1 6.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EKG18432.1 - 0.025 13.6 0.1 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein HET PF06985.6 EKG18433.1 - 2.4e-33 115.2 0.2 3.9e-33 114.5 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.1 EKG18434.1 - 0.029 14.6 0.1 0.029 14.6 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.9 EKG18434.1 - 0.78 9.2 2.3 8.8 5.8 0.2 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2 PF00096.21 EKG18434.1 - 1.8 9.0 8.7 0.47 10.8 0.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type SUD-M PF11633.3 EKG18436.1 - 0.031 13.5 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 Single-stranded poly(A) binding domain V-ATPase_G PF03179.10 EKG18437.1 - 8.6e-35 119.2 19.3 9.8e-35 119.0 13.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EKG18437.1 - 0.0088 15.8 20.1 0.0095 15.7 7.7 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) DAG_kinase_N PF14513.1 EKG18437.1 - 0.041 14.0 1.5 0.041 14.0 1.0 1.7 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus RRF PF01765.14 EKG18437.1 - 0.095 12.1 13.1 0.12 11.8 9.0 1.2 1 0 0 1 1 1 0 Ribosome recycling factor DUF2422 PF10337.4 EKG18437.1 - 0.16 10.7 3.4 0.17 10.6 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Nop25 PF09805.4 EKG18437.1 - 0.16 12.0 16.5 0.2 11.7 11.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CAF-1_p150 PF11600.3 EKG18437.1 - 0.18 11.1 22.1 0.21 10.9 15.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3552 PF12072.3 EKG18437.1 - 0.21 10.7 20.9 0.51 9.5 14.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DDRGK PF09756.4 EKG18437.1 - 0.31 10.4 17.7 0.38 10.1 12.3 1.0 1 0 0 1 1 1 0 DDRGK domain DUF2215 PF10225.4 EKG18437.1 - 0.34 10.3 2.1 0.38 10.1 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) MMR_HSR1_C PF08438.5 EKG18437.1 - 0.42 10.8 5.4 0.62 10.3 3.6 1.4 1 1 0 1 1 1 0 GTPase of unknown function C-terminal Colicin-DNase PF12639.2 EKG18437.1 - 0.48 10.6 8.0 1.4 9.1 5.5 1.8 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin HrpE PF06188.7 EKG18437.1 - 0.53 9.9 5.9 0.71 9.5 4.1 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DDE_Tnp_1 PF01609.16 EKG18437.1 - 0.59 9.6 3.2 0.7 9.3 2.2 1.1 1 0 0 1 1 1 0 Transposase DDE domain DNA_primase_lrg PF04104.9 EKG18437.1 - 0.91 8.7 5.4 1.1 8.5 3.8 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit InvH PF04741.7 EKG18437.1 - 0.94 9.3 3.9 1.2 8.9 2.5 1.4 1 1 0 1 1 1 0 InvH outer membrane lipoprotein DUF2203 PF09969.4 EKG18437.1 - 1.4 9.1 6.1 1.9 8.7 4.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Vfa1 PF08432.5 EKG18437.1 - 1.5 8.8 16.2 1.7 8.6 11.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 KfrA_N PF11740.3 EKG18437.1 - 1.6 9.1 9.6 0.31 11.4 3.6 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3987 PF13148.1 EKG18437.1 - 3.4 6.1 9.4 3.9 5.9 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RGS-like PF09128.6 EKG18437.1 - 3.5 7.0 9.1 5.9 6.3 6.3 1.4 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain DUF2151 PF10221.4 EKG18437.1 - 5.6 5.0 10.2 6 4.9 7.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator ATP-synt_F6 PF05511.6 EKG18437.1 - 6.1 6.8 9.4 2.6 7.9 3.4 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 DUF883 PF05957.8 EKG18437.1 - 7.3 7.0 10.8 59 4.1 6.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.4 EKG18437.1 - 8.1 5.2 10.9 8.8 5.1 7.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 K1 PF02960.9 EKG18438.1 - 0.076 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 K1 glycoprotein GFA PF04828.9 EKG18439.1 - 0.00096 19.0 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Amidohydro_1 PF01979.15 EKG18440.1 - 6.2e-07 29.3 0.0 9e-07 28.8 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKG18440.1 - 0.019 14.8 0.2 0.059 13.1 0.0 1.9 2 1 0 2 2 2 0 Amidohydrolase Metallophos PF00149.23 EKG18441.1 - 4.9e-10 39.1 3.5 1.4e-09 37.6 2.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG18441.1 - 0.0015 18.3 0.0 0.014 15.2 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Herpes_UL14 PF03580.9 EKG18443.1 - 0.0046 16.7 0.0 0.0059 16.3 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus UL14-like protein NmrA PF05368.8 EKG18447.1 - 2.2e-17 63.1 0.0 3.5e-17 62.4 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG18447.1 - 2e-14 54.0 0.1 4.4e-14 52.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG18447.1 - 0.00034 20.1 0.2 0.0021 17.5 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EKG18448.1 - 6.3e-35 120.5 3.4 8.2e-35 120.1 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG18448.1 - 2.4e-30 106.1 0.5 2.7e-30 105.8 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG18448.1 - 2.6e-19 69.5 2.3 3.9e-19 69.0 1.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG18448.1 - 1.1e-06 28.3 0.8 2.3e-06 27.2 0.6 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG18448.1 - 0.014 14.1 0.3 0.019 13.6 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 EKG18448.1 - 0.045 13.3 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain THF_DHG_CYH_C PF02882.14 EKG18448.1 - 0.051 12.6 0.1 0.14 11.2 0.1 1.8 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CoA_binding_2 PF13380.1 EKG18448.1 - 0.053 13.6 0.2 0.6 10.2 0.1 2.1 2 0 0 2 2 2 0 CoA binding domain Eno-Rase_NADH_b PF12242.3 EKG18448.1 - 0.23 11.2 2.7 0.27 11.0 0.9 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Metallophos_2 PF12850.2 EKG18449.1 - 1.9e-08 34.2 0.0 2.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1814 PF08843.6 EKG18449.1 - 3.5e-06 26.9 0.8 3.7e-05 23.6 0.0 2.5 2 1 1 3 3 3 1 Nucleotidyl transferase of unknown function (DUF1814) Metallophos PF00149.23 EKG18449.1 - 7.5e-05 22.2 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3247 PF11607.3 EKG18449.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) Fungal_trans_2 PF11951.3 EKG18450.1 - 0.003 16.2 0.2 0.0038 15.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1358 PF07096.6 EKG18451.1 - 0.14 11.8 2.1 3.6 7.2 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1358) Abhydrolase_6 PF12697.2 EKG18454.1 - 5.8e-12 45.9 0.1 9.3e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG18454.1 - 5.2e-10 39.2 0.0 8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG18454.1 - 0.00015 21.4 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EKG18454.1 - 0.0022 17.6 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKG18454.1 - 0.0026 17.2 0.1 0.037 13.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF3341 PF11821.3 EKG18454.1 - 0.072 12.5 0.6 0.35 10.3 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) Pkinase PF00069.20 EKG18457.1 - 2.1e-06 27.0 0.0 3.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HMG_box PF00505.14 EKG18458.1 - 0.0033 17.6 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 2 HMG (high mobility group) box Pkinase PF00069.20 EKG18458.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain EMP70 PF02990.11 EKG18459.1 - 2.7e-162 540.8 0.0 4.7e-162 540.0 0.0 1.4 1 1 0 1 1 1 1 Endomembrane protein 70 HWE_HK PF07536.9 EKG18460.1 - 0.017 15.5 0.6 0.026 14.9 0.4 1.3 1 0 0 1 1 1 0 HWE histidine kinase Reo_sigmaC PF04582.7 EKG18460.1 - 0.024 13.8 2.6 0.027 13.6 1.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EKG18460.1 - 0.075 12.7 0.7 0.095 12.4 0.5 1.3 1 1 0 1 1 1 0 Laminin Domain II Syntaxin_2 PF14523.1 EKG18460.1 - 0.08 12.9 0.5 0.1 12.6 0.3 1.2 1 0 0 1 1 1 0 Syntaxin-like protein PspA_IM30 PF04012.7 EKG18460.1 - 0.16 11.3 2.3 0.13 11.5 0.8 1.3 2 0 0 2 2 2 0 PspA/IM30 family DUF2580 PF10824.3 EKG18460.1 - 0.3 11.4 2.6 2.4 8.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2580) Arrestin_N PF00339.24 EKG18462.1 - 3.5e-15 56.1 0.1 2e-12 47.1 0.0 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EKG18462.1 - 0.22 10.6 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Bul1 C terminus F-box-like PF12937.2 EKG18463.1 - 0.0017 17.9 0.4 0.0043 16.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like HET PF06985.6 EKG18464.1 - 1.8e-20 73.5 0.2 2.2e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF668 PF05003.7 EKG18464.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF668) DUF4164 PF13747.1 EKG18465.1 - 0.14 12.3 1.5 0.29 11.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Cortex-I_coil PF09304.5 EKG18465.1 - 0.17 11.9 3.2 0.36 10.8 2.2 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Tyrosinase PF00264.15 EKG18469.1 - 3.7e-23 82.8 3.5 2.3e-14 54.0 0.0 2.2 1 1 1 2 2 2 2 Common central domain of tyrosinase DEAD PF00270.24 EKG18471.1 - 2.9e-30 104.9 0.1 3.1e-17 62.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG18471.1 - 2e-21 75.6 0.1 5.2e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG18471.1 - 0.00015 21.6 0.1 0.0007 19.4 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EKG18471.1 - 0.0025 16.3 1.5 0.052 11.9 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1253) ATP-synt_G PF04718.10 EKG18472.1 - 1.6e-29 102.5 0.1 4.2e-29 101.2 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit T2SF PF00482.18 EKG18472.1 - 0.11 12.3 1.2 1.3 8.9 0.5 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Glyco_tranf_2_3 PF13641.1 EKG18474.1 - 1.1e-24 87.5 0.0 1.6e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EKG18474.1 - 1.9e-07 30.9 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EKG18474.1 - 1.2e-05 24.7 0.0 7e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 HupE_UreJ_2 PF13795.1 EKG18474.1 - 0.22 10.9 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 HupE / UreJ protein DHDPS PF00701.17 EKG18475.1 - 0.00022 19.9 0.0 0.00027 19.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DHDPS PF00701.17 EKG18476.1 - 8.8e-13 47.4 0.0 1e-12 47.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family adh_short_C2 PF13561.1 EKG18477.1 - 7.1e-10 39.0 0.0 1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG18477.1 - 0.00069 19.5 0.3 0.00094 19.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase SH3_9 PF14604.1 EKG18478.1 - 1.2e-13 50.4 0.0 2.2e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG18478.1 - 7.6e-11 41.2 0.0 1.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EKG18478.1 - 1.4e-09 37.6 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EKG18478.1 - 2.9e-08 33.8 0.0 7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EKG18478.1 - 4.4e-08 33.3 0.0 3.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 EKG18478.1 - 1.7e-07 31.3 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EKG18478.1 - 2.3e-06 26.9 0.0 4.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4454 PF14628.1 EKG18478.1 - 0.032 13.8 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) PH_8 PF15409.1 EKG18478.1 - 0.039 14.0 0.1 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_PNT PF02198.11 EKG18478.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain zf-MIZ PF02891.15 EKG18479.1 - 3.3e-11 42.4 2.2 6.1e-11 41.6 1.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EKG18479.1 - 0.21 11.1 2.0 0.51 9.8 1.4 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EKG18479.1 - 0.39 10.5 3.2 0.71 9.7 2.2 1.4 1 0 0 1 1 1 0 Ring finger domain ApbA PF02558.11 EKG18480.1 - 3.4e-30 104.4 0.0 4.8e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EKG18480.1 - 4.1e-20 72.0 0.0 8.2e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DAO PF01266.19 EKG18480.1 - 0.0019 17.1 0.1 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EKG18480.1 - 0.0037 16.3 0.0 0.0057 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EKG18480.1 - 0.0047 17.3 0.1 0.0092 16.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EKG18480.1 - 0.0066 16.2 0.4 0.012 15.4 0.3 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EKG18480.1 - 0.02 13.8 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EKG18480.1 - 0.062 12.9 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EKG18480.1 - 0.074 13.0 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 EKG18480.1 - 0.086 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EKG18480.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.20 EKG18481.1 - 0.021 13.9 0.0 0.049 12.7 0.0 1.7 1 1 0 1 1 1 0 Protein kinase domain Het-C PF07217.6 EKG18482.1 - 1.1e-271 902.3 0.6 1.4e-271 902.0 0.0 1.4 2 0 0 2 2 2 1 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.13 EKG18482.1 - 0.21 11.2 0.0 0.44 10.1 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C Clr5 PF14420.1 EKG18483.1 - 2.9e-16 59.1 4.2 9.8e-16 57.4 2.9 2.0 1 0 0 1 1 1 1 Clr5 domain DUF1743 PF08489.6 EKG18483.1 - 0.029 14.0 0.0 0.098 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1743) TAXi_C PF14541.1 EKG18483.1 - 0.078 12.5 0.0 0.27 10.7 0.0 1.9 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal SpoIIID PF12116.3 EKG18483.1 - 0.11 12.4 0.3 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 Stage III sporulation protein D Dynein_light PF01221.13 EKG18484.1 - 5.2e-41 138.5 1.9 6.1e-41 138.3 1.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF2578 PF10843.3 EKG18484.1 - 0.068 12.8 0.2 0.078 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) DUF3139 PF11337.3 EKG18484.1 - 0.1 12.9 0.2 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) RRM_1 PF00076.17 EKG18485.1 - 7.1e-77 253.0 3.8 6.6e-20 70.5 0.0 5.7 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG18485.1 - 8.2e-68 224.3 0.2 3.8e-17 62.0 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG18485.1 - 9.6e-32 108.6 0.0 2.9e-06 27.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKG18485.1 - 2e-05 24.2 1.1 1.2 8.9 0.0 4.8 5 0 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.1 EKG18485.1 - 0.00039 20.1 0.0 0.34 10.7 0.0 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif dsrm PF00035.20 EKG18487.1 - 0.0011 19.5 1.9 0.047 14.2 0.0 3.5 3 0 0 3 3 3 1 Double-stranded RNA binding motif ADH_zinc_N PF00107.21 EKG18488.1 - 1.2e-23 83.0 0.0 2.1e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG18488.1 - 1.2e-09 39.1 0.0 2.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EKG18488.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding EDR1 PF14381.1 EKG18490.1 - 0.14 11.6 0.1 0.59 9.6 0.0 1.8 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DM PF00751.13 EKG18491.1 - 1.2 8.7 7.0 0.42 10.1 2.0 2.1 2 1 0 2 2 2 0 DM DNA binding domain ADH_N PF08240.7 EKG18492.1 - 5.9e-06 26.0 1.1 1.5e-05 24.7 0.0 2.2 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain HMG_box PF00505.14 EKG18493.1 - 1.3e-14 54.2 0.9 2.6e-14 53.2 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKG18493.1 - 2.6e-07 30.9 0.6 6.9e-07 29.5 0.4 1.8 1 0 0 1 1 1 1 HMG-box domain Herpes_UL17 PF04559.7 EKG18493.1 - 8 4.9 13.8 15 4.0 9.6 1.4 1 0 0 1 1 1 0 Herpesvirus UL17 protein Maf PF02545.9 EKG18494.1 - 1.4e-37 128.7 0.1 1.7e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Maf PF02545.9 EKG18495.1 - 0.028 13.5 0.2 0.034 13.2 0.1 1.1 1 0 0 1 1 1 0 Maf-like protein FAP PF07174.6 EKG18495.1 - 0.46 9.7 7.4 0.51 9.5 5.1 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Scytalone_dh PF02982.9 EKG18496.1 - 6.7e-93 308.5 0.7 7.7e-93 308.3 0.5 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EKG18496.1 - 5.1e-08 32.8 0.2 7e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain RRM_1 PF00076.17 EKG18497.1 - 7e-43 144.1 0.0 5.3e-17 61.2 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG18497.1 - 2.4e-24 85.0 0.0 1.3e-09 37.8 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG18497.1 - 2.1e-22 78.6 0.0 1.8e-08 34.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKG18497.1 - 1.7e-06 27.8 0.0 6.6e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EKG18497.1 - 6.3e-05 22.6 0.1 0.0059 16.3 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Amidohydro_1 PF01979.15 EKG18498.1 - 1e-63 216.0 2.0 1.5e-63 215.4 1.4 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EKG18498.1 - 2.1e-55 186.0 0.6 4.4e-55 185.0 0.4 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EKG18498.1 - 5.8e-41 138.3 0.1 1e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EKG18498.1 - 1.3e-12 47.6 0.0 2.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EKG18498.1 - 2.8e-06 27.0 3.1 7.9e-06 25.6 2.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG18498.1 - 5.9e-05 22.4 0.6 0.00023 20.5 0.1 2.1 2 1 0 2 2 2 1 Amidohydrolase family CN_hydrolase PF00795.17 EKG18499.1 - 7.2e-31 106.9 0.0 1.8e-30 105.6 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase UPF0233 PF06781.7 EKG18500.1 - 0.24 11.0 0.2 0.51 9.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) S_100 PF01023.14 EKG18500.1 - 0.26 10.6 0.0 0.55 9.6 0.0 1.5 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain MFS_1 PF07690.11 EKG18501.1 - 0.018 13.7 17.4 0.12 11.0 12.7 1.9 1 1 1 2 2 2 0 Major Facilitator Superfamily fn3 PF00041.16 EKG18502.1 - 2.4e-08 33.9 0.5 8.1e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III domain Cellulose_synt PF03552.9 EKG18502.1 - 2.3 6.4 2.4 3.9 5.6 1.6 1.3 1 0 0 1 1 1 0 Cellulose synthase LNS2 PF08235.8 EKG18503.1 - 3.4e-70 234.6 0.0 5.1e-70 234.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EKG18503.1 - 1.7e-38 130.7 0.0 3.4e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 EKG18503.1 - 5.3 7.0 20.4 0.021 14.7 1.5 3.1 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator Utp11 PF03998.8 EKG18504.1 - 2.8e-27 96.0 16.3 3.5e-27 95.7 11.3 1.1 1 0 0 1 1 1 1 Utp11 protein HTH_33 PF13592.1 EKG18504.1 - 2.6 7.6 5.3 0.49 9.9 0.2 2.4 3 0 0 3 3 3 0 Winged helix-turn helix DUF106 PF01956.11 EKG18504.1 - 3.8 7.0 5.4 6.1 6.3 3.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1682 PF07946.9 EKG18504.1 - 6.9 5.4 19.4 0.12 11.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) adh_short PF00106.20 EKG18505.1 - 9.3e-23 80.9 0.0 1.3e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG18505.1 - 4.2e-10 39.5 0.0 8.3e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG18505.1 - 4.4e-08 33.2 0.0 6.2e-08 32.7 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EKG18505.1 - 0.023 13.3 0.0 0.1 11.2 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1116 PF06545.6 EKG18505.1 - 0.053 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Epimerase PF01370.16 EKG18505.1 - 0.068 12.5 0.0 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TFIID-31kDa PF02291.10 EKG18506.1 - 1.2e-29 102.7 0.0 1.9e-18 66.5 0.0 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Thg1C PF14413.1 EKG18510.1 - 2.2e-37 127.4 0.3 1.5e-30 105.3 0.0 2.0 2 0 0 2 2 2 2 Thg1 C terminal domain RNA_pol_Rpb1_1 PF04997.7 EKG18511.1 - 5.4e-112 374.3 0.0 9.7e-112 373.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EKG18511.1 - 3.5e-103 344.6 0.2 5.5e-103 344.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EKG18511.1 - 7.3e-71 237.4 0.0 1.7e-70 236.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EKG18511.1 - 4.4e-61 205.8 1.9 9.6e-61 204.7 1.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EKG18511.1 - 1.2e-46 158.3 0.0 2.3e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EKG18511.1 - 2.7e-41 140.4 2.3 5.4e-41 139.4 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EKG18511.1 - 1.9e-37 127.2 0.0 4.1e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EKG18511.1 - 4e-15 54.5 214.7 0.0061 16.5 7.0 14.8 6 2 8 17 17 17 13 RNA polymerase Rpb1 C-terminal repeat Vpu PF00558.14 EKG18511.1 - 0.4 10.2 1.6 1 8.9 1.1 1.6 1 0 0 1 1 1 0 Vpu protein LsmAD PF06741.8 EKG18511.1 - 2.8 8.0 4.7 3.6 7.7 0.3 2.5 2 0 0 2 2 2 0 LsmAD domain WD40 PF00400.27 EKG18512.1 - 1.2e-11 43.9 3.0 2.9e-07 30.0 0.2 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat eIF2A PF08662.6 EKG18512.1 - 0.00039 20.2 0.6 3 7.5 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EKG18512.1 - 0.011 14.0 0.0 0.087 11.1 0.0 2.2 2 1 0 2 2 2 0 Cytochrome D1 heme domain Pkinase PF00069.20 EKG18514.1 - 5.6e-08 32.2 0.0 1e-07 31.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain INO80_Ies4 PF08193.6 EKG18515.1 - 2.6e-57 194.3 21.4 3.6e-57 193.8 14.9 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 EKG18516.1 - 1.9e-38 131.4 0.0 2.9e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EKG18516.1 - 2e-26 92.5 0.2 3.3e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EKG18516.1 - 0.00086 18.9 1.0 0.002 17.7 0.1 2.1 2 0 0 2 2 2 1 LisH DUF2248 PF10005.4 EKG18516.1 - 0.15 10.9 0.1 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) MFS_1 PF07690.11 EKG18517.1 - 9.7e-42 142.9 16.1 1.4e-41 142.4 11.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.8 EKG18517.1 - 0.00024 19.3 6.7 0.00024 19.3 4.7 2.6 2 1 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 EKG18517.1 - 0.027 14.2 3.1 0.28 11.0 0.2 2.9 3 0 0 3 3 3 0 MFS_1 like family Noc2 PF03715.8 EKG18519.1 - 1.5e-120 401.6 0.0 2.9e-120 400.6 0.0 1.5 1 0 0 1 1 1 1 Noc2p family ABC_membrane_2 PF06472.10 EKG18519.1 - 3e-98 328.4 0.8 7.8e-98 327.0 0.1 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EKG18519.1 - 3.3e-14 53.3 0.0 2.1e-13 50.7 0.0 2.4 3 0 0 3 3 3 1 ABC transporter AAA_16 PF13191.1 EKG18519.1 - 0.0091 15.9 0.1 0.044 13.7 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EKG18519.1 - 0.038 13.5 0.4 0.14 11.7 0.0 2.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG18519.1 - 0.087 12.9 0.1 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKG18519.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EKG18519.1 - 0.12 11.5 0.1 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EKG18519.1 - 0.22 12.3 2.7 1.4 9.7 0.0 3.4 3 0 0 3 3 3 0 AAA domain VPS28 PF03997.7 EKG18520.1 - 1.9e-57 193.9 0.3 2.3e-57 193.6 0.2 1.1 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 EKG18520.1 - 0.0063 16.2 1.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 Gas vesicle protein G Imm3 PF14425.1 EKG18520.1 - 0.046 13.6 2.6 0.37 10.7 0.1 2.4 2 1 0 2 2 2 0 Immunity protein Imm3 C-C_Bond_Lyase PF15617.1 EKG18520.1 - 0.051 12.3 0.1 0.1 11.3 0.0 1.5 2 0 0 2 2 2 0 C-C_Bond_Lyase of the TIM-Barrel fold Vps23_core PF09454.5 EKG18520.1 - 0.092 12.3 0.4 0.22 11.1 0.3 1.6 1 0 0 1 1 1 0 Vps23 core domain ADH_N PF08240.7 EKG18521.1 - 1.6e-32 111.4 0.5 3.3e-32 110.4 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG18521.1 - 1.2e-22 79.8 1.6 3e-22 78.5 0.4 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_16 PF10294.4 EKG18521.1 - 3.6e-18 65.6 0.0 2.5e-17 62.8 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EKG18521.1 - 6.3e-06 26.7 0.0 0.073 13.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 EKG18521.1 - 0.00031 20.1 0.0 0.81 9.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.1 EKG18521.1 - 0.0066 16.0 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG18521.1 - 0.015 15.3 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EKG18521.1 - 0.017 16.0 0.0 0.041 14.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.13 EKG18521.1 - 0.032 14.2 0.2 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EKG18521.1 - 0.054 13.0 0.5 0.26 10.8 0.4 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain BTB PF00651.26 EKG18522.1 - 4.5e-08 33.0 0.0 7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain zf-LSD1 PF06943.7 EKG18523.1 - 0.055 13.0 0.4 0.21 11.2 0.3 2.0 1 0 0 1 1 1 0 LSD1 zinc finger DUF832 PF05734.6 EKG18523.1 - 0.19 10.8 3.2 0.36 10.0 2.2 1.3 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Fungal_trans PF04082.13 EKG18524.1 - 1.4e-25 89.6 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4661 PF15576.1 EKG18525.1 - 0.12 11.9 0.2 0.15 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) p450 PF00067.17 EKG18527.1 - 1.2e-40 139.4 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EKG18528.1 - 5.1e-28 98.1 0.0 1e-27 97.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG18528.1 - 5.4e-05 23.1 0.2 0.00018 21.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EKG18528.1 - 0.00051 19.2 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EKG18528.1 - 0.0075 15.2 2.5 0.041 12.7 1.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG18528.1 - 0.013 14.4 1.8 0.19 10.6 0.7 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EKG18528.1 - 0.021 14.5 0.5 0.047 13.4 0.4 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EKG18528.1 - 0.058 13.7 0.7 0.15 12.5 0.3 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG18528.1 - 0.061 13.3 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG18528.1 - 0.25 11.1 0.7 0.57 10.0 0.5 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG18528.1 - 0.35 9.6 2.3 0.54 9.0 0.6 2.0 3 0 0 3 3 3 0 FAD binding domain HATPase_c PF02518.21 EKG18529.1 - 9.3e-23 80.0 0.0 2.1e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG18529.1 - 3e-21 75.5 0.1 6.5e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EKG18529.1 - 6.5e-11 42.5 0.0 3e-09 37.1 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EKG18529.1 - 2.7e-08 33.8 0.0 8.5e-07 28.9 0.0 3.2 3 0 0 3 3 3 1 PAS fold HisKA PF00512.20 EKG18529.1 - 5.2e-08 32.7 3.3 6e-08 32.5 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EKG18529.1 - 1.1e-06 28.3 0.0 0.0004 20.1 0.0 2.7 2 0 0 2 2 2 1 PAS fold GAF_2 PF13185.1 EKG18529.1 - 7.8e-06 26.4 0.0 0.00029 21.3 0.0 2.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.1 EKG18529.1 - 3.7e-05 23.4 0.0 0.00037 20.2 0.0 2.7 3 0 0 3 3 3 1 PAS domain PAS_3 PF08447.6 EKG18529.1 - 0.00012 22.0 0.1 0.00033 20.6 0.0 1.9 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 EKG18529.1 - 0.00041 20.4 0.0 0.0099 15.9 0.0 2.8 2 0 0 2 2 2 1 GAF domain Inhibitor_G39P PF11417.3 EKG18529.1 - 0.11 12.5 0.1 0.39 10.7 0.1 1.9 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P LETM1 PF07766.8 EKG18530.1 - 0.054 12.5 0.2 0.074 12.0 0.1 1.1 1 0 0 1 1 1 0 LETM1-like protein DUF155 PF02582.9 EKG18533.1 - 2.6e-42 144.7 0.0 4.9e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RGS PF00615.14 EKG18535.1 - 1.6e-09 37.9 0.0 2.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain tRNA-synt_2b PF00587.20 EKG18536.1 - 4.2e-48 163.2 0.0 5.6e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKG18536.1 - 7.8e-09 35.3 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain MFS_1 PF07690.11 EKG18539.1 - 2e-22 79.4 41.7 8.1e-13 47.8 19.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18539.1 - 1.8e-15 56.4 22.7 6.3e-15 54.7 15.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter SSF PF00474.12 EKG18541.1 - 3.8e-06 25.8 4.5 5.3e-06 25.3 3.1 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family CoA_binding_3 PF13727.1 EKG18541.1 - 1.1 9.0 10.9 0.27 11.0 0.8 2.3 2 0 0 2 2 2 0 CoA-binding domain Epimerase PF01370.16 EKG18542.1 - 0.06 12.7 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1264 PF06884.6 EKG18543.1 - 7.2e-52 175.2 0.0 9.8e-52 174.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) ABM PF03992.11 EKG18547.1 - 0.12 12.3 0.1 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF3664 PF12406.3 EKG18549.1 - 0.12 13.0 0.4 0.19 12.3 0.3 1.3 1 0 0 1 1 1 0 Surface protein Adeno_E1A PF02703.9 EKG18550.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Early E1A protein FAA_hydrolase_N PF09298.6 EKG18550.1 - 0.13 12.2 0.1 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Zn_clus PF00172.13 EKG18551.1 - 0.014 15.2 8.1 0.014 15.2 5.6 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 EKG18552.1 - 1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EKG18552.1 - 8.6e-05 21.5 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 CsiD NmrA PF05368.8 EKG18554.1 - 3.4e-37 127.9 0.0 2e-36 125.4 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG18554.1 - 5.3e-07 29.8 0.5 7.2e-07 29.3 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EKG18554.1 - 5.8e-05 23.0 0.0 9.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 EKG18554.1 - 0.0033 16.9 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG18554.1 - 0.0098 14.6 0.0 0.015 14.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EKG18555.1 - 8.9e-39 133.1 37.1 3.5e-38 131.2 25.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_7 PF03492.10 EKG18556.1 - 7.7e-10 38.0 0.0 1.2e-09 37.4 0.0 1.3 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase Abhydrolase_6 PF12697.2 EKG18556.1 - 0.058 13.2 0.0 0.066 13.0 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4110 PF13422.1 EKG18557.1 - 0.036 13.8 4.7 0.048 13.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DUF262 PF03235.9 EKG18557.1 - 0.081 12.8 2.8 7.2 6.5 0.1 2.9 2 1 0 3 3 3 0 Protein of unknown function DUF262 HET PF06985.6 EKG18560.1 - 1.1e-22 80.7 0.0 2.1e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bile_Hydr_Trans PF04775.9 EKG18560.1 - 0.092 12.4 0.0 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Lsm_interact PF05391.6 EKG18560.1 - 0.26 10.7 1.0 0.58 9.6 0.7 1.6 1 0 0 1 1 1 0 Lsm interaction motif MR_MLE_C PF13378.1 EKG18563.1 - 5.5e-21 74.6 0.0 1.1e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EKG18563.1 - 8.4e-10 39.0 0.0 1.6e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EKG18563.1 - 8.6e-09 35.4 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 EKG18564.1 - 6.1e-28 97.4 0.3 6.1e-28 97.4 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG18564.1 - 3.5e-08 33.2 11.4 5.9e-08 32.4 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 EKG18565.1 - 4.7e-16 58.9 0.0 7.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18565.1 - 1.3e-05 25.7 0.1 5.1e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18565.1 - 2.6e-05 24.6 0.0 7.7e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18565.1 - 3.1e-05 23.6 0.0 0.00024 20.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18565.1 - 0.00016 22.0 0.0 0.0014 19.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG18565.1 - 0.0003 19.9 0.0 0.0017 17.4 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EKG18565.1 - 0.0017 18.6 0.0 0.012 15.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG18565.1 - 0.007 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EKG18565.1 - 0.0081 16.1 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG18565.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EKG18565.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EKG18565.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Acyl-CoA_dh_1 PF00441.19 EKG18566.1 - 1.4e-40 138.8 5.6 2e-40 138.3 3.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG18566.1 - 1e-28 100.1 0.4 2.9e-28 98.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EKG18566.1 - 6.9e-18 63.9 0.0 1.4e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EKG18566.1 - 2.4e-16 60.1 3.1 3.4e-16 59.7 2.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EKG18566.1 - 0.0082 15.5 0.7 0.04 13.2 0.2 2.2 2 1 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_hydro_71 PF03659.9 EKG18569.1 - 1.6e-23 82.8 0.6 2e-11 42.9 1.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 DUF900 PF05990.7 EKG18571.1 - 0.002 17.4 0.1 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EKG18571.1 - 0.003 17.1 0.0 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Host_attach PF10116.4 EKG18571.1 - 0.005 17.0 0.6 0.087 13.0 0.0 2.3 2 0 0 2 2 2 1 Protein required for attachment to host cells PE-PPE PF08237.6 EKG18571.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain LCAT PF02450.10 EKG18571.1 - 0.029 13.3 0.1 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HgmA PF04209.8 EKG18572.1 - 1.6e-129 432.0 0.0 1.8e-129 431.8 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Fungal_trans PF04082.13 EKG18573.1 - 1.7e-08 33.6 0.0 5.5e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pacs-1 PF10254.4 EKG18573.1 - 0.17 10.4 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein HD PF01966.17 EKG18575.1 - 3e-05 24.0 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 HD domain DUF676 PF05057.9 EKG18577.1 - 0.05 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EKG18577.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PE-PPE PF08237.6 EKG18577.1 - 0.089 12.2 0.0 13 5.1 0.0 2.4 2 0 0 2 2 2 0 PE-PPE domain Lbh PF15317.1 EKG18579.1 - 0.02 15.1 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein PepX_C PF08530.5 EKG18580.1 - 2.3e-36 125.7 0.7 4.1e-36 124.9 0.5 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EKG18580.1 - 1.3e-29 103.4 0.0 1.8e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EKG18580.1 - 3.7e-06 26.7 0.1 6.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG18580.1 - 6.1e-06 26.2 1.0 1.1e-05 25.4 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family HSP20 PF00011.16 EKG18584.1 - 4e-20 71.5 0.1 4.8e-13 48.8 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family Glycos_transf_1 PF00534.15 EKG18585.1 - 1.5e-25 89.5 0.0 3.6e-25 88.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EKG18585.1 - 1.3e-10 41.6 0.0 3.8e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EKG18585.1 - 9.5e-05 22.5 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.16 EKG18585.1 - 0.015 13.7 0.0 0.27 9.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase family 20 PEPCK_ATP PF01293.15 EKG18586.1 - 1.1e-24 86.8 0.0 1.3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase YbjQ_1 PF01906.12 EKG18587.1 - 2.9e-31 107.9 0.0 3.5e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Putative heavy-metal-binding CENP-B_dimeris PF09026.5 EKG18590.1 - 0.017 15.3 2.5 0.033 14.4 1.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_r3 PF04539.11 EKG18590.1 - 0.024 14.5 1.8 0.074 12.9 1.3 1.8 1 0 0 1 1 1 0 Sigma-70 region 3 DUF4611 PF15387.1 EKG18590.1 - 0.067 13.3 4.2 0.2 11.8 2.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFIIF_alpha PF05793.7 EKG18590.1 - 0.12 10.7 2.1 0.16 10.3 1.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleoplasmin PF03066.10 EKG18590.1 - 0.15 11.5 2.8 0.25 10.8 2.0 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF4604 PF15377.1 EKG18590.1 - 0.52 10.5 6.3 0.32 11.2 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) PBP1_TM PF14812.1 EKG18590.1 - 0.63 10.3 10.2 0.095 13.0 4.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2457 PF10446.4 EKG18590.1 - 2.9 6.4 13.8 3.2 6.3 6.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Methyltransf_23 PF13489.1 EKG18591.1 - 3.4e-18 65.8 0.0 5.6e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18591.1 - 8.7e-12 45.6 0.1 2.1e-10 41.1 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18591.1 - 1.6e-10 40.7 0.0 2.1e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18591.1 - 5.6e-10 39.5 0.0 3e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18591.1 - 1.6e-08 34.9 0.0 3.9e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG18591.1 - 2.2e-06 27.9 0.0 6.5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG18591.1 - 9.4e-06 24.8 0.0 2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EKG18591.1 - 0.00088 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.15 EKG18591.1 - 0.0067 15.5 0.0 0.019 14.0 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EKG18591.1 - 0.0099 15.9 0.0 0.084 12.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG18591.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EKG18591.1 - 0.016 14.3 0.0 0.061 12.4 0.0 1.8 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 EKG18591.1 - 0.083 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase BolA PF01722.13 EKG18591.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 BolA-like protein ADH_zinc_N_2 PF13602.1 EKG18596.1 - 0.0038 18.1 0.0 0.0039 18.0 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CASP_C PF08172.7 EKG18597.1 - 6e-06 25.4 2.5 7.1e-06 25.2 1.7 1.1 1 0 0 1 1 1 1 CASP C terminal HAP1_N PF04849.8 EKG18597.1 - 0.00052 19.0 1.5 0.00072 18.5 1.1 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region IncA PF04156.9 EKG18597.1 - 0.00074 19.1 2.8 0.00093 18.8 1.9 1.1 1 0 0 1 1 1 1 IncA protein DivIVA PF05103.8 EKG18597.1 - 0.00094 19.2 3.3 0.0014 18.6 2.3 1.3 1 0 0 1 1 1 1 DivIVA protein ADIP PF11559.3 EKG18597.1 - 0.0026 17.6 4.1 0.0034 17.2 2.8 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Lebercilin PF15619.1 EKG18597.1 - 0.0044 16.4 6.4 0.0064 15.9 4.5 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF2968 PF11180.3 EKG18597.1 - 0.0049 16.2 5.1 0.0049 16.2 3.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) Fmp27_WPPW PF10359.4 EKG18597.1 - 0.0085 14.5 1.5 0.0097 14.3 1.0 1.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF3498 PF12004.3 EKG18597.1 - 0.016 14.3 1.7 0.018 14.2 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) BLOC1_2 PF10046.4 EKG18597.1 - 0.026 14.6 2.1 0.034 14.2 1.5 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nsp1_C PF05064.8 EKG18597.1 - 0.028 14.0 1.2 0.043 13.4 0.8 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region DUF3510 PF12022.3 EKG18597.1 - 0.029 14.4 0.3 0.034 14.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) FTCD_C PF04961.7 EKG18597.1 - 0.038 13.3 0.6 0.065 12.6 0.4 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase CALCOCO1 PF07888.6 EKG18597.1 - 0.043 12.0 2.8 0.052 11.8 2.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SpoIIID PF12116.3 EKG18597.1 - 0.073 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Stage III sporulation protein D PTRF_SDPR PF15237.1 EKG18597.1 - 0.095 12.0 4.5 0.6 9.4 3.1 1.9 1 1 0 1 1 1 0 PTRF/SDPR family Spc42p PF11544.3 EKG18597.1 - 0.2 11.6 4.2 1.4 8.8 2.4 2.2 1 1 1 2 2 2 0 Spindle pole body component Spc42p TMF_DNA_bd PF12329.3 EKG18597.1 - 0.2 11.4 9.2 0.31 10.8 6.4 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding PhoU PF01895.14 EKG18597.1 - 0.26 11.7 3.8 0.43 11.0 2.6 1.4 1 1 0 1 1 1 0 PhoU domain DUF972 PF06156.8 EKG18597.1 - 0.38 11.1 2.3 0.59 10.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MbeD_MobD PF04899.7 EKG18597.1 - 0.63 9.9 4.6 2.2 8.2 0.4 2.3 1 1 1 2 2 2 0 MbeD/MobD like FliT PF05400.8 EKG18597.1 - 0.77 10.2 7.9 2 8.8 5.5 1.8 1 1 0 1 1 1 0 Flagellar protein FliT ABC_tran_2 PF12848.2 EKG18597.1 - 1.1 9.1 5.8 2.6 7.9 4.0 1.6 1 0 0 1 1 1 0 ABC transporter SlyX PF04102.7 EKG18597.1 - 1.1 9.6 5.8 2.1 8.7 2.0 2.3 1 1 1 2 2 2 0 SlyX DUF948 PF06103.6 EKG18597.1 - 1.5 8.7 3.6 11 5.8 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) p450 PF00067.17 EKG18598.1 - 1.6e-59 201.6 0.0 2.1e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 EKG18599.1 - 1e-35 123.5 0.0 1.3e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EKG18599.1 - 0.00015 21.5 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EKG18599.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG18599.1 - 0.00026 20.2 0.0 0.0004 19.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EKG18599.1 - 0.00087 19.2 0.2 0.0014 18.5 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EKG18599.1 - 0.0025 17.2 0.0 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PAE PF03283.8 EKG18599.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Pectinacetylesterase RVT_2 PF07727.9 EKG18600.1 - 8.9e-24 83.7 0.0 1.1e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.1 EKG18601.1 - 0.008 15.6 0.0 0.063 12.8 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain rve PF00665.21 EKG18601.1 - 0.012 15.7 0.0 0.05 13.7 0.0 2.1 3 0 0 3 3 3 0 Integrase core domain Abhydrolase_3 PF07859.8 EKG18604.1 - 1.4e-22 80.3 0.4 1.2e-16 60.9 0.1 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG18604.1 - 1.9e-12 46.8 0.0 4.8e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG18604.1 - 2.5e-10 40.2 0.4 3.8e-10 39.6 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG18604.1 - 1.7e-07 31.3 6.2 2.3e-07 30.9 4.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EKG18604.1 - 0.00012 21.4 0.0 0.12 11.6 0.0 2.5 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EKG18604.1 - 0.0011 18.4 0.0 1.3 8.3 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.23 EKG18604.1 - 0.0091 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF2048 PF09752.4 EKG18604.1 - 0.066 12.0 0.1 0.098 11.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) FAD_binding_4 PF01565.18 EKG18605.1 - 9.9e-19 67.1 2.8 3.2e-18 65.5 1.9 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG18605.1 - 2.7e-08 33.5 0.0 5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like CrtC PF07143.6 EKG18606.1 - 3.5e-06 26.5 0.9 7.2e-06 25.5 0.7 1.6 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Phage_sheath_1 PF04984.9 EKG18609.1 - 0.035 12.5 0.4 0.042 12.2 0.3 1.1 1 0 0 1 1 1 0 Phage tail sheath protein Fungal_trans PF04082.13 EKG18610.1 - 3e-27 95.1 0.0 7e-27 93.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG18610.1 - 0.039 13.8 2.9 0.076 12.9 2.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H PF00075.19 EKG18611.1 - 7.5e-06 26.3 0.2 1.2e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EKG18611.1 - 0.041 14.1 0.1 0.1 12.9 0.1 1.7 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase DUF3618 PF12277.3 EKG18616.1 - 0.024 14.6 1.0 0.024 14.6 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) ATP-synt_D PF01813.12 EKG18616.1 - 0.064 12.8 0.0 0.088 12.3 0.0 1.6 1 1 0 1 1 1 0 ATP synthase subunit D Glyco_hydro_7 PF00840.15 EKG18618.1 - 4.2e-164 546.0 11.5 4.7e-164 545.8 8.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Defensin_beta_2 PF13841.1 EKG18619.1 - 0.084 13.2 1.6 0.16 12.3 1.1 1.5 1 0 0 1 1 1 0 Beta defensin SSDP PF04503.8 EKG18621.1 - 0.073 12.8 1.7 0.13 11.9 1.2 1.3 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP p450 PF00067.17 EKG18622.1 - 5.2e-69 232.9 0.0 6.2e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 EKG18624.1 - 4.6e-30 104.3 0.0 6.4e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EKG18624.1 - 9.6e-26 89.8 0.0 1.6e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EKG18624.1 - 4.8e-06 26.5 0.0 0.00069 19.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EKG18624.1 - 0.009 15.9 0.0 0.078 12.9 0.0 2.2 1 1 0 1 1 1 1 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.13 EKG18625.1 - 3.1e-30 105.1 0.0 4.5e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EKG18625.1 - 8.4e-16 58.1 0.0 1.6e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EKG18625.1 - 7.7e-06 25.7 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EKG18625.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.12 EKG18625.1 - 0.01 16.1 0.0 0.33 11.3 0.0 3.4 3 0 0 3 3 3 0 Low-density lipoprotein receptor repeat class B PP2C_2 PF13672.1 EKG18626.1 - 0.018 14.4 0.2 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Prok-TraM PF09228.5 EKG18626.1 - 0.087 12.9 0.1 0.17 12.0 0.1 1.5 1 1 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM Crystall PF00030.14 EKG18627.1 - 0.1 12.4 0.5 0.16 11.8 0.3 1.4 1 1 0 1 1 1 0 Beta/Gamma crystallin peroxidase PF00141.18 EKG18628.1 - 8.6e-21 74.4 0.0 1.5e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PAN_4 PF14295.1 EKG18629.1 - 8.7e-14 50.9 18.0 2.2e-06 27.2 0.4 3.6 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.21 EKG18629.1 - 6.1e-07 29.1 9.7 0.0002 21.0 0.1 3.5 3 0 0 3 3 3 2 PAN domain PAN_3 PF08277.7 EKG18629.1 - 0.027 14.0 17.6 0.72 9.5 2.2 3.6 3 0 0 3 3 3 0 PAN-like domain PAN_2 PF08276.6 EKG18629.1 - 0.048 13.5 0.2 0.048 13.5 0.1 3.5 3 0 0 3 3 3 0 PAN-like domain SseC PF04888.7 EKG18629.1 - 0.61 9.3 13.9 1.3 8.3 9.6 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Glyco_hydro_43 PF04616.9 EKG18630.1 - 1.7e-28 99.5 0.6 2.9e-28 98.7 0.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Kelch_1 PF01344.20 EKG18630.1 - 0.015 14.8 0.0 1.9 8.1 0.0 3.0 2 0 0 2 2 2 0 Kelch motif MFS_1 PF07690.11 EKG18632.1 - 1.4e-08 33.8 44.8 1.4e-08 33.8 31.0 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3007 PF11460.3 EKG18632.1 - 0.1 12.7 0.6 0.37 10.8 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Fungal_trans PF04082.13 EKG18633.1 - 1.7e-25 89.3 0.1 2.7e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG18633.1 - 1.6e-05 24.7 4.1 2.6e-05 24.0 2.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EKG18634.1 - 7.1e-89 298.6 0.3 8.5e-89 298.4 0.2 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EKG18634.1 - 1.4e-38 132.5 0.0 3.7e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family Transp_cyt_pur PF02133.10 EKG18635.1 - 1.3e-99 333.7 35.5 1.6e-99 333.4 24.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FAD_binding_3 PF01494.14 EKG18636.1 - 8.9e-18 64.4 0.7 1.3e-09 37.6 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG18636.1 - 6.6e-08 32.4 0.9 1.5e-07 31.3 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG18636.1 - 9.6e-08 31.3 3.6 2.1e-06 26.9 0.4 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG18636.1 - 4.7e-06 25.6 2.8 8.2e-06 24.9 1.1 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG18636.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG18636.1 - 0.00013 22.1 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EKG18636.1 - 0.00035 19.7 0.1 0.21 10.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EKG18636.1 - 0.0013 19.0 0.4 0.0035 17.7 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EKG18636.1 - 0.0015 17.2 0.5 0.017 13.7 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 EKG18636.1 - 0.0017 16.9 0.5 0.0027 16.2 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EKG18636.1 - 0.0024 16.8 0.7 0.0042 16.0 0.5 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EKG18636.1 - 0.0025 16.9 0.1 0.0033 16.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG18636.1 - 0.0041 16.1 0.2 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EKG18636.1 - 0.0072 15.8 0.2 0.013 15.0 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EKG18636.1 - 0.011 14.8 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EKG18636.1 - 0.085 12.6 0.4 0.62 9.8 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EKG18636.1 - 0.13 11.8 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3987 PF13148.1 EKG18637.1 - 0.096 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ComA PF02679.10 EKG18638.1 - 1.5e-76 256.6 0.0 1.7e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) AP_endonuc_2 PF01261.19 EKG18638.1 - 0.021 14.1 0.0 2.6 7.3 0.0 2.6 2 1 0 3 3 3 0 Xylose isomerase-like TIM barrel NmrA PF05368.8 EKG18639.1 - 1.1e-12 47.7 0.0 1.6e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG18639.1 - 3.2e-07 30.5 0.1 4.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding GnsAB PF08178.6 EKG18639.1 - 0.059 13.0 0.2 0.26 10.9 0.1 2.0 2 0 0 2 2 2 0 GnsA/GnsB family DUF3105 PF11303.3 EKG18639.1 - 0.088 12.6 0.0 0.59 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) MFS_1 PF07690.11 EKG18641.1 - 2.6e-06 26.3 12.5 3.8e-06 25.8 8.7 1.2 1 1 0 1 1 1 1 Major Facilitator Superfamily NicO PF03824.11 EKG18641.1 - 0.021 14.1 0.4 0.021 14.1 0.3 1.7 2 0 0 2 2 2 0 High-affinity nickel-transport protein MFS_1 PF07690.11 EKG18642.1 - 1.2e-16 60.4 24.0 2e-16 59.6 16.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PIRT PF15099.1 EKG18642.1 - 0.75 9.0 2.2 4.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family YfhO PF09586.5 EKG18642.1 - 3.9 5.3 5.4 5.3 4.9 3.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OATP PF03137.15 EKG18642.1 - 5.8 4.8 7.4 85 0.9 4.9 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3435 PF11917.3 EKG18643.1 - 2.8e-87 293.1 0.4 3.7e-87 292.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF629 PF04780.7 EKG18644.1 - 0.00028 19.5 0.1 0.00045 18.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF629) DUF3505 PF12013.3 EKG18644.1 - 0.036 14.3 1.6 0.036 14.3 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) M-factor PF03855.8 EKG18646.1 - 3.1 7.8 5.5 0.56 10.2 0.4 2.2 2 0 0 2 2 2 0 M-factor SLY PF12485.3 EKG18648.1 - 1.8 8.7 8.2 4.3 7.5 5.7 1.5 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Pyr_redox_3 PF13738.1 EKG18651.1 - 4.3e-22 79.1 0.0 1e-21 77.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG18651.1 - 6.9e-11 41.0 0.0 6.5e-09 34.5 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG18651.1 - 6.5e-10 38.8 0.0 4.9e-08 32.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG18651.1 - 5.8e-07 28.8 0.0 1.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EKG18651.1 - 2.2e-06 26.8 0.0 0.00022 20.2 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EKG18651.1 - 2.7e-05 23.2 1.2 0.0011 17.9 0.3 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG18651.1 - 0.0019 18.0 1.1 0.51 10.1 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG18651.1 - 0.0038 17.5 0.1 2.9 8.3 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG18651.1 - 0.0078 16.0 1.4 4.4 7.0 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EKG18651.1 - 0.011 14.6 0.1 0.022 13.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EKG18651.1 - 0.013 14.4 0.5 0.24 10.2 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EKG18651.1 - 0.016 14.3 0.3 0.027 13.5 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EKG18651.1 - 0.022 13.6 0.7 0.88 8.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EKG18651.1 - 0.028 13.0 0.5 2.3 6.7 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.20 EKG18652.1 - 5.4e-17 62.2 1.2 8.7e-17 61.5 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG18652.1 - 2.6e-11 43.7 0.0 7.1e-11 42.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG18652.1 - 4.3e-06 26.5 0.5 3.5e-05 23.5 0.3 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG18652.1 - 0.00016 21.7 0.6 0.0018 18.3 0.1 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EKG18652.1 - 0.00098 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG18652.1 - 0.011 15.4 1.1 0.027 14.2 0.8 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 EKG18652.1 - 0.013 15.0 0.1 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PA PF02225.17 EKG18652.1 - 0.046 13.4 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 PA domain 2-Hacid_dh_C PF02826.14 EKG18652.1 - 0.058 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.17 EKG18653.1 - 1.8e-51 175.1 0.0 2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EKG18654.1 - 4e-09 36.2 0.0 4.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DUF1084 PF06454.6 EKG18655.1 - 2.6 7.0 5.3 0.22 10.5 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1084) zf-C2H2 PF00096.21 EKG18658.1 - 6.5e-06 26.1 15.0 0.22 11.9 0.0 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG18658.1 - 0.0019 18.4 17.1 1.5 9.3 0.1 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger Metallothio_PEC PF02068.11 EKG18658.1 - 3.1 8.2 9.9 8.4 6.8 1.1 3.0 1 1 2 3 3 3 0 Plant PEC family metallothionein Integrin_B_tail PF07965.7 EKG18658.1 - 4 7.9 6.5 4.3 7.8 0.0 2.5 2 1 2 4 4 4 0 Integrin beta tail domain Peptidase_S8 PF00082.17 EKG18659.1 - 4.7e-18 65.3 0.1 8.2e-18 64.5 0.1 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EKG18659.1 - 1.5e-05 25.3 0.0 3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EKG18659.1 - 0.00028 20.5 0.0 0.0009 18.9 0.0 1.7 1 1 0 1 1 1 1 PA domain SR-25 PF10500.4 EKG18660.1 - 0.015 14.7 4.2 0.019 14.4 2.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 EKG18660.1 - 0.36 10.8 6.7 0.52 10.3 4.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Med3 PF11593.3 EKG18660.1 - 1.8 7.7 5.8 2 7.5 4.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2186 PF09952.4 EKG18661.1 - 0.06 13.6 1.7 0.075 13.2 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) Sin_N PF04801.8 EKG18661.1 - 0.06 12.1 2.2 0.07 11.9 1.5 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region DUF3439 PF11921.3 EKG18661.1 - 0.29 10.8 4.1 0.35 10.6 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EKG18661.1 - 0.45 8.4 5.6 0.45 8.4 3.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4604 PF15377.1 EKG18661.1 - 0.89 9.7 8.7 1.2 9.3 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Crystall PF00030.14 EKG18662.1 - 0.046 13.5 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Haem_oxygenas_2 PF14518.1 EKG18663.1 - 1.6e-10 41.0 0.0 4.6e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Iron-containing redox enzyme tRNA-synt_1b PF00579.20 EKG18664.1 - 1.3e-34 119.6 0.0 9.6e-34 116.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) Pyridox_ox_2 PF12900.2 EKG18665.1 - 2.6e-41 140.7 0.0 3.4e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase 2OG-FeII_Oxy PF03171.15 EKG18666.1 - 4.1e-10 39.8 0.0 1e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fip1 PF05182.8 EKG18666.1 - 0.069 12.4 0.1 6.6 6.0 0.0 2.5 2 0 0 2 2 2 0 Fip1 motif VHP PF02209.14 EKG18666.1 - 0.092 12.4 0.1 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Villin headpiece domain MFS_1 PF07690.11 EKG18667.1 - 3.9e-36 124.4 34.0 6.3e-36 123.8 23.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18667.1 - 1.8e-12 46.5 10.5 1.8e-12 46.5 7.2 2.8 1 1 2 3 3 3 1 Sugar (and other) transporter Herpes_UL20 PF04544.7 EKG18667.1 - 0.0091 15.8 0.0 0.037 13.8 0.0 2.0 1 0 0 1 1 1 1 Herpesvirus egress protein UL20 DUF3328 PF11807.3 EKG18674.1 - 9e-50 169.3 0.2 1.2e-49 168.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EKG18675.1 - 2.8e-49 167.7 1.0 3.5e-49 167.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Gal-bind_lectin PF00337.17 EKG18675.1 - 0.0057 15.9 0.1 0.023 14.0 0.0 1.8 1 1 1 2 2 2 1 Galactoside-binding lectin Retro_M PF02813.9 EKG18675.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Retroviral M domain Acetyltransf_10 PF13673.1 EKG18678.1 - 4.3e-06 26.8 0.0 1.2e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG18678.1 - 5.5e-06 26.4 0.0 8.5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG18678.1 - 9.8e-06 25.5 0.0 1.7e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKG18678.1 - 0.003 17.2 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EKG18678.1 - 0.0074 16.1 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4328 PF14219.1 EKG18680.1 - 0.0014 17.9 0.1 0.0019 17.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) TarH PF02203.10 EKG18680.1 - 0.015 15.1 1.6 0.02 14.7 1.1 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue FtsL PF04999.8 EKG18680.1 - 0.029 14.0 0.4 0.041 13.5 0.3 1.2 1 0 0 1 1 1 0 Cell division protein FtsL Tetraspannin PF00335.15 EKG18680.1 - 0.061 12.5 0.1 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family 4HB_MCP_1 PF12729.2 EKG18680.1 - 0.11 11.8 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TadE PF07811.7 EKG18680.1 - 1.9 8.4 6.5 3.3 7.6 4.5 1.3 1 0 0 1 1 1 0 TadE-like protein GRP PF07172.6 EKG18680.1 - 1.9 8.9 11.3 6.4 7.3 7.9 1.8 1 1 0 1 1 1 0 Glycine rich protein family T_cell_tran_alt PF15128.1 EKG18680.1 - 9 5.8 6.9 3.4 7.1 0.5 2.4 3 0 0 3 3 3 0 T-cell leukemia translocation-altered Polyketide_cyc PF03364.15 EKG18691.1 - 0.068 13.1 0.0 0.085 12.8 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Uma2 PF05685.7 EKG18693.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease PucR PF07905.6 EKG18693.1 - 0.022 14.3 0.0 0.06 12.9 0.0 1.8 1 1 0 1 1 1 0 Purine catabolism regulatory protein-like family APC10 PF03256.11 EKG18693.1 - 0.063 12.8 0.1 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) Glyco_hydro_43 PF04616.9 EKG18694.1 - 7.1e-17 61.4 3.4 1.1e-16 60.8 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cyclin PF08613.6 EKG18695.1 - 7.1e-07 29.7 0.0 9.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EKG18695.1 - 0.0075 15.8 0.1 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain FecCD PF01032.13 EKG18696.1 - 0.066 12.0 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 FecCD transport family Fungal_trans_2 PF11951.3 EKG18698.1 - 5.3e-18 64.7 0.0 2.7e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Chromo PF00385.19 EKG18701.1 - 5e-08 32.4 0.3 5e-08 32.4 0.2 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC_4 PF14392.1 EKG18703.1 - 1.5 8.5 10.9 0.87 9.2 0.3 2.8 3 0 0 3 3 3 0 Zinc knuckle HsbA PF12296.3 EKG18704.1 - 1.3e-22 79.9 7.4 8.1e-22 77.3 4.5 2.0 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1484 PF07363.6 EKG18704.1 - 0.0039 17.5 0.1 0.033 14.5 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1484) FAD_binding_3 PF01494.14 EKG18706.1 - 8e-23 81.0 0.0 3.3e-14 52.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EKG18706.1 - 0.0018 17.2 0.9 0.83 8.4 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG18706.1 - 0.012 16.0 0.9 0.28 11.5 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DHDPS PF00701.17 EKG18709.1 - 1.2e-27 96.3 0.0 1.4e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aldo_ket_red PF00248.16 EKG18710.1 - 4.8e-57 192.9 0.0 5.8e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EKG18710.1 - 0.085 13.0 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Fungal_trans PF04082.13 EKG18711.1 - 1.2e-24 86.5 0.3 2.3e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL32 PF06070.6 EKG18711.1 - 0.21 10.0 1.0 0.32 9.3 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 AMP-binding PF00501.23 EKG18712.1 - 4e-31 107.8 0.1 4.4e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKG18713.1 - 6.6e-39 133.3 0.0 1e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EKG18713.1 - 6.7e-09 35.5 0.0 4.5e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EKG18713.1 - 8.4e-08 32.3 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EKG18713.1 - 0.011 15.6 0.6 0.076 12.9 0.4 2.4 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EKG18713.1 - 0.038 13.6 0.3 0.15 11.6 0.2 2.1 1 1 0 1 1 1 0 KR domain Topoisom_I_N PF02919.10 EKG18714.1 - 0.015 14.5 0.1 0.022 14.0 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PDEase_II PF02112.10 EKG18715.1 - 0.0048 15.8 0.0 0.0054 15.7 0.0 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II zf-CCHC_2 PF13696.1 EKG18716.1 - 0.014 14.9 0.7 0.014 14.9 0.5 1.6 2 0 0 2 2 2 0 Zinc knuckle SlyX PF04102.7 EKG18716.1 - 0.025 14.9 1.4 0.039 14.3 1.0 1.2 1 0 0 1 1 1 0 SlyX Anp1 PF03452.9 EKG18717.1 - 0.88 8.6 4.5 1.2 8.2 3.1 1.1 1 0 0 1 1 1 0 Anp1 DUF4381 PF14316.1 EKG18718.1 - 0.13 12.3 0.3 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CFEM PF05730.6 EKG18718.1 - 1.8 8.4 13.1 5.7 6.8 9.1 1.8 1 1 0 1 1 1 0 CFEM domain Phytase-like PF13449.1 EKG18719.1 - 6.3e-34 117.7 0.0 1.6e-33 116.3 0.0 1.7 1 1 0 1 1 1 1 Esterase-like activity of phytase Acetyltransf_1 PF00583.19 EKG18720.1 - 5.4e-12 45.5 0.4 7.9e-12 45.0 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG18720.1 - 3.4e-06 27.1 0.1 5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG18720.1 - 5.8e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG18720.1 - 0.021 14.5 0.1 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein CVNH PF08881.5 EKG18721.1 - 5.7e-30 103.6 0.2 6.2e-30 103.4 0.1 1.0 1 0 0 1 1 1 1 CVNH domain p450 PF00067.17 EKG18723.1 - 1.4e-59 201.8 0.0 2.1e-59 201.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EKG18723.1 - 5.4e-18 64.8 0.2 9.5e-18 63.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG18724.1 - 1.3e-33 116.2 22.8 1.3e-33 116.2 15.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18724.1 - 1.5e-10 40.3 29.4 2.9e-09 36.0 8.0 3.2 3 1 1 4 4 4 3 Sugar (and other) transporter TRI12 PF06609.8 EKG18724.1 - 1.3e-07 30.2 4.9 1.7e-07 29.8 1.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.14 EKG18725.1 - 3e-46 158.1 0.0 3.7e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EKG18725.1 - 1.2e-05 25.5 0.0 5.9e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG18725.1 - 6.9e-05 21.9 0.0 0.00063 18.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG18725.1 - 7.1e-05 22.7 0.0 0.00025 21.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EKG18725.1 - 0.0007 18.1 0.0 0.00097 17.7 0.0 1.1 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EKG18725.1 - 0.0023 17.0 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 EKG18725.1 - 0.0028 17.1 0.0 0.0078 15.6 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EKG18725.1 - 0.0048 15.8 0.1 0.028 13.2 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain XdhC_C PF13478.1 EKG18725.1 - 0.01 16.1 0.0 0.028 14.7 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain Pyr_redox_3 PF13738.1 EKG18725.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG18725.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG18725.1 - 0.055 12.3 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EKG18725.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG18725.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_23 PF13489.1 EKG18727.1 - 2.5e-20 72.8 0.1 3.9e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18727.1 - 2.6e-10 40.8 0.0 3.8e-09 37.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18727.1 - 2.9e-10 40.4 0.0 1.6e-09 38.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18727.1 - 1e-09 38.7 0.0 2.3e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18727.1 - 7.9e-08 32.0 0.0 6.9e-07 28.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG18727.1 - 4.8e-05 23.6 0.0 0.00017 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EKG18727.1 - 0.0002 20.4 0.0 0.00041 19.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EKG18727.1 - 0.0003 20.8 0.0 0.00064 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKG18727.1 - 0.0049 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EKG18727.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EKG18727.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EKG18727.1 - 0.015 14.6 0.1 0.065 12.6 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EKG18727.1 - 0.048 12.7 0.0 0.31 10.1 0.0 2.1 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EKG18727.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_2 PF00891.13 EKG18728.1 - 2.1e-20 72.9 0.0 2.7e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Herpes_gE PF02480.11 EKG18729.1 - 0.58 8.3 2.3 0.54 8.4 0.4 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E zf-C2H2 PF00096.21 EKG18731.1 - 2.5e-06 27.4 16.1 0.0026 17.9 3.4 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG18731.1 - 4.2e-06 26.7 12.7 0.014 15.6 3.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG18731.1 - 4.9e-05 23.3 13.8 0.0057 16.9 2.8 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger DUF2457 PF10446.4 EKG18731.1 - 0.028 13.1 0.4 0.035 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PAS_11 PF14598.1 EKG18731.1 - 0.067 13.1 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 PAS domain zf-C2H2_6 PF13912.1 EKG18731.1 - 0.21 11.5 7.7 0.14 12.0 1.9 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger SEP PF08059.8 EKG18732.1 - 4.3e-28 97.4 0.7 7.1e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EKG18732.1 - 2.2e-16 59.6 0.0 3.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EKG18732.1 - 1.8e-12 46.5 0.1 3.2e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EKG18732.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 UBA/TS-N domain CRAL_TRIO_N PF03765.10 EKG18732.1 - 0.11 12.6 0.1 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain TOM13 PF08219.6 EKG18733.1 - 6e-30 102.8 0.0 8.9e-30 102.2 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Mesothelin PF06060.7 EKG18735.1 - 0.091 10.7 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) OSR1_C PF12202.3 EKG18735.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C terminal Ank_2 PF12796.2 EKG18736.1 - 5.4e-12 45.8 0.1 9.2e-12 45.1 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG18736.1 - 7.6e-09 35.5 0.2 4e-06 26.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EKG18736.1 - 1e-08 34.5 0.6 6.6e-06 25.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EKG18736.1 - 1.2e-06 28.2 0.1 0.0087 16.2 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EKG18736.1 - 0.0018 18.7 0.1 0.074 13.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DYW_deaminase PF14432.1 EKG18737.1 - 0.0025 17.7 0.0 0.0055 16.6 0.0 1.3 1 1 0 1 1 1 1 DYW family of nucleic acid deaminases RTA1 PF04479.8 EKG18738.1 - 1.4e-49 168.6 0.6 2e-49 168.1 0.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 EKG18739.1 - 0.0008 19.2 11.9 0.0013 18.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_decarbox PF01536.11 EKG18740.1 - 8.8e-87 290.8 0.0 2.2e-60 204.0 0.0 3.1 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase Hid1 PF12722.2 EKG18742.1 - 8.8e-268 890.6 0.0 3.9e-267 888.5 0.0 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EKG18742.1 - 5.7e-88 295.7 0.0 7.7e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DASH_Spc19 PF08287.6 EKG18742.1 - 0.0096 15.5 0.0 0.39 10.3 0.1 2.7 2 0 0 2 2 2 1 Spc19 Helicase_C_3 PF13625.1 EKG18743.1 - 2.5e-23 82.2 0.0 3.6e-22 78.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG18743.1 - 6.5e-15 55.4 0.0 2.3e-14 53.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKG18743.1 - 4.4e-10 39.2 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKG18743.1 - 1.8e-09 36.8 0.1 4.7e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EKG18743.1 - 9.5e-06 25.2 0.0 3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase GDPD_2 PF13653.1 EKG18744.1 - 0.011 15.9 0.4 0.022 14.9 0.3 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Pyr_redox_2 PF07992.9 EKG18745.1 - 1.1e-06 28.6 0.1 0.029 14.2 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG18745.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EKG18745.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2235 PF09994.4 EKG18746.1 - 1.9e-28 99.6 0.0 2.9e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Avl9 PF09794.4 EKG18749.1 - 3.9e-146 486.3 0.0 5.6e-146 485.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EKG18749.1 - 1.8e-08 34.0 0.3 0.00018 21.1 0.0 2.4 1 1 1 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EKG18749.1 - 3e-05 23.4 10.4 8e-05 22.0 1.6 3.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) ketoacyl-synt PF00109.21 EKG18751.1 - 2.1e-70 237.0 0.1 3.9e-70 236.2 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG18751.1 - 6.2e-38 129.2 0.1 1.3e-37 128.2 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EKG18751.1 - 2.1e-37 129.1 0.0 3.2e-33 115.4 0.1 2.6 2 0 0 2 2 2 2 Acyl transferase domain PS-DH PF14765.1 EKG18751.1 - 5.9e-26 91.3 0.0 1.2e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EKG18751.1 - 6.3e-23 80.8 8.7 1.3e-11 44.5 1.6 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 EKG18751.1 - 1.4e-14 54.1 0.0 2.6e-13 50.0 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG18751.1 - 1.1e-11 44.6 0.4 1.7e-09 37.5 0.0 3.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_12 PF08242.7 EKG18751.1 - 3.2e-11 43.5 0.0 7.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 EKG18751.1 - 5.2e-11 42.1 0.0 3.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thiolase_N PF00108.18 EKG18751.1 - 1.5e-07 30.6 0.0 2.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.1 EKG18751.1 - 3.2e-07 30.2 0.0 7.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EKG18751.1 - 7.2e-07 29.3 1.2 4e-06 26.8 0.8 2.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 EKG18751.1 - 4.8e-06 26.2 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_2 PF02230.11 EKG18751.1 - 3.4e-05 23.3 0.0 0.0073 15.7 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Methyltransf_18 PF12847.2 EKG18751.1 - 0.00049 20.6 0.0 0.0023 18.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Peptidase_S15 PF02129.13 EKG18751.1 - 0.00051 19.5 0.0 10 5.4 0.0 3.2 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_11 PF08241.7 EKG18751.1 - 0.0024 18.2 0.0 0.0068 16.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain DLH PF01738.13 EKG18751.1 - 0.0027 17.0 0.0 1.6 7.9 0.0 2.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Methyltransf_25 PF13649.1 EKG18751.1 - 0.044 14.1 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Abhydrolase_1 PF00561.15 EKG18751.1 - 0.12 11.9 0.8 0.46 10.0 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold PP-binding_2 PF14573.1 EKG18751.1 - 0.21 11.6 0.1 0.82 9.7 0.0 2.0 2 0 0 2 2 1 0 Acyl-carrier COesterase PF00135.23 EKG18751.1 - 0.25 10.0 0.0 0.42 9.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family PhoPQ_related PF10142.4 EKG18751.1 - 0.27 9.6 0.0 0.52 8.7 0.0 1.4 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 EKG18751.1 - 0.43 9.0 0.0 1.5 7.2 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.23 EKG18752.1 - 1.5e-75 254.2 0.0 2.2e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EKG18752.1 - 7e-29 100.6 0.0 1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EKG18752.1 - 1.9e-11 44.0 0.0 6.7e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG18752.1 - 8.2e-05 23.4 0.0 0.0014 19.5 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glyco_hydro_43 PF04616.9 EKG18753.1 - 5.2e-53 179.9 1.1 7.2e-53 179.5 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RTA1 PF04479.8 EKG18754.1 - 3e-14 53.0 0.9 3.4e-14 52.8 0.6 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF4328 PF14219.1 EKG18754.1 - 0.57 9.4 3.6 0.78 9.0 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4328) ATP13 PF12921.2 EKG18757.1 - 1.4e-26 92.2 0.0 5.3e-26 90.4 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression PPR_3 PF13812.1 EKG18757.1 - 0.00046 20.2 0.1 1.7 9.1 0.0 4.0 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EKG18757.1 - 0.001 19.0 0.0 0.073 13.0 0.0 2.8 2 0 0 2 2 2 1 PPR repeat family ABC_tran PF00005.22 EKG18758.1 - 8.8e-49 165.3 0.1 3.7e-26 92.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EKG18758.1 - 2.4e-26 92.6 54.5 3.6e-17 62.4 23.0 2.4 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EKG18758.1 - 1.6e-22 80.8 0.2 1.3e-05 25.3 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EKG18758.1 - 1.4e-10 40.4 2.0 3.8e-05 23.1 0.5 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EKG18758.1 - 6.1e-09 35.4 0.0 0.047 12.9 0.2 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKG18758.1 - 1.2e-06 29.0 4.6 0.008 16.5 0.4 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKG18758.1 - 4.4e-06 26.8 0.7 0.04 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EKG18758.1 - 2.4e-05 23.5 0.2 0.11 11.6 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EKG18758.1 - 0.00048 19.2 0.0 0.16 10.9 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EKG18758.1 - 0.00058 19.3 0.3 0.44 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKG18758.1 - 0.022 14.8 0.1 5.5 7.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain MutS_V PF00488.16 EKG18758.1 - 0.027 13.8 0.3 0.91 8.8 0.0 2.8 4 0 0 4 4 3 0 MutS domain V AAA_28 PF13521.1 EKG18758.1 - 0.028 14.3 0.7 4.6 7.1 0.4 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKG18758.1 - 0.042 13.7 0.1 17 5.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EKG18758.1 - 0.058 12.8 0.8 9.3 5.5 0.4 2.4 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 EKG18758.1 - 0.092 11.8 0.1 14 4.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 EKG18758.1 - 0.14 11.5 0.8 14 5.0 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EKG18758.1 - 0.21 11.3 7.6 1.2 8.9 0.1 3.8 4 0 0 4 4 3 0 Part of AAA domain Miro PF08477.8 EKG18758.1 - 0.23 11.9 0.5 41 4.7 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein K1377 PF15352.1 EKG18758.1 - 0.57 8.0 0.1 0.82 7.5 0.0 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy AAA_13 PF13166.1 EKG18758.1 - 0.61 8.4 0.2 20 3.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain NmrA PF05368.8 EKG18759.1 - 1.1e-07 31.3 0.0 2.5e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG18759.1 - 6.1e-07 29.6 0.0 1.6e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding DUF3335 PF11814.3 EKG18759.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Methyltransf_23 PF13489.1 EKG18760.1 - 8.1e-20 71.1 0.0 9.2e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18760.1 - 6.8e-10 39.5 0.0 1.5e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18760.1 - 8.6e-08 32.5 0.0 6.1e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18760.1 - 5e-07 29.4 0.0 9.9e-06 25.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18760.1 - 1.5e-06 28.5 0.0 2.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EKG18760.1 - 0.0035 16.8 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EKG18760.1 - 0.004 17.1 0.0 0.0094 15.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EKG18760.1 - 0.0059 16.0 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EKG18760.1 - 0.0087 15.6 0.0 0.19 11.2 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EKG18760.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EKG18760.1 - 0.022 13.9 0.0 0.18 10.9 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EKG18760.1 - 0.041 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EKG18760.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EKG18760.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_M43 PF05572.8 EKG18762.1 - 3.5e-14 52.6 0.1 6.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EKG18762.1 - 0.0012 18.8 2.1 0.01 15.7 1.5 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EKG18762.1 - 0.01 15.3 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EKG18762.1 - 0.017 15.1 5.3 0.058 13.4 3.7 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EKG18762.1 - 0.089 13.3 1.7 0.19 12.2 1.1 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EKG18762.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 EKG18762.1 - 0.3 9.9 4.3 0.58 8.9 3.0 1.4 1 0 0 1 1 1 0 Peptidase M66 SdpI PF13630.1 EKG18764.1 - 0.017 14.8 3.0 0.039 13.6 2.1 1.6 1 0 0 1 1 1 0 SdpI/YhfL protein family PHO4 PF01384.15 EKG18764.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family Methyltransf_23 PF13489.1 EKG18768.1 - 2.9e-22 79.1 0.0 5.4e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18768.1 - 1.1e-08 35.6 0.1 1.7e-07 31.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18768.1 - 9.1e-07 29.2 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18768.1 - 1.2e-06 28.2 0.0 2.9e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18768.1 - 4.3e-05 23.9 0.0 0.00046 20.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG18768.1 - 0.00073 19.8 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG18768.1 - 0.00085 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EKG18768.1 - 0.0028 17.6 0.0 0.017 15.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG18768.1 - 0.035 13.2 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EKG18768.1 - 0.037 13.1 0.0 0.54 9.3 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Fungal_trans_2 PF11951.3 EKG18769.1 - 1.5e-06 27.0 0.0 2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG18769.1 - 3.3e-06 26.8 11.7 6.4e-06 25.9 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PMG PF05287.7 EKG18770.1 - 0.24 11.1 4.8 0.34 10.6 3.3 1.1 1 0 0 1 1 1 0 PMG protein ORC6 PF05460.8 EKG18770.1 - 0.84 8.6 3.8 1.2 8.2 2.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Abhydrolase_3 PF07859.8 EKG18772.1 - 7.4e-15 55.0 0.0 4.4e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG18772.1 - 2.9e-11 42.9 0.0 1.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.7 EKG18772.1 - 2.5e-09 36.1 0.0 0.00074 18.1 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.2 EKG18772.1 - 7.6e-09 35.4 0.0 1.6e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG18772.1 - 4.1e-06 26.8 1.2 7.8e-06 25.9 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EKG18772.1 - 2.2e-05 23.3 0.0 0.00043 19.1 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase Chlorophyllase2 PF12740.2 EKG18772.1 - 7.8e-05 21.6 0.0 0.00023 20.1 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme COesterase PF00135.23 EKG18772.1 - 9.5e-05 21.2 0.0 0.0014 17.4 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EKG18772.1 - 0.0013 18.2 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EKG18772.1 - 0.015 14.7 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 EKG18772.1 - 0.04 13.1 0.2 0.61 9.2 0.0 2.5 3 0 0 3 3 3 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.15 EKG18772.1 - 0.046 13.2 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.9 EKG18772.1 - 0.064 12.4 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase Glyco_trans_4_4 PF13579.1 EKG18772.1 - 0.095 12.8 2.5 0.39 10.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Esterase PF00756.15 EKG18772.1 - 0.13 11.6 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Putative esterase DUF4117 PF13491.1 EKG18773.1 - 0.01 15.2 4.2 0.034 13.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) DUF3583 PF12126.3 EKG18773.1 - 0.045 12.8 0.0 0.06 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) PRRSV_2b PF07069.6 EKG18773.1 - 7.7 6.8 10.7 3.2 8.1 0.8 3.0 1 1 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b Asp PF00026.18 EKG18776.1 - 3.7e-10 39.5 0.1 5.7e-10 38.9 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EKG18776.1 - 0.0021 17.6 0.1 0.0057 16.2 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Syndecan PF01034.15 EKG18776.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain MFS_1 PF07690.11 EKG18779.1 - 3.5e-21 75.2 34.9 7.3e-21 74.2 19.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG18779.1 - 0.007 14.9 33.9 0.034 12.7 22.0 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3098 PF11297.3 EKG18779.1 - 0.39 10.4 6.0 0.66 9.7 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3098) F-box PF00646.28 EKG18781.1 - 0.045 13.4 0.0 0.17 11.5 0.0 2.0 2 1 0 2 2 2 0 F-box domain PLU-1 PF08429.6 EKG18783.1 - 5.7e-94 314.7 13.1 1.3e-91 307.0 9.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EKG18783.1 - 1.7e-44 150.7 0.4 4.5e-44 149.3 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EKG18783.1 - 1e-26 92.5 0.0 2.6e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EKG18783.1 - 9.7e-19 66.8 27.2 3.4e-10 39.4 3.3 3.5 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.11 EKG18783.1 - 4.7e-16 58.5 4.2 1.1e-15 57.3 2.9 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 EKG18783.1 - 1.9e-15 56.0 2.2 4.8e-15 54.7 1.5 1.8 1 0 0 1 1 1 1 jmjN domain Prok-RING_1 PF14446.1 EKG18783.1 - 6.7e-05 22.5 1.9 6.7e-05 22.5 1.3 3.6 3 0 0 3 3 3 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.1 EKG18783.1 - 0.023 14.0 6.7 0.34 10.1 0.4 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EKG18783.1 - 0.024 14.3 14.6 0.28 10.9 0.1 3.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EKG18783.1 - 9.6 5.6 15.9 0.036 13.3 0.7 3.1 3 0 0 3 3 3 0 PHD-finger GIY-YIG PF01541.19 EKG18784.1 - 1.1e-10 41.7 0.0 2.7e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EKG18784.1 - 9.6e-07 28.6 4.6 1.7e-06 27.8 3.2 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EKG18784.1 - 0.00052 20.1 3.3 0.001 19.1 2.3 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD PF00628.24 EKG18784.1 - 0.0013 18.3 4.6 0.0022 17.6 3.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 EKG18784.1 - 0.0039 17.1 2.8 0.0081 16.1 2.0 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_2 PF13639.1 EKG18784.1 - 0.0099 15.6 4.3 0.017 14.9 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 EKG18784.1 - 0.064 13.2 4.5 0.29 11.1 3.1 2.1 1 1 0 1 1 1 0 RING-like domain Vps39_2 PF10367.4 EKG18784.1 - 0.067 13.3 3.2 0.058 13.5 0.9 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Prok-RING_1 PF14446.1 EKG18784.1 - 0.16 11.7 6.9 0.057 13.1 1.8 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EKG18784.1 - 1.2 9.2 4.8 2.2 8.4 3.3 1.5 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EKG18784.1 - 1.2 8.9 4.4 1.1 8.9 1.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Thymidylate_kin PF02223.12 EKG18785.1 - 1.2e-44 151.9 0.0 1.4e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EKG18785.1 - 8.6e-05 22.5 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EKG18785.1 - 0.0071 15.5 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EKG18785.1 - 0.0078 16.1 0.0 0.02 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EKG18785.1 - 0.084 11.9 0.0 9.3 5.2 0.0 2.1 2 0 0 2 2 2 0 ATPase MipZ SRP54 PF00448.17 EKG18785.1 - 0.094 12.1 0.4 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF1115 PF06544.7 EKG18786.1 - 0.089 12.4 0.0 0.25 11.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1115) SGS PF05002.10 EKG18787.1 - 2.5e-32 110.4 2.3 5.9e-32 109.2 1.6 1.7 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EKG18787.1 - 7.1e-20 71.3 0.2 1.3e-19 70.5 0.1 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EKG18787.1 - 1.8e-09 37.1 7.9 5.7e-09 35.4 1.1 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EKG18787.1 - 3.6e-06 26.3 6.2 0.00022 20.6 0.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG18787.1 - 6.4e-05 23.5 5.7 6.4e-05 23.5 3.9 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG18787.1 - 0.00048 19.8 15.9 0.00085 19.0 1.4 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG18787.1 - 0.0029 18.1 1.2 0.0029 18.1 0.8 3.6 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG18787.1 - 0.0087 15.7 2.4 0.61 9.9 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG18787.1 - 0.0099 16.2 5.8 0.13 12.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG18787.1 - 0.22 12.0 9.8 0.13 12.7 0.9 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EKG18787.1 - 0.94 9.4 3.7 0.76 9.7 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EKG18787.1 - 8.5 6.3 9.5 9.5 6.2 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4243 PF14027.1 EKG18788.1 - 1.5e-96 323.6 1.1 2e-96 323.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Aminotran_1_2 PF00155.16 EKG18790.1 - 5.1e-11 42.1 0.0 2.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II LCCL PF03815.14 EKG18791.1 - 1.1e-21 76.6 0.3 2e-21 75.7 0.2 1.5 1 1 0 1 1 1 1 LCCL domain DUF4401 PF14351.1 EKG18791.1 - 0.024 13.6 14.0 0.02 13.9 7.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) Peptidase_S8 PF00082.17 EKG18794.1 - 1.6e-36 125.8 2.6 1.9e-36 125.7 0.2 2.2 2 0 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 EKG18794.1 - 8.3e-09 35.8 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EKG18794.1 - 5.4e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 PA domain FAT PF02259.18 EKG18797.1 - 2.1e-73 247.3 10.4 2.1e-73 247.3 7.2 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EKG18797.1 - 3.2e-28 98.7 0.0 1.1e-27 97.0 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EKG18797.1 - 1.8e-06 27.2 0.1 4.7e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EKG18797.1 - 0.0014 18.5 0.2 1.2 9.3 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat TPR_2 PF07719.12 EKG18797.1 - 0.17 11.9 5.1 5.4 7.1 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Rtf2 PF04641.7 EKG18797.1 - 0.52 9.4 5.5 1 8.4 3.8 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger TPR_8 PF13181.1 EKG18797.1 - 0.95 9.3 5.4 7.2 6.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat EXS PF03124.9 EKG18798.1 - 2.4e-92 309.6 29.5 3e-92 309.3 20.4 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EKG18798.1 - 4.9e-42 144.6 1.7 4.9e-42 144.6 1.2 2.1 2 0 0 2 2 2 1 SPX domain DUF3759 PF12585.3 EKG18799.1 - 1.8e-39 133.5 9.9 2.1e-39 133.2 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.2 EKG18799.1 - 6.5 7.6 7.3 3.7 8.4 2.6 2.0 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Abhydrolase_2 PF02230.11 EKG18800.1 - 1.1e-17 64.1 0.0 1.3e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EKG18800.1 - 6.2e-09 36.0 0.7 1e-08 35.3 0.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG18800.1 - 3.6e-07 30.0 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG18800.1 - 0.088 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short_C2 PF13561.1 EKG18802.1 - 2.5e-25 89.6 0.1 3.1e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG18802.1 - 5.9e-20 71.8 0.3 9.2e-20 71.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG18802.1 - 2.1e-06 27.5 1.0 1.2e-05 25.0 0.7 1.9 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EKG18802.1 - 0.0047 16.0 0.2 0.0095 15.0 0.1 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EKG18802.1 - 0.0052 17.1 0.8 0.01 16.2 0.6 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EKG18802.1 - 0.031 14.0 0.2 0.07 12.8 0.2 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EKG18802.1 - 0.033 13.8 1.3 0.078 12.6 0.9 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3698 PF12479.3 EKG18802.1 - 0.042 13.9 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Prenyltrans_1 PF13243.1 EKG18804.1 - 5.7e-28 97.1 0.8 1.6e-12 47.3 0.4 6.3 5 2 1 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 EKG18804.1 - 2.2e-27 94.2 11.8 1.5e-09 37.2 0.0 5.8 7 0 0 7 7 7 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EKG18804.1 - 1.9e-23 83.0 2.0 3e-12 46.9 0.2 5.3 3 1 2 5 5 5 4 Prenyltransferase-like p450 PF00067.17 EKG18805.1 - 6.8e-30 103.9 0.0 9.7e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_jaz PF12171.3 EKG18806.1 - 0.043 13.9 23.2 0.072 13.2 0.7 5.0 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF1318 PF07027.7 EKG18806.1 - 0.14 12.4 0.3 0.14 12.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) zf-LYAR PF08790.6 EKG18806.1 - 0.83 9.4 11.8 5.1 6.8 0.2 4.5 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 EKG18806.1 - 3.4 8.2 34.0 0.076 13.3 0.9 5.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EKG18806.1 - 8.8 6.1 13.4 15 5.3 0.7 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type NUDIX PF00293.23 EKG18808.1 - 3.5e-15 55.8 0.1 6.2e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EKG18808.1 - 1.7e-14 53.8 0.1 1.4e-13 50.9 0.0 2.2 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EKG18808.1 - 8.8e-05 21.9 2.2 0.00018 20.9 1.6 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain F-box PF00646.28 EKG18809.1 - 0.0051 16.4 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKG18809.1 - 0.0076 15.9 1.2 0.015 15.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like DUF2360 PF10152.4 EKG18809.1 - 8.8 6.6 7.4 17 5.6 5.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Ecm33 PF12454.3 EKG18810.1 - 0.0045 16.8 0.3 0.0082 15.9 0.2 1.4 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EKG18810.1 - 0.012 15.5 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 Receptor L domain TarH PF02203.10 EKG18811.1 - 0.19 11.5 0.1 0.19 11.5 0.1 2.6 3 0 0 3 3 3 0 Tar ligand binding domain homologue DUF2393 PF09624.5 EKG18811.1 - 1 8.9 3.4 0.55 9.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) PDR_CDR PF06422.7 EKG18811.1 - 1.2 8.8 5.6 3.1 7.5 0.4 3.3 3 0 0 3 3 3 0 CDR ABC transporter Pkinase PF00069.20 EKG18814.1 - 8.9e-72 241.3 0.0 1.4e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG18814.1 - 1.4e-35 122.6 0.0 2.4e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG18814.1 - 0.00017 20.6 0.1 0.0017 17.3 0.0 2.1 1 1 0 2 2 2 1 Kinase-like GTP_cyclohydroI PF01227.17 EKG18815.1 - 2.2e-73 245.3 0.3 3.1e-73 244.8 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EKG18815.1 - 0.0016 18.3 0.0 0.0041 17.0 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein UPF0047 PF01894.12 EKG18817.1 - 1.3e-39 134.6 0.0 1.5e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Drf_FH1 PF06346.7 EKG18817.1 - 0.023 14.2 8.1 0.033 13.6 5.6 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 p450 PF00067.17 EKG18820.1 - 4.1e-05 22.2 0.0 4.9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Kelch_5 PF13854.1 EKG18821.1 - 1.1e-09 37.9 0.8 2.5e-05 24.0 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EKG18821.1 - 7.4e-05 22.4 6.3 0.32 10.8 0.1 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EKG18821.1 - 0.007 16.5 11.5 0.0088 16.1 0.2 4.0 5 0 0 5 5 5 2 Galactose oxidase, central domain COesterase PF00135.23 EKG18823.1 - 6.2e-70 236.4 0.2 8.2e-70 236.0 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG18823.1 - 0.00028 20.5 1.2 0.0029 17.2 0.5 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG18823.1 - 0.0016 17.7 0.3 0.0037 16.5 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG18823.1 - 0.011 15.5 0.2 0.022 14.4 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG18823.1 - 0.027 14.3 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.5 EKG18823.1 - 0.051 12.4 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) SnoaL_2 PF12680.2 EKG18825.1 - 2.2e-13 50.4 0.2 2.6e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EKG18825.1 - 0.00037 20.4 0.1 0.00042 20.2 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EKG18825.1 - 0.0004 19.9 0.1 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 EKG18825.1 - 0.00044 20.4 0.3 0.00067 19.8 0.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.1 EKG18825.1 - 0.002 18.1 0.2 0.0025 17.8 0.1 1.3 1 1 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.15 EKG18825.1 - 0.096 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DHHA2 PF02833.9 EKG18827.1 - 6.7e-26 90.9 0.0 1.6e-25 89.7 0.0 1.6 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.15 EKG18827.1 - 8.5e-10 38.4 0.0 1.8e-09 37.3 0.0 1.6 1 1 0 1 1 1 1 DHH family RasGAP PF00616.14 EKG18828.1 - 0.042 13.4 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase DUF905 PF06006.7 EKG18829.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Methyltransf_32 PF13679.1 EKG18830.1 - 1e-20 73.8 3.3 2.6e-10 40.1 0.1 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18830.1 - 0.028 13.9 0.1 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18830.1 - 0.054 14.0 0.0 0.19 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PhoD PF09423.5 EKG18831.1 - 2.2e-64 217.7 0.0 3e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Glyco_hydro_32N PF00251.15 EKG18834.1 - 2.1e-77 260.5 5.4 2.7e-77 260.1 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EKG18834.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 C terminal Methyltransf_23 PF13489.1 EKG18835.1 - 3.7e-22 78.7 0.0 5.9e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG18835.1 - 3.3e-10 40.3 0.0 6.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG18835.1 - 1.1e-09 38.0 0.0 3.8e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG18835.1 - 7e-08 33.0 0.0 2e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG18835.1 - 2.4e-07 31.1 0.0 9e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG18835.1 - 6.4e-05 23.2 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG18835.1 - 0.00058 19.0 0.0 0.0026 16.9 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EKG18835.1 - 0.0017 17.4 0.0 0.031 13.3 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.8 EKG18835.1 - 0.026 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EKG18835.1 - 0.039 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EKG18835.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EKG18835.1 - 0.11 11.8 0.0 0.3 10.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EKG18836.1 - 1.6e-36 125.7 0.0 2.1e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EKG18836.1 - 2.6e-05 24.7 0.0 5.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EKG18836.1 - 0.081 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Cnd3 PF12719.2 EKG18838.1 - 1.1e-89 300.4 0.5 5.1e-88 294.9 0.1 2.6 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EKG18838.1 - 3e-09 37.0 8.6 7.4e-06 26.1 1.4 4.8 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EKG18838.1 - 7.9e-05 22.4 10.8 0.093 12.8 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat DUF1546 PF07571.8 EKG18838.1 - 0.033 14.2 0.3 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EKG18838.1 - 9.7 6.8 12.2 3.1 8.4 0.1 4.9 2 1 3 5 5 5 0 HEAT-like repeat PALP PF00291.20 EKG18839.1 - 9.3e-60 202.4 0.1 1.2e-59 202.0 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pertussis_S2S3 PF02918.10 EKG18840.1 - 0.017 14.8 0.1 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Pertussis toxin, subunit 2 and 3, C-terminal domain ADH_zinc_N PF00107.21 EKG18841.1 - 7.7e-06 25.4 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG18841.1 - 0.046 14.6 0.0 0.12 13.2 0.0 1.7 1 1 1 2 2 2 0 Zinc-binding dehydrogenase AMP-binding PF00501.23 EKG18842.1 - 8.9e-54 182.4 0.0 1.3e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EKG18842.1 - 9.3e-27 94.7 0.0 2.8e-26 93.1 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EKG18842.1 - 6.3e-06 26.3 0.1 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EKG18842.1 - 0.0086 15.9 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Picorna_P3A PF06363.6 EKG18842.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein DAHP_synth_1 PF00793.15 EKG18843.1 - 5.1e-90 300.8 0.0 5.8e-90 300.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Chorismate_synt PF01264.16 EKG18844.1 - 6.5e-69 232.0 0.0 8.5e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase EPSP_synthase PF00275.15 EKG18845.1 - 8e-123 409.9 0.0 1.2e-122 409.4 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EKG18845.1 - 2.5e-103 344.5 0.1 7e-103 343.0 0.0 1.7 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EKG18845.1 - 1.2e-54 185.3 0.0 2e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EKG18845.1 - 2.2e-37 128.3 0.0 5.7e-35 120.5 0.0 3.2 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.6 EKG18845.1 - 7.8e-21 73.9 0.0 1.9e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EKG18845.1 - 4.7e-09 36.4 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EKG18845.1 - 7.1e-09 35.3 0.1 6e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EKG18845.1 - 5.6e-07 30.3 0.0 1.4e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG18845.1 - 0.0013 18.6 0.0 0.019 14.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 EKG18845.1 - 0.45 10.4 0.0 0.93 9.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG18846.1 - 4.5e-06 27.0 0.2 6.6e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EKG18846.1 - 0.0091 15.4 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EKG18846.1 - 0.024 14.1 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EKG18846.1 - 0.031 14.4 0.1 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_trans_N PF14510.1 EKG18846.1 - 0.037 14.0 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal UPF0079 PF02367.12 EKG18846.1 - 0.096 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EKG18846.1 - 0.14 11.0 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3115 PF11312.3 EKG18846.1 - 0.15 10.8 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) AAA_19 PF13245.1 EKG18846.1 - 0.22 11.3 0.8 0.97 9.2 0.0 2.1 1 1 1 2 2 2 0 Part of AAA domain ABC2_membrane PF01061.19 EKG18847.1 - 1.3e-26 93.0 14.1 1.8e-26 92.5 9.8 1.1 1 0 0 1 1 1 1 ABC-2 type transporter AA_synth PF06684.6 EKG18847.1 - 0.038 13.3 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Amino acid synthesis PDR_CDR PF06422.7 EKG18848.1 - 4.4e-24 84.1 0.1 6.2e-24 83.6 0.1 1.2 1 0 0 1 1 1 1 CDR ABC transporter DUF2555 PF10742.4 EKG18848.1 - 0.036 13.6 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) UL2 PF08196.6 EKG18848.1 - 0.064 12.9 0.5 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 UL2 protein Gag_p6 PF08705.6 EKG18848.1 - 0.07 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Gag protein p6 ABC2_membrane PF01061.19 EKG18849.1 - 1.9e-32 112.1 15.6 2.3e-32 111.8 10.8 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 EKG18849.1 - 2.8e-07 29.9 8.0 4.2e-07 29.3 5.5 1.3 1 1 0 1 1 1 1 ABC-2 family transporter protein SbcCD_C PF13558.1 EKG18849.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Fungal_trans PF04082.13 EKG18850.1 - 4.5e-14 51.9 0.0 8.5e-14 51.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PRiA4_ORF3 PF07929.6 EKG18851.1 - 3.1e-11 43.0 0.0 2e-10 40.3 0.0 2.3 1 1 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein Glyoxalase PF00903.20 EKG18852.1 - 2.1e-11 43.8 8.2 4.4e-09 36.3 1.9 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EKG18852.1 - 0.00032 21.2 2.8 0.19 12.3 0.3 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EKG18852.1 - 0.04 13.9 0.4 0.21 11.5 0.1 2.2 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SAYSvFN PF10260.4 EKG18853.1 - 1.8e-16 59.6 0.1 2.2e-16 59.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SPC22 PF04573.7 EKG18854.1 - 8.8e-35 119.4 0.0 5.4e-25 87.6 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit AMP-binding PF00501.23 EKG18856.1 - 0 1118.1 0.0 2.4e-86 289.7 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EKG18856.1 - 9e-263 868.6 0.0 5.3e-51 173.2 0.0 6.4 6 0 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EKG18856.1 - 7.8e-47 157.4 0.1 2.5e-10 40.4 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG18856.1 - 2.8e-25 89.0 1.1 1.4e-06 29.1 0.0 5.0 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EKG18856.1 - 9.9e-06 25.7 2.2 2.5 8.4 0.0 4.6 4 0 0 4 4 4 2 HxxPF-repeated domain Transferase PF02458.10 EKG18856.1 - 0.0027 16.2 0.0 0.56 8.5 0.0 3.7 4 0 0 4 4 4 1 Transferase family ASC PF00858.19 EKG18856.1 - 7.5 5.0 0.5 13 4.2 0.0 1.5 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel ketoacyl-synt PF00109.21 EKG18857.1 - 2.4e-22 79.6 0.7 3.9e-22 78.9 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EKG18857.1 - 4.2e-19 69.2 0.0 6.2e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EKG18857.1 - 3.9e-06 26.7 0.0 8.9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EKG18857.1 - 1.3e-05 25.2 0.0 2.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 EKG18857.1 - 0.047 12.6 0.0 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EKG18857.1 - 0.081 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Aminotran_4 PF01063.14 EKG18858.1 - 7.6e-24 84.4 0.0 1e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV MFS_1 PF07690.11 EKG18859.1 - 1.9e-38 132.0 50.1 1.9e-38 132.0 34.7 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG18859.1 - 2.5e-07 29.2 22.0 3.9e-07 28.6 15.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EKG18860.1 - 1.2e-64 218.5 0.0 1.5e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2171 PF09939.4 EKG18860.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) Acyl_transf_1 PF00698.16 EKG18861.1 - 4.6e-53 180.6 0.0 2.6e-52 178.1 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EKG18861.1 - 1e-29 102.4 0.0 2.4e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EKG18861.1 - 8.2e-27 92.7 0.6 2.1e-26 91.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EKG18861.1 - 4.4e-16 58.8 0.0 1.7e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EKG18861.1 - 0.00083 18.5 0.1 0.0062 15.7 0.1 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase Cytokin-bind PF09265.5 EKG18861.1 - 0.25 10.4 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Dynein_heavy PF03028.10 EKG18861.1 - 0.41 8.6 0.0 0.62 8.0 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor RNase_H PF00075.19 EKG18864.1 - 1.8e-15 57.4 0.0 2.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EKG18864.1 - 0.0003 20.5 0.1 0.0078 15.9 0.0 2.8 3 0 0 3 3 3 1 Reverse transcriptase-like Pyr_redox_3 PF13738.1 EKG18865.1 - 4.2e-22 79.2 0.1 1.4e-21 77.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG18865.1 - 1e-11 45.1 0.0 1.5e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG18865.1 - 5.3e-10 38.1 0.2 2.4e-08 32.6 0.1 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 EKG18865.1 - 6e-07 28.6 0.8 6e-06 25.3 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG18865.1 - 2.7e-06 27.3 0.2 9.6e-06 25.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EKG18865.1 - 4.7e-06 25.7 0.2 0.0026 16.7 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EKG18865.1 - 8.9e-06 24.9 0.2 1.6e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EKG18865.1 - 0.00011 20.8 0.2 0.014 13.9 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 EKG18865.1 - 0.00036 19.6 0.5 0.0028 16.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EKG18865.1 - 0.0005 19.0 0.8 0.0031 16.4 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EKG18865.1 - 0.0011 19.2 0.5 0.1 13.0 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG18865.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG18865.1 - 0.0034 16.3 0.0 0.015 14.2 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EKG18865.1 - 0.0054 16.3 0.1 0.013 15.1 0.0 1.6 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EKG18865.1 - 0.0098 15.6 0.4 0.42 10.3 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EKG18865.1 - 0.022 13.6 0.1 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EKG18865.1 - 0.043 13.9 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EKG18865.1 - 0.061 11.9 1.0 1.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.14 EKG18865.1 - 0.16 11.1 0.0 0.45 9.6 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PfkB PF00294.19 EKG18866.1 - 5.2e-48 163.7 5.3 1.6e-25 89.8 0.6 2.0 1 1 1 2 2 2 2 pfkB family carbohydrate kinase Peptidase_M16_C PF05193.16 EKG18867.1 - 1.1e-34 119.7 0.0 1e-21 77.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EKG18867.1 - 1.4e-33 115.7 3.2 9e-33 113.1 1.7 2.8 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) EthD PF07110.6 EKG18868.1 - 8.9e-18 65.0 1.4 1.1e-17 64.6 1.0 1.1 1 0 0 1 1 1 1 EthD domain Acyl-CoA_dh_1 PF00441.19 EKG18869.1 - 2.8e-29 102.1 0.9 4.2e-29 101.5 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EKG18869.1 - 3.7e-19 67.9 0.4 6.7e-19 67.1 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EKG18869.1 - 1.8e-17 63.9 0.0 6e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EKG18869.1 - 6.7e-08 32.8 0.3 1.1e-07 32.1 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mso1_C PF14477.1 EKG18869.1 - 0.079 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Membrane-polarising domain of Mso1 Cellulase PF00150.13 EKG18870.1 - 3.2e-15 56.0 2.8 5.3e-15 55.3 2.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EKG18870.1 - 0.0047 16.3 0.2 0.0078 15.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Bclx_interact PF08945.5 EKG18870.1 - 0.048 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain LURAP PF14854.1 EKG18872.1 - 0.052 13.2 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein polyprenyl_synt PF00348.12 EKG18873.1 - 1.5e-74 250.1 0.0 1.8e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Homeobox PF00046.24 EKG18873.1 - 0.37 10.4 2.7 0.93 9.1 0.1 2.6 3 0 0 3 3 3 0 Homeobox domain APC8 PF04049.8 EKG18874.1 - 3.7e-30 104.5 0.0 2.3e-29 101.9 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EKG18874.1 - 1.3e-21 75.1 11.5 3e-06 26.5 0.4 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG18874.1 - 8.2e-19 67.0 14.8 5.7e-11 41.8 0.2 6.0 4 1 2 6 6 6 4 TPR repeat TPR_8 PF13181.1 EKG18874.1 - 1.2e-16 59.1 12.9 0.00074 19.1 0.0 7.0 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EKG18874.1 - 2.7e-16 58.0 21.3 0.00017 21.2 0.8 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EKG18874.1 - 1.8e-13 49.8 12.0 0.011 16.2 0.0 8.7 6 1 3 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EKG18874.1 - 1.5e-09 37.6 16.9 8.3e-05 22.4 0.8 6.4 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EKG18874.1 - 6.1e-08 33.1 21.3 5.3e-05 23.7 0.0 6.2 7 1 1 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG18874.1 - 9.9e-07 28.8 10.6 0.015 15.4 0.9 5.1 4 1 2 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EKG18874.1 - 5.2e-06 26.7 1.6 0.01 16.1 0.0 5.3 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKG18874.1 - 0.00018 21.4 6.0 0.69 10.2 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EKG18874.1 - 0.00029 20.0 0.9 0.00029 20.0 0.6 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKG18874.1 - 0.00049 19.6 11.7 3.8 7.5 0.0 6.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG18874.1 - 0.0016 18.2 9.9 0.7 9.7 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKG18874.1 - 0.0016 18.7 23.1 0.68 10.5 0.5 7.5 9 0 0 9 9 8 1 Tetratricopeptide repeat ChAPs PF09295.5 EKG18874.1 - 0.0099 14.6 0.3 0.31 9.7 0.0 2.3 1 1 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF3856 PF12968.2 EKG18874.1 - 0.042 13.6 1.0 0.37 10.6 0.0 2.8 2 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 EKG18874.1 - 0.13 12.1 3.5 17 5.3 0.1 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EKG18874.1 - 4.4 7.3 10.5 13 5.9 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 EKG18875.1 - 6.1e-17 61.9 0.1 3.7e-07 29.9 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_M15_4 PF13539.1 EKG18875.1 - 0.049 14.0 0.0 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Amidinotransf PF02274.12 EKG18875.1 - 0.16 11.0 0.0 0.35 9.9 0.0 1.5 2 0 0 2 2 2 0 Amidinotransferase Pyr_redox_3 PF13738.1 EKG18876.1 - 2.7e-24 86.3 0.0 3.8e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG18876.1 - 9.4e-16 57.0 0.0 3.1e-13 48.7 0.0 2.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG18876.1 - 8.6e-11 41.7 0.0 5.6e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG18876.1 - 7.7e-07 28.4 0.0 6.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EKG18876.1 - 2.4e-05 23.4 0.7 0.00025 20.0 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG18876.1 - 0.00013 21.8 0.0 0.00056 19.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG18876.1 - 0.00028 19.9 0.0 0.019 13.9 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EKG18876.1 - 0.001 19.4 0.3 0.18 12.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG18876.1 - 0.0026 17.8 0.0 0.41 10.7 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EKG18876.1 - 0.0037 16.1 0.0 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain PTS_IIB PF02302.12 EKG18876.1 - 0.017 15.5 0.1 0.58 10.6 0.0 2.4 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit NAD_binding_7 PF13241.1 EKG18876.1 - 0.019 15.2 0.0 0.42 10.8 0.0 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EKG18876.1 - 0.074 12.8 0.5 2.9 7.6 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding BRCT PF00533.21 EKG18877.1 - 1.2e-06 28.5 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AIG2 PF06094.7 EKG18878.1 - 1.6e-10 41.3 0.0 2.8e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family DUF4436 PF14494.1 EKG18878.1 - 0.071 12.3 0.5 5.3 6.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4436) PSD3 PF07626.6 EKG18878.1 - 0.11 12.5 0.3 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) PQ-loop PF04193.9 EKG18879.1 - 2.5e-15 55.7 1.7 2.9e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 PQ loop repeat Nop10p PF04135.7 EKG18881.1 - 9e-22 76.5 0.1 1.2e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family NOB1_Zn_bind PF08772.6 EKG18882.1 - 2.5e-30 104.1 4.4 4.4e-30 103.3 3.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EKG18882.1 - 1.1e-05 25.2 0.6 2.9e-05 23.8 0.4 1.7 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EKG18882.1 - 0.07 12.6 3.8 0.048 13.1 0.7 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RRP7 PF12923.2 EKG18882.1 - 0.42 10.6 2.9 0.29 11.1 0.3 1.9 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) TFIIA PF03153.8 EKG18882.1 - 8.5 6.1 14.1 13 5.5 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C48 PF02902.14 EKG18885.1 - 4.6e-30 104.8 0.1 2e-29 102.7 0.1 1.9 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 EKG18887.1 - 1.5e-51 174.1 0.3 2.4e-51 173.5 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IPP-2 PF04979.9 EKG18888.1 - 6.3e-11 42.6 15.6 1.8e-06 28.2 1.2 2.2 1 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF2346 PF09803.4 EKG18888.1 - 0.19 11.5 2.0 0.4 10.5 1.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) bZIP_1 PF00170.16 EKG18889.1 - 1.9e-08 34.1 14.7 2.3e-05 24.2 4.6 2.6 2 0 0 2 2 2 2 bZIP transcription factor Hap4_Hap_bind PF10297.4 EKG18889.1 - 4e-05 23.3 5.2 0.00013 21.7 3.6 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 EKG18889.1 - 0.0035 17.1 18.8 0.11 12.3 6.2 2.7 2 0 0 2 2 2 2 Basic region leucine zipper DUF4559 PF15112.1 EKG18889.1 - 0.1 11.7 4.5 0.22 10.6 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Zwint PF15556.1 EKG18889.1 - 0.3 10.3 16.2 0.077 12.2 9.1 1.5 2 0 0 2 2 2 0 ZW10 interactor Cep57_CLD_2 PF14197.1 EKG18889.1 - 0.3 11.0 14.3 0.37 10.7 7.9 2.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Dehalogenase PF13486.1 EKG18889.1 - 0.45 9.9 4.0 0.89 8.9 2.8 1.4 1 0 0 1 1 1 0 Reductive dehalogenase subunit Phlebovirus_NSM PF07246.6 EKG18889.1 - 1.3 8.1 4.7 2.1 7.4 3.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PEARLI-4 PF05278.7 EKG18889.1 - 3.2 7.0 8.3 5.6 6.2 5.8 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4407 PF14362.1 EKG18889.1 - 3.6 6.4 7.0 6.9 5.5 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 EKG18889.1 - 4.6 6.8 13.5 1.5 8.4 7.0 1.8 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 EKG18889.1 - 9.4 5.7 12.7 19 4.7 8.8 1.5 1 0 0 1 1 1 0 IncA protein BAR_3_WASP_bdg PF10456.4 EKG18890.1 - 0.015 14.5 1.7 0.036 13.3 0.1 2.3 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein GLE1 PF07817.8 EKG18890.1 - 0.12 11.2 0.1 0.25 10.2 0.1 1.4 1 0 0 1 1 1 0 GLE1-like protein FlaC_arch PF05377.6 EKG18890.1 - 0.82 9.6 11.7 9.2 6.2 0.0 5.9 7 1 1 8 8 8 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EKG18890.1 - 2.4 8.2 7.6 30 4.7 0.0 4.0 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EKG18890.1 - 3.3 7.5 9.2 18 5.1 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Nucleoplasmin PF03066.10 EKG18890.1 - 8.4 5.8 14.3 0.45 10.0 1.7 2.8 2 0 0 2 2 2 0 Nucleoplasmin Sdh_cyt PF01127.17 EKG18891.1 - 3e-24 85.1 5.3 3.7e-24 84.8 3.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TRP_2 PF08344.6 EKG18891.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Transient receptor ion channel II WD40 PF00400.27 EKG18892.1 - 8.4e-15 54.0 5.1 6.3e-05 22.6 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EKG18892.1 - 0.076 12.4 0.0 0.94 8.8 0.0 2.2 1 1 1 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.11 EKG18892.1 - 0.099 10.9 0.0 3.4 5.8 0.0 2.4 2 1 0 2 2 2 0 Cytochrome D1 heme domain FRQ PF09421.5 EKG18892.1 - 0.28 8.9 4.0 0.4 8.4 2.8 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF3405 PF11885.3 EKG18894.1 - 9.9e-157 522.1 8.5 9.9e-157 522.1 5.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) Glucosamine_iso PF01182.15 EKG18894.1 - 0.26 10.9 1.9 0.93 9.1 0.1 2.2 2 0 0 2 2 2 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribonucleas_3_3 PF14622.1 EKG18895.1 - 4.4e-26 91.3 0.0 7.5e-26 90.5 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EKG18895.1 - 1.3e-05 25.6 0.0 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain KAT11 PF08214.6 EKG18896.1 - 5.8e-05 22.3 0.0 9.8e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Histone acetylation protein DNA_ligase_A_M PF01068.16 EKG18897.1 - 2.5e-23 82.5 0.0 4.7e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EKG18897.1 - 2e-10 40.7 0.0 4.7e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus Cerato-platanin PF07249.7 EKG18898.1 - 0.034 14.1 0.8 0.074 13.0 0.6 1.7 1 0 0 1 1 1 0 Cerato-platanin NMO PF03060.10 EKG18899.1 - 2.6e-63 214.1 0.2 4.7e-63 213.3 0.1 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EKG18899.1 - 2.9e-10 39.5 0.0 0.00041 19.3 0.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EKG18899.1 - 0.021 13.6 0.1 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 EKG18899.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Glu_synthase PF01645.12 EKG18899.1 - 0.041 12.7 0.2 0.093 11.6 0.2 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase Pyr_redox_2 PF07992.9 EKG18900.1 - 4.7e-10 39.6 0.0 5.5e-09 36.1 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG18900.1 - 2.2e-08 34.3 0.3 0.031 14.6 0.3 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG18900.1 - 1.7e-05 24.9 0.1 0.00099 19.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG18900.1 - 0.00091 18.2 0.1 0.034 13.0 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EKG18900.1 - 0.043 13.5 1.1 18 5.0 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 EKG18900.1 - 0.27 10.1 6.5 8.7 5.1 1.5 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG18900.1 - 0.44 9.4 1.8 6.9 5.4 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein TP6A_N PF04406.9 EKG18901.1 - 3e-18 65.2 0.3 5.9e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 EKG18901.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) CAF1A PF12253.3 EKG18902.1 - 3.1e-24 84.8 7.5 6e-24 83.9 5.2 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A UPF0081 PF03652.10 EKG18902.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) FYDLN_acid PF09538.5 EKG18902.1 - 0.23 12.0 8.1 0.62 10.6 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Glyco_transf_21 PF13506.1 EKG18903.1 - 3.6e-16 58.9 0.0 3.4e-07 29.7 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EKG18903.1 - 2.9e-12 46.8 0.0 5.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Asp PF00026.18 EKG18903.1 - 5.3e-09 35.7 0.0 2.1e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Glycos_transf_2 PF00535.21 EKG18903.1 - 0.01 15.5 0.0 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 HAMP PF00672.20 EKG18903.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 HAMP domain tRNA-synt_1c PF00749.16 EKG18904.1 - 1.4e-104 349.1 0.1 1.9e-104 348.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EKG18904.1 - 4.4e-38 130.6 0.2 7.6e-38 129.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EKG18904.1 - 3.6e-06 27.3 0.1 1.2e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EKG18904.1 - 0.0062 15.6 0.4 0.015 14.4 0.3 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Tau95 PF09734.4 EKG18906.1 - 1.1e-49 169.5 0.3 1.5e-49 169.0 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 EKG18907.1 - 7.8e-174 578.0 6.6 9.5e-174 577.7 4.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Cnd1 PF12717.2 EKG18907.1 - 0.16 11.7 0.8 7 6.4 0.1 2.6 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 SOG2 PF10428.4 EKG18907.1 - 0.47 9.0 4.5 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein ELO PF01151.13 EKG18909.1 - 9.6e-61 205.2 19.7 1.1e-60 205.0 13.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Kelch_5 PF13854.1 EKG18909.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Kelch motif COX5A PF02284.11 EKG18910.1 - 4.1e-39 132.8 0.5 5.7e-39 132.4 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 EKG18910.1 - 0.032 12.6 0.2 0.61 8.3 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 GATase_5 PF13507.1 EKG18911.1 - 1.6e-97 325.4 0.0 2.3e-97 324.9 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EKG18911.1 - 4.6e-45 153.3 0.9 7.8e-23 81.1 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EKG18911.1 - 4.1e-26 91.0 0.0 1.5e-25 89.2 0.0 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Syntaxin-6_N PF09177.6 EKG18912.1 - 1.7e-24 85.9 0.8 4.3e-24 84.7 0.1 1.9 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EKG18912.1 - 1.5e-12 47.0 5.7 4.1e-12 45.6 0.4 3.0 3 0 0 3 3 3 1 SNARE domain PilJ PF13675.1 EKG18912.1 - 0.054 13.8 4.5 0.094 13.0 0.1 2.5 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3683 PF12447.3 EKG18912.1 - 0.11 12.2 0.7 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) DUF883 PF05957.8 EKG18912.1 - 0.35 11.3 2.5 0.65 10.4 0.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) HrpB7 PF09486.5 EKG18912.1 - 0.47 10.3 5.3 0.51 10.2 0.8 2.5 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2205 PF10224.4 EKG18912.1 - 7.4 6.2 7.0 0.82 9.2 0.5 2.5 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) GWT1 PF06423.7 EKG18913.1 - 0.0084 16.2 0.7 0.0092 16.0 0.5 1.2 1 0 0 1 1 1 1 GWT1 DUF2232 PF09991.4 EKG18913.1 - 0.05 12.6 0.8 0.059 12.3 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PRA1 PF03208.14 EKG18913.1 - 0.15 11.3 2.4 0.3 10.4 1.7 1.4 1 1 0 1 1 1 0 PRA1 family protein DUF1072 PF06380.6 EKG18913.1 - 3.7 7.2 5.4 1.1 8.9 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1072) YopD PF05844.7 EKG18914.1 - 0.096 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 YopD protein Apolipoprotein PF01442.13 EKG18916.1 - 1.2e-05 24.9 6.6 1.8e-05 24.3 4.6 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Nbl1_Borealin_N PF10444.4 EKG18916.1 - 0.00035 19.8 4.5 0.16 11.3 0.4 2.4 1 1 1 2 2 2 2 Nbl1 / Borealin N terminal Baculo_PEP_C PF04513.7 EKG18916.1 - 0.00075 19.3 0.3 1.2 9.0 0.0 2.5 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.6 EKG18916.1 - 0.0073 16.0 4.5 0.013 15.2 3.1 1.4 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) RPW8 PF05659.6 EKG18916.1 - 0.0098 15.4 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 IncA PF04156.9 EKG18916.1 - 0.022 14.3 3.9 0.033 13.7 2.7 1.2 1 0 0 1 1 1 0 IncA protein RRF PF01765.14 EKG18916.1 - 0.049 13.0 5.4 0.036 13.5 2.5 1.7 1 1 0 1 1 1 0 Ribosome recycling factor OmpH PF03938.9 EKG18916.1 - 0.054 13.4 1.3 0.09 12.7 0.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 EKG18916.1 - 0.13 10.6 0.8 0.17 10.3 0.6 1.1 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 EKG18916.1 - 0.16 11.7 1.5 0.3 10.8 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.4 EKG18916.1 - 0.26 10.6 2.6 5.5 6.4 0.4 2.6 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin NPV_P10 PF05531.7 EKG18916.1 - 0.4 10.9 3.4 3.1 8.1 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mitofilin PF09731.4 EKG18916.1 - 0.45 9.0 5.8 0.65 8.5 4.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ISG65-75 PF11727.3 EKG18916.1 - 0.46 9.4 2.9 0.72 8.8 2.0 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF883 PF05957.8 EKG18916.1 - 0.55 10.6 6.6 6.1 7.3 3.9 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 EKG18916.1 - 1.3 9.4 8.7 0.43 11.0 3.4 2.1 2 1 1 3 3 2 0 Plasmid replication region DNA-binding N-term Syntaxin-6_N PF09177.6 EKG18916.1 - 1.6 9.2 6.1 5.9 7.3 2.1 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal YtxH PF12732.2 EKG18916.1 - 5.9 7.3 5.2 66 3.9 3.6 2.3 1 1 0 1 1 1 0 YtxH-like protein HalX PF08663.5 EKG18916.1 - 9.6 6.2 9.7 13 5.8 2.7 3.3 1 1 2 3 3 3 0 HalX domain Pkinase PF00069.20 EKG18917.1 - 1.7e-08 33.9 0.0 3.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG18917.1 - 8.8e-07 28.2 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_3 PF01494.14 EKG18918.1 - 1.5e-11 43.9 0.0 1.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG18918.1 - 0.11 11.4 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 EKG18918.1 - 0.16 10.8 0.0 5.6 5.6 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Acetyltransf_7 PF13508.1 EKG18919.1 - 1.3e-12 47.6 0.1 2e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG18919.1 - 9.7e-12 44.7 0.2 1.7e-11 43.9 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG18919.1 - 1.5e-09 38.0 0.1 1.9e-09 37.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG18919.1 - 2.7e-09 37.3 0.1 3.7e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG18919.1 - 1.3e-08 34.4 0.0 2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EKG18919.1 - 4.9e-06 26.5 0.2 9.2e-06 25.6 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG18919.1 - 5e-06 26.3 0.1 7.3e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EKG18919.1 - 1.1e-05 25.3 0.0 1.4e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG18919.1 - 0.00035 20.3 0.0 0.001 18.9 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.1 EKG18919.1 - 0.019 14.9 1.1 0.084 12.8 0.1 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain TGT PF01702.13 EKG18920.1 - 2.8e-37 128.2 0.0 3.6e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase F-box-like PF12937.2 EKG18921.1 - 1.1e-06 28.2 0.1 4.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKG18921.1 - 1.1e-05 24.9 0.1 2.8e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 F-box domain Glyco_hydro_28 PF00295.12 EKG18922.1 - 8.3e-33 113.7 6.8 1.1e-32 113.2 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EKG18922.1 - 1.1e-07 32.2 9.4 4.2e-07 30.3 6.1 2.1 1 1 1 2 2 2 1 Pectate lyase superfamily protein Glyco_transf_15 PF01793.11 EKG18923.1 - 1.2e-135 451.7 11.9 1.5e-135 451.4 8.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EKG18924.1 - 4.8e-78 262.8 2.4 6.2e-78 262.4 1.7 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EKG18924.1 - 0.00011 20.4 0.1 0.00044 18.4 0.0 2.0 3 0 0 3 3 3 1 gamma-Tubulin ring complex non-core subunit mod21 DUF1802 PF08819.6 EKG18924.1 - 0.088 12.4 2.8 4.1 6.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1802) Pol_alpha_B_N PF08418.5 EKG18925.1 - 0.69 9.4 5.9 1.1 8.7 4.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 EKG18925.1 - 0.83 8.9 8.3 0.97 8.7 5.7 1.2 1 0 0 1 1 1 0 Vta1 like UPF0029 PF01205.14 EKG18926.1 - 5.4e-32 109.7 0.0 8.1e-32 109.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EKG18926.1 - 1.1e-08 35.0 0.0 1.7e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RWD domain TrkH PF02386.11 EKG18928.1 - 8.4e-122 406.1 13.1 1.6e-119 398.6 5.7 2.1 2 0 0 2 2 2 2 Cation transport protein DUF4328 PF14219.1 EKG18928.1 - 0.17 11.2 3.8 1.2 8.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Glycogen_syn PF05693.8 EKG18929.1 - 0 1121.4 0.0 0 1121.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EKG18929.1 - 1.1e-06 28.1 0.0 0.0053 16.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EKG18929.1 - 4.2e-05 23.7 0.0 8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EKG18929.1 - 0.0036 16.8 0.0 0.0077 15.7 0.0 1.7 1 0 0 1 1 1 1 Starch synthase catalytic domain MMS19_N PF14500.1 EKG18929.1 - 0.11 11.7 0.1 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF759 PF05537.6 EKG18929.1 - 0.16 10.6 0.4 0.27 9.9 0.3 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) MCM PF00493.18 EKG18930.1 - 9.7e-144 478.2 0.3 1.5e-143 477.5 0.2 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKG18930.1 - 6.1e-19 68.6 1.4 1.1e-18 67.8 0.4 1.9 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EKG18930.1 - 8.4e-07 28.3 0.0 0.00023 20.4 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EKG18930.1 - 1.6e-05 24.6 0.0 4.5e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EKG18930.1 - 0.00047 19.7 0.0 0.0018 17.8 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EKG18930.1 - 0.016 15.4 1.4 0.27 11.4 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EKG18930.1 - 0.022 15.1 1.6 0.059 13.7 0.4 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EKG18930.1 - 0.037 13.4 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF605 PF04652.11 EKG18931.1 - 0.035 13.5 16.2 0.063 12.6 11.2 1.5 1 0 0 1 1 1 0 Vta1 like CTD_bind PF04818.8 EKG18931.1 - 0.054 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. DUF3433 PF11915.3 EKG18932.1 - 1.2e-41 140.7 9.2 2.1e-23 82.2 0.8 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) SusE PF14292.1 EKG18932.1 - 0.0023 17.7 1.6 0.0065 16.2 1.1 1.7 1 0 0 1 1 1 1 SusE outer membrane protein RskA PF10099.4 EKG18932.1 - 0.067 12.9 1.5 4.5 6.9 0.1 3.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Glyco_hydro_61 PF03443.9 EKG18934.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Syntaxin-6_N PF09177.6 EKG18935.1 - 0.0094 16.3 4.2 0.047 14.0 0.3 3.3 2 1 1 3 3 3 1 Syntaxin 6, N-terminal HisKA PF00512.20 EKG18935.1 - 0.77 9.8 4.0 2.7 8.0 0.6 3.1 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain TMF_TATA_bd PF12325.3 EKG18935.1 - 2.1 8.1 7.9 0.27 10.9 0.6 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding RmlD_sub_bind PF04321.12 EKG18936.1 - 1.3e-32 112.8 0.0 4.8e-26 91.2 0.0 2.5 2 1 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.16 EKG18936.1 - 3.2e-13 49.6 0.0 8.4e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG18936.1 - 1.1e-09 37.5 0.3 4.6e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EKG18936.1 - 0.0015 18.5 0.2 0.0038 17.2 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EKG18936.1 - 0.011 15.0 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 EKG18936.1 - 0.017 13.8 0.0 2.4 6.7 0.0 2.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EKG18936.1 - 0.022 14.6 4.2 0.047 13.6 1.0 2.5 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EKG18936.1 - 0.081 11.8 0.4 5.1 5.9 0.2 2.7 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Transglut_core PF01841.14 EKG18937.1 - 2.1e-11 44.0 0.4 4.5e-11 42.9 0.3 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EKG18937.1 - 1.6e-08 33.9 0.1 3.4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG18937.1 - 1.3e-05 24.5 2.7 1.4e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EKG18937.1 - 0.00048 19.6 1.1 0.00077 19.0 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain XRN_N PF03159.13 EKG18938.1 - 4.6e-103 343.7 0.0 7.6e-103 342.9 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus IMS PF00817.15 EKG18938.1 - 0.15 11.8 0.0 0.63 9.8 0.0 2.0 2 0 0 2 2 2 0 impB/mucB/samB family WD40 PF00400.27 EKG18939.1 - 1.5e-36 122.9 3.7 7.8e-09 35.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EKG18939.1 - 1.4e-24 85.7 0.3 3.2e-24 84.5 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex zf-CHCC PF10276.4 EKG18940.1 - 1.6e-14 53.4 1.3 2.5e-14 52.7 0.9 1.3 1 0 0 1 1 1 1 Zinc-finger domain DUF1237 PF06824.6 EKG18942.1 - 2.1e-161 537.3 0.0 2.4e-161 537.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Dynamin_M PF01031.15 EKG18944.1 - 5.4e-69 232.2 0.1 6.4e-69 231.9 0.1 1.0 1 0 0 1 1 1 1 Dynamin central region AMP-binding PF00501.23 EKG18945.1 - 9.7e-15 53.8 0.0 4.7e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Met_synt_B12 PF02965.12 EKG18945.1 - 0.048 12.8 0.1 1.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Vitamin B12 dependent methionine synthase, activation domain ACT_7 PF13840.1 EKG18946.1 - 2e-20 72.0 0.0 3.2e-06 26.5 0.0 3.5 3 0 0 3 3 3 3 ACT domain HET PF06985.6 EKG18947.1 - 0.047 13.8 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) GMC_oxred_N PF00732.14 EKG18948.1 - 1.5e-28 99.7 1.3 7.1e-28 97.6 0.2 2.5 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG18948.1 - 2.8e-25 89.2 0.4 6.1e-25 88.1 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.13 EKG18948.1 - 3e-08 33.1 5.2 1e-07 31.4 3.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain DAO PF01266.19 EKG18948.1 - 3.3e-08 32.8 0.4 0.0037 16.2 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG18948.1 - 8.2e-08 31.5 0.9 0.0059 15.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EKG18948.1 - 6.3e-06 26.3 0.0 0.01 15.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG18948.1 - 0.00018 21.4 0.0 0.00084 19.3 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG18948.1 - 0.0019 18.5 0.1 0.17 12.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG18948.1 - 0.0022 16.5 0.1 0.017 13.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein DOMON PF03351.12 EKG18948.1 - 0.0064 16.4 0.1 0.02 14.8 0.0 1.8 1 0 0 1 1 1 1 DOMON domain FAD_oxidored PF12831.2 EKG18948.1 - 0.0076 15.3 0.0 2.3 7.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EKG18948.1 - 0.018 14.1 0.1 0.032 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EKG18948.1 - 0.02 14.7 0.6 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG18948.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Glyco_hydro_61 PF03443.9 EKG18949.1 - 5e-65 219.3 0.0 6e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SprB PF13573.1 EKG18949.1 - 9.9 5.8 8.1 20 4.9 0.6 2.6 2 0 0 2 2 2 0 SprB repeat WD40 PF00400.27 EKG18950.1 - 3.4e-55 182.0 25.4 1.3e-12 47.0 0.1 12.1 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 EKG18950.1 - 3.3e-28 97.7 0.0 4.8e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EKG18950.1 - 3.2e-06 26.9 0.1 0.028 14.1 0.0 5.1 5 1 0 6 6 6 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EKG18950.1 - 0.00022 19.5 5.5 0.33 9.0 0.5 4.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 IKI3 PF04762.7 EKG18950.1 - 0.001 16.9 0.0 0.2 9.4 0.0 2.3 2 0 0 2 2 2 2 IKI3 family Nbas_N PF15492.1 EKG18950.1 - 0.0094 15.0 0.1 6.1 5.8 0.0 3.2 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 EKG18951.1 - 1.7e-115 384.9 0.2 2.7e-115 384.2 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EKG18951.1 - 1.5e-07 31.3 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG18951.1 - 4.6e-06 26.1 0.2 7.8e-05 22.1 0.2 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EKG18951.1 - 9e-06 24.9 0.0 2.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKG18951.1 - 0.0015 18.6 0.1 0.0051 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EKG18951.1 - 0.0021 18.5 0.1 0.0084 16.5 0.1 2.0 1 1 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EKG18951.1 - 0.0027 17.2 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EKG18951.1 - 0.0047 16.0 0.0 0.0094 15.0 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EKG18951.1 - 0.0084 14.9 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EKG18951.1 - 0.0085 15.5 0.0 0.02 14.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 EKG18951.1 - 0.014 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EKG18951.1 - 0.03 13.7 0.5 0.087 12.2 0.4 1.8 1 1 0 1 1 1 0 Ras family T2SE PF00437.15 EKG18951.1 - 0.037 12.9 0.3 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.1 EKG18951.1 - 0.04 13.9 1.1 0.34 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EKG18951.1 - 0.041 13.5 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 EKG18951.1 - 0.049 12.6 1.2 0.11 11.4 0.9 1.7 1 1 0 1 1 1 0 KAP family P-loop domain ABC_tran PF00005.22 EKG18951.1 - 0.05 13.9 0.3 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 EKG18951.1 - 0.05 13.0 0.3 2.4 7.6 0.2 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EKG18951.1 - 0.058 13.2 7.3 0.56 10.0 0.1 3.1 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EKG18951.1 - 0.064 12.9 0.1 0.064 12.9 0.1 1.9 2 0 0 2 2 2 0 Archaeal ATPase Atg14 PF10186.4 EKG18951.1 - 0.068 12.1 4.5 0.15 10.9 3.1 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sigma54_activat PF00158.21 EKG18951.1 - 0.07 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.12 EKG18951.1 - 0.1 12.1 0.8 9.4 5.6 0.1 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EKG18951.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Myc-LZ PF02344.10 EKG18951.1 - 0.21 11.2 5.8 0.2 11.2 0.4 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain ArgK PF03308.11 EKG18951.1 - 0.29 9.8 1.4 0.9 8.2 0.0 2.4 3 0 0 3 3 3 0 ArgK protein Ribosomal_L6e PF01159.14 EKG18951.1 - 1.7 8.8 6.3 3.8 7.8 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L6e Cep57_CLD_2 PF14197.1 EKG18951.1 - 5.2 7.0 9.8 23 5.0 6.6 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 WD40 PF00400.27 EKG18952.1 - 2.8e-41 137.9 7.5 6.2e-10 38.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EKG18952.1 - 7.8e-05 22.2 0.3 0.026 14.0 0.1 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EKG18952.1 - 0.006 16.8 6.7 0.5 10.7 0.0 4.7 5 1 0 5 5 5 1 PQQ-like domain PQQ PF01011.16 EKG18952.1 - 0.026 14.0 0.1 34 4.2 0.0 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat Coatomer_WDAD PF04053.9 EKG18952.1 - 0.16 10.7 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Radial_spoke PF04712.7 EKG18953.1 - 0.022 13.5 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein DUF4366 PF14283.1 EKG18953.1 - 0.045 13.1 0.4 0.045 13.1 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Apc15p PF05841.6 EKG18954.1 - 0.11 13.2 0.3 0.16 12.7 0.2 1.2 1 0 0 1 1 1 0 Apc15p protein COG2 PF06148.6 EKG18955.1 - 0.0004 20.2 0.1 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Sigma70_ner PF04546.8 EKG18955.1 - 0.00049 19.7 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Spt5_N PF11942.3 EKG18955.1 - 0.00089 19.8 3.2 0.00089 19.8 2.2 1.9 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal AF1Q PF15017.1 EKG18955.1 - 0.013 15.3 2.7 0.02 14.8 1.9 1.2 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator DUF3375 PF11855.3 EKG18955.1 - 0.036 12.8 0.7 0.061 12.0 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3375) Nucleoplasmin PF03066.10 EKG18955.1 - 0.06 12.8 2.6 0.083 12.4 1.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EKG18955.1 - 0.31 11.3 9.1 0.56 10.4 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.7 EKG18955.1 - 0.47 8.3 8.3 0.63 7.9 5.8 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EKG18955.1 - 0.54 9.4 2.9 0.69 9.1 2.0 1.1 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.14 EKG18955.1 - 2.3 8.6 8.1 2.1 8.8 4.4 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3749 PF12568.3 EKG18955.1 - 6.1 6.4 6.3 23 4.5 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribosomal_L1 PF00687.16 EKG18956.1 - 2.1e-27 95.9 0.0 2.8e-27 95.4 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family FAD_binding_3 PF01494.14 EKG18959.1 - 1e-25 90.5 0.1 1.3e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EKG18959.1 - 0.00026 20.6 0.0 0.0039 16.8 0.0 2.4 1 1 1 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain PGM_PMM_II PF02879.11 EKG18959.1 - 0.096 13.0 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II FAD_binding_3 PF01494.14 EKG18960.1 - 9e-13 47.9 0.1 9.9e-13 47.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG18960.1 - 0.00051 19.0 0.1 0.00061 18.7 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG18960.1 - 0.00086 19.2 0.0 0.0017 18.3 0.0 1.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG18960.1 - 0.0016 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 EKG18960.1 - 0.005 16.5 0.0 0.0056 16.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EKG18960.1 - 0.029 14.1 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 EKG18960.1 - 0.041 13.9 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG18960.1 - 0.046 12.6 0.1 0.066 12.1 0.0 1.3 1 1 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EKG18960.1 - 0.058 12.8 0.2 0.065 12.6 0.1 1.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 EKG18960.1 - 0.065 11.6 0.1 0.19 10.1 0.0 1.6 1 1 1 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EKG18960.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HCO3_cotransp PF00955.16 EKG18961.1 - 9.6e-50 169.6 13.7 5e-29 101.3 3.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF3953 PF13129.1 EKG18961.1 - 0.16 11.6 4.4 3.9 7.1 0.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) SET PF00856.23 EKG18962.1 - 3.9e-10 40.2 0.0 1e-09 38.8 0.0 1.9 1 1 0 1 1 1 1 SET domain Sugar_tr PF00083.19 EKG18963.1 - 4.9e-124 414.3 22.2 5.6e-124 414.1 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG18963.1 - 7.8e-29 100.4 16.1 7.8e-29 100.4 11.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD-oxidase_C PF02913.14 EKG18964.1 - 4.1e-58 196.6 0.0 5.8e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EKG18964.1 - 1.6e-37 128.0 0.3 2.8e-37 127.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Proteasome PF00227.21 EKG18965.1 - 1.9e-55 187.0 0.1 2.6e-55 186.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKG18965.1 - 2.5e-13 49.0 0.1 2.5e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3071 PF11268.3 EKG18965.1 - 0.081 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) zf-CHY PF05495.7 EKG18966.1 - 6.8e-14 51.7 21.5 8.8e-14 51.4 14.9 1.1 1 0 0 1 1 1 1 CHY zinc finger C1_4 PF07975.7 EKG18966.1 - 0.44 10.5 15.5 1.5 8.8 5.1 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 EKG18966.1 - 0.79 9.5 13.1 15 5.5 0.0 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Cys_rich_KTR PF14205.1 EKG18966.1 - 1.1 8.7 8.8 2.7 7.5 0.1 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR HypA PF01155.14 EKG18966.1 - 1.2 8.8 12.7 0.05 13.3 3.3 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Evr1_Alr PF04777.8 EKG18966.1 - 3.5 7.6 13.9 2.2e+02 1.8 9.6 2.9 1 1 0 1 1 1 0 Erv1 / Alr family zf-TFIIB PF13453.1 EKG18966.1 - 4.5 6.5 8.5 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-RING_3 PF14369.1 EKG18966.1 - 6.2 6.9 13.7 1.2 9.1 5.4 2.6 1 1 2 3 3 3 0 zinc-finger Exo_endo_phos PF03372.18 EKG18967.1 - 1.6e-22 80.6 0.5 2.6e-22 79.9 0.1 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EKG18967.1 - 0.11 12.2 0.3 0.8 9.4 0.0 2.5 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EKG18967.1 - 0.37 10.7 2.8 1.2 9.1 0.5 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat GFA PF04828.9 EKG18968.1 - 5.8e-11 42.1 2.1 5.8e-11 42.1 1.4 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-LSD1 PF06943.7 EKG18968.1 - 0.052 13.1 5.8 0.78 9.3 0.3 2.5 2 0 0 2 2 2 0 LSD1 zinc finger PyrI_C PF02748.10 EKG18968.1 - 0.11 11.9 0.3 0.11 11.9 0.2 1.9 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain HDA2-3 PF11496.3 EKG18969.1 - 4.7e-18 65.0 0.0 1.6e-16 60.0 0.0 2.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 p450 PF00067.17 EKG18971.1 - 1.7e-79 267.5 0.0 2.2e-79 267.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.9 EKG18972.1 - 4e-29 102.0 1.2 5.2e-29 101.6 0.8 1.1 1 0 0 1 1 1 1 Amidohydrolase p450 PF00067.17 EKG18973.1 - 6.7e-74 249.0 0.0 8.8e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 EKG18975.1 - 1.1e-14 54.4 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG18975.1 - 5.2e-13 48.3 0.0 9.3e-13 47.4 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG18975.1 - 3.8e-11 43.3 0.1 2e-10 41.0 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG18975.1 - 4.8e-09 35.8 0.1 7.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EKG18975.1 - 9e-08 31.3 0.0 1.5e-07 30.5 0.0 1.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EKG18975.1 - 4.6e-07 29.0 0.1 0.00031 19.7 0.0 2.0 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EKG18975.1 - 2.7e-05 24.1 1.9 3.2e-05 23.9 0.1 2.0 2 1 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EKG18975.1 - 0.015 14.2 0.0 0.025 13.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.5 EKG18975.1 - 0.015 14.9 0.4 0.33 10.5 0.3 2.3 1 1 0 1 1 1 0 KR domain COesterase PF00135.23 EKG18976.1 - 3.8e-38 131.5 0.0 3e-37 128.5 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG18976.1 - 4.7e-06 26.3 0.1 1.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG18976.1 - 0.13 11.4 0.2 0.25 10.5 0.2 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family adh_short PF00106.20 EKG18977.1 - 1.6e-28 99.7 2.2 2.2e-28 99.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG18977.1 - 1.2e-14 54.3 0.1 1.7e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG18977.1 - 4.2e-12 46.3 0.2 6e-12 45.8 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG18977.1 - 1.4e-08 34.5 0.3 2.8e-08 33.4 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG18977.1 - 7.5e-08 31.6 0.0 9.3e-08 31.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EKG18977.1 - 0.0036 17.3 0.4 0.0083 16.2 0.3 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EKG18977.1 - 0.0075 16.6 0.2 0.018 15.4 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EKG18977.1 - 0.018 14.7 0.5 0.03 13.9 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EKG18977.1 - 0.03 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.11 EKG18977.1 - 0.037 13.4 0.1 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 EKG18978.1 - 3.1e-33 114.9 55.5 2.2e-32 112.1 38.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SnoaL_2 PF12680.2 EKG18979.1 - 0.023 15.0 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain adh_short PF00106.20 EKG18980.1 - 2.9e-25 89.1 7.2 3.9e-25 88.6 5.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG18980.1 - 2.7e-11 43.4 3.6 3.6e-11 43.0 2.5 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG18980.1 - 6.3e-09 35.9 0.1 8.5e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EKG18980.1 - 0.19 11.5 4.7 1.2 8.9 3.3 2.3 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_4 PF01565.18 EKG18981.1 - 1.6e-18 66.5 0.6 1.6e-18 66.5 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Epimerase PF01370.16 EKG18982.1 - 1.2e-21 77.2 0.0 1.7e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG18982.1 - 3.6e-12 45.7 0.1 7.5e-11 41.4 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EKG18982.1 - 7.8e-11 41.1 0.0 8.7e-11 41.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG18982.1 - 1.3e-09 38.3 0.2 2.8e-09 37.2 0.1 1.7 1 1 1 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EKG18982.1 - 3.8e-07 30.1 0.0 7.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG18982.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EKG18982.1 - 0.00062 18.7 0.0 0.0013 17.7 0.0 1.4 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EKG18982.1 - 0.005 15.7 0.0 0.0091 14.9 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EKG18982.1 - 0.01 15.1 0.1 0.023 13.9 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Acyl_transf_1 PF00698.16 EKG18983.1 - 4.7e-90 302.1 1.2 4.7e-90 302.1 0.8 2.0 2 1 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.21 EKG18983.1 - 1.2e-81 273.9 0.2 9.9e-81 270.9 0.1 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EKG18983.1 - 1.9e-61 206.8 0.2 4.9e-61 205.5 0.1 1.8 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EKG18983.1 - 8e-53 178.7 0.2 2.7e-52 177.0 0.2 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EKG18983.1 - 3.2e-41 139.9 2.9 1.8e-40 137.4 1.5 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EKG18983.1 - 5.6e-16 58.5 0.2 1.1e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EKG18983.1 - 7.9e-10 38.8 0.0 2.2e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EKG18983.1 - 4.9e-05 22.4 0.1 0.00018 20.6 0.1 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain Cupin_2 PF07883.6 EKG18984.1 - 0.00044 19.6 0.4 0.0016 17.9 0.1 2.0 2 0 0 2 2 2 1 Cupin domain ABC2_membrane PF01061.19 EKG18985.1 - 3e-80 268.3 50.8 5.9e-42 143.2 11.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EKG18985.1 - 2.9e-34 118.3 0.0 4.6e-16 59.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG18985.1 - 2.9e-29 100.7 0.2 6e-24 83.6 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EKG18985.1 - 1.9e-10 40.6 0.1 8.1e-10 38.6 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EKG18985.1 - 1.1e-05 24.6 33.6 5.9e-05 22.2 10.1 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EKG18985.1 - 1.3e-05 24.7 0.2 0.0071 15.7 0.1 3.1 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EKG18985.1 - 2.6e-05 25.0 0.0 0.019 15.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EKG18985.1 - 5.9e-05 23.1 0.1 0.097 12.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKG18985.1 - 7.4e-05 22.1 0.2 0.0063 16.0 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EKG18985.1 - 7.7e-05 22.5 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKG18985.1 - 0.00013 22.0 0.1 0.014 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG18985.1 - 0.00025 21.1 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG18985.1 - 0.00065 19.4 0.4 0.89 9.3 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 EKG18985.1 - 0.00096 18.6 1.1 0.038 13.4 0.2 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EKG18985.1 - 0.0019 17.7 0.5 0.85 9.2 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EKG18985.1 - 0.002 17.3 0.0 0.0059 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EKG18985.1 - 0.0028 17.6 0.1 0.037 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG18985.1 - 0.0057 16.9 0.4 1.4 9.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 EKG18985.1 - 0.012 15.1 0.3 2.6 7.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EKG18985.1 - 0.019 14.6 0.4 5.7 6.