# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Mito_carr PF00153.27 ORY36266.1 - 2.1e-08 34.0 0.1 2.5e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein NAD_Gly3P_dh_N PF01210.23 ORY36422.1 - 9.9e-51 171.8 0.1 1.5e-50 171.2 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORY36422.1 - 7.7e-35 120.2 1.4 1.6e-34 119.2 1.4 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 ORY36422.1 - 0.0012 19.4 0.0 0.48 11.0 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent ABC_tran PF00005.27 ORY36565.1 - 8.8e-13 49.0 0.0 9.9e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY36565.1 - 0.0016 17.9 0.4 0.1 12.1 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY36565.1 - 0.0079 15.9 0.2 0.016 15.0 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY36565.1 - 0.0089 15.6 1.1 0.025 14.2 0.6 1.8 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 ORY36565.1 - 0.013 16.0 0.2 0.021 15.3 0.2 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY36565.1 - 0.032 13.3 0.3 0.046 12.8 0.3 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORY36565.1 - 0.043 13.9 0.0 0.053 13.6 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 ORY36565.1 - 0.049 13.4 0.1 0.065 13.0 0.1 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 ORY36565.1 - 0.062 12.6 0.3 1.3 8.3 0.3 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 ORY36565.1 - 0.079 13.0 0.2 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Dynamin family AAA_21 PF13304.6 ORY36565.1 - 0.095 12.5 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY36565.1 - 0.13 12.1 0.3 0.2 11.6 0.3 1.2 1 0 0 1 1 1 0 RsgA GTPase SRP_SPB PF02978.19 ORY36619.1 - 1e-34 119.1 1.5 1.7e-34 118.4 1.5 1.4 1 0 0 1 1 1 1 Signal peptide binding domain IU_nuc_hydro PF01156.19 ORY36760.1 - 9.9e-45 153.4 0.0 1.7e-44 152.7 0.0 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Abhydrolase_6 PF12697.7 ORY36942.1 - 2e-07 31.8 0.9 2e-07 31.8 0.9 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY36942.1 - 0.075 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold HhH-GPD PF00730.25 ORY37173.1 - 4.3e-21 75.4 0.0 7.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY37173.1 - 3.4e-06 26.6 0.2 6.9e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ORY37173.1 - 0.024 15.2 0.0 4.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 ORY37173.1 - 0.031 14.4 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif MINDY_DUB PF04424.13 ORY37174.1 - 4e-29 101.0 0.0 1.1e-28 99.5 0.0 1.7 2 0 0 2 2 2 1 MINDY deubiquitinase Activator-TraM PF11657.8 ORY37175.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Transcriptional activator TraM Nipped-B_C PF12830.7 ORY37374.1 - 8.7e-38 130.2 4.5 2.5e-37 128.7 0.3 3.6 4 1 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 ORY37374.1 - 4e-11 43.0 0.5 1.5e-08 34.8 0.2 3.0 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 ORY37374.1 - 6.9e-05 21.6 4.0 0.02 13.5 0.1 3.3 3 1 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.6 ORY37374.1 - 7.9e-05 23.0 0.8 0.0072 16.7 0.1 4.4 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 ORY37374.1 - 0.00066 19.7 0.2 0.45 10.9 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat DUF3387 PF11867.8 ORY37374.1 - 0.0084 15.5 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3387) Cnd1 PF12717.7 ORY37374.1 - 0.011 15.8 0.2 0.67 10.0 0.1 3.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 ORY37374.1 - 0.044 13.0 0.0 3.9 6.6 0.0 3.1 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Kelch_5 PF13854.6 ORY37375.1 - 2.4e-31 107.2 11.0 2e-06 27.7 0.4 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 ORY37375.1 - 1.8e-26 91.5 11.7 1.4e-09 37.3 2.9 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 ORY37375.1 - 4.1e-26 90.3 12.0 8e-08 32.3 1.5 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 ORY37375.1 - 1.4e-25 89.0 18.2 1.2e-05 25.2 0.0 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY37375.1 - 6e-25 87.0 17.3 3.6e-08 33.5 0.4 7.3 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY37375.1 - 5.9e-23 79.9 10.3 0.0025 17.7 0.0 6.7 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.14 ORY37375.1 - 0.025 13.6 0.5 24 3.8 0.0 4.0 3 1 2 5 5 5 0 Recombination activating protein 2 LexA_DNA_bind PF01726.16 ORY37504.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Spuma_A9PTase PF03539.14 ORY37504.1 - 0.064 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) zf-CCHC PF00098.23 ORY37505.1 - 6.3e-07 29.2 1.0 1e-06 28.5 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 ORY37505.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 ORY37505.1 - 0.87 9.3 3.5 1.6 8.5 1.3 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger PALP PF00291.25 ORY37557.1 - 4.9e-78 262.5 0.2 7.3e-78 262.0 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ORY37557.1 - 9.3e-36 121.5 0.1 1.4e-21 76.1 0.0 3.6 4 0 0 4 4 4 3 C-terminal regulatory domain of Threonine dehydratase F-box-like PF12937.7 ORY37558.1 - 2.5e-09 36.9 0.0 5.9e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY37558.1 - 6.1e-07 29.2 0.0 1.5e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain Lactamase_B_2 PF12706.7 ORY37559.1 - 1e-09 38.2 0.0 0.00052 19.6 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY37559.1 - 8.7e-07 29.1 0.0 2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 ORY37559.1 - 2.4e-06 27.1 0.0 4.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease PDEase_II PF02112.15 ORY37559.1 - 0.08 12.0 0.3 0.16 11.0 0.1 1.5 2 0 0 2 2 2 0 cAMP phosphodiesterases class-II DUF3787 PF12655.7 ORY37702.1 - 0.19 11.7 0.3 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) AAA PF00004.29 ORY37703.1 - 1.1e-15 58.2 0.0 2.4e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY37703.1 - 5.6e-09 36.6 0.0 3.6e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY37703.1 - 3.3e-07 30.6 0.0 7.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY37703.1 - 0.0007 19.9 0.1 0.0037 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY37703.1 - 0.0033 17.2 0.0 0.0074 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_lid_10 PF17872.1 ORY37703.1 - 0.0035 17.4 0.1 0.0063 16.6 0.1 1.3 1 0 0 1 1 1 1 AAA lid domain DUF2075 PF09848.9 ORY37703.1 - 0.0074 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 ORY37703.1 - 0.01 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY37703.1 - 0.052 13.5 0.1 1.5 8.7 0.1 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ORY37703.1 - 0.071 13.0 0.0 0.69 9.8 0.0 2.1 2 0 0 2 2 2 0 NTPase NACHT PF05729.12 ORY37703.1 - 0.074 13.0 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.13 ORY37703.1 - 0.083 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 ORY37703.1 - 0.094 12.9 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY37703.1 - 0.14 12.5 0.0 0.7 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 ORY37703.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Shugoshin_C PF07557.11 ORY37757.1 - 2.5e-10 40.0 3.3 2.5e-10 40.0 3.3 2.4 2 0 0 2 2 2 1 Shugoshin C terminus PBP1_TM PF14812.6 ORY37757.1 - 0.029 14.8 5.7 0.041 14.3 2.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAM_LAG1_CLN8 PF03798.16 ORY37830.1 - 2.9e-17 63.1 0.4 2.9e-17 63.1 0.4 1.3 2 0 0 2 2 2 1 TLC domain F-box-like PF12937.7 ORY37831.1 - 4e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY37831.1 - 0.013 15.4 1.0 0.043 13.7 0.1 2.4 2 1 0 2 2 2 0 F-box domain DUF2510 PF10708.9 ORY37831.1 - 0.55 10.0 3.2 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) DUF2890 PF11081.8 ORY37832.1 - 0.13 12.4 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) GTP1_OBG PF01018.22 ORY37833.1 - 0.51 9.9 5.6 1 9.0 5.6 1.4 1 0 0 1 1 1 0 GTP1/OBG SPX PF03105.19 ORY37833.1 - 1.8 8.4 9.3 2 8.2 9.3 1.1 1 0 0 1 1 1 0 SPX domain Dimerisation PF08100.11 ORY37881.1 - 0.00014 21.8 0.1 0.00033 20.6 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.7 ORY37881.1 - 0.035 14.0 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 MarR family MarR PF01047.22 ORY37881.1 - 0.091 12.7 0.0 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 MarR family RPA_C PF08784.11 ORY37881.1 - 0.14 12.8 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 Replication protein A C terminal DAO PF01266.24 ORY37882.1 - 1e-61 209.5 3.9 1.2e-61 209.3 3.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY37882.1 - 6.3e-05 23.0 2.7 0.022 14.7 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ORY37882.1 - 0.0002 20.7 3.4 0.078 12.2 0.8 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY37882.1 - 0.00095 19.3 2.3 0.0021 18.2 1.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY37882.1 - 0.022 13.6 4.6 0.1 11.4 2.8 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 ORY37882.1 - 0.15 12.6 1.8 0.55 10.8 0.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.7 ORY37883.1 - 3.1e-06 27.0 1.6 5.3e-06 26.2 1.6 1.3 1 0 0 1 1 1 1 F-box-like Rad1 PF02144.16 ORY37884.1 - 1.4e-84 283.4 0.0 1.7e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Amidase PF01425.21 ORY38055.1 - 2e-45 155.6 0.1 2.4e-44 152.0 0.4 2.3 2 1 0 2 2 2 1 Amidase Pkinase PF00069.25 ORY38056.1 - 1.3e-70 237.8 0.0 1.5e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38056.1 - 1e-41 143.0 0.0 1.2e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY38056.1 - 7.8e-09 35.3 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY38056.1 - 0.00065 19.7 0.3 0.0021 18.0 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY38056.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY38056.1 - 0.0093 14.9 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY38056.1 - 0.011 15.1 0.1 0.015 14.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_T7_Capsid PF05396.11 ORY38056.1 - 0.053 13.9 0.0 0.087 13.2 0.0 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein Pkinase_fungal PF17667.1 ORY38056.1 - 0.097 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ICL PF00463.21 ORY38061.1 - 9.7e-183 608.4 0.3 1.1e-182 608.2 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Aa_trans PF01490.18 ORY38062.1 - 2e-37 128.9 26.5 2.3e-37 128.7 26.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 ORY38062.1 - 5.4e-07 28.6 10.2 5.4e-07 28.6 10.2 2.3 3 0 0 3 3 3 1 Amino acid permease stn_TNFRSF12A PF12191.8 ORY38063.1 - 0.02 15.1 0.8 7.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CX9C PF16860.5 ORY38105.1 - 0.00011 22.2 1.0 0.24 11.4 0.3 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 ORY38105.1 - 0.00037 20.7 0.9 0.00085 19.5 0.9 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.10 ORY38105.1 - 0.0034 17.4 1.2 6.8 6.8 0.0 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.11 ORY38105.1 - 0.028 14.8 2.3 0.033 14.6 1.0 1.7 1 1 1 2 2 2 0 GCK domain RhoGEF PF00621.20 ORY38107.1 - 4.9e-38 131.2 0.0 9e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 ORY38107.1 - 2.6e-16 59.2 0.6 5.7e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PH_13 PF16652.5 ORY38107.1 - 5.1e-15 55.6 0.1 1.3e-13 51.1 0.1 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_1 PF00018.28 ORY38107.1 - 5.3e-15 54.8 0.8 1.7e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain WH2 PF02205.20 ORY38107.1 - 1.7e-08 34.0 1.2 3.7e-08 32.9 1.2 1.6 1 0 0 1 1 1 1 WH2 motif SH3_2 PF07653.17 ORY38107.1 - 3.4e-06 26.6 0.0 0.02 14.5 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF919 PF06034.11 ORY38107.1 - 0.0065 16.3 1.7 0.024 14.5 1.7 1.9 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF919) PH_5 PF15405.6 ORY38107.1 - 0.039 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PS_Dcarbxylase PF02666.15 ORY38316.1 - 8.7e-74 247.4 0.0 9.8e-72 240.7 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase F-box-like PF12937.7 ORY38317.1 - 4.9e-06 26.3 0.1 1.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like PhageMin_Tail PF10145.9 ORY38317.1 - 0.17 11.7 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 Phage-related minor tail protein DUF4337 PF14235.6 ORY38319.1 - 0.15 12.1 4.8 0.21 11.7 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4203 PF13886.6 ORY38508.1 - 1.8e-12 47.4 17.7 2.3e-12 47.0 17.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) ATP_bind_3 PF01171.20 ORY38509.1 - 3.1e-39 134.6 0.0 4.1e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 ORY38509.1 - 0.003 17.3 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase PAPS_reduct PF01507.19 ORY38509.1 - 0.037 14.1 0.0 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family F-box-like PF12937.7 ORY38510.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 F-box-like WD40 PF00400.32 ORY38511.1 - 0.094 13.6 5.3 35 5.5 0.2 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat DOR PF14839.6 ORY38511.1 - 0.22 11.5 3.8 2.1 8.2 1.8 2.2 1 1 1 2 2 2 0 DOR family Kelch_1 PF01344.25 ORY38743.1 - 2.4e-29 100.7 5.6 2.1e-10 40.0 2.9 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 ORY38743.1 - 5.9e-29 99.6 5.9 3e-07 30.3 0.4 5.2 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 ORY38743.1 - 4.9e-27 93.6 7.4 5e-09 36.2 0.4 6.0 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY38743.1 - 7.1e-26 89.6 8.1 1.1e-08 35.1 1.5 5.2 3 2 2 5 5 5 5 Kelch motif Kelch_4 PF13418.6 ORY38743.1 - 3.2e-25 87.9 17.3 1.8e-06 27.9 0.0 5.8 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY38743.1 - 1.2e-23 82.1 14.7 0.00057 19.8 0.2 6.0 5 2 0 5 5 5 5 Kelch motif RAG2 PF03089.14 ORY38743.1 - 0.0048 15.9 0.2 3.2 6.6 0.0 3.8 4 1 0 4 4 4 1 Recombination activating protein 2 Sod_Fe_C PF02777.18 ORY38925.1 - 2.7e-10 40.3 0.0 1.2e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORY38925.1 - 0.046 14.2 0.0 0.071 13.6 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Proteasome PF00227.26 ORY38927.1 - 1.9e-58 197.1 0.2 2.5e-58 196.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY38927.1 - 2.1e-13 49.6 0.1 4.6e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF4010 PF13194.6 ORY38928.1 - 0.18 11.4 8.1 0.25 11.0 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) H_PPase PF03030.16 ORY38929.1 - 0.045 12.4 1.7 0.64 8.6 1.7 2.3 1 1 0 1 1 1 0 Inorganic H+ pyrophosphatase TctB PF07331.11 ORY38929.1 - 0.078 13.3 12.8 1.4 9.2 13.0 2.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2569 PF10754.9 ORY38929.1 - 0.68 10.4 5.4 0.71 10.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF4079 PF13301.6 ORY38929.1 - 2.1 8.5 6.9 0.3 11.3 2.8 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) DUF4282 PF14110.6 ORY38929.1 - 7.8 7.3 12.3 2.6 8.8 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) CbtB PF09489.10 ORY38929.1 - 7.8 6.7 5.9 16 5.7 0.1 3.3 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Ribonucleas_3_3 PF14622.6 ORY39202.1 - 0.077 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease-III-like GILT PF03227.16 ORY39203.1 - 1.1e-15 57.8 0.6 1.7e-15 57.2 0.1 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) BSD PF03909.17 ORY39204.1 - 3.5e-07 30.1 0.0 8.9e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 BSD domain Baculo_PEP_C PF04513.12 ORY39204.1 - 0.00089 19.3 3.5 0.38 10.8 1.2 2.6 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 ORY39204.1 - 0.002 18.1 11.6 0.61 9.9 0.3 3.4 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain FliD_C PF07195.12 ORY39204.1 - 0.0038 16.7 1.2 0.26 10.7 0.2 2.2 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus DUF3348 PF11828.8 ORY39204.1 - 0.012 15.3 2.6 0.015 15.0 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) ApoA-II PF04711.13 ORY39204.1 - 0.14 12.3 0.3 2.8 8.2 0.0 3.1 3 1 1 4 4 4 0 Apolipoprotein A-II (ApoA-II) DUF4618 PF15397.6 ORY39204.1 - 0.27 10.6 2.5 4.8 6.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) PP2C PF00481.21 ORY39205.1 - 5.1e-65 219.7 0.1 9.3e-49 166.4 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C ADH_zinc_N PF00107.26 ORY39256.1 - 6.8e-24 84.3 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY39256.1 - 6.9e-08 32.2 0.1 0.0043 16.6 0.1 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY39256.1 - 1.7e-06 29.1 0.0 5.3e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY39256.1 - 2e-06 27.3 0.1 3e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ORY39256.1 - 0.0041 16.7 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 ORY39256.1 - 0.0093 16.6 0.0 0.016 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY39256.1 - 0.056 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.19 ORY39256.1 - 0.12 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MDM10 PF12519.8 ORY39257.1 - 1.7e-84 284.4 0.0 5.6e-82 276.1 0.0 2.2 1 1 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 ORY39257.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic porin BCDHK_Adom3 PF10436.9 ORY39259.1 - 5.5e-40 136.8 0.0 8.1e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY39259.1 - 0.00023 21.6 0.0 0.091 13.3 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 ORY39259.1 - 0.00098 19.1 0.0 0.0052 16.7 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ORY39259.1 - 0.038 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TauD PF02668.16 ORY39260.1 - 1.2e-47 163.0 0.1 1.6e-47 162.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_trans_2_3 PF13632.6 ORY39261.1 - 4.9e-25 88.6 3.5 4.9e-25 88.6 3.5 3.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Acyl_transf_3 PF01757.22 ORY39261.1 - 1.1e-13 51.0 30.7 1.1e-13 51.0 30.7 2.8 3 0 0 3 3 3 1 Acyltransferase family Glyco_tranf_2_3 PF13641.6 ORY39261.1 - 1e-12 48.5 0.0 2.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 p450 PF00067.22 ORY39481.1 - 0.009 14.8 0.0 0.0097 14.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 G_glu_transpept PF01019.21 ORY39482.1 - 1.5e-150 502.4 0.6 1.8e-150 502.2 0.6 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HSP70 PF00012.20 ORY39483.1 - 1e-38 132.9 0.0 1.7e-19 69.5 0.0 2.0 1 1 1 2 2 2 2 Hsp70 protein PI-PLC-X PF00388.19 ORY39486.1 - 2.5e-61 205.5 0.0 4.5e-61 204.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 ORY39486.1 - 5.4e-42 142.8 0.0 1.1e-41 141.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ORY39486.1 - 2e-06 28.0 0.0 8.4e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 C2 domain GDPD PF03009.17 ORY39486.1 - 4.5e-05 23.3 0.0 9.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family EF-hand_like PF09279.11 ORY39486.1 - 0.00016 22.1 0.0 0.00038 20.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like MFS_1 PF07690.16 ORY39487.1 - 4.3e-14 52.2 29.6 4.3e-14 52.2 29.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxidored_q3 PF00499.20 ORY39487.1 - 0.04 13.7 4.8 0.069 12.9 3.8 2.0 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 RSN1_7TM PF02714.15 ORY39668.1 - 1.4e-79 267.3 24.3 2.6e-79 266.4 24.3 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY39668.1 - 2.2e-40 137.9 2.6 2.2e-40 137.9 2.6 2.7 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY39668.1 - 1.7e-35 122.8 0.0 2.5e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter A_deaminase PF00962.22 ORY39669.1 - 3.3e-26 92.4 0.0 4.6e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase RSN1_7TM PF02714.15 ORY39670.1 - 1.8e-79 267.0 24.3 3.2e-79 266.1 24.3 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY39670.1 - 2.6e-40 137.7 2.6 2.6e-40 137.7 2.6 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY39670.1 - 1.9e-35 122.7 0.0 3e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORY39670.1 - 4.5e-15 55.6 0.0 1.3e-14 54.2 0.0 1.7 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter A_deaminase PF00962.22 ORY39671.1 - 1.3e-122 409.2 0.1 1.8e-122 408.8 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase OAM_alpha PF16552.5 ORY39671.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit p450 PF00067.22 ORY39731.1 - 7.3e-31 107.4 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 UQ_con PF00179.26 ORY39732.1 - 2.2e-14 53.3 0.0 3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY39732.1 - 0.086 13.1 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain CDC45 PF02724.14 ORY39733.1 - 0.0016 16.9 7.8 0.0021 16.4 7.8 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 ORY39733.1 - 0.0032 17.6 8.3 0.0056 16.8 8.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein CENP-B_dimeris PF09026.10 ORY39733.1 - 0.019 15.3 19.6 0.044 14.2 19.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 ORY39733.1 - 0.068 12.5 11.9 0.11 11.8 11.9 1.2 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 ORY39733.1 - 0.15 10.1 27.5 0.25 9.4 27.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 ORY39733.1 - 0.29 11.0 14.9 0.47 10.3 14.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RPN2_C PF18004.1 ORY39733.1 - 0.39 10.6 5.7 0.77 9.7 5.7 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SDA1 PF05285.12 ORY39733.1 - 0.48 9.8 17.9 0.73 9.2 17.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ORY39733.1 - 0.51 8.5 19.4 0.74 8.0 19.4 1.1 1 0 0 1 1 1 0 Nop14-like family Drc1-Sld2 PF11719.8 ORY39733.1 - 0.52 9.8 9.4 1 8.8 9.4 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Merozoite_SPAM PF07133.11 ORY39733.1 - 0.53 10.3 24.2 0.81 9.6 24.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) GCIP PF13324.6 ORY39733.1 - 0.6 9.7 6.1 0.9 9.1 6.1 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting TFB6 PF17110.5 ORY39733.1 - 0.81 9.4 7.3 1.5 8.6 7.3 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop16 PF09420.10 ORY39733.1 - 1.1 9.2 5.4 2.2 8.2 5.4 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Cwf_Cwc_15 PF04889.12 ORY39733.1 - 1.5 8.5 15.1 2.7 7.7 15.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mpp10 PF04006.12 ORY39733.1 - 3.4 6.0 18.9 4.8 5.5 18.9 1.1 1 0 0 1 1 1 0 Mpp10 protein RXT2_N PF08595.11 ORY39733.1 - 6.4 6.8 11.1 14 5.7 11.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 ORY39733.1 - 9.6 5.4 22.2 17 4.6 22.2 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 ORY39738.1 - 1.1e-47 162.7 0.0 1.6e-47 162.1 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39738.1 - 8.6e-25 87.5 0.0 1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY39738.1 - 7.2e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY39738.1 - 0.00085 18.7 0.0 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY39738.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Fasciclin PF02469.22 ORY39744.1 - 1.8e-20 73.5 0.0 1.3e-09 38.4 0.0 2.6 2 1 0 2 2 2 2 Fasciclin domain Vps51 PF08700.11 ORY40008.1 - 1.7e-23 82.5 0.3 2.6e-23 81.9 0.3 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 ORY40008.1 - 5.8e-05 23.3 0.7 8.6e-05 22.7 0.7 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 ORY40008.1 - 0.00035 19.4 0.7 0.00044 19.1 0.7 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.12 ORY40008.1 - 0.0034 17.9 1.1 0.0056 17.2 1.1 1.3 1 0 0 1 1 1 1 FlgN protein Allexi_40kDa PF05549.11 ORY40008.1 - 0.014 15.0 1.3 0.02 14.5 1.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spc7 PF08317.11 ORY40008.1 - 0.11 11.3 0.3 0.15 10.9 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein MSP1_C PF07462.11 ORY40008.1 - 0.2 10.3 0.2 0.29 9.8 0.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus GMC_oxred_N PF00732.19 ORY40009.1 - 2.7e-64 217.4 0.0 3.9e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY40009.1 - 1.2e-32 113.4 0.0 2.5e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY40009.1 - 6.2e-07 28.8 0.1 9e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY40009.1 - 1.1e-05 24.7 0.3 0.017 14.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY40009.1 - 1.5e-05 24.7 1.5 0.00011 22.0 1.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY40009.1 - 5.2e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORY40009.1 - 0.00019 21.6 0.1 0.0005 20.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY40009.1 - 0.0002 20.7 0.0 0.00059 19.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY40009.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 ORY40009.1 - 0.014 14.1 0.2 0.023 13.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 ORY40009.1 - 0.041 13.2 0.9 0.067 12.5 0.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY40009.1 - 0.071 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 ORY40009.1 - 0.086 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 ORY40009.1 - 0.16 11.9 0.1 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding RhoGAP PF00620.27 ORY40010.1 - 5.1e-47 159.5 0.0 2.3e-46 157.3 0.0 2.2 3 0 0 3 3 3 1 RhoGAP domain RasGEF_N PF00618.20 ORY40010.1 - 6.5e-13 48.8 0.0 2.9e-12 46.7 0.0 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 ORY40010.1 - 1.4e-12 48.1 0.0 7.2e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain PH PF00169.29 ORY40010.1 - 7.4e-05 23.2 0.0 0.00036 21.0 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 ORY40010.1 - 0.00019 21.8 0.0 0.0026 18.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Ribosomal_L29e PF01779.17 ORY40011.1 - 2.6e-23 82.0 10.6 3.5e-23 81.6 10.6 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family SNARE_assoc PF09335.11 ORY40012.1 - 6.1e-13 49.3 13.1 1.5e-12 48.1 8.8 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein Syntaxin-18_N PF10496.9 ORY40013.1 - 4.6e-10 39.6 2.3 1.4e-09 38.1 0.0 2.8 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 ORY40013.1 - 0.0061 16.5 1.7 0.013 15.5 0.0 2.4 3 0 0 3 3 3 1 SNARE domain SelK_SelG PF10961.8 ORY40013.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.7 1 0 0 1 1 1 0 Selenoprotein SelK_SelG CCDC-167 PF15188.6 ORY40013.1 - 0.18 12.2 3.6 0.31 11.4 0.9 2.8 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 APG6_N PF17675.1 ORY40013.1 - 1.6 9.3 10.9 1.1 9.7 4.8 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region Tau95 PF09734.9 ORY40014.1 - 3.2e-36 125.2 1.1 4.2e-36 124.8 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 ORY40014.1 - 6e-27 94.4 0.0 6e-27 94.4 0.0 2.1 2 0 0 2 2 2 1 Tau95 Triple barrel domain DUF2095 PF09868.9 ORY40014.1 - 0.033 14.2 0.0 0.87 9.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) NMT1 PF09084.11 ORY40072.1 - 2.4e-61 207.4 0.0 3.4e-61 206.9 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ORY40072.1 - 0.00039 20.2 0.0 0.02 14.6 0.0 2.8 3 0 0 3 3 3 1 NMT1-like family DUF2844 PF11005.8 ORY40072.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2844) VanZ PF04892.12 ORY40074.1 - 9.5e-06 26.3 0.4 1.8e-05 25.4 0.4 1.4 1 1 0 1 1 1 1 VanZ like family APG9 PF04109.16 ORY40075.1 - 2.5e-174 580.8 0.0 8.1e-100 335.1 0.0 2.0 1 1 1 2 2 2 2 Autophagy protein Apg9 Myb_DNA-bind_4 PF13837.6 ORY40076.1 - 0.023 15.1 0.5 0.061 13.7 0.0 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY40076.1 - 0.03 14.5 0.1 6.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY40076.1 - 0.034 14.4 0.1 4.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain DGF-1_C PF11040.8 ORY40076.1 - 0.77 9.8 3.9 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Myb_DNA-bind_6 PF13921.6 ORY40079.1 - 0.0091 16.2 0.0 0.07 13.4 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY40079.1 - 0.11 12.6 0.0 2.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY40080.1 - 0.42 10.6 5.0 0.49 10.3 2.5 2.1 2 0 0 2 2 2 0 Myb DNA-binding like DSS1_SEM1 PF05160.13 ORY40561.1 - 1.3e-19 70.0 9.7 2.3e-19 69.2 9.7 1.4 1 0 0 1 1 1 1 DSS1/SEM1 family Peptidase_C15 PF01470.17 ORY40562.1 - 2.8e-11 44.0 0.0 0.00014 22.1 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase F-box PF00646.33 ORY40563.1 - 1.7e-06 27.7 3.3 2e-05 24.3 0.1 3.5 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 ORY40563.1 - 3.7e-06 26.7 0.5 3.7e-06 26.7 0.5 3.0 4 0 0 4 4 4 1 F-box-like p450 PF00067.22 ORY40564.1 - 1.4e-51 175.7 0.0 2.2e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1779 PF08680.10 ORY40564.1 - 3.7 7.7 6.1 1.7 8.8 3.4 1.8 2 0 0 2 2 2 0 TATA-box binding RNA_pol_A_bac PF01000.26 ORY40567.1 - 2.2e-28 98.9 0.0 3.2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORY40567.1 - 1.5e-17 62.8 0.0 2.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sec3_C_2 PF15278.6 ORY40567.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DUF4636 PF15468.6 ORY40568.1 - 0.0039 16.9 3.8 0.0059 16.4 3.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4636) FmiP_Thoc5 PF09766.9 ORY40568.1 - 0.035 13.4 0.4 0.055 12.8 0.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 Cwf_Cwc_15 PF04889.12 ORY40568.1 - 0.91 9.2 7.1 1.3 8.7 7.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LRR_1 PF00560.33 ORY40568.1 - 8.4 7.4 6.6 1.2e+02 3.9 0.3 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat DNA_ligase_A_C PF04679.15 ORY40570.1 - 0.086 13.4 0.3 9 7.0 0.0 2.4 1 1 1 2 2 2 0 ATP dependent DNA ligase C terminal region Exonuc_VII_L PF02601.15 ORY40570.1 - 0.49 9.9 8.8 0.84 9.1 8.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit MFS_1 PF07690.16 ORY40624.1 - 4e-11 42.4 30.5 4.6e-11 42.2 29.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY40624.1 - 1.2e-09 38.1 0.4 1.2e-09 38.1 0.4 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Thiolase_N PF00108.23 ORY40625.1 - 3.1e-67 226.7 1.6 4.4e-67 226.2 1.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY40625.1 - 2.6e-42 143.3 0.2 8.5e-42 141.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY40625.1 - 0.0036 16.9 0.2 0.0077 15.8 0.2 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MFS_1 PF07690.16 ORY40626.1 - 1e-30 106.9 41.5 2.9e-24 85.7 32.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IncD PF17628.2 ORY40626.1 - 0.76 9.6 3.6 0.38 10.5 0.5 2.1 2 0 0 2 2 2 0 Inclusion membrane protein D Thymidylate_kin PF02223.17 ORY40627.1 - 5.4e-44 150.1 0.0 6.2e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 ORY40627.1 - 0.075 13.3 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PPK2 PF03976.14 ORY40627.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) DNA_alkylation PF08713.11 ORY40627.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme PRK PF00485.18 ORY40627.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 ORY40627.1 - 0.21 11.0 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF3131 PF11329.8 ORY40628.1 - 0.091 11.8 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) GYF PF02213.16 ORY40630.1 - 6.4e-05 22.5 2.4 0.00013 21.6 2.0 1.7 2 0 0 2 2 2 1 GYF domain Lumazine_bd_2 PF12893.7 ORY40630.1 - 0.062 14.0 0.6 0.16 12.7 0.1 1.8 2 0 0 2 2 2 0 Putative lumazine-binding Acetyltransf_1 PF00583.25 ORY40631.1 - 8e-10 39.0 0.0 1.3e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY40631.1 - 5e-08 32.9 0.0 2e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY40631.1 - 1.3e-05 25.6 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY40631.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Pyr_redox_2 PF07992.14 ORY40632.1 - 3.3e-68 230.1 2.4 4.4e-68 229.7 2.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY40632.1 - 5.4e-35 120.0 0.4 2e-34 118.2 0.3 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY40632.1 - 2.5e-24 85.7 3.7 7.6e-21 74.5 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY40632.1 - 2.4e-15 56.6 4.8 1.8e-12 47.1 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY40632.1 - 4.4e-10 38.8 1.1 0.00061 18.6 0.4 2.9 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 ORY40632.1 - 6.9e-10 38.9 0.4 1.9e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY40632.1 - 4.1e-07 29.4 0.3 1.4e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORY40632.1 - 1.2e-06 28.7 1.4 3.2e-06 27.3 1.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORY40632.1 - 1.1e-05 24.9 0.6 0.014 14.7 0.2 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY40632.1 - 0.00013 21.2 2.7 0.00013 21.2 2.7 2.5 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 ORY40632.1 - 0.00017 20.9 0.2 0.00017 20.9 0.2 1.9 3 0 0 3 3 3 1 Thi4 family 3HCDH_N PF02737.18 ORY40632.1 - 0.00053 19.9 2.5 0.044 13.7 0.1 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY40632.1 - 0.0013 19.2 0.4 0.17 12.3 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 ORY40632.1 - 0.0019 17.4 0.1 0.0083 15.3 0.0 2.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY40632.1 - 0.0025 17.5 9.1 0.014 15.0 3.9 2.8 2 2 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY40632.1 - 0.0077 15.5 2.3 0.23 10.6 0.1 2.6 2 1 1 3 3 3 1 FAD binding domain Amino_oxidase PF01593.24 ORY40632.1 - 0.032 13.5 1.3 0.78 9.0 0.0 2.4 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 ORY40632.1 - 0.043 13.2 0.3 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ORY40632.1 - 0.072 12.1 0.5 0.53 9.3 0.3 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Sugar_tr PF00083.24 ORY40633.1 - 5.1e-88 295.9 12.7 6.4e-88 295.6 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY40633.1 - 2.5e-15 56.3 40.0 3.5e-12 45.9 9.4 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY40633.1 - 0.00019 20.0 5.7 0.07 11.5 0.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 ORY40633.1 - 0.0032 16.4 0.8 0.0032 16.4 0.8 1.7 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Peptidase_M28 PF04389.17 ORY40634.1 - 1e-36 126.5 0.0 2.9e-36 125.0 0.0 1.8 2 1 0 2 2 2 1 Peptidase family M28 SNF2_N PF00176.23 ORY40897.1 - 4.1e-59 200.1 2.0 9.1e-59 198.9 1.1 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY40897.1 - 8.3e-14 51.9 0.1 1.4e-12 47.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY40897.1 - 2e-08 34.4 1.9 2.6e-08 34.0 0.2 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 ORY40897.1 - 2e-08 34.0 4.1 4.2e-08 33.0 4.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY40897.1 - 1.2e-07 32.0 4.5 3.1e-07 30.6 4.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY40897.1 - 3.6e-07 30.1 0.7 8.6e-07 28.9 0.3 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY40897.1 - 7.9e-07 28.8 1.6 2.1e-06 27.5 1.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY40897.1 - 3.3e-05 23.6 1.6 3.3e-05 23.6 1.6 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY40897.1 - 0.00027 20.7 8.2 0.003 17.4 8.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY40897.1 - 0.0072 16.1 3.2 0.018 14.8 3.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 ORY40897.1 - 0.0081 15.9 5.5 0.029 14.2 5.5 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain AAA_34 PF13872.6 ORY40897.1 - 0.034 13.0 0.1 0.073 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Prok-RING_4 PF14447.6 ORY40897.1 - 0.1 12.5 10.4 0.94 9.4 5.5 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY40897.1 - 0.21 11.8 5.8 0.061 13.5 1.5 2.4 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING Fer2 PF00111.27 ORY40897.1 - 0.22 11.5 2.8 0.62 10.1 2.8 1.8 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-rbx1 PF12678.7 ORY40897.1 - 0.33 11.3 3.8 1.2 9.5 3.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY40897.1 - 0.83 9.6 4.7 1.2 9.0 0.7 2.5 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 ORY40897.1 - 0.95 9.6 5.4 6.3 6.9 5.4 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.7 ORY40897.1 - 1.2 9.2 4.4 7.3 6.7 4.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon Senescence_reg PF04520.13 ORY40897.1 - 6 7.7 8.8 0.31 11.9 1.4 2.5 3 0 0 3 3 2 0 Senescence regulator GMC_oxred_C PF05199.13 ORY40899.1 - 1e-14 55.3 0.4 8.7e-14 52.3 0.1 2.5 2 2 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 ORY40899.1 - 4e-07 29.7 0.0 1.1e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY40899.1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pep3_Vps18 PF05131.14 ORY40901.1 - 1.5e-46 157.9 0.0 2.7e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 ORY40901.1 - 2.6e-07 30.6 9.3 5.6e-06 26.3 1.1 2.6 2 1 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 ORY40901.1 - 0.0002 21.2 1.2 0.0004 20.3 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.9 ORY40901.1 - 0.00036 20.9 0.0 0.0017 18.8 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.6 ORY40901.1 - 0.0066 16.3 1.6 0.015 15.1 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY40901.1 - 0.0079 15.8 0.3 0.0079 15.8 0.3 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 ORY40901.1 - 0.0086 16.1 1.5 0.0086 16.1 1.5 1.7 2 0 0 2 2 1 1 Zinc-finger zf-RING_2 PF13639.6 ORY40901.1 - 0.013 15.8 1.1 0.034 14.5 1.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_11 PF17123.5 ORY40901.1 - 0.016 15.0 1.5 0.035 13.8 1.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY40901.1 - 0.027 14.5 0.1 0.063 13.3 0.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF3363 PF11843.8 ORY40901.1 - 0.074 12.0 0.4 0.14 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) DUF2175 PF09943.9 ORY40901.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) RNase_P_pop3 PF08228.11 ORY40902.1 - 6.6e-10 39.3 0.2 0.01 15.9 0.0 3.5 4 0 0 4 4 4 3 RNase P subunit Pop3 Peptidase_C2 PF00648.21 ORY40903.1 - 4.6e-28 98.1 0.0 8e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 ORY40903.1 - 1.4e-06 28.7 0.1 0.00026 21.3 0.0 3.3 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.18 ORY40903.1 - 4.8e-05 23.3 1.3 7.6e-05 22.7 1.3 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain ubiquitin PF00240.23 ORY40904.1 - 1.4e-22 79.2 0.8 1.6e-22 79.1 0.8 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY40904.1 - 1.4e-11 44.1 0.1 1.5e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY40904.1 - 0.0073 16.7 0.5 0.02 15.3 0.5 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY40904.1 - 0.015 15.6 0.3 0.016 15.5 0.3 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY40904.1 - 0.02 14.8 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain FERM_f0 PF16511.5 ORY40904.1 - 0.16 12.3 0.4 1.2 9.4 0.4 1.9 1 1 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM Nucleo_P87 PF07267.11 ORY41110.1 - 0.41 9.4 1.3 0.55 9.0 1.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2828 PF11443.8 ORY41110.1 - 0.75 7.8 5.2 1 7.4 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NPR3 PF03666.13 ORY41110.1 - 0.96 8.2 4.4 1.4 7.6 4.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 ORY41110.1 - 1.7 7.4 3.3 2.6 6.7 3.3 1.2 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 ORY41110.1 - 3.9 6.8 9.5 6.1 6.2 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2956 PF11169.8 ORY41110.1 - 9.5 6.5 11.8 3.2 8.0 8.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Lipase_GDSL_2 PF13472.6 ORY41111.1 - 6.4e-06 26.7 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PC-Esterase PF13839.6 ORY41111.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Adap_comp_sub PF00928.21 ORY41112.1 - 2.5e-91 305.7 0.1 6.4e-91 304.4 0.0 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY41112.1 - 1.3e-08 34.9 0.3 2.4e-08 34.0 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 ORY41112.1 - 0.0047 16.4 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF5596 PF18082.1 ORY41114.1 - 0.096 12.5 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) TPR_9 PF13371.6 ORY41114.1 - 0.18 12.0 3.5 0.77 10.0 3.5 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat JAB PF01398.21 ORY41115.1 - 1.7e-30 105.4 0.0 3.2e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 ORY41115.1 - 2.6e-26 92.4 0.5 5.9e-26 91.2 0.3 1.7 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 ORY41115.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 ORY41115.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Mlh1_C PF16413.5 ORY41116.1 - 1.7e-88 296.5 1.0 6.2e-88 294.7 0.2 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 ORY41116.1 - 6.1e-30 103.3 0.0 1.1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY41116.1 - 1.7e-11 44.1 0.0 3.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY41116.1 - 1.6e-07 31.8 0.0 4.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase F-box-like PF12937.7 ORY41180.1 - 0.00041 20.2 0.1 0.00072 19.4 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY41180.1 - 0.042 13.7 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box PI3Ka PF00613.20 ORY41181.1 - 1.5e-51 174.4 0.0 2.6e-51 173.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 ORY41181.1 - 3.4e-45 154.8 0.0 3.5e-30 105.7 0.0 2.7 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 ORY41181.1 - 1.1e-29 103.1 0.0 2.2e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 ORY41181.1 - 0.0027 18.0 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Mating_N PF12731.7 ORY41181.1 - 0.037 14.1 0.3 0.92 9.6 0.0 2.7 3 0 0 3 3 3 0 Mating-type protein beta 1 DUF4078 PF13300.6 ORY41182.1 - 1.2e-17 64.0 15.9 1.2e-17 64.0 15.9 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) MerR-DNA-bind PF09278.11 ORY41182.1 - 0.19 12.3 6.6 5.1 7.7 0.0 3.8 4 0 0 4 4 4 0 MerR, DNA binding ThiS PF02597.20 ORY41183.1 - 0.01 16.5 0.0 0.014 16.0 0.0 1.4 1 1 0 1 1 1 0 ThiS family Methyltransf_31 PF13847.6 ORY41184.1 - 2.4e-14 53.4 0.0 3.7e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY41184.1 - 3.3e-07 30.9 0.0 1.6e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY41184.1 - 9.1e-06 25.6 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY41184.1 - 3.1e-05 24.6 0.0 6.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY41184.1 - 0.00011 22.7 0.0 0.00053 20.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY41184.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ORY41184.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 ORY41184.1 - 0.019 14.6 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW tRNA_U5-meth_tr PF05958.11 ORY41184.1 - 0.15 11.0 0.0 0.21 10.6 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase AdoMet_MTase PF07757.13 ORY41184.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase ADH_N PF08240.12 ORY41185.1 - 4.1e-12 45.9 4.9 5.7e-12 45.5 4.9 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain F-box PF00646.33 ORY41186.1 - 7.6e-05 22.5 1.8 0.00018 21.3 1.8 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY41186.1 - 0.0026 17.6 0.9 0.0059 16.5 0.9 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY41186.1 - 0.089 12.7 2.4 0.32 10.9 0.1 2.5 3 0 0 3 3 3 0 F-box ADH_N PF08240.12 ORY41187.1 - 2.7e-21 75.5 11.0 6.8e-21 74.2 11.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY41187.1 - 0.00029 20.8 0.0 0.00057 19.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MIS13 PF08202.11 ORY41188.1 - 2.6e-16 59.8 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Rtf2 PF04641.12 ORY41189.1 - 2.7e-61 207.2 0.3 3.3e-61 206.9 0.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 ORY41189.1 - 0.00062 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 ORY41189.1 - 0.00073 19.3 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit CLP_protease PF00574.23 ORY41190.1 - 3e-64 216.2 0.0 3.8e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 Clp protease G-alpha PF00503.20 ORY41191.1 - 1.1e-104 350.4 0.7 1.3e-104 350.2 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY41191.1 - 3.3e-13 49.5 0.6 1.8e-08 34.0 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY41191.1 - 0.00088 18.7 3.2 0.033 13.6 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY41191.1 - 0.0067 16.6 0.1 1.5 9.1 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY41191.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY41191.1 - 0.14 12.3 0.0 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PRP21_like_P PF12230.8 ORY41192.1 - 1.4e-42 146.1 8.3 2e-42 145.5 8.3 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 ORY41192.1 - 1.8e-31 107.9 3.6 2.7e-15 56.1 0.3 2.5 2 0 0 2 2 2 2 Surp module DUF2857 PF11198.8 ORY41192.1 - 2.9 7.6 6.1 1.2 8.9 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Exo_endo_phos PF03372.23 ORY41444.1 - 1.3e-09 37.9 0.0 3.2e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 ORY41444.1 - 0.067 14.1 2.7 17 6.5 0.1 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat Zn_clus PF00172.18 ORY41445.1 - 0.031 14.4 6.0 0.048 13.8 6.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Syja_N PF02383.18 ORY41446.1 - 3.9e-55 187.4 0.0 5.6e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain GFA PF04828.14 ORY41447.1 - 5.1e-17 62.0 0.0 7.9e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 ORY41447.1 - 0.28 11.1 0.0 0.28 11.1 0.0 2.4 2 1 0 2 2 2 0 Nudix N-terminal ADD_DNMT3 PF17980.1 ORY41447.1 - 3.9 7.5 5.6 1.3 9.1 2.4 1.9 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 Glyco_hydro_101 PF12905.7 ORY41448.1 - 0.076 12.4 0.7 0.11 11.9 0.7 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase Sec23_helical PF04815.15 ORY41448.1 - 0.083 12.7 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 helical domain Gpi1 PF05024.15 ORY41449.1 - 5.3e-61 206.0 8.5 9.4e-61 205.2 8.5 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DUF2070 PF09843.9 ORY41449.1 - 4 5.6 7.4 5.7 5.1 7.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CMS1 PF14617.6 ORY41450.1 - 3.4e-64 216.6 0.9 4.1e-64 216.3 0.9 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 ORY41450.1 - 2.1e-05 24.4 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA_polI_A34 PF08208.11 ORY41450.1 - 0.13 12.3 9.4 0.24 11.5 9.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N PF04086.13 ORY41450.1 - 5.5 6.8 10.3 8.3 6.2 10.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal L31 PF09784.9 ORY41451.1 - 5.5e-42 142.3 0.2 6.2e-42 142.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 E1-E2_ATPase PF00122.20 ORY41452.1 - 4.1e-53 179.6 10.4 5.6e-52 175.9 6.3 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY41452.1 - 1.5e-47 161.7 6.7 1.5e-47 161.7 6.7 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY41452.1 - 4e-22 79.6 1.3 2.1e-21 77.2 1.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY41452.1 - 2.6e-21 75.5 0.0 6.1e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY41452.1 - 2.1e-20 72.1 0.1 5.4e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY41452.1 - 1.5e-06 28.2 0.7 0.00014 21.7 0.4 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY41452.1 - 9e-06 26.2 0.0 2.3e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 ORY41452.1 - 0.67 10.3 4.5 6.4 7.1 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) Aminotran_3 PF00202.21 ORY41453.1 - 3.6e-83 279.5 0.0 4.3e-83 279.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY41453.1 - 0.019 14.1 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Sugar_tr PF00083.24 ORY41454.1 - 1.7e-86 290.9 15.6 2.1e-86 290.6 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY41454.1 - 1.7e-23 83.1 48.3 4e-19 68.8 20.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3135 PF11333.8 ORY41454.1 - 0.2 11.9 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Ctr PF04145.15 ORY41454.1 - 0.41 11.3 0.1 0.41 11.3 0.1 2.1 2 0 0 2 2 2 0 Ctr copper transporter family DUF455 PF04305.14 ORY41455.1 - 1.5e-92 309.7 0.0 1.7e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 ORY41455.1 - 0.01 15.7 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain RCR PF12273.8 ORY41747.1 - 0.015 15.9 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Syndecan PF01034.20 ORY41747.1 - 0.14 12.1 1.5 0.19 11.6 1.5 1.2 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.6 ORY41747.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 Amnionless MRP-L20 PF12824.7 ORY41748.1 - 7.7e-22 78.2 5.7 1e-21 77.8 5.7 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 ORY41748.1 - 0.0022 18.0 0.2 0.044 13.8 0.0 2.2 1 1 1 2 2 2 1 Neugrin DUF5349 PF17298.2 ORY41748.1 - 0.61 9.8 5.5 0.68 9.6 5.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) CCDC-167 PF15188.6 ORY41749.1 - 0.87 10.0 19.1 0.21 12.0 0.5 3.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Abhydrolase_2 PF02230.16 ORY41750.1 - 2.8e-55 187.5 0.0 3.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY41750.1 - 1.5e-07 30.9 0.1 0.02 14.1 0.0 3.1 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY41750.1 - 3.7e-07 31.0 0.1 4.7e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY41750.1 - 4.2e-05 23.2 0.0 7.8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 ORY41750.1 - 7.5e-05 22.5 0.0 0.00014 21.6 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 ORY41750.1 - 0.0021 18.0 0.0 0.4 10.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 ORY41750.1 - 0.0038 16.9 0.1 0.0056 16.3 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Cutinase PF01083.22 ORY41750.1 - 0.054 13.5 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase LIP PF03583.14 ORY41750.1 - 0.11 11.8 0.0 1.6 8.0 0.0 2.1 1 1 1 2 2 2 0 Secretory lipase RGS PF00615.19 ORY41751.1 - 2.5e-12 47.1 0.0 2.9e-07 30.8 0.0 2.4 2 1 0 2 2 2 2 Regulator of G protein signaling domain DUF4199 PF13858.6 ORY41751.1 - 0.024 15.0 6.6 0.039 14.4 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ribosomal_S24e PF01282.19 ORY41752.1 - 2.9e-34 116.9 0.0 4.6e-34 116.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e L51_S25_CI-B8 PF05047.16 ORY41753.1 - 1.5e-10 40.9 0.0 1.9e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RE_XcyI PF09571.10 ORY41753.1 - 0.0071 15.6 0.0 0.0074 15.6 0.0 1.0 1 0 0 1 1 1 1 XcyI restriction endonuclease zf-MYND PF01753.18 ORY41755.1 - 1.9e-09 37.4 11.7 3.5e-09 36.6 11.7 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY41755.1 - 0.018 15.4 9.4 0.041 14.2 9.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Rhodanese_C PF12368.8 ORY41755.1 - 0.043 14.2 4.4 0.073 13.5 4.4 1.4 1 0 0 1 1 1 0 Rhodanase C-terminal Phage_min_cap2 PF06152.11 ORY41755.1 - 0.052 12.4 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 zf-HIT PF04438.16 ORY41755.1 - 0.52 10.2 9.6 1 9.3 9.6 1.5 1 0 0 1 1 1 0 HIT zinc finger Nnf1 PF03980.14 ORY41756.1 - 0.00015 22.1 1.1 0.00075 19.8 0.2 2.4 3 0 0 3 3 3 1 Nnf1 Peptidase_C98 PF15499.6 ORY41756.1 - 0.087 12.3 0.1 5.4 6.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase UPF0122 PF04297.14 ORY41756.1 - 0.17 12.1 0.7 0.34 11.2 0.3 1.7 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like Gcw_chp PF09694.10 ORY41757.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (Gcw_chp) Med8 PF10232.9 ORY41758.1 - 0.054 13.1 17.2 1.7 8.2 17.2 2.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 SLX9 PF15341.6 ORY41758.1 - 1.7 9.0 8.5 0.26 11.7 3.2 2.2 2 2 0 2 2 2 0 Ribosome biogenesis protein SLX9 GATase PF00117.28 ORY41759.1 - 1.2e-10 41.5 0.0 2.4e-10 40.5 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Malate_synthase PF01274.22 ORY41760.1 - 4e-114 381.8 0.0 4.4e-114 381.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase LRR_4 PF12799.7 ORY41816.1 - 0.012 16.1 2.7 8.7 6.9 0.3 4.3 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) NAD_binding_6 PF08030.12 ORY41817.1 - 1.2e-11 45.0 0.0 1.1e-07 32.1 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY41817.1 - 2.3e-11 43.9 4.6 2.3e-11 43.9 4.6 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY41817.1 - 6.6e-07 29.4 0.0 3.6e-06 27.0 0.0 2.1 2 1 0 2 2 2 1 FAD-binding domain TMEM18 PF14770.6 ORY41817.1 - 0.18 11.8 0.1 0.51 10.3 0.1 1.7 1 0 0 1 1 1 0 Transmembrane protein 18 zf-NOSIP PF15906.5 ORY41818.1 - 1.8e-11 44.0 0.1 4.5e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 ORY41818.1 - 0.00032 20.7 1.4 0.00032 20.7 1.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.12 ORY41818.1 - 0.00063 19.2 4.9 0.00063 19.2 4.9 2.6 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.6 ORY41818.1 - 0.00086 19.6 25.1 0.081 13.3 1.5 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 ORY41818.1 - 0.0024 17.7 1.9 0.0024 17.7 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY41818.1 - 0.0065 16.3 2.1 0.0065 16.3 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY41818.1 - 0.051 13.5 24.3 0.07 13.1 13.0 2.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY41818.1 - 0.055 13.6 1.8 0.055 13.6 1.8 2.7 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF4746 PF15928.5 ORY41818.1 - 0.086 12.2 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) zf-C3HC4_3 PF13920.6 ORY41818.1 - 0.09 12.7 27.4 0.61 10.0 2.0 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3029 PF11230.8 ORY41818.1 - 0.19 10.1 0.0 0.28 9.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) Prok-RING_4 PF14447.6 ORY41818.1 - 1.6 8.6 25.1 5.4 7.0 2.0 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 MFS_1 PF07690.16 ORY41819.1 - 5.2e-23 81.5 45.0 5.4e-11 42.0 18.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY41819.1 - 0.0012 17.8 10.8 0.0053 15.7 1.1 2.2 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 ORY41819.1 - 0.14 10.4 8.6 0.046 12.0 0.9 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family CFEM PF05730.11 ORY41821.1 - 4.5e-10 39.5 13.8 1.1e-09 38.3 13.8 1.7 1 0 0 1 1 1 1 CFEM domain FMO-like PF00743.19 ORY41822.1 - 6.7e-14 51.2 0.3 6.3e-13 48.0 0.2 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORY41822.1 - 1.5e-12 47.3 0.1 1.2e-10 41.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY41822.1 - 1.1e-09 38.3 0.0 2.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY41822.1 - 1.5e-08 34.2 0.0 0.0012 18.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY41822.1 - 3.1e-08 33.3 0.0 6.7e-07 28.8 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY41822.1 - 1.8e-05 24.5 0.3 0.019 14.6 0.1 3.1 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY41822.1 - 0.00025 21.1 0.1 2 8.4 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 ORY41822.1 - 0.0019 17.5 0.1 0.044 13.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 ORY41822.1 - 0.023 13.8 0.1 2.5 7.1 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY41822.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain PK PF00224.21 ORY41825.1 - 5.9e-164 545.0 0.9 7.8e-164 544.6 0.9 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORY41825.1 - 3.4e-37 127.2 0.0 8.6e-37 125.9 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORY41825.1 - 0.0023 17.1 0.2 0.0072 15.5 0.2 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 ORY41825.1 - 0.01 14.9 0.0 0.1 11.5 0.0 2.2 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain FlpD PF02662.16 ORY41825.1 - 0.13 12.3 0.6 16 5.5 0.0 2.6 1 1 1 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit Cellulase PF00150.18 ORY41825.1 - 0.13 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Myc_N PF01056.18 ORY41826.1 - 1.3 8.8 9.5 0.6 10.0 3.5 2.1 2 0 0 2 2 2 0 Myc amino-terminal region Kei1 PF08552.11 ORY41827.1 - 5.3e-52 176.5 1.5 8.5e-52 175.8 1.5 1.3 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 tRNA_int_endo PF01974.17 ORY41829.1 - 1.3e-12 47.6 0.0 3.1e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain SAC3_GANP PF03399.16 ORY42130.1 - 0.024 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 SAC3/GANP family TRP PF06011.12 ORY42131.1 - 1.9e-76 257.5 25.2 3.8e-76 256.5 25.2 1.4 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 ORY42131.1 - 4.6e-24 85.4 0.1 1.1e-23 84.2 0.0 1.7 2 0 0 2 2 2 1 ML-like domain DUF4834 PF16118.5 ORY42131.1 - 0.5 11.4 8.8 6.8 7.7 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 ORY42131.1 - 0.63 10.4 6.9 0.71 10.2 0.4 2.9 2 0 0 2 2 2 0 Orf78 (ac78) CPSase_sm_chain PF00988.22 ORY42132.1 - 9.8e-44 148.3 0.0 1.5e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORY42132.1 - 1.2e-37 129.6 0.0 1.6e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY42132.1 - 5.7e-09 36.0 0.1 2e-07 31.0 0.1 2.8 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 ORY42132.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family DNA_pol_B_exo2 PF10108.9 ORY42132.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB W2 PF02020.18 ORY42133.1 - 5.2e-18 65.0 1.6 1.3e-17 63.6 0.1 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon DUF5584 PF17822.1 ORY42133.1 - 0.041 13.3 0.3 0.32 10.4 0.1 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5584) Transp_cyt_pur PF02133.15 ORY42135.1 - 6.9e-21 74.5 29.5 1.2e-20 73.7 29.5 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF973 PF06157.11 ORY42135.1 - 0.061 12.4 6.3 0.85 8.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF973) SpoV PF08183.11 ORY42135.1 - 2.7 8.0 5.0 5 7.1 0.7 3.1 3 0 0 3 3 3 0 Stage V sporulation protein family Exo70 PF03081.15 ORY42136.1 - 7.1e-68 229.4 0.0 1e-67 228.8 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Sec3_C PF09763.9 ORY42136.1 - 0.0016 16.9 0.4 0.0027 16.2 0.4 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 HSBP1 PF06825.12 ORY42136.1 - 0.12 12.3 0.6 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 MFS_1 PF07690.16 ORY42137.1 - 5.6e-17 61.7 23.2 1.3e-16 60.5 21.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY42137.1 - 5.4e-11 42.5 1.7 1.6e-10 41.0 1.4 1.9 2 0 0 2 2 2 1 Nodulin-like DUF2104 PF09877.9 ORY42137.1 - 0.23 11.7 1.8 3.9 7.8 0.1 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2104) FA_desaturase PF00487.24 ORY42441.1 - 1.6e-11 44.5 0.1 2.1e-11 44.2 0.1 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Complex1_51K PF01512.17 ORY42442.1 - 2.5e-47 160.5 0.0 5.2e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ORY42442.1 - 8.2e-32 109.1 0.2 1.5e-31 108.2 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ORY42442.1 - 2.5e-08 33.6 0.0 6.2e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain DEAD PF00270.29 ORY42443.1 - 2.7e-19 69.6 0.0 4.4e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY42443.1 - 4.8e-15 55.9 0.0 1.8e-11 44.3 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORY42443.1 - 7.8e-11 42.5 0.8 2.4e-10 41.0 0.8 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 ORY42443.1 - 0.00073 19.6 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY42443.1 - 0.037 14.3 0.1 0.18 12.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF1660 PF07874.11 ORY42443.1 - 0.076 13.5 0.0 0.29 11.7 0.0 2.0 1 0 0 1 1 1 0 Prophage protein (DUF1660) F-box PF00646.33 ORY42444.1 - 4.8e-06 26.3 0.1 4.8e-06 26.3 0.1 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORY42444.1 - 0.00025 20.9 0.2 0.00025 20.9 0.2 2.0 2 0 0 2 2 2 1 F-box-like Pheromone PF08015.11 ORY42444.1 - 8.9 7.4 11.9 6.7 7.8 1.3 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone zf-CCCH_4 PF18044.1 ORY42445.1 - 3.3e-06 26.8 6.5 0.00053 19.7 0.5 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY42445.1 - 0.00027 20.9 7.2 0.14 12.3 1.2 2.7 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORY42445.1 - 0.0052 16.7 7.0 0.078 12.9 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 ORY42445.1 - 0.007 16.8 5.1 0.0075 16.7 0.9 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY42445.1 - 0.015 16.0 5.0 0.9 10.3 0.5 2.3 1 1 1 2 2 2 0 Torus domain DUF4775 PF16001.5 ORY42446.1 - 2.9 7.2 7.4 3.7 6.9 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) zf-His_Me_endon PF05551.11 ORY42447.1 - 4.4e-14 52.8 2.7 8.2e-14 51.9 2.7 1.4 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease HNH_3 PF13392.6 ORY42447.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease RhoGEF PF00621.20 ORY42449.1 - 6.5e-32 111.2 0.0 2.9e-31 109.1 0.0 2.0 1 1 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 ORY42449.1 - 3.4e-07 29.9 0.2 0.0022 17.7 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY42449.1 - 9.2e-07 29.1 0.1 0.058 13.8 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Brix PF04427.18 ORY42452.1 - 1.1e-23 84.3 0.1 1.5e-23 83.9 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.9 ORY42452.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) adh_short PF00106.25 ORY42706.1 - 9.7e-23 80.6 0.0 1.2e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY42706.1 - 5.7e-16 58.8 0.0 6.6e-16 58.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY42706.1 - 1.9e-08 34.4 0.0 2.5e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY42706.1 - 4.3e-05 23.5 0.1 4.5e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY42706.1 - 0.0035 16.6 0.3 0.01 15.0 0.3 1.7 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 ORY42706.1 - 0.02 14.3 0.1 0.033 13.6 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family QWRF PF04484.12 ORY42707.1 - 2.7 7.7 8.8 3 7.5 8.8 1.2 1 0 0 1 1 1 0 QWRF family PBP_N PF17093.5 ORY42707.1 - 5.2 7.3 13.1 64 3.8 13.1 2.1 1 1 0 1 1 1 0 Penicillin-binding protein N-terminus Apt1 PF10351.9 ORY42707.1 - 6.4 5.5 6.5 7.5 5.3 6.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain UPF0183 PF03676.14 ORY42709.1 - 2.4e-67 227.9 0.0 4.1e-67 227.2 0.0 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) F-box-like PF12937.7 ORY42710.1 - 0.00018 21.3 0.1 0.00043 20.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like NOA36 PF06524.12 ORY42710.1 - 0.16 11.3 4.0 0.25 10.6 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 ORY42710.1 - 0.34 11.1 8.1 5.9 7.1 7.7 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 EF1_GNE PF00736.19 ORY42711.1 - 9.7e-30 102.6 1.5 2e-29 101.6 1.5 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ORY42711.1 - 1.6e-13 50.8 6.0 1.6e-13 50.8 6.0 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region DUF3246 PF11596.8 ORY42711.1 - 0.022 14.2 1.9 0.075 12.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) GST_C_2 PF13410.6 ORY42711.1 - 0.024 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_3_C PF01915.22 ORY42711.1 - 0.053 13.5 3.6 0.056 13.4 2.8 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain SPT2 PF08243.11 ORY42711.1 - 0.061 13.9 0.7 0.061 13.9 0.7 2.0 2 0 0 2 2 2 0 SPT2 chromatin protein F-box-like PF12937.7 ORY42712.1 - 3.7e-12 45.9 0.6 9.8e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 ORY42712.1 - 7.8e-08 32.0 2.2 0.01 15.7 0.1 2.5 2 0 0 2 2 2 2 F-box domain F-box_5 PF18511.1 ORY42712.1 - 0.00012 21.6 0.1 0.87 9.2 0.0 2.9 2 0 0 2 2 2 2 F-box ThiS PF02597.20 ORY42712.1 - 0.064 13.9 0.0 7.9 7.2 0.0 2.7 2 0 0 2 2 2 0 ThiS family UPF0160 PF03690.13 ORY42713.1 - 2.9e-133 444.4 0.0 3.3e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF2013 PF09431.10 ORY42714.1 - 1.6e-52 177.3 0.0 4.9e-52 175.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) adh_short PF00106.25 ORY42716.1 - 2.5e-31 108.6 0.0 3.3e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY42716.1 - 8.6e-20 71.3 0.0 1.2e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY42716.1 - 6.5e-10 39.2 0.0 1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 ORY42716.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 ORY42716.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CRCB PF02537.15 ORY42717.1 - 4.4e-29 100.7 18.5 1.4e-17 63.8 2.7 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) BaxI_1 PF12811.7 ORY42717.1 - 0.033 13.8 2.6 0.076 12.6 0.0 2.4 1 1 2 3 3 3 0 Bax inhibitor 1 like Ferritin_2 PF13668.6 ORY42718.1 - 1.3e-32 112.8 1.3 1.8e-32 112.4 1.3 1.1 1 0 0 1 1 1 1 Ferritin-like domain F-box-like PF12937.7 ORY42720.1 - 2.4e-05 24.1 0.1 0.00021 21.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY42720.1 - 0.04 13.8 1.4 0.11 12.4 0.6 2.1 2 1 0 2 2 2 0 F-box domain WD40 PF00400.32 ORY42721.1 - 9.2e-11 42.1 16.3 0.00013 22.6 0.3 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat SDA1 PF05285.12 ORY42721.1 - 0.071 12.5 7.7 0.1 12.0 7.7 1.1 1 0 0 1 1 1 0 SDA1 SRAP PF02586.14 ORY42722.1 - 8.7e-36 123.5 0.2 1e-35 123.3 0.2 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Zn_clus PF00172.18 ORY42972.1 - 1.6e-09 37.7 9.1 1.6e-09 37.7 9.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 ORY42972.1 - 0.017 15.5 0.4 0.017 15.5 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY42972.1 - 0.022 15.0 0.6 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 ORY42972.1 - 0.06 13.8 0.1 0.06 13.8 0.1 3.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 ORY42972.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY42972.1 - 0.52 11.3 0.1 0.52 11.3 0.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger F-box-like PF12937.7 ORY42974.1 - 3.7e-07 29.9 0.4 1.5e-06 28.0 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY42974.1 - 0.00018 21.3 0.1 0.00056 19.7 0.1 1.8 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 ORY42975.1 - 1.4e-50 167.1 12.7 3.8e-06 26.5 0.0 9.7 9 1 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY42975.1 - 2.1e-43 142.9 10.6 9.1e-05 22.3 0.0 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY42975.1 - 2.7e-36 120.7 7.9 1.7e-05 24.7 0.0 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.6 ORY42975.1 - 3.4e-27 92.8 3.5 0.0039 17.9 0.4 7.9 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY42975.1 - 8.2e-22 77.6 5.3 0.00013 22.5 0.0 7.7 6 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 ORY42975.1 - 2.6e-21 74.4 9.1 0.00018 21.6 0.0 10.0 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY42975.1 - 1.4e-19 68.6 4.5 0.11 12.6 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 ORY42975.1 - 7.7e-18 63.9 6.7 0.21 12.3 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY42975.1 - 1.5e-17 63.7 11.0 0.00095 19.4 0.1 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY42975.1 - 1.3e-16 60.9 2.4 0.099 13.2 0.0 6.9 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY42975.1 - 2.9e-16 58.8 21.8 1.1e-05 25.0 1.0 8.6 5 3 5 10 10 10 4 TPR repeat TPR_9 PF13371.6 ORY42975.1 - 8.8e-15 54.6 2.5 0.009 16.1 0.0 5.9 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_15 PF13429.6 ORY42975.1 - 8.6e-08 31.7 4.6 0.092 11.9 0.3 4.8 2 2 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY42975.1 - 4.6e-06 26.8 2.9 0.001 19.3 0.1 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 ORY42975.1 - 0.0033 17.1 3.7 0.32 10.7 0.1 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 ORY42975.1 - 0.032 14.1 9.0 16 5.5 0.1 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.10 ORY42975.1 - 0.04 12.9 0.1 0.26 10.2 0.0 2.1 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Cohesin_load PF10345.9 ORY42975.1 - 0.049 12.1 0.1 4.2 5.7 0.0 2.9 2 1 1 3 3 3 0 Cohesin loading factor DUF2225 PF09986.9 ORY42975.1 - 0.1 12.3 0.5 0.33 10.6 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF1965 PF09248.10 ORY42975.1 - 1.1 9.1 4.2 37 4.2 0.3 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF1965) RRM_1 PF00076.22 ORY42976.1 - 1.2e-80 265.3 3.5 2.3e-20 72.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY42976.1 - 3.6e-29 100.7 1.6 8.2e-29 99.6 1.6 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 ORY42976.1 - 4.4e-06 26.7 0.4 12 6.1 0.0 4.9 4 2 0 4 4 4 3 RNA recognition motif RRM_3 PF08777.11 ORY42976.1 - 2.2e-05 24.5 3.6 0.044 13.8 1.2 4.0 4 0 0 4 4 4 1 RNA binding motif RRM_occluded PF16842.5 ORY42976.1 - 0.00045 20.0 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY42976.1 - 0.026 14.5 0.4 21 5.2 0.0 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 ORY42976.1 - 0.07 12.8 4.7 4.9 6.9 0.7 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain BAR PF03114.18 ORY42977.1 - 3.7e-36 125.0 2.1 6.4e-36 124.2 2.1 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY42977.1 - 2.6e-14 52.5 0.1 4.4e-14 51.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY42977.1 - 3.4e-13 49.2 0.1 5.5e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY42977.1 - 1.4e-08 34.3 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain FAM92 PF06730.11 ORY42977.1 - 9.2e-05 22.0 2.8 0.00018 21.0 1.8 1.8 1 1 1 2 2 2 1 FAM92 protein Sec34 PF04136.15 ORY42977.1 - 0.0042 17.0 3.8 0.042 13.7 2.4 2.4 2 1 0 2 2 2 1 Sec34-like family Tho2 PF11262.8 ORY42977.1 - 0.015 14.6 2.1 0.023 13.9 2.1 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PHM7_cyt PF14703.6 ORY42977.1 - 0.12 12.6 1.3 0.3 11.3 1.3 1.7 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter OmpH PF03938.14 ORY42977.1 - 0.8 10.0 6.1 2.4 8.5 6.1 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SBDS_C PF09377.10 ORY42978.1 - 6.5e-37 126.1 0.0 1.2e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 ORY42978.1 - 4.4e-32 110.0 0.2 9e-32 109.0 0.2 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Glyco_trans_4_4 PF13579.6 ORY42979.1 - 2.3e-10 41.2 2.8 2.3e-10 41.2 2.8 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ORY42979.1 - 1.1e-08 35.6 0.0 2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY42979.1 - 4.5e-05 23.5 1.1 7.7e-05 22.8 1.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ORY42979.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORY42979.1 - 0.0019 18.5 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 bZIP_1 PF00170.21 ORY42980.1 - 8.1e-05 22.6 10.3 0.00013 21.9 10.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY42980.1 - 0.0016 18.4 10.7 0.053 13.6 10.5 2.4 1 1 0 1 1 1 1 Basic region leucine zipper SpoIIIAH PF12685.7 ORY42980.1 - 0.089 12.6 2.3 0.17 11.7 2.3 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop53 PF07767.11 ORY42980.1 - 0.69 9.2 13.2 1.1 8.5 13.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Fungal_trans PF04082.18 ORY42981.1 - 5.1e-21 74.9 0.0 8.6e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY42981.1 - 2.1e-08 34.1 8.0 3.7e-08 33.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.21 ORY42982.1 - 1.8e-36 123.5 12.6 6.3e-09 35.4 0.0 5.5 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat DND1_DSRM PF14709.7 ORY43248.1 - 0.0045 17.2 0.3 6.4 7.1 0.0 4.1 4 0 0 4 4 4 2 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 ORY43248.1 - 1.9 9.3 7.6 8.3 7.2 0.0 4.2 5 0 0 5 5 5 0 Double-stranded RNA binding motif DNA_pol3_delta2 PF13177.6 ORY43249.1 - 2e-11 43.9 0.1 3.8e-11 43.1 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ORY43249.1 - 5.9e-07 30.0 0.1 1.6e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 ORY43249.1 - 0.00035 20.9 0.0 0.00096 19.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 ORY43249.1 - 0.0019 18.0 0.2 0.003 17.4 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 ORY43249.1 - 0.0081 16.5 0.0 0.024 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 ORY43249.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_22 PF13401.6 ORY43249.1 - 0.016 15.4 0.6 0.072 13.4 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY43249.1 - 0.026 14.9 1.4 0.31 11.4 1.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain HWE_HK PF07536.14 ORY43249.1 - 0.027 15.2 0.0 11 6.8 0.0 3.0 2 0 0 2 2 2 0 HWE histidine kinase RuvB_N PF05496.12 ORY43249.1 - 0.093 12.5 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Nterm_IS4 PF13006.7 ORY43249.1 - 0.13 12.5 0.2 0.54 10.5 0.0 2.1 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal CXCL17 PF15211.6 ORY43250.1 - 0.39 11.5 0.1 0.39 11.5 0.1 2.2 2 0 0 2 2 2 0 VEGF co-regulated chemokine 1 UPF0242 PF06785.11 ORY43250.1 - 3.6 7.6 15.9 7 6.7 15.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_L12_N PF16320.5 ORY43251.1 - 0.02 14.6 0.3 0.02 14.6 0.3 3.5 3 1 1 4 4 4 0 Ribosomal protein L7/L12 dimerisation domain UQ_con PF00179.26 ORY43252.1 - 9.1e-37 125.8 0.0 1.1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NOA36 PF06524.12 ORY43252.1 - 7 5.9 8.9 8.5 5.6 8.9 1.1 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 ORY43253.1 - 2.1 7.8 5.0 6.7 6.2 5.0 1.9 1 1 0 1 1 1 0 PPP4R2 Transglycosylas PF06737.14 ORY43254.1 - 1.2 9.8 3.9 1.8 9.3 0.6 2.8 3 1 1 4 4 4 0 Transglycosylase-like domain DUF1622 PF07784.11 ORY43255.1 - 0.091 12.7 0.1 0.091 12.7 0.1 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1622) Lysis_col PF02402.16 ORY43255.1 - 0.11 12.2 0.3 0.7 9.6 0.3 2.5 1 0 0 1 1 1 0 Lysis protein Ribosomal_L5_C PF00673.21 ORY43256.1 - 7.3e-27 93.4 0.0 1e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus DUF4115 PF13464.6 ORY43256.1 - 0.095 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) Ribosomal_L5 PF00281.19 ORY43256.1 - 0.25 11.7 0.3 19 5.7 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein L5 Mito_carr PF00153.27 ORY43257.1 - 3.1e-31 107.1 4.0 1.6e-15 56.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyanate_lyase PF02560.14 ORY43257.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain zn-ribbon_14 PF16503.5 ORY43258.1 - 8.2e-15 54.0 5.6 8.2e-15 54.0 5.6 3.2 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 ORY43258.1 - 4.8e-13 49.3 0.0 8.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 PP-loop family Frag1 PF10277.9 ORY43259.1 - 1.1e-35 123.2 5.1 1.1e-35 123.2 5.1 3.0 5 0 0 5 5 5 1 Frag1/DRAM/Sfk1 family THEG4 PF15834.5 ORY43259.1 - 0.016 15.2 0.1 0.08 12.9 0.1 2.0 1 1 0 1 1 1 0 Testis highly expressed protein 4 SURF4 PF02077.15 ORY43259.1 - 0.17 11.5 0.2 1 8.9 0.0 2.1 2 0 0 2 2 2 0 SURF4 family adh_short_C2 PF13561.6 ORY43260.1 - 2.9e-61 207.0 0.0 3.4e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY43260.1 - 5.3e-51 172.9 0.0 6.5e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY43260.1 - 2.5e-12 47.1 0.3 8.6e-12 45.3 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY43260.1 - 0.00037 20.0 0.6 0.0022 17.5 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORY43260.1 - 0.0087 16.3 0.1 0.015 15.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF2325 PF10087.9 ORY43260.1 - 0.046 13.8 0.7 0.064 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) PH PF00169.29 ORY43261.1 - 0.00097 19.6 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 PH domain MRP-S27 PF10037.9 ORY43261.1 - 0.0026 16.7 0.8 0.0039 16.1 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 DUF5098 PF17023.5 ORY43261.1 - 0.024 13.6 0.2 0.27 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5098) DUF4771 PF15995.5 ORY43261.1 - 0.12 12.7 0.2 0.32 11.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Na_H_Exchanger PF00999.21 ORY43580.1 - 3.4e-59 200.6 41.7 5.6e-59 199.8 41.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FAR1 PF03101.15 ORY43581.1 - 3.4e-07 30.9 4.0 0.48 11.1 0.0 3.7 3 0 0 3 3 3 3 FAR1 DNA-binding domain DBD_Tnp_Mut PF03108.15 ORY43581.1 - 1.1 9.3 3.5 2.9 7.9 0.8 2.7 3 0 0 3 3 3 0 MuDR family transposase AFT PF08731.11 ORY43581.1 - 3.4 8.1 6.6 12 6.4 0.6 3.9 3 2 1 4 4 4 0 Transcription factor AFT Transglut_N PF00868.20 ORY43583.1 - 0.0066 16.8 0.0 0.019 15.3 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase family FAR1 PF03101.15 ORY43583.1 - 0.018 15.7 1.8 0.52 11.1 0.1 2.8 2 1 0 2 2 2 0 FAR1 DNA-binding domain Hydin_ADK PF17213.3 ORY43585.1 - 8.6 6.6 6.7 14 5.9 6.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain RWD PF05773.22 ORY43586.1 - 2.7e-18 66.4 1.1 6.7e-18 65.1 1.1 1.7 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 ORY43586.1 - 3.9e-07 30.4 9.3 8.2e-07 29.4 9.0 1.7 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 RNase_H PF00075.24 ORY43586.1 - 0.1 12.8 0.1 0.32 11.2 0.1 1.8 1 1 1 2 2 2 0 RNase H ArAE_2_N PF10337.9 ORY43586.1 - 0.18 10.8 0.1 0.22 10.5 0.1 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF2208 PF09973.9 ORY43586.1 - 0.3 10.7 2.5 2.2 7.8 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF2852 PF11014.8 ORY43587.1 - 0.11 12.7 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) KIAA1430 PF13879.6 ORY43587.1 - 0.16 12.7 1.9 0.34 11.7 1.9 1.5 1 0 0 1 1 1 0 KIAA1430 homologue TPP_enzyme_N PF02776.18 ORY43588.1 - 3.3e-54 183.1 0.0 2.3e-53 180.3 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORY43588.1 - 6.3e-46 155.9 0.3 7.7e-45 152.4 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY43588.1 - 4e-40 136.7 1.3 8.1e-40 135.7 0.4 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain CO_dh PF02552.16 ORY43588.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Abhydrolase_1 PF00561.20 ORY43589.1 - 6.5e-19 68.6 0.0 1.1e-17 64.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY43589.1 - 9.1e-14 52.6 1.5 1.2e-13 52.2 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY43589.1 - 1.7e-12 47.1 0.0 4e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ORY43589.1 - 0.0019 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 ORY43589.1 - 0.013 15.3 0.1 4.5 7.0 0.0 3.1 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase PGAP1 PF07819.13 ORY43589.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 ORY43589.1 - 0.072 12.7 0.1 0.72 9.5 0.1 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF915 PF06028.11 ORY43589.1 - 0.16 11.3 0.0 0.58 9.4 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 ORY43589.1 - 0.16 11.4 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 ORY43589.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DLH PF01738.18 ORY43589.1 - 0.21 11.1 0.0 14 5.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BolA PF01722.18 ORY43590.1 - 1.8e-29 101.9 0.3 2.1e-29 101.6 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein MazG PF03819.17 ORY43590.1 - 0.072 13.3 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Vac_Fusion PF02346.16 ORY43591.1 - 0.081 12.6 0.8 0.12 12.0 0.8 1.3 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 DUF5595 PF18077.1 ORY43591.1 - 0.093 12.8 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) SRP40_C PF05022.12 ORY43592.1 - 4.7e-29 101.0 0.4 9.7e-29 100.1 0.4 1.5 1 0 0 1 1 1 1 SRP40, C-terminal domain TFIIF_alpha PF05793.12 ORY43592.1 - 0.042 12.4 5.4 0.058 12.0 5.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Apt1 PF10351.9 ORY43592.1 - 0.16 10.8 5.7 0.15 10.8 5.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 ORY43592.1 - 0.29 9.6 7.4 0.28 9.7 7.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 ORY43592.1 - 0.47 10.4 12.9 0.68 9.9 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF1635 PF07795.11 ORY43592.1 - 1.8 8.4 8.9 2.3 8.0 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) HSF_DNA-bind PF00447.17 ORY43593.1 - 8.8e-31 106.4 1.1 2e-30 105.2 1.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 ORY43593.1 - 3.2e-24 85.2 0.0 6.8e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain GFO_IDH_MocA PF01408.22 ORY43930.1 - 4.1e-17 63.1 0.1 8e-17 62.2 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY43930.1 - 1.5e-07 31.5 0.0 2.4e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 ORY43930.1 - 0.023 14.9 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gly_transf_sug PF04488.15 ORY43931.1 - 8.3e-09 36.0 0.0 1.5e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY43931.1 - 1.2e-05 24.8 0.0 1.8e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORY43931.1 - 0.0001 21.7 0.1 0.00058 19.3 0.0 1.9 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Sporozoite_P67 PF05642.11 ORY43932.1 - 3 5.8 16.7 3.8 5.5 16.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_D_N PF18018.1 ORY43933.1 - 6.3e-41 139.5 0.0 9.7e-41 138.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 ORY43933.1 - 4.2e-39 134.1 0.0 5.6e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B BTB PF00651.31 ORY43936.1 - 4.2e-05 23.7 0.0 0.00033 20.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain CENP-B_dimeris PF09026.10 ORY43936.1 - 0.03 14.7 4.7 0.062 13.7 4.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 ORY43936.1 - 0.75 9.5 12.3 1.2 8.8 12.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop25 PF09805.9 ORY43936.1 - 1.6 9.2 9.8 3.1 8.3 9.8 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Nop14 PF04147.12 ORY43936.1 - 6.2 4.9 17.4 9 4.4 17.4 1.1 1 0 0 1 1 1 0 Nop14-like family AA_permease PF00324.21 ORY43937.1 - 1.6e-114 383.2 35.1 1.8e-114 383.0 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY43937.1 - 7.1e-33 114.1 41.3 9.7e-33 113.6 41.3 1.2 1 0 0 1 1 1 1 Amino acid permease BTB PF00651.31 ORY43938.1 - 4.2e-05 23.7 0.0 6.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 ORY43939.1 - 1.3e-07 31.8 0.0 0.00095 19.4 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Mpp10 PF04006.12 ORY43939.1 - 0.054 11.9 14.5 0.076 11.5 14.5 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 ORY43939.1 - 0.72 9.1 20.7 1.1 8.5 20.7 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORY43939.1 - 1.4 8.3 19.7 2.6 7.4 19.7 1.4 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 ORY43939.1 - 5.1 4.1 6.0 6.7 3.7 6.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 ORY43939.1 - 6.2 5.0 12.6 12 4.0 12.6 1.4 1 0 0 1 1 1 0 CDC45-like protein AMP-binding PF00501.28 ORY43940.1 - 6.4e-72 242.5 0.0 8.2e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY43940.1 - 1.6e-17 64.3 0.4 3e-17 63.4 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 ORY43940.1 - 0.021 13.7 0.0 0.057 12.3 0.0 1.6 2 0 0 2 2 2 0 GH3 auxin-responsive promoter HHH PF00633.23 ORY43940.1 - 0.28 11.2 0.8 12 6.0 0.2 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif TraI_2B PF18340.1 ORY43942.1 - 0.23 11.6 1.4 0.35 11.0 0.8 1.6 2 0 0 2 2 2 0 DNA relaxase TraI 2B/2B-like domain AAA_22 PF13401.6 ORY44270.1 - 0.00012 22.4 0.2 0.00035 20.8 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY44270.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ORY44270.1 - 0.0002 21.2 0.1 0.0005 19.9 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 ORY44270.1 - 0.0043 16.2 0.0 0.0072 15.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 ORY44270.1 - 0.0045 16.7 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORY44270.1 - 0.0051 16.1 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ORY44270.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY44270.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ORY44270.1 - 0.056 12.9 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 ORY44270.1 - 0.1 12.9 1.0 0.28 11.6 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain ResIII PF04851.15 ORY44270.1 - 0.1 12.6 0.0 23 4.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Microtub_bd PF16796.5 ORY44270.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding TrwB_AAD_bind PF10412.9 ORY44270.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.6 ORY44270.1 - 0.15 12.2 0.7 0.48 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY44271.1 - 1.2e-08 35.4 0.1 2e-07 31.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain UvrD_C PF13361.6 ORY44271.1 - 1.9e-07 30.8 0.0 0.013 14.9 0.0 3.3 2 1 1 3 3 3 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 ORY44271.1 - 2.3e-07 30.7 0.1 6.1e-06 26.0 0.0 2.8 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 ORY44271.1 - 0.00066 19.5 0.1 1.8 8.5 0.1 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 ORY44271.1 - 0.013 15.8 0.5 7.9 6.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain zf-CCCH PF00642.24 ORY44271.1 - 0.12 12.3 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SNAP PF14938.6 ORY44271.1 - 0.13 11.7 5.3 0.24 10.8 5.3 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 ORY44271.1 - 0.96 9.6 3.0 23 5.3 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 ORY44274.1 - 3.4e-08 33.2 9.7 3.4e-08 33.2 9.7 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY44274.1 - 0.01 15.7 7.4 0.01 15.7 7.4 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF971 PF06155.12 ORY44274.1 - 0.014 16.0 0.1 0.014 16.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF971) Rxt3 PF08642.10 ORY44274.1 - 0.072 13.9 0.1 0.16 12.8 0.1 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 SUIM_assoc PF16619.5 ORY44274.1 - 0.45 10.6 17.9 1.3e+02 2.7 20.6 3.3 2 2 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DUF5308 PF17233.2 ORY44274.1 - 0.6 10.3 12.0 0.15 12.3 8.6 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Presenilin PF01080.17 ORY44274.1 - 0.77 8.5 3.2 1.5 7.5 3.2 1.4 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 ORY44274.1 - 6.1 5.9 11.2 15 4.6 11.2 1.7 1 0 0 1 1 1 0 RAM signalling pathway protein Spt20 PF12090.8 ORY44274.1 - 7.5 6.1 15.4 18 4.8 15.4 1.6 1 0 0 1 1 1 0 Spt20 family Ndc1_Nup PF09531.10 ORY44274.1 - 9.9 4.7 8.8 15 4.1 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup E1_dh PF00676.20 ORY44275.1 - 2.3e-113 378.1 0.0 2.9e-113 377.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORY44275.1 - 0.0097 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Endonuclease_NS PF01223.23 ORY44276.1 - 2.7e-56 190.9 0.0 3.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease COX4 PF02936.14 ORY44277.1 - 5.1e-35 120.5 0.2 6.1e-35 120.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV HTH_1 PF00126.27 ORY44277.1 - 0.35 10.9 2.1 0.82 9.7 2.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family ABC_tran PF00005.27 ORY44278.1 - 4.1e-43 147.2 0.5 4.6e-22 79.0 0.1 3.0 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY44278.1 - 1.4e-22 79.5 5.8 1.4e-22 79.5 5.8 3.2 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 ORY44278.1 - 2.4e-16 60.4 6.5 0.0017 18.3 0.1 4.6 5 0 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY44278.1 - 5.5e-13 48.9 0.3 3.9e-05 23.2 0.1 4.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY44278.1 - 2.2e-07 30.5 0.6 0.02 14.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY44278.1 - 2.9e-06 27.4 0.8 0.15 12.2 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY44278.1 - 0.00036 20.8 0.0 1.9 8.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 ORY44278.1 - 0.00048 20.1 5.5 0.46 10.4 0.3 3.3 2 1 0 2 2 2 2 RsgA GTPase DUF815 PF05673.13 ORY44278.1 - 0.00052 19.3 0.2 0.53 9.4 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_15 PF13175.6 ORY44278.1 - 0.00071 19.4 7.2 0.18 11.5 0.0 3.7 4 1 1 5 5 5 2 AAA ATPase domain NACHT PF05729.12 ORY44278.1 - 0.0015 18.5 0.0 2.2 8.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MeaB PF03308.16 ORY44278.1 - 0.0018 17.3 1.8 0.22 10.4 0.0 2.8 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 ORY44278.1 - 0.0025 18.2 3.9 0.3 11.5 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 ORY44278.1 - 0.0028 18.1 0.9 3.4 8.1 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY44278.1 - 0.0029 18.0 0.0 0.96 9.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 ORY44278.1 - 0.0058 17.2 2.0 6.2 7.4 0.0 4.1 4 1 0 4 4 4 0 AAA domain MukB PF04310.12 ORY44278.1 - 0.0064 16.3 0.9 1.7 8.4 0.0 3.3 3 0 0 3 3 3 1 MukB N-terminal AAA_28 PF13521.6 ORY44278.1 - 0.0079 16.5 4.4 1.1 9.5 0.1 3.2 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 ORY44278.1 - 0.018 14.4 1.2 0.71 9.2 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_14 PF13173.6 ORY44278.1 - 0.019 15.0 0.0 6.4 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY44278.1 - 0.019 15.1 3.2 3.2 7.9 0.0 3.6 3 1 1 4 4 4 0 AAA domain AAA_24 PF13479.6 ORY44278.1 - 0.019 14.7 0.0 7.8 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORY44278.1 - 0.026 14.6 0.0 0.026 14.6 0.0 3.7 5 0 0 5 5 5 0 Helicase HerA, central domain AAA_23 PF13476.6 ORY44278.1 - 0.03 14.8 0.1 0.31 11.5 0.0 4.6 5 0 0 5 5 5 0 AAA domain Dynamin_N PF00350.23 ORY44278.1 - 0.048 13.7 3.5 8.4 6.4 0.1 3.4 4 1 0 4 4 4 0 Dynamin family AAA_27 PF13514.6 ORY44278.1 - 0.078 12.6 1.3 16 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 ORY44278.1 - 0.12 12.6 0.8 7 7.0 0.2 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 ORY44278.1 - 0.16 11.9 0.4 43 4.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2813 PF11398.8 ORY44278.1 - 0.78 8.9 5.7 9.5 5.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) UCH PF00443.29 ORY44279.1 - 1.6e-40 139.3 0.0 6.7e-40 137.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY44279.1 - 1.5e-09 37.9 0.0 3.3e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C28 PF05408.11 ORY44279.1 - 0.28 10.9 0.0 7.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Foot-and-mouth virus L-proteinase DND1_DSRM PF14709.7 ORY44281.1 - 0.00038 20.7 0.0 0.29 11.4 0.0 3.0 2 0 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 Pkinase PF00069.25 ORY44283.1 - 3.4e-12 46.3 0.0 3.8e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44283.1 - 1.1e-10 41.2 0.0 1.1e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Aldedh PF00171.22 ORY44641.1 - 2.4e-70 237.4 0.0 2.9e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CDC73_C PF05179.14 ORY44642.1 - 7.6e-55 184.9 1.2 1.3e-54 184.2 1.2 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 ORY44642.1 - 0.0025 17.2 0.0 0.013 14.8 0.0 2.1 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal BOP1NT PF08145.12 ORY44642.1 - 0.046 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 BOP1NT (NUC169) domain COX6B PF02297.17 ORY44643.1 - 2.7e-18 66.0 4.9 3.2e-18 65.7 4.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prp18 PF02840.15 ORY44644.1 - 1.1e-59 200.6 0.0 1.1e-59 200.6 0.0 1.6 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 ORY44644.1 - 1e-10 41.0 6.3 2.5e-10 39.7 6.3 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Miga PF10265.9 ORY44644.1 - 0.57 9.1 4.4 1.1 8.1 0.2 2.2 1 1 1 2 2 2 0 Mitoguardin F-box-like PF12937.7 ORY44645.1 - 0.014 15.2 0.3 0.049 13.5 0.3 2.0 1 0 0 1 1 1 0 F-box-like Ribosomal_S13_N PF08069.12 ORY44646.1 - 8.9e-30 102.5 0.1 2.2e-29 101.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORY44646.1 - 7.3e-14 51.7 0.7 9.8e-14 51.3 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 ORY44646.1 - 0.14 12.1 0.1 0.4 10.6 0.0 1.7 1 1 0 2 2 2 0 'Paired box' domain Hepar_II_III_N PF16889.5 ORY44646.1 - 0.18 11.0 0.0 1.6 7.9 0.0 2.1 2 1 0 2 2 2 0 Heparinase II/III N-terminus Aldedh PF00171.22 ORY44647.1 - 5.8e-140 466.9 0.1 7.3e-140 466.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY44647.1 - 0.036 13.5 0.0 3 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ribosomal_S6e PF01092.19 ORY44648.1 - 4.1e-56 188.3 0.1 6.7e-56 187.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Methyltransf_15 PF09445.10 ORY44650.1 - 3.6e-35 121.0 0.0 4.4e-28 97.9 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 ORY44650.1 - 2.2e-06 28.3 0.0 4.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY44650.1 - 0.00015 21.6 0.0 0.00024 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ORY44650.1 - 0.00092 19.0 0.1 0.0042 16.9 0.0 2.0 2 1 1 3 3 3 1 Met-10+ like-protein Methyltransf_18 PF12847.7 ORY44650.1 - 0.0038 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ORY44650.1 - 0.0051 16.5 0.1 0.044 13.5 0.1 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.12 ORY44650.1 - 0.02 15.5 0.0 0.037 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 ORY44650.1 - 0.021 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_8 PF05148.15 ORY44650.1 - 0.063 13.1 0.0 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.13 ORY44650.1 - 0.17 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 ORY44650.1 - 0.19 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TRM PF02005.16 ORY44650.1 - 0.21 10.7 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Ribosomal_S15 PF00312.22 ORY44652.1 - 3e-07 30.5 2.4 3.8e-07 30.2 2.4 1.3 1 1 0 1 1 1 1 Ribosomal protein S15 SPC25 PF06703.11 ORY44653.1 - 2.7e-51 173.6 0.0 3.3e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Mito_fiss_reg PF05308.11 ORY44653.1 - 3.2 7.7 10.3 3.5 7.6 4.9 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator AAA_3 PF07726.11 ORY44654.1 - 0.048 13.5 0.1 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY44654.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MOSC PF03473.17 ORY44655.1 - 1.3e-25 90.0 0.0 1.7e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ORY44655.1 - 2.5e-14 53.2 0.0 3.5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF5422 PF17459.2 ORY44655.1 - 0.029 14.6 0.1 2.9 8.0 0.0 2.8 2 1 0 3 3 3 0 Family of unknown function (DUF5422) F-box-like PF12937.7 ORY44656.1 - 2.1e-06 27.5 0.2 4.5e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like SprT-like PF10263.9 ORY44656.1 - 0.058 13.2 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 SprT-like family F-box PF00646.33 ORY44656.1 - 0.6 10.1 4.1 2.7 8.0 1.5 2.4 2 0 0 2 2 2 0 F-box domain Pribosyltran_N PF13793.6 ORY44658.1 - 1.9e-38 130.9 0.0 1.2e-37 128.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORY44658.1 - 3.1e-37 128.4 1.5 3.1e-31 108.8 0.1 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORY44658.1 - 1.7e-11 43.9 1.7 3.6e-11 42.9 0.3 2.1 2 1 1 3 3 3 1 Phosphoribosyl transferase domain Methyltr_RsmB-F PF01189.17 ORY44659.1 - 2.8e-23 82.6 0.0 1.2e-22 80.6 0.0 1.9 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 ORY44659.1 - 0.0031 17.3 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain HpcH_HpaI PF03328.14 ORY44660.1 - 2.6e-33 115.0 0.0 3.4e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family FMN_dh PF01070.18 ORY44661.1 - 1.2e-11 44.2 0.0 1.3e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Adap_comp_sub PF00928.21 ORY45020.1 - 2.6e-40 138.5 0.0 3.6e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY45020.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MAM PF00629.23 ORY45020.1 - 0.14 12.1 0.2 0.28 11.1 0.0 1.5 2 0 0 2 2 2 0 MAM domain, meprin/A5/mu Aminotran_5 PF00266.19 ORY45021.1 - 3e-39 135.0 0.0 4.8e-39 134.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_71 PF03659.14 ORY45022.1 - 5.8e-82 275.5 4.3 5.8e-82 275.5 4.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 PPP4R2 PF09184.11 ORY45022.1 - 0.077 12.6 2.9 0.12 12.0 2.9 1.2 1 0 0 1 1 1 0 PPP4R2 BiPBP_C PF06832.12 ORY45022.1 - 0.24 11.4 1.4 7.8 6.6 0.0 3.0 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family SPX PF03105.19 ORY45022.1 - 2 8.2 8.1 3.2 7.6 8.1 1.3 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 ORY45022.1 - 4.2 5.8 6.1 5.5 5.4 6.1 1.2 1 0 0 1 1 1 0 Macoilin family TMEM154 PF15102.6 ORY45022.1 - 6.2 6.7 13.0 2.5e+02 1.5 12.8 2.5 1 1 0 1 1 1 0 TMEM154 protein family DUF2196 PF09962.9 ORY45023.1 - 1.8e-21 75.8 1.4 2.8e-21 75.2 1.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) UBA PF00627.31 ORY45023.1 - 0.0073 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 UBA/TS-N domain Zn_clus PF00172.18 ORY45024.1 - 0.00026 21.0 9.8 0.00044 20.3 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TAF PF02969.17 ORY45026.1 - 1e-27 96.1 0.1 1.6e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 ORY45026.1 - 7.5e-13 48.6 0.0 1.6e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TFIID-31kDa PF02291.15 ORY45026.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DPBB_1 PF03330.18 ORY45027.1 - 0.00025 21.2 0.0 0.00059 20.1 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase DUF572 PF04502.13 ORY45027.1 - 2.7 7.5 11.4 4.2 6.9 11.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Endomucin PF07010.12 ORY45027.1 - 2.9 7.8 44.3 2.3 8.1 42.9 1.4 2 0 0 2 2 2 0 Endomucin SpoIIIAH PF12685.7 ORY45027.1 - 3 7.6 12.8 5.2 6.8 12.8 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Macoilin PF09726.9 ORY45027.1 - 3.1 6.2 10.5 4.5 5.7 10.5 1.2 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 ORY45028.1 - 0.0018 19.0 4.4 53 4.9 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-MYND PF01753.18 ORY45031.1 - 2.2e-10 40.4 8.2 3.5e-10 39.8 8.2 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY45031.1 - 0.0091 16.3 7.4 0.077 13.3 7.4 2.2 1 1 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 ORY45032.1 - 5.2e-08 32.7 4.3 5.2e-08 32.7 4.3 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY45032.1 - 7.5e-05 23.0 2.7 0.024 15.1 0.0 5.0 4 3 3 7 7 7 1 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY45032.1 - 0.0057 16.5 0.9 0.022 14.7 0.9 2.1 1 0 0 1 1 1 1 F-box domain Glyco_transf_15 PF01793.16 ORY45033.1 - 1.4e-119 399.2 8.9 1.8e-119 398.8 8.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF5106 PF17127.4 ORY45033.1 - 0.091 13.0 0.3 0.19 12.0 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Tn7_TnsC_Int PF11426.8 ORY45033.1 - 0.47 10.7 2.7 1.2 9.4 1.3 2.2 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC Ras PF00071.22 ORY45034.1 - 3.4e-59 199.1 0.8 4.6e-59 198.7 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY45034.1 - 5.9e-37 126.6 0.1 1e-36 125.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY45034.1 - 2.1e-16 59.9 0.6 2.6e-16 59.6 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY45034.1 - 8.4e-07 28.7 0.3 4.4e-06 26.4 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY45034.1 - 7e-06 26.1 0.0 0.036 14.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORY45034.1 - 7.3e-06 25.5 0.1 1.1e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY45034.1 - 6.1e-05 23.1 0.1 0.00013 22.0 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY45034.1 - 0.00014 21.3 0.4 0.00018 20.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 ORY45034.1 - 0.0041 16.6 0.5 0.11 12.0 0.5 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ORY45034.1 - 0.0071 16.2 0.2 0.021 14.6 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ORY45034.1 - 0.059 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TAP42 PF04177.12 ORY45035.1 - 2.6e-82 276.5 4.9 2.9e-82 276.3 4.9 1.0 1 0 0 1 1 1 1 TAP42-like family ELM2 PF01448.24 ORY45035.1 - 0.09 13.5 2.2 0.12 13.1 0.0 2.4 2 1 0 2 2 2 0 ELM2 domain Herpes_gE PF02480.16 ORY45035.1 - 0.97 8.1 2.2 1.9 7.2 2.2 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CFEM PF05730.11 ORY45036.1 - 1.1e-09 38.2 14.2 2.2e-09 37.3 14.2 1.5 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.11 ORY45037.1 - 4e-09 36.4 13.1 8e-09 35.5 13.1 1.5 1 0 0 1 1 1 1 CFEM domain CHORD PF04968.12 ORY45038.1 - 1e-52 176.6 16.4 5.9e-27 94.2 4.6 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 ORY45038.1 - 1.4e-12 48.4 0.0 2.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 ORY45038.1 - 1.2 9.0 12.3 0.44 10.4 2.2 3.3 3 1 0 3 3 3 0 BTK motif CorA PF01544.18 ORY45039.1 - 3.7e-41 141.4 0.2 4.5e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 ORY45039.1 - 0.014 15.4 1.5 0.02 14.9 0.4 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.9 ORY45428.1 - 1.2e-25 89.9 0.0 4.1e-24 85.0 0.0 2.0 2 0 0 2 2 2 2 Apolipoprotein O ASF1_hist_chap PF04729.13 ORY45429.1 - 3.3e-65 218.7 0.0 4.1e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone DMSP_lyase PF16867.5 ORY45429.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase STE3 PF02076.15 ORY45430.1 - 8.5e-82 274.6 12.2 9.8e-82 274.4 12.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor FeoB_associated PF12669.7 ORY45430.1 - 0.25 11.8 0.8 24 5.4 0.1 2.5 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein NumbF PF06311.12 ORY45431.1 - 2 9.0 7.7 3.3 8.3 2.0 2.5 2 1 0 2 2 2 0 NUMB domain bZIP_Maf PF03131.17 ORY45431.1 - 4.3 7.9 10.0 12 6.5 2.6 2.3 2 0 0 2 2 2 0 bZIP Maf transcription factor Ribosomal_L18A PF01775.17 ORY45432.1 - 1.7e-44 150.8 0.7 2.1e-44 150.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF1891 PF09004.10 ORY45432.1 - 0.15 11.7 0.8 0.38 10.4 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1891) RRM_1 PF00076.22 ORY45433.1 - 2.6e-09 36.7 0.1 8.7e-05 22.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 ORY45433.1 - 4.1e-08 33.4 0.0 7.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 PWI domain Nup35_RRM_2 PF14605.6 ORY45433.1 - 1.4e-07 31.4 0.0 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY45433.1 - 0.0015 18.5 0.0 0.58 10.2 0.0 2.9 3 1 0 3 3 3 1 RNA binding motif zf-CCCH PF00642.24 ORY45433.1 - 0.0058 16.5 4.7 0.011 15.7 4.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY45433.1 - 0.075 13.7 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 Torus domain Limkain-b1 PF11608.8 ORY45433.1 - 0.1 12.7 0.1 0.64 10.1 0.0 2.3 3 0 0 3 3 3 0 Limkain b1 DUF4651 PF15513.6 ORY45433.1 - 0.21 11.5 0.0 8.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) zf_CCCH_4 PF18345.1 ORY45433.1 - 1.5 9.0 7.8 2.5 8.3 7.8 1.4 1 0 0 1 1 1 0 Zinc finger domain Ribosomal_S19 PF00203.21 ORY45434.1 - 6.1e-26 90.1 0.0 7.5e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 EMC1_C PF07774.13 ORY45435.1 - 1.3e-56 191.7 0.0 2.1e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 ORY45435.1 - 2.3e-10 40.5 4.8 1.3e-07 31.5 0.7 3.3 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.21 ORY45435.1 - 8e-05 22.4 0.9 11 6.2 0.0 5.3 6 0 0 6 6 6 2 PQQ enzyme repeat DDOST_48kD PF03345.14 ORY45436.1 - 7.2e-133 443.4 0.0 8e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta p450 PF00067.22 ORY45437.1 - 8e-57 193.0 0.0 1.1e-56 192.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_L PF01193.24 ORY45438.1 - 1.9e-20 72.1 0.0 2.5e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 ORY45438.1 - 4.2e-18 65.7 0.0 8.1e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain Ribosomal_L6 PF00347.23 ORY45439.1 - 1.7e-15 57.5 0.1 7.6e-09 36.1 0.0 3.4 3 1 0 3 3 3 2 Ribosomal protein L6 STE PF02200.16 ORY45440.1 - 4.3e-46 155.9 0.0 5.3e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 ORY45441.1 - 8.5e-12 44.8 5.9 7.5e-06 26.1 2.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY45441.1 - 6.5e-11 42.1 9.6 1.6e-10 40.9 3.2 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY45441.1 - 7.8e-09 35.6 4.9 0.0003 21.4 2.0 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY45441.1 - 1.2e-05 25.2 5.8 0.00014 21.7 0.1 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY45441.1 - 0.0015 18.8 0.1 0.45 10.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORY45441.1 - 0.0032 17.9 4.0 0.17 12.4 0.5 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 ORY45441.1 - 0.0066 16.5 1.1 0.015 15.4 1.1 1.6 1 1 0 1 1 1 1 Zinc ribbon domain zf-C2HC_2 PF13913.6 ORY45441.1 - 0.013 15.4 5.1 0.12 12.3 0.2 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.14 ORY45441.1 - 0.013 15.3 1.1 1.9 8.4 0.1 2.8 2 1 1 3 3 3 0 Zinc finger found in FPG and IleRS zf_C2H2_ZHX PF18387.1 ORY45441.1 - 0.022 14.4 1.9 0.34 10.6 0.5 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_9 PF14369.6 ORY45441.1 - 0.023 15.0 0.2 0.023 15.0 0.2 1.6 2 0 0 2 2 2 0 zinc-ribbon Ogr_Delta PF04606.12 ORY45441.1 - 0.023 14.7 0.2 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf_UBZ PF18439.1 ORY45441.1 - 0.044 13.4 1.6 0.21 11.2 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 ORY45441.1 - 0.05 13.9 3.6 0.12 12.7 3.6 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 ORY45441.1 - 0.058 13.4 0.1 0.17 11.9 0.1 1.8 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf-met PF12874.7 ORY45441.1 - 0.06 13.8 0.1 4.5 7.8 0.0 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 ORY45441.1 - 0.11 13.0 5.2 3.1 8.3 0.0 2.7 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Mito_carr PF00153.27 ORY45442.1 - 3e-65 216.2 1.0 3.5e-24 84.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.12 ORY45442.1 - 0.03 14.7 1.4 0.17 12.4 0.1 2.6 3 0 0 3 3 3 0 The GLUG motif ABC1 PF03109.16 ORY45443.1 - 4.3e-27 94.6 0.0 8.4e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 ORY45443.1 - 0.044 13.2 0.0 0.085 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain SpoVIF PF14069.6 ORY45443.1 - 0.2 11.4 0.0 0.52 10.1 0.0 1.7 1 0 0 1 1 1 0 Stage VI sporulation protein F ACT_3 PF10000.9 ORY45444.1 - 0.018 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45444.1 - 0.057 13.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY45444.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain ACT_3 PF10000.9 ORY45445.1 - 0.018 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45445.1 - 0.057 13.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY45445.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain ACT_3 PF10000.9 ORY45446.1 - 0.018 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45446.1 - 0.057 13.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY45446.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain ACT_3 PF10000.9 ORY45447.1 - 0.018 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45447.1 - 0.057 13.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY45447.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain ACT_3 PF10000.9 ORY45448.1 - 0.018 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45448.1 - 0.057 13.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY45448.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain DNA_pol_B_palm PF14792.6 ORY45449.1 - 3.6e-20 72.3 0.0 6.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ORY45449.1 - 1.6e-13 50.6 0.0 3.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ORY45449.1 - 4.3e-11 42.5 0.0 1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda EAP30 PF04157.16 ORY45449.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family ACT_3 PF10000.9 ORY45450.1 - 0.017 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45450.1 - 0.058 13.1 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY45450.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain ACT_3 PF10000.9 ORY45451.1 - 0.043 13.7 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45451.1 - 0.14 11.9 0.0 0.78 9.5 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain ACT_3 PF10000.9 ORY45452.1 - 0.017 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY45452.1 - 0.058 13.1 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY45452.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain Profilin PF00235.19 ORY45840.1 - 6.5e-44 149.3 0.2 7.1e-44 149.1 0.2 1.0 1 0 0 1 1 1 1 Profilin Frankia_peptide PF14407.6 ORY45840.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Robl_LC7 PF03259.17 ORY45840.1 - 0.087 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain TIM PF00121.18 ORY45841.1 - 6.9e-91 303.9 0.0 7.8e-91 303.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Got1 PF04178.12 ORY45842.1 - 2.4e-18 66.6 12.1 2.9e-18 66.3 12.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Metallophos PF00149.28 ORY45843.1 - 1.3e-10 42.1 0.3 2.3e-10 41.3 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 ORY45843.1 - 0.02 15.4 0.3 0.057 14.0 0.1 1.8 2 0 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain Ring_hydroxyl_A PF00848.19 ORY45844.1 - 8.8e-23 81.4 7.5 1.1e-21 77.8 4.1 2.6 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 ORY45844.1 - 3.9e-14 52.4 0.0 7.9e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CAMSAP_CH PF11971.8 ORY45844.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain TPR_1 PF00515.28 ORY45845.1 - 0.0071 16.1 0.0 0.045 13.6 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY45845.1 - 0.042 13.5 0.2 11 5.7 0.1 2.8 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 ORY45845.1 - 0.12 12.5 1.7 1.5 9.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY45845.1 - 0.31 11.3 2.1 1.2 9.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY45845.1 - 2.8 9.0 7.6 17 6.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Carn_acyltransf PF00755.20 ORY45846.1 - 1.2e-177 592.2 0.0 1.4e-177 592.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Solute_trans_a PF03619.16 ORY45847.1 - 7.4e-92 307.6 12.9 8.9e-92 307.4 12.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha F-box-like PF12937.7 ORY45849.1 - 0.00059 19.7 0.1 0.0012 18.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY45849.1 - 0.053 13.4 0.3 0.31 11.0 0.3 2.3 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.7 ORY45849.1 - 0.2 12.1 2.6 46 4.6 0.1 3.9 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) UBX PF00789.20 ORY45850.1 - 8.1e-13 48.4 0.0 1.5e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 ORY45850.1 - 1.1e-10 41.1 0.1 2.1e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 ORY45850.1 - 3.1e-05 24.1 0.1 8e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like DUF1682 PF07946.14 ORY45850.1 - 0.024 13.9 4.6 0.043 13.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RRN9 PF10680.9 ORY45850.1 - 0.48 10.7 2.8 1.4 9.2 2.8 1.9 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Glyco_hydro_88 PF07470.13 ORY45851.1 - 5.4e-18 65.2 0.0 7.9e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2849 PF11011.8 ORY45852.1 - 0.095 13.4 0.3 1.4 9.6 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) Flavokinase PF01687.17 ORY45853.1 - 9.5e-31 106.4 0.0 1.2e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Motile_Sperm PF00635.26 ORY46224.1 - 4.3e-18 65.2 0.0 4.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 ORY46224.1 - 0.00043 20.4 0.1 0.00052 20.2 0.1 1.1 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Alpha-amylase_C PF02806.18 ORY46224.1 - 0.012 16.1 0.0 0.015 15.8 0.0 1.1 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain TMEM131_like PF12371.8 ORY46224.1 - 0.067 13.5 0.0 0.081 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 131-like fn3_6 PF17766.1 ORY46224.1 - 0.082 13.1 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin type-III domain NAD_binding_4 PF07993.12 ORY46225.1 - 1.9e-36 125.6 0.0 2.7e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ORY46225.1 - 4.9e-25 88.0 0.0 8.4e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ORY46225.1 - 1.8e-10 40.7 0.0 4.9e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ORY46225.1 - 3e-07 30.7 0.0 8.5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 ORY46225.1 - 0.00024 21.1 0.1 0.0013 18.7 0.1 2.2 1 1 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ORY46225.1 - 0.0097 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 ORY46225.1 - 0.038 13.1 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Zn_clus PF00172.18 ORY46226.1 - 0.0021 18.1 5.0 0.0045 17.1 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3323 PF11796.8 ORY46226.1 - 0.025 14.5 0.3 0.057 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) PP2C PF00481.21 ORY46227.1 - 2.9e-80 269.6 0.0 3.8e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1479 PF07350.12 ORY46228.1 - 3.8e-143 477.2 0.0 4.5e-143 477.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Phage_holin_7_1 PF16081.5 ORY46228.1 - 0.029 14.6 0.1 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family PhyH PF05721.13 ORY46228.1 - 0.08 13.2 0.2 1.8 8.8 0.1 2.5 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Aldo_ket_red PF00248.21 ORY46229.1 - 1e-66 225.2 0.0 1.2e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPT PF03151.16 ORY46231.1 - 5.1e-16 58.9 18.3 9.9e-16 57.9 18.3 1.4 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY46231.1 - 0.0091 15.2 21.9 0.071 12.3 21.9 2.0 1 1 0 1 1 1 1 UAA transporter family IstB_IS21 PF01695.17 ORY46232.1 - 0.029 14.1 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein cobW PF02492.19 ORY46232.1 - 0.054 13.1 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain cobW PF02492.19 ORY46234.1 - 1.9e-20 73.2 0.0 3.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Pro_isomerase PF00160.21 ORY46236.1 - 3.4e-50 170.4 0.0 6.4e-50 169.5 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ORY46236.1 - 0.0017 19.2 0.0 4.2 8.4 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Zn_clus PF00172.18 ORY46237.1 - 4.2e-08 33.2 7.4 8.7e-08 32.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aurora-A_bind PF09041.10 ORY46237.1 - 0.033 14.2 0.0 6.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Aurora-A binding Sugarporin_N PF11471.8 ORY46237.1 - 0.25 11.3 1.4 8.6 6.4 0.1 2.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Transp_cyt_pur PF02133.15 ORY46238.1 - 4.8e-92 309.0 42.3 5.9e-92 308.7 42.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin FMN_dh PF01070.18 ORY46298.1 - 1.7e-123 412.1 0.0 2.2e-123 411.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY46298.1 - 4.5e-20 71.6 0.0 1.5e-19 69.9 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 ORY46298.1 - 8e-05 21.8 0.0 0.00038 19.6 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORY46298.1 - 0.00013 21.2 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 ORY46298.1 - 0.0073 15.5 0.0 0.27 10.4 0.0 2.4 2 1 0 3 3 3 1 Dihydroorotate dehydrogenase zf-RING_UBOX PF13445.6 ORY46299.1 - 5.4e-09 35.9 1.7 1.2e-08 34.8 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY46299.1 - 9.8e-08 31.7 2.4 9.8e-08 31.7 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY46299.1 - 1.2e-07 31.7 3.3 1.2e-07 31.7 3.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY46299.1 - 2.5e-07 30.5 1.2 2.5e-07 30.5 1.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY46299.1 - 1.1e-05 25.3 5.3 3.7e-05 23.6 2.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY46299.1 - 0.00015 22.0 2.9 0.00015 22.0 2.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY46299.1 - 0.0017 18.2 6.4 0.004 17.0 1.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORY46299.1 - 0.018 14.9 0.3 0.051 13.4 0.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 ORY46299.1 - 0.027 14.3 2.2 0.027 14.3 2.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 MALT1_Ig PF18703.1 ORY46299.1 - 0.13 12.3 0.9 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 MALT1 Ig-like domain zinc_ribbon_12 PF11331.8 ORY46299.1 - 0.85 9.5 4.3 7.9 6.4 0.6 3.2 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-RING_10 PF16685.5 ORY46299.1 - 7.7 6.7 8.6 0.82 9.9 4.2 1.6 2 0 0 2 2 1 0 zinc RING finger of MSL2 DEAD PF00270.29 ORY46300.1 - 8.4e-37 126.6 0.0 2.1e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY46300.1 - 1.5e-27 96.1 0.2 2.4e-26 92.3 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY46300.1 - 3.3e-08 33.7 0.0 6.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY46300.1 - 0.00098 18.5 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit zf-H2C2_2 PF13465.6 ORY46301.1 - 8.7e-10 38.6 5.3 3.8e-07 30.2 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY46301.1 - 1.3e-08 34.8 7.9 2.6e-06 27.5 0.5 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY46301.1 - 1.9e-06 28.2 5.3 7.1e-05 23.3 0.5 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY46301.1 - 0.00014 22.1 0.0 0.046 14.0 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY46301.1 - 0.00038 20.1 0.7 0.00038 20.1 0.7 1.8 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-met PF12874.7 ORY46301.1 - 0.001 19.4 1.7 0.11 13.0 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY46301.1 - 0.0033 17.4 0.4 0.0033 17.4 0.4 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY46301.1 - 0.025 14.3 0.5 0.025 14.3 0.5 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain GAGA PF09237.11 ORY46301.1 - 0.047 13.5 0.2 0.067 13.0 0.2 1.3 1 0 0 1 1 1 0 GAGA factor zf-C2HC_2 PF13913.6 ORY46301.1 - 0.14 12.1 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Hyr1 PF15789.5 ORY46303.1 - 0.95 9.1 3.9 15 5.2 0.3 2.4 2 0 0 2 2 2 0 Hyphally regulated cell wall GPI-anchored protein 1 DEAD PF00270.29 ORY46304.1 - 2.9e-15 56.5 0.0 5.9e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY46304.1 - 1.4e-12 47.9 0.0 3.9e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TMF_DNA_bd PF12329.8 ORY46304.1 - 0.11 12.5 0.9 8.5 6.5 0.4 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.12 ORY46304.1 - 0.63 10.1 4.9 1.4 9.0 0.9 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC24 PF15669.5 ORY46304.1 - 6.9 6.5 6.5 0.72 9.7 0.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Ribosomal_L19 PF01245.20 ORY46305.1 - 3.5e-08 33.4 0.2 6.7e-08 32.4 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L19 RPA PF10134.9 ORY46305.1 - 0.063 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Replication initiator protein A Pkinase PF00069.25 ORY46306.1 - 6.8e-75 251.8 0.0 8.6e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46306.1 - 2.7e-32 112.1 0.1 2.2e-22 79.6 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY46306.1 - 0.00017 21.1 0.1 0.54 9.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 ORY46306.1 - 0.05 12.4 0.0 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 ORY46306.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4646 PF15496.6 ORY46307.1 - 0.1 13.2 0.1 23 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Hexokinase_2 PF03727.16 ORY46308.1 - 2.2e-75 253.2 0.1 3.5e-75 252.5 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY46308.1 - 8.7e-72 241.2 0.1 1.3e-71 240.6 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Fungal_trans PF04082.18 ORY46309.1 - 1e-16 60.8 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY46309.1 - 0.00012 22.2 6.0 0.00021 21.4 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin PF08613.11 ORY46312.1 - 4.5e-08 33.6 0.0 4.8e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY46312.1 - 0.044 13.5 0.0 0.047 13.4 0.0 1.0 1 0 0 1 1 1 0 Cyclin, N-terminal domain SOG2 PF10428.9 ORY46694.1 - 1.4e-23 83.9 0.0 1.7e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein Mntp PF02659.15 ORY46695.1 - 0.042 13.6 0.2 0.075 12.8 0.2 1.3 1 0 0 1 1 1 0 Putative manganese efflux pump DUF3088 PF11287.8 ORY46695.1 - 0.19 11.5 0.0 0.59 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3088) tRNA-synt_1c PF00749.21 ORY46696.1 - 3.1e-99 331.8 0.0 4.5e-99 331.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 ORY46696.1 - 1.6e-30 106.2 0.8 2.1e-30 105.9 0.0 1.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 ORY46696.1 - 5.4e-28 98.0 0.0 4.9e-27 94.9 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 ORY46696.1 - 0.0056 17.6 1.1 0.025 15.5 0.1 2.3 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DNA_ligase_IV PF11411.8 ORY46696.1 - 0.069 13.3 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 DNA ligase IV LTV PF04180.14 ORY46701.1 - 3.2e-89 300.3 18.1 1.8e-82 278.1 11.6 2.2 1 1 1 2 2 2 2 Low temperature viability protein Yip1 PF04893.17 ORY46702.1 - 1.8e-10 40.8 13.4 2.6e-10 40.3 13.4 1.3 1 0 0 1 1 1 1 Yip1 domain Rav1p_C PF12234.8 ORY46703.1 - 2.8e-173 577.8 0.0 3.6e-173 577.4 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 ORY46703.1 - 8.9 7.4 11.1 21 6.2 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat Fungal_trans_2 PF11951.8 ORY46705.1 - 7.1e-17 61.3 0.1 1e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY46705.1 - 6.6e-06 26.1 4.0 1.1e-05 25.5 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 ORY47085.1 - 0.00015 21.6 1.0 0.00055 19.8 1.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORY47085.1 - 0.0055 16.5 2.1 0.11 12.4 2.1 2.4 1 1 0 1 1 1 1 F-box domain DUF974 PF06159.13 ORY47086.1 - 3.9e-62 210.3 0.0 5.6e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) PAS_9 PF13426.7 ORY47087.1 - 1.8e-26 92.4 0.0 9.2e-16 58.0 0.0 3.3 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 ORY47087.1 - 1.8e-21 76.2 0.0 7.2e-11 42.2 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 ORY47087.1 - 2.6e-21 75.7 0.0 1.3e-07 31.6 0.0 4.3 3 1 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ORY47087.1 - 8.5e-13 48.4 0.1 3.8e-07 30.2 0.0 3.4 3 0 0 3 3 3 2 PAS domain GATA PF00320.27 ORY47087.1 - 9.8e-13 47.5 5.5 2.1e-12 46.4 5.5 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 ORY47087.1 - 9.5e-09 35.5 0.0 0.012 15.9 0.0 4.0 4 1 0 4 4 4 3 PAS fold PAS_2 PF08446.11 ORY47087.1 - 0.0007 20.2 0.0 0.84 10.3 0.0 3.2 3 0 0 3 3 3 1 PAS fold Glyco_hydro_88 PF07470.13 ORY47088.1 - 6.3e-18 65.0 0.6 8.6e-18 64.5 0.6 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Bac_rhamnosid6H PF17389.2 ORY47088.1 - 0.021 14.1 1.8 0.04 13.2 1.8 1.5 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 2OG-FeII_Oxy_2 PF13532.6 ORY47090.1 - 9.5e-14 52.0 0.0 1.7e-13 51.2 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ORY47091.1 - 4.1e-27 95.0 76.1 2.8e-16 59.4 40.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.18 ORY47092.1 - 0.0023 17.4 2.1 0.037 13.4 0.2 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_26 PF02156.15 ORY47092.1 - 0.02 14.3 0.4 0.03 13.8 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 ANAPC4_WD40 PF12894.7 ORY47093.1 - 0.0022 18.2 0.0 0.0063 16.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY47093.1 - 0.0073 15.3 0.0 0.049 12.6 0.0 2.0 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 ORY47093.1 - 0.047 13.5 0.5 0.072 12.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4533 PF15047.6 ORY47093.1 - 0.18 11.4 0.5 0.42 10.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF16 PF01519.16 ORY47093.1 - 0.62 10.6 2.3 2.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 ORY47093.1 - 7.6 6.6 6.1 0.54 10.3 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) QCR10 PF09796.9 ORY47094.1 - 3e-21 75.2 0.2 3.9e-21 74.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.10 ORY47094.1 - 0.12 12.4 0.3 0.18 11.7 0.3 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein 2OG-FeII_Oxy_2 PF13532.6 ORY47095.1 - 5.9e-25 88.6 0.0 8e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.25 ORY47096.1 - 1.7e-31 109.2 0.0 2.6e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY47096.1 - 2.1e-25 89.6 0.0 5.3e-25 88.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY47096.1 - 0.00016 21.2 0.0 0.0019 17.7 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY47096.1 - 0.023 14.1 0.3 0.17 11.2 0.0 2.4 2 1 1 3 3 3 0 GDP-mannose 4,6 dehydratase KR PF08659.10 ORY47096.1 - 0.13 12.2 1.1 1.1 9.1 0.4 2.6 2 1 0 2 2 2 0 KR domain ADH_N PF08240.12 ORY47097.1 - 2.4e-25 88.5 4.0 4.2e-25 87.7 4.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY47097.1 - 1.6e-21 76.6 0.0 3.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY47097.1 - 0.00012 21.5 0.8 0.00013 21.3 0.1 1.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY47097.1 - 0.0012 18.2 0.2 0.0023 17.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY47097.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F-box-like PF12937.7 ORY47098.1 - 1.5e-06 28.0 0.3 2.9e-06 27.1 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY47098.1 - 4.4e-05 23.2 0.1 0.00013 21.8 0.0 1.9 2 1 0 2 2 2 1 F-box domain Ribosomal_L34 PF00468.17 ORY47100.1 - 7.1e-18 64.3 7.0 1.1e-17 63.7 7.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 ADH_N PF08240.12 ORY47101.1 - 2.4e-25 88.5 4.0 4.2e-25 87.7 4.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY47101.1 - 1.6e-21 76.6 0.0 3.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY47101.1 - 0.00012 21.5 0.8 0.00013 21.3 0.1 1.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY47101.1 - 0.0012 18.2 0.2 0.0023 17.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY47101.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Tho1_MOS11_C PF18592.1 ORY47102.1 - 0.059 13.2 1.0 0.092 12.6 1.0 1.2 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain Pyr_redox_2 PF07992.14 ORY47103.1 - 4.7e-15 55.6 0.0 9.6e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY47103.1 - 3.7e-06 26.4 0.6 0.0015 17.9 0.0 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY47103.1 - 5.2e-05 23.0 0.7 0.11 12.1 0.6 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY47103.1 - 0.015 14.1 0.5 0.03 13.2 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Malic_M PF03949.15 ORY47103.1 - 0.042 13.1 0.1 0.091 12.0 0.1 1.5 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.27 ORY47103.1 - 0.14 12.8 1.2 19 5.9 0.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY47103.1 - 0.15 12.3 0.6 0.41 10.9 0.6 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ABC_membrane_2 PF06472.15 ORY47182.1 - 5.4e-94 314.6 1.3 7.9e-94 314.0 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY47182.1 - 2.9e-17 63.5 0.0 7.2e-17 62.2 0.0 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 ORY47182.1 - 0.0014 18.5 0.0 0.0041 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY47182.1 - 0.0028 18.0 0.0 0.0064 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ORY47182.1 - 0.012 15.4 0.0 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 ORY47182.1 - 0.013 16.0 0.8 0.029 14.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORY47182.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ORY47182.1 - 0.014 15.1 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 ORY47182.1 - 0.016 14.7 0.0 0.23 10.8 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain SbmA_BacA PF05992.12 ORY47182.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 SbmA/BacA-like family Sigma54_activ_2 PF14532.6 ORY47182.1 - 0.03 14.4 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 ORY47182.1 - 0.039 14.5 0.0 0.086 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY47182.1 - 0.042 13.6 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 ORY47182.1 - 0.071 12.6 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 ORY47182.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3584 PF12128.8 ORY47182.1 - 0.12 9.8 0.1 0.2 9.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_5 PF07728.14 ORY47182.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 ORY47182.1 - 0.18 10.8 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 ORY47182.1 - 0.2 11.6 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain NmrA PF05368.13 ORY47183.1 - 4.7e-24 85.2 0.2 1.1e-22 80.8 0.0 2.3 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 ORY47183.1 - 7.1e-10 39.1 0.0 1.3e-09 38.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Npa1 PF11707.8 ORY47184.1 - 4e-61 207.3 0.2 5.4e-59 200.3 0.0 3.2 3 0 0 3 3 3 2 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 ORY47184.1 - 4e-50 170.2 0.4 1.8e-49 168.1 0.4 2.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Creb_binding PF09030.10 ORY47184.1 - 0.13 12.9 0.1 21 5.9 0.0 3.4 3 0 0 3 3 3 0 Creb binding NmrA PF05368.13 ORY47185.1 - 8.7e-23 81.1 0.0 1.1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY47185.1 - 1e-07 32.1 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY47185.1 - 0.033 13.2 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORY47185.1 - 0.085 13.3 0.1 0.18 12.2 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.25 ORY47186.1 - 1.6e-09 38.0 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 ORY47186.1 - 9.5e-09 36.0 0.0 1.3e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY47186.1 - 0.00096 19.5 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY47186.1 - 0.0037 17.2 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY47186.1 - 0.0049 16.6 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY47186.1 - 0.0053 16.9 0.0 0.0062 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HAD_2 PF13419.6 ORY47187.1 - 1e-09 38.7 0.0 1.4e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY47187.1 - 4e-09 37.1 0.0 3.8e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY47187.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like RNase_P_p30 PF01876.16 ORY47188.1 - 2.2e-24 86.1 0.0 2.1e-23 82.9 0.0 2.0 1 1 0 1 1 1 1 RNase P subunit p30 rRNA_proc-arch PF13234.6 ORY47189.1 - 3.3e-91 306.0 0.0 7.2e-91 304.9 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 ORY47189.1 - 9.4e-53 178.2 0.4 2.3e-52 176.9 0.4 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 ORY47189.1 - 3.8e-18 65.9 0.0 1.2e-17 64.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY47189.1 - 4e-07 30.3 0.0 1.5e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY47189.1 - 0.0006 19.9 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORY47189.1 - 0.042 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 ORY47189.1 - 0.079 13.2 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY47189.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 KaiC DUF1508 PF07411.12 ORY47189.1 - 0.17 11.7 0.2 0.43 10.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) ENTH PF01417.20 ORY47190.1 - 2.1e-30 105.4 0.1 3.8e-30 104.5 0.1 1.4 1 0 0 1 1 1 1 ENTH domain Lactococcin_972 PF09683.10 ORY47191.1 - 0.055 14.0 0.3 0.25 11.9 0.3 2.2 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) Peptidase_M28 PF04389.17 ORY47192.1 - 8.2e-24 84.4 0.0 1.2e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY47192.1 - 2.8e-06 27.2 0.0 5.8e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 BaxI_1 PF12811.7 ORY47192.1 - 0.24 10.9 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Abhydrolase_2 PF02230.16 ORY47193.1 - 2.3e-46 158.4 0.0 2.5e-46 158.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 ORY47193.1 - 1.5e-07 32.2 0.1 1.8e-07 32.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY47193.1 - 3e-07 30.0 0.1 0.0051 16.1 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.20 ORY47193.1 - 0.00026 20.7 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase FSH1 PF03959.13 ORY47193.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 ORY47193.1 - 0.0018 17.9 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORY47193.1 - 0.0026 17.7 0.0 0.0049 16.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY47193.1 - 0.003 17.0 0.2 0.26 10.7 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.14 ORY47193.1 - 0.033 13.5 0.0 0.45 9.8 0.0 2.1 1 1 1 2 2 2 0 Secretory lipase AXE1 PF05448.12 ORY47193.1 - 0.047 12.3 0.1 0.088 11.5 0.1 1.3 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 ORY47193.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold 4HBT PF03061.22 ORY47194.1 - 8.1e-07 29.3 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily UQ_con PF00179.26 ORY47197.1 - 1.5e-47 160.8 0.0 1.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY47197.1 - 0.00013 21.6 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY47197.1 - 0.014 15.2 0.1 0.031 14.1 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 ORY47197.1 - 0.065 13.5 0.4 0.1 12.9 0.4 1.5 1 1 0 1 1 1 0 RWD domain ECH_1 PF00378.20 ORY47199.1 - 7.6e-40 136.8 0.0 9.9e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY47199.1 - 5e-20 72.3 0.0 2.3e-19 70.1 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Malate_synthase PF01274.22 ORY47200.1 - 6.3e-36 123.7 0.0 6.9e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Malate synthase SOG2 PF10428.9 ORY47568.1 - 0.53 9.4 12.9 0.64 9.1 12.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein GP46 PF07409.12 ORY47569.1 - 0.006 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Phage protein GP46 WD40 PF00400.32 ORY47570.1 - 4.1e-20 71.7 4.0 0.00045 21.0 0.0 7.3 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY47570.1 - 1.6e-12 47.6 0.0 0.00023 21.4 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY47570.1 - 4.4e-05 23.3 0.3 0.067 13.1 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat BING4CT PF08149.11 ORY47570.1 - 0.0044 16.8 0.0 0.02 14.7 0.0 2.1 2 0 0 2 2 2 1 BING4CT (NUC141) domain eIF2A PF08662.11 ORY47570.1 - 0.01 15.7 0.1 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY47570.1 - 0.014 14.4 0.2 3.2 6.6 0.0 3.5 4 1 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY47570.1 - 0.018 14.4 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 WD40-like domain DUF2914 PF11141.8 ORY47570.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) Zn_clus PF00172.18 ORY47571.1 - 4.8e-07 29.8 10.2 7.4e-07 29.2 10.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.9 ORY47572.1 - 2.9 7.0 9.1 3.3 6.8 9.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RRM_1 PF00076.22 ORY47574.1 - 7.3e-22 77.0 0.0 8.9e-15 54.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY47574.1 - 0.027 14.1 0.0 0.078 12.6 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 ORY47574.1 - 0.13 12.3 0.0 17 5.5 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain APG6_N PF17675.1 ORY47575.1 - 0.93 10.0 10.8 1.7 9.2 10.8 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 ORY47575.1 - 5.3 7.2 14.6 9.2 6.5 14.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 U79_P34 PF03064.16 ORY47575.1 - 8.6 5.6 10.0 15 4.8 10.0 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Zn_clus PF00172.18 ORY47576.1 - 0.12 12.5 9.6 0.28 11.3 9.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY47577.1 - 0.001 19.1 10.4 0.0017 18.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY47579.1 - 0.12 12.5 11.6 0.056 13.6 9.4 1.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RGCC PF15151.6 ORY47580.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family ABM PF03992.16 ORY47583.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase WW PF00397.26 ORY47583.1 - 2.4e-09 37.1 0.0 4.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 WW domain FKBP_C PF00254.28 ORY47584.1 - 2.2e-34 117.6 0.0 3.1e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ArsA_HSP20 PF17886.1 ORY47586.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.3 1 1 0 1 1 1 0 HSP20-like domain found in ArsA Peroxin-13_N PF04088.13 ORY47587.1 - 4.4e-47 160.0 0.0 6.1e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 ORY47587.1 - 8.5e-12 44.5 0.0 1.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY47587.1 - 3.1e-11 42.9 0.1 5.3e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY47587.1 - 3.6e-11 42.6 0.0 6.4e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HlyIII PF03006.20 ORY47590.1 - 2.2e-48 164.9 12.5 3e-48 164.5 12.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Apolipoprotein PF01442.18 ORY47590.1 - 0.14 12.0 8.1 0.038 13.9 1.5 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain zf-C3HC4_2 PF13923.6 ORY48006.1 - 4.1e-07 29.7 8.4 1.1e-06 28.3 8.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY48006.1 - 1.5e-06 27.9 8.0 5.1e-06 26.3 8.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY48006.1 - 6.7e-06 25.9 7.7 1.9e-05 24.4 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY48006.1 - 1.3e-05 25.4 9.0 1.3e-05 25.4 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-TRAF PF02176.18 ORY48006.1 - 0.00015 22.4 11.5 0.0036 17.9 1.9 3.7 3 2 2 5 5 5 2 TRAF-type zinc finger zf-rbx1 PF12678.7 ORY48006.1 - 0.0044 17.3 8.2 0.0044 17.3 8.2 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain U-box PF04564.15 ORY48006.1 - 0.0096 16.1 0.2 5.7 7.2 0.0 2.7 3 0 0 3 3 3 1 U-box domain zf-P11 PF03854.14 ORY48006.1 - 0.019 14.6 2.1 0.019 14.6 2.1 2.5 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_5 PF14634.6 ORY48006.1 - 0.022 14.7 8.3 0.1 12.6 8.3 2.2 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_14 PF17978.1 ORY48006.1 - 0.038 14.4 5.5 0.36 11.3 5.5 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain LIM PF00412.22 ORY48006.1 - 0.044 14.0 1.1 0.044 14.0 1.1 2.6 3 0 0 3 3 3 0 LIM domain Tup_N PF08581.10 ORY48006.1 - 0.07 13.4 0.2 0.53 10.6 0.2 2.0 2 0 0 2 2 2 0 Tup N-terminal zf-RING_10 PF16685.5 ORY48006.1 - 0.088 13.0 8.2 0.23 11.6 8.2 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 ORY48006.1 - 0.12 12.6 6.7 0.53 10.5 6.7 2.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1644 PF07800.12 ORY48006.1 - 0.82 9.7 13.0 0.044 13.8 6.0 2.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1644) Sina PF03145.16 ORY48006.1 - 5 7.0 15.7 0.26 11.2 1.1 3.2 1 1 2 3 3 3 0 Seven in absentia protein family SicP-binding PF09119.10 ORY48007.1 - 0.038 14.0 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 SicP binding HALZ PF02183.18 ORY48008.1 - 0.055 13.7 0.9 5.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rep_fac_C PF08542.11 ORY48009.1 - 2.3e-21 76.0 0.0 5.6e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ORY48009.1 - 2e-17 63.9 0.0 3.4e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORY48009.1 - 1e-13 51.4 0.0 1.6e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ORY48009.1 - 2.6e-07 30.8 0.0 9.6e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 ORY48009.1 - 1.2e-06 28.4 0.1 7.4e-05 22.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_assoc_2 PF16193.5 ORY48009.1 - 1.8e-06 28.2 0.1 1.4e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 ORY48009.1 - 8.5e-06 25.7 0.0 3.8e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY48009.1 - 5.5e-05 23.6 0.0 0.00053 20.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY48009.1 - 0.0002 21.6 0.2 0.049 13.9 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY48009.1 - 0.00043 20.6 0.2 0.054 13.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 ORY48009.1 - 0.0005 19.9 0.0 0.00078 19.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 ORY48009.1 - 0.0016 17.7 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY48009.1 - 0.0019 18.0 0.0 0.005 16.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY48009.1 - 0.002 18.1 0.2 0.012 15.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 ORY48009.1 - 0.0033 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 ORY48009.1 - 0.0033 16.9 0.0 0.73 9.2 0.0 2.7 3 0 0 3 3 3 1 Bacterial TniB protein AAA_3 PF07726.11 ORY48009.1 - 0.0039 17.1 0.0 0.0096 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 ORY48009.1 - 0.0064 16.3 0.1 0.036 13.8 0.0 2.0 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY48009.1 - 0.016 15.2 0.0 0.95 9.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 ORY48009.1 - 0.035 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 ORY48009.1 - 0.068 13.7 0.0 0.2 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORY48009.1 - 0.076 12.4 0.0 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ORY48009.1 - 0.081 12.7 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein T2SSE PF00437.20 ORY48009.1 - 0.091 11.8 0.0 0.48 9.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein DNA_pol3_delta PF06144.13 ORY48009.1 - 0.098 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PIF1 PF05970.14 ORY48009.1 - 0.12 11.5 0.0 2 7.5 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase Pkinase PF00069.25 ORY48010.1 - 1.9e-40 138.9 0.0 1.2e-18 67.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48010.1 - 1.8e-12 47.1 0.0 1.1e-09 37.9 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase CENP-B_dimeris PF09026.10 ORY48010.1 - 0.0082 16.5 3.0 0.15 12.4 3.6 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain APH PF01636.23 ORY48010.1 - 0.03 14.2 0.0 0.074 13.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RTA1 PF04479.13 ORY48012.1 - 3.9e-53 180.1 9.3 3.9e-53 180.1 9.3 1.8 1 1 1 2 2 2 1 RTA1 like protein Poxvirus_B22R_C PF13168.6 ORY48012.1 - 0.25 10.8 1.5 0.4 10.1 1.5 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Vma12 PF11712.8 ORY48012.1 - 0.31 11.1 0.9 0.65 10.1 0.9 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4577 PF15145.6 ORY48012.1 - 3 7.9 4.2 1.6 8.8 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4577) RTA1 PF04479.13 ORY48013.1 - 2.7e-54 183.9 6.4 2.7e-54 183.9 6.4 2.0 1 1 1 2 2 2 2 RTA1 like protein DUF4234 PF14018.6 ORY48013.1 - 0.013 15.6 0.9 0.034 14.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF5134 PF17197.4 ORY48013.1 - 0.054 13.4 5.0 0.17 11.8 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5134) RTA1 PF04479.13 ORY48014.1 - 4.7e-52 176.6 7.0 4.7e-52 176.6 7.0 1.8 1 1 1 2 2 2 1 RTA1 like protein RTA1 PF04479.13 ORY48015.1 - 7.4e-53 179.2 9.1 7.4e-53 179.2 9.1 1.8 1 1 1 2 2 2 1 RTA1 like protein Poxvirus_B22R_C PF13168.6 ORY48015.1 - 0.24 10.8 1.5 0.39 10.2 1.5 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Vma12 PF11712.8 ORY48015.1 - 0.3 11.2 0.9 0.63 10.1 0.9 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4577 PF15145.6 ORY48015.1 - 3 7.9 4.2 1.5 8.8 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4577) Bromodomain PF00439.25 ORY48408.1 - 2e-17 63.0 0.1 6.6e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 Bromodomain Peptidase_M1 PF01433.20 ORY48408.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY48408.1 - 0.009 16.2 0.0 0.093 12.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF1899 PF08953.11 ORY48409.1 - 2.3e-28 97.9 0.0 4e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 ORY48409.1 - 1.1e-21 76.4 1.4 3.4e-20 71.7 0.1 2.6 2 0 0 2 2 2 1 Type of WD40 repeat ANAPC4_WD40 PF12894.7 ORY48409.1 - 4.2e-08 33.4 0.0 0.00095 19.4 0.1 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY48409.1 - 5.9e-06 26.9 6.4 2.9 8.9 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat MAD PF05557.13 ORY48409.1 - 0.011 14.1 0.2 0.015 13.7 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TonB_N PF16031.5 ORY48409.1 - 0.015 15.8 25.7 0.031 14.8 25.7 1.4 1 0 0 1 1 1 0 TonB polyproline region SOG2 PF10428.9 ORY48409.1 - 3.7 6.6 6.5 5 6.2 6.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TALPID3 PF15324.6 ORY48409.1 - 9.3 3.8 20.0 12 3.4 20.0 1.1 1 0 0 1 1 1 0 Hedgehog signalling target Fungal_trans PF04082.18 ORY48410.1 - 2.6e-19 69.3 0.0 3.1e-18 65.8 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY48410.1 - 5.9e-07 29.5 8.6 9.9e-07 28.8 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5351 PF17302.2 ORY48410.1 - 0.013 15.6 1.1 0.026 14.7 1.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5351) HTH_IclR PF09339.10 ORY48410.1 - 0.082 12.7 0.2 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 IclR helix-turn-helix domain Mito_fiss_reg PF05308.11 ORY48410.1 - 5.9 6.9 7.5 1.2 9.1 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator XPG_N PF00752.17 ORY48412.1 - 1.2e-29 102.8 0.0 2.3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORY48412.1 - 1.5e-24 86.1 0.0 4.3e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 ORY48412.1 - 0.0017 17.9 0.1 0.0017 17.9 0.1 2.2 2 1 0 2 2 2 1 XPG domain containing DGF-1_C PF11040.8 ORY48412.1 - 0.43 10.6 4.0 1.9 8.5 0.3 3.2 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Aldo_ket_red PF00248.21 ORY48413.1 - 2.8e-30 105.5 0.0 9.3e-20 71.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORY48414.1 - 3.7e-36 124.8 0.0 4.8e-25 88.4 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Glycos_transf_1 PF00534.20 ORY48415.1 - 1.2e-23 83.5 0.0 2.6e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY48415.1 - 4.8e-22 78.8 0.0 7.8e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 ORY48415.1 - 1.1e-13 51.4 0.0 1e-12 48.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_4 PF13439.6 ORY48415.1 - 6.4e-10 39.3 1.4 1.5e-09 38.1 0.0 2.3 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ORY48415.1 - 0.0023 18.3 0.0 0.0062 16.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Rhamno_transf PF11316.8 ORY48415.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase KH_1 PF00013.29 ORY48416.1 - 1.2e-44 150.0 13.9 1.2e-16 60.2 1.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY48416.1 - 9.9e-15 54.1 9.3 9.7e-06 25.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY48416.1 - 1.4e-05 24.9 2.8 0.38 10.7 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY48416.1 - 0.02 15.0 9.7 7.8 6.7 1.2 3.6 3 1 0 3 3 3 0 NusA-like KH domain GRP PF07172.11 ORY48416.1 - 0.053 14.2 19.0 0.094 13.4 19.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family SNF2_N PF00176.23 ORY48417.1 - 6.2e-58 196.2 0.0 1.2e-56 191.9 0.0 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY48417.1 - 6.6e-17 61.8 0.0 1.4e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY48417.1 - 1e-06 28.2 0.0 3.3e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORY48417.1 - 1.5e-06 28.3 0.0 1.9e-05 24.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY48417.1 - 0.00026 20.8 0.0 0.00058 19.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.29 ORY48417.1 - 0.00053 19.8 24.2 0.0032 17.3 6.5 3.1 3 0 0 3 3 3 2 PHD-finger DUF2642 PF10842.8 ORY48417.1 - 0.067 13.1 0.0 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) C1_1 PF00130.22 ORY48417.1 - 0.79 9.7 21.4 0.069 13.0 4.1 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DIOX_N PF14226.6 ORY48419.1 - 5.3e-23 82.0 0.0 9.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY48419.1 - 3.3e-14 53.2 0.0 6.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cwf_Cwc_15 PF04889.12 ORY48420.1 - 0.042 13.6 14.8 0.014 15.1 10.4 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Rubi_NSP_C PF12601.8 ORY48420.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein NIF PF03031.18 ORY48421.1 - 8.9e-08 32.0 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CSTF2_hinge PF14327.6 ORY48422.1 - 1e-31 109.2 1.9 1e-31 109.2 1.9 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 ORY48422.1 - 1.2e-23 82.7 0.0 1.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 ORY48422.1 - 3e-13 49.1 5.9 3e-13 49.1 5.9 2.2 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 ORY48422.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif Peptidase_M16_C PF05193.21 ORY48423.1 - 2.3e-40 138.6 0.0 3.7e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY48423.1 - 1.2e-35 122.7 0.0 2.1e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ribosomal_S17 PF00366.20 ORY48424.1 - 9.7e-20 70.4 1.4 1.3e-19 70.0 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 NADH_Oxid_Nqo15 PF11497.8 ORY48424.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 LNP1 PF15419.6 ORY48424.1 - 0.5 10.6 4.2 1 9.6 4.2 1.7 1 1 0 1 1 1 0 Leukemia NUP98 fusion partner 1 BTB PF00651.31 ORY48425.1 - 0.063 13.5 0.1 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain DNA_topoisoIV PF00521.20 ORY48818.1 - 9.7e-119 397.0 0.1 6.8e-118 394.2 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ORY48818.1 - 1.6e-52 177.1 0.4 1.6e-52 177.1 0.4 2.0 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ORY48818.1 - 6.3e-25 87.6 0.8 6.3e-25 87.6 0.8 1.7 2 0 0 2 2 2 1 DNA gyrase B HATPase_c PF02518.26 ORY48818.1 - 1.7e-13 51.0 0.1 4.7e-13 49.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ORY48818.1 - 1e-05 25.7 0.0 3.6e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DUF3275 PF11679.8 ORY48818.1 - 5 7.1 7.4 9.6 6.1 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) SOG2 PF10428.9 ORY48819.1 - 0.24 10.6 15.9 0.33 10.1 15.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SWIM PF04434.17 ORY48820.1 - 0.00046 19.8 0.3 0.00091 18.8 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger DUF3287 PF11690.8 ORY48820.1 - 0.13 12.0 1.2 15 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Syntaxin_2 PF14523.6 ORY48821.1 - 0.12 12.8 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 Syntaxin-like protein EutQ PF06249.12 ORY48822.1 - 7.3e-10 38.8 0.0 8.7e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 ORY48822.1 - 0.0019 17.9 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ORY48822.1 - 0.021 14.5 0.1 0.033 13.9 0.1 1.3 1 0 0 1 1 1 0 Cupin domain Piwi PF02171.17 ORY48823.1 - 3.9e-80 269.3 0.0 5e-80 269.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 ORY48823.1 - 4.5e-12 45.4 0.0 1.4e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 ORY48823.1 - 1.4e-11 44.5 0.0 4e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 ORY48823.1 - 3.5e-05 24.0 0.0 8.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 ORY48823.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 PAZ domain ArgoN PF16486.5 ORY48823.1 - 0.13 12.8 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of argonaute Transp_cyt_pur PF02133.15 ORY48824.1 - 7.9e-38 130.4 39.4 1.2e-37 129.7 39.4 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Arteri_Gl PF00951.18 ORY48824.1 - 0.1 12.4 3.1 1.6 8.5 0.4 2.8 2 0 0 2 2 2 0 Arterivirus GL envelope glycoprotein Hol_Tox PF16935.5 ORY48824.1 - 9 6.4 6.4 21 5.2 0.5 3.3 3 0 0 3 3 3 0 Putative Holin-like Toxin (Hol-Tox) dCMP_cyt_deam_1 PF00383.23 ORY48825.1 - 7e-18 64.4 0.1 9.1e-18 64.0 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY48825.1 - 1.4e-16 60.5 0.0 2.2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 ORY48825.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 ORY48825.1 - 0.0039 17.3 1.8 0.22 11.6 1.0 2.2 1 1 1 2 2 2 1 Bd3614-like deaminase NAD1 PF18778.1 ORY48825.1 - 0.016 15.3 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 ORY48825.1 - 0.023 14.7 0.0 0.058 13.4 0.0 1.6 2 0 0 2 2 2 0 APOBEC2 NAD2 PF18782.1 ORY48825.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 ORY48825.1 - 0.059 13.3 0.0 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC3 PF18771.1 ORY48825.1 - 0.12 12.4 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 DSPc PF00782.20 ORY48828.1 - 7.8e-06 25.7 0.0 2.3e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 ORY48828.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 ORY48828.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MFAP1 PF06991.11 ORY48829.1 - 7.8e-66 222.0 16.3 7.8e-66 222.0 16.3 3.2 2 1 2 4 4 4 1 Microfibril-associated/Pre-mRNA processing zf-CCHC PF00098.23 ORY48829.1 - 0.15 12.2 1.6 0.33 11.1 1.6 1.6 1 1 0 1 1 1 0 Zinc knuckle LSM PF01423.22 ORY48830.1 - 3.3e-05 23.5 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 ORY48830.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain Ribosomal_S14 PF00253.21 ORY48831.1 - 5.3e-13 48.5 4.7 5.7e-13 48.4 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e KKLCAg1 PF15204.6 ORY48832.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Ribosomal_S8e PF01201.22 ORY48833.1 - 8.8e-57 191.1 1.0 1.1e-56 190.8 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Cylicin_N PF15241.6 ORY48833.1 - 0.98 9.6 4.2 0.18 11.9 0.4 1.7 2 0 0 2 2 2 0 Cylicin N-terminus DUF4778 PF16008.5 ORY48834.1 - 0.58 10.2 8.3 0.91 9.5 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF1365 PF07103.11 ORY48835.1 - 5.1e-68 229.3 0.0 6.6e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Malic_M PF03949.15 ORY48835.1 - 0.24 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Ras PF00071.22 ORY48836.1 - 8.1e-39 132.8 0.0 8.5e-36 123.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY48836.1 - 5.2e-30 104.1 0.0 8.2e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY48836.1 - 8.7e-11 41.6 0.0 2.8e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY48836.1 - 0.0012 18.4 0.0 0.021 14.3 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY48836.1 - 0.0017 18.5 0.0 0.0094 16.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY48836.1 - 0.0091 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 ORY48836.1 - 0.035 13.8 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ORY48836.1 - 0.036 14.3 0.0 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY48836.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 ORY48836.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 ORY48836.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Bac_luciferase PF00296.20 ORY48837.1 - 3.1e-68 230.5 0.4 4.3e-68 230.0 0.4 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2371 PF10177.9 ORY49285.1 - 0.0049 17.0 0.1 0.0059 16.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2371) DUF4383 PF14325.6 ORY49285.1 - 0.033 14.5 0.2 0.038 14.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) SSP160 PF06933.11 ORY49285.1 - 1.3 7.1 21.0 1.6 6.8 21.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RAP1 PF07218.11 ORY49285.1 - 2.7 6.2 6.3 2.7 6.1 6.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CcmH PF03918.14 ORY49286.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Cofilin_ADF PF00241.20 ORY49288.1 - 2.2e-26 92.0 0.1 2.5e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1996 PF09362.10 ORY49289.1 - 1.1e-71 241.5 0.1 1.6e-71 241.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Dehydrin PF00257.19 ORY49289.1 - 0.13 12.8 16.3 0.21 12.2 16.3 1.3 1 0 0 1 1 1 0 Dehydrin Syntaxin-6_N PF09177.11 ORY49290.1 - 9.9e-21 74.2 0.8 6.8e-20 71.5 0.0 2.2 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 ORY49290.1 - 1.3e-11 44.3 0.7 3.6e-11 42.9 0.7 1.8 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 ORY49290.1 - 1.8e-05 24.6 1.2 3.6e-05 23.6 1.3 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 FliD_C PF07195.12 ORY49290.1 - 0.0042 16.5 0.2 0.0048 16.4 0.2 1.3 1 1 0 1 1 1 1 Flagellar hook-associated protein 2 C-terminus DUF2207 PF09972.9 ORY49290.1 - 0.031 13.0 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FliJ PF02050.16 ORY49290.1 - 0.045 14.0 2.0 0.93 9.7 0.0 2.5 2 1 1 3 3 3 0 Flagellar FliJ protein TMCO5 PF14992.6 ORY49290.1 - 0.087 12.4 0.9 0.45 10.1 0.2 2.1 2 1 0 2 2 2 0 TMCO5 family Orf78 PF06024.12 ORY49290.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Orf78 (ac78) Pox_EPC_I2-L1 PF12575.8 ORY49290.1 - 0.49 10.7 2.7 0.35 11.1 0.7 1.8 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 FlaC_arch PF05377.11 ORY49290.1 - 0.79 10.2 5.9 13 6.3 0.2 3.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) YtxH PF12732.7 ORY49291.1 - 0.17 12.4 4.4 14 6.3 0.1 3.1 3 0 0 3 3 3 0 YtxH-like protein ABC_membrane PF00664.23 ORY49292.1 - 4.2e-106 354.6 21.0 6.8e-55 186.6 7.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY49292.1 - 6e-67 224.4 0.0 4.4e-34 117.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY49292.1 - 1.5e-16 60.5 0.9 1.3e-05 24.8 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY49292.1 - 6.5e-08 32.2 0.5 0.0051 16.5 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORY49292.1 - 2.3e-07 30.0 3.3 0.0086 14.9 0.0 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ORY49292.1 - 1e-06 28.8 0.0 0.018 14.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY49292.1 - 1.6e-06 28.7 0.6 0.2 12.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 ORY49292.1 - 2.5e-06 27.5 0.0 0.076 12.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY49292.1 - 4.9e-06 26.9 1.9 0.0059 16.9 0.0 3.7 2 2 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY49292.1 - 3e-05 23.4 0.2 0.15 11.3 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_16 PF13191.6 ORY49292.1 - 3.7e-05 24.2 6.9 0.0064 16.9 0.1 3.7 3 1 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 ORY49292.1 - 7e-05 22.7 0.4 0.62 9.7 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_30 PF13604.6 ORY49292.1 - 0.00019 21.2 5.6 0.29 10.9 0.0 4.2 4 2 0 4 4 3 2 AAA domain AAA_25 PF13481.6 ORY49292.1 - 0.00037 20.1 0.1 1.3 8.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 ORY49292.1 - 0.0019 18.6 3.2 0.16 12.4 0.1 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY49292.1 - 0.003 17.1 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 ORY49292.1 - 0.0046 16.9 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 ORY49292.1 - 0.0047 16.9 0.2 1 9.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ORY49292.1 - 0.0059 15.8 0.4 0.24 10.6 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain RNA_helicase PF00910.22 ORY49292.1 - 0.0088 16.4 0.1 1.9 8.9 0.0 3.4 3 0 0 3 3 3 1 RNA helicase SbcCD_C PF13558.6 ORY49292.1 - 0.0092 16.2 3.2 1.2 9.4 0.3 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 ORY49292.1 - 0.012 16.2 0.1 1.2 9.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY49292.1 - 0.021 15.0 0.3 1.8 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY49292.1 - 0.036 14.2 1.5 1.5 9.0 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Terminase_1 PF03354.15 ORY49292.1 - 0.042 12.4 0.1 0.09 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage Terminase AAA_28 PF13521.6 ORY49292.1 - 0.051 13.8 3.4 1.6 8.9 0.0 3.4 4 0 0 4 4 2 0 AAA domain G-alpha PF00503.20 ORY49292.1 - 0.055 12.6 0.1 6.8 5.7 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 ORY49292.1 - 0.058 13.3 0.4 1.1 9.1 0.0 2.8 3 0 0 3 3 2 0 NTPase PRK PF00485.18 ORY49292.1 - 0.073 12.8 0.0 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 ORY49292.1 - 0.073 12.8 0.1 8 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORY49292.1 - 0.079 13.0 0.7 28 4.7 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_14 PF13173.6 ORY49292.1 - 0.11 12.5 0.1 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 ORY49292.1 - 0.11 12.2 0.1 17 5.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 ORY49292.1 - 0.13 12.5 0.1 17 5.8 0.1 3.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY49292.1 - 0.52 10.2 1.7 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 ORY49292.1 - 1.7 9.1 4.7 34 4.8 0.0 3.7 3 1 0 3 3 3 0 AAA domain ABC_membrane PF00664.23 ORY49293.1 - 2.8e-108 361.7 30.5 4e-57 194.0 15.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY49293.1 - 7e-67 224.2 0.0 4.8e-34 117.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY49293.1 - 9.6e-15 54.6 3.6 0.00012 21.6 0.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY49293.1 - 7.8e-08 31.9 0.5 0.0054 16.4 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 ORY49293.1 - 2e-07 30.2 2.7 0.0096 14.8 0.0 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 ORY49293.1 - 1.3e-06 28.5 0.0 0.019 14.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY49293.1 - 3.7e-06 27.6 0.4 0.22 12.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 ORY49293.1 - 4.5e-06 26.7 0.0 0.083 12.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY49293.1 - 1.5e-05 25.4 5.7 0.011 16.1 0.1 4.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 ORY49293.1 - 4.4e-05 23.8 5.5 0.0068 16.7 0.0 4.1 3 2 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 ORY49293.1 - 9.9e-05 21.7 0.0 0.17 11.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 ORY49293.1 - 0.00011 22.0 4.9 0.31 10.8 0.0 4.3 4 2 0 4 4 4 2 AAA domain AAA_15 PF13175.6 ORY49293.1 - 0.00017 21.5 0.2 0.64 9.7 0.0 2.5 3 0 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 ORY49293.1 - 0.00041 20.0 0.0 1.4 8.4 0.0 3.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORY49293.1 - 0.002 18.3 2.7 1.3 9.3 0.3 4.5 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 ORY49293.1 - 0.0033 17.0 0.0 2.5 7.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 ORY49293.1 - 0.0045 17.0 0.2 1.1 9.3 0.0 3.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY49293.1 - 0.0046 17.4 5.2 0.16 12.4 0.2 4.2 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY49293.1 - 0.005 16.8 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 ORY49293.1 - 0.0075 15.5 0.3 0.24 10.5 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain AAA_28 PF13521.6 ORY49293.1 - 0.01 16.1 0.1 1.8 8.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain RhaA PF06134.11 ORY49293.1 - 0.014 14.6 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) AAA_18 PF13238.6 ORY49293.1 - 0.014 16.0 0.2 1.4 9.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 ORY49293.1 - 0.022 14.9 0.3 1.9 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORY49293.1 - 0.04 13.8 0.2 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 ORY49293.1 - 0.041 14.0 1.6 1.6 8.9 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase G-alpha PF00503.20 ORY49293.1 - 0.06 12.5 0.0 7.3 5.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 ORY49293.1 - 0.061 13.0 0.1 8.6 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORY49293.1 - 0.092 12.5 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Terminase_1 PF03354.15 ORY49293.1 - 0.093 11.3 0.1 0.19 10.2 0.1 1.4 1 0 0 1 1 1 0 Phage Terminase DUF87 PF01935.17 ORY49293.1 - 0.097 12.7 0.2 30 4.6 0.0 2.9 2 0 0 2 2 2 0 Helicase HerA, central domain PUL PF08324.11 ORY49293.1 - 0.1 11.8 1.3 0.25 10.6 1.3 1.5 1 0 0 1 1 1 0 PUL domain AAA_14 PF13173.6 ORY49293.1 - 0.12 12.4 0.7 1.3 9.0 0.0 3.0 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 ORY49293.1 - 0.15 11.8 0.1 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2207 PF09972.9 ORY49293.1 - 0.15 10.8 11.4 2 7.1 0.0 4.1 5 0 0 5 5 5 0 Predicted membrane protein (DUF2207) AAA_19 PF13245.6 ORY49293.1 - 0.16 12.3 0.6 18 5.7 0.1 3.2 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 ORY49293.1 - 0.16 12.4 2.2 2 8.8 0.0 3.4 3 0 0 3 3 2 0 RNA helicase AAA_17 PF13207.6 ORY49293.1 - 0.33 11.4 1.9 37 4.8 0.0 3.5 3 0 0 3 3 2 0 AAA domain GIY-YIG PF01541.24 ORY49295.1 - 1.4e-11 44.5 0.0 2.7e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FYDLN_acid PF09538.10 ORY49295.1 - 0.96 10.2 6.6 4 8.2 6.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Methyltransf_16 PF10294.9 ORY49296.1 - 3.3e-07 30.2 0.0 7.3e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_25 PF13649.6 ORY49296.1 - 0.026 15.2 0.0 0.05 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORY49296.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ORY49296.1 - 0.25 11.1 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Macro PF01661.21 ORY49297.1 - 1.8e-25 89.3 0.0 2.8e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Macro domain Peptidase_M49 PF03571.15 ORY49299.1 - 1.2e-216 720.4 0.0 1.9e-216 719.7 0.0 1.3 2 0 0 2 2 2 1 Peptidase family M49 RmlD_sub_bind PF04321.17 ORY49300.1 - 7.3e-52 176.2 0.0 9e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ORY49300.1 - 1.2e-26 93.7 0.0 1.5e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY49300.1 - 2.9e-11 43.4 0.0 1.4e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY49300.1 - 4.6e-08 32.6 0.0 1.2e-06 28.0 0.0 2.1 1 1 1 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY49300.1 - 7e-07 28.7 0.1 0.0004 19.6 0.0 3.1 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY49300.1 - 0.0014 17.6 0.0 0.0053 15.8 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY49300.1 - 0.015 15.2 2.2 0.21 11.5 2.2 2.4 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 ORY49300.1 - 0.026 14.1 1.1 0.12 11.9 0.5 2.3 2 1 0 2 2 2 0 NmrA-like family COX6B PF02297.17 ORY49301.1 - 9.1e-22 77.1 0.5 1.2e-21 76.7 0.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 ORY49301.1 - 0.046 14.0 0.4 0.064 13.6 0.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SAM_2 PF07647.17 ORY49302.1 - 1.1e-08 35.1 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY49302.1 - 3.4e-05 24.2 0.1 9.1e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Apt1 PF10351.9 ORY49724.1 - 0.0067 15.3 7.9 0.0091 14.9 7.9 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain Macoilin PF09726.9 ORY49724.1 - 0.3 9.6 6.6 0.37 9.3 6.6 1.1 1 0 0 1 1 1 0 Macoilin family AJAP1_PANP_C PF15298.6 ORY49724.1 - 1.7 8.9 9.3 3 8.0 9.3 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Peptidase_S64 PF08192.11 ORY49724.1 - 2.5 6.5 7.8 2.9 6.3 7.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 GAS PF13851.6 ORY49725.1 - 0.014 14.8 3.9 0.014 14.8 3.9 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding CorA PF01544.18 ORY49725.1 - 0.82 8.9 10.8 1.2 8.4 10.0 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein YabA PF06156.13 ORY49725.1 - 1.7 9.4 17.3 0.094 13.4 2.6 3.6 1 1 2 3 3 3 0 Initiation control protein YabA CHD5 PF04420.14 ORY49725.1 - 4.4 7.1 8.3 0.64 9.9 2.4 2.3 2 0 0 2 2 2 0 CHD5-like protein V_ATPase_I PF01496.19 ORY49725.1 - 5.2 4.8 10.7 0.92 7.4 6.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family YIF1 PF03878.15 ORY49727.1 - 1.7e-76 256.9 0.0 8.8e-76 254.6 0.0 2.0 2 1 0 2 2 2 1 YIF1 Yip1 PF04893.17 ORY49727.1 - 3.2 7.4 10.5 12 5.6 10.5 1.9 1 1 0 1 1 1 0 Yip1 domain Inj_translocase PF16928.5 ORY49727.1 - 5.4 6.4 7.6 8.6 5.7 7.6 1.2 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome ERCC4 PF02732.15 ORY49728.1 - 7.6e-20 71.7 0.0 1.3e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF2967 PF11179.8 ORY49728.1 - 1.8 6.6 7.6 3.2 5.7 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Sugar_tr PF00083.24 ORY49729.1 - 4.9e-128 427.8 23.8 5.8e-128 427.6 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY49729.1 - 8.4e-17 61.1 43.9 7.9e-11 41.5 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SNARE PF05739.19 ORY49731.1 - 2.3e-07 30.7 0.8 5.9e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 SNARE domain Prominin PF05478.11 ORY49731.1 - 0.06 11.3 1.2 0.061 11.3 0.1 1.5 2 0 0 2 2 2 0 Prominin DUF2207 PF09972.9 ORY49731.1 - 0.2 10.4 0.1 0.26 10.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Spc7 PF08317.11 ORY49731.1 - 0.4 9.5 9.4 1.5 7.6 6.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein YjcZ PF13990.6 ORY49731.1 - 1.1 8.5 6.8 4.2 6.7 2.8 2.0 2 0 0 2 2 2 0 YjcZ-like protein Exonuc_VII_L PF02601.15 ORY49731.1 - 1.6 8.3 6.6 3.5 7.1 6.7 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit RRN3 PF05327.11 ORY49731.1 - 1.9 7.0 5.8 2.1 6.8 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5383 PF17355.2 ORY49731.1 - 4.3 7.7 7.0 2.7e+02 1.9 7.0 2.5 1 1 0 1 1 1 0 Family of unknown function (DUF5383) RicinB_lectin_2 PF14200.6 ORY49732.1 - 0.019 15.7 2.7 2.7 8.8 0.2 3.3 2 1 2 4 4 4 0 Ricin-type beta-trefoil lectin domain-like Sugar_tr PF00083.24 ORY49733.1 - 1.7e-124 416.1 17.9 2e-124 415.9 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY49733.1 - 1.1e-29 103.5 59.5 3.7e-28 98.5 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 ORY49735.1 - 6.6e-40 136.6 0.2 6.6e-40 136.6 0.2 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORY49735.1 - 2.8e-27 96.4 0.0 8.1e-27 94.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORY49735.1 - 7.3e-18 64.8 0.0 0.00051 20.4 0.0 4.7 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ORY49735.1 - 2.8e-06 27.3 0.0 0.007 16.1 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY49735.1 - 0.00098 19.6 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.6 ORY49735.1 - 0.21 11.7 0.0 2.4 8.3 0.0 2.6 3 0 0 3 3 3 0 Papain fold toxin 2 Fer2_BFD PF04324.15 ORY49735.1 - 0.65 10.4 4.7 74 3.8 0.0 4.2 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain DUF726 PF05277.12 ORY49736.1 - 8.1e-62 209.1 0.1 1.3e-61 208.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF2207 PF09972.9 ORY49736.1 - 0.073 11.8 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) adh_short_C2 PF13561.6 ORY49737.1 - 9.1e-44 149.8 0.0 1.4e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY49737.1 - 5.5e-42 143.4 0.0 1e-41 142.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY49737.1 - 5.3e-09 36.2 0.0 9.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 KR domain 4HBT_2 PF13279.6 ORY49738.1 - 4.6e-14 53.0 0.0 6.1e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ORY49738.1 - 2.2e-05 24.7 0.0 3.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Host_attach PF10116.9 ORY49739.1 - 1.1 9.9 6.2 1.9 9.1 4.9 2.0 1 1 1 2 2 2 0 Protein required for attachment to host cells Helitron_like_N PF14214.6 ORY49740.1 - 0.043 14.0 0.5 0.11 12.7 0.5 1.6 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DCP1 PF06058.13 ORY49742.1 - 2.6e-25 88.6 0.0 2.9e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family IGR PF09597.10 ORY49743.1 - 3.4e-14 52.7 0.3 5.1e-14 52.1 0.3 1.2 1 0 0 1 1 1 1 IGR protein motif Lipoprotein_20 PF13942.6 ORY49743.1 - 0.051 13.5 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 YfhG lipoprotein HGTP_anticodon PF03129.20 ORY50183.1 - 1.2e-20 73.5 0.1 3.4e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORY50183.1 - 4.4e-10 39.8 0.0 1.9e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Suv3_N PF18114.1 ORY50183.1 - 0.13 12.4 0.1 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Suv3 helical N-terminal domain RSN1_7TM PF02714.15 ORY50184.1 - 4.3e-61 206.6 17.2 6.4e-61 206.1 17.2 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY50184.1 - 6.2e-28 98.2 0.0 9.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY50184.1 - 9.3e-22 77.5 4.1 1.2e-21 77.1 0.5 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport RNase_HII PF01351.18 ORY50184.1 - 0.097 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribonuclease HII Pyridox_oxase_2 PF12766.7 ORY50185.1 - 0.11 13.1 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Cwf_Cwc_15 PF04889.12 ORY50187.1 - 0.0012 18.6 2.6 0.0012 18.6 2.6 2.3 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Septin PF00735.18 ORY50190.1 - 2e-111 371.8 0.5 2.5e-111 371.5 0.5 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY50190.1 - 1.1e-07 31.9 0.2 3.5e-07 30.3 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY50190.1 - 1.4e-06 28.3 0.1 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 ORY50190.1 - 5.8e-06 25.8 1.1 1.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 ORY50190.1 - 2.8e-05 23.7 0.2 0.0054 16.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY50190.1 - 0.0014 18.7 0.4 1.2 9.2 0.1 2.5 1 1 1 2 2 2 2 Dynamin family ABC_tran PF00005.27 ORY50190.1 - 0.0015 19.1 0.1 0.0026 18.3 0.1 1.8 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.22 ORY50190.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Gtr1_RagA PF04670.12 ORY50190.1 - 0.0048 16.3 0.2 0.018 14.4 0.2 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY50190.1 - 0.0051 16.4 0.2 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 Ras family AAA_16 PF13191.6 ORY50190.1 - 0.0099 16.3 0.2 0.14 12.6 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY50190.1 - 0.02 14.2 0.1 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 ORY50190.1 - 0.024 14.2 0.1 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 ORY50190.1 - 0.027 14.7 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORY50190.1 - 0.028 14.7 0.2 0.3 11.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 ORY50190.1 - 0.03 13.4 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Microtub_bd PF16796.5 ORY50190.1 - 0.075 13.0 0.2 0.46 10.4 0.0 2.3 2 1 0 2 2 2 0 Microtubule binding Fungal_trans PF04082.18 ORY50192.1 - 8.5e-10 38.1 0.0 1.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RSN1_7TM PF02714.15 ORY50193.1 - 5.7e-35 121.0 20.7 8.6e-35 120.4 20.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY50193.1 - 2.7e-14 53.2 3.2 2.7e-14 53.2 3.2 3.6 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY50193.1 - 9.9e-14 51.9 0.0 1.3e-07 32.0 0.0 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Herpes_UL73 PF03554.13 ORY50193.1 - 9.2 6.4 6.5 45 4.1 0.3 2.8 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein EPL1 PF10513.9 ORY50194.1 - 5.1e-27 95.2 0.7 1.1e-26 94.2 0.2 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like FUSC_2 PF13515.6 ORY50196.1 - 7.1e-22 77.9 11.5 7.1e-22 77.9 11.5 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY50196.1 - 2.2e-11 44.1 1.0 4.4e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 ORY50196.1 - 3.5e-09 36.0 3.2 3.5e-07 29.4 0.6 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 ORY50196.1 - 4.6e-09 35.4 17.8 8.8e-08 31.1 7.6 3.0 2 1 1 3 3 3 2 Fusaric acid resistance protein family ArAE_2_N PF10337.9 ORY50196.1 - 0.034 13.2 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal YbjM PF11045.8 ORY50196.1 - 0.33 11.1 9.0 0.83 9.8 0.2 3.4 3 0 0 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae Pro_isomerase PF00160.21 ORY50198.1 - 8.8e-54 182.1 0.0 9.8e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pox_A_type_inc PF04508.12 ORY50199.1 - 0.13 12.1 0.5 0.35 10.8 0.5 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat F-box-like PF12937.7 ORY50200.1 - 0.00015 21.6 0.5 0.00029 20.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY50200.1 - 0.017 15.0 0.2 0.037 13.9 0.2 1.6 1 0 0 1 1 1 0 F-box domain DUF3144 PF11342.8 ORY50200.1 - 0.14 12.5 3.0 0.25 11.6 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) WD40 PF00400.32 ORY50201.1 - 1.5e-15 57.3 13.5 0.0017 19.2 0.3 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50201.1 - 1.9e-06 28.1 2.0 0.061 13.6 0.2 5.8 3 1 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORY50201.1 - 0.0058 16.7 0.0 0.089 12.8 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 ORY50201.1 - 0.063 11.9 1.9 4.8 5.7 0.2 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 HMGL-like PF00682.19 ORY50202.1 - 1.4e-73 247.7 0.0 2.1e-73 247.1 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 ORY50202.1 - 3.4e-28 98.2 0.4 1.1e-27 96.6 0.2 1.9 2 0 0 2 2 2 1 LeuA allosteric (dimerisation) domain SepF PF04472.12 ORY50202.1 - 0.1 12.9 0.0 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 Cell division protein SepF EF-hand_4 PF12763.7 ORY50203.1 - 0.035 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SipA_VBS PF17985.1 ORY50203.1 - 8.7 6.5 6.8 1.3 9.0 0.7 2.5 2 0 0 2 2 2 0 SipA vinculin binding site BRCT_2 PF16589.5 ORY50204.1 - 0.042 14.2 0.0 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Macoilin PF09726.9 ORY50204.1 - 0.29 9.7 10.4 0.32 9.5 10.4 1.0 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 ORY50676.1 - 3.8e-23 82.0 37.3 6.2e-15 55.0 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 ORY50677.1 - 1.4e-11 44.2 0.1 4.5e-11 42.5 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF348 PF03990.14 ORY50677.1 - 0.11 12.2 0.1 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain SCP2 PF02036.17 ORY50678.1 - 2.4e-25 89.0 0.7 2.9e-25 88.7 0.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ORY50678.1 - 1e-06 29.1 0.1 1.3e-06 28.7 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 ORY50678.1 - 0.016 15.6 0.0 0.026 14.9 0.0 1.3 1 1 0 1 1 1 0 Sterol carrier protein domain E1-E2_ATPase PF00122.20 ORY50679.1 - 2e-33 115.4 5.6 6.4e-30 104.0 0.1 3.2 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY50679.1 - 1.7e-25 89.8 5.7 1.7e-25 89.8 5.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY50679.1 - 3.8e-18 65.4 0.0 9.4e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY50679.1 - 4.7e-17 63.0 0.1 4.6e-16 59.7 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY50679.1 - 3.3e-14 52.3 0.0 6.7e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY50679.1 - 0.00029 20.7 0.7 0.0014 18.4 0.5 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY50679.1 - 0.15 12.5 0.1 12 6.3 0.1 3.1 2 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase His_Phos_1 PF00300.22 ORY50680.1 - 5.4e-11 42.5 0.0 7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ADH_N PF08240.12 ORY50681.1 - 3.5e-25 88.0 4.9 6.4e-25 87.2 4.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY50681.1 - 1.3e-18 67.3 0.4 3e-18 66.0 0.3 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY50681.1 - 0.00099 20.2 0.1 0.0029 18.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 ORY50681.1 - 0.026 14.3 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase His_Phos_2 PF00328.22 ORY50682.1 - 0.0061 15.9 0.0 0.66 9.3 0.0 3.0 2 1 0 3 3 3 1 Histidine phosphatase superfamily (branch 2) zinc_ribbon_9 PF14369.6 ORY50682.1 - 0.27 11.5 1.0 0.51 10.7 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbon CFEM PF05730.11 ORY50683.1 - 0.00053 20.0 0.4 0.0011 19.0 0.4 1.6 1 0 0 1 1 1 1 CFEM domain MotA_ExbB PF01618.16 ORY50683.1 - 0.57 9.9 2.7 0.89 9.3 2.7 1.2 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family ANAPC8 PF04049.13 ORY50685.1 - 5.8e-27 94.5 1.0 3.2e-26 92.1 0.2 2.5 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 ORY50685.1 - 2.3e-25 87.3 11.2 5.2e-05 22.9 0.1 6.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORY50685.1 - 1.7e-18 65.2 21.8 0.00028 20.8 1.7 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY50685.1 - 3.3e-15 55.0 17.7 0.00038 20.4 0.0 7.5 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY50685.1 - 7.1e-15 55.4 14.3 4.9e-05 23.9 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY50685.1 - 8.1e-11 42.1 18.3 2e-06 28.0 0.6 5.9 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY50685.1 - 9.8e-11 41.2 15.1 1.7e-07 30.8 0.4 4.8 3 2 2 5 5 5 2 TPR repeat TPR_19 PF14559.6 ORY50685.1 - 1.2e-08 35.3 8.2 0.0038 17.7 0.3 6.2 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY50685.1 - 2.9e-08 33.8 23.4 0.019 15.7 0.3 8.7 5 1 4 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY50685.1 - 3.1e-08 33.1 16.4 0.12 12.4 0.5 6.1 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY50685.1 - 5.4e-07 29.7 10.3 0.003 17.7 1.5 4.0 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORY50685.1 - 0.00025 20.4 12.6 0.0027 17.0 1.5 3.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY50685.1 - 0.0006 20.3 21.6 1.8 9.4 0.0 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY50685.1 - 0.00098 19.3 13.2 0.38 11.2 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY50685.1 - 0.014 15.6 11.1 0.44 10.7 0.1 5.1 4 1 3 7 7 7 0 Tetratricopeptide repeat DUF1729 PF08354.10 ORY50686.1 - 1.9e-152 507.3 0.0 2.6e-152 506.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) SAT PF16073.5 ORY50686.1 - 1.2e-29 103.7 0.0 2.5e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 ORY50686.1 - 8.9e-14 51.5 0.0 1.7e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 ORY50686.1 - 1.4e-11 44.5 0.4 6.9e-11 42.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta Adaptin_N PF01602.20 ORY50688.1 - 8.9e-89 298.4 0.0 1.2e-88 298.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY50688.1 - 7.8e-10 39.0 0.0 4.3e-07 30.1 0.0 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY50688.1 - 2.9e-07 30.8 5.9 0.013 15.9 0.1 4.8 3 2 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 ORY50688.1 - 0.00016 22.1 7.2 6.2 7.4 0.2 5.8 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.22 ORY50688.1 - 0.00034 20.6 8.0 0.46 10.9 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 ORY50688.1 - 0.017 15.1 3.5 4.6 7.4 0.1 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DNA_pol_E_B PF04042.16 ORY50688.1 - 0.036 13.4 0.0 0.079 12.3 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B RTP1_C1 PF10363.9 ORY50688.1 - 0.21 11.7 0.8 26 5.1 0.0 3.5 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Fungal_trans PF04082.18 ORY50689.1 - 2.3e-11 43.2 0.0 4.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY50689.1 - 4.6e-08 33.1 6.9 7.7e-08 32.3 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribophorin_I PF04597.14 ORY50690.1 - 1.5e-24 87.0 0.1 1.7e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I CtaG_Cox11 PF04442.14 ORY50691.1 - 1.1e-60 204.0 0.0 1.6e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Mito_fiss_reg PF05308.11 ORY50691.1 - 0.12 12.4 3.9 0.19 11.8 3.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF5345 PF17280.2 ORY50691.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5345) PRIMA1 PF16101.5 ORY50691.1 - 0.38 10.8 3.4 0.58 10.2 3.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 ORY50691.1 - 0.84 9.1 5.7 1.1 8.6 5.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 ORY50691.1 - 2.8 8.4 12.0 2.7 8.5 9.8 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein MIF4G PF02854.19 ORY50692.1 - 0.0061 16.2 0.8 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain Spidroin_MaSp PF11260.8 ORY50692.1 - 0.077 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 SUIM_assoc PF16619.5 ORY50692.1 - 0.4 10.8 17.9 0.55 10.3 4.9 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4551 PF15087.6 ORY50692.1 - 4.6 6.0 5.7 8 5.2 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pga1 PF10333.9 ORY51205.1 - 9.1e-07 28.9 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator NAD_binding_8 PF13450.6 ORY51206.1 - 4.9e-13 49.1 0.0 3.2e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY51206.1 - 4.3e-06 26.6 0.4 1.7e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY51206.1 - 2.2e-05 23.9 0.0 0.0011 18.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY51206.1 - 0.0001 21.7 1.0 0.00039 19.8 0.1 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ORY51206.1 - 0.00011 22.3 0.1 0.00036 20.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY51206.1 - 0.00081 18.2 0.8 0.0015 17.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ORY51206.1 - 0.00082 18.7 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ORY51206.1 - 0.0013 18.2 0.0 0.003 17.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY51206.1 - 0.0025 17.0 0.1 0.0038 16.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY51206.1 - 0.019 15.5 0.2 0.38 11.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY51206.1 - 0.019 13.4 0.0 0.028 12.8 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORY51206.1 - 0.05 12.7 0.2 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ORY51206.1 - 0.051 12.6 0.1 0.079 12.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 ORY51206.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 ORY51206.1 - 0.14 11.3 0.1 2 7.6 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY51206.1 - 0.26 10.5 0.3 0.53 9.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 ORY51206.1 - 0.26 10.9 1.5 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.18 ORY51208.1 - 6.1e-06 26.3 12.5 1.2e-05 25.3 12.5 1.6 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP59_mtransfer PF11735.8 ORY51209.1 - 3.4e-59 200.4 0.0 4.1e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glycos_transf_2 PF00535.26 ORY51209.1 - 0.17 11.7 0.0 0.5 10.2 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 PDH PF02153.17 ORY51211.1 - 7.5e-15 54.6 0.1 1.1e-14 54.0 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 ORY51211.1 - 1.2e-05 25.8 0.0 3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORY51211.1 - 1.4e-05 25.2 0.0 2.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ORY51211.1 - 8e-05 22.9 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 ORY51211.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 ORY51211.1 - 0.038 13.4 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 ORY51211.1 - 0.13 11.9 0.1 0.38 10.4 0.1 1.9 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Evr1_Alr PF04777.13 ORY51212.1 - 1.4e-26 92.8 0.3 7.4e-26 90.5 0.0 1.9 2 0 0 2 2 2 1 Erv1 / Alr family WD40 PF00400.32 ORY51213.1 - 0.083 13.8 1.4 29 5.8 0.0 4.2 3 1 0 3 3 3 0 WD domain, G-beta repeat TetR_C_35 PF18556.1 ORY51213.1 - 0.15 12.2 0.7 0.43 10.7 0.7 1.7 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain DUF2015 PF09435.10 ORY51214.1 - 2.7e-33 114.2 0.0 3e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Clr5 PF14420.6 ORY51214.1 - 0.052 13.8 0.1 0.094 13.0 0.1 1.4 1 0 0 1 1 1 0 Clr5 domain CENP-T_C PF15511.6 ORY51215.1 - 1.5e-07 31.5 0.0 1.7e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY51215.1 - 4.6e-05 23.5 0.0 5.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY51215.1 - 0.00011 22.5 0.0 0.00013 22.3 0.0 1.2 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY51215.1 - 0.00081 19.8 0.0 0.00082 19.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY51215.1 - 0.00098 19.4 0.0 0.0014 18.9 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY51215.1 - 0.048 13.7 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 ORY51216.1 - 1.7e-51 174.0 3.5 1.9e-51 173.8 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY51216.1 - 5.1e-05 23.6 0.1 7.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY51216.1 - 8e-05 22.7 0.1 0.00016 21.8 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY51216.1 - 0.00027 21.6 1.1 0.00032 21.3 1.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY51216.1 - 0.00062 20.0 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY51216.1 - 0.016 15.3 0.3 0.024 14.7 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY51216.1 - 0.059 13.4 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated RINGv PF12906.7 ORY51217.1 - 3.6e-12 46.2 6.8 6.3e-12 45.4 6.8 1.4 1 0 0 1 1 1 1 RING-variant domain PAC2 PF09754.9 ORY51217.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 PAC2 family EOS1 PF12326.8 ORY51217.1 - 0.078 12.9 0.1 0.27 11.1 0.1 1.9 1 0 0 1 1 1 0 N-glycosylation protein zf-RING_2 PF13639.6 ORY51217.1 - 0.84 10.0 6.3 1.5 9.2 6.3 1.4 1 0 0 1 1 1 0 Ring finger domain His_Phos_2 PF00328.22 ORY51218.1 - 1.2e-40 140.0 0.0 6e-40 137.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-RING_2 PF13639.6 ORY51219.1 - 1.1e-06 28.9 4.8 4.8e-06 26.8 1.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY51219.1 - 0.00058 19.8 0.6 0.0045 17.0 0.6 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY51219.1 - 0.00082 19.2 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY51219.1 - 0.0012 18.6 3.7 0.0019 18.0 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY51219.1 - 0.0015 18.8 6.2 0.0046 17.2 6.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY51219.1 - 0.0024 17.8 0.5 0.015 15.3 0.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY51219.1 - 0.0028 17.5 3.6 0.0058 16.5 0.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY51219.1 - 0.012 15.4 2.9 0.049 13.5 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY51219.1 - 0.021 14.5 1.3 0.042 13.5 1.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORY51219.1 - 0.033 13.9 1.7 2.5 7.9 0.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger DUF2921 PF11145.8 ORY51219.1 - 0.13 10.0 0.4 0.19 9.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) ABC_membrane PF00664.23 ORY51221.1 - 9e-49 166.6 20.6 5.9e-26 91.7 9.2 3.4 4 0 0 4 4 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORY51221.1 - 1.5e-45 155.1 0.0 4.5e-28 98.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY51221.1 - 1.9e-08 34.0 0.0 0.3 10.5 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 ORY51221.1 - 6.6e-08 31.9 0.0 0.002 17.3 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 ORY51221.1 - 3.6e-07 29.8 0.1 0.035 13.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY51221.1 - 6.9e-07 29.8 7.8 0.0028 18.0 0.4 3.3 4 0 0 4 4 2 2 AAA ATPase domain AAA_25 PF13481.6 ORY51221.1 - 1e-06 28.4 0.1 0.042 13.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORY51221.1 - 2.4e-05 24.9 0.1 0.0048 17.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORY51221.1 - 6.9e-05 22.8 0.6 1.1 9.0 0.0 3.7 4 0 0 4 4 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY51221.1 - 0.00015 22.1 0.3 0.34 11.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY51221.1 - 0.00095 18.6 0.0 0.096 12.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.17 ORY51221.1 - 0.0017 18.5 1.3 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain NACHT PF05729.12 ORY51221.1 - 0.0017 18.3 0.1 1.8 8.5 0.0 3.1 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 ORY51221.1 - 0.0017 17.6 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 ORY51221.1 - 0.0025 17.8 0.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase DEAD PF00270.29 ORY51221.1 - 0.005 16.6 0.1 6.8 6.4 0.0 2.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 ORY51221.1 - 0.0065 16.5 0.4 0.71 10.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY51221.1 - 0.0084 16.3 0.1 7.7 6.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY51221.1 - 0.011 15.1 0.1 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 ORY51221.1 - 0.012 15.2 0.0 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 ORY51221.1 - 0.021 14.5 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 ORY51221.1 - 0.023 14.0 0.2 1.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 ORY51221.1 - 0.024 15.1 0.0 0.78 10.2 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 ORY51221.1 - 0.025 14.3 0.0 3.2 7.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein TrwB_AAD_bind PF10412.9 ORY51221.1 - 0.029 13.3 0.1 6.4 5.6 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 ORY51221.1 - 0.039 13.5 1.9 0.65 9.6 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ORY51221.1 - 0.044 14.3 0.0 14 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY51221.1 - 0.047 13.7 0.4 8 6.5 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 ORY51221.1 - 0.049 13.3 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Perilipin PF03036.16 ORY51221.1 - 0.059 12.4 0.4 0.1 11.6 0.4 1.2 1 0 0 1 1 1 0 Perilipin family NB-ARC PF00931.22 ORY51221.1 - 0.15 11.2 0.0 5.7 6.0 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_11 PF13086.6 ORY51221.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORY51221.1 - 0.16 12.0 0.0 7.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORY51221.1 - 0.25 11.0 0.0 7.2 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 ORY51221.1 - 0.29 11.2 0.7 14 5.7 0.0 2.9 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.23 ORY51221.1 - 0.68 10.0 1.9 33 4.5 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DUF2975 PF11188.8 ORY51221.1 - 4.5 7.2 9.8 5 7.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF3292 PF11696.8 ORY51222.1 - 3.3e-10 39.0 9.4 6.1e-05 21.6 0.2 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF3292) GPI-anchored PF10342.9 ORY51224.1 - 0.03 15.1 5.4 0.031 15.1 0.4 2.8 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pescadillo_N PF06732.11 ORY51225.1 - 5.9e-122 406.5 0.0 1.4e-121 405.3 0.0 1.6 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 ORY51225.1 - 1.3e-09 38.4 0.0 2.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY51225.1 - 0.0041 17.5 0.0 0.035 14.5 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Sporozoite_P67 PF05642.11 ORY51225.1 - 0.25 9.4 5.8 0.37 8.8 5.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GCIP PF13324.6 ORY51225.1 - 0.27 10.8 7.1 0.53 9.8 7.1 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting PI3K_1B_p101 PF10486.9 ORY51225.1 - 2.3 5.9 13.6 3.2 5.4 13.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YL1 PF05764.13 ORY51225.1 - 3 7.9 32.6 0.059 13.5 25.2 1.9 2 0 0 2 2 2 0 YL1 nuclear protein CENP-B_dimeris PF09026.10 ORY51225.1 - 7.9 6.9 18.0 25 5.3 18.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spt5-NGN PF03439.13 ORY51226.1 - 8.4e-22 76.9 0.0 1.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 ORY51226.1 - 1.9e-18 67.2 8.1 1.9e-18 67.2 8.1 1.8 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 ORY51226.1 - 2.2e-15 56.0 15.4 7.6e-06 25.7 0.3 6.7 6 0 0 6 6 6 4 KOW motif HAS-barrel PF09378.10 ORY51226.1 - 1.7 8.8 4.1 11 6.3 1.1 3.4 2 1 0 2 2 2 0 HAS barrel domain ABC_membrane PF00664.23 ORY51757.1 - 5.6e-23 82.0 1.4 6.8e-23 81.7 1.4 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY51758.1 - 1.4e-28 100.1 0.0 6.7e-28 97.9 0.0 2.0 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY51758.1 - 1.7e-06 27.6 0.3 0.00015 21.3 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 ORY51758.1 - 0.0095 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 ORY51758.1 - 0.02 14.6 0.1 0.053 13.3 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY51758.1 - 0.049 13.9 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 ORY51758.1 - 0.076 12.8 0.1 15 5.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 ORY51758.1 - 0.13 12.4 0.3 0.35 11.0 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NRN1 PF15056.6 ORY51759.1 - 0.13 12.4 2.1 0.15 12.2 0.5 1.9 2 0 0 2 2 2 0 Neuritin protein family zf-RING_4 PF14570.6 ORY51759.1 - 0.34 10.8 2.8 15 5.5 0.1 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ubiquitin PF00240.23 ORY51760.1 - 7.5e-35 118.5 0.5 9.6e-35 118.2 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY51760.1 - 1.8e-16 59.7 0.6 2.3e-16 59.4 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY51760.1 - 1.1e-05 25.8 0.1 4.1e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ribosomal_L40e PF01020.17 ORY51760.1 - 0.00054 19.8 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L40e family TBK1_ULD PF18396.1 ORY51760.1 - 0.0027 17.6 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY51760.1 - 0.0032 17.8 0.0 0.0044 17.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY51760.1 - 0.0045 17.0 0.6 2.3 8.3 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY51760.1 - 0.0047 17.0 0.1 0.011 15.8 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY51760.1 - 0.024 15.2 0.1 0.027 15.0 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY51760.1 - 0.083 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain NIF3 PF01784.18 ORY51761.1 - 8.8e-58 195.8 0.0 1e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Con-6 PF10346.9 ORY51764.1 - 6.2e-18 64.5 5.5 7.2e-09 35.5 0.2 2.5 3 0 0 3 3 3 2 Conidiation protein 6 Tricorn_C1 PF14684.6 ORY51764.1 - 0.03 14.4 0.2 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease C1 domain Sod_Fe_N PF00081.22 ORY51764.1 - 0.073 13.6 4.6 0.084 13.4 3.6 1.6 1 1 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain CinA_KH PF18146.1 ORY51764.1 - 0.36 11.0 3.5 1.4 9.1 1.8 2.1 1 1 1 2 2 2 0 Damage-inducible protein CinA KH domain FAD_binding_7 PF03441.14 ORY51765.1 - 2.3e-78 262.3 1.4 3.5e-78 261.7 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY51765.1 - 2.2e-34 118.8 0.0 3.7e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Peptidase_M3 PF01432.20 ORY51766.1 - 5.9e-130 434.6 0.0 7.1e-130 434.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 ORY51766.1 - 0.032 14.5 0.0 0.058 13.7 0.0 1.3 1 0 0 1 1 1 0 Effector protein F-box-like PF12937.7 ORY51767.1 - 0.00023 21.0 1.5 0.00052 19.9 1.5 1.7 1 0 0 1 1 1 1 F-box-like SSF PF00474.17 ORY51768.1 - 9.2e-17 61.0 30.9 1.5e-16 60.3 30.9 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family SnoaL_2 PF12680.7 ORY51769.1 - 2.3e-07 31.4 0.0 5e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY51769.1 - 2.1e-05 24.3 0.0 3.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Con-6 PF10346.9 ORY51770.1 - 6.7e-17 61.2 1.0 1.4e-07 31.4 0.2 2.7 2 0 0 2 2 2 2 Conidiation protein 6 Sod_Fe_N PF00081.22 ORY51770.1 - 0.38 11.3 2.3 0.98 9.9 2.3 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Zn_clus PF00172.18 ORY51771.1 - 2.3e-05 24.4 2.9 3.7e-05 23.7 2.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF678 PF05077.12 ORY51771.1 - 0.26 11.4 3.6 0.58 10.3 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF678) Zn_clus PF00172.18 ORY51772.1 - 0.0065 16.6 5.0 0.011 15.8 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SprB PF13573.6 ORY51773.1 - 0.0059 16.4 0.1 0.018 14.8 0.1 1.9 1 0 0 1 1 1 1 SprB repeat DUF2062 PF09835.9 ORY51773.1 - 0.011 15.5 0.2 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF202 PF02656.15 ORY51773.1 - 0.013 15.9 0.1 0.029 14.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF202) CD34_antigen PF06365.12 ORY51773.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family CcmD PF04995.14 ORY51773.1 - 2.7 8.2 5.6 4.6 7.4 5.6 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Sec2p PF06428.11 ORY51775.1 - 1.2e-09 38.0 7.0 1.2e-09 38.0 7.0 2.3 2 1 1 3 3 2 1 GDP/GTP exchange factor Sec2p TMF_DNA_bd PF12329.8 ORY51775.1 - 0.0087 16.0 9.9 0.64 10.1 8.3 2.9 1 1 1 2 2 2 1 TATA element modulatory factor 1 DNA binding DUF4472 PF14739.6 ORY51775.1 - 0.011 16.4 3.6 0.038 14.7 3.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) SHE3 PF17078.5 ORY51775.1 - 0.026 14.2 2.8 0.047 13.4 2.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Nup88 PF10168.9 ORY51775.1 - 0.075 10.8 2.4 0.11 10.2 2.4 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF1640 PF07798.11 ORY51775.1 - 0.14 12.2 5.7 0.27 11.3 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TSC22 PF01166.18 ORY51775.1 - 0.34 11.3 2.5 6.9 7.1 0.1 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family PI3K_P85_iSH2 PF16454.5 ORY51775.1 - 0.4 10.3 7.1 1.5 8.4 0.2 2.5 2 1 1 3 3 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SOGA PF11365.8 ORY51775.1 - 0.41 11.8 6.4 1.1 10.5 4.5 2.6 1 1 0 2 2 2 0 Protein SOGA Cnn_1N PF07989.11 ORY51775.1 - 0.51 10.5 5.7 4.7 7.4 1.3 2.8 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Cob_adeno_trans PF01923.18 ORY51775.1 - 0.55 10.3 4.3 1 9.4 1.2 2.5 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Uds1 PF15456.6 ORY51775.1 - 0.61 10.3 10.7 0.046 13.9 4.3 2.4 2 0 0 2 2 2 0 Up-regulated During Septation bZIP_1 PF00170.21 ORY51775.1 - 0.81 9.8 5.5 0.6 10.2 0.2 3.0 1 1 2 3 3 3 0 bZIP transcription factor DivIVA PF05103.13 ORY51775.1 - 1 9.4 8.4 0.38 10.9 4.2 2.0 2 0 0 2 2 2 0 DivIVA protein CENP-F_leu_zip PF10473.9 ORY51775.1 - 3.9 7.5 16.9 0.8 9.7 10.6 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCC-bdg_PDZ PF10506.9 ORY51775.1 - 4 7.5 6.5 7.2 6.7 0.4 3.1 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1664 PF07889.12 ORY51775.1 - 4.3 7.4 5.2 2.6 8.1 1.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) MbeD_MobD PF04899.12 ORY51775.1 - 4.6 7.4 9.2 9.5 6.4 0.3 3.5 2 1 0 3 3 3 0 MbeD/MobD like YabA PF06156.13 ORY51775.1 - 8 7.2 9.1 6.5 7.4 1.3 2.9 2 1 1 3 3 3 0 Initiation control protein YabA Aldedh PF00171.22 ORY51776.1 - 1.7e-121 406.0 0.0 2e-121 405.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SesA PF17107.5 ORY51777.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3989 PF13150.6 ORY51777.1 - 1.6 8.5 6.2 2 8.2 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3989) PGP_phosphatase PF09419.10 ORY52172.1 - 5.1e-19 68.5 0.0 4.5e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 ORY52172.1 - 0.0075 16.3 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Band_7 PF01145.25 ORY52173.1 - 4.9e-08 33.2 0.0 4.9e-08 33.2 0.0 3.6 3 1 0 3 3 3 1 SPFH domain / Band 7 family Flot PF15975.5 ORY52173.1 - 0.0022 18.2 13.9 0.0022 18.2 13.9 2.8 1 1 2 3 3 3 1 Flotillin Sugar_tr PF00083.24 ORY52174.1 - 3.2e-73 247.1 24.2 3.7e-73 246.9 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY52174.1 - 3.6e-24 85.4 20.4 3.6e-24 85.4 20.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5588 PF17826.1 ORY52175.1 - 0.23 10.3 0.8 0.34 9.8 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5588) Sugar_tr PF00083.24 ORY52176.1 - 5.5e-09 35.4 3.8 5.5e-09 35.4 3.8 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter FGGY_N PF00370.21 ORY52177.1 - 2.1e-13 50.4 0.0 2.9e-10 40.1 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ORY52177.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain LRRNT_2 PF08263.12 ORY52177.1 - 2.4 8.5 4.4 4 7.8 0.2 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain F-box-like PF12937.7 ORY52178.1 - 0.001 18.9 0.2 0.0038 17.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like DnaJ PF00226.31 ORY52179.1 - 1.7e-20 72.9 0.2 2.8e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 ORY52179.1 - 3.7e-16 59.5 0.0 5.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 ORY52179.1 - 1.8e-13 50.6 14.1 3.2e-13 49.8 14.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY52179.1 - 0.026 14.5 1.5 0.026 14.5 1.5 3.1 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein zinc-ribbons_6 PF07191.12 ORY52179.1 - 5.4 7.1 9.2 2.1 8.4 2.3 2.4 2 0 0 2 2 2 0 zinc-ribbons F-box-like PF12937.7 ORY52180.1 - 0.00098 19.0 0.7 0.0039 17.0 0.2 2.3 2 0 0 2 2 2 1 F-box-like SCF PF02404.15 ORY52180.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Stem cell factor DUF1979 PF09322.10 ORY52180.1 - 0.16 11.9 0.3 9.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) Alba PF01918.21 ORY52181.1 - 0.0064 16.3 0.0 0.28 11.0 0.0 2.5 3 0 0 3 3 3 2 Alba BRCT PF00533.26 ORY52182.1 - 3.6e-32 110.6 0.2 3.4e-08 33.7 0.0 5.8 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY52182.1 - 9.8e-29 99.1 6.7 1.9e-08 34.1 0.0 5.4 5 0 0 5 5 5 4 twin BRCT domain BRCT_2 PF16589.5 ORY52182.1 - 1.1e-09 38.6 0.0 0.089 13.2 0.0 5.5 6 0 0 6 6 6 3 BRCT domain, a BRCA1 C-terminus domain Med22 PF06179.12 ORY52184.1 - 2e-16 60.1 0.1 3.4e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF3479 PF11965.8 ORY52184.1 - 0.016 15.4 0.5 0.028 14.5 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3479) DHQ_synthase PF01761.20 ORY52184.1 - 0.016 14.4 0.3 0.042 13.0 0.3 1.7 1 1 0 1 1 1 0 3-dehydroquinate synthase F-box-like PF12937.7 ORY52185.1 - 0.00012 21.9 1.3 0.0025 17.7 0.1 2.7 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.7 ORY52186.1 - 0.0022 17.8 0.4 0.0022 17.8 0.4 2.4 2 0 0 2 2 2 1 F-box-like Nup96 PF12110.8 ORY52187.1 - 7.3e-100 333.8 0.0 1.3e-99 333.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 RRM_1 PF00076.22 ORY52188.1 - 2.6e-33 113.7 3.8 7.6e-16 57.7 0.0 5.2 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY52188.1 - 7e-07 29.3 0.0 0.0067 16.5 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 ORY52188.1 - 0.0013 18.5 0.0 0.3 11.0 0.0 3.5 3 1 1 4 4 4 1 Occluded RNA-recognition motif TcpA PF05946.12 ORY52188.1 - 0.04 14.0 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA RRM_9 PF18444.1 ORY52188.1 - 0.12 12.2 0.2 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif F-box-like PF12937.7 ORY52190.1 - 0.0015 18.4 0.3 0.0044 16.9 0.3 1.9 1 0 0 1 1 1 1 F-box-like DUF72 PF01904.18 ORY52190.1 - 0.17 12.0 0.1 0.49 10.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF72 Ras PF00071.22 ORY52191.1 - 1.9e-45 154.4 0.0 2.2e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY52191.1 - 6.1e-18 65.2 0.0 8.1e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY52191.1 - 8.6e-07 28.6 0.0 9.4e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY52191.1 - 6.1e-06 25.9 0.0 1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MutS_I PF01624.20 ORY52192.1 - 0.00036 20.7 1.4 0.00043 20.5 0.1 1.7 2 0 0 2 2 2 1 MutS domain I zf-C2H2_2 PF12756.7 ORY52192.1 - 0.11 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF1178 PF06676.11 ORY52192.1 - 0.42 11.0 13.7 0.64 10.4 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1178) Connexin PF00029.19 ORY52192.1 - 2.9 7.6 5.3 50 3.6 4.0 2.1 2 0 0 2 2 2 0 Connexin CBM_1 PF00734.18 ORY52193.1 - 2e-35 120.4 91.6 3.5e-11 42.9 13.4 5.7 5 0 0 5 5 5 4 Fungal cellulose binding domain DUF4614 PF15391.6 ORY52193.1 - 0.0059 16.6 10.2 0.0059 16.6 10.2 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4614) Apt1 PF10351.9 ORY52193.1 - 0.17 10.7 23.6 0.17 10.7 11.3 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF913 PF06025.12 ORY52193.1 - 2.8 6.8 8.1 0.79 8.6 0.8 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF908 PF06012.12 ORY52193.1 - 4.1 6.7 28.5 0.23 10.8 8.5 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF908) Med19 PF10278.9 ORY52194.1 - 3e-06 27.3 0.7 0.00039 20.4 1.6 2.2 2 0 0 2 2 2 2 Mediator of RNA pol II transcription subunit 19 Las1 PF04031.13 ORY52195.1 - 3.4e-50 170.1 0.2 6.5e-50 169.2 0.2 1.5 1 0 0 1 1 1 1 Las1-like PspA_IM30 PF04012.12 ORY52195.1 - 0.027 14.1 0.2 0.048 13.2 0.2 1.4 1 0 0 1 1 1 0 PspA/IM30 family PET117 PF15786.5 ORY52195.1 - 0.08 13.2 0.0 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial FHA PF00498.26 ORY52707.1 - 4e-13 49.5 0.0 9e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF1664 PF07889.12 ORY52707.1 - 0.00027 21.0 4.2 0.049 13.7 0.7 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 ORY52707.1 - 0.002 18.5 7.6 0.002 18.5 7.6 3.4 2 2 1 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Yop-YscD_cpl PF16697.5 ORY52707.1 - 0.0023 18.2 0.0 0.006 16.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Lipoprotein_7 PF01540.16 ORY52707.1 - 0.0028 17.0 2.0 0.0049 16.2 2.0 1.3 1 0 0 1 1 1 1 Adhesin lipoprotein AAA_13 PF13166.6 ORY52707.1 - 0.0036 16.0 4.0 0.0036 16.0 4.0 1.9 1 1 1 2 2 2 1 AAA domain DUF812 PF05667.11 ORY52707.1 - 0.008 15.1 8.2 0.19 10.6 7.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF812) DHR10 PF18595.1 ORY52707.1 - 0.035 14.1 0.8 0.035 14.1 0.8 3.5 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain AIP3 PF03915.13 ORY52707.1 - 0.07 12.2 3.5 0.18 10.9 0.1 2.2 2 0 0 2 2 2 0 Actin interacting protein 3 KxDL PF10241.9 ORY52707.1 - 0.078 13.3 6.1 0.038 14.3 1.3 2.7 3 1 0 3 3 2 0 Uncharacterized conserved protein Spectrin PF00435.21 ORY52707.1 - 0.17 12.4 11.2 3.1 8.3 0.3 2.8 3 0 0 3 3 2 0 Spectrin repeat APG6_N PF17675.1 ORY52707.1 - 0.18 12.4 12.1 11 6.5 8.6 2.8 3 0 0 3 3 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 ORY52707.1 - 0.34 10.2 12.9 0.55 9.5 8.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 ORY52707.1 - 0.66 10.2 10.9 1.2 9.4 0.4 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.9 ORY52707.1 - 0.68 10.3 5.0 2.9 8.3 1.2 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4937 PF16291.5 ORY52707.1 - 0.7 10.2 2.8 1.5 9.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4937 CENP-F_leu_zip PF10473.9 ORY52707.1 - 0.93 9.5 12.0 2.6 8.1 6.0 2.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 ORY52707.1 - 1.1 8.5 5.2 1.4 8.2 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) TRAF_BIRC3_bd PF16673.5 ORY52707.1 - 1.2 9.0 4.3 9.5 6.1 0.2 3.2 2 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain CCDC144C PF14915.6 ORY52707.1 - 2.1 7.4 10.0 0.79 8.8 5.9 2.0 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Cnn_1N PF07989.11 ORY52707.1 - 2.2 8.5 5.5 11 6.3 0.8 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CC2-LZ PF16516.5 ORY52707.1 - 2.3 8.6 10.4 0.72 10.3 0.1 2.8 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Muted PF14942.6 ORY52707.1 - 2.7 8.3 5.4 3.5 8.0 1.5 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Nup54 PF13874.6 ORY52707.1 - 4.5 7.4 9.2 0.91 9.6 3.9 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 ORY52707.1 - 6.9 5.4 10.8 16 4.2 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein TauD PF02668.16 ORY52708.1 - 1.1e-60 205.8 0.2 1.5e-60 205.3 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ORY52709.1 - 3e-36 125.1 26.1 3e-36 125.1 26.