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain FtsK_SpoIIIE PF01580.13 EKG18985.1 - 0.026 14.0 0.9 1 8.8 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EKG18985.1 - 0.037 13.7 0.6 4.2 7.0 0.0 3.1 4 0 0 4 4 4 0 Archaeal ATPase AAA PF00004.24 EKG18985.1 - 0.05 13.8 0.0 16 5.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EKG18985.1 - 0.43 9.5 0.0 2.2 7.2 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain Opi1 PF08618.5 EKG18986.1 - 2.1e-58 198.2 14.3 2.7e-41 141.8 3.0 3.3 1 1 2 3 3 3 3 Transcription factor Opi1 tRNA-synt_2b PF00587.20 EKG18987.1 - 4.6e-31 107.7 0.0 7.8e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EKG18987.1 - 2.3e-18 66.2 11.0 2.3e-18 66.2 7.6 1.8 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Toxin_39 PF15500.1 EKG18987.1 - 0.69 10.0 5.3 0.2 11.8 1.0 2.1 2 0 0 2 2 2 0 Putative RNase-like toxin Cytochrom_C552 PF02335.10 EKG18987.1 - 2.3 6.8 10.8 0.71 8.4 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c552 Peptidase_M18 PF02127.10 EKG18988.1 - 2.6e-129 431.4 0.0 3e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) HRDC PF00570.18 EKG18990.1 - 1.7e-39 133.3 2.3 2.1e-14 52.9 0.0 3.6 3 0 0 3 3 3 3 HRDC domain DNA_pol_A_exo1 PF01612.15 EKG18990.1 - 1.9e-12 47.0 0.0 2.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HHH PF00633.18 EKG18990.1 - 0.0048 16.5 0.1 3.1 7.6 0.0 2.9 2 0 0 2 2 2 2 Helix-hairpin-helix motif BRCT PF00533.21 EKG18990.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Helicase_Sgs1 PF11408.3 EKG18990.1 - 0.067 13.0 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Sgs1 RecQ helicase Lipase_GDSL PF00657.17 EKG18992.1 - 1.2e-13 51.4 0.0 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKG18992.1 - 1.4e-13 51.3 0.3 2e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pectate_lyase_3 PF12708.2 EKG18993.1 - 2.8e-51 174.8 33.9 1.4e-40 139.7 9.7 3.9 4 1 0 5 5 5 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EKG18993.1 - 0.011 15.2 0.8 0.031 13.7 0.0 2.2 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Cupin_2 PF07883.6 EKG18994.1 - 8.6e-10 37.9 0.0 1.3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EKG18994.1 - 0.0012 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Cupin DUF1498 PF07385.7 EKG18994.1 - 0.0016 17.6 0.0 0.2 10.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1498) MannoseP_isomer PF01050.13 EKG18994.1 - 0.063 12.8 0.0 0.092 12.3 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase GST_C PF00043.20 EKG18995.1 - 1.8e-09 37.4 0.0 2.9e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG18995.1 - 3.2e-06 26.9 0.1 6.9e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG18995.1 - 3.6e-06 27.3 0.0 5.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EKG18995.1 - 0.057 13.5 0.1 0.83 9.8 0.0 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4379 PF14311.1 EKG18995.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Fungal_trans PF04082.13 EKG18997.1 - 1.4e-15 56.8 0.2 2.1e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG18997.1 - 5e-08 32.7 11.3 1.1e-07 31.6 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyoma_agno PF01736.11 EKG18997.1 - 0.11 12.1 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Polyomavirus agnoprotein Oxidored_molyb PF00174.14 EKG18998.1 - 1.4e-33 115.6 0.1 2.1e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain SIT PF15330.1 EKG18999.1 - 0.31 11.1 3.7 1.9 8.6 1.1 3.1 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Ribonuclease PF00545.15 EKG19002.1 - 0.00074 19.5 0.3 0.0013 18.7 0.2 1.4 1 0 0 1 1 1 1 ribonuclease tRNA-synt_1e PF01406.14 EKG19003.1 - 1.2e-114 382.5 0.0 1.8e-114 381.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EKG19003.1 - 7.1e-05 21.6 0.1 0.16 10.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1c PF00749.16 EKG19003.1 - 0.045 12.4 0.8 0.11 11.1 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain GCD14 PF08704.5 EKG19004.1 - 1.6e-63 214.4 4.1 1.5e-20 73.7 0.0 4.2 2 1 1 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EKG19004.1 - 0.0025 17.8 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG19004.1 - 0.0089 16.5 0.3 0.29 11.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EKG19004.1 - 0.065 12.2 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DIOX_N PF14226.1 EKG19005.1 - 2.5e-23 82.7 0.0 3.9e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG19005.1 - 2.2e-20 72.8 0.0 4.2e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBM_19 PF03427.8 EKG19005.1 - 0.67 9.7 0.1 0.67 9.7 0.0 2.5 2 1 1 3 3 3 0 Carbohydrate binding domain (family 19) PHO4 PF01384.15 EKG19006.1 - 1.3e-115 385.5 12.0 1.5e-115 385.3 8.3 1.0 1 0 0 1 1 1 1 Phosphate transporter family UNC-50 PF05216.8 EKG19006.1 - 0.031 13.4 0.5 0.085 12.0 0.1 1.9 2 0 0 2 2 2 0 UNC-50 family HCR PF07111.7 EKG19007.1 - 0.00046 18.3 9.6 0.00064 17.8 6.6 1.1 1 0 0 1 1 1 1 Alpha helical coiled-coil rod protein (HCR) MIS13 PF08202.6 EKG19007.1 - 0.00064 18.8 2.7 0.00077 18.6 1.9 1.1 1 0 0 1 1 1 1 Mis12-Mtw1 protein family FliJ PF02050.11 EKG19007.1 - 0.0017 18.4 6.7 0.21 11.6 0.7 2.2 2 0 0 2 2 2 2 Flagellar FliJ protein NBP1 PF08537.5 EKG19007.1 - 0.0087 15.3 6.4 0.011 15.0 4.4 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 CENP-F_leu_zip PF10473.4 EKG19007.1 - 0.015 15.1 8.2 0.37 10.6 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EKG19007.1 - 0.016 13.9 10.9 0.1 11.2 1.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.6 EKG19007.1 - 0.016 15.0 8.8 0.25 11.1 1.1 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Flagellin_C PF00700.16 EKG19007.1 - 0.016 15.3 0.8 4.9 7.3 0.0 2.4 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region LXG PF04740.7 EKG19007.1 - 0.021 14.6 0.3 0.049 13.4 0.2 1.6 1 1 0 1 1 1 0 LXG domain of WXG superfamily Laminin_II PF06009.7 EKG19007.1 - 0.043 13.5 3.9 1 9.1 0.2 2.1 2 0 0 2 2 2 0 Laminin Domain II GP41 PF00517.12 EKG19007.1 - 0.072 12.6 0.9 1 8.8 0.2 2.1 2 0 0 2 2 2 0 Retroviral envelope protein IncA PF04156.9 EKG19007.1 - 0.073 12.6 11.1 1.8 8.1 3.9 2.1 2 0 0 2 2 2 0 IncA protein V-SNARE_C PF12352.3 EKG19007.1 - 0.13 12.3 2.3 0.35 10.9 1.6 1.7 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CHDCT2 PF08074.6 EKG19007.1 - 0.17 11.5 2.4 7.8 6.1 0.1 2.2 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain AAA_13 PF13166.1 EKG19007.1 - 0.24 9.8 7.0 0.51 8.7 4.9 1.4 1 1 0 1 1 1 0 AAA domain HrpB7 PF09486.5 EKG19007.1 - 0.29 11.0 9.7 1.8 8.5 1.2 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.1 EKG19007.1 - 0.38 10.1 10.1 0.15 11.4 0.6 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FANCI_S3 PF14677.1 EKG19007.1 - 0.48 9.7 4.7 2 7.7 0.4 2.0 2 0 0 2 2 2 0 FANCI solenoid 3 Uds1 PF15456.1 EKG19007.1 - 0.6 10.1 9.0 4.8 7.1 6.2 2.1 1 1 0 1 1 1 0 Up-regulated During Septation Med7 PF05983.6 EKG19007.1 - 0.74 9.5 3.1 0.47 10.2 0.1 1.9 2 0 0 2 2 2 0 MED7 protein DUF1664 PF07889.7 EKG19007.1 - 0.76 9.5 4.6 3.8 7.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 EKG19007.1 - 1.1 9.6 8.2 0.32 11.3 2.3 2.5 1 1 2 3 3 3 0 Snapin/Pallidin COG2 PF06148.6 EKG19007.1 - 1.2 9.0 5.9 1.1 9.1 0.6 2.6 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tho2 PF11262.3 EKG19007.1 - 1.7 7.6 5.3 0.31 10.0 0.2 1.8 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Siah-Interact_N PF09032.6 EKG19007.1 - 1.9 8.6 7.4 11 6.1 1.5 2.9 2 1 0 2 2 2 0 Siah interacting protein, N terminal DUF4140 PF13600.1 EKG19007.1 - 3.3 8.2 14.8 12 6.4 0.9 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) KxDL PF10241.4 EKG19007.1 - 4.2 7.3 7.7 1 9.2 1.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein Atg14 PF10186.4 EKG19007.1 - 4.5 6.1 13.8 2.3 7.0 4.5 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 zf-RanBP PF00641.13 EKG19008.1 - 1.1e-19 69.1 9.9 6.8e-11 41.0 1.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EKG19008.1 - 2.8e-08 33.2 0.0 1.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EKG19008.1 - 1.7e-07 31.6 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EKG19008.1 - 6.3e-07 29.2 0.0 8.1e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EKG19008.1 - 0.98 9.2 8.0 0.87 9.4 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EKG19008.1 - 1.2 8.4 5.9 9.7 5.5 1.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain F-box-like PF12937.2 EKG19009.1 - 1.5e-07 31.0 0.0 3.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Vps54 PF07928.7 EKG19010.1 - 7.8e-44 149.0 2.1 1.2e-42 145.2 0.2 2.6 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EKG19010.1 - 3.6e-06 26.0 0.2 3.6e-06 26.0 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) Tup_N PF08581.5 EKG19012.1 - 0.016 15.3 0.4 0.029 14.5 0.3 1.3 1 0 0 1 1 1 0 Tup N-terminal ParA PF10609.4 EKG19013.1 - 5.1e-35 119.2 0.1 8.7e-35 118.4 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EKG19013.1 - 2.8e-16 59.5 0.0 4.6e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EKG19013.1 - 9.1e-07 28.2 0.0 7e-06 25.3 0.0 2.0 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EKG19013.1 - 1e-06 28.7 0.0 3.1e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EKG19013.1 - 2.5e-06 26.7 0.9 3.6e-05 22.9 0.5 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 EKG19013.1 - 0.0011 17.8 0.2 0.0017 17.1 0.1 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EKG19013.1 - 0.0067 15.8 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EKG19013.1 - 0.012 14.9 0.1 0.026 13.9 0.1 1.5 1 0 0 1 1 1 0 YhjQ protein AAA_26 PF13500.1 EKG19013.1 - 0.019 14.5 0.9 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EKG19013.1 - 0.022 13.9 0.5 0.044 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 EKG19013.1 - 0.032 13.8 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase VWA_3 PF13768.1 EKG19014.1 - 2.1e-06 27.5 0.0 4.8e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EKG19014.1 - 4.4e-06 26.9 0.0 5.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EKG19014.1 - 0.00013 21.7 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain PH PF00169.24 EKG19015.1 - 0.0061 16.7 0.3 0.013 15.6 0.2 1.5 1 0 0 1 1 1 1 PH domain Spore_coat_CotO PF14153.1 EKG19015.1 - 1.6 8.1 14.6 3.5 7.0 10.1 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Borrelia_P83 PF05262.6 EKG19015.1 - 5.8 5.0 13.8 9.1 4.4 9.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Glyco_transf_25 PF01755.12 EKG19016.1 - 0.13 11.9 0.0 0.66 9.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Transp_cyt_pur PF02133.10 EKG19017.1 - 2e-61 207.9 21.4 2.3e-61 207.6 14.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NPCC PF08058.6 EKG19018.1 - 1.7e-14 53.8 0.0 2.3e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component CoaE PF01121.15 EKG19019.1 - 4.4e-21 75.0 0.0 5.8e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase FERM_M PF00373.13 EKG19019.1 - 0.037 14.1 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 FERM central domain DUF2370 PF10176.4 EKG19019.1 - 0.053 12.8 0.1 0.06 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DAO PF01266.19 EKG19021.1 - 5.8e-85 285.3 0.8 1.1e-41 142.9 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG19021.1 - 3.3e-11 43.4 0.0 0.013 15.4 0.0 4.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG19021.1 - 6.2e-10 38.9 0.0 0.0011 18.9 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG19021.1 - 7.7e-08 32.2 0.3 0.27 10.9 0.0 4.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG19021.1 - 1.8e-06 28.1 0.0 0.48 10.4 0.0 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG19021.1 - 5.6e-06 25.4 0.9 0.076 11.8 0.0 3.7 4 0 0 4 4 4 2 FAD binding domain GIDA PF01134.17 EKG19021.1 - 0.00013 20.9 0.8 0.015 14.2 0.0 3.3 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EKG19021.1 - 0.00018 20.6 0.0 0.13 11.3 0.0 2.8 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 EKG19021.1 - 0.00048 20.4 0.0 0.66 10.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EKG19021.1 - 0.0012 18.8 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EKG19021.1 - 0.0033 17.1 0.0 0.095 12.4 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EKG19021.1 - 0.015 14.7 0.0 0.93 8.8 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EKG19021.1 - 0.018 14.5 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EKG19021.1 - 0.042 12.7 0.0 1.2 7.9 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EKG19021.1 - 0.095 12.3 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EKG19021.1 - 0.1 11.6 0.0 13 4.7 0.0 2.4 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EKG19021.1 - 0.11 11.0 0.0 14 4.0 0.0 3.4 4 0 0 4 4 4 0 HI0933-like protein ThiF PF00899.16 EKG19021.1 - 0.11 12.2 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.15 EKG19021.1 - 0.15 12.1 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EKG19022.1 - 1.4e-06 27.2 0.5 1.8e-06 26.9 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EKG19023.1 - 0.00022 20.0 0.1 0.00025 19.8 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EKG19024.1 - 1.2e-36 126.1 25.1 1.5e-35 122.5 7.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily CENP-I PF07778.6 EKG19024.1 - 0.15 10.2 0.1 0.22 9.6 0.1 1.1 1 0 0 1 1 1 0 Mis6 UPF0093 PF03653.8 EKG19024.1 - 0.77 9.7 4.7 0.22 11.4 0.3 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) FMO-like PF00743.14 EKG19025.1 - 6e-37 127.0 0.0 4.2e-22 78.0 0.0 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EKG19025.1 - 3.8e-22 79.3 0.9 8.7e-20 71.6 0.3 3.4 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG19025.1 - 3.1e-12 46.7 0.0 5.7e-05 23.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG19025.1 - 8.2e-12 44.6 0.0 8.2e-08 31.5 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG19025.1 - 5.9e-10 39.1 0.3 4.4e-07 29.7 0.3 3.5 3 1 0 3 3 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EKG19025.1 - 2.1e-09 37.2 0.0 6.1e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EKG19025.1 - 4.8e-09 35.5 0.5 5.3e-07 28.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EKG19025.1 - 2.5e-06 26.8 0.0 0.00087 18.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EKG19025.1 - 1.3e-05 25.4 1.9 7.9e-05 22.9 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG19025.1 - 4.5e-05 22.6 0.6 0.00011 21.3 0.3 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EKG19025.1 - 6.9e-05 21.4 1.5 0.001 17.6 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EKG19025.1 - 0.00013 21.1 1.6 0.00026 20.1 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.15 EKG19025.1 - 0.00029 20.9 0.0 0.88 9.6 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EKG19025.1 - 0.0004 19.5 0.7 0.00075 18.6 0.3 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG19025.1 - 0.00042 19.2 0.1 0.00092 18.1 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EKG19025.1 - 0.0028 16.6 0.1 0.0079 15.1 0.0 1.7 1 1 1 2 2 2 1 Lycopene cyclase protein ApbA PF02558.11 EKG19025.1 - 0.013 14.9 0.9 0.025 14.0 0.2 1.8 2 0 0 2 2 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EKG19025.1 - 0.014 15.0 0.3 0.05 13.2 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EKG19025.1 - 0.023 14.0 0.0 0.053 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EKG19025.1 - 0.033 14.0 0.1 0.13 12.1 0.0 2.1 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 EKG19025.1 - 0.046 12.5 1.2 0.096 11.5 0.9 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EKG19025.1 - 0.07 11.7 0.4 0.1 11.2 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase 2-Hacid_dh_C PF02826.14 EKG19025.1 - 0.12 11.5 0.0 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SieB PF14163.1 EKG19025.1 - 0.19 11.2 0.0 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B TauD PF02668.11 EKG19026.1 - 3.5e-07 30.1 0.0 4.6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3129 PF11327.3 EKG19026.1 - 0.061 13.1 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3129) PRT_C PF08372.5 EKG19028.1 - 9.4e-06 25.2 2.1 0.00066 19.2 0.1 2.5 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal Tmemb_185A PF10269.4 EKG19028.1 - 0.011 15.3 0.4 0.034 13.7 0.0 1.8 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein Reticulon PF02453.12 EKG19028.1 - 0.23 11.0 0.1 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Reticulon DUF3292 PF11696.3 EKG19028.1 - 1.7 6.3 5.1 10 3.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3292) WD40 PF00400.27 EKG19029.1 - 4.4e-36 121.4 6.4 9.7e-10 37.9 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EKG19029.1 - 3.3e-05 23.6 0.5 0.33 10.6 0.2 3.3 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EKG19029.1 - 6.2e-05 22.5 0.0 0.0027 17.1 0.0 3.2 3 1 1 4 4 4 1 Lipoprotein LpqB beta-propeller domain CLTH PF10607.4 EKG19029.1 - 0.042 13.5 0.1 0.078 12.6 0.1 1.4 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Pmp3 PF01679.12 EKG19030.1 - 4.5e-21 74.2 9.8 5.7e-21 73.9 6.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPPK_C PF12555.3 EKG19030.1 - 0.22 11.2 4.1 0.35 10.6 2.8 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal NapE PF06796.6 EKG19030.1 - 1.2 8.5 3.2 1.7 7.9 2.2 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Asparaginase PF00710.15 EKG19031.1 - 1.6e-100 336.0 0.0 1.8e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Asparaginase NmrA PF05368.8 EKG19032.1 - 2.3e-65 220.1 0.0 3e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG19032.1 - 7.9e-06 25.9 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Ribosomal_L19 PF01245.15 EKG19033.1 - 3e-19 68.8 0.4 5e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 NAP PF00956.13 EKG19034.1 - 2.9e-47 160.8 9.1 4.6e-47 160.2 6.3 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Glyco_hydro_1 PF00232.13 EKG19035.1 - 6.4e-107 357.5 0.4 7.4e-107 357.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 BCDHK_Adom3 PF10436.4 EKG19037.1 - 3.3e-41 140.5 0.1 6.6e-41 139.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EKG19037.1 - 1.3e-10 40.9 0.0 7.2e-10 38.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EKG19037.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EKG19037.1 - 0.13 12.0 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.3 EKG19038.1 - 2.2e-81 272.7 0.0 3e-80 269.0 0.0 2.6 2 1 1 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EKG19038.1 - 5.1e-65 218.8 0.0 1.9e-64 216.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EKG19038.1 - 6e-54 182.9 4.1 1.9e-53 181.3 1.6 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG19038.1 - 3.6e-27 95.5 0.0 6.5e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EKG19038.1 - 4.4e-08 33.3 0.0 1.9e-07 31.3 0.0 2.2 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.3 EKG19038.1 - 0.094 12.4 0.3 6.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like EMP24_GP25L PF01105.19 EKG19039.1 - 4e-47 160.3 1.5 4.6e-47 160.0 1.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TPR_11 PF13414.1 EKG19040.1 - 4.9e-34 115.8 4.1 1.4e-06 27.8 0.0 6.8 6 1 0 6 6 6 5 TPR repeat TPR_2 PF07719.12 EKG19040.1 - 1.1e-27 93.6 3.3 0.00029 20.5 0.1 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EKG19040.1 - 2.5e-27 93.3 0.7 2.3e-05 23.8 0.4 9.5 10 0 0 10 10 10 6 Tetratricopeptide repeat Apc3 PF12895.2 EKG19040.1 - 3.8e-25 87.8 4.3 3.8e-19 68.6 0.0 5.4 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EKG19040.1 - 1.1e-22 80.1 3.0 1.1e-06 29.0 0.2 6.5 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EKG19040.1 - 3.3e-21 74.9 8.8 6.8e-07 29.1 0.0 8.1 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EKG19040.1 - 1.1e-17 64.1 4.7 0.19 12.0 0.0 8.0 4 2 6 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKG19040.1 - 3.4e-15 55.1 9.3 0.014 15.9 0.1 9.2 4 3 4 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKG19040.1 - 4e-15 54.3 0.0 0.009 15.7 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EKG19040.1 - 1.3e-09 37.9 3.4 0.91 10.1 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG19040.1 - 2e-09 36.5 13.0 0.029 14.1 0.0 8.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKG19040.1 - 4.2e-07 29.6 0.1 7.5 7.0 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 EKG19040.1 - 9.7e-07 28.5 8.7 0.0016 18.2 0.1 6.1 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKG19040.1 - 0.00011 22.0 14.6 0.056 13.3 0.5 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EKG19040.1 - 0.00016 20.8 3.3 0.28 10.2 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EKG19040.1 - 0.00067 19.8 5.4 1.3 9.6 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 EKG19040.1 - 0.0033 17.3 10.2 0.011 15.7 0.0 5.1 6 1 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKG19040.1 - 0.012 15.4 7.5 21 5.0 0.0 5.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF572 PF04502.8 EKG19041.1 - 1.3e-75 254.6 14.0 1.5e-75 254.4 9.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.6 EKG19041.1 - 0.078 12.5 1.1 3.2 7.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) Benyvirus_14KDa PF07255.6 EKG19041.1 - 0.081 12.7 0.3 0.2 11.5 0.2 1.6 1 1 0 1 1 1 0 Benyvirus 14KDa protein zinc_ribbon_5 PF13719.1 EKG19041.1 - 0.14 11.7 0.6 13 5.4 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EKG19041.1 - 0.15 11.3 0.4 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EKG19041.1 - 0.19 12.0 3.9 4.9 7.5 1.2 2.8 2 1 1 3 3 3 0 Restriction alleviation protein Lar Sugar_tr PF00083.19 EKG19043.1 - 8.4e-79 265.2 16.1 9.5e-79 265.0 11.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG19043.1 - 3.9e-17 62.0 17.9 6.8e-12 44.7 4.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EKG19043.1 - 0.00054 19.9 2.8 0.079 13.0 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) MFS_2 PF13347.1 EKG19043.1 - 0.86 7.9 23.9 0.13 10.6 1.8 3.2 2 2 1 3 3 3 0 MFS/sugar transport protein Sugar_tr PF00083.19 EKG19044.1 - 0.00016 20.3 0.1 0.00019 20.1 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1996 PF09362.5 EKG19045.1 - 3.2e-60 203.7 0.8 5.2e-60 203.0 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EKG19045.1 - 1.2e-15 57.1 8.9 1.2e-15 57.1 6.2 2.3 2 0 0 2 2 2 1 WSC domain GST_C PF00043.20 EKG19046.1 - 1.3e-11 44.2 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EKG19046.1 - 3.8e-08 33.0 4.4 6.1e-08 32.4 0.5 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG19046.1 - 1.3e-05 25.6 0.0 2.8e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MTHFR PF02219.12 EKG19047.1 - 8.5e-102 340.1 0.0 2.1e-101 338.7 0.0 1.6 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase DUF3072 PF11272.3 EKG19047.1 - 0.058 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) PQ-loop PF04193.9 EKG19048.1 - 4.6e-38 128.5 14.2 3.9e-20 71.1 0.7 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF3087 PF11286.3 EKG19048.1 - 0.082 12.1 0.1 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) TPR_11 PF13414.1 EKG19049.1 - 1.4e-11 43.9 0.7 3.2e-10 39.4 0.0 2.9 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 EKG19049.1 - 7.7e-06 25.5 0.1 2.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain TPR_1 PF00515.23 EKG19049.1 - 1.3e-05 24.6 0.2 1.6 8.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat DnaJ PF00226.26 EKG19049.1 - 0.0093 15.6 0.1 0.0093 15.6 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 EKG19049.1 - 0.0097 15.7 13.5 0.36 10.8 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPP_enzyme_C PF02775.16 EKG19049.1 - 0.069 12.7 0.0 3.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1688 PF07958.6 EKG19050.1 - 1.2e-183 610.3 0.0 1.4e-183 610.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 EKG19051.1 - 2.3e-82 275.6 0.4 2.8e-82 275.3 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EKG19051.1 - 0.00016 20.9 0.1 0.0005 19.3 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EKG19051.1 - 0.00031 20.1 0.0 0.00051 19.4 0.0 1.4 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 EKG19051.1 - 0.0012 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EKG19051.1 - 0.0035 17.8 0.0 0.0084 16.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Atrophin-1 PF03154.10 EKG19052.1 - 1.3 7.0 15.3 1.5 6.8 10.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family PLDc_2 PF13091.1 EKG19053.1 - 2.7e-22 78.8 0.0 3.4e-10 39.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 EKG19053.1 - 0.00026 20.0 0.0 0.057 12.3 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB PLDc PF00614.17 EKG19053.1 - 0.0013 18.4 0.6 0.031 14.0 0.1 2.4 2 0 0 2 2 2 1 Phospholipase D Active site motif Dioxygenase_C PF00775.16 EKG19055.1 - 0.041 13.1 0.3 0.098 11.9 0.2 1.6 1 1 0 1 1 1 0 Dioxygenase NUDIX_2 PF13869.1 EKG19056.1 - 3.6e-54 182.9 0.0 4.1e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Fungal_trans PF04082.13 EKG19057.1 - 7.7e-06 24.9 0.0 1.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG19057.1 - 9.2e-05 22.2 12.2 0.00021 21.1 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WW PF00397.21 EKG19058.1 - 6.1e-07 29.1 3.0 1.3e-06 28.1 2.1 1.6 1 0 0 1 1 1 1 WW domain DUF1970 PF09301.5 EKG19058.1 - 0.032 14.2 0.3 0.062 13.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Sporozoite_P67 PF05642.6 EKG19058.1 - 0.81 7.4 4.8 1.2 6.9 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_2 PF12796.2 EKG19059.1 - 6.6e-14 52.0 3.5 2.2e-10 40.7 0.4 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG19059.1 - 6e-12 45.7 0.0 1.6e-05 25.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG19059.1 - 1e-11 43.8 2.2 8.4e-07 28.6 0.3 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 EKG19059.1 - 3.8e-11 42.2 7.2 1.8e-07 30.6 1.4 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EKG19059.1 - 4.2e-09 36.3 4.7 4.7e-06 26.6 0.9 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DEAD PF00270.24 EKG19061.1 - 2.6e-40 137.6 0.3 5.9e-40 136.5 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG19061.1 - 2.8e-29 100.7 0.2 5.6e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EKG19061.1 - 0.0017 18.0 0.2 0.0041 16.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EKG19061.1 - 0.013 15.1 0.4 0.03 13.8 0.3 1.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EKG19061.1 - 0.032 13.9 0.2 0.12 12.1 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain ResIII PF04851.10 EKG19061.1 - 0.035 13.9 0.1 0.075 12.8 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EKG19061.1 - 0.077 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_11 PF13086.1 EKG19061.1 - 0.099 12.2 0.3 0.14 11.7 0.2 1.5 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.20 EKG19061.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_22 PF13401.1 EKG19061.1 - 0.14 12.3 0.6 0.65 10.1 0.4 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 EKG19062.1 - 1.4e-69 233.6 0.4 1.4e-69 233.6 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EKG19062.1 - 0.00012 21.5 2.4 0.00034 20.1 1.7 1.9 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EKG19062.1 - 0.00074 19.6 5.3 0.022 14.9 2.6 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-LYAR PF08790.6 EKG19062.1 - 0.0016 18.0 0.7 0.0016 18.0 0.5 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.2 EKG19062.1 - 0.022 14.8 1.9 0.086 12.9 0.1 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Eaf7 PF07904.8 EKG19062.1 - 0.067 13.1 0.4 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 DUF951 PF06107.6 EKG19062.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-C2H2_jaz PF12171.3 EKG19062.1 - 1.3 9.3 14.3 0.19 11.8 5.3 2.8 2 2 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 EKG19062.1 - 1.6 8.4 8.7 0.08 12.6 0.7 2.9 4 0 0 4 4 4 0 DBF zinc finger DUF1996 PF09362.5 EKG19063.1 - 5.9e-79 265.0 0.2 8.3e-79 264.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BCS1_N PF08740.6 EKG19064.1 - 6.8e-39 133.4 0.1 1.1e-38 132.7 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EKG19064.1 - 5.2e-20 71.9 0.0 2.8e-17 63.1 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG19064.1 - 1.4e-05 25.9 0.0 4.9e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EKG19064.1 - 0.0014 17.7 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKG19064.1 - 0.0029 17.6 0.2 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EKG19064.1 - 0.0051 16.2 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EKG19064.1 - 0.009 16.3 0.4 0.065 13.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKG19064.1 - 0.027 14.1 0.0 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EKG19064.1 - 0.028 13.8 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 EKG19064.1 - 0.049 13.2 1.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Polyoma_lg_T_C PF06431.6 EKG19064.1 - 0.051 12.2 0.0 0.11 11.1 0.0 1.5 1 1 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_22 PF13401.1 EKG19064.1 - 0.055 13.6 0.0 0.33 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKG19064.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.19 EKG19065.1 - 5.2e-09 36.0 0.0 8.8e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG19065.1 - 2.6e-07 30.7 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG19065.1 - 1.8e-06 27.8 0.0 3.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG19065.1 - 3.4e-06 27.1 0.1 1.4e-05 25.2 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG19065.1 - 0.0085 15.8 0.0 0.024 14.3 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein 4HBT_3 PF13622.1 EKG19066.1 - 5 6.7 6.5 7.6 6.1 4.5 1.5 1 1 0 1 1 1 0 Thioesterase-like superfamily ATP-synt_ab PF00006.20 EKG19067.1 - 2.4e-29 102.3 0.0 3.6e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EKG19067.1 - 5.1e-10 39.4 0.6 1.3e-09 38.0 0.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 EKG19067.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EKG19068.1 - 1.3e-70 237.2 0.0 2.2e-70 236.5 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EKG19068.1 - 1.6e-18 67.2 0.1 2.6e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain Dynamin_N PF00350.18 EKG19069.1 - 1.8e-57 193.7 0.1 2.6e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EKG19069.1 - 2e-18 66.2 0.0 3.3e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EKG19069.1 - 4.9e-06 26.4 0.3 6e-05 22.9 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKG19069.1 - 0.0094 16.4 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EKG19069.1 - 0.011 14.9 0.1 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B MobB PF03205.9 EKG19069.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ferric_reduct PF01794.14 EKG19070.1 - 5.4e-16 58.8 10.6 5.4e-16 58.8 7.4 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component HRXXH PF13933.1 EKG19071.1 - 8.1e-104 346.3 0.0 1.4e-103 345.6 0.0 1.3 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 EKG19071.1 - 0.028 14.9 0.3 0.062 13.8 0.1 1.7 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Zip PF02535.17 EKG19072.1 - 1.4e-26 93.2 10.1 5.5e-21 74.8 1.7 3.8 4 1 0 4 4 4 2 ZIP Zinc transporter DUF3914 PF13053.1 EKG19073.1 - 0.012 15.7 1.8 0.021 14.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Amidohydro_5 PF13594.1 EKG19074.1 - 3.2e-14 52.4 0.0 8.9e-14 51.0 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG19074.1 - 1.2e-05 25.1 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG19074.1 - 0.0016 18.5 0.0 0.022 14.7 0.0 2.2 1 1 1 2 2 2 1 Amidohydrolase DUF4133 PF13571.1 EKG19075.1 - 2.3 8.4 6.9 0.26 11.5 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) Glyco_hydro_71 PF03659.9 EKG19076.1 - 3.6e-121 404.2 0.4 4.2e-121 404.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4126 PF13548.1 EKG19077.1 - 4.5 6.6 11.4 9.1 5.6 7.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) Aldedh PF00171.17 EKG19080.1 - 2.8e-152 507.3 1.1 3.1e-152 507.1 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EKG19080.1 - 0.07 12.3 0.0 5.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) AA_permease PF00324.16 EKG19081.1 - 1.1e-07 30.6 3.9 1.3e-07 30.3 2.7 1.1 1 0 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.19 EKG19082.1 - 2.3e-12 46.7 0.0 2.7e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Fungal_trans PF04082.13 EKG19083.1 - 4.6e-15 55.1 0.2 8.4e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.6 EKG19084.1 - 2.2e-23 82.9 0.0 3e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SUKH-3 PF14433.1 EKG19085.1 - 0.04 13.6 0.0 0.076 12.8 0.0 1.4 1 1 0 1 1 1 0 SUKH-3 immunity protein PhyH PF05721.8 EKG19085.1 - 0.065 13.2 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) His_Phos_1 PF00300.17 EKG19086.1 - 1.2e-20 74.1 0.0 1.6e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FAA_hydrolase PF01557.13 EKG19087.1 - 3.8e-09 36.3 0.0 4.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PhyH PF05721.8 EKG19088.1 - 0.031 14.2 0.1 0.051 13.6 0.1 1.6 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) NDK PF00334.14 EKG19089.1 - 1.1e-54 183.9 0.0 1.2e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF1446 PF07287.6 EKG19089.1 - 0.05 12.0 0.0 0.065 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) NUFIP1 PF10453.4 EKG19089.1 - 0.083 12.4 0.1 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Glyco_hydro_31 PF01055.21 EKG19090.1 - 5.1e-151 503.4 6.2 6.9e-151 503.0 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG19090.1 - 1e-24 86.1 0.1 4.3e-24 84.1 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Tim17 PF02466.14 EKG19091.1 - 2e-49 166.8 9.0 3.1e-49 166.2 6.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.4 EKG19091.1 - 0.42 10.8 11.8 1.6 8.9 1.9 3.3 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 Aph-1 PF06105.7 EKG19091.1 - 0.65 9.2 3.5 0.78 8.9 0.6 2.0 1 1 0 2 2 2 0 Aph-1 protein Gly-zipper_Omp PF13488.1 EKG19091.1 - 2.2 7.9 17.4 1 9.0 5.0 2.9 3 0 0 3 3 3 0 Glycine zipper tRNA_int_endo PF01974.12 EKG19092.1 - 7.3e-20 70.5 0.2 2e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EKG19092.1 - 3.4e-09 36.1 0.1 1.1e-05 24.9 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Scramblase PF03803.10 EKG19093.1 - 1.4e-47 161.5 0.0 1.5e-23 83.0 0.0 2.9 2 1 0 2 2 2 2 Scramblase UQ_con PF00179.21 EKG19094.1 - 8e-52 174.3 0.0 9e-52 174.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG19094.1 - 0.1 12.3 0.1 0.2 11.4 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Ribosomal_L27 PF01016.14 EKG19095.1 - 8.2e-27 92.8 0.2 1.6e-26 91.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein DUF165 PF02592.10 EKG19096.1 - 0.025 14.7 1.2 0.025 14.7 0.9 2.5 3 0 0 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 DUF4079 PF13301.1 EKG19096.1 - 0.033 14.2 4.6 0.2 11.6 3.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2975 PF11188.3 EKG19096.1 - 1.9 8.1 8.3 4.6 6.9 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) SdpI PF13630.1 EKG19096.1 - 2.1 8.0 6.2 3.2 7.5 0.2 2.7 2 0 0 2 2 2 0 SdpI/YhfL protein family POT1 PF02765.12 EKG19098.1 - 2.8e-07 30.5 0.0 5.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FTH PF01827.22 EKG19101.1 - 0.074 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 FTH domain Cupin_2 PF07883.6 EKG19102.1 - 1.8e-08 33.7 0.0 3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EKG19102.1 - 0.031 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF4048 PF13257.1 EKG19105.1 - 1.4e-31 110.0 15.7 1.5e-28 100.1 5.8 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4048) TPD52 PF04201.10 EKG19105.1 - 0.058 13.1 0.1 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Tumour protein D52 family Pkinase PF00069.20 EKG19106.1 - 2.4e-69 233.3 0.0 3.4e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19106.1 - 1e-45 155.8 0.0 1.5e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG19106.1 - 0.0002 20.4 0.0 0.00041 19.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG19106.1 - 0.024 14.3 0.0 9 5.9 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family CorA PF01544.13 EKG19107.1 - 3e-09 36.3 0.0 3e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Glyco_hydro_16 PF00722.16 EKG19108.1 - 2.9e-08 33.2 0.0 6.3e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Abhydrolase_6 PF12697.2 EKG19110.1 - 2.6e-34 119.0 0.6 3.2e-34 118.8 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG19110.1 - 1.7e-18 66.7 0.0 2.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG19110.1 - 2.5e-18 66.4 0.1 4.6e-18 65.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EKG19110.1 - 2.2e-05 23.0 0.0 3.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EKG19110.1 - 2.8e-05 23.8 0.0 8.3e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EKG19110.1 - 0.0058 15.5 0.1 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF1057 PF06342.7 EKG19110.1 - 0.0059 15.4 0.0 0.0089 14.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.16 EKG19110.1 - 0.011 14.9 0.0 0.082 12.1 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2305 PF10230.4 EKG19110.1 - 0.014 14.7 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Chlorophyllase PF07224.6 EKG19110.1 - 0.016 14.0 0.0 0.21 10.3 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase Ser_hydrolase PF06821.8 EKG19110.1 - 0.026 14.1 0.2 0.026 14.1 0.1 1.7 2 0 0 2 2 2 0 Serine hydrolase Lipase_3 PF01764.20 EKG19110.1 - 0.096 12.3 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1757 PF08560.5 EKG19112.1 - 0.0022 17.7 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) DUF1546 PF07571.8 EKG19113.1 - 3e-26 91.3 0.0 6e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EKG19113.1 - 6.4e-26 90.0 0.1 1.5e-25 88.9 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EKG19113.1 - 1.4e-05 25.1 0.0 0.00053 20.0 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EKG19113.1 - 0.00027 20.9 0.1 0.00065 19.7 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AMP-binding PF00501.23 EKG19115.1 - 7.4e-33 113.5 0.1 2.4e-32 111.8 0.1 1.7 1 1 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EKG19115.1 - 2.7e-13 49.9 0.1 4.9e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site MIP PF00230.15 EKG19117.1 - 1.2e-47 162.3 16.4 1.5e-47 161.9 11.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein FMN_dh PF01070.13 EKG19118.1 - 3.2e-120 401.2 0.0 3.7e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EKG19118.1 - 3.4e-05 22.9 1.1 0.00036 19.5 0.3 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EKG19118.1 - 0.00041 19.5 0.7 0.00058 19.1 0.5 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EKG19118.1 - 0.0057 15.6 0.2 0.0085 15.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EKG19118.1 - 0.014 14.4 0.6 0.92 8.5 0.1 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EKG19118.1 - 0.059 12.6 0.5 3.7 6.7 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein CN_hydrolase PF00795.17 EKG19119.1 - 2.6e-30 105.1 0.1 3.4e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 EKG19120.1 - 1.7e-41 142.1 53.3 2.7e-41 141.4 35.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1237 PF06824.6 EKG19121.1 - 9.8e-171 568.0 0.0 1.1e-170 567.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) MSA-2c PF12238.3 EKG19122.1 - 0.54 9.8 1.7 0.81 9.3 1.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Strabismus PF06638.6 EKG19122.1 - 1.8 6.7 4.3 21 3.2 2.5 2.0 2 0 0 2 2 2 0 Strabismus protein CoA_transf_3 PF02515.12 EKG19124.1 - 2.6e-23 82.2 0.2 3.5e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III SRP54 PF00448.17 EKG19125.1 - 8.6e-76 253.7 0.2 1.6e-75 252.9 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EKG19125.1 - 1.2e-24 86.5 4.2 1.2e-24 86.5 2.9 4.2 3 1 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 EKG19125.1 - 6.1e-16 58.2 0.3 1.8e-15 56.7 0.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EKG19125.1 - 1.7e-07 31.1 0.1 5.9e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EKG19125.1 - 5.3e-07 29.2 0.0 1.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EKG19125.1 - 1.2e-05 24.9 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EKG19125.1 - 0.00028 20.3 0.0 0.00083 18.8 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 EKG19125.1 - 0.00039 20.5 0.1 0.0011 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKG19125.1 - 0.00084 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 EKG19125.1 - 0.0024 17.0 1.8 1.7 7.8 0.1 2.8 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 EKG19125.1 - 0.0042 17.9 0.0 0.011 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EKG19125.1 - 0.013 15.4 0.0 2.5 8.0 0.0 2.6 1 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EKG19125.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EKG19125.1 - 0.016 14.5 0.0 0.037 13.3 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.12 EKG19125.1 - 0.02 14.4 0.1 0.089 12.3 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EKG19125.1 - 0.037 14.3 0.0 0.13 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG19125.1 - 0.04 13.8 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PTPlike_phytase PF14566.1 EKG19125.1 - 0.061 13.3 0.0 9 6.3 0.0 3.6 4 0 0 4 4 4 0 Inositol hexakisphosphate VirE PF05272.6 EKG19125.1 - 0.073 12.5 0.2 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E Zeta_toxin PF06414.7 EKG19125.1 - 0.082 11.9 0.0 0.33 10.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 EKG19125.1 - 0.086 11.4 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain VirC1 PF07015.6 EKG19125.1 - 0.086 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 VirC1 protein AAA_28 PF13521.1 EKG19125.1 - 0.15 12.0 0.1 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Rrp15p PF07890.7 EKG19126.1 - 8.1e-38 129.4 9.8 8.1e-38 129.4 6.8 2.5 3 0 0 3 3 3 1 Rrp15p SBP_bac_3 PF00497.15 EKG19127.1 - 0.00044 19.5 0.0 0.0024 17.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.6 EKG19127.1 - 0.0049 16.4 0.0 0.41 10.1 0.0 2.9 1 1 1 2 2 2 1 NMT1/THI5 like DUF3834 PF12916.2 EKG19127.1 - 0.022 13.7 0.2 0.07 12.1 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3834) SBP_bac_11 PF13531.1 EKG19127.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein FMO-like PF00743.14 EKG19128.1 - 1.5e-42 145.5 0.0 1.8e-23 82.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EKG19128.1 - 2e-14 54.1 0.0 2.5e-13 50.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG19128.1 - 3.5e-09 36.8 0.0 5.2e-05 23.2 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG19128.1 - 1.4e-08 34.7 0.3 8.9e-06 25.5 0.2 3.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EKG19128.1 - 1.4e-07 30.8 0.2 7.2e-05 21.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EKG19128.1 - 2.6e-06 26.7 0.0 2e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EKG19128.1 - 3.3e-06 27.0 0.0 9.2e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG19128.1 - 0.0011 18.0 0.1 0.94 8.3 0.0 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase DJ-1_PfpI PF01965.19 EKG19128.1 - 0.022 14.2 0.1 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 DJ-1/PfpI family Semialdhyde_dh PF01118.19 EKG19128.1 - 0.046 14.0 0.0 0.75 10.1 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Metallophos PF00149.23 EKG19129.1 - 1.5e-41 142.0 0.5 2.2e-41 141.4 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adap_comp_sub PF00928.16 EKG19131.1 - 2.3e-91 305.5 0.0 3.2e-91 305.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EKG19131.1 - 1.6e-09 37.6 0.2 2.7e-09 36.8 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fer2 PF00111.22 EKG19132.1 - 1.6e-15 56.6 1.0 2.1e-15 56.2 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 EKG19132.1 - 0.12 12.2 1.4 0.44 10.3 0.9 1.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EKG19133.1 - 2.3e-13 49.6 0.9 0.0036 16.9 0.0 5.6 4 1 0 4 4 4 4 Mitochondrial carrier protein DUF3328 PF11807.3 EKG19134.1 - 0.0038 16.9 0.5 0.0038 16.9 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) Fungal_trans PF04082.13 EKG19137.1 - 5.1e-17 61.6 0.0 7.8e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG19137.1 - 1.8e-06 27.7 10.3 3.2e-06 26.9 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSP1_C PF07462.6 EKG19137.1 - 0.38 9.0 0.7 0.55 8.5 0.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3337 PF11816.3 EKG19138.1 - 1.1e-90 304.4 0.0 3.9e-86 289.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EKG19138.1 - 6.7e-11 41.6 5.7 3.9e-07 29.6 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat ABC2_membrane PF01061.19 EKG19140.1 - 6.8e-83 276.9 51.9 5.2e-44 149.9 11.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EKG19140.1 - 4.6e-37 127.3 0.0 1.9e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG19140.1 - 9.7e-30 102.2 9.8 9e-26 89.5 0.0 3.5 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EKG19140.1 - 1e-07 31.3 36.6 0.00025 20.1 7.7 2.9 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EKG19140.1 - 2.9e-06 26.8 5.0 0.0012 18.3 1.4 2.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EKG19140.1 - 3e-06 26.6 3.5 0.001 18.5 0.3 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EKG19140.1 - 0.0001 22.3 1.6 0.023 14.6 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EKG19140.1 - 0.00013 21.8 0.9 0.047 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EKG19140.1 - 0.00044 19.4 0.7 0.027 13.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKG19140.1 - 0.001 19.2 0.1 0.19 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EKG19140.1 - 0.0012 18.1 0.1 0.58 9.3 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EKG19140.1 - 0.0023 18.7 0.2 0.47 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.1 EKG19140.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal NACHT PF05729.7 EKG19140.1 - 0.015 14.9 1.3 1.7 8.2 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EKG19140.1 - 0.016 15.4 1.3 0.6 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EKG19140.1 - 0.017 15.1 4.2 0.32 10.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 EKG19140.1 - 0.024 14.8 0.7 11 6.2 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EKG19140.1 - 0.026 14.8 1.5 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EKG19140.1 - 0.089 12.5 4.2 6.6 6.5 0.8 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 EKG19140.1 - 0.2 11.0 2.1 6.3 6.1 0.1 2.6 3 0 0 3 3 3 0 AAA-like domain UPF0079 PF02367.12 EKG19140.1 - 0.3 10.7 1.4 8.1 6.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EKG19140.1 - 0.32 10.6 0.1 14 5.2 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 EKG19140.1 - 0.35 10.4 0.3 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EKG19140.1 - 0.45 9.9 4.7 0.22 10.9 0.6 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.1 EKG19140.1 - 0.9 8.5 0.0 1.4 7.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EKG19140.1 - 1.4 8.8 5.8 0.15 12.0 0.5 1.9 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EKG19140.1 - 1.7 7.4 3.4 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Glyco_hydro_43 PF04616.9 EKG19142.1 - 7.3e-71 238.5 0.6 2.3e-70 236.9 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 DUF1349 PF07081.6 EKG19142.1 - 0.0058 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) SBP_bac_11 PF13531.1 EKG19142.1 - 0.05 13.2 0.0 0.36 10.4 0.0 2.0 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein MFS_1 PF07690.11 EKG19143.1 - 1.4e-33 116.0 29.9 1.4e-33 116.0 20.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19143.1 - 9.4e-10 37.6 7.4 9.4e-10 37.6 5.2 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EKG19143.1 - 2.4e-05 22.7 2.4 2.4e-05 22.7 1.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG19144.1 - 3.2e-22 78.7 21.1 3.2e-22 78.7 14.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19144.1 - 0.0021 16.7 12.1 0.0021 16.7 8.4 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4473 PF14747.1 EKG19144.1 - 0.22 11.7 0.0 6.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Glyco_hydro_32N PF00251.15 EKG19146.1 - 0.00072 19.0 0.0 0.0016 17.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 EKG19146.1 - 0.0019 17.3 3.2 0.012 14.7 2.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 CorA PF01544.13 EKG19148.1 - 2.5e-06 26.7 1.6 4.7e-06 25.8 0.1 1.9 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Flp_Fap PF04964.9 EKG19148.1 - 0.027 14.0 0.9 0.06 12.9 0.3 1.8 2 0 0 2 2 2 0 Flp/Fap pilin component Glyco_hydro_61 PF03443.9 EKG19150.1 - 1.5e-51 175.2 0.0 2.3e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EKG19150.1 - 1.9e-12 46.6 8.5 3.7e-12 45.6 5.9 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain A2M_N PF01835.14 EKG19150.1 - 0.039 14.2 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 MG2 domain Glyco_hydro_43 PF04616.9 EKG19152.1 - 1.4e-59 201.5 1.1 5.3e-59 199.6 1.4 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 EKG19153.1 - 1.2e-16 60.4 35.9 1.7e-10 40.1 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LIM PF00412.17 EKG19154.1 - 1.5e-26 92.2 31.6 5.4e-10 39.2 2.9 4.0 4 0 0 4 4 4 3 LIM domain Aldo_ket_red PF00248.16 EKG19155.1 - 5.8e-58 195.9 0.0 6.6e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.1 EKG19156.1 - 4.8e-07 29.7 0.6 4.8e-07 29.7 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG19156.1 - 1.8e-05 24.7 3.5 0.00035 20.6 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG19156.1 - 8.9e-05 22.6 0.2 8.9e-05 22.6 0.2 3.0 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EKG19156.1 - 0.12 12.3 0.1 23 5.0 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG19156.1 - 0.17 12.0 0.7 3.5 7.8 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Kinesin PF00225.18 EKG19157.1 - 5.2e-92 308.1 0.0 3.3e-91 305.4 0.0 2.5 1 0 0 1 1 1 1 Kinesin motor domain ABC_tran_2 PF12848.2 EKG19157.1 - 0.0079 16.0 1.8 0.0079 16.0 1.3 10.9 8 3 5 14 14 14 1 ABC transporter DUF904 PF06005.7 EKG19157.1 - 0.029 14.6 0.0 0.029 14.6 0.0 13.5 7 5 5 12 12 12 0 Protein of unknown function (DUF904) DENN PF02141.16 EKG19159.1 - 8.5e-40 136.4 0.0 1.5e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EKG19159.1 - 7.3e-05 22.6 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EKG19159.1 - 0.0092 16.3 6.1 0.0092 16.3 4.2 2.9 2 1 0 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ADIP PF11559.3 EKG19159.1 - 0.4 10.5 19.6 1.2 9.0 5.6 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Dfp1_Him1_M PF08630.5 EKG19159.1 - 0.8 9.5 5.0 9.1 6.0 3.2 2.3 2 0 0 2 2 2 0 Dfp1/Him1, central region CENP-F_leu_zip PF10473.4 EKG19159.1 - 1.9 8.3 23.3 0.14 12.0 5.4 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EKG19159.1 - 5.4 6.5 24.4 0.59 9.6 9.1 2.5 1 1 1 2 2 2 0 IncA protein DUF2570 PF10828.3 EKG19159.1 - 7.2 6.2 12.4 4.3 6.9 6.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Epimerase PF01370.16 EKG19162.1 - 8e-06 25.4 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG19162.1 - 0.011 14.5 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain MFS_1 PF07690.11 EKG19164.1 - 0.019 13.6 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily adh_short_C2 PF13561.1 EKG19166.1 - 2.2e-31 109.4 0.8 2.7e-31 109.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG19166.1 - 8.9e-31 107.0 0.5 1.4e-30 106.4 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19166.1 - 2.3e-12 46.9 0.2 3.9e-12 46.1 0.1 1.3 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EKG19166.1 - 0.0021 17.8 1.4 0.0048 16.6 0.7 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EKG19166.1 - 0.011 15.1 0.2 0.044 13.2 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EKG19166.1 - 0.021 14.6 0.5 0.056 13.2 0.1 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glyco_trans_4_4 PF13579.1 EKG19166.1 - 0.029 14.4 0.1 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Saccharop_dh PF03435.13 EKG19166.1 - 0.03 13.3 0.1 0.066 12.1 0.1 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 EKG19166.1 - 0.099 11.7 0.3 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EKG19166.1 - 0.19 11.3 2.8 0.55 9.8 0.3 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mid2 PF04478.7 EKG19167.1 - 9.5e-05 21.8 0.0 0.00023 20.6 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EKG19167.1 - 0.013 14.8 0.7 0.025 13.8 0.5 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EKG19167.1 - 0.03 12.5 0.0 0.076 11.2 0.0 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EKG19167.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 EKG19167.1 - 0.049 13.6 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Syndecan PF01034.15 EKG19167.1 - 0.095 12.3 0.3 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain KAR9 PF08580.5 EKG19167.1 - 4.1 5.5 12.5 5.2 5.2 8.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 RNB PF00773.14 EKG19168.1 - 4.6e-94 315.3 0.1 6.5e-94 314.8 0.1 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EKG19168.1 - 1.3e-09 38.2 1.3 3.3e-09 36.9 0.1 2.3 3 0 0 3 3 3 1 PIN domain DUF3958 PF13125.1 EKG19168.1 - 0.1 12.5 1.5 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) CRC_subunit PF08624.5 EKG19170.1 - 5.4e-55 185.1 0.0 9.1e-55 184.3 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AT_hook PF02178.14 EKG19170.1 - 0.092 12.4 6.2 0.38 10.5 4.3 2.2 1 0 0 1 1 1 0 AT hook motif V-ATPase_H_N PF03224.9 EKG19173.1 - 2e-77 260.4 2.8 2.6e-77 260.0 2.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EKG19173.1 - 9.4e-39 132.0 0.0 2.7e-38 130.5 0.0 1.8 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_EZ PF13513.1 EKG19173.1 - 0.067 13.6 2.0 29 5.3 0.0 4.1 2 1 1 3 3 3 0 HEAT-like repeat DUF619 PF04768.8 EKG19173.1 - 0.094 12.1 0.1 12 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF619) Phage_int_SAM_1 PF02899.12 EKG19173.1 - 2.3 8.4 5.6 3.3 7.9 0.1 3.5 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain CAP_GLY PF01302.20 EKG19174.1 - 3e-21 74.8 0.2 5.1e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EKG19174.1 - 4.9e-13 48.3 10.0 0.0014 18.1 1.7 5.1 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG19174.1 - 2.1e-08 33.8 11.6 1.1e-05 25.0 0.2 4.7 4 2 3 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 EKG19174.1 - 5.8e-05 22.7 2.7 16 5.9 0.1 6.2 7 0 0 7 7 7 1 Leucine Rich repeat LRR_9 PF14580.1 EKG19174.1 - 9.5e-05 22.0 0.2 0.27 10.7 0.1 3.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 EKG19174.1 - 0.00031 20.4 10.2 11 6.7 0.0 6.9 8 0 0 8 8 8 1 Leucine rich repeat LRR_1 PF00560.28 EKG19174.1 - 0.00048 19.7 4.9 17 5.9 0.1 6.1 5 1 1 6 6 6 1 Leucine Rich Repeat Abhydro_lipase PF04083.11 EKG19174.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region p450 PF00067.17 EKG19175.1 - 3e-74 250.2 0.0 2.4e-73 247.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 FAD_binding_1 PF00667.15 EKG19175.1 - 3.5e-37 127.9 0.0 7.2e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EKG19175.1 - 1.6e-22 80.0 0.0 3.4e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EKG19175.1 - 4.8e-15 56.0 0.0 1.2e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain P2_Phage_GpR PF06891.6 EKG19175.1 - 0.084 12.6 0.0 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) Flavodoxin_5 PF12724.2 EKG19175.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain CHCH PF06747.8 EKG19176.1 - 9.1e-05 22.2 2.4 0.00014 21.6 1.7 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EKG19176.1 - 0.0016 18.4 3.1 0.0034 17.3 2.2 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 EKG19176.1 - 0.41 10.5 3.1 18 5.2 0.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX17 PF05051.8 EKG19176.1 - 5.8 7.0 7.0 4.7 7.3 0.1 2.4 2 1 1 3 3 3 0 Cytochrome C oxidase copper chaperone (COX17) HLH PF00010.21 EKG19177.1 - 1.9e-12 46.6 0.0 7.1e-12 44.8 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain Macoilin PF09726.4 EKG19177.1 - 0.36 9.0 3.1 0.89 7.7 2.1 1.6 1 1 0 1 1 1 0 Transmembrane protein Got1 PF04178.7 EKG19178.1 - 7.5e-32 109.9 16.1 9.3e-32 109.6 11.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Claudin_2 PF13903.1 EKG19178.1 - 3 7.5 11.9 2.7 7.6 7.0 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction NPR3 PF03666.8 EKG19180.1 - 2.5e-133 444.9 0.0 1.5e-132 442.3 0.0 2.0 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Mito_carr PF00153.22 EKG19181.1 - 4.3e-72 237.9 1.2 1.5e-25 88.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.6 EKG19181.1 - 0.0038 17.0 2.5 0.27 11.2 0.2 3.0 3 0 0 3 3 3 2 Uperin family Dna2 PF08696.6 EKG19182.1 - 8.3e-70 234.3 0.1 1.7e-69 233.3 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EKG19182.1 - 4.7e-53 179.5 0.0 7.9e-53 178.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG19182.1 - 1.7e-39 135.7 0.3 3e-20 72.8 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 EKG19182.1 - 4.6e-13 49.2 0.0 2.4e-12 46.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EKG19182.1 - 6.8e-11 41.7 2.3 9.4e-11 41.3 0.3 2.3 2 0 0 2 2 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EKG19182.1 - 1.6e-10 41.1 0.2 6.3e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 EKG19182.1 - 7.4e-08 32.2 1.9 0.25 10.8 0.1 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase PDDEXK_1 PF12705.2 EKG19182.1 - 4.7e-07 29.4 0.6 1.3e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Helicase_RecD PF05127.9 EKG19182.1 - 0.00023 20.8 0.0 0.00052 19.6 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EKG19182.1 - 0.00023 20.5 0.1 0.00075 18.8 0.1 1.9 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EKG19182.1 - 0.00065 19.7 2.2 0.0027 17.7 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.17 EKG19182.1 - 0.0013 18.2 0.2 0.0027 17.1 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 EKG19182.1 - 0.003 17.2 0.2 0.0074 15.9 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EKG19182.1 - 0.0037 16.2 0.2 0.12 11.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 EKG19182.1 - 0.0069 16.2 0.3 0.016 15.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 CbiA PF01656.18 EKG19182.1 - 0.019 14.3 0.2 0.056 12.8 0.1 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.9 EKG19182.1 - 0.028 13.3 0.1 0.08 11.8 0.0 1.7 1 1 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.1 EKG19182.1 - 0.043 13.9 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EKG19182.1 - 0.052 13.0 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 EKG19182.1 - 0.086 13.0 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EKG19182.1 - 0.098 12.0 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA-like domain UvrD_C_2 PF13538.1 EKG19182.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.8 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_18 PF13238.1 EKG19182.1 - 3.1 8.1 5.4 2.1 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain Mito_carr PF00153.22 EKG19183.1 - 2.6e-60 200.1 3.1 2.1e-22 78.6 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.9 EKG19184.1 - 5.6e-28 97.6 0.2 9.9e-28 96.8 0.0 1.5 2 0 0 2 2 2 1 MT-A70 AMPKBI PF04739.10 EKG19186.1 - 0.0038 17.0 7.3 2 8.2 1.0 3.7 3 0 0 3 3 3 3 5'-AMP-activated protein kinase beta subunit, interation domain RAB3GAP2_N PF14655.1 EKG19186.1 - 0.23 10.4 0.2 0.44 9.5 0.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Smg4_UPF3 PF03467.10 EKG19187.1 - 1.2e-14 54.7 0.0 1.2e-14 54.7 0.0 2.2 2 0 0 2 2 2 1 Smg-4/UPF3 family Metallophos PF00149.23 EKG19188.1 - 8.9e-40 136.2 0.1 9.5e-34 116.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Zn_clus PF00172.13 EKG19192.1 - 1.6e-05 24.7 9.3 2.5e-05 24.0 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UxaC PF02614.9 EKG19192.1 - 0.02 13.5 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Glucuronate isomerase Prefoldin_2 PF01920.15 EKG19192.1 - 0.12 12.1 0.1 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Prefoldin subunit Metallothio_Pro PF02069.11 EKG19193.1 - 0.11 12.3 0.7 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic metallothionein Fer4_3 PF12798.2 EKG19194.1 - 4.7 8.0 10.5 1.7 9.3 0.9 3.1 2 0 0 2 2 2 0 4Fe-4S binding domain ATP_bind_3 PF01171.15 EKG19195.1 - 6e-38 130.1 0.0 1.5e-37 128.8 0.0 1.6 1 1 0 1 1 1 1 PP-loop family Cpn10 PF00166.16 EKG19196.1 - 1.8e-27 95.0 0.0 2.3e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit WD40 PF00400.27 EKG19198.1 - 4.6e-11 42.1 0.4 0.0046 16.7 0.0 4.8 3 1 0 3 3 3 3 WD domain, G-beta repeat PD40 PF07676.7 EKG19198.1 - 0.00047 19.7 0.0 0.97 9.1 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EKG19198.1 - 0.064 12.5 0.1 12 5.3 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Lactonase PF10282.4 EKG19198.1 - 0.065 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller TPR_11 PF13414.1 EKG19199.1 - 2.2e-11 43.2 4.9 3.6e-11 42.5 0.7 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EKG19199.1 - 8.5e-06 25.1 2.1 0.16 11.5 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKG19199.1 - 7.8e-05 22.5 0.9 7.8e-05 22.5 0.7 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG19199.1 - 0.00015 21.4 3.9 0.16 11.9 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG19199.1 - 0.0011 19.0 1.1 0.0029 17.7 0.7 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EKG19199.1 - 0.0016 18.1 0.1 2.9 7.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKG19199.1 - 0.011 16.0 0.7 0.059 13.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG19199.1 - 0.083 13.5 5.2 2.6 8.9 0.0 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG19199.1 - 2.2 8.9 6.6 93 3.8 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat XAP5 PF04921.9 EKG19200.1 - 1.6e-82 276.6 1.9 2.1e-82 276.2 0.0 1.8 2 0 0 2 2 2 1 XAP5, circadian clock regulator zf-RING_5 PF14634.1 EKG19201.1 - 1.3e-07 31.2 7.2 2.1e-07 30.5 5.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EKG19201.1 - 0.00017 21.3 3.0 0.00033 20.4 2.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKG19201.1 - 0.00026 20.9 4.5 0.00047 20.1 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG19201.1 - 0.0018 17.9 7.6 0.0032 17.0 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Lebercilin PF15619.1 EKG19201.1 - 0.0019 17.6 2.7 0.003 16.9 1.9 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease zf-MIZ PF02891.15 EKG19201.1 - 0.008 15.6 4.7 0.014 14.9 3.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger Tnp_P_element PF12017.3 EKG19201.1 - 0.0093 15.2 0.5 0.016 14.4 0.3 1.3 1 1 0 1 1 1 1 Transposase protein zf-C3HC4_3 PF13920.1 EKG19201.1 - 0.011 15.3 6.4 0.022 14.4 4.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EKG19201.1 - 0.012 15.3 2.5 0.023 14.4 1.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Cut12 PF11500.3 EKG19201.1 - 0.012 15.2 4.2 0.019 14.6 2.9 1.2 1 0 0 1 1 1 0 Spindle pole body formation-associated protein zf-C3HC4_4 PF15227.1 EKG19201.1 - 0.017 14.9 5.7 0.035 13.9 4.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EKG19201.1 - 0.02 14.5 3.4 0.038 13.6 2.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger SPX PF03105.14 EKG19201.1 - 0.023 14.4 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 SPX domain Myosin_tail_1 PF01576.14 EKG19201.1 - 0.034 11.8 6.0 0.047 11.4 4.2 1.2 1 0 0 1 1 1 0 Myosin tail DZR PF12773.2 EKG19201.1 - 0.057 13.2 2.0 0.16 11.7 1.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon APG6 PF04111.7 EKG19201.1 - 0.087 11.8 5.8 0.13 11.3 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Snapin_Pallidin PF14712.1 EKG19201.1 - 0.098 12.9 3.3 0.19 12.0 2.1 1.6 1 1 0 1 1 1 0 Snapin/Pallidin Mito_carr PF00153.22 EKG19201.1 - 0.1 12.2 0.4 0.71 9.6 0.0 2.5 2 1 1 3 3 3 0 Mitochondrial carrier protein EHN PF06441.7 EKG19201.1 - 0.11 12.4 0.0 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Fib_alpha PF08702.5 EKG19201.1 - 0.12 12.5 2.2 0.2 11.7 1.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family C1_4 PF07975.7 EKG19201.1 - 0.16 12.0 4.6 0.64 10.0 2.3 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain FlxA PF14282.1 EKG19201.1 - 1.3 9.0 7.0 1.6 8.7 3.8 1.7 1 1 1 2 2 2 0 FlxA-like protein FYVE PF01363.16 EKG19201.1 - 1.3 8.9 5.4 2.6 8.0 3.8 1.5 1 0 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 EKG19201.1 - 1.9 8.3 6.4 31 4.5 0.0 2.5 1 1 1 2 2 2 0 IBR domain SGL PF08450.7 EKG19202.1 - 0.049 13.0 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region UQ_con PF00179.21 EKG19204.1 - 3.4e-17 62.1 0.0 3.7e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EKG19204.1 - 0.003 17.4 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain Sec7_N PF12783.2 EKG19205.1 - 1.1e-40 138.7 6.7 3.4e-40 137.2 0.0 4.2 5 1 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EKG19205.1 - 1.9e-05 24.0 7.3 0.013 14.9 0.0 5.7 8 0 0 8 8 8 2 Domain of unknown function (DUF1981) Xpo1 PF08389.7 EKG19205.1 - 0.034 14.0 5.2 0.19 11.5 0.1 4.0 4 0 0 4 4 4 0 Exportin 1-like protein NmrA PF05368.8 EKG19207.1 - 3.1e-58 196.7 0.0 3.7e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG19207.1 - 2.9e-13 50.2 0.0 4.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EKG19207.1 - 2.4e-05 23.1 0.0 3.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Oxidored_molyb PF00174.14 EKG19208.1 - 3.6e-49 166.4 0.0 5.8e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EKG19208.1 - 1.2e-24 86.4 2.1 2.2e-24 85.5 1.5 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain RRN3 PF05327.6 EKG19208.1 - 0.12 10.4 0.3 0.16 10.0 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HET PF06985.6 EKG19210.1 - 1.1e-20 74.1 0.0 2.4e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_6 PF13912.1 EKG19210.1 - 0.19 11.6 0.2 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger OB_NTP_bind PF07717.11 EKG19211.1 - 3e-27 94.7 0.0 7.2e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EKG19211.1 - 6.5e-24 83.8 0.1 1.5e-23 82.7 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKG19211.1 - 3.7e-12 45.9 0.0 7.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG19211.1 - 1.2e-06 28.1 0.1 2.9e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKG19211.1 - 1.5e-05 25.1 0.0 5.5e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EKG19211.1 - 0.003 17.0 0.1 0.0076 15.7 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EKG19211.1 - 0.0078 16.0 0.0 5.6 6.7 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EKG19211.1 - 0.0096 15.1 0.0 1.6 7.9 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein AAA_16 PF13191.1 EKG19211.1 - 0.014 15.4 0.0 0.11 12.4 0.0 2.3 1 1 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EKG19211.1 - 0.017 13.9 0.0 0.057 12.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EKG19211.1 - 0.019 14.7 0.1 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.1 EKG19211.1 - 0.038 13.5 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRMT5 PF05185.11 EKG19212.1 - 7.1e-169 562.4 0.0 8.6e-169 562.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EKG19212.1 - 0.057 13.4 0.0 2.7 8.0 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.13 EKG19214.1 - 1.5e-09 37.1 0.3 2.3e-09 36.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG19214.1 - 6.1e-08 32.4 12.7 6.1e-08 32.4 8.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EKG19214.1 - 7.3e-05 22.8 24.5 0.0032 17.6 0.7 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EKG19214.1 - 0.0057 16.8 4.2 0.0057 16.8 2.9 3.7 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 EKG19214.1 - 0.0096 16.2 1.9 0.0096 16.2 1.3 3.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type PyrI_C PF02748.10 EKG19214.1 - 0.022 14.2 0.3 0.022 14.2 0.2 1.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain RRN7 PF11781.3 EKG19214.1 - 1.8 8.1 10.3 2.4 7.7 0.1 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 4HBT PF03061.17 EKG19215.1 - 1.8e-11 44.0 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF1193 PF06702.7 EKG19215.1 - 0.0053 16.1 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) 4HBT_3 PF13622.1 EKG19215.1 - 0.018 14.7 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF1070 PF06376.7 EKG19216.1 - 0.33 10.8 0.2 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1070) Phage_holin PF04688.8 EKG19217.1 - 0.34 10.4 1.5 0.83 9.2 1.0 1.6 1 1 0 1 1 1 0 Phage lysis protein, holin Kelch_1 PF01344.20 EKG19219.1 - 0.035 13.6 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Kelch_4 PF13418.1 EKG19219.1 - 2.1 8.1 7.1 1.1 9.1 0.1 3.5 3 1 0 3 3 3 0 Galactose oxidase, central domain NAD_binding_6 PF08030.7 EKG19220.1 - 1.3e-25 90.0 0.0 1.8e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG19220.1 - 1.9e-19 69.4 0.0 3.7e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EKG19220.1 - 0.008 16.7 0.0 0.28 11.7 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EKG19220.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain MFS_1 PF07690.11 EKG19221.1 - 9.5e-38 129.8 27.2 9.5e-38 129.8 18.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19221.1 - 5e-13 48.4 18.9 6.9e-13 47.9 13.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short PF00106.20 EKG19222.1 - 1.5e-28 99.8 1.6 2.1e-28 99.3 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG19222.1 - 1.2e-22 80.8 0.0 2.3e-22 79.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG19222.1 - 2.8e-11 43.3 1.2 3.9e-11 42.9 0.8 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG19222.1 - 0.019 14.9 4.4 0.1 12.6 0.4 2.3 2 1 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 EKG19222.1 - 0.11 12.1 1.4 0.12 12.0 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FtsL PF04999.8 EKG19223.1 - 0.022 14.4 0.1 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Cell division protein FtsL DUF2188 PF09954.4 EKG19223.1 - 0.18 11.7 2.1 0.35 10.8 1.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) G-patch PF01585.18 EKG19224.1 - 1.5e-08 34.2 1.7 4e-08 32.9 1.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EKG19224.1 - 0.08 12.8 0.6 0.25 11.1 0.4 1.9 1 0 0 1 1 1 0 DExH-box splicing factor binding site DUF92 PF01940.11 EKG19225.1 - 6.7e-61 205.3 11.2 8.9e-61 204.9 7.8 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF3814 PF12769.2 EKG19225.1 - 9.1 6.5 11.8 2.1 8.5 0.9 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3814) ATP-grasp_2 PF08442.5 EKG19226.1 - 3.9e-09 36.1 0.0 5.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EKG19227.1 - 1.6e-18 66.6 0.0 1.6e-15 56.7 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EKG19227.1 - 2.8e-18 66.2 0.0 7.6e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 EKG19227.1 - 1.5e-14 53.8 0.3 3.3e-14 52.7 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 EKG19227.1 - 2.1e-05 24.1 0.0 0.00068 19.2 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Equine_IAV_S2 PF06502.6 EKG19227.1 - 0.083 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein His_Phos_2 PF00328.17 EKG19228.1 - 6.2e-10 38.9 0.0 1.9e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SOBP PF15279.1 EKG19229.1 - 0.009 16.4 2.7 0.01 16.2 1.9 1.1 1 0 0 1 1 1 1 Sine oculis-binding protein CAF-1_p150 PF11600.3 EKG19229.1 - 0.54 9.6 2.8 0.67 9.2 1.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PTCB-BRCT PF12738.2 EKG19230.1 - 2.5e-28 97.7 0.9 1.9e-18 66.0 0.3 4.0 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EKG19230.1 - 2.9e-21 75.4 0.0 4.6e-08 33.1 0.0 5.4 5 0 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain Abhydrolase_6 PF12697.2 EKG19231.1 - 1.4e-24 87.3 0.1 1.1e-23 84.3 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG19231.1 - 0.00037 20.2 0.0 0.0008 19.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG19231.1 - 0.0018 17.8 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Voltage_CLC PF00654.15 EKG19232.1 - 3e-88 296.2 16.5 3e-88 296.2 11.4 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel Choline_kinase PF01633.15 EKG19233.1 - 2.2e-47 161.3 0.0 4.1e-46 157.2 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EKG19233.1 - 3.3e-10 40.1 3.4 1.4e-09 38.0 1.6 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Mito_carr PF00153.22 EKG19234.1 - 7e-23 80.1 0.7 9.2e-17 60.5 0.1 2.9 2 1 0 2 2 2 2 Mitochondrial carrier protein ETRAMP PF09716.5 EKG19235.1 - 0.07 13.0 1.8 0.54 10.2 0.1 2.5 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Gly-zipper_OmpA PF13436.1 EKG19235.1 - 0.14 11.8 9.9 0.38 10.4 0.0 4.1 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_61 PF03443.9 EKG19237.1 - 7.9e-43 146.8 0.1 9.7e-43 146.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CK_II_beta PF01214.13 EKG19239.1 - 4.1e-77 257.8 0.0 7.5e-77 256.9 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EKG19239.1 - 0.00077 20.0 7.9 0.00077 20.0 5.5 2.7 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Nucleoplasmin PF03066.10 EKG19239.1 - 0.2 11.1 13.5 0.29 10.6 5.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin FAM176 PF14851.1 EKG19239.1 - 0.61 9.7 6.6 0.88 9.2 0.9 2.3 2 0 0 2 2 2 0 FAM176 family DUF454 PF04304.8 EKG19240.1 - 0.1 12.6 0.7 0.1 12.6 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF454) zf-H2C2_2 PF13465.1 EKG19241.1 - 5.5e-09 35.8 45.8 3.5e-05 23.8 2.1 7.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2 PF00096.21 EKG19241.1 - 6e-08 32.5 48.3 7.6e-05 22.8 2.3 8.5 8 0 0 8 8 8 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EKG19241.1 - 1.8e-05 24.7 24.3 2.9e-05 24.0 1.4 5.1 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG19241.1 - 2.4e-05 24.3 20.7 0.18 12.0 0.1 5.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EKG19241.1 - 0.022 15.0 0.0 0.022 15.0 0.0 9.5 10 1 0 10 10 10 0 C2H2-type zinc finger DEAD PF00270.24 EKG19243.1 - 3.8e-45 153.3 0.0 1.7e-43 148.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG19243.1 - 2.5e-23 81.7 0.0 7.4e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EKG19243.1 - 0.00026 19.8 0.0 0.00045 19.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EKG19243.1 - 0.0025 17.6 0.0 0.0075 16.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EKG19243.1 - 0.15 10.4 0.0 0.47 8.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) BOP1NT PF08145.7 EKG19244.1 - 1.2e-104 349.6 6.4 1.2e-104 349.6 4.4 1.9 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 EKG19244.1 - 6.6e-31 105.0 3.8 1.4e-11 43.7 0.4 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat NPCBM_assoc PF10633.4 EKG19244.1 - 0.076 13.0 0.5 15 5.7 0.0 3.3 4 0 0 4 4 4 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Sigma70_ner PF04546.8 EKG19244.1 - 1.1 8.7 14.0 2.7 7.5 9.7 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 EKG19244.1 - 2.3 6.6 17.0 3.4 6.0 11.8 1.1 1 0 0 1 1 1 0 Daxx Family PTRF_SDPR PF15237.1 EKG19244.1 - 3.2 7.0 7.1 5.6 6.2 4.9 1.3 1 0 0 1 1 1 0 PTRF/SDPR family HLH PF00010.21 EKG19245.1 - 2.3e-14 52.8 0.2 5.8e-14 51.5 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MARVEL PF01284.18 EKG19246.1 - 6.8e-23 81.0 23.4 8.4e-23 80.7 16.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF485 PF04341.7 EKG19246.1 - 0.0083 15.8 4.4 0.0083 15.8 3.0 2.8 1 1 1 2 2 2 1 Protein of unknown function, DUF485 PalH PF08733.5 EKG19246.1 - 5.8 5.6 10.5 0.81 8.4 4.3 1.6 1 1 1 2 2 2 0 PalH/RIM21 BTB PF00651.26 EKG19247.1 - 2.1e-13 50.2 0.0 1.1e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DUF3533 PF12051.3 EKG19248.1 - 5e-95 318.4 12.6 5.9e-95 318.2 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) XRCC4 PF06632.7 EKG19250.1 - 0.0001 21.2 12.8 0.00025 20.0 8.8 1.7 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 GMC_oxred_N PF00732.14 EKG19252.1 - 3.8e-13 49.2 0.0 4.5e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG19252.1 - 6.4e-07 28.5 0.3 7.6e-07 28.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG19252.1 - 6.6e-05 21.9 0.2 0.0001 21.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG19252.1 - 0.00016 21.6 0.1 0.00061 19.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG19252.1 - 0.00039 20.3 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG19252.1 - 0.00079 18.4 0.1 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EKG19252.1 - 0.0037 15.9 0.2 0.0051 15.4 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.9 EKG19252.1 - 0.004 15.6 0.2 0.0054 15.2 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EKG19252.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG19252.1 - 0.037 14.1 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG19252.1 - 0.047 12.7 0.2 0.068 12.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EKG19252.1 - 0.081 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Ank PF00023.25 EKG19253.1 - 2.9e-13 48.9 0.1 5.5e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EKG19253.1 - 2.5e-12 46.9 0.0 4.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 EKG19253.1 - 7.5e-11 41.8 0.9 7.5e-11 41.8 0.6 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.1 EKG19253.1 - 1.2e-10 41.2 0.2 1.2e-09 38.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG19253.1 - 9.1e-08 32.4 0.1 3.6e-07 30.5 0.0 2.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG19253.1 - 1.9e-07 30.6 0.0 0.0003 20.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Metal_resist PF13801.1 EKG19254.1 - 0.33 10.9 5.6 0.25 11.3 0.7 2.4 2 0 0 2 2 2 0 Heavy-metal resistance ABM PF03992.11 EKG19255.1 - 1.3e-06 28.3 0.2 1.7e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF482 PF04339.7 EKG19255.1 - 0.0027 16.6 0.1 0.0031 16.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF482 Metallophos PF00149.23 EKG19256.1 - 3e-40 137.7 0.0 5.2e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EKG19256.1 - 1.1e-31 108.6 0.8 3.4e-31 107.1 0.6 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EKG19256.1 - 7.7e-21 73.5 5.0 6.1e-16 57.8 0.4 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EKG19256.1 - 7.7e-13 47.4 4.7 0.00046 19.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKG19256.1 - 1e-08 34.4 4.3 0.026 14.4 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKG19256.1 - 3.6e-05 23.6 4.3 0.0011 19.0 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG19256.1 - 0.00013 22.5 0.1 0.03 15.0 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKG19256.1 - 0.012 15.4 0.2 0.24 11.2 0.0 2.6 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EKG19256.1 - 0.019 14.8 0.0 0.19 11.5 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG19256.1 - 0.02 15.3 0.1 4.8 7.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt4 PF06093.8 EKG19257.1 - 4.5e-32 109.7 0.1 5.5e-32 109.4 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger RNA_POL_M_15KD PF02150.11 EKG19257.1 - 0.032 13.9 0.8 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Asp PF00026.18 EKG19258.1 - 1.5e-73 247.8 6.6 1.9e-73 247.4 4.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKG19258.1 - 1.2e-08 35.1 2.1 2.7e-08 33.9 0.5 2.3 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EKG19258.1 - 7.1e-05 22.4 0.0 0.0021 17.6 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EKG19258.1 - 0.013 15.9 1.6 9.9 6.7 0.2 3.4 2 1 0 2 2 2 0 Aspartyl protease DUF1675 PF07897.6 EKG19258.1 - 0.022 14.6 0.1 0.038 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Rep_fac_C PF08542.6 EKG19259.1 - 9.5e-20 70.3 0.0 1.9e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EKG19259.1 - 8.8e-13 48.2 0.0 8.2e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EKG19259.1 - 1.3e-11 44.8 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EKG19259.1 - 3.7e-07 30.0 0.0 8.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG19259.1 - 6.6e-06 26.2 0.0 0.00015 21.8 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 EKG19259.1 - 1e-05 25.2 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EKG19259.1 - 1.2e-05 24.1 0.0 0.031 12.9 0.0 2.9 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EKG19259.1 - 1.6e-05 25.0 0.1 0.021 14.9 0.0 2.8 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.7 EKG19259.1 - 2.5e-05 23.4 0.0 7e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 EKG19259.1 - 9.5e-05 22.0 0.0 0.00023 20.7 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EKG19259.1 - 0.00033 20.0 0.1 0.1 12.0 0.0 2.4 1 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EKG19259.1 - 0.00051 19.6 0.0 0.00083 18.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 EKG19259.1 - 0.00098 18.6 0.0 0.09 12.1 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EKG19259.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EKG19259.1 - 0.0031 16.7 0.0 0.028 13.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EKG19259.1 - 0.0043 16.7 0.2 0.035 13.8 0.1 2.4 1 1 0 2 2 2 1 NTPase AAA_11 PF13086.1 EKG19259.1 - 0.0059 16.2 0.0 0.0085 15.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EKG19259.1 - 0.0068 15.2 0.0 0.014 14.2 0.0 1.5 1 0 0 1 1 1 1 ArgK protein DEAD PF00270.24 EKG19259.1 - 0.008 15.6 0.1 0.3 10.5 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.1 EKG19259.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EKG19259.1 - 0.02 14.8 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EKG19259.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 EKG19259.1 - 0.035 13.5 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EKG19259.1 - 0.078 13.1 0.1 0.54 10.4 0.0 2.2 1 1 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EKG19259.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 EKG19259.1 - 0.14 11.8 0.1 0.42 10.3 0.0 1.9 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) Cys_Met_Meta_PP PF01053.15 EKG19260.1 - 3.2e-56 190.2 0.0 3.6e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ank_3 PF13606.1 EKG19261.1 - 0.00015 21.6 0.1 0.92 9.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EKG19261.1 - 0.0015 18.8 0.1 0.0073 16.6 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG19261.1 - 0.026 15.0 0.5 0.29 11.6 0.1 2.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG19261.1 - 0.041 14.1 0.1 4.8 7.5 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AMP-binding PF00501.23 EKG19262.1 - 2.6e-82 276.4 0.0 3.2e-82 276.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mid1 PF12929.2 EKG19263.1 - 1.1e-41 142.9 0.0 1.4e-41 142.6 0.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Acetyltransf_1 PF00583.19 EKG19264.1 - 1.3e-07 31.5 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EKG19264.1 - 5.1e-07 29.7 0.0 1.9e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EKG19264.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG19264.1 - 0.0047 16.7 0.0 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG19264.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 EKG19264.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 EKG19264.1 - 0.16 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.1 EKG19265.1 - 2.9e-09 37.1 0.0 3.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG19265.1 - 3.5e-08 33.0 0.0 5.3e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family APS_kinase PF01583.15 EKG19266.1 - 1.3e-67 226.3 0.0 1.6e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EKG19266.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG19266.1 - 1.8e-05 25.5 0.1 2.7e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG19266.1 - 0.00027 21.2 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EKG19266.1 - 0.00056 19.2 0.0 0.00088 18.5 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EKG19266.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain 6PF2K PF01591.13 EKG19266.1 - 0.13 11.2 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Fungal_trans PF04082.13 EKG19267.1 - 4.6e-21 74.8 0.0 7.9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG19267.1 - 0.015 15.1 7.9 0.026 14.4 5.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Retinal PF15449.1 EKG19267.1 - 0.038 11.6 9.7 0.07 10.7 6.7 1.4 1 0 0 1 1 1 0 Retinal protein AAA_2 PF07724.9 EKG19268.1 - 3.2e-47 160.6 0.0 9.5e-45 152.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EKG19268.1 - 3.1e-26 91.0 0.1 2e-25 88.4 0.1 2.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EKG19268.1 - 3.2e-21 75.9 0.0 8.7e-12 45.3 0.0 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG19268.1 - 2.5e-13 49.9 0.1 2.3e-08 33.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKG19268.1 - 2.3e-10 40.7 11.0 0.00066 19.7 0.0 5.2 4 2 2 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 EKG19268.1 - 3.8e-10 40.0 0.5 0.00069 19.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 EKG19268.1 - 5e-09 35.8 0.6 4.4e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 EKG19268.1 - 1e-06 28.6 1.3 0.043 13.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EKG19268.1 - 7.9e-06 25.6 0.0 0.2 11.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain IstB_IS21 PF01695.12 EKG19268.1 - 3.1e-05 23.4 0.4 0.19 11.1 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EKG19268.1 - 3.9e-05 23.4 10.6 0.042 13.5 0.1 4.8 3 2 0 3 3 3 1 Archaeal ATPase MobB PF03205.9 EKG19268.1 - 9.5e-05 22.1 0.0 0.036 13.7 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EKG19268.1 - 0.00013 21.6 0.4 0.35 10.4 0.0 4.0 2 1 1 4 4 3 1 AAA domain AAA_28 PF13521.1 EKG19268.1 - 0.00014 21.8 0.6 0.23 11.4 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EKG19268.1 - 0.0002 21.0 0.0 0.014 15.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EKG19268.1 - 0.00022 22.0 9.7 0.043 14.6 0.1 4.3 3 2 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EKG19268.1 - 0.00027 20.1 0.3 1.5 7.9 0.0 3.7 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EKG19268.1 - 0.0003 21.0 7.6 0.14 12.5 0.1 3.8 4 0 0 4 4 3 2 AAA domain TrwB_AAD_bind PF10412.4 EKG19268.1 - 0.00034 19.3 0.0 0.21 10.1 0.0 2.7 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 EKG19268.1 - 0.00046 19.6 0.0 0.055 12.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EKG19268.1 - 0.0012 18.9 0.0 0.74 10.0 0.0 3.0 2 1 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EKG19268.1 - 0.004 16.2 0.0 0.21 10.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.8 EKG19268.1 - 0.0057 15.6 0.2 0.69 8.7 0.1 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.10 EKG19268.1 - 0.0061 16.4 3.5 1.2 8.9 0.0 3.8 3 2 2 5 5 5 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EKG19268.1 - 0.008 16.0 0.0 4.3 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EKG19268.1 - 0.0083 15.5 0.4 4.5 6.6 0.0 3.3 2 2 1 3 3 3 0 AAA domain DUF258 PF03193.11 EKG19268.1 - 0.0088 15.2 0.0 4.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EKG19268.1 - 0.0092 16.2 1.7 1.5 9.0 0.0 3.2 3 0 0 3 3 3 1 ABC transporter PduV-EutP PF10662.4 EKG19268.1 - 0.011 15.2 0.0 0.68 9.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EKG19268.1 - 0.012 15.0 0.0 3.4 7.0 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UvrD-helicase PF00580.16 EKG19268.1 - 0.012 14.9 4.9 0.16 11.2 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_24 PF13479.1 EKG19268.1 - 0.013 15.0 0.0 0.42 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EKG19268.1 - 0.014 15.8 0.1 0.94 9.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EKG19268.1 - 0.015 14.8 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EKG19268.1 - 0.025 14.2 0.0 7.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EKG19268.1 - 0.073 12.4 2.4 0.39 10.1 0.0 2.8 3 1 0 3 3 2 0 AAA-like domain AAA_29 PF13555.1 EKG19268.1 - 0.13 11.8 0.0 6.5 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.12 EKG19268.1 - 0.15 11.8 4.9 20 4.9 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_15 PF13175.1 EKG19268.1 - 0.17 10.8 4.4 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 EKG19268.1 - 0.24 11.0 3.1 0.67 9.6 0.0 2.9 4 0 0 4 4 2 0 NTPase Atg14 PF10186.4 EKG19268.1 - 1 8.2 9.5 2.2 7.1 6.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EKG19268.1 - 1.4 8.5 15.7 1.2 8.7 9.4 1.9 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 EKG19268.1 - 2 7.9 22.8 0.16 11.5 11.8 2.0 2 0 0 2 2 2 0 IncA protein OmpH PF03938.9 EKG19268.1 - 2.5 7.9 12.0 7.8 6.4 8.3 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dynamin_N PF00350.18 EKG19268.1 - 2.7 7.8 5.7 32 4.3 0.0 2.6 2 1 0 2 2 2 0 Dynamin family V_ATPase_I PF01496.14 EKG19268.1 - 3.8 5.2 6.5 5.4 4.7 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EKG19268.1 - 8.2 5.3 12.8 16 4.4 8.9 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 EF1_GNE PF00736.14 EKG19269.1 - 1.1e-31 108.3 4.8 1.8e-31 107.6 3.4 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EKG19269.1 - 1.6e-15 56.9 5.9 1.6e-15 56.9 4.1 3.3 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EKG19269.1 - 0.0003 21.2 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EKG19269.1 - 0.082 12.9 0.3 0.33 10.9 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF211 PF02680.9 EKG19269.1 - 0.15 11.8 1.8 0.3 10.8 1.3 1.5 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 Sas10 PF09368.5 EKG19271.1 - 1.6e-29 101.9 11.2 1.6e-29 101.9 7.7 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EKG19271.1 - 2.8e-15 56.2 1.6 2e-14 53.5 0.0 3.1 3 0 0 3 3 3 1 Sas10/Utp3/C1D family MutS_V PF00488.16 EKG19272.1 - 2.7e-54 184.0 0.1 4.9e-53 179.9 0.1 2.3 1 1 0 1 1 1 1 MutS domain V adh_short PF00106.20 EKG19272.1 - 1.1e-26 93.6 0.4 1.1e-26 93.6 0.3 2.4 2 0 0 2 2 2 1 short chain dehydrogenase MutS_III PF05192.13 EKG19272.1 - 3.5e-24 85.7 0.0 6.6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 MutS domain III KR PF08659.5 EKG19272.1 - 7.1e-12 45.3 0.6 3.2e-11 43.2 0.4 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG19272.1 - 6.1e-09 35.9 0.2 6.1e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EKG19272.1 - 5.2e-05 22.9 0.1 0.00013 21.6 0.1 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EKG19272.1 - 6.4e-05 23.0 0.3 0.0004 20.4 0.1 2.3 2 0 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EKG19272.1 - 0.00019 20.5 0.0 0.00041 19.4 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 EKG19272.1 - 0.00092 19.5 0.4 0.0031 17.9 0.0 2.1 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent MutS_IV PF05190.13 EKG19272.1 - 0.0011 19.0 0.0 0.0035 17.4 0.0 1.8 2 0 0 2 2 1 1 MutS family domain IV ADH_zinc_N PF00107.21 EKG19272.1 - 0.0044 16.5 0.1 0.099 12.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EKG19272.1 - 0.0067 16.6 0.0 0.021 15.0 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.13 EKG19272.1 - 0.012 15.6 0.0 0.046 13.7 0.0 2.0 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EKG19272.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EKG19272.1 - 0.021 14.8 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_29 PF13555.1 EKG19272.1 - 0.043 13.3 0.1 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Phage_prot_Gp6 PF05133.9 EKG19272.1 - 0.072 11.6 0.2 0.19 10.2 0.1 1.6 2 0 0 2 2 2 0 Phage portal protein, SPP1 Gp6-like MFS_1 PF07690.11 EKG19273.1 - 2.8e-41 141.4 31.3 2.8e-41 141.4 21.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19273.1 - 3.5e-14 52.2 11.2 3.5e-14 52.2 7.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1072 PF06380.6 EKG19273.1 - 0.59 9.8 2.9 0.48 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) CHORD PF04968.7 EKG19274.1 - 2.5e-51 171.7 16.9 1.3e-25 89.3 3.2 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EKG19274.1 - 6.1e-13 49.1 0.0 9e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 EKG19275.1 - 6.5e-14 51.9 0.0 7.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EKG19275.1 - 9.5e-05 22.3 0.1 0.00024 21.0 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin DUF1223 PF06764.6 EKG19275.1 - 0.011 15.5 0.1 0.022 14.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1223) HpcH_HpaI PF03328.9 EKG19276.1 - 1.7e-32 112.0 0.0 2.2e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EKG19276.1 - 0.0078 15.4 0.1 0.7 9.0 0.0 2.6 3 0 0 3 3 3 2 Phosphoenolpyruvate phosphomutase DUF2156 PF09924.4 EKG19276.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) LRR_4 PF12799.2 EKG19280.1 - 2.6e-26 90.7 45.0 1.7e-06 27.5 0.9 9.3 8 2 2 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG19280.1 - 2e-18 65.8 38.5 3.4e-05 23.5 0.5 6.7 5 1 3 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 EKG19280.1 - 1.5e-08 33.4 39.6 10 6.5 0.0 12.5 12 1 1 13 13 13 6 Leucine Rich Repeat LRR_9 PF14580.1 EKG19280.1 - 1.9e-07 30.8 9.2 0.0018 17.8 0.2 4.5 2 1 2 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 EKG19280.1 - 7.1e-06 25.4 33.5 4.6 7.8 0.2 12.2 12 0 0 12 12 12 2 Leucine rich repeat LRR_6 PF13516.1 EKG19280.1 - 0.0023 17.8 33.3 7.2 7.0 0.1 10.6 11 2 2 13 13 13 4 Leucine Rich repeat PG_binding_2 PF08823.6 EKG19283.1 - 8.5e-05 22.5 6.5 0.52 10.4 0.2 4.0 1 1 4 5 5 5 3 Putative peptidoglycan binding domain TPR_12 PF13424.1 EKG19283.1 - 0.0026 17.6 7.3 1.8 8.5 0.5 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat Cytochrom_B562 PF07361.6 EKG19283.1 - 0.0038 17.5 6.7 0.93 9.9 0.3 3.2 1 1 3 4 4 4 3 Cytochrome b562 EAP30 PF04157.11 EKG19283.1 - 0.0086 15.2 4.6 0.24 10.5 0.8 2.4 1 1 1 2 2 2 2 EAP30/Vps36 family DUF4177 PF13783.1 EKG19283.1 - 0.017 14.7 3.3 26 4.5 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4177) DUF1631 PF07793.6 EKG19283.1 - 0.046 11.8 14.3 0.072 11.2 9.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) Orthopox_F14 PF06076.7 EKG19283.1 - 0.089 12.8 0.2 21 5.2 0.0 3.2 1 1 3 4 4 4 0 Orthopoxvirus F14 protein Pex19 PF04614.7 EKG19283.1 - 0.1 12.2 9.4 0.27 10.8 0.9 2.1 1 1 1 2 2 2 0 Pex19 protein family Trehalose_PPase PF02358.11 EKG19283.1 - 0.12 11.2 1.6 15 4.4 0.0 3.6 2 2 2 4 4 4 0 Trehalose-phosphatase CAML PF14963.1 EKG19283.1 - 0.17 11.1 3.4 0.19 11.0 2.4 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DSBA PF01323.15 EKG19283.1 - 0.44 10.0 5.0 0.74 9.3 0.3 2.7 1 1 2 3 3 3 0 DSBA-like thioredoxin domain CHAD PF05235.9 EKG19283.1 - 0.87 9.1 12.3 0.83 9.1 7.6 1.6 1 1 1 2 2 2 0 CHAD domain DUF3708 PF12501.3 EKG19283.1 - 1 9.1 8.3 1.4 8.7 1.0 2.3 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter DUF2894 PF11445.3 EKG19283.1 - 1.6 8.9 17.8 5 7.3 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) Secretin_N PF03958.12 EKG19283.1 - 4.9 7.4 10.8 7e+03 -2.7 7.5 4.3 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain DUF3275 PF11679.3 EKG19283.1 - 8.7 5.9 12.9 1.3 8.5 3.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3275) SH3_9 PF14604.1 EKG19284.1 - 2.7e-07 30.0 0.5 6.9e-07 28.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain DUF2668 PF10873.3 EKG19284.1 - 0.00028 21.0 0.6 0.00028 21.0 0.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2668) SH3_1 PF00018.23 EKG19284.1 - 0.00047 19.4 0.4 0.00081 18.7 0.3 1.4 1 0 0 1 1 1 1 SH3 domain Mid2 PF04478.7 EKG19284.1 - 0.0018 17.6 0.1 0.0049 16.2 0.0 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor PPR_2 PF13041.1 EKG19286.1 - 8.3e-44 147.3 4.5 1.5e-09 37.6 0.0 13.9 10 3 6 16 16 16 8 PPR repeat family PPR_3 PF13812.1 EKG19286.1 - 3.4e-26 89.2 21.4 0.00012 22.0 0.0 16.0 18 0 0 18 18 18 4 Pentatricopeptide repeat domain PPR PF01535.15 EKG19286.1 - 1.4e-25 87.4 15.2 0.00024 20.8 0.0 13.4 13 0 0 13 13 13 5 PPR repeat PPR_1 PF12854.2 EKG19286.1 - 2.7e-20 71.5 0.0 1.7e-07 30.5 0.0 9.3 10 0 0 10 10 10 2 PPR repeat RPM2 PF08579.6 EKG19286.1 - 0.00015 21.8 0.0 0.022 14.8 0.0 3.8 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.1 EKG19286.1 - 0.0011 18.5 2.3 4.1 7.4 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF1542 PF07564.6 EKG19286.1 - 0.65 10.0 8.2 0.51 10.3 0.4 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) GHMP_kinases_N PF00288.21 EKG19287.1 - 4e-14 52.4 1.3 1.1e-13 51.0 0.9 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EKG19287.1 - 3.8e-09 36.6 0.0 9.4e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 GHMP kinases C terminal HALZ PF02183.13 EKG19287.1 - 1.2 8.9 3.1 5.2 6.8 0.5 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper Rad60-SLD_2 PF13881.1 EKG19288.1 - 1.4e-13 50.7 0.0 2e-13 50.1 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EKG19288.1 - 1.3e-05 24.4 0.0 2.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EKG19288.1 - 0.00081 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 EKG19289.1 - 1.4e-21 76.7 0.0 2e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 MAPEG PF01124.13 EKG19290.1 - 1.9e-16 59.8 1.3 2.2e-16 59.6 0.9 1.1 1 0 0 1 1 1 1 MAPEG family Rab5ip PF07019.7 EKG19290.1 - 0.03 14.4 0.2 0.11 12.6 0.3 1.8 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) tRNA_int_end_N2 PF12928.2 EKG19291.1 - 1.3e-17 62.9 0.0 2.5e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EKG19291.1 - 0.0026 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain MFS_1 PF07690.11 EKG19292.1 - 3.2e-07 29.4 23.4 4e-07 29.0 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EKG19292.1 - 0.095 12.1 8.3 0.27 10.7 0.9 2.3 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 adh_short PF00106.20 EKG19293.1 - 4.6e-21 75.4 0.7 6e-21 75.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19293.1 - 5.9e-12 45.6 0.0 8.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG19293.1 - 2.6e-06 27.3 0.0 4.9e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG19293.1 - 7.8e-06 25.4 0.2 1.3e-05 24.7 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG19293.1 - 3.7e-05 22.7 0.1 0.00017 20.6 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EKG19293.1 - 0.00078 19.4 0.5 0.0054 16.7 0.4 1.9 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EKG19293.1 - 0.0069 15.3 0.0 0.0094 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Nsp1 PF11501.3 EKG19293.1 - 0.072 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Non structural protein Nsp1 Arginase PF00491.16 EKG19294.1 - 1.1e-82 277.4 0.7 1.3e-82 277.2 0.5 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EKG19294.1 - 0.002 18.3 0.2 0.0041 17.3 0.1 1.4 1 0 0 1 1 1 1 UPF0489 domain Glyoxalase_4 PF13669.1 EKG19295.1 - 1.3e-16 60.5 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Aconitase PF00330.15 EKG19296.1 - 1.3e-143 478.8 0.0 1.6e-143 478.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EKG19296.1 - 2.8e-33 114.8 0.0 5.5e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ADH_zinc_N PF00107.21 EKG19297.1 - 3.1e-19 68.8 0.2 4.5e-19 68.2 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EKG19297.1 - 0.00076 19.0 0.0 0.0017 17.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.1 EKG19297.1 - 0.0027 18.5 0.3 0.0066 17.3 0.2 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG19297.1 - 0.0046 16.1 0.0 0.01 15.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 EKG19297.1 - 0.06 13.8 0.0 0.32 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EKG19297.1 - 0.08 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 EKG19297.1 - 0.086 12.8 0.0 0.28 11.2 0.0 2.0 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain OCD_Mu_crystall PF02423.10 EKG19297.1 - 0.11 11.2 0.2 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family zf-C2H2_2 PF12756.2 EKG19298.1 - 2.4e-24 85.3 4.6 1.5e-23 82.8 0.0 2.7 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EKG19298.1 - 0.17 11.6 2.2 0.13 11.9 0.2 1.7 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Aldolase_II PF00596.16 EKG19300.1 - 1.5e-46 158.3 0.8 1.9e-46 157.9 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Glycos_transf_1 PF00534.15 EKG19300.1 - 0.07 12.5 0.1 0.17 11.3 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 AAA PF00004.24 EKG19303.1 - 6.5e-19 68.4 0.0 1.5e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG19303.1 - 0.00033 20.3 0.0 0.00067 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EKG19303.1 - 0.0032 16.5 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKG19303.1 - 0.0041 17.9 0.0 0.014 16.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EKG19303.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EKG19303.1 - 0.0061 16.7 0.2 0.051 13.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG19303.1 - 0.012 15.6 0.4 0.041 13.8 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EKG19303.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EKG19303.1 - 0.037 13.7 0.1 0.1 12.3 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EKG19303.1 - 0.097 11.8 0.1 0.24 10.5 0.1 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zot PF05707.7 EKG19303.1 - 0.11 11.9 0.1 2.4 7.5 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_24 PF13479.1 EKG19303.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 EKG19304.1 - 5.1e-15 55.7 0.4 1e-14 54.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG19304.1 - 6.8e-09 35.6 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 KR domain PspC PF04024.7 EKG19304.1 - 1.5 8.3 3.8 0.61 9.5 0.6 1.9 2 0 0 2 2 2 0 PspC domain Pro_isomerase PF00160.16 EKG19305.1 - 1.4e-50 171.4 0.0 1.7e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CBM_15 PF03426.9 EKG19305.1 - 0.061 12.7 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF3659 PF12396.3 EKG19305.1 - 0.11 12.1 1.1 0.19 11.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Arrestin_C PF02752.17 EKG19306.1 - 4.7e-15 55.8 0.0 5.8e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain zf-TRAF PF02176.13 EKG19306.1 - 0.12 12.7 0.3 0.31 11.4 0.0 1.7 2 0 0 2 2 2 0 TRAF-type zinc finger BRCT PF00533.21 EKG19308.1 - 2e-07 31.0 0.0 9e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKG19308.1 - 0.0055 16.5 1.5 0.051 13.4 0.1 2.3 2 0 0 2 2 2 1 twin BRCT domain DUF2419 PF10343.4 EKG19310.1 - 1.3e-138 461.1 0.0 1.6e-138 460.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 EKG19310.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) zf-UBP PF02148.14 EKG19310.1 - 0.14 12.3 1.0 0.34 11.0 0.2 1.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GCFC PF07842.7 EKG19311.1 - 0.099 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein NARP1 PF12569.3 EKG19312.1 - 1.9e-188 627.4 13.8 1.9e-188 627.4 9.5 2.5 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EKG19312.1 - 4.1e-17 61.1 23.4 0.00068 20.0 0.1 11.0 9 3 4 13 13 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EKG19312.1 - 1.5e-16 59.8 16.7 2.9e-05 23.6 0.2 7.5 6 2 1 7 7 7 4 TPR repeat TPR_19 PF14559.1 EKG19312.1 - 3.6e-16 59.2 24.0 0.0023 18.2 2.0 8.8 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKG19312.1 - 1.2e-12 46.7 27.0 0.00032 20.3 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 EKG19312.1 - 1.2e-11 44.9 28.0 0.0025 18.4 0.4 8.1 7 3 2 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EKG19312.1 - 3.1e-11 42.3 22.4 1.9e-05 24.0 0.2 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EKG19312.1 - 1.2e-08 34.7 19.8 0.019 14.8 0.2 7.7 4 1 4 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG19312.1 - 2.3e-08 34.0 12.7 0.3 11.2 0.2 6.4 5 1 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EKG19312.1 - 1.7e-06 27.7 12.0 0.0054 16.5 0.4 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EKG19312.1 - 4.7e-06 26.3 5.2 5.1 7.5 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EKG19312.1 - 7.6e-05 21.9 15.3 0.019 14.0 1.3 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKG19312.1 - 0.00026 20.5 18.2 0.0096 15.6 0.1 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat BTAD PF03704.12 EKG19312.1 - 0.01 16.1 7.3 0.038 14.3 0.6 3.4 3 0 0 3 3 2 0 Bacterial transcriptional activator domain Coatomer_E PF04733.9 EKG19312.1 - 0.041 13.0 0.9 2.9 7.0 0.0 3.4 3 1 0 4 4 4 0 Coatomer epsilon subunit TPR_6 PF13174.1 EKG19312.1 - 0.042 14.3 23.5 2.6 8.7 0.1 9.1 10 0 0 10 10 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKG19312.1 - 0.048 13.5 3.1 1.3 9.0 0.2 3.8 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EKG19312.1 - 0.19 11.5 0.1 0.19 11.5 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Seryl_tRNA_N PF02403.17 EKG19312.1 - 3.9 7.5 9.7 2.8 7.9 0.4 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_4 PF07721.9 EKG19312.1 - 5.7 7.6 9.7 4.2 8.0 0.5 4.6 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EKG19312.1 - 7.5 6.6 14.0 1.9e+02 2.1 0.0 6.3 6 1 1 7 7 6 0 Tetratricopeptide repeat MIT PF04212.13 EKG19312.1 - 7.5 6.5 17.3 0.51 10.2 0.2 5.3 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain CS PF04969.11 EKG19313.1 - 1.3e-10 41.6 0.1 1.9e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 CS domain Snf7 PF03357.16 EKG19314.1 - 8.5e-23 80.5 13.5 8.5e-23 80.5 9.4 1.3 1 1 0 1 1 1 1 Snf7 DUF1704 PF08014.6 EKG19314.1 - 0.053 12.5 2.2 0.078 11.9 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Rogdi_lz PF10259.4 EKG19314.1 - 0.13 11.3 3.8 0.19 10.7 1.6 2.0 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein MbeB_N PF04837.7 EKG19314.1 - 0.13 12.4 3.0 2.8 8.0 0.2 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region YlqD PF11068.3 EKG19314.1 - 0.14 12.2 13.8 0.018 15.0 5.6 2.2 2 0 0 2 2 2 0 YlqD protein DUF1284 PF06935.6 EKG19314.1 - 0.27 11.4 1.2 0.5 10.5 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Atg14 PF10186.4 EKG19314.1 - 0.67 8.8 14.6 0.053 12.4 6.7 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 AKNA PF12443.3 EKG19314.1 - 2.7 8.0 9.7 0.27 11.2 1.6 2.6 2 2 0 2 2 2 0 AT-hook-containing transcription factor Arginase PF00491.16 EKG19315.1 - 2.9e-44 151.4 0.0 3.3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fapy_DNA_glyco PF01149.19 EKG19317.1 - 5.7e-27 94.3 0.0 1e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EKG19317.1 - 1.4e-21 76.0 0.0 2.2e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain PAS PF00989.19 EKG19317.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 PAS fold SIR2 PF02146.12 EKG19318.1 - 3.6e-57 192.9 0.0 4.8e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EKG19318.1 - 8.8e-05 22.1 0.0 0.0003 20.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EKG19318.1 - 0.0059 16.3 0.6 2.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain zinc_ribbon_2 PF13240.1 EKG19318.1 - 0.5 9.9 2.4 0.94 9.0 1.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain DUF4414 PF14377.1 EKG19319.1 - 0.039 13.8 0.0 3.5 7.5 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4414) Macoilin PF09726.4 EKG19319.1 - 8 4.6 10.5 7.9 4.6 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Aldo_ket_red PF00248.16 EKG19321.1 - 1.1e-56 191.7 0.0 1.3e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Shadoo PF14999.1 EKG19322.1 - 0.59 9.9 3.9 0.88 9.4 2.7 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Nexin_C PF08628.7 EKG19323.1 - 4.2e-28 97.7 0.8 9e-28 96.6 0.0 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EKG19323.1 - 1.2e-20 73.3 0.6 3.2e-20 72.0 0.1 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.14 EKG19323.1 - 6.1e-12 45.6 0.2 2.8e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain GCV_T PF01571.16 EKG19324.1 - 1.1e-58 198.0 0.0 1.5e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EKG19324.1 - 2.8e-24 84.9 0.5 4.9e-24 84.1 0.4 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain V-ATPase_C PF03223.10 EKG19325.1 - 1.4e-122 409.1 0.5 1.6e-122 409.0 0.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Tht1 PF04163.7 EKG19325.1 - 0.06 11.7 0.2 0.12 10.7 0.1 1.3 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein MRG PF05712.8 EKG19325.1 - 0.11 11.3 1.1 1.9 7.3 0.1 2.8 3 0 0 3 3 3 0 MRG Rox3 PF08633.5 EKG19326.1 - 1.3e-29 103.8 4.3 1.3e-29 103.8 3.0 2.0 2 1 0 2 2 2 1 Rox3 mediator complex subunit DUF1908 PF08926.6 EKG19326.1 - 3.8 6.2 5.9 1.9 7.1 2.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) Rad10 PF03834.9 EKG19327.1 - 7.4e-32 108.8 0.0 1.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EKG19327.1 - 0.00089 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain 14-3-3 PF00244.15 EKG19329.1 - 9.6e-07 28.1 0.0 1.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF3131 PF11329.3 EKG19329.1 - 0.17 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) MFS_1 PF07690.11 EKG19330.1 - 2.8e-30 105.2 26.1 2.8e-30 105.2 18.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily WBP-1 PF11669.3 EKG19330.1 - 0.25 11.4 2.4 3.6 7.7 0.3 2.7 2 0 0 2 2 2 0 WW domain-binding protein 1 Nop52 PF05997.7 EKG19331.1 - 9.5e-65 218.0 0.2 1.2e-64 217.6 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Methyltransf_4 PF02390.12 EKG19332.1 - 7.7e-45 152.3 0.0 8.6e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Vac_ImportDeg PF09783.4 EKG19333.1 - 1.8e-69 232.7 1.8 2.3e-69 232.4 1.2 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 EKG19334.1 - 3.5e-77 256.9 0.3 4.1e-77 256.7 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 EKG19335.1 - 8.9e-94 314.6 6.6 1.4e-93 314.0 4.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EKG19335.1 - 3.6e-62 207.8 0.0 1.2e-61 206.1 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EKG19335.1 - 5e-62 207.7 1.3 1.2e-61 206.4 0.9 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EKG19335.1 - 9.5e-12 45.0 6.4 2.3e-06 27.7 0.0 4.5 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 EKG19335.1 - 0.00012 21.8 0.2 0.057 13.5 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 EKG19335.1 - 0.00085 19.2 10.0 0.019 14.8 0.0 3.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EKG19335.1 - 0.0011 19.3 6.8 0.013 15.9 0.0 4.6 4 2 2 6 6 6 2 HEAT-like repeat AP4E_app_platf PF14807.1 EKG19335.1 - 0.027 14.6 0.4 0.15 12.3 0.1 2.5 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform RE_Alw26IDE PF09665.5 EKG19335.1 - 0.23 10.1 5.2 1 7.9 0.2 2.9 3 1 1 4 4 4 0 Type II restriction endonuclease (RE_Alw26IDE) DAGK_cat PF00781.19 EKG19336.1 - 1.6e-22 79.3 0.1 2.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ribosomal_L23 PF00276.15 EKG19337.1 - 2.2e-12 46.7 0.0 4.7e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 Toxin_32 PF08120.6 EKG19340.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.4 3 0 0 3 3 3 0 Tamulustoxin family RNase_PH PF01138.16 EKG19341.1 - 5.9e-11 42.8 0.0 1.2e-10 41.7 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 MFS_1 PF07690.11 EKG19342.1 - 3.7e-15 55.5 33.7 1.4e-13 50.3 5.2 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EKG19342.1 - 7.4e-10 38.4 0.7 7.4e-10 38.4 0.5 2.0 2 0 0 2 2 2 1 Nodulin-like MFS_1_like PF12832.2 EKG19342.1 - 0.082 12.7 4.0 0.51 10.1 0.5 3.1 2 0 0 2 2 2 0 MFS_1 like family FixP_N PF14715.1 EKG19342.1 - 0.13 11.6 2.9 12 5.3 0.3 3.2 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF1180 PF06679.7 EKG19342.1 - 0.15 11.9 0.2 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) RecX PF02631.11 EKG19342.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 RecX family Lipase_GDSL PF00657.17 EKG19344.1 - 7.3e-09 35.7 0.0 1.3e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKG19344.1 - 7.5e-08 32.7 0.0 1.1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HMG_box PF00505.14 EKG19345.1 - 4.1e-15 55.8 7.1 1.7e-11 44.1 0.6 3.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EKG19345.1 - 2e-11 44.0 14.6 2.2e-09 37.5 1.4 3.4 3 0 0 3 3 3 2 HMG-box domain DUF4065 PF13274.1 EKG19345.1 - 0.66 10.7 3.3 4.5 8.0 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4065) Mucin PF01456.12 EKG19345.1 - 2.4 7.9 18.7 4.4 7.0 13.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MSA-2c PF12238.3 EKG19345.1 - 4.3 6.9 12.1 19 4.8 6.0 2.6 2 1 1 3 3 3 0 Merozoite surface antigen 2c HC2 PF07382.6 EKG19345.1 - 5.1 6.9 42.6 0.89 9.3 26.2 1.8 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 PH_6 PF15406.1 EKG19346.1 - 2.2e-36 124.3 3.5 2.2e-36 124.3 2.4 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain MF_alpha_N PF05436.6 EKG19346.1 - 1.3 8.7 0.0 1.3 8.7 0.0 3.3 3 0 0 3 3 3 0 Mating factor alpha precursor N-terminus Sulfate_transp PF00916.15 EKG19348.1 - 2.9e-27 95.3 0.9 4.3e-27 94.8 0.6 1.2 1 0 0 1 1 1 1 Sulfate transporter family YfhO PF09586.5 EKG19348.1 - 0.074 11.0 1.9 0.11 10.4 1.3 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF373 PF04123.8 EKG19348.1 - 0.14 11.1 5.6 0.18 10.8 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Rab5ip PF07019.7 EKG19348.1 - 0.74 9.9 9.3 0.76 9.9 0.0 3.4 2 1 2 4 4 4 0 Rab5-interacting protein (Rab5ip) Sld5 PF05916.6 EKG19349.1 - 1.3e-12 47.9 0.0 2.2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 EKG19349.1 - 0.063 12.8 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) TMF_TATA_bd PF12325.3 EKG19351.1 - 4.6e-40 136.1 14.6 4.6e-40 136.1 10.1 6.4 3 2 3 6 6 6 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EKG19351.1 - 5.2e-20 71.0 11.0 5.2e-20 71.0 7.6 9.0 5 4 1 7 7 7 4 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 EKG19351.1 - 0.0061 16.5 16.7 0.0061 16.5 11.6 6.4 3 2 2 5 5 5 1 Domain of unknown function (DUF4200) AAA_13 PF13166.1 EKG19351.1 - 0.0072 14.8 63.3 0.092 11.1 15.9 3.2 2 1 1 3 3 3 3 AAA domain CorA PF01544.13 EKG19351.1 - 0.019 13.9 0.3 0.019 13.9 0.2 4.7 4 1 0 4 4 4 0 CorA-like Mg2+ transporter protein WD40_alt PF14077.1 EKG19351.1 - 1.4 8.6 18.7 2 8.0 0.5 5.2 5 0 0 5 5 5 0 Alternative WD40 repeat motif NPV_P10 PF05531.7 EKG19351.1 - 2.8 8.2 28.3 1.6 9.0 1.1 7.0 3 3 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Ank_5 PF13857.1 EKG19352.1 - 3.3e-41 138.3 20.6 1.7e-10 40.7 0.3 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG19352.1 - 3.1e-39 133.1 8.1 5e-19 68.4 0.9 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG19352.1 - 5.8e-39 131.8 15.1 2.5e-08 34.2 0.4 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EKG19352.1 - 1.1e-32 110.2 8.0 2.3e-05 23.9 0.3 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_3 PF13606.1 EKG19352.1 - 1.8e-29 98.8 2.3 0.0023 18.0 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat DUF4301 PF14134.1 EKG19352.1 - 0.13 10.8 0.0 2.7 6.4 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4301) Amidohydro_2 PF04909.9 EKG19353.1 - 1.2e-46 159.5 1.2 4.4e-46 157.6 0.1 2.2 2 1 1 3 3 3 1 Amidohydrolase zf-C2H2_4 PF13894.1 EKG19353.1 - 0.01 16.0 2.0 0.035 14.4 1.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG19353.1 - 0.12 12.7 1.2 0.3 11.5 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type AT_hook PF02178.14 EKG19353.1 - 0.27 11.0 3.1 0.71 9.7 2.1 1.7 1 0 0 1 1 1 0 AT hook motif Macoilin PF09726.4 EKG19354.1 - 3.2 5.9 4.8 3.2 5.9 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Period_C PF12114.3 EKG19354.1 - 5.8 6.4 8.7 6.9 6.2 6.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region BNIP3 PF06553.7 EKG19354.1 - 8.7 5.6 11.9 35 3.6 8.3 1.8 1 1 0 1 1 1 0 BNIP3 Skp1_POZ PF03931.10 EKG19355.1 - 7.6e-13 48.3 0.0 9.8e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short_C2 PF13561.1 EKG19356.1 - 0.00011 22.1 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ThiF PF00899.16 EKG19357.1 - 1.4e-42 144.7 0.1 2.6e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EKG19357.1 - 5.3e-30 102.7 0.1 4.8e-29 99.7 0.2 2.2 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EKG19357.1 - 2.3e-21 74.8 1.8 2.3e-21 74.8 1.2 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EKG19357.1 - 7.1e-20 70.9 0.3 1.9e-19 69.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EKG19357.1 - 0.0005 20.2 0.2 0.0053 16.9 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EKG19357.1 - 0.00077 19.5 0.0 0.0022 18.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_7 PF03492.10 EKG19357.1 - 0.044 12.5 0.3 0.092 11.4 0.0 1.6 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase La PF05383.12 EKG19358.1 - 1.7e-18 66.1 0.1 2.8e-18 65.4 0.1 1.3 1 0 0 1 1 1 1 La domain COesterase PF00135.23 EKG19359.1 - 7.6e-56 189.9 0.0 8.7e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG19359.1 - 2.5e-08 33.7 0.0 3.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG19359.1 - 0.0024 17.6 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family SET PF00856.23 EKG19360.1 - 6.2e-25 88.3 1.0 2.3e-24 86.5 0.2 2.3 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 EKG19360.1 - 1.6e-14 54.0 3.9 1.8e-14 53.8 1.1 2.2 2 1 0 2 2 2 1 Pre-SET motif AGT PF11440.3 EKG19361.1 - 0.054 12.3 0.1 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Cupin_8 PF13621.1 EKG19362.1 - 2.6e-18 66.4 0.0 3.5e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EKG19362.1 - 0.0042 16.3 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.6 EKG19362.1 - 0.013 15.0 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.17 EKG19362.1 - 0.094 12.9 0.0 0.4 10.9 0.0 2.0 1 1 0 1 1 1 0 JmjC domain, hydroxylase Prefoldin PF02996.12 EKG19363.1 - 6.4e-24 83.9 0.5 1.4e-22 79.5 0.4 2.0 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EKG19363.1 - 0.0011 18.7 0.6 0.45 10.3 0.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit EMP24_GP25L PF01105.19 EKG19363.1 - 0.005 16.5 0.1 0.53 9.9 0.0 2.1 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.5 EKG19363.1 - 0.0059 16.7 0.2 0.54 10.3 0.0 2.1 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family Sec2p PF06428.6 EKG19363.1 - 0.013 15.2 1.4 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CENP-Q PF13094.1 EKG19363.1 - 0.047 13.7 1.2 1.6 8.7 0.1 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Uds1 PF15456.1 EKG19363.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Up-regulated During Septation Tektin PF03148.9 EKG19363.1 - 0.1 11.1 0.3 0.91 7.9 0.0 1.9 2 0 0 2 2 2 0 Tektin family DUF4515 PF14988.1 EKG19363.1 - 0.14 11.8 1.3 2.4 7.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Baculo_PEP_C PF04513.7 EKG19363.1 - 0.28 10.9 4.4 0.8 9.5 0.5 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fungal_trans PF04082.13 EKG19364.1 - 4.6e-22 78.1 0.0 7.4e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG19365.1 - 5.3e-35 120.7 24.8 6.4e-35 120.4 17.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF605 PF04652.11 EKG19366.1 - 9.4 5.5 9.5 10 5.3 6.6 1.0 1 0 0 1 1 1 0 Vta1 like CFEM PF05730.6 EKG19367.1 - 3.5e-15 55.5 10.6 4.4e-15 55.2 7.3 1.1 1 0 0 1 1 1 1 CFEM domain DDHD PF02862.12 EKG19369.1 - 1.1e-40 139.8 0.2 6e-23 81.8 0.0 2.7 2 1 1 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.2 EKG19369.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Nop53 PF07767.6 EKG19369.1 - 0.031 13.2 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) bZIP_1 PF00170.16 EKG19370.1 - 1.3e-05 25.0 8.2 2.1e-05 24.3 5.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG19370.1 - 0.001 18.8 7.7 0.0017 18.1 5.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EKG19370.1 - 0.012 15.8 5.7 0.021 15.1 3.9 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor AAA PF00004.24 EKG19371.1 - 2e-14 53.9 0.0 4e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG19371.1 - 3.6e-11 43.3 1.9 1.7e-10 41.1 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain BAH PF01426.13 EKG19371.1 - 9e-11 41.5 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 EKG19371.1 - 5.2e-09 36.3 0.0 1.7e-07 31.4 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EKG19371.1 - 0.00024 21.9 0.0 0.0021 18.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EKG19371.1 - 0.00045 19.9 0.1 0.0021 17.7 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EKG19371.1 - 0.0065 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_11 PF13086.1 EKG19371.1 - 0.0068 16.0 0.6 0.01 15.4 0.0 1.7 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EKG19371.1 - 0.013 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EKG19371.1 - 0.016 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EKG19371.1 - 0.019 14.9 0.0 0.056 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EKG19371.1 - 0.023 13.3 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKG19371.1 - 0.026 14.2 0.0 0.39 10.3 0.0 2.5 1 1 0 1 1 1 0 Archaeal ATPase Zot PF05707.7 EKG19371.1 - 0.034 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) RNA_helicase PF00910.17 EKG19371.1 - 0.11 12.7 0.0 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase PIF1 PF05970.9 EKG19371.1 - 0.11 11.4 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase WD40 PF00400.27 EKG19372.1 - 8.6e-55 180.7 12.7 1.3e-09 37.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EKG19372.1 - 8.9e-05 20.8 5.3 1.3 7.1 0.1 4.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EKG19372.1 - 0.0014 18.1 0.3 1.7 8.0 0.0 2.5 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EKG19372.1 - 0.025 13.3 0.0 9.6 4.8 0.0 3.2 2 1 1 3 3 3 0 Nup133 N terminal like NACHT PF05729.7 EKG19373.1 - 1.1e-09 38.2 0.1 3.9e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EKG19373.1 - 0.0013 18.8 0.1 0.028 14.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain XH PF03469.9 EKG19373.1 - 0.0019 17.8 0.5 0.017 14.7 0.1 2.6 2 0 0 2 2 2 1 XH domain AAA_18 PF13238.1 EKG19373.1 - 0.0045 17.2 1.1 0.014 15.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG19373.1 - 0.0053 17.5 0.2 0.041 14.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EKG19373.1 - 0.023 14.9 0.4 0.19 12.0 0.0 2.8 3 1 0 3 3 3 0 ABC transporter AAA_10 PF12846.2 EKG19373.1 - 0.046 13.1 1.9 0.12 11.7 0.0 2.6 4 0 0 4 4 4 0 AAA-like domain AAA_16 PF13191.1 EKG19373.1 - 0.078 12.9 0.0 0.078 12.9 0.0 3.5 4 1 0 4 4 4 0 AAA ATPase domain RNA_helicase PF00910.17 EKG19373.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF4452 PF14618.1 EKG19374.1 - 1.5e-62 210.2 13.0 1.9e-62 209.9 9.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Effector_1 PF04518.7 EKG19375.1 - 0.032 13.2 0.4 0.034 13.1 0.2 1.0 1 0 0 1 1 1 0 Effector from type III secretion system DivIC PF04977.10 EKG19375.1 - 1.6 8.2 4.3 0.73 9.3 0.8 1.9 2 0 0 2 2 2 0 Septum formation initiator Het-C PF07217.6 EKG19376.1 - 1e-284 945.4 0.0 1.3e-284 945.1 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SNF5 PF04855.7 EKG19380.1 - 2.3e-82 276.1 0.0 3.1e-82 275.7 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EKG19380.1 - 2.6e-05 23.4 1.4 6.4e-05 22.2 0.9 1.7 1 0 0 1 1 1 1 GATA zinc finger TFIIA_gamma_N PF02268.11 EKG19381.1 - 8.1e-09 34.9 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EKG19381.1 - 6.7e-08 32.2 1.5 9.8e-08 31.6 1.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Pinin_SDK_memA PF04696.8 EKG19382.1 - 0.53 9.8 16.0 0.24 10.9 9.4 1.7 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SURF4 PF02077.10 EKG19383.1 - 4e-96 321.4 4.5 4.5e-96 321.3 3.1 1.0 1 0 0 1 1 1 1 SURF4 family IU_nuc_hydro PF01156.14 EKG19384.1 - 2e-47 161.9 0.1 5.1e-40 137.6 0.0 2.2 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Bclt PF15318.1 EKG19384.1 - 0.084 12.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis Clathrin PF00637.15 EKG19387.1 - 9.3e-21 73.9 4.5 1.2e-19 70.3 0.9 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EKG19387.1 - 3.3e-20 71.6 0.0 8.3e-20 70.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.1 EKG19387.1 - 0.00077 19.8 4.2 1.5 9.6 0.0 3.9 3 1 0 3 3 2 2 Tetratricopeptide repeat zf-RING_2 PF13639.1 EKG19387.1 - 0.00082 19.1 4.9 0.0016 18.2 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EKG19387.1 - 0.0024 17.5 4.2 0.005 16.5 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 EKG19387.1 - 0.0025 17.4 1.5 0.0073 15.9 0.0 2.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EKG19387.1 - 0.008 16.0 3.1 0.022 14.6 0.1 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 EKG19387.1 - 0.01 15.8 4.2 0.02 14.9 2.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EKG19387.1 - 0.012 15.4 0.7 0.026 14.3 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EKG19387.1 - 0.023 14.7 2.1 0.049 13.7 1.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_8 PF13181.1 EKG19387.1 - 0.024 14.4 0.3 0.024 14.4 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EKG19387.1 - 0.032 14.5 6.6 1.7 9.0 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.5 EKG19387.1 - 0.06 12.4 0.0 7.1 5.6 0.0 2.5 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like zf-C3HC4 PF00097.20 EKG19387.1 - 0.11 12.1 4.2 0.23 11.1 2.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0564 PF10595.4 EKG19387.1 - 0.13 11.1 0.2 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Apc3 PF12895.2 EKG19387.1 - 0.19 11.8 9.0 2.7 8.2 0.1 3.8 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 PHD PF00628.24 EKG19387.1 - 0.73 9.5 3.9 1.5 8.5 2.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EKG19387.1 - 0.84 9.5 4.4 1.7 8.6 3.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TPR_12 PF13424.1 EKG19387.1 - 1 9.3 8.7 0.15 11.9 0.4 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKG19387.1 - 4 7.2 6.2 2 8.1 0.4 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 EKG19388.1 - 4.9e-14 51.7 0.0 8.3e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG19388.1 - 2.1e-12 46.8 0.0 3.6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EKG19388.1 - 2.6e-06 27.7 3.0 2.6e-06 27.7 2.1 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EKG19388.1 - 0.00039 20.2 0.0 0.00066 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2712 PF10916.3 EKG19388.1 - 0.076 12.9 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2712) Ribosomal_S25 PF03297.10 EKG19388.1 - 0.089 12.8 2.1 0.23 11.5 1.5 1.7 1 0 0 1 1 1 0 S25 ribosomal protein Aldedh PF00171.17 EKG19389.1 - 6.3e-186 618.2 0.3 7.1e-186 618.0 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EKG19389.1 - 0.038 12.7 0.1 0.081 11.6 0.0 1.4 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EKG19389.1 - 0.071 12.3 0.0 4 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) HAD_2 PF13419.1 EKG19390.1 - 1.3e-10 41.8 0.6 1.7e-10 41.4 0.4 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.7 EKG19390.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Acid_PPase PF12689.2 EKG19390.1 - 0.041 13.5 0.1 0.085 12.4 0.0 1.6 2 0 0 2 2 2 0 Acid Phosphatase Globin PF00042.17 EKG19390.1 - 0.14 12.4 1.6 1.1 9.6 0.2 2.3 1 1 0 2 2 2 0 Globin SIP PF04954.8 EKG19390.1 - 0.87 9.9 5.5 0.64 10.4 0.3 2.2 2 0 0 2 2 2 0 Siderophore-interacting protein adh_short_C2 PF13561.1 EKG19391.1 - 9.5e-27 94.2 0.1 1.1e-26 94.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG19391.1 - 2.1e-26 92.8 0.2 2.8e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19391.1 - 5.8e-10 39.1 0.1 1.4e-09 37.9 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG19391.1 - 3e-05 23.5 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Homeobox PF00046.24 EKG19392.1 - 4.5e-14 51.8 0.7 8.9e-14 50.8 0.5 1.5 1 0 0 1 1 1 1 Homeobox domain HAD_2 PF13419.1 EKG19393.1 - 5.4e-14 52.7 0.0 1.3e-13 51.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG19393.1 - 7.8e-10 39.5 0.2 1e-07 32.6 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG19393.1 - 3e-06 26.8 0.1 5.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EKG19393.1 - 2.6e-05 24.4 0.0 3.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGA_cap PF09587.5 EKG19393.1 - 0.021 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Hydrolase_6 PF13344.1 EKG19393.1 - 0.041 13.7 0.0 6.9 6.6 0.0 2.8 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EKG19394.1 - 2.1e-25 88.4 20.6 5e-25 87.2 14.3 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EKG19394.1 - 5.4e-22 77.9 0.1 3.3e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG19394.1 - 7.6e-07 28.5 0.2 4.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EKG19394.1 - 8.2e-06 25.3 0.0 0.014 14.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EKG19394.1 - 0.001 18.9 5.6 0.27 11.0 0.1 3.7 2 2 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EKG19394.1 - 0.0013 17.9 0.1 0.0023 17.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EKG19394.1 - 0.0027 18.1 0.2 1.4 9.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 EKG19394.1 - 0.01 15.3 0.1 0.069 12.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EKG19394.1 - 0.029 14.3 3.8 0.11 12.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain ArgK PF03308.11 EKG19394.1 - 0.11 11.2 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EKG19394.1 - 0.28 11.5 0.0 0.28 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain Aldedh PF00171.17 EKG19396.1 - 3.1e-103 345.5 0.0 3.9e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 EKG19397.1 - 5.9e-34 117.3 0.0 2.4e-23 82.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19397.1 - 9.8e-19 67.4 0.0 6.1e-13 48.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKG19397.1 - 0.31 9.7 0.0 0.49 9.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase adh_short PF00106.20 EKG19399.1 - 1.3e-15 57.7 0.1 1.9e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG19399.1 - 6.4e-09 35.9 0.0 8.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG19399.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1416 PF07210.7 EKG19399.1 - 0.15 11.7 1.4 5.8 6.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1416) Vps26 PF03643.10 EKG19403.1 - 4.8e-129 428.9 0.7 5.8e-129 428.7 0.5 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EKG19403.1 - 0.00022 21.0 0.2 0.79 9.5 0.0 3.4 2 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EKG19403.1 - 0.014 15.4 0.1 0.054 13.5 0.1 2.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF432 PF04254.8 EKG19403.1 - 0.038 13.9 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) SKI PF01202.17 EKG19404.1 - 2.9e-12 46.7 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EKG19404.1 - 3e-11 43.3 0.0 4.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG19404.1 - 4.3e-11 43.6 0.0 5.5e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG19404.1 - 2e-10 41.0 0.0 3.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EKG19404.1 - 1.6e-05 24.8 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG19404.1 - 1.7e-05 24.9 0.0 2.9e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EKG19404.1 - 7e-05 21.7 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EKG19404.1 - 0.00054 19.8 0.0 0.0015 18.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EKG19404.1 - 0.00059 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA PF00004.24 EKG19404.1 - 0.00091 19.4 0.0 0.0016 18.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EKG19404.1 - 0.00096 19.4 0.0 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter CoaE PF01121.15 EKG19404.1 - 0.0013 18.2 0.0 0.0035 16.7 0.0 1.7 2 0 0 2 2 2 1 Dephospho-CoA kinase NACHT PF05729.7 EKG19404.1 - 0.0013 18.3 0.0 0.0029 17.3 0.0 1.5 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 EKG19404.1 - 0.0015 18.2 0.1 0.028 14.1 0.0 2.2 1 1 1 2 2 2 1 NTPase Cytidylate_kin2 PF13189.1 EKG19404.1 - 0.0018 18.2 0.0 0.006 16.5 0.0 2.0 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_16 PF13191.1 EKG19404.1 - 0.0022 17.9 0.0 0.0044 17.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EKG19404.1 - 0.0025 17.4 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_19 PF13245.1 EKG19404.1 - 0.0066 16.1 0.1 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EKG19404.1 - 0.0067 15.5 0.0 0.011 14.8 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin MutS_V PF00488.16 EKG19404.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 MutS domain V AAA_5 PF07728.9 EKG19404.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EKG19404.1 - 0.023 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EKG19404.1 - 0.025 13.7 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EKG19404.1 - 0.028 14.0 0.1 0.048 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 EKG19404.1 - 0.038 13.5 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 EKG19404.1 - 0.054 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EKG19404.1 - 0.057 13.1 0.0 0.099 12.3 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 EKG19404.1 - 0.067 12.3 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 dNK PF01712.14 EKG19404.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_29 PF13555.1 EKG19404.1 - 0.081 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EKG19404.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.18 EKG19405.1 - 2.3e-73 246.3 0.0 4e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EKG19405.1 - 1.8e-18 65.9 0.1 3.9e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EKG19405.1 - 2.3e-13 49.5 0.0 5.1e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EKG19405.1 - 0.082 12.5 0.3 6.9 6.4 0.1 2.7 1 1 1 2 2 2 0 Biotin-lipoyl like p450 PF00067.17 EKG19406.1 - 1.1e-70 238.5 0.0 1.2e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EKG19407.1 - 1e-73 248.4 0.0 1.3e-73 248.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EKG19407.1 - 3.3e-41 140.6 0.0 5e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EKG19407.1 - 9.1e-05 22.7 0.0 0.00069 19.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG19407.1 - 0.0014 18.6 0.0 0.004 17.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG19407.1 - 0.0039 17.1 0.0 0.035 13.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG19407.1 - 0.0044 15.9 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EKG19407.1 - 0.0064 15.4 0.0 0.083 11.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG19407.1 - 0.0066 14.9 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.11 EKG19407.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 EKG19407.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain GDI PF00996.13 EKG19407.1 - 0.21 9.8 0.0 0.4 8.9 0.0 1.4 1 0 0 1 1 1 0 GDP dissociation inhibitor Ank_5 PF13857.1 EKG19408.1 - 3.1e-12 46.2 0.7 1.5e-08 34.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG19408.1 - 8.7e-08 32.4 0.1 2.3e-05 24.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG19408.1 - 4.8e-07 30.0 1.1 0.00037 20.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKG19408.1 - 0.00013 21.5 4.1 0.01 15.5 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EKG19408.1 - 0.00077 19.4 0.2 0.014 15.5 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat Acyl-CoA_dh_2 PF08028.6 EKG19408.1 - 3.9 7.7 7.7 0.53 10.5 2.0 1.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain PAP2 PF01569.16 EKG19409.1 - 8.9e-25 86.8 1.5 8.9e-25 86.8 1.1 2.2 2 2 0 2 2 2 1 PAP2 superfamily CsbD PF05532.7 EKG19410.1 - 6.5e-10 38.5 4.0 0.00032 20.3 0.4 2.1 2 0 0 2 2 2 2 CsbD-like SIR2 PF02146.12 EKG19412.1 - 7.7e-13 48.5 0.0 4.1e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.3 EKG19413.1 - 6.7e-88 295.5 0.0 1.1e-74 251.8 0.0 2.0 1 1 1 2 2 2 2 Mediator complex subunit 16 Apc4_WD40 PF12894.2 EKG19413.1 - 0.11 11.9 0.1 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PI-PLC-X PF00388.14 EKG19414.1 - 2e-13 49.9 0.0 3.1e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Kelch_6 PF13964.1 EKG19415.1 - 4.7e-06 26.5 0.9 0.0041 17.2 0.1 4.3 4 0 0 4 4 4 1 Kelch motif Rifin_STEVOR PF02009.11 EKG19415.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Kelch_3 PF13415.1 EKG19415.1 - 0.013 15.6 0.1 0.013 15.6 0.1 4.9 7 0 0 7 7 7 0 Galactose oxidase, central domain Kelch_5 PF13854.1 EKG19415.1 - 0.031 14.2 5.4 0.18 11.8 0.0 3.6 3 0 0 3 3 3 0 Kelch motif TMEM154 PF15102.1 EKG19415.1 - 0.05 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Kelch_1 PF01344.20 EKG19415.1 - 0.069 12.7 4.8 0.34 10.4 0.1 3.1 3 0 0 3 3 3 0 Kelch motif MatE PF01554.13 EKG19415.1 - 3.5 7.2 7.5 37 3.8 4.2 2.1 2 0 0 2 2 2 0 MatE DUF1180 PF06679.7 EKG19415.1 - 6.4 6.6 7.8 0.4 10.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) CorA PF01544.13 EKG19416.1 - 3.6e-06 26.2 2.2 0.026 13.5 0.3 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Ribosomal_L1 PF00687.16 EKG19417.1 - 1.7e-51 174.6 0.9 2.4e-51 174.2 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Acetyltransf_1 PF00583.19 EKG19417.1 - 8.4e-11 41.7 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG19417.1 - 6.5e-05 23.0 0.2 0.0011 19.1 0.1 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG19417.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG19417.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EKG19417.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MFS_1 PF07690.11 EKG19418.1 - 6.3e-31 107.3 47.0 1e-30 106.6 32.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily SHR3_chaperone PF08229.6 EKG19418.1 - 7.4 5.4 11.8 0.095 11.6 0.5 2.7 2 1 1 3 3 3 0 ER membrane protein SH3 ILVD_EDD PF00920.16 EKG19419.1 - 1.9e-133 445.6 0.2 2.3e-133 445.4 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family TPR_14 PF13428.1 EKG19420.1 - 0.0061 17.0 1.6 0.45 11.2 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat FYVE PF01363.16 EKG19420.1 - 0.046 13.6 5.9 0.16 11.9 4.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger Lipoprotein_15 PF03640.10 EKG19420.1 - 0.25 10.7 3.9 5.8 6.4 0.2 2.6 2 0 0 2 2 2 0 Secreted repeat of unknown function TPR_6 PF13174.1 EKG19420.1 - 0.39 11.2 0.0 0.39 11.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-CCCH PF00642.19 EKG19421.1 - 5.7e-06 25.8 2.9 5.7e-06 25.8 2.0 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ost4 PF10215.4 EKG19422.1 - 6.3e-17 60.7 2.2 7.9e-17 60.4 1.6 1.1 1 0 0 1 1 1 1 Oligosaccaryltransferase DUF772 PF05598.6 EKG19424.1 - 0.068 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Transposase domain (DUF772) DUF605 PF04652.11 EKG19424.1 - 4.5 6.5 36.2 7.4 5.8 25.1 1.4 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EKG19424.1 - 8.5 4.4 42.3 11 4.0 29.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 EKG19424.1 - 9.3 4.1 13.6 12 3.7 9.4 1.2 1 0 0 1 1 1 0 CDC45-like protein KOW PF00467.24 EKG19425.1 - 7.7e-09 34.9 0.8 2.1e-08 33.5 0.5 1.7 1 0 0 1 1 1 1 KOW motif ESCRT-II PF05871.7 EKG19426.1 - 7.6e-53 178.1 0.0 1e-52 177.7 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit IPK PF03770.11 EKG19430.1 - 6.2e-59 198.9 0.0 1.1e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Popeye PF04831.8 EKG19430.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Popeye protein conserved region RIC1 PF07064.8 EKG19431.1 - 1.7e-91 306.2 0.2 2.7e-91 305.5 0.2 1.3 1 0 0 1 1 1 1 RIC1 Inhibitor_I78 PF11720.3 EKG19433.1 - 1.3e-13 50.4 0.0 1.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EKG19433.1 - 0.00016 21.7 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Halo_GVPC PF05465.8 EKG19436.1 - 0.07 13.0 1.1 0.87 9.5 0.1 2.3 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat CPL PF08144.6 EKG19437.1 - 9.2e-20 70.9 0.9 2.1e-18 66.5 0.0 3.4 3 1 1 4 4 4 1 CPL (NUC119) domain UBA PF00627.26 EKG19437.1 - 0.016 14.9 0.1 0.05 13.4 0.1 1.9 1 0 0 1 1 1 0 UBA/TS-N domain RRM_1 PF00076.17 EKG19440.1 - 2e-16 59.3 0.3 1.5e-06 27.7 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG19440.1 - 7.5e-13 48.2 0.6 1.5e-07 31.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG19440.1 - 4.2e-10 39.3 0.0 2.2e-06 27.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EKG19440.1 - 0.063 13.1 0.2 0.063 13.1 0.1 3.4 4 1 0 4 4 4 0 RNA binding motif Ammonium_transp PF00909.16 EKG19441.1 - 3e-121 404.6 30.0 3.4e-121 404.4 20.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.20 EKG19442.1 - 2e-69 233.6 0.0 3.4e-69 232.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19442.1 - 8.6e-38 129.8 0.0 1.5e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG19442.1 - 4.8e-07 29.0 0.0 1.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG19442.1 - 0.00061 19.5 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EKG19442.1 - 0.0034 16.2 0.0 0.0064 15.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Arginosuc_synth PF00764.14 EKG19443.1 - 1.7e-153 511.2 0.0 2e-153 511.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EKG19443.1 - 8e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EKG19443.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EKG19443.1 - 0.014 13.9 0.0 0.021 13.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase UNC45-central PF11701.3 EKG19444.1 - 1.3e-36 125.6 5.9 1.2e-35 122.5 0.4 3.9 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EKG19444.1 - 0.0036 16.6 3.0 0.056 12.8 0.3 2.8 2 0 0 2 2 2 1 CLASP N terminal Atx10homo_assoc PF09759.4 EKG19444.1 - 0.0064 16.2 0.4 0.85 9.3 0.0 3.5 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.15 EKG19444.1 - 0.0091 14.3 6.3 2 6.6 0.2 3.5 2 1 1 3 3 3 3 Adaptin N terminal region Arm PF00514.18 EKG19444.1 - 0.056 13.2 19.1 1.9 8.4 0.1 7.2 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat Polysacc_deac_1 PF01522.16 EKG19445.1 - 1.5e-28 98.8 0.0 2.7e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EKG19445.1 - 1.1e-17 63.7 105.6 2.3e-05 24.2 15.2 5.2 4 1 1 5 5 5 4 Chitin recognition protein AT_hook PF02178.14 EKG19446.1 - 0.018 14.6 17.9 0.15 11.8 3.6 3.2 2 0 0 2 2 2 0 AT hook motif GDPD PF03009.12 EKG19447.1 - 1e-74 251.3 0.0 2e-74 250.3 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EKG19447.1 - 1e-34 118.6 0.1 1.1e-13 51.2 0.1 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG19447.1 - 3.7e-30 102.1 3.3 9.7e-07 28.2 0.0 7.8 8 0 0 8 8 8 5 Ankyrin repeat SPX PF03105.14 EKG19447.1 - 1e-29 104.1 1.4 3e-16 60.0 0.3 3.9 2 1 1 3 3 3 2 SPX domain Ank_4 PF13637.1 EKG19447.1 - 3.8e-29 100.5 0.4 1.7e-10 41.1 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG19447.1 - 1.8e-22 78.8 1.8 7.6e-09 35.5 0.0 7.4 5 1 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG19447.1 - 5.8e-19 66.2 1.2 0.00026 20.9 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Metallophos PF00149.23 EKG19448.1 - 2.8e-07 30.1 2.6 7.5e-07 28.7 1.8 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SNF2_N PF00176.18 EKG19449.1 - 2.7e-64 216.8 0.0 6.1e-64 215.6 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EKG19449.1 - 4.1e-23 80.8 2.4 1.9e-15 56.2 0.5 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EKG19449.1 - 5.9e-16 58.0 0.1 1.7e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 EKG19450.1 - 8.2e-36 123.3 0.0 6.8e-17 62.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKG19450.1 - 7.8e-15 55.6 6.1 0.0099 15.8 0.0 4.4 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EKG19450.1 - 4.8e-10 39.0 5.3 0.0036 16.5 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EKG19450.1 - 1.7e-08 33.9 0.1 0.33 9.9 0.0 4.4 3 2 1 4 4 4 2 AAA ATPase domain AAA PF00004.24 EKG19450.1 - 1.3e-06 28.6 0.1 0.0082 16.3 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG19450.1 - 1.3e-06 29.2 0.0 0.057 14.2 0.0 2.8 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EKG19450.1 - 2.1e-06 28.2 0.0 0.022 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EKG19450.1 - 4.6e-06 26.7 0.0 0.006 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EKG19450.1 - 5.9e-06 25.7 0.7 0.014 14.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 EKG19450.1 - 2.2e-05 24.7 0.0 0.18 12.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EKG19450.1 - 5.3e-05 23.1 0.0 0.049 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 EKG19450.1 - 0.0001 22.0 5.6 0.00022 20.9 3.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.22 EKG19450.1 - 0.00012 21.5 3.1 0.00012 21.5 2.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain VirE PF05272.6 EKG19450.1 - 0.00012 21.6 0.0 0.17 11.3 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Rad17 PF03215.10 EKG19450.1 - 0.00013 20.8 0.0 0.044 12.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EKG19450.1 - 0.00015 20.9 0.0 0.39 9.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 UPF0079 PF02367.12 EKG19450.1 - 0.00017 21.1 0.2 0.0062 16.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EKG19450.1 - 0.0002 21.4 0.1 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EKG19450.1 - 0.00022 20.6 0.1 0.49 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EKG19450.1 - 0.00028 20.5 1.5 0.062 13.0 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EKG19450.1 - 0.00093 18.8 0.1 0.98 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EKG19450.1 - 0.0013 18.1 3.3 0.024 14.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EKG19450.1 - 0.0016 18.1 0.4 0.37 10.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) RLI PF04068.10 EKG19450.1 - 0.0018 17.8 0.6 0.0018 17.8 0.4 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Thymidylate_kin PF02223.12 EKG19450.1 - 0.0018 17.6 0.1 2.2 7.6 0.0 2.7 2 1 0 2 2 2 1 Thymidylate kinase NACHT PF05729.7 EKG19450.1 - 0.002 17.8 2.1 0.058 13.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 EKG19450.1 - 0.0025 18.2 0.0 0.69 10.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 EKG19450.1 - 0.0069 16.3 0.1 2 8.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EKG19450.1 - 0.013 15.3 0.8 7.9 6.4 0.0 3.3 2 2 0 2 2 2 0 AAA domain Fer4_10 PF13237.1 EKG19450.1 - 0.013 15.2 1.9 0.013 15.2 1.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain T2SE PF00437.15 EKG19450.1 - 0.018 13.9 0.4 1.2 7.9 0.0 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EKG19450.1 - 0.021 14.3 1.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EKG19450.1 - 0.024 14.5 0.1 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.1 EKG19450.1 - 0.032 14.9 1.8 0.062 14.0 0.1 2.3 2 0 0 2 2 1 0 4Fe-4S double cluster binding domain AAA_19 PF13245.1 EKG19450.1 - 0.048 13.4 0.5 6.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain DUF815 PF05673.8 EKG19450.1 - 0.07 12.0 0.0 9 5.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EKG19450.1 - 0.072 11.9 0.0 4.4 6.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EKG19450.1 - 0.088 11.9 0.9 0.34 9.9 0.0 2.2 2 0 0 2 2 2 0 KaiC KAP_NTPase PF07693.9 EKG19450.1 - 0.099 11.6 0.0 8.5 5.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain AAA_13 PF13166.1 EKG19450.1 - 0.11 10.9 5.3 0.25 9.7 0.0 3.1 2 1 1 3 3 3 0 AAA domain PIF1 PF05970.9 EKG19450.1 - 0.11 11.3 0.1 15 4.4 0.0 3.2 4 0 0 4 4 4 0 PIF1-like helicase Zeta_toxin PF06414.7 EKG19450.1 - 0.12 11.5 0.7 13 4.8 0.0 3.0 3 0 0 3 3 2 0 Zeta toxin Sigma54_activat PF00158.21 EKG19450.1 - 0.12 11.8 0.2 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain Fer4_7 PF12838.2 EKG19450.1 - 0.12 12.7 6.9 0.049 14.0 1.4 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.10 EKG19450.1 - 0.15 11.7 2.2 3 7.5 0.1 2.7 2 0 0 2 2 2 0 NTPase MukB PF04310.7 EKG19450.1 - 0.18 11.1 1.1 24 4.1 0.0 3.1 3 0 0 3 3 3 0 MukB N-terminal IstB_IS21 PF01695.12 EKG19450.1 - 0.19 11.1 0.1 5.6 6.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Fer4_9 PF13187.1 EKG19450.1 - 0.2 11.9 9.2 0.06 13.6 1.8 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EKG19450.1 - 0.21 11.1 2.5 0.47 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EKG19450.1 - 0.23 11.5 6.7 0.36 10.8 1.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 EKG19450.1 - 0.86 9.5 9.2 0.03 14.2 2.0 1.9 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_3 PF12798.2 EKG19450.1 - 4.3 8.1 10.4 0.61 10.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 EKG19450.1 - 4.8 7.6 7.2 0.76 10.1 0.9 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain FF PF01846.14 EKG19451.1 - 5.5e-48 160.6 23.4 2.9e-15 55.9 0.0 6.7 6 0 0 6 6 6 6 FF domain Trs65 PF12735.2 EKG19452.1 - 3.3e-34 118.6 0.0 6.9e-32 110.9 0.0 2.2 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 EKG19453.1 - 7.8e-23 79.8 0.2 2.1e-22 78.5 0.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Ribonuc_P_40 PF08584.6 EKG19454.1 - 1.3e-45 155.6 0.0 1.9e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit UQ_con PF00179.21 EKG19454.1 - 5.3e-35 119.8 0.0 8e-35 119.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG19454.1 - 0.0031 17.2 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B CN_hydrolase PF00795.17 EKG19455.1 - 6.1e-11 42.0 0.1 2.4e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Polysacc_deac_1 PF01522.16 EKG19456.1 - 2.3e-25 88.5 0.0 3e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EKG19456.1 - 0.0076 15.1 0.0 0.0097 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Terminase_1 PF03354.10 EKG19456.1 - 0.093 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase Fungal_trans_2 PF11951.3 EKG19457.1 - 5.1e-05 22.0 1.2 5.1e-05 22.0 0.8 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain Cyclin_N PF00134.18 EKG19458.1 - 7.3e-12 44.9 0.2 3e-11 42.9 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EKG19458.1 - 0.0086 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat HTH_31 PF13560.1 EKG19458.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Mito_carr PF00153.22 EKG19459.1 - 4.5e-66 218.6 7.7 3.8e-23 81.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EKG19459.1 - 2.1e-23 82.2 1.8 4.8e-12 45.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EKG19459.1 - 3.1e-21 73.0 0.9 6.5e-06 25.0 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 EKG19459.1 - 2.8e-16 58.0 4.7 1.8e-05 23.8 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EKG19459.1 - 4.2e-16 57.3 6.4 0.00043 19.9 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 EKG19459.1 - 3.1e-14 52.3 0.9 1.1e-06 28.1 0.1 3.7 1 1 3 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EKG19459.1 - 5.8e-10 39.1 0.0 6.7e-06 26.1 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region zf-TRAF PF02176.13 EKG19460.1 - 3.5e-10 40.1 33.6 5.3e-09 36.3 5.3 4.0 2 1 3 5 5 5 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EKG19460.1 - 2.8e-07 30.4 7.1 2.8e-07 30.4 4.9 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG19460.1 - 6.8e-07 29.0 9.9 6.8e-07 29.0 6.9 3.2 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKG19460.1 - 4.8e-06 26.1 6.3 4.8e-06 26.1 4.4 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG19460.1 - 1.6e-05 24.5 3.1 1.6e-05 24.5 2.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EKG19460.1 - 0.00011 22.0 6.0 0.00011 22.0 4.2 3.5 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EKG19460.1 - 0.00019 21.1 9.8 0.00019 21.1 6.8 3.2 2 1 1 3 3 1 1 zinc-RING finger domain CENP-F_leu_zip PF10473.4 EKG19460.1 - 0.011 15.5 4.3 0.73 9.6 0.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 EKG19460.1 - 0.029 14.3 1.1 6.1 6.8 0.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EKG19460.1 - 0.086 12.6 0.2 0.086 12.6 0.1 2.1 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.13 EKG19460.1 - 0.41 10.3 2.1 12 5.6 0.2 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 EKG19460.1 - 1.9 8.3 7.0 14 5.5 0.1 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding zf-ZPR1 PF03367.8 EKG19461.1 - 6.6e-114 376.4 0.3 4.5e-56 188.4 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain UPF0547 PF10571.4 EKG19461.1 - 0.21 11.3 9.3 2.5 7.8 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 HypA PF01155.14 EKG19461.1 - 0.68 9.6 5.4 10 5.8 0.1 2.7 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EKG19461.1 - 0.75 10.1 4.5 17 5.8 0.6 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 EKG19461.1 - 1.4 8.5 9.0 2.9 7.5 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EKG19461.1 - 6.5 6.4 6.8 12 5.6 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EKG19461.1 - 8.9 6.0 7.5 10 5.9 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Rpr2 PF04032.11 EKG19462.1 - 5.3e-14 51.8 0.9 1.2e-13 50.7 0.1 1.8 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ETS_PEA3_N PF04621.8 EKG19462.1 - 3.1 6.9 7.6 3.9 6.5 5.2 1.1 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain DBR1 PF05011.8 EKG19463.1 - 4.9e-51 172.4 0.0 9.1e-51 171.5 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EKG19463.1 - 0.0016 17.8 1.0 0.0036 16.7 0.7 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-C2H2_4 PF13894.1 EKG19464.1 - 4.1e-05 23.6 58.7 0.13 12.6 1.1 9.7 9 1 1 10 10 10 6 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG19464.1 - 0.0001 22.4 64.9 0.074 13.4 0.6 9.8 9 1 1 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EKG19464.1 - 0.072 13.2 37.1 3 8.0 0.0 6.5 4 2 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EKG19464.1 - 0.19 11.9 0.0 0.19 11.9 0.0 6.1 7 0 0 7 7 7 0 Zinc-finger of C2H2 type EHN PF06441.7 EKG19467.1 - 3.8e-35 120.1 0.5 3.5e-34 117.0 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EKG19467.1 - 8.5e-12 45.4 0.6 1.7e-11 44.4 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG19467.1 - 0.00041 19.9 0.1 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold WD40 PF00400.27 EKG19469.1 - 3.3e-42 140.8 23.4 8.4e-13 47.6 1.1 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EKG19469.1 - 8.5e-07 28.8 16.2 0.048 13.3 2.8 4.3 2 2 2 4 4 4 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EKG19469.1 - 0.0012 16.8 4.4 0.0023 15.8 0.1 2.3 2 0 0 2 2 2 2 IKI3 family RtcB PF01139.12 EKG19470.1 - 7.4e-79 265.6 0.0 2.3e-76 257.5 0.0 3.1 2 1 0 2 2 2 1 tRNA-splicing ligase RtcB p450 PF00067.17 EKG19471.1 - 2.9e-40 138.1 0.0 3.5e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_2 PF07992.9 EKG19473.1 - 1.1e-09 38.4 0.0 2.2e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG19473.1 - 4.4e-06 25.8 0.1 4.2e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EKG19473.1 - 0.00024 21.2 0.1 0.71 9.8 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG19473.1 - 0.00078 19.2 0.5 0.46 10.2 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 EKG19473.1 - 0.0011 17.9 0.3 0.0045 15.9 0.1 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG19473.1 - 0.0026 17.7 0.1 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EKG19473.1 - 0.0031 16.0 0.0 0.0049 15.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EKG19473.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EKG19473.1 - 0.021 13.6 0.3 0.053 12.3 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EKG19473.1 - 0.095 11.5 0.1 0.66 8.7 0.0 2.0 1 1 1 2 2 2 0 Glucose inhibited division protein A bZIP_1 PF00170.16 EKG19476.1 - 2.5e-14 52.9 4.4 4.2e-14 52.2 3.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG19476.1 - 6.2e-06 25.9 9.8 1.1e-05 25.1 6.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.10 EKG19476.1 - 0.11 12.0 3.2 0.18 11.3 2.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Packaging_FI PF14000.1 EKG19476.1 - 0.13 12.4 2.8 0.3 11.2 2.0 1.6 1 0 0 1 1 1 0 DNA packaging protein FI TPR_10 PF13374.1 EKG19476.1 - 0.15 12.0 1.8 0.26 11.2 1.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF607 PF04678.8 EKG19476.1 - 0.29 11.0 1.9 0.2 11.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF607 M PF02370.11 EKG19476.1 - 0.52 10.8 4.0 1.1 9.8 2.8 1.6 1 0 0 1 1 1 0 M protein repeat bZIP_Maf PF03131.12 EKG19476.1 - 1.2 9.4 8.6 0.49 10.7 4.3 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor Mem_trans PF03547.13 EKG19477.1 - 7.6e-29 100.1 0.0 1.1e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein Ferritin_2 PF13668.1 EKG19478.1 - 3e-23 82.2 0.3 3e-23 82.2 0.2 1.5 2 0 0 2 2 2 1 Ferritin-like domain RNB PF00773.14 EKG19479.1 - 1.7e-88 297.0 0.7 4.3e-88 295.7 0.0 2.0 2 0 0 2 2 2 1 RNB domain GLE1 PF07817.8 EKG19480.1 - 4.5e-28 97.8 0.1 1.3e-27 96.3 0.0 1.8 2 0 0 2 2 2 1 GLE1-like protein DUF1675 PF07897.6 EKG19480.1 - 4.2 7.1 19.8 6.2 6.5 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MarC PF01914.12 EKG19481.1 - 0.64 9.1 4.6 0.23 10.5 1.3 1.6 2 0 0 2 2 2 0 MarC family integral membrane protein DUF202 PF02656.10 EKG19481.1 - 0.69 10.1 6.8 6.8 6.9 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Peptidase_M20 PF01546.23 EKG19482.1 - 3.2e-27 95.2 0.0 4.6e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EKG19482.1 - 4.7e-07 29.5 0.0 9.5e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EKG19482.1 - 0.0014 18.4 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 CoA_trans PF01144.18 EKG19482.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase DUF1604 PF07713.8 EKG19483.1 - 5.6e-39 131.8 7.7 5.6e-39 131.8 2.4 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EKG19483.1 - 3.3e-07 29.9 1.0 1e-06 28.3 0.3 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EKG19483.1 - 0.0045 16.8 1.5 0.021 14.6 0.1 2.7 2 0 0 2 2 2 1 DExH-box splicing factor binding site Pkinase PF00069.20 EKG19484.1 - 6e-79 264.8 0.0 8.8e-79 264.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19484.1 - 1.3e-42 145.6 0.2 4.5e-42 143.9 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EKG19484.1 - 6.9e-19 67.0 0.2 1.1e-18 66.3 0.1 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EKG19484.1 - 4e-06 26.0 0.1 7.5e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKG19484.1 - 9.6e-06 24.7 0.1 0.00018 20.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Ribos_L4_asso_C PF14374.1 EKG19484.1 - 0.0019 18.0 0.0 0.0055 16.5 0.0 1.8 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain APH PF01636.18 EKG19484.1 - 0.002 17.9 0.7 0.017 14.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKG19484.1 - 0.0043 16.4 0.0 0.01 15.1 0.0 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.6 EKG19484.1 - 0.013 14.7 0.1 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 EKG19484.1 - 0.025 13.9 0.5 0.09 12.1 0.3 1.8 1 1 0 1 1 1 0 RIO1 family Rcd1 PF04078.8 EKG19485.1 - 3.1e-132 439.2 3.1 3.8e-132 438.9 2.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.8 EKG19485.1 - 5.9 6.6 10.6 8.2 6.2 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_ligase_A_M PF01068.16 EKG19486.1 - 2.2e-59 200.2 0.2 8.3e-48 162.4 0.1 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EKG19486.1 - 3.4e-52 176.8 0.0 6.9e-52 175.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EKG19486.1 - 7.9e-28 96.7 0.0 3e-27 94.8 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Cid2 PF09774.4 EKG19487.1 - 6.9e-27 94.4 0.0 8.3e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 TMEM151 PF14857.1 EKG19488.1 - 0.0088 14.6 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 1 TMEM151 family PGBA_C PF15437.1 EKG19488.1 - 0.018 15.1 0.9 0.023 14.8 0.6 1.2 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal P_C PF06640.6 EKG19489.1 - 0.032 14.2 1.9 0.061 13.3 1.3 1.4 1 0 0 1 1 1 0 P protein C-terminus FAD_binding_3 PF01494.14 EKG19490.1 - 5.1e-06 25.7 0.0 5.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Exo_endo_phos_2 PF14529.1 EKG19490.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Peroxin-22 PF12827.2 EKG19490.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family AA_permease PF00324.16 EKG19491.1 - 1.1e-111 373.5 34.6 1.2e-111 373.3 24.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG19491.1 - 2.6e-20 72.3 38.6 3.6e-20 71.9 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EKG19491.1 - 1.9 8.2 16.7 0.13 12.0 2.2 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) Myb_Cef PF11831.3 EKG19492.1 - 5.3e-57 192.7 9.4 5.3e-57 192.7 6.5 4.4 5 1 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EKG19492.1 - 1.1e-20 73.3 4.1 1.9e-09 37.4 0.2 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG19492.1 - 2.8e-20 72.1 6.5 1e-13 51.1 1.5 3.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain FoP_duplication PF13865.1 EKG19493.1 - 0.1 13.0 0.9 0.14 12.6 0.6 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Anoctamin PF04547.7 EKG19494.1 - 6.5e-114 381.0 3.7 8.4e-114 380.6 2.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3754 PF12576.3 EKG19494.1 - 0.06 12.9 2.5 0.49 10.0 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) FAD_binding_4 PF01565.18 EKG19495.1 - 7.2e-28 96.8 0.0 1.5e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EKG19495.1 - 2.9e-27 95.5 0.0 4.4e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sulfatase PF00884.18 EKG19497.1 - 5.6e-50 170.2 0.1 7.5e-50 169.8 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EKG19497.1 - 1.1e-06 28.2 0.3 0.034 13.4 0.0 2.9 3 0 0 3 3 3 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EKG19497.1 - 0.0036 15.7 0.1 0.014 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) PHO4 PF01384.15 EKG19498.1 - 9.8e-99 330.0 19.4 1.2e-98 329.8 13.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family CAF-1_p150 PF11600.3 EKG19498.1 - 0.042 13.2 1.3 0.061 12.6 0.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal tRNA_lig_CPD PF08302.6 EKG19499.1 - 1.8e-80 269.9 0.0 2.6e-80 269.3 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EKG19499.1 - 5.8e-79 264.6 0.0 1.1e-78 263.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EKG19499.1 - 8.8e-53 178.6 0.3 2.2e-52 177.2 0.1 1.8 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_17 PF13207.1 EKG19499.1 - 0.0014 19.4 0.0 0.0069 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EKG19499.1 - 0.0022 17.8 0.1 0.0078 16.0 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG19499.1 - 0.026 14.8 0.0 0.1 12.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain GST_C_3 PF14497.1 EKG19500.1 - 3.4e-07 30.6 0.0 6.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG19500.1 - 0.00026 21.1 0.2 0.0045 17.1 0.1 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG19500.1 - 0.051 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG19500.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Aldo_ket_red PF00248.16 EKG19501.1 - 3.3e-53 180.3 0.0 3.9e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Nefa_Nip30_N PF10187.4 EKG19502.1 - 4.7e-23 81.2 8.3 4.7e-23 81.2 5.7 2.3 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.8 EKG19502.1 - 6.1 5.9 19.5 7.9 5.6 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) WD40 PF00400.27 EKG19503.1 - 1.1e-37 126.5 9.3 3.6e-10 39.3 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EKG19503.1 - 9.9e-07 27.3 0.0 2.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 EKG19503.1 - 2.3e-06 27.4 0.1 5.6 6.6 0.0 4.2 2 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EKG19503.1 - 0.002 17.5 0.0 0.64 9.5 0.0 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 EKG19503.1 - 0.006 14.7 0.1 0.07 11.2 0.0 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 AAA_16 PF13191.1 EKG19504.1 - 5.8e-05 23.1 0.0 0.00026 21.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EKG19504.1 - 0.00018 21.2 0.1 0.0008 19.1 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EKG19504.1 - 0.0018 18.4 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG19504.1 - 0.016 14.9 0.1 0.016 14.9 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EKG19504.1 - 0.071 13.9 0.1 0.18 12.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG19504.1 - 0.075 13.3 0.2 0.38 11.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 EKG19504.1 - 0.08 11.7 0.1 0.18 10.5 0.1 1.5 1 0 0 1 1 1 0 ArgK protein HHH_2 PF12826.2 EKG19504.1 - 0.58 10.0 2.3 0.65 9.9 0.1 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif HgmA PF04209.8 EKG19505.1 - 1.7e-188 626.3 0.3 2e-188 626.1 0.2 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 EKG19506.1 - 6.5e-46 156.5 0.0 9.2e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EKG19506.1 - 2.3e-26 91.8 0.0 5.1e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal p450 PF00067.17 EKG19507.1 - 7.5e-65 219.2 0.0 8.6e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sod_Cu PF00080.15 EKG19509.1 - 1.2e-11 44.9 0.1 1.5e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EKG19509.1 - 0.0053 17.3 0.0 0.0074 16.8 0.0 1.3 1 0 0 1 1 1 1 CHRD domain Sugar_tr PF00083.19 EKG19510.1 - 9.4e-19 67.3 13.4 1e-18 67.1 9.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Acetyltransf_7 PF13508.1 EKG19511.1 - 0.00027 21.0 0.0 0.0007 19.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG19511.1 - 0.00088 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG19511.1 - 0.0025 17.9 0.1 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG19511.1 - 0.0041 17.1 0.3 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKG19511.1 - 0.034 13.9 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein IBR PF01485.16 EKG19512.1 - 2e-05 24.3 25.5 0.0005 19.8 4.5 3.9 3 1 0 3 3 3 2 IBR domain HORMA PF02301.13 EKG19513.1 - 1.3e-20 73.8 0.0 3e-20 72.6 0.0 1.5 1 1 0 1 1 1 1 HORMA domain Xpo1 PF08389.7 EKG19514.1 - 1.7e-09 37.7 0.7 0.00093 19.1 0.0 4.7 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 EKG19514.1 - 7.7e-09 35.3 0.2 9.2e-08 31.8 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 EKG19514.1 - 0.0019 16.5 0.0 0.0044 15.3 0.0 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Katanin_con80 PF13925.1 EKG19514.1 - 0.0074 16.0 0.1 4.1 7.1 0.0 3.4 3 0 0 3 3 3 1 con80 domain of Katanin PHB_acc PF05233.8 EKG19514.1 - 0.011 15.4 0.5 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 PHB accumulation regulatory domain V-ATPase_H_N PF03224.9 EKG19514.1 - 0.019 14.0 1.1 0.6 9.1 0.2 2.8 2 0 0 2 2 2 0 V-ATPase subunit H HEAT_2 PF13646.1 EKG19514.1 - 0.099 12.9 5.3 2.4 8.4 0.1 4.7 3 3 0 3 3 3 0 HEAT repeats DUF3808 PF10300.4 EKG19516.1 - 1.7e-128 429.1 0.0 3e-128 428.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EKG19516.1 - 2.5 7.7 11.5 3.8 7.2 2.6 3.5 2 2 0 3 3 3 0 TPR repeat DSS1_SEM1 PF05160.8 EKG19517.1 - 3.4e-23 81.1 17.1 5e-23 80.6 11.9 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 EKG19517.1 - 0.53 9.9 8.1 0.67 9.6 5.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGK PF00162.14 EKG19518.1 - 2.4e-86 289.6 1.7 2.7e-86 289.5 1.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase FIVAR PF07554.8 EKG19518.1 - 0.0014 18.7 1.5 0.14 12.4 0.0 3.2 3 0 0 3 3 3 1 Uncharacterised Sugar-binding Domain PGK PF00162.14 EKG19519.1 - 1.2e-50 172.1 0.0 1.4e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Nup160 PF11715.3 EKG19520.1 - 5.4e-111 371.4 0.0 7.3e-111 370.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 EKG19521.1 - 1.5e-139 463.1 0.0 1.9e-139 462.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EKG19521.1 - 4.7e-14 52.2 0.0 6.5e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EKG19521.1 - 4.1e-08 32.6 0.1 5.4e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EKG19521.1 - 6.7e-08 32.5 0.2 2.2e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EKG19521.1 - 9.3e-07 28.1 0.1 1.7e-06 27.3 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 EKG19521.1 - 0.0043 17.1 0.0 0.021 14.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain PAXNEB PF05625.6 EKG19521.1 - 0.024 13.4 0.1 0.087 11.6 0.0 1.7 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 EKG19521.1 - 0.036 12.9 0.3 0.064 12.1 0.0 1.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF1446 PF07287.6 EKG19522.1 - 7.5e-132 439.1 0.2 9e-132 438.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) DUF883 PF05957.8 EKG19524.1 - 0.29 11.5 0.2 0.29 11.5 0.2 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.20 EKG19526.1 - 3.7e-60 203.2 0.0 5.2e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19526.1 - 6.2e-33 113.9 0.0 1.4e-31 109.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKG19526.1 - 0.0034 16.2 0.0 0.0048 15.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase DUF1387 PF07139.6 EKG19526.1 - 0.38 10.2 0.0 0.38 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1387) DUF2435 PF10363.4 EKG19528.1 - 3.5e-13 49.2 0.4 3e-12 46.2 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EKG19528.1 - 1.8e-09 36.8 0.3 2.7e-08 33.0 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) Adaptin_N PF01602.15 EKG19528.1 - 0.0025 16.2 1.2 0.016 13.5 0.4 2.2 2 0 0 2 2 2 1 Adaptin N terminal region T2SF PF00482.18 EKG19528.1 - 0.0095 15.8 0.5 0.034 14.0 0.4 1.9 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F HEAT_2 PF13646.1 EKG19528.1 - 0.088 13.1 13.8 0.093 13.0 1.6 5.5 5 3 0 5 5 5 0 HEAT repeats BP28CT PF08146.7 EKG19528.1 - 0.18 11.4 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 BP28CT (NUC211) domain Cnd1 PF12717.2 EKG19528.1 - 0.25 11.1 0.3 3.9 7.2 0.0 3.2 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Peptidase_S46 PF10459.4 EKG19528.1 - 0.4 9.0 1.3 0.67 8.3 0.9 1.2 1 0 0 1 1 1 0 Peptidase S46 LSM PF01423.17 EKG19529.1 - 2e-17 62.4 0.0 2.4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EKG19529.1 - 0.023 14.6 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Fe_hyd_lg_C PF02906.9 EKG19530.1 - 2e-60 204.4 0.0 3.8e-60 203.5 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DNA_RNApol_7kD PF03604.8 EKG19531.1 - 6e-15 54.4 5.1 7.6e-15 54.0 3.5 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 EKG19531.1 - 0.0032 17.2 0.2 0.0045 16.7 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EKG19531.1 - 0.027 14.1 0.3 0.032 13.8 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 EKG19531.1 - 0.028 14.1 0.3 0.033 13.9 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF2197 PF09963.4 EKG19531.1 - 0.041 13.8 2.9 1 9.3 0.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) UPF0547 PF10571.4 EKG19531.1 - 0.047 13.4 0.6 0.084 12.5 0.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 A2L_zn_ribbon PF08792.5 EKG19531.1 - 0.057 12.9 2.4 0.56 9.7 2.1 1.9 1 1 1 2 2 2 0 A2L zinc ribbon domain GFA PF04828.9 EKG19531.1 - 0.06 13.2 0.5 2.9 7.9 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF3268 PF11672.3 EKG19531.1 - 0.11 12.5 0.5 0.44 10.6 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3268) DUF2296 PF10058.4 EKG19531.1 - 0.12 12.1 0.2 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Gin PF10764.4 EKG19531.1 - 0.14 11.9 1.0 4.8 6.9 0.0 2.2 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin zf-C4_Topoisom PF01396.14 EKG19531.1 - 0.26 10.8 1.2 5.4 6.6 0.0 2.1 1 1 1 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Pkinase PF00069.20 EKG19532.1 - 1.5e-56 191.4 0.1 4.4e-39 134.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19532.1 - 3.2e-25 88.6 0.3 2.2e-20 72.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EKG19532.1 - 0.00042 20.1 0.8 0.026 14.2 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG19532.1 - 0.00066 18.7 0.0 0.0017 17.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG19532.1 - 0.0022 17.0 0.2 0.0051 15.8 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SpoIIIAH PF12685.2 EKG19532.1 - 0.01 15.3 0.4 0.021 14.3 0.3 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein RIO1 PF01163.17 EKG19532.1 - 0.03 13.6 0.2 0.082 12.2 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.6 EKG19532.1 - 0.061 12.1 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mod_r PF07200.8 EKG19534.1 - 4.6e-11 42.8 1.2 6.5e-11 42.3 0.8 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF3263 PF11662.3 EKG19534.1 - 0.058 12.8 0.1 0.058 12.8 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3263) MFS_1 PF07690.11 EKG19538.1 - 3.5e-21 75.3 31.6 4.2e-21 75.0 21.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG19538.1 - 1.9e-06 26.5 25.1 0.0006 18.3 8.8 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 EKG19538.1 - 0.26 11.3 8.1 0.35 10.9 1.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Tfb4 PF03850.9 EKG19539.1 - 9.6e-110 366.1 0.0 1.1e-109 365.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 EKG19539.1 - 0.00076 19.6 0.2 0.0014 18.7 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C2HC5 PF06221.8 EKG19539.1 - 0.0033 17.1 3.1 0.0057 16.3 2.1 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TerY-C PF15616.1 EKG19539.1 - 0.35 10.7 3.7 0.64 9.9 2.5 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain CTC1 PF15489.1 EKG19539.1 - 0.98 6.6 2.8 1.4 6.1 1.9 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Glyco_hydro_35 PF01301.14 EKG19540.1 - 7.8e-89 298.1 0.0 1e-88 297.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EKG19540.1 - 2.8e-66 222.3 0.7 4.3e-66 221.7 0.5 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EKG19540.1 - 3.2e-46 156.1 5.6 2.2e-24 85.8 0.7 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EKG19540.1 - 3.7e-19 67.8 0.4 1.4e-18 66.0 0.1 2.1 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_2_N PF02837.13 EKG19540.1 - 0.0034 16.9 0.0 0.028 13.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain TPT PF03151.11 EKG19541.1 - 4.9e-21 74.9 10.5 4.9e-21 74.9 7.3 1.9 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EKG19541.1 - 0.00012 21.0 8.3 0.00019 20.4 5.7 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EKG19541.1 - 0.00014 21.9 9.4 0.00014 21.9 6.5 1.9 2 0 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EKG19541.1 - 0.003 16.4 2.7 0.003 16.4 1.9 1.2 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) DUF4051 PF13260.1 EKG19541.1 - 0.06 12.6 0.3 0.11 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) dUTPase PF00692.14 EKG19543.1 - 1.6e-10 40.5 0.0 2.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 dUTPase Ank_2 PF12796.2 EKG19544.1 - 1.2e-20 73.6 1.7 5.8e-10 39.3 0.0 4.1 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EKG19544.1 - 5.3e-12 44.9 3.5 0.00014 21.4 0.0 6.3 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EKG19544.1 - 4.2e-11 42.6 3.5 0.0068 16.6 0.1 4.7 3 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG19544.1 - 5.8e-11 42.5 1.2 0.0012 19.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG19544.1 - 8.1e-07 28.6 4.7 1.1 9.7 0.0 6.5 7 0 0 7 7 7 1 Ankyrin repeat DUF2721 PF11026.3 EKG19544.1 - 0.24 11.0 1.9 0.55 9.8 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Pkinase PF00069.20 EKG19545.1 - 5.8e-70 235.3 0.0 1.2e-69 234.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19545.1 - 1.7e-30 105.9 0.0 2.6e-22 79.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EKG19545.1 - 1.3e-05 24.3 0.1 0.049 12.5 0.0 3.0 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EKG19545.1 - 0.011 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG19545.1 - 0.051 13.2 0.0 1 9.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mre11_DNA_bind PF04152.9 EKG19547.1 - 3.7e-56 189.7 1.0 8.3e-56 188.5 0.1 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EKG19547.1 - 8.3e-28 97.1 5.1 1.2e-27 96.6 3.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG19547.1 - 1.3e-05 25.0 1.3 3.6e-05 23.6 0.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain YL1 PF05764.8 EKG19547.1 - 0.73 9.4 11.6 0.23 11.0 5.7 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Ribosomal_S19 PF00203.16 EKG19548.1 - 1.1e-21 76.2 0.0 1.5e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TRF PF08558.5 EKG19551.1 - 3.9e-50 170.4 0.0 5.3e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EKG19551.1 - 0.00075 19.4 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Actin PF00022.14 EKG19552.1 - 8.6e-91 304.2 0.0 1.9e-90 303.1 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKG19552.1 - 0.0025 16.4 0.0 0.2 10.2 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Asparaginase_2 PF01112.13 EKG19553.1 - 1e-35 122.9 0.8 4.6e-21 74.8 0.0 2.4 2 0 0 2 2 2 2 Asparaginase Ribosomal_S5 PF00333.15 EKG19554.1 - 1.6e-08 34.1 0.3 3.1e-08 33.2 0.1 1.6 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.6 EKG19555.1 - 7e-13 47.9 0.1 1.8e-11 43.3 0.0 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 EKG19555.1 - 5.1e-08 32.6 0.0 8.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 EKG19555.1 - 2.5e-07 30.3 0.0 4.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG19555.1 - 1.1e-05 25.4 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EKG19555.1 - 4.8e-05 23.0 0.0 8.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein TRAM PF01938.15 EKG19555.1 - 9.1e-05 22.1 0.5 0.00024 20.8 0.0 1.9 2 0 0 2 2 2 1 TRAM domain Methyltransf_18 PF12847.2 EKG19555.1 - 0.0001 22.8 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG19555.1 - 0.0004 19.5 1.1 0.00041 19.5 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 EKG19555.1 - 0.0006 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TRM PF02005.11 EKG19555.1 - 0.0015 17.5 0.1 0.0054 15.6 0.0 1.8 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_25 PF13649.1 EKG19555.1 - 0.002 18.4 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG19555.1 - 0.0047 17.3 0.0 0.016 15.6 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltrans_SAM PF10672.4 EKG19555.1 - 0.022 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_12 PF08242.7 EKG19555.1 - 0.051 14.0 0.0 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DNA_pol_B_palm PF14792.1 EKG19556.1 - 2.6e-30 104.7 0.0 4.7e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EKG19556.1 - 3.1e-22 78.0 0.1 6.3e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EKG19556.1 - 6.1e-19 67.3 0.0 1.2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EKG19556.1 - 6.9e-15 54.9 0.1 2.3e-14 53.3 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EKG19556.1 - 0.014 15.7 0.0 0.045 14.0 0.0 1.9 1 0 0 1 1 1 0 Nucleotidyltransferase domain HAD_2 PF13419.1 EKG19557.1 - 1.2e-12 48.4 0.0 5.5e-12 46.2 0.0 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG19557.1 - 4.4e-06 27.2 0.0 3e-05 24.5 0.0 1.8 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG19557.1 - 4.8e-06 26.2 0.0 1.4e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 HAD-hyrolase-like Zn_clus PF00172.13 EKG19558.1 - 0.0077 16.1 7.5 0.013 15.4 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sterol-sensing PF12349.3 EKG19559.1 - 1.1e-36 125.5 6.9 2e-36 124.7 4.8 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EKG19559.1 - 1.1e-12 46.7 2.5 1.6e-12 46.2 1.7 1.1 1 0 0 1 1 1 1 Patched family TPR_12 PF13424.1 EKG19560.1 - 1.5e-11 44.0 0.4 2.2e-05 24.2 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG19560.1 - 3.4e-08 33.9 12.2 0.001 19.6 2.8 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG19560.1 - 1.5e-07 30.9 7.3 0.00047 19.7 0.1 4.0 5 0 0 5 5 5 2 TPR repeat TPR_2 PF07719.12 EKG19560.1 - 1.1e-05 24.9 4.5 0.08 12.8 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKG19560.1 - 2e-05 24.4 0.0 0.24 11.6 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKG19560.1 - 0.00084 19.6 17.1 1.2 9.4 0.0 5.2 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EKG19560.1 - 0.0021 18.5 16.9 2.8 8.8 0.0 5.5 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG19560.1 - 0.0047 16.7 8.6 0.48 10.3 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG19560.1 - 0.0067 16.5 0.0 1.2 9.3 0.0 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EKG19560.1 - 0.012 15.3 0.1 1.3 8.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKG19560.1 - 0.023 14.2 0.3 17 5.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EKG19560.1 - 0.2 11.5 7.1 0.51 10.2 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG19560.1 - 0.2 12.1 3.3 1.9e+02 2.8 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat RWD PF05773.17 EKG19561.1 - 9.5e-23 80.2 0.1 1.7e-22 79.4 0.1 1.4 1 0 0 1 1 1 1 RWD domain Potyvirid-P3 PF13608.1 EKG19561.1 - 0.11 11.5 4.5 0.15 11.1 3.1 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Phage_int_SAM_5 PF13102.1 EKG19561.1 - 0.12 12.3 4.2 0.28 11.1 2.9 1.6 1 1 0 1 1 1 0 Phage integrase SAM-like domain CsgG PF03783.9 EKG19561.1 - 1.5 7.8 5.1 0.19 10.7 0.8 1.5 2 0 0 2 2 2 0 Curli production assembly/transport component CsgG Glyco_hydro_17 PF00332.13 EKG19563.1 - 2.4e-20 72.7 0.2 6.2e-18 64.8 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PGK PF00162.14 EKG19563.1 - 0.014 13.9 0.1 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase MFS_1 PF07690.11 EKG19564.1 - 3.2e-35 121.4 32.9 3.2e-35 121.4 22.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CIA30 PF08547.7 EKG19565.1 - 3.3e-40 137.4 0.0 4.5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RPA_C PF08784.6 EKG19567.1 - 1.2e-18 67.3 0.2 2.8e-18 66.2 0.1 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EKG19567.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HTH_IclR PF09339.5 EKG19567.1 - 0.039 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DEAD PF00270.24 EKG19568.1 - 1.9e-46 157.6 0.1 6.2e-46 155.9 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG19568.1 - 1.2e-22 79.5 0.1 3.1e-22 78.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EKG19568.1 - 2.3e-21 75.3 6.5 7.7e-21 73.6 4.5 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain AP2 PF00847.15 EKG19568.1 - 0.0019 18.3 1.2 0.16 12.1 0.2 3.1 2 0 0 2 2 2 1 AP2 domain Zn_clus PF00172.13 EKG19569.1 - 0.00014 21.7 9.3 0.00022 21.0 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EKG19569.1 - 0.038 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.1 EKG19569.1 - 0.061 13.6 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 PAS domain DnaJ PF00226.26 EKG19570.1 - 5.3e-15 54.9 0.3 1.5e-14 53.4 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.24 EKG19571.1 - 3.2e-42 143.8 0.0 6.3e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EKG19571.1 - 1.5e-25 88.5 0.4 2.9e-25 87.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EKG19571.1 - 4.2e-21 74.5 0.0 1.2e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.19 EKG19572.1 - 4.3e-93 312.3 23.8 4.9e-93 312.1 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG19572.1 - 1.3e-23 83.3 31.6 6.3e-21 74.4 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG19572.1 - 6.8e-08 31.3 21.4 3.4e-05 22.4 4.6 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Pkinase PF00069.20 EKG19573.1 - 1.9e-53 181.2 0.0 4e-53 180.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HR1 PF02185.11 EKG19573.1 - 3.3e-32 110.0 10.8 4.6e-19 67.9 3.0 2.4 2 0 0 2 2 2 2 Hr1 repeat Pkinase_Tyr PF07714.12 EKG19573.1 - 2.2e-29 102.3 0.0 4.9e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EKG19573.1 - 1.5e-19 69.4 36.0 1e-11 44.3 8.1 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EKG19573.1 - 1.8e-13 50.7 2.0 6.4e-13 49.0 1.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EKG19573.1 - 0.028 13.3 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.1 EKG19573.1 - 0.035 14.1 2.6 0.056 13.4 0.3 2.2 2 0 0 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.11 EKG19573.1 - 0.58 10.0 18.7 0.51 10.2 3.3 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger PAT1 PF09770.4 EKG19573.1 - 6.5 4.8 42.1 0.045 12.0 23.4 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 EKG19574.1 - 8.1e-24 83.8 0.0 1.3e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG19574.1 - 5.7e-05 22.9 7.6 0.00011 21.9 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EKG19576.1 - 1.5e-35 122.6 0.0 2.3e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PS-DH PF14765.1 EKG19577.1 - 3e-09 36.4 0.0 3.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EKG19578.1 - 0.00038 19.3 0.0 0.0041 15.9 0.0 2.1 1 1 0 1 1 1 1 Condensation domain AATase PF07247.7 EKG19578.1 - 0.2 10.1 0.0 0.43 9.0 0.0 1.5 1 1 0 1 1 1 0 Alcohol acetyltransferase ADH_zinc_N PF00107.21 EKG19579.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SnoaL_3 PF13474.1 EKG19580.1 - 1.8e-10 40.9 0.1 1.6e-09 37.8 0.0 2.0 1 1 1 2 2 2 1 SnoaL-like domain DUF4440 PF14534.1 EKG19580.1 - 0.00031 20.9 0.1 0.0007 19.7 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) CaMKII_AD PF08332.5 EKG19580.1 - 0.0058 16.5 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association polyprenyl_synt PF00348.12 EKG19581.1 - 0.003 16.4 0.1 0.038 12.8 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase p450 PF00067.17 EKG19583.1 - 4e-23 81.6 0.0 1.2e-22 80.1 0.0 1.6 1 1 1 2 2 2 1 Cytochrome P450 adh_short PF00106.20 EKG19585.1 - 3.2e-15 56.4 1.6 5.5e-15 55.6 1.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG19585.1 - 5.1e-14 52.6 0.2 7.3e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG19585.1 - 0.003 17.2 3.5 0.0087 15.7 2.1 2.1 1 1 1 2 2 2 1 KR domain DUF4247 PF14042.1 EKG19585.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4247) p450 PF00067.17 EKG19586.1 - 8.6e-23 80.5 0.0 1.2e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EKG19587.1 - 1e-13 50.5 0.0 1.3e-08 33.7 0.0 3.0 2 1 0 2 2 2 2 Transferase family MFS_1 PF07690.11 EKG19587.1 - 9.5e-06 24.5 35.2 3.1e-05 22.8 13.0 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily p450 PF00067.17 EKG19588.1 - 1.5e-54 185.2 0.0 2e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EKG19589.1 - 4.5e-14 52.1 0.0 1.3e-13 50.6 0.0 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DegQ PF08181.6 EKG19589.1 - 0.22 11.2 0.5 0.38 10.4 0.4 1.3 1 0 0 1 1 1 0 DegQ (SacQ) family Acyl-CoA_dh_1 PF00441.19 EKG19592.1 - 5e-34 117.5 1.2 7.4e-34 117.0 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EKG19592.1 - 2.7e-21 74.8 1.0 4.5e-21 74.1 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EKG19592.1 - 5.2e-15 56.0 0.6 3.4e-14 53.3 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EKG19592.1 - 4.2e-08 33.5 0.4 7.5e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TetR_N PF00440.18 EKG19592.1 - 0.11 12.1 0.0 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Fungal_trans PF04082.13 EKG19593.1 - 7.6e-36 123.3 0.2 1.5e-35 122.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG19593.1 - 0.0002 21.1 15.5 0.00038 20.3 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EKG19593.1 - 0.5 8.5 6.4 0.8 7.8 4.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_fiss_reg PF05308.6 EKG19593.1 - 0.66 9.3 11.2 0.97 8.7 6.5 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator FAD_binding_4 PF01565.18 EKG19594.1 - 2.2e-22 79.0 1.6 3.5e-22 78.3 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG19594.1 - 0.002 17.9 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Shugoshin_N PF07558.6 EKG19595.1 - 0.0029 17.2 2.4 0.0094 15.6 0.9 2.4 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Cu-oxidase_3 PF07732.10 EKG19596.1 - 2.9e-45 152.7 3.6 6.9e-42 141.9 1.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG19596.1 - 1.2e-39 134.9 10.9 3.4e-34 117.3 1.2 4.0 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EKG19596.1 - 3.3e-32 111.6 0.9 2.2e-31 108.8 0.3 2.6 2 1 0 2 2 2 1 Multicopper oxidase UCH PF00443.24 EKG19598.1 - 0.017 14.2 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Cerato-platanin PF07249.7 EKG19600.1 - 1.1e-52 177.0 0.2 1.3e-52 176.8 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin ATP-synt_10 PF05176.9 EKG19601.1 - 1.4e-55 188.2 0.0 1.6e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 EKG19602.1 - 5.4e-15 55.2 4.6 1.2e-14 54.0 0.1 2.8 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.6 EKG19602.1 - 0.024 15.0 4.9 0.026 14.9 1.3 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal P16-Arc PF04699.9 EKG19602.1 - 0.034 14.1 0.9 0.057 13.4 0.3 1.5 1 1 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) STAT_alpha PF01017.15 EKG19602.1 - 0.071 12.8 3.3 0.95 9.1 1.0 2.5 1 1 0 2 2 2 0 STAT protein, all-alpha domain Laminin_II PF06009.7 EKG19602.1 - 0.088 12.5 6.5 1.9 8.2 3.5 2.7 1 1 0 2 2 2 0 Laminin Domain II Snf7 PF03357.16 EKG19602.1 - 0.18 11.1 3.8 0.19 11.0 0.8 1.9 1 1 1 2 2 2 0 Snf7 Snapin_Pallidin PF14712.1 EKG19602.1 - 0.19 12.0 7.4 0.13 12.5 3.4 2.0 2 0 0 2 2 2 0 Snapin/Pallidin USP8_interact PF08941.5 EKG19602.1 - 0.2 10.9 0.9 0.8 9.0 0.3 2.1 2 0 0 2 2 2 0 USP8 interacting Surfac_D-trimer PF09006.6 EKG19602.1 - 0.31 10.8 1.5 0.73 9.6 0.1 2.3 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation MbeD_MobD PF04899.7 EKG19602.1 - 1 9.3 0.0 1 9.3 0.0 3.3 3 1 1 4 4 4 0 MbeD/MobD like APG6 PF04111.7 EKG19602.1 - 1 8.3 5.3 0.92 8.4 2.9 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 Syntaxin_2 PF14523.1 EKG19602.1 - 1.6 8.8 6.4 24 5.0 0.1 3.1 1 1 1 2 2 2 0 Syntaxin-like protein CorA PF01544.13 EKG19602.1 - 1.6 7.6 9.9 1.5 7.7 5.4 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EKG19602.1 - 1.6 8.2 6.4 2.7 7.5 4.4 1.5 1 0 0 1 1 1 0 IncA protein FliT PF05400.8 EKG19602.1 - 8.2 6.9 12.9 3.8 7.9 5.6 2.5 2 1 1 3 3 3 0 Flagellar protein FliT Ribosomal_L29 PF00831.18 EKG19603.1 - 3.3e-19 68.3 0.9 3.3e-19 68.3 0.6 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein RsmJ PF04378.8 EKG19603.1 - 0.028 13.4 0.2 0.034 13.1 0.1 1.1 1 0 0 1 1 1 0 Ribosomal RNA small subunit methyltransferase D, RsmJ Ribosomal_S9 PF00380.14 EKG19603.1 - 0.03 14.5 1.8 0.039 14.1 1.2 1.4 1 1 0 1 1 1 0 Ribosomal protein S9/S16 SPATA24 PF15175.1 EKG19603.1 - 0.035 13.7 3.1 0.044 13.4 2.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 Aminotran_4 PF01063.14 EKG19604.1 - 2.6e-30 105.5 0.0 3.8e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EKG19605.1 - 4.8e-18 65.2 0.0 1.1e-17 64.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19605.1 - 1.4e-10 40.6 0.0 7.1e-10 38.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Tubulin PF00091.20 EKG19606.1 - 2.6e-73 246.4 0.0 4.1e-73 245.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKG19606.1 - 1.2e-48 164.2 0.0 2.2e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EKG19606.1 - 1e-05 25.5 0.0 2.5e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EKG19606.1 - 0.044 13.2 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Ank_2 PF12796.2 EKG19607.1 - 7.8e-18 64.6 0.8 1.2e-06 28.8 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG19607.1 - 1.4e-13 50.5 1.3 0.00028 21.0 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG19607.1 - 1.6e-12 47.5 3.8 0.0032 17.9 0.0 6.0 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EKG19607.1 - 1.2e-11 43.7 13.4 0.018 14.8 0.1 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 EKG19607.1 - 2e-10 39.8 13.4 0.13 12.5 0.0 6.8 7 0 0 7 7 7 4 Ankyrin repeat NACHT PF05729.7 EKG19607.1 - 0.00031 20.4 0.0 0.00081 19.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Thymidylate_kin PF02223.12 EKG19607.1 - 0.016 14.5 0.0 0.061 12.6 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_22 PF13401.1 EKG19607.1 - 0.12 12.4 0.1 2.1 8.4 0.0 2.6 1 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EKG19607.1 - 0.2 11.5 0.0 0.49 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EKG19608.1 - 7.4e-37 126.8 31.2 7.4e-37 126.8 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19610.1 - 1.5e-98 330.3 23.2 1.7e-98 330.1 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG19610.1 - 1.8e-33 115.7 28.0 9.6e-24 83.7 3.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG19610.1 - 0.00022 19.7 27.4 0.0013 17.2 4.1 3.3 1 1 2 3 3 3 2 MFS/sugar transport protein Peptidase_A4 PF01828.12 EKG19611.1 - 1.8e-84 281.9 9.2 5e-39 133.5 1.6 3.4 3 0 0 3 3 3 3 Peptidase A4 family RabGAP-TBC PF00566.13 EKG19612.1 - 1.1e-46 159.0 0.0 1.7e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ORC6 PF05460.8 EKG19613.1 - 4.7e-05 22.6 0.0 5.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Abhydrolase_3 PF07859.8 EKG19614.1 - 4e-40 137.6 0.0 4.8e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG19614.1 - 7.4e-09 34.8 0.3 1.5e-08 33.7 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EKG19614.1 - 0.00027 19.7 0.0 0.00035 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EKG19614.1 - 0.0012 18.6 0.5 0.0015 18.3 0.4 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG19614.1 - 0.0049 16.1 0.2 0.011 14.9 0.1 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EKG19614.1 - 0.029 13.2 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EKG19614.1 - 0.099 12.5 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 EKG19616.1 - 2.4e-35 121.9 22.4 1.2e-22 80.0 3.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG19616.1 - 4.2e-27 94.7 35.0 1.7e-25 89.5 21.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 EKG19617.1 - 2.7e-06 27.2 8.6 5.9e-06 26.0 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EKG19617.1 - 5.6e-05 22.3 0.2 5.6e-05 22.3 0.1 1.8 2 0 0 2 2 2 1 Aflatoxin regulatory protein bZIP_1 PF00170.16 EKG19618.1 - 0.019 14.9 1.0 0.022 14.7 0.7 1.1 1 0 0 1 1 1 0 bZIP transcription factor p450 PF00067.17 EKG19619.1 - 2.9e-44 151.3 0.0 4.3e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Propeptide_C1 PF08127.8 EKG19619.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C1 propeptide TRI5 PF06330.6 EKG19621.1 - 1.9e-05 23.5 0.0 2.3e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) IDO PF01231.13 EKG19622.1 - 0.0046 15.4 1.8 0.031 12.7 0.1 2.2 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase AAA PF00004.24 EKG19623.1 - 1.8e-17 63.7 0.0 3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG19623.1 - 0.00041 20.0 0.0 0.00089 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKG19623.1 - 0.0005 20.1 0.4 0.0028 17.6 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EKG19623.1 - 0.0017 18.0 0.2 0.0041 16.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EKG19623.1 - 0.0049 17.0 0.3 0.17 11.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EKG19623.1 - 0.019 14.0 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EKG19623.1 - 0.026 15.3 0.0 0.026 15.3 0.0 3.4 3 3 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EKG19623.1 - 0.028 14.7 0.0 0.11 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EKG19623.1 - 0.063 13.1 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EKG19623.1 - 0.085 13.1 0.9 0.36 11.1 0.7 2.1 1 1 0 1 1 1 0 AAA domain DUF3402 PF11882.3 EKG19624.1 - 1.3e-145 485.5 0.0 1.7e-145 485.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EKG19624.1 - 5.3e-80 268.3 0.0 7.6e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Glyco_hydro_43 PF04616.9 EKG19625.1 - 4e-28 98.3 0.1 1.5e-27 96.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 HLH PF00010.21 EKG19626.1 - 9.1e-13 47.6 0.4 1.7e-12 46.7 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pox_A30L_A26L PF06086.7 EKG19626.1 - 0.054 12.9 0.1 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein Cellulase PF00150.13 EKG19627.1 - 4.3e-18 65.4 0.2 4.3e-18 65.4 0.2 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) UvdE PF03851.9 EKG19627.1 - 0.16 10.9 0.1 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 UV-endonuclease UvdE Matrilin_ccoil PF10393.4 EKG19628.1 - 0.024 14.0 0.1 0.059 12.7 0.1 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2317 PF10079.4 EKG19628.1 - 1.7 7.2 13.1 2.4 6.6 9.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) V_ATPase_I PF01496.14 EKG19628.1 - 3.2 5.4 6.9 4.2 5.0 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GRP PF07172.6 EKG19628.1 - 9.6 6.7 18.7 30 5.1 12.4 2.3 2 0 0 2 2 2 0 Glycine rich protein family Ank_5 PF13857.1 EKG19629.1 - 1e-05 25.6 0.0 3.1e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EKG19629.1 - 2.9e-05 24.3 0.0 5.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKG19629.1 - 0.00015 21.6 0.1 0.0012 18.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 EKG19629.1 - 0.00021 20.9 0.0 0.00042 19.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EKG19629.1 - 0.1 13.1 0.0 0.34 11.4 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) JmjC PF02373.17 EKG19631.1 - 2.6e-37 127.5 0.6 5.8e-37 126.4 0.4 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EKG19631.1 - 1.4e-19 70.1 3.9 2.7e-19 69.2 2.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EKG19631.1 - 2.3e-19 69.3 5.9 5.8e-19 68.0 4.1 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EKG19631.1 - 1e-08 34.5 1.0 2.5e-08 33.3 0.7 1.7 1 0 0 1 1 1 1 jmjN domain Med26 PF08711.6 EKG19633.1 - 1.4e-14 53.3 0.1 2.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Iron_permease PF04120.7 EKG19633.1 - 0.037 13.6 0.9 0.07 12.7 0.6 1.4 1 0 0 1 1 1 0 Low affinity iron permease Nup54 PF13874.1 EKG19634.1 - 1.1e-40 138.6 3.2 1.1e-40 138.6 2.2 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EKG19634.1 - 6.9e-05 23.0 45.8 0.0085 16.3 20.3 2.2 1 1 1 2 2 2 2 Nucleoporin FG repeat region RAB3GAP2_N PF14655.1 EKG19634.1 - 0.05 12.5 1.0 0.085 11.8 0.7 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PA28_beta PF02252.13 EKG19634.1 - 0.14 11.6 0.2 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit FUSC PF04632.7 EKG19634.1 - 4.8 5.4 6.5 7.4 4.8 4.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HTH_12 PF08461.5 EKG19634.1 - 8.1 6.2 6.8 1.4 8.7 0.4 2.5 2 1 1 3 3 3 0 Ribonuclease R winged-helix domain CHCH PF06747.8 EKG19635.1 - 1.8e-07 30.8 5.1 1.8e-07 30.8 3.5 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EKG19635.1 - 0.21 11.4 11.1 0.6 9.9 2.3 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EKG19635.1 - 0.52 10.3 9.7 0.65 10.0 3.8 2.7 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 HLH PF00010.21 EKG19636.1 - 3.1e-11 42.7 0.1 8.8e-11 41.3 0.1 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain CENP-Q PF13094.1 EKG19636.1 - 0.059 13.3 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SERTA PF06031.8 EKG19637.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 SERTA motif p450 PF00067.17 EKG19639.1 - 3.8e-36 124.5 0.0 4.2e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG19640.1 - 7.1e-05 21.5 0.0 8.5e-05 21.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 EKG19641.1 - 2e-10 40.3 0.0 3.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG19641.1 - 1.1e-07 31.4 0.0 2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 EKG19642.1 - 4.5e-21 75.1 0.2 6e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG19642.1 - 9.8e-16 58.2 0.0 1.5e-15 57.6 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG19642.1 - 6.1e-05 22.5 0.2 0.00029 20.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EKG19642.1 - 0.0006 18.9 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EKG19642.1 - 0.0072 15.0 0.1 0.011 14.4 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 EKG19643.1 - 6.4e-47 160.1 0.0 7.5e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EKG19644.1 - 9.1e-49 165.9 1.1 1.2e-48 165.5 0.8 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EKG19644.1 - 6.3e-27 94.1 0.0 1.1e-17 63.8 0.0 2.3 1 1 1 2 2 2 2 Condensation domain PP-binding PF00550.20 EKG19644.1 - 9.2e-09 35.4 1.6 1.6e-08 34.6 0.0 2.3 3 0 0 3 3 3 1 Phosphopantetheine attachment site RNA_pol_Rpb2_6 PF00562.23 EKG19645.1 - 7.8e-120 400.1 0.0 1.1e-119 399.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EKG19645.1 - 7e-48 162.2 0.3 1.4e-47 161.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EKG19645.1 - 1.9e-28 98.4 0.5 5.7e-28 96.9 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EKG19645.1 - 1.1e-25 90.1 0.9 4e-25 88.3 0.7 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EKG19645.1 - 2.2e-21 75.4 0.5 4.5e-21 74.4 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EKG19645.1 - 8.5e-19 67.0 0.1 2e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EKG19645.1 - 1.8e-12 47.0 0.8 3.8e-12 45.9 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Aldo_ket_red PF00248.16 EKG19646.1 - 5.2e-51 173.1 0.1 6.8e-51 172.7 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family E1-E2_ATPase PF00122.15 EKG19647.1 - 1.2e-63 214.2 8.3 3e-63 212.9 5.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKG19647.1 - 2.2e-22 80.5 0.0 5.4e-22 79.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG19647.1 - 4e-13 49.9 0.0 9.8e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKG19647.1 - 1.1e-11 44.0 0.0 2.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EKG19647.1 - 0.003 17.1 1.5 0.003 17.1 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG19647.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Trypsin_2 PF13365.1 EKG19648.1 - 0.057 13.4 0.0 0.38 10.7 0.0 2.2 2 1 0 2 2 2 0 Trypsin-like peptidase domain Cauli_VI PF01693.11 EKG19649.1 - 3.1e-35 119.9 5.5 8.3e-19 67.3 0.3 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EKG19649.1 - 2.1e-21 76.6 0.0 4.9e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 RNase H 6PF2K PF01591.13 EKG19650.1 - 4.5e-64 215.5 0.0 1.5e-47 161.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EKG19650.1 - 4.2e-28 98.4 0.1 6.4e-27 94.5 0.0 2.4 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EKG19650.1 - 0.0021 17.9 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Peptidase_M43 PF05572.8 EKG19652.1 - 1.1e-14 54.3 0.1 2.2e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EKG19652.1 - 1.9e-06 27.9 0.2 3.2e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EKG19652.1 - 0.0004 20.4 3.2 0.0009 19.3 2.3 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EKG19652.1 - 0.0015 19.0 0.6 0.004 17.6 0.4 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EKG19652.1 - 0.004 16.8 0.0 0.0064 16.2 0.0 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EKG19652.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 EKG19652.1 - 0.049 13.1 1.6 0.11 12.0 1.1 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like CDC50 PF03381.10 EKG19653.1 - 9e-102 339.9 0.1 1.2e-101 339.5 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SWIRM PF04433.12 EKG19654.1 - 5.7e-16 58.4 0.1 2.4e-14 53.1 0.0 2.3 2 0 0 2 2 2 2 SWIRM domain Abhydrolase_5 PF12695.2 EKG19657.1 - 0.00071 19.3 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG19657.1 - 0.031 14.1 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family WLM PF08325.5 EKG19658.1 - 5.7e-40 137.1 0.0 1.1e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EKG19658.1 - 0.0014 18.4 0.1 0.0025 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EKG19658.1 - 0.0041 16.7 0.4 0.0073 15.9 0.3 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EKG19658.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily ubiquitin PF00240.18 EKG19658.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Myb_DNA-binding PF00249.26 EKG19659.1 - 2.2e-10 40.4 0.8 1.6e-09 37.6 0.1 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG19659.1 - 3.7e-07 30.1 0.9 1e-06 28.7 0.5 1.7 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EKG19659.1 - 0.022 14.8 2.7 0.046 13.8 1.9 1.6 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain TPR_MLP1_2 PF07926.7 EKG19659.1 - 0.04 13.6 0.6 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Myb_DNA-bind_5 PF13873.1 EKG19659.1 - 0.042 13.7 0.6 14 5.6 0.1 2.7 1 1 2 3 3 3 0 Myb/SANT-like DNA-binding domain Ring_hydroxyl_A PF00848.14 EKG19659.1 - 0.18 11.4 0.3 1.8 8.1 0.0 1.9 1 1 1 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) Es2 PF09751.4 EKG19660.1 - 1.2e-94 318.0 0.1 2e-94 317.3 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein Es2 eIF-6 PF01912.13 EKG19662.1 - 1.7e-83 278.6 1.8 1.9e-83 278.4 0.9 1.3 2 0 0 2 2 2 1 eIF-6 family Phage_holin_6 PF10746.4 EKG19662.1 - 0.12 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Phage holin family 6 Claudin_2 PF13903.1 EKG19664.1 - 0.0077 15.9 5.9 0.0077 15.9 4.1 1.9 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction IncA PF04156.9 EKG19664.1 - 3.2 7.3 6.7 5.1 6.6 4.6 1.4 1 0 0 1 1 1 0 IncA protein Baculo_p74 PF04583.7 EKG19664.1 - 7.2 5.7 8.4 12 5.0 5.9 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region XPC-binding PF09280.6 EKG19665.1 - 8.7e-24 82.7 12.4 1.7e-23 81.8 8.6 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EKG19665.1 - 3.7e-21 74.2 0.5 5.6e-21 73.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EKG19665.1 - 3.4e-16 58.5 1.9 3.2e-08 33.1 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EKG19665.1 - 2.8e-09 36.5 0.6 4.5e-09 35.8 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EKG19665.1 - 0.00046 20.0 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EKG19665.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 MCM N-terminal domain Ubiquitin_2 PF14560.1 EKG19665.1 - 0.035 14.3 0.1 0.079 13.2 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.5 EKG19665.1 - 0.045 13.3 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF2407 PF10302.4 EKG19665.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 EKG19665.1 - 0.068 13.0 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PepSY_2 PF13670.1 EKG19668.1 - 0.081 12.8 6.7 0.15 11.9 4.0 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 EKG19668.1 - 0.73 10.2 10.2 0.087 13.2 3.3 2.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein Herpes_capsid PF06112.6 EKG19668.1 - 7.8 6.5 11.0 0.78 9.7 2.8 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein COX4 PF02936.9 EKG19669.1 - 6.1e-47 158.9 0.1 7.8e-47 158.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Gp_dh_C PF02800.15 EKG19670.1 - 2.6e-74 247.9 0.0 3.8e-74 247.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EKG19670.1 - 1.9e-60 203.1 0.1 3.1e-60 202.5 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EKG19670.1 - 0.041 13.7 0.2 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EKG19670.1 - 0.13 11.3 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hist_deacetyl PF00850.14 EKG19671.1 - 3.7e-97 325.3 0.3 3.7e-97 325.3 0.2 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 EKG19671.1 - 2.1e-35 121.7 0.0 3.2e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain NIF PF03031.13 EKG19672.1 - 4.4e-20 71.9 0.1 1.1e-19 70.6 0.1 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF3846 PF12957.2 EKG19672.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) AHS2 PF02626.10 EKG19674.1 - 4.3e-70 236.0 0.0 6.5e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EKG19674.1 - 8.9e-56 188.5 0.0 1.7e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EKG19674.1 - 1.6e-34 118.2 0.3 3.9e-34 117.0 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EKG19674.1 - 8.9e-33 112.4 0.0 1.9e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 EKG19674.1 - 1.3e-28 99.8 0.0 6e-28 97.6 0.0 1.9 2 0 0 2 2 2 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 EKG19674.1 - 4.3e-13 49.4 0.2 1.1e-12 48.1 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG19674.1 - 2.6e-08 32.9 0.0 5.2e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EKG19674.1 - 6.2e-07 28.9 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 EKG19674.1 - 6.6e-06 25.6 0.7 0.00046 19.7 0.2 3.4 3 1 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_5 PF13549.1 EKG19674.1 - 0.0025 17.0 0.0 0.0051 16.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EKG19674.1 - 0.032 13.8 3.2 2.6 7.7 0.1 3.4 3 0 0 3 3 3 0 Biotin-lipoyl like ATP-grasp PF02222.17 EKG19674.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 EKG19674.1 - 0.24 10.8 0.0 0.51 9.7 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain LamB_YcsF PF03746.11 EKG19675.1 - 8e-59 198.6 0.0 3.2e-43 147.5 0.0 2.0 2 0 0 2 2 2 2 LamB/YcsF family CorA PF01544.13 EKG19678.1 - 4.5e-07 29.1 1.2 3.1e-05 23.1 0.8 2.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EKG19679.1 - 1.3e-21 76.9 0.0 8.2e-21 74.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19679.1 - 1.2e-12 47.4 0.0 5.6e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Oxidored_FMN PF00724.15 EKG19680.1 - 2.2e-24 86.1 0.0 2.5e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abi PF02517.11 EKG19682.1 - 3.7e-14 52.6 8.8 3.7e-14 52.6 6.1 3.0 3 1 1 4 4 4 1 CAAX protease self-immunity SET PF00856.23 EKG19683.1 - 7.4e-23 81.6 0.3 1.9e-21 77.0 0.1 3.1 2 1 0 2 2 2 1 SET domain SRI PF08236.6 EKG19683.1 - 1.6e-14 53.6 9.1 3.7e-14 52.4 6.3 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EKG19683.1 - 0.0011 18.4 0.1 0.0031 16.9 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.21 EKG19683.1 - 0.0039 17.0 0.3 0.011 15.5 0.2 1.9 1 0 0 1 1 1 1 WW domain Aminotran_3 PF00202.16 EKG19684.1 - 5.8e-99 331.1 0.0 7.1e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EKG19684.1 - 0.061 12.2 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II AA_permease_2 PF13520.1 EKG19685.1 - 1e-41 142.9 44.8 1.3e-41 142.5 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG19685.1 - 3.6e-29 101.4 40.4 4.3e-29 101.1 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease KRE9 PF05390.6 EKG19685.1 - 0.13 12.6 1.8 1.9 8.8 0.3 2.4 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 Ammonium_transp PF00909.16 EKG19686.1 - 2.2e-73 247.0 18.5 2.5e-73 246.8 12.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PepSY_TM_2 PF13703.1 EKG19686.1 - 4.2 7.6 9.0 2 8.6 0.4 3.4 3 1 0 3 3 3 0 PepSY-associated TM helix PT-HINT PF07591.6 EKG19687.1 - 0.095 12.5 0.0 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Pretoxin HINT domain AMP-binding PF00501.23 EKG19689.1 - 5.2e-32 110.7 0.0 7.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_S10 PF00450.17 EKG19690.1 - 4.7e-33 114.9 0.0 6e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.19 EKG19694.1 - 2.1e-15 56.2 2.1 2.8e-15 55.8 1.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG19694.1 - 2e-11 43.2 8.0 2.6e-11 42.8 5.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG19694.1 - 6.5e-05 21.4 0.7 7.5e-05 21.3 0.5 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 EKG19694.1 - 0.013 13.7 1.3 0.017 13.3 0.9 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_2_C PF02836.12 EKG19697.1 - 6.5e-101 337.1 0.0 8.3e-101 336.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EKG19697.1 - 2.4e-56 189.8 0.2 2.4e-56 189.8 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.12 EKG19697.1 - 1.8e-39 135.4 0.0 2.9e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2 PF00703.16 EKG19697.1 - 9.8e-12 45.3 0.0 2.7e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EKG19697.1 - 0.025 14.8 0.3 0.12 12.6 0.0 2.3 3 0 0 3 3 3 0 Beta-galactosidase jelly roll domain GST_N_3 PF13417.1 EKG19698.1 - 0.00021 21.4 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Fungal_trans_2 PF11951.3 EKG19699.1 - 1.6e-42 145.4 0.1 2.9e-23 82.1 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain SBP_bac_6 PF13343.1 EKG19700.1 - 8.7e-19 67.7 0.3 1.4e-18 67.1 0.2 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EKG19700.1 - 8.2e-12 45.2 0.0 2.4e-11 43.7 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EKG19700.1 - 1.8e-06 27.9 10.5 1.1e-05 25.3 6.6 2.3 2 1 0 2 2 2 1 Bacterial extracellular solute-binding protein Sugar_tr PF00083.19 EKG19701.1 - 9.1e-71 238.7 20.6 1e-70 238.5 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG19701.1 - 3.2e-14 52.4 15.7 3.2e-14 52.4 10.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EKG19702.1 - 6.6e-30 103.9 0.8 9e-30 103.5 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG19702.1 - 6.9e-09 35.4 8.9 1.9e-08 34.0 6.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMP-TENI PF02581.12 EKG19702.1 - 0.028 13.5 0.4 0.047 12.8 0.0 1.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI NAD_binding_6 PF08030.7 EKG19703.1 - 2.2e-16 60.1 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EKG19703.1 - 3.1e-06 27.7 0.0 0.0032 18.0 0.0 2.2 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 EKG19703.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Peptidase_M43 PF05572.8 EKG19704.1 - 2.9e-21 75.6 0.7 5.4e-21 74.8 0.5 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EKG19704.1 - 2e-05 24.6 3.1 3.5e-05 23.8 2.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EKG19704.1 - 6.4e-05 23.0 5.3 0.00011 22.2 3.7 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EKG19704.1 - 0.0001 22.8 0.5 0.00035 21.0 0.4 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EKG19704.1 - 0.00025 20.6 2.9 0.00046 19.7 2.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.11 EKG19704.1 - 0.0025 17.5 2.7 0.011 15.4 1.8 2.1 1 1 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M57 PF12388.3 EKG19704.1 - 0.004 16.4 0.3 0.0067 15.7 0.2 1.5 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EKG19704.1 - 0.0086 15.8 0.1 0.015 15.0 0.1 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EKG19704.1 - 0.068 12.0 0.2 0.1 11.4 0.2 1.4 1 0 0 1 1 1 0 Peptidase M66 PTR2 PF00854.16 EKG19705.1 - 5.9e-53 179.9 11.2 8.2e-53 179.5 7.7 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 EKG19705.1 - 0.0094 14.6 31.8 0.021 13.5 18.0 3.2 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease PF00324.16 EKG19706.1 - 1.3e-135 452.5 35.8 1.5e-135 452.2 24.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG19706.1 - 1e-42 146.1 39.1 1.3e-42 145.8 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease Orai-1 PF07856.7 EKG19706.1 - 0.0022 17.5 2.0 0.005 16.4 1.4 1.5 1 0 0 1 1 1 1 Mediator of CRAC channel activity Sec16_C PF12931.2 EKG19707.1 - 8.4e-102 340.7 0.0 1.2e-101 340.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EKG19707.1 - 2.6e-26 91.8 0.0 5.3e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PV-1 PF06637.6 EKG19707.1 - 0.65 8.4 0.0 1.3 7.5 0.0 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Tsp45I PF06300.7 EKG19707.1 - 1.3 8.4 0.7 2.2 7.6 0.1 1.6 2 0 0 2 2 2 0 Tsp45I type II restriction enzyme E1-E2_ATPase PF00122.15 EKG19708.1 - 1.6e-18 66.5 0.0 4.3e-18 65.1 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKG19708.1 - 5e-15 56.5 0.0 1.7e-14 54.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG19708.1 - 4.1e-09 36.8 0.2 1.2e-08 35.3 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG19708.1 - 2.5e-05 24.1 0.0 8.2e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EKG19708.1 - 0.0029 17.2 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase QCR10 PF09796.4 EKG19710.1 - 8e-29 99.0 0.4 1e-28 98.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Proteasome PF00227.21 EKG19711.1 - 9e-55 184.9 0.0 1.1e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EKG19711.1 - 1.2e-13 50.0 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EKG19711.1 - 0.077 12.6 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) FAD_binding_3 PF01494.14 EKG19712.1 - 4e-23 82.0 0.0 2.7e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EKG19712.1 - 2.2e-05 23.7 0.3 0.085 11.9 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EKG19712.1 - 0.01 16.2 4.5 0.12 12.8 0.1 3.4 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG19712.1 - 0.04 13.9 0.1 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Carn_acyltransf PF00755.15 EKG19714.1 - 3.6e-166 553.7 0.0 3.4e-152 507.5 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Rad51 PF08423.6 EKG19715.1 - 3.2e-18 65.5 0.0 4.9e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EKG19715.1 - 1.4e-10 40.9 0.2 3.1e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EKG19715.1 - 6.9e-05 22.0 0.0 0.00014 21.0 0.0 1.5 1 1 0 1 1 1 1 KaiC RecA PF00154.16 EKG19715.1 - 0.00041 19.5 0.2 0.073 12.1 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_22 PF13401.1 EKG19715.1 - 0.0034 17.5 0.1 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EKG19715.1 - 0.096 12.1 0.6 0.43 10.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EKG19715.1 - 0.16 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 EKG19716.1 - 5.2e-135 450.2 3.5 6.1e-135 449.9 2.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 EKG19716.1 - 0.0054 16.8 0.0 0.016 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sipho_tail PF05709.6 EKG19716.1 - 0.073 12.1 0.2 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 Phage tail protein RuvB_N PF05496.7 EKG19716.1 - 0.075 12.0 0.5 0.2 10.6 0.4 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ATG16 PF08614.6 EKG19717.1 - 0.00016 21.5 12.1 0.00016 21.5 8.4 7.7 3 2 6 9 9 9 4 Autophagy protein 16 (ATG16) DUF2730 PF10805.3 EKG19717.1 - 0.054 13.2 23.3 0.31 10.7 1.4 7.6 5 3 3 8 8 8 0 Protein of unknown function (DUF2730) Reo_sigmaC PF04582.7 EKG19717.1 - 0.085 12.0 37.1 0.077 12.1 0.3 6.3 4 2 1 7 7 7 0 Reovirus sigma C capsid protein HOOK PF05622.7 EKG19718.1 - 8.4e-09 33.8 82.6 1.3e-07 29.8 57.3 3.1 1 1 0 1 1 1 1 HOOK protein HALZ PF02183.13 EKG19718.1 - 0.013 15.2 1.2 0.013 15.2 0.9 7.7 9 1 0 9 9 9 0 Homeobox associated leucine zipper DUF4400 PF14348.1 EKG19718.1 - 0.021 14.2 2.2 0.1 11.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) DivIC PF04977.10 EKG19718.1 - 0.079 12.4 0.1 0.079 12.4 0.1 10.4 6 2 6 12 12 12 0 Septum formation initiator RCC1_2 PF13540.1 EKG19719.1 - 0.05 13.2 0.3 0.096 12.3 0.2 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat LPAM_1 PF08139.7 EKG19719.1 - 4 7.8 5.1 6.7 7.0 3.5 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site zf-C2HC_2 PF13913.1 EKG19720.1 - 9.5e-05 21.9 3.5 0.051 13.2 0.1 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type VHS PF00790.14 EKG19720.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 VHS domain RRN7 PF11781.3 EKG19720.1 - 0.0083 15.5 1.2 0.22 11.0 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_2 PF13639.1 EKG19720.1 - 0.042 13.6 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Ring finger domain CTD_bind PF04818.8 EKG19720.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase II-binding domain. zf-C2H2 PF00096.21 EKG19720.1 - 5.7 7.5 5.4 21 5.7 0.2 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Rad50_zn_hook PF04423.9 EKG19720.1 - 6.4 6.3 5.6 32 4.1 0.1 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif ADK PF00406.17 EKG19721.1 - 5.9e-60 201.5 0.0 7.8e-60 201.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EKG19721.1 - 2.1e-14 52.8 0.0 4.9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EKG19721.1 - 4.9e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG19721.1 - 0.00041 20.6 0.0 0.00094 19.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG19721.1 - 0.00049 20.9 0.2 0.0012 19.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKG19721.1 - 0.005 15.9 0.0 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EKG19721.1 - 0.024 13.8 0.1 0.039 13.1 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI COG2 PF06148.6 EKG19721.1 - 0.042 13.7 0.2 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Spc19 PF08287.6 EKG19721.1 - 0.068 12.7 0.2 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 Spc19 LSM14 PF12701.2 EKG19723.1 - 1e-34 118.2 0.0 1.8e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EKG19723.1 - 2.8e-20 72.7 1.1 6.3e-20 71.6 0.7 1.6 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EKG19723.1 - 3.2e-05 23.7 0.0 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain MDMPI_N PF11716.3 EKG19723.1 - 9.4 6.6 15.4 36 4.7 10.7 2.0 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Fork_head PF00250.13 EKG19724.1 - 0.0059 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Amidinotransf PF02274.12 EKG19724.1 - 0.045 12.8 0.0 0.079 12.0 0.0 1.4 1 1 0 1 1 1 0 Amidinotransferase Herpes_UL52 PF03121.10 EKG19724.1 - 0.058 13.1 0.1 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Mif2_N PF15624.1 EKG19725.1 - 9.7e-28 97.4 9.7 9.7e-28 97.4 6.7 5.7 2 2 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EKG19725.1 - 4.1e-20 71.5 0.1 7.1e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Abhydrolase_6 PF12697.2 EKG19726.1 - 7.7e-23 81.5 0.0 8.8e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG19726.1 - 3.5e-08 33.3 0.0 4.8e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EKG19726.1 - 0.00084 19.6 0.0 0.011 16.0 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.2 EKG19726.1 - 0.0034 16.3 0.1 0.0094 14.8 0.1 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EKG19726.1 - 0.012 15.1 0.0 0.029 13.9 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EKG19726.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.6 EKG19726.1 - 0.087 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase HET PF06985.6 EKG19727.1 - 0.00024 21.2 0.0 0.00051 20.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spore_III_AB PF09548.5 EKG19727.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PAF-AH_p_II PF03403.8 EKG19728.1 - 3.4e-11 42.0 0.1 9.3e-09 34.0 0.0 2.4 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EKG19728.1 - 7.5e-10 38.7 0.5 1.3e-09 37.9 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EKG19728.1 - 1.1e-05 24.4 0.0 1.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EKG19728.1 - 0.0078 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EKG19728.1 - 0.15 10.8 0.2 0.73 8.5 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase HET PF06985.6 EKG19732.1 - 6.5e-18 65.2 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABM PF03992.11 EKG19735.1 - 3.3e-05 23.8 0.2 0.00024 21.0 0.0 2.3 3 0 0 3 3 3 1 Antibiotic biosynthesis monooxygenase DUF2236 PF09995.4 EKG19739.1 - 0.013 14.8 0.1 0.028 13.6 0.1 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF1049 PF06305.6 EKG19739.1 - 0.83 9.1 2.7 1.7 8.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Pyr_redox_3 PF13738.1 EKG19740.1 - 2.3e-25 89.8 0.0 2e-24 86.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG19740.1 - 4.2e-09 36.2 0.1 1.9e-08 34.1 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG19740.1 - 3.1e-08 33.5 0.0 4e-05 23.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EKG19740.1 - 1.3e-05 24.2 0.1 0.0016 17.4 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EKG19740.1 - 3.6e-05 23.8 0.0 0.062 13.4 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EKG19740.1 - 0.0007 19.5 0.0 3.6 7.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG19740.1 - 0.0025 16.7 0.0 0.43 9.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.14 EKG19740.1 - 0.0053 15.9 0.0 0.048 12.8 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Malic_M PF03949.10 EKG19740.1 - 0.026 14.0 0.1 1.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain DUF498 PF04430.9 EKG19740.1 - 0.044 13.3 0.0 30 4.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) GIDA PF01134.17 EKG19740.1 - 0.07 11.9 0.1 9.1 5.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.16 EKG19740.1 - 0.071 12.9 0.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.13 EKG19740.1 - 0.1 12.5 0.3 26 4.8 0.0 3.7 4 0 0 4 4 4 0 TrkA-N domain p450 PF00067.17 EKG19741.1 - 1.1e-25 90.1 0.0 1.2e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 EKG19742.1 - 3e-07 30.8 0.0 8.5e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG19742.1 - 3.1e-06 27.5 0.0 1.3e-05 25.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG19742.1 - 4e-06 27.1 0.1 3.6e-05 24.0 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG19742.1 - 1.8e-05 24.3 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG19742.1 - 2.3e-05 24.1 0.0 3.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG19742.1 - 7.2e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EKG19742.1 - 0.0019 18.7 0.1 0.007 16.9 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG19742.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Condensation PF00668.15 EKG19743.1 - 2.6e-51 174.2 0.0 3.4e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 EKG19748.1 - 5.3e-51 173.5 0.5 9.1e-51 172.7 0.4 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_26 PF13659.1 EKG19748.1 - 0.1 12.6 1.3 0.32 11.0 0.1 2.4 3 0 0 3 3 3 0 Methyltransferase domain NMO PF03060.10 EKG19749.1 - 8.9e-12 44.7 0.0 9.8e-12 44.6 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase AMP-binding PF00501.23 EKG19750.1 - 4.8e-253 838.8 0.0 2.4e-83 279.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EKG19750.1 - 3.6e-77 259.1 0.0 3.7e-39 134.3 0.0 2.5 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EKG19750.1 - 1.4e-40 137.3 0.0 3.6e-12 46.3 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG19750.1 - 2.2e-19 70.1 1.3 7.2e-06 26.8 0.0 4.3 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EKG19750.1 - 0.00095 19.4 0.1 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 HxxPF-repeated domain WES_acyltransf PF03007.11 EKG19750.1 - 0.033 13.7 0.6 7.3 6.0 0.1 3.1 2 1 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Phage_Coat_Gp8 PF05371.7 EKG19750.1 - 0.059 12.9 0.4 6.3 6.4 0.0 2.8 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Ribosomal_L18_c PF14204.1 EKG19750.1 - 0.28 11.7 0.0 13 6.4 0.0 2.8 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region MFS_1 PF07690.11 EKG19753.1 - 1.9e-31 109.1 17.7 2.1e-31 108.9 12.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19753.1 - 8.3e-10 37.8 9.4 2.1e-09 36.5 6.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EKG19753.1 - 0.00069 18.1 6.4 0.065 11.6 2.2 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EKG19753.1 - 0.062 13.0 0.2 0.3 10.9 0.0 2.3 2 0 0 2 2 2 0 MFS_1 like family MFS_1 PF07690.11 EKG19754.1 - 2e-29 102.3 24.8 2e-29 102.3 17.2 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19754.1 - 5.9e-08 31.7 2.2 5.9e-08 31.7 1.5 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3438 PF11920.3 EKG19754.1 - 0.006 15.4 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3438) OATP PF03137.15 EKG19754.1 - 0.028 12.4 0.0 0.074 11.1 0.0 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2924 PF11149.3 EKG19754.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) TauD PF02668.11 EKG19755.1 - 1.8e-12 47.5 0.0 4.7e-08 33.0 0.0 2.0 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family Cupin_2 PF07883.6 EKG19756.1 - 2.7e-08 33.1 0.0 5.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Cupin domain SGL PF08450.7 EKG19756.1 - 3.6e-06 26.5 0.0 7.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Cupin_3 PF05899.7 EKG19756.1 - 0.084 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SGL PF08450.7 EKG19757.1 - 5.4e-27 94.7 0.1 3.1e-25 88.9 0.0 2.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EKG19757.1 - 0.00029 20.8 0.0 0.0012 18.7 0.0 2.1 2 0 0 2 2 2 1 Strictosidine synthase DUF839 PF05787.8 EKG19757.1 - 0.0085 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) Arylesterase PF01731.15 EKG19757.1 - 0.0099 15.8 0.4 0.053 13.5 0.0 2.5 4 0 0 4 4 4 1 Arylesterase PD40 PF07676.7 EKG19757.1 - 0.093 12.4 0.7 0.79 9.4 0.0 3.0 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat NHL PF01436.16 EKG19757.1 - 0.13 12.2 3.1 0.87 9.6 0.0 3.5 4 0 0 4 4 4 0 NHL repeat CBM_1 PF00734.13 EKG19759.1 - 2.7e-12 46.0 8.8 6.3e-12 44.9 6.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Pec_lyase_C PF00544.14 EKG19759.1 - 2e-11 43.7 0.4 3.3e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EKG19759.1 - 6.7e-07 29.1 1.2 1.4e-06 28.1 0.8 1.5 1 0 0 1 1 1 1 Right handed beta helix region CDC27 PF09507.5 EKG19759.1 - 0.25 10.5 7.1 0.33 10.1 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ashwin PF15323.1 EKG19759.1 - 2.6 8.0 5.7 4.2 7.2 4.0 1.3 1 0 0 1 1 1 0 Developmental protein Macoilin PF09726.4 EKG19759.1 - 3 6.0 7.5 2.8 6.0 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Pectinesterase PF01095.14 EKG19760.1 - 8.7e-19 67.1 1.7 1.2e-18 66.7 1.2 1.0 1 0 0 1 1 1 1 Pectinesterase DUF2784 PF10861.3 EKG19760.1 - 0.079 12.7 0.0 13 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF2784) Ribosomal_S5_C PF03719.10 EKG19760.1 - 0.14 11.4 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Glyco_hydro_2_N PF02837.13 EKG19762.1 - 4.6e-27 94.6 0.0 8.7e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EKG19762.1 - 2.9e-10 40.5 0.0 6e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EKG19762.1 - 1.1e-08 34.3 0.0 1.9e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BBE PF08031.7 EKG19765.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EKG19767.1 - 0.031 12.8 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.17 EKG19768.1 - 6.9e-27 94.0 0.0 7.7e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EKG19769.1 - 6.1e-11 41.6 0.0 9.1e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG19770.1 - 3e-35 121.6 58.3 4.9e-29 101.1 18.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19770.1 - 9.2e-06 24.4 35.9 0.017 13.7 6.4 2.9 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 EKG19770.1 - 0.00019 21.1 5.1 0.013 15.3 0.2 4.4 3 1 1 4 4 4 1 MFS_1 like family Tyrosinase PF00264.15 EKG19772.1 - 2e-50 172.0 1.3 2.3e-50 171.8 0.9 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase RPE65 PF03055.10 EKG19773.1 - 3e-10 39.2 0.0 8e-10 37.8 0.0 1.5 1 1 1 2 2 2 1 Retinal pigment epithelial membrane protein End_N_terminal PF12218.3 EKG19773.1 - 0.083 12.3 0.1 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase FAM165 PF14981.1 EKG19774.1 - 0.14 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 FAM165 family adh_short PF00106.20 EKG19775.1 - 3e-14 53.2 0.3 4e-14 52.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19775.1 - 3.2e-07 30.1 0.1 4.3e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 KR domain IF2_N PF04760.10 EKG19776.1 - 0.098 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Pyr_redox_3 PF13738.1 EKG19777.1 - 3.1e-25 89.4 0.0 5e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG19777.1 - 3.8e-14 51.8 0.0 5.8e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EKG19777.1 - 4.1e-08 32.5 0.1 1.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EKG19777.1 - 7.4e-08 32.5 0.0 9.9e-05 22.3 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EKG19777.1 - 5.3e-05 22.4 0.0 0.093 11.8 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EKG19777.1 - 0.0064 16.2 0.1 0.14 11.9 0.1 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EKG19777.1 - 0.0084 16.4 0.1 0.23 11.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EKG19777.1 - 0.017 15.0 0.1 0.92 9.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.10 EKG19777.1 - 0.028 14.2 0.0 0.25 11.1 0.0 2.3 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.1 EKG19777.1 - 0.032 14.2 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG19777.1 - 0.075 11.9 0.0 0.15 10.8 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EKG19777.1 - 0.079 12.6 0.0 0.32 10.6 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain COesterase PF00135.23 EKG19778.1 - 7.7e-08 31.4 2.2 1.6e-07 30.4 1.5 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG19778.1 - 2.1e-06 27.4 0.1 2.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 EKG19779.1 - 1.9e-08 33.4 0.6 3.6e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EKG19779.1 - 2.1e-05 24.5 1.7 2.1e-05 24.5 1.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EKG19779.1 - 2.3e-05 24.4 8.3 0.0016 18.6 1.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG19779.1 - 0.00022 21.3 7.8 0.015 15.6 1.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EKG19779.1 - 0.0038 17.0 2.7 0.013 15.3 1.9 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger COX_ARM PF06481.9 EKG19780.1 - 0.11 12.1 0.2 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 COX Aromatic Rich Motif MFS_1 PF07690.11 EKG19781.1 - 6.2e-49 166.5 51.0 1.8e-48 165.0 35.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG19781.1 - 2.5e-17 62.3 19.6 3.5e-17 61.8 13.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG19781.1 - 1.1e-12 47.2 12.8 1.1e-12 47.2 8.9 3.8 3 2 1 4 4 4 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 EKG19782.1 - 1.6e-08 33.9 0.1 2.4e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG19782.1 - 0.017 13.9 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DUF2306 PF10067.4 EKG19783.1 - 7.8e-13 48.4 8.0 8.9e-13 48.2 4.3 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 EKG19783.1 - 1.1 9.2 6.7 8.1 6.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF420) PrgI PF12666.2 EKG19783.1 - 7.4 6.7 8.6 2.7 8.1 0.8 2.9 2 1 1 3 3 3 0 PrgI family protein adh_short PF00106.20 EKG19784.1 - 1.4e-15 57.5 2.9 6.1e-15 55.5 1.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19784.1 - 3e-09 36.7 0.5 5.6e-09 35.9 0.3 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG19784.1 - 0.00027 20.7 0.0 0.002 17.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ldh_1_N PF00056.18 EKG19784.1 - 0.006 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 EKG19784.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG19784.1 - 0.076 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EKG19784.1 - 0.11 12.5 1.3 0.41 10.6 0.9 2.0 1 1 0 1 1 1 0 NADH(P)-binding ThiF PF00899.16 EKG19784.1 - 0.52 10.1 3.1 7.1 6.4 2.2 2.3 1 1 0 1 1 1 0 ThiF family AMP-binding PF00501.23 EKG19785.1 - 3.5e-86 289.2 0.0 7e-86 288.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EKG19785.1 - 4e-68 229.6 0.0 1.2e-67 228.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EKG19785.1 - 2.1e-67 227.6 0.4 4.2e-67 226.7 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EKG19785.1 - 1.1e-59 201.1 1.2 1.1e-59 201.1 0.9 4.0 4 0 0 4 4 4 1 KR domain PS-DH PF14765.1 EKG19785.1 - 7.1e-55 186.2 0.5 1.3e-54 185.4 0.1 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 EKG19785.1 - 9.9e-52 175.2 7.2 5.8e-50 169.4 0.3 4.5 4 0 0 4 4 4 1 short chain dehydrogenase Condensation PF00668.15 EKG19785.1 - 1.7e-51 174.8 0.4 3.5e-51 173.8 0.3 1.5 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EKG19785.1 - 7e-37 125.8 1.3 2.2e-36 124.3 0.9 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EKG19785.1 - 9.7e-26 90.1 0.0 1.7e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EKG19785.1 - 9.5e-23 80.2 0.1 6e-12 45.6 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EKG19785.1 - 4.1e-22 78.1 0.0 1.6e-21 76.1 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG19785.1 - 1.3e-09 39.0 0.0 8.5e-09 36.3 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HxxPF_rpt PF13745.1 EKG19785.1 - 1.6e-07 31.5 0.0 1.7e-06 28.2 0.0 2.9 2 0 0 2 2 2 1 HxxPF-repeated domain ADH_N PF08240.7 EKG19785.1 - 0.0077 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EKG19785.1 - 0.035 13.0 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain AATase PF07247.7 EKG19785.1 - 3.9 5.8 0.0 8.6 4.7 0.0 1.5 1 1 0 1 1 1 0 Alcohol acetyltransferase HPP PF04982.8 EKG19788.1 - 1.6e-40 137.7 9.5 2.5e-40 137.0 5.8 1.7 2 0 0 2 2 2 1 HPP family EmrE PF13536.1 EKG19788.1 - 0.016 15.4 2.5 0.016 15.4 1.7 1.8 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Extensin_2 PF04554.8 EKG19791.1 - 1.5 8.7 6.7 0.32 10.8 1.6 1.9 2 0 0 2 2 2 0 Extensin-like region MFS_1 PF07690.11 EKG19792.1 - 1e-11 44.1 29.7 1.3e-11 43.8 20.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DAO PF01266.19 EKG19793.1 - 2.5e-23 82.5 0.4 3.4e-23 82.1 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG19793.1 - 1.7e-06 27.9 0.0 5.5e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG19793.1 - 0.00012 22.3 0.1 0.00075 19.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EKG19793.1 - 0.0018 18.5 0.0 0.0038 17.4 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 EKG19793.1 - 0.002 18.0 0.0 0.012 15.5 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG19793.1 - 0.0021 16.9 0.1 0.0058 15.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EKG19793.1 - 0.008 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EKG19793.1 - 0.049 12.5 0.1 0.08 11.7 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EKG19793.1 - 0.081 11.3 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_10 PF13460.1 EKG19793.1 - 0.14 12.1 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding Pyr_redox_3 PF13738.1 EKG19793.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG19793.1 - 0.16 11.0 0.1 0.72 8.9 0.0 2.0 2 1 1 3 3 3 0 Thi4 family ABC2_membrane PF01061.19 EKG19794.1 - 8.3e-34 116.5 14.9 1.3e-33 115.9 10.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EKG19794.1 - 6e-18 65.4 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.1 EKG19794.1 - 3.6e-17 62.2 0.0 7.5e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane PF01061.19 EKG19795.1 - 3.7e-44 150.3 15.6 3.7e-44 150.3 10.8 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 EKG19795.1 - 0.00028 20.5 1.6 0.00089 18.8 1.1 1.9 1 0 0 1 1 1 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EKG19795.1 - 0.0012 17.9 4.0 0.0012 17.9 2.7 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF3611 PF12263.3 EKG19795.1 - 0.79 9.0 6.2 0.22 10.8 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF3165 PF11364.3 EKG19795.1 - 1.2 9.3 8.7 2.4 8.3 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3165) AMP-binding PF00501.23 EKG19797.1 - 7.9e-20 70.6 0.0 1e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme COesterase PF00135.23 EKG19800.1 - 2.6e-10 39.6 0.0 3e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Pkinase PF00069.20 EKG19802.1 - 2.7e-30 105.3 0.0 4.1e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG19802.1 - 5.7e-08 32.1 0.0 1.2e-06 27.8 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase FAD_binding_4 PF01565.18 EKG19803.1 - 2.1e-20 72.6 1.1 4.5e-20 71.5 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG19803.1 - 1.1e-07 31.5 0.6 2.3e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF2959 PF11172.3 EKG19803.1 - 0.0016 18.2 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Cytokin-bind PF09265.5 EKG19803.1 - 0.14 11.3 0.4 0.21 10.6 0.3 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Fungal_trans_2 PF11951.3 EKG19805.1 - 6.3e-07 28.3 0.0 8e-07 27.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EKG19806.1 - 3.8e-39 134.4 8.2 5e-39 134.1 5.7 1.0 1 0 0 1 1 1 1 RTA1 like protein adh_short PF00106.20 EKG19808.1 - 6.9e-06 26.0 0.0 9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG19808.1 - 0.032 13.9 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase TRI9 PF08195.6 EKG19808.1 - 0.86 9.2 4.0 4.3 7.0 0.2 2.5 2 0 0 2 2 2 0 TRI9 protein Glyco_hydro_10 PF00331.15 EKG19809.1 - 1.8e-106 355.7 0.1 2.1e-106 355.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 BNR_2 PF13088.1 EKG19810.1 - 3.4e-19 69.1 5.1 2.3e-10 40.2 0.7 2.6 2 1 1 3 3 3 3 BNR repeat-like domain BNR PF02012.15 EKG19810.1 - 0.007 16.0 29.6 0.66 10.0 1.1 6.1 5 0 0 5 5 5 3 BNR/Asp-box repeat DUF3592 PF12158.3 EKG19810.1 - 0.047 13.4 0.5 0.18 11.5 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) Abhydrolase_6 PF12697.2 EKG19811.1 - 4.8e-28 98.6 5.5 6.4e-28 98.1 3.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG19811.1 - 1.1e-08 34.8 0.0 1.7e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG19811.1 - 2.9e-08 33.5 0.0 1.6e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3719 PF12516.3 EKG19811.1 - 0.0018 17.7 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3719) E1-E2_ATPase PF00122.15 EKG19812.1 - 3.2e-44 150.6 6.5 6.4e-44 149.6 4.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EKG19812.1 - 2.6e-28 99.9 0.0 4.5e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG19812.1 - 2.4e-12 47.4 0.0 5.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EKG19812.1 - 3e-05 24.0 0.0 0.00013 22.0 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EKG19812.1 - 0.00017 21.2 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glyco_hydro_72 PF03198.9 EKG19813.1 - 2e-133 444.2 5.9 2.4e-133 443.9 4.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Fungal_trans PF04082.13 EKG19814.1 - 0.0095 14.8 0.0 0.011 14.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EKG19816.1 - 3.1e-64 215.9 45.1 9.5e-35 119.6 12.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EKG19816.1 - 6.9e-28 96.3 0.2 2.9e-21 75.0 0.0 3.1 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EKG19816.1 - 6.3e-17 62.1 0.0 1e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EKG19816.1 - 7.1e-06 26.1 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKG19816.1 - 2.9e-05 23.5 0.0 0.00026 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EKG19816.1 - 0.00021 20.4 29.5 0.012 14.6 4.6 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EKG19816.1 - 0.00023 21.2 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EKG19816.1 - 0.0007 18.8 0.0 0.0016 17.6 0.0 1.6 2 0 0 2 2 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EKG19816.1 - 0.0009 18.7 0.2 0.0021 17.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EKG19816.1 - 0.0081 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EKG19816.1 - 0.017 14.5 0.2 0.027 13.9 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKG19816.1 - 0.028 14.5 0.1 0.072 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EKG19816.1 - 0.041 12.9 0.0 0.62 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EKG19816.1 - 0.051 13.2 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 EKG19816.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EKG19816.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EKG19816.1 - 0.24 11.0 0.1 0.42 10.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EKG19816.1 - 0.25 11.6 0.0 0.4 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKG19816.1 - 2.5 8.4 2.8 1.5 9.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Acyl_transf_3 PF01757.17 EKG19820.1 - 1.1e-30 106.7 36.2 2e-21 76.2 14.7 2.3 2 0 0 2 2 2 2 Acyltransferase family Rab5ip PF07019.7 EKG19820.1 - 0.013 15.5 1.3 0.076 13.1 0.1 2.6 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Abhydrolase_3 PF07859.8 EKG19821.1 - 4.6e-37 127.6 0.2 1.4e-36 126.0 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EKG19821.1 - 7.3e-06 24.8 0.0 0.029 12.9 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EKG19821.1 - 0.01 15.5 0.1 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cyt-b5 PF00173.23 EKG19822.1 - 1.3e-12 47.3 0.0 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SOG2 PF10428.4 EKG19823.1 - 0.027 13.1 9.7 0.033 12.8 6.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TMA7 PF09072.5 EKG19824.1 - 1.3e-11 44.7 21.6 3.7e-09 36.9 14.9 2.0 1 1 0 1 1 1 1 Translation machinery associated TMA7 PMSI1 PF15322.1 EKG19824.1 - 0.054 12.5 0.1 0.054 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ndc80_HEC PF03801.8 EKG19825.1 - 1.1e-54 184.2 0.2 2.5e-54 183.0 0.1 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Filament PF00038.16 EKG19825.1 - 0.038 13.4 51.8 0.061 12.7 12.6 3.5 2 1 1 3 3 3 0 Intermediate filament protein ApoO PF09769.4 EKG19825.1 - 2 8.0 6.9 0.4 10.3 0.3 2.9 2 1 1 3 3 3 0 Apolipoprotein O Lectin_N PF03954.9 EKG19825.1 - 3.4 7.0 8.1 0.47 9.8 0.4 3.1 2 1 2 4 4 4 0 Hepatic lectin, N-terminal domain Reo_sigmaC PF04582.7 EKG19825.1 - 5.6 6.0 7.3 3.2 6.8 0.9 2.7 2 2 1 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EKG19825.1 - 5.6 6.8 57.0 0.29 10.9 13.8 4.9 2 2 2 4 4 4 0 Tropomyosin like Seipin PF06775.9 EKG19826.1 - 0.0032 16.9 0.9 0.0045 16.5 0.6 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DPBB_1 PF03330.13 EKG19827.1 - 4.8e-06 26.4 0.3 1.1e-05 25.3 0.2 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Thioredoxin PF00085.15 EKG19827.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin F-box-like PF12937.2 EKG19828.1 - 0.00015 21.3 0.4 0.00015 21.3 0.3 2.3 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 EKG19828.1 - 0.017 14.7 0.2 0.04 13.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain RNA_POL_M_15KD PF02150.11 EKG19828.1 - 0.038 13.6 0.1 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Toxin_17 PF08086.6 EKG19828.1 - 0.13 12.3 0.9 0.24 11.4 0.2 1.8 2 0 0 2 2 2 0 Ergtoxin family OPT PF03169.10 EKG19829.1 - 4.3e-151 504.4 30.8 4.9e-151 504.2 21.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Amidohydro_4 PF13147.1 EKG19830.1 - 8.3e-13 48.9 13.7 2.3e-10 40.9 2.9 3.6 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EKG19830.1 - 2.7e-08 33.4 0.6 3.5e-07 29.9 0.2 2.8 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG19830.1 - 1.5e-07 31.3 0.2 3.3e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 EKG19830.1 - 0.00011 21.5 1.3 0.00025 20.4 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family HsbA PF12296.3 EKG19830.1 - 0.013 15.3 0.1 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 Hydrophobic surface binding protein A p450 PF00067.17 EKG19832.1 - 1.7e-54 185.1 0.0 2.3e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EzrA PF06160.7 EKG19833.1 - 0.0041 15.3 8.1 0.0077 14.4 5.6 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA T2SF PF00482.18 EKG19833.1 - 0.14 12.0 5.9 0.74 9.7 1.5 2.7 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F DUF812 PF05667.6 EKG19833.1 - 0.15 10.5 12.0 0.23 9.9 8.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF342 PF03961.8 EKG19833.1 - 0.84 7.9 3.3 1.2 7.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GvpL_GvpF PF06386.6 EKG19833.1 - 1.7 8.1 11.2 3.8 7.0 7.8 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF FlaC_arch PF05377.6 EKG19833.1 - 1.8 8.5 4.2 11 6.0 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 EKG19833.1 - 2.8 8.2 5.4 1.3 9.3 0.6 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.7 EKG19833.1 - 4.5 7.7 10.9 1.3 9.4 2.0 3.4 2 1 1 3 3 3 0 SlyX DUF2360 PF10152.4 EKG19833.1 - 8 6.7 11.4 20 5.4 0.7 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4414 PF14377.1 EKG19834.1 - 0.0075 16.1 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) AAA PF00004.24 EKG19835.1 - 8.3e-09 35.7 0.7 5e-05 23.4 0.0 2.6 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EKG19835.1 - 0.00047 20.0 0.0 0.002 17.9 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EKG19835.1 - 0.014 15.5 0.1 0.081 13.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 EKG19835.1 - 0.088 12.2 0.4 5.2 6.4 0.0 2.6 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EKG19835.1 - 0.11 12.4 0.1 0.29 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATP-grasp_4 PF13535.1 EKG19836.1 - 9.4e-05 22.2 0.1 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain GSH-S_ATP PF02955.11 EKG19836.1 - 0.0018 17.4 0.0 0.0027 16.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain RimK PF08443.6 EKG19836.1 - 0.0051 16.3 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain IBR PF01485.16 EKG19838.1 - 1e-14 54.1 41.8 1.6e-08 34.2 4.9 3.4 3 0 0 3 3 3 3 IBR domain zf-RING_2 PF13639.1 EKG19838.1 - 0.00042 20.0 10.3 0.00042 20.0 7.1 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKG19838.1 - 0.0052 16.7 11.4 0.0052 16.7 7.9 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.14 EKG19838.1 - 2.8 8.3 6.9 16 5.9 4.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein HET PF06985.6 EKG19839.1 - 7.9e-15 55.2 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF383 PF04063.9 EKG19842.1 - 3.6e-57 193.0 0.0 5.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EKG19842.1 - 7.4e-22 76.6 1.1 2.2e-21 75.1 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) BPL_N PF09825.4 EKG19843.1 - 3.6e-144 480.0 0.0 4.4e-144 479.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EKG19843.1 - 1.6e-17 63.6 0.0 4.3e-17 62.3 0.0 1.7 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family TTL PF03133.10 EKG19844.1 - 7.2e-55 185.9 0.0 1.5e-54 184.9 0.0 1.5 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EKG19844.1 - 0.00012 21.8 0.3 0.018 14.7 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EKG19844.1 - 0.0004 19.2 0.0 0.0064 15.3 0.0 2.5 3 0 0 3 3 3 1 YheC/D like ATP-grasp RNase_H2-Ydr279 PF09468.5 EKG19845.1 - 3.9e-91 305.4 0.1 5.7e-91 304.8 0.1 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) zf-primase PF09329.6 EKG19846.1 - 4e-18 64.7 0.7 6.8e-18 64.0 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger Glyco_hydro_32N PF00251.15 EKG19847.1 - 1.9e-68 231.0 0.2 2.3e-68 230.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EKG19847.1 - 7e-10 39.1 0.0 1.3e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EKG19847.1 - 0.063 13.1 0.5 1 9.4 0.0 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat BNR_2 PF13088.1 EKG19847.1 - 0.12 11.5 3.1 2.2 7.5 0.0 2.7 3 0 0 3 3 3 0 BNR repeat-like domain AflR PF08493.5 EKG19848.1 - 0.049 12.6 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein ADH_zinc_N PF00107.21 EKG19849.1 - 1.8e-16 59.8 0.0 2.8e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG19849.1 - 1.3e-05 26.0 0.0 2.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG19849.1 - 0.0042 16.8 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EKG19850.1 - 4.4e-24 85.7 1.4 5.2e-24 85.5 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EKG19850.1 - 1.3e-15 57.0 0.6 1.3e-15 57.0 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EKG19850.1 - 0.002 17.7 1.1 0.0032 17.0 0.7 1.4 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CbiG_N PF11760.3 EKG19850.1 - 0.1 12.3 0.6 0.22 11.2 0.4 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal DUF4110 PF13422.1 EKG19852.1 - 0.093 12.5 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) WD40 PF00400.27 EKG19854.1 - 1.2e-05 24.9 8.0 0.52 10.2 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat RINGv PF12906.2 EKG19855.1 - 1.4e-06 28.2 5.2 2.7e-06 27.3 3.6 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EKG19855.1 - 4.7e-05 23.2 2.6 8.5e-05 22.4 1.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EKG19855.1 - 7.9e-05 22.4 3.5 0.00013 21.6 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C4_Topoisom PF01396.14 EKG19855.1 - 0.078 12.4 0.8 0.14 11.6 0.5 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger zf-C3HC4_3 PF13920.1 EKG19855.1 - 0.1 12.2 2.4 0.17 11.5 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG19855.1 - 0.2 11.6 2.9 0.42 10.6 2.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4588 PF15251.1 EKG19855.1 - 1.4 8.7 8.6 0.03 14.3 1.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) DUF1691 PF07950.6 EKG19857.1 - 7.2e-38 128.8 5.3 5.7e-22 77.7 2.6 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1691) Sugar_tr PF00083.19 EKG19858.1 - 6.9e-112 374.2 22.6 8.1e-112 374.0 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG19858.1 - 7.9e-19 67.5 41.3 1.2e-14 53.7 11.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG19858.1 - 7.8e-08 30.9 10.5 8.5e-07 27.5 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) RFamide_26RFa PF11109.3 EKG19858.1 - 0.055 13.3 0.1 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 AAA_28 PF13521.1 EKG19859.1 - 5.1e-28 98.0 0.0 7.1e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG19859.1 - 0.016 15.4 0.0 0.044 14.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EKG19859.1 - 0.022 15.5 0.0 0.19 12.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG19859.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain RdRP PF05183.7 EKG19860.1 - 1.8e-131 439.6 0.0 2.8e-131 439.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase AAA_11 PF13086.1 EKG19860.1 - 9.7e-45 152.9 1.1 2.6e-43 148.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EKG19860.1 - 1e-42 145.8 0.0 1.7e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG19860.1 - 4.3e-14 52.0 1.2 1.1e-12 47.5 0.3 3.0 3 0 0 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EKG19860.1 - 5.4e-10 39.1 0.0 1.9e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EKG19860.1 - 1.1e-05 24.7 0.0 2.7e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 PhoH-like protein DEAD PF00270.24 EKG19860.1 - 3.2e-05 23.4 0.0 6.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EKG19860.1 - 0.00025 20.9 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EKG19860.1 - 0.00031 20.4 0.0 0.00073 19.2 0.0 1.6 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 EKG19860.1 - 0.0016 17.7 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EKG19860.1 - 0.0082 16.1 0.0 0.033 14.1 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EKG19860.1 - 0.011 15.9 0.0 0.048 13.8 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG19860.1 - 0.016 15.3 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EKG19860.1 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 EKG19860.1 - 0.048 13.0 0.0 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EKG19860.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Spore_YpjB PF09577.5 EKG19861.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Limkain-b1 PF11608.3 EKG19861.1 - 0.15 11.8 1.1 0.29 10.8 0.7 1.6 1 1 0 1 1 1 0 Limkain b1 IncA PF04156.9 EKG19862.1 - 3.3e-05 23.5 4.9 4.9e-05 22.9 3.4 1.3 1 0 0 1 1 1 1 IncA protein ATG16 PF08614.6 EKG19862.1 - 4.5e-05 23.3 7.9 7.1e-05 22.7 5.5 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) 7TMR-HDED PF07697.6 EKG19862.1 - 0.0088 15.7 4.4 0.012 15.3 3.1 1.3 1 0 0 1 1 1 1 7TM-HD extracellular Mnd1 PF03962.10 EKG19862.1 - 0.013 15.2 7.6 0.02 14.5 5.3 1.4 1 0 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 EKG19862.1 - 0.031 12.7 6.3 0.038 12.4 4.4 1.2 1 0 0 1 1 1 0 AAA domain Phlebovirus_NSM PF07246.6 EKG19862.1 - 0.042 13.0 6.5 0.06 12.4 4.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Med8 PF10232.4 EKG19862.1 - 0.062 12.8 3.3 0.087 12.3 2.3 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 V_ATPase_I PF01496.14 EKG19862.1 - 0.083 10.7 3.1 0.089 10.6 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol3_alpha PF07733.7 EKG19862.1 - 0.096 11.0 2.7 0.13 10.6 0.0 2.0 1 1 1 2 2 2 0 Bacterial DNA polymerase III alpha subunit DUF4200 PF13863.1 EKG19862.1 - 0.12 12.3 17.4 0.12 12.3 10.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF724 PF05266.9 EKG19862.1 - 0.17 11.5 6.7 0.27 10.8 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Paralemmin PF03285.10 EKG19862.1 - 0.45 9.9 8.4 1.8 7.9 6.0 1.8 1 1 1 2 2 2 0 Paralemmin DUF342 PF03961.8 EKG19862.1 - 0.49 8.7 5.6 0.59 8.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EKG19862.1 - 0.55 9.2 7.7 0.7 8.8 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 EKG19862.1 - 0.61 9.5 4.4 1.1 8.6 3.1 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 EKG19862.1 - 1 8.2 11.5 1.5 7.6 8.0 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4140 PF13600.1 EKG19862.1 - 1.2 9.6 11.4 1.5 9.2 6.1 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DMPK_coil PF08826.5 EKG19862.1 - 1.3 8.9 13.9 1.2 9.1 5.6 3.0 2 1 1 3 3 3 0 DMPK coiled coil domain like DivIC PF04977.10 EKG19862.1 - 6.5 6.3 13.4 11 5.6 8.1 2.3 2 1 1 3 3 3 0 Septum formation initiator Aldo_ket_red PF00248.16 EKG19864.1 - 2.4e-32 111.9 0.0 2.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EKG19865.1 - 1.7e-10 40.2 0.0 2e-10 39.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1493 PF07377.7 EKG19865.1 - 0.09 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) DIOX_N PF14226.1 EKG19866.1 - 3.3e-07 30.8 0.0 4.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal HMG_box PF00505.14 EKG19868.1 - 2.3e-26 91.8 1.7 3.7e-26 91.1 1.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKG19868.1 - 5.4e-21 74.7 1.8 8.5e-21 74.1 1.2 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EKG19868.1 - 0.00097 18.8 0.4 0.00097 18.8 0.3 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box 5 Btz PF09405.5 EKG19868.1 - 0.82 9.7 6.0 1.1 9.3 3.7 1.6 1 1 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding HMG_CoA_synt_C PF08540.5 EKG19869.1 - 6.5e-106 353.9 0.2 8.8e-106 353.4 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EKG19869.1 - 4.8e-96 319.2 0.2 7.6e-96 318.6 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3541 PF12060.3 EKG19869.1 - 0.079 12.2 0.2 0.22 10.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) DUF4190 PF13828.1 EKG19871.1 - 0.045 13.2 3.7 0.098 12.2 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) SUKH_5 PF14567.1 EKG19872.1 - 0.081 12.3 0.2 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall zf-RanBP PF00641.13 EKG19872.1 - 0.2 10.7 0.3 0.2 10.7 0.2 1.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Tannase PF07519.6 EKG19873.1 - 1.4e-95 320.7 0.6 1.7e-95 320.5 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EKG19873.1 - 2.7e-08 33.9 0.0 1.2e-07 31.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG19873.1 - 4.5e-05 22.7 0.0 0.24 10.5 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG19873.1 - 0.00013 21.7 0.1 0.024 14.3 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG19873.1 - 0.0099 15.4 0.1 0.019 14.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 EKG19876.1 - 0.00023 19.9 0.3 0.00028 19.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_2 PF07719.12 EKG19876.1 - 4.3 7.5 5.1 1.2 9.1 1.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat HATPase_c PF02518.21 EKG19877.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MSA-2c PF12238.3 EKG19877.1 - 1.1 8.8 4.6 1.7 8.2 3.2 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Fungal_trans PF04082.13 EKG19878.1 - 8e-12 44.5 0.0 1.5e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aconitase PF00330.15 EKG19879.1 - 5.5e-157 522.9 0.0 6.8e-157 522.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EKG19879.1 - 5.7e-36 123.5 0.0 1e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MFS_1 PF07690.11 EKG19881.1 - 2.3e-18 66.0 44.9 2.3e-18 66.0 31.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG19881.1 - 0.088 11.1 34.8 0.041 12.2 12.1 2.5 1 1 1 2 2 2 0 MFS/sugar transport protein DIOX_N PF14226.1 EKG19882.1 - 8.3e-21 74.6 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG19882.1 - 9e-12 45.1 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HMGL-like PF00682.14 EKG19883.1 - 3.4e-54 184.0 0.0 5.2e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 HMGL-like BLIP PF07467.6 EKG19883.1 - 0.03 13.9 0.6 0.084 12.5 0.0 1.9 2 0 0 2 2 2 0 Beta-lactamase inhibitor (BLIP) bZIP_1 PF00170.16 EKG19885.1 - 1.2e-07 31.5 8.4 1.1e-06 28.4 5.8 2.2 1 1 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EKG19885.1 - 0.0099 15.4 0.6 0.021 14.4 0.4 1.4 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain FdhE PF04216.7 EKG19885.1 - 0.013 15.2 5.5 0.016 14.9 3.8 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation HALZ PF02183.13 EKG19885.1 - 0.022 14.4 0.2 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_2 PF07716.10 EKG19885.1 - 0.028 14.2 9.9 1.3 8.9 6.9 2.5 1 1 0 1 1 1 0 Basic region leucine zipper SSV1_ORF_D-335 PF07935.6 EKG19885.1 - 0.061 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 ORF D-335-like protein dsrm PF00035.20 EKG19885.1 - 0.69 10.5 0.1 0.69 10.5 0.1 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif Adeno_PIX PF03955.9 EKG19885.1 - 0.86 10.1 9.9 0.33 11.4 0.7 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) MS_channel PF00924.13 EKG19886.1 - 3.5e-18 65.7 1.7 4e-18 65.5 0.4 1.6 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EKG19886.1 - 0.00029 19.9 0.1 0.00029 19.9 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EKG19886.1 - 0.0026 17.4 0.1 0.0092 15.7 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 EKG19886.1 - 0.0038 16.5 0.2 0.011 15.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EKG19886.1 - 0.0089 16.1 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF1189 PF06691.6 EKG19886.1 - 0.29 10.4 6.5 0.018 14.3 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) DUF2458 PF10454.4 EKG19888.1 - 1.5e-26 93.0 0.8 1.6e-12 47.5 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2458) DUF1543 PF07566.7 EKG19889.1 - 1.5 8.3 4.2 8.9 5.9 0.1 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1543) zf-AN1 PF01428.11 EKG19890.1 - 0.012 15.4 1.2 0.012 15.4 0.9 1.6 2 0 0 2 2 2 0 AN1-like Zinc finger 7tm_7 PF08395.7 EKG19892.1 - 0.0018 17.3 1.7 0.0026 16.8 1.2 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor Claudin_3 PF06653.6 EKG19892.1 - 0.011 15.4 3.1 0.018 14.7 2.2 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like NicO PF03824.11 EKG19892.1 - 0.017 14.4 0.5 0.025 13.9 0.4 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF4231 PF14015.1 EKG19892.1 - 0.11 12.4 1.3 0.25 11.3 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) PGG PF13962.1 EKG19892.1 - 1.7 8.2 4.6 2.9 7.5 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function Arf PF00025.16 EKG19893.1 - 4.7e-73 244.1 0.0 5.2e-73 243.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKG19893.1 - 2.7e-13 49.5 0.0 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EKG19893.1 - 1.4e-11 44.0 0.0 1.6e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EKG19893.1 - 1e-10 40.9 0.5 7.2e-07 28.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EKG19893.1 - 1.2e-09 37.7 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EKG19893.1 - 1.8e-07 31.6 0.0 2.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKG19893.1 - 6.1e-06 26.1 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG19893.1 - 1.3e-05 24.7 0.0 0.0018 17.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EKG19893.1 - 0.02 14.1 0.5 0.079 12.2 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 EKG19893.1 - 0.06 13.8 0.2 0.16 12.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Amidase PF01425.16 EKG19894.1 - 9.8e-78 261.9 0.0 1.3e-77 261.5 0.0 1.2 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EKG19894.1 - 2.9e-33 115.2 0.0 1.3e-32 113.1 0.0 2.0 2 0 0 2 2 2 1 Isochorismatase family DUF550 PF04447.7 EKG19894.1 - 0.15 11.6 1.1 0.38 10.3 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF550) Actin PF00022.14 EKG19895.1 - 1.1e-27 96.5 0.0 5.2e-26 90.9 0.0 2.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKG19895.1 - 0.0079 14.8 0.0 0.51 8.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Paf1 PF03985.8 EKG19896.1 - 1.7e-18 66.6 0.0 1.8e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Paf1 Paf1 PF03985.8 EKG19897.1 - 2e-10 40.0 0.3 0.00013 20.8 0.1 2.1 2 0 0 2 2 2 2 Paf1 GH-E PF14410.1 EKG19897.1 - 0.0093 16.0 0.1 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 HNH/ENDO VII superfamily nuclease with conserved GHE residues ADH_N PF08240.7 EKG19898.1 - 1.5e-14 53.6 0.0 3.8e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG19898.1 - 3e-09 36.5 0.1 1.1e-07 31.4 0.1 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EKG19898.1 - 0.013 13.9 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EKG19898.1 - 0.068 13.5 0.5 0.72 10.2 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG19898.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Dispanin PF04505.7 EKG19899.1 - 0.039 13.4 0.1 0.066 12.7 0.1 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein p450 PF00067.17 EKG19901.1 - 6.9e-62 209.4 0.0 8.3e-62 209.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG19902.1 - 1e-27 96.7 0.0 1.4e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EKG19903.1 - 2.3e-106 356.0 18.1 2.7e-106 355.8 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG19903.1 - 1.8e-20 72.9 25.9 1.8e-20 72.9 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP_assoc PF03828.14 EKG19904.1 - 1.1e-15 57.3 0.0 2.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EKG19904.1 - 9.3e-06 25.8 0.0 2.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EKG19904.1 - 0.00032 19.6 0.0 0.026 13.3 0.0 2.5 3 0 0 3 3 3 2 Poly(A) polymerase central domain SpoU_sub_bind PF08032.7 EKG19904.1 - 0.18 12.0 0.0 0.9 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Nrap PF03813.9 EKG19904.1 - 0.35 8.3 0.0 0.84 7.0 0.0 1.5 2 0 0 2 2 2 0 Nrap protein NAD_binding_10 PF13460.1 EKG19906.1 - 1.9e-06 27.9 0.4 3.9e-06 27.0 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EKG19906.1 - 2.4e-05 23.7 0.0 4.9e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EKG19907.1 - 5e-15 55.8 0.1 7.7e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19907.1 - 2.1e-06 27.4 0.2 3.3e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.17 EKG19908.1 - 1.7e-46 158.6 0.3 2.1e-46 158.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG19910.1 - 2.2e-27 95.9 0.4 2.9e-27 95.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG19910.1 - 2e-18 67.0 0.0 2.6e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG19910.1 - 1.5e-10 41.0 0.1 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EKG19910.1 - 0.0025 17.6 0.4 0.004 16.9 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain MTS PF05175.9 EKG19910.1 - 0.12 11.7 0.6 0.4 10.0 0.2 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Ribosomal_L18e PF00828.14 EKG19911.1 - 9.9e-34 116.4 0.1 1.4e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Fe-S_biosyn PF01521.15 EKG19912.1 - 3.1e-12 46.3 0.0 3.4e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Aminotran_5 PF00266.14 EKG19913.1 - 1.2e-13 50.5 0.0 2.5e-13 49.5 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V NST1 PF13945.1 EKG19914.1 - 2.6e-63 213.5 0.0 2.6e-63 213.5 0.0 5.0 3 1 2 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 EKG19915.1 - 6.2e-48 162.2 0.0 7.3e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG19915.1 - 1.9e-16 60.6 0.0 2.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG19915.1 - 4.7e-08 32.4 0.0 6.4e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG19915.1 - 0.0095 15.1 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EKG19915.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EKG19915.1 - 0.045 13.2 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EKG19915.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EKG19915.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 EKG19916.1 - 3.9e-08 33.2 1.2 2e-07 30.9 0.8 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L28 Glyco_transf_4 PF13439.1 EKG19916.1 - 0.068 12.8 0.3 0.096 12.4 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 PGM_PMM_I PF02878.11 EKG19917.1 - 1.3e-18 66.7 0.4 1.8e-08 33.9 0.0 3.2 2 1 2 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EKG19917.1 - 2.1e-14 53.7 0.1 8.7e-14 51.7 0.1 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EKG19917.1 - 6.2e-11 42.1 0.7 1.9e-10 40.6 0.5 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EKG19917.1 - 0.0033 17.4 0.1 0.0092 16.0 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Inositol_P PF00459.20 EKG19918.1 - 9e-69 231.7 0.0 1e-68 231.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family adh_short PF00106.20 EKG19919.1 - 7.9e-05 22.6 0.6 0.089 12.7 0.2 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Saccharop_dh PF03435.13 EKG19920.1 - 3.9e-09 35.9 0.1 4.9e-07 29.0 0.1 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EKG19920.1 - 7.1e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF3833 PF12915.2 EKG19920.1 - 0.0034 16.6 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3833) Epimerase PF01370.16 EKG19920.1 - 0.0037 16.7 0.0 0.019 14.4 0.0 2.1 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family MIP PF00230.15 EKG19924.1 - 1e-55 188.6 5.8 1.3e-55 188.3 4.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 EKG19925.1 - 3e-73 245.6 0.8 4.5e-73 245.0 0.6 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EKG19925.1 - 1.9e-66 223.8 0.0 2.5e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain AT_hook PF02178.14 EKG19926.1 - 0.032 13.8 3.1 0.032 13.8 2.2 3.4 2 0 0 2 2 2 0 AT hook motif DUF3433 PF11915.3 EKG19927.1 - 1.2e-50 169.6 7.3 7e-28 96.6 1.4 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) CopD PF05425.8 EKG19927.1 - 0.093 12.9 1.7 0.33 11.1 0.2 2.7 3 0 0 3 3 3 0 Copper resistance protein D DUF4381 PF14316.1 EKG19927.1 - 0.74 9.9 6.5 0.12 12.5 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) TRI12 PF06609.8 EKG19928.1 - 8.1e-65 219.1 22.3 1e-64 218.7 15.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG19928.1 - 3.9e-28 98.1 37.8 3.9e-28 98.1 26.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG19928.1 - 7.1e-09 34.7 15.6 7.1e-09 34.7 10.8 3.7 4 1 0 4 4 4 1 Sugar (and other) transporter CorA PF01544.13 EKG19929.1 - 3.6e-07 29.5 0.9 1.7e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Viral_env_E26 PF11050.3 EKG19929.1 - 0.049 12.8 0.3 0.1 11.7 0.2 1.4 1 0 0 1 1 1 0 Virus envelope protein E26 Na_H_Exchanger PF00999.16 EKG19929.1 - 0.21 10.0 0.1 0.32 9.4 0.1 1.2 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Methyltransf_2 PF00891.13 EKG19930.1 - 6e-33 114.0 0.0 7.7e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EKG19930.1 - 3.4e-05 23.6 0.0 6.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG19930.1 - 0.0022 18.5 0.0 0.0084 16.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG19930.1 - 0.0064 16.9 0.0 0.033 14.6 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EKG19930.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 EKG19930.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain GMC_oxred_N PF00732.14 EKG19931.1 - 1.6e-49 168.6 0.0 2.1e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG19931.1 - 6.8e-09 35.0 0.3 1.9e-08 33.5 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG19931.1 - 4.1e-07 29.2 0.8 5.3e-05 22.2 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EKG19931.1 - 0.00037 20.6 0.0 0.064 13.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG19931.1 - 0.00067 18.6 0.2 0.0011 17.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG19931.1 - 0.0012 18.8 3.2 0.0019 18.1 0.3 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG19931.1 - 0.0058 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG19931.1 - 0.016 14.3 0.2 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EKG19931.1 - 0.017 13.6 0.2 0.025 13.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EKG19931.1 - 0.073 12.8 0.4 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EKG19931.1 - 0.095 11.3 0.2 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase SR-25 PF10500.4 EKG19932.1 - 0.16 11.3 9.2 0.22 10.9 6.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DIOX_N PF14226.1 EKG19933.1 - 1.4e-32 112.6 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG19933.1 - 1.4e-21 76.5 0.0 4e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EKG19934.1 - 3e-57 194.1 0.0 3.4e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EKG19935.1 - 6.5e-41 140.2 54.3 6.5e-41 140.2 37.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG19935.1 - 5.1e-11 41.4 19.3 8.1e-11 40.8 13.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG19935.1 - 3.4e-07 29.2 41.1 3e-05 22.7 11.3 3.3 2 2 1 3 3 3 2 Sugar (and other) transporter adh_short PF00106.20 EKG19936.1 - 7.3e-17 61.7 0.2 1.1e-16 61.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19936.1 - 8.5e-09 35.3 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG19936.1 - 0.0013 18.7 0.1 0.0031 17.5 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EKG19936.1 - 0.0013 18.5 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_S9 PF00326.16 EKG19937.1 - 7.7e-21 74.2 0.0 6.7e-14 51.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EKG19937.1 - 3.5e-16 59.4 0.0 1.4e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG19937.1 - 6.2e-12 45.4 0.0 1.5e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG19937.1 - 2.2e-10 40.8 0.1 3.1e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG19937.1 - 5.8e-09 35.7 0.0 0.002 17.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 EKG19937.1 - 5.9e-07 28.9 0.0 0.00066 19.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.7 EKG19937.1 - 0.0094 14.4 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DUF829 PF05705.9 EKG19937.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) LIP PF03583.9 EKG19937.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Secretory lipase FSH1 PF03959.8 EKG19937.1 - 0.087 12.2 0.0 2 7.8 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.8 EKG19937.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein ketoacyl-synt PF00109.21 EKG19938.1 - 3.9e-78 262.4 1.1 3.9e-78 262.4 0.7 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG19938.1 - 7.8e-38 128.9 1.1 4.1e-37 126.6 0.2 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EKG19938.1 - 3.2e-23 82.5 0.4 3.8e-22 79.0 0.1 2.2 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.7 EKG19938.1 - 4.5e-14 52.7 0.0 1.1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EKG19938.1 - 6.5e-10 39.1 0.2 1.6e-09 37.8 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EKG19938.1 - 1.9e-08 34.2 0.0 2.2e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG19938.1 - 3.6e-05 24.1 0.0 0.00012 22.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EKG19938.1 - 0.0022 17.0 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EKG19938.1 - 0.044 12.8 0.0 0.094 11.8 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AMP-binding PF00501.23 EKG19939.1 - 1.5e-36 125.7 0.0 4.6e-36 124.1 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EKG19939.1 - 7.1e-28 97.1 0.0 1.1e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EKG19939.1 - 6.8e-06 25.6 0.4 3.5e-05 23.3 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EKG19939.1 - 8.1e-06 25.8 0.3 2e-05 24.5 0.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG19939.1 - 0.00068 19.3 0.1 0.0016 18.1 0.1 1.7 1 0 0 1 1 1 1 KR domain PP-binding PF00550.20 EKG19939.1 - 0.0011 19.1 0.1 0.0043 17.2 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EKG19939.1 - 0.019 13.8 0.1 0.71 8.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EKG19939.1 - 0.026 13.4 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EKG19939.1 - 0.18 11.7 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EKG19939.1 - 0.21 10.2 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EKG19940.1 - 3.2e-05 23.9 0.1 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG19940.1 - 5.4e-05 23.0 0.1 0.00015 21.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Auxin_BP PF02041.11 EKG19940.1 - 0.061 12.7 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Pyr_redox_3 PF13738.1 EKG19941.1 - 4.6e-05 23.5 0.0 5.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG19941.1 - 0.0005 18.3 0.0 0.00057 18.2 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EKG19941.1 - 0.0061 15.5 0.0 0.0062 15.5 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) MFS_1 PF07690.11 EKG19942.1 - 1.9e-34 118.9 55.7 1.4e-27 96.3 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4106 PF13388.1 EKG19942.1 - 0.099 11.5 4.0 0.14 11.0 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Methyltransf_23 PF13489.1 EKG19943.1 - 7.8e-21 74.4 0.0 1.2e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG19943.1 - 7e-11 42.4 0.0 1.5e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG19943.1 - 3.8e-09 37.1 0.0 3.1e-08 34.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG19943.1 - 3.9e-08 33.0 0.0 3.2e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG19943.1 - 4.6e-07 29.1 0.0 6.7e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EKG19943.1 - 1.2e-06 28.8 0.0 5.7e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG19943.1 - 4.8e-06 26.8 0.0 1.6e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG19943.1 - 3.2e-05 23.9 0.0 6.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG19943.1 - 0.004 16.3 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EKG19943.1 - 0.0068 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EKG19943.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 EKG19943.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EKG19943.1 - 0.039 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EKG19943.1 - 0.084 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Porin_4 PF13609.1 EKG19944.1 - 0.027 13.9 2.0 0.065 12.7 0.6 1.9 1 1 1 2 2 2 0 Gram-negative porin Abhydrolase_6 PF12697.2 EKG19945.1 - 1.7e-31 109.9 2.5 3.1e-31 109.0 1.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG19945.1 - 4.9e-17 62.2 0.2 4.9e-14 52.4 0.4 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG19945.1 - 2.9e-12 46.5 0.0 1e-11 44.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG19945.1 - 0.0022 17.7 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase AXE1 PF05448.7 EKG19945.1 - 0.055 11.9 0.0 0.08 11.4 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) FAD_binding_3 PF01494.14 EKG19946.1 - 1.3e-10 40.9 0.8 8.7e-09 34.8 0.3 2.6 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EKG19946.1 - 3.1e-08 33.4 0.8 7.7e-08 32.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG19946.1 - 1.9e-07 30.3 6.9 2.1e-05 23.6 0.9 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG19946.1 - 5.3e-06 26.4 0.8 8.7e-06 25.7 0.6 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG19946.1 - 1.4e-05 24.1 1.7 2.9e-05 23.0 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EKG19946.1 - 0.00014 22.2 1.5 0.0002 21.6 0.5 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG19946.1 - 0.00027 20.1 0.1 0.00053 19.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EKG19946.1 - 0.00056 18.8 0.4 0.00076 18.4 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EKG19946.1 - 0.00082 17.9 0.4 0.00082 17.9 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 EKG19946.1 - 0.0014 17.3 0.4 0.0025 16.5 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EKG19946.1 - 0.0024 16.8 1.8 0.029 13.3 1.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EKG19946.1 - 0.0028 16.8 0.7 0.0037 16.4 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EKG19946.1 - 0.003 17.6 0.3 0.0049 16.9 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EKG19946.1 - 0.012 15.1 0.5 0.034 13.7 0.4 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EKG19946.1 - 0.017 14.5 0.5 0.031 13.7 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EKG19946.1 - 0.017 14.8 3.0 0.31 10.8 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EKG19946.1 - 0.041 13.6 0.1 0.071 12.8 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 EKG19946.1 - 0.21 10.5 2.1 0.39 9.7 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.13 EKG19949.1 - 3.9e-08 32.4 0.8 5e-05 22.2 0.2 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Acyl-CoA_dh_1 PF00441.19 EKG19950.1 - 4.5e-33 114.4 3.4 4.5e-33 114.4 2.4 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG19950.1 - 5.2e-18 65.6 0.1 1.4e-17 64.2 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EKG19950.1 - 5.4e-15 55.8 7.3 1.5e-14 54.3 2.9 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EKG19950.1 - 9e-14 50.7 0.1 2.4e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Fungal_trans PF04082.13 EKG19951.1 - 8.7e-25 87.0 0.1 1.5e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ArgJ PF01960.13 EKG19953.1 - 2.3e-10 39.4 0.0 2.8e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Pectinesterase PF01095.14 EKG19954.1 - 9.8e-26 90.0 0.3 4.7e-22 77.9 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase GST_N_2 PF13409.1 EKG19955.1 - 5.5e-07 29.4 0.1 1.6e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG19955.1 - 6.6e-07 29.1 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EKG19955.1 - 1.5e-06 28.2 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EKG19955.1 - 8.5e-05 22.4 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EKG19955.1 - 0.024 15.0 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain BNR_2 PF13088.1 EKG19956.1 - 0.00041 19.7 0.1 0.035 13.4 0.0 2.2 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EKG19956.1 - 0.00054 19.3 3.8 0.32 10.9 0.1 3.5 3 0 0 3 3 3 2 BNR/Asp-box repeat Glyco_hydro_43 PF04616.9 EKG19956.1 - 0.015 14.3 0.3 0.047 12.7 0.0 1.8 2 1 0 2 2 2 0 Glycosyl hydrolases family 43 SNF2_N PF00176.18 EKG19957.1 - 1.1e-70 237.8 0.0 1.9e-70 237.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG19957.1 - 3.6e-16 58.7 0.1 2.1e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DivIC PF04977.10 EKG19957.1 - 0.034 13.6 0.5 0.15 11.5 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Pex14_N PF04695.8 EKG19958.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phage_holin_6 PF10746.4 EKG19959.1 - 0.011 15.3 1.3 0.79 9.4 0.0 2.7 2 0 0 2 2 2 0 Phage holin family 6 Neisseria_TspB PF05616.8 EKG19960.1 - 1.7 6.9 6.0 1.9 6.7 4.2 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ADH_N PF08240.7 EKG19961.1 - 1.1e-25 89.5 4.7 1.8e-25 88.7 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG19961.1 - 1.3e-19 70.0 0.1 2.4e-19 69.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG19961.1 - 0.0055 17.5 0.3 1.1 10.1 0.2 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG19961.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EKG19961.1 - 0.073 13.0 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding ELFV_dehydrog PF00208.16 EKG19961.1 - 0.12 11.9 0.1 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TATR PF03430.8 EKG19962.1 - 8.1 4.9 6.9 7.6 5.0 4.8 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Mem_trans PF03547.13 EKG19962.1 - 9.2 4.4 5.9 8.4 4.5 4.1 1.1 1 0 0 1 1 1 0 Membrane transport protein HET PF06985.6 EKG19963.1 - 1.1e-22 80.6 0.0 2.5e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 EKG19964.1 - 1.2e-09 37.7 0.0 0.002 17.8 0.0 3.0 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 EKG19964.1 - 3.6e-09 36.0 0.0 0.0032 17.0 0.0 2.5 1 1 1 2 2 2 2 F-box domain PRANC PF09372.5 EKG19964.1 - 0.1 12.6 0.0 4.8 7.2 0.0 2.3 1 1 1 2 2 2 0 PRANC domain Longin PF13774.1 EKG19965.1 - 2.7e-16 58.8 0.0 4.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EKG19965.1 - 9.9e-14 50.7 0.1 1.6e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EKG19965.1 - 0.0072 16.0 0.4 0.017 14.8 0.3 1.6 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Sec63 PF02889.11 EKG19966.1 - 2.9e-151 503.0 0.0 3.7e-96 322.0 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EKG19966.1 - 9.6e-54 181.3 0.0 8.9e-29 100.1 0.3 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG19966.1 - 2.7e-17 62.3 0.0 2.7e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EKG19966.1 - 4.3e-15 56.0 0.0 1.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EKG19966.1 - 3.7e-08 33.5 0.1 0.022 14.9 0.0 3.5 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EKG19966.1 - 1.3e-05 24.8 0.0 0.023 14.4 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 EKG19966.1 - 4.8e-05 23.5 0.3 6.7 6.9 0.0 4.4 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 EKG19966.1 - 8.3e-05 21.5 0.2 0.36 9.5 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 EKG19966.1 - 0.0048 16.3 0.1 11 5.3 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein Methyltransf_25 PF13649.1 EKG19966.1 - 0.064 13.6 0.0 0.31 11.4 0.0 2.2 1 0 0 1 1 1 0 Methyltransferase domain Zeta_toxin PF06414.7 EKG19966.1 - 0.086 11.9 0.0 34 3.4 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin MFS_1 PF07690.11 EKG19967.1 - 1.9e-37 128.8 23.9 2.8e-37 128.2 15.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.8 EKG19968.1 - 5.5e-79 265.6 0.1 6.7e-79 265.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DAHP_synth_1 PF00793.15 EKG19970.1 - 1.9e-79 266.2 0.0 2.1e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Asp PF00026.18 EKG19970.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic aspartyl protease Sulfate_transp PF00916.15 EKG19971.1 - 5.9e-77 258.4 9.0 9.2e-77 257.7 6.2 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EKG19971.1 - 2e-22 78.6 1.1 2e-22 78.6 0.8 4.0 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EKG19971.1 - 1.7e-07 30.6 0.0 3.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain Fungal_lectin PF07938.7 EKG19972.1 - 1.4e-07 31.1 0.8 1.4e-07 31.1 0.5 2.8 2 1 1 3 3 3 1 Fungal fucose-specific lectin RskA PF10099.4 EKG19972.1 - 0.067 12.9 0.5 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DIOX_N PF14226.1 EKG19974.1 - 1.4e-10 41.6 0.0 2.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Sulfatase PF00884.18 EKG19975.1 - 8.6e-48 163.0 0.0 1.3e-45 155.9 0.0 2.3 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EKG19975.1 - 1.9e-05 24.1 0.0 9.7e-05 21.8 0.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EKG19975.1 - 0.0039 17.4 0.0 0.0069 16.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase FAD_binding_4 PF01565.18 EKG19976.1 - 2.8e-19 68.9 0.6 3.7e-19 68.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain Terpene_synth_C PF03936.11 EKG19978.1 - 1.4e-10 40.8 0.0 2.3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain YesK PF14150.1 EKG19979.1 - 0.053 13.6 1.0 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 YesK-like protein DUF202 PF02656.10 EKG19979.1 - 1 9.6 4.8 0.62 10.3 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Cuticle_1 PF08140.6 EKG19981.1 - 0.2 11.4 1.1 13 5.6 0.0 3.1 2 1 1 3 3 3 0 Crustacean cuticle protein repeat Me-amine-dh_L PF02975.9 EKG19982.1 - 0.031 14.2 1.4 0.047 13.6 1.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain p450 PF00067.17 EKG19983.1 - 6.5e-26 90.8 0.0 1.4e-25 89.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF4078 PF13300.1 EKG19984.1 - 3.1e-26 91.3 20.4 3.1e-26 91.3 14.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Alph_Pro_TM PF09608.5 EKG19984.1 - 0.37 10.2 6.9 0.029 13.8 0.3 2.3 2 1 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) DUF1943 PF09172.6 EKG19984.1 - 1.5 7.6 5.3 1.2 7.9 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Homoserine_dh PF00742.14 EKG19985.1 - 9.2e-52 175.2 0.0 1.2e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EKG19985.1 - 3.2e-11 43.6 0.0 5.9e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OMP_b-brl_3 PF14905.1 EKG19986.1 - 0.061 12.0 1.4 0.078 11.6 1.0 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family Mito_carr PF00153.22 EKG19987.1 - 9e-59 195.2 2.2 8.3e-21 73.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_71 PF03659.9 EKG19988.1 - 1.4e-54 185.0 0.6 1.6e-54 184.9 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 MAP65_ASE1 PF03999.7 EKG19990.1 - 2.3 6.7 6.4 2.9 6.3 4.4 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) dCMP_cyt_deam_1 PF00383.17 EKG19992.1 - 3e-25 87.8 0.0 3.9e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EKG19992.1 - 0.0091 15.8 0.5 0.072 12.9 0.3 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase COX16 PF14138.1 EKG19993.1 - 2.5e-34 117.2 0.1 2.9e-34 117.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 PI3_PI4_kinase PF00454.22 EKG19994.1 - 9.7e-49 165.9 0.0 1.7e-48 165.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EKG19994.1 - 2.9e-40 138.3 6.7 1.4e-39 136.1 1.5 2.9 3 0 0 3 3 3 1 FAT domain UME PF08064.8 EKG19994.1 - 2.2e-29 101.5 0.0 1.5e-28 98.8 0.0 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EKG19994.1 - 6.4e-13 47.8 0.0 1.8e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 FATC domain TPR_19 PF14559.1 EKG19994.1 - 8.4e-06 26.0 0.0 0.00013 22.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKG19994.1 - 0.094 12.3 4.5 0.73 9.5 0.1 4.1 5 0 0 5 5 5 0 TPR repeat Pro-kuma_activ PF09286.6 EKG19995.1 - 1.1e-28 100.0 0.0 2.1e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Asp PF00026.18 EKG19996.1 - 6.4e-08 32.1 0.0 8.2e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Amidohydro_4 PF13147.1 EKG19997.1 - 3.2e-24 86.4 0.0 1.9e-22 80.5 0.0 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG19997.1 - 5.3e-21 75.6 0.6 5e-09 36.2 0.0 2.9 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EKG19997.1 - 4.2e-10 39.3 0.3 1.5e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG19997.1 - 5.9e-10 38.9 1.1 4.7e-06 26.0 0.0 3.1 2 1 1 3 3 3 2 Amidohydrolase family TatD_DNase PF01026.16 EKG19997.1 - 0.028 13.6 0.0 0.054 12.6 0.0 1.7 1 1 0 1 1 1 0 TatD related DNase DUF2235 PF09994.4 EKG19998.1 - 8.5e-72 241.8 0.0 1.4e-71 241.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DAO PF01266.19 EKG20001.1 - 1.4e-39 136.0 0.2 2.1e-39 135.4 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG20001.1 - 6.5e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG20001.1 - 3e-05 24.0 0.0 0.043 13.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG20001.1 - 0.00065 19.4 0.0 0.051 13.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG20001.1 - 0.029 14.4 0.0 0.32 11.0 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG20001.1 - 0.049 12.4 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.1 EKG20001.1 - 0.063 12.1 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EKG20001.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TBP PF00352.16 EKG20002.1 - 3.6e-70 231.3 0.1 3.9e-35 119.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EKG20002.1 - 0.0001 22.2 0.0 0.4 10.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) IDO PF01231.13 EKG20003.1 - 8.7e-49 166.0 0.0 1.2e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF844 PF05815.6 EKG20005.1 - 0.014 14.2 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) DUF1240 PF06836.7 EKG20005.1 - 1.3 9.2 6.1 0.69 10.1 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1240) zf-UBP PF02148.14 EKG20006.1 - 0.067 13.3 0.3 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein MFS_1 PF07690.11 EKG20007.1 - 1.3e-30 106.3 23.6 1.9e-30 105.8 16.