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 ORY52710.1 - 7.2e-06 25.2 0.1 1.6e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY52710.1 - 0.00016 21.7 8.8 0.00029 20.9 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IATP PF04568.12 ORY52711.1 - 2.4e-06 27.9 0.9 2.4e-06 27.9 0.9 1.6 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP FYVE_2 PF02318.16 ORY52711.1 - 0.11 12.7 0.1 0.13 12.5 0.1 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger CsbD PF05532.12 ORY52712.1 - 1.9e-11 43.6 14.5 0.003 17.4 0.3 3.5 2 1 1 3 3 3 3 CsbD-like Casc1_N PF15927.5 ORY52712.1 - 0.037 13.7 1.0 0.058 13.1 1.0 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus MFS_1 PF07690.16 ORY52715.1 - 7e-36 123.9 46.0 7e-36 123.9 46.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY52715.1 - 0.00013 20.6 8.0 0.00023 19.8 8.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) COX5A PF02284.16 ORY52717.1 - 1.1e-37 128.1 0.2 1.4e-37 127.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF1857 PF08982.11 ORY52717.1 - 0.035 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1857) Bromo_TP PF07524.13 ORY52718.1 - 1.5e-10 40.9 0.0 2.4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 ORY52718.1 - 3.3e-06 27.6 5.5 6e-06 26.7 3.1 2.6 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term TP_methylase PF00590.20 ORY52720.1 - 2e-34 119.4 0.0 4.3e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 ORY52720.1 - 0.00055 19.3 0.1 0.001 18.5 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 ORY52720.1 - 0.0042 17.5 0.1 0.016 15.7 0.1 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORY52720.1 - 0.006 16.2 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal MFS_1 PF07690.16 ORY52721.1 - 1.3e-37 129.5 42.2 1.3e-37 129.5 42.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY52721.1 - 6.2e-10 38.1 10.0 8.9e-10 37.6 10.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3818 PF12825.7 ORY52723.1 - 3.4e-78 263.1 0.0 4.5e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORY52723.1 - 1.7e-30 105.7 0.0 7.7e-30 103.6 0.0 2.1 2 0 0 2 2 2 1 PX-associated Ribosomal_L21e PF01157.18 ORY52724.1 - 3.4e-45 152.0 4.7 5.7e-45 151.3 4.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e Surface_Ag_2 PF01617.17 ORY52724.1 - 0.055 12.9 0.1 0.065 12.7 0.1 1.2 1 0 0 1 1 1 0 Surface antigen MFS_1 PF07690.16 ORY52725.1 - 5.7e-32 111.0 26.0 5.7e-32 111.0 26.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY52725.1 - 4.6e-14 52.1 5.0 4.6e-14 52.1 5.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Pex14_N PF04695.13 ORY52726.1 - 4e-21 76.3 0.1 2.1e-15 57.7 0.0 4.1 2 2 1 3 3 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region NPV_P10 PF05531.12 ORY52726.1 - 0.0018 18.7 1.9 0.018 15.5 0.1 2.4 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein HD_4 PF13328.6 ORY52726.1 - 0.0042 16.8 1.4 0.0079 15.9 1.4 1.5 1 0 0 1 1 1 1 HD domain Myosin_tail_1 PF01576.19 ORY52726.1 - 0.0082 14.0 7.8 0.011 13.6 7.8 1.1 1 0 0 1 1 1 1 Myosin tail DUF4407 PF14362.6 ORY52726.1 - 0.0094 15.3 0.4 0.013 14.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF5610 PF18433.1 ORY52726.1 - 0.024 15.1 2.1 0.03 14.8 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) SHE3 PF17078.5 ORY52726.1 - 0.034 13.9 2.0 0.05 13.3 2.0 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF1319 PF07028.11 ORY52726.1 - 0.05 13.8 4.2 0.39 11.0 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF1043 PF06295.12 ORY52726.1 - 0.053 13.5 2.4 0.12 12.4 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) BicD PF09730.9 ORY52726.1 - 0.055 11.9 5.4 0.076 11.4 5.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF2664 PF10867.8 ORY52726.1 - 0.063 13.7 0.1 0.15 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) Baculo_PEP_C PF04513.12 ORY52726.1 - 0.077 13.0 0.5 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 ORY52726.1 - 0.19 9.2 4.9 0.26 8.8 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Med9 PF07544.13 ORY52726.1 - 0.63 10.2 5.8 5.7 7.1 0.5 2.7 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_M41 PF01434.18 ORY52726.1 - 0.83 9.5 5.5 1.5 8.6 0.4 2.1 1 1 1 2 2 2 0 Peptidase family M41 V-SNARE PF05008.15 ORY52726.1 - 1.5 9.2 6.7 2.1 8.8 1.9 2.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF5320 PF17253.2 ORY52726.1 - 2.4 9.3 6.0 57 4.9 1.0 3.9 3 1 0 3 3 3 0 Family of unknown function (DUF5320) Prefoldin_2 PF01920.20 ORY52726.1 - 7.5 6.6 10.3 2.9 7.9 3.9 2.4 2 0 0 2 2 2 0 Prefoldin subunit Ureidogly_lyase PF04115.12 ORY52727.1 - 5.2e-30 104.6 0.0 6.6e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase Piwi PF02171.17 ORY52728.1 - 1.7e-56 191.7 0.0 4.4e-56 190.3 0.0 1.6 1 1 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 ORY52728.1 - 1.5e-13 50.2 0.0 4.1e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 ORY52728.1 - 9.8e-13 48.9 0.0 1.9e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 ORY52728.1 - 1.5e-11 44.3 0.0 3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Serpulina_VSP PF05540.11 ORY52728.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Serpulina hyodysenteriae variable surface protein adh_short PF00106.25 ORY52813.1 - 2.5e-44 151.1 0.0 3.8e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY52813.1 - 2.4e-28 99.3 0.0 3.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY52813.1 - 7.2e-13 48.8 3.2 1e-11 45.0 3.2 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY52813.1 - 1.9e-08 34.0 0.0 3.3e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY52813.1 - 0.0033 16.6 0.1 0.0044 16.2 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY52813.1 - 0.0057 16.6 0.2 0.0092 15.9 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY52813.1 - 0.039 13.4 0.3 0.083 12.3 0.3 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase CCDC142 PF14923.6 ORY52813.1 - 0.2 10.3 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil protein 142 TPMT PF05724.11 ORY52814.1 - 3.5e-31 108.6 0.2 6.8e-31 107.6 0.2 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 ORY52814.1 - 2.1e-10 41.1 0.0 4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY52814.1 - 3.8e-09 36.5 0.0 5.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY52814.1 - 2.6e-08 34.4 0.0 4.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY52814.1 - 5.7e-07 29.5 0.0 7.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY52814.1 - 1.4e-05 25.8 0.0 2.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORY52814.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB APH PF01636.23 ORY52816.1 - 1.6e-40 139.6 0.0 2.6e-40 138.9 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY52816.1 - 0.00044 19.7 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase RIO1 PF01163.22 ORY52816.1 - 0.0033 17.0 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 ORY52816.1 - 0.24 10.2 0.0 1.5 7.6 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Med31 PF05669.12 ORY52817.1 - 5e-23 80.9 0.8 6.4e-23 80.6 0.8 1.1 1 0 0 1 1 1 1 SOH1 F-box-like PF12937.7 ORY52818.1 - 0.0057 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like Sdh_cyt PF01127.22 ORY52819.1 - 3e-17 62.8 2.8 3.9e-17 62.4 2.8 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ABC2_membrane_2 PF12679.7 ORY52819.1 - 0.21 10.9 5.0 0.33 10.2 5.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Ferrochelatase PF00762.19 ORY52821.1 - 4.1e-101 338.2 0.0 4.7e-101 338.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Ras PF00071.22 ORY52822.1 - 4e-47 159.8 0.2 4.6e-47 159.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY52822.1 - 9.8e-16 58.1 0.0 1.4e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY52822.1 - 5e-09 36.0 0.1 2.3e-08 33.8 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 ORY52822.1 - 1.8e-06 27.5 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY52822.1 - 0.00016 21.7 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY52822.1 - 0.00049 20.0 0.2 0.071 13.0 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORY52822.1 - 0.00095 18.6 0.0 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ORY52822.1 - 0.002 17.7 0.0 0.017 14.7 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ORY52822.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 ORY52822.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 ORY52823.1 - 2e-16 60.3 0.1 6.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY52823.1 - 4.6e-10 39.5 0.0 0.00018 21.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY52823.1 - 1.2e-08 35.2 0.0 0.0051 17.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY52823.1 - 0.0044 17.0 0.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein NHR2 PF08788.11 ORY52823.1 - 0.0082 15.9 0.4 0.5 10.2 0.1 2.4 2 0 0 2 2 2 1 NHR2 domain like Acetyltransf_CG PF14542.6 ORY52823.1 - 0.018 15.2 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 ORY52823.1 - 0.019 15.1 0.0 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain His_Phos_2 PF00328.22 ORY52824.1 - 1.4e-14 54.3 0.0 2.1e-07 30.7 0.2 3.2 2 2 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) Alpha_GJ PF03229.13 ORY52825.1 - 0.061 13.9 17.7 0.062 13.9 0.4 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J Hira PF07569.11 ORY52826.1 - 4.5e-55 186.8 2.6 5.2e-53 180.0 2.6 2.7 1 1 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.32 ORY52826.1 - 5e-28 96.8 18.3 1.4e-07 32.1 0.3 6.5 7 0 0 7 7 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY52826.1 - 2.5e-10 40.5 0.8 0.39 11.0 0.0 5.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY52826.1 - 0.00084 18.4 0.1 5.9 5.7 0.0 4.2 3 1 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CDC45 PF02724.14 ORY52826.1 - 0.056 11.7 12.8 0.083 11.2 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nbas_N PF15492.6 ORY52826.1 - 0.18 11.1 0.8 1.5 8.0 0.0 2.8 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nop14 PF04147.12 ORY52826.1 - 0.25 9.5 13.6 0.36 9.0 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 ORY52826.1 - 1.2 9.2 12.0 2.5 8.2 12.0 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Pep1_7 PF17232.2 ORY52826.1 - 1.4 9.5 7.8 2.1 8.9 6.5 2.0 1 1 0 1 1 1 0 Elicitor peptide 1-7 TP53IP5 PF15331.6 ORY52826.1 - 4.8 7.3 7.4 8.8 6.4 7.4 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 CCDC106 PF15794.5 ORY52826.1 - 5.8 6.6 9.7 10 5.7 9.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNA_pol_Rpc4 PF05132.14 ORY52826.1 - 8.8 6.7 10.8 0.25 11.8 2.5 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Utp21 PF04192.12 ORY52827.1 - 1.9e-68 230.5 0.1 1.9e-68 230.5 0.1 1.5 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 ORY52827.1 - 5.3e-14 52.4 2.4 0.0014 19.4 0.0 7.7 9 0 0 9 9 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY52827.1 - 1.4e-13 50.9 0.0 0.42 10.9 0.0 6.8 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY52827.1 - 0.0017 17.2 0.0 1.5 7.4 0.0 3.4 4 0 0 4 4 4 2 Nup133 N terminal like Utp12 PF04003.12 ORY52827.1 - 0.0064 16.8 0.7 0.014 15.7 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family RNF111_N PF15303.6 ORY52827.1 - 0.057 13.2 7.3 0.12 12.1 7.3 1.5 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Cwf_Cwc_15 PF04889.12 ORY52827.1 - 1 9.1 11.0 2 8.1 11.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 ORY52827.1 - 2.2 7.5 9.4 4.7 6.5 9.4 1.4 1 0 0 1 1 1 0 BUD22 PQQ_3 PF13570.6 ORY52827.1 - 3.3 8.3 4.6 3.6 8.2 0.1 3.3 4 0 0 4 4 2 0 PQQ-like domain SR-25 PF10500.9 ORY52827.1 - 5.1 6.6 16.4 14 5.2 16.4 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Atrophin-1 PF03154.15 ORY52827.1 - 5.2 5.2 7.5 8.2 4.6 7.5 1.2 1 0 0 1 1 1 0 Atrophin-1 family ANAPC4_WD40 PF12894.7 ORY52828.1 - 0.00044 20.5 0.0 0.097 13.0 0.0 2.9 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY52828.1 - 0.0012 19.6 0.2 2.3 9.2 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-C3HC4 PF00097.25 ORY52829.1 - 6.9e-08 32.2 5.8 1.6e-07 31.1 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY52829.1 - 4.7e-06 26.5 3.5 4.7e-06 26.5 3.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY52829.1 - 5.5e-06 26.6 7.1 5.5e-06 26.6 7.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY52829.1 - 6.7e-06 25.9 8.7 1.8e-05 24.5 8.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY52829.1 - 2.2e-05 24.3 5.3 4.4e-05 23.4 5.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY52829.1 - 0.00044 20.0 1.7 0.00044 20.0 1.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 ORY52829.1 - 0.0018 18.1 2.3 0.0018 18.1 2.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_4 PF15227.6 ORY52829.1 - 0.014 15.5 3.8 0.014 15.5 3.8 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY52829.1 - 0.039 14.2 10.6 0.15 12.4 10.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY52829.1 - 0.4 10.8 7.2 1.4 9.0 7.2 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf_CCCH_4 PF18345.1 ORY52829.1 - 0.84 9.8 6.9 2.4 8.3 6.9 1.9 1 0 0 1 1 1 0 Zinc finger domain CAP_N PF01213.19 ORY52829.1 - 1.4 8.3 3.5 1.8 7.9 3.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Prok-RING_4 PF14447.6 ORY52829.1 - 8 6.4 14.5 1.1 9.2 8.7 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 PI3_PI4_kinase PF00454.27 ORY52830.1 - 1.2e-36 126.8 0.0 1.8e-36 126.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ANAPC5 PF12862.7 ORY52831.1 - 0.16 12.0 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 RTA1 PF04479.13 ORY52832.1 - 1.7e-57 194.4 9.9 1.7e-57 194.4 9.9 1.5 2 0 0 2 2 2 1 RTA1 like protein Form-deh_trans PF09163.11 ORY52832.1 - 0.54 10.1 2.6 10 6.0 0.3 2.6 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane BIR PF00653.21 ORY52833.1 - 8.3e-31 106.5 0.6 3.3e-14 53.3 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain NFACT-R_2 PF18297.1 ORY52834.1 - 0.16 12.2 1.6 0.27 11.5 0.5 1.8 1 1 1 2 2 2 0 NFACT protein RNA binding domain Novirhabdo_Nv PF05554.11 ORY52835.1 - 0.14 11.9 0.4 0.88 9.3 0.2 2.2 1 1 1 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein F-box-like PF12937.7 ORY52836.1 - 0.025 14.5 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like Med31 PF05669.12 ORY52837.1 - 6.1e-31 106.3 1.6 7.6e-31 106.0 1.6 1.1 1 0 0 1 1 1 1 SOH1 zf-MYND PF01753.18 ORY52839.1 - 3.7e-09 36.5 9.3 3.7e-09 36.5 9.3 2.0 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 ORY52839.1 - 0.088 12.7 3.4 0.31 10.9 3.4 1.9 1 0 0 1 1 1 0 HIT zinc finger Response_reg PF00072.24 ORY53382.1 - 2.3e-20 72.8 0.1 7.4e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ORY53382.1 - 1.3e-18 67.5 0.0 2.4e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 ORY53382.1 - 1.7e-12 47.5 0.0 2.6e-05 24.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 ORY53382.1 - 1.1e-08 35.0 0.2 8.9e-08 32.1 0.2 2.5 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY53382.1 - 5.9e-08 32.9 0.0 0.0077 16.5 0.0 3.1 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 ORY53382.1 - 7.5e-05 22.7 0.1 0.54 10.4 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 ORY53382.1 - 0.00029 20.8 0.0 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ORY53382.1 - 0.063 13.5 0.0 2.3 8.5 0.0 3.0 3 0 0 3 3 3 0 PAS domain PAS_7 PF12860.7 ORY53382.1 - 0.072 13.3 0.6 31 4.8 0.0 3.5 4 0 0 4 4 4 0 PAS fold HemY_N PF07219.13 ORY53382.1 - 0.11 12.7 1.6 0.3 11.3 0.1 2.2 2 0 0 2 2 2 0 HemY protein N-terminus RNA_pol_Rpb6 PF01192.22 ORY53383.1 - 5.9e-18 64.5 0.1 9.5e-18 63.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_6 PF13405.6 ORY53384.1 - 7.5e-14 50.4 0.2 1.2e-06 28.0 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY53384.1 - 3.7e-13 48.0 0.9 0.00015 21.0 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 ORY53384.1 - 3.9e-13 49.7 0.3 5.9e-06 26.6 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORY53384.1 - 1.3e-09 37.8 0.6 0.05 13.5 0.2 3.9 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORY53384.1 - 6.8e-06 25.3 0.1 0.012 15.1 0.2 2.9 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 ORY53384.1 - 0.0041 18.0 0.0 0.0071 17.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 ORY53384.1 - 0.041 13.8 0.1 0.34 10.9 0.0 2.3 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY53384.1 - 0.045 14.1 0.0 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain DUF3591 PF12157.8 ORY53385.1 - 3.3e-182 606.1 0.1 4.8e-182 605.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 ORY53385.1 - 0.012 15.4 2.2 0.033 14.0 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 ORY53385.1 - 0.4 10.9 1.7 0.69 10.1 1.7 1.3 1 0 0 1 1 1 0 Zinc knuckle F-box-like PF12937.7 ORY53386.1 - 0.00044 20.1 0.3 0.00094 19.0 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY53386.1 - 0.051 13.5 1.8 0.11 12.4 0.6 2.2 2 1 0 2 2 2 0 F-box domain BET PF17035.5 ORY53386.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Ccdc124 PF06244.12 ORY53387.1 - 8.8e-06 26.3 0.5 9.9e-06 26.1 0.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DSRB PF10781.9 ORY53387.1 - 0.17 11.5 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Dextransucrase DSRB AA_permease PF00324.21 ORY53388.1 - 4e-130 434.6 41.5 5e-130 434.3 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY53388.1 - 3.3e-31 108.6 42.6 4.1e-31 108.3 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease Alg14 PF08660.11 ORY53389.1 - 2.9e-53 180.4 0.0 4e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like GntR PF00392.21 ORY53389.1 - 0.054 13.2 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HLH PF00010.26 ORY53390.1 - 5.3e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.32 ORY53391.1 - 1.1e-15 57.7 13.6 0.00013 22.7 0.3 6.9 7 1 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 ORY53391.1 - 0.00034 19.3 1.6 0.018 13.6 0.2 3.0 3 0 0 3 3 3 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 ORY53391.1 - 0.0012 19.1 0.0 0.09 13.1 0.0 3.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WRNPLPNID PF15017.6 ORY53391.1 - 0.0067 17.3 1.0 0.0067 17.3 1.0 2.3 2 0 0 2 2 2 1 Putative WW-binding domain and destruction box WD40_like PF17005.5 ORY53391.1 - 0.066 12.5 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain AMH_N PF04709.12 ORY53391.1 - 0.16 10.8 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Herpes_LMP2 PF07415.11 ORY53391.1 - 0.29 9.9 1.5 0.44 9.3 1.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein PTPRCAP PF15713.5 ORY53391.1 - 2.6 8.3 10.2 0.043 14.1 2.1 2.0 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CobT PF06213.12 ORY53391.1 - 8.7 5.6 9.5 0.12 11.7 0.8 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Sec63 PF02889.16 ORY53393.1 - 3.9e-20 72.1 0.0 8.2e-20 71.0 0.0 1.5 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.31 ORY53393.1 - 2.6e-17 62.7 0.3 5.3e-17 61.7 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain AA_permease PF00324.21 ORY53394.1 - 1.6e-129 432.6 45.9 2e-129 432.3 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY53394.1 - 5.2e-37 127.7 47.7 6.6e-37 127.4 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease WTF PF03303.13 ORY53394.1 - 2.9 7.5 8.5 4.2 7.0 6.6 2.1 2 0 0 2 2 2 0 WTF protein Ccdc124 PF06244.12 ORY53395.1 - 1.4e-05 25.7 0.2 1.4e-05 25.6 0.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DSRB PF10781.9 ORY53395.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Dextransucrase DSRB F-box-like PF12937.7 ORY53396.1 - 0.00051 19.9 0.1 0.0013 18.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY53396.1 - 0.0015 18.3 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain Radical_SAM PF04055.21 ORY53397.1 - 2e-12 47.8 0.0 2.8e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Dendrin PF15498.6 ORY53398.1 - 0.043 12.6 1.0 0.056 12.2 1.0 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin PHTB1_C PF14728.6 ORY53399.1 - 0.23 10.5 0.0 0.23 10.5 0.0 1.4 2 0 0 2 2 2 0 PTHB1 C-terminus COPI_C PF06957.11 ORY53399.1 - 3.9 6.1 5.9 4.7 5.9 5.9 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Hap4_Hap_bind PF10297.9 ORY53400.1 - 3.1e-08 33.5 7.7 9.2e-08 32.0 7.7 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 ORY53400.1 - 9.2e-08 32.1 5.3 4.3e-07 29.9 1.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY53400.1 - 0.036 14.2 8.2 0.13 12.4 2.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Metal_resist PF13801.6 ORY53400.1 - 4.8 7.4 12.8 0.92 9.7 3.3 2.6 2 1 0 2 2 2 0 Heavy-metal resistance Cu-oxidase_2 PF07731.14 ORY53401.1 - 1.7e-40 137.9 5.4 1e-37 129.0 1.7 3.2 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 ORY53401.1 - 8.9e-37 126.7 4.1 3.7e-32 111.6 0.8 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY53401.1 - 6.2e-21 74.6 4.9 2.3e-17 63.1 0.3 4.4 4 1 0 5 5 5 2 Multicopper oxidase F-box-like PF12937.7 ORY53402.1 - 1.7e-05 24.6 0.4 3.8e-05 23.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY53402.1 - 6.5e-05 22.7 0.1 0.00018 21.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF3669 PF12417.8 ORY53402.1 - 0.13 12.5 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Zinc finger protein MT-A70 PF05063.14 ORY53403.1 - 7.7e-20 71.5 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 MT-A70 LPD13 PF18825.1 ORY53403.1 - 1.5 8.6 6.4 5.2 6.8 0.7 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 13 Suf PF05843.14 ORY53977.1 - 1.7e-71 241.6 0.8 1.1e-68 232.4 0.0 3.9 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY53977.1 - 1.4e-10 41.0 10.2 0.58 11.1 0.2 8.1 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY53977.1 - 1.2e-05 25.8 1.2 2.4 8.7 0.1 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY53977.1 - 0.00016 21.0 2.7 0.0017 17.6 0.7 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY53977.1 - 0.0011 19.1 4.4 0.074 13.2 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat HAT PF02184.16 ORY53977.1 - 0.0012 18.8 0.5 0.023 14.6 0.0 2.9 3 0 0 3 3 3 1 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 ORY53977.1 - 0.078 13.6 0.0 0.078 13.6 0.0 7.7 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY53977.1 - 0.29 11.4 3.6 12 6.4 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY53977.1 - 0.4 11.4 17.1 0.76 10.5 0.1 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY53977.1 - 6.3 7.2 15.6 4.9 7.5 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR_3 PF13812.6 ORY53978.1 - 0.12 12.5 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain BTB_2 PF02214.22 ORY53979.1 - 9.8e-06 25.8 0.2 1.8e-05 25.0 0.2 1.4 1 1 0 1 1 1 1 BTB/POZ domain zf-MYND PF01753.18 ORY53982.1 - 1.3e-10 41.2 12.8 2.2e-10 40.4 12.8 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY53982.1 - 0.089 12.9 9.1 0.18 11.9 9.1 1.5 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 BAR PF03114.18 ORY53983.1 - 1.7e-43 149.0 0.0 2e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 BAR domain BTB_2 PF02214.22 ORY53984.1 - 0.0002 21.6 0.0 0.0011 19.3 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain G10 PF01125.17 ORY53985.1 - 3.6e-67 224.7 5.8 4e-67 224.5 5.8 1.0 1 0 0 1 1 1 1 G10 protein zf-C3HC4_4 PF15227.6 ORY53985.1 - 0.36 11.0 9.6 0.24 11.6 1.3 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Ribosomal_S15 PF00312.22 ORY53986.1 - 1.5e-27 95.6 1.4 2.1e-27 95.1 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 SR-25 PF10500.9 ORY53986.1 - 0.49 10.0 10.3 0.11 12.1 6.9 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SlyX PF04102.12 ORY53988.1 - 1.4 9.6 5.0 7.5 7.3 5.0 2.2 1 1 0 1 1 1 0 SlyX 4HBT PF03061.22 ORY53989.1 - 0.14 12.5 0.2 3.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Thioesterase superfamily Abhydrolase_3 PF07859.13 ORY53990.1 - 4.7e-19 69.1 0.0 5.3e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY53990.1 - 3.8e-11 42.9 0.0 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ORY53990.1 - 2.2e-06 27.4 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 ORY53990.1 - 5e-06 25.6 0.0 7.8e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S15 PF02129.18 ORY53990.1 - 3.3e-05 23.6 0.0 9e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.11 ORY53990.1 - 8.3e-05 21.8 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DUF2920 PF11144.8 ORY53990.1 - 0.0078 15.4 0.0 0.36 10.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.16 ORY53990.1 - 0.016 15.0 0.0 6.6 6.5 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.8 ORY53990.1 - 0.03 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORY53990.1 - 0.06 12.6 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORY53990.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) COesterase PF00135.28 ORY53990.1 - 0.18 10.6 0.0 0.74 8.6 0.0 1.8 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_1 PF00561.20 ORY53990.1 - 1.8 8.1 3.7 33 4.0 4.2 2.5 2 1 0 2 2 2 0 alpha/beta hydrolase fold Epimerase PF01370.21 ORY53991.1 - 9.2e-12 44.9 0.2 3.4e-11 43.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY53991.1 - 2.9e-08 33.0 0.0 3.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY53991.1 - 2e-07 31.1 2.3 3.3e-07 30.4 2.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY53991.1 - 1.6e-06 27.5 0.4 7.1e-05 22.1 0.4 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY53991.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY53991.1 - 0.0025 17.3 0.4 0.043 13.3 0.3 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ORY53991.1 - 0.004 16.3 0.2 0.0055 15.9 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY53991.1 - 0.01 15.4 0.5 0.016 14.7 0.5 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 ORY53991.1 - 0.089 11.9 0.1 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Sugar_tr PF00083.24 ORY53992.1 - 1.4e-110 370.3 21.6 2.4e-110 369.5 21.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY53992.1 - 5e-27 94.7 51.0 8e-17 61.2 17.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF5381 PF17353.2 ORY53992.1 - 1.1 9.0 4.1 1.9 8.2 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5381) DPBB_1 PF03330.18 ORY53993.1 - 1.3e-06 28.6 0.2 3.1e-06 27.4 0.2 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY53993.1 - 0.00043 20.1 1.9 0.00048 20.0 0.6 1.8 1 1 0 1 1 1 1 Barwin family SOG2 PF10428.9 ORY53993.1 - 1.4 8.0 16.4 1.5 7.9 16.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ATF7IP_BD PF16788.5 ORY53993.1 - 6.3 6.8 10.8 9.5 6.3 10.8 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain TB2_DP1_HVA22 PF03134.19 ORY53994.1 - 4.7e-10 39.3 0.1 8.1e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family IDO PF01231.18 ORY53995.1 - 9.1e-120 400.4 0.0 1.1e-119 400.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase BTB_2 PF02214.22 ORY53996.1 - 0.0032 17.8 0.1 0.014 15.7 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain Methyltransf_16 PF10294.9 ORY53997.1 - 5.3e-12 45.8 0.0 9.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase DUF4567 PF15131.6 ORY53997.1 - 0.066 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) DUF866 PF05907.13 ORY53998.1 - 9.3e-59 197.8 2.7 1.1e-58 197.6 2.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) NPCBM_assoc PF10633.9 ORY53998.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase zinc_ribbon_12 PF11331.8 ORY53998.1 - 0.39 10.6 0.1 0.39 10.6 0.1 2.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain Elf1 PF05129.13 ORY53998.1 - 0.73 9.9 4.2 2.6 8.1 1.0 2.7 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like Zn_ribbon_SprT PF17283.2 ORY53998.1 - 0.79 9.7 6.7 0.91 9.5 2.4 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Fer4_10 PF13237.6 ORY53998.1 - 1.7 8.8 5.1 1 9.6 0.3 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Cut8 PF08559.10 ORY53999.1 - 1.6e-13 50.9 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DIL PF01843.19 ORY54000.1 - 4.5e-31 107.2 3.0 8.3e-31 106.4 3.0 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 ORY54000.1 - 1.1e-09 38.8 0.0 3.3e-08 34.0 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY54000.1 - 3.1e-09 36.9 0.1 7.8e-07 29.3 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY54000.1 - 5.9e-09 36.3 0.0 5e-06 27.0 0.0 3.6 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY54000.1 - 1.3e-07 31.3 0.0 0.0048 17.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 ORY54000.1 - 6.9e-05 23.1 0.1 0.0037 17.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat BTB_2 PF02214.22 ORY54001.1 - 0.0012 19.1 0.1 0.0041 17.4 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain zf-CCHC PF00098.23 ORY54071.1 - 0.048 13.7 0.5 0.092 12.9 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Dimer_Tnp_hAT PF05699.14 ORY54072.1 - 0.00018 21.2 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ferrochelatase PF00762.19 ORY54072.1 - 0.077 12.1 0.2 0.13 11.3 0.1 1.4 1 1 0 1 1 1 0 Ferrochelatase YABBY PF04690.13 ORY54072.1 - 0.11 13.1 0.3 0.2 12.2 0.3 1.4 1 0 0 1 1 1 0 YABBY protein FANCF PF11107.8 ORY54073.1 - 0.0099 15.1 1.2 0.012 14.9 1.2 1.1 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) RrnaAD PF00398.20 ORY54076.1 - 8.3e-64 215.2 0.0 1.1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 ORY54076.1 - 3e-07 31.0 0.0 5.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY54076.1 - 1.2e-05 25.8 0.0 2.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY54076.1 - 0.00048 20.8 0.0 0.00084 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY54076.1 - 0.0012 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ORY54076.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY54076.1 - 0.0072 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 ORY54076.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 ORY54076.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 ORY54076.1 - 0.073 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CMAS PF02353.20 ORY54076.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Adaptin_N PF01602.20 ORY54077.1 - 1.8e-141 472.3 4.8 2.1e-141 472.1 4.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY54077.1 - 4.6e-61 205.6 3.0 4.3e-60 202.4 0.3 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY54077.1 - 5e-14 52.4 11.6 2.3e-05 24.7 0.0 6.5 3 2 4 7 7 7 4 HEAT repeats HEAT PF02985.22 ORY54077.1 - 1.1e-09 37.8 6.5 0.029 14.6 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 ORY54077.1 - 0.00012 22.5 6.0 2.1 8.9 0.1 6.3 5 2 1 6 6 6 2 HEAT-like repeat RTP1_C1 PF10363.9 ORY54077.1 - 0.00029 21.0 2.2 6.1 7.1 0.0 4.9 3 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 ORY54077.1 - 0.002 17.4 0.1 0.02 14.1 0.0 2.3 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 ORY54077.1 - 0.0035 16.9 0.0 0.38 10.3 0.0 2.9 2 1 0 2 2 2 1 CLASP N terminal Sec7_N PF12783.7 ORY54077.1 - 0.043 13.7 0.7 0.76 9.7 0.0 2.9 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CAAP1 PF15335.6 ORY54077.1 - 0.1 13.1 0.1 0.31 11.6 0.1 1.8 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 EABR PF12180.8 ORY54077.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Arm PF00514.23 ORY54077.1 - 8.6 6.6 11.7 18 5.6 0.0 5.7 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat PTP_tm PF18861.1 ORY54078.1 - 0.0089 16.0 0.5 0.042 13.9 0.0 2.0 2 1 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 ORY54078.1 - 0.031 14.9 2.9 0.031 14.9 2.9 2.3 1 1 2 3 3 3 0 Small Novel Rich in Cartilage Amnionless PF14828.6 ORY54078.1 - 0.034 13.0 0.2 0.12 11.2 0.0 1.8 1 1 0 2 2 2 0 Amnionless VSP PF03302.13 ORY54078.1 - 0.16 10.8 8.4 0.013 14.3 3.2 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein SPC22 PF04573.12 ORY54080.1 - 1.5e-50 171.0 0.1 1.9e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF747 PF05346.11 ORY54081.1 - 4.8e-117 391.0 0.3 6.2e-117 390.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Sec31 PF11549.8 ORY54082.1 - 0.1 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein transport protein SEC31 PRANC PF09372.10 ORY54083.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Sec31 PF11549.8 ORY54083.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 DUF416 PF04222.12 ORY54083.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF416) APC1_C PF18122.1 ORY54085.1 - 1.2e-18 67.7 0.0 2.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 ORY54085.1 - 2.7e-08 34.4 1.0 2.7e-08 34.4 1.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 ORY54085.1 - 0.85 10.2 22.3 12 6.6 0.0 6.3 7 0 0 7 7 7 0 Proteasome/cyclosome repeat PRANC PF09372.10 ORY54086.1 - 0.099 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 PRANC domain LRR_4 PF12799.7 ORY54086.1 - 0.26 11.8 2.5 11 6.6 0.0 3.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Got1 PF04178.12 ORY54087.1 - 6.6e-20 71.6 0.8 7.5e-20 71.4 0.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family ThiW PF09512.10 ORY54087.1 - 0.0041 17.2 0.8 0.0048 17.0 0.8 1.2 1 0 0 1 1 1 1 Thiamine-precursor transporter protein (ThiW) UQ_con PF00179.26 ORY54146.1 - 1.1e-17 63.9 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY54146.1 - 0.17 12.2 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF1275 PF06912.11 ORY54147.1 - 1.9e-20 73.6 13.2 2.4e-20 73.3 13.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.16 ORY54147.1 - 0.053 12.4 24.3 0.022 13.7 5.5 2.7 2 1 1 3 3 3 0 Major Facilitator Superfamily Acyl_transf_3 PF01757.22 ORY54147.1 - 0.08 12.0 8.9 0.012 14.7 4.8 1.6 1 1 0 1 1 1 0 Acyltransferase family Phage_holin_5_2 PF16079.5 ORY54147.1 - 0.22 11.9 2.0 17 5.9 0.0 2.8 3 0 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V fn3 PF00041.21 ORY54148.1 - 0.027 14.8 0.1 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type III domain TraF_2 PF13729.6 ORY54148.1 - 0.15 11.4 0.7 0.28 10.5 0.7 1.4 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein FliT PF05400.13 ORY54148.1 - 0.41 11.5 0.1 0.41 11.5 0.1 3.5 2 1 1 3 3 3 0 Flagellar protein FliT FlxA PF14282.6 ORY54148.1 - 0.61 10.1 6.7 0.25 11.3 0.8 2.8 2 0 0 2 2 2 0 FlxA-like protein Activator-TraM PF11657.8 ORY54148.1 - 2.2 8.1 7.6 0.56 10.0 1.7 2.2 2 0 0 2 2 2 0 Transcriptional activator TraM Fib_alpha PF08702.10 ORY54148.1 - 2.5 8.3 8.1 3.1 8.0 2.9 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CLP1_P PF16575.5 ORY54149.1 - 7.9e-37 126.9 0.0 3.3e-35 121.6 0.0 2.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 ORY54149.1 - 0.0026 17.8 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY54149.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ORY54149.1 - 0.13 12.6 0.0 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SHMT PF00464.19 ORY54150.1 - 1.8e-172 573.4 0.0 2.2e-172 573.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 ORY54150.1 - 0.00013 21.4 0.1 0.00091 18.6 0.1 2.1 1 1 0 1 1 1 1 Beta-eliminating lyase DUF4142 PF13628.6 ORY54150.1 - 0.073 13.3 2.5 8.6 6.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4142) Coq4 PF05019.13 ORY54152.1 - 2.3e-91 305.1 0.0 2.7e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 HA2 PF04408.23 ORY54153.1 - 2.2e-21 76.2 0.0 2.2e-21 76.2 0.0 4.0 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY54153.1 - 2e-17 63.3 0.0 5.6e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY54153.1 - 1.7e-14 54.1 0.0 4.1e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY54153.1 - 4.2e-05 23.4 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY54153.1 - 0.00061 19.6 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY54153.1 - 0.001 18.2 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY54153.1 - 0.0034 17.6 0.1 0.017 15.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain CDC27 PF09507.10 ORY54153.1 - 0.67 9.3 31.2 1.4 8.2 31.2 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Period_C PF12114.8 ORY54153.1 - 0.87 9.1 8.6 1.7 8.2 8.6 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Methyltr_RsmB-F PF01189.17 ORY54154.1 - 5.8e-33 114.2 0.0 6.2e-27 94.6 0.0 4.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Sigma70_ner PF04546.13 ORY54155.1 - 0.17 11.8 0.9 0.28 11.1 0.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region LRR_4 PF12799.7 ORY54155.1 - 1.5 9.4 10.6 0.69 10.4 1.7 3.7 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) RPN1_RPN2_N PF17781.1 ORY54156.1 - 6.6e-116 387.0 0.0 1.4e-115 386.0 0.0 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 ORY54156.1 - 4.1e-28 97.2 0.1 1.9e-27 95.1 0.0 2.1 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 ORY54156.1 - 2.3e-25 87.7 15.7 6.6e-06 26.3 0.3 8.4 7 0 0 7 7 7 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORY54156.1 - 7.4e-07 29.5 1.0 0.028 14.8 0.0 3.7 3 1 1 4 4 4 3 HEAT repeats ATP19 PF11022.8 ORY54157.1 - 1.6e-19 70.0 0.1 1.8e-19 69.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Oxidored-like PF09791.9 ORY54158.1 - 1.2e-17 63.3 0.9 2.3e-17 62.4 0.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal RDM PF11002.8 ORY54158.1 - 0.071 13.1 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 RFPL defining motif (RDM) DEAD PF00270.29 ORY54160.1 - 1.5e-35 122.5 0.0 1.1e-34 119.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY54160.1 - 2.4e-20 72.9 0.1 6e-20 71.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DAO PF01266.24 ORY54161.1 - 6.9e-31 108.1 0.3 7.9e-31 107.9 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY54161.1 - 0.00026 20.2 0.0 0.00039 19.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY54161.1 - 0.00096 19.7 0.2 0.023 15.2 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY54161.1 - 0.0049 16.2 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY54161.1 - 0.0059 15.9 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 ORY54161.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 ORY54161.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 ORY54161.1 - 0.023 15.1 0.0 0.033 14.6 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ORY54161.1 - 0.033 14.4 0.4 0.091 13.0 0.4 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY54161.1 - 0.044 13.0 0.1 0.097 11.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 ORY54161.1 - 0.05 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ORY54161.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ORY54161.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MaoC_dehydrat_N PF13452.6 ORY54162.1 - 1.4e-05 25.2 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 ORY54162.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain Cytochrom_C PF00034.21 ORY54163.1 - 8.7e-11 42.8 0.1 1.2e-10 42.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORY54163.1 - 1.4e-08 34.9 1.9 8.8e-08 32.4 1.9 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORY54163.1 - 0.00043 20.0 0.3 0.0075 16.0 0.1 2.1 2 0 0 2 2 2 1 Cytochrome c-550 domain CCP_MauG PF03150.14 ORY54163.1 - 0.039 14.6 0.0 0.041 14.5 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase ADH_N PF08240.12 ORY54164.1 - 2.6e-30 104.5 0.6 6.9e-30 103.2 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY54164.1 - 9.2e-22 77.4 1.7 1.6e-21 76.7 1.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY54164.1 - 1.3e-06 29.5 0.7 2.4e-06 28.6 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY54164.1 - 3.8e-05 23.3 1.4 6.4e-05 22.5 1.4 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 ORY54164.1 - 0.00061 20.1 0.6 0.0011 19.2 0.6 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY54164.1 - 0.0022 18.1 0.6 0.0044 17.1 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ORY54164.1 - 0.019 14.2 0.5 0.031 13.5 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 ORY54164.1 - 0.02 15.3 0.4 0.039 14.4 0.4 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_N_2 PF16884.5 ORY54164.1 - 0.038 13.9 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 ORY54164.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ORY54164.1 - 0.48 9.5 3.8 0.18 10.9 1.6 1.4 2 0 0 2 2 2 0 FAD binding domain Aminotran_1_2 PF00155.21 ORY54165.1 - 5.9e-42 144.1 0.0 8.3e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY54165.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Chlam_vir PF05475.11 ORY54166.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Pgp3 C-terminal domain Neuralized PF07177.12 ORY54166.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Neuralized Frag1 PF10277.9 ORY54167.1 - 2.7e-26 92.4 9.0 3.2e-26 92.2 9.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Dicty_REP PF05086.12 ORY54168.1 - 3.3 5.6 3.6 4.7 5.1 3.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.14 ORY54168.1 - 6.6 4.9 7.4 8.2 4.6 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_5 PF07728.14 ORY54170.1 - 4.8e-67 224.2 0.0 5e-30 104.3 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY54170.1 - 1.9e-05 25.1 0.3 0.21 12.0 0.0 4.3 4 1 0 4 4 4 1 AAA ATPase domain VWA PF00092.28 ORY54170.1 - 0.00014 22.1 0.0 0.00026 21.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_2 PF07724.14 ORY54170.1 - 0.0056 16.8 0.0 0.38 10.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RsgA_GTPase PF03193.16 ORY54170.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 ORY54170.1 - 0.027 13.9 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORY54170.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region VWA_2 PF13519.6 ORY54170.1 - 0.031 14.9 0.0 0.12 13.0 0.0 2.1 1 1 1 2 2 2 0 von Willebrand factor type A domain RNA_pol_Rpb5_C PF01191.19 ORY54170.1 - 0.092 12.6 0.0 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain AAA PF00004.29 ORY54170.1 - 0.17 12.3 0.0 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) vATP-synt_E PF01991.18 ORY54171.1 - 9.2e-59 198.2 17.3 1.1e-58 198.0 17.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Cwf_Cwc_15 PF04889.12 ORY54259.1 - 0.0012 18.6 2.6 0.0012 18.6 2.6 2.3 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein CwfJ_C_1 PF04677.15 ORY54261.1 - 1.6e-28 99.0 0.0 8.6e-28 96.7 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 ORY54261.1 - 2.4e-11 44.4 0.0 4.4e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.6 ORY54261.1 - 1e-09 38.0 5.3 1e-09 38.0 5.3 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 ORY54261.1 - 0.0025 17.8 1.1 0.0063 16.5 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 ORY54261.1 - 0.33 11.0 1.5 0.82 9.7 1.3 1.7 2 0 0 2 2 2 0 Zinc knuckle Rep_fac-A_C PF08646.10 ORY54262.1 - 1.2e-51 174.3 0.9 1.6e-49 167.4 0.3 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 ORY54262.1 - 1.8e-33 114.4 0.1 4.9e-33 113.0 0.2 1.7 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 ORY54262.1 - 6.5e-23 80.7 0.0 1.2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 ORY54262.1 - 1.8e-10 40.7 0.2 9.1e-09 35.2 0.0 2.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Peptidase_M16_M PF16187.5 ORY54262.1 - 0.048 13.0 0.3 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 Middle or third domain of peptidase_M16 Peptidase_M16_M PF16187.5 ORY54263.1 - 1.1e-79 267.7 0.1 2.1e-79 266.7 0.0 1.5 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORY54263.1 - 2.8e-36 124.7 0.2 1.3e-35 122.6 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY54263.1 - 2.3e-25 89.7 0.3 5.4e-14 52.6 0.0 3.8 4 0 0 4 4 4 2 Peptidase M16 inactive domain EcoEI_R_C PF08463.10 ORY54263.1 - 0.011 15.9 0.3 0.047 13.8 0.0 2.1 2 0 0 2 2 2 0 EcoEI R protein C-terminal ArdA PF07275.11 ORY54263.1 - 0.19 12.3 2.7 2.1 8.9 0.0 3.2 4 0 0 4 4 4 0 Antirestriction protein (ArdA) DUF604 PF04646.12 ORY54264.1 - 2.2e-21 76.4 0.0 3.4e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 ORY54264.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DEC-1_N PF04625.13 ORY54268.1 - 0.04 12.9 5.3 0.045 12.8 5.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region LETM1 PF07766.13 ORY54269.1 - 1.8e-104 348.8 2.4 1.8e-104 348.8 2.4 2.7 3 0 0 3 3 3 1 LETM1-like protein EF-hand_7 PF13499.6 ORY54269.1 - 0.00013 22.3 1.6 0.006 17.0 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair ZapB PF06005.12 ORY54269.1 - 0.0027 18.1 2.1 0.0027 18.1 2.1 4.2 2 1 0 2 2 2 1 Cell division protein ZapB EF-hand_9 PF14658.6 ORY54269.1 - 0.016 15.5 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain CAML PF14963.6 ORY54269.1 - 2.9 8.0 11.5 7.2 6.7 11.5 1.6 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand WRNPLPNID PF15017.6 ORY54270.1 - 2.3 9.1 7.9 4.7 8.2 3.8 2.9 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Pkinase PF00069.25 ORY54272.1 - 1.7e-21 76.8 0.0 2.9e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY54272.1 - 1.9e-16 60.1 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mucin PF01456.17 ORY54275.1 - 0.049 13.6 10.3 0.13 12.3 10.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 ORY54275.1 - 3.1 5.9 10.2 5.7 5.0 10.2 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPP1 PF10341.9 ORY54279.1 - 0.078 13.0 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD Inv-AAD PF18785.1 ORY54282.1 - 3.8e-32 110.9 0.2 8.3e-32 109.8 0.2 1.5 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ORY54282.1 - 7.9e-18 64.2 0.1 1.1e-17 63.8 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY54282.1 - 0.0084 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 ORY54282.1 - 0.044 13.7 0.0 0.058 13.3 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC3 PF18771.1 ORY54282.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 Sterol-sensing PF12349.8 ORY54283.1 - 4.8e-31 107.7 7.4 8.7e-31 106.8 7.4 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ORY54283.1 - 1.6e-12 46.4 0.5 2.3e-12 45.9 0.5 1.1 1 0 0 1 1 1 1 Patched family Gemini_mov PF01708.16 ORY54283.1 - 0.062 13.1 0.0 0.37 10.6 0.0 2.3 1 0 0 1 1 1 0 Geminivirus putative movement protein PKD_channel PF08016.12 ORY54360.1 - 0.0017 17.1 0.8 0.0023 16.7 0.8 1.2 1 0 0 1 1 1 1 Polycystin cation channel Inositol_P PF00459.25 ORY54361.1 - 2.6e-55 187.9 0.2 5.2e-55 186.9 0.2 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family DUF4744 PF15918.5 ORY54362.1 - 0.073 13.9 0.0 0.14 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Tox-PL-2 PF15643.6 ORY54363.1 - 0.021 14.9 0.0 0.094 12.8 0.0 1.9 2 0 0 2 2 2 0 Papain fold toxin 2 vWA-TerF-like PF10138.9 ORY54364.1 - 5.4e-05 23.4 0.1 7.6e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 ORY54364.1 - 0.0086 16.3 0.5 0.023 14.9 0.5 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF433 PF04255.14 ORY54364.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) S4 PF01479.25 ORY54365.1 - 4.2e-11 42.4 1.3 4.2e-11 42.4 1.3 2.9 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 ORY54365.1 - 4e-06 27.6 0.4 1.1e-05 26.2 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain NST1 PF13945.6 ORY54366.1 - 1.7e-42 145.7 0.0 1.7e-42 145.7 0.0 6.3 6 1 1 7 7 7 2 Salt tolerance down-regulator RNA_pol_3_Rpc31 PF11705.8 ORY54366.1 - 0.0027 18.0 8.9 0.0027 18.0 8.9 7.6 5 2 0 5 5 5 2 DNA-directed RNA polymerase III subunit Rpc31 AhpC-TSA_2 PF13911.6 ORY54367.1 - 1e-10 41.7 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ORY54367.1 - 1.7e-05 24.7 0.0 5.2e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY54367.1 - 2.3e-05 24.1 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin DUF89 PF01937.19 ORY54368.1 - 7.1e-109 364.0 0.0 8.2e-109 363.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 COG4 PF08318.12 ORY54368.1 - 0.11 11.5 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 COG4 transport protein IATP PF04568.12 ORY54369.1 - 3.3e-10 40.3 7.2 4.6e-10 39.8 7.2 1.3 1 1 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Fib_alpha PF08702.10 ORY54369.1 - 0.013 15.7 0.2 0.013 15.7 0.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4140 PF13600.6 ORY54369.1 - 0.085 13.3 5.7 0.11 12.9 5.6 1.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF5339 PF17274.2 ORY54369.1 - 0.1 13.4 4.8 0.13 13.1 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5339) DUF4732 PF15876.5 ORY54369.1 - 0.2 11.7 0.7 11 6.1 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4732) DUF1476 PF07345.11 ORY54369.1 - 0.21 12.0 5.8 0.38 11.1 5.4 1.7 1 1 0 1 1 1 0 ATPase inhibitor subunit zeta ATP_sub_h PF10775.9 ORY54370.1 - 9.9e-19 67.1 3.3 1.8e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 ATP synthase complex subunit h Gaa1 PF04114.14 ORY54371.1 - 1.2e-108 364.4 0.0 1.4e-108 364.1 0.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PRA1 PF03208.19 ORY54371.1 - 0.034 13.8 0.4 0.11 12.1 0.4 1.8 1 0 0 1 1 1 0 PRA1 family protein DUF962 PF06127.11 ORY54373.1 - 0.16 12.0 0.6 6.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF962) Ion_trans PF00520.31 ORY54375.1 - 1.6e-06 27.6 13.8 3.1e-06 26.6 13.8 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ORY54375.1 - 0.02 13.6 11.2 0.46 9.1 11.2 2.2 1 1 0 1 1 1 0 Polycystin cation channel DPM3 PF08285.11 ORY54375.1 - 5 7.4 6.4 1.1 9.5 0.7 3.0 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Piwi PF02171.17 ORY54376.1 - 7.8e-59 199.4 0.0 1.5e-58 198.5 0.0 1.4 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 ORY54376.1 - 1.2e-13 50.4 0.0 3e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 ORY54376.1 - 4e-13 49.3 0.0 8.3e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 ORY54376.1 - 1.9e-10 41.5 0.0 4.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 ORY54376.1 - 0.0063 16.8 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 Mid domain of argonaute ArgoL2 PF16488.5 ORY54376.1 - 0.059 13.7 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Argonaute linker 2 domain Adap_comp_sub PF00928.21 ORY54377.1 - 1.8e-18 66.9 0.0 2.6e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY54377.1 - 0.0029 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4337 PF14235.6 ORY54377.1 - 0.3 11.2 1.8 0.56 10.3 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Med7 PF05983.11 ORY54379.1 - 2.3e-48 164.8 0.1 4.2e-48 164.0 0.1 1.4 1 0 0 1 1 1 1 MED7 protein DUF3138 PF11336.8 ORY54379.1 - 0.13 10.9 4.2 0.17 10.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.19 ORY54379.1 - 2.6 8.7 9.0 3 8.5 2.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein PTPLA PF04387.14 ORY54381.1 - 6.8e-44 149.5 10.1 6.8e-44 149.5 10.1 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Gp138_N PF18352.1 ORY54381.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain Med7 PF05983.11 ORY54382.1 - 7.6e-49 166.4 0.1 1.3e-48 165.7 0.1 1.4 1 0 0 1 1 1 1 MED7 protein DUF3138 PF11336.8 ORY54382.1 - 0.15 10.6 3.9 0.2 10.2 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.19 ORY54382.1 - 0.35 11.5 10.2 1.4 9.5 2.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Acyltransferase PF01553.21 ORY54383.1 - 2e-15 56.6 0.0 3.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase FA_desaturase PF00487.24 ORY54383.1 - 0.037 13.8 3.4 0.067 13.0 3.4 1.4 1 0 0 1 1 1 0 Fatty acid desaturase TauD PF02668.16 ORY54463.1 - 2.7e-21 76.6 0.0 3.5e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ORY54464.1 - 3.5e-27 95.3 22.0 3.5e-27 95.3 22.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY54464.1 - 0.00016 20.2 3.8 0.00029 19.4 3.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pyr_redox_2 PF07992.14 ORY54466.1 - 4.4e-29 101.6 0.4 1.4e-28 99.9 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY54466.1 - 1.1e-10 41.9 1.0 3.8e-07 30.6 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY54466.1 - 5.6e-07 28.8 5.1 0.029 13.2 0.6 3.1 2 1 1 3 3 3 3 Tryptophan halogenase DAO PF01266.24 ORY54466.1 - 5.1e-06 26.3 5.0 0.0077 15.9 0.1 3.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY54466.1 - 0.00035 19.9 0.0 0.0028 16.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY54466.1 - 0.0013 18.9 0.5 0.083 13.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY54466.1 - 0.0028 16.8 0.0 0.057 12.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORY54466.1 - 0.0035 17.3 3.0 6.5 6.7 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 ORY54466.1 - 0.0042 17.3 0.8 1.4 9.2 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain NAD_binding_7 PF13241.6 ORY54466.1 - 0.011 16.2 0.2 5.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Catalase_C PF18011.1 ORY54466.1 - 0.018 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases Lycopene_cycl PF05834.12 ORY54466.1 - 0.24 10.4 3.6 3.5 6.6 0.0 3.0 3 1 1 4 4 4 0 Lycopene cyclase protein bZIP_1 PF00170.21 ORY54467.1 - 3.9e-07 30.1 11.6 1.1e-06 28.6 11.6 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY54467.1 - 1.5e-05 24.9 16.5 1.5e-05 24.9 16.5 1.9 2 0 0 2 2 2 1 Basic region leucine zipper Pox_A_type_inc PF04508.12 ORY54467.1 - 0.001 18.8 1.1 0.0023 17.7 0.0 2.2 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat TSC22 PF01166.18 ORY54467.1 - 0.017 15.4 0.3 0.049 14.0 0.1 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 ORY54467.1 - 0.021 15.3 11.8 0.021 15.3 11.8 2.4 1 1 2 3 3 3 0 bZIP Maf transcription factor YabA PF06156.13 ORY54467.1 - 0.05 14.2 1.2 0.09 13.4 1.2 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF4570 PF15134.6 ORY54467.1 - 0.076 13.0 5.0 0.15 12.1 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF1465 PF07323.12 ORY54467.1 - 0.11 12.3 8.1 0.16 11.8 7.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1465) FUSC PF04632.12 ORY54467.1 - 0.57 8.6 5.2 0.58 8.6 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 ORY54467.1 - 0.98 7.9 3.4 1.2 7.6 3.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mei5_like PF17021.5 ORY54467.1 - 1.3 9.1 4.2 0.15 12.1 0.3 1.4 2 0 0 2 2 2 0 Putative double-strand recombination repair-like TMCO5 PF14992.6 ORY54467.1 - 2 7.9 8.2 2.9 7.4 8.2 1.2 1 0 0 1 1 1 0 TMCO5 family Fmp27_WPPW PF10359.9 ORY54467.1 - 2.3 7.0 8.8 2.9 6.7 8.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Glyco_hydro_cc PF11790.8 ORY54468.1 - 4.2e-60 203.3 1.8 5.5e-60 202.9 1.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Prominin PF05478.11 ORY54468.1 - 0.0072 14.4 0.0 0.0096 13.9 0.0 1.1 1 0 0 1 1 1 1 Prominin SpoIIIAH PF12685.7 ORY54468.1 - 0.012 15.4 4.4 0.012 15.4 4.4 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Glyco_hydro_2_C PF02836.17 ORY54468.1 - 0.1 11.7 0.4 0.28 10.2 0.4 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain XRCC4 PF06632.12 ORY54468.1 - 1.5 7.6 3.5 2.5 6.9 3.5 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 ThiF PF00899.21 ORY54469.1 - 1.6e-50 171.8 0.0 2.4e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 ORY54469.1 - 1.3e-08 35.4 0.0 3.3e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 ORY54469.1 - 0.0042 17.2 0.1 0.0072 16.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 ORY54469.1 - 0.0063 16.1 0.5 0.0096 15.5 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORY54469.1 - 0.019 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ORY54469.1 - 0.025 15.0 0.0 0.044 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 ORY54469.1 - 0.029 14.0 0.2 0.047 13.3 0.2 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 ORY54469.1 - 0.079 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Myb_DNA-binding PF00249.31 ORY54470.1 - 2.9e-07 30.6 0.3 9.5 6.5 0.0 5.4 5 0 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY54470.1 - 0.00014 22.0 1.4 4.5 7.6 0.0 4.5 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY54470.1 - 0.0036 17.6 1.3 0.44 11.0 0.2 3.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY54471.1 - 0.005 17.0 2.5 11 6.3 0.1 4.1 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY54471.1 - 0.22 11.9 4.9 0.68 10.4 0.1 3.5 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain GalP_UDP_transf PF01087.22 ORY54472.1 - 1.1e-64 218.2 0.0 1.7e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 ORY54472.1 - 9.2e-44 149.1 0.0 1.4e-42 145.3 0.0 2.5 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain TEA PF01285.18 ORY54473.1 - 9.5e-16 57.6 0.3 1.8e-15 56.8 0.3 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Myb_DNA-binding PF00249.31 ORY54474.1 - 7.7e-11 42.0 0.6 3e-06 27.3 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY54474.1 - 1.5e-08 34.7 1.0 0.0013 19.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORY54474.1 - 0.074 13.1 1.6 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain zf-C2H2 PF00096.26 ORY54476.1 - 1.8e-11 43.8 8.8 3.7e-05 24.0 2.7 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY54476.1 - 1.9e-06 28.2 8.5 0.012 16.4 0.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY54476.1 - 5.4e-06 26.6 10.3 5.1e-05 23.5 2.3 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-LYAR PF08790.11 ORY54476.1 - 0.014 15.3 3.9 0.08 12.9 1.1 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met PF12874.7 ORY54476.1 - 0.021 15.2 2.1 6.9 7.2 0.1 2.8 2 1 0 2 2 2 0 Zinc-finger of C2H2 type IBR PF01485.21 ORY54476.1 - 0.03 14.5 4.6 0.37 11.0 4.6 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf_C2H2_ZHX PF18387.1 ORY54476.1 - 0.03 13.9 1.1 0.098 12.3 0.2 1.9 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 ORY54476.1 - 0.042 14.1 4.3 0.91 9.9 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY54476.1 - 0.077 13.6 2.0 1.5 9.5 0.4 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain RhoGEF67_u1 PF16615.5 ORY54476.1 - 0.081 13.4 1.4 0.21 12.1 0.0 2.1 2 1 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 zf-TRAF PF02176.18 ORY54476.1 - 0.12 13.0 4.6 0.13 13.0 3.2 1.7 1 1 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORY54476.1 - 0.15 12.2 1.7 0.59 10.2 1.7 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORY54476.1 - 2.8 7.8 8.8 3.8 7.4 0.0 2.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Myb_DNA-bind_6 PF13921.6 ORY54477.1 - 8.2e-15 54.8 4.9 1.3e-07 31.8 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY54477.1 - 5.1e-13 49.0 16.6 3.4e-07 30.4 0.3 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY54477.1 - 0.00014 22.1 0.6 0.14 12.5 0.4 2.6 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like HTH_AsnC-type PF13404.6 ORY54477.1 - 0.031 14.1 0.0 0.088 12.7 0.0 1.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Myb_DNA-bind_5 PF13873.6 ORY54477.1 - 0.1 12.7 0.3 4.1 7.6 0.5 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain GalP_UDP_tr_C PF02744.17 ORY54478.1 - 5.1e-44 149.9 0.0 2.4e-43 147.7 0.0 2.0 2 1 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 ORY54478.1 - 4.1e-18 66.4 0.1 6.9e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain zf-TRAF PF02176.18 ORY54481.1 - 5.3e-05 23.8 16.4 9.9e-05 23.0 2.5 3.1 1 1 2 3 3 3 1 TRAF-type zinc finger Sina PF03145.16 ORY54481.1 - 0.0011 18.9 1.8 0.0011 18.9 1.8 3.0 1 1 2 3 3 3 1 Seven in absentia protein family Rootletin PF15035.6 ORY54481.1 - 0.012 15.6 0.6 0.018 15.0 0.6 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 ORY54481.1 - 0.018 14.9 0.8 0.027 14.3 0.8 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 ORY54481.1 - 0.036 14.5 0.8 0.065 13.7 0.8 1.3 1 0 0 1 1 1 0 Cell division protein ZapB HALZ PF02183.18 ORY54481.1 - 0.045 14.0 2.4 0.089 13.0 2.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 ORY54481.1 - 0.074 12.8 1.8 0.13 12.0 1.8 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 ORY54481.1 - 0.16 12.1 2.3 0.3 11.2 2.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor ADIP PF11559.8 ORY54481.1 - 0.47 10.5 2.7 0.64 10.1 2.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cupin_8 PF13621.6 ORY54482.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain MerC PF03203.14 ORY54483.1 - 0.012 16.1 6.3 0.012 16.1 6.3 2.4 2 1 0 2 2 2 0 MerC mercury resistance protein Astro_capsid_N PF03115.14 ORY54483.1 - 0.24 10.0 0.1 0.34 9.5 0.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor ASC PF00858.24 ORY54483.1 - 0.32 9.9 0.4 0.53 9.2 0.4 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Aminotran_1_2 PF00155.21 ORY54484.1 - 2.9e-42 145.2 0.0 3.2e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY54484.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORY54484.1 - 0.00016 20.7 0.0 0.013 14.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY54484.1 - 0.00018 20.1 0.0 0.00026 19.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Use1 PF09753.9 ORY54486.1 - 0.00037 20.3 0.0 0.00045 20.0 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF4457 PF14652.6 ORY54486.1 - 0.019 14.2 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) SNARE PF05739.19 ORY54486.1 - 0.03 14.3 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 SNARE domain Sec20 PF03908.13 ORY54486.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 1 1 2 2 2 0 Sec20 Nup88 PF10168.9 ORY54488.1 - 1.5e-27 95.8 0.0 1.1e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Nuclear pore component Nup54 PF13874.6 ORY54488.1 - 0.011 15.9 0.7 0.022 14.9 0.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 RhoGAP PF00620.27 ORY54588.1 - 2.9e-26 92.1 0.0 3.8e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Putative_PNPOx PF01243.20 ORY54590.1 - 1.8e-08 34.5 0.0 0.0007 19.7 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 ORY54590.1 - 8.2e-06 26.4 0.0 2.6e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY54590.1 - 0.0014 18.8 0.0 0.019 15.1 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 ORY54590.1 - 0.1 13.0 0.0 1.4 9.4 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain ATG16 PF08614.11 ORY54592.1 - 8.5e-47 160.0 27.3 9.4e-47 159.8 27.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 ORY54592.1 - 0.00091 18.8 17.3 0.0011 18.5 17.3 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Ycf1 PF05758.12 ORY54592.1 - 0.07 11.0 2.3 0.15 9.9 0.2 1.8 1 1 1 2 2 2 0 Ycf1 YabA PF06156.13 ORY54592.1 - 0.52 11.0 14.9 1.6 9.4 3.4 3.3 1 1 2 3 3 3 0 Initiation control protein YabA DUF2721 PF11026.8 ORY54592.1 - 1.5 8.7 7.2 0.42 10.5 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CCDC92 PF14916.6 ORY54592.1 - 1.8 8.4 8.4 2.2 8.1 2.0 3.1 2 1 1 3 3 3 0 Coiled-coil domain of unknown function DUF3138 PF11336.8 ORY54592.1 - 2 6.9 5.9 2.8 6.5 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CENP-H PF05837.12 ORY54592.1 - 8.4 6.8 24.1 2.3 8.6 2.7 3.1 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 ORY54592.1 - 8.8 6.5 11.1 2.3 8.4 7.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DOT1 PF08123.13 ORY54593.1 - 1.8e-58 197.5 0.0 2.3e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 4F5 PF04419.14 ORY54594.1 - 1.4e-07 32.2 11.3 1.4e-07 32.2 11.3 2.8 2 1 0 2 2 2 1 4F5 protein family F-box-like PF12937.7 ORY54596.1 - 7.4e-05 22.6 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY54596.1 - 0.0005 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain Porphobil_deam PF01379.20 ORY54597.1 - 4e-74 248.5 0.0 5.2e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ORY54597.1 - 6e-15 55.4 0.4 1.4e-13 51.0 0.4 2.6 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain NADH_B2 PF14813.6 ORY54598.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 IKI3 PF04762.12 ORY54599.1 - 1.4e-260 867.3 0.0 1.6e-260 867.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 ORY54599.1 - 2.1e-05 24.8 0.1 0.44 10.9 0.2 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CUE PF02845.16 ORY54599.1 - 0.19 11.5 0.2 6.1 6.6 0.0 2.6 2 0 0 2 2 2 0 CUE domain TauD PF02668.16 ORY54600.1 - 2.3e-43 148.9 0.2 2.9e-43 148.6 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA PF00004.29 ORY54601.1 - 5e-09 36.7 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY54601.1 - 1.3e-08 35.2 0.0 2.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY54601.1 - 1e-06 29.2 0.1 3.6e-05 24.2 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 ORY54601.1 - 0.0047 16.2 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 ORY54601.1 - 0.013 15.4 0.1 0.096 12.6 0.1 2.2 1 1 0 1 1 1 0 NACHT domain Cdc6_C PF09079.11 ORY54601.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 ORY54601.1 - 0.13 12.4 0.2 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA lid domain RNA_helicase PF00910.22 ORY54601.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.32 ORY54604.1 - 5.3e-29 99.9 15.4 3.1e-05 24.6 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY54604.1 - 1e-14 54.6 2.0 0.00018 21.7 0.2 6.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY54604.1 - 2.9e-07 29.8 0.2 0.0037 16.3 0.0 3.2 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PhyH PF05721.13 ORY54745.1 - 5.5e-10 39.8 0.0 7.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ORY54745.1 - 3.2e-07 29.4 0.1 4.9e-05 22.3 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ORY54745.1 - 0.0017 18.8 0.0 0.003 17.9 0.0 1.5 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase PH PF00169.29 ORY54746.1 - 9.1e-05 22.9 0.0 0.00018 22.0 0.0 1.5 1 0 0 1 1 1 1 PH domain Syntaxin-6_N PF09177.11 ORY54746.1 - 0.11 13.0 2.0 1.1 9.9 0.3 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Sporozoite_P67 PF05642.11 ORY54746.1 - 0.26 9.3 6.9 0.41 8.7 6.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SelP_N PF04592.14 ORY54746.1 - 2.9 7.2 11.6 5.4 6.4 11.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Cation_efflux PF01545.21 ORY54747.1 - 1.2e-45 155.7 0.3 1.9e-45 155.1 0.3 1.3 1 1 0 1 1 1 1 Cation efflux family GRP PF07172.11 ORY54747.1 - 0.0033 18.1 4.9 0.0033 18.1 4.9 2.6 2 0 0 2 2 2 2 Glycine rich protein family DUF2157 PF09925.9 ORY54747.1 - 0.25 11.1 5.3 2.2 8.1 0.5 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) TFIIE-A_C PF11521.8 ORY54747.1 - 1.5 9.1 5.5 11 6.4 0.5 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha HMG_box PF00505.19 ORY54748.1 - 1.7e-16 60.4 3.0 3.1e-16 59.6 3.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY54748.1 - 0.0003 21.3 2.7 0.00054 20.5 2.7 1.4 1 0 0 1 1 1 1 HMG-box domain UCH PF00443.29 ORY54749.1 - 3.7e-49 167.5 0.0 4.7e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY54749.1 - 2.8e-20 73.2 0.0 1.6e-19 70.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY54749.1 - 2.8e-09 37.2 13.1 2.8e-09 37.2 13.1 2.3 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein HalOD2 PF18547.1 ORY54749.1 - 0.06 13.3 3.5 3.2 7.7 0.1 3.5 3 0 0 3 3 3 0 Halobacterial output domain 2 Glyco_transf_20 PF00982.21 ORY54750.1 - 3.1e-184 613.1 0.0 2e-139 465.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 ORY54750.1 - 0.047 13.2 0.1 1.9 8.0 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 Clat_adaptor_s PF01217.20 ORY54751.1 - 2.6e-57 192.7 1.8 3.1e-57 192.5 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TRAM_LAG1_CLN8 PF03798.16 ORY54752.1 - 1e-34 120.0 22.8 1.9e-34 119.1 22.8 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 ORY54752.1 - 7.7e-21 73.5 0.0 1.8e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein COPIIcoated_ERV PF07970.12 ORY54753.1 - 1.2e-36 126.7 0.1 1.8e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY54753.1 - 1.1e-23 83.4 0.0 2.2e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Alg6_Alg8 PF03155.15 ORY54757.1 - 1.9e-116 389.9 14.2 5.5e-115 385.1 14.2 2.5 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Mito_carr PF00153.27 ORY54758.1 - 3.6e-75 248.0 1.5 3.7e-25 87.7 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 ORY54758.1 - 0.23 11.8 1.8 0.82 10.1 1.8 1.9 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family CENP-K PF11802.8 ORY54858.1 - 2.9e-12 46.7 0.0 1.7e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Centromere-associated protein K DUF4484 PF14831.6 ORY54858.1 - 0.22 11.6 2.4 0.27 11.3 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Raffinose_syn PF05691.12 ORY54859.1 - 2.2e-11 42.3 0.0 2.8e-10 38.7 0.0 2.4 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Abhydrolase_1 PF00561.20 ORY54860.1 - 0.00034 20.3 0.1 0.0022 17.7 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 ORY54861.1 - 3.7e-07 29.3 0.3 1.3e-06 27.5 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain UDPGP PF01704.18 ORY54862.1 - 2.8e-200 665.2 0.2 3.3e-200 665.0 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Cid2 PF09774.9 ORY54863.1 - 4.4e-25 89.0 0.3 5e-23 82.3 0.3 2.0 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Metallophos PF00149.28 ORY54864.1 - 3.5e-09 37.5 0.1 7.6e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3873 PF12989.7 ORY54866.1 - 0.022 15.1 0.1 0.045 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) G-gamma PF00631.22 ORY54866.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 GGL domain TPR_1 PF00515.28 ORY54867.1 - 8.5e-07 28.5 6.8 0.027 14.3 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY54867.1 - 7.3e-06 25.7 16.4 0.031 14.4 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY54867.1 - 0.024 14.6 4.3 0.36 11.0 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY54867.1 - 0.029 14.6 15.2 0.17 12.2 5.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY54867.1 - 0.29 12.0 9.7 4.8 8.3 1.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY54867.1 - 0.37 10.5 5.1 2.6 7.8 0.2 3.6 3 0 0 3 3 3 0 TPR repeat MIT PF04212.18 ORY54867.1 - 0.47 10.6 3.8 2.2 8.4 0.2 3.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain KCH PF16944.5 ORY54868.1 - 5.8e-90 301.5 13.9 7.5e-90 301.1 13.9 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3629 PF12302.8 ORY54868.1 - 0.079 12.4 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) MaAIMP_sms PF16951.5 ORY54868.1 - 1.6 8.6 4.9 3.6 7.4 4.9 1.6 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit Fungal_trans_2 PF11951.8 ORY54869.1 - 3e-09 36.2 0.0 2.1e-07 30.1 0.0 2.6 2 1 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY54869.1 - 0.046 13.9 5.1 0.087 13.0 5.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF357 PF04010.13 ORY54869.1 - 0.29 11.2 0.8 0.91 9.6 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF357) Aldo_ket_red PF00248.21 ORY54870.1 - 9.9e-50 169.4 0.0 8.3e-48 163.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 ORY54872.1 - 3.9e-22 78.4 0.2 5.4e-22 77.9 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 ORY54872.1 - 0.11 12.3 1.8 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit GFA PF04828.14 ORY54873.1 - 1.2e-21 76.8 0.7 1.8e-21 76.3 0.7 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Amidohydro_3 PF07969.11 ORY54874.1 - 1.3e-07 31.4 0.5 0.00049 19.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ORY54874.1 - 1.7e-06 27.6 0.0 6.6e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Amidohydrolase family Myb_DNA-bind_4 PF13837.6 ORY54875.1 - 0.00024 21.4 0.0 0.00039 20.7 0.0 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY54875.1 - 0.00031 20.9 0.0 0.00054 20.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY54875.1 - 0.00056 20.0 0.0 0.00087 19.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF508 PF04370.12 ORY54877.1 - 0.78 9.5 6.7 1.1 8.9 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) MPP6 PF10175.9 ORY54879.1 - 0.047 14.2 2.0 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Myb_DNA-bind_6 PF13921.6 ORY54881.1 - 7.1e-05 23.0 0.1 0.00011 22.4 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY54881.1 - 0.00021 21.4 0.5 0.00041 20.5 0.3 1.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain TALPID3 PF15324.6 ORY54881.1 - 0.13 9.9 4.4 0.16 9.6 4.4 1.0 1 0 0 1 1 1 0 Hedgehog signalling target AF-4 PF05110.13 ORY54881.1 - 0.31 9.1 14.1 0.33 9.0 14.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 ORY54881.1 - 2.5 6.6 4.5 2.5 6.6 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 ORY54881.1 - 9 5.0 6.9 10 4.9 6.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Fungal_trans PF04082.18 ORY54882.1 - 2.3e-22 79.3 0.2 3.3e-22 78.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY54882.1 - 4.3e-07 29.9 14.4 7.4e-07 29.2 14.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Iso_dh PF00180.20 ORY54883.1 - 7.4e-89 298.3 0.0 8.5e-89 298.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PTS_EIIC_2 PF13303.6 ORY54883.1 - 0.044 12.8 0.1 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC MFS_1 PF07690.16 ORY54884.1 - 4.5e-41 141.0 36.2 8.3e-40 136.8 24.2 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily HupE_UreJ PF04955.12 ORY54884.1 - 0.039 13.4 0.4 0.12 11.9 0.4 1.8 1 0 0 1 1 1 0 HupE / UreJ protein Cohesin_HEAT PF12765.7 ORY54884.1 - 0.073 13.4 0.0 0.65 10.3 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF4083 PF13314.6 ORY54884.1 - 0.078 12.9 0.1 17 5.4 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) His_Phos_2 PF00328.22 ORY54885.1 - 2.5e-33 116.0 0.0 3.1e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA_16 PF13191.6 ORY54886.1 - 0.0058 17.0 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 ORY54886.1 - 0.19 10.9 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Gp_dh_C PF02800.20 ORY54887.1 - 1.1e-50 171.3 0.0 1.3e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain MFS_1 PF07690.16 ORY54988.1 - 2.1e-26 92.7 38.2 2.1e-26 92.7 38.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY54988.1 - 2.6e-05 23.3 18.0 2.6e-05 23.3 18.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TctB PF07331.11 ORY54989.1 - 0.15 12.3 8.8 24 5.2 12.2 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family MARVEL PF01284.23 ORY54989.1 - 0.33 11.0 21.4 6.6 6.8 20.8 2.5 1 1 1 2 2 2 0 Membrane-associating domain Syndecan PF01034.20 ORY54990.1 - 0.18 11.7 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain GREB1 PF15782.5 ORY54990.1 - 1 6.4 7.0 1.4 5.9 7.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TrbI PF03743.14 ORY54990.1 - 8.8 6.1 11.2 0.19 11.6 2.1 2.4 2 1 1 3 3 3 0 Bacterial conjugation TrbI-like protein Fungal_trans PF04082.18 ORY54991.1 - 5.4e-06 25.6 0.0 7.1e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M20 PF01546.28 ORY54992.1 - 1.1e-10 41.5 0.1 1.7e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY54992.1 - 1.6e-08 34.4 0.1 5.7e-08 32.7 0.1 2.0 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 ORY54993.1 - 5.5e-37 127.5 32.6 5.5e-37 127.5 32.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY54993.1 - 2e-06 27.4 28.1 8.9e-05 21.9 28.1 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Phage_holin_2_4 PF16082.5 ORY54993.1 - 0.26 11.0 6.0 6.3 6.6 0.0 3.8 3 1 0 3 3 3 0 Bacteriophage holin family, superfamily II-like DUF4956 PF16316.5 ORY54993.1 - 4 7.1 8.5 22 4.7 8.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4956) MotA_ExbB PF01618.16 ORY54993.1 - 5.9 6.7 6.3 0.6 9.9 0.7 2.1 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Peptidase_M20 PF01546.28 ORY54994.1 - 5.4e-09 36.0 0.2 8.3e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY54994.1 - 2.9e-08 33.6 0.1 7.6e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 ORY54995.1 - 1.7e-32 112.8 33.3 1.7e-32 112.8 33.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY54995.1 - 5.5e-08 32.5 7.5 5.5e-08 32.5 7.5 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TPR_2 PF07719.17 ORY54996.1 - 5.4e-20 69.8 19.9 0.009 16.1 0.0 11.8 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY54996.1 - 4.7e-17 60.7 8.1 0.0023 18.0 0.0 10.8 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY54996.1 - 1.2e-13 50.3 11.9 0.53 10.2 0.0 9.4 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY54996.1 - 1e-12 48.4 16.3 0.00041 20.8 1.4 7.8 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY54996.1 - 4e-12 46.6 20.3 0.19 12.4 0.1 7.7 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 ORY54996.1 - 5.7e-12 45.5 5.6 0.058 14.0 0.0 8.9 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY54996.1 - 9.2e-11 41.6 26.7 0.12 13.2 0.1 11.1 8 3 4 12 12 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY54996.1 - 1.1e-07 31.5 0.1 0.25 11.1 0.0 5.3 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 ORY54996.1 - 1.7e-06 28.0 8.6 1.1 9.7 0.0 7.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY54996.1 - 5.8e-05 22.8 13.5 1 9.5 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat PknG_TPR PF16918.5 ORY54996.1 - 0.00042 19.2 0.8 0.22 10.2 0.1 3.7 4 0 0 4 4 4 1 Protein kinase G tetratricopeptide repeat ChAPs PF09295.10 ORY54996.1 - 0.00066 18.8 0.0 0.62 9.0 0.1 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 ORY54996.1 - 0.0029 17.9 12.9 0.34 11.3 2.8 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY54996.1 - 0.0051 17.1 33.1 0.26 11.6 0.9 10.3 9 4 2 12 12 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY54996.1 - 0.01 16.1 8.4 0.016 15.4 1.6 4.3 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 ORY54996.1 - 0.011 16.1 0.0 2.9 8.3 0.1 2.9 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_9 PF13371.6 ORY54996.1 - 0.029 14.5 10.9 3.5 7.8 0.0 6.1 6 1 0 6 6 5 0 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY54996.1 - 0.037 14.3 0.0 3.8 7.8 0.1 3.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 ANAPC5 PF12862.7 ORY54996.1 - 0.2 11.8 1.1 32 4.7 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.12 ORY54996.1 - 0.29 11.2 1.6 6.2 6.9 0.1 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY54996.1 - 0.49 11.2 14.9 43 5.2 1.5 5.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_pol_phi PF04931.13 ORY54996.1 - 0.55 8.3 11.9 0.84 7.7 11.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 ORY54996.1 - 0.85 7.7 7.8 1.6 6.8 7.8 1.4 1 0 0 1 1 1 0 Nop14-like family Sel1 PF08238.12 ORY54996.1 - 3.2 8.6 5.6 8.4 7.2 0.3 4.0 3 1 0 3 3 3 0 Sel1 repeat BNIP2 PF12496.8 ORY54996.1 - 6.3 7.2 10.8 2.5 8.5 7.4 2.1 2 0 0 2 2 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 MFS_1 PF07690.16 ORY54997.1 - 8.7e-16 57.8 39.6 2.3e-14 53.1 23.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SGT1 PF07093.11 ORY54998.1 - 2.5e-86 290.4 0.0 1.2e-85 288.2 0.0 2.0 2 0 0 2 2 2 1 SGT1 protein Glyco_transf_28 PF03033.20 ORY54999.1 - 6e-27 94.4 0.0 1.1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 ORY54999.1 - 4.8e-19 68.3 0.1 7.7e-10 38.7 0.0 3.5 3 0 0 3 3 3 3 GRAM domain UDPGT PF00201.18 ORY54999.1 - 2.6e-07 29.8 0.0 1.8e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 ORY54999.1 - 4.9e-07 30.2 0.1 4.3e-06 27.2 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 ORY54999.1 - 4.5e-05 23.7 0.0 0.00078 19.7 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_tran_28_C PF04101.16 ORY54999.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CAP_N PF01213.19 ORY55000.1 - 0.29 10.6 5.0 0.35 10.3 5.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Xpo1 PF08389.12 ORY55001.1 - 6.3e-15 55.5 0.0 4.1e-14 52.9 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 ORY55001.1 - 1.3e-05 25.0 0.0 3.8e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 ORY55001.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat UME PF08064.13 ORY55001.1 - 0.21 11.5 0.5 2.7 8.0 0.0 3.1 4 0 0 4 4 4 0 UME (NUC010) domain HEAT_2 PF13646.6 ORY55002.1 - 3.8e-27 94.5 1.0 9e-13 48.4 0.1 3.4 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 ORY55002.1 - 2.2e-23 80.5 0.0 0.0015 19.0 0.0 6.9 8 0 0 8 8 8 6 PBS lyase HEAT-like repeat HEAT PF02985.22 ORY55002.1 - 5.5e-10 38.6 0.2 0.016 15.4 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 ORY55002.1 - 0.00017 22.0 0.2 6.9 7.3 0.0 4.1 2 2 2 4 4 4 3 HEAT-like repeat Arm PF00514.23 ORY55002.1 - 0.00093 19.2 0.0 0.89 9.7 0.0 3.3 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat Ribosomal_L10 PF00466.20 ORY55003.1 - 4.2e-22 78.2 0.0 6.3e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORY55003.1 - 7.1e-22 77.2 0.0 1.2e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Sina PF03145.16 ORY55004.1 - 3.6e-08 33.6 5.9 0.0025 17.8 1.9 2.3 1 1 1 2 2 2 2 Seven in absentia protein family zf-C3HC4_3 PF13920.6 ORY55004.1 - 9.5e-07 28.6 3.7 9.5e-07 28.6 3.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY55004.1 - 1.4e-06 28.0 6.9 1.4e-06 28.0 6.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY55004.1 - 3.8e-06 26.6 6.1 3.8e-06 26.6 6.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY55004.1 - 4.3e-06 27.0 6.8 4.3e-06 27.0 6.8 2.8 3 0 0 3 3 3 1 Ring finger domain zf-TRAF PF02176.18 ORY55004.1 - 1.1e-05 26.0 0.8 1.1e-05 26.0 0.8 4.2 2 2 3 5 5 5 1 TRAF-type zinc finger Prok-RING_4 PF14447.6 ORY55004.1 - 1.1e-05 25.1 5.4 4.1e-05 23.4 5.4 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY55004.1 - 0.00036 20.5 4.8 0.0018 18.3 2.8 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY55004.1 - 0.00094 19.1 8.4 0.0011 18.9 6.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 ORY55004.1 - 0.026 14.3 5.5 0.026 14.3 5.5 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 ORY55004.1 - 0.029 14.3 4.0 0.029 14.3 4.0 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein U-box PF04564.15 ORY55004.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-C3HC4_4 PF15227.6 ORY55004.1 - 0.49 10.6 9.8 0.34 11.1 7.4 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_14 PF17978.1 ORY55004.1 - 1.6 9.2 6.1 0.15 12.5 1.0 2.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 ORY55004.1 - 4.4 7.7 18.0 0.085 13.2 7.2 3.2 2 2 0 2 2 2 0 RING-H2 zinc finger domain CSN8_PSD8_EIF3K PF10075.9 ORY55005.1 - 9.6e-16 58.1 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 ORY55005.1 - 0.0023 17.3 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family Proteasome PF00227.26 ORY55006.1 - 1.3e-34 119.3 0.3 1.7e-29 102.7 0.2 2.0 1 1 1 2 2 2 2 Proteasome subunit MDMPI_N PF11716.8 ORY55007.1 - 0.0029 18.3 0.4 0.0055 17.4 0.1 1.5 1 1 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain DinB PF05163.12 ORY55007.1 - 0.02 14.8 0.2 0.042 13.8 0.2 1.6 1 1 0 1 1 1 0 DinB family zf-RING_UBOX PF13445.6 ORY55009.1 - 0.0026 17.7 11.2 0.039 14.0 6.1 2.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-TRAF PF02176.18 ORY55009.1 - 0.0032 18.1 1.6 0.0032 18.1 1.6 3.3 3 1 1 4 4 2 2 TRAF-type zinc finger zf-C3HC4 PF00097.25 ORY55009.1 - 0.0038 17.1 13.5 0.014 15.3 13.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY55009.1 - 0.006 16.4 12.1 0.032 14.1 12.1 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORY55009.1 - 0.011 15.6 3.5 0.034 14.0 3.5 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Jnk-SapK_ap_N PF09744.9 ORY55009.1 - 0.049 13.9 0.9 0.069 13.4 0.9 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cep57_MT_bd PF06657.13 ORY55009.1 - 0.056 13.9 3.2 0.1 13.1 3.2 1.4 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Sina PF03145.16 ORY55009.1 - 0.068 13.1 11.1 0.19 11.7 1.0 3.2 1 1 1 3 3 3 0 Seven in absentia protein family PKcGMP_CC PF16808.5 ORY55009.1 - 0.16 11.8 9.1 0.54 10.2 9.2 1.8 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-RING_5 PF14634.6 ORY55009.1 - 0.68 9.9 13.3 1.9 8.5 11.5 2.8 2 1 0 2 2 2 0 zinc-RING finger domain XhlA PF10779.9 ORY55009.1 - 1.4 9.1 2.8 19 5.6 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA zf-C3HC4_4 PF15227.6 ORY55009.1 - 1.6 8.9 16.4 0.53 10.5 12.5 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY55009.1 - 3.3 7.6 18.2 0.054 13.4 10.3 2.2 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_9 PF16293.5 ORY55009.1 - 5 7.0 6.6 13 5.7 0.2 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Zn-C2H2_12 PF18112.1 ORY55009.1 - 6.7 7.3 7.6 8.6 6.9 0.8 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain NB-ARC PF00931.22 ORY55010.1 - 7.4e-08 31.9 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 ORY55010.1 - 4.9e-05 23.3 0.0 0.00015 21.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY55010.1 - 0.01 16.1 0.0 0.039 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY55010.1 - 0.014 15.8 0.4 0.014 15.8 0.4 3.5 4 1 0 4 4 4 0 AAA ATPase domain AAA_25 PF13481.6 ORY55010.1 - 0.034 13.7 0.2 0.35 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain TGS PF02824.21 ORY55010.1 - 0.087 12.9 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 TGS domain RsgA_GTPase PF03193.16 ORY55010.1 - 0.099 12.5 0.1 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase adh_short PF00106.25 ORY55011.1 - 3.4e-22 78.8 0.0 7.1e-22 77.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY55011.1 - 9.2e-15 54.8 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY55011.1 - 1.9e-07 31.2 0.0 2.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY55011.1 - 0.041 13.3 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY55011.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Prenylcys_lyase PF07156.14 ORY55012.1 - 8.5e-57 192.9 0.0 1.2e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 ORY55012.1 - 2.1e-09 37.5 0.0 4.7e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY55012.1 - 2e-06 27.7 0.1 3.2e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY55012.1 - 0.0022 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY55012.1 - 0.019 15.5 0.3 0.04 14.5 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY55012.1 - 0.03 13.4 0.5 0.044 12.9 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 ORY55012.1 - 0.069 12.4 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 ORY55012.1 - 0.11 11.6 1.2 0.17 11.0 1.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Dicer_N PF17895.1 ORY55012.1 - 0.12 12.2 1.1 3.8 7.3 0.0 3.0 2 1 0 2 2 2 0 Giardia Dicer N-terminal domain Peptidase_C48 PF02902.19 ORY55013.1 - 2.7e-33 115.6 0.1 3.2e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 ORY55013.1 - 0.024 13.4 0.0 3.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase Peptidase_C5 PF00770.18 ORY55013.1 - 0.031 14.0 0.1 0.098 12.3 0.1 1.8 1 1 1 2 2 2 0 Adenovirus endoprotease G-patch_2 PF12656.7 ORY55144.1 - 1.7e-23 82.4 0.5 5.5e-23 80.8 0.5 2.0 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 ORY55144.1 - 0.012 15.5 2.6 0.042 13.7 2.6 2.0 1 1 0 1 1 1 0 G-patch domain eIF-5_eIF-2B PF01873.17 ORY55145.1 - 7.5e-39 132.2 0.0 1.6e-38 131.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 ORY55145.1 - 6.2e-24 84.0 1.3 2.6e-23 81.9 0.0 2.7 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon BLOC1S3 PF15753.5 ORY55145.1 - 0.002 18.3 1.4 0.0049 17.0 1.4 1.6 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 SPT2 PF08243.11 ORY55145.1 - 0.31 11.6 6.9 0.47 11.0 5.8 1.9 1 1 0 1 1 1 0 SPT2 chromatin protein EPL1 PF10513.9 ORY55146.1 - 7.2e-22 78.5 0.1 1.7e-21 77.2 0.0 1.7 2 0 0 2 2 2 1 Enhancer of polycomb-like TRAM_LAG1_CLN8 PF03798.16 ORY55147.1 - 1.2e-32 113.2 19.3 1.2e-32 113.2 19.3 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORY55147.1 - 9.8e-17 60.4 0.0 2.3e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein LSM14 PF12701.7 ORY55148.1 - 4.4e-29 100.4 0.0 7e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 ORY55148.1 - 3.4e-08 33.5 0.0 7.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain TFIIA PF03153.13 ORY55148.1 - 0.12 12.4 25.6 0.57 10.1 10.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FDF PF09532.10 ORY55148.1 - 0.42 11.5 22.3 0.09 13.7 2.4 3.7 3 1 1 4 4 4 0 FDF domain GET2 PF08690.10 ORY55148.1 - 8.2 6.0 10.9 1.3 8.6 1.9 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 MFS_1 PF07690.16 ORY55150.1 - 4.2e-14 52.3 41.8 4.4e-13 48.9 29.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORY55150.1 - 1.7e-09 37.5 2.6 1.7e-09 37.5 2.6 2.4 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 RTX PF02382.15 ORY55150.1 - 0.3 10.7 1.1 0.46 10.1 1.1 1.2 1 0 0 1 1 1 0 N-terminal domain in RTX protein Aminotran_5 PF00266.19 ORY55151.1 - 1.5e-89 300.6 0.0 1.7e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY55151.1 - 6.6e-05 22.3 0.0 8.6e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY55151.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.18 ORY55152.1 - 3e-05 24.0 10.4 6.1e-05 23.0 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY55152.1 - 0.00033 19.8 0.0 0.0006 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 ORY55152.1 - 2.6 8.2 6.5 23 5.2 3.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor Tubulin PF00091.25 ORY55153.1 - 3e-70 236.5 0.0 1e-69 234.7 0.0 1.8 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY55153.1 - 2.6e-46 156.9 0.4 2.6e-46 156.9 0.4 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY55153.1 - 3.3e-05 24.2 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY55153.1 - 0.0039 16.9 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain HEAT PF02985.22 ORY55154.1 - 9.3e-13 47.3 2.7 0.053 13.8 0.0 7.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 ORY55154.1 - 1.8e-05 25.0 12.0 0.00072 19.9 0.7 5.8 5 2 1 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 ORY55154.1 - 0.045 14.3 2.8 0.72 10.4 0.6 3.9 3 1 1 4 4 4 0 HEAT-like repeat CDC27 PF09507.10 ORY55154.1 - 1.3 8.3 11.3 2.7 7.3 11.3 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CBM_26 PF16824.5 ORY55155.1 - 0.088 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 C-terminal carbohydrate-binding module Proteasome PF00227.26 ORY55157.1 - 1.1e-59 201.2 0.0 1.9e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY55157.1 - 1.8e-11 43.5 0.1 3.4e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NuDC PF16273.5 ORY55157.1 - 0.013 16.0 0.3 0.022 15.3 0.3 1.3 1 0 0 1 1 1 0 Nuclear distribution C domain FtsZ_C PF12327.8 ORY55157.1 - 0.029 14.6 0.5 0.067 13.5 0.5 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain DEAD PF00270.29 ORY55158.1 - 4.6e-47 160.1 0.0 6.4e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY55158.1 - 5.7e-30 103.9 0.0 3e-29 101.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY55158.1 - 3.3e-05 24.0 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_25 PF13649.6 ORY55159.1 - 4.6e-13 49.7 0.0 8.1e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY55159.1 - 1.6e-10 41.5 0.0 2.9e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY55159.1 - 7e-10 38.9 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY55159.1 - 1.4e-07 31.5 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY55159.1 - 5.3e-05 23.9 0.0 0.00013 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY55159.1 - 0.00013 21.4 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 ORY55159.1 - 0.0021 16.7 0.0 0.0034 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 ORY55159.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 ORY55159.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Hypothetical methyltransferase MFS_1 PF07690.16 ORY55160.1 - 2.3e-29 102.5 41.9 3.1e-29 102.0 41.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3421 PF11901.8 ORY55161.1 - 4.1e-31 107.4 2.1 6.5e-28 97.0 0.3 1.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) Peptidase_C78 PF07910.13 ORY55163.1 - 3e-42 144.5 0.0 5.4e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C78 SR-25 PF10500.9 ORY55164.1 - 2.8 7.5 8.8 4 7.0 8.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 ORY55165.1 - 6.8e-14 52.0 6.1 7.5e-06 26.6 0.0 6.0 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY55165.1 - 0.00012 22.4 0.0 1.1 9.7 0.0 4.4 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORY55165.1 - 0.015 15.7 1.2 34 5.1 0.1 4.0 3 0 0 3 3 3 0 PQQ-like domain Reg_prop PF07494.11 ORY55165.1 - 0.21 11.9 0.3 1 9.8 0.1 2.4 3 0 0 3 3 3 0 Two component regulator propeller SKN1 PF03935.15 ORY55166.1 - 1.7e-168 561.1 2.8 2.2e-168 560.8 2.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TPR_21 PF09976.9 ORY55166.1 - 0.33 10.6 0.4 0.52 10.0 0.4 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain zf-C3HC4_5 PF17121.5 ORY55167.1 - 1.2e-21 76.3 8.3 1.9e-21 75.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MAT1 PF06391.13 ORY55167.1 - 2e-19 70.2 0.4 2.4e-19 70.0 0.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.6 ORY55167.1 - 3.1e-06 27.0 8.7 5.6e-06 26.1 8.7 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY55167.1 - 7.3e-06 25.8 7.7 1.3e-05 24.9 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY55167.1 - 3.2e-05 23.7 8.9 5.7e-05 22.9 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY55167.1 - 3.2e-05 24.2 8.7 4.5e-05 23.7 8.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY55167.1 - 7.6e-05 22.6 9.2 0.00028 20.8 9.3 1.9 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY55167.1 - 0.00025 20.9 10.8 0.004 17.0 11.0 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY55167.1 - 0.0024 17.6 6.0 0.0073 16.1 1.9 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 ORY55167.1 - 0.0035 17.3 2.8 0.0035 17.3 2.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 ORY55167.1 - 0.024 14.5 0.8 0.024 14.5 0.8 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein DUF3797 PF12677.7 ORY55167.1 - 0.038 13.9 0.7 0.038 13.9 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) DNA_ligase_ZBD PF03119.16 ORY55167.1 - 0.041 13.9 2.3 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-UDP PF14569.6 ORY55167.1 - 0.2 11.8 7.3 1.2 9.3 7.3 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 ORY55167.1 - 0.23 11.6 7.3 0.33 11.1 7.2 1.5 1 1 0 1 1 1 0 zinc RING finger of MSL2 FYDLN_acid PF09538.10 ORY55167.1 - 0.24 12.1 1.8 0.2 12.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-piccolo PF05715.13 ORY55167.1 - 0.32 11.2 6.8 10 6.3 3.6 2.5 2 1 0 2 2 2 0 Piccolo Zn-finger Baculo_IE-1 PF05290.11 ORY55167.1 - 1.8 8.5 9.1 0.7 9.8 1.5 2.2 1 1 1 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.14 ORY55167.1 - 3 7.8 7.5 15 5.6 0.3 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-FPG_IleRS PF06827.14 ORY55167.1 - 3.2 7.7 9.5 0.85 9.5 0.4 2.7 3 0 0 3 3 2 0 Zinc finger found in FPG and IleRS Ammonium_transp PF00909.21 ORY55168.1 - 1.2e-81 274.4 22.6 1.9e-79 267.2 22.6 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family MFS_1 PF07690.16 ORY55169.1 - 8.7e-19 67.6 55.3 8.7e-19 67.6 55.3 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY55169.1 - 0.00074 18.9 24.1 0.0011 18.3 24.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 ORY55170.1 - 3.5e-14 52.5 55.6 3.5e-14 52.5 55.6 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily F-box-like PF12937.7 ORY55171.1 - 0.045 13.7 0.4 0.079 12.9 0.4 1.4 1 0 0 1 1 1 0 F-box-like V-ATPase_H_N PF03224.14 ORY55172.1 - 1.1e-82 277.9 0.2 1.1e-82 277.9 0.2 1.3 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORY55172.1 - 1.3e-40 138.2 0.1 2.2e-39 134.2 0.0 2.7 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 ORY55172.1 - 0.026 14.6 8.0 0.93 9.6 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Zn_clus PF00172.18 ORY55173.1 - 4.2e-05 23.6 9.9 6.9e-05 22.9 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AF-4 PF05110.13 ORY55173.1 - 2 6.4 8.6 2.8 5.9 8.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 ORY55173.1 - 3.6 7.1 13.2 6.8 6.2 13.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein F-box-like PF12937.7 ORY55174.1 - 1.4e-08 34.5 0.7 3.4e-08 33.2 0.7 1.7 1 0 0 1 1 1 1 F-box-like Mlh1_C PF16413.5 ORY55174.1 - 0.23 10.8 0.0 0.41 10.0 0.0 1.3 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus NAD_binding_8 PF13450.6 ORY55310.1 - 1.7e-10 41.0 0.0 6e-10 39.2 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ORY55310.1 - 5.9e-10 38.2 0.1 3.2e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY55310.1 - 3.9e-07 29.6 0.0 7.8e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY55310.1 - 3e-06 26.6 0.1 9.7e-05 21.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY55310.1 - 3.6e-06 26.4 0.0 1.2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY55310.1 - 0.00017 21.7 0.0 1.1 9.3 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 ORY55310.1 - 0.00023 20.9 0.2 0.0016 18.1 0.1 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY55310.1 - 0.00029 20.2 0.2 0.0011 18.4 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ORY55310.1 - 0.0011 19.0 0.0 0.0074 16.3 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY55310.1 - 0.025 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY55310.1 - 0.15 11.1 0.0 3.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 ORY55310.1 - 0.19 10.9 0.0 0.64 9.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Syja_N PF02383.18 ORY55311.1 - 5.9e-78 262.4 0.0 8.6e-78 261.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 ORY55311.1 - 1.2e-29 102.3 0.0 2.9e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase BCS1_N PF08740.11 ORY55311.1 - 0.0011 19.0 0.2 0.0022 18.0 0.2 1.4 1 0 0 1 1 1 1 BCS1 N terminal DUF4611 PF15387.6 ORY55311.1 - 1.4 9.2 4.4 3.8 7.8 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) TFIID-18kDa PF02269.16 ORY55312.1 - 1e-20 73.5 0.0 2.2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Presenilin PF01080.17 ORY55312.1 - 0.66 8.7 1.2 1.1 7.9 1.2 1.3 1 0 0 1 1 1 0 Presenilin DUF809 PF05663.11 ORY55312.1 - 5.5 7.1 6.7 12 6.1 6.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Cullin_binding PF03556.15 ORY55313.1 - 3.5e-24 85.5 0.0 5.9e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Cullin binding SAGA-Tad1 PF12767.7 ORY55313.1 - 0.98 9.1 4.9 1.2 8.8 4.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ndc1_Nup PF09531.10 ORY55313.1 - 2.1 7.0 8.7 2.6 6.6 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SWI-SNF_Ssr4 PF08549.10 ORY55313.1 - 9.7 4.7 13.8 12 4.3 13.8 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-C3HC4_2 PF13923.6 ORY55314.1 - 6.3e-11 41.9 6.3 6.3e-11 41.9 6.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORY55314.1 - 6.9e-09 35.5 1.5 1.2e-08 34.7 1.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.25 ORY55314.1 - 1e-06 28.5 7.6 1e-06 28.5 7.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY55314.1 - 1.2e-06 28.4 5.8 1.2e-06 28.4 5.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY55314.1 - 4.1e-06 26.7 7.4 4.1e-06 26.7 7.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY55314.1 - 0.00011 22.5 7.0 0.00011 22.5 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain U-box PF04564.15 ORY55314.1 - 0.00025 21.2 0.1 0.0011 19.2 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-C3HC4_3 PF13920.6 ORY55314.1 - 0.00027 20.7 4.4 0.00027 20.7 4.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORY55314.1 - 0.00043 20.4 2.0 0.00043 20.4 2.0 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 ORY55314.1 - 0.00071 19.3 4.7 0.0018 18.0 4.7 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ORY55314.1 - 0.00096 19.3 8.0 0.00096 19.3 8.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING SAP PF02037.27 ORY55314.1 - 0.008 15.9 0.1 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 SAP domain zf-rbx1 PF12678.7 ORY55314.1 - 0.026 14.8 5.8 0.026 14.8 5.8 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain TRAF6_Z2 PF18048.1 ORY55314.1 - 0.086 12.9 0.1 0.086 12.9 0.1 2.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 Prok-RING_4 PF14447.6 ORY55314.1 - 0.44 10.4 11.7 1 9.3 7.7 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 UBZ_FAAP20 PF15750.5 ORY55314.1 - 0.49 10.4 3.8 0.77 9.8 1.1 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-ANAPC11 PF12861.7 ORY55314.1 - 0.85 9.7 4.0 1.1 9.3 1.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MRPL52 PF18699.1 ORY55314.1 - 9.2 6.5 8.4 1.2 9.4 1.9 2.6 2 0 0 2 2 2 0 Mitoribosomal protein mL52 ADK PF00406.22 ORY55315.1 - 3.7e-59 199.2 0.1 5e-59 198.7 0.1 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY55315.1 - 1.3e-22 80.7 0.1 2.7e-22 79.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 ORY55315.1 - 4.1e-16 58.7 0.0 8.3e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 ORY55315.1 - 0.0018 18.8 0.0 0.0039 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY55315.1 - 0.012 15.7 0.0 0.035 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain LPP PF04728.13 ORY55315.1 - 0.023 15.1 3.2 0.063 13.7 3.2 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Rop-like PF05082.13 ORY55315.1 - 0.064 13.1 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 Rop-like Mg_chelatase PF01078.21 ORY55315.1 - 0.079 12.3 0.1 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.17 ORY55315.1 - 0.11 12.2 0.1 0.5 10.0 0.0 2.1 3 0 0 3 3 3 0 Thymidylate kinase DUF3810 PF12725.7 ORY55315.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) BssS PF13991.6 ORY55315.1 - 0.19 11.8 0.7 0.55 10.3 0.1 2.0 2 0 0 2 2 2 0 BssS protein family ABC_tran_CTD PF16326.5 ORY55315.1 - 0.21 11.9 2.3 0.3 11.4 0.2 2.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4795 PF16043.5 ORY55315.1 - 0.26 10.9 3.3 0.23 11.0 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Apolipoprotein PF01442.18 ORY55315.1 - 0.54 10.1 6.6 3.6 7.4 5.1 2.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 ORY55315.1 - 0.68 10.6 3.2 1.5 9.5 0.6 2.5 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 ORY55315.1 - 1.4 9.5 5.9 24 5.5 5.4 3.3 3 1 0 3 3 3 0 YtxH-like protein Ribosomal_S14 PF00253.21 ORY55317.1 - 6.3e-22 77.1 0.1 8.9e-22 76.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e MAPEG PF01124.18 ORY55318.1 - 3.6e-24 85.1 1.5 4.2e-24 84.9 1.5 1.1 1 0 0 1 1 1 1 MAPEG family Abhydrolase_3 PF07859.13 ORY55319.1 - 1.9e-23 83.5 0.0 1.2e-22 80.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY55319.1 - 2.4e-10 39.8 0.0 6.3e-10 38.5 0.0 1.6 2 1 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY55319.1 - 0.0023 16.9 0.1 0.0064 15.4 0.0 1.6 2 0 0 2 2 2 1 Carboxylesterase family WD40 PF00400.32 ORY55320.1 - 6.1e-27 93.3 17.8 1.8e-06 28.6 2.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PFU PF09070.11 ORY55320.1 - 3e-22 79.0 0.0 5.5e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Na_Ca_ex PF01699.24 ORY55321.1 - 1e-39 135.9 31.6 8.6e-21 74.5 17.1 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein MARVEL PF01284.23 ORY55322.1 - 1.5e-05 25.1 15.9 3e-05 24.1 15.9 1.5 1 1 0 1 1 1 1 Membrane-associating domain DAHP_synth_2 PF01474.16 ORY55323.1 - 9.5e-183 607.7 0.0 1.3e-181 603.9 0.0 1.9 1 1 0 1 1 1 1 Class-II DAHP synthetase family zf-C2H2_2 PF12756.7 ORY55324.1 - 2.6e-30 104.7 8.1 1.3e-15 57.5 0.2 4.2 4 0 0 4 4 4 4 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY55324.1 - 3.4e-05 24.0 16.7 7.9e-05 22.8 2.8 4.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY55324.1 - 0.0058 17.0 13.8 0.046 14.1 2.5 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 ORY55324.1 - 0.5 10.6 5.7 3.3 7.9 0.1 3.5 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DNA_pol_phi PF04931.13 ORY55324.1 - 3.1 5.8 8.8 4.7 5.2 8.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Glycophorin_A PF01102.18 ORY55325.1 - 0.0026 18.0 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 Glycophorin A Romo1 PF10247.9 ORY55325.1 - 0.0086 16.4 0.1 0.022 15.1 0.1 1.7 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Amnionless PF14828.6 ORY55325.1 - 0.01 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless Gly-zipper_Omp PF13488.6 ORY55325.1 - 0.02 14.9 4.7 0.067 13.2 4.7 2.0 1 0 0 1 1 1 0 Glycine zipper TMEM154 PF15102.6 ORY55325.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family SKG6 PF08693.10 ORY55325.1 - 0.024 14.0 0.8 0.055 12.9 0.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM51 PF15345.6 ORY55325.1 - 0.04 13.7 0.1 0.07 13.0 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 Rick_17kDa_Anti PF05433.15 ORY55325.1 - 0.047 13.5 6.4 0.16 11.8 6.4 2.0 1 0 0 1 1 1 0 Glycine zipper 2TM domain Mid2 PF04478.12 ORY55325.1 - 0.068 13.0 0.5 0.31 10.9 0.2 2.1 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor EphA2_TM PF14575.6 ORY55325.1 - 0.078 13.9 0.0 0.16 12.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gly-zipper_YMGG PF13441.6 ORY55325.1 - 0.2 11.5 5.1 0.61 9.9 5.1 1.8 1 0 0 1 1 1 0 YMGG-like Gly-zipper TrbL PF04610.14 ORY55325.1 - 1.5 8.6 3.9 1.1 8.9 2.0 1.7 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein tRNA-synt_1g PF09334.11 ORY55326.1 - 8.7e-87 291.4 0.0 1.7e-85 287.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY55326.1 - 5.7e-13 48.0 0.2 1.2e-08 33.7 0.0 2.8 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ORY55326.1 - 4.2e-06 26.3 0.0 0.0039 16.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 ORY55326.1 - 0.0078 16.2 0.0 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA CopB PF05275.11 ORY55326.1 - 0.11 12.0 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Copper resistance protein B precursor (CopB) Cep57_CLD PF14073.6 ORY55327.1 - 0.0028 17.7 0.7 0.0049 16.9 0.7 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 zf-CCCH PF00642.24 ORY55327.1 - 0.089 12.7 0.9 0.089 12.7 0.9 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 ORY55329.1 - 5.1e-08 32.8 5.8 1e-07 31.8 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain YabA PF06156.13 ORY55329.1 - 0.00055 20.5 0.1 0.00085 19.9 0.1 1.3 1 0 0 1 1 1 1 Initiation control protein YabA Shugoshin_N PF07558.11 ORY55329.1 - 0.0027 17.5 1.4 0.0045 16.8 1.4 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region NRBF2 PF08961.10 ORY55329.1 - 0.0033 17.0 0.2 0.0051 16.4 0.2 1.3 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Anti-TRAP PF15777.5 ORY55329.1 - 0.005 16.8 1.8 0.014 15.3 0.5 2.2 2 0 0 2 2 2 1 Tryptophan RNA-binding attenuator protein inhibitory protein bZIP_1 PF00170.21 ORY55329.1 - 0.0075 16.3 1.9 0.015 15.4 1.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 ORY55329.1 - 0.013 15.8 0.1 0.028 14.7 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.15 ORY55329.1 - 0.015 15.3 1.4 0.027 14.5 1.4 1.4 1 0 0 1 1 1 0 Basic region leucine zipper zf-C3HC4 PF00097.25 ORY55329.1 - 0.023 14.6 6.4 0.042 13.7 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DivIC PF04977.15 ORY55329.1 - 0.027 14.2 0.3 0.043 13.6 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 ORY55329.1 - 0.031 14.5 1.0 0.055 13.7 0.7 1.6 1 1 1 2 2 2 0 Homeobox associated leucine zipper zf-RING_UBOX PF13445.6 ORY55329.1 - 0.15 12.1 6.6 0.29 11.2 6.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger CtIP_N PF10482.9 ORY55329.1 - 0.55 10.3 3.5 0.15 12.2 0.5 1.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Prok-RING_4 PF14447.6 ORY55329.1 - 0.59 10.0 7.1 2.4 8.1 7.4 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY55329.1 - 1.6 9.1 6.4 3 8.2 6.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 ORY55329.1 - 4.5 7.5 7.7 0.44 10.7 3.1 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Snf7 PF03357.21 ORY55330.1 - 7.5e-15 55.0 6.0 7.5e-15 55.0 6.0 2.3 1 1 1 2 2 2 1 Snf7 YiiD_C PF09500.10 ORY55330.1 - 0.0077 16.1 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Putative thioesterase (yiiD_Cterm) DUF3584 PF12128.8 ORY55330.1 - 1.8 5.9 32.9 2.5 5.5 32.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Hid1 PF12722.7 ORY55330.1 - 9.1 4.3 12.6 11 4.0 12.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.32 ORY55331.1 - 4.5e-40 134.9 28.0 7e-06 26.7 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 ORY55331.1 - 5.5e-10 39.0 0.1 1.1e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 ORY55331.1 - 7e-09 35.9 0.7 1.8 8.9 0.0 5.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 ORY55331.1 - 1.5e-08 34.3 0.0 3.5e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ORY55331.1 - 0.00048 18.9 7.6 1.1 7.8 0.2 5.4 4 2 2 6 6 6 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ORY55331.1 - 0.11 11.3 1.8 0.57 9.0 0.1 2.6 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain DnaJ-X PF14308.6 ORY55333.1 - 0.041 13.3 1.2 0.062 12.7 1.2 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing SIR2 PF02146.17 ORY55334.1 - 8.7e-28 97.4 0.0 1e-15 58.1 0.0 2.4 2 0 0 2 2 2 2 Sir2 family BRF1 PF07741.13 ORY55334.1 - 1.6 9.2 5.4 4.4 7.7 5.4 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain YTH PF04146.15 ORY55336.1 - 3.4e-38 131.2 0.1 5.4e-38 130.5 0.1 1.3 1 1 0 1 1 1 1 YT521-B-like domain Aha1_N PF09229.11 ORY55337.1 - 1e-25 90.6 0.3 1.4e-25 90.1 0.3 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORY55337.1 - 6.8e-13 48.9 0.1 3.2e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein SKG6 PF08693.10 ORY55339.1 - 0.018 14.5 0.1 0.048 13.1 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 ORY55339.1 - 0.053 13.5 1.8 0.27 11.2 1.8 2.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TMEM154 PF15102.6 ORY55339.1 - 0.072 13.0 0.3 0.072 13.0 0.3 1.9 2 1 0 2 2 2 0 TMEM154 protein family Mid2 PF04478.12 ORY55339.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 ORY55339.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Fer2 PF00111.27 ORY55340.1 - 2.7e-10 40.1 0.2 4.5e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1727 PF08353.10 ORY55340.1 - 0.014 15.3 0.1 0.021 14.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) DUF4644 PF15486.6 ORY55340.1 - 0.086 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) NPR2 PF06218.11 ORY55341.1 - 3e-77 260.2 0.0 8.9e-36 123.6 0.0 3.6 1 1 2 3 3 3 3 Nitrogen permease regulator 2 Pro-NT_NN PF07421.11 ORY55341.1 - 0.037 14.3 0.0 0.06 13.6 0.0 1.2 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Mito_fiss_reg PF05308.11 ORY55341.1 - 2.6 8.1 0.0 2.6 8.1 0.0 3.2 2 1 1 3 3 3 0 Mitochondrial fission regulator DEAD PF00270.29 ORY55342.1 - 2.3e-26 92.6 0.1 5.7e-26 91.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sec63 PF02889.16 ORY55342.1 - 2.8e-22 79.1 0.0 4.4e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 ORY55342.1 - 2.3e-11 44.0 0.0 1.3e-10 41.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY55342.1 - 7.4e-10 39.1 0.0 2.4e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 ORY55342.1 - 0.00017 22.1 0.0 0.00057 20.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_19 PF13245.6 ORY55342.1 - 0.0098 16.2 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY55342.1 - 0.036 13.1 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4332 PF14229.6 ORY55342.1 - 0.041 14.1 0.1 0.23 11.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) AAA_30 PF13604.6 ORY55342.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_pol_lambd_f PF10391.9 ORY55342.1 - 0.14 12.0 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 ORY55342.1 - 0.19 12.0 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Pathogenicity locus UvrD-helicase PF00580.21 ORY55342.1 - 0.28 10.7 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Tim54 PF11711.8 ORY55343.1 - 3.9e-37 127.9 0.0 7e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DOPA_dioxygen PF08883.11 ORY55344.1 - 6.6e-43 145.3 0.0 8.2e-43 144.9 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family zf-C3HC4_2 PF13923.6 ORY55523.1 - 3e-14 52.6 15.4 6.6e-07 29.1 4.5 3.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY55523.1 - 7.7e-11 41.7 19.6 2.7e-06 27.2 3.9 3.4 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY55523.1 - 9.5e-09 35.5 16.2 1.6e-05 25.2 4.6 3.9 4 0 0 4 4 3 2 Ring finger domain zf-C3HC4_3 PF13920.6 ORY55523.1 - 4.4e-08 32.9 20.5 1.1e-05 25.2 2.1 3.1 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY55523.1 - 6.7e-07 29.5 13.2 0.00013 22.2 3.9 3.9 4 0 0 4 4 2 2 RING-H2 zinc finger domain zf-TRAF PF02176.18 ORY55523.1 - 3.3e-05 24.5 0.7 3.3e-05 24.5 0.7 5.3 6 1 0 6 6 4 1 TRAF-type zinc finger zf-TRAF_2 PF15965.5 ORY55523.1 - 3.4e-05 24.2 2.3 3.4e-05 24.2 2.3 4.6 3 2 1 4 4 4 1 TRAF-like zinc-finger Prok-RING_4 PF14447.6 ORY55523.1 - 4.3e-05 23.3 20.4 0.0039 17.0 1.8 3.9 4 0 0 4 4 4 2 Prokaryotic RING finger family 4 Sina PF03145.16 ORY55523.1 - 0.0024 17.9 27.1 0.004 17.1 1.9 5.1 3 2 2 5 5 5 2 Seven in absentia protein family zf-RING_UBOX PF13445.6 ORY55523.1 - 0.0035 17.3 15.6 0.11 12.5 2.3 3.7 3 1 1 4 4 4 2 RING-type zinc-finger zf-P11 PF03854.14 ORY55523.1 - 0.0085 15.7 7.5 0.58 9.9 0.5 2.8 2 0 0 2 2 2 2 P-11 zinc finger FeS_assembly_P PF01883.19 ORY55523.1 - 0.061 13.5 0.6 7.3 6.8 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein zf-RING_14 PF17978.1 ORY55523.1 - 0.073 13.5 10.1 2.3 8.7 2.1 3.8 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY55523.1 - 0.22 11.7 18.8 0.71 10.1 4.6 3.8 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY55523.1 - 0.33 11.0 27.4 0.036 14.0 3.5 3.7 4 0 0 4 4 4 0 zinc-RING finger domain Pox_A_type_inc PF04508.12 ORY55523.1 - 0.52 10.3 3.3 1.9 8.5 0.6 3.2 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat zf-RING_10 PF16685.5 ORY55523.1 - 1.1 9.5 13.7 1.1 9.4 0.7 2.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 ORY55523.1 - 7.3 6.7 19.8 0.82 9.8 0.4 3.8 4 0 0 4 4 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger UCH PF00443.29 ORY55524.1 - 4.2e-30 105.1 0.0 7.3e-30 104.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY55524.1 - 7.3e-08 32.4 0.2 3.5e-06 26.8 0.2 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ras PF00071.22 ORY55525.1 - 1.1e-49 168.2 0.0 1.3e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY55525.1 - 6.3e-30 103.9 0.0 9.9e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY55525.1 - 1.2e-09 37.9 0.0 1.6e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY55525.1 - 0.00039 19.8 0.0 0.00048 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY55525.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORY55525.1 - 0.011 15.0 0.6 0.76 8.9 0.1 2.4 2 1 0 2 2 2 0 G-protein alpha subunit RNA_helicase PF00910.22 ORY55525.1 - 0.014 15.8 0.1 0.12 12.8 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 ORY55525.1 - 0.023 14.2 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 ORY55525.1 - 0.023 14.2 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF5118 PF17162.4 ORY55525.1 - 0.037 13.8 0.1 0.071 12.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5118) AAA_24 PF13479.6 ORY55525.1 - 0.052 13.3 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY55525.1 - 0.083 13.3 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 ORY55525.1 - 0.094 12.7 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORY55525.1 - 0.1 12.5 0.0 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 ORY55525.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain STAS PF01740.21 ORY55525.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 STAS domain Septin PF00735.18 ORY55525.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.4 1 0 0 1 1 1 0 Septin zf-C3HC4_3 PF13920.6 ORY55526.1 - 4.3e-06 26.5 7.9 4.3e-06 26.5 7.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY55526.1 - 9.2e-06 25.4 9.5 9.2e-06 25.4 9.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY55526.1 - 2.3e-05 24.6 9.2 2.3e-05 24.6 9.2 2.5 3 0 0 3 3 1 1 Ring finger domain DUF1644 PF07800.12 ORY55526.1 - 5.3e-05 23.3 3.8 5.3e-05 23.3 3.8 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1644) Sina PF03145.16 ORY55526.1 - 0.00019 21.5 11.8 0.0053 16.7 0.9 2.9 1 1 2 3 3 3 2 Seven in absentia protein family zf-C3HC4 PF00097.25 ORY55526.1 - 0.0012 18.7 9.5 0.0038 17.0 9.5 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 ORY55526.1 - 0.0092 16.6 11.1 0.031 15.0 1.6 4.8 2 2 2 4 4 4 2 TRAF-type zinc finger zf-RING_5 PF14634.6 ORY55526.1 - 0.01 15.8 8.2 0.01 15.8 8.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_14 PF17978.1 ORY55526.1 - 0.031 14.7 2.8 0.031 14.7 2.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 ORY55526.1 - 0.041 13.9 5.2 0.13 12.3 5.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger His_Me_b4a2 PF18275.1 ORY55526.1 - 0.044 13.9 4.4 0.16 12.1 4.0 2.2 2 1 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain zf-RING_6 PF14835.6 ORY55526.1 - 0.058 13.3 3.7 0.2 11.5 3.7 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY55526.1 - 0.11 12.8 10.0 3.8 7.9 10.0 2.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain DiS_P_DiS PF06750.13 ORY55526.1 - 0.35 11.0 6.9 0.77 9.9 6.9 1.7 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF1992 PF09350.10 ORY55527.1 - 7.4e-21 74.1 2.7 1.1e-20 73.6 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1992) SNO PF01174.19 ORY55528.1 - 1.2e-44 152.4 0.0 3.2e-42 144.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORY55528.1 - 2.1e-07 30.8 0.0 3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SOR_SNZ PF01680.17 ORY55529.1 - 2.8e-107 357.2 5.3 3.5e-107 356.9 5.3 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 ORY55529.1 - 1.4e-07 31.1 11.2 5.6e-07 29.1 1.0 2.6 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 ORY55529.1 - 3.4e-05 23.1 0.2 0.052 12.6 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ORY55529.1 - 0.00032 20.2 0.3 0.068 12.6 0.0 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 ORY55529.1 - 0.0011 18.1 0.3 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 ORY55529.1 - 0.0049 16.1 0.6 0.033 13.4 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 ORY55529.1 - 0.018 14.4 5.9 0.21 11.0 0.3 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase TetR_C_27 PF17935.1 ORY55529.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Cnn_1N PF07989.11 ORY55530.1 - 1.3e-25 89.4 7.8 1.3e-25 89.4 7.8 13.0 9 2 5 14 14 14 3 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 ORY55530.1 - 0.00014 22.1 7.1 0.00014 22.1 7.1 11.2 11 4 1 12 12 12 2 Micro-tubular organiser Mto1 C-term Mto2-binding region TetR_C_36 PF18598.1 ORY55530.1 - 0.0069 16.3 0.2 0.025 14.6 0.2 2.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain DUF3966 PF13110.6 ORY55530.1 - 0.027 14.4 0.6 0.027 14.4 0.6 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3966) Oxidored_nitro PF00148.19 ORY55530.1 - 0.55 8.9 3.3 1.7 7.3 3.3 1.8 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase SAVED PF18145.1 ORY55530.1 - 8 6.2 6.9 1.1 9.0 1.5 2.4 2 0 0 2 2 2 0 SMODS-associated and fused to various effectors sensor domain SUR7 PF06687.12 ORY55531.1 - 9.5e-19 67.9 4.9 1.2e-18 67.6 4.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 ORY55531.1 - 0.00015 21.6 2.2 0.00015 21.6 2.2 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 ORY55531.1 - 0.69 9.8 11.0 0.093 12.6 3.6 2.6 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family L_HMGIC_fpl PF10242.9 ORY55531.1 - 1.4 9.1 10.0 1.6 8.9 2.6 2.9 3 0 0 3 3 3 0 Lipoma HMGIC fusion partner-like protein DUF4336 PF14234.6 ORY55532.1 - 4.6e-15 55.6 0.1 5e-09 35.8 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Gpr1_Fun34_YaaH PF01184.19 ORY55533.1 - 9.4e-82 273.6 20.9 1.2e-81 273.2 20.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SOG2 PF10428.9 ORY55534.1 - 0.2 10.8 30.3 0.34 10.1 10.1 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein GMC_oxred_N PF00732.19 ORY55535.1 - 9.5e-69 232.0 0.0 1.2e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY55535.1 - 3.1e-38 131.5 0.0 5.4e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY55535.1 - 0.0004 19.5 0.1 0.0006 19.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY55535.1 - 0.0013 17.9 0.1 0.0072 15.5 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY55535.1 - 0.0015 18.7 0.1 0.0036 17.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY55535.1 - 0.032 13.8 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 ORY55535.1 - 0.16 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family zf-TRAF PF02176.18 ORY55536.1 - 1.7e-06 28.6 10.6 5.8e-05 23.7 3.4 2.7 1 1 1 2 2 2 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 ORY55536.1 - 0.0021 18.5 6.4 0.0021 18.5 6.4 2.5 1 1 2 3 3 3 1 TRAF-like zinc-finger PriC PF07445.12 ORY55536.1 - 0.017 15.0 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC DUF1635 PF07795.11 ORY55536.1 - 0.096 12.5 0.3 0.16 11.8 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) DUF1664 PF07889.12 ORY55536.1 - 0.2 11.7 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sina PF03145.16 ORY55536.1 - 1.3 8.9 13.3 2.7 7.9 2.3 2.7 1 1 2 3 3 3 0 Seven in absentia protein family Lactamase_B_2 PF12706.7 ORY55537.1 - 1.4e-26 93.3 0.0 2.2e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY55537.1 - 2.9e-05 24.2 0.4 5.6e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY55538.1 - 7.8e-24 84.3 0.0 4.3e-23 81.9 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY55538.1 - 3.5e-05 23.9 2.6 0.00016 21.7 2.6 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY55538.1 - 0.00066 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain BTB PF00651.31 ORY55540.1 - 0.0017 18.5 0.0 0.29 11.4 0.0 2.9 3 0 0 3 3 3 2 BTB/POZ domain Pkinase PF00069.25 ORY55544.1 - 7.7e-30 104.1 0.0 1.1e-18 67.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY55544.1 - 4.7e-13 49.0 0.0 7.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Gram_pos_anchor PF00746.21 ORY55545.1 - 0.19 11.7 1.1 0.3 11.1 1.1 1.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SOR_SNZ PF01680.17 ORY55546.1 - 2.8e-107 357.2 5.3 3.5e-107 356.9 5.3 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 ORY55546.1 - 1.4e-07 31.1 11.2 5.6e-07 29.1 1.0 2.6 1 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 ORY55546.1 - 3.4e-05 23.1 0.2 0.052 12.6 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 ORY55546.1 - 0.00032 20.2 0.3 0.068 12.6 0.0 2.3 2 0 0 2 2 2 2 Histidine biosynthesis protein NanE PF04131.14 ORY55546.1 - 0.0011 18.1 0.3 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 ORY55546.1 - 0.0049 16.1 0.6 0.033 13.4 0.0 2.3 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 ORY55546.1 - 0.018 14.4 5.9 0.21 11.0 0.3 2.4 2 0 0 2 2 2 0 Nitronate monooxygenase TetR_C_27 PF17935.1 ORY55546.1 - 0.055 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SNO PF01174.19 ORY55547.1 - 5e-44 150.4 0.0 2.4e-36 125.4 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORY55547.1 - 4.5e-07 29.6 0.0 6.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF1681 PF07933.14 ORY55548.1 - 3.3e-52 176.1 0.0 3.9e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF2300 PF10062.9 ORY55548.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) Alkyl_sulf_dimr PF14863.6 ORY55549.1 - 0.037 14.5 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Peroxin-3 PF04882.12 ORY55550.1 - 7.1e-132 440.7 0.2 9.6e-130 433.7 0.2 2.0 1 1 0 1 1 1 1 Peroxin-3 eIF-3c_N PF05470.12 ORY55550.1 - 0.0067 14.8 4.6 0.009 14.4 4.6 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Draxin PF15550.6 ORY55550.1 - 0.062 13.2 3.2 0.11 12.4 3.2 1.3 1 0 0 1 1 1 0 Draxin NPR3 PF03666.13 ORY55550.1 - 0.08 11.7 3.8 0.15 10.9 3.8 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ATP-synt_E PF05680.12 ORY55550.1 - 1.1 9.7 9.0 2.6 8.5 9.0 1.6 1 0 0 1 1 1 0 ATP synthase E chain MCPVI PF02993.14 ORY55550.1 - 1.5 8.6 10.4 3 7.6 4.7 2.3 2 0 0 2 2 2 0 Minor capsid protein VI Plasmodium_Vir PF05795.11 ORY55550.1 - 1.8 7.9 4.8 3 7.2 4.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2052 PF09747.9 ORY55550.1 - 3 7.9 16.8 0.35 11.0 11.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1682 PF07946.14 ORY55550.1 - 4.6 6.4 9.3 6.9 5.8 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MCM_bind PF09739.9 ORY55550.1 - 5.9 5.2 9.7 11 4.4 9.7 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NARP1 PF12569.8 ORY55550.1 - 6.1 5.6 9.7 8.8 5.1 9.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 ORY55550.1 - 8.2 6.2 14.0 5.6 6.7 8.7 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Adenine_glyco PF03352.13 ORY55551.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase KilA-N PF04383.13 ORY55552.1 - 0.0072 16.2 0.0 0.13 12.1 0.0 2.0 1 1 1 2 2 2 2 KilA-N domain Mito_carr PF00153.27 ORY55553.1 - 5.7e-58 192.9 1.3 1e-18 67.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIE-A_C PF11521.8 ORY55554.1 - 0.74 10.1 7.3 1.5 9.2 7.3 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Med6 PF04934.14 ORY55555.1 - 7e-41 139.1 0.0 9.3e-41 138.7 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Ribosomal_60s PF00428.19 ORY55555.1 - 0.7 10.5 14.1 2.4 8.8 4.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein CAP_N PF01213.19 ORY55555.1 - 4.2 6.7 6.7 7.1 6.0 6.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Bac_luciferase PF00296.20 ORY55556.1 - 2.1e-56 191.6 0.1 3.2e-56 191.0 0.1 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase PX PF00787.24 ORY55557.1 - 8.9e-26 90.1 0.0 1.3e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 PX domain Adeno_E1B_19K PF01691.16 ORY55557.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen NAD_binding_9 PF13454.6 ORY55557.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding RRM_1 PF00076.22 ORY55558.1 - 3e-10 39.8 0.0 3.4e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ORY55558.1 - 1.6e-08 35.0 5.7 1.6e-08 35.0 5.7 2.8 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 SWIM PF04434.17 ORY55719.1 - 0.00026 20.6 2.1 0.00047 19.8 2.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger Metallophos PF00149.28 ORY55720.1 - 6.5e-35 121.5 0.1 8.8e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MAP70 PF07058.11 ORY55721.1 - 4 6.1 6.6 4.9 5.8 6.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein 70 zf-C2H2 PF00096.26 ORY55723.1 - 3.2e-11 43.0 7.5 7.4e-06 26.1 1.0 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY55723.1 - 1.3e-08 34.9 8.5 2e-05 24.8 1.5 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY55723.1 - 2.7e-06 27.8 6.3 0.0033 18.1 0.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY55723.1 - 0.0021 18.0 4.0 0.01 15.8 2.3 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY55723.1 - 0.0031 17.8 0.9 0.0085 16.4 0.9 1.7 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY55723.1 - 0.032 14.4 0.5 4.5 7.4 0.0 2.0 1 1 1 2 2 2 0 Aberrant zinc-finger ALAD PF00490.21 ORY55724.1 - 2.3e-123 411.4 0.0 2.7e-123 411.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Bax1-I PF01027.20 ORY55725.1 - 7.8e-42 143.4 25.9 9.2e-42 143.2 25.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pkinase PF00069.25 ORY55726.1 - 2.2e-42 145.2 0.0 1.7e-41 142.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY55726.1 - 1.1e-21 77.3 0.0 7.1e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ORY55726.1 - 0.005 16.2 0.1 0.0083 15.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY55726.1 - 0.0053 16.1 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like MOZ_SAS PF01853.18 ORY55728.1 - 3.4e-83 277.7 0.2 4.8e-83 277.2 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORY55728.1 - 7.4e-24 83.1 1.3 1.5e-23 82.1 1.3 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 ORY55728.1 - 1.3e-19 69.9 0.0 3.7e-19 68.4 0.0 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.25 ORY55728.1 - 0.00084 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY55728.1 - 0.002 18.5 0.0 0.0041 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HTH_11 PF08279.12 ORY55728.1 - 0.087 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 HTH domain DUF3123 PF11321.8 ORY55728.1 - 0.14 12.8 1.0 0.4 11.4 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) YppG PF14179.6 ORY55730.1 - 0.14 12.9 0.4 0.36 11.6 0.1 1.9 2 0 0 2 2 2 0 YppG-like protein MGC-24 PF05283.11 ORY55730.1 - 0.29 11.6 7.5 0.66 10.4 7.5 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Macoilin PF09726.9 ORY55730.1 - 1.3 7.5 5.7 1.6 7.2 5.7 1.1 1 0 0 1 1 1 0 Macoilin family HSD3 PF15244.6 ORY55730.1 - 2.3 7.6 9.6 3.4 7.1 9.6 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 SNF2_N PF00176.23 ORY55731.1 - 6.8e-35 120.4 0.8 8.9e-29 100.3 0.0 2.9 1 1 1 2 2 2 2 SNF2 family N-terminal domain DUF4208 PF13907.6 ORY55731.1 - 4.4e-23 81.5 5.8 4.5e-23 81.5 3.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 ORY55731.1 - 5.1e-22 77.5 3.6 3.5e-12 46.0 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 ORY55731.1 - 1.5e-18 67.2 0.0 3.6e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY55731.1 - 5.7e-07 29.0 0.0 1.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 ORY55731.1 - 5.8e-06 26.6 0.1 5.8e-06 26.6 0.1 3.9 3 1 1 4 4 4 1 Chromodomain helicase DNA-binding domain 1 ERCC3_RAD25_C PF16203.5 ORY55731.1 - 0.0012 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 ORY55731.1 - 0.0019 18.2 0.3 0.024 14.6 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 ORY55731.1 - 0.015 15.9 0.4 0.015 15.9 0.4 2.9 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 CHDCT2 PF08074.11 ORY55731.1 - 0.018 15.3 0.1 0.087 13.0 0.0 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Myb_DNA-binding PF00249.31 ORY55731.1 - 0.019 15.1 0.8 0.06 13.6 0.8 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain PWWP PF00855.17 ORY55732.1 - 9.9e-22 77.2 0.0 3.8e-21 75.3 0.0 2.0 1 0 0 1 1 1 1 PWWP domain PI3K_1B_p101 PF10486.9 ORY55732.1 - 1 7.1 3.5 1.2 6.9 3.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ATP-synt_DE_N PF02823.16 ORY55733.1 - 4.6e-09 36.0 0.1 9.1e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain TFIIA PF03153.13 ORY55734.1 - 1.3e-48 167.1 13.1 2e-29 103.8 12.7 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 ORY55734.1 - 2.5 6.1 5.3 3.1 5.8 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 ORY55735.1 - 8.2e-67 225.3 0.0 1e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY55735.1 - 2.6e-29 102.3 0.0 3.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY55735.1 - 5.1e-06 26.0 0.0 7.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY55735.1 - 0.096 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Mito_carr PF00153.27 ORY55736.1 - 1.1e-49 166.3 7.0 1.1e-19 70.2 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 ORY55736.1 - 0.14 11.3 2.6 0.49 9.5 0.1 2.5 3 0 0 3 3 3 0 Gammaproteobacterial serine protease CorA PF01544.18 ORY55737.1 - 1.4e-34 119.8 5.3 4.5e-29 101.7 2.4 2.7 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Glyco_transf_20 PF00982.21 ORY55738.1 - 6.4e-140 467.0 0.0 8.3e-140 466.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY55738.1 - 5.1e-68 228.7 0.0 8.1e-68 228.0 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY55738.1 - 0.00013 21.8 0.0 0.0019 18.0 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 ORY55738.1 - 0.056 13.0 0.0 9.4 5.7 0.0 2.5 2 1 0 2 2 2 0 Glycosyl transferases group 1 Ac110_PIF PF07280.11 ORY55738.1 - 0.29 10.9 0.9 0.6 9.9 0.9 1.4 1 0 0 1 1 1 0 Per os infectivity factor AC110 YppG PF14179.6 ORY55739.1 - 0.36 11.6 0.1 0.36 11.6 0.1 2.2 3 0 0 3 3 3 0 YppG-like protein Macoilin PF09726.9 ORY55739.1 - 1.2 7.6 5.8 1.4 7.4 5.8 1.1 1 0 0 1 1 1 0 Macoilin family MGC-24 PF05283.11 ORY55739.1 - 1.8 9.0 8.2 3.7 8.0 8.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HSD3 PF15244.6 ORY55739.1 - 2 7.8 9.2 3 7.3 9.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 PALP PF00291.25 ORY55741.1 - 5.4e-61 206.6 0.1 6.6e-61 206.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L11 PF00298.19 ORY55743.1 - 4.6e-26 91.1 0.1 6.6e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 ORY55743.1 - 6.7e-26 89.9 0.5 1.1e-25 89.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain UBA PF00627.31 ORY55744.1 - 1.2e-23 82.6 5.2 1.6e-11 43.9 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 ORY55744.1 - 1.9e-21 75.5 5.5 3.6e-21 74.7 5.5 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 ORY55744.1 - 1.6e-18 66.2 0.1 2.3e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY55744.1 - 1.7e-07 30.9 2.4 2e-07 30.8 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 ORY55744.1 - 7.4e-06 25.7 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rap1_C PF11626.8 ORY55744.1 - 0.014 15.5 0.0 7.7 6.7 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1421 PF07223.11 ORY55744.1 - 0.087 12.7 1.0 10 6.1 0.3 2.4 2 0 0 2 2 2 0 UBA-like domain (DUF1421) WIYLD PF10440.9 ORY55744.1 - 0.19 11.5 0.3 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF3306 PF11748.8 ORY55744.1 - 9.2 7.2 9.1 1.1 10.2 2.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) Fe-S_biosyn PF01521.20 ORY55745.1 - 2.2e-21 76.1 0.0 2.8e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis CPSF_A PF03178.15 ORY55746.1 - 2.4e-76 257.1 0.0 6e-76 255.8 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 ORY55746.1 - 1.6e-11 43.6 0.0 2e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term MGC-24 PF05283.11 ORY55748.1 - 0.45 11.0 8.2 0.9 10.0 8.2 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Macoilin PF09726.9 ORY55748.1 - 0.89 8.0 6.3 1 7.8 6.3 1.1 1 0 0 1 1 1 0 Macoilin family RNase_PH PF01138.21 ORY55749.1 - 2e-31 109.2 0.0 3.3e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 IFRD PF05004.13 ORY55749.1 - 0.22 10.6 0.3 3.7 6.6 0.0 2.0 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Ccdc124 PF06244.12 ORY55750.1 - 1.3e-25 90.4 10.9 5e-25 88.5 10.9 1.9 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Hexokinase_2 PF03727.16 ORY55751.1 - 7.4e-83 277.7 0.0 9.8e-83 277.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY55751.1 - 1.2e-67 227.7 0.0 2.3e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase DUF1977 PF09320.11 ORY55752.1 - 1.8e-25 89.2 0.0 3.9e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 ORY55752.1 - 1.2e-22 79.7 0.0 2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pro_isomerase PF00160.21 ORY55754.1 - 5.5e-47 160.0 0.1 6.3e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORY55948.1 - 2.2e-15 56.2 0.1 3.8e-06 26.6 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY55948.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif RRM_Rrp7 PF17799.1 ORY55948.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Rrp7 RRM-like N-terminal domain RNA_pol_Rbc25 PF08292.12 ORY55948.1 - 0.066 13.5 3.2 4.1 7.6 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 DUF3976 PF13121.6 ORY55949.1 - 0.73 10.0 0.0 0.73 10.0 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3976) PHY PF00360.20 ORY55950.1 - 7.8e-26 90.5 0.0 1.6e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 ORY55950.1 - 4.1e-17 62.7 0.0 9.3e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY55950.1 - 1e-15 57.8 0.0 4e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY55950.1 - 1.4e-11 44.2 2.0 4.8e-11 42.5 2.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 ORY55950.1 - 2.9e-10 40.9 0.1 1e-09 39.1 0.0 2.0 2 0 0 2 2 2 1 GAF domain PAS_2 PF08446.11 ORY55950.1 - 1.3e-09 38.6 0.0 1e-08 35.8 0.0 2.5 2 0 0 2 2 2 1 PAS fold CwfJ_C_2 PF04676.14 ORY55951.1 - 9.6e-34 116.2 0.1 9.6e-34 116.2 0.1 2.2 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 ORY55951.1 - 3.8e-29 101.0 0.0 5.7e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 FMN_red PF03358.15 ORY55952.1 - 4.3e-22 78.5 0.0 8.3e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Mitoc_L55 PF09776.9 ORY55952.1 - 0.27 11.0 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 TetR_C_28 PF17937.1 ORY55953.1 - 0.068 13.6 1.4 3.2 8.3 0.4 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CH PF00307.31 ORY55954.1 - 6.2e-49 164.7 0.0 1.2e-26 93.0 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY55954.1 - 2.8e-10 39.9 0.0 2.5e-07 30.4 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EFhand_Ca_insen PF08726.10 ORY55954.1 - 3.9e-10 39.7 0.0 1.1e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand Spectrin PF00435.21 ORY55954.1 - 0.0013 19.2 0.5 1.7 9.2 0.5 2.9 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.32 ORY55954.1 - 0.011 15.2 0.9 0.43 10.2 0.1 2.8 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 ORY55954.1 - 0.04 13.9 1.2 0.29 11.2 0.5 2.6 2 0 0 2 2 2 0 EF-hand domain Baculo_PEP_C PF04513.12 ORY55954.1 - 0.39 10.7 2.3 0.81 9.7 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_8 PF13833.6 ORY55954.1 - 0.49 10.3 1.7 12 5.9 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair HSF_DNA-bind PF00447.17 ORY55955.1 - 1.6e-15 57.5 1.5 2.4e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 HSF-type DNA-binding TSSC4 PF15264.6 ORY55955.1 - 0.66 10.3 4.9 5.5 7.3 0.4 2.6 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 TFIIA PF03153.13 ORY55955.1 - 8.2 6.3 16.5 11 5.9 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit His_Phos_2 PF00328.22 ORY55956.1 - 2.2e-32 112.8 0.0 3.8e-32 112.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) p450 PF00067.22 ORY55957.1 - 1.9e-60 204.9 0.0 2.5e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N PF02798.20 ORY55958.1 - 1.8e-18 66.6 0.0 3.5e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY55958.1 - 8.8e-12 45.1 0.0 1.6e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY55958.1 - 1e-11 45.0 0.0 2.1e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY55958.1 - 4.4e-11 43.0 0.0 7.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY55958.1 - 5.2e-11 42.6 0.1 1.7e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY55958.1 - 1e-05 25.4 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Atg8 PF02991.16 ORY55958.1 - 0.045 13.9 0.0 0.16 12.1 0.0 1.9 2 1 1 3 3 3 0 Autophagy protein Atg8 ubiquitin like GST_N_4 PF17172.4 ORY55958.1 - 0.16 12.8 0.0 0.46 11.3 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain FAD_binding_4 PF01565.23 ORY55959.1 - 1.4e-24 86.4 0.1 2.9e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 ORY55959.1 - 7.2e-15 55.3 0.0 1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF4276 PF14103.6 ORY55959.1 - 0.2 11.9 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) POB3_N PF17292.2 ORY55960.1 - 1.5e-29 102.3 0.1 2.1e-27 95.4 0.1 2.5 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 ORY55960.1 - 1.4e-25 89.5 0.2 8.1e-23 80.7 0.0 3.1 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 ORY55960.1 - 7.4e-19 67.4 0.0 4.4e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) TLP-20 PF06088.11 ORY55960.1 - 0.0021 18.0 1.9 0.026 14.4 0.3 2.4 2 0 0 2 2 2 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) UPF0029 PF01205.19 ORY55961.1 - 4.8e-22 78.3 0.0 9.3e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Mito_fiss_reg PF05308.11 ORY55961.1 - 0.95 9.5 7.1 0.16 12.1 0.6 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator Yippee-Mis18 PF03226.14 ORY55963.1 - 0.14 12.4 0.2 23 5.3 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc-ribbons_6 PF07191.12 ORY55963.1 - 0.26 11.3 3.4 0.32 11.0 1.6 2.0 2 0 0 2 2 2 0 zinc-ribbons MFS_1 PF07690.16 ORY55965.1 - 1.3e-30 106.5 70.9 4.7e-27 94.8 43.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.20 ORY55965.1 - 0.004 15.5 0.0 0.004 15.5 0.0 2.4 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sec62 PF03839.16 ORY55965.1 - 3.2 7.2 4.6 5.9 6.3 4.6 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Perilipin PF03036.16 ORY55966.1 - 0.051 12.6 0.9 0.073 12.1 0.9 1.1 1 0 0 1 1 1 0 Perilipin family PI31_Prot_N PF11566.8 ORY55967.1 - 2.5e-37 128.2 0.0 3e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 ORY55967.1 - 7.1e-07 30.3 16.8 7.1e-07 30.3 16.8 2.6 2 1 1 3 3 3 1 PI31 proteasome regulator p450 PF00067.22 ORY55968.1 - 2.1e-65 221.3 0.0 2.6e-65 221.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 ORY55969.1 - 1.9e-07 30.9 1.6 3.6e-07 30.0 0.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY55969.1 - 0.0008 19.7 0.4 2.7 8.5 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY55969.1 - 0.25 11.2 1.5 4.1 7.4 1.5 2.6 1 1 0 1 1 1 0 F-box domain Zn_clus PF00172.18 ORY55970.1 - 1.6e-07 31.3 15.3 3.7e-07 30.1 15.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1658 PF07871.11 ORY55971.1 - 0.26 11.3 2.4 2.2 8.3 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) VSP PF03302.13 ORY55972.1 - 0.35 9.7 7.7 0.67 8.7 7.7 1.5 1 1 0 1 1 1 0 Giardia variant-specific surface protein vATP-synt_AC39 PF01992.16 ORY55973.1 - 8.4e-114 380.6 0.0 9.4e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SLC3A2_N PF16028.5 ORY56171.1 - 0.49 10.0 0.1 0.49 10.0 0.1 2.5 2 1 1 3 3 3 0 Solute carrier family 3 member 2 N-terminus SAD_SRA PF02182.17 ORY56172.1 - 4.3e-45 153.2 0.0 4.8e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 SAD/SRA domain DUF4854 PF16146.5 ORY56172.1 - 0.16 12.3 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) Hva1_TUDOR PF11160.8 ORY56173.1 - 6.3e-12 45.5 2.4 6.3e-12 45.5 2.4 2.5 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain AMP-binding PF00501.28 ORY56174.1 - 4.5e-74 249.5 0.4 5.4e-74 249.3 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY56174.1 - 2.5e-20 73.2 0.0 6.4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AAA_18 PF13238.6 ORY56178.1 - 3.1e-23 82.7 0.1 5.2e-23 82.0 0.0 1.4 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 ORY56178.1 - 6.2e-05 23.2 0.2 0.018 15.2 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY56178.1 - 8.9e-05 22.9 0.0 0.00012 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 ORY56178.1 - 0.00018 21.8 0.1 0.00094 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 ORY56178.1 - 0.00046 19.7 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 ORY56178.1 - 0.00083 19.3 0.1 0.0032 17.4 0.0 1.8 2 0 0 2 2 2 1 NTPase DUF2075 PF09848.9 ORY56178.1 - 0.00091 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 ORY56178.1 - 0.001 19.3 0.0 0.0022 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY56178.1 - 0.0012 19.2 0.0 0.0032 17.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.22 ORY56178.1 - 0.0025 18.0 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.6 ORY56178.1 - 0.0027 18.1 0.0 0.011 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY56178.1 - 0.0038 17.6 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY56178.1 - 0.0046 16.3 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SSE PF00437.20 ORY56178.1 - 0.0055 15.8 0.0 0.011 14.8 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ATPase PF06745.13 ORY56178.1 - 0.0079 15.6 0.1 0.038 13.3 0.0 1.9 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.22 ORY56178.1 - 0.0083 15.3 0.0 0.024 13.8 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TniB PF05621.11 ORY56178.1 - 0.0095 15.4 0.1 0.034 13.5 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein AAA_5 PF07728.14 ORY56178.1 - 0.0099 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.9 ORY56178.1 - 0.01 14.8 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 ORY56178.1 - 0.011 16.2 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 ORY56178.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Thymidylate_kin PF02223.17 ORY56178.1 - 0.012 15.2 0.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.6 ORY56178.1 - 0.018 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY56178.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.21 ORY56178.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 ORY56178.1 - 0.024 14.3 0.1 0.053 13.2 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 ORY56178.1 - 0.027 14.0 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ADK PF00406.22 ORY56178.1 - 0.027 14.6 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase AAA_24 PF13479.6 ORY56178.1 - 0.032 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY56178.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase CobU PF02283.16 ORY56178.1 - 0.082 12.5 0.2 12 5.5 0.3 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase dNK PF01712.19 ORY56178.1 - 0.1 12.5 0.2 2.8 7.7 0.0 2.2 1 1 0 2 2 2 0 Deoxynucleoside kinase T4_Rnl2_C PF18043.1 ORY56178.1 - 0.11 12.7 1.2 0.17 12.1 0.2 1.8 2 0 0 2 2 1 0 T4 RNA ligase 2 C-terminal Ploopntkinase2 PF18747.1 ORY56178.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 AAA_14 PF13173.6 ORY56178.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORY56178.1 - 0.18 11.6 0.2 0.44 10.3 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TMEM154 PF15102.6 ORY56179.1 - 2.7e-05 24.1 0.6 2.7e-05 24.1 0.6 2.3 2 0 0 2 2 2 1 TMEM154 protein family SKG6 PF08693.10 ORY56179.1 - 0.00039 19.8 0.1 0.00095 18.5 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DAG1 PF05454.11 ORY56179.1 - 0.0067 15.8 0.0 0.0067 15.8 0.0 1.6 2 0 0 2 2 2 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Mid2 PF04478.12 ORY56179.1 - 0.012 15.4 0.1 0.012 15.4 0.1 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 ORY56179.1 - 0.021 14.6 0.1 0.049 13.4 0.1 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Plasmodium_Vir PF05795.11 ORY56179.1 - 0.024 14.1 2.2 0.039 13.4 2.2 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein DUF4448 PF14610.6 ORY56179.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PRR22 PF15776.5 ORY56179.1 - 0.12 11.7 0.1 0.12 11.7 0.1 3.0 3 0 0 3 3 3 0 Proline-rich protein family 22 CCDC84 PF14968.6 ORY56179.1 - 0.21 11.2 4.0 0.83 9.2 4.0 1.9 1 1 0 1 1 1 0 Coiled coil protein 84 Lin-8 PF03353.15 ORY56179.1 - 2 7.9 5.5 0.29 10.6 1.1 1.8 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist Pal1 PF08316.11 ORY56181.1 - 2e-09 38.3 0.1 2e-09 38.3 0.1 2.6 3 1 0 3 3 3 1 Pal1 cell morphology protein DUF3827 PF12877.7 ORY56181.1 - 0.061 11.7 0.3 0.074 11.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Apt1 PF10351.9 ORY56181.1 - 1.3 7.8 3.9 1.3 7.8 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ras PF00071.22 ORY56182.1 - 2e-57 193.3 0.0 2.5e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY56182.1 - 4.5e-35 120.5 0.0 6.8e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY56182.1 - 1.6e-17 63.5 0.0 3.7e-16 59.1 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY56182.1 - 2.8e-06 26.9 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY56182.1 - 3.7e-06 27.0 0.0 6.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY56182.1 - 2.1e-05 24.2 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORY56182.1 - 0.0012 19.3 0.2 0.0018 18.7 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY56182.1 - 0.018 14.9 0.0 1.9 8.4 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase TniB PF05621.11 ORY56182.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DSPc PF00782.20 ORY56183.1 - 3.4e-22 78.7 0.0 6.4e-13 48.7 0.0 3.2 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY56183.1 - 8.9e-05 22.2 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY56183.1 - 0.23 11.6 0.1 0.45 10.6 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Pmp3 PF01679.17 ORY56184.1 - 2.3e-06 27.7 14.4 3.1e-06 27.3 14.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF5560 PF17715.1 ORY56184.1 - 0.33 10.4 4.0 0.43 10.0 4.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Cation_ATPase_C PF00689.21 ORY56184.1 - 4.8 6.8 8.4 6 6.5 8.4 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Ion_trans_2 PF07885.16 ORY56185.1 - 6.3e-28 96.6 26.7 2.4e-15 56.3 9.1 2.8 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 ORY56185.1 - 0.00037 19.8 16.9 0.015 14.5 0.9 3.0 2 1 0 2 2 2 2 Ion transport protein IRK PF01007.20 ORY56185.1 - 0.49 10.2 5.9 2.3 8.0 0.8 2.9 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain DUF4172 PF13776.6 ORY56186.1 - 0.09 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) zf-MYND PF01753.18 ORY56187.1 - 4.2e-06 26.8 9.6 4.2e-06 26.8 9.6 1.6 2 0 0 2 2 2 1 MYND finger DUF2256 PF10013.9 ORY56187.1 - 0.028 14.6 5.7 0.028 14.6 5.7 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Clat_adaptor_s PF01217.20 ORY56188.1 - 3.6e-43 146.9 0.1 2.2e-42 144.4 0.1 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_60s PF00428.19 ORY56190.1 - 2.4 8.8 7.0 0.52 10.9 1.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein HEAT PF02985.22 ORY56191.1 - 3.6e-39 129.4 26.5 0.0077 16.4 0.1 13.7 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 ORY56191.1 - 8.7e-36 122.2 14.3 2e-11 44.1 0.0 6.9 2 1 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 ORY56191.1 - 1.1e-13 51.4 17.5 0.00028 21.3 0.5 8.8 7 2 2 9 9 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY56191.1 - 7.8e-12 45.6 1.6 0.037 14.6 0.1 7.2 5 3 4 9 9 9 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY56191.1 - 1.3e-07 31.8 11.4 0.32 11.0 0.3 5.6 4 2 1 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY56191.1 - 2.9e-05 22.9 4.5 7.5e-05 21.5 0.4 2.7 2 1 1 3 3 3 2 Adaptin N terminal region Arm PF00514.23 ORY56191.1 - 5e-05 23.2 2.6 11 6.3 0.0 6.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 ORY56191.1 - 0.016 15.4 6.2 22 5.2 0.1 5.0 5 1 2 7 7 6 0 Required for nuclear transport of RNA pol II C-terminus 1 V_ATPase_I_N PF18670.1 ORY56191.1 - 0.096 13.1 0.4 2.2 8.8 0.0 2.7 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain V-ATPase_H_N PF03224.14 ORY56191.1 - 0.17 11.1 1.4 1.6 7.9 0.0 2.8 2 1 0 3 3 3 0 V-ATPase subunit H IFRD PF05004.13 ORY56191.1 - 1.1 8.3 5.4 7.6 5.5 0.8 4.0 3 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Vac_ImportDeg PF09783.9 ORY56192.1 - 2e-24 86.2 0.0 2.5e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Vacuolar import and degradation protein UreD PF01774.17 ORY56193.1 - 9.5e-61 205.4 0.0 1.1e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Mg_trans_NIPA PF05653.14 ORY56194.1 - 3.4e-24 85.5 14.0 5.7e-13 48.6 2.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORY56194.1 - 0.0089 16.2 5.0 0.0089 16.2 5.0 2.8 3 0 0 3 3 3 1 EamA-like transporter family DUF3682 PF12446.8 ORY56195.1 - 0.0023 18.4 0.4 0.0029 18.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) Kinesin_assoc PF16183.5 ORY56195.1 - 0.0048 17.1 0.2 0.0053 16.9 0.2 1.2 1 0 0 1 1 1 1 Kinesin-associated Endonuc_Holl PF10107.9 ORY56195.1 - 0.47 10.3 5.5 0.65 9.8 5.5 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase AP_endonuc_2 PF01261.24 ORY56196.1 - 9.7e-33 113.4 0.0 1.3e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.11 ORY56197.1 - 3.5e-11 43.2 0.0 6.5e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 ORY56197.1 - 0.0036 17.4 0.0 0.0078 16.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApeA_NTD1 PF18862.1 ORY56197.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 ApeA N-terminal domain 1 SnoaL_4 PF13577.6 ORY56198.1 - 0.0001 22.4 0.0 0.00014 22.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DHquinase_I PF01487.15 ORY56199.1 - 6.2e-34 118.2 0.0 3.1e-31 109.4 0.0 2.3 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 ORY56199.1 - 2.9e-26 92.5 0.0 4.6e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase AAA_16 PF13191.6 ORY56199.1 - 0.048 14.0 0.1 0.17 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.18 ORY56200.1 - 3.3e-07 29.6 0.1 1.5e-06 27.4 0.0 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY56200.1 - 0.00015 21.8 10.5 0.00022 21.2 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shikimate_dh_N PF08501.11 ORY56201.1 - 1.4e-21 76.5 0.0 2.9e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ORY56201.1 - 8.1e-10 38.3 1.0 1.5e-09 37.4 1.0 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 ORY56201.1 - 1.4e-05 25.2 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 ORY56201.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_dh_N PF08501.11 ORY56202.1 - 1.4e-09 38.0 0.0 2.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 ORY56202.1 - 0.04 14.0 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SpoU_methylase PF00588.19 ORY56202.1 - 0.16 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 SpoU rRNA Methylase family Dioxygenase_C PF00775.21 ORY56203.1 - 2e-45 154.4 0.0 3e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ORY56203.1 - 2.1e-33 114.0 0.0 3.8e-33 113.2 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ORY56203.1 - 0.00066 19.9 0.1 0.003 17.8 0.1 2.1 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fe-ADH PF00465.19 ORY56204.1 - 7.1e-71 238.9 7.2 8.3e-71 238.7 7.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORY56204.1 - 7.4e-08 32.4 3.6 1.4e-07 31.5 3.6 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Uso1_p115_head PF04869.14 ORY56205.1 - 1.9e-67 227.6 0.0 3.7e-67 226.7 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region zf-PARP PF00645.18 ORY56205.1 - 5.6e-24 84.8 0.1 2e-23 83.0 0.1 2.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Uso1_p115_C PF04871.13 ORY56205.1 - 1.5e-13 51.3 25.2 1.5e-13 51.3 25.2 3.7 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Arm_vescicular PF18770.1 ORY56205.1 - 8.1e-06 25.7 0.1 1.7e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Armadillo tether-repeat of vescicular transport factor Bromodomain PF00439.25 ORY56206.1 - 1.8e-17 63.2 0.1 6.7e-17 61.3 0.1 1.9 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 ORY56206.1 - 5.5e-05 23.1 0.0 0.00023 21.1 0.0 1.9 2 0 0 2 2 2 1 Bromodomain associated 2OG-FeII_Oxy_3 PF13640.6 ORY56207.1 - 9.4e-09 36.1 0.0 1.4e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_polI_A34 PF08208.11 ORY56428.1 - 5.7e-14 52.7 12.5 5.7e-14 52.7 12.5 2.4 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 RPN2_C PF18004.1 ORY56428.1 - 0.0089 16.0 4.0 0.0089 16.0 4.0 2.3 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain TFB6 PF17110.5 ORY56429.1 - 1.1e-06 28.5 0.0 6.9e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH F-box-like PF12937.7 ORY56430.1 - 3.6e-05 23.6 0.2 0.00014 21.7 0.2 1.9 1 0 0 1 1 1 1 F-box-like Hamartin PF04388.12 ORY56431.1 - 6.1 5.4 10.2 6.1 5.4 10.2 1.2 1 0 0 1 1 1 0 Hamartin protein IMS PF00817.20 ORY56432.1 - 8.9e-36 123.1 0.0 1.9e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 ORY56432.1 - 1.9e-20 73.0 4.0 3.9e-20 72.1 4.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 ORY56432.1 - 2.8e-12 47.4 0.0 8.9e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 ORY56432.1 - 7.7e-10 39.0 0.0 2.3e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY56432.1 - 3.2e-07 30.6 0.0 1e-06 29.0 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 ORY56432.1 - 4.1e-05 23.7 0.0 0.00028 21.0 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif LIG3_BRCT PF16759.5 ORY56432.1 - 0.0021 18.3 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 ORY56432.1 - 0.026 14.5 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Transposase_22 PF02994.14 ORY56432.1 - 0.066 13.4 0.5 24 5.2 0.0 2.9 3 0 0 3 3 3 0 L1 transposable element RBD-like domain Glyoxalase_4 PF13669.6 ORY56432.1 - 0.11 12.8 0.0 23 5.3 0.0 2.7 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sugar_tr PF00083.24 ORY56433.1 - 5.6e-88 295.8 17.7 6.6e-88 295.5 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY56433.1 - 9.9e-31 106.9 34.8 2.6e-30 105.5 23.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY56433.1 - 0.0042 15.6 0.9 0.0063 15.0 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3792 PF12670.7 ORY56433.1 - 0.38 10.9 17.1 0.42 10.8 5.5 3.4 2 2 0 2 2 2 0 Protein of unknown function (DUF3792) BT1 PF03092.16 ORY56433.1 - 0.52 8.5 5.0 0.37 9.0 1.4 2.1 2 0 0 2 2 2 0 BT1 family InaF-motif PF15018.6 ORY56433.1 - 9.3 6.2 7.6 1.3 9.0 1.3 2.9 2 0 0 2 2 2 0 TRP-interacting helix Mannosidase_ig PF17786.1 ORY56434.1 - 4.8e-17 62.3 0.9 1.9e-16 60.5 0.1 2.4 3 0 0 3 3 3 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 ORY56434.1 - 7e-09 36.3 0.0 2e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 ORY56434.1 - 1.1e-05 25.4 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 ORY56434.1 - 0.0023 17.6 0.0 0.0065 16.2 0.0 1.7 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_1 PF00232.18 ORY56435.1 - 2.5e-145 484.4 0.0 2.9e-145 484.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 GDP_Man_Dehyd PF16363.5 ORY56436.1 - 4.3e-57 194.0 0.0 4.1e-56 190.8 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY56436.1 - 2.1e-45 155.1 0.0 2.8e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY56436.1 - 5.3e-10 38.9 0.2 2.7e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 ORY56436.1 - 1.8e-08 33.7 0.0 2.7e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY56436.1 - 2.5e-07 30.1 0.0 3.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY56436.1 - 5.1e-06 25.8 0.2 0.00076 18.7 0.6 2.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein eIF3_subunit PF08597.10 ORY56437.1 - 1e-57 195.9 12.8 1.1e-57 195.7 12.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4407 PF14362.6 ORY56437.1 - 0.58 9.5 9.1 0.22 10.8 5.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YL1 PF05764.13 ORY56437.1 - 1.8 8.6 13.5 0.26 11.4 6.9 2.0 2 0 0 2 2 2 0 YL1 nuclear protein LRR_4 PF12799.7 ORY56438.1 - 0.2 12.1 1.4 19 5.9 0.1 3.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_S27e PF01667.17 ORY56439.1 - 3.9e-31 106.5 5.0 4.8e-31 106.2 5.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 ORY56439.1 - 0.032 14.6 1.3 0.19 12.2 0.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zf-CSL PF05207.13 ORY56439.1 - 0.21 11.3 3.1 0.43 10.4 3.1 1.6 1 1 0 1 1 1 0 CSL zinc finger F_bP_aldolase PF01116.20 ORY56440.1 - 2.4e-90 302.8 0.0 2.7e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Homeodomain PF00046.29 ORY56441.1 - 6.4e-18 64.4 0.8 6.9e-18 64.3 0.8 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY56441.1 - 8.7e-05 22.4 0.5 0.00012 21.8 0.0 1.5 2 0 0 2 2 2 1 Homeobox KN domain Mog1 PF04603.12 ORY56442.1 - 5.8e-38 130.4 0.0 7.1e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein F-box-like PF12937.7 ORY56443.1 - 1.6e-05 24.7 1.4 3.3e-05 23.7 1.4 1.6 1 0 0 1 1 1 1 F-box-like Brix PF04427.18 ORY56444.1 - 6.7e-36 124.2 0.0 9.7e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Brix domain tRNA-synt_1 PF00133.22 ORY56445.1 - 7.7e-130 434.0 0.0 1e-129 433.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY56445.1 - 1e-25 90.5 0.4 1.7e-25 89.7 0.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY56445.1 - 2.5e-17 62.7 0.0 8.8e-11 41.2 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORY56445.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ORY56445.1 - 0.11 11.8 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain zf-FPG_IleRS PF06827.14 ORY56445.1 - 0.7 9.8 4.0 1.4 8.8 4.0 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Anticodon_1 PF08264.13 ORY56446.1 - 8.9e-05 22.5 0.2 0.00013 21.9 0.2 1.3 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 ORY56446.1 - 0.7 9.8 7.6 2 8.4 7.6 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS YL1 PF05764.13 ORY56447.1 - 0.012 15.8 8.3 0.012 15.8 8.3 3.7 4 1 0 4 4 4 0 YL1 nuclear protein BSP_II PF05432.11 ORY56447.1 - 1.4 8.6 29.6 0.82 9.3 10.1 3.2 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 ORY56447.1 - 5.3 5.1 31.8 0.37 9.0 8.3 3.0 3 0 0 3 3 3 0 Nop14-like family RNase_PH PF01138.21 ORY56448.1 - 3.2e-21 76.2 0.0 5.2e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY56448.1 - 1.2e-12 47.7 0.0 2.8e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRM_1 PF00076.22 ORY56449.1 - 3.2e-33 113.4 0.0 2.3e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY56449.1 - 0.0047 17.0 0.0 0.014 15.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 ORY56449.1 - 0.0065 16.1 0.4 0.35 10.6 0.1 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain MFS_1 PF07690.16 ORY56450.1 - 5.1e-33 114.5 55.4 8.8e-26 90.7 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY56451.1 - 2.1e-32 112.4 56.3 1.2e-24 87.0 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY56451.1 - 0.00013 21.0 12.3 0.00013 21.0 12.3 3.2 2 2 1 3 3 3 1 Sugar (and other) transporter Aldo_ket_red PF00248.21 ORY56452.1 - 2.5e-38 132.0 0.0 3.1e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TetR_C_32 PF09209.11 ORY56452.1 - 0.031 14.3 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Exo_endo_phos PF03372.23 ORY56453.1 - 4.3e-08 33.0 0.0 7.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 ORY56453.1 - 0.15 13.0 3.2 0.21 12.5 0.5 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Peptidase_S8 PF00082.22 ORY56454.1 - 2.2e-36 125.6 2.0 3.4e-36 125.0 2.0 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY56454.1 - 2.2e-25 88.5 0.5 4.8e-25 87.4 0.5 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY56454.1 - 9.8e-06 26.3 0.9 0.027 15.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORY56454.1 - 0.025 15.1 0.2 1 9.8 0.0 2.6 3 0 0 3 3 3 0 N-terminal of Subtilase family DUF1970 PF09301.10 ORY56454.1 - 0.044 14.1 0.1 1.6 9.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) WD40 PF00400.32 ORY56455.1 - 1.4e-21 76.3 18.1 2.2e-07 31.4 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY56455.1 - 6.9e-05 23.1 0.0 0.17 12.2 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY56455.1 - 0.00029 19.9 0.2 0.018 14.0 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 ORY56455.1 - 0.064 12.0 0.0 0.29 9.8 0.0 2.0 2 0 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 ORY56455.1 - 0.077 11.6 0.2 1.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Zn_protease PF05618.11 ORY56455.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative ATP-dependant zinc protease Coatomer_WDAD PF04053.14 ORY56455.1 - 0.23 10.4 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Vps51 PF08700.11 ORY56457.1 - 8.9e-09 35.3 0.0 2.7e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 PHD PF00628.29 ORY56458.1 - 2.7e-16 59.2 19.8 3.3e-08 33.3 7.6 2.4 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 ORY56458.1 - 0.019 15.2 11.5 0.61 10.4 4.6 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORY56458.1 - 3.8 7.7 7.6 10 6.3 2.1 2.3 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD_2 PF13831.6 ORY56458.1 - 4.8 6.8 9.7 5 6.8 0.1 3.2 3 0 0 3 3 3 0 PHD-finger CKS PF01111.19 ORY56459.1 - 7.5e-16 58.2 0.6 1.6e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Peptidase_M16_M PF16187.5 ORY56460.1 - 9.3e-89 297.4 0.1 2.2e-88 296.2 0.1 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORY56460.1 - 2.2e-38 131.6 4.8 2.9e-36 124.7 0.1 3.4 2 1 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY56460.1 - 2.6e-30 105.8 0.1 2.3e-13 50.6 0.0 3.9 3 1 0 3 3 3 3 Peptidase M16 inactive domain DUF4476 PF14771.6 ORY56460.1 - 0.035 14.4 1.8 3.2 8.1 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) DUF1654 PF07867.11 ORY56529.1 - 0.043 13.6 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Fungal_trans PF04082.18 ORY56531.1 - 1.4e-14 53.8 0.0 1.9e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY56531.1 - 1.4e-05 25.1 4.3 2.3e-05 24.4 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aft1_HRA PF11786.8 ORY56532.1 - 1.2e-13 51.2 5.1 1.2e-13 51.2 5.1 4.3 4 2 0 4 4 4 1 Aft1 HRA domain bZIP_1 PF00170.21 ORY56532.1 - 1.7e-13 50.4 7.9 3.3e-13 49.5 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY56532.1 - 1.2e-06 28.5 4.4 1.2e-06 28.5 4.4 2.0 2 1 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.8 ORY56532.1 - 0.00014 22.2 0.3 0.00014 22.2 0.3 4.2 3 1 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain HALZ PF02183.18 ORY56532.1 - 0.012 15.9 0.2 0.02 15.1 0.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Macoilin PF09726.9 ORY56532.1 - 0.041 12.5 9.3 0.06 11.9 9.3 1.1 1 0 0 1 1 1 0 Macoilin family WD40_alt PF14077.6 ORY56532.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif ASD2 PF08687.11 ORY56532.1 - 0.69 9.4 10.0 1.1 8.8 10.0 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Prominin PF05478.11 ORY56532.1 - 0.84 7.5 1.7 1.1 7.2 1.7 1.0 1 0 0 1 1 1 0 Prominin PRP1_N PF06424.12 ORY56532.1 - 1.4 9.3 10.9 2.5 8.5 10.9 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Phlebovirus_NSM PF07246.11 ORY56532.1 - 1.7 7.9 4.0 2.5 7.4 4.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Nop53 PF07767.11 ORY56532.1 - 1.7 7.9 18.8 2.9 7.2 18.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Complex1_LYR PF05347.15 ORY56533.1 - 2.7e-11 43.4 3.0 4.2e-11 42.7 3.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY56533.1 - 0.054 14.3 1.0 0.083 13.6 1.0 1.4 1 1 0 1 1 1 0 Complex1_LYR-like IF4E PF01652.18 ORY56534.1 - 1.5e-26 93.1 0.0 2.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sigma70_r4_2 PF08281.12 ORY56534.1 - 0.37 10.5 1.5 0.63 9.8 0.3 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 FAD_binding_3 PF01494.19 ORY56536.1 - 1.3e-88 297.6 0.0 2.9e-87 293.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORY56536.1 - 5.8e-48 163.1 0.0 1.1e-47 162.2 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain NAD_binding_8 PF13450.6 ORY56536.1 - 0.0005 20.2 0.0 0.0015 18.7 0.0 1.9 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY56536.1 - 0.00057 18.7 0.0 0.00083 18.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 ORY56536.1 - 0.00095 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY56536.1 - 0.0014 17.9 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY56536.1 - 0.0023 17.2 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY56536.1 - 0.0096 15.2 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY56536.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 ORY56536.1 - 0.011 14.8 0.0 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.24 ORY56536.1 - 0.012 14.8 0.0 0.026 13.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 ORY56536.1 - 0.078 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 ORY56537.1 - 6.5e-25 86.9 10.5 8.6e-07 29.6 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 ORY56537.1 - 2.4e-21 75.8 2.5 4.7e-21 74.8 2.5 1.5 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 ORY56537.1 - 1.1e-05 25.6 0.0 0.56 10.6 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY56537.1 - 0.002 18.1 0.0 0.02 14.7 0.0 2.5 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A YopH_N PF09013.10 ORY56537.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 YopH, N-terminal Coatomer_WDAD PF04053.14 ORY56537.1 - 0.2 10.6 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region ATP_bind_1 PF03029.17 ORY56538.1 - 1.3e-49 169.1 0.3 8.9e-27 94.4 0.1 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein NUC153 PF08159.12 ORY56539.1 - 7.4e-13 48.1 1.4 1.7e-12 46.9 1.4 1.7 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 ORY56539.1 - 0.0086 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain TMEM208_SND2 PF05620.11 ORY56540.1 - 1.3e-43 148.6 2.0 2.6e-43 147.7 2.0 1.4 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 DUF2070 PF09843.9 ORY56540.1 - 0.74 8.0 3.4 0.92 7.7 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) E1-E2_ATPase PF00122.20 ORY56541.1 - 5.3e-39 133.6 0.7 5e-38 130.4 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY56541.1 - 2.5e-37 128.4 0.9 2.5e-37 128.4 0.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY56541.1 - 2.8e-20 73.5 0.6 1.3e-08 35.4 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY56541.1 - 2.4e-15 56.4 0.0 4.3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY56541.1 - 1.4e-10 40.7 0.0 3.1e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY56541.1 - 8.1e-05 22.5 0.5 0.00024 20.9 0.5 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sedlin_N PF04628.13 ORY56542.1 - 5.1e-37 126.9 0.0 2e-34 118.5 0.0 2.0 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.12 ORY56542.1 - 1.8e-08 34.4 0.0 2.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family zf_UBZ PF18439.1 ORY56543.1 - 0.11 12.1 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger DHO_dh PF01180.21 ORY56544.1 - 8.7e-20 71.1 0.0 1.7e-19 70.2 0.0 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 ORY56544.1 - 0.093 12.2 0.5 6.7 6.1 0.1 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein Peptidase_M28 PF04389.17 ORY56546.1 - 1.2e-25 90.3 0.0 1.9e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY56546.1 - 2.9e-08 33.7 0.0 4.3e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 L51_S25_CI-B8 PF05047.16 ORY56546.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1748 PF08520.10 ORY56547.1 - 4.7e-27 93.7 0.0 5.2e-27 93.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DAD PF02109.16 ORY56548.1 - 4.3e-45 152.5 1.1 5.4e-45 152.2 1.1 1.1 1 0 0 1 1 1 1 DAD family SURF6 PF04935.12 ORY56549.1 - 2.5e-39 135.1 44.7 2.5e-39 135.1 44.7 3.5 2 2 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 ORY56549.1 - 6.7e-12 45.8 9.5 6.7e-12 45.8 9.5 6.5 4 3 2 6 6 6 1 60S ribosome biogenesis protein Rrp14 Arf PF00025.21 ORY56550.1 - 8.8e-67 223.9 0.0 9.8e-67 223.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORY56550.1 - 2.9e-12 46.4 0.0 8.7e-09 35.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY56550.1 - 6e-10 38.8 0.0 7.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORY56550.1 - 1.9e-08 34.5 0.0 4.5e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY56550.1 - 9.2e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 ORY56550.1 - 1.9e-07 30.8 0.0 2.1e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY56550.1 - 5.1e-06 26.0 0.0 5.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 ORY56550.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation CENP-M PF11111.8 ORY56550.1 - 0.073 12.3 0.0 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Centromere protein M (CENP-M) ATP-synt_D PF01813.17 ORY56551.1 - 1.2e-73 247.1 0.5 1.6e-73 246.7 0.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit D F-box-like PF12937.7 ORY56553.1 - 0.13 12.1 0.9 0.41 10.6 0.1 2.4 2 1 0 2 2 2 0 F-box-like FH2 PF02181.23 ORY56554.1 - 6.3e-62 209.8 1.6 6.3e-62 209.8 1.6 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORY56554.1 - 5.5e-39 133.7 0.0 9.5e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORY56554.1 - 5.5e-26 91.4 0.1 1.4e-25 90.1 0.1 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Cep57_CLD_2 PF14197.6 ORY56554.1 - 0.0092 16.0 2.1 0.0092 16.0 2.1 2.8 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 Golgin_A5 PF09787.9 ORY56554.1 - 0.082 12.4 4.0 0.38 10.2 2.4 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Atg14 PF10186.9 ORY56554.1 - 1.2 8.2 4.2 2.8 6.9 4.2 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 ORY56554.1 - 2.2 6.1 3.8 13 3.6 0.0 2.1 2 0 0 2 2 2 0 Prominin Snapin_Pallidin PF14712.6 ORY56554.1 - 2.7 8.5 5.1 13 6.2 0.1 3.2 2 1 1 3 3 3 0 Snapin/Pallidin CASP_C PF08172.12 ORY56554.1 - 3.1 7.1 8.2 0.16 11.3 0.2 2.9 4 0 0 4 4 4 0 CASP C terminal Sugar_tr PF00083.24 ORY56555.1 - 2.7e-99 333.1 6.5 3e-99 332.9 6.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY56555.1 - 2.1e-31 109.2 36.2 2.9e-29 102.1 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY56555.1 - 0.00034 19.2 0.3 0.00034 19.2 0.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DASH_Dad4 PF08650.10 ORY56556.1 - 1.5e-24 85.8 0.3 1.6e-24 85.6 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.10 ORY56556.1 - 0.06 13.5 0.2 0.075 13.2 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 Alpha-L-AF_C PF06964.12 ORY56557.1 - 5.6e-26 91.7 0.0 9.7e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain VWA PF00092.28 ORY56557.1 - 7e-08 32.9 0.0 1.2e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY56557.1 - 0.00043 20.9 0.0 0.0018 18.9 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 ORY56557.1 - 0.047 13.8 0.1 0.084 13.0 0.1 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus VWA_3 PF13768.6 ORY56557.1 - 0.15 12.0 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain TPR_2 PF07719.17 ORY56557.1 - 0.4 10.9 1.3 5.2 7.4 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIA PF03153.13 ORY56557.1 - 2.9 7.8 10.3 4.3 7.2 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.27 ORY56558.1 - 1.4e-43 148.7 0.0 3.5e-43 147.4 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY56558.1 - 1.6e-17 63.8 0.0 4.8e-17 62.3 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain HBS1_N PF08938.10 ORY56558.1 - 1.9e-15 56.9 1.4 4.1e-15 55.9 1.4 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 ORY56558.1 - 3.2e-07 30.4 0.0 6.4e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORY56558.1 - 6.7e-06 26.4 0.1 1.4e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Arf PF00025.21 ORY56558.1 - 0.013 14.9 0.0 3.4 7.1 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family SRPRB PF09439.10 ORY56558.1 - 0.015 14.7 0.0 0.62 9.5 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 ORY56558.1 - 0.018 15.1 0.1 3.2 7.8 0.0 2.5 1 1 1 2 2 2 0 Dynamin family GTP_EFTU_D4 PF14578.6 ORY56558.1 - 0.03 14.2 1.0 0.24 11.3 0.1 2.3 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DLIC PF05783.11 ORY56558.1 - 0.55 9.0 4.0 2.4 6.9 0.0 2.6 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) SWI-SNF_Ssr4 PF08549.10 ORY56558.1 - 1.9 7.0 5.3 0.39 9.3 2.0 1.4 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1750) THOC2_N PF16134.5 ORY56559.1 - 1.9e-140 469.5 0.4 4.2e-140 468.4 0.4 1.6 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 ORY56559.1 - 3.4e-75 253.0 0.1 3.4e-75 253.0 0.1 2.5 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 ORY56559.1 - 2.6e-28 97.9 0.1 1.1e-27 95.9 0.0 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit ABC1 PF03109.16 ORY56562.1 - 1.3e-24 86.6 0.0 2.4e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family FAD_binding_3 PF01494.19 ORY56563.1 - 2.1e-19 70.0 0.1 3.1e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY56563.1 - 2.6e-07 30.6 6.4 0.0067 16.1 3.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY56563.1 - 6.8e-05 23.0 0.9 0.0002 21.5 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ORY56563.1 - 0.018 14.1 0.0 0.037 13.1 0.0 1.5 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 ORY56563.1 - 0.037 13.1 4.6 0.11 11.6 2.9 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 ORY56563.1 - 0.083 13.5 0.3 4.3 8.0 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY56563.1 - 0.11 11.7 0.1 6.9 5.8 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ORY56563.1 - 0.37 10.0 3.8 0.69 9.1 1.1 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY56563.1 - 0.42 9.2 2.2 12 4.5 1.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Phage_GP20 PF06810.11 ORY56564.1 - 0.46 10.3 5.5 0.74 9.6 5.5 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DMPK_coil PF08826.10 ORY56564.1 - 0.5 10.5 9.6 0.59 10.3 8.2 1.9 1 1 1 2 2 2 0 DMPK coiled coil domain like UPF0242 PF06785.11 ORY56564.1 - 1.5 8.9 6.4 2.1 8.4 6.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ATP11 PF06644.11 ORY56564.1 - 1.8 8.3 5.2 3.1 7.5 5.2 1.3 1 0 0 1 1 1 0 ATP11 protein FUSC PF04632.12 ORY56564.1 - 6.1 5.2 8.2 8.4 4.8 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Aldedh PF00171.22 ORY56785.1 - 5.1e-91 305.5 0.5 5.7e-91 305.3 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Helicase_C PF00271.31 ORY56786.1 - 2.6e-29 101.8 0.0 5e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY56786.1 - 3.5e-29 101.8 0.0 5.7e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase UTP25 PF06862.12 ORY56786.1 - 0.05 12.4 0.0 0.26 10.0 0.0 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 NPR3 PF03666.13 ORY56786.1 - 0.11 11.2 3.4 0.22 10.3 3.4 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TRAP_alpha PF03896.16 ORY56786.1 - 0.19 10.9 3.0 0.51 9.5 3.1 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Trypan_PARP PF05887.11 ORY56786.1 - 0.22 11.5 12.3 0.63 10.0 12.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF913 PF06025.12 ORY56786.1 - 0.54 9.2 1.9 0.99 8.3 1.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 ORY56786.1 - 2.6 7.4 11.9 5.7 6.3 11.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFB6 PF17110.5 ORY56786.1 - 5.7 6.6 6.2 18 5.0 2.0 2.5 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 ORY56786.1 - 9.1 4.4 6.8 18 3.5 6.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Red1 PF07964.11 ORY56786.1 - 9.8 4.3 10.6 16 3.6 10.6 1.2 1 0 0 1 1 1 0 Rec10 / Red1 TFR_dimer PF04253.15 ORY56787.1 - 1.8e-23 82.9 0.0 3.2e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 ORY56787.1 - 1e-15 57.9 0.1 2.2e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY56787.1 - 3.3e-10 39.9 0.7 1.9e-09 37.4 0.4 2.1 2 0 0 2 2 2 1 PA domain DUF16 PF01519.16 ORY56787.1 - 0.08 13.4 1.0 0.12 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Occludin_ELL PF07303.13 ORY56787.1 - 0.14 12.9 0.3 0.34 11.7 0.3 1.7 1 0 0 1 1 1 0 Occludin homology domain HAT_KAT11 PF08214.11 ORY56788.1 - 3.6e-40 138.3 0.0 5.4e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Histone acetylation protein K_channel_TID PF07941.11 ORY56788.1 - 0.21 12.0 10.0 0.14 12.6 5.5 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.19 ORY56788.1 - 0.23 12.0 17.3 1.3 9.7 10.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SH3_9 PF14604.6 ORY56789.1 - 2.1e-23 81.9 0.5 3.7e-13 49.1 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ORY56789.1 - 5.2e-18 64.4 0.0 6.6e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 ORY56789.1 - 1e-10 41.1 0.0 0.00066 19.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 ORY56789.1 - 7.1e-10 38.6 2.4 1.1e-09 38.1 2.4 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FCH PF00611.23 ORY56789.1 - 2.2e-06 27.9 0.4 5e-06 26.7 0.4 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_3 PF08239.11 ORY56789.1 - 0.0018 18.5 0.3 0.0044 17.3 0.3 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain C1_2 PF03107.16 ORY56789.1 - 0.032 14.6 0.6 0.054 13.8 0.6 1.3 1 0 0 1 1 1 0 C1 domain PHD PF00628.29 ORY56789.1 - 0.13 12.2 2.1 0.24 11.3 2.1 1.4 1 0 0 1 1 1 0 PHD-finger GRASP55_65 PF04495.14 ORY56790.1 - 4.1e-64 215.0 0.0 7.8e-51 172.0 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 ORY56790.1 - 8.3e-09 35.2 0.0 0.0024 17.7 0.0 2.5 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 ORY56790.1 - 5.6e-07 29.8 0.0 0.00017 21.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 ORY56790.1 - 0.22 11.9 0.0 14 6.1 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Pkinase PF00069.25 ORY56791.1 - 1.2e-57 195.3 0.0 1.6e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY56791.1 - 3e-43 148.0 0.0 4.1e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY56791.1 - 1.3e-06 27.5 0.0 2.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY56791.1 - 0.00043 19.7 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY56791.1 - 0.023 13.6 0.0 0.98 8.3 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY56791.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY56791.1 - 0.22 11.4 0.1 2.9 7.7 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family FAM72 PF14976.6 ORY56792.1 - 7.1e-06 26.2 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 FAM72 protein zf-MYND PF01753.18 ORY56793.1 - 5.3e-10 39.2 12.8 8.7e-10 38.5 12.8 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY56793.1 - 0.11 12.8 9.4 0.21 11.9 9.4 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORY56794.1 - 3e-09 36.8 17.8 5.2e-09 36.0 17.8 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY56794.1 - 0.00034 20.4 11.0 0.00055 19.7 11.0 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.24 ORY56794.1 - 0.019 15.1 5.8 0.04 14.1 5.8 1.5 1 0 0 1 1 1 0 B-box zinc finger PolC_DP2 PF03833.13 ORY56794.1 - 0.23 9.3 4.1 0.27 9.1 4.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PBP1_TM PF14812.6 ORY56795.1 - 0.00039 20.7 0.1 0.004 17.5 0.0 2.1 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal SpoIIIAH PF12685.7 ORY56795.1 - 0.012 15.5 5.2 0.012 15.5 5.2 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein NMN_transporter PF04973.12 ORY56795.1 - 0.044 13.7 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DUF1634 PF07843.11 ORY56795.1 - 0.092 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF4064 PF13273.6 ORY56795.1 - 0.11 12.7 0.3 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) CcmH PF03918.14 ORY56795.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF4366 PF14283.6 ORY56795.1 - 0.17 11.9 0.1 1.6 8.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Barwin PF00967.17 ORY56795.1 - 0.22 11.3 0.1 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Barwin family DPBB_1 PF03330.18 ORY56795.1 - 0.71 10.2 2.9 0.83 10.0 0.1 2.6 2 1 0 2 2 2 0 Lytic transglycolase AhpC-TSA_2 PF13911.6 ORY56796.1 - 1.3e-07 31.7 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ORY56796.1 - 3e-05 24.0 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY56796.1 - 0.00051 19.8 0.0 0.0033 17.2 0.0 1.9 2 0 0 2 2 2 1 Redoxin Ribonuc_red_sm PF00268.21 ORY56797.1 - 3.2e-120 400.8 1.2 3.9e-120 400.5 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SKN1 PF03935.15 ORY56798.1 - 5.1e-182 605.7 1.2 5.7e-182 605.6 1.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) AMP-binding PF00501.28 ORY56799.1 - 6.7e-88 295.1 0.1 9.4e-88 294.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SSF PF00474.17 ORY56800.1 - 3.7e-18 65.6 25.3 7.4e-18 64.6 25.3 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Amidase PF01425.21 ORY56801.1 - 1.4e-105 353.9 0.0 2.2e-105 353.2 0.0 1.3 1 1 0 1 1 1 1 Amidase CENP-S PF15630.6 ORY56801.1 - 0.16 12.4 0.2 0.33 11.4 0.2 1.4 1 0 0 1 1 1 0 CENP-S protein zf-MYND PF01753.18 ORY56802.1 - 0.042 14.0 3.0 0.064 13.4 3.0 1.3 1 0 0 1 1 1 0 MYND finger Fez1 PF06818.15 ORY56803.1 - 0.0015 19.0 1.3 0.0024 18.4 1.3 1.2 1 0 0 1 1 1 1 Fez1 Ilar_coat PF01787.16 ORY56803.1 - 0.022 14.6 1.6 0.037 13.8 1.6 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein ESM4 PF15952.5 ORY56803.1 - 0.038 14.4 1.1 0.062 13.7 1.1 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family DUF3847 PF12958.7 ORY56803.1 - 0.22 11.6 0.3 0.22 11.6 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3847) CENP-H PF05837.12 ORY56803.1 - 0.28 11.6 8.5 0.044 14.2 4.5 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SF1-HH PF16275.5 ORY56803.1 - 0.98 9.8 6.2 2.8 8.3 1.5 2.5 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain TMF_TATA_bd PF12325.8 ORY56803.1 - 1.5 9.1 8.4 0.33 11.2 5.2 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-Q PF13094.6 ORY56803.1 - 5.1 7.3 16.7 8.5 6.6 16.4 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Methyltransf_25 PF13649.6 ORY56804.1 - 0.0041 17.8 0.3 4.6 8.0 0.0 3.5 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORY56804.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF92 PF01940.16 ORY56805.1 - 1.2e-67 227.8 10.9 1.4e-67 227.6 10.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 ECH_1 PF00378.20 ORY56806.1 - 4.6e-21 75.3 0.0 5.6e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY56806.1 - 5.7e-09 35.9 0.0 7.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MoeA_N PF03453.17 ORY56806.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.5 2 0 0 2 2 2 0 MoeA N-terminal region (domain I and II) WD40 PF00400.32 ORY56807.1 - 6e-21 74.4 6.5 2.2e-05 25.1 0.1 6.3 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY56807.1 - 4.6e-12 46.1 0.0 0.017 15.4 0.0 4.8 2 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1373 PF07117.11 ORY56807.1 - 9.9e-05 22.4 0.4 0.00083 19.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1373) DUF5122 PF17164.4 ORY56807.1 - 0.065 13.5 1.5 8.7 6.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller CppA_N PF14506.6 ORY56807.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.4 1 1 0 1 1 1 0 CppA N-terminal Frtz PF11768.8 ORY56807.1 - 0.21 9.9 0.0 2.8 6.2 0.0 2.4 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz HD PF01966.22 ORY56809.1 - 7.9e-07 29.3 0.0 2.2e-06 27.9 0.0 1.8 1 1 1 2 2 2 1 HD domain HDOD PF08668.12 ORY56809.1 - 0.027 13.9 0.0 0.14 11.6 0.0 2.0 1 1 1 2 2 2 0 HDOD domain Aminotran_5 PF00266.19 ORY56810.1 - 1.3e-19 70.4 0.0 4.9e-19 68.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V GGACT PF06094.12 ORY56810.1 - 1.6e-16 61.0 0.0 3.6e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Aminotran_1_2 PF00155.21 ORY56810.1 - 1.2e-05 24.7 0.0 9.4e-05 21.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II B12D PF06522.11 ORY56811.1 - 2.2e-19 69.0 0.0 3.1e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit CAAD PF14159.6 ORY56811.1 - 0.12 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SUR7 PF06687.12 ORY56812.1 - 1.9e-21 76.7 15.2 2.5e-21 76.3 15.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.6 ORY56812.1 - 0.00021 21.1 10.6 0.00037 20.3 10.6 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction L_HMGIC_fpl PF10242.9 ORY56812.1 - 0.025 14.8 5.5 0.058 13.6 5.5 1.6 1 1 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein LRR19-TM PF15176.6 ORY56812.1 - 0.087 12.8 2.2 19 5.3 0.0 3.2 3 0 0 3 3 3 0 Leucine-rich repeat family 19 TM domain Transferase PF02458.15 ORY56812.1 - 0.16 10.6 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Transferase family Trp_oprn_chp PF09534.10 ORY56812.1 - 0.37 10.6 9.3 0.081 12.7 4.7 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 ORY56812.1 - 3.2 8.7 4.1 21 6.1 0.0 3.1 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain E1-E2_ATPase PF00122.20 ORY56812.1 - 4.4 6.8 9.4 0.072 12.6 1.8 1.9 2 1 0 2 2 2 0 E1-E2 ATPase DUF2062 PF09835.9 ORY56812.1 - 9.6 6.0 10.6 0.19 11.6 4.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) MFS_1 PF07690.16 ORY56813.1 - 6e-28 97.8 37.8 1e-27 97.0 37.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY56813.1 - 2.7e-13 49.6 9.2 2.7e-13 49.6 9.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ORY56813.1 - 0.78 8.0 4.9 0.96 7.6 0.4 2.6 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Thioredoxin PF00085.20 ORY56814.1 - 8.4e-27 93.2 0.0 1.4e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.12 ORY56814.1 - 2e-23 83.1 0.0 3.3e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 ORY56814.1 - 1.2e-06 28.9 0.0 2.7e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY56814.1 - 0.00011 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORY56814.1 - 0.011 16.1 0.0 0.12 12.7 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like DUF2332 PF10094.9 ORY56814.1 - 0.095 12.1 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2332) RRM_1 PF00076.22 ORY56815.1 - 3.6e-18 65.1 0.0 5.1e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY56815.1 - 0.00061 19.9 0.0 0.0015 18.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif LRR_1 PF00560.33 ORY56816.1 - 0.16 12.6 0.3 5.5 7.9 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.7 ORY56817.1 - 0.0026 17.6 0.8 0.0026 17.6 0.8 2.2 2 0 0 2 2 2 1 F-box-like Cation_efflux PF01545.21 ORY56818.1 - 2.4e-16 60.1 6.1 3e-16 59.7 6.1 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY56818.1 - 5.7e-08 32.8 0.6 1.2e-07 31.8 0.1 1.7 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Tail_VII PF17091.5 ORY56818.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.6 3 1 0 3 3 3 0 Inovirus G7P protein DUF4112 PF13430.6 ORY56819.1 - 8.9e-32 109.5 0.0 1.2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) UbiA PF01040.18 ORY56820.1 - 3.3e-53 180.6 15.8 5.3e-53 179.9 15.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosomal_L30 PF00327.20 ORY56821.1 - 1.6e-05 24.7 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RRM_1 PF00076.22 ORY56822.1 - 1.5e-10 40.7 0.0 2.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fmp27_WPPW PF10359.9 ORY56822.1 - 0.12 11.2 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Hamartin PF04388.12 ORY56822.1 - 0.88 8.2 4.0 1.1 7.9 4.0 1.1 1 0 0 1 1 1 0 Hamartin protein POT1PC PF16686.5 ORY56823.1 - 6.9e-16 58.5 0.0 8.7e-13 48.4 0.0 3.3 2 1 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 ORY56823.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 SRP-alpha_N PF04086.13 ORY56823.1 - 0.22 11.4 14.3 0.4 10.6 14.3 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC27 PF09507.10 ORY56823.1 - 7.9 5.7 20.1 13 5.1 20.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HSBP1 PF06825.12 ORY56825.1 - 9.4e-17 60.6 1.4 1.2e-16 60.2 1.4 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 ORY56825.1 - 0.042 13.9 0.1 0.054 13.5 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PRR18 PF15671.5 ORY56825.1 - 0.082 12.8 9.3 0.11 12.3 9.3 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 Cyanate_lyase PF02560.14 ORY56827.1 - 6.6e-30 102.8 0.1 1.1e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 ORY56827.1 - 6.1e-07 29.7 0.0 1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 ORY56827.1 - 3.5e-05 23.8 0.0 0.00015 21.8 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix Sigma70_r4 PF04545.16 ORY56827.1 - 0.026 14.0 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.12 ORY56827.1 - 0.093 12.7 0.0 8.5 6.4 0.0 2.4 2 0 0 2 2 2 0 HTH domain DUF1376 PF07120.11 ORY56827.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1376) Homeodomain PF00046.29 ORY56827.1 - 0.16 11.8 0.0 0.53 10.2 0.0 1.8 1 1 1 2 2 2 0 Homeodomain HTH_38 PF13936.6 ORY56827.1 - 0.24 11.2 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Golgin_A5 PF09787.9 ORY56828.1 - 0.0039 16.7 4.6 0.0039 16.7 4.6 2.6 3 0 0 3 3 3 2 Golgin subfamily A member 5 AIP3 PF03915.13 ORY56828.1 - 0.044 12.9 4.4 0.058 12.5 1.0 2.1 2 0 0 2 2 2 0 Actin interacting protein 3 KxDL PF10241.9 ORY56828.1 - 0.74 10.1 8.5 3 8.2 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein YlqD PF11068.8 ORY56828.1 - 1.9 8.9 12.4 0.46 10.9 1.9 2.3 2 0 0 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.12 ORY56828.1 - 6.3 6.9 25.9 3.3 7.8 4.9 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 ORY56828.1 - 7.2 6.9 18.3 0.46 10.7 4.7 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding FH2 PF02181.23 ORY56828.1 - 9.1 5.3 7.7 0.81 8.7 0.8 2.0 2 0 0 2 2 2 0 Formin Homology 2 Domain GCP_N_terminal PF17681.1 ORY57090.1 - 3.6e-13 49.8 0.0 6.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY57090.1 - 2.8e-10 40.2 0.0 5.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal RNA_pol_Rpb1_5 PF04998.17 ORY57091.1 - 6.3e-93 311.1 0.0 6.6e-92 307.7 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY57091.1 - 1e-64 217.8 0.5 8.2e-64 214.8 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY57091.1 - 9.1e-34 116.7 0.0 1.9e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 ORY57091.1 - 3e-28 99.1 3.0 2e-23 83.2 0.0 4.0 3 1 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 ORY57091.1 - 4.2e-23 81.4 0.0 1.8e-22 79.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 YhfH PF14149.6 ORY57091.1 - 0.022 14.7 0.2 0.051 13.6 0.2 1.6 1 0 0 1 1 1 0 YhfH-like protein SDA1 PF05285.12 ORY57091.1 - 4 6.8 36.4 0.31 10.4 3.2 2.4 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 ORY57091.1 - 7.5 5.8 39.5 0.55 9.5 21.1 2.3 2 0 0 2 2 2 0 BUD22 Wbp11 PF09429.10 ORY57092.1 - 5.7e-18 65.1 10.1 1.1e-17 64.2 10.1 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.7 ORY57092.1 - 2.1e-16 60.4 8.6 2.1e-16 60.4 8.6 5.5 4 1 0 4 4 4 1 mRNA biogenesis factor 14-3-3 PF00244.20 ORY57092.1 - 0.95 8.9 3.6 1.5 8.3 3.6 1.3 1 0 0 1 1 1 0 14-3-3 protein DUF4810 PF16068.5 ORY57092.1 - 9.2 6.9 5.8 27 5.4 0.2 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4810) Dus PF01207.17 ORY57095.1 - 1.5e-45 155.6 0.0 2.7e-44 151.5 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DFRP_C PF16543.5 ORY57096.1 - 6.8e-25 87.4 1.5 6.8e-25 87.4 1.5 3.9 4 1 1 5 5 5 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 ORY57096.1 - 3e-05 23.8 5.3 3.4e-05 23.6 1.7 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY57096.1 - 0.00074 19.3 8.4 0.0032 17.2 2.5 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 ORY57096.1 - 0.00091 19.9 14.1 0.0015 19.2 4.2 3.8 2 1 1 3 3 3 1 Torus domain zf_CCCH_4 PF18345.1 ORY57096.1 - 0.001 19.1 8.3 0.001 19.1 8.3 2.8 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 ORY57096.1 - 0.0025 18.0 0.5 0.19 12.0 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger containing family SPT16 PF08644.11 ORY57096.1 - 6.5 6.9 14.6 0.14 12.4 1.3 3.1 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) zf-CCCH_2 PF14608.6 ORY57096.1 - 8.4 7.0 9.6 11 6.6 3.8 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger BAH PF01426.18 ORY57097.1 - 0.029 14.2 0.0 0.041 13.7 0.0 1.2 1 0 0 1 1 1 0 BAH domain O-FucT PF10250.9 ORY57099.1 - 1.1e-07 31.9 0.0 1.1e-06 28.7 0.0 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 ORY57100.1 - 0.012 15.3 0.0 1.7 8.3 0.0 3.0 2 1 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase TetR_C_15 PF17918.1 ORY57100.1 - 0.035 14.8 0.0 0.38 11.5 0.0 2.3 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TruB_C_2 PF16198.5 ORY57102.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain GDA1_CD39 PF01150.17 ORY57104.1 - 3.3e-108 362.1 0.0 4.5e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family A_deaminase PF00962.22 ORY57105.1 - 8.8e-20 71.3 0.0 1.1e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 ORY57105.1 - 0.038 13.3 0.0 1.3 8.2 0.0 2.5 2 1 0 2 2 2 0 Amidohydrolase family UcrQ PF02939.16 ORY57106.1 - 1.7e-28 98.4 1.0 1.9e-28 98.2 1.0 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 ORY57106.1 - 0.002 18.5 0.0 0.0021 18.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Cyt-b5 PF00173.28 ORY57107.1 - 8.3e-16 57.9 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 ORY57108.1 - 0.0018 18.1 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like Metallophos PF00149.28 ORY57109.1 - 3.2e-36 125.8 0.8 4.7e-36 125.2 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY57109.1 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ORY57109.1 - 0.028 14.0 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF2407_C PF13373.6 ORY57110.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Hrs_helical PF12210.8 ORY57110.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate IF-2B PF01008.17 ORY57111.1 - 6.8e-56 189.5 0.0 1.5e-55 188.4 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family Pkinase PF00069.25 ORY57112.1 - 9.6e-39 133.3 0.0 1.3e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY57112.1 - 3.4e-26 92.1 0.0 4.7e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY57112.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY57112.1 - 0.28 10.1 0.0 0.43 9.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SUIM_assoc PF16619.5 ORY57112.1 - 1.2 9.2 7.9 7 6.8 7.9 2.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 F-box-like PF12937.7 ORY57113.1 - 0.00039 20.3 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like Nitr_red_bet_C PF14711.6 ORY57113.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal TetR_C_24 PF17932.1 ORY57114.1 - 0.024 14.9 0.0 0.029 14.6 0.0 1.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Beach PF02138.18 ORY57115.1 - 5.6e-118 393.3 0.0 8.1e-118 392.8 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 ORY57115.1 - 3.8e-13 49.4 0.0 8.8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 ORY57115.1 - 6.3e-09 36.3 6.7 0.0013 19.5 0.4 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 ORY57115.1 - 4.2e-06 27.0 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily FYVE PF01363.21 ORY57115.1 - 0.00029 20.9 5.1 0.00059 19.9 5.1 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 ORY57115.1 - 0.72 10.1 2.7 1.8 8.8 2.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Cohesin_load PF10345.9 ORY57118.1 - 2.9e-10 39.2 0.0 4.7e-06 25.3 0.0 2.5 2 1 0 2 2 2 2 Cohesin loading factor TPR_MalT PF17874.1 ORY57118.1 - 0.00063 19.2 4.4 0.2 11.0 0.4 3.7 4 0 0 4 4 4 2 MalT-like TPR region TPR_2 PF07719.17 ORY57118.1 - 0.0045 17.0 1.1 0.89 9.8 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY57118.1 - 0.0082 16.4 6.8 1.6 9.1 0.4 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY57118.1 - 0.079 13.0 0.0 2.3 8.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY57118.1 - 0.15 13.0 3.8 17 6.6 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SOBP PF15279.6 ORY57120.1 - 1.2 9.7 18.3 1.4 9.4 18.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GATA PF00320.27 ORY57121.1 - 1e-24 85.9 18.5 5.4e-16 57.9 2.3 2.1 2 0 0 2 2 2 2 GATA zinc finger ZF-HD_dimer PF04770.12 ORY57121.1 - 0.09 13.1 0.2 0.09 13.1 0.2 2.5 2 1 0 2 2 2 0 ZF-HD protein dimerisation region Zn-ribbon_8 PF09723.10 ORY57121.1 - 0.15 12.2 8.8 0.25 11.5 0.3 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORY57121.1 - 0.16 12.2 10.0 1.3 9.3 2.7 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 ORY57121.1 - 0.29 11.0 9.3 2.6 8.0 0.2 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ORY57121.1 - 0.75 9.4 10.0 1.3 8.6 1.1 2.7 2 1 0 2 2 2 0 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.15 ORY57121.1 - 1.2 9.2 8.2 13 5.9 4.1 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zinc_ribbon_9 PF14369.6 ORY57121.1 - 2.9 8.2 11.9 4.8 7.5 3.8 2.9 2 1 0 2 2 2 0 zinc-ribbon TetR_C_24 PF17932.1 ORY57123.1 - 0.0001 22.5 0.2 2.3 8.5 0.0 3.3 3 0 0 3 3 3 3 Tetracyclin repressor-like, C-terminal domain DUF3106 PF11304.8 ORY57123.1 - 0.014 15.9 0.3 2.8 8.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) F-box-like PF12937.7 ORY57126.1 - 0.0028 17.5 0.0 0.007 16.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like TraP PF07296.11 ORY57126.1 - 0.044 13.0 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 TraP protein Apolipoprotein PF01442.18 ORY57128.1 - 0.0019 18.1 13.4 1.3 8.9 8.4 3.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF1741 PF08427.10 ORY57128.1 - 0.047 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) ETF_alpha PF00766.19 ORY57128.1 - 0.068 13.2 0.4 2.5 8.2 0.0 3.5 2 1 2 4 4 4 0 Electron transfer flavoprotein FAD-binding domain Toprim_Crpt PF13342.6 ORY57128.1 - 0.34 10.9 0.2 0.34 10.9 0.2 2.5 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase ApoLp-III PF07464.11 ORY57128.1 - 0.34 11.0 0.1 0.34 11.0 0.1 4.4 1 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF2894 PF11445.8 ORY57128.1 - 0.48 10.9 7.3 33 4.9 0.6 4.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2894) TMP_2 PF06791.13 ORY57128.1 - 0.91 9.2 11.5 0.22 11.2 0.6 3.5 2 2 0 3 3 3 0 Prophage tail length tape measure protein Mt_ATP-synt_B PF05405.14 ORY57128.1 - 3.6 7.2 11.3 7.2 6.2 1.7 3.6 4 0 0 4 4 4 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Pkinase PF00069.25 ORY57390.1 - 7.7e-11 41.9 0.0 9.1e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY57390.1 - 0.041 13.2 0.0 0.048 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_transf_22 PF03901.17 ORY57391.1 - 1.4e-69 235.3 6.4 2.8e-69 234.4 6.4 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF382 PF04037.13 ORY57394.1 - 4.2e-59 198.2 1.8 4.2e-59 198.2 1.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 ORY57394.1 - 1.8e-18 66.1 5.0 4.7e-18 64.8 5.0 1.8 1 0 0 1 1 1 1 PSP RTC PF01137.21 ORY57395.1 - 6.2e-46 156.4 0.0 7.2e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 ORY57395.1 - 2.1e-33 114.9 0.0 3.2e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain UQ_con PF00179.26 ORY57396.1 - 1.7e-40 137.9 0.0 2e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 ORY57396.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 ORY57396.1 - 0.099 12.9 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 RWD domain MitMem_reg PF13012.6 ORY57397.1 - 6.3e-36 123.2 0.1 1.2e-35 122.3 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY57397.1 - 2.5e-30 104.9 0.1 5.5e-30 103.8 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CobT PF06213.12 ORY57397.1 - 0.039 13.3 8.2 0.063 12.7 8.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Connexin PF00029.19 ORY57397.1 - 0.17 11.6 0.2 0.28 10.9 0.2 1.3 1 0 0 1 1 1 0 Connexin Choline_transpo PF04515.12 ORY57398.1 - 5.1e-44 150.8 6.9 5.1e-44 150.8 6.9 1.6 2 0 0 2 2 2 1 Plasma-membrane choline transporter MFS_Mycoplasma PF07672.13 ORY57398.1 - 0.13 11.5 2.0 0.32 10.2 2.0 1.6 1 0 0 1 1 1 0 Mycoplasma MFS transporter PUF PF00806.19 ORY57399.1 - 8.5e-15 53.5 0.0 1.8e-05 24.2 0.0 6.3 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Not1 PF04054.15 ORY57400.1 - 3.2e-120 401.4 0.3 6.5e-120 400.4 0.3 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 ORY57400.1 - 6.3e-100 333.2 2.4 2.7e-98 327.8 0.7 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 ORY57400.1 - 8.3e-57 191.2 0.5 2e-56 190.0 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 ORY57400.1 - 3.6e-53 179.6 0.0 8.5e-53 178.4 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 ORY57400.1 - 3e-43 147.5 0.1 7.9e-43 146.1 0.1 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Cas1_AcylT PF07779.12 ORY57401.1 - 6.3e-118 394.7 13.9 7.9e-118 394.4 13.9 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 ORY57401.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p EptA_B_N PF08019.12 ORY57401.1 - 3 7.7 10.2 1.8 8.5 1.7 3.2 2 1 1 3 3 3 0 Phosphoethanolamine transferase EptA/EptB CIA30 PF08547.12 ORY57403.1 - 6.7e-24 84.7 0.0 8.3e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Cyclin_N PF00134.23 ORY57404.1 - 5.3e-10 39.1 0.0 1.4e-09 37.8 0.0 1.7 2 1 0 2 2 2 1 Cyclin, N-terminal domain GST_N_3 PF13417.6 ORY57405.1 - 5.3e-09 36.4 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY57405.1 - 0.00016 21.6 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY57405.1 - 0.022 15.1 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY57405.1 - 0.038 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain NmrA PF05368.13 ORY57406.1 - 3.4e-58 197.0 0.0 4.1e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY57406.1 - 9.6e-17 61.5 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY57406.1 - 3.5e-07 29.5 0.0 5.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY57406.1 - 7.2e-07 28.9 0.0 1.5e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORY57406.1 - 1.4e-05 25.4 0.0 2.7e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 ORY57406.1 - 9.3e-05 22.8 0.5 0.00028 21.3 0.1 2.0 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 ORY57406.1 - 0.0022 17.9 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 ORY57406.1 - 0.0081 16.7 0.1 0.017 15.7 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 ORY57406.1 - 0.009 16.3 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.25 ORY57406.1 - 0.057 12.9 0.0 0.44 10.0 0.0 2.2 3 0 0 3 3 3 0 short chain dehydrogenase YbjQ_1 PF01906.17 ORY57407.1 - 1.1e-05 26.0 0.0 0.0011 19.6 0.0 2.0 2 0 0 2 2 2 2 Putative heavy-metal-binding WGG PF10273.9 ORY57408.1 - 1.9e-18 66.9 0.1 3.4e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 ORY57408.1 - 0.31 11.2 1.3 0.73 10.0 1.3 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain HpcH_HpaI PF03328.14 ORY57409.1 - 7.7e-36 123.3 0.0 1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.6 ORY57409.1 - 0.03 13.8 0.7 5.8 6.3 0.1 2.9 3 0 0 3 3 3 0 Phosphoenolpyruvate phosphomutase NAD_binding_7 PF13241.6 ORY57410.1 - 8.3e-29 100.1 0.0 1.4e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORY57410.1 - 1.6e-20 72.5 1.7 2.5e-20 71.9 1.7 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORY57410.1 - 1e-13 50.5 0.7 2.9e-13 49.0 0.7 1.9 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Ribosomal_L14 PF00238.19 ORY57411.1 - 7.4e-44 148.8 3.2 8.3e-44 148.6 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cellulase PF00150.18 ORY57412.1 - 1.2e-15 57.7 0.0 1.8e-11 44.0 0.0 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY57412.1 - 8.3e-15 55.1 0.0 1.6e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain zf-CHY PF05495.12 ORY57413.1 - 5.2e-14 52.5 13.2 1.1e-13 51.5 13.2 1.5 1 1 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 ORY57413.1 - 0.0072 16.2 8.9 0.26 11.2 0.1 3.2 2 1 1 3 3 3 2 RNA polymerases M/15 Kd subunit zf_UBZ PF18439.1 ORY57413.1 - 0.0094 15.5 5.6 7.2 6.3 0.1 3.3 3 0 0 3 3 3 3 Ubiquitin-Binding Zinc Finger Cys_rich_KTR PF14205.6 ORY57413.1 - 0.02 14.7 5.1 1.2 9.0 0.1 2.4 1 1 1 2 2 2 0 Cysteine-rich KTR HypA PF01155.19 ORY57413.1 - 0.35 10.9 9.5 1.7 8.7 9.5 1.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 ORY57413.1 - 0.5 10.7 8.1 0.32 11.3 4.4 2.5 1 1 1 2 2 2 0 zinc-ribbon DpnI PF06044.12 ORY57413.1 - 1.8 8.2 7.2 3.2 7.3 0.2 2.0 1 1 1 2 2 2 0 Dam-replacing family Evr1_Alr PF04777.13 ORY57413.1 - 4.4 7.8 10.1 1.4e+02 3.0 10.1 2.7 1 1 0 1 1 1 0 Erv1 / Alr family 3Beta_HSD PF01073.19 ORY57414.1 - 1.1e-55 188.6 0.0 3e-50 170.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY57414.1 - 5.5e-27 94.8 0.0 7.4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY57414.1 - 8.7e-13 48.4 0.1 9.2e-10 38.4 0.2 2.5 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY57414.1 - 2e-10 40.3 0.2 1.9e-08 33.8 0.1 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 ORY57414.1 - 6e-10 38.7 0.0 9e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY57414.1 - 4.7e-09 36.4 0.1 6.8e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY57414.1 - 1.9e-05 24.0 0.6 0.00019 20.7 1.1 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein ABM PF03992.16 ORY57416.1 - 1.6e-08 34.5 0.0 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Dabb PF07876.12 ORY57416.1 - 0.012 16.2 0.0 0.014 16.0 0.0 1.1 1 0 0 1 1 1 0 Stress responsive A/B Barrel Domain LSM PF01423.22 ORY57417.1 - 1.3e-12 47.2 0.0 1.5e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY57417.1 - 0.0046 17.1 0.1 0.0083 16.2 0.1 1.4 1 1 0 1 1 1 1 Ataxin 2 SM domain Dabb PF07876.12 ORY57673.1 - 4.3e-10 40.1 0.0 4.6e-10 40.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Zn_clus PF00172.18 ORY57675.1 - 6e-05 23.1 9.7 0.0001 22.3 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY57675.1 - 0.046 12.8 0.2 0.083 11.9 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain ALG3 PF05208.13 ORY57676.1 - 5.8e-133 443.7 15.4 6.8e-133 443.5 15.4 1.0 1 0 0 1 1 1 1 ALG3 protein PMT_2 PF13231.6 ORY57676.1 - 0.0086 16.3 16.2 0.023 14.9 16.2 1.8 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase CHAD PF05235.14 ORY57677.1 - 0.024 14.6 2.3 0.041 13.9 2.3 1.3 1 0 0 1 1 1 0 CHAD domain Hydrolase_4 PF12146.8 ORY57678.1 - 3.7e-06 26.4 0.0 5.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORY57678.1 - 1.1e-05 25.3 0.1 1.7e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY57678.1 - 0.0005 20.7 1.1 0.0005 20.7 1.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY57678.1 - 0.026 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 ORY57678.1 - 0.044 13.7 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 Cutinase LIP PF03583.14 ORY57678.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Secretory lipase DUF1749 PF08538.10 ORY57678.1 - 0.27 10.3 0.0 0.38 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) GFO_IDH_MocA PF01408.22 ORY57679.1 - 2.8e-15 57.2 0.0 4.8e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY57679.1 - 8.7e-09 35.4 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 ORY57679.1 - 0.033 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain SOBP PF15279.6 ORY57680.1 - 0.72 10.4 8.5 0.84 10.2 8.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Glyco_hydro_12 PF01670.16 ORY57683.1 - 2.6e-46 158.3 13.6 2.6e-46 158.3 13.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 CBM_1 PF00734.18 ORY57683.1 - 0.00012 22.0 4.8 0.00063 19.6 4.8 2.3 1 0 0 1 1 1 1 Fungal cellulose binding domain Bax1-I PF01027.20 ORY57684.1 - 4.3e-31 108.4 12.5 5.9e-31 107.9 12.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 NmrA PF05368.13 ORY57685.1 - 6.9e-37 127.2 0.0 8.1e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY57685.1 - 7.1e-13 48.9 0.2 9.6e-13 48.4 0.2 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY57685.1 - 0.00026 20.1 0.0 0.00034 19.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY57685.1 - 0.00084 18.9 0.1 0.0022 17.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY57685.1 - 0.059 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TetR_C_21 PF17926.1 ORY57685.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Carn_acyltransf PF00755.20 ORY57686.1 - 5.3e-201 669.3 0.0 6.2e-201 669.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase PLAC8 PF04749.17 ORY57687.1 - 5.9e-17 62.5 18.1 7.3e-17 62.2 18.1 1.1 1 0 0 1 1 1 1 PLAC8 family Sugar_tr PF00083.24 ORY57689.1 - 2e-101 340.1 24.5 2.3e-101 339.9 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY57689.1 - 1.9e-19 69.8 45.7 3.4e-17 62.4 22.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_3 PF07859.13 ORY57690.1 - 8e-15 55.3 0.1 1.4e-14 54.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY57690.1 - 2.1e-10 40.1 1.5 1.7e-09 37.1 1.7 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ORY57690.1 - 0.0003 21.5 0.7 0.0003 21.5 0.7 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 ORY57690.1 - 0.074 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Cupin_2 PF07883.11 ORY57691.1 - 1.6e-15 56.6 0.0 1.6e-14 53.3 0.0 2.3 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 ORY57691.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain FAD_binding_3 PF01494.19 ORY57692.1 - 1.6e-09 37.5 0.1 1.3e-05 24.7 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 ORY57692.1 - 0.032 14.5 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ADH_zinc_N PF00107.26 ORY57693.1 - 9.4e-23 80.6 0.1 1.8e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY57693.1 - 2.2e-10 40.4 0.1 5.5e-10 39.1 0.1 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY57693.1 - 7e-09 36.8 0.0 1.4e-08 35.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LAL_C2 PF18603.1 ORY57693.1 - 0.0027 17.8 0.6 0.0027 17.8 0.6 2.3 2 1 1 3 3 3 1 L-amino acid ligase C-terminal domain 2 PA PF02225.22 ORY57693.1 - 0.0053 16.8 0.2 0.023 14.7 0.2 2.2 1 1 0 1 1 1 1 PA domain ADH_N_2 PF16884.5 ORY57693.1 - 0.0086 16.0 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 ORY57693.1 - 0.047 13.2 0.5 0.089 12.2 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ARID PF01388.21 ORY57694.1 - 5.1e-10 39.9 0.0 1.1e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain HAD_2 PF13419.6 ORY57695.1 - 7.7e-08 32.6 0.0 1.7e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY57695.1 - 5.2e-05 23.6 0.0 0.00014 22.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY57695.1 - 0.00013 21.9 0.0 0.00028 20.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Med26 PF08711.11 ORY57696.1 - 5.1e-12 45.6 0.0 2.6e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Fungal_trans PF04082.18 ORY57697.1 - 4e-26 91.6 0.0 5.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY57697.1 - 2.6e-05 24.3 8.2 4.6e-05 23.5 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4385 PF14328.6 ORY57698.1 - 5e-60 201.8 0.1 6.2e-60 201.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4385) zf-C2H2_jaz PF12171.8 ORY57699.1 - 1.3e-16 60.4 27.3 2e-06 27.9 0.1 6.7 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY57699.1 - 2e-09 37.5 32.4 0.75 10.8 0.2 8.1 8 1 0 8 8 8 5 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY57699.1 - 2.2e-06 27.8 37.9 0.18 12.3 0.9 8.0 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-met PF12874.7 ORY57699.1 - 0.0015 18.9 34.6 0.89 10.0 0.8 6.9 7 0 0 7 7 7 4 Zinc-finger of C2H2 type CK_II_beta PF01214.18 ORY57699.1 - 0.0028 17.5 0.1 0.0028 17.5 0.1 2.6 1 1 2 3 3 3 1 Casein kinase II regulatory subunit zf-C2H2_aberr PF17017.5 ORY57699.1 - 0.0063 16.7 0.1 0.019 15.1 0.1 1.8 1 0 0 1 1 1 1 Aberrant zinc-finger zinc_ribbon_12 PF11331.8 ORY57699.1 - 0.083 12.7 0.6 0.083 12.7 0.6 2.6 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-LYAR PF08790.11 ORY57699.1 - 0.29 11.1 0.1 0.29 11.1 0.1 5.6 5 1 1 6 6 6 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 ORY57699.1 - 0.36 11.2 20.8 1.8 8.9 0.0 4.0 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.6 ORY57699.1 - 1.4 8.9 23.6 1.2 9.1 3.9 5.5 3 1 2 5 5 5 0 Probable zinc-ribbon domain zf-C2H2_jaz PF12171.8 ORY57700.1 - 1.6e-17 63.3 27.9 1.4e-06 28.4 0.2 6.9 5 2 2 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY57700.1 - 5.8e-08 32.9 33.1 0.024 15.0 0.1 6.3 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY57700.1 - 9.6e-05 22.9 36.3 0.94 10.5 1.6 8.1 8 1 0 8 8 8 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY57700.1 - 0.00075 19.8 40.5 0.3 11.6 2.0 8.0 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY57700.1 - 0.054 13.5 0.1 0.054 13.5 0.1 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger DUF4187 PF13821.6 ORY57700.1 - 0.058 13.2 0.1 0.058 13.2 0.1 3.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4187) CK_II_beta PF01214.18 ORY57700.1 - 0.13 12.1 10.2 0.12 12.2 0.5 3.2 2 1 2 4 4 4 0 Casein kinase II regulatory subunit zf_PR_Knuckle PF18445.1 ORY57700.1 - 0.96 9.3 6.3 1.7 8.5 0.1 2.8 3 0 0 3 3 3 0 PR zinc knuckle motif zf-C2H2_2 PF12756.7 ORY57700.1 - 1.2 9.6 24.1 6.3 7.2 0.0 3.9 2 2 2 4 4 4 0 C2H2 type zinc-finger (2 copies) NAD_binding_2 PF03446.15 ORY57701.1 - 4.4e-33 114.7 3.5 2.7e-32 112.1 3.5 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY57701.1 - 6.3e-27 94.2 0.0 1.1e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORY57701.1 - 0.026 15.1 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lipase_GDSL PF00657.22 ORY57702.1 - 2e-11 44.3 0.1 2.8e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY57702.1 - 5.6e-07 30.1 1.2 9.3e-07 29.4 1.2 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MCM PF00493.23 ORY57703.1 - 3e-97 324.1 0.0 4.6e-97 323.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY57703.1 - 4.2e-38 130.0 0.2 7e-38 129.3 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY57703.1 - 5.5e-27 94.0 1.1 1.4e-26 92.8 1.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY57703.1 - 1.1e-12 48.5 2.8 7.4e-12 45.8 0.4 2.7 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.14 ORY57703.1 - 8.9e-09 35.5 0.0 2.7e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY57703.1 - 2e-07 30.6 0.0 0.00014 21.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY57703.1 - 0.00051 19.9 0.0 0.006 16.5 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY57703.1 - 0.00056 19.6 0.2 0.94 9.2 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 ORY57703.1 - 0.012 16.0 1.1 0.056 13.8 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain FAD_binding_3 PF01494.19 ORY57704.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain VirB3 PF05101.13 ORY57704.1 - 0.44 10.8 7.9 0.14 12.4 3.2 2.2 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Cellulase PF00150.18 ORY57706.1 - 0.052 13.0 0.0 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Rieske PF00355.26 ORY57708.1 - 1.1e-10 41.3 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 ORY57708.1 - 1.2e-08 35.3 1.8 1.2e-08 35.3 1.8 1.9 2 1 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region DUF1353 PF07087.11 ORY57708.1 - 0.15 11.8 0.0 7.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Got1 PF04178.12 ORY57709.1 - 3.1e-26 92.0 16.3 4.6e-26 91.5 16.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family OAD_gamma PF04277.13 ORY57709.1 - 1 10.0 16.8 2.3 8.8 0.0 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain SdpI PF13630.6 ORY57709.1 - 2.5 8.3 16.7 6.3 7.0 3.6 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF3685 PF12452.8 ORY57709.1 - 4.5 6.9 5.6 6.2 6.5 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) Img2 PF05046.14 ORY57710.1 - 6e-21 74.5 0.0 7.9e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUZ PF12752.7 ORY57711.1 - 4e-12 46.7 1.9 4e-12 46.7 1.9 8.4 7 3 0 7 7 7 1 SUZ domain R3H PF01424.22 ORY57711.1 - 7.9e-07 29.0 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain bZIP_2 PF07716.15 ORY57714.1 - 5.4e-11 42.4 13.2 2.5e-10 40.3 13.2 1.9 1 1 1 2 2 2 2 Basic region leucine zipper Shugoshin_N PF07558.11 ORY57714.1 - 7.4e-05 22.5 0.4 0.00019 21.2 0.4 1.8 1 1 0 1 1 1 1 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 ORY57714.1 - 0.00034 20.9 1.0 0.00065 20.0 0.6 1.7 1 1 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.21 ORY57714.1 - 0.003 17.6 13.5 0.0088 16.1 13.5 1.8 1 1 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 ORY57714.1 - 0.018 15.7 3.0 0.021 15.4 2.7 1.4 1 1 0 1 1 1 0 Initiation control protein YabA bZIP_Maf PF03131.17 ORY57714.1 - 0.028 14.9 7.9 0.034 14.7 7.9 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF2203 PF09969.9 ORY57714.1 - 0.028 15.1 1.8 0.034 14.8 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) GIT_CC PF16559.5 ORY57714.1 - 0.033 14.1 4.2 0.051 13.5 4.2 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF5094 PF17015.5 ORY57714.1 - 0.044 13.9 2.2 0.051 13.7 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) ZapB PF06005.12 ORY57714.1 - 0.61 10.6 10.5 0.17 12.4 6.8 1.8 1 1 1 2 2 2 0 Cell division protein ZapB SET PF00856.28 ORY57715.1 - 2.9e-11 44.0 0.0 1.4e-10 41.8 0.0 2.1 2 1 0 2 2 2 1 SET domain GMC_oxred_N PF00732.19 ORY57716.1 - 3.2e-55 187.6 0.0 4.1e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY57716.1 - 3.7e-32 111.8 0.0 7.3e-32 110.9 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY57716.1 - 0.0021 18.2 0.1 0.0051 17.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY57716.1 - 0.0026 16.9 0.2 0.0038 16.3 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY57716.1 - 0.014 14.7 0.1 0.023 14.0 0.1 1.2 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 ORY57716.1 - 0.13 11.8 0.3 0.3 10.6 0.3 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ras PF00071.22 ORY57718.1 - 5.2e-63 211.5 1.9 6.1e-63 211.3 1.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY57718.1 - 3.7e-36 124.0 1.0 5.8e-36 123.4 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY57718.1 - 9.8e-18 64.2 0.2 1.3e-17 63.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY57718.1 - 2.8e-05 23.6 0.1 3.4e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY57718.1 - 3.4e-05 23.9 0.0 6.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY57718.1 - 4.3e-05 23.1 0.8 8.4e-05 22.2 0.4 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY57718.1 - 5.8e-05 22.6 0.2 7.8e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORY57718.1 - 0.00012 22.0 1.5 0.13 12.1 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY57718.1 - 0.011 16.1 0.0 0.016 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 ORY57718.1 - 0.016 15.0 0.3 0.036 13.9 0.1 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 ORY57718.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 ORY57718.1 - 0.022 14.2 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA PF00004.29 ORY57718.1 - 0.028 14.9 0.2 0.52 10.7 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY57718.1 - 0.048 13.9 0.0 0.084 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY57718.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 ORY57718.1 - 0.056 12.7 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 ORY57718.1 - 0.057 12.9 0.2 0.21 11.1 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 ORY57718.1 - 0.067 12.7 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 ORY57718.1 - 0.12 12.9 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter DUF3873 PF12989.7 ORY57718.1 - 0.14 12.6 0.1 0.23 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Zn_clus PF00172.18 ORY57977.1 - 7e-05 22.9 6.7 0.00012 22.2 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY57979.1 - 1.7e-27 96.3 36.3 2.4e-27 95.8 36.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_68 PF02435.16 ORY57979.1 - 0.22 10.3 0.0 0.32 9.8 0.0 1.1 1 0 0 1 1 1 0 Levansucrase/Invertase eIF-3c_N PF05470.12 ORY57980.1 - 2.8e-178 594.0 17.8 1.5e-176 588.2 17.8 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 ORY57980.1 - 1e-14 54.9 1.2 5.7e-14 52.5 0.0 2.7 3 0 0 3 3 3 1 PCI domain YqaH PF17448.2 ORY57980.1 - 0.041 14.2 0.1 4 7.8 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized YqaH-like OSCP PF00213.18 ORY57981.1 - 5.4e-27 95.0 9.5 1.2e-15 58.0 1.6 2.1 1 1 1 2 2 2 2 ATP synthase delta (OSCP) subunit AA_permease_2 PF13520.6 ORY57983.1 - 6.1e-64 216.4 45.2 7.6e-64 216.1 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY57983.1 - 7.4e-23 80.9 40.4 1e-22 80.4 40.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.22 ORY57984.1 - 3.5e-176 586.3 0.0 3.9e-176 586.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Rpr2 PF04032.16 ORY57985.1 - 2.8e-23 82.0 0.0 1.1e-22 80.1 0.0 2.0 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Mut7-C PF01927.16 ORY57985.1 - 0.062 13.4 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain WD40 PF00400.32 ORY57986.1 - 8e-62 203.7 28.8 2.2e-08 34.6 0.2 11.9 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 ORY57986.1 - 4.4e-48 162.8 0.4 7.8e-48 162.0 0.4 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 ORY57986.1 - 2.7e-14 53.2 3.9 0.41 11.0 0.2 7.7 5 2 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY57986.1 - 3.2e-07 29.6 3.6 0.00076 18.5 0.0 4.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY57986.1 - 1.6e-06 27.7 0.0 0.00013 21.5 0.0 3.2 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 ORY57986.1 - 0.00033 19.4 12.4 0.011 14.4 1.4 5.4 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Kelch_2 PF07646.15 ORY57986.1 - 0.00095 19.1 0.1 0.59 10.2 0.1 3.3 3 0 0 3 3 3 1 Kelch motif PCI PF01399.27 ORY57988.1 - 1.8e-10 41.3 0.0 3.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain DIMCO_N PF16844.5 ORY57988.1 - 0.0023 18.2 0.1 0.0069 16.7 0.1 1.8 1 0 0 1 1 1 1 Dinitrogenase iron-molybdenum cofactor, N-terminal COX7C PF02935.16 ORY57989.1 - 1.7e-10 41.0 1.7 3.2e-10 40.1 1.1 1.8 2 0 0 2 2 2 1 Cytochrome c oxidase subunit VIIc Med12 PF09497.10 ORY57990.1 - 2.4e-21 75.8 0.5 6.5e-21 74.4 0.5 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 ORY57990.1 - 0.15 10.9 0.0 1.9 7.2 0.0 2.4 1 1 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain ANT PF03374.14 ORY57990.1 - 0.2 12.0 0.1 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Phage antirepressor protein KilAC domain TetR_C_6 PF13977.6 ORY57990.1 - 5.5 7.3 8.7 2.2 8.5 2.0 3.3 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal Asp PF00026.23 ORY57991.1 - 7.7e-74 248.9 3.6 1.4e-73 248.1 3.6 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY57991.1 - 2.5e-11 44.1 3.3 1.9e-08 34.7 0.4 3.8 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY57991.1 - 9e-05 23.0 1.5 0.079 13.6 0.0 3.0 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY57991.1 - 0.056 14.0 0.0 1.3 9.7 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Kinesin PF00225.23 ORY57993.1 - 2.2e-112 375.3 0.1 7.5e-112 373.5 0.1 2.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY57993.1 - 4.9e-26 91.4 0.0 1.5e-25 89.9 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding DUF2087 PF09860.9 ORY57993.1 - 0.047 13.8 0.3 1.2 9.3 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) zf-RING_2 PF13639.6 ORY57994.1 - 1.4e-05 25.3 10.6 3.6e-05 24.0 6.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORY57994.1 - 5.7e-05 23.3 5.1 5.7e-05 23.3 5.1 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORY57994.1 - 0.00041 20.0 3.5 0.014 15.1 0.4 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY57994.1 - 0.0018 18.1 4.5 0.016 15.0 4.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY57994.1 - 0.0048 16.7 5.5 0.0048 16.7 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF1677 PF07911.13 ORY57994.1 - 0.085 13.3 0.4 2.1 8.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) zf-ANAPC11 PF12861.7 ORY57994.1 - 0.21 11.7 2.9 0.48 10.5 2.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY57994.1 - 2.6 8.3 6.6 3.2 8.0 3.6 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORY57994.1 - 2.8 7.9 5.9 1.5 8.7 2.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY57994.1 - 3.8 7.6 7.1 4.4 7.4 4.0 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY57994.1 - 3.8 7.5 7.8 2.1 8.3 4.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY57994.1 - 4.4 7.4 7.2 19 5.4 4.3 2.5 2 0 0 2 2 2 0 RING-type zinc-finger PHD PF00628.29 ORY57994.1 - 8.2 6.4 7.7 28 4.7 0.1 2.4 2 0 0 2 2 2 0 PHD-finger adh_short PF00106.25 ORY57995.1 - 1.5e-21 76.7 0.0 2.2e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY57995.1 - 1.8e-15 57.2 0.0 2.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY57995.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY57995.1 - 0.0012 18.7 0.1 0.0028 17.6 0.1 1.9 1 1 0 1 1 1 1 NAD(P)H-binding GST_C_3 PF14497.6 ORY57996.1 - 1.7e-16 60.2 0.0 3.1e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY57996.1 - 2.8e-07 30.8 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY57996.1 - 5.4e-05 23.1 0.0 0.00022 21.2 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY57996.1 - 0.00046 20.9 0.0 0.00092 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 ORY57996.1 - 0.00049 20.3 0.0 0.0033 17.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY57996.1 - 0.0025 18.2 0.0 0.0049 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY57996.1 - 0.091 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EI24 PF07264.11 ORY57997.1 - 1.4e-13 51.5 2.9 1.9e-13 51.1 2.9 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Redoxin PF08534.10 ORY57998.1 - 3e-33 114.6 0.0 3.3e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY57998.1 - 5.4e-10 39.2 0.0 6.5e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family SNARE_assoc PF09335.11 ORY57999.1 - 3.7e-07 30.6 1.1 3.8e-07 30.6 1.1 1.0 1 0 0 1 1 1 1 SNARE associated Golgi protein Topoisom_I PF01028.20 ORY58000.1 - 1.1e-96 322.6 2.8 1.1e-96 322.6 2.8 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 ORY58000.1 - 1.8e-94 315.2 0.2 1.8e-94 315.2 0.2 3.9 3 2 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 ORY58000.1 - 1.9e-26 91.8 0.1 1.1e-25 89.3 0.1 2.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain NDUF_B12 PF08122.12 ORY58001.1 - 5.5e-20 71.2 0.5 5.9e-20 71.1 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ESSS PF10183.9 ORY58001.1 - 0.75 10.0 7.1 0.44 10.8 0.4 2.1 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4123 PF13503.6 ORY58003.1 - 0.11 13.0 0.1 0.31 11.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4123) PUF PF00806.19 ORY58003.1 - 0.11 12.2 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat Glyoxalase PF00903.25 ORY58005.1 - 2.2e-20 73.1 0.1 2.5e-20 72.9 0.1 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY58005.1 - 1.1e-05 25.6 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORY58005.1 - 0.00014 22.6 0.0 0.00036 21.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ORY58005.1 - 0.0087 16.2 0.0 0.0099 16.0 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Abhydrolase_1 PF00561.20 ORY58006.1 - 1.1e-21 77.7 1.0 1.3e-19 70.9 1.0 2.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY58006.1 - 1.4e-16 60.4 0.0 2.7e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S28 PF05577.12 ORY58006.1 - 0.058 12.2 0.1 0.087 11.6 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 SNARE_assoc PF09335.11 ORY58007.1 - 3.1e-18 66.4 13.3 5.5e-18 65.6 8.5 2.6 3 0 0 3 3 3 1 SNARE associated Golgi protein TctB PF07331.11 ORY58007.1 - 0.013 15.8 3.7 0.013 15.8 3.7 2.4 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family zf-MYND PF01753.18 ORY58008.1 - 8e-11 41.9 6.5 1.5e-10 41.0 6.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY58008.1 - 0.13 12.6 7.7 0.9 9.9 7.9 2.1 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zinc_ribbon_12 PF11331.8 ORY58008.1 - 0.76 9.6 6.2 0.18 11.7 1.6 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain zf-MYND PF01753.18 ORY58009.1 - 3.3e-06 27.1 14.1 5.4e-06 26.4 14.1 1.4 1 0 0 1 1 1 1 MYND finger IcmF-related PF06761.12 ORY58009.1 - 0.0023 17.5 0.1 0.0035 16.9 0.1 1.2 1 0 0 1 1 1 1 Intracellular multiplication and human macrophage-killing zf-MYND PF01753.18 ORY58011.1 - 3.3e-09 36.7 9.7 7.3e-09 35.6 9.7 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY58011.1 - 4.4 7.7 9.7 4.4 7.7 8.4 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Tim17 PF02466.19 ORY58013.1 - 0.0027 18.1 0.2 0.23 11.9 0.1 3.0 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family IPK PF03770.16 ORY58014.1 - 1.4e-40 139.3 0.0 1e-24 87.5 0.0 2.1 2 0 0 2 2 2 2 Inositol polyphosphate kinase CHRD PF07452.12 ORY58015.1 - 5.3e-14 53.2 0.1 7.3e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 CHRD domain DUF3678 PF12435.8 ORY58016.1 - 0.075 12.4 0.6 0.16 11.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) F-box PF00646.33 ORY58018.1 - 0.0011 18.8 0.4 0.012 15.5 0.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY58018.1 - 0.0059 16.5 0.3 0.017 15.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like PUF PF00806.19 ORY58019.1 - 1.7e-51 169.1 8.0 2.1e-06 27.1 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PTR2 PF00854.21 ORY58329.1 - 6.6e-84 282.0 5.2 8.9e-84 281.6 5.2 1.2 1 0 0 1 1 1 1 POT family Abhydrolase_1 PF00561.20 ORY58330.1 - 2.2e-06 27.5 0.0 0.00036 20.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY58330.1 - 8.5e-06 26.5 1.7 1.4e-05 25.9 1.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORY58330.1 - 0.021 14.9 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein DLH PF01738.18 ORY58330.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family ubiquitin PF00240.23 ORY58331.1 - 1.8e-10 40.4 0.0 2.2e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY58331.1 - 9.7e-06 25.3 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY58331.1 - 0.031 14.7 0.0 0.035 14.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain DnaJ_C PF01556.18 ORY58333.1 - 3.4e-38 131.1 0.0 4.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY58333.1 - 1.3e-23 82.9 2.5 2e-23 82.3 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY58333.1 - 5e-10 39.6 17.4 9.8e-10 38.7 17.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY58333.1 - 0.0054 16.7 14.1 0.0058 16.6 3.3 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORY58333.1 - 8.3 6.5 8.3 10 6.2 0.4 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Oxidored_FMN PF00724.20 ORY58334.1 - 1e-69 235.4 0.0 1.6e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1611_N PF17396.2 ORY58334.1 - 0.16 12.2 0.1 4.2 7.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain G3P_antiterm PF04309.12 ORY58334.1 - 0.21 11.0 0.1 0.5 9.8 0.0 1.6 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator XG_FTase PF03254.13 ORY58335.1 - 2.9e-05 22.9 0.0 0.0022 16.7 0.0 2.1 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase PIG-L PF02585.17 ORY58336.1 - 4.3e-13 50.0 0.0 2.2e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 GlcNAc-PI de-N-acetylase F5_F8_type_C PF00754.25 ORY58336.1 - 1.1e-05 25.5 3.3 0.0016 18.6 1.1 2.4 2 0 0 2 2 2 2 F5/8 type C domain PapC_C PF13953.6 ORY58336.1 - 0.061 13.1 0.0 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 PapC C-terminal domain SWI2_SNF2 PF18766.1 ORY58336.1 - 0.079 12.6 0.1 6.6 6.3 0.1 2.9 3 0 0 3 3 3 0 SWI2/SNF2 ATPase Acetyltransf_3 PF13302.7 ORY58337.1 - 2e-15 57.7 1.5 1e-14 55.4 1.5 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY58337.1 - 1.3e-06 28.6 0.0 2.5e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ORY58337.1 - 0.00017 21.3 0.1 0.0022 17.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY58337.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 FR47-like protein CBS PF00571.28 ORY58338.1 - 1.3e-31 108.8 6.7 4.8e-08 33.3 0.1 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 ORY58338.1 - 4.7e-07 29.7 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 PB1 domain Colicin PF01024.19 ORY58338.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Colicin pore forming domain DUF2380 PF09533.10 ORY58338.1 - 0.0029 17.3 0.1 0.0086 15.7 0.1 1.8 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) NAD_binding_10 PF13460.6 ORY58338.1 - 0.62 9.9 7.2 0.26 11.1 1.8 2.3 2 0 0 2 2 2 0 NAD(P)H-binding DUF4530 PF15039.6 ORY58338.1 - 1.5 9.0 4.7 6.4 7.0 4.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) BTB PF00651.31 ORY58339.1 - 8.9e-10 38.8 0.0 1.1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain ATG22 PF11700.8 ORY58340.1 - 3.5e-135 451.3 25.1 4e-135 451.1 25.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF2678 PF10856.8 ORY58340.1 - 0.0017 18.3 7.5 0.021 14.7 5.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2678) Ctr PF04145.15 ORY58340.1 - 0.37 11.4 5.5 1.2 9.7 2.9 2.6 2 0 0 2 2 2 0 Ctr copper transporter family Translin PF01997.16 ORY58341.1 - 4.2e-43 147.7 0.0 5.8e-42 144.0 0.0 2.0 1 1 0 1 1 1 1 Translin family CCDC24 PF15669.5 ORY58341.1 - 0.0022 17.9 0.1 0.0032 17.4 0.1 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Epimerase_2 PF02350.19 ORY58341.1 - 0.05 12.5 0.1 0.14 11.0 0.2 1.6 2 0 0 2 2 2 0 UDP-N-acetylglucosamine 2-epimerase Spectrin PF00435.21 ORY58341.1 - 0.14 12.6 0.8 0.39 11.2 0.3 2.0 2 1 0 2 2 2 0 Spectrin repeat PhyH PF05721.13 ORY58342.1 - 3.4e-15 56.9 0.0 4.4e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) COesterase PF00135.28 ORY58343.1 - 3.1e-80 270.5 0.0 4.2e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY58343.1 - 4.7e-07 29.9 0.2 2.7e-06 27.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold NTP_transf_9 PF04248.12 ORY58344.1 - 2.1e-29 101.2 0.4 2.4e-29 101.1 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) RGS PF00615.19 ORY58345.1 - 9.8e-07 29.1 0.0 8.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Helo_like_N PF17111.5 ORY58347.1 - 0.081 12.3 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Tmemb_cc2 PF10267.9 ORY58347.1 - 0.48 9.5 2.0 9.6 5.2 0.1 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein BNR_4 PF15892.5 ORY58348.1 - 5.6e-70 235.8 0.0 7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 BNR repeat-containing family member Sugar_tr PF00083.24 ORY58349.1 - 6.4e-70 236.2 23.3 7.8e-70 236.0 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY58349.1 - 2.5e-14 53.0 26.5 2.5e-14 53.0 26.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY58349.1 - 1.7e-05 23.5 3.4 3e-05 22.7 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AAA PF00004.29 ORY58350.1 - 4.3e-12 46.6 0.0 1e-11 45.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY58350.1 - 3.8e-06 27.0 0.0 4.2e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 ORY58350.1 - 3e-05 24.3 0.0 0.00017 21.9 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 ORY58350.1 - 3.2e-05 23.7 0.0 8.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY58350.1 - 3.4e-05 24.0 0.0 0.00012 22.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORY58350.1 - 5e-05 23.3 0.0 0.00013 22.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORY58350.1 - 0.00014 21.9 0.0 0.00032 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY58350.1 - 0.0006 19.4 0.0 0.0014 18.1 0.0 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 ORY58350.1 - 0.0011 19.4 0.0 0.0094 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_assoc_2 PF16193.5 ORY58350.1 - 0.0018 18.6 0.1 0.0092 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 ORY58350.1 - 0.0028 17.5 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.6 ORY58350.1 - 0.0042 16.8 0.1 0.085 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORY58350.1 - 0.0048 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 ORY58350.1 - 0.012 15.2 0.1 0.035 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY58350.1 - 0.013 16.1 0.0 0.032 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY58350.1 - 0.018 14.9 0.5 0.044 13.7 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase RNA_helicase PF00910.22 ORY58350.1 - 0.033 14.6 0.1 0.14 12.5 0.0 2.0 1 1 1 2 2 2 0 RNA helicase AAA_17 PF13207.6 ORY58350.1 - 0.045 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORY58350.1 - 0.059 13.4 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ORY58350.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY58350.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY58350.1 - 0.073 13.6 0.1 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Methyltr_RsmB-F PF01189.17 ORY58350.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F ATPase PF06745.13 ORY58350.1 - 0.14 11.5 0.0 1.3 8.3 0.0 2.1 1 1 1 2 2 2 0 KaiC Mid2 PF04478.12 ORY58352.1 - 0.0035 17.2 0.5 0.0052 16.6 0.5 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MGC-24 PF05283.11 ORY58352.1 - 0.074 13.5 2.1 0.12 12.8 2.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SSP160 PF06933.11 ORY58352.1 - 0.98 7.5 14.5 1.3 7.1 14.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Synaptobrevin PF00957.21 ORY58353.1 - 1.1e-15 57.2 0.4 2.3e-15 56.1 0.4 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY58353.1 - 4.2e-12 45.9 0.0 8.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec1 PF00995.23 ORY58354.1 - 1.8e-120 403.9 0.0 2e-120 403.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Flavin_Reduct PF01613.18 ORY58357.1 - 2e-15 57.2 0.0 3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Putative_PNPOx PF01243.20 ORY58357.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Cu_amine_oxid PF01179.20 ORY58358.1 - 1.1e-125 419.8 3.9 1.7e-125 419.2 3.9 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 ORY58358.1 - 3.2e-25 87.7 0.6 8.4e-25 86.3 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 ORY58358.1 - 1.9e-07 31.2 0.0 3.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 ORY58360.1 - 7.4e-59 199.7 0.2 1.3e-58 198.9 0.2 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 ORY58360.1 - 2.3e-25 88.2 0.6 4.8e-25 87.1 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 ORY58360.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxid PF01179.20 ORY58362.1 - 6.4e-34 117.6 0.0 7.3e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Myb_DNA-binding PF00249.31 ORY58363.1 - 3.8e-24 84.6 14.5 6.8e-11 42.2 0.0 4.6 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY58363.1 - 1.2e-22 79.9 9.0 9.1e-10 38.6 0.0 4.3 4 0 0 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY58363.1 - 0.0025 17.8 0.0 0.035 14.2 0.0 3.1 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 ORY58363.1 - 0.01 16.0 0.0 4.2 7.6 0.0 3.9 3 0 0 3 3 3 0 Rap1 Myb domain SLIDE PF09111.10 ORY58363.1 - 0.78 9.8 0.0 0.78 9.8 0.0 3.9 4 1 1 5 5 5 0 SLIDE zf-C3HC4 PF00097.25 ORY58368.1 - 5.4e-06 26.2 11.2 3.8e-05 23.5 8.4 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.18 ORY58368.1 - 1.8e-05 25.3 2.5 1.8e-05 25.3 2.5 4.2 2 1 1 3 3 3 1 TRAF-type zinc finger zf-RING_2 PF13639.6 ORY58368.1 - 8.3e-05 22.8 8.3 8.3e-05 22.8 8.3 3.1 3 1 0 3 3 3 1 Ring finger domain Sina PF03145.16 ORY58368.1 - 0.00022 21.3 17.4 0.00043 20.3 1.8 3.4 1 1 2 3 3 3 2 Seven in absentia protein family zf-RING_UBOX PF13445.6 ORY58368.1 - 0.0018 18.3 5.9 0.0018 18.3 5.9 2.1 2 0 0 2 2 2 1 RING-type zinc-finger Rootletin PF15035.6 ORY58368.1 - 0.0024 17.9 0.1 0.0031 17.6 0.1 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 ORY58368.1 - 0.0037 17.1 0.6 0.0059 16.5 0.6 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH zf-C3HC4_2 PF13923.6 ORY58368.1 - 0.0064 16.3 12.3 0.01 15.6 8.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) HALZ PF02183.18 ORY58368.1 - 0.016 15.4 2.5 0.036 14.3 2.5 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper zf-ANAPC11 PF12861.7 ORY58368.1 - 0.016 15.2 6.8 0.016 15.2 6.8 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger ZapB PF06005.12 ORY58368.1 - 0.026 15.0 2.1 0.056 13.9 2.1 1.6 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 ORY58368.1 - 0.028 14.2 1.8 0.054 13.3 1.8 1.4 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 ORY58368.1 - 0.052 13.7 2.3 0.11 12.6 2.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor ADIP PF11559.8 ORY58368.1 - 0.14 12.2 2.7 0.22 11.6 2.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding zf-C3HC4_4 PF15227.6 ORY58368.1 - 1.3 9.2 11.7 0.21 11.8 7.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Cupin_8 PF13621.6 ORY58370.1 - 5.8e-10 39.3 0.1 6.3e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORY58370.1 - 0.00075 19.1 0.0 0.0008 19.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 ORY58370.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 ORY58370.1 - 0.018 15.4 0.0 0.021 15.3 0.0 1.2 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_6 PF12852.7 ORY58370.1 - 0.07 12.8 0.0 0.081 12.6 0.0 1.1 1 0 0 1 1 1 0 Cupin Leader_Trp PF08255.11 ORY58370.1 - 0.16 12.0 0.2 0.16 12.0 0.2 2.1 2 0 0 2 2 2 0 Trp-operon Leader Peptide Cupin_1 PF00190.22 ORY58370.1 - 0.18 11.4 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Cupin MerC PF03203.14 ORY58371.1 - 0.0099 16.3 6.3 0.0099 16.3 6.3 2.6 2 1 0 2 2 2 1 MerC mercury resistance protein Astro_capsid_N PF03115.14 ORY58371.1 - 0.22 10.2 0.1 0.31 9.7 0.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor ASC PF00858.24 ORY58371.1 - 0.56 9.1 1.2 1 8.3 1.2 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel G_path_suppress PF15991.5 ORY58654.1 - 0.014 15.5 0.1 0.014 15.5 0.1 2.0 1 1 0 2 2 2 0 G-protein pathway suppressor Ribosomal_S30 PF04758.14 ORY58655.1 - 5.4e-22 77.8 7.1 6.2e-22 77.5 7.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 zf-CCCH PF00642.24 ORY58656.1 - 0.0043 16.9 0.8 0.0043 16.9 0.8 4.0 3 1 1 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY58656.1 - 1.2 9.3 21.0 0.73 10.0 1.6 4.5 4 1 1 5 5 5 0 Zinc finger domain Lustrin_cystein PF14625.6 ORY58656.1 - 3.6 8.0 13.1 5.4 7.5 0.1 3.8 3 1 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Sybindin PF04099.12 ORY58657.1 - 1.7e-42 144.7 0.0 1.9e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORY58657.1 - 2.1e-09 37.6 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Radical_SAM_C PF16199.5 ORY58658.1 - 1.3e-32 111.6 0.0 3.7e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 ORY58658.1 - 4.7e-19 69.4 0.1 2.2e-18 67.2 0.0 2.1 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 ORY58658.1 - 1.2e-10 41.7 0.1 2.1e-10 40.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY58658.1 - 6.8e-07 29.3 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY58658.1 - 0.0034 17.8 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tudor_3 PF18115.1 ORY58659.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 ORY58659.1 - 0.0011 19.3 0.0 0.064 13.6 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 ORY58659.1 - 0.0014 18.7 0.0 0.054 13.6 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 ORY58659.1 - 0.053 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 ORY58659.1 - 0.19 12.1 0.0 8.6 6.9 0.0 2.5 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain GST_N_3 PF13417.6 ORY58660.1 - 2.8e-11 43.7 0.0 4.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY58660.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin2_C PF04399.13 ORY58660.1 - 0.17 11.8 0.1 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain HABP4_PAI-RBP1 PF04774.15 ORY58661.1 - 0.35 11.7 3.8 0.84 10.5 3.8 1.6 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family SAPS PF04499.15 ORY58662.1 - 8e-94 315.1 0.0 1.3e-93 314.4 0.0 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein FAA_hydrolase PF01557.18 ORY58663.1 - 1.1e-55 188.7 0.0 1.4e-55 188.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 ORY58663.1 - 0.00023 20.9 0.7 0.0006 19.6 0.0 2.0 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 ORY58663.1 - 0.051 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 KH domain FBPase PF00316.20 ORY58664.1 - 5.9e-72 241.1 0.1 7.6e-72 240.8 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 ORY58664.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family PUL PF08324.11 ORY58665.1 - 2e-50 171.6 8.4 2.6e-50 171.2 8.4 1.1 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 ORY58665.1 - 5.1e-41 139.5 0.3 9.9e-41 138.5 0.3 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 ORY58665.1 - 2.3e-34 116.8 14.1 3.1e-05 24.7 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY58665.1 - 0.0048 17.2 0.1 21 5.5 0.0 4.8 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 ORY58666.1 - 3.6e-81 272.9 0.0 4.6e-81 272.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY58666.1 - 7.3e-14 52.5 0.5 1.6e-13 51.4 0.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YdaS_antitoxin PF15943.5 ORY58666.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT FYVE PF01363.21 ORY58668.1 - 1.4e-20 73.2 0.1 2.3e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.8 ORY58668.1 - 1.4e-13 50.3 1.9 2.9e-13 49.3 1.9 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-RING_2 PF13639.6 ORY58668.1 - 7.6 7.0 7.2 9.4 6.7 4.4 2.2 2 0 0 2 2 2 0 Ring finger domain DAO PF01266.24 ORY58669.1 - 1.5e-31 110.3 1.0 1.9e-31 110.0 1.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY58669.1 - 7.1e-06 25.5 0.1 3.1e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY58669.1 - 1.5e-05 25.5 0.4 9.5e-05 22.9 1.0 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY58669.1 - 4.4e-05 22.7 0.1 5.9e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 ORY58669.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ORY58669.1 - 0.00027 21.3 0.1 0.00045 20.6 0.1 1.5 1 1 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ORY58669.1 - 0.00029 21.0 0.3 0.00066 19.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 ORY58669.1 - 0.001 18.7 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 ORY58669.1 - 0.013 14.8 0.6 0.019 14.2 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 ORY58669.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ORY58669.1 - 0.016 15.1 0.1 0.025 14.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 ORY58669.1 - 0.024 13.3 0.2 0.024 13.3 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ORY58669.1 - 0.028 13.5 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY58669.1 - 0.029 13.6 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY58669.1 - 0.033 14.4 0.3 0.06 13.6 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_4 PF13439.6 ORY58669.1 - 0.038 14.0 0.0 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 F420_oxidored PF03807.17 ORY58669.1 - 0.083 13.5 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 ORY58669.1 - 0.088 11.8 0.6 0.12 11.4 0.1 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 ORY58669.1 - 0.12 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.15 ORY58669.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NPR3 PF03666.13 ORY58670.1 - 1.1e-96 324.5 0.0 1.3e-96 324.2 0.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 ORY58670.1 - 0.0008 18.3 0.0 0.27 9.9 0.0 3.2 4 0 0 4 4 4 2 Nitrogen permease regulator 2 Methyltransf_16 PF10294.9 ORY58671.1 - 4.7e-09 36.2 0.0 2.5e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY58671.1 - 4.5e-05 23.3 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY58671.1 - 6.4e-05 22.8 0.0 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY58671.1 - 0.018 15.8 0.0 1.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORY58671.1 - 0.042 14.6 0.0 6.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain RRM_1 PF00076.22 ORY58672.1 - 3.1e-16 59.0 0.0 4.4e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY58672.1 - 5.4e-08 32.5 0.0 5.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NmrA PF05368.13 ORY58673.1 - 2.3e-22 79.7 0.0 3.2e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY58673.1 - 1.6e-12 47.7 0.0 4.4e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORY58673.1 - 0.00016 22.0 0.2 0.00034 20.9 0.1 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 ORY58673.1 - 0.028 13.8 0.2 0.082 12.2 0.1 1.7 1 1 1 2 2 2 0 ThiF family Shikimate_DH PF01488.20 ORY58673.1 - 0.034 14.2 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ORY58673.1 - 0.082 12.6 0.5 0.61 9.7 0.2 2.1 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 ORY58673.1 - 0.18 11.3 0.0 12 5.2 0.0 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY58674.1 - 1.3e-20 73.9 0.0 1.8e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY58674.1 - 2.6e-12 47.0 0.0 1.2e-11 44.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 ORY58674.1 - 0.00049 20.2 0.0 0.00097 19.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY58674.1 - 0.00071 19.8 0.2 0.0018 18.5 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 ORY58674.1 - 0.0038 16.9 0.2 0.014 15.0 0.1 2.0 1 1 1 2 2 2 1 Ketopantoate reductase PanE/ApbA DUF4804 PF16062.5 ORY58674.1 - 0.041 12.7 0.0 0.089 11.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4804) NAD_binding_2 PF03446.15 ORY58674.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.21 ORY58674.1 - 0.073 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ThiF PF00899.21 ORY58674.1 - 0.12 11.8 0.3 0.4 10.0 0.4 1.8 1 1 1 2 2 2 0 ThiF family KR PF08659.10 ORY58674.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 KR domain DNA_pol_phi PF04931.13 ORY58675.1 - 9.1e-142 473.8 0.0 1.5e-141 473.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase phi Phage_fiber_2 PF03406.13 ORY58675.1 - 0.0096 15.5 0.0 0.032 13.8 0.0 1.9 1 0 0 1 1 1 1 Phage tail fibre repeat YtkA PF13115.6 ORY58675.1 - 1.2 9.8 7.5 6.3 7.5 7.9 2.1 2 0 0 2 2 2 0 YtkA-like MutS_V PF00488.21 ORY58677.1 - 1.6e-67 227.2 0.3 3.5e-67 226.1 0.3 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY58677.1 - 9.3e-36 123.8 0.0 5.8e-35 121.3 0.0 2.3 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.17 ORY58677.1 - 1.9e-12 47.6 0.1 4.1e-11 43.3 0.0 2.9 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 ORY58677.1 - 3.2e-11 43.5 0.0 6.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 ORY58677.1 - 2.9e-09 37.1 0.3 5.8e-09 36.2 0.3 1.5 1 0 0 1 1 1 1 MutS family domain IV UbiA PF01040.18 ORY58678.1 - 1.6e-53 181.6 16.3 2e-53 181.3 16.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.7 ORY58679.1 - 0.0004 20.2 0.0 0.00085 19.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like MIP PF00230.20 ORY58680.1 - 1.6e-49 168.6 7.6 2.4e-49 168.1 7.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein PelG PF16933.5 ORY58680.1 - 0.15 10.9 0.5 0.24 10.2 0.5 1.2 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) DUF3472 PF11958.8 ORY58680.1 - 0.16 12.4 0.2 0.3 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) HORMA PF02301.18 ORY58681.1 - 5.5e-61 205.8 0.0 1.1e-60 204.9 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 ORY58681.1 - 0.00043 20.1 15.8 0.00079 19.3 15.8 1.5 1 0 0 1 1 1 1 PHD-finger MarR_2 PF12802.7 ORY58681.1 - 0.0016 18.3 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 ORY58681.1 - 0.035 13.7 0.1 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.19 ORY58681.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain DEAD PF00270.29 ORY58683.1 - 1.4e-44 152.0 0.2 2.4e-44 151.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY58683.1 - 1.3e-32 112.4 0.0 8e-32 109.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY58683.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY58683.1 - 0.00015 22.2 0.1 0.0033 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY58683.1 - 0.00081 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 ORY58683.1 - 0.026 14.0 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 ORY58683.1 - 0.053 13.4 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 ORY58683.1 - 0.067 13.5 0.9 0.41 10.9 0.9 2.1 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 ORY58683.1 - 0.094 12.7 0.2 0.49 10.4 0.1 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain DUF5393 PF17371.2 ORY58683.1 - 0.1 10.7 0.1 0.14 10.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5393) DUF3449 PF11931.8 ORY58684.1 - 9.9e-71 237.3 0.1 3.8e-70 235.4 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 ORY58684.1 - 5.7e-23 81.2 0.1 1.9e-22 79.6 0.0 1.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 ORY58684.1 - 2.4e-09 36.9 0.5 6e-09 35.6 0.1 1.8 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 ORY58684.1 - 2.1e-07 31.1 5.3 2e-05 24.8 1.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY58684.1 - 6e-06 26.4 0.4 6e-06 26.4 0.4 2.5 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY58684.1 - 0.0042 17.4 0.8 0.07 13.5 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) POTRA PF07244.15 ORY58684.1 - 0.074 13.6 0.4 0.2 12.3 0.4 1.7 1 0 0 1 1 1 0 Surface antigen variable number repeat Laps PF10169.9 ORY58684.1 - 0.28 11.8 3.0 0.87 10.2 0.1 2.6 2 0 0 2 2 2 0 Learning-associated protein FRG1 PF06229.12 ORY58685.1 - 2.1e-19 70.0 5.3 9.4e-08 32.0 3.0 3.3 1 1 2 3 3 3 3 FRG1-like domain Fascin PF06268.13 ORY58685.1 - 4.8e-07 30.0 0.3 2e-06 28.0 0.0 2.1 3 0 0 3 3 3 1 Fascin domain DUF569 PF04601.13 ORY58685.1 - 0.00021 21.0 0.0 0.00074 19.2 0.0 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF569) Exo_endo_phos PF03372.23 ORY58686.1 - 3.7e-06 26.6 0.0 9.7e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 ORY58686.1 - 0.097 12.5 0.8 0.41 10.5 0.8 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF3295 PF11702.8 ORY58687.1 - 0.0029 17.0 0.6 0.0031 16.9 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) BURP PF03181.15 ORY58687.1 - 0.024 14.2 0.4 0.047 13.3 0.4 1.5 1 0 0 1 1 1 0 BURP domain DUF883 PF05957.13 ORY58687.1 - 0.05 14.2 5.0 2.6 8.7 0.4 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FAA_hydrolase_N PF09298.11 ORY58687.1 - 0.3 11.3 1.7 0.38 11.0 0.2 1.9 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal FKBP_N PF01346.18 ORY58687.1 - 6.3 7.8 8.6 3.2 8.8 1.1 2.5 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LUC7 PF03194.15 ORY58688.1 - 7.5e-66 222.3 3.8 7.5e-66 222.3 3.8 1.8 2 0 0 2 2 2 1 LUC7 N_terminus JmjC PF02373.22 ORY58689.1 - 7.4e-42 142.4 0.2 1.6e-41 141.3 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 ORY58689.1 - 3.4e-19 69.3 0.0 6.4e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 ORY58689.1 - 9.5e-15 54.3 2.6 9.5e-15 54.3 2.6 1.9 2 0 0 2 2 2 1 jmjN domain PHD PF00628.29 ORY58689.1 - 2.6e-12 46.4 9.2 7.7e-12 44.9 5.7 2.4 2 0 0 2 2 2 1 PHD-finger zf-C5HC2 PF02928.16 ORY58689.1 - 3.8e-09 36.8 0.5 1.1e-08 35.4 0.5 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 ORY58689.1 - 0.032 13.8 1.2 0.063 12.9 1.2 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 ORY58689.1 - 0.1 12.5 5.4 0.25 11.3 5.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 ORY58689.1 - 0.2 11.8 3.9 0.07 13.3 0.6 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_2 PF13639.6 ORY58689.1 - 0.85 10.0 8.5 2.2 8.7 8.5 1.8 1 0 0 1 1 1 0 Ring finger domain F-box PF00646.33 ORY58690.1 - 2.5e-06 27.2 0.5 1e-05 25.3 0.1 2.2 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY58690.1 - 0.0056 16.5 0.8 0.0056 16.5 0.8 2.9 4 0 0 4 4 4 1 F-box-like F-box-like_2 PF13013.6 ORY58690.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain tRNA_Me_trans PF03054.16 ORY58691.1 - 3.7e-103 345.0 0.0 4.2e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 ORY58691.1 - 0.0061 16.2 0.0 0.012 15.2 0.0 1.4 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.17 ORY58691.1 - 0.12 11.5 0.1 12 5.0 0.1 2.8 3 0 0 3 3 3 0 NAD synthase Mito_carr PF00153.27 ORY58692.1 - 9.4e-42 140.9 1.7 3.1e-14 52.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rrn6 PF10214.9 ORY58693.1 - 1.8e-16 59.9 23.8 4e-14 52.1 22.1 3.6 2 1 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor Zn_clus PF00172.18 ORY58693.1 - 0.067 13.3 3.0 0.14 12.3 3.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 ORY58694.1 - 7e-33 114.1 0.0 1e-32 113.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF863 PF05904.11 ORY58695.1 - 0.0095 14.4 2.1 0.013 14.0 2.1 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF863) Acyltransferase PF01553.21 ORY58696.1 - 2.2e-08 33.8 0.0 2.3e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Aa_trans PF01490.18 ORY59013.1 - 0.0047 15.7 0.6 8.2 5.0 0.0 3.1 3 0 0 3 3 3 3 Transmembrane amino acid transporter protein Mobilization_B PF17511.2 ORY59013.1 - 0.07 13.5 0.4 0.15 12.4 0.4 1.5 1 0 0 1 1 1 0 Mobilization protein B LtrA PF06772.11 ORY59014.1 - 3.6e-28 98.8 26.8 5.9e-28 98.1 26.8 1.3 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) RPN6_C_helix PF18503.1 ORY59014.1 - 0.054 13.2 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain Phostensin_N PF13916.6 ORY59015.1 - 0.0023 18.2 0.6 0.017 15.5 0.0 2.2 2 0 0 2 2 2 1 PP1-regulatory protein, Phostensin N-terminal Not1 PF04054.15 ORY59015.1 - 0.0098 14.8 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 Usp PF00582.26 ORY59016.1 - 1e-15 58.5 0.0 1.8e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family Ribosomal_60s PF00428.19 ORY59017.1 - 3.1 8.4 5.7 4.7 7.9 0.1 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein ABC_tran PF00005.27 ORY59019.1 - 1.4e-15 58.0 0.1 5.6e-15 56.1 0.0 2.0 2 1 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 ORY59019.1 - 8.1e-11 42.3 2.9 0.00014 21.8 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ORY59019.1 - 4.3e-05 23.2 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY59019.1 - 0.00045 20.2 0.6 0.0035 17.3 0.6 2.0 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 ORY59019.1 - 0.0023 17.6 0.1 0.0051 16.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY59019.1 - 0.0053 16.7 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY59019.1 - 0.011 15.9 0.1 0.02 14.9 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY59019.1 - 0.012 15.8 0.1 0.019 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 ORY59019.1 - 0.014 14.8 0.0 1.3 8.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY59019.1 - 0.018 14.8 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ORY59019.1 - 0.022 15.3 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY59019.1 - 0.032 14.5 0.1 0.08 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY59019.1 - 0.043 14.2 0.2 0.069 13.5 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 ORY59019.1 - 0.062 13.5 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY59019.1 - 0.067 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family PduV-EutP PF10662.9 ORY59019.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 ORY59019.1 - 0.16 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nop25 PF09805.9 ORY59020.1 - 9.7e-25 87.6 5.6 9.7e-25 87.6 5.6 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) zf-Tim10_DDP PF02953.15 ORY59025.1 - 1.1e-09 37.7 0.5 1.6e-09 37.2 0.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger eIF-6 PF01912.18 ORY59026.1 - 4.7e-80 267.6 0.1 6.1e-80 267.3 0.1 1.1 1 0 0 1 1 1 1 eIF-6 family eIF-6 PF01912.18 ORY59029.1 - 1.3e-07 31.2 0.0 2.3e-07 30.4 0.0 1.4 2 0 0 2 2 2 1 eIF-6 family Borrelia_P13 PF05628.12 ORY59029.1 - 0.12 12.3 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 Borrelia membrane protein P13 LtrA PF06772.11 ORY59032.1 - 1.5e-30 106.7 20.3 2.1e-30 106.1 20.3 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) MutS_V PF00488.21 ORY59033.1 - 5.5e-44 150.4 0.9 1.1e-43 149.5 0.9 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY59033.1 - 2.6e-23 83.3 0.3 6.1e-23 82.0 0.0 1.8 2 1 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 ORY59033.1 - 0.00048 20.4 0.0 0.00099 19.4 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV Pyr_redox_2 PF07992.14 ORY59035.1 - 1.2e-65 221.7 9.2 1.6e-65 221.3 9.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY59035.1 - 1.2e-37 128.5 0.1 4.1e-37 126.8 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY59035.1 - 4.5e-20 72.0 8.7 4.8e-17 62.3 2.6 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY59035.1 - 3.2e-11 43.0 6.7 2.9e-08 33.3 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY59035.1 - 6.7e-11 42.2 0.6 6.7e-11 42.2 0.6 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 ORY59035.1 - 1.8e-08 33.9 12.0 2.2e-08 33.6 4.3 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY59035.1 - 1.7e-07 30.7 2.2 1.7e-07 30.7 2.2 3.5 2 1 2 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 ORY59035.1 - 2.8e-07 30.7 5.8 2.4e-05 24.5 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY59035.1 - 1.1e-06 27.6 12.4 8.9e-05 21.4 1.1 4.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.17 ORY59035.1 - 2.4e-06 27.0 6.3 0.00018 20.9 0.1 2.6 2 0 0 2 2 2 2 Thi4 family AlaDh_PNT_C PF01262.21 ORY59035.1 - 1.5e-05 24.4 4.9 0.057 12.7 0.2 3.0 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 ORY59035.1 - 2.2e-05 23.8 0.7 0.11 11.6 0.1 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ORY59035.1 - 0.0012 18.2 9.7 0.012 14.9 0.8 3.2 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.24 ORY59035.1 - 0.0031 17.2 11.6 0.16 11.5 0.5 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase THF_DHG_CYH_C PF02882.19 ORY59035.1 - 0.0053 16.1 1.6 0.042 13.2 0.6 2.8 2 1 1 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 ORY59035.1 - 0.39 9.7 6.7 0.23 10.4 0.6 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein Zn_clus PF00172.18 ORY59037.1 - 1.4e-07 31.5 7.6 2e-07 31.0 7.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.26 ORY59038.1 - 2.8e-26 92.2 0.0 5.5e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY59038.1 - 8.4e-25 87.1 0.3 2.2e-24 85.8 0.3 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 ORY59038.1 - 3e-16 59.5 0.0 6.4e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ORY59038.1 - 4.4e-16 59.1 0.0 5.6e-09 36.2 0.0 4.1 3 0 0 3 3 3 3 PAS fold HisKA PF00512.25 ORY59038.1 - 4.9e-13 48.9 0.0 1.4e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ORY59038.1 - 3.5e-08 33.6 0.0 2.3e-06 27.8 0.0 2.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY59038.1 - 2.1e-05 24.5 0.0 0.0022 18.0 0.0 2.9 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 ORY59038.1 - 0.0015 18.3 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 ORY59038.1 - 0.0019 18.2 0.0 0.028 14.5 0.0 2.9 2 0 0 2 2 2 1 PAS domain PQ-loop PF04193.14 ORY59039.1 - 1.4e-31 108.0 9.2 1.1e-15 57.1 3.4 2.5 2 0 0 2 2 2 2 PQ loop repeat YrhC PF14143.6 ORY59039.1 - 0.038 14.1 0.1 0.12 12.5 0.1 1.8 1 0 0 1 1 1 0 YrhC-like protein Pkinase PF00069.25 ORY59040.1 - 5.5e-60 203.0 0.0 6.5e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY59040.1 - 7.6e-31 107.3 0.0 9.3e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY59040.1 - 1.7e-05 24.3 0.1 3.6e-05 23.2 0.0 1.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORY59040.1 - 0.00055 19.9 0.0 0.37 10.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY59040.1 - 0.0042 16.5 0.0 0.0096 15.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY59040.1 - 0.015 14.9 0.2 0.74 9.4 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AA_permease PF00324.21 ORY59041.1 - 1.2e-129 433.0 36.8 1.5e-129 432.7 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY59041.1 - 1.4e-38 132.9 39.6 1.7e-38 132.6 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease zf-ANAPC11 PF12861.7 ORY59042.1 - 3.2e-41 139.3 5.8 4.1e-41 139.0 5.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY59042.1 - 4.8e-22 78.0 12.3 8e-22 77.3 12.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY59042.1 - 0.00067 19.9 17.3 0.0062 16.8 17.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-Nse PF11789.8 ORY59042.1 - 0.051 13.4 3.2 0.08 12.8 3.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 ORY59042.1 - 0.069 13.0 14.7 0.31 11.0 14.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY59042.1 - 0.1 12.2 14.7 0.54 9.9 14.7 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ribosomal_60s PF00428.19 ORY59042.1 - 0.26 11.9 10.3 0.19 12.3 4.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-RING_5 PF14634.6 ORY59042.1 - 0.37 10.8 13.9 7.5 6.6 14.6 2.5 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY59042.1 - 0.82 9.8 12.9 1.6 8.8 12.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY59042.1 - 0.84 9.5 18.4 0.58 10.0 14.5 2.5 1 1 1 2 2 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 ORY59042.1 - 1 9.5 10.7 5 7.3 10.8 2.2 1 1 0 1 1 1 0 RING-variant domain zf-RING_11 PF17123.5 ORY59042.1 - 4.9 7.0 13.6 0.46 10.3 8.2 2.0 2 0 0 2 2 2 0 RING-like zinc finger Sugar_tr PF00083.24 ORY59043.1 - 5.7e-87 292.5 34.0 7.2e-87 292.1 34.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY59043.1 - 1.4e-14 53.8 55.1 4.9e-13 48.7 22.8 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily RGS12_usC PF16612.5 ORY59043.1 - 0.56 10.6 6.3 0.97 9.9 6.3 1.3 1 0 0 1 1 1 0 C-terminal unstructured region of RGS12 CLTH PF10607.9 ORY59406.1 - 6.2e-12 45.6 0.0 1.4e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain FAM199X PF15814.5 ORY59406.1 - 2.2 7.2 6.1 4.2 6.3 6.1 1.4 1 0 0 1 1 1 0 Protein family FAM199X UCR_UQCRX_QCR9 PF05365.12 ORY59407.1 - 2.1e-23 82.0 4.0 2.5e-23 81.8 4.0 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF3464 PF11947.8 ORY59407.1 - 0.012 15.3 0.1 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 GLTP PF08718.11 ORY59408.1 - 1.9e-48 164.5 0.3 2.4e-48 164.2 0.3 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Ctr PF04145.15 ORY59409.1 - 1.7e-17 64.4 0.3 2.5e-17 63.9 0.3 1.2 1 0 0 1 1 1 1 Ctr copper transporter family GATA PF00320.27 ORY59410.1 - 4.1e-15 55.1 2.1 7e-15 54.3 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORY59410.1 - 2.7e-14 53.2 0.0 6.7e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 ORY59410.1 - 1.4e-11 44.4 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ORY59410.1 - 2e-07 31.2 0.0 4.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 ORY59410.1 - 4.6e-06 26.7 0.0 4.6e-06 26.7 0.0 1.9 3 0 0 3 3 3 1 PAS domain PAS_9 PF13426.7 ORY59410.1 - 2.7e-05 24.4 0.0 0.00011 22.4 0.0 1.9 1 1 1 2 2 2 1 PAS domain Zn-ribbon_8 PF09723.10 ORY59410.1 - 0.011 15.8 0.4 0.021 14.9 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 ORY59410.1 - 0.04 13.4 0.1 0.04 13.4 0.1 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding RPA_C PF08784.11 ORY59412.1 - 3.6e-10 40.4 0.1 7.8e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 ORY59412.1 - 2.7e-06 27.3 0.4 4.2e-06 26.6 0.4 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Methyltransf_11 PF08241.12 ORY59413.1 - 5.2e-20 71.9 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY59413.1 - 1.1e-18 67.7 0.0 4.4e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY59413.1 - 6.3e-13 49.3 0.0 1.2e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY59413.1 - 1.8e-12 47.3 0.0 2.6e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY59413.1 - 7.4e-10 38.9 0.0 1.1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY59413.1 - 2.2e-07 30.5 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DREV PF05219.12 ORY59413.1 - 6.5e-05 22.1 0.0 9.9e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 ORY59413.1 - 0.0019 17.5 0.0 0.0027 17.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 ORY59413.1 - 0.048 13.1 0.0 6.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase NodS PF05401.11 ORY59413.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 ORY59413.1 - 0.22 11.4 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase PhoLip_ATPase_C PF16212.5 ORY59414.1 - 8.6e-78 261.5 26.5 8.6e-78 261.5 26.5 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY59414.1 - 2.7e-22 78.2 1.1 6.6e-22 77.0 1.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORY59414.1 - 5.1e-13 49.8 0.4 6.4e-06 26.6 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY59414.1 - 1.7e-09 37.6 0.0 5.7e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY59414.1 - 4e-05 23.5 1.1 0.0015 18.3 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY59414.1 - 6.9e-05 22.4 0.7 0.00052 19.6 0.0 2.9 3 1 0 3 3 3 1 E1-E2 ATPase GST_C_3 PF14497.6 ORY59415.1 - 1.7e-23 82.7 0.2 3.1e-23 81.8 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY59415.1 - 0.015 15.6 0.0 0.037 14.4 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY59415.1 - 0.019 14.9 0.2 0.051 13.6 0.2 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY59415.1 - 0.046 13.9 0.1 0.077 13.2 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SnoaL_2 PF12680.7 ORY59416.1 - 0.00088 19.9 0.0 0.0012 19.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain WI12 PF07107.11 ORY59416.1 - 0.006 16.7 0.2 0.013 15.6 0.2 1.5 1 1 0 1 1 1 1 Wound-induced protein WI12 QRPTase_C PF01729.19 ORY59416.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain RNase_H PF00075.24 ORY59417.1 - 2e-17 63.7 0.0 6.3e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 RNase H Acetyltransf_2 PF00797.17 ORY59418.1 - 7.4e-21 75.0 0.0 2.4e-17 63.5 0.0 3.1 2 1 0 2 2 2 2 N-acetyltransferase Alk_phosphatase PF00245.20 ORY59419.1 - 2.6e-64 217.7 0.0 3.3e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 ORY59419.1 - 1.1e-06 28.5 0.4 1.5e-06 28.0 0.4 1.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY59419.1 - 7e-06 25.6 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 ORY59419.1 - 0.08 11.5 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 ORY59419.1 - 0.12 11.7 0.4 0.3 10.4 0.2 1.7 2 0 0 2 2 2 0 Metalloenzyme superfamily Pmp3 PF01679.17 ORY59420.1 - 4.9e-12 45.8 5.2 7.3e-12 45.3 5.2 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF5373 PF17343.2 ORY59421.1 - 0.032 14.1 14.0 1.2 9.0 8.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5373) Methyltransf_PK PF05891.12 ORY59422.1 - 1.8e-55 187.8 0.0 2.8e-32 112.0 0.0 2.2 2 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORY59422.1 - 0.00013 22.6 0.0 1.1 10.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORY59422.1 - 0.025 15.3 0.0 0.47 11.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY59422.1 - 0.14 12.8 0.0 17 6.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain VCBS PF13517.6 ORY59424.1 - 2.3e-27 95.4 7.5 9.4e-09 35.7 0.2 6.1 5 2 1 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ORY59424.1 - 7.1e-06 26.0 13.5 0.27 11.4 0.0 6.3 6 0 0 6 6 6 2 FG-GAP repeat TcdB_toxin_midN PF12256.8 ORY59424.1 - 0.025 13.9 3.2 19 4.6 0.1 4.5 4 1 1 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region SfLAP PF11139.8 ORY59424.1 - 0.058 12.8 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF166 PF02593.14 ORY59424.1 - 0.22 11.0 0.0 0.49 9.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function zf-Mss51 PF13824.6 ORY59425.1 - 2.2e-21 75.7 2.5 3.9e-21 74.9 2.5 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF2407_C PF13373.6 ORY59426.1 - 6.4e-22 78.2 0.4 1.6e-21 76.9 0.4 1.7 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 ORY59426.1 - 2.6e-08 34.4 0.0 7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain VIT1 PF01988.19 ORY59426.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 VIT family Gluconate_2-dh3 PF13618.6 ORY59426.1 - 0.15 12.3 0.4 1.3 9.3 0.4 2.1 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 GPI-anchored PF10342.9 ORY59427.1 - 0.00031 21.4 1.5 0.00038 21.2 1.5 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2909 PF11137.8 ORY59427.1 - 0.17 11.8 0.3 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) SET PF00856.28 ORY59428.1 - 1.5e-06 28.7 0.0 4.4e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 SET domain Smg4_UPF3 PF03467.15 ORY59429.1 - 1.7e-45 155.1 0.2 5.8e-45 153.4 0.0 2.0 2 0 0 2 2 2 1 Smg-4/UPF3 family PAT1 PF09770.9 ORY59429.1 - 1.1 7.5 15.9 1.7 6.8 15.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ORC3_N PF07034.11 ORY59430.1 - 5.5e-54 183.5 0.0 1.7e-53 181.9 0.0 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 ORY59430.1 - 9.4e-24 84.1 0.7 1.5e-23 83.4 0.0 1.7 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal CoA_transf_3 PF02515.17 ORY59431.1 - 0.016 14.3 0.1 0.02 14.0 0.1 1.1 1 0 0 1 1 1 0 CoA-transferase family III Histone_HNS PF00816.21 ORY59431.1 - 0.023 15.5 0.1 0.046 14.5 0.1 1.6 1 1 0 1 1 1 0 H-NS histone family Lipase_GDSL_lke PF16255.5 ORY59431.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Vps23_core PF09454.10 ORY59432.1 - 1.1e-26 92.6 0.1 1.7e-26 91.9 0.1 1.4 1 0 0 1 1 1 1 Vps23 core domain UEV PF05743.13 ORY59432.1 - 2e-25 89.0 0.0 3.1e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 UEV domain BTB PF00651.31 ORY59432.1 - 8.9e-05 22.7 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain UQ_con PF00179.26 ORY59432.1 - 0.034 13.8 0.1 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Kinesin PF00225.23 ORY59433.1 - 8.8e-97 324.0 3.8 7e-53 179.7 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 ORY59433.1 - 1.4e-23 83.5 0.0 5.9e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding DUF1664 PF07889.12 ORY59433.1 - 0.018 15.1 0.3 0.018 15.1 0.3 9.5 7 4 2 9 9 9 0 Protein of unknown function (DUF1664) Dynamin_M PF01031.20 ORY59435.1 - 3.6e-104 348.0 0.0 6.3e-104 347.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 ORY59435.1 - 1.8e-54 184.3 0.0 3.3e-54 183.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY59435.1 - 3.4e-26 91.2 1.1 7.6e-26 90.1 1.1 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY59435.1 - 0.00016 21.7 0.0 0.0004 20.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY59435.1 - 0.15 12.5 0.0 0.84 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_15 PF13175.6 ORY59435.1 - 0.16 11.6 1.0 4 7.1 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain GLTP PF08718.11 ORY59437.1 - 3.1e-30 105.4 0.0 4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) HTH_15 PF12324.8 ORY59437.1 - 0.06 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase ECH_2 PF16113.5 ORY59438.1 - 3.1e-107 358.9 0.0 4.4e-107 358.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY59438.1 - 2.7e-27 95.7 0.1 4.9e-27 94.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF4895 PF16236.5 ORY59438.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4895) NUDIX PF00293.28 ORY59439.1 - 7.8e-19 68.0 0.2 9.3e-19 67.8 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain Exo_endo_phos PF03372.23 ORY59440.1 - 9.9e-15 54.7 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family tRNA_anti-codon PF01336.25 ORY59440.1 - 9.5e-07 28.7 0.0 3e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain REPA_OB_2 PF16900.5 ORY59440.1 - 3.6e-05 23.6 0.0 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 Replication protein A OB domain PQ-loop PF04193.14 ORY59441.1 - 3.6e-24 84.3 3.2 9.6e-19 66.9 0.5 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 ORY59441.1 - 0.0054 16.7 0.2 0.0054 16.7 0.2 2.0 2 1 1 3 3 3 1 Sugar efflux transporter for intercellular exchange Rod_cone_degen PF15201.6 ORY59441.1 - 0.068 13.3 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 Progressive rod-cone degeneration CAF1A PF12253.8 ORY59442.1 - 9.3e-23 80.2 2.7 9.3e-23 80.2 2.7 3.5 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A Cyclin PF08613.11 ORY59442.1 - 0.53 10.6 2.9 0.58 10.5 0.1 2.3 2 0 0 2 2 2 0 Cyclin LMBR1 PF04791.16 ORY59442.1 - 0.81 8.5 5.6 1.1 8.1 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein SOBP PF15279.6 ORY59442.1 - 2.6 8.6 30.1 0.87 10.1 15.4 2.6 2 0 0 2 2 2 0 Sine oculis-binding protein AAA PF00004.29 ORY59443.1 - 1.3e-16 61.2 0.0 2.5e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 ORY59443.1 - 1.9e-15 57.1 0.1 4.8e-15 55.7 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORY59443.1 - 8.7e-14 51.6 0.0 1.9e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ORY59443.1 - 1.2e-07 31.8 0.1 2.5e-07 30.8 0.0 1.5 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 ORY59443.1 - 2.8e-05 24.4 0.0 7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 ORY59443.1 - 3.6e-05 23.7 0.1 0.0001 22.2 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY59443.1 - 3.9e-05 24.0 0.2 0.0066 16.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY59443.1 - 4e-05 24.1 0.0 0.0061 16.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY59443.1 - 0.00081 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ORY59443.1 - 0.0014 18.0 0.0 0.041 13.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY59443.1 - 0.0016 18.5 0.0 0.0055 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 ORY59443.1 - 0.0016 18.2 0.0 0.0082 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY59443.1 - 0.0017 18.1 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY59443.1 - 0.0024 18.2 0.0 0.015 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY59443.1 - 0.0036 17.3 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY59443.1 - 0.0041 17.1 0.0 0.075 13.0 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 ORY59443.1 - 0.0091 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY59443.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 ORY59443.1 - 0.033 13.3 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 ORY59443.1 - 0.061 13.8 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY59443.1 - 0.087 13.4 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 ORY59443.1 - 0.094 12.5 0.3 0.95 9.2 0.1 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_3 PF07726.11 ORY59443.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY59443.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 ORY59443.1 - 0.17 11.1 0.0 0.57 9.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-C2H2 PF00096.26 ORY59444.1 - 5.4e-18 64.4 16.1 9.7e-06 25.8 1.0 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY59444.1 - 7.5e-18 64.1 14.3 3.5e-06 27.2 1.0 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY59444.1 - 3e-09 36.9 14.5 0.0048 17.6 1.0 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY59444.1 - 1.2e-06 28.7 2.8 0.05 13.9 0.1 3.5 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY59444.1 - 1.3e-05 25.4 4.4 0.11 12.9 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY59444.1 - 2.1e-05 24.7 3.0 3.6e-05 24.0 3.0 1.3 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORY59444.1 - 0.0018 18.9 0.8 0.0018 18.9 0.8 1.9 1 1 1 2 2 2 2 TRAF-type zinc finger zf-C2H2_11 PF16622.5 ORY59444.1 - 0.0052 16.5 0.9 0.0052 16.5 0.9 2.5 3 0 0 3 3 3 1 zinc-finger C2H2-type CHORD PF04968.12 ORY59444.1 - 0.025 15.3 6.8 0.58 10.9 2.2 3.0 1 1 1 2 2 2 0 CHORD BolA PF01722.18 ORY59444.1 - 0.068 13.5 1.4 0.12 12.6 0.2 1.9 2 1 0 2 2 2 0 BolA-like protein zf-HYPF PF07503.12 ORY59444.1 - 0.11 12.3 2.5 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 HypF finger zf-LYAR PF08790.11 ORY59444.1 - 0.14 12.1 5.3 0.98 9.4 0.3 3.3 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-CGNR PF11706.8 ORY59444.1 - 0.22 11.4 7.0 4.8 7.1 0.0 3.1 3 0 0 3 3 3 0 CGNR zinc finger XPA_N PF01286.18 ORY59444.1 - 0.86 9.7 5.5 0.75 9.9 0.4 2.9 3 0 0 3 3 3 0 XPA protein N-terminal MTHFR PF02219.17 ORY59446.1 - 1.8e-69 234.3 0.1 4.8e-69 232.8 0.0 1.6 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Alk_phosphatase PF00245.20 ORY59447.1 - 1.3e-15 57.3 0.2 1.6e-12 47.1 0.2 2.1 2 0 0 2 2 2 2 Alkaline phosphatase Mito_carr PF00153.27 ORY59875.1 - 5.4e-54 180.1 3.7 1.1e-24 86.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 ORY59875.1 - 0.057 13.2 0.8 0.15 11.8 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) PINIT PF14324.6 ORY59876.1 - 2e-33 115.8 0.3 3.3e-33 115.1 0.3 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 ORY59876.1 - 2.7e-18 65.4 1.4 5.2e-18 64.5 1.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY59876.1 - 3.5e-07 29.9 0.9 1.2e-06 28.2 0.4 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit AAA_12 PF13087.6 ORY59878.1 - 3.3e-61 206.4 0.0 5.1e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY59878.1 - 3.9e-46 158.0 0.0 7.8e-46 157.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY59878.1 - 1.4e-11 44.9 0.1 1.8e-10 41.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY59878.1 - 2e-11 44.0 0.0 6e-10 39.2 0.0 2.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY59878.1 - 3.8e-06 26.8 0.0 0.38 10.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 ORY59878.1 - 0.0081 16.0 0.1 0.084 12.7 0.0 2.5 3 0 0 3 3 3 1 Helicase WD40 PF00400.32 ORY59879.1 - 9.2e-19 67.5 9.7 7.4e-06 26.6 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.12 ORY59879.1 - 1.1e-18 67.5 0.4 2.4e-18 66.4 0.0 1.8 2 0 0 2 2 2 1 NLE (NUC135) domain GTP_EFTU PF00009.27 ORY59880.1 - 1.1e-53 181.7 0.1 1.7e-53 181.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY59880.1 - 3e-42 143.5 0.0 6.8e-42 142.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY59880.1 - 6.8e-14 52.0 1.1 6.8e-14 52.0 1.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY59880.1 - 0.00056 20.0 0.4 0.015 15.4 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase L-fibroin PF05849.11 ORY59880.1 - 0.093 12.0 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Fibroin light chain (L-fibroin) NIF3 PF01784.18 ORY59880.1 - 0.096 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) GTP_EFTU_D4 PF14578.6 ORY59880.1 - 0.12 12.3 2.0 0.14 12.0 0.5 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Ribosomal_L32e PF01655.18 ORY59881.1 - 1.1e-06 29.0 0.4 1.8e-06 28.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 GTP_EFTU_D3 PF03143.17 ORY59883.1 - 6.6e-09 36.1 0.0 9.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Ribosomal_L32e PF01655.18 ORY59884.1 - 4.9e-46 155.6 0.5 5.9e-46 155.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 CSD PF00313.22 ORY59885.1 - 1.6e-13 50.3 0.1 2.6e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain F-box-like PF12937.7 ORY59886.1 - 5.2e-06 26.3 0.3 1.2e-05 25.1 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY59886.1 - 0.12 12.8 6.1 51 4.5 0.5 5.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.13 ORY59886.1 - 0.7 10.7 2.4 1.1e+02 3.7 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat AhpC-TSA PF00578.21 ORY59887.1 - 1.6e-39 134.6 0.0 2.5e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY59887.1 - 7.4e-16 58.2 0.0 1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY59887.1 - 7.9e-10 38.4 0.1 1.7e-09 37.3 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 ORY59887.1 - 0.027 14.4 0.2 0.082 12.8 0.1 1.8 2 0 0 2 2 2 0 SCO1/SenC GATase PF00117.28 ORY59888.1 - 1.1e-10 41.6 0.0 4.9e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ORY59888.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_2 PF00310.21 ORY59889.1 - 4.3e-177 589.0 0.0 5.6e-177 588.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ORY59889.1 - 7e-157 522.3 0.5 6.5e-156 519.1 0.0 2.4 3 0 0 3 3 3 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ORY59889.1 - 1.1e-113 379.4 0.0 5.9e-112 373.7 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 ORY59889.1 - 1.8e-86 288.6 2.9 2.9e-86 287.9 2.9 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 ORY59889.1 - 7.2e-24 84.5 0.0 1.8e-23 83.2 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 ORY59889.1 - 6.1e-22 77.5 0.3 1.3e-21 76.5 0.3 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 ORY59889.1 - 6.2e-09 36.0 0.0 2e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY59889.1 - 1.7e-08 34.1 0.0 1.3e-05 24.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY59889.1 - 9.3e-08 32.5 0.1 5.9e-05 23.6 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY59889.1 - 1.5e-06 28.1 0.1 0.002 17.8 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY59889.1 - 4.1e-05 22.5 0.1 4.1e-05 22.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 ORY59889.1 - 6e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORY59889.1 - 7.1e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 ORY59889.1 - 0.00029 20.2 0.0 0.00058 19.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 ORY59889.1 - 0.0003 20.0 2.0 0.00097 18.3 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY59889.1 - 0.00082 18.7 0.1 0.049 12.9 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORY59889.1 - 0.002 18.5 0.8 0.44 11.0 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding IlvN PF07991.12 ORY59889.1 - 0.0079 15.8 0.2 0.29 10.7 0.1 2.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 ORY59889.1 - 0.013 14.6 2.7 0.095 11.8 0.2 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A FMN_dh PF01070.18 ORY59889.1 - 0.014 14.4 0.9 0.034 13.2 0.9 1.6 1 0 0 1 1 1 0 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.19 ORY59889.1 - 0.021 14.2 0.2 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 ORY59889.1 - 0.024 13.9 0.1 0.054 12.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.23 ORY59889.1 - 0.1 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 ORY59889.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORY59889.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_9 PF13454.6 ORY59889.1 - 0.14 12.2 0.0 0.57 10.2 0.0 2.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding GATase_6 PF13522.6 ORY59889.1 - 0.15 12.3 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Lycopene_cycl PF05834.12 ORY59889.1 - 0.17 10.9 0.0 0.45 9.5 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein zf-MYND PF01753.18 ORY59890.1 - 1.1e-09 38.1 15.8 2e-09 37.4 15.8 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY59890.1 - 0.14 12.5 8.1 0.28 11.5 8.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CSD PF00313.22 ORY59892.1 - 3e-16 59.0 0.1 3e-16 59.0 0.1 1.7 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain DUF1556 PF07590.11 ORY59892.1 - 0.45 10.8 2.7 0.43 10.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) MFS_1 PF07690.16 ORY59893.1 - 4e-08 32.6 29.1 9e-08 31.4 29.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.7 ORY59894.1 - 3.2e-07 30.1 0.1 1.1e-06 28.4 0.1 2.1 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY59894.1 - 0.041 14.0 0.1 44 4.5 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat PfkB PF00294.24 ORY59895.1 - 2.6e-37 128.7 0.0 3e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MoaE PF02391.17 ORY59899.1 - 3.4e-39 133.6 0.0 4.5e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 MoaE protein DUF1490 PF07371.12 ORY59899.1 - 0.099 12.7 0.4 0.39 10.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) Ribosomal_L13e PF01294.18 ORY59900.1 - 2.4e-73 245.8 3.9 3.6e-73 245.2 3.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e WD40 PF00400.32 ORY59903.1 - 4.3e-44 147.6 15.4 4.3e-12 46.3 0.5 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY59903.1 - 7.1e-17 61.5 2.0 2.6e-05 24.4 0.1 5.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 ORY59903.1 - 5.6e-06 25.0 0.0 1.9e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 ORY59903.1 - 3.7e-05 22.6 0.7 0.018 13.8 0.0 3.2 1 1 3 4 4 4 2 Nup133 N terminal like PALB2_WD40 PF16756.5 ORY59903.1 - 7e-05 21.9 0.1 7e-05 21.9 0.1 2.8 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 ORY59903.1 - 8.5e-05 21.7 1.4 4.2 6.2 0.0 4.8 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 ORY59903.1 - 9e-05 22.5 0.0 0.016 15.2 0.0 3.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 ORY59903.1 - 0.0011 17.7 6.9 0.19 10.4 0.1 4.0 3 1 0 4 4 4 1 Nucleoporin Nup120/160 Hira PF07569.11 ORY59903.1 - 0.002 17.9 0.2 3.2 7.4 0.0 3.3 1 1 2 3 3 3 2 TUP1-like enhancer of split eIF2A PF08662.11 ORY59903.1 - 0.0065 16.4 1.2 0.86 9.5 0.0 3.1 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 ORY59903.1 - 0.043 12.9 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Med3 PF11593.8 ORY59903.1 - 4.8 6.3 11.2 0.14 11.3 4.6 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SLATT_1 PF18181.1 ORY59904.1 - 0.74 9.8 2.8 1.7 8.6 0.0 2.6 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 RNA_pol_Rbc25 PF08292.12 ORY59905.1 - 9.7e-30 103.5 0.0 1.4e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 ORY59905.1 - 8.1e-18 64.6 0.1 2.2e-17 63.2 0.0 1.8 3 0 0 3 3 3 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORY59905.1 - 0.07 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain DEC-1_N PF04625.13 ORY59905.1 - 5.8 5.8 8.8 9.3 5.1 8.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Kinesin PF00225.23 ORY59906.1 - 6.9e-95 317.8 0.0 1.6e-94 316.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY59906.1 - 9.8e-21 74.2 0.0 2.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Spc7 PF08317.11 ORY59906.1 - 2.7e-05 23.2 29.6 2.7e-05 23.2 29.6 5.7 3 1 4 7 7 7 1 Spc7 kinetochore protein CCDC92 PF14916.6 ORY59906.1 - 2.2 8.1 12.0 0.93 9.3 0.3 3.8 4 0 0 4 4 4 0 Coiled-coil domain of unknown function CPSase_L_D2 PF02786.17 ORY59908.1 - 2.6e-67 226.4 0.0 4.4e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY59908.1 - 1.9e-44 150.7 0.0 4.8e-44 149.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY59908.1 - 3.4e-37 126.9 0.0 6.4e-37 126.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY59908.1 - 5.7e-15 54.9 0.3 1.7e-14 53.4 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY59908.1 - 2e-10 40.6 0.0 4.4e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY59908.1 - 5.4e-08 32.6 0.0 2e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain HlyD_3 PF13437.6 ORY59908.1 - 3.7e-05 24.4 1.3 0.036 14.8 0.2 2.8 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.14 ORY59908.1 - 0.0001 22.4 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 ORY59908.1 - 0.0037 17.1 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.6 ORY59908.1 - 0.0037 17.1 0.1 0.017 14.9 0.0 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 ORY59908.1 - 0.099 11.8 0.1 9.8 5.3 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ABC2_membrane PF01061.24 ORY59909.1 - 4.5e-77 258.2 55.9 9.4e-39 133.0 30.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORY59909.1 - 4.4e-34 117.9 0.0 3.9e-16 59.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY59909.1 - 9.1e-22 76.8 1.0 7.5e-21 73.8 0.0 2.9 3 0 0 3 3 3 1 CDR ABC transporter ABC_trans_N PF14510.6 ORY59909.1 - 2e-15 57.2 0.1 5.3e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 ORY59909.1 - 1.2e-06 27.9 21.0 1.2e-06 27.9 21.0 2.5 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.6 ORY59909.1 - 2.7e-06 27.6 0.6 0.0059 16.8 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_21 PF13304.6 ORY59909.1 - 6.2e-05 22.9 0.1 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY59909.1 - 0.00019 21.4 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORY59909.1 - 0.001 18.7 1.6 0.019 14.7 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY59909.1 - 0.0019 17.8 0.9 0.066 12.8 0.3 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY59909.1 - 0.0024 18.3 2.4 0.11 12.9 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY59909.1 - 0.0027 18.2 0.1 0.063 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ORY59909.1 - 0.0029 17.1 0.0 0.58 9.6 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY59909.1 - 0.043 14.1 1.1 2 8.7 0.3 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ORY59909.1 - 0.088 13.2 0.6 9.7 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY59909.1 - 0.14 12.6 1.4 0.38 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORY59909.1 - 0.33 10.9 3.1 7.9 6.4 0.3 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 ORY59909.1 - 1.1 8.9 5.1 1.3 8.6 1.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORY59909.1 - 1.3 8.7 3.5 6.1 6.5 0.5 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY59909.1 - 4.5 7.5 5.6 0.76 10.0 0.1 2.5 3 0 0 3 3 2 0 AAA domain Palm_thioest PF02089.15 ORY59910.1 - 2.4e-71 240.4 0.0 3e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase ResIII PF04851.15 ORY59911.1 - 9.6e-21 74.5 0.0 7.6e-20 71.6 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY59911.1 - 7.9e-15 55.2 0.0 7.9e-14 51.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY59911.1 - 8.4e-12 45.2 0.0 5.1e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY59911.1 - 5.7e-05 22.9 0.0 9.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 ORY59911.1 - 0.00026 21.3 0.0 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain SNF2_N PF00176.23 ORY59911.1 - 0.00027 19.8 0.0 0.00047 19.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.9 ORY59911.1 - 0.00092 18.5 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 ORY59911.1 - 0.041 13.7 12.0 0.11 12.3 0.0 3.6 3 1 1 4 4 4 0 AAA domain PapC_C PF13953.6 ORY59911.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 PapC C-terminal domain DUF3500 PF12006.8 ORY59911.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) AAA_16 PF13191.6 ORY59911.1 - 0.086 13.2 0.1 0.086 13.2 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 ORY59911.1 - 0.095 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.6 ORY59911.1 - 0.1 12.8 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain Yos1 PF08571.10 ORY59912.1 - 4.2e-27 94.2 0.1 1.9e-26 92.1 0.1 1.8 1 1 0 1 1 1 1 Yos1-like zf-RING_4 PF14570.6 ORY60367.1 - 2.5e-21 75.2 13.3 4.1e-21 74.5 13.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY60367.1 - 9.7e-07 28.6 7.5 1.6e-06 27.9 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 ORY60367.1 - 0.00052 20.0 0.5 0.00084 19.3 0.5 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 ORY60367.1 - 0.0026 18.1 11.1 0.0045 17.3 11.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 ORY60367.1 - 0.0047 17.0 3.3 0.0096 16.0 3.3 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4 PF00097.25 ORY60367.1 - 0.026 14.4 12.0 0.046 13.6 12.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY60367.1 - 0.032 14.1 9.0 0.77 9.7 9.6 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY60367.1 - 1 9.4 10.0 2.4 8.2 10.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY60367.1 - 1.9 8.4 11.0 3.6 7.5 11.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Plasmodium_Vir PF05795.11 ORY60367.1 - 3.5 7.0 6.4 8 5.8 6.4 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein F-box-like PF12937.7 ORY60368.1 - 0.0019 18.0 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY60368.1 - 0.0049 16.7 0.3 0.0085 16.0 0.0 1.6 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY60368.1 - 0.03 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 F-box Glucosamine_iso PF01182.20 ORY60369.1 - 5.7e-63 212.8 0.0 6.7e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Peptidase_M13_N PF05649.13 ORY60370.1 - 8.2e-100 335.1 0.0 1.2e-99 334.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY60370.1 - 5.6e-62 209.0 0.1 8.5e-62 208.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 F-box-like PF12937.7 ORY60371.1 - 9.3e-06 25.4 0.1 1.9e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY60371.1 - 0.0019 18.0 0.0 0.0065 16.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 ORY60371.1 - 0.005 16.4 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 F-box MFS_1 PF07690.16 ORY60373.1 - 4.8e-19 68.5 46.8 1.7e-14 53.5 36.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY60373.1 - 1.4e-16 60.4 18.1 5.5e-14 51.9 6.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.32 ORY60374.1 - 9.3e-40 133.9 31.4 4.9e-07 30.3 0.2 9.4 9 1 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.7 ORY60374.1 - 1.7e-12 47.1 0.0 5.5e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY60374.1 - 1.9e-08 34.0 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 ORY60374.1 - 4.1e-08 32.3 16.4 0.024 13.3 0.2 5.7 2 2 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY60374.1 - 4.7e-05 23.6 0.8 4.9 7.5 0.0 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY60374.1 - 0.00023 20.1 0.4 0.94 8.1 0.0 3.1 3 0 0 3 3 3 2 Nup133 N terminal like F-box_4 PF15966.5 ORY60374.1 - 0.006 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box Bim_N PF06773.11 ORY60374.1 - 0.021 14.5 0.2 0.12 12.1 0.2 2.3 1 0 0 1 1 1 0 Bim protein N-terminus Ge1_WD40 PF16529.5 ORY60374.1 - 0.14 11.1 1.2 13 4.6 0.0 3.2 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HEAT_EZ PF13513.6 ORY60375.1 - 1.5e-14 54.1 29.2 3.2e-08 33.9 0.3 10.3 6 2 3 10 10 10 4 HEAT-like repeat HEAT PF02985.22 ORY60375.1 - 9e-10 38.0 20.6 0.00017 21.5 0.1 9.5 11 0 0 11 11 8 2 HEAT repeat UME PF08064.13 ORY60375.1 - 3.3e-08 33.4 1.2 0.0035 17.2 0.1 5.7 4 1 0 4 4 4 1 UME (NUC010) domain HEAT_2 PF13646.6 ORY60375.1 - 4.6e-07 30.1 4.0 0.00014 22.1 0.5 7.8 6 3 3 9 9 9 3 HEAT repeats IFRD PF05004.13 ORY60375.1 - 4.7e-07 29.2 11.8 0.015 14.5 0.6 4.6 3 3 0 3 3 3 3 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.7 ORY60375.1 - 7.1e-06 26.1 0.2 0.0029 17.6 0.0 3.4 3 1 1 4 4 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY60375.1 - 1.6e-05 25.4 0.0 0.16 12.5 0.0 3.4 3 0 0 3 3 2 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 ORY60375.1 - 5.1e-05 23.1 0.6 0.001 18.9 0.1 3.5 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 ORY60375.1 - 0.0006 19.7 1.0 0.01 15.7 0.1 3.5 3 1 0 4 4 4 1 Importin-beta N-terminal domain MMS19_N PF14500.6 ORY60375.1 - 0.0028 17.3 3.0 0.54 9.8 0.1 4.3 2 2 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 ORY60375.1 - 0.0071 15.9 1.3 7.4 6.1 0.1 4.4 2 2 2 5 5 5 2 CLASP N terminal DUF3385 PF11865.8 ORY60375.1 - 0.0071 16.3 0.0 12 5.8 0.0 4.8 5 1 0 5 5 5 0 Domain of unknown function (DUF3385) Urb2 PF10441.9 ORY60375.1 - 0.024 14.6 0.2 2.3 8.1 0.1 3.3 2 0 0 2 2 2 0 Urb2/Npa2 family DUF3433 PF11915.8 ORY60375.1 - 0.028 14.9 0.8 4.6 7.8 0.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3433) Tti2 PF10521.9 ORY60375.1 - 0.048 13.2 0.1 1.9 7.9 0.0 3.5 3 2 1 4 4 4 0 Tti2 family Arm PF00514.23 ORY60375.1 - 0.053 13.6 0.1 0.053 13.6 0.1 4.8 7 0 0 7 7 6 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 ORY60375.1 - 0.14 12.5 0.0 5 7.5 0.0 3.5 4 0 0 4 4 3 0 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 ORY60375.1 - 0.23 11.6 2.7 5.6 7.2 0.0 4.4 5 1 1 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_C PF12460.8 ORY60375.1 - 0.85 8.7 13.6 4.3 6.4 1.0 4.9 4 2 2 6 6 6 0 RNAPII transcription regulator C-terminal PAP2 PF01569.21 ORY60376.1 - 1.9e-29 102.2 2.8 4e-29 101.1 2.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ORY60376.1 - 0.017 14.8 2.9 0.22 11.2 2.3 2.2 1 1 0 1 1 1 0 PAP2 superfamily Ac76 PF05814.11 ORY60376.1 - 0.22 11.5 0.1 1.1 9.3 0.0 1.9 2 0 0 2 2 2 0 Orf76 (Ac76) DUF456 PF04306.13 ORY60376.1 - 0.67 10.2 5.7 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) PAP2_C PF14360.6 ORY60376.1 - 4.4 7.9 6.7 0.45 11.1 1.8 1.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal rRNA_processing PF08524.11 ORY60377.1 - 3.5e-12 46.6 9.6 2e-06 27.9 0.8 2.2 2 0 0 2 2 2 2 rRNA processing TFIIF_alpha PF05793.12 ORY60377.1 - 0.031 12.9 7.2 0.04 12.5 7.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 ORY60377.1 - 1.2 7.3 3.4 1.3 7.2 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein F-box-like PF12937.7 ORY60379.1 - 0.00034 20.4 0.1 0.00065 19.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Fip1 PF05182.13 ORY60379.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Fip1 motif Hydrolase_4 PF12146.8 ORY60380.1 - 2.7e-19 69.4 0.0 4.2e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY60380.1 - 4.7e-18 65.7 0.1 2.2e-14 53.7 0.1 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY60380.1 - 1.4e-15 58.5 0.1 1.8e-15 58.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORY60380.1 - 5.6e-05 23.2 0.0 0.00016 21.7 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 ORY60380.1 - 0.00025 21.0 0.2 0.078 12.8 0.2 2.2 1 1 0 1 1 1 1 Serine hydrolase Esterase PF00756.20 ORY60380.1 - 0.0006 19.5 0.6 0.004 16.8 0.4 2.0 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ORY60380.1 - 0.0032 17.3 0.1 0.2 11.4 0.0 2.6 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase LIP PF03583.14 ORY60380.1 - 0.0064 15.9 0.8 0.062 12.6 0.3 2.0 2 0 0 2 2 2 1 Secretory lipase Thioesterase PF00975.20 ORY60380.1 - 0.029 14.5 0.1 0.056 13.5 0.1 1.5 1 0 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 ORY60380.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_4 PF08386.10 ORY60380.1 - 0.036 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 ORY60380.1 - 0.053 13.0 1.5 1.4 8.4 0.5 2.7 1 1 1 2 2 2 0 Esterase PHB depolymerase Lipase_3 PF01764.25 ORY60380.1 - 0.078 12.8 0.4 0.2 11.5 0.3 1.6 1 1 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.13 ORY60380.1 - 0.078 12.6 0.1 0.25 11.0 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 ORY60380.1 - 0.11 12.3 0.1 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family adh_short PF00106.25 ORY60381.1 - 1.2e-38 132.6 0.1 1.5e-38 132.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY60381.1 - 6.6e-32 110.9 0.1 8.9e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY60381.1 - 0.0056 16.6 0.3 0.0084 16.0 0.3 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 ORY60381.1 - 0.045 14.5 0.0 0.088 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 ORY60382.1 - 1.2e-05 25.3 8.0 2.4e-05 24.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY60382.1 - 1.3e-05 24.4 0.5 1.9e-05 23.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran_CTD PF16326.5 ORY60382.1 - 0.16 12.2 0.2 0.31 11.3 0.2 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain PhyH PF05721.13 ORY60383.1 - 3.2e-05 24.3 0.1 6.9e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ORY60383.1 - 0.00039 19.3 0.0 0.75 8.5 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ORY60383.1 - 0.027 14.9 0.0 0.056 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 ORY60383.1 - 0.031 15.2 0.0 0.069 14.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 ORY60384.1 - 4.3e-35 121.3 31.9 4.3e-35 121.3 31.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Rpp20 PF12328.8 ORY60385.1 - 1.7e-05 24.8 0.7 0.00014 21.9 0.7 1.9 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P UPF0254 PF06787.11 ORY60385.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) IF-2 PF11987.8 ORY60386.1 - 5.5e-26 90.7 0.2 1.4e-25 89.4 0.2 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 ORY60386.1 - 4.2e-23 81.9 0.0 7.3e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Peptidase_S8 PF00082.22 ORY60387.1 - 1.2e-42 146.3 2.1 1.8e-42 145.6 2.1 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY60387.1 - 5e-11 43.3 0.8 8.2e-11 42.6 0.3 1.7 2 0 0 2 2 2 1 Fn3-like domain DUF11 PF01345.18 ORY60387.1 - 0.0037 17.5 1.0 0.026 14.8 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF11 CaATP_NAI PF12515.8 ORY60389.1 - 0.26 11.0 4.9 0.1 12.3 2.2 1.8 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Rpp20 PF12328.8 ORY60390.1 - 0.014 15.3 0.1 0.049 13.6 0.1 1.8 1 1 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P SSB PF00436.25 ORY60391.1 - 1.2e-15 57.4 0.0 1.5e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PhzC-PhzF PF02567.16 ORY60393.1 - 5.7e-25 88.3 0.0 2.7e-24 86.1 0.0 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein adh_short PF00106.25 ORY60394.1 - 4.1e-25 88.4 0.0 8e-22 77.7 0.0 2.3 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY60394.1 - 2.4e-15 56.8 0.0 2.4e-14 53.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY60394.1 - 1.3e-07 31.7 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY60394.1 - 0.0082 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein YccV-like PF08755.11 ORY60395.1 - 1.1e-21 77.1 0.1 2.8e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 ORY60395.1 - 1.5e-14 53.8 0.0 2.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 ORY60395.1 - 5.6e-06 26.1 1.3 5.6e-06 26.1 1.3 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY60395.1 - 1.1e-05 25.1 0.3 4.3e-05 23.3 0.3 2.0 1 0 0 1 1 1 1 F-box domain TauD PF02668.16 ORY60396.1 - 7.2e-29 101.4 0.1 1.9e-28 100.1 0.1 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PhyH PF05721.13 ORY60396.1 - 0.041 14.1 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) TauD PF02668.16 ORY60397.1 - 7.8e-30 104.6 0.0 1.9e-29 103.3 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transp_cyt_pur PF02133.15 ORY60398.1 - 1.2e-97 327.5 34.2 1.4e-97 327.3 34.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RRM_1 PF00076.22 ORY60399.1 - 3.9e-15 55.4 0.0 5.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3602 PF12223.8 ORY60399.1 - 0.17 12.5 4.8 0.36 11.5 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) zf-MYND PF01753.18 ORY60400.1 - 1.7e-09 37.6 9.3 2.9e-09 36.9 9.3 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY60400.1 - 1.3 9.3 7.8 3.6 8.0 7.8 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding CHRD PF07452.12 ORY60401.1 - 2.4e-13 51.1 0.0 3.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 CHRD domain Phosducin PF02114.16 ORY60404.1 - 2.5e-10 39.7 0.1 6.5e-10 38.4 0.1 1.6 2 0 0 2 2 2 1 Phosducin Thioredoxin PF00085.20 ORY60404.1 - 0.004 17.1 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin PRCC PF10253.9 ORY60405.1 - 2.4e-23 84.1 3.7 2.4e-23 84.1 3.7 2.5 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting P5CR_dimer PF14748.6 ORY60406.1 - 4.5e-38 129.6 3.6 5e-38 129.5 2.6 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORY60406.1 - 9.6e-09 35.7 0.0 2.4e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_28_C PF04101.16 ORY60409.1 - 2.6e-13 50.3 0.0 4e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Myb_DNA-bind_7 PF15963.5 ORY60410.1 - 1.5e-25 88.9 0.2 1.5e-25 88.9 0.2 2.3 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORY60410.1 - 1.5e-10 41.1 0.1 1.5e-10 41.1 0.1 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY60410.1 - 4.6e-06 26.8 0.3 1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY60410.1 - 0.056 13.6 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 UvrB PF12344.8 ORY60410.1 - 0.07 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 Ultra-violet resistance protein B DUF2040 PF09745.9 ORY60411.1 - 1.4e-36 125.2 18.2 1.4e-36 125.2 18.2 2.8 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) DUF2315 PF10231.9 ORY60411.1 - 0.042 14.0 0.7 0.042 14.0 0.7 2.5 2 1 0 2 2 2 0 Apoptogenic protein 1 Rib_5-P_isom_A PF06026.14 ORY60412.1 - 1.5e-38 132.1 0.0 1.9e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) mRNA_triPase PF02940.15 ORY61043.1 - 3e-32 112.1 0.0 3.7e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain DUF2156 PF09924.9 ORY61044.1 - 5.4e-18 65.0 0.1 6.7e-18 64.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Acetyltransf_10 PF13673.7 ORY61044.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 ORY61044.1 - 0.042 14.0 0.3 0.16 12.1 0.3 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.13 ORY61045.1 - 2.3e-23 83.2 0.0 3e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY61045.1 - 0.0011 17.9 0.0 0.051 12.4 0.0 2.2 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ORY61045.1 - 0.052 12.8 0.0 0.091 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY61045.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 ORY61045.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF2235 PF09994.9 ORY61045.1 - 0.2 11.0 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_6 PF12697.7 ORY61045.1 - 0.39 11.3 6.3 0.093 13.3 2.6 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase family Histone PF00125.24 ORY61046.1 - 4.9e-33 114.3 0.1 3e-32 111.7 0.1 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY61046.1 - 0.0024 17.9 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 ORY61046.1 - 0.012 15.6 0.1 0.032 14.3 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 ORY61046.1 - 0.032 14.6 0.0 0.046 14.1 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORY61046.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 ORY61046.1 - 0.13 12.9 1.1 0.17 12.5 1.1 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Zn_clus PF00172.18 ORY61047.1 - 2.2e-08 34.1 7.5 3.6e-08 33.4 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY61047.1 - 1.5e-06 27.5 0.6 3.2e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DAO PF01266.24 ORY61048.1 - 1.6e-39 136.5 0.2 1.8e-39 136.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY61048.1 - 5.9e-08 32.8 0.2 2.3e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ThiF PF00899.21 ORY61048.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.24 ORY61048.1 - 0.00018 20.7 2.1 0.0063 15.7 0.1 2.7 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 ORY61048.1 - 0.00033 20.0 0.0 0.00061 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ORY61048.1 - 0.0019 17.4 0.0 0.075 12.1 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY61048.1 - 0.0019 18.7 0.0 0.024 15.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY61048.1 - 0.002 18.4 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 ORY61048.1 - 0.0035 16.6 0.0 0.068 12.4 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 ORY61048.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus GMC_oxred_N PF00732.19 ORY61048.1 - 0.0065 15.9 0.1 0.83 9.0 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Thi4 PF01946.17 ORY61048.1 - 0.011 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 ORY61048.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY61048.1 - 0.015 14.0 0.2 0.43 9.2 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein Sacchrp_dh_NADP PF03435.18 ORY61048.1 - 0.032 14.5 0.0 0.061 13.6 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY61048.1 - 0.036 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 ORY61048.1 - 0.045 14.6 0.0 10 7.0 0.0 2.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 ORY61048.1 - 0.064 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 ORY61048.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.6 ORY61048.1 - 0.076 13.0 0.1 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 ORY61048.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY61048.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 2 0 0 2 2 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-H2C2_2 PF13465.6 ORY61049.1 - 2.6e-07 30.7 0.4 2.6e-07 30.7 0.4 2.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY61049.1 - 2e-05 24.8 12.9 0.0021 18.4 0.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY61049.1 - 0.00023 21.7 12.8 0.09 13.7 7.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger CpXC PF14353.6 ORY61049.1 - 0.0064 16.5 0.4 0.0081 16.2 0.4 1.2 1 0 0 1 1 1 1 CpXC protein Rtf2 PF04641.12 ORY61049.1 - 0.045 13.1 0.2 0.052 12.9 0.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C2H2_jaz PF12171.8 ORY61049.1 - 0.16 12.3 10.5 0.78 10.1 0.7 2.5 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY61049.1 - 6.4 7.3 11.5 0.93 10.0 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MFS_1 PF07690.16 ORY61050.1 - 0.0016 17.4 8.6 0.002 17.1 8.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY61050.1 - 0.003 16.9 0.7 0.0038 16.6 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 ORY61051.1 - 8.3e-23 80.9 37.7 1.5e-22 80.0 34.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY61051.1 - 0.0032 16.8 7.8 0.0032 16.8 7.8 2.8 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB DUF3084 PF11283.8 ORY61051.1 - 0.063 13.3 2.7 0.3 11.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3084) Pam17 PF08566.10 ORY61051.1 - 0.59 10.0 2.1 6.6 6.6 0.3 3.0 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 Hydantoinase_B PF02538.14 ORY61052.1 - 1.8e-179 597.5 0.6 2.5e-179 597.0 0.6 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORY61052.1 - 3.7e-103 344.8 0.7 5.5e-103 344.2 0.1 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY61052.1 - 1.7e-60 203.7 0.2 7.3e-59 198.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 ORY61053.1 - 6.8e-11 41.7 10.6 2.8e-09 36.4 1.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Holin_SPP1 PF04688.13 ORY61053.1 - 0.14 12.3 0.3 0.51 10.5 0.3 1.9 1 0 0 1 1 1 0 SPP1 phage holin Fungal_trans PF04082.18 ORY61054.1 - 8.4e-19 67.6 0.0 1.2e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEC-1_N PF04625.13 ORY61054.1 - 1.8 7.5 7.4 3.3 6.6 7.4 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Zn_clus PF00172.18 ORY61055.1 - 1.2e-08 35.0 9.3 2e-08 34.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY61055.1 - 0.05 12.6 1.0 0.14 11.1 1.0 1.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain Pkinase PF00069.25 ORY61056.1 - 4e-61 206.7 0.0 6.4e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY61056.1 - 1.6e-36 125.9 0.0 2.2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY61056.1 - 0.0013 17.6 2.3 0.016 14.0 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 ORY61056.1 - 0.15 11.3 0.0 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 ORY61056.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 ORY61056.1 - 1.9 7.4 6.7 0.14 11.0 0.2 2.3 2 1 0 2 2 2 0 Haspin like kinase domain Pol_alpha_B_N PF08418.10 ORY61056.1 - 2.4 8.1 13.7 0.096 12.6 0.6 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Apt1 PF10351.9 ORY61056.1 - 5.9 5.6 13.8 0.66 8.8 2.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Fungal_trans PF04082.18 ORY61057.1 - 2.8e-14 52.8 0.0 5.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY61057.1 - 3.2e-07 30.3 2.5 5.9e-07 29.5 2.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_6 PF12774.7 ORY61057.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Alpha-L-AF_C PF06964.12 ORY61058.1 - 1.9e-28 99.7 0.0 2.8e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Fungal_trans PF04082.18 ORY61059.1 - 1.9e-08 33.7 0.0 4.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY61059.1 - 1.9e-07 31.1 3.7 4.2e-07 30.0 3.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 ORY61060.1 - 7.6e-89 298.6 28.6 8.9e-89 298.4 28.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter PRA1 PF03208.19 ORY61060.1 - 1.4 8.6 9.2 5.8 6.5 9.2 2.1 1 0 0 1 1 1 0 PRA1 family protein DUF2621 PF11084.8 ORY61060.1 - 3.7 7.5 4.2 7.6 6.5 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Cellulase PF00150.18 ORY61061.1 - 1.9e-30 106.3 0.5 3.4e-30 105.4 0.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 ORY61061.1 - 0.005 16.2 0.0 0.78 9.0 0.1 3.0 1 1 1 2 2 2 1 Beta-galactosidase Bac_rhamnosid6H PF17389.2 ORY61062.1 - 6.5e-15 55.2 0.0 8.6e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_45 PF02015.16 ORY61062.1 - 0.16 11.9 0.2 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 45 Sugar_tr PF00083.24 ORY61063.1 - 7.3e-74 249.2 17.6 8.5e-74 249.0 17.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY61063.1 - 5.9e-20 71.5 33.9 6e-20 71.5 25.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY61063.1 - 0.0022 16.5 3.5 0.0022 16.5 3.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 ORY61063.1 - 0.28 10.0 13.8 2.1 7.1 5.0 2.6 2 1 0 2 2 2 0 MFS_1 like family ABC2_membrane PF01061.24 ORY61064.1 - 7e-44 149.8 14.8 1.4e-43 148.8 14.8 1.4 1 0 0 1 1 1 1 ABC-2 type transporter Fungal_trans PF04082.18 ORY61064.1 - 1.3e-19 70.3 1.0 1.2e-18 67.1 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cupin_2 PF07883.11 ORY61064.1 - 6e-13 48.3 0.0 9.9e-09 34.8 0.1 2.6 2 0 0 2 2 2 2 Cupin domain Zn_clus PF00172.18 ORY61064.1 - 9e-07 28.9 16.0 1.6e-06 28.1 16.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AraC_binding PF02311.19 ORY61064.1 - 0.00032 20.6 0.0 0.00091 19.1 0.0 1.7 1 0 0 1 1 1 1 AraC-like ligand binding domain ABC_tran PF00005.27 ORY61064.1 - 0.00077 20.0 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Cupin_3 PF05899.12 ORY61064.1 - 0.016 14.9 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Abhydrolase_3 PF07859.13 ORY61065.1 - 4.4e-10 39.8 0.1 6.7e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY61065.1 - 1e-07 31.3 0.0 1.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 ORY61065.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Lipase PF00151.19 ORY61065.1 - 0.23 10.7 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Lipase Glyco_hydro_106 PF17132.4 ORY61066.1 - 4.9e-37 127.6 0.0 1.1e-29 103.3 0.0 2.3 2 0 0 2 2 2 2 alpha-L-rhamnosidase Flexi_CP_N PF08358.10 ORY61066.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 2 0 0 2 2 2 0 Carlavirus coat Sugar_tr PF00083.24 ORY61067.1 - 4.6e-55 187.3 17.5 5.3e-55 187.1 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY61067.1 - 2.3e-14 53.1 35.1 2.3e-14 53.1 35.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ORY61067.1 - 1 7.6 7.1 1.7 6.9 4.6 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_3_C PF01915.22 ORY61068.1 - 4e-46 157.6 0.0 7.8e-46 156.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY61068.1 - 6.9e-30 104.5 0.0 1.2e-29 103.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY61068.1 - 2.1e-20 72.6 0.1 4.9e-20 71.4 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar_tr PF00083.24 ORY61069.1 - 2.4e-58 198.1 21.8 2.8e-58 197.9 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY61069.1 - 2.5e-15 56.3 28.3 2.5e-15 56.3 28.3 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 ORY61070.1 - 2.2e-89 298.4 53.5 6e-48 163.0 19.3 2.6 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 ORY61070.1 - 2.4e-36 123.5 6.2 1.3e-31 108.3 0.1 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 ORY61070.1 - 2.9e-36 125.0 0.0 6.7e-17 62.3 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.6 ORY61070.1 - 2.4e-18 66.5 0.1 6.4e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 ORY61070.1 - 6.2e-06 25.9 0.3 0.00012 21.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ORY61070.1 - 1.2e-05 25.8 0.2 0.01 16.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 ORY61070.1 - 2e-05 24.8 0.1 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY61070.1 - 0.00012 22.0 0.2 0.0056 16.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY61070.1 - 0.00019 21.1 0.8 0.03 14.1 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY61070.1 - 0.00029 21.4 0.0 0.026 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY61070.1 - 0.0012 18.6 0.4 0.27 10.9 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY61070.1 - 0.0038 17.5 0.3 2 8.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 ORY61070.1 - 0.0088 15.5 0.0 1.2 8.5 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY61070.1 - 0.015 15.1 0.3 3.1 7.5 0.1 2.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 ORY61070.1 - 0.028 14.8 3.6 1.6 9.2 0.0 3.1 3 1 0 3 3 3 0 AAA domain NACHT PF05729.12 ORY61070.1 - 0.03 14.2 0.9 2.8 7.9 0.3 2.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 ORY61070.1 - 0.039 14.4 0.9 8.2 6.9 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY61070.1 - 0.097 12.6 0.0 4.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Ploopntkinase3 PF18751.1 ORY61070.1 - 0.13 12.2 0.2 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF5455 PF17537.2 ORY61070.1 - 0.16 12.4 6.0 15 6.1 4.5 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5455) NTPase_1 PF03266.15 ORY61070.1 - 0.23 11.4 0.6 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 NTPase cobW PF02492.19 ORY61070.1 - 0.32 10.6 1.3 2.5 7.6 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Kelch_5 PF13854.6 ORY61071.1 - 2.3e-31 107.2 11.0 1.9e-06 27.7 0.4 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 ORY61071.1 - 1.1e-26 92.2 11.0 1.4e-09 37.4 2.9 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ORY61071.1 - 3.3e-26 91.0 13.5 3.5e-08 33.5 0.4 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY61071.1 - 4.3e-26 90.3 12.2 7.8e-08 32.3 1.5 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 ORY61071.1 - 1.3e-25 89.1 18.2 1.2e-05 25.2 0.0 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY61071.1 - 8.2e-23 79.5 10.9 0.0028 17.6 0.0 6.7 6 0 0 6 6 6 5 Kelch motif RAG2 PF03089.14 ORY61071.1 - 0.022 13.8 0.5 22 3.9 0.0 4.1 3 1 2 5 5 5 0 Recombination activating protein 2 HTH_34 PF13601.6 ORY61071.1 - 0.052 13.7 0.6 0.18 12.0 0.6 1.9 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_20 PF12840.7 ORY61071.1 - 0.38 10.8 6.0 0.19 11.8 0.5 3.4 3 0 0 3 3 3 0 Helix-turn-helix domain TAF1D PF15333.6 ORY61151.1 - 0.31 10.8 2.5 0.72 9.5 2.5 1.6 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D IFT43 PF15305.6 ORY61151.1 - 0.43 10.8 6.9 1.1 9.5 6.9 1.6 1 0 0 1 1 1 0 Intraflagellar transport protein 43 BSP_II PF05432.11 ORY61151.1 - 0.72 9.5 16.0 0.18 11.4 2.0 2.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PIG-L PF02585.17 ORY61152.1 - 0.0001 22.9 0.0 0.00014 22.5 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase F5_F8_type_C PF00754.25 ORY61153.1 - 4.1e-17 62.5 16.0 1e-05 25.7 1.4 4.9 4 0 0 4 4 4 4 F5/8 type C domain PIG-L PF02585.17 ORY61153.1 - 4.9e-11 43.4 0.0 1.1e-10 42.3 0.0 1.6 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HtrL_YibB PF09612.10 ORY61155.1 - 3.2e-05 23.6 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Nuc_sug_transp PF04142.15 ORY61156.1 - 6.9e-69 232.4 21.2 3.3e-61 207.2 19.4 3.8 2 1 0 2 2 2 2 Nucleotide-sugar transporter Exostosin PF03016.15 ORY61156.1 - 2e-17 63.4 0.0 6.3e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Exostosin family UAA PF08449.11 ORY61156.1 - 4.5e-05 22.8 8.8 0.00081 18.7 0.5 2.3 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 ORY61156.1 - 0.0002 21.5 0.9 0.0002 21.5 0.9 4.2 5 0 0 5 5 5 2 EamA-like transporter family DUF2226 PF09987.9 ORY61158.1 - 0.051 12.9 0.0 0.059 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Glyoxal_oxid_N PF07250.11 ORY61159.1 - 2.7e-36 125.0 0.6 1.6e-25 89.7 0.2 4.3 3 2 1 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY61159.1 - 2e-25 88.9 0.0 5e-25 87.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 ORY61159.1 - 0.98 9.5 6.0 4 7.5 0.1 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Serglycin PF04360.12 ORY61159.1 - 1.5 8.8 4.0 3.1 7.8 4.0 1.5 1 0 0 1 1 1 0 Serglycin Cyt-b5 PF00173.28 ORY61160.1 - 7.1e-19 67.7 0.0 1e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MDM31_MDM32 PF08118.11 ORY61161.1 - 1.2e-188 628.1 0.0 1.6e-188 627.7 0.0 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Mo-co_dimer PF03404.16 ORY61161.1 - 0.1 12.6 0.6 0.28 11.2 0.1 1.9 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain TruB_N PF01509.18 ORY61162.1 - 1.3e-41 142.4 0.0 1e-40 139.6 0.0 2.1 1 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ORY61162.1 - 7.4e-07 29.2 0.0 5.6e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain HAD_2 PF13419.6 ORY61163.1 - 1.1e-17 64.7 0.0 3.7e-17 63.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY61163.1 - 9.8e-16 58.7 0.0 2.3e-15 57.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY61163.1 - 5.3e-05 23.7 0.0 0.00012 22.6 0.0 1.6 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY61163.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ORY61163.1 - 0.013 15.6 0.0 6.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HA2 PF04408.23 ORY61164.1 - 5.9e-26 90.9 0.9 2.7e-25 88.7 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY61164.1 - 1.4e-18 67.0 0.0 3.3e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY61164.1 - 1.1e-12 48.3 0.0 1.4e-10 41.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY61164.1 - 7.1e-09 35.7 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY61164.1 - 3.7e-05 24.0 0.0 0.00033 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORY61164.1 - 0.00089 19.3 0.0 0.027 14.5 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATPase PF06745.13 ORY61164.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 ORY61164.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nop25 PF09805.9 ORY61164.1 - 0.018 15.5 18.3 0.66 10.4 8.9 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) T2SSE PF00437.20 ORY61164.1 - 0.022 13.9 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 ORY61164.1 - 0.051 14.1 0.5 0.18 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY61164.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY61164.1 - 0.099 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein BUD22 PF09073.10 ORY61164.1 - 4.2 6.6 30.3 0.69 9.2 7.4 2.2 2 0 0 2 2 2 0 BUD22 DUF1499 PF07386.11 ORY61165.1 - 0.094 13.3 1.5 0.16 12.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) AC_N PF16214.5 ORY61165.1 - 0.29 10.2 4.2 0.38 9.8 4.2 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region NB-ARC PF00931.22 ORY61166.1 - 2.3e-10 40.1 0.0 3.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 ORY61166.1 - 4.8e-07 29.8 0.1 1.8e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 ORY61166.1 - 0.00035 21.0 3.1 0.00035 21.0 3.1 3.9 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 ORY61166.1 - 0.011 16.0 0.0 0.039 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORY61166.1 - 0.11 12.5 1.1 2.1 8.4 0.2 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 ORY61166.1 - 0.28 10.7 3.1 2.5 7.6 1.0 2.7 2 1 0 2 2 2 0 AAA domain ADH_zinc_N_2 PF13602.6 ORY61168.1 - 4.2e-13 50.5 0.0 6.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY61168.1 - 0.001 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YjeF_N PF03853.15 ORY61168.1 - 0.0031 17.4 0.0 0.0047 16.8 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus THDPS_N_2 PF14805.6 ORY61168.1 - 0.16 12.2 0.4 0.32 11.2 0.4 1.5 1 1 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Sec10 PF07393.11 ORY61169.1 - 3.6e-223 743.0 0.0 4.5e-223 742.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Acetyltransf_1 PF00583.25 ORY61170.1 - 2e-13 50.6 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY61170.1 - 3.1e-12 46.5 0.3 3.6e-12 46.3 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY61170.1 - 8.2e-08 32.6 0.0 1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY61170.1 - 1.6e-06 28.0 0.1 2.4e-06 27.4 0.1 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY61170.1 - 0.0069 16.5 0.2 0.015 15.4 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY61170.1 - 0.1 12.1 1.3 0.13 11.8 0.2 1.6 2 0 0 2 2 2 0 Putative acetyl-transferase AIM3 PF17096.5 ORY61171.1 - 0.1 13.6 8.2 2.4 9.2 1.0 2.6 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 RXT2_N PF08595.11 ORY61171.1 - 1.2 9.2 6.6 3.3 7.7 1.4 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleo_P87 PF07267.11 ORY61171.1 - 4.9 5.9 5.6 5.7 5.7 0.8 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 ORY61171.1 - 6.8 6.4 9.1 2.2 7.9 0.9 2.3 2 0 0 2 2 2 0 FAM176 family RNase_PH PF01138.21 ORY61172.1 - 3.9e-19 69.4 0.0 5.9e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY61172.1 - 9.5e-07 28.8 0.0 2.7e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 SMC_N PF02463.19 ORY61173.1 - 3.7e-21 75.6 0.0 6.1e-21 74.9 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY61173.1 - 2.3e-16 60.9 2.3 2.3e-16 60.9 2.3 5.5 3 2 1 4 4 3 1 AAA domain AAA_15 PF13175.6 ORY61173.1 - 8.4e-09 35.6 4.0 8.4e-09 35.6 4.0 3.5 2 2 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 ORY61173.1 - 0.00022 21.2 0.4 0.0026 17.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF1664 PF07889.12 ORY61173.1 - 0.0017 18.4 5.0 0.0017 18.4 5.0 5.3 4 1 0 5 5 5 1 Protein of unknown function (DUF1664) AAA_29 PF13555.6 ORY61173.1 - 0.0018 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 ORY61173.1 - 0.0029 18.0 0.1 0.07 13.6 0.1 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Med4 PF10018.9 ORY61173.1 - 0.004 16.9 2.6 0.004 16.9 2.6 6.2 4 2 1 7 7 6 1 Vitamin-D-receptor interacting Mediator subunit 4 DASH_Duo1 PF08651.10 ORY61173.1 - 0.063 13.1 4.8 3.7 7.4 0.1 3.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 Nipped-B_C PF12830.7 ORY61173.1 - 0.15 11.9 6.6 0.091 12.7 2.5 2.5 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus ABC_tran PF00005.27 ORY61173.1 - 0.22 12.1 0.1 0.22 12.1 0.1 5.1 3 2 0 3 3 2 0 ABC transporter AAA_18 PF13238.6 ORY61173.1 - 8.7 6.9 12.4 0.14 12.7 0.7 4.0 3 3 0 3 3 3 0 AAA domain fn3_2 PF16893.5 ORY61174.1 - 3.7e-37 126.3 0.8 6.3e-37 125.6 0.8 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 ORY61174.1 - 5.1e-23 80.8 0.2 9e-23 80.0 0.2 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 ORY61174.1 - 1.1e-06 28.9 0.0 2.7e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 ORY61174.1 - 0.00012 22.4 0.1 0.00029 21.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 ORY61174.1 - 0.00022 21.5 0.0 0.00056 20.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 ORY61174.1 - 0.00065 19.6 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 ORY61174.1 - 0.0018 18.4 0.0 0.0073 16.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_3 PF18428.1 ORY61174.1 - 0.0038 17.3 0.0 0.0091 16.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Phage_holin_3_2 PF04550.12 ORY61174.1 - 0.15 12.6 0.1 0.28 11.8 0.1 1.3 1 0 0 1 1 1 0 Phage holin family 2 BTB PF00651.31 ORY61175.1 - 0.0053 17.0 0.0 0.0077 16.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain XG_FTase PF03254.13 ORY61176.1 - 2.5e-06 26.4 0.1 0.00014 20.7 0.0 2.1 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase NodZ PF05830.11 ORY61176.1 - 0.017 13.9 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) PTR2 PF00854.21 ORY61177.1 - 2.3e-22 79.4 3.6 2.6e-22 79.2 3.6 1.0 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 ORY61177.1 - 0.0011 18.0 6.6 0.0016 17.4 6.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY61177.1 - 0.0081 15.1 5.4 0.023 13.6 5.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter BTB PF00651.31 ORY61178.1 - 0.00024 21.3 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain CTP_transf_like PF01467.26 ORY61179.1 - 1.5e-06 28.4 0.0 1.5e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1_ass PF16581.5 ORY61179.1 - 0.0078 16.2 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Cytidyltransferase-related C-terminal region Citrate_ly_lig PF08218.11 ORY61179.1 - 0.045 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain TCTP PF00838.17 ORY61180.1 - 1.3e-71 240.3 2.1 1.4e-71 240.2 2.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Nse4-Nse3_bdg PF15412.6 ORY61180.1 - 0.08 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE RAG1 PF12940.7 ORY61181.1 - 0.074 11.1 0.0 0.15 10.1 0.0 1.4 2 0 0 2 2 2 0 Recombination-activation protein 1 (RAG1), recombinase Abhydrolase_6 PF12697.7 ORY61182.1 - 6.5e-09 36.7 0.3 1e-08 36.0 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY61182.1 - 2.1e-08 34.1 0.0 2.7e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY61182.1 - 0.0017 17.7 0.0 0.037 13.3 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY61182.1 - 0.1 12.0 0.1 1.8 8.0 0.0 2.4 3 0 0 3 3 3 0 Prolyl oligopeptidase family RRM_1 PF00076.22 ORY61183.1 - 2.4e-25 88.1 0.0 1.4e-17 63.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY61183.1 - 0.0021 17.9 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif YflT PF11181.8 ORY61183.1 - 0.0094 16.4 0.5 0.27 11.8 0.1 2.1 2 0 0 2 2 2 1 Heat induced stress protein YflT DbpA PF03880.15 ORY61183.1 - 0.025 14.5 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_3 PF08777.11 ORY61183.1 - 0.037 14.1 0.0 0.23 11.5 0.0 2.0 1 1 1 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 ORY61183.1 - 0.15 12.1 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Aldedh PF00171.22 ORY61185.1 - 2.8e-159 530.5 4.6 3.1e-159 530.4 4.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CO_deh_flav_C PF03450.17 ORY61185.1 - 0.11 12.7 0.3 8.5 6.6 0.0 3.4 3 0 0 3 3 3 0 CO dehydrogenase flavoprotein C-terminal domain Wtap PF17098.5 ORY61185.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family Malic_M PF03949.15 ORY61186.1 - 2.3e-89 299.1 0.0 3.1e-89 298.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORY61186.1 - 5.2e-63 212.1 0.0 7.4e-63 211.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain LRR_4 PF12799.7 ORY61188.1 - 7e-12 45.4 8.0 0.07 13.6 0.0 7.7 5 3 2 8 8 8 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY61188.1 - 1.1e-11 44.5 3.1 1.1e-11 44.5 3.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 ORY61188.1 - 2.5e-11 42.7 12.6 0.04 14.0 0.0 10.4 11 0 0 11 11 11 3 Leucine Rich repeat F-box PF00646.33 ORY61188.1 - 0.00026 20.8 1.4 0.00026 20.8 1.4 3.2 3 0 0 3 3 3 1 F-box domain SAM_Ste50p PF09235.10 ORY61188.1 - 0.002 18.3 1.8 46 4.3 0.0 5.0 5 0 0 5 5 5 0 Ste50p, sterile alpha motif F-box_4 PF15966.5 ORY61188.1 - 0.032 14.1 1.0 0.66 9.9 0.1 2.7 2 0 0 2 2 2 0 F-box LRR_8 PF13855.6 ORY61188.1 - 0.11 12.3 7.9 3.8 7.3 0.2 5.5 6 2 1 7 7 7 0 Leucine rich repeat LRR_1 PF00560.33 ORY61188.1 - 0.5 11.1 11.2 1.3e+02 3.8 0.0 7.1 8 0 0 8 8 8 0 Leucine Rich Repeat RSN1_7TM PF02714.15 ORY61189.1 - 1.2e-05 24.8 12.3 1.7e-05 24.3 12.3 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 ORY61189.1 - 0.075 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter MoCF_biosynth PF00994.24 ORY61190.1 - 1.7e-34 118.5 0.0 2.8e-34 117.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain CBM_1 PF00734.18 ORY61191.1 - 2.9e-09 36.7 10.6 2.9e-09 36.7 10.6 6.5 10 0 0 10 10 10 1 Fungal cellulose binding domain Granulin PF00396.18 ORY61191.1 - 0.19 12.1 5.8 4 7.9 2.0 3.1 2 0 0 2 2 2 0 Granulin DUF971 PF06155.12 ORY61191.1 - 0.38 11.4 3.0 1.7e+02 3.0 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF971) Mito_carr PF00153.27 ORY61192.1 - 1.2e-49 166.1 5.4 3.6e-17 62.1 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ada3 PF10198.9 ORY61905.1 - 3.7e-29 101.5 2.1 3.7e-29 101.5 2.1 2.9 2 1 1 3 3 3 1 Histone acetyltransferases subunit 3 MgtE PF01769.16 ORY61906.1 - 1.4e-39 135.3 17.0 1.4e-21 77.1 0.3 4.0 3 1 1 4 4 4 2 Divalent cation transporter DUF1676 PF07898.13 ORY61906.1 - 3.7 7.5 6.3 11 6.0 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) PAP2 PF01569.21 ORY61907.1 - 2.3e-21 76.0 4.8 2.3e-21 76.0 4.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF2530 PF10745.9 ORY61907.1 - 0.013 15.7 4.2 3.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Tom37 PF10568.9 ORY61908.1 - 3.4e-22 79.1 0.2 6.1e-22 78.3 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 ORY61908.1 - 3.1e-09 37.5 0.0 5.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 ORY61908.1 - 3e-07 30.1 0.1 6.6e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NCA2 PF08637.10 ORY61909.1 - 3.5e-83 279.1 0.0 5.3e-83 278.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 RRM_1 PF00076.22 ORY61910.1 - 1.5e-24 85.5 0.0 8.5e-06 25.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY61910.1 - 0.00011 21.8 0.0 0.0088 15.6 0.0 3.3 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N PF08240.12 ORY61911.1 - 1.6e-22 79.4 1.2 3.2e-22 78.5 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY61911.1 - 1.5e-15 57.3 0.1 2.4e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY61911.1 - 0.0048 16.4 1.1 0.069 12.6 1.1 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus 3HCDH PF00725.22 ORY61911.1 - 0.16 12.6 0.0 1.8 9.2 0.0 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain HA2 PF04408.23 ORY61913.1 - 1.2e-20 73.8 0.0 2.6e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY61913.1 - 2.1e-17 63.3 0.0 2.6e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY61913.1 - 1.9e-13 50.7 0.0 3.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY61913.1 - 1.1e-05 25.2 0.0 3.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY61913.1 - 2.3e-05 24.2 0.0 3.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain RVP_2 PF08284.11 ORY61913.1 - 0.00057 19.7 0.0 0.99 9.2 0.0 4.2 4 0 0 4 4 4 1 Retroviral aspartyl protease AAA_22 PF13401.6 ORY61913.1 - 0.0075 16.5 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY61913.1 - 0.17 12.2 0.0 0.53 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.25 ORY61914.1 - 5.6e-64 216.3 0.0 7e-64 215.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_M41 PF01434.18 ORY61915.1 - 1.5e-57 194.6 0.2 2.2e-57 194.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORY61915.1 - 7.3e-44 149.4 0.0 1.1e-42 145.6 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY61915.1 - 2.2e-09 37.0 0.0 5.5e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY61915.1 - 1.5e-05 24.8 0.0 0.00032 20.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY61915.1 - 2.2e-05 24.9 4.8 0.0019 18.6 0.2 4.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 ORY61915.1 - 0.00021 21.6 0.1 0.056 13.7 0.1 2.8 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 ORY61915.1 - 0.00053 19.3 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 ORY61915.1 - 0.00072 19.6 0.0 0.0029 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ORY61915.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 ORY61915.1 - 0.011 16.2 0.0 0.045 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY61915.1 - 0.02 15.1 0.0 0.07 13.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 ORY61915.1 - 0.033 14.4 0.0 0.086 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORY61915.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 ORY61915.1 - 0.072 12.5 0.1 0.072 12.5 0.1 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORY61915.1 - 0.12 11.9 0.5 1.2 8.7 0.3 2.3 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ORY61915.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY61915.1 - 0.21 10.9 0.0 0.44 9.9 0.0 1.4 1 0 0 1 1 1 0 KaiC zf-MYND PF01753.18 ORY61916.1 - 1.4e-09 37.9 9.1 3.1e-09 36.8 9.1 1.6 1 1 0 1 1 1 1 MYND finger Ank_4 PF13637.6 ORY61916.1 - 6.3e-08 33.0 0.1 0.12 13.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY61916.1 - 0.0033 17.7 0.0 5 7.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) zf-C6H2 PF15801.5 ORY61916.1 - 0.0095 16.2 0.7 0.0095 16.2 0.7 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Torus PF16131.5 ORY61917.1 - 1e-08 35.8 0.1 2.2e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 ORY61917.1 - 1e-05 25.4 3.7 1e-05 25.4 3.7 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 ORY61917.1 - 0.0003 20.6 2.4 0.0003 20.6 2.4 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 ORY61917.1 - 0.0042 17.3 0.1 0.0042 17.3 0.1 1.8 2 1 0 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 ORY61917.1 - 0.0047 16.7 3.4 0.0099 15.7 3.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger RRM_occluded PF16842.5 ORY61917.1 - 0.0065 16.3 0.0 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 ORY61917.1 - 0.027 14.3 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.6 ORY61917.1 - 0.028 14.9 1.8 0.028 14.9 1.8 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger FlgM PF04316.13 ORY61918.1 - 0.25 11.7 1.5 0.84 10.0 0.8 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Fungal_trans PF04082.18 ORY61919.1 - 2.3e-10 39.9 0.8 3.4e-10 39.4 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY61919.1 - 2.6e-07 30.6 10.5 5.2e-07 29.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 ORY61920.1 - 9.4e-33 113.4 0.0 2.1e-15 56.2 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY61920.1 - 1.4e-09 37.7 0.0 4.6e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY61920.1 - 3.7e-06 27.1 0.0 8.3e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY61920.1 - 5.5e-06 25.8 0.0 3.8e-05 23.1 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY61920.1 - 5.4e-05 22.5 0.1 0.035 13.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ORY61920.1 - 0.00038 19.3 0.0 0.0011 17.8 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 ORY61920.1 - 0.00056 19.6 0.3 0.8 9.2 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY61920.1 - 0.016 15.2 0.3 0.12 12.4 0.1 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ORY61920.1 - 0.027 13.8 0.1 4.6 6.4 0.4 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORY61920.1 - 0.12 11.6 0.2 0.69 9.2 0.3 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY61920.1 - 0.14 11.4 0.1 1.8 7.7 0.1 2.1 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 ORY61920.1 - 0.18 10.9 2.0 0.2 10.7 0.4 1.8 2 1 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 ORY61920.1 - 0.19 11.0 0.4 0.3 10.4 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF5520 PF17658.1 ORY61921.1 - 0.075 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) Ribosomal_S11 PF00411.19 ORY61923.1 - 4.5e-05 23.8 3.0 0.048 14.1 0.1 3.0 2 1 0 2 2 2 2 Ribosomal protein S11 MafB19-deam PF14437.6 ORY61924.1 - 1.5e-11 44.2 0.0 3.5e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 ORY61924.1 - 1.7e-11 43.9 0.0 2.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region F-box-like PF12937.7 ORY61925.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like ATP_bind_3 PF01171.20 ORY61926.1 - 7.5e-35 120.3 0.0 9.4e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 ORY61926.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.19 ORY61926.1 - 0.21 11.6 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family S1 PF00575.23 ORY61927.1 - 4.8e-14 52.5 0.0 1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 ORY61927.1 - 2e-13 50.5 0.0 3.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 ORY61927.1 - 0.00035 20.8 0.0 0.00051 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 MCM_bind PF09739.9 ORY61928.1 - 1.7e-93 314.1 0.0 3.2e-79 266.9 0.0 2.1 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor WD40 PF00400.32 ORY61929.1 - 6.8e-15 55.2 7.3 0.00086 20.1 0.1 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY61929.1 - 6.8e-06 26.3 0.0 0.06 13.7 0.0 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY61929.1 - 0.11 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Na_H_Exchanger PF00999.21 ORY61930.1 - 4.3e-53 180.5 17.5 5.1e-53 180.2 17.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY61930.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.8 3 0 0 3 3 3 0 YrhC-like protein DUF4267 PF14087.6 ORY61931.1 - 0.00036 20.6 4.3 0.00055 20.0 4.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) Abhydrolase_1 PF00561.20 ORY61933.1 - 2.3e-46 158.6 0.0 1.7e-45 155.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY61933.1 - 0.00056 19.6 0.1 0.001 18.8 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ORY61933.1 - 0.034 13.4 0.1 2.6 7.2 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DASH_Dad2 PF08654.10 ORY61934.1 - 5e-16 58.9 0.0 6.2e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF1776 PF08643.10 ORY61935.1 - 5.4e-19 68.7 0.0 8.1e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) SelK_SelG PF10961.8 ORY61935.1 - 0.058 14.0 0.9 11 6.8 0.0 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG HEAT_2 PF13646.6 ORY61936.1 - 2.8e-06 27.6 1.2 0.032 14.6 0.1 3.6 3 0 0 3 3 3 2 HEAT repeats Pkinase PF00069.25 ORY61936.1 - 0.00014 21.3 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 ORY61936.1 - 0.0002 21.5 0.0 0.00084 19.4 0.0 1.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY61936.1 - 0.00052 20.0 1.0 4 8.0 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat Pkinase_Tyr PF07714.17 ORY61936.1 - 0.0081 15.5 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AAA PF00004.29 ORY61937.1 - 5.5e-41 140.1 0.0 9.2e-41 139.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY61937.1 - 4.5e-08 32.8 0.1 1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORY61937.1 - 6.9e-05 22.9 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY61937.1 - 8.5e-05 22.8 0.0 0.0051 17.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 ORY61937.1 - 0.00034 20.8 0.0 0.00063 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORY61937.1 - 0.0023 17.1 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 ORY61937.1 - 0.0026 18.2 0.1 0.054 13.9 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY61937.1 - 0.0086 15.8 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY61937.1 - 0.0091 16.2 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY61937.1 - 0.011 15.2 0.0 0.028 14.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY61937.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORY61937.1 - 0.03 13.7 0.1 0.2 11.0 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY61937.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 ORY61937.1 - 0.074 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 ORY61937.1 - 0.09 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY61937.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase GST_N_3 PF13417.6 ORY61939.1 - 5e-14 52.5 0.0 9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY61939.1 - 9.4e-09 35.5 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY61939.1 - 0.0088 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CBM_48 PF02922.18 ORY61939.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GST_N_4 PF17172.4 ORY61939.1 - 0.17 12.6 0.0 0.26 12.0 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain HSP70 PF00012.20 ORY61940.1 - 0.00096 17.5 1.4 0.001 17.3 1.4 1.0 1 0 0 1 1 1 1 Hsp70 protein Bacteriocin_IIc PF10439.9 ORY61940.1 - 2 8.6 9.3 2.8 8.1 9.3 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide HSP70 PF00012.20 ORY61941.1 - 2.5e-250 831.8 5.3 3.1e-250 831.5 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY61941.1 - 2.4e-15 56.2 0.2 5.9e-14 51.6 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORY61941.1 - 0.0025 17.6 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORY61941.1 - 0.0099 15.2 0.2 0.027 13.7 0.2 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Aldo_ket_red PF00248.21 ORY61942.1 - 6.6e-36 124.0 0.0 9.6e-36 123.5 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family Fapy_DNA_glyco PF01149.24 ORY61943.1 - 5.7e-27 94.6 0.0 1.3e-26 93.5 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 ORY61943.1 - 3.6e-19 68.6 0.0 1.2e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain Pox_Ag35 PF03286.14 ORY61943.1 - 0.008 16.0 7.0 0.012 15.4 7.0 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein FAM176 PF14851.6 ORY61943.1 - 0.045 13.4 4.3 0.079 12.6 4.3 1.4 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.19 ORY61943.1 - 0.17 12.5 10.4 0.7 10.5 8.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein MCM_bind PF09739.9 ORY61943.1 - 0.25 9.8 0.7 0.33 9.4 0.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Sporozoite_P67 PF05642.11 ORY61943.1 - 0.3 9.1 4.6 0.42 8.6 4.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Vfa1 PF08432.10 ORY61943.1 - 0.35 11.2 5.5 0.65 10.3 5.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4770 PF15994.5 ORY61943.1 - 0.36 11.0 2.0 0.59 10.3 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) CDC45 PF02724.14 ORY61943.1 - 1.1 7.5 5.5 1.5 7.1 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Atrophin-1 PF03154.15 ORY61943.1 - 1.3 7.3 8.1 1.8 6.8 8.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family FancD2 PF14631.6 ORY61943.1 - 3.5 4.9 4.1 4.9 4.4 4.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease TFB6 PF17110.5 ORY61943.1 - 3.6 7.3 5.0 5.8 6.6 5.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CENP-B_dimeris PF09026.10 ORY61943.1 - 8.1 6.9 7.8 16 5.9 7.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MscS_TM PF12794.7 ORY61943.1 - 8.4 5.1 6.9 13 4.6 6.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RPN2_C PF18004.1 ORY61943.1 - 9.4 6.1 12.7 17 5.3 12.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 ORY61943.1 - 9.5 4.2 10.7 13 3.7 10.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_16 PF10294.9 ORY61945.1 - 7.5e-14 51.8 0.0 3.3e-10 40.0 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY61945.1 - 3.1e-07 30.4 0.0 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY61945.1 - 0.034 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 ORY61945.1 - 0.13 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORY61945.1 - 0.19 12.5 0.0 0.39 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 ORY61945.1 - 0.27 10.6 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cpn60_TCP1 PF00118.24 ORY61946.1 - 3.7e-140 467.8 6.7 5.1e-140 467.4 6.7 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NTF2 PF02136.20 ORY61947.1 - 2.2e-33 115.4 0.1 2.5e-33 115.2 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 ORY61947.1 - 0.046 14.1 0.0 0.054 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) F-box-like PF12937.7 ORY61949.1 - 0.0019 18.0 0.1 0.0046 16.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like RRM_1 PF00076.22 ORY61951.1 - 2.9e-25 87.9 0.0 1.2e-12 47.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 ORY61951.1 - 6e-13 47.7 0.0 0.0033 17.0 0.0 4.9 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 ORY61951.1 - 0.0065 16.3 0.0 0.33 10.9 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif E1-E2_ATPase PF00122.20 ORY62701.1 - 2.8e-27 95.4 0.6 2.8e-27 95.4 0.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY62701.1 - 1.1e-19 71.6 0.1 2.6e-12 47.5 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 ORY62701.1 - 4.8e-19 68.7 0.0 2e-18 66.7 0.0 2.1 1 1 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.21 ORY62701.1 - 6.3e-06 26.0 7.6 6.3e-06 26.0 7.6 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY62701.1 - 1.8e-05 24.8 0.0 3.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY62701.1 - 0.00043 19.9 0.0 0.00098 18.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Questin_oxidase PF14027.6 ORY62702.1 - 1.6e-88 297.5 0.0 2.1e-88 297.1 0.0 1.1 1 0 0 1 1 1 1 Questin oxidase-like Mtc PF03820.17 ORY62703.1 - 1.4e-115 385.6 0.0 1.6e-115 385.4 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Annexin PF00191.20 ORY62705.1 - 3.3e-47 158.4 1.8 8.6e-14 51.4 0.2 4.2 4 0 0 4 4 4 4 Annexin SAM_Exu PF18609.1 ORY62705.1 - 0.058 13.5 1.9 11 6.2 0.0 4.1 4 1 1 5 5 5 0 Exuperantia SAM-like domain DUF4292 PF14125.6 ORY62705.1 - 0.072 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) Extensin_2 PF04554.13 ORY62705.1 - 2.5 8.2 82.9 4.9 7.3 34.5 3.8 1 1 3 4 4 4 0 Extensin-like region Zn_clus PF00172.18 ORY62706.1 - 5e-08 32.9 9.6 8.6e-08 32.2 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ELMO_CED12 PF04727.13 ORY62706.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 ELMO/CED-12 family Zn_clus PF00172.18 ORY62707.1 - 3.4e-06 27.1 11.6 6.1e-06 26.3 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PNP_UDP_1 PF01048.20 ORY62708.1 - 5.3e-40 137.1 1.0 9.8e-40 136.3 1.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily MFS_1 PF07690.16 ORY62710.1 - 3.9e-33 114.8 41.1 3.9e-33 114.8 41.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3341 PF11821.8 ORY62710.1 - 0.32 10.6 4.6 0.77 9.4 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Metallophos PF00149.28 ORY62711.1 - 1.9e-25 90.6 0.2 7.1e-25 88.7 0.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 ORY62711.1 - 2e-24 85.7 0.0 3.3e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 ORY62711.1 - 0.031 14.1 0.0 2.3 8.2 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY62711.1 - 0.036 14.5 0.0 2.6 8.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_26 PF02156.15 ORY62712.1 - 0.015 14.7 5.2 1.6 8.1 2.9 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 CHCH PF06747.13 ORY62713.1 - 1.4e-06 28.2 3.8 2.4e-06 27.5 3.8 1.4 1 0 0 1 1 1 1 CHCH domain G-alpha PF00503.20 ORY62715.1 - 3.2e-104 348.9 0.0 3.9e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY62715.1 - 2.6e-16 59.6 0.4 2.1e-11 43.6 0.1 2.9 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY62715.1 - 0.00012 21.6 2.7 0.0051 16.2 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY62715.1 - 0.016 15.5 0.3 2.1 8.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY62715.1 - 0.064 13.3 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase TniB PF05621.11 ORY62715.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DNA_ligase_IV PF11411.8 ORY62715.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 DNA ligase IV AAA_29 PF13555.6 ORY62715.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 ORY62716.1 - 2.9e-98 329.3 0.1 3.4e-98 329.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY62716.1 - 1.8e-13 50.3 1.3 1.1e-09 38.0 0.3 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY62716.1 - 2.3e-05 23.9 0.2 0.003 16.9 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY62716.1 - 0.00036 20.7 0.2 0.89 9.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY62716.1 - 0.019 15.0 0.0 7.8 6.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Rota_NS53 PF00981.17 ORY62716.1 - 0.033 13.1 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) AAA_29 PF13555.6 ORY62716.1 - 0.052 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 ORY62717.1 - 2.1e-69 232.4 0.0 2.6e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ORY62717.1 - 2.1e-07 31.2 0.0 3.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY62717.1 - 0.00019 21.1 0.1 0.00058 19.5 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY62717.1 - 0.0018 18.8 0.0 0.0033 18.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY62717.1 - 0.0046 16.0 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PhoH PF02562.16 ORY62717.1 - 0.0074 15.8 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein IstB_IS21 PF01695.17 ORY62717.1 - 0.0088 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein CbiA PF01656.23 ORY62717.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 ORY62717.1 - 0.012 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 ORY62717.1 - 0.014 15.9 0.0 0.019 15.4 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 ORY62717.1 - 0.014 15.7 0.1 0.024 15.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ORY62717.1 - 0.015 15.8 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY62717.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 ORY62717.1 - 0.022 14.2 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 ORY62717.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 ORY62717.1 - 0.052 13.4 0.2 0.079 12.9 0.2 1.4 1 1 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 ORY62717.1 - 0.06 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ArsA_ATPase PF02374.15 ORY62717.1 - 0.079 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase DUF815 PF05673.13 ORY62717.1 - 0.094 11.9 0.1 0.37 9.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF815) T2SSE PF00437.20 ORY62717.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sec7 PF01369.20 ORY62718.1 - 3.9e-36 124.5 0.0 5.2e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain IQ_SEC7_PH PF16453.5 ORY62718.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 PH domain Hist_deacetyl PF00850.19 ORY62719.1 - 1.4e-87 294.0 0.0 2.2e-87 293.4 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 ORY62719.1 - 3e-40 138.0 0.0 4.9e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain SAP130_C PF16014.5 ORY62719.1 - 2.8 6.9 10.3 4.7 6.2 10.3 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DUF262 PF03235.14 ORY62720.1 - 1.7e-11 44.7 0.0 8e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function DUF262 DUF262 PF03235.14 ORY62721.1 - 1.4e-15 58.0 0.6 2.4e-15 57.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 SF1-HH PF16275.5 ORY62721.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain GEN1_C PF18380.1 ORY62721.1 - 2.4 9.1 7.9 0.75 10.7 2.3 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Mg_trans_NIPA PF05653.14 ORY62722.1 - 4.6e-14 52.2 12.7 1.7e-09 37.3 5.7 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORY62722.1 - 3e-05 24.2 5.7 3e-05 24.2 5.7 3.3 3 1 0 3 3 3 2 EamA-like transporter family DmsC PF04976.12 ORY62722.1 - 1.9 7.9 10.4 0.069 12.6 3.1 2.2 3 0 0 3 3 3 0 DMSO reductase anchor subunit (DmsC) YrhC PF14143.6 ORY62722.1 - 4.5 7.4 5.2 3.3 7.9 0.1 2.9 3 0 0 3 3 3 0 YrhC-like protein DUF4064 PF13273.6 ORY62722.1 - 7.2 7.0 11.5 5 7.5 0.3 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF4064) GMC_oxred_N PF00732.19 ORY62724.1 - 3.5e-68 230.2 0.0 4.4e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY62724.1 - 1.3e-32 113.2 0.0 2.2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY62724.1 - 8.1e-05 21.8 0.1 0.00012 21.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ORY62724.1 - 0.0012 19.0 0.1 0.0035 17.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY62724.1 - 0.0037 16.9 0.0 0.02 14.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY62724.1 - 0.0068 15.5 0.0 0.052 12.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY62724.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY62724.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 ORY62724.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HK PF02110.15 ORY62726.1 - 2.1e-71 240.2 0.5 2.9e-71 239.8 0.5 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 ORY62726.1 - 2e-49 167.4 0.0 3.9e-49 166.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 ORY62726.1 - 0.032 13.6 0.1 0.084 12.2 0.1 1.6 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase Nucleotid_trans PF03407.16 ORY62727.1 - 8.7e-08 32.4 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase EGF_MSP1_1 PF12946.7 ORY62727.1 - 0.69 10.0 5.6 1.3 9.1 5.6 1.4 1 0 0 1 1 1 0 MSP1 EGF domain 1 DUF5129 PF17173.4 ORY62728.1 - 0.22 10.6 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) Vps39_1 PF10366.9 ORY62729.1 - 1.4e-30 105.7 1.6 2.8e-30 104.8 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 ORY62729.1 - 3.3e-26 91.9 0.0 7.6e-26 90.7 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 ORY62729.1 - 1.3e-12 47.8 0.3 7.3e-08 32.4 0.0 2.5 2 0 0 2 2 2 2 Region in Clathrin and VPS CNH PF00780.22 ORY62729.1 - 7.4e-08 32.3 0.0 2.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 CNH domain Zn_Tnp_IS1595 PF12760.7 ORY62729.1 - 0.18 11.8 0.5 0.38 10.8 0.5 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TPR_8 PF13181.6 ORY62729.1 - 0.48 10.8 2.1 47 4.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4834 PF16118.5 ORY62730.1 - 0.28 12.2 0.4 37 5.4 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) GHMP_kinases_N PF00288.26 ORY62731.1 - 1.5e-13 50.8 0.0 5.6e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY62731.1 - 5.2e-08 33.1 0.0 1.5e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal F-box-like PF12937.7 ORY62732.1 - 0.0008 19.3 0.1 0.0024 17.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY62732.1 - 0.016 15.0 2.6 0.05 13.5 2.5 2.0 1 1 0 1 1 1 0 F-box domain DUF2157 PF09925.9 ORY62733.1 - 0.13 12.1 3.4 0.13 12.1 0.9 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) HHH PF00633.23 ORY62734.1 - 0.0021 17.9 0.1 0.0048 16.7 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF5641 PF18701.1 ORY62734.1 - 0.25 11.6 2.9 0.2 11.9 0.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5641) IGPD PF00475.18 ORY62735.1 - 7.2e-61 204.7 0.4 1.9e-60 203.3 0.3 1.6 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase LRR_4 PF12799.7 ORY62738.1 - 0.078 13.4 0.8 1.9 9.0 0.0 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) ThiF PF00899.21 ORY62739.1 - 7.3e-40 136.9 0.0 1.2e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORY62739.1 - 3.4e-05 24.1 0.5 0.00042 20.6 0.5 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 ORY62739.1 - 0.0086 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 ORY62739.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 ORY62739.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORY62739.1 - 0.028 14.9 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 ORY62739.1 - 0.041 13.9 0.0 0.083 13.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ORY62739.1 - 0.044 13.4 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORY62739.1 - 0.054 13.4 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORY62739.1 - 0.11 11.7 0.2 0.2 10.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Peptidase_M48_N PF16491.5 ORY62835.1 - 2.5e-39 135.1 4.1 2.5e-39 135.1 4.1 2.6 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORY62835.1 - 9.9e-34 116.8 0.0 1.7e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 ORY62835.1 - 0.047 12.9 2.5 0.16 11.2 2.5 1.9 1 1 0 1 1 1 0 BlaR1 peptidase M56 Endomucin PF07010.12 ORY62836.1 - 0.0038 17.2 22.3 0.0038 17.2 22.3 2.0 2 0 0 2 2 2 1 Endomucin Macoilin PF09726.9 ORY62836.1 - 0.016 13.8 0.7 0.027 13.0 0.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF4834 PF16118.5 ORY62836.1 - 0.06 14.3 0.1 9.5 7.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) TMEM154 PF15102.6 ORY62836.1 - 0.06 13.2 0.2 0.06 13.2 0.2 2.6 1 1 1 2 2 2 0 TMEM154 protein family Abhydrolase_2 PF02230.16 ORY62837.1 - 7.3e-30 104.4 0.0 7.5e-29 101.1 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY62837.1 - 0.00088 18.6 0.1 0.32 10.2 0.2 2.7 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 ORY62837.1 - 0.0062 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY62837.1 - 0.019 14.4 0.0 4.1 6.8 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.13 ORY62837.1 - 0.023 14.3 0.0 0.054 13.2 0.0 1.5 2 0 0 2 2 2 0 Serine hydrolase (FSH1) EXS PF03124.14 ORY62838.1 - 1.1e-107 360.2 4.3 1.3e-107 359.9 4.3 1.0 1 0 0 1 1 1 1 EXS family PHD PF00628.29 ORY62839.1 - 3e-07 30.2 5.4 6e-07 29.3 5.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_Oberon PF07227.11 ORY62839.1 - 0.017 15.0 0.8 0.033 14.1 0.8 1.4 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein Prok-RING_1 PF14446.6 ORY62839.1 - 0.086 12.8 2.6 0.17 11.8 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 ORY62839.1 - 0.11 12.7 2.8 0.38 10.9 2.8 2.1 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 ORY62839.1 - 0.24 11.7 1.0 0.56 10.5 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Microvir_H PF04687.12 ORY62839.1 - 0.38 10.1 4.9 0.62 9.4 4.9 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) CRAL_TRIO PF00650.20 ORY62840.1 - 4.1e-15 55.8 0.0 5.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY62840.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Utp14 PF04615.13 ORY62841.1 - 0.062 11.9 1.5 0.081 11.5 1.5 1.1 1 0 0 1 1 1 0 Utp14 protein SPX PF03105.19 ORY62841.1 - 0.54 10.1 8.5 0.67 9.8 8.5 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 ORY62841.1 - 0.62 8.9 6.4 0.8 8.5 6.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.13 ORY62841.1 - 0.67 9.5 3.1 0.91 9.1 3.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Plasmodium_Vir PF05795.11 ORY62841.1 - 1.8 7.9 4.0 2.7 7.3 4.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SpoIIIAH PF12685.7 ORY62841.1 - 3.3 7.5 13.3 10 5.9 13.5 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein Sec10 PF07393.11 ORY62841.1 - 8.9 4.6 9.3 12 4.2 9.3 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Vps55 PF04133.14 ORY62843.1 - 8.4e-40 135.4 11.6 9.9e-40 135.1 11.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4231 PF14015.6 ORY62843.1 - 6.9 7.2 7.9 23 5.5 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) adh_short_C2 PF13561.6 ORY62844.1 - 3.3e-39 134.8 0.0 6.5e-39 133.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY62844.1 - 8e-37 126.6 0.0 1.5e-36 125.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY62844.1 - 2.8e-11 43.7 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY62844.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY62844.1 - 0.044 13.2 0.1 0.086 12.3 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY62844.1 - 0.087 11.9 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 ORY62844.1 - 0.17 11.8 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 ORY62844.1 - 0.2 11.7 0.2 0.36 10.9 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.16 ORY62845.1 - 2.1e-16 59.8 48.9 1.3e-15 57.2 24.4 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 ORY62845.1 - 0.51 10.6 7.1 24 5.3 0.0 4.2 3 0 0 3 3 3 0 Transglycosylase associated protein zf-C2H2_assoc PF16606.5 ORY62847.1 - 0.086 13.1 9.2 1.3 9.3 4.5 2.8 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF4232 PF14016.6 ORY62847.1 - 1.9 8.6 5.9 7.4 6.7 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) PLAC8 PF04749.17 ORY62849.1 - 1.6e-21 77.1 17.0 1.9e-21 76.9 17.0 1.0 1 0 0 1 1 1 1 PLAC8 family HMG_box PF00505.19 ORY62850.1 - 2.8e-12 46.9 1.7 4.9e-12 46.1 1.7 1.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY62850.1 - 0.0031 18.1 0.3 0.0075 16.8 0.3 1.6 1 1 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 ORY62850.1 - 0.0089 15.3 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Sacchrp_dh_C PF16653.5 ORY62851.1 - 1.7e-86 290.6 0.0 2.6e-86 290.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Spermine_synth PF01564.17 ORY62851.1 - 1.6e-65 220.0 0.0 5.6e-65 218.3 0.0 1.9 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Sacchrp_dh_NADP PF03435.18 ORY62851.1 - 3.4e-25 88.8 1.4 7.3e-25 87.7 0.6 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Spermine_synt_N PF17284.2 ORY62851.1 - 9.8e-20 70.2 0.7 2.7e-19 68.8 0.1 2.1 2 0 0 2 2 2 1 Spermidine synthase tetramerisation domain Shikimate_DH PF01488.20 ORY62851.1 - 1.2e-07 31.9 0.6 7.9e-07 29.2 0.3 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.6 ORY62851.1 - 9.2e-07 29.5 0.1 0.0006 20.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain NAD_binding_10 PF13460.6 ORY62851.1 - 4.8e-05 23.3 0.9 9.9e-05 22.3 0.6 1.7 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 ORY62851.1 - 0.0047 17.5 0.2 0.011 16.3 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 ORY62851.1 - 0.0048 16.2 1.9 0.0052 16.1 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3Beta_HSD PF01073.19 ORY62851.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORY62851.1 - 0.089 12.3 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family GFO_IDH_MocA PF01408.22 ORY62851.1 - 0.13 13.1 0.2 0.33 11.8 0.2 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_12 PF08242.12 ORY62851.1 - 0.17 12.7 0.1 0.92 10.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_3 PF13302.7 ORY62853.1 - 5.9e-08 33.5 0.0 9.2e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY62853.1 - 0.0054 17.0 0.0 0.0079 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4357 PF14267.6 ORY62853.1 - 0.29 11.1 4.5 0.56 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Rad60-SLD PF11976.8 ORY62855.1 - 3.5e-14 52.4 0.0 4e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY62855.1 - 0.0006 19.5 0.0 0.00091 18.9 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin family DUF905 PF06006.12 ORY62855.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Lbh PF15317.6 ORY62856.1 - 0.026 15.3 0.2 0.041 14.7 0.2 1.3 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein Pkinase PF00069.25 ORY62857.1 - 6.9e-57 192.8 0.0 3.3e-52 177.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY62857.1 - 5.3e-32 111.1 0.0 6e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 ORY62857.1 - 8.2e-15 54.3 0.1 1.5e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 ORY62857.1 - 1.7e-05 24.3 0.0 8.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY62857.1 - 5.8e-05 22.5 0.0 9.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY62857.1 - 0.0001 21.4 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY62857.1 - 0.0012 18.8 0.0 0.0037 17.2 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.11 ORY62857.1 - 0.059 13.0 0.1 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Mpp10 PF04006.12 ORY62857.1 - 2.7 6.3 8.3 4.2 5.7 8.3 1.2 1 0 0 1 1 1 0 Mpp10 protein TPR_1 PF00515.28 ORY62858.1 - 1.1e-41 138.9 7.1 1.4e-07 31.0 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY62858.1 - 5.4e-40 132.3 2.1 3.6e-05 23.6 0.1 9.8 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORY62858.1 - 3.6e-31 104.7 2.7 2e-06 27.6 0.0 8.4 7 1 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY62858.1 - 1.6e-27 94.9 2.8 8.4e-08 31.8 0.0 7.0 5 2 2 7 7 7 5 TPR repeat TPR_17 PF13431.6 ORY62858.1 - 1.4e-25 87.8 0.1 3.8e-05 23.8 0.0 9.2 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY62858.1 - 2.1e-23 82.4 5.5 9.3e-05 22.6 0.0 7.4 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY62858.1 - 2.7e-20 72.6 2.5 6.1e-05 23.4 0.0 4.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY62858.1 - 3.4e-19 67.9 3.1 0.0025 18.5 0.0 9.2 3 3 6 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY62858.1 - 8.2e-18 64.8 4.4 4.9e-05 23.9 0.0 6.2 6 1 1 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY62858.1 - 1.2e-14 54.3 4.9 7.3e-06 26.1 0.1 5.4 4 1 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY62858.1 - 4.7e-12 45.0 6.3 0.28 11.3 0.0 7.5 7 1 0 7 7 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY62858.1 - 1.2e-10 40.8 10.6 0.028 14.3 0.0 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY62858.1 - 3e-09 36.5 3.5 0.001 18.4 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY62858.1 - 2.1e-08 34.2 0.2 0.0085 16.2 0.0 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY62858.1 - 1.3e-07 31.8 2.7 0.052 14.2 0.0 6.6 7 0 0 7 7 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY62858.1 - 1.4e-06 27.7 1.8 0.03 13.8 0.1 4.5 4 0 0 4 4 4 2 SHNi-TPR TPR_MalT PF17874.1 ORY62858.1 - 2.9e-05 23.6 0.7 0.0015 18.0 2.0 2.8 3 1 0 3 3 3 1 MalT-like TPR region TPR_20 PF14561.6 ORY62858.1 - 0.00047 20.4 7.6 5.6 7.4 0.0 5.4 3 1 2 5 5 5 1 Tetratricopeptide repeat TAF1_subA PF14929.6 ORY62858.1 - 0.0028 17.2 5.2 0.024 14.1 3.6 2.6 2 1 0 2 2 2 1 TAF RNA Polymerase I subunit A TPR_18 PF13512.6 ORY62858.1 - 0.0028 17.8 0.7 0.02 15.0 0.2 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 ORY62858.1 - 0.0039 16.9 11.8 1.8 8.2 0.6 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat-like domain YfiO PF13525.6 ORY62858.1 - 0.0041 16.9 4.2 0.0057 16.4 1.0 2.8 2 1 1 3 3 3 1 Outer membrane lipoprotein BCIP PF13862.6 ORY62858.1 - 0.012 15.4 2.6 0.19 11.5 0.0 2.8 3 0 0 3 3 3 0 p21-C-terminal region-binding protein PknG_TPR PF16918.5 ORY62858.1 - 0.025 13.3 0.2 0.25 10.0 0.1 2.2 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat SR-25 PF10500.9 ORY62858.1 - 0.057 13.0 9.0 0.1 12.2 9.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.7 ORY62858.1 - 0.12 12.2 5.9 0.043 13.6 3.1 1.7 2 0 0 2 2 1 0 SpoIIIAH-like protein Dsh_C PF12316.8 ORY62858.1 - 0.31 11.4 8.0 0.6 10.5 8.0 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal ANAPC5 PF12862.7 ORY62858.1 - 0.53 10.4 7.5 8.6 6.5 0.4 4.4 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 SKG6 PF08693.10 ORY62860.1 - 0.0069 15.8 0.1 0.015 14.7 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 ORY62860.1 - 0.034 14.0 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Acetyltransf_10 PF13673.7 ORY62861.1 - 3.5e-09 36.7 0.0 5.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY62861.1 - 2.1e-08 34.4 0.0 3.9e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY62861.1 - 7.3e-07 29.5 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY62861.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 ORY62861.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Proteasome PF00227.26 ORY62863.1 - 2.1e-48 164.4 0.2 1.5e-47 161.6 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY62863.1 - 4.4e-12 45.4 0.2 1.1e-11 44.2 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_60s PF00428.19 ORY62863.1 - 0.23 12.1 11.3 0.6 10.7 11.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein HMG_box PF00505.19 ORY62864.1 - 2.9e-12 46.8 5.2 1.4e-11 44.7 5.2 1.8 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY62864.1 - 4.7e-07 30.3 0.0 5.3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain SPC12 PF06645.13 ORY62865.1 - 4.2e-23 81.2 0.1 5e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) OEP PF02321.18 ORY62866.1 - 0.015 15.1 1.1 0.015 15.1 1.1 1.5 2 0 0 2 2 2 0 Outer membrane efflux protein adh_short PF00106.25 ORY62867.1 - 2.3e-30 105.5 0.0 4.7e-30 104.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY62867.1 - 2e-29 102.8 0.0 3.9e-29 101.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 ORY62867.1 - 0.015 14.6 0.1 0.035 13.4 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain V_ATPase_prox PF18274.1 ORY62867.1 - 0.08 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe KR PF08659.10 ORY62867.1 - 0.15 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 KR domain Met_10 PF02475.16 ORY62868.1 - 3e-62 209.9 0.0 3.9e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ORY62868.1 - 0.005 16.1 0.0 0.0068 15.6 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 ORY62868.1 - 0.028 14.0 0.0 0.07 12.7 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 ORY62868.1 - 0.068 12.8 0.1 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PrmA PF06325.13 ORY62868.1 - 0.07 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY62868.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain FMO-like PF00743.19 ORY62871.1 - 4.5e-18 65.0 0.0 9e-07 27.7 0.0 3.9 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY62871.1 - 7.5e-06 25.4 0.0 0.0085 15.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY62871.1 - 0.00099 18.3 0.0 0.086 12.0 0.1 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY62871.1 - 0.0043 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY62871.1 - 0.0066 16.4 0.2 0.046 13.7 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding CDC27 PF09507.10 ORY62871.1 - 0.17 11.2 7.7 0.24 10.7 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SUI1 PF01253.22 ORY62872.1 - 9.3e-29 99.8 1.1 1.5e-28 99.1 1.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ras PF00071.22 ORY62874.1 - 5.8e-47 159.3 0.0 7.1e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY62874.1 - 1.2e-28 99.8 0.0 1.5e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY62874.1 - 1.8e-13 50.3 0.0 2.4e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY62874.1 - 1.1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY62874.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 ORY62874.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY62874.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY62874.1 - 0.017 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY62874.1 - 0.082 13.3 0.1 0.13 12.6 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 ORY62874.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 ORY62874.1 - 0.2 11.6 0.0 0.96 9.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase TPR_14 PF13428.6 ORY62875.1 - 1.7e-10 40.8 19.7 0.0059 17.3 4.1 8.6 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY62875.1 - 1e-06 28.4 9.1 2.9 8.2 0.5 8.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY62875.1 - 0.0013 19.2 4.8 0.36 11.4 0.6 4.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY62875.1 - 0.0022 17.7 0.0 32 4.5 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY62875.1 - 0.015 15.9 10.5 0.066 13.9 1.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MLTD_N PF06474.12 ORY62875.1 - 0.18 12.0 3.1 0.2 11.9 0.1 2.7 3 0 0 3 3 3 0 MltD lipid attachment motif Symplekin_C PF12295.8 ORY62875.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal MPLKIP PF15502.6 ORY62876.1 - 0.049 13.9 0.2 0.049 13.9 0.2 2.3 2 2 0 2 2 2 0 M-phase-specific PLK1-interacting protein p450 PF00067.22 ORY62877.1 - 1.3e-70 238.5 0.0 1.7e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Solute_trans_a PF03619.16 ORY62878.1 - 1.7e-75 254.0 15.5 2.2e-75 253.6 15.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha zf-C2H2 PF00096.26 ORY62879.1 - 3.4e-05 24.1 8.3 0.009 16.4 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORY62879.1 - 0.0022 18.2 5.6 0.11 12.6 0.5 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ORY62879.1 - 0.0032 18.2 6.7 0.98 10.4 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Glycos_transf_1 PF00534.20 ORY63655.1 - 6.2e-29 100.7 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY63655.1 - 2.9e-25 89.2 0.0 5.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY63655.1 - 4e-21 75.8 0.0 1.8e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORY63655.1 - 4.4e-11 43.5 0.0 1.3e-09 38.7 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain DUF5476 PF17570.2 ORY63655.1 - 0.0045 17.4 0.2 0.011 16.1 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5476) Glyco_trans_1_2 PF13524.6 ORY63655.1 - 0.012 16.0 0.1 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 DDA1 PF10172.9 ORY63655.1 - 0.04 14.2 1.6 0.08 13.2 1.6 1.5 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase OPT PF03169.15 ORY63656.1 - 1.2e-142 476.7 38.7 1.4e-142 476.5 38.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein VIT1 PF01988.19 ORY63656.1 - 7.9 6.3 14.8 6.2 6.6 0.1 4.3 4 1 0 4 4 4 0 VIT family PH_12 PF16457.5 ORY63657.1 - 2.1e-27 96.3 0.0 1.5e-26 93.6 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 ORY63657.1 - 6.5e-25 88.3 0.0 9.9e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 ORY63657.1 - 1.1e-13 51.4 0.0 7.5e-13 48.7 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3361) DUF4479 PF14794.6 ORY63657.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) DUF1712 PF08217.11 ORY63658.1 - 9.6e-15 54.1 0.0 1.4e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Astro_capsid_p PF12226.8 ORY63658.1 - 5.5 6.0 7.7 9.6 5.2 7.7 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Hus1 PF04005.12 ORY63660.1 - 1.8e-69 234.1 0.0 2.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein p450 PF00067.22 ORY63662.1 - 2.8e-74 250.5 0.0 3.6e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cation_efflux PF01545.21 ORY63662.1 - 8.9e-47 159.4 4.9 1.9e-46 158.3 4.9 1.6 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY63662.1 - 0.012 15.7 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter CTV_P6 PF06706.11 ORY63662.1 - 0.12 12.1 0.0 0.48 10.2 0.0 1.9 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein MycE_N PF17843.1 ORY63662.1 - 0.14 12.6 0.3 0.9 10.0 0.0 2.3 2 0 0 2 2 2 0 MycE methyltransferase N-terminal Sec6 PF06046.13 ORY63663.1 - 3.1e-151 504.6 5.1 4.2e-151 504.2 5.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 DUF2120 PF09893.9 ORY63663.1 - 0.02 15.0 1.8 0.12 12.5 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Vps53_N PF04100.12 ORY63663.1 - 0.057 12.4 0.5 0.34 9.8 0.1 2.4 2 0 0 2 2 2 0 Vps53-like, N-terminal SHNi-TPR PF10516.9 ORY63663.1 - 0.072 12.6 0.0 14 5.3 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR Spc7 PF08317.11 ORY63663.1 - 0.27 10.1 2.8 10 4.9 0.1 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein CN_hydrolase PF00795.22 ORY63664.1 - 2.3e-42 145.2 0.0 3.1e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 ORY63664.1 - 1.6e-22 79.8 0.0 6.8e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 NAD synthase MENTAL PF10457.9 ORY63665.1 - 0.048 13.5 3.8 0.099 12.4 3.8 1.5 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF2583 PF10762.9 ORY63665.1 - 3.3 8.2 5.3 3.2 8.3 1.2 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2583) Capsid_NCLDV PF04451.12 ORY63666.1 - 0.16 11.7 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Large eukaryotic DNA virus major capsid protein Oleosin PF01277.17 ORY63666.1 - 3.2 7.5 12.5 0.25 11.1 6.4 2.3 1 1 1 2 2 2 0 Oleosin Na_Ca_ex PF01699.24 ORY63667.1 - 2.6e-37 128.1 37.7 9.8e-20 71.0 16.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3951 PF13131.6 ORY63667.1 - 0.43 10.8 0.0 0.43 10.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) zf-MYND PF01753.18 ORY63669.1 - 1.3e-10 41.1 13.0 3.6e-10 39.8 13.0 1.7 1 0 0 1 1 1 1 MYND finger MTHFR PF02219.17 ORY63670.1 - 1.9e-112 375.2 0.0 2.6e-112 374.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ssDBP_DBD PF18361.1 ORY63671.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain ANTAR PF03861.14 ORY63671.1 - 0.84 9.5 4.0 10 6.0 0.0 2.9 3 0 0 3 3 3 0 ANTAR domain Pkinase PF00069.25 ORY63672.1 - 7.1e-55 186.2 0.0 4.6e-54 183.5 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY63672.1 - 2.4e-27 95.9 0.0 1.4e-26 93.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY63672.1 - 0.00013 21.0 0.2 0.00017 20.6 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY63672.1 - 0.0057 16.0 0.0 0.0081 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PQ-loop PF04193.14 ORY63673.1 - 8.9e-10 38.2 1.1 0.00044 20.0 0.0 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF2428 PF10350.9 ORY63675.1 - 7.5e-65 218.9 1.1 3.8e-64 216.6 0.0 2.3 2 1 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 ORY63675.1 - 0.0022 18.1 10.7 4.3 7.9 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 ORY63675.1 - 0.0065 16.8 14.7 0.0088 16.4 0.8 4.8 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 ORY63675.1 - 0.74 10.4 11.7 3.1 8.4 1.2 4.4 3 1 1 4 4 4 0 HEAT-like repeat MFS_1 PF07690.16 ORY63676.1 - 5.5e-44 150.5 50.5 5.5e-44 150.5 50.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY63676.1 - 1.7e-11 43.3 26.7 2.5e-11 42.8 26.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) O-FucT PF10250.9 ORY63677.1 - 3.8e-09 36.7 0.0 1.1e-08 35.2 0.0 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.9 ORY63678.1 - 7.7e-10 39.0 0.0 3.8e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Sec7 PF01369.20 ORY63679.1 - 2.2e-31 108.9 0.1 3.3e-31 108.4 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORY63679.1 - 1.7e-13 51.0 0.0 3.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY63679.1 - 5.9e-09 36.4 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 ORY63679.1 - 0.05 13.9 0.0 1.3 9.3 0.0 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain p450 PF00067.22 ORY63680.1 - 2.7e-63 214.3 0.0 3.2e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4240 PF14024.6 ORY63680.1 - 0.036 14.3 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) p450 PF00067.22 ORY63681.1 - 5.7e-64 216.6 0.0 7.4e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nup84_Nup100 PF04121.13 ORY63682.1 - 1.2e-164 549.4 0.0 1.3e-164 549.2 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 FAP PF07174.11 ORY63683.1 - 2.7 7.4 13.3 4.8 6.5 13.3 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) C2 PF00168.30 ORY63684.1 - 2.2e-11 44.0 0.0 1.3e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 C2 domain Glyco_H_20C_C PF18088.1 ORY63685.1 - 1.5e-15 57.5 0.3 1.8e-15 57.3 0.3 1.0 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain Hrs_helical PF12210.8 ORY63685.1 - 0.071 13.7 0.1 0.074 13.6 0.1 1.1 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Glyco_H_20C_C PF18088.1 ORY63686.1 - 8.6e-22 77.9 0.0 2e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Glycoside Hydrolase 20C C-terminal domain Glyco_hydro_20 PF00728.22 ORY63686.1 - 3.6e-12 46.4 0.0 9.3e-11 41.7 0.0 2.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain zf-C2H2_jaz PF12171.8 ORY63687.1 - 8.2e-07 29.2 0.1 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY63687.1 - 0.0039 17.5 0.1 0.0064 16.8 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) TrbC PF04956.13 ORY63688.1 - 0.042 14.1 0.1 0.053 13.7 0.1 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family Dcc1 PF09724.9 ORY63689.1 - 7.3e-56 189.9 0.0 5.7e-34 117.9 0.1 2.1 2 0 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 Transket_pyr PF02779.24 ORY63690.1 - 2.8e-53 180.2 0.0 4.2e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ORY63690.1 - 4.6e-38 130.9 0.0 7.9e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 ORY63690.1 - 7.7e-37 126.3 0.0 1.2e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal PFOR_II PF17147.4 ORY63690.1 - 0.083 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF2263 PF10021.9 ORY63692.1 - 2.1e-23 83.3 0.0 3.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) TPR_15 PF13429.6 ORY63692.1 - 0.24 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat FXMRP1_C_core PF12235.8 ORY63692.1 - 0.26 11.9 5.4 0.098 13.3 2.5 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal FoP_duplication PF13865.6 ORY63692.1 - 1.1 9.9 6.6 2.8 8.6 6.6 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Tir_receptor_N PF07490.11 ORY63694.1 - 0.019 14.8 1.6 0.019 14.8 1.6 2.5 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) N-terminus TMEM154 PF15102.6 ORY63694.1 - 0.058 13.3 0.4 0.058 13.3 0.4 2.6 2 2 0 2 2 2 0 TMEM154 protein family FtsX PF02687.21 ORY63694.1 - 0.15 12.6 0.8 0.3 11.6 0.8 1.5 1 0 0 1 1 1 0 FtsX-like permease family Pox_A14 PF05767.12 ORY63694.1 - 0.17 12.0 0.1 0.35 11.0 0.1 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MFS_1 PF07690.16 ORY63695.1 - 4e-18 65.5 43.0 4e-18 65.5 43.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY63696.1 - 2e-21 76.3 67.5 8.3e-20 71.0 38.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cwf_Cwc_15 PF04889.12 ORY63697.1 - 0.014 15.1 6.5 0.021 14.5 6.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RCR PF12273.8 ORY63697.1 - 0.054 14.2 0.4 0.28 11.8 0.0 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Orf78 PF06024.12 ORY63697.1 - 0.084 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) OSTbeta PF15048.6 ORY63697.1 - 0.11 12.7 0.1 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein EphA2_TM PF14575.6 ORY63697.1 - 0.15 13.0 0.0 0.58 11.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DDRGK PF09756.9 ORY63697.1 - 0.39 10.3 10.2 0.61 9.7 10.2 1.2 1 0 0 1 1 1 0 DDRGK domain Beta_propel PF09826.9 ORY63793.1 - 0.067 12.0 0.0 0.071 11.9 0.0 1.0 1 0 0 1 1 1 0 Beta propeller domain PAM2 PF07145.15 ORY63794.1 - 0.034 13.8 0.1 0.078 12.7 0.1 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region 2OG-FeII_Oxy_2 PF13532.6 ORY63795.1 - 4.5e-22 79.2 0.0 7.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.16 ORY63795.1 - 3.5e-07 29.8 0.0 5.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain Herpes_ICP4_N PF03584.15 ORY63795.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region OsmC PF02566.19 ORY63797.1 - 2e-18 66.7 0.0 2.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Lep_receptor_Ig PF06328.11 ORY63797.1 - 0.097 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Ig-like C2-type domain p450 PF00067.22 ORY63798.1 - 1.4e-62 212.0 0.0 5.1e-61 206.8 0.0 2.6 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.7 ORY63799.1 - 0.00017 21.4 0.1 0.00044 20.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY63799.1 - 0.012 15.4 0.2 0.04 13.8 0.2 2.0 1 0 0 1 1 1 0 F-box domain Erg28 PF03694.13 ORY63800.1 - 3.2e-43 146.6 1.8 3.8e-43 146.4 1.8 1.1 1 0 0 1 1 1 1 Erg28 like protein EOS1 PF12326.8 ORY63800.1 - 0.038 13.9 0.1 0.076 12.9 0.1 1.4 1 1 0 1 1 1 0 N-glycosylation protein S1FA PF04689.13 ORY63800.1 - 0.072 13.2 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 DNA binding protein S1FA Oxidored_FMN PF00724.20 ORY63802.1 - 3.2e-100 335.7 0.0 3.6e-100 335.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cyanate_lyase PF02560.14 ORY63802.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain Oxidored_FMN PF00724.20 ORY63803.1 - 7.8e-95 318.0 0.0 8.9e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cyanate_lyase PF02560.14 ORY63803.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Cyanate lyase C-terminal domain L51_S25_CI-B8 PF05047.16 ORY63804.1 - 0.0047 16.8 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DASH_Hsk3 PF08227.11 ORY63804.1 - 0.058 13.8 0.3 0.11 12.9 0.3 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like Oxidored_FMN PF00724.20 ORY63805.1 - 4.3e-98 328.7 0.0 5.5e-98 328.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DEAD PF00270.29 ORY63806.1 - 5.4e-19 68.6 0.0 1.4e-18 67.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY63806.1 - 1.8e-15 57.2 0.0 4.5e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORY63806.1 - 0.00048 20.8 0.5 0.00099 19.8 0.5 1.5 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 ORY63806.1 - 0.024 14.6 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit QueC PF06508.13 ORY63806.1 - 1.1 8.7 2.7 5.2 6.5 0.8 2.3 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC F-box-like PF12937.7 ORY63807.1 - 1.2e-07 31.5 0.2 3e-07 30.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY63807.1 - 3.6e-05 23.5 0.0 3.6e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY63808.1 - 0.0058 16.5 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like Elf1 PF05129.13 ORY63809.1 - 3.9e-14 52.4 0.6 5.9e-14 51.9 0.1 1.6 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like CDC27 PF09507.10 ORY63809.1 - 2.3 7.5 16.2 2.8 7.3 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DTHCT PF08070.11 ORY63809.1 - 9.3 7.0 14.0 53 4.6 14.0 2.0 1 1 0 1 1 1 0 DTHCT (NUC029) region CoA_trans PF01144.23 ORY63810.1 - 1.1e-97 325.7 5.8 7.4e-57 192.2 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 ORY63810.1 - 0.0017 18.3 0.1 0.0032 17.4 0.1 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Creatinase_N_2 PF16189.5 ORY63811.1 - 1.6e-41 142.1 0.0 1.9e-37 128.9 0.0 3.2 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ORY63811.1 - 1.8e-38 132.3 0.0 3e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ORY63811.1 - 4.5e-18 66.2 0.1 2.2e-16 60.7 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 ORY63811.1 - 8.3e-12 45.0 0.0 2.2e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 DUF1749 PF08538.10 ORY63812.1 - 7.1e-64 215.7 0.0 9.3e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 ORY63812.1 - 2.7e-09 38.0 0.1 3.7e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY63812.1 - 2.3e-05 24.2 0.0 4.8e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY63812.1 - 0.00012 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY63812.1 - 0.012 15.3 0.7 0.17 11.6 0.1 2.5 2 1 0 2 2 2 0 PGAP1-like protein DUF900 PF05990.12 ORY63812.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.11 ORY63812.1 - 0.018 15.0 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Ser_hydrolase PF06821.13 ORY63812.1 - 0.03 14.2 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase adh_short_C2 PF13561.6 ORY63813.1 - 3.1e-20 72.7 0.0 3.9e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY63813.1 - 1.1e-19 70.7 0.1 1.2e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 ORY63814.1 - 2.5e-06 26.7 0.0 4.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY63814.1 - 3.2e-05 24.0 9.3 5.6e-05 23.2 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep3 PF16846.5 ORY63814.1 - 0.033 12.7 0.0 0.051 12.0 0.0 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B TauD PF02668.16 ORY63816.1 - 6.9e-27 94.9 0.0 9.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TRAPPC9-Trs120 PF08626.11 ORY63817.1 - 5.7e-286 951.5 0.0 6.4e-286 951.3 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.11 ORY63817.1 - 0.0036 17.5 0.0 0.2 12.0 0.0 2.8 2 0 0 2 2 2 1 CARDB TPR_1 PF00515.28 ORY63817.1 - 0.011 15.5 0.4 0.14 12.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY63817.1 - 0.019 14.7 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 ORY63817.1 - 0.093 12.9 0.1 0.8 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2267 PF10025.9 ORY63817.1 - 0.12 12.6 1.3 0.33 11.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) TPR_12 PF13424.6 ORY63817.1 - 0.16 12.3 0.1 0.52 10.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY63818.1 - 0.00031 20.6 0.0 0.0013 18.6 0.0 2.2 1 0 0 1 1 1 1 F-box-like PIF1 PF05970.14 ORY63819.1 - 2.6e-10 40.0 3.6 1.3e-07 31.2 2.0 2.7 2 1 1 3 3 3 2 PIF1-like helicase FoP_duplication PF13865.6 ORY63819.1 - 0.012 16.1 0.1 0.024 15.2 0.1 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 AAA_30 PF13604.6 ORY63819.1 - 0.06 13.1 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 ORY63820.1 - 4.7e-28 98.5 0.0 2.4e-27 96.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY63820.1 - 5.6e-28 98.2 0.0 2.1e-25 89.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY63820.1 - 7.2e-21 74.1 0.2 1.9e-20 72.7 0.2 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ORY63820.1 - 1.6e-12 47.4 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain GAS2 PF02187.17 ORY63821.1 - 2.5e-09 37.1 0.1 7e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain TBK1_CCD1 PF18394.1 ORY63821.1 - 0.056 13.0 0.3 0.13 11.8 0.3 1.5 1 0 0 1 1 1 0 TANK-binding kinase 1 coiled-coil domain 1 DUF1640 PF07798.11 ORY63821.1 - 0.2 11.7 7.4 2.1 8.4 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) DUF1843 PF08898.10 ORY63821.1 - 0.32 11.5 3.2 65 4.1 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) IBR PF01485.21 ORY63822.1 - 1.1e-13 51.1 35.2 9e-09 35.4 7.7 4.0 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 ORY63822.1 - 0.046 14.1 0.0 0.046 14.1 0.0 2.8 4 0 0 4 4 4 0 RING/Ubox like zinc-binding domain zinc_ribbon_12 PF11331.8 ORY63822.1 - 0.34 10.7 14.9 3.3 7.6 0.2 4.4 4 1 0 4 4 4 0 Probable zinc-ribbon domain G-alpha PF00503.20 ORY63823.1 - 9.6e-88 294.7 0.1 1.2e-87 294.4 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY63823.1 - 1.2e-13 50.9 0.2 1.5e-08 34.3 0.2 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY63823.1 - 1.6e-05 24.4 0.0 0.003 17.0 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY63823.1 - 0.00062 20.0 0.0 0.98 9.7 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 ORY63823.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY63823.1 - 0.13 11.8 0.0 4.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 ORY63823.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PAP2_3 PF14378.6 ORY63824.1 - 6.1e-19 68.4 13.0 6.1e-19 68.4 13.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 ORY63824.1 - 1.4e-08 34.6 5.1 1.4e-08 34.6 5.1 2.2 2 0 0 2 2 2 1 PAP2 superfamily ATP_synt_H PF05493.13 ORY63824.1 - 0.034 14.6 2.2 0.034 14.6 2.2 2.2 2 0 0 2 2 2 0 ATP synthase subunit H PAP2_C PF14360.6 ORY63824.1 - 0.087 13.4 9.0 0.085 13.4 5.8 2.3 2 0 0 2 2 2 0 PAP2 superfamily C-terminal SGL PF08450.12 ORY63825.1 - 2.8e-21 76.3 0.0 2.5e-10 40.4 0.0 3.0 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORY63825.1 - 0.025 14.8 0.0 0.19 11.9 0.0 2.3 1 1 1 2 2 2 0 Arylesterase NHL PF01436.21 ORY63825.1 - 0.061 13.4 0.0 0.45 10.7 0.0 2.5 2 0 0 2 2 2 0 NHL repeat Actin PF00022.19 ORY63826.1 - 7.1e-91 304.8 0.0 7.2e-89 298.2 0.0 2.0 1 1 0 1 1 1 1 Actin WD40 PF00400.32 ORY63827.1 - 5.6e-25 87.1 14.4 4.2e-06 27.4 0.0 7.8 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY63827.1 - 1.1e-13 51.3 0.1 0.0056 16.9 0.0 5.8 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY63827.1 - 1.5e-08 34.7 0.1 3.2e-05 23.9 0.0 3.6 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORY63827.1 - 1.4e-05 24.9 0.0 0.27 11.2 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ORY63827.1 - 1.9e-05 24.1 0.0 0.0037 16.6 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain VID27 PF08553.10 ORY63827.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.4 1 1 0 1 1 1 0 VID27 C-terminal WD40-like domain Arylsulfotran_2 PF14269.6 ORY63828.1 - 2.3e-54 184.8 2.9 3.5e-54 184.2 2.9 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ORY63828.1 - 2.1e-18 66.4 0.2 4.3e-17 62.1 0.2 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) SMI1_KNR4 PF09346.10 ORY63829.1 - 6.9e-16 58.8 0.0 2.4e-15 57.1 0.0 1.8 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Zn_clus PF00172.18 ORY63830.1 - 0.00028 20.9 8.8 0.00051 20.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 ORY63831.1 - 3.2e-51 173.7 48.7 6.8e-33 113.9 18.7 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY63831.1 - 5.8e-24 85.2 0.0 2.9e-15 57.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY63831.1 - 1.8e-23 82.3 1.5 3.4e-18 65.3 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORY63831.1 - 6.3e-05 22.3 17.6 6.3e-05 22.3 17.6 3.1 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 ORY63831.1 - 0.0003 21.2 0.3 0.64 10.4 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORY63831.1 - 0.0004 20.1 0.5 0.93 9.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY63831.1 - 0.014 15.7 0.1 7.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY63831.1 - 0.035 14.0 0.5 9.3 6.1 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 ORY63831.1 - 0.055 13.0 0.5 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY63831.1 - 0.11 13.0 0.4 5.2 7.5 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ORY63831.1 - 0.12 12.5 0.9 5.1 7.2 0.1 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY63831.1 - 0.16 12.1 0.1 20 5.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY63831.1 - 0.18 12.3 0.2 2.4 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY63831.1 - 1.8 8.1 3.0 7.3 6.1 0.8 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Snf7 PF03357.21 ORY63834.1 - 3.3e-24 85.4 5.9 3.8e-24 85.2 5.9 1.0 1 0 0 1 1 1 1 Snf7 MFS_1 PF07690.16 ORY64596.1 - 6.1e-22 78.0 71.8 1.9e-14 53.4 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_A22B PF04258.13 ORY64597.1 - 6e-78 262.2 2.5 7.9e-78 261.9 2.5 1.0 1 0 0 1 1 1 1 Signal peptide peptidase FAM176 PF14851.6 ORY64597.1 - 0.0016 18.1 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 FAM176 family ESSS PF10183.9 ORY64597.1 - 0.089 13.0 0.1 0.81 9.9 0.0 2.5 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4231 PF14015.6 ORY64597.1 - 0.16 12.5 4.3 0.47 11.0 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SPP PF06550.11 ORY64597.1 - 0.65 9.4 19.8 0.11 11.9 12.7 2.6 2 1 0 2 2 2 0 Signal-peptide peptidase, presenilin aspartyl protease PLDc_2 PF13091.6 ORY64598.1 - 2.7e-18 66.1 0.0 4.4e-12 46.0 0.0 2.9 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 ORY64598.1 - 0.00086 19.4 0.1 0.18 12.1 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif HMA PF00403.26 ORY64599.1 - 1.7e-14 54.0 0.9 2e-14 53.8 0.9 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain EB PF01683.18 ORY64600.1 - 0.0093 16.2 18.6 0.32 11.3 7.8 2.9 2 0 0 2 2 2 2 EB module SLR1-BP PF07333.12 ORY64600.1 - 4 8.0 24.7 0.32 11.5 1.8 3.7 4 0 0 4 4 4 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Pinin_SDK_memA PF04696.13 ORY64601.1 - 0.0063 16.6 4.3 0.0063 16.6 4.3 3.5 4 0 0 4 4 4 1 pinin/SDK/memA/ protein conserved region TFB6 PF17110.5 ORY64601.1 - 1.9 8.2 11.4 0.56 9.9 1.3 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FYDLN_acid PF09538.10 ORY64601.1 - 4.7 8.0 23.6 1.6 9.4 6.5 3.5 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) NTP_transferase PF00483.23 ORY64602.1 - 1.2e-50 172.4 0.0 1.8e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY64602.1 - 2.3e-09 37.8 0.0 3.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 ORY64602.1 - 3.4e-09 36.1 4.6 5.4e-06 25.9 1.8 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 ORY64602.1 - 0.042 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 ORY64602.1 - 0.052 13.5 0.1 0.08 12.8 0.1 1.2 1 0 0 1 1 1 0 Cytidylyltransferase DUF4954 PF16314.5 ORY64602.1 - 0.099 10.8 0.0 0.14 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) PQ-loop PF04193.14 ORY64603.1 - 7.3e-37 125.0 10.3 2.9e-18 65.4 2.1 2.5 2 0 0 2 2 2 2 PQ loop repeat RhoGEF PF00621.20 ORY64604.1 - 1.7e-22 80.5 0.0 3.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain AMPK1_CBM PF16561.5 ORY64605.1 - 6.6e-20 71.1 0.0 9e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 ORY64605.1 - 0.0026 18.1 0.0 0.0042 17.4 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Sec16_C PF12931.7 ORY64606.1 - 4e-62 210.6 0.0 4.4e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Aminotran_4 PF01063.19 ORY64608.1 - 3.1e-25 89.4 0.0 3.8e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF3818 PF12825.7 ORY64609.1 - 8.1e-70 235.5 0.0 4.2e-69 233.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORY64609.1 - 1.5e-08 34.7 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PX-associated SASRP1 PF15160.6 ORY64609.1 - 3.9 7.1 6.0 7.8 6.1 6.0 1.4 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Ribosomal_L26 PF16906.5 ORY64610.1 - 1.7e-34 118.1 2.1 2.2e-34 117.8 2.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY64610.1 - 5.6e-10 38.8 5.5 1.4e-09 37.5 5.5 1.7 1 0 0 1 1 1 1 KOW motif HMGL-like PF00682.19 ORY64611.1 - 6.6e-79 265.2 0.2 1.1e-78 264.4 0.2 1.4 1 0 0 1 1 1 1 HMGL-like Acetyltransf_7 PF13508.7 ORY64612.1 - 3e-07 30.8 0.0 6.9e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY64612.1 - 0.00011 22.5 0.0 0.029 14.6 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY64612.1 - 0.00013 21.9 0.0 0.0012 18.8 0.0 2.2 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY64612.1 - 0.00085 19.3 0.0 0.0027 17.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY64612.1 - 0.17 11.9 0.0 1.1 9.3 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY64613.1 - 0.00067 20.0 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY64613.1 - 0.01 15.8 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_1 PF00583.25 ORY64613.1 - 0.063 13.5 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Pkinase PF00069.25 ORY64614.1 - 1.3e-61 208.3 0.0 1.5e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY64614.1 - 7.2e-35 120.5 0.0 1.2e-34 119.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY64614.1 - 0.0086 15.4 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY64614.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ORY64614.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY64614.1 - 0.12 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY64614.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRS4 PF10422.9 ORY64615.1 - 0.37 10.3 4.7 0.73 9.4 4.7 1.4 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Gpr1_Fun34_YaaH PF01184.19 ORY64617.1 - 2.8e-38 131.6 19.5 3.5e-38 131.3 19.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EHN PF06441.12 ORY64618.1 - 3.8e-30 104.4 0.1 6.7e-30 103.6 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY64618.1 - 4.5e-14 52.7 0.0 7.8e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.18 ORY64619.1 - 4.2e-05 23.6 12.9 7.8e-05 22.7 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY64619.1 - 0.0094 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pinin_SDK_memA PF04696.13 ORY64621.1 - 0.005 16.9 5.4 0.005 16.9 5.4 3.4 4 0 0 4 4 4 2 pinin/SDK/memA/ protein conserved region PH PF00169.29 ORY64622.1 - 0.016 15.7 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 PH domain Gag_p24 PF00607.20 ORY64622.1 - 0.079 12.8 0.8 0.15 11.9 0.8 1.5 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) CCDC84 PF14968.6 ORY64622.1 - 0.19 11.3 2.9 0.25 10.9 1.1 1.9 1 1 0 1 1 1 0 Coiled coil protein 84 DUF1640 PF07798.11 ORY64622.1 - 4.7 7.2 7.1 0.55 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) GDC-P PF02347.16 ORY64624.1 - 1.8e-186 620.2 0.0 4.4e-175 582.6 0.0 2.4 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 ORY64624.1 - 0.0028 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4974 PF16344.5 ORY64624.1 - 0.0032 17.4 0.1 4.4 7.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4974) FAD_binding_1 PF00667.20 ORY64625.1 - 1.5e-59 201.3 0.0 2.3e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 ORY64625.1 - 2.1e-08 34.8 0.0 6.2e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY64625.1 - 0.026 14.9 0.0 0.24 11.8 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain IU_nuc_hydro PF01156.19 ORY64626.1 - 2.5e-79 267.0 0.0 2.9e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase KTSC PF13619.6 ORY64627.1 - 0.064 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 KTSC domain Prok_Ub PF14454.6 ORY64627.1 - 0.16 11.6 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Glft2_N PF17994.1 ORY64628.1 - 0.014 15.4 0.2 0.03 14.2 0.1 1.6 2 0 0 2 2 2 0 Galactofuranosyltransferase 2 N-terminal Dscam_C PF12355.8 ORY64628.1 - 0.071 14.1 0.2 0.14 13.2 0.2 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal TP6A_N PF04406.14 ORY64629.1 - 4.7e-17 61.7 0.2 1.5e-16 60.2 0.1 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase CCDC24 PF15669.5 ORY64629.1 - 0.02 14.8 0.6 0.029 14.2 0.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family RRM_1 PF00076.22 ORY64630.1 - 2.1e-25 88.3 0.3 5.8e-17 61.3 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY64630.1 - 0.014 15.5 0.0 0.076 13.2 0.1 2.1 2 0 0 2 2 2 0 RNA recognition motif Limkain-b1 PF11608.8 ORY64630.1 - 0.02 15.0 0.2 1.4 9.0 0.1 2.9 2 1 0 2 2 2 0 Limkain b1 OB_RNB PF08206.11 ORY64630.1 - 8.4 6.2 5.4 1.3 8.7 0.3 2.3 3 0 0 3 3 3 0 Ribonuclease B OB domain Arb1 PF09692.10 ORY64632.1 - 2.9e-14 53.1 0.0 7.4e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Methyltransf_8 PF05148.15 ORY64635.1 - 1.6e-63 214.5 0.0 2e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_25 PF13649.6 ORY64635.1 - 1.9e-05 25.3 0.1 0.011 16.5 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY64635.1 - 7.8e-05 23.3 0.1 0.001 19.7 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY64635.1 - 0.0051 16.8 0.7 0.2 11.6 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 ORY64635.1 - 0.029 13.9 0.0 0.5 9.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY64635.1 - 0.072 13.8 0.0 16 6.3 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Bmt2 PF11968.8 ORY64635.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 SH3_1 PF00018.28 ORY64637.1 - 7.2e-27 92.7 0.2 1.4e-12 47.0 0.0 3.6 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 ORY64637.1 - 1.1e-15 57.2 0.9 5e-08 32.7 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 ORY64637.1 - 3.2e-15 55.5 0.3 5.7e-10 38.7 0.0 3.7 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 ORY64637.1 - 3.3e-07 30.3 0.0 6.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 PX domain Chitin_synth_1 PF01644.17 ORY64638.1 - 1.4e-64 217.0 0.0 2e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY64638.1 - 2.9e-27 94.4 0.0 5.8e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY64638.1 - 6e-20 71.4 0.1 1.5e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY64638.1 - 1.3e-05 25.2 2.7 1.3e-05 25.2 2.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY64638.1 - 0.15 11.9 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 F-box-like PF12937.7 ORY64730.1 - 0.00016 21.5 0.4 0.00043 20.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like HRXXH PF13933.6 ORY64731.1 - 6.8e-50 169.9 0.0 7.7e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 ORY64731.1 - 3.1e-09 37.5 0.0 4.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase TPR_16 PF13432.6 ORY64733.1 - 0.0005 20.7 0.5 0.0015 19.1 0.5 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY64733.1 - 0.0046 17.4 0.0 0.019 15.5 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY64733.1 - 0.53 11.3 6.0 4.9 8.2 2.9 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat RTC4 PF14474.6 ORY64734.1 - 1.9e-20 73.2 0.0 6.5e-20 71.5 0.0 2.0 1 0 0 1 1 1 1 RTC4-like domain DUF2408 PF10303.9 ORY64735.1 - 8.8e-54 181.7 0.1 1.8e-32 112.7 0.0 4.9 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) Peptidase_S9 PF00326.21 ORY64736.1 - 1.5e-50 171.6 0.1 2.3e-50 171.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 ORY64736.1 - 0.07 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat KAR9 PF08580.10 ORY64737.1 - 9.4e-11 41.0 30.0 9.4e-11 41.0 30.0 4.5 2 2 1 3 3 3 2 Yeast cortical protein KAR9 SOG2 PF10428.9 ORY64737.1 - 0.0011 18.3 7.3 0.0011 18.3 7.3 3.6 2 1 1 3 3 3 1 RAM signalling pathway protein GAS2 PF02187.17 ORY64737.1 - 0.021 14.9 0.1 0.045 13.8 0.1 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain ADH_N PF08240.12 ORY64738.1 - 3.7e-28 97.6 0.8 6.3e-28 96.8 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY64738.1 - 4.4e-09 36.4 0.1 5.6e-07 29.6 0.0 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 ORY64738.1 - 5.6e-09 35.8 0.4 1.3e-08 34.5 0.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 ORY64738.1 - 0.14 11.6 0.1 1.5 8.3 0.0 2.4 3 0 0 3 3 3 0 Glucose dehydrogenase C-terminus UPF0061 PF02696.14 ORY64740.1 - 8.8e-108 361.1 0.0 1.2e-107 360.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family dCMP_cyt_deam_1 PF00383.23 ORY64742.1 - 2.1e-11 43.6 0.1 3.2e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY64742.1 - 6.4e-09 35.7 0.0 8.9e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC2 PF18772.1 ORY64742.1 - 0.067 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 APOBEC3 PF18771.1 ORY64742.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 APOBEC3 SNAD4 PF18750.1 ORY64742.1 - 0.19 11.9 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 ABC_membrane PF00664.23 ORY64744.1 - 3.4e-59 200.7 27.1 1.1e-33 117.0 10.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY64744.1 - 2.1e-48 164.3 0.0 5.4e-27 95.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY64744.1 - 1.7e-10 40.8 0.1 0.00034 20.1 0.0 3.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY64744.1 - 1.3e-05 25.2 0.2 0.082 13.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY64744.1 - 2.6e-05 24.2 0.3 0.017 15.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 ORY64744.1 - 0.00029 21.4 1.7 0.35 11.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 ORY64744.1 - 0.0007 20.0 6.3 0.065 13.6 0.0 3.9 5 0 0 5 5 4 1 AAA ATPase domain AAA_29 PF13555.6 ORY64744.1 - 0.00073 19.2 2.6 0.21 11.