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20007.1 - 1.8e-29 102.6 20.8 5.2e-29 101.1 14.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Kelch_3 PF13415.1 EKG20008.1 - 2.7e-30 103.8 13.6 1.7e-06 28.0 0.1 7.6 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EKG20008.1 - 8.6e-26 89.4 3.7 6.3e-05 22.8 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.1 EKG20008.1 - 1e-22 79.5 20.9 5.8e-06 25.9 0.1 7.1 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EKG20008.1 - 3.3e-21 74.4 2.9 5.4e-05 23.1 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EKG20008.1 - 2.7e-15 55.6 2.2 0.0067 15.9 0.8 5.9 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EKG20008.1 - 3.1e-11 42.5 9.2 0.04 13.6 0.6 6.6 6 1 0 6 6 6 3 Kelch motif TPR_11 PF13414.1 EKG20009.1 - 0.00016 21.2 0.6 0.12 12.0 0.0 3.9 3 1 0 3 3 3 2 TPR repeat TPR_17 PF13431.1 EKG20009.1 - 0.0058 16.7 0.0 0.13 12.5 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 EKG20010.1 - 2.2e-155 517.2 0.0 3e-155 516.8 0.0 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EKG20010.1 - 1.4e-07 31.5 2.3 2.6 8.9 0.0 5.4 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG20010.1 - 0.00032 20.2 1.2 0.38 10.4 0.0 3.4 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EKG20010.1 - 0.00037 20.1 2.6 0.3 11.1 0.4 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG20010.1 - 0.00094 18.7 0.1 2.3 8.2 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKG20010.1 - 0.0013 19.0 0.0 0.56 10.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG20010.1 - 0.012 16.2 1.3 20 6.0 0.2 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EKG20010.1 - 0.042 13.4 1.6 11 5.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EKG20010.1 - 0.084 12.7 0.3 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_S24 PF00717.18 EKG20011.1 - 3.6e-05 23.3 0.0 4.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like NRDE PF05742.7 EKG20012.1 - 2.5e-45 154.9 0.0 4.3e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 NRDE protein KorB_C PF06613.6 EKG20012.1 - 0.081 12.3 0.1 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 KorB C-terminal beta-barrel domain TB2_DP1_HVA22 PF03134.14 EKG20013.1 - 4e-19 68.1 6.7 5.7e-19 67.6 4.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family WES_acyltransf PF03007.11 EKG20013.1 - 0.08 12.4 0.2 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Mgm101p PF06420.7 EKG20014.1 - 2e-89 297.4 0.0 2.6e-89 297.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 FGGY_C PF02782.11 EKG20015.1 - 2.7e-49 167.4 0.2 5.4e-49 166.5 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EKG20015.1 - 1.6e-23 83.3 1.0 1.2e-21 77.1 0.7 3.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EKG20015.1 - 0.00051 19.4 0.1 0.0039 16.5 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Ras PF00071.17 EKG20017.1 - 9.3e-41 138.9 0.0 9.2e-38 129.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EKG20017.1 - 6.8e-19 68.5 0.1 1e-18 67.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG20017.1 - 5.6e-14 51.7 0.0 8.6e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG20017.1 - 7e-07 28.6 0.0 9.4e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKG20017.1 - 0.00063 19.6 0.0 0.00091 19.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKG20017.1 - 0.0057 15.8 0.0 0.0079 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EKG20017.1 - 0.0069 16.3 0.1 0.014 15.3 0.0 1.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG20017.1 - 0.022 14.8 0.0 0.054 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EKG20017.1 - 0.029 13.9 0.1 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EKG20017.1 - 0.05 12.7 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG20017.1 - 0.083 13.7 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EKG20017.1 - 0.095 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EKG20017.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 EKG20017.1 - 0.15 11.5 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FMN_dh PF01070.13 EKG20018.1 - 1.2e-122 409.1 0.1 1.6e-122 408.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EKG20018.1 - 6.4e-23 80.3 0.0 1.3e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EKG20018.1 - 4.9e-07 28.9 0.0 8.4e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EKG20018.1 - 0.00033 19.6 0.3 0.0014 17.5 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EKG20018.1 - 0.006 15.8 0.7 0.43 9.7 0.0 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EKG20018.1 - 0.0069 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EKG20018.1 - 0.11 11.5 0.2 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG adh_short PF00106.20 EKG20019.1 - 2.8e-18 66.3 0.5 3.2e-18 66.2 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG20019.1 - 2.3e-12 46.9 0.5 3.1e-12 46.5 0.3 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG20019.1 - 0.00014 21.7 0.0 0.00015 21.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EKG20019.1 - 0.072 12.8 0.4 0.15 11.8 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EKG20019.1 - 0.076 12.0 0.1 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EKG20019.1 - 0.11 12.6 0.1 0.18 11.8 0.0 1.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Cyto_heme_lyase PF01265.12 EKG20020.1 - 5e-74 249.1 0.0 5.7e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase MFS_1 PF07690.11 EKG20021.1 - 2.6e-25 88.8 25.3 2.6e-25 88.8 17.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Paf67 PF10255.4 EKG20022.1 - 2.5e-156 520.6 0.1 2.9e-156 520.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EKG20022.1 - 0.02 14.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG20022.1 - 0.076 13.6 0.9 29 5.6 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKG20022.1 - 0.089 12.4 0.6 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 EKG20022.1 - 0.09 12.4 0.2 0.81 9.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CN_hydrolase PF00795.17 EKG20023.1 - 1.2e-29 103.0 0.0 1.6e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase peroxidase PF00141.18 EKG20024.1 - 6.8e-31 107.5 0.1 1.1e-30 106.8 0.1 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EKG20024.1 - 0.0031 17.3 0.0 0.007 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) p450 PF00067.17 EKG20025.1 - 1.9e-36 125.6 0.0 2.2e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ala_racemase_N PF01168.15 EKG20026.1 - 2.3e-46 158.0 0.3 2.9e-46 157.7 0.2 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DIM PF08194.7 EKG20027.1 - 0.086 12.8 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 DIM protein TPR_4 PF07721.9 EKG20028.1 - 0.31 11.5 0.2 0.31 11.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Tad PF13400.1 EKG20029.1 - 0.042 13.8 1.5 0.11 12.5 1.0 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like LEA_5 PF00477.12 EKG20029.1 - 0.09 13.0 0.8 0.09 13.0 0.6 1.7 2 0 0 2 2 2 0 Small hydrophilic plant seed protein XPG_I_2 PF12813.2 EKG20030.1 - 5.8e-46 156.9 0.0 3.3e-45 154.5 0.0 2.0 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc_N PF02739.11 EKG20030.1 - 0.019 14.3 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain ABM PF03992.11 EKG20032.1 - 0.055 13.5 0.3 4 7.5 0.1 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase ANAPC15 PF15243.1 EKG20033.1 - 5.3 7.1 9.6 9 6.4 0.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Sigma70_ner PF04546.8 EKG20033.1 - 7.2 6.1 14.5 2.5 7.6 2.2 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region TrwC PF08751.6 EKG20034.1 - 0.048 13.0 0.3 0.066 12.6 0.2 1.1 1 0 0 1 1 1 0 TrwC relaxase UPF0016 PF01169.14 EKG20035.1 - 6.9e-42 141.4 26.0 1.6e-21 76.2 5.2 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Med9 PF07544.8 EKG20035.1 - 0.11 12.2 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TPR_19 PF14559.1 EKG20037.1 - 7.8e-09 35.7 0.5 9.2e-05 22.7 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG20037.1 - 0.00027 20.7 3.4 0.00059 19.6 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EKG20037.1 - 0.0022 17.5 3.9 0.018 14.6 0.0 3.4 3 1 1 4 4 4 1 TPR repeat TPR_16 PF13432.1 EKG20037.1 - 0.0063 17.1 11.5 0.012 16.2 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EKG20037.1 - 0.014 16.0 8.7 3.4 8.5 0.2 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EKG20037.1 - 0.048 13.8 0.1 1 9.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EKG20037.1 - 0.052 13.6 1.7 0.93 9.6 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPP_enzyme_N PF02776.13 EKG20038.1 - 3.2e-56 189.5 0.0 1.1e-55 187.7 0.0 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EKG20038.1 - 1.2e-47 161.3 1.6 2.3e-46 157.1 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EKG20038.1 - 1.7e-37 128.2 2.0 2.4e-37 127.7 0.4 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EKG20038.1 - 0.02 14.4 0.0 0.049 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CRAL_TRIO PF00650.15 EKG20039.1 - 3.9e-11 42.6 0.0 6e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EKG20039.1 - 1.8e-06 27.9 0.2 6.1e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain PPR_2 PF13041.1 EKG20040.1 - 6.8e-21 73.9 0.3 9.1e-17 60.7 0.0 4.2 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 EKG20040.1 - 1.1e-07 31.6 7.3 0.00064 19.8 0.0 5.9 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 EKG20040.1 - 6.7e-06 25.4 0.0 0.0025 17.2 0.0 3.4 3 0 0 3 3 3 1 PPR repeat PPR PF01535.15 EKG20040.1 - 7.5e-06 25.5 4.8 1.1e-05 25.0 0.0 3.9 6 0 0 6 6 6 1 PPR repeat TPR_12 PF13424.1 EKG20040.1 - 0.0019 18.1 0.0 1.1 9.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG20040.1 - 0.0035 17.8 0.1 6 7.7 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2435 PF10363.4 EKG20040.1 - 0.017 15.0 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Pox_ATPase-GT PF10640.4 EKG20040.1 - 0.12 11.1 0.1 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase NARP1 PF12569.3 EKG20041.1 - 2.3 6.8 7.9 3.2 6.4 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1682 PF07946.9 EKG20041.1 - 5.2 5.8 8.9 6.8 5.4 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Apc15p PF05841.6 EKG20042.1 - 1.6 9.5 6.4 4.1 8.1 0.4 2.3 2 0 0 2 2 2 0 Apc15p protein DEAD PF00270.24 EKG20043.1 - 1.5e-45 154.6 0.0 5.5e-44 149.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG20043.1 - 1.2e-11 44.2 0.0 3.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG20043.1 - 0.00025 20.9 0.0 0.00084 19.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EKG20043.1 - 0.049 13.5 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain Phos_pyr_kin PF08543.7 EKG20044.1 - 5.9e-83 277.8 2.1 9.3e-83 277.1 1.4 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EKG20044.1 - 8.9e-54 182.4 0.3 1.3e-53 181.9 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EKG20044.1 - 2.6e-09 36.6 0.2 4.5e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TroA PF01297.12 EKG20044.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Periplasmic solute binding protein family HK PF02110.10 EKG20044.1 - 0.059 12.5 2.9 0.73 8.9 0.0 2.6 2 1 0 3 3 3 0 Hydroxyethylthiazole kinase family DNA_pol_lambd_f PF10391.4 EKG20044.1 - 0.092 12.3 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda LRR_4 PF12799.2 EKG20045.1 - 0.00017 21.1 5.2 0.59 9.8 0.0 4.7 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG20045.1 - 6.3 6.6 12.4 18 5.1 0.1 5.0 5 1 1 6 6 6 0 Leucine rich repeat Rad9 PF04139.8 EKG20046.1 - 4.4e-66 222.5 1.4 5.4e-66 222.2 1.0 1.1 1 0 0 1 1 1 1 Rad9 Prophage_tail PF06605.6 EKG20046.1 - 0.038 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Prophage endopeptidase tail MLANA PF14991.1 EKG20047.1 - 0.056 13.4 0.4 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 Protein melan-A Pyr_redox_3 PF13738.1 EKG20050.1 - 4.7e-25 88.8 0.0 7.5e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG20050.1 - 4.3e-20 71.4 2.1 1.2e-19 69.9 0.1 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EKG20050.1 - 1.1e-11 45.0 0.0 0.00011 22.1 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG20050.1 - 3.5e-11 42.6 0.2 2.6e-09 36.4 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EKG20050.1 - 6.1e-11 42.1 0.0 6.6e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG20050.1 - 4.1e-08 33.5 0.1 0.00012 22.3 0.0 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG20050.1 - 1.8e-06 27.1 0.0 0.0005 19.1 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EKG20050.1 - 5.5e-06 25.5 0.6 0.16 10.8 0.0 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG20050.1 - 6.1e-06 26.0 0.1 0.082 12.6 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 EKG20050.1 - 0.00025 20.2 0.0 0.052 12.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EKG20050.1 - 0.0038 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EKG20050.1 - 0.0046 16.6 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EKG20050.1 - 0.0053 15.2 0.3 0.54 8.6 0.0 2.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_7 PF13241.1 EKG20050.1 - 0.0087 16.2 0.0 0.042 14.1 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EKG20050.1 - 0.011 14.9 0.0 0.031 13.4 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG20050.1 - 0.018 14.9 0.1 0.28 11.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_2 PF03446.10 EKG20050.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EKG20050.1 - 0.027 13.8 0.0 0.46 9.9 0.0 2.4 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EKG20050.1 - 0.057 12.2 0.1 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 EKG20050.1 - 0.086 12.9 0.0 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ABC1 PF03109.11 EKG20051.1 - 8.5e-24 83.8 0.0 7.6e-14 51.7 0.0 2.5 1 1 0 2 2 2 2 ABC1 family RIO1 PF01163.17 EKG20051.1 - 0.006 15.9 0.0 0.091 12.1 0.0 2.3 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EKG20051.1 - 0.022 14.4 0.0 0.084 12.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3292 PF11696.3 EKG20052.1 - 1.2e-122 409.9 0.0 1.4e-122 409.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 EKG20052.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Actin PF00022.14 EKG20053.1 - 5.2e-42 143.6 0.0 1.3e-24 86.3 0.0 2.3 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.5 EKG20054.1 - 4e-29 100.3 5.1 4.4e-29 100.1 3.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Pecanex_C PF05041.10 EKG20054.1 - 0.019 13.9 0.2 0.022 13.8 0.2 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) GM_CSF PF01109.12 EKG20054.1 - 0.023 14.6 0.4 0.026 14.4 0.2 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 EKG20054.1 - 0.029 14.0 3.1 0.036 13.7 2.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 YL1_C PF08265.6 EKG20055.1 - 3.6e-16 58.4 0.2 6.7e-16 57.5 0.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.7 EKG20056.1 - 1.8e-19 69.9 12.8 2.1e-19 69.7 8.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2484 PF10658.4 EKG20056.1 - 1.1 9.4 10.0 0.045 13.8 2.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2484) YrhK PF14145.1 EKG20056.1 - 4.5 7.0 12.6 9.9 5.9 3.6 2.4 2 0 0 2 2 2 0 YrhK-like protein adh_short_C2 PF13561.1 EKG20058.1 - 2.1e-12 47.3 0.2 6.5e-12 45.7 0.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG20058.1 - 5.6e-12 45.8 0.0 8.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG20058.1 - 0.0019 17.8 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.17 EKG20059.1 - 1.6e-09 37.2 0.0 3.5e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG20059.1 - 1.6e-07 31.1 0.0 3.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKG20059.1 - 0.00084 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EKG20059.1 - 0.063 13.1 2.5 0.26 11.1 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif MFS_1 PF07690.11 EKG20060.1 - 1.6e-29 102.7 21.0 1.6e-25 89.6 0.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20060.1 - 2e-06 26.6 2.0 2e-06 26.6 1.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3392 PF11872.3 EKG20061.1 - 0.0012 18.7 1.5 0.0012 18.7 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3392) Metallophos PF00149.23 EKG20062.1 - 5e-07 29.3 2.7 9.8e-07 28.3 1.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L13e PF01294.13 EKG20063.1 - 9.7e-64 214.1 5.9 1.3e-63 213.6 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e DUF3123 PF11321.3 EKG20063.1 - 0.16 12.3 0.5 0.16 12.3 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) MMtag PF10159.4 EKG20063.1 - 0.35 10.9 0.1 0.35 10.9 0.1 2.0 2 0 0 2 2 2 0 Kinase phosphorylation protein GMC_oxred_C PF05199.8 EKG20064.1 - 2.2e-37 128.5 0.4 3.6e-37 127.8 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EKG20064.1 - 7.5e-26 90.9 0.0 1.2e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Glyco_transf_28 PF03033.15 EKG20065.1 - 8e-21 74.2 0.0 4.3e-20 71.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EKG20065.1 - 5.2e-05 21.9 0.0 7.9e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EKG20065.1 - 0.00055 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MOZART1 PF12554.3 EKG20066.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated BCS1_N PF08740.6 EKG20067.1 - 2.1e-39 135.0 0.3 3.8e-39 134.2 0.1 1.5 2 0 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 EKG20067.1 - 7e-19 68.3 0.0 1.9e-18 66.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG20067.1 - 5.3e-06 26.5 0.4 0.0058 16.6 0.1 2.9 1 1 1 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EKG20067.1 - 1.6e-05 25.7 0.0 7.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKG20067.1 - 5.1e-05 23.0 0.0 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EKG20067.1 - 7.4e-05 22.2 0.0 0.00019 20.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EKG20067.1 - 0.002 17.0 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 EKG20067.1 - 0.0025 17.3 0.0 0.0068 15.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EKG20067.1 - 0.0039 16.9 0.0 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EKG20067.1 - 0.011 15.9 0.0 0.035 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKG20067.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKG20067.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKG20067.1 - 0.018 15.0 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EKG20067.1 - 0.023 13.7 0.0 0.074 12.1 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_11 PF13086.1 EKG20067.1 - 0.035 13.6 0.0 0.094 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG20067.1 - 0.053 13.8 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EKG20067.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.1 EKG20067.1 - 0.061 13.1 0.0 0.18 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EKG20067.1 - 0.07 13.3 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_23 PF13476.1 EKG20067.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 EKG20067.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DUF258 PF03193.11 EKG20067.1 - 0.15 11.2 0.1 0.53 9.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EKG20067.1 - 0.16 11.6 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase OPT PF03169.10 EKG20068.1 - 6.1e-203 675.7 33.1 7.1e-203 675.4 22.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Yip1 PF04893.12 EKG20069.1 - 6.4e-06 25.7 18.7 2.5e-05 23.8 12.7 2.3 1 1 0 1 1 1 1 Yip1 domain Zn_clus PF00172.13 EKG20071.1 - 1.4e-06 28.0 7.9 4.2e-06 26.5 5.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EKG20071.1 - 0.00034 19.5 0.2 0.48 9.2 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain UcrQ PF02939.11 EKG20072.1 - 6.3e-25 86.8 0.2 8.2e-25 86.4 0.1 1.1 1 0 0 1 1 1 1 UcrQ family MRVI1 PF05781.7 EKG20074.1 - 0.12 10.7 0.1 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 MRVI1 protein DUF3657 PF12394.3 EKG20074.1 - 0.14 12.2 0.0 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3657) Pkinase PF00069.20 EKG20075.1 - 5.1e-06 25.8 0.1 6.2e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kinesin PF00225.18 EKG20076.1 - 7.9e-57 192.4 0.0 1.7e-56 191.3 0.0 1.5 1 1 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EKG20076.1 - 0.0052 16.5 0.9 0.0052 16.5 0.7 2.9 3 0 0 3 3 3 1 Basic region leucine zipper DLIC PF05783.6 EKG20076.1 - 0.57 8.7 2.5 0.38 9.3 0.0 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) DUF87 PF01935.12 EKG20076.1 - 1.5 8.6 4.4 5.4 6.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DBD_Tnp_Mut PF03108.10 EKG20077.1 - 1.5e-11 43.6 0.0 2.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 MuDR family transposase SPX PF03105.14 EKG20077.1 - 0.051 13.3 16.1 0.2 11.4 6.3 2.3 2 0 0 2 2 2 0 SPX domain Bud13 PF09736.4 EKG20077.1 - 0.076 13.2 21.3 0.053 13.7 9.0 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex LMBR1 PF04791.11 EKG20077.1 - 0.14 10.6 1.5 0.2 10.2 1.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spore_coat_CotO PF14153.1 EKG20077.1 - 0.94 8.8 27.2 0.41 10.0 11.4 2.2 2 0 0 2 2 2 0 Spore coat protein CotO CDC45 PF02724.9 EKG20077.1 - 2.4 6.0 21.3 1.8 6.4 1.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Lin-8 PF03353.10 EKG20077.1 - 2.7 7.1 25.8 3.3 6.9 10.6 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist SAGA-Tad1 PF12767.2 EKG20077.1 - 2.8 7.5 33.2 0.23 11.0 12.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit FLO_LFY PF01698.11 EKG20077.1 - 6.8 5.4 22.1 0.3 9.8 9.4 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein RCC1 PF00415.13 EKG20078.1 - 1.3e-34 118.1 12.8 1.1e-09 38.2 0.0 6.5 6 2 1 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKG20078.1 - 3.8e-25 86.8 20.2 7.1e-06 25.5 0.4 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S9 PF00380.14 EKG20079.1 - 1.7e-39 134.8 0.2 1.9e-39 134.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EKG20079.1 - 0.1 10.0 0.0 0.12 9.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein CDC45 PF02724.9 EKG20080.1 - 0.0017 16.5 5.4 0.0017 16.5 3.7 2.1 2 0 0 2 2 2 2 CDC45-like protein GFO_IDH_MocA_C PF02894.12 EKG20081.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain HTH_psq PF05225.11 EKG20081.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 helix-turn-helix, Psq domain adh_short PF00106.20 EKG20083.1 - 2e-05 24.5 0.7 2.7e-05 24.1 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase AdoHcyase_NAD PF00670.16 EKG20083.1 - 0.003 17.4 0.1 0.003 17.4 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.16 EKG20083.1 - 0.033 13.7 0.2 0.033 13.7 0.1 1.0 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 EKG20083.1 - 0.04 13.5 0.7 0.06 12.9 0.4 1.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MotA_activ PF09114.5 EKG20083.1 - 0.097 12.4 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Transcription factor MotA, activation domain adh_short_C2 PF13561.1 EKG20083.1 - 0.13 12.0 0.2 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase F-box-like PF12937.2 EKG20084.1 - 7.8e-05 22.3 2.7 0.00025 20.6 0.1 2.7 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EKG20084.1 - 0.0041 16.7 0.1 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 F-box domain LysM PF01476.15 EKG20085.1 - 0.00066 19.5 0.1 1.7 8.6 0.0 3.7 3 2 0 3 3 3 2 LysM domain E3_binding PF02817.12 EKG20085.1 - 0.059 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 e3 binding domain MFS_1 PF07690.11 EKG20086.1 - 1.9e-33 115.6 18.2 1.9e-33 115.6 12.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20086.1 - 5e-19 68.2 0.3 5e-19 68.2 0.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EKG20086.1 - 0.00011 20.5 1.5 0.0002 19.7 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_U4 PF03419.8 EKG20087.1 - 0.09 11.8 0.2 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Form_Nir_trans PF01226.12 EKG20088.1 - 4.6e-73 245.1 13.1 5.3e-73 245.0 9.1 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF1470 PF07336.6 EKG20089.1 - 0.013 15.7 3.2 2.8 8.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) Inhibitor_I24 PF10465.4 EKG20090.1 - 0.061 13.0 0.2 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 PinA peptidase inhibitor MR_MLE PF01188.16 EKG20090.1 - 0.097 13.2 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Reprolysin_4 PF13583.1 EKG20094.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Adaptin_N PF01602.15 EKG20095.1 - 7.2e-122 407.3 6.3 9.6e-122 406.9 4.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EKG20095.1 - 2.6e-45 152.9 0.0 6.6e-45 151.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EKG20095.1 - 1.3e-21 77.0 0.1 2.4e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF1096 PF06493.6 EKG20096.1 - 0.22 11.5 40.3 0.058 13.3 11.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) TFIIB PF00382.14 EKG20097.1 - 1.1e-28 98.7 1.2 1.2e-18 66.6 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EKG20097.1 - 1.2e-21 76.7 3.0 9.5e-21 73.8 0.1 2.9 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EKG20097.1 - 0.00087 18.5 2.2 0.0037 16.5 1.5 2.1 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EKG20097.1 - 0.023 14.2 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain p450 PF00067.17 EKG20098.1 - 1.6e-44 152.1 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2584 PF10763.4 EKG20098.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) PHD PF00628.24 EKG20099.1 - 3.1e-08 33.1 3.2 4.7e-08 32.5 2.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EKG20099.1 - 0.00034 19.9 0.2 0.00049 19.4 0.1 1.2 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EKG20099.1 - 0.38 10.1 9.4 1.6 8.0 6.5 1.9 1 1 0 1 1 1 0 PHD-finger Mito_fiss_reg PF05308.6 EKG20099.1 - 1.1 8.5 5.8 1.7 7.9 4.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CoA_transf_3 PF02515.12 EKG20100.1 - 4.4e-60 202.1 0.1 6.7e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 EKG20101.1 - 8.2e-40 134.5 2.0 3.7e-23 81.2 0.5 2.2 2 0 0 2 2 2 2 Lumazine binding domain Methyltransf_31 PF13847.1 EKG20103.1 - 8.7e-12 44.8 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EKG20103.1 - 2.7e-10 39.8 0.0 4.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EKG20103.1 - 1.1e-08 35.6 0.0 2.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG20103.1 - 1.5e-08 35.0 0.0 3.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EKG20103.1 - 4.5e-08 32.4 0.0 5.2e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 EKG20103.1 - 1.7e-07 31.2 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EKG20103.1 - 2.1e-05 23.4 0.0 3.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EKG20103.1 - 2.9e-05 24.3 0.0 5.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG20103.1 - 0.00024 20.8 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG20103.1 - 0.00026 21.4 0.0 0.00052 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EKG20103.1 - 0.00027 20.1 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EKG20103.1 - 0.00091 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EKG20103.1 - 0.033 15.0 0.0 0.068 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EKG20103.1 - 0.046 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EKG20103.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 UFD1 PF03152.9 EKG20104.1 - 1.6e-19 69.7 0.0 8.4e-19 67.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 zf-C2H2_6 PF13912.1 EKG20104.1 - 0.0034 17.2 2.4 0.0034 17.2 1.6 3.7 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 EKG20104.1 - 1.8 8.8 8.7 0.63 10.3 1.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type F-box PF00646.28 EKG20105.1 - 0.00083 18.9 0.7 0.02 14.5 0.0 3.1 3 0 0 3 3 3 1 F-box domain YLP PF02757.12 EKG20105.1 - 1.4 8.8 4.3 10 6.2 0.2 2.8 2 0 0 2 2 2 0 YLP motif TFIIB PF00382.14 EKG20106.1 - 3.6e-32 110.0 0.0 9.8e-15 54.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EKG20106.1 - 8.4e-13 47.4 0.6 1.3e-12 46.7 0.4 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.1 EKG20106.1 - 0.00097 18.2 0.0 0.084 12.0 0.0 3.1 3 1 0 3 3 3 1 Helix-turn-helix domain of transposase family ISL3 Cyclin_C PF02984.14 EKG20106.1 - 0.001 18.9 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain HTH_20 PF12840.2 EKG20106.1 - 0.01 15.6 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.1 EKG20106.1 - 0.021 14.4 0.0 0.4 10.3 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Rrf2 PF02082.15 EKG20106.1 - 0.021 14.9 0.0 9.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator zf-ribbon_3 PF13248.1 EKG20106.1 - 0.025 13.7 0.4 0.061 12.5 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain HTH_24 PF13412.1 EKG20106.1 - 0.042 13.2 0.0 3.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding PhnA_Zn_Ribbon PF08274.7 EKG20106.1 - 0.069 12.9 0.4 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Trp_repressor PF01371.14 EKG20106.1 - 0.077 12.9 0.0 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Trp repressor protein Sigma70_r4 PF04545.11 EKG20106.1 - 0.12 11.6 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 ATP_sub_h PF10775.4 EKG20107.1 - 4.1e-26 90.5 1.0 5.7e-26 90.0 0.7 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EKG20107.1 - 0.0039 17.0 0.2 0.0083 16.0 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 DUF1765 PF08578.5 EKG20108.1 - 3.6e-38 130.4 4.6 4.7e-38 130.0 2.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) peroxidase PF00141.18 EKG20109.1 - 1.8e-34 119.2 0.3 2.8e-34 118.5 0.2 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EKG20109.1 - 2.4e-06 27.3 0.0 5.4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) AAA PF00004.24 EKG20111.1 - 1e-43 148.6 0.0 1.7e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG20111.1 - 4.1e-08 33.0 0.0 9.8e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EKG20111.1 - 7.6e-08 32.4 0.0 1.5e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EKG20111.1 - 3.3e-06 27.2 0.0 7.8e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EKG20111.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG20111.1 - 7e-05 23.6 0.0 0.00015 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EKG20111.1 - 7.3e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EKG20111.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EKG20111.1 - 0.00039 19.8 0.0 0.00076 18.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EKG20111.1 - 0.00088 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EKG20111.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKG20111.1 - 0.0017 18.2 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EKG20111.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EKG20111.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EKG20111.1 - 0.0037 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG20111.1 - 0.0064 16.7 0.0 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EKG20111.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EKG20111.1 - 0.0072 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC Sigma54_activat PF00158.21 EKG20111.1 - 0.017 14.6 0.0 0.085 12.3 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF815 PF05673.8 EKG20111.1 - 0.017 14.0 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EKG20111.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKG20111.1 - 0.021 14.2 0.1 0.079 12.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EKG20111.1 - 0.022 13.9 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EKG20111.1 - 0.03 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EKG20111.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EKG20111.1 - 0.051 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EKG20111.1 - 0.079 11.8 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 EKG20111.1 - 0.082 12.8 0.1 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Histone PF00125.19 EKG20111.1 - 0.099 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EKG20111.1 - 0.1 12.2 0.0 0.55 9.8 0.0 2.0 1 1 0 2 2 2 0 NACHT domain DivIC PF04977.10 EKG20111.1 - 0.43 10.1 2.8 0.35 10.3 0.7 1.7 2 0 0 2 2 1 0 Septum formation initiator Na_Ca_ex PF01699.19 EKG20112.1 - 4.6e-34 117.0 22.0 6.9e-20 71.0 5.7 3.5 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EKG20112.1 - 3.2e-14 53.0 11.7 3.2e-14 53.0 8.1 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF307) CMD PF02627.15 EKG20112.1 - 0.13 12.1 1.5 0.33 10.8 0.4 2.1 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family PAN_4 PF14295.1 EKG20113.1 - 0.049 13.3 5.5 0.17 11.5 0.1 2.9 3 1 0 3 3 3 0 PAN domain DPM3 PF08285.6 EKG20115.1 - 3.8e-34 116.3 0.1 4.2e-34 116.2 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Oxidored-like PF09791.4 EKG20116.1 - 1.5e-26 91.5 3.3 2.9e-26 90.6 2.3 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal CENP-P PF13096.1 EKG20117.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUF3922 PF13059.1 EKG20117.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Surfac_D-trimer PF09006.6 EKG20117.1 - 0.29 10.9 1.0 0.5 10.1 0.7 1.4 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation DivIC PF04977.10 EKG20117.1 - 0.7 9.4 3.4 1.3 8.5 2.4 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF1049 PF06305.6 EKG20117.1 - 0.91 9.0 2.8 1.9 8.0 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) MFS_1 PF07690.11 EKG20120.1 - 2.1e-25 89.2 50.5 1.1e-19 70.3 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EKG20123.1 - 5.4e-23 81.6 0.0 9.9e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Kinetocho_Slk19 PF12709.2 EKG20124.1 - 1.7e-16 60.0 30.6 4.8e-16 58.6 5.6 4.3 4 0 0 4 4 4 2 Central kinetochore-associated Uds1 PF15456.1 EKG20124.1 - 0.0012 18.7 34.2 0.022 14.7 10.7 3.7 3 0 0 3 3 3 2 Up-regulated During Septation TMF_DNA_bd PF12329.3 EKG20124.1 - 0.0038 16.9 6.4 0.0038 16.9 4.4 4.8 3 2 0 4 4 4 2 TATA element modulatory factor 1 DNA binding CDC37_N PF03234.9 EKG20124.1 - 0.0046 17.3 13.9 0.0046 17.3 9.7 3.5 2 2 1 3 3 3 1 Cdc37 N terminal kinase binding DUF4407 PF14362.1 EKG20124.1 - 0.02 13.8 31.9 0.028 13.3 7.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.4 EKG20124.1 - 0.046 13.5 48.9 0.25 11.1 4.2 4.5 4 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EKG20124.1 - 0.2 11.0 45.2 3.5 7.0 4.1 2.3 1 1 1 2 2 2 0 Intermediate filament protein NPV_P10 PF05531.7 EKG20124.1 - 0.28 11.4 6.7 2.6 8.3 0.4 4.0 3 1 1 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 EKG20124.1 - 0.92 9.4 45.2 0.29 11.1 2.4 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 EKG20124.1 - 1.6 8.5 4.3 44 3.8 0.0 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 EKG20124.1 - 1.7 8.4 51.4 0.014 15.2 14.9 4.0 4 0 0 4 4 4 0 Tropomyosin like Prominin PF05478.6 EKG20124.1 - 2.3 5.6 8.2 4.2 4.7 5.7 1.4 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.5 EKG20124.1 - 8.9 6.4 15.4 3.8 7.6 0.1 3.7 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SMC_Nse1 PF07574.8 EKG20125.1 - 2.5e-33 115.4 0.0 3.3e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex YhfH PF14149.1 EKG20125.1 - 0.066 13.0 0.1 0.066 13.0 0.0 1.8 2 0 0 2 2 2 0 YhfH-like protein zf-C3HC4_3 PF13920.1 EKG20125.1 - 0.075 12.7 1.3 0.12 12.0 0.9 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1018 PF06252.7 EKG20125.1 - 0.12 12.9 0.1 0.95 9.9 0.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1018) Glucosamine_iso PF01182.15 EKG20126.1 - 4.5e-22 78.7 0.0 7.6e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MFS_1 PF07690.11 EKG20127.1 - 5e-09 35.3 42.2 8e-09 34.6 28.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EKG20127.1 - 2.2e-08 33.7 10.8 2.2e-08 33.7 7.5 3.5 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 Hexokinase_2 PF03727.11 EKG20128.1 - 7.6e-40 136.6 0.0 1.1e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EKG20128.1 - 8.9e-36 123.1 0.0 1.3e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase NDT80_PhoG PF05224.7 EKG20131.1 - 7.9e-37 127.0 0.1 7.9e-37 127.0 0.0 1.6 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Glyco_hydro_3 PF00933.16 EKG20132.1 - 1.9e-53 181.3 0.0 2.7e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EKG20132.1 - 2.8e-05 24.0 0.0 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 EKG20132.1 - 0.0002 20.9 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.1 EKG20132.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Amidohydro_4 PF13147.1 EKG20133.1 - 1.1e-14 55.1 1.2 2.4e-13 50.7 0.8 2.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EKG20133.1 - 1.5e-09 37.9 0.1 1.4e-05 24.9 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EKG20133.1 - 2.6e-07 30.2 0.3 1.2e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EKG20133.1 - 3.5e-05 23.5 0.0 0.0001 22.0 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Na_Ca_ex PF01699.19 EKG20134.1 - 3.4e-41 140.1 33.9 2.2e-23 82.4 9.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Snf7 PF03357.16 EKG20135.1 - 8.9e-16 57.7 13.9 8.9e-16 57.7 9.6 2.5 1 1 2 3 3 3 1 Snf7 CBFD_NFYB_HMF PF00808.18 EKG20135.1 - 1.9e-15 56.6 1.2 1.9e-15 56.6 0.9 2.7 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EKG20135.1 - 0.023 14.7 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TPR_MLP1_2 PF07926.7 EKG20135.1 - 1.4 8.6 18.5 1.9 8.2 10.8 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein adh_short PF00106.20 EKG20136.1 - 7.5e-31 107.2 1.7 1.1e-30 106.7 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG20136.1 - 4.4e-18 65.9 0.0 5.8e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG20136.1 - 4.5e-13 49.2 0.9 6.4e-13 48.7 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG20136.1 - 1.8e-05 24.8 0.4 3.1e-05 24.0 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG20136.1 - 7.8e-05 22.2 0.0 0.0033 16.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EKG20136.1 - 0.00055 18.9 0.0 0.0012 17.7 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EKG20136.1 - 0.0013 18.6 0.2 0.091 12.7 0.0 2.5 3 0 0 3 3 3 1 TrkA-N domain PP2C_2 PF13672.1 EKG20136.1 - 0.0026 17.2 0.1 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Glyco_tran_WecB PF03808.8 EKG20136.1 - 0.0059 16.0 0.1 0.019 14.3 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.15 EKG20136.1 - 0.014 15.4 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 EKG20136.1 - 0.1 11.6 0.1 0.76 8.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.19 EKG20137.1 - 3.4e-43 147.9 2.6 1e-42 146.3 1.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EKG20137.1 - 1.1e-05 25.6 0.0 0.098 13.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG20137.1 - 0.00044 20.1 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG20137.1 - 0.0022 17.1 0.1 0.27 10.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG20137.1 - 0.0069 16.3 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EKG20137.1 - 0.0079 14.8 0.0 1.5 7.3 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Strep_67kDa_ant PF06100.6 EKG20137.1 - 0.081 11.2 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 EKG20137.1 - 0.1 12.3 0.3 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding SAC3_GANP PF03399.11 EKG20138.1 - 8.9e-07 28.6 0.1 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EKG20138.1 - 0.00063 19.5 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HlyIII PF03006.15 EKG20139.1 - 3e-54 183.7 9.9 3.6e-54 183.5 6.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4405 PF14358.1 EKG20139.1 - 7 6.8 9.4 0.35 11.0 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4405) Glyco_hydro_17 PF00332.13 EKG20140.1 - 1.8e-09 37.0 1.4 1e-08 34.6 1.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 ABA_GPCR PF12430.3 EKG20141.1 - 2.7e-58 196.3 0.1 3.3e-58 196.0 0.1 1.0 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF2798 PF11391.3 EKG20141.1 - 0.13 12.0 3.0 0.19 11.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) BRCT PF00533.21 EKG20143.1 - 0.00053 20.0 0.1 0.001 19.1 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain HET PF06985.6 EKG20144.1 - 5e-35 120.6 0.1 9.6e-35 119.7 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TIP41 PF04176.8 EKG20144.1 - 0.16 11.2 0.0 0.43 9.8 0.0 1.7 1 0 0 1 1 1 0 TIP41-like family SLAC1 PF03595.12 EKG20145.1 - 9.6e-82 274.2 39.7 1.1e-81 274.0 27.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF2890 PF11081.3 EKG20145.1 - 0.31 11.0 3.8 0.61 10.1 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Thiolase_N PF00108.18 EKG20146.1 - 2.1e-78 262.9 0.5 3.3e-78 262.3 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EKG20146.1 - 5.4e-44 148.5 0.5 1.4e-43 147.2 0.3 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain AreA_N PF07573.6 EKG20146.1 - 0.012 16.1 0.1 0.037 14.5 0.0 1.9 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus ketoacyl-synt PF00109.21 EKG20146.1 - 0.046 13.1 4.8 0.08 12.4 2.6 2.0 1 1 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF3245 PF11595.3 EKG20147.1 - 6.2e-25 88.2 8.7 6.2e-25 88.2 6.0 3.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) ATP-grasp_2 PF08442.5 EKG20148.1 - 3.4e-78 261.6 0.7 5.9e-78 260.8 0.5 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EKG20148.1 - 3.2e-26 91.7 0.3 6.3e-26 90.8 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EKG20148.1 - 2.1e-10 40.1 0.4 5e-10 38.9 0.3 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EKG20148.1 - 0.0028 17.2 0.7 0.036 13.6 0.1 2.5 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 EKG20148.1 - 0.021 13.9 1.6 0.029 13.5 0.3 1.8 2 0 0 2 2 2 0 Periplasmic binding protein Pkinase PF00069.20 EKG20151.1 - 4.1e-61 206.4 0.0 5.5e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20151.1 - 5.5e-33 114.1 0.0 6.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG20151.1 - 0.00012 21.9 0.0 0.00028 20.6 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG20151.1 - 0.0007 18.6 0.0 0.0012 17.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG20151.1 - 0.011 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EKG20151.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase UL11 PF11094.3 EKG20151.1 - 0.097 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated tegument protein Pox_ser-thr_kin PF05445.6 EKG20151.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrhK PF14145.1 EKG20152.1 - 7.2e-05 22.3 19.7 0.12 12.0 0.4 5.0 3 2 1 4 4 4 3 YrhK-like protein Arrestin_N PF00339.24 EKG20153.1 - 6.8e-05 22.7 0.0 0.00076 19.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Pyridoxal_deC PF00282.14 EKG20154.1 - 2.5e-11 42.6 0.0 4.2e-05 22.1 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain GDC-P PF02347.11 EKG20155.1 - 1.8e-181 603.5 0.0 5.2e-166 552.5 0.0 2.2 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EKG20155.1 - 2.1e-08 33.6 0.0 4.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EKG20155.1 - 3.7e-08 32.5 0.3 0.00012 20.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EKG20155.1 - 0.00023 20.3 0.1 0.0082 15.2 0.0 2.2 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family RCC1 PF00415.13 EKG20156.1 - 2.3e-55 184.5 3.5 5e-12 45.8 0.0 7.9 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EKG20156.1 - 4.1e-34 115.4 29.4 1.7e-09 37.0 0.1 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Macoilin PF09726.4 EKG20156.1 - 1.7 6.8 9.4 2.1 6.5 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Utp21 PF04192.7 EKG20157.1 - 1.3e-73 247.0 0.0 1.9e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EKG20157.1 - 2.5e-22 77.8 30.3 1.8e-05 24.4 0.1 9.3 10 0 0 10 10 10 4 WD domain, G-beta repeat Utp12 PF04003.7 EKG20157.1 - 9.6e-06 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Cytochrom_D1 PF02239.11 EKG20157.1 - 7.5e-05 21.1 0.0 0.00053 18.4 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EKG20157.1 - 0.00013 20.8 0.6 0.72 8.5 0.0 3.5 2 1 0 3 3 3 2 Nup133 N terminal like CNH PF00780.17 EKG20157.1 - 0.18 11.1 0.0 8.3 5.7 0.0 2.5 2 0 0 2 2 2 0 CNH domain Lgl_C PF08596.5 EKG20157.1 - 0.19 10.1 0.0 0.91 7.9 0.0 2.0 3 0 0 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal Colicin_Pyocin PF01320.13 EKG20157.1 - 0.22 11.4 0.3 1.2 9.0 0.2 2.2 1 1 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein His_Phos_2 PF00328.17 EKG20158.1 - 3.5e-120 401.4 0.3 4.7e-120 401.0 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EKG20158.1 - 9.1e-07 28.5 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain AAR2 PF05282.6 EKG20159.1 - 0.0033 16.4 0.1 0.0057 15.6 0.1 1.4 1 0 0 1 1 1 1 AAR2 protein AAR2 PF05282.6 EKG20160.1 - 2.5e-45 154.9 0.0 3e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.14 EKG20161.1 - 6.6e-41 138.9 0.6 8e-41 138.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EKG20161.1 - 0.042 12.7 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) PDH PF02153.12 EKG20162.1 - 6.3e-16 58.0 0.0 9.1e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EKG20162.1 - 8.3e-07 28.9 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EKG20162.1 - 1.4e-05 25.4 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EKG20162.1 - 0.00076 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EKG20162.1 - 0.008 15.9 0.0 0.051 13.2 0.0 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EKG20162.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EKG20162.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EKG20162.1 - 0.044 13.4 0.0 0.091 12.4 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.7 EKG20162.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Btz PF09405.5 EKG20163.1 - 0.013 15.5 0.3 0.013 15.5 0.2 2.2 2 0 0 2 2 2 0 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 EKG20163.1 - 0.04 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyclase PF04199.8 EKG20164.1 - 1.6e-10 40.9 0.1 2.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Amidase PF01425.16 EKG20166.1 - 3.9e-114 381.9 1.1 4.9e-114 381.5 0.8 1.0 1 0 0 1 1 1 1 Amidase bZIP_2 PF07716.10 EKG20168.1 - 0.0001 22.0 12.9 0.00019 21.1 9.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EKG20168.1 - 0.00084 19.2 12.2 0.0017 18.2 8.5 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EKG20168.1 - 0.12 12.7 9.5 0.21 11.8 6.6 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor CAF-1_p150 PF11600.3 EKG20168.1 - 7.5 5.8 27.3 0.015 14.7 10.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nic96 PF04097.9 EKG20170.1 - 2.1e-162 541.4 0.1 2.6e-162 541.1 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Med27 PF11571.3 EKG20172.1 - 2.1e-17 63.0 0.0 1.4e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 27 Lactamase_B_2 PF12706.2 EKG20173.1 - 7e-40 136.6 0.0 9.1e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG20173.1 - 1.9e-11 43.9 0.0 3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EKG20173.1 - 4.2e-05 23.2 1.4 0.0039 16.8 0.5 2.7 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily CFEM PF05730.6 EKG20174.1 - 4.5e-09 35.9 2.4 6.8e-09 35.4 1.7 1.3 1 0 0 1 1 1 1 CFEM domain X_fast-SP_rel PF06669.6 EKG20175.1 - 0.017 15.0 0.1 0.039 13.8 0.1 1.6 1 0 0 1 1 1 0 Xylella fastidiosa surface protein related Metallophos PF00149.23 EKG20176.1 - 1.2e-06 28.1 6.2 1.1e-05 24.9 4.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EKG20176.1 - 0.00048 20.0 0.0 0.00091 19.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.7 EKG20177.1 - 8.7e-117 390.5 0.7 1e-116 390.2 0.5 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel ABC_membrane PF00664.18 EKG20177.1 - 0.031 13.6 0.1 0.031 13.6 0.1 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region PAP_assoc PF03828.14 EKG20178.1 - 1.3e-09 37.8 0.0 3.1e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EKG20178.1 - 4e-08 33.4 0.0 8.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pam16 PF03656.8 EKG20179.1 - 2.6e-33 114.5 0.5 3.4e-33 114.1 0.3 1.1 1 0 0 1 1 1 1 Pam16 Pex24p PF06398.6 EKG20180.1 - 2.1e-81 273.5 0.0 2.5e-81 273.2 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3445 PF11927.3 EKG20183.1 - 8.6e-68 228.4 0.0 1e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) dCMP_cyt_deam_1 PF00383.17 EKG20184.1 - 0.024 14.2 0.8 0.042 13.5 0.6 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region PAT1 PF09770.4 EKG20185.1 - 2.2 6.4 15.7 2.5 6.2 10.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OmpH PF03938.9 EKG20185.1 - 2.8 7.8 8.8 3.9 7.3 6.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PPP4R2 PF09184.6 EKG20185.1 - 6 6.3 10.8 6.7 6.1 7.5 1.1 1 0 0 1 1 1 0 PPP4R2 Ish1 PF10281.4 EKG20186.1 - 1.5e-54 181.6 23.8 1.6e-14 53.6 0.0 5.6 5 0 0 5 5 5 5 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EKG20186.1 - 1.1e-06 28.0 0.0 0.6 9.7 0.0 4.2 4 0 0 4 4 4 2 HeH/LEM domain SAP PF02037.22 EKG20186.1 - 1.2e-05 24.6 0.0 0.17 11.4 0.0 4.0 4 0 0 4 4 4 2 SAP domain APC2 PF08672.6 EKG20186.1 - 0.0037 17.4 0.5 44 4.4 0.0 4.6 5 0 0 5 5 5 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.5 EKG20186.1 - 0.0068 16.1 4.8 2.1 8.1 0.0 3.9 5 0 0 5 5 5 1 Slx4 endonuclease SAM_2 PF07647.12 EKG20186.1 - 0.02 14.7 2.0 20 5.1 0.0 4.1 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Amidase02_C PF12123.3 EKG20186.1 - 0.039 13.5 0.4 13 5.5 0.0 3.4 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase DUF2296 PF10058.4 EKG20188.1 - 6.2e-20 70.6 0.1 1e-19 70.0 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF4463 PF14703.1 EKG20188.1 - 0.011 16.2 0.1 0.035 14.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) AA_permease PF00324.16 EKG20188.1 - 0.029 12.7 0.3 0.04 12.2 0.2 1.1 1 0 0 1 1 1 0 Amino acid permease Complex1_LYR PF05347.10 EKG20189.1 - 0.00099 18.8 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EKG20189.1 - 0.062 13.5 0.3 0.085 13.0 0.2 1.4 1 1 0 1 1 1 0 Complex1_LYR-like RRM_1 PF00076.17 EKG20190.1 - 3.8e-09 36.0 0.0 6.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG20190.1 - 8e-09 35.2 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG20190.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKG20190.1 - 0.03 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EKG20191.1 - 2e-28 98.1 0.1 3.9e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EKG20191.1 - 3.2e-20 72.4 0.0 5.9e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG20191.1 - 1.9e-16 59.9 0.0 5e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG20191.1 - 1.4e-14 54.1 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG20191.1 - 2.2e-12 47.2 0.0 3.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EKG20191.1 - 4.5e-10 39.0 0.0 6.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EKG20191.1 - 1.1e-09 38.7 0.0 2.3e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG20191.1 - 2.6e-09 36.5 0.0 4.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EKG20191.1 - 5.4e-09 36.6 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG20191.1 - 1.7e-08 34.5 0.0 4.9e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG20191.1 - 5.1e-05 22.7 0.0 9.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 EKG20191.1 - 0.0012 17.2 0.0 0.0017 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.5 EKG20191.1 - 0.0031 17.0 0.1 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EKG20191.1 - 0.0092 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EKG20191.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EKG20191.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UPF0020 PF01170.13 EKG20191.1 - 0.05 13.1 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.7 EKG20191.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Transket_pyr PF02779.19 EKG20192.1 - 7.3e-49 165.6 0.0 1.1e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EKG20192.1 - 4.9e-34 116.9 0.1 1.3e-33 115.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain GntR PF00392.16 EKG20192.1 - 0.00019 20.8 0.6 0.0042 16.4 0.1 2.4 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family DUF460 PF04312.8 EKG20192.1 - 0.13 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Pribosyltran PF00156.22 EKG20193.1 - 7.5e-11 41.8 0.0 3e-10 39.8 0.0 1.9 2 1 0 2 2 2 1 Phosphoribosyl transferase domain F-box-like PF12937.2 EKG20194.1 - 4.2e-09 35.9 0.1 1.1e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like HSF_DNA-bind PF00447.12 EKG20195.1 - 3.5e-36 123.5 1.1 6e-36 122.7 0.8 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Menin PF05053.8 EKG20195.1 - 0.24 9.4 6.3 0.39 8.8 4.3 1.2 1 0 0 1 1 1 0 Menin SSP160 PF06933.6 EKG20195.1 - 5.8 4.7 14.2 8.5 4.2 9.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BTB PF00651.26 EKG20196.1 - 6.7e-08 32.5 0.0 2.4e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EKG20196.1 - 0.032 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Y_phosphatase PF00102.22 EKG20197.1 - 2e-60 204.0 0.0 1.2e-31 109.8 0.0 3.1 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 EKG20197.1 - 1.5e-09 38.1 0.0 1.1e-08 35.3 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EKG20197.1 - 0.007 15.9 0.3 0.014 14.9 0.2 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EKG20197.1 - 0.022 14.9 0.1 0.051 13.8 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Sigma54_activ_2 PF14532.1 EKG20197.1 - 0.08 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AbbA_antirepres PF14156.1 EKG20197.1 - 0.28 10.8 0.5 0.67 9.6 0.1 1.8 2 0 0 2 2 2 0 Antirepressor AbbA F-box-like PF12937.2 EKG20198.1 - 0.00029 20.5 0.2 0.00063 19.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG20198.1 - 0.00081 18.9 0.1 0.0019 17.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 EKG20200.1 - 1.6e-50 171.6 0.1 2.8e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20200.1 - 8.3e-21 74.2 0.0 3.7e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EKG20200.1 - 0.028 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EKG20200.1 - 0.049 12.9 1.0 0.087 12.1 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EKG20202.1 - 6.5e-40 136.9 0.2 5.8e-24 84.6 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20202.1 - 9.1e-15 54.4 0.3 1.8e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase GRIP PF01465.15 EKG20203.1 - 1.4e-17 62.9 0.3 3.1e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 EKG20203.1 - 2.2e-08 33.6 54.5 0.0001 21.6 3.3 7.1 2 2 6 8 8 8 5 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EKG20203.1 - 1e-07 30.1 186.6 8.4e-05 20.5 24.4 5.1 2 2 3 5 5 5 4 Myosin tail GAS PF13851.1 EKG20203.1 - 1.5e-07 30.8 166.3 0.00012 21.3 13.2 10.2 4 2 5 10 10 10 7 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EKG20203.1 - 7.8e-05 22.5 185.1 0.22 11.3 14.8 9.5 2 2 6 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EKG20203.1 - 8.4e-05 22.2 186.5 0.075 12.6 8.5 10.5 2 2 9 11 11 11 7 IncA protein Phage_GP20 PF06810.6 EKG20203.1 - 0.00039 19.9 1.4 0.00039 19.9 0.9 12.1 2 2 11 13 13 11 2 Phage minor structural protein GP20 Spc7 PF08317.6 EKG20203.1 - 0.00048 18.8 9.8 0.00048 18.8 6.8 8.2 2 2 6 9 9 9 4 Spc7 kinetochore protein AAA_13 PF13166.1 EKG20203.1 - 0.0014 17.1 26.3 0.0014 17.1 18.3 6.8 2 2 4 6 6 6 2 AAA domain DUF869 PF05911.6 EKG20203.1 - 0.0025 16.1 143.9 0.017 13.4 19.3 4.8 1 1 3 4 4 4 2 Plant protein of unknown function (DUF869) MscS_porin PF12795.2 EKG20203.1 - 0.0027 17.0 23.0 0.0027 17.0 16.0 7.7 4 2 3 7 7 7 5 Mechanosensitive ion channel porin domain TBPIP PF07106.8 EKG20203.1 - 0.0029 17.1 9.6 0.0029 17.1 6.6 10.7 3 2 7 11 11 11 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FH2 PF02181.18 EKG20203.1 - 0.0038 16.1 5.7 0.0038 16.1 4.0 8.9 5 3 4 9 9 9 5 Formin Homology 2 Domain APG6 PF04111.7 EKG20203.1 - 0.004 16.2 12.0 0.004 16.2 8.3 8.5 2 2 5 8 8 7 4 Autophagy protein Apg6 Filament PF00038.16 EKG20203.1 - 0.93 8.8 163.4 0.13 11.6 21.5 8.6 3 2 5 8 8 8 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 EKG20203.1 - 7.2 6.3 174.5 0.13 11.9 10.5 9.8 4 2 4 9 9 9 0 TPR/MLP1/MLP2-like protein DnaJ PF00226.26 EKG20204.1 - 1.9e-19 69.1 1.0 1.9e-19 69.1 0.7 2.7 3 0 0 3 3 3 1 DnaJ domain Usp PF00582.21 EKG20205.1 - 3.3e-10 40.3 0.0 7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family Ferric_reduct PF01794.14 EKG20206.1 - 2.8e-16 59.7 14.5 2.8e-16 59.7 10.0 2.1 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EKG20206.1 - 1.8e-07 30.9 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EKG20206.1 - 2.5e-07 30.7 0.0 0.002 18.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain MFS_1 PF07690.11 EKG20207.1 - 4.1e-14 52.0 85.1 2.6e-11 42.8 38.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20207.1 - 9.1e-05 21.2 11.9 9.1e-05 21.2 8.2 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter Pex14_N PF04695.8 EKG20208.1 - 1.9e-35 121.8 7.7 1.5e-34 118.9 0.0 3.0 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Filament PF00038.16 EKG20208.1 - 0.039 13.4 2.4 0.058 12.8 1.7 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF641 PF04859.7 EKG20208.1 - 0.055 13.2 0.2 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Cytochrom_B562 PF07361.6 EKG20208.1 - 0.056 13.8 1.6 0.12 12.7 1.1 1.6 1 0 0 1 1 1 0 Cytochrome b562 Sipho_Gp157 PF05565.6 EKG20208.1 - 0.067 12.7 5.5 0.13 11.8 1.1 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 DUF3584 PF12128.3 EKG20208.1 - 0.085 10.1 5.9 0.12 9.7 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.15 EKG20208.1 - 0.13 12.0 5.2 1.2 8.9 0.3 2.8 2 1 1 3 3 3 0 Prefoldin subunit IncA PF04156.9 EKG20208.1 - 0.22 11.0 4.8 0.44 10.1 3.4 1.4 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 EKG20208.1 - 0.23 11.2 2.8 16 5.3 0.0 2.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus KLRAQ PF10205.4 EKG20208.1 - 2 8.5 6.3 0.2 11.7 0.5 2.2 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.4 EKG20208.1 - 2 7.2 5.0 3.1 6.6 3.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Aldo_ket_red PF00248.16 EKG20209.1 - 2.8e-55 187.1 0.0 3.3e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 EKG20210.1 - 7e-22 77.2 0.0 1.5e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG20210.1 - 5.9e-18 64.3 0.0 1.7e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EKG20210.1 - 0.00025 21.3 0.0 0.043 14.0 0.0 2.6 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG20210.1 - 0.0074 16.7 0.0 0.12 12.7 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1768 PF08719.6 EKG20211.1 - 1.4e-51 174.3 2.5 1.6e-51 174.1 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RNase_T PF00929.19 EKG20212.1 - 8.5e-24 84.6 0.8 9.8e-24 84.4 0.5 1.0 1 0 0 1 1 1 1 Exonuclease DNA_pol_B PF00136.16 EKG20213.1 - 6.8e-113 377.8 0.8 6.8e-113 377.8 0.6 1.4 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EKG20213.1 - 3.5e-64 215.6 0.0 6.2e-64 214.8 0.0 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EKG20213.1 - 1.5e-38 132.5 0.0 4.6e-38 130.8 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EKG20213.1 - 4.4e-25 87.2 8.7 4.4e-25 87.2 6.0 2.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Sugar_tr PF00083.19 EKG20214.1 - 1.1e-93 314.3 17.8 1.2e-93 314.1 12.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20214.1 - 4.6e-22 78.1 16.4 4.6e-22 78.1 11.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EKG20214.1 - 0.12 12.3 3.3 1.3 9.0 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Glyco_hydro_32N PF00251.15 EKG20215.1 - 6.9e-34 117.5 0.0 9.4e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 EKG20215.1 - 5.5e-06 25.6 0.1 0.053 12.6 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 EKG20215.1 - 0.011 14.4 0.2 0.03 13.0 0.1 1.6 1 1 0 1 1 1 0 Levansucrase/Invertase Fungal_trans PF04082.13 EKG20216.1 - 1.4e-20 73.3 0.1 2.3e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG20216.1 - 1.7e-05 24.6 8.3 2.8e-05 23.9 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 EKG20216.1 - 1.1 8.9 7.3 2 8.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Glyco_hydro_2 PF00703.16 EKG20217.1 - 2.3e-05 24.7 0.0 5.9e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EKG20217.1 - 0.002 17.0 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DASH_Duo1 PF08651.5 EKG20218.1 - 3.7e-28 96.8 3.0 5e-28 96.4 2.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF745 PF05335.8 EKG20218.1 - 0.0041 16.6 4.9 0.0069 15.9 3.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF3407 PF11887.3 EKG20218.1 - 0.017 14.4 0.7 0.022 14.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) DASH_Dad1 PF08649.5 EKG20218.1 - 0.058 13.1 1.0 0.18 11.5 0.5 1.8 1 1 1 2 2 2 0 DASH complex subunit Dad1 DASH_Dad2 PF08654.5 EKG20218.1 - 0.47 10.4 5.6 4.4 7.3 3.8 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF3829 PF12889.2 EKG20218.1 - 1.4 8.0 4.8 0.42 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) ABC_tran PF00005.22 EKG20220.1 - 1.2e-34 119.5 0.0 2.4e-34 118.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EKG20220.1 - 4.4e-19 68.9 14.6 4.4e-19 68.9 10.1 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.1 EKG20220.1 - 0.00021 21.3 0.1 0.00067 19.6 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EKG20220.1 - 0.00025 20.3 0.2 0.042 13.0 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG20220.1 - 0.00027 21.0 0.0 0.019 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 EKG20220.1 - 0.0011 18.4 0.2 0.0043 16.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG20220.1 - 0.0016 18.6 0.3 0.0073 16.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EKG20220.1 - 0.0018 17.3 0.0 0.0039 16.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF258 PF03193.11 EKG20220.1 - 0.0059 15.8 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG20220.1 - 0.014 16.1 0.0 0.039 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EKG20220.1 - 0.016 15.5 0.0 0.051 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain Herpes_gE PF02480.11 EKG20220.1 - 0.069 11.3 0.1 0.26 9.4 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF87 PF01935.12 EKG20220.1 - 0.09 12.5 0.2 0.09 12.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 EKG20220.1 - 0.095 12.0 0.4 0.46 9.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EKG20220.1 - 0.46 10.2 2.3 0.3 10.8 0.1 1.9 2 0 0 2 2 1 0 Dynamin family SbcCD_C PF13558.1 EKG20220.1 - 0.57 10.1 3.6 0.83 9.6 0.1 3.0 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit GalKase_gal_bdg PF10509.4 EKG20221.1 - 4.6e-20 70.6 0.0 1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EKG20221.1 - 5.5e-16 58.5 0.1 3.5e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EKG20221.1 - 5.8e-15 55.1 3.7 6.3e-15 54.9 1.2 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain HTH_23 PF13384.1 EKG20221.1 - 0.025 14.2 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Glycos_transf_2 PF00535.21 EKG20223.1 - 9.4e-35 119.7 0.0 1.1e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EKG20223.1 - 1e-15 58.1 0.0 1.4e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EKG20223.1 - 2.4e-10 39.9 0.0 3.1e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EKG20223.1 - 1.1e-06 28.0 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EKG20223.1 - 0.0076 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 EKG20223.1 - 0.02 15.1 0.0 0.036 14.3 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 Cyclin_N PF00134.18 EKG20224.1 - 1.4e-16 60.2 0.9 2.8e-16 59.2 0.3 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EKG20224.1 - 0.0011 18.8 0.3 0.049 13.5 0.0 2.5 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EKG20224.1 - 0.0095 15.7 3.5 1.3 8.9 0.2 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat DUF3210 PF11489.3 EKG20226.1 - 1.7e-202 674.9 75.3 1.7e-202 674.9 52.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) Wound_ind PF08186.6 EKG20226.1 - 0.72 9.8 10.8 3 7.8 0.4 3.8 3 0 0 3 3 3 0 Wound-inducible basic protein family Cg6151-P PF10233.4 EKG20227.1 - 3.8e-31 107.4 10.3 4.5e-31 107.1 7.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Trep_Strep PF09605.5 EKG20227.1 - 2.2 7.9 15.3 0.12 11.9 1.9 2.2 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) NTF2 PF02136.15 EKG20228.1 - 1.8e-32 112.2 0.5 2e-32 112.0 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 EKG20228.1 - 0.11 12.6 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Epimerase PF01370.16 EKG20229.1 - 9.6e-18 64.4 0.0 1.5e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG20229.1 - 1.5e-11 43.5 0.0 2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG20229.1 - 2.4e-11 43.0 0.0 6.1e-10 38.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EKG20229.1 - 2.2e-08 34.3 0.1 4.4e-08 33.3 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EKG20229.1 - 4e-07 30.1 0.0 6.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EKG20229.1 - 0.00016 20.7 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EKG20229.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EKG20229.1 - 0.0053 16.0 0.2 0.012 14.9 0.1 1.7 2 1 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 EKG20229.1 - 0.0075 16.1 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EKG20229.1 - 0.037 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EKG20229.1 - 0.1 11.4 0.0 0.31 9.9 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain PFK PF00365.15 EKG20230.1 - 2e-163 542.1 0.7 2.4e-120 400.7 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF822 PF05687.8 EKG20231.1 - 0.72 10.2 5.3 1.3 9.4 3.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) ISN1 PF06437.6 EKG20232.1 - 9.1e-189 627.3 0.0 1e-188 627.1 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Med17 PF10156.4 EKG20233.1 - 1.1e-85 287.6 0.1 1.4e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex CENP-L PF13092.1 EKG20233.1 - 0.034 13.9 0.1 0.11 12.2 0.0 1.9 3 0 0 3 3 3 0 Kinetochore complex Sim4 subunit Fta1 4HBT PF03061.17 EKG20234.1 - 1.2e-12 47.7 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EKG20234.1 - 0.0077 16.2 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 EKG20234.1 - 0.071 12.8 0.0 0.082 12.6 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Tfb2 PF03849.9 EKG20235.1 - 1.5e-135 451.5 0.0 1.8e-135 451.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EKG20235.1 - 2.4e-06 27.3 0.0 5.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2373 PF10180.4 EKG20235.1 - 0.012 15.0 0.0 6.9 6.2 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2373) SinI PF08671.5 EKG20235.1 - 0.13 11.6 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Anti-repressor SinI ETF_QO PF05187.8 EKG20237.1 - 3.9e-46 155.5 0.0 6.4e-46 154.8 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EKG20237.1 - 1.9e-09 36.8 0.0 0.00021 20.3 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG20237.1 - 3.9e-07 29.2 0.1 0.0033 16.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG20237.1 - 1e-06 28.6 0.0 2.9e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG20237.1 - 6.5e-05 22.1 0.0 0.0033 16.5 0.1 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EKG20237.1 - 0.00015 21.0 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG20237.1 - 0.00016 21.6 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG20237.1 - 0.00019 20.0 0.2 0.00033 19.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EKG20237.1 - 0.00048 20.2 0.0 0.00095 19.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG20237.1 - 0.0013 18.5 0.1 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EKG20237.1 - 0.0015 18.9 0.0 6.1 7.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG20237.1 - 0.0015 17.6 0.1 0.0028 16.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.2 EKG20237.1 - 0.0025 18.1 1.6 0.0093 16.3 1.1 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.9 EKG20237.1 - 0.0034 16.0 0.1 0.046 12.3 0.0 2.4 3 0 0 3 3 3 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EKG20237.1 - 0.013 14.4 0.3 0.018 13.9 0.2 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EKG20237.1 - 0.11 11.3 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ADH_N PF08240.7 EKG20238.1 - 3.1e-29 100.9 2.7 5.3e-29 100.1 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG20238.1 - 3.4e-20 71.8 0.5 5.5e-20 71.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EKG20238.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EKG20238.1 - 0.074 12.9 0.2 0.099 12.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG20238.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EKG20238.1 - 0.16 11.4 3.1 0.66 9.5 0.1 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_trans_2_3 PF13632.1 EKG20239.1 - 2.9e-43 147.8 1.1 2.9e-43 147.8 0.7 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG20239.1 - 1.3e-07 31.7 0.0 3.8e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EKG20239.1 - 1.3e-05 24.9 0.0 0.00012 21.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EKG20239.1 - 0.028 13.7 0.0 0.083 12.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 21 DUF457 PF04307.9 EKG20239.1 - 6.4 6.0 12.2 1.7 7.9 0.0 3.2 3 1 0 3 3 3 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Chromo PF00385.19 EKG20240.1 - 0.029 14.0 13.2 0.051 13.2 2.8 2.4 1 1 1 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Nefa_Nip30_N PF10187.4 EKG20240.1 - 0.043 13.9 2.1 0.095 12.8 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4611 PF15387.1 EKG20240.1 - 0.16 12.1 4.2 0.34 11.0 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Bd3614_N PF14442.1 EKG20240.1 - 0.37 10.7 4.0 0.61 10.0 2.8 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal MFS_1 PF07690.11 EKG20241.1 - 8.4e-37 126.6 22.4 8.4e-37 126.6 15.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20241.1 - 2.4e-07 29.7 28.3 1.3e-06 27.2 19.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Bac_surface_Ag PF01103.18 EKG20242.1 - 4.9e-42 144.5 0.0 6.5e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.21 EKG20243.1 - 1.1e-25 89.6 0.0 1.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NADH_u_ox_C PF12853.2 EKG20244.1 - 5.3e-33 112.6 0.1 7.9e-33 112.0 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EKG20244.1 - 6.4e-33 112.8 0.3 1e-32 112.2 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit THRAP3_BCLAF1 PF15440.1 EKG20244.1 - 0.019 13.6 0.0 0.025 13.2 0.0 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family AAA_12 PF13087.1 EKG20245.1 - 3.9e-27 94.9 0.0 6.3e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG20245.1 - 4.5e-24 85.3 0.0 9.7e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG20245.1 - 2.9e-09 36.5 0.2 1.6e-08 34.1 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EKG20245.1 - 1e-06 28.4 0.0 0.00043 19.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EKG20245.1 - 0.00016 21.5 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EKG20245.1 - 0.0016 17.9 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EKG20245.1 - 0.0025 17.2 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG20245.1 - 0.003 17.6 0.0 0.0091 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EKG20245.1 - 0.0033 17.6 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG20245.1 - 0.0067 16.4 0.0 0.033 14.1 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EKG20245.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EKG20245.1 - 0.018 13.9 0.9 0.022 13.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EKG20245.1 - 0.026 14.0 0.2 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EKG20245.1 - 0.031 15.0 0.0 0.83 10.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 EKG20245.1 - 0.037 14.1 0.1 0.093 12.8 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EKG20245.1 - 0.042 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NB-ARC PF00931.17 EKG20245.1 - 0.048 12.5 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DnaB_C PF03796.10 EKG20245.1 - 0.053 12.4 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PhoH PF02562.11 EKG20245.1 - 0.081 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EKG20245.1 - 0.096 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 EKG20245.1 - 0.13 12.0 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EKG20245.1 - 0.21 11.7 0.0 0.59 10.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase UCH PF00443.24 EKG20246.1 - 1.9e-42 145.2 0.0 4.8e-36 124.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG20246.1 - 1.2e-11 44.6 0.1 1.8e-10 40.7 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L9_N PF01281.14 EKG20247.1 - 1e-09 37.4 0.0 2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EKG20247.1 - 0.00055 19.9 0.2 0.19 11.8 0.2 2.6 1 1 0 1 1 1 1 Ribosomal protein L9, C-terminal domain F_bP_aldolase PF01116.15 EKG20248.1 - 8.7e-101 336.7 0.0 9.8e-101 336.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II COP-gamma_platf PF08752.5 EKG20248.1 - 0.0041 16.9 0.0 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Peptidase_C26 PF07722.8 EKG20248.1 - 0.034 13.5 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase C26 DUF1806 PF08830.5 EKG20248.1 - 0.11 12.3 0.1 2.7 7.8 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1806) TRM PF02005.11 EKG20251.1 - 5.7e-22 78.1 0.0 1.2e-13 50.7 0.0 2.1 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase DUF2834 PF11196.3 EKG20252.1 - 0.011 15.8 1.9 0.011 15.8 1.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2834) ATG11 PF10377.4 EKG20253.1 - 1.1e-41 141.7 0.1 1.1e-41 141.7 0.1 3.5 4 1 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.7 EKG20253.1 - 6.3e-05 21.9 0.1 6.3e-05 21.9 0.1 5.4 4 1 0 5 5 5 1 Autophagy protein Apg17 ERM PF00769.14 EKG20253.1 - 0.0019 17.7 22.5 0.0019 17.7 15.6 7.4 6 2 2 8 8 8 2 Ezrin/radixin/moesin family Nup54 PF13874.1 EKG20253.1 - 0.0037 16.9 4.5 0.0037 16.9 3.1 7.2 5 1 4 9 9 9 1 Nucleoporin complex subunit 54 FAT PF02259.18 EKG20255.1 - 2.9e-122 408.0 0.2 2.9e-122 408.0 0.2 3.1 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.22 EKG20255.1 - 2e-62 210.7 0.5 4.3e-62 209.6 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EKG20255.1 - 7.8e-52 175.4 1.1 6.4e-50 169.2 0.0 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EKG20255.1 - 3.5e-43 145.7 2.3 2.8e-42 142.8 0.0 3.5 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EKG20255.1 - 1.8e-17 63.3 18.8 0.00013 22.2 0.0 8.6 7 2 0 7 7 7 4 HEAT repeats FATC PF02260.15 EKG20255.1 - 3.6e-17 61.4 0.1 8.5e-17 60.2 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EKG20255.1 - 9e-13 47.1 19.7 0.38 10.9 0.0 11.2 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 EKG20255.1 - 2.3e-08 34.2 20.4 0.081 13.4 0.0 11.3 10 1 2 12 12 12 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EKG20255.1 - 5.1e-06 26.7 0.0 0.38 11.1 0.0 6.2 6 1 1 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EKG20255.1 - 0.0034 16.7 3.8 2 7.7 0.0 4.8 6 0 0 6 6 6 2 CLASP N terminal TPR_16 PF13432.1 EKG20255.1 - 5.4 7.8 0.0 5.4 7.8 0.0 6.0 7 0 0 7 7 4 0 Tetratricopeptide repeat Surp PF01805.15 EKG20256.1 - 3.2e-17 61.9 0.0 5.8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 EKG20256.1 - 0.18 11.8 0.0 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ashwin PF15323.1 EKG20258.1 - 1.1 9.1 10.7 0.17 11.8 4.2 2.1 2 0 0 2 2 2 0 Developmental protein HAD_2 PF13419.1 EKG20259.1 - 0.00066 19.9 0.0 1.4 9.0 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG20259.1 - 0.0036 16.9 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like zf-PARP PF00645.13 EKG20260.1 - 2.1e-20 72.7 0.2 5.7e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CHZ PF09649.5 EKG20262.1 - 0.0073 15.5 1.8 0.014 14.5 1.2 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ Brix PF04427.13 EKG20263.1 - 1.2e-49 168.5 0.0 2.5e-49 167.5 0.0 1.5 1 1 0 1 1 1 1 Brix domain CAF-1_p150 PF11600.3 EKG20263.1 - 0.065 12.6 20.3 0.13 11.6 14.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BUD22 PF09073.5 EKG20263.1 - 1.8 7.5 28.6 3.5 6.5 12.3 2.4 2 1 0 2 2 2 0 BUD22 DEAD PF00270.24 EKG20264.1 - 7.5e-29 100.3 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG20264.1 - 8.8e-26 89.5 0.0 2.2e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain eIF-3c_N PF05470.7 EKG20265.1 - 5e-176 586.3 18.5 6.3e-144 480.2 0.7 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EKG20265.1 - 1.6e-14 54.0 0.1 5.9e-14 52.2 0.1 2.1 1 0 0 1 1 1 1 PCI domain CDC45 PF02724.9 EKG20265.1 - 1.7 6.5 14.9 2.6 5.9 10.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 EKG20265.1 - 3.3 5.8 11.1 6.7 4.8 7.7 1.5 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 EKG20265.1 - 3.3 7.0 20.0 6 6.1 12.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) EAP30 PF04157.11 EKG20266.1 - 1.6e-61 207.3 0.0 2.2e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_L30_N PF08079.7 EKG20267.1 - 8e-26 89.8 15.5 1.8e-25 88.7 10.8 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EKG20267.1 - 1.1e-19 69.7 3.8 1.3e-19 69.4 1.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Cyclin PF08613.6 EKG20268.1 - 4.2e-14 53.2 0.0 6.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EKG20268.1 - 0.0093 15.5 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF357 PF04010.8 EKG20269.1 - 0.038 13.6 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF357) CRC_subunit PF08624.5 EKG20272.1 - 5e-59 198.1 0.2 1.4e-58 196.7 0.0 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Pkinase PF00069.20 EKG20273.1 - 6.5e-71 238.5 0.0 8.7e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20273.1 - 8.3e-31 106.9 0.0 1.2e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EKG20273.1 - 1.8e-12 47.5 0.5 1.8e-12 47.5 0.3 2.5 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EKG20273.1 - 4.4e-09 35.7 0.0 2.2e-08 33.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EKG20273.1 - 0.0023 17.6 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EKG20273.1 - 0.039 13.3 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EKG20273.1 - 0.045 13.3 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EKG20273.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MaoC_dehydratas PF01575.14 EKG20274.1 - 3.7e-21 74.7 0.0 6.8e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EKG20274.1 - 5e-07 29.5 0.0 5.2e-05 23.0 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase HeLo PF14479.1 EKG20275.1 - 6.5e-20 71.7 1.1 1.3e-19 70.8 0.8 1.5 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 EKG20275.1 - 0.00011 21.4 0.0 0.0012 18.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20275.1 - 0.00072 18.7 0.0 0.25 10.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Profilin PF00235.14 EKG20276.1 - 1.1e-42 144.9 0.6 1.2e-42 144.8 0.4 1.0 1 0 0 1 1 1 1 Profilin CHASE4 PF05228.8 EKG20276.1 - 0.051 13.1 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 CHASE4 domain GP4 PF03010.9 EKG20276.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 GP4 UQ_con PF00179.21 EKG20277.1 - 3.4e-35 120.4 0.2 3.8e-35 120.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG20277.1 - 0.00062 19.5 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKG20277.1 - 0.0047 16.7 0.0 0.0054 16.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EKG20277.1 - 0.018 14.7 0.2 0.023 14.3 0.1 1.2 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.13 EKG20278.1 - 1.9e-35 122.2 0.1 5e-34 117.6 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Viral_cys_rich PF08008.7 EKG20278.1 - 0.19 11.3 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 Viral cysteine rich NCA2 PF08637.5 EKG20279.1 - 5e-86 288.1 0.1 7.8e-86 287.5 0.1 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Ras PF00071.17 EKG20280.1 - 3.9e-65 218.1 0.0 4.7e-65 217.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG20280.1 - 1.7e-19 70.5 0.0 2.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG20280.1 - 3.7e-13 49.0 0.0 4.5e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EKG20280.1 - 3.4e-06 26.6 0.0 5.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKG20280.1 - 5.9e-06 25.5 0.0 7.5e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EKG20280.1 - 0.0048 16.8 0.0 0.0071 16.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EKG20280.1 - 0.032 13.4 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EKG20280.1 - 0.047 12.9 0.0 0.22 10.8 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 EKG20280.1 - 0.06 13.5 0.0 5.3 7.2 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EKG20280.1 - 0.078 12.1 0.0 0.22 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EKG20280.1 - 0.1 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG20280.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 EKG20280.1 - 0.26 9.9 0.9 16 4.0 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Ferritin_2 PF13668.1 EKG20281.1 - 1.3e-20 73.7 0.0 1.9e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain MiaE_2 PF13794.1 EKG20281.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like MFS_1 PF07690.11 EKG20282.1 - 5.6e-33 114.1 67.7 1.7e-26 92.7 27.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tom5 PF10642.4 EKG20282.1 - 0.037 13.6 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Pkinase PF00069.20 EKG20283.1 - 2e-52 177.9 0.0 4.6e-52 176.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20283.1 - 1.4e-23 83.3 0.0 3.3e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG20283.1 - 0.00026 20.8 2.8 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EKG20283.1 - 0.0073 15.6 0.1 0.027 13.7 0.1 1.8 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EKG20283.1 - 0.043 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) DUF904 PF06005.7 EKG20285.1 - 0.01 16.1 2.9 0.01 16.1 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Complex1_49kDa PF00346.14 EKG20285.1 - 0.05 12.6 0.1 0.073 12.0 0.1 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NYD-SP28_assoc PF14775.1 EKG20285.1 - 0.16 11.7 4.3 0.66 9.7 1.2 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain Cep57_CLD_2 PF14197.1 EKG20285.1 - 3.8 7.5 12.3 0.24 11.3 2.8 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 LRR_4 PF12799.2 EKG20286.1 - 1.4e-37 126.7 40.9 2.6e-08 33.2 0.7 11.0 5 3 6 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG20286.1 - 1e-30 105.2 34.1 2.3e-09 36.8 1.3 8.4 5 2 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 EKG20286.1 - 8.7e-17 58.5 34.8 0.23 11.5 0.1 15.4 16 2 1 17 17 17 7 Leucine Rich Repeat LRR_7 PF13504.1 EKG20286.1 - 5.9e-13 46.7 35.5 0.12 12.6 0.1 13.8 15 0 0 15 15 15 5 Leucine rich repeat LRR_6 PF13516.1 EKG20286.1 - 1.7e-07 30.6 30.0 0.041 13.9 0.2 11.4 10 2 1 11 11 11 3 Leucine Rich repeat DUF4223 PF13978.1 EKG20287.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Fasciclin PF02469.17 EKG20288.1 - 8.8e-51 171.2 6.5 2e-28 98.9 1.2 2.2 2 0 0 2 2 2 2 Fasciclin domain Cation_efflux PF01545.16 EKG20289.1 - 6.9e-29 100.8 4.4 9.2e-29 100.3 3.1 1.1 1 0 0 1 1 1 1 Cation efflux family FA_desaturase PF00487.19 EKG20290.1 - 0.028 13.8 1.9 0.056 12.8 1.3 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DUF2956 PF11169.3 EKG20290.1 - 3.9 7.4 5.8 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Acetyltransf_1 PF00583.19 EKG20291.1 - 0.042 13.8 0.1 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Aldo_ket_red PF00248.16 EKG20292.1 - 1.8e-59 200.8 0.0 2.1e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lipid_bd PF12888.2 EKG20292.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipid-binding putative hydrolase HET PF06985.6 EKG20293.1 - 0.0081 16.3 0.1 0.017 15.2 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EKG20294.1 - 1.4e-05 25.3 1.3 2.7e-05 24.3 0.9 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3433 PF11915.3 EKG20296.1 - 4.7e-20 71.5 2.4 3.3e-13 49.5 0.0 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) p450 PF00067.17 EKG20298.1 - 8.6e-59 199.2 0.0 1e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAT PF03417.11 EKG20299.1 - 0.034 13.6 0.1 0.36 10.2 0.0 2.5 3 0 0 3 3 3 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TIMELESS PF04821.9 EKG20301.1 - 3.5e-86 288.7 0.2 3.5e-86 288.7 0.2 2.4 4 0 0 4 4 4 1 Timeless protein TIMELESS_C PF05029.8 EKG20301.1 - 3.1e-28 99.0 46.0 1.2e-26 93.7 0.0 4.2 2 1 1 4 4 4 3 Timeless protein C terminal region 3HCDH_N PF02737.13 EKG20302.1 - 2.6e-52 177.0 0.9 3.4e-52 176.7 0.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EKG20302.1 - 3.6e-34 117.0 0.0 8.9e-34 115.7 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EKG20302.1 - 0.00039 20.2 0.5 0.0011 18.8 0.3 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EKG20302.1 - 0.0016 17.8 0.5 0.0079 15.6 0.1 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EKG20302.1 - 0.0027 17.4 0.2 0.0043 16.7 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EKG20302.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EKG20302.1 - 0.018 15.4 0.7 0.055 13.8 0.5 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 EKG20302.1 - 0.051 13.6 0.6 0.16 12.0 0.4 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EKG20302.1 - 0.064 12.4 0.3 0.15 11.2 0.2 1.8 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EKG20302.1 - 0.15 10.9 0.3 0.32 9.8 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Vps35 PF03635.12 EKG20304.1 - 0 1039.9 0.0 0 1039.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Arylsulfotran_2 PF14269.1 EKG20306.1 - 0.0031 16.7 0.0 0.0052 15.9 0.0 1.4 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Cyclin_C PF02984.14 EKG20308.1 - 0.013 15.4 0.1 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain Chitin_bind_3 PF03067.10 EKG20309.1 - 1.2e-12 48.5 2.3 1.3e-12 48.3 1.6 1.1 1 0 0 1 1 1 1 Chitin binding domain Fringe PF02434.11 EKG20310.1 - 0.027 13.6 0.1 0.43 9.7 0.1 2.5 2 1 0 2 2 2 0 Fringe-like NPP1 PF05630.6 EKG20311.1 - 3.4e-53 180.4 0.1 4.2e-53 180.1 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) TauD PF02668.11 EKG20312.1 - 2.5e-41 142.0 0.0 3.4e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EKG20312.1 - 1.9e-07 31.4 0.0 5e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.5 EKG20312.1 - 0.081 11.8 0.0 0.34 9.7 0.0 1.8 1 1 0 1 1 1 0 CsiD AAA PF00004.24 EKG20313.1 - 1.7e-40 138.2 0.0 3.9e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG20313.1 - 0.00011 21.8 0.1 0.00057 19.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EKG20313.1 - 0.00014 21.0 0.0 0.0005 19.1 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EKG20313.1 - 0.00024 21.1 0.1 0.013 15.5 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EKG20313.1 - 0.0008 19.5 1.1 0.018 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.9 EKG20313.1 - 0.0018 18.1 0.5 0.0095 15.8 0.0 2.3 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EKG20313.1 - 0.003 16.8 0.2 0.045 12.9 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EKG20313.1 - 0.0057 15.8 0.1 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EKG20313.1 - 0.0074 16.1 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EKG20313.1 - 0.011 14.6 0.7 0.019 13.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 EKG20313.1 - 0.017 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EKG20313.1 - 0.024 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EKG20313.1 - 0.035 13.5 1.1 0.35 10.2 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EKG20313.1 - 0.049 13.2 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EKG20313.1 - 0.056 12.5 0.8 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 EKG20313.1 - 0.059 12.9 0.1 0.51 9.8 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EKG20313.1 - 0.086 12.7 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EKG20313.1 - 0.1 13.3 0.1 0.1 13.3 0.1 2.9 2 2 0 2 2 2 0 AAA domain DUF3419 PF11899.3 EKG20314.1 - 8e-143 475.7 0.4 9.2e-108 360.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EKG20314.1 - 6.9e-10 38.8 0.0 1.9e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG20314.1 - 1.8e-07 31.6 0.0 1.3e-06 28.9 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG20314.1 - 2.4e-06 27.5 0.5 0.00019 21.4 0.0 3.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG20314.1 - 2.8e-06 27.0 0.0 9.1e-06 25.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG20314.1 - 1.5e-05 25.3 0.0 8e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG20314.1 - 0.00047 20.6 0.0 0.018 15.5 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 EKG20314.1 - 0.0051 16.3 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EKG20314.1 - 0.013 14.6 0.0 0.079 12.0 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Rer1 PF03248.8 EKG20315.1 - 1.4e-79 265.8 3.9 1.5e-79 265.6 2.7 1.0 1 0 0 1 1 1 1 Rer1 family UbiA PF01040.13 EKG20315.1 - 0.0025 17.0 3.5 0.004 16.4 2.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family ECH PF00378.15 EKG20316.1 - 3.3e-68 229.4 0.1 3.8e-68 229.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EKG20316.1 - 0.0028 17.4 0.2 0.22 11.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Peptidase_C8 PF03569.8 EKG20316.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C8 Tape_meas_lam_C PF09718.5 EKG20317.1 - 0.11 12.4 0.5 3 7.8 0.1 2.1 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Glycoprotein_B PF00606.13 EKG20317.1 - 1.3 6.9 4.9 2 6.3 3.3 1.3 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B Antimicrobial_2 PF08023.7 EKG20317.1 - 2.4 8.5 6.1 13 6.2 0.6 3.1 2 1 0 2 2 2 0 Frog antimicrobial peptide MIF4G PF02854.14 EKG20318.1 - 4.2e-49 166.7 0.1 4.2e-49 166.7 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 EKG20318.1 - 1.7e-17 63.0 0.1 9.2e-17 60.7 0.0 2.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Homeobox PF00046.24 EKG20319.1 - 5.3e-17 61.1 0.6 1.1e-16 60.1 0.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EKG20319.1 - 0.013 15.2 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain efThoc1 PF11957.3 EKG20320.1 - 8.2e-146 486.3 0.1 1.1e-145 485.9 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Swi3 PF07962.7 EKG20321.1 - 4.2e-30 103.2 0.2 9.2e-30 102.1 0.1 1.6 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DSHCT PF08148.7 EKG20322.1 - 4.9e-61 205.1 0.5 1e-60 204.0 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EKG20322.1 - 1.2e-19 70.4 0.0 2.8e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG20322.1 - 1.4e-06 28.0 0.0 4.1e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG20322.1 - 0.0058 16.4 0.2 0.21 11.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Cse1 PF08506.5 EKG20323.1 - 8.5e-10 37.7 1.1 4.2e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 Cse1 DUF2435 PF10363.4 EKG20323.1 - 4.8e-05 23.1 0.3 0.0069 16.2 0.3 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Xpo1 PF08389.7 EKG20323.1 - 0.0011 18.8 4.7 0.67 9.8 0.0 5.0 6 0 0 6 6 6 2 Exportin 1-like protein XkdW PF09636.5 EKG20324.1 - 0.031 14.1 0.1 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 XkdW protein AAA_11 PF13086.1 EKG20325.1 - 1.2e-60 205.0 0.8 4.2e-60 203.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EKG20325.1 - 8.4e-59 198.3 0.0 7.5e-58 195.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG20325.1 - 5.1e-13 48.5 0.2 1.4e-11 43.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EKG20325.1 - 1.3e-11 44.4 0.1 9.7e-10 38.3 0.0 3.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EKG20325.1 - 2e-07 30.3 1.1 1.7e-06 27.2 0.8 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EKG20325.1 - 2.4e-07 30.5 0.1 0.043 13.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EKG20325.1 - 4.3e-07 29.9 0.0 1.5e-06 28.2 0.0 1.9 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EKG20325.1 - 4.1e-06 26.3 0.0 1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EKG20325.1 - 6.2e-05 23.1 0.2 0.0015 18.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EKG20325.1 - 0.00016 21.3 0.0 0.43 10.2 0.0 3.3 3 1 0 3 3 3 1 Helicase UvrD_C PF13361.1 EKG20325.1 - 0.00024 20.6 0.1 0.66 9.3 0.0 3.2 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain FtsK_SpoIIIE PF01580.13 EKG20325.1 - 0.0005 19.6 0.2 0.0051 16.3 0.0 2.5 3 0 0 3 3 3 1 FtsK/SpoIIIE family PhoH PF02562.11 EKG20325.1 - 0.00084 18.6 0.0 0.055 12.7 0.0 2.6 2 1 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EKG20325.1 - 0.0025 17.8 0.4 0.01 15.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EKG20325.1 - 0.0037 16.6 0.1 0.022 14.1 0.0 2.2 1 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EKG20325.1 - 0.0043 15.9 0.0 0.0081 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EKG20325.1 - 0.02 14.6 0.0 0.098 12.4 0.0 2.2 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA PF00004.24 EKG20325.1 - 0.022 14.9 0.3 0.093 12.9 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EKG20325.1 - 0.023 14.4 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zot PF05707.7 EKG20325.1 - 0.024 14.0 0.0 0.067 12.6 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EKG20325.1 - 0.025 14.0 0.0 0.17 11.2 0.0 2.0 1 1 1 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EKG20325.1 - 0.029 13.7 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD_C_2 PF13538.1 EKG20325.1 - 0.034 14.2 0.1 2 8.5 0.0 2.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EKG20325.1 - 0.05 12.5 0.0 7.5 5.3 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_33 PF13671.1 EKG20325.1 - 0.082 12.7 0.0 0.27 11.1 0.0 2.0 2 1 0 2 2 1 0 AAA domain 4HB_MCP_1 PF12729.2 EKG20325.1 - 0.24 10.7 2.0 0.19 11.0 0.2 1.6 2 0 0 2 2 1 0 Four helix bundle sensory module for signal transduction HhH-GPD PF00730.20 EKG20326.1 - 8.4e-22 77.5 0.0 1.8e-21 76.4 0.0 1.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EKG20326.1 - 7.8e-09 34.7 0.0 2.2e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif p450 PF00067.17 EKG20328.1 - 1.9e-62 211.3 0.0 1.6e-48 165.4 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 TFR_dimer PF04253.10 EKG20331.1 - 2.7e-25 88.3 0.0 5e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EKG20331.1 - 1.4e-12 47.7 0.0 2.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EKG20331.1 - 8.4e-08 31.8 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EKG20331.1 - 1.4e-05 24.6 0.0 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TadE PF07811.7 EKG20331.1 - 0.2 11.5 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 TadE-like protein RRM_1 PF00076.17 EKG20332.1 - 1.8e-09 37.1 0.0 2.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG20332.1 - 2e-06 27.6 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG20332.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 EKG20333.1 - 1.5e-59 201.2 0.1 2.4e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EKG20333.1 - 7.1e-30 103.3 0.2 1e-28 99.5 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.20 EKG20333.1 - 5.5e-14 52.4 0.0 2.2e-13 50.4 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG20333.1 - 1.9e-05 24.4 0.1 7.1e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EKG20333.1 - 0.029 13.7 0.1 0.2 11.0 0.1 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EKG20334.1 - 2.6e-40 138.2 37.9 2.4e-38 131.7 16.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Adeno_E3_CR2 PF02439.10 EKG20334.1 - 0.013 15.0 0.3 0.013 15.0 0.2 3.6 3 0 0 3 3 3 0 Adenovirus E3 region protein CR2 ESSS PF10183.4 EKG20334.1 - 0.015 15.6 0.6 15 6.0 0.0 3.4 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ASFV_J13L PF05568.6 EKG20334.1 - 0.021 14.3 1.6 0.18 11.3 0.1 2.7 3 0 0 3 3 3 0 African swine fever virus J13L protein EXS PF03124.9 EKG20334.1 - 0.13 11.2 5.3 0.046 12.7 1.0 2.1 2 1 0 2 2 2 0 EXS family DUF202 PF02656.10 EKG20334.1 - 1.2 9.3 9.1 2.6 8.3 3.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) F-box PF00646.28 EKG20335.1 - 5.4e-05 22.7 4.0 7.6e-05 22.2 0.3 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EKG20335.1 - 0.00044 19.9 2.0 0.0013 18.4 1.4 1.8 1 0 0 1 1 1 1 F-box-like Reo_sigmaC PF04582.7 EKG20336.1 - 0.0072 15.5 0.5 0.0097 15.1 0.4 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Herpes_capsid PF06112.6 EKG20336.1 - 8.5 6.4 11.3 15 5.6 7.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribonuc_L-PSP PF01042.16 EKG20337.1 - 3.8e-14 52.5 0.0 4.4e-14 52.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 EKG20338.1 - 4.7e-12 45.3 0.0 1.5e-11 43.6 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG20338.1 - 0.00029 20.6 11.5 0.00056 19.7 1.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EKG20340.1 - 0 1127.8 0.0 6.2e-90 301.5 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EKG20340.1 - 1.2e-189 628.4 0.0 2.3e-38 131.7 0.0 7.3 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EKG20340.1 - 3.4e-57 190.6 9.1 3.9e-10 39.8 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EKG20340.1 - 2.4e-26 92.4 1.2 6.5e-05 23.7 0.0 5.5 5 0 0 5 5 5 4 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EKG20340.1 - 7.7e-05 21.3 0.0 0.048 12.1 0.0 4.3 5 0 0 5 5 5 1 Transferase family WES_acyltransf PF03007.11 EKG20340.1 - 0.0011 18.6 0.0 1.2 8.5 0.0 3.7 3 0 0 3 3 3 1 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF3245 PF11595.3 EKG20340.1 - 0.12 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) AATase PF07247.7 EKG20340.1 - 0.16 10.4 0.1 8.1 4.8 0.0 3.3 4 0 0 4 4 4 0 Alcohol acetyltransferase DUF943 PF06092.7 EKG20340.1 - 2 7.6 0.0 4 6.7 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) ABC_membrane PF00664.18 EKG20341.1 - 1.4e-72 244.4 23.8 1.6e-37 129.4 6.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EKG20341.1 - 1.8e-66 222.6 0.0 6.7e-33 113.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKG20341.1 - 7.8e-12 44.8 0.0 0.00058 19.1 0.0 3.5 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG20341.1 - 3e-06 27.4 0.3 0.32 10.9 0.1 4.0 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EKG20341.1 - 8.8e-06 25.1 0.3 0.1 12.1 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EKG20341.1 - 0.00013 21.8 2.9 0.17 11.8 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EKG20341.1 - 0.00019 20.6 0.0 0.089 11.9 0.0 2.7 3 0 0 3 3 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EKG20341.1 - 0.00072 20.3 0.1 0.067 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EKG20341.1 - 0.00088 17.9 0.0 0.19 10.2 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.1 EKG20341.1 - 0.0017 18.5 0.1 2.7 8.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EKG20341.1 - 0.0018 17.9 0.3 6.7 6.2 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EKG20341.1 - 0.0035 16.7 0.0 1.1 8.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EKG20341.1 - 0.0039 16.3 0.1 1.2 8.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 EKG20341.1 - 0.0064 16.8 0.1 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EKG20341.1 - 0.0074 16.0 0.1 1.4 8.6 0.0 3.4 4 0 0 4 4 4 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EKG20341.1 - 0.0086 16.0 3.3 2.7 7.9 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.12 EKG20341.1 - 0.015 15.1 0.3 0.49 10.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_33 PF13671.1 EKG20341.1 - 0.018 14.9 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EKG20341.1 - 0.064 12.9 0.1 6 6.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_10 PF12846.2 EKG20341.1 - 0.068 12.5 0.6 7.5 5.8 0.2 2.5 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EKG20341.1 - 0.074 13.0 0.4 14 5.6 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EKG20341.1 - 0.16 12.3 0.0 0.76 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain K_oxygenase PF13434.1 EKG20342.1 - 8.7e-103 343.8 0.0 1.3e-102 343.2 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EKG20342.1 - 9e-11 41.7 0.1 1.9e-08 34.2 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG20342.1 - 8e-10 39.1 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG20342.1 - 4.4e-06 26.7 0.0 6e-05 23.0 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 EKG20342.1 - 0.024 13.7 0.0 0.68 8.9 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) Herpes_BBRF1 PF04793.7 EKG20342.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 BRRF1-like protein PGM_PMM_I PF02878.11 EKG20343.1 - 1.3e-32 112.2 0.0 1.9e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EKG20343.1 - 1e-24 86.7 0.0 1.8e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EKG20343.1 - 2.4e-14 53.5 0.1 5.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EKG20343.1 - 6.2e-12 45.3 0.1 1.6e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Oxysterol_BP PF01237.13 EKG20344.1 - 1.1e-92 310.2 0.3 1.4e-92 309.9 0.2 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Not1 PF04054.10 EKG20345.1 - 1.5e-128 428.9 0.0 4.7e-128 427.2 0.0 1.9 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EKG20345.1 - 1.5e-47 160.9 1.6 1.5e-47 160.9 1.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) FCH PF00611.18 EKG20346.1 - 1.6e-20 73.0 0.0 6.1e-20 71.2 0.0 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EKG20346.1 - 7.2e-14 50.9 0.0 1.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG20346.1 - 1.9e-12 46.5 0.0 3.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKG20346.1 - 3e-12 45.8 0.0 8.9e-12 44.3 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain DUF3947 PF13135.1 EKG20346.1 - 1.4 9.1 12.6 0.19 11.9 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) CFEM PF05730.6 EKG20348.1 - 1.8e-06 27.6 4.0 1.8e-06 27.6 2.8 3.2 3 0 0 3 3 3 1 CFEM domain Pkinase PF00069.20 EKG20349.1 - 1.8e-65 220.6 0.0 2.4e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20349.1 - 5.2e-30 104.3 0.0 7.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG20349.1 - 0.013 15.2 0.4 0.56 9.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG20349.1 - 0.017 14.0 0.0 0.069 12.0 0.0 1.9 1 1 1 2 2 2 0 Kinase-like Pkinase_C PF00433.19 EKG20349.1 - 0.029 14.8 0.0 0.13 12.7 0.0 2.2 1 0 0 1 1 1 0 Protein kinase C terminal domain DUF2968 PF11180.3 EKG20349.1 - 0.051 12.9 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Solute_trans_a PF03619.11 EKG20350.1 - 4.6e-82 275.4 20.9 5.4e-82 275.1 14.5 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Nodulin_late PF07127.6 EKG20350.1 - 4.8 7.3 6.4 7 6.8 0.1 3.0 2 0 0 2 2 2 0 Late nodulin protein TRM PF02005.11 EKG20353.1 - 2.3e-73 247.2 0.0 2.9e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EKG20353.1 - 0.00047 19.8 0.0 0.00083 18.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Menin PF05053.8 EKG20353.1 - 0.021 13.0 5.4 0.027 12.6 3.8 1.1 1 0 0 1 1 1 0 Menin TMEMspv1-c74-12 PF11044.3 EKG20353.1 - 0.55 9.8 1.7 1 8.9 1.2 1.4 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Hydrolase_6 PF13344.1 EKG20355.1 - 4e-23 81.2 0.0 7.9e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG20355.1 - 1.6e-12 46.9 0.0 1.7e-11 43.6 0.0 2.7 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EKG20355.1 - 0.0062 16.7 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase LexA_DNA_bind PF01726.11 EKG20356.1 - 0.0064 16.0 0.3 3 7.4 0.2 2.6 2 0 0 2 2 2 2 LexA DNA binding domain PI-PLC-X PF00388.14 EKG20358.1 - 2.6e-62 208.5 0.1 5.8e-62 207.4 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EKG20358.1 - 4.9e-38 129.7 0.0 1.2e-37 128.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EKG20358.1 - 0.00025 20.9 0.0 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like G6B PF15096.1 EKG20358.1 - 0.0076 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 G6B family GDPD PF03009.12 EKG20358.1 - 0.022 14.2 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Brix PF04427.13 EKG20359.1 - 8.2e-48 162.5 0.0 1e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 EKG20360.1 - 6.3e-74 246.6 2.4 6.3e-74 246.6 1.7 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EKG20360.1 - 2.9e-60 203.0 0.0 5.2e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG20360.1 - 4.1e-57 193.4 0.9 6.1e-57 192.9 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG20360.1 - 2.5e-14 52.7 0.4 6.9e-14 51.3 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EKG20360.1 - 4.5e-12 45.9 0.2 8e-11 41.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EKG20360.1 - 2.4e-07 30.7 0.0 4.8e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EKG20360.1 - 4.2e-05 23.1 0.1 0.47 9.9 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EKG20360.1 - 0.00077 18.5 0.8 0.0058 15.6 0.0 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EKG20360.1 - 0.00097 18.8 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EKG20360.1 - 0.002 17.1 0.1 0.44 9.4 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase UvrD-helicase PF00580.16 EKG20360.1 - 0.0022 17.3 0.0 0.026 13.8 0.0 2.2 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EKG20360.1 - 0.011 15.2 0.2 0.024 14.1 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 EKG20360.1 - 0.046 13.6 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EKG20360.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EKG20360.1 - 0.053 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 EKG20360.1 - 0.08 13.0 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EKG20360.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EKG20360.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EKG20360.1 - 0.15 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_S27e PF01667.12 EKG20360.1 - 0.42 10.1 3.8 0.5 9.9 0.7 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 BRCT PF00533.21 EKG20361.1 - 3.6e-06 27.0 0.0 0.09 12.9 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain ABM PF03992.11 EKG20362.1 - 1.4e-06 28.2 0.2 2.2e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase YjeF_N PF03853.10 EKG20363.1 - 1.5e-36 125.5 0.1 2.4e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EKG20363.1 - 9.6e-09 35.7 1.4 9.6e-09 35.7 1.0 2.0 2 0 0 2 2 2 1 FDF domain LysM PF01476.15 EKG20364.1 - 1e-06 28.4 0.0 2.8e-05 23.9 0.0 2.3 2 0 0 2 2 2 1 LysM domain HTH_Tnp_1 PF01527.15 EKG20364.1 - 0.077 12.9 0.0 8.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Transposase Tannase PF07519.6 EKG20365.1 - 9.1e-84 281.8 0.0 2.1e-83 280.6 0.0 1.5 1 1 0 1 1 1 1 Tannase and feruloyl esterase Rhomboid PF01694.17 EKG20366.1 - 4.6e-39 133.7 9.7 4.6e-39 133.7 6.7 2.5 3 0 0 3 3 3 1 Rhomboid family Wzy_C PF04932.10 EKG20366.1 - 0.51 10.1 4.7 4.8 6.9 0.2 2.4 2 0 0 2 2 2 0 O-Antigen ligase DUF843 PF05814.6 EKG20366.1 - 4.2 7.2 5.4 6.1 6.7 0.4 2.3 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Transp_cyt_pur PF02133.10 EKG20367.1 - 1.7e-86 290.4 36.4 2.2e-86 290.1 25.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 EKG20368.1 - 4.5e-24 85.2 0.0 1e-23 84.0 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG20368.1 - 2.1e-20 72.8 0.0 3.2e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EKG20369.1 - 0.039 12.6 8.4 0.01 14.5 3.8 1.5 2 0 0 2 2 2 0 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20370.1 - 6.4e-111 371.0 25.4 7.5e-111 370.8 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20370.1 - 5.3e-29 101.0 28.4 1.7e-27 96.0 13.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EKG20370.1 - 2.2 8.2 7.6 0.53 10.2 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) adh_short PF00106.20 EKG20371.1 - 1.7e-19 70.3 0.6 2.9e-19 69.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG20371.1 - 1.4e-06 28.2 0.0 4.4e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG20371.1 - 5.5e-06 26.1 0.3 8.2e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EKG20371.1 - 0.0011 18.4 0.1 0.0019 17.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PI3_PI4_kinase PF00454.22 EKG20372.1 - 0.012 15.1 0.4 0.059 12.8 0.3 2.1 1 1 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Rad4 PF03835.10 EKG20373.1 - 8.9e-13 47.8 1.6 1.7e-12 46.9 1.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EKG20373.1 - 3.9e-09 36.6 2.6 9.8e-09 35.4 1.8 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily OST-HTH PF12872.2 EKG20373.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Peptidase_C62 PF12380.3 EKG20373.1 - 0.19 10.5 0.2 0.34 9.6 0.1 1.3 1 0 0 1 1 1 0 Gill-associated viral 3C-like peptidase Fungal_trans PF04082.13 EKG20374.1 - 1.4e-08 33.9 0.0 2.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain UDP-g_GGTase PF06427.6 EKG20374.1 - 0.15 11.3 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose:Glycoprotein Glucosyltransferase adh_short PF00106.20 EKG20376.1 - 2.5e-27 95.8 0.1 3.2e-27 95.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG20376.1 - 2e-25 89.9 0.0 2.5e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG20376.1 - 5.4e-12 45.7 0.1 7.7e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG20376.1 - 0.0037 16.7 0.1 0.048 13.0 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EKG20376.1 - 0.017 14.9 1.0 0.051 13.4 0.4 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 EKG20376.1 - 0.087 11.9 0.2 0.22 10.5 0.1 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CABS1 PF15367.1 EKG20376.1 - 0.098 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 SurE PF01975.12 EKG20377.1 - 4.5e-44 150.1 0.0 6.2e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE His_Phos_2 PF00328.17 EKG20378.1 - 3.2e-22 79.3 0.0 4.1e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EKG20378.1 - 0.0003 20.9 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PhyH PF05721.8 EKG20379.1 - 3.3e-22 79.5 0.2 4.8e-22 79.0 0.2 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EKG20379.1 - 0.039 12.4 0.0 0.053 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Polyketide_cyc2 PF10604.4 EKG20379.1 - 0.084 13.0 0.0 10 6.2 0.0 2.4 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport ApbA_C PF08546.6 EKG20380.1 - 4e-28 97.9 0.0 5.2e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Amino_oxidase PF01593.19 EKG20381.1 - 8.9e-47 160.1 0.7 1.1e-46 159.8 0.5 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKG20381.1 - 2.3e-13 49.9 1.4 4e-13 49.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG20381.1 - 3.9e-09 35.8 1.3 1.7e-07 30.4 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG20381.1 - 9.2e-08 31.3 3.1 3e-06 26.3 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EKG20381.1 - 3.7e-07 30.4 0.3 4.7e-05 23.5 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG20381.1 - 8.7e-07 28.3 0.1 1.3e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG20381.1 - 5.9e-06 25.0 0.1 1.7e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EKG20381.1 - 2.6e-05 23.4 0.2 4.9e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EKG20381.1 - 9.1e-05 21.5 0.2 0.0034 16.3 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EKG20381.1 - 0.00054 18.9 0.3 0.00094 18.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EKG20381.1 - 0.00061 19.7 0.1 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG20381.1 - 0.00084 19.7 0.1 0.0032 17.8 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG20381.1 - 0.019 14.0 0.2 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain SNARE_assoc PF09335.6 EKG20383.1 - 0.048 13.8 0.8 0.11 12.6 0.1 1.8 2 0 0 2 2 2 0 SNARE associated Golgi protein ADH_zinc_N_2 PF13602.1 EKG20385.1 - 0.00025 21.9 0.4 0.0025 18.6 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Pkinase PF00069.20 EKG20386.1 - 4.5e-34 117.7 0.1 5.9e-34 117.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20386.1 - 1.4e-21 76.7 0.0 1.8e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKG20386.1 - 0.0051 15.9 0.3 0.013 14.5 0.1 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family HAD_2 PF13419.1 EKG20388.1 - 4.2e-32 111.7 0.0 5.9e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG20388.1 - 0.005 17.2 0.0 0.0086 16.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Kinetochor_Ybp2 PF08568.5 EKG20389.1 - 2.8e-130 435.5 0.0 3.3e-130 435.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin LSM PF01423.17 EKG20390.1 - 7.9e-18 63.7 0.2 1.1e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain Cyclin_N PF00134.18 EKG20391.1 - 2.8e-43 146.5 0.1 7e-43 145.2 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EKG20391.1 - 2.1e-32 111.5 0.0 4.6e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EKG20392.1 - 0.00022 21.0 11.5 0.00042 20.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EKG20392.1 - 0.0017 17.5 0.7 0.006 15.7 0.5 1.9 1 0 0 1 1 1 1 Histone chaperone domain CHZ Transglut_core PF01841.14 EKG20393.1 - 4.5e-11 42.9 0.0 8.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EKG20393.1 - 0.27 10.4 0.0 1.8 7.8 0.0 2.0 1 1 0 1 1 1 0 Transglutaminase-like domain DSBA PF01323.15 EKG20395.1 - 1.2e-23 83.7 0.1 1.3e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EKG20395.1 - 0.0079 16.2 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin NAD_binding_4 PF07993.7 EKG20396.1 - 0.0013 17.6 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EKG20396.1 - 0.0059 16.0 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG20396.1 - 0.014 14.0 0.0 0.026 13.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F-box-like PF12937.2 EKG20397.1 - 0.011 15.4 1.4 0.041 13.6 1.0 2.1 1 0 0 1 1 1 0 F-box-like GDPD PF03009.12 EKG20398.1 - 2.7e-30 105.7 0.0 7.2e-30 104.3 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EKG20398.1 - 0.0057 16.8 1.3 0.029 14.5 0.9 2.2 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF1371 PF07115.6 EKG20399.1 - 0.0083 16.2 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1371) DUF2982 PF11201.3 EKG20399.1 - 0.072 12.4 3.9 0.12 11.6 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2982) RNA_pol_Rpb1_3 PF04983.13 EKG20399.1 - 0.079 12.6 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 MtrG PF04210.8 EKG20399.1 - 0.084 12.5 0.5 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4618 PF15397.1 EKG20399.1 - 0.15 11.3 21.5 0.02 14.2 1.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF2205 PF10224.4 EKG20399.1 - 1.6 8.3 11.4 0.11 12.0 3.6 2.3 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) Reo_sigmaC PF04582.7 EKG20399.1 - 1.8 7.6 9.3 0.6 9.2 3.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4600 PF15372.1 EKG20399.1 - 2.1 8.5 16.5 0.73 10.0 7.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF972 PF06156.8 EKG20399.1 - 2.4 8.5 20.4 0.077 13.3 3.6 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF972) G-alpha PF00503.15 EKG20400.1 - 4e-117 391.1 0.4 4.8e-117 390.9 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EKG20400.1 - 4.2e-14 52.1 0.4 4e-09 35.9 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EKG20400.1 - 7.6e-05 21.9 1.9 0.0037 16.4 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF2985 PF11204.3 EKG20400.1 - 0.011 15.5 0.0 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) AAA_29 PF13555.1 EKG20400.1 - 0.048 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EKG20400.1 - 0.059 13.8 0.0 8.6 6.8 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein DUF1713 PF08213.6 EKG20401.1 - 4.4e-15 54.9 18.8 1e-14 53.8 13.0 1.7 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) MBD_C PF14048.1 EKG20401.1 - 0.62 10.6 4.0 1 9.9 0.4 2.8 2 1 1 3 3 3 0 C-terminal domain of methyl-CpG binding protein 2 and 3 IDO PF01231.13 EKG20402.1 - 5.5e-167 555.4 0.0 6.4e-167 555.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EKG20402.1 - 0.13 10.7 0.0 0.36 9.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) TFIIA PF03153.8 EKG20403.1 - 0.63 9.8 11.5 0.86 9.4 8.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EKG20403.1 - 2.3 6.3 11.3 2.7 6.1 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 EKG20404.1 - 8.5e-58 195.5 0.0 1.3e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20404.1 - 2.4e-21 75.9 0.1 4.5e-21 75.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EKG20404.1 - 0.013 15.2 0.0 0.048 13.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKG20404.1 - 0.16 11.5 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase YppF PF14178.1 EKG20404.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 YppF-like protein Pex24p PF06398.6 EKG20405.1 - 6.2e-86 288.4 0.0 7.4e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EKG20405.1 - 0.028 12.5 0.0 0.042 12.0 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3292 PF11696.3 EKG20405.1 - 0.095 10.5 0.1 0.15 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PRT_C PF08372.5 EKG20405.1 - 1.7 8.1 3.9 0.39 10.2 0.1 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Glyco_hydro_72 PF03198.9 EKG20407.1 - 1.2e-134 448.2 6.1 1.4e-134 448.0 4.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EKG20407.1 - 1.1e-06 27.8 0.1 1.6e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EKG20407.1 - 2.7e-06 26.7 0.8 3.3e-05 23.2 0.5 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MMR_HSR1_C PF08438.5 EKG20408.1 - 1.6e-33 115.2 0.0 3.4e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EKG20408.1 - 5.4e-18 65.0 0.0 1.6e-17 63.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG20408.1 - 8.5e-09 34.8 0.1 2e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EKG20408.1 - 0.00039 19.8 0.0 0.14 11.5 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EKG20408.1 - 0.016 15.5 0.1 0.57 10.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EKG20408.1 - 0.023 14.5 0.2 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain VirB8 PF04335.8 EKG20408.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 VirB8 protein Dynamin_N PF00350.18 EKG20408.1 - 0.03 14.1 1.9 0.16 11.7 0.2 2.5 3 0 0 3 3 3 0 Dynamin family AAA_18 PF13238.1 EKG20408.1 - 0.064 13.5 0.2 2.7 8.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain ArgK PF03308.11 EKG20408.1 - 0.067 11.9 0.1 0.22 10.2 0.0 1.9 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 EKG20408.1 - 0.097 12.1 0.1 8.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KTI12 PF08433.5 EKG20408.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Meth_synt_2 PF01717.13 EKG20409.1 - 0.009 15.0 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain PAN_3 PF08277.7 EKG20409.1 - 0.027 14.1 0.8 0.048 13.2 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain Pkinase PF00069.20 EKG20410.1 - 3.2e-63 213.3 0.0 3.9e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20410.1 - 5.5e-29 101.0 0.0 7.2e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG20410.1 - 0.015 14.2 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EKG20410.1 - 0.036 13.8 0.1 0.11 12.2 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Flavodoxin_4 PF12682.2 EKG20410.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin Sugar_tr PF00083.19 EKG20411.1 - 5.5e-90 302.0 13.6 8.7e-90 301.4 9.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20411.1 - 8.9e-33 113.4 28.5 1e-26 93.4 3.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG20411.1 - 1.1e-05 23.8 0.8 1.1e-05 23.8 0.6 2.1 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YqbF PF14553.1 EKG20412.1 - 0.1 12.3 0.3 11 5.7 0.0 2.5 2 0 0 2 2 2 0 YqbF, hypothetical protein domain GATA PF00320.22 EKG20413.1 - 1.2e-06 27.7 0.2 0.026 13.8 0.0 2.7 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 EKG20414.1 - 8.2e-19 66.9 0.0 1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.12 EKG20415.1 - 1.5e-34 119.0 0.1 1.8e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain Fzo_mitofusin PF04799.8 EKG20417.1 - 0.016 14.6 0.4 0.025 13.9 0.2 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF3811 PF11656.3 EKG20417.1 - 0.024 14.6 1.7 1.8 8.7 0.3 2.5 2 0 0 2 2 2 0 YjbD family (DUF3811) TPR_MLP1_2 PF07926.7 EKG20417.1 - 0.076 12.7 1.6 0.13 11.9 1.1 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Prismane PF03063.15 EKG20417.1 - 0.12 10.6 0.1 0.16 10.3 0.1 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF2968 PF11180.3 EKG20417.1 - 0.99 8.7 9.3 1.2 8.5 6.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) AA_permease PF00324.16 EKG20418.1 - 1.9e-128 428.8 35.2 2.1e-128 428.6 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG20418.1 - 3.1e-33 114.9 38.7 4.3e-33 114.4 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease Adeno_E3_14_5 PF04834.7 EKG20418.1 - 5.5 7.4 5.5 2.6 8.5 1.5 2.3 2 0 0 2 2 2 0 Early E3 14.5 kDa protein CBS PF00571.23 EKG20420.1 - 4.8e-26 90.2 10.7 7e-12 44.9 0.2 4.3 4 0 0 4 4 4 4 CBS domain PP2C PF00481.16 EKG20421.1 - 5.6e-64 215.9 0.1 3e-51 174.2 0.1 3.4 2 1 0 2 2 2 2 Protein phosphatase 2C Snf7 PF03357.16 EKG20422.1 - 1.2e-36 125.6 20.2 1.7e-36 125.1 12.6 1.8 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EKG20422.1 - 0.039 11.8 3.7 0.048 11.5 2.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EKG20422.1 - 0.1 11.9 4.9 0.17 11.3 3.4 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway YlqD PF11068.3 EKG20422.1 - 0.25 11.3 21.1 9.2 6.3 5.6 2.2 1 1 1 2 2 2 0 YlqD protein Peptidase_S46 PF10459.4 EKG20422.1 - 0.48 8.7 6.3 0.62 8.4 4.3 1.1 1 0 0 1 1 1 0 Peptidase S46 HrpB7 PF09486.5 EKG20422.1 - 0.56 10.1 8.5 4.8 7.0 5.9 2.3 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Dynamin_N PF00350.18 EKG20423.1 - 4.4e-16 59.1 0.6 9.7e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EKG20423.1 - 4.4e-09 36.3 0.0 3.5e-08 33.4 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG20423.1 - 4.9e-07 29.3 0.3 3.1e-06 26.7 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.4 EKG20423.1 - 0.0019 17.7 0.4 0.0076 15.7 0.3 2.0 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Toxin_47 PF15527.1 EKG20423.1 - 0.011 15.5 0.9 0.02 14.6 0.1 1.9 2 0 0 2 2 2 0 Putative toxin 47 IIGP PF05049.8 EKG20423.1 - 0.023 13.5 0.0 0.044 12.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EKG20423.1 - 0.048 14.1 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 EKG20423.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4604 PF15377.1 EKG20424.1 - 1.7e-14 54.3 18.6 1.9e-14 54.1 12.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Cut8_N PF14482.1 EKG20424.1 - 0.46 10.5 5.8 3 7.9 0.1 3.1 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Glyco_transf_15 PF01793.11 EKG20425.1 - 2.7e-133 443.9 4.7 3.5e-133 443.6 3.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF883 PF05957.8 EKG20426.1 - 5.1 7.5 7.2 40 4.6 1.7 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Ran_BP1 PF00638.13 EKG20427.1 - 1.3e-49 167.3 1.5 2e-49 166.7 1.0 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EKG20427.1 - 0.0004 20.0 0.2 0.0024 17.5 0.1 1.9 1 1 0 1 1 1 1 WH1 domain YEATS PF03366.11 EKG20428.1 - 5e-22 77.4 0.1 8.6e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 YEATS family Glyco_hydro_47 PF01532.15 EKG20429.1 - 4.2e-14 52.0 0.0 7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.15 EKG20430.1 - 2e-26 92.6 0.0 2.2e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Flu_C_NS2 PF03555.9 EKG20430.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Influenza C non-structural protein (NS2) TetM_leader PF08076.6 EKG20430.1 - 0.17 11.4 0.3 0.28 10.7 0.2 1.3 1 0 0 1 1 1 0 Tetracycline resistance determinant leader peptide DUF1129 PF06570.6 EKG20431.1 - 0.48 9.6 1.8 1.3 8.3 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) STE2 PF02116.10 EKG20432.1 - 1.3e-78 263.9 20.3 1.7e-78 263.5 14.1 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR HSP70 PF00012.15 EKG20433.1 - 6.6e-06 24.3 0.0 8.7e-06 23.9 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein HRXXH PF13933.1 EKG20434.1 - 0.018 14.4 3.0 0.089 12.1 2.1 1.9 1 1 0 1 1 1 0 Putative peptidase family SOG2 PF10428.4 EKG20435.1 - 0.0094 14.6 0.6 0.01 14.5 0.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Pex14_N PF04695.8 EKG20435.1 - 0.017 15.2 0.6 0.022 14.7 0.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2413 PF10310.4 EKG20435.1 - 0.025 13.4 9.1 0.032 13.0 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF605 PF04652.11 EKG20435.1 - 0.16 11.3 10.3 0.19 11.0 7.1 1.1 1 0 0 1 1 1 0 Vta1 like PALP PF00291.20 EKG20435.1 - 0.43 9.7 4.3 0.58 9.3 3.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Med3 PF11593.3 EKG20435.1 - 0.45 9.7 7.5 0.56 9.3 5.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lin-8 PF03353.10 EKG20435.1 - 0.69 9.1 5.8 0.82 8.9 4.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC27 PF09507.5 EKG20435.1 - 1.4 8.0 10.9 1.8 7.6 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 EKG20435.1 - 7 4.9 15.1 9.8 4.5 10.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 EKG20435.1 - 8.4 4.4 7.6 9.4 4.3 5.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 EKG20436.1 - 1.6e-26 93.2 7.4 1.9e-26 92.9 5.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG20436.1 - 1.1e-14 54.4 3.0 1.5e-14 54.0 2.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG20436.1 - 1.1e-09 38.4 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EKG20436.1 - 8.7e-05 22.0 0.4 0.0003 20.2 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EKG20436.1 - 0.00025 21.1 0.0 0.00043 20.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EKG20436.1 - 0.0018 18.0 0.3 0.012 15.3 0.2 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EKG20436.1 - 0.0033 16.3 0.0 0.0038 16.1 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Tautomerase PF01361.16 EKG20437.1 - 0.043 13.4 0.2 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Tautomerase enzyme Fungal_trans PF04082.13 EKG20438.1 - 0.00089 18.2 0.1 0.0011 17.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Smac_DIABLO PF09057.5 EKG20438.1 - 0.066 12.3 0.1 0.095 11.8 0.1 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases GFA PF04828.9 EKG20439.1 - 1.1e-21 76.5 0.2 2e-21 75.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EKG20439.1 - 0.032 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Polysacc_deac_1 PF01522.16 EKG20442.1 - 1.4e-15 57.0 0.0 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase MIP PF00230.15 EKG20443.1 - 1.5e-49 168.4 17.1 1.9e-49 168.1 11.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2749 PF10907.3 EKG20444.1 - 6.2 6.7 6.2 0.74 9.7 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2749) PIF1 PF05970.9 EKG20445.1 - 3.4e-62 210.4 0.3 1.5e-47 162.2 0.1 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EKG20445.1 - 6e-18 65.1 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EKG20445.1 - 4.4e-08 33.3 0.0 1.3e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EKG20445.1 - 2.5e-05 22.2 0.1 0.00014 19.8 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA_19 PF13245.1 EKG20445.1 - 3.6e-05 23.4 0.2 3.6e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 EKG20445.1 - 7.8e-05 22.7 0.0 0.00076 19.5 0.0 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EKG20445.1 - 0.00011 22.2 0.1 0.00053 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EKG20445.1 - 0.00093 19.4 0.1 0.0027 17.8 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EKG20445.1 - 0.0011 19.2 0.4 0.023 15.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter T2SE PF00437.15 EKG20445.1 - 0.0039 16.1 0.3 0.0065 15.4 0.2 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 EKG20445.1 - 0.0043 16.7 1.7 0.053 13.2 0.3 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EKG20445.1 - 0.0059 15.8 0.2 0.025 13.7 0.1 2.1 2 1 1 3 3 3 1 PhoH-like protein DUF2075 PF09848.4 EKG20445.1 - 0.0071 15.3 0.0 0.0071 15.3 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 EKG20445.1 - 0.011 15.3 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Helicase NACHT PF05729.7 EKG20445.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 EKG20445.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EKG20445.1 - 0.019 15.1 0.0 0.068 13.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EKG20445.1 - 0.021 14.3 0.0 6.4 6.2 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EKG20445.1 - 0.028 13.9 2.1 0.48 9.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 EKG20445.1 - 0.029 14.2 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EKG20445.1 - 0.059 12.8 0.2 0.88 9.0 0.2 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase Arch_ATPase PF01637.13 EKG20445.1 - 0.067 12.8 1.1 0.7 9.5 0.7 2.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EKG20445.1 - 0.07 12.5 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.2 EKG20445.1 - 0.097 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 RRM_1 PF00076.17 EKG20446.1 - 1.8e-60 200.4 0.0 2.6e-21 75.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG20446.1 - 3.2e-43 145.5 0.0 1.2e-13 50.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG20446.1 - 1.1e-28 98.8 0.0 4.6e-10 39.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EKG20446.1 - 2.2e-08 33.7 0.0 0.013 15.3 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EKG20446.1 - 0.00014 21.5 0.0 0.69 9.6 0.0 3.2 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EKG20446.1 - 0.022 14.6 0.0 0.66 9.9 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) eIF-3_zeta PF05091.7 EKG20447.1 - 0.0031 16.2 5.9 0.0035 16.0 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNA_pol_Rpb1_5 PF04998.12 EKG20447.1 - 0.0046 16.2 0.4 0.0046 16.2 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Caldesmon PF02029.10 EKG20447.1 - 0.011 14.2 21.9 0.017 13.5 15.2 1.3 1 0 0 1 1 1 0 Caldesmon RNase_H2-Ydr279 PF09468.5 EKG20447.1 - 0.028 13.6 16.0 0.042 13.0 11.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) LicD PF04991.8 EKG20447.1 - 0.032 14.3 5.8 0.044 13.8 4.0 1.2 1 0 0 1 1 1 0 LicD family U79_P34 PF03064.11 EKG20447.1 - 0.065 12.7 15.9 0.12 11.9 11.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zip PF02535.17 EKG20447.1 - 0.1 11.5 3.7 0.14 11.1 2.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dehalogenase PF13486.1 EKG20447.1 - 0.14 11.5 4.7 0.26 10.7 3.2 1.4 1 0 0 1 1 1 0 Reductive dehalogenase subunit PA26 PF04636.8 EKG20447.1 - 0.44 9.1 7.3 0.61 8.7 5.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) AAA_23 PF13476.1 EKG20447.1 - 0.51 10.6 17.6 0.74 10.0 12.2 1.2 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 EKG20447.1 - 1.2 6.7 15.1 1.5 6.4 10.4 1.1 1 0 0 1 1 1 0 Ycf1 Paramyxo_ncap PF00973.14 EKG20447.1 - 1.3 7.6 7.3 1.7 7.2 5.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Raftlin PF15250.1 EKG20447.1 - 1.5 7.2 12.0 2.3 6.6 8.3 1.2 1 0 0 1 1 1 0 Raftlin DUF4175 PF13779.1 EKG20447.1 - 1.7 6.2 17.0 2.7 5.5 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2413 PF10310.4 EKG20447.1 - 1.7 7.3 27.5 0.023 13.5 11.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) GAGA_bind PF06217.7 EKG20447.1 - 1.8 8.4 14.9 0.086 12.7 6.1 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family SR-25 PF10500.4 EKG20447.1 - 1.8 7.9 21.5 0.23 10.9 11.4 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_11 PF13086.1 EKG20447.1 - 1.9 7.9 8.2 2.7 7.4 5.7 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 EKG20447.1 - 1.9 8.2 23.2 0.059 13.2 10.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.6 EKG20447.1 - 2.1 6.3 13.8 2.8 5.9 9.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.10 EKG20447.1 - 2.8 6.4 13.2 4.6 5.7 9.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rtf2 PF04641.7 EKG20447.1 - 5.7 6.0 20.6 3.6 6.7 11.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger NARP1 PF12569.3 EKG20447.1 - 6 5.4 25.0 0.049 12.3 11.9 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Nop14 PF04147.7 EKG20447.1 - 6.2 4.6 24.8 8.4 4.1 17.2 1.2 1 0 0 1 1 1 0 Nop14-like family APG6 PF04111.7 EKG20447.1 - 9 5.2 15.4 12 4.7 10.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 p450 PF00067.17 EKG20448.1 - 2.9e-49 167.8 0.0 3.7e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG20449.1 - 7.2e-48 163.2 0.0 1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3042 PF11240.3 EKG20449.1 - 0.0033 17.1 2.7 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3042) DUF349 PF03993.7 EKG20449.1 - 0.68 10.1 4.4 4.6 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) MAPEG PF01124.13 EKG20450.1 - 3e-14 52.7 0.6 3e-14 52.7 0.4 1.8 1 1 1 2 2 2 1 MAPEG family Methyltransf_23 PF13489.1 EKG20453.1 - 0.00039 20.1 0.0 0.00068 19.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 EKG20454.1 - 7.5e-46 156.5 0.0 8.8e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 EKG20455.1 - 1.1e-39 135.8 0.0 1.8e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 EKG20456.1 - 2.3e-36 125.3 0.0 2.5e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_molyb PF00174.14 EKG20457.1 - 1.1e-41 142.0 0.0 1.6e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EKG20457.1 - 2.2e-15 56.4 0.1 3.4e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cu-oxidase_3 PF07732.10 EKG20459.1 - 8.1e-40 135.2 1.0 1.1e-39 134.8 0.7 1.2 1 0 0 1 1 1 1 Multicopper oxidase Glyco_hydro_12 PF01670.11 EKG20460.1 - 7.1e-33 113.6 1.1 7.1e-33 113.6 0.8 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 EKG20460.1 - 0.012 15.7 0.5 0.026 14.6 0.3 1.6 1 0 0 1 1 1 0 Phage holin Urb2 PF10441.4 EKG20461.1 - 0.074 12.6 0.3 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family DUF2244 PF10003.4 EKG20461.1 - 0.23 10.8 3.2 0.25 10.6 0.2 2.7 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) FA_desaturase PF00487.19 EKG20461.1 - 1.2 8.5 5.5 0.28 10.5 0.5 2.2 1 1 1 2 2 2 0 Fatty acid desaturase FAD_binding_4 PF01565.18 EKG20463.1 - 6.4e-07 28.9 0.1 8.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG20464.1 - 1.1e-13 50.8 0.7 2e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EKG20464.1 - 0.013 14.6 0.1 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding ETX_MTX2 PF03318.8 EKG20465.1 - 0.004 16.7 1.5 0.0074 15.8 1.0 1.4 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Dicty_CAR PF05462.6 EKG20468.1 - 2.1e-09 36.7 0.2 2.5e-09 36.4 0.1 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EKG20468.1 - 6e-08 32.0 0.6 7.1e-08 31.8 0.4 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.4 EKG20468.1 - 0.0014 17.8 1.2 0.0017 17.5 0.8 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3 PF11710.3 EKG20468.1 - 0.0048 16.4 0.5 0.0057 16.2 0.3 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EKG20468.1 - 0.013 14.6 2.4 0.019 14.1 1.7 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.12 EKG20468.1 - 0.048 12.4 2.2 0.83 8.3 1.6 2.0 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region UPF0233 PF06781.7 EKG20468.1 - 0.64 9.6 3.6 8.1 6.1 1.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) UcrQ PF02939.11 EKG20470.1 - 4.2e-14 52.1 0.0 5.2e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 UcrQ family adh_short PF00106.20 EKG20471.1 - 1.5e-14 54.2 0.9 1.5e-14 54.2 0.6 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG20471.1 - 2.8e-06 27.1 0.6 5e-06 26.2 0.4 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG20471.1 - 0.00025 20.9 0.1 0.00043 20.1 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.11 EKG20472.1 - 1e-09 37.6 0.4 1.3e-09 37.2 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20472.1 - 0.041 12.4 3.1 0.32 9.5 2.1 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter ERG2_Sigma1R PF04622.7 EKG20473.1 - 3.4e-27 95.1 0.1 4.3e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PLA2_B PF01735.13 EKG20474.1 - 2.5e-120 401.9 1.4 3.1e-120 401.6 1.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain CENP-Q PF13094.1 EKG20475.1 - 0.0014 18.6 0.1 0.0032 17.5 0.1 1.5 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EKG20475.1 - 0.002 17.7 0.2 0.002 17.7 0.1 1.4 2 0 0 2 2 2 1 IncA protein TMEM247 PF15444.1 EKG20475.1 - 0.011 15.5 0.5 0.022 14.5 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 Macoilin PF09726.4 EKG20475.1 - 0.017 13.4 1.5 0.027 12.7 1.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Vps5 PF09325.5 EKG20475.1 - 0.13 11.4 3.1 0.22 10.7 2.2 1.2 1 0 0 1 1 1 0 Vps5 C terminal like APG6 PF04111.7 EKG20475.1 - 1.3 8.0 4.8 1.8 7.5 3.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1793 PF08760.6 EKG20477.1 - 3.1e-31 108.5 0.0 5e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Peptidase_S24 PF00717.18 EKG20479.1 - 9.5e-06 25.1 0.2 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EKG20479.1 - 1.7e-05 24.3 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 Signal peptidase, peptidase S26 Cupin_8 PF13621.1 EKG20480.1 - 8.7e-52 176.1 0.1 9.8e-52 175.9 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EKG20480.1 - 0.017 14.4 0.0 3.6 6.7 0.1 2.4 2 0 0 2 2 2 0 Cupin superfamily protein Amidohydro_2 PF04909.9 EKG20481.1 - 2.6e-45 155.1 0.1 3e-45 154.9 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EKG20481.1 - 0.071 12.2 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase 2OG-FeII_Oxy PF03171.15 EKG20482.1 - 1.5e-16 60.4 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-DHHC PF01529.15 EKG20483.1 - 2.1e-43 147.7 2.7 4.4e-43 146.6 1.9 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EKG20483.1 - 0.049 13.4 6.2 0.13 12.1 4.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Yip1 PF04893.12 EKG20483.1 - 0.9 9.0 10.4 0.039 13.4 1.3 2.3 2 0 0 2 2 2 0 Yip1 domain APH PF01636.18 EKG20484.1 - 1.2e-13 51.4 0.0 3.2e-13 49.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKG20484.1 - 0.0044 16.6 0.0 0.0094 15.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3317 PF11779.3 EKG20486.1 - 4.9e-11 41.8 3.2 8.1e-11 41.1 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DNA_pol_B PF00136.16 EKG20487.1 - 3.1e-145 484.5 2.6 4.4e-145 484.0 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EKG20487.1 - 1e-83 280.9 0.0 1.7e-83 280.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EKG20487.1 - 1.1e-23 83.0 5.3 2.6e-23 81.7 3.7 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 EKG20487.1 - 0.00078 19.0 0.1 0.0017 17.9 0.1 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EKG20487.1 - 0.00082 19.2 0.3 0.0035 17.1 0.2 2.2 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.17 EKG20487.1 - 0.021 14.5 7.3 0.33 10.6 0.7 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_A_exo1 PF01612.15 EKG20487.1 - 0.059 12.8 0.5 0.41 10.0 0.1 2.5 2 0 0 2 2 2 0 3'-5' exonuclease JAB PF01398.16 EKG20488.1 - 9e-30 102.7 0.1 1.5e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EKG20488.1 - 1.6e-08 34.0 0.0 3.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EKG20488.1 - 0.061 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) IncA PF04156.9 EKG20489.1 - 0.051 13.1 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 EKG20489.1 - 0.091 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VPEP PF07589.6 EKG20489.1 - 0.65 9.9 3.1 0.81 9.6 1.4 1.8 1 1 0 1 1 1 0 PEP-CTERM motif HsbA PF12296.3 EKG20490.1 - 3.7e-12 46.1 0.3 3.7e-12 46.1 0.2 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A TPP_enzyme_N PF02776.13 EKG20490.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain tRNA-synt_1c PF00749.16 EKG20491.1 - 2e-98 328.9 0.0 2.6e-98 328.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ATG16 PF08614.6 EKG20492.1 - 1.5e-45 155.4 9.8 2.2e-45 154.9 6.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CENP-Q PF13094.1 EKG20492.1 - 2.6e-05 24.2 9.0 2.6e-05 24.2 6.3 2.1 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.1 EKG20492.1 - 8.4e-05 22.0 9.2 8.4e-05 22.0 6.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EKG20492.1 - 0.011 14.9 4.0 0.016 14.3 2.8 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EKG20492.1 - 0.018 14.8 0.4 0.018 14.8 0.3 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Noelin-1 PF12308.3 EKG20492.1 - 0.1 12.4 3.3 0.09 12.5 0.6 2.0 1 1 1 2 2 2 0 Neurogenesis glycoprotein Laminin_II PF06009.7 EKG20492.1 - 0.2 11.4 10.8 0.41 10.4 4.7 2.2 1 1 1 2 2 2 0 Laminin Domain II KxDL PF10241.4 EKG20492.1 - 0.2 11.5 7.5 2.8 7.9 0.3 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein Baculo_PEP_C PF04513.7 EKG20492.1 - 0.31 10.8 4.2 0.59 9.9 2.9 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus GvpG PF05120.7 EKG20492.1 - 0.38 10.6 12.0 0.044 13.6 2.7 2.9 1 1 2 3 3 3 0 Gas vesicle protein G CCDC144C PF14915.1 EKG20492.1 - 0.63 8.9 20.8 0.31 9.9 11.1 2.4 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region KIAA1430 PF13879.1 EKG20492.1 - 0.64 10.4 5.0 0.25 11.7 1.3 2.0 2 1 0 2 2 1 0 KIAA1430 homologue Atg14 PF10186.4 EKG20492.1 - 0.82 8.5 13.4 0.4 9.5 7.7 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EKG20492.1 - 1 8.3 15.8 0.16 11.0 8.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EKG20492.1 - 1.1 8.7 17.6 1.1 8.8 9.9 2.4 2 1 0 2 2 2 0 IncA protein Spc7 PF08317.6 EKG20492.1 - 1.4 7.5 11.7 4.5 5.8 8.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EKG20492.1 - 2.5 5.8 7.0 3.2 5.4 4.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EKG20492.1 - 2.8 6.3 9.4 0.18 10.2 3.2 1.4 2 0 0 2 2 2 0 AAA domain FlxA PF14282.1 EKG20492.1 - 2.8 7.9 11.1 0.53 10.2 1.4 2.8 2 1 1 3 3 3 0 FlxA-like protein Nup54 PF13874.1 EKG20492.1 - 2.9 7.5 16.9 1.3 8.6 1.6 2.9 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF2968 PF11180.3 EKG20492.1 - 3 7.1 22.4 9.8 5.5 10.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) GAS PF13851.1 EKG20492.1 - 4 6.5 18.6 0.33 10.1 9.0 2.0 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EKG20492.1 - 5.4 6.9 22.2 0.12 12.3 1.8 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.15 EKG20492.1 - 5.9 5.8 27.9 0.27 10.2 5.7 2.9 2 1 1 3 3 3 0 Tropomyosin Sensor PF13796.1 EKG20492.1 - 7.4 6.1 6.5 0.85 9.2 0.2 2.1 1 1 1 2 2 2 0 Putative sensor NTR2 PF15458.1 EKG20492.1 - 8.8 5.4 16.9 0.11 11.7 3.6 2.4 1 1 1 2 2 2 0 Nineteen complex-related protein 2 Heme_oxygenase PF01126.15 EKG20493.1 - 3.3e-13 49.6 0.0 1.5e-11 44.2 0.0 2.3 2 1 0 2 2 2 2 Heme oxygenase FtsH_ext PF06480.10 EKG20493.1 - 0.14 12.2 0.4 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 FtsH Extracellular PBP PF01161.15 EKG20494.1 - 2.6e-13 50.0 0.0 4.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein EcKinase PF02958.15 EKG20494.1 - 0.06 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase IF3_C PF00707.17 EKG20495.1 - 9.3e-13 47.7 0.1 2.2e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EKG20495.1 - 0.002 17.4 0.4 0.002 17.4 0.3 2.6 2 1 1 3 3 3 2 Mitochondrial translation initiation factor DUF2605 PF10792.4 EKG20495.1 - 0.021 14.5 0.6 0.1 12.2 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2605) HTH_WhiA PF02650.9 EKG20495.1 - 0.05 13.9 0.1 0.093 13.1 0.1 1.4 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Ribosomal_L4 PF00573.17 EKG20496.1 - 5.3e-46 156.4 0.0 6.4e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family CTDII PF01556.13 EKG20497.1 - 2.5e-20 72.1 0.1 4.8e-18 64.8 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKG20497.1 - 2.4e-13 49.9 19.6 4.1e-13 49.1 13.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EKG20497.1 - 1.3 8.7 12.1 1.4 8.6 1.9 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Sugar_tr PF00083.19 EKG20499.1 - 8.9e-87 291.5 19.8 1e-86 291.3 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20499.1 - 1.3e-33 116.2 20.3 1.5e-32 112.6 12.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_12 PF13087.1 EKG20501.1 - 6.2e-25 87.7 0.0 9.9e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG20501.1 - 1.2e-20 74.0 0.0 2.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EKG20501.1 - 3e-08 33.5 0.0 0.00044 19.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EKG20501.1 - 5.6e-05 22.8 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EKG20501.1 - 0.00012 22.1 0.0 0.014 15.5 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EKG20501.1 - 0.0002 20.7 0.1 0.00098 18.