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 ORY64744.1 - 0.0013 18.3 0.1 0.33 10.5 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region cobW PF02492.19 ORY64744.1 - 0.0022 17.6 0.2 0.0076 15.9 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ORY64744.1 - 0.0033 18.0 0.3 0.41 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 ORY64744.1 - 0.0084 15.9 0.0 2 8.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.25 ORY64744.1 - 0.011 15.4 0.2 0.66 9.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.6 ORY64744.1 - 0.014 15.3 0.4 5.8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 ORY64744.1 - 0.014 15.5 1.4 0.25 11.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 ORY64744.1 - 0.015 15.5 0.2 6.3 7.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 ORY64744.1 - 0.018 15.5 0.4 13 6.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 ORY64744.1 - 0.019 14.3 0.2 3.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.9 ORY64744.1 - 0.019 13.9 0.3 0.48 9.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 ORY64744.1 - 0.029 14.8 0.2 8.9 6.8 0.0 2.8 3 0 0 3 3 2 0 RNA helicase IstB_IS21 PF01695.17 ORY64744.1 - 0.036 13.8 0.6 11 5.7 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 ORY64744.1 - 0.036 13.6 0.3 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY64744.1 - 0.049 13.3 2.2 2.1 8.0 0.0 3.2 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY64744.1 - 0.051 13.6 0.3 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY64744.1 - 0.053 13.7 0.1 0.38 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain RecA PF00154.21 ORY64744.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein NACHT PF05729.12 ORY64744.1 - 0.1 12.5 0.8 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 ORY64744.1 - 0.23 11.7 1.9 6.9 6.9 0.1 2.9 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY64744.1 - 0.25 10.7 1.1 20 4.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 ORY64744.1 - 0.25 10.4 1.2 4.7 6.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 ORY64744.1 - 1.1 9.3 3.2 3.5 7.7 0.7 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain PLCC PF14466.6 ORY64745.1 - 0.15 12.2 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein NIR_SIR PF01077.22 ORY64746.1 - 2.3e-55 186.4 0.0 6.8e-49 165.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 ORY64746.1 - 2e-31 107.7 0.0 2.2e-15 56.3 0.0 2.8 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 ORY64746.1 - 1.7e-23 83.4 0.0 5.3e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin Trp_syntA PF00290.20 ORY64746.1 - 0.09 11.6 0.0 0.35 9.7 0.0 1.9 2 0 0 2 2 2 0 Tryptophan synthase alpha chain DUF604 PF04646.12 ORY64747.1 - 1.2e-10 41.3 0.1 3.6e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF604 MFS_1 PF07690.16 ORY64748.1 - 3.2e-42 144.7 31.2 1.3e-40 139.4 14.9 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY64748.1 - 0.00028 19.4 6.8 0.00028 19.4 6.8 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY64748.1 - 0.011 14.2 16.3 0.0042 15.5 9.8 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector SLC35F PF06027.12 ORY64749.1 - 5e-93 311.9 13.3 5.9e-93 311.7 13.3 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 ORY64749.1 - 1.3e-07 31.0 0.5 2.2e-07 30.1 0.5 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like IF4E PF01652.18 ORY64750.1 - 2.2e-37 128.3 0.0 3.4e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF155 PF02582.14 ORY64752.1 - 1.4e-42 145.7 0.0 1.9e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF3320 PF11784.8 ORY64752.1 - 0.1 12.6 0.5 0.31 11.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3320) SR-25 PF10500.9 ORY64752.1 - 0.52 9.9 6.2 0.82 9.2 6.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein LRR_4 PF12799.7 ORY64753.1 - 5.9e-13 48.8 12.7 0.0059 17.0 0.2 5.1 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY64753.1 - 2.8e-07 30.2 16.3 0.00011 21.9 5.5 4.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 ORY64753.1 - 0.0039 16.7 2.1 0.053 13.0 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 ORY64753.1 - 0.14 12.8 11.1 8.3 7.4 0.3 5.8 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY64753.1 - 4.2 7.7 16.4 14 6.0 0.3 5.6 5 0 0 5 5 5 0 Leucine Rich repeat UPF0086 PF01868.16 ORY64755.1 - 3e-27 94.4 0.0 5.2e-27 93.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 CoA_transf_3 PF02515.17 ORY64756.1 - 2.5e-62 211.2 0.0 9.7e-48 163.1 0.0 2.6 2 2 0 2 2 2 2 CoA-transferase family III EGF_2 PF07974.13 ORY64757.1 - 0.018 15.4 6.0 0.018 15.4 6.0 3.5 2 1 1 3 3 3 0 EGF-like domain cEGF PF12662.7 ORY64757.1 - 0.027 14.4 3.2 0.7 9.9 0.9 3.0 2 1 0 2 2 2 0 Complement Clr-like EGF-like TIL PF01826.17 ORY64757.1 - 1.5 9.1 21.2 3.3 8.0 2.1 2.6 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain NAT PF04768.13 ORY64759.1 - 6.9e-33 113.7 0.0 3e-20 72.6 0.0 2.3 2 0 0 2 2 2 2 NAT, N-acetyltransferase, of N-acetylglutamate synthase Rad51 PF08423.11 ORY64761.1 - 8.3e-09 35.1 0.5 8.3e-09 35.1 0.5 1.6 2 0 0 2 2 2 1 Rad51 HHH_5 PF14520.6 ORY64761.1 - 2.6e-07 31.1 1.8 3.8e-07 30.6 1.8 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 ORY64761.1 - 0.0046 16.8 0.1 0.0095 15.8 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 ORY64761.1 - 0.027 14.2 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain Rhodanese PF00581.20 ORY64762.1 - 6.6e-19 68.4 0.0 3.8e-11 43.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF1213 PF06740.12 ORY64762.1 - 0.08 13.5 0.3 0.08 13.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) NUDIX PF00293.28 ORY64763.1 - 4.3e-23 81.8 0.0 5.8e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S7 PF00177.21 ORY64764.1 - 9e-25 87.1 0.0 1.3e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Nmad3 PF18754.1 ORY64764.1 - 0.035 13.7 0.3 0.055 13.0 0.3 1.2 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 DUF3140 PF11338.8 ORY64764.1 - 0.041 14.3 0.1 0.069 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Zn_clus PF00172.18 ORY64765.1 - 0.072 13.2 9.2 2.3 8.4 3.3 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Elf1 PF05129.13 ORY64765.1 - 0.35 11.0 2.9 0.75 9.9 2.9 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DEAD PF00270.29 ORY64766.1 - 4e-36 124.4 0.0 5.9e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY64766.1 - 9e-28 96.8 0.0 2.3e-27 95.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY64766.1 - 2.2e-07 31.0 0.0 5.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DJ-1_PfpI PF01965.24 ORY64768.1 - 4.1e-14 52.7 0.0 5.2e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3262 PF11660.8 ORY64769.1 - 0.1 13.0 0.4 0.2 12.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) Plasmodium_Vir PF05795.11 ORY64769.1 - 0.72 9.2 2.6 1 8.7 2.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.11 ORY64769.1 - 6.2 5.0 13.1 8 4.6 13.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Urb2 PF10441.9 ORY64770.1 - 4e-41 141.2 0.0 6e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Urb2/Npa2 family ThrE PF06738.12 ORY64772.1 - 1.2e-51 175.4 9.7 1.2e-51 175.4 9.7 2.3 2 1 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY64772.1 - 1e-08 35.4 2.1 1e-08 35.4 2.1 3.2 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE Bac_rhodopsin PF01036.18 ORY64772.1 - 0.045 13.3 8.1 0.016 14.8 3.5 2.2 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein Zn_clus PF00172.18 ORY64773.1 - 2.9e-05 24.1 6.1 5e-05 23.3 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGS PF05002.15 ORY64774.1 - 1.4e-33 114.8 3.2 1.4e-33 114.8 3.2 1.6 2 0 0 2 2 2 1 SGS domain CS PF04969.16 ORY64774.1 - 2.4e-15 57.3 0.1 3.8e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 CS domain Maf PF02545.14 ORY64775.1 - 3.5e-44 150.6 0.0 4e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Aldedh PF00171.22 ORY64776.1 - 6.3e-15 54.6 4.5 4.9e-10 38.5 2.2 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family His_Phos_2 PF00328.22 ORY64777.1 - 1.3e-38 133.4 0.0 8.5e-38 130.7 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GTP_EFTU PF00009.27 ORY64778.1 - 1.2e-55 188.1 0.3 1.8e-55 187.5 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY64778.1 - 6e-19 68.4 0.0 1.2e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY64778.1 - 1.5e-16 60.5 3.1 1.5e-16 60.5 3.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY64778.1 - 2.7e-05 24.2 0.1 5.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY64778.1 - 0.019 14.9 0.1 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 ORY64778.1 - 0.027 14.0 0.6 0.053 13.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ORY64778.1 - 0.48 10.2 2.7 12 5.6 0.1 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation WD40 PF00400.32 ORY65615.1 - 1.4e-05 25.7 11.2 0.0025 18.6 1.6 5.3 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY65615.1 - 0.17 12.2 0.0 4.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORY65615.1 - 0.27 11.8 7.6 2.5 8.7 0.0 4.2 5 0 0 5 5 5 0 PQQ-like domain Hydrolase_4 PF12146.8 ORY65616.1 - 2.6e-13 49.8 0.0 2.2e-09 37.0 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY65616.1 - 1.3e-12 48.0 0.0 1.3e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ORY65616.1 - 5.7e-08 32.9 0.0 9.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase PF00151.19 ORY65616.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipase Abhydrolase_2 PF02230.16 ORY65616.1 - 0.021 14.6 1.0 0.9 9.3 0.1 2.4 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY65616.1 - 0.038 13.4 0.0 0.15 11.5 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF818 PF05677.12 ORY65616.1 - 0.083 11.8 0.0 0.17 10.8 0.0 1.4 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) Say1_Mug180 PF10340.9 ORY65616.1 - 0.083 11.7 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Steryl acetyl hydrolase DLH PF01738.18 ORY65616.1 - 0.096 12.2 0.0 15 5.1 0.0 2.7 3 0 0 3 3 3 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 ORY65616.1 - 0.14 11.1 0.0 0.51 9.2 0.0 1.9 2 1 0 2 2 2 0 Chlorophyllase enzyme SH3BGR PF04908.15 ORY65617.1 - 1.5e-08 34.7 0.3 5.4e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 ORY65617.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin Di19_C PF14571.6 ORY65618.1 - 0.038 14.5 2.9 0.038 14.5 2.9 3.7 2 2 2 4 4 4 0 Stress-induced protein Di19, C-terminal Myc_N PF01056.18 ORY65618.1 - 1.5 8.6 12.0 2.5 7.9 6.4 2.2 2 0 0 2 2 2 0 Myc amino-terminal region PRC2_HTH_1 PF18118.1 ORY65618.1 - 5 8.0 9.4 0.37 11.6 0.7 2.7 3 0 0 3 3 3 0 Polycomb repressive complex 2 tri-helical domain Pex16 PF08610.10 ORY65619.1 - 8.8e-112 373.4 0.0 1.1e-111 373.1 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) JAB PF01398.21 ORY65620.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ubiquitin PF00240.23 ORY65623.1 - 1.8e-34 117.3 0.5 3.3e-34 116.5 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 ORY65623.1 - 6.1e-26 90.3 1.0 6.1e-26 90.3 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 ORY65623.1 - 4e-16 58.6 0.6 7.8e-16 57.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY65623.1 - 2.2e-05 24.8 0.4 0.00014 22.2 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY65623.1 - 0.0008 19.5 0.3 0.0018 18.3 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY65623.1 - 0.006 16.9 0.4 0.013 15.9 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY65623.1 - 0.0064 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 ORY65623.1 - 0.0064 16.7 0.2 0.011 16.0 0.2 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DUF2407 PF10302.9 ORY65623.1 - 0.012 16.1 0.5 0.017 15.7 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY65623.1 - 0.022 14.8 1.1 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_L37e PF01907.19 ORY65624.1 - 4.1e-26 90.9 10.4 7.5e-26 90.0 10.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 ORY65624.1 - 0.0081 16.2 1.2 0.012 15.6 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 ORY65624.1 - 0.027 14.5 0.4 0.039 14.0 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C3HC4_2 PF13923.6 ORY65624.1 - 1.2 9.0 5.8 11 6.0 6.5 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY65624.1 - 1.6 8.7 6.1 2.6 8.0 6.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) VPS9 PF02204.18 ORY65625.1 - 9.4e-17 61.1 0.0 2.3e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain Dynein_light PF01221.18 ORY65626.1 - 9.2e-36 122.0 0.3 1e-35 121.9 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 ORY65626.1 - 0.18 12.5 0.0 0.23 12.1 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain Velvet PF11754.8 ORY65627.1 - 7.1e-30 104.8 11.0 5.1e-20 72.5 0.0 3.2 2 1 1 3 3 3 2 Velvet factor Tim17 PF02466.19 ORY65628.1 - 5.8e-23 81.4 9.3 1.4e-22 80.2 9.3 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-C2H2 PF00096.26 ORY65629.1 - 8.4e-21 73.2 54.3 0.00027 21.2 2.2 8.3 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY65629.1 - 1.4e-16 59.7 50.4 0.0013 19.4 2.8 8.2 8 0 0 8 8 8 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY65629.1 - 2.4e-14 53.0 50.4 1e-07 32.0 1.5 8.4 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY65629.1 - 6.8e-05 23.1 21.7 0.018 15.3 5.7 3.7 1 1 3 4 4 4 3 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY65629.1 - 0.0019 18.4 23.8 0.36 11.2 0.2 6.9 8 0 0 8 8 8 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY65629.1 - 0.015 15.6 7.0 0.015 15.6 7.0 4.2 3 3 2 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 ORY65629.1 - 0.029 14.8 1.6 0.029 14.8 1.6 5.4 3 1 2 5 5 5 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 ORY65629.1 - 0.38 11.0 13.5 0.72 10.1 0.5 3.5 3 0 0 3 3 3 0 TFIIH C1-like domain Mut7-C PF01927.16 ORY65629.1 - 0.48 10.5 6.8 0.1 12.7 2.4 2.1 2 1 0 2 2 2 0 Mut7-C RNAse domain zf-met PF12874.7 ORY65629.1 - 0.66 10.4 26.8 0.38 11.2 0.6 6.4 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zinc-ribbons_6 PF07191.12 ORY65629.1 - 0.68 10.0 9.4 13 5.9 4.4 3.3 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_3rep PF18868.1 ORY65629.1 - 1.1 9.9 13.5 0.48 11.1 0.9 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_9 PF14369.6 ORY65629.1 - 3.1 8.1 9.7 3.4 8.0 0.3 4.1 4 0 0 4 4 4 0 zinc-ribbon GAGA PF09237.11 ORY65629.1 - 3.6 7.5 9.7 11 5.9 0.5 4.2 2 1 2 4 4 4 0 GAGA factor zf-CHY PF05495.12 ORY65629.1 - 4 8.0 18.0 6.2 7.4 5.2 2.7 1 1 1 2 2 2 0 CHY zinc finger zinc_ribbon_15 PF17032.5 ORY65629.1 - 6.7 7.5 11.5 12 6.7 5.5 3.0 1 1 0 2 2 2 0 zinc-ribbon family Glyco_transf_22 PF03901.17 ORY65631.1 - 2.6e-53 181.7 11.5 3.6e-53 181.3 11.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family FAD_binding_3 PF01494.19 ORY65633.1 - 3.3e-19 69.3 0.1 3.3e-11 43.0 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY65633.1 - 1.1e-07 31.4 0.2 2.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY65633.1 - 1.4e-06 27.7 0.2 2.1e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY65633.1 - 2.9e-06 26.3 1.2 0.0012 17.7 0.4 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 ORY65633.1 - 4.1e-06 26.9 0.2 1.1e-05 25.5 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY65633.1 - 7.6e-06 25.7 1.7 0.0019 17.8 0.3 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY65633.1 - 0.0014 19.1 0.2 0.031 14.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY65633.1 - 0.0021 17.5 0.3 0.0037 16.7 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY65633.1 - 0.0026 16.9 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY65633.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ORY65633.1 - 0.04 13.2 0.0 0.078 12.2 0.0 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PrpF PF04303.13 ORY65633.1 - 0.18 10.7 0.0 5.1 6.0 0.0 2.1 2 0 0 2 2 2 0 PrpF protein MCRA PF06100.11 ORY65633.1 - 0.19 10.5 0.0 0.41 9.4 0.0 1.6 1 0 0 1 1 1 0 MCRA family Voltage_CLC PF00654.20 ORY65634.1 - 2.1e-85 287.1 30.0 3.4e-85 286.4 30.0 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 ORY65634.1 - 0.00027 21.3 0.1 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain Myco_arth_vir_N PF09610.10 ORY65634.1 - 0.37 10.9 1.9 1.6 8.9 1.9 2.1 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Mod_r PF07200.13 ORY65635.1 - 3.6e-31 108.2 7.7 4.4e-31 108.0 7.7 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein HMMR_C PF15908.5 ORY65635.1 - 0.023 15.0 0.5 0.044 14.1 0.5 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Svf1_C PF17187.4 ORY65636.1 - 1.2e-50 171.5 0.1 3.9e-50 169.9 0.0 1.8 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORY65636.1 - 6.1e-43 146.7 0.0 8.9e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Metallophos PF00149.28 ORY65637.1 - 8.2e-09 36.3 0.0 3.3e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 ORY65637.1 - 0.048 12.0 0.0 0.14 10.4 0.0 1.7 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase NOC3p PF07540.11 ORY65638.1 - 2.3e-22 79.3 0.0 5.8e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 ORY65638.1 - 1.3e-16 61.1 0.0 5.5e-16 59.1 0.0 2.2 1 0 0 1 1 1 1 CBF/Mak21 family Histone PF00125.24 ORY65638.1 - 7.4 7.0 12.9 0.21 11.9 2.4 2.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 AidB_N PF18158.1 ORY65639.1 - 1.4e-18 67.3 0.1 3.2e-18 66.2 0.0 1.6 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY65639.1 - 5.3e-18 65.7 0.2 1.7e-17 64.0 0.2 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY65639.1 - 1.2e-12 47.9 0.0 2.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY65639.1 - 0.001 19.7 0.0 0.003 18.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY65639.1 - 0.0038 17.5 0.5 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain TauD PF02668.16 ORY65640.1 - 3.5e-32 112.3 0.0 5.2e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORY65640.1 - 2.6e-08 34.4 0.0 6.1e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 ORY65640.1 - 0.033 13.3 0.0 0.098 11.7 0.0 1.7 2 0 0 2 2 2 0 CsiD COX5B PF01215.19 ORY65641.1 - 7.6e-38 129.1 0.0 8.9e-38 128.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zinc_ribbon_4 PF13717.6 ORY65641.1 - 0.037 14.0 0.3 0.077 12.9 0.2 1.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 ORY65641.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain MoCF_biosynth PF00994.24 ORY65642.1 - 6e-53 178.4 0.0 9.3e-28 96.7 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 ORY65642.1 - 4.3e-34 117.5 1.1 6.8e-34 116.9 1.1 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 ORY65642.1 - 1.5e-12 47.5 0.0 1.5e-12 47.5 0.0 3.0 4 0 0 4 4 4 1 MoeA C-terminal region (domain IV) K_channel_TID PF07941.11 ORY65642.1 - 3.5 8.2 11.9 7.4 7.1 11.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain IlvN PF07991.12 ORY65643.1 - 7.4e-48 162.2 0.1 1.3e-47 161.5 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORY65643.1 - 2.5e-22 79.7 0.0 1.8e-21 77.0 0.0 2.1 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Glyco_hydro_32N PF00251.20 ORY65647.1 - 8.5e-27 94.5 2.7 2e-21 76.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 ORY65647.1 - 6e-25 88.1 0.4 1.2e-24 87.2 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 ORY65647.1 - 0.0054 16.8 0.1 0.013 15.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) 3Beta_HSD PF01073.19 ORY65648.1 - 2.1e-62 210.7 0.0 5.4e-58 196.2 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY65648.1 - 2.2e-31 109.2 0.0 3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY65648.1 - 1.9e-15 57.1 0.0 5.7e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY65648.1 - 4.8e-13 49.4 0.0 7.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY65648.1 - 9.9e-09 34.7 0.0 1.1e-05 24.7 0.0 2.7 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 ORY65648.1 - 1.7e-07 30.6 0.0 2.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY65648.1 - 4.9e-06 25.9 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY65648.1 - 0.00011 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 ORY65648.1 - 0.043 13.7 0.3 2 8.3 0.1 2.5 1 1 1 2 2 2 0 KR domain Lipase_3 PF01764.25 ORY65649.1 - 7.1e-10 38.9 0.0 1.8e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) OPT PF03169.15 ORY65650.1 - 1.4e-141 473.2 26.3 1.6e-141 473.0 26.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 ORY65650.1 - 0.029 14.4 0.9 0.13 12.3 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S BacteriocIIc_cy PF12173.8 ORY65650.1 - 0.056 13.7 4.6 6.1 7.2 0.2 3.9 3 0 0 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like SLATT_1 PF18181.1 ORY65650.1 - 3.5 7.6 8.6 2.4 8.1 0.1 3.7 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 SLATT_2 PF18183.1 ORY65650.1 - 7.7 6.3 5.5 0.92 9.3 0.4 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 2 Beta_elim_lyase PF01212.21 ORY65651.1 - 2.9e-69 233.6 0.0 4.4e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORY65651.1 - 2.8e-06 26.7 0.0 3.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY65651.1 - 0.019 13.5 0.0 0.031 12.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY65651.1 - 0.026 13.5 0.1 0.043 12.8 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Arginase PF00491.21 ORY65652.1 - 1e-73 248.3 0.0 1.2e-73 248.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family RRM_1 PF00076.22 ORY65653.1 - 2.7e-15 55.9 0.0 4.4e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY65653.1 - 0.00026 21.0 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif Proteasome PF00227.26 ORY65654.1 - 2.4e-46 157.6 0.0 4.8e-46 156.7 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY65654.1 - 2.1e-13 49.6 0.1 3.6e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-Tim10_DDP PF02953.15 ORY65655.1 - 1.8e-19 69.1 0.1 2.1e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SKG6 PF08693.10 ORY65656.1 - 0.0042 16.5 2.7 0.0076 15.6 2.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SKG6 PF08693.10 ORY65657.1 - 0.00047 19.5 1.5 0.0011 18.3 1.5 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ribosomal_L35Ae PF01247.18 ORY65658.1 - 6.2e-42 141.7 1.8 6.9e-42 141.5 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY65658.1 - 0.032 14.4 0.1 8.1 6.7 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain Sugar_tr PF00083.24 ORY65659.1 - 1.1e-106 357.4 10.9 1.3e-106 357.2 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY65659.1 - 8.8e-31 107.1 31.7 1.1e-29 103.5 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY65659.1 - 7.5e-11 41.2 6.5 2.8e-10 39.3 1.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Vut_1 PF02592.15 ORY65659.1 - 0.00076 19.8 0.1 0.00076 19.8 0.1 2.3 3 0 0 3 3 3 1 Putative vitamin uptake transporter PTR2 PF00854.21 ORY65659.1 - 2.5 6.9 9.4 0.036 12.9 1.0 1.9 2 0 0 2 2 2 0 POT family PMI_typeI PF01238.21 ORY65660.1 - 1.4e-117 393.1 0.0 1.7e-117 392.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 ORY65660.1 - 0.038 13.7 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.19 ORY65660.1 - 0.17 11.7 0.0 9.8 6.1 0.0 2.8 3 0 0 3 3 3 0 AraC-like ligand binding domain She9_MDM33 PF05546.11 ORY65662.1 - 2.3e-68 229.9 4.5 2.3e-68 229.9 4.5 1.8 2 0 0 2 2 2 1 She9 / Mdm33 family CAP_N PF01213.19 ORY65662.1 - 0.5 9.8 21.3 0.17 11.3 5.7 2.9 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal UL42 PF17638.2 ORY65662.1 - 0.7 9.9 6.3 8.7 6.3 0.2 2.4 2 0 0 2 2 2 0 HCMV UL42 Mito_fiss_reg PF05308.11 ORY65662.1 - 1.1 9.3 14.8 1.1 9.3 0.8 2.7 3 0 0 3 3 3 0 Mitochondrial fission regulator Ribosomal_S4e PF00900.20 ORY65663.1 - 2.1e-37 126.9 1.5 2.6e-37 126.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY65663.1 - 9.6e-25 86.0 0.2 1.9e-24 85.0 0.2 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY65663.1 - 2.3e-20 72.4 6.4 4.1e-20 71.6 6.4 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORY65663.1 - 3.5e-07 29.8 0.0 8e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 ORY65663.1 - 1.8e-05 24.5 1.4 5.1e-05 23.1 0.6 2.2 2 0 0 2 2 2 1 KOW motif SNF2_N PF00176.23 ORY65664.1 - 8.9e-60 202.2 0.0 3e-59 200.5 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY65664.1 - 6.9e-17 61.8 0.0 3.7e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY65664.1 - 0.00056 19.9 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY65665.1 - 7.1e-15 55.2 0.0 1.2e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY65665.1 - 1.1e-13 51.6 0.0 2.4e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY65665.1 - 9.9e-05 22.6 0.0 0.00031 21.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 ORY65665.1 - 0.16 11.4 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein WD40 PF00400.32 ORY65666.1 - 3.1e-07 31.0 10.3 0.47 11.4 0.1 6.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY65666.1 - 0.00019 21.7 0.0 2.6 8.4 0.0 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain S-antigen PF05756.11 ORY65666.1 - 1.2 9.5 5.0 1 9.8 2.4 2.0 2 0 0 2 2 2 0 S-antigen protein PBP1_TM PF14812.6 ORY65666.1 - 5.8 7.4 10.1 7.7 7.0 0.8 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAICAR_synt PF01259.18 ORY65667.1 - 8.7e-89 297.4 0.0 1.1e-88 297.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase ING PF12998.7 ORY66625.1 - 5.5e-16 59.0 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY66625.1 - 8.4e-05 22.4 6.0 0.00014 21.6 6.0 1.4 1 0 0 1 1 1 1 PHD-finger TAP42 PF04177.12 ORY66625.1 - 0.0078 15.4 2.1 0.0078 15.4 2.1 2.2 3 1 1 4 4 4 1 TAP42-like family zf-HC5HC2H PF13771.6 ORY66625.1 - 0.021 15.1 0.2 0.042 14.1 0.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 ORY66625.1 - 0.23 11.1 2.6 0.42 10.2 2.6 1.4 1 0 0 1 1 1 0 PHD-finger CAP_N PF01213.19 ORY66625.1 - 5.3 6.4 6.1 1.4 8.3 2.8 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Frataxin_Cyay PF01491.16 ORY66626.1 - 5e-39 132.7 0.0 5.6e-39 132.6 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain RHH_3 PF12651.7 ORY66626.1 - 0.017 15.0 0.5 0.043 13.8 0.1 1.8 2 0 0 2 2 2 0 Ribbon-helix-helix domain HTH_34 PF13601.6 ORY66627.1 - 0.0045 17.1 0.1 0.015 15.5 0.0 1.9 2 0 0 2 2 2 1 Winged helix DNA-binding domain F-box-like PF12937.7 ORY66627.1 - 0.021 14.7 0.1 0.093 12.6 0.1 2.2 1 0 0 1 1 1 0 F-box-like Aminotran_1_2 PF00155.21 ORY66630.1 - 1.3e-52 179.2 0.0 2.7e-52 178.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY66630.1 - 8.6e-05 21.9 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Helicase_C PF00271.31 ORY66632.1 - 2.9e-20 72.7 0.0 5.4e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY66632.1 - 1.3e-19 70.8 0.0 2.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY66632.1 - 1.6e-15 57.3 0.0 3.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Rotamase PF00639.21 ORY66632.1 - 0.35 11.9 1.1 17 6.5 0.3 3.1 3 0 0 3 3 3 0 PPIC-type PPIASE domain TFIIE-A_C PF11521.8 ORY66632.1 - 9.8 6.6 8.7 51 4.3 3.4 3.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Catalase PF00199.19 ORY66633.1 - 6.4e-24 84.8 0.1 6.3e-21 74.9 0.1 2.1 1 1 0 1 1 1 1 Catalase Clp1 PF06807.14 ORY66634.1 - 1.9e-27 96.0 0.0 3.3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_P PF16575.5 ORY66634.1 - 2.8e-26 92.5 0.1 3.8e-18 66.0 0.0 3.0 2 1 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 ORY66634.1 - 1e-24 86.6 0.0 1.6e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor PduV-EutP PF10662.9 ORY66634.1 - 5.9e-05 22.8 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 ORY66634.1 - 0.00069 19.7 0.1 0.41 10.7 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY66634.1 - 0.001 19.4 0.1 0.0055 17.0 0.2 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORY66634.1 - 0.0047 17.4 0.0 0.0088 16.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORY66634.1 - 0.011 16.2 0.1 0.027 14.9 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 ORY66634.1 - 0.013 15.1 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Roc PF08477.13 ORY66634.1 - 0.028 14.6 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 ORY66634.1 - 0.029 13.7 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Septin DUF815 PF05673.13 ORY66634.1 - 0.051 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 ORY66634.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORY66634.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY66634.1 - 0.077 12.9 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 ORY66634.1 - 0.088 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORY66634.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 ORY66634.1 - 0.2 11.2 0.1 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TPR_9 PF13371.6 ORY66635.1 - 2.4e-06 27.6 0.2 9.5e-06 25.7 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY66635.1 - 5.7e-06 26.0 0.1 0.0015 18.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY66635.1 - 9.1e-06 25.3 0.0 0.096 12.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY66635.1 - 0.0099 16.5 0.0 0.073 13.7 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY66635.1 - 0.03 14.0 0.0 1.7 8.4 0.0 3.1 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.6 ORY66635.1 - 0.31 11.7 0.0 0.31 11.7 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PhoLip_ATPase_C PF16212.5 ORY66637.1 - 1.4e-74 251.0 33.1 2.4e-74 250.3 33.1 1.4 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY66637.1 - 3.5e-23 81.1 0.1 9.7e-23 79.6 0.1 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORY66637.1 - 8.4e-14 52.4 0.2 3.4e-06 27.5 0.0 3.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY66637.1 - 7.7e-12 45.1 0.0 1.8e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY66637.1 - 4.9e-06 26.2 0.1 4.9e-06 26.2 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY66637.1 - 0.00013 21.8 0.2 0.0035 17.1 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3371 PF11851.8 ORY66637.1 - 0.18 12.9 7.7 0.55 11.3 7.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Cpn60_TCP1 PF00118.24 ORY66638.1 - 5.3e-157 523.4 2.8 6.6e-157 523.1 2.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIA_gamma_N PF02268.16 ORY66640.1 - 1.3e-21 76.3 0.0 1.9e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 ORY66640.1 - 2.3e-19 69.2 0.1 3.8e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Catalase PF00199.19 ORY66641.1 - 1.2e-159 531.6 0.0 1.5e-159 531.2 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY66641.1 - 5.4e-20 71.4 0.4 1.1e-19 70.3 0.4 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 ORY66641.1 - 1.9e-08 34.1 0.0 9.1e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 ORY66641.1 - 0.00021 21.1 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Metallophos PF00149.28 ORY66642.1 - 3.5e-17 63.6 1.5 6.1e-17 62.8 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 ORY66642.1 - 1.9e-14 54.3 2.0 1.9e-14 54.3 2.0 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 ORY66642.1 - 1.9e-14 54.0 3.4 4.5e-14 52.8 3.4 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 ORY66642.1 - 0.0026 18.2 0.2 0.007 16.9 0.2 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pkinase PF00069.25 ORY66643.1 - 1.4e-40 139.4 0.0 3.1e-30 105.4 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY66643.1 - 2.6e-12 46.6 0.0 1.4e-10 40.9 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY66643.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY66643.1 - 0.00045 20.2 0.0 0.00081 19.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY66643.1 - 0.00089 18.7 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY66643.1 - 0.23 11.0 0.0 7.6 6.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 ORY66644.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S19e PF01090.19 ORY66645.1 - 6.7e-57 191.0 0.1 7.6e-57 190.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e zf-C2H2_jaz PF12171.8 ORY66646.1 - 3.4 8.1 6.8 2.9 8.3 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pyridox_ox_2 PF12900.7 ORY66647.1 - 3.5e-24 85.4 0.0 4.7e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Polysacc_deac_1 PF01522.21 ORY66648.1 - 1e-27 96.5 0.0 1.6e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase PepSY_2 PF13670.6 ORY66648.1 - 0.07 13.1 0.1 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain eIF-1a PF01176.19 ORY66649.1 - 1.7e-18 66.2 0.1 2.4e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Zn_ribbon_17 PF17120.5 ORY66651.1 - 7.3e-12 44.7 18.0 7.3e-12 44.7 18.0 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 ORY66651.1 - 0.005 17.7 21.4 0.41 11.6 0.4 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 ORY66651.1 - 0.014 15.7 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 RWD domain zf-rbx1 PF12678.7 ORY66651.1 - 0.1 12.9 15.2 0.26 11.6 15.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 ORY66651.1 - 3.4 7.8 15.5 6 7.1 1.2 3.0 2 1 1 3 3 3 0 KIAA1045 RING finger Mito_carr PF00153.27 ORY66652.1 - 6.4e-60 199.1 6.4 8.5e-20 70.5 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY66652.1 - 0.017 14.3 0.7 3 6.9 0.1 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Ten_N PF06484.12 ORY66652.1 - 0.26 11.1 0.7 0.47 10.3 0.7 1.3 1 0 0 1 1 1 0 Teneurin Intracellular Region Menin PF05053.13 ORY66653.1 - 1 7.7 6.2 1.1 7.6 6.2 1.0 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 ORY66653.1 - 3.5 6.3 4.4 3.6 6.3 4.4 1.1 1 0 0 1 1 1 0 Presenilin Phosphoesterase PF04185.14 ORY66654.1 - 8.3e-31 107.5 3.4 1.3e-30 106.8 3.4 1.3 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 ORY66655.1 - 3.8e-41 139.8 9.7 1.2e-40 138.2 0.8 3.6 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY66655.1 - 1.2e-39 135.1 9.9 1.3e-36 125.3 0.5 3.8 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY66655.1 - 1.5e-34 119.4 0.1 4.8e-34 117.8 0.1 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cupredoxin_1 PF13473.6 ORY66655.1 - 0.068 13.3 0.0 13 6.0 0.0 3.5 3 1 0 3 3 3 0 Cupredoxin-like domain NDT80_PhoG PF05224.12 ORY66656.1 - 1.7e-11 44.7 0.0 6e-11 42.9 0.0 1.9 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Kisspeptin PF15152.6 ORY66656.1 - 0.59 11.0 4.0 3.3 8.6 0.0 3.7 2 1 1 3 3 3 0 Kisspeptin WD40 PF00400.32 ORY66658.1 - 2e-26 91.7 0.8 4.3e-06 27.3 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY66658.1 - 7.4e-10 39.0 0.7 0.00084 19.6 0.6 4.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY66658.1 - 3e-05 24.0 2.2 0.0014 18.5 0.2 2.5 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY66658.1 - 3.8e-05 22.8 1.4 0.097 11.6 0.6 2.5 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY66658.1 - 7.3e-05 21.6 1.0 0.0038 15.9 0.5 3.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Gmad1 PF10647.9 ORY66658.1 - 0.00025 20.9 0.1 0.0027 17.5 0.1 2.1 2 0 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nucleoporin_N PF08801.11 ORY66658.1 - 0.0025 16.7 0.0 1.3 7.7 0.0 2.8 1 1 1 3 3 3 2 Nup133 N terminal like F-box-like PF12937.7 ORY66659.1 - 0.0082 16.0 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY66659.1 - 0.19 12.2 1.5 1.9 9.0 0.5 2.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) F_actin_cap_B PF01115.17 ORY66662.1 - 1.1e-94 316.6 0.0 1.3e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 ORY66662.1 - 0.005 16.3 0.0 0.17 11.3 0.0 2.6 2 1 0 2 2 2 1 F-actin capping protein alpha subunit DUF4596 PF15363.6 ORY66662.1 - 0.085 13.1 0.2 0.21 11.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) DUF1295 PF06966.12 ORY66663.1 - 1.3e-43 149.2 0.1 4.1e-43 147.6 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY66663.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family zf-H2C2_2 PF13465.6 ORY66664.1 - 1.1e-11 44.6 3.5 1.7e-08 34.5 0.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY66664.1 - 2.4e-06 27.7 0.5 2.4e-06 27.7 0.5 3.6 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY66664.1 - 0.00037 21.1 9.2 0.73 10.5 1.1 3.3 1 1 2 3 3 3 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY66664.1 - 0.00054 20.6 7.1 0.0059 17.3 0.3 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY66664.1 - 0.0013 18.7 1.2 0.007 16.3 0.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 ORY66664.1 - 0.012 16.0 0.7 4.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY66664.1 - 1.3 8.9 0.0 1.3 8.9 0.0 3.0 5 0 0 5 5 5 0 zinc-finger C2H2-type NUC173 PF08161.12 ORY66665.1 - 8.3e-58 195.4 0.3 1.8e-55 187.8 0.0 2.8 3 0 0 3 3 3 2 NUC173 domain Tti2 PF10521.9 ORY66665.1 - 0.02 14.4 0.0 5.3 6.5 0.0 3.3 3 0 0 3 3 3 0 Tti2 family HEAT PF02985.22 ORY66665.1 - 0.08 13.2 2.6 0.26 11.7 0.1 3.4 4 0 0 4 4 4 0 HEAT repeat MMS19_C PF12460.8 ORY66665.1 - 1.1 8.3 9.7 4.8 6.2 2.3 2.9 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Rot1 PF10681.9 ORY66773.1 - 7.7e-56 188.9 0.6 9.5e-56 188.6 0.6 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal CgtA PF06306.11 ORY66773.1 - 0.12 11.8 0.1 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) Methyltransf_2 PF00891.18 ORY66774.1 - 4.8e-22 78.3 0.0 9.4e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 ORY66774.1 - 0.00027 20.9 0.1 0.00068 19.6 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.14 ORY66774.1 - 0.003 17.1 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY66774.1 - 0.018 15.8 0.0 0.041 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORY66774.1 - 0.05 13.4 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_31 PF13847.6 ORY66774.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MarR_2 PF12802.7 ORY66774.1 - 0.073 13.0 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 MarR family GidB PF02527.15 ORY66774.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HTH_IclR PF09339.10 ORY66774.1 - 0.092 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_12 PF08242.12 ORY66774.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.11 ORY66774.1 - 0.12 13.0 0.0 0.23 12.2 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_2 PF00891.18 ORY66775.1 - 8.4e-18 64.4 0.0 1.9e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 ORY66775.1 - 2.7e-06 27.3 0.1 6.9e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain RPA_C PF08784.11 ORY66775.1 - 0.0055 17.3 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Replication protein A C terminal Rrf2 PF02082.20 ORY66775.1 - 0.028 14.8 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_16 PF10294.9 ORY66775.1 - 0.031 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase RNA_pol_Rpc34 PF05158.12 ORY66775.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit MTS PF05175.14 ORY66775.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain TnsD PF15978.5 ORY66775.1 - 0.21 10.6 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D MBF1 PF08523.10 ORY66776.1 - 2.1e-13 50.5 0.6 3.6e-13 49.7 0.6 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 ORY66777.1 - 2.9e-07 30.4 0.0 5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.10 ORY66777.1 - 8.8e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_31 PF13560.6 ORY66777.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Pirin PF02678.16 ORY66777.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Pirin Aldo_ket_red PF00248.21 ORY66779.1 - 1.1e-45 156.2 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.7 ORY66780.1 - 0.0024 17.7 0.4 0.0086 16.0 0.4 2.0 1 0 0 1 1 1 1 F-box-like COX16 PF14138.6 ORY66781.1 - 3e-31 107.7 0.1 3.8e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 OppC_N PF12911.7 ORY66781.1 - 0.041 13.8 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF1757 PF08560.10 ORY66784.1 - 0.0074 16.4 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1757) Trp_oprn_chp PF09534.10 ORY66784.1 - 0.0085 15.9 0.5 0.012 15.4 0.5 1.2 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) BLACT_WH PF17778.1 ORY66784.1 - 0.048 13.6 0.2 0.19 11.7 0.1 1.9 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain GAF_3 PF13492.6 ORY66786.1 - 6.8e-10 39.4 0.0 0.0031 17.8 0.0 3.4 2 1 0 2 2 2 2 GAF domain GAF PF01590.26 ORY66786.1 - 4.9e-07 30.4 0.0 0.012 16.2 0.0 2.5 2 0 0 2 2 2 2 GAF domain CAP_GLY PF01302.25 ORY66787.1 - 4.3e-16 58.7 0.0 1.1e-15 57.4 0.0 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 ORY66787.1 - 2.1e-11 43.6 2.2 0.00012 21.6 0.0 3.7 1 1 4 5 5 5 4 Leucine-rich repeat LRR_4 PF12799.7 ORY66787.1 - 9.2e-09 35.5 31.3 0.00043 20.6 3.1 5.6 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY66787.1 - 1.2e-08 34.6 26.8 0.00023 20.9 4.8 5.6 3 2 3 6 6 6 4 Leucine rich repeat LRR_2 PF07723.13 ORY66787.1 - 0.049 14.3 4.5 1.5 9.6 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Nucleotid_trans PF03407.16 ORY66788.1 - 5.5e-12 46.1 0.2 1.1e-11 45.1 0.2 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TauD PF02668.16 ORY66789.1 - 5.8e-37 127.9 0.0 8.4e-37 127.4 0.0 1.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DIOX_N PF14226.6 ORY66792.1 - 7.7e-18 65.4 0.0 1.5e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY66792.1 - 3e-16 59.8 0.0 5.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HTH_28 PF13518.6 ORY66792.1 - 0.048 13.8 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain COX16 PF14138.6 ORY66793.1 - 3.3e-31 107.6 0.1 4.2e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 OppC_N PF12911.7 ORY66793.1 - 0.042 13.8 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C F-box-like PF12937.7 ORY66794.1 - 9.2e-06 25.5 0.2 1.8e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY66794.1 - 0.18 11.7 2.6 0.36 10.7 0.5 2.6 2 1 0 2 2 2 0 F-box domain Svf1_C PF17187.4 ORY66794.1 - 0.28 11.0 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain R3H PF01424.22 ORY66795.1 - 2.5e-07 30.6 0.3 6e-07 29.3 0.1 1.7 2 0 0 2 2 2 1 R3H domain RRM_1 PF00076.22 ORY66795.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_N PF08240.12 ORY66796.1 - 8.1e-31 106.1 2.6 1.6e-30 105.2 2.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY66796.1 - 1.7e-25 89.5 0.0 3.5e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY66796.1 - 2.7e-11 43.4 0.7 3.7e-11 42.9 0.7 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 ORY66796.1 - 0.021 14.9 0.1 0.048 13.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N_2 PF13602.6 ORY66796.1 - 0.085 13.9 0.0 0.14 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ThiF PF00899.21 ORY66796.1 - 0.15 11.3 0.4 0.33 10.3 0.4 1.5 1 0 0 1 1 1 0 ThiF family Arrestin_C PF02752.22 ORY66797.1 - 4.9e-06 27.0 0.0 0.0024 18.3 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain WD40 PF00400.32 ORY66798.1 - 5.2e-19 68.2 4.8 1.6e-05 25.5 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY66798.1 - 1.2e-11 44.7 0.0 0.0019 18.4 0.0 4.3 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY66798.1 - 3.8e-08 32.4 0.0 2.8e-05 23.0 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY66798.1 - 0.0013 17.5 0.0 0.52 9.0 0.0 2.9 3 1 0 3 3 3 2 Nup133 N terminal like Itfg2 PF15907.5 ORY66798.1 - 0.13 11.3 0.0 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Ig_GlcNase PF18368.1 ORY66798.1 - 0.13 12.4 0.0 2.8 8.1 0.0 2.8 3 0 0 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain Hira PF07569.11 ORY66798.1 - 0.15 11.7 0.0 0.95 9.1 0.0 2.1 2 0 0 2 2 2 0 TUP1-like enhancer of split Striatin PF08232.12 ORY66799.1 - 1.4e-42 145.9 0.0 1.4e-42 145.9 0.0 4.6 3 1 1 4 4 4 1 Striatin family Pkinase PF00069.25 ORY66800.1 - 1.8e-74 250.5 0.0 2.2e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY66800.1 - 1.7e-34 119.3 0.0 2.2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY66800.1 - 1e-11 44.7 0.0 1.4e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY66800.1 - 6.1e-07 28.6 0.0 1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY66800.1 - 2.6e-05 23.7 0.1 8e-05 22.1 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY66800.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family NtA PF03146.15 ORY66800.1 - 0.02 14.7 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 Agrin NtA domain Brix PF04427.18 ORY66804.1 - 7.1e-39 133.9 0.0 5.8e-38 130.9 0.0 2.0 1 1 0 1 1 1 1 Brix domain Mito_carr PF00153.27 ORY66806.1 - 5.4e-25 87.1 0.3 6.1e-10 38.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein p450 PF00067.22 ORY66807.1 - 4.6e-14 52.0 0.0 7e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 ORY66808.1 - 5.4e-23 81.7 0.0 8.1e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY66808.1 - 3e-09 36.5 0.0 3.7e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase GTP-bdg_M PF16360.5 ORY66808.1 - 4.7 7.9 5.7 1.4 9.5 0.1 2.6 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Pyridoxal_deC PF00282.19 ORY66809.1 - 7.8e-18 64.3 0.0 1.8e-17 63.1 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SH2_2 PF14633.6 ORY66812.1 - 1.8e-72 243.3 0.0 1.8e-72 243.3 0.0 2.4 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.6 ORY66812.1 - 2.1e-33 114.8 0.0 4.3e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 ORY66812.1 - 2.3e-29 102.2 0.1 6.5e-29 100.7 0.1 1.8 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 ORY66812.1 - 5.1e-20 71.8 0.0 2.2e-18 66.5 0.0 2.5 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 ORY66812.1 - 7.5e-13 48.9 25.2 7.5e-13 48.9 25.2 5.3 5 0 0 5 5 5 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 ORY66812.1 - 1.4e-05 25.9 0.3 1.4e-05 25.9 0.3 2.9 2 0 0 2 2 2 1 HHH domain HHH_3 PF12836.7 ORY66812.1 - 0.00016 21.9 0.0 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_N PF09371.10 ORY66812.1 - 0.011 15.5 0.9 0.088 12.5 0.9 2.5 1 1 0 1 1 1 0 Tex-like protein N-terminal domain Condensation PF00668.20 ORY66813.1 - 1.7e-06 27.0 0.0 3.4e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Condensation domain AATase PF07247.12 ORY66813.1 - 1.2e-05 24.1 0.0 6.2e-05 21.7 0.0 1.9 2 1 0 2 2 2 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 ORY66813.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ribonucleas_3_3 PF14622.6 ORY66815.1 - 1.7e-06 28.2 0.0 0.0042 17.3 0.0 2.7 3 0 0 3 3 3 2 Ribonuclease-III-like dsrm PF00035.26 ORY66815.1 - 0.00015 22.4 0.0 0.00039 21.1 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 ORY66815.1 - 0.069 13.8 0.0 0.18 12.5 0.0 1.8 1 1 0 1 1 1 0 Ribonuclease III domain PDEase_II PF02112.15 ORY66816.1 - 1.3e-38 133.0 0.0 9e-38 130.2 0.0 2.1 2 1 0 2 2 2 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 ORY66816.1 - 0.00087 18.9 0.0 0.0033 17.0 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain F-box-like PF12937.7 ORY66817.1 - 3.2e-05 23.7 1.2 7.7e-05 22.5 1.2 1.7 1 0 0 1 1 1 1 F-box-like AMP-binding PF00501.28 ORY66818.1 - 4.5e-81 272.6 0.0 5.8e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY66818.1 - 1e-05 26.4 1.2 3e-05 24.9 1.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_9 PF08221.11 ORY66820.1 - 2.4e-08 34.0 1.5 0.00015 21.8 0.3 3.5 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 ORY66820.1 - 1.3e-07 31.6 0.0 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 ORY66820.1 - 0.0007 19.4 0.0 0.34 10.8 0.0 3.1 3 0 0 3 3 3 2 TFIIE alpha subunit SUIM_assoc PF16619.5 ORY66916.1 - 0.078 13.1 13.5 0.18 11.9 3.6 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 IFT57 PF10498.9 ORY66916.1 - 1.7 7.5 7.4 0.24 10.3 0.9 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 NIF PF03031.18 ORY66918.1 - 1.2e-25 90.2 0.0 5e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 ORY66918.1 - 3.4e-08 33.3 0.7 8.1e-08 32.1 0.7 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORY66918.1 - 6.6e-08 32.8 0.0 4.3e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY66918.1 - 0.0012 19.2 0.0 0.0022 18.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Biotin_lipoyl_2 PF13533.6 ORY66918.1 - 0.099 12.5 0.2 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like LIG3_BRCT PF16759.5 ORY66918.1 - 0.17 12.2 1.5 0.39 11.0 1.5 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain FMO-like PF00743.19 ORY66919.1 - 2.7e-15 55.8 0.0 7.2e-13 47.8 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY66919.1 - 1e-12 47.9 0.0 9.7e-10 38.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY66919.1 - 4.7e-10 39.7 1.5 8.9e-08 32.3 0.0 3.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY66919.1 - 5e-09 36.3 0.0 1.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY66919.1 - 5e-08 32.9 0.2 4.6e-05 23.2 0.4 3.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY66919.1 - 4.2e-06 26.2 0.0 2.4e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY66919.1 - 2.9e-05 23.4 0.0 0.0015 17.7 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORY66919.1 - 0.005 16.1 0.5 0.2 10.8 0.3 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 ORY66919.1 - 0.013 14.8 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 ORY66919.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 ORY66919.1 - 0.027 13.3 0.5 0.047 12.5 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 ORY66919.1 - 0.057 14.0 3.0 0.096 13.3 0.8 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY66919.1 - 0.066 12.3 0.8 5.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY66919.1 - 0.13 11.6 1.0 0.18 11.1 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 ORY66919.1 - 0.19 11.3 0.4 5.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HI0933_like PF03486.14 ORY66919.1 - 0.25 10.0 1.0 2.3 6.8 1.0 2.3 3 0 0 3 3 3 0 HI0933-like protein DUF2635 PF10948.8 ORY66920.1 - 0.021 14.6 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) SCO1-SenC PF02630.14 ORY66921.1 - 9.9e-46 155.0 0.0 1.4e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 ORY66921.1 - 0.0024 17.8 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ORY66921.1 - 0.084 13.2 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like NDUF_B7 PF05676.13 ORY66922.1 - 4.1e-26 90.5 0.6 4.9e-26 90.2 0.6 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ank_2 PF12796.7 ORY66923.1 - 7.9e-19 68.0 0.1 1.3e-09 38.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY66923.1 - 1.3e-18 67.1 3.9 4.3e-09 36.7 0.1 4.6 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY66923.1 - 2.2e-14 53.1 0.1 4.4e-06 26.9 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY66923.1 - 1.6e-13 50.6 1.0 3.1e-05 24.2 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY66923.1 - 5.9e-12 44.7 0.1 9.3e-05 22.6 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 ORY66923.1 - 2.1e-05 24.3 0.7 0.00041 20.2 0.0 3.0 2 2 0 2 2 2 1 KilA-N domain Ribosomal_60s PF00428.19 ORY66923.1 - 3.4 8.3 14.6 15 6.3 14.6 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Yae1_N PF09811.9 ORY66924.1 - 1.6e-09 37.3 0.1 3.2e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal VHS PF00790.19 ORY66925.1 - 7.3e-22 77.7 0.0 1.4e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 ORY66925.1 - 0.00051 20.3 0.2 0.0011 19.2 0.2 1.6 1 0 0 1 1 1 1 GAT domain UBN_AB PF14075.6 ORY66925.1 - 0.39 10.4 8.0 0.79 9.4 8.0 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain Peptidase_S49_N PF08496.10 ORY66925.1 - 2.1 8.4 9.9 0.45 10.6 5.9 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal BUD22 PF09073.10 ORY66926.1 - 1.2 8.4 12.0 1.8 7.8 12.0 1.4 1 1 0 1 1 1 0 BUD22 Thiolase_N PF00108.23 ORY66927.1 - 1.3e-21 77.1 3.4 2.4e-18 66.4 0.1 2.9 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY66927.1 - 1.7e-10 40.6 0.6 1.3e-09 37.8 0.0 2.7 3 0 0 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 ORY66927.1 - 0.00028 20.7 2.5 0.018 14.9 0.9 2.6 2 1 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SpoVAD PF07451.11 ORY66927.1 - 0.0042 15.8 0.8 0.011 14.5 0.1 1.9 2 0 0 2 2 2 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.26 ORY66927.1 - 0.026 14.1 4.5 0.95 9.0 0.6 2.8 2 1 1 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY66927.1 - 0.034 14.2 0.5 0.18 11.8 0.0 2.5 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain PGAP1 PF07819.13 ORY66928.1 - 9.1e-77 257.9 0.0 1.3e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY66928.1 - 3.6e-07 31.0 0.8 3.6e-07 31.0 0.8 2.8 3 1 0 3 3 3 1 Alpha/beta hydrolase family DUF676 PF05057.14 ORY66928.1 - 4.4e-05 23.1 0.1 8.3e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ORY66928.1 - 0.0035 16.7 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY66928.1 - 0.0049 16.6 0.0 0.0093 15.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 ORY66928.1 - 0.027 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 ORY66928.1 - 0.036 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Complex1_LYR PF05347.15 ORY66929.1 - 8.6e-06 25.7 1.1 2.1e-05 24.5 1.1 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY66929.1 - 0.053 14.3 0.6 0.15 12.8 0.6 1.8 1 0 0 1 1 1 0 Complex1_LYR-like Lactonase PF10282.9 ORY66930.1 - 1.3e-26 93.7 0.0 4.1e-26 92.1 0.0 1.9 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ORY66930.1 - 0.0072 15.9 0.1 0.2 11.2 0.0 2.9 3 0 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORY66930.1 - 0.034 14.3 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Arylesterase DUF563 PF04577.14 ORY66931.1 - 9e-19 68.4 0.0 1.3e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) WLM PF08325.10 ORY66933.1 - 1.6e-50 171.9 0.0 2.3e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 ORY66933.1 - 0.0014 17.9 15.7 0.05 12.9 5.2 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others Aspzincin_M35 PF14521.6 ORY66933.1 - 0.2 12.2 0.0 0.41 11.2 0.0 1.4 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase DZR PF12773.7 ORY66933.1 - 1.5 8.9 6.9 3.8 7.6 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Vps36-NZF-N PF16988.5 ORY66933.1 - 8.6 5.8 12.9 0.59 9.6 1.8 3.2 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Phosphorylase PF00343.20 ORY66934.1 - 3e-296 984.5 0.0 3.6e-296 984.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3417 PF11897.8 ORY66934.1 - 0.017 15.6 1.5 0.58 10.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) Carn_acyltransf PF00755.20 ORY66937.1 - 2.4e-184 614.3 0.0 3.1e-184 613.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase NGP1NT PF08153.12 ORY66937.1 - 6.9e-49 165.3 0.9 2.2e-48 163.7 0.2 2.2 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 ORY66937.1 - 5.8e-18 65.0 0.0 8.6e-15 54.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY66937.1 - 0.0002 21.3 0.0 0.00068 19.6 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 ORY66937.1 - 0.00074 19.1 0.0 0.0029 17.1 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 ORY66937.1 - 0.019 14.4 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.23 ORY66937.1 - 0.63 10.1 3.5 7.5 6.6 0.0 3.7 3 1 1 4 4 4 0 Dynamin family tRNA-synt_2 PF00152.20 ORY66938.1 - 8.6e-78 261.6 0.0 1.1e-77 261.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY66938.1 - 1.4e-06 28.2 0.1 2.5e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SRP-alpha_N PF04086.13 ORY66938.1 - 0.014 15.3 6.7 0.022 14.7 6.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal tRNA-synt_2d PF01409.20 ORY66938.1 - 0.033 13.7 0.3 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF4746 PF15928.5 ORY66938.1 - 0.068 12.6 5.9 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Hamartin PF04388.12 ORY66938.1 - 0.17 10.5 6.1 0.33 9.6 5.8 1.6 2 0 0 2 2 2 0 Hamartin protein WD40 PF00400.32 ORY66939.1 - 9.6e-42 140.2 15.4 1.1e-07 32.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY66939.1 - 1.7e-17 63.5 0.0 0.00081 19.6 0.1 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY66939.1 - 4e-05 23.6 0.0 0.048 13.5 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY66939.1 - 0.0003 20.2 0.0 0.039 13.3 0.0 3.1 2 1 2 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 ORY66939.1 - 0.069 11.7 0.0 0.15 10.6 0.0 1.6 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ret2_MD PF18528.1 ORY66939.1 - 0.088 13.2 0.0 13 6.2 0.0 2.9 3 0 0 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Na_H_Exchanger PF00999.21 ORY66940.1 - 5.9e-18 64.8 30.2 2e-13 49.9 18.9 2.8 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family PH_4 PF15404.6 ORY66941.1 - 8.4e-22 77.8 0.2 5.4e-19 68.7 0.0 2.9 2 1 1 3 3 3 2 Pleckstrin homology domain Ribosom_S12_S23 PF00164.25 ORY66942.1 - 1.4e-35 121.4 1.3 1.7e-35 121.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_49 PF13896.6 ORY66943.1 - 6e-32 111.3 0.0 5.5e-22 78.6 0.0 3.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF3328 PF11807.8 ORY66943.1 - 7.7 6.2 6.0 0.7 9.6 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) RCC1 PF00415.18 ORY66944.1 - 1.7e-22 79.8 7.1 0.00088 19.8 0.1 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY66944.1 - 2.1e-08 33.7 5.2 0.024 14.5 0.0 5.8 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat zf-C5HC2 PF02928.16 ORY66944.1 - 1.7 9.1 8.9 1.8 9.0 5.2 2.4 2 0 0 2 2 2 0 C5HC2 zinc finger ubiquitin PF00240.23 ORY66945.1 - 1.5e-170 553.2 25.4 1.9e-33 114.0 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 ORY66945.1 - 2.6e-78 257.8 27.8 4.3e-15 55.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY66945.1 - 3e-28 98.1 12.9 0.00064 20.1 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY66945.1 - 1.7e-19 69.6 5.6 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY66945.1 - 1.2e-17 64.0 4.5 0.16 12.1 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY66945.1 - 2.6e-17 62.9 12.0 0.063 13.6 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 ORY66945.1 - 5.6e-16 59.0 2.3 0.49 11.0 0.0 5.2 1 1 1 5 5 5 5 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY66945.1 - 3.7e-12 46.4 0.7 1.8 8.4 0.0 5.1 1 1 4 5 5 5 5 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 ORY66945.1 - 3.7e-09 36.2 1.8 1.4 8.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 ORY66945.1 - 1.2e-07 31.7 32.7 21 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_7 PF17957.1 ORY66945.1 - 1.6e-07 32.0 0.6 41 5.0 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF2870 PF11069.8 ORY66945.1 - 1.9e-07 31.4 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) TmoB PF06234.12 ORY66945.1 - 4.7e-07 29.8 0.1 40 4.4 0.0 5.8 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) DUF3861 PF12977.7 ORY66945.1 - 5.8e-07 29.6 5.6 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 ORY66945.1 - 1.2e-06 28.2 6.5 15 5.5 0.0 5.3 5 0 0 5 5 5 0 ACT domain UDP-g_GGTase PF06427.11 ORY66945.1 - 4.3e-06 26.8 6.0 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 ORY66945.1 - 2.3e-05 23.9 0.1 29 4.0 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 ORY66945.1 - 6e-05 23.5 2.2 97 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF493 PF04359.14 ORY66945.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 ORY66945.1 - 0.0007 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 ORY66945.1 - 0.008 16.3 8.5 85 3.4 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FlgD_ig PF13860.6 ORY66945.1 - 0.052 13.4 13.5 57 3.7 0.1 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Tash_PEST PF07708.11 ORY66945.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 ORY66945.1 - 0.47 11.0 12.5 1e+02 3.5 0.1 4.9 1 1 1 3 3 3 0 Phage tail sheath protein beta-sandwich domain YcgR_2 PF12945.7 ORY66945.1 - 2.4 8.4 7.6 3.2e+02 1.6 0.0 4.8 5 0 0 5 5 5 0 Flagellar protein YcgR PI3K_p85B PF02192.16 ORY66945.1 - 3 7.6 12.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Cnl2_NKP2 PF09447.10 ORY66945.1 - 3.1 8.0 14.4 1.3e+02 2.8 0.1 5.3 5 0 0 5 5 5 0 Cnl2/NKP2 family protein Ribosomal_S4e PF00900.20 ORY66945.1 - 5.8 6.9 11.7 1.7e+02 2.2 0.1 5.6 5 0 0 5 5 5 0 Ribosomal family S4e RTA1 PF04479.13 ORY66946.1 - 4.7e-64 215.8 6.8 4.7e-64 215.8 6.8 1.7 2 0 0 2 2 2 1 RTA1 like protein PsbW PF07123.12 ORY66946.1 - 0.6 10.1 2.7 0.31 11.1 0.2 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Chorismate_synt PF01264.21 ORY66947.1 - 5.2e-140 465.8 0.0 6e-140 465.6 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Sugar_tr PF00083.24 ORY66948.1 - 2.3e-86 290.4 19.3 2.8e-86 290.2 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY66948.1 - 3e-18 65.9 28.5 1.6e-17 63.5 25.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_85 PF03644.13 ORY66949.1 - 3.3e-85 286.2 0.0 4.7e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 dCMP_cyt_deam_1 PF00383.23 ORY66951.1 - 6.6e-24 83.7 0.2 1.8e-23 82.3 0.2 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY66951.1 - 1.5e-19 70.1 0.1 9.3e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 ORY66951.1 - 1.9e-05 24.7 1.2 0.00024 21.2 1.2 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 ORY66951.1 - 0.18 12.0 0.1 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Peptidase_M24 PF00557.24 ORY66952.1 - 4.2e-49 167.1 0.0 5.6e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY66952.1 - 3.9e-40 136.4 0.0 6.3e-40 135.7 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SHOCT PF09851.9 ORY66952.1 - 0.17 11.7 0.1 0.42 10.4 0.1 1.7 1 0 0 1 1 1 0 Short C-terminal domain F-box PF00646.33 ORY66954.1 - 0.03 14.2 0.2 0.071 13.0 0.2 1.6 1 0 0 1 1 1 0 F-box domain SLC35F PF06027.12 ORY66955.1 - 1.8e-86 290.4 16.0 2.2e-86 290.1 16.0 1.1 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 ORY66955.1 - 6.5e-12 45.0 0.2 6.5e-12 45.0 0.2 1.6 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 ORY66955.1 - 5.3e-07 29.1 1.7 7.7e-07 28.6 1.2 1.5 2 0 0 2 2 2 1 UAA transporter family Mg_trans_NIPA PF05653.14 ORY66955.1 - 0.00083 18.5 0.9 0.0019 17.4 0.9 1.6 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY66955.1 - 1.7 8.8 23.2 0.052 13.7 6.3 2.5 2 1 0 2 2 2 0 EamA-like transporter family Adaptin_N PF01602.20 ORY66956.1 - 9.7e-112 374.2 1.6 1.8e-111 373.3 1.6 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 ORY66956.1 - 4e-58 195.8 0.3 7.9e-58 194.9 0.3 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 ORY66956.1 - 1.8e-34 118.3 0.0 6.7e-34 116.5 0.0 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 ORY66956.1 - 1.7e-16 60.4 4.4 8.9e-10 38.8 0.0 5.2 4 2 3 7 7 7 4 HEAT repeats Cnd1 PF12717.7 ORY66956.1 - 2.9e-06 27.4 9.1 0.08 13.0 0.6 4.9 4 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY66956.1 - 0.0037 17.4 8.6 2 8.9 0.1 5.9 7 0 0 7 7 7 1 HEAT repeat RTP1_C1 PF10363.9 ORY66956.1 - 0.13 12.5 1.7 38 4.5 0.1 3.8 2 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 ORY66956.1 - 0.14 12.9 4.7 19 6.3 0.0 5.8 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat zf-C2H2 PF00096.26 ORY66957.1 - 3.8e-11 42.8 14.7 9.3e-06 25.8 2.1 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY66957.1 - 1.2e-07 32.2 5.5 0.0007 20.2 0.1 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY66957.1 - 2.8e-06 27.7 13.7 0.00045 20.8 1.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY66957.1 - 7e-06 26.2 2.6 7e-06 26.2 2.6 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY66957.1 - 0.0022 18.2 6.2 0.011 16.0 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY66957.1 - 0.0035 17.6 1.7 0.008 16.5 1.7 1.6 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 ORY66957.1 - 0.0054 17.1 4.0 0.057 13.8 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 ORY66957.1 - 0.0071 17.0 3.2 0.011 16.4 3.2 1.3 1 1 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 ORY66957.1 - 0.022 14.8 0.9 0.022 14.8 0.9 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_S78 PF04586.17 ORY66957.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Caudovirus prohead serine protease zf-C2H2_2 PF12756.7 ORY66957.1 - 0.44 10.9 8.1 7.5 6.9 5.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zap1_zf2 PF18217.1 ORY66957.1 - 0.52 10.4 0.3 0.52 10.4 0.3 3.0 3 0 0 3 3 3 0 Zap1 zinc finger 2 zf_C2H2_ZHX PF18387.1 ORY66957.1 - 0.53 10.0 6.8 6.1 6.6 0.1 3.0 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Pkinase PF00069.25 ORY66958.1 - 2.2e-45 155.1 0.0 1.1e-44 152.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY66958.1 - 1.5e-23 83.4 0.0 2.4e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY66958.1 - 0.0039 17.2 0.2 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY66958.1 - 0.097 11.4 0.3 0.31 9.7 0.0 1.9 3 0 0 3 3 3 0 Fungal protein kinase Haspin_kinase PF12330.8 ORY66958.1 - 0.32 9.9 1.0 0.39 9.6 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Ndc1_Nup PF09531.10 ORY66958.1 - 0.45 9.2 5.3 0.84 8.3 5.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC_membrane PF00664.23 ORY66959.1 - 7.5e-66 222.6 30.8 5.4e-38 131.2 13.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY66959.1 - 3.6e-49 166.8 0.0 9e-26 91.0 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY66959.1 - 7.2e-13 48.5 0.0 1.2e-05 24.8 0.0 3.7 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY66959.1 - 2.5e-07 31.2 0.7 0.0074 16.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY66959.1 - 9.3e-07 28.9 1.5 0.051 13.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY66959.1 - 1.5e-06 28.2 1.1 0.039 14.0 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY66959.1 - 5.7e-05 22.8 0.9 0.2 11.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORY66959.1 - 0.00017 21.7 7.7 0.0032 17.5 0.2 3.2 3 0 0 3 3 3 2 Dynamin family AAA_7 PF12775.7 ORY66959.1 - 0.0013 18.3 0.3 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 ORY66959.1 - 0.0014 18.4 0.1 2.3 7.9 0.1 2.9 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY66959.1 - 0.0024 17.8 1.8 0.37 10.7 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ORY66959.1 - 0.0034 17.7 0.4 3 8.1 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 ORY66959.1 - 0.0039 16.9 2.0 1.8 8.2 0.0 2.6 3 0 0 3 3 2 2 AAA ATPase domain DUF87 PF01935.17 ORY66959.1 - 0.0044 17.1 2.5 0.62 10.1 0.3 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Roc PF08477.13 ORY66959.1 - 0.0079 16.4 0.2 6.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ORY66959.1 - 0.0091 15.4 0.6 0.98 8.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 ORY66959.1 - 0.013 15.1 0.1 0.32 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain S_4TM PF18159.1 ORY66959.1 - 0.013 14.8 0.7 0.97 8.7 0.0 2.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain NACHT PF05729.12 ORY66959.1 - 0.014 15.3 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 ORY66959.1 - 0.015 15.1 0.9 1.7 8.4 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 ORY66959.1 - 0.021 13.8 0.8 0.36 9.8 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 ORY66959.1 - 0.023 14.0 0.7 0.83 8.9 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 ORY66959.1 - 0.024 13.7 0.1 0.77 8.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 ORY66959.1 - 0.029 14.9 0.0 7.8 7.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY66959.1 - 0.034 14.1 0.3 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 ORY66959.1 - 0.04 13.1 2.3 0.87 8.7 0.1 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORY66959.1 - 0.042 14.3 0.1 15 6.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 ORY66959.1 - 0.047 14.1 0.5 19 5.7 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.18 ORY66959.1 - 0.054 13.2 0.4 0.89 9.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IIGP PF05049.13 ORY66959.1 - 0.07 12.2 1.9 3.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_23 PF13476.6 ORY66959.1 - 0.15 12.6 12.5 0.61 10.5 0.1 3.7 4 0 0 4 4 3 0 AAA domain RHS_repeat PF05593.14 ORY66959.1 - 0.15 12.6 0.1 0.5 10.9 0.1 1.9 1 0 0 1 1 1 0 RHS Repeat cobW PF02492.19 ORY66959.1 - 0.2 11.2 1.2 1.5 8.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 ORY66959.1 - 0.27 10.9 1.8 27 4.5 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein NB-ARC PF00931.22 ORY66959.1 - 0.37 10.0 1.1 13 4.8 0.3 2.6 2 0 0 2 2 2 0 NB-ARC domain EI24 PF07264.11 ORY66959.1 - 0.41 10.9 22.1 0.01 16.1 6.3 3.0 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) Aldo_ket_red PF00248.21 ORY66961.1 - 2.6e-38 131.9 0.0 5.9e-36 124.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family 7TMR-DISMED2 PF07696.11 ORY66961.1 - 0.00018 21.5 0.0 0.019 15.0 0.0 2.3 1 1 1 2 2 2 2 7TMR-DISM extracellular 2 SH3_1 PF00018.28 ORY66962.1 - 5.5e-16 57.9 0.0 8.1e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY66962.1 - 8.4e-10 38.2 0.0 1.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY66962.1 - 9.1e-10 38.2 0.1 1.4e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain hSH3 PF14603.6 ORY66962.1 - 0.0067 16.8 0.0 0.01 16.3 0.0 1.2 1 0 0 1 1 1 1 Helically-extended SH3 domain SH3_3 PF08239.11 ORY66962.1 - 0.098 12.9 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Cation_efflux PF01545.21 ORY66963.1 - 5.4e-28 98.1 7.9 7.6e-28 97.6 7.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY66963.1 - 3e-06 27.3 0.1 6.2e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Ccdc124 PF06244.12 ORY66964.1 - 0.00034 21.2 0.3 0.0004 20.9 0.3 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Pkinase PF00069.25 ORY67929.1 - 1.2e-21 77.3 0.0 1.2e-19 70.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY67929.1 - 3.7e-18 65.8 0.0 4.3e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY67929.1 - 0.0016 17.9 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY67929.1 - 0.0053 16.7 0.0 0.25 11.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY67929.1 - 0.015 14.6 0.0 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 ORY67929.1 - 0.04 12.9 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PAP_assoc PF03828.19 ORY67933.1 - 6.9e-18 64.6 0.2 2.4e-17 62.9 0.2 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY67933.1 - 2.6e-11 43.6 0.3 1e-10 41.8 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ORY67933.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain NARP1 PF12569.8 ORY67933.1 - 1.9 7.3 7.9 3.3 6.5 7.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ABC1 PF03109.16 ORY67934.1 - 1.2e-34 119.0 0.0 1.9e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 ORY67934.1 - 3.4e-06 26.8 0.0 7.1e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 ORY67934.1 - 0.012 15.0 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.23 ORY67934.1 - 0.091 12.7 2.1 1.8 8.4 0.3 3.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family PRIMA1 PF16101.5 ORY67934.1 - 0.92 9.6 0.0 0.92 9.6 0.0 2.6 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Nse4_C PF08743.10 ORY67935.1 - 7.8e-27 93.4 0.0 7.8e-27 93.4 0.0 2.4 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 ORY67935.1 - 7.8e-17 61.1 0.7 2.8e-16 59.4 0.7 2.0 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF613 PF04764.12 ORY67935.1 - 0.078 13.1 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF613) DUF604 PF04646.12 ORY67936.1 - 1e-16 61.1 0.1 1.7e-16 60.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 ORY67936.1 - 2.1e-05 24.1 0.1 4e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Fringe-like NmrA PF05368.13 ORY67937.1 - 0.00084 19.0 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family SPRY PF00622.28 ORY67939.1 - 1.3e-19 70.5 1.4 1.1e-10 41.6 0.6 2.3 2 0 0 2 2 2 2 SPRY domain CLTH PF10607.9 ORY67939.1 - 4.1e-15 56.0 0.0 6.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY67939.1 - 0.015 15.2 0.2 0.015 15.2 0.2 1.9 2 0 0 2 2 2 0 LisH HRXXH PF13933.6 ORY67941.1 - 7.7e-73 245.1 0.2 1.1e-72 244.6 0.2 1.2 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 ORY67941.1 - 1.8e-05 25.3 1.8 1.8e-05 25.3 1.8 2.9 3 1 0 3 3 3 1 Lysine-specific metallo-endopeptidase MFS_1 PF07690.16 ORY67942.1 - 2.4e-28 99.1 37.3 4.9e-28 98.1 37.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 ORY67943.1 - 7e-30 104.1 38.0 8.5e-18 64.4 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF485 PF04341.12 ORY67943.1 - 0.029 14.3 0.1 0.029 14.3 0.1 4.9 4 1 1 5 5 5 0 Protein of unknown function, DUF485 Sugar_tr PF00083.24 ORY67943.1 - 0.18 10.6 28.2 0.049 12.5 12.1 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter Mobilization_B PF17511.2 ORY67943.1 - 2.1 8.7 4.9 2.1 8.7 0.4 2.7 3 0 0 3 3 3 0 Mobilization protein B Ost5 PF05251.12 ORY67944.1 - 4.2e-16 59.0 9.7 4.8e-16 58.8 9.7 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 FAM76 PF16046.5 ORY67945.1 - 9.9 5.4 13.3 5.1 6.4 8.4 2.4 2 0 0 2 2 2 0 FAM76 protein Piwi PF02171.17 ORY67946.1 - 2.2e-84 283.3 0.0 2.8e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 ORY67946.1 - 4.2e-12 45.6 0.0 1.1e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 ORY67946.1 - 8.7e-12 45.1 0.0 2.3e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute PAZ PF02170.22 ORY67946.1 - 1.6e-09 37.6 0.0 3.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 ORY67946.1 - 6.7e-09 36.5 0.0 1.4e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 ORY67946.1 - 2.2e-06 27.9 0.0 5.9e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain F-box-like PF12937.7 ORY67947.1 - 1.5e-10 40.8 2.5 4.1e-10 39.4 2.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY67947.1 - 6.8e-07 29.0 0.5 1.8e-06 27.7 0.5 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 ORY67947.1 - 3.2e-05 24.6 0.3 0.0012 19.7 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat Aldose_epim PF01263.20 ORY67949.1 - 2e-45 155.4 0.0 5.2e-45 154.0 0.0 1.6 1 1 0 1 1 1 1 Aldose 1-epimerase TIP120 PF08623.10 ORY67950.1 - 1.3e-59 200.7 9.0 6.2e-58 195.3 0.5 4.5 4 1 0 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT PF02985.22 ORY67950.1 - 1.4e-12 46.7 18.8 3.1 8.3 0.1 12.8 14 0 0 14 14 13 2 HEAT repeat HEAT_2 PF13646.6 ORY67950.1 - 8.4e-12 45.3 24.8 0.03 14.7 0.0 9.4 8 2 2 11 11 9 4 HEAT repeats HEAT_EZ PF13513.6 ORY67950.1 - 4.4e-10 39.8 13.4 13 6.4 0.0 11.2 9 2 1 10 10 10 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY67950.1 - 3.6e-07 30.7 0.2 7.6 7.2 0.0 6.1 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 ORY67950.1 - 1.6e-05 25.1 8.1 0.28 11.4 0.0 7.6 7 2 0 7 7 7 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 ORY67950.1 - 5.8e-05 23.0 6.0 0.73 9.8 0.0 6.7 6 2 1 7 7 7 1 UME (NUC010) domain V-ATPase_H_C PF11698.8 ORY67950.1 - 0.00021 21.4 2.7 3.5 7.8 0.0 5.8 5 1 1 6 6 6 1 V-ATPase subunit H CLASP_N PF12348.8 ORY67950.1 - 0.0003 20.4 7.9 0.0016 18.1 0.0 4.8 5 1 0 5 5 5 1 CLASP N terminal RIX1 PF08167.12 ORY67950.1 - 0.00046 20.0 19.2 0.32 10.7 0.1 6.7 5 2 2 7 7 7 3 rRNA processing/ribosome biogenesis TAF6_C PF07571.13 ORY67950.1 - 0.0062 16.8 0.9 2.7 8.4 0.0 4.3 4 0 0 4 4 3 1 TAF6 C-terminal HEAT repeat domain Telomere_reg-2 PF10193.9 ORY67950.1 - 0.009 16.4 12.7 0.013 15.9 0.2 5.4 5 1 1 6 6 5 1 Telomere length regulation protein Cnd3 PF12719.7 ORY67950.1 - 0.03 13.5 2.6 11 5.1 0.0 4.2 3 2 1 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF3361 PF11841.8 ORY67950.1 - 0.071 13.0 5.7 16 5.4 0.1 4.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) DmsC PF04976.12 ORY67950.1 - 0.69 9.3 2.4 2.8 7.4 0.1 2.6 2 0 0 2 2 2 0 DMSO reductase anchor subunit (DmsC) ParcG PF10274.9 ORY67950.1 - 1.2 9.3 3.7 1.4e+02 2.5 0.0 4.7 5 0 0 5 5 5 0 Parkin co-regulated protein DUF2975 PF11188.8 ORY67951.1 - 5.8 6.8 10.7 3.1 7.7 5.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Homeodomain PF00046.29 ORY67953.1 - 3.5e-15 55.6 3.0 3.5e-15 55.6 3.0 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY67953.1 - 0.02 14.8 1.4 0.048 13.6 0.1 2.3 2 0 0 2 2 2 0 Homeobox KN domain Pyr_redox_2 PF07992.14 ORY67954.1 - 9.8e-31 107.1 0.0 1.3e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY67954.1 - 4.6e-11 43.1 0.6 3.2e-07 30.8 0.0 3.0 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY67954.1 - 0.052 12.4 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Piwi PF02171.17 ORY67955.1 - 3.8e-82 275.9 0.0 5.2e-82 275.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 ORY67955.1 - 4.1e-10 39.6 0.0 8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 ORY67955.1 - 6.7e-10 39.1 0.0 2.1e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 ORY67955.1 - 3e-08 33.9 1.4 8.2e-08 32.5 0.1 2.4 3 0 0 3 3 3 1 Argonaute linker 2 domain ArgoL1 PF08699.10 ORY67955.1 - 0.00021 20.9 0.0 0.00057 19.5 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain Piwi PF02171.17 ORY67956.1 - 1.6e-83 280.5 0.0 2.1e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 ORY67956.1 - 4.2e-10 39.7 0.0 1.8e-09 37.7 0.0 2.1 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 ORY67956.1 - 3.4e-08 33.7 0.8 9.8e-08 32.2 0.1 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain Piwi PF02171.17 ORY67957.1 - 5.2e-55 186.8 0.1 6.1e-55 186.6 0.1 1.0 1 0 0 1 1 1 1 Piwi domain Piwi PF02171.17 ORY67958.1 - 6.4e-21 74.9 1.1 7.4e-21 74.7 1.1 1.0 1 0 0 1 1 1 1 Piwi domain Glyco_transf_15 PF01793.16 ORY67959.1 - 5.1e-85 285.6 0.1 6.2e-85 285.3 0.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase FDF PF09532.10 ORY67960.1 - 1.8e-06 28.7 0.0 1.8e-06 28.7 0.0 2.4 1 1 1 2 2 2 1 FDF domain SM-ATX PF14438.6 ORY67960.1 - 0.0028 17.7 0.1 0.0055 16.8 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain SMG1_N PF17229.2 ORY67960.1 - 0.0094 16.7 1.2 0.0094 16.7 1.2 2.1 2 0 0 2 2 2 1 Serine/threonine-protein kinase SMG1 N-terminal LSM14 PF12701.7 ORY67960.1 - 0.02 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Scd6-like Sm domain Spt20 PF12090.8 ORY67960.1 - 0.56 9.8 10.2 0.99 9.0 10.2 1.4 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 ORY67960.1 - 2.2 7.0 5.4 2.6 6.7 5.4 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 ORY67960.1 - 3.3 8.7 6.5 9.5 7.3 6.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) G-gamma PF00631.22 ORY67961.1 - 7.9e-24 83.5 0.0 9e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain Nkap_C PF06047.11 ORY67962.1 - 2.6e-44 149.5 6.1 2.6e-44 149.5 6.1 2.2 2 1 1 3 3 3 1 NF-kappa-B-activating protein C-terminal domain SR-25 PF10500.9 ORY67962.1 - 0.0058 16.3 46.7 0.0058 16.3 46.7 2.7 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Band_7 PF01145.25 ORY67963.1 - 7.3e-23 81.5 2.9 1.2e-22 80.8 2.3 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 ORY67963.1 - 0.00012 21.3 2.9 0.00016 20.9 2.9 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Totivirus_coat PF05518.11 ORY67965.1 - 1.1 7.2 5.6 1.5 6.8 5.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein Hist_deacetyl PF00850.19 ORY68031.1 - 2.9e-73 247.0 0.0 4.2e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain GlutR_dimer PF00745.20 ORY68032.1 - 0.062 13.7 0.1 0.22 12.0 0.1 1.9 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain SpoIISA_toxin PF14171.6 ORY68033.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system YfhO PF09586.10 ORY68033.1 - 6.2 4.9 6.4 0.63 8.2 1.0 1.7 1 1 1 2 2 2 0 Bacterial membrane protein YfhO Beta_helix PF13229.6 ORY68034.1 - 1.6e-07 31.3 21.7 1.4e-05 25.0 20.7 3.1 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 ORY68034.1 - 0.011 15.0 12.0 0.087 12.1 10.9 2.8 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) MFS_1 PF07690.16 ORY68036.1 - 6e-18 64.9 25.6 3.5e-11 42.6 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY68036.1 - 0.07 12.0 5.6 0.46 9.3 0.6 2.7 3 0 0 3 3 3 0 MFS_1 like family NMO PF03060.15 ORY68037.1 - 2.2e-54 185.1 1.3 4.7e-54 184.0 1.3 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY68037.1 - 1.5e-10 40.7 2.6 1.1e-09 37.8 1.5 2.4 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY68037.1 - 2.4e-07 30.1 3.5 3.8e-07 29.5 3.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY68037.1 - 0.0092 15.1 1.9 0.018 14.2 1.9 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 ORY68037.1 - 0.023 13.9 0.3 0.033 13.4 0.3 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase O-FucT PF10250.9 ORY68038.1 - 2.1e-17 63.8 0.0 3.5e-17 63.1 0.0 1.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MRP-L47 PF06984.13 ORY68039.1 - 1.9e-24 85.6 1.6 3.3e-24 84.8 1.6 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 ORY68039.1 - 0.00087 19.2 1.6 0.003 17.5 1.6 1.9 1 1 0 1 1 1 1 Ribosomal L29 protein Nodulin_late PF07127.11 ORY68040.1 - 4.5 7.7 12.4 3.9 7.9 0.2 3.3 3 0 0 3 3 3 0 Late nodulin protein Arf PF00025.21 ORY68041.1 - 2.8e-18 66.0 0.0 4.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY68041.1 - 1.8e-05 24.4 0.0 6.4e-05 22.6 0.0 1.7 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY68041.1 - 2e-05 24.6 0.0 0.0072 16.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 ORY68041.1 - 0.00069 19.5 0.2 0.52 10.0 0.1 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein G-alpha PF00503.20 ORY68041.1 - 0.0024 17.1 0.1 0.47 9.6 0.0 2.6 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 ORY68041.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 ORY68041.1 - 0.016 15.3 0.1 0.054 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 ORY68041.1 - 0.021 14.2 0.2 0.31 10.4 0.2 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY68041.1 - 0.054 13.9 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 ORY68041.1 - 0.064 12.2 0.0 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 ORY68041.1 - 0.11 12.9 0.0 0.93 9.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY68041.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.22 ORY68041.1 - 0.21 11.2 0.0 0.64 9.6 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ferric_reduct PF01794.19 ORY68042.1 - 3.2e-22 79.0 4.3 1.6e-21 76.7 4.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY68042.1 - 5.3e-22 78.6 0.0 9.2e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY68042.1 - 2.8e-09 37.0 0.0 5.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY68042.1 - 0.00086 19.9 0.0 0.036 14.7 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4149 PF13664.6 ORY68042.1 - 2.8 8.3 6.2 17 5.8 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) XhlA PF10779.9 ORY68042.1 - 5.3 7.3 8.2 3.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Haemolysin XhlA DUF2298 PF10060.9 ORY68043.1 - 0.0092 14.7 4.4 0.013 14.3 4.4 1.1 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) SpoIISA_toxin PF14171.6 ORY68043.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2157 PF09925.9 ORY68043.1 - 1.7 8.4 11.8 16 5.2 6.1 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF983 PF06170.12 ORY68043.1 - 7.9 7.0 14.6 0.31 11.5 1.9 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF983) HVSL PF09749.9 ORY68045.1 - 6.8e-49 166.5 0.0 8.2e-49 166.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein Peptidase_M20 PF01546.28 ORY68046.1 - 1.9e-25 89.8 0.0 6.4e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 ORY68046.1 - 3e-14 53.2 13.3 0.00042 21.1 0.1 6.8 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 ORY68046.1 - 2.3e-09 37.1 0.0 4.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 ORY68046.1 - 0.011 14.5 0.0 0.12 11.0 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF2298 PF10060.9 ORY68047.1 - 0.0077 15.0 4.4 0.01 14.6 4.4 1.1 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) SpoIISA_toxin PF14171.6 ORY68047.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2157 PF09925.9 ORY68047.1 - 0.71 9.7 11.2 6.5 6.5 5.6 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) RRXRR PF14239.6 ORY68050.1 - 3.7 7.4 22.2 0.022 14.6 6.8 2.3 2 0 0 2 2 2 0 RRXRR protein PRP3 PF08572.10 ORY68050.1 - 4.8 6.8 28.7 0.26 11.0 3.2 2.9 2 1 1 3 3 3 0 pre-mRNA processing factor 3 (PRP3) PBP_N PF17093.5 ORY68051.1 - 0.085 13.1 0.1 0.085 13.1 0.1 2.5 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus ClpS PF02617.17 ORY68052.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS MFS_1 PF07690.16 ORY68053.1 - 4.4e-18 65.3 51.8 5.6e-17 61.7 50.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1195 PF06708.11 ORY68053.1 - 0.066 13.0 1.4 21 4.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1195) Pox_A14 PF05767.12 ORY68053.1 - 3.7 7.8 9.5 0.89 9.7 0.4 3.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Porin_3 PF01459.22 ORY68055.1 - 3.5e-74 249.7 5.4 4e-74 249.5 5.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Acetyltransf_1 PF00583.25 ORY68056.1 - 2.2e-10 40.8 0.0 4.7e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY68056.1 - 3.4e-09 36.7 0.0 5.7e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY68056.1 - 2e-06 28.1 0.0 3.9e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain NicO PF03824.16 ORY68058.1 - 7.5e-47 160.0 2.1 7.5e-47 160.0 2.1 2.2 2 0 0 2 2 2 2 High-affinity nickel-transport protein COG5 PF10392.9 ORY68059.1 - 0.043 14.0 1.1 0.051 13.7 1.1 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 TBD PF12845.7 ORY68059.1 - 0.093 12.6 0.5 0.21 11.5 0.5 1.7 1 1 0 1 1 1 0 TBD domain Mog1 PF04603.12 ORY68059.1 - 0.11 12.8 0.9 0.14 12.6 0.9 1.3 1 1 0 1 1 1 0 Ran-interacting Mog1 protein APG6_N PF17675.1 ORY68059.1 - 0.51 10.9 7.0 0.66 10.5 7.0 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region KfrA_N PF11740.8 ORY68059.1 - 1.7 9.4 13.0 0.093 13.4 7.9 1.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DivIC PF04977.15 ORY68059.1 - 1.8 8.4 5.3 0.92 9.3 2.2 2.0 1 1 1 2 2 2 0 Septum formation initiator DAO PF01266.24 ORY68060.1 - 1.6e-53 182.5 0.1 2.9e-53 181.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ORY68060.1 - 3.7e-43 146.4 0.0 7.2e-43 145.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase EF-hand_7 PF13499.6 ORY68060.1 - 3.5e-12 46.6 0.1 9.5e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY68060.1 - 1.7e-10 39.6 1.1 3.9e-05 22.9 0.1 3.1 3 0 0 3 3 3 2 EF hand FAD_binding_2 PF00890.24 ORY68060.1 - 2e-10 40.3 0.6 2.5e-05 23.5 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain EF-hand_6 PF13405.6 ORY68060.1 - 6.4e-08 31.9 0.5 0.00068 19.4 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORY68060.1 - 1.4e-07 31.3 0.1 8e-07 28.8 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY68060.1 - 3.7e-07 29.3 3.5 0.013 14.9 0.1 2.7 2 1 1 3 3 3 2 EF hand FAD_oxidored PF12831.7 ORY68060.1 - 1.3e-05 24.7 0.2 0.00015 21.3 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY68060.1 - 0.00096 18.5 0.0 0.0026 17.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY68060.1 - 0.0045 17.5 0.2 0.036 14.6 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY68060.1 - 0.005 17.0 0.3 0.016 15.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORY68060.1 - 0.011 14.8 0.5 0.19 10.8 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORY68060.1 - 0.017 14.4 0.3 0.071 12.3 0.3 1.9 1 1 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY68060.1 - 0.032 13.5 0.0 0.095 11.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY68060.1 - 0.038 12.7 0.3 0.061 12.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 ORY68060.1 - 0.046 13.6 0.1 0.089 12.7 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dockerin_1 PF00404.18 ORY68060.1 - 0.059 13.6 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Dockerin type I domain Thi4 PF01946.17 ORY68060.1 - 0.063 12.5 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 ORY68060.1 - 0.096 13.1 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Rnk_N PF14760.6 ORY68061.1 - 2.5 8.7 6.5 8.5 7.0 0.0 2.7 3 1 0 3 3 3 0 Rnk N-terminus MetJ PF01340.20 ORY68062.1 - 0.0049 16.8 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 Met Apo-repressor, MetJ Na_Ca_ex PF01699.24 ORY68063.1 - 1.8e-10 40.9 3.2 1.9e-10 40.9 3.2 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein Seipin PF06775.14 ORY68064.1 - 2.9e-38 131.9 0.3 5.5e-38 131.1 0.0 1.5 2 0 0 2 2 2 1 Putative adipose-regulatory protein (Seipin) Promethin PF16015.5 ORY68064.1 - 0.44 10.5 8.1 2.9 7.9 2.3 2.3 2 0 0 2 2 2 0 Promethin DUF3328 PF11807.8 ORY68064.1 - 0.86 9.3 1.9 7.2 6.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) Na_Ca_ex PF01699.24 ORY68066.1 - 8.4e-19 68.0 27.6 2.7e-12 46.9 12.1 3.9 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 ORY68066.1 - 1.8e-15 57.4 12.5 1.8e-15 57.4 12.5 4.0 3 0 0 3 3 3 1 Inner membrane component domain OSTMP1 PF09777.9 ORY68066.1 - 0.024 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Nucleo_P87 PF07267.11 ORY68066.1 - 1.7 7.4 3.5 2.7 6.7 3.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MetJ PF01340.20 ORY68067.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Met Apo-repressor, MetJ Birna_RdRp PF04197.12 ORY68069.1 - 0.071 11.4 0.0 0.09 11.1 0.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Hormone_2 PF00123.20 ORY68069.1 - 0.25 11.3 2.4 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 Peptide hormone DUF5592 PF17332.2 ORY68070.1 - 0.029 14.9 0.5 0.074 13.6 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5592) ATP-synt_C PF00137.21 ORY68071.1 - 2.2e-31 108.0 35.0 8.6e-18 64.4 15.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C IncD PF17628.2 ORY68071.1 - 7.9 6.3 8.1 2.2 8.1 4.2 1.8 1 1 1 2 2 2 0 Inclusion membrane protein D Yip1 PF04893.17 ORY68074.1 - 0.0023 17.7 0.3 0.0031 17.3 0.3 1.1 1 0 0 1 1 1 1 Yip1 domain DEAD_2 PF06733.15 ORY68075.1 - 1e-53 181.5 0.0 3e-53 180.1 0.0 1.7 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 ORY68075.1 - 5.4e-46 156.7 0.1 8.5e-40 136.5 0.0 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 ORY68075.1 - 7.4e-43 146.7 0.0 1.5e-42 145.6 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 ORY68075.1 - 6.4e-05 23.0 0.0 0.0059 16.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY68075.1 - 0.00069 19.4 0.0 0.075 12.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY68075.1 - 0.069 13.4 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORY68075.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY68075.1 - 0.12 11.6 0.0 8.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 ORY68075.1 - 0.13 10.9 0.0 13 4.4 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain COesterase PF00135.28 ORY68077.1 - 7.7e-64 216.4 0.0 1.6e-63 215.4 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY68077.1 - 1.2e-05 25.3 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 ORY68077.1 - 0.12 12.0 0.1 1.3 8.6 0.1 2.1 2 0 0 2 2 2 0 Putative esterase Glyco_transf_90 PF05686.12 ORY68078.1 - 1e-10 41.1 4.1 4.8e-08 32.3 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 PX PF00787.24 ORY69122.1 - 7.4e-15 54.9 0.0 7.9e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 PX domain Rotavirus_VP1 PF12289.8 ORY69122.1 - 0.033 13.3 0.0 0.045 12.8 0.0 1.3 1 1 0 1 1 1 0 Rotavirus VP1 C-terminal domain CENP-T_C PF15511.6 ORY69123.1 - 2.5e-07 30.8 0.1 3e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY69123.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY69123.1 - 0.0002 21.7 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY69123.1 - 0.0013 19.1 0.1 0.0015 18.9 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY69123.1 - 0.0014 18.8 0.1 0.0029 17.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY69123.1 - 0.099 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 ORY69124.1 - 1.7e-51 174.0 3.5 1.9e-51 173.8 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY69124.1 - 5.1e-05 23.6 0.1 7.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY69124.1 - 8e-05 22.7 0.1 0.00016 21.8 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY69124.1 - 0.00027 21.6 1.1 0.00032 21.3 1.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY69124.1 - 0.00062 20.0 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY69124.1 - 0.016 15.3 0.3 0.024 14.7 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY69124.1 - 0.059 13.4 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Apc13p PF05839.11 ORY69125.1 - 0.0074 16.4 0.9 0.019 15.1 0.6 1.8 2 0 0 2 2 2 1 Apc13p protein Arginosuc_synth PF00764.19 ORY69126.1 - 1.1e-151 505.6 0.0 1.3e-151 505.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORY69126.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORY69126.1 - 0.041 12.7 0.0 0.06 12.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase FAD_binding_3 PF01494.19 ORY69127.1 - 7.5e-19 68.2 0.2 3.7e-07 29.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 ORY69127.1 - 1.7e-05 24.6 1.3 0.0084 15.7 0.5 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY69127.1 - 0.00015 21.1 0.1 0.00082 18.7 0.1 1.7 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY69127.1 - 0.00032 19.7 0.1 0.011 14.6 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 ORY69127.1 - 0.00042 19.5 0.0 0.0011 18.2 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein SE PF08491.10 ORY69127.1 - 0.00062 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 ORY69127.1 - 0.00084 19.4 0.0 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY69127.1 - 0.0029 17.8 0.3 0.0092 16.2 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY69127.1 - 0.0062 17.1 0.1 0.67 10.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY69127.1 - 0.0076 15.4 0.0 0.23 10.6 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 ORY69127.1 - 0.013 14.6 1.3 0.066 12.3 0.8 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ORY69127.1 - 0.028 13.6 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 ORY69127.1 - 0.048 12.2 0.0 0.25 9.8 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.14 ORY69127.1 - 0.05 12.3 0.1 0.077 11.7 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 ORY69127.1 - 0.061 12.6 0.0 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PI3_PI4_kinase PF00454.27 ORY69128.1 - 1.9e-49 168.8 0.0 4.3e-49 167.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 ORY69128.1 - 2.3e-29 102.5 0.7 1e-28 100.3 0.7 2.3 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 ORY69128.1 - 7.4e-12 44.9 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 ORY69128.1 - 0.051 14.0 2.0 2.5 8.5 0.0 4.6 3 0 0 3 3 3 0 HEAT repeats TPR_14 PF13428.6 ORY69128.1 - 0.054 14.3 1.3 1.2 10.2 0.1 4.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY69128.1 - 1.4 9.8 4.3 8.4 7.3 0.1 4.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ArgJ PF01960.18 ORY69129.1 - 4.8e-149 496.2 0.4 4.8e-149 496.2 0.4 1.3 2 0 0 2 2 2 1 ArgJ family DUF1932 PF09130.11 ORY69130.1 - 3e-17 62.3 0.1 7.4e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.15 ORY69130.1 - 2e-08 34.6 0.1 6e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY69130.1 - 0.00046 20.7 0.1 0.0017 18.9 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Phasin_2 PF09361.10 ORY69130.1 - 0.00098 19.4 2.1 0.0013 18.9 0.4 2.2 2 0 0 2 2 2 1 Phasin protein Rho_N PF07498.12 ORY69130.1 - 0.16 11.9 0.0 0.5 10.4 0.0 1.9 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Ank_5 PF13857.6 ORY69131.1 - 2.8e-13 49.8 0.5 2.5e-07 30.9 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY69131.1 - 9.5e-11 42.0 0.1 3.3e-05 24.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY69131.1 - 4.7e-10 39.9 0.0 7.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY69131.1 - 1e-09 38.4 0.2 2.8e-06 27.5 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY69131.1 - 2.3e-07 30.6 0.0 0.00091 19.5 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Pil1 PF13805.6 ORY69132.1 - 2.5e-44 151.8 2.3 3.9e-44 151.1 2.3 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 UPF0242 PF06785.11 ORY69132.1 - 0.098 12.8 6.9 0.07 13.2 5.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 ORY69132.1 - 0.11 11.0 2.6 0.17 10.4 2.6 1.3 1 0 0 1 1 1 0 Macoilin family DUF2852 PF11014.8 ORY69132.1 - 0.33 11.1 4.3 0.65 10.2 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) CsbD PF05532.12 ORY69133.1 - 0.063 13.2 3.2 0.16 11.9 3.2 1.6 1 0 0 1 1 1 0 CsbD-like DAGK_cat PF00781.24 ORY69134.1 - 7.2e-20 70.9 0.0 1.4e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Mucin PF01456.17 ORY69135.1 - 0.58 10.1 7.2 1.2 9.1 7.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein F-box-like PF12937.7 ORY69136.1 - 0.00059 19.7 1.2 0.0064 16.4 1.2 2.5 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY69136.1 - 0.02 15.3 8.8 1.2 9.7 0.4 5.4 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 ORY69137.1 - 8.8e-11 42.1 0.0 1.3e-05 25.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY69137.1 - 2.1e-10 39.7 0.1 0.00016 21.3 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY69137.1 - 2e-08 33.2 0.0 0.00018 20.8 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 ORY69137.1 - 7.3e-07 29.4 0.0 0.0011 19.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORY69137.1 - 0.0047 16.8 0.0 0.17 11.7 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_11 PF08976.11 ORY69137.1 - 0.22 12.4 0.0 0.31 11.9 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Ribul_P_3_epim PF00834.19 ORY69138.1 - 1.8e-60 203.7 0.1 2.1e-60 203.5 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 ORY69138.1 - 0.044 13.1 0.2 0.058 12.7 0.2 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG CsbD PF05532.12 ORY69139.1 - 0.062 13.2 3.2 0.16 11.9 3.2 1.6 1 0 0 1 1 1 0 CsbD-like 2OG-FeII_Oxy_3 PF13640.6 ORY69140.1 - 1.9e-10 41.5 0.0 2.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily N_formyltrans_C PF18216.1 ORY69140.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Fungal_trans PF04082.18 ORY69141.1 - 1.9e-12 46.8 0.0 2.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY69141.1 - 1.5e-06 28.2 8.0 2.8e-06 27.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 ORY69141.1 - 0.21 11.9 0.8 0.51 10.6 0.8 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain TauD PF02668.16 ORY69142.1 - 2e-56 191.8 1.8 2.4e-56 191.5 1.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LRR_4 PF12799.7 ORY69143.1 - 0.0046 17.3 3.4 0.56 10.7 0.2 4.4 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) DUF4024 PF13216.6 ORY69143.1 - 0.074 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4024) DUF2420 PF10336.9 ORY69145.1 - 1.4e-09 37.9 0.0 1.6e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2420) GHMP_kinases_N PF00288.26 ORY69146.1 - 2e-09 37.5 0.1 4.2e-09 36.5 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY69146.1 - 0.007 16.7 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Cyclin_N PF00134.23 ORY69147.1 - 1.4e-38 131.5 0.0 7.1e-38 129.2 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY69147.1 - 2.4e-09 37.3 0.1 4e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3246 PF11596.8 ORY69147.1 - 0.15 11.4 1.7 0.21 11.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) KH_6 PF15985.5 ORY69148.1 - 2e-14 53.6 0.1 3.8e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 ORY69148.1 - 1.9e-13 49.9 0.1 6.2e-13 48.3 0.1 1.8 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 ORY69148.1 - 0.14 12.8 0.0 1.9 9.1 0.0 2.3 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 DUF5347 PF17282.2 ORY69149.1 - 0.059 13.7 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5347) PEGSRP PF07623.11 ORY69149.1 - 0.14 11.9 3.7 0.18 11.6 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) FAM184 PF15665.5 ORY69149.1 - 0.79 9.5 12.1 65 3.2 12.1 2.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Phasin PF05597.11 ORY69149.1 - 5.8 6.9 13.6 4.6 7.3 3.1 3.2 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SET PF00856.28 ORY69151.1 - 7e-07 29.8 0.0 1.7e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 SET domain RNA_pol_Rpb4 PF03874.16 ORY69152.1 - 2.5e-18 66.6 0.0 4.6e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Vma12 PF11712.8 ORY69153.1 - 5.9e-20 71.7 0.0 8.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase LapA_dom PF06305.11 ORY69153.1 - 0.092 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RNA_pol_Rpc4 PF05132.14 ORY69156.1 - 7.8e-26 91.3 0.0 7.8e-26 91.3 0.0 4.1 4 1 0 4 4 4 1 RNA polymerase III RPC4 TFIID_30kDa PF03540.13 ORY69157.1 - 1.1e-24 86.1 0.1 1.7e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 ORY69157.1 - 0.066 13.2 0.1 7.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Bromodomain associated Ribosomal_L7Ae PF01248.26 ORY69158.1 - 2.9e-20 71.8 0.0 3.5e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PMM PF03332.13 ORY69159.1 - 3.3e-96 321.3 0.0 3.8e-96 321.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 ORY69159.1 - 0.025 14.3 0.0 0.28 10.9 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 ORY69159.1 - 0.22 11.0 0.0 1.1 8.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) PMM PF03332.13 ORY69160.1 - 9.9e-107 355.7 0.9 1.1e-106 355.5 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 ORY69160.1 - 1e-05 25.4 0.1 4.7e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SQHop_cyclase_C PF13243.6 ORY69161.1 - 1e-50 172.6 3.7 3.2e-48 164.5 0.9 2.6 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY69161.1 - 1.9e-49 168.4 0.4 1e-38 133.1 0.0 4.3 3 2 3 6 6 6 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ORY69161.1 - 5e-32 109.3 7.9 1.7e-14 53.2 0.0 6.8 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ORY69161.1 - 8.6e-07 28.3 0.4 0.00016 20.8 0.2 3.0 2 1 1 3 3 3 2 A-macroglobulin TED domain Pec_lyase PF09492.10 ORY69161.1 - 0.006 15.9 0.8 0.061 12.6 0.0 2.9 2 1 2 4 4 4 1 Pectic acid lyase Actin PF00022.19 ORY69162.1 - 1.4e-11 43.6 0.0 2.2e-10 39.8 0.0 2.4 3 0 0 3 3 3 1 Actin FeoB_Cyto PF17910.1 ORY69162.1 - 0.037 14.6 0.0 0.07 13.7 0.0 1.4 1 0 0 1 1 1 0 FeoB cytosolic helical domain zf-UBP PF02148.19 ORY69163.1 - 1.8e-19 69.8 3.9 4.3e-19 68.6 3.9 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein BRAP2 PF07576.12 ORY69163.1 - 1.5e-17 63.6 0.0 2.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-RING_2 PF13639.6 ORY69163.1 - 1.8e-07 31.4 9.2 1.8e-07 31.4 9.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY69163.1 - 0.00014 21.6 8.0 0.00014 21.6 8.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY69163.1 - 0.0017 18.1 7.6 0.0017 18.1 7.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY69163.1 - 0.0024 17.9 4.6 0.0024 17.9 4.6 2.4 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY69163.1 - 0.0087 15.9 6.3 0.0087 15.9 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY69163.1 - 0.52 10.1 5.2 1.2 9.0 5.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 ORY69163.1 - 0.57 10.3 6.5 1.1 9.3 6.5 1.5 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 ORY69163.1 - 0.58 10.5 16.3 0.044 14.1 9.2 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Lar_restr_allev PF14354.6 ORY69163.1 - 3.5 8.1 10.2 0.59 10.5 2.5 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ANAPC11 PF12861.7 ORY69163.1 - 4.1 7.5 11.0 0.047 13.7 3.2 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger SRF-TF PF00319.18 ORY69164.1 - 1e-19 69.7 0.2 1.5e-19 69.2 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) TFIIF_alpha PF05793.12 ORY69164.1 - 0.21 10.1 5.1 0.36 9.4 5.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cation_efflux PF01545.21 ORY69165.1 - 3.4e-49 167.3 2.9 3.4e-49 167.3 2.9 2.5 3 1 0 3 3 3 1 Cation efflux family V_ATPase_I PF01496.19 ORY69165.1 - 0.21 9.5 0.0 0.27 9.1 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SQHop_cyclase_C PF13243.6 ORY69166.1 - 6.1e-51 173.4 0.3 5.1e-48 163.8 0.1 2.3 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY69166.1 - 2.5e-48 164.7 1.8 7.8e-40 136.8 0.3 4.1 3 1 0 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ORY69166.1 - 3.6e-27 93.8 3.6 1.1e-09 37.9 0.2 5.8 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ORY69166.1 - 0.00015 20.9 0.0 0.0009 18.3 0.0 2.2 2 0 0 2 2 2 1 A-macroglobulin TED domain Pec_lyase PF09492.10 ORY69166.1 - 0.0035 16.7 0.0 8 5.7 0.0 4.4 3 1 2 5 5 5 1 Pectic acid lyase Mago-bind PF09282.10 ORY69166.1 - 0.014 15.2 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 Mago binding Glutaredoxin PF00462.24 ORY69169.1 - 2.3e-14 53.4 0.0 3.4e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin TPR_2 PF07719.17 ORY69170.1 - 4.8e-20 70.0 1.5 0.00074 19.5 0.1 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY69170.1 - 7.1e-20 69.9 1.8 0.0018 18.0 0.2 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY69170.1 - 3.9e-15 55.3 1.7 3.1e-06 26.8 0.3 4.7 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.6 ORY69170.1 - 6.5e-15 55.5 0.3 6.6e-08 33.1 0.0 2.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY69170.1 - 7.4e-13 47.6 5.3 0.0041 17.2 0.5 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY69170.1 - 1.2e-12 48.0 4.5 2.1e-05 24.7 0.1 4.3 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY69170.1 - 6.2e-10 39.4 7.2 6e-07 29.9 0.2 3.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY69170.1 - 6.4e-10 39.0 1.7 0.022 15.5 0.0 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY69170.1 - 4.2e-08 32.7 0.1 1 9.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY69170.1 - 0.00045 20.4 1.3 2.8 8.5 0.0 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY69170.1 - 0.00055 20.0 0.1 0.38 10.9 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY69170.1 - 0.00085 19.1 9.5 0.3 11.0 0.1 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 ORY69170.1 - 0.0053 15.7 0.9 0.061 12.2 0.1 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 HemY_N PF07219.13 ORY69170.1 - 0.0095 16.1 0.1 0.0095 16.1 0.1 2.6 2 1 1 3 3 3 1 HemY protein N-terminus ANAPC3 PF12895.7 ORY69170.1 - 0.013 15.7 0.1 1 9.6 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY69170.1 - 0.014 16.0 7.3 1.6 9.6 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 ORY69170.1 - 0.023 14.4 2.6 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 ORY69170.1 - 0.028 13.6 0.4 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY69170.1 - 0.059 13.7 1.4 0.11 12.8 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 ORY69170.1 - 0.19 11.8 6.0 0.75 9.9 0.6 3.3 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 ORY69170.1 - 0.25 12.1 9.9 13 6.6 0.1 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 ORY69170.1 - 0.29 11.5 1.6 8.9 6.8 0.0 2.8 3 0 0 3 3 2 0 PPR repeat DUF4398 PF14346.6 ORY69170.1 - 4 8.1 14.7 2.7 8.7 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) zf-DNL PF05180.12 ORY69171.1 - 7.9e-26 89.8 0.0 1.2e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 DNL zinc finger TRAUB PF08164.12 ORY69172.1 - 5.8e-28 97.2 0.7 2.5e-27 95.2 0.0 2.4 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 ORY69172.1 - 1.8e-24 87.0 0.0 1.8e-24 87.0 0.0 2.9 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor eIF-3c_N PF05470.12 ORY69172.1 - 0.16 10.3 12.1 0.33 9.2 12.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 ORY69172.1 - 0.56 8.4 14.4 1.1 7.5 14.4 1.4 1 0 0 1 1 1 0 CDC45-like protein SURF2 PF05477.11 ORY69172.1 - 2.3 7.9 16.8 0.85 9.3 13.8 1.9 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 ORY69172.1 - 3.4 7.0 30.6 0.75 9.2 25.7 2.1 2 0 0 2 2 2 0 SDA1 CENP-R PF06729.12 ORY69173.1 - 0.052 13.5 2.5 0.084 12.8 2.5 1.3 1 0 0 1 1 1 0 Kinetochore component, CENP-R Draxin PF15550.6 ORY69173.1 - 0.33 10.8 2.9 0.45 10.3 2.9 1.1 1 0 0 1 1 1 0 Draxin DUF1289 PF06945.13 ORY69174.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) SKN1 PF03935.15 ORY69175.1 - 4.2e-170 566.4 7.2 5.3e-170 566.1 7.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF3185 PF11381.8 ORY69175.1 - 0.076 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Orn_Arg_deC_N PF02784.16 ORY69176.1 - 5.5e-73 245.4 0.0 7.1e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORY69176.1 - 5.5e-16 58.6 0.0 7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Med5 PF08689.10 ORY69177.1 - 1.2e-25 89.6 0.0 1.8e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit Med5 PC_rep PF01851.22 ORY69178.1 - 2.5e-44 147.5 19.1 6.6e-08 32.6 0.0 8.7 8 0 0 8 8 8 7 Proteasome/cyclosome repeat RPN2_C PF18004.1 ORY69178.1 - 1.1e-40 139.2 8.4 2.9e-39 134.6 7.2 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 ORY69178.1 - 1.1e-19 70.5 3.6 2.7e-15 56.5 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 ORY69178.1 - 2.2e-05 24.3 1.0 4.8 7.7 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 ORY69178.1 - 0.011 16.3 7.3 0.055 14.0 0.1 4.5 4 1 2 6 6 6 0 HEAT-like repeat HEAT_PBS PF03130.16 ORY69178.1 - 0.053 14.2 1.5 21 6.2 0.1 4.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat MetRS-N PF09635.10 ORY69178.1 - 0.11 13.0 0.0 3 8.4 0.0 2.5 2 0 0 2 2 2 0 MetRS-N binding domain Cpn60_TCP1 PF00118.24 ORY69264.1 - 1.7e-40 139.1 0.0 2.1e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF356 PF04009.12 ORY69264.1 - 0.097 13.0 0.1 0.16 12.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF356) Mito_carr PF00153.27 ORY69265.1 - 2.3e-57 190.9 5.9 6.8e-23 80.4 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DAGAT PF03982.13 ORY69268.1 - 3.7e-98 328.1 0.0 4.4e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF1502 PF07397.11 ORY69269.1 - 0.021 14.6 1.3 0.46 10.4 0.0 2.8 3 0 0 3 3 3 0 Repeat of unknown function (DUF1502) TPT PF03151.16 ORY69271.1 - 9.9e-20 71.1 22.0 1.3e-19 70.7 22.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Ras PF00071.22 ORY69273.1 - 2e-51 173.8 0.0 2.4e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY69273.1 - 1.2e-19 70.7 0.0 1.6e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY69273.1 - 2.2e-07 30.5 0.0 3e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY69273.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 ORY69273.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DLIC PF05783.11 ORY69273.1 - 0.04 12.8 0.0 1 8.1 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Gtr1_RagA PF04670.12 ORY69273.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY69273.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Cyclophil_like2 PF18050.1 ORY69273.1 - 0.21 11.5 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin-like family PduV-EutP PF10662.9 ORY69273.1 - 0.25 11.1 0.0 0.49 10.1 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SelK_SelG PF10961.8 ORY69274.1 - 1.2e-07 32.2 3.0 2.2e-07 31.4 3.0 1.4 1 1 0 1 1 1 1 Selenoprotein SelK_SelG RhlB PF12300.8 ORY69274.1 - 0.62 10.2 7.4 0.88 9.7 7.4 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Stealth_CR2 PF11380.8 ORY69275.1 - 4.1e-15 55.9 0.0 2e-12 47.2 0.0 2.7 3 0 0 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 ORY69275.1 - 1.1e-10 41.3 0.2 3.7e-10 39.6 0.1 2.0 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 Stealth_CR4 PF17103.5 ORY69275.1 - 2e-06 27.6 0.0 4.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 ORY69275.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 ELFV_dehydrog PF00208.21 ORY69276.1 - 5.9e-74 248.8 1.9 7.4e-74 248.5 1.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 ORY69276.1 - 4.5e-51 172.1 0.0 7.9e-51 171.3 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF3431 PF11913.8 ORY69277.1 - 1.5e-10 41.2 0.0 1.6e-09 37.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) Exo_endo_phos PF03372.23 ORY69278.1 - 8.5e-16 58.2 0.0 3e-15 56.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ETC_C1_NDUFA5 PF04716.14 ORY69279.1 - 4.4e-24 84.1 0.0 7.2e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region ApbA PF02558.16 ORY69280.1 - 1.8e-30 105.6 0.0 2.6e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ORY69280.1 - 1.3e-23 83.6 0.0 5.3e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal MTCP1 PF08991.10 ORY69281.1 - 6.2e-23 80.8 8.8 7.2e-23 80.6 8.8 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Peptidase_M28 PF04389.17 ORY69282.1 - 3.4e-34 118.3 0.0 5.6e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY69282.1 - 0.0024 17.6 0.0 0.0082 15.9 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 HTH_IclR PF09339.10 ORY69282.1 - 0.049 13.4 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 IclR helix-turn-helix domain RhoGEF PF00621.20 ORY69283.1 - 4e-29 102.2 0.0 7.6e-26 91.5 0.0 2.4 2 0 0 2 2 2 2 RhoGEF domain BAR PF03114.18 ORY69283.1 - 3.4e-06 26.9 0.0 1.5e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 BAR domain SpoIIE PF07228.12 ORY69284.1 - 2.8e-11 43.7 0.0 2.4e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ORY69284.1 - 1.7e-09 37.6 0.0 3.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 ORY69284.1 - 4.3e-07 29.8 0.0 0.00021 21.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Sporozoite_P67 PF05642.11 ORY69284.1 - 1.2 7.1 14.7 2 6.4 14.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Acyltransferase PF01553.21 ORY69285.1 - 2e-22 79.3 0.0 2.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Meth_synt_2 PF01717.18 ORY69286.1 - 1.2e-22 80.6 0.0 2e-22 79.9 0.0 1.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY69286.1 - 0.0039 16.8 0.1 0.057 12.9 0.0 2.1 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain SIS PF01380.22 ORY69287.1 - 8.3e-14 51.6 0.1 1.1e-12 47.9 0.0 2.7 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.6 ORY69287.1 - 0.14 12.2 0.1 6.1 6.9 0.1 2.3 1 1 0 1 1 1 0 SIS domain TPK_catalytic PF04263.16 ORY69288.1 - 1.2e-36 125.4 0.0 1.6e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 ORY69288.1 - 4.4e-13 48.8 0.0 6.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Adeno_E3_CR2 PF02439.15 ORY69289.1 - 0.056 13.2 0.4 0.096 12.5 0.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Amnionless PF14828.6 ORY69289.1 - 0.16 10.8 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless Abhydrolase_6 PF12697.7 ORY69290.1 - 1e-06 29.5 2.6 1e-06 29.5 2.6 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY69290.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Aldolase_II PF00596.21 ORY69291.1 - 4.7e-42 144.0 0.0 5.9e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Rit1_C PF17184.4 ORY69292.1 - 2.1e-93 312.7 0.0 2.6e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 ORY69292.1 - 3.9e-20 72.2 0.0 8e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain Gly_transf_sug PF04488.15 ORY69293.1 - 2.8e-21 76.0 0.0 4.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY69293.1 - 0.024 13.9 1.3 1.3 8.3 0.2 2.7 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.16 ORY69294.1 - 1.6e-48 165.5 57.8 8.7e-48 163.0 33.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY69294.1 - 4.6e-06 25.8 24.4 1.9e-05 23.7 24.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter FPN1 PF06963.12 ORY69294.1 - 0.075 11.6 4.9 0.018 13.6 1.1 2.0 2 1 0 2 2 2 0 Ferroportin1 (FPN1) Presenilin PF01080.17 ORY69295.1 - 0.012 14.5 8.5 0.015 14.1 8.5 1.1 1 0 0 1 1 1 0 Presenilin Pkinase_Tyr PF07714.17 ORY69295.1 - 0.025 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Ndc1_Nup PF09531.10 ORY69295.1 - 0.037 12.7 11.7 0.041 12.6 11.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TP53IP5 PF15331.6 ORY69295.1 - 0.13 12.4 5.1 0.19 11.9 5.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SOG2 PF10428.9 ORY69295.1 - 0.14 11.4 18.0 0.18 11.0 18.0 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein FSA_C PF10479.9 ORY69295.1 - 0.45 8.6 15.1 0.59 8.2 15.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Peptidase_S64 PF08192.11 ORY69295.1 - 0.83 8.1 9.0 0.91 7.9 9.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 SR-25 PF10500.9 ORY69295.1 - 1.4 8.5 20.2 2.7 7.6 20.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.7 ORY69295.1 - 2.4 6.2 12.4 2.9 5.9 12.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.12 ORY69295.1 - 4.2 5.9 16.0 5.2 5.6 16.0 1.1 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 ORY69295.1 - 5.1 5.8 12.5 6 5.6 12.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 ORY69295.1 - 5.1 4.1 10.9 6 3.8 10.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Raftlin PF15250.6 ORY69295.1 - 6.1 5.5 9.3 7.6 5.2 9.3 1.1 1 0 0 1 1 1 0 Raftlin SPX PF03105.19 ORY69295.1 - 7.2 6.4 18.0 9 6.1 18.0 1.1 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 ORY69296.1 - 2.4e-57 194.3 0.0 3.2e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY69296.1 - 1.7e-24 86.5 0.0 2.8e-24 85.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY69296.1 - 0.0018 17.7 0.2 1 8.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 ORY69296.1 - 0.0027 17.1 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY69296.1 - 0.0062 15.4 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY69296.1 - 0.014 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 ORY69297.1 - 4.9e-21 74.6 7.3 0.003 18.4 0.3 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY69297.1 - 7.1e-13 48.7 0.1 7.7e-08 32.5 0.1 4.5 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY69297.1 - 0.0021 18.0 0.1 0.035 14.0 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY69297.1 - 0.014 14.1 0.0 0.025 13.2 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY69297.1 - 0.045 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain PD40 PF07676.12 ORY69297.1 - 0.12 12.4 0.5 34 4.6 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Thioredoxin PF00085.20 ORY69298.1 - 0.0028 17.6 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 ORY69298.1 - 0.03 13.3 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Phosducin Acetyltransf_1 PF00583.25 ORY69300.1 - 0.00017 21.8 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY69300.1 - 0.002 18.1 0.0 0.0061 16.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY69300.1 - 0.006 17.0 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HMG_box PF00505.19 ORY69302.1 - 9.9e-12 45.1 1.1 3.5e-11 43.4 1.1 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY69302.1 - 6.1e-07 29.9 0.7 1.9e-06 28.3 0.7 2.0 1 0 0 1 1 1 1 HMG-box domain Drc1-Sld2 PF11719.8 ORY69302.1 - 0.16 11.5 24.0 0.38 10.3 24.2 1.4 1 1 0 1 1 1 0 DNA replication and checkpoint protein DUF3438 PF11920.8 ORY69302.1 - 1.5 8.0 5.2 3 7.0 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) NOA36 PF06524.12 ORY69302.1 - 4.3 6.6 15.5 0.16 11.3 9.5 1.7 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 ORY69302.1 - 6.9 4.6 20.8 12 3.9 20.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Glyco_hydro_47 PF01532.20 ORY69303.1 - 5e-144 480.6 0.0 9.6e-144 479.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_2 PF07719.17 ORY69304.1 - 2.8e-07 30.1 3.9 0.0045 17.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY69304.1 - 3.9e-06 26.9 0.3 1.1e-05 25.5 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY69304.1 - 5.1e-06 26.1 2.4 0.00075 19.2 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY69304.1 - 5.6e-06 26.8 4.9 8e-06 26.3 1.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY69304.1 - 0.00037 21.1 2.8 0.21 12.5 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY69304.1 - 0.0011 18.9 0.7 0.042 13.9 0.1 2.4 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 ORY69304.1 - 0.005 17.0 0.4 0.015 15.6 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORY69304.1 - 0.0098 16.0 3.4 0.23 11.7 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY69304.1 - 0.013 15.1 0.2 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.6 ORY69304.1 - 0.03 15.0 3.4 23 5.8 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY69304.1 - 0.034 14.4 3.9 1.2 9.5 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY69304.1 - 0.16 12.1 0.1 4.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat O-FucT PF10250.9 ORY69305.1 - 0.00034 20.4 0.0 0.0055 16.4 0.0 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase zf-C2H2 PF00096.26 ORY69306.1 - 1e-11 44.6 3.6 4.8e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY69306.1 - 2.8e-06 27.7 2.7 0.033 15.0 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY69306.1 - 0.0012 19.2 9.5 0.0018 18.6 1.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_aberr PF17017.5 ORY69306.1 - 0.1 12.7 0.1 15 5.7 0.0 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 ORY69306.1 - 0.13 12.0 0.1 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type Tri3 PF07428.11 ORY69307.1 - 0.00085 18.3 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 O-FucT PF10250.9 ORY69308.1 - 3.4e-05 23.7 0.1 0.014 15.1 0.1 3.1 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase UPF0242 PF06785.11 ORY69309.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_transf_90 PF05686.12 ORY69310.1 - 7.8e-30 104.1 0.0 1.7e-29 102.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_hydro_20 PF00728.22 ORY69311.1 - 3.9e-88 296.2 0.0 4.7e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY69311.1 - 2.7e-15 57.2 0.0 6.5e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY69311.1 - 3.9e-05 24.4 0.0 0.00018 22.3 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Kri1 PF05178.12 ORY69312.1 - 4e-27 94.8 6.8 4e-27 94.8 6.8 7.4 6 2 1 7 7 7 2 KRI1-like family Kri1_C PF12936.7 ORY69312.1 - 1.2e-25 89.5 0.5 1.2e-25 89.5 0.5 5.2 7 0 0 7 7 7 1 KRI1-like family C-terminal CTK3 PF12243.8 ORY69313.1 - 3.4e-33 114.3 0.0 5.1e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 ORY69313.1 - 3.9e-16 59.0 5.4 1.2e-15 57.4 0.1 3.2 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus CAP_N PF01213.19 ORY69313.1 - 0.0075 15.8 7.3 0.0075 15.8 7.3 3.5 2 1 1 3 3 3 1 Adenylate cyclase associated (CAP) N terminal P_C PF06640.11 ORY69313.1 - 0.079 13.1 9.8 0.16 12.1 9.8 1.5 1 0 0 1 1 1 0 P protein C-terminus NDUFB11 PF17250.2 ORY69313.1 - 0.11 13.2 0.3 0.36 11.5 0.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit SOG2 PF10428.9 ORY69313.1 - 2.4 7.2 9.8 4 6.5 9.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Polysacc_lyase PF14099.6 ORY69314.1 - 0.026 14.4 0.0 0.067 13.0 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide lyase Polysacc_lyase PF14099.6 ORY69315.1 - 0.014 15.3 0.0 0.029 14.2 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide lyase DRIM PF07539.12 ORY69316.1 - 7.7e-177 589.4 10.2 9.2e-176 585.8 0.0 4.9 4 2 0 5 5 5 1 Down-regulated in metastasis CLASP_N PF12348.8 ORY69316.1 - 0.046 13.3 0.1 4 6.9 0.0 2.9 1 1 0 2 2 2 0 CLASP N terminal MMS19_N PF14500.6 ORY69316.1 - 0.065 12.8 5.5 0.083 12.5 1.4 3.2 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF4042 PF13251.6 ORY69316.1 - 0.095 12.4 0.9 14 5.3 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) 4HBT_2 PF13279.6 ORY69317.1 - 7.3e-13 49.1 0.0 1.1e-12 48.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ORY69317.1 - 1.3e-05 25.5 0.0 3e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 ORY69317.1 - 0.00012 21.5 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase Aminotran_1_2 PF00155.21 ORY69318.1 - 1e-17 64.4 0.0 2e-17 63.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II zf-rbx1 PF12678.7 ORY69320.1 - 9.9e-25 86.6 14.0 1.3e-24 86.2 14.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY69320.1 - 9.5e-18 64.1 10.6 1.2e-17 63.7 10.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 ORY69320.1 - 4.1e-06 27.0 15.8 0.00017 21.9 15.8 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY69320.1 - 0.0038 17.0 15.6 0.29 11.0 15.6 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY69320.1 - 0.0061 16.4 13.8 0.12 12.3 13.8 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY69320.1 - 0.084 12.7 11.6 1.2 9.1 6.0 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY69320.1 - 0.19 11.5 15.7 20 5.0 15.7 2.5 1 1 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 ORY69320.1 - 0.36 10.5 16.7 0.093 12.4 6.6 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORY69320.1 - 0.99 9.6 10.6 3.3 8.0 10.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 ORY69320.1 - 1 9.5 9.2 3.7 7.6 9.2 2.0 1 1 0 1 1 1 0 RING-type zinc-finger SCIFF PF13165.6 ORY69320.1 - 1.4 8.9 8.1 2.6 8.1 8.1 1.6 1 1 0 1 1 1 0 Six-cysteine peptide SCIFF zf-C3HC4_4 PF15227.6 ORY69320.1 - 7.7 6.8 10.4 0.33 11.2 0.8 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Peptidase_S24 PF00717.23 ORY69321.1 - 2.1e-10 40.4 0.1 6.1e-10 38.9 0.0 1.8 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 ORY69321.1 - 0.0032 17.3 0.0 0.45 10.3 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 PAP_RNA-bind PF04926.15 ORY69322.1 - 2.3e-51 173.8 0.0 3.2e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain PAP_central PF04928.17 ORY69322.1 - 7.8e-34 116.8 0.2 1.1e-33 116.3 0.2 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain Zds_C PF08632.10 ORY69405.1 - 1.1e-22 79.4 0.6 2e-22 78.7 0.6 1.3 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2076 PF09849.9 ORY69405.1 - 0.0003 20.9 0.6 0.0003 20.9 0.6 4.0 3 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2076) Methyltransf_25 PF13649.6 ORY69406.1 - 0.00057 20.5 0.7 0.19 12.4 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY69406.1 - 0.00058 20.4 0.4 0.014 16.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY69406.1 - 0.0028 17.5 0.0 0.018 14.9 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY69406.1 - 0.0054 16.5 0.2 4.3 7.1 0.3 2.4 2 0 0 2 2 2 2 Methyltransferase domain SAP PF02037.27 ORY69407.1 - 0.071 12.9 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 SAP domain Myb_DNA-binding PF00249.31 ORY69409.1 - 0.00096 19.3 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY69409.1 - 0.009 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ilar_coat PF01787.16 ORY69409.1 - 0.018 14.8 1.5 0.031 14.1 1.5 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein Rrn6 PF10214.9 ORY69409.1 - 0.36 9.3 5.8 0.47 8.9 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RabGAP-TBC PF00566.18 ORY69410.1 - 5.8e-53 179.7 0.0 1.5e-52 178.4 0.0 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Nucleopor_Nup85 PF07575.13 ORY69411.1 - 4.9e-83 279.6 0.0 1.2e-46 159.4 0.0 2.2 2 0 0 2 2 2 2 Nup85 Nucleoporin ETC_C1_NDUFA5 PF04716.14 ORY69411.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 ETC complex I subunit conserved region Ndc1_Nup PF09531.10 ORY69412.1 - 1.6 7.3 5.2 1.6 7.3 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SPX PF03105.19 ORY69413.1 - 8.1e-40 137.9 3.3 1.8e-28 100.6 0.7 2.7 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 ORY69413.1 - 3e-25 89.2 32.4 4.6e-25 88.6 32.4 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 ORY69413.1 - 3.8e-24 85.4 35.8 3.8e-24 85.4 35.8 1.6 1 1 1 2 2 2 2 Citrate transporter TFIIA_gamma_N PF02268.16 ORY69413.1 - 0.0099 15.9 0.1 0.083 12.9 0.0 2.3 2 0 0 2 2 2 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF5090 PF17009.5 ORY69413.1 - 1.7 8.6 5.1 0.5 10.3 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) CD34_antigen PF06365.12 ORY69416.1 - 0.005 16.4 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family TMEM154 PF15102.6 ORY69416.1 - 0.0094 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Smr PF01713.21 ORY69417.1 - 6.2e-07 29.7 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 ORY69417.1 - 0.0013 19.0 4.6 0.0013 19.0 4.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) DMA PF03474.14 ORY69417.1 - 0.041 13.5 0.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 DMRTA motif MFS_1 PF07690.16 ORY69418.1 - 1.5e-23 83.3 43.0 1.5e-23 83.3 43.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily ArAE_2_N PF10337.9 ORY69419.1 - 1.7e-54 185.7 8.2 1.9e-48 165.7 2.0 3.1 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 ORY69419.1 - 1.4e-36 126.5 0.0 3.5e-36 125.2 0.0 1.6 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY69419.1 - 2.4e-15 56.8 17.9 2.4e-15 56.8 17.9 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein-like FUSC PF04632.12 ORY69419.1 - 1.6e-05 23.7 6.2 1.6e-05 23.7 6.2 3.9 4 0 0 4 4 4 2 Fusaric acid resistance protein family ArAE_1 PF06081.11 ORY69419.1 - 2.5 8.3 7.9 34 4.6 7.9 2.8 1 1 0 1 1 1 0 Aromatic acid exporter family member 1 Clat_adaptor_s PF01217.20 ORY69422.1 - 3.7e-55 185.8 2.2 4.1e-55 185.6 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_M3 PF01432.20 ORY69423.1 - 4e-132 441.7 0.2 6e-132 441.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 ORY69423.1 - 0.086 12.5 0.2 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Peptidase M50B-like FCH PF00611.23 ORY69424.1 - 9.3e-12 45.1 0.1 3e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 ORY69424.1 - 4.4e-10 39.0 0.1 8.2e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY69424.1 - 1.5e-09 37.6 0.1 3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY69424.1 - 7.4e-07 28.8 0.0 1.6e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FAD_binding_3 PF01494.19 ORY69425.1 - 2.2e-11 43.6 0.0 3.2e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 ORY69425.1 - 0.0043 16.1 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Squalene epoxidase Myb_DNA-bind_6 PF13921.6 ORY69426.1 - 2.3e-06 27.7 0.9 0.0066 16.7 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF4685 PF15737.5 ORY69426.1 - 0.0088 16.5 0.8 0.02 15.3 0.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4685) Myb_DNA-binding PF00249.31 ORY69426.1 - 0.023 14.9 1.9 0.29 11.4 0.9 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Fib_alpha PF08702.10 ORY69426.1 - 0.36 11.0 2.4 1.7 8.8 1.3 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Prok-TraM PF09228.10 ORY69426.1 - 0.57 10.6 3.9 3.7 8.0 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM DUF4473 PF14747.6 ORY69426.1 - 0.75 10.4 5.5 19 5.9 0.6 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4473) GAS PF13851.6 ORY69426.1 - 0.82 9.0 10.1 0.62 9.4 4.5 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Tli4_N PF18443.1 ORY69426.1 - 1.1 9.7 3.6 4.7 7.6 0.8 2.4 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain Striatin PF08232.12 ORY69426.1 - 2.2 8.9 20.6 5.4 7.6 5.0 3.0 1 1 1 2 2 2 0 Striatin family DUF4472 PF14739.6 ORY69426.1 - 5.6 7.7 11.7 2.7 8.8 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) DUF4407 PF14362.6 ORY69426.1 - 6.4 6.0 14.7 2.2 7.6 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) adh_short PF00106.25 ORY69427.1 - 2.2e-28 99.0 0.0 3.2e-28 98.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY69427.1 - 1.2e-21 77.4 0.0 1.4e-21 77.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY69427.1 - 4.3e-11 43.0 0.0 5.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY69427.1 - 0.00026 20.9 0.1 0.00032 20.6 0.1 1.3 1 1 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 ORY69427.1 - 0.0075 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 ORY69427.1 - 0.073 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SH3_1 PF00018.28 ORY69428.1 - 2.3e-16 59.1 0.1 4.1e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY69428.1 - 6.2e-12 45.2 0.2 1.1e-11 44.4 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY69428.1 - 2.8e-11 42.9 0.1 4.5e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 ORY69428.1 - 1.5e-05 25.2 0.6 3.7e-05 23.9 0.6 1.7 1 0 0 1 1 1 1 GAT domain Hrs_helical PF12210.8 ORY69428.1 - 0.00067 20.2 0.4 0.00067 20.2 0.4 2.2 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate VHS PF00790.19 ORY69428.1 - 0.028 14.3 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 VHS domain Vps4_C PF09336.10 ORY69428.1 - 0.05 13.6 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain DASH_Spc34 PF08657.10 ORY69428.1 - 2.8 7.7 8.8 71 3.1 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Spc34 F-box-like PF12937.7 ORY69429.1 - 0.0018 18.1 2.1 0.004 17.0 2.1 1.6 1 0 0 1 1 1 1 F-box-like Trp_syntA PF00290.20 ORY69431.1 - 7.6e-82 274.0 0.2 1.2e-81 273.4 0.2 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 ORY69431.1 - 4.5e-47 160.9 0.2 1.1e-46 159.6 0.2 1.6 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.6 ORY69431.1 - 0.034 13.8 0.1 0.091 12.4 0.1 1.7 1 1 0 1 1 1 0 Periplasmic binding protein PA PF02225.22 ORY69431.1 - 0.11 12.5 0.0 0.38 10.8 0.0 1.9 1 0 0 1 1 1 0 PA domain UQ_con PF00179.26 ORY69432.1 - 4.7e-16 58.7 0.0 4.7e-16 58.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY69432.1 - 0.081 13.2 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain zf-C2HC5 PF06221.13 ORY69433.1 - 1.1e-13 50.9 7.8 1.7e-13 50.4 7.8 1.2 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF3886 PF13025.6 ORY69433.1 - 1.1 9.5 5.6 1.9 8.7 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Tenui_PVC2 PF06656.11 ORY69434.1 - 0.22 9.4 0.1 0.27 9.1 0.1 1.1 1 0 0 1 1 1 0 Tenuivirus PVC2 protein MFS_1 PF07690.16 ORY69435.1 - 3.6e-19 68.9 45.1 3.6e-19 68.9 45.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S15 PF02129.18 ORY69435.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CENP-H PF05837.12 ORY69438.1 - 0.036 14.5 2.3 0.036 14.5 2.3 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TMCO5 PF14992.6 ORY69438.1 - 0.076 12.6 4.4 0.092 12.3 4.4 1.1 1 0 0 1 1 1 0 TMCO5 family MFS_1 PF07690.16 ORY69439.1 - 5.3e-16 58.5 46.8 5.3e-16 58.5 46.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2760 PF10816.8 ORY69439.1 - 0.034 14.0 0.1 0.057 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) RhoGAP PF00620.27 ORY69440.1 - 1.1e-45 155.2 0.0 1.8e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 ORY69440.1 - 6e-12 45.7 0.0 1.9e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1708 PF08101.11 ORY69440.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Nup54 PF13874.6 ORY69440.1 - 8.1 6.5 6.3 3.6 7.7 2.1 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 Glyco_transf_8 PF01501.20 ORY69442.1 - 5.5e-39 134.3 0.0 6.8e-36 124.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 8 Glyco_transf_64 PF09258.10 ORY69442.1 - 7.2e-35 120.4 0.1 2.9e-34 118.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_24 PF18404.1 ORY69442.1 - 8.5e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Glyco_tranf_2_3 PF13641.6 ORY69442.1 - 0.0062 16.5 0.1 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Exostosin PF03016.15 ORY69443.1 - 4.6e-20 72.0 0.0 1.1e-19 70.8 0.0 1.7 1 1 0 1 1 1 1 Exostosin family MFS_1 PF07690.16 ORY69444.1 - 1.1e-43 149.6 55.2 1.1e-43 149.6 55.2 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY69444.1 - 2.3e-12 46.2 21.7 3e-12 45.8 21.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BTB PF00651.31 ORY69445.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Ysc84 PF04366.12 ORY69446.1 - 7.5e-45 151.8 0.6 1.4e-44 150.9 0.6 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator Peptidase_M75 PF09375.10 ORY69448.1 - 0.015 14.8 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Imelysin dsrm PF00035.26 ORY69449.1 - 9.9e-05 23.0 0.0 0.00017 22.3 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 ORY69449.1 - 0.086 13.0 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Dicer dimerisation domain Peptidase_A22B PF04258.13 ORY69450.1 - 0.0023 17.5 1.1 0.38 10.2 0.0 2.7 3 0 0 3 3 3 2 Signal peptide peptidase ABC2_membrane_5 PF13346.6 ORY69450.1 - 0.9 9.1 4.3 1.6 8.2 1.0 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF1348 PF07080.11 ORY69451.1 - 1.5e-56 189.9 5.2 1.8e-56 189.6 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 ORY69451.1 - 0.084 13.5 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain HECT PF00632.25 ORY69452.1 - 6.9e-72 242.5 0.0 9.7e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 ORY69452.1 - 0.019 15.0 1.8 0.12 12.4 0.0 3.4 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat TFIIA PF03153.13 ORY69452.1 - 2.9 7.8 39.0 7.7 6.4 0.8 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BTB PF00651.31 ORY69453.1 - 0.031 14.5 0.0 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain KCT2 PF17818.1 ORY69453.1 - 0.16 12.1 0.8 0.3 11.2 0.8 1.4 1 0 0 1 1 1 0 Keratinocyte-associated gene product CENP-B_dimeris PF09026.10 ORY69453.1 - 1.3 9.5 6.5 2.5 8.5 6.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MFS_1 PF07690.16 ORY69454.1 - 2.4e-43 148.4 54.0 2.4e-43 148.4 54.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY69454.1 - 3.3e-11 42.3 25.3 5.3e-11 41.6 25.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Exostosin PF03016.15 ORY69455.1 - 7.2e-19 68.1 0.0 1.4e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 Exostosin family Pmp3 PF01679.17 ORY69456.1 - 6e-26 90.4 8.5 6.6e-26 90.3 8.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ubiquitin PF00240.23 ORY70598.1 - 2.6e-25 88.0 0.3 3.5e-25 87.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY70598.1 - 9.6e-14 51.0 0.2 1.2e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY70598.1 - 0.0005 20.5 0.2 0.0015 18.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY70598.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY70598.1 - 0.014 15.4 0.4 0.079 13.0 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 ORY70598.1 - 0.063 13.9 0.0 0.073 13.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY70598.1 - 0.094 12.8 0.1 0.24 11.5 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Cellulase PF00150.18 ORY70599.1 - 6.7e-25 88.1 0.8 9.1e-25 87.6 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SpoIIIAH PF12685.7 ORY70599.1 - 0.0025 17.7 2.2 0.0036 17.2 2.2 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF1180 PF06679.12 ORY70599.1 - 4.9 7.6 8.2 7.5 6.9 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Mitoc_mL59 PF18126.1 ORY70600.1 - 5.6e-25 88.1 1.7 7.4e-25 87.7 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 CorA PF01544.18 ORY70601.1 - 3.4e-21 75.8 0.1 5.5e-09 35.8 0.1 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Gp58 PF07902.11 ORY70601.1 - 3.4 5.8 5.5 5 5.3 5.5 1.1 1 0 0 1 1 1 0 gp58-like protein Macoilin PF09726.9 ORY70601.1 - 10 4.6 10.5 16 3.9 10.5 1.2 1 0 0 1 1 1 0 Macoilin family Rep_fac-A_3 PF08661.11 ORY70602.1 - 8.6e-28 96.8 0.1 9.6e-28 96.6 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Glucodextran_B PF09136.10 ORY70602.1 - 0.063 13.7 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain B Myosin_N PF02736.19 ORY70602.1 - 0.082 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain LRR_1 PF00560.33 ORY70603.1 - 3.4 8.6 5.7 9.2 7.3 0.1 3.6 3 1 0 3 3 3 0 Leucine Rich Repeat Aminotran_5 PF00266.19 ORY70604.1 - 4.1e-12 45.7 0.0 8.7e-12 44.7 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Abhydrolase_3 PF07859.13 ORY70605.1 - 9.9e-26 90.9 0.0 1.1e-22 80.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY70605.1 - 2.8e-19 69.2 0.0 1.3e-15 57.1 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase DUF2974 PF11187.8 ORY70605.1 - 0.0024 17.4 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORY70605.1 - 0.013 16.1 0.5 0.013 16.1 0.5 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY70605.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORY70606.1 - 6.8e-19 68.6 0.0 2.3e-15 57.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY70606.1 - 2.3e-15 56.3 0.0 5.6e-11 41.9 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORY70606.1 - 0.028 13.9 0.1 0.11 12.0 0.0 1.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF2974 PF11187.8 ORY70606.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Spc7 PF08317.11 ORY70607.1 - 0.0069 15.3 9.5 0.011 14.6 9.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein TRAF_BIRC3_bd PF16673.5 ORY70607.1 - 0.015 15.1 4.1 0.015 15.1 4.1 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Atg14 PF10186.9 ORY70607.1 - 0.13 11.3 6.8 0.23 10.5 6.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GrpE PF01025.19 ORY70607.1 - 0.24 11.0 3.7 0.48 10.1 3.7 1.4 1 0 0 1 1 1 0 GrpE Fez1 PF06818.15 ORY70607.1 - 3.4 8.1 11.8 6.4 7.2 11.8 1.4 1 0 0 1 1 1 0 Fez1 Exonuc_VII_L PF02601.15 ORY70607.1 - 8.8 5.8 8.6 14 5.2 8.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_membrane PF00664.23 ORY70608.1 - 1.4e-54 185.6 36.7 8.8e-32 110.8 16.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY70608.1 - 1.6e-50 171.2 0.0 1.9e-27 96.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY70608.1 - 7.7e-10 38.6 0.4 0.0006 19.3 0.0 3.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY70608.1 - 2.1e-05 24.6 0.5 0.15 12.1 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY70608.1 - 2.9e-05 24.6 1.2 0.035 14.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY70608.1 - 0.00018 21.5 0.1 0.067 13.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY70608.1 - 0.0002 21.8 4.1 0.11 12.9 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORY70608.1 - 0.0003 20.5 2.6 0.092 12.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 ORY70608.1 - 0.0037 17.0 0.2 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_21 PF13304.6 ORY70608.1 - 0.0057 16.5 1.4 3.2 7.5 0.1 2.8 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY70608.1 - 0.0077 15.8 0.3 1.3 8.5 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_15 PF13175.6 ORY70608.1 - 0.0091 15.7 0.0 4.5 6.9 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 ORY70608.1 - 0.011 15.5 0.3 7.9 6.2 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 ORY70608.1 - 0.014 14.7 0.3 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 ORY70608.1 - 0.016 15.4 0.2 4 7.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 ORY70608.1 - 0.017 15.7 0.3 1.5 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY70608.1 - 0.036 13.6 0.1 0.87 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY70608.1 - 0.045 13.7 0.1 1.5 8.9 0.0 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORY70608.1 - 0.071 13.0 0.9 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 ORY70608.1 - 0.086 13.2 0.0 8.6 6.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.23 ORY70608.1 - 0.09 12.8 2.1 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.6 ORY70608.1 - 0.11 12.2 2.7 1.2 8.8 0.0 3.0 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 ORY70608.1 - 0.14 11.7 0.9 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ORY70608.1 - 0.15 12.5 0.8 19 5.7 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 ORY70608.1 - 0.17 11.7 0.0 0.43 10.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 ORY70608.1 - 0.57 9.0 2.6 2.5 6.9 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 ORY70608.1 - 0.9 9.8 3.2 8 6.7 0.1 2.7 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 ORY70608.1 - 1.8 8.6 3.3 3.7 7.6 0.8 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain zf-C2H2_aberr PF17017.5 ORY70609.1 - 4.7e-05 23.6 0.2 0.38 10.9 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY70609.1 - 0.011 16.2 1.2 0.79 10.3 0.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY70609.1 - 0.011 16.5 3.5 1.6 9.8 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY70609.1 - 0.03 14.8 3.4 0.17 12.4 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Med3 PF11593.8 ORY70609.1 - 0.91 8.6 11.4 1.5 7.9 11.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.32 ORY70610.1 - 6.1e-29 99.7 8.2 7e-06 26.7 0.1 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY70610.1 - 1.6e-08 34.8 0.0 0.39 11.0 0.0 4.3 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY70610.1 - 0.057 11.9 0.0 2.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain NIF PF03031.18 ORY70612.1 - 9.2e-12 45.0 0.0 9.5e-11 41.7 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase NIF PF03031.18 ORY70613.1 - 0.00061 19.6 0.0 0.0018 18.0 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Mpv17_PMP22 PF04117.12 ORY70614.1 - 2e-23 82.4 0.1 3.7e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Actin PF00022.19 ORY70615.1 - 1.2e-28 99.8 0.0 1.3e-13 50.3 0.0 3.2 3 0 0 3 3 3 3 Actin Actin_micro PF17003.5 ORY70615.1 - 5.6e-11 42.2 0.0 4.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 ORY70615.1 - 0.0043 15.9 0.1 0.029 13.2 0.0 2.2 3 0 0 3 3 3 1 MreB/Mbl protein ubiquitin PF00240.23 ORY70616.1 - 1.6e-19 69.4 0.0 4.4e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 ORY70616.1 - 9.3e-10 38.2 0.0 1.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CDC48_2 PF02933.17 ORY70616.1 - 0.041 13.7 0.2 0.65 9.8 0.1 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Lectin_like PF18560.1 ORY70616.1 - 0.052 13.7 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Lectin like domain PHF5 PF03660.14 ORY70618.1 - 7e-52 174.0 11.0 7.9e-52 173.8 11.0 1.0 1 0 0 1 1 1 1 PHF5-like protein Tnp_zf-ribbon_2 PF13842.6 ORY70618.1 - 0.15 12.9 0.9 0.15 12.9 0.9 3.5 4 0 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon PolC_DP2 PF03833.13 ORY70618.1 - 0.68 7.7 7.0 0.71 7.7 7.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 ORY70618.1 - 2.4 8.2 15.1 2.6 8.2 1.5 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-C6H2 PF15801.5 ORY70618.1 - 4.9 7.5 9.8 0.69 10.3 1.5 2.9 2 1 1 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Cys_Met_Meta_PP PF01053.20 ORY70619.1 - 2.1e-125 418.2 0.0 2.9e-125 417.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.26 ORY70619.1 - 1.3e-14 54.2 0.6 4.6e-14 52.4 0.6 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain Met_gamma_lyase PF06838.11 ORY70619.1 - 0.0012 17.5 0.0 0.004 15.7 0.0 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase GHMP_kinases_C PF08544.13 ORY70619.1 - 0.0014 19.0 3.2 0.0024 18.2 0.1 2.8 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 ORY70619.1 - 0.0017 17.9 0.1 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.21 ORY70619.1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY70619.1 - 0.0083 15.4 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Fasciclin PF02469.22 ORY70621.1 - 5.7e-08 33.0 0.1 7.8e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF5017 PF16409.5 ORY70621.1 - 0.028 13.9 4.4 0.83 9.1 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5017) NAD_binding_6 PF08030.12 ORY70622.1 - 5.3e-19 68.9 0.0 7.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY70622.1 - 6.6e-19 68.3 8.3 2.1e-18 66.7 8.3 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY70622.1 - 5.3e-08 32.9 0.1 0.00032 20.7 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain 3-HAO PF06052.12 ORY70624.1 - 2.5e-52 176.5 0.0 5e-51 172.3 0.0 2.0 1 1 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 ORY70624.1 - 2e-05 24.2 0.1 0.1 12.3 0.0 2.3 1 1 0 2 2 2 2 Cupin domain Cupin_1 PF00190.22 ORY70624.1 - 0.0057 16.3 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Cupin zf-tcix PF14952.6 ORY70624.1 - 0.039 13.6 0.0 0.099 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding AraC_binding PF02311.19 ORY70624.1 - 0.19 11.6 0.1 0.83 9.6 0.1 1.9 1 1 1 2 2 2 0 AraC-like ligand binding domain Apolipoprotein PF01442.18 ORY70625.1 - 0.00068 19.6 6.3 0.00068 19.6 6.3 2.2 1 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 ORY70625.1 - 0.0013 18.8 10.5 0.0048 16.9 7.1 2.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 ORY70625.1 - 0.0054 17.0 2.9 2.3 8.5 0.2 2.9 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 ORY70625.1 - 0.012 15.0 8.6 0.19 11.0 3.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Lant_dehydr_C PF14028.6 ORY70625.1 - 0.21 11.1 6.2 0.17 11.4 2.4 2.0 1 1 1 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term BORCS6 PF10157.9 ORY70625.1 - 0.55 10.4 6.8 2 8.6 6.9 2.0 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 6 CENP-H PF05837.12 ORY70625.1 - 0.72 10.3 14.0 3.1 8.3 4.6 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) SprA-related PF12118.8 ORY70625.1 - 1.2 8.2 7.9 1.6 7.8 7.9 1.1 1 0 0 1 1 1 0 SprA-related family WXG100 PF06013.12 ORY70625.1 - 2.7 8.3 7.9 1.9 8.8 0.7 3.9 1 1 3 4 4 4 0 Proteins of 100 residues with WXG DUF4404 PF14357.6 ORY70625.1 - 6.3 7.5 13.9 0.76 10.5 1.7 3.5 3 2 0 3 3 3 0 Domain of unknown function (DUF4404) Syntaxin-6_N PF09177.11 ORY70625.1 - 9.4 6.9 12.1 2.1e+02 2.5 10.5 3.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DEAD PF00270.29 ORY70627.1 - 1.6e-49 168.0 0.0 2.9e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY70627.1 - 1.3e-23 83.5 0.1 1.1e-22 80.4 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY70627.1 - 7.3e-19 67.8 0.1 1.5e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY70627.1 - 9.8e-08 32.2 0.0 3.6e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RED_N PF07808.13 ORY70628.1 - 2.3e-16 60.1 9.7 2.3e-16 60.1 9.7 2.5 2 1 0 2 2 2 1 RED-like protein N-terminal region Rnk_N PF14760.6 ORY70628.1 - 0.0089 16.5 1.9 0.032 14.7 1.9 2.0 1 0 0 1 1 1 1 Rnk N-terminus Ribosomal_L26 PF16906.5 ORY70628.1 - 0.063 13.8 2.6 0.15 12.5 2.6 1.6 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Tropomyosin_1 PF12718.7 ORY70629.1 - 7.7e-45 152.6 24.4 9.5e-45 152.3 24.4 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 ORY70629.1 - 2.6e-10 40.1 26.3 3.7e-05 23.2 5.8 3.0 1 1 2 3 3 3 3 Tropomyosin GAS PF13851.6 ORY70629.1 - 1.8e-05 24.2 21.9 0.00028 20.3 6.5 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 ORY70629.1 - 0.0074 16.3 12.7 0.02 14.9 2.5 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) DUF724 PF05266.14 ORY70629.1 - 0.0088 15.9 21.7 0.15 11.8 7.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF724) DHR10 PF18595.1 ORY70629.1 - 0.011 15.8 24.1 0.13 12.3 7.5 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 ORY70629.1 - 0.015 15.4 24.6 0.68 10.0 5.5 3.0 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 ORY70629.1 - 0.015 15.3 23.7 0.26 11.3 10.9 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CLZ PF16526.5 ORY70629.1 - 0.015 15.6 19.2 1.7 9.0 5.4 3.7 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HrpB7 PF09486.10 ORY70629.1 - 0.018 15.5 19.0 0.13 12.7 5.3 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Csm1_N PF18504.1 ORY70629.1 - 0.018 15.4 5.1 0.018 15.4 5.1 3.6 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF3450 PF11932.8 ORY70629.1 - 0.021 14.2 20.0 0.28 10.4 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.8 ORY70629.1 - 0.024 14.7 20.5 0.54 10.3 7.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 ORY70629.1 - 0.025 14.8 19.1 0.77 10.1 0.4 4.1 1 1 2 4 4 4 0 ABC transporter C-terminal domain ATG16 PF08614.11 ORY70629.1 - 0.025 14.8 25.8 0.089 13.0 11.6 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 ORY70629.1 - 0.027 14.5 23.3 0.52 10.4 9.3 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase KELK PF15796.5 ORY70629.1 - 0.032 14.7 21.5 0.033 14.6 1.8 3.5 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase APG6_N PF17675.1 ORY70629.1 - 0.04 14.4 30.0 0.12 12.9 16.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4164 PF13747.6 ORY70629.1 - 0.046 14.0 24.1 0.54 10.6 7.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 ORY70629.1 - 0.048 13.8 21.5 4 7.6 6.1 4.3 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Sec2p PF06428.11 ORY70629.1 - 0.049 13.6 20.1 1.2 9.1 3.1 3.1 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Tup_N PF08581.10 ORY70629.1 - 0.051 13.9 1.2 0.051 13.9 1.2 3.2 1 1 0 3 3 3 0 Tup N-terminal UPF0242 PF06785.11 ORY70629.1 - 0.053 13.6 21.7 0.13 12.3 10.2 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4094 PF13334.6 ORY70629.1 - 0.055 13.9 2.3 0.055 13.9 2.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) Cluap1 PF10234.9 ORY70629.1 - 0.062 12.7 19.4 0.046 13.1 6.1 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 Fez1 PF06818.15 ORY70629.1 - 0.063 13.7 21.1 0.27 11.7 20.2 2.0 1 1 0 1 1 1 0 Fez1 Spc7 PF08317.11 ORY70629.1 - 0.09 11.6 24.0 0.65 8.8 10.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein HalX PF08663.10 ORY70629.1 - 0.14 12.5 24.2 1.5 9.2 0.5 4.4 3 1 1 4 4 4 0 HalX domain EzrA PF06160.12 ORY70629.1 - 0.14 10.3 17.2 0.031 12.5 7.0 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Lectin_N PF03954.14 ORY70629.1 - 0.18 11.6 12.4 0.59 9.9 6.7 2.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Med2 PF11214.8 ORY70629.1 - 0.2 11.8 11.8 1.5 9.0 3.4 2.5 1 1 1 2 2 2 0 Mediator complex subunit 2 DUF919 PF06034.11 ORY70629.1 - 0.21 11.4 6.0 0.21 11.5 1.3 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) CHDCT2 PF08074.11 ORY70629.1 - 0.21 11.7 10.2 0.56 10.4 4.1 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Rab5-bind PF09311.11 ORY70629.1 - 0.22 10.9 20.8 0.13 11.6 9.7 2.1 1 1 1 2 2 2 0 Rabaptin-like protein HOOK PF05622.12 ORY70629.1 - 0.22 9.6 21.4 0.64 8.1 21.5 1.7 1 1 0 1 1 1 0 HOOK protein TRAF_BIRC3_bd PF16673.5 ORY70629.1 - 0.24 11.2 10.9 0.6 9.9 1.9 3.2 3 2 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain HAUS-augmin3 PF14932.6 ORY70629.1 - 0.26 10.8 19.7 0.015 14.9 11.6 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 DUF4407 PF14362.6 ORY70629.1 - 0.28 10.5 18.5 0.58 9.5 18.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 ORY70629.1 - 0.37 11.1 19.8 1.7 9.0 11.0 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 ORY70629.1 - 0.75 9.9 27.9 8.4 6.5 7.6 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 ORY70629.1 - 0.8 10.4 17.0 3.7 8.3 0.8 3.9 2 2 1 3 3 3 0 SlyX Laminin_II PF06009.12 ORY70629.1 - 0.83 9.7 17.1 1.2 9.2 3.4 2.3 1 1 1 2 2 2 0 Laminin Domain II KLRAQ PF10205.9 ORY70629.1 - 0.92 9.8 17.2 0.16 12.2 5.9 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 ORY70629.1 - 0.94 9.7 19.0 1.6 9.0 10.5 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding CTNNBL PF08216.11 ORY70629.1 - 0.98 9.6 10.3 0.077 13.2 3.9 2.3 1 1 2 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Mt_ATP-synt_D PF05873.12 ORY70629.1 - 1.1 9.1 11.5 0.18 11.6 4.5 2.0 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Ax_dynein_light PF10211.9 ORY70629.1 - 1.1 9.1 20.2 1.9 8.4 8.7 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain Seryl_tRNA_N PF02403.22 ORY70629.1 - 1.3 9.3 22.0 0.85 9.9 13.9 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.19 ORY70629.1 - 1.3 8.8 26.8 1.8 8.3 12.8 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Fib_alpha PF08702.10 ORY70629.1 - 1.5 9.0 11.8 3.3 7.9 9.2 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family WXG100 PF06013.12 ORY70629.1 - 1.6 9.0 11.1 2.4 8.5 0.7 3.2 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Jnk-SapK_ap_N PF09744.9 ORY70629.1 - 1.6 8.9 24.5 3.1 8.0 15.9 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 ORY70629.1 - 1.6 7.7 18.1 34 3.4 18.1 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 ORY70629.1 - 2.1 8.8 24.0 2.2 8.7 4.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) FAM76 PF16046.5 ORY70629.1 - 2.4 7.5 16.8 24 4.2 16.8 1.9 1 1 0 1 1 1 0 FAM76 protein Sugarporin_N PF11471.8 ORY70629.1 - 2.5 8.1 15.9 4.5 7.3 0.7 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension FlaC_arch PF05377.11 ORY70629.1 - 3.8 8.0 16.4 8.4 6.9 1.2 4.1 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) CCDC-167 PF15188.6 ORY70629.1 - 4.4 7.7 17.1 0.41 11.0 8.4 2.9 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 DUF641 PF04859.12 ORY70629.1 - 4.4 7.6 15.2 0.47 10.8 2.1 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF948 PF06103.11 ORY70629.1 - 6 7.2 8.9 13 6.1 1.9 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Swi5 PF07061.11 ORY70629.1 - 7.9 6.6 19.7 6.5 6.9 0.8 4.0 1 1 3 4 4 4 0 Swi5 Fzo_mitofusin PF04799.13 ORY70629.1 - 7.9 6.0 12.3 1.3 8.6 2.3 2.6 1 1 3 4 4 4 0 fzo-like conserved region DUF1690 PF07956.11 ORY70629.1 - 8.6 6.8 23.0 2.6 8.5 9.0 2.8 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Nsp1_C PF05064.13 ORY70629.1 - 8.7 6.2 15.5 1.4 8.7 2.1 3.1 1 1 0 2 2 2 0 Nsp1-like C-terminal region T3SSipB PF16535.5 ORY70629.1 - 9 6.7 17.7 4.7 7.7 3.7 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB Med21 PF11221.8 ORY70629.1 - 9.1 6.5 16.7 27 5.0 15.6 2.0 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Thioredoxin_8 PF13905.6 ORY70630.1 - 9.4e-07 29.1 0.0 2.5e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 ORY70630.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.21 ORY70630.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Pyocin_S PF06958.12 ORY70630.1 - 2.8 8.5 7.2 0.52 10.9 0.1 2.3 2 0 0 2 2 2 0 S-type Pyocin TPR_11 PF13414.6 ORY70631.1 - 5.6e-09 35.5 0.5 0.037 13.7 0.2 4.4 5 0 0 5 5 5 2 TPR repeat TPR_14 PF13428.6 ORY70631.1 - 2.2e-07 31.1 19.4 0.0073 17.0 2.7 5.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY70631.1 - 3.3e-07 30.8 20.4 0.0021 18.7 5.1 5.3 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY70631.1 - 1.3e-05 25.0 0.1 0.056 13.7 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY70631.1 - 1.4e-05 24.8 8.9 0.18 12.0 0.2 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY70631.1 - 2.5e-05 24.7 6.2 0.0054 17.2 0.9 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY70631.1 - 0.0018 18.1 12.0 0.7 9.8 1.1 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY70631.1 - 0.0034 17.9 0.7 0.0034 17.9 0.7 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY70631.1 - 0.0036 17.6 13.4 0.0092 16.3 4.0 3.7 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY70631.1 - 0.012 15.4 2.9 5.6 7.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY70631.1 - 0.53 10.4 9.2 4.5 7.5 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_A22B PF04258.13 ORY70632.1 - 0.0047 16.5 0.9 0.016 14.8 0.1 2.1 2 1 0 2 2 2 1 Signal peptide peptidase DUF3165 PF11364.8 ORY70632.1 - 6.7 7.1 6.4 31 5.0 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) DUF936 PF06075.12 ORY70634.1 - 0.0042 16.1 7.1 0.0061 15.6 7.1 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) FAM220 PF15487.6 ORY70634.1 - 7.2 6.2 11.8 12 5.4 11.8 1.4 1 0 0 1 1 1 0 FAM220 family Pkinase PF00069.25 ORY70635.1 - 2e-73 247.0 0.0 2.2e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY70635.1 - 6.1e-30 104.4 0.0 9.7e-30 103.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY70635.1 - 0.0042 16.4 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Steroid_dh PF02544.16 ORY70636.1 - 8.7e-35 119.9 0.7 1.2e-34 119.4 0.7 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.23 ORY70636.1 - 1.2e-06 28.1 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 ORY70636.1 - 0.0013 19.4 0.1 0.002 18.8 0.1 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF1295 PF06966.12 ORY70636.1 - 0.0017 17.9 0.6 0.0024 17.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ubiquitin_2 PF14560.6 ORY70636.1 - 0.0087 16.5 0.1 0.02 15.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY70636.1 - 0.062 13.3 5.2 1.8 8.7 0.0 3.2 3 1 1 4 4 4 0 Ubiquitin-like domain UN_NPL4 PF11543.8 ORY70636.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 NADH-u_ox-rdase PF10785.9 ORY70637.1 - 8.6e-31 106.5 0.1 1.2e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 ORY70637.1 - 1e-16 60.7 0.0 1.4e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit SIR2 PF02146.17 ORY70638.1 - 1.2e-58 197.9 0.0 1.7e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 ORY70638.1 - 5.5e-07 29.5 1.2 5.7e-06 26.2 0.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 ORY70638.1 - 0.00078 19.2 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain CutC PF03932.14 ORY70638.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 CutC family Methyltransf_28 PF02636.17 ORY70639.1 - 1.2e-36 126.7 0.0 1.9e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase AA_permease_2 PF13520.6 ORY70640.1 - 1e-61 209.1 44.7 1.4e-61 208.6 44.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY70640.1 - 7.4e-18 64.4 37.0 9.8e-18 64.0 37.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4395 PF14340.6 ORY70640.1 - 0.017 15.4 6.4 0.017 15.4 6.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4395) ATP_synth_reg PF14960.6 ORY70640.1 - 0.11 12.0 0.9 0.44 10.1 0.9 2.0 1 0 0 1 1 1 0 ATP synthase regulation BSP_II PF05432.11 ORY70641.1 - 0.03 14.0 6.7 0.43 10.2 2.5 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PTPRCAP PF15713.5 ORY70641.1 - 0.056 13.7 8.5 2.2 8.5 4.7 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PBP1_TM PF14812.6 ORY70641.1 - 0.5 10.8 6.7 0.39 11.1 1.6 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.9 ORY70641.1 - 2.3 6.4 13.7 4.1 5.5 13.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NOA36 PF06524.12 ORY70641.1 - 4.2 6.6 6.0 4.3 6.6 1.2 2.1 2 0 0 2 2 2 0 NOA36 protein CENP-B_dimeris PF09026.10 ORY70641.1 - 6.2 7.3 15.9 4.9 7.6 6.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 ORY70641.1 - 7.2 6.3 11.1 7.1 6.3 4.4 2.4 2 0 0 2 2 2 0 FAM176 family 4HBT_2 PF13279.6 ORY70642.1 - 0.024 15.1 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily TIP_N PF12457.8 ORY70643.1 - 0.0021 18.4 0.6 0.041 14.3 0.1 2.2 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal DUF2183 PF09949.9 ORY70644.1 - 8.7e-29 99.8 0.0 2e-28 98.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 ORY70644.1 - 0.027 13.9 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) PQ-loop PF04193.14 ORY70645.1 - 9.2e-26 89.4 9.2 1.8e-13 50.1 1.4 2.5 2 0 0 2 2 2 2 PQ loop repeat PQ-loop PF04193.14 ORY70646.1 - 1.5e-30 104.8 5.1 1.1e-17 63.5 0.4 3.1 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 ORY70646.1 - 0.026 14.5 0.3 0.026 14.5 0.3 2.5 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange MARVEL PF01284.23 ORY70646.1 - 0.3 11.1 19.7 1.3 9.0 8.3 2.8 1 1 1 2 2 2 0 Membrane-associating domain Acyl-CoA_dh_1 PF00441.24 ORY70647.1 - 4.4e-32 111.4 0.3 6.4e-32 110.8 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY70647.1 - 2.4e-18 66.0 0.0 5.3e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY70647.1 - 1.8e-13 50.5 0.3 3.1e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY70647.1 - 6.5e-12 46.1 0.0 1.8e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY70647.1 - 1.9e-07 31.4 0.0 3.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CoaE PF01121.20 ORY70647.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase Chromo_shadow PF01393.19 ORY70648.1 - 4.7e-11 42.6 0.0 4.9e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.24 ORY70648.1 - 2.2e-08 33.8 1.1 9e-08 31.9 1.1 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2681 PF10883.8 ORY70648.1 - 1.4 9.4 5.9 4.3 7.8 5.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) MCM_bind PF09739.9 ORY70648.1 - 1.9 6.9 9.6 2.6 6.4 9.6 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Peroxin-3 PF04882.12 ORY70648.1 - 3.7 6.4 9.8 5 6.0 9.8 1.3 1 0 0 1 1 1 0 Peroxin-3 Hid1 PF12722.7 ORY70648.1 - 8.4 4.4 10.5 11 4.0 10.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MgsA_C PF12002.8 ORY70649.1 - 1.3e-56 191.2 0.1 2.1e-56 190.5 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 ORY70649.1 - 2e-23 82.5 0.1 4.6e-23 81.4 0.1 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 ORY70649.1 - 3e-15 56.8 0.0 5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY70649.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY70649.1 - 2.4e-08 34.1 0.0 6.6e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY70649.1 - 2.8e-07 31.1 2.4 0.0039 17.6 0.1 2.9 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 ORY70649.1 - 3.1e-06 27.0 0.1 0.016 14.9 0.0 2.3 1 1 1 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ORY70649.1 - 5.5e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 ORY70649.1 - 1.9e-05 24.7 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY70649.1 - 5.5e-05 22.6 0.0 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ORY70649.1 - 0.00019 21.7 1.2 0.0049 17.1 0.4 2.8 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 ORY70649.1 - 0.00023 20.5 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 ORY70649.1 - 0.00035 19.8 0.0 0.00052 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 ORY70649.1 - 0.00049 20.2 0.0 0.0013 18.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Parvo_NS1 PF01057.17 ORY70649.1 - 0.0012 18.0 0.0 0.0037 16.4 0.0 1.6 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 ORY70649.1 - 0.0015 18.3 0.1 0.0034 17.1 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 ORY70649.1 - 0.0025 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY70649.1 - 0.0026 17.5 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY70649.1 - 0.0083 16.7 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY70649.1 - 0.013 15.5 0.3 0.34 10.8 0.1 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ORY70649.1 - 0.015 15.6 0.9 1 9.6 0.2 2.3 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 ORY70649.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 ORY70649.1 - 0.032 14.6 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 ORY70649.1 - 0.033 13.4 0.0 0.087 12.0 0.0 1.6 1 1 1 2 2 2 0 NB-ARC domain AAA_11 PF13086.6 ORY70649.1 - 0.034 13.9 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY70649.1 - 0.048 13.2 1.2 0.094 12.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY70649.1 - 0.054 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY70649.1 - 0.059 13.6 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY70649.1 - 0.062 12.8 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 ORY70649.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 ORY70649.1 - 0.096 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ORY70649.1 - 0.11 11.9 0.1 11 5.4 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein DNA_pol3_delta2 PF13177.6 ORY70649.1 - 0.12 12.1 0.0 2.3 8.0 0.2 2.1 1 1 1 2 2 2 0 DNA polymerase III, delta subunit Secretin_N PF03958.17 ORY70649.1 - 0.5 10.8 0.0 0.5 10.8 0.0 2.7 3 0 0 3 3 1 0 Bacterial type II/III secretion system short domain Histone PF00125.24 ORY70650.1 - 5.7e-42 143.2 0.1 6.2e-42 143.1 0.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY70650.1 - 4.7e-06 26.7 0.0 6.1e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ORY70650.1 - 0.0008 19.6 0.0 0.0011 19.2 0.0 1.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ORY70650.1 - 0.00095 19.5 0.0 0.0013 19.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 ORY70650.1 - 0.021 14.8 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF746 PF05344.11 ORY70650.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) TPR_16 PF13432.6 ORY70651.1 - 4.3e-07 30.5 16.6 0.00097 19.7 3.3 4.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY70651.1 - 5.7e-07 29.2 2.8 2.1 8.7 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY70651.1 - 1.3e-06 28.7 18.7 0.0039 17.9 2.0 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY70651.1 - 2.2e-06 27.2 0.0 0.038 13.7 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_10 PF13374.6 ORY70651.1 - 2.9e-05 23.8 13.0 0.73 9.8 0.7 4.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY70651.1 - 8.2e-05 23.0 5.6 0.0067 16.9 0.8 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY70651.1 - 0.0027 17.8 0.1 3.8 7.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY70651.1 - 0.0034 17.9 0.7 0.0034 17.9 0.7 4.6 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY70651.1 - 0.0071 16.6 13.9 0.45 10.9 3.9 4.2 1 1 4 5 5 5 5 Tetratricopeptide repeat Trypan_PARP PF05887.11 ORY70651.1 - 0.03 14.3 1.0 0.095 12.7 0.2 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TPR_7 PF13176.6 ORY70651.1 - 0.11 12.5 8.1 27 5.1 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY70651.1 - 0.38 11.1 2.4 2.3 8.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY70651.1 - 6.3 7.7 7.1 34 5.3 0.4 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ZZ PF00569.17 ORY70652.1 - 2.1e-20 72.3 55.1 2.2e-07 30.6 4.1 6.2 6 0 0 6 6 6 5 Zinc finger, ZZ type C1_2 PF03107.16 ORY70652.1 - 7.7e-05 22.9 43.9 0.012 16.0 2.6 5.8 5 0 0 5 5 5 4 C1 domain SHNi-TPR PF10516.9 ORY70653.1 - 1.1e-11 44.0 0.0 3.6e-10 39.1 0.0 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 ORY70653.1 - 8.1e-08 32.5 2.6 0.00018 21.7 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY70653.1 - 0.011 15.8 2.9 8.2 6.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4235 PF14019.6 ORY70653.1 - 0.022 14.8 1.0 0.066 13.3 1.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) Bacillus_HBL PF05791.11 ORY70653.1 - 0.064 13.1 1.8 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Laminin_II PF06009.12 ORY70653.1 - 0.13 12.3 7.2 0.084 12.9 3.6 2.4 2 1 0 2 2 2 0 Laminin Domain II MIT PF04212.18 ORY70653.1 - 0.14 12.2 5.6 7.3 6.7 0.0 3.9 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain SKA1 PF07160.12 ORY70653.1 - 1.6 8.5 6.7 1.2 8.9 4.9 1.7 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 ORY70653.1 - 8.3 6.5 6.6 17 5.4 1.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) zf-TFIIIC PF12660.7 ORY70654.1 - 7.4e-19 67.6 1.1 1.4e-18 66.7 1.1 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 ORY70654.1 - 2.5e-18 66.6 0.0 6.6e-18 65.3 0.0 1.7 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term GFO_IDH_MocA PF01408.22 ORY70655.1 - 6.7e-23 81.8 0.2 1.3e-22 80.9 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY70655.1 - 2.2e-10 40.6 0.0 4.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 ORY70655.1 - 0.011 16.3 0.2 0.033 14.8 0.2 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain UCH PF00443.29 ORY70656.1 - 1.3e-74 251.0 0.0 1.6e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ORY70656.1 - 8.2e-18 64.8 0.0 1.8e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 ORY70656.1 - 3.6e-12 46.5 0.0 5.7e-05 22.9 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 ORY70656.1 - 0.0051 16.5 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-FPG_IleRS PF06827.14 ORY70656.1 - 0.018 14.9 1.3 0.97 9.4 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Aminotran_5 PF00266.19 ORY70657.1 - 1.2e-31 110.0 0.0 1.6e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORY70657.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GTP_EFTU PF00009.27 ORY70754.1 - 7.1e-46 156.2 0.0 1.1e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 ORY70754.1 - 4.6e-34 117.6 1.5 4.6e-34 117.6 1.5 1.6 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 ORY70754.1 - 1.1e-24 86.5 0.0 2.6e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY70754.1 - 4.3e-21 74.8 0.0 8.8e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY70754.1 - 1.2e-10 41.6 0.1 2.6e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY70754.1 - 1.8e-06 28.0 0.2 3.3e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 ORY70754.1 - 2.4e-06 27.6 0.0 6.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Roc PF08477.13 ORY70754.1 - 0.019 15.1 0.0 0.074 13.3 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY70754.1 - 0.049 13.1 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 ORY70754.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Aconitase PF00330.20 ORY70755.1 - 2.3e-149 498.3 0.0 2.9e-149 498.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY70755.1 - 4.5e-35 120.8 0.0 7.5e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain SPX PF03105.19 ORY70756.1 - 7.3 6.4 9.6 8.5 6.2 9.6 1.1 1 0 0 1 1 1 0 SPX domain F-box-like PF12937.7 ORY70758.1 - 7.8e-08 32.1 0.6 2.1e-07 30.7 0.6 1.8 1 0 0 1 1 1 1 F-box-like Chs7 PF12271.8 ORY70759.1 - 2.7e-118 394.5 20.6 3.1e-118 394.3 20.6 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone FixQ PF05545.11 ORY70759.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.6 5 0 0 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ DUF2070 PF09843.9 ORY70759.1 - 4.1 5.6 19.2 6.1 5.0 19.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) tRNA-synt_1c PF00749.21 ORY70761.1 - 3.1e-88 295.7 0.0 4.2e-88 295.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain AAR2 PF05282.11 ORY70762.1 - 4.1e-75 253.4 0.2 4.7e-75 253.2 0.2 1.0 1 0 0 1 1 1 1 AAR2 protein F-box-like PF12937.7 ORY70763.1 - 0.082 12.8 0.0 0.54 10.2 0.0 2.4 1 1 0 1 1 1 0 F-box-like LRR_4 PF12799.7 ORY70763.1 - 0.1 13.0 2.6 39 4.9 0.0 4.8 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF4754 PF15946.5 ORY70763.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) hNIFK_binding PF12196.8 ORY70763.1 - 0.54 9.8 2.2 1.1 8.8 2.2 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Pro_dh PF01619.18 ORY70764.1 - 8.5e-55 186.4 0.0 1.5e-54 185.6 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase AAA_18 PF13238.6 ORY70764.1 - 0.19 12.3 0.0 0.36 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 ORY70765.1 - 1.8e-109 365.4 0.3 2.7e-109 364.8 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY70765.1 - 2.7e-05 24.2 0.0 6.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY70765.1 - 0.00014 21.8 0.6 0.0088 16.0 0.6 3.0 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY70765.1 - 0.00051 19.6 0.1 0.01 15.4 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY70765.1 - 0.00065 19.8 3.4 0.8 9.7 0.0 3.2 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.13 ORY70765.1 - 0.016 14.3 0.1 0.035 13.2 0.0 1.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 ORY70765.1 - 0.11 12.8 0.4 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY70765.1 - 0.11 13.0 0.6 0.55 10.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Gasdermin_C PF17708.1 ORY70765.1 - 0.11 12.5 5.1 0.2 11.7 5.1 1.4 1 0 0 1 1 1 0 Gasdermin PUB domain AAA_23 PF13476.6 ORY70765.1 - 0.12 12.9 7.7 5.6 7.4 6.2 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORY70765.1 - 1.7 8.7 5.1 7 6.7 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Arrestin_C PF02752.22 ORY70767.1 - 4.7e-20 72.4 0.0 8.9e-18 65.0 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY70767.1 - 1.9e-09 37.7 0.0 2.3e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY70767.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like CAF1-p150_C2 PF15539.6 ORY70767.1 - 0.025 14.1 0.6 0.068 12.6 0.6 1.7 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term Rgp1 PF08737.10 ORY70767.1 - 0.18 11.0 0.7 13 4.8 0.0 3.3 4 0 0 4 4 4 0 Rgp1 UCMA PF17085.5 ORY70767.1 - 4.2 7.4 5.1 9.1 6.3 5.1 1.5 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Abhydro_lipase PF04083.16 ORY70769.1 - 2.9e-16 58.8 0.4 1e-15 57.0 0.2 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ORY70769.1 - 2.3e-05 24.1 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY70769.1 - 0.00024 20.5 0.0 0.00059 19.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 MBOAT_2 PF13813.6 ORY70770.1 - 4.2e-07 30.1 0.1 0.0084 16.4 0.0 2.6 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family DUF908 PF06012.12 ORY70771.1 - 4.3e-100 335.6 0.0 4.3e-100 335.6 0.0 3.3 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 ORY70771.1 - 1.1e-98 330.7 0.0 1.1e-98 330.7 0.0 3.9 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) HECT PF00632.25 ORY70771.1 - 4.3e-88 295.7 0.0 7.1e-88 295.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 ORY70771.1 - 8.5e-31 104.5 22.2 4.1e-11 41.9 0.4 4.2 3 0 0 3 3 3 3 Ubiquitin binding region UBA PF00627.31 ORY70771.1 - 4.9e-10 39.1 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain FYVE PF01363.21 ORY70772.1 - 3.5e-11 43.1 1.3 5e-11 42.6 1.3 1.2 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 ORY70772.1 - 0.0077 16.4 4.7 0.011 15.9 4.7 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Myb_DNA-binding PF00249.31 ORY70773.1 - 5.5e-31 106.5 1.4 1.1e-16 60.8 0.7 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY70773.1 - 7.3e-23 80.6 1.4 3.7e-19 68.7 0.5 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY70773.1 - 0.00034 20.7 0.1 0.16 12.2 0.0 2.1 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 ORY70773.1 - 0.00045 20.2 0.0 0.44 10.6 0.0 2.1 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 ORY70773.1 - 0.0028 17.5 0.0 0.15 12.0 0.0 2.0 1 1 1 2 2 2 1 Myb DNA-binding like Spore_III_AB PF09548.10 ORY70773.1 - 0.051 13.7 0.1 0.06 13.4 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Rap1_C PF11626.8 ORY70773.1 - 0.064 13.3 0.3 0.2 11.8 0.1 1.8 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3905 PF13045.6 ORY70773.1 - 0.068 13.2 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3905) Vsr PF03852.15 ORY70773.1 - 0.079 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch endonuclease Vsr Myb_DNA-bind_4 PF13837.6 ORY70773.1 - 0.56 10.6 4.9 0.42 11.0 1.4 2.4 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Cullin PF00888.22 ORY70774.1 - 2.2e-168 561.7 0.0 3e-168 561.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY70774.1 - 5.7e-23 80.7 1.8 1.3e-22 79.6 1.8 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain SWIRM PF04433.17 ORY70775.1 - 7.2e-30 103.2 0.0 1.6e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 ORY70775.1 - 1.1e-19 70.2 5.4 2.3e-19 69.1 5.4 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 ORY70775.1 - 1.4e-09 38.0 0.0 3.2e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY70775.1 - 2.2e-06 27.8 0.0 5.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain FXMRP1_C_core PF12235.8 ORY70776.1 - 2.3 8.9 8.7 4.6 7.9 8.5 1.6 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal DUF5052 PF16475.5 ORY70778.1 - 0.41 10.3 3.7 0.52 9.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5052) Apt1 PF10351.9 ORY70779.1 - 0.84 8.4 6.7 1.1 8.1 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1180 PF06679.12 ORY70779.1 - 4.3 7.7 7.5 8 6.9 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 ORY70779.1 - 9.5 4.6 12.7 13 4.2 12.7 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_C1_2 PF03051.15 ORY70780.1 - 2.5e-158 527.5 1.7 1.2e-157 525.2 1.7 1.8 1 1 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 ORY70780.1 - 0.00071 19.7 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease CagX PF03524.15 ORY70780.1 - 0.13 11.9 0.2 1.1 8.9 0.2 2.1 2 0 0 2 2 2 0 Conjugal transfer protein DUF3774 PF12609.8 ORY70780.1 - 0.18 12.8 2.0 0.62 11.1 2.0 1.9 1 0 0 1 1 1 0 Wound-induced protein Sugar_transport PF06800.12 ORY70780.1 - 0.23 10.7 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Sugar transport protein SRP68 PF16969.5 ORY70781.1 - 7.2e-81 272.9 29.8 2.9e-80 270.9 25.1 2.0 2 0 0 2 2 2 2 RNA-binding signal recognition particle 68 YueH PF14166.6 ORY70781.1 - 0.78 9.6 2.5 1.5 8.7 0.6 2.5 2 0 0 2 2 2 0 YueH-like protein Dabb PF07876.12 ORY70783.1 - 3.1e-22 79.0 0.0 3.5e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain CPDase PF07823.11 ORY70784.1 - 1.1e-23 84.0 0.0 1.4e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 ORY70784.1 - 3.8e-12 46.4 0.0 5.2e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 ORY70784.1 - 1.4e-06 28.4 0.0 0.065 13.4 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase PPTA PF01239.22 ORY70785.1 - 2.6e-38 128.7 11.4 1.8e-10 40.2 0.3 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat PSP1 PF04468.12 ORY70787.1 - 1.9e-29 101.8 0.6 2.8e-29 101.2 0.6 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Aminotran_1_2 PF00155.21 ORY70789.1 - 3.6e-14 52.7 0.0 8.9e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Phosphodiest PF01663.22 ORY70791.1 - 6.3e-82 276.0 0.6 7.5e-82 275.8 0.6 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY70791.1 - 0.00029 20.4 0.0 0.032 13.6 0.0 2.2 2 0 0 2 2 2 2 Sulfatase FR47 PF08445.10 ORY70793.1 - 2.1e-09 37.2 0.1 3.2e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ORY70793.1 - 5.8e-06 26.5 0.0 9.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY70793.1 - 0.019 15.4 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SVIP PF15811.5 ORY70793.1 - 0.081 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Acetyltransf_10 PF13673.7 ORY70793.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5585 PF17823.1 ORY70794.1 - 0.0059 15.6 39.7 0.0072 15.3 39.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5585) Utp14 PF04615.13 ORY70794.1 - 6.3 5.2 9.8 7.5 5.0 9.8 1.0 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 ORY70794.1 - 9.7 3.2 14.0 11 2.9 14.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ino80_Iec3 PF14612.6 ORY70795.1 - 0.25 12.0 1.9 0.57 10.8 1.8 1.7 1 1 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_1 PF00076.22 ORY70796.1 - 3.8e-51 170.8 0.0 2.6e-18 65.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY70796.1 - 6e-06 25.9 0.0 0.2 11.2 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY70796.1 - 7.9e-06 25.7 0.0 0.00033 20.5 0.0 3.0 3 1 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY70796.1 - 6.5e-05 22.9 0.0 2 8.5 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY70796.1 - 0.0075 16.4 0.0 0.056 13.6 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif DUF4523 PF15023.6 ORY70796.1 - 0.058 13.2 0.0 8.6 6.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) CDK2AP PF09806.9 ORY70796.1 - 0.27 11.3 10.4 0.38 10.8 10.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ras PF00071.22 ORY70798.1 - 9.7e-65 217.1 0.1 1.1e-64 216.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY70798.1 - 3e-34 117.8 0.1 4.3e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY70798.1 - 6.5e-14 51.8 0.1 8.4e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY70798.1 - 3.8e-06 26.6 0.1 1.2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY70798.1 - 7.5e-05 22.2 0.0 8.9e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY70798.1 - 7.9e-05 22.6 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY70798.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY70798.1 - 0.014 15.2 0.1 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 ORY70798.1 - 0.037 13.6 0.0 2.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 ORY70798.1 - 0.037 14.4 0.0 0.05 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ORY70798.1 - 0.046 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF2157 PF09925.9 ORY70798.1 - 0.052 13.3 0.1 0.08 12.7 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) SRPRB PF09439.10 ORY70798.1 - 0.071 12.5 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 ORY70798.1 - 0.11 12.2 0.1 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY70798.1 - 0.12 12.9 0.0 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 ORY70798.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 ORY70798.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TB2_DP1_HVA22 PF03134.19 ORY70799.1 - 1.3e-27 95.6 6.5 1.6e-27 95.2 3.6 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Aminotran_4 PF01063.19 ORY70800.1 - 7.4e-30 104.5 0.0 1.1e-29 103.9 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV F-box-like PF12937.7 ORY70801.1 - 0.0014 18.5 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 ORY70805.1 - 8.4e-31 107.2 59.5 3.8e-24 85.3 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GET2 PF08690.10 ORY70806.1 - 3.8e-12 46.5 0.4 6.8e-11 42.4 0.4 2.6 1 1 0 1 1 1 1 GET complex subunit GET2 Pex19 PF04614.12 ORY70806.1 - 0.2 11.4 0.0 0.25 11.1 0.0 1.1 1 0 0 1 1 1 0 Pex19 protein family ArsA_ATPase PF02374.15 ORY70807.1 - 8.2e-109 363.5 0.1 9.5e-109 363.3 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 ORY70807.1 - 2.7e-13 50.1 0.0 5.1e-13 49.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY70807.1 - 2.7e-11 43.7 0.0 8.6e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 ORY70807.1 - 1e-05 25.1 0.0 2.6e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 ORY70807.1 - 1.3e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 ORY70807.1 - 2.2e-05 24.0 0.5 9.3e-05 22.0 0.3 1.9 1 1 1 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 ORY70807.1 - 4.2e-05 23.3 0.0 0.0003 20.5 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 ORY70807.1 - 0.0063 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.16 ORY70807.1 - 0.0094 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.6 ORY70807.1 - 0.023 14.3 0.3 0.095 12.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY70807.1 - 0.043 13.2 0.4 0.074 12.4 0.1 1.6 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 ORY70807.1 - 0.087 12.0 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 ORY70807.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Tad PF13400.6 ORY70808.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.0 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like DUF3742 PF12553.8 ORY70808.1 - 0.83 9.8 0.1 0.83 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) UL2 PF08196.11 ORY70808.1 - 5 7.2 7.7 5.9 6.9 0.9 2.4 2 0 0 2 2 2 0 UL2 protein SKN1 PF03935.15 ORY70810.1 - 2.2e-196 653.2 6.0 2.4e-196 653.0 6.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cellulase PF00150.18 ORY70811.1 - 5.3e-16 58.9 4.0 8.7e-16 58.2 4.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CPSF_A PF03178.15 ORY72192.1 - 2.6e-102 342.4 0.0 4.9e-102 341.5 0.0 1.4 2 0 0 2 2 2 1 CPSF A subunit region Glyco_transf_10 PF00852.19 ORY72193.1 - 3.9e-13 49.5 0.0 6.5e-11 42.3 0.0 2.5 2 1 0 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 ORY72193.1 - 0.023 15.1 0.0 0.054 14.0 0.0 1.6 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal Glyco_transf_10 PF00852.19 ORY72194.1 - 6.4e-19 68.3 0.0 1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Ribonucleas_3_3 PF14622.6 ORY72195.1 - 1e-09 38.6 0.1 1.3e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like F-box-like PF12937.7 ORY72196.1 - 0.00032 20.5 1.0 0.00084 19.2 1.0 1.8 1 0 0 1 1 1 1 F-box-like RNA_pol_3_Rpc31 PF11705.8 ORY72196.1 - 0.32 11.2 6.5 0.49 10.6 6.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Rhodanese PF00581.20 ORY72198.1 - 2.8e-13 50.3 0.0 3.5e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain F-box-like PF12937.7 ORY72203.1 - 1e-06 28.5 0.2 2.8e-06 27.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like Protoglobin PF11563.8 ORY72205.1 - 1.6e-34 119.1 0.0 2e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Protoglobin 6PF2K PF01591.18 ORY72206.1 - 7.7e-74 247.8 0.0 1.1e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY72206.1 - 7.1e-37 127.0 0.0 1.2e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY72206.1 - 2.1e-08 34.4 0.1 4.1e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORY72206.1 - 0.004 16.7 0.0 0.0068 15.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 ORY72206.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain GBP PF02263.19 ORY72206.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain TB2_DP1_HVA22 PF03134.19 ORY72207.1 - 1.6e-27 95.2 9.1 2.3e-27 94.7 9.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CENP-O PF09496.10 ORY72208.1 - 1.9e-16 60.7 0.0 3.4e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component TetR_C_28 PF17937.1 ORY72209.1 - 0.0055 17.1 0.3 0.023 15.1 0.3 2.0 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain XG_FTase PF03254.13 ORY72211.1 - 3e-10 39.3 0.0 0.00016 20.4 0.0 2.3 1 1 0 2 2 2 2 Xyloglucan fucosyltransferase NodZ PF05830.11 ORY72211.1 - 0.06 12.2 0.0 0.61 8.9 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) TPT PF03151.16 ORY72212.1 - 3.8e-17 62.6 24.9 4.6e-17 62.3 24.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY72212.1 - 4.6e-06 26.9 37.8 0.00024 21.3 14.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family Fumarate_red_C PF02300.17 ORY72212.1 - 0.41 10.7 7.6 0.63 10.1 0.4 2.6 2 1 0 2 2 2 0 Fumarate reductase subunit C SRR1 PF07985.12 ORY72215.1 - 7.1e-11 42.0 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 SRR1 DUF2986 PF11661.8 ORY72215.1 - 0.66 10.5 0.1 0.66 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2986) T6SS_TssG PF06996.11 ORY72216.1 - 0.00024 20.5 0.0 0.0004 19.7 0.0 1.3 1 1 0 1 1 1 1 Type VI secretion, TssG CK2S PF15011.6 ORY72216.1 - 0.0022 17.9 1.9 0.012 15.6 0.8 2.1 1 1 1 2 2 2 1 Casein Kinase 2 substrate PRA-PH PF01503.17 ORY72216.1 - 0.013 16.0 2.2 0.12 12.8 0.0 2.7 3 0 0 3 3 3 0 Phosphoribosyl-ATP pyrophosphohydrolase ABATE PF07336.11 ORY72216.1 - 0.047 14.4 0.8 0.61 10.8 0.8 2.3 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Rx_N PF18052.1 ORY72216.1 - 0.15 12.4 2.1 10 6.5 0.3 2.5 1 1 1 2 2 2 0 Rx N-terminal domain DASH_Duo1 PF08651.10 ORY72216.1 - 0.16 11.8 0.8 10 6.0 0.0 2.6 3 0 0 3 3 3 0 DASH complex subunit Duo1 Sec2p PF06428.11 ORY72216.1 - 0.27 11.2 2.8 17 5.5 0.0 2.8 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p DUF1664 PF07889.12 ORY72216.1 - 0.31 11.1 1.9 1.9 8.6 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) GAF_2 PF13185.6 ORY72217.1 - 1.3e-05 25.5 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ORY72217.1 - 7.6e-05 23.3 0.0 0.0001 22.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain Lipase_GDSL_2 PF13472.6 ORY72219.1 - 0.00012 22.5 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ATP12 PF07542.11 ORY72221.1 - 9.6e-40 135.6 0.0 1.6e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Coiled-coil_56 PF09813.9 ORY72222.1 - 0.00045 20.2 0.1 0.0011 19.0 0.0 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 56 CbiN PF02553.15 ORY72223.1 - 0.013 15.5 0.6 0.31 11.0 0.3 2.3 2 0 0 2 2 2 0 Cobalt transport protein component CbiN MFS_5 PF05631.14 ORY72224.1 - 1.4e-67 228.1 2.6 2.1e-67 227.5 2.6 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ORY72224.1 - 2.9e-19 69.2 30.8 1.2e-16 60.6 20.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4173 PF13777.6 ORY72224.1 - 0.034 13.6 4.6 1.3 8.4 1.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) DUF2681 PF10883.8 ORY72224.1 - 0.14 12.6 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Peptidase_M22 PF00814.25 ORY72226.1 - 2.4e-55 188.2 0.0 3e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 ORY72226.1 - 0.0013 18.4 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus Lipase_GDSL_2 PF13472.6 ORY72228.1 - 2.7e-24 86.6 0.0 3.8e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY72228.1 - 2.5e-12 47.2 0.0 4.3e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_5_C PF18564.1 ORY72229.1 - 1.9e-13 50.7 0.1 2.2e-11 44.1 0.0 2.5 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 ORY72229.1 - 1.3e-08 34.6 0.0 6.1e-08 32.4 0.0 2.0 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_14 PF01373.17 ORY72229.1 - 0.085 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 ORY72229.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DUF1180 PF06679.12 ORY72231.1 - 1.3 9.4 7.3 1.8 8.9 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) F-box-like PF12937.7 ORY72232.1 - 1e-07 31.7 0.1 2.8e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY72232.1 - 0.012 15.5 0.1 0.034 14.0 0.1 1.8 1 0 0 1 1 1 0 F-box domain WD40 PF00400.32 ORY72233.1 - 1.1e-59 197.0 19.6 5.1e-11 42.9 0.2 8.3 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY72233.1 - 2.6e-19 69.3 0.7 1.9e-07 31.2 0.0 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY72233.1 - 1.5e-09 37.1 15.5 0.013 14.2 0.0 6.4 5 3 3 8 8 8 4 Nucleoporin Nup120/160 LisH_TPL PF17814.1 ORY72233.1 - 0.00068 19.2 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 ORY72233.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 LisH bZIP_2 PF07716.15 ORY72233.1 - 0.23 11.6 0.1 0.46 10.6 0.1 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Ge1_WD40 PF16529.5 ORY72233.1 - 0.96 8.3 3.5 11 4.9 0.0 3.2 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIF_alpha PF05793.12 ORY72234.1 - 0.0012 17.5 3.1 0.0012 17.5 3.1 2.4 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 ORY72234.1 - 0.002 17.7 4.0 0.002 17.7 4.0 2.1 2 0 0 2 2 2 1 SDA1 BSP_II PF05432.11 ORY72234.1 - 0.0035 17.1 4.1 0.0035 17.1 4.1 1.9 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 ORY72234.1 - 0.85 7.8 17.1 0.088 11.1 3.0 2.3 2 0 0 2 2 2 0 CDC45-like protein Pkinase PF00069.25 ORY72235.1 - 7.8e-44 150.0 0.0 1.1e-43 149.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY72235.1 - 1.2e-42 146.0 0.0 1.8e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY72235.1 - 0.083 12.8 0.4 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY72235.1 - 0.11 11.3 0.3 0.29 9.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Draxin PF15550.6 ORY72238.1 - 3 7.6 30.3 3.2 7.6 26.8 2.2 2 0 0 2 2 2 0 Draxin His_Phos_1 PF00300.22 ORY72239.1 - 6.3e-33 114.1 3.7 2.1e-31 109.1 3.7 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DS PF01916.17 ORY72239.1 - 0.00045 19.5 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Deoxyhypusine synthase Aldo_ket_red PF00248.21 ORY72240.1 - 1.7e-141 470.6 0.0 1.1e-72 244.7 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family OmpH PF03938.14 ORY72240.1 - 0.018 15.4 0.1 4 7.8 0.0 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2250 PF10007.9 ORY72240.1 - 0.073 13.2 0.0 9.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Transket_pyr PF02779.24 ORY72241.1 - 3.3e-39 134.4 0.0 6.3e-39 133.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY72241.1 - 1.1e-27 96.4 0.0 2.7e-27 95.1 0.0 1.7 1 1 0 1 1 1 1 Transketolase, C-terminal domain RNA_pol_3_Rpc31 PF11705.8 ORY72243.1 - 2.6e-16 60.6 16.4 5.8e-16 59.4 16.4 1.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 LRR_8 PF13855.6 ORY72244.1 - 0.03 14.1 0.8 0.46 10.3 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat ADH_N PF08240.12 ORY72245.1 - 4.7e-28 97.2 0.3 7.8e-28 96.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY72245.1 - 9e-27 93.6 0.0 1.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY72245.1 - 2.7e-06 28.5 0.0 5.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY72245.1 - 0.0098 15.4 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase TOBE_2 PF08402.10 ORY72245.1 - 0.031 14.4 0.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 TOBE domain ACP_syn_III_C PF08541.10 ORY72245.1 - 0.046 13.9 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AIRC PF00731.20 ORY72245.1 - 0.09 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 AIR carboxylase RuBisCO_large PF00016.20 ORY72245.1 - 0.13 11.5 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Cloacin PF03515.14 ORY72245.1 - 0.14 11.8 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain Fungal_trans PF04082.18 ORY72246.1 - 5.8e-20 71.4 0.0 8.7e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY72246.1 - 3.1e-06 27.2 9.8 6.5e-06 26.2 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 ORY72247.1 - 9e-07 28.5 0.1 2.9e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 Dioxygenase SnoaL_4 PF13577.6 ORY72247.1 - 6 7.0 6.9 1.4 9.0 2.3 2.3 2 1 0 2 2 2 0 SnoaL-like domain Thiamine_BP PF01910.17 ORY72248.1 - 1.5e-30 105.0 0.0 1.8e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Ykof PF07615.11 ORY72248.1 - 0.011 16.1 0.0 0.017 15.6 0.0 1.3 1 0 0 1 1 1 0 YKOF-related Family DUF3791 PF12668.7 ORY72248.1 - 0.21 11.7 0.0 2 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) MRP-S28 PF10213.9 ORY72249.1 - 7.3e-39 133.1 0.2 9.7e-39 132.7 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein LEA_2 PF03168.13 ORY72250.1 - 0.00026 21.5 0.1 0.00051 20.5 0.1 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF2749 PF10907.8 ORY72250.1 - 0.078 13.2 0.6 0.22 11.7 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) GFA PF04828.14 ORY72251.1 - 4.3e-20 71.9 0.1 6.2e-20 71.3 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme LtrA PF06772.11 ORY72252.1 - 3.7e-32 111.9 22.7 5.5e-31 108.1 22.7 2.0 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Pkinase PF00069.25 ORY72253.1 - 3.6e-26 92.1 0.0 4.1e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY72253.1 - 1.4e-12 47.4 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY72253.1 - 1.8e-08 33.6 0.0 2.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY72253.1 - 0.0025 17.8 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family ADH_N PF08240.12 ORY72254.1 - 4.7e-28 97.2 0.3 7.8e-28 96.5 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY72254.1 - 9e-27 93.6 0.0 1.5e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY72254.1 - 2.7e-06 28.5 0.0 5.4e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY72254.1 - 0.0098 15.4 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase TOBE_2 PF08402.10 ORY72254.1 - 0.031 14.4 0.1 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 TOBE domain ACP_syn_III_C PF08541.10 ORY72254.1 - 0.046 13.9 0.1 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AIRC PF00731.20 ORY72254.1 - 0.09 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 AIR carboxylase RuBisCO_large PF00016.20 ORY72254.1 - 0.13 11.5 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Cloacin PF03515.14 ORY72254.1 - 0.14 11.8 0.1 0.2 11.3 0.1 1.2 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain F-box-like PF12937.7 ORY72255.1 - 1e-05 25.3 0.3 2.1e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 F-box-like Exostosin PF03016.15 ORY72257.1 - 3.3e-32 111.9 0.0 5e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DUF1979 PF09322.10 ORY72257.1 - 0.092 12.7 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) MFS_1 PF07690.16 ORY72258.1 - 4.3e-09 35.7 21.5 5.4e-09 35.4 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY72258.1 - 1.5e-06 27.4 0.2 1.5e-06 27.4 0.2 1.5 2 0 0 2 2 2 1 Sugar (and other) transporter CIMR PF00878.18 ORY72379.1 - 1.8e-10 41.0 0.1 1.5e-08 34.8 0.1 2.0 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat LPAM_1 PF08139.12 ORY72379.1 - 0.02 15.3 0.7 0.036 14.6 0.7 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site PepSY_2 PF13670.6 ORY72379.1 - 0.64 10.1 1.8 2.6 8.1 1.8 2.0 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain INCENP_ARK-bind PF03941.15 ORY72380.1 - 0.052 13.5 0.6 0.16 11.9 0.6 1.8 1 0 0 1 1 1 0 Inner centromere protein, ARK binding region Arm PF00514.23 ORY72381.1 - 0.018 15.1 0.6 0.095 12.8 0.6 2.4 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY72381.1 - 1.4 9.5 11.7 0.76 10.3 0.7 4.3 4 1 1 5 5 5 0 HEAT-like repeat Fasciclin PF02469.22 ORY72382.1 - 0.0023 18.2 0.0 0.0055 16.9 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain Ribosomal_L2_C PF03947.18 ORY72384.1 - 3.4e-49 166.2 1.1 9.5e-49 164.8 1.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY72384.1 - 3.4e-25 87.8 0.5 6.7e-25 86.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.16 ORY72385.1 - 2.2e-12 46.6 49.5 2.3e-10 40.0 40.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Lgl_C PF08596.10 ORY72386.1 - 3.7e-27 95.0 0.0 1.7e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 ORY72386.1 - 4.6e-09 36.4 0.0 0.0029 17.9 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY72386.1 - 2.8e-08 34.3 0.1 0.24 12.3 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Synaptobrevin PF00957.21 ORY72386.1 - 0.014 15.2 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Synaptobrevin ATP-synt_G PF04718.15 ORY72387.1 - 3.5e-14 53.4 2.3 4.1e-14 53.2 0.4 1.9 1 1 1 2 2 2 1 Mitochondrial ATP synthase g subunit Tape_meas_lam_C PF09718.10 ORY72387.1 - 0.078 13.1 1.3 5.1 7.3 0.1 2.8 1 1 2 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Complex1_49kDa PF00346.19 ORY72390.1 - 2.4e-121 404.0 0.0 3e-121 403.6 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 ORY72390.1 - 0.001 18.0 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase PXA PF02194.15 ORY72392.1 - 9.4e-50 169.1 0.0 2.2e-49 167.9 0.0 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 ORY72392.1 - 2.3e-26 92.6 0.1 1e-25 90.5 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 ORY72392.1 - 4.2e-17 62.1 0.0 1.6e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 PX domain RGS PF00615.19 ORY72392.1 - 3.2e-11 43.5 0.1 6.2e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain Isy1 PF06246.12 ORY72392.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Isy1-like splicing family GST_N PF02798.20 ORY72394.1 - 9.8e-14 51.5 0.0 1.9e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY72394.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY72394.1 - 2.2e-10 40.6 0.0 4.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY72394.1 - 4.6e-10 39.8 0.0 8.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY72394.1 - 6.2e-08 32.5 0.0 1.2e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY72394.1 - 5.2e-07 29.9 0.1 1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ORY72394.1 - 0.0036 17.1 0.0 0.0074 16.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY72394.1 - 0.075 12.9 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain zf-C2H2 PF00096.26 ORY72395.1 - 5.6e-07 29.7 1.4 0.011 16.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY72395.1 - 2.3e-05 24.9 1.9 0.017 15.9 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY72395.1 - 0.00035 20.8 0.9 0.16 12.3 0.2 2.4 1 1 1 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORY72395.1 - 0.0008 19.6 0.8 0.18 12.1 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding HTH_Tnp_1 PF01527.20 ORY72395.1 - 0.045 14.1 0.8 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Transposase Ima1_N PF09779.9 ORY72395.1 - 0.058 14.2 1.0 0.13 13.1 0.9 1.5 1 1 0 1 1 1 0 Ima1 N-terminal domain HypA PF01155.19 ORY72395.1 - 0.078 13.0 0.3 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_clus PF00172.18 ORY72396.1 - 3.7e-06 27.0 7.1 5.7e-06 26.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY72396.1 - 0.00035 19.7 0.7 0.0005 19.2 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nop52 PF05997.12 ORY72397.1 - 8e-64 215.4 0.0 1.1e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 HEAT_EZ PF13513.6 ORY72397.1 - 0.06 13.9 0.0 6.4 7.4 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat UDPGP PF01704.18 ORY72398.1 - 6.9e-53 179.8 0.0 9.1e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORY72398.1 - 0.0079 16.6 0.0 0.016 15.5 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain Aldedh PF00171.22 ORY72399.1 - 3.1e-125 418.3 0.1 3.8e-125 418.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.28 ORY72401.1 - 5.2e-83 279.0 0.0 6.5e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY72401.1 - 3.9e-17 63.0 0.0 8.3e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORY72401.1 - 2.5e-09 36.9 0.9 9.6e-09 35.0 0.1 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus CDP-OH_P_transf PF01066.21 ORY72402.1 - 4.4e-18 65.8 0.0 4.4e-18 65.8 0.0 3.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Aldolase_II PF00596.21 ORY72403.1 - 2.2e-42 145.1 0.0 2.7e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TFIIIC_sub6 PF10419.9 ORY72404.1 - 1.1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain API5 PF05918.11 ORY72404.1 - 1.7 7.4 11.7 2.1 7.1 11.7 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Aldedh PF00171.22 ORY72407.1 - 4.2e-126 421.2 0.1 5e-126 420.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2236 PF09995.9 ORY72408.1 - 8.5e-30 104.6 3.9 1.5e-29 103.9 3.9 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Bac_luciferase PF00296.20 ORY72410.1 - 8.3e-57 193.0 0.9 1.1e-56 192.5 0.9 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Na_Ca_ex PF01699.24 ORY72411.1 - 9.7e-40 136.0 39.2 2.6e-21 76.1 12.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CMD PF02627.20 ORY72412.1 - 0.0018 18.3 0.6 0.013 15.6 0.1 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family HMGL-like PF00682.19 ORY72413.1 - 2.5e-44 151.8 0.0 1.9e-43 148.9 0.0 2.0 1 1 0 1 1 1 1 HMGL-like Cpn60_TCP1 PF00118.24 ORY72414.1 - 6.9e-168 559.3 1.0 7.8e-168 559.1 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ATG101 PF07855.12 ORY72415.1 - 4.8e-33 114.3 0.0 5.8e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 HgmA PF04209.13 ORY72416.1 - 1.1e-176 587.8 0.1 1.2e-176 587.6 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAD_binding_3 PF01494.19 ORY72417.1 - 9.6e-13 48.1 2.5 1.4e-11 44.2 2.5 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY72417.1 - 1.5e-06 28.0 5.4 0.0026 17.4 2.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY72417.1 - 0.00011 21.4 1.2 0.00024 20.3 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY72417.1 - 0.00067 19.8 0.6 0.0018 18.4 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY72417.1 - 0.026 13.7 5.2 0.063 12.5 0.8 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY72417.1 - 0.033 13.0 2.5 0.12 11.2 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 ORY72417.1 - 0.044 12.5 2.1 0.12 11.0 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 ORY72417.1 - 0.07 12.2 1.1 0.094 11.8 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY72417.1 - 0.77 8.9 3.4 0.87 8.8 1.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NIPSNAP PF07978.13 ORY72418.1 - 2.7e-31 107.8 1.4 1.4e-24 86.3 0.2 2.3 2 0 0 2 2 2 2 NIPSNAP Asp PF00026.23 ORY72419.1 - 4.7e-59 200.4 3.5 5.5e-59 200.1 3.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY72419.1 - 2.5e-12 47.4 2.8 2.4e-06 27.9 0.2 3.2 2 1 1 3 3 3 3 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ORY72419.1 - 0.076 13.6 0.1 15 6.3 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Carboxyl_trans PF01039.22 ORY72420.1 - 6e-134 447.4 0.2 7e-134 447.1 0.2 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.14 ORY72420.1 - 0.2 11.5 0.1 20 5.0 0.0 3.0 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PALP PF00291.25 ORY72421.1 - 4.4e-61 206.9 0.2 5.3e-61 206.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VWA PF00092.28 ORY72421.1 - 0.002 18.4 0.0 0.087 13.1 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Methyltransf_12 PF08242.12 ORY72421.1 - 0.011 16.5 0.0 0.03 15.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORY72421.1 - 0.16 12.7 0.0 0.36 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MoaC PF01967.21 ORY72422.1 - 1.3e-47 161.3 0.7 2.1e-47 160.6 0.7 1.4 1 0 0 1 1 1 1 MoaC family Radical_SAM PF04055.21 ORY72422.1 - 1.9e-28 99.9 0.0 5.8e-28 98.4 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Mob_synth_C PF06463.13 ORY72422.1 - 5.8e-28 97.4 0.0 9.6e-28 96.7 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Fer4_12 PF13353.6 ORY72422.1 - 1.1e-05 25.8 0.0 2.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORY72422.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain UQ_con PF00179.26 ORY72423.1 - 9.5e-40 135.5 0.0 1.2e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme I-set PF07679.16 ORY72424.1 - 0.21 11.7 1.1 12 6.0 0.0 3.9 6 0 0 6 6 6 0 Immunoglobulin I-set domain TAL_FSA PF00923.19 ORY72425.1 - 1.1e-35 123.4 0.0 1.3e-35 123.2 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Pkinase PF00069.25 ORY72426.1 - 1.5e-09 37.7 0.0 1.7e-08 34.2 0.0 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY72426.1 - 5.5e-09 35.7 0.0 2.3e-08 33.6 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase adh_short PF00106.25 ORY72427.1 - 3.2e-31 108.3 0.8 5.8e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY72427.1 - 1.1e-23 84.1 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY72427.1 - 0.012 15.5 4.0 0.021 14.7 0.3 2.7 2 1 0 2 2 2 0 KR domain 2-Hacid_dh_C PF02826.19 ORY72427.1 - 0.02 14.3 0.5 1 8.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY72427.1 - 0.057 13.3 0.4 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORY72427.1 - 0.12 13.1 0.1 0.24 12.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M24 PF00557.24 ORY72428.1 - 2.3e-16 60.1 0.3 3.4e-16 59.6 0.3 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Adeno_PIX PF03955.14 ORY72428.1 - 0.054 13.7 0.5 0.21 11.7 0.5 2.0 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) zf-MYND PF01753.18 ORY72429.1 - 1.8e-10 40.7 7.3 1.8e-10 40.7 7.3 1.8 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 ORY72429.1 - 0.17 12.2 3.0 0.34 11.2 3.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3074 PF11274.8 ORY72430.1 - 1.2e-23 84.1 0.1 1.8e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Transthyretin PF00576.21 ORY72431.1 - 9.8e-41 138.9 0.0 1.1e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family TTR-52 PF01060.23 ORY72431.1 - 0.029 15.1 0.1 0.52 11.1 0.1 2.1 1 1 0 1 1 1 0 Transthyretin-like family bMG3 PF11974.8 ORY72431.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Ion_trans PF00520.31 ORY72432.1 - 1.6e-06 27.5 1.7 2e-06 27.2 1.7 1.1 1 0 0 1 1 1 1 Ion transport protein NAD_binding_10 PF13460.6 ORY72432.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Fib_alpha PF08702.10 ORY72433.1 - 0.0032 17.6 13.1 0.013 15.7 0.8 3.4 3 0 0 3 3 3 2 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 ORY72433.1 - 0.0093 16.3 0.3 0.0093 16.3 0.3 3.7 3 1 1 4 4 4 1 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 ORY72433.1 - 0.045 14.2 4.8 0.064 13.7 0.2 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BBP1_C PF15272.6 ORY72433.1 - 0.076 12.8 0.1 0.076 12.8 0.1 3.3 4 0 0 4 4 4 0 Spindle pole body component BBP1, C-terminal HCMV_UL139 PF12507.8 ORY72433.1 - 0.24 11.8 4.0 0.27 11.6 0.0 2.7 3 0 0 3 3 3 0 Human Cytomegalovirus UL139 protein Baculo_PEP_C PF04513.12 ORY72433.1 - 0.37 10.8 4.3 14 5.8 0.4 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 ORY72433.1 - 2.9 8.6 12.0 23 5.7 0.3 3.6 3 0 0 3 3 3 0 Initiation control protein YabA DUF2730 PF10805.8 ORY72433.1 - 7.6 6.7 7.0 0.79 9.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) SHE3 PF17078.5 ORY72433.1 - 8.3 6.1 11.4 0.4 10.4 0.3 3.1 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 PIN_12 PF16289.5 ORY72433.1 - 9.6 6.7 9.5 0.4 11.2 0.2 2.6 3 0 0 3 3 3 0 PIN domain ABC_tran_CTD PF16326.5 ORY72434.1 - 0.018 15.3 2.8 0.024 14.9 1.4 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain KLRAQ PF10205.9 ORY72434.1 - 0.056 13.7 0.9 0.081 13.2 0.9 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein FliT PF05400.13 ORY72434.1 - 0.07 14.0 4.5 0.33 11.8 2.6 2.3 2 0 0 2 2 2 0 Flagellar protein FliT TMF_TATA_bd PF12325.8 ORY72434.1 - 0.1 12.8 3.0 0.26 11.5 2.5 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 ORY72434.1 - 0.51 10.8 7.9 22 5.6 0.8 3.2 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 adh_short PF00106.25 ORY72435.1 - 1.3e-34 119.4 0.1 2e-34 118.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY72435.1 - 1.3e-25 90.3 0.1 2.1e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY72435.1 - 0.0004 20.4 2.5 0.005 16.8 2.5 2.1 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY72435.1 - 0.17 11.7 1.7 0.37 10.7 1.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain His_biosynth PF00977.21 ORY72436.1 - 2.7e-43 148.1 0.0 5.5e-41 140.5 0.0 4.1 2 1 1 3 3 3 1 Histidine biosynthesis protein GATase PF00117.28 ORY72436.1 - 2.8e-19 69.6 0.0 4.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ORY72436.1 - 6.2e-10 39.0 0.0 1.6e-09 37.6 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 ORY72436.1 - 1.7e-05 24.8 0.0 0.0021 17.9 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_S51 PF03575.17 ORY72436.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 TMP-TENI PF02581.17 ORY72436.1 - 0.055 12.8 0.0 3.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase Dus PF01207.17 ORY72436.1 - 0.15 11.2 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) 2-Hacid_dh_C PF02826.19 ORY72437.1 - 3.3e-51 173.2 0.0 1.6e-50 171.0 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY72437.1 - 3.1e-30 104.5 0.0 4.1e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 ORY72437.1 - 0.0046 17.0 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 ORY72437.1 - 0.017 15.3 0.1 0.078 13.1 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Oxidored_nitro PF00148.19 ORY72437.1 - 0.14 10.8 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase BATS PF06968.13 ORY72438.1 - 6.1e-23 80.8 0.3 1.8e-21 76.1 0.0 2.6 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ORY72438.1 - 3.9e-14 53.4 0.2 7.3e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily AAA_18 PF13238.6 ORY72439.1 - 4.1e-07 30.6 0.2 0.00089 19.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain PRK PF00485.18 ORY72439.1 - 1e-05 25.3 0.0 0.029 14.1 0.0 2.1 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ORY72439.1 - 6e-05 23.2 0.1 0.021 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 ORY72439.1 - 0.0029 16.6 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 ORY72439.1 - 0.014 14.5 0.0 0.026 13.6 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 ORY72439.1 - 0.023 14.0 0.1 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 ORY72439.1 - 0.024 15.0 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 ORY72439.1 - 0.044 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ORY72439.1 - 0.06 12.5 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain KTI12 PF08433.10 ORY72439.1 - 0.073 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 ORY72439.1 - 0.093 13.2 0.2 0.33 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ORY72439.1 - 0.099 12.5 0.0 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase NACHT PF05729.12 ORY72439.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 ORY72439.1 - 0.22 12.0 0.0 0.4 11.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 ORY72439.1 - 0.22 11.2 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain IBN_N PF03810.19 ORY72440.1 - 3.4e-12 46.1 0.0 5e-11 42.4 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 ORY72440.1 - 4.8e-06 26.9 0.4 1.2 9.6 0.1 4.0 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 ORY72440.1 - 3.4e-05 23.7 1.2 3.2 8.3 0.1 5.3 4 0 0 4 4 4 2 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY72440.1 - 0.0022 18.5 0.0 0.67 10.6 0.0 3.3 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region Xpo1 PF08389.12 ORY72440.1 - 0.0063 16.6 0.1 0.097 12.7 0.0 3.1 2 0 0 2 2 2 1 Exportin 1-like protein HEAT_EZ PF13513.6 ORY72440.1 - 0.025 15.1 7.0 1.9 9.1 0.2 4.8 5 0 0 5 5 5 0 HEAT-like repeat RIX1 PF08167.12 ORY72440.1 - 0.078 12.7 0.4 3.4 7.4 0.0 3.2 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis API5 PF05918.11 ORY72440.1 - 0.13 11.0 0.3 0.27 10.0 0.3 1.5 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Cnd1 PF12717.7 ORY72440.1 - 0.14 12.1 0.5 0.44 10.6 0.4 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF2457 PF10446.9 ORY72440.1 - 8 5.5 11.9 12 4.9 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Prefoldin_2 PF01920.20 ORY72441.1 - 3.5e-20 71.9 9.1 3.5e-20 71.9 9.1 1.7 1 1 1 2 2 2 1 Prefoldin subunit End3 PF12761.7 ORY72441.1 - 0.02 15.1 6.0 0.027 14.7 6.0 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Peptidase_S46 PF10459.9 ORY72441.1 - 0.031 12.9 6.3 0.035 12.8 6.3 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF4239 PF14023.6 ORY72441.1 - 0.061 13.0 0.3 0.076 12.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Bcr-Abl_Oligo PF09036.10 ORY72441.1 - 0.065 13.2 1.0 0.065 13.2 1.0 1.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DHR10 PF18595.1 ORY72441.1 - 0.071 13.2 13.6 0.66 10.0 0.6 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 ORY72441.1 - 0.15 12.1 12.4 0.047 13.7 6.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 ORY72441.1 - 0.19 12.2 6.1 0.56 10.7 2.1 2.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 ORY72441.1 - 0.19 10.6 11.6 0.26 10.1 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) USP8_interact PF08941.10 ORY72441.1 - 0.29 10.9 6.9 0.28 11.0 0.3 2.0 1 1 1 2 2 2 0 USP8 interacting Spc24 PF08286.11 ORY72441.1 - 0.32 11.3 10.1 0.53 10.6 3.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 ORY72441.1 - 0.39 11.4 9.3 2.3 8.9 0.8 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Lge1 PF11488.8 ORY72441.1 - 0.73 10.1 6.4 1.8 8.8 6.4 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Fib_alpha PF08702.10 ORY72441.1 - 0.86 9.8 7.8 2 8.6 7.8 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC53 PF10152.9 ORY72441.1 - 0.96 9.9 7.7 0.2 12.0 1.3 2.0 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex Atg14 PF10186.9 ORY72441.1 - 1.2 8.1 8.1 1.7 7.7 8.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 ORY72441.1 - 2 8.8 13.5 0.44 11.0 2.8 2.1 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 ORY72441.1 - 3.4 8.1 7.7 3.6 8.1 1.4 3.3 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 ORY72441.1 - 3.9 7.8 12.0 2.6 8.4 4.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF4407 PF14362.6 ORY72441.1 - 4.4 6.6 9.9 15 4.8 9.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 ORY72441.1 - 4.7 5.0 6.7 6.1 4.6 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family THOC7 PF05615.13 ORY72441.1 - 5 7.4 11.6 14 6.0 11.6 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 ABC_tran_CTD PF16326.5 ORY72441.1 - 5 7.4 13.7 4.4 7.6 5.5 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 ORY72441.1 - 7.4 7.1 16.2 2.4e+02 2.2 16.2 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 ORY72441.1 - 7.5 6.6 12.9 25 4.9 12.9 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1192 PF06698.11 ORY72441.1 - 9.6 6.4 7.8 5.7 7.1 0.5 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1192) NAD_binding_2 PF03446.15 ORY72442.1 - 1.8e-19 70.4 0.0 3e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY72442.1 - 2.1e-09 37.7 0.0 3.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORY72442.1 - 0.0043 17.6 0.0 0.015 15.8 0.0 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORY72442.1 - 0.0043 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ORY72442.1 - 0.0057 16.0 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pex14_N PF04695.13 ORY72443.1 - 0.015 16.0 14.7 0.019 15.6 14.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 ORY72443.1 - 0.033 14.2 2.2 0.032 14.2 2.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 ORY72443.1 - 2.3 8.1 12.4 2.9 7.7 12.4 1.2 1 0 0 1 1 1 0 SPX domain DUF1304 PF06993.12 ORY72444.1 - 0.048 13.7 0.6 0.048 13.7 0.6 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) AA_kinase PF00696.28 ORY72556.1 - 2.7e-35 122.1 0.3 3.2e-35 121.9 0.3 1.0 1 0 0 1 1 1 1 Amino acid kinase family DUF727 PF05303.12 ORY72557.1 - 1.1e-07 31.9 0.0 1.6e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) Thioredoxin PF00085.20 ORY72559.1 - 1.5e-27 95.6 0.1 1.8e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY72559.1 - 4e-06 27.3 0.2 7.9e-05 23.1 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY72559.1 - 7.2e-05 23.0 0.0 0.00017 21.8 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 ORY72559.1 - 8e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ORY72559.1 - 0.00039 20.3 0.0 0.00067 19.6 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ORY72559.1 - 0.00072 19.7 0.1 0.0018 18.4 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 ORY72559.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 1 0 1 1 1 0 Redoxin DIM1 PF02966.16 ORY72559.1 - 0.027 14.2 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_9 PF14595.6 ORY72559.1 - 0.034 13.9 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 ORY72559.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin DUF2847 PF11009.8 ORY72559.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) PCYCGC PF13798.6 ORY72559.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif TraF PF13728.6 ORY72559.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Syja_N PF02383.18 ORY72560.1 - 9e-69 232.2 0.0 1.3e-68 231.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain adh_short PF00106.25 ORY72561.1 - 1.9e-27 96.0 0.0 2.8e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY72561.1 - 7.7e-26 91.1 0.0 1.2e-25 90.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY72561.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.5 1 1 0 1 1 1 1 KR domain Citrate_bind PF16114.5 ORY72561.1 - 0.015 14.8 0.0 0.22 11.0 0.0 2.1 1 1 1 2 2 2 0 ATP citrate lyase citrate-binding DUF460 PF04312.13 ORY72561.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF460) UPF0175 PF03683.13 ORY72562.1 - 0.00039 20.1 0.1 0.0017 18.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0175) MAP65_ASE1 PF03999.12 ORY72562.1 - 0.044 12.5 2.8 0.077 11.7 2.8 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) zf-C3HC4_3 PF13920.6 ORY72562.1 - 0.12 12.2 8.5 0.23 11.3 8.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FKBP_N PF01346.18 ORY72562.1 - 0.7 10.9 5.2 16 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Carla_C4 PF01623.17 ORY72562.1 - 9.1 6.3 7.5 0.41 10.6 1.5 1.8 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein zf-MYND PF01753.18 ORY72564.1 - 0.015 15.4 1.2 0.032 14.3 1.2 1.4 1 0 0 1 1 1 0 MYND finger ASFV_J13L PF05568.11 ORY72564.1 - 0.46 10.2 3.4 4.5 7.0 0.8 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein E1-E2_ATPase PF00122.20 ORY72565.1 - 2.6e-47 160.7 4.2 5.9e-47 159.5 4.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY72565.1 - 8.3e-40 137.3 0.6 1e-38 133.7 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORY72565.1 - 8.7e-28 96.6 0.0 3.6e-13 49.7 0.0 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ORY72565.1 - 4.1e-06 26.7 0.5 0.0001 22.1 0.2 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY72565.1 - 0.0051 17.2 0.5 0.061 13.7 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase SLT PF01464.20 ORY72566.1 - 1e-09 38.0 0.0 3.1e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Transglycosylase SLT domain Spp-24 PF07448.11 ORY72566.1 - 0.11 12.7 0.0 5.4 7.3 0.1 2.7 2 0 0 2 2 2 0 Secreted phosphoprotein 24 (Spp-24) cystatin-like domain MCM_bind PF09739.9 ORY72566.1 - 0.13 10.7 3.4 0.16 10.4 3.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MDM10 PF12519.8 ORY72566.1 - 1.4 7.7 9.2 2 7.2 9.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF966 PF06136.13 ORY72566.1 - 2.7 7.6 13.5 3.5 7.2 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC27 PF09507.10 ORY72566.1 - 4.7 6.5 31.5 6.2 6.1 31.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Draxin PF15550.6 ORY72566.1 - 5.5 6.8 10.4 7.5 6.3 10.4 1.2 1 0 0 1 1 1 0 Draxin DUF572 PF04502.13 ORY72566.1 - 7.3 6.1 20.1 11 5.5 20.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOBP PF15279.6 ORY72566.1 - 8.3 6.9 5.3 13 6.2 5.3 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 ORY72566.1 - 8.7 4.9 8.7 11 4.6 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IHO1 PF15771.5 ORY72566.1 - 9.3 4.9 18.3 13 4.4 18.3 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 CENP-C_C PF11699.8 ORY72568.1 - 5.5e-25 87.4 0.1 9e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 ORY72568.1 - 1.2e-05 25.0 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORY72568.1 - 0.022 14.7 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ATP-synt_ab PF00006.25 ORY72569.1 - 9.4e-110 365.3 0.0 1.3e-109 364.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 ORY72569.1 - 1.9e-43 147.2 0.0 3.5e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 ORY72569.1 - 8.3e-14 51.9 1.3 2e-13 50.7 1.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DnaJ_C PF01556.18 ORY72570.1 - 7.7e-29 100.7 0.0 1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY72570.1 - 1.1e-25 89.5 4.6 5.8e-25 87.2 2.4 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY72570.1 - 9.4e-14 51.5 12.1 1.7e-13 50.7 12.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY72570.1 - 4.7e-06 26.5 4.0 0.02 14.8 0.7 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORY72570.1 - 0.00018 21.5 4.4 0.26 11.3 0.1 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 ORY72570.1 - 1.2 9.5 5.2 0.58 10.6 2.3 2.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.6 ORY72570.1 - 2.4 8.1 6.7 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORY72570.1 - 5.4 7.2 7.7 2.9 8.1 4.1 2.1 1 1 1 2 2 2 0 zinc RING finger of MSL2 Hat1_N PF10394.9 ORY72571.1 - 3.2e-49 167.3 0.0 6.2e-49 166.3 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 ORY72571.1 - 6.6e-06 26.3 0.0 1.6e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 ORY72571.1 - 0.00015 21.5 0.1 0.00025 20.8 0.1 1.5 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.7 ORY72571.1 - 0.006 17.0 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.26 ORY72572.1 - 1.2e-16 60.9 0.1 2e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY72572.1 - 1.1e-13 52.4 0.0 2.5e-13 51.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY72572.1 - 6.4e-10 38.9 0.0 1.5e-09 37.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF4072 PF13284.6 ORY72572.1 - 0.08 13.4 0.2 0.18 12.3 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4072) NatB_MDM20 PF09797.9 ORY72573.1 - 2.6e-70 237.3 1.1 5.2e-70 236.3 0.1 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit RB_A PF01858.17 ORY72573.1 - 0.077 12.8 0.4 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein A domain AMP-binding PF00501.28 ORY72574.1 - 1.3e-07 30.6 0.0 3.4e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme zf-MYND PF01753.18 ORY72575.1 - 1.9e-09 37.5 12.2 3.7e-09 36.5 12.2 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY72575.1 - 1.3 9.4 7.5 3.2 8.1 7.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding UCH PF00443.29 ORY72576.1 - 1.3e-37 129.7 0.0 2.5e-37 128.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY72576.1 - 5.1e-19 69.0 0.1 2.7e-18 66.6 0.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORY72576.1 - 5.2e-09 35.7 0.3 1.2e-08 34.6 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 ORY72576.1 - 0.00017 22.2 0.0 0.11 13.1 0.0 2.7 2 0 0 2 2 2 2 DUSP domain Rad60-SLD PF11976.8 ORY72576.1 - 0.093 12.6 0.2 0.28 11.0 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glyco_hydro2_C5 PF18565.1 ORY72576.1 - 0.11 12.4 0.4 0.42 10.5 0.1 2.2 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 OTU PF02338.19 ORY72577.1 - 5.2e-06 27.0 0.0 9.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 ORY72577.1 - 0.035 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family UN_NPL4 PF11543.8 ORY72577.1 - 0.052 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF1187 PF06688.11 ORY72577.1 - 0.14 12.5 0.2 0.26 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) Ubiquitin_2 PF14560.6 ORY72577.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain MSA-2c PF12238.8 ORY72577.1 - 8.9 6.3 8.3 15 5.5 8.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c CAP_N PF01213.19 ORY72578.1 - 7.9e-104 347.5 2.0 7.9e-104 347.5 2.0 1.5 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 ORY72578.1 - 1.3e-57 193.8 5.2 1.7e-57 193.4 5.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Prp31_C PF09785.9 ORY72579.1 - 0.012 16.5 2.0 0.023 15.6 2.0 1.3 1 0 0 1 1 1 0 Prp31 C terminal domain F-box-like PF12937.7 ORY72579.1 - 0.046 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.16 ORY72580.1 - 1.3e-21 76.9 33.4 1.3e-12 47.3 16.3 2.9 3 1 0 3 3 3 2 Major Facilitator Superfamily DUF5326 PF17260.2 ORY72580.1 - 0.022 14.9 5.4 2.8 8.2 0.5 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5326) OATP PF03137.20 ORY72580.1 - 0.3 9.3 2.0 1.3 7.2 1.8 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cu_bind_like PF02298.17 ORY72581.1 - 2.3e-05 24.3 0.0 0.0001 22.2 0.0 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 ORY72581.1 - 0.0016 18.8 0.1 0.0038 17.7 0.1 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family V_ATPase_I PF01496.19 ORY72582.1 - 0 1034.3 0.0 0 1034.1 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 ORY72582.1 - 0.015 15.2 1.3 0.095 12.7 0.2 2.4 2 0 0 2 2 2 0 Prefoldin subunit CheZ PF04344.13 ORY72582.1 - 0.079 12.9 0.5 0.25 11.2 0.2 1.9 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Snapin_Pallidin PF14712.6 ORY72582.1 - 0.17 12.3 0.6 9.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Snapin/Pallidin SlyX PF04102.12 ORY72582.1 - 0.2 12.3 2.8 44 4.8 0.4 3.4 3 0 0 3 3 3 0 SlyX Uds1 PF15456.6 ORY72582.1 - 0.24 11.6 3.2 9.7 6.4 0.6 2.6 2 1 0 2 2 2 0 Up-regulated During Septation 7TM_GPCR_Srt PF10321.9 ORY72582.1 - 2.5 7.0 13.2 0.27 10.1 2.0 2.5 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srt Paf67 PF10255.9 ORY72583.1 - 1.8e-146 488.3 0.0 2.3e-146 487.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 ORY72583.1 - 0.0002 21.2 5.0 0.0065 16.5 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY72583.1 - 0.0065 16.7 1.6 4.2 7.7 0.0 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY72583.1 - 0.01 15.6 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY72583.1 - 0.11 13.1 0.1 0.11 13.1 0.1 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY72583.1 - 1.9 9.3 4.1 3.2 8.6 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SMG1 PF15785.5 ORY72584.1 - 0.045 12.1 0.2 0.057 11.8 0.2 1.0 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 UBN_AB PF14075.6 ORY72584.1 - 0.055 13.2 2.2 0.066 12.9 2.2 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain OAD_gamma PF04277.13 ORY72584.1 - 1 10.0 4.0 4.7 7.9 4.1 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3886 PF13025.6 ORY72584.1 - 8.5 6.7 9.9 0.14 12.4 2.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) PLA2_B PF01735.18 ORY72587.1 - 2.5e-111 372.5 0.1 3.1e-111 372.2 0.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Patatin PF01734.22 ORY72587.1 - 0.0033 17.6 6.5 0.0033 17.6 6.5 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase Mucin PF01456.17 ORY72587.1 - 1.1 9.2 14.9 4.2 7.3 14.9 2.0 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 ORY72587.1 - 9.1 6.7 10.7 1.7 9.1 6.0 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PLA2_B PF01735.18 ORY72588.1 - 5.4e-102 341.7 0.0 7.2e-102 341.3 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain MRP-S33 PF08293.11 ORY72589.1 - 3.3e-27 94.5 0.1 4e-27 94.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 GATase_6 PF13522.6 ORY72590.1 - 3.5e-13 49.9 0.0 7.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ORY72590.1 - 2.1e-10 40.4 0.2 3.7e-10 39.6 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.6 ORY72590.1 - 3.3e-10 40.0 0.0 6.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY72590.1 - 0.00031 19.7 0.0 0.0015 17.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferases class-II cwf18 PF08315.12 ORY72591.1 - 2e-34 119.2 14.4 2.4e-34 118.9 14.4 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor RHH_3 PF12651.7 ORY72591.1 - 0.052 13.5 0.4 0.11 12.5 0.4 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain Npa1 PF11707.8 ORY72591.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DUF1640 PF07798.11 ORY72591.1 - 0.36 10.9 4.8 0.42 10.6 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TAFII55_N PF04658.13 ORY72592.1 - 1.8e-46 157.8 0.1 1.8e-46 157.8 0.1 1.9 2 0 0 2 2 2 1 TAFII55 protein conserved region CHDCT2 PF08074.11 ORY72592.1 - 0.19 11.9 2.1 0.44 10.7 2.1 1.5 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain MA3 PF02847.17 ORY72593.1 - 1.3e-28 99.3 0.3 2.2e-28 98.5 0.3 1.4 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 ORY72593.1 - 2.6e-15 56.7 1.8 3.5e-15 56.2 0.2 2.0 2 0 0 2 2 2 1 MIF4G domain Glyco_transf_21 PF13506.6 ORY72594.1 - 8.3e-27 93.8 0.1 3.5e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORY72594.1 - 1e-13 51.7 0.0 1.4e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY72594.1 - 0.00063 19.7 0.2 0.00063 19.7 0.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 zf-C2H2 PF00096.26 ORY72595.1 - 6.6e-12 45.2 5.3 0.00012 22.4 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY72595.1 - 5e-09 36.2 1.4 0.00094 19.5 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY72595.1 - 1.7e-06 28.3 4.7 0.043 14.7 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY72595.1 - 0.067 13.2 0.6 8.5 6.5 0.0 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY72595.1 - 0.21 11.9 0.1 24 5.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DEAD PF00270.29 ORY72598.1 - 4.5e-33 114.5 0.0 1e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY72598.1 - 1.9e-27 95.8 0.0 1.1e-26 93.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY72598.1 - 3.1e-05 24.0 0.0 8.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY72598.1 - 0.029 14.7 0.7 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Hydantoinase_A PF01968.18 ORY72599.1 - 2.5e-96 322.4 0.7 4.7e-96 321.5 0.7 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY72599.1 - 7.8e-56 188.6 1.8 6e-53 179.2 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region AMO PF02461.16 ORY72599.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase MCM PF00493.23 ORY72600.1 - 1.1e-104 348.5 0.0 2.7e-104 347.2 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 ORY72600.1 - 2.7e-31 108.0 1.6 4.7e-31 107.3 1.6 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 ORY72600.1 - 1.4e-19 70.6 3.7 3.7e-19 69.2 3.7 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 ORY72600.1 - 6.3e-17 61.8 0.3 1.7e-16 60.4 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 ORY72600.1 - 3.1e-07 30.0 0.0 2.7e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY72600.1 - 1.2e-06 28.5 0.0 3.5e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY72600.1 - 0.0076 16.1 0.0 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 ORY72600.1 - 0.042 14.5 4.1 0.05 14.2 0.2 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 ORY72600.1 - 0.1 12.3 0.1 0.79 9.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain F-box-like PF12937.7 ORY72601.1 - 0.031 14.2 1.5 0.055 13.4 0.2 2.1 2 0 0 2 2 2 0 F-box-like HARE-HTH PF05066.13 ORY72602.1 - 0.035 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain HECT PF00632.25 ORY72603.1 - 3.1e-94 315.9 0.1 4e-94 315.5 0.1 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORY72603.1 - 2.3e-35 120.3 15.2 1.2e-12 47.7 1.9 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 ORY72603.1 - 4.2e-21 75.2 0.2 1.2e-20 73.7 0.2 1.8 1 0 0 1 1 1 1 C2 domain Glyco_transf_17 PF04724.13 ORY72604.1 - 6.1e-118 393.9 0.0 7e-118 393.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 SCAMP PF04144.13 ORY72605.1 - 4.2e-50 170.4 7.0 5.2e-50 170.2 7.0 1.1 1 0 0 1 1 1 1 SCAMP family F-box-like PF12937.7 ORY72606.1 - 2.6e-06 27.2 0.1 6.7e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like OGG_N PF07934.12 ORY72607.1 - 6e-24 84.5 0.0 3.5e-23 82.0 0.0 2.0 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 ORY72607.1 - 9.1e-09 35.7 0.0 2.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Nucleoporin_C PF03177.14 ORY72608.1 - 5.5e-91 306.1 5.4 7e-91 305.8 5.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 ORY72608.1 - 2.4e-20 72.7 0.0 3.9e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like UFD1 PF03152.14 ORY72609.1 - 4.7e-63 211.7 0.0 6.1e-63 211.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 ORY72609.1 - 0.0038 17.0 0.2 0.66 9.8 0.0 2.8 2 1 1 3 3 3 2 Cell division protein 48 (CDC48), domain 2 AMP-binding PF00501.28 ORY72610.1 - 3.4e-42 144.5 0.0 4.7e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY72610.1 - 9.8e-06 26.5 0.0 0.00018 22.4 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ndc1_Nup PF09531.10 ORY72611.1 - 6e-107 358.8 7.8 6.9e-107 358.6 7.8 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Galactosyl_T PF01762.21 ORY72612.1 - 2.1e-10 40.8 1.3 8.9e-08 32.2 0.1 3.0 2 1 1 3 3 3 2 Galactosyltransferase Haspin_kinase PF12330.8 ORY72718.1 - 2.2e-58 198.0 0.0 3.5e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain TFIIA PF03153.13 ORY72718.1 - 0.086 12.8 16.4 0.17 11.9 16.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ESCRT-II PF05871.12 ORY72719.1 - 5.1e-48 162.9 0.2 6.5e-48 162.5 0.2 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Aconitase PF00330.20 ORY72720.1 - 2.2e-150 501.7 0.0 2.9e-150 501.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY72720.1 - 2.4e-43 147.6 0.0 4.3e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Bac_luciferase PF00296.20 ORY72721.1 - 3.9e-54 184.2 1.4 6.3e-54 183.5 1.4 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.20 ORY72722.1 - 2.4e-52 178.3 0.8 4.8e-52 177.3 0.8 1.4 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_transf_41 PF13844.6 ORY72723.1 - 3.1e-87 293.0 12.9 5.5e-49 166.9 0.1 5.0 4 1 0 4 4 4 3 Glycosyl transferase family 41 TPR_1 PF00515.28 ORY72723.1 - 5.3e-20 70.3 8.1 5.7e-05 22.8 0.0 6.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY72723.1 - 1.1e-16 60.3 5.3 6.4e-05 22.6 0.0 6.8 4 2 3 7 7 7 4 TPR repeat TPR_2 PF07719.17 ORY72723.1 - 1.6e-15 55.8 5.2 0.11 12.7 0.0 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY72723.1 - 3.8e-15 54.8 0.3 0.00078 19.5 0.0 5.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY72723.1 - 1.6e-13 50.0 3.9 0.00051 20.2 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY72723.1 - 1.1e-10 41.6 1.1 0.1 12.9 0.0 5.2 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY72723.1 - 1.6e-09 37.8 0.9 0.06 14.2 0.0 6.4 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY72723.1 - 2.1e-09 37.0 7.9 0.036 14.0 0.0 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY72723.1 - 2.4e-08 33.4 0.1 1.7 8.9 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY72723.1 - 4.8e-08 33.4 0.1 0.0059 17.1 0.0 5.1 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY72723.1 - 0.00014 21.9 0.4 0.0037 17.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY72723.1 - 0.00018 22.0 0.3 0.41 11.4 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Secretin_N PF03958.17 ORY72723.1 - 0.76 10.2 5.8 0.12 12.8 0.5 2.6 2 0 0 2 2 1 0 Bacterial type II/III secretion system short domain Pkinase PF00069.25 ORY72724.1 - 2.1e-74 250.2 0.0 3e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY72724.1 - 7.4e-37 127.0 0.0 1e-36 126.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 ORY72724.1 - 3.1e-19 69.5 0.1 2.1e-17 63.7 0.1 2.7 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 ORY72724.1 - 1.2e-08 34.7 0.0 2.3e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY72724.1 - 0.0093 14.9 0.1 0.016 14.2 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 ORY72724.1 - 0.041 12.7 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 ORY72724.1 - 0.097 12.6 0.2 0.37 10.7 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY72724.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGEF67_u1 PF16615.5 ORY72726.1 - 8.2 7.0 10.2 6.8 7.3 2.2 3.1 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 Pyr_redox_2 PF07992.14 ORY72727.1 - 4.2e-08 32.8 0.0 2.7e-05 23.6 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY72727.1 - 0.0051 17.0 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY72727.1 - 0.015 15.3 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORY72727.1 - 0.024 15.2 0.1 2.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY72727.1 - 0.038 13.3 0.4 1.9 7.7 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY72727.1 - 0.038 12.7 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 ORY72727.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 ORY72727.1 - 0.47 9.5 3.9 0.73 8.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain PigN PF04987.14 ORY72728.1 - 3.2e-124 415.3 30.4 4e-124 415.0 30.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 ORY72728.1 - 1e-10 41.8 2.8 1.7e-10 41.1 0.9 2.0 2 1 1 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY72728.1 - 7.3e-07 28.9 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 ORY72728.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sld7_C PF18596.1 ORY72729.1 - 1.4e-07 31.6 0.0 2.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain BTB PF00651.31 ORY72730.1 - 2.2e-07 31.1 0.0 5.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Efg1 PF10153.9 ORY72731.1 - 1.5e-29 102.7 10.4 1.5e-29 102.7 10.4 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 DUF592 PF04574.13 ORY72731.1 - 0.18 11.6 1.3 0.31 10.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) MFS_1 PF07690.16 ORY72732.1 - 7.2e-25 87.6 37.0 7.2e-25 87.6 37.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Kinocilin PF15033.6 ORY72732.1 - 0.14 11.8 0.1 0.14 11.8 0.1 3.4 3 1 0 3 3 3 0 Kinocilin protein Acyltransferase PF01553.21 ORY72733.1 - 0.0058 16.2 0.0 0.022 14.4 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase DUF2839 PF10999.8 ORY72734.1 - 0.39 11.1 2.5 2.6 8.5 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Plasmid_RAQPRD PF09686.10 ORY72735.1 - 0.035 14.3 1.2 0.44 10.8 0.1 2.8 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Nup54 PF13874.6 ORY72735.1 - 0.035 14.2 0.4 0.073 13.2 0.4 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 SOAR PF16533.5 ORY72735.1 - 0.044 13.8 0.8 0.13 12.2 0.2 2.1 2 0 0 2 2 2 0 STIM1 Orai1-activating region FlaC_arch PF05377.11 ORY72735.1 - 0.044 14.2 5.0 0.11 12.9 0.8 3.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) OMPdecase PF00215.24 ORY72735.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Laminin_II PF06009.12 ORY72735.1 - 0.077 13.0 3.0 0.11 12.5 1.6 1.9 2 0 0 2 2 2 0 Laminin Domain II DUF812 PF05667.11 ORY72735.1 - 0.099 11.5 1.3 0.15 10.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) NPV_P10 PF05531.12 ORY72735.1 - 0.27 11.7 2.7 1.5 9.4 0.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 ORY72736.1 - 1.5e-52 178.6 0.0 1.3e-51 175.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY72736.1 - 5.6e-26 91.4 0.0 9e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Atg14 PF10186.9 ORY72736.1 - 0.31 10.1 4.7 0.47 9.5 4.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup192 PF11894.8 ORY72737.1 - 1.7e-287 957.1 0.0 2.1e-287 956.8 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 ORY72737.1 - 0.21 9.4 0.0 0.53 8.1 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 Cgr1 PF03879.14 ORY72738.1 - 3.2e-23 82.1 28.8 3.9e-23 81.9 28.8 1.0 1 0 0 1 1 1 1 Cgr1 family Atrophin-1 PF03154.15 ORY72738.1 - 0.76 8.0 9.6 0.73 8.0 9.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family SOG2 PF10428.9 ORY72739.1 - 0.029 13.6 37.6 0.0083 15.4 34.1 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein ODV-E18 PF10717.9 ORY72739.1 - 0.036 13.9 0.7 0.036 13.9 0.7 4.0 2 1 1 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 SpoIIIAH PF12685.7 ORY72739.1 - 0.072 12.9 12.6 0.056 13.3 10.6 1.8 2 0 0 2 2 2 0 SpoIIIAH-like protein Syntaxin PF00804.25 ORY72739.1 - 0.08 12.6 1.1 0.091 12.4 0.1 1.6 2 0 0 2 2 2 0 Syntaxin SID-1_RNA_chan PF13965.6 ORY72739.1 - 0.21 10.0 1.1 0.3 9.4 1.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FeoB_associated PF12669.7 ORY72739.1 - 0.25 11.8 0.2 0.52 10.7 0.2 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Otopetrin PF03189.13 ORY72739.1 - 0.3 9.8 0.0 0.3 9.8 0.0 2.1 2 0 0 2 2 2 0 Otopetrin Syntaxin-18_N PF10496.9 ORY72739.1 - 0.68 10.2 0.0 0.68 10.2 0.0 3.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus FAM70 PF14967.6 ORY72739.1 - 1.3 8.5 11.6 2.3 7.6 11.6 1.4 1 0 0 1 1 1 0 FAM70 protein DUF1242 PF06842.12 ORY72742.1 - 2.1e-18 65.8 1.0 2.8e-18 65.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) WD40 PF00400.32 ORY72743.1 - 1.4e-12 47.9 1.2 0.00063 20.5 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat YCII PF03795.14 ORY72745.1 - 0.044 14.2 0.0 0.058 13.8 0.0 1.2 1 0 0 1 1 1 0 YCII-related domain zf-MYND PF01753.18 ORY72746.1 - 1.8e-08 34.3 13.0 4.6e-08 33.0 13.0 1.8 1 0 0 1 1 1 1 MYND finger SelB-wing_2 PF09106.11 ORY72746.1 - 0.097 12.9 0.7 0.43 10.8 0.1 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix zf-C6H2 PF15801.5 ORY72746.1 - 0.46 10.8 8.3 0.48 10.8 6.8 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding RQC PF09382.10 ORY72747.1 - 5.3e-25 87.4 0.1 1e-24 86.5 0.1 1.4 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 ORY72747.1 - 4.6e-19 68.8 0.0 9.7e-17 61.3 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 ORY72747.1 - 4.2e-18 65.7 0.0 8.1e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 ORY72747.1 - 3.7e-16 59.6 3.9 9.3e-16 58.3 3.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 ORY72747.1 - 7.8e-06 25.8 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Mito_carr PF00153.27 ORY72748.1 - 1.7e-69 229.8 0.4 7e-24 83.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 ORY72748.1 - 7.4e-20 71.2 0.6 3.7e-07 30.5 0.0 4.9 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY72748.1 - 3.4e-18 64.0 1.6 4.7e-06 26.1 0.0 6.4 7 0 0 7 7 7 2 EF-hand domain EF-hand_1 PF00036.32 ORY72748.1 - 3.2e-17 60.7 6.3 2.8e-05 23.4 0.0 6.0 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 ORY72748.1 - 1.4e-13 50.4 2.6 0.001 18.8 2.2 4.9 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY72748.1 - 4.5e-10 38.6 1.9 0.00099 18.5 2.8 4.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 ORY72748.1 - 0.00023 21.4 0.0 0.29 11.5 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.13 ORY72748.1 - 0.07 13.0 0.1 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 Caleosin related protein Antimicrobial_8 PF08103.11 ORY72748.1 - 0.19 11.9 0.1 0.65 10.2 0.1 2.0 1 0 0 1 1 1 0 Uperin family Aldedh PF00171.22 ORY72749.1 - 3e-122 408.5 0.0 3.7e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY72749.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Vfa1 PF08432.10 ORY72750.1 - 0.5 10.7 7.9 0.66 10.3 7.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2524 PF10732.9 ORY72750.1 - 4.2 7.7 7.8 2 8.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) BTB PF00651.31 ORY72751.1 - 2.2e-06 27.8 0.0 4.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DnaJ-X PF14308.6 ORY72752.1 - 2.5e-41 141.4 7.7 4.3e-41 140.7 0.4 2.1 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.31 ORY72752.1 - 2.8e-23 81.8 1.1 6.2e-23 80.7 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain PEX11 PF05648.14 ORY72752.1 - 0.16 11.4 1.7 0.74 9.2 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) RNA_polI_A34 PF08208.11 ORY72752.1 - 0.72 9.9 13.1 0.15 12.2 9.0 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 HPP PF04982.13 ORY72754.1 - 1.3e-36 125.5 9.1 1.4e-36 125.3 7.4 1.8 2 0 0 2 2 2 1 HPP family MreD PF04093.12 ORY72754.1 - 0.41 10.7 4.0 0.16 12.0 1.4 1.6 2 0 0 2 2 2 0 rod shape-determining protein MreD PLDc PF00614.22 ORY72756.1 - 8.6e-18 63.7 0.3 1.2e-09 38.0 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORY72756.1 - 5.7e-14 52.1 0.1 2.5e-06 27.4 0.0 3.3 3 0 0 3 3 3 3 PLD-like domain BTB PF00651.31 ORY72757.1 - 4.4e-07 30.1 0.0 8.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 ORY72757.1 - 0.08 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Pkinase PF00069.25 ORY72758.1 - 5.2e-71 239.1 0.0 5.9e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY72758.1 - 1.4e-59 201.5 0.0 1.7e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY72758.1 - 0.00035 19.5 0.0 0.00041 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 ORY72758.1 - 0.00041 19.9 0.1 0.00059 19.4 0.1 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 ORY72758.1 - 0.00066 19.3 0.1 0.00087 18.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 ORY72758.1 - 0.011 15.0 0.0 0.09 12.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.11 ORY72758.1 - 0.015 14.4 0.2 0.024 13.7 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORY72758.1 - 0.087 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cys_Met_Meta_PP PF01053.20 ORY72759.1 - 2e-125 418.3 0.0 2.2e-125 418.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ORY72759.1 - 3e-11 43.2 0.1 6.8e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 ORY72759.1 - 6e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY72759.1 - 3.3e-05 23.0 0.1 5.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY72759.1 - 0.0011 18.3 0.0 0.0025 17.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Peptidase_S49_N PF08496.10 ORY72759.1 - 0.095 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Met_gamma_lyase PF06838.11 ORY72759.1 - 0.26 9.7 1.1 1.7 7.1 0.9 2.3 2 1 0 2 2 2 0 Methionine gamma-lyase F-box PF00646.33 ORY72760.1 - 0.00036 20.3 0.4 0.0008 19.2 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 ORY72760.1 - 0.00043 19.8 0.2 0.0014 18.2 0.0 1.9 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 ORY72760.1 - 0.0033 17.3 0.4 0.0083 16.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like adh_short PF00106.25 ORY72761.1 - 7e-35 120.3 0.0 1.3e-34 119.4 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY72761.1 - 1.9e-32 112.7 0.0 3.8e-32 111.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY72761.1 - 5.5e-05 23.2 0.1 9.4e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 KR domain V_ATPase_prox PF18274.1 ORY72761.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe Epimerase PF01370.21 ORY72761.1 - 0.11 11.9 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ORY72761.1 - 0.13 11.5 0.1 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 ORY72761.1 - 0.24 10.8 0.1 0.39 10.1 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Met_10 PF02475.16 ORY72763.1 - 2.7e-62 210.0 0.0 3.5e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ORY72763.1 - 0.0054 16.0 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.10 ORY72763.1 - 0.028 14.0 0.0 0.066 12.8 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 ORY72763.1 - 0.037 13.7 0.1 0.6 9.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PrmA PF06325.13 ORY72763.1 - 0.051 13.0 0.1 0.076 12.4 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TAFII28 PF04719.14 ORY72765.1 - 4.5e-29 100.4 0.0 6.4e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF444 PF04285.12 ORY72765.1 - 0.31 10.1 3.2 0.38 9.8 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) SLR1-BP PF07333.12 ORY72766.1 - 6.3 7.3 21.3 4.4 7.8 5.1 3.5 2 1 1 3 3 3 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Vanabin-2 PF11437.8 ORY72766.1 - 7.1 6.9 23.0 4.6 7.5 12.0 2.7 1 1 2 3 3 3 0 Vanadium-binding protein 2 RibD_C PF01872.17 ORY72767.1 - 7.2e-38 130.4 0.0 8.7e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Septin PF00735.18 ORY72769.1 - 1.6e-110 368.8 0.1 2.2e-110 368.4 0.1 1.1 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 ORY72769.1 - 5.2e-09 36.2 0.1 6.1e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY72769.1 - 3.7e-08 33.4 0.0 8.3e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY72769.1 - 4e-06 26.5 0.6 0.00025 20.7 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 ORY72769.1 - 0.00015 21.4 0.5 0.00042 19.9 0.5 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY72769.1 - 0.00074 19.7 0.1 0.0017 18.5 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY72769.1 - 0.00091 19.6 0.6 0.0026 18.2 0.6 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY72769.1 - 0.00099 19.4 0.6 0.004 17.4 0.1 2.3 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 ORY72769.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_7 PF12775.7 ORY72769.1 - 0.0041 16.6 0.2 0.0078 15.7 0.2 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 ORY72769.1 - 0.0043 17.3 1.2 0.0075 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 ORY72769.1 - 0.011 15.4 1.2 0.43 10.3 0.1 2.6 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORY72769.1 - 0.013 16.0 0.1 0.041 14.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Bac_DnaA PF00308.18 ORY72769.1 - 0.033 14.0 3.5 0.91 9.3 0.6 2.9 2 1 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.22 ORY72769.1 - 0.042 13.0 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain FeoB_N PF02421.18 ORY72769.1 - 0.054 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 ORY72769.1 - 0.057 13.1 1.1 0.17 11.5 1.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY72769.1 - 0.062 13.2 0.6 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY72769.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 ORY72769.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.14 ORY72769.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FOXP-CC PF16159.5 ORY72769.1 - 0.072 13.7 0.8 0.21 12.2 0.8 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain Pox_A32 PF04665.12 ORY72769.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.17 ORY72769.1 - 0.13 12.0 0.4 22 4.7 0.1 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 ORY72769.1 - 0.79 9.8 7.1 5.9 6.9 0.1 3.0 2 1 1 3 3 3 0 Dynamin family adh_short_C2 PF13561.6 ORY72770.1 - 4.7e-49 167.1 0.7 5.4e-49 166.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY72770.1 - 6.4e-42 143.2 3.2 8.2e-42 142.9 3.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY72770.1 - 1.3e-10 41.5 1.5 2.3e-10 40.7 1.5 1.4 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY72770.1 - 0.0003 20.7 0.1 0.00047 20.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 ORY72770.1 - 0.0073 15.8 0.6 0.023 14.1 0.6 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Transketolase_C PF02780.20 ORY72770.1 - 0.036 13.9 0.8 8.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Transketolase, C-terminal domain Rad21_Rec8_N PF04825.13 ORY72771.1 - 1.4e-34 118.6 0.0 2.5e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORY72771.1 - 1.3e-12 46.8 2.0 1.7e-12 46.5 0.3 2.1 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein Pil1 PF13805.6 ORY72772.1 - 2.9e-17 63.1 2.0 6.4e-17 61.9 2.0 1.6 1 0 0 1 1 1 1 Eisosome component PIL1 Metal_resist PF13801.6 ORY72772.1 - 1 9.6 13.6 3.2 8.0 0.8 3.8 3 0 0 3 3 3 0 Heavy-metal resistance DUF4570 PF15134.6 ORY72774.1 - 0.0056 16.7 1.4 0.0098 15.9 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) zf-C2H2 PF00096.26 ORY72775.1 - 0.00041 20.6 9.8 0.021 15.3 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 ORY72775.1 - 0.00065 19.9 9.6 0.031 14.4 0.1 2.5 3 0 0 3 3 3 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 ORY72775.1 - 0.051 14.0 6.3 2.3 8.8 1.3 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY72775.1 - 0.055 13.8 0.1 0.22 11.9 0.1 2.1 1 1 0 1 1 1 0 C2H2-type zinc ribbon DUF4106 PF13388.6 ORY72775.1 - 1.8 7.7 8.7 2.8 7.1 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) zf-C2H2_4 PF13894.6 ORY72775.1 - 4.2 8.5 16.1 3.2 8.9 1.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Mg_trans_NIPA PF05653.14 ORY72881.1 - 1.3e-38 132.8 4.8 2.5e-38 131.9 4.3 1.6 2 0 0 2 2 2 1 Magnesium transporter NIPA Pkinase_fungal PF17667.1 ORY72881.1 - 0.00012 21.0 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase NrfD_2 PF14589.6 ORY72881.1 - 0.032 14.2 2.9 0.056 13.4 2.9 1.3 1 0 0 1 1 1 0 Polysulfide reductase EamA PF00892.20 ORY72881.1 - 0.67 10.1 17.6 0.54 10.4 0.2 2.7 2 1 0 2 2 2 0 EamA-like transporter family Pkinase_fungal PF17667.1 ORY72882.1 - 1.3e-14 53.8 0.9 1.9e-14 53.3 0.2 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY72882.1 - 3.1e-06 27.3 0.5 6.5e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 ORY72882.1 - 0.00041 19.8 0.0 0.00065 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 ORY72882.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 ORY72882.1 - 0.027 14.0 0.0 0.087 12.4 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF89 PF01937.19 ORY72884.1 - 1.1e-108 363.4 0.0 1.2e-108 363.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 UBX PF00789.20 ORY72885.1 - 1.9e-10 40.8 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 ORY72885.1 - 1.9e-06 27.7 0.0 6.7e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain zf-LYAR PF08790.11 ORY72885.1 - 0.033 14.1 1.1 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 ORY72885.1 - 0.047 14.0 0.2 0.14 12.5 0.1 1.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Peptidase_M55 PF04951.13 ORY72885.1 - 0.88 8.9 6.0 1.5 8.1 6.0 1.3 1 0 0 1 1 1 0 D-aminopeptidase CCDC66 PF15236.6 ORY72885.1 - 0.97 9.3 28.1 1.7 8.4 28.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Borrelia_P83 PF05262.11 ORY72885.1 - 0.98 7.8 16.3 1.1 7.6 16.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC2_membrane PF01061.24 ORY72886.1 - 2.5e-74 249.2 43.3 2.4e-38 131.7 18.7 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORY72886.1 - 1.4e-32 113.1 0.0 6.4e-15 55.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY72886.1 - 2.3e-26 91.5 0.6 6.5e-18 64.4 0.0 3.9 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY72886.1 - 8.6e-09 35.9 0.1 2.4e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 ORY72886.1 - 1.2e-06 28.8 0.2 0.0078 16.4 0.1 3.1 4 0 0 4 4 2 2 AAA domain ABC2_membrane_3 PF12698.7 ORY72886.1 - 1.2e-05 24.6 39.2 0.00025 20.3 7.8 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 ORY72886.1 - 1.6e-05 25.3 2.9 0.0031 17.9 0.1 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 ORY72886.1 - 4.5e-05 23.4 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY72886.1 - 0.00011 21.8 0.2 0.007 16.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY72886.1 - 0.00024 20.7 0.1 0.045 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY72886.1 - 0.00037 20.4 0.2 0.001 19.0 0.0 1.9 2 0 0 2 2 1 1 RsgA GTPase SMC_N PF02463.19 ORY72886.1 - 0.0028 17.1 0.0 0.71 9.3 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ORY72886.1 - 0.0051 16.6 0.6 0.24 11.1 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY72886.1 - 0.0059 16.9 0.4 0.66 10.2 0.2 3.0 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 ORY72886.1 - 0.0078 15.8 1.3 0.72 9.4 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 ORY72886.1 - 0.018 14.9 0.7 6.4 6.7 0.2 2.6 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 ORY72886.1 - 0.019 14.3 0.3 1.8 7.9 0.0 2.6 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_28 PF13521.6 ORY72886.1 - 0.03 14.6 0.1 0.35 11.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY72886.1 - 0.033 14.7 0.0 2.2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY72886.1 - 0.04 14.4 0.0 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY72886.1 - 0.044 13.5 0.0 7 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY72886.1 - 0.048 12.9 0.1 3.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 ORY72886.1 - 0.059 13.8 0.1 18 5.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 ORY72886.1 - 0.16 11.6 0.0 0.88 9.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 ORY72886.1 - 0.32 11.3 0.8 14 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain HEM4 PF02602.15 ORY72888.1 - 1.3e-19 70.5 0.0 7.7e-19 68.0 0.0 2.1 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Mito_carr PF00153.27 ORY72889.1 - 2e-62 207.1 3.7 1.5e-21 76.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 ORY72890.1 - 0.0037 17.1 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 ORY72890.1 - 0.087 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 PRANC domain Sec31 PF11549.8 ORY72890.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein transport protein SEC31 Cu_amine_oxid PF01179.20 ORY72891.1 - 7.3e-35 120.7 0.0 8.1e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Pkinase_fungal PF17667.1 ORY72892.1 - 6.3e-18 64.7 0.0 2.3e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 ORY72892.1 - 2.2e-05 24.5 0.4 5.4e-05 23.2 0.4 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 ORY72892.1 - 0.028 13.8 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain NBP1 PF08537.10 ORY72893.1 - 0.1 12.0 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 zf-primase PF09329.11 ORY72894.1 - 3.2e-12 46.0 4.0 5.8e-12 45.2 4.0 1.4 1 0 0 1 1 1 1 Primase zinc finger SUI1 PF01253.22 ORY72895.1 - 1.6e-11 44.5 0.6 1.6e-09 38.1 0.0 2.5 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 ORY72895.1 - 8.7e-11 42.4 0.0 1.3e-09 38.6 0.0 2.7 3 0 0 3 3 3 1 Pre-PUA-like domain SWIB PF02201.18 ORY72895.1 - 0.019 14.8 0.1 0.073 13.0 0.0 2.0 2 0 0 2 2 2 0 SWIB/MDM2 domain Vps35 PF03635.17 ORY72896.1 - 0 1024.2 0.0 0 1024.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Dynein_AAA_lid PF17852.1 ORY72896.1 - 0.089 12.9 0.0 0.69 10.0 0.0 2.3 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain DUF5029 PF16432.5 ORY72896.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5029) DUF1295 PF06966.12 ORY72897.1 - 4.8e-55 186.6 0.8 6.9e-55 186.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ORY72897.1 - 5.7e-05 23.5 0.0 5.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 ORY72897.1 - 0.00016 21.7 1.9 0.00021 21.3 0.0 2.0 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ORY72897.1 - 0.0003 21.1 0.0 0.00092 19.6 0.0 1.9 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Cu_amine_oxid PF01179.20 ORY72898.1 - 7.7e-22 77.8 0.1 9.3e-22 77.5 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain PP28 PF10252.9 ORY72899.1 - 1.6e-24 86.1 20.3 1.6e-24 86.1 20.3 2.8 2 1 0 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Fungal_trans_2 PF11951.8 ORY72901.1 - 8.4e-17 61.0 0.2 6.4e-16 58.1 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY72901.1 - 0.006 16.7 9.1 0.0092 16.1 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 ORY72902.1 - 4.5e-22 78.2 0.1 1.7e-21 76.3 0.1 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY72902.1 - 1.6e-20 73.6 0.0 1.1e-16 60.9 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY72902.1 - 1.5e-16 60.5 0.0 1.2e-06 28.0 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY72902.1 - 5.1e-09 35.7 0.1 1.5e-05 24.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 ORY72902.1 - 2.2e-08 34.5 0.5 0.018 15.6 0.0 4.1 5 0 0 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY72902.1 - 1.1e-06 28.2 0.1 2.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 ORY72902.1 - 3.6e-06 26.8 0.1 0.015 14.9 0.0 3.2 2 1 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY72902.1 - 5.4e-05 23.3 0.0 0.00042 20.5 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY72902.1 - 0.00033 19.5 0.5 0.0078 15.0 0.0 2.6 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_9 PF13454.6 ORY72902.1 - 0.00094 19.2 0.1 1.3 9.0 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY72902.1 - 0.0021 17.2 0.2 0.036 13.1 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 ORY72902.1 - 0.0052 17.2 0.0 1.6 9.2 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 ORY72902.1 - 0.0092 15.1 0.1 0.07 12.2 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 ORY72902.1 - 0.015 15.6 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 ORY72902.1 - 0.025 14.7 0.0 3.3 7.8 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ORY72902.1 - 0.029 13.8 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY72902.1 - 0.13 12.2 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 ORY72902.1 - 0.13 11.5 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY72902.1 - 0.15 11.2 1.7 4.8 6.2 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A IlvN PF07991.12 ORY72902.1 - 0.16 11.5 0.0 0.84 9.2 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GSu_C4xC__C2xCH PF09698.10 ORY72902.1 - 5.3 7.9 7.2 16 6.4 7.2 1.9 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) PS_Dcarbxylase PF02666.15 ORY72903.1 - 4.2e-54 183.2 0.0 5.8e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RINGv PF12906.7 ORY72904.1 - 4.1e-06 26.8 8.5 8e-06 25.9 8.5 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ORY72904.1 - 0.0014 18.9 7.2 0.0025 18.1 7.2 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 ORY72904.1 - 0.049 13.8 5.9 0.086 13.0 4.9 1.9 2 0 0 2 2 2 0 FANCL C-terminal domain DUF2457 PF10446.9 ORY72904.1 - 0.45 9.6 7.5 0.88 8.6 7.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Zn_ribbon_17 PF17120.5 ORY72904.1 - 1.6 8.4 5.1 3.3 7.4 5.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type WD40 PF00400.32 ORY72905.1 - 1.5e-11 44.7 2.3 3.2e-07 30.9 0.1 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY72905.1 - 2.3e-07 31.0 0.0 0.0058 16.9 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DASH_Spc19 PF08287.11 ORY72905.1 - 0.011 15.7 1.2 0.024 14.5 1.2 1.5 1 1 0 1 1 1 0 Spc19 Mem_trans PF03547.18 ORY72905.1 - 0.15 10.5 1.1 3 6.1 0.3 2.1 2 0 0 2 2 2 0 Membrane transport protein adh_short_C2 PF13561.6 ORY72907.1 - 1.6e-51 175.1 7.5 1.9e-41 142.2 6.7 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY72907.1 - 1.4e-43 148.7 5.0 1.7e-43 148.4 5.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY72907.1 - 6.2e-14 52.3 4.2 2.3e-13 50.5 4.2 1.8 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY72907.1 - 0.023 14.6 0.9 0.045 13.6 0.9 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pept_tRNA_hydro PF01195.19 ORY72908.1 - 9.8e-30 103.8 0.0 1.2e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase MFS_1 PF07690.16 ORY72909.1 - 6.3e-30 104.3 21.3 7.6e-30 104.0 21.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Copper-fist PF00649.18 ORY72910.1 - 1.3e-17 62.9 0.6 1.3e-17 62.9 0.6 1.6 2 0 0 2 2 2 1 Copper fist DNA binding domain Glyco_hydro_3_C PF01915.22 ORY72911.1 - 1.9e-64 217.4 0.0 1.6e-63 214.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY72911.1 - 5.7e-48 163.9 0.0 9.3e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY72911.1 - 4e-24 84.5 0.7 9.9e-24 83.2 0.7 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ORY72911.1 - 0.00025 20.9 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Arm-DNA-bind_3 PF13356.6 ORY72911.1 - 0.03 14.7 0.1 0.078 13.4 0.1 1.6 1 0 0 1 1 1 0 Arm DNA-binding domain NPCBM_assoc PF10633.9 ORY72911.1 - 0.067 13.5 0.5 0.19 12.0 0.5 1.8 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase adh_short_C2 PF13561.6 ORY72913.1 - 1.9e-52 178.1 6.3 4.5e-42 144.2 6.3 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY72913.1 - 1.2e-46 158.6 6.3 1.5e-46 158.3 6.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY72913.1 - 2.9e-14 53.4 3.3 1.3e-13 51.3 3.3 1.8 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY72913.1 - 0.003 17.4 0.8 0.03 14.2 0.6 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CbiG_N PF11760.8 ORY72913.1 - 0.078 13.0 0.2 0.078 13.0 0.2 2.2 2 1 1 3 3 3 0 Cobalamin synthesis G N-terminal Bacillus_PapR PF05968.11 ORY72913.1 - 0.14 12.1 1.9 2.9 7.8 0.4 2.7 2 0 0 2 2 2 0 Bacillus PapR protein DUF881 PF05949.12 ORY72913.1 - 0.73 9.7 4.0 0.21 11.5 0.9 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) RasGEF PF00617.19 ORY72914.1 - 6.9e-43 146.9 0.0 1.3e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY72914.1 - 2.5e-15 56.6 0.1 1.1e-14 54.5 0.2 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Sod_Fe_N PF00081.22 ORY72915.1 - 1.3e-30 105.7 0.5 2.5e-30 104.8 0.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 ORY72915.1 - 4.2e-29 100.7 0.0 8.5e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain DUF3584 PF12128.8 ORY72916.1 - 0.82 7.1 28.4 1.2 6.6 28.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 ORY72916.1 - 1.5 7.4 10.3 2.8 6.4 10.3 1.4 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 ORY72916.1 - 4.7 6.7 12.3 8.3 5.9 12.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMgT PF10270.9 ORY72917.1 - 1.2e-13 51.3 0.0 1.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Membrane magnesium transporter Saf_2TM PF18303.1 ORY72917.1 - 0.041 13.5 0.4 0.055 13.1 0.4 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DEAD PF00270.29 ORY72918.1 - 6.4e-25 87.9 0.0 1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 ORY72918.1 - 3.3e-21 75.8 2.2 1.2e-20 74.0 2.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 ORY72918.1 - 1.3e-13 51.2 0.0 1.3e-11 44.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.11 ORY72918.1 - 7e-07 29.7 0.2 1.5e-06 28.7 0.2 1.6 1 1 0 1 1 1 1 DNA replication factor CDT1 like ResIII PF04851.15 ORY72918.1 - 4.9e-06 26.6 0.0 8.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Eco57I PF07669.11 ORY72918.1 - 0.17 12.4 0.0 5.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Eco57I restriction-modification methylase Rft-1 PF04506.13 ORY72919.1 - 1.2e-116 390.5 0.0 1.7e-116 390.0 0.0 1.1 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 ORY72919.1 - 6.2e-07 28.9 0.3 1.5e-06 27.7 0.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 ORY72919.1 - 0.00059 19.3 1.7 0.00059 19.3 1.7 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein DUF374 PF04028.13 ORY72919.1 - 0.032 13.8 0.1 0.082 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Cu_amine_oxid PF01179.20 ORY72920.1 - 4e-108 362.0 0.4 5e-108 361.6 0.4 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 ORY72920.1 - 1.3e-23 82.5 0.9 2.6e-23 81.6 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 ORY72920.1 - 0.044 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain IBV_3B PF03622.13 ORY72920.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 IBV 3B protein Gpr1_Fun34_YaaH PF01184.19 ORY72921.1 - 2.4e-40 138.4 20.5 3e-40 138.0 20.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Myb_DNA-binding PF00249.31 ORY72924.1 - 0.00012 22.2 0.0 0.00038 20.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain DAHP_synth_1 PF00793.20 ORY72925.1 - 9e-90 300.3 0.0 1.1e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Sec31 PF11549.8 ORY72927.1 - 0.17 11.8 0.1 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein transport protein SEC31 UCH PF00443.29 ORY72928.1 - 6.2e-47 160.2 0.0 7.5e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY72928.1 - 9.7e-12 45.1 0.4 7.3e-10 38.9 0.4 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORY72928.1 - 8.6e-10 38.2 0.1 2.2e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 ORY72928.1 - 0.0028 18.0 0.4 0.01 16.2 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-like domain RPT PF13446.6 ORY72929.1 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 A repeated domain in UCH-protein CENP-F_leu_zip PF10473.9 ORY72929.1 - 0.0039 17.2 8.1 0.0039 17.2 8.1 4.2 4 0 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dad4 PF08650.10 ORY72929.1 - 0.29 11.1 3.2 12 6.0 1.2 3.0 2 1 0 2 2 2 0 DASH complex subunit Dad4 UPF0242 PF06785.11 ORY72929.1 - 7 6.7 23.7 3.4 7.7 9.4 3.3 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_C65 PF10275.9 ORY72930.1 - 2e-65 220.7 0.0 2.4e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain MauJ PF17419.2 ORY72930.1 - 0.14 11.6 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Mem_trans PF03547.18 ORY72931.1 - 4.5e-13 48.4 11.8 3.1e-07 29.1 0.9 2.4 2 1 0 2 2 2 2 Membrane transport protein RhoGEF PF00621.20 ORY72932.1 - 5e-26 92.0 0.0 2.2e-24 86.7 0.0 2.8 2 1 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 ORY72932.1 - 1.7e-19 69.7 3.3 2.8e-19 69.0 3.3 1.3 1 0 0 1 1 1 1 FYVE zinc finger PH_13 PF16652.5 ORY72932.1 - 1.1e-06 28.5 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH PF00169.29 ORY72932.1 - 0.00031 21.2 0.0 0.0012 19.3 0.0 2.1 2 1 0 2 2 2 1 PH domain FYVE_2 PF02318.16 ORY72932.1 - 0.11 12.7 3.1 0.27 11.5 3.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger DEAD PF00270.29 ORY72933.1 - 3.1e-37 128.0 0.0 6e-37 127.1 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY72933.1 - 1.3e-23 83.5 0.0 9e-23 80.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY72933.1 - 5.8e-09 36.2 0.0 1.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 ORY72933.1 - 0.027 14.4 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 ORY72933.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RTC PF01137.21 ORY72934.1 - 4.8e-36 124.0 0.0 6.1e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 ORY72934.1 - 1.3e-13 51.3 0.3 2.2e-13 50.6 0.3 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MFS_1 PF07690.16 ORY72935.1 - 4.9e-28 98.1 32.2 4.9e-28 98.1 32.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY72935.1 - 4e-08 32.6 7.2 4e-08 32.6 7.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter RSN1_7TM PF02714.15 ORY72937.1 - 1.6e-66 224.4 17.4 1.6e-66 224.4 17.4 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY72937.1 - 3.2e-42 143.9 3.5 3.2e-42 143.9 3.5 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY72937.1 - 5.9e-33 114.6 0.0 4.8e-32 111.6 0.0 2.0 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TMC PF07810.13 ORY72937.1 - 0.0021 18.6 1.1 0.0021 18.6 1.1 3.2 3 1 1 4 4 4 1 TMC domain WW PF00397.26 ORY72938.1 - 1.2e-10 41.2 2.1 3.3e-10 39.9 2.1 1.8 1 0 0 1 1 1 1 WW domain ALO PF04030.14 ORY72939.1 - 4e-39 135.0 0.1 6e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase WW PF00397.26 ORY72939.1 - 2.5e-05 24.3 8.1 7.6e-05 22.7 8.1 1.9 1 0 0 1 1 1 1 WW domain Med19 PF10278.9 ORY72939.1 - 0.14 12.0 14.9 0.15 12.0 14.0 1.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF2267 PF10025.9 ORY73052.1 - 0.052 13.8 0.7 0.052 13.8 0.7 2.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) HSP70 PF00012.20 ORY73053.1 - 0.23 9.6 0.1 14 3.7 0.0 2.1 2 0 0 2 2 2 0 Hsp70 protein zf-MYND PF01753.18 ORY73054.1 - 8.3e-09 35.4 15.6 8.3e-09 35.4 15.6 2.2 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 ORY73054.1 - 1.3 9.4 10.6 3.2 8.1 10.6 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HA2 PF04408.23 ORY73055.1 - 3.9e-24 85.0 0.1 7.6e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY73055.1 - 1.3e-14 54.3 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY73055.1 - 4.6e-13 49.5 0.0 9.5e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY73055.1 - 0.056 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase MOSP_C PF02722.15 ORY73056.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 2 0 0 2 2 2 0 Major Outer Sheath Protein C-terminal domain Epimerase PF01370.21 ORY73057.1 - 6e-51 173.2 0.0 7.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY73057.1 - 6e-17 62.0 0.0 2.2e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY73057.1 - 6.8e-05 22.1 0.2 0.0067 15.6 0.2 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY73057.1 - 0.00053 19.2 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY73057.1 - 0.0025 16.9 0.0 0.0045 16.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family LSM PF01423.22 ORY73058.1 - 1.7e-18 66.1 0.1 2.2e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain PCI PF01399.27 ORY73059.1 - 6.3e-14 52.4 0.0 2.3e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain SHE3 PF17078.5 ORY73060.1 - 0.13 12.0 0.2 0.19 11.4 0.2 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 La PF05383.17 ORY73061.1 - 2e-18 66.2 0.0 2.8e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 La domain Pkinase PF00069.25 ORY73062.1 - 8.2e-38 130.3 0.0 6.1e-37 127.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY73062.1 - 1.1e-21 77.3 0.0 1.9e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY73062.1 - 0.00031 19.7 0.1 0.00031 19.7 0.1 1.5 2 0 0 2 2 2 1 Fungal protein kinase DUF3395 PF11875.8 ORY73064.1 - 2.1e-45 154.4 0.1 3.3e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 ORY73064.1 - 7e-20 70.9 0.5 2e-19 69.5 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain Bac_surface_Ag PF01103.23 ORY73065.1 - 1.3e-38 133.3 0.1 2.1e-38 132.6 0.1 1.3 1 1 0 1 1 1 1 Surface antigen Clathrin PF00637.20 ORY73066.1 - 7.3e-204 667.9 32.8 2.3e-32 111.8 2.2 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 ORY73066.1 - 2.8e-35 118.9 0.0 4.7e-06 26.6 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 ORY73066.1 - 5.5e-33 112.7 0.7 2.5e-32 110.6 0.2 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 ORY73066.1 - 8.2e-13 47.5 0.6 2.2e-12 46.1 0.6 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 ORY73066.1 - 3.1e-06 26.5 4.0 0.089 11.8 0.2 4.5 4 1 0 4 4 4 2 Coatomer WD associated region TPR_1 PF00515.28 ORY73066.1 - 0.0018 18.0 3.7 12 5.9 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Vps39_1 PF10366.9 ORY73066.1 - 0.0031 17.8 9.2 1.4 9.3 0.1 5.6 6 1 0 6 6 6 2 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 ORY73066.1 - 0.038 14.1 10.8 52 4.3 0.2 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY73066.1 - 0.08 13.8 20.4 7.3 7.7 0.1 9.5 10 2 2 12 12 11 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY73066.1 - 0.14 12.3 13.7 0.41 10.8 0.2 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY73066.1 - 0.21 11.9 4.3 33 5.0 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Hexokinase_1 PF00349.21 ORY73067.1 - 0.12 12.2 0.0 7.8 6.3 0.0 2.9 4 0 0 4 4 4 0 Hexokinase Macoilin PF09726.9 ORY73068.1 - 0.033 12.8 9.7 0.048 12.2 9.7 1.1 1 0 0 1 1 1 0 Macoilin family Glycogen_syn PF05693.13 ORY73069.1 - 0 1113.8 0.0 0 1113.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 ORY73069.1 - 5.7e-07 29.2 0.0 0.0001 21.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY73069.1 - 1.7e-06 28.5 0.0 0.0014 19.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ORY73069.1 - 2.4e-05 24.1 0.1 6.3e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 ORY73069.1 - 0.00011 22.3 0.1 0.00019 21.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORY73069.1 - 0.00021 21.8 0.0 0.00059 20.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Peptidase_M24 PF00557.24 ORY73071.1 - 1.8e-44 152.0 0.0 2.5e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 ORY73071.1 - 6e-42 143.5 0.0 4.3e-40 137.4 0.0 3.2 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 ORY73071.1 - 5.3e-24 84.1 1.5 3e-22 78.4 0.5 2.9 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ORY73071.1 - 2e-15 57.6 0.0 1.5e-14 54.8 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain VASP_tetra PF08776.11 ORY73071.1 - 3.1 7.4 7.3 1 9.0 3.0 2.1 2 0 0 2 2 2 0 VASP tetramerisation domain HLH PF00010.26 ORY73072.1 - 2.3e-17 62.7 0.0 4.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Oxysterol_BP PF01237.18 ORY73073.1 - 6.3e-36 124.0 0.0 5.7e-34 117.6 0.0 2.8 1 1 0 1 1 1 1 Oxysterol-binding protein ParA PF10609.9 ORY73075.1 - 2.2e-78 263.1 0.0 3.5e-78 262.5 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY73075.1 - 5.5e-07 29.7 0.0 6.5e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY73075.1 - 0.00012 22.0 0.0 0.04 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ArsA_ATPase PF02374.15 ORY73075.1 - 0.00024 20.4 0.0 0.0039 16.4 0.0 2.3 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 ORY73075.1 - 0.00081 18.8 0.0 0.0063 15.8 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 ORY73075.1 - 0.014 15.0 0.2 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 ORY73075.1 - 0.055 12.9 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Desulfoferrod_N PF06397.12 ORY73075.1 - 0.092 12.4 0.6 0.21 11.2 0.6 1.5 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain UMP1 PF05348.11 ORY73076.1 - 3e-37 127.4 0.3 3.6e-37 127.2 0.3 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF5386 PF17360.2 ORY73076.1 - 0.058 13.3 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5386) eIF3g PF12353.8 ORY73078.1 - 6.9e-44 149.2 2.1 1.1e-43 148.6 2.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 ORY73078.1 - 8.7e-19 67.1 0.0 1.7e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY73078.1 - 0.0019 18.2 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 ORY73078.1 - 0.075 12.9 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF3602 PF12223.8 ORY73082.1 - 1.5e-09 38.3 11.0 1.9e-05 25.2 1.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Histone PF00125.24 ORY73083.1 - 4.3e-51 172.7 2.8 4.8e-51 172.5 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY73083.1 - 2.1e-05 24.8 0.0 3.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ORY73083.1 - 8.1e-05 23.2 1.1 9.5e-05 23.0 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 ORY73083.1 - 0.00013 22.0 0.5 0.0002 21.4 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ORY73083.1 - 0.0035 17.6 0.0 0.0068 16.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 ORY73083.1 - 0.025 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 ORY73083.1 - 0.026 14.6 0.1 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit HMG-CoA_red PF00368.18 ORY73084.1 - 3.2e-134 447.6 4.5 4.3e-134 447.2 4.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 ORY73084.1 - 4.7e-12 46.0 12.0 9.2e-09 35.3 0.3 2.9 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ORY73084.1 - 1.4e-07 30.0 1.1 3.5e-07 28.7 0.2 2.0 2 1 0 2 2 2 1 Patched family ResB PF05140.14 ORY73084.1 - 0.0016 17.3 0.1 0.0028 16.5 0.1 1.3 1 0 0 1 1 1 1 ResB-like family N36 PF11438.8 ORY73084.1 - 0.37 10.7 1.6 0.96 9.3 1.6 1.7 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) DUF3602 PF12223.8 ORY73085.1 - 5.6e-15 55.7 31.8 4e-08 33.7 9.1 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) PBP1_TM PF14812.6 ORY73085.1 - 4.2 7.8 8.5 0.92 9.9 2.6 2.3 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1152 PF06626.12 ORY73087.1 - 0.015 14.5 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) bZIP_2 PF07716.15 ORY73088.1 - 4.9e-07 29.7 8.8 1.3e-06 28.3 8.8 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY73088.1 - 4.2e-06 26.7 7.9 7.4e-06 26.0 7.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 ORY73088.1 - 0.12 12.9 3.9 0.22 12.1 3.9 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 ORY73089.1 - 1.5e-09 37.8 4.1 1.5e-09 37.8 4.1 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY73089.1 - 2.9e-06 27.2 5.0 2.9e-06 27.2 5.0 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY73089.1 - 0.00046 20.6 3.7 0.00046 20.6 3.7 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor Mod_r PF07200.13 ORY73089.1 - 0.89 9.6 5.0 0.53 10.4 0.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nnf1 PF03980.14 ORY73089.1 - 1.4 9.3 11.4 3.7 8.0 1.3 2.4 2 0 0 2 2 2 0 Nnf1 TolA_bind_tri PF16331.5 ORY73089.1 - 1.8 8.7 6.8 0.21 11.7 0.6 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation Cnn_1N PF07989.11 ORY73089.1 - 4.3 7.6 6.6 0.24 11.6 0.5 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Grg1 PF11034.8 ORY73090.1 - 4.1e-23 81.4 10.5 5.9e-23 80.9 10.5 1.2 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Peptidase_M35 PF02102.15 ORY73090.1 - 1.1 8.1 8.3 1.2 7.9 8.3 1.0 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family KH_1 PF00013.29 ORY73091.1 - 0.0002 21.1 0.6 0.0012 18.6 0.1 2.3 2 1 0 2 2 2 1 KH domain MIP PF00230.20 ORY73092.1 - 5.1e-51 173.6 8.0 7.3e-51 173.1 8.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein Lys_export PF03956.13 ORY73092.1 - 0.13 11.8 4.4 0.2 11.2 2.0 2.2 2 0 0 2 2 2 0 Lysine exporter LysO PHY PF00360.20 ORY73093.1 - 1.3e-27 96.3 0.0 3.2e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region Response_reg PF00072.24 ORY73093.1 - 1e-20 74.0 0.0 3.3e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ORY73093.1 - 3.5e-17 62.9 0.1 6.6e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_2 PF08446.11 ORY73093.1 - 1.2e-08 35.6 0.0 2.9e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 PAS fold GAF PF01590.26 ORY73093.1 - 2.5e-07 31.4 0.1 8.6e-07 29.7 0.1 2.0 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 ORY73093.1 - 3e-06 27.2 0.5 1e-05 25.4 0.4 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PHY PF00360.20 ORY73094.1 - 5e-26 91.1 0.0 1.1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 ORY73094.1 - 2.8e-17 63.2 0.1 6.2e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 ORY73094.1 - 7.2e-14 52.6 0.0 1.4e-12 48.4 0.0 2.6 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.24 ORY73094.1 - 2.5e-13 50.2 0.0 1e-12 48.2 0.0 2.0 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY73094.1 - 4.2e-12 45.9 1.4 4.2e-12 45.9 1.4 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 ORY73094.1 - 2.5e-08 34.5 0.0 5.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 ORY73095.1 - 2.3e-07 30.8 9.9 5.1e-07 29.7 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TerB_C PF15615.6 ORY73095.1 - 0.055 13.8 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 TerB-C domain bZIP_1 PF00170.21 ORY73096.1 - 5.2e-10 39.3 9.5 1.4e-09 37.9 9.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY73096.1 - 1.1e-07 31.8 11.5 1.1e-07 31.8 11.5 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY73096.1 - 0.01 16.3 7.4 0.01 16.3 7.4 2.3 3 0 0 3 3 3 0 bZIP Maf transcription factor TolA_bind_tri PF16331.5 ORY73096.1 - 0.017 15.2 0.3 0.036 14.1 0.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation TSC22 PF01166.18 ORY73096.1 - 0.079 13.3 0.4 0.16 12.3 0.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4407 PF14362.6 ORY73096.1 - 5.3 6.3 6.9 8.8 5.6 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cu_amine_oxid PF01179.20 ORY73098.1 - 4.3e-160 533.1 0.1 1.8e-159 531.1 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORY73098.1 - 5.4e-19 68.5 0.1 1.1e-18 67.5 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 ORY73098.1 - 0.00085 19.5 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_1 PF00515.28 ORY73099.1 - 2.6e-18 65.0 0.5 1.4e-06 27.9 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY73099.1 - 1.9e-15 55.6 3.0 0.00039 20.3 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY73099.1 - 9.7e-14 50.8 0.5 0.002 17.8 0.1 3.7 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 ORY73099.1 - 6.7e-11 41.5 0.1 0.12 12.6 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY73099.1 - 2.8e-10 39.9 0.7 0.11 12.9 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY73099.1 - 4e-10 40.2 5.9 0.00014 22.4 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY73099.1 - 3.4e-07 30.7 2.4 0.018 15.5 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY73099.1 - 2.4e-06 27.9 4.2 0.49 11.3 0.0 4.9 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY73099.1 - 4.1e-06 26.5 1.6 3.8 7.8 0.0 4.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY73099.1 - 2.1e-05 24.6 3.2 0.2 11.8 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY73099.1 - 0.00018 21.8 0.3 0.019 15.3 0.0 3.6 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY73099.1 - 0.0025 18.1 11.1 0.0056 16.9 0.2 4.6 5 2 1 6 6 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY73099.1 - 0.031 14.1 6.7 5.3 7.0 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 ORY73099.1 - 0.036 13.1 0.5 0.14 11.1 0.1 1.9 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 ORY73099.1 - 0.1 13.3 1.3 28 5.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 ORY73099.1 - 0.11 12.4 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1641) GFA PF04828.14 ORY73100.1 - 1.1e-21 76.9 0.3 1.6e-21 76.4 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.6 ORY73100.1 - 0.034 14.5 3.5 0.88 10.0 0.6 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar PEX11 PF05648.14 ORY73102.1 - 4.5e-07 29.6 3.0 0.016 14.7 1.5 3.2 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) SPX PF03105.19 ORY73103.1 - 6.3 6.6 10.5 9.2 6.1 10.5 1.3 1 0 0 1 1 1 0 SPX domain Esterase PF00756.20 ORY73104.1 - 1.2e-41 143.0 0.0 1.4e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ORY73104.1 - 0.031 13.6 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY73104.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORY73104.1 - 0.099 13.2 0.7 0.24 12.0 0.7 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ORY73104.1 - 0.17 10.8 0.0 0.26 10.1 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme SET PF00856.28 ORY73105.1 - 3.1e-12 47.2 0.0 8.3e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY73105.1 - 4.6e-09 36.2 10.3 4.6e-09 36.2 10.3 3.6 3 1 0 3 3 3 1 MYND finger Meleagrin PF08189.11 ORY73105.1 - 0.11 12.2 1.9 0.35 10.6 1.9 1.8 1 0 0 1 1 1 0 Meleagrin/Cygnin family FAM75 PF14650.6 ORY73105.1 - 0.19 11.3 4.2 0.34 10.4 4.2 1.3 1 0 0 1 1 1 0 FAM75 family Adeno_E1B_55K_N PF04623.12 ORY73105.1 - 1.8 9.4 7.5 0.12 13.1 0.7 2.5 3 0 0 3 3 3 0 Adenovirus E1B protein N-terminus UQ_con PF00179.26 ORY73106.1 - 3.2e-19 69.0 0.0 5.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORY73106.1 - 0.00025 20.9 0.0 0.00065 19.5 0.0 1.7 1 0 0 1 1 1 1 UEV domain IBR PF01485.21 ORY73106.1 - 0.0066 16.7 2.7 0.012 15.8 2.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain RPN6_C_helix PF18503.1 ORY73106.1 - 0.1 12.4 0.2 0.24 11.1 0.2 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain DUF5320 PF17253.2 ORY73106.1 - 2.5 9.2 6.9 0.81 10.8 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Actin PF00022.19 ORY73107.1 - 1.5e-73 247.8 0.0 2.7e-72 243.7 0.0 2.2 1 1 0 1 1 1 1 Actin PALP PF00291.25 ORY73107.1 - 0.0026 17.2 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Lipase_3 PF01764.25 ORY73108.1 - 8.8e-15 54.8 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY73108.1 - 0.01 16.5 2.9 0.047 14.3 0.2 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L15e PF00827.17 ORY73109.1 - 2.9e-88 294.6 9.6 3.4e-88 294.4 9.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 GYD PF08734.11 ORY73109.1 - 0.061 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 GYD domain ADH_N PF08240.12 ORY73110.1 - 8.4e-10 38.5 0.2 9.6e-10 38.3 0.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TMEM252 PF15664.5 ORY73111.1 - 0.00064 19.4 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 Transmembrane protein 252 family LYRIC PF15686.5 ORY73111.1 - 0.12 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Herpes_gE PF02480.16 ORY73111.1 - 0.21 10.3 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Saf_2TM PF18303.1 ORY73111.1 - 0.24 11.0 0.3 0.41 10.2 0.0 1.4 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain SIC PF03482.13 ORY73111.1 - 0.92 9.7 4.9 5.7 7.2 0.6 2.5 2 0 0 2 2 2 0 sic protein repeat Ion_trans_2 PF07885.16 ORY73112.1 - 9.4e-29 99.2 33.7 1.1e-18 67.0 10.6 3.2 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.26 ORY73112.1 - 3.6e-05 23.7 1.9 0.039 13.8 1.4 2.4 2 0 0 2 2 2 2 Ligand-gated ion channel Ion_trans PF00520.31 ORY73112.1 - 0.00016 21.0 18.4 0.017 14.3 4.7 2.6 2 1 0 2 2 2 2 Ion transport protein 7TMR-DISM_7TM PF07695.11 ORY73112.1 - 0.00052 20.0 2.5 0.00052 20.0 2.5 3.0 2 1 1 3 3 3 1 7TM diverse intracellular signalling CobU PF02283.16 ORY73112.1 - 0.74 9.4 6.0 0.36 10.4 2.8 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase MFMR_assoc PF16596.5 ORY73113.1 - 0.079 13.4 4.6 0.2 12.1 4.6 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR RPN2_C PF18004.1 ORY73113.1 - 5.9 6.8 8.4 14 5.6 8.4 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 ORY73113.1 - 7.4 4.5 11.3 12 3.8 11.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi Xan_ur_permease PF00860.20 ORY73114.1 - 7.5e-54 182.9 35.7 1.7e-53 181.8 35.7 1.5 1 1 0 1 1 1 1 Permease family DUF4418 PF14387.6 ORY73114.1 - 0.035 14.3 0.2 0.035 14.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4418) dCMP_cyt_deam_1 PF00383.23 ORY73115.1 - 9.7e-12 44.7 0.4 1.7e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY73115.1 - 3e-07 30.3 0.0 5.9e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 MafB19-like deaminase RNase_PH PF01138.21 ORY73116.1 - 4.4e-16 59.6 0.0 6.3e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ADH_N PF08240.12 ORY73118.1 - 2e-23 82.4 6.9 3e-23 81.8 5.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY73118.1 - 0.00025 21.0 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TFIIF_beta PF02270.15 ORY73119.1 - 3e-26 91.3 0.1 4.8e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 ORY73119.1 - 8e-14 52.5 0.0 1.9e-13 51.3 0.0 1.7 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 ORY73119.1 - 0.0005 20.9 0.0 0.00077 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain STALD PF18185.1 ORY73119.1 - 0.052 12.9 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Sir2- and TIR-associating SLOG family Jnk-SapK_ap_N PF09744.9 ORY73207.1 - 0.099 12.9 1.0 9.3 6.4 0.0 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HEAT_EZ PF13513.6 ORY73208.1 - 4.7 7.8 6.4 2.7 8.6 0.3 3.7 5 0 0 5 5 5 0 HEAT-like repeat IF-2B PF01008.17 ORY73209.1 - 3.7e-75 252.7 0.0 4.6e-75 252.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1308 PF07000.11 ORY73209.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1308) F-box-like PF12937.7 ORY73210.1 - 3.6e-07 30.0 3.4 5.6e-07 29.3 1.2 2.6 3 0 0 3 3 3 1 F-box-like TPR_1 PF00515.28 ORY73210.1 - 2.7e-06 26.9 1.7 0.018 14.9 0.3 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.33 ORY73210.1 - 0.0013 18.6 0.1 0.04 13.8 0.1 2.8 2 0 0 2 2 2 1 F-box domain TPR_8 PF13181.6 ORY73210.1 - 0.0033 17.5 1.9 0.87 10.0 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY73210.1 - 0.004 17.1 3.5 1.3 9.3 0.3 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat F-box_5 PF18511.1 ORY73210.1 - 0.018 14.6 0.5 0.041 13.4 0.5 1.6 1 0 0 1 1 1 0 F-box LRR_4 PF12799.7 ORY73210.1 - 0.047 14.1 4.9 13 6.4 0.1 5.1 4 2 3 7 7 7 0 Leucine Rich repeats (2 copies) ANAPC3 PF12895.7 ORY73210.1 - 0.06 13.6 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 ORY73210.1 - 0.2 10.5 0.1 0.3 10.0 0.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 LRR_6 PF13516.6 ORY73210.1 - 0.75 10.0 4.9 7.6 6.9 0.0 5.0 7 0 0 7 7 6 0 Leucine Rich repeat TPR_14 PF13428.6 ORY73210.1 - 0.79 10.7 3.3 13 6.9 0.1 3.8 3 1 0 4 4 3 0 Tetratricopeptide repeat GST_N_3 PF13417.6 ORY73211.1 - 7.3e-13 48.7 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY73211.1 - 1.1e-11 44.8 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY73211.1 - 8.4e-09 35.6 0.0 1.6e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY73211.1 - 6.1e-07 29.6 0.0 9.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY73211.1 - 3.5e-05 23.9 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY73211.1 - 6.8e-05 22.8 0.0 0.00027 20.9 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_transf_5 PF08323.11 ORY73213.1 - 4.7e-12 46.1 0.1 8.9e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 ORY73213.1 - 7.7e-07 29.6 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORY73213.1 - 6.3e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY73213.1 - 0.0025 18.3 0.0 0.0077 16.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 ORY73213.1 - 0.026 14.5 0.2 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 V-SNARE PF05008.15 ORY73215.1 - 1.1e-11 44.9 1.3 1.1e-11 44.9 1.3 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORY73215.1 - 1.6e-11 44.3 2.7 1.6e-11 44.3 2.7 2.3 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY73215.1 - 0.0054 16.6 1.6 0.032 14.2 0.0 2.7 2 2 1 3 3 3 1 Sec20 BLOC1_2 PF10046.9 ORY73215.1 - 0.058 13.7 6.0 0.29 11.5 0.3 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBCC_N PF16752.5 ORY73215.1 - 0.26 11.7 5.9 1.3 9.5 1.1 2.3 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain SNARE PF05739.19 ORY73215.1 - 0.51 10.4 4.8 4.3 7.4 4.8 2.4 1 1 0 1 1 1 0 SNARE domain MCU PF04678.13 ORY73215.1 - 1.2 9.2 4.2 9.1 6.3 0.6 2.2 2 1 0 2 2 2 0 Mitochondrial calcium uniporter Pkinase PF00069.25 ORY73218.1 - 1.2e-62 211.6 0.0 1.5e-62 211.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY73218.1 - 3.9e-28 98.4 0.0 5.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY73218.1 - 3.3e-06 26.1 0.3 3.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY73218.1 - 7.2e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY73218.1 - 0.00036 20.5 0.4 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORY73218.1 - 0.085 12.5 0.1 1.1 8.8 0.0 2.4 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Dus PF01207.17 ORY73219.1 - 2.5e-56 191.0 0.0 3.6e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) EI24 PF07264.11 ORY73220.1 - 6.2e-07 29.8 4.7 1e-06 29.1 4.3 1.6 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) UvdE PF03851.14 ORY73221.1 - 6.6e-101 337.2 0.0 8.7e-101 336.8 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE AP_endonuc_2 PF01261.24 ORY73221.1 - 0.00026 20.5 0.0 0.00066 19.2 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Sad1_UNC PF07738.13 ORY73224.1 - 3.8e-25 88.4 0.0 1.2e-13 51.2 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal APG6_N PF17675.1 ORY73224.1 - 0.0028 18.2 1.4 0.0028 18.2 1.4 2.4 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF948 PF06103.11 ORY73224.1 - 0.076 13.3 1.4 0.11 12.7 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 ORY73224.1 - 0.29 11.7 3.0 0.33 11.5 0.4 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 ORY73224.1 - 0.78 10.0 7.9 2.9 8.2 0.8 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 ORY73224.1 - 1.1 8.0 10.8 0.079 11.8 1.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein FliJ PF02050.16 ORY73224.1 - 1.9 8.7 6.8 0.6 10.3 0.3 2.5 3 0 0 3 3 3 0 Flagellar FliJ protein Jnk-SapK_ap_N PF09744.9 ORY73224.1 - 2.9 8.1 9.0 0.25 11.6 1.2 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 FlaC_arch PF05377.11 ORY73224.1 - 3.7 8.0 6.0 14 6.2 0.1 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 ORY73224.1 - 9.2 6.4 14.4 0.58 10.4 3.4 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) CHZ PF09649.10 ORY73225.1 - 2e-10 40.0 0.2 2e-10 40.0 0.2 3.0 2 1 1 3 3 3 1 Histone chaperone domain CHZ BUD22 PF09073.10 ORY73225.1 - 9.1 5.5 29.9 10 5.3 29.9 1.0 1 0 0 1 1 1 0 BUD22 IBN_N PF03810.19 ORY73226.1 - 4.2e-11 42.6 0.0 2.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ORY73226.1 - 0.003 17.6 0.0 0.019 15.0 0.0 2.4 1 0 0 1 1 1 1 Exportin 1-like protein CAS_CSE1 PF03378.15 ORY73226.1 - 0.1 11.1 0.1 0.39 9.1 0.0 1.8 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus Pkinase PF00069.25 ORY73227.1 - 2.2e-10 40.3 0.0 2.7e-08 33.5 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY73227.1 - 1.4e-08 34.4 0.0 6.9e-07 28.8 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase F-box-like PF12937.7 ORY73228.1 - 0.0014 18.5 0.3 0.0044 16.9 0.3 1.9 1 1 0 1 1 1 1 F-box-like BRK PF07533.16 ORY73228.1 - 0.057 13.0 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 BRK domain Syntaxin PF00804.25 ORY73230.1 - 1.7e-29 102.9 13.8 2.7e-29 102.3 13.8 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY73230.1 - 9.4e-12 44.7 0.9 9.4e-12 44.7 0.9 2.4 3 0 0 3 3 2 1 SNARE domain Syntaxin_2 PF14523.6 ORY73230.1 - 1.1e-05 25.7 6.8 1.1e-05 25.7 6.8 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.21 ORY73230.1 - 0.00037 20.2 5.2 0.00037 20.2 5.2 2.4 2 0 0 2 2 2 1 Synaptobrevin Baculo_PEP_C PF04513.12 ORY73230.1 - 0.00082 19.4 10.3 0.0018 18.3 0.9 2.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.21 ORY73230.1 - 0.0038 17.0 5.7 0.0038 17.0 5.7 2.5 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain CrgA PF06781.12 ORY73230.1 - 0.038 14.1 0.3 0.12 12.4 0.3 1.9 1 0 0 1 1 1 0 Cell division protein CrgA ECSCR PF15820.5 ORY73230.1 - 0.067 13.0 1.3 0.18 11.7 1.3 1.7 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Use1 PF09753.9 ORY73230.1 - 0.088 12.5 16.2 0.38 10.5 16.2 1.8 1 1 0 1 1 1 0 Membrane fusion protein Use1 IL11 PF07400.11 ORY73230.1 - 0.13 11.9 2.0 0.64 9.6 0.1 2.2 2 0 0 2 2 2 0 Interleukin 11 Allexi_40kDa PF05549.11 ORY73230.1 - 0.22 11.0 8.2 0.46 9.9 0.7 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein Herpes_US9 PF06072.11 ORY73230.1 - 0.24 11.3 2.0 0.53 10.2 2.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Mobilization_B PF17511.2 ORY73230.1 - 0.45 10.9 12.6 1.7 9.0 0.4 2.8 2 1 0 2 2 2 0 Mobilization protein B GCN5L1 PF06320.13 ORY73230.1 - 0.73 10.0 16.4 2.3 8.4 3.9 3.5 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) DASH_Dam1 PF08653.10 ORY73230.1 - 0.99 9.3 3.9 2.5 7.9 0.2 2.7 3 0 0 3 3 3 0 DASH complex subunit Dam1 BLOC1_2 PF10046.9 ORY73230.1 - 1 9.7 11.1 1.5 9.2 0.9 3.6 3 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.6 ORY73230.1 - 1.9 8.8 17.0 0.4 11.0 1.7 2.7 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF745 PF05335.13 ORY73230.1 - 3.4 7.4 20.5 2.6 7.7 13.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Spectrin PF00435.21 ORY73230.1 - 5.5 7.5 12.5 0.99 9.9 0.8 2.8 2 1 1 3 3 3 0 Spectrin repeat Mer2 PF09074.10 ORY73230.1 - 6.5 6.5 12.6 0.09 12.6 1.4 2.3 2 1 0 2 2 2 0 Mer2 IML1 PF12257.8 ORY73231.1 - 1.1e-93 313.4 0.0 1.6e-93 313.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 MFS_1 PF07690.16 ORY73232.1 - 2.7e-39 135.1 38.4 2.7e-39 135.1 38.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 ORY73233.1 - 2.9e-06 27.3 9.8 4.8e-06 26.6 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Syntaxin PF00804.25 ORY73234.1 - 3.6e-27 95.3 2.0 7e-27 94.4 2.0 1.5 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY73234.1 - 6.6e-11 42.0 1.8 2.2e-10 40.4 1.8 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 ORY73234.1 - 0.0068 16.8 0.9 0.0068 16.8 0.9 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Syntaxin-6_N PF09177.11 ORY73234.1 - 0.045 14.3 1.0 0.23 12.1 0.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Shisa PF13908.6 ORY73234.1 - 0.05 13.9 3.4 0.15 12.3 3.4 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ECSCR PF15820.5 ORY73234.1 - 0.065 13.1 1.0 0.13 12.1 1.0 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator SP_C-Propep PF08999.10 ORY73234.1 - 0.17 11.7 1.8 0.37 10.6 1.8 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF16 PF01519.16 ORY73234.1 - 2.4 8.7 4.6 2.3 8.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 KdgT PF03812.13 ORY73234.1 - 6.6 6.0 10.2 9.4 5.5 10.2 1.1 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease Phage_min_tail PF05939.13 ORY73235.1 - 0.073 13.5 0.2 0.19 12.2 0.2 1.7 1 0 0 1 1 1 0 Phage minor tail protein Cwf_Cwc_15 PF04889.12 ORY73235.1 - 1.2 8.9 6.8 1.5 8.5 0.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PAT1 PF09770.9 ORY73235.1 - 8.8 4.5 12.1 12 4.0 12.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAS4 PF15460.6 ORY73236.1 - 0.00065 19.8 0.4 0.0017 18.4 0.4 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 CDC45 PF02724.14 ORY73236.1 - 7.4 4.7 10.7 14 3.8 10.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Dor1 PF04124.12 ORY73237.1 - 8e-21 74.1 0.2 2.3e-17 62.7 0.2 3.2 2 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 ORY73237.1 - 3.3e-05 23.9 0.0 9.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 MFS_1 PF07690.16 ORY73238.1 - 1.3e-21 76.9 21.2 1.3e-21 76.9 21.2 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily HSP20 PF00011.21 ORY73238.1 - 4.8e-09 36.3 0.0 1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY73238.1 - 0.00017 21.1 0.0 0.00046 19.7 0.0 1.7 2 0 0 2 2 2 1 HSP20-like domain found in ArsA OATP PF03137.20 ORY73238.1 - 0.053 11.8 0.2 0.12 10.6 0.2 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ORY73239.1 - 3.6e-33 115.0 39.3 3.6e-33 115.0 39.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SLAC1 PF03595.17 ORY73240.1 - 7.8e-81 271.8 42.3 9.2e-81 271.6 42.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TPR_2 PF07719.17 ORY73241.1 - 2.8e-29 98.9 3.1 4.9e-06 26.3 0.0 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORY73241.1 - 4.3e-25 86.5 0.2 8.6e-07 28.5 0.0 8.2 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY73241.1 - 7.7e-25 87.0 13.8 8.6e-10 38.8 0.0 7.4 5 2 2 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY73241.1 - 3e-24 85.0 0.6 4.8e-15 55.6 0.1 5.8 3 3 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORY73241.1 - 6.2e-16 57.2 0.7 0.011 15.9 0.0 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY73241.1 - 7e-16 58.6 11.2 1.3e-05 25.8 0.1 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY73241.1 - 1e-15 57.1 0.1 4e-05 23.2 0.0 6.4 5 2 2 7 7 7 3 TPR repeat TPR_19 PF14559.6 ORY73241.1 - 6.8e-15 55.3 0.1 0.015 15.8 0.1 6.7 5 1 2 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY73241.1 - 2.9e-14 52.5 8.0 0.018 15.8 0.1 7.9 5 1 2 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY73241.1 - 3.9e-11 42.2 2.7 1.3 9.2 0.0 6.8 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY73241.1 - 1.3e-09 37.6 4.5 0.069 13.0 0.0 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY73241.1 - 3.1e-08 33.4 0.1 0.16 12.4 0.0 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY73241.1 - 1.1e-07 32.0 4.6 3.6 8.4 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY73241.1 - 7.4e-05 22.8 10.1 0.00015 21.8 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY73241.1 - 0.00073 19.0 4.6 0.039 13.3 0.1 3.6 2 1 1 3 3 3 1 MalT-like TPR region TPR_15 PF13429.6 ORY73241.1 - 0.015 14.5 0.2 9.7 5.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 ORY73241.1 - 0.03 14.6 0.3 59 4.2 0.0 4.7 5 0 0 5 5 4 0 PPR repeat Fis1_TPR_C PF14853.6 ORY73241.1 - 0.042 13.9 0.3 6.6 6.9 0.1 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Ferritin PF00210.24 ORY73241.1 - 0.07 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Ferritin-like domain TPR_21 PF09976.9 ORY73241.1 - 0.085 12.6 0.0 19 4.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 ORY73241.1 - 1.3 9.9 20.9 1.9 9.3 0.5 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 ORY73242.1 - 3.6e-33 115.0 39.3 3.6e-33 115.0 39.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily HSP20 PF00011.21 ORY73243.1 - 2.9e-19 69.1 0.0 3.2e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY73243.1 - 1.2e-10 40.7 0.0 1.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 HSP20-like domain found in ArsA LRR_4 PF12799.7 ORY73244.1 - 3.2e-34 116.4 30.4 1.1e-08 35.2 0.8 7.2 3 1 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY73244.1 - 6.4e-26 89.9 27.6 7.4e-08 32.0 3.6 6.3 3 1 4 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 ORY73244.1 - 5.1e-13 48.9 6.4 1.8e-06 27.6 0.2 3.8 2 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 ORY73244.1 - 3.7e-06 26.5 18.6 0.0057 16.6 0.0 7.4 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 ORY73244.1 - 0.029 14.9 27.0 13 6.8 0.0 9.1 10 2 1 11 11 11 0 Leucine Rich Repeat Mfa1 PF17445.2 ORY73244.1 - 0.52 10.4 2.1 1 9.4 2.1 1.5 1 0 0 1 1 1 0 Mating factor A1 PXA PF02194.15 ORY73245.1 - 0.02 14.9 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 PXA domain HAD_2 PF13419.6 ORY73246.1 - 3.2e-07 30.6 0.0 7.2e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY73246.1 - 3.7e-05 24.1 0.0 0.00039 20.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY73246.1 - 0.0053 16.8 0.0 0.0091 16.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like dsDNA_bind PF01984.20 ORY73247.1 - 1.8e-35 121.6 1.2 2.1e-35 121.3 1.2 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain M_domain PF12938.7 ORY73247.1 - 0.0079 16.0 1.4 0.012 15.4 1.4 1.2 1 0 0 1 1 1 1 M domain of GW182 DUF4766 PF15973.5 ORY73247.1 - 0.014 16.0 1.4 0.014 16.0 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) zf-C3HC4_3 PF13920.6 ORY73248.1 - 5.6e-08 32.5 5.8 7.9e-08 32.0 5.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY73248.1 - 1.3e-07 31.8 10.5 1.9e-07 31.3 10.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY73248.1 - 3e-07 30.2 7.7 4.6e-07 29.6 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY73248.1 - 1.6e-06 27.9 9.2 2.4e-06 27.3 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY73248.1 - 0.00094 19.1 7.2 0.0015 18.4 7.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY73248.1 - 0.0017 18.2 7.9 0.0029 17.4 7.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY73248.1 - 0.0031 17.5 5.4 0.0058 16.6 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY73248.1 - 0.0031 17.7 7.5 0.0057 16.9 7.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain DZR PF12773.7 ORY73248.1 - 0.39 10.8 4.4 0.67 10.0 4.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon MUG113 PF13455.6 ORY73249.1 - 5e-08 33.5 0.2 2.8e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 ORY73249.1 - 5.4e-06 26.9 0.9 6e-05 23.5 0.9 2.1 1 1 0 1 1 1 1 T5orf172 domain DUF4317 PF14199.6 ORY73250.1 - 0.0097 15.1 0.1 0.014 14.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4317) Fungal_trans PF04082.18 ORY73251.1 - 5.7e-35 120.6 0.1 9.9e-35 119.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY73251.1 - 3.3e-08 33.5 8.6 5.2e-08 32.9 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ORY73252.1 - 1.6e-66 225.0 0.0 2.2e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TrbI PF03743.14 ORY73252.1 - 0.054 13.3 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein GTP_EFTU PF00009.27 ORY73253.1 - 1.6e-44 151.8 0.0 2.5e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 ORY73253.1 - 2.1e-38 130.8 0.6 3.6e-38 130.0 0.6 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 ORY73253.1 - 9.7e-15 54.4 0.0 2.1e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY73253.1 - 4.1e-06 27.1 0.2 9.4e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY73253.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain HORMA PF02301.18 ORY73254.1 - 7.9e-25 87.7 0.1 9.3e-25 87.5 0.1 1.0 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 ORY73254.1 - 0.0046 16.8 0.1 0.01 15.7 0.1 1.6 1 1 0 1 1 1 1 Bacterial HORMA domain 2 EcsC PF12787.7 ORY73254.1 - 0.091 12.4 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 EcsC protein family AA_permease_2 PF13520.6 ORY73255.1 - 1.7e-77 261.1 48.3 2.3e-77 260.6 48.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY73255.1 - 5.1e-14 51.7 42.2 8.2e-14 51.1 42.1 1.3 1 1 0 1 1 1 1 Amino acid permease HSP20 PF00011.21 ORY73256.1 - 1.1e-19 70.4 0.1 1.3e-19 70.2 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY73256.1 - 3.8e-10 39.2 0.0 5.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA TubC_N PF18563.1 ORY73256.1 - 0.025 14.6 0.0 2.8 8.0 0.0 2.2 2 0 0 2 2 2 0 TubC N-terminal docking domain HA2 PF04408.23 ORY73257.1 - 1.2e-16 61.0 0.0 3.4e-16 59.5 0.0 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY73257.1 - 4e-14 52.9 0.3 1.1e-13 51.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY73257.1 - 7.8e-12 45.3 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 ORY73257.1 - 2.8e-10 40.4 0.0 7.9e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 ORY73257.1 - 0.00025 21.3 0.1 0.00093 19.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY73257.1 - 0.0015 17.7 0.0 0.003 16.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 ORY73257.1 - 0.023 14.7 0.0 0.17 11.8 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 ORY73257.1 - 0.037 13.5 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ORY73257.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 ORY73257.1 - 0.091 12.7 0.0 0.34 10.8 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ORY73257.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY73257.1 - 0.17 12.2 0.0 0.42 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Sin3a_C PF16879.5 ORY73258.1 - 2.2e-74 250.7 0.0 8e-74 248.9 0.0 2.0 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY73258.1 - 1.9e-40 136.7 7.7 1.9e-17 63.1 0.6 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY73258.1 - 2.6e-35 120.4 0.1 1.2e-34 118.3 0.0 2.1 2 0 0 2 2 2 1 Sin3 family co-repressor Baculo_PP31 PF05311.11 ORY73258.1 - 4.3 6.7 7.6 6.5 6.2 0.6 2.5 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) HATPase_c PF02518.26 ORY73259.1 - 4.7e-18 65.7 0.1 9.6e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY73259.1 - 1.1e-12 48.1 0.0 2.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY73259.1 - 1.8e-10 40.7 0.0 6e-10 39.0 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain CBP4 PF07960.11 ORY73259.1 - 0.026 14.4 0.3 0.057 13.3 0.3 1.5 1 0 0 1 1 1 0 CBP4 Mito_carr PF00153.27 ORY73260.1 - 3.2e-39 132.7 7.4 9e-18 64.0 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein HSP20 PF00011.21 ORY73261.1 - 2.6e-20 72.5 0.1 2.8e-20 72.4 0.1 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY73261.1 - 2e-11 43.3 0.0 2.7e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA TubC_N PF18563.1 ORY73261.1 - 0.12 12.4 0.0 18 5.4 0.0 2.2 2 0 0 2 2 2 0 TubC N-terminal docking domain TFIIIC_sub6 PF10419.9 ORY73262.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain DUF3180 PF11377.8 ORY73263.1 - 0.044 13.9 0.1 0.044 13.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) TMEM154 PF15102.6 ORY73263.1 - 0.34 10.8 0.0 0.34 10.8 0.0 4.1 3 1 0 4 4 4 0 TMEM154 protein family GT87 PF09594.10 ORY73263.1 - 0.36 10.5 4.7 0.63 9.7 4.7 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 87 DHHC PF01529.20 ORY73264.1 - 1.4e-30 106.2 1.7 1.4e-30 106.2 1.7 2.5 3 0 0 3 3 3 1 DHHC palmitoyltransferase Syntaphilin PF15290.6 ORY73264.1 - 0.013 15.2 1.2 0.018 14.7 1.2 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp AAA PF00004.29 ORY73265.1 - 4.8e-86 285.9 0.0 5.6e-42 143.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY73265.1 - 2.7e-25 87.9 0.1 3.2e-13 49.2 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORY73265.1 - 8.3e-12 45.1 0.0 6.8e-05 22.7 0.0 3.2 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY73265.1 - 1.8e-11 44.2 3.5 1.7e-06 28.1 0.8 4.3 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY73265.1 - 6.1e-10 39.7 1.6 0.00024 21.5 0.1 4.0 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.13 ORY73265.1 - 4.4e-09 36.0 0.0 0.0029 16.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 ORY73265.1 - 5.2e-08 33.3 1.8 0.0056 16.9 0.3 4.5 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 ORY73265.1 - 1.8e-07 31.4 0.0 0.039 14.1 0.0 2.9 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 ORY73265.1 - 6.1e-07 29.2 7.6 0.03 13.9 0.0 4.6 3 2 1 5 5 5 2 AAA domain RNA_helicase PF00910.22 ORY73265.1 - 1.4e-06 28.6 0.0 0.03 14.7 0.0 3.4 3 0 0 3 3 3 2 RNA helicase ATPase PF06745.13 ORY73265.1 - 4.5e-06 26.2 0.1 0.58 9.5 0.0 3.3 3 0 0 3 3 3 2 KaiC IstB_IS21 PF01695.17 ORY73265.1 - 1.4e-05 24.9 0.0 0.034 13.9 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY73265.1 - 2.7e-05 23.6 0.3 0.21 10.9 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORY73265.1 - 3.3e-05 23.9 0.0 0.029 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY73265.1 - 3.3e-05 24.1 0.0 0.22 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 ORY73265.1 - 7.9e-05 22.5 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY73265.1 - 0.00011 22.7 0.1 0.19 12.3 0.0 3.1 3 1 0 3 3 2 1 AAA domain Rad17 PF03215.15 ORY73265.1 - 0.00037 20.5 0.1 0.033 14.1 0.0 3.2 2 2 1 3 3 3 1 Rad17 P-loop domain Vps4_C PF09336.10 ORY73265.1 - 0.00039 20.3 0.0 0.063 13.3 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 ORY73265.1 - 0.001 19.3 0.7 0.77 10.0 0.0 3.0 2 1 1 3 3 2 1 AAA domain AAA_7 PF12775.7 ORY73265.1 - 0.0022 17.6 0.0 0.78 9.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 ORY73265.1 - 0.0029 17.6 0.0 1.5 8.8 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORY73265.1 - 0.0091 15.9 0.2 1.2 9.0 0.0 3.5 3 1 0 3 3 2 1 NACHT domain Parvo_NS1 PF01057.17 ORY73265.1 - 0.013 14.6 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 ORY73265.1 - 0.015 15.1 0.0 5.6 6.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 ORY73265.1 - 0.019 14.7 0.4 0.89 9.3 0.4 2.8 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ORY73265.1 - 0.02 14.6 0.0 5.8 6.6 0.0 3.5 3 1 0 3 3 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 ORY73265.1 - 0.058 13.9 0.0 5.4 7.5 0.0 2.7 2 1 0 2 2 2 0 ABC transporter PhoH PF02562.16 ORY73265.1 - 0.06 12.8 1.3 1.1 8.7 0.0 2.8 3 0 0 3 3 3 0 PhoH-like protein DUF2075 PF09848.9 ORY73265.1 - 0.069 12.4 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 ORY73265.1 - 0.077 13.1 0.0 7.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DALR_2 PF09190.11 ORY73265.1 - 0.089 13.3 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 DALR domain RecA PF00154.21 ORY73265.1 - 0.18 11.3 0.2 1.7 8.1 0.1 2.3 1 1 1 2 2 2 0 recA bacterial DNA recombination protein Importin_rep_4 PF18808.1 ORY73265.1 - 0.26 11.6 1.6 0.67 10.3 1.6 1.6 1 0 0 1 1 1 0 Importin repeat AAA_19 PF13245.6 ORY73265.1 - 0.57 10.5 2.1 1.6 9.0 0.3 2.4 2 1 0 2 2 2 0 AAA domain CLTH PF10607.9 ORY73266.1 - 4.9e-31 107.6 0.0 8.6e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Ku PF02735.16 ORY73268.1 - 9e-22 77.8 0.0 3e-21 76.0 0.0 1.9 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 ORY73268.1 - 1.7e-08 34.6 0.0 3.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like VWA PF00092.28 ORY73268.1 - 0.1 12.8 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain Peptidase_Mx1 PF15890.5 ORY73268.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase UQ_con PF00179.26 ORY73269.1 - 8.1e-49 164.9 0.1 9.2e-49 164.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY73269.1 - 0.0042 16.8 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY73269.1 - 0.011 16.0 3.8 0.035 14.4 3.8 1.8 1 1 0 1 1 1 0 RWD domain HBM PF16591.5 ORY73270.1 - 0.062 12.7 0.6 2.3 7.6 0.1 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain mRNA_cap_enzyme PF01331.19 ORY73271.1 - 8.7e-36 123.6 0.0 1.2e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ORY73271.1 - 2e-27 95.9 0.1 3.1e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 ORY73271.1 - 1.2e-07 31.6 0.0 4.9e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Hist_deacetyl PF00850.19 ORY73395.1 - 3.4e-50 171.3 0.0 5.7e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain HSF_DNA-bind PF00447.17 ORY73396.1 - 4.6e-20 72.0 0.0 7.1e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding C2 PF00168.30 ORY73397.1 - 1.6e-27 95.7 0.0 5.2e-18 65.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 ORY73397.1 - 0.077 12.5 0.0 0.35 10.3 0.0 1.9 2 0 0 2 2 2 0 Synaptotagmin-like mitochondrial-lipid-binding domain Lipase_GDSL_2 PF13472.6 ORY73398.1 - 0.091 13.2 0.1 0.29 11.5 0.1 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family CTP_synth_N PF06418.14 ORY73399.1 - 2.6e-124 413.8 0.0 3.4e-124 413.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ORY73399.1 - 3.4e-52 177.0 0.0 5.7e-52 176.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY73399.1 - 0.09 12.5 0.1 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 Sulfate_transp PF00916.20 ORY73400.1 - 3.6e-79 266.3 21.5 5.5e-79 265.7 21.5 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY73400.1 - 5.9e-12 45.3 0.0 1.1e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF2721 PF11026.8 ORY73400.1 - 0.026 14.4 0.0 0.026 14.4 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) Sec5 PF15469.6 ORY73403.1 - 1.4e-48 165.3 0.0 5.9e-48 163.2 0.0 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec5 V_ATPase_I_N PF18670.1 ORY73403.1 - 0.087 13.2 0.0 0.38 11.2 0.0 2.1 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain LCAT PF02450.15 ORY73404.1 - 5.2e-83 279.4 0.3 2.7e-75 254.0 0.2 2.0 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ORY73404.1 - 0.01 16.5 0.0 0.028 15.0 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family DENN PF02141.21 ORY73405.1 - 4.1e-15 56.2 0.1 6.4e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF4303 PF14136.6 ORY73405.1 - 0.52 10.0 3.6 0.5 10.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Prominin PF05478.11 ORY73405.1 - 1.1 7.2 4.1 1.6 6.6 4.1 1.1 1 0 0 1 1 1 0 Prominin Seryl_tRNA_N PF02403.22 ORY73405.1 - 1.1 9.5 7.3 4 7.7 7.3 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4600 PF15372.6 ORY73405.1 - 1.4 9.4 11.8 0.2 12.1 7.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Sin_N PF04801.13 ORY73406.1 - 1.1e-34 120.4 0.1 1.7e-34 119.8 0.1 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region AP3D1 PF06375.11 ORY73406.1 - 0.022 15.0 3.0 0.022 15.0 3.0 2.5 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Med19 PF10278.9 ORY73406.1 - 0.72 9.8 12.2 0.22 11.4 6.4 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 RNA_pol_Rpc4 PF05132.14 ORY73406.1 - 3.6 8.0 5.8 4.4 7.7 0.9 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DnaJ PF00226.31 ORY73407.1 - 7.3e-18 64.5 0.0 1.4e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain NAP PF00956.18 ORY73407.1 - 0.0017 17.6 0.1 0.0023 17.2 0.1 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Gly-zipper_YMGG PF13441.6 ORY73407.1 - 0.0024 17.5 12.6 0.0053 16.5 12.6 1.5 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 ORY73407.1 - 0.0051 16.8 12.1 0.011 15.7 12.1 1.5 1 0 0 1 1 1 1 Glycine zipper Rick_17kDa_Anti PF05433.15 ORY73407.1 - 0.63 10.0 16.7 3.4 7.6 5.9 2.5 1 1 1 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.9 ORY73407.1 - 1.4 9.1 12.7 3.2 8.0 12.7 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.6 ORY73407.1 - 3.9 7.3 18.4 4.4 7.2 7.3 2.2 1 1 1 2 2 2 0 Glycine-zipper domain His_Phos_1 PF00300.22 ORY73408.1 - 8e-13 48.5 0.1 2.4e-12 46.9 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Mito_carr PF00153.27 ORY73410.1 - 1.1e-73 243.3 0.5 4.1e-24 84.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GAD-like PF08887.11 ORY73410.1 - 0.072 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 GAD-like domain Serine_protease PF18405.1 ORY73410.1 - 0.11 11.6 0.9 17 4.5 0.0 3.4 2 1 2 4 4 4 0 Gammaproteobacterial serine protease DUF591 PF04569.14 ORY73411.1 - 0.18 11.8 0.3 0.18 11.8 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function CAP_N PF01213.19 ORY73411.1 - 4.4 6.7 8.7 6.7 6.1 1.0 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ARID PF01388.21 ORY73412.1 - 2.3e-22 79.5 0.0 6.1e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 ORY73412.1 - 0.036 13.4 0.5 0.12 11.6 0.1 2.0 3 0 0 3 3 3 0 SWI/SNF-like complex subunit BAF250/Osa HlyIII PF03006.20 ORY73413.1 - 3.3e-59 200.3 13.0 4.1e-59 200.0 13.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 ORY73413.1 - 0.0074 16.3 1.1 0.0074 16.3 1.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF962) SANT_DAMP1_like PF16282.5 ORY73416.1 - 1.6e-27 95.5 1.3 2.6e-27 94.8 1.3 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 PALP PF00291.25 ORY73416.1 - 0.067 12.6 0.1 0.067 12.6 0.1 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 ORY73416.1 - 0.19 11.6 0.0 0.54 10.1 0.0 1.8 1 0 0 1 1 1 0 ACT domain DUF755 PF05501.11 ORY73416.1 - 0.22 11.8 5.4 0.49 10.7 5.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Acetyltransf_10 PF13673.7 ORY73417.1 - 4.3e-06 26.7 0.1 7.5e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY73417.1 - 1.7e-05 25.2 0.1 5.2e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY73417.1 - 0.0036 17.2 0.1 0.0071 16.3 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ORY73417.1 - 0.0082 16.4 0.1 0.023 14.9 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY73417.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY73417.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ADH_zinc_N_2 PF13602.6 ORY73418.1 - 5.3e-14 53.4 0.0 1.2e-13 52.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY73418.1 - 3.5e-12 46.4 0.0 5.5e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY73418.1 - 2.1e-06 27.6 0.0 4.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AAA_2 PF07724.14 ORY73419.1 - 1.5e-48 165.2 0.0 2.2e-45 154.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORY73419.1 - 5.7e-29 100.1 1.8 5.7e-29 100.1 1.8 3.2 3 0 0 3 3 2 1 AAA lid domain ClpB_D2-small PF10431.9 ORY73419.1 - 2.7e-23 81.8 0.8 8.1e-23 80.3 0.0 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ORY73419.1 - 3.5e-22 79.3 0.0 1.1e-11 45.3 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 ORY73419.1 - 3.1e-16 59.2 2.3 1.3e-10 41.2 0.1 3.3 2 1 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 ORY73419.1 - 5.6e-14 52.3 0.0 1.8e-08 34.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY73419.1 - 3.5e-11 43.8 10.7 1.3e-05 25.6 0.0 5.8 5 2 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 ORY73419.1 - 1.1e-08 35.4 0.1 0.034 14.4 0.0 4.4 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ORY73419.1 - 7.6e-08 32.2 0.0 0.00037 20.2 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORY73419.1 - 4.9e-07 29.6 0.0 0.0075 16.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 ORY73419.1 - 1e-06 28.3 0.0 0.0015 17.9 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 ORY73419.1 - 8.4e-06 26.0 0.1 0.041 14.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 ORY73419.1 - 0.0001 22.8 0.0 0.37 11.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 ORY73419.1 - 0.00011 21.5 3.1 0.088 12.0 0.0 3.5 4 0 0 4 4 4 2 TIP49 P-loop domain AAA_7 PF12775.7 ORY73419.1 - 0.00015 21.3 0.0 0.59 9.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY73419.1 - 0.00016 21.0 0.1 0.036 13.3 0.0 3.2 2 1 1 3 3 3 1 Zeta toxin RuvB_N PF05496.12 ORY73419.1 - 0.00018 21.3 0.2 0.9 9.3 0.0 3.7 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 ORY73419.1 - 0.00026 21.4 0.0 0.57 10.6 0.1 3.1 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 ORY73419.1 - 0.00043 20.1 0.0 0.19 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Cob_adeno_trans PF01923.18 ORY73419.1 - 0.00085 19.5 4.2 0.012 15.7 4.1 2.7 2 1 1 3 3 3 1 Cobalamin adenosyltransferase TsaE PF02367.17 ORY73419.1 - 0.0023 17.9 0.0 3.7 7.6 0.0 3.4 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ORY73419.1 - 0.0023 18.2 1.6 0.76 10.0 0.0 3.7 4 0 0 4 4 2 1 AAA domain Mg_chelatase PF01078.21 ORY73419.1 - 0.0025 17.2 0.0 0.72 9.2 0.0 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI Not3 PF04065.15 ORY73419.1 - 0.0038 16.7 5.4 0.0082 15.6 5.4 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component ABC_tran PF00005.27 ORY73419.1 - 0.0067 16.9 0.5 0.94 10.0 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ResIII PF04851.15 ORY73419.1 - 0.014 15.4 0.0 0.92 9.5 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit FapA PF03961.13 ORY73419.1 - 0.018 13.7 2.1 0.03 12.9 2.1 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A RsgA_GTPase PF03193.16 ORY73419.1 - 0.019 14.8 0.4 12 5.8 0.0 3.5 3 0 0 3 3 3 0 RsgA GTPase Torsin PF06309.11 ORY73419.1 - 0.025 14.7 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Torsin NACHT PF05729.12 ORY73419.1 - 0.031 14.2 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 ORY73419.1 - 0.032 14.5 0.0 14 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phlebovirus_NSM PF07246.11 ORY73419.1 - 0.034 13.5 4.2 0.067 12.5 4.2 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AAA_23 PF13476.6 ORY73419.1 - 0.039 14.4 0.0 0.039 14.4 0.0 3.7 4 1 1 5 5 3 0 AAA domain ATPase_2 PF01637.18 ORY73419.1 - 0.066 13.1 5.4 27 4.6 0.0 4.5 4 1 1 5 5 5 0 ATPase domain predominantly from Archaea APS_kinase PF01583.20 ORY73419.1 - 0.076 12.9 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Senescence PF06911.12 ORY73419.1 - 0.097 13.0 0.1 0.35 11.2 0.0 1.9 2 0 0 2 2 1 0 Senescence-associated protein NTPase_1 PF03266.15 ORY73419.1 - 0.11 12.3 0.1 8.3 6.3 0.0 3.2 2 1 0 2 2 2 0 NTPase AAA_6 PF12774.7 ORY73419.1 - 0.15 11.0 0.0 0.67 8.9 0.0 2.1 3 0 0 3 3 1 0 Hydrolytic ATP binding site of dynein motor region Laminin_II PF06009.12 ORY73419.1 - 0.26 11.3 8.3 0.12 12.4 4.3 2.3 1 1 1 2 2 2 0 Laminin Domain II AAA_13 PF13166.6 ORY73419.1 - 0.3 9.7 4.6 4.6 5.8 5.2 2.1 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 ORY73419.1 - 0.38 9.6 10.4 0.75 8.6 10.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Uds1 PF15456.6 ORY73419.1 - 0.47 10.6 14.0 0.16 12.1 10.2 2.2 2 0 0 2 2 1 0 Up-regulated During Septation DUF4337 PF14235.6 ORY73419.1 - 2.1 8.4 9.8 5.5 7.1 9.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Atg14 PF10186.9 ORY73419.1 - 8.3 5.4 7.8 20 4.2 7.8 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 F-box-like PF12937.7 ORY73420.1 - 3.6e-06 26.8 0.0 1.5e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.7 ORY73421.1 - 6.1e-06 26.0 0.3 1.5e-05 24.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like V-SNARE_C PF12352.8 ORY73422.1 - 6.9e-14 51.9 0.6 1.2e-13 51.1 0.6 1.4 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY73422.1 - 9.6e-05 22.2 0.0 0.00032 20.6 0.0 1.8 2 0 0 2 2 2 1 Sec20 HALZ PF02183.18 ORY73422.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper NDUF_C2 PF06374.11 ORY73422.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) FliD_N PF02465.18 ORY73422.1 - 0.5 11.1 7.2 3.4 8.4 0.6 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus RAP1 PF07218.11 ORY73422.1 - 6.1 5.0 5.1 7.4 4.7 5.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AA_permease PF00324.21 ORY73423.1 - 4.2e-104 348.8 36.1 5.2e-104 348.5 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY73423.1 - 2.8e-16 59.4 41.7 9.9e-16 57.6 34.2 2.0 1 1 1 2 2 2 2 Amino acid permease TruD PF01142.18 ORY73424.1 - 9.7e-67 225.6 0.0 2e-59 201.5 0.0 3.2 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Granin PF01271.17 ORY73424.1 - 0.042 12.8 1.6 0.071 12.0 1.6 1.2 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) Epimerase PF01370.21 ORY73425.1 - 1e-15 57.9 1.2 6.3e-15 55.3 1.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY73425.1 - 1.7e-14 54.1 0.2 2.3e-14 53.7 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY73425.1 - 2.2e-14 53.3 0.0 8.5e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 ORY73425.1 - 1.8e-13 50.2 0.0 7.4e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY73425.1 - 2.8e-08 33.6 0.0 1.1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY73425.1 - 3e-08 33.5 0.0 1.5e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY73425.1 - 6.4e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ORY73425.1 - 0.0059 16.1 0.4 0.12 11.9 0.0 2.6 3 0 0 3 3 3 1 short chain dehydrogenase RNase_T PF00929.24 ORY73426.1 - 1.1e-15 58.6 0.0 3.6e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ORY73426.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease DUF3854 PF12965.7 ORY73426.1 - 0.06 13.3 0.2 0.13 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) U1snRNP70_N PF12220.8 ORY73426.1 - 1.6 9.4 5.7 0.89 10.2 1.0 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TP_methylase PF00590.20 ORY73427.1 - 1.3e-17 64.5 0.0 2.5e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CENP-F_leu_zip PF10473.9 ORY73428.1 - 0.0032 17.5 20.2 0.0032 17.5 20.2 7.0 4 1 4 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dynamitin PF04912.14 ORY73428.1 - 0.0043 16.4 9.4 0.0043 16.4 9.4 4.2 1 1 2 4 4 4 2 Dynamitin HTH_19 PF12844.7 ORY73428.1 - 0.35 10.9 6.0 2.1 8.4 1.8 3.3 2 0 0 2 2 2 0 Helix-turn-helix domain HRDC PF00570.23 ORY73428.1 - 0.83 9.7 5.8 3.9 7.6 0.8 3.3 3 0 0 3 3 3 0 HRDC domain Fez1 PF06818.15 ORY73428.1 - 1.4 9.4 63.0 0.49 10.8 17.8 3.8 2 1 1 3 3 3 0 Fez1 Thaumatin PF00314.17 ORY73429.1 - 1.2e-65 221.1 8.5 1.5e-65 220.8 8.5 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 ORY73429.1 - 0.007 15.7 0.6 0.049 12.9 0.0 2.2 2 0 0 2 2 2 1 Beta-1,3-glucanase Linker_histone PF00538.19 ORY73430.1 - 1.1e-20 73.7 0.1 1.1e-20 73.7 0.1 2.6 2 1 0 2 2 2 1 linker histone H1 and H5 family HC2 PF07382.11 ORY73430.1 - 3.8e-10 40.2 82.9 3.8e-10 40.2 82.9 2.2 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 adh_short_C2 PF13561.6 ORY73431.1 - 1.8e-59 201.2 0.4 2.2e-59 200.9 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY73431.1 - 7.2e-43 146.3 0.1 8.6e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY73431.1 - 1.1e-11 45.0 0.1 2.3e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 ORY73431.1 - 0.03 14.8 0.1 0.21 12.0 0.1 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_4 PF07993.12 ORY73431.1 - 0.088 12.0 0.1 3.3 6.8 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Glyco_hydro_1 PF00232.18 ORY73431.1 - 0.13 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Cactin_mid PF10312.9 ORY73432.1 - 2.3e-65 220.1 2.3 2.3e-65 220.1 2.3 2.8 2 0 0 2 2 2 1 Conserved mid region of cactin CactinC_cactus PF09732.9 ORY73432.1 - 1.8e-58 195.9 5.3 2.9e-58 195.2 5.3 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Beta-lactamase PF00144.24 ORY73433.1 - 2.3e-33 115.9 0.0 2.8e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S13 PF02113.15 ORY73433.1 - 0.018 13.8 0.1 0.024 13.4 0.1 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family RAI16-like PF10257.9 ORY73434.1 - 1.8e-55 188.3 0.0 3.1e-55 187.5 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein F-box-like PF12937.7 ORY73435.1 - 1.2e-05 25.1 3.1 3.2e-05 23.7 3.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY73435.1 - 0.004 17.0 0.4 0.012 15.5 0.4 1.8 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ORY73435.1 - 0.049 14.1 0.4 41 4.8 0.1 4.4 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) EzrA PF06160.12 ORY73436.1 - 0.0072 14.6 1.6 0.0094 14.2 1.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4407 PF14362.6 ORY73436.1 - 2.5 7.4 8.9 3.5 6.9 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.7 ORY73437.1 - 5.8e-05 22.9 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 ORY73438.1 - 2.1e-21 76.3 23.7 2.9e-21 75.8 23.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 ORY73438.1 - 0.0026 16.7 0.3 0.0068 15.4 0.2 1.8 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM TMEM132D_C PF15706.5 ORY73438.1 - 0.052 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TauD PF02668.16 ORY73439.1 - 2e-49 168.8 0.0 2.6e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ENTH PF01417.20 ORY73440.1 - 2.1e-48 163.5 0.0 2.1e-48 163.5 0.0 1.5 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.16 ORY73440.1 - 7.5e-06 25.1 0.0 7.5e-06 25.1 0.0 2.0 2 0 0 2 2 2 1 ANTH domain AXH PF08517.12 ORY73440.1 - 0.13 12.9 0.1 0.13 12.9 0.1 3.1 2 1 1 3 3 3 0 Ataxin-1 and HBP1 module (AXH) DUF4771 PF15995.5 ORY73440.1 - 1.8 8.8 15.3 20 5.4 11.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) LMBR1 PF04791.16 ORY73440.1 - 2.6 6.9 5.0 3.3 6.5 5.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GREB1 PF15782.5 ORY73440.1 - 3.3 4.7 13.4 5.1 4.1 13.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Dak1 PF02733.17 ORY73441.1 - 2e-103 345.6 0.1 2.8e-103 345.1 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ORY73441.1 - 5.4e-39 133.9 2.7 8.9e-39 133.2 2.7 1.4 1 0 0 1 1 1 1 DAK2 domain NMO PF03060.15 ORY73442.1 - 1.8e-53 182.0 0.6 2.5e-52 178.4 0.6 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY73442.1 - 2.1e-09 36.8 0.0 1.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 ORY73442.1 - 0.048 13.0 0.3 0.098 12.0 0.0 1.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase FMN_dh PF01070.18 ORY73442.1 - 0.061 12.4 0.3 0.097 11.7 0.3 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1902 PF08972.11 ORY73442.1 - 0.09 12.8 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) His_biosynth PF00977.21 ORY73442.1 - 0.1 12.0 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein TPR_12 PF13424.6 ORY73443.1 - 4.8e-08 33.2 12.2 0.00017 21.8 0.2 4.5 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY73443.1 - 1.5e-07 31.8 12.3 0.00012 22.5 0.2 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY73443.1 - 2.9e-06 27.0 8.5 1.6 9.0 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY73443.1 - 3.4e-06 26.6 3.9 6.9 6.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY73443.1 - 7.2e-06 26.0 1.0 0.072 13.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY73443.1 - 8.8e-05 23.1 6.7 0.35 11.6 0.1 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY73443.1 - 0.00011 21.7 8.5 0.0095 15.3 0.5 3.2 2 1 1 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 ORY73443.1 - 0.00017 22.1 12.7 0.26 12.2 1.7 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY73443.1 - 0.0013 18.8 4.6 52 4.4 0.2 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY73443.1 - 0.0021 18.5 5.5 2.8 8.8 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY73443.1 - 0.0023 18.5 3.4 0.44 11.3 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY73443.1 - 0.042 14.1 1.3 0.65 10.3 0.1 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 ORY73443.1 - 1.6 8.4 7.6 17 5.1 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 ORY73443.1 - 1.7 8.9 7.0 4.4 7.6 0.6 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat PA PF02225.22 ORY73444.1 - 0.079 13.0 0.4 0.22 11.6 0.4 1.7 1 0 0 1 1 1 0 PA domain DUF4366 PF14283.6 ORY73444.1 - 0.081 13.0 2.9 9.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) DSHCT PF08148.12 ORY73444.1 - 0.15 11.7 0.4 0.37 10.5 0.4 1.7 1 0 0 1 1 1 0 DSHCT (NUC185) domain Rep_4 PF05797.11 ORY73444.1 - 0.18 10.9 0.5 0.34 10.0 0.5 1.4 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) TRL PF13146.6 ORY73445.1 - 0.18 12.1 0.0 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 TRL-like protein family Ceramidase PF05875.12 ORY73446.1 - 2.3e-81 273.1 9.2 2.7e-81 272.9 9.2 1.0 1 0 0 1 1 1 1 Ceramidase PPP4R2 PF09184.11 ORY73447.1 - 0.015 14.9 1.5 0.024 14.2 1.5 1.3 1 0 0 1 1 1 0 PPP4R2 RPN2_C PF18004.1 ORY73447.1 - 0.049 13.6 5.8 0.1 12.5 5.8 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PSK PF06404.12 ORY73447.1 - 0.51 11.4 5.0 0.18 12.9 2.1 1.7 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Btz PF09405.10 ORY73448.1 - 9.7e-06 25.9 8.9 9.7e-06 25.9 8.9 5.4 3 2 1 4 4 4 1 CASC3/Barentsz eIF4AIII binding F-box PF00646.33 ORY73449.1 - 8.7e-06 25.5 0.2 2e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY73449.1 - 1.4e-05 24.8 0.0 4.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY73449.1 - 0.019 14.9 0.0 0.072 13.0 0.0 2.0 2 0 0 2 2 2 0 F-box TauD PF02668.16 ORY73450.1 - 2.7e-48 165.1 0.0 3.3e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TAP_C PF03943.13 ORY73452.1 - 5.9e-14 51.4 0.4 1.1e-13 50.5 0.4 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 ORY73452.1 - 0.0041 17.5 3.0 0.029 14.8 2.6 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) NTF2 PF02136.20 ORY73452.1 - 0.024 15.2 0.0 0.11 13.0 0.0 2.1 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain LRR_9 PF14580.6 ORY73452.1 - 0.052 13.0 0.2 0.25 10.8 0.2 2.0 1 1 0 1 1 1 0 Leucine-rich repeat DLEU7 PF15760.5 ORY73453.1 - 0.0038 16.7 1.2 0.0098 15.4 0.0 2.0 1 1 1 2 2 2 1 Leukemia-associated protein 7 GntR PF00392.21 ORY73453.1 - 0.099 12.3 0.0 0.3 10.8 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Lipase_GDSL_2 PF13472.6 ORY73455.1 - 1.5e-09 38.5 0.0 1.9e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY73455.1 - 7.6e-07 29.3 0.0 1.3e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GRP PF07172.11 ORY73456.1 - 0.36 11.5 38.4 3.1 8.5 26.1 2.3 2 0 0 2 2 2 0 Glycine rich protein family DUF4451 PF14616.6 ORY73457.1 - 2.6e-30 105.1 0.0 3.9e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) YTH PF04146.15 ORY73582.1 - 2.1e-54 183.9 0.0 4.1e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 ORY73582.1 - 0.027 14.3 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ PF12752.7 ORY73583.1 - 0.05 14.4 1.2 0.05 14.4 1.2 3.3 4 0 0 4 4 4 0 SUZ domain Sas10 PF09368.10 ORY73586.1 - 9.1e-25 86.9 4.9 9.1e-25 86.9 4.9 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 ORY73586.1 - 0.026 15.1 0.2 0.12 13.1 0.2 2.2 1 0 0 1 1 1 0 Sas10/Utp3/C1D family TMEM51 PF15345.6 ORY73586.1 - 2.9 7.7 6.3 9.9 5.9 6.3 1.9 1 0 0 1 1 1 0 Transmembrane protein 51 Fcf2 PF08698.11 ORY73587.1 - 4.3e-32 110.4 0.1 1.2e-31 108.9 0.0 1.8 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing BUD22 PF09073.10 ORY73587.1 - 0.00089 18.7 19.5 0.0015 18.0 19.5 1.3 1 0 0 1 1 1 1 BUD22 Mpp10 PF04006.12 ORY73587.1 - 0.0046 15.5 7.3 0.0061 15.1 7.3 1.2 1 0 0 1 1 1 1 Mpp10 protein NOA36 PF06524.12 ORY73587.1 - 1.6 8.0 23.8 0.88 8.8 13.1 2.2 2 0 0 2 2 2 0 NOA36 protein EBP50_C PF09007.11 ORY73587.1 - 1.9 9.5 13.3 4 8.4 8.1 3.0 3 0 0 3 3 3 0 EBP50, C-terminal Abhydrolase_1 PF00561.20 ORY73588.1 - 3.4e-21 76.0 0.0 2e-15 57.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY73588.1 - 1.6e-18 66.9 0.1 4.6e-18 65.4 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY73588.1 - 2.4e-14 54.5 0.0 3.2e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.9 ORY73588.1 - 9.9e-06 24.9 0.1 0.071 12.2 0.1 2.2 2 0 0 2 2 2 2 Abhydrolase domain containing 18 Peptidase_S15 PF02129.18 ORY73588.1 - 0.00084 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 ORY73588.1 - 0.0016 18.1 0.1 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 ORY73588.1 - 0.0037 16.0 0.7 1.1 7.9 0.1 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.18 ORY73588.1 - 0.0062 16.1 0.0 0.27 10.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 ORY73588.1 - 0.014 15.1 0.4 0.073 12.7 0.3 2.2 2 1 0 3 3 3 0 Putative esterase Lipase_2 PF01674.18 ORY73588.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Thioesterase PF00975.20 ORY73588.1 - 0.034 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF1100 PF06500.11 ORY73588.1 - 0.04 12.7 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.13 ORY73588.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold GUCT PF08152.12 ORY73588.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 GUCT (NUC152) domain CinA PF02464.17 ORY73589.1 - 1.8e-29 102.3 0.2 2.1e-29 102.1 0.2 1.1 1 0 0 1 1 1 1 Competence-damaged protein Glyoxal_oxid_N PF07250.11 ORY73590.1 - 8.7e-25 87.3 0.4 9.2e-20 70.9 0.5 3.4 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY73590.1 - 4.9e-20 71.6 0.0 1.1e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 ORY73590.1 - 0.02 14.9 0.0 12 6.1 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.6 ORY73590.1 - 0.041 13.9 0.1 6.2 6.9 0.0 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain Pmp3 PF01679.17 ORY73591.1 - 1.9e-20 72.8 7.4 1.9e-20 72.8 7.4 1.7 2 0 0 2 2 2 1 Proteolipid membrane potential modulator DUF872 PF05915.12 ORY73591.1 - 0.061 13.5 0.0 0.068 13.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF2828 PF11443.8 ORY73592.1 - 9.4e-30 103.3 0.0 1.1e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DUF3621 PF12285.8 ORY73592.1 - 0.06 13.7 1.5 4.2 7.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3621) Glyoxal_oxid_N PF07250.11 ORY73593.1 - 7.8e-31 107.1 0.0 1.5e-23 83.2 0.0 3.5 4 1 0 4 4 4 2 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY73593.1 - 1e-21 77.0 0.0 2.3e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 ORY73593.1 - 0.11 12.5 0.2 2.5 8.2 0.0 3.5 3 0 0 3 3 3 0 Galactose oxidase, central domain Man-6-P_recep PF02157.15 ORY73593.1 - 0.25 10.4 0.0 0.46 9.5 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor POP1 PF06978.11 ORY73594.1 - 5.5e-46 157.1 22.6 3.6e-23 82.7 4.9 2.3 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 ORY73594.1 - 9.7e-27 93.2 0.1 2.6e-26 91.8 0.1 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain Tex_N PF09371.10 ORY73595.1 - 0.031 13.9 0.7 0.042 13.5 0.7 1.1 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Syntaxin_2 PF14523.6 ORY73595.1 - 0.04 14.3 0.3 0.072 13.5 0.3 1.5 1 1 0 1 1 1 0 Syntaxin-like protein NOG1_N PF17835.1 ORY73595.1 - 0.089 12.8 0.1 0.13 12.3 0.1 1.1 1 0 0 1 1 1 0 NOG1 N-terminal helical domain BLOC1_2 PF10046.9 ORY73595.1 - 0.1 12.9 1.0 0.18 12.1 0.4 1.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cortex-I_coil PF09304.10 ORY73595.1 - 0.11 12.7 3.7 0.16 12.2 3.7 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF1192 PF06698.11 ORY73595.1 - 0.13 12.3 0.8 0.36 10.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SnoaL_4 PF13577.6 ORY73597.1 - 4.3e-05 23.6 0.1 6.7e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ORY73597.1 - 0.0006 20.4 0.5 0.0012 19.5 0.3 1.7 1 1 0 1 1 1 1 SnoaL-like domain Tam41_Mmp37 PF09139.11 ORY73598.1 - 3.6e-82 276.4 0.0 1.5e-41 142.9 0.0 3.1 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial O-FucT PF10250.9 ORY73599.1 - 1.3e-08 35.0 0.2 9.8e-06 25.5 0.0 3.2 4 0 0 4 4 4 2 GDP-fucose protein O-fucosyltransferase Metallophos PF00149.28 ORY73600.1 - 8e-05 23.2 0.0 0.012 16.1 0.0 2.8 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Apt1 PF10351.9 ORY73600.1 - 1.7 7.4 3.5 2.8 6.7 3.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 ORY73601.1 - 2.5e-27 95.9 0.0 3.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY73601.1 - 9e-11 41.5 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY73601.1 - 2.2e-08 33.3 0.0 2.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY73601.1 - 0.039 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SET PF00856.28 ORY73603.1 - 3.1e-08 34.2 0.0 7.9e-08 32.9 0.0 1.7 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 ORY73603.1 - 6.1e-08 32.2 2.2 0.028 14.2 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY73603.1 - 6.7e-06 25.8 5.4 0.047 13.8 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY73603.1 - 0.029 14.6 5.4 1.1 9.5 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat PilJ PF13675.6 ORY73603.1 - 0.04 13.9 0.0 0.15 12.1 0.0 1.9 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term PGC7_Stella PF15549.6 ORY73603.1 - 0.06 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain TPR_19 PF14559.6 ORY73603.1 - 0.15 12.6 8.9 0.33 11.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY73603.1 - 7.7 7.6 15.2 0.64 11.0 1.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2828 PF11443.8 ORY73605.1 - 2.1e-182 607.5 0.0 2.5e-182 607.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) VWA_2 PF13519.6 ORY73605.1 - 0.14 12.8 0.0 0.44 11.2 0.0 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain Lipase_GDSL PF00657.22 ORY73606.1 - 2.7e-11 43.8 0.0 3.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY73606.1 - 7.3e-07 29.8 0.8 1.8e-06 28.5 0.8 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Casc1_N PF15927.5 ORY73606.1 - 0.038 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus YchF-GTPase_C PF06071.13 ORY73607.1 - 6.8e-35 119.1 0.4 3.6e-34 116.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY73607.1 - 9.1e-19 67.6 0.0 1.3e-17 63.9 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY73607.1 - 1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 ORY73607.1 - 0.13 12.8 0.1 1.9 9.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain SCP2 PF02036.17 ORY73608.1 - 5.8e-17 62.0 0.2 8.9e-17 61.4 0.2 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ORY73608.1 - 0.00029 21.1 0.0 0.00049 20.4 0.0 1.5 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 ORY73608.1 - 0.034 14.6 0.0 0.067 13.6 0.0 1.5 1 1 0 1 1 1 0 Sterol carrier protein domain Ydr279_N PF17745.1 ORY73608.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.6 1 1 0 2 2 2 0 Ydr279p protein triple barrel domain FGF PF00167.18 ORY73608.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Fibroblast growth factor KleE PF17394.2 ORY73609.1 - 0.067 13.4 1.0 0.19 11.9 1.0 1.8 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein DUF2275 PF10039.9 ORY73609.1 - 0.095 12.8 0.3 5.6 7.0 0.1 2.3 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) Internalin_N PF12354.8 ORY73609.1 - 0.18 11.9 0.4 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal ECF_trnsprt PF12822.7 ORY73609.1 - 0.29 11.2 17.0 0.27 11.3 15.2 1.7 1 1 0 1 1 1 0 ECF transporter, substrate-specific component Oxidored_q2 PF00420.24 ORY73609.1 - 5.1 6.8 8.3 8.5 6.1 0.0 3.1 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RRM_1 PF00076.22 ORY73610.1 - 3.6e-41 138.8 1.0 1e-13 50.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY73610.1 - 2.2e-09 37.1 0.0 0.0084 15.9 0.0 3.7 3 0 0 3 3 3 3 Occluded RNA-recognition motif NRDE-2 PF08424.10 ORY73610.1 - 0.00038 19.7 1.1 0.63 9.1 0.0 3.6 2 1 2 4 4 4 3 NRDE-2, necessary for RNA interference RRM_7 PF16367.5 ORY73610.1 - 0.0015 18.6 0.0 1.6 8.9 0.0 3.7 3 1 0 3 3 3 1 RNA recognition motif DUF3376 PF11856.8 ORY73610.1 - 0.0048 16.0 1.3 0.0082 15.2 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) RRM_3 PF08777.11 ORY73610.1 - 0.0092 16.0 0.8 1.7 8.7 0.0 4.2 5 0 0 5 5 5 1 RNA binding motif RNA_bind PF08675.11 ORY73610.1 - 0.096 12.7 0.1 5.6 7.1 0.1 3.3 3 0 0 3 3 3 0 RNA binding domain DUF4080 PF13311.6 ORY73610.1 - 0.11 12.6 0.4 0.22 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) TPR_14 PF13428.6 ORY73610.1 - 7.9 7.6 7.7 62 4.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 ORY73612.1 - 2.3e-65 220.9 0.0 3.1e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY73612.1 - 1.7e-31 109.7 0.0 3.1e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY73612.1 - 0.022 15.0 0.2 0.022 15.0 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY73612.1 - 0.031 13.9 0.4 0.073 12.6 0.4 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY73612.1 - 0.037 13.1 0.1 0.093 11.8 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 ORY73612.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 ORY73612.1 - 0.16 11.2 0.1 0.98 8.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 ORY73613.1 - 3.2e-62 210.6 0.3 4.2e-62 210.2 0.3 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY73613.1 - 5.5e-34 117.7 0.0 1e-33 116.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY73613.1 - 0.00049 20.3 0.2 0.0012 19.0 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 ORY73613.1 - 0.0015 18.8 0.2 0.004 17.4 0.2 1.7 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 ORY73613.1 - 0.0029 16.9 0.1 0.016 14.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY73613.1 - 0.0039 16.8 0.4 0.0039 16.8 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY73613.1 - 0.0045 16.1 0.1 0.0088 15.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY73613.1 - 0.0067 15.6 0.3 0.022 13.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY73613.1 - 0.014 14.7 0.2 0.035 13.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY73613.1 - 0.082 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ORY73613.1 - 0.11 11.1 0.7 0.17 10.6 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 ORY73613.1 - 0.12 12.9 0.1 0.28 11.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 ORY73614.1 - 1.4e-60 205.1 0.0 1.9e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY73614.1 - 2.2e-29 102.8 0.0 3.4e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 ORY73614.1 - 0.00037 20.2 0.9 0.00085 19.0 0.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY73614.1 - 0.0012 18.0 0.2 0.0017 17.4 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ORY73614.1 - 0.0015 18.7 0.5 0.0037 17.5 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY73614.1 - 0.0021 17.2 0.4 0.0048 16.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY73614.1 - 0.0038 16.5 0.1 0.033 13.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY73614.1 - 0.0064 15.8 0.1 0.014 14.7 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY73614.1 - 0.031 13.5 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 ORY73614.1 - 0.056 12.1 0.1 0.085 11.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ORY73614.1 - 0.11 13.0 0.4 0.4 11.3 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY73614.1 - 0.16 10.8 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 ORY73614.1 - 0.21 10.6 0.1 0.32 10.0 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amidohydro_1 PF01979.20 ORY73615.1 - 3.4e-66 223.9 1.2 5.8e-66 223.1 1.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY73615.1 - 4.6e-54 181.9 2.5 9.9e-54 180.8 2.5 1.6 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ORY73615.1 - 4e-39 132.6 0.3 1.7e-38 130.6 0.1 2.1 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 ORY73615.1 - 2.8e-38 130.2 0.5 7e-38 128.9 0.1 2.0 2 0 0 2 2 2 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ORY73615.1 - 2e-05 24.3 1.2 5.3e-05 22.9 0.2 2.1 1 1 0 2 2 2 1 Amidohydrolase family PhyH PF05721.13 ORY73616.1 - 6.3e-50 170.4 0.0 7.5e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Orf78 PF06024.12 ORY73617.1 - 0.12 12.7 0.1 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 Orf78 (ac78) Tmemb_9 PF05434.11 ORY73617.1 - 0.23 11.3 0.8 0.56 10.1 0.8 1.6 1 0 0 1 1 1 0 TMEM9 zf-RING_5 PF14634.6 ORY73618.1 - 1.4e-06 28.1 0.3 2.6e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY73618.1 - 0.0014 18.6 0.3 0.003 17.6 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY73618.1 - 0.0032 17.6 1.0 0.012 15.7 1.0 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY73618.1 - 0.015 15.2 0.1 0.037 13.9 0.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY73618.1 - 0.041 14.2 0.4 0.079 13.3 0.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 ORY73618.1 - 0.32 10.9 1.3 0.79 9.6 1.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORY73618.1 - 0.55 10.4 1.8 1.3 9.2 1.8 1.5 1 1 0 1 1 1 0 zinc RING finger of MSL2 DUF3482 PF11981.8 ORY73618.1 - 7.7 5.8 8.5 17 4.7 8.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) FAD_binding_3 PF01494.19 ORY73619.1 - 1.6e-10 40.8 0.0 3.3e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY73619.1 - 0.015 14.5 0.9 3.6 6.7 0.0 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY73619.1 - 0.076 13.0 0.5 15 5.6 0.2 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding His_Phos_1 PF00300.22 ORY73620.1 - 6.7e-13 48.8 0.1 3.3e-11 43.3 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FmdA_AmdA PF03069.15 ORY73620.1 - 0.16 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family His_Phos_1 PF00300.22 ORY73621.1 - 1.5e-16 60.7 0.5 2.9e-16 59.8 0.5 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) EOS1 PF12326.8 ORY73622.1 - 1.9e-40 138.6 13.4 4.1e-39 134.3 13.4 2.4 1 1 0 1 1 1 1 N-glycosylation protein Galactosyl_T PF01762.21 ORY73622.1 - 1.5e-20 73.8 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Gly_transf_sug PF04488.15 ORY73622.1 - 3e-07 31.0 0.0 7.6e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 ORY73622.1 - 0.00048 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Myb_DNA-bind_6 PF13921.6 ORY73623.1 - 5.3e-06 26.6 0.7 0.0006 20.0 0.1 2.5 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY73623.1 - 1.6e-05 25.0 0.6 0.071 13.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain NAD_binding_10 PF13460.6 ORY73624.1 - 4.7e-13 49.4 0.0 1e-12 48.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Voldacs PF03517.13 ORY73625.1 - 5.8e-24 84.8 0.0 1.5e-23 83.5 0.0 1.7 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling ELO PF01151.18 ORY73626.1 - 1.2e-60 205.1 11.2 1.5e-60 204.8 11.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Citrate_synt PF00285.21 ORY73627.1 - 1.5e-89 300.6 0.0 1.9e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF3500 PF12006.8 ORY73628.1 - 1.3e-87 294.0 0.0 1.5e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Fungal_trans PF04082.18 ORY73629.1 - 1.5e-06 27.4 0.3 3.6e-06 26.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY73629.1 - 0.0037 17.3 10.4 0.0061 16.7 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.18 ORY73631.1 - 1.6e-53 181.6 0.0 2e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.19 ORY73632.1 - 5.7e-12 45.6 0.1 3.7e-11 42.9 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain PBC PF03792.13 ORY73632.1 - 0.24 11.1 0.0 0.4 10.4 0.0 1.2 1 0 0 1 1 1 0 PBC domain MFS_1 PF07690.16 ORY73633.1 - 2.4e-33 115.6 29.9 2.4e-33 115.6 29.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY73633.1 - 7e-16 58.1 7.2 7e-16 58.1 7.2 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter Ca_hom_mod PF14798.6 ORY73633.1 - 0.043 12.9 0.5 0.44 9.6 0.2 2.1 2 0 0 2 2 2 0 Calcium homeostasis modulator Chlam_OMP PF01308.17 ORY73633.1 - 0.086 11.6 0.0 0.66 8.7 0.0 2.0 2 0 0 2 2 2 0 Chlamydia major outer membrane protein Abhydrolase_1 PF00561.20 ORY73634.1 - 1e-24 87.6 0.0 1.5e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY73634.1 - 3.7e-17 63.7 0.0 1.3e-16 61.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY73634.1 - 3.2e-14 52.8 0.0 4.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY73634.1 - 8e-09 35.6 0.1 2.4e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 PGAP1-like protein Thioesterase PF00975.20 ORY73634.1 - 2.7e-08 34.2 0.0 3.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 ORY73634.1 - 0.00014 21.5 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 ORY73634.1 - 0.00034 20.5 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 ORY73634.1 - 0.0005 20.0 0.0 0.00058 19.8 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 ORY73634.1 - 0.00084 18.3 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORY73634.1 - 0.0026 16.8 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_5 PF12695.7 ORY73634.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 ORY73634.1 - 0.017 14.7 0.0 0.037 13.5 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.25 ORY73634.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.20 ORY73634.1 - 0.028 14.0 0.2 0.061 13.0 0.2 1.6 1 1 0 1 1 1 0 Putative esterase Thioredoxin_12 PF18400.1 ORY73634.1 - 0.039 13.8 0.0 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain BAAT_C PF08840.11 ORY73634.1 - 0.042 13.8 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3530 PF12048.8 ORY73634.1 - 0.085 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) LCAT PF02450.15 ORY73634.1 - 0.089 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2974 PF11187.8 ORY73634.1 - 0.21 11.1 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) bZIP_1 PF00170.21 ORY73635.1 - 0.00026 21.0 2.9 0.00042 20.3 2.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY73635.1 - 0.072 13.2 3.5 0.13 12.4 3.5 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Lzipper-MIP1 PF14389.6 ORY73635.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Nnf1 PF03980.14 ORY73635.1 - 0.3 11.5 2.1 0.55 10.6 2.1 1.3 1 0 0 1 1 1 0 Nnf1 Myb_DNA-bind_6 PF13921.6 ORY73636.1 - 0.0014 18.8 0.1 0.35 11.1 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain adh_short PF00106.25 ORY73638.1 - 1.2e-08 34.7 0.0 1.5e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORY73638.1 - 0.0019 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY73638.1 - 0.063 13.5 0.0 0.099 12.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UBX PF00789.20 ORY73639.1 - 7.6e-11 42.1 0.1 2.3e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 UBX domain YopE_N PF09020.10 ORY73639.1 - 3.1 8.1 5.6 1.5 9.1 0.0 2.2 1 1 1 2 2 2 0 YopE, N terminal UvrD-helicase PF00580.21 ORY73640.1 - 3.8e-67 227.0 0.0 6.7e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 ORY73640.1 - 7.2e-57 193.3 0.0 5.2e-30 105.0 0.0 2.5 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ORY73640.1 - 1.1e-28 100.4 0.0 2.2e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ORY73640.1 - 1.2e-10 41.0 0.1 3.9e-10 39.4 0.1 1.9 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ORY73640.1 - 8.2e-08 32.2 0.4 3.5e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ORY73640.1 - 2.8e-07 30.5 0.1 0.0039 17.0 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 ORY73640.1 - 0.023 14.5 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 ORY73640.1 - 0.048 13.3 0.1 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 ORY73641.1 - 4.7e-11 42.7 0.0 0.0056 16.9 0.0 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY73641.1 - 4.9e-11 42.7 0.0 0.0081 16.4 0.0 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY73641.1 - 9.7e-06 25.9 0.2 0.0055 17.1 0.0 3.1 3 0 0 3 3 3 2 Myb/SANT-like DNA-binding domain HTH_32 PF13565.6 ORY73641.1 - 0.096 13.3 4.9 3.8 8.2 1.3 3.1 2 1 1 3 3 3 0 Homeodomain-like domain NAD_binding_10 PF13460.6 ORY73642.1 - 6.9e-16 58.7 0.0 1.3e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY73642.1 - 0.12 11.9 0.3 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 NmrA-like family Myb_DNA-bind_6 PF13921.6 ORY73643.1 - 4.1e-07 30.1 0.2 0.00055 20.1 0.0 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY73643.1 - 8e-07 29.2 0.1 0.0017 18.5 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain DAO PF01266.24 ORY73644.1 - 1.7e-45 156.2 2.6 1.9e-45 156.0 2.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY73644.1 - 6.3e-05 23.0 0.4 0.0056 16.7 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY73644.1 - 0.00032 20.9 0.6 0.00086 19.5 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY73644.1 - 0.019 14.2 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ORY73644.1 - 0.051 12.9 2.0 0.12 11.7 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY73644.1 - 0.094 11.9 0.5 0.19 10.9 0.4 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY73644.1 - 0.15 11.3 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase C2 PF00168.30 ORY73645.1 - 1.5e-25 89.5 0.0 7.4e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 ORY73645.1 - 0.0009 18.7 0.1 1.6 8.2 0.0 2.5 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain Myb_DNA-binding PF00249.31 ORY73646.1 - 7e-09 35.7 2.0 5.1e-08 33.0 0.1 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY73646.1 - 3.2e-06 27.3 0.3 1.2e-05 25.4 0.3 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Anp1 PF03452.14 ORY73647.1 - 3.1e-67 226.8 0.0 4e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 ORY73647.1 - 0.0029 17.4 0.1 0.43 10.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 DIE2_ALG10 PF04922.12 ORY73648.1 - 3.2e-115 385.6 9.4 3.8e-115 385.3 9.4 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family MFS_1 PF07690.16 ORY73649.1 - 8.1e-25 87.5 38.7 8.1e-25 87.5 38.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily CPP1-like PF11833.8 ORY73649.1 - 0.93 9.1 4.5 0.71 9.5 0.2 2.8 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CrgA PF06781.12 ORY73649.1 - 1.4 9.0 6.0 7.8 6.6 0.3 2.7 2 0 0 2 2 2 0 Cell division protein CrgA P34-Arc PF04045.14 ORY73650.1 - 2.6e-108 361.2 0.0 3.3e-108 360.9 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Serinc PF03348.15 ORY73651.1 - 1.2e-153 512.1 0.8 2e-153 511.4 0.8 1.3 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF4482 PF14818.6 ORY73652.1 - 0.023 15.6 0.0 0.047 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) CBP PF12192.8 ORY73652.1 - 0.098 12.9 1.8 0.2 11.9 1.8 1.6 1 0 0 1 1 1 0 Fungal calcium binding protein TauD PF02668.16 ORY73653.1 - 5.8e-31 108.3 0.7 1.4e-30 107.0 0.7 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LTXXQ PF07813.12 ORY73653.1 - 0.2 12.4 0.1 5.6 7.7 0.0 2.5 3 0 0 3 3 3 0 LTXXQ motif family protein Phosphonate-bd PF12974.7 ORY73654.1 - 5.9e-08 32.6 0.1 2.3e-06 27.4 0.1 2.1 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 ORY73654.1 - 2e-06 27.9 0.1 7.3e-06 26.1 0.1 1.8 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 ORY73654.1 - 0.00035 20.1 0.1 0.00097 18.6 0.0 1.7 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_3 PF16868.5 ORY73654.1 - 0.00056 19.4 0.2 0.0013 18.2 0.2 1.6 1 1 0 1 1 1 1 NMT1-like family DivIVA PF05103.13 ORY73654.1 - 0.0071 16.4 0.1 0.038 14.1 0.0 1.9 1 1 1 2 2 2 1 DivIVA protein LysR_substrate PF03466.20 ORY73654.1 - 0.031 13.6 0.0 0.26 10.6 0.0 2.4 2 1 0 2 2 2 0 LysR substrate binding domain SBP_bac_11 PF13531.6 ORY73654.1 - 0.04 13.7 0.2 0.15 11.8 0.2 1.7 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein TRM PF02005.16 ORY73655.1 - 1e-108 363.9 0.0 1.4e-91 307.5 0.0 2.0 1 1 1 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase F-box-like PF12937.7 ORY73818.1 - 0.013 15.4 1.5 0.026 14.4 0.8 1.9 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 ORY73819.1 - 0.00068 19.5 0.2 0.0016 18.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like WW PF00397.26 ORY73820.1 - 1.7e-10 40.8 6.6 4.1e-10 39.6 6.6 1.7 1 0 0 1 1 1 1 WW domain Cation_efflux PF01545.21 ORY73821.1 - 5.9e-09 35.9 0.2 1.2e-08 34.9 0.1 1.5 1 1 0 1 1 1 1 Cation efflux family Med1 PF10744.9 ORY73823.1 - 2.8e-16 59.6 0.0 3.9e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Mitoc_L55 PF09776.9 ORY73823.1 - 0.1 12.4 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 APH PF01636.23 ORY73824.1 - 7e-10 39.2 0.0 9.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY73824.1 - 0.00031 20.4 0.0 0.00043 19.9 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Mob1_phocein PF03637.17 ORY73825.1 - 7.1e-22 78.2 0.0 1e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family SNAP PF14938.6 ORY73826.1 - 1.4e-105 352.7 16.6 1.6e-105 352.6 16.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 ORY73826.1 - 0.00048 20.6 7.7 28 5.6 0.2 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY73826.1 - 0.0017 18.6 10.5 0.33 11.3 0.0 4.1 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY73826.1 - 0.0031 17.5 11.9 2.9 8.2 0.6 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat Clathrin PF00637.20 ORY73826.1 - 0.047 13.6 0.1 0.43 10.4 0.0 2.4 1 1 0 2 2 2 0 Region in Clathrin and VPS Spatacsin_C PF14649.6 ORY73826.1 - 0.19 10.8 4.5 0.71 8.9 4.4 2.0 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_1 PF00515.28 ORY73826.1 - 0.78 9.7 11.4 5.7 6.9 0.1 5.2 4 2 2 6 6 6 0 Tetratricopeptide repeat MIT PF04212.18 ORY73826.1 - 2 8.6 12.4 1.7 8.8 0.1 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 ORY73826.1 - 7.5 6.8 10.2 4 7.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat UQ_con PF00179.26 ORY73827.1 - 6.3e-42 142.5 0.0 7.9e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 ORY73827.1 - 5.8e-07 29.2 0.1 2.6e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Fungal ubiquitin-associated domain ArfGap PF01412.18 ORY73829.1 - 5.9e-30 103.7 0.2 1.4e-29 102.5 0.2 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF2621 PF11084.8 ORY73829.1 - 0.043 13.8 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) ENTH PF01417.20 ORY73830.1 - 1.5e-44 151.0 0.1 2.3e-44 150.4 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ORY73830.1 - 0.0019 17.3 0.1 0.0026 16.8 0.1 1.2 1 0 0 1 1 1 1 ANTH domain DUF2441 PF10386.9 ORY73830.1 - 0.14 12.1 0.2 0.24 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) F-box-like PF12937.7 ORY73831.1 - 3.7e-06 26.7 0.9 1.7e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY73831.1 - 0.17 11.8 1.5 0.75 9.8 0.1 2.8 3 1 0 3 3 3 0 F-box domain ETF PF01012.21 ORY73833.1 - 2.9e-39 134.8 4.2 4.5e-39 134.2 4.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 ORY73833.1 - 7.2e-34 115.7 1.0 1.6e-33 114.5 1.0 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain HR1 PF02185.16 ORY73834.1 - 2.9e-09 36.9 8.4 4.4e-09 36.3 8.4 1.2 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 ORY73834.1 - 0.0018 18.5 1.6 0.0024 18.0 1.6 1.1 1 0 0 1 1 1 1 Up-regulated During Septation MraZ PF02381.18 ORY73834.1 - 0.14 12.2 0.5 0.61 10.1 0.1 2.0 2 0 0 2 2 2 0 MraZ protein, putative antitoxin-like RICTOR_N PF14664.6 ORY73835.1 - 1.1e-103 347.2 0.0 2e-103 346.3 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 ORY73835.1 - 4.9e-40 135.5 0.6 3.6e-35 119.9 0.1 5.3 5 0 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 ORY73835.1 - 2.3e-32 111.6 0.3 3.3e-31 107.9 0.1 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 ORY73835.1 - 3.3e-29 100.9 1.0 7.5e-27 93.4 0.1 4.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 ORY73835.1 - 0.017 15.5 13.0 12 6.4 0.1 6.9 8 0 0 8 8 8 0 HEAT repeats HEAT PF02985.22 ORY73835.1 - 0.059 13.6 10.1 4.3 7.9 0.1 6.0 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 ORY73835.1 - 0.076 13.5 6.7 2.3 8.8 0.0 5.1 6 0 0 6 6 6 0 HEAT-like repeat MyTH4 PF00784.17 ORY73835.1 - 0.096 13.2 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 MyTH4 domain NFACT-R_1 PF05670.13 ORY73836.1 - 2.2e-30 105.5 0.0 3.2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain Trm5_N PF18093.1 ORY73836.1 - 2.7 8.0 5.4 12 5.9 0.0 2.5 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Dynamin_N PF00350.23 ORY73837.1 - 8.2e-17 61.8 0.4 4.8e-16 59.3 0.0 2.5 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ORY73837.1 - 8.1e-12 45.2 0.0 8.7e-11 41.9 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY73837.1 - 2.9e-06 27.0 0.0 0.009 15.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY73837.1 - 0.003 17.5 0.1 3.8 7.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY73837.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 ORY73837.1 - 0.022 14.3 0.0 5.6 6.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 ORY73837.1 - 0.031 14.5 0.0 0.62 10.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 ORY73837.1 - 0.065 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 ORY73837.1 - 0.096 12.7 0.2 0.51 10.4 0.1 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.9 ORY73837.1 - 0.2 11.4 0.0 26 4.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TMF_TATA_bd PF12325.8 ORY73837.1 - 8.8 6.6 19.0 5.1 7.3 2.5 4.3 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding F-box-like PF12937.7 ORY73838.1 - 8.8e-05 22.3 0.9 0.00028 20.7 0.1 2.3 2 0 0 2 2 2 1 F-box-like Xan_ur_permease PF00860.20 ORY73839.1 - 4.9e-58 196.7 29.2 4.4e-40 137.6 12.7 2.1 2 0 0 2 2 2 2 Permease family Macoilin PF09726.9 ORY73841.1 - 0.0034 16.0 1.1 0.0047 15.6 1.1 1.1 1 0 0 1 1 1 1 Macoilin family Zn_clus PF00172.18 ORY73841.1 - 0.15 12.2 6.1 0.28 11.3 6.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 ORY73842.1 - 6.9e-18 64.7 8.4 0.0031 18.3 0.2 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Asparaginase PF00710.20 ORY73843.1 - 1e-46 158.9 3.9 1.6e-46 158.3 3.9 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORY73843.1 - 8.3e-21 74.3 1.4 2.1e-20 73.1 0.1 2.3 2 1 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain GPP34 PF05719.11 ORY73844.1 - 3.6e-64 216.6 0.1 5.3e-64 216.0 0.1 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Cpn60_TCP1 PF00118.24 ORY73845.1 - 1.5e-154 515.3 6.0 2.1e-154 514.8 6.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AA_permease PF00324.21 ORY73846.1 - 7.4e-127 423.8 33.3 8.3e-127 423.7 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY73846.1 - 7.4e-38 130.5 36.2 9.7e-38 130.1 36.2 1.2 1 0 0 1 1 1 1 Amino acid permease Phage_Gp23 PF10669.9 ORY73846.1 - 0.14 12.5 0.3 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Aldo_ket_red PF00248.21 ORY73847.1 - 7.2e-67 225.6 0.0 8.7e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexapep PF00132.24 ORY73848.1 - 5e-12 45.0 19.0 7.1e-07 28.7 4.4 5.0 3 2 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORY73848.1 - 1.4e-07 31.1 14.6 0.0005 19.8 5.0 4.4 3 1 2 5 5 5 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY73848.1 - 0.00013 21.0 0.7 0.00029 19.9 0.3 1.5 1 1 1 2 2 2 1 L-fucokinase Transket_pyr PF02779.24 ORY73850.1 - 1e-64 217.5 0.0 1.5e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ORY73850.1 - 6.5e-58 196.1 0.0 8.5e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 ORY73850.1 - 5.4e-51 172.3 0.0 9e-51 171.6 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 ORY73850.1 - 7.5e-17 60.6 0.7 1.8e-16 59.4 0.7 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus baeRF_family12 PF18856.1 ORY73850.1 - 0.031 14.8 0.2 0.094 13.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 Glyco_hydro_71 PF03659.14 ORY73851.1 - 2.5e-88 296.4 3.0 3.4e-88 296.0 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WD40 PF00400.32 ORY73852.1 - 6.3e-18 64.8 10.1 0.0038 18.0 0.2 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF2054 PF10218.9 ORY73853.1 - 0.0041 17.2 1.7 0.0058 16.7 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2054) Zn_clus PF00172.18 ORY73853.1 - 0.014 15.5 9.9 0.021 14.9 9.9 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain betaPIX_CC PF16523.5 ORY73853.1 - 0.074 12.9 0.3 0.13 12.1 0.3 1.3 1 0 0 1 1 1 0 betaPIX coiled coil FEZ PF07763.13 ORY73853.1 - 0.12 12.1 1.2 0.17 11.6 1.2 1.1 1 0 0 1 1 1 0 FEZ-like protein Lzipper-MIP1 PF14389.6 ORY73853.1 - 0.15 12.4 2.6 0.73 10.2 0.2 2.4 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Macoilin PF09726.9 ORY73853.1 - 0.16 10.5 1.4 0.2 10.2 1.4 1.1 1 0 0 1 1 1 0 Macoilin family Cg6151-P PF10233.9 ORY73854.1 - 0.63 10.4 9.7 1.8 8.9 7.1 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein CG6151-P Zn_clus PF00172.18 ORY73855.1 - 1.9e-05 24.7 10.4 3.3e-05 23.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI PF01437.25 ORY73855.1 - 0.047 14.2 1.2 0.047 14.2 1.2 2.0 2 0 0 2 2 2 0 Plexin repeat MGC-24 PF05283.11 ORY73855.1 - 3.8 7.9 6.0 0.87 10.0 1.8 2.2 2 1 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BRO1 PF03097.18 ORY73856.1 - 2.4e-118 395.3 0.1 1.8e-117 392.5 0.0 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY73856.1 - 6.7e-62 209.4 11.1 1.1e-61 208.7 10.4 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV TMPIT PF07851.13 ORY73856.1 - 0.92 8.7 2.7 1.8 7.7 0.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein LRR_4 PF12799.7 ORY73857.1 - 1.8e-22 79.0 25.8 3.3e-05 24.1 1.4 8.8 5 3 3 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY73857.1 - 4.6e-20 71.1 28.7 2.7e-09 36.6 3.8 7.0 7 0 0 7 7 7 4 Leucine rich repeat LRR_9 PF14580.6 ORY73857.1 - 3.9e-10 39.5 6.0 0.00088 18.8 0.4 4.1 2 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 ORY73857.1 - 0.00011 22.3 13.8 18 6.3 0.1 8.5 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY73857.1 - 3.3 8.0 18.0 7.8 6.8 0.2 7.2 9 0 0 9 9 9 0 Leucine Rich repeat DHHA2 PF02833.14 ORY73858.1 - 6.1e-16 58.9 0.0 1.6e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 ORY73858.1 - 1.2e-09 38.3 0.0 2.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 DHH family DUF3717 PF12512.8 ORY73858.1 - 0.082 12.8 0.8 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) Ank_5 PF13857.6 ORY73860.1 - 1.1e-10 41.5 0.2 3e-10 40.1 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TIG PF01833.24 ORY73860.1 - 3.6e-10 39.8 0.3 3.3e-08 33.5 0.1 2.6 2 0 0 2 2 2 1 IPT/TIG domain Ank_4 PF13637.6 ORY73860.1 - 2.2e-09 37.6 0.2 2e-07 31.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY73860.1 - 1.4e-08 35.2 0.0 3.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY73860.1 - 2.2e-07 30.6 0.3 0.00089 19.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 ORY73860.1 - 6e-05 23.3 0.7 0.0028 18.0 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeat YL1 PF05764.13 ORY73860.1 - 0.0078 16.4 5.8 0.0078 16.4 5.8 3.8 3 2 0 3 3 3 1 YL1 nuclear protein Nop14 PF04147.12 ORY73860.1 - 1.1 7.3 9.2 2.7 6.1 9.2 1.5 1 0 0 1 1 1 0 Nop14-like family RCC1 PF00415.18 ORY73861.1 - 2.3e-52 175.4 13.3 9e-12 45.4 0.0 8.6 8 1 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY73861.1 - 2.8e-31 106.6 34.1 2.4e-07 30.3 0.3 7.7 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat FSH1 PF03959.13 ORY73865.1 - 5.1e-28 98.2 0.0 6.6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FSH1 PF03959.13 ORY73866.1 - 9.2e-45 152.9 0.0 1.1e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORY73866.1 - 0.014 15.2 0.0 2.2 8.0 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase NIF PF03031.18 ORY73867.1 - 4.7e-14 52.4 0.0 1.9e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Ribosomal_S10 PF00338.22 ORY73870.1 - 5.8e-27 93.8 0.5 6.8e-27 93.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e AAA_2 PF07724.14 ORY73871.1 - 9.8e-40 136.5 0.0 1.5e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 ORY73871.1 - 1.2e-13 51.6 0.0 6.4e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 ORY73871.1 - 1.7e-10 40.8 0.0 3.7e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 ORY73871.1 - 0.00029 20.8 0.0 0.001 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY73871.1 - 0.00073 19.8 0.1 0.0031 17.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY73871.1 - 0.00075 18.9 0.1 0.077 12.4 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORY73871.1 - 0.0011 18.7 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 ORY73871.1 - 0.011 15.9 0.0 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORY73871.1 - 0.011 15.5 0.0 0.028 14.1 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 ORY73871.1 - 0.021 15.4 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 ORY73871.1 - 0.026 14.9 1.8 0.079 13.3 0.1 2.5 2 1 0 3 3 3 0 AAA ATPase domain AAA_7 PF12775.7 ORY73871.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORY73871.1 - 0.051 13.3 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY73871.1 - 0.07 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 ORY73871.1 - 0.15 11.2 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain T2SSE PF00437.20 ORY73871.1 - 0.18 10.8 0.0 0.4 9.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein COG5 PF10392.9 ORY73872.1 - 1.8e-22 79.9 0.5 3.5e-21 75.8 0.0 3.3 2 1 0 2 2 2 1 Golgi transport complex subunit 5 COG2 PF06148.11 ORY73872.1 - 0.022 14.9 1.8 0.28 11.3 0.1 3.5 5 0 0 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 ORY73872.1 - 0.068 13.2 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 ORY73872.1 - 0.12 12.5 3.3 7.2 6.6 0.1 3.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus LexA_DNA_bind PF01726.16 ORY73873.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 LexA DNA binding domain Spuma_A9PTase PF03539.14 ORY73873.1 - 0.064 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Pkinase PF00069.25 ORY73875.1 - 6.6e-72 242.0 0.0 8.2e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY73875.1 - 1.8e-31 109.4 0.0 2.4e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY73875.1 - 4.5e-15 56.1 3.7 1.2e-14 54.7 3.7 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORY73875.1 - 6.1e-06 25.4 0.1 8.9e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY73875.1 - 0.0034 17.0 0.0 0.73 9.4 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 C2 PF00168.30 ORY73875.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 C2 domain Pkinase PF00069.25 ORY73876.1 - 1.7e-70 237.4 0.0 2.2e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY73876.1 - 1.1e-32 113.4 0.0 1.4e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY73876.1 - 2e-10 41.2 0.3 4.4e-10 40.1 0.3 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORY73876.1 - 8.9e-06 24.9 0.1 1.4e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY73876.1 - 2.2e-05 23.9 0.0 5.9e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORY73876.1 - 0.00091 18.9 0.1 0.85 9.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY73876.1 - 0.009 16.0 0.0 0.023 14.6 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY73876.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nas2_N PF18265.1 ORY73877.1 - 6.6e-23 80.4 0.1 1.1e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ PF00595.24 ORY73877.1 - 8.9e-06 26.0 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 ORY73877.1 - 1.9e-05 24.4 0.1 3.7e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 ORY73877.1 - 0.0021 18.4 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 ORY73877.1 - 0.0035 17.6 0.0 0.0069 16.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain RRM_1 PF00076.22 ORY73878.1 - 3.1e-06 26.9 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY73878.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM PF05172.13 ORY73878.1 - 0.08 12.9 0.1 0.91 9.5 0.1 2.4 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 ORY73878.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY73878.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif TFIID_20kDa PF03847.13 ORY73879.1 - 1.1e-30 106.0 1.3 1.4e-30 105.6 1.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 ORY73879.1 - 2.1e-05 24.7 0.1 4.1e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY73879.1 - 0.00012 22.5 0.1 0.00018 21.9 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 ORY73879.1 - 0.03 14.4 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CCDC-167 PF15188.6 ORY73880.1 - 0.077 13.3 0.3 0.077 13.3 0.3 2.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4484 PF14831.6 ORY73880.1 - 0.41 10.7 6.5 0.64 10.0 6.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Mit_KHE1 PF10173.9 ORY73880.1 - 1.6 8.7 7.8 2.6 8.1 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TERB2 PF15101.6 ORY73880.1 - 6.4 6.8 14.9 12 5.8 14.9 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 GFO_IDH_MocA PF01408.22 ORY74032.1 - 2.3e-10 41.4 0.5 8.9e-10 39.4 0.5 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Cellulase PF00150.18 ORY74032.1 - 0.096 12.1 0.3 0.24 10.8 0.0 1.7 1 1 1 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DNA_pol_B_thumb PF14791.6 ORY74034.1 - 5.1e-18 65.0 0.0 1.1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 ORY74034.1 - 5e-11 42.8 0.0 1.1e-10 41.7 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 ORY74034.1 - 9.3e-11 41.4 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 ORY74034.1 - 6.5e-05 23.5 0.0 0.0013 19.3 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_8 PF14716.6 ORY74034.1 - 0.00014 22.2 0.1 0.0022 18.3 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 ORY74034.1 - 0.00036 20.8 0.0 0.00069 19.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.8 ORY74034.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus Histone PF00125.24 ORY74035.1 - 1.7e-51 174.0 3.5 1.9e-51 173.8 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY74035.1 - 5.1e-05 23.6 0.1 7.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY74035.1 - 8e-05 22.7 0.1 0.00016 21.8 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY74035.1 - 0.00027 21.6 1.1 0.00032 21.3 1.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY74035.1 - 0.00062 20.0 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY74035.1 - 0.016 15.3 0.3 0.024 14.7 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY74035.1 - 0.059 13.4 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T_C PF15511.6 ORY74036.1 - 2.5e-07 30.8 0.1 3e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY74036.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY74036.1 - 0.0002 21.7 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY74036.1 - 0.0013 19.1 0.1 0.0015 18.9 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY74036.1 - 0.0014 18.8 0.1 0.0029 17.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY74036.1 - 0.099 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit LRR_8 PF13855.6 ORY74037.1 - 2.1 8.2 5.7 1.3 8.9 0.6 3.1 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 ORY74037.1 - 3.6 8.1 9.7 3.9 8.0 0.5 4.4 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) EamA PF00892.20 ORY74038.1 - 1.8e-05 25.0 2.7 1.8e-05 25.0 2.7 3.6 4 1 0 4 4 4 2 EamA-like transporter family DUF202 PF02656.15 ORY74038.1 - 4 8.0 17.6 9.9 6.7 2.1 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) RRM_1 PF00076.22 ORY74039.1 - 1.7e-06 27.7 0.0 0.063 13.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 ORY74040.1 - 0.022 14.6 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B_thumb PF14791.6 ORY74041.1 - 8.7e-20 70.7 0.0 1e-18 67.3 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 ORY74041.1 - 1.5e-18 67.0 0.1 4.1e-18 65.6 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 ORY74041.1 - 2.2e-06 27.9 0.1 1.4e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 ORY74041.1 - 1.5e-05 25.2 0.0 0.00011 22.4 0.0 2.2 1 1 1 2 2 2 1 Nucleotidyltransferase domain HHH PF00633.23 ORY74041.1 - 0.017 15.0 0.0 0.055 13.4 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 ORY74041.1 - 0.022 14.6 0.0 0.067 13.0 0.0 1.9 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 ORY74041.1 - 0.059 14.0 0.1 0.17 12.5 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix domain GlnD_UR_UTase PF08335.11 ORY74041.1 - 0.076 13.1 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase DUF1771 PF08590.10 ORY74042.1 - 6.6e-13 48.8 1.8 1.7e-12 47.5 1.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH_4 PF18044.1 ORY74042.1 - 0.0017 18.1 13.1 0.0095 15.7 1.8 3.2 2 1 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY74042.1 - 0.0026 17.8 13.7 0.1 12.7 4.0 3.1 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 ORY74042.1 - 0.0027 18.4 4.5 0.0047 17.6 0.4 2.4 1 1 1 2 2 2 1 Torus domain HBS1_N PF08938.10 ORY74042.1 - 0.0072 16.6 0.1 0.033 14.5 0.0 2.2 2 0 0 2 2 2 1 HBS1 N-terminus zf-CCCH PF00642.24 ORY74042.1 - 0.011 15.6 7.6 0.29 11.1 0.8 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.21 ORY74042.1 - 0.096 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Smr domain zf-CCCH_3 PF15663.5 ORY74042.1 - 0.21 11.8 4.5 3.4 7.9 0.3 2.4 1 1 1 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORY74042.1 - 4.7 7.8 11.4 2.4 8.8 1.8 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF1764 PF08576.10 ORY74043.1 - 1.1e-23 83.9 6.3 1.5e-20 73.9 0.4 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) TMEM214 PF10151.9 ORY74043.1 - 4.9 5.5 4.7 5.9 5.2 4.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MBOAT_2 PF13813.6 ORY74044.1 - 1.9e-18 66.5 8.2 3.6e-18 65.6 3.9 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PRK PF00485.18 ORY74045.1 - 2.2e-48 164.6 0.0 3e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 ORY74045.1 - 6.2e-43 146.6 0.0 1.8e-42 145.1 0.0 1.8 2 1 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 ORY74045.1 - 2.3e-05 25.0 0.0 4.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 ORY74045.1 - 0.0027 17.4 0.7 0.012 15.2 0.7 1.9 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 ORY74045.1 - 0.0031 17.7 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 ORY74045.1 - 0.011 15.6 0.1 0.033 14.0 0.1 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 ORY74045.1 - 0.032 14.6 0.0 0.32 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 ORY74045.1 - 0.044 14.2 0.3 4.3 7.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY74045.1 - 0.13 11.6 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 ORY74045.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 ORY74046.1 - 2.6e-16 59.2 0.0 6e-16 58.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY74046.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY74046.1 - 0.0086 16.2 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Dioxygenase_C PF00775.21 ORY74047.1 - 4.2e-47 159.9 0.0 5.5e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ORY74047.1 - 3.3e-21 74.9 0.0 5.1e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ORY74047.1 - 0.0023 18.2 0.0 0.0096 16.2 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.18 ORY74048.1 - 1.9e-16 59.9 0.0 3.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY74048.1 - 1.3e-08 34.8 11.2 2.2e-08 34.1 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACC_central PF08326.12 ORY74050.1 - 5e-249 828.4 0.0 6.3e-249 828.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORY74050.1 - 1.2e-169 565.1 0.0 1.6e-169 564.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORY74050.1 - 7.5e-53 179.2 0.0 1.5e-52 178.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY74050.1 - 2.5e-28 98.8 0.1 5.5e-28 97.7 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY74050.1 - 1.7e-22 79.6 0.1 1.3e-20 73.5 0.0 3.6 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY74050.1 - 1.2e-15 57.0 0.4 2.2e-14 53.0 0.1 2.6 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 ORY74050.1 - 0.00037 20.6 0.0 0.0013 18.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY74050.1 - 0.0074 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ORY74050.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Abhydrolase_1 PF00561.20 ORY74051.1 - 1.9e-16 60.5 0.0 1.6e-12 47.6 0.0 2.6 1 1 2 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY74051.1 - 1.5e-14 53.8 0.1 1.9e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY74051.1 - 8.6e-14 52.7 0.0 1.2e-13 52.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ORY74051.1 - 1.8e-05 23.6 0.0 2.3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 ORY74051.1 - 5.9e-05 22.8 0.2 0.00012 21.9 0.1 1.5 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 ORY74051.1 - 0.0078 16.3 0.0 0.014 15.5 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Paf1 PF03985.13 ORY74052.1 - 1.1e-57 196.0 0.0 1.3e-57 195.8 0.0 1.0 1 0 0 1 1 1 1 Paf1 IBR PF01485.21 ORY74053.1 - 0.0005 20.2 3.8 0.0005 20.2 3.8 3.1 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain EccE PF11203.8 ORY74053.1 - 0.013 15.8 0.3 0.049 14.0 0.3 2.1 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE DUF2524 PF10732.9 ORY74053.1 - 0.41 11.0 2.7 0.28 11.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) CENP-T_C PF15511.6 ORY74054.1 - 2.5e-07 30.8 0.1 3e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY74054.1 - 8.2e-05 22.7 0.1 0.00012 22.2 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY74054.1 - 0.0002 21.7 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY74054.1 - 0.0013 19.1 0.1 0.0015 18.9 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY74054.1 - 0.0014 18.8 0.1 0.0029 17.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY74054.1 - 0.099 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 ORY74055.1 - 1.7e-51 174.0 3.5 1.9e-51 173.8 3.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY74055.1 - 5.1e-05 23.6 0.1 7.7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY74055.1 - 8e-05 22.7 0.1 0.00016 21.8 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 ORY74055.1 - 0.00027 21.6 1.1 0.00032 21.3 1.1 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY74055.1 - 0.00062 20.0 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY74055.1 - 0.016 15.3 0.3 0.024 14.7 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY74055.1 - 0.059 13.4 0.1 0.098 12.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Flavin_Reduct PF01613.18 ORY74057.1 - 9.9e-29 100.4 0.2 1.3e-28 99.9 0.2 1.2 1 0 0 1 1 1 1 Flavin reductase like domain RRM_1 PF00076.22 ORY74058.1 - 8.4e-21 73.6 0.0 1.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 ORY74059.1 - 8e-09 35.2 0.0 1.5e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain SMC_N PF02463.19 ORY74060.1 - 1e-21 77.4 0.0 7.9e-16 58.2 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain DUF4201 PF13870.6 ORY74060.1 - 8.1e-05 22.4 5.3 8.1e-05 22.4 5.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 ORY74060.1 - 8.3e-05 21.6 8.8 8.3e-05 21.6 8.8 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein Fez1 PF06818.15 ORY74060.1 - 0.00036 21.1 4.6 0.00036 21.1 4.6 2.2 2 0 0 2 2 2 1 Fez1 DUF3552 PF12072.8 ORY74060.1 - 0.0019 17.7 9.8 0.0019 17.7 9.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3552) ATG16 PF08614.11 ORY74060.1 - 0.0027 18.0 4.3 0.0027 18.0 4.3 3.2 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) AAA_21 PF13304.6 ORY74060.1 - 0.0027 17.6 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Filament PF00038.21 ORY74060.1 - 0.0031 17.1 17.6 0.035 13.7 1.1 3.2 2 1 1 3 3 3 2 Intermediate filament protein DUF724 PF05266.14 ORY74060.1 - 0.0036 17.2 8.6 0.0036 17.2 8.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF724) ABC_tran PF00005.27 ORY74060.1 - 0.0069 16.9 0.0 0.033 14.7 0.0 2.3 1 1 0 1 1 1 1 ABC transporter BAR_3 PF16746.5 ORY74060.1 - 0.0073 16.0 7.6 0.0073 16.0 7.6 1.9 2 0 0 2 2 2 1 BAR domain of APPL family Sec34 PF04136.15 ORY74060.1 - 0.013 15.4 11.4 0.21 11.5 1.0 3.5 2 1 0 3 3 3 0 Sec34-like family AAA_13 PF13166.6 ORY74060.1 - 0.04 12.6 18.5 0.12 11.0 18.6 1.7 1 1 0 1 1 1 0 AAA domain DUF16 PF01519.16 ORY74060.1 - 0.042 14.3 17.0 1 9.9 5.3 3.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 MMADHC PF10229.9 ORY74060.1 - 0.062 13.0 0.5 0.1 12.3 0.5 1.3 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein Med28 PF11594.8 ORY74060.1 - 0.073 13.2 4.8 1.1 9.3 0.4 2.4 2 1 0 2 2 2 0 Mediator complex subunit 28 Baculo_PEP_C PF04513.12 ORY74060.1 - 0.076 13.1 3.1 3.3 7.8 0.9 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 ORY74060.1 - 0.076 11.4 17.0 0.11 10.9 17.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Prominin PF05478.11 ORY74060.1 - 0.081 10.9 6.5 0.5 8.3 0.3 2.0 2 0 0 2 2 2 0 Prominin DUF1664 PF07889.12 ORY74060.1 - 0.2 11.7 16.2 0.089 12.8 3.0 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 ORY74060.1 - 0.26 10.5 14.4 0.21 10.8 1.9 2.6 2 1 0 2 2 2 0 TMPIT-like protein HrpB7 PF09486.10 ORY74060.1 - 0.66 10.3 18.7 0.77 10.1 3.5 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Lectin_N PF03954.14 ORY74060.1 - 0.81 9.4 6.7 5 6.9 0.3 2.9 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain LXG PF04740.12 ORY74060.1 - 0.89 9.2 13.7 0.069 12.9 1.5 2.7 2 1 0 2 2 2 0 LXG domain of WXG superfamily PEP-utilisers_N PF05524.13 ORY74060.1 - 0.91 9.7 13.3 7.2 6.8 8.5 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal GAS PF13851.6 ORY74060.1 - 0.92 8.8 26.4 0.12 11.7 7.2 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 ORY74060.1 - 0.96 9.5 27.3 0.059 13.4 5.9 3.5 2 2 1 3 3 3 0 Designed helical repeat protein 10 domain SHE3 PF17078.5 ORY74060.1 - 1 9.0 16.6 0.034 13.9 3.2 2.3 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 IFT57 PF10498.9 ORY74060.1 - 1.2 8.0 17.2 0.029 13.3 2.8 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 FlaC_arch PF05377.11 ORY74060.1 - 1.8 9.0 12.7 28 5.2 0.0 4.4 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 ORY74060.1 - 2.3 8.7 10.8 17 6.0 0.7 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.6 ORY74060.1 - 2.5 8.4 7.2 1.1 9.6 1.8 2.6 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 5_nucleotid PF05761.14 ORY74060.1 - 2.8 6.8 8.8 0.6 9.0 3.9 2.3 1 1 1 2 2 2 0 5' nucleotidase family Fib_alpha PF08702.10 ORY74060.1 - 3.1 8.0 11.6 2.9 8.1 2.7 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tho2 PF11262.8 ORY74060.1 - 3.2 6.9 10.6 1.3 8.2 1.4 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 BLOC1S3 PF15753.5 ORY74060.1 - 3.2 7.9 10.2 2.3 8.3 0.3 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4763 PF15960.5 ORY74060.1 - 3.8 6.8 12.9 0.74 9.1 0.5 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4763) cwf21 PF08312.12 ORY74060.1 - 4.4 7.5 6.2 1e+02 3.2 6.2 2.8 1 1 0 1 1 1 0 cwf21 domain DUF3584 PF12128.8 ORY74060.1 - 4.6 4.6 20.1 8.7 3.7 20.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) BLOC1_2 PF10046.9 ORY74060.1 - 5.2 7.4 19.6 14 6.1 0.9 3.9 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 ORY74060.1 - 5.2 7.1 15.1 1.8 8.6 3.4 3.2 1 1 2 3 3 3 0 Laminin Domain II Exonuc_VII_L PF02601.15 ORY74060.1 - 6.1 6.3 12.9 1.5e+02 1.7 12.9 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit MscS_porin PF12795.7 ORY74060.1 - 6.2 6.3 17.0 2 7.9 7.3 2.8 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Bacillus_HBL PF05791.11 ORY74060.1 - 7.6 6.3 12.7 1 9.2 2.7 2.4 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Med9 PF07544.13 ORY74060.1 - 7.9 6.6 11.6 1.4 9.1 0.7 3.5 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 ORY74060.1 - 8.5 6.9 30.6 1.4 9.5 3.9 3.2 1 1 1 3 3 3 0 Apg6 coiled-coil region Prp19 PF08606.11 ORY74061.1 - 1.1e-28 99.0 1.1 1.9e-28 98.2 1.1 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 ORY74061.1 - 3e-22 78.5 3.8 0.00042 21.0 0.1 6.9 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY74061.1 - 6e-15 55.3 0.0 0.00034 20.9 0.0 5.4 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 ORY74061.1 - 0.0052 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 ORY74061.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Nop PF01798.18 ORY74062.1 - 1.1e-82 277.0 0.3 1.1e-82 277.0 0.3 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORY74062.1 - 1.8e-16 60.2 0.1 1.8e-16 60.2 0.1 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RR_TM4-6 PF06459.12 ORY74062.1 - 4.8 6.9 17.5 9 6.0 17.5 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 ORY74063.1 - 1.8e-07 29.7 0.0 4.5e-05 21.8 0.0 2.4 2 1 0 2 2 2 2 Hsp70 protein BcrAD_BadFG PF01869.20 ORY74063.1 - 0.074 12.5 0.4 2.9 7.3 0.0 2.9 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Polysacc_deac_1 PF01522.21 ORY74064.1 - 6.4e-29 100.4 0.0 1.1e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4667 PF15700.5 ORY74064.1 - 0.00089 19.4 1.8 0.00089 19.4 1.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) CNDH2_M PF16869.5 ORY74064.1 - 2.3 8.9 9.3 38 5.0 7.2 2.2 2 0 0 2 2 2 0 PF16858 Pex14_N PF04695.13 ORY74064.1 - 2.4 8.8 10.8 0.55 10.9 2.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ecl1 PF12855.7 ORY74064.1 - 4.3 8.5 23.5 5.1 8.2 3.0 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins ATG16 PF08614.11 ORY74065.1 - 3.3e-05 24.2 3.2 3.3e-05 24.2 3.2 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Uso1_p115_C PF04871.13 ORY74065.1 - 0.02 15.3 4.8 0.02 15.3 4.8 1.7 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Med9 PF07544.13 ORY74065.1 - 0.1 12.7 4.2 0.65 10.1 4.2 2.2 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3292 PF11696.8 ORY74065.1 - 0.12 10.7 3.5 0.19 10.1 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Spc7 PF08317.11 ORY74065.1 - 0.15 11.0 4.4 0.25 10.2 4.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 ORY74065.1 - 0.25 11.2 6.3 0.16 11.8 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TFIIA PF03153.13 ORY74065.1 - 0.33 10.9 6.4 0.49 10.3 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FmiP_Thoc5 PF09766.9 ORY74065.1 - 0.44 9.8 6.2 0.76 9.0 6.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 SlyX PF04102.12 ORY74065.1 - 1.7 9.4 7.4 2.1 9.0 2.9 3.4 2 1 1 3 3 3 0 SlyX UQ_con PF00179.26 ORY74066.1 - 2.4e-48 163.3 0.0 2.8e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY74066.1 - 0.069 12.8 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B MMS19_C PF12460.8 ORY74067.1 - 1.1e-105 354.2 0.2 1.3e-104 350.7 0.0 2.8 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 ORY74067.1 - 1e-86 290.8 0.0 7e-85 284.7 0.0 3.7 5 0 0 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 ORY74067.1 - 0.00022 21.6 13.8 0.075 13.4 0.0 6.3 5 1 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 ORY74067.1 - 0.0012 19.3 11.7 2.5 8.7 0.1 6.9 7 0 0 7 7 7 2 HEAT-like repeat HEAT PF02985.22 ORY74067.1 - 0.33 11.3 11.0 1.4 9.4 0.1 6.0 6 0 0 6 6 6 0 HEAT repeat DNA_pol_B PF00136.21 ORY74068.1 - 9.9e-110 367.4 0.0 1.3e-109 366.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 ORY74068.1 - 1.4e-62 210.8 0.3 2.6e-62 209.8 0.3 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 ORY74068.1 - 1.2e-24 87.1 0.0 2.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 ORY74068.1 - 8.6e-21 73.8 3.7 2.8e-20 72.1 3.7 2.0 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DUF1744 PF08490.12 ORY74068.1 - 0.035 12.7 0.1 0.055 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) PAP_PilO PF06864.12 ORY74068.1 - 0.81 8.4 3.0 1.3 7.8 1.5 2.1 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Bud13 PF09736.9 ORY74068.1 - 2.4 8.6 14.8 0.018 15.4 5.7 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex CDC45 PF02724.14 ORY74068.1 - 8.7 4.5 7.9 14 3.9 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein FA_hydroxylase PF04116.13 ORY74069.1 - 3.7e-22 79.1 7.7 3.7e-22 79.1 7.7 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily VASt PF16016.5 ORY74070.1 - 5.7e-36 124.2 0.0 1.2e-35 123.2 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ORY74070.1 - 3.7e-23 81.6 0.0 6.3e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Cation_ATPase_C PF00689.21 ORY74071.1 - 9.8e-47 159.0 8.4 9.8e-47 159.0 8.4 2.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY74071.1 - 5.8e-37 127.0 0.1 5.8e-37 127.0 0.1 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY74071.1 - 9.4e-19 67.3 0.0 2.4e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY74071.1 - 1.6e-17 64.5 0.6 5.4e-17 62.8 0.6 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY74071.1 - 6.7e-13 48.1 0.0 1.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY74071.1 - 0.00025 20.9 1.1 0.0081 15.9 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Bromodomain PF00439.25 ORY74072.1 - 4.7e-10 39.4 0.0 9.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain TFIIF_alpha PF05793.12 ORY74072.1 - 0.12 11.0 29.4 0.17 10.5 29.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vps39_2 PF10367.9 ORY74073.1 - 2.1e-08 34.6 0.0 4.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 ORY74073.1 - 2.9e-08 33.9 0.9 4.2e-07 30.2 0.0 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 ORY74073.1 - 9.6e-08 32.0 0.0 2.3e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 ORY74073.1 - 0.0026 17.6 0.0 0.023 14.5 0.0 2.5 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_16 PF13432.6 ORY74073.1 - 0.089 13.5 3.1 0.27 11.9 3.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY74073.1 - 0.099 13.3 0.3 1.7 9.5 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat NUDIX PF00293.28 ORY74074.1 - 1.5e-10 41.2 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Aminotran_1_2 PF00155.21 ORY74075.1 - 1.4e-35 123.2 0.0 1.7e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RIIa PF02197.17 ORY74075.1 - 0.015 15.0 0.0 0.59 9.8 0.0 2.7 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit ABC2_membrane PF01061.24 ORY74076.1 - 5.3e-78 261.2 53.6 8.7e-45 152.7 21.5 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY74076.1 - 4.6e-40 137.3 0.0 9.1e-20 71.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY74076.1 - 6e-24 83.8 11.2 1.1e-23 83.0 0.1 3.5 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORY74076.1 - 3.6e-11 42.8 38.0 3e-08 33.1 21.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 ORY74076.1 - 7.8e-05 22.3 1.5 0.016 14.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY74076.1 - 0.00012 22.0 0.2 0.22 11.3 0.0 3.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY74076.1 - 0.00039 20.9 3.7 0.0032 17.9 0.1 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 ORY74076.1 - 0.00051 19.7 0.1 0.017 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY74076.1 - 0.00056 19.9 0.7 0.0023 17.8 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 ORY74076.1 - 0.0024 17.8 0.2 0.53 10.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 ORY74076.1 - 0.006 16.3 3.1 1.3 8.7 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 ORY74076.1 - 0.0074 16.8 0.0 0.07 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY74076.1 - 0.011 16.0 1.9 0.59 10.4 0.0 3.0 3 1 1 4 4 2 0 AAA domain cobW PF02492.19 ORY74076.1 - 0.046 13.3 1.5 0.54 9.8 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 ORY74076.1 - 0.063 13.4 0.1 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY74076.1 - 0.072 13.3 1.3 1.3 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY74076.1 - 0.099 13.1 1.6 0.47 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY74076.1 - 0.11 12.9 0.1 6 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain EcoEI_R_C PF08463.10 ORY74076.1 - 0.13 12.4 0.4 0.22 11.6 0.4 1.3 1 0 0 1 1 1 0 EcoEI R protein C-terminal ABC_trans_N PF14510.6 ORY74076.1 - 0.13 12.9 0.1 0.44 11.2 0.1 2.0 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_28 PF13521.6 ORY74076.1 - 0.28 11.4 2.3 0.23 11.7 0.1 2.0 2 0 0 2 2 1 0 AAA domain Kinesin PF00225.23 ORY74077.1 - 5.7e-80 268.7 0.0 1.6e-79 267.3 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY74077.1 - 4.4e-09 36.4 0.0 2.8e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding DUF87 PF01935.17 ORY74077.1 - 1 9.4 5.7 7.9 6.5 0.9 3.3 2 1 0 2 2 2 0 Helicase HerA, central domain BTB PF00651.31 ORY74078.1 - 8.6e-05 22.7 0.1 0.038 14.2 0.0 2.9 3 0 0 3 3 3 2 BTB/POZ domain Plasmodium_Vir PF05795.11 ORY74078.1 - 0.16 11.3 0.5 0.23 10.8 0.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Scm3 PF10384.9 ORY74079.1 - 1.5e-05 24.6 0.8 1.5e-05 24.6 0.8 3.7 4 0 0 4 4 4 2 Centromere protein Scm3 TetR_C_28 PF17937.1 ORY74079.1 - 0.58 10.6 3.2 1.4 9.4 0.3 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Cwf_Cwc_15 PF04889.12 ORY74079.1 - 0.99 9.1 6.1 14 5.4 0.1 3.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein PX PF00787.24 ORY74081.1 - 2.1e-20 72.8 0.0 6.4e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY74081.1 - 0.00094 18.8 6.4 0.0067 16.0 1.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 ORY74081.1 - 0.004 16.8 0.8 0.006 16.3 0.1 1.6 2 0 0 2 2 2 1 BAR domain Destabilase PF05497.12 ORY74081.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Destabilase FAM92 PF06730.11 ORY74081.1 - 0.18 11.2 3.5 0.34 10.3 0.6 2.1 2 0 0 2 2 2 0 FAM92 protein 1-cysPrx_C PF10417.9 ORY74082.1 - 0.0022 17.8 0.2 17 5.3 0.0 4.3 4 0 0 4 4 4 1 C-terminal domain of 1-Cys peroxiredoxin Gly_rich PF12810.7 ORY74082.1 - 0.0056 16.6 10.0 0.0069 16.3 9.3 1.5 1 1 0 1 1 1 1 Glycine rich protein DUF3649 PF12365.8 ORY74084.1 - 3.3 7.5 8.4 0.08 12.7 2.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) SGTA_dimer PF16546.5 ORY74085.1 - 4e-21 74.6 0.2 4e-21 74.6 0.2 1.7 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_11 PF13414.6 ORY74085.1 - 4.3e-05 23.1 0.4 6.5e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.28 ORY74085.1 - 0.00087 19.0 0.4 0.0015 18.2 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY74085.1 - 0.0015 18.5 0.2 0.0027 17.7 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY74085.1 - 0.007 17.1 0.1 0.018 15.8 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat CDC45 PF02724.14 ORY74086.1 - 2.1e-193 644.2 0.0 2.6e-193 643.8 0.0 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 ORY74086.1 - 1.6 8.8 11.9 0.045 13.9 3.2 2.1 2 0 0 2 2 2 0 YL1 nuclear protein NPAT_C PF15712.5 ORY74086.1 - 2 7.0 2.9 2.8 6.5 2.9 1.1 1 0 0 1 1 1 0 NPAT C terminus PDCD2_C PF04194.13 ORY74087.1 - 2.8e-30 105.7 0.0 1.8e-29 103.0 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PTPA PF03095.15 ORY74088.1 - 1.3e-101 340.1 0.0 1.5e-101 339.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein 1-cysPrx_C PF10417.9 ORY74089.1 - 0.0022 17.8 0.2 17 5.3 0.0 4.3 4 0 0 4 4 4 1 C-terminal domain of 1-Cys peroxiredoxin Gly_rich PF12810.7 ORY74089.1 - 0.0056 16.6 10.0 0.0069 16.3 9.3 1.5 1 1 0 1 1 1 1 Glycine rich protein F-box-like PF12937.7 ORY74090.1 - 0.026 14.4 2.3 0.081 12.8 2.3 2.0 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 ORY74093.1 - 2.5e-51 174.6 0.0 4.5e-51 173.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY74093.1 - 1.1e-37 129.7 0.0 3.2e-37 128.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY74093.1 - 4.5e-06 25.7 0.1 9.5e-06 24.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY74093.1 - 0.0032 17.4 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY74093.1 - 0.02 14.2 0.0 0.098 12.0 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 ORY74093.1 - 0.094 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 ORY74094.1 - 0.00038 20.3 0.8 0.00093 19.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY74094.1 - 0.088 13.3 0.5 7.6 7.1 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) zf-HIT PF04438.16 ORY74095.1 - 6.4e-06 25.9 5.9 1.2e-05 25.1 5.9 1.3 1 0 0 1 1 1 1 HIT zinc finger VATC PF18716.1 ORY74095.1 - 2.9 7.8 7.2 7.5 6.5 7.2 1.8 1 1 0 1 1 1 0 Vms1-associating treble clef domain zf-MYND PF01753.18 ORY74095.1 - 3.4 7.8 10.6 6.2 7.0 10.6 1.5 1 0 0 1 1 1 0 MYND finger DUF1712 PF08217.11 ORY74096.1 - 5.2e-15 55.0 0.0 7.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Cytochrom_C1 PF02167.15 ORY74097.1 - 5.8e-96 320.4 0.0 7.8e-96 320.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ORY74097.1 - 0.00083 19.6 0.0 0.0017 18.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ORY74097.1 - 0.08 14.1 0.0 0.28 12.3 0.0 2.2 1 1 0 1 1 1 0 Cytochrome c ABC_tran PF00005.27 ORY74098.1 - 5.3e-22 78.8 0.0 1.7e-21 77.1 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY74098.1 - 1.2e-06 28.6 0.2 0.064 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY74098.1 - 0.00012 21.6 0.0 0.017 14.5 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY74098.1 - 0.0047 16.7 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ORY74098.1 - 0.03 14.8 0.6 0.073 13.6 0.1 1.7 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY74098.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 ORY74098.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORY74098.1 - 0.16 11.7 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Spc7 PF08317.11 ORY74099.1 - 7.4e-50 169.6 0.1 1.2e-49 168.9 0.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 ORY74099.1 - 0.0032 15.8 0.9 0.0032 15.8 0.9 4.7 1 1 2 4 4 4 2 N-terminus of kinetochore NMS complex subunit Spc7 EzrA PF06160.12 ORY74099.1 - 0.012 13.8 1.9 0.087 11.0 0.8 2.3 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA SHE3 PF17078.5 ORY74099.1 - 0.11 12.2 2.7 0.15 11.7 1.2 1.9 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 CENP-N PF05238.13 ORY74101.1 - 6.1e-37 127.9 0.0 7.7e-28 97.9 0.1 2.0 2 0 0 2 2 2 2 Kinetochore protein CHL4 like HSP20 PF00011.21 ORY74261.1 - 0.00014 21.9 0.1 0.00019 21.5 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BCNT PF07572.12 ORY74261.1 - 0.047 13.8 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Bucentaur or craniofacial development ArsA_HSP20 PF17886.1 ORY74261.1 - 0.064 12.8 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Sugar_tr PF00083.24 ORY74262.1 - 1.5e-101 340.5 24.8 1.7e-101 340.3 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY74262.1 - 1.5e-31 109.6 40.2 6.9e-29 100.9 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY74262.1 - 1e-06 27.5 2.8 1e-06 27.5 2.8 2.8 3 1 1 4 4 4 1 Fungal trichothecene efflux pump (TRI12) PT-VENN PF04829.13 ORY74262.1 - 0.048 13.7 0.3 0.23 11.6 0.3 2.3 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif PaaX PF07848.12 ORY74263.1 - 0.07 13.4 0.0 0.78 10.0 0.0 2.8 4 0 0 4 4 4 0 PaaX-like protein Phage_DsbA PF11126.8 ORY74263.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DsbA TRAM_LAG1_CLN8 PF03798.16 ORY74265.1 - 8.9e-26 90.9 14.0 8.9e-26 90.9 14.0 1.7 2 0 0 2 2 2 1 TLC domain HSP20 PF00011.21 ORY74267.1 - 4e-09 36.5 0.0 4.5e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY74267.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 HSP20-like domain found in ArsA F-box-like PF12937.7 ORY74268.1 - 1.6e-07 31.1 0.3 5e-07 29.5 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY74268.1 - 8.4e-06 25.5 0.3 1.9e-05 24.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain Methyltr_RsmB-F PF01189.17 ORY74269.1 - 8.1e-71 237.8 0.0 1.3e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 ORY74269.1 - 5.7e-07 30.0 0.0 1.7e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 ORY74269.1 - 0.0093 16.1 0.0 0.024 14.8 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Glutenin_hmw PF03157.13 ORY74269.1 - 1.1 7.6 13.7 1.4 7.2 13.7 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit PBP_N PF17093.5 ORY74269.1 - 7.1 6.9 6.6 0.69 10.2 1.2 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus MFS_1 PF07690.16 ORY74270.1 - 1e-22 80.6 37.9 1e-17 64.1 10.