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EKG20501.1 - 0.0043 16.0 0.5 0.37 9.7 0.0 3.0 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EKG20501.1 - 0.0083 16.1 0.2 0.2 11.6 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain UvrD-helicase PF00580.16 EKG20501.1 - 0.013 14.8 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 EKG20501.1 - 0.017 15.3 0.0 0.079 13.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG20501.1 - 0.024 15.4 0.0 0.13 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EKG20501.1 - 0.051 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKG20501.1 - 0.069 12.5 0.8 4.9 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Mg_chelatase PF01078.16 EKG20501.1 - 0.13 11.3 0.2 0.84 8.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EKG20501.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKG20501.1 - 0.14 11.8 0.3 1 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PLDc_2 PF13091.1 EKG20502.1 - 3e-16 59.2 0.0 2e-06 27.5 0.0 4.9 4 1 0 4 4 4 3 PLD-like domain PLDc PF00614.17 EKG20502.1 - 7.3e-15 54.2 0.8 4.1e-06 26.4 0.0 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif Cyanate_lyase PF02560.9 EKG20503.1 - 1.7e-33 113.9 0.0 2.4e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 EKG20503.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 EKG20503.1 - 0.018 14.9 0.2 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix zf-C2H2 PF00096.21 EKG20504.1 - 4.3e-09 36.1 32.2 0.044 14.1 0.1 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG20504.1 - 2.5e-05 24.2 32.1 0.79 10.1 0.4 6.5 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EKG20504.1 - 0.045 13.6 0.1 0.045 13.6 0.1 4.9 6 0 0 6 6 6 0 C2H2-type zinc finger zf-FCS PF06467.9 EKG20504.1 - 0.11 12.1 9.5 0.62 9.7 0.7 3.6 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif UPF0547 PF10571.4 EKG20504.1 - 0.19 11.4 12.1 3.8 7.2 0.1 4.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 VP_N-CPKC PF11475.3 EKG20504.1 - 0.42 10.1 0.0 0.42 10.1 0.0 2.6 3 0 0 3 3 3 0 Virion protein N terminal domain DNA_ligase_A_M PF01068.16 EKG20505.1 - 3.2e-48 163.7 0.0 5.4e-47 159.7 0.0 2.4 2 1 1 3 3 3 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EKG20505.1 - 1e-37 129.6 0.0 1.7e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EKG20505.1 - 3.4e-14 53.0 0.1 1.7e-13 50.7 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EKG20505.1 - 0.0066 16.5 0.0 1.1 9.4 0.0 3.0 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EKG20505.1 - 0.012 15.3 0.1 0.21 11.2 0.1 2.8 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain EF-hand_4 PF12763.2 EKG20506.1 - 8.4e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SLBP_RNA_bind PF15247.1 EKG20506.1 - 0.13 12.0 3.8 0.26 11.0 2.6 1.4 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain ADH_zinc_N PF00107.21 EKG20507.1 - 2.9e-26 91.5 0.1 4.9e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG20507.1 - 1.9e-18 67.5 0.0 3.9e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG20507.1 - 2.5e-11 43.2 0.0 1.6e-09 37.5 0.0 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EKG20507.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Peptidase_M35 PF02102.10 EKG20509.1 - 4.9e-110 367.5 22.2 5.7e-110 367.3 15.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EKG20509.1 - 1.2e-08 35.6 1.3 1.2e-08 35.6 0.9 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase CARDB PF07705.6 EKG20509.1 - 0.00095 19.1 0.1 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 CARDB COesterase PF00135.23 EKG20511.1 - 1.9e-93 314.0 0.0 2.4e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG20511.1 - 6.9e-07 29.0 0.2 4.7e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG20511.1 - 0.064 12.4 0.1 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SDA1 PF05285.7 EKG20512.1 - 0.0057 15.9 13.4 0.0067 15.7 9.3 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.7 EKG20512.1 - 2 6.2 25.2 2.5 5.8 17.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EKG20512.1 - 5.2 4.9 19.7 6.5 4.6 13.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 EKG20512.1 - 9.5 5.5 7.9 11 5.2 5.5 1.2 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 EKG20513.1 - 1.4e-34 119.4 0.0 2.2e-21 75.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HET PF06985.6 EKG20514.1 - 2.2e-21 76.4 0.0 5.5e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EKG20516.1 - 0.036 14.2 0.2 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Ferritin_2 PF13668.1 EKG20517.1 - 4.3e-21 75.2 0.2 7.3e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Polyketide_cyc2 PF10604.4 EKG20517.1 - 2e-13 50.7 0.0 5.9e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HET PF06985.6 EKG20518.1 - 1.5e-20 73.7 0.0 2.7e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Retrotrans_gag PF03732.12 EKG20520.1 - 2.4e-14 53.1 0.8 5.3e-14 52.0 0.6 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein DUF972 PF06156.8 EKG20520.1 - 0.015 15.6 0.6 0.13 12.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EKG20520.1 - 0.078 12.4 1.3 0.26 10.7 0.9 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF1754 PF08555.5 EKG20522.1 - 7.7e-13 48.8 16.2 7.7e-13 48.8 11.2 1.7 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Sulfotransfer_2 PF03567.9 EKG20522.1 - 0.089 12.4 0.2 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Sulfotransferase family Cu-oxidase_2 PF07731.9 EKG20523.1 - 1.4e-25 89.4 4.0 3.4e-23 81.6 0.8 2.8 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG20523.1 - 3.6e-21 75.1 0.1 1.4e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EKG20523.1 - 1.2e-05 25.2 0.0 0.00045 20.1 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Atg14 PF10186.4 EKG20525.1 - 9.3e-23 80.6 0.1 1.4e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EKG20525.1 - 0.00011 21.3 0.1 0.00029 20.0 0.1 1.6 1 1 0 1 1 1 1 Autophagy protein Apg6 Spc7 PF08317.6 EKG20525.1 - 0.2 10.2 7.5 0.62 8.6 5.2 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 EKG20525.1 - 0.32 10.8 8.3 0.59 9.9 5.8 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GBP_C PF02841.9 EKG20525.1 - 1.5 7.9 8.8 2.4 7.2 6.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4463 PF14703.1 EKG20526.1 - 0.06 13.8 0.2 0.06 13.8 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) Peptidase_C37 PF05416.7 EKG20526.1 - 0.084 11.1 2.8 0.13 10.4 1.9 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RRF PF01765.14 EKG20526.1 - 0.14 11.6 10.6 0.51 9.7 1.8 2.4 1 1 1 2 2 2 0 Ribosome recycling factor TRAM_LAG1_CLN8 PF03798.11 EKG20527.1 - 1.6e-36 125.7 20.7 2.6e-36 125.0 14.4 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EKG20527.1 - 8.4e-23 79.6 0.0 1.8e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein DUF676 PF05057.9 EKG20531.1 - 6.6e-51 172.6 0.0 9.4e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EKG20531.1 - 2.8e-06 27.1 0.0 4.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG20531.1 - 2.9e-05 24.0 0.0 4.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EKG20531.1 - 0.00031 20.3 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EKG20531.1 - 0.00049 19.7 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.13 EKG20531.1 - 0.21 10.8 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) RNase_T PF00929.19 EKG20532.1 - 4.5e-11 43.2 0.0 1.2e-06 28.9 0.0 2.3 2 0 0 2 2 2 2 Exonuclease DUF1793 PF08760.6 EKG20534.1 - 1e-62 210.9 2.5 4.5e-62 208.9 0.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EKG20534.1 - 2.7e-05 23.4 0.5 6.1e-05 22.3 0.3 1.6 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal DUF608 PF04685.8 EKG20534.1 - 8.2e-05 21.4 0.2 0.00014 20.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 EKG20534.1 - 0.00065 18.0 1.9 0.00065 18.0 0.2 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DNA_pol_A PF00476.15 EKG20535.1 - 3.4e-101 338.6 0.0 8.6e-101 337.3 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 EKG20535.1 - 0.0094 15.4 0.2 0.074 12.5 0.1 2.2 1 1 0 1 1 1 1 3'-5' exonuclease Mad3_BUB1_I PF08311.7 EKG20535.1 - 0.062 13.0 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 zf-C3HC4_3 PF13920.1 EKG20536.1 - 4.7e-10 38.9 5.0 7.6e-10 38.3 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG20536.1 - 5.3e-10 38.9 5.6 8.1e-10 38.3 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKG20536.1 - 8.7e-10 38.4 5.5 1.4e-09 37.8 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG20536.1 - 1.9e-08 33.9 5.3 2.9e-08 33.2 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EKG20536.1 - 1.8e-07 30.6 4.9 3.3e-07 29.8 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EKG20536.1 - 0.00081 19.2 4.4 0.01 15.6 3.8 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EKG20536.1 - 0.02 14.4 3.0 0.039 13.5 2.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EKG20536.1 - 0.055 12.9 2.1 0.096 12.2 1.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EKG20536.1 - 0.097 12.7 1.1 0.22 11.6 0.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EKG20536.1 - 0.24 10.9 8.5 1.1 8.8 3.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EKG20536.1 - 0.6 9.8 11.4 0.076 12.7 1.4 3.2 3 1 0 3 3 3 0 RING-type zinc-finger FYVE PF01363.16 EKG20536.1 - 0.83 9.5 3.9 1.9 8.4 2.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger Fungal_trans PF04082.13 EKG20537.1 - 1.5e-18 66.6 0.0 2.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nop16 PF09420.5 EKG20538.1 - 6.8e-50 169.3 12.4 1e-49 168.7 8.6 1.3 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 MCR_C PF04609.7 EKG20538.1 - 0.39 9.4 2.1 0.57 8.9 0.2 2.0 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Zip PF02535.17 EKG20539.1 - 8.6e-58 195.8 5.6 2.8e-57 194.1 3.9 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_31 PF01055.21 EKG20540.1 - 1.7e-92 310.5 6.7 2.4e-92 310.0 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG20540.1 - 2.7e-06 27.1 0.1 8.3e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like AMP-binding PF00501.23 EKG20541.1 - 4.7e-42 143.8 0.0 5.3e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF3129 PF11327.3 EKG20542.1 - 4.9e-69 231.8 15.4 6.4e-69 231.4 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) GATA PF00320.22 EKG20543.1 - 1.7e-14 52.8 5.2 1.7e-14 52.8 3.6 1.7 2 0 0 2 2 2 1 GATA zinc finger SipA PF09052.5 EKG20543.1 - 0.058 11.7 0.0 0.082 11.3 0.0 1.2 1 0 0 1 1 1 0 Salmonella invasion protein A zf-RING_3 PF14369.1 EKG20543.1 - 0.25 11.3 1.9 0.51 10.3 1.3 1.5 1 0 0 1 1 1 0 zinc-finger DUF2014 PF09427.5 EKG20544.1 - 5.4e-101 337.1 3.1 8.3e-101 336.4 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EKG20544.1 - 9.5e-18 63.6 0.2 2.7e-17 62.1 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CAF-1_p150 PF11600.3 EKG20544.1 - 0.49 9.7 7.2 1.4 8.2 5.0 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF904 PF06005.7 EKG20544.1 - 2.9 8.2 8.1 19 5.6 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) ADIP PF11559.3 EKG20546.1 - 0.003 17.4 9.7 0.003 17.4 6.7 5.9 2 1 4 6 6 6 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EKG20546.1 - 0.0063 16.3 12.7 0.0063 16.3 8.8 6.2 3 1 3 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EKG20546.1 - 0.19 10.8 28.3 0.78 8.8 12.1 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CCDC155 PF14662.1 EKG20546.1 - 0.31 10.5 70.9 0.11 12.0 16.1 5.0 3 2 2 5 5 5 0 Coiled-coil region of CCDC155 Filament PF00038.16 EKG20546.1 - 0.7 9.2 57.6 0.014 14.8 11.1 3.9 2 1 2 4 4 4 0 Intermediate filament protein Fimbrial PF00419.15 EKG20546.1 - 1.1 9.4 5.2 2.2 8.4 3.6 1.5 1 0 0 1 1 1 0 Fimbrial protein TSC22 PF01166.13 EKG20546.1 - 2.1 8.3 27.3 1.5 8.8 0.3 5.9 2 2 2 5 5 5 0 TSC-22/dip/bun family SnoaL PF07366.7 EKG20547.1 - 1.2e-07 31.3 0.1 3.2e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EKG20547.1 - 7.6e-06 26.2 0.2 8.9e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EKG20547.1 - 0.058 13.4 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain YtzH PF14165.1 EKG20547.1 - 0.062 13.5 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 YtzH-like protein DND1_DSRM PF14709.1 EKG20547.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Ank_2 PF12796.2 EKG20549.1 - 4e-09 36.6 0.0 1.2e-07 31.9 0.0 2.7 2 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKG20549.1 - 2.7e-07 30.0 0.0 4.2 7.3 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EKG20549.1 - 3.8e-05 24.0 0.0 0.24 11.9 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG20549.1 - 0.00017 21.4 0.0 42 4.8 0.0 5.1 4 0 0 4 4 4 0 Ankyrin repeat GCS PF03074.11 EKG20550.1 - 3.5e-152 506.7 0.0 4.8e-152 506.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 EKG20550.1 - 0.056 12.5 0.0 0.56 9.2 0.0 2.2 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) DUF3669 PF12417.3 EKG20550.1 - 0.17 11.6 0.6 0.44 10.3 0.1 1.9 2 0 0 2 2 2 0 Zinc finger protein APH PF01636.18 EKG20552.1 - 3.5e-10 40.0 1.4 5.5e-10 39.3 1.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EKG20552.1 - 5.2e-10 38.7 0.0 4.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EKG20552.1 - 2.4e-07 30.1 0.0 6.3e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20552.1 - 2.1e-06 27.0 0.0 3.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EKG20552.1 - 3e-06 26.7 0.0 0.0041 16.4 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.20 EKG20553.1 - 1.6e-53 181.5 0.3 3.5e-53 180.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG20553.1 - 2.8e-26 92.1 0.0 4e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG20553.1 - 0.0078 15.2 0.0 0.017 14.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EKG20553.1 - 0.09 12.4 0.1 0.09 12.4 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family SAPS PF04499.10 EKG20553.1 - 0.092 11.3 0.7 0.13 10.8 0.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EKG20553.1 - 0.29 8.7 2.1 0.31 8.7 1.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 EKG20553.1 - 2.4 7.0 5.8 3.8 6.3 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_subunit PF08597.5 EKG20553.1 - 8.1 5.9 18.4 11 5.4 12.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Methyltransf_28 PF02636.12 EKG20554.1 - 3.1e-75 252.8 0.0 4.1e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Nop14 PF04147.7 EKG20556.1 - 1.7 6.4 22.3 2.4 5.9 15.4 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_N PF01194.12 EKG20558.1 - 1.2e-29 102.0 0.9 1.5e-29 101.8 0.6 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EKG20558.1 - 0.061 13.4 0.3 0.095 12.8 0.2 1.4 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.27 EKG20559.1 - 1.4e-08 34.2 0.8 0.0015 18.3 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF1864 PF08933.6 EKG20559.1 - 0.12 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Aerolysin PF01117.15 EKG20560.1 - 0.039 12.8 0.3 0.052 12.4 0.2 1.1 1 0 0 1 1 1 0 Aerolysin toxin Zn_clus PF00172.13 EKG20563.1 - 2.4e-09 36.9 11.4 4.1e-09 36.2 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EKG20563.1 - 8.7e-06 24.5 0.0 1.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3016 PF11454.3 EKG20563.1 - 0.059 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) DUF2797 PF10977.3 EKG20563.1 - 1.6 8.2 3.1 2.6 7.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) RTA1 PF04479.8 EKG20564.1 - 4.2e-56 189.9 9.0 5.5e-56 189.5 6.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2243 PF10002.4 EKG20564.1 - 0.027 14.2 0.7 0.065 13.0 0.5 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2243) Kei1 PF08552.6 EKG20564.1 - 0.029 14.0 0.4 0.059 13.0 0.3 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Phage_Gp23 PF10669.4 EKG20564.1 - 5.1 7.2 5.5 0.48 10.5 0.1 2.1 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Zn_clus PF00172.13 EKG20565.1 - 1.7e-09 37.3 6.0 2.9e-09 36.6 4.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 EKG20566.1 - 5.7e-34 117.9 0.8 7.8e-34 117.5 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG20566.1 - 1.1e-12 48.0 0.0 2.3e-12 46.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG20566.1 - 8.1e-08 32.1 0.0 3.6e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG20566.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase GFO_IDH_MocA_C PF02894.12 EKG20567.1 - 1.6e-08 34.3 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EKG20568.1 - 4.1e-24 85.4 0.0 5.4e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 EKG20568.1 - 0.0065 16.7 0.0 0.0095 16.1 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Gp_dh_N PF00044.19 EKG20568.1 - 0.0076 16.2 0.1 0.029 14.3 0.0 1.7 1 1 1 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EKG20568.1 - 0.021 14.6 0.1 0.036 13.9 0.1 1.3 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EKG20568.1 - 0.13 11.3 0.3 0.46 9.6 0.2 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF829 PF05705.9 EKG20569.1 - 5.5e-49 167.0 0.0 6.7e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EKG20569.1 - 0.0013 18.6 2.6 0.0025 17.7 1.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family LON PF02190.11 EKG20570.1 - 7.1e-29 100.9 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 EKG20570.1 - 2.5e-13 49.6 19.0 1.1e-07 31.6 4.6 3.0 2 1 1 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EKG20570.1 - 6.2e-12 45.0 19.9 2.6e-06 27.0 7.0 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG20570.1 - 1.4e-11 44.1 25.3 1.7e-06 27.9 7.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EKG20570.1 - 2.7e-11 42.9 20.1 2.8e-06 26.8 7.4 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG20570.1 - 2.4e-10 40.0 26.7 1.7e-06 27.7 8.6 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EKG20570.1 - 3.4e-10 39.4 17.9 3.1e-06 26.7 6.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG20570.1 - 5.3e-07 29.2 16.1 0.00033 20.2 2.0 3.1 2 1 1 3 3 3 2 RING-type zinc-finger U-box PF04564.10 EKG20570.1 - 0.013 15.4 0.5 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 U-box domain zf-RING_4 PF14570.1 EKG20570.1 - 0.044 13.3 18.5 0.018 14.5 4.1 3.6 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EKG20570.1 - 0.24 11.5 12.4 0.13 12.4 4.4 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger RICTOR_N PF14664.1 EKG20571.1 - 8.5e-139 462.2 1.6 2.9e-138 460.4 1.4 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EKG20571.1 - 3e-81 271.7 0.0 1.5e-80 269.4 0.0 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EKG20571.1 - 6.7e-42 142.0 0.0 8.2e-41 138.5 0.0 2.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EKG20571.1 - 4.8e-26 90.4 0.6 6.8e-25 86.7 0.0 3.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EKG20571.1 - 7.3e-10 38.4 11.6 2e-09 37.0 8.0 1.7 1 0 0 1 1 1 1 Hr1 repeat Uricase PF01014.13 EKG20572.1 - 6.5e-76 253.0 1.4 2.7e-38 131.1 0.6 2.1 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.13 EKG20573.1 - 4.3e-34 117.3 0.1 5.3e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Sod_Cu PF00080.15 EKG20574.1 - 2.5e-14 53.6 0.0 8.9e-14 51.8 0.0 1.7 1 1 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EKG20574.1 - 1.6e-12 47.4 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain TPR_1 PF00515.23 EKG20575.1 - 8.1e-17 60.0 8.2 5.4e-08 32.1 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EKG20575.1 - 1.5e-16 59.8 3.1 3.6e-11 42.5 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EKG20575.1 - 1.6e-15 55.6 5.4 3.5e-06 26.4 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EKG20575.1 - 2.9e-13 49.5 0.2 7e-08 32.3 0.0 2.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKG20575.1 - 7.1e-11 41.0 2.8 3.8e-05 23.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 EKG20575.1 - 4.1e-10 39.2 0.6 7.4e-10 38.3 0.4 1.5 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.1 EKG20575.1 - 1.1e-08 34.2 0.3 6.1e-07 28.7 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EKG20575.1 - 1.3e-08 34.7 0.4 0.21 12.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG20575.1 - 2.8e-06 27.8 1.0 0.0009 19.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EKG20575.1 - 3.4e-06 26.8 0.2 0.039 14.1 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG20575.1 - 0.00016 21.4 0.1 0.29 11.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG20575.1 - 0.00018 21.8 0.5 0.029 14.9 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EKG20575.1 - 0.00092 19.3 0.2 0.086 12.9 0.0 2.7 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EKG20575.1 - 0.0045 17.3 0.1 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EKG20575.1 - 0.027 14.3 0.5 2 8.4 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EKG20575.1 - 0.033 14.5 0.0 37 5.1 0.0 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Aldedh PF00171.17 EKG20577.1 - 6.8e-159 529.0 0.3 7.9e-159 528.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 EKG20578.1 - 7e-53 179.7 0.0 9.1e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG20578.1 - 3.6e-38 131.1 0.0 5.6e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG20578.1 - 1.7e-06 27.2 0.0 0.0023 16.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG20578.1 - 3.1e-05 23.0 0.0 0.065 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EKG20578.1 - 8.5e-05 21.6 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG20578.1 - 0.00026 20.9 0.0 0.00066 19.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EKG20578.1 - 0.013 14.5 0.8 0.16 10.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EKG20578.1 - 0.018 13.7 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.22 EKG20578.1 - 0.023 15.1 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG20578.1 - 0.024 14.6 0.0 1.6 8.7 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG20578.1 - 0.033 14.0 0.0 0.098 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA_C PF08546.6 EKG20579.1 - 1.3e-25 89.7 0.0 2.7e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EKG20579.1 - 1.7e-23 82.7 0.0 5.3e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA SATase_N PF06426.9 EKG20579.1 - 0.063 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Aldo_ket_red PF00248.16 EKG20580.1 - 3.7e-65 219.5 0.0 4.9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNase_H2-Ydr279 PF09468.5 EKG20581.1 - 0.016 14.4 5.0 0.026 13.7 3.4 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) 4HBT_3 PF13622.1 EKG20581.1 - 0.042 13.5 0.2 0.042 13.5 0.1 3.4 3 0 0 3 3 3 0 Thioesterase-like superfamily Peptidase_S49_N PF08496.5 EKG20581.1 - 0.046 13.5 4.9 0.09 12.5 3.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.3 EKG20581.1 - 0.81 8.3 7.6 1.2 7.7 5.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.11 EKG20581.1 - 5 6.4 6.2 44 3.3 3.4 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Lipase_3 PF01764.20 EKG20582.1 - 1e-05 25.1 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) SLBP_RNA_bind PF15247.1 EKG20582.1 - 0.073 12.8 1.0 0.17 11.6 0.7 1.6 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain VPS9 PF02204.13 EKG20583.1 - 1.3e-25 89.3 0.0 2.6e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PMC2NT PF08066.7 EKG20583.1 - 0.086 13.1 3.6 20 5.5 0.1 3.4 3 0 0 3 3 3 0 PMC2NT (NUC016) domain zf-LITAF-like PF10601.4 EKG20585.1 - 1.6e-21 75.9 7.2 2.3e-21 75.4 5.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.5 EKG20585.1 - 0.022 14.7 0.2 0.32 10.9 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain APC_CDC26 PF10471.4 EKG20585.1 - 0.13 12.9 4.9 0.41 11.4 3.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Lar_restr_allev PF14354.1 EKG20585.1 - 3.3 8.0 6.8 11 6.4 4.7 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar Cys_rich_VLP PF14194.1 EKG20587.1 - 0.1 12.3 0.2 0.22 11.2 0.2 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP YajC PF02699.10 EKG20588.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit AAA_12 PF13087.1 EKG20589.1 - 2.1e-34 118.6 0.0 3.4e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EKG20589.1 - 1.3e-23 83.8 0.0 2e-13 50.4 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EKG20589.1 - 9.2e-14 50.9 0.1 1.2e-10 40.9 0.0 3.6 2 1 1 3 3 3 1 Part of AAA domain AAA_30 PF13604.1 EKG20589.1 - 4.7e-07 29.5 0.0 6e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EKG20589.1 - 1.2e-06 28.1 0.0 6.6e-06 25.6 0.0 1.9 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 EKG20589.1 - 6.3e-05 22.5 0.0 0.16 11.3 0.0 2.2 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.9 EKG20589.1 - 0.00017 21.2 0.0 0.0012 18.4 0.0 2.2 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EKG20589.1 - 0.001 18.6 0.0 0.41 10.1 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EKG20589.1 - 0.0044 17.1 0.0 0.046 13.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EKG20589.1 - 0.0049 16.7 0.0 0.0098 15.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EKG20589.1 - 0.017 14.0 0.0 0.14 11.0 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EKG20589.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.24 EKG20589.1 - 0.042 13.3 0.0 0.1 12.0 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.11 EKG20589.1 - 0.067 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 EKG20589.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EKG20589.1 - 0.16 12.1 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GCIP PF13324.1 EKG20590.1 - 1.9e-10 40.4 0.8 1.9e-10 40.4 0.6 1.6 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting NIT PF08376.5 EKG20590.1 - 0.037 13.5 0.3 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 Nitrate and nitrite sensing GldM_N PF12081.3 EKG20590.1 - 0.049 13.1 0.6 0.097 12.1 0.4 1.5 1 0 0 1 1 1 0 GldM N-terminal domain CFEM PF05730.6 EKG20591.1 - 1.7e-12 46.9 13.7 5.1e-12 45.4 9.5 1.8 1 0 0 1 1 1 1 CFEM domain TFIIA PF03153.8 EKG20591.1 - 1.1 9.0 8.9 1.3 8.7 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.1 EKG20592.1 - 2.7e-17 62.9 0.0 4e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG20592.1 - 1.4e-07 32.0 0.0 1.7e-06 28.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG20592.1 - 6.4e-07 29.7 0.0 4.5e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG20592.1 - 4.5e-06 26.3 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EKG20592.1 - 4.6e-06 27.0 0.0 1.3e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG20592.1 - 0.017 15.4 0.0 0.055 13.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EKG20592.1 - 0.034 13.2 0.0 0.096 11.7 0.0 1.7 3 0 0 3 3 3 0 Putative methyltransferase AATase PF07247.7 EKG20593.1 - 5.5e-11 41.6 0.0 3.1e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Activator-TraM PF11657.3 EKG20594.1 - 0.024 14.1 1.2 0.05 13.0 0.8 1.4 1 0 0 1 1 1 0 Transcriptional activator TraM PRKCSH-like PF12999.2 EKG20595.1 - 4.7e-44 150.0 10.0 9e-26 90.5 1.4 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EKG20595.1 - 1.3e-32 112.4 4.3 5e-32 110.5 1.4 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EKG20595.1 - 1e-10 42.2 1.2 1e-10 42.2 0.8 2.7 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein TBPIP PF07106.8 EKG20595.1 - 0.63 9.5 11.5 0.99 8.9 3.4 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EKG20595.1 - 0.63 9.6 17.2 5.7 6.4 0.4 3.2 3 0 0 3 3 3 0 IncA protein Fib_alpha PF08702.5 EKG20595.1 - 1.7 8.7 9.1 3.5 7.7 2.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Jnk-SapK_ap_N PF09744.4 EKG20595.1 - 7.3 6.5 16.8 7 6.6 6.3 2.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Orexin PF02072.10 EKG20597.1 - 0.041 13.6 2.2 0.09 12.5 1.6 1.6 1 0 0 1 1 1 0 Prepro-orexin DUF1993 PF09351.5 EKG20598.1 - 4.5e-29 101.4 0.0 5.4e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) ADH_N PF08240.7 EKG20599.1 - 1.6e-21 76.1 0.6 3e-21 75.2 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG20599.1 - 8.1e-21 73.9 0.3 1.3e-20 73.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EKG20599.1 - 0.0037 17.2 0.1 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EKG20599.1 - 0.0052 16.3 0.1 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 EKG20599.1 - 0.0056 15.8 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EKG20599.1 - 0.013 15.6 0.1 0.031 14.4 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain Shikimate_DH PF01488.15 EKG20599.1 - 0.013 15.5 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EKG20599.1 - 0.018 14.9 2.4 0.024 14.5 0.9 1.6 2 0 0 2 2 2 0 short chain dehydrogenase ELFV_dehydrog PF00208.16 EKG20599.1 - 0.026 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 3HCDH_N PF02737.13 EKG20599.1 - 0.043 13.4 1.3 0.058 13.0 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.15 EKG20599.1 - 0.046 13.6 0.2 0.12 12.3 0.2 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ApbA PF02558.11 EKG20599.1 - 0.048 13.1 0.1 0.077 12.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 EKG20599.1 - 0.069 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Methyltransf_18 PF12847.2 EKG20599.1 - 0.069 13.7 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain ThiF PF00899.16 EKG20599.1 - 0.072 12.9 0.8 0.89 9.3 0.2 2.3 2 0 0 2 2 2 0 ThiF family GFA PF04828.9 EKG20600.1 - 4.8e-10 39.2 0.1 5.6e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EKG20600.1 - 0.061 12.8 0.5 0.1 12.1 0.4 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Alginate_lyase PF05426.7 EKG20602.1 - 1.3e-11 44.4 3.6 2.3e-10 40.3 2.6 2.0 1 1 0 1 1 1 1 Alginate lyase Cutinase PF01083.17 EKG20603.1 - 1.9e-41 141.7 2.4 9.6e-41 139.4 1.6 1.8 1 1 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EKG20603.1 - 0.00012 21.7 0.2 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EKG20603.1 - 0.0013 18.3 0.1 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_9 PF10081.4 EKG20603.1 - 0.0017 17.0 0.0 0.0023 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta-hydrolase family Abhydrolase_3 PF07859.8 EKG20603.1 - 0.0051 16.4 0.3 0.0068 15.9 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EKG20603.1 - 0.0057 16.9 0.0 0.0083 16.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.6 EKG20603.1 - 0.0074 15.7 0.2 0.0087 15.4 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EKG20603.1 - 0.029 14.1 0.6 0.044 13.5 0.4 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG20603.1 - 0.1 12.0 0.1 0.25 10.7 0.0 1.5 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EKG20604.1 - 0.094 12.5 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family NADase_NGA PF07461.6 EKG20604.1 - 0.11 11.1 0.3 0.16 10.6 0.2 1.1 1 0 0 1 1 1 0 Nicotine adenine dinucleotide glycohydrolase (NADase) adh_short PF00106.20 EKG20605.1 - 1.6e-21 76.9 2.2 1.8e-21 76.8 1.5 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG20605.1 - 1.5e-14 54.3 0.0 1.6e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG20605.1 - 7.7e-09 35.4 0.7 9.8e-09 35.1 0.5 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EKG20605.1 - 1.4e-07 31.6 0.1 1.7e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG20605.1 - 4.5e-05 22.9 0.1 5.1e-05 22.8 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PAE PF03283.8 EKG20605.1 - 0.0046 15.6 0.1 0.0059 15.2 0.0 1.1 1 0 0 1 1 1 1 Pectinacetylesterase F420_oxidored PF03807.12 EKG20605.1 - 0.012 16.0 0.1 0.021 15.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.10 EKG20605.1 - 0.017 14.7 0.1 0.022 14.3 0.1 1.2 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 EKG20605.1 - 0.021 14.6 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EKG20605.1 - 0.025 13.4 0.2 0.029 13.2 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EKG20605.1 - 0.12 11.5 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.5 EKG20606.1 - 0.073 12.1 0.0 1 8.4 0.0 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Actin PF00022.14 EKG20607.1 - 1.8e-98 329.5 0.0 2.1e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Actin p450 PF00067.17 EKG20608.1 - 3.4e-55 187.4 0.0 4.4e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CENP-X PF09415.5 EKG20608.1 - 0.015 15.0 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X zf-RING_2 PF13639.1 EKG20610.1 - 9.6e-15 54.1 5.2 1.5e-14 53.5 3.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKG20610.1 - 2.2e-08 34.1 0.4 3.8e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKG20610.1 - 1.4e-07 31.0 3.8 2.2e-07 30.4 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG20610.1 - 3.7e-06 26.8 5.0 5.9e-06 26.2 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG20610.1 - 5.3e-06 26.0 2.2 8.2e-06 25.4 1.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG20610.1 - 2.9e-05 23.6 1.5 5.2e-05 22.8 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EKG20610.1 - 0.00045 19.9 1.4 0.00091 19.0 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EKG20610.1 - 0.019 14.5 3.1 0.033 13.7 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EKG20610.1 - 0.28 11.1 2.6 0.48 10.4 1.8 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EKG20610.1 - 0.36 10.5 2.6 0.6 9.8 1.8 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.1 EKG20610.1 - 1.8 8.1 7.5 4.3 6.9 0.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Neur_chan_memb PF02932.11 EKG20610.1 - 5.1 6.9 5.7 1.2e+02 2.4 4.0 2.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HATPase_c PF02518.21 EKG20612.1 - 3.1e-19 68.7 0.1 7.3e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EKG20612.1 - 1.3e-11 44.2 0.1 1.8e-10 40.6 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EKG20612.1 - 2.9e-09 37.2 1.0 1e-07 32.2 0.2 2.8 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.19 EKG20612.1 - 3e-09 36.8 0.0 0.0031 17.4 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain adh_short_C2 PF13561.1 EKG20613.1 - 1.9e-22 80.2 0.0 3e-21 76.2 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EKG20613.1 - 1.7e-19 69.7 0.0 4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ketoacyl-synt PF00109.21 EKG20613.1 - 1.5e-18 67.1 0.0 3.3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG20613.1 - 2.6e-11 43.3 0.0 6.3e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EKG20613.1 - 3.1e-05 23.9 0.0 7.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG20613.1 - 0.022 14.4 0.0 0.066 12.8 0.0 1.8 1 0 0 1 1 1 0 KR domain Acyl_transf_1 PF00698.16 EKG20614.1 - 6.6e-82 275.3 0.4 2.4e-81 273.5 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EKG20614.1 - 7.8e-37 125.3 0.0 1.7e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EKG20614.1 - 6.8e-33 112.2 1.7 3.7e-32 109.8 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EKG20614.1 - 1.1e-23 83.5 0.0 3.2e-23 81.9 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MCRS_N PF13325.1 EKG20614.1 - 0.096 12.1 0.1 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Brr6_like_C_C PF10104.4 EKG20615.1 - 2.5e-43 146.8 5.9 3.2e-43 146.4 4.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain ATP-synt_8 PF00895.15 EKG20615.1 - 0.007 16.5 0.2 0.026 14.7 0.1 2.0 1 0 0 1 1 1 1 ATP synthase protein 8 TRP PF06011.7 EKG20615.1 - 0.021 13.4 0.2 0.032 12.8 0.2 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel WGR PF05406.10 EKG20616.1 - 0.049 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 WGR domain Transp_cyt_pur PF02133.10 EKG20618.1 - 7.4e-88 295.0 30.3 8.5e-88 294.8 21.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 EKG20619.1 - 1.3e-06 27.4 1.3 1.7e-06 27.0 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 EKG20620.1 - 9.8e-52 175.5 0.6 6.7e-50 169.5 0.2 2.7 2 1 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family Abhydrolase_6 PF12697.2 EKG20620.1 - 1.4e-36 126.4 2.8 2.2e-36 125.8 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG20620.1 - 1.5e-19 70.4 0.0 2.2e-16 60.1 0.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG20620.1 - 3.4e-15 56.0 0.3 2.6e-14 53.2 0.2 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EKG20620.1 - 5.9e-09 35.7 0.4 5.4e-06 26.1 0.3 2.3 1 1 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.8 EKG20620.1 - 0.0011 18.6 0.1 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_4 PF08386.5 EKG20620.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EKG20620.1 - 0.0064 16.3 0.0 0.091 12.6 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EKG20620.1 - 0.028 12.9 0.0 0.044 12.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family Cyt-b5 PF00173.23 EKG20621.1 - 1.8e-10 40.4 0.1 2.7e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidohydro_1 PF01979.15 EKG20622.1 - 1.1e-09 38.3 0.0 2.6e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG20622.1 - 3e-06 27.4 2.2 5e-06 26.7 1.5 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG20622.1 - 0.0044 16.2 0.4 0.016 14.4 0.1 1.7 1 1 1 2 2 2 2 Amidohydrolase family Oxidored_FMN PF00724.15 EKG20624.1 - 2.9e-89 299.4 0.0 3.6e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase_3 PF14832.1 EKG20625.1 - 6.9e-52 175.0 0.3 7.7e-52 174.9 0.2 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme ADH_zinc_N_2 PF13602.1 EKG20626.1 - 0.0043 17.9 0.0 0.0081 17.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pribosyltran PF00156.22 EKG20626.1 - 0.063 13.0 0.1 0.095 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain ADH_zinc_N PF00107.21 EKG20626.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG20627.1 - 1e-06 28.4 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.4 EKG20628.1 - 1.3e-15 57.2 0.0 2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EKG20628.1 - 4.5e-07 30.4 0.0 1.2e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EKG20628.1 - 0.0006 19.8 2.2 0.0006 19.8 1.5 2.2 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.9 EKG20628.1 - 0.0011 18.4 0.0 0.012 14.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EKG20628.1 - 0.0035 17.0 0.0 0.0062 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG20628.1 - 0.0043 17.5 0.0 0.012 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG20628.1 - 0.0075 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EKG20628.1 - 0.014 16.1 0.0 0.039 14.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EKG20628.1 - 0.048 13.6 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EKG20628.1 - 0.066 13.7 0.0 0.16 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Lycopene_cycl PF05834.7 EKG20629.1 - 0.00036 19.5 0.1 0.00046 19.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EKG20629.1 - 0.0012 18.0 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EKG20629.1 - 0.002 17.2 0.2 0.003 16.6 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EKG20629.1 - 0.082 11.7 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyocin_S PF06958.7 EKG20629.1 - 2.7 8.3 6.5 2.2 8.6 3.5 1.5 1 1 0 1 1 1 0 S-type Pyocin Abhydrolase_6 PF12697.2 EKG20633.1 - 0.0065 16.3 0.0 0.0066 16.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox_3 PF13738.1 EKG20635.1 - 1.3e-09 38.4 0.0 1.4e-09 38.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG20635.1 - 4.5e-06 25.8 0.0 5.1e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EKG20635.1 - 0.0066 14.7 0.0 0.0066 14.7 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Amino_oxidase PF01593.19 EKG20636.1 - 4.3e-24 85.3 2.7 1.1e-15 57.6 0.2 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase ABC_membrane_3 PF13748.1 EKG20638.1 - 0.049 12.6 0.0 0.065 12.2 0.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region Polysacc_deac_1 PF01522.16 EKG20639.1 - 1.5e-15 56.9 0.0 3.1e-14 52.6 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF3783 PF12646.2 EKG20639.1 - 0.052 13.2 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) p450 PF00067.17 EKG20640.1 - 2.2e-29 102.2 0.1 2.7e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Reo_sigmaC PF04582.7 EKG20641.1 - 1.1e-08 34.7 39.2 4.2e-06 26.1 3.8 5.0 1 1 4 5 5 5 3 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EKG20641.1 - 4.4e-05 23.6 51.0 0.0043 17.1 0.9 6.7 3 2 2 6 6 6 4 Fibrinogen alpha/beta chain family IncA PF04156.9 EKG20641.1 - 0.0037 16.8 15.7 0.0037 16.8 10.9 7.8 1 1 6 7 7 7 4 IncA protein DUF2435 PF10363.4 EKG20641.1 - 0.019 14.8 2.7 0.081 12.8 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2435) AAA_13 PF13166.1 EKG20641.1 - 4.5 5.6 77.3 0.24 9.7 20.9 4.1 1 1 3 4 4 4 0 AAA domain TFIIF_alpha PF05793.7 EKG20642.1 - 0.069 11.5 47.0 0.12 10.7 32.6 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 EKG20642.1 - 1.1 6.8 8.8 1.8 6.1 6.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2867 PF11066.3 EKG20643.1 - 0.11 12.2 1.4 0.11 12.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2867) PKK PF12474.3 EKG20644.1 - 2.4 7.8 9.6 0.23 11.1 2.9 1.9 2 0 0 2 2 2 0 Polo kinase kinase Arginase PF00491.16 EKG20646.1 - 8.2e-19 67.9 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Arginase family Sulf_transp PF04143.9 EKG20646.1 - 1.1 9.3 4.4 1.9 8.6 0.3 2.6 2 0 0 2 2 2 0 Sulphur transport Fungal_trans PF04082.13 EKG20647.1 - 4.4e-23 81.4 0.0 5.8e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MOSC PF03473.12 EKG20648.1 - 2.2e-12 46.5 0.0 3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 MOSC domain Peptidase_M28 PF04389.12 EKG20649.1 - 7.1e-18 64.9 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EKG20649.1 - 1.4e-17 63.4 0.0 2.1e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EKG20649.1 - 0.0005 19.7 0.1 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EKG20649.1 - 0.007 15.8 0.0 0.018 14.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Abhydrolase_5 PF12695.2 EKG20650.1 - 7.2e-07 29.0 0.0 2.2e-06 27.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EKG20650.1 - 4.1e-06 26.5 0.0 7.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EKG20650.1 - 1e-05 25.5 0.1 2e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EKG20650.1 - 0.00018 20.9 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EKG20650.1 - 0.0013 17.8 0.2 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 EKG20650.1 - 0.0068 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EKG20650.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EKG20650.1 - 0.08 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EKG20650.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) TFIIA PF03153.8 EKG20651.1 - 1.1 9.1 10.9 1.4 8.7 7.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mitofilin PF09731.4 EKG20651.1 - 1.4 7.4 10.3 1.8 7.0 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.4 EKG20651.1 - 1.9 6.6 10.1 2.2 6.4 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 EKG20651.1 - 2 6.9 16.5 2.4 6.7 11.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DDHD PF02862.12 EKG20651.1 - 3 7.5 6.4 4.6 6.9 4.4 1.2 1 0 0 1 1 1 0 DDHD domain Herpes_TAF50 PF03326.8 EKG20651.1 - 7.1 5.4 18.8 10 4.9 13.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Rifin_STEVOR PF02009.11 EKG20651.1 - 8.4 5.9 14.0 11 5.5 9.7 1.2 1 0 0 1 1 1 0 Rifin/stevor family Pro_isomerase PF00160.16 EKG20652.1 - 1.5e-45 155.1 0.0 2.7e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EKG20652.1 - 4.2e-10 39.2 0.2 1.4e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EKG20652.1 - 0.01 15.7 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 0 U-box domain Prp19_bind PF06991.6 EKG20653.1 - 6.3e-47 160.1 32.5 6.3e-47 160.1 22.5 2.1 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain PQ-loop PF04193.9 EKG20654.1 - 2.7e-17 62.0 0.8 2.7e-17 62.0 0.6 2.5 3 0 0 3 3 3 1 PQ loop repeat DUF1275 PF06912.6 EKG20654.1 - 0.0012 18.0 2.1 0.0019 17.4 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3902 PF13042.1 EKG20654.1 - 0.18 11.0 6.1 0.043 13.0 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) TMEM238 PF15125.1 EKG20654.1 - 7 6.6 6.8 2.2 8.2 0.3 2.6 2 1 0 2 2 2 0 TMEM238 protein family Spb1_C PF07780.7 EKG20655.1 - 6e-74 248.1 29.7 6e-74 248.1 20.6 4.1 2 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EKG20655.1 - 1.6e-55 186.9 13.8 1.6e-55 186.9 9.5 4.6 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EKG20655.1 - 3.5e-55 186.7 0.5 2.9e-54 183.7 0.0 2.4 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF1569 PF07606.6 EKG20655.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1569) YgaB PF14182.1 EKG20655.1 - 1.6 9.0 16.1 0.21 11.8 7.1 2.7 2 0 0 2 2 2 0 YgaB-like protein Rep_fac-A_3 PF08661.6 EKG20657.1 - 2.3e-29 101.4 0.1 2.6e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF2470 PF10615.4 EKG20657.1 - 0.14 12.4 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) GTP_EFTU PF00009.22 EKG20658.1 - 5.2e-21 74.9 0.0 8.7e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EKG20658.1 - 1.1e-14 54.3 0.1 2.7e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EKG20658.1 - 4.3e-11 42.7 3.4 2.1e-10 40.5 0.6 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EKG20658.1 - 0.013 15.0 1.3 0.65 9.4 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 EKG20658.1 - 0.042 13.4 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EKG20658.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 EKG20658.1 - 0.12 12.8 0.3 0.82 10.1 0.2 2.3 1 1 0 1 1 1 0 Miro-like protein DUF2363 PF10155.4 EKG20659.1 - 3.5e-07 30.1 0.0 5.2e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2363) Aldo_ket_red PF00248.16 EKG20660.1 - 4.8e-54 183.0 0.0 5.5e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.15 EKG20661.1 - 7.3e-09 35.7 24.6 3.5e-06 27.0 0.4 2.6 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EKG20661.1 - 6.6e-06 26.3 0.5 6.6e-06 26.3 0.3 2.8 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EKG20661.1 - 0.0059 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter DUF914 PF06027.7 EKG20661.1 - 0.0062 15.4 1.5 0.03 13.1 1.0 2.2 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) DUF1469 PF07332.6 EKG20661.1 - 0.24 11.1 5.6 0.44 10.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) TPT PF03151.11 EKG20661.1 - 0.76 9.4 14.4 1.4 8.5 0.9 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family Sugar_tr PF00083.19 EKG20662.1 - 6.3e-67 226.0 12.7 7.5e-67 225.8 8.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter PhyH PF05721.8 EKG20663.1 - 6.2e-09 36.2 0.1 1.3e-08 35.1 0.1 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EKG20663.1 - 0.00013 20.5 0.1 0.15 10.5 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) Trehalase PF01204.13 EKG20667.1 - 6.3e-127 424.3 0.0 1.7e-126 422.8 0.0 1.6 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 EKG20667.1 - 0.0014 17.4 0.3 0.013 14.2 0.1 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase SET PF00856.23 EKG20668.1 - 0.0019 18.5 0.0 0.094 13.0 0.0 2.4 2 0 0 2 2 2 2 SET domain Oxidored_FMN PF00724.15 EKG20669.1 - 3.4e-50 170.9 0.0 4.4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GTP_cyclohydro2 PF00925.15 EKG20671.1 - 4e-58 195.3 0.1 1.1e-52 177.6 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Chitin_bind_3 PF03067.10 EKG20672.1 - 6e-05 23.3 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Chitin binding domain Fmp27 PF10344.4 EKG20673.1 - 1.9e-203 677.7 0.0 2.8e-203 677.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EKG20673.1 - 3e-166 553.8 2.5 3.7e-166 553.5 0.0 2.3 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EKG20673.1 - 2.6e-151 504.2 7.3 2.6e-151 504.2 5.0 2.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EKG20673.1 - 2.6e-55 186.6 0.1 8.7e-55 184.9 0.0 2.0 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EKG20673.1 - 9.4e-54 181.4 0.0 2e-53 180.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EKG20673.1 - 1.4e-30 105.7 0.0 4.4e-30 104.1 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain WW PF00397.21 EKG20674.1 - 1.8e-05 24.4 2.4 6.8e-05 22.6 1.6 2.1 1 0 0 1 1 1 1 WW domain PAT1 PF09770.4 EKG20674.1 - 1.4 7.0 15.3 1.5 6.9 10.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PQ-loop PF04193.9 EKG20675.1 - 2.7e-37 126.1 12.6 2e-18 65.6 1.0 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EKG20675.1 - 0.0038 17.0 3.5 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Pyr_redox_2 PF07992.9 EKG20678.1 - 3.1e-27 95.7 0.0 1.2e-16 61.2 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG20678.1 - 5e-13 49.2 1.7 1e-11 45.0 0.0 3.1 3 2 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG20678.1 - 0.0011 19.0 1.3 1.7 8.6 0.1 3.4 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 4HBT_3 PF13622.1 EKG20679.1 - 2.2e-49 168.5 0.2 2.7e-49 168.1 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EKG20679.1 - 7.8e-07 28.7 0.8 0.00021 20.8 0.2 3.1 2 2 1 3 3 3 2 Acyl-CoA thioesterase Cyclin PF08613.6 EKG20680.1 - 8e-16 58.7 0.0 1.2e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EKG20680.1 - 0.00016 21.2 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L18e PF00828.14 EKG20681.1 - 4.1e-15 56.2 0.1 6.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 CBM_48 PF02922.13 EKG20681.1 - 0.095 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Pyridoxal_deC PF00282.14 EKG20682.1 - 2.5e-102 342.1 0.0 3.3e-102 341.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EKG20682.1 - 0.0015 17.5 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SPRY PF00622.23 EKG20683.1 - 0.0025 17.9 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 SPRY domain Bystin PF05291.6 EKG20684.1 - 2.1e-124 414.4 0.0 2.8e-124 413.9 0.0 1.1 1 0 0 1 1 1 1 Bystin p450 PF00067.17 EKG20687.1 - 2.3e-10 39.5 0.0 2.9e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1749 PF08538.5 EKG20688.1 - 1.8e-37 128.8 0.0 2e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) PhyH PF05721.8 EKG20689.1 - 3.9e-19 69.5 0.1 5.4e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Vault PF01505.13 EKG20689.1 - 0.037 14.0 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Major Vault Protein repeat NDUF_B7 PF05676.8 EKG20690.1 - 8.4e-32 108.3 3.7 1.1e-31 108.0 2.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EKG20690.1 - 0.024 14.4 2.8 0.032 14.0 1.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DSPn PF14671.1 EKG20691.1 - 8.9e-44 148.8 0.0 4.3e-40 136.9 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EKG20691.1 - 5.5e-16 58.3 0.0 9.2e-15 54.3 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKG20691.1 - 4.4e-06 26.2 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3439 PF11921.3 EKG20691.1 - 0.016 14.9 2.5 0.037 13.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Adeno_E1B_55K_N PF04623.7 EKG20691.1 - 0.099 13.1 0.6 0.33 11.4 0.4 1.9 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus SET PF00856.23 EKG20692.1 - 0.039 14.2 0.0 0.084 13.1 0.0 1.8 1 1 0 1 1 1 0 SET domain Fungal_trans PF04082.13 EKG20693.1 - 5e-28 97.6 0.6 9.8e-28 96.7 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG20693.1 - 6e-10 38.8 10.8 1e-09 38.1 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC144C PF14915.1 EKG20693.1 - 0.024 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DASH_Spc34 PF08657.5 EKG20693.1 - 0.031 13.9 1.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Spc34 Macoilin PF09726.4 EKG20693.1 - 1.7 6.8 6.1 0.49 8.6 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein AAA PF00004.24 EKG20695.1 - 3.7e-17 62.7 0.0 6.4e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EKG20695.1 - 7.4e-06 25.4 0.3 0.012 15.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 EKG20695.1 - 1.5e-05 25.1 0.0 3.7e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EKG20695.1 - 3.2e-05 23.6 0.7 0.057 13.0 0.1 2.3 1 1 1 2 2 2 2 NACHT domain AAA_16 PF13191.1 EKG20695.1 - 0.0001 22.3 3.0 0.009 16.0 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EKG20695.1 - 0.004 16.8 0.2 0.015 15.0 0.0 1.9 2 1 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EKG20695.1 - 0.012 15.5 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKG20695.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EKG20695.1 - 0.025 13.5 0.0 0.049 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EKG20695.1 - 0.035 14.0 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EKG20695.1 - 0.044 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 EKG20695.1 - 0.045 13.9 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EKG20695.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Urease_alpha PF00449.15 EKG20695.1 - 0.083 13.0 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain D-ser_dehydrat PF14031.1 EKG20697.1 - 0.01 16.0 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Putative serine dehydratase domain CorA PF01544.13 EKG20698.1 - 1.4e-09 37.4 4.7 4e-09 35.9 3.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DAD PF02109.11 EKG20699.1 - 0.075 13.0 0.3 0.13 12.3 0.2 1.3 1 0 0 1 1 1 0 DAD family p450 PF00067.17 EKG20700.1 - 1.7e-51 175.1 0.0 2e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG20701.1 - 5.8e-05 21.8 0.0 7.1e-05 21.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 EKG20702.1 - 4e-105 352.5 0.4 5e-105 352.2 0.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EKG20702.1 - 0.027 14.2 0.2 0.087 12.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EKG20702.1 - 0.039 13.5 2.5 0.071 12.6 0.1 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold Flavodoxin_1 PF00258.20 EKG20706.1 - 7.4e-12 45.4 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EKG20706.1 - 7.3e-06 25.5 0.7 0.023 14.1 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EKG20706.1 - 0.0053 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NO_synthase PF02898.10 EKG20707.1 - 3.8e-05 22.5 1.5 9.2e-05 21.2 0.8 1.7 1 1 1 2 2 2 1 Nitric oxide synthase, oxygenase domain Cu-oxidase_3 PF07732.10 EKG20708.1 - 5.7e-33 113.1 1.6 1.1e-31 109.0 0.7 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG20708.1 - 1.6e-20 73.0 4.1 5.9e-18 64.7 0.3 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EKG20708.1 - 5.5e-17 62.1 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EKG20709.1 - 6.2e-22 77.5 0.8 9.1e-22 77.0 0.6 1.2 1 0 0 1 1 1 1 Multicopper oxidase Dioxygenase_C PF00775.16 EKG20711.1 - 6.1e-50 169.0 0.0 8.6e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EKG20711.1 - 2.1e-16 59.6 0.0 5.2e-16 58.3 0.0 1.7 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EKG20711.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DHquinase_II PF01220.14 EKG20712.1 - 6.9e-59 197.1 0.0 7.8e-59 197.0 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II ThiF PF00899.16 EKG20712.1 - 0.1 12.4 0.1 4.6 7.0 0.0 2.1 2 0 0 2 2 2 0 ThiF family Inositol_P PF00459.20 EKG20713.1 - 1.7e-74 250.5 0.0 1.8e-72 243.9 0.0 2.0 1 1 0 1 1 1 1 Inositol monophosphatase family Shikimate_DH PF01488.15 EKG20714.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EKG20715.1 - 1.7e-126 422.4 29.3 1.9e-126 422.2 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20715.1 - 1.8e-18 66.3 39.1 1.8e-18 66.3 27.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.17 EKG20716.1 - 8e-26 90.9 0.2 1.2e-25 90.3 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EKG20716.1 - 4.5e-16 58.6 0.0 1e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EKG20716.1 - 0.0026 18.0 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EKG20718.1 - 2.7e-15 55.9 0.0 4.2e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG20718.1 - 4.7e-07 29.6 10.3 7.4e-07 28.9 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 EKG20719.1 - 5.3e-44 150.5 0.0 9.5e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EKG20719.1 - 8.6e-20 70.5 0.1 2.3e-19 69.2 0.1 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EKG20719.1 - 5.1e-16 58.9 0.0 9.2e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EKG20719.1 - 5.8e-11 42.6 0.3 1.4e-10 41.3 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.1 EKG20719.1 - 0.056 13.4 0.2 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ThiF PF00899.16 EKG20719.1 - 0.15 11.8 0.5 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 ThiF family AAA_18 PF13238.1 EKG20719.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EKG20720.1 - 2e-12 46.5 0.1 3.5e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EKG20721.1 - 6.1e-118 394.2 28.7 6.9e-118 394.0 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20721.1 - 5.5e-27 94.4 70.4 2.2e-23 82.5 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.1 EKG20722.1 - 2.3e-33 115.9 0.0 2.7e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG20722.1 - 2e-29 102.6 1.1 2.7e-29 102.2 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG20722.1 - 3.6e-12 46.3 0.5 5.3e-12 45.7 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG20722.1 - 0.00031 20.2 0.0 0.00057 19.3 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EKG20722.1 - 0.0022 17.6 0.1 0.0033 17.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 EKG20722.1 - 0.0088 16.0 0.4 0.017 15.1 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EKG20722.1 - 0.019 14.3 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.1 EKG20722.1 - 0.064 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EKG20722.1 - 0.085 13.4 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.19 EKG20722.1 - 0.088 11.6 1.7 0.28 10.0 0.7 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG20722.1 - 0.11 12.5 0.1 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Polysacc_synt_2 PF02719.10 EKG20722.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Bac_rhamnosid PF05592.6 EKG20723.1 - 9.1e-57 192.4 0.0 1.5e-36 125.7 0.0 3.1 1 1 2 3 3 3 3 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EKG20723.1 - 5.5e-08 32.5 0.0 8.5e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Amidohydro_1 PF01979.15 EKG20724.1 - 1.4e-42 146.5 0.3 1.7e-42 146.2 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EKG20724.1 - 2.9e-10 39.9 3.8 8.3e-09 35.1 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EKG20724.1 - 3.9e-06 27.0 0.1 0.0033 17.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EKG20724.1 - 9.2e-06 25.3 0.0 3.2e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EKG20724.1 - 9.4e-06 24.7 0.1 1.4e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase tRNA_int_endo_N PF02778.9 EKG20724.1 - 0.002 17.6 0.0 0.016 14.7 0.0 2.4 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain DUF676 PF05057.9 EKG20726.1 - 5.2e-39 133.8 0.0 2e-26 92.6 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EKG20726.1 - 0.0043 16.8 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EKG20726.1 - 0.0046 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EKG20726.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Fumble PF03630.9 EKG20727.1 - 1.2e-91 307.1 0.0 1.1e-90 303.9 0.0 1.9 1 1 0 1 1 1 1 Fumble Actin PF00022.14 EKG20728.1 - 9.1e-22 77.0 0.0 4.5e-20 71.4 0.0 2.7 2 1 0 2 2 2 1 Actin cNMP_binding PF00027.24 EKG20729.1 - 1.2e-37 127.5 0.2 3.3e-20 71.7 0.0 5.2 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain Patatin PF01734.17 EKG20729.1 - 1.6e-17 64.0 6.8 3.6e-17 62.9 2.5 3.0 2 1 0 2 2 2 1 Patatin-like phospholipase SUN PF03856.8 EKG20732.1 - 1.2e-89 299.8 15.0 1.7e-89 299.4 10.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Abhydrolase_5 PF12695.2 EKG20734.1 - 2.4e-13 50.0 0.0 5.1e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG20734.1 - 1.3e-11 44.8 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EKG20734.1 - 1.7e-05 24.1 0.0 0.00025 20.3 0.1 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EKG20734.1 - 0.00011 21.6 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EKG20734.1 - 0.0007 19.3 0.1 0.0015 18.2 0.0 1.6 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1100 PF06500.6 EKG20734.1 - 0.039 12.5 0.0 0.051 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.7 EKG20734.1 - 0.15 10.4 0.1 0.29 9.5 0.1 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Amidase PF01425.16 EKG20735.1 - 0.00042 19.2 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 Amidase AIRC PF00731.15 EKG20735.1 - 0.32 10.2 2.0 0.44 9.8 0.9 1.6 1 1 0 1 1 1 0 AIR carboxylase AhpC-TSA_2 PF13911.1 EKG20736.1 - 1.5e-17 63.5 0.0 2.5e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EKG20736.1 - 0.077 12.6 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family ADH_N PF08240.7 EKG20737.1 - 4.6e-28 97.1 0.7 1.1e-27 95.9 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG20737.1 - 4.8e-19 68.1 0.1 8.3e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EKG20737.1 - 0.012 14.9 0.2 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EKG20737.1 - 0.03 14.1 0.4 0.4 10.5 0.3 2.2 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.12 EKG20737.1 - 0.036 14.4 0.1 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EKG20737.1 - 0.055 13.7 0.1 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EKG20737.1 - 0.072 13.1 0.2 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Gp_dh_N PF00044.19 EKG20737.1 - 0.094 12.6 0.4 7.3 6.5 0.1 2.4 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 EKG20738.1 - 1e-64 218.5 0.0 1.4e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG20738.1 - 1.3e-33 116.3 1.7 2.2e-33 115.5 1.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG20738.1 - 0.00092 18.2 0.3 0.045 12.6 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG20738.1 - 0.0012 17.7 0.0 1 8.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EKG20738.1 - 0.037 13.1 0.3 0.11 11.5 0.0 1.8 3 0 0 3 3 3 0 Thi4 family NAD_binding_8 PF13450.1 EKG20738.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EKG20738.1 - 0.055 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein E1-E2_ATPase PF00122.15 EKG20739.1 - 5.5e-66 221.9 1.0 1e-65 221.0 0.7 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG20739.1 - 1.8e-33 115.6 4.9 1.8e-33 115.6 3.4 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG20739.1 - 1.3e-28 100.9 0.1 3.5e-24 86.4 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG20739.1 - 1.5e-17 63.3 0.0 3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EKG20739.1 - 6.1e-15 54.4 0.3 4.2e-14 51.7 0.0 2.6 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EKG20739.1 - 1.2e-13 51.6 0.0 2.9e-13 50.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG20739.1 - 0.0001 21.9 0.2 0.0007 19.2 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4231 PF14015.1 EKG20739.1 - 0.49 10.4 12.4 2.1 8.3 0.4 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) SieB PF14163.1 EKG20739.1 - 8.3 5.9 10.4 0.076 12.5 0.5 2.5 3 0 0 3 3 3 0 Superinfection exclusion protein B Tubulin PF00091.20 EKG20742.1 - 2.6e-48 164.6 0.0 6.2e-48 163.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKG20742.1 - 2.9e-46 156.5 0.5 6.3e-46 155.5 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EKG20742.1 - 0.0032 16.9 0.0 0.0067 15.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Vps23_core PF09454.5 EKG20743.1 - 1.2e-20 72.9 0.0 2.1e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain AIRC PF00731.15 EKG20743.1 - 0.078 12.2 0.6 0.12 11.5 0.4 1.2 1 0 0 1 1 1 0 AIR carboxylase Aminotran_5 PF00266.14 EKG20744.1 - 5e-97 324.9 0.0 6.3e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EKG20744.1 - 3.4e-07 29.7 0.0 5.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EKG20744.1 - 1.3e-05 24.4 0.0 3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EKG20744.1 - 0.0067 14.9 0.0 0.0097 14.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EKG20744.1 - 0.013 13.8 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme zf-C4 PF00105.13 EKG20744.1 - 0.11 12.7 0.7 0.29 11.3 0.5 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) BAR PF03114.13 EKG20745.1 - 8.3e-63 211.9 8.1 1.1e-62 211.5 5.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EKG20745.1 - 2.4e-14 52.4 0.1 4.6e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG20745.1 - 1.3e-10 40.6 0.1 2.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EKG20745.1 - 2.7e-09 36.3 0.0 7.5e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AHS1 PF02682.11 EKG20745.1 - 0.026 14.0 0.6 0.055 12.9 0.4 1.5 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 TMPIT PF07851.8 EKG20745.1 - 0.37 9.8 4.0 0.14 11.2 0.5 1.8 1 1 1 2 2 2 0 TMPIT-like protein Maf1 PF09174.5 EKG20746.1 - 5.4e-61 205.5 0.0 7.3e-61 205.1 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 EKG20747.1 - 1.2e-53 180.6 2.4 1.4e-53 180.3 1.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EKG20747.1 - 0.1 11.8 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) Aldo_ket_red PF00248.16 EKG20748.1 - 1e-13 50.7 0.0 1.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans_2 PF11951.3 EKG20750.1 - 2.3e-06 26.5 1.1 2.3e-06 26.4 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gryzun-like PF12742.2 EKG20750.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Rtf2 PF04641.7 EKG20752.1 - 3.2e-52 177.2 1.9 4e-52 176.9 1.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EKG20752.1 - 0.0029 17.0 0.0 0.07 12.6 0.0 2.3 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EKG20752.1 - 0.0074 15.9 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger GFO_IDH_MocA PF01408.17 EKG20753.1 - 1.6e-23 83.4 0.1 2.9e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EKG20753.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CoA_binding PF02629.14 EKG20753.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain F420_oxidored PF03807.12 EKG20753.1 - 0.047 14.1 0.0 0.19 12.1 0.0 2.1 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans_2 PF11951.3 EKG20754.1 - 1.1e-15 57.1 5.6 1.4e-15 56.7 3.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG20754.1 - 0.00013 21.8 17.1 0.00026 20.8 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EKG20755.1 - 0.15 10.8 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Amidase Amidase PF01425.16 EKG20757.1 - 9.4e-24 84.0 0.0 1.3e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EKG20758.1 - 8.2e-31 106.9 18.5 8.2e-31 106.9 12.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF21 PF01595.15 EKG20758.1 - 3.2 6.9 6.9 0.27 10.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF21 Epimerase PF01370.16 EKG20759.1 - 4.9e-15 55.6 0.2 2e-14 53.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG20759.1 - 3.3e-12 45.6 0.0 4.9e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EKG20759.1 - 5.5e-09 36.2 1.3 2e-08 34.4 0.9 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EKG20759.1 - 1.9e-06 27.8 2.6 1.9e-06 27.8 1.8 1.6 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EKG20759.1 - 8.5e-06 25.1 0.4 3.2e-05 23.2 0.3 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EKG20759.1 - 1.5e-05 24.1 0.1 0.034 13.0 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EKG20759.1 - 0.33 9.8 1.3 1.8 7.3 0.8 1.9 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Lipase_GDSL_2 PF13472.1 EKG20761.1 - 2.2e-09 37.7 0.0 5.5e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.2 EKG20762.1 - 6.4e-06 25.8 0.0 2.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKG20762.1 - 1.2e-05 24.8 0.0 0.00097 18.7 0.0 2.6 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EKG20762.1 - 0.066 12.8 0.0 4.5 7.0 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2502 PF10697.4 EKG20762.1 - 0.16 12.0 0.2 0.28 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) DUF4080 PF13311.1 EKG20763.1 - 0.048 13.7 0.1 0.087 12.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4080) Glyco_hydro_3 PF00933.16 EKG20765.1 - 1.4e-86 290.1 0.0 2.3e-86 289.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG20765.1 - 8e-66 221.8 0.0 2.6e-65 220.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG20765.1 - 3e-22 78.3 1.1 9.7e-22 76.6 0.8 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EKG20765.1 - 3.7e-07 29.8 0.1 9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Glyco_hydro_16 PF00722.16 EKG20766.1 - 7.2e-11 41.7 0.5 3.6e-10 39.4 0.3 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Cutinase PF01083.17 EKG20767.1 - 2.4e-50 170.7 3.4 2.8e-50 170.5 2.4 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EKG20767.1 - 0.0001 21.8 0.2 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.15 EKG20767.1 - 0.00021 21.6 0.0 0.00033 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EKG20767.1 - 0.00071 19.1 0.1 0.00091 18.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG20767.1 - 0.0015 18.2 0.2 0.0019 17.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EKG20767.1 - 0.0024 17.2 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EKG20767.1 - 0.003 17.4 0.1 0.0039 17.1 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EKG20767.1 - 0.0058 16.4 0.0 0.035 13.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.8 EKG20767.1 - 0.0084 15.7 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EKG20767.1 - 0.028 14.0 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EKG20767.1 - 0.089 12.2 0.3 0.18 11.2 0.1 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAMBI PF06211.7 EKG20769.1 - 0.098 12.6 5.1 0.12 12.3 3.6 1.1 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Inhibitor_I68 PF10468.4 EKG20769.1 - 0.69 10.1 7.9 5.8 7.1 1.6 2.2 1 1 1 2 2 2 0 Carboxypeptidase inhibitor I68 p450 PF00067.17 EKG20771.1 - 1.8e-42 145.4 0.0 2.5e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EKG20772.1 - 7e-32 110.5 0.8 8.2e-32 110.3 0.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20772.1 - 7.6e-11 41.3 6.6 9.6e-11 40.9 4.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG20772.1 - 0.0056 14.9 1.1 0.0069 14.6 0.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1689 PF07954.6 EKG20772.1 - 0.19 11.5 0.3 0.41 10.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) ADH_zinc_N PF00107.21 EKG20773.1 - 0.022 14.3 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Ribosomal_L50 PF10501.4 EKG20774.1 - 7.7e-20 70.9 0.0 1.1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S MerR PF00376.18 EKG20774.1 - 0.044 13.3 0.1 0.58 9.7 0.0 2.7 3 0 0 3 3 3 0 MerR family regulatory protein NmrA PF05368.8 EKG20778.1 - 3.2e-21 75.6 0.6 6.9e-21 74.5 0.3 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG20778.1 - 1.2e-15 58.0 2.2 1.7e-15 57.4 1.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EKG20778.1 - 9.7e-07 28.4 0.1 2e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EKG20778.1 - 3.9e-05 22.8 1.2 6.4e-05 22.0 0.8 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DFP PF04127.10 EKG20778.1 - 4e-05 23.2 0.3 4e-05 23.2 0.2 2.1 3 0 0 3 3 3 1 DNA / pantothenate metabolism flavoprotein Semialdhyde_dh PF01118.19 EKG20778.1 - 0.00019 21.7 0.9 0.00084 19.6 0.1 2.4 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EKG20778.1 - 0.00099 19.2 0.2 0.0021 18.1 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain RmlD_sub_bind PF04321.12 EKG20778.1 - 0.0059 15.5 0.3 0.01 14.7 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.15 EKG20778.1 - 0.0069 16.3 2.3 0.0084 16.0 0.5 2.0 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EKG20778.1 - 0.01 14.5 0.2 0.024 13.3 0.2 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1815 PF08844.5 EKG20778.1 - 0.028 14.0 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) F420_oxidored PF03807.12 EKG20778.1 - 0.11 12.9 0.3 0.28 11.6 0.2 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EKG20778.1 - 0.12 11.9 2.4 0.1 12.2 0.5 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EKG20778.1 - 0.15 12.1 1.9 1.7 8.6 0.1 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DXP_reductoisom PF02670.11 EKG20778.1 - 2.3 8.7 5.1 20 5.7 0.2 2.8 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase F-box-like PF12937.2 EKG20779.1 - 1e-05 25.1 0.4 2.7e-05 23.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKG20779.1 - 0.00059 19.4 0.3 0.0013 18.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain DUF3382 PF11862.3 EKG20780.1 - 0.11 12.3 6.2 0.039 13.8 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF3328 PF11807.3 EKG20781.1 - 0.12 12.0 0.8 0.17 11.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF3796 PF12676.2 EKG20781.1 - 0.21 11.8 3.4 0.33 11.1 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF3632 PF12311.3 EKG20783.1 - 5.5e-35 120.8 2.3 6.9e-35 120.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Ribonuclease PF00545.15 EKG20784.1 - 0.0026 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 ribonuclease Crystall PF00030.14 EKG20785.1 - 0.00019 21.2 0.1 0.00039 20.2 0.1 1.6 1 1 0 1 1 1 1 Beta/Gamma crystallin Crystall_3 PF08964.5 EKG20785.1 - 0.0089 15.7 0.1 0.017 14.7 0.0 1.6 1 1 1 2 2 2 2 Beta/Gamma crystallin ABC_tran PF00005.22 EKG20786.1 - 1.2e-32 113.1 0.0 2.2e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EKG20786.1 - 5.4e-22 78.4 0.9 5.4e-22 78.4 0.6 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.1 EKG20786.1 - 0.00032 20.7 0.2 0.00067 19.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EKG20786.1 - 0.00093 18.4 0.0 0.016 14.4 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG20786.1 - 0.0012 18.9 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EKG20786.1 - 0.0049 16.7 0.9 0.026 14.4 0.1 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EKG20786.1 - 0.0059 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKG20786.1 - 0.0086 16.2 0.0 0.024 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EKG20786.1 - 0.038 13.4 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EKG20786.1 - 0.046 14.5 0.2 0.18 12.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EKG20786.1 - 0.049 13.1 0.8 0.14 11.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.12 EKG20786.1 - 0.067 12.9 0.7 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EKG20786.1 - 0.084 12.5 0.3 3.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EKG20786.1 - 0.086 12.8 0.3 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EKG20786.1 - 0.11 11.9 0.1 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Abhydrolase_3 PF07859.8 EKG20787.1 - 6.2e-46 156.6 0.0 4.9e-45 153.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG20787.1 - 1.2e-07 30.8 0.6 3.1e-07 29.5 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EKG20787.1 - 6.6e-06 25.9 0.0 8.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG20787.1 - 0.0084 15.3 0.0 0.4 9.8 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family AXE1 PF05448.7 EKG20787.1 - 0.027 12.9 0.1 2.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EKG20787.1 - 0.044 13.2 0.1 0.19 11.1 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EKG20787.1 - 0.072 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase GVQW PF13900.1 EKG20787.1 - 0.12 12.3 1.1 7 6.7 0.0 2.8 3 0 0 3 3 3 0 Putative binding domain DUF2424 PF10340.4 EKG20787.1 - 0.24 9.9 0.0 0.51 8.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Foie-gras_1 PF11817.3 EKG20788.1 - 0.021 14.3 0.3 0.026 14.0 0.2 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 DUF4375 PF14300.1 EKG20788.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Bud13 PF09736.4 EKG20789.1 - 7.9e-46 155.9 8.4 7.9e-46 155.9 5.8 2.7 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF365 PF04033.7 EKG20790.1 - 0.078 12.9 0.2 0.15 12.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF365) Actin PF00022.14 EKG20791.1 - 4.9e-118 393.9 0.0 6.2e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EKG20791.1 - 0.0027 16.3 0.0 0.009 14.6 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein FCH PF00611.18 EKG20792.1 - 3.5e-26 91.2 2.7 6.6e-26 90.3 0.0 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EKG20792.1 - 2.9e-18 65.1 0.2 2.7e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EKG20792.1 - 2e-14 53.0 5.2 3.2e-14 52.3 3.6 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 EKG20792.1 - 3.3e-13 48.8 0.2 1.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EKG20792.1 - 0.0024 17.3 0.1 0.061 12.8 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EKG20792.1 - 0.0028 17.7 0.3 0.044 13.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.11 EKG20792.1 - 0.92 9.6 7.7 1.7 8.8 5.4 1.4 1 0 0 1 1 1 0 C1 domain IncA PF04156.9 EKG20792.1 - 4 7.0 10.6 2.3 7.7 1.2 2.5 2 0 0 2 2 2 0 IncA protein DEAD PF00270.24 EKG20793.1 - 1e-34 119.4 0.1 2.5e-34 118.2 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG20793.1 - 4.8e-23 80.8 0.0 1.2e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EKG20793.1 - 0.0076 16.3 0.1 0.026 14.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain YaaC PF14175.1 EKG20793.1 - 0.012 14.5 0.0 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 YaaC-like Protein AAA_30 PF13604.1 EKG20793.1 - 0.055 13.0 0.2 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain IGPS PF00218.16 EKG20795.1 - 1.7e-97 325.4 0.0 5.3e-97 323.8 0.0 1.8 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EKG20795.1 - 1.5e-51 174.8 0.1 1.1e-48 165.4 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EKG20795.1 - 4.7e-50 169.7 0.0 9.5e-50 168.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EKG20795.1 - 1.8e-06 27.5 0.0 4.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 NanE PF04131.9 EKG20795.1 - 0.061 12.2 0.2 0.22 10.4 0.0 1.9 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Ctr PF04145.10 EKG20796.1 - 6.8e-45 152.6 1.1 9.6e-45 152.1 0.7 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF3169 PF11368.3 EKG20796.1 - 0.12 11.5 2.1 1.9 7.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2244 PF10003.4 EKG20796.1 - 1.6 8.1 4.8 26 4.1 0.0 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF1049 PF06305.6 EKG20796.1 - 9 5.8 8.3 17 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ank_2 PF12796.2 EKG20798.1 - 2.4e-18 66.2 0.7 2.6e-11 43.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKG20798.1 - 6.4e-15 54.1 0.3 4.3e-06 26.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EKG20798.1 - 3e-13 49.8 0.3 1e-06 29.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG20798.1 - 7.4e-13 48.2 1.1 1.7e-06 28.0 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG20798.1 - 1.3e-10 40.4 0.4 0.014 15.5 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat HH_signal PF01085.13 EKG20798.1 - 0.012 15.2 0.1 0.033 13.7 0.0 1.7 2 0 0 2 2 2 0 Hedgehog amino-terminal signalling domain Cupin_4 PF08007.7 EKG20798.1 - 0.025 13.8 3.7 0.057 12.6 2.5 1.7 1 0 0 1 1 1 0 Cupin superfamily protein LMWPc PF01451.16 EKG20798.1 - 0.097 12.9 1.2 0.25 11.6 0.8 1.7 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase Mu-like_Pro PF10123.4 EKG20798.1 - 4.1 6.7 15.7 18 4.6 10.9 2.1 1 1 0 1 1 1 0 Mu-like prophage I protein APG6 PF04111.7 EKG20798.1 - 8.5 5.3 14.4 11 4.9 9.6 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4523 PF15023.1 EKG20801.1 - 0.029 13.8 0.1 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Pcc1 PF09341.5 EKG20803.1 - 3.4e-24 84.6 0.0 4.3e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF2277 PF10041.4 EKG20805.1 - 0.041 13.8 0.6 1.8 8.6 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) Nop52 PF05997.7 EKG20805.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleolar protein,Nop52 Anp1 PF03452.9 EKG20806.1 - 3.8e-110 367.2 0.0 4.4e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EKG20806.1 - 0.0076 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 CENP-U PF13097.1 EKG20806.1 - 0.22 11.4 3.4 0.34 10.8 2.3 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Glyco_transf_15 PF01793.11 EKG20806.1 - 0.96 8.3 4.5 0.62 8.9 0.1 2.0 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L18p PF00861.17 EKG20809.1 - 1e-43 148.3 0.2 1e-43 148.3 0.2 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EKG20809.1 - 2.5e-32 111.3 9.7 2.5e-32 111.3 6.7 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EKG20809.1 - 0.052 13.5 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 Threonine synthase N terminus DUF3135 PF11333.3 EKG20810.1 - 0.012 15.7 0.3 0.041 14.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) DUF2829 PF11195.3 EKG20810.1 - 0.09 13.2 0.1 0.42 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) NUDIX_4 PF14815.1 EKG20812.1 - 0.13 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain DUF605 PF04652.11 EKG20813.1 - 0.11 11.8 11.4 0.11 11.8 7.9 1.1 1 0 0 1 1 1 0 Vta1 like Neisseria_TspB PF05616.8 EKG20813.1 - 0.45 8.8 6.8 0.54 8.5 4.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ECH PF00378.15 EKG20814.1 - 3.8e-28 98.2 0.0 4.9e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family KTI12 PF08433.5 EKG20815.1 - 1.1e-87 293.7 0.0 1.2e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EKG20815.1 - 3.7e-05 23.6 0.1 6.7e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG20815.1 - 0.028 15.2 0.0 0.056 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EKG20815.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EKG20815.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.7 EKG20815.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FA PF08736.6 EKG20816.1 - 0.011 15.5 0.5 1.9 8.3 0.2 2.6 2 0 0 2 2 2 0 FERM adjacent (FA) DUF3431 PF11913.3 EKG20817.1 - 5.4e-79 264.7 0.2 6.6e-79 264.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Syntaxin PF00804.20 EKG20819.1 - 2.2e-07 30.9 1.9 2.2e-07 30.9 1.3 2.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EKG20819.1 - 2.6e-07 30.2 5.8 2.6e-07 30.2 4.0 2.3 2 0 0 2 2 2 1 SNARE domain DUF2721 PF11026.3 EKG20819.1 - 0.012 15.2 0.8 0.24 11.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Spectrin PF00435.16 EKG20819.1 - 0.032 14.5 7.8 3.3 8.0 0.1 3.3 2 1 0 2 2 2 0 Spectrin repeat Sigma_reg_N PF13800.1 EKG20819.1 - 0.12 12.3 1.4 0.37 10.8 0.2 2.2 1 1 1 2 2 2 0 Sigma factor regulator N-terminal YjgP_YjgQ PF03739.9 EKG20819.1 - 0.13 11.0 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2077 PF09850.4 EKG20819.1 - 0.35 10.2 3.5 0.3 10.4 0.5 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF4094 PF13334.1 EKG20819.1 - 0.4 11.0 0.1 0.4 11.0 0.0 3.8 3 2 1 4 4 4 0 Domain of unknown function (DUF4094) Syntaxin_2 PF14523.1 EKG20819.1 - 0.41 10.7 12.8 0.098 12.6 4.8 2.2 2 0 0 2 2 2 0 Syntaxin-like protein Herpes_US9 PF06072.6 EKG20819.1 - 0.44 10.4 1.7 0.92 9.3 0.4 2.0 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 SlyX PF04102.7 EKG20819.1 - 0.64 10.4 11.7 0.09 13.1 3.0 2.9 2 1 0 2 2 2 0 SlyX Mod_r PF07200.8 EKG20819.1 - 0.67 9.8 12.2 0.69 9.8 0.9 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PilJ PF13675.1 EKG20819.1 - 1.5 9.1 7.5 3 8.2 0.3 2.9 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF972 PF06156.8 EKG20819.1 - 3.1 8.1 9.4 4 7.8 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF2203 PF09969.4 EKG20819.1 - 3.7 7.7 8.8 1.9 8.7 0.9 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) WD40 PF00400.27 EKG20820.1 - 5.5e-53 175.0 20.4 7.2e-07 28.8 0.1 12.7 13 0 0 13 13 13 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 EKG20820.1 - 0.0058 16.3 0.3 17 5.2 0.0 4.3 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 EKG20820.1 - 0.084 12.6 2.1 0.31 10.7 1.4 2.1 1 0 0 1 1 1 0 FG-GAP repeat Urm1 PF09138.6 EKG20821.1 - 8.7e-35 118.7 0.0 1e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EKG20821.1 - 0.0027 18.1 0.0 0.0032 17.8 0.0 1.2 1 0 0 1 1 1 1 ThiS family p450 PF00067.17 EKG20826.1 - 8.3e-49 166.3 0.0 1e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EKG20827.1 - 3.3e-12 46.0 0.5 6.7e-12 45.0 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG20827.1 - 6.7e-12 45.1 0.0 3.4e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like Nup188 PF10487.4 EKG20829.1 - 1.7e-46 158.6 0.0 4.8e-46 157.2 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 COPIIcoated_ERV PF07970.7 EKG20833.1 - 5.4e-35 121.0 0.1 8.8e-35 120.3 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EKG20833.1 - 1e-23 83.0 0.0 2.7e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NmrA PF05368.8 EKG20836.1 - 3.6e-07 29.6 0.0 5.6e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EKG20836.1 - 1.6e-05 24.9 0.3 3.6e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding CT47 PF15623.1 EKG20836.1 - 0.032 13.9 0.1 0.072 12.8 0.0 1.6 2 0 0 2 2 2 0 Cancer/testis gene family 47 KR PF08659.5 EKG20836.1 - 0.14 11.8 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 KR domain Shikimate_DH PF01488.15 EKG20836.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Homeobox PF00046.24 EKG20838.1 - 6.6e-13 48.0 6.0 6.6e-13 48.0 4.2 2.2 2 0 0 2 2 2 1 Homeobox domain Ribosomal_L7Ae PF01248.21 EKG20839.1 - 1.4e-25 88.5 0.1 1.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EKG20839.1 - 0.00086 19.1 0.1 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EKG20839.1 - 0.0067 16.1 0.0 0.0082 15.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.16 EKG20840.1 - 1.3e-31 108.2 33.1 3.8e-18 65.1 9.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EKG20840.1 - 0.2 11.2 4.0 0.081 12.4 0.8 1.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 EKG20840.1 - 2.9 7.5 8.6 1.2 8.7 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) GMC_oxred_N PF00732.14 EKG20843.1 - 5.7e-25 88.0 1.3 4e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG20843.1 - 1e-05 24.6 0.2 0.011 14.6 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG20843.1 - 0.0012 18.7 0.6 0.0029 17.5 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EKG20843.1 - 0.0013 18.7 0.2 0.02 14.8 0.0 2.6 3 0 0 3 3 3 1 TrkA-N domain Lycopene_cycl PF05834.7 EKG20843.1 - 0.0018 17.2 0.1 0.003 16.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EKG20843.1 - 0.0023 16.9 0.1 0.014 14.3 0.0 2.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EKG20843.1 - 0.011 14.8 0.3 0.019 14.0 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EKG20843.1 - 0.012 15.4 0.4 0.028 14.2 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_C PF05199.8 EKG20843.1 - 0.031 14.5 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.22 EKG20843.1 - 0.047 14.0 0.1 0.08 13.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG20843.1 - 0.061 11.7 0.1 0.1 11.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein COesterase PF00135.23 EKG20845.1 - 2.1e-47 162.0 0.0 2.7e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Glyco_hydro_76 PF03663.9 EKG20847.1 - 1.2e-89 301.3 14.9 1.4e-89 301.0 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Aldedh PF00171.17 EKG20848.1 - 4.2e-106 355.0 0.3 4.5e-106 354.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EKG20848.1 - 0.0017 17.6 0.0 0.019 14.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DFP PF04127.10 EKG20848.1 - 0.097 12.2 0.4 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein p450 PF00067.17 EKG20849.1 - 9.2e-11 40.9 0.0 1.2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EKG20850.1 - 3.2e-17 62.9 1.1 6.6e-17 61.9 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG20850.1 - 7.3e-07 29.0 0.2 1.2e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 KR domain FAD_binding_3 PF01494.14 EKG20851.1 - 1.3e-07 31.0 0.5 1.3e-06 27.7 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EKG20851.1 - 0.018 15.0 0.0 0.068 13.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG20851.1 - 0.047 12.5 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Sugar_tr PF00083.19 EKG20852.1 - 7.2e-31 107.2 9.2 8.1e-31 107.0 6.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter IL7 PF01415.11 EKG20854.1 - 0.0096 15.5 0.1 0.013 15.1 0.1 1.2 1 0 0 1 1 1 1 Interleukin 7/9 family p450 PF00067.17 EKG20856.1 - 4.8e-55 186.9 0.0 8.9e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Alpha-L-AF_C PF06964.7 EKG20856.1 - 2.4e-32 112.1 0.3 4.4e-32 111.2 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_transf_54 PF04666.8 EKG20856.1 - 0.03 13.0 0.2 0.048 12.3 0.1 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DUF1680 PF07944.7 EKG20858.1 - 6.8e-24 84.0 0.0 5e-21 74.5 0.0 2.7 2 1 1 3 3 3 2 Putative glycosyl hydrolase of unknown function (DUF1680) Leukocidin PF07968.7 EKG20859.1 - 0.015 14.9 1.2 0.028 14.0 0.1 1.8 2 0 0 2 2 2 0 Leukocidin/Hemolysin toxin family Ric8 PF10165.4 EKG20860.1 - 0.35 9.6 5.9 0.42 9.3 4.1 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Abhydrolase_5 PF12695.2 EKG20861.1 - 3.6e-12 46.2 4.1 5.5e-12 45.6 2.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EKG20861.1 - 5.9e-10 37.9 0.0 0.00024 19.5 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EKG20861.1 - 7.3e-08 32.5 12.5 3.6e-06 27.0 5.9 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Lipase_3 PF01764.20 EKG20861.1 - 0.039 13.5 1.7 0.091 12.3 1.2 1.6 1 0 0 1 1 1 0 Lipase (class 3) MmgE_PrpD PF03972.9 EKG20861.1 - 0.12 10.4 2.7 0.2 9.7 0.0 2.1 1 1 1 2 2 2 0 MmgE/PrpD family Tyr-DNA_phospho PF06087.7 EKG20864.1 - 9e-62 209.1 0.0 1.1e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EKG20864.1 - 4.5e-06 26.4 0.0 0.0036 17.0 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 EKG20864.1 - 0.00012 21.3 0.7 0.00037 19.8 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF605 PF04652.11 EKG20864.1 - 3.3 7.0 11.2 4.9 6.4 7.8 1.2 1 0 0 1 1 1 0 Vta1 like Arf PF00025.16 EKG20865.1 - 8.9e-74 246.4 0.3 1.1e-73 246.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKG20865.1 - 5.5e-14 51.7 0.0 6.7e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EKG20865.1 - 8.5e-13 48.0 0.0 9.7e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EKG20865.1 - 1.5e-12 46.9 1.7 4.5e-09 35.4 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EKG20865.1 - 4.6e-11 42.3 0.0 5.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EKG20865.1 - 6.7e-08 33.0 0.0 1e-07 32.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKG20865.1 - 0.00014 21.7 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG20865.1 - 0.0023 17.3 0.1 0.016 14.6 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EKG20865.1 - 0.015 14.4 0.2 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Glyco_transf_8 PF01501.15 EKG20866.1 - 3.1e-26 92.2 0.0 3.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 EKG20867.1 - 1.4e-57 191.3 0.1 7.6e-21 73.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1295 PF06966.7 EKG20868.1 - 6.8e-29 100.8 10.7 1.9e-23 83.0 4.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1295) p450 PF00067.17 EKG20869.1 - 9.1e-32 110.1 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Sigma54_CBD PF04963.8 EKG20869.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain p450 PF00067.17 EKG20870.1 - 5.7e-46 156.9 0.0 6.9e-45 153.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_92 PF07971.7 EKG20871.1 - 2.2e-138 462.0 0.0 2.9e-138 461.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 phiKZ_IP PF12699.2 EKG20873.1 - 0.017 14.0 0.1 0.056 12.3 0.0 1.8 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins CorA PF01544.13 EKG20873.1 - 0.033 13.2 0.9 0.11 11.5 0.1 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein GlutR_dimer PF00745.15 EKG20873.1 - 0.04 13.8 4.6 3.8 7.5 0.2 3.3 3 1 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF3582 PF12122.3 EKG20874.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3582) TPR_12 PF13424.1 EKG20876.1 - 5.3e-13 48.7 36.6 1.1e-06 28.5 0.3 10.6 7 4 2 10 10 10 4 Tetratricopeptide repeat AAA_22 PF13401.1 EKG20876.1 - 2.8e-07 30.7 1.4 3.2e-06 27.3 0.1 3.6 2 0 0 2 2 2 1 AAA domain TPR_19 PF14559.1 EKG20876.1 - 1e-06 28.9 25.5 0.2 12.0 0.1 9.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 EKG20876.1 - 6.4e-06 25.9 33.0 0.0075 16.1 0.1 9.2 10 1 2 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG20876.1 - 0.00041 19.9 25.3 6.7 6.7 0.0 9.9 10 0 0 10 10 10 3 Tetratricopeptide repeat NACHT PF05729.7 EKG20876.1 - 0.0018 17.9 0.0 0.0053 16.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.1 EKG20876.1 - 0.0037 17.6 9.7 12 6.5 0.2 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EKG20876.1 - 0.0038 17.7 21.3 26 5.8 0.0 10.0 9 2 2 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.1 EKG20876.1 - 0.0095 15.6 10.4 3.5 7.6 0.3 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG20876.1 - 0.074 13.0 19.0 1.6 8.8 0.3 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat VIT1 PF01988.14 EKG20877.1 - 0.04 13.4 0.6 0.055 12.9 0.4 1.1 1 0 0 1 1 1 0 VIT family Npa1 PF11707.3 EKG20880.1 - 8.2e-93 310.9 0.0 2.7e-92 309.3 0.0 1.9 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal HORMA PF02301.13 EKG20880.1 - 0.13 11.7 0.0 0.39 10.1 0.0 1.8 1 0 0 1 1 1 0 HORMA domain EF-hand_6 PF13405.1 EKG20881.1 - 2.3e-10 39.4 0.5 6.6e-05 22.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EKG20881.1 - 5.6e-07 28.4 0.6 1.5e-06 27.1 0.2 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EKG20881.1 - 1.9e-05 23.8 0.2 4.4e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EKG20881.1 - 2.1e-05 24.5 0.3 2.1e-05 24.5 0.2 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EKG20881.1 - 0.00027 20.5 0.3 0.00045 19.7 0.1 1.5 1 1 0 1 1 1 1 EF-hand domain pair DUF3383 PF11863.3 EKG20881.1 - 0.086 11.4 0.3 0.11 11.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) MFS_1 PF07690.11 EKG20882.1 - 2.6e-32 111.9 24.9 5.5e-32 110.8 17.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG20882.1 - 0.0014 17.2 14.0 0.0014 17.2 9.7 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1469 PF07332.6 EKG20882.1 - 0.0034 17.0 0.3 0.0034 17.0 0.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1469) BT1 PF03092.11 EKG20882.1 - 0.0059 15.3 1.9 0.011 14.4 1.3 1.5 1 1 0 1 1 1 1 BT1 family PTR2 PF00854.16 EKG20882.1 - 0.006 15.4 1.9 0.006 15.4 1.3 1.6 2 0 0 2 2 2 1 POT family DUF3397 PF11877.3 EKG20882.1 - 0.01 15.8 1.8 0.029 14.3 1.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3397) DUF998 PF06197.8 EKG20882.1 - 0.016 14.5 23.0 0.08 12.2 8.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF998) DUF1109 PF06532.6 EKG20882.1 - 0.037 13.4 7.4 0.019 14.4 3.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) DUF4149 PF13664.1 EKG20882.1 - 0.064 13.3 8.7 0.55 10.3 0.2 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF1129 PF06570.6 EKG20882.1 - 0.16 11.3 3.1 0.073 12.3 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4131 PF13567.1 EKG20882.1 - 0.57 9.5 17.5 0.049 13.0 6.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PepSY_TM_2 PF13703.1 EKG20882.1 - 6.9 6.9 14.0 1.6 8.9 4.1 3.6 2 1 1 3 3 3 0 PepSY-associated TM helix Tmemb_18A PF09771.4 EKG20882.1 - 8 6.4 6.8 0.45 10.4 0.1 2.1 2 1 0 2 2 2 0 Transmembrane protein 188 ABM PF03992.11 EKG20883.1 - 1.4e-10 41.0 0.6 1.8e-10 40.7 0.4 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ketoacyl-synt PF00109.21 EKG20883.1 - 0.01 15.2 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain DUF2076 PF09849.4 EKG20884.1 - 0.032 14.2 2.8 0.036 14.1 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Oxidored_FMN PF00724.15 EKG20886.1 - 3.2e-39 134.8 0.0 4.2e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M35 PF02102.10 EKG20889.1 - 6.7e-93 311.1 16.5 9e-93 310.7 11.4 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EKG20889.1 - 1.5e-10 41.7 1.0 4.4e-10 40.2 0.5 1.9 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase F5_F8_type_C PF00754.20 EKG20891.1 - 1.8e-15 56.9 5.3 2.2e-15 56.6 1.0 2.6 2 0 0 2 2 2 1 F5/8 type C domain Glyco_hydro_43 PF04616.9 EKG20891.1 - 1.5e-09 37.3 0.5 1.3e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 p450 PF00067.17 EKG20893.1 - 5.1e-40 137.3 0.0 6.5e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Na_H_Exchanger PF00999.16 EKG20894.1 - 7.2e-34 116.9 17.2 8.7e-34 116.6 11.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EKG20894.1 - 0.21 11.5 6.6 0.3 11.0 0.1 3.3 3 0 0 3 3 3 0 YrhC-like protein DUF3185 PF11381.3 EKG20894.1 - 9.1 6.1 10.1 13 5.6 2.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3185) RhoGEF PF00621.15 EKG20895.1 - 1.2e-06 28.5 0.0 3.5e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 RhoGEF domain Viral_env_E26 PF11050.3 EKG20895.1 - 0.046 12.9 0.6 0.1 11.7 0.4 1.5 1 0 0 1 1 1 0 Virus envelope protein E26 COesterase PF00135.23 EKG20897.1 - 4.1e-69 233.6 0.0 5.9e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Amidohydro_2 PF04909.9 EKG20897.1 - 6.8e-33 114.3 0.9 6.8e-33 114.3 0.6 1.8 2 0 0 2 2 2 1 Amidohydrolase Abhydrolase_3 PF07859.8 EKG20897.1 - 0.00037 20.1 0.2 0.0014 18.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.6 EKG20898.1 - 5.9e-28 97.7 0.5 1e-27 97.0 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 EKG20899.1 - 2.7e-78 263.5 24.5 3.2e-78 263.3 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG20899.1 - 6.5e-16 57.9 36.2 1.9e-09 36.7 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EKG20900.1 - 2.5e-14 53.5 2.9 3.6e-14 53.0 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG20900.1 - 6.5e-06 26.0 0.0 8.6e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_26 PF13659.1 EKG20900.1 - 0.029 14.4 2.7 0.04 13.9 1.7 1.4 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EKG20901.1 - 3.6e-28 98.2 26.0 5.1e-28 97.8 18.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily HET PF06985.6 EKG20903.1 - 8.9e-29 100.4 0.0 1.3e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) C1_3 PF07649.7 EKG20904.1 - 0.0016 18.4 8.4 0.0016 18.4 5.8 4.9 5 1 1 6 6 6 3 C1-like domain ZZ PF00569.12 EKG20904.1 - 0.0036 16.7 47.4 0.18 11.3 5.3 3.6 3 0 0 3 3 3 3 Zinc finger, ZZ type DUF2054 PF10218.4 EKG20904.1 - 0.0096 15.7 12.8 0.0096 15.7 8.9 3.1 1 1 2 3 3 3 1 Uncharacterized conserved protein (DUF2054) Sgf11 PF08209.6 EKG20904.1 - 0.14 11.5 0.1 0.14 11.5 0.1 4.9 4 2 1 5 5 5 0 Sgf11 (transcriptional regulation protein) Cript PF10235.4 EKG20904.1 - 0.41 11.0 37.4 0.35 11.2 7.6 3.3 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT FMN_dh PF01070.13 EKG20906.1 - 2.5e-105 352.2 0.1 2.9e-105 352.0 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EKG20906.1 - 0.00018 20.5 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EKG20906.1 - 0.0003 19.8 0.1 0.0025 16.7 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EKG20906.1 - 0.0046 16.1 0.9 0.037 13.1 0.1 2.1 1 1 1 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 EKG20906.1 - 0.017 14.2 0.0 0.37 9.8 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.12 EKG20906.1 - 0.072 12.2 0.0 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Peptidase_M19 PF01244.16 EKG20906.1 - 0.12 11.2 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) Fungal_trans PF04082.13 EKG20907.1 - 0.0019 17.1 0.1 0.0033 16.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG20907.1 - 0.036 13.9 0.7 0.064 13.1 0.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EKG20908.1 - 8.7e-61 205.2 0.0 1.1e-60 204.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zip PF02535.17 EKG20910.1 - 9.4e-47 159.5 1.5 1.2e-46 159.2 1.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter p450 PF00067.17 EKG20911.1 - 1e-57 195.7 0.0 1.3e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EKG20912.1 - 2.4e-24 86.4 13.5 4.2e-24 85.6 9.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG20912.1 - 9.3e-11 41.7 0.0 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG20912.1 - 0.0001 22.0 0.9 0.00085 19.1 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG20912.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Toxin_2 PF00451.14 EKG20913.1 - 0.12 12.5 37.1 0.29 11.2 10.1 3.1 2 2 0 2 2 2 0 Scorpion short toxin, BmKK2 MFS_1 PF07690.11 EKG20914.1 - 0.004 15.9 0.5 0.0055 15.4 0.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.19 EKG20914.1 - 0.0082 15.3 2.4 1.9 7.5 0.0 2.1 2 0 0 2 2 2 2 ABC-2 type transporter DUF1275 PF06912.6 EKG20914.1 - 0.49 9.5 4.5 0.078 12.1 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) HET PF06985.6 EKG20915.1 - 2.7e-26 92.3 0.0 5.1e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RALF PF05498.6 EKG20916.1 - 7.4e-24 84.3 8.1 1.3e-23 83.5 5.6 1.4 1 0 0 1 1 1 1 Rapid ALkalinization Factor (RALF) ADH_zinc_N PF00107.21 EKG20917.1 - 1.6e-12 47.0 0.0 3.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG20917.1 - 2e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EKG20917.1 - 0.046 13.2 0.2 0.072 12.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_FMN PF00724.15 EKG20918.1 - 1.8e-71 240.9 0.0 2.3e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Asp_Glu_race PF01177.17 EKG20918.1 - 0.0012 18.7 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase 2OG-FeII_Oxy_2 PF13532.1 EKG20919.1 - 2.6e-25 89.4 0.0 5.5e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TEBP_beta PF07404.6 EKG20921.1 - 0.91 8.5 2.8 1.1 8.3 2.0 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) adh_short PF00106.20 EKG20922.1 - 0.0052 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GalP_UDP_transf PF01087.17 EKG20923.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Ank_2 PF12796.2 EKG20925.1 - 4.3e-35 119.9 1.5 1e-06 28.9 0.0 7.2 1 1 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EKG20925.1 - 1e-31 108.7 5.1 0.0015 18.9 0.0 11.8 6 3 4 11 11 11 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG20925.1 - 1.2e-28 98.5 5.6 0.00016 21.7 0.1 9.9 6 3 5 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG20925.1 - 3.4e-15 54.6 4.9 0.024 14.8 0.0 11.2 13 0 0 13 13 13 3 Ankyrin repeat Ank PF00023.25 EKG20925.1 - 1.6e-14 52.8 19.9 0.25 11.2 0.0 11.8 13 1 0 13 13 13 6 Ankyrin repeat NACHT PF05729.7 EKG20925.1 - 0.00016 21.3 0.3 0.0062 16.2 0.0 2.5 1 1 1 2 2 2 1 NACHT domain UL11 PF11094.3 EKG20926.1 - 0.15 11.8 0.4 0.35 10.7 0.3 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein CHZ PF09649.5 EKG20926.1 - 2.1 7.6 4.0 1.4 8.1 0.2 2.2 2 0 0 2 2 2 0 Histone chaperone domain CHZ Cu_amine_oxid PF01179.15 EKG20927.1 - 4.4e-161 536.2 0.0 5.4e-161 535.9 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EKG20927.1 - 4e-08 33.2 0.0 7.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EKG20927.1 - 3.4e-06 27.0 0.0 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain GSHPx PF00255.14 EKG20929.1 - 1.7e-38 130.3 0.0 2.1e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase DUF4174 PF13778.1 EKG20929.1 - 0.00022 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) AhpC-TSA PF00578.16 EKG20929.1 - 0.0036 16.9 0.0 0.0075 15.9 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKG20929.1 - 0.0081 15.7 0.1 0.012 15.1 0.1 1.6 1 1 0 1 1 1 1 Redoxin zf-C2H2 PF00096.21 EKG20930.1 - 0.08 13.3 1.9 1.3 9.5 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG20930.1 - 3.2 8.2 12.3 1.5 9.3 0.1 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger YqzE PF14038.1 EKG20931.1 - 0.58 9.9 5.6 1.3 8.8 3.9 1.5 1 0 0 1 1 1 0 YqzE-like protein Use1 PF09753.4 EKG20932.1 - 2.2e-05 24.0 2.0 3.5e-05 23.3 1.4 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 Synaptobrevin PF00957.16 EKG20932.1 - 0.09 12.3 0.0 0.09 12.3 0.0 2.2 3 0 0 3 3 3 0 Synaptobrevin bZIP_1 PF00170.16 EKG20932.1 - 0.47 10.4 5.8 0.1 12.5 1.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor Coatomer_E PF04733.9 EKG20933.1 - 2.4e-61 207.4 6.1 2.7e-61 207.3 4.2 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_1 PF00515.23 EKG20933.1 - 6.1e-06 25.6 3.7 0.0002 20.7 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG20933.1 - 1.2e-05 24.7 2.7 0.039 13.7 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG20933.1 - 7.4e-05 22.3 0.0 7.4e-05 22.3 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG20933.1 - 8.6e-05 23.1 1.6 8.6e-05 23.1 1.1 4.8 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EKG20933.1 - 0.00016 21.2 0.0 0.00016 21.2 0.0 4.1 4 1 1 5 5 5 1 TPR repeat TPR_14 PF13428.1 EKG20933.1 - 0.0012 19.3 0.1 0.0012 19.3 0.1 6.1 3 2 4 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG20933.1 - 0.0029 17.8 1.2 0.0029 17.8 0.9 4.5 2 1 1 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EKG20933.1 - 0.003 17.6 8.5 0.76 9.9 0.1 3.4 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EKG20933.1 - 0.0036 17.2 16.9 0.006 16.4 0.3 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG20933.1 - 0.012 15.3 0.9 0.97 9.3 0.0 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EKG20933.1 - 0.13 12.7 0.2 0.13 12.7 0.2 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EKG20933.1 - 0.2 12.2 0.0 0.2 12.2 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EKG20933.1 - 6.8 6.7 10.4 6.2 6.9 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat Sulfotransfer_3 PF13469.1 EKG20934.1 - 2.1e-05 25.4 1.5 3.2e-05 24.8 1.0 1.4 1 1 0 1 1 1 1 Sulfotransferase family FAD_binding_3 PF01494.14 EKG20935.1 - 1.3e-18 67.2 0.5 1.6e-18 66.8 0.4 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG20935.1 - 2e-07 30.2 2.9 0.0061 15.4 0.2 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EKG20935.1 - 2e-07 30.4 0.3 9.1e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EKG20935.1 - 2.1e-07 30.2 0.6 0.0059 15.5 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EKG20935.1 - 0.0016 18.5 0.5 0.021 14.8 0.4 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG20935.1 - 0.0027 18.0 0.4 0.05 14.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EKG20935.1 - 0.0029 16.3 0.3 1.3 7.6 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 EKG20935.1 - 0.0036 17.2 0.0 0.006 16.4 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG20935.1 - 0.0082 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG20935.1 - 0.013 14.3 0.6 0.044 12.6 0.0 1.8 1 1 1 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 EKG20935.1 - 0.016 14.9 1.5 1 9.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EKG20935.1 - 0.028 13.5 0.1 0.036 13.1 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EKG20935.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EKG20935.1 - 0.095 11.1 0.1 3.8 5.8 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EKG20935.1 - 0.13 11.0 0.7 0.38 9.5 0.5 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A LigB PF02900.13 EKG20936.1 - 1.1e-36 126.2 0.0 1.4e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase LytR_C PF13399.1 EKG20936.1 - 0.043 14.1 0.0 0.37 11.1 0.0 2.0 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator NmrA PF05368.8 EKG20937.1 - 0.00028 20.1 0.0 0.00039 19.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HPP PF04982.8 EKG20938.1 - 1.7e-40 137.6 5.6 1.7e-40 137.6 3.9 1.6 2 0 0 2 2 2 1 HPP family EmrE PF13536.1 EKG20938.1 - 0.0032 17.6 3.3 0.0032 17.6 2.3 1.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF4231 PF14015.1 EKG20938.1 - 8 6.4 9.3 0.8 9.7 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) TauD PF02668.11 EKG20939.1 - 5.4e-32 111.4 0.1 7.4e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_30 PF13604.1 EKG20939.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EKG20940.1 - 3.5e-13 49.0 33.0 3.5e-13 49.0 22.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EKG20940.1 - 2.2e-09 37.0 4.6 6.4e-09 35.4 3.2 1.8 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 ABC2_membrane_2 PF12679.2 EKG20941.1 - 1.2 7.9 6.0 1.7 7.4 4.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Raptor_N PF14538.1 EKG20942.1 - 0.0051 16.6 0.6 0.12 12.2 0.2 2.9 2 1 0 2 2 2 1 Raptor N-terminal CASPase like domain GNVR PF13807.1 EKG20942.1 - 0.13 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase ADH_N PF08240.7 EKG20943.1 - 9.9e-19 67.1 0.1 2.6e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG20943.1 - 3.1e-08 33.2 1.5 1.9e-07 30.6 1.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EKG20943.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein DUF326 PF03860.11 EKG20944.1 - 3.9 7.4 6.0 0.71 9.7 1.7 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) GAF_2 PF13185.1 EKG20945.1 - 1.1e-08 35.7 0.0 1.1e-08 35.6 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 EKG20945.1 - 4.8e-05 23.5 0.1 5.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EKG20945.1 - 0.003 17.6 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain DUF837 PF05769.6 EKG20947.1 - 0.0014 18.2 4.6 0.0014 18.2 3.2 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF837) Spc7 PF08317.6 EKG20947.1 - 0.007 15.0 4.3 0.007 15.0 3.0 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein Filament PF00038.16 EKG20947.1 - 0.03 13.8 17.2 0.018 14.4 8.0 2.6 1 1 0 2 2 2 0 Intermediate filament protein RasGAP_C PF03836.10 EKG20947.1 - 0.032 13.9 0.9 0.032 13.9 0.6 1.9 1 1 1 2 2 2 0 RasGAP C-terminus Cmyb_C PF09316.5 EKG20947.1 - 0.069 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 C-myb, C-terminal DUF3837 PF12939.2 EKG20947.1 - 0.071 13.1 0.1 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) CENP-F_leu_zip PF10473.4 EKG20947.1 - 0.084 12.7 0.1 0.084 12.7 0.1 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31 PF05529.7 EKG20947.1 - 0.1 12.0 1.5 0.24 10.8 1.0 1.6 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like bZIP_1 PF00170.16 EKG20947.1 - 0.13 12.2 0.4 0.13 12.2 0.3 3.4 4 1 0 4 4 4 0 bZIP transcription factor DFF40 PF09230.5 EKG20947.1 - 0.17 11.1 4.0 0.11 11.8 0.3 2.1 1 1 1 2 2 2 0 DNA fragmentation factor 40 kDa Med9 PF07544.8 EKG20947.1 - 0.4 10.4 9.7 4.2 7.1 0.4 4.2 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 EKG20947.1 - 1.7 8.9 8.8 2.7 8.3 0.6 2.5 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EKG20947.1 - 3.2 7.8 10.8 2.2 8.4 5.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family NYD-SP28_assoc PF14775.1 EKG20947.1 - 8.5 6.1 11.2 0.37 10.5 0.3 3.5 4 0 0 4 4 4 0 Sperm tail C-terminal domain ADIP PF11559.3 EKG20947.1 - 9.3 6.1 19.9 0.12 12.2 6.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.4 EKG20947.1 - 10 6.2 10.7 14 5.7 0.9 3.2 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Tom22 PF04281.8 EKG20948.1 - 5e-45 152.4 0.4 5.7e-45 152.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Porin_3 PF01459.17 EKG20950.1 - 4.9e-81 272.0 0.0 6.2e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 EKG20951.1 - 1.3e-59 200.9 0.0 1.9e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EKG20951.1 - 1.8e-23 83.4 1.7 3e-23 82.6 1.2 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EKG20951.1 - 0.0023 18.7 0.0 0.0069 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG20951.1 - 0.0049 16.7 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EKG20951.1 - 0.093 11.9 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 p450 PF00067.17 EKG20952.1 - 5.3e-11 41.6 0.0 5.8e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1325 PF07039.6 EKG20953.1 - 5.8e-25 87.4 0.0 8.9e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4588 PF15251.1 EKG20953.1 - 0.011 15.7 1.3 0.018 14.9 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) PMI_typeI PF01238.16 EKG20954.1 - 3.7e-146 486.8 0.0 4.3e-146 486.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Amidoligase_2 PF12224.3 EKG20955.1 - 5.3e-20 72.1 0.0 5e-19 68.9 0.0 2.2 1 1 0 1 1 1 1 Putative amidoligase enzyme adh_short_C2 PF13561.1 EKG20956.1 - 1.8e-11 44.3 0.0 3.1e-11 43.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase P5CR_dimer PF14748.1 EKG20957.1 - 0.0025 17.8 0.8 0.0045 16.9 0.5 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Phage_Gp23 PF10669.4 EKG20957.1 - 0.047 13.8 1.2 0.058 13.5 0.9 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DNA_pol_viral_N PF00242.12 EKG20957.1 - 0.16 10.9 2.4 0.18 10.8 1.7 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4557 PF15101.1 EKG20957.1 - 2 8.2 4.9 2.7 7.7 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Acetyltransf_1 PF00583.19 EKG20959.1 - 1.4e-06 28.2 0.0 2.1e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EKG20959.1 - 0.0001 22.4 0.2 0.00063 19.8 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG20959.1 - 0.0025 17.9 0.0 0.0038 17.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG20959.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein AA_permease_2 PF13520.1 EKG20960.1 - 7.6e-51 172.9 50.5 9e-51 172.7 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG20960.1 - 6.6e-29 100.5 44.4 8.4e-29 100.2 30.8 1.0 1 0 0 1 1 1 1 Amino acid permease Clr2 PF10383.4 EKG20961.1 - 0.029 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 DUF605 PF04652.11 EKG20961.1 - 0.19 11.1 17.9 0.42 9.9 12.4 1.5 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 EKG20961.1 - 0.26 9.6 6.5 0.35 9.2 4.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIA PF03153.8 EKG20961.1 - 0.79 9.5 6.2 1.2 8.9 4.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF2_N PF00176.18 EKG20962.1 - 3.9e-58 196.5 0.7 1.3e-57 194.8 0.5 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG20962.1 - 1.4e-08 34.5 0.2 5.5e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_14 PF13173.1 EKG20962.1 - 0.016 15.1 0.2 1.2 9.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain YqzE PF14038.1 EKG20962.1 - 0.074 12.8 3.3 1.1 9.1 0.2 3.0 2 0 0 2 2 2 0 YqzE-like protein PHD PF00628.24 EKG20962.1 - 2 8.1 27.2 0.017 14.7 7.9 3.0 3 0 0 3 3 3 0 PHD-finger Pyr_redox_3 PF13738.1 EKG20964.1 - 4.7e-07 30.0 0.0 6.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG20964.1 - 3e-06 27.1 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG20964.1 - 0.00014 20.9 0.0 0.00032 19.7 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG20964.1 - 0.00038 20.2 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKG20964.1 - 0.00092 18.3 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EKG20964.1 - 0.0035 16.4 0.0 0.0044 16.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EKG20964.1 - 0.0071 16.7 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG20964.1 - 0.011 14.8 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG20964.1 - 0.029 13.2 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EKG20964.1 - 0.034 12.6 0.1 0.042 12.3 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EKG20964.1 - 0.074 12.9 0.0 0.094 12.5 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG20964.1 - 0.086 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.19 EKG20965.1 - 5.2e-05 22.3 0.2 9.7e-05 21.4 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase MFS_1 PF07690.11 EKG20967.1 - 3.3e-20 72.0 28.6 4e-20 71.8 17.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EKG20967.1 - 0.18 11.7 1.4 0.37 10.7 0.0 2.2 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Fungal_trans_2 PF11951.3 EKG20968.1 - 1.5e-09 36.9 1.2 8.7e-09 34.4 0.9 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG20968.1 - 5.9e-09 35.6 13.3 9.4e-09 35.0 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M20_dimer PF07687.9 EKG20969.1 - 1.1e-08 34.8 0.1 4.7e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EKG20969.1 - 7.2e-07 28.8 1.7 1.2e-06 28.2 1.2 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 PAT1 PF09770.4 EKG20970.1 - 0.52 8.4 6.7 0.82 7.8 4.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EKG20970.1 - 0.8 9.5 7.0 1.4 8.7 4.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAP65_ASE1 PF03999.7 EKG20970.1 - 0.93 8.0 5.6 1.3 7.5 3.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF605 PF04652.11 EKG20970.1 - 1.4 8.2 15.1 2.2 7.5 10.4 1.3 1 0 0 1 1 1 0 Vta1 like ABC_tran PF00005.22 EKG20974.1 - 2.2e-20 73.3 0.0 1.5e-08 35.0 0.0 3.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EKG20974.1 - 8.8e-09 35.7 0.1 0.0058 16.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EKG20974.1 - 5.3e-07 29.4 0.0 0.00066 19.5 0.1 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EKG20974.1 - 0.029 14.6 0.5 0.06 13.6 0.4 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EKG20974.1 - 0.035 13.6 0.2 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG20974.1 - 0.043 13.9 0.1 0.35 11.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain Adhesin_P1 PF03257.8 EKG20974.1 - 0.16 12.2 2.8 15 5.9 0.0 3.1 2 1 0 2 2 2 0 Mycoplasma adhesin P1 AAA_13 PF13166.1 EKG20974.1 - 0.17 10.3 0.0 0.25 9.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Glyco_hydro_15 PF00723.16 EKG20976.1 - 1.2e-65 221.8 0.0 1.5e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DUF608 PF04685.8 EKG20976.1 - 0.0054 15.5 0.1 0.0075 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Bac_rhamnosid PF05592.6 EKG20976.1 - 0.1 10.7 0.1 0.17 10.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase OPT PF03169.10 EKG20978.1 - 2.7e-35 121.9 1.8 3.2e-35 121.6 1.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 EKG20979.1 - 1.3e-65 222.0 9.1 1.4e-65 221.9 6.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BiPBP_C PF06832.7 EKG20983.1 - 0.024 14.5 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 Penicillin-Binding Protein C-terminus Family OCD_Mu_crystall PF02423.10 EKG20985.1 - 1.5e-11 43.6 0.6 2.1e-10 39.8 0.4 2.0 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EKG20985.1 - 0.0072 16.4 0.0 0.042 13.9 0.0 2.1 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EKG20986.1 - 2.1e-12 46.6 0.1 2.6e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase TRI12 PF06609.8 EKG20987.1 - 3e-12 45.5 13.1 4.1e-12 45.0 9.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG20987.1 - 3.7e-12 45.6 32.8 8.7e-11 41.1 22.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_transf_8 PF01501.15 EKG20988.1 - 9.6e-12 44.7 0.0 1.8e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Acyltransferase PF01553.16 EKG20989.1 - 8.8e-18 64.0 0.0 1.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1754 PF08555.5 EKG20992.1 - 0.39 11.3 7.4 1 9.9 1.4 2.9 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Pantoate_ligase PF02569.10 EKG20993.1 - 5.2e-82 274.7 0.0 8.4e-82 274.0 0.0 1.3 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 EKG20994.1 - 1.8e-38 131.6 0.0 2.7e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG20994.1 - 1.3e-19 69.8 0.0 2.7e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EKG20994.1 - 5.4e-16 57.8 0.0 1.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EKG20994.1 - 0.0042 16.9 0.3 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Hydrolase PF00702.21 EKG20995.1 - 0.073 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EKG20996.1 - 2.8e-15 55.5 10.4 0.00054 19.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 EKG20997.1 - 1.2e-10 40.5 4.2 2.5e-09 36.2 2.9 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain AflR PF08493.5 EKG20997.1 - 0.017 14.1 7.9 0.029 13.4 5.5 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Uds1 PF15456.1 EKG20998.1 - 0.041 13.8 0.1 0.041 13.8 0.1 1.7 2 0 0 2 2 2 0 Up-regulated During Septation PPTA PF01239.17 EKG20999.1 - 4.8e-43 142.7 16.4 1.7e-08 33.4 0.0 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Spidroin_MaSp PF11260.3 EKG20999.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 PSCyt2 PF07583.6 EKG20999.1 - 0.14 11.6 6.9 0.05 13.0 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1549) WD40 PF00400.27 EKG21000.1 - 1.8e-11 43.4 7.3 7.7e-05 22.4 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Rft-1 PF04506.8 EKG21002.1 - 4e-49 167.4 7.9 3.1e-47 161.1 5.5 2.0 1 1 0 1 1 1 1 Rft protein FtsJ PF01728.14 EKG21003.1 - 8.8e-55 185.4 0.0 2.3e-54 184.1 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EKG21003.1 - 0.0021 17.7 0.0 0.0043 16.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG21003.1 - 0.0074 16.8 0.0 0.016 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain VLPT PF07122.6 EKG21003.1 - 0.019 14.5 0.1 0.042 13.5 0.1 1.6 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Arginase PF00491.16 EKG21004.1 - 2.8e-72 243.3 0.1 3.1e-72 243.1 0.1 1.0 1 0 0 1 1 1 1 Arginase family Abhydrolase_6 PF12697.2 EKG21005.1 - 7.3e-22 78.3 2.9 1e-21 77.8 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG21005.1 - 4.3e-11 42.7 1.0 1.5e-10 40.9 0.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG21005.1 - 1.3e-07 31.4 0.3 3.2e-07 30.1 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EKG21005.1 - 0.047 13.1 0.1 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase BAAT_C PF08840.6 EKG21005.1 - 0.19 11.4 0.3 0.62 9.7 0.0 1.8 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chorismate_bind PF00425.13 EKG21006.1 - 3.7e-70 236.1 0.0 7.3e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 EKG21006.1 - 1.5e-24 86.5 0.0 6.7e-24 84.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EKG21006.1 - 1.1e-12 48.0 0.0 2.5e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EKG21006.1 - 1.2e-05 24.8 0.1 3.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 zf-C2H2_4 PF13894.1 EKG21007.1 - 2.3e-06 27.5 12.0 0.00057 20.0 2.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG21007.1 - 0.0025 18.0 17.4 0.042 14.1 4.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type EHN PF06441.7 EKG21008.1 - 2.3e-33 114.4 0.4 6.6e-33 112.9 0.3 1.8 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Git3 PF11710.3 EKG21008.1 - 1.8e-19 70.1 6.8 3.6e-19 69.1 4.7 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EKG21008.1 - 1.2e-09 37.6 0.0 2.6e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Abhydrolase_6 PF12697.2 EKG21008.1 - 8.1e-08 32.4 0.1 3e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Dicty_CAR PF05462.6 EKG21008.1 - 1.5e-06 27.3 7.1 1.4e-05 24.1 4.6 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Abhydrolase_1 PF00561.15 EKG21008.1 - 0.00029 20.4 0.1 0.00061 19.4 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Git3_C PF11970.3 EKG21008.1 - 0.00054 19.6 0.0 0.0018 17.9 0.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Tub_2 PF04525.7 EKG21009.1 - 7.5e-17 61.3 0.1 1.1e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Tubby C 2 EF-hand_4 PF12763.2 EKG21011.1 - 1.5e-32 111.3 0.0 2e-12 46.7 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EKG21011.1 - 7.1e-09 35.6 0.0 3.3e-05 23.9 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EKG21011.1 - 4e-07 28.8 0.0 0.35 10.2 0.0 4.5 4 0 0 4 4 4 1 EF hand UBA PF00627.26 EKG21011.1 - 1e-06 28.4 0.1 3.8e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_8 PF13833.1 EKG21011.1 - 0.00079 18.9 0.0 0.62 9.7 0.0 3.6 3 1 0 3 3 3 1 EF-hand domain pair Macoilin PF09726.4 EKG21011.1 - 0.00097 17.5 13.2 0.00097 17.5 9.1 2.4 2 0 0 2 2 1 1 Transmembrane protein CENP-F_leu_zip PF10473.4 EKG21011.1 - 0.0024 17.7 8.9 0.0024 17.7 6.2 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF812 PF05667.6 EKG21011.1 - 0.0099 14.4 20.5 0.021 13.3 14.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) WEMBL PF05701.6 EKG21011.1 - 0.024 13.1 25.6 0.034 12.6 17.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light IncA PF04156.9 EKG21011.1 - 0.026 14.1 32.2 0.028 14.0 14.2 2.2 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 EKG21011.1 - 0.035 11.4 23.9 0.048 10.9 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EKG21011.1 - 0.037 13.2 9.8 0.02 14.0 1.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3450 PF11932.3 EKG21011.1 - 0.066 12.4 28.2 0.1 11.8 10.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.4 EKG21011.1 - 0.31 9.9 33.8 0.028 13.3 8.3 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MAD PF05557.8 EKG21011.1 - 0.41 8.6 27.5 0.62 8.0 19.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein BicD PF09730.4 EKG21011.1 - 0.52 8.5 28.7 4.2 5.6 20.0 1.7 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D EzrA PF06160.7 EKG21011.1 - 0.57 8.3 21.3 0.94 7.5 14.7 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.1 EKG21011.1 - 0.67 9.1 30.3 0.47 9.6 10.8 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EKG21011.1 - 1.1 7.5 19.5 2.2 6.6 13.5 1.4 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.7 EKG21011.1 - 4.7 7.0 10.5 3.1 7.6 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tnp_P_element PF12017.3 EKG21011.1 - 5.1 6.2 8.0 0.39 9.9 1.5 1.9 1 1 1 2 2 2 0 Transposase protein ADIP PF11559.3 EKG21011.1 - 7 6.5 33.4 2.6 7.9 10.6 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DJ-1_PfpI_N PF13587.1 EKG21012.1 - 0.078 12.5 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family Spore_YhcN_YlaJ PF09580.5 EKG21012.1 - 1.8 8.6 5.5 2.5 8.1 3.8 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) WW PF00397.21 EKG21013.1 - 6e-05 22.8 6.9 0.00013 21.7 4.8 1.6 1 0 0 1 1 1 1 WW domain F-box-like_2 PF13013.1 EKG21014.1 - 0.027 14.2 1.1 7.9 6.2 0.0 2.8 2 1 1 3 3 3 0 F-box-like domain DAO PF01266.19 EKG21015.1 - 1.5e-64 218.2 1.7 1.9e-64 217.8 1.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG21015.1 - 2e-05 24.5 1.5 0.0038 17.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EKG21015.1 - 0.00013 20.7 0.8 0.03 12.9 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EKG21015.1 - 0.00031 20.7 0.8 0.00077 19.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EKG21015.1 - 0.00082 18.3 0.2 0.016 14.1 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EKG21015.1 - 0.0015 17.4 1.6 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EKG21015.1 - 0.014 15.7 0.0 0.52 10.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EKG21015.1 - 0.062 12.4 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase cwf21 PF08312.7 EKG21016.1 - 3.7e-19 68.2 9.3 3.7e-19 68.2 6.5 2.7 4 0 0 4 4 4 1 cwf21 domain DUF3353 PF11833.3 EKG21016.1 - 0.13 11.7 2.3 0.2 11.0 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) CPSase_L_D3 PF02787.14 EKG21016.1 - 0.84 9.4 4.7 0.16 11.7 0.6 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain D123 PF07065.9 EKG21017.1 - 1.3e-94 316.6 0.0 2.5e-92 309.1 0.0 2.2 1 1 0 2 2 2 2 D123 Nop53 PF07767.6 EKG21017.1 - 0.02 13.9 2.4 0.029 13.3 1.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cupin_2 PF07883.6 EKG21018.1 - 1e-07 31.3 1.6 2.3e-07 30.2 1.1 1.6 1 0 0 1 1 1 1 Cupin domain FdtA PF05523.6 EKG21018.1 - 0.0006 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 WxcM-like, C-terminal MannoseP_isomer PF01050.13 EKG21018.1 - 0.038 13.6 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Amidohydro_4 PF13147.1 EKG21019.1 - 4.2e-12 46.6 2.9 5.7e-12 46.2 2.0 1.2 1 0 0 1 1 1 1 Amidohydrolase FMN_dh PF01070.13 EKG21020.1 - 5.4e-90 301.8 0.1 3.7e-88 295.7 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Amidohydro_5 PF13594.1 EKG21020.1 - 0.00038 20.2 0.0 0.00075 19.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase IMPDH PF00478.20 EKG21020.1 - 0.087 11.6 0.0 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Cohesin_load PF10345.4 EKG21021.1 - 6.3e-124 414.4 10.5 7.1e-124 414.2 7.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_7 PF13176.1 EKG21021.1 - 0.089 12.6 0.1 2.2 8.3 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EKG21022.1 - 1.7e-06 28.0 0.0 1.6e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG21022.1 - 1.3e-05 24.9 0.0 2.9e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG21022.1 - 2.2e-05 24.1 0.0 0.0021 17.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Cutinase PF01083.17 EKG21022.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase UPF0220 PF05255.6 EKG21024.1 - 2.9e-69 231.5 4.6 3.3e-69 231.3 3.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Vps55 PF04133.9 EKG21025.1 - 1.5e-47 160.2 8.7 1.6e-47 160.1 6.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.21 EKG21026.1 - 4.9e-42 143.3 0.0 6.3e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Mak10 PF04112.8 EKG21027.1 - 2.9e-47 160.0 0.0 6.1e-47 158.9 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase MetRS-N PF09635.5 EKG21027.1 - 0.092 13.1 0.1 4.4 7.7 0.0 2.9 2 1 1 3 3 3 0 MetRS-N binding domain ATP-synt_Eps PF04627.8 EKG21028.1 - 1.1e-22 79.3 2.4 1.1e-22 79.3 1.7 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 EKG21029.1 - 4.4e-16 58.9 0.0 7.7e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EKG21029.1 - 4.8e-10 39.4 0.0 1.2e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 EKG21030.1 - 5.2e-41 140.8 0.0 4.9e-40 137.6 0.0 2.2 1 1 1 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EKG21030.1 - 1.1e-19 69.9 1.3 1.9e-13 50.0 0.3 4.6 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EKG21030.1 - 8e-09 34.9 1.4 4.4e-05 22.9 0.0 3.5 3 1 0 3 3 3 2 TFIIE alpha subunit TrmB PF01978.14 EKG21030.1 - 1.1e-06 28.1 3.5 1.3 8.7 0.0 6.1 6 0 0 6 6 6 1 Sugar-specific transcriptional regulator TrmB HTH_5 PF01022.15 EKG21030.1 - 0.051 13.2 1.6 11 5.7 0.1 3.6 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Velvet PF11754.3 EKG21032.1 - 1.9e-64 217.0 0.0 3.2e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Velvet factor TRAPPC10 PF12584.3 EKG21033.1 - 6e-19 67.9 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EKG21033.1 - 5.6e-05 22.7 0.2 9.8e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_19 PF14559.1 EKG21033.1 - 0.12 12.6 1.5 0.38 11.1 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RTA1 PF04479.8 EKG21034.1 - 6.2e-22 78.1 10.1 6.2e-22 78.1 7.0 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF308 PF03729.8 EKG21034.1 - 0.024 14.6 2.0 0.024 14.6 1.4 3.3 4 0 0 4 4 4 0 Short repeat of unknown function (DUF308) TPT PF03151.11 EKG21035.1 - 2.6e-39 134.3 0.4 2.6e-39 134.3 0.3 1.6 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EKG21035.1 - 9.9e-14 50.9 6.8 2.1e-13 49.8 4.7 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EKG21035.1 - 6.4e-07 29.4 29.4 2.6e-05 24.2 2.8 3.1 4 0 0 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EKG21035.1 - 0.0018 17.4 0.7 0.045 12.8 0.1 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF914 PF06027.7 EKG21035.1 - 0.0045 15.8 0.3 0.0045 15.8 0.2 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) Peptidase_S9 PF00326.16 EKG21036.1 - 1.4e-11 43.9 0.0 2.5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG21036.1 - 1.3e-09 37.9 0.0 2.7e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG21036.1 - 4.9e-06 26.1 0.0 0.0052 16.2 0.0 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase PUF PF00806.14 EKG21037.1 - 3.7e-38 126.8 3.0 1.4e-06 27.4 0.0 8.9 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat RHD3 PF05879.7 EKG21038.1 - 0 1033.1 0.0 0 1032.8 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EKG21038.1 - 6.2e-09 35.2 0.1 1e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EKG21038.1 - 1.5e-05 24.8 0.0 3.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EKG21038.1 - 0.00013 21.8 0.0 0.00035 20.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EKG21038.1 - 0.00024 21.0 0.2 0.0016 18.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EKG21038.1 - 0.0018 18.7 0.1 0.0042 17.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EKG21038.1 - 0.025 13.6 0.1 0.046 12.7 0.1 1.4 1 0 0 1 1 1 0 Septin NUC173 PF08161.7 EKG21038.1 - 0.066 12.5 0.1 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 NUC173 domain DUF3693 PF12472.3 EKG21038.1 - 0.078 12.5 1.1 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 Phage related protein GTP_EFTU PF00009.22 EKG21038.1 - 0.099 12.0 0.1 0.29 10.5 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Molybdopterin PF00384.17 EKG21039.1 - 7.1e-70 235.8 0.0 1.2e-67 228.5 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EKG21039.1 - 1.8e-19 69.2 0.1 5e-19 67.8 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EKG21039.1 - 4.7e-19 67.3 0.1 1.3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EKG21039.1 - 2.7e-14 53.0 0.0 7.6e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EKG21039.1 - 2.3e-08 33.6 0.4 2.3e-08 33.6 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EKG21039.1 - 0.00076 19.2 0.0 0.082 12.6 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EKG21039.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EKG21039.1 - 0.24 11.2 2.1 5.3 6.9 1.5 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster WD40 PF00400.27 EKG21040.1 - 2.5e-16 58.8 16.6 7.9e-05 22.3 0.8 6.9 8 0 0 8 8 8 4 WD domain, G-beta repeat eIF2A PF08662.6 EKG21040.1 - 0.0024 17.6 0.0 0.52 9.9 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Pex16 PF08610.5 EKG21041.1 - 1.3e-117 392.5 0.0 1.5e-117 392.3 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) HD PF01966.17 EKG21042.1 - 2.4e-06 27.5 3.6 2.4e-06 27.5 2.5 1.8 2 1 0 2 2 2 1 HD domain Ank PF00023.25 EKG21042.1 - 0.089 12.6 0.1 0.82 9.6 0.0 2.4 2 1 0 2 2 2 0 Ankyrin repeat DUF3090 PF11290.3 EKG21042.1 - 0.089 12.2 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) BC10 PF06726.7 EKG21043.1 - 4.1e-12 45.9 7.4 4.1e-12 45.9 5.1 1.6 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 Mito_carr PF00153.22 EKG21044.1 - 1.8e-36 123.7 0.0 6.4e-17 61.0 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein FDX-ACB PF03147.9 EKG21046.1 - 2.9e-24 85.0 0.0 4.8e-24 84.3 0.0 1.4 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.15 EKG21046.1 - 0.059 12.5 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Aldedh PF00171.17 EKG21047.1 - 3.5e-149 497.0 0.0 4.3e-149 496.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EKG21047.1 - 0.021 13.5 0.0 0.085 11.5 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) DUF1102 PF06510.6 EKG21048.1 - 0.0044 16.8 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1102) Phage_capsid PF05065.8 EKG21048.1 - 0.023 13.8 0.1 0.037 13.2 0.1 1.3 1 0 0 1 1 1 0 Phage capsid family CENP-F_leu_zip PF10473.4 EKG21049.1 - 1.9e-06 27.8 145.4 0.0018 18.1 7.1 9.2 3 2 4 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EKG21049.1 - 8e-06 23.8 127.9 4.7e-05 21.3 44.1 5.6 2 1 2 4 4 4 3 Myosin tail Tropomyosin_1 PF12718.2 EKG21049.1 - 2.6e-05 24.1 23.6 2.6e-05 24.1 16.3 7.9 2 1 5 7 7 4 1 Tropomyosin like AAA_13 PF13166.1 EKG21049.1 - 0.00024 19.7 16.9 0.00024 19.7 11.7 4.7 1 1 5 6 6 6 3 AAA domain AAA_27 PF13514.1 EKG21049.1 - 0.00061 17.6 50.3 0.00061 17.6 34.9 4.6 2 1 2 4 4 4 1 AAA domain IncA PF04156.9 EKG21049.1 - 0.0019 17.8 14.7 0.0019 17.8 10.2 9.2 3 2 5 8 8 7 4 IncA protein ERM PF00769.14 EKG21049.1 - 0.0052 16.3 17.4 0.0052 16.3 12.0 6.6 1 1 6 7 7 7 2 Ezrin/radixin/moesin family ATG16 PF08614.6 EKG21049.1 - 0.033 14.0 132.7 0.15 11.8 8.6 8.6 2 1 6 8 8 8 0 Autophagy protein 16 (ATG16) DUF869 PF05911.6 EKG21049.1 - 0.27 9.4 109.4 0.067 11.4 6.2 6.5 2 1 4 6 6 6 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EKG21049.1 - 0.32 10.1 45.3 0.089 11.9 3.1 6.3 2 1 5 7 7 7 0 Reovirus sigma C capsid protein APG6 PF04111.7 EKG21049.1 - 1.8 7.4 128.7 0.19 10.7 13.9 7.4 3 1 3 7 7 7 0 Autophagy protein Apg6 F-box-like PF12937.2 EKG21051.1 - 4.7e-06 26.2 1.5 0.025 14.3 0.3 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EKG21051.1 - 0.0017 17.9 0.7 0.051 13.2 0.2 2.4 2 0 0 2 2 2 1 F-box domain FtsZ_C PF12327.3 EKG21053.1 - 0.19 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DUF2910 PF11139.3 EKG21053.1 - 2.5 7.1 15.7 0.028 13.5 5.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Aconitase PF00330.15 EKG21054.1 - 4.2e-66 223.3 0.1 3.6e-41 141.1 0.0 2.6 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EKG21054.1 - 7.7e-27 93.9 0.0 1.5e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyoxalase PF00903.20 EKG21055.1 - 2e-12 47.1 0.1 2.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EKG21055.1 - 5.3e-06 26.9 0.0 8.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain SH3_9 PF14604.1 EKG21056.1 - 0.0046 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG21056.1 - 0.0047 16.2 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain HAUS2 PF15003.1 EKG21056.1 - 0.049 12.6 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Vps51 PF08700.6 EKG21057.1 - 1.1e-13 50.8 0.0 4.9e-13 48.7 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 DHH PF01368.15 EKG21059.1 - 3.4e-07 29.9 0.0 6.1e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 DHH family 2-Hacid_dh_C PF02826.14 EKG21060.1 - 2.3e-51 173.4 0.0 3.3e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EKG21060.1 - 5.5e-16 58.2 0.0 7.6e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EKG21060.1 - 0.00091 19.0 0.0 0.003 17.4 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase CM2 PF03021.9 EKG21060.1 - 0.13 11.8 0.1 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Influenza C virus M2 protein FH2 PF02181.18 EKG21061.1 - 1.9e-79 267.2 3.3 1.9e-79 267.2 2.3 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EKG21061.1 - 1.9e-67 226.2 0.0 4.1e-67 225.2 0.0 1.6 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EKG21061.1 - 3.8e-56 189.6 1.2 8.2e-55 185.2 0.4 2.6 1 1 1 2 2 2 1 Diaphanous FH3 Domain Med6 PF04934.9 EKG21063.1 - 1.8e-26 92.3 0.0 2.9e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF566 PF04484.7 EKG21063.1 - 3.7 6.9 14.5 5.4 6.4 3.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF566) MMtag PF10159.4 EKG21064.1 - 1.9e-15 56.6 0.2 1.9e-15 56.6 0.1 2.8 2 1 0 2 2 2 1 Kinase phosphorylation protein MIP-T3 PF10243.4 EKG21064.1 - 2.6 6.4 35.6 3.7 5.9 24.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Phosphodiest PF01663.17 EKG21065.1 - 7.8e-13 48.4 0.1 1.3e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EKG21065.1 - 0.0001 21.7 0.2 0.00018 20.9 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EKG21065.1 - 0.002 17.4 0.0 0.0033 16.6 0.0 1.5 1 0 0 1 1 1 1 Sulfatase RCR PF12273.3 EKG21066.1 - 0.0068 16.9 3.0 0.0079 16.7 1.1 1.8 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red PUF PF00806.14 EKG21067.1 - 1.4e-59 194.3 4.2 9.6e-08 31.1 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat YqzH PF14164.1 EKG21067.1 - 0.037 13.9 0.2 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 YqzH-like protein DUF260 PF03195.9 EKG21067.1 - 0.13 12.5 0.1 3.5 7.9 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function DUF260 DUF1640 PF07798.6 EKG21068.1 - 1.1e-13 51.6 3.8 1.4e-13 51.2 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) IncA PF04156.9 EKG21068.1 - 0.21 11.1 6.2 0.036 13.6 1.5 1.7 1 1 1 2 2 2 0 IncA protein FAD_binding_3 PF01494.14 EKG21069.1 - 5.7e-65 219.6 0.0 7.5e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EKG21069.1 - 7.8e-09 35.3 0.0 2.3e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EKG21069.1 - 5.5e-06 25.5 0.0 1.2e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EKG21069.1 - 0.00041 19.1 0.0 0.0006 18.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EKG21069.1 - 0.00054 20.0 0.0 0.00088 19.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EKG21069.1 - 0.00057 19.8 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EKG21069.1 - 0.0015 18.2 0.0 0.0042 16.8 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EKG21069.1 - 0.0034 16.5 0.0 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EKG21069.1 - 0.0041 16.2 0.4 2.3 7.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG21069.1 - 0.012 15.5 0.0 0.063 13.1 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG21069.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EKG21069.1 - 0.085 11.3 0.0 0.41 9.0 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EKG21069.1 - 0.14 12.6 0.0 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Acyl-CoA_dh_1 PF00441.19 EKG21070.1 - 9.4e-39 132.9 0.2 1.3e-38 132.3 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EKG21070.1 - 2.5e-16 58.9 0.4 5e-16 57.9 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EKG21070.1 - 3.2e-15 56.5 0.0 5.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EKG21070.1 - 5.2e-08 33.4 0.0 2.3e-07 31.3 0.0 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 EKG21070.1 - 0.0043 16.4 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Glyco_hydro_31 PF01055.21 EKG21071.1 - 1.4e-61 208.7 5.9 2.7e-61 207.7 4.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 RabGAP-TBC PF00566.13 EKG21073.1 - 1.1e-37 129.6 1.1 2.2e-37 128.6 0.8 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EKG21073.1 - 9.3e-12 44.6 0.0 1.5e-10 40.7 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) Tannase PF07519.6 EKG21074.1 - 4.1e-101 339.0 0.0 4.8e-101 338.8 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EKG21074.1 - 1.8e-05 24.7 0.0 9.5e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG21074.1 - 0.0016 17.7 0.0 0.22 10.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EKG21074.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 EKG21075.1 - 8.8e-20 71.1 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Cutinase Anillin PF08174.6 EKG21076.1 - 0.044 13.8 0.7 0.056 13.4 0.5 1.4 1 1 0 1 1 1 0 Cell division protein anillin Mak16 PF04874.9 EKG21077.1 - 2.8e-21 75.4 17.6 2.8e-21 75.4 12.2 3.0 2 1 0 2 2 2 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 EKG21077.1 - 8.2e-06 26.2 0.1 8.2e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Nop14 PF04147.7 EKG21077.1 - 0.0037 15.2 30.6 0.0054 14.7 21.2 1.2 1 0 0 1 1 1 1 Nop14-like family PYC_OADA PF02436.13 EKG21077.1 - 0.034 13.5 0.7 0.2 11.0 0.1 2.2 1 1 1 2 2 2 0 Conserved carboxylase domain BUD22 PF09073.5 EKG21077.1 - 0.1 11.6 32.6 0.18 10.8 22.6 1.4 1 1 0 1 1 1 0 BUD22 CENP-T PF15511.1 EKG21077.1 - 0.11 11.7 18.6 0.14 11.3 12.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Cwf_Cwc_15 PF04889.7 EKG21077.1 - 1.4 8.5 31.1 5.6 6.6 21.6 1.9 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.7 EKG21077.1 - 5.3 5.3 31.4 7.7 4.7 21.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EKG21077.1 - 8.3 4.3 23.9 0.43 8.5 12.6 1.6 2 0 0 2 2 2 0 CDC45-like protein Tubulin PF00091.20 EKG21078.1 - 6.5e-69 232.0 0.0 9.3e-69 231.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKG21078.1 - 8e-50 168.1 0.1 1.4e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EKG21078.1 - 0.0025 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EKG21078.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) WD40 PF00400.27 EKG21079.1 - 7.9e-23 79.4 3.3 1.6e-06 27.7 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF3639 PF12341.3 EKG21079.1 - 9.1e-10 38.3 1.0 9.1e-10 38.3 0.7 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EKG21079.1 - 0.0015 18.3 0.1 0.1 12.3 0.0 3.2 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EKG21079.1 - 0.0016 18.0 0.7 5.3 6.8 0.0 3.7 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EKG21079.1 - 0.015 15.5 1.7 1.5 9.1 0.0 3.7 3 0 0 3 3 3 0 PQQ-like domain IKI3 PF04762.7 EKG21079.1 - 0.019 12.8 0.1 0.054 11.3 0.0 1.6 1 1 0 1 1 1 0 IKI3 family LRR19-TM PF15176.1 EKG21079.1 - 0.024 14.3 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Nup160 PF11715.3 EKG21079.1 - 0.029 12.5 0.2 0.095 10.8 0.0 1.8 2 1 0 2 2 2 0 Nucleoporin Nup120/160 DNA_pol_alpha_N PF12254.3 EKG21079.1 - 0.17 11.7 2.5 0.4 10.5 1.7 1.5 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Hus1 PF04005.7 EKG21080.1 - 6.9e-103 343.5 0.0 7.8e-103 343.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein TrmE_N PF10396.4 EKG21081.1 - 3.6e-35 120.3 0.0 6.4e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EKG21081.1 - 4.2e-21 75.1 0.4 9.1e-21 74.0 0.3 1.6 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Vint PF14623.1 EKG21081.1 - 0.0053 16.2 0.0 0.0094 15.4 0.0 1.3 1 0 0 1 1 1 1 Hint-domain GTP_EFTU PF00009.22 EKG21081.1 - 0.17 11.2 0.0 0.71 9.2 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Atg8 PF02991.11 EKG21082.1 - 1.9e-51 172.3 0.3 2.2e-51 172.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EKG21082.1 - 3.3e-06 27.1 0.0 4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 HEAT_2 PF13646.1 EKG21083.1 - 2.1e-18 66.3 12.2 5.1e-05 23.4 0.0 9.0 8 1 2 10 10 10 5 HEAT repeats HEAT PF02985.17 EKG21083.1 - 7.1e-17 59.9 21.3 0.049 13.7 0.0 12.0 13 0 0 13 13 13 6 HEAT repeat HEAT_EZ PF13513.1 EKG21083.1 - 3.6e-07 30.4 13.2 0.019 15.4 0.0 9.1 8 1 2 10 10 10 3 HEAT-like repeat Adaptin_N PF01602.15 EKG21083.1 - 1.4e-05 23.6 6.7 0.018 13.3 0.1 5.0 3 1 1 4 4 4 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EKG21083.1 - 3.1e-05 24.2 0.0 0.51 10.7 0.0 4.1 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Transcrip_reg PF01709.15 EKG21084.1 - 6.2e-30 104.0 0.0 7.2e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator ECH PF00378.15 EKG21086.1 - 3e-27 95.2 0.0 3.8e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Aa_trans PF01490.13 EKG21088.1 - 1.1e-33 116.3 26.0 2.1e-33 115.4 18.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CN_hydrolase PF00795.17 EKG21089.1 - 3.2e-26 91.8 0.0 4.5e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Suc_Fer-like PF06999.7 EKG21090.1 - 0.00025 21.1 0.0 0.00027 21.0 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like adh_short_C2 PF13561.1 EKG21091.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG21091.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Glyco_hydro_61 PF03443.9 EKG21093.1 - 1.7e-77 260.1 0.1 2e-77 259.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DAO PF01266.19 EKG21094.1 - 5.2e-54 183.5 0.0 6.2e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG21094.1 - 7.1e-06 26.0 0.2 0.028 14.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EKG21094.1 - 2.2e-05 24.2 0.1 6.8e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 ThiF family FAD_binding_2 PF00890.19 EKG21094.1 - 3.6e-05 22.8 0.0 0.087 11.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EKG21094.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EKG21094.1 - 0.00068 18.6 0.0 0.61 8.8 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EKG21094.1 - 0.0031 17.2 0.1 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKG21094.1 - 0.004 16.2 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EKG21094.1 - 0.0049 16.9 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EKG21094.1 - 0.0092 15.6 0.0 0.033 13.8 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EKG21094.1 - 0.011 15.9 0.0 0.033 14.4 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EKG21094.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.9 EKG21094.1 - 0.014 14.0 0.1 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 EKG21094.1 - 0.057 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans_2 PF11951.3 EKG21095.1 - 3e-50 170.9 0.0 4e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EKG21097.1 - 5e-14 51.7 3.9 5.4e-14 51.6 2.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21097.1 - 0.034 12.7 2.2 0.029 12.9 0.9 1.3 2 0 0 2 2 2 0 Sugar (and other) transporter Glyco_hydro_63 PF03200.11 EKG21099.1 - 8.5e-235 781.3 0.1 7.8e-234 778.1 0.1 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EKG21099.1 - 7.4e-07 28.1 0.1 1.2e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Trehalase Surface_Ag_2 PF01617.12 EKG21099.1 - 0.0084 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Surface antigen DUF2635 PF10948.3 EKG21099.1 - 0.11 11.8 0.1 0.26 10.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Elong_Iki1 PF10483.4 EKG21100.1 - 1.8e-80 270.2 0.0 2.2e-80 270.0 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 ASXH PF13919.1 EKG21101.1 - 7.9e-30 103.4 0.0 1.5e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Asx homology domain Longin PF13774.1 EKG21102.1 - 5.2e-30 102.8 0.8 8.8e-30 102.0 0.2 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EKG21102.1 - 6.5e-16 57.7 0.0 1.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.19 EKG21102.1 - 0.011 15.5 1.6 0.21 11.2 0.2 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Chitin_synth_1N PF08407.6 EKG21102.1 - 0.074 12.7 0.3 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Chitin synthase N-terminal Seadorna_VP6 PF07407.6 EKG21102.1 - 0.13 11.0 0.4 0.19 10.4 0.3 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF1664 PF07889.7 EKG21102.1 - 0.13 12.0 1.2 0.35 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Glyco_trans_2_3 PF13632.1 EKG21103.1 - 3e-10 40.1 10.9 9.9e-10 38.4 7.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG21103.1 - 1.2e-09 38.3 0.1 2.6e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EKG21103.1 - 2.3e-06 27.0 0.4 7.4e-06 25.3 0.1 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 EKG21103.1 - 8.7e-06 24.3 5.1 0.00025 19.5 3.6 2.5 1 1 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.21 EKG21103.1 - 0.078 12.6 0.0 0.6 9.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 XPG_I PF00867.13 EKG21103.1 - 0.084 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 XPG I-region Transgly_assoc PF04226.8 EKG21103.1 - 0.54 10.3 4.8 3 7.9 0.4 3.0 3 0 0 3 3 3 0 Transglycosylase associated protein UbiA PF01040.13 EKG21105.1 - 0.015 14.5 9.4 0.02 14.1 6.5 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family FA_desaturase PF00487.19 EKG21105.1 - 1.2 8.5 4.9 1.6 8.0 3.4 1.2 1 0 0 1 1 1 0 Fatty acid desaturase RWD PF05773.17 EKG21108.1 - 3.3e-19 68.8 0.0 5.7e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EKG21108.1 - 3.9e-17 61.8 40.1 3.3e-13 49.2 1.4 3.9 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EKG21108.1 - 0.00014 21.6 9.5 0.00014 21.6 6.6 3.6 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EKG21108.1 - 0.00017 21.2 9.8 0.00017 21.2 6.8 3.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG21108.1 - 0.011 15.7 11.3 0.011 15.7 7.8 4.4 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) AA_permease_2 PF13520.1 EKG21110.1 - 4.8e-64 216.4 41.6 6.3e-64 216.0 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG21110.1 - 7e-30 103.7 26.4 7e-30 103.7 18.3 2.3 2 1 0 2 2 2 1 Amino acid permease tRNA-synt_1 PF00133.17 EKG21111.1 - 5.5e-56 189.8 0.0 2.3e-34 118.4 1.2 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EKG21111.1 - 1.5e-43 148.2 0.0 2.7e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EKG21111.1 - 1.7e-28 99.3 0.3 1.2e-20 73.5 0.0 4.8 3 2 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EKG21111.1 - 4.7e-13 49.1 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EKG21111.1 - 0.00082 18.2 0.3 0.0017 17.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EKG21111.1 - 0.031 13.4 0.0 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain STAT2_C PF12188.3 EKG21111.1 - 0.13 12.0 0.1 1.4 8.8 0.0 2.5 3 0 0 3 3 3 0 Signal transducer and activator of transcription 2 C terminal HA2 PF04408.18 EKG21112.1 - 4.7e-19 68.2 1.8 7.9e-19 67.5 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EKG21112.1 - 4.8e-15 55.1 0.0 2.3e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EKG21112.1 - 4.8e-11 42.4 0.0 1.3e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EKG21112.1 - 2e-10 40.4 0.0 6.8e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EKG21112.1 - 0.00077 19.3 3.5 0.38 10.5 0.0 3.7 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EKG21112.1 - 0.0034 17.5 1.0 0.026 14.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EKG21112.1 - 0.02 13.7 0.1 0.059 12.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 EKG21112.1 - 0.038 13.2 0.0 0.078 12.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Jiraiya PF15038.1 EKG21112.1 - 0.39 10.1 0.1 0.69 9.3 0.0 1.3 1 0 0 1 1 1 0 Jiraiya AAA_23 PF13476.1 EKG21112.1 - 4.4 7.5 20.0 3.4 7.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Fes1 PF08609.5 EKG21113.1 - 3.9e-32 110.5 3.5 3.9e-32 110.5 2.4 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EKG21113.1 - 6.7e-08 32.7 0.3 6.9e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 EKG21113.1 - 2e-06 27.4 0.4 0.094 12.5 0.1 2.7 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EKG21113.1 - 1.3e-05 25.5 0.8 0.001 19.5 0.1 2.9 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EKG21113.1 - 0.00024 20.9 0.0 0.022 14.7 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat RICTOR_V PF14668.1 EKG21113.1 - 0.069 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Actin PF00022.14 EKG21114.1 - 1.1e-158 527.8 0.0 1.2e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EKG21114.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) HSP70 PF00012.15 EKG21116.1 - 6.9e-05 20.9 0.0 8.6e-05 20.6 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKG21116.1 - 0.00067 18.3 0.0 0.0039 15.8 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein MFS_1 PF07690.11 EKG21118.1 - 3.1e-11 42.6 13.8 3.1e-11 42.6 9.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21118.1 - 0.00099 17.7 9.3 0.0012 17.5 6.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Form_Nir_trans PF01226.12 EKG21118.1 - 0.023 13.5 9.8 0.036 12.9 6.8 1.3 1 0 0 1 1 1 0 Formate/nitrite transporter DUF1282 PF06930.7 EKG21118.1 - 0.27 10.8 16.5 0.041 13.5 5.8 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) MFS_1 PF07690.11 EKG21119.1 - 7.2e-16 57.8 8.9 9.4e-16 57.4 6.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EKG21119.1 - 3.3e-06 25.8 3.1 4.2e-06 25.5 2.2 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like BT1 PF03092.11 EKG21119.1 - 0.019 13.6 0.1 0.019 13.6 0.1 1.2 1 0 0 1 1 1 0 BT1 family DUF3397 PF11877.3 EKG21119.1 - 0.038 13.9 4.1 0.073 13.0 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DUF443 PF04276.7 EKG21119.1 - 0.076 12.4 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) UPF0114 PF03350.11 EKG21119.1 - 0.09 12.7 0.7 0.14 12.1 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 DUF3784 PF12650.2 EKG21119.1 - 0.97 9.4 6.8 20 5.2 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) DUF1275 PF06912.6 EKG21119.1 - 1.1 8.4 7.3 0.032 13.4 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF485 PF04341.7 EKG21119.1 - 1.1 8.9 5.0 12 5.7 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF485 DUF3917 PF13055.1 EKG21119.1 - 2 8.6 5.5 54 4.1 3.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3917) FAD_binding_6 PF00970.19 EKG21120.1 - 1.5e-09 37.8 0.0 4.6e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EKG21120.1 - 2.4e-06 28.0 0.0 8e-06 26.3 0.0 1.9 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain DUF2314 PF10077.4 EKG21120.1 - 0.066 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2314) Suc_Fer-like PF06999.7 EKG21121.1 - 1e-44 153.3 0.0 1.3e-44 153.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MutS_V PF00488.16 EKG21122.1 - 7.9e-94 313.4 0.0 1.2e-93 312.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EKG21122.1 - 1.1e-37 129.7 0.8 2.5e-37 128.6 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EKG21122.1 - 7.2e-23 81.1 1.2 1.4e-22 80.1 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EKG21122.1 - 2.9e-19 69.1 0.0 1.2e-18 67.2 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EKG21122.1 - 3.9e-19 68.6 1.8 1.4e-18 66.8 1.2 2.0 1 0 0 1 1 1 1 MutS family domain IV ThiF PF00899.16 EKG21124.1 - 1.5e-28 99.3 0.0 2.4e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EKG21124.1 - 0.025 14.6 0.0 0.086 12.9 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Toprim PF01751.17 EKG21124.1 - 0.094 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Toprim domain AAA_17 PF13207.1 EKG21125.1 - 4.1e-05 24.3 0.1 6.3e-05 23.7 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EKG21125.1 - 0.00039 20.7 0.0 0.00073 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EKG21125.1 - 0.0006 19.2 0.0 0.0013 18.1 0.0 1.6 2 0 0 2 2 2 1 Dephospho-CoA kinase CobU PF02283.11 EKG21125.1 - 0.052 12.9 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Dynamin_N PF00350.18 EKG21125.1 - 0.057 13.2 0.0 0.069 12.9 0.0 1.2 1 1 0 1 1 1 0 Dynamin family AAA_33 PF13671.1 EKG21125.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain dCMP_cyt_deam_1 PF00383.17 EKG21126.1 - 1.1e-11 44.3 1.1 1.7e-11 43.6 0.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EKG21126.1 - 0.0086 15.7 0.2 0.012 15.3 0.2 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase SHNi-TPR PF10516.4 EKG21127.1 - 2.7e-15 55.3 0.2 7.7e-15 53.8 0.1 1.9 1 0 0 1 1 1 1 SHNi-TPR TPR_11 PF13414.1 EKG21127.1 - 2.2e-05 23.9 12.3 0.001 18.6 1.8 3.2 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EKG21127.1 - 0.0014 18.5 10.0 0.034 14.0 0.6 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EKG21127.1 - 0.002 18.7 1.0 0.002 18.7 0.7 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF848 PF05852.6 EKG21127.1 - 0.054 13.3 0.5 0.054 13.3 0.4 3.1 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) HpaB PF03241.8 EKG21127.1 - 0.095 11.5 0.0 0.22 10.3 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal FlaC_arch PF05377.6 EKG21127.1 - 0.096 12.5 3.2 0.2 11.5 1.4 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) AKNA PF12443.3 EKG21127.1 - 0.11 12.5 2.8 4.4 7.3 0.1 2.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor CCDC-167 PF15188.1 EKG21127.1 - 0.25 11.3 8.3 0.067 13.1 1.3 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 CENP-B_dimeris PF09026.5 EKG21127.1 - 0.31 11.2 5.4 1.5 9.1 3.8 2.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TMPIT PF07851.8 EKG21127.1 - 2.5 7.0 4.3 0.84 8.6 0.9 1.6 2 0 0 2 2 2 0 TMPIT-like protein DNA_pol_E_B PF04042.11 EKG21128.1 - 6.2e-49 166.0 0.0 9.3e-49 165.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B AA_permease PF00324.16 EKG21129.1 - 2.5e-131 438.3 48.5 3.1e-131 438.0 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG21129.1 - 2.8e-32 111.7 52.8 3.5e-32 111.5 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease Nop14 PF04147.7 EKG21130.1 - 0.0099 13.8 5.0 0.0097 13.8 3.4 1.0 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.8 EKG21130.1 - 0.17 11.4 9.0 0.22 11.1 6.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 EKG21130.1 - 0.45 8.4 9.4 0.54 8.2 6.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EKG21130.1 - 0.65 8.0 2.0 0.72 7.8 1.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Rubella_Capsid PF05750.6 EKG21130.1 - 2.1 7.7 5.1 2.7 7.3 3.5 1.1 1 0 0 1 1 1 0 Rubella capsid protein Sugar_tr PF00083.19 EKG21131.1 - 1.3e-116 389.8 27.8 1.7e-116 389.4 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG21131.1 - 1.5e-23 83.1 42.9 2.4e-16 59.4 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG21131.1 - 0.0031 15.9 30.1 0.0047 15.3 8.6 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein Peptidase_M28 PF04389.12 EKG21132.1 - 1.1e-34 119.7 0.0 3.1e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M28 zf-C2H2_4 PF13894.1 EKG21132.1 - 0.13 12.6 4.2 1.4 9.4 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Reo_sigmaC PF04582.7 EKG21134.1 - 0.00011 21.5 51.0 0.0028 16.8 2.2 6.3 3 2 3 7 7 7 5 Reovirus sigma C capsid protein IncA PF04156.9 EKG21134.1 - 0.0003 20.4 166.3 0.0064 16.1 17.3 8.7 2 1 5 7 7 7 4 IncA protein Spc7 PF08317.6 EKG21134.1 - 0.14 10.7 141.7 0.083 11.5 16.3 7.8 2 1 5 7 7 7 0 Spc7 kinetochore protein DUF3506 PF12014.3 EKG21135.1 - 2.2e-43 147.2 0.0 6.5e-42 142.5 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3506) Aldedh PF00171.17 EKG21138.1 - 4.2e-49 167.1 0.0 4.5e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_4 PF01565.18 EKG21139.1 - 6.8e-17 61.2 0.7 9.6e-17 60.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EKG21139.1 - 6.3e-10 39.0 0.0 6e-07 29.3 0.0 2.4 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase RRM_1 PF00076.17 EKG21140.1 - 1.1e-35 121.1 0.1 6.2e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG21140.1 - 2e-28 98.1 0.0 1.6e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG21140.1 - 2.2e-11 43.3 0.0 5.8e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BATS PF06968.8 EKG21140.1 - 0.062 13.1 0.6 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain RRM_3 PF08777.6 EKG21140.1 - 0.077 12.8 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.13 EKG21141.1 - 1.4e-47 161.9 0.0 4.2e-47 160.3 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain adh_short PF00106.20 EKG21142.1 - 1.4e-06 28.3 0.3 2.9e-06 27.3 0.0 1.6 2 1 0 2 2 2 1 short chain dehydrogenase MobA_MobL PF03389.10 EKG21142.1 - 0.044 13.1 0.0 0.056 12.8 0.0 1.1 1 0 0 1 1 1 0 MobA/MobL family Nitro_FeMo-Co PF02579.12 EKG21142.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Ank_2 PF12796.2 EKG21144.1 - 2.8e-09 37.1 0.2 1.5e-08 34.8 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EKG21144.1 - 0.0061 16.3 0.2 0.82 9.5 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EKG21144.1 - 0.0076 16.4 2.0 0.065 13.5 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RrnaAD PF00398.15 EKG21144.1 - 0.064 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ank_4 PF13637.1 EKG21144.1 - 0.1 13.1 1.3 9 6.9 0.1 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) SnoaL_2 PF12680.2 EKG21145.1 - 9.2e-06 26.0 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EKG21145.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase 2H-phosphodiest PF08975.5 EKG21147.1 - 0.083 12.6 0.0 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1868) MFS_1 PF07690.11 EKG21148.1 - 6e-11 41.6 29.8 8.5e-11 41.1 20.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG21148.1 - 2.3e-05 22.9 15.0 2.3e-05 22.9 10.4 1.6 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EKG21148.1 - 0.0008 18.0 18.3 0.0013 17.3 12.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EKG21148.1 - 0.89 9.3 9.4 0.16 11.7 1.5 2.7 3 0 0 3 3 3 0 MFS_1 like family GFO_IDH_MocA PF01408.17 EKG21149.1 - 9.6e-17 61.6 0.0 2.9e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold VTC PF09359.5 EKG21150.1 - 2.3e-101 338.5 0.3 2.3e-101 338.5 0.2 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EKG21150.1 - 3.1e-28 99.3 7.5 1.8e-25 90.2 5.2 3.1 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 EKG21150.1 - 2.7e-11 43.5 4.6 5.6e-11 42.5 3.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) DUF4164 PF13747.1 EKG21150.1 - 0.07 13.2 0.3 0.07 13.2 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DLH PF01738.13 EKG21151.1 - 3e-31 108.4 0.0 3.4e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG21151.1 - 5.8e-08 32.6 0.0 8.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG21151.1 - 0.0013 18.6 0.0 0.013 15.3 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 EKG21151.1 - 0.054 12.5 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Glyco_hydro_cc PF11790.3 EKG21153.1 - 5.9e-71 238.6 0.8 6.7e-71 238.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core MFS_1 PF07690.11 EKG21154.1 - 6.5e-15 54.6 36.7 3.1e-14 52.4 25.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21154.1 - 0.0002 20.0 7.7 0.0002 20.0 5.4 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter HET PF06985.6 EKG21156.1 - 1.6e-16 60.7 0.0 5e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TRP PF06011.7 EKG21158.1 - 3.2e-139 464.2 6.4 3.9e-139 464.0 4.5 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EKG21158.1 - 9.3e-34 116.4 0.3 1.5e-33 115.7 0.2 1.4 1 0 0 1 1 1 1 ML-like domain Shisa PF13908.1 EKG21158.1 - 0.078 13.1 0.1 0.078 13.1 0.1 2.1 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator FAM176 PF14851.1 EKG21158.1 - 0.18 11.4 0.5 5.4 6.6 0.0 2.6 3 0 0 3 3 3 0 FAM176 family TMEM154 PF15102.1 EKG21158.1 - 0.52 10.0 3.8 5.3 6.7 0.9 2.4 2 0 0 2 2 2 0 TMEM154 protein family EphA2_TM PF14575.1 EKG21158.1 - 0.79 10.1 0.0 0.79 10.1 0.0 4.1 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain CRT-like PF08627.5 EKG21158.1 - 2.8 7.8 6.1 0.37 10.7 0.1 2.5 2 0 0 2 2 2 0 CRT-like DNA_methylase PF00145.12 EKG21159.1 - 1.5e-33 116.3 0.0 3.8e-33 115.0 0.0 1.7 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EKG21159.1 - 0.00028 20.6 0.1 0.0026 17.4 0.1 2.1 2 0 0 2 2 2 1 BAH domain TPR_14 PF13428.1 EKG21160.1 - 2.6e-15 55.5 7.3 0.031 14.9 0.0 7.7 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EKG21160.1 - 1e-12 48.3 11.5 0.00012 22.5 0.2 5.8 3 1 4 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EKG21160.1 - 1.3e-12 47.1 1.1 0.0023 17.5 0.0 6.1 3 2 3 6 6 6 4 TPR repeat TPR_19 PF14559.1 EKG21160.1 - 4.9e-11 42.8 4.4 0.48 10.8 0.0 7.0 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.1 EKG21160.1 - 1.3e-08 34.2 7.5 0.047 12.7 0.2 4.2 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EKG21160.1 - 1.6e-08 33.7 7.2 0.59 10.1 0.0 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EKG21160.1 - 1.5e-05 24.3 0.0 2.9 7.8 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 EKG21160.1 - 3.6e-05 22.7 0.1 3.3 6.3 0.0 4.2 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 TPR_1 PF00515.23 EKG21160.1 - 0.00025 20.5 0.3 2.1 8.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EKG21160.1 - 0.00027 20.5 0.2 15 5.7 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Suf PF05843.9 EKG21160.1 - 0.0003 20.6 0.0 1 9.0 0.0 3.2 1 1 0 3 3 3 1 Suppressor of forked protein (Suf) FAT PF02259.18 EKG21160.1 - 0.0008 18.4 0.2 0.031 13.2 0.1 2.6 2 1 0 2 2 2 1 FAT domain TPR_17 PF13431.1 EKG21160.1 - 0.0019 18.2 0.5 3.7 7.9 0.0 5.5 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKG21160.1 - 0.002 17.9 8.1 1.5 8.8 0.0 5.8 4 3 2 6 6 6 1 Tetratricopeptide repeat Cutinase PF01083.17 EKG21160.1 - 0.11 12.1 0.0 0.82 9.3 0.0 2.5 3 1 0 3 3 3 0 Cutinase PfkB PF00294.19 EKG21161.1 - 1.9e-08 33.8 0.1 2.8e-08 33.2 0.1 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Indigoidine_A PF04227.7 EKG21162.1 - 6.5e-116 386.6 0.8 7.6e-116 386.4 0.5 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Ribophorin_I PF04597.9 EKG21163.1 - 2.5e-156 520.5 0.0 2.9e-156 520.3 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I AA_permease_2 PF13520.1 EKG21164.1 - 3.9e-38 131.1 42.8 4.8e-38 130.8 29.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG21164.1 - 7.3e-26 90.5 40.3 1e-25 90.0 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.1 EKG21165.1 - 4.9e-21 75.7 0.0 1e-19 71.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EKG21165.1 - 1.2e-16 60.0 0.2 5e-15 54.6 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EKG21165.1 - 3.4e-11 42.9 0.0 2.1e-10 40.4 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EKG21165.1 - 1e-06 27.9 0.1 4e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EKG21165.1 - 5.6e-06 26.2 0.0 0.003 17.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EKG21165.1 - 0.019 13.8 0.1 6.5 5.5 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase PXA PF02194.10 EKG21166.1 - 6.1e-40 136.7 0.1 6.1e-40 136.7 0.0 2.6 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EKG21166.1 - 1.1e-18 67.4 0.0 1.1e-18 67.4 0.0 2.9 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 EKG21166.1 - 0.00016 21.4 0.0 0.00093 18.9 0.0 2.4 1 1 0 1 1 1 1 PX domain Ank_2 PF12796.2 EKG21167.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) 4HBT PF03061.17 EKG21168.1 - 1.5e-12 47.4 0.1 2.4e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EKG21168.1 - 0.021 14.8 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Abhydrolase_3 PF07859.8 EKG21169.1 - 1.2e-29 103.3 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG21169.1 - 6.1e-05 22.8 0.0 7.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EKG21169.1 - 0.00026 19.9 0.0 0.00038 19.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 EKG21169.1 - 0.0015 17.3 0.0 0.003 16.3 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 EKG21169.1 - 0.0023 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EKG21169.1 - 0.022 14.0 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EKG21169.1 - 0.038 13.5 0.0 0.043 13.3 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4166 PF13761.1 EKG21169.1 - 0.094 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4166) WD40 PF00400.27 EKG21170.1 - 1.2e-26 91.5 20.4 2.4e-08 33.5 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 EKG21171.1 - 1.4e-32 113.0 0.0 2.1e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EKG21171.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily COG4 PF08318.7 EKG21172.1 - 9.9e-98 326.9 0.0 1.4e-97 326.4 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein TMF_TATA_bd PF12325.3 EKG21172.1 - 0.38 10.4 3.1 3.2 7.4 0.1 2.6 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Mg_trans_NIPA PF05653.9 EKG21173.1 - 2.2e-91 305.9 26.9 3.1e-91 305.4 18.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EKG21173.1 - 9e-06 25.8 5.0 9e-06 25.8 3.5 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EKG21173.1 - 2.8e-05 24.1 6.4 2.8e-05 24.1 4.4 3.6 3 1 1 4 4 4 1 EamA-like transporter family DUF4314 PF14192.1 EKG21174.1 - 0.036 14.3 2.3 0.08 13.2 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4314) Tyrosinase PF00264.15 EKG21176.1 - 2.4e-55 188.1 8.5 3.5e-55 187.5 5.9 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase MCM PF00493.18 EKG21177.1 - 2.4e-139 463.7 0.0 3.3e-139 463.3 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EKG21177.1 - 2.5e-23 82.8 0.0 1.7e-22 80.1 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EKG21177.1 - 4e-06 26.5 0.1 2.1e-05 24.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EKG21177.1 - 9.5e-06 24.9 0.0 0.00039 19.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EKG21177.1 - 0.001 18.6 0.0 0.003 17.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EKG21177.1 - 0.079 12.4 0.1 4.4 6.7 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DSX_dimer PF08828.5 EKG21177.1 - 0.89 9.1 9.9 0.56 9.7 0.1 3.7 4 0 0 4 4 4 0 Doublesex dimerisation domain TBCA PF02970.11 EKG21178.1 - 3.8e-25 87.7 10.2 4.8e-25 87.4 7.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF342 PF03961.8 EKG21178.1 - 0.00012 20.6 7.6 0.00014 20.4 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) TEBP_beta PF07404.6 EKG21178.1 - 0.0013 17.9 1.9 0.0013 17.9 1.3 1.0 1 0 0 1 1 1 1 Telomere-binding protein beta subunit (TEBP beta) IncA PF04156.9 EKG21178.1 - 0.0016 18.0 6.5 0.0018 17.9 4.5 1.1 1 0 0 1 1 1 1 IncA protein DUF3450 PF11932.3 EKG21178.1 - 0.0078 15.5 6.2 0.0091 15.2 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Mnd1 PF03962.10 EKG21178.1 - 0.01 15.5 8.5 0.015 14.9 5.9 1.3 1 0 0 1 1 1 0 Mnd1 family DUF4175 PF13779.1 EKG21178.1 - 0.011 13.5 6.1 0.012 13.4 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Dynamin_M PF01031.15 EKG21178.1 - 0.032 13.0 1.1 0.042 12.6 0.7 1.3 1 1 0 1 1 1 0 Dynamin central region Spc7 PF08317.6 EKG21178.1 - 0.07 11.7 8.5 0.093 11.3 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.1 EKG21178.1 - 0.1 12.8 8.5 0.15 12.3 5.9 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin PF00804.20 EKG21178.1 - 0.11 12.6 5.6 0.15 12.2 3.9 1.2 1 0 0 1 1 1 0 Syntaxin ADIP PF11559.3 EKG21178.1 - 0.14 12.0 9.1 0.08 12.8 4.7 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4559 PF15112.1 EKG21178.1 - 0.16 11.0 3.6 0.2 10.8 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) bZIP_Maf PF03131.12 EKG21178.1 - 0.28 11.5 4.3 0.94 9.8 3.0 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor AAA_13 PF13166.1 EKG21178.1 - 0.33 9.3 7.3 0.42 9.0 5.1 1.2 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 EKG21178.1 - 0.34 11.3 4.3 0.51 10.7 3.0 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Muted PF14942.1 EKG21178.1 - 0.36 10.7 7.4 1.9 8.3 1.0 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Toxin_39 PF15500.1 EKG21178.1 - 0.45 10.6 5.0 1.5 8.9 3.5 1.9 1 1 0 1 1 1 0 Putative RNase-like toxin Halogen_Hydrol PF10112.4 EKG21178.1 - 0.63 9.4 3.6 0.43 9.9 0.5 1.9 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein V_ATPase_I PF01496.14 EKG21178.1 - 0.63 7.8 3.8 0.69 7.6 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 EKG21178.1 - 0.8 8.6 8.4 0.98 8.3 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TBPIP PF07106.8 EKG21178.1 - 0.83 9.1 9.6 5.8 6.4 2.0 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BTV_NS2 PF04514.7 EKG21178.1 - 0.94 8.2 5.6 1.1 8.0 3.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CENP-Q PF13094.1 EKG21178.1 - 1.1 9.2 12.7 2.8 7.9 8.8 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Fmp27_WPPW PF10359.4 EKG21178.1 - 1.2 7.5 6.0 1.2 7.4 4.1 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HlyD PF00529.15 EKG21178.1 - 1.3 8.2 11.3 1.6 7.9 7.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF4337 PF14235.1 EKG21178.1 - 1.9 8.2 12.7 4.5 7.0 7.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Spectrin PF00435.16 EKG21178.1 - 2 8.7 9.1 3.6 7.9 5.5 1.9 1 1 1 2 2 2 0 Spectrin repeat APG6 PF04111.7 EKG21178.1 - 2.1 7.3 9.0 2.4 7.1 6.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Ax_dynein_light PF10211.4 EKG21178.1 - 2.3 8.0 10.7 0.4 10.5 2.7 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain Wbp11 PF09429.5 EKG21178.1 - 2.7 8.0 12.2 1.1 9.2 4.1 2.3 1 1 0 2 2 2 0 WW domain binding protein 11 DUF2570 PF10828.3 EKG21178.1 - 3.9 7.1 8.2 9.3 5.9 5.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Herpes_UL25 PF01499.11 EKG21178.1 - 4.6 5.4 7.6 4.7 5.4 5.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family GrpE PF01025.14 EKG21178.1 - 4.6 6.7 12.0 7.6 6.0 8.3 1.4 1 1 0 1 1 1 0 GrpE Remorin_C PF03763.8 EKG21178.1 - 4.7 6.7 12.1 8.5 5.9 8.4 1.4 1 1 0 1 1 1 0 Remorin, C-terminal region OmpH PF03938.9 EKG21178.1 - 5.3 6.9 14.5 19 5.1 10.1 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.4 EKG21178.1 - 6.5 6.9 7.3 6.2 7.0 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF883 PF05957.8 EKG21178.1 - 7 7.1 8.0 62 4.0 4.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Spc24 PF08286.6 EKG21178.1 - 7.7 6.2 9.7 4.9 6.8 2.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF3661 PF12400.3 EKG21179.1 - 1.8e-43 147.6 1.8 2.6e-43 147.1 1.3 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein HATPase_c PF02518.21 EKG21180.1 - 1.2e-25 89.4 0.5 2.2e-25 88.5 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.6 EKG21180.1 - 1.5e-21 76.2 1.6 3.7e-11 42.9 0.5 3.5 3 0 0 3 3 3 3 PAS fold HisKA PF00512.20 EKG21180.1 - 1.8e-20 72.6 0.5 4.8e-20 71.3 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EKG21180.1 - 1.9e-19 69.6 0.2 1e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EKG21180.1 - 7.6e-16 58.3 0.0 8.3e-09 35.7 0.0 3.3 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 EKG21180.1 - 1.7e-15 56.7 0.0 1.8e-06 27.6 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EKG21180.1 - 1.9e-11 43.9 0.3 2.8e-08 33.7 0.0 3.1 3 0 0 3 3 3 2 PAS fold Mo25 PF08569.6 EKG21181.1 - 3.5e-128 427.3 0.1 4e-128 427.1 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Pkinase PF00069.20 EKG21182.1 - 4.6e-43 147.2 0.0 5.6e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21182.1 - 1.4e-16 60.4 0.0 1.7e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG21182.1 - 4.6e-06 25.7 0.0 7.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EKG21182.1 - 2.7e-05 24.0 0.1 0.53 9.9 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family WPP PF13943.1 EKG21182.1 - 0.032 14.4 0.1 0.083 13.1 0.1 1.6 1 0 0 1 1 1 0 WPP domain YrbL-PhoP_reg PF10707.4 EKG21182.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL muHD PF10291.4 EKG21183.1 - 1.1e-75 254.1 0.0 1.5e-75 253.7 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain zf-RING_2 PF13639.1 EKG21184.1 - 1e-08 34.8 6.9 1.9e-08 33.9 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKG21184.1 - 5.8e-07 29.5 3.9 1.3e-06 28.3 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EKG21184.1 - 1.4e-05 24.9 5.3 1.4e-05 24.9 3.7 2.0 2 0 0 2 2 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EKG21184.1 - 0.00014 21.6 1.4 0.0003 20.5 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EKG21184.1 - 0.00021 20.9 2.2 0.00021 20.9 1.5 1.6 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 EKG21184.1 - 0.00097 19.1 7.3 0.002 18.1 5.1 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 EKG21184.1 - 0.0028 17.2 9.1 0.0063 16.1 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EKG21184.1 - 0.0085 16.1 8.8 0.017 15.1 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF883 PF05957.8 EKG21184.1 - 0.031 14.6 0.0 1.4 9.4 0.0 3.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Baculo_RING PF05883.6 EKG21184.1 - 0.22 11.3 0.8 0.57 10.0 0.5 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_3 PF13920.1 EKG21184.1 - 0.23 11.1 5.0 0.47 10.1 3.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EKG21184.1 - 0.75 9.5 5.8 1.3 8.7 4.0 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EKG21184.1 - 1 9.4 6.2 1.9 8.5 4.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EKG21184.1 - 1.5 8.4 5.4 30 4.3 3.8 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1227 PF06777.6 EKG21185.1 - 6.3e-62 207.5 0.6 1.6e-61 206.2 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EKG21185.1 - 4.4e-52 176.0 0.2 9.2e-52 174.9 0.1 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EKG21185.1 - 1.4e-44 151.9 0.0 3.7e-44 150.6 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain SNF2_N PF00176.18 EKG21185.1 - 4.7e-05 22.3 0.0 0.00026 19.9 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EKG21185.1 - 6.6e-05 22.4 0.0 0.0085 15.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EKG21185.1 - 0.012 15.3 0.0 0.048 13.4 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EKG21185.1 - 0.025 14.1 0.2 0.062 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EKG21185.1 - 0.048 12.6 0.0 1.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EKG21185.1 - 0.13 11.4 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PRP3 PF08572.5 EKG21186.1 - 7.1e-65 218.5 7.4 1.6e-64 217.3 5.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EKG21186.1 - 1.3e-36 125.1 2.8 1.3e-36 125.1 2.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EKG21187.1 - 3.1e-93 312.0 0.0 1.2e-92 310.1 0.0 2.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EKG21187.1 - 6.9e-62 208.2 0.1 1.5e-61 207.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EKG21187.1 - 4.3e-31 107.7 0.0 1.4e-30 106.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EKG21187.1 - 5.1e-31 108.1 7.1 2e-19 70.0 0.0 3.8 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EKG21187.1 - 1.7e-16 59.8 0.0 1.3e-15 57.0 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 AAA PF00004.24 EKG21188.1 - 1.4e-17 64.0 0.0 3.3e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zot PF05707.7 EKG21188.1 - 0.0019 17.6 0.3 0.026 13.9 0.2 2.4 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EKG21188.1 - 0.0081 16.3 1.2 0.37 10.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EKG21188.1 - 0.0092 15.9 2.0 0.032 14.2 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EKG21188.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKG21188.1 - 0.053 14.3 3.1 0.46 11.3 0.9 3.4 2 2 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EKG21188.1 - 0.056 13.1 0.1 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EKG21188.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PSP PF04046.11 EKG21188.1 - 0.092 12.1 0.1 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 PSP AAA_19 PF13245.1 EKG21188.1 - 0.096 12.4 0.4 0.24 11.1 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EKG21188.1 - 3.2 8.0 5.5 2.6 8.3 0.0 3.2 3 1 0 3 3 3 0 AAA domain Ras PF00071.17 EKG21189.1 - 3.1e-52 176.2 0.2 2.5e-51 173.2 0.1 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EKG21189.1 - 5.5e-18 65.5 0.0 5.9e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EKG21189.1 - 0.00023 20.4 0.0 0.00056 19.2 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EKG21189.1 - 0.0084 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EKG21189.1 - 0.026 13.9 0.1 3.2 7.1 0.0 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EKG21189.1 - 0.066 12.4 0.0 0.68 9.1 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 EKG21189.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EKG21189.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin Gtr1_RagA PF04670.7 EKG21189.1 - 0.12 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AMP-binding PF00501.23 EKG21190.1 - 6.2e-78 262.0 0.0 7.4e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG21190.1 - 1.4e-15 57.9 1.0 2.7e-15 57.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Acetyltransf_2 PF00797.12 EKG21191.1 - 8.6e-38 130.2 0.0 1.7e-37 129.2 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 EKG21191.1 - 0.00056 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily HAD_2 PF13419.1 EKG21192.1 - 3.2e-22 79.5 0.1 1.2e-21 77.7 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG21192.1 - 1.6e-05 25.4 0.0 2.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EKG21192.1 - 0.00046 19.8 0.0 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like DUF3368 PF11848.3 EKG21192.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) FUSC_2 PF13515.1 EKG21193.1 - 9.9e-30 103.0 3.0 9.9e-30 103.0 2.1 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EKG21193.1 - 1.1e-06 28.4 0.0 3.5e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EKG21193.1 - 1.5e-06 27.1 15.6 0.029 13.0 0.5 4.4 5 0 0 5 5 5 3 Aluminium activated malate transporter FUSC PF04632.7 EKG21193.1 - 8e-06 24.5 12.1 0.00041 18.9 3.2 3.1 2 1 0 2 2 2 2 Fusaric acid resistance protein family MPLKIP PF15502.1 EKG21194.1 - 0.00025 21.7 5.9 0.0023 18.6 4.1 2.4 1 1 0 1 1 1 1 M-phase-specific PLK1-interacting protein KxDL PF10241.4 EKG21195.1 - 5.1e-31 106.4 1.1 6.7e-31 106.0 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2285 PF10074.4 EKG21195.1 - 0.042 14.1 1.8 0.061 13.6 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) AAA PF00004.24 EKG21196.1 - 5.6e-55 185.1 0.0 1.2e-38 132.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG21196.1 - 1.3e-11 44.7 0.4 0.0016 18.5 0.0 4.2 2 2 0 2 2 2 2 AAA domain CDC48_N PF02359.13 EKG21196.1 - 8.1e-11 41.7 0.0 1.9e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 EKG21196.1 - 6.5e-10 39.8 0.0 0.0017 19.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EKG21196.1 - 1.9e-09 37.7 0.3 0.0018 18.3 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain CDC48_2 PF02933.12 EKG21196.1 - 2e-09 36.9 0.1 2.7e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 EKG21196.1 - 5.6e-09 35.6 2.5 0.0027 17.4 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain AAA_14 PF13173.1 EKG21196.1 - 7e-09 35.6 0.0 0.00028 20.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EKG21196.1 - 2.8e-08 34.1 0.2 0.005 17.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 EKG21196.1 - 3e-08 32.7 0.0 0.0044 15.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 EKG21196.1 - 3.9e-08 33.1 0.0 0.0023 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EKG21196.1 - 6.4e-08 32.5 0.0 0.0062 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EKG21196.1 - 3e-07 30.5 0.1 9.8e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EKG21196.1 - 4.1e-07 29.2 0.4 0.02 13.9 0.0 3.1 3 1 1 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EKG21196.1 - 1.4e-06 27.6 0.1 0.0088 15.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EKG21196.1 - 2.7e-06 26.9 0.1 0.089 12.2 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EKG21196.1 - 6.5e-06 26.2 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EKG21196.1 - 7.8e-06 25.6 0.7 0.025 14.2 0.0 3.1 3 1 0 3 3 3 2 NACHT domain KaiC PF06745.8 EKG21196.1 - 7.9e-06 25.1 0.4 0.0089 15.1 0.1 2.6 3 0 0 3 3 2 2 KaiC AAA_28 PF13521.1 EKG21196.1 - 2.1e-05 24.5 0.0 0.085 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EKG21196.1 - 3.3e-05 23.0 0.1 0.17 10.9 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 EKG21196.1 - 0.00014 22.1 0.4 0.045 14.0 0.1 2.7 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 EKG21196.1 - 0.00014 21.2 1.3 0.39 10.1 0.0 3.3 3 1 1 4 4 4 2 AAA domain KTI12 PF08433.5 EKG21196.1 - 0.00033 19.9 0.0 0.7 9.0 0.0 2.3 2 0 0 2 2 2 2 Chromatin associated protein KTI12 PhoH PF02562.11 EKG21196.1 - 0.00034 19.9 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 EKG21196.1 - 0.00041 19.9 0.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EKG21196.1 - 0.00044 19.8 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EKG21196.1 - 0.0006 18.7 0.1 0.82 8.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.4 EKG21196.1 - 0.00072 18.6 0.0 0.26 10.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EKG21196.1 - 0.001 18.7 0.6 0.74 9.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EKG21196.1 - 0.0011 18.4 0.0 0.5 9.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.1 EKG21196.1 - 0.0012 18.4 0.0 0.35 10.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EKG21196.1 - 0.0013 18.3 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EKG21196.1 - 0.012 15.3 0.8 6.5 6.3 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase Viral_helicase1 PF01443.13 EKG21196.1 - 0.014 14.8 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Torsin PF06309.6 EKG21196.1 - 0.018 14.9 0.0 7.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Torsin ResIII PF04851.10 EKG21196.1 - 0.019 14.8 0.2 6.5 6.5 0.2 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit cobW PF02492.14 EKG21196.1 - 0.028 13.8 0.4 1.3 8.4 0.0 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activ_2 PF14532.1 EKG21196.1 - 0.043 13.8 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 EKG21196.1 - 0.046 13.3 0.0 4.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DEAD PF00270.24 EKG21196.1 - 0.049 13.1 0.8 37 3.7 0.0 4.0 3 2 1 5 5 5 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.12 EKG21196.1 - 0.053 12.3 0.0 1.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 T2SE PF00437.15 EKG21196.1 - 0.065 12.1 0.0 3.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.4 EKG21196.1 - 0.11 11.3 0.1 3.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF4220 PF13968.1 EKG21196.1 - 0.14 11.2 0.1 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) TrwB_AAD_bind PF10412.4 EKG21196.1 - 0.19 10.3 0.2 1.3 7.5 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Myb_DNA-bind_6 PF13921.1 EKG21197.1 - 1.6e-13 50.5 8.8 1.7e-09 37.5 0.1 4.5 3 1 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EKG21197.1 - 2.2e-13 50.0 7.7 1.4e-09 37.8 0.0 3.8 5 0 0 5 5 5 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 EKG21197.1 - 5 7.3 19.1 0.54 10.4 0.4 5.3 5 0 0 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Fringe PF02434.11 EKG21198.1 - 0.00012 21.3 2.1 0.0007 18.8 1.0 2.3 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 EKG21198.1 - 0.0089 15.7 3.3 0.021 14.5 2.3 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EKG21198.1 - 0.098 12.4 0.4 0.17 11.6 0.2 1.3 1 0 0 1 1 1 0 PAN domain Acylphosphatase PF00708.13 EKG21200.1 - 3.7e-28 97.4 0.3 4e-28 97.3 0.2 1.0 1 0 0 1 1 1 1 Acylphosphatase PTA_PTB PF01515.14 EKG21200.1 - 0.015 14.3 0.0 0.016 14.2 0.0 1.0 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase KAR9 PF08580.5 EKG21202.1 - 6.1e-116 388.3 1.9 8.8e-116 387.8 1.3 1.2 1 0 0 1 1 1 1 Yeast cortical protein KAR9 Tropomyosin_1 PF12718.2 EKG21202.1 - 0.073 12.9 0.1 0.073 12.9 0.0 2.7 3 0 0 3 3 3 0 Tropomyosin like Vac_Fusion PF02346.11 EKG21202.1 - 0.11 11.9 0.8 0.39 10.1 0.2 2.1 2 0 0 2 2 2 0 Chordopoxvirus fusion protein IncA PF04156.9 EKG21202.1 - 0.25 10.9 2.9 0.95 9.0 0.4 2.6 2 0 0 2 2 2 0 IncA protein Spectrin PF00435.16 EKG21202.1 - 1.7 8.9 8.0 5.4 7.3 0.2 3.8 3 1 0 3 3 3 0 Spectrin repeat Kelch_5 PF13854.1 EKG21203.1 - 1.6e-18 66.1 18.7 5.2e-10 39.0 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EKG21203.1 - 1.1e-14 54.0 15.0 5.2e-06 26.4 0.1 6.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EKG21203.1 - 3.9e-14 52.1 21.2 0.00022 20.9 0.5 6.5 5 1 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EKG21203.1 - 4.6e-11 42.3 16.6 0.00044 20.2 0.4 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EKG21203.1 - 7.3e-07 28.7 6.9 0.0017 18.0 0.2 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EKG21203.1 - 5.2e-05 22.7 14.5 0.015 14.8 0.5 4.9 6 0 0 6 6 6 2 Kelch motif Nucleo_P87 PF07267.6 EKG21203.1 - 0.051 12.2 0.3 0.086 11.5 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ADH_zinc_N PF00107.21 EKG21204.1 - 2.4e-17 62.6 0.1 3.3e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG21204.1 - 1.1e-12 48.8 0.0 1.6e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AT_hook PF02178.14 EKG21205.1 - 0.054 13.1 6.0 0.14 11.8 4.1 1.8 1 0 0 1 1 1 0 AT hook motif FmdA_AmdA PF03069.10 EKG21206.1 - 4.7e-157 522.4 0.0 5.4e-157 522.2 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 EKG21207.1 - 2.3e-06 27.1 9.3 0.00012 21.6 6.5 2.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.19 EKG21207.1 - 0.063 12.7 0.1 0.5 9.7 0.0 2.2 1 1 1 2 2 2 0 Fatty acid desaturase Beta_helix PF13229.1 EKG21208.1 - 4.7e-11 42.6 19.9 3.3e-07 30.1 1.3 2.5 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.1 EKG21208.1 - 4.1e-07 29.1 0.0 8.3e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.6 EKG21208.1 - 0.0012 18.0 0.6 0.0012 18.0 0.4 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) Glyco_trans_1_4 PF13692.1 EKG21209.1 - 3e-26 92.1 0.0 2.8e-24 85.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EKG21209.1 - 6.6e-10 39.3 0.8 1.2e-09 38.5 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EKG21209.1 - 3.4e-06 26.5 0.0 0.00046 19.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Cation_efflux PF01545.16 EKG21210.1 - 3.6e-54 183.7 5.8 3.6e-54 183.7 4.0 2.8 3 0 0 3 3 3 1 Cation efflux family TRP_2 PF08344.6 EKG21210.1 - 0.029 14.2 0.0 12 5.9 0.0 2.6 2 0 0 2 2 2 0 Transient receptor ion channel II TFIIIC_delta PF12657.2 EKG21212.1 - 7e-23 81.2 0.3 1.1e-21 77.2 0.1 2.3 2 0 0 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EKG21212.1 - 1.3e-20 73.1 0.4 1.3e-19 69.9 0.3 2.3 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex adh_short PF00106.20 EKG21212.1 - 3e-18 66.2 0.0 5.9e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG21212.1 - 1.3e-17 64.4 0.0 2.2e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sec23_trunk PF04811.10 EKG21214.1 - 1.5e-57 194.7 0.0 1.4e-56 191.5 0.0 2.2 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EKG21214.1 - 9.4e-27 92.4 0.0 1.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EKG21214.1 - 9.4e-18 64.5 0.0 1.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EKG21214.1 - 7e-17 60.7 5.4 1.8e-16 59.4 3.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EKG21214.1 - 2e-07 30.6 0.0 4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat SLS PF14611.1 EKG21214.1 - 0.0057 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Ribosomal_L18e PF00828.14 EKG21215.1 - 1.7e-26 93.0 0.1 1.7e-26 93.0 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Dimerisation PF08100.6 EKG21215.1 - 0.14 12.0 0.1 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain Mito_carr PF00153.22 EKG21216.1 - 1.3e-63 210.7 3.3 3.8e-24 84.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein AIRC PF00731.15 EKG21217.1 - 7e-61 203.9 0.7 1.2e-60 203.0 0.5 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EKG21217.1 - 2.3e-56 189.8 0.0 4.1e-56 189.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EKG21217.1 - 1.8e-11 44.1 0.0 4.2e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EKG21217.1 - 0.00022 20.6 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EKG21217.1 - 0.00046 19.5 0.0 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EKG21217.1 - 0.021 14.6 0.0 0.048 13.5 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain Clat_adaptor_s PF01217.15 EKG21220.1 - 7.1e-14 51.7 0.0 1.9e-12 47.1 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain FbpA PF05833.6 EKG21221.1 - 3.4e-37 128.0 11.8 3.4e-37 128.0 8.2 2.4 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 EKG21221.1 - 1.7e-32 111.3 0.0 1.7e-32 111.3 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EKG21221.1 - 1.3e-20 73.1 0.0 2.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Cad PF03596.8 EKG21222.1 - 2.7e-30 105.5 3.9 1.3e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Cadmium resistance transporter Frag1 PF10277.4 EKG21222.1 - 0.006 16.0 1.5 0.006 16.0 1.0 2.0 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family p450 PF00067.17 EKG21223.1 - 0.00039 19.0 0.0 0.00042 18.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_2 PF12681.2 EKG21224.1 - 4.8e-11 43.2 0.0 6.1e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EKG21224.1 - 4.4e-10 39.6 0.0 1e-09 38.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EKG21224.1 - 2.6e-05 24.1 0.0 3.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EKG21224.1 - 0.00016 21.6 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Ribosomal_L19e PF01280.15 EKG21225.1 - 4.5e-62 208.2 9.3 4.5e-62 208.2 6.5 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EKG21225.1 - 0.033 13.4 1.7 0.037 13.2 1.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4239 PF14023.1 EKG21225.1 - 0.094 12.0 1.1 0.14 11.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ist1 PF03398.9 EKG21226.1 - 5.1e-63 211.3 1.0 6.4e-63 211.0 0.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cir_N PF10197.4 EKG21227.1 - 0.039 13.9 0.2 0.039 13.9 0.1 3.6 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR Daxx PF03344.10 EKG21228.1 - 0.64 8.4 7.0 0.8 8.1 4.8 1.1 1 0 0 1 1 1 0 Daxx Family Aldedh PF00171.17 EKG21229.1 - 1e-156 521.8 0.2 1.2e-156 521.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family adh_short PF00106.20 EKG21230.1 - 3.9e-33 114.7 1.7 4.8e-33 114.4 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG21230.1 - 6.1e-30 104.7 0.0 7.8e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG21230.1 - 3.5e-09 36.5 0.2 5.1e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG21230.1 - 0.00039 19.9 0.2 0.00092 18.7 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EKG21230.1 - 0.0048 15.6 0.1 0.0063 15.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CH PF00307.26 EKG21231.1 - 2.7e-65 217.1 0.0 2.9e-19 69.0 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EKG21231.1 - 7e-06 26.0 0.3 8.5e-05 22.6 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EKG21231.1 - 0.0002 20.9 0.0 2.7 7.7 0.0 3.6 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_1 PF00036.27 EKG21231.1 - 0.0016 17.6 0.4 4.2 6.9 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EKG21231.1 - 0.076 12.9 3.2 0.53 10.2 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain NifU_N PF01592.11 EKG21232.1 - 1.1e-42 144.9 0.1 1.3e-42 144.7 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.24 EKG21233.1 - 1.2e-41 142.6 0.0 2.4e-41 141.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EKG21233.1 - 2.1e-22 79.0 17.7 2.1e-19 69.3 0.7 3.4 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EKG21233.1 - 1.6e-21 75.5 0.0 6.8e-10 38.4 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EKG21233.1 - 3.6e-20 72.5 0.0 4e-19 69.1 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UPF1_Zn_bind PF09416.5 EKG21233.1 - 0.0026 17.3 1.7 0.3 10.6 0.3 2.9 2 0 0 2 2 2 2 RNA helicase (UPF2 interacting domain) UBA_4 PF14555.1 EKG21233.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain FAD_binding_4 PF01565.18 EKG21234.1 - 3.9e-19 68.4 0.4 3.9e-19 68.4 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EKG21234.1 - 2e-13 49.9 0.0 4.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EKG21234.1 - 0.2 10.7 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DNA_pol_phi PF04931.8 EKG21235.1 - 2.1e-70 237.5 11.9 2.1e-70 237.5 8.2 1.4 2 0 0 2 2 2 1 DNA polymerase phi DUF2201_N PF13203.1 EKG21235.1 - 3.6 6.6 11.2 18 4.4 5.3 3.3 4 0 0 4 4 4 0 Putative metallopeptidase domain Daxx PF03344.10 EKG21235.1 - 5.4 5.3 25.0 11 4.2 17.4 1.5 1 0 0 1 1 1 0 Daxx Family Rhodanese PF00581.15 EKG21236.1 - 2.4e-12 47.1 0.0 5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain DLH PF01738.13 EKG21238.1 - 5.6e-16 58.4 0.0 4.5e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EKG21238.1 - 2.3e-09 37.1 0.0 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EKG21238.1 - 0.003 17.4 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG21238.1 - 0.0034 16.8 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Rep_fac-A_C PF08646.5 EKG21239.1 - 2e-54 183.2 5.4 5e-52 175.4 2.7 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EKG21239.1 - 2.1e-21 75.5 0.7 4.2e-21 74.6 0.1 1.8 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EKG21239.1 - 6.4e-14 51.5 0.2 2.5e-10 40.0 0.0 3.5 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.9 EKG21239.1 - 0.0026 17.8 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF223 1-cysPrx_C PF10417.4 EKG21240.1 - 1.8e-15 56.3 0.3 2.7e-15 55.7 0.2 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.16 EKG21240.1 - 1.4e-10 40.9 0.1 2e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKG21240.1 - 0.033 13.7 0.1 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Redoxin AD PF09793.4 EKG21241.1 - 8e-20 70.4 0.0 1.3e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Herpes_BLLF1 PF05109.8 EKG21241.1 - 0.023 12.6 0.2 0.024 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) 6PGD PF00393.14 EKG21242.1 - 3.5e-134 446.5 0.0 4.5e-134 446.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EKG21242.1 - 1e-49 168.5 0.0 1.4e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EKG21242.1 - 0.0068 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 EKG21242.1 - 0.097 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.17 EKG21243.1 - 3e-18 65.2 0.0 5.4e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG21243.1 - 4.8e-10 39.2 0.0 8.2e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG21243.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EKG21243.1 - 0.11 12.0 0.2 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease B OB domain SWI-SNF_Ssr4 PF08549.5 EKG21244.1 - 1.4e-161 539.2 22.3 2.4e-161 538.4 15.5 1.4 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) WD40 PF00400.27 EKG21246.1 - 2.6e-27 93.6 1.9 4.8e-06 26.2 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EKG21246.1 - 0.00041 20.0 0.1 0.017 14.8 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Glyco_hydro_31 PF01055.21 EKG21247.1 - 5.3e-176 585.7 0.4 6.5e-176 585.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG21247.1 - 7.6e-11 41.7 0.7 2.3e-10 40.1 0.5 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like zf-RNPHF PF08080.7 EKG21248.1 - 0.028 13.9 0.6 0.071 12.6 0.4 1.7 1 0 0 1 1 1 0 RNPHF zinc finger PC_rep PF01851.17 EKG21249.1 - 2.9e-42 140.5 18.0 6.5e-10 38.6 0.0 9.6 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EKG21249.1 - 2.7e-17 62.8 0.2 2.2e-12 47.0 0.0 4.2 2 1 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EKG21249.1 - 3.6e-06 27.3 0.1 0.00048 20.5 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.17 EKG21249.1 - 1.5e-05 24.6 0.1 7.8 6.8 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Neur_chan_memb PF02932.11 EKG21249.1 - 5.6 6.7 8.0 5.6 6.7 2.2 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region mRNA_triPase PF02940.10 EKG21250.1 - 6.9e-51 173.0 0.1 8.4e-51 172.7 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glyco_hydro_61 PF03443.9 EKG21252.1 - 5.1e-55 186.6 0.0 5.7e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 XPG_N PF00752.12 EKG21254.1 - 1.5e-34 118.2 0.0 4.4e-34 116.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EKG21254.1 - 9.7e-25 86.4 0.2 2.6e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 XPG I-region Transposase_20 PF02371.11 EKG21254.1 - 0.00064 19.7 0.0 0.0021 18.1 0.0 1.9 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family 5_3_exonuc PF01367.15 EKG21254.1 - 0.00094 19.3 0.0 0.0029 17.8 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.15 EKG21254.1 - 0.0022 17.4 5.0 0.0022 17.4 3.4 4.0 3 0 0 3 3 3 1 Ubiquitin interaction motif SET PF00856.23 EKG21255.1 - 3e-12 47.1 0.7 2.3e-11 44.2 0.1 2.9 3 1 0 3 3 3 1 SET domain Ribosomal_S17 PF00366.15 EKG21256.1 - 7e-30 102.8 0.5 1.1e-29 102.2 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7 PF08317.6 EKG21257.1 - 2e-94 315.9 7.5 3.7e-94 315.0 5.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.1 EKG21257.1 - 1.9e-12 46.0 37.5 1.9e-12 46.0 26.0 3.3 2 1 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7_C2 PF15577.1 EKG21257.1 - 1.1e-07 31.3 0.0 2.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Spc7_C2 TBCA PF02970.11 EKG21257.1 - 0.0074 16.3 3.9 0.0074 16.3 2.7 3.6 3 1 2 5 5 5 1 Tubulin binding cofactor A Atg14 PF10186.4 EKG21257.1 - 2.1 7.2 10.4 6.6 5.5 7.2 1.8 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 EKG21257.1 - 7.7 4.2 5.7 14 3.4 3.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EKG21257.1 - 9.9 5.7 23.4 0.32 10.6 2.5 3.6 2 1 1 3 3 3 0 Mnd1 family PSI PF01437.20 EKG21259.1 - 2.2 8.5 6.3 9.2 6.5 0.5 2.5 2 0 0 2 2 2 0 Plexin repeat Asp_protease_2 PF13650.1 EKG21260.1 - 1.7e-08 34.8 0.0 3.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EKG21260.1 - 3.2e-06 26.8 0.0 8.5e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EKG21260.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.15 EKG21260.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 EKG21262.1 - 2.3e-08 33.9 1.6 2.6e-08 33.8 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein ImcF-related_N PF14331.1 EKG21262.1 - 0.016 14.1 1.2 0.021 13.7 0.9 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain Imm5 PF14423.1 EKG21262.1 - 0.017 14.7 0.1 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 Immunity protein Imm5 Erp_C PF06780.6 EKG21262.1 - 0.041 13.7 0.1 0.041 13.7 0.1 1.8 2 1 0 1 1 1 0 Erp protein C-terminus YfcL PF08891.6 EKG21262.1 - 0.11 12.5 0.2 0.45 10.5 0.0 2.2 1 1 1 2 2 2 0 YfcL protein zf-CCHC PF00098.18 EKG21263.1 - 0.0028 17.4 3.4 0.0028 17.4 2.4 2.4 2 0 0 2 2 2 1 Zinc knuckle SDA1 PF05285.7 EKG21264.1 - 4.6 6.4 8.3 5.5 6.1 5.8 1.1 1 0 0 1 1 1 0 SDA1 CTP_transf_2 PF01467.21 EKG21265.1 - 0.00017 21.6 0.0 0.0024 17.9 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase WD40 PF00400.27 EKG21266.1 - 3.8e-21 74.1 8.3 6.9e-09 35.2 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat MFS_1 PF07690.11 EKG21267.1 - 3.3e-29 101.7 32.6 3.3e-29 101.7 22.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Oleosin PF01277.12 EKG21267.1 - 0.81 9.2 15.0 0.82 9.2 1.4 2.7 2 0 0 2 2 2 0 Oleosin But2 PF09792.4 EKG21268.1 - 2e-47 160.5 0.0 2e-47 160.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain UbiA PF01040.13 EKG21269.1 - 7e-29 100.8 24.1 1.1e-28 100.2 16.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.3 EKG21269.1 - 1.5 8.9 4.2 0.91 9.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) Aminotran_3 PF00202.16 EKG21270.1 - 2.1e-78 263.5 0.0 2.5e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.3 EKG21271.1 - 8.8e-47 159.5 2.4 1.1e-46 159.1 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RGCC PF15151.1 EKG21273.1 - 0.0055 17.1 2.4 0.02 15.3 0.2 2.8 3 1 0 3 3 2 1 Response gene to complement 32 protein family Filament PF00038.16 EKG21273.1 - 0.011 15.2 3.2 0.011 15.2 2.2 3.3 2 1 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.6 EKG21273.1 - 0.019 14.7 1.5 20 5.0 0.1 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EKG21273.1 - 0.17 12.0 7.8 0.4 10.8 0.3 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family FlxA PF14282.1 EKG21273.1 - 0.22 11.4 16.0 0.08 12.8 4.4 3.7 3 2 1 4 4 4 0 FlxA-like protein AAA_13 PF13166.1 EKG21273.1 - 0.56 8.6 9.6 4.2 5.6 5.1 2.1 1 1 1 2 2 2 0 AAA domain Viral_P18 PF04521.8 EKG21273.1 - 1.8 8.0 6.8 3.6 7.0 0.7 2.7 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Baculo_PEP_C PF04513.7 EKG21273.1 - 2.7 7.8 5.8 3.2 7.5 0.1 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3373 PF11853.3 EKG21273.1 - 3.3 6.1 4.1 1.2 7.5 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) COG5 PF10392.4 EKG21273.1 - 4.2 7.3 11.8 0.19 11.6 1.8 2.9 3 1 1 4 4 4 0 Golgi transport complex subunit 5 DUF342 PF03961.8 EKG21273.1 - 5.8 5.2 6.2 2.3 6.5 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Striatin PF08232.7 EKG21273.1 - 6.2 7.1 13.9 1.7 8.9 2.6 3.3 1 1 1 2 2 2 0 Striatin family BssS PF13991.1 EKG21273.1 - 8.8 6.1 11.3 5.1 6.9 0.1 4.0 3 1 1 4 4 4 0 BssS protein family Carb_anhydrase PF00194.16 EKG21274.1 - 1.4e-17 63.5 0.2 1.1e-16 60.6 0.1 2.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase WD40 PF00400.27 EKG21275.1 - 5.2e-21 73.6 32.7 8.1e-09 35.0 0.8 10.4 10 1 0 10 10 10 7 WD domain, G-beta repeat Spt5-NGN PF03439.8 EKG21276.1 - 1.2e-22 79.4 0.0 2e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EKG21276.1 - 3.1e-18 66.1 12.1 3.1e-18 66.1 8.4 2.2 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 EKG21276.1 - 4.3e-17 62.6 74.8 1.6e-10 41.5 28.2 4.5 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EKG21276.1 - 8.4e-06 25.2 8.6 0.038 13.7 0.2 4.7 5 0 0 5 5 5 2 KOW motif PPV_E1_N PF00524.13 EKG21276.1 - 0.038 14.1 2.3 0.094 12.9 1.6 1.6 1 0 0 1 1 1 0 E1 Protein, N terminal domain DHO_dh PF01180.16 EKG21278.1 - 1.2e-65 221.3 0.0 4.2e-55 186.7 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EKG21278.1 - 0.00081 18.3 0.1 0.27 10.0 0.0 2.6 3 0 0 3 3 3 2 FMN-dependent dehydrogenase PcrB PF01884.12 EKG21278.1 - 0.0021 17.3 0.3 0.49 9.5 0.0 2.6 2 0 0 2 2 2 2 PcrB family PALP PF00291.20 EKG21279.1 - 1.1e-05 24.8 0.1 7.9e-05 22.0 0.1 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PAP2_3 PF14378.1 EKG21280.1 - 2.5e-40 138.0 11.4 4e-40 137.3 7.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 EKG21280.1 - 0.004 16.8 8.3 0.004 16.8 5.7 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EKG21280.1 - 0.0053 16.9 0.6 0.0053 16.9 0.4 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal VIT1 PF01988.14 EKG21281.1 - 9.4e-69 231.1 0.4 1.1e-68 230.9 0.3 1.0 1 0 0 1 1 1 1 VIT family Orai-1 PF07856.7 EKG21281.1 - 0.022 14.3 0.2 0.04 13.4 0.2 1.4 1 0 0 1 1 1 0 Mediator of CRAC channel activity RRN9 PF10680.4 EKG21282.1 - 1.4e-16 59.9 1.5 1.4e-16 59.9 1.1 2.4 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor AT_hook PF02178.14 EKG21282.1 - 5.4 7.0 24.9 5 7.1 6.0 3.4 2 0 0 2 2 2 0 AT hook motif DUF3198 PF11433.3 EKG21284.1 - 0.084 12.7 0.4 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) Retrotrans_gag PF03732.12 EKG21285.1 - 1.7e-06 28.0 0.5 1.7e-06 28.0 0.4 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein IL6 PF00489.12 EKG21285.1 - 0.21 11.1 1.5 0.28 10.7 0.1 1.7 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family NPV_P10 PF05531.7 EKG21286.1 - 0.042 14.0 0.0 0.048 13.8 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein LCM PF04072.9 EKG21287.1 - 5.5e-24 84.7 0.0 9.2e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase RNA_pol_Rpb5_C PF01191.14 EKG21288.1 - 2.9e-35 119.6 0.1 5.2e-35 118.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EKG21288.1 - 1.6e-28 98.9 0.0 2.5e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EKG21288.1 - 0.0029 17.3 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Restriction endonuclease DAO PF01266.19 EKG21290.1 - 2.3e-50 171.5 0.0 3.6e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG21290.1 - 2e-08 33.5 0.2 5.8e-08 31.9 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EKG21290.1 - 3.4e-08 32.9 0.1 1.9e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG21290.1 - 0.00016 21.5 0.1 0.00042 20.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG21290.1 - 0.0039 16.1 0.1 0.021 13.7 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EKG21290.1 - 0.0041 16.7 0.1 0.0086 15.7 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EKG21290.1 - 0.0098 15.8 0.2 0.039 13.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EKG21290.1 - 0.011 14.2 0.1 0.02 13.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EKG21290.1 - 0.014 15.8 0.2 0.048 14.0 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG21290.1 - 0.043 12.7 0.1 0.082 11.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2442 PF10387.4 EKG21293.1 - 0.059 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) EpuA PF11772.3 EKG21294.1 - 0.11 11.9 0.1 8 5.9 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Period_C PF12114.3 EKG21295.1 - 0.099 12.2 2.3 4.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DUF1178 PF06676.6 EKG21295.1 - 1.9 8.6 4.9 1.1 9.3 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1178) Ribosom_S12_S23 PF00164.20 EKG21296.1 - 6.1e-41 138.6 0.4 7.1e-41 138.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 KOW PF00467.24 EKG21297.1 - 7.3e-05 22.3 0.9 0.00014 21.4 0.6 1.5 1 0 0 1 1 1 1 KOW motif Ima1_N PF09779.4 EKG21298.1 - 6.2e-37 127.0 7.4 1.6e-26 93.3 0.3 2.9 3 0 0 3 3 3 2 Ima1 N-terminal domain A_amylase_inhib PF01356.14 EKG21298.1 - 0.13 12.1 0.6 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Alpha amylase inhibitor DZR PF12773.2 EKG21298.1 - 2.5 7.9 6.6 1.1 9.1 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon KH_1 PF00013.24 EKG21299.1 - 5.5e-11 41.9 0.0 8.6e-07 28.5 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EKG21299.1 - 1.1e-05 24.8 3.4 0.00049 19.6 0.1 3.1 3 0 0 3 3 3 2 KH domain ALS_ss_C PF10369.4 EKG21300.1 - 1.7e-19 69.3 0.0 7.8e-18 63.9 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase DUF1949 PF09186.6 EKG21300.1 - 0.041 13.4 0.1 0.99 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) OTCace_N PF02729.16 EKG21301.1 - 4.7e-42 143.0 0.0 7e-42 142.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EKG21301.1 - 1e-40 139.1 0.0 1.5e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LEA_2 PF03168.8 EKG21302.1 - 1.6e-08 34.8 1.1 0.8 10.1 0.0 4.6 4 0 0 4 4 4 4 Late embryogenesis abundant protein DUF3712 PF12505.3 EKG21302.1 - 1.6e-07 31.3 0.6 2.7e-06 27.4 0.3 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) DSPc PF00782.15 EKG21304.1 - 5.7e-28 97.1 0.0 8.1e-28 96.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EKG21304.1 - 0.00084 18.3 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EKG21304.1 - 0.0031 16.8 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EKG21304.1 - 0.0077 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EKG21304.1 - 0.027 14.5 0.0 0.09 12.8 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate zf-C2H2_4 PF13894.1 EKG21305.1 - 1.2e-05 25.2 20.2 0.36 11.2 1.1 4.7 3 1 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG21305.1 - 3.2e-05 23.9 18.9 0.013 15.8 0.6 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EKG21305.1 - 0.0088 16.2 0.4 0.0088 16.2 0.3 3.5 4 1 0 4 4 4 1 Zinc-finger double domain zf-CHCC PF10276.4 EKG21305.1 - 0.029 14.2 1.5 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-FCS PF06467.9 EKG21305.1 - 0.03 13.9 1.8 1.6 8.4 0.1 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_jaz PF12171.3 EKG21305.1 - 7.3 6.8 12.7 0.28 11.3 1.4 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Vfa1 PF08432.5 EKG21306.1 - 1.7e-24 86.8 20.4 2.2e-24 86.5 14.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 EKG21306.1 - 0.063 12.2 12.3 0.075 11.9 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1510 PF07423.6 EKG21306.1 - 0.063 12.6 19.7 0.07 12.4 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BTV_NS2 PF04514.7 EKG21306.1 - 0.28 10.0 14.4 0.31 9.8 10.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rtf2 PF04641.7 EKG21306.1 - 0.32 10.1 14.6 0.38 9.9 10.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger GCD14 PF08704.5 EKG21306.1 - 0.44 10.0 4.4 0.51 9.7 3.0 1.0 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit FlxA PF14282.1 EKG21306.1 - 0.61 10.0 15.1 0.82 9.6 10.5 1.2 1 0 0 1 1 1 0 FlxA-like protein FLO_LFY PF01698.11 EKG21306.1 - 0.67 8.7 15.1 0.76 8.5 10.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 EKG21306.1 - 0.68 7.8 16.3 0.75 7.7 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 EKG21306.1 - 0.9 8.0 9.9 1 7.8 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hex_IIIa PF02455.11 EKG21306.1 - 1.5 7.4 5.2 1.6 7.3 3.6 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) GAGA_bind PF06217.7 EKG21306.1 - 1.6 8.6 13.3 1.9 8.4 9.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MIP-T3 PF10243.4 EKG21306.1 - 2.1 6.7 30.0 2.5 6.4 20.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RNA_pol_3_Rpc31 PF11705.3 EKG21306.1 - 2.4 8.0 22.3 2.8 7.7 15.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF262 PF03235.9 EKG21306.1 - 2.8 7.8 8.0 3 7.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 Peptidase_S49_N PF08496.5 EKG21306.1 - 2.9 7.6 20.1 3.8 7.2 13.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ycf1 PF05758.7 EKG21306.1 - 3.1 5.3 15.4 3.3 5.3 10.7 1.0 1 0 0 1 1 1 0 Ycf1 Cytochrom_C PF00034.16 EKG21306.1 - 3.1 8.6 6.3 6.5 7.6 4.4 1.5 1 1 0 1 1 1 0 Cytochrome c Atg14 PF10186.4 EKG21306.1 - 3.4 6.5 9.3 3.7 6.3 6.5 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RR_TM4-6 PF06459.7 EKG21306.1 - 3.6 7.4 17.5 4.4 7.1 12.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2201_N PF13203.1 EKG21306.1 - 4.2 6.4 9.2 4.7 6.2 6.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Atrophin-1 PF03154.10 EKG21306.1 - 4.7 5.2 16.6 5.3 5.0 11.5 1.3 1 0 0 1 1 1 0 Atrophin-1 family Paramyxo_ncap PF00973.14 EKG21306.1 - 5.9 5.4 9.4 6.5 5.3 6.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HAUS6_N PF14661.1 EKG21306.1 - 6.4 6.0 11.6 7.1 5.9 8.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1168 PF06658.7 EKG21306.1 - 6.8 6.2 29.3 8.9 5.8 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) U79_P34 PF03064.11 EKG21306.1 - 7.1 6.0 22.4 8.4 5.8 15.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2413 PF10310.4 EKG21306.1 - 7.4 5.2 18.3 8.5 5.0 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Borrelia_P83 PF05262.6 EKG21306.1 - 8 4.6 20.1 8.9 4.4 14.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DDHD PF02862.12 EKG21306.1 - 9.7 5.9 10.3 13 5.5 7.1 1.2 1 0 0 1 1 1 0 DDHD domain Lyase_1 PF00206.15 EKG21307.1 - 2.9e-88 296.0 0.0 4.4e-88 295.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EKG21307.1 - 1.4e-27 95.5 0.1 2.4e-26 91.5 0.0 2.4 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal EGF_2 PF07974.8 EKG21308.1 - 0.00049 20.1 9.9 0.00089 19.3 6.9 1.4 1 0 0 1 1 1 1 EGF-like domain BNR_2 PF13088.1 EKG21308.1 - 0.0069 15.7 0.1 0.035 13.3 0.1 2.0 1 1 1 2 2 2 1 BNR repeat-like domain EB PF01683.13 EKG21308.1 - 0.024 14.7 5.5 0.041 13.9 3.8 1.3 1 0 0 1 1 1 0 EB module Alg14 PF08660.6 EKG21309.1 - 2.1e-41 141.7 0.0 4.2e-39 134.2 0.0 2.1 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like AAA_19 PF13245.1 EKG21309.1 - 0.073 12.8 0.8 0.47 10.2 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain Coa1 PF08695.5 EKG21310.1 - 7.8e-38 128.5 0.0 9.6e-38 128.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 MLANA PF14991.1 EKG21311.1 - 0.019 14.9 0.7 0.05 13.6 0.0 2.0 2 0 0 2 2 2 0 Protein melan-A Neurensin PF14927.1 EKG21311.1 - 0.023 14.0 0.0 0.023 14.0 0.0 3.1 3 1 0 3 3 3 0 Neurensin GKAP PF03359.8 EKG21311.1 - 2 7.9 12.0 0.37 10.3 5.1 1.8 1 1 1 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein DUF202 PF02656.10 EKG21312.1 - 9.7e-13 48.1 2.5 9.7e-13 48.1 1.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2207 PF09972.4 EKG21312.1 - 0.09 11.3 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 EKG21312.1 - 0.29 11.0 1.4 0.54 10.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4131 PF13567.1 EKG21312.1 - 2.5 7.4 6.5 2 7.7 2.7 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Tctex-1 PF03645.8 EKG21313.1 - 2.7e-34 117.0 0.0 3.2e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Abhydrolase_6 PF12697.2 EKG21314.1 - 8.1e-29 101.1 1.6 1.1e-28 100.7 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG21314.1 - 1.2e-15 57.7 0.0 1.9e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG21314.1 - 2.7e-11 43.4 0.1 8.7e-11 41.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EKG21314.1 - 1.6e-06 28.5 0.0 5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 EKG21314.1 - 0.00085 17.8 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 EKG21314.1 - 0.0041 16.7 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF411 PF04214.8 EKG21314.1 - 0.089 12.3 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF DUF362 PF04015.7 EKG21314.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) Lipase_3 PF01764.20 EKG21314.1 - 0.16 11.5 0.1 0.26 10.9 0.1 1.2 1 0 0 1 1 1 0 Lipase (class 3) Methyltransf_23 PF13489.1 EKG21315.1 - 3.4e-20 72.4 0.0 1.2e-19 70.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG21315.1 - 2.4e-09 37.7 0.0 3.9e-08 33.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG21315.1 - 3.6e-07 30.5 0.0 4.3e-06 27.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG21315.1 - 1.8e-06 28.3 0.0 5.1e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG21315.1 - 3e-06 26.8 0.0 8.3e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG21315.1 - 8.3e-05 22.8 0.0 0.00021 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKG21315.1 - 0.014 15.3 0.0 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EKG21315.1 - 0.031 14.3 0.0 0.15 12.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EKG21315.1 - 0.14 11.2 0.0 1.2 8.1 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family UbiA PF01040.13 EKG21316.1 - 7.5e-33 113.8 26.6 9.8e-33 113.4 18.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.17 EKG21317.1 - 1.2e-09 38.4 0.4 2.3e-08 34.2 0.3 2.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EKG21317.1 - 6.6e-06 26.2 7.5 6.6e-06 26.2 5.2 2.3 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EKG21317.1 - 0.0012 18.2 0.0 0.0055 16.1 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Inhibitor_I9 PF05922.11 EKG21317.1 - 0.1 13.2 1.9 0.14 12.7 0.1 2.2 2 0 0 2 2 2 0 Peptidase inhibitor I9 PHD PF00628.24 EKG21317.1 - 9.2 6.0 16.1 3.5 7.4 5.9 2.7 2 0 0 2 2 2 0 PHD-finger CN_hydrolase PF00795.17 EKG21318.1 - 1.1e-17 63.9 0.0 1.7e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.13 EKG21319.1 - 3.6e-12 45.7 0.1 7.8e-12 44.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain COG5 PF10392.4 EKG21319.1 - 0.07 13.0 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 MFS_1 PF07690.11 EKG21320.1 - 1.6e-33 115.8 26.1 1.6e-33 115.8 18.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FPN1 PF06963.7 EKG21320.1 - 0.001 17.5 0.0 0.0016 16.8 0.0 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) OATP PF03137.15 EKG21320.1 - 0.75 7.7 4.0 1.2 7.0 2.8 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SMN PF06003.7 EKG21322.1 - 3.7e-06 26.2 1.7 4.2e-05 22.7 0.3 2.2 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) MARCKS PF02063.12 EKG21322.1 - 0.018 14.9 13.7 0.022 14.6 9.5 1.1 1 0 0 1 1 1 0 MARCKS family Suf PF05843.9 EKG21322.1 - 0.19 11.4 3.2 0.22 11.2 2.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LcrG PF07216.7 EKG21322.1 - 1.6 8.8 5.0 3.1 7.8 3.4 1.6 1 1 0 1 1 1 0 LcrG protein RRM_1 PF00076.17 EKG21323.1 - 4.7e-15 54.9 0.0 1.2e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG21323.1 - 5.9e-12 45.3 0.0 1.4e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG21323.1 - 3.7e-09 36.2 0.1 7.4e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBX PF00789.15 EKG21324.1 - 8.2e-07 29.0 0.3 1.1e-05 25.3 0.0 2.6 2 1 0 2 2 2 1 UBX domain UBA PF00627.26 EKG21324.1 - 9.7e-06 25.2 0.2 3.5e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain CAF-1_p150 PF11600.3 EKG21324.1 - 0.05 12.9 37.5 0.069 12.5 26.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hydantoinase_B PF02538.9 EKG21324.1 - 0.063 11.5 1.9 0.08 11.1 1.3 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase zf-C2H2 PF00096.21 EKG21324.1 - 0.087 13.2 0.8 0.15 12.4 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type Herpes_DNAp_acc PF04929.7 EKG21324.1 - 0.13 11.1 0.0 0.13 11.1 0.0 2.2 1 1 1 2 2 2 0 Herpes DNA replication accessory factor SOBP PF15279.1 EKG21324.1 - 0.79 10.0 8.0 0.97 9.7 5.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.6 EKG21324.1 - 2.3 7.9 20.5 3.7 7.3 14.2 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 EKG21324.1 - 3.1 5.3 11.2 4.1 4.9 7.8 1.4 1 0 0 1 1 1 0 Ycf1 V_ATPase_I PF01496.14 EKG21324.1 - 9.9 3.8 10.5 12 3.5 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Motile_Sperm PF00635.21 EKG21325.1 - 3.9e-25 87.6 0.0 8.2e-25 86.5 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain T2SM PF04612.7 EKG21325.1 - 0.0063 16.3 2.8 0.014 15.2 1.9 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M Med9 PF07544.8 EKG21325.1 - 0.013 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Tmemb_cc2 PF10267.4 EKG21325.1 - 1.4 7.4 4.9 0.82 8.1 2.1 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 EKG21325.1 - 6 5.0 7.9 7.8 4.6 5.5 1.3 1 0 0 1 1 1 0 Transmembrane protein Golgin_A5 PF09787.4 EKG21325.1 - 8.9 4.6 9.2 12 4.3 6.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Asn_synthase PF00733.16 EKG21326.1 - 5.6e-70 235.7 0.0 7.5e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EKG21326.1 - 3.8e-36 123.5 0.0 6e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EKG21326.1 - 3.2e-27 95.0 0.0 5.5e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EKG21326.1 - 2.5e-07 30.1 0.0 4.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EKG21326.1 - 2.1e-05 23.3 0.0 0.00088 18.0 0.0 2.6 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EKG21326.1 - 0.0042 16.0 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD synthase QueC PF06508.8 EKG21326.1 - 0.18 11.0 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EKG21326.1 - 0.2 10.1 0.0 0.44 9.0 0.0 1.4 1 1 0 1 1 1 0 tRNA methyl transferase Abhydrolase_6 PF12697.2 EKG21327.1 - 2.2e-08 34.2 0.0 2.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG21327.1 - 9.3e-06 25.4 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EKG21327.1 - 0.002 17.9 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EKG21327.1 - 0.043 13.3 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EKG21327.1 - 0.049 12.9 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EKG21327.1 - 0.071 12.5 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pec_lyase_C PF00544.14 EKG21328.1 - 1.5e-06 27.8 0.2 2.3e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Pectate lyase p450 PF00067.17 EKG21329.1 - 6.4e-54 183.2 0.0 3.2e-39 134.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 EKG21330.1 - 4.7e-18 65.0 0.0 8.5e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EKG21331.1 - 1.3e-44 151.8 18.9 8.9e-33 113.2 9.2 2.2 1 1 1 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EKG21331.1 - 4.8e-14 51.8 0.0 1.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.22 EKG21331.1 - 2.6e-08 34.2 0.0 1.7e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 EKG21331.1 - 8.6 5.2 24.4 0.15 11.0 10.7 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 EKG21332.1 - 2.4e-22 79.1 21.1 8.6e-15 54.4 5.0 2.1 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EKG21332.1 - 7.7e-08 32.7 0.1 1.6e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EKG21332.1 - 0.0071 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF429 PF04250.8 EKG21332.1 - 0.14 11.3 0.0 0.31 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF429) GXWXG PF14231.1 EKG21334.1 - 1.7e-13 49.9 0.1 2.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 GXWXG protein p450 PF00067.17 EKG21335.1 - 4.1e-07 28.8 0.0 4.8e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Apolipoprotein PF01442.13 EKG21336.1 - 0.00085 18.8 6.7 0.0015 18.0 4.7 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Ribosomal_S30AE PF02482.14 EKG21336.1 - 0.014 15.7 4.3 0.75 10.2 0.1 2.5 1 1 1 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF445 PF04286.7 EKG21336.1 - 0.088 12.3 3.2 0.12 11.8 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Mitofilin PF09731.4 EKG21336.1 - 0.25 9.9 8.5 0.39 9.3 5.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1788 PF08747.6 EKG21336.1 - 0.32 10.8 2.0 1.1 9.1 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1788) Med11 PF10280.4 EKG21336.1 - 0.47 10.5 4.8 0.18 11.8 1.6 1.6 2 0 0 2 2 2 0 Mediator complex protein MutS_IV PF05190.13 EKG21336.1 - 0.95 9.6 7.0 0.47 10.6 0.6 2.6 2 1 1 3 3 3 0 MutS family domain IV DUF883 PF05957.8 EKG21336.1 - 2.5 8.5 6.3 11 6.4 4.4 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EKG21336.1 - 3 8.2 9.8 2.2e+02 2.3 6.8 2.5 1 1 0 1 1 1 0 YtxH-like protein ATP-synt_B PF00430.13 EKG21336.1 - 5.3 6.8 8.4 8.6 6.1 5.8 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CBM-like PF14683.1 EKG21337.1 - 2.7e-11 43.3 0.1 6.1e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EKG21337.1 - 5.6e-07 29.6 0.6 1.7e-06 28.0 0.4 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II DUF718 PF05336.8 EKG21338.1 - 1.5e-13 50.4 0.0 1.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Chitin_bind_1 PF00187.14 EKG21339.1 - 4.4e-05 23.3 17.1 4.4e-05 23.3 11.9 2.6 2 1 0 2 2 2 1 Chitin recognition protein DUF2011 PF09428.5 EKG21340.1 - 0.0052 16.6 0.1 0.0067 16.3 0.1 1.3 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) FA_desaturase PF00487.19 EKG21340.1 - 0.02 14.3 0.1 0.022 14.1 0.0 1.0 1 0 0 1 1 1 0 Fatty acid desaturase Cyclotide PF03784.8 EKG21340.1 - 0.13 12.1 0.4 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 Cyclotide family DUF1996 PF09362.5 EKG21341.1 - 3.1e-48 164.4 0.0 3.9e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) E1-E2_ATPase PF00122.15 EKG21343.1 - 5.8e-59 198.9 0.7 5.8e-59 198.9 0.5 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EKG21343.1 - 1.2e-40 139.0 9.7 1.2e-40 139.0 6.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EKG21343.1 - 1.2e-26 94.4 0.0 4.9e-26 92.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EKG21343.1 - 3.4e-15 55.7 0.0 6.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EKG21343.1 - 1.2e-11 45.1 0.0 3.5e-11 43.6 0.0 1.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EKG21343.1 - 4.3e-08 32.5 0.1 1.3e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EKG21343.1 - 0.00018 21.1 0.3 0.00093 18.8 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sulf_transp PF04143.9 EKG21344.1 - 1.2e-08 34.7 8.5 1.2e-08 34.7 5.9 2.9 3 1 0 3 3 3 1 Sulphur transport Sugar_tr PF00083.19 EKG21346.1 - 1.4e-18 66.7 7.1 4.6e-15 55.1 1.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EKG21346.1 - 0.0047 15.7 9.8 0.0063 15.2 6.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Lactamase_B PF00753.22 EKG21347.1 - 1.9e-05 24.3 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily HILPDA PF15220.1 EKG21349.1 - 0.41 10.6 5.7 4 7.4 0.2 3.0 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated Catalase PF00199.14 EKG21351.1 - 6.6e-171 568.1 0.0 7.7e-171 567.9 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EKG21351.1 - 2.5e-15 56.0 0.0 5.5e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive p450 PF00067.17 EKG21352.1 - 4.6e-07 28.7 0.0 5e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidohydro_2 PF04909.9 EKG21353.1 - 2.8e-43 148.4 0.0 3.4e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Cyclase PF04199.8 EKG21354.1 - 1.1e-15 57.7 0.0 1.7e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase DIOX_N PF14226.1 EKG21355.1 - 2.1e-23 83.0 0.2 3.9e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG21355.1 - 2.7e-20 72.5 0.0 7.3e-20 71.1 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF427 PF04248.7 EKG21356.1 - 2.2e-32 110.6 0.1 2.8e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) D-ser_dehydrat PF14031.1 EKG21357.1 - 2.9e-27 94.6 0.8 3.7e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EKG21357.1 - 6.9e-13 48.6 0.1 1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Cas_csx3 PF09620.5 EKG21359.1 - 0.038 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) VSP PF03302.8 EKG21359.1 - 1.5 7.4 5.7 0.52 8.8 1.4 1.8 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF1996 PF09362.5 EKG21360.1 - 4.9e-78 262.0 0.1 6.7e-78 261.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EKG21360.1 - 5.8e-08 32.5 2.8 2.1e-07 30.7 0.1 2.8 3 0 0 3 3 3 1 WSC domain tRNA-synt_1b PF00579.20 EKG21361.1 - 7.5e-25 87.6 0.0 9.6e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Raffinose_syn PF05691.7 EKG21362.1 - 4.3e-55 186.6 1.3 3.2e-46 157.2 0.1 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Nop14 PF04147.7 EKG21363.1 - 0.026 12.4 7.6 0.033 12.1 5.2 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EKG21363.1 - 0.3 9.0 6.8 0.4 8.6 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EKG21363.1 - 1.1 8.8 5.4 1.6 8.2 3.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nucleoplasmin PF03066.10 EKG21363.1 - 3.7 7.0 12.4 6.8 6.1 8.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin CobT PF06213.7 EKG21363.1 - 4.2 6.4 13.6 6.5 5.8 9.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 EKG21363.1 - 6.3 5.9 15.8 9.7 5.3 11.0 1.3 1 0 0 1 1 1 0 NOA36 protein DNase_NucA_NucB PF14040.1 EKG21364.1 - 1.4e-17 63.8 1.3 2.5e-17 63.0 0.9 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB Tautomerase_3 PF14832.1 EKG21365.1 - 1.5e-42 144.8 0.0 1.7e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EKG21365.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme Pescadillo_N PF06732.6 EKG21366.1 - 8.7e-115 382.8 0.1 8.7e-115 382.8 0.1 2.5 4 0 0 4 4 4 1 Pescadillo N-terminus BRCT PF00533.21 EKG21366.1 - 2.7e-08 33.8 0.0 1.5e-07 31.4 0.0 2.3 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 EKG21367.1 - 2.3e-74 250.5 28.1 2.7e-74 250.3 19.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U TP2 PF01254.13 EKG21368.1 - 0.0028 18.0 2.3 0.0035 17.6 1.6 1.1 1 0 0 1 1 1 1 Nuclear transition protein 2 p450 PF00067.17 EKG21371.1 - 8.3e-27 93.8 0.0 9.6e-27 93.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADC PF06314.6 EKG21372.1 - 1.2e-44 152.4 0.3 1.5e-44 152.0 0.2 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Fungal_trans PF04082.13 EKG21373.1 - 2.6e-13 49.4 0.5 2.6e-13 49.4 0.3 2.6 2 1 1 3 3 3 1 Fungal specific transcription factor domain COesterase PF00135.23 EKG21374.1 - 3e-61 207.7 7.5 1.1e-60 205.8 5.2 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG21374.1 - 0.00025 20.6 0.3 0.0028 17.2 0.1 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold SSP160 PF06933.6 EKG21374.1 - 0.0078 14.2 10.7 0.011 13.7 7.4 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Peptidase_S9 PF00326.16 EKG21374.1 - 0.016 14.4 0.2 0.016 14.4 0.1 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF4239 PF14023.1 EKG21375.1 - 0.19 11.1 3.7 0.28 10.5 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) MFS_1 PF07690.11 EKG21376.1 - 1.1e-20 73.7 4.1 1.2e-20 73.5 2.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21376.1 - 4.8e-07 28.7 2.7 6.2e-07 28.3 1.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EKG21376.1 - 0.0003 19.0 2.9 0.014 13.5 0.2 2.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family UPF0104 PF03706.8 EKG21376.1 - 0.0028 17.0 2.2 0.0037 16.5 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF1275 PF06912.6 EKG21376.1 - 0.0079 15.4 1.5 0.011 14.9 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF92 PF01940.11 EKG21376.1 - 0.02 14.0 3.3 0.34 10.0 0.1 2.0 1 1 1 2 2 2 0 Integral membrane protein DUF92 DUF2207 PF09972.4 EKG21376.1 - 0.028 13.0 0.3 0.033 12.7 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RCR PF12273.3 EKG21376.1 - 0.04 14.4 0.4 0.058 13.9 0.2 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red ATG22 PF11700.3 EKG21376.1 - 0.056 11.9 5.3 0.068 11.6 3.7 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like FPN1 PF06963.7 EKG21376.1 - 0.061 11.7 0.0 0.068 11.5 0.0 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2140 PF09911.4 EKG21376.1 - 0.063 12.4 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3353 PF11833.3 EKG21376.1 - 0.14 11.6 1.5 0.22 10.9 0.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) MutS_V PF00488.16 EKG21378.1 - 2e-76 256.4 0.0 3.1e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EKG21378.1 - 3.4e-50 170.6 0.0 5.7e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EKG21378.1 - 6.8e-32 109.8 0.0 1.4e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EKG21378.1 - 7.4e-14 51.6 1.0 2.4e-13 50.0 0.5 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EKG21378.1 - 4.3e-13 49.4 0.0 1.2e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain II DUF1564 PF07600.6 EKG21378.1 - 0.025 13.9 0.0 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) AAA_29 PF13555.1 EKG21378.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_6 PF12697.2 EKG21379.1 - 4.9e-33 114.9 0.2 6.3e-33 114.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG21379.1 - 3e-20 72.7 0.0 6.7e-18 65.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG21379.1 - 1.1e-16 60.9 0.0 2.4e-16 59.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG21379.1 - 4.3e-07 29.6 0.0 1.8e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EKG21379.1 - 0.00013 20.5 0.0 0.00021 19.8 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF1057 PF06342.7 EKG21379.1 - 0.00064 18.6 0.0 0.00089 18.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 EKG21379.1 - 0.00093 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EKG21379.1 - 0.011 14.7 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 EKG21379.1 - 0.051 13.0 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 EKG21379.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EKG21379.1 - 0.068 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Beta-lactamase PF00144.19 EKG21380.1 - 5.7e-40 137.3 0.0 2.6e-39 135.1 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EKG21380.1 - 0.16 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase PIG-S PF10510.4 EKG21381.1 - 6.2e-167 556.3 0.0 7.1e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Abhydrolase_6 PF12697.2 EKG21383.1 - 9.8e-34 117.2 3.2 1.2e-33 116.9 2.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG21383.1 - 9.5e-16 58.0 3.5 9.5e-16 58.0 2.4 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG21383.1 - 4.7e-15 55.5 0.1 8.9e-15 54.7 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG21383.1 - 7.4e-10 38.5 0.0 2.2e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EKG21383.1 - 3.8e-05 22.6 0.0 6.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_3 PF07859.8 EKG21383.1 - 0.012 15.1 0.1 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EKG21383.1 - 0.014 14.5 0.6 0.067 12.4 0.1 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EKG21383.1 - 0.02 13.7 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 EKG21383.1 - 0.032 13.8 0.6 0.06 12.9 0.2 1.5 2 0 0 2 2 2 0 PGAP1-like protein Esterase PF00756.15 EKG21383.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CoA_trans PF01144.18 EKG21384.1 - 2.8e-101 337.2 1.2 1.2e-61 207.6 0.2 2.2 2 0 0 2 2 2 2 Coenzyme A transferase MIP PF00230.15 EKG21384.1 - 1.9e-38 132.2 11.3 1.9e-38 132.2 7.9 1.7 2 0 0 2 2 2 1 Major intrinsic protein AcetylCoA_hyd_C PF13336.1 EKG21384.1 - 0.011 15.4 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Zn_clus PF00172.13 EKG21386.1 - 3.1e-05 23.7 9.1 6.9e-05 22.6 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EKG21386.1 - 0.0001 21.3 0.4 0.00018 20.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4243 PF14027.1 EKG21387.1 - 0.016 14.6 2.1 0.023 14.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4243) Cation_efflux PF01545.16 EKG21388.1 - 1.1e-13 50.9 0.6 6.1e-11 41.9 0.5 2.0 2 0 0 2 2 2 2 Cation efflux family BPD_transp_2 PF02653.11 EKG21388.1 - 3.7e-05 22.8 0.9 5.1e-05 22.3 0.6 1.2 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component DUF979 PF06166.7 EKG21388.1 - 0.022 13.7 1.5 0.03 13.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF979) Tic20 PF09685.5 EKG21388.1 - 0.14 12.1 1.1 0.22 11.5 0.7 1.2 1 0 0 1 1 1 0 Tic20-like protein Cation_efflux PF01545.16 EKG21389.1 - 4.3e-15 55.5 7.3 5.7e-15 55.1 5.0 1.1 1 0 0 1 1 1 1 Cation efflux family Fungal_trans PF04082.13 EKG21391.1 - 1.4e-25 89.7 2.3 1.5e-24 86.2 1.6 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.17 EKG21392.1 - 4.8e-19 68.4 0.0 7e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Dehydratase_hem PF13816.1 EKG21394.1 - 4.7e-84 282.0 0.0 5.7e-84 281.7 0.0 1.1 1 0 0 1 1 1 1 Haem-containing dehydratase Pax2_C PF12403.3 EKG21399.1 - 0.084 12.5 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Paired-box protein 2 C terminal SKG6 PF08693.5 EKG21400.1 - 3.9e-08 32.4 2.2 1.2e-07 30.9 1.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EKG21400.1 - 3.6e-06 26.6 0.1 7.7e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EKG21400.1 - 0.039 14.3 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3301 PF11743.3 EKG21400.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) SIT PF15330.1 EKG21400.1 - 1.1 9.4 3.3 1.7 8.8 0.0 2.7 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.1 EKG21400.1 - 1.1 9.0 29.1 8.1e+03 -3.6 20.2 3.2 1 1 0 1 1 1 0 TMEM154 protein family Mitofilin PF09731.4 EKG21400.1 - 5.2 5.6 8.8 6.3 5.3 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DPBB_1 PF03330.13 EKG21401.1 - 0.029 14.3 0.0 0.098 12.6 0.0 2.0 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 EKG21401.1 - 0.088 12.1 17.5 0.11 11.8 12.1 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EKG21401.1 - 6.8 6.4 9.3 8 6.2 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.5 EKG21404.1 - 0.12 11.9 7.7 0.14 11.7 5.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AMP-binding PF00501.23 EKG21405.1 - 2.7e-88 296.1 0.0 3.4e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EKG21405.1 - 1.6e-14 54.5 0.1 5.7e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EKG21405.1 - 0.00075 18.1 0.0 0.0071 14.9 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Flag1_repress PF03614.8 EKG21405.1 - 0.081 12.4 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Repressor of phase-1 flagellin RTX_C PF08339.5 EKG21405.1 - 0.18 11.4 0.4 2.1 8.0 0.1 2.5 1 1 1 2 2 2 0 RTX C-terminal domain G-patch PF01585.18 EKG21406.1 - 1.8e-10 40.4 3.3 3.6e-10 39.4 2.3 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 EKG21406.1 - 0.0026 17.3 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG21406.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPT6_acidic PF14632.1 EKG21406.1 - 0.017 15.2 1.0 0.017 15.2 0.7 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 RRM_6 PF14259.1 EKG21406.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FA_desaturase PF00487.19 EKG21407.1 - 1.3e-12 47.7 7.3 1.6e-12 47.4 5.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase YCII PF03795.9 EKG21408.1 - 0.0042 17.2 0.0 0.0053 16.9 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Peptidase_M24 PF00557.19 EKG21409.1 - 4.7e-12 45.9 0.0 5.8e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.14 EKG21409.1 - 0.00035 19.2 0.0 0.00049 18.7 0.0 1.1 1 0 0 1 1 1 1 Pectinesterase GTP_EFTU_D3 PF03143.12 EKG21409.1 - 0.048 13.8 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu C-terminal domain Peptidase_M24 PF00557.19 EKG21410.1 - 3.7e-28 98.5 0.0 4.4e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.26 EKG21411.1 - 1.1e-20 73.1 0.3 1.6e-20 72.5 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 EKG21412.1 - 8.1e-61 205.7 7.0 9.1e-61 205.5 4.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin TonB_dep_Rec PF00593.19 EKG21412.1 - 0.023 14.6 5.4 0.029 14.2 3.8 1.2 1 0 0 1 1 1 0 TonB dependent receptor PPI_Ypi1 PF07491.6 EKG21413.1 - 8.4e-26 89.3 6.9 2.9e-25 87.6 4.8 1.9 1 1 0 1 1 1 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 EKG21413.1 - 0.062 11.6 11.7 0.071 11.4 8.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 EKG21413.1 - 0.63 8.0 8.5 0.74 7.7 5.9 1.0 1 0 0 1 1 1 0 CDC45-like protein CRM1_C PF08767.6 EKG21414.1 - 3.1e-131 437.0 0.9 3.1e-131 437.0 0.6 3.2 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EKG21414.1 - 1.4e-38 132.1 4.2 1.4e-38 132.1 2.9 3.5 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EKG21414.1 - 2.9e-12 46.3 0.1 1.1e-11 44.4 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 EKG21414.1 - 0.012 15.8 1.9 5.8 7.2 0.1 4.0 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Ank_2 PF12796.2 EKG21415.1 - 1.5e-36 124.5 5.2 9.4e-13 48.3 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EKG21415.1 - 1.7e-27 93.8 11.8 6.3e-06 25.7 0.0 8.4 7 1 1 8 8 8 6 Ankyrin repeat SPX PF03105.14 EKG21415.1 - 2.8e-27 96.2 14.6 2.6e-14 53.6 4.1 2.4 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 EKG21415.1 - 2.2e-25 88.5 2.5 1.9e-08 34.6 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EKG21415.1 - 2.6e-17 62.4 11.4 3.1e-05 24.0 0.0 7.0 3 1 5 8 8 8 6 Ankyrin repeats (many copies) GDPD PF03009.12 EKG21415.1 - 8.8e-13 48.3 0.0 2.8e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_3 PF13606.1 EKG21415.1 - 1e-11 43.8 11.3 0.017 15.3 0.0 7.7 9 0 0 9 9 9 3 Ankyrin repeat SOG2 PF10428.4 EKG21416.1 - 8.6e-32 110.3 1.1 8.6e-32 110.3 0.8 2.3 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EKG21416.1 - 6.4e-15 54.3 3.0 1.7e-08 33.8 0.7 3.6 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EKG21416.1 - 5.1e-14 51.7 1.2 8.3e-09 35.0 0.1 3.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EKG21416.1 - 1.1e-07 30.8 3.5 0.24 11.5 0.0 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EKG21416.1 - 2.1e-05 23.9 0.2 40 5.0 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat Snf7 PF03357.16 EKG21416.1 - 0.012 14.9 1.5 0.04 13.3 0.8 2.0 2 0 0 2 2 2 0 Snf7 LRR_6 PF13516.1 EKG21416.1 - 0.16 12.1 0.2 12 6.3 0.0 3.7 3 1 1 4 4 4 0 Leucine Rich repeat DUF647 PF04884.9 EKG21418.1 - 9.2e-09 34.8 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis ELFV_dehydrog PF00208.16 EKG21418.1 - 0.038 13.5 0.0 0.043 13.3 0.0 1.0 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RGS PF00615.14 EKG21420.1 - 1.7e-12 47.4 0.0 3.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain 4HBT PF03061.17 EKG21422.1 - 0.00026 21.0 0.4 0.059 13.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily MHYT PF03707.11 EKG21424.1 - 1.6e-17 63.3 7.1 4.3e-07 29.9 0.0 4.5 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat TauE PF01925.14 EKG21424.1 - 2.3e-07 30.5 12.0 2.3e-07 30.5 8.3 2.4 2 1 1 3 3 3 1 Sulfite exporter TauE/SafE ABC2_membrane_5 PF13346.1 EKG21424.1 - 0.00044 19.6 1.6 0.00094 18.5 1.1 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4448 PF14610.1 EKG21424.1 - 0.047 13.1 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) HAMP PF00672.20 EKG21424.1 - 0.31 11.2 4.9 0.28 11.4 0.2 3.1 2 0 0 2 2 2 0 HAMP domain DUF165 PF02592.10 EKG21424.1 - 0.39 10.8 11.9 1.3 9.2 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 DUF2157 PF09925.4 EKG21424.1 - 8.9 5.9 13.8 12 5.4 3.4 2.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Abhydrolase_9_N PF15420.1 EKG21424.1 - 9.4 5.9 11.1 2.9 7.6 4.2 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus CopD PF05425.8 EKG21424.1 - 9.5 6.4 15.1 3.5 7.8 0.2 3.1 3 0 0 3 3 3 0 Copper resistance protein D WD40 PF00400.27 EKG21425.1 - 3.8e-31 105.8 0.4 3.6e-09 36.1 0.0 4.6 4 1 0 4 4 4 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EKG21425.1 - 1.5e-05 24.3 0.0 0.097 12.1 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PIN_2 PF10130.4 EKG21425.1 - 0.065 13.2 1.5 0.16 11.9 0.5 1.8 1 1 0 2 2 2 0 PIN domain Nucleoporin_N PF08801.6 EKG21425.1 - 0.12 11.0 0.1 0.37 9.4 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like FMN_dh PF01070.13 EKG21426.1 - 2.9e-109 365.2 0.0 3.3e-109 365.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EKG21426.1 - 0.0005 19.0 0.4 0.00082 18.3 0.3 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EKG21426.1 - 0.0016 17.7 0.3 0.4 9.9 0.0 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 EKG21426.1 - 0.018 14.1 0.4 2.7 6.9 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EKG21426.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase PP2C PF00481.16 EKG21427.1 - 5.5e-81 271.7 0.0 8.3e-81 271.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKG21427.1 - 0.00073 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C EGF_3 PF12947.2 EKG21428.1 - 0.19 11.7 3.1 0.55 10.2 2.2 1.8 1 1 0 1 1 1 0 EGF domain CTP_transf_2 PF01467.21 EKG21429.1 - 2.3e-20 73.2 0.0 3.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase Sporozoite_P67 PF05642.6 EKG21429.1 - 3.2 5.5 7.6 5 4.8 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 EKG21429.1 - 3.2 5.6 5.6 6 4.7 3.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.2 EKG21432.1 - 7.4e-15 55.0 0.6 4.8e-06 26.8 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EKG21432.1 - 1.7e-12 46.5 0.1 9.7e-06 25.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EKG21432.1 - 4.3e-10 39.4 0.7 4.1e-05 23.6 0.0 4.2 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG21432.1 - 2.2e-08 33.5 0.4 0.11 12.8 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EKG21432.1 - 8.7e-05 22.9 0.6 0.058 13.9 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Pex19 PF04614.7 EKG21436.1 - 1.4e-71 241.0 9.8 2.3e-71 240.3 6.8 1.3 1 0 0 1 1 1 1 Pex19 protein family Pup PF05639.6 EKG21436.1 - 3.5 8.1 7.7 17 5.9 1.5 2.9 2 0 0 2 2 2 0 Pup-like protein UQ_con PF00179.21 EKG21438.1 - 4.1e-48 162.3 0.0 4.8e-48 162.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG21438.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKG21438.1 - 0.0047 16.8 1.3 0.0091 15.8 0.9 1.8 1 1 0 1 1 1 1 RWD domain HEAT PF02985.17 EKG21439.1 - 1.8e-10 39.9 2.9 0.094 12.8 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.20 EKG21439.1 - 3e-10 39.7 0.0 5e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21439.1 - 8.5e-07 28.2 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 EKG21439.1 - 0.00016 22.0 1.4 1.3 9.5 0.4 3.7 3 1 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 EKG21439.1 - 0.00028 21.1 1.7 0.099 12.9 0.1 3.7 2 1 2 4 4 4 2 HEAT repeats Kinase-like PF14531.1 EKG21439.1 - 0.0093 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.2 EKG21439.1 - 0.033 14.0 0.0 0.24 11.2 0.0 2.1 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EKG21439.1 - 0.062 11.6 0.0 0.15 10.3 0.0 1.6 1 1 1 2 2 2 0 Adaptin N terminal region GCC2_GCC3 PF07699.8 EKG21440.1 - 0.0059 16.1 1.4 0.011 15.2 1.0 1.4 1 0 0 1 1 1 1 GCC2 and GCC3 AvrE PF11725.3 EKG21440.1 - 1.6 5.6 8.3 2.6 4.9 5.7 1.2 1 0 0 1 1 1 0 Pathogenicity factor Ndc1_Nup PF09531.5 EKG21442.1 - 9.5e-104 347.9 0.0 1.1e-103 347.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Sec8_exocyst PF04048.9 EKG21442.1 - 0.069 12.7 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Syntaxin_2 PF14523.1 EKG21443.1 - 1e-24 86.4 6.6 1.7e-24 85.8 0.4 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EKG21443.1 - 1.5e-18 66.1 2.9 1.5e-18 66.1 2.0 2.1 3 0 0 3 3 3 1 SNARE domain Synaptobrevin PF00957.16 EKG21443.1 - 0.003 17.1 0.1 0.0095 15.5 0.0 1.9 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.16 EKG21443.1 - 0.011 15.2 6.0 0.025 14.1 2.3 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 EKG21443.1 - 0.011 15.4 2.1 2.9 7.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PMC2NT PF08066.7 EKG21443.1 - 0.053 13.8 0.2 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 PMC2NT (NUC016) domain SlyX PF04102.7 EKG21443.1 - 4.4 7.7 9.8 6.8 7.1 0.1 3.4 2 2 2 4 4 4 0 SlyX RRM_1 PF00076.17 EKG21444.1 - 3.6e-16 58.5 0.0 6.1e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG21444.1 - 1.8e-13 50.2 0.0 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG21444.1 - 0.00017 21.3 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EKG21444.1 - 0.0013 16.6 0.2 0.0016 16.4 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EKG21444.1 - 0.011 16.0 1.2 0.017 15.3 0.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EMP24_GP25L PF01105.19 EKG21444.1 - 0.039 13.6 1.3 0.053 13.2 0.9 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD APG6 PF04111.7 EKG21444.1 - 0.051 12.6 1.5 0.056 12.4 1.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 STAT_alpha PF01017.15 EKG21444.1 - 0.056 13.1 2.0 0.078 12.6 1.4 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain HAP1_N PF04849.8 EKG21444.1 - 0.078 11.9 4.9 0.11 11.4 3.4 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region IncA PF04156.9 EKG21444.1 - 0.083 12.4 1.0 0.1 12.1 0.7 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EKG21444.1 - 0.22 11.8 4.9 0.35 11.1 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Spc24 PF08286.6 EKG21444.1 - 1.1 8.9 5.3 1.6 8.4 3.7 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EKG21444.1 - 1.4 8.4 5.0 2 7.9 3.5 1.3 1 0 0 1 1 1 0 Septum formation initiator GRP PF07172.6 EKG21444.1 - 3.7 8.0 16.5 11 6.5 11.4 1.8 1 0 0 1 1 1 0 Glycine rich protein family Ion_trans PF00520.26 EKG21445.1 - 5e-10 38.9 3.4 2.4e-09 36.7 1.5 1.9 2 0 0 2 2 2 1 Ion transport protein bZIP_1 PF00170.16 EKG21445.1 - 0.00019 21.3 2.4 0.00028 20.7 1.7 1.3 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.10 EKG21445.1 - 0.0021 17.5 0.5 0.0032 16.9 0.3 1.3 1 0 0 1 1 1 1 Septum formation initiator bZIP_2 PF07716.10 EKG21445.1 - 0.0028 17.4 2.6 0.0044 16.8 1.8 1.2 1 0 0 1 1 1 1 Basic region leucine zipper Frigida PF07899.6 EKG21445.1 - 0.0036 16.1 0.5 0.0057 15.4 0.4 1.3 1 0 0 1 1 1 1 Frigida-like protein PKD_channel PF08016.7 EKG21445.1 - 0.0079 14.6 2.4 0.012 14.0 1.6 1.4 1 1 0 1 1 1 1 Polycystin cation channel DUF3333 PF11812.3 EKG21445.1 - 0.011 15.7 0.2 0.23 11.4 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Nnf1 PF03980.9 EKG21445.1 - 0.028 14.3 0.6 0.043 13.8 0.4 1.2 1 0 0 1 1 1 0 Nnf1 ADIP PF11559.3 EKG21445.1 - 0.031 14.1 0.5 0.043 13.7 0.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 EKG21445.1 - 0.05 13.3 2.1 0.11 12.2 1.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 EKG21445.1 - 0.15 11.8 0.5 0.24 11.1 0.3 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.13 EKG21445.1 - 0.16 11.9 1.9 0.26 11.2 1.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Methyltransf_16 PF10294.4 EKG21447.1 - 9.4e-21 74.0 0.0 1.2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Gag_p30 PF02093.11 EKG21448.1 - 0.014 14.6 0.1 0.029 13.5 0.1 1.5 1 0 0 1 1 1 0 Gag P30 core shell protein Myb_DNA-binding PF00249.26 EKG21448.1 - 0.09 12.8 0.4 0.27 11.3 0.2 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Anp1 PF03452.9 EKG21449.1 - 3.5e-109 364.1 0.2 4.2e-109 363.8 0.1 1.1 1 0 0 1 1 1 1 Anp1 CotE PF10628.4 EKG21449.1 - 0.062 12.6 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Outer spore coat protein E (CotE) Snf7 PF03357.16 EKG21450.1 - 0.015 14.7 0.8 0.015 14.7 0.5 2.3 2 1 0 2 2 2 0 Snf7 Ecm33 PF12454.3 EKG21451.1 - 7.3e-10 38.5 7.7 2e-09 37.1 5.3 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EKG21451.1 - 1.1e-07 31.7 0.4 0.15 12.0 0.0 4.1 2 2 2 5 5 5 2 Receptor L domain HhH-GPD PF00730.20 EKG21452.1 - 1.1e-11 44.9 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AT_hook PF02178.14 EKG21452.1 - 0.0035 16.8 0.7 0.021 14.4 0.5 2.5 1 0 0 1 1 1 1 AT hook motif DUF977 PF06163.6 EKG21452.1 - 0.042 13.5 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) UCR_14kD PF02271.11 EKG21453.1 - 7.9e-45 150.9 0.0 9.1e-45 150.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EKG21454.1 - 1.3e-68 226.7 0.1 2.9e-23 81.3 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein CENP-Q PF13094.1 EKG21456.1 - 0.049 13.6 0.6 0.049 13.6 0.4 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1459 PF07312.6 EKG21456.1 - 1.1 9.2 6.2 2.5 8.1 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) DUF1427 PF07235.6 EKG21457.1 - 0.011 15.7 0.2 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) tRNA-synt_1g PF09334.6 EKG21459.1 - 1.1e-136 455.6 1.5 2.6e-75 253.5 0.4 2.2 1 1 1 2 2 2 2 tRNA synthetases class I (M) Laminin_EGF PF00053.19 EKG21459.1 - 0.088 12.7 2.1 0.19 11.6 1.4 1.5 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Aconitase PF00330.15 EKG21460.1 - 2.3e-143 478.0 0.0 1.3e-142 475.5 0.0 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EKG21460.1 - 1e-38 132.4 0.0 1.6e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain PHP PF02811.14 EKG21460.1 - 0.063 13.0 0.0 0.79 9.4 0.0 2.4 2 1 1 3 3 3 0 PHP domain peroxidase PF00141.18 EKG21461.1 - 5.4e-51 173.2 0.0 8.5e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Sporozoite_P67 PF05642.6 EKG21462.1 - 1.4 6.6 15.7 1.6 6.4 10.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BASP1 PF05466.7 EKG21462.1 - 1.5 8.6 26.1 1.8 8.2 18.1 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DUF4643 PF15485.1 EKG21462.1 - 4.2 6.7 9.4 4.7 6.5 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Macoilin PF09726.4 EKG21462.1 - 8 4.6 15.4 9.8 4.3 10.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Yae1_N PF09811.4 EKG21463.1 - 2.9e-09 36.3 1.2 2.9e-09 36.3 0.8 2.2 2 0 0 2 2 2 1 Essential protein Yae1, N terminal zinc_ribbon_6 PF14599.1 EKG21464.1 - 1.4e-22 79.2 1.3 1.4e-22 79.2 0.9 4.6 4 2 2 6 6 3 1 Zinc-ribbon zf-CHY PF05495.7 EKG21464.1 - 2.8e-15 56.2 21.4 2.8e-15 56.2 14.8 4.3 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EKG21464.1 - 3.2e-11 42.8 4.8 3.2e-11 42.8 3.4 4.3 3 1 1 4 4 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EKG21464.1 - 1.2e-07 31.5 5.9 1.2e-07 31.5 4.1 5.8 3 1 2 5 5 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG21464.1 - 1.4e-07 31.0 6.3 1.4e-07 31.0 4.4 5.4 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG21464.1 - 2.2e-05 24.0 8.0 2.2e-05 24.0 5.6 6.7 4 2 1 5 5 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EKG21464.1 - 0.0039 17.0 6.4 0.0039 17.0 4.4 4.8 4 1 2 6 6 3 1 zinc finger of C3HC4-type, RING Daxx PF03344.10 EKG21464.1 - 0.015 13.8 11.3 0.027 12.9 7.8 1.3 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 EKG21464.1 - 0.61 9.5 13.0 1.2 8.5 9.0 1.5 1 0 0 1 1 1 0 Nucleoplasmin Cwf_Cwc_15 PF04889.7 EKG21464.1 - 2 8.0 11.5 4.3 6.9 8.0 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 EKG21464.1 - 5.1 4.8 14.7 7.5 4.3 10.2 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L31e PF01198.14 EKG21465.1 - 3.9e-38 128.9 1.3 4.9e-38 128.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MS_channel PF00924.13 EKG21465.1 - 0.12 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel Sld5 PF05916.6 EKG21466.1 - 1.6e-25 89.4 0.0 2.3e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Ribosomal_L17 PF01196.14 EKG21467.1 - 7.7e-31 106.5 0.0 1.6e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 DUF2312 PF10073.4 EKG21467.1 - 0.035 13.4 0.2 0.11 11.8 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Helicase_C PF00271.26 EKG21469.1 - 3.8e-17 61.8 0.0 9.2e-14 51.0 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EKG21469.1 - 1.4e-16 60.4 0.0 2.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PPR_2 PF13041.1 EKG21470.1 - 1.3e-14 53.9 0.3 7.7e-05 22.5 0.0 5.0 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 EKG21470.1 - 1.8e-14 52.7 0.7 0.0014 18.7 0.0 5.3 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 EKG21470.1 - 1.1e-12 46.9 0.6 0.0015 18.4 0.1 5.4 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.2 EKG21470.1 - 1.3e-06 27.7 0.4 0.57 9.7 0.0 4.9 5 0 0 5 5 5 3 PPR repeat MRP-S25 PF13741.1 EKG21471.1 - 2.1e-69 233.5 12.9 1.3e-67 227.6 8.9 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EKG21471.1 - 0.13 12.1 5.1 0.48 10.3 3.2 2.2 1 1 0 1 1 1 0 Mitochondrial ribosomal protein S23 TatD_DNase PF01026.16 EKG21472.1 - 1.8e-52 178.1 0.0 2e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase zf-C2H2_4 PF13894.1 EKG21473.1 - 0.0061 16.8 4.3 0.52 10.7 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EKG21473.1 - 0.027 14.5 0.7 0.75 9.9 0.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MFS_1 PF07690.11 EKG21474.1 - 7.3e-38 130.1 25.5 7.3e-38 130.1 17.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily EcsB PF05975.7 EKG21474.1 - 0.00096 17.7 0.1 0.00096 17.7 0.1 1.9 3 0 0 3 3 3 1 Bacterial ABC transporter protein EcsB MNSV_P7B PF06692.6 EKG21474.1 - 0.059 13.1 0.3 0.78 9.5 0.1 2.5 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein DUF1129 PF06570.6 EKG21474.1 - 9.1 5.5 9.9 3.3 6.9 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF1857 PF08982.6 EKG21475.1 - 1.7e-17 63.3 0.0 2.1e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) DUF2414 PF10309.4 EKG21476.1 - 1.7e-20 72.4 0.1 3.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Big_3_3 PF13750.1 EKG21476.1 - 0.12 11.7 0.1 0.22 10.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Nop14 PF04147.7 EKG21477.1 - 0.47 8.3 15.7 0.71 7.7 10.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EKG21477.1 - 1.9 6.4 6.4 2.8 5.8 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec23_trunk PF04811.10 EKG21478.1 - 5.3e-81 271.5 0.0 7.5e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EKG21478.1 - 2.5e-34 116.7 0.2 5.2e-34 115.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EKG21478.1 - 1.3e-30 105.7 0.1 3.1e-30 104.5 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EKG21478.1 - 6.1e-17 60.8 6.0 1.2e-16 59.9 4.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EKG21478.1 - 2.1e-12 46.5 0.0 5.8e-12 45.1 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Pkinase PF00069.20 EKG21479.1 - 3e-24 85.5 0.0 4.8e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21479.1 - 1.7e-15 56.7 0.0 3.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG21479.1 - 0.03 13.2 0.0 0.072 12.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like DIE2_ALG10 PF04922.7 EKG21481.1 - 1.3e-76 258.0 21.0 4.9e-69 233.1 11.4 2.8 2 1 0 2 2 2 2 DIE2/ALG10 family Steroid_dh PF02544.11 EKG21483.1 - 9.2e-17 61.1 1.8 7.1e-16 58.3 0.0 2.6 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3520 PF12034.3 EKG21484.1 - 0.11 12.5 0.1 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3520) CTP_transf_2 PF01467.21 EKG21485.1 - 3.6e-08 33.6 0.0 3.1e-05 24.0 0.0 2.7 2 1 0 2 2 2 2 Cytidylyltransferase FMN_dh PF01070.13 EKG21486.1 - 6.4e-112 373.9 0.0 8.1e-112 373.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EKG21486.1 - 8.1e-05 21.6 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EKG21486.1 - 0.00054 19.2 0.3 0.013 14.7 0.2 2.1 1 1 1 2 2 2 1 Nitronate monooxygenase IMPDH PF00478.20 EKG21486.1 - 0.0025 16.7 0.1 0.046 12.6 0.1 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Cut8_N PF14482.1 EKG21487.1 - 0.55 10.2 5.7 4.8 7.2 0.6 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain MCLC PF05934.6 EKG21487.1 - 1.6 6.9 5.7 2.1 6.5 3.9 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) adh_short_C2 PF13561.1 EKG21488.1 - 1e-12 48.3 0.0 1.2e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG21488.1 - 0.00056 19.8 0.1 0.0057 16.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase HET PF06985.6 EKG21489.1 - 1.2e-24 87.0 0.0 3.8e-24 85.4 0.0 2.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ACOX PF01756.14 EKG21490.1 - 2.8e-39 134.4 0.7 7.8e-39 132.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EKG21490.1 - 1.4e-25 89.9 0.6 3.8e-25 88.5 0.4 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EKG21490.1 - 4.1e-10 39.0 0.1 4.1e-10 39.0 0.0 2.7 3 1 1 4 4 4 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EKG21490.1 - 9.1e-08 32.3 0.2 0.0023 18.0 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain TES PF08034.6 EKG21492.1 - 0.0026 17.7 0.6 84 3.3 0.0 5.5 1 1 7 8 8 8 0 Trematode eggshell synthesis protein CaM-KIIN PF15170.1 EKG21492.1 - 0.14 12.1 9.7 2.8 7.9 0.1 4.3 1 1 3 5 5 5 0 Calcium/calmodulin-dependent protein kinase II inhibitor Ribosomal_L29 PF00831.18 EKG21492.1 - 5.2 6.8 7.9 55 3.5 0.1 5.0 3 2 2 5 5 5 0 Ribosomal L29 protein HET PF06985.6 EKG21494.1 - 1.3e-22 80.4 0.0 2.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EKG21495.1 - 1.1e-17 64.5 0.2 2.5e-17 63.3 0.2 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mito_carr PF00153.22 EKG21496.1 - 5.9e-46 154.1 8.8 3e-18 65.3 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Form-deh_trans PF09163.6 EKG21496.1 - 0.47 9.9 1.9 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Ribonuc_L-PSP PF01042.16 EKG21497.1 - 1.1e-08 34.7 0.0 1.2e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP K_trans PF02705.11 EKG21498.1 - 1.4e-178 594.5 12.1 1.7e-178 594.3 8.4 1.0 1 0 0 1 1 1 1 K+ potassium transporter Collar PF07484.7 EKG21498.1 - 0.06 13.1 0.3 12 5.7 0.0 2.7 2 0 0 2 2 2 0 Phage Tail Collar Domain IncA PF04156.9 EKG21500.1 - 8.4 5.9 17.2 1.3 8.6 0.8 2.2 2 0 0 2 2 2 0 IncA protein AhpC-TSA PF00578.16 EKG21501.1 - 0.009 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EKG21501.1 - 0.073 12.6 0.7 0.13 11.8 0.4 1.6 1 1 0 1 1 1 0 Redoxin PPE PF00823.14 EKG21501.1 - 0.16 11.8 4.9 0.23 11.2 3.4 1.2 1 0 0 1 1 1 0 PPE family HSP9_HSP12 PF04119.7 EKG21501.1 - 0.88 9.7 5.4 0.38 10.8 1.6 1.9 2 1 0 2 2 2 0 Heat shock protein 9/12 Aa_trans PF01490.13 EKG21502.1 - 7.6e-42 143.2 29.1 9.5e-42 142.9 20.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EKG21502.1 - 4.9e-05 22.3 18.3 9.4e-05 21.3 12.7 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Pectate_lyase PF03211.8 EKG21504.1 - 1.1e-61 207.9 1.2 1.4e-61 207.6 0.8 1.0 1 0 0 1 1 1 1 Pectate lyase Rib_5-P_isom_A PF06026.9 EKG21504.1 - 0.096 11.9 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Lactamase_B_2 PF12706.2 EKG21506.1 - 2.2e-05 24.0 0.1 2.7e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EKG21506.1 - 0.0015 18.2 0.0 0.0017 18.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CRAL_TRIO_2 PF13716.1 EKG21508.1 - 2.4e-33 115.1 0.0 3.5e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EKG21508.1 - 4.2e-22 78.3 0.0 9.2e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EKG21508.1 - 3.3e-05 23.4 0.0 6.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Tcf25 PF04910.9 EKG21509.1 - 5.1e-78 262.5 0.0 8.3e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 BUD22 PF09073.5 EKG21509.1 - 0.26 10.3 28.9 0.42 9.6 20.0 1.2 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.6 EKG21509.1 - 0.27 10.1 21.5 0.51 9.2 14.9 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 EKG21509.1 - 0.95 7.2 23.8 1.5 6.6 16.5 1.2 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 EKG21509.1 - 1.9 8.1 6.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Glypican PF01153.14 EKG21509.1 - 2.3 6.7 6.4 3.8 6.0 4.5 1.3 1 0 0 1 1 1 0 Glypican SDA1 PF05285.7 EKG21509.1 - 3.7 6.7 25.5 0.82 8.8 15.4 1.5 2 0 0 2 2 2 0 SDA1 YqfQ PF14181.1 EKG21509.1 - 9.6 6.2 15.0 1.1 9.3 6.3 2.3 1 1 1 2 2 2 0 YqfQ-like protein PP2C PF00481.16 EKG21510.1 - 4.6e-38 131.0 0.0 8.9e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EKG21510.1 - 0.00093 18.6 0.1 0.0032 16.9 0.0 2.0 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EKG21510.1 - 0.015 15.0 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Sedlin_N PF04628.8 EKG21511.1 - 3.4e-26 91.6 0.0 4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EKG21511.1 - 0.043 13.5 0.0 0.52 10.0 0.0 2.0 1 1 0 1 1 1 0 Sybindin-like family Oxidored_q6 PF01058.17 EKG21512.1 - 5.5e-22 77.7 0.0 7.7e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit bZIP_2 PF07716.10 EKG21515.1 - 7.5e-13 48.0 12.1 1.6e-12 46.9 8.4 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EKG21515.1 - 4.2e-05 23.4 12.2 0.00018 21.3 8.4 2.0 1 1 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 EKG21515.1 - 0.0056 16.4 0.5 0.0056 16.4 0.3 2.2 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein bZIP_Maf PF03131.12 EKG21515.1 - 0.0071 16.6 3.9 0.019 15.2 2.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor XhlA PF10779.4 EKG21515.1 - 0.0088 15.9 3.0 0.0088 15.9 2.1 1.8 2 0 0 2 2 2 1 Haemolysin XhlA Syntaxin PF00804.20 EKG21515.1 - 0.044 13.9 4.3 0.1 12.7 3.0 1.7 1 0 0 1 1 1 0 Syntaxin Ribosomal_S2 PF00318.15 EKG21515.1 - 0.046 12.9 1.0 0.07 12.3 0.7 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 TSC22 PF01166.13 EKG21515.1 - 0.047 13.6 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family V_ATPase_I PF01496.14 EKG21515.1 - 3.2 5.4 5.4 4.2 5.0 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EKG21515.1 - 4.7 7.6 7.9 4.3 7.7 4.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CENP-N PF05238.8 EKG21516.1 - 2.3e-114 382.5 0.0 2.6e-114 382.3 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DASH_Dad2 PF08654.5 EKG21517.1 - 1.8e-35 120.9 3.0 2.2e-35 120.7 2.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Chordopox_A30L PF06015.7 EKG21517.1 - 0.0081 15.7 0.2 0.016 14.7 0.1 1.6 1 1 1 2 2 2 1 Chordopoxvirus A30L protein Seryl_tRNA_N PF02403.17 EKG21517.1 - 0.57 10.2 5.4 0.18 11.8 0.9 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Shugoshin_N PF07558.6 EKG21518.1 - 1e-12 47.5 7.2 1e-12 47.5 5.0 1.9 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EKG21518.1 - 8.6e-11 41.1 2.5 8.6e-11 41.1 1.7 3.5 4 0 0 4 4 4 1 Shugoshin C terminus Ras PF00071.17 EKG21519.1 - 3.6e-56 189.0 0.0 4.2e-56 188.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG21519.1 - 8.6e-16 58.5 0.0 1.4e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG21519.1 - 1.6e-07 30.7 0.0 2.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EKG21519.1 - 0.00099 18.3 0.0 0.0019 17.4 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EKG21519.1 - 0.001 18.5 0.1 0.0045 16.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EKG21519.1 - 0.022 13.8 0.0 0.03 13.4 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EKG21519.1 - 0.065 12.7 0.0 11 5.5 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ufd2P_core PF10408.4 EKG21520.1 - 1.1e-51 175.9 0.3 1.4e-51 175.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core T2SM PF04612.7 EKG21520.1 - 0.077 12.7 0.1 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Ufd2P_core PF10408.4 EKG21521.1 - 2.7e-134 448.7 1.4 3.1e-134 448.5 1.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EKG21521.1 - 1.4e-28 98.5 1.3 1.4e-28 98.5 0.9 1.9 2 0 0 2 2 2 1 U-box domain DUF1977 PF09320.6 EKG21522.1 - 5.3e-25 87.7 0.0 8.6e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EKG21522.1 - 1.7e-23 82.0 0.8 2.8e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3536 PF12055.3 EKG21522.1 - 0.12 11.4 0.1 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) DUF3533 PF12051.3 EKG21523.1 - 1e-84 284.5 18.6 1.2e-84 284.3 12.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Gal_mutarotas_2 PF13802.1 EKG21523.1 - 0.18 11.7 0.6 16 5.4 0.0 2.9 2 1 1 3 3 3 0 Galactose mutarotase-like Glyco_transf_28 PF03033.15 EKG21524.1 - 2.6e-21 75.8 0.0 4.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EKG21524.1 - 1e-06 27.6 0.1 1.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EKG21524.1 - 0.00018 21.2 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EKG21524.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF2985 PF11204.3 EKG21525.1 - 4.3e-35 119.3 0.4 4.3e-35 119.3 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) GHMP_kinases_N PF00288.21 EKG21526.1 - 2.3e-11 43.5 0.4 6.2e-11 42.2 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EKG21526.1 - 0.013 15.7 0.0 0.072 13.2 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal ThiS PF02597.15 EKG21526.1 - 0.13 12.6 0.2 21 5.6 0.0 2.4 2 0 0 2 2 2 0 ThiS family Mur_ligase_M PF08245.7 EKG21527.1 - 1.4e-05 25.2 0.0 2.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EKG21527.1 - 0.0034 17.3 0.0 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DUF1761 PF08570.5 EKG21529.1 - 5.4e-24 84.6 0.7 6e-24 84.4 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) VGLL4 PF15245.1 EKG21530.1 - 0.36 10.6 6.5 0.076 12.8 1.5 1.8 1 1 1 2 2 2 0 Transcription cofactor vestigial-like protein 4 Glutaredoxin PF00462.19 EKG21531.1 - 2e-16 59.6 0.0 4.3e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.14 EKG21532.1 - 4.3e-38 129.8 0.0 1.8e-37 127.9 0.0 2.0 2 1 0 2 2 2 1 Flavoprotein AFG1_ATPase PF03969.11 EKG21534.1 - 2.9e-30 105.3 0.0 2.9e-22 78.9 0.0 3.2 3 0 0 3 3 3 3 AFG1-like ATPase DUF2909 PF11137.3 EKG21537.1 - 0.11 12.2 0.2 0.11 12.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) DUF1705 PF08019.7 EKG21537.1 - 5.2 6.5 9.8 4.1 6.8 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) Toxin_62 PF15540.1 EKG21541.1 - 0.071 13.2 0.2 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 Putative toxin 62 HATPase_c_3 PF13589.1 EKG21552.1 - 1.4e-17 63.6 0.0 3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EKG21552.1 - 1.4e-06 27.9 0.1 0.00029 20.4 0.0 3.5 3 1 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EKG21552.1 - 0.00031 20.4 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNF PF00209.13 EKG21556.1 - 0.07 11.5 0.0 0.08 11.3 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family FAD_binding_4 PF01565.18 EKG21558.1 - 9.7e-19 67.2 0.0 1.6e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF35_N PF12172.3 EKG21559.1 - 0.47 10.4 2.0 0.49 10.3 0.1 1.9 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) AIP3 PF03915.8 EKG21561.1 - 1.1e-158 528.6 16.0 2.2e-158 527.6 11.1 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EKG21561.1 - 0.02 14.2 0.1 0.02 14.2 0.1 3.1 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 EKG21561.1 - 7.8 6.3 9.4 1.6 8.5 0.6 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) LsmAD PF06741.8 EKG21562.1 - 8.7e-26 89.8 1.1 8.7e-26 89.8 0.8 2.6 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.1 EKG21562.1 - 1.4e-16 60.1 0.0 5.1e-16 58.3 0.0 2.1 1 0 0 1 1 1 1 Ataxin 2 SM domain ABC1 PF03109.11 EKG21563.1 - 1.1e-32 112.4 0.0 1.8e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EKG21563.1 - 1.8 8.2 7.9 22 4.6 4.7 2.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.20 EKG21564.1 - 1.8e-93 313.2 0.0 2.4e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EKG21564.1 - 2.9e-33 113.3 16.0 4.5e-11 42.3 0.7 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EKG21564.1 - 1.6e-16 59.9 0.0 3.5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF4066 PF13278.1 EKG21566.1 - 3.1e-17 62.3 0.0 3.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EKG21566.1 - 4.2e-09 36.0 0.0 5.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family PRELI PF04707.9 EKG21567.1 - 1.7e-43 147.9 0.1 2e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 EKG21567.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PNGaseA PF12222.3 EKG21568.1 - 1.8e-137 458.7 3.5 1.8e-137 458.7 2.4 1.6 2 0 0 2 2 2 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1279 PF06916.8 EKG21570.1 - 2.1e-29 101.6 0.0 3.1e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Sugar_tr PF00083.19 EKG21571.1 - 9.5e-143 476.0 25.7 1.1e-142 475.8 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG21571.1 - 1.1e-26 93.4 36.7 1.6e-16 60.0 10.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EKG21571.1 - 0.041 13.8 1.6 0.2 11.6 1.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) zf-C2H2 PF00096.21 EKG21573.1 - 5.1e-09 35.9 10.2 0.012 15.8 0.1 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG21573.1 - 0.00013 22.0 15.6 0.02 15.1 0.2 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-Di19 PF05605.7 EKG21573.1 - 0.51 10.5 7.9 0.54 10.4 0.5 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Asp-B-Hydro_N PF05279.6 EKG21574.1 - 0.0055 16.5 13.1 0.0081 16.0 9.1 1.2 1 0 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region FYDLN_acid PF09538.5 EKG21574.1 - 0.35 11.4 6.8 1.3 9.6 4.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NAM-associated PF14303.1 EKG21574.1 - 0.83 9.9 16.4 1.5 9.0 11.3 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DDHD PF02862.12 EKG21574.1 - 1.6 8.4 6.3 2.5 7.8 4.3 1.3 1 0 0 1 1 1 0 DDHD domain DUF4613 PF15390.1 EKG21574.1 - 3.6 5.6 5.7 4.1 5.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) RR_TM4-6 PF06459.7 EKG21574.1 - 5.8 6.7 15.1 9.2 6.0 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.11 EKG21574.1 - 7.6 5.8 6.0 12 5.2 4.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FAD_binding_3 PF01494.14 EKG21575.1 - 1.9e-12 46.8 0.0 2.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pol_alpha_B_N PF08418.5 EKG21576.1 - 7.4 6.0 15.9 0.18 11.2 0.1 3.2 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal PNK3P PF08645.6 EKG21577.1 - 9.9e-54 181.0 0.0 1.6e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EKG21577.1 - 1.6e-30 105.8 0.0 1.2e-29 103.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EKG21577.1 - 0.0027 16.8 0.0 0.017 14.1 0.0 2.0 1 1 1 2 2 2 1 Zeta toxin HAD_2 PF13419.1 EKG21577.1 - 0.018 15.2 0.2 2 8.6 0.0 3.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_22 PF13401.1 EKG21577.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Med18 PF09637.5 EKG21578.1 - 2.8e-49 167.9 0.1 3.1e-49 167.7 0.1 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EKG21579.1 - 4.6e-38 130.6 1.7 5.3e-38 130.5 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) ALAD PF00490.16 EKG21580.1 - 3.8e-116 387.5 0.0 4.3e-116 387.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase NAM PF02365.10 EKG21582.1 - 0.12 12.5 0.6 0.38 10.9 0.3 1.8 1 1 1 2 2 2 0 No apical meristem (NAM) protein Cyto_heme_lyase PF01265.12 EKG21583.1 - 1.2e-83 280.6 0.0 1.3e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase HALZ PF02183.13 EKG21584.1 - 0.21 11.3 1.4 0.25 11.1 0.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper MFS_1 PF07690.11 EKG21585.1 - 2.1e-16 59.5 25.5 2.1e-16 59.5 17.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EKG21586.1 - 0.0037 16.1 0.0 0.0042 15.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tcp11 PF05794.8 EKG21587.1 - 2.2e-70 237.6 0.0 4e-70 236.7 0.0 1.4 1 0 0 1 1 1 1 T-complex protein 11 Fungal_trans PF04082.13 EKG21588.1 - 6.5e-28 97.3 0.0 1.8e-27 95.8 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain DHquinase_I PF01487.10 EKG21589.1 - 9.8e-60 201.9 0.0 1.4e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Pkinase PF00069.20 EKG21591.1 - 9.6e-50 169.1 0.1 8.4e-34 116.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21591.1 - 1.8e-23 82.9 0.0 1e-21 77.2 0.0 3.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG21591.1 - 1.7e-05 23.9 0.0 6.6e-05 21.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Glyco_transf_22 PF03901.12 EKG21592.1 - 1.2e-06 27.7 0.1 1.5e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3984 PF13136.1 EKG21593.1 - 2.8e-61 207.5 29.8 8.6e-61 205.9 16.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3984) DUF1032 PF06278.6 EKG21593.1 - 0.084 11.3 2.1 0.13 10.7 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1032) Y_phosphatase2 PF03162.8 EKG21594.1 - 3.5e-45 153.3 0.0 4.6e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EKG21594.1 - 1.3e-10 41.7 0.1 1.2e-09 38.5 0.1 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EKG21594.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EKG21594.1 - 0.025 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Myotub-related PF06602.9 EKG21594.1 - 0.048 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain EamA PF00892.15 EKG21595.1 - 4.2e-22 78.5 24.2 7.7e-15 55.0 2.7 2.9 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EKG21595.1 - 3.6e-05 23.9 6.8 3.6e-05 23.9 4.7 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter RseC_MucC PF04246.7 EKG21595.1 - 8.3 5.9 8.8 6.7 6.2 0.0 3.7 3 1 2 5 5 5 0 Positive regulator of sigma(E), RseC/MucC Chorismate_synt PF01264.16 EKG21598.1 - 2.1e-127 424.4 0.0 2.7e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase eIF_4EBP PF05456.6 EKG21599.1 - 0.098 12.3 1.4 0.13 11.9 0.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3431 PF11913.3 EKG21601.1 - 6.3e-58 195.8 0.0 6.9e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Sugar_tr PF00083.19 EKG21603.1 - 7e-93 311.6 28.1 8.2e-93 311.4 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG21603.1 - 4.2e-29 101.3 26.2 4.2e-29 101.3 18.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG21603.1 - 0.00077 17.7 1.1 0.00077 17.7 0.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG21604.1 - 2.7e-17 62.5 42.0 5.2e-12 45.1 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EKG21604.1 - 7.1e-12 44.3 20.7 1.1e-11 43.7 14.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fst_toxin PF13955.1 EKG21604.1 - 0.35 10.5 3.3 0.88 9.3 2.3 1.7 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system Ras PF00071.17 EKG21605.1 - 5.5e-53 178.6 0.0 6.4e-53 178.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EKG21605.1 - 7.3e-16 58.7 0.0 1.2e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EKG21605.1 - 2.3e-06 26.9 0.0 3.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Hemerythrin PF01814.18 EKG21607.1 - 0.0013 18.8 1.4 0.65 10.1 0.2 2.2 2 0 0 2 2 2 1 Hemerythrin HHE cation binding domain zf-C4H2 PF10146.4 EKG21607.1 - 0.0025 17.8 1.0 0.0025 17.8 0.7 1.4 1 1 1 2 2 1 1 Zinc finger-containing protein IncA PF04156.9 EKG21607.1 - 0.0031 17.1 1.2 0.0031 17.1 0.8 1.9 2 0 0 2 2 2 1 IncA protein Lzipper-MIP1 PF14389.1 EKG21607.1 - 0.0034 17.4 1.7 0.0089 16.1 1.1 1.7 1 1 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 Tektin PF03148.9 EKG21607.1 - 0.0042 15.6 2.6 0.022 13.3 1.8 1.9 1 1 0 1 1 1 1 Tektin family BicD PF09730.4 EKG21607.1 - 0.0064 14.9 1.6 0.0084 14.5 1.1 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D DUF1465 PF07323.7 EKG21607.1 - 0.0093 15.5 0.5 0.019 14.5 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1465) Baculo_PEP_C PF04513.7 EKG21607.1 - 0.01 15.6 0.4 0.018 14.8 0.2 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.6 EKG21607.1 - 0.011 14.0 2.1 0.014 13.6 1.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Apolipoprotein PF01442.13 EKG21607.1 - 0.012 15.1 0.1 0.02 14.4 0.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FliD_C PF07195.7 EKG21607.1 - 0.014 14.7 0.9 0.022 14.0 0.6 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF848 PF05852.6 EKG21607.1 - 0.016 15.0 0.8 0.016 15.0 0.6 2.0 2 1 1 3 3 2 0 Gammaherpesvirus protein of unknown function (DUF848) RmuC PF02646.11 EKG21607.1 - 0.017 14.0 2.9 0.083 11.7 0.1 2.1 1 1 1 2 2 2 0 RmuC family BAR PF03114.13 EKG21607.1 - 0.024 14.1 1.3 0.039 13.4 0.9 1.3 1 0 0 1 1 1 0 BAR domain Spc7 PF08317.6 EKG21607.1 - 0.025 13.2 2.6 0.034 12.7 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein RNase_E_G PF10150.4 EKG21607.1 - 0.025 13.8 1.6 0.038 13.2 0.2 1.7 1 1 1 2 2 2 0 Ribonuclease E/G family Myosin_tail_1 PF01576.14 EKG21607.1 - 0.033 11.9 3.7 0.043 11.5 2.6 1.1 1 0 0 1 1 1 0 Myosin tail Filament PF00038.16 EKG21607.1 - 0.034 13.5 4.2 0.076 12.4 2.9 1.5 1 1 0 1 1 1 0 Intermediate filament protein Lectin_N PF03954.9 EKG21607.1 - 0.035 13.5 0.5 0.035 13.5 0.4 1.8 2 0 0 2 2 1 0 Hepatic lectin, N-terminal domain CENP-F_leu_zip PF10473.4 EKG21607.1 - 0.036 13.9 4.8 0.66 9.8 0.1 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EKG21607.1 - 0.037 14.2 0.7 0.35 11.1 0.5 2.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Phasin PF05597.6 EKG21607.1 - 0.049 13.4 1.9 0.1 12.3 1.3 1.6 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PIN_2 PF10130.4 EKG21607.1 - 0.049 13.6 0.3 0.092 12.7 0.1 1.5 1 1 0 1 1 1 0 PIN domain Mer2 PF09074.5 EKG21607.1 - 0.062 13.2 1.2 0.087 12.7 0.8 1.1 1 0 0 1 1 1 0 Mer2 RE_ApaLI PF09499.5 EKG21607.1 - 0.073 12.4 3.2 0.44 9.8 0.6 2.1 2 0 0 2 2 2 0 ApaLI-like restriction endonuclease DUF892 PF05974.7 EKG21607.1 - 0.081 12.7 0.6 7.5 6.3 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF892) HSBP1 PF06825.7 EKG21607.1 - 0.089 12.3 1.4 0.95 9.0 0.0 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 APG6 PF04111.7 EKG21607.1 - 0.095 11.7 4.1 0.14 11.1 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EKG21607.1 - 0.1 12.7 4.8 4 7.6 3.4 2.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filo_VP35 PF02097.10 EKG21607.1 - 0.1 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Filoviridae VP35 PspB PF06667.7 EKG21607.1 - 0.12 12.3 0.2 0.42 10.5 0.0 2.0 2 0 0 2 2 1 0 Phage shock protein B Prominin PF05478.6 EKG21607.1 - 0.12 9.9 0.8 0.16 9.5 0.5 1.1 1 0 0 1 1 1 0 Prominin Mnd1 PF03962.10 EKG21607.1 - 0.12 12.0 2.6 0.18 11.4 1.2 1.6 1 1 0 1 1 1 0 Mnd1 family DUF4407 PF14362.1 EKG21607.1 - 0.12 11.2 0.1 0.24 10.3 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.6 EKG21607.1 - 0.13 12.1 1.8 8.5 6.3 0.9 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.4 EKG21607.1 - 0.16 10.7 3.5 3.1 6.4 0.1 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DivIVA PF05103.8 EKG21607.1 - 0.16 11.9 3.1 1.2 9.2 0.8 2.6 1 1 2 3 3 3 0 DivIVA protein GAS PF13851.1 EKG21607.1 - 0.18 11.0 6.8 0.68 9.0 3.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3552 PF12072.3 EKG21607.1 - 0.32 10.1 3.9 0.4 9.8 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) bZIP_1 PF00170.16 EKG21607.1 - 0.38 10.7 2.3 0.48 10.4 0.9 1.7 2 0 0 2 2 1 0 bZIP transcription factor TBPIP PF07106.8 EKG21607.1 - 0.67 9.4 4.8 1.7 8.1 2.2 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EKG21607.1 - 0.69 9.7 6.0 0.26 11.1 1.5 2.2 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding PhoU PF01895.14 EKG21607.1 - 0.76 10.2 5.3 4.2 7.8 0.2 2.2 1 1 1 2 2 2 0 PhoU domain DUF2458 PF10454.4 EKG21607.1 - 1 9.2 8.5 0.02 14.7 1.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF2458) Muted PF14942.1 EKG21607.1 - 1.1 9.1 7.5 0.15 11.9 2.4 1.6 2 0 0 2 2 1 0 Organelle biogenesis, Muted-like protein ADIP PF11559.3 EKG21607.1 - 2.9 7.7 8.3 0.21 11.5 1.7 1.8 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding Fib_alpha PF08702.5 EKG21607.1 - 4.4 7.4 6.2 1.7 8.7 1.4 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 EKG21607.1 - 6.3 7.2 10.2 3.1 8.1 1.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EKG21607.1 - 7.2 6.3 7.8 1.9 8.1 0.8 2.5 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.20 EKG21608.1 - 2.5e-49 167.7 0.0 3.4e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21608.1 - 4.5e-27 94.7 0.0 7.2e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG21608.1 - 0.028 13.3 0.0 0.38 9.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like AA_permease_2 PF13520.1 EKG21609.1 - 1.2e-53 182.1 45.5 1.6e-53 181.7 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG21609.1 - 4.1e-24 84.7 39.0 6.6e-24 84.0 27.0 1.2 1 0 0 1 1 1 1 Amino acid permease Flavin_Reduct PF01613.13 EKG21611.1 - 6.7e-16 58.5 0.0 8.4e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain adh_short PF00106.20 EKG21612.1 - 9.1e-07 28.9 1.1 0.0061 16.4 0.8 3.1 2 2 0 2 2 2 2 short chain dehydrogenase Ser_hydrolase PF06821.8 EKG21612.1 - 0.076 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase Translin PF01997.11 EKG21614.1 - 1.4e-59 201.1 0.0 1.8e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Translin family Mannosyl_trans PF05007.8 EKG21615.1 - 1.1e-79 267.7 17.5 1.1e-79 267.7 12.1 1.4 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EKG21615.1 - 1.7e-13 50.1 6.5 1.7e-13 50.1 4.5 2.1 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EKG21615.1 - 1.8e-05 24.3 18.1 1.8e-05 24.3 12.6 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) Lipase_GDSL PF00657.17 EKG21617.1 - 4.1e-18 66.0 0.0 6.1e-18 65.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKG21617.1 - 4.2e-16 59.6 0.0 5.5e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Voltage_CLC PF00654.15 EKG21618.1 - 3.9e-95 318.8 25.6 1.5e-94 316.9 15.0 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EKG21618.1 - 0.0033 17.1 0.0 0.64 9.8 0.0 2.7 3 0 0 3 3 3 2 CBS domain Metal_resist PF13801.1 EKG21618.1 - 0.028 14.4 0.8 0.062 13.2 0.5 1.5 1 0 0 1 1 1 0 Heavy-metal resistance Cpn60_TCP1 PF00118.19 EKG21619.1 - 1.7e-137 458.9 9.1 1.9e-137 458.8 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 EKG21619.1 - 0.0098 15.9 0.0 0.04 13.9 0.0 2.1 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor EAL PF00563.15 EKG21619.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 EAL domain Mcp5_PH PF12814.2 EKG21620.1 - 2.7e-42 143.5 0.2 5.6e-42 142.5 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF641 PF04859.7 EKG21620.1 - 3.3 7.4 19.4 5.7 6.7 4.3 3.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) ALMT PF11744.3 EKG21620.1 - 6.3 5.3 5.0 1.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter Filament PF00038.16 EKG21620.1 - 6.7 6.0 36.2 0.23 10.9 7.3 4.5 2 1 3 5 5 5 0 Intermediate filament protein EST1_DNA_bind PF10373.4 EKG21621.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain zf-CCCH PF00642.19 EKG21622.1 - 2.4e-08 33.4 2.4 4.5e-08 32.5 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EKG21622.1 - 2.9e-08 33.5 10.6 5.2e-08 32.7 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG21622.1 - 2.3e-07 30.4 9.1 3.9e-07 29.6 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EKG21622.1 - 3.3e-07 29.8 6.4 6e-07 29.0 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EKG21622.1 - 4.1e-07 29.7 7.5 6.6e-07 29.0 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EKG21622.1 - 4.7e-07 29.3 10.6 8.5e-07 28.5 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EKG21622.1 - 0.00016 21.3 4.3 0.00041 20.0 3.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EKG21622.1 - 0.0032 17.3 8.6 0.0074 16.1 6.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EKG21622.1 - 0.018 14.5 3.5 0.031 13.7 2.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 EKG21622.1 - 0.023 15.0 2.5 0.082 13.2 1.7 2.0 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.2 EKG21622.1 - 0.72 10.0 5.9 1.6 8.8 4.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger HD PF01966.17 EKG21623.1 - 3.9e-07 30.1 0.0 5.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 HD domain Glyco_hydro_88 PF07470.8 EKG21624.1 - 3.2e-48 164.4 0.5 3.9e-48 164.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.16 EKG21624.1 - 0.055 12.4 0.0 0.28 10.1 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II MFS_1 PF07690.11 EKG21625.1 - 1.2e-36 126.1 40.9 1.2e-36 126.1 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21625.1 - 1e-10 40.7 23.8 3.4e-10 39.0 16.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter SAGA-Tad1 PF12767.2 EKG21625.1 - 1.7 8.2 3.6 23 4.5 1.3 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit MSP PF01716.13 EKG21626.1 - 0.063 12.3 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide LMP PF04778.7 EKG21627.1 - 0.033 13.9 0.4 0.68 9.6 0.0 2.5 1 1 0 2 2 2 0 LMP repeated region SIN1 PF05422.7 EKG21630.1 - 8.4e-36 123.5 0.9 2.3e-19 69.3 0.5 2.2 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EKG21630.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 GLUT4 regulating protein TUG PBP1_TM PF14812.1 EKG21630.1 - 1.3 9.4 11.1 0.48 10.7 1.6 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PRCC PF10253.4 EKG21631.1 - 7.5e-39 134.2 1.4 7.5e-39 134.2 1.0 3.1 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Meiotic_rec114 PF03525.9 EKG21632.1 - 0.0019 16.7 0.2 0.0029 16.1 0.1 1.4 1 1 0 1 1 1 1 Meiotic recombination protein rec114 Myc-LZ PF02344.10 EKG21632.1 - 0.043 13.4 0.1 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 Myc leucine zipper domain HCO3_cotransp PF00955.16 EKG21633.1 - 4.7e-52 177.3 12.9 6.4e-27 94.3 0.