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 ORY74271.1 - 6.4e-07 29.2 0.4 1.8e-06 27.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY74271.1 - 4.7e-06 26.3 0.3 1.1e-05 25.1 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY74271.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 F-box BUD22 PF09073.10 ORY74272.1 - 0.59 9.4 11.7 0.91 8.8 11.7 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 ORY74272.1 - 1.1 9.0 9.6 1.2 8.8 0.7 2.5 2 0 0 2 2 2 0 FAM176 family Nop14 PF04147.12 ORY74272.1 - 2.1 6.5 11.5 3.1 5.9 11.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.6 ORY74272.1 - 2.5 8.4 11.2 4.3 7.6 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) cobW PF02492.19 ORY74273.1 - 5.5e-49 166.1 3.9 8.7e-46 155.7 3.9 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORY74273.1 - 2.1e-17 62.8 0.0 1.8e-13 50.2 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 ORY74273.1 - 0.0001 21.4 1.6 0.082 11.9 0.0 3.2 3 1 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Voldacs PF03517.13 ORY74273.1 - 0.033 14.3 2.1 0.089 12.9 2.1 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Histidinol_dh PF00815.20 ORY74274.1 - 4.4e-158 526.6 1.2 6.4e-158 526.0 1.2 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 ORY74274.1 - 9.6e-24 83.0 0.0 2.1e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 ORY74274.1 - 2.1e-14 53.7 0.1 6.7e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 ORY74274.1 - 0.0031 17.7 0.1 0.006 16.7 0.1 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain PhyH PF05721.13 ORY74275.1 - 7.4e-14 52.5 0.0 1.1e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 ORY74276.1 - 2.6e-41 141.7 39.9 2.6e-41 141.7 39.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SKN1 PF03935.15 ORY74277.1 - 1.2e-184 614.4 2.0 1.4e-184 614.2 2.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Thioredoxin_15 PF18403.1 ORY74278.1 - 1.3e-31 110.2 0.0 2.4e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 ORY74278.1 - 4.4e-17 62.3 0.0 2.3e-16 60.0 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 ORY74278.1 - 1.8e-12 47.5 0.0 4e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_14 PF18402.1 ORY74278.1 - 0.014 15.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like domain MFS_1 PF07690.16 ORY74280.1 - 6.8e-29 100.9 31.6 6.8e-29 100.9 31.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY74280.1 - 0.55 8.6 7.2 1 7.7 7.2 1.3 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Tht1 PF04163.12 ORY74281.1 - 6.5e-06 25.2 0.1 9.6e-06 24.6 0.1 1.2 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein PITH PF06201.13 ORY74282.1 - 4e-38 131.0 0.1 5.7e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 ORY74282.1 - 2.5e-25 88.4 0.0 4.3e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY74282.1 - 1.7e-05 25.3 0.0 8.5e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY74282.1 - 6.9e-05 23.1 0.0 0.00064 20.0 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 ORY74282.1 - 0.0004 19.8 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ORY74282.1 - 0.00067 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 ORY74282.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 ORY74282.1 - 0.014 15.3 0.1 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family Sad1_UNC PF07738.13 ORY74282.1 - 0.027 14.5 0.1 0.12 12.4 0.0 2.1 2 1 0 2 2 2 0 Sad1 / UNC-like C-terminal TraF PF13728.6 ORY74282.1 - 0.054 13.3 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein SMC_Nse1 PF07574.13 ORY74283.1 - 1.7e-20 73.8 0.8 6.4e-16 58.8 0.1 2.3 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 ORY74283.1 - 1.8e-07 31.4 2.3 4.4e-07 30.1 2.3 1.7 1 0 0 1 1 1 1 RING-like domain Myc_N PF01056.18 ORY74283.1 - 0.0006 19.8 6.9 0.0011 19.0 6.9 1.4 1 0 0 1 1 1 1 Myc amino-terminal region zf-HC5HC2H PF13771.6 ORY74283.1 - 0.087 13.1 0.6 0.18 12.1 0.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain NPR3 PF03666.13 ORY74283.1 - 0.69 8.6 6.1 1.1 8.0 6.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SWIRM-assoc_2 PF16496.5 ORY74283.1 - 2 7.2 10.1 3 6.6 10.1 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pox_Ag35 PF03286.14 ORY74283.1 - 3.1 7.5 18.5 0.86 9.4 15.1 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRN3 PF05327.11 ORY74283.1 - 4.6 5.7 7.1 8.7 4.7 7.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4746 PF15928.5 ORY74283.1 - 5.8 6.2 8.0 9.7 5.5 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Myosin_head PF00063.21 ORY74284.1 - 9.2e-263 873.5 0.8 2.1e-262 872.3 0.0 2.0 2 1 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.19 ORY74284.1 - 1.3e-25 89.7 1.8 1.3e-25 89.7 1.8 2.9 2 1 1 3 3 3 1 DIL domain IQ PF00612.27 ORY74284.1 - 7.4e-19 65.7 24.1 0.00064 19.3 0.4 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.6 ORY74284.1 - 0.0029 17.9 1.1 0.034 14.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain GAS PF13851.6 ORY74284.1 - 0.034 13.5 21.3 0.091 12.1 21.3 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Myosin_N PF02736.19 ORY74284.1 - 0.054 13.3 0.1 0.3 10.9 0.1 2.2 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Atg14 PF10186.9 ORY74284.1 - 0.09 11.8 15.7 0.24 10.5 15.7 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 ORY74284.1 - 0.22 11.8 13.1 0.089 13.1 4.8 3.1 2 0 0 2 2 2 0 Tup N-terminal DUF4472 PF14739.6 ORY74284.1 - 0.32 11.8 15.1 0.49 11.1 1.3 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) HalX PF08663.10 ORY74284.1 - 0.34 11.3 12.8 1.2 9.5 3.3 3.8 2 1 1 3 3 3 0 HalX domain Spc7 PF08317.11 ORY74284.1 - 0.38 9.6 22.8 1.8 7.4 22.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein AAA_16 PF13191.6 ORY74284.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.1 3 0 0 3 3 2 0 AAA ATPase domain HIP1_clath_bdg PF16515.5 ORY74284.1 - 0.59 10.8 20.2 0.065 13.9 8.3 3.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Nsp1_C PF05064.13 ORY74284.1 - 0.8 9.5 11.3 6.1 6.7 3.6 2.6 2 0 0 2 2 2 0 Nsp1-like C-terminal region Fib_alpha PF08702.10 ORY74284.1 - 1.2 9.3 10.3 0.58 10.3 4.9 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 ORY74284.1 - 2.1 8.4 20.9 7.2 6.7 12.6 2.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 ORY74284.1 - 2.4 8.2 22.4 2.3 8.3 2.4 2.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 ORY74284.1 - 3.1 6.3 12.1 4.1 5.9 11.0 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 ORY74284.1 - 3.6 8.1 13.2 3.1 8.3 0.2 4.2 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 ORY74284.1 - 4.4 8.0 14.5 1.8 9.3 1.9 3.4 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Metal_resist PF13801.6 ORY74284.1 - 4.4 7.5 15.3 0.049 13.8 4.4 3.2 3 0 0 3 3 3 0 Heavy-metal resistance Mod_r PF07200.13 ORY74284.1 - 4.6 7.3 22.0 7.2 6.7 3.0 3.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BRE1 PF08647.11 ORY74284.1 - 8 6.6 23.8 4.9 7.3 1.9 3.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Lyase_1 PF00206.20 ORY74285.1 - 1.5e-86 290.6 0.0 2.1e-86 290.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 ORY74285.1 - 6.9e-24 84.4 0.0 2e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF202 PF02656.15 ORY74286.1 - 9.8e-09 35.5 4.4 5.9e-08 33.0 4.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF202) Yip1 PF04893.17 ORY74286.1 - 0.033 13.9 2.6 0.043 13.5 2.6 1.1 1 0 0 1 1 1 0 Yip1 domain Asparaginase PF00710.20 ORY74287.1 - 3.5e-59 199.6 0.0 7.5e-59 198.5 0.0 1.6 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 ORY74287.1 - 2.6e-28 98.5 0.0 4.9e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 ORY74287.1 - 5.7e-07 30.0 0.0 1.4e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY74287.1 - 3e-05 24.3 1.8 8.3e-05 22.9 0.4 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 ORY74287.1 - 6.8e-05 23.4 0.6 0.00016 22.1 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY74287.1 - 0.00021 21.5 0.0 0.00054 20.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY74287.1 - 0.00054 20.2 0.2 0.038 14.5 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat MFS_1 PF07690.16 ORY74289.1 - 7.6e-23 81.0 39.3 1.9e-19 69.8 16.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM100 PF16311.5 ORY74289.1 - 0.016 14.8 0.6 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 Transmembrane protein 100 Vpu PF00558.19 ORY74289.1 - 0.16 11.7 1.3 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Vpu protein LapA_dom PF06305.11 ORY74289.1 - 6.6 6.6 6.6 2.4 8.1 1.6 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Asp PF00026.23 ORY74290.1 - 6.7e-62 209.7 4.5 9e-62 209.3 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY74290.1 - 4.4e-06 27.0 6.9 0.00033 20.9 6.9 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY74290.1 - 0.0015 18.3 0.0 0.0064 16.3 0.0 1.9 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY74290.1 - 0.073 13.7 6.4 5.7 7.6 3.9 3.0 2 1 0 2 2 2 0 Aspartyl protease ORC5_C PF14630.6 ORY74291.1 - 1.5e-38 132.9 0.0 2.9e-38 132.0 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PBP1_TM PF14812.6 ORY74291.1 - 4.2 7.8 9.9 0.69 10.3 3.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 ORY74293.1 - 1e-14 54.3 27.9 1e-14 54.3 27.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily La PF05383.17 ORY74294.1 - 4.3e-14 52.3 0.0 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 2 La domain WD40 PF00400.32 ORY74295.1 - 1.9e-09 38.0 1.3 0.28 12.1 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Lactonase PF10282.9 ORY74295.1 - 0.0043 16.4 0.0 0.053 12.8 0.0 1.8 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Peptidase_M1 PF01433.20 ORY74296.1 - 6.7e-68 228.5 0.3 9.8e-68 228.0 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORY74296.1 - 7.3e-62 209.7 0.0 1e-61 209.2 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ORY74296.1 - 2.9e-21 76.5 0.0 8.4e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M30 PF10460.9 ORY74296.1 - 0.038 12.9 0.3 0.083 11.8 0.3 1.5 1 0 0 1 1 1 0 Peptidase M30 Tht1 PF04163.12 ORY74297.1 - 6.8e-06 25.1 0.2 8.4e-06 24.8 0.2 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein EF_TS PF00889.19 ORY74300.1 - 1e-14 54.7 0.0 3.3e-14 53.0 0.0 1.8 1 1 1 2 2 2 1 Elongation factor TS Gar1 PF04410.14 ORY74301.1 - 7.1e-41 139.5 0.0 7.1e-41 139.5 0.0 1.9 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region AF-4 PF05110.13 ORY74301.1 - 0.0014 16.8 10.9 0.0017 16.5 10.9 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Apt1 PF10351.9 ORY74301.1 - 0.023 13.6 2.5 0.025 13.5 2.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain IMUP PF15761.5 ORY74301.1 - 0.098 13.4 21.2 0.85 10.3 19.9 2.3 1 1 1 2 2 2 0 Immortalisation up-regulated protein Macoilin PF09726.9 ORY74301.1 - 0.24 9.9 2.7 0.29 9.7 2.7 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 ORY74301.1 - 0.8 7.9 10.8 1.2 7.4 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF755 PF05501.11 ORY74301.1 - 1.9 8.8 8.4 0.12 12.7 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) BUD22 PF09073.10 ORY74301.1 - 2.5 7.4 24.6 0.029 13.7 17.4 1.4 2 0 0 2 2 2 0 BUD22 Mitofilin PF09731.9 ORY74303.1 - 2.6e-108 363.6 22.9 4.1e-108 362.9 22.9 1.3 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.18 ORY74303.1 - 0.0022 17.9 30.7 0.0037 17.1 6.9 2.8 2 1 0 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 ORY74303.1 - 0.019 15.5 10.4 0.019 15.5 10.4 3.2 2 1 0 2 2 2 0 YtxH-like protein TMP_2 PF06791.13 ORY74303.1 - 1.2 8.8 17.6 0.044 13.5 10.5 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein DUF4083 PF13314.6 ORY74304.1 - 0.026 14.4 0.6 0.041 13.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF2749 PF10907.8 ORY74304.1 - 0.26 11.5 1.5 0.53 10.5 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) S10_plectin PF03501.15 ORY74305.1 - 8.9e-43 144.3 0.1 1.1e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Stig1 PF04885.13 ORY74306.1 - 5.9e-09 36.5 211.8 0.16 12.4 15.7 14.4 3 1 10 14 14 14 12 Stigma-specific protein, Stig1 ubiquitin PF00240.23 ORY74307.1 - 4.5e-18 64.8 0.0 6.7e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 ORY74307.1 - 1.1e-07 31.6 3.6 2.2e-07 30.6 0.0 2.6 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 ORY74307.1 - 5.4e-06 26.1 0.0 9.7e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY74307.1 - 5.5e-05 23.7 0.0 9.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain RPN13_C PF16550.5 ORY74307.1 - 0.029 14.5 0.1 0.029 14.5 0.1 2.1 2 0 0 2 2 2 0 UCH-binding domain Ubiquitin_4 PF18036.1 ORY74307.1 - 0.03 14.3 0.0 0.24 11.5 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain CUE PF02845.16 ORY74307.1 - 0.082 12.6 1.2 11 5.9 1.1 2.5 2 0 0 2 2 2 0 CUE domain GerD PF17898.1 ORY74307.1 - 0.83 9.6 8.0 0.48 10.4 1.0 2.9 2 1 0 2 2 2 0 Spore germination GerD central core domain STI1 PF17830.1 ORY74307.1 - 0.96 9.4 21.0 0.82 9.6 1.6 3.8 2 1 1 3 3 3 0 STI1 domain 2OG-FeII_Oxy_2 PF13532.6 ORY74308.1 - 7.5e-25 88.3 0.0 1.3e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sdh_cyt PF01127.22 ORY74309.1 - 1.7e-18 66.8 0.4 2e-18 66.5 0.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PX PF00787.24 ORY74310.1 - 4e-07 30.0 0.0 1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 PX domain Anillin_N PF16018.5 ORY74310.1 - 0.81 10.3 0.0 0.81 10.3 0.0 3.2 3 0 0 3 3 3 0 Anillin N-terminus Bot1p PF12298.8 ORY74312.1 - 8.2e-21 74.9 0.2 6e-20 72.1 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein F-box PF00646.33 ORY74313.1 - 0.00073 19.4 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain RA PF00788.23 ORY74314.1 - 2.1e-13 50.7 0.0 5.5e-12 46.2 0.0 3.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 ORY74314.1 - 1.2e-06 28.0 0.5 5.9e-06 25.8 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORY74314.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Ribosomal_L27 PF01016.19 ORY74316.1 - 9.4e-36 121.7 2.3 1.3e-35 121.3 2.3 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein PRP38 PF03371.15 ORY74317.1 - 4.4e-61 205.8 1.3 5.3e-61 205.5 1.3 1.1 1 0 0 1 1 1 1 PRP38 family Proteasome PF00227.26 ORY74318.1 - 8.7e-50 168.9 0.1 1.3e-49 168.3 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Fungal_trans PF04082.18 ORY74320.1 - 1.3e-21 76.8 0.0 2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY74320.1 - 2.1e-08 34.2 6.9 3.5e-08 33.4 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.14 ORY74321.1 - 1.5e-38 132.2 8.8 1.7e-38 132.0 8.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DEAD PF00270.29 ORY74322.1 - 6.2e-46 156.4 0.0 1.6e-45 155.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY74322.1 - 1.3e-27 96.3 0.0 4.9e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY74322.1 - 0.00028 20.9 0.0 0.0007 19.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GCFC PF07842.12 ORY74323.1 - 9.2e-82 274.8 0.7 1.3e-81 274.3 0.7 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 ORY74323.1 - 3.3e-13 49.3 6.8 1.8e-12 46.9 6.8 2.4 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 ORY74323.1 - 3.6e-06 27.3 20.7 3.6e-06 27.3 20.7 3.0 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 ORY74323.1 - 0.88 9.7 11.0 0.049 13.7 2.4 3.4 3 0 0 3 3 3 0 G-patch domain SRP14 PF02290.15 ORY74324.1 - 9.6e-25 86.8 0.0 2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein MFS_1 PF07690.16 ORY74325.1 - 1.2e-31 109.9 36.1 1.2e-31 109.9 36.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 ORY74325.1 - 5.6 5.1 8.2 42 2.2 8.2 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family NDUF_B12 PF08122.12 ORY74325.1 - 5.9 7.0 0.0 5.9 7.0 0.0 3.8 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase B12 subunit family HSP20 PF00011.21 ORY74326.1 - 2.8e-15 56.3 0.1 3.3e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY74326.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Abhydrolase_3 PF07859.13 ORY74327.1 - 7.3e-44 150.1 0.0 1.2e-43 149.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY74327.1 - 5.2e-15 55.2 0.0 3.1e-13 49.3 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Caldesmon PF02029.15 ORY74327.1 - 0.11 11.2 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Caldesmon UCH PF00443.29 ORY74328.1 - 2.8e-51 174.5 0.0 6.2e-51 173.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY74328.1 - 1.4e-25 90.5 0.3 6.8e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase GST_N_3 PF13417.6 ORY74329.1 - 1.3e-09 38.3 0.0 2.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY74329.1 - 5e-07 29.9 0.0 9.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY74329.1 - 9.7e-06 25.5 0.2 2.6e-05 24.2 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY74329.1 - 2e-05 24.8 0.1 4.1e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ORY74329.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HSP70 PF00012.20 ORY74330.1 - 2.1e-258 858.5 5.2 2.4e-258 858.3 5.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY74330.1 - 1.5e-16 60.1 1.4 1e-15 57.4 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 ORY74330.1 - 0.0089 15.0 0.2 0.11 11.5 0.3 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 ORY74330.1 - 0.073 12.3 1.6 0.18 11.0 0.2 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Dicty_REP PF05086.12 ORY74331.1 - 2.6 5.9 3.1 2.7 5.9 3.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Amelin PF05111.12 ORY74331.1 - 3.2 6.8 7.8 4.2 6.4 7.8 1.2 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) SSP160 PF06933.11 ORY74331.1 - 6.7 4.8 12.2 6.7 4.8 12.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dimer_Tnp_hAT PF05699.14 ORY74332.1 - 0.06 13.1 1.4 0.49 10.2 0.2 2.5 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region DUF659 PF04937.15 ORY74332.1 - 0.15 11.9 0.0 0.62 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF 659) Peptidase_C97 PF05903.14 ORY74499.1 - 6.4e-35 120.2 0.0 9.6e-35 119.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 ORY74499.1 - 2.2e-15 56.5 0.0 3.9e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY74499.1 - 3.9e-06 27.3 0.1 2e-05 25.0 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY74499.1 - 0.00032 20.2 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORY74499.1 - 0.00095 19.5 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 ORY74499.1 - 0.033 14.4 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin PUL PF08324.11 ORY74499.1 - 0.037 13.3 0.6 0.067 12.4 0.6 1.5 1 0 0 1 1 1 0 PUL domain Thioredoxin_7 PF13899.6 ORY74499.1 - 0.038 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 ORY74499.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Redoxin Mito_carr PF00153.27 ORY74500.1 - 5.7e-21 74.3 10.0 8.4e-08 32.0 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF2378 PF09536.10 ORY74500.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) DUF3712 PF12505.8 ORY74501.1 - 2.4e-129 425.3 67.0 1.1e-23 83.8 0.2 12.8 15 0 0 15 15 15 8 Protein of unknown function (DUF3712) LEA_2 PF03168.13 ORY74501.1 - 2.6e-09 37.5 14.4 0.019 15.5 0.0 9.7 8 0 0 8 8 8 2 Late embryogenesis abundant protein ATPgrasp_N PF18130.1 ORY74501.1 - 0.026 15.1 0.0 8.4 7.0 0.0 3.8 3 0 0 3 3 3 0 ATP-grasp N-terminal domain Pterin_bind PF00809.22 ORY74503.1 - 1.4e-76 257.4 0.0 2.2e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 ORY74503.1 - 1.6e-33 115.5 0.0 4.2e-33 114.2 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 ORY74503.1 - 4.5e-28 98.0 0.0 9.4e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase Ecl1 PF12855.7 ORY74503.1 - 0.083 14.0 1.3 45 5.2 0.0 2.4 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins FTCD_C PF04961.12 ORY74503.1 - 0.13 12.1 0.2 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase CAP PF00188.26 ORY74504.1 - 2.2e-22 80.2 0.1 3e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mito_carr PF00153.27 ORY74505.1 - 6.2e-21 74.1 10.1 8.4e-08 32.0 0.1 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein DUF2378 PF09536.10 ORY74505.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) Sec8_exocyst PF04048.14 ORY74506.1 - 4.4e-17 62.3 0.0 1.3e-16 60.8 0.0 1.9 1 1 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 ORY74506.1 - 0.033 13.5 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DEAD PF00270.29 ORY74507.1 - 1.6e-34 119.2 0.0 8.5e-25 87.5 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY74507.1 - 3.2e-19 69.3 0.0 5.3e-18 65.4 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY74507.1 - 2e-17 63.1 0.0 3.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY74507.1 - 0.042 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Rhodanese PF00581.20 ORY74508.1 - 3.2e-06 27.6 0.0 5.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2_4 PF13894.6 ORY74509.1 - 0.023 15.5 1.4 0.055 14.3 1.4 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1751 PF08551.10 ORY74510.1 - 8.4e-29 100.1 5.4 1.7e-28 99.0 5.4 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 ORY74510.1 - 7.8e-07 29.2 9.2 1.7e-06 28.1 9.2 1.6 1 0 0 1 1 1 1 Rhomboid family Zeta_toxin PF06414.12 ORY74511.1 - 2.5e-25 89.0 0.0 3.5e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 ORY74511.1 - 7.9e-07 29.3 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORY74511.1 - 0.0051 17.2 1.3 0.034 14.6 0.2 2.6 2 1 0 2 2 2 1 AAA domain DUF829 PF05705.14 ORY74512.1 - 1.7e-43 149.2 0.0 2.7e-43 148.6 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ipi1_N PF12333.8 ORY74513.1 - 6.6e-14 52.4 0.0 5.9e-13 49.3 0.0 2.7 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Mrr_cat PF04471.12 ORY74513.1 - 0.00047 20.2 0.0 0.47 10.5 0.0 2.5 2 0 0 2 2 2 2 Restriction endonuclease Nup54 PF13874.6 ORY74514.1 - 6.5e-33 113.8 1.4 1.3e-32 112.9 1.4 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 ORY74514.1 - 7.3e-24 84.4 90.5 4.3e-13 49.9 20.2 4.4 2 1 3 5 5 5 4 Nucleoporin FG repeat region STAG PF08514.11 ORY74514.1 - 0.52 10.3 6.6 0.83 9.6 6.6 1.2 1 0 0 1 1 1 0 STAG domain ACBP PF00887.19 ORY74515.1 - 5.7e-19 68.1 0.0 1.1e-18 67.2 0.0 1.4 1 1 0 1 1 1 1 Acyl CoA binding protein DSPn PF14671.6 ORY74516.1 - 1.2e-27 97.1 0.1 4.2e-26 92.1 0.1 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 ORY74516.1 - 2.4e-15 56.5 0.0 4.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY74516.1 - 0.00049 19.7 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY74516.1 - 0.0027 17.8 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 ORY74516.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TPPII_N PF12583.8 ORY74516.1 - 5.1 7.7 10.3 0.5 11.0 5.2 1.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Rab5ip PF07019.12 ORY74517.1 - 2.7e-20 72.7 7.5 3.2e-20 72.5 7.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2304 PF10066.9 ORY74517.1 - 0.21 11.8 0.1 0.21 11.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) NifU_N PF01592.16 ORY74518.1 - 6.3e-54 181.6 0.1 7.9e-54 181.2 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain RVT_1 PF00078.27 ORY74519.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC_membrane PF00664.23 ORY74520.1 - 3.8e-45 154.7 25.8 4.1e-29 102.1 9.3 3.4 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY74520.1 - 2.5e-44 151.1 0.0 5.4e-27 95.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORY74520.1 - 2.3e-09 37.0 0.0 0.0019 17.7 0.2 3.7 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY74520.1 - 0.0023 18.2 0.6 2.2 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ORY74520.1 - 0.0055 16.3 0.1 1.7 8.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY74520.1 - 0.019 14.2 0.1 1.8 7.7 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain ATPase PF06745.13 ORY74520.1 - 0.033 13.5 3.7 2.4 7.5 0.0 2.6 3 0 0 3 3 3 0 KaiC SbcCD_C PF13558.6 ORY74520.1 - 0.067 13.4 0.2 12 6.3 0.1 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.9 ORY74520.1 - 0.075 11.9 0.7 5.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 ORY74520.1 - 0.081 13.3 0.1 0.59 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ORY74520.1 - 0.1 13.1 0.3 48 4.4 0.2 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY74520.1 - 0.1 12.3 4.5 1.8 8.4 0.1 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY74520.1 - 0.12 12.1 1.4 7.6 6.2 0.0 2.9 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ATP-synt_ab PF00006.25 ORY74520.1 - 0.16 11.6 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AF-4 PF05110.13 ORY74520.1 - 0.37 8.8 3.5 0.67 8.0 3.5 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_23 PF13476.6 ORY74520.1 - 0.52 10.8 7.1 3.6 8.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 ORY74520.1 - 0.91 9.1 2.3 1.2 8.6 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Coatomer_E PF04733.14 ORY74522.1 - 3.7e-21 75.8 0.0 5.5e-21 75.2 0.0 1.3 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 ORY74522.1 - 0.00042 20.2 4.7 0.021 14.9 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY74522.1 - 0.0014 19.1 5.4 0.34 11.4 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY74522.1 - 0.0063 17.2 6.7 0.88 10.6 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY74522.1 - 0.0087 15.8 0.6 0.092 12.6 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY74522.1 - 0.015 15.9 5.0 3.9 8.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY74522.1 - 0.03 13.7 0.5 0.63 9.3 0.1 2.3 2 0 0 2 2 2 0 MalT-like TPR region TPR_8 PF13181.6 ORY74522.1 - 0.087 13.1 0.1 88 3.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NUDIX PF00293.28 ORY74523.1 - 1.5e-10 41.2 0.0 2.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 ORY74523.1 - 1.3e-07 31.6 0.1 0.001 19.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4743) NUDE_C PF04880.13 ORY74524.1 - 3.5e-16 60.2 7.4 3.5e-16 60.2 7.4 4.6 2 1 3 5 5 2 1 NUDE protein, C-terminal conserved region Fez1 PF06818.15 ORY74524.1 - 3.2e-08 34.3 2.2 3.2e-08 34.3 2.2 1.6 2 0 0 2 2 2 1 Fez1 DUF2353 PF09789.9 ORY74524.1 - 0.00062 19.2 9.3 0.0012 18.2 9.3 1.4 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Phlebovirus_NSM PF07246.11 ORY74524.1 - 0.0014 18.1 1.9 1.1 8.5 1.1 2.2 2 0 0 2 2 2 2 Phlebovirus nonstructural protein NS-M ATG16 PF08614.11 ORY74524.1 - 0.0016 18.7 15.6 0.0016 18.7 15.6 2.7 3 1 0 3 3 2 1 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 ORY74524.1 - 0.092 12.8 7.5 0.21 11.6 5.7 2.2 2 0 0 2 2 2 0 Laminin Domain II PRKG1_interact PF15898.5 ORY74524.1 - 0.11 13.4 15.5 0.071 14.0 12.4 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF812 PF05667.11 ORY74524.1 - 0.15 10.9 12.0 0.096 11.6 10.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ZapB PF06005.12 ORY74524.1 - 0.16 12.4 20.5 0.052 14.0 8.2 3.1 2 1 1 3 3 3 0 Cell division protein ZapB HOOK PF05622.12 ORY74524.1 - 0.21 9.7 13.1 0.33 9.0 13.1 1.3 1 0 0 1 1 1 0 HOOK protein V_ATPase_I PF01496.19 ORY74524.1 - 0.27 9.1 0.7 0.42 8.5 0.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 ORY74524.1 - 0.31 9.9 13.1 0.63 8.9 13.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 ORY74524.1 - 0.32 11.2 7.7 0.52 10.5 5.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 ORY74524.1 - 0.38 9.3 4.2 0.61 8.6 4.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF724 PF05266.14 ORY74524.1 - 0.53 10.1 11.9 0.21 11.4 4.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF5082 PF16888.5 ORY74524.1 - 0.75 10.1 6.8 2.3 8.5 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) APG6_N PF17675.1 ORY74524.1 - 0.78 10.3 21.4 0.21 12.1 8.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region IFT57 PF10498.9 ORY74524.1 - 0.78 8.7 9.6 0.12 11.3 6.0 1.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 FPP PF05911.11 ORY74524.1 - 1.1 7.3 12.1 1.8 6.6 12.1 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Cauli_AT PF03233.13 ORY74524.1 - 1.3 9.0 7.6 0.59 10.0 3.8 2.2 2 1 1 3 3 3 0 Aphid transmission protein Seryl_tRNA_N PF02403.22 ORY74524.1 - 1.3 9.3 10.2 8.6 6.6 8.7 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0449 PF15136.6 ORY74524.1 - 1.5 9.3 7.7 4.4 7.8 6.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Filament PF00038.21 ORY74524.1 - 2.2 7.8 17.9 0.31 10.6 14.1 1.4 2 0 0 2 2 1 0 Intermediate filament protein TMPIT PF07851.13 ORY74524.1 - 2.2 7.4 5.6 3.9 6.6 5.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 ORY74524.1 - 3.9 7.5 21.5 1.8 8.6 18.1 2.1 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tektin PF03148.14 ORY74524.1 - 4.6 5.9 19.6 0.55 8.9 15.5 1.4 2 0 0 2 2 2 0 Tektin family Lzipper-MIP1 PF14389.6 ORY74524.1 - 4.7 7.6 12.9 1.7e+02 2.5 11.0 3.6 2 1 1 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 ERM PF00769.19 ORY74524.1 - 5.4 6.8 19.6 8.1 6.2 19.6 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.11 ORY74524.1 - 8.8 7.0 13.7 7.3 7.2 4.1 3.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 ORY74524.1 - 9.5 6.3 17.7 5.6 7.0 5.4 2.6 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein NCBP3 PF10309.9 ORY74525.1 - 8.4e-06 25.5 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 ORY74525.1 - 0.071 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain Sugar_tr PF00083.24 ORY74528.1 - 1.2e-67 228.8 29.2 1.4e-67 228.5 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY74528.1 - 1.1e-22 80.5 26.5 1.1e-22 80.5 26.5 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily ATG7_N PF16420.5 ORY74529.1 - 1.2e-85 287.8 0.0 1.6e-85 287.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 ORY74529.1 - 8.7e-44 149.7 0.0 1.3e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 ORY74529.1 - 0.0011 19.0 0.1 0.006 16.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 ORY74529.1 - 0.015 14.7 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 ORY74529.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Clathrin_H_link PF13838.6 ORY74529.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Clathrin-H-link ApbA PF02558.16 ORY74529.1 - 0.14 11.8 0.1 0.54 9.9 0.0 2.0 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Neuraminidase PF18413.1 ORY74530.1 - 0.087 12.5 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Neuraminidase-like domain XRN_N PF03159.18 ORY74532.1 - 1.8e-99 332.0 0.0 2.2e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 ORY74532.1 - 0.00021 21.2 5.9 0.00033 20.6 5.9 1.3 1 0 0 1 1 1 1 Zinc knuckle Rubredoxin PF00301.20 ORY74532.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Rubredoxin zf-CCHC_3 PF13917.6 ORY74532.1 - 0.075 13.0 0.4 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Poxvirus_B22R_N PF13169.6 ORY74532.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus B22R protein N-terminal XRN_M PF17846.1 ORY74533.1 - 0.0098 14.9 0.0 0.012 14.6 0.0 1.0 1 0 0 1 1 1 1 Xrn1 helical domain DUF4596 PF15363.6 ORY74534.1 - 9.2 6.6 8.5 0.8 10.0 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) RRM_1 PF00076.22 ORY74536.1 - 0.062 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Thioredoxin PF00085.20 ORY74538.1 - 4e-44 148.8 0.2 2e-22 79.1 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 ORY74538.1 - 9.1e-07 29.3 0.2 0.056 13.9 0.1 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 ORY74538.1 - 3e-06 27.3 0.0 0.019 14.9 0.0 3.3 3 0 0 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY74538.1 - 8.3e-05 22.1 0.0 0.0059 16.0 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ORY74538.1 - 0.00014 21.9 0.1 0.24 11.6 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 ORY74538.1 - 0.00061 20.1 0.1 3.5 8.0 0.0 3.5 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.6 ORY74538.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Bacteriocin_IIc PF10439.9 ORY74538.1 - 0.033 14.3 0.9 0.12 12.5 0.9 1.9 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Get5_C PF18514.1 ORY74538.1 - 0.037 13.7 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 Get5 C-terminal domain F-box-like PF12937.7 ORY74539.1 - 7.7e-06 25.7 0.7 1.7e-05 24.6 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY74539.1 - 0.023 14.5 0.1 0.068 13.1 0.1 1.8 1 0 0 1 1 1 0 F-box domain Zn_clus PF00172.18 ORY74540.1 - 0.00052 20.1 10.3 0.0012 19.0 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY74540.1 - 0.00094 18.3 1.0 0.0017 17.5 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3961 PF13106.6 ORY74540.1 - 0.015 14.9 0.0 0.044 13.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) 3Beta_HSD PF01073.19 ORY74541.1 - 4.6e-11 42.2 0.0 7.6e-11 41.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY74541.1 - 4.1e-09 36.2 0.0 7.9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY74541.1 - 2.1e-08 33.7 0.0 8.4e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY74541.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY74541.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 ORY74541.1 - 0.059 12.8 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.16 ORY74542.1 - 1.7e-26 93.0 30.9 1.7e-26 93.0 30.9 2.3 1 1 2 3 3 3 1 Major Facilitator Superfamily HTH_23 PF13384.6 ORY74542.1 - 0.16 11.8 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain Longin PF13774.6 ORY74543.1 - 5.7e-25 87.2 0.0 8.1e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 ORY74543.1 - 8.8e-14 51.1 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin HATPase_c PF02518.26 ORY74544.1 - 1.9e-22 79.9 0.1 3.6e-22 79.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY74544.1 - 1.7e-14 53.9 0.0 7.1e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 ORY74544.1 - 2.7e-11 43.3 0.5 7.9e-11 41.8 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 ORY74544.1 - 0.00027 21.2 0.0 1.9 8.8 0.0 4.2 4 0 0 4 4 4 1 GAF domain GAF_3 PF13492.6 ORY74544.1 - 0.0073 16.7 0.0 1.9 8.8 0.0 3.9 5 0 0 5 5 5 1 GAF domain GAF PF01590.26 ORY74544.1 - 0.009 16.6 0.0 0.25 12.0 0.0 2.7 2 1 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 ORY74544.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Lipase_3 PF01764.25 ORY74546.1 - 8.4e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Zn_clus PF00172.18 ORY74547.1 - 8.2e-07 29.1 10.4 1.7e-06 28.1 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY74547.1 - 1.1e-05 24.6 0.1 2.6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trimer_CC PF08954.11 ORY74547.1 - 0.1 12.2 0.2 0.26 10.9 0.2 1.7 1 0 0 1 1 1 0 Trimerisation motif Rick_17kDa_Anti PF05433.15 ORY74548.1 - 0.017 15.0 2.3 0.059 13.3 2.3 2.0 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF4834 PF16118.5 ORY74548.1 - 0.051 14.5 0.0 0.13 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Hepar_II_III PF07940.13 ORY74549.1 - 1.4e-05 24.8 1.0 2.7e-05 23.9 1.0 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 ORY74549.1 - 0.0048 15.5 4.1 0.0076 14.8 4.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4962) PhnH PF05845.12 ORY74549.1 - 0.031 14.0 0.2 0.054 13.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) Phage_holin_3_6 PF07332.11 ORY74549.1 - 0.052 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PseudoU_synth_1 PF01416.20 ORY74551.1 - 3.8e-23 82.0 0.0 7e-21 74.7 0.0 2.6 1 1 0 1 1 1 1 tRNA pseudouridine synthase DUF4887 PF16228.5 ORY74551.1 - 1.2 9.2 2.7 2.2 8.5 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) MFS_1 PF07690.16 ORY74552.1 - 3.5e-20 72.2 44.9 3.5e-20 72.2 44.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CDP-OH_P_tran_2 PF08009.11 ORY74552.1 - 0.9 9.5 6.1 0.15 11.9 0.6 2.8 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 MFS_1 PF07690.16 ORY74553.1 - 1e-17 64.1 42.8 1e-17 64.1 42.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily UCH PF00443.29 ORY74555.1 - 2.1e-29 102.8 0.0 3.6e-29 102.0 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY74555.1 - 6.1e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ORY74555.1 - 9.9e-06 25.4 0.0 0.0018 18.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UTP25 PF06862.12 ORY74556.1 - 1.6e-174 581.2 0.0 1.8e-174 581.0 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 ORY74556.1 - 0.0039 17.0 0.1 0.086 12.6 0.1 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase PHC2_SAM_assoc PF16616.5 ORY74556.1 - 0.63 10.9 6.9 1.6 9.6 6.9 1.7 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 RRM_1 PF00076.22 ORY74557.1 - 4.1e-09 36.1 0.0 2.5e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRE_C2HC PF07530.11 ORY74557.1 - 0.021 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers RRM_1 PF00076.22 ORY74558.1 - 0.00086 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 ORY74559.1 - 3.5e-08 33.1 0.0 1e-05 25.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAM-associated PF14303.6 ORY74559.1 - 0.41 11.4 4.8 0.7 10.6 4.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SOBP PF15279.6 ORY74559.1 - 5.8 7.4 6.4 8.2 6.9 5.6 1.3 1 1 0 1 1 1 0 Sine oculis-binding protein MMR_HSR1 PF01926.23 ORY74560.1 - 1.4e-16 60.6 0.2 6.8e-15 55.1 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY74560.1 - 3.8e-06 26.9 0.0 0.0024 17.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY74560.1 - 5.9e-06 25.9 0.1 5.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 ORY74560.1 - 0.0051 16.2 0.0 0.0095 15.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 ORY74560.1 - 0.0063 16.6 0.3 0.045 13.8 0.1 2.6 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 ORY74560.1 - 0.063 12.9 0.1 0.66 9.5 0.0 2.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain zf-MYND PF01753.18 ORY74729.1 - 0.27 11.4 10.5 0.61 10.2 10.5 1.6 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.16 ORY74729.1 - 1 9.3 8.0 2.8 7.9 8.0 1.8 1 0 0 1 1 1 0 HIT zinc finger tRNA_int_end_N2 PF12928.7 ORY74730.1 - 3e-16 59.4 0.1 6.1e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 ORY74730.1 - 0.00066 19.3 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Baculo_PEP_C PF04513.12 ORY74731.1 - 0.0045 17.0 4.9 0.15 12.1 0.7 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 ORY74731.1 - 0.0047 16.7 5.9 0.0047 16.7 5.9 1.8 1 1 0 1 1 1 1 Bacterial collagen, middle region BLOC1S3 PF15753.5 ORY74731.1 - 0.11 12.7 0.5 0.14 12.3 0.5 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF1241 PF06840.11 ORY74732.1 - 0.0048 16.6 2.4 0.024 14.3 2.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1241) CRIC_ras_sig PF10534.9 ORY74732.1 - 0.016 15.4 0.8 0.016 15.4 0.8 1.7 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras Phage_Nu1 PF07471.12 ORY74732.1 - 0.28 10.9 2.3 0.42 10.4 2.3 1.2 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 DUF1664 PF07889.12 ORY74732.1 - 0.32 11.0 2.4 2.8 8.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Antimicrobial10 PF08105.11 ORY74732.1 - 1.5 8.9 5.4 0.96 9.6 0.1 2.6 2 0 0 2 2 2 0 Metchnikowin family Baculo_PEP_C PF04513.12 ORY74732.1 - 1.6 8.8 12.5 15 5.6 12.5 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus OPT PF03169.15 ORY74734.1 - 4e-141 471.7 48.4 4.7e-141 471.4 48.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 ORY74735.1 - 7.5e-150 500.5 44.9 8.6e-150 500.3 44.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Kinetochor_Ybp2 PF08568.10 ORY74736.1 - 1.4e-26 93.2 0.0 2.8e-20 72.4 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Synaptobrevin PF00957.21 ORY74737.1 - 3.2e-29 100.5 0.0 4.7e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY74737.1 - 1.5e-21 76.2 0.0 2.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RNA_lig_T4_1 PF09511.10 ORY74738.1 - 1.4e-78 263.7 0.0 1.2e-77 260.7 0.0 2.4 3 0 0 3 3 3 1 RNA ligase tRNA_lig_kinase PF08303.11 ORY74738.1 - 1.5e-24 86.9 0.0 3e-24 86.0 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 ORY74738.1 - 3.8e-24 85.5 0.1 2.1e-23 83.1 0.1 2.1 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain SIL1 PF16782.5 ORY74738.1 - 0.81 8.9 3.7 1 8.5 1.2 2.4 3 0 0 3 3 3 0 Nucleotide exchange factor SIL1 MaoC_dehydratas PF01575.19 ORY74739.1 - 8e-26 90.0 0.0 1.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY74739.1 - 3.1e-07 30.6 0.0 0.00087 19.4 0.0 2.8 3 1 0 3 3 3 2 N-terminal half of MaoC dehydratase Spore_III_AB PF09548.10 ORY74740.1 - 0.025 14.7 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) MatE PF01554.18 ORY74741.1 - 1.6e-55 187.2 19.6 1.9e-29 102.4 5.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 ORY74741.1 - 8.7e-07 29.1 9.8 8.7e-07 29.1 9.8 3.4 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Frag1 PF10277.9 ORY74742.1 - 7.6e-37 127.0 12.0 8.7e-37 126.8 12.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2678 PF10856.8 ORY74742.1 - 0.05 13.5 0.4 0.05 13.5 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) Cation_efflux PF01545.21 ORY74742.1 - 0.055 13.2 9.3 0.012 15.4 4.8 1.9 1 1 1 2 2 2 0 Cation efflux family DUF2070 PF09843.9 ORY74742.1 - 0.06 11.6 3.8 0.071 11.4 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF2085 PF09858.9 ORY74742.1 - 0.24 11.9 7.6 0.066 13.7 2.1 2.6 1 1 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF4079 PF13301.6 ORY74742.1 - 0.46 10.6 5.3 1 9.5 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF373 PF04123.13 ORY74742.1 - 0.88 9.0 4.3 0.35 10.3 1.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Ctr PF04145.15 ORY74742.1 - 1.4 9.6 3.6 4 8.0 1.0 2.8 2 1 0 2 2 2 0 Ctr copper transporter family OPT PF03169.15 ORY74743.1 - 2e-55 188.6 20.5 2.2e-55 188.4 20.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2198 PF09964.9 ORY74743.1 - 1.3 9.1 12.2 12 6.0 0.1 4.2 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2198) DUF1772 PF08592.11 ORY74743.1 - 3.8 7.8 8.9 0.11 12.8 2.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Sugar_tr PF00083.24 ORY74744.1 - 2.9e-28 98.9 28.4 5.5e-17 61.8 9.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY74744.1 - 2.4e-21 76.1 34.5 1.1e-19 70.6 32.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MCM PF00493.23 ORY74745.1 - 2e-99 331.2 0.0 2.9e-99 330.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY74745.1 - 6.9e-38 129.3 0.0 1.2e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY74745.1 - 1.8e-27 95.6 0.6 6.4e-27 93.8 0.6 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 ORY74745.1 - 1.4e-23 83.9 23.6 1.4e-23 83.9 23.6 2.7 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 ORY74745.1 - 4.1e-13 49.8 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY74745.1 - 5.4e-09 35.7 0.1 3.8e-07 29.7 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY74745.1 - 8.9e-06 25.8 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY74745.1 - 0.00012 22.0 0.0 0.0043 16.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY74745.1 - 0.0097 15.6 0.1 0.073 12.8 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Yippee-Mis18 PF03226.14 ORY74745.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Phage_GPD PF05954.11 ORY74745.1 - 0.13 11.5 0.6 0.25 10.6 0.6 1.4 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Cu-oxidase_2 PF07731.14 ORY74747.1 - 5.3e-41 139.6 13.8 3.1e-37 127.4 1.2 3.6 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY74747.1 - 2.5e-38 130.8 10.3 1.6e-35 121.7 2.1 4.3 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY74747.1 - 3.4e-35 121.5 4.1 3.7e-34 118.1 0.9 3.2 3 1 0 3 3 3 1 Multicopper oxidase p450 PF00067.22 ORY74748.1 - 1.8e-61 208.3 0.0 8.2e-61 206.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Synaptobrevin PF00957.21 ORY74749.1 - 3.3e-34 116.6 0.9 3.8e-34 116.4 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 ORY74749.1 - 0.06 14.0 0.0 0.084 13.5 0.0 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor MCU PF04678.13 ORY74749.1 - 0.074 13.2 0.0 0.088 12.9 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Stevor PF17410.2 ORY74749.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.0 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame PRIMA1 PF16101.5 ORY74749.1 - 0.18 11.8 0.3 0.32 11.1 0.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 UPF0258 PF06789.12 ORY74749.1 - 0.26 11.4 1.5 0.35 11.0 1.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) adh_short PF00106.25 ORY74750.1 - 2e-19 69.8 0.0 1.5e-14 53.9 0.1 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY74750.1 - 1e-11 44.8 0.1 4.4e-07 29.7 0.1 2.3 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY74750.1 - 1.2e-08 35.1 0.6 4.1e-08 33.3 0.2 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 ORY74751.1 - 1.8e-18 66.7 0.1 4.7e-17 62.1 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY74751.1 - 1.2e-11 44.6 0.1 1.6e-10 41.0 0.0 2.3 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY74751.1 - 5e-09 36.3 0.4 8.1e-09 35.6 0.4 1.3 1 0 0 1 1 1 1 KR domain Ribosomal_L37 PF08561.10 ORY74752.1 - 6.4e-22 78.3 2.4 9.1e-19 68.1 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Aminotran_4 PF01063.19 ORY74753.1 - 1.6e-22 80.4 0.0 4e-22 79.2 0.0 1.5 1 1 0 1 1 1 1 Amino-transferase class IV ABC_tran PF00005.27 ORY74754.1 - 1.6e-50 171.2 0.0 3.2e-24 86.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 ORY74754.1 - 1.1e-32 113.1 41.8 6e-23 81.4 15.8 3.4 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 ORY74754.1 - 2.2e-15 57.2 3.0 0.003 17.4 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY74754.1 - 6.7e-08 32.6 0.4 0.001 19.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY74754.1 - 1.8e-07 30.8 0.2 0.0059 16.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY74754.1 - 9.5e-07 29.4 0.9 0.039 14.3 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ORY74754.1 - 1.9e-06 27.5 0.0 0.0038 16.7 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ORY74754.1 - 2e-06 27.5 0.1 0.046 13.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 ORY74754.1 - 1.1e-05 25.7 0.1 0.0035 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY74754.1 - 1.5e-05 24.9 0.3 0.04 13.8 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 ORY74754.1 - 5.8e-05 23.3 0.1 0.017 15.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY74754.1 - 7.7e-05 23.2 0.1 0.56 10.7 0.0 2.8 2 1 1 3 3 2 2 AAA domain AAA_22 PF13401.6 ORY74754.1 - 0.00011 22.5 0.1 0.64 10.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORY74754.1 - 0.00017 22.2 0.0 0.47 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY74754.1 - 0.00022 21.0 0.2 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY74754.1 - 0.00065 20.1 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 ORY74754.1 - 0.0034 17.1 0.2 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 ORY74754.1 - 0.0038 17.0 0.0 0.72 9.6 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein TsaE PF02367.17 ORY74754.1 - 0.0038 17.2 0.2 0.59 10.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 ORY74754.1 - 0.0069 16.6 0.2 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY74754.1 - 0.0078 16.3 2.2 2.8 8.1 0.4 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.6 ORY74754.1 - 0.012 16.0 0.1 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 ORY74754.1 - 0.017 14.9 0.9 0.74 9.5 0.3 2.3 2 0 0 2 2 2 0 Cytidylate kinase RNA_helicase PF00910.22 ORY74754.1 - 0.021 15.2 0.0 4.9 7.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 ORY74754.1 - 0.029 14.1 0.0 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY74754.1 - 0.039 14.0 0.1 14 5.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 ORY74754.1 - 0.062 13.4 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 ORY74754.1 - 0.081 12.5 1.9 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ORY74754.1 - 0.11 11.7 0.0 0.67 9.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 ORY74754.1 - 0.11 11.7 0.1 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 ORY74754.1 - 0.15 11.1 0.1 0.49 9.4 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Rad17 PF03215.15 ORY74754.1 - 0.15 12.0 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain ATP-synt_ab PF00006.25 ORY74754.1 - 0.17 11.5 0.0 3.4 7.3 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATPase_2 PF01637.18 ORY74754.1 - 0.19 11.6 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 ORY74754.1 - 0.21 11.3 0.0 5.9 6.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 ORY74754.1 - 0.27 10.7 0.2 18 4.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Pox_A32 PF04665.12 ORY74754.1 - 0.28 10.6 0.6 0.6 9.5 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_17 PF13207.6 ORY74754.1 - 0.48 10.8 1.4 6.1 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.21 ORY74755.1 - 3.2e-79 265.4 0.1 5.7e-79 264.5 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY74755.1 - 3.9e-38 131.6 1.2 1.1e-37 130.1 0.1 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 ORY74755.1 - 8.4e-20 71.5 4.0 1.8e-18 67.2 0.2 3.3 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ORY74755.1 - 1.1e-16 60.9 0.9 2.4e-16 59.8 0.9 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 ORY74755.1 - 1.6e-10 41.2 0.0 3.5e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I DUF5473 PF17567.2 ORY74755.1 - 0.00031 21.0 0.0 0.00073 19.8 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5473) AAA_27 PF13514.6 ORY74755.1 - 0.067 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mre11_DNA_bind PF04152.14 ORY74755.1 - 0.077 13.3 0.1 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 Mre11 DNA-binding presumed domain Tetraspanin PF00335.20 ORY74756.1 - 0.00054 19.7 16.3 0.002 17.9 16.3 1.9 1 1 0 1 1 1 1 Tetraspanin family CitMHS PF03600.16 ORY74756.1 - 0.025 13.8 8.3 0.05 12.8 8.3 1.6 1 1 0 1 1 1 0 Citrate transporter DUF4231 PF14015.6 ORY74756.1 - 0.26 11.8 3.1 0.55 10.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 ORY74756.1 - 0.74 8.5 6.7 0.2 10.4 2.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4234 PF14018.6 ORY74756.1 - 2.6 8.2 7.1 4.2 7.6 2.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) SieB PF14163.6 ORY74756.1 - 2.9 7.4 5.1 51 3.3 1.1 3.0 3 0 0 3 3 3 0 Super-infection exclusion protein B Cyclin_N PF00134.23 ORY74757.1 - 1.5e-41 141.1 0.1 2.8e-41 140.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY74757.1 - 4.2e-30 104.3 0.0 2.6e-29 101.7 0.0 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain PAPA-1 PF04795.12 ORY74758.1 - 2.2e-19 70.0 0.0 2.2e-19 70.0 0.0 2.8 3 0 0 3 3 3 1 PAPA-1-like conserved region PRIMA1 PF16101.5 ORY74759.1 - 1.2 9.2 7.8 2.2 8.3 7.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Baculo_LEF-2 PF03041.14 ORY74762.1 - 0.061 13.0 0.1 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 lef-2 Lipase_3 PF01764.25 ORY74764.1 - 1.1e-17 64.2 0.0 1.7e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY74764.1 - 0.081 13.5 1.5 0.41 11.2 0.0 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY74764.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Insulin_TMD PF17870.1 ORY74764.1 - 0.23 11.5 2.9 0.52 10.4 2.9 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Peptidase_S49 PF01343.18 ORY74767.1 - 1.9e-40 138.3 0.0 3.9e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 Peptidase_S8 PF00082.22 ORY74767.1 - 0.0029 16.9 0.0 0.0044 16.3 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Histone_H2A_C PF16211.5 ORY74768.1 - 0.047 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 C-terminus of histone H2A EBP50_C PF09007.11 ORY74768.1 - 0.13 13.3 0.0 0.22 12.5 0.0 1.4 1 0 0 1 1 1 0 EBP50, C-terminal ArAE_2_N PF10337.9 ORY74769.1 - 6e-60 203.6 0.0 1.1e-59 202.8 0.0 1.3 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 ORY74769.1 - 5.1e-42 144.3 0.1 1.9e-40 139.2 0.1 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY74769.1 - 4.4e-07 30.1 13.2 4.4e-07 30.1 13.2 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like RSN1_7TM PF02714.15 ORY74770.1 - 1.4e-68 231.2 22.1 2.3e-68 230.5 22.1 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY74770.1 - 5.5e-33 114.7 0.0 8e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY74770.1 - 1.3e-30 106.3 0.9 1.3e-30 106.3 0.9 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport RRM_1 PF00076.22 ORY74771.1 - 7.2e-16 57.8 0.0 1.1e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 ORY74771.1 - 0.0003 20.7 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 RL domain RRM_5 PF13893.6 ORY74771.1 - 0.0049 16.5 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 ORY74771.1 - 0.045 14.0 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Limkain-b1 PF11608.8 ORY74771.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 Limkain b1 DUF4188 PF13826.6 ORY74772.1 - 3.2e-26 92.0 0.0 4.3e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) DUF3986 PF13143.6 ORY74772.1 - 0.0089 17.0 0.2 0.015 16.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3986) Dehydratase_hem PF13816.6 ORY74772.1 - 0.035 13.5 0.0 0.049 13.0 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase PCRF PF03462.18 ORY74773.1 - 2.2e-46 158.2 0.2 1.8e-45 155.2 0.0 2.1 2 1 0 2 2 2 1 PCRF domain RF-1 PF00472.20 ORY74773.1 - 3.6e-35 120.4 3.5 8.4e-35 119.2 3.5 1.6 1 0 0 1 1 1 1 RF-1 domain MoCF_biosynth PF00994.24 ORY74773.1 - 0.041 13.5 0.2 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Probable molybdopterin binding domain NAC PF01849.18 ORY74774.1 - 7e-21 74.0 0.2 1.8e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 NAC domain TssC PF17541.2 ORY74774.1 - 0.16 10.7 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Snurportin1 PF11538.8 ORY74777.1 - 0.0019 18.3 0.8 0.0039 17.3 0.2 1.8 2 0 0 2 2 2 1 Snurportin1 LSM PF01423.22 ORY74778.1 - 2.7e-15 55.8 0.3 2.9e-15 55.7 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY74778.1 - 1.8e-05 24.8 0.1 1.9e-05 24.7 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ORY74778.1 - 0.027 14.6 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain AA_permease_2 PF13520.6 ORY74779.1 - 3.3e-29 102.0 41.8 4.2e-29 101.6 41.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY74779.1 - 1.6e-16 60.0 36.7 2.2e-16 59.5 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M28 PF04389.17 ORY74780.1 - 1.4e-28 99.9 0.0 2.3e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY74780.1 - 2.4e-05 24.1 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ORY74780.1 - 0.0082 15.6 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M42 PF05343.14 ORY74780.1 - 0.12 11.3 0.0 0.26 10.3 0.0 1.4 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase EB PF01683.18 ORY74781.1 - 0.003 17.8 4.5 0.014 15.7 0.6 2.3 1 1 1 2 2 2 2 EB module GTP_EFTU PF00009.27 ORY74782.1 - 8e-45 152.8 0.0 1.8e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY74782.1 - 1.4e-33 115.6 2.5 1.8e-33 115.2 0.1 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY74782.1 - 2.7e-10 40.5 0.2 1.1e-09 38.5 0.2 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY74782.1 - 0.00046 20.2 0.8 0.0032 17.5 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase eIF3_subunit PF08597.10 ORY74782.1 - 0.039 13.9 7.7 0.076 12.9 7.7 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ABC_tran PF00005.27 ORY74783.1 - 8.4e-51 172.1 0.0 7.9e-28 97.7 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY74783.1 - 7.2e-16 58.9 2.4 0.0014 18.5 0.5 4.3 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY74783.1 - 5.7e-13 48.8 0.3 0.00043 19.8 0.0 3.7 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY74783.1 - 3.1e-08 34.3 0.3 0.0039 17.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 ORY74783.1 - 1.2e-06 28.1 0.4 0.049 13.4 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY74783.1 - 1.2e-05 25.3 0.2 0.055 13.4 0.1 2.6 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY74783.1 - 1.5e-05 25.0 0.0 0.0049 16.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY74783.1 - 2.3e-05 24.3 0.0 0.07 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Chromo PF00385.24 ORY74783.1 - 3e-05 23.8 0.0 7.1e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 ORY74783.1 - 3.4e-05 24.3 0.0 5.6 7.4 0.0 4.0 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 ORY74783.1 - 4.9e-05 22.4 0.3 0.1 11.5 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ORY74783.1 - 0.00011 22.4 0.4 1.4 9.2 0.1 3.8 4 1 0 4 4 2 2 AAA domain AAA_18 PF13238.6 ORY74783.1 - 0.00022 21.8 0.0 0.99 10.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORY74783.1 - 0.00029 21.1 0.0 0.47 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORY74783.1 - 0.00048 20.3 0.0 2.3 8.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain 4HB PF17947.1 ORY74783.1 - 0.00057 19.9 0.5 0.0016 18.5 0.5 1.8 1 0 0 1 1 1 1 Four helical bundle domain RNA_helicase PF00910.22 ORY74783.1 - 0.00069 20.0 0.0 2.5 8.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Rad17 PF03215.15 ORY74783.1 - 0.0024 17.8 0.0 2.9 7.8 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Dynamin_N PF00350.23 ORY74783.1 - 0.0025 17.9 0.0 0.31 11.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 ORY74783.1 - 0.0034 17.8 3.2 0.59 10.5 0.0 3.9 3 1 2 5 5 4 1 AAA ATPase domain NB-ARC PF00931.22 ORY74783.1 - 0.004 16.4 0.0 0.6 9.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 ORY74783.1 - 0.0056 16.7 0.0 5.2 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORY74783.1 - 0.0072 15.5 0.1 5.2 6.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY74783.1 - 0.0077 15.8 0.0 0.76 9.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 ORY74783.1 - 0.0079 16.4 0.2 21 5.4 0.0 4.3 4 1 0 4 4 3 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ORY74783.1 - 0.015 15.0 0.0 1.1 8.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.12 ORY74783.1 - 0.016 14.5 0.2 5.1 6.3 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.19 ORY74783.1 - 0.022 14.3 0.0 6 6.4 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 ORY74783.1 - 0.028 13.8 0.1 5.8 6.2 0.0 3.0 4 0 0 4 4 2 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 ORY74783.1 - 0.034 14.4 0.1 9.4 6.5 0.0 3.1 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 ORY74783.1 - 0.035 14.0 0.0 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 ORY74783.1 - 0.037 13.7 0.0 1.7 8.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORY74783.1 - 0.048 13.7 0.2 1.3 9.1 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain PduV-EutP PF10662.9 ORY74783.1 - 0.05 13.4 0.1 15 5.3 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 ORY74783.1 - 0.055 12.7 0.0 4 6.6 0.0 2.3 2 0 0 2 2 2 0 Septin PRK PF00485.18 ORY74783.1 - 0.074 12.8 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_27 PF13514.6 ORY74783.1 - 0.08 12.5 0.1 10 5.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 ORY74783.1 - 0.08 12.8 0.0 16 5.3 0.0 2.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 ORY74783.1 - 0.084 11.7 0.1 1.8 7.3 0.0 2.9 3 1 0 3 3 3 0 Predicted ATPase of the ABC class ubiquitin PF00240.23 ORY74784.1 - 1.5e-24 85.5 0.0 3.1e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY74784.1 - 9.7e-10 38.1 0.0 2.4e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Prok-RING_4 PF14447.6 ORY74784.1 - 0.00043 20.1 1.5 0.001 18.9 1.5 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY74784.1 - 0.0012 18.8 2.5 0.0021 18.0 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY74784.1 - 0.0019 18.0 1.6 0.0033 17.2 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY74784.1 - 0.0032 17.5 0.9 0.0079 16.2 0.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Ubiquitin_2 PF14560.6 ORY74784.1 - 0.048 14.1 0.0 0.26 11.8 0.0 2.2 2 1 0 2 2 1 0 Ubiquitin-like domain zf-C3HC4_2 PF13923.6 ORY74784.1 - 0.061 13.2 1.0 0.095 12.6 0.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY74784.1 - 0.075 12.9 3.0 0.14 12.1 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 ORY74784.1 - 0.23 11.6 0.9 0.49 10.6 0.9 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-RING_2 PF13639.6 ORY74784.1 - 0.76 10.2 2.5 1.7 9.0 2.5 1.6 1 0 0 1 1 1 0 Ring finger domain Cyt-b5 PF00173.28 ORY74786.1 - 3e-20 72.2 0.1 6.8e-20 71.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ORY74786.1 - 2.3e-13 50.7 14.4 2.3e-13 50.7 14.4 2.3 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily ECF_trnsprt PF12822.7 ORY74786.1 - 0.0015 18.7 1.8 0.0023 18.0 1.8 1.2 1 0 0 1 1 1 1 ECF transporter, substrate-specific component DUF1772 PF08592.11 ORY74786.1 - 0.2 12.0 3.2 0.38 11.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) TBCA PF02970.16 ORY74787.1 - 4.8e-26 90.9 1.2 6.1e-26 90.6 1.2 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A LPD23 PF18838.1 ORY74787.1 - 0.026 14.3 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 DUF2117 PF09890.9 ORY74787.1 - 0.097 12.1 0.5 0.11 11.9 0.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) Spc7 PF08317.11 ORY74787.1 - 0.2 10.5 3.8 0.21 10.5 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Rad60-SLD_2 PF13881.6 ORY74788.1 - 2.5e-11 43.6 0.0 7.4e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY74788.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin family SnoaL_2 PF12680.7 ORY74789.1 - 0.037 14.7 0.0 0.059 14.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain G-alpha PF00503.20 ORY74790.1 - 3.9e-98 328.9 0.0 4.9e-98 328.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY74790.1 - 3.3e-14 52.7 0.1 3.3e-09 36.4 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY74790.1 - 3.1e-06 26.7 0.3 0.00019 20.9 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY74790.1 - 0.0058 16.8 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY74790.1 - 0.066 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AdoHcyase PF05221.17 ORY74792.1 - 6.8e-133 442.4 0.0 1.4e-72 244.3 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ORY74792.1 - 2.4e-85 284.6 0.4 3.7e-85 283.9 0.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY74792.1 - 1.1e-06 28.1 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORY74792.1 - 1.9e-05 24.3 0.0 4e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ORY74792.1 - 0.00052 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 ORY74792.1 - 0.12 13.0 0.1 0.29 11.7 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PGI PF00342.19 ORY74794.1 - 4.3e-230 764.4 0.6 4.9e-230 764.2 0.6 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4965 PF16335.5 ORY74795.1 - 2.3e-51 173.9 0.0 3.6e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 ORY74795.1 - 2.2e-49 168.3 0.2 3.1e-49 167.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 ORY74795.1 - 1.4e-39 136.2 0.2 6e-39 134.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 ORY74795.1 - 2.1e-05 24.0 0.0 6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Pyr_redox_2 PF07992.14 ORY74796.1 - 8.9e-50 169.6 0.1 1.1e-49 169.3 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY74796.1 - 6.5e-18 65.1 0.1 4.2e-15 56.1 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY74796.1 - 5.9e-16 58.6 0.1 3.2e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY74796.1 - 8.8e-06 25.1 0.0 9.6e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORY74796.1 - 3.6e-05 23.0 1.0 0.0041 16.3 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ORY74796.1 - 5.3e-05 22.7 0.1 0.025 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 ORY74796.1 - 0.00025 20.2 2.0 0.011 14.9 0.1 3.0 4 0 0 4 4 4 1 Glucose inhibited division protein A DAO PF01266.24 ORY74796.1 - 0.0017 18.0 1.0 0.34 10.4 0.3 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY74796.1 - 0.0024 17.2 0.2 0.041 13.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ORY74796.1 - 0.0059 16.8 0.4 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY74796.1 - 0.024 13.4 0.2 0.058 12.1 0.2 1.6 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 ORY74796.1 - 0.025 13.4 0.1 0.068 12.0 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 ORY74796.1 - 0.04 13.1 0.0 4.6 6.3 0.1 3.2 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 ORY74796.1 - 0.13 12.7 0.2 10 6.6 0.0 2.8 2 2 1 3 3 3 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 ORY74796.1 - 0.16 12.0 0.0 9.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ILVD_EDD PF00920.21 ORY74797.1 - 1.9e-205 683.4 0.8 2.2e-205 683.2 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family ubiquitin PF00240.23 ORY74983.1 - 5.2e-23 80.6 0.7 5.9e-23 80.4 0.7 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY74983.1 - 2.5e-11 43.2 0.1 2.8e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY74983.1 - 0.0021 18.5 0.3 0.0055 17.1 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY74983.1 - 0.024 15.0 0.3 0.029 14.7 0.3 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY74983.1 - 0.026 14.5 0.0 0.03 14.2 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Mo-co_dimer PF03404.16 ORY74984.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Ala_racemase_N PF01168.20 ORY74985.1 - 4.5e-15 55.9 0.0 4.6e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Aminotran_1_2 PF00155.21 ORY74986.1 - 5e-27 95.0 0.0 6.2e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORY74986.1 - 1.3e-14 53.8 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 ORY74986.1 - 0.21 10.1 0.0 0.31 9.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Exo_endo_phos PF03372.23 ORY74987.1 - 7.4e-20 71.5 0.1 1.5e-19 70.4 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 ORY74987.1 - 2.2e-05 24.4 6.2 0.00042 20.4 6.2 2.4 1 1 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 ORY74987.1 - 0.0001 22.1 0.0 0.0076 16.1 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Spuma_A9PTase PF03539.14 ORY74987.1 - 0.08 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) DHHC PF01529.20 ORY74988.1 - 9.7e-15 54.9 5.7 1.6e-14 54.1 0.6 2.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase CSD PF00313.22 ORY74989.1 - 2.7e-22 78.4 0.9 1.5e-10 40.8 0.1 2.3 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain DPBB_1 PF03330.18 ORY74991.1 - 2.7e-08 34.0 0.4 3e-07 30.6 0.4 2.0 1 1 0 1 1 1 1 Lytic transglycolase Ribosomal_L19e PF01280.20 ORY74993.1 - 4.2e-61 205.2 9.9 4.2e-61 205.2 9.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e DUF2202 PF09968.9 ORY74993.1 - 0.033 14.0 0.3 0.059 13.2 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) DPBB_1 PF03330.18 ORY74995.1 - 8.9e-08 32.3 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY74995.1 - 7.2e-06 25.8 0.1 9.5e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family CN_hydrolase PF00795.22 ORY74996.1 - 2.3e-54 184.5 0.0 2.5e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF383 PF04063.14 ORY74997.1 - 2.5e-57 193.7 0.1 5.9e-56 189.2 0.0 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF383) DUF384 PF04064.13 ORY74997.1 - 2.1e-10 40.3 0.2 5.7e-10 38.9 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Cnd1 PF12717.7 ORY74997.1 - 0.0013 18.8 1.2 0.13 12.3 0.9 2.2 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Trns_repr_metal PF02583.17 ORY74997.1 - 0.029 14.7 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Proteasom_PSMB PF10508.9 ORY74997.1 - 0.072 11.6 0.4 1.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit AICARFT_IMPCHas PF01808.18 ORY74998.1 - 1.8e-90 303.4 0.3 2.4e-90 303.0 0.3 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ORY74998.1 - 3e-22 78.6 0.0 6.6e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Ribosomal_S11 PF00411.19 ORY74998.1 - 0.038 14.4 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S11 DUF2937 PF11157.8 ORY74998.1 - 0.11 12.2 0.7 0.2 11.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Opi1 PF08618.10 ORY74999.1 - 1.7e-87 294.4 10.2 1.3e-70 238.8 8.5 3.6 3 1 1 4 4 4 2 Transcription factor Opi1 MFS_1 PF07690.16 ORY75000.1 - 6.2e-35 120.8 32.3 6.2e-35 120.8 32.3 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sds3 PF08598.11 ORY75001.1 - 5.6e-08 33.1 0.0 3.7e-07 30.4 0.0 2.2 2 1 0 2 2 2 1 Sds3-like OrfB_IS605 PF01385.19 ORY75001.1 - 0.014 15.6 1.6 0.036 14.3 0.1 2.0 2 0 0 2 2 2 0 Probable transposase DASH_Hsk3 PF08227.11 ORY75002.1 - 8.8e-14 51.6 6.1 1.1e-13 51.3 6.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like DUF3552 PF12072.8 ORY75002.1 - 0.015 14.7 0.8 0.018 14.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DNA_pol3_alpha PF07733.12 ORY75002.1 - 0.015 14.9 0.0 0.016 14.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain Csm1_N PF18504.1 ORY75002.1 - 0.016 15.5 2.2 0.021 15.1 2.2 1.1 1 0 0 1 1 1 0 Csm1 N-terminal domain DivIC PF04977.15 ORY75002.1 - 0.024 14.4 0.6 0.031 14.0 0.6 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF919 PF06034.11 ORY75002.1 - 0.059 13.2 0.3 0.072 12.9 0.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) SlyX PF04102.12 ORY75002.1 - 0.17 12.5 4.4 0.44 11.2 4.5 1.6 1 1 1 2 2 2 0 SlyX MFS_1 PF07690.16 ORY75003.1 - 2.8e-34 118.6 48.9 1.1e-33 116.7 41.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TM231 PF10149.9 ORY75003.1 - 0.19 11.0 3.7 1.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Transmembrane protein 231 SecE PF00584.20 ORY75003.1 - 1.9 8.5 5.2 19 5.3 0.0 3.4 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex DUF4231 PF14015.6 ORY75003.1 - 5.6 7.5 7.7 11 6.6 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) PDZ_5 PF17817.1 ORY75004.1 - 0.16 12.3 1.6 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 PDZ domain CENP-B_dimeris PF09026.10 ORY75004.1 - 1.8 9.0 6.1 3.3 8.2 6.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.11 ORY75004.1 - 2.3 6.2 15.3 2.5 6.1 8.8 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen HD_4 PF13328.6 ORY75006.1 - 5.4e-13 49.0 0.0 8.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 HD domain HD PF01966.22 ORY75006.1 - 0.026 14.7 0.1 0.062 13.5 0.1 1.7 1 1 0 1 1 1 0 HD domain MKT1_C PF12246.8 ORY75007.1 - 1.2e-78 263.7 0.0 4.1e-78 261.9 0.0 1.8 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 ORY75007.1 - 9.2e-22 77.2 0.0 3.4e-21 75.4 0.0 2.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 ORY75007.1 - 6.9e-11 42.5 0.0 1.6e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Mito_carr PF00153.27 ORY75008.1 - 7e-63 208.6 4.8 1.4e-21 76.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Chlorosome_CsmC PF11098.8 ORY75008.1 - 0.0031 17.5 0.3 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Chlorosome envelope protein C Serine_protease PF18405.1 ORY75008.1 - 0.53 9.4 6.3 1.9 7.6 0.3 3.1 2 1 1 3 3 3 0 Gammaproteobacterial serine protease Pribosyltran PF00156.27 ORY75009.1 - 4.9e-05 22.9 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ArfGap PF01412.18 ORY75010.1 - 1.6e-39 134.6 0.5 3.1e-39 133.7 0.5 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 ORY75010.1 - 7.6e-11 42.5 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 PH domain BAR_3 PF16746.5 ORY75010.1 - 7.3e-06 25.9 1.3 0.00016 21.5 0.2 2.4 2 0 0 2 2 2 1 BAR domain of APPL family PH_9 PF15410.6 ORY75010.1 - 0.076 13.4 0.2 0.7 10.3 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain EMA PF02488.15 ORY75010.1 - 0.086 12.5 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Merozoite Antigen DUF5082 PF16888.5 ORY75010.1 - 1.3 9.3 5.3 0.26 11.6 0.2 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF615 PF04751.14 ORY75010.1 - 7 6.6 12.6 1.6 8.7 7.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF615) PH PF00169.29 ORY75011.1 - 2.8e-06 27.8 0.0 6.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY75011.1 - 0.0012 19.3 0.0 0.0041 17.5 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Cofilin_ADF PF00241.20 ORY75011.1 - 0.0064 16.3 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Hamartin PF04388.12 ORY75011.1 - 0.44 9.1 22.2 0.67 8.5 22.2 1.4 1 0 0 1 1 1 0 Hamartin protein FAM70 PF14967.6 ORY75011.1 - 3.8 6.9 4.5 7 6.0 4.5 1.4 1 0 0 1 1 1 0 FAM70 protein Methyltransf_24 PF13578.6 ORY75012.1 - 3.1e-10 41.0 0.0 4.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ran_BP1 PF00638.18 ORY75014.1 - 3.4e-13 49.9 0.0 1.2e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 RanBP1 domain DUF3506 PF12014.8 ORY75015.1 - 2.8e-10 40.4 0.0 2.1e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 ORY75015.1 - 1.6e-08 34.3 0.1 2.8e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY75015.1 - 4.4e-05 23.2 0.1 8.9e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY75015.1 - 0.00047 20.0 0.0 0.00079 19.3 0.0 1.3 1 0 0 1 1 1 1 F-box NUDIX PF00293.28 ORY75016.1 - 1e-13 51.4 0.8 2.9e-13 50.0 0.1 1.9 2 0 0 2 2 2 1 NUDIX domain PAS_4 PF08448.10 ORY75016.1 - 0.081 13.2 0.0 0.98 9.7 0.0 2.2 2 0 0 2 2 2 0 PAS fold PBP PF01161.20 ORY75017.1 - 2.1e-14 54.0 0.3 4.7e-14 52.8 0.3 1.5 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein START PF01852.19 ORY75018.1 - 5.2e-10 39.1 0.0 7e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 START domain PH_10 PF15411.6 ORY75019.1 - 8.4e-23 81.0 0.0 1.6e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 ORY75019.1 - 6.9e-05 23.2 0.0 0.00016 22.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 ORY75019.1 - 0.00054 20.2 5.2 0.0011 19.3 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY75019.1 - 0.0023 17.9 2.3 0.0062 16.5 2.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger VWA_3 PF13768.6 ORY75019.1 - 0.0083 16.1 0.0 0.037 14.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-C3HC4_2 PF13923.6 ORY75019.1 - 0.3 11.0 2.0 0.87 9.5 2.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY75019.1 - 0.44 10.6 4.3 0.9 9.6 4.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain PRCC PF10253.9 ORY75019.1 - 1.2 9.9 8.9 0.92 10.3 2.1 2.8 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Zn_ribbon_17 PF17120.5 ORY75019.1 - 2.2 8.0 4.0 4.7 6.9 4.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORY75019.1 - 4.1 7.2 6.1 11 5.9 6.1 1.8 1 0 0 1 1 1 0 RING-like zinc finger Kinesin PF00225.23 ORY75020.1 - 9.4e-110 366.6 0.0 1e-109 366.5 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY75020.1 - 1.4e-21 77.0 0.0 3.2e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding Ysc84 PF04366.12 ORY75021.1 - 2.7e-39 133.8 0.0 4.6e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ig_5 PF16681.5 ORY75022.1 - 0.0083 16.5 0.9 0.047 14.1 0.1 2.4 2 0 0 2 2 2 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain F-box-like PF12937.7 ORY75022.1 - 0.012 15.5 0.1 0.029 14.3 0.1 1.7 1 0 0 1 1 1 0 F-box-like zf-C4pol PF14260.6 ORY75022.1 - 0.091 13.2 0.3 0.27 11.7 0.3 1.8 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta PH PF00169.29 ORY75023.1 - 9.2e-08 32.5 1.0 1.2e-07 32.1 0.2 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 ORY75023.1 - 7.3e-05 23.1 1.0 0.00062 20.2 1.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 ORY75023.1 - 0.13 12.7 0.4 0.75 10.2 0.4 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain DUF1199 PF06712.11 ORY75023.1 - 0.39 10.8 3.3 0.27 11.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) DUF2370 PF10176.9 ORY75024.1 - 3.5e-71 239.5 0.0 1.9e-70 237.0 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) IATP PF04568.12 ORY75025.1 - 8.3 6.9 7.4 23 5.5 7.4 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF4505 PF14956.6 ORY75026.1 - 2.4e-27 95.8 0.0 1.1e-26 93.7 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4505) DEAD PF00270.29 ORY75027.1 - 6.4e-46 156.3 0.0 1.1e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY75027.1 - 3.4e-31 107.9 0.0 6.4e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY75027.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY75027.1 - 0.23 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Asp PF00026.23 ORY75028.1 - 3.7e-66 223.7 0.0 4.6e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY75028.1 - 1.6e-11 44.8 6.1 1.6e-07 31.7 0.3 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Flavin_Reduct PF01613.18 ORY75029.1 - 1e-20 74.3 0.1 1.5e-20 73.8 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_S13 PF00416.22 ORY75030.1 - 8.1e-54 181.4 1.3 9.4e-54 181.2 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 ORY75030.1 - 0.01 14.6 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 ORY75030.1 - 0.058 13.6 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif Syntaxin-6_N PF09177.11 ORY75030.1 - 0.097 13.2 0.0 0.21 12.2 0.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal PHF12_MRG_bd PF16737.5 ORY75030.1 - 0.1 12.3 0.2 0.24 11.1 0.1 1.6 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain Asp PF00026.23 ORY75031.1 - 1.7e-46 159.1 0.0 9.8e-41 140.2 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY75031.1 - 1.3e-12 48.3 2.8 4.3e-06 27.1 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY75031.1 - 0.00097 19.7 0.2 0.0067 17.0 0.1 2.3 2 1 0 2 2 2 1 Aspartyl protease MFS_1 PF07690.16 ORY75032.1 - 4e-30 104.9 47.5 1.6e-29 102.9 40.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_US9 PF06072.11 ORY75032.1 - 0.016 15.1 0.1 0.016 15.1 0.1 3.4 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 TRI12 PF06609.13 ORY75032.1 - 0.16 10.4 10.2 0.027 12.9 6.6 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Sds3 PF08598.11 ORY75033.1 - 1.3e-07 31.9 0.6 1.3e-07 31.9 0.6 1.8 2 0 0 2 2 2 1 Sds3-like GlutR_dimer PF00745.20 ORY75034.1 - 0.051 14.0 3.3 0.065 13.7 3.3 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Phage_Arf PF17585.2 ORY75034.1 - 0.13 12.2 0.5 0.21 11.5 0.5 1.3 1 0 0 1 1 1 0 Accessory recombination function protein DUF1542 PF07564.11 ORY75034.1 - 0.58 10.3 5.8 0.77 9.9 5.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Forkhead PF00250.18 ORY75035.1 - 5.3e-35 119.5 0.0 6e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain adh_short PF00106.25 ORY75037.1 - 1e-40 139.3 0.9 2.3e-40 138.1 0.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY75037.1 - 2.7e-40 138.4 0.4 5.1e-40 137.5 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY75037.1 - 2.9e-14 53.4 0.1 4.1e-14 52.9 0.1 1.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY75037.1 - 3.4e-05 23.1 0.0 4.9e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORY75037.1 - 0.00064 19.8 0.1 0.0013 18.8 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 ORY75037.1 - 0.011 15.3 0.1 0.049 13.1 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 ORY75037.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain HSP70 PF00012.20 ORY75038.1 - 2.5e-158 528.0 8.3 5.4e-158 526.9 8.3 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY75038.1 - 2.9e-10 39.5 0.3 2.9e-10 39.5 0.3 1.5 2 0 0 2 2 2 1 MreB/Mbl protein Mago_nashi PF02792.14 ORY75038.1 - 0.02 15.0 0.7 0.42 10.7 0.2 2.3 2 0 0 2 2 2 0 Mago nashi protein StbA PF06406.11 ORY75038.1 - 0.057 12.6 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 StbA protein MmcB-like PF06319.12 ORY75038.1 - 0.11 12.2 0.3 4.9 6.8 0.0 2.4 2 0 0 2 2 2 0 DNA repair protein MmcB-like GlutR_dimer PF00745.20 ORY75038.1 - 0.93 10.0 6.0 0.81 10.2 3.5 2.2 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF1542 PF07564.11 ORY75038.1 - 2.7 8.2 10.7 0.95 9.6 7.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF406 PF04175.12 ORY75038.1 - 3.8 8.1 7.0 2.3 8.7 1.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF406) Voltage_CLC PF00654.20 ORY75039.1 - 1.4e-88 297.6 24.0 1.4e-88 297.6 24.0 1.9 2 1 0 2 2 2 1 Voltage gated chloride channel ER_lumen_recept PF00810.18 ORY75040.1 - 1.1e-54 185.3 4.2 1.7e-54 184.7 4.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 ORY75040.1 - 0.0018 18.0 7.8 0.23 11.3 0.3 4.1 2 1 2 4 4 4 2 PQ loop repeat ubiquitin PF00240.23 ORY75041.1 - 2.7e-07 30.2 0.5 1.4e-06 27.9 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY75041.1 - 7.1e-06 26.4 0.2 3.5e-05 24.2 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain RAWUL PF16207.5 ORY75041.1 - 0.0075 16.9 0.0 0.0092 16.6 0.0 1.1 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD PF11976.8 ORY75041.1 - 0.018 14.8 0.3 0.12 12.2 0.3 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 ORY75041.1 - 0.048 13.7 0.2 0.99 9.5 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain PI3K_rbd PF00794.18 ORY75041.1 - 0.099 12.8 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain zf-CCCH_2 PF14608.6 ORY75042.1 - 4.3e-06 27.0 32.9 0.014 15.8 2.1 4.4 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger Ribosomal_S2 PF00318.20 ORY75043.1 - 5.5e-51 172.8 0.0 1.1e-48 165.4 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S2 DUF4603 PF15376.6 ORY75043.1 - 0.0045 14.5 4.5 0.0073 13.8 4.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) IGPS PF00218.21 ORY75044.1 - 1.5e-85 286.4 0.0 3.5e-85 285.2 0.0 1.6 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 ORY75044.1 - 1.3e-49 168.6 0.0 1.1e-40 139.5 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 ORY75044.1 - 4.1e-46 157.1 0.0 7e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY75044.1 - 1.8e-07 31.1 0.0 4.8e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 ORY75044.1 - 3e-05 23.9 0.9 0.00082 19.2 0.3 2.9 3 1 1 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain PDZ PF00595.24 ORY75044.1 - 0.069 13.5 0.6 0.79 10.1 0.2 2.4 2 0 0 2 2 2 0 PDZ domain Apc13p PF05839.11 ORY75045.1 - 0.13 12.4 0.7 0.38 11.0 0.1 2.2 2 0 0 2 2 2 0 Apc13p protein SNF2_N PF00176.23 ORY75046.1 - 5.1e-62 209.6 0.0 7.2e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 ORY75046.1 - 5.9e-19 67.8 0.0 1.3e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 ORY75046.1 - 3.3e-16 59.6 0.0 6.9e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 ORY75046.1 - 9.8e-09 35.4 2.5 1.8e-08 34.6 2.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY75046.1 - 3.6e-08 33.0 2.3 7.9e-08 31.9 2.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY75046.1 - 1.5e-06 28.4 1.7 4.3e-06 26.9 1.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY75046.1 - 2.4e-06 27.3 0.6 4e-06 26.6 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY75046.1 - 7.1e-06 25.8 3.9 1.3e-05 24.9 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY75046.1 - 1.4e-05 24.8 4.8 2.7e-05 23.9 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY75046.1 - 0.00025 20.9 1.1 0.00048 20.0 1.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 ORY75046.1 - 0.00075 19.5 0.0 0.0032 17.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 ORY75046.1 - 0.00092 19.2 4.2 0.0022 18.0 4.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger DEAD PF00270.29 ORY75046.1 - 0.016 15.0 0.0 0.069 12.9 0.0 2.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase zf-ANAPC11 PF12861.7 ORY75046.1 - 0.056 13.5 0.2 0.44 10.6 0.3 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY75046.1 - 0.092 12.9 1.3 0.2 11.8 1.3 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORY75046.1 - 0.14 12.1 1.5 0.25 11.3 1.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 HEPN_AbiU2 PF18734.1 ORY75046.1 - 0.27 10.7 0.5 0.77 9.2 0.1 2.0 3 0 0 3 3 3 0 AbiU2 Acetyltransf_1 PF00583.25 ORY75047.1 - 2.3e-14 53.6 0.0 3.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY75047.1 - 2.6e-11 43.6 0.0 3.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY75047.1 - 1.5e-08 34.9 0.0 2.3e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY75047.1 - 1.2e-07 31.6 0.0 2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY75047.1 - 0.007 17.0 0.1 0.0094 16.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Arch_fla_DE PF04659.13 ORY75047.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal flagella protein Acetyltransf_15 PF17013.5 ORY75047.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 ORY75047.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase MOZART1 PF12554.8 ORY75048.1 - 2.5e-22 78.4 0.2 3e-22 78.1 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated CPSase_L_D2 PF02786.17 ORY75049.1 - 4e-113 376.1 0.3 4.3e-83 278.0 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 ORY75049.1 - 5.3e-45 152.4 0.0 1.3e-44 151.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 ORY75049.1 - 4.5e-44 150.1 0.0 1.6e-43 148.3 0.0 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 ORY75049.1 - 1.2e-41 141.9 0.0 2.8e-41 140.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.28 ORY75049.1 - 2.8e-41 141.4 0.0 7.4e-41 140.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace PF00185.24 ORY75049.1 - 5.2e-33 114.3 0.0 1.1e-32 113.3 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 ORY75049.1 - 3.4e-20 72.0 0.0 2.4e-19 69.3 0.0 2.5 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 ORY75049.1 - 2.4e-17 63.1 0.4 2e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY75049.1 - 2.2e-14 53.4 0.1 1.2e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORY75049.1 - 1.3e-09 37.9 0.1 0.00033 20.4 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 ORY75049.1 - 4.7e-06 26.5 0.0 0.029 14.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 ATP-grasp_3 PF02655.14 ORY75049.1 - 0.0003 20.9 0.1 0.4 10.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain DUF3684 PF12449.8 ORY75050.1 - 0 1115.5 0.0 0 1115.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 ORY75050.1 - 0.00063 19.6 0.0 0.0031 17.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CUE PF02845.16 ORY75050.1 - 0.076 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 CUE domain Rotamase_3 PF13616.6 ORY75051.1 - 5.7e-20 72.0 0.0 8.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ORY75051.1 - 2.1e-18 67.1 0.3 2.9e-18 66.6 0.3 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 ORY75051.1 - 2.6e-05 24.2 0.1 4.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 ORY75051.1 - 0.0028 18.5 0.0 0.0042 17.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 ORY75051.1 - 0.053 14.2 0.0 0.096 13.4 0.0 1.4 1 0 0 1 1 1 0 X8 domain MRG PF05712.13 ORY75052.1 - 2.3e-52 177.2 1.4 3.1e-52 176.8 0.0 1.9 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 ORY75052.1 - 1.1e-07 31.6 0.5 2.6e-07 30.4 0.5 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 ORY75052.1 - 0.0092 15.9 5.3 0.021 14.7 5.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 ORY75052.1 - 0.012 16.0 0.4 0.054 13.9 0.4 2.1 1 0 0 1 1 1 0 PWWP domain MecA PF05389.12 ORY75052.1 - 0.87 9.2 4.3 0.26 10.9 0.5 2.0 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) UPF0172 PF03665.13 ORY75053.1 - 7.2e-52 176.2 0.0 8.7e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 ORY75053.1 - 0.00031 20.7 0.0 0.00042 20.3 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ribosomal_L14 PF00238.19 ORY75054.1 - 5e-35 120.2 0.0 5.7e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e DUF983 PF06170.12 ORY75055.1 - 0.024 15.0 0.5 0.15 12.5 0.5 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF983) NIF PF03031.18 ORY75057.1 - 1e-21 77.3 0.2 1.7e-21 76.6 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 ORY75057.1 - 0.0072 16.1 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family FAM176 PF14851.6 ORY75059.1 - 8.4 6.1 7.3 9.6 5.9 0.5 2.9 3 0 0 3 3 3 0 FAM176 family TPR_2 PF07719.17 ORY75060.1 - 2.1e-11 43.0 1.4 0.00057 19.8 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.24 ORY75060.1 - 5e-11 42.4 0.0 8.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.28 ORY75060.1 - 1.1e-08 34.5 0.1 0.00012 21.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY75060.1 - 1.1e-08 34.6 0.1 3.3e-05 23.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY75060.1 - 2.6e-07 30.8 0.3 0.0002 21.6 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY75060.1 - 0.0019 18.3 0.3 1.5 9.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY75060.1 - 0.0022 18.6 1.7 0.049 14.3 0.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY75060.1 - 0.0075 16.1 1.7 0.3 11.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY75060.1 - 0.014 15.3 0.1 0.13 12.4 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY75060.1 - 0.26 12.2 2.5 6.9 7.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY75060.1 - 2.4 9.0 11.0 13 6.6 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat Methyltransf_16 PF10294.9 ORY75062.1 - 2.4e-14 53.5 0.0 1e-13 51.4 0.0 1.8 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 ORY75062.1 - 0.0096 16.6 0.1 0.64 10.8 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY75062.1 - 0.046 13.1 0.1 0.067 12.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ORY75062.1 - 0.054 13.3 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 ORY75062.1 - 0.062 12.6 0.1 0.095 12.0 0.1 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 ORY75062.1 - 0.19 10.9 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MPC PF03650.13 ORY75063.1 - 5e-34 116.8 0.0 5.8e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Lyase_aromatic PF00221.19 ORY75064.1 - 3.9e-149 497.2 4.8 5.6e-149 496.8 4.8 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase RRM_1 PF00076.22 ORY75065.1 - 0.00054 19.7 0.0 0.00089 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 ORY75065.1 - 0.015 14.7 1.1 0.022 14.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDRGK PF09756.9 ORY75065.1 - 0.094 12.3 7.1 0.13 11.8 7.1 1.1 1 0 0 1 1 1 0 DDRGK domain RNA_polI_A34 PF08208.11 ORY75065.1 - 0.13 12.4 5.2 0.22 11.6 5.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 U79_P34 PF03064.16 ORY75065.1 - 2.7 7.3 7.4 4.1 6.7 7.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Lyase_aromatic PF00221.19 ORY75067.1 - 1.7e-149 498.5 4.1 2.4e-149 497.9 4.1 1.2 1 0 0 1 1 1 1 Aromatic amino acid lyase F-box-like PF12937.7 ORY75290.1 - 0.0062 16.4 0.3 0.023 14.6 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 ORY75290.1 - 0.05 13.4 3.6 0.069 12.9 1.2 2.5 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 ORY75290.1 - 1.5 9.3 5.5 2.8 8.5 0.5 3.5 3 3 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-C2H2 PF00096.26 ORY75291.1 - 1e-08 35.1 1.7 0.0027 18.1 0.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY75291.1 - 1.1e-05 25.8 0.7 0.04 14.8 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger DUF4379 PF14311.6 ORY75291.1 - 0.11 12.9 0.2 0.26 11.7 0.2 1.6 1 0 0 1 1 1 0 Probable Zinc-ribbon domain tRNA-synt_1d PF00750.19 ORY75292.1 - 1e-100 337.1 1.6 1.3e-100 336.7 1.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY75292.1 - 1.5e-18 67.1 0.0 3.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ORY75292.1 - 0.031 14.9 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain F-box-like PF12937.7 ORY75293.1 - 0.012 15.5 1.5 0.013 15.4 0.1 1.9 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 ORY75294.1 - 0.0013 18.6 0.3 0.0013 18.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY75294.1 - 0.0084 16.5 1.7 26 5.4 0.0 4.4 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) Fasciclin PF02469.22 ORY75296.1 - 0.057 13.6 0.0 0.061 13.6 0.0 1.1 1 0 0 1 1 1 0 Fasciclin domain F-box-like PF12937.7 ORY75297.1 - 0.72 9.8 6.7 1.3 8.9 0.7 2.8 2 0 0 2 2 2 0 F-box-like Hist_deacetyl PF00850.19 ORY75298.1 - 1.7e-85 287.2 0.1 2.1e-85 286.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF21 PF01595.20 ORY75299.1 - 2.3e-28 99.1 0.6 3.7e-28 98.4 0.0 1.6 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORY75299.1 - 0.016 15.6 0.7 0.86 10.1 0.0 3.3 3 0 0 3 3 3 0 CBS domain Peptidase_C1_2 PF03051.15 ORY75300.1 - 2.9e-127 425.1 0.0 3.4e-127 424.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 ORY75300.1 - 0.00024 21.2 0.1 0.26 11.3 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease NADH_dehy_S2_C PF06444.11 ORY75300.1 - 0.14 12.7 2.4 0.27 11.8 2.4 1.5 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus LRR_4 PF12799.7 ORY75301.1 - 1 9.9 6.3 6.3 7.4 1.3 3.6 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) Mak10 PF04112.13 ORY75302.1 - 2.4e-35 121.5 0.0 5.8e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF1996 PF09362.10 ORY75303.1 - 1.6e-79 267.2 0.1 1.6e-79 267.2 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) WSC PF01822.19 ORY75303.1 - 3.8e-32 110.3 50.2 7.2e-12 45.3 8.4 4.1 4 0 0 4 4 4 3 WSC domain NETI PF14044.6 ORY75303.1 - 0.47 10.2 2.6 60 3.5 0.0 3.2 3 0 0 3 3 3 0 NETI protein COX17 PF05051.13 ORY75304.1 - 1.6e-21 76.3 3.9 2.2e-21 75.9 3.9 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Peptidase_C1_2 PF03051.15 ORY75305.1 - 2.6e-142 474.7 0.0 2.9e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 ORY75305.1 - 3.5e-05 24.0 0.1 0.11 12.6 0.0 2.5 3 0 0 3 3 3 2 Papain family cysteine protease DUF4296 PF14129.6 ORY75305.1 - 0.13 12.9 0.1 0.3 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) ADH_N PF08240.12 ORY75306.1 - 2.8e-23 81.9 2.7 4.9e-23 81.1 2.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY75306.1 - 1.8e-22 79.7 0.1 3.5e-22 78.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY75306.1 - 9.2e-06 26.7 0.0 2.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY75306.1 - 1.3e-05 24.8 0.3 2.2e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Ldl_recept_b PF00058.17 ORY75307.1 - 3.7e-05 24.1 0.4 5.4 7.6 0.0 5.2 5 1 0 5 5 5 3 Low-density lipoprotein receptor repeat class B DUF5050 PF16472.5 ORY75307.1 - 0.00012 21.5 0.0 0.031 13.5 0.0 1.7 2 1 1 3 3 3 2 Domain of unknown function (DUF5050) SGL PF08450.12 ORY75307.1 - 0.096 12.2 0.8 1.2 8.6 0.0 2.7 3 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region bZIP_1 PF00170.21 ORY75309.1 - 5.8e-08 32.7 7.2 0.00011 22.3 2.1 2.1 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY75309.1 - 4.2e-06 26.8 15.0 0.0034 17.4 2.8 2.1 2 0 0 2 2 2 2 Basic region leucine zipper DivIC PF04977.15 ORY75309.1 - 0.014 15.1 4.9 0.15 11.8 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator HAP1_N PF04849.13 ORY75309.1 - 0.029 13.6 3.3 0.039 13.1 3.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Mto2_bdg PF12808.7 ORY75309.1 - 0.031 14.6 2.3 0.031 14.6 2.3 1.8 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RapA_C PF12137.8 ORY75309.1 - 0.039 13.0 1.4 0.05 12.6 1.4 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Uso1_p115_C PF04871.13 ORY75309.1 - 0.055 13.8 7.1 0.082 13.3 7.1 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3584 PF12128.8 ORY75309.1 - 0.071 10.6 2.9 0.089 10.3 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HALZ PF02183.18 ORY75309.1 - 0.074 13.3 1.0 0.16 12.2 1.0 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF465 PF04325.13 ORY75309.1 - 0.086 12.9 1.7 0.81 9.8 1.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF465) APG6_N PF17675.1 ORY75309.1 - 0.11 13.0 5.3 0.15 12.6 5.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region TSC22 PF01166.18 ORY75309.1 - 0.11 12.8 2.1 1.2 9.5 0.3 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family JIP_LZII PF16471.5 ORY75309.1 - 0.19 11.9 1.4 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II CCD48 PF15799.5 ORY75309.1 - 0.22 9.8 5.6 0.37 9.0 5.6 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 48 DUF1556 PF07590.11 ORY75309.1 - 0.32 11.3 3.7 0.69 10.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1556) DUF4407 PF14362.6 ORY75309.1 - 0.32 10.3 2.5 0.44 9.9 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arginase PF00491.21 ORY75310.1 - 1.1e-85 287.6 0.0 1.3e-85 287.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 ORY75310.1 - 0.032 14.5 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.18 ORY75311.1 - 8.3e-56 188.1 15.9 7.4e-28 97.2 5.1 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 ORY75311.1 - 0.0026 17.8 12.9 0.0026 17.8 12.9 4.1 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain AA_permease_2 PF13520.6 ORY75312.1 - 3.8e-60 203.9 50.8 4.7e-60 203.6 50.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY75312.1 - 2.6e-17 62.6 46.1 3.7e-17 62.1 46.1 1.2 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.24 ORY75313.1 - 1.1e-102 344.2 23.7 1.3e-102 344.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY75313.1 - 4.8e-30 104.7 29.2 4.8e-30 104.7 29.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S21 PF01165.20 ORY75313.1 - 0.038 13.7 0.5 0.055 13.2 0.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S21 Cyclase PF04199.13 ORY75314.1 - 3e-17 63.2 0.0 5.1e-17 62.4 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase SnoaL_4 PF13577.6 ORY75315.1 - 3.5e-13 49.8 0.0 5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.6 ORY75315.1 - 0.021 15.1 0.0 0.064 13.5 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain Sugarporin_N PF11471.8 ORY75315.1 - 0.22 11.5 0.6 0.36 10.8 0.6 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension adh_short_C2 PF13561.6 ORY75316.1 - 5.4e-45 153.8 1.7 2.2e-44 151.8 1.7 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY75316.1 - 7.9e-33 113.6 5.0 1.5e-32 112.7 5.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY75316.1 - 0.005 16.8 2.3 0.012 15.5 2.3 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY75316.1 - 0.0078 16.1 0.6 0.013 15.4 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_11 PF08241.12 ORY75316.1 - 0.13 12.9 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PhyH PF05721.13 ORY75317.1 - 4.4e-05 23.9 0.0 0.00018 21.8 0.0 1.9 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 ORY75317.1 - 0.0025 18.7 0.0 0.0047 17.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 ORY75317.1 - 0.0041 17.5 0.0 0.0089 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Per1 PF04080.13 ORY75318.1 - 2.3e-69 234.0 0.0 1.7e-66 224.6 0.0 2.1 1 1 0 1 1 1 1 Per1-like family DUF3262 PF11660.8 ORY75318.1 - 1.4 9.4 5.2 1.8 9.0 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) Cupin_8 PF13621.6 ORY75319.1 - 2.3e-13 50.5 0.0 4.6e-13 49.5 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY75319.1 - 1.3e-12 48.1 0.0 2.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 ORY75319.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Zn_clus PF00172.18 ORY75320.1 - 4.8e-06 26.6 14.6 7.8e-06 25.9 14.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DBR1 PF05011.13 ORY75321.1 - 7e-34 117.2 0.0 1.5e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 ORY75321.1 - 8.8e-10 39.4 0.1 1.6e-09 38.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY75321.1 - 0.0018 18.5 0.0 0.0046 17.2 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SGL PF08450.12 ORY75322.1 - 1.9e-23 83.3 0.0 4.4e-23 82.2 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORY75322.1 - 0.0046 17.1 0.0 0.04 14.1 0.0 2.4 3 0 0 3 3 3 1 Arylesterase Str_synth PF03088.16 ORY75322.1 - 0.14 12.3 0.0 2.4 8.3 0.0 2.7 3 0 0 3 3 3 0 Strictosidine synthase SBP_bac_11 PF13531.6 ORY75323.1 - 0.00039 20.2 0.1 0.0017 18.2 0.1 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein BTB PF00651.31 ORY75324.1 - 1.6e-07 31.6 0.0 6.3e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 ORY75324.1 - 0.18 12.0 0.0 0.47 10.7 0.0 1.6 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain RRF PF01765.19 ORY75326.1 - 6.2e-38 130.3 0.3 7.5e-38 130.0 0.3 1.0 1 0 0 1 1 1 1 Ribosome recycling factor MAPEG PF01124.18 ORY75327.1 - 1.7e-15 57.1 1.6 1.9e-15 56.9 1.6 1.2 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.18 ORY75328.1 - 1.7e-15 57.1 0.6 2.2e-15 56.7 0.6 1.2 1 0 0 1 1 1 1 MAPEG family D5_N PF08706.11 ORY75330.1 - 0.083 13.2 0.4 0.089 13.1 0.4 1.0 1 0 0 1 1 1 0 D5 N terminal like SnoaL PF07366.12 ORY75331.1 - 8.5e-13 48.2 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORY75331.1 - 6.5e-10 39.6 0.0 7.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain HOCHOB PF17943.1 ORY75332.1 - 0.14 12.8 0.0 0.39 11.4 0.0 1.6 2 0 0 2 2 2 0 Homeobox-cysteine loop-homeobox SnoaL PF07366.12 ORY75333.1 - 7.1e-13 48.5 0.0 8.6e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORY75333.1 - 6.6e-10 39.5 0.0 7.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain ABC_tran PF00005.27 ORY75334.1 - 1.3e-42 145.6 0.0 1.2e-21 77.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY75334.1 - 3.9e-18 66.3 0.4 6.8e-07 29.4 0.1 3.7 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY75334.1 - 2.5e-14 53.3 0.4 0.00017 21.1 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY75334.1 - 1.4e-08 34.3 0.3 0.0052 16.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain 4HB PF17947.1 ORY75334.1 - 3.6e-07 30.2 0.0 1.7e-06 28.0 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain DUF87 PF01935.17 ORY75334.1 - 9.8e-06 25.8 0.0 0.0018 18.4 0.0 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 ORY75334.1 - 1.1e-05 25.8 0.0 0.58 10.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 ORY75334.1 - 2e-05 25.1 0.1 0.036 14.6 0.1 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORY75334.1 - 2.1e-05 24.6 0.3 0.48 10.5 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY75334.1 - 2.8e-05 24.0 0.5 0.059 13.1 0.0 3.0 2 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY75334.1 - 3.5e-05 23.8 0.1 0.065 13.1 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY75334.1 - 7.4e-05 23.3 8.5 0.0093 16.5 0.0 2.9 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 ORY75334.1 - 0.00014 22.3 0.3 0.083 13.3 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ORY75334.1 - 0.00055 19.9 0.0 0.43 10.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 ORY75334.1 - 0.00056 19.7 0.2 2 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain Chromo PF00385.24 ORY75334.1 - 0.00059 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_33 PF13671.6 ORY75334.1 - 0.0007 19.8 0.0 0.56 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ORY75334.1 - 0.0016 18.6 0.1 0.084 13.1 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ORY75334.1 - 0.0017 18.6 0.0 0.55 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY75334.1 - 0.002 18.5 0.1 2 8.8 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY75334.1 - 0.0026 18.1 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase MeaB PF03308.16 ORY75334.1 - 0.0027 16.8 0.2 0.51 9.3 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 ORY75334.1 - 0.0035 17.3 0.1 5 7.0 0.0 3.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 ORY75334.1 - 0.0056 15.4 0.0 1.7 7.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain CLASP_N PF12348.8 ORY75334.1 - 0.0072 15.9 0.2 3.3 7.2 0.0 2.4 1 1 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.6 ORY75334.1 - 0.0089 16.4 4.2 0.012 16.0 0.1 3.1 4 0 0 4 4 2 1 HEAT repeats U3snoRNP10 PF12397.8 ORY75334.1 - 0.0097 16.2 2.0 0.57 10.6 0.8 2.6 1 1 1 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 ORY75334.1 - 0.011 16.2 4.4 12 6.6 0.0 5.2 4 2 1 5 5 4 0 HEAT-like repeat G-alpha PF00503.20 ORY75334.1 - 0.015 14.5 0.0 3.3 6.8 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 ORY75334.1 - 0.016 14.4 0.0 3.5 6.7 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain Dopey_N PF04118.14 ORY75334.1 - 0.021 14.0 0.1 0.073 12.2 0.0 1.8 1 1 0 1 1 1 0 Dopey, N-terminal Dynamin_N PF00350.23 ORY75334.1 - 0.027 14.5 0.1 0.42 10.6 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 ORY75334.1 - 0.028 14.1 0.0 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 ORY75334.1 - 0.034 13.9 0.1 10 5.9 0.1 3.1 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Adaptin_N PF01602.20 ORY75334.1 - 0.044 12.3 3.1 0.11 11.0 1.3 2.1 1 1 0 2 2 2 0 Adaptin N terminal region ATP_bind_1 PF03029.17 ORY75334.1 - 0.055 13.3 0.5 2.9 7.6 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 ORY75334.1 - 0.061 13.3 0.2 14 5.7 0.0 3.2 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 ORY75334.1 - 0.082 12.7 0.0 14 5.4 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 ORY75334.1 - 0.09 11.9 0.3 7 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY75334.1 - 0.095 12.2 0.1 8.2 5.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORY75334.1 - 0.1 11.9 0.9 9 5.6 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family DUF3385 PF11865.8 ORY75334.1 - 0.1 12.5 0.1 7.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) NTPase_1 PF03266.15 ORY75334.1 - 0.13 12.2 0.6 11 5.9 0.1 3.0 3 0 0 3 3 2 0 NTPase Roc PF08477.13 ORY75334.1 - 0.13 12.5 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORY75334.1 - 0.14 11.7 0.3 12 5.4 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 ORY75334.1 - 0.17 11.4 0.9 18 4.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 ORY75334.1 - 0.56 10.2 2.3 15 5.6 0.1 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) HEAT PF02985.22 ORY75334.1 - 4.5 7.8 9.4 94 3.7 0.1 5.0 7 0 0 7 7 3 0 HEAT repeat Pyridoxal_deC PF00282.19 ORY75336.1 - 7.3e-83 278.3 0.0 2.3e-82 276.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Exostosin PF03016.15 ORY75337.1 - 6.5e-32 110.9 0.0 7.7e-16 58.2 0.1 2.1 2 0 0 2 2 2 2 Exostosin family Ribosomal_S6 PF01250.17 ORY75338.1 - 4.6e-25 87.7 0.0 6e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Fungal_trans PF04082.18 ORY75339.1 - 1.1e-11 44.3 0.0 1.8e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY75339.1 - 1.1e-05 25.4 10.7 2.6e-05 24.3 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY75340.1 - 2e-24 86.2 45.8 2e-24 86.2 45.8 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY75340.1 - 0.0062 15.4 21.8 0.096 11.5 8.7 3.1 2 1 1 3 3 3 3 MFS_1 like family FAM217 PF15344.6 ORY75342.1 - 1.1 9.2 8.2 1.9 8.4 8.2 1.3 1 0 0 1 1 1 0 FAM217 family Glycos_transf_1 PF00534.20 ORY75344.1 - 8.3e-27 93.8 0.0 1.3e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY75344.1 - 5.8e-14 52.7 0.0 1e-13 51.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY75344.1 - 2.9e-13 50.2 1.6 5.7e-12 46.0 1.3 2.4 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ORY75344.1 - 1.4e-07 31.8 0.0 3.3e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY75344.1 - 4.9e-07 30.3 3.8 1.4e-06 28.8 3.8 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 ORY75344.1 - 0.069 13.2 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 ALG11 mannosyltransferase N-terminus RIBIOP_C PF04950.12 ORY75345.1 - 1.3e-112 376.0 0.0 2.2e-112 375.3 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY75345.1 - 8.1e-21 73.9 0.0 2.2e-20 72.5 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SpoIIIAH PF12685.7 ORY75345.1 - 2.1 8.1 9.4 0.58 9.9 1.0 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Pkinase PF00069.25 ORY75346.1 - 1.7e-42 145.6 0.0 2.7e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY75346.1 - 1.5e-21 76.9 0.0 2e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ORY75346.1 - 0.002 17.2 0.1 0.0032 16.5 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 ORY75346.1 - 0.0023 17.6 0.2 0.044 13.4 0.2 2.3 1 1 0 1 1 1 1 RIO1 family Calcipressin PF04847.12 ORY75349.1 - 1e-26 93.8 0.0 2.7e-26 92.5 0.0 1.7 1 1 0 1 1 1 1 Calcipressin SnoaL PF07366.12 ORY75353.1 - 3.1e-16 59.3 0.0 3.7e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORY75353.1 - 2.2e-11 44.3 0.0 2.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain zf-C2H2 PF00096.26 ORY75354.1 - 2.6e-06 27.6 9.2 0.00031 21.0 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY75354.1 - 0.00021 21.6 3.1 0.00096 19.5 3.1 2.3 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY75354.1 - 0.035 14.9 13.2 0.32 11.9 1.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger RRS1 PF04939.12 ORY75354.1 - 0.45 10.4 8.2 0.84 9.5 8.2 1.4 1 0 0 1 1 1 0 Ribosome biogenesis regulatory protein (RRS1) CDC45 PF02724.14 ORY75354.1 - 0.73 8.1 5.8 1.2 7.4 5.8 1.3 1 0 0 1 1 1 0 CDC45-like protein VRR_NUC PF08774.11 ORY75355.1 - 8.6e-23 80.5 0.0 1.9e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain DUF4604 PF15377.6 ORY75355.1 - 1.3 9.4 10.0 6.3 7.2 1.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Cellulase PF00150.18 ORY75356.1 - 1.3e-09 37.9 1.3 2e-09 37.3 0.0 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) BTB PF00651.31 ORY75358.1 - 3.5e-19 69.1 0.0 4.4e-08 33.3 0.0 3.3 2 1 1 3 3 3 2 BTB/POZ domain RCC1 PF00415.18 ORY75358.1 - 3.2e-15 56.5 0.6 0.00028 21.5 0.0 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 ORY75358.1 - 2.4e-07 31.2 0.2 0.00011 22.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.6 ORY75358.1 - 3.1e-07 30.0 3.3 0.00025 20.7 0.0 4.6 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 ORY75358.1 - 7.3e-06 26.2 0.6 0.0075 16.6 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY75358.1 - 2.7e-05 24.7 0.0 5.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY75358.1 - 0.0056 17.1 0.1 2.9 8.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORY75358.1 - 0.072 13.7 0.2 2.6 8.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat PAM2 PF07145.15 ORY75358.1 - 0.099 12.4 1.6 3.2 7.6 0.6 2.7 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RTA1 PF04479.13 ORY75359.1 - 1.3e-38 132.7 13.2 1.3e-38 132.7 13.2 1.6 2 0 0 2 2 2 1 RTA1 like protein Pex2_Pex12 PF04757.14 ORY75360.1 - 4.8e-42 144.1 5.8 6e-42 143.8 5.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 ORY75360.1 - 0.29 11.0 2.4 0.45 10.4 2.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ox_reductase_C PF08635.10 ORY75361.1 - 2.1e-70 234.9 0.2 3e-70 234.4 0.2 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal domain GFO_IDH_MocA PF01408.22 ORY75361.1 - 8.9e-21 74.9 0.0 1.6e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY75361.1 - 0.0041 17.1 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Chlor_dismutase PF06778.12 ORY75361.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorite dismutase BTB_2 PF02214.22 ORY75364.1 - 0.099 13.0 0.0 0.77 10.1 0.0 2.4 1 1 1 2 2 2 0 BTB/POZ domain RF-1 PF00472.20 ORY75366.1 - 5.1e-21 74.8 1.2 8.3e-21 74.1 1.2 1.4 1 0 0 1 1 1 1 RF-1 domain MAP17 PF15807.5 ORY75366.1 - 3.6 7.9 7.4 0.36 11.1 2.6 1.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Gtr1_RagA PF04670.12 ORY75370.1 - 1.7e-74 250.1 0.1 5.6e-41 140.4 0.0 2.0 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY75370.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY75370.1 - 6.5e-05 23.0 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 ORY75370.1 - 0.0002 20.8 0.0 0.00053 19.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 ORY75370.1 - 0.00033 20.3 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 ORY75370.1 - 0.013 15.4 0.1 2.6 7.9 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 ORY75370.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ORY75370.1 - 0.029 14.9 0.2 0.1 13.1 0.2 1.8 2 1 0 2 2 2 0 ABC transporter PduV-EutP PF10662.9 ORY75370.1 - 0.039 13.7 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 ORY75370.1 - 0.061 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 ORY75370.1 - 0.15 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Aldo_ket_red PF00248.21 ORY75371.1 - 5.8e-42 143.9 0.1 2.2e-40 138.7 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_6 PF12697.7 ORY75372.1 - 5.2e-06 27.2 2.1 7.1e-06 26.8 2.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY75372.1 - 0.0047 16.6 0.7 0.0089 15.7 0.7 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 ORY75372.1 - 0.02 14.7 0.1 0.027 14.3 0.1 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 ORY75372.1 - 0.061 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ORY75372.1 - 0.087 12.1 0.2 0.28 10.4 0.1 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF915 PF06028.11 ORY75372.1 - 0.26 10.6 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ERG2_Sigma1R PF04622.12 ORY75373.1 - 6.5e-87 290.3 0.4 7.8e-87 290.0 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein LacY_symp PF01306.19 ORY75375.1 - 0.046 12.5 0.8 0.051 12.4 0.8 1.0 1 0 0 1 1 1 0 LacY proton/sugar symporter MHC2-interact PF09307.10 ORY75375.1 - 0.05 13.6 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting DUF2273 PF10031.9 ORY75375.1 - 1.9 8.6 5.1 0.57 10.2 0.4 2.0 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) YL1 PF05764.13 ORY75377.1 - 2.9e-45 155.3 22.1 5.1e-45 154.5 22.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein BSP_II PF05432.11 ORY75377.1 - 0.033 13.9 11.4 0.065 12.9 11.4 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 ORY75377.1 - 1.1 7.3 13.8 1.8 6.6 13.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 ORY75377.1 - 2.2 7.2 8.2 3.1 6.8 8.2 1.2 1 0 0 1 1 1 0 Pes-10 Nt_Gln_amidase PF09764.9 ORY75379.1 - 3.1e-36 124.7 0.0 4.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal glutamine amidase Gln_deamidase_2 PF18626.1 ORY75379.1 - 0.13 12.5 0.1 0.19 12.0 0.1 1.2 1 0 0 1 1 1 0 Glutaminase HECT PF00632.25 ORY75381.1 - 2.9e-93 312.7 0.0 3.9e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORY75381.1 - 1.4e-21 76.3 9.6 6.8e-11 42.1 4.0 2.5 2 0 0 2 2 2 2 WW domain C2 PF00168.30 ORY75381.1 - 4.3e-09 36.6 0.0 8.3e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain BTB_2 PF02214.22 ORY75382.1 - 0.00032 21.0 0.1 0.0015 18.9 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain zf-H2C2_2 PF13465.6 ORY75383.1 - 4.8e-24 83.7 38.3 3.8e-08 33.4 0.6 5.9 7 0 0 7 7 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORY75383.1 - 1.3e-18 66.3 48.6 1.1e-05 25.6 0.2 7.2 8 0 0 8 8 6 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY75383.1 - 1.6e-10 40.9 52.2 0.00038 21.1 0.4 7.3 8 0 0 8 8 6 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY75383.1 - 1.2e-08 35.0 9.3 0.00055 20.1 0.1 5.7 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY75383.1 - 1.8e-05 24.6 20.4 0.0055 16.7 0.4 5.4 5 0 0 5 5 5 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORY75383.1 - 0.00034 21.2 7.0 0.003 18.2 1.9 7.0 4 2 4 8 8 7 2 FOXP coiled-coil domain zf_UBZ PF18439.1 ORY75383.1 - 0.0006 19.4 8.0 0.12 12.0 0.1 3.3 4 0 0 4 4 4 2 Ubiquitin-Binding Zinc Finger zf_ZIC PF18366.1 ORY75383.1 - 0.00064 19.8 0.3 0.00064 19.8 0.3 4.3 4 1 1 5 5 5 1 Zic proteins zinc finger domain zf-met PF12874.7 ORY75383.1 - 0.0025 18.1 9.0 0.018 15.5 0.5 4.3 4 0 0 4 4 3 1 Zinc-finger of C2H2 type zf-MYST PF17772.1 ORY75383.1 - 0.0056 16.3 0.4 3.1 7.5 0.1 2.7 2 1 0 2 2 2 2 MYST family zinc finger domain zf-C2H2_aberr PF17017.5 ORY75383.1 - 0.0065 16.6 5.4 0.12 12.5 1.3 3.4 2 2 1 3 3 3 1 Aberrant zinc-finger DUF629 PF04780.12 ORY75383.1 - 0.0072 14.9 10.1 1.1 7.7 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.6 ORY75383.1 - 0.015 15.2 0.6 12 5.9 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type IBR PF01485.21 ORY75383.1 - 0.043 14.1 1.6 0.043 14.1 1.6 3.4 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 ORY75383.1 - 0.13 12.1 4.4 8.4 6.3 0.1 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 ORY75383.1 - 0.21 11.3 6.6 1.8 8.3 0.1 3.7 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain PyrI_C PF02748.15 ORY75383.1 - 0.67 9.9 8.9 3 7.8 0.4 3.3 2 1 1 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Ogr_Delta PF04606.12 ORY75383.1 - 1.5 8.9 6.2 1.4 9.0 2.1 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger XPA_N PF01286.18 ORY75383.1 - 1.8 8.6 6.7 1.5 8.9 0.3 2.9 3 0 0 3 3 2 0 XPA protein N-terminal Zn-ribbon_8 PF09723.10 ORY75383.1 - 2.6 8.2 7.3 3.1 8.0 0.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain zinc_ribbon_15 PF17032.5 ORY75383.1 - 3.9 8.3 10.7 0.59 10.9 0.8 2.9 2 1 1 3 3 3 0 zinc-ribbon family BTB_2 PF02214.22 ORY75384.1 - 0.0011 19.3 0.0 0.0027 18.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 ORY75385.1 - 1.7e-07 31.4 0.0 3e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 ORY75385.1 - 0.004 17.3 0.0 0.0091 16.1 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Alpha-E PF04168.12 ORY75385.1 - 0.012 15.4 0.2 0.015 15.1 0.2 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. SnoaL PF07366.12 ORY75386.1 - 4.7e-18 65.2 0.0 5.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORY75386.1 - 6.8e-13 49.1 0.0 8.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain LRR_2 PF07723.13 ORY75388.1 - 0.079 13.7 0.0 6.2 7.7 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat NAD_binding_10 PF13460.6 ORY75389.1 - 1.8e-15 57.3 0.0 2.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY75389.1 - 1.7e-14 54.0 0.0 2.1e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY75389.1 - 9.2e-14 51.5 0.1 2.5e-12 46.8 0.1 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY75389.1 - 3.1e-10 39.6 0.0 5.2e-08 32.3 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY75389.1 - 1.3e-08 34.2 0.0 3.5e-08 32.8 0.0 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY75389.1 - 9.6e-07 28.2 0.1 0.0022 17.2 0.0 2.7 1 1 2 3 3 3 2 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY75389.1 - 6.3e-06 25.8 0.0 6.6e-05 22.5 0.0 2.2 2 1 1 3 3 3 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY75389.1 - 0.00086 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY75389.1 - 0.03 13.9 0.0 0.068 12.7 0.0 1.5 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY75389.1 - 0.065 13.1 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 KR domain GRIP PF01465.20 ORY75390.1 - 2.4e-14 53.0 0.0 5.5e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 GRIP domain DUF4806 PF16064.5 ORY75390.1 - 7.7 6.9 6.0 39 4.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) CK2S PF15011.6 ORY75391.1 - 0.0019 18.1 0.1 0.0046 16.9 0.1 1.7 1 1 0 1 1 1 1 Casein Kinase 2 substrate AIM5 PF17050.5 ORY75391.1 - 0.024 15.4 7.5 7.9 7.4 0.0 3.5 3 0 0 3 3 3 0 Altered inheritance of mitochondria 5 DUF3446 PF11928.8 ORY75391.1 - 6.6 7.1 9.9 22 5.4 0.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain ABC_tran PF00005.27 ORY75617.1 - 1.8e-25 90.0 0.0 5.3e-17 62.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY75617.1 - 6.6e-06 26.1 0.4 0.14 11.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY75617.1 - 3.7e-05 23.3 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY75617.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY75617.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 ORY75617.1 - 0.057 13.7 0.0 0.96 9.7 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ORY75617.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY75617.1 - 0.095 13.2 1.3 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Glyco_transf_49 PF13896.6 ORY75618.1 - 7.9e-67 225.9 0.8 6.2e-53 180.3 0.1 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan G-alpha PF00503.20 ORY75620.1 - 1.7e-113 379.4 0.0 2e-113 379.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY75620.1 - 5.1e-16 58.6 0.2 5e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY75620.1 - 2.5e-05 23.8 0.4 0.17 11.2 0.2 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY75620.1 - 0.0026 18.0 0.2 0.92 9.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 ORY75620.1 - 0.076 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain LSM PF01423.22 ORY75621.1 - 3.3e-17 61.9 0.0 5e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 LSM domain Feld-I_B PF09252.10 ORY75621.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain T4SS_CagC PF16943.5 ORY75622.1 - 0.033 14.4 1.4 0.15 12.2 0.8 2.4 2 1 1 3 3 3 0 Cag pathogenicity island, type IV secretory system Glyoxalase PF00903.25 ORY75625.1 - 5.5e-14 52.5 0.0 3.1e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY75625.1 - 5.2e-10 39.6 0.0 3.2e-09 37.0 0.0 1.6 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORY75625.1 - 0.0012 19.7 0.0 0.0096 16.7 0.0 2.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ORY75625.1 - 0.064 13.4 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain DUF1421 PF07223.11 ORY75625.1 - 0.16 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain (DUF1421) Chalcone_2 PF16035.5 ORY75626.1 - 1.4e-37 129.5 0.0 2e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 ORY75626.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 ORY75626.1 - 0.026 13.9 0.2 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 Chalcone-flavanone isomerase ApbA PF02558.16 ORY75627.1 - 2.4e-21 76.0 0.0 3.9e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ORY75627.1 - 5.4e-20 71.9 0.0 4.4e-19 68.9 0.0 2.4 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 ORY75627.1 - 0.12 12.6 0.1 0.3 11.4 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3337 PF11816.8 ORY75629.1 - 1.7e-42 145.2 0.0 2.7e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 ORY75629.1 - 2e-18 66.4 18.9 2.7e-05 24.9 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY75629.1 - 0.00031 21.0 0.1 0.033 14.5 0.1 2.9 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 ORY75629.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) NYD-SP28_assoc PF14775.6 ORY75630.1 - 0.029 14.4 0.4 0.087 12.9 0.4 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain Baculo_RING PF05883.11 ORY75630.1 - 0.29 11.1 1.3 0.6 10.1 1.3 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain MFS_1 PF07690.16 ORY75631.1 - 1.7e-21 76.5 15.7 3.2e-21 75.7 15.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY75631.1 - 1e-07 31.7 8.9 4.3e-07 29.7 8.9 2.1 1 1 0 1 1 1 1 Nodulin-like DUF2523 PF10734.9 ORY75631.1 - 0.078 13.6 0.7 0.078 13.6 0.7 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2523) Peptidase_S10 PF00450.22 ORY75632.1 - 5.3e-96 322.6 0.0 6.9e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Cellulase PF00150.18 ORY75633.1 - 1e-15 58.0 0.0 1.3e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA-synt_1 PF00133.22 ORY75634.1 - 3.1e-208 692.9 0.2 5.5e-207 688.7 0.0 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY75634.1 - 8.6e-37 126.4 0.1 1.9e-36 125.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY75634.1 - 7.4e-14 51.3 0.0 2.4e-06 26.6 0.0 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORY75634.1 - 2.9e-09 36.7 0.4 8e-06 25.5 0.0 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 ORY75634.1 - 0.0014 18.9 4.6 0.0014 18.9 4.6 2.4 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 ORY75634.1 - 0.0094 15.3 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain TFIIE-A_C PF11521.8 ORY75635.1 - 0.025 14.9 4.3 0.049 13.9 0.6 2.2 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha TIP41 PF04176.13 ORY75636.1 - 3.7e-55 186.0 0.0 4.6e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family WD40 PF00400.32 ORY75637.1 - 2e-24 85.4 12.8 0.00023 21.9 0.2 7.0 5 1 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY75637.1 - 3.5e-10 40.0 0.1 0.095 13.0 0.0 4.4 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY75637.1 - 0.00025 20.1 0.0 0.8 8.6 0.0 3.3 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VCBS PF13517.6 ORY75637.1 - 0.0069 16.9 1.3 20 5.8 0.0 4.4 3 1 2 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CDH-cyt PF16010.5 ORY75638.1 - 3.1e-08 33.5 5.1 1.9e-07 31.0 3.3 2.1 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 ORY75638.1 - 2.5e-07 30.9 0.1 3.3e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 ORY75639.1 - 1.3e-05 25.3 10.9 0.00011 22.4 10.5 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Serglycin PF04360.12 ORY75639.1 - 0.026 14.5 7.4 0.026 14.5 7.4 4.1 2 1 0 2 2 2 0 Serglycin PTPRCAP PF15713.5 ORY75639.1 - 0.78 10.0 20.8 1 9.7 4.5 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF2427 PF10348.9 ORY75639.1 - 1.1 9.1 8.0 0.11 12.3 3.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) tRNA-synt_1b PF00579.25 ORY75640.1 - 2e-60 204.6 0.1 1.1e-59 202.2 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) FA_hydroxylase PF04116.13 ORY75641.1 - 1.6e-23 83.5 15.8 1.6e-23 83.5 15.8 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NUDIX_2 PF13869.6 ORY75642.1 - 7.8e-76 253.9 0.0 9.2e-76 253.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase Atg14 PF10186.9 ORY75643.1 - 0.022 13.8 6.3 0.028 13.5 6.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Calpain_inhib PF00748.19 ORY75643.1 - 0.45 11.0 10.2 0.97 9.9 10.2 1.5 1 0 0 1 1 1 0 Calpain inhibitor DUF3584 PF12128.8 ORY75643.1 - 0.55 7.7 10.8 0.74 7.2 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Acyl_transf_1 PF00698.21 ORY75644.1 - 9.1e-21 74.7 2.4 1.5e-12 47.7 1.8 3.0 2 1 0 2 2 2 2 Acyl transferase domain SAT PF16073.5 ORY75644.1 - 6.1e-07 29.4 0.5 1e-06 28.7 0.5 1.3 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Nucleo_P87 PF07267.11 ORY75645.1 - 0.31 9.8 4.3 0.52 9.1 4.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.12 ORY75645.1 - 0.34 10.6 6.9 0.54 9.9 6.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CSL PF05207.13 ORY75646.1 - 5.5e-23 80.4 0.5 6.9e-23 80.1 0.5 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 ORY75646.1 - 0.00081 19.5 0.5 0.0012 19.0 0.5 1.3 1 0 0 1 1 1 1 Zinc ribbon domain zinc_ribbon_4 PF13717.6 ORY75646.1 - 0.025 14.5 0.7 0.041 13.8 0.7 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_7 PF02591.15 ORY75646.1 - 0.044 14.0 0.0 0.087 13.0 0.0 1.5 1 0 0 1 1 1 0 C4-type zinc ribbon domain Metallothio_PEC PF02068.16 ORY75646.1 - 0.053 13.9 0.3 0.077 13.4 0.3 1.2 1 0 0 1 1 1 0 Plant PEC family metallothionein GAGA PF09237.11 ORY75646.1 - 0.15 11.9 0.3 0.22 11.3 0.3 1.3 1 1 0 1 1 1 0 GAGA factor Sulfate_transp PF00916.20 ORY75647.1 - 9.3e-57 192.5 20.7 1.4e-56 191.9 20.7 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 ORY75647.1 - 9.1e-16 57.7 0.0 1.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 ORY75647.1 - 4e-10 39.3 0.1 1.4e-08 34.4 0.0 2.4 1 1 1 2 2 2 1 STAS domain Arrestin_N PF00339.29 ORY75649.1 - 0.00048 20.2 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORY75649.1 - 0.0034 16.6 0.1 0.0055 15.9 0.1 1.2 1 0 0 1 1 1 1 Rgp1 RabGAP-TBC PF00566.18 ORY75652.1 - 1.6e-48 165.2 0.0 2.4e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.6 ORY75652.1 - 4.7e-07 30.2 0.1 0.00022 21.6 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair GRAM PF02893.20 ORY75652.1 - 7.2e-07 29.1 0.0 1.4e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 ORY75652.1 - 0.00014 21.5 0.2 0.0044 16.8 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 ORY75652.1 - 0.00019 20.7 0.0 0.012 15.1 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 ORY75652.1 - 0.0074 16.1 0.0 0.049 13.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair GATA PF00320.27 ORY75653.1 - 1.8e-11 43.5 2.1 3.1e-11 42.7 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger DHBP_synthase PF00926.19 ORY75654.1 - 2.8e-85 284.7 0.0 3.2e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase FliJ PF02050.16 ORY75655.1 - 0.008 16.4 4.0 0.008 16.4 4.0 3.3 1 1 2 3 3 3 1 Flagellar FliJ protein TPR_MLP1_2 PF07926.12 ORY75655.1 - 0.055 13.5 29.6 0.57 10.2 13.9 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 ORY75655.1 - 0.19 11.0 26.4 0.051 12.9 10.8 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Myc_N PF01056.18 ORY75655.1 - 0.25 11.2 8.7 0.04 13.8 4.5 1.8 1 1 0 1 1 1 0 Myc amino-terminal region EzrA PF06160.12 ORY75655.1 - 0.28 9.3 18.6 0.048 11.8 13.2 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 ORY75655.1 - 0.33 11.0 5.7 0.2 11.7 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 ORY75655.1 - 0.52 10.6 18.6 0.27 11.5 6.0 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein Fez1 PF06818.15 ORY75655.1 - 0.57 10.6 24.8 1.5 9.3 23.7 2.1 1 1 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 ORY75655.1 - 0.57 8.0 13.6 3.8 5.3 13.6 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.11 ORY75655.1 - 0.9 10.0 6.2 27 5.3 0.1 3.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 ORY75655.1 - 1 10.0 18.3 4.6 7.9 0.3 4.3 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 YlqD PF11068.8 ORY75655.1 - 1.1 9.6 16.1 1.2 9.5 11.6 2.7 1 1 2 3 3 3 0 YlqD protein DUF724 PF05266.14 ORY75655.1 - 1.1 9.0 20.3 2.1 8.1 8.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF3509 PF12021.8 ORY75655.1 - 1.1 9.0 5.9 1.8 8.4 0.7 3.2 2 1 1 4 4 3 0 Protein of unknown function (DUF3509) Lebercilin PF15619.6 ORY75655.1 - 1.2 8.8 29.3 1.7 8.2 11.0 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease COG5 PF10392.9 ORY75655.1 - 1.3 9.2 10.3 10 6.3 3.1 2.9 1 1 1 3 3 3 0 Golgi transport complex subunit 5 Fib_alpha PF08702.10 ORY75655.1 - 1.4 9.1 13.3 4 7.6 1.9 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF745 PF05335.13 ORY75655.1 - 1.4 8.6 15.7 2.4 7.8 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) KASH_CCD PF14662.6 ORY75655.1 - 2.9 7.7 24.9 0.19 11.5 9.6 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Leu_zip PF15294.6 ORY75655.1 - 3.5 7.1 19.5 2.4 7.6 9.6 2.3 1 1 1 2 2 2 0 Leucine zipper Macoilin PF09726.9 ORY75655.1 - 3.6 6.0 20.5 6.8 5.1 19.9 1.7 1 1 0 1 1 1 0 Macoilin family SpecificRecomb PF10136.9 ORY75655.1 - 7.8 4.7 6.6 9.8 4.3 6.6 1.2 1 0 0 1 1 1 0 Site-specific recombinase CorA PF01544.18 ORY75655.1 - 8.7 5.6 14.5 3.1 7.0 10.9 2.1 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Ribosomal_L23 PF00276.20 ORY75656.1 - 5.5e-09 36.3 0.0 1.5e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 Zn_clus PF00172.18 ORY75657.1 - 1.3e-06 28.4 9.6 2.7e-06 27.4 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 ORY75658.1 - 3.9e-14 52.5 6.8 3.9e-13 49.3 0.3 2.5 2 0 0 2 2 2 2 DnaJ domain Ank_2 PF12796.7 ORY75658.1 - 1.5e-13 51.1 0.0 1.3e-06 28.8 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY75658.1 - 2.8e-07 31.0 0.3 2e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY75658.1 - 2.5e-06 27.4 0.0 0.0096 16.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY75658.1 - 1.8e-05 24.9 0.0 0.00039 20.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY75658.1 - 0.0012 19.2 0.0 0.13 12.7 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat CPSase_L_D2 PF02786.17 ORY75659.1 - 8.6e-107 355.4 0.3 8.4e-83 277.0 0.0 2.7 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ORY75659.1 - 1.1e-40 138.8 0.1 2.6e-40 137.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 ORY75659.1 - 2e-17 63.3 0.0 3.8e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORY75659.1 - 5.8e-12 45.5 0.0 1.6e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 ORY75659.1 - 1.4e-11 44.4 0.2 5.2e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.11 ORY75659.1 - 4.9e-08 32.8 0.0 0.0031 17.1 0.0 3.3 2 1 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 ORY75659.1 - 3.3e-06 26.7 0.1 0.007 15.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_M17_N PF02789.17 ORY75659.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain MGS PF02142.22 ORY75659.1 - 0.16 12.2 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 MGS-like domain Peptidase_M19 PF01244.21 ORY75660.1 - 4.2e-97 325.1 0.0 1.3e-65 221.6 0.0 2.0 2 0 0 2 2 2 2 Membrane dipeptidase (Peptidase family M19) GIDA PF01134.22 ORY75661.1 - 8.2e-152 505.8 0.0 1e-151 505.5 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 ORY75661.1 - 1.6e-67 227.8 0.0 2.3e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 ORY75661.1 - 1.2e-07 31.2 0.1 7.2e-07 28.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY75661.1 - 4e-05 23.1 4.6 5.9e-05 22.6 3.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY75661.1 - 0.00058 19.0 3.2 0.001 18.3 3.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY75661.1 - 0.00094 18.0 3.5 0.32 9.6 1.4 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.27 ORY75661.1 - 0.0058 17.2 0.1 0.015 15.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY75661.1 - 0.01 15.1 0.0 0.44 9.7 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY75661.1 - 0.011 15.9 1.3 0.028 14.7 1.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORY75661.1 - 0.014 14.7 0.2 0.024 13.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORY75661.1 - 0.11 12.1 3.8 2.3 7.7 1.9 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase ABC2_membrane PF01061.24 ORY75662.1 - 6.2e-36 123.8 22.8 6.2e-36 123.8 22.8 2.3 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 ORY75662.1 - 2.4e-24 86.4 0.0 3.8e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY75662.1 - 0.00051 20.0 0.1 0.001 19.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORY75662.1 - 0.0013 18.4 0.1 0.003 17.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY75662.1 - 0.0031 17.4 0.1 2.6 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY75662.1 - 0.0031 17.9 0.0 0.0061 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY75662.1 - 0.034 14.4 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY75662.1 - 0.063 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY75662.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY75662.1 - 0.14 12.6 0.1 0.23 11.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ORY75662.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase NACHT PF05729.12 ORY75662.1 - 0.16 11.9 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 ORY75662.1 - 0.16 12.0 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 ORY75662.1 - 0.3 11.2 0.3 0.48 10.5 0.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 ORY75662.1 - 0.87 8.6 36.7 6.5 5.8 35.5 2.8 2 1 1 3 3 3 0 ABC-2 family transporter protein CFEM PF05730.11 ORY75663.1 - 1.3e-10 41.2 11.4 2.4e-10 40.4 11.4 1.4 1 0 0 1 1 1 1 CFEM domain TMEM72 PF16054.5 ORY75663.1 - 0.44 10.2 3.1 0.68 9.6 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein family 72 DSBA PF01323.20 ORY75665.1 - 3.1e-29 102.1 0.0 3.5e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY75665.1 - 0.0062 16.7 0.0 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 ORY75665.1 - 0.026 14.6 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain SNF5 PF04855.12 ORY75668.1 - 2.7e-68 230.3 0.2 3.9e-68 229.8 0.2 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 ORY75668.1 - 0.00022 20.7 1.1 0.00045 19.8 1.1 1.5 1 0 0 1 1 1 1 GATA zinc finger Elf1 PF05129.13 ORY75668.1 - 0.19 11.8 0.1 3.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TrkH PF02386.16 ORY75669.1 - 9.4e-107 357.5 3.4 5.1e-106 355.1 0.7 2.0 2 0 0 2 2 2 2 Cation transport protein TrkH PF02386.16 ORY75670.1 - 1.8e-117 392.9 11.1 5.7e-114 381.3 7.2 2.1 2 0 0 2 2 2 2 Cation transport protein GATA PF00320.27 ORY75671.1 - 5.6e-25 86.6 16.4 7.5e-14 51.0 4.3 2.3 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 ORY75671.1 - 6.6e-05 23.0 3.4 0.042 14.0 0.4 2.3 2 0 0 2 2 2 2 Zinc ribbon domain DZR PF12773.7 ORY75671.1 - 0.0027 17.7 5.5 0.016 15.2 5.5 2.2 1 1 0 1 1 1 1 Double zinc ribbon Auto_anti-p27 PF06677.12 ORY75671.1 - 0.012 15.7 5.0 0.88 9.8 0.8 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_15 PF17032.5 ORY75671.1 - 0.02 15.6 1.3 0.8 10.5 0.3 2.6 1 1 1 2 2 2 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 ORY75671.1 - 0.021 14.3 4.7 2.3 7.8 0.1 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.7 ORY75671.1 - 0.023 14.7 4.7 0.79 9.7 0.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.17 ORY75671.1 - 0.027 14.3 5.5 1.3 9.0 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Elf1 PF05129.13 ORY75671.1 - 0.095 12.8 6.9 0.41 10.7 0.4 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.11 ORY75671.1 - 0.11 12.4 6.4 1.4 8.9 0.3 2.4 2 1 0 2 2 2 0 Putative transposase DNA-binding domain ArfGap PF01412.18 ORY75671.1 - 0.11 12.5 3.1 6.5 6.9 0.7 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf zinc_ribbon_9 PF14369.6 ORY75671.1 - 1.3 9.3 7.4 1.3 9.3 0.4 2.7 3 0 0 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 ORY75671.1 - 3 7.4 9.6 43 3.7 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain SPX PF03105.19 ORY75672.1 - 0.33 10.8 5.0 0.46 10.4 5.0 1.4 1 0 0 1 1 1 0 SPX domain Stc1 PF12898.7 ORY75673.1 - 1.5e-08 35.1 11.9 6.2e-06 26.7 15.1 2.3 1 1 1 2 2 2 2 Stc1 domain RXT2_N PF08595.11 ORY75673.1 - 0.15 12.1 3.9 0.23 11.5 3.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4820 PF16091.5 ORY75673.1 - 0.17 11.2 7.1 0.25 10.7 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PBP1_TM PF14812.6 ORY75673.1 - 1.3 9.5 6.9 4.5 7.7 6.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C4pol PF14260.6 ORY75673.1 - 5.6 7.5 9.7 12 6.4 9.7 1.6 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Aldose_epim PF01263.20 ORY75674.1 - 5.1e-23 81.8 0.0 6.2e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase 14-3-3 PF00244.20 ORY75675.1 - 5.7e-105 349.7 2.6 6.6e-105 349.5 2.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 ORY75675.1 - 0.022 13.2 1.9 0.035 12.5 1.9 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 CENP-S PF15630.6 ORY75676.1 - 7.6e-28 96.7 0.2 1.2e-27 96.1 0.2 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY75676.1 - 5.3e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold DEC-1_N PF04625.13 ORY75676.1 - 0.0061 15.6 1.6 0.0061 15.6 1.6 1.5 1 1 1 2 2 2 1 DEC-1 protein, N-terminal region Corona_NS2A PF05213.12 ORY75676.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NS2A protein Histone PF00125.24 ORY75676.1 - 0.58 10.5 0.0 0.58 10.5 0.0 2.4 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF2868 PF11067.8 ORY75676.1 - 2.3 7.7 7.3 1.8 8.0 5.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2868) PBP1_TM PF14812.6 ORY75677.1 - 0.022 15.1 5.8 2.4 8.6 3.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 ORY75677.1 - 0.026 14.2 3.8 0.053 13.3 3.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4330 PF14221.6 ORY75677.1 - 0.042 14.1 2.0 0.068 13.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) PGA2 PF07543.12 ORY75677.1 - 0.39 10.7 2.2 0.85 9.6 2.2 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 TarH PF02203.15 ORY75677.1 - 1.3 8.9 8.0 0.17 11.8 0.8 2.2 1 1 1 2 2 2 0 Tar ligand binding domain homologue zf-HIT PF04438.16 ORY75679.1 - 3.2 7.7 6.1 4.2 7.3 1.1 2.5 2 0 0 2 2 2 0 HIT zinc finger F-box-like PF12937.7 ORY75683.1 - 1.1e-05 25.2 0.1 5.9e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORY75683.1 - 0.045 13.6 0.4 0.62 10.0 0.4 2.5 1 1 0 1 1 1 0 F-box domain LSM PF01423.22 ORY75685.1 - 1.1e-17 63.4 0.4 1.2e-17 63.3 0.4 1.0 1 0 0 1 1 1 1 LSM domain Amidohydro_1 PF01979.20 ORY75686.1 - 7.4e-08 32.1 0.0 3.5e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 ORY75686.1 - 0.00033 20.6 0.1 0.00053 19.9 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase IBN_N PF03810.19 ORY75687.1 - 2.4e-10 40.2 0.0 7.7e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 ORY75687.1 - 0.0001 22.6 1.6 0.31 11.5 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats Xpo1 PF08389.12 ORY75687.1 - 0.045 13.8 0.5 0.32 11.1 0.0 2.9 3 0 0 3 3 3 0 Exportin 1-like protein DUF717 PF05338.12 ORY75687.1 - 0.082 13.0 0.0 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Fungal_trans PF04082.18 ORY75688.1 - 1.7e-20 73.2 0.0 2.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY75688.1 - 0.00052 20.1 9.2 0.00095 19.2 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkr1 PF08636.10 ORY75689.1 - 5.9e-26 90.4 0.3 6.9e-26 90.2 0.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Ribosomal_S18 PF01084.20 ORY75691.1 - 8.3e-11 41.9 0.1 1.3e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 Polysacc_lyase PF14099.6 ORY75692.1 - 0.0064 16.4 0.0 0.039 13.8 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide lyase Pkinase PF00069.25 ORY75693.1 - 4.7e-50 170.4 0.0 1.8e-40 139.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY75693.1 - 1.1e-21 77.4 0.0 1.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Response_reg PF00072.24 ORY75693.1 - 4.6e-10 39.6 0.0 8.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 ORY75693.1 - 1.9e-05 24.1 0.1 0.00032 20.1 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PAS PF00989.25 ORY75693.1 - 0.00012 22.1 0.1 0.0029 17.6 0.0 2.7 2 1 1 3 3 3 1 PAS fold PAS_3 PF08447.12 ORY75693.1 - 0.00043 20.5 0.0 0.0008 19.6 0.0 1.4 1 0 0 1 1 1 1 PAS fold APH PF01636.23 ORY75693.1 - 0.0005 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY75693.1 - 0.011 14.7 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 ORY75693.1 - 0.015 14.9 0.1 0.6 9.7 0.0 2.5 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY75693.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 ORY75693.1 - 0.048 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CIAPIN1 PF05093.13 ORY75695.1 - 7.3e-28 97.0 4.5 1.3e-27 96.2 4.5 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 ORY75695.1 - 9.8e-08 32.3 0.0 1.6e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus FHA PF00498.26 ORY75697.1 - 6.9e-10 39.1 0.0 9.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain DUF4761 PF15958.5 ORY75697.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) Yop-YscD_cpl PF16697.5 ORY75697.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain F-box-like PF12937.7 ORY75698.1 - 0.041 13.8 0.9 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 F-box-like Glyco_transf_90 PF05686.12 ORY75703.1 - 1.1e-39 136.5 0.3 2.2e-39 135.5 0.3 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 LRR_8 PF13855.6 ORY75704.1 - 2.4e-12 46.4 14.6 1.4e-07 31.1 2.9 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY75704.1 - 8e-06 26.1 9.3 0.00037 20.8 0.9 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Pyridox_oxase_2 PF12766.7 ORY75704.1 - 0.2 12.3 0.1 0.46 11.1 0.1 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Metallophos PF00149.28 ORY75705.1 - 3.2e-10 40.8 0.0 7.8e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY75705.1 - 0.00032 20.9 0.1 0.006 16.8 0.0 2.3 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Nop14 PF04147.12 ORY75705.1 - 6 4.9 15.6 8.5 4.5 15.6 1.1 1 0 0 1 1 1 0 Nop14-like family IBR PF01485.21 ORY75706.1 - 8.2e-10 38.8 26.8 5.3e-07 29.8 7.2 4.6 4 1 0 4 4 4 3 IBR domain, a half RING-finger domain RAP1 PF07218.11 ORY75706.1 - 0.17 10.2 2.3 0.24 9.6 2.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EF-hand_1 PF00036.32 ORY75707.1 - 8.9e-21 71.8 0.5 0.00014 21.2 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORY75707.1 - 4.9e-20 69.7 2.1 1.7e-05 24.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 ORY75707.1 - 5.4e-17 62.0 2.6 1.7e-08 34.8 0.1 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY75707.1 - 1.1e-16 59.4 1.7 0.00037 19.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY75707.1 - 2.3e-12 46.6 1.3 2.8e-07 30.3 0.1 4.0 3 1 1 4 4 4 4 EF-hand domain pair DNA_mis_repair PF01119.19 ORY75708.1 - 6.4e-15 54.9 0.0 5.2e-08 32.6 0.1 2.4 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY75708.1 - 4.1e-09 36.4 0.0 9.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY75708.1 - 2e-06 28.3 0.0 6e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 ORY75708.1 - 0.00033 20.5 0.1 0.0059 16.4 0.0 3.0 4 0 0 4 4 4 1 MutL C terminal dimerisation domain ORMDL PF04061.14 ORY75709.1 - 9e-50 168.0 2.4 1.1e-49 167.7 2.4 1.1 1 0 0 1 1 1 1 ORMDL family ParA PF10609.9 ORY75710.1 - 4.5e-77 258.8 0.1 6.2e-77 258.4 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY75710.1 - 6.9e-08 32.6 0.0 2e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY75710.1 - 3.2e-05 23.9 0.3 0.0013 18.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 ORY75710.1 - 0.0013 18.0 5.3 0.0059 15.8 1.4 2.5 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 ORY75710.1 - 0.0018 17.6 0.9 0.0048 16.2 0.1 1.9 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.6 ORY75710.1 - 0.0046 16.8 0.2 0.58 9.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY75710.1 - 0.068 12.7 0.5 0.15 11.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain Cyclin_N PF00134.23 ORY75711.1 - 9.9e-08 31.8 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY75711.1 - 0.00045 20.6 0.8 0.00073 19.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin SOG2 PF10428.9 ORY75711.1 - 0.007 15.6 8.4 0.0089 15.3 8.4 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein FAM220 PF15487.6 ORY75711.1 - 0.39 10.3 2.2 0.52 9.9 2.2 1.2 1 0 0 1 1 1 0 FAM220 family AAA PF00004.29 ORY75712.1 - 8.9e-95 314.1 0.0 1.5e-46 158.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY75712.1 - 3.4e-22 78.0 12.7 3.9e-11 42.6 0.7 3.5 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 ORY75712.1 - 7.3e-20 70.9 0.5 3.6e-19 68.7 0.5 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ORY75712.1 - 1.5e-13 50.8 0.0 2.2e-05 24.2 0.0 3.2 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY75712.1 - 6.4e-13 49.2 0.1 1.6e-07 31.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY75712.1 - 2.5e-11 43.9 0.0 1.3e-05 25.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY75712.1 - 7.5e-11 42.2 0.6 5.5e-05 23.2 0.0 3.5 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY75712.1 - 2.1e-10 41.2 0.9 0.00093 19.6 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain TIP49 PF06068.13 ORY75712.1 - 4.1e-09 36.1 0.0 0.0016 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 ORY75712.1 - 8e-09 35.9 0.2 0.051 13.8 0.0 4.0 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 ORY75712.1 - 1.7e-08 34.1 0.0 3.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Vps4_C PF09336.10 ORY75712.1 - 2.6e-08 33.8 0.3 6.8e-07 29.2 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 ORY75712.1 - 1.9e-07 31.0 0.0 0.011 15.5 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY75712.1 - 4.6e-07 29.4 0.4 0.027 13.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY75712.1 - 5.7e-07 30.1 0.0 0.029 14.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ORY75712.1 - 1.3e-06 28.5 0.0 0.017 15.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 ORY75712.1 - 1.5e-06 28.5 0.0 0.024 15.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase ATPase PF06745.13 ORY75712.1 - 1.7e-06 27.5 0.2 0.78 9.0 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_28 PF13521.6 ORY75712.1 - 5.9e-06 26.6 0.4 0.21 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 ORY75712.1 - 5.9e-06 25.6 0.1 0.0059 15.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 ORY75712.1 - 6.5e-06 25.8 0.1 0.024 14.1 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 ORY75712.1 - 1e-05 26.1 0.0 0.12 12.9 0.0 3.9 3 1 0 3 3 2 1 ABC transporter AAA_25 PF13481.6 ORY75712.1 - 1.9e-05 24.3 0.6 0.28 10.7 0.0 3.6 2 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 ORY75712.1 - 2.7e-05 23.9 0.0 0.39 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.6 ORY75712.1 - 3.7e-05 23.5 0.1 0.44 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 ORY75712.1 - 9.1e-05 22.0 0.2 0.38 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_17 PF13207.6 ORY75712.1 - 0.00015 22.2 0.0 0.72 10.3 0.0 3.2 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 ORY75712.1 - 0.00019 21.4 0.0 0.46 10.3 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein TsaE PF02367.17 ORY75712.1 - 0.00025 21.0 0.0 0.29 11.1 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 ORY75712.1 - 0.00029 20.9 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 ORY75712.1 - 0.00034 20.5 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORY75712.1 - 0.00048 19.4 0.0 0.083 12.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 ORY75712.1 - 0.0005 19.9 1.2 1.3 8.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF2075 PF09848.9 ORY75712.1 - 0.00086 18.6 0.0 0.49 9.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 ORY75712.1 - 0.0018 18.7 1.6 2.8 8.3 0.0 4.1 4 1 0 5 5 3 1 AAA domain AAA_30 PF13604.6 ORY75712.1 - 0.0021 17.8 0.3 2.3 7.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 ORY75712.1 - 0.0037 17.2 0.3 0.79 9.6 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Sigma54_activ_2 PF14532.6 ORY75712.1 - 0.0038 17.3 0.0 4.7 7.3 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 ORY75712.1 - 0.0057 15.9 0.0 3.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.18 ORY75712.1 - 0.0061 16.3 0.0 0.88 9.3 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 ORY75712.1 - 0.0094 15.9 0.1 12 5.8 0.0 3.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ORY75712.1 - 0.015 14.5 0.0 0.76 8.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 ORY75712.1 - 0.02 14.0 0.0 0.73 8.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 ORY75712.1 - 0.034 14.0 0.4 6.9 6.5 0.0 3.6 3 0 0 3 3 3 0 NTPase IPT PF01745.16 ORY75712.1 - 0.042 13.2 0.0 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 ORY75712.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 ORY75712.1 - 0.083 12.6 1.1 9.3 5.9 0.0 3.1 4 0 0 4 4 2 0 Cytidylate kinase PIF1 PF05970.14 ORY75712.1 - 0.14 11.3 0.0 11 5.0 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase KAP_NTPase PF07693.14 ORY75712.1 - 0.14 11.3 0.0 2.6 7.2 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain Hydin_ADK PF17213.3 ORY75712.1 - 0.52 10.6 6.0 67 3.7 0.0 3.9 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain Ribosomal_S7e PF01251.18 ORY75713.1 - 1.9e-79 265.7 0.4 2.1e-79 265.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e ATP_transf PF09830.9 ORY75714.1 - 5e-14 52.2 0.0 9e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 ORY75714.1 - 0.068 12.9 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) HIT PF01230.23 ORY75714.1 - 0.13 13.0 0.1 1.3 9.8 0.0 2.3 2 0 0 2 2 2 0 HIT domain p450 PF00067.22 ORY75715.1 - 1.1e-25 90.4 0.0 1.1e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Peptidase_M16_C PF05193.21 ORY75716.1 - 5.9e-20 72.0 0.0 6e-16 59.0 0.0 3.0 2 1 1 3 3 3 2 Peptidase M16 inactive domain M16C_assoc PF08367.11 ORY75716.1 - 0.35 10.0 1.3 1.2 8.2 0.8 1.9 2 0 0 2 2 2 0 Peptidase M16C associated RNA_pol_Rpb1_1 PF04997.12 ORY75925.1 - 1.6e-80 270.8 0.0 2.6e-80 270.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 ORY75925.1 - 5.3e-75 251.2 0.0 8.8e-75 250.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 ORY75925.1 - 5.4e-69 232.6 0.0 8e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 ORY75925.1 - 1.1e-67 227.6 0.2 4.8e-67 225.5 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 ORY75925.1 - 1.4e-50 171.3 0.0 3.3e-50 170.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY75925.1 - 6.7e-38 129.0 0.1 1.2e-37 128.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 adh_short PF00106.25 ORY75926.1 - 1.1e-40 139.2 0.0 1.5e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY75926.1 - 2.3e-28 99.3 0.0 3e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY75926.1 - 5.6e-10 39.4 0.0 8.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 ORY75926.1 - 1.5e-05 24.7 0.2 0.019 14.5 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 ORY75926.1 - 2.2e-05 24.4 0.2 3.9e-05 23.6 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY75926.1 - 0.0017 17.9 0.1 0.0038 16.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY75926.1 - 0.019 14.1 0.2 0.21 10.7 0.1 2.3 1 1 1 2 2 2 0 Male sterility protein DUF1776 PF08643.10 ORY75926.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 ORY75926.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY75926.1 - 0.19 10.7 0.1 0.25 10.3 0.1 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HMG_box PF00505.19 ORY75927.1 - 2.6e-12 47.0 1.1 5e-12 46.1 1.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY75927.1 - 0.0012 19.3 0.7 0.0031 18.1 0.2 1.9 2 0 0 2 2 2 1 HMG-box domain SPO22 PF08631.10 ORY75928.1 - 3.1e-16 59.7 0.3 3.1e-16 59.7 0.3 2.9 2 1 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like Macoilin PF09726.9 ORY75928.1 - 0.013 14.1 0.1 0.023 13.3 0.1 1.3 1 0 0 1 1 1 0 Macoilin family DUF3632 PF12311.8 ORY75928.1 - 0.019 15.4 1.3 4 7.8 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3632) TPR_1 PF00515.28 ORY75928.1 - 1.2 9.0 4.8 2.4 8.1 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY75928.1 - 3.9 7.9 4.7 14 6.2 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ILVD_EDD PF00920.21 ORY75929.1 - 1.3e-205 683.9 0.2 1.5e-205 683.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Succ_CoA_lig PF13607.6 ORY75929.1 - 0.043 13.6 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Polysacc_deac_1 PF01522.21 ORY75930.1 - 9.7e-29 99.8 0.0 1.6e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY75930.1 - 0.22 10.7 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF4379 PF14311.6 ORY75930.1 - 0.44 10.9 3.1 0.48 10.8 1.6 1.8 2 0 0 2 2 2 0 Probable Zinc-ribbon domain Sel1 PF08238.12 ORY75931.1 - 7e-11 42.4 12.0 0.00047 20.8 1.2 4.5 4 1 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.17 ORY75931.1 - 0.017 15.2 4.4 0.022 14.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY75931.1 - 0.024 14.5 4.7 0.054 13.3 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Integrin_beta PF00362.18 ORY75931.1 - 0.094 12.4 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Integrin beta chain VWA domain IMPDH PF00478.25 ORY75933.1 - 1.2e-132 442.1 2.8 1.4e-132 441.9 2.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ORY75933.1 - 3.3e-13 49.8 0.0 7.3e-08 32.7 0.0 2.8 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.18 ORY75933.1 - 4.7e-10 39.0 1.3 1.2e-09 37.6 1.3 1.7 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 ORY75933.1 - 1.4e-07 31.2 13.2 3.8e-06 26.5 2.0 3.2 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 ORY75933.1 - 2e-06 27.4 0.5 2e-06 27.4 0.5 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 ORY75933.1 - 0.00036 19.9 1.6 0.00097 18.5 1.6 1.7 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 ORY75933.1 - 0.0018 17.4 2.1 0.17 10.9 0.1 2.4 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) Aldolase PF01081.19 ORY75933.1 - 0.016 14.7 2.9 0.019 14.4 0.1 2.4 3 0 0 3 3 3 0 KDPG and KHG aldolase G3P_antiterm PF04309.12 ORY75933.1 - 0.067 12.6 0.7 0.57 9.6 0.1 2.2 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Glu_synthase PF01645.17 ORY75933.1 - 0.37 9.9 4.2 0.71 8.9 4.2 1.4 1 0 0 1 1 1 0 Conserved region in glutamate synthase GCP_C_terminal PF04130.13 ORY75934.1 - 8.6e-50 169.9 0.0 1.2e-49 169.4 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORY75934.1 - 1.4e-09 38.0 0.0 3.1e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal PXA PF02194.15 ORY75935.1 - 1.4e-47 162.0 1.4 2.1e-47 161.5 0.4 1.8 2 0 0 2 2 2 1 PXA domain HAD_2 PF13419.6 ORY75936.1 - 2.1e-19 70.3 0.0 2.8e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY75936.1 - 2e-10 41.3 0.1 2.3e-09 37.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY75936.1 - 0.005 17.3 0.0 0.0067 16.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY75936.1 - 0.028 14.5 0.0 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase 3HCDH PF00725.22 ORY75936.1 - 0.079 13.6 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain HSF_DNA-bind PF00447.17 ORY75937.1 - 6e-28 97.3 0.2 8.2e-28 96.9 0.2 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Peptidase_S21 PF00716.17 ORY75937.1 - 0.2 11.3 4.8 0.26 10.9 4.8 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Cyclin PF08613.11 ORY75938.1 - 4.4e-06 27.2 0.0 1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY75938.1 - 3.4e-05 23.6 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain tRNA-synt_1b PF00579.25 ORY75939.1 - 6.5e-21 74.9 0.0 9.9e-14 51.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) DUF3860 PF12976.7 ORY75939.1 - 0.094 12.7 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Allantoicase PF03561.15 ORY75940.1 - 6.6e-80 266.1 0.0 3.9e-41 140.4 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 ORY75940.1 - 1.8e-43 148.5 0.0 3.7e-43 147.5 0.0 1.4 2 0 0 2 2 2 1 Ureidoglycolate lyase DUF938 PF06080.12 ORY75941.1 - 6.6e-30 104.4 0.0 8.3e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 ORY75941.1 - 2.8e-08 33.8 0.0 3.9e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY75941.1 - 8e-05 23.3 0.0 0.00026 21.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY75941.1 - 0.00018 22.2 0.0 0.0003 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ORY75941.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 ORY75941.1 - 0.0055 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORY75941.1 - 0.0065 17.1 0.0 0.016 15.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY75941.1 - 0.093 12.5 0.0 0.42 10.4 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain START PF01852.19 ORY75942.1 - 4.9e-16 58.8 0.0 1.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 START domain DUF3704 PF12488.8 ORY75942.1 - 0.15 11.7 0.5 0.47 10.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) TRI12 PF06609.13 ORY75943.1 - 1.8e-28 99.3 22.2 2.3e-28 99.0 22.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY75943.1 - 2.5e-16 59.6 41.5 2.5e-16 59.6 41.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily PrgI PF12666.7 ORY75943.1 - 7 7.4 23.1 3.6 8.4 0.1 5.4 5 2 1 6 6 6 0 PrgI family protein DUF4482 PF14818.6 ORY75944.1 - 0.041 14.8 0.1 0.047 14.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Porphobil_deam PF01379.20 ORY75946.1 - 4.5e-73 245.1 0.0 5.9e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ORY75946.1 - 4.7e-12 46.1 0.3 1.3e-10 41.5 0.3 2.5 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain adh_short_C2 PF13561.6 ORY75947.1 - 4e-46 157.5 0.1 5.3e-46 157.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY75947.1 - 4.8e-45 153.4 0.2 6.7e-45 153.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY75947.1 - 6.4e-07 29.5 1.1 7.6e-07 29.2 0.1 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 ORY75947.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Ribonuc_2-5A PF06479.12 ORY75948.1 - 8e-45 152.1 0.0 1.2e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 ORY75948.1 - 9.8e-43 146.4 0.0 1e-31 110.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY75948.1 - 1.7e-20 73.4 0.0 4.5e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY75948.1 - 2.2e-05 23.4 0.0 3.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY75948.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.21 ORY75948.1 - 0.018 14.9 0.3 11 6.2 0.0 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat YrbL-PhoP_reg PF10707.9 ORY75948.1 - 0.097 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL cEGF PF12662.7 ORY75950.1 - 0.7 9.9 17.2 0.76 9.8 2.9 3.1 3 0 0 3 3 3 0 Complement Clr-like EGF-like Antistasin PF02822.14 ORY75950.1 - 1.6 9.4 23.5 15 6.3 7.1 4.6 3 1 0 3 3 3 0 Antistasin family SPX PF03105.19 ORY75950.1 - 2.1 8.2 6.7 2.3 8.1 6.7 1.1 1 0 0 1 1 1 0 SPX domain F-box-like PF12937.7 ORY75951.1 - 3.7e-07 29.9 1.7 8.1e-07 28.8 1.7 1.6 1 0 0 1 1 1 1 F-box-like TBP PF00352.21 ORY75952.1 - 4.3e-67 222.1 0.7 1.3e-32 111.6 0.1 2.6 3 0 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 ORY75952.1 - 3.7e-06 26.9 0.9 0.036 14.2 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 ORY75952.1 - 0.12 12.2 0.1 0.97 9.3 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Bromodomain PF00439.25 ORY75954.1 - 1.2e-34 118.2 0.4 5.8e-16 58.3 0.1 3.4 2 1 0 2 2 2 2 Bromodomain BET PF17035.5 ORY75954.1 - 5.1e-19 68.2 0.1 9.8e-19 67.3 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Cwf_Cwc_15 PF04889.12 ORY75954.1 - 9 6.0 13.3 1.9 8.2 1.7 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Arrestin_C PF02752.22 ORY75955.1 - 0.002 18.6 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY75955.1 - 0.013 15.5 0.0 0.035 14.2 0.0 1.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF1677 PF07911.13 ORY75956.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) DUF3546 PF12066.8 ORY75956.1 - 0.19 12.0 2.3 0.51 10.6 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3546) 4HBT PF03061.22 ORY75957.1 - 2.7e-13 50.1 0.3 3.9e-13 49.6 0.3 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 ORY75957.1 - 0.032 14.5 0.0 0.041 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily GrpE PF01025.19 ORY75958.1 - 2e-46 157.7 0.0 2.5e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 GrpE Sec20 PF03908.13 ORY75959.1 - 5.2e-18 64.8 1.1 5.2e-18 64.8 1.1 2.0 2 0 0 2 2 2 1 Sec20 DUF953 PF06110.11 ORY75960.1 - 1.2e-16 60.3 0.2 1.5e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Nucleotid_trans PF03407.16 ORY75961.1 - 7.7e-07 29.3 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Peptidase_M50B PF13398.6 ORY75962.1 - 6.3e-54 182.7 19.4 7.8e-54 182.3 19.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Hydrolase_6 PF13344.6 ORY75963.1 - 1.1e-22 80.1 0.0 1.4e-21 76.4 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY75963.1 - 2.5e-22 78.7 0.0 1.9e-21 75.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY75963.1 - 0.028 14.7 0.3 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HbrB PF08539.11 ORY75964.1 - 2.9e-40 138.0 0.0 5.7e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 HbrB-like PHD PF00628.29 ORY75965.1 - 3.3e-10 39.7 9.8 5.6e-10 39.0 9.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY75965.1 - 1.9e-05 24.1 2.4 3e-05 23.5 2.4 1.3 1 0 0 1 1 1 1 PHD-finger DUF4633 PF15464.6 ORY75965.1 - 0.0042 17.2 1.0 0.096 12.8 0.7 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4633) 4PPT_N PF17837.1 ORY75965.1 - 0.01 16.0 0.5 0.036 14.2 0.5 1.9 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain zf-CW PF07496.15 ORY75965.1 - 0.4 10.7 4.5 0.96 9.5 4.5 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Mem_trans PF03547.18 ORY75966.1 - 1.9e-21 75.9 0.0 6e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 Membrane transport protein DUF3306 PF11748.8 ORY75966.1 - 2.4 9.0 4.3 4.7 8.1 3.3 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) AMP-binding PF00501.28 ORY75967.1 - 3.3e-90 302.7 0.1 4e-90 302.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY75967.1 - 5.7e-26 91.3 0.9 4.5e-25 88.4 0.2 2.7 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORY75967.1 - 1.9e-21 75.7 6.1 1e-20 73.4 0.4 2.9 3 0 0 3 3 3 2 Acetyl-coenzyme A synthetase N-terminus RDD PF06271.12 ORY75968.1 - 0.04 14.1 0.7 0.04 14.1 0.7 2.6 2 1 0 2 2 2 0 RDD family IF4E PF01652.18 ORY75969.1 - 3.2e-06 27.0 0.0 3.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TT_ORF1 PF02956.14 ORY75970.1 - 9 4.8 23.2 12 4.4 23.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 UQ_con PF00179.26 ORY75972.1 - 3.6e-25 88.2 0.0 4.3e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nfu_N PF08712.11 ORY75973.1 - 7.7e-31 106.0 0.0 1.9e-30 104.8 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORY75973.1 - 1.8e-27 95.3 0.1 2.9e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain RFC1 PF08519.12 ORY75974.1 - 1.3e-61 207.3 0.0 5.1e-61 205.4 0.0 1.9 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 ORY75974.1 - 2.5e-14 53.4 0.0 7.6e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 ORY75974.1 - 1.7e-12 47.9 0.0 4.5e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY75974.1 - 2.3e-09 37.4 0.0 5.4e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 ORY75974.1 - 0.00065 20.1 0.0 0.0015 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ORY75974.1 - 0.0007 19.6 0.0 0.0018 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY75974.1 - 0.0012 19.4 0.8 0.0043 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY75974.1 - 0.0023 17.7 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 ORY75974.1 - 0.0027 17.6 0.0 0.067 13.1 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 ORY75974.1 - 0.005 17.1 0.0 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY75974.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY75974.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY75974.1 - 0.047 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY75974.1 - 0.05 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ORY75974.1 - 0.075 13.0 0.0 0.35 10.8 0.0 2.1 1 1 0 1 1 1 0 NACHT domain SCAN PF02023.17 ORY75975.1 - 0.0012 18.6 0.3 0.63 9.9 0.0 2.7 3 0 0 3 3 3 2 SCAN domain DMA PF03474.14 ORY75975.1 - 0.21 11.2 0.1 3.8 7.2 0.0 2.7 3 0 0 3 3 3 0 DMRTA motif Rgp1 PF08737.10 ORY75976.1 - 2e-93 313.9 0.0 2.8e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 ORY75976.1 - 0.00014 21.9 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY75976.1 - 0.0002 21.8 0.0 0.21 12.0 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.11 ORY75976.1 - 0.083 12.4 0.0 4.8 6.7 0.0 2.2 2 0 0 2 2 2 0 SpoOM protein F-box-like PF12937.7 ORY75977.1 - 1.2e-05 25.0 3.0 1.7e-05 24.6 3.0 1.2 1 0 0 1 1 1 1 F-box-like MSA-2c PF12238.8 ORY75979.1 - 0.12 12.3 3.1 0.16 12.0 3.1 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c MCLC PF05934.11 ORY75979.1 - 0.13 11.0 0.6 0.15 10.7 0.6 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) NAD_Gly3P_dh_N PF01210.23 ORY75981.1 - 2.1e-42 144.7 0.0 3e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORY75981.1 - 2.5e-41 141.3 0.0 3.7e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 ORY75981.1 - 8.3e-05 23.1 0.1 0.0031 18.0 0.1 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 ORY75981.1 - 0.11 12.9 0.0 0.47 10.9 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Rossmann-like PF10727.9 ORY75981.1 - 0.12 12.2 0.1 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 Rossmann-like domain ORC6 PF05460.13 ORY75981.1 - 8.7 5.5 5.7 12 5.0 5.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NUC153 PF08159.12 ORY75982.1 - 2.4e-12 46.4 16.6 1.2e-09 37.7 2.6 3.6 3 0 0 3 3 3 3 NUC153 domain Mito_carr PF00153.27 ORY75983.1 - 6e-28 96.6 0.6 1.5e-12 47.3 0.0 3.4 2 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY75983.1 - 0.12 11.5 0.0 0.39 9.8 0.0 1.9 2 1 0 2 2 2 0 Gammaproteobacterial serine protease LSM PF01423.22 ORY75984.1 - 1e-16 60.3 0.6 1.4e-16 59.9 0.6 1.2 1 0 0 1 1 1 1 LSM domain Toxin_32 PF08120.11 ORY75985.1 - 0.12 12.2 2.3 0.37 10.6 2.3 1.8 1 0 0 1 1 1 0 Tamulustoxin family 7TM_GPCR_Sri PF10327.9 ORY75985.1 - 7.2 5.7 12.2 3.1 6.9 4.4 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sri CDC50 PF03381.15 ORY75987.1 - 6e-99 331.1 0.0 9.6e-99 330.4 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3185 PF11381.8 ORY75987.1 - 0.11 12.6 4.3 0.12 12.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Ras PF00071.22 ORY75989.1 - 1.5e-56 190.5 0.1 1.8e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY75989.1 - 8.4e-33 113.1 0.0 1.2e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY75989.1 - 3.4e-13 49.4 0.0 3.8e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY75989.1 - 1.4e-07 31.6 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY75989.1 - 8.2e-06 25.3 0.0 1.1e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY75989.1 - 1.2e-05 25.0 0.0 0.00051 19.6 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY75989.1 - 0.00029 20.8 0.1 0.0051 16.7 0.1 2.2 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 ORY75989.1 - 0.00068 19.5 0.2 0.033 14.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 ORY75989.1 - 0.0017 17.7 0.1 0.037 13.3 0.0 2.1 2 0 0 2 2 2 1 Septin cobW PF02492.19 ORY75989.1 - 0.0018 17.9 0.0 0.0056 16.3 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 ORY75989.1 - 0.0039 16.9 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ORY75989.1 - 0.0066 16.7 0.0 0.017 15.4 0.0 1.7 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.10 ORY75989.1 - 0.0076 15.7 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY75989.1 - 0.014 15.8 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 ORY75989.1 - 0.017 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORY75989.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY75989.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 ORY75989.1 - 0.048 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 ORY75989.1 - 0.068 13.1 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 ORY75989.1 - 0.089 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 ORY75989.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein KH_8 PF17903.1 ORY75990.1 - 0.00027 21.0 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ORY75990.1 - 0.031 14.1 0.5 0.057 13.2 0.5 1.4 1 0 0 1 1 1 0 KH domain Ribosomal_L2_C PF03947.18 ORY75992.1 - 1.8e-44 151.0 6.0 3.1e-44 150.2 6.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY75992.1 - 1.4e-15 57.0 0.0 4.2e-15 55.5 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain 2-Hacid_dh_C PF02826.19 ORY75995.1 - 5.3e-40 136.7 0.0 1.2e-39 135.5 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY75995.1 - 3.5e-08 33.2 0.0 4.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY75995.1 - 0.00018 21.7 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.25 ORY75996.1 - 2.5e-25 89.1 0.1 1.9e-23 82.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY75996.1 - 1.4e-15 57.5 0.1 2.4e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY75996.1 - 6e-09 36.1 0.0 8.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY75996.1 - 0.0067 15.6 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein YqgB PF11036.8 ORY75996.1 - 0.021 14.5 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Virulence promoting factor ArenaCapSnatch PF17296.2 ORY75996.1 - 0.023 14.2 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain Sacchrp_dh_NADP PF03435.18 ORY75996.1 - 0.05 13.9 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain IBR PF01485.21 ORY75997.1 - 8.9e-09 35.5 30.5 2e-07 31.1 4.3 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain ANAPC4_WD40 PF12894.7 ORY75998.1 - 8.7e-14 51.6 0.1 0.011 16.0 0.0 6.1 2 2 1 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY75998.1 - 5.9e-08 33.3 0.0 1.5 9.8 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat SWIRM-assoc_2 PF16496.5 ORY75998.1 - 0.27 10.1 1.7 0.52 9.1 1.7 1.5 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Pkinase PF00069.25 ORY75999.1 - 2.8e-43 148.2 0.4 2.1e-22 79.8 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY75999.1 - 1.1e-12 47.8 0.8 3.9e-09 36.2 0.1 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Peptidase_M20 PF01546.28 ORY76000.1 - 2.2e-34 119.0 0.0 3.2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY76000.1 - 2.7e-08 33.7 0.0 6.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain RRM_2 PF04059.12 ORY76001.1 - 3.5e-26 91.2 0.0 4.1e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 ORY76001.1 - 0.047 13.5 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.15 ORY76002.1 - 2.3e-238 792.1 1.5 5.6e-224 744.6 0.5 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY76002.1 - 1.1e-13 51.6 0.1 6.7e-13 49.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY76002.1 - 2.5e-12 47.1 1.3 2.5e-12 47.1 1.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY76002.1 - 0.0076 15.7 0.1 0.24 10.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 ORY76002.1 - 0.0094 16.1 0.0 0.058 13.5 0.0 2.4 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY76002.1 - 0.039 13.8 0.0 0.41 10.4 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Reprolysin_5 PF13688.6 ORY76003.1 - 2.2e-41 142.2 4.6 2.2e-41 142.2 4.6 2.7 2 1 1 3 3 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 ORY76003.1 - 2.3e-39 135.3 2.6 2.3e-39 135.3 2.6 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORY76003.1 - 6.5e-36 123.9 2.2 1.2e-35 123.0 2.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 ORY76003.1 - 1.7e-16 60.7 25.6 1.7e-16 60.7 25.6 4.4 4 1 0 4 4 2 1 Disintegrin Reprolysin_3 PF13582.6 ORY76003.1 - 1.6e-11 44.8 0.2 1.6e-11 44.8 0.2 2.8 3 1 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 ORY76003.1 - 1.2e-06 28.6 4.7 3.8e-06 26.9 3.7 2.3 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 ORY76003.1 - 0.0012 19.1 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 ORY76003.1 - 0.012 16.2 11.4 0.012 16.2 11.4 3.8 2 1 1 3 3 1 0 ADAM cysteine-rich domain Peptidase_M10 PF00413.24 ORY76003.1 - 0.053 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 ORY76003.1 - 0.058 12.3 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M54 PF07998.11 ORY76003.1 - 0.079 12.9 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M54 Zincin_1 PF06262.11 ORY76003.1 - 0.1 12.7 0.1 0.34 11.0 0.1 1.8 1 0 0 1 1 1 0 Zincin-like metallopeptidase BC10 PF06726.12 ORY76005.1 - 8.1e-09 35.6 9.6 1.2e-08 35.0 9.3 1.5 1 1 0 1 1 1 1 Bladder cancer-related protein BC10 MFS_1 PF07690.16 ORY76006.1 - 1.6e-19 70.0 49.2 1.2e-18 67.1 46.9 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidase PF01425.21 ORY76007.1 - 3.3e-98 329.6 0.0 6.7e-98 328.6 0.0 1.5 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 ORY76008.1 - 2.5e-23 82.6 39.2 3.8e-23 82.0 39.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CDH-cyt PF16010.5 ORY76009.1 - 7.9e-06 25.7 0.1 2.1e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 ORY76009.1 - 0.0016 18.6 2.9 0.0016 18.6 2.9 2.2 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF1345 PF07077.11 ORY76009.1 - 0.064 13.0 0.1 0.24 11.1 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF2306 PF10067.9 ORY76009.1 - 0.095 12.9 5.9 2.4 8.4 0.3 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) DUF4079 PF13301.6 ORY76009.1 - 0.61 10.2 13.2 0.034 14.3 2.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Zn_clus PF00172.18 ORY76010.1 - 2.4e-05 24.3 7.6 4e-05 23.6 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 ORY76011.1 - 1.6e-44 152.2 0.0 2.1e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD-oxidase_C PF02913.19 ORY76012.1 - 5e-50 170.5 0.0 7.4e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY76012.1 - 3.2e-28 98.2 0.1 2e-19 69.7 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DUF1485 PF07364.12 ORY76012.1 - 0.054 12.8 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase family M81 Sulfatase PF00884.23 ORY76013.1 - 1.4e-49 169.2 0.0 1.9e-49 168.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase BioT2 PF15368.6 ORY76013.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Spermatogenesis family BioT2 SNF2_N PF00176.23 ORY76015.1 - 4.5e-70 236.1 0.2 4.5e-70 236.1 0.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY76015.1 - 5.5e-22 78.2 0.1 2.2e-18 66.6 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain HSA PF07529.13 ORY76015.1 - 2.6e-17 62.9 9.1 2.6e-17 62.9 9.1 3.3 3 0 0 3 3 3 1 HSA Bromodomain PF00439.25 ORY76015.1 - 7.6e-17 61.2 0.0 1.9e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 ORY76015.1 - 2.6e-15 55.9 1.0 9.7e-15 54.0 1.0 2.1 1 0 0 1 1 1 1 QLQ SnAC PF14619.6 ORY76015.1 - 6.4e-11 42.7 2.8 6.4e-11 42.7 2.8 4.1 6 0 0 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 ORY76015.1 - 3.4e-10 40.2 2.8 6.6e-10 39.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BTV_NS2 PF04514.12 ORY76015.1 - 0.04 12.7 1.1 0.095 11.5 1.1 1.6 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spt20 PF12090.8 ORY76015.1 - 0.31 10.6 13.2 0.79 9.3 13.2 1.6 1 0 0 1 1 1 0 Spt20 family Glucosamine_iso PF01182.20 ORY76016.1 - 5.6e-74 248.8 0.0 6.4e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase bZIP_1 PF00170.21 ORY76017.1 - 0.02 15.0 9.2 0.034 14.2 9.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor DUF4519 PF15012.6 ORY76017.1 - 0.43 10.8 3.9 0.96 9.7 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) 6PF2K PF01591.18 ORY76206.1 - 1.8e-42 145.1 1.1 2.4e-42 144.7 1.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY76206.1 - 1.1e-26 93.8 0.0 7.2e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DER1 PF04511.15 ORY76207.1 - 5.6e-43 147.1 0.5 7.3e-43 146.7 0.5 1.1 1 0 0 1 1 1 1 Der1-like family Serpentine_r_xa PF03383.15 ORY76207.1 - 0.036 14.0 0.4 0.053 13.5 0.4 1.2 1 0 0 1 1 1 0 Caenorhabditis serpentine receptor-like protein, class xa NTP_transf_9 PF04248.12 ORY76209.1 - 1.9e-29 101.4 0.8 5.7e-29 99.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF427) VWA PF00092.28 ORY76210.1 - 3.7e-10 40.3 0.0 6.2e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY76210.1 - 3.7e-08 34.0 0.0 8.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.18 ORY76210.1 - 0.029 14.0 0.0 0.065 12.9 0.0 1.5 2 0 0 2 2 2 0 Integrin beta chain VWA domain EF_assoc_2 PF08356.12 ORY76211.1 - 2.3e-29 101.2 0.0 5e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 ORY76211.1 - 8.5e-29 99.0 3.2 1.3e-28 98.4 0.6 2.3 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 ORY76211.1 - 3.3e-27 95.1 0.0 2.8e-21 75.8 0.0 2.9 2 1 0 2 2 2 2 Ras family Roc PF08477.13 ORY76211.1 - 1.5e-14 54.2 0.0 5.4e-10 39.5 0.0 3.3 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 ORY76211.1 - 2.3e-08 33.0 2.8 0.00049 19.5 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY76211.1 - 2.8e-08 33.0 1.7 0.00076 19.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORY76211.1 - 4.1e-07 30.4 0.0 0.033 14.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.23 ORY76211.1 - 6.1e-07 29.5 0.2 0.00017 21.6 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY76211.1 - 4.5e-06 27.0 0.1 0.033 14.5 0.0 2.8 3 1 0 3 3 2 2 AAA domain EF-hand_5 PF13202.6 ORY76211.1 - 8.5e-06 25.0 3.4 0.0018 17.7 0.1 2.6 2 0 0 2 2 2 2 EF hand NACHT PF05729.12 ORY76211.1 - 4.1e-05 23.6 0.8 0.53 10.2 1.5 2.8 2 0 0 2 2 2 2 NACHT domain Arf PF00025.21 ORY76211.1 - 6.7e-05 22.4 0.3 0.28 10.6 0.1 3.6 2 2 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 ORY76211.1 - 0.00065 20.1 1.5 0.8 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY76211.1 - 0.001 19.0 2.0 0.068 13.1 0.0 3.4 4 0 0 4 4 4 1 RsgA GTPase SRPRB PF09439.10 ORY76211.1 - 0.0012 18.4 0.0 0.055 12.9 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ORY76211.1 - 0.0014 19.2 0.5 0.35 11.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 ORY76211.1 - 0.0056 16.4 0.8 0.18 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY76211.1 - 0.0097 15.6 0.3 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY76211.1 - 0.016 14.8 0.0 6.9 6.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain SPARC_Ca_bdg PF10591.9 ORY76211.1 - 0.017 15.4 0.8 2.9 8.2 0.0 2.6 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region RNA_helicase PF00910.22 ORY76211.1 - 0.018 15.4 0.2 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.27 ORY76211.1 - 0.023 14.3 0.0 30 4.1 0.0 3.5 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 ORY76211.1 - 0.033 14.1 0.3 3.3 7.5 0.1 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 ORY76211.1 - 0.043 13.5 0.8 2.4 7.9 1.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 ORY76211.1 - 0.044 13.3 0.2 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region EF-hand_4 PF12763.7 ORY76211.1 - 0.045 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Septin PF00735.18 ORY76211.1 - 0.083 12.2 0.2 0.87 8.8 0.0 2.1 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 ORY76211.1 - 0.11 12.3 4.1 20 4.8 0.5 3.7 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA PF00004.29 ORY76211.1 - 0.12 12.8 0.9 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 ORY76211.1 - 0.13 12.3 2.6 0.35 10.9 0.0 2.6 3 0 0 3 3 3 0 Dynamin family AAA_18 PF13238.6 ORY76211.1 - 0.15 12.6 0.4 5.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY76211.1 - 0.16 11.9 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NOG1 PF06858.14 ORY76211.1 - 0.19 11.5 0.3 16 5.3 0.1 2.6 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) FtsK_SpoIIIE PF01580.18 ORY76211.1 - 0.22 10.8 0.2 13 5.0 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Adeno_IVa2 PF02456.15 ORY76211.1 - 0.23 10.2 0.6 14 4.4 0.1 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein EF-hand_10 PF14788.6 ORY76211.1 - 0.42 10.5 2.6 0.57 10.1 0.3 2.1 2 0 0 2 2 2 0 EF hand DUF87 PF01935.17 ORY76211.1 - 0.87 9.6 2.3 5.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 ORY76211.1 - 0.97 9.7 3.5 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY76211.1 - 1.7 8.2 3.2 23 4.5 1.1 2.9 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2462 PF09495.10 ORY76212.1 - 3.4e-14 53.3 11.7 4.1e-14 53.1 11.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) HECT PF00632.25 ORY76213.1 - 2.7e-90 303.0 0.0 3.8e-90 302.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-MYND PF01753.18 ORY76215.1 - 0.22 11.6 0.9 0.4 10.8 0.2 1.7 2 0 0 2 2 2 0 MYND finger Ras PF00071.22 ORY76216.1 - 2.4e-50 170.3 0.0 2.8e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY76216.1 - 3.1e-24 85.5 0.0 4.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY76216.1 - 2e-06 27.4 0.0 3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY76216.1 - 0.031 13.7 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY76216.1 - 0.039 14.3 0.1 0.14 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain F-box-like PF12937.7 ORY76218.1 - 1.8e-05 24.6 0.1 4.2e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORY76218.1 - 0.49 10.3 2.8 3.4 7.7 0.1 2.4 2 0 0 2 2 2 0 F-box domain FHA PF00498.26 ORY76220.1 - 3.2e-15 56.2 0.0 5.1e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY76220.1 - 0.0077 16.5 0.0 0.21 11.9 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Apt1 PF10351.9 ORY76220.1 - 4.6 6.0 7.1 4.7 5.9 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C2H2 PF00096.26 ORY76222.1 - 1.8e-08 34.4 13.1 0.00078 19.8 2.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY76222.1 - 2.1e-07 31.0 15.0 0.00025 21.3 4.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY76222.1 - 6.8e-05 23.4 9.9 0.032 15.0 1.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY76222.1 - 0.24 11.7 3.9 2.5 8.5 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding F-box-like PF12937.7 ORY76224.1 - 0.00025 20.9 1.0 0.00055 19.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like Cullin PF00888.22 ORY76226.1 - 1e-186 622.3 13.7 1.6e-186 621.6 13.7 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY76226.1 - 1.1e-25 89.4 1.7 1.1e-25 89.4 1.7 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Mei5 PF10376.9 ORY76226.1 - 0.63 9.9 8.2 0.045 13.6 1.5 2.3 2 1 0 2 2 2 0 Double-strand recombination repair protein F-actin_cap_A PF01267.17 ORY76227.1 - 8e-91 304.2 0.0 9.1e-91 304.0 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit TT_ORF2 PF02957.15 ORY76227.1 - 0.14 13.1 4.6 0.28 12.1 4.6 1.5 1 0 0 1 1 1 0 TT viral ORF2 HA2 PF04408.23 ORY76229.1 - 2.6e-15 56.6 0.1 8.5e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY76229.1 - 9.6e-14 51.7 0.0 2.7e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ORY76229.1 - 7.8e-10 39.0 0.0 3.9e-09 36.7 0.0 2.3 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ORY76229.1 - 3e-08 33.6 0.0 5.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY76229.1 - 0.0062 16.9 0.1 0.019 15.3 0.1 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORY76229.1 - 0.018 15.0 0.0 0.12 12.3 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY76229.1 - 0.026 14.8 0.0 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 ORY76229.1 - 0.087 12.3 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein Herpes_ori_bp PF02399.15 ORY76229.1 - 0.094 10.8 0.0 0.16 10.0 0.0 1.3 1 0 0 1 1 1 0 Origin of replication binding protein Hydin_ADK PF17213.3 ORY76229.1 - 0.1 12.9 0.2 0.83 9.9 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain F-box-like PF12937.7 ORY76231.1 - 0.00031 20.6 0.1 0.0012 18.7 0.1 2.1 1 0 0 1 1 1 1 F-box-like DUF4449 PF14613.6 ORY76232.1 - 3.9e-05 23.8 0.0 3.9e-05 23.8 0.0 4.1 4 1 1 5 5 5 1 Protein of unknown function (DUF4449) ApoLp-III PF07464.11 ORY76232.1 - 0.0043 17.1 2.8 0.0043 17.1 2.8 3.8 4 1 0 4 4 4 1 Apolipophorin-III precursor (apoLp-III) Syntaxin_2 PF14523.6 ORY76232.1 - 4.3 7.8 12.3 12 6.4 0.8 4.3 4 0 0 4 4 4 0 Syntaxin-like protein FA_hydroxylase PF04116.13 ORY76233.1 - 1.4e-17 64.3 13.6 1.4e-17 64.3 13.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF2205 PF10224.9 ORY76234.1 - 3.2e-11 43.1 0.1 3.6e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Short coiled-coil protein CENP-H PF05837.12 ORY76234.1 - 0.053 13.9 0.5 0.068 13.6 0.5 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) RBD-FIP PF09457.10 ORY76234.1 - 0.08 12.9 0.1 0.22 11.5 0.0 1.7 1 1 1 2 2 2 0 FIP domain DivIC PF04977.15 ORY76234.1 - 0.11 12.3 0.4 0.16 11.7 0.4 1.3 1 0 0 1 1 1 0 Septum formation initiator G-patch_2 PF12656.7 ORY76235.1 - 0.017 15.2 0.6 0.017 15.2 0.6 2.8 2 0 0 2 2 2 0 G-patch domain DUF4710 PF15828.5 ORY76235.1 - 0.14 12.3 9.5 2.9 8.1 2.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Menin PF05053.13 ORY76235.1 - 0.53 8.6 15.8 0.7 8.2 15.8 1.1 1 0 0 1 1 1 0 Menin AAA_11 PF13086.6 ORY76235.1 - 7.7 6.2 12.4 0.66 9.7 2.9 2.1 2 0 0 2 2 2 0 AAA domain ThiF PF00899.21 ORY76236.1 - 8.6e-26 90.8 0.0 1.1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Tom22 PF04281.13 ORY76237.1 - 3.1e-34 117.7 0.9 4.6e-34 117.2 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF1414 PF07208.11 ORY76237.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) CTU2 PF10288.9 ORY76238.1 - 1.5e-22 79.9 0.0 2.7e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 F-box-like PF12937.7 ORY76239.1 - 9.1e-07 28.7 0.1 2.5e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like SET PF00856.28 ORY76240.1 - 2.4e-12 47.6 0.0 3e-10 40.7 0.0 2.7 2 1 0 2 2 2 1 SET domain dCMP_cyt_deam_1 PF00383.23 ORY76240.1 - 6.9e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glycos_transf_3 PF00591.21 ORY76241.1 - 6.5e-77 258.5 0.0 8.3e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 ORY76241.1 - 2e-07 30.7 0.0 3.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Pkinase PF00069.25 ORY76243.1 - 1e-68 231.6 0.0 1.4e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY76243.1 - 4.7e-38 130.9 0.0 6.6e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY76243.1 - 3.1e-08 33.3 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY76243.1 - 0.0013 17.7 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY76243.1 - 0.0052 16.2 0.1 0.0089 15.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.23 ORY76244.1 - 1.2e-52 179.3 0.0 1.5e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY76244.1 - 1e-06 29.1 0.4 1.1e-05 25.7 0.4 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY76244.1 - 0.032 14.9 1.9 1.8 9.3 0.0 3.6 4 0 0 4 4 4 0 Aspartyl protease gag-asp_proteas PF13975.6 ORY76244.1 - 0.53 10.9 3.3 4.2 8.0 0.0 3.3 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease RNase_H2_suC PF08615.11 ORY76245.1 - 1.3e-18 67.5 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Allexi_40kDa PF05549.11 ORY76246.1 - 0.031 13.8 6.6 0.051 13.1 6.3 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 ORY76246.1 - 0.053 13.9 3.5 4.3 7.8 0.3 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bcr-Abl_Oligo PF09036.10 ORY76246.1 - 1.2 9.2 5.9 0.64 10.1 2.6 2.2 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 ORY76246.1 - 2.5 6.9 17.2 3.8 6.3 17.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Hemagglutinin PF00509.18 ORY76246.1 - 2.9 6.2 5.4 4 5.7 5.4 1.1 1 0 0 1 1 1 0 Haemagglutinin GTP_CH_N PF12471.8 ORY76247.1 - 1e-89 299.5 0.1 1.4e-89 299.0 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ORY76247.1 - 7.2e-12 45.2 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II XPG_N PF00752.17 ORY76248.1 - 5.1e-34 116.8 0.0 9.9e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORY76248.1 - 3.8e-31 107.3 0.2 9.7e-31 106.0 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 ORY76248.1 - 4.3e-07 30.4 0.0 1.2e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 ORY76248.1 - 0.00059 20.4 0.0 0.0025 18.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 ORY76248.1 - 0.12 12.2 0.1 0.74 9.7 0.0 2.5 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda Ribosomal_L3 PF00297.22 ORY76249.1 - 1.2e-187 623.4 8.7 1.4e-187 623.2 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Big_3_3 PF13750.6 ORY76249.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) Apt1 PF10351.9 ORY76250.1 - 3.2e-117 392.3 1.8 3.2e-117 392.3 1.8 2.6 2 1 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 ORY76250.1 - 3.5e-80 270.2 0.0 1.3e-79 268.4 0.0 1.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 ORY76250.1 - 4.5e-44 150.3 0.0 8.6e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 ORY76250.1 - 4.7e-43 146.8 0.0 1e-42 145.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 ORY76250.1 - 1.8e-28 99.3 0.3 4.9e-27 94.6 0.0 3.7 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain F-box-like PF12937.7 ORY76252.1 - 9.5e-05 22.2 0.0 0.00025 20.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY76252.1 - 0.099 12.6 1.2 0.39 10.7 0.0 2.7 3 0 0 3 3 3 0 F-box domain DHHC PF01529.20 ORY76253.1 - 1.1e-32 112.9 0.5 1.5e-32 112.5 0.5 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2518 PF10726.9 ORY76253.1 - 0.88 9.2 2.3 2.8 7.6 2.8 1.5 2 0 0 2 2 2 0 Protein of function (DUF2518) FYVE PF01363.21 ORY76253.1 - 3.2 8.0 10.6 6.5 7.0 10.6 1.5 1 1 0 1 1 1 0 FYVE zinc finger YccV-like PF08755.11 ORY76254.1 - 0.00012 22.6 0.0 0.00021 21.7 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.7 ORY76254.1 - 0.00069 19.5 0.1 0.0018 18.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY76254.1 - 0.0026 17.6 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain DcuC PF03606.15 ORY76256.1 - 0.21 10.0 0.0 0.27 9.6 0.0 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier PHD PF00628.29 ORY76257.1 - 2.3e-06 27.4 6.3 3.8e-06 26.7 6.3 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 ORY76257.1 - 3.5e-06 27.5 0.0 6.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.6 ORY76257.1 - 0.093 12.3 2.1 0.17 11.5 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 ORY76257.1 - 0.31 11.3 1.8 0.62 10.4 1.8 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hist_deacetyl PF00850.19 ORY76258.1 - 9.7e-63 212.5 0.0 1.2e-62 212.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain IATP PF04568.12 ORY76259.1 - 7.3 7.1 7.5 27 5.3 0.9 3.4 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Sugar_tr PF00083.24 ORY76260.1 - 1.6e-85 287.7 25.8 1.9e-85 287.5 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY76260.1 - 9.8e-16 57.6 30.5 9.8e-16 57.6 30.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ATP_synt_H PF05493.13 ORY76261.1 - 1.6e-21 76.5 0.9 2.1e-21 76.2 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit H PhoR PF11808.8 ORY76261.1 - 0.12 12.9 2.0 0.36 11.3 2.0 1.7 1 1 0 1 1 1 0 Phosphate regulon sensor protein PhoR DUF485 PF04341.12 ORY76261.1 - 0.68 9.9 4.7 0.91 9.5 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF485 AAA_23 PF13476.6 ORY76262.1 - 1.2e-33 117.4 2.1 1.2e-33 117.4 2.1 7.5 1 1 1 3 3 3 1 AAA domain AAA_21 PF13304.6 ORY76262.1 - 4.5e-13 49.7 4.6 6.8e-05 22.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY76262.1 - 1.5e-08 34.8 25.6 6.8e-08 32.6 5.5 5.0 1 1 2 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.6 ORY76262.1 - 6.6e-06 26.3 1.3 0.0002 21.5 0.1 3.2 2 1 1 3 3 3 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 ORY76262.1 - 0.00076 19.0 46.6 0.013 15.0 46.6 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY76262.1 - 0.0017 18.0 0.2 0.0091 15.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY76262.1 - 0.005 17.3 0.0 0.005 17.3 0.0 7.2 4 2 0 4 4 4 1 ABC transporter AAA_16 PF13191.6 ORY76262.1 - 0.13 12.7 0.0 0.13 12.7 0.0 5.2 3 2 0 4 4 4 0 AAA ATPase domain MOZ_SAS PF01853.18 ORY76263.1 - 2.9e-53 180.2 0.0 9.9e-53 178.4 0.0 1.7 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 ORY76263.1 - 1.6e-12 46.8 7.7 1.5e-06 27.7 0.6 2.8 3 0 0 3 3 3 2 MYST family zinc finger domain DHHC PF01529.20 ORY76264.1 - 3.8e-33 114.4 1.0 5.2e-33 114.0 1.0 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase KinB_sensor PF16767.5 ORY76265.1 - 0.042 14.3 0.2 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB HALZ PF02183.18 ORY76265.1 - 0.045 14.0 3.4 0.29 11.4 0.2 2.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF5320 PF17253.2 ORY76265.1 - 0.078 14.1 2.0 7.2 7.8 0.3 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5320) AAA_lid_10 PF17872.1 ORY76265.1 - 0.088 12.9 2.1 0.14 12.3 2.1 1.5 1 0 0 1 1 1 0 AAA lid domain Cnn_1N PF07989.11 ORY76265.1 - 0.12 12.5 4.5 0.42 10.8 2.7 2.6 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 ORY76265.1 - 0.14 11.1 5.9 0.18 10.6 5.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SOGA PF11365.8 ORY76265.1 - 0.4 11.8 7.0 2.3 9.4 3.5 2.5 2 1 0 2 2 2 0 Protein SOGA FlxA PF14282.6 ORY76265.1 - 1.6 8.8 8.8 0.074 13.0 1.5 2.3 1 1 1 2 2 2 0 FlxA-like protein YabA PF06156.13 ORY76265.1 - 2.4 8.9 6.8 0.33 11.6 2.8 1.7 2 1 0 2 2 2 0 Initiation control protein YabA DivIVA PF05103.13 ORY76265.1 - 6 7.0 12.5 7.1 6.7 10.3 2.2 2 1 0 2 2 2 0 DivIVA protein ACT_7 PF13840.6 ORY76266.1 - 6.4e-20 70.7 0.2 7.7e-11 41.6 0.1 2.4 2 0 0 2 2 2 2 ACT domain SR-25 PF10500.9 ORY76266.1 - 0.0076 15.9 0.3 0.0076 15.9 0.3 4.9 4 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein ACT PF01842.25 ORY76266.1 - 0.076 12.8 0.6 6.5 6.6 0.1 2.7 2 0 0 2 2 2 0 ACT domain U3_snoRNA_assoc PF08297.11 ORY76266.1 - 2.7 8.7 6.5 1.8 9.3 0.2 2.8 2 0 0 2 2 2 0 U3 snoRNA associated peroxidase PF00141.23 ORY76267.1 - 3.6e-46 157.7 0.0 5.2e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 ORY76267.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Na_H_Exchanger PF00999.21 ORY76268.1 - 2.8e-59 200.8 32.2 3.5e-59 200.5 32.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ecl1 PF12855.7 ORY76269.1 - 0.018 16.2 30.7 0.018 16.2 30.7 2.6 1 1 1 2 2 2 0 ECL1/2/3 zinc binding proteins DUF3605 PF12239.8 ORY76270.1 - 8.1e-27 94.4 0.0 6.9e-15 55.7 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) PEPCK_ATP PF01293.20 ORY76272.1 - 6.8e-215 714.1 0.0 8.2e-215 713.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 ORY76272.1 - 0.046 13.9 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY76272.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arv1 PF04161.13 ORY76273.1 - 5.1e-27 95.4 0.7 7.4e-26 91.6 0.2 2.4 2 1 0 2 2 2 1 Arv1-like family PAP2 PF01569.21 ORY76273.1 - 6.8 6.5 8.2 0.67 9.7 2.5 2.1 2 1 0 2 2 2 0 PAP2 superfamily F-box-like PF12937.7 ORY76274.1 - 0.00082 19.2 2.9 0.0049 16.7 2.8 2.1 1 1 0 1 1 1 1 F-box-like Kelch_4 PF13418.6 ORY76275.1 - 8.3e-14 51.3 0.1 2e-05 24.5 0.0 3.8 3 1 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY76275.1 - 3.9e-11 42.9 3.1 0.00028 21.1 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY76275.1 - 4e-10 39.4 0.2 0.0022 18.0 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 ORY76275.1 - 7e-10 38.8 0.1 0.011 16.0 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 ORY76275.1 - 2.8e-08 33.2 0.0 0.01 15.4 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 ORY76275.1 - 2.9e-07 30.2 0.1 0.026 14.5 0.0 3.1 3 0 0 3 3 3 2 Kelch motif Kinesin PF00225.23 ORY76276.1 - 7e-95 317.7 0.0 1.2e-94 317.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY76276.1 - 7.3e-23 81.2 0.0 1.8e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding F-box-like PF12937.7 ORY76278.1 - 6.6e-07 29.1 1.6 1.3e-06 28.2 0.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY76278.1 - 0.0015 18.9 4.8 0.49 10.9 0.9 4.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY76278.1 - 2.5 8.1 9.3 0.26 11.2 2.3 3.0 2 1 0 2 2 2 0 F-box domain Cyclin_N PF00134.23 ORY76279.1 - 7.4e-38 129.2 0.2 1e-35 122.3 0.1 3.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY76279.1 - 1.4e-25 89.7 0.1 2.3e-25 89.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain FAM194 PF14977.6 ORY76282.1 - 0.082 12.2 0.2 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 FAM194 protein 4HB PF17947.1 ORY76282.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Four helical bundle domain PAP1 PF08601.10 ORY76282.1 - 4.2 7.0 14.9 4.4 6.9 14.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 ORY76282.1 - 4.7 5.6 10.1 5.3 5.5 10.1 1.0 1 0 0 1 1 1 0 Macoilin family Polyketide_cyc2 PF10604.9 ORY76283.1 - 0.00059 20.1 0.0 0.00068 19.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PKD PF00801.20 ORY76283.1 - 0.053 13.4 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 PKD domain LBR_tudor PF09465.10 ORY76283.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain APG6_N PF17675.1 ORY76284.1 - 0.00022 21.7 15.5 0.00022 21.7 15.5 22.4 4 4 15 20 20 20 3 Apg6 coiled-coil region Spc7 PF08317.11 ORY76284.1 - 0.00043 19.3 11.6 0.00043 19.3 11.6 17.6 3 3 15 19 19 19 10 Spc7 kinetochore protein ATG16 PF08614.11 ORY76284.1 - 0.0018 18.6 3.5 0.0018 18.6 3.5 19.1 3 3 14 17 17 17 6 Autophagy protein 16 (ATG16) Pox_A_type_inc PF04508.12 ORY76284.1 - 0.95 9.4 23.6 5.6 7.0 0.1 9.5 8 0 0 8 8 8 0 Viral A-type inclusion protein repeat RVT_N PF13655.6 ORY76285.1 - 0.03 14.6 0.3 0.053 13.8 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase F-box-like PF12937.7 ORY76286.1 - 2.6e-05 24.0 0.2 2.6e-05 24.0 0.2 1.8 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 ORY76287.1 - 3.8e-36 124.8 0.0 4.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY76287.1 - 6.4e-18 65.0 0.0 2.2e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY76287.1 - 0.00017 21.6 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY76287.1 - 0.0022 17.4 0.0 0.0042 16.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ORY76287.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 ORY76287.1 - 0.0066 16.1 0.0 0.032 13.8 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 ORY76287.1 - 0.012 14.9 0.0 0.047 13.0 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 ORY76287.1 - 0.057 12.2 0.0 0.069 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 ORY76287.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TPR_MLP1_2 PF07926.12 ORY76288.1 - 1e-31 109.6 20.1 1e-31 109.6 20.1 19.8 9 6 10 20 20 20 5 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 ORY76288.1 - 0.0022 18.0 16.4 0.0022 18.0 16.4 18.1 7 4 8 18 18 18 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 ORY76288.1 - 0.0041 17.6 0.6 0.0041 17.6 0.6 14.9 8 5 6 15 15 15 2 Protein of unknown function DUF16 KASH_CCD PF14662.6 ORY76288.1 - 0.0052 16.6 23.6 0.0052 16.6 23.6 14.9 6 5 6 14 14 14 1 Coiled-coil region of CCDC155 or KASH RVT_N PF13655.6 ORY76289.1 - 0.03 14.6 0.3 0.055 13.7 0.3 1.4 1 0 0 1 1 1 0 N-terminal domain of reverse transcriptase Sec1 PF00995.23 ORY76290.1 - 9.5e-128 427.9 0.0 1.2e-127 427.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family F-box-like PF12937.7 ORY76291.1 - 0.012 15.5 2.2 0.016 15.1 0.2 2.3 2 0 0 2 2 2 0 F-box-like DUF5335 PF17269.2 ORY76291.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Thymidylat_synt PF00303.19 ORY76292.1 - 1e-101 339.6 0.0 1.2e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase UL42 PF17638.2 ORY76292.1 - 4.5 7.3 8.0 1.6 8.7 5.3 1.6 2 0 0 2 2 2 0 HCMV UL42 COG6 PF06419.11 ORY76293.1 - 6.5e-159 530.1 0.0 8.2e-159 529.7 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 PI3K_P85_iSH2 PF16454.5 ORY76293.1 - 0.062 12.9 0.5 2.6 7.6 0.2 2.3 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ribosomal_S11 PF00411.19 ORY76294.1 - 1.5e-46 157.3 2.2 1.8e-46 157.0 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 ORY76294.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) DEAD PF00270.29 ORY76297.1 - 5.2e-48 163.1 0.0 1.7e-47 161.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY76297.1 - 2.2e-15 56.9 0.0 9.8e-13 48.4 0.0 3.0 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY76297.1 - 3.6e-08 33.6 0.0 8.2e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2443 PF10398.9 ORY76297.1 - 0.028 14.5 0.1 0.055 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_30 PF13604.6 ORY76297.1 - 0.038 13.7 0.0 0.17 11.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF2313 PF10076.9 ORY76297.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) UTP25 PF06862.12 ORY76297.1 - 0.12 11.1 0.0 12 4.6 0.0 2.6 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ank_4 PF13637.6 ORY76495.1 - 1.8e-10 41.2 4.4 5e-08 33.3 0.5 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY76495.1 - 1.8e-08 34.4 3.1 1.6e-06 28.3 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ORY76495.1 - 2e-08 34.7 0.1 2.5e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY76495.1 - 2.2e-08 33.7 1.7 4.7e-06 26.5 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY76495.1 - 1.3e-06 28.6 1.4 1.2e-05 25.5 1.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) adh_short_C2 PF13561.6 ORY76496.1 - 1.2e-54 185.3 0.1 1.5e-54 185.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY76496.1 - 6.4e-47 159.5 0.7 8.3e-47 159.2 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY76496.1 - 6.2e-15 55.6 0.3 8.6e-15 55.1 0.3 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ORY76496.1 - 0.0073 15.6 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 ORY76496.1 - 0.011 15.6 0.1 0.032 14.1 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 ORY76497.1 - 1.9e-16 59.9 46.8 1.9e-16 59.9 46.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily YpmT PF17431.2 ORY76497.1 - 1.1 9.4 3.1 28 4.9 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized YmpT-like RPEL PF02755.15 ORY76498.1 - 0.18 11.6 0.6 0.39 10.5 0.6 1.6 1 0 0 1 1 1 0 RPEL repeat GATase_6 PF13522.6 ORY76499.1 - 1.3e-07 31.9 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY76499.1 - 7.1e-07 28.4 0.6 0.00031 19.7 0.3 2.8 2 1 0 2 2 2 2 Glutamine amidotransferases class-II PLA2_B PF01735.18 ORY76500.1 - 2.1e-20 72.6 0.0 7e-20 70.9 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain FA_hydroxylase PF04116.13 ORY76500.1 - 0.47 10.8 2.5 1.2 9.5 2.5 1.6 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily MFS_2 PF13347.6 ORY76502.1 - 0.0002 20.1 0.6 0.0002 20.1 0.6 2.2 3 0 0 3 3 3 1 MFS/sugar transport protein Na_H_Exchanger PF00999.21 ORY76503.1 - 3.1e-71 240.2 39.6 3.1e-71 240.2 39.6 3.3 2 1 0 3 3 3 1 Sodium/hydrogen exchanger family MFS_1 PF07690.16 ORY76503.1 - 8.1e-38 130.2 54.6 8.1e-38 130.2 54.6 5.1 4 2 0 4 4 4 1 Major Facilitator Superfamily PDR_CDR PF06422.12 ORY76503.1 - 0.069 13.1 0.7 1.3 8.9 0.6 2.9 2 0 0 2 2 2 0 CDR ABC transporter PWWP PF00855.17 ORY76504.1 - 0.0018 18.7 0.0 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 PWWP domain MAGE_N PF12440.8 ORY76504.1 - 0.33 11.6 7.3 0.17 12.6 3.8 2.1 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Noc2 PF03715.13 ORY76505.1 - 9.6e-95 317.3 0.0 3e-49 167.9 0.0 2.3 1 1 1 2 2 2 2 Noc2p family Nop14 PF04147.12 ORY76505.1 - 0.12 10.6 0.0 0.12 10.6 0.0 2.2 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 ORY76505.1 - 3.3 6.9 25.5 5.9 6.1 25.5 1.3 1 0 0 1 1 1 0 BUD22 Thi4 PF01946.17 ORY76506.1 - 6.9e-103 342.9 0.0 8.8e-103 342.6 0.0 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORY76506.1 - 8.3e-07 29.2 0.2 2.3e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY76506.1 - 1.6e-06 28.0 2.1 2.8e-06 27.1 1.9 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY76506.1 - 4e-05 23.7 0.4 0.005 16.8 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY76506.1 - 4.6e-05 22.6 0.4 7e-05 22.0 0.4 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY76506.1 - 7.3e-05 22.1 0.1 0.00011 21.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY76506.1 - 0.00092 18.4 1.4 0.00092 18.4 1.4 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORY76506.1 - 0.0038 16.0 0.5 0.0056 15.4 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 ORY76506.1 - 0.042 13.1 0.2 0.069 12.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY76506.1 - 0.056 12.5 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY76506.1 - 0.057 12.7 0.3 0.057 12.7 0.3 1.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY76506.1 - 0.11 11.8 0.2 0.15 11.3 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase UIM PF02809.20 ORY76507.1 - 2.7 8.1 8.4 14 5.9 1.9 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Trypan_PARP PF05887.11 ORY76508.1 - 5.2 7.1 10.1 4.2 7.4 7.6 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) MFS_1 PF07690.16 ORY76509.1 - 2.6e-31 108.8 32.4 7.4e-31 107.3 32.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 ORY76509.1 - 6.6 7.0 20.4 45 4.4 1.3 5.0 2 1 3 5 5 5 0 Domain of unknown function (DUF1772) PWWP PF00855.17 ORY76510.1 - 2.7e-06 27.7 0.3 5.8e-06 26.6 0.3 1.6 1 0 0 1 1 1 1 PWWP domain 60KD_IMP PF02096.20 ORY76511.1 - 8.6e-27 94.1 6.4 1.5e-26 93.3 6.4 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein FSA_C PF10479.9 ORY76511.1 - 7.2 4.6 5.6 14 3.6 5.6 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus P16-Arc PF04699.14 ORY76512.1 - 1.8e-47 161.6 0.0 2e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 ORY76512.1 - 0.024 14.9 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Dip2/Utp12 Family FAP PF07174.11 ORY76513.1 - 2.1 7.7 17.4 2.4 7.6 17.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) VTC PF09359.10 ORY76515.1 - 0.03 13.7 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 VTC domain MT-A70 PF05063.14 ORY76516.1 - 2.5e-30 105.7 0.0 3.9e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 MT-A70 FGGY_N PF00370.21 ORY76517.1 - 4.1e-16 59.3 0.0 8e-13 48.5 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 ORY76517.1 - 6.2e-16 58.7 0.0 1.3e-14 54.4 0.0 2.5 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain UQ_con PF00179.26 ORY76518.1 - 6.6e-36 123.0 0.0 1.1e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MFS_1 PF07690.16 ORY76518.1 - 9.1e-30 103.8 48.0 2.2e-28 99.2 28.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily RWD PF05773.22 ORY76518.1 - 0.028 14.7 0.0 0.077 13.3 0.0 1.7 2 0 0 2 2 2 0 RWD domain Prok-E2_B PF14461.6 ORY76518.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B DIOX_N PF14226.6 ORY76519.1 - 2.3e-23 83.2 0.0 3.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY76519.1 - 5e-16 59.0 0.0 9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mur_ligase_M PF08245.12 ORY76520.1 - 6.2e-07 29.6 0.0 2e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain HLH PF00010.26 ORY76521.1 - 1.6e-15 56.8 1.0 3.9e-15 55.5 1.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain REV1_C PF16727.5 ORY76521.1 - 0.0087 16.4 1.8 0.014 15.7 1.8 1.4 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain EcoR124_C PF12008.8 ORY76521.1 - 0.034 13.8 1.0 0.037 13.7 1.0 1.1 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal FlaC_arch PF05377.11 ORY76521.1 - 0.098 13.1 1.0 0.32 11.4 0.2 2.1 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 ORY76521.1 - 0.13 11.1 4.5 0.15 10.9 4.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein LCE6A PF15858.5 ORY76522.1 - 5 7.9 7.5 2.9 8.7 5.6 1.6 1 1 0 1 1 1 0 Late cornified envelope protein 6A family PWWP PF00855.17 ORY76523.1 - 1.8e-09 37.9 0.9 3.1e-09 37.1 0.9 1.4 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 ORY76523.1 - 0.0017 18.2 9.0 0.0096 15.8 9.0 2.0 1 1 0 1 1 1 1 PHD-finger Zn_Tnp_IS91 PF14319.6 ORY76523.1 - 0.023 14.7 1.5 0.041 13.9 1.5 1.4 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF3220 PF11516.8 ORY76523.1 - 0.061 13.5 0.1 0.4 10.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3120) SRF-TF PF00319.18 ORY76527.1 - 7.5e-21 73.4 0.2 1.4e-20 72.5 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1631 PF07793.11 ORY76528.1 - 0.087 11.2 1.9 0.11 10.9 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) IQCJ-SCHIP1 PF15157.6 ORY76528.1 - 1.7 8.5 4.0 2.9 7.7 4.0 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif PVL_ORF50 PF07768.11 ORY76530.1 - 0.016 15.5 3.0 0.018 15.4 3.0 1.1 1 0 0 1 1 1 0 PVL ORF-50-like family Pantoate_ligase PF02569.15 ORY76531.1 - 2.7e-86 289.1 0.0 3.4e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Caleosin PF05042.13 ORY76532.1 - 6.7e-72 240.9 0.1 8.4e-72 240.6 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 ORY76532.1 - 0.0031 17.3 1.0 0.023 14.6 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 ORY76532.1 - 0.012 15.1 0.0 0.061 12.9 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 ORY76532.1 - 0.028 14.3 0.0 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair MFS_1 PF07690.16 ORY76533.1 - 1.1e-42 146.3 34.8 1.1e-42 146.3 34.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY76533.1 - 3.4e-09 36.1 25.6 3.5e-08 32.8 25.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORY76533.1 - 1.1e-05 24.1 2.0 1.8e-05 23.4 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cupin_8 PF13621.6 ORY76534.1 - 6.7e-19 68.6 0.0 9.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Peptidase_C14 PF00656.22 ORY76536.1 - 2.1e-56 191.7 0.1 3.2e-56 191.0 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 ORY76536.1 - 0.07 13.1 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain DUF2613 PF11021.8 ORY76537.1 - 0.0084 16.2 2.2 0.018 15.1 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2613) HhH-GPD PF00730.25 ORY76538.1 - 8.7e-08 32.6 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TIMELESS_C PF05029.13 ORY76538.1 - 0.047 12.8 2.0 0.068 12.3 2.0 1.1 1 0 0 1 1 1 0 Timeless protein C terminal region SNF2_N PF00176.23 ORY76539.1 - 7.3e-42 143.3 0.0 3e-41 141.3 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Prok-RING_4 PF14447.6 ORY76539.1 - 9.4e-11 41.4 4.3 1.7e-10 40.6 4.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY76539.1 - 1.4e-10 40.9 6.1 2.5e-10 40.1 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY76539.1 - 1.5e-08 34.3 6.7 2.8e-08 33.5 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY76539.1 - 2.1e-08 33.9 7.0 4.3e-08 32.9 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY76539.1 - 4.1e-08 33.4 7.8 8.5e-08 32.4 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY76539.1 - 2.5e-07 30.5 7.1 4.7e-07 29.7 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 ORY76539.1 - 1.3e-05 25.5 0.0 9.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 ORY76539.1 - 0.0003 20.8 3.6 0.00061 19.8 3.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY76539.1 - 0.00033 20.9 4.0 0.00074 19.8 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORY76539.1 - 0.025 14.8 7.0 0.048 13.8 7.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY76539.1 - 0.19 11.6 5.6 0.4 10.5 5.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0524 PF15823.5 ORY76539.1 - 0.31 10.4 2.2 1.8 7.9 0.7 2.3 2 0 0 2 2 2 0 UPF0524 of C3orf70 zf-P11 PF03854.14 ORY76539.1 - 1.6 8.4 8.7 0.21 11.2 3.6 2.1 2 0 0 2 2 2 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 ORY76539.1 - 9 6.0 7.0 17 5.1 7.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type HMMR_N PF15905.5 ORY76540.1 - 0.0062 16.0 16.5 0.0062 16.0 16.5 2.2 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal ABC_tran_CTD PF16326.5 ORY76540.1 - 0.012 15.8 12.0 0.012 15.8 12.0 4.0 1 1 3 4 4 4 0 ABC transporter C-terminal domain DUF812 PF05667.11 ORY76540.1 - 0.013 14.4 25.6 0.13 11.1 16.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ADIP PF11559.8 ORY76540.1 - 0.066 13.3 26.4 0.55 10.3 7.2 3.5 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4349 PF14257.6 ORY76540.1 - 0.36 10.3 25.1 1.5 8.3 0.4 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4349) HIP1_clath_bdg PF16515.5 ORY76540.1 - 0.42 11.3 24.5 2 9.1 0.9 3.5 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 ORY76540.1 - 0.46 10.9 26.7 0.47 10.9 23.4 2.3 1 1 1 2 2 2 0 Fez1 Golgin_A5 PF09787.9 ORY76540.1 - 0.55 9.6 33.0 0.091 12.2 17.7 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 ORY76540.1 - 0.69 9.2 27.3 0.036 13.4 12.3 2.6 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ORY76540.1 - 0.83 8.5 33.8 4.2 6.2 6.8 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF2730 PF10805.8 ORY76540.1 - 0.85 9.8 12.9 2.3 8.4 3.8 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 ORY76540.1 - 1.7 8.0 25.5 17 4.7 4.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.7 ORY76540.1 - 1.8 8.7 33.1 0.081 13.1 20.1 2.2 1 1 1 2 2 2 0 Tropomyosin like DUF724 PF05266.14 ORY76540.1 - 2.3 8.0 28.4 0.21 11.4 7.8 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 ORY76540.1 - 2.7 8.1 14.9 6.7 6.8 3.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) V-SNARE PF05008.15 ORY76540.1 - 2.8 8.4 18.3 1.1 9.7 2.8 3.5 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus FliD_N PF02465.18 ORY76540.1 - 3 8.6 8.8 12 6.7 1.1 3.1 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ATG16 PF08614.11 ORY76540.1 - 3.1 8.0 36.5 7.1 6.8 9.7 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 ORY76540.1 - 3.6 7.8 14.4 5.4 7.2 6.5 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF5082 PF16888.5 ORY76540.1 - 3.7 7.9 24.4 1.4 9.2 10.7 3.5 2 1 2 4 4 3 0 Domain of unknown function (DUF5082) DHR10 PF18595.1 ORY76540.1 - 4.9 7.3 37.8 4.5 7.3 13.2 3.5 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain COG2 PF06148.11 ORY76540.1 - 5.1 7.2 17.8 3.7 7.6 0.9 3.5 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIC PF04977.15 ORY76540.1 - 5.2 6.9 29.7 2.8 7.8 2.1 4.9 3 1 2 5 5 5 0 Septum formation initiator HOOK PF05622.12 ORY76540.1 - 5.3 5.1 32.1 0.28 9.3 5.5 2.5 2 1 1 3 3 3 0 HOOK protein RasGAP_C PF03836.15 ORY76540.1 - 5.3 7.2 15.5 1.2 9.3 3.0 3.7 2 2 2 5 5 4 0 RasGAP C-terminus DUF16 PF01519.16 ORY76540.1 - 5.3 7.6 21.7 2.7 8.5 3.2 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 YgaB PF14182.6 ORY76540.1 - 7.6 7.0 21.1 13 6.3 4.8 3.9 2 1 1 3 3 3 0 YgaB-like protein BLOC1_2 PF10046.9 ORY76540.1 - 7.8 6.9 16.3 2.1 8.7 3.0 3.5 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Seryl_tRNA_N PF02403.22 ORY76540.1 - 9.6 6.5 29.1 2 8.7 8.8 3.5 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain USP8_interact PF08941.10 ORY76540.1 - 9.9 5.9 9.5 16 5.2 0.4 3.1 2 1 2 4 4 4 0 USP8 interacting Na_Ca_ex PF01699.24 ORY76541.1 - 1.2e-38 132.5 38.4 8.1e-20 71.3 15.6 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.6 ORY76541.1 - 0.066 13.5 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 YWFCY protein DUF3169 PF11368.8 ORY76541.1 - 2.2 7.7 8.7 0.29 10.6 0.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF3169) PH_3 PF14593.6 ORY76542.1 - 4.1e-08 33.3 0.0 6.5e-08 32.6 0.0 1.4 1 1 0 1 1 1 1 PH domain Pkinase PF00069.25 ORY76543.1 - 1.3e-60 205.0 0.0 1.6e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY76543.1 - 3.7e-33 114.9 0.0 4.1e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY76543.1 - 8.8e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY76543.1 - 1.4e-06 27.8 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY76543.1 - 2e-06 27.0 0.0 2.5e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY76543.1 - 0.00033 20.6 0.0 0.00096 19.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY76543.1 - 0.0087 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORY76543.1 - 0.034 13.8 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 ORY76543.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Seadorna_VP7 PF07387.11 ORY76543.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 vWA-TerF-like PF10138.9 ORY76545.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus DEDD_Tnp_IS110 PF01548.17 ORY76546.1 - 0.001 18.9 0.2 0.0015 18.5 0.2 1.2 1 0 0 1 1 1 1 Transposase ATG16 PF08614.11 ORY76548.1 - 0.0045 17.2 43.9 0.21 11.8 26.8 3.6 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) HOOK PF05622.12 ORY76548.1 - 0.0048 15.1 26.6 0.069 11.3 0.6 2.6 3 0 0 3 3 3 2 HOOK protein Fez1 PF06818.15 ORY76548.1 - 0.008 16.7 30.1 0.048 14.1 28.3 2.5 1 1 0 1 1 1 1 Fez1 FliJ PF02050.16 ORY76548.1 - 0.18 12.1 0.3 0.18 12.1 0.3 3.4 3 1 1 4 4 3 0 Flagellar FliJ protein SANTA PF09133.10 ORY76548.1 - 0.18 12.3 0.1 3.5 8.2 0.0 2.7 3 0 0 3 3 2 0 SANTA (SANT Associated) Bcr-Abl_Oligo PF09036.10 ORY76548.1 - 0.19 11.8 18.6 0.32 11.0 1.6 4.3 4 1 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain KxDL PF10241.9 ORY76548.1 - 0.19 12.0 17.9 1.6 9.0 0.4 4.9 5 0 0 5 5 5 0 Uncharacterized conserved protein PilJ PF13675.6 ORY76548.1 - 0.2 11.7 12.6 0.061 13.4 4.4 2.8 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4407 PF14362.6 ORY76548.1 - 0.34 10.2 27.1 2 7.7 27.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 ORY76548.1 - 0.35 11.3 40.5 0.93 9.9 3.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) PLAC9 PF15205.6 ORY76548.1 - 0.52 10.7 0.0 0.52 10.7 0.0 3.0 3 1 1 4 4 3 0 Placenta-specific protein 9 DUF3138 PF11336.8 ORY76548.1 - 0.87 8.1 7.5 0.095 11.3 2.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Fib_alpha PF08702.10 ORY76548.1 - 0.97 9.6 21.1 10 6.3 1.2 4.1 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.21 ORY76548.1 - 1.5 8.4 34.6 0.46 10.0 1.6 3.6 3 1 2 5 5 5 0 Intermediate filament protein Spc7 PF08317.11 ORY76548.1 - 1.9 7.3 39.5 0.87 8.4 5.6 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 ORY76548.1 - 3.1 8.4 33.4 4 8.1 1.6 3.5 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HR1 PF02185.16 ORY76548.1 - 4.2 7.6 37.4 3.8 7.7 2.6 5.6 3 1 2 5 5 5 0 Hr1 repeat DUF4349 PF14257.6 ORY76548.1 - 4.5 6.7 29.3 0.93 8.9 4.8 3.9 1 1 1 2 2 1 0 Domain of unknown function (DUF4349) V_ATPase_I PF01496.19 ORY76548.1 - 4.8 5.0 21.1 0.34 8.8 0.4 2.4 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family ABC_tran_CTD PF16326.5 ORY76548.1 - 6.2 7.1 46.6 0.48 10.7 13.9 4.3 2 1 2 4 4 3 0 ABC transporter C-terminal domain Allexi_40kDa PF05549.11 ORY76548.1 - 7.3 6.0 12.1 5.4 6.5 1.7 2.7 1 1 2 3 3 3 0 Allexivirus 40kDa protein FapA PF03961.13 ORY76548.1 - 8.2 4.9 25.4 5.9 5.4 8.2 2.5 1 1 2 3 3 3 0 Flagellar Assembly Protein A FPP PF05911.11 ORY76548.1 - 9.4 4.3 34.1 1.7 6.7 2.9 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil sCache_3_2 PF17203.4 ORY76551.1 - 0.42 10.7 3.5 6.6 6.9 0.0 3.0 3 0 0 3 3 3 0 Single cache domain 3 HSP70 PF00012.20 ORY76554.1 - 0.061 11.5 0.1 0.27 9.3 0.0 1.8 2 0 0 2 2 2 0 Hsp70 protein MARVEL PF01284.23 ORY76555.1 - 0.0032 17.5 8.6 0.0067 16.5 8.3 1.7 1 1 0 1 1 1 1 Membrane-associating domain PAP1 PF08601.10 ORY76555.1 - 0.2 11.4 3.5 0.35 10.6 3.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 GCP_N_terminal PF17681.1 ORY76556.1 - 0.045 13.4 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal DivIC PF04977.15 ORY76556.1 - 0.051 13.3 0.8 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 ORY76556.1 - 0.16 12.6 8.1 1.8 9.3 0.1 4.2 3 1 0 4 4 4 0 SlyX Tmemb_cc2 PF10267.9 ORY76556.1 - 0.3 10.2 3.0 0.66 9.0 0.3 2.1 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Cortex-I_coil PF09304.10 ORY76556.1 - 0.48 10.7 8.5 0.076 13.2 4.0 2.0 3 0 0 3 3 3 0 Cortexillin I, coiled coil Fez1 PF06818.15 ORY76556.1 - 0.85 10.0 9.0 0.93 9.9 6.3 2.5 2 1 0 2 2 2 0 Fez1 COG5 PF10392.9 ORY76556.1 - 1.1 9.5 3.9 0.64 10.2 0.3 2.4 3 0 0 3 3 3 0 Golgi transport complex subunit 5 TPR_MLP1_2 PF07926.12 ORY76556.1 - 4.1 7.5 11.5 2.9 8.0 2.0 3.4 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 ORY76558.1 - 0.089 12.9 16.1 0.71 9.9 9.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Ead_Ea22 PF13935.6 ORY76558.1 - 0.14 12.8 14.4 1.4 9.5 5.4 2.1 1 1 1 2 2 2 0 Ead/Ea22-like protein FapA PF03961.13 ORY76558.1 - 0.19 10.3 8.5 0.33 9.5 8.5 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A End3 PF12761.7 ORY76558.1 - 0.21 11.7 12.6 0.31 11.2 12.6 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 ABC_tran_CTD PF16326.5 ORY76558.1 - 0.28 11.4 29.3 0.063 13.5 14.6 2.8 1 1 2 3 3 3 0 ABC transporter C-terminal domain CASP_C PF08172.12 ORY76558.1 - 0.42 9.9 11.2 1.3 8.3 0.3 2.5 1 1 0 2 2 2 0 CASP C terminal V_ATPase_I PF01496.19 ORY76558.1 - 0.52 8.2 5.7 0.59 8.0 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KxDL PF10241.9 ORY76558.1 - 0.6 10.4 5.4 6.4 7.1 0.6 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF737 PF05300.11 ORY76558.1 - 0.89 9.9 19.7 1.4 9.2 19.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF1664 PF07889.12 ORY76558.1 - 1 9.4 7.1 12 6.0 6.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med9 PF07544.13 ORY76558.1 - 1.1 9.4 14.3 5.3 7.2 3.8 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF812 PF05667.11 ORY76558.1 - 1.1 8.1 16.9 1.4 7.7 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 ORY76558.1 - 1.2 7.9 21.4 4.1 6.2 11.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ERM PF00769.19 ORY76558.1 - 1.3 8.8 23.0 1.9 8.2 23.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2730 PF10805.8 ORY76558.1 - 1.5 8.9 9.9 1.5 8.9 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.9 ORY76558.1 - 1.8 8.9 11.4 1.3 9.3 4.5 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 ORY76558.1 - 2.2 8.1 17.5 10 5.9 5.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) YgaB PF14182.6 ORY76558.1 - 3.9 7.9 15.0 32 5.0 2.3 2.9 1 1 1 2 2 2 0 YgaB-like protein FAM76 PF16046.5 ORY76558.1 - 4 6.7 8.7 5.3 6.3 8.7 1.2 1 0 0 1 1 1 0 FAM76 protein DUF5082 PF16888.5 ORY76558.1 - 4.4 7.6 11.8 2 8.7 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Phlebovirus_NSM PF07246.11 ORY76558.1 - 5.9 6.2 8.5 7.9 5.8 8.5 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M PEARLI-4 PF05278.12 ORY76558.1 - 6.4 6.3 16.1 8.5 5.9 15.4 1.5 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Spc24 PF08286.11 ORY76558.1 - 8.9 6.6 16.2 31 4.9 4.9 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 ORY76558.1 - 9 6.4 15.7 19 5.3 15.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Bcr-Abl_Oligo PF09036.10 ORY76558.1 - 9.2 6.3 7.6 19 5.3 1.5 2.5 1 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain ATG16 PF08614.11 ORY76559.1 - 0.39 10.9 25.5 1.2 9.3 3.0 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 ORY76559.1 - 2.9 8.2 9.7 1.5 9.1 1.8 3.5 3 1 0 3 3 3 0 ABC transporter C-terminal domain GAS PF13851.6 ORY76559.1 - 7 5.9 15.9 0.97 8.7 6.3 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CD20 PF04103.15 ORY76560.1 - 0.0055 16.8 1.1 1.5 8.9 0.0 3.0 3 0 0 3 3 3 1 CD20-like family YrhK PF14145.6 ORY76560.1 - 0.42 10.5 0.1 0.42 10.5 0.1 4.1 4 1 1 5 5 5 0 YrhK-like protein DUF4131 PF13567.6 ORY76560.1 - 0.53 9.9 9.2 0.65 9.6 0.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) 2OG-FeII_Oxy_2 PF13532.6 ORY76561.1 - 1.4e-11 44.9 0.0 2.3e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DPBB_1 PF03330.18 ORY76562.1 - 5e-06 26.7 0.1 3.3e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY76562.1 - 0.0041 16.9 0.7 0.0049 16.7 0.7 1.2 1 0 0 1 1 1 1 Barwin family CARDB PF07705.11 ORY76562.1 - 0.02 15.2 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 CARDB DnaJ_CXXCXGXG PF00684.19 ORY76562.1 - 0.03 14.7 1.0 0.044 14.2 1.0 1.4 1 1 0 1 1 1 0 DnaJ central domain zinc_ribbon_2 PF13240.6 ORY76562.1 - 0.24 11.2 3.9 2 8.2 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DUF4330 PF14221.6 ORY76564.1 - 0.096 12.9 0.4 0.2 11.9 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4330) Podoplanin PF05808.11 ORY76564.1 - 0.27 11.3 5.6 0.12 12.4 2.9 1.8 2 0 0 2 2 2 0 Podoplanin PWWP PF00855.17 ORY76565.1 - 0.00016 22.0 0.0 0.00033 21.0 0.0 1.6 1 0 0 1 1 1 1 PWWP domain PHD PF00628.29 ORY76566.1 - 5.5e-05 23.0 3.0 7.2e-05 22.6 3.0 1.2 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY76566.1 - 0.0032 17.0 3.2 0.0043 16.6 3.2 1.2 1 0 0 1 1 1 1 PHD-finger adh_short_C2 PF13561.6 ORY76567.1 - 5.1e-36 124.4 0.0 9e-35 120.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY76567.1 - 1.2e-31 109.8 0.3 1.9e-31 109.1 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY76567.1 - 0.00059 19.8 0.4 0.00059 19.8 0.4 1.6 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.19 ORY76568.1 - 1.5e-13 50.4 0.0 2.4e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY76568.1 - 6.5e-13 48.7 0.0 9.1e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY76568.1 - 4.9e-10 39.0 0.1 3.3e-09 36.3 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ORY76568.1 - 3.8e-07 30.2 0.1 2.1e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY76568.1 - 4.5e-07 29.6 0.2 0.00033 20.2 0.2 2.7 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY76568.1 - 1.1e-05 25.1 0.0 0.00023 20.8 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY76568.1 - 0.0025 17.0 0.0 0.024 13.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY76568.1 - 0.037 13.9 0.2 0.25 11.2 0.2 2.1 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 ORY76568.1 - 0.15 11.5 0.1 0.35 10.3 0.1 1.7 1 1 0 1 1 1 0 short chain dehydrogenase G-alpha PF00503.20 ORY76569.1 - 6.5e-100 334.7 0.1 8e-100 334.4 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY76569.1 - 3.1e-14 52.8 0.2 1.9e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY76569.1 - 0.0018 17.7 2.2 0.069 12.5 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY76569.1 - 0.0031 17.1 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 ORY76569.1 - 0.013 15.7 0.4 5.8 7.1 0.0 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ORY76569.1 - 0.015 14.7 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ORY76569.1 - 0.061 13.4 0.0 3.9 7.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY76569.1 - 0.079 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIN_9 PF18477.1 ORY76569.1 - 0.088 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 PIN like domain DUF202 PF02656.15 ORY76571.1 - 8e-06 26.2 1.6 3.6e-05 24.1 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4381 PF14316.6 ORY76572.1 - 0.034 14.4 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Tad PF13400.6 ORY76572.1 - 0.098 13.0 2.7 0.25 11.7 2.7 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF4611 PF15387.6 ORY76574.1 - 0.022 15.0 6.5 1.9 8.7 5.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) E7 PF00527.18 ORY76574.1 - 0.093 12.9 1.4 0.19 12.0 1.4 1.4 1 0 0 1 1 1 0 E7 protein, Early protein PBP1_TM PF14812.6 ORY76574.1 - 0.14 12.5 0.8 0.28 11.6 0.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 ORY76574.1 - 0.17 11.6 5.6 0.27 10.9 5.6 1.2 1 0 0 1 1 1 0 FAM176 family CDH1_2_SANT_HL1 PF18375.1 ORY76574.1 - 0.27 11.9 2.9 0.62 10.8 2.9 1.5 1 0 0 1 1 1 0 CDH1/2 SANT-Helical linker 1 Methyltransf_15 PF09445.10 ORY76575.1 - 0.22 11.1 0.2 0.53 9.8 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Exo_endo_phos PF03372.23 ORY76576.1 - 6.4e-09 35.7 1.0 1.9e-08 34.2 1.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family G-alpha PF00503.20 ORY76577.1 - 1.7e-104 349.8 0.1 2.2e-104 349.4 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY76577.1 - 9.9e-15 54.4 0.6 3.7e-10 39.5 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY76577.1 - 0.00099 18.5 0.1 0.043 13.2 0.0 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY76577.1 - 0.0041 17.3 0.3 4 7.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY76577.1 - 0.0081 16.2 0.0 5.3 7.2 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY76577.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY76577.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 ORY76577.1 - 0.12 11.9 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF630 PF04783.12 ORY76577.1 - 0.15 12.3 0.7 1.4 9.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF630) G-alpha PF00503.20 ORY76578.1 - 1.8e-96 323.4 0.0 2.7e-96 322.8 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY76578.1 - 1.2e-12 47.7 0.3 1.8e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 ORY76578.1 - 0.025 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 ORY76578.1 - 0.026 14.6 0.1 3.3 7.8 0.1 2.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY76578.1 - 0.03 14.1 0.4 0.2 11.4 0.0 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain Roc PF08477.13 ORY76578.1 - 0.033 14.4 0.2 5.8 7.2 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY76578.1 - 0.06 12.7 1.7 0.43 9.9 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region COesterase PF00135.28 ORY76580.1 - 4e-06 26.0 0.0 0.00013 21.0 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY76580.1 - 6.1e-06 26.3 0.1 9.8e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY76580.1 - 0.007 15.9 0.0 0.027 14.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Syntaxin PF00804.25 ORY76582.1 - 5.5e-21 75.2 0.5 1.6e-20 73.6 0.5 1.7 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY76582.1 - 9.5e-05 22.3 0.5 0.00029 20.8 0.5 1.8 1 0 0 1 1 1 1 SNARE domain ODV-E18 PF10717.9 ORY76582.1 - 0.0016 18.3 1.3 0.041 13.7 0.1 2.3 2 0 0 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF1664 PF07889.12 ORY76582.1 - 0.0024 17.9 0.9 2.3 8.3 0.0 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.6 ORY76582.1 - 0.041 14.2 1.9 0.28 11.6 0.1 2.4 2 1 1 3 3 3 0 Syntaxin-like protein DUF3357 PF11837.8 ORY76582.1 - 0.088 13.3 2.4 0.24 11.9 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) OAD_gamma PF04277.13 ORY76582.1 - 8.8 7.0 9.7 1.3 9.7 5.5 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Adeno_PV PF03910.13 ORY76582.1 - 9 4.9 10.5 5.4 5.6 8.0 1.7 2 0 0 2 2 2 0 Adenovirus minor core protein PV DUF3431 PF11913.8 ORY76583.1 - 6.3e-05 22.9 0.0 0.0089 15.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) MDMPI_N PF11716.8 ORY76584.1 - 0.047 14.4 6.2 0.076 13.7 6.2 1.3 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain adh_short PF00106.25 ORY76846.1 - 6e-34 117.2 0.0 8.1e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY76846.1 - 2.6e-24 86.1 0.0 2.9e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY76846.1 - 5.3e-09 36.2 0.0 7.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY76846.1 - 0.00011 22.2 0.0 0.00012 22.1 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY76846.1 - 0.0037 16.5 0.1 0.037 13.2 0.0 2.3 2 1 1 3 3 3 1 Male sterility protein MCM PF00493.23 ORY76848.1 - 3.7e-104 346.7 0.0 6e-104 346.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY76848.1 - 1.4e-34 118.7 0.0 2.8e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY76848.1 - 2.3e-29 101.6 2.0 5.3e-29 100.5 2.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY76848.1 - 5.9e-14 52.5 0.1 1.7e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY76848.1 - 1.2e-06 28.0 0.0 0.0006 19.3 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY76848.1 - 3e-05 24.1 0.0 7.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY76848.1 - 0.00049 20.0 0.1 0.0026 17.6 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 ORY76848.1 - 0.018 15.6 1.8 0.018 15.6 1.8 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Sigma54_activat PF00158.26 ORY76848.1 - 0.048 13.4 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain PCI PF01399.27 ORY76849.1 - 5.4e-09 36.5 0.0 3.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 ORY76849.1 - 0.0046 16.7 0.1 0.011 15.5 0.1 1.6 1 1 0 1 1 1 1 26S proteasome subunit RPN7 DUF1682 PF07946.14 ORY76850.1 - 4.6e-47 160.8 0.0 5.6e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) F-box-like PF12937.7 ORY76851.1 - 0.0025 17.7 0.5 0.0025 17.7 0.5 2.4 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.18 ORY76852.1 - 1.9e-08 34.2 18.3 2.9e-08 33.7 18.3 1.3 1 0 0 1 1 1 1 MYND finger AMP-binding PF00501.28 ORY76853.1 - 5.9e-72 242.6 0.0 8.9e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY76853.1 - 1.1e-09 39.1 0.3 3.3e-09 37.6 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SepF PF04472.12 ORY76853.1 - 0.12 12.6 0.0 3.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Cell division protein SepF bZIP_1 PF00170.21 ORY76854.1 - 5.8e-09 35.9 14.5 9.3e-09 35.3 6.5 2.8 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY76854.1 - 1.8e-08 34.3 17.4 4.8e-08 33.0 7.0 2.9 2 1 1 3 3 3 2 Basic region leucine zipper Csm1_N PF18504.1 ORY76854.1 - 0.002 18.4 1.9 0.022 15.1 0.4 2.5 2 0 0 2 2 2 1 Csm1 N-terminal domain Rootletin PF15035.6 ORY76854.1 - 0.0032 17.5 4.4 0.01 15.9 4.0 1.9 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion JIP_LZII PF16471.5 ORY76854.1 - 0.017 15.3 2.1 0.017 15.3 2.1 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 ORY76854.1 - 0.062 13.6 0.9 0.062 13.6 0.9 2.1 2 1 0 2 2 2 0 TSC-22/dip/bun family BBP1_C PF15272.6 ORY76854.1 - 0.14 12.0 1.6 0.27 11.0 1.1 1.7 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal MCM3AP_GANP PF16769.5 ORY76854.1 - 0.43 8.8 3.6 0.59 8.3 3.6 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Macoilin PF09726.9 ORY76854.1 - 0.45 9.0 14.0 0.71 8.4 14.0 1.2 1 0 0 1 1 1 0 Macoilin family bZIP_Maf PF03131.17 ORY76854.1 - 0.65 10.6 16.7 0.1 13.1 3.7 2.8 3 0 0 3 3 3 0 bZIP Maf transcription factor Jnk-SapK_ap_N PF09744.9 ORY76854.1 - 1 9.6 8.5 0.092 13.0 0.7 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CDK2AP PF09806.9 ORY76854.1 - 1.4 8.9 17.1 0.7 9.9 15.1 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PI3K_1B_p101 PF10486.9 ORY76854.1 - 1.5 6.5 10.5 1.9 6.2 10.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ADIP PF11559.8 ORY76854.1 - 5.7 7.0 11.2 3.4 7.7 1.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding IATP PF04568.12 ORY76854.1 - 7 7.2 10.5 0.65 10.5 5.4 1.9 2 0 0 2 2 1 0 Mitochondrial ATPase inhibitor, IATP CDC45 PF02724.14 ORY76854.1 - 8.3 4.6 8.6 12 4.1 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein U3_assoc_6 PF08640.11 ORY76857.1 - 5.8e-28 96.8 1.0 4.4e-27 94.0 1.3 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_1 PF00515.28 ORY76858.1 - 1.6e-18 65.7 0.9 1.2e-05 24.9 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY76858.1 - 3.7e-16 57.9 10.3 0.00023 21.1 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY76858.1 - 4.7e-12 45.1 0.4 0.0061 16.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY76858.1 - 8e-12 44.6 0.1 0.00029 20.4 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 ORY76858.1 - 1.3e-11 44.2 10.4 0.00036 21.1 0.1 5.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY76858.1 - 1.2e-09 38.7 4.6 5.6e-08 33.3 0.3 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY76858.1 - 1.4e-08 34.5 0.2 0.039 14.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY76858.1 - 1e-07 31.5 3.0 0.21 11.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY76858.1 - 3.2e-06 27.4 9.6 1.2 9.4 0.0 5.0 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY76858.1 - 1.1e-05 25.8 0.1 0.51 10.9 0.0 3.7 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY76858.1 - 5.2e-05 23.3 3.5 0.0043 17.2 0.3 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY76858.1 - 9e-05 22.9 0.2 4.1 8.3 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY76858.1 - 0.0023 18.1 0.9 0.057 13.7 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 ORY76858.1 - 0.081 13.3 0.0 1.9 8.9 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF1641 PF07849.11 ORY76858.1 - 0.11 12.4 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) DUF2315 PF10231.9 ORY76858.1 - 0.19 11.8 0.8 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Apoptogenic protein 1 TPR_10 PF13374.6 ORY76858.1 - 0.47 10.4 2.8 26 4.8 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS18 PF17352.2 ORY76858.1 - 1.5 9.3 14.4 26 5.3 11.3 2.9 3 0 0 3 3 3 0 Male Flower Specific protein 18 AA_permease PF00324.21 ORY76859.1 - 5.7e-124 414.3 43.5 7e-124 414.0 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY76859.1 - 6.8e-30 104.2 45.8 1.1e-29 103.6 45.8 1.3 1 1 0 1 1 1 1 Amino acid permease YwiC PF14256.6 ORY76859.1 - 0.0062 16.8 2.5 0.0062 16.8 2.5 3.9 3 1 1 4 4 4 1 YwiC-like protein 4HBT_2 PF13279.6 ORY76860.1 - 3.9e-08 33.8 0.0 5.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily AMP-binding PF00501.28 ORY76862.1 - 4.5e-32 111.2 0.0 6e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY76862.1 - 6.7e-10 39.8 0.1 1.2e-09 39.0 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2674 PF10879.8 ORY76862.1 - 0.13 11.8 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2674) UPF0242 PF06785.11 ORY76863.1 - 0.011 15.9 3.0 0.014 15.5 3.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Spc24 PF08286.11 ORY76863.1 - 0.012 15.8 0.5 0.04 14.2 0.6 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 5_nucleotid PF05761.14 ORY76863.1 - 0.58 9.0 1.7 0.76 8.6 1.7 1.1 1 0 0 1 1 1 0 5' nucleotidase family DivIC PF04977.15 ORY76863.1 - 0.77 9.6 3.7 1.6 8.5 1.7 2.1 1 1 1 2 2 2 0 Septum formation initiator rhaM PF05336.13 ORY76864.1 - 1.4e-32 111.9 0.3 1.6e-32 111.8 0.3 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase adh_short_C2 PF13561.6 ORY76865.1 - 6.3e-60 202.6 0.1 1.4e-59 201.5 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY76865.1 - 9.6e-44 149.2 0.2 1.5e-43 148.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY76865.1 - 1.1e-09 38.4 0.2 1.7e-09 37.8 0.2 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ORY76865.1 - 0.045 13.1 0.1 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PEP_hydrolase PF09370.10 ORY76865.1 - 0.06 12.6 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like PRIMA1 PF16101.5 ORY76866.1 - 0.022 14.8 1.0 0.022 14.8 1.0 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 zf-RRN7 PF11781.8 ORY76866.1 - 0.075 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CAP_N PF01213.19 ORY76866.1 - 1.8 7.9 7.3 4.3 6.7 7.3 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Septin PF00735.18 ORY76867.1 - 1.4e-35 123.0 0.0 3.4e-13 49.5 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 ORY76867.1 - 0.011 15.8 0.6 0.028 14.5 0.6 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF815 PF05673.13 ORY76867.1 - 0.014 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 ORY76867.1 - 0.017 15.5 0.1 0.038 14.4 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY76867.1 - 0.024 14.0 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 ORY76867.1 - 0.055 13.0 0.1 0.093 12.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DLIC PF05783.11 ORY76867.1 - 0.13 11.1 0.4 0.29 9.9 0.1 1.8 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 ORY76867.1 - 0.28 11.4 2.4 0.21 11.7 0.4 1.8 2 0 0 2 2 2 0 AAA domain HATPase_c PF02518.26 ORY76868.1 - 1.2e-21 77.3 0.1 2.4e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY76868.1 - 3.1e-10 40.2 0.0 7.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY76868.1 - 6.3e-10 38.9 0.1 1.3e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ALG11_N PF15924.5 ORY76869.1 - 2.9e-81 272.5 0.1 4.6e-81 271.9 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 ORY76869.1 - 2.1e-26 92.5 0.0 3.8e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF202 PF02656.15 ORY76869.1 - 8.4e-19 67.8 10.6 2e-17 63.3 5.6 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF202) Glyco_trans_1_4 PF13692.6 ORY76869.1 - 4.1e-11 43.5 0.1 1.1e-10 42.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY76869.1 - 0.022 14.8 0.1 0.052 13.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ORY76869.1 - 0.073 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 AAA PF00004.29 ORY76870.1 - 1.1e-39 135.9 0.0 1.8e-39 135.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY76870.1 - 4.1e-09 36.1 0.0 1.1e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY76870.1 - 8e-07 28.9 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY76870.1 - 4.1e-06 27.1 0.5 0.00076 19.8 0.5 3.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY76870.1 - 4.7e-06 26.7 0.4 0.00027 20.9 0.5 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORY76870.1 - 5e-06 26.6 0.0 9.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY76870.1 - 6.4e-06 26.7 0.1 0.00016 22.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 ORY76870.1 - 0.00019 21.6 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY76870.1 - 0.00021 20.8 0.2 0.0017 17.7 0.2 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ORY76870.1 - 0.00042 20.5 0.0 0.00093 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 ORY76870.1 - 0.00054 19.4 0.1 1.1 8.6 0.0 2.7 3 0 0 3 3 3 2 Bacterial TniB protein AAA_25 PF13481.6 ORY76870.1 - 0.00076 19.1 0.4 0.042 13.4 0.3 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY76870.1 - 0.00078 20.0 0.0 0.0021 18.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 ORY76870.1 - 0.00079 19.8 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.15 ORY76870.1 - 0.00084 19.3 0.2 0.0036 17.2 0.1 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain ATPase PF06745.13 ORY76870.1 - 0.00087 18.7 0.0 0.34 10.2 0.0 2.5 1 1 2 3 3 3 1 KaiC AAA_24 PF13479.6 ORY76870.1 - 0.002 17.9 0.1 0.0043 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY76870.1 - 0.0041 17.1 0.1 0.0084 16.0 0.1 1.5 1 0 0 1 1 1 1 NACHT domain Sigma54_activ_2 PF14532.6 ORY76870.1 - 0.0053 16.9 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORY76870.1 - 0.0062 16.3 0.0 0.036 13.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 ORY76870.1 - 0.0067 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Guanylate_kin PF00625.21 ORY76870.1 - 0.0069 16.1 0.4 0.22 11.2 0.0 3.0 3 1 1 4 4 4 1 Guanylate kinase IstB_IS21 PF01695.17 ORY76870.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 ORY76870.1 - 0.011 15.3 0.3 0.045 13.3 0.0 2.1 4 0 0 4 4 2 0 P-loop containing dynein motor region TsaE PF02367.17 ORY76870.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 ORY76870.1 - 0.014 15.8 0.1 0.042 14.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ORY76870.1 - 0.018 14.2 0.4 0.067 12.4 0.1 2.0 2 1 1 3 3 3 0 TIP49 P-loop domain Bac_DnaA PF00308.18 ORY76870.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_28 PF13521.6 ORY76870.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY76870.1 - 0.02 14.8 0.1 0.086 12.7 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 ORY76870.1 - 0.038 13.1 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 ORY76870.1 - 0.04 13.2 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 ORY76870.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY76870.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Nitr_red_bet_C PF14711.6 ORY76870.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal Parvo_NS1 PF01057.17 ORY76870.1 - 0.15 11.2 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 APG5 PF04106.12 ORY76870.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy protein Apg5 Sugar_tr PF00083.24 ORY76871.1 - 1.8e-111 373.2 27.7 2.1e-111 373.0 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY76871.1 - 2.7e-27 95.7 22.9 2.7e-27 95.7 22.9 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 ORY76872.1 - 3.8e-60 203.4 0.1 8.5e-60 202.2 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY76872.1 - 1.3e-43 148.7 0.1 2e-43 148.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY76872.1 - 3.7e-09 36.8 0.2 5.8e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 ORY76872.1 - 0.046 13.1 0.1 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PEP_hydrolase PF09370.10 ORY76872.1 - 0.061 12.5 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like rhaM PF05336.13 ORY76873.1 - 5e-32 110.2 0.1 5.6e-32 110.0 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase TPPK_C PF12555.8 ORY76874.1 - 0.57 10.3 3.4 82 3.4 0.0 3.4 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal NUMOD4 PF07463.11 ORY76875.1 - 0.19 12.0 0.1 0.31 11.3 0.1 1.3 1 0 0 1 1 1 0 NUMOD4 motif COX7C PF02935.16 ORY76875.1 - 0.27 11.5 0.9 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc AF-4 PF05110.13 ORY76875.1 - 0.71 7.9 8.6 0.73 7.8 8.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3759 PF12585.8 ORY76876.1 - 3.5e-26 91.0 6.7 1.2e-25 89.3 6.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) MFS_1 PF07690.16 ORY76877.1 - 9.5e-36 123.4 30.6 1.3e-35 123.0 30.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3149 PF11346.8 ORY76877.1 - 1.1 8.9 0.0 1.1 8.9 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3149) Asp PF00026.23 ORY76878.1 - 2e-110 369.1 0.1 2.3e-110 368.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY76878.1 - 2.8e-14 53.7 0.3 1.6e-11 44.8 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY76878.1 - 6.4e-07 29.3 0.0 3.4e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 ORY76878.1 - 0.00068 20.1 0.0 7.2 7.3 0.0 3.4 2 1 1 3 3 3 3 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY76878.1 - 0.0032 18.1 0.1 4.9 7.9 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease Med11 PF10280.9 ORY76879.1 - 1.2e-11 45.2 0.1 3.2e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Mediator complex protein Spore_coat_CotO PF14153.6 ORY76879.1 - 0.44 10.4 5.7 0.64 9.9 5.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3123 PF11321.8 ORY76879.1 - 0.68 10.6 0.1 0.68 10.6 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3123) Voldacs PF03517.13 ORY76879.1 - 1.1 9.4 4.1 2.2 8.4 4.1 1.4 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling Pkinase PF00069.25 ORY76880.1 - 8.2e-71 238.5 0.0 9.8e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY76880.1 - 1.6e-34 119.4 0.0 2.1e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY76880.1 - 0.00048 19.2 0.1 0.026 13.5 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 ORY76880.1 - 0.018 14.4 0.0 0.047 13.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 ORY76880.1 - 0.023 14.6 0.9 1.5 8.7 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family AAA_2 PF07724.14 ORY76883.1 - 3.9e-46 157.3 0.0 4.7e-42 144.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 ORY76883.1 - 1.8e-32 111.4 0.9 1.8e-32 111.4 0.9 2.3 1 1 0 2 2 2 1 AAA lid domain AAA PF00004.29 ORY76883.1 - 2.6e-21 76.4 0.1 2.4e-09 37.7 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY76883.1 - 2.1e-16 60.2 1.0 3.4e-12 46.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY76883.1 - 4.1e-12 46.8 2.4 0.00011 22.6 0.1 4.6 3 1 1 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 ORY76883.1 - 5.5e-11 42.4 0.3 6.5e-08 32.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 ORY76883.1 - 9e-10 38.9 1.4 0.021 14.7 0.1 4.2 3 1 1 4 4 4 3 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORY76883.1 - 1.4e-08 34.8 0.0 0.0013 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORY76883.1 - 2.7e-07 30.3 0.0 0.00081 18.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 ORY76883.1 - 8.6e-07 29.3 4.7 0.0055 17.0 0.2 4.2 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.6 ORY76883.1 - 5.4e-06 27.0 0.1 0.21 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY76883.1 - 1.1e-05 25.5 0.5 0.11 12.4 0.0 3.2 3 0 0 3 3 3 2 NACHT domain IstB_IS21 PF01695.17 ORY76883.1 - 1.2e-05 25.1 0.0 0.041 13.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 ORY76883.1 - 2.5e-05 24.1 2.0 0.14 11.9 0.0 3.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 ORY76883.1 - 2.7e-05 23.7 0.1 0.039 13.4 0.1 3.9 3 1 0 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 ORY76883.1 - 3.1e-05 24.3 0.1 0.16 12.4 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Zeta_toxin PF06414.12 ORY76883.1 - 6.6e-05 22.3 0.1 0.0091 15.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 ORY76883.1 - 9.6e-05 21.9 2.5 0.18 11.2 0.1 3.2 3 1 0 3 3 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORY76883.1 - 0.00025 21.0 0.1 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 ORY76883.1 - 0.00029 20.9 0.0 1.1 9.3 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_23 PF13476.6 ORY76883.1 - 0.00033 21.2 2.0 0.56 10.7 1.1 2.8 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 ORY76883.1 - 0.0005 19.2 0.0 0.049 12.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DNA_pol3_delta2 PF13177.6 ORY76883.1 - 0.00094 19.0 0.0 0.069 12.9 0.0 3.3 3 1 0 3 3 3 1 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 ORY76883.1 - 0.00096 19.1 0.3 1.4 8.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 ORY76883.1 - 0.00099 19.3 0.1 0.33 11.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY76883.1 - 0.0022 17.8 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 ORY76883.1 - 0.0026 17.0 0.7 0.47 9.6 0.2 2.8 2 2 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 ORY76883.1 - 0.0054 17.1 2.6 0.19 12.1 0.7 3.2 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY76883.1 - 0.006 16.3 0.6 1.3 8.8 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY76883.1 - 0.014 15.0 3.7 2.1 7.9 0.0 3.7 3 1 1 4 4 4 0 AAA domain TIP49 PF06068.13 ORY76883.1 - 0.014 14.6 1.8 0.31 10.2 0.0 2.6 2 1 0 3 3 3 0 TIP49 P-loop domain AAA_3 PF07726.11 ORY76883.1 - 0.015 15.2 0.4 2 8.3 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY76883.1 - 0.018 15.6 0.8 0.51 10.9 0.0 2.8 3 0 0 3 3 2 0 ABC transporter PhoH PF02562.16 ORY76883.1 - 0.02 14.4 0.2 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SRP54 PF00448.22 ORY76883.1 - 0.033 13.8 0.4 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 ORY76883.1 - 0.037 14.2 0.1 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_6 PF12774.7 ORY76883.1 - 0.066 12.2 0.2 0.32 9.9 0.0 2.0 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region DUF853 PF05872.12 ORY76883.1 - 0.076 11.6 0.1 0.15 10.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2075 PF09848.9 ORY76883.1 - 0.084 12.1 0.5 0.78 8.9 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 ORY76883.1 - 0.085 13.1 9.1 1.2 9.4 0.0 3.7 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 ORY76883.1 - 0.088 12.0 0.1 10 5.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 ORY76883.1 - 0.26 11.0 12.7 0.35 10.5 1.2 4.1 2 2 1 3 3 3 0 AAA domain NTPase_1 PF03266.15 ORY76883.1 - 0.78 9.6 7.1 8.1 6.3 1.7 3.3 3 1 0 3 3 2 0 NTPase ArsA_ATPase PF02374.15 ORY76883.1 - 1.1 8.4 2.6 3 6.9 0.0 2.6 3 0 0 3 3 3 0 Anion-transporting ATPase F1F0-ATPsyn_F PF10791.9 ORY76887.1 - 8.5e-38 128.7 0.1 9.3e-38 128.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 ORY76887.1 - 1.3e-05 25.5 0.0 1.5e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f Xpo1 PF08389.12 ORY76888.1 - 1.5e-08 34.8 0.0 8.6e-08 32.4 0.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 ORY76888.1 - 3.2e-08 33.4 0.2 2.7e-07 30.4 0.3 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 ORY76888.1 - 3e-06 27.2 0.2 1.6e-05 24.8 0.0 2.5 3 0 0 3 3 3 1 Importin 13 repeat Importin_rep PF18773.1 ORY76888.1 - 0.00036 20.2 0.2 0.00064 19.4 0.2 1.4 1 0 0 1 1 1 1 Importin 13 repeat Reticulon PF02453.17 ORY76888.1 - 0.14 12.2 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 Reticulon adh_short PF00106.25 ORY76889.1 - 1.2e-13 51.0 0.5 4.4e-13 49.1 0.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY76889.1 - 1.6e-11 44.2 0.0 2.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 ORY76889.1 - 0.075 12.3 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Arf PF00025.21 ORY76890.1 - 8.1e-77 256.6 0.1 9e-77 256.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY76890.1 - 1.1e-14 54.6 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY76890.1 - 5.9e-14 51.9 0.0 7e-14 51.6 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY76890.1 - 4.3e-13 49.2 0.0 4.5e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY76890.1 - 7.2e-12 45.1 1.2 3.4e-09 36.3 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY76890.1 - 7.9e-11 41.7 0.0 9.4e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY76890.1 - 1.8e-06 28.0 0.0 2.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY76890.1 - 0.024 14.0 0.7 0.067 12.5 0.7 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CRISPR_Cas2 PF09827.9 ORY76890.1 - 0.038 14.2 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas2 CPSF100_C PF13299.6 ORY76891.1 - 1e-34 120.2 0.8 8e-34 117.3 0.0 2.6 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_6 PF16661.5 ORY76891.1 - 1.6e-32 112.5 0.0 3.6e-30 104.9 0.0 3.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 ORY76891.1 - 5.4e-17 62.1 0.0 1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 ORY76891.1 - 0.0003 20.6 0.0 0.00082 19.3 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain CoA_transf_3 PF02515.17 ORY76893.1 - 1.8e-129 432.1 0.0 2.1e-129 431.8 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III adh_short PF00106.25 ORY76894.1 - 8.2e-17 61.3 0.0 4.5e-12 45.8 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY76894.1 - 1.3e-09 37.9 0.0 2.9e-09 36.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY76894.1 - 7.4e-09 35.8 0.5 1.4e-08 34.8 0.3 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 ORY76894.1 - 6.4e-06 26.2 0.4 1.2e-05 25.3 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY76894.1 - 0.001 18.6 0.1 0.002 17.6 0.1 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY76894.1 - 0.0047 16.4 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY76894.1 - 0.1 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORY76894.1 - 0.16 11.5 0.2 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Yip1 PF04893.17 ORY76895.1 - 5.3e-07 29.5 23.8 4e-06 26.6 23.6 1.9 1 1 0 1 1 1 1 Yip1 domain F-box-like PF12937.7 ORY76897.1 - 0.00013 21.8 0.1 0.00022 21.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like FRG1 PF06229.12 ORY76897.1 - 0.024 14.4 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 FRG1-like domain Ribosomal_L12_N PF16320.5 ORY76898.1 - 0.45 10.3 3.2 1.1 9.1 3.2 1.6 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain GSH_synth_ATP PF03917.17 ORY76899.1 - 3.1e-116 388.2 0.0 6.3e-115 383.9 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 ORY76899.1 - 1.4e-26 92.9 0.0 2.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase WD40 PF00400.32 ORY76900.1 - 0.00033 21.4 0.1 0.011 16.6 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY76900.1 - 0.0062 16.8 0.0 0.73 10.2 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain LRR_4 PF12799.7 ORY76901.1 - 0.33 11.4 11.4 5.4 7.6 0.5 4.6 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY76901.1 - 0.63 9.8 7.7 0.34 10.7 0.2 3.7 5 0 0 5 5 5 0 Leucine rich repeat Abhydrolase_6 PF12697.7 ORY76902.1 - 2.3e-26 93.8 0.8 2.7e-26 93.5 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY76902.1 - 1.8e-13 50.3 0.7 2.7e-13 49.8 0.7 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY76902.1 - 4.6e-10 39.6 0.0 5.4e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 ORY76902.1 - 1.4e-06 28.6 0.0 2.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 ORY76902.1 - 0.00039 20.1 0.0 0.00061 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 ORY76902.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 ORY76902.1 - 0.029 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 ORY76902.1 - 0.099 12.4 0.5 0.69 9.7 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.20 ORY76902.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Ribosomal_L11_N PF03946.14 ORY76903.1 - 2.2e-24 85.0 0.2 3.6e-24 84.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY76903.1 - 2.1e-15 57.0 0.1 3.6e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain WD40 PF00400.32 ORY76904.1 - 1.2e-44 149.4 14.8 3.2e-08 34.1 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY76904.1 - 1.2e-11 44.8 0.6 0.021 15.1 0.0 5.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY76904.1 - 0.00051 18.8 2.8 0.088 11.4 0.2 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 ORY76904.1 - 0.00092 17.8 0.1 1 7.8 0.1 2.5 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 ORY76904.1 - 0.0041 16.5 0.0 0.22 10.8 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain PD40 PF07676.12 ORY76904.1 - 0.0055 16.6 0.7 7.7 6.6 0.0 4.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat DUF1416 PF07210.12 ORY76904.1 - 0.094 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) PGM_PMM_I PF02878.16 ORY76905.1 - 8e-35 119.6 0.1 1.2e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ORY76905.1 - 5.4e-25 87.8 0.0 9.8e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORY76905.1 - 1e-12 48.5 0.0 2.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORY76905.1 - 9.7e-07 28.9 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NTP_transf_3 PF12804.7 ORY76905.1 - 0.083 13.2 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain 4HFCP_synth PF04476.13 ORY76905.1 - 0.18 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 4-HFC-P synthase tRNA-synt_1e PF01406.19 ORY76907.1 - 3.8e-121 404.1 0.0 1.1e-120 402.6 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ORY76907.1 - 3.2e-09 36.0 1.4 1.8e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY76907.1 - 2.2e-05 22.9 0.1 0.0012 17.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.18 ORY76907.1 - 0.035 13.0 0.1 4 6.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) DALR_2 PF09190.11 ORY76907.1 - 0.091 13.3 0.4 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 DALR domain MFS_1 PF07690.16 ORY76908.1 - 2e-29 102.6 34.7 5.4e-29 101.2 35.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MAGE PF01454.19 ORY76909.1 - 0.074 12.7 1.2 6 6.5 0.7 2.2 2 0 0 2 2 2 0 MAGE family Comm PF15957.5 ORY76909.1 - 1.4 9.3 4.8 17 5.8 3.0 2.8 3 0 0 3 3 3 0 Commissureless CK_II_beta PF01214.18 ORY76910.1 - 4e-08 33.3 0.0 7.2e-08 32.5 0.0 1.4 1 1 1 2 2 2 1 Casein kinase II regulatory subunit CK_II_beta PF01214.18 ORY76911.1 - 1.3e-19 70.8 0.0 2.1e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Cast PF10174.9 ORY76912.1 - 0.076 11.2 0.0 0.097 10.9 0.0 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF1501 PF07394.12 ORY76913.1 - 0.06 12.4 0.1 0.067 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SH3_11 PF18103.1 ORY76917.1 - 0.11 12.7 0.2 0.42 10.8 0.1 2.0 2 0 0 2 2 2 0 Retroviral integrase C-terminal SH3 domain MAS20 PF02064.15 ORY76918.1 - 2.3e-39 134.5 1.5 5e-39 133.3 1.5 1.6 1 0 0 1 1 1 1 MAS20 protein import receptor DUF4378 PF14309.6 ORY76918.1 - 0.035 14.5 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) PET117 PF15786.5 ORY76918.1 - 0.05 13.9 0.2 0.087 13.1 0.2 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial MSA-2c PF12238.8 ORY76918.1 - 0.74 9.8 5.6 1.6 8.7 5.5 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c CbiJ PF02571.14 ORY76920.1 - 0.16 11.4 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK His_Phos_1 PF00300.22 ORY76921.1 - 7.5e-40 136.7 0.0 8.9e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sortase PF04203.13 ORY76921.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Sortase domain AMP-binding PF00501.28 ORY76922.1 - 4.1e-68 229.9 0.0 5.2e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY76922.1 - 6.9e-05 23.7 0.1 0.00026 21.9 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ku PF02735.16 ORY76922.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain DTHCT PF08070.11 ORY76923.1 - 1.2 9.9 9.7 2.2 9.1 1.0 2.8 2 1 0 2 2 2 0 DTHCT (NUC029) region ETF PF01012.21 ORY76924.1 - 8.5e-47 159.4 2.0 1.1e-46 159.0 2.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PAP2_3 PF14378.6 ORY76925.1 - 0.043 13.5 0.1 0.063 13.0 0.1 1.2 1 0 0 1 1 1 0 PAP2 superfamily PIG-L PF02585.17 ORY76926.1 - 1e-23 84.4 0.0 1.4e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HisG PF01634.18 ORY76927.1 - 4.4e-51 173.0 0.2 5.7e-51 172.7 0.2 1.1 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ORY76927.1 - 6.8e-29 99.8 1.1 9.7e-29 99.3 0.1 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain NMT1 PF09084.11 ORY76927.1 - 0.0026 17.7 0.1 0.0036 17.3 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like F-box-like PF12937.7 ORY76929.1 - 0.00044 20.1 0.2 0.00093 19.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like RIO1 PF01163.22 ORY76930.1 - 1.2e-61 207.6 0.1 2.5e-61 206.6 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY76930.1 - 0.044 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY76930.1 - 5.7 5.6 11.7 6.2 5.5 2.9 2.9 3 0 0 3 3 3 0 Fungal protein kinase Rbsn PF11464.8 ORY76931.1 - 0.049 13.4 0.3 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Mob1_phocein PF03637.17 ORY76932.1 - 3.3e-78 261.5 0.2 3.8e-78 261.3 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DNA_pol_delta_4 PF04081.13 ORY76933.1 - 1.4e-19 70.7 0.0 1.7e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 GHBP PF12772.7 ORY76933.1 - 0.008 15.7 0.4 0.013 15.1 0.4 1.4 1 0 0 1 1 1 1 Growth hormone receptor binding Ribosomal_60s PF00428.19 ORY76933.1 - 1.2 9.7 6.7 2.9 8.5 6.2 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein LRR_6 PF13516.6 ORY76934.1 - 0.044 13.8 0.1 0.17 12.0 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich repeat DehI PF10778.9 ORY76934.1 - 0.045 13.9 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 Halocarboxylic acid dehydrogenase DehI SAC3_GANP PF03399.16 ORY76935.1 - 4.8e-78 262.5 0.0 1.2e-77 261.2 0.0 1.6 1 1 0 1 1 1 1 SAC3/GANP family DUF2985 PF11204.8 ORY76937.1 - 2.2e-19 69.4 3.3 4.9e-19 68.3 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sensor PF13796.6 ORY76937.1 - 0.024 14.7 2.3 0.03 14.4 0.2 2.0 2 0 0 2 2 2 0 Putative sensor RCR PF12273.8 ORY76937.1 - 0.064 13.9 0.1 0.19 12.4 0.1 1.9 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TRAPPC10 PF12584.8 ORY76938.1 - 6.4e-21 74.7 0.0 1.6e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Nup192 PF11894.8 ORY76938.1 - 0.027 11.6 0.0 0.039 11.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex scaffold, nucleoporins 186/192/205 Gryzun-like PF12742.7 ORY76938.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Mannosyl_trans PF05007.13 ORY76939.1 - 3.9e-72 243.2 12.0 8e-72 242.2 12.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 ORY76939.1 - 3.4e-07 29.6 14.9 1.2e-06 27.8 14.9 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 ORY76939.1 - 2e-06 27.7 19.4 2e-06 27.7 19.4 2.6 2 1 1 3 3 3 1 Glycosyltransferase family 87 CbtA_toxin PF06755.12 ORY76940.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.5 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system AAA_11 PF13086.6 ORY76944.1 - 1.1e-54 186.0 0.0 1.1e-54 186.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_12 PF13087.6 ORY76944.1 - 1.1e-48 165.6 0.0 2.5e-48 164.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY76944.1 - 2e-11 43.9 0.0 4.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 ORY76944.1 - 1.5e-09 38.3 0.0 2.3e-08 34.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ORY76944.1 - 2.2e-07 30.8 0.0 0.0096 15.7 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 ORY76944.1 - 0.00014 21.5 0.0 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 ORY76944.1 - 0.0022 17.5 0.1 0.81 9.1 0.0 3.2 4 0 0 4 4 4 1 PhoH-like protein ResIII PF04851.15 ORY76944.1 - 0.0036 17.3 0.1 0.4 10.7 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY76944.1 - 0.0044 17.3 0.0 0.18 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY76944.1 - 0.015 15.7 0.0 0.067 13.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.14 ORY76944.1 - 0.023 14.6 0.0 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Helicase NTPase_1 PF03266.15 ORY76944.1 - 0.053 13.4 5.3 1.1 9.2 0.6 2.6 3 0 0 3 3 3 0 NTPase AAA_5 PF07728.14 ORY76944.1 - 0.059 13.4 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY76944.1 - 0.062 12.9 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY76944.1 - 0.066 12.4 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 ORY76944.1 - 0.082 12.6 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SPX PF03105.19 ORY76944.1 - 8.2 6.2 11.6 18 5.1 11.6 1.5 1 0 0 1 1 1 0 SPX domain Zn_clus PF00172.18 ORY76945.1 - 0.9 9.7 8.8 1.6 8.9 8.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NOT2_3_5 PF04153.18 ORY76947.1 - 5.8e-34 117.0 1.7 5.8e-34 117.0 1.7 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family TFIIA PF03153.13 ORY76947.1 - 0.39 10.7 31.3 0.64 10.0 31.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_membrane PF00664.23 ORY76948.1 - 1.2e-85 287.5 22.3 5.7e-46 157.4 8.9 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY76948.1 - 1.5e-63 213.3 0.0 9.3e-32 110.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY76948.1 - 3.7e-12 46.2 3.2 0.0002 20.9 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY76948.1 - 2.3e-07 31.0 0.8 0.47 10.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY76948.1 - 7.9e-06 26.4 3.6 0.0056 17.1 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORY76948.1 - 5.1e-05 22.9 4.7 0.11 12.2 0.2 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ORY76948.1 - 9.4e-05 22.2 0.1 8.3 6.1 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_30 PF13604.6 ORY76948.1 - 0.00023 21.0 2.6 0.61 9.8 0.1 3.5 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 ORY76948.1 - 0.00036 19.5 3.6 0.34 9.6 0.0 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_18 PF13238.6 ORY76948.1 - 0.00048 20.7 0.0 0.21 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY76948.1 - 0.00056 20.2 4.9 0.69 10.2 0.3 4.0 2 2 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORY76948.1 - 0.0008 19.7 4.0 0.55 10.5 0.0 3.5 2 2 0 3 3 3 2 AAA domain DUF87 PF01935.17 ORY76948.1 - 0.0012 19.0 1.7 0.11 12.6 0.1 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 ORY76948.1 - 0.0015 18.5 0.2 0.99 9.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 ORY76948.1 - 0.025 13.8 0.2 2.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 ORY76948.1 - 0.029 14.5 0.1 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ORY76948.1 - 0.03 14.2 0.3 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 ORY76948.1 - 0.038 13.7 0.1 0.83 9.4 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 ORY76948.1 - 0.045 14.0 0.3 28 5.0 0.2 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ORY76948.1 - 0.057 13.0 0.3 13 5.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 ORY76948.1 - 0.085 13.3 0.2 16 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY76948.1 - 0.15 11.4 0.1 16 4.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 ORY76948.1 - 0.15 12.0 0.1 18 5.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 ORY76948.1 - 0.23 10.6 0.1 2.5 7.2 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit CoaE PF01121.20 ORY76948.1 - 0.64 9.7 2.5 3.1 7.4 0.2 2.5 2 0 0 2 2 2 0 Dephospho-CoA kinase UvrD_C PF13361.6 ORY76949.1 - 5.9e-07 29.2 0.0 2e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 ORY76949.1 - 1.8e-05 24.4 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Nic96 PF04097.14 ORY76949.1 - 6.8e-05 21.5 0.6 0.0025 16.3 0.2 2.2 2 0 0 2 2 2 1 Nup93/Nic96 AAA_22 PF13401.6 ORY76949.1 - 0.019 15.2 0.0 0.078 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain SPO22 PF08631.10 ORY76949.1 - 0.021 14.3 1.4 0.047 13.2 0.5 2.1 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like AbiEi_3 PF11459.8 ORY76949.1 - 0.11 12.2 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system RAB3GAP2_C PF14656.6 ORY76949.1 - 0.17 10.1 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus ParE_toxin PF05016.15 ORY76949.1 - 0.76 10.4 2.9 5.9 7.6 0.0 3.5 3 0 0 3 3 3 0 ParE toxin of type II toxin-antitoxin system, parDE TPR_19 PF14559.6 ORY76949.1 - 2.8 8.5 12.3 55 4.4 0.1 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY76949.1 - 3.3 8.0 22.0 2.7 8.3 0.3 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat Pkinase PF00069.25 ORY76950.1 - 2.4e-39 135.3 0.0 5.3e-13 48.9 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 ORY76950.1 - 3.6e-20 72.4 0.2 1.1e-13 51.1 0.0 3.9 4 1 0 4 4 4 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY76950.1 - 0.0018 17.1 0.0 0.0049 15.7 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase DUF4229 PF14012.6 ORY76951.1 - 0.021 14.9 0.5 0.043 13.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Sporozoite_P67 PF05642.11 ORY76951.1 - 0.13 10.3 4.4 0.19 9.7 4.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen IMUP PF15761.5 ORY76951.1 - 0.14 12.9 0.2 0.14 12.9 0.2 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF3446 PF11928.8 ORY76951.1 - 2.1 8.7 13.9 2.6 8.4 8.6 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Abhydrolase_3 PF07859.13 ORY76952.1 - 5.9e-27 94.9 0.2 7.6e-27 94.5 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY76952.1 - 0.0012 19.4 1.1 0.0012 19.4 1.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.28 ORY76952.1 - 0.0029 16.5 0.1 0.65 8.8 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Say1_Mug180 PF10340.9 ORY76952.1 - 0.29 10.0 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Glyco_hydro_16 PF00722.21 ORY77184.1 - 3.3e-10 39.7 1.9 2.2e-09 37.1 1.9 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SOG2 PF10428.9 ORY77184.1 - 5.2 6.2 11.3 8 5.5 11.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CxC6 PF18721.1 ORY77185.1 - 2.9e-16 59.5 3.0 5.8e-16 58.5 3.0 1.5 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases Meis_PKNOX_N PF16493.5 ORY77185.1 - 0.28 11.5 0.9 0.81 10.1 0.0 2.0 2 0 0 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 RPAP2_Rtr1 PF04181.13 ORY77185.1 - 0.38 11.1 2.3 15 6.0 0.7 2.6 1 1 1 2 2 2 0 Rtr1/RPAP2 family Rad60-SLD PF11976.8 ORY77186.1 - 7.5e-11 41.7 0.0 1.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY77186.1 - 0.0095 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family ATP-synt_C PF00137.21 ORY77187.1 - 3.1e-31 107.5 39.4 2.5e-19 69.4 15.9 2.7 3 0 0 3 3 3 2 ATP synthase subunit C IncD PF17628.2 ORY77187.1 - 6.7 6.5 7.2 5.8 6.7 5.9 1.6 1 1 0 1 1 1 0 Inclusion membrane protein D WD40 PF00400.32 ORY77188.1 - 1.4e-12 47.9 11.5 0.0078 17.0 0.0 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat EAF PF09816.9 ORY77190.1 - 1e-17 64.4 0.0 2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Serglycin PF04360.12 ORY77190.1 - 0.035 14.0 0.2 0.035 14.0 0.2 3.0 3 0 0 3 3 3 0 Serglycin TPR_12 PF13424.6 ORY77191.1 - 3.3e-12 46.5 13.7 2.7e-06 27.6 0.2 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat SNAP PF14938.6 ORY77191.1 - 2.1e-11 43.8 1.1 3.7e-09 36.4 1.0 2.2 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 ORY77191.1 - 0.0022 17.7 9.2 0.67 9.9 0.2 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY77191.1 - 0.0048 16.9 12.8 0.42 10.8 0.1 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY77191.1 - 0.01 16.0 8.1 4.8 7.6 0.2 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 ORY77191.1 - 0.039 13.4 0.9 1.9 7.9 0.9 2.8 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF4662 PF15578.6 ORY77191.1 - 0.042 13.7 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) TPR_6 PF13174.6 ORY77191.1 - 0.16 12.7 8.9 1.9 9.3 0.1 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY77191.1 - 0.52 10.5 7.3 4.6 7.5 0.1 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY77191.1 - 1.7 9.4 10.7 1.1 9.9 0.7 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY77192.1 - 0.065 13.4 1.7 9.8 6.6 0.1 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.18 ORY77193.1 - 4.1e-05 23.6 11.2 6.6e-05 22.9 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCCL PF03815.19 ORY77195.1 - 1e-16 60.8 0.1 1.7e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Wzy_C PF04932.15 ORY77195.1 - 0.17 11.5 6.4 4.1 7.0 1.0 3.1 3 0 0 3 3 3 0 O-Antigen ligase Pkinase PF00069.25 ORY77196.1 - 9.2e-63 212.1 0.1 1.3e-43 149.3 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY77196.1 - 4.4e-27 95.0 0.1 1.1e-20 74.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY77196.1 - 7.3e-09 35.0 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY77196.1 - 5.4e-05 22.6 0.3 0.0016 17.8 0.0 2.6 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY77196.1 - 0.00059 19.8 4.4 0.017 15.0 0.2 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY77196.1 - 0.0047 16.3 0.0 0.014 14.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 ORY77196.1 - 0.019 15.6 1.0 0.038 14.7 1.0 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 ORY77196.1 - 0.031 13.0 0.0 0.072 11.9 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 ORY77196.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 ORY77196.1 - 0.055 12.5 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 ORY77196.1 - 0.077 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase F-box-like PF12937.7 ORY77197.1 - 0.00037 20.3 6.4 0.00039 20.3 0.7 3.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY77197.1 - 0.037 13.9 1.1 2.5 8.1 0.1 3.3 2 0 0 2 2 2 0 F-box domain Amidohydro_1 PF01979.20 ORY77198.1 - 2.9e-53 181.4 0.0 3.6e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY77198.1 - 1.2e-08 34.8 0.0 2.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ORY77198.1 - 0.0021 17.5 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase YdjC PF04794.12 ORY77198.1 - 0.07 13.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 YdjC-like protein DUF3818 PF12825.7 ORY77199.1 - 1.7e-130 435.0 0.1 2.9e-130 434.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 ORY77199.1 - 1.7e-35 121.9 0.0 4.5e-35 120.5 0.0 1.8 1 0 0 1 1 1 1 PX-associated PX PF00787.24 ORY77199.1 - 1.1e-08 35.0 1.4 5.1e-08 32.9 0.0 2.8 4 1 0 4 4 4 1 PX domain R3H-assoc PF13902.6 ORY77200.1 - 0.095 13.1 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 R3H-associated N-terminal domain F-box-like PF12937.7 ORY77201.1 - 5.5e-05 23.0 0.8 0.00018 21.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like adh_short PF00106.25 ORY77202.1 - 1.1e-26 93.5 0.0 4.6e-22 78.4 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY77202.1 - 4e-18 65.8 0.0 5.3e-17 62.2 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY77202.1 - 3.4e-10 40.1 0.0 7.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 ORY77202.1 - 0.0083 16.2 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 ORY77202.1 - 0.15 11.4 0.2 0.25 10.6 0.2 1.3 1 0 0 1 1 1 0 ThiF family F-box-like PF12937.7 ORY77203.1 - 6.9e-07 29.1 0.2 1.9e-06 27.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY77203.1 - 0.13 12.2 0.9 0.84 9.6 0.9 2.3 1 1 0 1 1 1 0 F-box domain Tubulin PF00091.25 ORY77205.1 - 4.3e-68 229.4 0.0 5.8e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY77205.1 - 1.7e-49 167.2 0.0 2.6e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY77205.1 - 0.00038 20.2 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain WH2 PF02205.20 ORY77206.1 - 3.6e-08 33.0 2.0 2.2e-06 27.3 1.2 2.8 2 0 0 2 2 2 2 WH2 motif Baculo_PEP_C PF04513.12 ORY77209.1 - 0.18 11.9 1.6 0.45 10.5 0.0 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDC37_N PF03234.14 ORY77209.1 - 3.1 8.7 13.9 0.87 10.5 2.0 3.2 2 1 1 3 3 3 0 Cdc37 N terminal kinase binding ING PF12998.7 ORY77209.1 - 6 7.5 7.4 0.57 10.8 0.8 2.7 3 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Fib_alpha PF08702.10 ORY77209.1 - 8.5 6.6 7.1 1.7 8.8 1.8 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cyt-b5 PF00173.28 ORY77210.1 - 5.3e-14 52.1 0.0 9.8e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 ORY77210.1 - 1.1e-13 51.6 23.1 1.7e-13 51.0 23.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Tim29 PF10171.9 ORY77210.1 - 0.047 13.2 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Aminotran_1_2 PF00155.21 ORY77211.1 - 6.3e-17 61.8 0.0 2.3e-09 36.9 0.0 3.6 2 1 0 2 2 2 2 Aminotransferase class I and II DUF1748 PF08520.10 ORY77212.1 - 1.1e-24 86.1 0.0 1.2e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) eIF2_C PF09173.11 ORY77213.1 - 7.8e-35 119.0 0.4 2.3e-34 117.5 0.4 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ORY77213.1 - 2e-23 83.0 0.4 1.7e-22 79.9 0.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY77213.1 - 6.1e-09 36.1 1.1 6.1e-09 36.1 1.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 ORY77213.1 - 0.0019 18.2 0.9 0.003 17.5 0.1 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 ORY77213.1 - 0.0086 16.0 1.3 0.013 15.4 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase F-box-like PF12937.7 ORY77215.1 - 3.8e-06 26.7 0.4 3.8e-06 26.7 0.4 2.2 2 0 0 2 2 2 1 F-box-like Chitin_synth_1 PF01644.17 ORY77216.1 - 9.4e-79 263.1 0.1 1.8e-78 262.1 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY77216.1 - 1.5e-29 101.8 0.4 3.1e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY77216.1 - 7.3e-22 77.7 1.6 5.4e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY77216.1 - 0.00064 19.7 10.9 0.0025 17.8 10.9 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DASH_Dam1 PF08653.10 ORY77217.1 - 1.4e-17 63.2 0.0 2.3e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 FoP_duplication PF13865.6 ORY77217.1 - 0.25 11.9 2.4 0.45 11.1 2.4 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Band_7 PF01145.25 ORY77218.1 - 8.1e-25 87.8 1.9 1.1e-24 87.4 1.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family RepB-RCR_reg PF10723.9 ORY77218.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Replication regulatory protein RepB F-box-like PF12937.7 ORY77219.1 - 1.2e-06 28.3 0.4 4.2e-06 26.6 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY77219.1 - 0.053 13.4 0.5 0.25 11.3 0.5 2.2 1 1 0 1 1 1 0 F-box domain PH PF00169.29 ORY77220.1 - 0.0088 16.5 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF2205 PF10224.9 ORY77221.1 - 0.014 15.4 3.6 0.014 15.3 1.0 2.1 1 1 1 2 2 2 0 Short coiled-coil protein Baculo_PEP_C PF04513.12 ORY77221.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 ORY77221.1 - 0.016 14.1 2.8 0.02 13.8 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ING PF12998.7 ORY77221.1 - 0.016 15.8 1.0 0.035 14.7 1.0 1.6 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Phlebovirus_NSM PF07246.11 ORY77221.1 - 0.024 14.0 1.1 0.028 13.8 1.1 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4618 PF15397.6 ORY77221.1 - 0.04 13.3 2.6 0.068 12.6 2.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) TssO PF17561.2 ORY77221.1 - 0.043 13.9 0.2 0.052 13.7 0.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO Fib_alpha PF08702.10 ORY77221.1 - 0.072 13.3 1.5 0.17 12.0 1.6 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Baculo_p24 PF05073.12 ORY77221.1 - 0.08 12.7 0.2 0.18 11.5 0.2 1.5 1 1 0 1 1 1 0 Baculovirus P24 capsid protein Sec5 PF15469.6 ORY77221.1 - 0.08 12.7 1.0 0.17 11.7 0.9 1.5 1 1 0 1 1 1 0 Exocyst complex component Sec5 TBCA PF02970.16 ORY77221.1 - 0.09 13.1 3.2 2.5 8.5 0.5 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor A CENP-F_leu_zip PF10473.9 ORY77221.1 - 0.093 12.7 6.5 0.14 12.2 6.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_UL6 PF01763.16 ORY77221.1 - 0.099 11.1 0.6 0.13 10.8 0.5 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Prominin PF05478.11 ORY77221.1 - 0.1 10.5 0.6 0.29 9.0 0.6 1.5 1 1 0 1 1 1 0 Prominin GCN5L1 PF06320.13 ORY77221.1 - 0.11 12.6 4.4 0.32 11.2 0.6 2.1 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) ALIX_LYPXL_bnd PF13949.6 ORY77221.1 - 0.12 11.7 4.0 0.4 9.9 0.6 2.0 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DUF5082 PF16888.5 ORY77221.1 - 0.12 12.7 1.5 0.51 10.6 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HALZ PF02183.18 ORY77221.1 - 0.14 12.4 2.2 6.1 7.2 0.2 2.9 2 1 1 3 3 3 0 Homeobox associated leucine zipper LPP PF04728.13 ORY77221.1 - 0.17 12.3 2.3 0.73 10.3 0.0 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper CASP_C PF08172.12 ORY77221.1 - 0.58 9.5 4.1 2.3 7.5 4.1 1.8 1 1 0 1 1 1 0 CASP C terminal FAM76 PF16046.5 ORY77221.1 - 0.91 8.8 3.8 1.3 8.3 3.8 1.2 1 0 0 1 1 1 0 FAM76 protein FadA PF09403.10 ORY77221.1 - 1.3 9.5 6.5 4.1 7.9 2.7 2.1 1 1 0 1 1 1 0 Adhesion protein FadA APG6_N PF17675.1 ORY77221.1 - 2.6 8.6 8.2 2.6 8.6 1.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region F-box-like PF12937.7 ORY77222.1 - 3.8e-05 23.5 1.8 0.00011 22.0 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY77222.1 - 6.4 6.8 7.7 23 5.0 0.2 3.6 3 1 0 3 3 3 0 F-box domain RabGAP-TBC PF00566.18 ORY77223.1 - 1.1e-49 169.1 0.2 1.9e-49 168.2 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4864 PF16156.5 ORY77223.1 - 0.17 12.6 0.0 0.34 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) RdRP PF05183.12 ORY77225.1 - 3.4e-144 481.7 0.0 4.2e-144 481.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Pkinase PF00069.25 ORY77226.1 - 9.4e-61 205.5 0.0 1.5e-60 204.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY77226.1 - 2.8e-40 138.2 0.0 3.5e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY77226.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY77226.1 - 0.0084 14.9 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY77226.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 ORY77229.1 - 1.9e-47 161.9 0.0 2.4e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY77229.1 - 1.9e-11 44.4 0.0 6.5e-10 39.4 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY77229.1 - 0.0075 15.6 0.1 0.7 9.1 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY77229.1 - 0.047 13.3 0.0 4.5 6.8 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY77230.1 - 3.2e-44 151.4 0.0 4.3e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY77230.1 - 1.7e-10 41.3 0.0 3.7e-09 37.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY77230.1 - 0.072 12.7 0.8 3 7.3 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY77230.1 - 0.13 11.3 0.0 8.2 5.3 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORY77230.1 - 0.17 11.1 0.1 0.79 8.9 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DPBB_1 PF03330.18 ORY77231.1 - 0.0016 18.7 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY77231.1 - 0.0089 15.9 0.0 0.0089 15.9 0.0 1.8 2 0 0 2 2 2 1 Barwin family Rotamase_2 PF13145.6 ORY77231.1 - 0.027 15.3 8.1 0.044 14.6 8.1 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain UPF0565 PF10561.9 ORY77231.1 - 0.096 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RR_TM4-6 PF06459.12 ORY77231.1 - 0.57 10.0 6.4 0.72 9.6 6.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 ORY77231.1 - 0.89 7.9 13.9 1.2 7.5 13.9 1.0 1 0 0 1 1 1 0 Mpp10 protein Rtf2 PF04641.12 ORY77231.1 - 1.2 8.4 12.9 1.8 7.9 12.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger AP3D1 PF06375.11 ORY77231.1 - 1.7 8.8 10.7 3.6 7.8 10.7 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 XRN_M PF17846.1 ORY77231.1 - 2 7.3 5.3 2.7 6.8 5.3 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RNA_pol_Rpb1_4 PF05000.17 ORY77231.1 - 2.2 8.3 5.5 3.8 7.5 5.5 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 DUF755 PF05501.11 ORY77231.1 - 2.2 8.6 15.9 3.2 8.0 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) RNA_pol_Rpc4 PF05132.14 ORY77231.1 - 4.6 7.7 10.0 7.5 7.0 10.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 GRP PF07172.11 ORY77234.1 - 0.94 10.2 29.4 0.98 10.2 29.4 1.1 1 0 0 1 1 1 0 Glycine rich protein family DUF5610 PF18433.1 ORY77235.1 - 0.042 14.3 0.1 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) TFIIE-A_C PF11521.8 ORY77235.1 - 0.11 12.8 1.8 1.4 9.3 0.2 2.7 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha ALS_ss_C PF10369.9 ORY77237.1 - 2.3e-18 66.2 0.1 3.4e-17 62.4 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 ORY77237.1 - 9.8e-13 47.6 0.1 1.8e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORY77237.1 - 9.2e-08 31.8 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain FGAR-AT_N PF18076.1 ORY77237.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Cu_bind_CorA PF18252.1 ORY77237.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Copper(I)-binding protein CorA R3H PF01424.22 ORY77238.1 - 6e-17 61.4 0.1 1.2e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 ORY77238.1 - 0.0006 19.8 13.2 0.0006 19.8 13.2 12.8 12 1 0 12 12 12 6 NF-X1 type zinc finger Pkinase PF00069.25 ORY77240.1 - 3.8e-63 213.3 0.0 4.6e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY77240.1 - 1.2e-41 142.7 0.0 1.6e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY77240.1 - 7.9e-06 25.4 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY77240.1 - 0.0065 15.3 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY77240.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.7 ORY77241.1 - 0.00038 20.3 0.8 0.0015 18.4 0.8 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY77241.1 - 0.0055 16.6 0.1 0.017 15.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain DUF4125 PF13526.6 ORY77242.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) Nsp1_C PF05064.13 ORY77242.1 - 0.13 12.1 2.0 0.38 10.6 0.3 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region NUP50 PF08911.11 ORY77243.1 - 6.4e-17 62.0 2.1 6.4e-17 62.0 2.1 7.5 6 3 1 7 7 7 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 ORY77243.1 - 1.8e-07 31.4 0.5 4.1e-07 30.3 0.5 1.5 1 1 0 1 1 1 1 RanBP1 domain Amido_AtzD_TrzD PF09663.10 ORY77243.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) DUF4449 PF14613.6 ORY77244.1 - 3.8e-34 118.2 2.1 3.8e-34 118.2 2.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) DUF883 PF05957.13 ORY77244.1 - 0.012 16.1 4.4 0.012 16.1 4.4 5.2 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF883) NuiA PF07924.11 ORY77244.1 - 0.029 14.8 0.2 0.23 11.9 0.0 2.6 3 0 0 3 3 3 0 Nuclease A inhibitor-like protein DNA_methylase PF00145.17 ORY77245.1 - 3.7e-20 72.5 0.0 6.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 ORY77245.1 - 1.5e-07 31.3 0.0 0.0024 17.7 0.0 2.6 2 0 0 2 2 2 2 BAH domain DFP PF04127.15 ORY77245.1 - 0.098 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PTCRA PF15028.6 ORY77246.1 - 0.022 14.4 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Pre-T-cell antigen receptor Macoilin PF09726.9 ORY77247.1 - 0.31 9.6 15.9 0.42 9.1 15.9 1.2 1 0 0 1 1 1 0 Macoilin family RAP1 PF07218.11 ORY77247.1 - 8.5 4.5 21.6 12 4.1 21.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tmemb_cc2 PF10267.9 ORY77247.1 - 9.7 5.2 12.7 15 4.6 12.7 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RhoGAP PF00620.27 ORY77248.1 - 6.1e-25 87.8 0.0 1e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1952 PF09189.10 ORY77248.1 - 0.04 13.7 7.7 0.086 12.7 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1952) HD PF01966.22 ORY77249.1 - 8.6e-05 22.8 2.4 0.00053 20.2 0.5 2.3 2 0 0 2 2 2 1 HD domain Imm63 PF15599.6 ORY77249.1 - 0.058 13.8 0.6 0.13 12.6 0.6 1.5 1 0 0 1 1 1 0 Immunity protein 63 SVWC PF15430.6 ORY77249.1 - 0.17 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Single domain von Willebrand factor type C GDA1_CD39 PF01150.17 ORY77250.1 - 6.9e-90 301.7 0.0 9.2e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PTCRA PF15028.6 ORY77251.1 - 0.024 14.3 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Pre-T-cell antigen receptor DUF3421 PF11901.8 ORY77252.1 - 6.8e-13 48.6 0.0 1.2e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) zf-CRD PF17979.1 ORY77252.1 - 1.7e-12 47.7 0.1 1.7e-12 47.7 0.1 1.9 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions zf-C3HC4_2 PF13923.6 ORY77252.1 - 2.7e-10 39.9 8.2 2.7e-10 39.9 8.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY77252.1 - 6.8e-08 32.2 6.2 6.8e-08 32.2 6.2 3.0 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY77252.1 - 1.5e-07 31.6 8.2 1.5e-07 31.6 8.2 3.6 4 0 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY77252.1 - 2.7e-07 30.5 7.8 2.7e-07 30.5 7.8 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY77252.1 - 5.5e-06 26.1 4.3 5.5e-06 26.1 4.3 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 ORY77252.1 - 0.00012 22.0 1.0 0.00025 21.0 1.0 1.6 1 0 0 1 1 1 1 PBZ domain zf-RING_5 PF14634.6 ORY77252.1 - 0.00013 21.8 4.9 0.00013 21.8 4.9 2.9 3 0 0 3 3 3 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY77252.1 - 0.00014 21.7 6.1 0.00014 21.7 6.1 2.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY77252.1 - 0.0056 16.5 3.9 0.0056 16.5 3.9 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein DUF4776 PF16003.5 ORY77252.1 - 0.94 8.4 3.8 1.6 7.6 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) zf-C3HC4_4 PF15227.6 ORY77252.1 - 8.3 6.7 19.4 0.33 11.1 10.8 2.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING CoA_transf_3 PF02515.17 ORY77253.1 - 1.7e-47 162.3 1.5 1.4e-43 149.5 0.0 3.1 2 2 1 3 3 3 2 CoA-transferase family III NicO PF03824.16 ORY77254.1 - 1.5e-48 165.6 7.2 9.4e-48 163.0 0.2 2.5 2 1 0 2 2 2 2 High-affinity nickel-transport protein MFS_2 PF13347.6 ORY77254.1 - 0.0017 17.0 1.2 0.12 10.9 0.0 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein DUF2269 PF10027.9 ORY77254.1 - 0.019 15.0 3.0 0.2 11.7 0.1 3.0 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) DUF2681 PF10883.8 ORY77254.1 - 0.044 14.2 1.4 0.18 12.2 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2207 PF09972.9 ORY77254.1 - 0.095 11.5 2.4 0.3 9.8 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EphA2_TM PF14575.6 ORY77254.1 - 0.18 12.7 2.0 22 6.0 0.0 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DivIC PF04977.15 ORY77254.1 - 2.6 7.9 4.2 1.7 8.5 1.8 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF5516 PF17637.2 ORY77254.1 - 3.8 7.3 7.5 9.7 6.0 0.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5516) LRR_4 PF12799.7 ORY77255.1 - 0.0091 16.4 4.4 5.1 7.7 0.6 3.8 1 1 4 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY77255.1 - 2 8.4 7.0 0.18 11.7 2.3 1.8 2 0 0 2 2 2 0 F-box-like TMEM51 PF15345.6 ORY77257.1 - 0.072 12.9 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 SKG6 PF08693.10 ORY77257.1 - 0.099 12.1 1.3 0.19 11.2 1.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_1 PF00018.28 ORY77260.1 - 2.6e-08 33.3 0.2 8.6e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORY77260.1 - 4.7e-08 32.8 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY77260.1 - 5.2e-06 26.0 0.0 9.9e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CHAP PF05257.16 ORY77260.1 - 0.053 14.1 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 CHAP domain LON_substr_bdg PF02190.16 ORY77261.1 - 5.1e-18 65.7 0.0 7.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 ORY77261.1 - 4.3e-12 46.0 22.5 5.1e-07 29.7 10.8 2.8 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORY77261.1 - 5.2e-12 45.4 24.3 4.6e-11 42.4 12.1 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY77261.1 - 5.7e-12 45.3 21.1 1.1e-07 31.6 11.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY77261.1 - 1.2e-10 41.1 16.1 2.3e-09 36.9 6.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY77261.1 - 2e-09 37.3 22.7 1.4e-07 31.4 11.0 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 ORY77261.1 - 6.1e-08 32.9 10.8 6.1e-08 32.9 10.8 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 ORY77261.1 - 1.6e-07 31.1 21.0 5.2e-06 26.3 10.6 2.6 2 0 0 2 2 2 2 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY77261.1 - 1.9e-06 27.6 8.1 1.9e-06 27.6 8.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY77261.1 - 1.4e-05 25.1 15.7 0.00023 21.2 4.4 2.4 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_6 PF14835.6 ORY77261.1 - 0.0043 16.9 1.8 0.0043 16.9 1.8 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORY77261.1 - 0.0053 16.5 9.6 0.034 13.9 7.1 2.8 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain U-box PF04564.15 ORY77261.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 ORY77261.1 - 1.3 9.3 16.6 0.025 14.9 8.5 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 ORY77261.1 - 2.3 8.2 8.1 0.41 10.6 2.4 2.1 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-Nse PF11789.8 ORY77261.1 - 6.2 6.7 11.6 1.1 9.1 6.2 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2 PF00096.26 ORY77262.1 - 0.28 11.7 14.8 6.4 7.4 0.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY77262.1 - 5 8.2 14.1 7 7.8 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.25 ORY77263.1 - 7.3e-67 225.5 0.0 9.2e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY77263.1 - 2.7e-40 138.3 0.0 3.5e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY77263.1 - 6.8e-07 28.9 0.0 1.8e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY77263.1 - 0.013 14.9 0.2 0.021 14.2 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY77263.1 - 0.11 12.1 0.1 0.33 10.5 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY77263.1 - 0.16 11.8 0.3 0.91 9.4 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.17 ORY77264.1 - 4.9e-39 134.6 4.1 9.9e-37 127.1 4.1 3.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase HIT PF01230.23 ORY77265.1 - 8.2e-24 84.2 0.8 1e-23 83.9 0.4 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 ORY77265.1 - 1.4e-13 51.3 0.2 1.9e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORY77265.1 - 5.7e-05 23.0 0.1 8.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pirin PF02678.16 ORY77266.1 - 1e-31 109.1 0.4 9.6e-29 99.5 0.1 2.3 2 0 0 2 2 2 2 Pirin Pirin_C PF05726.13 ORY77266.1 - 2.4e-23 82.5 0.0 3.3e-22 78.8 0.1 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 ORY77266.1 - 0.00033 20.3 3.1 0.00061 19.5 0.4 2.5 3 0 0 3 3 3 1 Cupin domain F-box PF00646.33 ORY77267.1 - 0.0032 17.3 0.8 0.0032 17.3 0.8 2.7 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORY77267.1 - 0.023 14.6 0.5 0.023 14.6 0.5 2.7 2 1 0 2 2 2 0 F-box-like LRR_6 PF13516.6 ORY77267.1 - 0.087 12.9 3.5 15 6.0 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 ORY77267.1 - 3.9 8.0 14.8 2.1 8.9 0.9 4.4 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) SBF PF01758.16 ORY77268.1 - 1.5e-46 158.6 11.6 1.5e-46 158.6 11.6 2.0 3 0 0 3 3 3 1 Sodium Bile acid symporter family SBF_like PF13593.6 ORY77268.1 - 2e-08 34.0 16.1 3e-08 33.4 16.1 1.3 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) MRAP PF15183.6 ORY77268.1 - 0.025 14.5 0.1 0.083 12.8 0.1 1.9 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF3464 PF11947.8 ORY77268.1 - 0.28 10.9 5.5 0.33 10.7 1.5 2.6 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 RPAP1_N PF08621.10 ORY77269.1 - 9e-08 31.8 1.6 9e-08 31.8 1.6 2.8 3 0 0 3 3 3 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 ORY77269.1 - 4.3e-06 26.8 0.2 1.3e-05 25.2 0.1 1.9 2 0 0 2 2 2 1 RPAP1-like, C-terminal DRIM PF07539.12 ORY77269.1 - 0.072 11.4 0.1 0.15 10.3 0.1 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis G-patch PF01585.23 ORY77270.1 - 1.6e-05 24.7 0.1 1.6e-05 24.7 0.1 2.2 3 0 0 3 3 3 1 G-patch domain DUF3336 PF11815.8 ORY77272.1 - 5e-44 149.4 0.0 9.1e-44 148.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY77272.1 - 4.2e-19 69.6 0.0 1.3e-18 68.0 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase DUF410 PF04190.13 ORY77273.1 - 1.8e-56 191.8 0.0 2.4e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RCDG1 PF15725.5 ORY77273.1 - 0.0057 17.1 0.7 0.051 14.0 0.5 2.3 2 0 0 2 2 2 1 Renal cancer differentiation gene 1 protein Aldo_ket_red PF00248.21 ORY77275.1 - 5.1e-43 147.3 0.0 7.3e-42 143.6 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L22 PF00237.19 ORY77277.1 - 2.6e-20 72.6 0.0 3.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PI3_PI4_kinase PF00454.27 ORY77279.1 - 5.4e-32 111.6 0.1 1.3e-31 110.3 0.1 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY77279.1 - 7.8e-08 31.9 0.1 2.4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pik1 PF11522.8 ORY77279.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 DUF4135 PF13575.6 ORY77279.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) GCV_T PF01571.21 ORY77556.1 - 1e-71 241.3 0.0 1.2e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORY77556.1 - 8.1e-18 64.1 0.1 2e-17 62.9 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Thioredoxin PF00085.20 ORY77557.1 - 2.8e-24 85.0 0.0 4.5e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY77557.1 - 1.1e-06 28.9 0.0 4.8e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 ORY77557.1 - 3e-06 27.3 0.2 7.1e-06 26.1 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY77557.1 - 3.1e-05 24.4 0.3 0.00032 21.1 0.3 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TPR_6 PF13174.6 ORY77557.1 - 9.1e-05 22.9 0.5 0.019 15.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY77557.1 - 9.3e-05 22.3 5.1 0.0086 16.1 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY77557.1 - 0.00013 21.6 2.5 0.0074 16.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat AhpC-TSA PF00578.21 ORY77557.1 - 0.0003 20.7 0.0 0.00072 19.5 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY77557.1 - 0.00031 20.5 0.2 0.0065 16.2 0.1 2.2 1 1 1 2 2 2 1 Redoxin TPR_17 PF13431.6 ORY77557.1 - 0.00082 19.6 0.2 0.33 11.4 0.1 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY77557.1 - 0.0027 17.6 0.2 0.094 12.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat OST3_OST6 PF04756.13 ORY77557.1 - 0.003 17.0 0.0 0.004 16.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TPR_11 PF13414.6 ORY77557.1 - 0.0067 16.1 0.1 0.024 14.3 0.1 2.0 1 0 0 1 1 1 1 TPR repeat Thioredoxin_9 PF14595.6 ORY77557.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TPR_14 PF13428.6 ORY77557.1 - 0.011 16.4 4.3 0.19 12.7 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY77557.1 - 0.012 16.1 0.8 0.074 13.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY77557.1 - 0.027 14.7 0.7 18 5.9 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY77557.1 - 0.034 14.8 1.0 0.24 12.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TraF PF13728.6 ORY77557.1 - 0.092 12.5 0.9 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein zf-MYND PF01753.18 ORY77558.1 - 5.7e-09 35.9 14.5 8.9e-09 35.3 14.5 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY77558.1 - 0.27 11.6 8.8 0.48 10.8 8.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding RNB PF00773.19 ORY77559.1 - 1.4e-57 195.5 0.0 1.4e-56 192.2 0.0 2.1 1 1 0 1 1 1 1 RNB domain Kelch_4 PF13418.6 ORY77560.1 - 3.5e-11 42.9 17.2 5.9e-08 32.6 0.2 5.5 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY77560.1 - 4.3e-06 26.6 10.7 0.046 13.7 0.0 5.7 7 0 0 7 7 7 2 Kelch motif Kelch_2 PF07646.15 ORY77560.1 - 1.7e-05 24.6 2.3 0.00013 21.8 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 ORY77560.1 - 0.0019 18.4 0.1 0.0019 18.4 0.1 4.9 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY77560.1 - 0.031 14.6 10.1 2.5 8.5 0.1 5.1 4 1 1 5 5 5 0 Kelch motif Kelch_1 PF01344.25 ORY77560.1 - 0.039 13.6 10.7 0.053 13.1 0.1 3.8 3 1 0 3 3 3 0 Kelch motif MscS_porin PF12795.7 ORY77561.1 - 0.22 11.0 1.3 0.34 10.4 1.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DIOX_N PF14226.6 ORY77562.1 - 5.7e-16 59.3 0.0 9.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY77562.1 - 8.9e-14 51.8 0.0 1.5e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_trans_1_3 PF13528.6 ORY77563.1 - 0.0026 17.1 0.0 0.058 12.6 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 1 Glyco_transf_4 PF13439.6 ORY77563.1 - 0.044 13.8 0.0 0.2 11.7 0.0 1.9 1 1 0 1 1 1 0 Glycosyltransferase Family 4 ACBP PF00887.19 ORY77564.1 - 1.7e-27 95.4 0.1 2.1e-27 95.1 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Peptidase_M20 PF01546.28 ORY77565.1 - 3e-32 112.0 0.0 4.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY77565.1 - 1.2e-09 38.1 0.0 3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain PH PF00169.29 ORY77567.1 - 1.4e-34 118.7 2.3 3.9e-19 69.1 0.1 3.1 2 1 0 2 2 2 2 PH domain PH_3 PF14593.6 ORY77567.1 - 5.4e-15 55.4 0.5 6e-07 29.5 0.1 3.2 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 ORY77567.1 - 2.1e-11 44.2 9.0 0.00015 22.1 0.2 3.8 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 ORY77567.1 - 3.3e-11 43.3 0.3 2.8e-06 27.5 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.7 ORY77567.1 - 0.0009 19.4 0.0 0.92 9.6 0.0 2.6 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_13 PF16652.5 ORY77567.1 - 0.0011 18.7 0.2 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 ORY77567.1 - 0.014 15.2 0.2 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 ORY77567.1 - 0.016 15.6 0.4 1.2 9.5 0.3 3.3 3 1 0 3 3 3 0 Pleckstrin homology domain zf-MYND PF01753.18 ORY77568.1 - 9.6e-10 38.4 9.7 1.8e-09 37.6 9.7 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY77568.1 - 0.079 13.3 4.5 0.17 12.2 4.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Gpi16 PF04113.14 ORY77569.1 - 5.1e-107 358.6 0.0 1.5e-105 353.8 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Pkinase PF00069.25 ORY77570.1 - 1.3e-26 93.5 0.0 1.4e-24 86.9 0.0 2.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY77570.1 - 5.3e-14 52.1 0.0 9.1e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY77570.1 - 0.00013 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY77570.1 - 0.0072 15.1 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY77570.1 - 0.033 14.1 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family NDK PF00334.19 ORY77571.1 - 5.8e-35 120.2 0.0 6.5e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase O-FucT PF10250.9 ORY77572.1 - 0.0026 17.5 0.0 0.094 12.4 0.0 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RNB PF00773.19 ORY77573.1 - 7.9e-57 193.0 0.0 8.9e-56 189.6 0.0 2.1 1 1 0 1 1 1 1 RNB domain zf-MYND PF01753.18 ORY77574.1 - 4.2e-10 39.5 10.1 7.5e-10 38.7 10.1 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY77574.1 - 0.16 12.3 8.5 0.44 10.9 8.5 1.8 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HhH-GPD PF00730.25 ORY77575.1 - 1.1e-09 38.7 0.0 1.9e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PV-1 PF06637.11 ORY77576.1 - 2.2 7.0 8.3 3.4 6.4 8.3 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) O-FucT PF10250.9 ORY77577.1 - 6.3e-17 62.3 0.0 1.6e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Epimerase PF01370.21 ORY77578.1 - 4.2e-14 52.6 0.0 2.7e-13 49.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY77578.1 - 2.4e-11 43.3 0.3 1.4e-09 37.6 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 ORY77578.1 - 4.8e-11 42.2 0.0 1.2e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY77578.1 - 5.5e-10 39.4 0.8 1.1e-09 38.5 0.8 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY77578.1 - 2.8e-07 30.4 0.0 4.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY77578.1 - 4.2e-05 22.8 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.23 ORY77578.1 - 4.4e-05 23.6 0.0 7.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 ORY77578.1 - 4.9e-05 22.9 0.2 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY77578.1 - 0.0008 19.7 0.1 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ORY77578.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 ORY77578.1 - 0.0018 18.7 0.0 0.0038 17.7 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.15 ORY77578.1 - 0.013 15.3 0.5 0.022 14.6 0.5 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Aldo_ket_red PF00248.21 ORY77579.1 - 4.8e-48 163.9 0.0 1.8e-46 158.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF3251 PF11622.8 ORY77579.1 - 0.089 12.4 0.0 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) zf-C2H2 PF00096.26 ORY77580.1 - 5.6e-22 76.9 27.0 2.8e-06 27.5 0.6 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY77580.1 - 3.4e-20 71.5 27.0 2.7e-07 30.7 4.2 5.3 4 1 1 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY77580.1 - 1.2e-12 47.5 25.0 0.0012 19.5 7.1 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY77580.1 - 1.3e-05 25.4 5.5 0.0033 17.7 0.8 2.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-TRAF PF02176.18 ORY77580.1 - 4.9e-05 23.9 11.9 0.013 16.2 0.5 3.1 2 1 1 3 3 3 3 TRAF-type zinc finger FOXP-CC PF16159.5 ORY77580.1 - 0.00016 22.2 11.5 0.12 13.1 0.1 4.0 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY77580.1 - 0.019 15.2 6.4 4 7.8 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORY77580.1 - 0.054 13.3 0.3 0.054 13.3 0.3 4.9 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-CGNR PF11706.8 ORY77580.1 - 0.071 13.0 13.8 0.52 10.2 0.4 4.2 4 0 0 4 4 4 0 CGNR zinc finger DUF448 PF04296.13 ORY77580.1 - 0.088 12.7 0.2 15 5.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF448) zf-C2H2_aberr PF17017.5 ORY77580.1 - 0.19 11.9 6.8 8.5 6.5 4.0 2.9 2 2 1 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 ORY77580.1 - 0.3 11.5 9.4 15 6.1 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Sugar_tr PF00083.24 ORY77581.1 - 7.1e-43 147.1 33.2 5.7e-41 140.8 33.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY77581.1 - 1.7e-15 56.8 59.7 4.7e-13 48.8 35.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1634 PF07843.11 ORY77581.1 - 0.64 10.1 8.3 0.11 12.6 0.5 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1634) MMM1 PF10296.9 ORY77582.1 - 4e-16 59.0 0.1 4.4e-10 39.1 0.0 2.9 3 0 0 3 3 3 3 Maintenance of mitochondrial morphology protein 1 FmdA_AmdA PF03069.15 ORY77583.1 - 7.3e-160 531.9 0.0 8.5e-160 531.7 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family RMI1_N PF08585.12 ORY77584.1 - 2.3e-21 76.6 2.4 4e-21 75.8 2.4 1.4 1 0 0 1 1 1 1 RecQ mediated genome instability protein DnaJ PF00226.31 ORY77586.1 - 9.3e-11 41.7 0.1 2e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain MBOAT PF03062.19 ORY77588.1 - 1.1e-53 182.8 9.7 1.6e-53 182.3 9.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 ORY77588.1 - 0.29 11.8 1.9 0.64 10.7 1.9 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ada_Zn_binding PF02805.16 ORY77589.1 - 5.9e-29 99.9 5.2 9.2e-29 99.3 5.2 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 ORY77589.1 - 3.3e-06 27.0 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 ORY77589.1 - 5.5e-05 23.4 0.0 9.6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_53 PF18606.1 ORY77589.1 - 0.07 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain Ofd1_CTDD PF10637.9 ORY77590.1 - 9.4e-64 215.2 0.0 6.1e-60 202.7 0.0 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORY77590.1 - 3.7e-27 94.8 0.0 8.8e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORY77590.1 - 3.5e-13 50.3 0.0 8.7e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF4527 PF15030.6 ORY77590.1 - 0.2 11.0 0.4 0.3 10.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) ACOX PF01756.19 ORY77591.1 - 3.7e-44 150.4 0.0 6.7e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORY77591.1 - 5.6e-25 88.3 1.2 9.1e-25 87.6 1.2 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORY77591.1 - 2.8e-10 40.3 0.0 5.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORY77591.1 - 0.023 14.9 1.1 0.24 11.6 1.1 2.4 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain zf-MYND PF01753.18 ORY77593.1 - 3.5e-10 39.8 9.5 6.5e-10 38.9 9.5 1.4 1 0 0 1 1 1 1 MYND finger Glyco_transf_25 PF01755.17 ORY77595.1 - 3.7e-06 27.0 0.0 0.0096 15.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF4246 PF14033.6 ORY77596.1 - 1.4e-138 462.9 0.0 1.6e-138 462.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) SNF2_N PF00176.23 ORY77597.1 - 7.8e-58 195.9 0.0 1.4e-57 195.0 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY77597.1 - 2.8e-16 59.8 0.0 5.7e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY77597.1 - 3.7e-10 40.1 0.0 8.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY77597.1 - 0.00018 21.3 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Chromo PF00385.24 ORY77597.1 - 0.0005 19.9 3.1 0.07 13.1 0.6 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ERCC3_RAD25_C PF16203.5 ORY77597.1 - 0.0034 16.6 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2439 PF10382.9 ORY77597.1 - 0.01 16.2 0.0 2.7 8.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) HDA2-3 PF11496.8 ORY77597.1 - 0.082 12.1 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 TFIIE-A_C PF11521.8 ORY77597.1 - 2.8 8.3 9.3 0.046 14.0 1.5 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Glyco_transf_25 PF01755.17 ORY77601.1 - 9.4e-08 32.2 0.0 0.012 15.5 0.0 2.6 3 0 0 3 3 3 2 Glycosyltransferase family 25 (LPS biosynthesis protein) AAA_33 PF13671.6 ORY77601.1 - 0.12 12.6 0.1 0.26 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.18 ORY77602.1 - 2e-84 283.7 32.1 2.4e-84 283.4 32.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-MYND PF01753.18 ORY77603.1 - 4.3e-10 39.5 11.3 7.7e-10 38.7 11.3 1.4 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 ORY77604.1 - 0.002 18.0 0.1 0.0087 15.9 0.1 2.2 1 1 0 1 1 1 1 F-box-like Prok-E2_A PF14457.6 ORY77604.1 - 0.011 15.3 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic E2 family A LRR_4 PF12799.7 ORY77604.1 - 0.085 13.3 0.3 0.085 13.3 0.3 3.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 ORY77605.1 - 1.9e-09 37.4 12.3 1.9e-09 37.4 12.3 1.7 2 0 0 2 2 2 1 MYND finger DUF2934 PF11154.8 ORY77605.1 - 0.015 15.0 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) DGCR6 PF07324.11 ORY77606.1 - 0.00012 21.7 1.6 0.0067 16.1 0.1 2.1 1 1 1 2 2 2 2 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 ORY77606.1 - 0.0031 17.2 0.4 0.22 11.2 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF2458) zf-MYND PF01753.18 ORY77607.1 - 3.9e-09 36.4 10.9 6.6e-09 35.7 10.9 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY77607.1 - 0.028 14.7 8.4 0.055 13.8 8.4 1.5 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 ORY77607.1 - 0.6 10.3 6.5 1 9.5 6.5 1.3 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SLD5_C PF16922.5 ORY77608.1 - 7.4e-13 48.5 0.0 1.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 ORY77608.1 - 0.0037 17.7 0.3 0.0068 16.9 0.3 1.5 1 0 0 1 1 1 1 GINS complex protein MT-A70 PF05063.14 ORY77609.1 - 2.9e-52 177.1 0.0 4.1e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Peptidase_S9 PF00326.21 ORY77610.1 - 9.4e-05 22.0 0.0 9.7e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9 PF00326.21 ORY77611.1 - 1.3e-32 113.1 0.5 1.9e-32 112.5 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 ORY77611.1 - 2.1e-05 23.6 0.1 3.2e-05 23.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 ORY77611.1 - 0.00057 18.7 1.2 0.0079 14.9 1.2 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ORY77611.1 - 0.0021 17.7 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 ORY77611.1 - 0.0035 16.9 2.7 0.017 14.6 2.7 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase DLH PF01738.18 ORY77611.1 - 0.065 12.8 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Acetyltransf_1 PF00583.25 ORY77612.1 - 2.9e-24 85.6 0.0 6.3e-11 42.5 0.1 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY77612.1 - 6.1e-20 71.4 0.0 7.6e-08 32.3 0.0 3.8 3 1 1 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY77612.1 - 5.4e-17 62.0 0.3 5.3e-07 30.0 0.1 3.6 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY77612.1 - 3.1e-05 24.0 0.0 0.68 10.0 0.0 4.3 5 0 0 5 5 5 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY77612.1 - 0.0019 18.1 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 FR47-like protein DUF3158 PF11358.8 ORY77612.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) Acetyltransf_10 PF13673.7 ORY77613.1 - 9e-07 28.9 0.0 0.00012 22.0 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY77613.1 - 8.3e-06 26.0 0.0 5e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY77613.1 - 0.00029 21.2 0.0 0.00057 20.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY77613.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Phos_pyr_kin PF08543.12 ORY77615.1 - 3.6e-85 285.3 0.0 5.3e-85 284.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 ORY77615.1 - 9.2e-42 143.2 0.0 1.3e-41 142.7 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 ORY77615.1 - 2.2e-06 27.2 0.0 4.7e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HATPase_c PF02518.26 ORY77616.1 - 7.9e-21 74.7 0.0 1.8e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY77616.1 - 2.6e-19 69.4 0.0 5.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY77616.1 - 1.9e-07 31.0 0.7 1.4e-06 28.2 0.2 2.8 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 ORY77616.1 - 0.0038 17.2 0.1 0.0093 16.0 0.1 1.7 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 ORY77616.1 - 0.05 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_11 PF14598.6 ORY77616.1 - 0.057 13.5 0.2 0.25 11.5 0.0 2.1 3 0 0 3 3 3 0 PAS domain PUF PF00806.19 ORY77617.1 - 3.5e-13 48.4 0.0 8.9e-05 22.0 0.0 4.2 5 0 0 5 5 5 3 Pumilio-family RNA binding repeat DUF4633 PF15464.6 ORY77617.1 - 0.064 13.4 0.3 6.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) CFEM PF05730.11 ORY77618.1 - 1.1e-05 25.4 2.1 3.2e-05 23.9 2.1 1.7 1 0 0 1 1 1 1 CFEM domain Pec_lyase PF09492.10 ORY77618.1 - 0.052 12.9 1.4 0.062 12.6 1.4 1.1 1 0 0 1 1 1 0 Pectic acid lyase SLD5_C PF16922.5 ORY77622.1 - 0.012 15.8 0.1 0.021 15.0 0.1 1.4 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus DUF3143 PF11341.8 ORY77622.1 - 0.034 14.5 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Acetyltransf_3 PF13302.7 ORY77623.1 - 8.8e-17 62.1 0.0 3.7e-15 56.8 0.0 2.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C6H2 PF15801.5 ORY77623.1 - 4.6e-07 30.0 11.0 4.6e-07 30.0 11.0 2.5 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding Acetyltransf_8 PF13523.6 ORY77623.1 - 8.3e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY77623.1 - 1.1e-06 28.8 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family zf-MYND PF01753.18 ORY77623.1 - 0.001 19.1 25.2 0.0025 17.9 5.9 2.5 2 0 0 2 2 2 2 MYND finger Zn_Tnp_IS1 PF03811.13 ORY77623.1 - 0.82 9.5 6.1 0.89 9.3 0.2 3.4 3 0 0 3 3 3 0 InsA N-terminal domain HypA PF01155.19 ORY77623.1 - 2.9 7.9 7.2 4.2 7.4 0.3 2.8 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 ORY77623.1 - 10 6.2 14.7 13 5.9 3.1 2.6 2 1 0 2 2 2 0 zinc-ribbons FA_hydroxylase PF04116.13 ORY77625.1 - 1.4e-18 67.5 11.5 1.4e-18 67.5 11.5 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily SLD5_C PF16922.5 ORY77626.1 - 1.2e-12 47.8 0.0 2.6e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 ORY77626.1 - 0.0027 18.2 0.3 0.0048 17.3 0.3 1.5 1 0 0 1 1 1 1 GINS complex protein Trs65 PF12735.7 ORY77627.1 - 6.2e-25 88.3 5.9 8.1e-21 74.7 0.2 3.9 2 2 0 2 2 2 2 TRAPP trafficking subunit Trs65 DGCR6 PF07324.11 ORY77629.1 - 9.2e-05 22.1 0.9 0.0067 16.1 0.0 2.1 1 1 1 2 2 2 2 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.9 ORY77629.1 - 0.0039 16.9 0.3 0.073 12.7 0.3 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2458) zf-MYND PF01753.18 ORY77630.1 - 8.8e-09 35.3 13.0 1.4e-08 34.7 13.0 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY77630.1 - 0.95 9.8 8.4 1.7 9.0 8.4 1.4 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding F-box-like PF12937.7 ORY77631.1 - 0.00053 19.8 1.2 0.0031 17.4 1.2 2.1 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY77631.1 - 0.0099 16.3 1.6 0.042 14.3 0.0 2.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY77631.1 - 0.13 12.1 0.0 9.3 6.3 0.0 2.9 2 0 0 2 2 2 0 F-box domain Malic_M PF03949.15 ORY77633.1 - 5.7e-94 314.2 0.0 8.1e-94 313.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORY77633.1 - 5.7e-56 189.2 0.0 8.9e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain WD40 PF00400.32 ORY77635.1 - 8.9e-11 42.2 9.3 0.00012 22.7 0.2 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY77635.1 - 3.6e-06 27.2 0.0 0.012 15.9 0.0 4.1 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORY77635.1 - 0.07 13.6 0.1 7.4 7.2 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain DUF3678 PF12435.8 ORY77635.1 - 0.43 10.0 7.9 1.5 8.3 7.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Ribosomal_S7e PF01251.18 ORY77636.1 - 2.6e-52 177.3 1.4 3.4e-52 176.9 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e LRR_4 PF12799.7 ORY77637.1 - 0.077 13.4 7.1 1 9.9 1.3 2.8 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Ctf8 PF09696.10 ORY77639.1 - 3e-15 56.8 0.4 2.9e-14 53.6 0.4 2.2 1 1 0 1 1 1 1 Ctf8 Tau95_N PF17682.1 ORY77639.1 - 0.089 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Tau95 Triple barrel domain Thioredoxin PF00085.20 ORY77641.1 - 6.4e-13 48.6 0.0 7e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Shadoo PF14999.6 ORY77642.1 - 0.008 16.3 0.5 0.008 16.3 0.5 2.1 2 0 0 2 2 2 1 Shadow of prion protein, neuroprotective MARVEL PF01284.23 ORY77642.1 - 0.092 12.8 10.4 0.66 10.0 10.4 2.0 1 1 0 1 1 1 0 Membrane-associating domain NUP PF06516.11 ORY77643.1 - 2.5e-131 437.6 0.2 2.9e-131 437.4 0.2 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) dCMP_cyt_deam_1 PF00383.23 ORY77645.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Aldedh PF00171.22 ORY77646.1 - 1.3e-168 561.3 0.2 1.5e-168 561.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY77646.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Thioredoxin PF00085.20 ORY77647.1 - 7.8e-13 48.3 0.0 8.9e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin zf-MYND PF01753.18 ORY77648.1 - 2.8e-07 30.5 10.3 2.8e-07 30.5 10.3 1.9 2 0 0 2 2 2 1 MYND finger GMC_oxred_N PF00732.19 ORY77649.1 - 1.4e-54 185.5 0.0 1.7e-27 96.6 0.0 2.1 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY77649.1 - 1.2e-39 136.1 0.0 1.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY77649.1 - 1.3e-05 24.4 0.2 1.9e-05 23.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY77649.1 - 2.1e-05 23.8 0.1 0.077 12.1 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY77649.1 - 0.0022 17.3 0.1 0.074 12.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY77649.1 - 0.0044 17.2 0.1 0.016 15.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY77649.1 - 0.0048 16.5 0.2 0.03 13.9 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY77649.1 - 0.041 13.1 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Aminotran_1_2 PF00155.21 ORY77650.1 - 1.4e-37 129.7 0.0 2.1e-37 129.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 ORY77651.1 - 3.8e-37 127.9 0.0 6.4e-21 74.5 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 ORY77651.1 - 4.5e-16 59.3 0.0 8.9e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain HEAT_2 PF13646.6 ORY77652.1 - 2.8e-06 27.6 8.8 0.16 12.4 0.0 6.3 5 1 1 6 6 6 4 HEAT repeats Adaptin_N PF01602.20 ORY77652.1 - 0.00039 19.1 3.6 0.007 15.0 0.1 3.8 4 1 0 4 4 4 1 Adaptin N terminal region HEAT PF02985.22 ORY77652.1 - 0.0069 16.6 12.9 7.1 7.2 0.0 7.4 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 ORY77652.1 - 0.15 12.6 16.7 3.1 8.4 0.1 6.7 6 0 0 6 6 6 0 HEAT-like repeat Lon_C PF05362.13 ORY77652.1 - 0.18 11.3 0.1 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain Pkinase PF00069.25 ORY77653.1 - 3.1e-40 138.2 0.0 3.2e-23 82.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY77653.1 - 2.2e-19 69.8 0.0 2.1e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY77653.1 - 3.6e-06 26.5 0.0 0.0037 16.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY77653.1 - 0.059 13.3 0.0 0.31 10.9 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-MYND PF01753.18 ORY77654.1 - 2.1e-09 37.3 9.7 4.2e-09 36.3 9.7 1.5 1 0 0 1 1 1 1 MYND finger VATC PF18716.1 ORY77654.1 - 6.5 6.7 12.3 0.2 11.5 4.6 2.3 2 0 0 2 2 2 0 Vms1-associating treble clef domain SWIB PF02201.18 ORY77656.1 - 2.9e-19 68.7 0.0 9.5e-19 67.1 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain TFIIA PF03153.13 ORY77656.1 - 3.4 7.6 23.0 0.098 12.6 16.4 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_3 PF13920.6 ORY77657.1 - 2.1e-09 37.1 13.5 3.2e-09 36.5 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY77657.1 - 0.064 13.1 12.5 0.11 12.4 12.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 YL1 PF05764.13 ORY77657.1 - 0.57 10.3 4.3 0.88 9.6 4.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF2937 PF11157.8 ORY77658.1 - 0.18 11.5 1.6 0.44 10.2 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) APG6_N PF17675.1 ORY77658.1 - 2.6 8.6 8.0 5.1 7.6 8.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Phage_integrase PF00589.22 ORY77659.1 - 9.5e-05 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family Phage_int_SAM_3 PF14659.6 ORY77659.1 - 0.074 13.3 0.9 0.19 12.0 0.9 1.7 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain CorA PF01544.18 ORY77983.1 - 6.8e-06 25.6 1.4 1.6e-05 24.4 1.4 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Phage_holin_3_6 PF07332.11 ORY77983.1 - 0.066 13.3 1.5 0.18 11.8 1.5 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Fungal_trans PF04082.18 ORY77984.1 - 1.1e-26 93.5 0.1 1.6e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ORY77984.1 - 3.3e-06 27.2 14.1 0.00027 21.2 0.4 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY77984.1 - 0.00013 22.5 8.1 0.11 13.5 2.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY77984.1 - 0.057 13.3 4.6 0.55 10.2 0.9 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 ORY77984.1 - 0.19 12.0 0.4 0.87 9.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Transp_cyt_pur PF02133.15 ORY77985.1 - 6.1e-87 292.2 38.4 8.7e-87 291.7 38.4 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NDUF_B12 PF08122.12 ORY77985.1 - 0.89 9.7 3.2 9.2 6.4 0.5 3.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Aldo_ket_red PF00248.21 ORY77986.1 - 4.1e-45 154.2 0.0 5.8e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.6 ORY77987.1 - 2.9e-26 92.5 0.0 4.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY77987.1 - 1.6e-16 60.6 0.0 2.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF917 PF06032.12 ORY77988.1 - 5.5e-115 383.9 0.2 9.6e-115 383.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 ORY77988.1 - 4.2e-24 85.3 9.7 5.2e-23 81.7 0.6 3.2 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY77988.1 - 9.5e-24 84.1 0.0 2.1e-22 79.7 0.0 3.0 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 ORY77988.1 - 2e-07 30.0 0.6 0.0012 17.5 0.1 2.3 2 0 0 2 2 2 2 MutL protein StbA PF06406.11 ORY77988.1 - 0.03 13.6 1.1 4.8 6.3 0.0 3.1 3 0 0 3 3 3 0 StbA protein BcrAD_BadFG PF01869.20 ORY77988.1 - 0.054 13.0 0.0 0.054 13.0 0.0 2.4 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family HIP1_clath_bdg PF16515.5 ORY77989.1 - 0.0025 18.4 0.5 0.0025 18.4 0.5 1.5 2 0 0 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM76 PF16046.5 ORY77989.1 - 0.028 13.8 0.1 0.037 13.4 0.1 1.1 1 0 0 1 1 1 0 FAM76 protein RRM_1 PF00076.22 ORY77991.1 - 3e-06 26.9 0.0 0.00069 19.4 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIB PF00382.19 ORY77992.1 - 2.4e-38 130.0 0.1 1e-20 73.5 0.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ORY77992.1 - 4.3e-13 48.5 1.2 6.7e-13 47.9 1.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 ORY77992.1 - 0.0057 16.7 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF3679 PF12438.8 ORY77992.1 - 0.04 13.6 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3679) zinc-ribbons_6 PF07191.12 ORY77992.1 - 0.15 12.1 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbons CHD5 PF04420.14 ORY77993.1 - 1.9e-51 174.1 0.0 2.3e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 CHD5-like protein DUF1729 PF08354.10 ORY77993.1 - 0.33 9.8 1.3 0.35 9.7 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) F-box-like PF12937.7 ORY77994.1 - 0.0004 20.2 2.8 0.0021 17.9 2.8 2.2 1 1 0 1 1 1 1 F-box-like PP2C PF00481.21 ORY77995.1 - 3.8e-43 148.0 0.0 3.6e-41 141.5 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY77995.1 - 7.5e-05 22.5 0.0 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 ORY77995.1 - 0.026 14.4 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) LSM PF01423.22 ORY77996.1 - 5.2e-19 67.7 0.1 5.9e-19 67.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain HA2 PF04408.23 ORY77997.1 - 3.3e-24 85.3 0.0 7.7e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY77997.1 - 1.3e-19 70.3 0.0 5.4e-19 68.3 0.0 2.1 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY77997.1 - 6e-12 45.9 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY77997.1 - 4.1e-08 33.2 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY77997.1 - 7.3e-06 26.3 0.0 1.9e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY77997.1 - 0.0002 20.5 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 ORY77997.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ORY77997.1 - 0.0022 17.7 0.1 0.01 15.5 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 ORY77997.1 - 0.0032 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORY77997.1 - 0.096 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 ORY77997.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 ORY77997.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.16 ORY77997.1 - 0.16 11.4 0.2 0.61 9.5 0.0 2.0 3 0 0 3 3 3 0 PhoH-like protein Fungal_trans PF04082.18 ORY77998.1 - 4.4e-22 78.4 0.0 1.3e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY77998.1 - 1.5e-07 31.4 9.2 3.6e-07 30.2 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PGM_PMM_I PF02878.16 ORY77999.1 - 7.1e-17 61.4 0.4 5.2e-07 29.4 0.0 3.1 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 ORY77999.1 - 3.9e-10 39.8 0.3 8.7e-10 38.6 0.3 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 ORY77999.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III RRP36 PF06102.12 ORY78001.1 - 1.1e-34 119.8 31.6 1.1e-34 119.8 31.6 2.7 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 PRONE PF03759.13 ORY78001.1 - 0.0047 15.8 5.3 0.0069 15.2 5.3 1.2 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) ANAPC_CDC26 PF10471.9 ORY78002.1 - 0.79 10.6 4.2 2.6 9.0 4.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF5633 PF18656.1 ORY78004.1 - 7.3 6.6 5.2 25 4.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Sec34 PF04136.15 ORY78005.1 - 6.9e-50 168.8 3.2 6.9e-50 168.8 3.2 2.3 3 0 0 3 3 3 1 Sec34-like family FlgN PF05130.12 ORY78005.1 - 0.048 14.2 3.6 0.2 12.1 3.6 2.1 1 0 0 1 1 1 0 FlgN protein DUF629 PF04780.12 ORY78006.1 - 0.055 12.0 0.2 0.067 11.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) FOXP-CC PF16159.5 ORY78006.1 - 0.055 14.1 0.1 0.073 13.7 0.1 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY78006.1 - 0.21 12.5 1.1 0.35 11.8 1.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger GatB_N PF02934.15 ORY78007.1 - 2.1e-98 329.1 0.0 2.7e-98 328.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ORY78007.1 - 7.1e-29 100.6 0.0 1.1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 GatB domain bVLRF1 PF18826.1 ORY78008.1 - 1.5e-61 206.6 0.0 2.4e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor DUF2826 PF11442.8 ORY78008.1 - 0.0016 18.3 0.1 0.35 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2826) Ank_5 PF13857.6 ORY78008.1 - 0.0016 18.7 0.0 0.0061 16.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY78008.1 - 0.16 12.6 0.0 0.48 11.0 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) AF-4 PF05110.13 ORY78008.1 - 0.42 8.6 21.5 0.018 13.2 8.1 2.2 2 0 0 2 2 2 0 AF-4 proto-oncoprotein Olduvai PF06758.13 ORY78008.1 - 2.8 8.3 6.5 8.5 6.7 0.0 3.4 3 0 0 3 3 3 0 Olduvai domain LRR_4 PF12799.7 ORY78009.1 - 0.089 13.3 10.0 0.62 10.6 0.2 4.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Mannosyl_trans2 PF04188.13 ORY78010.1 - 1.1e-62 212.8 0.3 1.4e-62 212.5 0.3 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) PMT PF02366.18 ORY78010.1 - 0.0038 16.9 0.9 0.0038 16.9 0.9 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase ANAPC4_WD40 PF12894.7 ORY78011.1 - 9.8e-11 41.8 0.1 0.0057 16.9 0.1 4.7 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY78011.1 - 3.6e-10 40.3 2.2 4.8e-05 24.0 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 ORY78011.1 - 0.0042 17.0 0.0 6.6 6.5 0.0 3.7 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A DPPIV_N PF00930.21 ORY78011.1 - 0.078 11.7 0.0 0.92 8.2 0.0 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 ORY78011.1 - 0.29 10.9 1.5 2.1 8.1 0.0 2.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature IKI3 PF04762.12 ORY78011.1 - 0.35 8.8 0.1 19 3.1 0.0 2.8 2 1 1 3 3 3 0 IKI3 family Kinesin PF00225.23 ORY78012.1 - 1e-102 343.5 0.0 1.4e-102 343.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY78012.1 - 1.8e-20 73.4 0.0 5.5e-20 71.8 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding PIF1 PF05970.14 ORY78012.1 - 0.095 11.9 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase Erp_C PF06780.11 ORY78012.1 - 0.15 12.1 1.2 20 5.2 0.6 2.6 2 1 0 2 2 2 0 Erp protein C-terminus BST2 PF16716.5 ORY78013.1 - 0.25 12.0 2.0 21 5.8 0.0 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 AAA_33 PF13671.6 ORY78016.1 - 8.4e-14 51.9 0.0 4.8e-11 43.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.11 ORY78016.1 - 3e-06 27.4 0.0 4.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 ORY78016.1 - 0.00015 22.3 0.0 0.00044 20.8 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY78016.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY78016.1 - 0.012 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 ORY78016.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 ORY78016.1 - 0.036 13.8 0.1 0.61 9.9 0.1 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain dNK PF01712.19 ORY78016.1 - 0.042 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase KTI12 PF08433.10 ORY78016.1 - 0.048 13.1 0.0 0.99 8.8 0.1 2.1 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 ORY78016.1 - 0.063 13.6 0.0 0.18 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 ORY78016.1 - 0.087 12.7 0.2 0.51 10.2 0.1 1.9 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.15 ORY78016.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_PrkA PF08298.11 ORY78016.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain T2SSE PF00437.20 ORY78016.1 - 0.24 10.4 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribonuc_red_sm PF00268.21 ORY78017.1 - 1.1e-114 382.7 0.0 1.3e-114 382.4 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PQ-loop PF04193.14 ORY78018.1 - 5.6e-25 86.9 3.1 6.7e-18 64.2 0.2 2.9 3 0 0 3 3 3 2 PQ loop repeat Flavi_NS4A PF01350.17 ORY78018.1 - 0.19 11.7 1.6 0.32 10.9 0.7 1.9 1 1 0 1 1 1 0 Flavivirus non-structural protein NS4A Wzy_C_2 PF11846.8 ORY78018.1 - 0.28 11.1 10.8 0.13 12.1 0.6 2.6 2 1 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal CSN8_PSD8_EIF3K PF10075.9 ORY78019.1 - 6.6e-13 48.9 0.0 3.1e-12 46.7 0.0 2.2 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family zf-CCCH PF00642.24 ORY78020.1 - 1.3e-21 75.9 32.1 2.9e-05 23.9 1.2 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY78020.1 - 2.9e-19 68.4 37.5 8.5e-06 25.7 3.4 5.8 6 0 0 6 6 6 5 Zinc finger domain Torus PF16131.5 ORY78020.1 - 2.3e-10 41.1 21.9 0.0021 18.8 1.1 5.2 2 1 3 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 ORY78020.1 - 2e-08 33.8 30.6 0.00017 21.3 0.6 5.6 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCHC PF00098.23 ORY78020.1 - 3.9e-06 26.7 8.6 4.1e-06 26.6 4.8 2.8 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_3 PF15663.5 ORY78020.1 - 0.00033 20.8 18.3 0.082 13.1 4.4 4.3 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCHC_3 PF13917.6 ORY78020.1 - 0.0042 17.0 0.3 0.014 15.4 0.3 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ORY78020.1 - 0.0056 16.5 4.5 0.0056 16.5 4.5 2.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 ORY78020.1 - 0.0084 16.6 43.6 0.062 13.8 2.7 6.3 6 0 0 6 6 6 3 RNA-binding, Nab2-type zinc finger Syja_N PF02383.18 ORY78021.1 - 2.3e-83 280.2 0.1 3.1e-83 279.8 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain F-box-like PF12937.7 ORY78022.1 - 0.0092 15.9 1.6 0.15 11.9 1.6 2.5 1 1 0 1 1 1 1 F-box-like Metallophos PF00149.28 ORY78023.1 - 4.4e-36 125.3 0.0 7.3e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY78023.1 - 2.9e-18 66.0 0.0 5.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain RRM_1 PF00076.22 ORY78024.1 - 0.078 12.8 0.0 0.46 10.3 0.0 2.4 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 ORY78025.1 - 0.047 14.3 0.0 0.094 13.3 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RNase_HII PF01351.18 ORY78027.1 - 2e-50 171.4 0.0 2.7e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII Glyco_transf_22 PF03901.17 ORY78028.1 - 4.3e-86 289.7 20.2 3.5e-70 237.3 14.1 2.0 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 ORY78028.1 - 7.1 6.8 14.7 1.5 9.0 8.2 2.9 2 2 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase WAC_Acf1_DNA_bd PF10537.9 ORY78029.1 - 2.9e-33 114.4 2.1 4.5e-33 113.8 0.5 2.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 ORY78029.1 - 2.2e-29 101.8 2.2 3.5e-29 101.2 0.2 2.5 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 ORY78029.1 - 4.5e-10 39.7 0.5 7.5e-10 39.0 0.5 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 ORY78029.1 - 0.00035 20.0 0.0 0.00069 19.1 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Kelch_5 PF13854.6 ORY78030.1 - 2e-11 43.6 5.6 0.003 17.5 0.0 5.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 ORY78030.1 - 1.1e-10 41.5 19.5 8.7e-05 22.7 0.1 6.8 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY78030.1 - 1.5e-05 24.5 7.0 0.42 10.2 0.2 5.9 6 1 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 ORY78030.1 - 2e-05 24.7 11.0 1.7 9.0 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 ORY78030.1 - 2.8e-05 24.0 14.8 0.57 10.2 0.1 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY78030.1 - 0.012 15.6 7.6 1.1 9.3 0.1 4.8 5 0 0 5 5 5 0 Kelch motif SKG6 PF08693.10 ORY78030.1 - 0.032 13.7 1.3 0.069 12.6 1.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CcmD PF04995.14 ORY78030.1 - 0.078 13.1 4.8 0.15 12.2 4.8 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) VPDSG-CTERM PF18205.1 ORY78030.1 - 0.27 11.1 7.4 1.1 9.1 7.4 2.1 1 0 0 1 1 1 0 VPDSG-CTERM motif Gram_pos_anchor PF00746.21 ORY78030.1 - 1.4 8.9 3.5 3.8 7.5 3.5 1.8 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Complex1_LYR PF05347.15 ORY78031.1 - 4.2e-12 45.9 0.1 5.5e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 ORY78031.1 - 0.0015 19.1 0.1 0.0021 18.7 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like ICE2 PF08426.10 ORY78032.1 - 3.8e-81 273.3 20.0 9e-81 272.1 20.0 1.5 1 1 0 1 1 1 1 ICE2 DUF996 PF06195.13 ORY78032.1 - 0.074 13.3 3.2 0.11 12.8 0.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF996) zf-LYAR PF08790.11 ORY78033.1 - 1e-14 54.1 5.9 1e-14 54.1 5.9 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 ORY78033.1 - 0.0052 16.3 0.4 0.68 9.6 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger Pol_alpha_B_N PF08418.10 ORY78033.1 - 0.4 10.6 9.6 0.57 10.1 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF4551 PF15087.6 ORY78033.1 - 1.8 7.3 6.7 2.1 7.1 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Spt20 PF12090.8 ORY78033.1 - 2.4 7.7 16.8 5.7 6.5 16.9 1.5 1 1 0 1 1 1 0 Spt20 family Presenilin PF01080.17 ORY78033.1 - 2.6 6.7 6.3 3.4 6.3 6.3 1.2 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.14 ORY78033.1 - 4.4 6.4 8.5 7.5 5.7 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Nucleo_P87 PF07267.11 ORY78033.1 - 6.6 5.4 6.6 7.7 5.2 6.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Coilin_N PF15862.5 ORY78033.1 - 7.8 6.3 16.5 9.4 6.0 0.3 2.2 2 0 0 2 2 2 0 Coilin N-terminus Epimerase PF01370.21 ORY78034.1 - 1.4e-12 47.6 0.0 4.4e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY78034.1 - 3.1e-12 46.1 0.0 5e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY78034.1 - 8e-09 35.0 0.0 2e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY78034.1 - 1e-06 28.4 0.0 1.7e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY78034.1 - 5.3e-05 23.2 0.3 9.1e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ORY78034.1 - 8.8e-05 22.5 0.2 0.00043 20.2 0.2 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORY78034.1 - 0.00043 19.8 0.2 0.0024 17.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ORY78034.1 - 0.00058 19.1 0.0 0.00084 18.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY78034.1 - 0.032 13.3 0.3 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 ORY78034.1 - 0.042 13.4 0.1 0.076 12.6 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family XLF PF09302.11 ORY78035.1 - 0.0088 16.2 0.6 0.016 15.4 0.4 1.5 1 1 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component bZIP_1 PF00170.21 ORY78035.1 - 0.0088 16.1 12.0 0.013 15.5 12.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor DUF1682 PF07946.14 ORY78035.1 - 0.012 14.8 1.6 0.015 14.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FAM76 PF16046.5 ORY78035.1 - 0.22 10.9 2.7 0.27 10.5 2.7 1.1 1 0 0 1 1 1 0 FAM76 protein Med9 PF07544.13 ORY78035.1 - 0.62 10.2 9.9 0.33 11.1 6.1 2.1 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf-MYND PF01753.18 ORY78036.1 - 2.8e-09 36.9 9.3 3.8e-09 36.5 9.3 1.2 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY78036.1 - 0.043 13.7 2.5 0.065 13.1 2.5 1.3 1 0 0 1 1 1 0 HIT zinc finger RecR PF02132.15 ORY78036.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 RecR protein bZIP_2 PF07716.15 ORY78037.1 - 6.7e-06 26.1 7.9 1.5e-05 25.0 7.9 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY78037.1 - 0.025 14.7 5.8 0.051 13.7 5.8 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF1151 PF06625.11 ORY78037.1 - 0.046 13.7 1.4 0.092 12.7 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Med9 PF07544.13 ORY78037.1 - 0.1 12.7 0.7 0.22 11.6 0.7 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 5_nucleotid_C PF02872.18 ORY78038.1 - 0.01 16.0 0.0 0.036 14.3 0.0 1.7 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain VPS28 PF03997.12 ORY78039.1 - 1.1e-72 243.7 0.1 1.3e-72 243.5 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Flu_NS2 PF00601.19 ORY78039.1 - 0.037 14.3 0.1 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) IF4E PF01652.18 ORY78040.1 - 7.5e-53 178.6 0.1 9.6e-53 178.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mito_carr PF00153.27 ORY78041.1 - 8e-55 182.8 0.4 2.3e-18 65.9 0.0 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 ORY78041.1 - 0.1 11.7 0.4 2.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease EVE PF01878.18 ORY78042.1 - 2.8e-37 127.9 0.0 4.4e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 EVE domain BING4CT PF08149.11 ORY78043.1 - 4.4e-39 132.2 0.0 4.8e-36 122.4 0.0 3.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 ORY78043.1 - 5.2e-07 30.3 0.2 0.0062 17.4 0.0 5.3 5 1 1 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY78043.1 - 1.5e-06 28.4 0.0 0.79 10.1 0.0 5.0 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1852 PF08908.11 ORY78043.1 - 0.0014 17.7 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1852) SLAIN PF15301.6 ORY78043.1 - 0.049 12.9 2.8 0.087 12.1 2.8 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family CDC45 PF02724.14 ORY78043.1 - 0.31 9.3 17.1 0.46 8.7 17.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 ORY78043.1 - 1.9 8.9 14.5 6 7.3 14.5 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 ORY78043.1 - 5.4 5.4 7.2 8.2 4.8 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 bZIP_1 PF00170.21 ORY78044.1 - 0.0004 20.4 0.7 0.00082 19.4 0.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY78044.1 - 0.0017 18.4 3.4 0.0017 18.4 3.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper DUF3903 PF13043.6 ORY78045.1 - 0.14 11.9 0.5 0.45 10.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3903) CAP_N PF01213.19 ORY78045.1 - 2.5 7.5 8.1 2.4 7.5 8.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 ORY78045.1 - 5.3 7.1 7.4 5.6 7.0 7.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 ORY78045.1 - 5.7 7.0 11.3 6.9 6.7 11.3 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 bZIP_1 PF00170.21 ORY78046.1 - 9.5e-11 41.6 11.4 9.5e-11 41.6 11.4 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY78046.1 - 4.9e-09 36.1 13.1 4.9e-09 36.1 13.1 1.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF737 PF05300.11 ORY78046.1 - 0.0014 19.0 5.2 0.0021 18.5 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) HOOK PF05622.12 ORY78046.1 - 0.009 14.2 3.7 0.011 13.9 3.7 1.1 1 0 0 1 1 1 1 HOOK protein bZIP_Maf PF03131.17 ORY78046.1 - 0.0091 16.5 8.0 0.0091 16.5 8.0 2.2 2 1 1 3 3 3 1 bZIP Maf transcription factor TSC22 PF01166.18 ORY78046.1 - 0.016 15.5 1.4 0.034 14.5 1.4 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family YabA PF06156.13 ORY78046.1 - 0.033 14.8 1.0 0.067 13.8 1.0 1.6 1 0 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 ORY78046.1 - 0.15 11.4 9.9 0.18 11.1 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 ORY78046.1 - 0.19 11.5 6.6 0.11 12.3 4.6 1.6 2 0 0 2 2 2 0 Septum formation initiator CDC27 PF09507.10 ORY78046.1 - 0.24 10.8 8.5 0.3 10.4 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HAUS6_N PF14661.6 ORY78046.1 - 0.32 10.6 5.1 0.47 10.0 5.0 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus F-box-like PF12937.7 ORY78048.1 - 0.0016 18.3 1.1 0.0016 18.3 1.1 2.9 2 1 0 2 2 2 1 F-box-like CUE PF02845.16 ORY78048.1 - 0.11 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 CUE domain LRR_4 PF12799.7 ORY78048.1 - 0.52 10.8 2.7 9 6.9 0.2 3.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 ORY78049.1 - 2.3e-06 27.6 2.0 4.5e-06 26.7 2.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY78049.1 - 0.0002 21.4 5.0 0.0002 21.4 5.0 1.9 2 0 0 2 2 2 1 Basic region leucine zipper DUF4748 PF15932.5 ORY78049.1 - 7.1 6.5 6.3 2.2 8.1 3.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) zf-MYND PF01753.18 ORY78050.1 - 2.4e-10 40.3 12.0 4.2e-10 39.6 12.0 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY78050.1 - 1.1 9.5 7.0 2.1 8.5 7.0 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Mito_carr PF00153.27 ORY78051.1 - 2.4e-05 24.2 0.2 0.62 10.0 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein RRM_1 PF00076.22 ORY78052.1 - 3.6e-17 61.9 0.0 5.4e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY78052.1 - 1.8e-06 27.9 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif LigD_N PF13298.6 ORY78053.1 - 2.1e-11 44.1 0.1 5.6e-11 42.7 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) O-FucT PF10250.9 ORY78054.1 - 7.8e-05 22.5 0.0 0.026 14.2 0.0 2.5 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase F-box-like PF12937.7 ORY78055.1 - 0.0033 17.3 0.1 0.065 13.1 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY78055.1 - 0.05 14.1 1.7 14 6.3 0.5 4.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LigD_N PF13298.6 ORY78056.1 - 0.0012 19.1 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) FAM177 PF14774.6 ORY78056.1 - 0.051 14.0 0.3 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 FAM177 family HTH_32 PF13565.6 ORY78056.1 - 0.052 14.2 0.4 1.1 9.9 0.2 2.7 2 0 0 2 2 2 0 Homeodomain-like domain bZIP_1 PF00170.21 ORY78057.1 - 2.2e-10 40.5 13.4 2.2e-10 40.5 13.4 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY78057.1 - 4.9e-10 39.3 14.5 4.9e-10 39.3 14.5 1.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF737 PF05300.11 ORY78057.1 - 9.8e-06 26.1 5.8 1.4e-05 25.6 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF737) GAS PF13851.6 ORY78057.1 - 0.0014 18.0 4.7 0.0017 17.7 4.7 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 ORY78057.1 - 0.0016 18.7 1.5 0.0032 17.7 1.5 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_Maf PF03131.17 ORY78057.1 - 0.0087 16.6 9.8 0.0087 16.6 9.8 1.9 1 1 1 2 2 2 1 bZIP Maf transcription factor HOOK PF05622.12 ORY78057.1 - 0.015 13.5 7.0 0.019 13.2 7.0 1.0 1 0 0 1 1 1 0 HOOK protein DivIC PF04977.15 ORY78057.1 - 0.11 12.3 6.6 0.062 13.1 4.6 1.6 2 0 0 2 2 2 0 Septum formation initiator YabA PF06156.13 ORY78057.1 - 0.44 11.2 4.9 0.94 10.1 4.9 1.6 1 1 0 1 1 1 0 Initiation control protein YabA OmpH PF03938.14 ORY78057.1 - 0.5 10.7 6.7 0.63 10.4 6.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.8 ORY78057.1 - 0.95 10.2 14.6 0.86 10.3 13.4 1.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term HAUS6_N PF14661.6 ORY78057.1 - 0.98 9.0 7.2 1.2 8.7 6.8 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus LigD_N PF13298.6 ORY78058.1 - 1.2e-08 35.2 0.8 2.4e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase Ligase (LigD) AI-2E_transport PF01594.16 ORY78059.1 - 0.00016 20.9 2.4 0.00023 20.5 2.4 1.2 1 0 0 1 1 1 1 AI-2E family transporter PGPGW PF09656.10 ORY78059.1 - 0.32 10.6 4.3 7 6.3 0.5 2.6 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) NAD_binding_6 PF08030.12 ORY78060.1 - 5.9e-17 62.2 0.0 9.7e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY78060.1 - 7.2e-17 61.7 13.1 7.2e-17 61.7 13.1 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY78060.1 - 1e-09 38.4 0.0 2.4e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY78060.1 - 0.00031 21.3 0.0 0.12 13.0 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 ORY78060.1 - 0.62 10.7 19.7 1.2 9.8 6.3 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) UPF0182 PF03699.13 ORY78060.1 - 8.7 4.3 8.3 14 3.6 8.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) NAD_binding_6 PF08030.12 ORY78061.1 - 6.7e-20 71.8 0.0 1.5e-19 70.6 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY78061.1 - 3.3e-16 59.5 11.5 3.3e-16 59.5 11.5 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY78061.1 - 8e-09 35.6 0.0 1.8e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY78061.1 - 6.2e-06 26.8 0.0 0.12 13.0 0.0 3.1 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain Bac_export_3 PF01313.19 ORY78061.1 - 0.12 12.3 1.4 0.26 11.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial export proteins, family 3 UPF0182 PF03699.13 ORY78061.1 - 0.36 8.9 3.4 0.59 8.2 3.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) YtpI PF14007.6 ORY78061.1 - 0.59 10.3 5.2 8.1 6.7 1.3 3.2 3 0 0 3 3 3 0 YtpI-like protein 2TM PF13239.6 ORY78061.1 - 0.65 10.3 6.5 0.19 12.1 1.3 2.6 2 0 0 2 2 2 0 2TM domain DUF4405 PF14358.6 ORY78061.1 - 1.1 9.8 12.1 0.051 14.1 1.7 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ribosomal_L6 PF00347.23 ORY78062.1 - 1e-24 87.0 2.3 1.3e-10 41.8 0.2 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 CTD_bind PF04818.13 ORY78063.1 - 2.1e-05 25.3 0.0 4.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2HE PF16278.5 ORY78063.1 - 0.047 14.1 0.2 0.4 11.2 0.1 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SMN PF06003.12 ORY78064.1 - 8.4e-07 28.5 1.0 8.4e-07 28.5 1.0 1.6 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) Tudor_3 PF18115.1 ORY78064.1 - 0.0053 16.6 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain PWWP PF00855.17 ORY78064.1 - 0.0058 17.0 0.4 0.017 15.5 0.4 1.8 1 1 0 1 1 1 1 PWWP domain U79_P34 PF03064.16 ORY78064.1 - 0.017 14.5 3.7 0.021 14.2 3.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 LBR_tudor PF09465.10 ORY78064.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Relaxase PF03432.14 ORY78064.1 - 0.17 11.5 6.0 0.25 10.9 6.0 1.2 1 0 0 1 1 1 0 Relaxase/Mobilisation nuclease domain DUF1325 PF07039.11 ORY78064.1 - 0.17 12.0 5.0 0.25 11.4 2.3 2.1 1 1 1 2 2 2 0 SGF29 tudor-like domain Presenilin PF01080.17 ORY78064.1 - 0.43 9.3 2.2 0.53 9.0 2.2 1.2 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 ORY78064.1 - 0.92 7.9 15.6 1.3 7.4 15.6 1.1 1 0 0 1 1 1 0 Mpp10 protein G0-G1_switch_2 PF15103.6 ORY78064.1 - 2.4 8.6 7.1 45 4.5 6.1 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 Jak1_Phl PF17887.1 ORY78064.1 - 3.2 7.7 7.3 5.4 7.0 7.3 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Connexin PF00029.19 ORY78064.1 - 4.4 7.0 4.0 6 6.6 4.0 1.1 1 0 0 1 1 1 0 Connexin NARP1 PF12569.8 ORY78064.1 - 4.9 5.9 11.9 1.3 7.8 9.2 1.3 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TMA7 PF09072.10 ORY78064.1 - 6.2 7.7 21.0 15 6.5 21.0 1.7 1 1 0 1 1 1 0 Translation machinery associated TMA7 Snf7 PF03357.21 ORY78065.1 - 2.5e-33 115.1 9.0 3.2e-33 114.8 9.0 1.1 1 0 0 1 1 1 1 Snf7 Arf PF00025.21 ORY78066.1 - 1.2e-43 148.6 0.0 1.5e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY78066.1 - 4.3e-12 46.3 0.0 6.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY78066.1 - 9.1e-10 38.4 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY78066.1 - 1.7e-09 37.4 0.0 2.1e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY78066.1 - 2.7e-09 36.7 0.1 3.6e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY78066.1 - 7.5e-09 35.3 0.0 9.6e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY78066.1 - 1.1e-06 28.7 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY78066.1 - 3e-05 23.6 0.1 0.00061 19.4 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY78066.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 ORY78067.1 - 8.2e-79 265.4 1.7 1.7e-78 264.3 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY78067.1 - 0.00021 20.3 0.0 0.00036 19.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY78067.1 - 0.00027 19.6 0.0 0.0005 18.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ORY78067.1 - 0.024 14.0 0.1 0.12 11.7 0.1 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.10 ORY78067.1 - 0.048 14.2 2.2 0.12 12.9 2.2 1.7 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Thiolase_N PF00108.23 ORY78068.1 - 1.2e-89 300.1 3.4 1.7e-89 299.6 3.4 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY78068.1 - 2.3e-42 143.5 1.0 1e-41 141.5 1.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY78068.1 - 0.0001 22.0 1.0 0.0001 22.0 1.0 2.7 2 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Pribosyltran PF00156.27 ORY78069.1 - 3.5e-17 62.4 0.0 4.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 ORY78069.1 - 0.00081 18.9 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase E1_DerP2_DerF2 PF02221.15 ORY78070.1 - 2.4e-26 92.8 0.1 2.9e-26 92.5 0.1 1.0 1 0 0 1 1 1 1 ML domain Mre11_DNA_bind PF04152.14 ORY78071.1 - 5.1e-50 170.1 0.7 5.1e-50 170.1 0.7 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 ORY78071.1 - 8.3e-13 49.3 0.4 1.7e-12 48.3 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY78071.1 - 0.0011 19.2 0.0 0.014 15.6 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 ORY78072.1 - 1.4e-05 24.9 0.1 2.8e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF2012 PF09430.10 ORY78073.1 - 1.5e-14 54.1 0.0 2.6e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) zf-ZPR1 PF03367.13 ORY78074.1 - 1.8e-109 362.6 0.1 1e-54 184.7 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain OrfB_Zn_ribbon PF07282.11 ORY78074.1 - 0.065 13.2 2.4 13 5.8 0.1 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain CRT10 PF08728.10 ORY78074.1 - 0.084 11.0 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 CRT10 DZR PF12773.7 ORY78074.1 - 0.093 12.8 3.5 3 7.9 0.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 ORY78074.1 - 0.18 11.8 1.1 17 5.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.10 ORY78074.1 - 0.57 10.3 5.7 23 5.2 0.2 3.7 3 1 0 3 3 3 0 Zinc ribbon domain DnaJ PF00226.31 ORY78075.1 - 1.8e-09 37.6 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Ubiq-Cytc-red_N PF09165.10 ORY78075.1 - 0.046 14.6 0.4 0.074 13.9 0.4 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Mst1_SARAH PF11629.8 ORY78076.1 - 0.0088 16.1 1.7 0.024 14.7 1.7 1.7 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 AAA_23 PF13476.6 ORY78076.1 - 0.34 11.4 2.0 6.1 7.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain SWI-SNF_Ssr4 PF08549.10 ORY78076.1 - 1.1 7.8 36.0 0.0068 15.1 17.8 3.7 3 1 0 3 3 3 0 Fungal domain of unknown function (DUF1750) Rrn6 PF10214.9 ORY78076.1 - 3.1 6.2 8.6 5.4 5.4 8.6 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4407 PF14362.6 ORY78076.1 - 7.6 5.8 21.2 4.6 6.5 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TPP_enzyme_N PF02776.18 ORY78077.1 - 3.6e-35 121.1 0.1 2.6e-34 118.3 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORY78077.1 - 8.1e-20 71.1 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY78077.1 - 2.6e-13 49.9 0.0 6.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain SRP54 PF00448.22 ORY78077.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Aa_trans PF01490.18 ORY78078.1 - 9.4e-55 186.0 17.9 1.3e-54 185.6 17.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY78078.1 - 1.2 8.1 24.0 0.033 13.2 16.7 1.8 2 1 0 2 2 2 0 Tryptophan/tyrosine permease family zf-MYND PF01753.18 ORY78079.1 - 1.3e-08 34.7 12.5 2.6e-08 33.8 12.5 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY78079.1 - 0.13 12.1 6.8 0.27 11.1 6.8 1.5 1 0 0 1 1 1 0 HIT zinc finger MTP18 PF10558.9 ORY78082.1 - 5.1e-57 192.5 1.7 5.8e-55 185.9 1.7 2.0 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Pro_isomerase PF00160.21 ORY78083.1 - 5.3e-44 150.3 0.0 9.3e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 ORY78083.1 - 5.5e-05 23.2 0.1 0.00024 21.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 ORY78083.1 - 0.0003 20.2 0.5 0.041 13.2 0.0 3.0 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 ORY78083.1 - 0.00082 19.5 0.1 0.046 13.9 0.0 3.0 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.8 ORY78083.1 - 0.0056 16.5 0.1 0.017 14.9 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Leo1 PF04004.13 ORY78084.1 - 2.5e-40 138.0 0.3 2.5e-40 138.0 0.3 2.7 2 1 0 2 2 2 1 Leo1-like protein BUD22 PF09073.10 ORY78084.1 - 0.0015 18.0 17.5 0.0015 18.0 17.5 2.1 2 0 0 2 2 2 1 BUD22 Atx10homo_assoc PF09759.9 ORY78085.1 - 9.7e-21 73.7 0.0 2.3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 ORY78085.1 - 0.008 16.2 3.4 1.8 8.7 0.3 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat WD40 PF00400.32 ORY78086.1 - 9.6e-58 190.8 19.8 3.7e-10 40.2 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY78086.1 - 7e-21 74.3 0.3 1.4e-06 28.5 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY78086.1 - 3.8e-11 42.3 7.6 0.019 13.6 0.1 5.0 1 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY78086.1 - 5.6e-09 36.1 0.1 1.2e-06 28.6 0.0 3.3 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY78086.1 - 6e-08 32.4 0.0 0.00038 19.9 0.0 2.5 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 ORY78086.1 - 7.4e-08 31.7 1.6 0.17 10.8 0.1 4.3 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 ORY78086.1 - 7.3e-07 27.9 0.0 0.00065 18.1 0.0 2.1 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 ORY78086.1 - 0.00068 18.7 0.9 3.4 6.5 0.0 3.2 2 1 1 3 3 3 3 Partner and localizer of BRCA2 WD40 domain Coatomer_WDAD PF04053.14 ORY78086.1 - 0.01 14.9 0.1 2 7.4 0.2 2.2 1 1 0 2 2 2 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 ORY78086.1 - 0.022 13.3 0.6 0.9 8.0 0.0 2.6 1 1 0 3 3 3 0 Cytochrome D1 heme domain IKI3 PF04762.12 ORY78086.1 - 0.039 12.0 0.1 0.098 10.6 0.0 1.8 1 1 0 1 1 1 0 IKI3 family FAP PF07174.11 ORY78086.1 - 1.1 8.6 7.4 0.72 9.3 5.6 1.5 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) PD40 PF07676.12 ORY78086.1 - 1.2 9.2 5.2 0.66 10.0 0.2 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RIO1 PF01163.22 ORY78087.1 - 1.9e-41 141.7 0.0 2.9e-29 102.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 ORY78087.1 - 5.8e-29 100.1 0.0 1.3e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 ORY78087.1 - 1.3e-06 28.5 0.2 0.0091 15.9 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY78087.1 - 1.4e-05 24.6 0.0 0.085 12.2 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family ESSS PF10183.9 ORY78088.1 - 5.5e-10 39.4 0.0 5.8e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DnaJ-X PF14308.6 ORY78089.1 - 5.2e-56 189.4 1.9 5.2e-56 189.4 1.9 2.1 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORY78089.1 - 2.2e-24 85.4 0.3 2.2e-24 85.4 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain F-box-like PF12937.7 ORY78090.1 - 3.6e-09 36.4 0.3 9.4e-09 35.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY78090.1 - 0.00031 20.5 1.1 0.00031 20.5 1.1 2.3 2 1 0 2 2 2 1 F-box domain MyTH4 PF00784.17 ORY78090.1 - 0.14 12.6 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 MyTH4 domain Beta_elim_lyase PF01212.21 ORY78091.1 - 3.2e-75 253.1 0.0 4.4e-75 252.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORY78091.1 - 5.6e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY78091.1 - 0.0014 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY78091.1 - 0.016 13.7 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aldedh PF00171.22 ORY78091.1 - 0.022 13.3 0.0 0.044 12.3 0.0 1.4 1 0 0 1 1 1 0 Aldehyde dehydrogenase family GATase_4 PF13230.6 ORY78092.1 - 1.2e-18 67.0 0.0 2.1e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 ORY78092.1 - 2.4e-08 34.2 0.0 4.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain RRM_1 PF00076.22 ORY78093.1 - 4.2e-43 145.0 1.6 5.1e-21 74.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 ORY78093.1 - 2.8e-09 38.0 0.6 5.4e-07 30.6 0.6 2.5 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 ORY78093.1 - 5.8e-06 26.1 0.0 0.074 12.9 0.0 2.7 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY78093.1 - 0.00024 21.1 0.5 0.0027 17.7 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif RRM_5 PF13893.6 ORY78093.1 - 0.00043 19.9 0.0 0.01 15.4 0.0 2.7 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 ORY78093.1 - 0.056 13.3 0.0 3.4 7.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) RRM_8 PF11835.8 ORY78093.1 - 0.066 13.4 0.3 1.9 8.7 0.0 2.9 3 0 0 3 3 3 0 RRM-like domain RRM_7 PF16367.5 ORY78093.1 - 0.068 13.3 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY78093.1 - 0.11 12.6 0.1 10 6.2 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif MutL_C PF08676.11 ORY78094.1 - 1.6e-23 83.1 0.2 4.3e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ORY78094.1 - 4.2e-20 71.6 0.0 8.7e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY78094.1 - 1.3e-10 41.3 0.1 3.3e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY78094.1 - 5.7e-06 26.8 0.0 1.2e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ALMT PF11744.8 ORY78094.1 - 5.3 5.8 7.3 0.13 11.1 0.7 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter zf-MYND PF01753.18 ORY78097.1 - 3.6e-09 36.6 14.7 6.8e-09 35.7 14.7 1.5 1 0 0 1 1 1 1 MYND finger Kelch_6 PF13964.6 ORY78097.1 - 0.083 13.2 0.0 21 5.6 0.0 2.7 2 0 0 2 2 2 0 Kelch motif zf-Mss51 PF13824.6 ORY78097.1 - 0.58 10.3 11.0 0.7 10.0 9.5 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3589 PF12141.8 ORY78098.1 - 0.013 14.2 0.0 1.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Beta-mannosyltransferases HEAT_EZ PF13513.6 ORY78099.1 - 5.7e-17 61.8 17.4 1.8e-05 25.1 0.1 8.0 8 1 0 8 8 8 3 HEAT-like repeat HEAT PF02985.22 ORY78099.1 - 1.1e-16 59.5 6.7 0.0001 22.2 0.1 8.1 8 0 0 8 8 7 4 HEAT repeat UME PF08064.13 ORY78099.1 - 9.6e-09 35.1 0.0 0.14 12.1 0.0 6.5 4 1 2 6 6 6 1 UME (NUC010) domain HEAT_2 PF13646.6 ORY78099.1 - 1.2e-07 32.0 15.5 0.2 12.1 0.0 8.0 6 3 3 10 10 9 2 HEAT repeats Vac14_Fab1_bd PF12755.7 ORY78099.1 - 4.5e-07 30.4 0.0 0.19 12.3 0.0 4.6 6 0 0 6 6 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY78099.1 - 2e-05 24.7 0.0 0.17 11.9 0.0 3.6 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 ORY78099.1 - 4.8e-05 23.5 0.8 8.3 6.6 0.1 4.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 ORY78099.1 - 0.00035 19.8 2.6 1.4 8.0 0.1 4.8 4 2 1 5 5 5 1 Interferon-related developmental regulator (IFRD) DRIM PF07539.12 ORY78099.1 - 0.0018 16.7 0.0 0.94 7.7 0.0 3.9 4 0 0 4 4 4 1 Down-regulated in metastasis IBN_N PF03810.19 ORY78099.1 - 0.0019 18.1 0.1 0.0043 17.0 0.1 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 ORY78099.1 - 0.0034 16.0 0.2 0.37 9.3 0.0 3.4 4 1 1 5 5 5 2 Adaptin N terminal region MMS19_C PF12460.8 ORY78099.1 - 0.0039 16.4 1.0 6 5.9 0.0 4.5 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 ORY78099.1 - 0.0052 16.4 1.8 2.2 7.8 0.0 4.6 4 2 1 5 5 5 1 CLASP N terminal RIX1 PF08167.12 ORY78099.1 - 0.025 14.3 1.5 3.8 7.2 0.0 4.5 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis PMT PF02366.18 ORY78100.1 - 2e-81 273.2 11.4 5.5e-81 271.8 11.4 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY78100.1 - 1.8e-64 217.0 15.2 1.8e-64 217.0 15.2 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY78100.1 - 3.8e-37 127.9 0.2 6.9e-37 127.1 0.2 1.4 1 0 0 1 1 1 1 MIR domain DUF1240 PF06836.12 ORY78100.1 - 0.26 11.9 2.0 2.4 8.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1240) C2 PF00168.30 ORY78101.1 - 7.3e-75 247.9 0.0 1.8e-19 69.9 0.0 6.1 6 0 0 6 6 6 5 C2 domain Pro_isomerase PF00160.21 ORY78102.1 - 3.5e-47 160.6 0.1 4.5e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aa_trans PF01490.18 ORY78103.1 - 5.1e-78 262.6 13.2 6.3e-78 262.3 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peroxidase_2 PF01328.17 ORY78104.1 - 1.6e-33 116.8 0.0 2.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 RNA_pol_Rpb1_3 PF04983.18 ORY78105.1 - 0.038 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 HLH PF00010.26 ORY78377.1 - 4e-14 52.3 0.5 8.4e-14 51.3 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ADK PF00406.22 ORY78378.1 - 1e-43 149.0 0.0 1.3e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY78378.1 - 1.4e-19 70.9 0.0 2.1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 ORY78378.1 - 1.7e-15 56.7 0.0 3.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 ORY78378.1 - 4.5e-06 27.2 0.0 8.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY78378.1 - 0.03 14.5 0.1 0.18 11.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain Fibrillarin PF01269.17 ORY78379.1 - 2e-105 351.0 0.0 2.4e-105 350.7 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORY78379.1 - 2e-05 24.4 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 ORY78379.1 - 0.0023 17.6 0.0 0.0084 15.8 0.0 1.8 1 1 1 2 2 2 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 ORY78379.1 - 0.0068 16.2 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 ORY78379.1 - 0.019 15.1 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase F-box-like PF12937.7 ORY78380.1 - 0.029 14.3 1.9 0.037 13.9 0.1 2.2 2 0 0 2 2 2 0 F-box-like RRM_1 PF00076.22 ORY78381.1 - 8.7e-13 47.9 0.0 1.2e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY78381.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif LsmAD PF06741.13 ORY78382.1 - 3.8e-22 78.6 0.3 8.3e-22 77.5 0.3 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 ORY78382.1 - 6.9e-14 51.8 0.0 1.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 ORY78382.1 - 0.0073 15.9 7.5 0.9 9.4 0.7 3.3 2 0 0 2 2 2 2 Ataxin-2 C-terminal region TRAM_LAG1_CLN8 PF03798.16 ORY78383.1 - 4e-45 154.0 20.9 4e-45 154.0 20.9 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 ORY78383.1 - 1.1e-16 60.3 0.2 1.1e-16 60.3 0.2 2.5 3 0 0 3 3 3 1 TRAM1-like protein Herpes_pp85 PF04637.12 ORY78383.1 - 0.033 12.6 0.2 0.051 12.0 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) KIND PF16474.5 ORY78383.1 - 2 8.3 3.7 3.4 7.5 3.7 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Beta-lactamase PF00144.24 ORY78384.1 - 8.7e-43 146.8 1.4 2.7e-42 145.2 1.4 1.6 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 ORY78385.1 - 2.1e-42 145.5 0.2 4.6e-42 144.4 0.2 1.4 1 1 0 1 1 1 1 Beta-lactamase 6PGD PF00393.19 ORY78386.1 - 1.8e-127 424.7 0.0 2.2e-127 424.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORY78386.1 - 6.6e-51 172.6 0.0 9.5e-51 172.1 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY78386.1 - 0.006 17.1 0.1 0.012 16.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ORY78386.1 - 0.012 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Beta-lactamase PF00144.24 ORY78387.1 - 3.9e-37 128.2 1.2 2.8e-20 72.9 0.6 2.5 2 1 0 2 2 2 2 Beta-lactamase SPP PF06550.11 ORY78387.1 - 0.098 12.1 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease OPT PF03169.15 ORY78388.1 - 3.9e-131 438.7 45.2 4.5e-131 438.5 45.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1440 PF07274.12 ORY78388.1 - 0.026 14.8 0.9 18 5.7 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1440) F-box-like PF12937.7 ORY78389.1 - 0.023 14.6 0.1 0.023 14.6 0.1 3.0 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.7 ORY78390.1 - 0.0012 18.7 0.3 0.0057 16.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like USP7_ICP0_bdg PF12436.8 ORY78391.1 - 2.4e-85 285.7 0.2 4.5e-85 284.8 0.2 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 ORY78391.1 - 1.1e-63 214.7 0.6 3.2e-62 209.9 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 ORY78391.1 - 2.2e-49 168.3 0.1 3.9e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY78391.1 - 1e-20 74.6 0.0 5.5e-20 72.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HSDR_N_2 PF13588.6 ORY78391.1 - 0.031 14.3 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) PROCN PF08083.11 ORY78393.1 - 7.6e-233 772.5 8.4 1.3e-232 771.7 8.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 ORY78393.1 - 5.8e-124 412.2 0.6 1.3e-123 411.1 0.6 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 ORY78393.1 - 6.9e-88 292.6 4.4 8.5e-88 292.3 2.5 2.2 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 ORY78393.1 - 1.7e-83 278.1 1.3 1.7e-83 278.1 1.3 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 ORY78393.1 - 1.3e-58 196.9 0.0 2.8e-58 195.8 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 ORY78393.1 - 3.6e-48 161.8 0.4 8.2e-48 160.7 0.4 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 ORY78393.1 - 1.4e-35 121.9 0.0 3.1e-35 120.8 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 ORY78393.1 - 0.039 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease 3HCDH_N PF02737.18 ORY78394.1 - 2.1e-53 180.9 0.2 3.1e-53 180.3 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY78394.1 - 7.2e-35 119.5 0.0 2e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY78394.1 - 0.025 14.9 0.3 0.044 14.0 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ORY78394.1 - 0.13 12.5 1.5 0.18 12.0 0.6 1.7 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_RFF PF18321.1 ORY78394.1 - 0.42 11.1 2.5 0.56 10.7 0.1 2.3 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Glyco_transf_92 PF01697.27 ORY78395.1 - 3.3e-09 36.8 0.0 1.9e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 ORY78395.1 - 1.6e-05 25.3 0.0 9.1e-05 22.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 PI3_PI4_kinase PF00454.27 ORY78396.1 - 2e-30 106.4 0.0 4.3e-28 98.8 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY78396.1 - 6.5e-18 64.8 0.0 1.3e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Acyl-CoA_dh_1 PF00441.24 ORY78396.1 - 0.047 13.9 0.4 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain AvrRpt-cleavage PF05627.11 ORY78396.1 - 0.28 10.6 1.1 0.73 9.2 1.1 1.7 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr PUB PF09409.10 ORY78397.1 - 1e-09 38.2 0.0 4.4e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 PUB domain GCV_H PF01597.19 ORY78399.1 - 3.4e-42 143.2 0.0 4e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 ORY78399.1 - 3.9e-05 23.4 0.1 7.7e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 ORY78399.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HA2 PF04408.23 ORY78401.1 - 1.4e-14 54.2 1.0 3.7e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY78401.1 - 4.2e-13 49.6 0.0 1.1e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dsrm PF00035.26 ORY78401.1 - 7.9e-13 48.9 0.0 6.6e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 ORY78401.1 - 2.1e-08 34.4 0.0 1.5e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ORY78401.1 - 2.3e-06 27.5 0.0 4.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 ORY78401.1 - 0.0063 16.6 0.0 0.14 12.4 0.0 2.8 3 0 0 3 3 3 1 Dicer dimerisation domain AAA_19 PF13245.6 ORY78401.1 - 0.0066 16.8 0.0 0.025 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain OmpH PF03938.14 ORY78401.1 - 0.42 11.0 1.9 0.75 10.1 1.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LRR_4 PF12799.7 ORY78405.1 - 0.25 11.8 8.2 3.4 8.2 0.2 4.3 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) Pox_MCEL PF03291.16 ORY78407.1 - 4.9e-83 279.0 0.0 7.6e-83 278.4 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 ORY78407.1 - 8e-16 58.5 0.0 1.5e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY78407.1 - 6.3e-13 48.8 0.0 9.6e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY78407.1 - 4.9e-12 46.5 0.0 7.8e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY78407.1 - 2.2e-10 41.0 0.0 4.2e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY78407.1 - 1.7e-08 34.5 0.0 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORY78407.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.14 ORY78407.1 - 0.028 14.0 0.0 0.059 12.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Swi3 PF07962.12 ORY78408.1 - 1.4e-30 105.1 1.1 2e-30 104.6 1.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Epimerase PF01370.21 ORY78409.1 - 0.00029 20.4 0.0 0.00063 19.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY78409.1 - 0.00029 20.8 0.0 0.00068 19.6 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY78409.1 - 0.017 14.2 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4235 PF14019.6 ORY78409.1 - 0.043 13.9 0.5 0.043 13.9 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) TMEM51 PF15345.6 ORY78410.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 MSC PF09402.10 ORY78411.1 - 7.7e-78 262.3 0.0 1.3e-77 261.5 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ORY78411.1 - 1.7e-08 34.0 0.1 1.7e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 HeH/LEM domain Mem_trans PF03547.18 ORY78411.1 - 0.0089 14.5 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 1 Membrane transport protein LAP1C PF05609.12 ORY78411.1 - 5.2 6.1 12.4 7.8 5.5 12.4 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2315 PF10231.9 ORY78412.1 - 1e-18 67.6 0.8 9.8e-18 64.4 0.8 2.0 1 1 0 1 1 1 1 Apoptogenic protein 1 Adhesin_E PF16747.5 ORY78412.1 - 0.082 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Surface-adhesin protein E DUF5546 PF17700.1 ORY78412.1 - 0.61 10.4 6.0 0.21 11.9 3.4 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5546) LRR_4 PF12799.7 ORY78414.1 - 1.4 9.4 9.9 5.6 7.5 0.7 4.3 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY78415.1 - 0.0028 17.5 0.2 0.0071 16.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY78415.1 - 0.044 14.2 2.6 34 5.0 0.1 4.5 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY78415.1 - 3.8 7.8 4.9 69 3.9 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat BTB_2 PF02214.22 ORY78416.1 - 0.015 15.6 0.1 0.051 13.9 0.1 1.8 1 1 0 1 1 1 0 BTB/POZ domain DUF3886 PF13025.6 ORY78416.1 - 0.21 11.8 3.1 0.34 11.1 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) NAD_kinase PF01513.21 ORY78417.1 - 1.9e-57 194.7 0.0 2.5e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ORY78417.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SAE2 PF08573.10 ORY78418.1 - 5.1e-16 59.8 7.3 5.1e-16 59.8 7.3 2.1 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-C4 PF00105.18 ORY78418.1 - 0.011 16.2 5.1 0.059 13.8 5.1 2.2 1 1 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF4551 PF15087.6 ORY78418.1 - 0.61 8.9 8.3 0.71 8.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ras PF00071.22 ORY78420.1 - 6.7e-49 165.6 0.0 8.2e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY78420.1 - 8e-20 71.3 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY78420.1 - 6.1e-06 25.8 0.0 1.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY78420.1 - 0.092 12.7 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 ORY78420.1 - 0.19 12.1 0.0 1.5 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PIG-X PF08320.12 ORY78421.1 - 9.8e-34 117.1 0.0 1.2e-33 116.8 0.0 1.0 1 0 0 1 1 1 1 PIG-X / PBN1 AidB_N PF18158.1 ORY78421.1 - 0.22 11.4 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Adaptive response protein AidB N-terminal domain FATC PF02260.20 ORY78421.1 - 0.53 10.2 3.2 0.29 11.0 0.9 1.7 2 0 0 2 2 2 0 FATC domain Lipase_GDSL_2 PF13472.6 ORY78422.1 - 2.7e-27 96.3 0.1 3.5e-27 95.9 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY78422.1 - 1.7e-16 60.8 0.0 3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Beta-lactamase PF00144.24 ORY78423.1 - 1.7e-19 70.3 0.0 4.5e-19 68.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase GDPD PF03009.17 ORY78424.1 - 2.7e-26 92.8 0.0 1.1e-25 90.8 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 ORY78424.1 - 7.9e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Hydrolase_4 PF12146.8 ORY78426.1 - 2.5e-17 62.9 0.4 9.2e-15 54.6 0.4 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY78426.1 - 5.9e-13 49.0 0.7 4.7e-10 39.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY78426.1 - 9.6e-07 29.6 0.1 2e-06 28.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORY78426.1 - 6.3e-05 22.4 0.0 0.33 10.2 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.21 ORY78426.1 - 0.00021 20.8 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 ORY78426.1 - 0.00043 19.5 0.0 0.00074 18.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Peptidase_S15 PF02129.18 ORY78426.1 - 0.00095 18.8 0.2 1.2 8.6 0.1 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 ORY78426.1 - 0.0054 16.6 0.2 0.015 15.1 0.0 1.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORY78426.1 - 0.028 14.1 0.0 0.088 12.5 0.0 1.7 1 1 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 ORY78426.1 - 0.2 11.2 0.0 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Asn_synthase PF00733.21 ORY78427.1 - 8.3e-93 311.9 0.2 6.5e-57 193.8 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORY78427.1 - 8.9e-36 122.5 0.0 1.5e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY78427.1 - 3.5e-29 101.7 0.0 8.9e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORY78427.1 - 4.6e-05 23.0 0.0 8.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ORY78427.1 - 0.017 14.3 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 ORY78427.1 - 0.048 13.1 0.1 0.092 12.2 0.1 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC TPR_1 PF00515.28 ORY78428.1 - 2e-28 97.0 3.2 8.6e-09 34.9 0.1 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY78428.1 - 2.9e-27 92.5 10.4 7e-08 32.0 0.1 8.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY78428.1 - 6.7e-21 72.7 1.6 0.00018 21.4 0.0 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY78428.1 - 2.4e-19 69.7 5.0 2e-06 28.3 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY78428.1 - 6.8e-18 64.1 0.6 2.3e-05 24.0 0.0 5.7 4 1 1 5 5 5 5 TPR repeat TPR_14 PF13428.6 ORY78428.1 - 3.1e-16 58.7 15.1 0.0047 17.6 0.0 8.1 5 1 4 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY78428.1 - 2.3e-15 56.9 5.6 0.00053 20.4 0.1 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY78428.1 - 8.3e-15 54.0 0.2 0.12 12.8 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY78428.1 - 5.5e-13 48.9 8.4 1.9e-05 24.8 0.0 5.4 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY78428.1 - 2.9e-12 45.7 3.9 0.28 11.3 0.0 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY78428.1 - 6.8e-10 39.1 15.4 4.8e-05 23.6 0.5 6.7 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY78428.1 - 2e-06 27.8 9.5 0.022 14.9 0.1 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY78428.1 - 2.1e-06 28.0 4.8 0.55 11.0 0.0 7.0 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY78428.1 - 8.7e-06 25.1 1.7 0.089 12.0 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY78428.1 - 0.0028 17.5 11.1 0.82 9.6 0.1 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY78428.1 - 0.0029 17.0 0.0 0.032 13.6 0.0 2.5 2 1 0 2 2 2 1 MalT-like TPR region TPR_20 PF14561.6 ORY78428.1 - 0.055 13.8 0.0 5.9 7.3 0.0 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 ORY78428.1 - 0.14 12.9 3.3 56 4.6 0.1 3.8 3 0 0 3 3 3 0 Sel1 repeat TPR_4 PF07721.14 ORY78428.1 - 0.38 11.5 3.7 16 6.5 0.5 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat BTAD PF03704.17 ORY78428.1 - 2.5 8.5 5.5 25 5.3 0.2 3.4 3 1 1 4 4 3 0 Bacterial transcriptional activator domain UQ_con PF00179.26 ORY78430.1 - 2.7e-17 62.7 0.0 3.1e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY78430.1 - 0.014 15.7 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF3760 PF12586.8 ORY78432.1 - 0.016 15.4 1.2 0.03 14.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) LRR_4 PF12799.7 ORY78432.1 - 0.029 14.8 10.9 19 5.9 0.0 5.3 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) AAA_3 PF07726.11 ORY78432.1 - 0.089 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ECH_1 PF00378.20 ORY78433.1 - 1.7e-40 138.9 0.0 2.2e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY78433.1 - 7.4e-27 94.7 0.0 8.2e-24 84.7 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Transposase_21 PF02992.14 ORY78433.1 - 0.059 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 EF_assoc_2 PF08356.12 ORY78435.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 EF hand associated CDP-OH_P_transf PF01066.21 ORY78436.1 - 3.5e-12 46.9 0.4 3.5e-12 46.9 0.4 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WD40 PF00400.32 ORY78437.1 - 3.4e-41 138.4 21.6 3.3e-09 37.2 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY78437.1 - 7.7e-20 71.0 2.0 0.0017 18.6 0.0 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY78437.1 - 7.2e-12 45.6 0.9 1.7e-06 28.0 0.2 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY78437.1 - 2e-07 30.3 0.1 0.0055 15.7 0.0 3.8 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 ORY78437.1 - 0.0018 17.4 0.0 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 ORY78437.1 - 0.047 13.0 0.0 0.52 9.6 0.0 2.2 1 1 2 3 3 3 0 WD40-like domain Cyt-b5 PF00173.28 ORY78440.1 - 4.2e-21 74.9 0.0 5.4e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Elongin_A PF06881.11 ORY78441.1 - 1.3e-20 73.8 0.0 1.9e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RCC1 PF00415.18 ORY78442.1 - 2.8e-23 82.3 2.6 4.3e-08 33.7 0.0 7.8 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY78442.1 - 2.2e-11 43.3 10.7 5.3e-07 29.3 0.1 6.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Sushi PF00084.20 ORY78443.1 - 0.58 10.8 5.5 9.9 6.9 0.7 2.6 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) SLR1-BP PF07333.12 ORY78443.1 - 2.6 8.6 15.2 4.4 7.8 5.0 2.6 2 0 0 2 2 2 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) Dynactin_p22 PF07426.11 ORY78444.1 - 8.2e-16 58.3 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 Lebercilin PF15619.6 ORY78444.1 - 0.048 13.3 0.0 0.097 12.3 0.0 1.5 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Ribosomal_L3 PF00297.22 ORY78446.1 - 1.3e-16 60.6 2.4 6.7e-15 54.9 2.4 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 LRR_6 PF13516.6 ORY78447.1 - 3.4e-13 48.5 4.6 0.7 10.1 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 ORY78447.1 - 0.00031 20.9 2.6 36 5.4 2.4 6.3 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY78447.1 - 0.00065 19.4 13.6 2.1 8.2 0.1 6.3 5 2 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 ORY78447.1 - 0.0008 19.7 19.3 1.7 9.2 1.3 6.7 4 2 4 8 8 8 2 Leucine Rich repeats (2 copies) Radial_spoke PF04712.12 ORY78447.1 - 0.34 9.8 12.3 8.8 5.1 0.0 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein Myc_N PF01056.18 ORY78447.1 - 0.64 9.9 6.5 0.91 9.4 6.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region PTPRCAP PF15713.5 ORY78447.1 - 1.2 9.4 14.2 2.2 8.6 14.2 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Drc1-Sld2 PF11719.8 ORY78447.1 - 1.5 8.2 5.4 2.7 7.4 5.4 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein PRP38_assoc PF12871.7 ORY78447.1 - 3.7 8.2 12.7 7.5 7.2 12.7 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Paf1 PF03985.13 ORY78447.1 - 4.1 6.3 13.2 5.9 5.8 13.2 1.1 1 0 0 1 1 1 0 Paf1 Astro_capsid_p PF12226.8 ORY78447.1 - 6.4 5.8 9.9 10 5.2 9.9 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 ORY78447.1 - 8 4.5 12.9 11 4.1 12.9 1.1 1 0 0 1 1 1 0 Nop14-like family S-antigen PF05756.11 ORY78447.1 - 8.4 6.8 8.7 15 6.0 8.7 1.3 1 0 0 1 1 1 0 S-antigen protein Ribosomal_60s PF00428.19 ORY78448.1 - 1.8e-27 95.7 13.6 2.2e-27 95.5 13.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 ORY78448.1 - 0.2 10.1 1.4 0.27 9.7 1.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein B56 PF01603.20 ORY78449.1 - 2.6e-192 639.3 0.3 3.1e-192 639.1 0.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec66 PF09802.9 ORY78450.1 - 1.2e-37 129.2 4.4 9.8e-21 74.1 0.0 2.1 1 1 1 2 2 2 2 Preprotein translocase subunit Sec66 F-box-like PF12937.7 ORY78452.1 - 0.046 13.6 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 F-box-like BLACT_WH PF17778.1 ORY78453.1 - 8.6e-13 48.0 0.0 2.9e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 ORY78453.1 - 6.3e-08 32.9 1.8 1.9e-07 31.3 1.1 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY78453.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain ELMO_CED12 PF04727.13 ORY78454.1 - 3.8e-27 95.5 0.0 5e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF2427 PF10348.9 ORY78455.1 - 0.0052 16.5 0.3 0.0052 16.5 0.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) NMT_C PF02799.15 ORY78456.1 - 1.8e-75 253.1 0.0 3.6e-75 252.1 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 ORY78456.1 - 1.9e-72 242.3 0.0 2.9e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 ORY78456.1 - 0.00019 21.7 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY78456.1 - 0.0054 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain INO80_Ies4 PF08193.11 ORY78456.1 - 0.74 9.8 9.7 1.2 9.1 9.7 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 GCP_N_terminal PF17681.1 ORY78457.1 - 1e-21 77.9 0.0 1.4e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY78457.1 - 2.9e-16 59.8 0.0 6.6e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal FAM176 PF14851.6 ORY78457.1 - 2.3 7.9 4.6 1.1 8.9 1.2 2.1 2 0 0 2 2 2 0 FAM176 family Chorismate_bind PF00425.18 ORY78458.1 - 3.6e-87 292.2 0.0 1.3e-86 290.4 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 ORY78458.1 - 1.8e-25 89.8 0.0 5e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region PCuAC PF04314.13 ORY78458.1 - 0.048 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Copper chaperone PCu(A)C F-box-like PF12937.7 ORY78459.1 - 0.03 14.2 0.1 0.07 13.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like STAG PF08514.11 ORY78462.1 - 7.8e-32 109.5 2.1 7.8e-32 109.5 2.1 2.5 2 0 0 2 2 2 1 STAG domain TIMELESS_C PF05029.13 ORY78462.1 - 0.0004 19.7 8.2 0.0004 19.7 8.2 5.0 4 2 1 5 5 5 2 Timeless protein C terminal region Drc1-Sld2 PF11719.8 ORY78462.1 - 0.0034 17.0 5.8 0.0034 17.0 5.8 5.4 5 1 1 6 6 6 1 DNA replication and checkpoint protein CBM_21 PF03370.13 ORY78463.1 - 1.4e-26 92.9 0.1 2.4e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY78463.1 - 4.1e-09 36.9 0.1 8.7e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) NAD_binding_10 PF13460.6 ORY78464.1 - 4.5e-08 33.2 0.0 6.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY78464.1 - 0.029 13.8 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY78464.1 - 0.058 12.9 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 ORY78464.1 - 0.062 12.4 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_C14 PF00656.22 ORY78464.1 - 0.074 13.0 0.0 0.095 12.6 0.0 1.1 1 0 0 1 1 1 0 Caspase domain Acyl-CoA_dh_1 PF00441.24 ORY78465.1 - 8.9e-34 116.9 1.9 8.9e-34 116.9 1.9 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY78465.1 - 1.9e-23 82.4 0.2 3.2e-23 81.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY78465.1 - 1e-13 51.9 1.9 7.6e-13 49.1 1.9 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY78465.1 - 3.3e-05 24.2 0.6 3.3e-05 24.2 0.6 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain FAM180 PF15173.6 ORY78465.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 FAM180 family HhH-GPD PF00730.25 ORY78466.1 - 9.1e-17 61.5 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY78466.1 - 0.00019 21.1 1.4 0.051 13.5 0.0 2.9 3 0 0 3 3 3 2 Helix-hairpin-helix motif VSP PF03302.13 ORY78467.1 - 0.0039 16.1 29.4 0.0039 16.1 29.4 6.7 1 1 5 6 6 6 3 Giardia variant-specific surface protein DUF4381 PF14316.6 ORY78467.1 - 0.0079 16.4 0.3 0.015 15.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) DUF2207 PF09972.9 ORY78467.1 - 0.058 12.2 0.1 0.084 11.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4083 PF13314.6 ORY78467.1 - 0.18 11.7 0.2 0.37 10.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Stevor PF17410.2 ORY78467.1 - 6.7 6.2 10.2 0.05 13.2 1.0 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame OPA3 PF07047.12 ORY78468.1 - 5.8e-43 145.6 0.2 1e-42 144.9 0.2 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) MFS_1 PF07690.16 ORY78469.1 - 3.8e-40 137.9 20.5 3.8e-40 137.9 20.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1772 PF08592.11 ORY78469.1 - 0.025 14.9 18.1 0.33 11.3 0.9 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) COX2-transmemb PF09125.10 ORY78469.1 - 0.11 12.3 0.1 0.11 12.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane Hydantoinase_B PF02538.14 ORY78470.1 - 2.7e-207 689.3 0.4 3.1e-207 689.1 0.4 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORY78471.1 - 8.7e-96 320.6 0.1 1.4e-95 319.9 0.1 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY78471.1 - 8.9e-54 181.9 0.3 4.7e-52 176.3 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Mu-like_Com PF10122.9 ORY78471.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Mu-like prophage protein Com SH3_9 PF14604.6 ORY78474.1 - 3.9e-09 36.2 0.1 7.8e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY78474.1 - 0.00035 20.1 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY78474.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain CUE PF02845.16 ORY78475.1 - 1.8e-09 37.1 0.2 3e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 CUE domain MRI PF15325.6 ORY78475.1 - 0.013 16.6 2.7 0.013 16.6 2.7 3.9 2 1 2 5 5 5 0 Modulator of retrovirus infection Phe_tRNA-synt_N PF02912.18 ORY78475.1 - 0.078 12.9 0.6 0.16 11.9 0.6 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain DMA PF03474.14 ORY78475.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 DMRTA motif Fungal_trans PF04082.18 ORY78476.1 - 6.3e-20 71.3 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY78476.1 - 1.2e-06 28.5 6.5 2.4e-06 27.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 ORY78477.1 - 2.5e-42 144.4 0.0 4e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY78477.1 - 4.4e-13 48.8 0.6 8.1e-13 48.0 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORY78477.1 - 1.3e-10 41.0 0.1 3.3e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 ORY78477.1 - 7.7e-07 29.7 0.0 0.00016 22.1 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 ORY78477.1 - 1.7e-06 28.1 0.0 2.5e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY78477.1 - 2.2e-06 27.9 0.0 4.2e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY78477.1 - 3.7e-05 23.5 0.0 7.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY78477.1 - 9.6e-05 22.7 0.0 0.0048 17.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY78477.1 - 0.001 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 ORY78477.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ORY78477.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORY78477.1 - 0.0036 16.8 0.0 0.0076 15.8 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORY78477.1 - 0.0053 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ORY78477.1 - 0.0076 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY78477.1 - 0.0079 16.7 0.1 0.026 15.1 0.0 2.0 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 ORY78477.1 - 0.0084 16.5 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 ORY78477.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY78477.1 - 0.014 15.1 0.0 0.037 13.7 0.0 1.7 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORY78477.1 - 0.019 14.7 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY78477.1 - 0.021 14.3 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 ORY78477.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 ORY78477.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 ORY78477.1 - 0.03 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY78477.1 - 0.036 13.6 0.2 0.076 12.6 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY78477.1 - 0.044 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY78477.1 - 0.069 12.5 0.2 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 ORY78477.1 - 0.07 13.0 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 ORY78477.1 - 0.072 12.8 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.6 ORY78477.1 - 0.081 12.7 0.2 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY78477.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 ORY78477.1 - 0.18 12.1 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 ORY78478.1 - 2.4e-44 150.4 0.1 2.7e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY78478.1 - 0.0064 16.8 0.0 0.0079 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 ORY78478.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 ORY78478.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Prok-E2_A PF14457.6 ORY78478.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A Exo_endo_phos PF03372.23 ORY78479.1 - 1.4e-08 34.5 0.0 1.9e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vac_ImportDeg PF09783.9 ORY78480.1 - 1.8e-43 148.1 0.0 2.5e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Calici_MSP PF05752.11 ORY78480.1 - 0.13 12.1 0.1 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Calicivirus minor structural protein SRPRB PF09439.10 ORY78481.1 - 6.6e-14 51.7 0.0 9.2e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORY78481.1 - 1.2e-05 25.0 0.0 2e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY78481.1 - 0.0034 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY78481.1 - 0.086 13.2 1.2 0.16 12.3 0.3 1.8 1 1 1 2 2 2 0 AAA ATPase domain IMS PF00817.20 ORY78482.1 - 3.5e-36 124.4 0.1 1.7e-35 122.2 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 ORY78482.1 - 1.1e-21 77.0 4.8 2.6e-21 75.8 4.8 1.7 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_C PF11799.8 ORY78482.1 - 5.5e-12 46.4 0.0 1.4e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 ORY78482.1 - 1.9e-07 31.4 0.0 4.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 ORY78482.1 - 1.3e-05 25.2 0.1 0.00019 21.6 0.0 2.9 3 0 0 3 3 3 1 IMS family HHH motif LIG3_BRCT PF16759.5 ORY78482.1 - 0.00047 20.4 0.0 0.00096 19.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 ORY78482.1 - 0.0022 18.3 0.0 0.0051 17.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain SPX PF03105.19 ORY78483.1 - 1.4e-25 91.0 0.2 8.2e-10 39.1 0.0 3.6 2 1 1 4 4 4 3 SPX domain L71 PF02448.15 ORY78483.1 - 2.3 8.7 4.5 8.4 6.9 0.8 2.3 2 0 0 2 2 2 0 L71 family Fungal_trans PF04082.18 ORY78485.1 - 4.5e-17 61.9 0.7 6.4e-17 61.5 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY78485.1 - 7.6e-07 29.2 10.3 1.5e-06 28.2 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.29 ORY78486.1 - 1.9e-42 145.5 0.0 3.2e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY78486.1 - 2.6e-23 82.1 10.5 3.2e-18 65.8 1.3 2.7 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 ORY78486.1 - 4.2e-23 80.9 1.4 6.2e-22 77.1 0.5 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 ORY78486.1 - 3.9e-20 71.4 2.1 3.3e-09 36.5 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 ORY78486.1 - 1.1e-15 58.1 0.6 2.4e-14 53.7 0.6 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1445 PF07286.12 ORY78487.1 - 9e-58 194.3 0.0 1.2e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) F-box-like PF12937.7 ORY78488.1 - 2.4e-05 24.2 0.7 6.2e-05 22.8 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY78488.1 - 0.079 12.9 1.6 0.67 9.9 0.7 2.9 2 1 0 2 2 2 0 F-box domain Macro PF01661.21 ORY78489.1 - 8.7e-37 125.8 0.0 1.3e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Macro domain Ribosomal_L7Ae PF01248.26 ORY78490.1 - 5.8e-26 90.1 0.1 7e-26 89.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 ORY78490.1 - 0.00045 20.1 0.0 0.00059 19.7 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 ORY78490.1 - 0.0011 19.1 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 AA_permease PF00324.21 ORY78824.1 - 1.1e-130 436.5 41.0 1.4e-130 436.2 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY78824.1 - 2e-31 109.3 40.0 2e-31 109.3 40.0 1.6 1 1 1 2 2 2 1 Amino acid permease WTF PF03303.13 ORY78824.1 - 1.6 8.4 8.2 3.5 7.3 8.2 1.5 1 0 0 1 1 1 0 WTF protein 2-oxoacid_dh PF00198.23 ORY78825.1 - 7.6e-78 261.2 0.0 1e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY78825.1 - 9e-17 60.7 1.9 9e-17 60.7 1.9 2.9 3 1 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY78825.1 - 3.5e-15 56.0 0.1 1.1e-14 54.5 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain RNA_pol_Rpc4 PF05132.14 ORY78825.1 - 0.64 10.4 4.5 0.16 12.4 0.4 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Stm1_N PF09598.10 ORY78825.1 - 1.2 10.1 13.6 0.046 14.6 6.4 2.3 2 0 0 2 2 2 0 Stm1 Pkinase PF00069.25 ORY78826.1 - 3.1e-27 95.6 0.0 3.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY78826.1 - 2.7e-15 56.4 0.0 3.2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY78826.1 - 6.5e-09 35.0 0.0 9.3e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY78826.1 - 0.0012 18.8 0.1 0.0053 16.7 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY78826.1 - 0.0088 15.1 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase MFS_1 PF07690.16 ORY78829.1 - 9.1e-30 103.8 44.0 1.2e-27 96.8 21.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY78829.1 - 5.4e-05 22.7 0.7 5.4e-05 22.7 0.7 2.8 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Lung_7-TM_R PF06814.13 ORY78830.1 - 4.5e-61 206.7 15.2 5.6e-61 206.4 15.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PAXNEB PF05625.11 ORY78831.1 - 2.9e-65 220.8 0.0 5.8e-65 219.8 0.0 1.4 1 1 0 1 1 1 1 PAXNEB protein Calpain_inhib PF00748.19 ORY78831.1 - 2.7 8.5 13.5 0.37 11.3 9.0 1.8 2 0 0 2 2 2 0 Calpain inhibitor Peptidase_S9_N PF02897.15 ORY78833.1 - 2.1e-92 310.1 2.0 2.9e-92 309.6 2.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY78833.1 - 6.2e-58 195.7 0.0 1e-57 195.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY78833.1 - 0.015 15.0 0.1 5.5 6.5 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2794 PF10984.8 ORY78833.1 - 0.042 14.0 0.1 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2794) Peptidase_S28 PF05577.12 ORY78833.1 - 0.085 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ribosomal_L37 PF08561.10 ORY78833.1 - 0.098 13.2 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 PD40 PF07676.12 ORY78833.1 - 8.3 6.5 16.6 0.18 11.8 2.5 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Med10 PF09748.9 ORY78834.1 - 2.5e-32 111.4 0.0 2.9e-32 111.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3546 PF12066.8 ORY78835.1 - 7.1e-11 42.3 0.2 1.8e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 ORY78835.1 - 7e-10 39.6 0.0 7e-10 39.6 0.0 2.9 3 1 0 3 3 3 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 ORY78835.1 - 8.7e-06 25.4 4.0 1.7e-05 24.5 2.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 ORY78835.1 - 0.0024 17.6 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF629 PF04780.12 ORY78835.1 - 0.11 11.0 0.6 0.22 10.0 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 ORY78835.1 - 0.32 11.5 5.7 0.27 11.8 0.9 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY78835.1 - 0.6 11.1 5.8 0.8 10.7 1.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY78835.1 - 0.76 10.2 4.5 1 9.7 0.7 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ORY78835.1 - 1.1 9.3 11.3 0.089 12.8 2.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Actin PF00022.19 ORY78836.1 - 1.1e-150 501.8 0.0 5e-150 499.7 0.0 1.7 1 1 0 1 1 1 1 Actin Methyltransf_29 PF03141.16 ORY78836.1 - 0.055 12.0 0.0 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3328 PF11807.8 ORY78837.1 - 0.13 12.0 1.3 0.17 11.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) FAP PF07174.11 ORY78837.1 - 4.2 6.8 16.9 0.77 9.2 13.0 1.7 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) F-box PF00646.33 ORY78838.1 - 0.0052 16.6 0.6 0.056 13.3 0.1 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY78838.1 - 0.062 13.2 1.4 0.11 12.4 0.3 2.1 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 ORY78840.1 - 5.2e-05 23.5 1.4 1.4 9.5 0.1 5.5 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY78840.1 - 0.00018 21.3 2.4 3 8.1 0.0 6.1 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.6 ORY78840.1 - 0.00095 18.9 3.9 0.038 13.8 0.0 4.6 5 2 0 5 5 5 1 Leucine rich repeat Raptor_N PF14538.6 ORY78841.1 - 1.2e-60 203.7 0.0 2.3e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 ORY78841.1 - 3e-09 37.3 4.2 0.48 11.4 0.0 6.8 8 0 0 8 8 8 3 WD domain, G-beta repeat HEAT PF02985.22 ORY78841.1 - 7e-05 22.8 0.3 0.13 12.6 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat ANAPC4_WD40 PF12894.7 ORY78841.1 - 0.0019 18.5 0.0 2.4 8.5 0.0 4.5 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain APG12 PF04110.13 ORY78842.1 - 3.4e-33 113.9 0.1 4.2e-33 113.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 ORY78842.1 - 0.00045 20.4 0.0 0.00053 20.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Beta_helix PF13229.6 ORY78843.1 - 2e-06 27.7 14.8 5.9e-06 26.2 14.1 2.2 1 1 0 1 1 1 1 Right handed beta helix region Mucin PF01456.17 ORY78843.1 - 0.00051 20.0 34.3 0.00051 20.0 34.3 2.7 3 0 0 3 3 3 1 Mucin-like glycoprotein NosD PF05048.13 ORY78843.1 - 0.0035 16.6 2.5 0.0035 16.6 2.5 2.3 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) AJAP1_PANP_C PF15298.6 ORY78843.1 - 4.1 7.6 18.8 8.8 6.5 18.8 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus TPR_2 PF07719.17 ORY78844.1 - 5.4e-06 26.1 0.9 0.0026 17.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY78844.1 - 3e-05 23.6 2.4 0.0041 16.9 0.3 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY78844.1 - 0.00041 20.4 2.6 0.065 13.4 0.5 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY78844.1 - 0.0022 18.5 0.3 0.011 16.2 0.3 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY78844.1 - 0.0026 18.4 6.8 0.092 13.6 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY78844.1 - 0.0036 16.9 0.5 1.9 8.3 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 ORY78844.1 - 0.021 15.1 1.9 0.42 10.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY78844.1 - 0.13 12.9 0.6 8.5 7.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY78844.1 - 0.45 11.2 4.1 18 6.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Gln-synt_C PF00120.24 ORY78845.1 - 0.024 13.7 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain SLS PF14611.6 ORY78845.1 - 0.2 11.5 0.1 0.27 11.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Gln-synt_C PF00120.24 ORY78846.1 - 1.7e-15 56.9 0.0 8.7e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 ORY78846.1 - 3.2e-12 46.0 0.0 5.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Ribosomal_L41 PF05162.13 ORY78847.1 - 3.7e-08 33.3 25.1 3.7e-08 33.3 25.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L41 LPG_synthase_TM PF03706.13 ORY78847.1 - 8 5.9 13.1 0.58 9.6 6.2 2.0 1 1 1 2 2 2 0 Lysylphosphatidylglycerol synthase TM region Ccdc124 PF06244.12 ORY78848.1 - 0.0062 17.1 0.7 0.0068 16.9 0.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 60KD_IMP PF02096.20 ORY78848.1 - 0.17 11.8 0.1 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein LIDHydrolase PF10230.9 ORY78849.1 - 9.4e-51 172.9 0.0 1.1e-50 172.7 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 ORY78849.1 - 5.9e-06 27.0 1.4 8.7e-06 26.5 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY78849.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 ORY78849.1 - 0.015 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 ORY78849.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LRR_4 PF12799.7 ORY78850.1 - 0.11 13.0 0.5 1.9 9.1 0.2 2.7 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY78853.1 - 0.0092 15.9 1.7 0.1 12.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like UPRTase PF14681.6 ORY78855.1 - 1.8e-80 269.3 0.0 2.1e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY78855.1 - 0.0012 18.4 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 ORY78855.1 - 0.14 12.1 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) RRM_1 PF00076.22 ORY78856.1 - 7.1e-16 57.8 0.0 5.6e-08 32.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BUD22 PF09073.10 ORY78856.1 - 0.00052 19.5 46.4 0.00052 19.5 46.4 2.5 3 0 0 3 3 3 1 BUD22 CDC45 PF02724.14 ORY78856.1 - 1.1 7.4 36.1 0.079 11.3 27.9 2.2 2 0 0 2 2 2 0 CDC45-like protein Presenilin PF01080.17 ORY78856.1 - 2.5 6.8 21.0 0.15 10.8 12.8 2.1 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.13 ORY78856.1 - 3.6 7.5 29.1 0.36 10.8 19.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.9 ORY78856.1 - 7.2 5.0 18.5 0.074 11.6 8.9 1.9 2 0 0 2 2 2 0 Macoilin family Nop14 PF04147.12 ORY78856.1 - 8.9 4.4 48.0 0.056 11.7 39.2 1.6 2 0 0 2 2 2 0 Nop14-like family Abhydro_lipase PF04083.16 ORY78857.1 - 5e-15 54.8 0.0 1.1e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ORY78857.1 - 8.2e-07 28.9 0.1 1.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY78857.1 - 0.00072 18.9 0.0 0.002 17.4 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 ORY78857.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Copper-fist PF00649.18 ORY78858.1 - 1.9e-21 75.3 3.4 1.9e-21 75.3 3.4 2.1 1 1 1 2 2 2 1 Copper fist DNA binding domain AA_permease PF00324.21 ORY78860.1 - 4.6e-136 454.2 32.1 5.5e-136 453.9 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY78860.1 - 3.1e-29 102.1 35.5 4e-29 101.7 35.5 1.2 1 0 0 1 1 1 1 Amino acid permease RES PF08808.11 ORY78860.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 RES domain AA_permease PF00324.21 ORY78861.1 - 6.5e-122 407.5 33.8 8e-122 407.2 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY78861.1 - 2.1e-27 96.0 36.2 3.4e-27 95.4 35.8 1.4 1 1 0 1 1 1 1 Amino acid permease RES PF08808.11 ORY78861.1 - 0.16 11.9 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 RES domain SURF1 PF02104.15 ORY78862.1 - 2.2e-45 155.1 0.0 2.7e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 SURF1 family MRP-L28 PF09812.9 ORY78863.1 - 1.9e-05 24.9 0.2 3.3e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF3666 PF12408.8 ORY78863.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase eIF3_N PF09440.10 ORY78864.1 - 6.9e-50 168.9 3.2 3.5e-49 166.7 1.2 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 ORY78864.1 - 6.8e-12 45.8 0.0 1.9e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 PCI domain ADH_N PF08240.12 ORY78865.1 - 2.5e-25 88.5 3.2 6.2e-25 87.2 3.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY78865.1 - 1.2e-21 77.0 0.4 2.4e-21 76.1 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY78865.1 - 0.09 12.1 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box-like PF12937.7 ORY78866.1 - 0.00019 21.3 0.6 0.00089 19.1 0.5 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORY78866.1 - 0.014 15.3 0.1 0.045 13.6 0.1 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY78867.1 - 1.3e-05 25.0 4.9 1.3e-05 25.0 4.9 3.0 3 1 1 4 4 4 1 F-box-like F-box PF00646.33 ORY78867.1 - 0.016 15.1 3.4 0.04 13.8 0.2 3.4 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 ORY78869.1 - 0.034 14.0 0.3 0.12 12.3 0.3 2.0 1 1 0 1 1 1 0 F-box-like Abp2 PF09441.10 ORY78869.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 ARS binding protein 2 Es2 PF09751.9 ORY78870.1 - 6.1e-101 339.3 3.4 6.1e-101 339.3 3.4 2.2 3 0 0 3 3 3 1 Nuclear protein Es2 Aminotran_1_2 PF00155.21 ORY78870.1 - 4.4e-90 302.5 0.0 6e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 ORY78871.1 - 1.1e-10 41.1 0.0 5e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY78871.1 - 0.039 14.1 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF423 PF04241.15 ORY78872.1 - 3.3e-19 68.9 2.7 5.2e-19 68.2 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) F-box-like PF12937.7 ORY78873.1 - 0.0002 21.2 0.2 0.00047 20.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY78873.1 - 0.0012 18.7 1.8 0.0019 18.0 0.2 2.1 2 0 0 2 2 2 1 F-box domain Beta_helix PF13229.6 ORY78874.1 - 4.2e-12 46.2 2.1 8.8e-09 35.4 1.2 2.8 2 1 1 3 3 3 3 Right handed beta helix region NosD PF05048.13 ORY78874.1 - 0.0002 20.7 1.6 0.0054 16.0 1.6 2.4 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Ribosomal_S28e PF01200.18 ORY78875.1 - 2.5e-30 104.2 0.9 3.8e-30 103.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S7 PF00177.21 ORY78876.1 - 5.5e-38 130.0 2.5 6.8e-38 129.6 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Homeodomain PF00046.29 ORY78878.1 - 7.1e-14 51.4 0.4 1.8e-13 50.1 0.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY78878.1 - 2.9e-06 27.1 0.5 6.5e-06 26.0 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 ORY78878.1 - 0.031 13.7 0.0 0.092 12.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 ORY78879.1 - 2.7e-07 30.4 2.5 4.9e-07 29.5 0.2 2.7 3 0 0 3 3 3 1 Homeobox KN domain Mating_N PF12731.7 ORY78879.1 - 0.0033 17.5 0.0 0.0066 16.5 0.0 1.5 1 0 0 1 1 1 1 Mating-type protein beta 1 ERAP1_C PF11838.8 ORY78879.1 - 0.0091 15.6 0.6 0.15 11.6 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Mito_carr PF00153.27 ORY78880.1 - 4.1e-45 151.6 1.1 3.8e-17 62.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sas10_Utp3 PF04000.15 ORY78884.1 - 5.8e-15 55.7 0.0 5.8e-15 55.7 0.0 2.5 2 1 1 3 3 3 1 Sas10/Utp3/C1D family Rrn6 PF10214.9 ORY78884.1 - 0.028 12.9 2.7 0.032 12.7 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PRP21_like_P PF12230.8 ORY78884.1 - 0.037 13.9 9.0 0.055 13.3 9.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein YL1 PF05764.13 ORY78884.1 - 0.042 14.0 17.6 0.065 13.4 17.6 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PBP1_TM PF14812.6 ORY78884.1 - 0.16 12.4 7.8 0.49 10.8 7.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PI3K_1B_p101 PF10486.9 ORY78884.1 - 0.31 8.8 4.8 0.84 7.3 4.9 1.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleo_P87 PF07267.11 ORY78884.1 - 0.93 8.3 3.7 1.1 8.0 3.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRN3 PF05327.11 ORY78884.1 - 1.1 7.7 3.5 1.7 7.1 3.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GOLD_2 PF13897.6 ORY78884.1 - 2.3 8.7 4.7 4.1 7.9 4.7 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Macoilin PF09726.9 ORY78884.1 - 2.5 6.6 7.8 2.7 6.4 7.8 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 ORY78884.1 - 2.7 6.2 12.8 3.4 5.8 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.12 ORY78884.1 - 3.5 6.5 13.3 4.5 6.2 13.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hid1 PF12722.7 ORY78884.1 - 7.5 4.6 5.6 8.4 4.4 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 ORY78884.1 - 8.1 6.2 10.4 10 5.9 10.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SF3b10 PF07189.11 ORY78885.1 - 4.6e-35 119.6 0.1 5.6e-35 119.3 0.1 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) F-box-like PF12937.7 ORY78886.1 - 0.00024 20.9 1.9 0.00051 19.9 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY78886.1 - 0.38 10.7 7.7 0.083 12.8 2.0 2.7 2 1 0 2 2 2 0 F-box domain SET PF00856.28 ORY78887.1 - 1.4e-06 28.8 0.0 3.5e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 SET domain BUD22 PF09073.10 ORY78888.1 - 1.1e-80 272.1 20.1 1.8e-80 271.4 20.1 1.3 1 0 0 1 1 1 1 BUD22 cNMP_binding PF00027.29 ORY78889.1 - 1.7e-31 108.1 0.0 5.6e-15 55.2 0.0 5.5 5 0 0 5 5 5 5 Cyclic nucleotide-binding domain Patatin PF01734.22 ORY78889.1 - 3.5e-18 66.5 6.7 3e-10 40.6 5.6 2.9 2 0 0 2 2 2 2 Patatin-like phospholipase DUF4519 PF15012.6 ORY78891.1 - 0.46 10.7 1.8 0.73 10.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) Phytochelatin PF05023.14 ORY78892.1 - 3.8e-67 225.6 0.0 1.8e-66 223.4 0.0 1.9 1 1 0 1 1 1 1 Phytochelatin synthase MMM1 PF10296.9 ORY78893.1 - 5e-07 29.1 0.2 4.7e-06 25.9 0.0 2.3 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Soyouz_module PF14313.6 ORY78894.1 - 0.18 11.6 0.1 0.44 10.4 0.1 1.6 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) SNF2_N PF00176.23 ORY78895.1 - 1.8e-63 214.4 0.0 2.9e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY78895.1 - 6.5e-12 45.8 0.1 2.2e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 ORY78895.1 - 0.00028 20.8 1.1 0.00056 19.8 1.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY78895.1 - 0.019 14.8 1.2 0.045 13.6 1.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ORY78895.1 - 0.02 14.8 1.5 0.05 13.5 1.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY78895.1 - 0.04 13.9 0.8 0.17 11.9 0.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger ResIII PF04851.15 ORY78895.1 - 0.05 13.6 0.1 12 5.8 0.1 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 ORY78895.1 - 0.069 13.0 3.0 0.22 11.4 2.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Integrase_1 PF12835.7 ORY78895.1 - 0.074 13.2 0.7 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Integrase TetR_C_18 PF17923.1 ORY78895.1 - 0.098 13.2 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-RING_2 PF13639.6 ORY78895.1 - 0.38 11.1 2.5 0.93 9.9 2.5 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 ORY78895.1 - 0.46 10.4 2.0 1.2 9.1 2.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.25 ORY78896.1 - 3.5e-23 82.1 0.0 6.4e-19 68.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY78896.1 - 1.2e-09 38.1 0.0 5.3e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY78896.1 - 5e-06 26.5 0.1 9.2e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 ORY78897.1 - 1.6e-05 24.9 7.2 3.2e-05 24.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BSP PF04450.12 ORY78898.1 - 2e-57 194.4 0.0 2.3e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Zincin_1 PF06262.11 ORY78898.1 - 0.017 15.2 0.5 0.04 14.0 0.4 1.7 1 1 0 1 1 1 0 Zincin-like metallopeptidase Palm_thioest PF02089.15 ORY78899.1 - 2.8e-06 27.4 0.0 5.5e-06 26.4 0.0 1.5 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 ORY78899.1 - 7.8e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY78899.1 - 0.00045 20.9 0.1 0.00084 20.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY78899.1 - 0.00054 19.7 0.1 0.0091 15.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 ORY78899.1 - 0.00059 19.4 0.0 0.0021 17.6 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.11 ORY78899.1 - 0.0021 17.5 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 ORY78899.1 - 0.014 14.5 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 ORY78899.1 - 0.054 12.7 0.1 0.11 11.8 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORY78899.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Zn_clus PF00172.18 ORY78900.1 - 3.8e-05 23.7 7.8 7.8e-05 22.7 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.27 ORY78901.1 - 4.9e-35 120.8 0.2 2.3e-34 118.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY78901.1 - 9e-20 70.8 0.0 2.5e-19 69.3 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 ORY78901.1 - 2.4e-10 40.6 15.8 4.7e-09 36.5 0.2 4.3 5 0 0 5 5 5 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY78901.1 - 4.7e-06 26.7 0.1 2.8e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Cwf_Cwc_15 PF04889.12 ORY78901.1 - 5.6e-05 23.0 15.9 5.6e-05 23.0 15.9 5.0 2 1 3 5 5 5 1 Cwf15/Cwc15 cell cycle control protein GTP_EFTU_D4 PF14578.6 ORY78901.1 - 0.00022 21.1 0.1 0.0007 19.5 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 ORY78901.1 - 0.00054 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 ORY78901.1 - 0.0037 17.1 0.0 0.015 15.1 0.0 2.1 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 ORY78901.1 - 0.054 13.8 0.8 0.3 11.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain zf_CCCH_4 PF18345.1 ORY78903.1 - 2.5e-07 30.5 12.8 2.4e-06 27.4 2.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORY78903.1 - 3.4e-07 30.0 8.2 8e-06 25.6 1.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY78903.1 - 1e-05 25.2 2.3 1e-05 25.2 2.3 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY78903.1 - 5.1e-05 23.6 15.4 0.00012 22.4 2.9 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY78903.1 - 0.001 19.7 6.2 0.16 12.7 0.0 3.3 3 0 0 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 ORY78903.1 - 0.0012 19.0 0.4 0.27 11.4 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger containing family Form_Nir_trans PF01226.17 ORY78904.1 - 2.1e-68 230.2 16.0 2.5e-68 230.0 16.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DUF2107 PF09880.9 ORY78904.1 - 0.58 10.3 8.9 0.27 11.4 0.6 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2107) F-box-like PF12937.7 ORY78905.1 - 0.031 14.2 0.1 0.097 12.6 0.1 1.9 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 ORY78905.1 - 6.9 7.2 6.8 13 6.4 0.7 3.4 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) SOG2 PF10428.9 ORY78906.1 - 0.52 9.5 12.5 0.0091 15.3 5.7 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein F-box-like PF12937.7 ORY78907.1 - 0.00031 20.6 0.3 0.0008 19.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like RNA_pol_Rpb2_6 PF00562.28 ORY78908.1 - 5.8e-126 420.7 0.1 9.3e-126 420.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY78908.1 - 2e-68 229.9 0.2 3.1e-68 229.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 ORY78908.1 - 2e-46 158.0 0.1 3.4e-46 157.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORY78908.1 - 1.8e-30 105.2 0.4 6.1e-30 103.5 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 ORY78908.1 - 8.3e-26 90.1 1.5 1.6e-25 89.1 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 ORY78908.1 - 1.4e-25 89.3 0.1 4.1e-25 87.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ORY78908.1 - 6.4e-24 84.3 1.0 1.7e-23 82.9 1.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_45 PF10385.9 ORY78908.1 - 0.06 13.6 0.3 0.59 10.4 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Zn_clus PF00172.18 ORY78911.1 - 7.4e-08 32.4 8.6 1.3e-07 31.6 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC22 PF01166.18 ORY78911.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family MFS_1 PF07690.16 ORY78912.1 - 9.9e-30 103.6 32.9 9.9e-30 103.6 32.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily OPA3 PF07047.12 ORY78912.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Amidohydro_2 PF04909.14 ORY78914.1 - 1.6e-36 126.6 0.1 2e-36 126.3 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase CWC25 PF12542.8 ORY78915.1 - 4.7e-25 88.4 0.8 4.7e-25 88.4 0.8 3.5 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 ORY78915.1 - 1.8e-13 50.4 9.7 1.8e-13 50.4 9.7 5.3 6 1 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR WD40 PF00400.32 ORY78917.1 - 3e-11 43.7 9.1 0.0085 16.9 0.1 5.6 4 1 1 5 5 5 3 WD domain, G-beta repeat Pkinase PF00069.25 ORY78918.1 - 1e-70 238.1 0.0 1.6e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY78918.1 - 1.5e-47 162.1 0.0 2.1e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY78918.1 - 0.0002 20.8 0.0 0.0051 16.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY78918.1 - 0.00038 19.3 0.0 0.00077 18.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 ORY78918.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RTTN_N PF14726.6 ORY78918.1 - 0.11 13.3 1.5 0.36 11.7 0.1 2.6 3 0 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning MRI PF15325.6 ORY78918.1 - 1.1 10.3 7.8 0.29 12.2 2.8 2.6 2 0 0 2 2 2 0 Modulator of retrovirus infection Exonuc_X-T_C PF08411.10 ORY78919.1 - 0.17 11.0 2.0 0.18 10.9 0.4 1.7 2 0 0 2 2 2 0 Exonuclease C-terminal DUF2388 PF09498.10 ORY78920.1 - 0.021 14.8 0.3 0.14 12.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2388) FGGY_C PF02782.16 ORY78921.1 - 2.4e-47 161.2 0.0 3.3e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY78921.1 - 1.7e-21 76.9 1.1 7.7e-19 68.2 1.1 3.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 ORY78921.1 - 1.4e-06 28.0 0.3 0.00017 21.2 0.1 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.21 ORY78921.1 - 0.057 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Hexokinase MFS_1 PF07690.16 ORY78923.1 - 3.3e-17 62.5 42.2 3.7e-17 62.3 37.3 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4965 PF16335.5 ORY78924.1 - 2e-75 252.2 0.5 3.6e-75 251.4 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 ORY78924.1 - 9.9e-65 218.5 0.1 1.7e-64 217.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 ORY78924.1 - 3.5e-57 193.5 0.6 5.6e-57 192.8 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydr_116N PF12215.8 ORY78924.1 - 0.00048 19.7 0.1 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4964 PF16334.5 ORY78924.1 - 0.022 14.3 0.4 0.096 12.3 0.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4964) SURF2 PF05477.11 ORY78927.1 - 0.036 13.8 7.3 0.067 12.9 7.3 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 ORY78927.1 - 0.064 11.6 1.9 0.091 11.0 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SEEEED PF14797.6 ORY78927.1 - 0.21 11.8 33.9 0.53 10.5 33.9 1.6 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Apt1 PF10351.9 ORY78927.1 - 0.95 8.2 12.7 1.6 7.5 12.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain YL1 PF05764.13 ORY78927.1 - 3.1 7.9 11.5 0.2 11.7 5.4 1.9 2 0 0 2 2 2 0 YL1 nuclear protein SnoaL_2 PF12680.7 ORY78928.1 - 0.00016 22.3 0.3 0.00021 21.9 0.3 1.3 1 0 0 1 1 1 1 SnoaL-like domain RRM_1 PF00076.22 ORY78930.1 - 5.6e-28 96.6 0.0 3.6e-08 33.1 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 ORY78930.1 - 0.011 15.6 0.0 0.092 12.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) ADH_N PF08240.12 ORY79258.1 - 1.1e-24 86.4 0.2 2.8e-24 85.1 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY79258.1 - 1.7e-21 76.5 0.9 3.1e-21 75.7 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY79258.1 - 4.1e-05 24.6 0.1 9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sec63 PF02889.16 ORY79259.1 - 4.8e-163 540.4 0.0 7.3e-90 300.6 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORY79259.1 - 5.2e-45 153.4 0.9 8.6e-26 90.8 0.1 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 ORY79259.1 - 1.3e-32 112.2 0.1 4.4e-32 110.5 0.1 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 ORY79259.1 - 5.2e-22 78.6 0.1 3.4e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY79259.1 - 3e-14 53.3 0.1 2.7e-08 34.1 0.0 3.8 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY79259.1 - 6.2e-05 23.3 0.5 0.23 11.7 0.0 4.1 4 2 0 4 4 4 2 AAA domain AAA_30 PF13604.6 ORY79259.1 - 0.00016 21.4 0.3 0.45 10.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain PhoH PF02562.16 ORY79259.1 - 0.00033 20.2 0.0 0.0095 15.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 ORY79259.1 - 0.0086 15.2 0.0 0.66 9.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF603 PF04645.12 ORY79259.1 - 0.028 14.1 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Helicase_C_2 PF13307.6 ORY79259.1 - 0.11 12.7 0.0 11 6.1 0.0 3.4 3 1 1 4 4 4 0 Helicase C-terminal domain TFIIE_alpha PF02002.17 ORY79259.1 - 0.28 11.1 2.1 7.6 6.5 0.1 3.0 3 0 0 3 3 3 0 TFIIE alpha subunit PRKCSH PF07915.13 ORY79260.1 - 4.2e-14 53.3 0.0 1.1e-13 52.0 0.0 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 ORY79260.1 - 0.027 14.2 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Aminotran_1_2 PF00155.21 ORY79261.1 - 4.5e-86 289.3 0.0 5.1e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II p450 PF00067.22 ORY79262.1 - 1.1e-59 202.5 0.0 1e-58 199.2 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 EF-hand_1 PF00036.32 ORY79263.1 - 1.6e-17 61.7 14.6 1.2e-08 33.9 0.2 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ORY79263.1 - 7.8e-16 57.7 4.3 8.2e-09 35.2 1.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 ORY79263.1 - 1.7e-15 57.2 4.5 2.2e-07 31.2 0.9 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY79263.1 - 4.2e-15 54.3 5.8 6e-07 28.9 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 ORY79263.1 - 8.2e-10 37.7 11.2 3.2e-06 26.4 0.1 4.0 4 1 1 5 5 5 2 EF hand EF-hand_4 PF12763.7 ORY79263.1 - 2.3e-08 33.9 1.8 0.00081 19.3 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY79263.1 - 0.0015 18.8 0.3 0.15 12.4 0.0 2.6 2 1 1 3 3 3 1 EF-hand domain Caleosin PF05042.13 ORY79263.1 - 0.011 15.7 0.3 0.12 12.2 0.0 2.2 2 1 0 2 2 2 0 Caleosin related protein Dockerin_1 PF00404.18 ORY79263.1 - 0.038 14.2 0.1 7.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain DUF3741 PF12552.8 ORY79263.1 - 0.07 13.1 0.5 5.8 7.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) SPARC_Ca_bdg PF10591.9 ORY79263.1 - 0.073 13.4 0.1 7.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UQ_con PF00179.26 ORY79264.1 - 1.9e-44 150.7 0.0 2.2e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY79264.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 ORY79264.1 - 0.064 13.1 0.1 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 ORY79264.1 - 0.069 13.4 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF726 PF05277.12 ORY79265.1 - 1e-120 402.8 2.8 1.4e-120 402.3 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lin-8 PF03353.15 ORY79265.1 - 1.7 8.1 6.7 0.44 10.1 2.7 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist COX2_TM PF02790.15 ORY79267.1 - 0.4 10.9 3.5 2.3 8.4 0.0 2.9 2 1 1 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Polysacc_synt_C PF14667.6 ORY79267.1 - 2.8 8.0 19.5 0.66 10.0 10.0 2.8 1 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Thiolase_N PF00108.23 ORY79268.1 - 8.9e-74 248.1 0.0 1.9e-73 247.0 0.0 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY79268.1 - 2.6e-47 159.5 0.5 1.5e-46 157.0 0.2 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY79268.1 - 0.0024 17.5 0.2 0.01 15.4 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ORY79268.1 - 0.073 13.2 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal FTA4 PF13093.6 ORY79269.1 - 0.0094 15.9 0.8 0.0094 15.9 0.8 1.4 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BLOC1_2 PF10046.9 ORY79269.1 - 0.065 13.5 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PTPRCAP PF15713.5 ORY79269.1 - 1.4 9.1 9.5 0.13 12.6 2.2 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Pox_Ag35 PF03286.14 ORY79269.1 - 7.7 6.3 17.8 2.7 7.7 0.6 2.4 2 1 0 2 2 2 0 Pox virus Ag35 surface protein BRCA-2_OB1 PF09103.10 ORY79270.1 - 2.9e-32 111.2 0.0 4.4e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 ORY79270.1 - 1.6e-10 40.5 1.3 0.00032 20.3 0.0 4.3 4 0 0 4 4 4 3 BRCA2 repeat BRCA-2_helical PF09169.10 ORY79270.1 - 2.6e-10 40.3 0.1 6.9e-10 38.9 0.1 1.6 1 1 0 2 2 2 1 BRCA2, helical Bac_luciferase PF00296.20 ORY79270.1 - 0.0021 17.6 0.2 0.0054 16.2 0.2 1.6 1 0 0 1 1 1 1 Luciferase-like monooxygenase Ist1 PF03398.14 ORY79271.1 - 4.8e-58 195.7 0.2 6.4e-58 195.3 0.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ribosomal_60s PF00428.19 ORY79271.1 - 7.7 7.2 9.9 0.3 11.7 3.0 2.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein BTB PF00651.31 ORY79272.1 - 0.039 14.2 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain SR-25 PF10500.9 ORY79273.1 - 0.84 9.2 16.8 0.51 9.9 1.9 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DASH_Ask1 PF08655.10 ORY79274.1 - 3.4e-23 81.3 0.3 6.4e-23 80.4 0.3 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 SRF-TF PF00319.18 ORY79275.1 - 1.1e-20 72.8 0.1 1.8e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Peptidase_S10 PF00450.22 ORY79276.1 - 3e-116 389.3 1.2 3.5e-116 389.0 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF953 PF06110.11 ORY79277.1 - 6.7e-20 70.9 0.0 8e-20 70.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.6 ORY79277.1 - 0.0063 16.7 0.0 0.0093 16.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY79277.1 - 0.04 14.4 0.1 0.25 11.8 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 ORY79277.1 - 0.047 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_9 PF14595.6 ORY79277.1 - 0.082 12.7 0.1 0.1 12.4 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.6 ORY79277.1 - 0.18 12.2 0.0 0.96 9.8 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like zf-MYND PF01753.18 ORY79278.1 - 2e-10 40.6 12.7 3.1e-10 39.9 12.7 1.3 1 0 0 1 1 1 1 MYND finger Ferritin PF00210.24 ORY79278.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain zf-MYND PF01753.18 ORY79279.1 - 4.6e-09 36.2 9.1 8.6e-09 35.3 9.1 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY79279.1 - 0.019 15.3 4.9 0.033 14.5 4.9 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ribosomal_S21 PF01165.20 ORY79280.1 - 6.9e-13 48.1 6.0 1.1e-12 47.5 6.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 Prefoldin_2 PF01920.20 ORY79281.1 - 1.4e-19 70.0 0.6 1.6e-19 69.8 0.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit Uds1 PF15456.6 ORY79281.1 - 0.011 16.0 0.6 0.014 15.5 0.6 1.2 1 0 0 1 1 1 0 Up-regulated During Septation DUF5320 PF17253.2 ORY79281.1 - 0.061 14.4 0.5 0.12 13.4 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) polyprenyl_synt PF00348.17 ORY79282.1 - 6e-65 218.8 0.0 6.7e-58 195.7 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase DUF776 PF05604.11 ORY79282.1 - 0.13 12.7 1.2 0.22 11.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF776) YjeF_N PF03853.15 ORY79283.1 - 1.5e-35 122.6 0.0 1.8e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Calreticulin PF00262.18 ORY79284.1 - 5.8e-163 542.0 5.3 7.7e-163 541.6 5.3 1.1 1 0 0 1 1 1 1 Calreticulin family DUF948 PF06103.11 ORY79284.1 - 0.24 11.7 2.5 0.61 10.4 2.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 ORY79284.1 - 0.76 9.6 9.9 0.078 12.8 5.3 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain NAM-associated PF14303.6 ORY79285.1 - 1.6 9.4 3.5 2.3 8.9 3.5 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF2417 PF10329.9 ORY79286.1 - 5.7e-15 55.4 0.2 8.1e-15 54.9 0.2 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) CitMHS PF03600.16 ORY79286.1 - 0.77 8.9 12.9 0.8 8.8 11.2 1.6 1 1 0 1 1 1 0 Citrate transporter PhoD PF09423.10 ORY79287.1 - 1.7e-34 119.4 0.3 5.1e-34 117.8 0.3 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase DUF1338 PF07063.13 ORY79288.1 - 4.2e-100 335.1 0.0 5e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) ATP1G1_PLM_MAT8 PF02038.16 ORY79288.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family AA_permease PF00324.21 ORY79289.1 - 1.5e-123 412.9 39.9 1.9e-123 412.6 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY79289.1 - 2.2e-37 128.9 43.8 3.1e-37 128.4 43.8 1.2 1 0 0 1 1 1 1 Amino acid permease DFP PF04127.15 ORY79290.1 - 5.7e-17 62.2 0.0 1.7e-09 37.8 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RCC1 PF00415.18 ORY79291.1 - 2.5e-29 101.6 7.2 1.4e-05 25.6 0.1 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY79291.1 - 1.7e-18 65.9 14.4 8e-06 25.5 0.1 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Oxidored_q3 PF00499.20 ORY79292.1 - 0.0037 17.0 3.2 0.0037 17.0 3.2 1.7 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SdpI PF13630.6 ORY79292.1 - 0.55 10.4 11.9 7.5 6.8 0.0 3.7 4 0 0 4 4 4 0 SdpI/YhfL protein family DHHC PF01529.20 ORY79292.1 - 1.4 9.1 4.0 4.3 7.5 1.0 2.1 1 1 0 2 2 2 0 DHHC palmitoyltransferase zf-C2H2 PF00096.26 ORY79293.1 - 6.8e-10 38.8 9.8 1.4e-05 25.2 1.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY79293.1 - 9.3e-07 29.0 9.7 2.7e-05 24.4 1.0 3.5 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 ORY79293.1 - 2.1e-06 28.3 2.6 0.015 15.9 0.4 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY79293.1 - 1.5e-05 25.4 10.0 0.02 15.7 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY79293.1 - 0.038 14.3 0.7 0.19 12.1 0.7 2.0 1 1 0 1 1 1 0 C2H2-type zinc ribbon Ogr_Delta PF04606.12 ORY79293.1 - 0.076 13.0 0.1 17 5.5 0.1 2.6 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 ORY79293.1 - 0.079 13.3 0.1 21 5.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY79293.1 - 0.2 11.8 1.2 3.8 7.6 0.2 2.1 1 1 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORY79293.1 - 2.4 8.0 9.0 9.2 6.1 1.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 ORY79293.1 - 3.4 7.5 5.2 3.8 7.4 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-MYND PF01753.18 ORY79294.1 - 4.6e-11 42.6 15.5 1e-10 41.5 15.5 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY79294.1 - 0.081 13.2 10.0 0.24 11.8 10.0 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DHHC PF01529.20 ORY79295.1 - 5.9e-33 113.8 12.9 5.9e-33 113.8 12.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.6 ORY79295.1 - 0.068 13.1 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Bromodomain PF00439.25 ORY79296.1 - 2.2e-32 111.0 0.5 3.2e-16 59.1 0.1 2.3 2 0 0 2 2 2 2 Bromodomain RAP1 PF07218.11 ORY79296.1 - 0.24 9.7 0.0 0.34 9.1 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CUE PF02845.16 ORY79297.1 - 8.2e-11 41.4 0.0 1.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 CUE domain FXMRP1_C_core PF12235.8 ORY79297.1 - 0.0098 16.5 2.1 0.02 15.6 0.2 2.0 2 0 0 2 2 2 1 Fragile X-related 1 protein core C terminal DNA_pol_B_palm PF14792.6 ORY79298.1 - 4.6e-22 78.4 0.1 1e-21 77.3 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ORY79298.1 - 6.5e-19 67.9 0.0 1.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ORY79298.1 - 4.1e-14 52.1 0.1 9.3e-14 51.0 0.1 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ORY79298.1 - 3.1e-07 30.7 0.1 6.1e-06 26.5 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 ORY79298.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Acetyltransf_1 PF00583.25 ORY79299.1 - 1.3e-05 25.4 0.0 6.2e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY79299.1 - 0.0035 17.8 0.0 0.0053 17.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY79299.1 - 0.057 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ORY79299.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C3HC4 PF00097.25 ORY79300.1 - 2.7e-09 36.7 6.4 4.2e-09 36.1 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY79300.1 - 2.6e-08 33.6 5.0 4.4e-08 32.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY79300.1 - 2.2e-07 31.1 6.4 4.4e-07 30.1 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY79300.1 - 2.2e-07 30.6 7.7 6.8e-07 29.0 8.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY79300.1 - 4e-07 30.0 3.5 4e-07 30.0 3.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY79300.1 - 4.6e-06 26.5 6.0 8.4e-06 25.7 6.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY79300.1 - 0.00045 20.0 4.4 0.00086 19.1 4.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY79300.1 - 0.0016 18.5 7.5 0.003 17.7 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TerY_C PF15616.6 ORY79300.1 - 0.024 14.7 1.1 0.047 13.8 1.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain FYVE PF01363.21 ORY79300.1 - 0.047 13.8 1.3 0.094 12.9 1.3 1.5 1 0 0 1 1 1 0 FYVE zinc finger Rbsn PF11464.8 ORY79300.1 - 0.12 12.2 1.0 0.28 10.9 1.0 1.7 1 0 0 1 1 1 0 Rabenosyn Rab binding domain zf-Nse PF11789.8 ORY79300.1 - 0.13 12.1 1.9 0.27 11.1 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ACC PF17848.1 ORY79300.1 - 0.15 12.2 3.2 0.096 12.8 0.9 1.9 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-ANAPC11 PF12861.7 ORY79300.1 - 0.25 11.4 2.5 0.47 10.5 2.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 ORY79300.1 - 0.27 11.0 9.5 0.68 9.7 9.5 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 ORY79300.1 - 0.35 10.7 5.6 0.43 10.4 3.6 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_6 PF14835.6 ORY79300.1 - 0.58 10.1 1.9 1.3 8.9 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY79300.1 - 0.84 10.0 5.9 1.8 8.9 5.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Rrn6 PF10214.9 ORY79300.1 - 0.96 7.9 5.1 1.5 7.2 5.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Acetyltransf_7 PF13508.7 ORY79301.1 - 6.2e-05 23.4 0.0 0.00013 22.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY79301.1 - 0.0029 17.8 0.2 0.0077 16.5 0.1 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_15 PF17013.5 ORY79301.1 - 0.0099 15.4 0.2 0.027 14.0 0.1 1.9 1 1 1 2 2 2 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 ORY79301.1 - 0.027 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 ORY79301.1 - 0.048 13.6 0.0 0.56 10.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GMC_oxred_N PF00732.19 ORY79302.1 - 6.8e-62 209.5 0.0 9.9e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY79302.1 - 4.1e-32 111.7 0.0 7.6e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY79302.1 - 0.00032 20.9 1.0 0.00091 19.4 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY79302.1 - 0.00074 18.7 0.5 0.0014 17.8 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY79302.1 - 0.0011 18.3 0.3 0.0024 17.1 0.3 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 ORY79302.1 - 0.0014 17.8 7.8 0.066 12.3 2.2 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY79302.1 - 0.0017 17.7 0.2 0.0039 16.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY79302.1 - 0.0017 18.0 2.6 0.0093 15.6 1.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY79302.1 - 0.021 14.1 0.6 0.32 10.2 0.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CHB_HEX_C PF03174.13 ORY79302.1 - 0.035 14.1 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF515 PF04415.12 ORY79302.1 - 6.2 5.1 8.3 12 4.1 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Aldedh PF00171.22 ORY79303.1 - 1.5e-129 432.5 0.0 1.8e-129 432.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY79303.1 - 0.13 11.3 0.0 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Ribosomal_S9 PF00380.19 ORY79305.1 - 1.8e-30 105.9 0.0 2.1e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 F-box-like PF12937.7 ORY79306.1 - 0.0011 18.8 0.5 0.0032 17.3 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY79306.1 - 0.0021 17.9 1.3 0.014 15.2 1.3 2.5 1 1 0 1 1 1 1 F-box domain V-SNARE_C PF12352.8 ORY79307.1 - 4.6e-14 52.4 0.3 1.6e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus HBM PF16591.5 ORY79307.1 - 0.011 15.2 0.5 0.011 15.2 0.5 2.0 2 1 0 3 3 3 0 Helical bimodular sensor domain Syntaxin-6_N PF09177.11 ORY79307.1 - 0.17 12.5 2.4 0.52 10.9 0.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 ORY79307.1 - 0.3 11.1 7.8 1.7 8.7 0.1 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nop14 PF04147.12 ORY79308.1 - 0.56 8.3 12.9 0.61 8.2 12.9 1.0 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 ORY79308.1 - 0.66 9.6 4.5 0.66 9.6 4.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 ORY79308.1 - 2.2 6.5 12.1 2.7 6.2 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 ORY79308.1 - 4.8 6.4 12.7 4.9 6.4 12.7 1.2 1 0 0 1 1 1 0 BUD22 zf-U1 PF06220.12 ORY79309.1 - 1.2e-09 37.7 0.9 1.9e-09 37.1 0.9 1.3 1 0 0 1 1 1 1 U1 zinc finger ABC_tran_Xtn PF12848.7 ORY79309.1 - 0.011 15.7 1.2 0.011 15.7 1.2 3.0 3 0 0 3 3 3 0 ABC transporter Peptidase_M24 PF00557.24 ORY79310.1 - 1.3e-39 136.0 0.0 1.7e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_L34e PF01199.18 ORY79311.1 - 4.5e-43 145.5 5.2 6.1e-43 145.0 5.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 ORY79311.1 - 0.03 14.3 1.1 4.8 7.2 0.1 2.6 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Cytochrome_C7 PF14522.6 ORY79311.1 - 0.047 13.7 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF1428 PF07237.11 ORY79311.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) PPR_2 PF13041.6 ORY79312.1 - 2e-10 40.7 0.0 0.00014 22.0 0.0 4.4 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.20 ORY79312.1 - 2.5e-07 30.5 4.2 2.3 8.7 0.1 6.6 6 1 0 6 6 6 3 PPR repeat PPR_long PF17177.4 ORY79312.1 - 4e-07 29.6 0.0 0.00018 21.0 0.0 2.5 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP ERAP1_C PF11838.8 ORY79312.1 - 0.00022 20.9 0.0 0.57 9.7 0.0 2.6 2 0 0 2 2 2 2 ERAP1-like C-terminal domain PPR_3 PF13812.6 ORY79312.1 - 0.065 13.3 0.0 4.3 7.5 0.0 3.5 3 1 2 5 5 5 0 Pentatricopeptide repeat domain TIP49 PF06068.13 ORY79315.1 - 1.1e-156 521.4 2.4 1.4e-156 521.1 2.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY79315.1 - 1.4e-26 92.4 0.5 1.2e-25 89.5 0.3 2.5 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 ORY79315.1 - 2.8e-09 37.5 0.5 6.2e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY79315.1 - 3.4e-07 30.1 0.5 0.00059 19.6 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 ORY79315.1 - 9.6e-07 28.4 0.9 1.9e-06 27.4 0.9 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 ORY79315.1 - 2.7e-05 24.6 0.1 0.00032 21.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 ORY79315.1 - 0.00041 19.8 1.2 0.019 14.3 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORY79315.1 - 0.0014 18.2 0.1 0.022 14.3 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 ORY79315.1 - 0.0016 18.4 0.9 1.4 8.9 0.1 3.7 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY79315.1 - 0.0044 17.3 0.2 0.094 13.0 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY79315.1 - 0.013 15.6 0.0 2.3 8.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 ORY79315.1 - 0.022 15.1 2.2 0.45 10.8 2.2 2.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY79315.1 - 0.027 14.2 0.1 5.9 6.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 ORY79315.1 - 0.032 14.4 0.2 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY79315.1 - 0.13 11.7 1.6 0.49 9.9 0.0 2.6 4 0 0 4 4 4 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 ORY79315.1 - 0.18 10.8 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Gcd10p PF04189.13 ORY79316.1 - 4.3e-71 239.5 0.0 1.1e-70 238.1 0.0 1.7 1 1 0 1 1 1 1 Gcd10p family adh_short_C2 PF13561.6 ORY79317.1 - 1.4e-39 136.1 1.0 5.3e-38 130.9 1.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY79317.1 - 1.3e-35 122.7 2.4 5.2e-35 120.7 2.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY79317.1 - 1.2e-11 44.8 0.1 2e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ORY79317.1 - 0.00026 20.1 0.2 0.00038 19.5 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY79317.1 - 0.00066 19.2 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY79317.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY79317.1 - 0.15 12.0 0.9 0.29 11.0 0.7 1.5 1 1 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 ORY79317.1 - 0.15 11.4 0.2 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 ORY79318.1 - 4.6e-48 163.9 0.0 5.6e-46 157.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MRP-L27 PF09809.9 ORY79318.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 DUF5615 PF18480.1 ORY79318.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) AA_permease PF00324.21 ORY79319.1 - 4.2e-137 457.6 39.9 4.8e-137 457.4 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY79319.1 - 5.1e-44 150.8 44.1 6.9e-44 150.3 44.1 1.2 1 0 0 1 1 1 1 Amino acid permease YpmT PF17431.2 ORY79319.1 - 0.4 10.7 2.9 1.5 8.9 2.9 2.0 1 0 0 1 1 1 0 Uncharacterized YmpT-like RabGAP-TBC PF00566.18 ORY79321.1 - 1.8e-32 112.7 0.2 2.6e-15 56.7 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PAP2 PF01569.21 ORY79321.1 - 0.034 13.9 0.2 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 PAP2 superfamily UCH_1 PF13423.6 ORY79322.1 - 1.5e-86 291.0 0.0 1.9e-86 290.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 ORY79322.1 - 1.4e-20 74.5 0.0 4.1e-20 73.0 0.0 1.8 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 ORY79322.1 - 0.012 15.2 0.0 0.099 12.1 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Vps36-NZF-N PF16988.5 ORY79322.1 - 0.14 11.5 0.1 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Zn_clus PF00172.18 ORY79323.1 - 6.8e-07 29.3 8.4 1.2e-06 28.5 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY79323.1 - 0.00032 19.8 0.1 0.00071 18.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ssDNA_TraI_N PF18272.1 ORY79323.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain HSP20 PF00011.21 ORY79324.1 - 2.2e-14 53.4 0.0 2.7e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY79324.1 - 2.5e-05 23.7 0.0 4.4e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 ORY79324.1 - 0.1 12.7 0.0 11 6.1 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal DHDPS PF00701.22 ORY79325.1 - 2.3e-28 98.7 0.0 3e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Ank_4 PF13637.6 ORY79326.1 - 2e-15 56.9 0.0 1.6e-07 31.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY79326.1 - 5.2e-11 42.6 0.0 1.3e-08 35.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY79326.1 - 9.1e-09 35.8 0.0 2.7e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY79326.1 - 8.1e-08 32.0 0.0 1.2e-05 25.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 ORY79326.1 - 4.3e-06 26.9 0.0 3.9e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat PKD_channel PF08016.12 ORY79327.1 - 3.6e-05 22.6 7.9 0.00019 20.3 0.1 2.1 2 0 0 2 2 2 2 Polycystin cation channel Sugarporin_N PF11471.8 ORY79327.1 - 0.13 12.2 1.0 2 8.5 0.1 2.8 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension adh_short_C2 PF13561.6 ORY79328.1 - 4.7e-52 176.9 0.5 4.1e-51 173.8 0.5 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY79328.1 - 1.5e-46 158.3 1.1 8.9e-46 155.8 1.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY79328.1 - 2.6e-09 37.2 0.9 4.1e-09 36.6 0.1 1.6 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 ORY79328.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Epimerase PF01370.21 ORY79328.1 - 0.02 14.3 0.3 0.056 12.9 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ORY79328.1 - 0.031 13.6 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 ORY79328.1 - 0.057 13.4 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.13 ORY79328.1 - 0.15 11.6 0.2 0.39 10.2 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY79328.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MR_MLE_C PF13378.6 ORY79329.1 - 4.9e-58 196.3 0.0 6.2e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ORY79329.1 - 7.9e-19 68.0 0.0 1.5e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain HEAT_2 PF13646.6 ORY79329.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats Pkinase PF00069.25 ORY79330.1 - 1.2e-55 188.8 0.0 1.5e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY79330.1 - 2.9e-21 75.9 0.1 4.5e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY79330.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY79330.1 - 0.019 14.3 0.0 0.91 8.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 ORY79330.1 - 0.019 14.6 0.0 0.053 13.1 0.0 1.7 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 ORY79330.1 - 0.022 14.4 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 ORY79330.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Rot1 PF10681.9 ORY79332.1 - 9.9e-46 155.9 2.2 1.1e-45 155.7 2.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Peptidase_S8 PF00082.22 ORY79333.1 - 2.4e-44 151.8 5.9 4.3e-44 151.0 5.9 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 ORY79333.1 - 1.4e-06 28.2 0.0 4.4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 PA domain fn3_5 PF06280.12 ORY79333.1 - 2.1e-05 25.2 0.0 4.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain Y_Y_Y PF07495.13 ORY79333.1 - 0.0062 16.5 0.1 0.02 14.8 0.1 1.8 2 0 0 2 2 2 1 Y_Y_Y domain Ost4 PF10215.9 ORY79334.1 - 0.0011 18.8 2.0 0.0017 18.2 2.0 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase zf-RING_10 PF16685.5 ORY79335.1 - 1.4e-05 25.1 1.3 3e-05 24.1 1.3 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 ORY79335.1 - 0.00012 21.9 4.4 0.00022 21.1 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY79335.1 - 0.0006 19.6 6.5 0.00066 19.5 3.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY79335.1 - 0.0012 18.7 2.4 0.0012 18.7 2.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY79335.1 - 0.016 15.0 3.3 0.031 14.1 3.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY79335.1 - 0.17 12.0 3.2 0.4 10.7 3.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY79335.1 - 0.17 11.7 8.2 0.5 10.3 8.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY79335.1 - 0.24 11.8 3.4 0.57 10.6 3.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 ORY79335.1 - 0.59 10.3 6.1 0.19 11.9 2.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RanBP PF00641.18 ORY79335.1 - 1.3 8.4 6.7 0.54 9.6 2.6 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Aldo_ket_red PF00248.21 ORY79337.1 - 2.9e-47 161.3 0.0 3.6e-45 154.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF5615 PF18480.1 ORY79337.1 - 0.16 11.7 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) adh_short_C2 PF13561.6 ORY79338.1 - 1.4e-39 136.1 1.0 5.3e-38 130.9 1.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY79338.1 - 1.3e-35 122.7 2.4 5.2e-35 120.7 2.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY79338.1 - 1.2e-11 44.8 0.1 2e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 ORY79338.1 - 0.00026 20.1 0.2 0.00038 19.5 0.2 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY79338.1 - 0.00066 19.2 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY79338.1 - 0.011 15.1 0.1 0.02 14.3 0.1 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY79338.1 - 0.15 12.0 0.9 0.29 11.0 0.7 1.5 1 1 0 1 1 1 0 NAD(P)H-binding 2-Hacid_dh_C PF02826.19 ORY79338.1 - 0.15 11.4 0.2 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4536 PF15055.6 ORY79339.1 - 1.9e-06 28.0 4.2 6.8e-06 26.2 4.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) W2 PF02020.18 ORY79340.1 - 1.5e-09 37.9 0.5 4e-09 36.5 0.5 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 ORY79340.1 - 3.6e-09 36.0 3.3 0.00018 21.1 0.9 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 ORY79340.1 - 0.00046 19.3 2.0 0.08 11.9 0.9 2.1 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 ORY79340.1 - 0.13 12.6 0.0 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY79340.1 - 0.13 12.0 10.4 1.1 9.0 2.3 3.5 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORY79340.1 - 0.26 9.4 0.6 0.39 8.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) PFK PF00365.20 ORY79341.1 - 2.2e-188 624.4 3.2 1.6e-106 355.8 1.1 3.0 2 1 0 2 2 2 2 Phosphofructokinase SHOCT PF09851.9 ORY79341.1 - 0.059 13.1 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Short C-terminal domain DAGK_cat PF00781.24 ORY79341.1 - 0.11 12.1 0.3 0.68 9.6 0.2 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Ras PF00071.22 ORY79342.1 - 2e-57 193.3 0.2 2.4e-57 193.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY79342.1 - 1.1e-19 70.7 0.0 1.8e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY79342.1 - 7.5e-09 35.3 0.0 9.3e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY79342.1 - 3.6e-05 23.4 0.0 5.7e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY79342.1 - 0.00022 21.1 0.1 0.43 10.5 0.0 2.3 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 ORY79342.1 - 0.0033 17.4 0.0 0.0074 16.3 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORY79342.1 - 0.023 14.8 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY79342.1 - 0.027 14.0 0.0 0.064 12.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 ORY79342.1 - 0.037 13.4 0.1 0.052 12.9 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Protoglobin PF11563.8 ORY79343.1 - 1.1e-31 109.9 0.0 1.4e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protoglobin T2SSF PF00482.23 ORY79344.1 - 0.15 12.0 2.2 0.28 11.1 2.2 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Solute_trans_a PF03619.16 ORY79345.1 - 1.7e-78 263.8 13.0 2.1e-78 263.5 13.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CAP_N PF01213.19 ORY79346.1 - 0.52 9.7 4.7 0.85 9.0 4.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Fes1 PF08609.10 ORY79347.1 - 1.2e-22 80.5 0.2 3.3e-22 79.2 0.2 1.8 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 V-ATPase_H_N PF03224.14 ORY79347.1 - 2.4e-05 23.8 0.8 0.069 12.4 0.0 2.2 1 1 1 2 2 2 2 V-ATPase subunit H HEAT PF02985.22 ORY79347.1 - 6e-05 23.0 3.2 0.44 10.9 0.1 4.2 4 1 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 ORY79347.1 - 0.0008 19.7 0.0 1.7 9.1 0.0 2.7 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 ORY79347.1 - 0.013 16.0 2.9 2.2 8.9 0.1 4.1 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.7 ORY79347.1 - 0.016 15.3 0.0 0.24 11.4 0.0 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 ORY79347.1 - 0.12 12.5 2.4 3.5 7.8 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4097 PF13349.6 ORY79348.1 - 0.0051 16.2 0.6 0.068 12.5 0.6 2.2 1 1 0 1 1 1 1 Putative adhesin FMO-like PF00743.19 ORY79349.1 - 7.3e-15 54.4 0.0 6.2e-13 48.0 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY79349.1 - 1.1e-13 51.1 0.1 9.1e-11 41.5 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY79349.1 - 8.7e-13 48.1 0.0 1.9e-10 40.5 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY79349.1 - 1.7e-09 37.3 0.1 4.1e-06 26.2 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 ORY79349.1 - 2.9e-05 24.2 0.0 8.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY79349.1 - 0.00015 21.2 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY79349.1 - 0.0011 18.6 0.0 0.08 12.5 0.0 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY79349.1 - 0.0032 16.6 0.3 0.041 13.0 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 ORY79349.1 - 0.0035 16.7 0.0 0.0088 15.4 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ORY79349.1 - 0.004 17.7 0.0 0.25 11.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY79349.1 - 0.02 13.6 0.0 0.056 12.2 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.6 ORY79349.1 - 0.029 14.4 0.0 6.3 6.8 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 ORY79349.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 ORY79349.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 ORY79349.1 - 0.15 12.6 0.0 0.37 11.3 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Pkinase PF00069.25 ORY79350.1 - 3.6e-48 164.2 0.0 7.4e-31 107.5 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY79350.1 - 1.7e-23 83.3 0.0 2.1e-19 69.8 0.0 3.2 4 0 0 4 4 4 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY79350.1 - 0.00036 19.4 0.8 0.00063 18.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY79350.1 - 0.0018 18.2 0.1 0.026 14.4 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family ABC2_membrane PF01061.24 ORY79351.1 - 2.8e-35 121.6 18.0 2.8e-35 121.6 18.0 2.4 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.27 ORY79351.1 - 1.5e-27 96.7 0.1 2.5e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORY79351.1 - 1.4e-05 24.4 19.3 3.3e-05 23.2 19.3 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORY79351.1 - 3e-05 24.0 0.5 0.091 12.5 0.2 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system EGF_2 PF07974.13 ORY79351.1 - 0.00013 22.2 21.2 0.00052 20.3 10.3 3.3 2 0 0 2 2 2 1 EGF-like domain SMC_N PF02463.19 ORY79351.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY79351.1 - 0.0032 17.2 0.1 0.0079 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain EGF_Tenascin PF18720.1 ORY79351.1 - 0.0038 17.2 3.6 0.0038 17.2 3.6 3.3 5 0 0 5 5 1 1 Tenascin EGF domain RsgA_GTPase PF03193.16 ORY79351.1 - 0.0089 15.9 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 ORY79351.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY79351.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY79351.1 - 0.072 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Calici_MSP PF05752.11 ORY79351.1 - 0.098 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Calicivirus minor structural protein AAA_25 PF13481.6 ORY79351.1 - 0.15 11.6 0.1 0.41 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain hEGF PF12661.7 ORY79351.1 - 0.37 11.5 23.3 0.043 14.5 7.9 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF ABC2_membrane_2 PF12679.7 ORY79351.1 - 3.4 6.9 16.4 1.5e+02 1.4 16.4 2.5 1 1 0 1 1 1 0 ABC-2 family transporter protein AMP-binding PF00501.28 ORY79352.1 - 5.5e-76 255.9 0.0 6.5e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY79352.1 - 4.3e-17 62.9 0.1 1e-16 61.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DNA_pol_B_palm PF14792.6 ORY79353.1 - 2.6e-26 92.1 0.0 5.9e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ORY79353.1 - 1.4e-22 79.6 0.1 4.1e-22 78.1 0.1 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ORY79353.1 - 7.8e-14 51.2 0.0 5.6e-13 48.5 0.0 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ORY79353.1 - 2.4e-12 47.0 1.4 5.3e-12 45.9 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 ORY79353.1 - 0.0072 16.6 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain F-box-like PF12937.7 ORY79354.1 - 8.8e-05 22.3 0.2 0.00019 21.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY79354.1 - 0.55 10.2 4.0 23 5.0 0.0 3.2 3 0 0 3 3 3 0 F-box domain Enolase_C PF00113.22 ORY79355.1 - 2.1e-143 476.9 0.2 2.9e-143 476.5 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORY79355.1 - 5.7e-59 198.0 0.0 9.6e-59 197.3 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORY79355.1 - 1.1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORY79355.1 - 0.0029 16.8 0.5 0.0054 15.9 0.2 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Gln-synt_C PF00120.24 ORY79356.1 - 9.5e-88 294.5 0.0 3.1e-87 292.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain DNA_ligase_A_M PF01068.21 ORY79357.1 - 2.6e-35 121.9 3.4 1.5e-26 93.3 0.0 4.5 5 0 0 5 5 5 3 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY79357.1 - 5.5e-31 108.2 0.1 1.2e-30 107.1 0.1 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY79357.1 - 2.5e-21 76.1 0.1 2.2e-20 73.1 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ORY79357.1 - 1.8e-06 28.3 0.0 0.005 17.2 0.0 3.1 3 0 0 3 3 3 2 RNA ligase Trypan_PARP PF05887.11 ORY79357.1 - 4.9 7.1 9.7 16 5.5 9.7 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YabA PF06156.13 ORY79358.1 - 0.21 12.2 2.7 0.43 11.2 2.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA CRAL_TRIO PF00650.20 ORY79359.1 - 1.3e-34 119.3 0.0 1.7e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY79359.1 - 0.078 13.2 0.3 0.17 12.1 0.3 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Y_phosphatase PF00102.27 ORY79360.1 - 1.7e-38 132.5 0.0 1.2e-36 126.4 0.0 2.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY79360.1 - 0.0002 21.5 0.0 0.0016 18.6 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 ORY79360.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioredoxin PF00085.20 ORY79361.1 - 1.7e-27 95.4 0.1 2e-27 95.2 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 ORY79361.1 - 4.5e-05 23.2 0.0 5.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 ORY79361.1 - 5.2e-05 23.2 0.0 5.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 ORY79361.1 - 6e-05 23.4 0.0 0.00054 20.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 ORY79361.1 - 0.0003 20.5 0.1 0.00036 20.3 0.1 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 ORY79361.1 - 0.00088 19.6 0.0 0.0012 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 ORY79361.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 ORY79361.1 - 0.004 16.6 0.0 0.0043 16.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ORY79361.1 - 0.012 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 ORY79361.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin BTB PF00651.31 ORY79362.1 - 0.0065 16.7 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain GFA PF04828.14 ORY79363.1 - 2.3e-13 50.3 0.3 3e-13 49.9 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Sel1 PF08238.12 ORY79364.1 - 1.8e-38 130.1 19.5 3.9e-07 30.5 0.1 7.8 7 0 0 7 7 7 7 Sel1 repeat AA_permease_2 PF13520.6 ORY79365.1 - 6.2e-54 183.4 41.0 7.7e-54 183.1 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY79365.1 - 6.4e-19 67.9 32.7 9.1e-19 67.4 32.7 1.2 1 0 0 1 1 1 1 Amino acid permease SLATT_1 PF18181.1 ORY79365.1 - 2.9 7.9 0.0 2.9 7.9 0.0 4.1 5 0 0 5 5 5 0 SMODS and SLOG-associating 2TM effector domain 1 ADH_N PF08240.12 ORY79366.1 - 1.1e-27 96.1 0.9 2.2e-27 95.1 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY79366.1 - 1.6e-20 73.4 0.2 2.7e-20 72.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY79366.1 - 3.3e-12 46.3 1.8 7.2e-05 22.4 0.6 2.9 1 1 1 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 ORY79366.1 - 2.2e-08 35.2 0.0 5.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY79366.1 - 0.0014 18.0 1.8 0.0029 16.9 1.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ORY79366.1 - 0.0025 17.4 0.5 0.014 14.9 0.2 2.0 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 ORY79366.1 - 0.016 15.4 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 ORY79366.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY79366.1 - 0.082 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding MTS PF05175.14 ORY79366.1 - 0.089 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sacchrp_dh_NADP PF03435.18 ORY79366.1 - 0.095 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY79366.1 - 0.14 12.3 0.4 0.29 11.2 0.4 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-AN1 PF01428.16 ORY79367.1 - 2.1e-10 40.6 10.0 2.8e-10 40.2 10.0 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORY79367.1 - 0.44 10.9 3.7 0.69 10.3 3.7 1.3 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain IPPT PF01715.17 ORY79368.1 - 2.1e-56 191.3 0.0 1.9e-30 106.4 0.0 2.2 2 0 0 2 2 2 2 IPP transferase AAA_16 PF13191.6 ORY79368.1 - 0.0012 19.2 0.6 0.07 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.23 ORY79368.1 - 0.076 13.1 0.1 0.088 12.9 0.1 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 ORY79368.1 - 0.096 12.3 0.3 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY79368.1 - 0.12 13.0 0.1 0.12 13.0 0.1 2.6 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 ORY79368.1 - 0.19 12.0 0.2 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY79368.1 - 5.2 7.2 6.6 4.2 7.5 0.0 3.1 4 0 0 4 4 4 0 AAA domain ERCC4 PF02732.15 ORY79369.1 - 1.1e-05 25.7 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Spore_III_AF PF09581.10 ORY79369.1 - 0.25 11.4 3.6 0.53 10.3 3.6 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Red1 PF07964.11 ORY79369.1 - 0.9 7.7 11.8 1.3 7.1 11.8 1.2 1 0 0 1 1 1 0 Rec10 / Red1 Ribosomal_L27A PF00828.19 ORY79370.1 - 4e-34 118.0 0.0 5.9e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1690 PF07956.11 ORY79371.1 - 1.2e-32 113.2 6.3 1.5e-32 113.0 6.3 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) RR_TM4-6 PF06459.12 ORY79371.1 - 0.02 14.7 2.2 0.024 14.5 2.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2052 PF09747.9 ORY79371.1 - 0.07 13.3 5.7 0.091 12.9 5.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF737 PF05300.11 ORY79371.1 - 0.97 9.8 10.5 0.091 13.1 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Sun2_CC2 PF18580.1 ORY79371.1 - 5.8 7.2 7.5 2.9 8.2 1.1 2.3 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Abhydrolase_1 PF00561.20 ORY79372.1 - 1.4e-35 123.2 0.0 1.7e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY79372.1 - 1.7e-11 45.1 0.5 2.3e-11 44.7 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY79372.1 - 2.1e-11 43.5 0.1 5.7e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 ORY79372.1 - 8.7e-07 29.0 0.0 2.6e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Kelch_3 PF13415.6 ORY79372.1 - 0.1 12.9 0.1 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Galactose oxidase, central domain Nuc_sug_transp PF04142.15 ORY79696.1 - 7.7e-95 317.7 14.7 3.8e-86 289.1 9.9 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 ORY79696.1 - 1.1e-06 28.1 7.1 1.9e-06 27.4 7.1 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY79696.1 - 9.3e-05 22.6 0.5 9.3e-05 22.6 0.5 3.2 3 0 0 3 3 3 1 EamA-like transporter family CRT-like PF08627.10 ORY79696.1 - 0.0025 16.8 0.5 0.0025 16.8 0.5 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 ORY79696.1 - 0.018 14.4 9.6 0.069 12.5 9.6 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF5548 PF17702.1 ORY79696.1 - 0.059 13.1 0.1 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5548) PUNUT PF16913.5 ORY79696.1 - 1 8.5 10.8 4.1 6.5 10.8 1.9 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport ATP-synt_ab PF00006.25 ORY79698.1 - 5.8e-63 212.4 0.0 1.1e-62 211.4 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY79698.1 - 2.9e-21 75.7 1.7 6.1e-21 74.7 1.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 ORY79698.1 - 0.0085 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 ORY79698.1 - 0.0086 15.3 0.6 0.015 14.5 0.1 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 ORY79698.1 - 0.011 16.1 0.0 0.031 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORY79698.1 - 0.011 15.6 0.2 0.029 14.3 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 ORY79698.1 - 0.04 13.3 0.2 0.074 12.4 0.2 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 ORY79698.1 - 0.069 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 ORY79698.1 - 0.14 12.6 0.1 0.58 10.6 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORY79698.1 - 0.16 12.3 3.2 0.35 11.2 0.2 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORY79698.1 - 0.18 12.2 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RraA-like PF03737.15 ORY79699.1 - 1.4e-33 116.2 0.0 1.8e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA PIH1 PF08190.12 ORY79701.1 - 0.022 14.2 0.0 0.082 12.4 0.0 1.9 2 0 0 2 2 2 0 PIH1 N-terminal domain Cyclin_N PF00134.23 ORY79702.1 - 0.0028 17.4 0.0 0.023 14.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_N PF00134.23 ORY79703.1 - 0.026 14.3 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Sec3_C PF09763.9 ORY79704.1 - 4.2e-166 554.3 0.0 5.2e-166 554.0 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 ORY79704.1 - 6.3e-18 64.7 0.0 1.2e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 ORY79704.1 - 5.7e-05 22.0 0.7 0.00011 21.1 0.7 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family FAP206 PF12018.8 ORY79704.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function CCDC-167 PF15188.6 ORY79704.1 - 3.6 8.0 6.3 3.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 IF-2B PF01008.17 ORY79705.1 - 3.3e-57 193.9 0.0 4.2e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.23 ORY79706.1 - 2.1e-12 46.9 0.1 4.1e-12 46.0 0.0 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY79706.1 - 8.6e-10 39.2 0.0 1.8e-09 38.1 0.0 1.5 2 0 0 2 2 2 1 Cyclin CDC45 PF02724.14 ORY79707.1 - 1.6 6.9 10.1 2.1 6.6 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_1 PF00561.20 ORY79708.1 - 2.7e-07 30.5 0.2 5.3e-07 29.5 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY79708.1 - 9.2e-05 21.8 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cyclin_N PF00134.23 ORY79710.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain SH3_9 PF14604.6 ORY79711.1 - 9.7e-05 22.2 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Mit_ribos_Mrp51 PF11709.8 ORY79712.1 - 9.4e-19 68.2 1.4 2e-18 67.2 1.4 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Glyco_trans_1_4 PF13692.6 ORY79713.1 - 0.018 15.5 0.4 0.041 14.3 0.1 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF2681 PF10883.8 ORY79713.1 - 0.32 11.4 0.1 0.32 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Rotamase_2 PF13145.6 ORY79713.1 - 0.38 11.6 12.1 3 8.7 0.7 2.2 2 0 0 2 2 2 0 PPIC-type PPIASE domain Acetyltransf_1 PF00583.25 ORY79714.1 - 1.8e-11 44.3 0.1 2.3e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY79714.1 - 1.5e-07 31.7 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY79714.1 - 6.1e-06 26.1 0.0 9.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY79714.1 - 7.3e-06 25.9 0.0 9.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY79714.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORY79714.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TFIIF_alpha PF05793.12 ORY79715.1 - 5.7 5.4 48.8 10 4.6 48.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Dsh_C PF12316.8 ORY79715.1 - 8.9 6.6 13.1 0.17 12.3 3.0 2.2 1 1 1 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Cwf_Cwc_15 PF04889.12 ORY79716.1 - 0.081 12.6 1.7 0.12 12.1 1.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_A_type_inc PF04508.12 ORY79716.1 - 1.1 9.3 5.2 0.29 11.1 1.4 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Y_phosphatase2 PF03162.13 ORY79717.1 - 2.5e-36 124.8 0.0 5.5e-36 123.6 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family PQ-loop PF04193.14 ORY79718.1 - 4e-21 74.5 17.9 2.7e-11 43.0 2.6 3.5 3 0 0 3 3 3 2 PQ loop repeat DUF1345 PF07077.11 ORY79718.1 - 0.079 12.7 1.8 0.16 11.7 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) DUF4191 PF13829.6 ORY79718.1 - 0.19 11.1 0.5 0.5 9.7 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Frag1 PF10277.9 ORY79719.1 - 1.2e-36 126.4 10.6 1.3e-36 126.2 10.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family GtrA PF04138.14 ORY79719.1 - 8.5e-06 26.0 7.1 8.5e-06 26.0 7.1 1.8 3 0 0 3 3 3 1 GtrA-like protein TauE PF01925.19 ORY79719.1 - 0.0031 17.2 8.3 0.0031 17.2 8.3 1.8 2 0 0 2 2 2 1 Sulfite exporter TauE/SafE SUR7 PF06687.12 ORY79719.1 - 0.079 12.6 4.8 0.22 11.2 4.7 1.9 1 1 0 1 1 1 0 SUR7/PalI family DUF1129 PF06570.11 ORY79719.1 - 0.086 12.3 4.4 0.19 11.2 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF3180 PF11377.8 ORY79719.1 - 0.17 12.0 10.0 0.1 12.8 3.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) VIT1 PF01988.19 ORY79719.1 - 0.2 11.5 1.7 0.3 10.9 1.7 1.3 1 0 0 1 1 1 0 VIT family Cation_ATPase_C PF00689.21 ORY79719.1 - 0.44 10.2 9.2 3.7 7.2 9.2 2.2 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF2085 PF09858.9 ORY79719.1 - 0.51 10.9 7.2 0.24 11.9 2.8 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2085) Abhydrolase_9_N PF15420.6 ORY79719.1 - 1.4 8.9 12.2 4.5 7.2 2.9 2.3 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus F-box-like PF12937.7 ORY79720.1 - 0.0021 17.9 0.7 0.0021 17.9 0.7 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY79720.1 - 0.019 14.9 0.4 0.019 14.9 0.4 2.2 3 0 0 3 3 3 0 F-box domain F-box-like_2 PF13013.6 ORY79720.1 - 0.019 14.9 0.2 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like domain Zn_Tnp_IS1595 PF12760.7 ORY79720.1 - 0.17 11.9 5.4 0.7 9.9 0.2 3.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain PRCC PF10253.9 ORY79720.1 - 0.44 11.3 4.6 0.74 10.6 4.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Nudix_N_2 PF14803.6 ORY79720.1 - 4.1 7.4 6.9 5.7 7.0 0.1 3.1 3 0 0 3 3 3 0 Nudix N-terminal Macoilin PF09726.9 ORY79721.1 - 1.1 7.8 5.4 1.6 7.2 5.4 1.2 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 ORY79721.1 - 9.8 6.0 9.3 9.2 6.1 8.3 1.3 2 0 0 2 2 2 0 SPX domain MFS_1 PF07690.16 ORY79722.1 - 1.2e-15 57.4 14.9 1.2e-15 57.4 14.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY79722.1 - 0.0017 17.3 8.2 0.11 11.3 1.6 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter ECF_trnsprt PF12822.7 ORY79722.1 - 5 7.2 8.5 2.5 8.2 3.3 2.7 2 1 1 3 3 3 0 ECF transporter, substrate-specific component Peptidase_M24 PF00557.24 ORY79725.1 - 5.6e-48 163.4 0.1 8.3e-48 162.9 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORY79725.1 - 5.4e-11 42.6 7.7 5.4e-11 42.6 7.7 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORY79725.1 - 0.068 13.3 5.7 0.21 11.7 5.7 1.8 1 0 0 1 1 1 0 MYND finger Sugar_tr PF00083.24 ORY79726.1 - 2e-89 300.5 19.0 2.3e-89 300.3 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY79726.1 - 7.8e-30 104.0 29.2 7.8e-30 104.0 29.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY79726.1 - 2.9e-05 22.7 1.7 6.2e-05 21.6 1.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 ORY79726.1 - 4.3e-05 22.2 1.0 4.3e-05 22.2 1.0 2.7 2 1 1 3 3 3 1 MFS/sugar transport protein Sugar_tr PF00083.24 ORY79727.1 - 0.00045 19.2 0.2 0.00048 19.1 0.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3593 PF12159.8 ORY79727.1 - 0.069 13.2 0.0 0.09 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Pex14_N PF04695.13 ORY79727.1 - 0.089 13.4 0.4 0.63 10.7 0.1 1.9 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M24 PF00557.24 ORY79728.1 - 1.9e-46 158.4 0.0 2.4e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORY79728.1 - 4.5e-11 42.9 7.4 4.5e-11 42.9 7.4 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORY79728.1 - 0.071 13.2 5.7 0.19 11.9 5.7 1.7 1 0 0 1 1 1 0 MYND finger Zn_clus PF00172.18 ORY79729.1 - 1.7e-05 24.8 7.3 2.9e-05 24.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 ORY79730.1 - 8.9e-33 113.5 16.5 1.4e-32 112.8 16.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY79730.1 - 1.2e-25 90.6 0.0 2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY79730.1 - 9.9e-06 25.6 0.1 0.0067 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY79730.1 - 0.00038 20.9 0.0 0.00076 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ORY79730.1 - 0.00038 20.0 0.1 0.49 9.8 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY79730.1 - 0.00048 20.1 0.1 0.0011 18.9 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 ORY79730.1 - 0.0019 17.8 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY79730.1 - 0.0047 16.6 0.2 0.011 15.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORY79730.1 - 0.024 14.7 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 Dynamin family DUF87 PF01935.17 ORY79730.1 - 0.068 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 ORY79730.1 - 0.12 12.6 0.0 0.72 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 ORY79730.1 - 0.14 11.2 21.2 0.15 11.2 20.2 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Acetyltransf_2 PF00797.17 ORY79731.1 - 3.5e-14 53.2 0.0 3.7e-13 49.8 0.0 2.3 3 0 0 3 3 3 1 N-acetyltransferase HlyIII PF03006.20 ORY79733.1 - 0.18 11.5 7.3 0.24 11.1 0.7 2.1 2 0 0 2 2 2 0 Haemolysin-III related DUF2976 PF11190.8 ORY79733.1 - 8.3 6.3 8.7 3.5 7.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Methyltransf_16 PF10294.9 ORY79734.1 - 1.7e-13 50.6 0.0 2.6e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORY79734.1 - 7.5e-06 25.5 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY79734.1 - 9.1e-06 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 ORY79734.1 - 0.00019 21.2 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 ORY79734.1 - 0.0012 19.5 0.0 0.0021 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TLP1_add_C PF18313.1 ORY79734.1 - 0.0022 17.9 0.2 0.0061 16.5 0.1 1.8 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain Methyltransf_31 PF13847.6 ORY79734.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORY79734.1 - 0.026 15.2 0.0 0.048 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF58 PF01882.18 ORY79734.1 - 0.026 14.8 1.1 0.045 14.0 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function DUF58 HECT_2 PF09814.9 ORY79734.1 - 0.036 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Methyltransf_18 PF12847.7 ORY79734.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2270 PF10028.9 ORY79734.1 - 0.19 11.3 0.2 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2270) Glyco_hydro_43 PF04616.14 ORY79737.1 - 1.2e-63 215.2 0.9 1.6e-63 214.7 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 ORY79737.1 - 3.9e-08 33.3 0.0 9.6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain FAR1 PF03101.15 ORY79738.1 - 0.00014 22.5 11.9 0.042 14.5 0.1 4.5 4 1 0 4 4 4 2 FAR1 DNA-binding domain PBP1_TM PF14812.6 ORY79738.1 - 0.021 15.2 6.2 0.021 15.2 6.2 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 ORY79738.1 - 1.3 8.7 19.6 0.28 10.9 2.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.14 ORY79738.1 - 3.4 7.4 22.4 2.4 7.9 10.2 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 ORY79738.1 - 6.2 6.5 15.3 4.6 6.9 4.3 2.4 2 0 0 2 2 2 0 FAM176 family BTB PF00651.31 ORY79739.1 - 0.013 15.8 0.0 0.043 14.1 0.0 1.8 1 1 1 2 2 2 0 BTB/POZ domain MOZ_SAS PF01853.18 ORY79741.1 - 2.7e-69 232.4 0.1 3.6e-69 232.0 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORY79741.1 - 5.2e-22 77.2 1.9 7e-22 76.8 0.2 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain zf-Sec23_Sec24 PF04810.15 ORY79741.1 - 0.064 13.3 0.1 0.064 13.3 0.1 2.5 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger PH PF00169.29 ORY79742.1 - 0.013 15.9 0.0 0.022 15.3 0.0 1.4 1 0 0 1 1 1 0 PH domain DUF1980 PF09323.10 ORY79742.1 - 0.42 10.5 2.9 12 5.7 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) 2OG-FeII_Oxy PF03171.20 ORY79743.1 - 9e-14 51.8 0.0 1.6e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY79743.1 - 1.4e-13 51.6 0.0 2.7e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DIOX_N PF14226.6 ORY79744.1 - 4.5e-14 53.2 0.0 8.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY79744.1 - 4.6e-14 52.7 0.0 8.1e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ADH_zinc_N PF00107.26 ORY79745.1 - 1.5e-12 47.7 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY79745.1 - 6e-07 29.3 0.0 9.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY79745.1 - 4.8e-06 27.7 0.0 1e-05 26.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 ORY79746.1 - 2.9e-05 24.1 7.8 4.6e-05 23.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_dh PF01070.18 ORY79747.1 - 7.7e-91 304.7 0.0 1.1e-90 304.2 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY79747.1 - 7e-19 67.8 0.0 1.6e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 ORY79747.1 - 0.00024 20.3 0.0 0.00056 19.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY79747.1 - 0.00034 19.7 2.2 0.0038 16.3 0.1 2.7 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ORY79747.1 - 0.00081 18.9 0.3 0.0023 17.4 0.3 1.7 1 1 1 2 2 2 1 Nitronate monooxygenase PA PF02225.22 ORY79747.1 - 0.016 15.2 0.1 3.7 7.6 0.1 2.5 2 0 0 2 2 2 0 PA domain G3P_antiterm PF04309.12 ORY79747.1 - 0.2 11.1 0.9 4.6 6.6 0.0 3.0 4 0 0 4 4 4 0 Glycerol-3-phosphate responsive antiterminator FAR1 PF03101.15 ORY79749.1 - 7.2e-05 23.4 0.2 0.00028 21.5 0.0 2.1 2 0 0 2 2 2 1 FAR1 DNA-binding domain FLYWCH PF04500.16 ORY79749.1 - 0.18 12.0 2.1 0.23 11.6 0.1 2.0 2 0 0 2 2 2 0 FLYWCH zinc finger domain Cyclin_N PF00134.23 ORY79750.1 - 1.7e-10 40.7 0.0 4e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY79750.1 - 7.3e-05 22.7 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORY79750.1 - 0.00046 20.3 0.2 1.1 9.3 0.0 2.9 2 1 0 2 2 2 2 Cyclin, C-terminal domain DUF4936 PF16290.5 ORY79750.1 - 0.12 13.1 0.2 0.3 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) Cyclin_C_2 PF16899.5 ORY79750.1 - 0.18 12.2 0.0 1 9.8 0.0 2.1 2 0 0 2 2 2 0 Cyclin C-terminal domain zf-C2H2 PF00096.26 ORY79751.1 - 7.8e-21 73.3 21.1 0.00011 22.5 1.1 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY79751.1 - 1e-15 57.3 28.2 1.5e-07 31.5 1.1 6.1 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY79751.1 - 3.2e-08 33.7 21.8 0.056 14.3 2.9 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-TRAF PF02176.18 ORY79751.1 - 0.0097 16.6 9.8 0.15 12.8 0.2 3.5 2 1 1 3 3 3 2 TRAF-type zinc finger FOXP-CC PF16159.5 ORY79751.1 - 0.26 11.9 19.5 0.55 10.9 0.2 5.3 3 1 2 5 5 5 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORY79751.1 - 0.27 11.4 4.1 13 5.9 2.7 2.4 2 1 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORY79751.1 - 0.41 10.4 17.1 0.35 10.7 0.3 4.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 ORY79751.1 - 1.1 9.7 4.3 20 5.6 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CGNR PF11706.8 ORY79751.1 - 7.7 6.5 7.3 5.5 6.9 0.4 3.3 3 0 0 3 3 3 0 CGNR zinc finger Peptidase_M50B PF13398.6 ORY79752.1 - 1.1e-20 74.1 16.5 1.1e-20 74.1 16.5 1.5 2 0 0 2 2 2 1 Peptidase M50B-like Ins_P5_2-kin PF06090.12 ORY79753.1 - 2.4e-78 263.9 0.0 2.8e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase FSH1 PF03959.13 ORY79754.1 - 1e-46 159.3 0.0 1.3e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Grg1 PF11034.8 ORY79755.1 - 8e-12 45.2 3.4 1e-11 44.9 3.4 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Zn_clus PF00172.18 ORY79756.1 - 1.5e-07 31.4 14.6 3.1e-07 30.4 14.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 ORY79756.1 - 0.11 12.8 0.3 0.76 10.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain bZIP_1 PF00170.21 ORY79757.1 - 2.1e-07 30.9 6.5 3.1e-07 30.4 6.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY79757.1 - 5.8e-06 26.3 7.8 1.2e-05 25.2 7.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY79757.1 - 0.12 12.9 4.5 0.17 12.4 4.2 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF4820 PF16091.5 ORY79757.1 - 1.4 8.2 3.7 0.48 9.8 0.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Kelch_6 PF13964.6 ORY79760.1 - 1e-10 41.5 0.5 3.2e-06 27.2 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 ORY79760.1 - 1.4e-10 41.0 0.2 3.7e-07 30.1 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY79760.1 - 9.4e-09 34.9 0.2 0.00075 19.4 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 ORY79760.1 - 4.2e-08 33.3 9.9 0.11 12.8 0.0 5.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY79760.1 - 1.6e-07 30.8 0.1 4.3e-05 23.0 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 ORY79760.1 - 1e-06 28.5 2.5 0.012 15.6 0.0 4.2 4 1 0 4 4 4 2 Kelch motif COesterase PF00135.28 ORY79761.1 - 4.4e-83 279.9 0.0 1.7e-82 277.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY79761.1 - 0.0047 16.8 0.8 0.022 14.6 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY79761.1 - 0.041 14.5 0.1 0.064 13.9 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY79761.1 - 0.092 12.4 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold COesterase PF00135.28 ORY79762.1 - 7.9e-60 203.2 0.0 1.2e-59 202.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY79762.1 - 3.3e-07 30.4 0.0 0.0097 15.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY79762.1 - 0.002 17.6 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Aminotran_3 PF00202.21 ORY79763.1 - 7.7e-85 285.0 0.0 8.7e-85 284.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Zn_clus PF00172.18 ORY79764.1 - 0.00044 20.3 9.2 0.00077 19.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY79765.1 - 9.6e-27 93.8 39.6 1.7e-26 93.0 39.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 ORY79767.1 - 4.5e-23 80.4 25.9 5.3e-06 26.6 0.2 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY79767.1 - 3e-22 78.0 20.8 2.6e-07 30.7 0.1 5.3 4 1 1 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY79767.1 - 5.3e-13 48.6 25.0 0.00085 20.0 2.2 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY79767.1 - 2.2e-06 27.8 3.0 0.0056 16.9 0.0 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY79767.1 - 8.6e-05 23.1 7.7 0.043 14.4 0.9 3.7 2 1 2 4 4 4 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY79767.1 - 0.00016 21.9 6.1 0.004 17.4 1.9 2.9 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 ORY79767.1 - 0.0031 17.2 20.6 1.9 8.3 0.1 4.7 5 0 0 5 5 4 4 C2H2-type zinc-finger domain zf-met PF12874.7 ORY79767.1 - 0.0086 16.4 1.0 0.0086 16.4 1.0 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type DUF448 PF04296.13 ORY79767.1 - 0.036 13.9 1.7 3.8 7.4 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF448) zf-C2H2_aberr PF17017.5 ORY79767.1 - 0.05 13.7 7.9 0.6 10.2 0.6 2.3 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 ORY79767.1 - 0.062 13.1 15.0 0.16 11.8 2.3 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORY79767.1 - 0.071 13.0 0.5 0.071 13.0 0.5 4.7 4 3 1 5 5 5 0 zinc-finger of a C2HC-type BolA PF01722.18 ORY79767.1 - 0.087 13.1 0.9 0.087 13.1 0.9 1.7 2 0 0 2 2 2 0 BolA-like protein IBR PF01485.21 ORY79767.1 - 0.19 12.0 11.3 0.54 10.5 6.2 2.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain TRAF6_Z2 PF18048.1 ORY79767.1 - 0.59 10.3 0.2 0.59 10.3 0.2 3.3 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 DUF2256 PF10013.9 ORY79767.1 - 1.1 9.4 0.0 1.1 9.4 0.0 3.9 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) p450 PF00067.22 ORY79768.1 - 4.5e-69 233.4 0.0 5.6e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3168 PF11367.8 ORY79768.1 - 0.07 13.3 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) NAD_binding_6 PF08030.12 ORY79769.1 - 2.8e-19 69.8 0.0 3.9e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY79769.1 - 1.4e-16 60.8 10.8 3e-16 59.7 10.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY79769.1 - 3.3e-11 43.2 0.0 6e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY79769.1 - 0.00091 19.9 0.0 0.065 13.9 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain GMC_oxred_N PF00732.19 ORY79770.1 - 8e-51 173.2 0.0 2.2e-50 171.7 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY79770.1 - 3.9e-29 102.0 2.0 4.8e-29 101.7 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 ORY79770.1 - 0.0042 17.3 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 ORY79770.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AF-4 PF05110.13 ORY79770.1 - 3 5.8 10.9 4.4 5.3 10.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MGTL PF17059.5 ORY79771.1 - 0.044 13.6 0.2 0.044 13.6 0.2 3.1 3 1 0 3 3 3 0 MgtA leader peptide CLASP_N PF12348.8 ORY79772.1 - 4.6e-24 85.2 4.0 9e-07 28.7 0.0 5.6 6 0 0 6 6 6 4 CLASP N terminal HEAT PF02985.22 ORY79772.1 - 2.1e-15 55.5 21.4 0.0011 19.1 0.0 10.3 11 0 0 11 11 11 5 HEAT repeat Cnd1 PF12717.7 ORY79772.1 - 5.3e-13 49.3 0.5 0.035 14.2 0.1 6.9 6 2 1 7 7 7 4 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY79772.1 - 1.8e-10 41.0 21.7 0.0014 19.0 0.1 8.9 7 2 2 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 ORY79772.1 - 1.1e-06 29.0 13.4 0.38 11.3 0.1 8.6 9 0 0 9 9 9 2 HEAT-like repeat RTP1_C1 PF10363.9 ORY79772.1 - 2.5e-05 24.4 0.1 7.7 6.7 0.0 5.1 5 0 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 ORY79772.1 - 0.00026 20.8 0.0 0.046 13.5 0.0 3.7 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 ORY79772.1 - 0.0059 15.2 7.2 3.8 6.0 0.3 5.5 6 1 1 7 7 7 1 Adaptin N terminal region DUF3510 PF12022.8 ORY79772.1 - 0.11 12.8 0.6 1 9.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) Pam17 PF08566.10 ORY79774.1 - 6e-60 201.8 0.0 8e-60 201.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 zf-MYND PF01753.18 ORY79775.1 - 3.1e-07 30.4 12.6 3.1e-07 30.4 12.6 2.1 3 0 0 3 3 3 1 MYND finger Fungal_trans PF04082.18 ORY79776.1 - 1.3e-13 50.6 0.0 2.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ORY79776.1 - 4.3e-07 30.0 10.2 0.00039 20.7 3.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY79776.1 - 4.9e-06 26.7 7.0 0.0053 17.1 0.1 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY79776.1 - 0.0026 18.4 10.0 0.16 12.9 2.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger SAE2 PF08573.10 ORY79776.1 - 0.071 14.2 0.1 0.85 10.8 0.0 2.3 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus zf-C2H2_jaz PF12171.8 ORY79776.1 - 0.35 11.2 5.5 4 7.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.18 ORY79777.1 - 1.3e-14 53.9 0.4 2e-14 53.2 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 ORY79777.1 - 2.1e-11 43.6 2.2 0.00015 22.0 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY79777.1 - 1.1e-06 28.9 5.0 0.03 15.2 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY79777.1 - 3.5e-06 27.2 4.3 0.006 17.0 0.2 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY79777.1 - 0.033 14.5 0.2 0.7 10.2 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY79777.1 - 0.053 13.8 1.0 0.1 12.9 1.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Transket_pyr PF02779.24 ORY79778.1 - 0.027 14.1 0.1 0.032 13.9 0.1 1.1 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Sugar_tr PF00083.24 ORY79779.1 - 2e-99 333.5 29.8 2.9e-99 333.0 29.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY79779.1 - 9.8e-30 103.7 57.0 1.7e-26 93.0 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY79779.1 - 0.00036 19.2 5.4 0.00036 19.2 5.4 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 ORY79779.1 - 0.8 7.9 21.2 0.027 12.8 1.4 3.5 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 ORY79780.1 - 3.1e-08 33.4 0.2 8.5e-08 32.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like Transketolase_N PF00456.21 ORY79781.1 - 9.4e-152 504.7 0.1 1.3e-151 504.3 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY79781.1 - 3.9e-45 153.7 0.0 1.6e-44 151.7 0.0 2.0 3 0 0 3 3 3 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY79781.1 - 1.4e-10 41.1 0.2 6.6e-10 38.9 0.0 2.3 2 1 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY79781.1 - 0.00098 18.4 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DUF5498 PF17602.2 ORY79781.1 - 0.024 15.1 0.3 0.18 12.3 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5498) Terpene_synth PF01397.21 ORY79781.1 - 0.042 13.5 0.1 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain DIOX_N PF14226.6 ORY79782.1 - 8.7e-15 55.5 0.0 1.8e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY79782.1 - 3.3e-09 37.1 0.0 5.7e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Synaphin PF05835.12 ORY79783.1 - 1 9.6 22.0 2.1 8.6 22.0 1.4 1 0 0 1 1 1 0 Synaphin protein PTPRCAP PF15713.5 ORY79783.1 - 1.4 9.2 13.4 3.6 7.9 13.4 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated UCR_14kD PF02271.16 ORY79784.1 - 3.1e-36 123.3 0.2 3.6e-36 123.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit SpoIIE PF07228.12 ORY79785.1 - 1.1e-11 45.0 0.3 5.1e-11 42.8 0.3 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ORY79785.1 - 0.00012 21.8 0.0 0.00032 20.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DIOX_N PF14226.6 ORY79786.1 - 1.9e-20 73.8 0.0 3.2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY79786.1 - 2e-19 70.0 0.0 3.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4248 PF14053.6 ORY79786.1 - 0.18 11.8 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) MFS_1 PF07690.16 ORY79787.1 - 5.2e-23 81.5 32.6 5.2e-23 81.5 32.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.6 ORY79788.1 - 1.8e-14 54.5 0.0 3.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY79788.1 - 2.2e-07 31.3 0.0 4.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_S16 PF00886.19 ORY79788.1 - 0.071 13.2 0.0 0.71 10.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S16 Cys_Met_Meta_PP PF01053.20 ORY79789.1 - 1.2e-127 425.6 0.0 1.4e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY79789.1 - 1.1e-08 34.6 0.1 1.7e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY79789.1 - 2.5e-07 30.3 0.2 4.6e-07 29.5 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORY79789.1 - 4.3e-07 29.2 0.0 8.2e-07 28.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 ORY79789.1 - 0.016 13.7 0.1 0.032 12.8 0.1 1.4 1 0 0 1 1 1 0 Methionine gamma-lyase Beta_elim_lyase PF01212.21 ORY79789.1 - 0.037 13.3 0.0 0.1 11.8 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase GDC-P PF02347.16 ORY79789.1 - 0.039 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein NDK PF00334.19 ORY79790.1 - 4.7e-53 178.8 0.0 5.5e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DPM3 PF08285.11 ORY79791.1 - 0.036 14.3 0.5 0.036 14.3 0.5 3.1 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) ECF_trnsprt PF12822.7 ORY79791.1 - 0.072 13.2 8.7 0.24 11.5 3.8 2.5 1 1 1 2 2 2 0 ECF transporter, substrate-specific component Ly49 PF08391.10 ORY79791.1 - 0.32 11.4 1.3 0.88 10.0 0.0 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region PDR_CDR PF06422.12 ORY79791.1 - 5.6 6.9 6.6 8.2 6.4 1.6 2.9 1 1 1 2 2 2 0 CDR ABC transporter STIMATE PF12400.8 ORY79791.1 - 6.8 7.3 9.4 8.2 7.0 1.3 2.4 2 0 0 2 2 2 0 STIMATE family DUF3671 PF12420.8 ORY79791.1 - 6.9 6.8 7.2 26 4.9 3.9 2.8 2 1 0 2 2 2 0 Protein of unknown function Prok-RING_4 PF14447.6 ORY79794.1 - 0.059 13.2 0.8 0.12 12.3 0.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SP2 PF03014.14 ORY79794.1 - 0.1 11.0 1.2 0.099 11.0 1.2 1.1 1 0 0 1 1 1 0 Structural protein 2 Glyco_hydro_16 PF00722.21 ORY79795.1 - 5.8e-41 139.9 7.5 1.3e-40 138.8 7.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Myco_19_kDa PF05481.12 ORY79795.1 - 0.41 10.9 6.1 0.12 12.7 1.1 2.6 4 0 0 4 4 4 0 Mycobacterium 19 kDa lipoprotein antigen Med3 PF11593.8 ORY79795.1 - 0.82 8.8 10.3 1.2 8.2 10.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RING_2 PF13639.6 ORY79796.1 - 1.5e-06 28.4 5.7 2.5e-06 27.7 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY79796.1 - 0.00036 20.8 4.8 0.0008 19.6 4.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY79796.1 - 0.0034 17.4 1.2 0.0079 16.2 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY79796.1 - 0.026 14.7 4.2 0.06 13.5 4.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY79796.1 - 0.026 14.1 5.2 0.055 13.1 5.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORY79796.1 - 0.15 12.2 5.5 0.31 11.2 5.5 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 ORY79796.1 - 0.15 11.9 5.2 0.3 11.0 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 ORY79796.1 - 0.25 11.3 1.3 0.45 10.4 1.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 ORY79796.1 - 0.52 10.2 3.8 1.1 9.2 3.8 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C3HC4 PF00097.25 ORY79796.1 - 0.86 9.5 5.7 1.5 8.8 5.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY79796.1 - 2.7 8.0 4.5 4.5 7.2 4.5 1.4 1 0 0 1 1 1 0 PHD-finger CENP-B_dimeris PF09026.10 ORY79796.1 - 2.9 8.4 16.4 2.1 8.8 11.4 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-RING-like PF08746.11 ORY79796.1 - 3.5 8.0 6.1 5.7 7.3 6.1 1.4 1 0 0 1 1 1 0 RING-like domain NOA36 PF06524.12 ORY79796.1 - 5.8 6.1 5.6 12 5.1 5.6 1.4 1 0 0 1 1 1 0 NOA36 protein Glyco_transf_15 PF01793.16 ORY79797.1 - 1e-116 389.8 1.8 1.2e-116 389.5 1.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_hydro_98C PF08307.11 ORY79797.1 - 0.0045 16.5 0.1 0.0077 15.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 98 C-terminal domain Striatin PF08232.12 ORY79798.1 - 0.14 12.8 0.1 0.2 12.2 0.1 1.2 1 0 0 1 1 1 0 Striatin family DBD_Tnp_Mut PF03108.15 ORY79799.1 - 0.069 13.2 2.9 0.2 11.7 0.7 2.3 2 0 0 2 2 2 0 MuDR family transposase FAR1 PF03101.15 ORY79802.1 - 1.4e-07 32.1 3.0 0.39 11.4 0.0 3.8 3 0 0 3 3 3 3 FAR1 DNA-binding domain BUD22 PF09073.10 ORY79802.1 - 0.0061 16.0 9.3 0.0061 16.0 9.3 4.1 4 0 0 4 4 4 2 BUD22 DBD_Tnp_Mut PF03108.15 ORY79802.1 - 0.097 12.7 2.5 0.15 12.0 0.5 2.3 2 1 0 2 2 2 0 MuDR family transposase Pet100 PF09803.9 ORY79803.1 - 9.1e-17 61.3 0.1 1.3e-16 60.8 0.1 1.2 1 0 0 1 1 1 1 Pet100 DUF1192 PF06698.11 ORY79803.1 - 0.045 13.8 1.5 0.078 13.0 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3429 PF11911.8 ORY79804.1 - 5.5e-37 127.2 12.4 7.2e-37 126.9 12.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) U79_P34 PF03064.16 ORY79804.1 - 5.4 6.3 9.7 10 5.4 9.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-MYND PF01753.18 ORY79805.1 - 4e-09 36.4 29.1 1.2e-08 34.9 11.4 3.1 3 0 0 3 3 3 2 MYND finger zf-C6H2 PF15801.5 ORY79805.1 - 2.7 8.4 13.2 0.37 11.1 7.1 2.4 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding DUF3379 PF11859.8 ORY80193.1 - 0.1 11.9 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Fig1 PF12351.8 ORY80193.1 - 0.15 11.9 9.0 1 9.2 9.0 1.9 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3377 PF11857.8 ORY80193.1 - 0.44 10.5 2.4 1 9.3 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SHR3_chaperone PF08229.11 ORY80194.1 - 7.5e-23 80.5 1.7 9.4e-23 80.2 1.7 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 COX1 PF00115.20 ORY80194.1 - 0.35 9.7 5.5 0.35 9.7 5.0 1.4 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I AAA PF00004.29 ORY80196.1 - 7e-52 175.3 0.0 5.5e-40 136.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 ORY80196.1 - 5.2e-27 94.1 0.0 1.4e-26 92.7 0.0 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 ORY80196.1 - 7.3e-16 57.7 1.7 2.4e-10 40.0 0.3 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY80196.1 - 2.4e-10 41.0 12.0 1.6e-05 25.3 1.3 5.2 3 1 1 5 5 3 2 AAA ATPase domain AAA_22 PF13401.6 ORY80196.1 - 3e-08 34.0 0.8 0.0027 18.0 0.1 4.0 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.6 ORY80196.1 - 1.5e-06 28.3 0.0 0.081 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORY80196.1 - 8.4e-06 26.0 0.0 0.045 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 ORY80196.1 - 8.6e-06 25.6 0.0 0.0027 17.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 ORY80196.1 - 1e-05 25.5 0.9 0.0099 15.8 0.1 3.4 2 1 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 ORY80196.1 - 2.5e-05 24.2 0.0 0.092 12.5 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 ORY80196.1 - 2.8e-05 24.5 0.0 0.26 11.7 0.0 3.1 3 0 0 3 3 3 2 RNA helicase TsaE PF02367.17 ORY80196.1 - 3.4e-05 23.8 0.0 0.41 10.7 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 ORY80196.1 - 4.3e-05 23.5 0.0 0.55 10.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Rad17 PF03215.15 ORY80196.1 - 4.5e-05 23.5 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain Sigma54_activat PF00158.26 ORY80196.1 - 0.00015 21.5 0.0 0.098 12.4 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 ORY80196.1 - 0.00018 22.0 0.0 0.36 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY80196.1 - 0.00024 20.7 0.1 2.6 7.6 0.0 3.5 2 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 ORY80196.1 - 0.00029 21.4 0.0 0.17 12.4 0.0 3.3 3 0 0 3 3 3 1 ABC transporter DUF815 PF05673.13 ORY80196.1 - 0.00039 19.7 0.0 0.016 14.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 ORY80196.1 - 0.00044 19.6 0.4 0.16 11.2 0.0 2.8 3 0 0 3 3 3 1 TIP49 P-loop domain DUF2075 PF09848.9 ORY80196.1 - 0.0017 17.7 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORY80196.1 - 0.0025 17.4 0.2 0.45 10.0 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY80196.1 - 0.0025 17.1 0.2 1.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 ORY80196.1 - 0.0062 16.2 0.3 0.052 13.3 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 ORY80196.1 - 0.008 16.6 0.0 0.45 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 ORY80196.1 - 0.011 15.6 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein NB-ARC PF00931.22 ORY80196.1 - 0.012 14.8 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 ORY80196.1 - 0.015 15.2 0.1 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.17 ORY80196.1 - 0.022 14.5 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Parvo_NS1 PF01057.17 ORY80196.1 - 0.027 13.6 0.0 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 ORY80196.1 - 0.028 14.5 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORY80196.1 - 0.047 13.4 0.0 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 ORY80196.1 - 0.054 11.4 0.0 0.082 10.8 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_3 PF07726.11 ORY80196.1 - 0.063 13.1 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 ORY80196.1 - 0.066 12.6 0.0 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 ORY80196.1 - 0.071 12.5 1.4 0.87 8.9 0.0 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ORY80196.1 - 0.074 13.3 0.0 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ORY80196.1 - 0.075 12.9 0.1 1 9.2 0.0 2.6 2 1 1 3 3 3 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 ORY80196.1 - 0.077 12.9 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 ORY80196.1 - 0.084 12.8 0.0 8.7 6.2 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Vps4_C PF09336.10 ORY80196.1 - 0.093 12.7 0.3 1.8 8.6 0.1 3.0 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain SKI PF01202.22 ORY80196.1 - 0.14 12.3 0.0 3.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase ATPase PF06745.13 ORY80196.1 - 0.16 11.3 0.0 17 4.7 0.0 2.2 2 0 0 2 2 2 0 KaiC RRM_1 PF00076.22 ORY80197.1 - 0.00064 19.5 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.13 ORY80197.1 - 0.07 13.8 5.8 0.11 13.2 5.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.9 ORY80197.1 - 6.1 5.9 8.9 7.3 5.7 8.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Git3 PF11710.8 ORY80198.1 - 8.5e-11 42.0 4.3 1.4e-10 41.3 4.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ORY80198.1 - 1.3e-08 34.5 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 ORY80198.1 - 0.00043 19.6 0.4 0.00067 19.0 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 ORY80198.1 - 0.018 15.1 0.2 0.049 13.7 0.2 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term Glutaredoxin PF00462.24 ORY80199.1 - 6.9e-13 48.6 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 ORY80199.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 ORY80199.1 - 0.019 15.3 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 ORY80199.1 - 0.022 14.5 0.0 0.12 12.1 0.0 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 ORY80199.1 - 0.036 14.5 0.0 0.048 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1223 PF06764.11 ORY80199.1 - 0.14 12.2 0.2 7.6 6.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1223) ATP_transf PF09830.9 ORY80200.1 - 8.3e-21 73.9 0.0 1.5e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 ORY80200.1 - 0.007 16.1 0.1 3.2 7.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4922) HIT PF01230.23 ORY80200.1 - 0.013 16.3 0.0 0.031 15.0 0.0 1.6 1 0 0 1 1 1 0 HIT domain bZIP_2 PF07716.15 ORY80201.1 - 3.3e-08 33.5 21.7 6.3e-07 29.4 12.3 2.5 2 1 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORY80201.1 - 1.9e-06 27.9 17.7 5.3e-06 26.4 9.8 2.5 2 1 0 2 2 2 2 bZIP transcription factor Mto2_bdg PF12808.7 ORY80201.1 - 0.0029 17.8 13.5 0.011 16.1 0.3 3.3 2 1 1 3 3 3 2 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF2630 PF10944.8 ORY80201.1 - 0.037 14.5 0.2 0.037 14.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) DUF724 PF05266.14 ORY80201.1 - 0.1 12.4 2.9 0.15 11.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BBP1_C PF15272.6 ORY80201.1 - 0.16 11.8 3.8 0.27 11.0 3.8 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TSC22 PF01166.18 ORY80201.1 - 0.18 12.1 1.7 0.33 11.3 0.6 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 ORY80201.1 - 0.23 12.0 14.5 0.13 12.8 8.4 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor ADIP PF11559.8 ORY80201.1 - 0.23 11.5 11.2 2.8 8.0 5.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 ORY80201.1 - 0.27 11.4 14.3 0.12 12.5 1.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PLA2_B PF01735.18 ORY80202.1 - 3.7e-117 391.7 0.4 4.5e-117 391.5 0.4 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Epimerase PF01370.21 ORY80203.1 - 4.5e-07 29.6 0.0 2.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY80203.1 - 1.5e-05 25.5 0.1 0.00018 21.9 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 ORY80203.1 - 0.00019 21.1 0.1 0.00028 20.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family DXP_reductoisom PF02670.16 ORY80203.1 - 0.043 14.5 0.0 0.078 13.7 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase IU_nuc_hydro PF01156.19 ORY80204.1 - 8.1e-82 275.2 0.0 9.6e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FH2 PF02181.23 ORY80205.1 - 6.3e-85 285.5 0.3 3.9e-84 282.9 0.0 2.4 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 ORY80205.1 - 1.1e-29 103.3 0.6 1.4e-26 93.2 0.7 2.7 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 ORY80205.1 - 2e-21 76.5 0.2 5.3e-21 75.1 0.2 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Tup_N PF08581.10 ORY80205.1 - 0.0055 17.0 2.0 1.1 9.6 0.0 3.2 2 0 0 2 2 2 1 Tup N-terminal DUF812 PF05667.11 ORY80205.1 - 0.12 11.2 12.9 0.23 10.3 12.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SlyX PF04102.12 ORY80205.1 - 0.28 11.8 11.1 11 6.7 0.0 6.5 4 1 0 5 5 5 0 SlyX HAUS-augmin3 PF14932.6 ORY80205.1 - 0.54 9.8 14.6 2.1 7.8 5.4 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FAM184 PF15665.5 ORY80205.1 - 0.67 9.7 10.8 0.34 10.7 0.2 2.6 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DASH_Spc34 PF08657.10 ORY80205.1 - 0.85 9.4 10.4 0.095 12.5 1.5 2.6 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF2203 PF09969.9 ORY80205.1 - 0.99 10.1 11.3 1.6 9.4 3.3 4.3 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 ORY80205.1 - 1.2 8.5 12.2 38 3.5 12.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 ORY80205.1 - 2.1 8.7 10.8 7.7 6.9 1.5 3.6 4 0 0 4 4 3 0 TSC-22/dip/bun family CCDC106 PF15794.5 ORY80205.1 - 7.4 6.2 13.3 1.5 8.5 8.9 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 GAS PF13851.6 ORY80205.1 - 9.9 5.5 21.4 0.098 12.0 7.4 3.1 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding ABC2_membrane PF01061.24 ORY80206.1 - 3.3e-62 209.6 52.2 9.2e-33 113.4 24.3 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY80206.1 - 6.1e-30 104.5 0.0 3.9e-18 66.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY80206.1 - 6.3e-22 77.3 1.6 4.2e-18 65.0 0.0 3.2 3 0 0 3 3 3 2 CDR ABC transporter RsgA_GTPase PF03193.16 ORY80206.1 - 4.5e-06 26.7 0.0 9.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 ORY80206.1 - 0.00079 19.1 0.0 0.0059 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY80206.1 - 0.00084 19.8 0.1 0.0029 18.0 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORY80206.1 - 0.0016 18.3 0.0 3.9 7.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 ORY80206.1 - 0.0029 17.9 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORY80206.1 - 0.011 15.8 0.3 0.042 13.9 0.3 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY80206.1 - 0.013 15.3 0.1 0.046 13.5 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORY80206.1 - 0.12 12.4 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Dynamin family ABC2_membrane_3 PF12698.7 ORY80206.1 - 0.99 8.4 47.8 0.031 13.4 12.9 3.7 3 1 0 3 3 3 0 ABC-2 family transporter protein RNA_ligase PF09414.10 ORY80207.1 - 1.1e-23 84.3 0.0 2.5e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 ORY80207.1 - 3.5e-09 37.0 0.1 0.0004 20.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain PTPlike_phytase PF14566.6 ORY80207.1 - 0.00017 21.8 0.3 0.00034 20.8 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.20 ORY80207.1 - 0.00031 20.6 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain KTI12 PF08433.10 ORY80207.1 - 0.00078 19.0 0.0 0.41 10.1 0.1 2.2 2 0 0 2 2 2 2 Chromatin associated protein KTI12 Y_phosphatase3 PF13350.6 ORY80207.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY80207.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Flavi_M PF01004.19 ORY80207.1 - 0.2 11.5 0.2 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M AIM3 PF17096.5 ORY80208.1 - 0.39 11.7 4.1 0.31 12.0 0.4 2.3 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 F-box PF00646.33 ORY80210.1 - 2.2e-06 27.4 0.2 6.3e-06 25.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY80210.1 - 1.7e-05 24.6 0.2 4.2e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like DUF3246 PF11596.8 ORY80210.1 - 0.34 10.3 14.5 2.2 7.6 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) RRN3 PF05327.11 ORY80210.1 - 1.2 7.6 14.7 1.5 7.2 0.6 2.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ETRAMP PF09716.10 ORY80210.1 - 5.2 7.2 5.2 3.8 7.6 2.2 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Vps52 PF04129.12 ORY80211.1 - 3.6e-55 187.7 0.0 3e-41 141.7 0.0 2.1 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 ORY80211.1 - 0.00012 20.6 0.0 0.0064 14.9 0.0 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 ERCC3_RAD25_C PF16203.5 ORY80212.1 - 6.8e-124 412.0 0.4 1.7e-123 410.7 0.4 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 ORY80212.1 - 3.5e-37 127.4 0.0 7.7e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY80212.1 - 3.1e-16 59.8 0.0 6e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY80212.1 - 2.9e-11 43.7 0.2 7.3e-11 42.4 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ORY80212.1 - 1.5e-09 37.1 0.0 2.1e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 ORY80212.1 - 0.0011 18.8 0.1 0.0019 18.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 ORY80212.1 - 0.043 13.2 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Rrn6 PF10214.9 ORY80214.1 - 0.015 13.9 3.7 0.02 13.4 3.7 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor ArAE_2_N PF10337.9 ORY80215.1 - 0.0026 16.9 12.6 0.0056 15.8 0.1 2.9 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 ORY80215.1 - 0.014 15.2 1.1 0.078 12.8 0.1 2.3 2 1 0 2 2 2 0 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY80215.1 - 1.2 9.3 38.3 0.052 13.7 15.6 2.9 2 1 0 2 2 2 0 Fusaric acid resistance protein-like ECH_1 PF00378.20 ORY80216.1 - 3.2e-26 92.2 0.1 1e-20 74.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY80216.1 - 2.4e-15 56.9 0.5 5.5e-14 52.4 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase GIT_SHD PF08518.11 ORY80217.1 - 5e-24 83.6 11.9 1.7e-12 46.7 3.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 ORY80217.1 - 0.00029 20.9 0.1 0.00029 20.9 0.1 2.9 3 0 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term HeLo PF14479.6 ORY80217.1 - 0.013 15.4 1.3 0.013 15.4 1.3 3.1 3 1 1 4 4 4 0 Prion-inhibition and propagation Cache_3-Cache_2 PF17201.4 ORY80217.1 - 0.11 11.8 0.2 0.29 10.4 0.2 1.6 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain GAS PF13851.6 ORY80217.1 - 0.8 9.0 20.7 0.036 13.4 9.4 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 ORY80217.1 - 1.5 8.9 25.2 0.036 14.1 3.6 3.6 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein SHE3 PF17078.5 ORY80217.1 - 2.6 7.7 16.4 0.89 9.2 6.6 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 TFIIF_alpha PF05793.12 ORY80218.1 - 0.0014 17.3 3.0 0.0014 17.3 3.0 3.0 2 1 1 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) G-patch PF01585.23 ORY80218.1 - 0.0071 16.2 0.0 0.026 14.4 0.0 2.0 1 0 0 1 1 1 1 G-patch domain RNA_polI_A34 PF08208.11 ORY80218.1 - 0.012 15.7 4.7 0.012 15.7 4.7 3.3 2 1 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC27 PF09507.10 ORY80218.1 - 6.2 6.1 53.9 3.3 7.0 9.1 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 F-box PF00646.33 ORY80219.1 - 3.3e-06 26.8 0.2 9e-06 25.4 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY80219.1 - 0.00013 21.7 2.1 0.00026 20.8 0.3 2.3 2 0 0 2 2 2 1 F-box-like FancD2 PF14631.6 ORY80219.1 - 0.46 7.8 2.9 0.68 7.2 2.9 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SIR4_SID PF16991.5 ORY80219.1 - 1.4 8.9 9.8 1.6 8.8 3.7 2.6 2 0 0 2 2 2 0 Sir4 SID domain Asp PF00026.23 ORY80220.1 - 1.8e-61 208.3 9.2 2.2e-61 208.0 9.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY80220.1 - 1.8e-11 44.6 4.3 0.00011 22.5 0.5 3.1 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY80220.1 - 0.0024 18.5 2.5 0.14 12.8 0.3 3.2 2 1 0 2 2 2 1 Aspartyl protease MAGI_u1 PF16663.5 ORY80221.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.6 3 0 0 3 3 3 0 Unstructured region on MAGI DNA_pol_B PF00136.21 ORY80222.1 - 1.1e-93 314.4 0.0 1.6e-93 313.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY80222.1 - 1e-20 74.1 0.0 8.4e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY80222.1 - 1.1e-11 45.0 5.1 2.3e-11 44.0 5.1 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta TRAPPC-Trs85 PF12739.7 ORY80223.1 - 1.8e-89 300.6 0.0 2.3e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Sec39 PF08314.11 ORY80224.1 - 4.4e-12 45.3 0.0 1.6e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Sec39 PF08314.11 ORY80225.1 - 7.5e-49 166.9 0.0 9.5e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 F-box PF00646.33 ORY80226.1 - 2.7e-06 27.1 0.3 6.5e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY80226.1 - 4.6e-05 23.2 0.4 4.6e-05 23.2 0.4 2.1 2 0 0 2 2 2 1 F-box-like FancD2 PF14631.6 ORY80226.1 - 0.059 10.8 2.7 0.098 10.1 2.7 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PIN_4 PF13638.6 ORY80227.1 - 2.2e-23 83.0 0.0 3.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 PIN domain Diphthamide_syn PF01866.17 ORY80228.1 - 2.1e-92 309.8 0.0 1.4e-52 179.0 0.0 3.8 2 1 0 2 2 2 2 Putative diphthamide synthesis protein F-box-like PF12937.7 ORY80229.1 - 2.2e-05 24.2 0.5 6.9e-05 22.7 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY80229.1 - 0.0073 16.2 0.3 0.0073 16.2 0.3 2.9 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.7 ORY80229.1 - 0.56 10.7 8.3 0.5 10.9 1.7 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Senescence PF06911.12 ORY80230.1 - 2.1e-44 152.0 8.6 3.3e-44 151.4 8.6 1.3 1 0 0 1 1 1 1 Senescence-associated protein Phageshock_PspD PF09584.10 ORY80231.1 - 0.063 13.3 1.4 0.14 12.2 1.4 1.6 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) DUF2070 PF09843.9 ORY80231.1 - 3.1 6.0 7.7 4.3 5.5 7.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF805 PF05656.14 ORY80231.1 - 5.4 7.5 10.8 0.52 10.7 4.9 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF805) polyprenyl_synt PF00348.17 ORY80232.1 - 1.6e-62 210.9 0.0 1.9e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Evr1_Alr PF04777.13 ORY80233.1 - 7.6e-26 90.5 0.1 1.4e-25 89.6 0.1 1.4 1 0 0 1 1 1 1 Erv1 / Alr family T6SS_HCP PF05638.12 ORY80233.1 - 5.4e-06 26.8 0.1 1e-05 26.0 0.1 1.4 1 0 0 1 1 1 1 Type VI secretion system effector, Hcp SNAD4 PF18750.1 ORY80233.1 - 0.019 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 ORY80233.1 - 0.03 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 APOBEC1 APOBEC4 PF18775.1 ORY80233.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 APOBEC4 PMT_4TMC PF16192.5 ORY80234.1 - 0.75 9.3 9.0 0.42 10.2 1.5 2.5 2 1 0 2 2 2 0 C-terminal four TMM region of protein-O-mannosyltransferase Phageshock_PspD PF09584.10 ORY80235.1 - 0.0088 16.0 0.2 0.023 14.7 0.2 1.6 1 0 0 1 1 1 1 Phage shock protein PspD (Phageshock_PspD) Amidase PF01425.21 ORY80236.1 - 8.6e-124 413.9 0.2 1e-123 413.6 0.2 1.0 1 0 0 1 1 1 1 Amidase hDGE_amylase PF14701.6 ORY80237.1 - 8.7e-172 572.1 0.0 1.1e-171 571.8 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 ORY80237.1 - 4.1e-118 394.7 0.0 5.5e-118 394.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 ORY80237.1 - 8.5e-75 251.7 0.0 1.4e-74 251.0 0.0 1.3 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 ORY80237.1 - 1.6e-20 73.0 0.0 3.2e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 ORY80237.1 - 0.16 11.5 0.1 0.44 10.1 0.0 1.7 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Zn_clus PF00172.18 ORY80238.1 - 9e-06 25.7 12.7 1.9e-05 24.7 12.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain E1_dh PF00676.20 ORY80239.1 - 1.4e-86 290.2 0.0 1.7e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Aa_trans PF01490.18 ORY80240.1 - 1.8e-31 109.3 24.8 2.1e-31 109.1 24.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 7TM_GPCR_Srsx PF10320.9 ORY80240.1 - 0.23 10.8 8.3 0.046 13.1 0.5 2.8 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx F-box-like PF12937.7 ORY80242.1 - 0.00055 19.8 0.2 0.00055 19.8 0.2 2.4 3 0 0 3 3 3 1 F-box-like Suc_Fer-like PF06999.12 ORY80243.1 - 4e-46 157.4 0.0 1.8e-45 155.3 0.0 1.8 1 1 0 1 1 1 1 Sucrase/ferredoxin-like SOBP PF15279.6 ORY80244.1 - 1.6 9.2 13.5 2.6 8.6 13.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein KAR9 PF08580.10 ORY80244.1 - 8.7 4.7 22.2 13 4.1 22.2 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Serglycin PF04360.12 ORY80245.1 - 0.058 13.3 3.4 0.14 12.1 3.4 1.6 1 0 0 1 1 1 0 Serglycin Glypican PF01153.19 ORY80245.1 - 0.74 8.6 4.9 1 8.1 4.9 1.1 1 0 0 1 1 1 0 Glypican FAM196 PF15265.6 ORY80245.1 - 1.5 8.2 10.4 2 7.8 10.4 1.1 1 0 0 1 1 1 0 FAM196 family DUF4769 PF15992.5 ORY80245.1 - 3.7 7.3 3.9 5.6 6.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) p450 PF00067.22 ORY80246.1 - 9e-74 248.9 0.0 1e-73 248.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Steroid_dh PF02544.16 ORY80247.1 - 1.3e-21 77.1 0.1 1.1e-06 28.7 0.1 3.3 3 0 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ORY80247.1 - 0.00013 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF4499 PF14934.6 ORY80247.1 - 0.064 13.6 0.8 0.15 12.4 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Tma16 PF11176.8 ORY80248.1 - 1e-33 116.2 1.8 1.4e-33 115.9 1.8 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 MEA1 PF06910.11 ORY80248.1 - 0.0041 17.7 0.0 0.01 16.5 0.0 1.5 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) AIP3 PF03915.13 ORY80249.1 - 2e-115 386.2 0.0 3.9e-115 385.2 0.0 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 ORY80249.1 - 0.17 11.7 2.3 0.67 9.7 2.3 2.1 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain GNVR PF13807.6 ORY80249.1 - 0.45 10.5 2.8 0.48 10.4 0.5 2.2 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase KASH_CCD PF14662.6 ORY80249.1 - 1.9 8.3 9.8 2.2 8.1 2.7 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH zf-PARP PF00645.18 ORY80250.1 - 2.6e-09 37.8 0.0 6.8e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region K_trans PF02705.16 ORY80251.1 - 2.1e-159 531.5 17.4 2.6e-159 531.2 17.4 1.1 1 0 0 1 1 1 1 K+ potassium transporter 5-FTHF_cyc-lig PF01812.20 ORY80253.1 - 9.1e-32 110.4 0.0 2.3e-31 109.1 0.0 1.6 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Phage_connect_1 PF05135.13 ORY80253.1 - 0.17 12.4 0.0 0.47 11.0 0.0 1.7 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein MmgE_PrpD PF03972.14 ORY80255.1 - 7.3e-155 515.8 0.3 9.8e-155 515.4 0.3 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Pro_CA PF00484.19 ORY80256.1 - 1.7e-39 135.6 1.4 2.6e-39 135.0 1.4 1.3 1 0 0 1 1 1 1 Carbonic anhydrase RhoGAP PF00620.27 ORY80257.1 - 1.7e-11 44.2 0.0 4.9e-11 42.7 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ORY80257.1 - 0.074 13.3 0.1 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain zf-PARP PF00645.18 ORY80258.1 - 4.3e-19 69.2 0.0 8.7e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 ORY80258.1 - 6.8 6.9 10.8 0.096 12.6 3.0 2.3 2 0 0 2 2 2 0 AT hook motif Sec1 PF00995.23 ORY80259.1 - 1e-127 427.8 0.0 1.4e-127 427.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family CNH PF00780.22 ORY80260.1 - 3.5e-78 263.0 0.0 6.5e-78 262.1 0.0 1.4 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 ORY80260.1 - 5.1e-42 143.2 0.0 8.5e-42 142.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 ORY80260.1 - 4.6e-34 118.2 0.0 7.5e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 ORY80260.1 - 7.7e-13 48.3 0.0 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 ORY80260.1 - 0.00053 19.8 0.2 0.0069 16.2 0.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.6 ORY80260.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_16 PF17838.1 ORY80260.1 - 0.15 11.9 0.2 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 PH domain Acyl-CoA_dh_1 PF00441.24 ORY80261.1 - 3.1e-43 147.6 3.1 8.8e-43 146.1 3.5 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY80261.1 - 1.4e-28 99.8 0.0 4.1e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY80261.1 - 3.6e-24 84.8 0.0 8.3e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY80261.1 - 5.1e-15 55.9 4.4 8.5e-15 55.2 4.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY80261.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.6 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Prefoldin PF02996.17 ORY80262.1 - 3.3e-28 98.0 3.2 4.7e-28 97.5 3.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 ORY80262.1 - 0.00056 19.8 8.1 0.0016 18.4 0.5 2.4 2 1 0 2 2 2 1 Prefoldin subunit SOAR PF16533.5 ORY80262.1 - 0.0045 16.9 0.9 0.068 13.2 0.1 2.1 2 0 0 2 2 2 1 STIM1 Orai1-activating region AIP3 PF03915.13 ORY80262.1 - 0.0083 15.3 2.3 0.0098 15.0 2.3 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 DUF4407 PF14362.6 ORY80262.1 - 0.059 12.7 2.2 0.21 10.9 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cep57_MT_bd PF06657.13 ORY80262.1 - 0.072 13.6 3.8 0.62 10.6 0.4 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 GIT_CC PF16559.5 ORY80262.1 - 0.087 12.7 1.0 0.087 12.7 1.0 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 ORY80262.1 - 0.096 12.7 1.7 1.7 8.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1192 PF06698.11 ORY80262.1 - 0.13 12.3 1.3 0.75 9.9 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Phage_GP20 PF06810.11 ORY80262.1 - 0.14 12.0 5.4 1.8 8.4 0.3 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.8 ORY80262.1 - 0.15 12.3 7.1 3.2 8.0 1.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Uso1_p115_C PF04871.13 ORY80262.1 - 0.16 12.4 7.4 0.43 10.9 0.7 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4763 PF15960.5 ORY80262.1 - 0.19 11.0 5.4 0.9 8.8 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Tup_N PF08581.10 ORY80262.1 - 0.34 11.2 7.6 5.6 7.3 1.3 3.2 3 1 1 4 4 4 0 Tup N-terminal Spc7 PF08317.11 ORY80262.1 - 0.74 8.6 8.5 1.2 8.0 1.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein EamA PF00892.20 ORY80263.1 - 6.2e-23 81.5 25.3 1.1e-11 45.0 7.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ORY80263.1 - 0.027 13.8 4.2 0.088 12.1 0.4 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family RseC_MucC PF04246.12 ORY80263.1 - 2.1 8.3 11.1 7 6.6 2.0 3.6 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Fis1_TPR_C PF14853.6 ORY80264.1 - 4.2e-24 84.4 0.6 5.7e-24 83.9 0.6 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ORY80264.1 - 9.5e-06 25.2 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 ORY80264.1 - 0.00018 21.4 0.4 0.00029 20.7 0.4 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY80264.1 - 0.015 15.1 0.6 0.025 14.4 0.6 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY80264.1 - 0.047 13.7 0.1 0.093 12.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY80264.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-met2 PF12907.7 ORY80265.1 - 1.1e-06 28.6 0.8 1.6e-06 28.1 0.8 1.3 1 0 0 1 1 1 1 Zinc-binding zf-C3HC PF07967.13 ORY80265.1 - 0.064 13.3 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like WD40 PF00400.32 ORY80266.1 - 1.1e-14 54.5 0.2 8.7e-06 26.4 0.1 5.8 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY80266.1 - 1.7e-05 25.0 0.1 0.1 12.9 0.1 3.9 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PPL5 PF18168.1 ORY80266.1 - 0.0034 16.7 0.2 0.0053 16.1 0.2 1.2 1 0 0 1 1 1 1 Prim-pol family 5 Cytochrom_D1 PF02239.16 ORY80266.1 - 0.0048 15.5 0.0 0.028 13.0 0.0 2.2 4 0 0 4 4 4 1 Cytochrome D1 heme domain Nup160 PF11715.8 ORY80266.1 - 0.012 14.3 0.0 0.58 8.7 0.0 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 DUF1604 PF07713.13 ORY80267.1 - 1.2e-36 124.4 2.1 1.2e-36 124.4 2.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 ORY80267.1 - 2.5e-06 27.3 0.2 2.5e-06 27.3 0.2 2.5 2 0 0 2 2 2 1 G-patch domain Med19 PF10278.9 ORY80267.1 - 0.025 14.5 2.1 0.048 13.6 2.1 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 G-patch_2 PF12656.7 ORY80267.1 - 0.076 13.1 2.4 0.13 12.4 0.4 2.5 2 0 0 2 2 2 0 G-patch domain Noggin PF05806.12 ORY80267.1 - 0.2 11.6 0.2 0.54 10.2 0.3 1.6 2 0 0 2 2 2 0 Noggin Vac7 PF12751.7 ORY80267.1 - 2 7.7 13.7 0.35 10.3 4.4 2.2 1 1 0 2 2 2 0 Vacuolar segregation subunit 7 Ribosomal_L33 PF00471.20 ORY80268.1 - 9.1e-06 26.0 0.0 9.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 zf-PARP PF00645.18 ORY80269.1 - 2e-18 67.0 0.0 4e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region AT_hook PF02178.19 ORY80269.1 - 0.0086 15.8 4.4 0.037 13.9 4.4 2.2 1 0 0 1 1 1 1 AT hook motif CSD PF00313.22 ORY80270.1 - 2.8e-19 68.7 0.1 4.3e-19 68.1 0.1 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain PX PF00787.24 ORY80271.1 - 5.9e-20 71.4 0.9 1.1e-19 70.4 0.2 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 ORY80271.1 - 9.2e-06 25.4 0.6 0.01 15.4 0.0 2.3 2 0 0 2 2 2 2 Vps5 C terminal like Sec15 PF04091.12 ORY80272.1 - 9e-98 327.6 0.8 1.7e-97 326.6 0.8 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 ORY80272.1 - 0.0028 17.6 1.8 0.01 15.7 0.2 2.5 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain RINT1_TIP1 PF04437.13 ORY80272.1 - 0.0033 16.4 2.3 0.0033 16.4 2.3 2.5 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Rac1 PF09632.10 ORY80272.1 - 0.024 13.8 0.2 0.059 12.5 0.2 1.6 1 0 0 1 1 1 0 Rac1-binding domain COG5 PF10392.9 ORY80272.1 - 0.033 14.4 0.1 0.033 14.4 0.1 3.1 3 1 0 3 3 3 0 Golgi transport complex subunit 5 U3snoRNP10 PF12397.8 ORY80272.1 - 0.085 13.2 1.0 0.49 10.8 0.1 2.7 3 0 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Vps51 PF08700.11 ORY80272.1 - 0.12 12.5 2.4 0.16 12.1 0.1 2.6 3 0 0 3 3 3 0 Vps51/Vps67 RGP PF03214.13 ORY80272.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide COG2 PF06148.11 ORY80272.1 - 0.83 9.7 8.7 0.46 10.6 1.4 3.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA PF00004.29 ORY80274.1 - 2e-06 28.3 0.0 2.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY80274.1 - 0.00093 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY80274.1 - 0.0019 18.6 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY80274.1 - 0.0033 18.0 0.0 0.0033 18.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY80274.1 - 0.0049 16.1 0.0 0.0049 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 ORY80274.1 - 0.0075 16.2 0.0 0.0075 16.2 0.0 1.1 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 ORY80274.1 - 0.013 15.3 0.0 0.014 15.1 0.0 1.2 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 ORY80274.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 ORY80274.1 - 0.018 14.8 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY80274.1 - 0.023 13.8 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 ORY80274.1 - 0.024 14.9 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 ORY80274.1 - 0.026 14.3 0.0 0.04 13.6 0.0 1.3 1 1 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 ORY80274.1 - 0.033 14.4 0.0 0.033 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY80274.1 - 0.037 13.3 0.0 0.043 13.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 ORY80274.1 - 0.042 13.5 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 ORY80274.1 - 0.044 13.9 0.1 0.054 13.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY80274.1 - 0.049 13.1 0.0 0.063 12.8 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 ORY80274.1 - 0.05 13.5 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 NTPase SKI PF01202.22 ORY80274.1 - 0.055 13.6 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase TIP49 PF06068.13 ORY80274.1 - 0.058 12.6 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 ORY80274.1 - 0.063 13.2 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 ORY80274.1 - 0.072 12.8 0.3 0.13 12.0 0.1 1.6 1 1 1 2 2 2 0 P-loop containing region of AAA domain dNK PF01712.19 ORY80274.1 - 0.084 12.7 0.0 0.084 12.7 0.0 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase RNA_helicase PF00910.22 ORY80274.1 - 0.094 13.1 0.0 0.094 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ORY80274.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA12 PF10443.9 ORY80274.1 - 0.27 9.9 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein Dimer_Tnp_hAT PF05699.14 ORY80277.1 - 0.00033 20.4 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4295 PF14128.6 ORY80277.1 - 0.16 11.8 0.1 0.46 10.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) TBPIP PF07106.13 ORY80278.1 - 7.4e-17 61.0 0.1 8.1e-17 60.9 0.1 1.0 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain TrmB PF01978.19 ORY80278.1 - 0.1 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB V-SNARE_C PF12352.8 ORY80279.1 - 0.043 14.1 5.2 0.12 12.7 0.3 3.0 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Atg14 PF10186.9 ORY80279.1 - 1.6 7.8 11.6 2.4 7.2 11.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 ORY80279.1 - 1.8 6.4 9.6 2.3 6.0 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ANAPC5 PF12862.7 ORY80279.1 - 2 8.6 3.8 7.4 6.7 0.3 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 WD40 PF00400.32 ORY80280.1 - 2.3e-44 148.5 15.2 5.1e-08 33.4 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 ORY80280.1 - 8.7e-10 38.3 2.9 2.7e-09 36.8 2.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY80280.1 - 1.8e-07 30.9 3.7 4e-07 29.7 3.7 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORY80280.1 - 3.2e-07 30.6 0.7 0.0011 19.2 0.0 4.3 1 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY80280.1 - 9.9e-05 22.0 2.2 0.11 12.1 0.2 2.6 1 1 1 2 2 2 2 PQQ-like domain WD40_like PF17005.5 ORY80280.1 - 0.00041 19.8 0.0 0.056 12.8 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 ORY80280.1 - 0.0017 17.1 2.2 1.7 7.2 0.0 3.9 4 0 0 4 4 4 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ORY80280.1 - 0.048 12.6 0.5 14 4.5 0.0 3.0 2 1 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain EHN PF06441.12 ORY80281.1 - 1.7e-32 112.0 0.2 4.1e-32 110.8 0.2 1.7 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY80281.1 - 3.1e-18 66.4 0.0 5.7e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY80281.1 - 0.0048 17.5 4.7 0.018 15.6 4.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L4 PF00573.22 ORY80282.1 - 6.7e-50 169.4 0.0 8.8e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family His_Phos_1 PF00300.22 ORY80284.1 - 1.6e-39 135.6 0.0 2.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 ORY80284.1 - 0.037 13.4 0.2 0.049 13.0 0.0 1.4 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Cwf_Cwc_15 PF04889.12 ORY80285.1 - 3.4e-52 177.6 32.0 4e-52 177.4 32.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 ORY80285.1 - 0.0043 16.5 28.8 0.0047 16.4 28.8 1.2 1 0 0 1 1 1 1 SDA1 DNA_pol_phi PF04931.13 ORY80285.1 - 0.18 9.9 40.9 0.22 9.6 40.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 ORY80285.1 - 0.39 10.1 21.5 0.58 9.5 21.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 ORY80285.1 - 1.2 7.4 25.5 1.5 7.0 25.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 ORY80285.1 - 1.9 7.8 29.7 2.4 7.4 29.7 1.2 1 0 0 1 1 1 0 BUD22 MFAP1 PF06991.11 ORY80285.1 - 2.1 8.2 34.8 1.3 8.8 22.5 2.1 1 1 1 2 2 2 0 Microfibril-associated/Pre-mRNA processing EMP24_GP25L PF01105.24 ORY80285.1 - 3.3 7.6 7.7 5.4 6.9 7.7 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TFIIF_alpha PF05793.12 ORY80285.1 - 4.3 5.8 34.3 5.7 5.4 34.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Drc1-Sld2 PF11719.8 ORY80285.1 - 7.4 6.0 20.1 10 5.5 20.1 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Nop14 PF04147.12 ORY80285.1 - 7.9 4.6 34.3 9.6 4.3 34.3 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.6 ORY80286.1 - 3.9e-08 33.9 0.2 2.2e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ORY80286.1 - 0.0054 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY80286.1 - 0.008 15.8 0.0 0.034 13.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA12 PF10443.9 ORY80286.1 - 0.0086 14.9 0.2 0.94 8.1 0.0 3.3 3 1 1 4 4 4 1 RNA12 protein RsgA_GTPase PF03193.16 ORY80286.1 - 0.011 15.6 0.0 0.095 12.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 ORY80286.1 - 0.027 14.9 0.2 0.15 12.5 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORY80286.1 - 0.054 12.6 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORY80286.1 - 0.078 13.3 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 ORY80286.1 - 0.17 11.2 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region E1-E2_ATPase PF00122.20 ORY80287.1 - 3.9e-46 156.9 0.1 3.9e-46 156.9 0.1 2.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY80287.1 - 3.8e-38 131.0 0.3 8.1e-38 130.0 0.3 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY80287.1 - 1.7e-20 74.2 7.9 1.2e-19 71.4 6.3 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY80287.1 - 8.8e-15 54.2 0.1 4.6e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY80287.1 - 3.4e-08 33.5 0.0 9.7e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY80287.1 - 2e-06 27.8 1.7 0.0012 18.6 0.6 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY80287.1 - 0.0031 17.9 0.0 0.0075 16.7 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4923 PF16270.5 ORY80287.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) Hydrolase_6 PF13344.6 ORY80287.1 - 0.11 12.7 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2127 PF09900.9 ORY80287.1 - 0.41 10.9 7.7 0.09 13.0 2.1 2.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2127) Abhydrolase_1 PF00561.20 ORY80288.1 - 1.2e-22 80.8 0.1 1.3e-22 80.7 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY80288.1 - 2.4e-17 64.3 2.7 5.2e-17 63.2 2.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY80288.1 - 1.7e-11 43.9 0.0 7.1e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY80288.1 - 0.045 13.5 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AF-4 PF05110.13 ORY80289.1 - 0.12 10.5 30.9 0.11 10.6 30.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 ORY80289.1 - 0.9 8.0 17.5 1 7.9 17.5 1.1 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 ORY80289.1 - 1.2 9.0 35.0 0.31 10.9 31.7 1.6 2 0 0 2 2 2 0 SPX domain Glyoxalase PF00903.25 ORY80290.1 - 6.7e-10 39.2 0.0 8.1e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ORY80290.1 - 0.0044 16.9 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase-like domain NUFIP1 PF10453.9 ORY80290.1 - 0.04 13.8 0.1 0.065 13.1 0.1 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RhoGAP PF00620.27 ORY80292.1 - 3.5e-24 85.4 0.0 7.1e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Fez1 PF06818.15 ORY80292.1 - 0.00024 21.6 15.2 0.00064 20.2 15.2 1.7 1 0 0 1 1 1 1 Fez1 T7SS_ESX_EspC PF10824.8 ORY80292.1 - 0.074 13.5 2.1 0.23 12.0 1.1 2.3 1 1 1 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm YPEB PF14620.6 ORY80292.1 - 0.86 8.9 5.6 1.6 8.0 5.6 1.5 1 0 0 1 1 1 0 YpeB sporulation DUF4094 PF13334.6 ORY80292.1 - 8.5 6.9 9.1 17 5.9 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SUV3_C PF12513.8 ORY80293.1 - 9.2e-17 60.7 0.1 1.9e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 ORY80293.1 - 4.2e-14 52.1 0.0 1.6e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 ORY80293.1 - 1.5e-12 47.9 0.0 3.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY80293.1 - 0.017 14.9 0.0 0.13 12.0 0.0 2.4 2 1 0 2 2 2 0 DEAD/DEAH box helicase Peptidase_M48 PF01435.18 ORY80294.1 - 2.5e-30 105.7 0.0 7.1e-30 104.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M48 ADH_zinc_N PF00107.26 ORY80295.1 - 0.00042 20.3 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Reovirus_L2 PF06016.11 ORY80296.1 - 1.3 6.1 2.4 1.5 5.9 2.4 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) RINGv PF12906.7 ORY80297.1 - 4.3e-13 49.1 4.8 7.3e-13 48.4 4.8 1.4 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.29 ORY80297.1 - 0.51 10.3 4.7 0.87 9.5 4.7 1.4 1 0 0 1 1 1 0 PHD-finger Abhydrolase_9_N PF15420.6 ORY80297.1 - 1.3 8.9 6.9 12 5.8 3.7 2.8 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Pcc1 PF09341.10 ORY80300.1 - 9.7e-21 73.7 0.6 1.2e-20 73.4 0.6 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 TRADD_N PF09034.10 ORY80300.1 - 0.024 14.7 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 TRADD, N-terminal domain NUDIX PF00293.28 ORY80302.1 - 4.4e-15 55.9 0.0 1e-14 54.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 ORY80302.1 - 4e-11 43.5 0.0 1.1e-10 42.1 0.0 1.8 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 ORY80302.1 - 0.043 13.5 0.8 0.083 12.6 0.8 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Fungal_trans_2 PF11951.8 ORY80656.1 - 2.3e-15 56.3 0.2 4.4e-15 55.4 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY80656.1 - 7.7e-05 22.7 7.7 0.00014 21.9 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY80657.1 - 1.1e-20 73.8 0.0 7.1e-20 71.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY80657.1 - 2.7e-05 24.2 10.5 4.7e-05 23.4 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4919 PF16266.5 ORY80657.1 - 0.0084 16.1 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4919) Fungal_trans_2 PF11951.8 ORY80658.1 - 3.9e-12 45.7 0.0 8.3e-12 44.6 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY80658.1 - 0.00089 19.3 8.6 0.0016 18.5 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRRCT PF01463.24 ORY80658.1 - 6.9 7.5 7.5 24 5.8 0.9 4.2 4 0 0 4 4 4 0 Leucine rich repeat C-terminal domain Fungal_trans_2 PF11951.8 ORY80659.1 - 5.2e-17 61.7 0.1 8.3e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY80659.1 - 0.0015 18.6 4.8 0.0015 18.6 4.8 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4287 PF14117.6 ORY80659.1 - 0.086 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Mito_carr PF00153.27 ORY80660.1 - 1e-53 179.2 4.7 1.2e-17 63.6 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pilus_CpaD PF09476.10 ORY80660.1 - 0.0041 16.9 0.0 1.4 8.6 0.0 2.8 3 0 0 3 3 3 2 Pilus biogenesis CpaD protein (pilus_cpaD) MFS_1 PF07690.16 ORY80661.1 - 5.2e-24 84.8 39.8 2e-12 46.8 17.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY80661.1 - 2.9e-05 23.1 0.1 2.9e-05 23.1 0.1 3.2 3 1 0 4 4 4 2 Sugar (and other) transporter Mobilization_B PF17511.2 ORY80661.1 - 0.24 11.8 4.1 2.6 8.4 0.8 2.4 2 0 0 2 2 2 0 Mobilization protein B EF-hand_1 PF00036.32 ORY80662.1 - 3.1e-28 95.2 15.0 6.7e-08 31.6 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY80662.1 - 5.9e-23 81.1 6.0 6.3e-13 49.0 1.5 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY80662.1 - 1.6e-21 74.3 9.4 1.1e-05 25.0 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORY80662.1 - 1.6e-19 68.5 14.8 2e-06 27.0 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY80662.1 - 6e-12 45.2 13.9 5.7e-05 22.9 1.4 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY80662.1 - 9.4e-07 29.2 0.1 0.025 14.9 0.1 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY80662.1 - 5e-05 23.2 7.3 0.01 15.8 0.9 3.8 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY80662.1 - 0.00013 22.3 0.1 0.17 12.3 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain DUF1191 PF06697.12 ORY80662.1 - 0.22 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Dockerin_1 PF00404.18 ORY80662.1 - 0.4 10.9 6.0 2.3 8.5 2.4 3.2 2 2 1 3 3 3 0 Dockerin type I domain Sua5_yciO_yrdC PF01300.18 ORY80663.1 - 5.9e-47 159.5 0.0 1.1e-46 158.6 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ORY80663.1 - 9.2e-28 97.5 0.0 1.4e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding F-box-like PF12937.7 ORY80664.1 - 1.9e-08 34.1 0.1 4.1e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY80664.1 - 0.0025 17.6 6.1 0.0055 16.6 2.9 2.6 2 1 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY80664.1 - 0.14 12.0 0.1 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 F-box CTNNBL PF08216.11 ORY80665.1 - 1e-27 96.3 0.0 2.3e-27 95.2 0.0 1.6 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear MOR2-PAG1_C PF14225.6 ORY80665.1 - 0.12 12.2 0.3 6.3 6.6 0.0 3.0 2 1 0 2 2 2 0 Cell morphogenesis C-terminal Arm_3 PF16186.5 ORY80665.1 - 0.59 9.7 0.0 0.59 9.7 0.0 2.4 2 0 0 2 2 2 0 Atypical Arm repeat TBCC PF07986.12 ORY80668.1 - 3.2e-25 88.2 0.1 6.2e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C HSF_DNA-bind PF00447.17 ORY80672.1 - 1.2e-29 102.7 0.0 2.1e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding CENP-H PF05837.12 ORY80672.1 - 3.4 8.1 5.9 16 6.0 1.0 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) MWFE PF15879.5 ORY80673.1 - 8.1e-23 80.3 0.0 1e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DUF1088 PF06469.11 ORY80673.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Tom7 PF08038.12 ORY80674.1 - 2.5e-17 62.2 0.3 2.8e-17 62.1 0.3 1.0 1 0 0 1 1 1 1 TOM7 family NIF PF03031.18 ORY80675.1 - 2.3e-41 141.1 0.0 3.4e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EcsC PF12787.7 ORY80675.1 - 0.34 10.6 1.5 0.55 9.9 1.5 1.3 1 0 0 1 1 1 0 EcsC protein family FAP PF07174.11 ORY80675.1 - 0.96 8.8 28.5 0.85 9.0 25.8 2.0 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) DUF5310 PF17237.2 ORY80676.1 - 1.3e-16 60.2 2.5 2.4e-16 59.3 0.0 2.4 2 0 0 2 2 2 1 Family of unknown function (DUF5310) DUF3409 PF11889.8 ORY80676.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) UPF0029 PF01205.19 ORY80678.1 - 4.6e-33 113.7 0.0 7e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 ORY80678.1 - 7.6e-06 26.2 0.3 2.9e-05 24.3 0.3 2.0 1 1 0 1 1 1 1 RWD domain p31comet PF06581.12 ORY80679.1 - 0.064 12.4 0.1 0.08 12.1 0.1 1.1 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding RRP7 PF12923.7 ORY80681.1 - 4.7e-11 42.9 0.9 5.9e-09 36.1 1.6 2.6 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 ORY80681.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 ORY80681.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 ORY80681.1 - 0.2 11.5 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ald_Xan_dh_C2 PF02738.18 ORY80682.1 - 6.5e-193 642.1 0.3 9e-193 641.7 0.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 ORY80682.1 - 8.7e-40 136.2 0.0 1.7e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 ORY80682.1 - 1.9e-32 111.9 0.3 3.7e-32 110.9 0.3 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.17 ORY80682.1 - 4.6e-30 103.8 0.0 2e-29 101.8 0.0 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 ORY80682.1 - 5e-25 87.3 0.0 1.1e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 ORY80682.1 - 3.7e-07 30.0 0.2 1.5e-06 28.1 0.2 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MOSC_N PF03476.16 ORY80683.1 - 3.3e-27 94.7 0.0 6.1e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 ORY80683.1 - 6.7e-23 81.2 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 ORY80683.1 - 5.2e-18 65.1 0.0 8.4e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Med17 PF10156.9 ORY80684.1 - 7.5e-06 24.9 5.1 0.00044 19.1 1.7 3.3 2 2 0 2 2 2 2 Subunit 17 of Mediator complex AAA PF00004.29 ORY80686.1 - 3.5e-92 305.7 0.0 2.5e-46 157.4 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY80686.1 - 9e-23 79.8 2.9 1.2e-13 50.7 1.6 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORY80686.1 - 2.9e-14 53.1 0.0 4.7e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY80686.1 - 1.3e-12 48.4 1.6 0.00011 22.7 0.0 4.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 ORY80686.1 - 4.2e-12 46.2 0.6 6.6e-05 22.9 0.2 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY80686.1 - 2.8e-10 40.6 0.6 0.0073 16.6 0.0 4.2 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.14 ORY80686.1 - 4.6e-10 39.9 0.0 0.00035 20.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY80686.1 - 8.7e-10 38.9 0.0 0.00027 21.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 ORY80686.1 - 1.9e-09 37.2 0.3 5.5e-05 22.5 0.1 2.8 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_14 PF13173.6 ORY80686.1 - 2.6e-07 30.7 0.0 0.033 14.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ORY80686.1 - 3.1e-07 30.0 0.5 0.01 15.2 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ORY80686.1 - 1.4e-06 28.2 0.1 0.06 13.1 0.1 2.5 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 ORY80686.1 - 1.8e-06 28.3 0.0 0.038 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORY80686.1 - 2.8e-06 27.7 0.0 0.087 13.2 0.0 2.8 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.12 ORY80686.1 - 6.4e-06 26.2 0.8 0.055 13.4 0.1 3.4 4 0 0 4 4 4 2 NACHT domain ABC_tran PF00005.27 ORY80686.1 - 1e-05 26.1 0.1 0.17 12.4 0.1 2.8 2 1 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 ORY80686.1 - 1.4e-05 24.5 0.1 0.12 11.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 ORY80686.1 - 1.6e-05 25.5 0.0 0.29 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY80686.1 - 2.2e-05 24.2 2.3 0.24 11.0 0.1 4.1 3 1 1 4 4 4 1 AAA domain AAA_17 PF13207.6 ORY80686.1 - 2.4e-05 24.8 0.5 0.097 13.1 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 ORY80686.1 - 3.3e-05 23.5 0.0 0.24 10.9 0.0 2.8 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 ORY80686.1 - 3.6e-05 23.6 0.0 0.085 12.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY80686.1 - 5.2e-05 23.3 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain TsaE PF02367.17 ORY80686.1 - 5.2e-05 23.2 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 ORY80686.1 - 6.9e-05 23.0 0.0 0.019 15.1 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family ATPase PF06745.13 ORY80686.1 - 0.00016 21.1 0.6 2.4 7.4 0.1 3.2 2 1 0 3 3 3 1 KaiC Sigma54_activat PF00158.26 ORY80686.1 - 0.00033 20.4 0.1 0.38 10.4 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain Vps4_C PF09336.10 ORY80686.1 - 0.00038 20.4 0.2 0.088 12.8 0.1 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Sigma54_activ_2 PF14532.6 ORY80686.1 - 0.00038 20.6 0.0 0.96 9.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 ORY80686.1 - 0.00094 18.4 0.0 0.021 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 ORY80686.1 - 0.0023 17.2 0.0 1.1 8.4 0.0 2.6 3 0 0 3 3 2 1 NB-ARC domain AAA_24 PF13479.6 ORY80686.1 - 0.0029 17.4 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 ORY80686.1 - 0.0032 16.6 0.1 1.9 7.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 ORY80686.1 - 0.0035 16.8 0.2 2.5 7.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein TniB PF05621.11 ORY80686.1 - 0.008 15.6 0.0 11 5.3 0.0 3.5 3 0 0 3 3 3 0 Bacterial TniB protein SKI PF01202.22 ORY80686.1 - 0.008 16.3 0.0 6 7.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase ATPase_2 PF01637.18 ORY80686.1 - 0.012 15.6 0.0 2.1 8.2 0.0 3.0 2 2 1 4 4 3 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 ORY80686.1 - 0.013 15.2 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 ORY80686.1 - 0.015 15.0 0.0 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_11 PF13086.6 ORY80686.1 - 0.02 14.7 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORY80686.1 - 0.029 14.3 0.1 7.1 6.5 0.0 2.6 2 1 0 2 2 2 0 NTPase AFG1_ATPase PF03969.16 ORY80686.1 - 0.039 12.9 0.0 5.4 5.8 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_19 PF13245.6 ORY80686.1 - 0.098 13.0 2.1 23 5.3 1.0 3.1 2 1 0 2 2 2 0 AAA domain IPT PF01745.16 ORY80686.1 - 0.12 11.7 0.1 7.9 5.8 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase SRPRB PF09439.10 ORY80686.1 - 0.14 11.6 0.0 14 5.1 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MCM PF00493.23 ORY80686.1 - 0.15 11.2 0.0 7.1 5.7 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain Erv26 PF04148.13 ORY80687.1 - 7.2e-60 202.3 0.9 9.1e-60 202.0 0.9 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.8 ORY80687.1 - 0.018 14.9 2.1 0.049 13.6 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Thaumatin PF00314.17 ORY80688.1 - 0.0011 18.7 10.0 0.0083 15.8 8.1 2.8 1 1 0 1 1 1 1 Thaumatin family Zip PF02535.22 ORY80689.1 - 1.3e-40 139.6 16.1 4.3e-40 137.9 16.1 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Yippee-Mis18 PF03226.14 ORY80692.1 - 1.8e-14 53.8 0.0 2.1e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Snf7 PF03357.21 ORY80693.1 - 3e-09 36.7 14.0 3e-09 36.7 14.0 1.5 1 1 1 2 2 2 1 Snf7 DMSP_lyase PF16867.5 ORY80693.1 - 0.0029 17.3 0.3 0.0081 15.8 0.0 1.8 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase SYCE1 PF15233.6 ORY80693.1 - 0.25 11.4 7.7 0.025 14.6 3.2 1.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 Ribosomal_L1 PF00687.21 ORY80694.1 - 1.4e-47 162.1 1.0 1.7e-47 161.8 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TPR_9 PF13371.6 ORY80695.1 - 3.8e-17 62.2 17.8 7.8e-05 22.7 1.1 6.1 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORY80695.1 - 1.5e-11 43.6 0.4 0.0014 18.4 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY80695.1 - 2.7e-10 39.5 10.3 0.011 15.7 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY80695.1 - 5.1e-07 29.4 0.0 0.15 12.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY80695.1 - 5.2e-07 29.2 0.0 1.1 9.5 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY80695.1 - 0.0003 20.4 0.0 0.24 11.1 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 ORY80695.1 - 0.028 15.2 13.1 27 6.0 0.1 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY80695.1 - 0.13 12.8 0.9 19 5.8 0.1 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY80695.1 - 0.16 11.9 4.1 5.9 6.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY80695.1 - 0.6 10.4 7.8 3.7 7.9 0.2 4.1 3 3 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY80695.1 - 1.2 9.9 14.4 1.7 9.4 0.9 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat Pheromone PF08015.11 ORY80695.1 - 1.8 9.6 10.7 8.3 7.5 10.7 2.2 1 1 0 1 1 1 0 Fungal mating-type pheromone UAA PF08449.11 ORY80696.1 - 3.2e-43 148.1 13.6 1.6e-42 145.7 13.6 1.8 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 ORY80696.1 - 0.012 14.8 4.2 0.22 10.7 0.7 2.3 2 0 0 2 2 2 0 Nucleotide-sugar transporter EamA PF00892.20 ORY80696.1 - 2.4 8.4 32.1 0.25 11.5 15.6 4.0 3 2 0 3 3 3 0 EamA-like transporter family MnmE_helical PF12631.7 ORY80699.1 - 1.1e-45 156.3 0.9 1.8e-45 155.7 0.9 1.3 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 ORY80699.1 - 1.1e-30 106.3 0.0 7.8e-30 103.6 0.0 2.2 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 ORY80699.1 - 5.3e-18 65.2 0.0 1.1e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY80699.1 - 2.9e-06 26.9 0.0 5.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY80699.1 - 6.4e-06 26.3 0.0 0.00017 21.7 0.0 2.4 1 1 1 2 2 2 1 Dynamin family AAA_28 PF13521.6 ORY80699.1 - 0.037 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY80699.1 - 0.07 13.0 0.1 1.2 9.0 0.0 2.7 1 1 1 2 2 2 0 RsgA GTPase MCM PF00493.23 ORY80699.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 ORY80699.1 - 0.17 12.4 0.0 0.38 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Arf PF00025.21 ORY80699.1 - 0.17 11.3 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Pro_isomerase PF00160.21 ORY80700.1 - 1.4e-19 70.9 0.0 1.9e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GTP_EFTU PF00009.27 ORY80701.1 - 3.2e-54 183.5 0.0 5.4e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORY80701.1 - 2.5e-16 59.5 0.0 7.4e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ORY80701.1 - 1.1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 ORY80701.1 - 3.6e-05 23.5 0.0 0.00021 21.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 ORY80701.1 - 8.1e-05 22.9 0.0 0.00028 21.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY80701.1 - 0.00032 20.7 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Aa_trans PF01490.18 ORY80702.1 - 4.3e-09 35.6 1.0 4.6e-09 35.5 1.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FHIPEP PF00771.20 ORY80702.1 - 0.056 11.9 0.1 0.065 11.7 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family Aa_trans PF01490.18 ORY80703.1 - 7.7e-25 87.4 30.1 1.7e-24 86.3 30.1 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SLATT_5 PF18160.1 ORY80703.1 - 7.7 5.8 5.1 3.4 7.0 0.4 2.4 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 F-box-like PF12937.7 ORY80704.1 - 4.5e-05 23.3 0.1 0.00014 21.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY80704.1 - 0.26 11.2 8.0 0.081 12.8 2.5 2.8 2 1 0 2 2 2 0 F-box domain LRR_4 PF12799.7 ORY80704.1 - 9.1 6.9 10.4 45 4.6 0.2 5.1 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) SWIB PF02201.18 ORY80705.1 - 2e-25 88.5 0.0 3.9e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 ORY80705.1 - 5e-11 42.4 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 DEK C terminal domain DUF4481 PF14800.6 ORY80705.1 - 0.032 13.7 0.2 0.047 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Pro_isomerase PF00160.21 ORY80707.1 - 3.6e-47 160.6 0.0 4e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Prefoldin_2 PF01920.20 ORY80711.1 - 1.8e-21 76.1 2.3 2.2e-21 75.8 2.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Cep57_MT_bd PF06657.13 ORY80711.1 - 0.0059 17.0 0.9 0.78 10.2 0.1 2.3 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Prefoldin PF02996.17 ORY80711.1 - 0.0059 16.5 1.8 0.061 13.2 1.4 2.1 1 1 0 1 1 1 1 Prefoldin subunit RXLR PF16810.5 ORY80711.1 - 0.078 13.4 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Fer4 PF00037.27 ORY80712.1 - 5.6e-14 51.3 17.5 1.8e-08 33.8 4.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ORY80712.1 - 3.8e-13 49.8 10.5 5.9e-13 49.2 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ORY80712.1 - 2.5e-10 41.1 8.2 2.4e-05 25.2 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 ORY80712.1 - 1.8e-09 37.6 6.5 0.00024 21.1 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY80712.1 - 2.4e-09 37.1 21.6 9.2e-07 28.9 12.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORY80712.1 - 9.8e-09 35.5 3.1 0.00019 21.8 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ORY80712.1 - 1.6e-08 34.6 10.6 2.8e-08 33.8 10.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ORY80712.1 - 4.3e-07 29.7 17.8 0.00041 20.3 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 ORY80712.1 - 6.7e-07 29.0 11.6 0.0028 17.6 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ORY80712.1 - 6.3e-06 26.3 11.0 0.00031 21.0 1.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 ORY80712.1 - 0.00014 22.4 11.1 0.031 14.8 12.0 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 ORY80712.1 - 0.00088 19.8 10.8 0.12 13.0 0.5 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 ORY80712.1 - 0.0029 17.8 5.4 0.23 11.7 0.4 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 ORY80712.1 - 0.019 15.1 8.4 0.55 10.5 1.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 ORY80712.1 - 0.23 12.5 16.3 0.36 11.9 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 ORY80712.1 - 0.27 12.1 11.7 2.1 9.2 1.7 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain ETF_QO PF05187.13 ORY80712.1 - 0.28 11.3 6.3 1.8 8.8 0.8 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Nucleoporin_FG PF13634.6 ORY80713.1 - 3.3e-14 53.5 43.0 2e-08 34.9 16.9 2.7 1 1 1 2 2 2 2 Nucleoporin FG repeat region Fe-ADH PF00465.19 ORY80714.1 - 1.4e-86 290.6 0.0 1.8e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORY80714.1 - 1.5e-12 47.8 0.0 1.2e-09 38.3 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase PPR_2 PF13041.6 ORY80715.1 - 1e-19 70.4 0.0 1.4e-11 44.4 0.0 5.0 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.6 ORY80715.1 - 8.9e-07 28.9 0.0 0.0055 16.8 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 ORY80715.1 - 3.2e-05 23.9 0.1 0.0054 16.9 0.1 3.7 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 ORY80715.1 - 9e-05 21.9 0.1 0.4 10.0 0.0 3.5 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP F-box-like PF12937.7 ORY80716.1 - 2.4e-06 27.3 3.7 5.8e-06 26.1 3.7 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORY80716.1 - 0.026 14.4 0.9 0.089 12.7 0.9 1.9 1 1 0 1 1 1 0 F-box domain STIMATE PF12400.8 ORY80717.1 - 3.2e-33 114.9 5.4 4.5e-33 114.4 5.4 1.2 1 0 0 1 1 1 1 STIMATE family AAA PF00004.29 ORY80718.1 - 1.6e-51 174.2 0.0 1.6e-38 132.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 ORY80718.1 - 9.3e-10 38.1 0.2 8.5e-08 31.9 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 ORY80718.1 - 2.6e-09 37.5 0.0 0.0004 20.7 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY80718.1 - 7.1e-09 36.3 0.1 0.0013 19.2 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 ORY80718.1 - 1.1e-08 35.4 0.0 3.7e-06 27.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 ORY80718.1 - 2.7e-08 33.5 0.0 7.3e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY80718.1 - 3.5e-08 33.4 0.1 0.0055 16.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY80718.1 - 4.4e-08 33.2 0.1 0.0027 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORY80718.1 - 1.1e-07 31.4 0.7 0.0044 16.3 0.2 2.7 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_33 PF13671.6 ORY80718.1 - 1.4e-06 28.6 0.0 0.047 13.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 ORY80718.1 - 6.4e-06 26.0 0.0 0.047 13.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY80718.1 - 8.3e-06 25.3 5.2 0.0074 15.7 0.1 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY80718.1 - 1.2e-05 25.6 0.0 0.21 12.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 ORY80718.1 - 2e-05 25.1 0.0 0.045 14.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain PhoH PF02562.16 ORY80718.1 - 3e-05 23.6 0.0 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.6 ORY80718.1 - 3.5e-05 23.6 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY80718.1 - 3.9e-05 23.6 1.0 0.051 13.5 0.0 3.5 4 0 0 4 4 3 1 NACHT domain Sigma54_activat PF00158.26 ORY80718.1 - 5.2e-05 23.0 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 ORY80718.1 - 5.3e-05 23.8 1.7 0.27 11.8 0.1 3.3 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 ORY80718.1 - 0.00018 21.5 0.0 0.3 11.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 ORY80718.1 - 0.00025 20.5 0.3 0.015 14.7 0.2 2.3 2 0 0 2 2 2 1 KaiC AAA_7 PF12775.7 ORY80718.1 - 0.00031 20.3 1.0 0.041 13.4 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 ORY80718.1 - 0.00052 20.4 0.1 0.98 9.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 ORY80718.1 - 0.00064 19.6 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORY80718.1 - 0.00075 19.8 0.0 0.94 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY80718.1 - 0.0014 18.4 1.7 0.48 10.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 ORY80718.1 - 0.0015 18.6 0.0 0.55 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY80718.1 - 0.0022 17.2 0.1 0.62 9.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 ORY80718.1 - 0.0024 17.5 0.6 2.5 7.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 ORY80718.1 - 0.0035 17.2 0.0 0.53 10.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORY80718.1 - 0.0054 17.2 0.1 1.2 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ORY80718.1 - 0.0056 16.6 0.1 15 5.4 0.0 3.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 ORY80718.1 - 0.0057 15.8 0.0 3.3 6.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.15 ORY80718.1 - 0.015 15.3 0.0 2 8.4 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit KTI12 PF08433.10 ORY80718.1 - 0.025 14.0 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 ORY80718.1 - 0.039 13.2 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AFG1_ATPase PF03969.16 ORY80718.1 - 0.041 12.8 0.0 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase DUF2075 PF09848.9 ORY80718.1 - 0.056 12.7 0.4 8.1 5.6 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 ORY80718.1 - 0.087 11.9 0.0 8.6 5.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Hydin_ADK PF17213.3 ORY80718.1 - 0.09 13.0 0.1 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain NTPase_1 PF03266.15 ORY80718.1 - 0.099 12.5 0.0 18 5.2 0.0 2.8 2 0 0 2 2 2 0 NTPase Rad17 PF03215.15 ORY80718.1 - 0.12 12.3 0.1 13 5.6 0.0 2.7 3 0 0 3 3 2 0 Rad17 P-loop domain TniB PF05621.11 ORY80718.1 - 0.14 11.5 0.1 24 4.3 0.1 3.0 2 1 0 2 2 2 0 Bacterial TniB protein DAP3 PF10236.9 ORY80718.1 - 0.19 10.9 0.1 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 ORY80718.1 - 0.19 11.5 1.6 10 6.0 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain Vps5 PF09325.10 ORY80719.1 - 4.6e-19 68.9 4.9 7e-19 68.3 4.9 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORY80719.1 - 2e-09 37.4 0.0 4.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 PX domain COG2 PF06148.11 ORY80719.1 - 0.18 11.9 5.4 8 6.6 0.7 3.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 CtnDOT_TraJ PF07863.11 ORY80719.1 - 4.3 8.1 5.1 48 4.7 0.4 3.1 3 0 0 3 3 3 0 Homologues of TraJ from Bacteroides conjugative transposon FUSC PF04632.12 ORY80719.1 - 8.4 4.8 9.4 4.8 5.6 7.4 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Nup54 PF13874.6 ORY80719.1 - 9.7 6.3 10.4 6.7 6.8 6.2 2.6 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 2-Hacid_dh_C PF02826.19 ORY80722.1 - 3.1e-36 124.4 0.4 1.3e-22 80.0 0.0 3.2 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY80722.1 - 0.033 14.8 0.5 0.073 13.7 0.5 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORY80722.1 - 0.068 13.2 0.1 18 5.4 0.1 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Isochorismatase PF00857.20 ORY80723.1 - 5.6e-23 82.0 0.0 9e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family SAP18 PF06487.12 ORY80724.1 - 6.6e-28 97.6 0.0 8.7e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Cornichon PF03311.14 ORY80725.1 - 3.8e-51 172.5 13.9 4.3e-51 172.3 13.9 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2189 PF09955.9 ORY80725.1 - 0.068 13.4 0.2 0.068 13.4 0.2 2.2 1 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Lipase_3 PF01764.25 ORY80726.1 - 1.3e-11 44.5 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PCI PF01399.27 ORY80727.1 - 2.5e-11 44.0 0.0 5.6e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 ORY80727.1 - 7.7e-08 31.9 0.7 7.7e-08 31.9 0.7 2.1 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix DUF885 PF05960.11 ORY80727.1 - 0.0024 17.6 0.7 0.012 15.3 0.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF885) JAB PF01398.21 ORY80728.1 - 1.6e-16 60.4 0.0 2.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ORY80728.1 - 7e-16 58.6 0.2 1.2e-15 57.9 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function He_PIG PF05345.12 ORY80729.1 - 1.2e-13 50.9 25.1 0.0002 21.5 4.9 5.9 5 0 0 5 5 5 5 Putative Ig domain Mid2 PF04478.12 ORY80729.1 - 0.054 13.3 0.0 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Na_H_Exchanger PF00999.21 ORY80730.1 - 1e-48 166.0 47.1 1.5e-48 165.5 47.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Iso_dh PF00180.20 ORY80731.1 - 1.8e-80 270.7 0.0 2.3e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Iso_dh PF00180.20 ORY80732.1 - 8.3e-102 340.9 0.0 1e-101 340.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase F-box-like PF12937.7 ORY80733.1 - 7.6e-09 35.3 1.8 1.7e-08 34.2 1.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY80733.1 - 0.0012 18.6 0.2 0.0039 17.0 0.2 1.9 1 1 0 1 1 1 1 F-box domain DUF2152 PF10222.9 ORY80733.1 - 0.12 10.6 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Ribosomal_L7Ae PF01248.26 ORY80734.1 - 3.7e-29 100.3 3.2 5.6e-29 99.7 3.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Med21 PF11221.8 ORY80735.1 - 1.8e-25 89.9 5.6 2.4e-25 89.5 5.6 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex CTP_transf_like PF01467.26 ORY80735.1 - 0.0038 17.4 0.1 0.0047 17.1 0.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Mt_ATP_synt PF15704.5 ORY80735.1 - 0.015 15.2 1.0 0.018 14.9 0.3 1.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase subunit V-SNARE_C PF12352.8 ORY80735.1 - 0.21 11.9 1.1 0.75 10.1 0.1 2.4 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus OmpH PF03938.14 ORY80735.1 - 0.27 11.5 6.0 0.16 12.3 4.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 ORY80735.1 - 0.33 11.0 5.4 0.43 10.7 5.4 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Coatomer_WDAD PF04053.14 ORY80737.1 - 5e-158 526.8 0.0 1.7e-157 525.0 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 ORY80737.1 - 1e-37 127.4 7.4 2.2e-07 31.4 0.2 8.5 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY80737.1 - 4.4e-10 39.7 0.2 0.057 13.7 0.0 6.3 4 1 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY80737.1 - 0.022 14.6 0.4 8.5 6.2 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY80737.1 - 0.14 10.8 1.2 1.5 7.3 0.2 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Sec2p PF06428.11 ORY80738.1 - 0.24 11.4 6.1 0.065 13.2 0.8 2.7 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Bromodomain PF00439.25 ORY80739.1 - 1.1e-26 92.7 0.1 1.4e-13 50.7 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 ORY80739.1 - 1.4e-15 57.2 0.1 2.4e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 BAH domain SIMPL PF04402.14 ORY80739.1 - 0.0013 19.3 2.8 0.56 10.6 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF541) DUF2514 PF10721.9 ORY80739.1 - 0.061 13.4 17.5 0.3 11.1 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) zf-CCCH PF00642.24 ORY80740.1 - 6.3e-18 64.2 14.9 1.8e-11 43.7 1.5 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY80740.1 - 1.9e-11 43.5 14.4 1.6e-07 31.0 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY80740.1 - 5.8e-10 38.9 15.8 7e-08 32.3 3.8 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 ORY80740.1 - 0.0023 18.3 0.2 0.0023 18.3 0.2 2.7 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY80740.1 - 0.018 15.7 11.7 0.49 11.1 1.6 2.0 1 1 1 2 2 2 0 Torus domain Defensin_int PF17858.1 ORY80740.1 - 0.023 14.7 4.3 0.049 13.6 1.3 2.1 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide oligo_HPY PF08352.12 ORY80740.1 - 2.8 8.5 8.7 5.2 7.7 1.2 2.1 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCHH PF10283.9 ORY80740.1 - 3.4 7.7 15.9 2.2 8.4 1.6 3.0 3 0 0 3 3 3 0 PBZ domain DIOX_N PF14226.6 ORY80742.1 - 7.2e-06 26.8 0.0 1.1e-05 26.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY80742.1 - 0.04 14.4 0.0 0.73 10.4 0.0 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 ORY80744.1 - 6.5e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY80744.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain Cpn60_TCP1 PF00118.24 ORY80745.1 - 4.5e-132 441.1 16.3 6.7e-132 440.6 16.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 ORY80745.1 - 0.0063 16.0 0.2 0.03 13.8 0.1 2.0 2 0 0 2 2 2 1 Telomere recombination DUF2326 PF10088.9 ORY80745.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) Rrp15p PF07890.12 ORY80746.1 - 3.8e-18 66.1 10.2 1.6e-17 64.1 10.2 2.0 1 1 0 1 1 1 1 Rrp15p Nop14 PF04147.12 ORY80746.1 - 0.00087 17.6 4.6 0.00087 17.6 4.6 1.9 2 0 0 2 2 2 1 Nop14-like family SDA1 PF05285.12 ORY80746.1 - 0.0045 16.5 4.9 0.0045 16.5 4.9 2.2 2 0 0 2 2 2 1 SDA1 Sporozoite_P67 PF05642.11 ORY80746.1 - 0.027 12.6 6.0 0.05 11.7 6.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 ORY80746.1 - 0.21 11.6 7.7 0.12 12.4 3.2 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal BUD22 PF09073.10 ORY80746.1 - 0.23 10.8 19.6 0.15 11.4 9.9 2.4 3 0 0 3 3 3 0 BUD22 FYDLN_acid PF09538.10 ORY80746.1 - 0.39 11.4 16.7 0.82 10.4 10.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.14 ORY80746.1 - 0.6 8.3 14.0 0.0098 14.2 4.7 1.9 2 0 0 2 2 2 0 CDC45-like protein Myc_N PF01056.18 ORY80746.1 - 1.3 8.9 9.9 0.036 14.0 3.0 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Sigma70_ner PF04546.13 ORY80746.1 - 2 8.2 16.2 13 5.6 12.7 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 ORY80746.1 - 2.1 8.6 19.9 8.1 6.6 0.9 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.10 ORY80746.1 - 3 8.1 9.5 1.7 8.9 3.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.13 ORY80746.1 - 4.1 5.4 23.6 0.14 10.2 17.1 1.8 2 0 0 2 2 2 0 DNA polymerase phi RRN3 PF05327.11 ORY80746.1 - 4.4 5.7 10.7 7.4 5.0 10.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC27 PF09507.10 ORY80746.1 - 4.8 6.4 20.0 2.6 7.3 11.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 BSP_II PF05432.11 ORY80746.1 - 6.2 6.4 19.4 5.2 6.7 10.6 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Cwf_Cwc_15 PF04889.12 ORY80746.1 - 7.3 6.2 25.8 0.036 13.8 10.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CPSF100_C PF13299.6 ORY80746.1 - 9.2 6.4 9.1 5.6 7.1 2.6 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal CK2S PF15011.6 ORY80747.1 - 0.00043 20.2 0.8 0.00059 19.8 0.8 1.2 1 0 0 1 1 1 1 Casein Kinase 2 substrate Lipoprotein_7 PF01540.16 ORY80747.1 - 0.00089 18.6 3.1 0.001 18.4 3.1 1.1 1 0 0 1 1 1 1 Adhesin lipoprotein Apolipoprotein PF01442.18 ORY80747.1 - 0.001 19.0 9.6 0.0017 18.3 9.6 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 ORY80747.1 - 0.0015 18.1 4.7 0.0049 16.4 1.4 2.1 1 1 1 2 2 2 1 fzo-like conserved region Sec8_exocyst PF04048.14 ORY80747.1 - 0.0029 17.5 0.3 0.0037 17.1 0.3 1.3 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF4795 PF16043.5 ORY80747.1 - 0.0046 16.6 4.3 0.0077 15.9 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Prominin PF05478.11 ORY80747.1 - 0.0052 14.8 0.1 0.0056 14.7 0.1 1.1 1 0 0 1 1 1 1 Prominin Zw10 PF06248.13 ORY80747.1 - 0.0053 15.4 1.7 0.0064 15.1 1.7 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 T3SSipB PF16535.5 ORY80747.1 - 0.012 16.1 0.3 0.015 15.8 0.3 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB RE_Alw26IDE PF09665.10 ORY80747.1 - 0.015 14.5 1.0 0.018 14.2 1.0 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) DUF2130 PF09903.9 ORY80747.1 - 0.016 14.5 5.4 0.037 13.3 5.4 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF3584 PF12128.8 ORY80747.1 - 0.021 12.4 7.4 0.025 12.1 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ApoLp-III PF07464.11 ORY80747.1 - 0.034 14.2 2.2 0.044 13.9 2.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) TPR_MLP1_2 PF07926.12 ORY80747.1 - 0.036 14.1 7.8 0.058 13.5 7.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Allexi_40kDa PF05549.11 ORY80747.1 - 0.037 13.5 0.6 5.9 6.3 0.0 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Nup88 PF10168.9 ORY80747.1 - 0.052 11.4 3.5 0.069 11.0 3.5 1.2 1 0 0 1 1 1 0 Nuclear pore component CREPT PF16566.5 ORY80747.1 - 0.053 13.7 4.3 0.053 13.7 1.2 2.1 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour NPV_P10 PF05531.12 ORY80747.1 - 0.055 13.9 0.8 10 6.7 0.5 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_11 PF13086.6 ORY80747.1 - 0.059 13.1 3.0 0.078 12.7 3.0 1.1 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 ORY80747.1 - 0.06 13.7 1.1 0.47 10.8 0.6 2.4 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1451 PF07295.11 ORY80747.1 - 0.061 13.4 3.0 0.049 13.7 1.5 1.5 1 1 0 1 1 1 0 Zinc-ribbon containing domain FAM184 PF15665.5 ORY80747.1 - 0.063 13.0 8.5 0.086 12.6 8.5 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B LXG PF04740.12 ORY80747.1 - 0.076 12.7 2.9 0.16 11.6 2.9 1.6 1 1 0 1 1 1 0 LXG domain of WXG superfamily MttA_Hcf106 PF02416.16 ORY80747.1 - 0.083 12.2 3.5 0.2 11.0 3.5 1.7 1 1 0 1 1 1 0 mttA/Hcf106 family Nup54 PF13874.6 ORY80747.1 - 0.089 12.9 3.7 0.32 11.1 0.1 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.12 ORY80747.1 - 0.099 12.7 4.3 0.18 11.9 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 ORY80747.1 - 0.12 12.6 4.4 0.14 12.3 0.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family COG2 PF06148.11 ORY80747.1 - 0.12 12.4 4.7 0.1 12.7 2.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ALIX_LYPXL_bnd PF13949.6 ORY80747.1 - 0.13 11.6 7.8 0.12 11.7 4.5 2.0 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Occludin_ELL PF07303.13 ORY80747.1 - 0.13 13.0 6.2 0.66 10.7 5.6 2.1 1 1 1 2 2 2 0 Occludin homology domain YtxH PF12732.7 ORY80747.1 - 0.15 12.6 8.8 1.8 9.1 3.1 2.5 1 1 1 2 2 2 0 YtxH-like protein OmpH PF03938.14 ORY80747.1 - 0.16 12.3 8.4 0.13 12.6 2.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) YabA PF06156.13 ORY80747.1 - 0.16 12.6 2.4 0.31 11.7 1.8 1.8 1 1 0 1 1 1 0 Initiation control protein YabA PhoU PF01895.19 ORY80747.1 - 0.16 12.4 2.0 0.29 11.6 2.0 1.4 1 0 0 1 1 1 0 PhoU domain Exonuc_VII_L PF02601.15 ORY80747.1 - 0.16 11.5 4.5 0.25 10.9 4.5 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 ORY80747.1 - 0.22 10.4 8.5 0.081 11.8 4.5 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein CdvA PF18822.1 ORY80747.1 - 0.24 11.2 12.0 0.87 9.4 2.8 2.5 2 1 1 3 3 2 0 CdvA-like coiled-coil domain KxDL PF10241.9 ORY80747.1 - 0.27 11.5 5.6 2.2 8.6 0.4 2.7 2 1 1 3 3 2 0 Uncharacterized conserved protein Vps54_N PF10475.9 ORY80747.1 - 0.37 10.0 2.0 0.47 9.7 2.0 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Atg14 PF10186.9 ORY80747.1 - 0.37 9.8 5.6 0.47 9.5 5.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 ORY80747.1 - 0.45 10.9 6.9 25 5.4 3.9 3.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 ORY80747.1 - 0.47 9.8 5.4 2 7.7 5.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1351 PF07083.11 ORY80747.1 - 0.54 10.0 9.1 0.63 9.8 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) Mt_ATP-synt_D PF05873.12 ORY80747.1 - 0.56 10.1 5.0 2.2 8.1 1.2 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.9 ORY80747.1 - 0.59 10.7 7.4 1.7 9.2 7.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Csm1_N PF18504.1 ORY80747.1 - 0.6 10.5 8.1 4.3 7.7 0.9 2.8 2 1 0 2 2 2 0 Csm1 N-terminal domain POTRA_TamA_1 PF17243.2 ORY80747.1 - 0.63 10.2 5.4 4.7 7.4 0.6 2.4 2 0 0 2 2 2 0 POTRA domain TamA domain 1 DUF16 PF01519.16 ORY80747.1 - 0.66 10.5 8.9 15 6.1 8.9 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 V_ATPase_I PF01496.19 ORY80747.1 - 0.67 7.8 3.0 0.79 7.6 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spectrin PF00435.21 ORY80747.1 - 0.78 10.2 6.1 17 6.0 6.0 2.5 1 1 0 1 1 1 0 Spectrin repeat Spore_III_AB PF09548.10 ORY80747.1 - 0.89 9.6 4.1 1.4 9.0 0.3 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Prefoldin_2 PF01920.20 ORY80747.1 - 1.2 9.1 9.7 4.4 7.3 6.1 2.8 1 1 1 2 2 2 0 Prefoldin subunit DUF883 PF05957.13 ORY80747.1 - 1.2 9.7 9.6 6.3 7.5 7.6 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Grg1 PF11034.8 ORY80747.1 - 1.3 9.2 6.7 1.1 9.6 4.3 2.1 1 1 1 2 2 2 0 Glucose-repressible protein Grg1 DUF2203 PF09969.9 ORY80747.1 - 1.5 9.5 8.6 2.9 8.7 3.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 ORY80747.1 - 1.7 7.8 4.9 2.4 7.3 4.5 1.4 1 1 0 1 1 1 0 TMPIT-like protein YkyA PF10368.9 ORY80747.1 - 3.3 7.4 10.8 1.6 8.4 8.5 1.7 2 1 0 2 2 1 0 Putative cell-wall binding lipoprotein HIP1_clath_bdg PF16515.5 ORY80747.1 - 4.5 8.0 11.6 1.1 9.9 3.6 2.5 1 1 2 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 XhlA PF10779.9 ORY80747.1 - 8.4 6.7 11.7 83 3.5 1.0 3.8 1 1 3 4 4 4 0 Haemolysin XhlA ABC_membrane PF00664.23 ORY80748.1 - 1.4e-79 267.6 29.8 8.5e-42 143.7 9.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY80748.1 - 3.7e-54 183.0 0.1 2.7e-30 105.7 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY80748.1 - 3.1e-09 36.6 0.0 0.00058 19.4 0.0 3.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY80748.1 - 2.5e-06 27.5 0.7 0.016 15.1 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY80748.1 - 1.2e-05 25.8 1.9 0.083 13.3 0.2 2.8 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY80748.1 - 2.7e-05 24.2 0.4 0.072 13.2 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY80748.1 - 0.00092 19.3 1.4 0.031 14.3 0.0 2.9 3 0 0 3 3 3 1 Dynamin family Zeta_toxin PF06414.12 ORY80748.1 - 0.0013 18.0 1.3 0.21 10.9 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 ORY80748.1 - 0.005 16.5 1.3 0.85 9.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY80748.1 - 0.048 13.5 0.3 9.8 5.9 0.0 3.7 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 ORY80748.1 - 0.077 12.0 1.6 5.7 5.8 0.2 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORY80748.1 - 0.079 12.7 2.6 2.4 7.9 0.2 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY80748.1 - 0.11 12.2 0.4 18 5.0 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 ORY80748.1 - 0.14 11.2 0.4 5.3 6.0 0.1 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 ORY80748.1 - 0.22 11.6 6.0 1.2 9.2 0.1 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain DUF815 PF05673.13 ORY80748.1 - 0.27 10.3 1.4 12 4.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY80748.1 - 0.58 9.6 3.1 7.4 6.0 0.1 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_25 PF13481.6 ORY80748.1 - 1.1 8.8 3.9 2.3 7.8 0.4 2.6 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 ORY80748.1 - 1.4 9.4 4.0 47 4.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 ORY80748.1 - 2.3 8.5 6.9 6.6 7.0 0.3 3.4 3 0 0 3 3 3 0 AAA domain VIT1 PF01988.19 ORY80749.1 - 7.3e-64 215.6 3.0 8.9e-64 215.3 3.0 1.1 1 0 0 1 1 1 1 VIT family NAD_binding_6 PF08030.12 ORY80750.1 - 2.5e-31 108.9 0.0 4.3e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY80750.1 - 3.4e-23 81.8 0.0 7.4e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 ORY80750.1 - 8.8e-18 64.6 16.4 6.6e-17 61.8 11.3 2.4 2 0 0 2 2 2 2 Ferric reductase like transmembrane component CheB_methylest PF01339.17 ORY80750.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 CheB methylesterase DUF420 PF04238.12 ORY80750.1 - 8.1 6.7 10.0 1.7 8.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF420) DUF1677 PF07911.13 ORY80751.1 - 0.014 15.7 0.1 0.041 14.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) GN3L_Grn1 PF08701.11 ORY80752.1 - 7.4e-22 77.2 11.3 7.4e-22 77.2 11.3 2.6 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 ORY80752.1 - 4.5e-16 58.9 0.1 2.1e-13 50.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY80752.1 - 3.4e-08 33.1 0.0 1.2e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY80752.1 - 1.5e-06 28.2 0.0 0.012 15.6 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY80752.1 - 0.00019 21.1 0.1 0.46 10.0 0.0 3.2 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 ORY80752.1 - 0.053 14.0 0.5 1.8 9.1 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Arf PF00025.21 ORY80752.1 - 0.061 12.8 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 ORY80752.1 - 0.089 13.0 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORY80752.1 - 2.6 8.1 6.5 0.54 10.3 0.1 3.0 4 1 0 4 4 4 0 Dynamin family DUF4604 PF15377.6 ORY80753.1 - 3.1e-18 66.8 12.0 4.8e-18 66.2 12.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) LIM_bind PF01803.16 ORY80753.1 - 0.15 11.6 0.5 0.22 11.0 0.5 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Peptidase_S49_N PF08496.10 ORY80753.1 - 1.5 8.8 7.6 1 9.4 5.3 1.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SRP-alpha_N PF04086.13 ORY80753.1 - 3.3 7.6 12.1 4.4 7.1 12.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Polysacc_deac_1 PF01522.21 ORY80754.1 - 1.9e-22 79.5 0.0 3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase nec1 PF10379.9 ORY80754.1 - 0.083 12.4 0.1 0.22 11.0 0.1 1.8 1 0 0 1 1 1 0 Virulence protein nec1 Polysacc_deac_1 PF01522.21 ORY80755.1 - 6.6e-20 71.2 0.0 1.1e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase TFIIF_alpha PF05793.12 ORY80757.1 - 1.1e-05 24.3 13.7 1.1e-05 24.3 13.7 3.5 2 2 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF5643 PF18705.1 ORY80757.1 - 0.078 13.0 1.7 17 5.5 2.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Amino_oxidase PF01593.24 ORY80758.1 - 4.6e-44 151.5 0.1 8.6e-31 107.7 0.2 2.0 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY80758.1 - 5.5e-12 45.7 0.0 1.2e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY80758.1 - 0.0001 22.0 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY80758.1 - 0.02 14.0 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ORY80758.1 - 0.023 13.4 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ORY80758.1 - 0.16 11.2 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family DEAD PF00270.29 ORY80759.1 - 4.3e-49 166.7 0.0 6.8e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY80759.1 - 6.4e-30 103.8 0.0 9.9e-29 99.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY80759.1 - 1.9e-06 28.0 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY80759.1 - 0.15 10.8 0.0 1.9 7.2 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 ORY80759.1 - 0.24 10.7 0.0 0.45 9.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit 2OG-FeII_Oxy_2 PF13532.6 ORY80761.1 - 3.2e-15 56.8 0.0 3.9e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CDC14 PF08045.11 ORY80762.1 - 8.4e-38 130.1 7.8 1.8e-17 63.4 0.0 3.9 3 1 1 4 4 4 4 Cell division control protein 14, SIN component MAP65_ASE1 PF03999.12 ORY80762.1 - 2.3 6.8 5.6 3.2 6.3 5.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Sugar_tr PF00083.24 ORY80763.1 - 5.6e-93 312.3 23.9 6.7e-93 312.0 23.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY80763.1 - 3.9e-19 68.8 25.7 3.9e-19 68.8 25.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY80763.1 - 0.0059 15.0 1.6 0.0059 15.0 1.6 1.8 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CDC14 PF08045.11 ORY80764.1 - 1.4e-18 67.0 0.4 4.6e-12 45.6 0.0 2.5 2 1 0 2 2 2 2 Cell division control protein 14, SIN component CRAL_TRIO PF00650.20 ORY80765.1 - 6.8e-35 120.1 0.0 9.3e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY80765.1 - 2.9e-09 37.0 0.9 1e-08 35.2 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain BTB_2 PF02214.22 ORY80767.1 - 0.0016 18.8 0.0 0.0032 17.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Ribonucleas_3_3 PF14622.6 ORY80768.1 - 0.00043 20.4 0.0 0.00075 19.7 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 ORY80768.1 - 0.0091 16.7 0.2 0.12 13.0 0.1 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif GYF PF02213.16 ORY80770.1 - 4.6e-18 64.6 0.6 1.1e-17 63.4 0.6 1.7 1 0 0 1 1 1 1 GYF domain Hist_deacetyl PF00850.19 ORY80772.1 - 1.5e-83 280.9 0.0 2e-83 280.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Arrestin_N PF00339.29 ORY80773.1 - 1e-06 28.9 0.0 2.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sugar_tr PF00083.24 ORY80774.1 - 9e-113 377.5 22.5 1.8e-112 376.5 22.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY80774.1 - 7.8e-29 100.7 51.0 2.1e-19 69.7 15.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ECM11 PF15463.6 ORY80775.1 - 3e-05 24.6 9.4 0.00011 22.8 9.5 1.9 1 1 0 1 1 1 1 Extracellular mutant protein 11 Snf7 PF03357.21 ORY80775.1 - 0.00014 21.5 0.7 0.00024 20.7 0.7 1.2 1 0 0 1 1 1 1 Snf7 HAUS6_N PF14661.6 ORY80775.1 - 0.013 15.1 0.4 0.013 15.1 0.4 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HrpB7 PF09486.10 ORY80775.1 - 0.028 14.8 1.6 0.2 12.0 0.7 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4559 PF15112.6 ORY80775.1 - 0.13 11.9 3.1 0.15 11.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Arrestin_N PF00339.29 ORY80777.1 - 6e-08 32.9 0.0 5.3e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Utp12 PF04003.12 ORY80778.1 - 7.5e-23 80.9 0.3 1.2e-22 80.3 0.3 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 ORY80778.1 - 0.21 12.5 1.4 1.2 10.2 1.5 2.4 1 1 0 1 1 1 0 WD domain, G-beta repeat Med3 PF11593.8 ORY80778.1 - 2.7 7.1 5.1 5.4 6.1 5.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FA_hydroxylase PF04116.13 ORY81201.1 - 5.1e-20 72.2 15.3 5.1e-20 72.2 15.3 2.5 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 ORY81203.1 - 1.1e-35 123.2 44.2 1.1e-35 123.2 44.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY81203.1 - 5e-09 35.5 12.8 5e-09 35.5 12.8 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter DUF2721 PF11026.8 ORY81203.1 - 2.8 7.8 8.7 3.9 7.4 1.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) AA_permease_2 PF13520.6 ORY81204.1 - 1.7e-67 228.1 39.1 2.2e-67 227.8 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY81204.1 - 3.7e-17 62.1 35.2 4.7e-17 61.8 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease RCR PF12273.8 ORY81204.1 - 0.17 12.6 0.4 0.61 10.7 0.1 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red TFCD_C PF12612.8 ORY81205.1 - 1.9e-22 80.0 2.5 1.5e-21 77.1 0.0 3.9 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal Cnd1 PF12717.7 ORY81205.1 - 0.0011 19.1 0.0 0.15 12.1 0.0 3.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY81205.1 - 0.018 15.6 0.0 0.29 11.8 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 ORY81205.1 - 0.14 12.5 0.1 0.14 12.5 0.1 7.3 9 0 0 9 9 9 0 HEAT repeat YycC PF14174.6 ORY81205.1 - 0.16 11.8 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 YycC-like protein FeoB_Cyto PF17910.1 ORY81205.1 - 0.3 11.7 2.0 21 5.7 0.2 3.4 2 0 0 2 2 2 0 FeoB cytosolic helical domain SpoIIIAH PF12685.7 ORY81206.1 - 0.33 10.8 16.0 1.5 8.6 16.0 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein ECM1 PF05782.11 ORY81206.1 - 0.36 9.7 7.8 0.36 9.7 7.8 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) VIR_N PF15912.5 ORY81206.1 - 1.1 8.8 14.9 1.1 8.8 14.9 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal GAGA_bind PF06217.12 ORY81206.1 - 5.2 7.3 10.7 5.1 7.3 10.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.7 ORY81206.1 - 9.6 4.2 10.9 9.3 4.2 10.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Kelch_4 PF13418.6 ORY81208.1 - 4.1e-17 61.9 7.0 4.1e-07 29.9 0.0 6.2 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY81208.1 - 1.8e-14 53.6 6.8 0.0022 18.2 0.1 6.4 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY81208.1 - 5.3e-13 48.8 0.6 0.0009 19.4 0.1 5.7 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 ORY81208.1 - 5.4e-10 39.0 0.2 0.00073 19.5 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 ORY81208.1 - 5.5e-06 25.9 3.4 0.32 10.6 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 ORY81208.1 - 0.00064 19.6 0.4 0.68 10.0 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Zn_clus PF00172.18 ORY81210.1 - 1.7e-06 28.0 7.7 2.6e-06 27.5 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 ORY81210.1 - 0.15 12.0 0.1 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension adh_short PF00106.25 ORY81211.1 - 1.4e-39 135.6 0.0 1.7e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY81211.1 - 8.4e-29 100.8 0.0 1.1e-28 100.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY81211.1 - 3.5e-13 49.9 0.0 5.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY81211.1 - 1.2e-07 31.8 0.0 1.8e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY81211.1 - 1.9e-05 24.2 0.1 7.2e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY81211.1 - 0.00031 19.9 0.1 0.00065 18.9 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 ORY81211.1 - 0.018 14.6 0.1 2.8 7.4 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 ORY81211.1 - 0.032 13.2 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_tran_28_C PF04101.16 ORY81211.1 - 0.065 13.2 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain zf-C2H2 PF00096.26 ORY81212.1 - 9e-13 47.9 5.4 1.7e-05 25.0 0.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY81212.1 - 7.9e-07 29.2 0.2 0.0013 19.0 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY81212.1 - 3.6e-06 27.3 9.7 0.0064 17.2 0.4 3.0 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY81212.1 - 0.00039 20.7 0.9 0.33 11.4 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type GAGA PF09237.11 ORY81212.1 - 0.0034 17.1 3.7 0.0072 16.1 3.7 1.5 1 0 0 1 1 1 1 GAGA factor zf-C2H2_6 PF13912.6 ORY81212.1 - 0.013 15.4 9.7 0.055 13.5 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY81212.1 - 0.023 15.1 15.9 0.042 14.3 0.3 3.8 4 0 0 4 4 3 0 Zinc-finger double domain DZR PF12773.7 ORY81212.1 - 0.028 14.4 0.5 0.055 13.5 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon Rad50_zn_hook PF04423.14 ORY81212.1 - 0.046 13.6 0.3 0.1 12.4 0.3 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 ORY81212.1 - 0.059 13.5 1.3 0.11 12.6 1.3 1.4 1 0 0 1 1 1 0 Zinc ribbon domain C1_4 PF07975.12 ORY81212.1 - 0.15 12.3 0.5 0.94 9.8 0.8 2.1 1 1 1 2 2 2 0 TFIIH C1-like domain DUF2256 PF10013.9 ORY81212.1 - 0.31 11.2 2.6 0.39 10.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-Di19 PF05605.12 ORY81212.1 - 0.48 10.8 3.7 1 9.7 3.7 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Arrestin_N PF00339.29 ORY81213.1 - 1.5e-05 25.1 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY81213.1 - 0.036 13.8 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like EamA PF00892.20 ORY81216.1 - 1.3e-09 38.3 25.4 8.1e-08 32.5 8.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY81216.1 - 1.1e-07 31.4 9.2 1.4e-07 31.0 9.2 1.1 1 0 0 1 1 1 1 UAA transporter family Lipase_GDSL_2 PF13472.6 ORY81217.1 - 0.0018 18.7 0.0 0.0033 17.9 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY81217.1 - 0.04 13.9 0.0 0.064 13.2 0.0 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Fungal_trans_2 PF11951.8 ORY81218.1 - 1.7e-25 89.7 1.4 2.3e-25 89.2 1.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY81218.1 - 2.4e-06 27.6 8.3 4.6e-06 26.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ammonium_transp PF00909.21 ORY81220.1 - 7e-81 271.9 25.3 8.5e-81 271.7 25.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family MMS1_N PF10433.9 ORY81221.1 - 4.5e-72 243.2 0.0 7.5e-72 242.5 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY81221.1 - 1.1e-53 182.7 0.1 3.9e-53 180.9 0.0 2.0 3 0 0 3 3 3 1 CPSF A subunit region DUF111 PF01969.17 ORY81223.1 - 0.07 12.2 0.0 0.09 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 Heme_oxygenase PF01126.20 ORY81224.1 - 2.6e-37 128.6 0.5 3.6e-36 124.9 0.5 2.4 1 1 0 1 1 1 1 Heme oxygenase Transp_cyt_pur PF02133.15 ORY81225.1 - 1.4e-79 267.9 30.9 1.6e-79 267.7 30.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3810 PF12725.7 ORY81225.1 - 3.3 7.0 4.8 2 7.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) p450 PF00067.22 ORY81226.1 - 6.9e-67 226.2 0.0 8.5e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0728 PF15092.6 ORY81226.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 adh_short_C2 PF13561.6 ORY81227.1 - 4.2e-60 203.2 0.0 4.7e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY81227.1 - 4.4e-48 163.3 0.0 5.4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY81227.1 - 1e-08 35.3 0.4 1.7e-08 34.6 0.4 1.3 1 0 0 1 1 1 1 KR domain Arrestin_N PF00339.29 ORY81228.1 - 0.00063 19.8 0.0 0.0047 17.0 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HSF_DNA-bind PF00447.17 ORY81229.1 - 6.5e-18 65.1 0.0 1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding TMEM71 PF15121.6 ORY81229.1 - 0.0044 16.7 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 TMEM71 protein family HSF_DNA-bind PF00447.17 ORY81230.1 - 5.2e-15 55.8 0.0 8.7e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding NAM-associated PF14303.6 ORY81230.1 - 0.84 10.3 7.8 3.3 8.4 0.9 2.3 2 1 0 2 2 2 0 No apical meristem-associated C-terminal domain Hemerythrin PF01814.23 ORY81231.1 - 0.00042 20.9 3.2 0.00067 20.3 3.2 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain PCEMA1 PF07418.11 ORY81231.1 - 0.056 13.0 0.2 0.07 12.6 0.2 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 CHGN PF05679.16 ORY81231.1 - 0.065 12.1 0.3 0.077 11.8 0.3 1.1 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase RasGEF PF00617.19 ORY81232.1 - 8.1e-50 169.5 0.0 1.6e-49 168.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY81232.1 - 5.1e-21 74.9 0.3 1.4e-20 73.4 0.2 1.8 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 ORY81232.1 - 3.7e-13 49.1 0.0 6.9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY81232.1 - 3.8e-12 45.7 0.0 7.6e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY81232.1 - 1.9e-11 43.3 0.0 3.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain OHCU_decarbox PF09349.10 ORY81232.1 - 0.11 13.0 0.7 4 7.9 0.0 2.6 2 0 0 2 2 2 0 OHCU decarboxylase PMC2NT PF08066.12 ORY81232.1 - 0.22 12.2 5.5 3 8.6 0.1 4.1 4 1 1 5 5 5 0 PMC2NT (NUC016) domain Lipase_3 PF01764.25 ORY81234.1 - 4e-08 33.2 0.0 1.2e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) EBP50_C PF09007.11 ORY81234.1 - 2 9.4 9.0 3.8 8.5 2.5 2.3 2 0 0 2 2 2 0 EBP50, C-terminal MFS_1 PF07690.16 ORY81238.1 - 7.5e-23 81.0 23.9 7.5e-23 81.0 23.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY81238.1 - 4.9e-07 29.0 8.1 1.1e-06 27.9 7.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 ORY81238.1 - 1.6e-06 27.0 0.3 1.6e-06 27.0 0.3 3.0 4 0 0 4 4 4 1 MFS/sugar transport protein TRI12 PF06609.13 ORY81238.1 - 2.5e-05 22.9 1.7 3.5e-05 22.4 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mannosyl_trans3 PF11051.8 ORY81239.1 - 5.6e-23 81.7 0.0 4.6e-11 42.6 0.0 3.1 3 0 0 3 3 3 3 Mannosyltransferase putative 2-Hacid_dh_C PF02826.19 ORY81240.1 - 1.2e-44 151.7 0.1 3.2e-43 147.2 0.1 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY81240.1 - 1.5e-24 86.2 0.0 1.8e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ThiF PF00899.21 ORY81240.1 - 0.21 10.9 1.8 0.52 9.6 1.8 1.5 1 0 0 1 1 1 0 ThiF family NTP_transferase PF00483.23 ORY81241.1 - 1.6e-45 155.6 0.0 2.7e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORY81241.1 - 1.1e-09 37.6 11.1 4.8e-06 26.1 1.3 4.1 1 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY81241.1 - 7.2e-06 26.5 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 ORY81241.1 - 0.081 11.0 0.1 0.11 10.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 ORY81241.1 - 1.8 8.4 6.8 0.99 9.2 1.2 2.8 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase YTH PF04146.15 ORY81242.1 - 5.2e-46 156.6 0.0 9.8e-46 155.7 0.0 1.5 1 0 0 1 1 1 1 YT521-B-like domain TMEM234 PF10639.9 ORY81246.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative transmembrane family 234 GDP_Man_Dehyd PF16363.5 ORY81247.1 - 1.3e-157 524.5 0.0 1.4e-157 524.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY81247.1 - 5e-73 245.5 0.0 6.8e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY81247.1 - 3.4e-06 26.4 0.0 6.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ORY81247.1 - 0.00019 21.0 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY81247.1 - 0.00046 19.4 0.0 0.00085 18.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Nucleotid_trans PF03407.16 ORY81248.1 - 7.7e-34 117.5 0.0 1.3e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase O-FucT PF10250.9 ORY81248.1 - 8.1e-16 58.6 0.0 4.2e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Mt_ATP-synt_D PF05873.12 ORY81248.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF5060 PF16586.5 ORY81252.1 - 0.088 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) DUF3984 PF13136.6 ORY81252.1 - 0.12 11.7 2.1 0.17 11.3 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Filamin PF00630.19 ORY81252.1 - 0.15 12.9 0.0 0.28 12.0 0.0 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF3040 PF11239.8 ORY81253.1 - 0.15 12.3 2.5 0.8 10.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Glyco_transf_64 PF09258.10 ORY81254.1 - 2.8e-53 180.7 0.0 4.2e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_92 PF01697.27 ORY81255.1 - 5.5e-08 32.8 0.0 2.3e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 ORY81255.1 - 0.0047 17.4 0.0 0.039 14.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Lipase_GDSL_2 PF13472.6 ORY81256.1 - 5.7e-09 36.6 0.2 9.3e-09 35.9 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY81256.1 - 0.0005 20.1 0.0 0.00084 19.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF982 PF06169.12 ORY81256.1 - 0.073 13.1 1.4 9.6 6.3 0.0 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF982) Glyco_transf_10 PF00852.19 ORY81257.1 - 4.3e-17 62.4 0.0 1.4e-16 60.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Asp5 PF17000.5 ORY81258.1 - 0.16 12.1 0.2 0.47 10.6 0.1 1.8 1 1 1 2 2 2 0 Accessory secretory protein Sec, Asp5 DUF3704 PF12488.8 ORY81259.1 - 1.2 8.9 4.4 2.5 7.8 4.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) DEC-1_N PF04625.13 ORY81260.1 - 0.0063 15.6 2.8 0.0063 15.6 2.8 1.8 2 0 0 2 2 2 1 DEC-1 protein, N-terminal region SWIM PF04434.17 ORY81264.1 - 0.15 11.8 0.3 0.33 10.7 0.3 1.5 1 0 0 1 1 1 0 SWIM zinc finger Amidohydro_3 PF07969.11 ORY81265.1 - 4.4e-09 36.3 0.4 6.9e-08 32.4 0.4 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY81265.1 - 0.055 12.8 0.1 0.073 12.4 0.1 1.2 1 0 0 1 1 1 0 Amidohydrolase family Glyco_transf_64 PF09258.10 ORY81267.1 - 5.9e-27 94.5 0.0 7.7e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_transf_43 PF03360.16 ORY81268.1 - 2.2e-33 115.9 0.0 3.3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 Glycos_transf_2 PF00535.26 ORY81268.1 - 0.078 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 PS_pyruv_trans PF04230.13 ORY81271.1 - 7.5e-24 85.1 0.0 1.3e-15 58.1 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide pyruvyl transferase AA_kinase PF00696.28 ORY81271.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family Asp5 PF17000.5 ORY81272.1 - 0.031 14.4 0.1 0.084 13.0 0.1 1.7 1 1 0 1 1 1 0 Accessory secretory protein Sec, Asp5 RdDM_RDM1 PF09187.10 ORY81274.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 Zwint PF15556.6 ORY81275.1 - 0.16 11.4 1.8 0.22 11.0 1.8 1.1 1 0 0 1 1 1 0 ZW10 interactor Nucleotid_trans PF03407.16 ORY81276.1 - 1.9e-33 116.2 0.0 4.5e-33 115.0 0.0 1.6 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase O-FucT PF10250.9 ORY81276.1 - 4e-16 59.7 0.0 8.8e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Nucleotid_trans PF03407.16 ORY81277.1 - 8.1e-35 120.7 0.0 2e-34 119.4 0.0 1.7 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase O-FucT PF10250.9 ORY81277.1 - 8.8e-17 61.8 0.0 1.2e-15 58.1 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_10 PF00852.19 ORY81278.1 - 1.4e-17 64.0 0.0 3.7e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term TGBp3 PF02495.17 ORY81278.1 - 0.62 9.8 1.9 2.2 8.0 0.1 2.2 2 0 0 2 2 2 0 Triple gene block 3 PC-Esterase PF13839.6 ORY81280.1 - 3.8e-23 82.6 1.4 1.2e-10 41.7 0.0 2.3 1 1 1 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ost5 PF05251.12 ORY81280.1 - 0.19 12.0 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 PC-Esterase PF13839.6 ORY81281.1 - 4.7e-21 75.8 0.1 2e-20 73.7 0.1 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PMR5N PF14416.6 ORY81281.1 - 0.1 13.0 0.9 0.27 11.6 0.9 1.8 1 0 0 1 1 1 0 PMR5 N terminal Domain Fungal_trans_2 PF11951.8 ORY81283.1 - 7.6e-20 71.1 0.0 1.1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY81283.1 - 3.4e-05 23.9 7.8 5.7e-05 23.2 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PNRC PF15365.6 ORY81283.1 - 0.0032 17.2 3.8 0.0032 17.2 3.8 3.2 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif Flavin_Reduct PF01613.18 ORY81284.1 - 4.6e-17 62.5 0.0 6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain MFS_1 PF07690.16 ORY81285.1 - 5.2e-20 71.7 34.0 5.2e-20 71.7 34.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4271 PF14093.6 ORY81285.1 - 2.5 7.9 9.9 0.2 11.6 0.6 3.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4271) Amidohydro_3 PF07969.11 ORY81286.1 - 4.4e-76 257.3 3.3 5e-76 257.1 3.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY81286.1 - 5.6e-12 45.6 0.3 5.6e-07 29.2 0.1 3.3 2 1 0 2 2 2 2 Amidohydrolase family AA_permease PF00324.21 ORY81287.1 - 2.6e-113 379.2 36.6 3.1e-79 266.8 21.5 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 ORY81287.1 - 4e-31 108.3 35.8 8.7e-29 100.6 35.8 2.0 1 1 0 1 1 1 1 Amino acid permease Pox_A14 PF05767.12 ORY81287.1 - 4.6 7.5 7.8 5.4 7.3 0.6 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Cu_amine_oxid PF01179.20 ORY81288.1 - 2.3e-152 507.7 0.0 2.8e-152 507.4 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ORY81288.1 - 1e-06 28.8 0.0 3e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 ORY81288.1 - 6.4e-06 26.5 0.0 0.00028 21.2 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain DUF2169 PF09937.9 ORY81288.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Copper-fist PF00649.18 ORY81290.1 - 4.7e-22 77.2 0.9 9.1e-22 76.3 0.9 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain zf-TFIIB PF13453.6 ORY81290.1 - 0.071 12.5 1.7 0.15 11.4 1.7 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_clus PF00172.18 ORY81291.1 - 1.5e-06 28.2 6.2 2.2e-06 27.7 6.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY81292.1 - 4.4e-33 114.6 0.0 5.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY81292.1 - 0.00031 20.8 5.5 0.00051 20.1 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain O-FucT PF10250.9 ORY81293.1 - 4.3e-05 23.4 0.1 0.00019 21.3 0.1 1.9 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EHN PF06441.12 ORY81294.1 - 4.6e-32 110.6 0.1 7.5e-32 109.9 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY81294.1 - 1.6e-11 44.3 0.1 3.6e-11 43.2 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY81294.1 - 1.9e-06 28.6 0.0 4.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family MIP PF00230.20 ORY81295.1 - 3.7e-32 111.9 18.0 9e-32 110.6 18.0 1.5 1 1 0 1 1 1 1 Major intrinsic protein PRA1 PF03208.19 ORY81295.1 - 5.2 6.7 7.8 40 3.8 7.1 2.3 1 1 1 2 2 2 0 PRA1 family protein Fungal_trans PF04082.18 ORY81296.1 - 3.6e-05 22.9 0.4 5.2e-05 22.4 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY81296.1 - 0.00075 19.6 9.0 0.0012 18.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY81297.1 - 0.00012 21.2 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY81297.1 - 0.087 13.0 8.9 0.16 12.1 8.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_desaturase PF00487.24 ORY81298.1 - 6.9e-30 104.7 18.4 9.7e-30 104.2 18.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ORY81298.1 - 1.6e-07 31.6 0.0 3.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) FA_desaturase PF00487.24 ORY81299.1 - 1.7e-22 80.5 20.9 1.7e-22 80.5 20.9 2.2 1 1 1 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.8 ORY81299.1 - 4e-06 27.1 0.0 7.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) AA_permease PF00324.21 ORY81300.1 - 4.8e-121 404.7 43.8 5.5e-121 404.5 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY81300.1 - 8.3e-33 113.8 51.6 1.1e-32 113.4 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease Myb_DNA-binding PF00249.31 ORY81301.1 - 2e-40 136.8 8.9 6.2e-14 51.9 0.7 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY81301.1 - 7.6e-29 99.7 0.0 2.1e-10 40.7 0.0 3.9 3 1 1 4 4 4 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY81301.1 - 0.0001 22.5 2.8 0.014 15.7 0.2 2.9 2 1 1 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 ORY81301.1 - 0.0086 16.1 0.4 12 6.1 0.0 3.2 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 ORY81301.1 - 0.016 15.6 4.6 0.39 11.1 0.2 3.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORY81301.1 - 0.07 13.2 0.4 2.1 8.5 0.1 3.0 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Cu_amine_oxid PF01179.20 ORY81302.1 - 1e-152 508.8 0.0 1.3e-152 508.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 ORY81302.1 - 6.4e-09 36.1 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Glyco_hydro_28 PF00295.17 ORY81303.1 - 1.9e-46 158.6 10.8 1.9e-46 158.6 10.8 1.5 1 1 1 2 2 2 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 ORY81304.1 - 1.1e-46 158.9 3.1 1.4e-46 158.6 3.1 1.1 1 0 0 1 1 1 1 Pectinesterase E1-N PF14463.6 ORY81306.1 - 0.0043 16.9 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 E1 N-terminal domain KA1 PF02149.19 ORY81306.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 Acatn PF13000.7 ORY81307.1 - 3e-171 570.6 27.5 6.8e-89 298.8 16.3 3.6 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 BT1 PF03092.16 ORY81307.1 - 0.0048 15.2 0.1 0.0079 14.5 0.1 1.3 1 0 0 1 1 1 1 BT1 family Histone PF00125.24 ORY81309.1 - 3.7e-27 95.3 0.0 3.2e-26 92.2 0.0 2.1 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 ORY81309.1 - 0.16 12.6 1.1 0.21 12.2 1.1 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain IATP PF04568.12 ORY81309.1 - 9.1 6.8 7.2 20 5.7 6.3 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-CCHC PF00098.23 ORY81310.1 - 0.00016 21.6 7.0 0.00027 20.9 7.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 ORY81310.1 - 4.1 7.3 6.3 13 5.7 6.3 1.9 1 0 0 1 1 1 0 Zinc knuckle GCV_T PF01571.21 ORY81734.1 - 1.1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Actin PF00022.19 ORY81735.1 - 7.9e-125 416.7 0.0 9e-125 416.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY81735.1 - 0.0041 16.0 0.0 0.052 12.4 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein DUF4381 PF14316.6 ORY81736.1 - 0.014 15.6 1.2 0.028 14.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SKG6 PF08693.10 ORY81736.1 - 0.021 14.2 0.2 0.069 12.6 0.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MAP17 PF15807.5 ORY81736.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Mobilization_B PF17511.2 ORY81736.1 - 0.32 11.3 3.0 0.67 10.3 3.0 1.5 1 0 0 1 1 1 0 Mobilization protein B DUF202 PF02656.15 ORY81736.1 - 1.4 9.4 4.9 8.2 7.0 4.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 ORY81737.1 - 5.4e-28 97.9 27.8 5.4e-28 97.9 27.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5463 PF17551.2 ORY81737.1 - 0.2 11.6 1.9 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5463) CTP_transf_1 PF01148.20 ORY81738.1 - 0.01 15.6 3.8 0.015 15.1 3.8 1.3 1 1 0 1 1 1 0 Cytidylyltransferase family UQ_con PF00179.26 ORY81739.1 - 9.8e-51 171.1 0.0 1.1e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY81739.1 - 0.00095 18.9 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Amidohydro_2 PF04909.14 ORY81740.1 - 0.00054 19.8 0.0 0.02 14.7 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase DUF2423 PF10338.9 ORY81741.1 - 5.1e-13 49.0 6.4 9.4e-13 48.2 6.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.9 ORY81741.1 - 0.00075 20.1 2.5 0.0013 19.3 2.5 1.4 1 0 0 1 1 1 1 Learning-associated protein BLOC1S3 PF15753.5 ORY81741.1 - 0.19 11.8 3.0 0.25 11.5 3.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Ebp2 PF05890.12 ORY81742.1 - 9.1e-70 235.3 6.8 9.1e-70 235.3 6.8 2.0 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 PepSY_2 PF13670.6 ORY81742.1 - 5.3 7.1 7.0 2.2 8.3 3.7 2.0 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain WD40 PF00400.32 ORY81743.1 - 0.1 13.5 12.8 79 4.4 0.1 6.6 7 0 0 7 7 7 0 WD domain, G-beta repeat Nop PF01798.18 ORY81745.1 - 5.1e-62 209.4 0.0 7.2e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 ORY81745.1 - 1.9e-42 145.0 3.1 3.9e-42 144.0 3.1 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain RecC_C PF17946.1 ORY81745.1 - 0.13 12.0 0.2 0.31 10.8 0.1 1.7 2 0 0 2 2 2 0 RecC C-terminal domain PBP_like_2 PF12849.7 ORY81747.1 - 0.0028 17.4 0.2 0.0042 16.8 0.2 1.4 1 0 0 1 1 1 1 PBP superfamily domain YL1_C PF08265.11 ORY81749.1 - 3.8e-15 55.3 0.0 4.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain GPHH PF16905.5 ORY81749.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Ribonuclease_3 PF00636.26 ORY81751.1 - 3e-29 101.7 0.0 6.1e-15 55.7 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 ORY81751.1 - 1.2e-21 76.7 0.1 4.3e-21 74.9 0.1 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 ORY81751.1 - 7.2e-14 52.1 0.0 6.9e-06 26.3 0.0 4.0 3 1 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.29 ORY81751.1 - 1.2e-10 41.4 0.0 3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY81751.1 - 2.1e-08 34.3 0.0 5.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY81751.1 - 4.6e-08 33.4 0.0 8.6e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 ORY81751.1 - 3.8e-06 26.7 0.0 7.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 PAZ domain Mt_ATP-synt_D PF05873.12 ORY81752.1 - 1.3e-16 60.8 0.1 1.7e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF3251 PF11622.8 ORY81752.1 - 0.069 12.8 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) ApoLp-III PF07464.11 ORY81752.1 - 0.072 13.2 0.3 0.12 12.5 0.3 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Hydrolase_6 PF13344.6 ORY81753.1 - 7.3e-16 58.1 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY81753.1 - 2.9e-05 24.1 0.0 0.00015 21.7 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY81753.1 - 0.011 16.0 0.0 0.045 14.0 0.0 2.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase CUE PF02845.16 ORY81754.1 - 5.9e-09 35.5 0.0 1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 ORY81754.1 - 0.16 12.0 3.1 0.29 11.2 3.1 1.3 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 G2BR PF18442.1 ORY81754.1 - 0.7 9.6 6.5 1.2 8.8 6.5 1.3 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Semialdhyde_dhC PF02774.18 ORY81755.1 - 2.9e-36 125.3 0.0 4.7e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ORY81755.1 - 8.7e-31 106.9 0.0 1.6e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORY81755.1 - 0.055 13.4 0.0 0.26 11.1 0.0 2.1 1 1 0 1 1 1 0 NAD(P)H-binding Amidohydro_1 PF01979.20 ORY81756.1 - 8.5e-26 91.1 0.0 1.2e-25 90.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY81756.1 - 3.9e-12 46.4 0.1 1.4e-05 24.8 0.1 2.8 3 0 0 3 3 3 2 Amidohydrolase family Urease_alpha PF00449.20 ORY81756.1 - 0.0045 17.3 0.1 0.019 15.3 0.1 2.1 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Peptidase_M20 PF01546.28 ORY81757.1 - 4.6e-28 98.3 0.1 6.2e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY81757.1 - 0.00028 20.8 0.0 0.00064 19.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain SnoaL_4 PF13577.6 ORY81757.1 - 0.027 14.6 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain DIOX_N PF14226.6 ORY81759.1 - 1.5e-23 83.8 0.1 2.1e-23 83.3 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY81759.1 - 3.5e-21 75.6 0.0 5.4e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 ORY81760.1 - 1.3e-07 31.0 0.0 1.9e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY81760.1 - 0.016 15.3 7.1 0.028 14.5 7.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF484 PF04340.12 ORY81761.1 - 0.00088 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF484 TPR_2 PF07719.17 ORY81762.1 - 1.6e-11 43.3 2.0 0.0056 16.7 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY81762.1 - 2.1e-09 36.8 0.1 0.015 15.1 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY81762.1 - 5.9e-09 36.4 4.0 0.0055 17.3 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY81762.1 - 1.2e-07 31.9 14.2 0.00049 20.7 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY81762.1 - 2.1e-06 27.8 1.6 9.1e-05 22.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY81762.1 - 2.6e-06 27.6 3.3 2.2 8.6 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY81762.1 - 9.6e-05 22.8 0.0 1.3 9.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY81762.1 - 0.00099 19.3 0.0 0.41 11.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY81762.1 - 0.0025 17.9 0.0 6.6 7.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY81762.1 - 0.0053 16.7 3.5 31 4.9 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY81762.1 - 0.0057 17.2 0.2 41 5.1 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY81762.1 - 0.027 14.1 0.0 6.1 6.6 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 ORY81762.1 - 0.58 10.1 2.5 3.2 7.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldedh PF00171.22 ORY81763.1 - 1.3e-143 478.9 0.0 1.5e-143 478.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF433 PF04255.14 ORY81763.1 - 0.089 12.7 0.1 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF433) DUF4187 PF13821.6 ORY81764.1 - 3.5e-17 61.9 3.6 7e-17 61.0 3.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 ORY81764.1 - 3e-08 33.4 7.2 2.2e-06 27.5 2.2 2.9 3 0 0 3 3 3 2 G-patch domain G-patch_2 PF12656.7 ORY81764.1 - 0.0023 18.0 9.0 0.023 14.8 0.0 4.0 4 0 0 4 4 4 2 G-patch domain CN_hydrolase PF00795.22 ORY81765.1 - 2.6e-51 174.5 0.0 3e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase WD40 PF00400.32 ORY81766.1 - 6.9e-26 90.0 15.1 4.1e-05 24.2 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY81766.1 - 0.00046 20.4 0.0 1 9.7 0.1 4.2 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY81766.1 - 0.018 13.8 0.4 0.29 9.8 0.2 2.7 2 1 0 3 3 3 0 Nup133 N terminal like CLTH PF10607.9 ORY81767.1 - 2.8e-11 43.5 0.0 5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 ORY81767.1 - 1.4e-07 31.5 0.3 2.5e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY81767.1 - 0.0015 18.8 0.2 0.0027 18.0 0.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY81767.1 - 0.0056 16.6 0.2 0.0094 15.9 0.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.12 ORY81767.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_4 PF14447.6 ORY81767.1 - 0.12 12.3 0.5 0.27 11.1 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pellino PF04710.14 ORY81767.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Pellino Transp_cyt_pur PF02133.15 ORY81769.1 - 8.8e-35 120.3 36.3 1.2e-34 119.9 36.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin dCMP_cyt_deam_1 PF00383.23 ORY81770.1 - 3.4e-07 30.1 0.0 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY81770.1 - 5.4e-05 23.0 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORY81770.1 - 0.15 12.1 0.0 0.36 10.9 0.0 1.6 1 1 1 2 2 2 0 Bd3614-like deaminase Helicase_C PF00271.31 ORY81771.1 - 8.7e-05 22.8 0.0 0.00016 22.0 0.0 1.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Abhydrolase_3 PF07859.13 ORY81772.1 - 1.5e-23 83.8 0.0 2.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY81772.1 - 7.4e-12 45.2 0.0 2e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 ORY81772.1 - 1.5e-06 27.4 0.0 9.8e-06 24.7 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 ORY81772.1 - 1.5e-06 28.9 3.6 1.9e-06 28.7 3.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 ORY81772.1 - 2.9e-05 23.1 0.0 4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 ORY81772.1 - 0.0031 16.2 0.0 0.16 10.6 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 ORY81772.1 - 0.0034 17.1 0.0 0.056 13.1 0.0 2.3 1 1 0 1 1 1 1 Putative esterase Say1_Mug180 PF10340.9 ORY81772.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.5 1 1 0 1 1 1 0 Steryl acetyl hydrolase Lipase_3 PF01764.25 ORY81772.1 - 0.061 13.2 0.0 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Transp_cyt_pur PF02133.15 ORY81773.1 - 6.6e-84 282.2 36.5 9.7e-84 281.7 36.5 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MHYT PF03707.16 ORY81774.1 - 3.1e-23 81.7 12.8 1.2e-09 38.2 0.1 4.6 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat DUF1129 PF06570.11 ORY81774.1 - 1.3 8.4 5.4 3.2 7.2 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Acyltransferase PF01553.21 ORY81775.1 - 1.2e-31 109.1 0.0 1.9e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase CTP_transf_like PF01467.26 ORY81776.1 - 4.6e-26 91.7 0.0 6.3e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5405 PF17399.2 ORY81776.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5405) Bac_luciferase PF00296.20 ORY81778.1 - 4.3e-56 190.6 0.3 6.1e-56 190.1 0.3 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 ORY81779.1 - 4.8e-11 42.2 35.2 6.7e-11 41.7 35.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY81779.1 - 3.6e-07 30.0 4.5 3.6e-07 30.0 4.5 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 ORY81779.1 - 0.0021 17.0 10.5 0.0021 17.0 10.5 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Na_K-ATPase PF00287.18 ORY81780.1 - 0.075 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Shisa PF13908.6 ORY81780.1 - 0.092 13.0 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Lectin_leg-like PF03388.13 ORY81781.1 - 2.1e-09 37.1 0.0 0.012 15.0 0.0 3.9 3 1 0 3 3 3 3 Legume-like lectin family Pro-rich_19 PF15455.6 ORY81781.1 - 0.038 13.1 0.2 0.075 12.2 0.2 1.4 1 0 0 1 1 1 0 Proline-rich 19 OAD_gamma PF04277.13 ORY81782.1 - 0.21 12.2 4.5 1.3 9.7 0.0 2.9 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain FMO-like PF00743.19 ORY81783.1 - 2.4e-11 42.8 0.1 2e-10 39.7 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY81783.1 - 7.1e-09 35.8 0.0 1.7e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY81783.1 - 5.5e-08 32.4 0.0 1.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY81783.1 - 9.9e-08 31.5 0.0 3.8e-06 26.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY81783.1 - 1.2e-06 28.0 2.2 0.00012 21.5 0.9 3.8 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY81783.1 - 0.0078 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding BatD PF13584.6 ORY81783.1 - 0.042 12.7 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance Thi4 PF01946.17 ORY81783.1 - 0.055 12.7 0.1 0.15 11.3 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Proteasome PF00227.26 ORY81784.1 - 2.5e-54 183.7 0.0 3e-54 183.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY81784.1 - 3.6e-13 48.9 1.0 1.1e-12 47.4 0.1 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature UPF0113_N PF17833.1 ORY81785.1 - 6.4e-27 93.9 0.0 1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 ORY81785.1 - 1.6e-26 92.3 0.0 3.4e-26 91.3 0.0 1.5 2 0 0 2 2 2 1 UPF0113 PUA domain PP1 PF07430.11 ORY81785.1 - 0.037 14.1 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Mago-bind PF09282.10 ORY81786.1 - 4.1e-14 52.1 2.3 8.3e-14 51.1 2.3 1.6 1 0 0 1 1 1 1 Mago binding DNA_pol_phi PF04931.13 ORY81786.1 - 1 7.4 8.1 1.2 7.2 8.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi eIF3_subunit PF08597.10 ORY81786.1 - 1.3 8.9 24.3 0.032 14.2 8.3 2.1 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit PikAIV_N PF18605.1 ORY81786.1 - 2 8.1 7.0 1.6 8.4 5.0 1.9 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PDR_CDR PF06422.12 ORY81787.1 - 1.8e-11 43.8 0.0 3.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 CDR ABC transporter DUF1582 PF07621.11 ORY81787.1 - 0.74 9.8 4.9 0.5 10.3 0.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1582) FMO-like PF00743.19 ORY81788.1 - 2.8e-21 75.6 0.0 8.1e-21 74.0 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY81788.1 - 2.6e-09 36.8 0.0 3.1e-08 33.3 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY81788.1 - 1.5e-08 34.2 0.1 2.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY81788.1 - 2.3e-07 30.3 0.0 1e-06 28.2 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY81788.1 - 1.3e-05 25.2 0.3 0.00011 22.2 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY81788.1 - 0.044 14.0 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HNH_2 PF13391.6 ORY81789.1 - 3.3e-06 27.1 0.0 6.7e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease F-box-like PF12937.7 ORY81791.1 - 0.0063 16.4 0.2 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 F-box-like Cpn10 PF00166.21 ORY81792.1 - 1e-25 89.6 0.0 1.1e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Biotin_lipoyl_2 PF13533.6 ORY81792.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 Biotin-lipoyl like Cpn60_TCP1 PF00118.24 ORY81793