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family MMR_HSR1 PF01926.18 EKG21634.1 - 8.8e-14 51.4 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EKG21634.1 - 7.6e-05 22.0 0.1 0.00012 21.4 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.8 EKG21634.1 - 0.0022 16.8 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EKG21634.1 - 0.0025 17.0 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EKG21634.1 - 0.0042 16.9 1.6 0.37 10.5 0.0 2.7 3 0 0 3 3 3 2 Dynamin family AIG1 PF04548.11 EKG21634.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Septin PF00735.13 EKG21634.1 - 0.086 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin Thy1 PF02511.10 EKG21635.1 - 0.053 12.8 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase complementing protein DUF897 PF05982.7 EKG21640.1 - 0.13 11.0 2.5 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF897) DUF3087 PF11286.3 EKG21640.1 - 0.55 9.4 4.1 0.35 10.0 0.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3087) Glyco_hydro_61 PF03443.9 EKG21641.1 - 7.9e-22 78.1 2.5 1e-21 77.7 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Toxin_50 PF15530.1 EKG21641.1 - 0.024 14.5 0.1 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 50 Cellulase PF00150.13 EKG21642.1 - 2.4e-19 69.5 2.3 2e-18 66.6 1.6 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EKG21642.1 - 0.002 17.1 0.1 0.0058 15.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EKG21642.1 - 0.011 14.9 0.1 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 Beta-galactosidase Glyoxalase_2 PF12681.2 EKG21642.1 - 0.012 16.2 0.0 0.044 14.3 0.0 2.0 2 0 0 2 2 2 0 Glyoxalase-like domain GCN5L1 PF06320.8 EKG21643.1 - 5.5e-15 55.2 3.5 6.3e-15 55.0 2.5 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) ABC_tran_2 PF12848.2 EKG21643.1 - 0.00041 20.1 3.2 0.00061 19.5 2.3 1.2 1 0 0 1 1 1 1 ABC transporter POM121 PF15229.1 EKG21643.1 - 0.032 13.6 1.0 0.036 13.4 0.7 1.1 1 0 0 1 1 1 0 POM121 family zf-C4H2 PF10146.4 EKG21643.1 - 0.054 13.5 0.7 0.058 13.4 0.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DOR PF14839.1 EKG21643.1 - 0.055 13.2 3.3 0.06 13.0 2.3 1.1 1 0 0 1 1 1 0 DOR family Syntaxin-6_N PF09177.6 EKG21643.1 - 0.075 13.4 3.2 0.85 10.0 1.1 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HAUS6_N PF14661.1 EKG21643.1 - 0.092 12.0 5.1 0.1 11.9 3.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4337 PF14235.1 EKG21643.1 - 0.2 11.5 5.6 0.25 11.1 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Atg14 PF10186.4 EKG21643.1 - 0.3 9.9 3.0 0.33 9.8 2.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WXG100 PF06013.7 EKG21643.1 - 0.8 9.7 8.4 3.9 7.5 5.7 2.2 1 1 0 1 1 1 0 Proteins of 100 residues with WXG DivIC PF04977.10 EKG21643.1 - 1.6 8.2 4.7 2.6 7.5 3.3 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF913 PF06025.7 EKG21644.1 - 8.1e-118 393.4 0.0 8.1e-118 393.4 0.0 4.6 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) HECT PF00632.20 EKG21644.1 - 3.9e-99 331.8 0.1 6.8e-99 331.0 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EKG21644.1 - 5.3e-82 275.7 0.0 5.3e-82 275.7 0.0 4.1 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EKG21644.1 - 5.6e-27 93.7 6.5 5.6e-27 93.7 4.5 4.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4414) Ctf8 PF09696.5 EKG21646.1 - 1.7e-35 121.4 0.0 2e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Clat_adaptor_s PF01217.15 EKG21647.1 - 4.5e-30 104.2 0.0 5.3e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 EKG21648.1 - 5.3e-31 106.6 0.0 7.2e-31 106.2 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.8 EKG21649.1 - 4.1e-26 90.2 0.7 5.2e-26 89.9 0.5 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EKG21649.1 - 0.017 15.0 0.2 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF2457 PF10446.4 EKG21650.1 - 1.9e-06 26.8 3.3 2.2e-06 26.7 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 EKG21650.1 - 0.17 9.7 0.9 0.22 9.3 0.6 1.1 1 0 0 1 1 1 0 Nop14-like family Anophelin PF10731.4 EKG21650.1 - 0.28 11.3 0.1 0.28 11.3 0.1 2.6 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Herpes_LMP1 PF05297.6 EKG21650.1 - 6.2 5.6 14.3 10 4.9 9.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Peptidase_M35 PF02102.10 EKG21651.1 - 9.4e-14 50.8 0.0 1.1e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EKG21651.1 - 5.2e-07 30.2 0.0 5.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase p450 PF00067.17 EKG21652.1 - 0.043 12.3 0.0 0.046 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 PNP_UDP_1 PF01048.15 EKG21653.1 - 0.00026 20.0 0.0 0.00093 18.2 0.0 1.9 1 1 0 1 1 1 1 Phosphorylase superfamily Glyco_transf_28 PF03033.15 EKG21655.1 - 1.2e-24 86.7 0.0 2e-24 85.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain zf-Tim10_DDP PF02953.10 EKG21655.1 - 0.037 13.3 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger CENP-N PF05238.8 EKG21655.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like ADH_N PF08240.7 EKG21657.1 - 2.3e-26 91.6 1.5 8.4e-26 89.8 1.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG21657.1 - 4.3e-15 55.4 0.0 1.7e-13 50.2 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EKG21657.1 - 0.00065 18.9 0.2 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EKG21657.1 - 0.23 11.0 1.2 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.7 EKG21658.1 - 3.3e-29 100.8 1.7 3.3e-29 100.8 1.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG21658.1 - 1.7e-28 98.7 0.0 2.8e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG21658.1 - 1.1e-05 26.3 0.0 2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.1 EKG21658.1 - 0.00012 22.3 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_N_assoc PF13823.1 EKG21658.1 - 0.00022 20.7 0.0 0.00071 19.1 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 EKG21658.1 - 0.0045 16.9 0.0 0.029 14.3 0.0 2.3 2 1 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.22 EKG21658.1 - 0.0081 16.5 0.0 0.047 14.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG21658.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EKG21658.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EKG21658.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EKG21658.1 - 0.037 14.1 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain KR PF08659.5 EKG21658.1 - 0.046 13.3 0.1 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Pyr_redox_2 PF07992.9 EKG21658.1 - 0.094 12.5 0.3 0.18 11.6 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EKG21658.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MARVEL PF01284.18 EKG21659.1 - 2.2e-05 24.2 6.0 3.5e-05 23.6 4.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain TMEM190 PF15431.1 EKG21659.1 - 0.011 15.7 0.3 0.022 14.6 0.2 1.5 1 1 0 1 1 1 0 Transmembrane protein 190 YrhK PF14145.1 EKG21659.1 - 0.035 13.7 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 YrhK-like protein YwiC PF14256.1 EKG21659.1 - 0.11 12.5 2.8 3.6 7.7 0.5 2.3 2 0 0 2 2 2 0 YwiC-like protein DUF1469 PF07332.6 EKG21659.1 - 2.1 8.0 0.0 2.1 8.0 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) PGA2 PF07543.7 EKG21661.1 - 1.6e-31 108.9 0.4 2e-31 108.6 0.3 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 Chitin_bind_3 PF03067.10 EKG21662.1 - 0.0042 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Chitin binding domain Cupin_6 PF12852.2 EKG21663.1 - 6e-06 26.0 0.0 7.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EKG21663.1 - 0.00031 20.4 0.1 0.00058 19.5 0.1 1.5 1 1 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.6 EKG21663.1 - 0.0031 16.9 0.1 0.0066 15.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EKG21663.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.7 EKG21663.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) CFEM PF05730.6 EKG21665.1 - 1.9e-11 43.5 14.1 2.9e-11 43.0 9.8 1.3 1 0 0 1 1 1 1 CFEM domain Herpes_DNAp_acc PF04929.7 EKG21665.1 - 0.49 9.3 5.8 0.61 9.0 4.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3237 PF11578.3 EKG21666.1 - 1.1e-32 112.3 0.0 1.7e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Glyco_hydro_43 PF04616.9 EKG21667.1 - 1.5e-11 43.9 6.9 8.3e-10 38.2 2.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Pectate_lyase PF03211.8 EKG21670.1 - 8e-37 126.7 0.9 1.1e-36 126.2 0.6 1.1 1 0 0 1 1 1 1 Pectate lyase DUF3328 PF11807.3 EKG21672.1 - 9.5e-15 54.8 3.3 1.4e-13 51.0 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3328) DUF2897 PF11446.3 EKG21672.1 - 0.039 13.7 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Peptidase_S8 PF00082.17 EKG21674.1 - 7.1e-48 163.1 0.0 9.7e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EKG21674.1 - 6.1e-08 32.2 0.0 1.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EKG21674.1 - 8.4e-08 32.6 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Herpes_LAMP2 PF06126.6 EKG21675.1 - 0.029 12.8 0.0 0.037 12.4 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 FLILHELTA PF10306.4 EKG21676.1 - 0.003 17.5 0.1 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF2970 PF11174.3 EKG21679.1 - 0.48 10.0 3.9 1.2 8.7 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Asp PF00026.18 EKG21681.1 - 4.9e-42 144.2 2.3 6.6e-42 143.8 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EKG21681.1 - 2.7e-08 33.9 0.0 1.9e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EKG21681.1 - 0.0066 16.9 0.7 0.026 14.9 0.5 2.0 1 1 0 1 1 1 1 Aspartyl protease SurE PF01975.12 EKG21682.1 - 4.8e-26 91.2 0.5 7.3e-26 90.6 0.3 1.3 1 0 0 1 1 1 1 Survival protein SurE DUF2944 PF11161.3 EKG21683.1 - 0.082 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) RHS PF03527.9 EKG21683.1 - 0.16 11.7 0.9 10 6.0 0.1 2.3 2 0 0 2 2 2 0 RHS protein DUF1469 PF07332.6 EKG21684.1 - 0.34 10.6 2.1 0.47 10.1 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) GMC_oxred_N PF00732.14 EKG21685.1 - 7.4e-61 205.8 0.0 1e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG21685.1 - 2.5e-31 108.8 0.7 5.8e-31 107.7 0.5 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG21685.1 - 4e-05 22.6 1.3 0.0067 15.3 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG21685.1 - 4.3e-05 22.5 1.1 0.0079 15.0 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EKG21685.1 - 0.00027 19.9 0.3 0.00043 19.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG21685.1 - 0.00059 19.8 0.3 0.0022 17.9 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EKG21685.1 - 0.014 13.8 0.2 0.077 11.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 EKG21685.1 - 0.059 13.2 0.0 0.17 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EKG21686.1 - 1.1e-19 70.4 27.9 1.1e-19 70.4 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BMFP PF04380.8 EKG21687.1 - 0.0039 17.2 1.3 0.0062 16.6 0.9 1.3 1 0 0 1 1 1 1 Membrane fusogenic activity IncA PF04156.9 EKG21687.1 - 0.0074 15.9 0.9 0.0087 15.6 0.6 1.1 1 0 0 1 1 1 1 IncA protein DUF3552 PF12072.3 EKG21687.1 - 0.0078 15.4 1.1 0.0085 15.3 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) AAA_13 PF13166.1 EKG21687.1 - 0.0083 14.6 0.8 0.0092 14.5 0.5 1.0 1 0 0 1 1 1 1 AAA domain Cast PF10174.4 EKG21687.1 - 0.0084 14.2 0.2 0.009 14.1 0.1 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone TMF_DNA_bd PF12329.3 EKG21687.1 - 0.0092 15.7 1.2 0.013 15.2 0.9 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Phage_lysis PF03245.8 EKG21687.1 - 0.011 15.7 0.4 0.014 15.4 0.3 1.2 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein ERM PF00769.14 EKG21687.1 - 0.011 15.3 1.1 0.011 15.2 0.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family MerR-DNA-bind PF09278.6 EKG21687.1 - 0.013 15.8 1.1 0.019 15.3 0.8 1.3 1 0 0 1 1 1 0 MerR, DNA binding IFT57 PF10498.4 EKG21687.1 - 0.023 13.4 0.7 0.027 13.2 0.5 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.1 EKG21687.1 - 0.04 12.8 1.1 0.045 12.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EKG21687.1 - 0.046 13.4 0.8 0.065 12.9 0.6 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein OmpH PF03938.9 EKG21687.1 - 0.054 13.4 1.7 0.063 13.2 1.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Trypan_glycop PF00913.14 EKG21687.1 - 0.061 12.2 0.2 0.076 11.9 0.1 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) SlyX PF04102.7 EKG21687.1 - 0.083 13.2 0.7 0.14 12.5 0.5 1.5 1 1 0 1 1 1 0 SlyX NPV_P10 PF05531.7 EKG21687.1 - 0.096 12.9 0.1 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Sugarporin_N PF11471.3 EKG21687.1 - 0.82 9.3 6.7 0.14 11.7 1.4 1.9 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF4140 PF13600.1 EKG21687.1 - 1.2 9.5 5.0 1.5 9.3 3.1 1.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Bromodomain PF00439.20 EKG21688.1 - 4.4e-22 77.7 0.0 1.4e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Bromodomain AA_permease PF00324.16 EKG21689.1 - 4.5e-33 114.3 23.6 6e-32 110.6 16.4 2.4 1 1 0 1 1 1 1 Amino acid permease L_protein_N PF15518.1 EKG21690.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 L protein N-terminus PspB PF06667.7 EKG21690.1 - 0.31 11.0 1.5 4.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Phage shock protein B Pkinase PF00069.20 EKG21691.1 - 6.6e-20 71.3 0.0 1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21691.1 - 2.4e-06 26.8 0.0 4.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_3 PF07859.8 EKG21692.1 - 3.4e-26 92.1 0.3 4.5e-26 91.7 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG21692.1 - 0.14 10.7 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family RasGEF PF00617.14 EKG21694.1 - 3.1e-47 160.7 0.0 1.1e-46 158.9 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EKG21694.1 - 4.8e-14 52.3 0.1 1.3e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EKG21694.1 - 1.9e-11 44.4 0.0 8.1e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EKG21694.1 - 1.2e-06 28.0 0.1 2.1e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 Ras family AAA_16 PF13191.1 EKG21694.1 - 0.011 15.7 0.0 0.13 12.2 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain Mucin PF01456.12 EKG21696.1 - 0.025 14.3 12.2 0.035 13.8 8.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein AA_permease_2 PF13520.1 EKG21697.1 - 3.6e-54 183.9 47.1 4.5e-54 183.5 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG21697.1 - 1.8e-24 85.9 40.5 2.2e-24 85.6 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease Oxidored_FMN PF00724.15 EKG21699.1 - 4.5e-87 292.2 0.0 5.3e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GMC_oxred_C PF05199.8 EKG21701.1 - 4.5e-36 124.2 0.5 4.5e-36 124.2 0.3 1.9 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EKG21701.1 - 7.6e-32 110.6 0.0 1.1e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_S8 PF00082.17 EKG21702.1 - 3.7e-28 98.4 0.1 3.7e-28 98.4 0.1 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EKG21702.1 - 0.089 12.4 0.1 0.43 10.2 0.0 2.1 3 0 0 3 3 3 0 PA domain DUF1034 PF06280.7 EKG21703.1 - 9.5e-09 35.6 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Y_Y_Y PF07495.8 EKG21703.1 - 0.11 12.3 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Y_Y_Y domain Methyltransf_23 PF13489.1 EKG21704.1 - 1.9e-05 24.4 0.0 9e-05 22.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain CBP PF12192.3 EKG21705.1 - 0.0029 17.5 7.8 0.0029 17.5 5.4 3.3 2 1 1 3 3 3 2 Fungal calcium binding protein TPR_2 PF07719.12 EKG21706.1 - 1.6e-11 43.1 9.4 9.2e-05 22.0 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EKG21706.1 - 2.2e-11 43.2 14.2 5.4e-07 29.1 0.0 4.6 6 0 0 6 6 6 2 TPR repeat TPR_1 PF00515.23 EKG21706.1 - 1.5e-06 27.5 3.4 0.0069 15.9 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EKG21706.1 - 0.00045 19.8 0.0 0.47 10.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EKG21706.1 - 0.0016 18.7 12.1 1.1 9.6 0.7 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EKG21706.1 - 0.0037 16.9 4.2 3.1 7.7 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat PSII PF00421.14 EKG21706.1 - 0.0046 15.6 0.0 0.0065 15.1 0.0 1.1 1 0 0 1 1 1 1 Photosystem II protein TPR_16 PF13432.1 EKG21706.1 - 0.005 17.4 37.0 0.044 14.4 0.0 7.9 9 1 1 10 10 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EKG21706.1 - 0.022 14.6 16.5 0.06 13.2 2.6 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG21706.1 - 0.099 13.3 27.1 6.7 7.6 0.0 8.0 8 3 2 10 10 9 0 Tetratricopeptide repeat MIT PF04212.13 EKG21706.1 - 0.4 10.5 3.1 4.2 7.3 0.0 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 EKG21706.1 - 0.85 9.9 5.3 54 4.3 0.0 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EKG21706.1 - 1.9 8.3 9.3 1.8 8.4 0.1 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.11 EKG21707.1 - 2.2e-32 112.1 71.8 1.3e-28 99.7 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EKG21707.1 - 4.1e-08 32.0 15.8 4.1e-08 32.0 11.0 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 EKG21707.1 - 3.6e-07 29.1 34.7 7.3e-06 24.8 2.3 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter Nucleo_P87 PF07267.6 EKG21708.1 - 1.1 7.8 3.6 1.5 7.3 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 IMS PF00817.15 EKG21709.1 - 1.2e-35 122.5 0.0 4.5e-35 120.6 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EKG21709.1 - 6e-11 42.3 0.1 2e-10 40.6 0.1 2.0 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EKG21709.1 - 0.0059 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF1100 PF06500.6 EKG21710.1 - 0.002 16.7 0.0 0.0021 16.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) NACHT PF05729.7 EKG21712.1 - 0.003 17.2 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain LRR_8 PF13855.1 EKG21713.1 - 8.4e-09 35.0 8.5 0.0043 16.7 0.0 5.0 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EKG21713.1 - 2.6e-07 30.0 6.1 0.14 11.8 1.1 6.2 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EKG21713.1 - 0.00027 20.6 4.1 29 5.1 0.0 6.9 6 1 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 EKG21713.1 - 0.02 14.8 3.4 44 4.6 0.0 5.5 5 1 1 6 6 6 0 Leucine Rich Repeat Trypan_PARP PF05887.6 EKG21714.1 - 0.29 10.9 6.6 0.038 13.8 1.5 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) ADH_N PF08240.7 EKG21715.1 - 2.3e-25 88.4 0.2 4.2e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG21715.1 - 8.9e-19 67.3 0.3 1.3e-18 66.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG21715.1 - 0.00045 21.1 0.4 0.00093 20.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 EKG21717.1 - 3.7e-65 219.6 0.0 6.5e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21717.1 - 1.7e-46 158.3 0.0 2.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EKG21717.1 - 4.4e-28 97.2 0.0 1e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EKG21717.1 - 6.2e-17 61.2 0.1 1.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EKG21717.1 - 2.8e-16 59.4 0.1 6.2e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EKG21717.1 - 1.2e-07 31.0 0.0 3e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 EKG21717.1 - 0.074 11.8 0.2 0.16 10.7 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 IGR PF09597.5 EKG21717.1 - 0.086 12.7 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif SAM_PNT PF02198.11 EKG21717.1 - 0.2 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Rep_fac_C PF08542.6 EKG21718.1 - 3.3e-24 84.6 0.1 6.9e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EKG21718.1 - 3.1e-10 39.9 0.0 5.8e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EKG21718.1 - 1.8e-05 24.8 0.5 0.00033 20.8 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 EKG21718.1 - 0.00015 21.9 0.1 0.00038 20.6 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EKG21718.1 - 0.00028 20.9 2.7 0.028 14.3 1.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EKG21718.1 - 0.0031 17.3 0.1 0.0078 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EKG21718.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 EKG21718.1 - 0.015 15.3 0.1 0.48 10.4 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain T4SS-DNA_transf PF02534.9 EKG21718.1 - 0.054 12.0 0.1 0.14 10.6 0.0 1.6 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 EKG21718.1 - 0.078 11.7 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EKG21718.1 - 0.1 11.9 0.1 2.6 7.3 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EKG21718.1 - 0.16 11.5 0.0 0.89 9.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Abhydrolase_3 PF07859.8 EKG21720.1 - 8.6e-36 123.4 0.0 3.2e-25 88.9 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EKG21720.1 - 0.024 13.3 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) NdhM PF10664.4 EKG21721.1 - 0.11 12.4 0.1 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Lipase_GDSL PF00657.17 EKG21723.1 - 9.1e-09 35.4 0.0 4.4e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKG21723.1 - 0.0023 18.0 0.2 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family YrhC PF14143.1 EKG21723.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 YrhC-like protein Aminotran_3 PF00202.16 EKG21724.1 - 5.2e-98 328.0 0.0 6.5e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EKG21724.1 - 8.3e-05 21.6 0.0 0.00037 19.5 0.0 1.9 3 0 0 3 3 3 1 Aminotransferase class I and II TmoB PF06234.7 EKG21724.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) DUF663 PF04950.7 EKG21725.1 - 3.4e-70 236.3 0.0 4.8e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EKG21725.1 - 3.5e-18 64.9 0.0 8.4e-18 63.6 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF4050 PF13259.1 EKG21726.1 - 6.8e-35 119.6 0.3 1e-34 119.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Vfa1 PF08432.5 EKG21726.1 - 3.6 7.5 9.3 1.7 8.6 0.4 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 eIF3_subunit PF08597.5 EKG21726.1 - 4.4 6.8 13.2 0.42 10.1 3.4 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit A2M PF00207.17 EKG21727.1 - 0.072 12.6 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Alpha-2-macroglobulin family p450 PF00067.17 EKG21728.1 - 2.4e-66 224.1 0.0 3e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_31 PF01055.21 EKG21729.1 - 1.1e-83 281.4 0.0 1.8e-83 280.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EKG21729.1 - 3.9e-05 23.4 2.6 5.4e-05 22.9 0.7 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like UPF0113 PF03657.8 EKG21730.1 - 1.3e-09 37.9 0.0 1.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EKG21730.1 - 0.013 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.6 EKG21731.1 - 1.7e-31 108.3 0.4 1.7e-31 108.3 0.3 2.4 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EKG21731.1 - 1.8e-27 95.7 0.7 5.7e-27 94.1 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family ARD PF03079.9 EKG21731.1 - 0.33 10.8 8.7 0.031 14.2 1.8 2.2 2 0 0 2 2 2 0 ARD/ARD' family IGFL PF14653.1 EKG21733.1 - 0.19 11.7 3.5 0.22 11.5 1.1 1.9 2 0 0 2 2 2 0 Insulin growth factor-like family Rhodanese PF00581.15 EKG21734.1 - 3.4e-10 40.2 0.0 5.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF1772 PF08592.6 EKG21736.1 - 0.067 12.9 0.3 0.086 12.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Voltage_CLC PF00654.15 EKG21737.1 - 7.7e-87 291.6 24.9 7.7e-87 291.6 17.3 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EKG21737.1 - 2.1e-09 37.0 0.0 0.00022 20.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain Presenilin PF01080.12 EKG21737.1 - 0.016 14.0 0.2 0.043 12.6 0.1 1.6 1 0 0 1 1 1 0 Presenilin Gly-zipper_OmpA PF13436.1 EKG21737.1 - 0.13 11.8 0.3 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Sugar_tr PF00083.19 EKG21738.1 - 1.7e-69 234.5 24.5 1.9e-69 234.4 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG21738.1 - 6.1e-16 58.0 26.0 6.1e-16 58.0 18.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EKG21740.1 - 5.7e-23 81.6 0.6 3.2e-22 79.2 0.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG21740.1 - 4.2e-15 56.1 0.0 6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG21740.1 - 2e-08 34.0 0.3 4.2e-07 29.7 0.2 2.2 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EKG21740.1 - 2.7e-05 24.3 0.1 5.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EKG21740.1 - 0.0004 19.3 0.1 0.00063 18.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EKG21740.1 - 0.00096 19.2 0.9 0.042 13.8 0.7 2.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_7 PF13241.1 EKG21740.1 - 0.0068 16.6 0.4 0.019 15.1 0.4 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding ADH_zinc_N PF00107.21 EKG21740.1 - 0.01 15.3 0.4 0.024 14.2 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EKG21740.1 - 0.02 14.3 0.2 0.21 11.0 0.0 2.4 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 EKG21740.1 - 0.04 14.3 0.6 0.74 10.2 0.4 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.5 EKG21740.1 - 0.091 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EKG21740.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tran_WecB PF03808.8 EKG21740.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family 6PF2K PF01591.13 EKG21743.1 - 3.2e-48 163.7 0.9 4.3e-48 163.2 0.6 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EKG21743.1 - 8.3e-31 107.2 0.0 1.6e-30 106.2 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Rxt3 PF08642.5 EKG21744.1 - 3.2e-20 72.5 0.0 6.6e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EKG21744.1 - 1e-05 25.3 0.0 0.00056 19.8 0.0 2.5 2 0 0 2 2 2 1 LCCL domain CLN3 PF02487.12 EKG21745.1 - 7e-101 337.9 12.2 5.8e-99 331.6 8.4 2.1 1 1 0 1 1 1 1 CLN3 protein zf-C2H2 PF00096.21 EKG21746.1 - 0.13 12.6 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Solute_trans_a PF03619.11 EKG21747.1 - 4.5e-63 213.1 13.2 5.2e-63 212.9 9.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha 7TM-7TMR_HD PF07698.6 EKG21747.1 - 2.1 7.7 13.5 0.18 11.2 2.9 2.5 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Glyco_tranf_2_3 PF13641.1 EKG21751.1 - 5.4e-30 104.8 0.1 7.6e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EKG21751.1 - 5.4e-21 75.1 0.3 5.4e-21 75.1 0.2 3.0 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EKG21751.1 - 6.6e-20 71.4 0.0 9.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EKG21751.1 - 3.4e-17 62.2 0.0 5.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EKG21751.1 - 1.1e-09 37.2 2.9 0.0002 19.8 1.8 2.2 2 0 0 2 2 2 2 Cellulose synthase Glyco_tranf_2_2 PF10111.4 EKG21751.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 UDPG_MGDP_dh_N PF03721.9 EKG21752.1 - 1.9e-48 164.3 0.1 7e-48 162.4 0.1 1.8 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EKG21752.1 - 1.2e-31 108.7 0.0 2.2e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EKG21752.1 - 1.8e-21 76.2 0.0 1.8e-17 63.4 0.0 3.0 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_23 PF13489.1 EKG21752.1 - 0.018 14.7 0.0 0.048 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain 3HCDH_N PF02737.13 EKG21752.1 - 0.092 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 EKG21753.1 - 3.8e-06 25.7 0.0 4.5e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_81 PF03639.8 EKG21755.1 - 2.8e-204 680.1 3.0 4.8e-204 679.3 2.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Glyco_hydro_18 PF00704.23 EKG21755.1 - 4.5e-16 59.2 0.8 2.2e-15 56.9 0.0 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 CsbD PF05532.7 EKG21755.1 - 0.31 10.7 0.2 0.68 9.6 0.1 1.5 1 0 0 1 1 1 0 CsbD-like DAO PF01266.19 EKG21757.1 - 2e-11 43.4 0.1 2.7e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG21757.1 - 9.5e-06 25.5 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EKG21757.1 - 0.00012 21.2 0.0 0.00014 21.0 0.0 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EKG21757.1 - 0.00061 19.5 0.0 0.00087 19.0 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EKG21757.1 - 0.0009 18.2 0.1 0.0011 17.9 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EKG21757.1 - 0.0023 17.9 0.0 0.0031 17.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EKG21757.1 - 0.0037 17.3 0.0 0.0047 17.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EKG21757.1 - 0.0073 15.1 0.1 0.0086 14.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EKG21757.1 - 0.02 14.7 0.1 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG21757.1 - 0.025 13.4 0.0 0.029 13.2 0.0 1.0 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Saccharop_dh PF03435.13 EKG21757.1 - 0.095 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase GIDA PF01134.17 EKG21757.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EKG21757.1 - 0.14 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain CAP_N PF01213.14 EKG21757.1 - 6.9 5.8 11.9 8.4 5.5 8.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HAD_2 PF13419.1 EKG21758.1 - 6.3e-23 81.8 0.0 7.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG21758.1 - 0.00011 22.7 0.0 0.00021 21.7 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase AA_permease PF00324.16 EKG21759.1 - 1e-18 66.9 13.0 1.2e-18 66.6 9.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EKG21760.1 - 0.0067 14.8 0.2 0.0077 14.6 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease alpha-hel2 PF14456.1 EKG21760.1 - 0.027 13.2 0.1 0.032 13.0 0.0 1.0 1 0 0 1 1 1 0 Alpha-helical domain 2 cobW PF02492.14 EKG21761.1 - 3.3e-33 114.6 0.0 4.1e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EKG21761.1 - 0.0002 20.2 0.1 0.34 9.6 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_23 PF13476.1 EKG21761.1 - 0.0072 16.6 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EKG21761.1 - 0.015 15.2 0.0 0.047 13.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EKG21761.1 - 0.062 13.6 0.0 0.12 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EKG21761.1 - 0.093 12.1 0.0 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EKG21761.1 - 0.094 13.5 0.4 0.19 12.5 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKG21761.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKG21761.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EKG21761.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.5 1 1 0 1 1 1 0 NACHT domain Hpt PF01627.18 EKG21762.1 - 1.6e-12 47.2 0.1 3e-12 46.3 0.1 1.5 1 0 0 1 1 1 1 Hpt domain Ribosomal_60s PF00428.14 EKG21762.1 - 0.036 14.4 0.5 0.089 13.1 0.3 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein AKAP7_NLS PF10469.4 EKG21763.1 - 2.6e-23 82.8 0.0 3.2e-22 79.2 0.0 2.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Lactonase PF10282.4 EKG21764.1 - 5.5e-70 236.1 0.0 7.2e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1586 PF07625.6 EKG21764.1 - 0.032 13.9 0.1 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) LIP PF03583.9 EKG21765.1 - 3.5e-71 239.7 0.2 4.8e-71 239.3 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase SKN1 PF03935.10 EKG21766.1 - 7.1e-227 753.4 4.6 8.4e-227 753.2 3.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TPR_1 PF00515.23 EKG21768.1 - 7.4e-53 174.1 29.6 7.9e-09 34.7 0.0 10.7 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EKG21768.1 - 4.9e-47 154.0 20.5 7.6e-07 28.5 0.0 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EKG21768.1 - 1.7e-45 152.5 20.6 1.4e-12 47.1 0.7 6.4 2 2 4 7 7 7 7 TPR repeat TPR_8 PF13181.1 EKG21768.1 - 9.4e-38 125.1 22.8 2.4e-07 30.0 0.0 10.2 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EKG21768.1 - 9.9e-32 108.7 18.9 1.6e-07 31.1 0.1 6.7 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EKG21768.1 - 2.1e-31 107.8 15.4 1.1e-08 35.4 0.1 7.1 6 1 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EKG21768.1 - 3e-29 98.7 18.1 1.7e-05 24.6 0.1 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 EKG21768.1 - 1.2e-23 83.2 16.0 4.8e-07 30.0 0.0 7.3 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKG21768.1 - 2.1e-22 77.5 20.5 9.6e-05 22.6 0.0 10.4 4 2 7 11 11 10 5 Tetratricopeptide repeat TPR_7 PF13176.1 EKG21768.1 - 8.4e-22 75.1 13.8 0.0014 18.3 0.0 9.6 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.1 EKG21768.1 - 8.6e-21 72.9 18.0 0.00037 20.7 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EKG21768.1 - 1.1e-13 50.7 10.9 0.00041 20.1 0.1 6.7 1 1 8 9 9 9 6 Tetratricopeptide repeat Apc3 PF12895.2 EKG21768.1 - 5.5e-13 48.8 13.0 1.4e-08 34.7 1.3 4.3 3 2 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EKG21768.1 - 3e-11 42.9 9.4 0.00034 19.7 1.2 4.6 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_21 PF09976.4 EKG21768.1 - 0.00021 21.2 12.1 0.12 12.2 1.5 4.6 4 2 1 5 5 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EKG21768.1 - 0.0037 17.0 0.6 32 4.4 0.0 4.6 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 EKG21768.1 - 0.0092 15.4 3.0 0.27 10.6 0.1 3.0 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 EKG21768.1 - 0.016 15.0 16.4 2.3 8.1 0.1 6.1 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EKG21768.1 - 0.031 14.2 13.8 7.5 6.6 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat GAS PF13851.1 EKG21768.1 - 0.14 11.3 0.7 0.33 10.1 0.5 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TPR_20 PF14561.1 EKG21768.1 - 0.15 12.1 11.1 0.38 10.9 0.0 5.5 5 2 2 7 7 6 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EKG21768.1 - 0.18 10.9 0.8 1.1 8.4 0.2 2.4 3 0 0 3 3 3 0 Coatomer epsilon subunit ChAPs PF09295.5 EKG21768.1 - 0.21 10.3 1.0 9.5 4.8 0.1 3.0 2 1 1 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 EKG21768.1 - 0.3 10.2 16.4 11 5.0 0.2 4.7 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP HALZ PF02183.13 EKG21769.1 - 9.1e-06 25.2 6.1 7.8e-05 22.3 0.6 2.5 1 1 1 2 2 2 2 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.1 EKG21769.1 - 3.3e-05 23.7 5.1 0.04 13.8 0.4 2.9 1 1 1 2 2 2 2 Centrosome localisation domain of PPC89 ADIP PF11559.3 EKG21769.1 - 0.00014 21.7 5.2 0.00014 21.7 3.6 2.4 3 0 0 3 3 2 1 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 EKG21769.1 - 0.00038 19.8 3.0 0.00038 19.8 2.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) ATG16 PF08614.6 EKG21769.1 - 0.001 18.9 6.6 0.001 18.9 4.6 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.7 EKG21769.1 - 0.0025 17.5 1.9 0.0025 17.5 1.3 3.0 3 0 0 3 3 3 1 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EKG21769.1 - 0.0034 17.1 5.1 0.0034 17.1 3.5 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 EKG21769.1 - 0.0042 17.0 3.9 0.78 9.7 0.5 3.0 1 1 1 2 2 2 2 bZIP transcription factor DivIC PF04977.10 EKG21769.1 - 0.0071 15.8 5.3 0.068 12.6 3.4 2.4 1 1 1 2 2 2 2 Septum formation initiator DUF3450 PF11932.3 EKG21769.1 - 0.01 15.1 3.0 0.01 15.1 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TSC22 PF01166.13 EKG21769.1 - 0.031 14.2 2.5 0.84 9.6 0.4 2.6 1 1 1 2 2 2 0 TSC-22/dip/bun family Reo_sigmaC PF04582.7 EKG21769.1 - 0.044 12.9 1.7 0.065 12.4 1.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_2 PF07716.10 EKG21769.1 - 0.087 12.6 4.4 0.62 9.9 1.2 2.9 1 1 3 4 4 4 0 Basic region leucine zipper Shugoshin_N PF07558.6 EKG21769.1 - 0.13 12.0 3.3 0.32 10.7 1.9 2.0 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.1 EKG21769.1 - 0.29 10.8 6.4 2.8 7.7 0.5 3.1 2 1 1 3 3 3 0 Sperm tail C-terminal domain IncA PF04156.9 EKG21769.1 - 3.3 7.2 15.7 0.12 11.9 5.9 2.3 2 1 0 2 2 2 0 IncA protein DivIVA PF05103.8 EKG21769.1 - 4.8 7.2 13.2 7 6.7 2.6 3.1 2 1 0 2 2 2 0 DivIVA protein Atg14 PF10186.4 EKG21769.1 - 5 5.9 12.2 0.03 13.2 2.5 1.8 2 0 0 2 2 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EKG21769.1 - 9.5 6.6 14.4 0.43 10.9 2.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Chorismate_bind PF00425.13 EKG21770.1 - 3.4e-89 298.5 0.0 5.1e-89 297.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EKG21770.1 - 4.3e-31 107.7 0.0 2e-26 92.6 0.0 3.6 3 0 0 3 3 3 3 Anthranilate synthase component I, N terminal region CFEM PF05730.6 EKG21771.1 - 4.7e-15 55.1 5.5 1.6e-14 53.4 3.8 1.9 1 0 0 1 1 1 1 CFEM domain CtaG_Cox11 PF04442.9 EKG21772.1 - 2.4e-57 192.9 0.0 3e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF2479 PF10651.4 EKG21772.1 - 0.14 11.6 0.1 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2479) ADH_zinc_N PF00107.21 EKG21773.1 - 9.1e-14 51.1 0.1 1.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG21773.1 - 2.8e-09 37.9 0.0 8.5e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG21773.1 - 1.4e-06 28.0 0.2 4.3e-06 26.4 0.1 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Arginase PF00491.16 EKG21776.1 - 6.7e-90 301.1 0.0 8.8e-90 300.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EKG21776.1 - 0.051 13.7 0.1 0.12 12.6 0.0 1.7 1 1 1 2 2 2 0 UPF0489 domain MatE PF01554.13 EKG21777.1 - 1.1e-22 80.3 2.9 1.3e-22 80.1 2.0 1.1 1 0 0 1 1 1 1 MatE MFS_1 PF07690.11 EKG21778.1 - 2.5e-30 105.4 19.9 3.1e-30 105.0 13.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21778.1 - 3.4e-11 42.3 12.4 4.9e-11 41.8 8.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.10 EKG21778.1 - 0.00036 19.3 2.6 0.042 12.5 0.4 2.2 2 0 0 2 2 2 2 PUCC protein OATP PF03137.15 EKG21778.1 - 0.073 11.1 2.6 1.6 6.6 0.1 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EKG21779.1 - 1.7e-07 30.2 26.6 1.7e-07 30.2 18.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EKG21780.1 - 4.5e-55 186.8 0.6 1e-54 185.6 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG21780.1 - 3.4e-07 30.0 8.2 6.5e-07 29.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.19 EKG21781.1 - 5.2e-09 35.4 0.1 6.6e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase adh_short PF00106.20 EKG21782.1 - 0.0044 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG21782.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase p450 PF00067.17 EKG21784.1 - 1e-50 172.6 0.0 3.6e-44 151.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 ABC2_membrane PF01061.19 EKG21785.1 - 2.1e-39 134.8 20.6 3.2e-39 134.2 14.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EKG21785.1 - 3.3e-19 69.5 0.0 5.5e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EKG21785.1 - 1.9e-06 27.4 0.4 8e-06 25.3 0.2 1.9 2 0 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.2 EKG21785.1 - 1.5e-05 23.9 0.4 6.1e-05 22.0 0.0 2.0 1 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EKG21785.1 - 2.2e-05 23.6 0.1 3.8e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PDR_CDR PF06422.7 EKG21785.1 - 0.00025 20.6 3.0 0.00077 19.0 0.1 3.0 3 1 1 4 4 4 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EKG21785.1 - 0.00035 19.7 3.9 0.00035 19.7 2.7 1.5 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 EKG21785.1 - 0.0014 18.6 0.4 0.0034 17.3 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EKG21785.1 - 0.0028 17.1 0.1 0.0028 17.1 0.1 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain cobW PF02492.14 EKG21785.1 - 0.0036 16.7 0.1 0.0058 16.0 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EKG21785.1 - 0.013 15.6 0.4 0.061 13.4 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EKG21785.1 - 0.025 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EKG21785.1 - 0.026 14.4 0.1 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EKG21785.1 - 0.039 13.6 0.0 0.089 12.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EKG21785.1 - 0.05 13.5 0.3 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EKG21785.1 - 0.077 12.6 0.3 0.15 11.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EKG21785.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EKG21785.1 - 0.17 12.6 0.0 0.4 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EKG21785.1 - 0.26 11.1 0.0 1.3 8.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF962 PF06127.6 EKG21785.1 - 2.8 7.8 5.9 0.73 9.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF962) p450 PF00067.17 EKG21786.1 - 3e-61 207.3 0.0 3.5e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG21787.1 - 0.048 12.1 0.0 0.062 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Methyltransf_2 PF00891.13 EKG21788.1 - 1e-30 106.7 0.0 1.4e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EKG21788.1 - 1.2e-06 29.0 0.0 4e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG21788.1 - 0.095 13.1 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EKG21789.1 - 2.8e-26 92.0 38.8 3.4e-26 91.7 26.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3505 PF12013.3 EKG21790.1 - 0.043 14.0 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) MS_channel PF00924.13 EKG21791.1 - 7.8e-22 77.6 0.9 1.3e-21 76.8 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EKG21791.1 - 0.00027 19.9 0.2 0.00072 18.6 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EKG21791.1 - 0.00033 19.8 0.0 0.0011 18.2 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EKG21791.1 - 0.00066 19.7 0.2 0.0023 18.0 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EKG21791.1 - 0.0011 18.6 0.0 0.0069 16.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain SMP PF04927.7 EKG21792.1 - 6.5e-06 26.0 4.4 0.008 16.1 0.5 3.4 2 1 1 3 3 3 2 Seed maturation protein Tubulin PF00091.20 EKG21793.1 - 6.2e-65 219.0 0.0 8.1e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EKG21793.1 - 1e-43 148.4 0.0 1.5e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EKG21793.1 - 0.0002 20.8 0.0 0.00037 20.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain GMC_oxred_N PF00732.14 EKG21795.1 - 2.1e-29 102.6 0.0 2.2e-25 89.4 0.0 2.9 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG21795.1 - 3.9e-26 92.0 0.1 7e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EKG21795.1 - 0.00089 19.2 0.1 0.0027 17.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG21795.1 - 0.0032 16.3 0.2 0.0067 15.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EKG21795.1 - 0.0051 15.7 0.2 0.26 10.1 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG21795.1 - 0.046 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG21795.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Abhydrolase_3 PF07859.8 EKG21797.1 - 3.2e-17 62.8 0.0 5.6e-17 62.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG21797.1 - 4.3e-10 39.5 0.0 5.9e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG21797.1 - 5.2e-10 38.9 0.0 6.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 EKG21797.1 - 2.6e-07 29.7 0.0 3.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EKG21797.1 - 6e-07 28.6 0.0 8.2e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EKG21797.1 - 5.4e-06 26.4 0.4 2.1e-05 24.5 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EKG21797.1 - 7.3e-05 21.6 0.0 0.00032 19.5 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EKG21797.1 - 0.0015 18.0 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EKG21797.1 - 0.0058 16.0 0.4 0.51 9.7 0.0 2.4 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EKG21797.1 - 0.0087 15.6 0.1 1.4 8.3 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold WD40 PF00400.27 EKG21799.1 - 1.2e-18 66.1 6.6 5.9e-07 29.1 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 EKG21800.1 - 6e-23 80.6 0.1 7e-23 80.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase E chain DUF3433 PF11915.3 EKG21802.1 - 1.2e-21 76.6 3.4 1.2e-21 76.6 2.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Peptidase_S8 PF00082.17 EKG21803.1 - 8e-43 146.5 11.9 1.3e-42 145.9 8.3 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EKG21803.1 - 0.00059 20.3 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glutaredoxin PF00462.19 EKG21804.1 - 2.6e-20 72.1 0.0 7.9e-19 67.4 0.0 2.6 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EKG21804.1 - 7.9e-17 60.8 0.0 1.8e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EKG21804.1 - 8.4e-05 22.6 0.0 0.00085 19.3 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EKG21804.1 - 0.019 15.1 0.3 0.41 10.8 0.0 2.8 2 2 1 3 3 3 0 Thioredoxin-like domain TrbC_Ftype PF09673.5 EKG21804.1 - 0.045 13.3 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein ArsC PF03960.10 EKG21804.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 ArsC family Thioredoxin_3 PF13192.1 EKG21804.1 - 0.14 12.0 0.1 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain Brix PF04427.13 EKG21806.1 - 6.2e-25 87.9 0.2 9.9e-25 87.3 0.2 1.3 1 0 0 1 1 1 1 Brix domain THF_DHG_CYH PF00763.18 EKG21807.1 - 8.9e-18 64.4 0.0 1.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EKG21807.1 - 6.3e-13 48.1 0.0 3.3e-09 36.0 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MMS19_N PF14500.1 EKG21808.1 - 9.8e-88 293.8 0.1 2.5e-86 289.1 0.0 3.0 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EKG21808.1 - 2.5e-86 290.0 9.9 3.9e-86 289.3 3.4 2.8 2 1 0 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EKG21808.1 - 1.6e-05 25.0 17.3 0.0028 17.8 0.1 7.1 6 2 2 8 8 8 3 HEAT repeats APH_6_hur PF04655.9 EKG21808.1 - 0.05 12.7 0.5 3 6.9 0.1 2.5 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Adaptin_N PF01602.15 EKG21808.1 - 0.14 10.4 5.1 10 4.3 0.1 4.3 4 3 1 5 5 5 0 Adaptin N terminal region HEAT_EZ PF13513.1 EKG21808.1 - 0.4 11.2 29.6 0.05 14.1 0.6 8.3 9 1 2 11 11 11 0 HEAT-like repeat ADH_N PF08240.7 EKG21809.1 - 6.1e-26 90.3 2.3 1.2e-25 89.4 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG21809.1 - 1.3e-16 60.3 0.0 2e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG21809.1 - 5.8e-06 27.2 0.0 1.1e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 EKG21809.1 - 0.00083 19.4 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EKG21809.1 - 0.0014 17.8 0.1 0.0023 17.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Vezatin PF12632.2 EKG21810.1 - 1.8e-49 168.1 0.0 2.9e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Polysacc_synt_C PF14667.1 EKG21810.1 - 0.26 11.0 1.2 0.45 10.3 0.8 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Nro1 PF12753.2 EKG21811.1 - 0.0045 15.9 0.2 0.0056 15.6 0.2 1.1 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 TPR_11 PF13414.1 EKG21811.1 - 0.099 12.3 4.8 2.2 8.0 1.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.1 EKG21811.1 - 0.26 11.2 6.1 0.43 10.5 2.5 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Rab5ip PF07019.7 EKG21812.1 - 3.7e-21 75.0 3.5 4.5e-21 74.7 2.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) FtsX PF02687.16 EKG21812.1 - 0.045 13.5 2.0 0.05 13.3 1.4 1.1 1 0 0 1 1 1 0 FtsX-like permease family Fungal_trans PF04082.13 EKG21814.1 - 8.5e-18 64.1 0.0 1.6e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSBP1 PF06825.7 EKG21814.1 - 0.092 12.3 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 2OG-FeII_Oxy_2 PF13532.1 EKG21815.1 - 8.2e-30 104.0 0.0 1.2e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EKG21815.1 - 0.0007 19.8 0.0 0.0016 18.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HSCB_C PF07743.8 EKG21816.1 - 1.6e-17 63.7 10.9 1.6e-17 63.7 7.6 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EKG21816.1 - 7.2e-08 32.0 0.0 2.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain COP23 PF14218.1 EKG21816.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Macoilin PF09726.4 EKG21817.1 - 0.0015 16.9 0.1 0.0015 16.9 0.0 2.4 2 0 0 2 2 2 1 Transmembrane protein Spc7 PF08317.6 EKG21817.1 - 0.14 10.7 0.1 0.35 9.4 0.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EKG21817.1 - 0.14 12.4 0.7 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein F-box PF00646.28 EKG21819.1 - 0.0024 17.4 0.0 0.0065 16.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EKG21819.1 - 0.013 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like SH3_9 PF14604.1 EKG21820.1 - 7.5e-32 108.6 2.0 1e-15 56.9 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EKG21820.1 - 2.3e-28 97.3 3.8 2.8e-14 52.2 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EKG21820.1 - 3.3e-16 58.5 0.0 2.8e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EKG21820.1 - 3.1e-08 33.5 0.0 4.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Extensin_2 PF04554.8 EKG21821.1 - 0.095 12.5 15.9 0.12 12.2 11.1 1.1 1 0 0 1 1 1 0 Extensin-like region STT3 PF02516.9 EKG21822.1 - 2.2e-129 432.5 40.3 2.4e-124 415.9 26.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit dCMP_cyt_deam_1 PF00383.17 EKG21823.1 - 0.21 11.2 0.9 2.1 8.0 0.7 2.2 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Ctr PF04145.10 EKG21825.1 - 1.6e-20 73.6 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family EpuA PF11772.3 EKG21825.1 - 0.05 13.0 0.3 0.09 12.2 0.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Hexapep PF00132.19 EKG21826.1 - 7.6e-15 53.6 11.4 6.1e-10 38.1 0.7 3.7 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EKG21826.1 - 1.7e-09 37.5 0.1 3.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EKG21826.1 - 1.8e-09 36.9 11.1 1e-05 25.0 1.0 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 EKG21826.1 - 7.3e-09 35.3 8.7 1.2e-08 34.6 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.16 EKG21827.1 - 0.001 18.4 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EKG21828.1 - 3e-30 105.3 1.5 4.6e-30 104.7 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG21828.1 - 1.4e-24 87.1 0.2 1.7e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG21828.1 - 1.1e-14 54.5 0.9 1.6e-14 53.9 0.6 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG21828.1 - 0.01 15.2 0.2 0.085 12.2 0.1 2.4 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EKG21828.1 - 0.013 15.2 0.8 0.042 13.6 0.2 2.1 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CbiD PF01888.12 EKG21828.1 - 0.015 14.2 0.1 0.032 13.1 0.1 1.5 1 0 0 1 1 1 0 CbiD Polysacc_synt_2 PF02719.10 EKG21828.1 - 0.029 13.2 0.0 0.049 12.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EKG21828.1 - 0.08 12.0 0.0 0.19 10.8 0.0 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DENN PF02141.16 EKG21829.1 - 7.2e-56 188.8 0.0 1.2e-55 188.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EKG21829.1 - 1.8e-19 69.4 0.0 4.4e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EKG21829.1 - 5.8e-19 67.9 1.3 1.2e-18 66.9 0.9 1.6 1 0 0 1 1 1 1 dDENN domain C1_3 PF07649.7 EKG21829.1 - 0.002 18.1 3.1 0.0038 17.2 2.1 1.5 1 0 0 1 1 1 1 C1-like domain C1_2 PF03107.11 EKG21829.1 - 0.02 14.9 4.4 0.042 13.9 3.0 1.5 1 0 0 1 1 1 0 C1 domain C1_1 PF00130.17 EKG21829.1 - 1 9.1 10.4 2 8.2 7.2 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF974 PF06159.8 EKG21830.1 - 7.8e-61 205.6 0.0 9.3e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) THEG PF14912.1 EKG21830.1 - 0.048 14.1 0.2 0.096 13.2 0.1 1.4 1 0 0 1 1 1 0 Testicular haploid expressed repeat SET PF00856.23 EKG21831.1 - 1.1e-11 45.2 0.0 1.6e-07 31.7 0.0 2.1 1 1 1 2 2 2 2 SET domain DUF466 PF04328.8 EKG21831.1 - 0.031 14.0 0.2 0.054 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF466) DUF2408 PF10303.4 EKG21832.1 - 8e-46 155.4 14.7 5.4e-24 84.8 2.5 5.8 3 3 2 5 5 5 4 Protein of unknown function (DUF2408) Cob_adeno_trans PF01923.13 EKG21832.1 - 0.0038 17.0 3.6 0.34 10.7 0.1 3.0 3 0 0 3 3 3 2 Cobalamin adenosyltransferase DUF1664 PF07889.7 EKG21832.1 - 0.063 13.0 1.0 0.72 9.6 0.1 3.0 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF1662 PF07878.6 EKG21832.1 - 0.23 11.2 2.2 2 8.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1662) Laminin_II PF06009.7 EKG21832.1 - 0.35 10.6 8.7 0.14 11.9 0.9 3.1 4 0 0 4 4 4 0 Laminin Domain II DUF1640 PF07798.6 EKG21832.1 - 1.7 8.6 9.8 0.32 11.0 3.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) Ribosomal_60s PF00428.14 EKG21833.1 - 3.2e-25 88.3 11.4 4e-25 88.0 7.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Acetyltransf_1 PF00583.19 EKG21834.1 - 2.5e-14 53.0 0.2 2.3e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKG21834.1 - 2.1e-07 30.5 0.1 3.5e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EKG21834.1 - 1.5e-05 25.1 0.0 0.00085 19.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG21834.1 - 0.00088 19.3 0.0 0.0026 17.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EKG21834.1 - 0.0028 17.5 0.1 0.0065 16.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EKG21834.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Alba PF01918.16 EKG21835.1 - 0.00066 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Alba Protoglobin PF11563.3 EKG21836.1 - 7.9e-60 201.0 0.2 9.4e-60 200.8 0.1 1.1 1 0 0 1 1 1 1 Protoglobin SKG6 PF08693.5 EKG21837.1 - 0.015 14.6 0.4 0.028 13.7 0.3 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mitofilin PF09731.4 EKG21838.1 - 0.38 9.3 5.3 0.47 9.0 3.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PQ-loop PF04193.9 EKG21839.1 - 1.3e-40 136.7 8.5 3.9e-21 74.3 0.1 3.1 2 1 1 3 3 3 2 PQ loop repeat DUF2244 PF10003.4 EKG21839.1 - 0.029 13.7 0.2 0.029 13.7 0.1 1.9 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3278 PF11683.3 EKG21839.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) Aminotran_4 PF01063.14 EKG21840.1 - 7.1e-20 71.4 0.0 1.7e-19 70.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class IV Retrotrans_gag PF03732.12 EKG21841.1 - 3.5e-07 30.2 0.6 3.5e-07 30.2 0.4 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF972 PF06156.8 EKG21841.1 - 0.0011 19.2 0.2 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF972) DivIC PF04977.10 EKG21841.1 - 0.041 13.3 1.4 0.064 12.7 0.4 1.6 2 0 0 2 2 2 0 Septum formation initiator ALIX_LYPXL_bnd PF13949.1 EKG21841.1 - 0.057 12.3 0.0 0.53 9.2 0.0 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4618 PF15397.1 EKG21841.1 - 0.065 12.5 0.8 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) PspA_IM30 PF04012.7 EKG21841.1 - 0.1 11.9 0.2 0.1 11.9 0.1 1.5 2 0 0 2 2 2 0 PspA/IM30 family bZIP_2 PF07716.10 EKG21841.1 - 0.3 10.9 2.0 0.63 9.8 1.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EKG21841.1 - 0.39 10.2 3.7 0.73 9.3 0.8 2.0 2 0 0 2 2 2 0 IncA protein Fib_alpha PF08702.5 EKG21841.1 - 0.52 10.4 2.4 1.7 8.7 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RNA_pol_3_Rpc31 PF11705.3 EKG21842.1 - 0.1 12.5 2.2 0.13 12.2 1.5 1.2 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 IKI3 PF04762.7 EKG21843.1 - 0 1090.1 0.0 0 1089.8 0.0 1.0 1 0 0 1 1 1 1 IKI3 family COX7C PF02935.11 EKG21843.1 - 1.3e-11 44.1 0.5 2.6e-11 43.1 0.3 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 EKG21844.1 - 5.1e-110 366.8 0.1 8.6e-110 366.1 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EKG21844.1 - 9.5e-64 213.9 0.6 9.5e-64 213.9 0.4 2.2 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EKG21844.1 - 1.4e-20 73.4 0.3 3.6e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG21844.1 - 1.9e-07 30.8 0.0 4.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG21844.1 - 0.0018 18.1 0.0 0.02 14.7 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Prp19 PF08606.6 EKG21844.1 - 0.0064 16.1 0.6 3.1 7.6 0.0 3.1 3 0 0 3 3 3 2 Prp19/Pso4-like T2SE PF00437.15 EKG21844.1 - 0.014 14.3 0.0 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rabaptin PF03528.10 EKG21844.1 - 0.031 14.2 0.7 0.13 12.1 0.5 2.1 1 0 0 1 1 1 0 Rabaptin AAA_19 PF13245.1 EKG21844.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Cut8_C PF08559.5 EKG21845.1 - 3.5e-47 159.8 0.0 4.7e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EKG21845.1 - 5.5e-11 42.0 0.1 5.5e-11 42.0 0.1 1.9 2 0 0 2 2 2 1 Cut8 dimerisation domain Cut8_N PF14482.1 EKG21845.1 - 4.3e-06 26.6 7.7 8.6e-06 25.6 5.3 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain AP_endonuc_2 PF01261.19 EKG21845.1 - 0.0073 15.6 0.0 0.62 9.3 0.0 2.9 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel Thiolase_C PF02803.13 EKG21846.1 - 8.2e-12 44.6 0.4 1.7e-10 40.3 0.0 2.9 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EKG21846.1 - 4.6e-05 22.9 0.0 0.0096 15.5 0.0 2.6 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EKG21846.1 - 9.2e-05 21.5 0.0 0.0011 17.9 0.0 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EKG21846.1 - 0.0014 18.1 0.1 0.0049 16.3 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EKG21846.1 - 0.013 15.3 1.2 0.69 9.7 0.0 3.4 4 0 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 EKG21846.1 - 0.038 12.4 0.1 0.24 9.8 0.1 2.0 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Tcp11 PF05794.8 EKG21847.1 - 1.1e-89 301.2 0.0 1.4e-89 300.8 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Glycos_transf_1 PF00534.15 EKG21848.1 - 2.1e-19 69.6 0.0 3.6e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EKG21848.1 - 1.3e-07 31.8 0.0 3.5e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 60KD_IMP PF02096.15 EKG21849.1 - 6.8e-15 55.2 0.0 8.8e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein RGS PF00615.14 EKG21850.1 - 7.2e-32 109.9 0.1 3e-31 107.9 0.0 2.1 2 1 1 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EKG21850.1 - 1.5e-22 79.1 0.2 3.6e-17 61.8 0.0 3.1 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.20 EKG21851.1 - 8.4e-59 198.8 0.0 1.1e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21851.1 - 1.3e-26 93.2 0.0 1.9e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG21851.1 - 2.3e-12 46.4 0.0 3.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG21851.1 - 0.032 13.3 0.0 0.09 11.8 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family JAB PF01398.16 EKG21852.1 - 4.3e-18 65.1 0.1 9.2e-18 64.0 0.0 1.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EKG21852.1 - 5.5e-18 65.1 0.4 8.5e-18 64.5 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EKG21852.1 - 0.031 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EKG21853.1 - 2.5e-163 543.5 0.0 3e-163 543.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) NIF PF03031.13 EKG21854.1 - 1.2e-41 142.0 0.0 1.9e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CENP-C_mid PF15620.1 EKG21854.1 - 0.015 15.0 6.3 0.022 14.4 4.4 1.2 1 0 0 1 1 1 0 Centromere assembly component CENP-C middle DNMT3B-binding region DUF601 PF04642.7 EKG21854.1 - 2 7.6 10.5 3.5 6.9 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 IF-2B PF01008.12 EKG21855.1 - 2.1e-60 204.0 6.0 7.6e-35 120.2 0.4 2.9 2 1 0 2 2 2 2 Initiation factor 2 subunit family Pre-SET PF05033.11 EKG21856.1 - 0.98 9.7 6.9 4.6 7.5 4.1 2.2 1 1 0 1 1 1 0 Pre-SET motif SCRL PF06876.7 EKG21856.1 - 2.8 7.9 8.4 5.1 7.1 1.3 2.5 1 1 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Pkinase PF00069.20 EKG21857.1 - 3.9e-36 124.5 0.0 5.2e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21857.1 - 2.1e-14 53.2 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG21857.1 - 0.017 14.8 0.0 0.56 9.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nucleoporin_C PF03177.9 EKG21858.1 - 1.3e-79 268.2 2.9 1.7e-79 267.9 2.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EKG21858.1 - 5.9e-50 170.2 0.0 1.2e-49 169.1 0.0 1.5 2 0 0 2 2 2 1 Nup133 N terminal like CIAPIN1 PF05093.8 EKG21859.1 - 6.7e-35 119.1 3.5 1.1e-34 118.5 2.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis HABP4_PAI-RBP1 PF04774.10 EKG21860.1 - 0.00047 20.6 6.2 0.0021 18.5 4.3 2.0 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family He_PIG PF05345.7 EKG21862.1 - 4.8e-17 61.7 11.7 3.4e-05 23.7 0.0 4.8 4 0 0 4 4 4 4 Putative Ig domain SKG6 PF08693.5 EKG21862.1 - 0.00031 19.9 3.7 0.00063 19.0 2.6 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EKG21862.1 - 0.0066 14.7 0.0 0.01 14.1 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rifin_STEVOR PF02009.11 EKG21862.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family DUF912 PF06024.7 EKG21862.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 EKG21862.1 - 0.014 14.8 0.0 0.032 13.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) ETRAMP PF09716.5 EKG21862.1 - 0.031 14.2 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_US9 PF06072.6 EKG21862.1 - 0.067 13.0 0.5 0.16 11.7 0.4 1.6 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 m04gp34like PF12216.3 EKG21862.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein Plasmodium_Vir PF05795.6 EKG21862.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_M56 PF05569.6 EKG21862.1 - 0.23 10.4 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3404 PF11884.3 EKG21862.1 - 0.26 10.1 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Pyr_redox_2 PF07992.9 EKG21863.1 - 4.1e-36 124.7 1.5 7.3e-36 123.9 1.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EKG21863.1 - 3.5e-34 117.1 1.8 4e-34 116.9 0.2 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EKG21863.1 - 1e-16 61.0 2.6 1.8e-16 60.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG21863.1 - 1.1e-07 32.1 0.1 8.9e-07 29.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EKG21863.1 - 5.8e-06 25.4 0.0 0.0004 19.4 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EKG21863.1 - 0.043 12.7 0.2 0.043 12.7 0.1 2.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EKG21863.1 - 0.082 12.4 0.5 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EKG21863.1 - 0.12 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG21863.1 - 0.13 10.7 1.6 13 4.0 0.3 3.1 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 EKG21863.1 - 0.21 10.4 2.0 1.2 7.9 0.8 2.4 3 0 0 3 3 3 0 FAD binding domain UPF0118 PF01594.11 EKG21867.1 - 0.17 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 CDC45 PF02724.9 EKG21867.1 - 0.18 9.7 4.0 0.22 9.4 2.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Caldesmon PF02029.10 EKG21867.1 - 0.19 10.1 17.2 0.27 9.6 11.9 1.1 1 0 0 1 1 1 0 Caldesmon Borrelia_P83 PF05262.6 EKG21867.1 - 0.3 9.3 9.8 0.42 8.8 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S64 PF08192.6 EKG21867.1 - 0.62 8.3 1.9 0.93 7.7 1.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.5 EKG21867.1 - 1.3 7.3 7.2 2.1 6.6 5.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MIP-T3 PF10243.4 EKG21867.1 - 6.2 5.1 21.9 9.4 4.5 15.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAF1 PF04857.15 EKG21868.1 - 2.2e-48 164.8 0.0 2.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease bZIP_1 PF00170.16 EKG21870.1 - 6.7e-09 35.5 10.1 1.2e-08 34.7 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EKG21870.1 - 1.6e-05 24.5 10.0 1.6e-05 24.5 6.9 1.9 1 1 1 2 2 2 1 Basic region leucine zipper Mitofilin PF09731.4 EKG21870.1 - 0.0049 15.6 5.5 0.0054 15.4 3.8 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein SOBP PF15279.1 EKG21870.1 - 0.016 15.5 11.1 0.022 15.1 7.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 EKG21870.1 - 0.019 13.2 11.0 0.021 13.1 7.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4618 PF15397.1 EKG21870.1 - 0.12 11.7 6.6 0.18 11.1 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF342 PF03961.8 EKG21870.1 - 0.35 9.2 3.0 0.43 8.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EKG21870.1 - 0.66 9.6 9.3 1 8.9 6.5 1.3 1 0 0 1 1 1 0 Mnd1 family Ndc1_Nup PF09531.5 EKG21870.1 - 2.5 6.4 6.5 3 6.1 4.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CytochromB561_N PF09786.4 EKG21870.1 - 7 4.9 14.0 0.58 8.5 6.4 1.5 2 0 0 2 2 2 0 Cytochrome B561, N terminal DDHD PF02862.12 EKG21870.1 - 8.5 6.1 10.6 15 5.2 7.3 1.4 1 0 0 1 1 1 0 DDHD domain Metallophos_2 PF12850.2 EKG21871.1 - 1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.14 EKG21872.1 - 1.8e-29 102.6 0.0 2.3e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EKG21872.1 - 1.1e-06 27.2 0.0 1.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EKG21872.1 - 6.7e-06 25.2 0.0 9.6e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.14 EKG21872.1 - 0.00017 21.4 0.1 0.00064 19.5 0.0 1.9 2 1 1 3 3 3 1 B12 binding domain Interferon PF00143.14 EKG21873.1 - 0.11 12.2 0.2 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Interferon alpha/beta domain UCH PF00443.24 EKG21874.1 - 8.3e-74 248.0 0.0 1.2e-72 244.2 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EKG21874.1 - 4.3e-15 55.9 0.0 1.3e-14 54.3 0.0 2.0 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.1 EKG21874.1 - 8.7e-14 51.6 0.0 5.2e-06 26.1 0.0 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 EKG21874.1 - 0.016 14.6 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific protease C-terminal HJURP_mid PF12346.3 EKG21874.1 - 0.019 15.1 0.8 1.3 9.1 0.1 2.6 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat DUF726 PF05277.7 EKG21875.1 - 1.4e-115 385.8 3.5 2.1e-113 378.7 4.1 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF726) Thioesterase PF00975.15 EKG21875.1 - 9.6e-05 22.7 0.4 0.00028 21.1 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EKG21875.1 - 0.0013 18.6 0.6 0.0037 17.1 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG21875.1 - 0.024 14.3 0.9 0.05 13.3 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family DUF900 PF05990.7 EKG21875.1 - 0.041 13.2 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.17 EKG21875.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase ICE2 PF08426.5 EKG21876.1 - 5.3e-145 483.1 5.5 6.2e-145 482.9 3.8 1.0 1 0 0 1 1 1 1 ICE2 UPF0160 PF03690.8 EKG21877.1 - 1.1e-121 406.0 0.0 1.3e-121 405.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) adh_short PF00106.20 EKG21878.1 - 6.9e-22 78.1 0.1 2.4e-21 76.3 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG21878.1 - 7.7e-20 71.6 0.1 1.7e-19 70.5 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG21878.1 - 2.4e-11 43.6 0.5 1.9e-09 37.4 0.3 2.3 1 1 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EKG21878.1 - 0.0047 17.3 0.1 0.016 15.6 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.21 EKG21878.1 - 0.0071 15.8 0.2 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EKG21878.1 - 0.024 13.1 0.2 0.058 11.8 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF3704 PF12488.3 EKG21878.1 - 0.03 13.9 2.1 0.061 12.9 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) AlaDh_PNT_C PF01262.16 EKG21878.1 - 0.06 12.9 0.0 0.27 10.7 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EKG21878.1 - 0.061 12.7 0.0 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EKG21878.1 - 0.072 13.0 0.2 0.18 11.8 0.0 1.8 2 1 0 2 2 2 0 NADH(P)-binding DUF3789 PF12664.2 EKG21878.1 - 0.096 12.0 1.4 0.28 10.5 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) Pkinase PF00069.20 EKG21879.1 - 5.1e-72 242.1 0.0 1.2e-71 240.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG21879.1 - 1.6e-51 174.8 0.0 2.8e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG21879.1 - 0.0018 17.3 0.0 0.01 14.8 0.0 2.1 3 0 0 3 3 3 1 Kinase-like E3_UbLigase_R4 PF13764.1 EKG21879.1 - 0.84 7.4 3.9 0.2 9.5 0.1 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 RasGEF PF00617.14 EKG21881.1 - 2.1e-57 193.8 0.1 4.4e-57 192.8 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EKG21881.1 - 3.8e-17 62.2 0.0 1.4e-16 60.4 0.0 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EKG21881.1 - 6.9e-05 22.3 0.0 0.00016 21.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG21881.1 - 0.00024 20.4 0.0 0.0005 19.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EKG21881.1 - 0.033 13.6 0.0 0.067 12.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain PPR_2 PF13041.1 EKG21882.1 - 1.4e-22 79.4 0.0 1.3e-11 44.2 0.0 5.0 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 EKG21882.1 - 1.1e-16 59.5 0.0 0.059 13.6 0.0 7.3 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.15 EKG21882.1 - 2.7e-13 48.9 0.4 0.00057 19.6 0.0 6.4 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 EKG21882.1 - 9.6e-10 37.7 0.0 0.012 15.0 0.0 4.4 4 0 0 4 4 4 2 PPR repeat TPR_15 PF13429.1 EKG21882.1 - 0.0046 16.0 0.4 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EKG21882.1 - 0.088 12.7 0.0 0.5 10.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat cwf18 PF08315.7 EKG21883.1 - 2.4e-41 141.2 8.9 2.4e-41 141.2 6.2 1.6 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.2 EKG21884.1 - 1e-15 57.9 2.2 1e-15 57.9 1.5 3.0 2 0 0 2 2 2 1 SUZ domain R3H PF01424.17 EKG21884.1 - 1.5e-07 30.9 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain Ribosomal_L3 PF00297.17 EKG21885.1 - 1.1e-10 41.3 1.7 1.3e-10 41.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 zf-RING_2 PF13639.1 EKG21886.1 - 1.7e-07 30.9 12.7 2.7e-07 30.3 8.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EKG21886.1 - 0.00023 20.9 3.8 0.00034 20.4 2.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EKG21886.1 - 0.00038 19.9 13.8 0.00058 19.3 9.6 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EKG21886.1 - 0.0013 18.8 5.2 0.002 18.1 3.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EKG21886.1 - 0.0038 16.9 13.6 0.006 16.2 9.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain C1_1 PF00130.17 EKG21886.1 - 0.014 15.1 3.7 0.014 15.1 2.6 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EKG21886.1 - 0.025 14.5 13.9 0.044 13.8 9.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG21886.1 - 0.06 13.0 9.4 0.092 12.4 6.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EKG21886.1 - 0.11 12.4 13.0 0.45 10.5 9.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.20 EKG21886.1 - 0.78 9.4 13.9 1.4 8.5 9.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EKG21886.1 - 9.3 6.3 13.0 16 5.6 9.0 1.4 1 0 0 1 1 1 0 RING-variant domain SUR7 PF06687.7 EKG21887.1 - 1.3e-37 129.4 18.1 1.5e-37 129.2 12.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family RCR PF12273.3 EKG21887.1 - 0.21 12.1 2.8 0.37 11.3 0.0 2.5 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Ydc2-catalyt PF09159.5 EKG21889.1 - 4.6e-63 213.2 0.4 8.4e-63 212.4 0.3 1.4 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 EKG21889.1 - 0.00036 19.9 0.0 0.00077 18.9 0.0 1.6 1 0 0 1 1 1 1 SAP domain Pox_A22 PF04848.8 EKG21889.1 - 0.00091 19.1 0.1 3.6 7.4 0.0 3.2 3 0 0 3 3 3 2 Poxvirus A22 protein Pkinase PF00069.20 EKG21890.1 - 0.0063 15.6 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Sec61_beta PF03911.11 EKG21892.1 - 3.4e-20 71.5 1.1 4.4e-20 71.1 0.8 1.2 1 0 0 1 1 1 1 Sec61beta family Fea1 PF07692.6 EKG21893.1 - 0.24 10.1 0.6 0.43 9.3 0.5 1.3 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein MARVEL PF01284.18 EKG21894.1 - 1.4e-27 96.2 1.2 1.8e-27 95.9 0.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain IncA PF04156.9 EKG21894.1 - 0.0084 15.7 0.9 0.0084 15.7 0.6 2.0 3 0 0 3 3 3 1 IncA protein LexA_DNA_bind PF01726.11 EKG21894.1 - 0.14 11.7 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain 7TM-7TMR_HD PF07698.6 EKG21894.1 - 0.4 10.0 9.9 3.5 7.0 6.1 2.4 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase DUF2244 PF10003.4 EKG21894.1 - 2.5 7.4 5.5 2.5 7.4 0.8 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Zn_clus PF00172.13 EKG21895.1 - 3.1e-08 33.3 9.5 6.7e-08 32.3 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myticin-prepro PF10690.4 EKG21896.1 - 0.013 15.4 3.8 0.014 15.3 2.7 1.1 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Nucleoplasmin PF03066.10 EKG21897.1 - 0.00089 18.7 8.3 0.00089 18.7 5.8 1.7 2 0 0 2 2 2 1 Nucleoplasmin Sigma70_ner PF04546.8 EKG21897.1 - 0.0089 15.6 11.9 0.011 15.3 8.2 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF2457 PF10446.4 EKG21897.1 - 0.011 14.5 27.2 0.014 14.1 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EKG21897.1 - 0.023 12.6 14.3 0.025 12.5 9.9 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EKG21897.1 - 0.024 13.1 11.3 0.026 13.0 7.9 1.1 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 EKG21897.1 - 0.053 13.3 1.2 0.072 12.8 0.8 1.3 1 1 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EKG21897.1 - 0.14 10.2 10.7 0.15 10.1 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EKG21897.1 - 0.17 11.0 14.1 0.26 10.5 9.8 1.3 1 0 0 1 1 1 0 NOA36 protein HSP90 PF00183.13 EKG21897.1 - 0.2 9.9 9.2 0.24 9.7 6.4 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 EKG21897.1 - 0.21 10.9 12.8 0.3 10.4 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med17 PF10156.4 EKG21897.1 - 0.23 9.6 3.6 0.25 9.5 2.5 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF2722 PF10846.3 EKG21897.1 - 0.36 9.7 8.7 0.42 9.5 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Cwf_Cwc_15 PF04889.7 EKG21897.1 - 0.94 9.1 16.6 0.34 10.5 9.8 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.5 EKG21897.1 - 2.1 8.3 12.8 0.29 11.1 6.1 1.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Glyco_hydro_3 PF00933.16 EKG21899.1 - 8.4e-61 205.5 0.0 1.1e-59 201.8 0.0 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG21899.1 - 7.7e-31 107.3 3.4 4.4e-30 104.8 2.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Corona_S2 PF01601.11 EKG21899.1 - 0.1 10.6 0.0 0.15 10.0 0.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF605 PF04652.11 EKG21900.1 - 0.84 8.9 14.9 1.1 8.5 10.3 1.3 1 0 0 1 1 1 0 Vta1 like HET PF06985.6 EKG21901.1 - 2.8e-32 111.7 0.1 4.5e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40 PF00400.27 EKG21902.1 - 6.8e-44 146.2 22.2 3.6e-11 42.4 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EKG21902.1 - 2.4e-07 29.3 6.6 0.062 11.4 0.1 5.0 2 1 1 5 5 5 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 EKG21902.1 - 0.0057 15.5 1.2 3.1 6.6 0.0 3.3 1 1 4 5 5 5 2 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 EKG21902.1 - 0.018 13.8 0.0 10 4.7 0.0 3.1 1 1 2 3 3 3 0 Nup133 N terminal like Hira PF07569.6 EKG21902.1 - 0.029 13.6 0.2 11 5.1 0.0 2.8 2 1 1 3 3 3 0 TUP1-like enhancer of split RicinB_lectin_2 PF14200.1 EKG21902.1 - 0.053 13.8 0.1 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like DUF3312 PF11768.3 EKG21902.1 - 0.074 11.2 0.0 0.12 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Formyl_trans_N PF00551.14 EKG21904.1 - 5.6e-23 81.4 0.0 7.6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DUF765 PF05570.6 EKG21904.1 - 0.041 13.8 1.4 0.12 12.3 1.0 1.8 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) SAP PF02037.22 EKG21906.1 - 9.6e-07 28.1 0.1 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain Asp PF00026.18 EKG21907.1 - 4.1e-61 206.9 4.4 7.4e-61 206.1 3.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG21907.1 - 0.0011 19.4 1.7 2.9 8.4 0.2 3.2 2 1 0 2 2 2 2 Aspartyl protease Herpes_TAF50 PF03326.8 EKG21907.1 - 3.3 6.5 8.1 5.2 5.8 5.6 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) BPL_LplA_LipB PF03099.14 EKG21908.1 - 3.4e-15 56.1 0.0 9.7e-15 54.6 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ecl1 PF12855.2 EKG21910.1 - 1.8e-10 39.8 1.4 3.2e-10 39.1 0.9 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 EKG21910.1 - 0.066 12.7 0.2 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) WD40 PF00400.27 EKG21911.1 - 4.1e-30 102.5 6.1 3.4e-10 39.3 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EKG21911.1 - 2.3e-05 24.1 0.0 0.003 17.2 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EKG21911.1 - 5.2e-05 22.4 0.4 0.041 12.9 0.0 3.4 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EKG21911.1 - 0.0043 15.4 0.0 0.27 9.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EKG21911.1 - 0.017 13.2 0.1 0.074 11.1 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF3833 PF12915.2 EKG21911.1 - 0.039 13.1 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) Ribosomal_L32p PF01783.18 EKG21912.1 - 3.2e-12 46.4 4.7 4.5e-12 45.9 3.3 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Sgf11 PF08209.6 EKG21912.1 - 0.056 12.7 2.7 2 7.7 0.1 2.4 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DZR PF12773.2 EKG21912.1 - 0.081 12.7 1.7 0.16 11.8 1.2 1.5 1 1 0 1 1 1 0 Double zinc ribbon Rad50_zn_hook PF04423.9 EKG21912.1 - 0.21 11.1 0.1 0.21 11.1 0.1 1.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-ribbon_3 PF13248.1 EKG21912.1 - 0.36 10.0 4.9 0.63 9.3 3.4 1.4 1 1 0 1 1 1 0 zinc-ribbon domain zf-Mss51 PF13824.1 EKG21912.1 - 2.1 8.2 4.4 1.1 9.1 1.5 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Cys_rich_CPXG PF14255.1 EKG21912.1 - 4.5 7.1 5.4 1.8 8.4 0.4 2.1 1 1 1 2 2 2 0 Cysteine-rich CPXCG Septin PF00735.13 EKG21913.1 - 3.1e-111 370.8 0.1 4e-111 370.5 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EKG21913.1 - 1.5e-06 28.1 0.0 2.4e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EKG21913.1 - 3.5e-06 26.2 0.0 6.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EKG21913.1 - 1.8e-05 23.9 0.0 3.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EKG21913.1 - 9.9e-05 21.8 0.1 0.0047 16.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EKG21913.1 - 0.0013 18.6 0.4 1.4 8.6 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EKG21913.1 - 0.0033 16.9 0.2 0.0044 16.5 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 EKG21913.1 - 0.0086 16.3 0.2 0.017 15.4 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 EKG21913.1 - 0.011 16.0 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EKG21913.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EKG21913.1 - 0.017 14.0 0.0 0.057 12.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EKG21913.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG21913.1 - 0.021 14.8 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 EKG21913.1 - 0.029 13.5 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EKG21913.1 - 0.046 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EKG21913.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EKG21914.1 - 2.8e-29 101.8 0.0 3.4e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase Thymidylate_kin PF02223.12 EKG21914.1 - 0.011 15.1 0.2 0.017 14.5 0.2 1.5 1 1 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.1 EKG21914.1 - 0.046 13.5 0.1 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1895 PF08988.5 EKG21914.1 - 0.05 13.6 0.1 0.091 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) cwf21 PF08312.7 EKG21914.1 - 0.24 11.2 1.8 0.5 10.2 1.3 1.5 1 0 0 1 1 1 0 cwf21 domain WD40 PF00400.27 EKG21915.1 - 6.5e-17 60.6 15.5 0.00023 20.9 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat FliO PF04347.8 EKG21915.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO Rad52_Rad22 PF04098.10 EKG21916.1 - 2.7e-60 202.5 0.0 3.8e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Peptidase_S10 PF00450.17 EKG21917.1 - 1.1e-111 373.9 0.0 1.4e-111 373.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EKG21917.1 - 0.0027 17.6 0.0 0.011 15.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Endosulfine PF04667.12 EKG21918.1 - 1.3e-21 76.3 0.0 2.1e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EKG21919.1 - 5.9e-50 169.4 0.0 6.5e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase adh_short PF00106.20 EKG21920.1 - 1.2e-28 100.1 0.0 1.6e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG21920.1 - 4.6e-26 92.0 0.0 5.5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG21920.1 - 4.9e-13 49.1 0.0 6.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EKG21920.1 - 0.00015 21.0 0.0 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EKG21920.1 - 0.0014 18.3 0.2 0.003 17.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EMP24_GP25L PF01105.19 EKG21921.1 - 3.8e-21 75.6 0.0 5.8e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 EKG21921.1 - 0.023 15.1 0.3 0.1 13.0 0.2 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1319 PF07028.6 EKG21921.1 - 0.049 13.8 0.3 0.075 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Med5 PF08689.5 EKG21922.1 - 3.5e-229 763.1 0.0 4.2e-229 762.9 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF2683 PF10884.3 EKG21922.1 - 0.086 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2683) DUF2711 PF10924.3 EKG21922.1 - 0.18 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) Aldo_ket_red PF00248.16 EKG21924.1 - 2.7e-45 154.3 0.0 3.3e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ELFV_dehydrog PF00208.16 EKG21925.1 - 1.2e-85 286.9 4.8 1.5e-85 286.6 3.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EKG21925.1 - 4.6e-49 165.3 0.0 1.5e-48 163.7 0.0 1.8 2 1 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EKG21925.1 - 0.089 13.0 0.3 0.28 11.4 0.2 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding YopH_N PF09013.5 EKG21925.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 YopH, N-terminal CHD5 PF04420.9 EKG21926.1 - 2.9e-54 183.0 0.4 3.9e-54 182.6 0.3 1.2 1 0 0 1 1 1 1 CHD5-like protein GRAB PF10375.4 EKG21930.1 - 6.1e-09 35.1 0.1 1.3e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Rootletin PF15035.1 EKG21930.1 - 0.0023 17.9 60.1 0.19 11.6 9.1 3.8 2 1 1 4 4 4 3 Ciliary rootlet component, centrosome cohesion TSC22 PF01166.13 EKG21930.1 - 0.0025 17.7 4.3 0.0025 17.7 3.0 5.5 4 1 3 7 7 7 1 TSC-22/dip/bun family Reo_sigmaC PF04582.7 EKG21930.1 - 0.0027 16.9 10.5 0.085 12.0 0.7 3.0 2 1 1 3 3 3 2 Reovirus sigma C capsid protein Cast PF10174.4 EKG21930.1 - 0.011 13.8 58.0 0.047 11.7 40.1 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone bZIP_1 PF00170.16 EKG21930.1 - 0.017 15.0 4.1 0.017 15.0 2.8 5.1 4 0 0 4 4 4 0 bZIP transcription factor Lectin_N PF03954.9 EKG21930.1 - 0.017 14.4 1.7 0.017 14.4 1.2 3.2 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain Filament PF00038.16 EKG21930.1 - 0.025 14.0 51.7 0.077 12.4 25.8 2.6 1 1 1 2 2 2 0 Intermediate filament protein HALZ PF02183.13 EKG21930.1 - 0.027 14.1 2.7 0.027 14.1 1.9 4.4 4 1 0 4 4 3 0 Homeobox associated leucine zipper WEMBL PF05701.6 EKG21930.1 - 0.24 9.8 47.1 0.039 12.4 12.9 2.8 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 EKG21930.1 - 0.6 9.9 21.9 3.2 7.5 1.4 4.1 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 EKG21930.1 - 0.65 8.8 50.5 0.41 9.5 11.7 3.3 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 EKG21930.1 - 0.66 9.0 58.4 0.016 14.2 16.1 2.8 1 1 2 3 3 3 0 Tropomyosin Prefoldin PF02996.12 EKG21930.1 - 0.85 9.2 33.2 0.32 10.6 2.4 5.4 2 2 3 5 5 5 0 Prefoldin subunit DUF3584 PF12128.3 EKG21930.1 - 0.95 6.7 52.6 2.2 5.4 36.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 EKG21930.1 - 1.1 9.0 55.9 0.66 9.8 12.9 4.3 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 EKG21930.1 - 1.4 7.2 38.5 0.028 12.8 6.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Phage_GP20 PF06810.6 EKG21930.1 - 1.7 8.0 44.2 1.2 8.5 4.6 3.6 2 2 1 3 3 3 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 EKG21930.1 - 2.5 8.4 22.1 3.7 7.8 0.7 4.6 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.5 EKG21930.1 - 2.6 8.3 35.9 0.064 13.4 2.0 5.0 2 1 2 5 5 5 0 Tup N-terminal DUF883 PF05957.8 EKG21930.1 - 3.1 8.2 41.3 3.3 8.1 3.9 5.3 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) TPR_MLP1_2 PF07926.7 EKG21930.1 - 3.7 7.3 61.6 0.28 10.9 6.7 4.6 2 1 4 6 6 5 0 TPR/MLP1/MLP2-like protein Tweety PF04906.8 EKG21930.1 - 4.3 5.6 14.0 2.1 6.7 1.5 2.6 1 1 0 2 2 2 0 Tweety DUF972 PF06156.8 EKG21930.1 - 6 7.2 42.6 0.071 13.4 5.0 4.8 2 1 3 5 5 4 0 Protein of unknown function (DUF972) DUF4618 PF15397.1 EKG21930.1 - 7.5 5.8 40.1 3.3 6.9 17.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) FlaC_arch PF05377.6 EKG21930.1 - 8.1 6.4 18.8 28 4.6 0.3 5.5 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) HMA PF00403.21 EKG21932.1 - 3.5e-09 36.6 2.9 0.00028 20.9 0.1 2.1 2 0 0 2 2 2 2 Heavy-metal-associated domain BRO1 PF03097.13 EKG21933.1 - 1e-118 396.3 1.4 1.3e-118 396.0 0.0 1.8 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EKG21933.1 - 3.4e-86 288.8 14.1 3.4e-86 288.8 9.7 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV zf-H2C2_2 PF13465.1 EKG21934.1 - 1.7e-15 56.4 6.3 2.2e-08 33.9 0.1 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EKG21934.1 - 8.9e-13 47.7 11.4 5.1e-06 26.5 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG21934.1 - 7.5e-12 44.6 11.2 1.9e-05 24.6 1.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG21934.1 - 4.8e-07 29.7 2.0 0.045 13.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EKG21934.1 - 7.4e-06 25.9 1.6 0.006 16.7 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EKG21934.1 - 0.018 15.1 1.5 0.034 14.2 1.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EKG21934.1 - 0.03 14.2 7.8 2.8 7.9 0.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 EKG21934.1 - 0.036 14.3 0.5 0.036 14.3 0.4 1.7 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L44 PF00935.14 EKG21934.1 - 0.094 12.7 2.2 2.4 8.2 0.1 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 LIM PF00412.17 EKG21934.1 - 0.21 11.7 2.9 2.3 8.3 2.0 2.2 1 1 1 2 2 2 0 LIM domain zf-BED PF02892.10 EKG21934.1 - 2 8.2 4.3 74 3.2 2.9 2.5 1 1 0 1 1 1 0 BED zinc finger Aldo_ket_red PF00248.16 EKG21935.1 - 4.7e-42 143.7 0.0 1.5e-20 73.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family EHN PF06441.7 EKG21936.1 - 2.3e-09 37.1 0.2 3.3e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Metallophos PF00149.23 EKG21937.1 - 0.028 13.8 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DUF2360 PF10152.4 EKG21938.1 - 9.4 6.5 10.1 40 4.4 7.0 1.8 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Gon7 PF08738.5 EKG21939.1 - 4.3e-11 42.7 0.7 1.9e-09 37.4 0.5 2.0 1 1 0 1 1 1 1 Gon7 family HbrB PF08539.6 EKG21940.1 - 1.6e-49 167.7 0.0 2.3e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 HbrB-like SPX PF03105.14 EKG21941.1 - 2.7e-14 53.6 9.9 2.7e-12 47.0 1.3 3.9 2 1 0 2 2 2 1 SPX domain VTC PF09359.5 EKG21941.1 - 4.7e-10 38.9 0.0 9.5e-07 28.1 0.0 2.9 3 0 0 3 3 3 2 VTC domain DUF3792 PF12670.2 EKG21941.1 - 0.0046 16.7 6.2 0.007 16.2 4.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) DUF2723 PF11028.3 EKG21941.1 - 0.21 11.0 2.3 0.38 10.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Mpp10 PF04006.7 EKG21942.1 - 2.6e-88 296.9 73.3 4.4e-87 292.8 50.8 2.0 1 1 0 1 1 1 1 Mpp10 protein DUF4635 PF15466.1 EKG21942.1 - 0.092 12.0 1.4 0.4 9.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) MFS_1 PF07690.11 EKG21943.1 - 1.2e-25 89.9 21.3 1e-22 80.3 14.7 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21943.1 - 2.6e-10 39.5 20.9 5.6e-08 31.8 6.4 4.4 3 2 1 4 4 4 2 Sugar (and other) transporter DUF1752 PF08550.5 EKG21944.1 - 7.9e-09 34.9 2.2 1.3e-08 34.2 1.5 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) AreA_N PF07573.6 EKG21944.1 - 0.019 15.5 0.2 0.033 14.7 0.1 1.4 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus ORC6 PF05460.8 EKG21946.1 - 0.081 12.0 0.3 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF3188 PF11384.3 EKG21946.1 - 3 7.4 5.6 0.87 9.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Vps39_1 PF10366.4 EKG21947.1 - 1.5e-33 115.0 0.3 3.3e-32 110.7 0.0 3.1 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EKG21947.1 - 4.8e-24 85.2 0.0 9.6e-24 84.2 0.0 1.5 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EKG21947.1 - 2.5e-13 50.1 0.0 9.2e-13 48.3 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EKG21947.1 - 1.7e-05 24.4 5.0 4.7e-05 23.0 0.8 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.23 EKG21947.1 - 0.00014 21.3 5.9 2.3 7.9 0.6 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EKG21947.1 - 0.00052 20.1 2.9 0.014 15.5 0.1 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EKG21947.1 - 0.00091 19.1 7.4 0.83 9.6 0.3 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EKG21947.1 - 0.0079 16.0 6.0 1.6 8.8 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EKG21947.1 - 0.011 16.4 3.0 8.5 7.1 0.1 4.0 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EKG21947.1 - 0.024 14.2 4.7 38 4.0 0.0 4.4 4 1 0 4 4 4 0 TPR repeat TPR_10 PF13374.1 EKG21947.1 - 0.029 14.3 0.5 23 5.1 0.1 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EKG21947.1 - 0.036 14.4 4.3 2.8 8.3 0.3 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EKG21947.1 - 0.036 14.6 2.1 48 4.9 0.1 4.8 3 2 2 5 5 4 0 Tetratricopeptide repeat DUF3164 PF11363.3 EKG21947.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3164) CPSF_A PF03178.10 EKG21947.1 - 0.23 10.5 0.0 2.8 6.9 0.0 2.1 2 0 0 2 2 2 0 CPSF A subunit region SPX PF03105.14 EKG21948.1 - 8.5e-51 173.3 5.2 1.1e-50 172.9 3.6 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EKG21948.1 - 2.5e-30 105.7 44.7 3.5e-30 105.3 31.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EKG21948.1 - 4.4e-16 58.4 45.7 8.4e-14 50.8 17.5 2.3 1 1 1 2 2 2 2 Citrate transporter Baculo_11_kDa PF06143.6 EKG21949.1 - 0.89 8.9 4.9 13 5.2 0.0 3.3 4 0 0 4 4 4 0 Baculovirus 11 kDa family Baculo_PEP_C PF04513.7 EKG21949.1 - 1 9.1 8.6 11 5.8 0.4 4.0 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus KH_1 PF00013.24 EKG21954.1 - 4.7e-29 99.8 10.3 2.7e-15 55.7 2.3 2.2 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EKG21954.1 - 1.9e-20 72.0 8.4 7e-11 41.5 1.1 2.6 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 EKG21954.1 - 1.3e-08 34.2 4.3 0.00076 18.9 0.5 2.3 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 EKG21954.1 - 6.6e-07 28.8 1.1 0.008 15.8 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.1 EKG21954.1 - 0.002 17.9 2.5 0.17 11.7 0.2 2.4 2 0 0 2 2 2 2 NusA-like KH domain SLS PF14611.1 EKG21954.1 - 0.17 11.2 0.0 8 5.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator DUF802 PF05650.6 EKG21954.1 - 0.22 11.6 0.2 0.22 11.6 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF802) Ald_Xan_dh_C2 PF02738.13 EKG21955.1 - 2.7e-200 666.3 1.3 3.8e-200 665.8 0.9 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EKG21955.1 - 9.3e-47 158.6 0.0 2e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EKG21955.1 - 2.8e-33 113.9 0.1 1.2e-32 111.8 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EKG21955.1 - 2.1e-32 111.4 0.0 5.3e-32 110.2 0.0 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EKG21955.1 - 1.3e-29 101.8 0.0 2.9e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EKG21955.1 - 5.4e-09 35.6 1.8 7.6e-09 35.2 0.1 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain C_GCAxxG_C_C PF09719.5 EKG21956.1 - 0.041 13.6 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Fungal_trans_2 PF11951.3 EKG21957.1 - 9.7e-22 77.0 0.1 1.2e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 EKG21958.1 - 2e-70 237.6 0.0 2.5e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG21959.1 - 2.9e-72 243.6 0.0 3.9e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 EKG21960.1 - 9.3e-92 307.7 0.0 1.1e-91 307.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MMR_HSR1 PF01926.18 EKG21961.1 - 0.00051 19.9 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1674 PF07896.7 EKG21963.1 - 8.1e-18 64.3 2.7 1.5e-17 63.5 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) DIOX_N PF14226.1 EKG21965.1 - 9.3e-27 93.8 0.0 1.5e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG21965.1 - 4.4e-22 78.2 0.0 7.9e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DnaI_N PF07319.6 EKG21965.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus TPR_11 PF13414.1 EKG21966.1 - 5.5e-26 90.0 11.9 1.8e-11 43.5 0.4 4.7 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EKG21966.1 - 7.1e-25 85.5 7.4 2.8e-08 33.0 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EKG21966.1 - 2e-23 80.3 9.9 4e-07 29.4 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EKG21966.1 - 1.5e-17 62.5 15.6 5.5e-06 26.5 0.3 7.0 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EKG21966.1 - 6.5e-17 60.2 2.3 0.001 19.0 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EKG21966.1 - 2.4e-15 56.7 16.6 9.3e-07 29.3 0.3 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EKG21966.1 - 3.3e-14 51.4 3.4 0.0002 20.8 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EKG21966.1 - 7.4e-13 48.6 15.2 0.00045 20.4 0.0 5.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EKG21966.1 - 4.8e-12 45.6 14.1 5.3e-08 32.6 0.3 4.6 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EKG21966.1 - 6.2e-11 41.2 0.5 0.0044 16.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 EKG21966.1 - 1.8e-09 37.3 7.6 4e-05 23.3 0.1 4.0 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EKG21966.1 - 2.9e-08 33.6 11.8 0.0012 18.9 0.0 4.9 4 2 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EKG21966.1 - 5.6e-07 29.6 1.1 9e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EKG21966.1 - 3.2e-06 27.2 6.1 2.1 8.9 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 EKG21966.1 - 0.00025 20.7 0.0 0.78 9.5 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EKG21966.1 - 0.00026 20.1 1.7 0.47 9.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EKG21966.1 - 0.0011 18.8 7.9 0.2 11.6 0.7 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1641 PF07849.6 EKG21966.1 - 0.099 12.2 0.2 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) MFS_1 PF07690.11 EKG21968.1 - 6.4e-18 64.5 21.2 6.4e-18 64.5 14.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG21968.1 - 2.7e-05 22.9 3.0 2.7e-05 22.9 2.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter DUF3169 PF11368.3 EKG21968.1 - 0.09 11.9 0.0 0.09 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) QCR10 PF09796.4 EKG21968.1 - 0.17 11.5 0.6 1 9.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SH3_1 PF00018.23 EKG21970.1 - 1.2e-36 123.8 8.5 2.6e-12 45.9 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EKG21970.1 - 1.9e-36 123.5 0.0 3.9e-36 122.5 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EKG21970.1 - 2.7e-33 113.2 7.2 4.7e-11 42.0 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EKG21970.1 - 1.1e-24 85.6 0.2 1e-07 31.3 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.6 EKG21970.1 - 5.5e-11 42.3 190.3 6.2e-05 22.9 34.0 7.9 2 1 5 7 7 7 4 Domain of unknown function (DUF1720) SH3_3 PF08239.6 EKG21970.1 - 0.00042 20.4 2.0 0.033 14.3 0.1 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain HET PF06985.6 EKG21971.1 - 1.5e-19 70.5 0.0 3.7e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GXWXG PF14231.1 EKG21972.1 - 1.5e-17 62.9 0.5 3.2e-17 61.9 0.3 1.6 1 0 0 1 1 1 1 GXWXG protein DUF4334 PF14232.1 EKG21972.1 - 6.1e-17 61.0 0.1 1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4334) Pirin PF02678.11 EKG21973.1 - 8.5e-32 109.2 0.0 1.6e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EKG21973.1 - 7.3e-24 83.8 0.0 2.1e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EKG21973.1 - 4.9e-07 29.1 0.2 1.1e-05 24.8 0.4 2.4 2 0 0 2 2 2 1 Cupin domain Atg14 PF10186.4 EKG21974.1 - 3.5e-27 95.1 0.0 4.5e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Glyco_hydro_17 PF00332.13 EKG21975.1 - 1.7e-05 23.9 0.2 0.00082 18.4 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 CPSase_L_D2 PF02786.12 EKG21976.1 - 3.4e-23 82.0 0.0 5.2e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 EKG21976.1 - 1.1e-22 80.6 0.2 5.3e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG21976.1 - 4e-12 45.5 0.0 1.9e-11 43.3 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EKG21976.1 - 2.1e-10 40.2 0.0 4.7e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_chain PF00289.17 EKG21976.1 - 4.1e-10 39.7 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Dala_Dala_lig_C PF07478.8 EKG21976.1 - 6.8e-09 35.4 0.1 1.3e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EKG21976.1 - 1e-08 34.8 0.1 2.7e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EKG21976.1 - 0.0035 16.9 0.1 0.0069 15.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.16 EKG21976.1 - 0.044 13.2 0.3 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family IR1-M PF12185.3 EKG21976.1 - 0.044 13.4 0.3 0.096 12.4 0.2 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain CPSase_L_D2 PF02786.12 EKG21977.1 - 1.4e-81 272.7 0.0 2.3e-81 272.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EKG21977.1 - 2e-41 140.5 0.0 4.5e-41 139.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EKG21977.1 - 8e-18 64.5 0.1 2.5e-14 53.3 0.0 3.2 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EKG21977.1 - 2.7e-13 50.0 0.0 6.6e-13 48.8 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EKG21977.1 - 2.4e-09 36.3 0.0 0.00028 19.7 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EKG21977.1 - 5.7e-07 29.0 0.0 1.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain zf-C2H2_jaz PF12171.3 EKG21977.1 - 3.1e-05 23.9 10.3 0.0076 16.3 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Dala_Dala_lig_C PF07478.8 EKG21977.1 - 0.00013 21.4 0.0 0.00029 20.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.1 EKG21977.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain zf-met PF12874.2 EKG21977.1 - 0.57 10.4 14.1 2.2 8.6 2.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EKG21977.1 - 1.8 8.7 7.5 7.2 6.7 1.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EKG21977.1 - 2.2 8.7 10.0 2 8.8 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain SNase PF00565.12 EKG21978.1 - 1.4e-25 89.6 0.2 1.4e-25 89.6 0.1 1.9 2 0 0 2 2 2 1 Staphylococcal nuclease homologue Nol1_Nop2_Fmu PF01189.12 EKG21979.1 - 1.3e-15 57.5 0.0 4e-14 52.6 0.0 2.5 1 1 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EKG21979.1 - 0.00031 20.7 0.6 0.00052 20.0 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EKG21979.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase HET PF06985.6 EKG21981.1 - 5.2e-34 117.3 0.1 9.1e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) URO-D PF01208.12 EKG21982.1 - 1.1e-122 409.2 0.0 1.3e-122 409.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 EKG21982.1 - 0.079 12.5 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 Phloem filament protein PP1 MutS_III PF05192.13 EKG21983.1 - 2.9e-31 108.8 5.0 5.5e-31 107.9 3.5 1.4 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EKG21983.1 - 8.7e-09 35.5 0.0 3.8e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EKG21983.1 - 2e-05 24.6 0.0 0.05 13.6 0.0 2.4 2 0 0 2 2 2 2 MutS domain I DUF3405 PF11885.3 EKG21983.1 - 0.089 11.0 0.0 0.13 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) MutS_III PF05192.13 EKG21984.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EKG21984.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 MutS family domain IV Hexapep_2 PF14602.1 EKG21986.1 - 1.5e-15 56.4 8.5 5.1e-11 41.9 2.9 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EKG21986.1 - 1.2e-14 53.0 7.9 4.7e-11 41.6 3.1 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EKG21986.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase RRM_1 PF00076.17 EKG21988.1 - 1.1e-36 124.2 0.1 1.1e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG21988.1 - 1.7e-26 91.9 0.2 1.1e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG21988.1 - 4.3e-17 61.7 0.0 3.7e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EKG21988.1 - 1.7e-05 24.4 0.4 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 Limkain b1 Senescence PF06911.7 EKG21988.1 - 0.011 15.4 4.7 0.011 15.4 3.3 1.6 2 0 0 2 2 2 0 Senescence-associated protein Nup35_RRM PF05172.8 EKG21988.1 - 0.069 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Pyr_redox_2 PF07992.9 EKG21989.1 - 5.3e-30 104.8 0.0 1e-29 103.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG21989.1 - 4.4e-16 59.0 1.3 7.3e-14 51.9 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EKG21989.1 - 4.6e-12 46.4 0.1 1.5e-06 28.3 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG21989.1 - 1.1e-06 27.8 1.8 0.00012 21.3 0.1 2.7 2 1 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EKG21989.1 - 2.1e-06 27.1 0.5 1.5e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EKG21989.1 - 2.4e-06 26.6 1.7 0.00064 18.6 0.1 3.6 4 0 0 4 4 4 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EKG21989.1 - 1.6e-05 23.9 1.4 0.028 13.3 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EKG21989.1 - 3e-05 23.0 4.9 0.018 13.9 0.3 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EKG21989.1 - 0.00019 20.0 0.4 0.005 15.3 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.1 EKG21989.1 - 0.0013 18.9 0.4 0.18 12.0 0.0 2.9 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EKG21989.1 - 0.0023 17.9 0.1 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG21989.1 - 0.0088 14.9 1.5 0.0088 14.9 1.0 2.9 2 1 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.15 EKG21989.1 - 0.036 14.1 0.9 1.4 9.0 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EKG21989.1 - 0.079 11.1 0.0 0.16 10.1 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 EKG21989.1 - 0.084 11.4 0.2 0.57 8.7 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase WD40 PF00400.27 EKG21990.1 - 9.8e-06 25.2 0.4 0.014 15.2 0.0 3.7 3 1 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 EKG21990.1 - 0.019 14.0 0.0 0.04 13.0 0.0 1.5 2 0 0 2 2 2 0 CPSF A subunit region Ribosomal_L10 PF00466.15 EKG21991.1 - 2.5e-26 91.5 0.1 4.8e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EKG21991.1 - 7.4e-21 74.3 5.7 1.4e-20 73.4 2.2 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DnaJ PF00226.26 EKG21992.1 - 1.7e-25 88.5 3.0 3.1e-25 87.6 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EKG21992.1 - 1.9e-22 78.9 0.3 1.8e-19 69.4 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EKG21992.1 - 1.2e-14 54.0 17.1 2.3e-14 53.1 11.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EKG21992.1 - 0.023 14.3 8.9 0.1 12.3 1.5 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EKG21992.1 - 0.16 11.7 5.9 2.3 8.0 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 EKG21992.1 - 0.35 10.6 6.1 3.2 7.5 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zf-RING_3 PF14369.1 EKG21992.1 - 4.3 7.4 6.9 14 5.7 0.0 3.4 4 0 0 4 4 4 0 zinc-finger Zn_Tnp_IS1595 PF12760.2 EKG21992.1 - 8.7 6.2 9.1 15 5.5 1.4 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain dCMP_cyt_deam_1 PF00383.17 EKG21993.1 - 2.7e-24 84.7 0.0 3.6e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EKG21993.1 - 0.0017 18.1 0.4 0.085 12.7 0.3 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 EKG21993.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.4 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase Atg14 PF10186.4 EKG21995.1 - 4.2e-31 108.0 12.1 5e-31 107.7 8.4 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF3138 PF11336.3 EKG21995.1 - 0.011 13.9 0.8 0.013 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.6 EKG21995.1 - 0.019 13.6 2.8 0.023 13.3 2.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CR6_interact PF10147.4 EKG21995.1 - 0.081 12.2 7.4 0.11 11.7 5.2 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Syntaxin PF00804.20 EKG21995.1 - 0.21 11.7 4.4 0.39 10.9 3.0 1.4 1 0 0 1 1 1 0 Syntaxin APG6 PF04111.7 EKG21995.1 - 0.29 10.1 4.1 0.35 9.8 2.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 EKG21995.1 - 1.3 8.8 5.1 3.5 7.5 3.3 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ZZ PF00569.12 EKG21995.1 - 1.7 8.2 5.1 0.87 9.1 1.3 2.0 2 0 0 2 2 2 0 Zinc finger, ZZ type FAD_binding_4 PF01565.18 EKG21996.1 - 5.9e-18 64.6 0.8 1.2e-17 63.7 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EKG21996.1 - 5.2e-10 39.0 0.1 9.9e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EKG21996.1 - 0.029 13.5 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF3659 PF12396.3 EKG21997.1 - 0 994.1 189.5 2.4e-25 87.9 1.8 15.9 17 0 0 17 17 17 14 Protein of unknown function (DUF3659) IQ PF00612.22 EKG21998.1 - 0.00028 20.2 0.5 0.0011 18.4 0.4 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Abhydrolase_3 PF07859.8 EKG21999.1 - 2e-55 187.6 1.3 2e-55 187.6 0.2 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG21999.1 - 7e-08 32.3 0.0 1.5e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG21999.1 - 0.00011 21.4 0.1 0.00022 20.5 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EKG21999.1 - 0.00027 20.4 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EKG21999.1 - 0.0038 15.7 0.0 0.059 11.8 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 EKG21999.1 - 0.011 14.3 0.0 0.019 13.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) COesterase PF00135.23 EKG21999.1 - 0.063 11.9 0.3 0.41 9.3 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family zf-HC5HC2H_2 PF13832.1 EKG22000.1 - 3.6e-19 68.7 2.6 3.6e-19 68.7 1.8 4.0 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EKG22000.1 - 2e-16 59.8 3.9 2e-16 59.8 2.7 4.7 5 0 0 5 5 5 2 PHD-like zinc-binding domain PHD PF00628.24 EKG22000.1 - 4.9e-14 51.7 53.6 1e-06 28.2 4.6 6.3 6 0 0 6 6 6 3 PHD-finger BAH PF01426.13 EKG22000.1 - 4e-12 45.9 0.0 1.2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.1 EKG22000.1 - 4.3e-09 35.5 5.7 4.3e-09 35.5 4.0 5.6 7 0 0 7 7 7 2 PHD-finger C1_1 PF00130.17 EKG22000.1 - 1.2 8.8 52.2 0.01 15.5 3.6 5.5 6 1 1 7 7 7 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3752 PF12572.3 EKG22001.1 - 2.6e-37 128.2 2.0 2.9e-37 128.1 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Herpes_UL56 PF04534.7 EKG22001.1 - 0.05 13.3 0.5 0.069 12.8 0.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Nop14 PF04147.7 EKG22003.1 - 1.6e-233 777.3 30.6 8e-183 609.6 13.3 2.0 1 1 1 2 2 2 2 Nop14-like family WLM PF08325.5 EKG22004.1 - 1.5e-50 171.6 0.0 2.8e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EKG22004.1 - 0.0066 15.5 18.0 0.06 12.4 2.6 3.4 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EKG22004.1 - 0.18 11.6 10.6 1.5 8.6 7.7 2.1 1 1 1 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EKG22004.1 - 2 8.1 13.5 0.28 10.9 1.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1776 PF08643.5 EKG22005.1 - 4.5e-92 308.3 0.0 5.6e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) TrbC PF04956.8 EKG22005.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 TrbC/VIRB2 family Sel1 PF08238.7 EKG22006.1 - 3.3e-12 46.6 11.2 0.0021 18.6 0.1 4.4 4 0 0 4 4 4 3 Sel1 repeat zf-MYND PF01753.13 EKG22007.1 - 1.4e-11 44.0 19.5 2.4e-11 43.2 13.5 1.4 1 0 0 1 1 1 1 MYND finger zf-ribbon_3 PF13248.1 EKG22007.1 - 0.013 14.6 2.8 0.027 13.6 1.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HpcH_HpaI PF03328.9 EKG22008.1 - 1.5e-41 141.7 0.0 2.6e-41 140.9 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EKG22008.1 - 1.9e-14 53.2 0.0 1.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold DUF846 PF05832.7 EKG22009.1 - 8.1e-52 174.7 10.0 9.6e-52 174.4 6.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Use1 PF09753.4 EKG22011.1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 zf-B_box PF00643.19 EKG22012.1 - 0.0086 15.9 1.5 0.012 15.4 1.1 1.2 1 0 0 1 1 1 1 B-box zinc finger MFS_1 PF07690.11 EKG22014.1 - 4.4e-42 144.0 52.3 1.8e-40 138.7 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cgr1 PF03879.9 EKG22015.1 - 4.7e-38 129.7 27.6 5.6e-38 129.4 19.1 1.0 1 0 0 1 1 1 1 Cgr1 family DRY_EERY PF09750.4 EKG22015.1 - 0.65 10.1 6.4 0.9 9.6 4.5 1.3 1 0 0 1 1 1 0 Alternative splicing regulator PRP1_N PF06424.7 EKG22015.1 - 0.69 10.2 9.5 0.79 10.0 6.6 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GAGA_bind PF06217.7 EKG22015.1 - 3.7 7.4 12.0 4.1 7.2 8.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EKG22015.1 - 7.4 6.3 14.0 9.1 6.0 9.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hom_end_hint PF05203.11 EKG22015.1 - 9.1 5.9 7.1 11 5.6 4.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Mito_carr PF00153.22 EKG22016.1 - 2.2e-65 216.4 1.0 1.6e-23 82.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YpzI PF14140.1 EKG22019.1 - 0.059 12.8 0.2 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 YpzI-like protein PWI PF01480.12 EKG22020.1 - 2e-26 91.8 0.1 3.1e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 PWI domain Lactamase_B PF00753.22 EKG22021.1 - 7.1e-05 22.5 0.0 0.00016 21.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Fasciclin PF02469.17 EKG22022.1 - 5.3e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain DUF3807 PF12720.2 EKG22023.1 - 3.3e-14 53.4 7.1 3.3e-14 53.4 4.9 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3807) Yae1_N PF09811.4 EKG22023.1 - 0.00095 18.6 3.9 0.0017 17.8 2.7 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal PAPA-1 PF04795.7 EKG22023.1 - 8.9 7.0 14.0 3.4 8.4 5.8 2.4 2 1 0 2 2 2 0 PAPA-1-like conserved region Metallophos PF00149.23 EKG22024.1 - 1.9e-10 40.5 1.6 0.00015 21.2 0.1 2.7 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Amino_oxidase PF01593.19 EKG22025.1 - 1.3e-39 136.6 0.4 1.7e-26 93.3 0.3 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EKG22025.1 - 8.9e-09 35.2 0.0 2.9e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EKG22025.1 - 0.0011 18.0 0.4 0.0021 17.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EKG22025.1 - 0.016 15.2 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG22025.1 - 0.1 13.0 0.2 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PPR_3 PF13812.1 EKG22026.1 - 2.2e-06 27.5 3.9 0.89 9.9 0.0 6.7 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EKG22026.1 - 5.1e-06 26.3 0.0 0.052 13.5 0.0 3.8 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 EKG22026.1 - 0.1 12.5 0.0 36 4.6 0.0 4.4 5 0 0 5 5 5 0 PPR repeat SCRL PF06876.7 EKG22027.1 - 1.2 9.1 5.1 0.13 12.1 0.3 1.8 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Pkinase PF00069.20 EKG22028.1 - 3.4e-56 190.2 0.0 5.4e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG22028.1 - 3.6e-36 124.5 0.0 5.3e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EKG22028.1 - 0.00024 20.1 0.0 0.0014 17.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EKG22028.1 - 0.002 17.2 0.1 0.03 13.4 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EKG22028.1 - 0.0046 16.7 0.0 0.038 13.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RRN3 PF05327.6 EKG22030.1 - 6.5e-173 575.8 0.2 8.4e-173 575.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3993 PF13158.1 EKG22030.1 - 0.061 13.1 0.1 0.41 10.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3993) Sporozoite_P67 PF05642.6 EKG22030.1 - 0.62 7.8 2.5 1 7.1 1.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aldolase_II PF00596.16 EKG22032.1 - 1e-25 90.4 0.0 1.2e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NmrA PF05368.8 EKG22033.1 - 5.8e-17 61.7 0.0 8.5e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EKG22033.1 - 3.1e-08 33.8 0.0 5.1e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG22033.1 - 0.016 14.9 0.0 0.077 12.6 0.0 2.0 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.14 EKG22033.1 - 0.024 13.3 0.0 0.055 12.1 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EKG22033.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EKG22033.1 - 0.068 13.4 0.0 0.2 11.9 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EKG22033.1 - 0.07 13.0 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase PWWP PF00855.12 EKG22034.1 - 3.4e-13 49.6 0.3 3.4e-13 49.6 0.2 2.8 2 1 0 2 2 2 1 PWWP domain ThiF PF00899.16 EKG22035.1 - 1.6e-37 128.3 0.1 3.1e-37 127.4 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EKG22035.1 - 1.1e-24 85.7 1.1 2.2e-24 84.8 0.7 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EKG22035.1 - 2.6e-24 84.7 0.1 6e-24 83.6 0.1 1.6 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EKG22035.1 - 1.1e-14 53.5 2.4 2.1e-14 52.6 1.7 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EKG22035.1 - 0.00045 20.3 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase CBS PF00571.23 EKG22035.1 - 0.0027 17.4 0.0 2.7 7.8 0.0 3.3 2 1 0 2 2 2 2 CBS domain DAO PF01266.19 EKG22035.1 - 0.19 10.6 0.0 0.33 9.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Telomere_reg-2 PF10193.4 EKG22036.1 - 2.2e-38 131.0 0.0 8.7e-38 129.0 0.0 2.1 1 0 0 1 1 1 1 Telomere length regulation protein SF3b1 PF08920.5 EKG22037.1 - 1.6e-34 119.0 4.6 2.7e-34 118.3 0.0 2.9 1 1 2 3 3 3 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EKG22037.1 - 1.9e-17 63.3 1.8 0.011 16.0 0.0 7.9 5 3 5 10 10 10 6 HEAT repeats HEAT_EZ PF13513.1 EKG22037.1 - 6.8e-13 48.6 0.6 0.17 12.3 0.0 9.1 8 1 1 9 9 9 2 HEAT-like repeat HEAT PF02985.17 EKG22037.1 - 7.7e-12 44.2 6.4 0.14 12.2 0.1 9.2 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 EKG22037.1 - 2.2e-06 26.2 0.1 0.018 13.3 0.0 3.5 3 1 0 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EKG22037.1 - 1.1e-05 25.7 0.7 1.4 9.3 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EKG22037.1 - 0.0053 16.1 0.0 0.94 8.7 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal NUC173 PF08161.7 EKG22037.1 - 0.014 14.7 0.3 12 5.2 0.0 4.0 5 0 0 5 5 5 0 NUC173 domain DUF1388 PF07142.7 EKG22037.1 - 0.024 14.3 0.5 0.044 13.4 0.3 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) Abhydrolase_6 PF12697.2 EKG22039.1 - 6.5e-16 58.9 0.1 1.6e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG22039.1 - 3.9e-08 33.1 0.0 1.2e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG22039.1 - 0.0055 16.2 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EKG22039.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF726 PF05277.7 EKG22040.1 - 1.2e-128 428.9 3.3 1.5e-128 428.5 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.7 EKG22041.1 - 2.2e-30 104.6 0.8 4.1e-30 103.8 0.5 1.4 1 0 0 1 1 1 1 Fcf1 Abhydrolase_6 PF12697.2 EKG22042.1 - 1e-18 68.0 3.4 1.4e-18 67.6 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG22042.1 - 3e-09 36.7 0.7 5.2e-09 36.0 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG22042.1 - 1.9e-06 27.6 0.0 0.00015 21.4 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EKG22042.1 - 0.032 13.6 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3672 PF12421.3 EKG22042.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III protein Lipase_3 PF01764.20 EKG22042.1 - 0.083 12.5 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Lipase (class 3) zf-C2H2_4 PF13894.1 EKG22043.1 - 4.1e-08 32.9 8.1 0.0014 18.7 0.4 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EKG22043.1 - 0.28 11.3 5.8 3.3 7.9 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EKG22043.1 - 0.74 10.2 14.4 1.5 9.3 0.1 4.0 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 EKG22043.1 - 4 7.7 7.1 7.1 6.9 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DUF106 PF01956.11 EKG22044.1 - 8.5e-60 201.0 0.3 1.3e-59 200.5 0.2 1.3 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 EKG22045.1 - 3.9e-54 182.5 0.1 5.1e-54 182.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-C2H2 PF00096.21 EKG22047.1 - 0.002 18.3 21.8 0.46 10.9 0.2 5.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EKG22047.1 - 0.82 10.1 23.4 14 6.2 0.3 5.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EKG22048.1 - 0.033 14.5 0.1 0.033 14.5 0.1 7.7 8 0 0 8 8 8 0 C2H2-type zinc finger C1_4 PF07975.7 EKG22048.1 - 0.81 9.7 19.2 0.47 10.4 0.1 4.2 3 1 0 3 3 3 0 TFIIH C1-like domain DUF3133 PF11331.3 EKG22048.1 - 0.97 9.0 7.2 5.5 6.6 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) zf-C2H2 PF00096.21 EKG22048.1 - 6.4 7.3 45.4 0.028 14.7 2.9 6.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type Sds3 PF08598.6 EKG22049.1 - 7.4e-14 51.7 15.1 7.4e-14 51.7 10.5 3.5 3 2 0 3 3 3 1 Sds3-like RRM_1 PF00076.17 EKG22050.1 - 5.8e-08 32.2 0.1 0.0023 17.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG22050.1 - 2.4e-05 24.0 0.0 0.0044 16.8 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG22050.1 - 3.6e-05 23.6 0.0 0.23 11.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.5 EKG22050.1 - 0.014 14.4 20.5 0.026 13.6 14.2 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EKG22050.1 - 0.019 12.9 14.8 0.027 12.4 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Spore_coat_CotO PF14153.1 EKG22050.1 - 1.7 8.0 11.3 3.8 6.9 7.8 1.6 1 0 0 1 1 1 0 Spore coat protein CotO DUF572 PF04502.8 EKG22050.1 - 2.5 7.2 16.2 1 8.4 9.7 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) Limkain-b1 PF11608.3 EKG22050.1 - 2.7 7.8 6.6 0.98 9.2 0.0 2.9 2 1 0 2 2 2 0 Limkain b1 Glyco_hydro_38 PF01074.17 EKG22051.1 - 2e-92 309.3 0.4 2e-92 309.3 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EKG22051.1 - 2.5e-75 254.0 0.0 8.3e-75 252.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EKG22051.1 - 3.3e-26 91.2 0.0 7.3e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain PX PF00787.19 EKG22052.1 - 5.1e-20 71.3 0.6 1.6e-19 69.7 0.2 2.0 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 EKG22052.1 - 3.2e-17 62.5 5.5 1.6e-08 34.1 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EKG22052.1 - 1.3e-06 28.1 2.4 2.5e-06 27.1 1.6 1.4 1 1 0 1 1 1 1 BAR domain ADIP PF11559.3 EKG22052.1 - 0.21 11.4 4.9 9.8 6.0 0.7 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4404 PF14357.1 EKG22052.1 - 3.6 8.0 5.9 2.7 8.4 1.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) IncA PF04156.9 EKG22052.1 - 3.7 7.0 6.3 2.6 7.5 0.0 2.4 2 1 0 2 2 2 0 IncA protein ADK PF00406.17 EKG22053.1 - 5e-35 120.5 0.0 2.7e-19 69.5 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EKG22053.1 - 5.3e-15 54.7 0.0 1.5e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EKG22053.1 - 6.7e-06 26.4 0.0 4.6e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG22053.1 - 5.3e-05 24.0 0.0 9.7e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG22053.1 - 0.00025 20.9 0.0 0.0076 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKG22053.1 - 0.089 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EKG22053.1 - 0.15 10.7 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein LETM1 PF07766.8 EKG22054.1 - 4.6e-104 347.2 0.1 8.1e-104 346.3 0.1 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EKG22054.1 - 3.6e-07 29.5 0.0 0.00053 19.4 0.0 3.0 3 0 0 3 3 3 2 SAP domain DUF1034 PF06280.7 EKG22056.1 - 0.0051 17.2 6.9 0.014 15.8 4.8 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) DUF1295 PF06966.7 EKG22057.1 - 9.9e-56 188.6 0.2 1.3e-55 188.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EKG22057.1 - 1.1e-05 25.2 0.1 1.1e-05 25.2 0.1 3.0 1 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EKG22057.1 - 0.00011 22.2 1.0 0.00019 21.5 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EKG22057.1 - 0.01 15.9 3.8 0.014 15.5 0.1 2.9 2 1 1 3 3 3 1 Phospholipid methyltransferase Pal1 PF08316.6 EKG22059.1 - 7.7e-07 29.6 0.2 1.8e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein PALP PF00291.20 EKG22060.1 - 2.7e-50 171.3 0.0 4.3e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 EKG22061.1 - 1.1e-34 119.9 0.0 2.3e-34 118.9 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Dynamitin PF04912.9 EKG22062.1 - 1.2e-17 63.8 0.5 6.1e-16 58.2 0.0 2.0 2 0 0 2 2 2 1 Dynamitin PLU-1 PF08429.6 EKG22062.1 - 0.0024 16.8 0.0 0.0045 15.9 0.0 1.4 1 1 0 1 1 1 1 PLU-1-like protein Ead_Ea22 PF13935.1 EKG22062.1 - 0.0087 16.4 7.1 0.32 11.3 1.3 2.3 1 1 1 2 2 2 2 Ead/Ea22-like protein Sipho_Gp157 PF05565.6 EKG22062.1 - 0.011 15.2 1.1 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1664 PF07889.7 EKG22062.1 - 0.018 14.8 0.5 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3584 PF12128.3 EKG22062.1 - 0.035 11.4 8.2 0.12 9.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 EKG22062.1 - 0.053 13.2 6.7 2.3 7.9 0.1 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.6 EKG22062.1 - 0.053 13.9 5.5 3.7 8.0 0.8 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF885 PF05960.6 EKG22062.1 - 0.059 12.5 4.2 0.1 11.7 2.9 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) SPX PF03105.14 EKG22062.1 - 0.067 12.9 0.7 0.1 12.3 0.4 1.4 1 1 0 1 1 1 0 SPX domain DUF4407 PF14362.1 EKG22062.1 - 0.07 12.0 4.7 0.062 12.2 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 EKG22062.1 - 0.094 12.5 6.6 0.43 10.4 1.3 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF2360 PF10152.4 EKG22062.1 - 0.1 12.9 3.1 0.19 12.0 2.1 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) LCD1 PF09798.4 EKG22062.1 - 0.11 10.5 0.1 0.13 10.1 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein MIS13 PF08202.6 EKG22062.1 - 0.11 11.5 2.1 2.3 7.2 0.3 2.1 2 0 0 2 2 2 0 Mis12-Mtw1 protein family DUF2413 PF10310.4 EKG22062.1 - 0.12 11.2 5.7 0.19 10.5 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) TMF_DNA_bd PF12329.3 EKG22062.1 - 0.12 12.2 7.0 2.9 7.7 0.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 EKG22062.1 - 0.13 12.5 1.5 1.6 9.0 0.1 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 EKG22062.1 - 0.15 11.7 4.5 0.24 11.0 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Syntaxin PF00804.20 EKG22062.1 - 0.16 12.1 4.3 0.66 10.1 1.0 2.2 2 0 0 2 2 2 0 Syntaxin DUF4200 PF13863.1 EKG22062.1 - 0.16 11.9 3.0 0.36 10.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CDV3 PF15359.1 EKG22062.1 - 0.2 11.7 2.2 0.41 10.7 0.2 2.0 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Muted PF14942.1 EKG22062.1 - 0.2 11.5 2.0 0.76 9.6 0.6 2.0 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Sec20 PF03908.8 EKG22062.1 - 0.23 11.1 1.2 12 5.7 0.4 2.2 2 0 0 2 2 2 0 Sec20 COG2 PF06148.6 EKG22062.1 - 0.33 10.8 3.5 3.8 7.3 0.7 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.8 EKG22062.1 - 0.4 11.0 12.8 5.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HAUS-augmin3 PF14932.1 EKG22062.1 - 0.42 9.7 5.1 0.34 10.0 1.5 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Synaptobrevin PF00957.16 EKG22062.1 - 0.54 9.9 2.1 0.92 9.1 0.4 2.1 2 0 0 2 2 2 0 Synaptobrevin IncA PF04156.9 EKG22062.1 - 0.71 9.4 6.0 4.7 6.7 1.6 2.1 2 0 0 2 2 2 0 IncA protein zf-C4H2 PF10146.4 EKG22062.1 - 0.72 9.8 3.4 6.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein Latarcin PF10279.4 EKG22062.1 - 1.1 9.5 4.3 7.2 6.8 3.0 2.1 1 1 0 1 1 1 0 Latarcin precursor FliD_N PF02465.13 EKG22062.1 - 1.1 9.7 11.8 0.68 10.3 5.9 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1192 PF06698.6 EKG22062.1 - 1.6 8.5 14.4 0.098 12.4 2.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF3138 PF11336.3 EKG22062.1 - 1.6 6.7 6.2 2.2 6.3 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DivIC PF04977.10 EKG22062.1 - 2.7 7.5 6.6 11 5.6 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Herpes_UL25 PF01499.11 EKG22062.1 - 7.7 4.6 9.1 15 3.7 3.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family Amino_oxidase PF01593.19 EKG22063.1 - 9.8e-88 295.1 0.0 2.7e-87 293.7 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EKG22063.1 - 3.3e-09 36.7 0.0 7.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EKG22063.1 - 4e-08 33.1 0.0 1.4e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG22063.1 - 8e-05 21.7 0.6 0.087 11.7 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HMG_box PF00505.14 EKG22063.1 - 0.0014 18.8 1.3 0.0014 18.8 0.9 2.5 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EKG22063.1 - 0.0061 16.9 1.0 0.016 15.5 0.7 1.8 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_3 PF13738.1 EKG22063.1 - 0.0063 16.5 0.1 1.1 9.2 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG22063.1 - 0.022 14.5 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EKG22063.1 - 0.043 12.7 0.2 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein UCH PF00443.24 EKG22064.1 - 1.1e-53 182.0 0.6 2.2e-53 181.1 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EKG22064.1 - 4e-25 88.8 0.6 4e-25 88.8 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF3332 PF11810.3 EKG22064.1 - 1.8 8.2 5.1 5 6.7 3.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Yos1 PF08571.5 EKG22066.1 - 4.9e-31 106.6 0.4 5.3e-31 106.5 0.3 1.0 1 0 0 1 1 1 1 Yos1-like HATPase_c PF02518.21 EKG22067.1 - 4.6e-30 103.6 0.1 1.1e-29 102.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EKG22067.1 - 1.1e-22 80.1 0.2 2.7e-22 78.8 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EKG22067.1 - 3.9e-21 74.8 0.1 3.9e-21 74.8 0.1 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EKG22067.1 - 7.5e-17 61.6 0.1 7.3e-09 35.9 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 EKG22067.1 - 4.5e-10 39.4 3.0 8.9e-08 32.1 2.1 2.6 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EKG22067.1 - 4.2e-08 33.2 0.4 0.00056 19.9 0.0 4.4 4 1 0 4 4 4 2 PAS fold PAS PF00989.19 EKG22067.1 - 8.9e-06 25.4 0.0 0.015 15.0 0.0 4.0 3 1 0 3 3 3 2 PAS fold HATPase_c_3 PF13589.1 EKG22067.1 - 0.00031 20.4 0.3 0.00083 19.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NuA4 PF09340.5 EKG22071.1 - 1.1e-26 92.3 0.3 1.4e-26 91.9 0.2 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Nup153 PF08604.5 EKG22071.1 - 0.073 11.7 0.5 0.16 10.5 0.3 1.5 1 1 0 1 1 1 0 Nucleoporin Nup153-like TFIIS_M PF07500.9 EKG22072.1 - 2e-31 108.4 4.4 3.8e-31 107.5 3.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EKG22072.1 - 2.3e-18 65.5 6.1 3.8e-18 64.8 4.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EKG22072.1 - 2.2e-13 49.4 1.4 3.9e-13 48.6 1.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain OrfB_Zn_ribbon PF07282.6 EKG22072.1 - 3 7.5 5.6 8 6.2 3.9 1.7 1 1 0 1 1 1 0 Putative transposase DNA-binding domain WD40 PF00400.27 EKG22074.1 - 2.3e-72 236.4 26.3 6.7e-08 32.1 0.1 12.5 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 EKG22074.1 - 3.7e-21 75.0 0.0 1.3e-20 73.2 0.0 2.0 3 0 0 3 3 3 1 Dip2/Utp12 Family Nup160 PF11715.3 EKG22074.1 - 0.00028 19.1 9.4 0.11 10.5 0.0 5.3 3 2 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EKG22074.1 - 0.00029 19.6 3.7 0.55 8.9 0.0 4.7 3 2 1 5 5 5 2 Nup133 N terminal like Nbas_N PF15492.1 EKG22074.1 - 0.0015 17.7 0.5 6.1 5.8 0.0 4.7 4 1 2 6 6 6 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EKG22074.1 - 0.064 12.9 0.2 22 4.6 0.0 4.3 4 1 0 5 5 5 0 Eukaryotic translation initiation factor eIF2A P34-Arc PF04045.9 EKG22075.1 - 3.1e-102 340.9 1.4 3.9e-102 340.6 1.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EKG22075.1 - 0.0011 18.3 0.7 0.0022 17.3 0.5 1.4 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DNA_mis_repair PF01119.14 EKG22076.1 - 1.2e-08 34.4 0.0 2.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain GET2 PF08690.5 EKG22076.1 - 1.9 7.6 12.2 1.1 8.4 2.4 2.6 3 0 0 3 3 3 0 GET complex subunit GET2 PAH PF02671.16 EKG22077.1 - 3.7e-45 151.2 0.8 1.9e-17 62.5 0.4 3.6 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EKG22077.1 - 3.2e-39 132.7 0.1 1.1e-38 131.0 0.0 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor MA3 PF02847.12 EKG22077.1 - 0.17 11.5 1.2 2.3 7.9 0.1 3.2 4 0 0 4 4 4 0 MA3 domain Glyco_hydro_3_C PF01915.17 EKG22078.1 - 1.3e-72 244.0 0.0 1.2e-70 237.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG22078.1 - 1.4e-20 73.0 0.0 3.7e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EKG22078.1 - 6.8e-19 67.9 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Glyco_hydro_3 PF00933.16 EKG22078.1 - 1.9e-14 53.3 0.0 2.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CbiK PF06180.6 EKG22078.1 - 0.0022 17.1 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) GvpK PF05121.7 EKG22078.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein K Fungal_trans PF04082.13 EKG22081.1 - 6.1e-23 81.0 0.1 1.2e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG22081.1 - 7.6e-05 22.5 6.2 0.00013 21.7 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COPIIcoated_ERV PF07970.7 EKG22082.1 - 3.8e-69 232.6 0.0 4.1e-45 154.1 0.0 2.4 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EKG22082.1 - 1.8e-33 114.3 0.2 4.2e-33 113.1 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sulfate_transp PF00916.15 EKG22083.1 - 5.2e-78 261.8 9.9 9.3e-78 261.0 6.8 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EKG22083.1 - 4.5e-32 109.5 2.7 4.5e-32 109.5 1.9 3.2 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EKG22083.1 - 3.7e-08 32.7 0.0 7.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EKG22083.1 - 0.023 14.3 1.3 0.023 14.3 0.9 3.1 3 0 0 3 3 3 0 Stannin transmembrane RabGAP-TBC PF00566.13 EKG22084.1 - 1.3e-35 122.8 0.0 7.6e-29 100.7 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain NTR2 PF15458.1 EKG22085.1 - 1.1e-58 198.4 16.6 2.3e-58 197.4 11.5 1.5 1 1 0 1 1 1 1 Nineteen complex-related protein 2 LSM PF01423.17 EKG22086.1 - 1.6e-18 66.0 0.2 1.8e-18 65.8 0.2 1.0 1 0 0 1 1 1 1 LSM domain APH PF01636.18 EKG22087.1 - 1.3e-39 136.4 0.0 2.1e-39 135.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EKG22087.1 - 5.4e-06 25.7 0.0 9e-06 25.0 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EKG22087.1 - 0.00023 20.7 0.0 0.00036 20.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EKG22087.1 - 0.00066 19.0 0.0 0.01 15.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EKG22087.1 - 0.0058 15.7 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.6 EKG22087.1 - 0.021 13.4 0.0 0.16 10.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) SPT2 PF08243.6 EKG22088.1 - 1e-05 25.7 24.5 1e-05 25.7 17.0 1.7 2 1 0 2 2 2 1 SPT2 chromatin protein SEEEED PF14797.1 EKG22088.1 - 0.05 13.7 9.4 0.062 13.4 6.5 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Cwf_Cwc_15 PF04889.7 EKG22088.1 - 0.22 11.2 12.9 0.24 11.0 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.8 EKG22088.1 - 1.5 8.3 19.7 1.8 8.0 13.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein BTV_NS2 PF04514.7 EKG22088.1 - 3.5 6.4 9.8 4.2 6.1 6.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spt5_N PF11942.3 EKG22088.1 - 3.5 8.2 19.9 5.2 7.7 13.8 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_60s PF00428.14 EKG22089.1 - 4.9e-29 100.5 13.9 5.8e-29 100.3 9.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 EKG22089.1 - 0.028 12.6 1.1 0.031 12.4 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3824 PF12868.2 EKG22089.1 - 0.53 11.2 3.5 0.72 10.7 2.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Sigma70_r1_1 PF03979.9 EKG22089.1 - 0.71 9.8 0.1 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Ribosomal_S19 PF00203.16 EKG22090.1 - 7.5e-34 115.1 0.3 1.2e-33 114.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Cys_Met_Meta_PP PF01053.15 EKG22092.1 - 1.4e-138 461.4 0.0 1.6e-138 461.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EKG22092.1 - 5.1e-10 38.8 0.1 7.8e-10 38.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EKG22092.1 - 2.5e-06 26.7 0.2 5.4e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EKG22092.1 - 1.2e-05 24.6 0.1 2.1e-05 23.8 0.1 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EKG22092.1 - 1.5e-05 23.9 0.2 2.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Paf1 PF03985.8 EKG22095.1 - 0.0015 17.3 4.1 0.0018 17.1 2.8 1.2 1 0 0 1 1 1 1 Paf1 CobT PF06213.7 EKG22095.1 - 0.0033 16.5 5.0 0.0039 16.3 3.5 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 EKG22095.1 - 0.0089 15.6 8.3 0.014 15.0 5.7 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Spore_coat_CotO PF14153.1 EKG22095.1 - 0.0092 15.4 4.8 0.012 15.1 3.3 1.1 1 0 0 1 1 1 1 Spore coat protein CotO SDA1 PF05285.7 EKG22095.1 - 0.01 15.1 4.8 0.012 14.8 3.3 1.1 1 0 0 1 1 1 1 SDA1 Raftlin PF15250.1 EKG22095.1 - 0.045 12.2 0.0 0.056 11.9 0.0 1.1 1 0 0 1 1 1 0 Raftlin FAM176 PF14851.1 EKG22095.1 - 0.049 13.3 5.2 0.07 12.8 3.6 1.2 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.6 EKG22095.1 - 0.09 10.6 1.3 0.1 10.4 0.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.9 EKG22095.1 - 0.1 12.6 4.1 0.15 12.0 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CENP-B_dimeris PF09026.5 EKG22095.1 - 0.17 12.1 12.7 0.34 11.1 8.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 EKG22095.1 - 0.23 9.6 8.4 0.28 9.3 5.9 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ycf1 PF05758.7 EKG22095.1 - 0.39 8.3 3.3 0.47 8.1 2.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EKG22095.1 - 0.44 9.8 9.7 0.61 9.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 EKG22095.1 - 0.52 9.8 6.4 0.7 9.3 4.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EKG22095.1 - 0.72 7.7 12.3 0.92 7.3 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Prp19_bind PF06991.6 EKG22095.1 - 1.3 8.2 13.8 1.7 7.8 9.5 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain NOA36 PF06524.7 EKG22095.1 - 1.3 8.1 5.0 1.7 7.8 3.5 1.1 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 EKG22095.1 - 1.4 6.8 6.8 1.8 6.5 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EKG22095.1 - 1.4 7.8 7.9 2 7.3 5.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prothymosin PF03247.9 EKG22095.1 - 1.8 8.7 30.0 2.6 8.2 20.8 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family TFIIF_alpha PF05793.7 EKG22095.1 - 1.9 6.7 13.0 2.6 6.3 9.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med17 PF10156.4 EKG22095.1 - 2.4 6.3 7.6 29 2.7 6.8 1.6 2 0 0 2 2 2 0 Subunit 17 of Mediator complex RRN3 PF05327.6 EKG22095.1 - 3 5.8 4.9 3.9 5.4 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 EKG22095.1 - 3.3 6.0 18.4 5.4 5.3 12.8 1.2 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 EKG22095.1 - 3.8 7.2 8.4 5.4 6.7 5.8 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Adeno_terminal PF02459.10 EKG22095.1 - 5.2 5.1 9.8 6.7 4.7 6.8 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein BSP_II PF05432.6 EKG22095.1 - 7.4 5.7 20.5 11 5.1 14.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2890 PF11081.3 EKG22095.1 - 9.9 6.1 18.2 16 5.4 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Peptidase_M35 PF02102.10 EKG22096.1 - 1.4e-44 152.2 1.3 1.7e-44 151.9 0.9 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EKG22096.1 - 2.2e-06 28.2 0.2 3.5e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EKG22096.1 - 6e-05 22.5 2.4 0.00076 18.9 1.6 2.1 1 1 0 1 1 1 1 Putative peptidase family LPAM_1 PF08139.7 EKG22096.1 - 0.29 11.4 1.9 0.55 10.5 1.3 1.5 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site INCENP_ARK-bind PF03941.10 EKG22097.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF2524 PF10732.4 EKG22097.1 - 0.13 12.3 0.1 0.37 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) LRR_8 PF13855.1 EKG22098.1 - 0.06 13.1 0.0 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat Asp PF00026.18 EKG22100.1 - 2.2e-58 197.9 3.6 2.2e-58 197.9 2.5 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EKG22100.1 - 0.00062 20.2 0.3 0.035 14.5 0.2 3.3 2 1 0 2 2 2 1 Aspartyl protease Yip1 PF04893.12 EKG22101.1 - 0.009 15.5 5.4 0.009 15.5 3.7 2.7 1 1 1 2 2 2 1 Yip1 domain CS PF04969.11 EKG22102.1 - 0.0013 19.2 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 CS domain DUF4351 PF14261.1 EKG22102.1 - 0.014 15.2 0.3 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) Spore_coat_CotO PF14153.1 EKG22102.1 - 1.3 8.4 7.6 1.7 8.0 5.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Ribosomal_60s PF00428.14 EKG22102.1 - 1.8 9.0 14.4 4.2 7.8 10.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein TRAP_alpha PF03896.11 EKG22102.1 - 2.1 7.2 12.9 3.1 6.7 8.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP_sp32 PF07222.7 EKG22102.1 - 2.8 7.0 11.5 4.1 6.5 8.0 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 BUD22 PF09073.5 EKG22102.1 - 3.3 6.6 22.9 4.3 6.2 15.9 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 EKG22102.1 - 5.8 5.3 8.6 8.3 4.8 5.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Amidase PF01425.16 EKG22103.1 - 7.7e-41 140.3 0.0 8.6e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Amidase FAD_binding_3 PF01494.14 EKG22104.1 - 2.3e-76 257.1 0.0 2.9e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EKG22104.1 - 2.7e-34 118.1 0.0 4.6e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EKG22104.1 - 9.1e-08 31.3 0.0 0.001 18.0 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG22104.1 - 1.5e-07 31.5 0.0 8e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EKG22104.1 - 7.5e-07 29.4 0.0 0.00016 21.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG22104.1 - 1.1e-05 24.0 0.1 3.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EKG22104.1 - 2.9e-05 23.1 0.1 5.8e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EKG22104.1 - 3.1e-05 23.9 0.0 0.00011 22.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EKG22104.1 - 4.4e-05 23.6 0.1 0.00014 21.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG22104.1 - 0.00012 21.3 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EKG22104.1 - 0.00054 18.9 0.0 0.0013 17.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EKG22104.1 - 0.0019 17.3 0.0 0.0042 16.2 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EKG22104.1 - 0.0057 15.8 0.0 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EKG22104.1 - 0.011 15.6 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 EKG22104.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A SE PF08491.5 EKG22104.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase XdhC_C PF13478.1 EKG22104.1 - 0.027 14.8 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 EKG22104.1 - 0.031 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EKG22104.1 - 0.039 13.7 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 EKG22104.1 - 0.053 13.7 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EKG22104.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EKG22106.1 - 3.2e-12 46.1 0.0 2.5e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EKG22106.1 - 5.5e-05 22.1 0.0 0.00015 20.7 0.0 1.7 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EKG22106.1 - 0.00014 20.9 0.1 0.00023 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EKG22106.1 - 0.0039 16.1 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EKG22106.1 - 0.11 11.0 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Polysacc_deac_1 PF01522.16 EKG22107.1 - 3e-21 75.3 0.0 6.4e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 EKG22107.1 - 0.066 11.2 0.0 0.11 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF2334 PF10096.4 EKG22107.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Oxidored_FMN PF00724.15 EKG22108.1 - 2.6e-85 286.4 0.0 4.4e-75 252.7 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Ald_Xan_dh_C2 PF02738.13 EKG22109.1 - 1.1e-178 595.0 1.7 2.5e-144 481.5 0.4 2.1 2 0 0 2 2 2 2 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EKG22109.1 - 1.3e-39 135.4 0.0 2.1e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EKG22109.1 - 1.3e-34 118.2 0.4 1.5e-33 114.8 0.0 2.5 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EKG22109.1 - 6.5e-30 103.4 0.2 1.4e-29 102.4 0.2 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EKG22109.1 - 1.1e-25 89.3 0.0 3.4e-25 87.7 0.0 2.0 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EKG22109.1 - 1.4e-08 34.3 0.0 1.4e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain UL11 PF11094.3 EKG22109.1 - 0.21 11.4 3.8 5.5 6.8 0.0 2.8 2 0 0 2 2 2 0 Membrane-associated tegument protein Fungal_trans PF04082.13 EKG22110.1 - 1.1e-45 155.5 1.1 1.7e-45 154.9 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PBP1_TM PF14812.1 EKG22110.1 - 0.98 9.7 4.2 3.3 8.0 2.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DIOX_N PF14226.1 EKG22111.1 - 1.5e-28 99.6 0.2 4.5e-28 98.1 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG22111.1 - 8.2e-23 80.5 0.0 7.8e-22 77.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 EKG22112.1 - 0.0042 15.7 0.0 0.0057 15.2 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter F-box-like PF12937.2 EKG22113.1 - 0.0041 16.8 0.2 0.019 14.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EKG22113.1 - 0.074 12.7 0.2 0.52 10.0 0.0 2.4 2 0 0 2 2 2 0 F-box domain Beta-lactamase PF00144.19 EKG22114.1 - 4.1e-25 88.4 0.0 5.2e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase DUF1965 PF09248.5 EKG22116.1 - 4.9e-30 103.2 0.2 8.2e-30 102.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxid PF01179.15 EKG22116.1 - 8.3e-17 61.0 0.0 1.1e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EKG22116.1 - 0.00039 20.4 0.0 0.00071 19.6 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cytochrom_C PF00034.16 EKG22116.1 - 0.13 13.0 1.2 0.5 11.2 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c Peptidase_S8 PF00082.17 EKG22119.1 - 2.5e-56 190.9 4.8 3.5e-56 190.4 3.3 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EKG22119.1 - 1.2e-29 101.9 1.1 2.2e-29 101.0 0.8 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain Abhydrolase_6 PF12697.2 EKG22120.1 - 1.5e-27 97.0 2.1 2.1e-27 96.4 1.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG22120.1 - 9.9e-11 41.6 0.1 1.2e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG22120.1 - 6.5e-07 29.2 0.0 4.9e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EKG22120.1 - 0.041 12.3 0.0 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family ADH_zinc_N PF00107.21 EKG22121.1 - 4.7e-21 74.6 0.5 9e-21 73.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EKG22121.1 - 4.1e-13 50.3 0.1 1.1e-12 48.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG22121.1 - 1.3e-07 31.3 0.1 1.3e-06 28.0 0.1 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain UBN2_2 PF14227.1 EKG22121.1 - 4e-05 23.1 0.1 7.1e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EKG22121.1 - 0.00047 19.7 0.2 0.00097 18.7 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EKG22121.1 - 0.015 15.0 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Aminotran_1_2 PF00155.16 EKG22122.1 - 1e-72 245.1 0.0 1.3e-72 244.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.2 EKG22122.1 - 7.5e-16 58.7 1.4 2.4e-15 57.0 0.9 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG22122.1 - 6.5e-10 38.9 0.0 2.2e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG22122.1 - 7.3e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EKG22122.1 - 0.0036 16.4 0.0 0.51 9.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Fungal_trans PF04082.13 EKG22123.1 - 2.2e-24 85.7 0.0 3.8e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HATPase_c_2 PF13581.1 EKG22123.1 - 0.12 12.1 0.1 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain GMC_oxred_N PF00732.14 EKG22127.1 - 2.1e-41 141.9 0.0 2.8e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG22127.1 - 0.0005 19.0 0.0 0.0012 17.8 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG22127.1 - 0.0027 17.7 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EKG22127.1 - 0.008 15.0 0.0 0.023 13.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EKG22127.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EKG22127.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EKG22127.1 - 0.098 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EKG22127.1 - 0.11 12.2 0.2 0.54 10.0 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HAD_2 PF13419.1 EKG22128.1 - 1.9e-41 142.1 0.0 2.2e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EKG22128.1 - 5.8e-05 23.6 0.0 0.0051 17.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EKG22128.1 - 0.0097 16.0 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 EKG22129.1 - 1.3e-42 144.0 0.6 2.5e-15 56.5 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EKG22129.1 - 7.5e-31 104.3 5.9 4.6e-06 26.1 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EKG22129.1 - 5.5e-27 93.1 6.7 0.00054 20.1 0.0 8.1 3 2 5 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG22129.1 - 1.9e-26 91.9 0.2 1.2e-07 32.0 0.0 6.3 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG22129.1 - 3e-25 85.7 0.2 0.00013 21.8 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Trm56 PF01994.11 EKG22129.1 - 0.0076 15.9 0.1 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA ribose 2'-O-methyltransferase, aTrm56 DUF1843 PF08898.5 EKG22129.1 - 0.017 15.1 1.2 9.4 6.3 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Exo_endo_phos PF03372.18 EKG22129.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Aldedh PF00171.17 EKG22130.1 - 3.1e-31 108.2 0.0 3.5e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.13 EKG22131.1 - 7e-07 29.0 7.1 1.4e-06 28.0 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EKG22131.1 - 3.7e-06 26.0 2.0 5.4e-06 25.4 0.0 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF59 PF01883.14 EKG22132.1 - 8.2e-07 28.9 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 OPT PF03169.10 EKG22134.1 - 2.6e-137 458.9 37.5 3.1e-137 458.6 26.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1412 PF07203.6 EKG22134.1 - 0.053 13.4 1.3 0.4 10.6 0.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1412) DIOX_N PF14226.1 EKG22135.1 - 3e-19 69.6 0.0 6.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EKG22135.1 - 1.1e-16 60.9 0.0 1.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA-synt_1 PF00133.17 EKG22136.1 - 2.1e-221 736.0 0.0 1.3e-220 733.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EKG22136.1 - 6.2e-33 113.7 0.2 6.2e-33 113.7 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EKG22136.1 - 1.6e-15 56.7 0.1 2.7e-06 26.3 0.0 4.8 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EKG22136.1 - 6.2e-11 41.9 4.8 2.9e-07 29.9 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EKG22136.1 - 0.016 14.3 0.0 0.044 12.9 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GvpL_GvpF PF06386.6 EKG22136.1 - 5.4 6.5 9.8 3 7.3 4.9 1.9 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Pkinase PF00069.20 EKG22137.1 - 4.2e-60 203.0 0.1 4.8e-60 202.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG22137.1 - 3.6e-20 72.1 0.0 5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG22137.1 - 9e-08 32.1 0.0 5.8e-05 22.9 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EKG22137.1 - 0.0046 16.5 0.1 0.016 14.7 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EKG22137.1 - 0.0082 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG22137.1 - 0.023 13.7 0.1 0.044 12.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_T PF00929.19 EKG22139.1 - 2.8e-24 86.2 0.0 5.8e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease NUFIP1 PF10453.4 EKG22140.1 - 7.5e-18 63.7 6.6 4.3e-17 61.3 4.5 2.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RNA_pol_Rbc25 PF08292.7 EKG22141.1 - 9.2e-36 122.7 0.2 1.4e-35 122.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EKG22141.1 - 8.7e-15 54.6 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 zf-ribbon_3 PF13248.1 EKG22142.1 - 0.77 9.0 9.3 4 6.7 6.3 2.0 1 1 0 1 1 1 0 zinc-ribbon domain PI-PLC-X PF00388.14 EKG22143.1 - 2e-61 205.6 0.0 3.2e-61 204.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EKG22143.1 - 1.4e-33 115.3 0.0 2.7e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Dehydrin PF00257.14 EKG22143.1 - 0.0016 18.7 2.5 0.024 14.9 0.9 2.4 2 0 0 2 2 2 1 Dehydrin Cupin_2 PF07883.6 EKG22144.1 - 0.0012 18.2 0.2 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EKG22144.1 - 0.033 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_7 PF12973.2 EKG22144.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.5 1 1 0 1 1 1 0 ChrR Cupin-like domain DUF3584 PF12128.3 EKG22145.1 - 0.024 11.9 48.1 0.059 10.7 33.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF641 PF04859.7 EKG22145.1 - 0.092 12.5 30.6 0.13 12.0 1.3 3.9 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) Cauli_AT PF03233.8 EKG22145.1 - 0.31 10.7 20.5 0.17 11.5 2.6 2.7 3 0 0 3 3 3 0 Aphid transmission protein RolB_RolC PF02027.12 EKG22145.1 - 9.7 5.3 14.8 0.61 9.2 0.1 3.0 2 1 1 3 3 3 0 RolB/RolC glucosidase family SET PF00856.23 EKG22146.1 - 2.4e-14 53.9 0.0 1.2e-09 38.6 0.0 2.2 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 EKG22146.1 - 3.3e-08 33.2 11.8 3.3e-08 33.2 8.2 2.2 3 0 0 3 3 3 1 MYND finger GPI-anchored PF10342.4 EKG22147.1 - 5.8e-14 52.3 0.3 5.8e-14 52.3 0.2 3.4 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CBM_48 PF02922.13 EKG22147.1 - 0.00069 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3337 PF11816.3 EKG22147.1 - 0.19 11.1 5.0 0.23 10.7 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF3080 PF11279.3 EKG22147.1 - 0.61 9.1 2.7 0.84 8.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) GPI-anchored PF10342.4 EKG22148.1 - 9.8e-20 70.8 0.8 9.8e-20 70.8 0.6 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.4 EKG22148.1 - 0.029 12.6 13.1 0.029 12.6 9.1 1.0 1 0 0 1 1 1 0 Transmembrane protein CDH PF02611.10 EKG22148.1 - 0.08 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Kei1 PF08552.6 EKG22148.1 - 2.2 7.8 13.9 4.1 7.0 9.7 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_S64 PF08192.6 EKG22148.1 - 4.9 5.3 10.2 5.4 5.2 7.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.4 EKG22148.1 - 6.7 5.4 8.5 8.2 5.1 5.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF566 PF04484.7 EKG22148.1 - 9.5 5.6 19.6 13 5.1 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) F-box-like PF12937.2 EKG22149.1 - 0.01 15.5 0.1 0.074 12.7 0.0 2.5 2 1 0 2 2 2 0 F-box-like SKG6 PF08693.5 EKG22152.1 - 0.0097 15.2 0.4 0.024 13.9 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 EKG22152.1 - 0.028 14.1 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Oleosin PF01277.12 EKG22152.1 - 0.09 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Oleosin Adeno_E3_CR2 PF02439.10 EKG22152.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 EKG22152.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Lamp PF01299.12 EKG22152.1 - 0.21 10.6 1.5 0.33 10.0 0.0 1.9 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) UQ_con PF00179.21 EKG22153.1 - 9.1e-27 93.2 0.0 1e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EKG22153.1 - 2e-06 27.6 0.0 2.8e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EKG22153.1 - 0.00021 21.1 0.1 0.00045 20.0 0.0 1.8 2 1 0 2 2 2 1 RWD domain UEV PF05743.8 EKG22153.1 - 0.0031 17.1 0.1 0.0042 16.7 0.1 1.2 1 0 0 1 1 1 1 UEV domain Ferric_reduct PF01794.14 EKG22154.1 - 1.4e-19 70.3 15.7 1.4e-19 70.3 10.9 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EKG22154.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EKG22154.1 - 0.044 13.6 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 FAD-binding domain Peroxin-13_N PF04088.8 EKG22155.1 - 1.2e-58 197.5 0.0 1.9e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EKG22155.1 - 1.5e-09 37.1 0.0 3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EKG22155.1 - 2.5e-07 29.9 0.0 5.2e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG22155.1 - 3.5e-07 29.6 0.1 6.5e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EKG22155.1 - 0.018 15.2 0.1 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Pex2_Pex12 PF04757.9 EKG22155.1 - 0.1 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region DUF2401 PF10287.4 EKG22156.1 - 3.8e-54 183.6 0.3 6.2e-54 182.9 0.2 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EKG22156.1 - 8.7e-17 61.0 0.0 2.3e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SelP_N PF04592.9 EKG22156.1 - 0.093 12.1 6.2 0.18 11.1 4.3 1.4 1 1 0 1 1 1 0 Selenoprotein P, N terminal region Ribosomal_S13_N PF08069.7 EKG22157.1 - 6.2e-29 99.6 0.3 1.1e-28 98.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EKG22157.1 - 5.5e-22 77.3 0.0 8.1e-22 76.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EKG22157.1 - 0.016 14.9 0.1 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.8 EKG22158.1 - 7.6e-06 25.3 0.1 1.1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif DUF3602 PF12223.3 EKG22159.1 - 2.2e-13 50.3 15.4 1.1e-08 35.2 4.6 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Sporozoite_P67 PF05642.6 EKG22159.1 - 1 7.1 4.2 1.2 6.9 2.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ZZ PF00569.12 EKG22160.1 - 0.048 13.2 14.7 0.11 12.1 10.2 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type CytochromB561_N PF09786.4 EKG22161.1 - 2.2 6.6 9.4 2.9 6.2 6.5 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal UQ_con PF00179.21 EKG22166.1 - 1.1e-41 141.5 0.0 1.9e-29 101.8 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 EKG22166.1 - 0.022 14.6 0.0 0.28 11.0 0.0 2.5 1 1 0 1 1 1 0 RWD domain RE_XamI PF09572.5 EKG22166.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 XamI restriction endonuclease UEV PF05743.8 EKG22166.1 - 0.026 14.2 0.0 0.092 12.4 0.0 1.9 3 0 0 3 3 3 0 UEV domain Sybindin PF04099.7 EKG22167.1 - 4.8e-38 130.0 0.0 5.5e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EKG22167.1 - 1.3e-08 34.7 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VWA_2 PF13519.1 EKG22168.1 - 1.3e-13 51.3 0.0 1.6e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EKG22168.1 - 1.5e-08 34.4 0.1 2e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EKG22168.1 - 1.7e-05 24.5 0.1 2.9e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EKG22168.1 - 0.027 14.0 0.4 0.074 12.6 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Nbl1_Borealin_N PF10444.4 EKG22169.1 - 7.2e-21 73.3 2.7 1.1e-20 72.6 1.9 1.3 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal FAD_binding_2 PF00890.19 EKG22171.1 - 7.6e-83 278.6 0.7 9.2e-83 278.4 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EKG22171.1 - 7.4e-21 73.7 0.4 6e-19 67.6 0.0 3.0 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EKG22171.1 - 1.1e-11 44.2 0.9 9.2e-11 41.2 0.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EKG22171.1 - 7.1e-10 38.5 0.3 2.2e-09 36.8 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG22171.1 - 1.1e-08 34.9 0.1 1.5e-07 31.3 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EKG22171.1 - 5.6e-08 32.9 0.0 4.1e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EKG22171.1 - 1.6e-06 26.8 0.5 0.0019 16.7 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EKG22171.1 - 8.8e-06 24.9 0.2 0.005 15.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EKG22171.1 - 0.00012 21.1 0.5 0.0085 15.0 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EKG22171.1 - 0.00074 19.6 0.5 0.0029 17.6 0.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG22171.1 - 0.0021 17.8 0.2 0.014 15.1 0.1 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EKG22171.1 - 0.005 15.9 0.4 0.016 14.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EKG22171.1 - 0.0073 15.4 0.1 5 6.0 0.0 3.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EKG22171.1 - 0.042 13.5 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EKG22171.1 - 0.13 11.1 0.1 1.1 8.0 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EKG22171.1 - 0.72 10.3 3.5 6.4 7.2 0.5 2.9 2 1 1 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EKG22172.1 - 2e-33 115.6 0.0 2.1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EKG22173.1 - 6.2e-06 25.1 0.0 8.1e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family p450 PF00067.17 EKG22174.1 - 1.8e-51 175.1 0.0 2.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG22176.1 - 8.4e-30 103.6 0.0 1e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EKG22181.1 - 0.076 11.6 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family E1-E2_ATPase PF00122.15 EKG22182.1 - 1.3e-49 168.2 0.1 8.2e-49 165.7 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EKG22182.1 - 2e-41 142.8 0.3 4.6e-41 141.5 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EKG22182.1 - 4.3e-36 122.8 0.0 1.3e-10 41.2 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EKG22182.1 - 2.1e-17 63.9 0.0 6.5e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EKG22182.1 - 1.1e-05 25.1 0.6 0.00041 20.0 0.6 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4140 PF13600.1 EKG22183.1 - 0.0024 18.2 1.3 0.0029 18.0 0.9 1.2 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) Med9 PF07544.8 EKG22183.1 - 0.034 13.8 0.4 0.072 12.8 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Cep57_CLD_2 PF14197.1 EKG22183.1 - 0.067 13.1 2.6 0.1 12.5 1.8 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 AP_endonuc_2 PF01261.19 EKG22183.1 - 0.11 11.7 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF1192 PF06698.6 EKG22183.1 - 0.11 12.2 2.5 0.21 11.4 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) CcdA PF07362.7 EKG22183.1 - 0.28 11.0 1.9 0.84 9.5 0.0 2.0 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Mito_fiss_reg PF05308.6 EKG22183.1 - 0.43 9.9 2.9 0.48 9.7 1.5 1.5 1 1 1 2 2 2 0 Mitochondrial fission regulator PMT PF02366.13 EKG22184.1 - 6.3e-84 281.1 20.3 1.1e-83 280.3 14.1 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EKG22184.1 - 1.8e-17 63.4 0.9 4.9e-17 62.0 0.2 1.8 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 EKG22184.1 - 9.9e-05 22.2 12.5 9.9e-05 22.2 8.7 3.2 3 1 1 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Orai-1 PF07856.7 EKG22184.1 - 0.62 9.5 4.7 2.1 7.8 1.1 2.4 2 0 0 2 2 2 0 Mediator of CRAC channel activity UAA PF08449.6 EKG22185.1 - 7.8e-80 268.0 10.2 1.1e-79 267.5 7.1 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EKG22185.1 - 0.00016 20.8 0.6 0.00016 20.8 0.4 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EKG22185.1 - 0.00032 20.3 8.2 0.00032 20.3 5.7 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 EKG22185.1 - 0.011 15.9 16.7 0.3 11.2 2.8 2.8 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF373 PF04123.8 EKG22185.1 - 0.21 10.5 2.5 0.15 11.0 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) EamA PF00892.15 EKG22185.1 - 2.9 7.9 18.1 0.84 9.6 2.9 2.7 2 1 0 2 2 2 0 EamA-like transporter family WD40 PF00400.27 EKG22186.1 - 5.3e-13 48.2 0.2 0.71 9.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_L3 PF00297.17 EKG22187.1 - 3.4e-119 397.0 7.3 4.1e-119 396.7 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 DUF3887 PF13026.1 EKG22187.1 - 0.31 11.3 2.6 1.1 9.6 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3887) FAD_binding_2 PF00890.19 EKG22188.1 - 3e-125 418.3 1.9 3.8e-125 418.0 1.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EKG22188.1 - 4.2e-47 159.2 0.8 6.2e-47 158.6 0.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EKG22188.1 - 9.8e-07 28.8 0.0 0.00032 20.6 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EKG22188.1 - 7.7e-06 25.1 0.0 0.014 14.4 0.0 2.8 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EKG22188.1 - 0.00011 21.2 1.1 0.11 11.3 0.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EKG22188.1 - 0.00015 20.8 0.1 0.0048 15.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EKG22188.1 - 0.0049 15.9 0.1 0.011 14.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Cpn60_TCP1 PF00118.19 EKG22189.1 - 2.7e-135 451.7 11.3 3.3e-135 451.4 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.24 EKG22190.1 - 9e-41 139.1 0.0 1.6e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG22190.1 - 6.8e-06 26.2 0.0 0.00066 19.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKG22190.1 - 4.8e-05 23.1 0.1 0.00029 20.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EKG22190.1 - 0.00022 21.2 0.0 0.00091 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EKG22190.1 - 0.00027 20.9 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EKG22190.1 - 0.0017 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EKG22190.1 - 0.0038 18.0 0.1 0.015 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG22190.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 EKG22190.1 - 0.015 14.3 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EKG22190.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EKG22190.1 - 0.036 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EKG22190.1 - 0.04 13.8 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EKG22190.1 - 0.044 13.4 0.8 10 5.7 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase RNA_helicase PF00910.17 EKG22190.1 - 0.049 13.7 0.0 0.16 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EKG22190.1 - 0.067 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EKG22190.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EKG22190.1 - 0.087 13.1 0.1 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EKG22190.1 - 0.088 12.3 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EKG22190.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EKG22190.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EKG22190.1 - 0.13 11.4 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EKG22190.1 - 0.15 11.4 0.2 0.5 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.1 EKG22191.1 - 0.29 11.5 18.0 0.086 13.2 2.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EKG22191.1 - 5.3 7.5 11.9 1.6 9.2 2.7 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type A_deaminase PF00962.17 EKG22192.1 - 6.7e-113 376.9 0.2 8.9e-113 376.5 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Mito_carr PF00153.22 EKG22193.1 - 1.4e-48 162.5 9.1 9.5e-19 66.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_fiss_reg PF05308.6 EKG22194.1 - 0.15 11.4 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Aminotran_1_2 PF00155.16 EKG22195.1 - 5.7e-12 45.2 0.0 7e-12 44.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EKG22195.1 - 4.5e-09 35.3 0.0 7e-09 34.7 0.0 1.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DAD PF02109.11 EKG22196.1 - 1.7e-12 47.3 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 DAD family gpUL132 PF11359.3 EKG22196.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.4 2 0 0 2 2 2 0 Glycoprotein UL132 DUF3597 PF12200.3 EKG22196.1 - 0.65 10.3 6.2 0.12 12.7 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) DUF1180 PF06679.7 EKG22196.1 - 2 8.2 9.4 0.7 9.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Tmemb_14 PF03647.8 EKG22197.1 - 9.7e-26 90.0 6.9 1.2e-25 89.6 4.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1275 PF06912.6 EKG22197.1 - 0.0037 16.5 0.4 0.0057 15.8 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) RTC4 PF14474.1 EKG22198.1 - 1e-25 90.0 0.0 1.7e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain GAGA PF09237.6 EKG22198.1 - 0.016 14.7 0.3 0.035 13.7 0.2 1.5 1 0 0 1 1 1 0 GAGA factor RTC PF01137.16 EKG22199.1 - 6.5e-36 123.2 0.1 9.1e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EKG22199.1 - 1.2e-30 105.5 0.0 2.2e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RhoGAP PF00620.22 EKG22200.1 - 2.8e-37 127.6 0.0 6.9e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EKG22200.1 - 7.8e-29 99.5 36.9 1.4e-11 44.2 3.0 5.1 5 0 0 5 5 5 4 LIM domain DUF4243 PF14027.1 EKG22201.1 - 7.2e-71 239.3 0.0 9.1e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4603 PF15376.1 EKG22201.1 - 0.1 9.7 0.1 0.14 9.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) tRNA-synt_2 PF00152.15 EKG22202.1 - 1.1e-74 251.2 0.0 1.8e-74 250.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EKG22202.1 - 6e-15 54.8 0.0 8.3e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EKG22202.1 - 1.8e-06 27.7 0.0 4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EKG22202.1 - 0.0019 17.4 0.1 0.25 10.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.3 EKG22202.1 - 2.6 6.6 9.8 4.2 6.0 6.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1682 PF07946.9 EKG22202.1 - 6.8 5.4 11.1 11 4.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) HECT_2 PF09814.4 EKG22203.1 - 1.1e-28 100.0 0.0 4.9e-20 71.5 0.0 2.0 2 0 0 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF2296 PF10058.4 EKG22203.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C2H2 PF00096.21 EKG22204.1 - 0.0019 18.4 4.1 0.0019 18.4 2.9 2.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type DUF3245 PF11595.3 EKG22204.1 - 0.17 12.1 1.2 0.63 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) zf-C2H2_4 PF13894.1 EKG22204.1 - 9.6 6.8 17.3 0.65 10.4 1.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF1771 PF08590.5 EKG22206.1 - 5.2e-14 51.9 10.7 5.2e-14 51.9 7.4 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 EKG22206.1 - 4.1e-11 42.2 6.1 4.1e-05 23.1 1.5 2.4 1 1 1 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 EKG22206.1 - 5.4e-09 36.1 0.0 2.3e-08 34.1 0.0 2.1 1 0 0 1 1 1 1 Smr domain zf-C3H1 PF10650.4 EKG22206.1 - 0.28 10.7 4.5 0.69 9.4 0.1 2.5 2 1 0 2 2 2 0 Putative zinc-finger domain zf-CCCH PF00642.19 EKG22207.1 - 2.1e-21 75.1 33.4 6.4e-05 22.5 0.4 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EKG22207.1 - 0.42 10.6 0.1 0.42 10.6 0.0 5.5 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Vps53_N PF04100.7 EKG22208.1 - 1.4e-106 356.5 4.6 1.4e-106 356.5 3.2 1.5 2 0 0 2 2 2 1 Vps53-like, N-terminal Glyco_hydro_18 PF00704.23 EKG22208.1 - 1e-75 255.3 0.0 1.6e-75 254.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF2450 PF10475.4 EKG22208.1 - 1.7e-08 33.7 2.8 3.3e-08 32.7 1.9 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EKG22208.1 - 0.0051 16.6 3.1 0.0057 16.5 0.1 2.6 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 Zw10 PF06248.8 EKG22208.1 - 0.014 13.6 4.5 0.028 12.5 3.1 1.4 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF3142 PF11340.3 EKG22208.1 - 0.042 13.5 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) SNARE_assoc PF09335.6 EKG22209.1 - 1e-11 45.0 9.2 1e-11 45.0 6.4 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein Pox_A14 PF05767.7 EKG22209.1 - 0.0063 16.4 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 PgaD PF13994.1 EKG22209.1 - 0.043 13.2 1.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 PgaD-like protein DUF1049 PF06305.6 EKG22209.1 - 0.11 12.0 0.0 0.11 12.0 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) DUF3147 PF11345.3 EKG22209.1 - 0.43 10.6 6.1 0.056 13.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) DUF4191 PF13829.1 EKG22209.1 - 3.4 6.7 4.7 2 7.4 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Sec1 PF00995.18 EKG22210.1 - 4.7e-112 375.4 0.0 6.2e-112 375.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.1 EKG22211.1 - 5.7e-42 143.8 0.0 1.9e-35 122.4 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EKG22211.1 - 8.6e-19 67.7 0.0 1.5e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EKG22211.1 - 8e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EKG22211.1 - 0.0013 17.5 0.1 0.0098 14.6 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Sporozoite_P67 PF05642.6 EKG22211.1 - 0.05 11.4 0.2 0.073 10.9 0.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_3 PF01494.14 EKG22212.1 - 4.5e-23 81.8 0.1 1.5e-11 43.9 0.1 2.2 1 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EKG22212.1 - 0.0014 18.5 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG22212.1 - 0.0095 14.8 1.5 0.49 9.2 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EKG22212.1 - 0.094 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.5 EKG22212.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase zf-RING_2 PF13639.1 EKG22213.1 - 4.9e-15 55.0 6.1 7.8e-15 54.4 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EKG22213.1 - 4.5e-09 36.2 1.5 8.7e-09 35.3 1.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EKG22213.1 - 2.6e-08 33.3 3.3 4.7e-08 32.5 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EKG22213.1 - 6.7e-07 28.9 3.7 1.1e-06 28.2 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EKG22213.1 - 8.8e-07 28.8 4.7 1.5e-06 28.1 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EKG22213.1 - 4.1e-06 26.3 2.0 6.7e-06 25.6 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EKG22213.1 - 0.0007 19.3 2.5 0.0018 18.0 1.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EKG22213.1 - 0.0014 18.1 6.5 0.0024 17.4 4.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EKG22213.1 - 0.027 14.4 3.4 0.078 12.9 2.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EKG22213.1 - 0.033 14.2 5.8 0.061 13.3 4.0 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EKG22213.1 - 0.036 13.7 5.7 0.068 12.8 4.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 EKG22213.1 - 0.07 12.8 2.4 0.15 11.7 1.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF3245 PF11595.3 EKG22213.1 - 0.25 11.5 6.2 0.17 12.1 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) zf-C3HC4_4 PF15227.1 EKG22213.1 - 0.28 11.0 4.6 0.62 9.9 3.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EKG22213.1 - 1.3 8.8 7.3 9.7 6.0 5.0 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.16 EKG22214.1 - 1.1e-49 168.6 0.8 1.2e-49 168.4 0.6 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Gal_mutarotas_2 PF13802.1 EKG22215.1 - 0.25 11.2 2.2 1.7 8.5 0.2 2.2 2 0 0 2 2 2 0 Galactose mutarotase-like CDP-OH_P_transf PF01066.16 EKG22216.1 - 1.3e-13 51.1 10.8 1.3e-13 51.1 7.5 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4199 PF13858.1 EKG22217.1 - 0.0057 16.5 0.0 0.0064 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Virul_fac_BrkB PF03631.10 EKG22217.1 - 0.039 13.2 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Pkinase PF00069.20 EKG22218.1 - 6e-72 241.9 0.0 7.8e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG22218.1 - 7e-36 123.6 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 EKG22218.1 - 0.00081 18.7 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EKG22218.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EKG22218.1 - 0.0041 16.2 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Bromodomain PF00439.20 EKG22219.1 - 2.5e-32 110.6 1.1 5.8e-18 64.6 0.4 2.6 2 0 0 2 2 2 2 Bromodomain DUF1720 PF08226.6 EKG22220.1 - 0.95 9.5 13.5 1.3 9.0 9.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) zf-Di19 PF05605.7 EKG22221.1 - 0.00082 19.4 0.5 0.0015 18.6 0.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EKG22221.1 - 0.46 10.9 2.6 1.3 9.4 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type HSP70 PF00012.15 EKG22222.1 - 8.3e-234 777.0 9.5 9.2e-234 776.8 6.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EKG22222.1 - 9.8e-16 57.2 0.2 6.5e-15 54.5 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EKG22222.1 - 3.5e-05 23.5 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 EKG22222.1 - 0.033 13.1 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 0 StbA protein MRC1 PF09444.5 EKG22222.1 - 0.046 14.0 2.7 0.14 12.5 1.9 1.8 1 0 0 1 1 1 0 MRC1-like domain MatP PF06303.7 EKG22222.1 - 8 6.3 8.3 3.4 7.5 0.1 3.4 3 1 0 4 4 4 0 Organiser of macrodomain of Terminus of chromosome Peptidase_M1 PF01433.15 EKG22223.1 - 1.1e-06 27.9 0.0 0.048 12.7 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 HEAT_2 PF13646.1 EKG22223.1 - 1.5e-05 25.1 0.3 0.3 11.4 0.0 3.5 4 0 0 4 4 4 2 HEAT repeats SAS4 PF15460.1 EKG22224.1 - 4.7e-36 122.6 4.7 9e-36 121.8 3.2 1.5 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 PX PF00787.19 EKG22225.1 - 1.1e-20 73.5 0.0 1.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 PX domain Acid_PPase PF12689.2 EKG22225.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Sel1 PF08238.7 EKG22229.1 - 3.2e-34 116.6 27.8 2.4e-05 24.8 0.0 7.6 6 1 1 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.10 EKG22230.1 - 3.6e-293 972.7 0.0 4.7e-293 972.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EKG22230.1 - 1.2e-17 64.2 5.7 7.1e-17 61.7 4.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG22230.1 - 6.6e-16 58.8 0.0 1e-14 54.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EKG22230.1 - 7.6e-11 41.6 0.0 5e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EKG22230.1 - 1.3e-05 24.5 0.0 0.00026 20.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EKG22230.1 - 0.00019 21.1 0.0 0.0061 16.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 WD40 PF00400.27 EKG22231.1 - 7.7e-05 22.4 3.5 0.0033 17.2 0.0 4.1 6 0 0 6 6 6 2 WD domain, G-beta repeat adh_short PF00106.20 EKG22232.1 - 1.2e-13 51.2 0.0 2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG22232.1 - 1.6e-05 24.6 0.1 2.4e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG22232.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG22232.1 - 0.041 13.8 0.3 0.065 13.2 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EKG22232.1 - 0.047 13.1 0.0 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EKG22232.1 - 0.18 11.8 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Abhydrolase_4 PF08386.5 EKG22233.1 - 8e-22 77.0 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EKG22233.1 - 2e-16 60.2 0.0 2.1e-07 30.7 0.0 3.4 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EKG22233.1 - 3.2e-07 30.4 0.0 1.2e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG22233.1 - 0.00062 19.5 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family RRM_1 PF00076.17 EKG22234.1 - 1e-24 85.9 0.1 1.3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EKG22234.1 - 3.2e-17 62.2 0.0 4.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG22234.1 - 1.9e-10 40.4 0.0 2.5e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyrophosphatase PF00719.14 EKG22236.1 - 2.8e-53 179.5 0.1 3.2e-53 179.3 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 EKG22237.1 - 7.8e-17 60.9 0.6 1.2e-16 60.3 0.4 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Sec20 PF03908.8 EKG22238.1 - 8.4e-16 57.4 1.0 8.4e-16 57.4 0.7 1.9 2 0 0 2 2 2 1 Sec20 GDPD PF03009.12 EKG22241.1 - 1.1e-38 133.2 0.0 1.4e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EKG22241.1 - 3.6e-05 23.8 0.4 0.00011 22.2 0.1 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF187 PF02638.10 EKG22241.1 - 0.015 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 AP_endonuc_2 PF01261.19 EKG22241.1 - 0.14 11.4 0.0 0.55 9.4 0.0 1.9 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Thioredoxin_4 PF13462.1 EKG22242.1 - 1.1e-08 35.3 0.0 2.1e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EKG22242.1 - 0.016 14.7 1.7 0.35 10.3 0.1 2.7 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.1 EKG22242.1 - 0.043 14.0 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DPPIV_N PF00930.16 EKG22243.1 - 6.8e-109 363.6 1.2 1.1e-108 363.0 0.8 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EKG22243.1 - 6e-55 185.7 2.9 1e-54 185.0 2.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG22243.1 - 3.9e-10 39.6 0.3 7.9e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EKG22243.1 - 2.4e-07 30.4 2.8 1e-06 28.3 1.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EKG22243.1 - 3.5e-07 30.3 0.6 2.3e-06 27.6 0.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EKG22243.1 - 0.014 14.6 0.0 0.071 12.3 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family PD40 PF07676.7 EKG22243.1 - 0.046 13.4 3.1 1 9.0 0.1 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SHS2_Rpb7-N PF03876.12 EKG22244.1 - 1.8e-14 53.6 0.0 3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EKG22244.1 - 5.1e-11 42.4 0.0 9.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EKG22244.1 - 0.00048 20.3 0.0 0.00077 19.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 DUF962 PF06127.6 EKG22245.1 - 3.9e-25 87.5 3.1 5.7e-25 87.0 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Dynamin_M PF01031.15 EKG22246.1 - 4.5e-114 380.2 0.0 7.8e-114 379.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EKG22246.1 - 3.6e-55 186.3 2.5 7.1e-55 185.3 0.0 2.5 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EKG22246.1 - 2.1e-33 114.0 3.2 5.6e-33 112.7 2.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EKG22246.1 - 0.00059 19.7 0.2 0.0074 16.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKG22246.1 - 0.012 16.1 0.0 0.041 14.3 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 EKG22246.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Baculo_p74 PF04583.7 EKG22246.1 - 0.17 11.0 0.1 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Baculoviridae p74 conserved region Ank_2 PF12796.2 EKG22247.1 - 1.2e-11 44.8 3.0 4.2e-06 27.0 0.7 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) AAA_5 PF07728.9 EKG22247.1 - 6.9e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank PF00023.25 EKG22247.1 - 6.1e-05 22.6 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat AAA_2 PF07724.9 EKG22247.1 - 7.2e-05 22.7 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EKG22247.1 - 0.00029 21.0 0.1 0.00087 19.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EKG22247.1 - 0.00053 19.8 0.1 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Torsin Ank_4 PF13637.1 EKG22247.1 - 0.0026 18.2 0.2 0.68 10.5 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG22247.1 - 0.0029 17.7 0.2 0.7 10.3 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat ClpB_D2-small PF10431.4 EKG22247.1 - 0.0072 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_6 PF12774.2 EKG22247.1 - 0.0092 15.5 0.0 0.38 10.2 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 PCI PF01399.22 EKG22248.1 - 8.2e-14 51.7 0.0 3.8e-13 49.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain TPR_19 PF14559.1 EKG22248.1 - 0.0021 18.3 4.9 0.43 10.9 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 EKG22248.1 - 0.0075 15.6 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Apc3 PF12895.2 EKG22248.1 - 0.02 15.0 0.1 2.4 8.3 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 CbbQ_C PF08406.5 EKG22248.1 - 0.029 14.3 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal TPR_14 PF13428.1 EKG22248.1 - 0.12 13.1 4.2 21 6.1 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TFIIF_beta PF02270.10 EKG22249.1 - 3.2e-53 181.3 0.5 3.8e-53 181.0 0.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Tau95 PF09734.4 EKG22249.1 - 0.0064 15.8 0.0 0.011 15.0 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit DDE_Tnp_IS66_C PF13817.1 EKG22249.1 - 0.58 10.2 3.2 3.3 7.8 0.0 3.2 3 0 0 3 3 3 0 IS66 C-terminal element DUF4545 PF15078.1 EKG22250.1 - 0.00044 19.2 0.3 0.00046 19.2 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4545) BNR PF02012.15 EKG22252.1 - 5.9e-09 34.4 41.6 0.31 11.0 0.5 11.2 11 0 0 11 11 11 6 BNR/Asp-box repeat PSII_BNR PF14870.1 EKG22252.1 - 8.9e-06 24.9 8.7 0.0002 20.4 0.0 4.8 5 1 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 DUF1282 PF06930.7 EKG22252.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DctQ PF04290.7 EKG22252.1 - 0.34 10.6 0.8 0.52 10.0 0.5 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Abhydrolase_6 PF12697.2 EKG22254.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UBA_2 PF08587.6 EKG22254.1 - 0.024 14.8 0.1 0.075 13.2 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Tic20 PF09685.5 EKG22254.1 - 0.15 12.0 4.7 0.29 11.1 3.2 1.3 1 0 0 1 1 1 0 Tic20-like protein Mt_ATP-synt_B PF05405.9 EKG22255.1 - 8.8e-43 145.5 7.2 9.8e-43 145.4 5.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) CK2S PF15011.1 EKG22255.1 - 0.083 12.6 3.3 0.082 12.6 0.9 1.8 1 1 1 2 2 2 0 Casein Kinase 2 substrate Tcp11 PF05794.8 EKG22255.1 - 0.1 11.3 6.0 0.12 11.0 4.2 1.1 1 0 0 1 1 1 0 T-complex protein 11 DUF1539 PF07560.6 EKG22255.1 - 0.17 11.7 2.0 0.33 10.8 1.4 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) Rep_trans PF02486.14 EKG22255.1 - 0.18 11.2 3.6 0.35 10.3 2.2 1.7 1 1 0 1 1 1 0 Replication initiation factor Dak2 PF02734.12 EKG22255.1 - 0.25 11.0 4.2 0.25 10.9 0.7 2.0 1 1 1 2 2 2 0 DAK2 domain DASH_Duo1 PF08651.5 EKG22255.1 - 0.28 10.7 5.4 2 8.0 0.1 3.1 1 1 2 3 3 3 0 DASH complex subunit Duo1 FAM74 PF15026.1 EKG22255.1 - 0.31 10.6 2.4 0.57 9.8 0.2 2.0 1 1 1 2 2 2 0 FAM74 protein Phage_lambd_GpG PF06894.6 EKG22255.1 - 0.34 10.5 3.7 0.2 11.3 0.3 2.0 1 1 1 2 2 2 0 Bacteriophage lambda minor tail protein (GpG) Herpes_UL95 PF03038.9 EKG22255.1 - 0.57 9.0 3.2 0.69 8.7 2.2 1.1 1 0 0 1 1 1 0 UL95 family Spore_III_AB PF09548.5 EKG22255.1 - 1.3 8.7 6.0 3.2 7.4 3.7 1.9 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AAA_23 PF13476.1 EKG22255.1 - 2.1 8.6 6.5 2.9 8.1 4.5 1.2 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EKG22255.1 - 5.6 7.1 11.6 5.1 7.3 2.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CBF PF03914.12 EKG22256.1 - 7e-47 158.9 0.0 2.1e-46 157.3 0.0 1.9 2 0 0 2 2 2 1 CBF/Mak21 family zf-CCCH PF00642.19 EKG22257.1 - 4.9e-09 35.6 27.5 3.6e-06 26.5 0.5 4.9 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sel1 PF08238.7 EKG22258.1 - 2.9e-11 43.6 0.2 1.5e-07 31.8 0.2 2.5 2 0 0 2 2 2 2 Sel1 repeat TPR_6 PF13174.1 EKG22258.1 - 0.077 13.4 0.1 0.68 10.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat bZIP_Maf PF03131.12 EKG22260.1 - 6.6e-08 32.7 15.0 6.6e-08 32.7 10.4 2.8 3 1 1 4 4 4 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EKG22260.1 - 1e-06 28.4 13.9 3.9e-06 26.5 9.6 2.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EKG22260.1 - 1.8e-06 27.7 14.0 1.8e-06 27.7 9.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor Peptidase_S9 PF00326.16 EKG22261.1 - 2.9e-50 170.4 0.3 5.2e-50 169.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EKG22261.1 - 3e-09 36.7 0.4 6.8e-09 35.6 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 EKG22261.1 - 8.2e-07 28.5 0.1 0.0015 18.1 0.0 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 EKG22261.1 - 2.7e-05 24.1 0.3 6.9e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EKG22261.1 - 0.0032 16.0 0.0 0.027 12.9 0.0 2.0 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) DPPIV_N PF00930.16 EKG22261.1 - 0.008 14.8 0.0 0.073 11.6 0.0 2.4 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cupin_3 PF05899.7 EKG22261.1 - 0.063 12.6 0.1 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Candida_ALS_N PF11766.3 EKG22261.1 - 0.14 11.0 0.1 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Cell-wall agglutinin N-terminal ligand-sugar binding DUF2920 PF11144.3 EKG22261.1 - 0.19 10.7 0.1 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Pkinase PF00069.20 EKG22262.1 - 6e-39 133.7 0.0 4e-22 78.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG22262.1 - 3.1e-15 55.9 0.0 1.8e-14 53.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EKG22262.1 - 1.6e-06 28.0 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EKG22262.1 - 0.014 14.3 0.0 0.066 12.1 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pox_P4B PF03292.9 EKG22262.1 - 0.043 11.7 0.0 0.06 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Methyltransf_31 PF13847.1 EKG22263.1 - 1.6e-17 63.5 0.0 2.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG22263.1 - 2.7e-17 62.9 0.0 3.8e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG22263.1 - 1.4e-16 61.0 0.0 2.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EKG22263.1 - 5.5e-16 58.8 0.0 8.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG22263.1 - 6.3e-16 58.6 0.0 9.4e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EKG22263.1 - 5.6e-12 45.9 0.0 9.2e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EKG22263.1 - 3.5e-09 36.2 0.0 5.7e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EKG22263.1 - 5.3e-08 32.6 0.0 7.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EKG22263.1 - 1.9e-07 31.1 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG22263.1 - 4.4e-07 29.2 0.0 1.2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EKG22263.1 - 3.5e-06 26.5 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EKG22263.1 - 2.2e-05 23.6 0.0 3.1e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 EKG22263.1 - 3.7e-05 23.3 0.0 5.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) TPMT PF05724.6 EKG22263.1 - 0.00015 21.2 0.0 0.0003 20.2 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 EKG22263.1 - 0.0003 20.4 0.0 0.00042 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EKG22263.1 - 0.0025 16.5 0.0 0.0033 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EKG22263.1 - 0.0039 16.2 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EKG22263.1 - 0.0082 15.2 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EKG22263.1 - 0.014 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CheR PF01739.13 EKG22263.1 - 0.016 14.4 0.0 2.9 7.1 0.0 2.2 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Nol1_Nop2_Fmu PF01189.12 EKG22263.1 - 0.018 14.4 0.0 0.19 11.0 0.0 2.0 1 1 1 2 2 2 0 NOL1/NOP2/sun family DREV PF05219.7 EKG22263.1 - 0.019 13.8 0.0 0.05 12.4 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase FmrO PF07091.6 EKG22263.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MetW PF07021.7 EKG22263.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW zf-DHHC PF01529.15 EKG22264.1 - 1.4e-36 125.4 1.2 2e-36 124.9 0.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EKG22264.1 - 0.13 12.1 12.2 1 9.1 6.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.16 EKG22264.1 - 10 6.1 11.9 31 4.5 8.2 1.8 1 1 0 1 1 1 0 FYVE zinc finger Glyco_transf_22 PF03901.12 EKG22265.1 - 1.8e-41 142.5 18.3 2.3e-41 142.1 12.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MFS_1 PF07690.11 EKG22267.1 - 9.5e-46 156.1 61.4 5.4e-45 153.6 41.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EKG22267.1 - 1.5e-18 66.3 17.7 1.5e-18 66.3 12.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EKG22267.1 - 1.3e-15 56.9 17.9 1.3e-15 56.9 12.4 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3453 PF11935.3 EKG22268.1 - 3.7e-76 255.7 0.1 5.6e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Coiled-coil_56 PF09813.4 EKG22269.1 - 0.00022 21.1 0.0 0.00023 21.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 MFS_1 PF07690.11 EKG22270.1 - 8.8e-32 110.1 26.1 1.8e-31 109.1 17.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily FSH1 PF03959.8 EKG22271.1 - 1.2e-26 93.4 0.0 1.6e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EKG22271.1 - 0.0022 17.9 6.0 0.01 15.7 4.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EKG22271.1 - 0.11 11.9 0.1 1.7 8.0 0.0 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.20 EKG22273.1 - 6.1e-63 212.3 0.1 1.1e-39 136.1 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EKG22273.1 - 2e-28 99.2 0.0 5.1e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EKG22273.1 - 9.2e-13 48.1 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EKG22273.1 - 5.6e-07 28.7 0.0 2.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EKG22273.1 - 1.4e-06 28.2 0.0 0.0018 18.0 0.1 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS_9 PF13426.1 EKG22273.1 - 0.0027 18.0 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EKG22273.1 - 0.013 15.2 0.0 0.046 13.4 0.0 1.9 2 0 0 2 2 2 0 PAS fold Kdo PF06293.9 EKG22273.1 - 0.017 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_11 PF14598.1 EKG22273.1 - 0.024 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.5 EKG22273.1 - 0.025 14.5 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 PAS fold Seadorna_VP7 PF07387.6 EKG22273.1 - 0.088 11.6 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RNA_pol_Rpb4 PF03874.11 EKG22274.1 - 1.7e-18 66.7 0.1 1.8e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Tenui_PVC2 PF06656.6 EKG22274.1 - 0.0046 14.8 0.2 0.0051 14.6 0.1 1.0 1 0 0 1 1 1 1 Tenuivirus PVC2 protein DUF4149 PF13664.1 EKG22275.1 - 1.3e-17 63.6 2.3 3.3e-17 62.4 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2417 PF10329.4 EKG22278.1 - 6.7e-88 294.0 0.4 8.9e-88 293.5 0.3 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EKG22278.1 - 5.2e-08 33.0 0.2 1e-07 32.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3357 PF11837.3 EKG22278.1 - 0.072 12.9 3.1 0.15 11.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) DUF4267 PF14087.1 EKG22278.1 - 1.2 8.7 7.3 1.3 8.6 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4267) RecO_N PF11967.3 EKG22280.1 - 0.11 12.3 0.4 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Recombination protein O N terminal Cation_efflux PF01545.16 EKG22282.1 - 2e-77 260.0 5.7 6.7e-77 258.3 4.0 1.7 1 1 0 1 1 1 1 Cation efflux family DUF2235 PF09994.4 EKG22285.1 - 8e-50 169.7 0.1 1.2e-49 169.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 EKG22285.1 - 8.9e-07 29.4 0.0 2.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EKG22285.1 - 1.3e-05 25.1 0.0 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EKG22285.1 - 4.2e-05 22.8 0.0 8.2e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EKG22285.1 - 0.00034 20.1 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain FSH1 PF03959.8 EKG22285.1 - 0.00093 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Septin PF00735.13 EKG22285.1 - 0.005 15.9 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Septin AAA_17 PF13207.1 EKG22285.1 - 0.0057 17.4 0.1 0.047 14.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Ras PF00071.17 EKG22285.1 - 0.0082 15.5 0.1 3.2 7.1 0.0 3.0 3 0 0 3 3 3 1 Ras family AAA_29 PF13555.1 EKG22285.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG22285.1 - 0.011 15.8 0.0 0.07 13.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EKG22285.1 - 0.018 15.3 0.2 0.053 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EKG22285.1 - 0.027 14.7 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EKG22285.1 - 0.03 14.2 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EKG22285.1 - 0.05 13.0 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EKG22285.1 - 0.082 12.6 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EKG22285.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RHD3 PF05879.7 EKG22285.1 - 0.21 9.4 0.3 5.5 4.7 0.0 2.1 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) Myosin_head PF00063.16 EKG22286.1 - 1.8e-235 783.1 6.6 2.7e-235 782.5 4.6 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Pkinase PF00069.20 EKG22286.1 - 1.1e-61 208.3 0.0 1.7e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Myosin_TH1 PF06017.8 EKG22286.1 - 1.3e-47 161.6 0.0 2.6e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Myosin tail Pkinase_Tyr PF07714.12 EKG22286.1 - 2e-41 141.8 0.0 3.3e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 EKG22286.1 - 8e-16 57.1 0.1 1.8e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EKG22286.1 - 2.2e-12 46.3 0.1 8.9e-12 44.4 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EKG22286.1 - 9.1e-10 37.8 0.0 2.4e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Kinase-like PF14531.1 EKG22286.1 - 1.2e-06 27.7 0.0 3.2e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like POLO_box PF00659.13 EKG22286.1 - 2.7e-06 27.2 0.1 0.0039 17.1 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region IQ PF00612.22 EKG22286.1 - 0.0015 17.9 4.1 0.81 9.5 0.7 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EKG22286.1 - 0.0049 17.0 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG22286.1 - 0.022 15.5 0.0 0.099 13.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 EKG22286.1 - 0.023 14.0 0.8 2.3 7.4 0.0 2.6 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain Zeta_toxin PF06414.7 EKG22286.1 - 0.041 12.9 0.0 0.097 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EKG22286.1 - 0.055 13.7 0.0 0.23 11.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EKG22286.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.4 EKG22286.1 - 0.22 10.0 0.0 0.38 9.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain OPA3 PF07047.7 EKG22287.1 - 7.6e-31 106.6 9.1 1.2e-29 102.7 6.3 2.8 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) TSC22 PF01166.13 EKG22287.1 - 0.0016 18.3 1.4 0.004 17.0 1.0 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family Lipoprotein_6 PF01441.14 EKG22287.1 - 0.0025 17.7 1.3 1.2 8.9 0.0 2.1 2 0 0 2 2 2 2 Lipoprotein DUF904 PF06005.7 EKG22287.1 - 0.0057 16.9 1.2 0.0057 16.9 0.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF904) Auxin_repressed PF05564.7 EKG22287.1 - 0.054 14.1 1.0 0.054 14.1 0.7 2.0 2 0 0 2 2 2 0 Dormancy/auxin associated protein IncA PF04156.9 EKG22287.1 - 0.074 12.6 3.3 1.7 8.2 0.2 2.2 2 0 0 2 2 2 0 IncA protein FixQ PF05545.6 EKG22287.1 - 0.13 11.9 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF972 PF06156.8 EKG22287.1 - 0.28 11.5 6.0 0.46 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2681 PF10883.3 EKG22287.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.8 2 1 0 2 2 1 0 Protein of unknown function (DUF2681) DUF4366 PF14283.1 EKG22287.1 - 0.38 10.1 4.2 0.23 10.8 1.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Peptidase_S49_N PF08496.5 EKG22287.1 - 0.86 9.3 5.6 5 6.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DASH_Spc34 PF08657.5 EKG22287.1 - 0.87 9.2 13.6 0.044 13.4 1.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Spc34 ATG16 PF08614.6 EKG22287.1 - 0.9 9.3 12.1 0.23 11.2 1.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Ax_dynein_light PF10211.4 EKG22287.1 - 1.3 8.8 15.4 1.4 8.6 2.0 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain CtIP_N PF10482.4 EKG22287.1 - 1.9 8.2 8.5 1.6 8.5 1.1 2.4 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF4140 PF13600.1 EKG22287.1 - 2.3 8.7 12.7 1.6 9.1 0.8 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ank_2 PF12796.2 EKG22289.1 - 7e-118 385.2 51.0 2.3e-19 69.4 0.4 9.5 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EKG22289.1 - 1.3e-78 255.1 39.8 3.4e-09 36.0 0.1 18.0 19 0 0 19 19 19 14 Ankyrin repeat Ank_4 PF13637.1 EKG22289.1 - 3.1e-70 231.3 24.1 5.8e-10 39.4 0.1 12.8 7 5 5 13 13 13 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG22289.1 - 4e-62 199.9 19.9 9.3e-05 22.3 0.0 17.7 17 1 1 18 18 18 11 Ankyrin repeat Ank_5 PF13857.1 EKG22289.1 - 3.2e-61 201.9 28.6 2.4e-09 37.1 0.2 14.0 3 3 14 17 17 17 14 Ankyrin repeats (many copies) Pkinase PF00069.20 EKG22289.1 - 1.1e-39 136.1 0.0 2.2e-39 135.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EKG22289.1 - 6.3e-28 97.5 0.0 1.1e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EKG22289.1 - 0.0067 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EKG22289.1 - 0.052 12.5 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like L_protein_N PF15518.1 EKG22289.1 - 0.11 11.8 0.0 3.4 6.9 0.0 2.8 3 0 0 3 3 3 0 L protein N-terminus Shigella_OspC PF06128.6 EKG22289.1 - 0.87 9.0 3.1 19 4.6 0.0 3.9 5 1 0 5 5 5 0 Shigella flexneri OspC protein Prenyltransf PF01255.14 EKG22290.1 - 8e-07 28.4 0.0 7.1e-05 22.0 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Sec10 PF07393.6 EKG22291.1 - 4.7e-205 682.9 0.0 1.5e-204 681.2 0.0 1.7 1 1 0 1 1 1 1 Exocyst complex component Sec10 Baculo_PEP_C PF04513.7 EKG22291.1 - 0.34 10.7 6.6 2.9 7.7 0.0 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNARE PF05739.14 EKG22292.1 - 2.4e-09 36.7 1.2 2.4e-09 36.7 0.8 2.8 3 0 0 3 3 3 1 SNARE domain ATP-synt_E PF05680.7 EKG22292.1 - 0.028 14.3 2.4 0.028 14.3 1.6 3.2 1 1 2 3 3 3 0 ATP synthase E chain Usp PF00582.21 EKG22292.1 - 2.1 8.5 8.1 0.21 11.7 0.4 2.4 1 1 1 2 2 2 0 Universal stress protein family Epimerase PF01370.16 EKG22293.1 - 6.2e-56 189.4 0.0 9.1e-56 188.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RRM_1 PF00076.17 EKG22293.1 - 5.1e-30 102.9 0.1 3.3e-11 42.6 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Polysacc_synt_2 PF02719.10 EKG22293.1 - 3e-22 78.8 0.0 2.4e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EKG22293.1 - 1.6e-20 73.1 0.0 2.4e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EKG22293.1 - 2.1e-20 72.6 0.0 2.9e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EKG22293.1 - 8.4e-20 70.7 0.0 6.3e-19 67.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein RRM_6 PF14259.1 EKG22293.1 - 1.7e-18 66.3 0.0 1.9e-05 24.5 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EKG22293.1 - 4.4e-14 52.0 0.0 1.1e-09 38.0 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_10 PF13460.1 EKG22293.1 - 8e-08 32.5 0.0 2.3e-07 31.0 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EKG22293.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 EKG22293.1 - 0.079 12.8 0.1 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase OGG_N PF07934.7 EKG22294.1 - 4e-36 123.5 0.0 8.7e-36 122.4 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EKG22294.1 - 8.1e-17 61.4 0.0 1.5e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EKG22294.1 - 0.00024 20.6 0.0 0.00054 19.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif LANC_like PF05147.8 EKG22295.1 - 6.1e-27 94.1 0.0 1.8e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein Pec_lyase PF09492.5 EKG22295.1 - 0.061 12.4 0.0 0.17 10.9 0.0 1.7 1 1 0 1 1 1 0 Pectic acid lyase Rax2 PF12768.2 EKG22296.1 - 3.8e-90 301.9 14.9 1.1e-79 267.5 0.0 5.0 6 0 0 6 6 6 4 Cortical protein marker for cell polarity Sugar_tr PF00083.19 EKG22301.1 - 7.1e-71 239.1 16.6 9.4e-71 238.7 11.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG22301.1 - 2.3e-18 66.0 22.4 3.4e-18 65.4 15.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EKG22301.1 - 2e-05 23.1 14.5 0.0059 15.0 4.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Carb_kinase PF01256.12 EKG22303.1 - 9e-56 188.8 0.1 1.1e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EKG22303.1 - 0.0046 16.1 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TAFII55_N PF04658.8 EKG22304.1 - 6.4e-50 168.8 0.0 1.4e-49 167.7 0.0 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region Myc_N PF01056.13 EKG22304.1 - 0.0021 17.3 1.5 0.0021 17.3 1.0 3.0 4 0 0 4 4 4 1 Myc amino-terminal region Sigma70_ner PF04546.8 EKG22304.1 - 0.0078 15.8 9.2 0.0078 15.8 6.4 2.4 2 0 0 2 2 2 1 Sigma-70, non-essential region Nucleoplasmin PF03066.10 EKG22304.1 - 0.0087 15.5 1.9 0.0087 15.5 1.3 2.3 2 0 0 2 2 2 1 Nucleoplasmin Sulfatase_C PF14707.1 EKG22304.1 - 0.19 12.0 1.8 0.42 10.8 1.3 1.6 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Rep_4 PF05797.6 EKG22304.1 - 3.4 6.2 6.8 5.6 5.5 4.7 1.3 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Pox_Ag35 PF03286.9 EKG22304.1 - 7.4 6.0 17.2 0.061 12.8 3.3 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Bromo_TP PF07524.8 EKG22305.1 - 7.7e-09 35.1 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated ATP-synt_ab PF00006.20 EKG22307.1 - 6.6e-71 238.2 0.0 9.7e-71 237.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EKG22307.1 - 7e-28 97.3 0.5 1.8e-27 96.0 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EKG22307.1 - 8.4e-16 57.9 2.6 2.2e-15 56.6 1.8 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EKG22307.1 - 0.0095 15.8 1.2 0.096 12.6 0.9 2.5 1 1 0 1 1 1 1 HAS barrel domain Isochorismatase PF00857.15 EKG22309.1 - 6.4e-28 97.8 0.0 1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family PBP PF01161.15 EKG22310.1 - 6.5e-32 110.3 0.3 9e-32 109.9 0.2 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ank_2 PF12796.2 EKG22311.1 - 4.2e-28 97.5 0.3 3.3e-09 36.9 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EKG22311.1 - 2.4e-22 77.5 4.1 4.9e-05 22.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EKG22311.1 - 2.4e-17 62.9 6.6 7.6e-05 23.1 0.0 6.4 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG22311.1 - 3.8e-15 54.4 4.1 0.0082 16.2 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EKG22311.1 - 1.6e-12 47.1 6.2 0.014 15.6 0.2 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Vpu PF00558.14 EKG22311.1 - 0.074 12.6 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Vpu protein Ank_4 PF13637.1 EKG22312.1 - 0.024 15.1 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Reo_sigmaC PF04582.7 EKG22312.1 - 0.035 13.2 0.1 0.072 12.2 0.1 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein FAA_hydrolase PF01557.13 EKG22313.1 - 1.2e-22 80.4 0.0 1.4e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family IncA PF04156.9 EKG22314.1 - 0.0059 16.2 2.1 0.084 12.4 0.2 2.3 1 1 0 2 2 2 1 IncA protein Spc7 PF08317.6 EKG22314.1 - 0.014 14.1 4.4 0.66 8.5 0.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Taxilin PF09728.4 EKG22314.1 - 0.048 12.7 2.4 0.1 11.6 1.6 1.7 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Fib_alpha PF08702.5 EKG22314.1 - 4.1 7.5 6.6 4.7 7.3 0.0 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DEAD PF00270.24 EKG22315.1 - 6.4e-44 149.4 2.9 7.6e-44 149.1 1.4 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EKG22315.1 - 1.3e-27 95.4 0.3 6.1e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG22315.1 - 0.00063 19.6 0.0 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EKG22315.1 - 0.0013 18.3 0.2 0.0041 16.7 0.1 1.8 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.1 EKG22315.1 - 0.0019 17.3 0.0 0.0043 16.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 EKG22315.1 - 0.0042 17.2 0.1 0.013 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EKG22315.1 - 0.0066 16.1 0.2 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain SNF2_N PF00176.18 EKG22315.1 - 0.021 13.5 0.1 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1b PF00579.20 EKG22315.1 - 0.036 13.1 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.9 EKG22315.1 - 0.078 12.7 0.2 0.39 10.4 0.2 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.9 EKG22315.1 - 0.092 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein F-box-like PF12937.2 EKG22316.1 - 4.8e-07 29.3 0.0 6.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EKG22316.1 - 5.5e-05 22.6 0.0 7.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.13 EKG22317.1 - 6.8e-17 61.2 1.9 1.2e-16 60.4 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG22317.1 - 1e-06 28.5 6.8 1.9e-06 27.6 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.10 EKG22318.1 - 9.2e-69 232.2 0.2 1.1e-68 232.0 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.10 EKG22319.1 - 4.1e-18 65.2 0.1 5.4e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein BAH PF01426.13 EKG22321.1 - 4.9e-09 35.9 0.0 8.1e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EKG22321.1 - 0.0024 17.5 2.2 0.0024 17.5 1.5 1.9 2 0 0 2 2 2 1 PHD-finger zf-CSL PF05207.8 EKG22321.1 - 0.059 12.8 0.5 0.91 9.0 0.0 2.3 2 0 0 2 2 2 0 CSL zinc finger PH PF00169.24 EKG22322.1 - 0.00077 19.6 0.0 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EKG22322.1 - 0.0087 16.2 0.5 0.032 14.3 0.0 2.2 3 0 0 3 3 3 1 Pleckstrin homology domain Zip PF02535.17 EKG22323.1 - 7.9e-44 149.9 1.2 3.2e-43 147.9 0.8 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter ResIII PF04851.10 EKG22324.1 - 2.1e-19 70.0 0.0 5.3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EKG22324.1 - 1.6e-18 66.3 0.1 4.7e-18 64.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EKG22324.1 - 1.7e-18 66.6 0.0 4.8e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EKG22324.1 - 0.025 14.7 0.0 0.074 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF457 PF04307.9 EKG22324.1 - 0.14 11.5 0.1 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) F_actin_cap_B PF01115.12 EKG22326.1 - 1.1e-106 355.4 0.0 1.5e-106 354.9 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Fungal_trans PF04082.13 EKG22326.1 - 1.6e-12 46.8 2.0 7.3e-07 28.3 0.0 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EKG22327.1 - 1.1e-17 64.5 0.0 1.3e-17 64.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EKG22327.1 - 3.2e-14 53.1 4.5 5.2e-14 52.5 2.9 1.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EKG22327.1 - 1.8e-08 34.2 0.5 2.2e-08 33.9 0.3 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EKG22327.1 - 0.00021 21.0 0.5 0.023 14.4 0.4 2.6 2 1 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EKG22327.1 - 0.00072 19.6 2.1 0.0032 17.5 1.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding CPSF_A PF03178.10 EKG22329.1 - 4e-96 321.8 0.0 2.4e-95 319.3 0.0 2.3 3 0 0 3 3 3 1 CPSF A subunit region LMBR1 PF04791.11 EKG22330.1 - 5.9e-16 58.1 3.5 5.9e-16 58.1 2.4 2.2 1 1 0 2 2 2 2 LMBR1-like membrane protein Ifi-6-16 PF06140.8 EKG22333.1 - 1.4e-06 27.9 23.4 2.4e-06 27.2 16.2 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family PSI_PSAK PF01241.13 EKG22333.1 - 0.15 12.1 7.0 0.25 11.3 4.9 1.3 1 0 0 1 1 1 0 Photosystem I psaG / psaK DUF1700 PF08006.6 EKG22333.1 - 0.57 9.4 5.2 0.82 8.9 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF605 PF04652.11 EKG22334.1 - 7.9e-95 318.4 16.2 8.9e-95 318.2 11.2 1.0 1 0 0 1 1 1 1 Vta1 like Thioredoxin PF00085.15 EKG22335.1 - 9e-32 108.8 0.0 8.5e-26 89.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EKG22335.1 - 1.7e-10 40.9 0.0 5.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EKG22335.1 - 5.4e-08 33.0 0.3 0.0013 18.8 0.1 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EKG22335.1 - 5.4e-06 26.4 0.1 0.0089 16.1 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EKG22335.1 - 0.00081 19.3 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EKG22335.1 - 0.042 13.3 0.0 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein Glutaredoxin PF00462.19 EKG22335.1 - 0.14 12.2 0.1 16 5.5 0.0 2.7 2 0 0 2 2 2 0 Glutaredoxin Ank_2 PF12796.2 EKG22336.1 - 4.2e-13 49.4 0.1 1.1e-05 25.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EKG22336.1 - 8.1e-13 47.4 0.6 0.0049 16.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EKG22336.1 - 6.1e-11 41.4 0.3 0.043 14.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EKG22336.1 - 1.3e-09 37.9 0.2 0.027 14.7 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EKG22336.1 - 1.5e-08 34.8 0.1 0.0003 21.2 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) p450 PF00067.17 EKG22337.1 - 1.5e-59 201.7 0.0 3.6e-55 187.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Thiolase_N PF00108.18 EKG22338.1 - 1.7e-60 204.2 0.0 2.6e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EKG22338.1 - 1.3e-45 153.7 1.7 2.5e-45 152.8 1.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EKG22338.1 - 0.87 9.2 3.6 5.4 6.7 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 EKG22339.1 - 3.7e-43 147.1 0.0 6.1e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EKG22339.1 - 1.4e-25 89.1 0.0 6.8e-25 86.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EKG22339.1 - 5e-18 64.7 0.0 1.5e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EKG22339.1 - 7.8e-09 35.5 0.3 2e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EKG22339.1 - 2.8e-07 30.2 0.0 7.1e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EKG22339.1 - 4.3e-05 23.4 0.1 8.2e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKG22339.1 - 0.031 14.7 0.1 0.076 13.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Ras PF00071.17 EKG22339.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Ras family Glyco_hydro_16 PF00722.16 EKG22340.1 - 1.4e-07 31.0 0.1 1.4e-07 31.0 0.1 2.4 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 adh_short PF00106.20 EKG22341.1 - 1.5e-16 60.7 4.3 2.6e-14 53.4 0.7 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EKG22341.1 - 2.1e-11 44.0 0.3 1.7e-05 24.6 0.1 2.3 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG22341.1 - 1.1e-08 34.9 0.5 2e-08 34.0 0.3 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EKG22341.1 - 0.0042 16.0 0.0 0.0064 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein VRR_NUC PF08774.6 EKG22342.1 - 8e-18 64.3 0.0 3.3e-17 62.3 0.0 2.0 2 0 0 2 2 2 1 VRR-NUC domain DUF202 PF02656.10 EKG22344.1 - 5.6e-16 58.5 0.1 5.6e-16 58.5 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF202) PcF PF09461.5 EKG22345.1 - 0.012 15.5 0.6 0.012 15.5 0.4 2.3 2 0 0 2 2 2 0 Phytotoxin PcF protein PcF PF09461.5 EKG22346.1 - 0.012 15.4 1.4 0.012 15.4 0.9 2.0 2 1 0 2 2 2 0 Phytotoxin PcF protein HCV_NS5a_1a PF08300.8 EKG22346.1 - 0.27 11.1 4.9 0.22 11.4 2.2 1.7 1 1 1 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain BTB PF00651.26 EKG22349.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Collagen PF01391.13 EKG22352.1 - 9.1e-36 121.2 124.0 9.9e-10 37.8 21.8 4.3 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) GRA6 PF05084.8 EKG22352.1 - 0.033 13.7 0.0 0.033 13.7 0.0 3.8 2 1 2 4 4 4 0 Granule antigen protein (GRA6) DUF2273 PF10031.4 EKG22352.1 - 0.036 13.6 0.4 0.055 13.0 0.2 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF2115 PF09888.4 EKG22355.1 - 0.12 12.5 0.2 0.24 11.5 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Glyco_hydro_3 PF00933.16 EKG22356.1 - 1.3e-89 300.1 0.0 1.9e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EKG22356.1 - 3.7e-57 193.4 0.4 1e-56 191.9 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EKG22356.1 - 4.8e-26 90.4 0.1 9.2e-26 89.5 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PAM2 PF07145.10 EKG22357.1 - 0.0062 15.9 1.2 0.013 14.9 0.8 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Myosin_tail_1 PF01576.14 EKG22357.1 - 0.058 11.1 0.3 0.074 10.7 0.2 1.0 1 0 0 1 1 1 0 Myosin tail DHDPS PF00701.17 EKG22359.1 - 4.2e-34 117.4 0.0 5.6e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Exo_endo_phos PF03372.18 EKG22361.1 - 8e-13 48.8 0.7 1.2e-12 48.3 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dynamin_N PF00350.18 EKG22363.1 - 2.7e-30 105.4 0.0 6.2e-30 104.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EKG22363.1 - 1.1e-18 67.1 0.0 9.1e-16 57.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EKG22363.1 - 0.00025 20.8 0.3 0.0012 18.7 0.0 2.3 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EKG22363.1 - 0.00036 20.4 0.0 0.0043 16.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EKG22363.1 - 0.0017 18.8 0.0 0.0049 17.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein Syntaxin PF00804.20 EKG22363.1 - 0.0047 17.0 0.1 5.3 7.2 0.0 3.2 2 0 0 2 2 2 2 Syntaxin AAA_29 PF13555.1 EKG22363.1 - 0.028 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EKG22363.1 - 0.058 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EKG22363.1 - 0.06 13.6 0.1 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DegS PF05384.6 EKG22363.1 - 0.066 12.4 0.1 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 Sensor protein DegS ChaC PF04752.7 EKG22364.1 - 8.5e-35 120.3 0.0 1.3e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein Complex1_49kDa PF00346.14 EKG22365.1 - 4.8e-134 445.5 0.0 6.1e-134 445.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EKG22365.1 - 0.081 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.21 EKG22366.1 - 4.5e-28 97.6 0.0 8.8e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EKG22366.1 - 1.2e-13 49.9 0.0 2.3e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ATP-synt PF00231.14 EKG22368.1 - 2.7e-69 233.7 2.1 3.2e-69 233.5 1.4 1.0 1 0 0 1 1 1 1 ATP synthase DUF108 PF01958.13 EKG22368.1 - 0.016 15.3 0.4 0.04 14.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF108 Topoisom_I_N PF02919.10 EKG22369.1 - 7.4e-100 332.6 3.4 7.4e-100 332.6 2.4 3.5 4 1 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EKG22369.1 - 1.2e-86 289.6 7.0 1.2e-86 289.6 4.8 2.2 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EKG22369.1 - 4.9e-32 109.4 0.4 1.8e-31 107.5 0.3 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain FliC PF12445.3 EKG22369.1 - 0.042 13.9 3.2 0.66 10.0 0.1 2.6 2 0 0 2 2 2 0 Flagellin protein RolB_RolC PF02027.12 EKG22369.1 - 0.083 12.0 0.0 0.24 10.5 0.0 1.7 1 0 0 1 1 1 0 RolB/RolC glucosidase family LEA_3 PF03242.8 EKG22369.1 - 0.87 9.8 5.2 0.58 10.4 0.7 2.7 2 0 0 2 2 2 0 Late embryogenesis abundant protein Epimerase PF01370.16 EKG22370.1 - 7.7e-11 41.8 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EKG22370.1 - 1.3e-08 34.0 0.0 1.8e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EKG22370.1 - 0.00043 20.3 0.0 0.00075 19.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Abhydrolase_3 PF07859.8 EKG22371.1 - 1.4e-47 161.9 0.2 1.8e-47 161.6 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EKG22371.1 - 0.0098 14.6 0.0 0.019 13.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family MFS_1 PF07690.11 EKG22372.1 - 6.7e-05 21.7 2.4 0.00037 19.3 0.1 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG22372.1 - 0.13 10.7 6.1 0.29 9.6 2.2 2.1 1 1 1 2 2 2 0 Sugar (and other) transporter TRI12 PF06609.8 EKG22372.1 - 0.18 9.9 7.1 0.18 9.9 0.4 2.4 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Asn_synthase PF00733.16 EKG22374.1 - 1.8e-57 194.7 0.0 2.3e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EKG22374.1 - 1.1e-33 115.6 0.0 1.9e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EKG22374.1 - 8.8e-31 106.6 0.0 1.6e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EKG22374.1 - 0.0012 18.0 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.11 EKG22374.1 - 0.025 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Sugar_tr PF00083.19 EKG22375.1 - 4.3e-94 315.6 13.6 5e-94 315.4 9.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG22375.1 - 9.4e-23 80.4 20.6 1.1e-22 80.2 14.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SHR3_chaperone PF08229.6 EKG22375.1 - 0.14 11.0 1.5 2.7 6.8 0.0 2.3 1 1 1 2 2 2 0 ER membrane protein SH3 PUCC PF03209.10 EKG22375.1 - 0.41 9.3 12.1 0.026 13.2 4.5 1.7 2 0 0 2 2 2 0 PUCC protein YrhC PF14143.1 EKG22375.1 - 2.7 7.9 5.2 2.1 8.3 1.3 2.5 2 0 0 2 2 2 0 YrhC-like protein CHAT PF12770.2 EKG22377.1 - 6.5e-32 110.8 0.0 1.2e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EKG22377.1 - 1.9e-08 34.0 13.0 0.0045 16.8 0.2 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EKG22377.1 - 1.3e-06 27.9 8.2 0.0063 16.1 0.1 5.6 4 1 2 6 6 6 2 TPR repeat ATP-synt_ab_N PF02874.18 EKG22377.1 - 0.035 14.3 0.0 0.085 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain TPR_14 PF13428.1 EKG22377.1 - 0.097 13.3 24.0 14 6.6 0.1 8.0 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_10 PF13374.1 EKG22377.1 - 9.7 6.2 16.1 2.7 8.0 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat CpXC PF14353.1 EKG22378.1 - 0.012 15.5 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 CpXC protein Peptidase_C14 PF00656.17 EKG22379.1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Caspase domain SnoaL_4 PF13577.1 EKG22380.1 - 0.00014 21.7 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain HET PF06985.6 EKG22381.1 - 1.9e-19 70.2 0.0 3.4e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Vps8 PF12816.2 EKG22382.1 - 3.8e-68 228.5 0.0 8e-68 227.5 0.0 1.6 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EKG22382.1 - 4.6e-08 32.7 0.0 0.34 10.5 0.0 3.7 3 0 0 3 3 3 3 Region in Clathrin and VPS CDK5_activator PF03261.10 EKG22382.1 - 0.071 12.4 5.9 0.12 11.6 4.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein tRNA-synt_2c PF01411.14 EKG22385.1 - 3.9e-215 715.3 0.2 3.9e-215 715.3 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EKG22385.1 - 5.8e-17 61.2 0.1 1.9e-16 59.6 0.1 2.0 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EKG22385.1 - 2.5e-07 30.3 0.8 7.8e-07 28.7 0.6 1.9 1 0 0 1 1 1 1 DHHA1 domain SPOUT_MTase PF02590.12 EKG22385.1 - 0.48 10.1 4.4 8.4 6.0 1.0 2.6 2 1 0 2 2 2 0 Predicted SPOUT methyltransferase ABC2_membrane PF01061.19 EKG22387.1 - 1.2e-82 276.2 60.8 7.1e-44 149.4 15.5 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EKG22387.1 - 4.1e-41 140.4 0.0 2.3e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EKG22387.1 - 9.9e-36 121.5 5.1 8.8e-33 112.0 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EKG22387.1 - 3.6e-12 45.9 34.1 1.1e-10 41.0 2.3 3.3 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EKG22387.1 - 8.8e-12 44.8 0.0 4.9e-05 22.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EKG22387.1 - 6.5e-07 28.6 0.0 5.6e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EKG22387.1 - 1.4e-06 28.3 3.4 2.6e-05 24.3 0.1 2.8 3 0 0 3 3 2 1 AAA ATPase domain UPF0079 PF02367.12 EKG22387.1 - 3.2e-05 23.5 0.6 0.039 13.5 0.0 2.7 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EKG22387.1 - 6.9e-05 22.9 0.0 1.1 9.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_trans_N PF14510.1 EKG22387.1 - 0.00013 21.9 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 EKG22387.1 - 0.00017 21.0 0.9 0.043 13.2 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EKG22387.1 - 0.00072 19.0 0.3 0.075 12.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EKG22387.1 - 0.0015 18.2 0.6 0.056 13.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EKG22387.1 - 0.0024 18.0 1.6 0.093 12.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EKG22387.1 - 0.0034 17.0 1.2 0.45 10.2 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EKG22387.1 - 0.0063 16.3 0.3 0.57 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EKG22387.1 - 0.0081 16.4 0.4 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EKG22387.1 - 0.01 15.7 0.2 1.3 9.0 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EKG22387.1 - 0.013 15.4 0.6 0.13 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EKG22387.1 - 0.016 15.1 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 EKG22387.1 - 0.019 15.1 0.2 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EKG22387.1 - 0.021 15.6 0.0 0.52 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EKG22387.1 - 0.037 13.2 0.0 0.55 9.4 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EKG22387.1 - 0.069 12.0 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EKG22387.1 - 0.13 11.3 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 EKG22387.1 - 0.13 11.9 0.2 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TMEM173 PF15009.1 EKG22387.1 - 0.14 10.9 2.0 0.94 8.2 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 173 PduV-EutP PF10662.4 EKG22387.1 - 0.14 11.6 2.4 2 7.9 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EKG22387.1 - 0.14 10.9 0.5 4.5 6.0 0.0 2.7 3 0 0 3 3 2 0 NB-ARC domain RNA_helicase PF00910.17 EKG22387.1 - 0.14 12.3 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 EKG22387.1 - 0.15 11.4 0.6 32 3.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.1 EKG22387.1 - 0.16 11.5 0.3 18 4.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EKG22387.1 - 0.18 11.3 0.9 2 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EKG22387.1 - 0.2 12.1 0.0 20 5.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EKG22387.1 - 0.21 11.8 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EKG22387.1 - 0.22 11.2 0.4 9 5.9 0.1 2.9 3 0 0 3 3 3 0 NTPase Septin PF00735.13 EKG22387.1 - 0.31 10.0 0.3 3.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Septin Fungal_trans PF04082.13 EKG22388.1 - 2.1e-16 59.5 5.8 3.7e-16 58.7 4.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TrkH PF02386.11 EKG22389.1 - 4.3e-43 147.2 0.1 1.1e-21 76.8 0.1 2.0 2 0 0 2 2 2 2 Cation transport protein Na_H_Exchanger PF00999.16 EKG22390.1 - 1.5e-32 112.5 14.3 2.3e-32 112.0 9.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EKG22390.1 - 0.015 15.2 1.1 0.049 13.5 0.1 2.4 2 0 0 2 2 2 0 YrhC-like protein HpcH_HpaI PF03328.9 EKG22391.1 - 1.7e-20 72.9 2.2 2.7e-20 72.2 1.5 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family NUDIX PF00293.23 EKG22391.1 - 1.6e-12 47.1 0.0 3.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain PEP_mutase PF13714.1 EKG22391.1 - 0.025 13.7 5.2 0.3 10.2 0.0 3.0 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase SnoaL PF07366.7 EKG22392.1 - 1.7e-08 34.0 0.0 3.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EKG22392.1 - 3.1e-05 24.3 0.0 6.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like domain Fungal_trans PF04082.13 EKG22393.1 - 1.1e-29 103.0 0.0 1.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Not3 PF04065.10 EKG22393.1 - 0.13 11.5 0.1 0.26 10.5 0.1 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DUF2406 PF10295.4 EKG22394.1 - 3.2e-21 75.6 0.1 1.2e-20 73.7 0.1 2.1 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 EKG22395.1 - 3.1e-16 59.0 8.3 4.4e-16 58.5 5.8 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.18 EKG22396.1 - 1.8e-61 207.5 0.2 2.6e-61 207.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EKG22396.1 - 1.8e-14 53.3 0.0 3.9e-14 52.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG22396.1 - 3.6e-10 39.9 0.0 8.4e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Calreticulin PF00262.13 EKG22397.1 - 2e-166 553.1 20.9 2e-166 553.1 14.5 1.5 2 0 0 2 2 2 1 Calreticulin family Pkinase PF00069.20 EKG22398.1 - 2.3e-10 40.0 0.0 2.7e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ERO1 PF04137.10 EKG22401.1 - 1e-136 455.6 0.0 1.4e-136 455.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TAP_C PF03943.8 EKG22402.1 - 8.3e-12 44.3 0.0 1.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EKG22402.1 - 1.5e-05 24.4 6.7 0.001 18.6 1.0 2.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) NTF2 PF02136.15 EKG22402.1 - 0.0067 16.7 0.0 0.019 15.3 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.1 EKG22402.1 - 0.029 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_8 PF13855.1 EKG22402.1 - 0.042 13.6 0.6 0.097 12.4 0.4 1.7 1 0 0 1 1 1 0 Leucine rich repeat LRR_7 PF13504.1 EKG22402.1 - 0.043 13.9 0.2 1.1 9.7 0.1 3.1 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 EKG22402.1 - 0.066 13.2 0.1 7 7.1 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat Chromo PF00385.19 EKG22404.1 - 1.6e-08 34.1 1.6 3.1e-08 33.1 1.1 1.6 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EKG22404.1 - 0.078 12.6 1.4 0.11 12.2 0.9 1.4 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain Allantoicase PF03561.10 EKG22407.1 - 6.1e-98 324.4 0.1 1.8e-52 176.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 EKG22407.1 - 0.037 13.8 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 F5/8 type C domain CorA PF01544.13 EKG22408.1 - 4.4e-44 150.6 0.5 6.8e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Frag1 PF10277.4 EKG22409.1 - 7e-24 84.5 17.6 8.8e-24 84.1 12.2 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family CRCB PF02537.10 EKG22409.1 - 0.015 15.1 5.4 0.027 14.3 2.1 2.2 2 0 0 2 2 2 0 CrcB-like protein DUF2678 PF10856.3 EKG22409.1 - 0.15 11.7 4.6 0.052 13.2 1.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) DUF754 PF05449.6 EKG22409.1 - 3.5 7.7 13.3 0.52 10.3 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF754) MARVEL PF01284.18 EKG22409.1 - 6.2 6.6 20.4 1.7 8.4 5.6 2.4 1 1 0 2 2 2 0 Membrane-associating domain DSBA PF01323.15 EKG22410.1 - 2.1e-40 138.3 0.0 2.4e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EKG22410.1 - 0.00042 20.3 0.0 0.0014 18.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.1 EKG22410.1 - 0.0078 16.0 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain DUF3611 PF12263.3 EKG22411.1 - 0.086 12.2 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) CcmD PF04995.9 EKG22411.1 - 0.14 11.9 2.7 0.32 10.7 1.2 1.9 1 1 1 2 2 2 0 Heme exporter protein D (CcmD) DOPA_dioxygen PF08883.6 EKG22412.1 - 6.7e-31 106.4 0.0 8.3e-31 106.1 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family AP_endonuc_2 PF01261.19 EKG22415.1 - 1.3e-26 93.2 0.1 2.1e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel RrnaAD PF00398.15 EKG22416.1 - 3.2e-59 200.1 0.0 4.3e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EKG22416.1 - 1.3e-10 41.3 0.0 3.1e-10 40.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG22416.1 - 1.3e-06 28.9 0.0 3.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG22416.1 - 3.7e-06 26.5 0.0 2.2e-05 24.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EKG22416.1 - 1.9e-05 24.1 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EKG22416.1 - 4.8e-05 23.7 0.0 0.00014 22.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EKG22416.1 - 0.0001 22.0 0.2 0.0004 20.0 0.0 2.0 2 0 0 2 2 2 1 Met-10+ like-protein PCMT PF01135.14 EKG22416.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EKG22416.1 - 0.0011 18.2 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EKG22416.1 - 0.0011 19.3 0.0 0.0034 17.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EKG22416.1 - 0.0017 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EKG22416.1 - 0.0019 17.9 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EKG22416.1 - 0.054 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EKG22416.1 - 0.07 12.1 0.8 0.098 11.6 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase UPF0020 PF01170.13 EKG22416.1 - 0.071 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EKG22416.1 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF4358 PF14270.1 EKG22416.1 - 3.3 7.6 5.7 0.5 10.2 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Cyclase PF04199.8 EKG22417.1 - 2.9e-13 49.8 0.1 4.8e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Putative cyclase AAA_23 PF13476.1 EKG22418.1 - 7.6 6.7 7.9 16 5.7 5.5 1.5 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.2 EKG22421.1 - 0.009 16.3 0.0 0.053 13.8 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EKG22421.1 - 0.013 15.7 0.1 14 6.2 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeat ADH_N PF08240.7 EKG22422.1 - 1.5e-10 40.7 0.0 2.8e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG22422.1 - 2.4e-09 36.8 0.9 5.2e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EKG22422.1 - 0.069 13.1 1.2 0.13 12.2 0.8 1.5 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EKG22423.1 - 0.00057 19.8 0.0 0.51 10.2 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase HsbA PF12296.3 EKG22424.1 - 0.0057 16.4 3.1 0.01 15.6 0.6 2.0 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DUF1289 PF06945.8 EKG22425.1 - 0.17 11.3 0.2 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) adh_short PF00106.20 EKG22426.1 - 1e-21 77.5 1.9 2.8e-21 76.1 1.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG22426.1 - 9.3e-11 41.9 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EKG22426.1 - 9e-05 22.5 0.1 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EKG22426.1 - 0.001 18.7 2.8 0.021 14.4 2.0 2.3 1 1 0 1 1 1 1 KR domain Lipase_GDSL_2 PF13472.1 EKG22427.1 - 1.9e-17 63.9 0.2 5.8e-17 62.3 0.1 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EKG22427.1 - 1.8e-06 27.9 0.0 6.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase GatB_N PF02934.10 EKG22428.1 - 1.1e-31 109.7 0.0 1.5e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EKG22428.1 - 2e-21 76.2 0.1 2.9e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 GatB domain adh_short PF00106.20 EKG22429.1 - 4.5e-18 65.7 7.7 8.9e-15 54.9 2.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EKG22429.1 - 3.3e-11 43.1 3.3 1.1e-09 38.2 0.2 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EKG22429.1 - 1.4e-10 41.3 0.3 0.00039 20.2 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EKG22429.1 - 0.04 12.8 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SepZ PF06066.6 EKG22429.1 - 1.2 9.2 7.0 2.6 8.0 0.1 3.0 2 1 1 3 3 3 0 SepZ CBM_1 PF00734.13 EKG22430.1 - 3.6e-13 48.9 11.3 3.6e-13 48.9 7.8 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EKG22430.1 - 0.25 11.4 2.5 0.46 10.5 1.8 1.4 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_6 PF01341.12 EKG22431.1 - 1.2e-16 61.0 0.0 1.8e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EKG22431.1 - 2.6e-12 46.1 6.9 2.6e-12 46.1 4.8 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain ATP_bind_1 PF03029.12 EKG22432.1 - 3.6e-77 259.0 0.1 5.3e-77 258.5 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EKG22432.1 - 6.4e-06 26.9 0.0 2e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EKG22432.1 - 0.0002 21.2 0.0 0.00083 19.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EKG22432.1 - 0.0015 18.0 0.2 0.0038 16.7 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EKG22432.1 - 0.0069 16.5 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EKG22432.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EKG22432.1 - 0.011 15.9 0.0 0.03 14.4 0.0 1.8 2 0 0 2 2 1 0 RNA helicase MMR_HSR1 PF01926.18 EKG22432.1 - 0.011 15.6 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.24 EKG22432.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EKG22432.1 - 0.016 15.4 0.0 0.11 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EKG22432.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain GTP_EFTU PF00009.22 EKG22432.1 - 0.02 14.3 0.2 5.7 6.3 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 EKG22432.1 - 0.021 14.5 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 EKG22432.1 - 0.033 13.6 0.1 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EKG22432.1 - 0.036 14.3 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 EKG22432.1 - 0.037 13.7 0.0 0.089 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EKG22432.1 - 0.046 12.4 0.0 0.099 11.4 0.0 1.4 2 0 0 2 2 2 0 ArgK protein AAA_24 PF13479.1 EKG22432.1 - 0.047 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EKG22432.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EKG22432.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EKG22432.1 - 0.059 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 EKG22432.1 - 0.088 12.7 0.0 0.21 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EKG22432.1 - 0.13 11.3 0.0 8.5 5.4 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family KaiC PF06745.8 EKG22432.1 - 0.14 11.2 0.0 0.32 10.0 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.1 EKG22432.1 - 0.16 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EKG22432.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 EKG22432.1 - 0.18 10.9 0.0 0.34 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 S-AdoMet_synt_C PF02773.11 EKG22433.1 - 1.4e-75 251.5 0.1 2.8e-75 250.6 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EKG22433.1 - 2.6e-48 162.9 0.0 4.6e-48 162.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EKG22433.1 - 9.8e-43 144.4 0.0 2.6e-42 143.1 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Sas10_Utp3 PF04000.10 EKG22434.1 - 1.5e-15 57.1 0.5 2.6e-15 56.3 0.4 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Daxx PF03344.10 EKG22434.1 - 0.0084 14.6 11.8 0.012 14.1 8.2 1.2 1 0 0 1 1 1 1 Daxx Family BUD22 PF09073.5 EKG22434.1 - 1.2 8.1 27.5 0.011 14.9 10.9 2.2 2 0 0 2 2 2 0 BUD22 Pro-rich PF15240.1 EKG22434.1 - 1.2 9.1 5.5 8 6.5 4.0 2.0 1 1 1 2 2 2 0 Proline-rich TFIIA PF03153.8 EKG22434.1 - 1.8 8.3 12.8 3.3 7.5 8.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 EKG22434.1 - 3.6 6.7 13.0 6.9 5.8 9.0 1.5 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.10 EKG22434.1 - 4.9 5.6 5.0 6.5 5.2 3.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein F-box-like PF12937.2 EKG22435.1 - 0.00063 19.4 0.1 0.0021 17.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like NIF PF03031.13 EKG22436.1 - 2.8e-27 95.3 0.0 6.3e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EKG22436.1 - 3.6e-11 43.0 0.1 2e-10 40.6 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EKG22436.1 - 8.2e-10 38.4 0.5 1.6e-09 37.4 0.4 1.6 1 0 0 1 1 1 1 twin BRCT domain tRNA-synt_2 PF00152.15 EKG22437.1 - 1.8e-70 237.3 0.4 3.1e-70 236.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EKG22437.1 - 8.2e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1524 PF07510.6 EKG22438.1 - 6.1e-13 48.8 0.0 7.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EKG22438.1 - 0.026 14.1 0.7 0.14 11.7 0.5 2.2 1 1 0 1 1 1 0 HNH endonuclease Fungal_trans PF04082.13 EKG22440.1 - 1.2e-25 89.8 0.3 1.8e-25 89.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EKG22441.1 - 2.9e-23 82.6 2.2 9.8e-23 80.8 1.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG22441.1 - 1e-10 41.5 0.1 1.4e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG22441.1 - 5.2e-08 32.6 0.0 5.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EKG22441.1 - 0.0042 17.1 0.5 0.01 15.8 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EKG22441.1 - 0.059 12.2 0.0 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EKG22441.1 - 0.064 12.1 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Herpes_ICP4_C PF03585.9 EKG22441.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein C-terminal region Lactonase PF10282.4 EKG22442.1 - 1.1e-08 34.5 3.7 1.4e-07 30.9 2.5 2.6 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 EKG22442.1 - 1.9e-05 23.1 0.7 0.00012 20.4 0.2 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Reg_prop PF07494.6 EKG22442.1 - 0.016 15.1 0.0 18 5.7 0.0 3.3 2 0 0 2 2 2 0 Two component regulator propeller XRCC1_N PF01834.11 EKG22442.1 - 0.023 14.1 0.4 0.61 9.5 0.1 2.4 2 0 0 2 2 2 0 XRCC1 N terminal domain TRI12 PF06609.8 EKG22444.1 - 5.1e-52 176.8 21.2 6.8e-52 176.4 14.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EKG22444.1 - 2.2e-29 102.3 43.8 8.9e-27 93.7 28.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EKG22445.1 - 1.3e-09 37.1 0.1 1.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 EKG22447.1 - 1.5e-51 175.1 8.4 1.5e-51 175.1 5.9 1.3 2 0 0 2 2 2 1 RTA1 like protein SCIMP PF15050.1 EKG22447.1 - 0.2 11.5 0.3 0.45 10.4 0.2 1.6 1 0 0 1 1 1 0 SCIMP protein Crystall PF00030.14 EKG22454.1 - 0.018 14.9 0.4 0.027 14.3 0.3 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin p450 PF00067.17 EKG22458.1 - 9.5e-57 192.5 0.0 1.2e-56 192.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EMP70 PF02990.11 EKG22459.1 - 0.15 10.4 0.2 0.19 10.1 0.1 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF3237 PF11578.3 EKG22460.1 - 1.9e-20 72.6 0.1 2.2e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) ADH_zinc_N PF00107.21 EKG22461.1 - 1.2e-11 44.3 0.1 2.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EKG22461.1 - 1.5e-07 31.1 0.4 2.4e-06 27.2 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EKG22462.1 - 1.2e-68 231.8 0.0 1.5e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EKG22462.1 - 2.3e-24 86.0 0.0 4.3e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EKG22462.1 - 2.2e-19 69.8 0.0 4.6e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EKG22462.1 - 3.1e-15 56.6 0.0 8.8e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EKG22462.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain NAD_binding_6 PF08030.7 EKG22462.1 - 0.18 11.7 0.0 20 5.0 0.0 2.5 1 1 0 2 2 2 0 Ferric reductase NAD binding domain adh_short PF00106.20 EKG22463.1 - 3.5e-18 66.0 0.0 6.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG22463.1 - 4.3e-08 33.0 0.0 6.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EKG22463.1 - 0.00033 20.4 0.0 0.00049 19.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EKG22463.1 - 0.00056 18.8 0.0 0.00075 18.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EKG22463.1 - 0.037 13.4 0.0 0.054 12.9 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EKG22463.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HET PF06985.6 EKG22465.1 - 1.2e-35 122.6 0.8 2.6e-35 121.5 0.6 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA PF00004.24 EKG22466.1 - 2.9e-16 59.8 0.0 5.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EKG22466.1 - 0.00021 21.6 0.0 0.0022 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKG22466.1 - 0.00093 19.3 0.0 0.0035 17.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG22466.1 - 0.0028 18.4 0.1 0.015 16.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG22466.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EKG22466.1 - 0.0085 15.8 0.0 0.051 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zot PF05707.7 EKG22466.1 - 0.025 14.0 0.1 0.59 9.5 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EKG22466.1 - 0.03 14.0 0.0 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain TIP49 PF06068.8 EKG22466.1 - 0.034 12.8 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EKG22466.1 - 0.035 13.5 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.7 EKG22466.1 - 0.054 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EKG22466.1 - 0.087 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NTPase KaiC PF06745.8 EKG22466.1 - 0.1 11.7 0.1 0.41 9.7 0.1 1.9 2 0 0 2 2 2 0 KaiC Glyco_hydro_43 PF04616.9 EKG22467.1 - 1.4e-28 99.7 0.5 3.2e-18 65.8 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Amidohydro_1 PF01979.15 EKG22468.1 - 4.3e-18 66.0 0.0 1.7e-17 64.1 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EKG22468.1 - 3.3e-13 50.2 5.1 5.3e-13 49.6 3.5 1.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EKG22468.1 - 1.4e-10 40.8 0.1 4e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EKG22468.1 - 1.4e-09 37.6 0.0 0.0016 17.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Fungal_trans PF04082.13 EKG22470.1 - 4.9e-12 45.2 0.0 7.8e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG22470.1 - 6.1e-10 38.8 7.7 1.1e-09 38.0 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 EKG22470.1 - 0.036 13.8 0.3 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 Basic region leucine zipper p450 PF00067.17 EKG22472.1 - 3.7e-52 177.3 0.0 4.4e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Iso_dh PF00180.15 EKG22473.1 - 3.2e-51 174.3 0.0 3.9e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TRP PF06011.7 EKG22474.1 - 5.8e-116 387.6 26.7 7e-116 387.3 18.5 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EKG22474.1 - 8e-38 129.6 0.1 1.3e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 ML-like domain WSC PF01822.14 EKG22475.1 - 1.2e-119 390.4 127.2 2.3e-18 65.9 7.5 8.3 7 1 1 8 8 8 7 WSC domain PQQ_3 PF13570.1 EKG22475.1 - 0.003 17.7 9.6 1.5 9.1 0.1 6.8 6 0 0 6 6 6 2 PQQ-like domain DHquinase_II PF01220.14 EKG22475.1 - 0.017 14.4 0.7 0.044 13.1 0.5 1.6 1 0 0 1 1 1 0 Dehydroquinase class II Reprolysin_3 PF13582.1 EKG22477.1 - 0.45 11.0 2.4 0.42 11.1 0.7 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Abhydrolase_6 PF12697.2 EKG22479.1 - 2.6e-27 96.1 5.1 3.5e-27 95.7 3.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG22479.1 - 5.1e-13 49.1 0.9 2.5e-12 46.8 0.6 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG22479.1 - 2e-10 40.6 0.8 8.7e-10 38.5 0.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EKG22479.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase SKG6 PF08693.5 EKG22480.1 - 4.3e-07 29.1 1.2 9.4e-07 28.0 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1180 PF06679.7 EKG22480.1 - 0.00015 21.6 3.3 0.00015 21.6 2.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) Rax2 PF12768.2 EKG22480.1 - 0.013 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Rifin_STEVOR PF02009.11 EKG22480.1 - 0.087 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family DUF2681 PF10883.3 EKG22480.1 - 0.2 11.9 0.2 0.33 11.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF605 PF04652.11 EKG22481.1 - 1.1 8.5 17.4 1.4 8.2 12.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF883 PF05957.8 EKG22482.1 - 0.12 12.7 1.4 0.23 11.9 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Glt_symporter PF03616.9 EKG22482.1 - 0.2 10.0 1.0 8.1 4.8 0.1 2.0 2 0 0 2 2 2 0 Sodium/glutamate symporter V_ATPase_I PF01496.14 EKG22482.1 - 0.25 9.1 1.1 0.34 8.7 0.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pneumo_att_G PF05539.6 EKG22482.1 - 0.42 9.9 11.0 0.56 9.5 7.6 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF904 PF06005.7 EKG22482.1 - 0.51 10.6 5.4 0.91 9.8 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) XhlA PF10779.4 EKG22482.1 - 2.1 8.3 7.1 4 7.4 4.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA Mif2_N PF15624.1 EKG22482.1 - 3.2 8.3 11.5 5.4 7.6 8.0 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal ADH_N PF08240.7 EKG22484.1 - 6.9e-34 115.8 0.8 1.4e-33 114.8 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EKG22484.1 - 5e-15 55.1 0.0 8.7e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EKG22484.1 - 0.00011 21.3 0.1 0.00019 20.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.1 EKG22484.1 - 0.009 16.9 0.0 0.023 15.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.1 EKG22484.1 - 0.042 13.8 0.2 0.12 12.4 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 EKG22484.1 - 0.061 13.2 0.2 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EKG22484.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 KR domain NADH_4Fe-4S PF10589.4 EKG22484.1 - 6.5 5.9 6.1 1.2 8.3 0.5 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Sugar_tr PF00083.19 EKG22485.1 - 9.9e-131 436.4 27.5 1.6e-130 435.7 19.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG22485.1 - 4.4e-34 117.7 60.5 5.5e-29 100.9 20.9 2.9 3 1 1 4 4 4 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EKG22485.1 - 1.2e-24 86.5 0.0 2.4e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.8 EKG22485.1 - 2.7e-07 29.1 1.1 2.7e-07 29.1 0.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EKG22485.1 - 0.026 13.2 9.4 0.022 13.5 1.8 3.0 2 1 1 3 3 3 0 BT1 family GNAT_acetyltr_2 PF13718.1 EKG22487.1 - 1.2e-79 266.1 0.0 2.1e-79 265.4 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EKG22487.1 - 9.2e-66 220.8 0.0 3.4e-65 218.9 0.0 2.0 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 EKG22487.1 - 2.4e-40 136.0 0.0 6.5e-40 134.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EKG22487.1 - 1.8e-33 114.6 0.1 5.6e-33 113.0 0.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EKG22487.1 - 0.002 18.2 0.0 0.0067 16.5 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_transf_90 PF05686.7 EKG22488.1 - 4e-17 61.9 0.0 5.7e-12 45.0 0.0 3.7 3 2 0 3 3 3 3 Glycosyl transferase family 90 Aldo_ket_red PF00248.16 EKG22489.1 - 4.4e-56 189.7 0.0 5e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL PF00657.17 EKG22493.1 - 5.6e-22 78.7 0.0 6.8e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EKG22493.1 - 8.1e-08 32.5 0.2 1.6e-07 31.5 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ADP_ribosyl_GH PF03747.9 EKG22494.1 - 5.7e-34 118.2 0.1 8.2e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase FA_desaturase PF00487.19 EKG22495.1 - 0.066 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF3433 PF11915.3 EKG22496.1 - 2.1e-17 63.0 1.9 2.1e-17 63.0 1.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) COX2_TM PF02790.10 EKG22496.1 - 0.079 12.9 3.1 0.13 12.2 0.7 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Sugar_tr PF00083.19 EKG22497.1 - 9.8e-11 40.8 1.4 1.2e-10 40.5 0.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Imm40 PF15582.1 EKG22497.1 - 0.02 13.5 0.0 0.025 13.2 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 40 ADH_zinc_N PF00107.21 EKG22499.1 - 0.076 12.5 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Cellulase PF00150.13 EKG22500.1 - 0.0033 16.6 0.3 0.0037 16.5 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glt_symporter PF03616.9 EKG22501.1 - 0.045 12.2 0.0 0.059 11.8 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Ribosomal_L29 PF00831.18 EKG22501.1 - 0.051 13.2 3.1 0.11 12.2 2.2 1.5 1 0 0 1 1 1 0 Ribosomal L29 protein FlxA PF14282.1 EKG22501.1 - 0.11 12.5 0.1 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 FlxA-like protein AAA PF00004.24 EKG22503.1 - 6.3e-15 55.5 0.0 1.6e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EKG22503.1 - 4.5e-13 49.1 0.0 3.6e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase III, delta subunit AAA_22 PF13401.1 EKG22503.1 - 3.9e-09 36.7 0.0 2.1e-06 27.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain Rep_fac_C PF08542.6 EKG22503.1 - 6.8e-09 35.5 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 EKG22503.1 - 4.8e-06 25.7 0.0 1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EKG22503.1 - 7.2e-06 25.6 0.1 0.00011 21.9 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Rad17 PF03215.10 EKG22503.1 - 1e-05 24.4 0.0 1.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 EKG22503.1 - 1.4e-05 24.8 0.0 1.8e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EKG22503.1 - 3.2e-05 24.0 0.1 0.00068 19.6 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EKG22503.1 - 9.3e-05 21.6 0.0 0.0054 15.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EKG22503.1 - 0.0011 18.8 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EKG22503.1 - 0.0016 17.3 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 EKG22503.1 - 0.0023 16.9 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EKG22503.1 - 0.0028 17.0 0.1 0.015 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EKG22503.1 - 0.0029 17.2 0.2 0.0082 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG22503.1 - 0.0045 17.7 0.1 0.022 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EKG22503.1 - 0.0078 15.9 0.1 0.049 13.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EKG22503.1 - 0.014 14.8 0.1 0.29 10.5 0.0 2.6 2 1 1 3 3 3 0 AAA-like domain AAA_33 PF13671.1 EKG22503.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EKG22503.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EKG22503.1 - 0.028 13.9 0.1 0.096 12.1 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.24 EKG22503.1 - 0.029 13.8 0.0 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_30 PF13604.1 EKG22503.1 - 0.033 13.7 0.0 0.24 10.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EKG22503.1 - 0.036 13.6 0.0 1.1 8.8 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EKG22503.1 - 0.038 14.2 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EKG22503.1 - 0.059 12.1 0.0 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain PhoH PF02562.11 EKG22503.1 - 0.085 12.0 0.1 4.4 6.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 EKG22503.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.10 EKG22503.1 - 0.14 11.9 0.0 0.42 10.4 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit CENP-B_dimeris PF09026.5 EKG22504.1 - 1.6 9.0 11.1 0.39 10.9 3.9 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3844 PF12955.2 EKG22505.1 - 5e-36 122.9 2.4 7.5e-36 122.3 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Sec66 PF09802.4 EKG22506.1 - 1.7e-53 180.8 0.0 2.3e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 NPL4 PF05021.10 EKG22507.1 - 6.2e-127 422.9 0.0 7.7e-127 422.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EKG22507.1 - 1.4e-72 242.1 0.1 2.1e-72 241.5 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EKG22507.1 - 0.086 13.1 0.0 0.22 11.8 0.0 1.7 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 His_Phos_2 PF00328.17 EKG22508.1 - 1.3e-23 83.9 0.0 1.6e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) adh_short PF00106.20 EKG22509.1 - 5e-29 101.3 8.8 5e-29 101.3 6.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EKG22509.1 - 1.2e-27 97.3 1.6 1.4e-27 96.9 1.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EKG22509.1 - 3.4e-07 30.1 5.4 3.9e-07 29.9 3.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG22509.1 - 5.6e-05 22.6 0.0 8.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EKG22509.1 - 0.0028 17.5 0.7 0.0058 16.4 0.5 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.1 EKG22509.1 - 1.8 8.5 10.0 86 3.0 7.0 2.7 1 1 0 1 1 1 0 NADH(P)-binding Pyr_redox_2 PF07992.9 EKG22511.1 - 2.1e-06 27.7 0.0 2.3e-06 27.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_9_N PF15420.1 EKG22512.1 - 0.0038 17.0 0.3 0.0052 16.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta-hydrolase family N-terminus DsbD_2 PF13386.1 EKG22512.1 - 0.012 15.3 0.9 0.015 15.0 0.6 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF997 PF06196.7 EKG22512.1 - 0.087 12.3 0.3 0.087 12.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF1129 PF06570.6 EKG22512.1 - 0.089 12.0 0.7 0.12 11.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2975 PF11188.3 EKG22512.1 - 0.5 10.0 3.3 0.92 9.2 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Asp_protease_2 PF13650.1 EKG22513.1 - 0.00049 20.5 0.0 0.00085 19.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp PF00026.18 EKG22513.1 - 0.044 13.0 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease CitMHS PF03600.11 EKG22514.1 - 0.17 10.4 4.5 0.2 10.2 3.1 1.2 1 0 0 1 1 1 0 Citrate transporter I_LWEQ PF01608.12 EKG22514.1 - 6.5 6.6 9.5 0.26 11.2 1.8 1.9 2 0 0 2 2 2 0 I/LWEQ domain Catalase PF00199.14 EKG22516.1 - 2.2e-148 494.0 1.0 2.7e-148 493.7 0.7 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EKG22516.1 - 1.6e-13 50.2 0.1 3.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Ank_2 PF12796.2 EKG22519.1 - 1.4e-06 28.5 0.0 4.9e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EKG22519.1 - 5.5e-06 26.4 0.7 0.047 13.9 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EKG22519.1 - 0.00021 20.9 0.2 1.1 9.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EKG22519.1 - 0.0014 19.1 0.1 0.031 14.7 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EKG22519.1 - 0.0084 16.2 0.2 12 6.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat DJ-1_PfpI PF01965.19 EKG22520.1 - 1.6e-21 76.3 0.0 3e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EKG22520.1 - 6.4e-11 41.5 0.2 1.2e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family GATase_3 PF07685.9 EKG22520.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Aldo_ket_red PF00248.16 EKG22521.1 - 1.2e-62 211.2 0.0 1.7e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cu-oxidase_3 PF07732.10 EKG22522.1 - 1.8e-38 130.8 0.2 1.4e-37 128.0 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EKG22522.1 - 3.3e-19 69.3 0.1 4.5e-18 65.6 0.0 2.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EKG22522.1 - 5.1e-09 35.7 7.0 3.7e-08 32.9 0.8 3.6 2 2 1 3 3 3 1 Multicopper oxidase DUF2956 PF11169.3 EKG22522.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Phosphoesterase PF04185.9 EKG22523.1 - 9.8e-64 215.8 1.6 1.2e-63 215.5 1.1 1.0 1 0 0 1 1 1 1 Phosphoesterase family DUF754 PF05449.6 EKG22524.1 - 0.06 13.3 1.5 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF754) DoxX_3 PF13781.1 EKG22524.1 - 0.12 12.7 2.4 0.32 11.3 0.1 2.6 3 0 0 3 3 3 0 DoxX-like family DUF3159 PF11361.3 EKG22524.1 - 2.8 7.3 8.1 1.3 8.5 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3159) Amidohydro_2 PF04909.9 EKG22526.1 - 4e-17 62.6 0.1 6.5e-17 61.9 0.1 1.4 1 1 0 1 1 1 1 Amidohydrolase CgtA PF06306.6 EKG22528.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) MAP2_projctn PF08377.5 EKG22529.1 - 0.031 11.8 0.0 0.038 11.5 0.0 1.0 1 0 0 1 1 1 0 MAP2/Tau projection domain Cupin_1 PF00190.17 EKG22531.1 - 1.8e-12 46.8 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EKG22531.1 - 7.8e-09 34.9 0.0 1.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EKG22531.1 - 0.0014 18.0 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Fungal_trans PF04082.13 EKG22532.1 - 9.1e-13 47.6 2.4 9.1e-13 47.6 1.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG22532.1 - 3.6e-09 36.3 16.7 3.6e-09 36.3 11.6 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2051 PF09738.4 EKG22532.1 - 0.99 8.6 2.3 1.5 8.0 1.6 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) MFS_1 PF07690.11 EKG22533.1 - 7e-11 41.4 1.0 9.7e-11 40.9 0.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EKG22533.1 - 2.8e-05 22.8 0.3 3.8e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter SGL PF08450.7 EKG22535.1 - 3.7e-23 82.1 0.3 4.2e-12 45.9 0.1 3.0 3 1 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EKG22535.1 - 0.00059 19.8 0.0 0.0097 15.9 0.0 2.8 2 2 1 3 3 3 1 Strictosidine synthase TFIIIC_delta PF12657.2 EKG22535.1 - 0.025 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term TMEM71 PF15121.1 EKG22535.1 - 0.14 11.8 0.4 0.26 11.0 0.3 1.3 1 0 0 1 1 1 0 TMEM71 protein family Cytadhesin_P30 PF07271.6 EKG22536.1 - 0.067 12.4 1.0 0.075 12.3 0.7 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Zn_clus PF00172.13 EKG22537.1 - 4.7e-05 23.1 10.0 8.6e-05 22.3 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 EKG22538.1 - 2.5e-18 66.7 0.0 5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EKG22538.1 - 2.7e-18 66.3 0.5 7.5e-18 64.9 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EKG22538.1 - 6.8e-09 35.8 0.1 2.8e-08 33.8 0.1 2.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG22538.1 - 0.00052 19.7 0.1 0.0045 16.6 0.0 2.5 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EKG22538.1 - 0.053 13.6 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Citrate_synt PF00285.16 EKG22539.1 - 1.2e-17 63.7 0.0 2.1e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase MmgE_PrpD PF03972.9 EKG22540.1 - 7.9e-34 116.5 0.2 8.8e-34 116.4 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Acyl_transf_1 PF00698.16 EKG22541.1 - 1.5e-47 162.4 1.1 2.9e-34 118.8 0.0 3.7 3 1 1 4 4 4 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EKG22541.1 - 2e-32 111.1 1.0 4e-32 110.1 0.4 1.7 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EKG22541.1 - 1.9e-28 98.0 0.0 3.9e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EKG22541.1 - 3.8e-09 36.4 0.0 1.5e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EKG22541.1 - 0.00088 18.5 0.2 0.0068 15.6 0.1 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase AAA_16 PF13191.1 EKG22541.1 - 0.011 15.7 0.0 0.06 13.3 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 EKG22541.1 - 0.013 15.6 0.0 0.049 13.8 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EKG22541.1 - 0.072 12.9 1.0 0.65 9.8 0.3 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EKG22541.1 - 0.2 11.8 0.0 0.57 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF281 PF03436.8 EKG22541.1 - 0.35 10.9 0.9 0.99 9.5 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF281) DUF258 PF03193.11 EKG22541.1 - 0.59 9.2 0.0 1.2 8.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 EKG22541.1 - 1.5 7.3 0.0 2.3 6.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Transgly PF00912.17 EKG22542.1 - 0.076 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Transglycosylase DUF2225 PF09986.4 EKG22542.1 - 0.11 11.9 0.4 0.22 10.9 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF3827 PF12877.2 EKG22543.1 - 0.79 7.7 4.4 0.99 7.4 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Peptidase_M28 PF04389.12 EKG22544.1 - 1.2e-34 119.6 0.0 2e-34 118.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EKG22544.1 - 5.6e-14 51.6 0.2 1.5e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M42 PF05343.9 EKG22544.1 - 0.062 12.0 0.1 0.29 9.8 0.0 2.0 3 0 0 3 3 3 0 M42 glutamyl aminopeptidase GMC_oxred_N PF00732.14 EKG22545.1 - 1.4e-34 119.5 0.0 3.6e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EKG22545.1 - 3e-21 76.2 0.1 1.7e-20 73.7 0.2 2.3 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EKG22545.1 - 4.9e-09 35.5 2.2 6.4e-05 22.0 1.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EKG22545.1 - 1.8e-07 30.3 5.0 2e-06 26.9 2.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EKG22545.1 - 3.3e-06 27.0 0.6 1.5e-05 24.8 0.4 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EKG22545.1 - 1.9e-05 23.3 1.0 1.9e-05 23.3 0.7 2.6 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 EKG22545.1 - 0.00022 21.1 8.0 0.00042 20.2 0.7 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EKG22545.1 - 0.003 16.5 0.1 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EKG22545.1 - 0.0039 16.3 0.5 0.0039 16.3 0.3 2.9 3 0 0 3 3 3 1 Thi4 family Pyr_redox PF00070.22 EKG22545.1 - 0.04 14.3 3.2 0.17 12.3 0.5 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N_3 PF13417.1 EKG22546.1 - 1.3e-11 44.5 0.1 2.3e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EKG22546.1 - 0.00033 21.0 1.3 0.016 15.6 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EKG22546.1 - 0.0025 17.7 0.1 0.0069 16.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EKG22546.1 - 0.096 12.5 7.6 4.1 7.3 5.2 2.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AA_permease PF00324.16 EKG22547.1 - 2.1e-44 151.7 7.8 2.4e-44 151.5 5.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EKG22547.1 - 0.047 13.2 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Sugar_tr PF00083.19 EKG22549.1 - 8e-103 344.4 24.4 9.6e-103 344.1 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG22549.1 - 6.7e-29 100.7 52.2 2.1e-27 95.8 18.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EKG22549.1 - 0.013 13.6 7.4 0.25 9.3 1.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector GMC_oxred_C PF05199.8 EKG22550.1 - 1.9e-08 34.7 0.2 4.3e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EKG22550.1 - 0.00013 20.9 1.2 0.00013 20.9 0.8 1.8 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.14 EKG22550.1 - 0.00051 19.2 0.0 0.0014 17.8 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EKG22550.1 - 0.0031 16.4 0.3 0.0097 14.8 0.2 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EKG22550.1 - 0.0045 16.8 0.1 0.0094 15.8 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EKG22550.1 - 0.0068 15.5 0.2 0.011 14.8 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EKG22550.1 - 0.015 15.3 1.1 0.047 13.7 0.7 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EKG22550.1 - 0.035 14.5 0.2 0.095 13.1 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EKG22550.1 - 0.04 12.7 0.1 0.063 12.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EKG22550.1 - 0.053 11.9 0.5 0.11 10.9 0.4 1.5 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EKG22550.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GDI PF00996.13 EKG22550.1 - 0.37 9.0 0.0 0.54 8.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor DUF3433 PF11915.3 EKG22552.1 - 2.1e-07 31.0 0.5 2.1e-07 31.0 0.3 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) AAA PF00004.24 EKG22553.1 - 4e-21 75.5 0.0 1.3e-20 73.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EKG22553.1 - 0.00046 20.3 0.6 0.041 14.0 0.0 3.0 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EKG22553.1 - 0.00054 19.9 0.4 0.0026 17.7 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EKG22553.1 - 0.0013 18.6 0.0 0.14 11.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EKG22553.1 - 0.0024 18.6 0.1 0.018 15.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 EKG22553.1 - 0.0046 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EKG22553.1 - 0.0063 16.2 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EKG22553.1 - 0.0099 16.1 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EKG22553.1 - 0.026 14.8 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EKG22553.1 - 0.043 13.8 0.1 0.35 10.9 0.0 2.4 1 1 1 2 2 2 0 Sigma-54 interaction domain Hph PF13694.1 EKG22553.1 - 0.044 13.8 3.3 2.6 8.0 0.2 2.3 2 0 0 2 2 2 0 Sec63/Sec62 complex-interacting family Zeta_toxin PF06414.7 EKG22553.1 - 0.05 12.7 0.0 0.18 10.8 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EKG22553.1 - 0.057 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EKG22553.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.9 EKG22553.1 - 0.06 13.2 0.4 0.49 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Exonuc_VII_L PF02601.10 EKG22554.1 - 0.0053 15.9 1.0 0.046 12.9 0.1 2.2 2 0 0 2 2 2 1 Exonuclease VII, large subunit Baculo_PEP_C PF04513.7 EKG22554.1 - 0.04 13.7 0.6 0.65 9.8 0.1 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC-like PF12805.2 EKG22554.1 - 0.06 12.2 3.5 2.4 7.0 0.0 2.7 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS Erp_C PF06780.6 EKG22554.1 - 0.068 13.0 2.4 0.21 11.4 1.7 1.8 1 0 0 1 1 1 0 Erp protein C-terminus GST_C PF00043.20 EKG22554.1 - 0.1 12.6 1.4 9.6 6.2 0.0 3.4 4 0 0 4 4 4 0 Glutathione S-transferase, C-terminal domain DUF3734 PF12536.3 EKG22554.1 - 2 8.5 6.5 0.93 9.6 1.2 2.9 2 1 1 3 3 3 0 Patatin phospholipase OmpH PF03938.9 EKG22554.1 - 6.9 6.5 11.1 11 5.9 3.0 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DegS PF05384.6 EKG22558.1 - 0.0098 15.1 0.1 0.019 14.2 0.0 1.4 1 1 0 1 1 1 1 Sensor protein DegS Ribosomal_L29e PF01779.12 EKG22558.1 - 0.025 14.4 9.0 1.4 8.8 0.3 3.3 3 0 0 3 3 3 0 Ribosomal L29e protein family Syntaxin_2 PF14523.1 EKG22558.1 - 0.07 13.1 3.8 0.14 12.1 2.5 1.6 1 1 0 1 1 1 0 Syntaxin-like protein Effector_1 PF04518.7 EKG22558.1 - 0.23 10.4 2.4 0.38 9.6 1.5 1.5 1 1 0 1 1 1 0 Effector from type III secretion system Sipho_Gp157 PF05565.6 EKG22558.1 - 0.29 10.6 6.1 1.9 8.0 1.6 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 Ax_dynein_light PF10211.4 EKG22558.1 - 2.3 8.0 7.7 2.1 8.1 0.6 2.1 1 1 2 3 3 3 0 Axonemal dynein light chain Ecl1 PF12855.2 EKG22558.1 - 2.8 7.3 8.1 60 3.0 0.1 4.7 3 3 1 4 4 4 0 Life-span regulatory factor Syntaxin PF00804.20 EKG22558.1 - 4.4 7.5 5.9 9.1 6.5 4.1 1.6 1 1 0 1 1 1 0 Syntaxin HeH PF12949.2 EKG22559.1 - 0.049 13.1 0.0 48 3.6 0.0 3.6 4 0 0 4 4 4 0 HeH/LEM domain Peptidase_S15 PF02129.13 EKG22560.1 - 0.0087 15.5 0.3 0.0099 15.3 0.2 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) CPSF100_C PF13299.1 EKG22561.1 - 1.3e-44 152.2 0.0 1.3e-44 152.2 0.0 2.8 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EKG22561.1 - 7e-29 100.3 0.0 2.9e-28 98.3 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EKG22561.1 - 3.5e-09 36.3 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EKG22561.1 - 0.0038 16.9 0.3 0.019 14.6 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PGM_PMM_IV PF00408.15 EKG22561.1 - 0.022 14.7 0.0 0.072 13.1 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fungal_trans_2 PF11951.3 EKG22562.1 - 3.7e-59 200.2 0.1 5.8e-59 199.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EKG22562.1 - 1.2e-10 41.1 11.5 2e-10 40.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EKG22562.1 - 1.1 9.1 8.4 3.3 7.7 5.8 1.8 1 0 0 1 1 1 0 AT hook motif Syndecan PF01034.15 EKG22563.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain ABC_tran PF00005.22 EKG22564.1 - 3.3e-50 169.9 0.2 7.5e-24 84.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EKG22564.1 - 1.8e-44 151.4 43.2 1.5e-25 89.6 11.4 2.6 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 EKG22564.1 - 1.8e-18 67.5 3.7 8.5e-09 35.7 0.6 4.1 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EKG22564.1 - 9e-11 42.0 0.2 0.00033 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EKG22564.1 - 8.5e-09 34.9 0.1 0.0014 17.9 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EKG22564.1 - 1e-08 35.7 0.0 0.0008 19.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EKG22564.1 - 5.9e-08 32.3 0.0 0.0062 15.9 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EKG22564.1 - 6e-08 32.0 0.4 0.0053 16.2 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EKG22564.1 - 1.1e-07 31.3 0.0 0.054 12.5 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 EKG22564.1 - 1.3e-07 30.9 0.2 0.0094 15.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EKG22564.1 - 1.5e-07 31.5 0.2 0.017 15.2 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EKG22564.1 - 1e-06 29.5 0.0 0.1 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EKG22564.1 - 2.3e-06 27.2 1.1 0.02 14.3 0.0 2.8 3 0 0 3 3 2 2 AAA-like domain AAA_19 PF13245.1 EKG22564.1 - 2.9e-06 26.9 0.2 0.021 14.5 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain cobW PF02492.14 EKG22564.1 - 3.7e-06 26.5 0.7 0.067 12.6 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EKG22564.1 - 6.1e-06 25.9 0.1 0.14 11.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain T2SE PF00437.15 EKG22564.1 - 8.2e-06 24.9 0.0 0.078 11.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EKG22564.1 - 8.8e-06 25.3 0.4 0.014 14.8 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EKG22564.1 - 1.3e-05 25.0 0.0 0.044 13.4 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_28 PF13521.1 EKG22564.1 - 1.3e-05 25.2 0.3 0.045 13.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EKG22564.1 - 1.9e-05 24.9 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EKG22564.1 - 3.1e-05 23.8 0.0 0.4 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EKG22564.1 - 8.9e-05 22.2 0.4 0.49 10.0 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EKG22564.1 - 0.00011 22.4 0.0 0.46 10.6 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EKG22564.1 - 0.00013 21.8 1.0 1.4 8.8 0.0 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EKG22564.1 - 0.00016 20.8 0.1 0.041 12.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 EKG22564.1 - 0.00021 20.9 0.0 0.49 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.7 EKG22564.1 - 0.00027 20.5 0.0 0.00065 19.3 0.0 1.6 1 0 0 1 1 1 1 CDR ABC transporter NTPase_1 PF03266.10 EKG22564.1 - 0.00037 20.2 0.4 2.5 7.7 0.0 3.5 4 0 0 4 4 4 1 NTPase Pox_A32 PF04665.7 EKG22564.1 - 0.00056 19.2 0.6 0.66 9.2 0.1 2.3 2 0 0 2 2 2 2 Poxvirus A32 protein RNA_helicase PF00910.17 EKG22564.1 - 0.00068 19.7 0.2 0.51 10.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATP_bind_1 PF03029.12 EKG22564.1 - 0.00074 19.1 0.2 0.97 8.9 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EKG22564.1 - 0.00089 18.9 0.3 0.47 10.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EKG22564.1 - 0.002 18.0 0.0 0.77 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EKG22564.1 - 0.0024 17.2 0.1 0.32 10.3 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein UPF0079 PF02367.12 EKG22564.1 - 0.0033 17.0 0.1 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EKG22564.1 - 0.0065 16.0 0.7 0.51 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EKG22564.1 - 0.0074 15.1 0.1 0.5 9.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Miro PF08477.8 EKG22564.1 - 0.0087 16.5 0.1 2.5 8.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein SRP54 PF00448.17 EKG22564.1 - 0.0088 15.4 0.4 1.6 8.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 EKG22564.1 - 0.0098 15.8 1.7 2 8.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EKG22564.1 - 0.011 15.1 0.3 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EKG22564.1 - 0.014 14.3 0.0 2.1 7.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Septin PF00735.13 EKG22564.1 - 0.019 14.0 0.5 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Septin RuvB_N PF05496.7 EKG22564.1 - 0.019 14.0 0.1 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ABC_ATPase PF09818.4 EKG22564.1 - 0.023 13.3 0.2 0.74 8.3 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF2075 PF09848.4 EKG22564.1 - 0.039 12.9 0.1 1.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EKG22564.1 - 0.047 13.2 0.1 8.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 EKG22564.1 - 0.064 12.9 0.2 9.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.12 EKG22564.1 - 0.099 12.4 1.8 1.8 8.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 G-alpha PF00503.15 EKG22564.1 - 0.16 10.6 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit PhoH PF02562.11 EKG22564.1 - 0.17 11.0 0.1 13 4.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SRPRB PF09439.5 EKG22564.1 - 0.18 10.9 0.2 4 6.6 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Bac_DnaA PF00308.13 EKG22564.1 - 0.25 10.9 0.1 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Thymidylate_kin PF02223.12 EKG22564.1 - 0.69 9.2 1.9 30 3.9 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Cu_amine_oxid PF01179.15 EKG22565.1 - 8e-159 528.7 0.0 1e-158 528.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EKG22565.1 - 1.1e-13 51.0 0.0 2.3e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EKG22565.1 - 1.4e-06 28.2 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain FAD_binding_3 PF01494.14 EKG22567.1 - 2.2e-22 79.6 0.1 6e-22 78.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EKG22567.1 - 2.9e-05 23.3 0.0 0.01 14.9 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EKG22567.1 - 0.0015 17.5 0.5 1.8 7.3 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.22 EKG22567.1 - 0.011 16.1 0.8 0.093 13.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG22567.1 - 0.026 13.4 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 EKG22567.1 - 0.073 11.8 0.0 7.8 5.2 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase Asp PF00026.18 EKG22569.1 - 4.8e-16 58.8 0.0 6.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.10 EKG22569.1 - 0.0094 15.4 1.8 0.021 14.3 1.3 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 TAXi_N PF14543.1 EKG22569.1 - 0.012 15.5 0.0 0.17 11.7 0.0 2.6 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal EphA2_TM PF14575.1 EKG22569.1 - 0.025 14.9 0.1 0.045 14.1 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Amnionless PF14828.1 EKG22569.1 - 0.029 12.8 0.0 0.043 12.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless SKG6 PF08693.5 EKG22569.1 - 0.031 13.5 3.3 0.058 12.7 2.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.8 EKG22569.1 - 0.044 12.4 2.2 0.076 11.6 1.5 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein IncA PF04156.9 EKG22569.1 - 0.089 12.3 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 IncA protein Rifin_STEVOR PF02009.11 EKG22569.1 - 0.21 11.1 0.2 0.33 10.5 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family MtrF PF09472.5 EKG22569.1 - 1 8.6 6.6 2 7.7 4.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Abhydrolase_6 PF12697.2 EKG22570.1 - 0.00018 21.4 0.1 0.00042 20.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EKG22570.1 - 0.0035 17.1 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Kdo PF06293.9 EKG22570.1 - 0.012 14.6 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGAP1 PF07819.8 EKG22570.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Pkinase PF00069.20 EKG22570.1 - 0.025 13.7 0.0 0.068 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein kinase domain DUF676 PF05057.9 EKG22570.1 - 0.046 13.0 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peroxidase_2 PF01328.12 EKG22572.1 - 3.7e-40 137.5 0.1 4.5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 HhH-GPD PF00730.20 EKG22575.1 - 4e-06 27.0 0.0 8.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3328 PF11807.3 EKG22578.1 - 3.2e-26 92.3 0.0 4.2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EKG22579.1 - 4e-30 105.1 0.1 7.1e-30 104.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.1 EKG22580.1 - 7e-21 74.8 0.0 8.3e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG22580.1 - 2.3e-05 24.3 0.0 0.00031 20.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EKG22580.1 - 0.025 14.3 0.1 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_7 PF13508.1 EKG22580.1 - 0.036 14.2 0.0 0.43 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKG22580.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ODC_AZ PF02100.12 EKG22580.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Ornithine decarboxylase antizyme DUF3328 PF11807.3 EKG22581.1 - 2.4e-43 148.3 0.1 3.2e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Couple_hipA PF13657.1 EKG22581.1 - 0.029 14.6 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 HipA N-terminal domain 2OG-FeII_Oxy_3 PF13640.1 EKG22582.1 - 2.5e-06 27.9 0.0 1e-05 25.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EKG22582.1 - 0.00026 21.2 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CHAP PF05257.11 EKG22582.1 - 0.32 10.6 1.6 0.6 9.7 1.1 1.3 1 0 0 1 1 1 0 CHAP domain LAT PF15234.1 EKG22583.1 - 0.049 13.1 12.8 0.36 10.2 0.5 2.9 1 1 2 3 3 3 0 Linker for activation of T-cells Cytochrome_cB PF11783.3 EKG22583.1 - 0.51 9.8 24.4 5.6 6.5 3.2 3.8 1 1 2 3 3 3 0 Cytochrome c bacterial Acetyltransf_3 PF13302.1 EKG22584.1 - 3.9e-13 49.7 0.0 4.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EKG22584.1 - 1.7e-12 47.2 0.0 2.7e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EKG22584.1 - 4.9e-09 36.3 0.0 6.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EKG22584.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EKG22584.1 - 0.0013 18.5 0.0 0.0085 15.9 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EKG22584.1 - 0.036 13.8 0.1 0.24 11.1 0.1 2.2 2 1 0 2 2 2 0 FR47-like protein adh_short PF00106.20 EKG22585.1 - 7.1e-08 32.5 0.2 8.4e-08 32.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EKG22585.1 - 2.2e-06 27.4 0.1 2.4e-06 27.3 0.1 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EKG22585.1 - 0.0045 16.4 0.0 0.0054 16.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EKG22585.1 - 0.051 12.4 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein CoA_transf_3 PF02515.12 EKG22587.1 - 2.7e-43 147.4 0.1 1.1e-41 142.2 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III TatD_DNase PF01026.16 EKG22588.1 - 5.8e-39 133.8 0.0 7.1e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase p450 PF00067.17 EKG22589.1 - 3.3e-60 203.9 0.0 4.3e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EKG22590.1 - 1.2e-09 37.2 0.1 2.4e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EKG22591.1 - 2.6e-103 346.0 30.0 3.1e-103 345.7 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EKG22591.1 - 3.7e-29 101.5 25.3 3.7e-29 101.5 17.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.15 EKG22591.1 - 0.025 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF3325 PF11804.3 EKG22591.1 - 0.33 10.8 0.1 0.33 10.8 0.0 4.0 3 1 2 5 5 5 0 Protein of unknown function (DUF3325) PIRT PF15099.1 EKG22591.1 - 4.4 6.5 9.0 0.43 9.7 0.3 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Helicase_C_2 PF13307.1 EKG22592.1 - 4.7e-53 179.5 0.0 1.3e-52 178.0 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EKG22592.1 - 5.9e-45 152.7 0.0 1.7e-44 151.2 0.0 1.8 1 1 0 1 1 1 1 DEAD_2 His_biosynth PF00977.16 EKG22593.1 - 1.4e-44 152.0 0.0 7.5e-44 149.6 0.0 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EKG22593.1 - 1.8e-13 50.3 0.0 2.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SOR_SNZ PF01680.12 EKG22593.1 - 0.065 12.8 0.0 0.99 8.9 0.0 2.3 2 0 0 2 2 2 0 SOR/SNZ family Dus PF01207.12 EKG22593.1 - 0.11 11.2 0.0 0.26 10.0 0.0 1.5 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) WD40 PF00400.27 EKG22594.1 - 9.9e-47 155.2 21.8 2.7e-08 33.3 0.4 9.4 9 0 0 9 9 9 8 WD domain, G-beta repeat PQQ_3 PF13570.1 EKG22594.1 - 3.1e-05 24.0 13.3 0.38 11.0 0.0 7.1 6 2 1 7 7 7 2 PQQ-like domain Coatomer_WDAD PF04053.9 EKG22594.1 - 0.00027 19.8 0.0 0.74 8.5 0.0 3.2 2 1 1 3 3 3 2 Coatomer WD associated region eIF2A PF08662.6 EKG22594.1 - 0.00062 19.5 0.5 0.14 11.8 0.0 3.4 2 2 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EKG22594.1 - 0.017 13.2 4.8 0.046 11.8 0.1 2.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 PQQ PF01011.16 EKG22594.1 - 0.19 11.3 5.0 22 4.7 0.1 4.4 4 0 0 4 4 4 0 PQQ enzyme repeat AA_permease PF00324.16 EKG22595.1 - 3.2e-123 411.5 37.7 3.7e-123 411.3 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EKG22595.1 - 6.2e-29 100.7 43.7 8.6e-29 100.3 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease COesterase PF00135.23 EKG22596.1 - 2.1e-65 221.4 0.0 2.6e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EKG22596.1 - 6.1e-09 35.7 2.2 2.7e-08 33.6 0.4 2.6 3 1 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG22596.1 - 0.0036 17.0 0.1 0.0054 16.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EKG22596.1 - 0.013 14.7 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family SNF2_N PF00176.18 EKG22600.1 - 1.5e-67 227.5 0.0 2e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EKG22600.1 - 1.7e-64 217.2 3.3 3.9e-64 216.0 2.3 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EKG22600.1 - 4.1e-13 48.9 0.0 1.5e-12 47.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EKG22600.1 - 0.00024 20.9 0.0 0.00057 19.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EKG22600.1 - 0.00027 19.8 0.0 0.0031 16.3 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 EKG22600.1 - 0.03 14.4 0.0 0.35 10.9 0.0 2.7 2 1 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 EKG22601.1 - 5.9e-25 88.4 0.3 7e-25 88.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EKG22601.1 - 6.6e-14 52.0 0.1 5.7e-13 48.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EKG22601.1 - 3.2e-11 43.1 0.3 2.5e-10 40.2 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EKG22601.1 - 0.00016 20.9 0.1 0.088 12.0 0.0 2.5 3 0 0 3 3 3 2 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EKG22601.1 - 0.00027 20.2 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PhoPQ_related PF10142.4 EKG22601.1 - 0.0021 16.6 0.0 0.0032 15.9 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.8 EKG22601.1 - 0.012 15.1 0.1 0.13 11.6 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.15 EKG22601.1 - 0.013 15.7 0.0 0.019 15.2 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain BAAT_C PF08840.6 EKG22601.1 - 0.042 13.5 0.1 0.38 10.4 0.0 2.2 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EKG22601.1 - 0.062 12.7 0.0 0.29 10.5 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EKG22601.1 - 0.088 12.6 0.4 0.28 11.0 0.3 1.9 1 1 0 1 1 1 0 Putative lysophospholipase Chitin_synth_2 PF03142.10 EKG22605.1 - 3.1e-15 55.5 0.0 4.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EKG22605.1 - 1.5e-12 47.6 0.2 1.5e-11 44.3 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EKG22605.1 - 6.2e-11 42.5 0.0 2.9e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EKG22605.1 - 1.7e-07 30.7 0.6 0.00027 20.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EKG22605.1 - 0.00016 21.3 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 AdoHcyase PF05221.12 EKG22605.1 - 0.0066 15.4 0.0 0.014 14.3 0.0 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase DUF188 PF02639.9 EKG22605.1 - 0.051 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 PAN_4 PF14295.1 EKG22606.1 - 0.0011 18.5 1.5 0.0024 17.5 1.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EKG22606.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 PAN domain PAN_3 PF08277.7 EKG22606.1 - 0.072 12.7 0.2 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 PAN-like domain ABC_membrane PF00664.18 EKG22611.1 - 8.4e-36 123.7 14.2 1.2e-35 123.3 9.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EKG22611.1 - 3.7e-33 114.7 0.0 7.6e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EKG22611.1 - 2.8e-08 33.9 0.5 9.5e-07 28.9 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.14 EKG22611.1 - 2.1e-06 27.1 0.0 0.00051 19.3 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EKG22611.1 - 8.4e-06 25.9 0.0 0.17 11.8 0.0 2.4 1 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EKG22611.1 - 0.00026 20.8 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EKG22611.1 - 0.00045 20.3 0.0 0.0028 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EKG22611.1 - 0.0011 19.7 0.0 0.0023 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EKG22611.1 - 0.0011 18.1 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 EKG22611.1 - 0.0014 18.8 0.0 0.0094 16.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EKG22611.1 - 0.0057 16.1 0.0 0.017 14.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EKG22611.1 - 0.016 15.4 0.0 0.072 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EKG22611.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 EKG22611.1 - 0.023 13.8 0.0 0.077 12.0 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EKG22611.1 - 0.029 13.7 0.1 0.074 12.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EKG22611.1 - 0.029 14.2 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EKG22611.1 - 0.034 13.5 0.1 0.14 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EKG22611.1 - 0.067 13.1 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rad17 PF03215.10 EKG22611.1 - 0.081 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TPR_1 PF00515.23 EKG22611.1 - 0.2 11.3 0.8 0.68 9.6 0.5 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_23 PF13476.1 EKG22611.1 - 0.2 11.9 0.2 0.49 10.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AIM24 PF01987.12 EKG22612.1 - 2.5e-49 167.6 0.0 3.3e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EKG22612.1 - 0.011 16.2 0.1 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) WD40 PF00400.27 EKG22613.1 - 4.9e-108 349.5 29.6 3.5e-12 45.6 0.0 11.7 11 1 1 12 12 12 10 WD domain, G-beta repeat Nup160 PF11715.3 EKG22613.1 - 1.2e-14 53.4 16.8 0.014 13.5 0.1 7.6 2 2 5 7 7 7 7 Nucleoporin Nup120/160 eIF2A PF08662.6 EKG22613.1 - 1.8e-14 53.9 0.0 0.024 14.3 0.0 4.7 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EKG22613.1 - 4e-11 42.0 0.1 0.65 9.3 0.0 7.5 7 0 0 7 7 7 4 Proteasome subunit A N-terminal signature SGL PF08450.7 EKG22613.1 - 2.8e-07 30.1 0.1 0.0025 17.2 0.0 3.5 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 EKG22613.1 - 1.3e-06 27.4 1.1 0.04 12.6 0.1 5.3 1 1 2 5 5 5 1 Nup133 N terminal like Apc4_WD40 PF12894.2 EKG22613.1 - 4.2e-05 22.9 0.0 42 3.7 0.0 6.2 8 0 0 8 8 8 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EKG22613.1 - 9e-05 22.0 3.8 25 4.6 0.0 7.1 8 0 0 8 8 7 0 WD40-like Beta Propeller Repeat TruB_C PF09142.6 EKG22613.1 - 0.0058 16.2 1.4 58 3.4 0.0 5.5 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal DUF1258 PF06869.7 EKG22613.1 - 0.0064 15.6 0.2 1.2 8.1 0.0 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1258) DUF1018 PF06252.7 EKG22613.1 - 0.048 14.1 0.1 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) DPPIV_N PF00930.16 EKG22613.1 - 0.049 12.2 0.5 24 3.3 0.0 4.3 5 1 0 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.11 EKG22613.1 - 0.052 11.8 0.0 12 4.0 0.0 3.5 3 1 0 4 4 4 0 Cytochrome D1 heme domain Nbas_N PF15492.1 EKG22613.1 - 0.073 12.1 10.2 30 3.5 0.0 6.2 3 3 3 7 7 7 0 Neuroblastoma-amplified sequence, N terminal Methyltransf_3 PF01596.12 EKG22613.1 - 0.086 11.8 0.0 21 4.0 0.0 3.6 4 1 1 5 5 5 0 O-methyltransferase Pyr_redox PF00070.22 EKG22615.1 - 2.2e-09 37.6 0.0 4.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EKG22615.1 - 0.0015 18.4 0.2 1.4 8.7 0.7 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EKG22615.1 - 0.021 13.6 1.5 0.035 12.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain AMP-binding PF00501.23 EKG22616.1 - 5.8e-40 136.9 0.0 8.8e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EKG22616.1 - 1.8e-29 102.5 0.0 3.1e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EKG22616.1 - 0.00036 20.7 0.0 0.00098 19.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2628 PF10947.3 EKG22616.1 - 0.081 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) GST_N_2 PF13409.1 EKG22617.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EKG22617.1 - 0.0071 16.5 0.0 0.014 15.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EKG22617.1 - 0.011 15.8 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Prenyltrans_1 PF13243.1 EKG22617.1 - 0.045 13.7 0.4 0.07 13.1 0.3 1.3 1 0 0 1 1 1 0 Prenyltransferase-like DUF2997 PF11211.3 EKG22617.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) Methyltransf_2 PF00891.13 EKG22618.1 - 2.2e-36 125.2 0.0 2.5e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EKG22618.1 - 0.0016 18.2 0.0 0.0031 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EKG22619.1 - 1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EKG22619.1 - 2.3e-07 30.5 0.0 4.3e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EKG22619.1 - 9.5e-05 22.9 0.0 0.00068 20.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EKG22619.1 - 0.0038 17.6 0.0 0.0092 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EKG22619.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) p450 PF00067.17 EKG22620.1 - 1.6e-13 49.9 0.0 2.3e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 DUF3357 PF11837.3 EKG22622.1 - 0.019 14.7 0.1 4 7.3 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF3377 PF11857.3 EKG22622.1 - 0.089 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) p450 PF00067.17 EKG22624.1 - 9.5e-14 50.7 0.0 1.2e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1294 PF06961.8 EKG22624.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) Phage_TAC PF06222.6 EKG22625.1 - 0.12 11.9 0.3 0.21 11.1 0.2 1.4 1 1 0 1 1 1 0 Phage tail assembly chaperone MBOAT_2 PF13813.1 EKG22626.1 - 1e-19 70.3 5.1 2.7e-19 69.0 3.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Aminotran_1_2 PF00155.16 EKG22627.1 - 3.3e-45 154.5 0.0 4e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EKG22627.1 - 9.5e-05 21.6 0.0 0.00018 20.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase ABC_membrane PF00664.18 EKG22628.1 - 1e-09 38.2 2.7 1.4e-09 37.8 1.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region Methyltransf_2 PF00891.13 EKG22630.1 - 5.8e-27 94.4 0.0 8e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EKG22630.1 - 0.039 14.3 0.0 0.099 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EKG22631.1 - 0.00036 20.4 2.4 0.00083 19.3 1.7 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EKG22631.1 - 0.0048 16.3 0.1 0.0078 15.6 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Reovirus_cap PF00979.12 EKG22631.1 - 0.042 12.7 0.0 0.049 12.5 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Aminotran_1_2 PF00155.16 EKG22632.1 - 5.8e-39 134.0 0.0 7.5e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DOMON PF03351.12 EKG22633.1 - 2e-05 24.5 0.9 4.2e-05 23.4 0.6 1.5 1 0 0 1 1 1 1 DOMON domain DUF2712 PF10916.3 EKG22633.1 - 0.0022 17.9 0.1 0.0038 17.2 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2712) Kelch_5 PF13854.1 EKG22634.1 - 5.3e-10 39.0 2.0 2e-09 37.1 0.1 2.7 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.1 EKG22634.1 - 4.8e-07 29.7 19.5 1.4e-06 28.2 0.7 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EKG22634.1 - 0.001 18.8 18.5 0.0059 16.3 0.0 5.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EKG22634.1 - 0.12 11.9 2.2 2.7 7.6 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Mito_fiss_reg PF05308.6 EKG22634.1 - 3.8 6.7 5.2 6.3 6.0 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EKG22634.1 - 7.9 5.6 5.2 14 4.8 3.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pyr_redox_2 PF07992.9 EKG22635.1 - 4.8e-10 39.6 0.0 6.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EKG22635.1 - 2.7e-07 30.4 0.4 0.0014 18.3 0.0 2.1 1 1 1 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EKG22635.1 - 5.7e-06 26.5 0.0 0.019 15.0 0.0 2.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EKG22635.1 - 9.5e-06 24.8 0.0 9.5e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EKG22635.1 - 3.8e-05 22.9 0.0 5.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EKG22635.1 - 4.1e-05 22.2 0.1 0.0018 16.8 0.0 2.0 1 1 1 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 EKG22635.1 - 0.00012 21.1 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EKG22635.1 - 0.00018 21.4 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EKG22635.1 - 0.00025 20.0 0.0 0.00033 19.6 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase XdhC_C PF13478.1 EKG22635.1 - 0.0011 19.2 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 XdhC Rossmann domain FAD_binding_2 PF00890.19 EKG22635.1 - 0.005 15.7 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EKG22635.1 - 0.0069 15.2 0.1 0.033 13.0 0.0 1.8 1 1 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EKG22635.1 - 0.0081 15.1 0.1 0.017 14.0 0.1 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EKG22635.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase p450 PF00067.17 EKG22637.1 - 4.4e-08 32.0 0.0 5.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EKG22638.1 - 3.9e-41 141.0 0.0 4.6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M19 PF01244.16 EKG22639.1 - 1e-97 326.9 0.0 1.2e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) MBOAT_2 PF13813.1 EKG22642.1 - 1.1e-18 67.0 0.7 3.9e-18 65.3 0.5 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family p450 PF00067.17 EKG22643.1 - 2e-30 105.7 0.0 2.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1857 PF08982.6 EKG22644.1 - 5.2e-22 78.0 0.0 6e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Pyr_redox_2 PF07992.9 EKG22645.1 - 2.1e-15 57.1 0.0 2.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EKG22645.1 - 8.4e-06 24.9 0.0 1.3e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EKG22645.1 - 9e-05 22.2 0.1 0.41 10.4 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EKG22645.1 - 0.00034 19.2 0.0 0.0042 15.5 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EKG22645.1 - 0.00048 20.0 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EKG22645.1 - 0.00075 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EKG22645.1 - 0.00076 18.4 0.1 0.0015 17.4 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Cytochrom_C PF00034.16 EKG22645.1 - 0.0012 19.6 0.0 0.0024 18.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c Thi4 PF01946.12 EKG22645.1 - 0.037 13.1 0.1 0.066 12.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EKG22645.1 - 0.14 12.2 0.0 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase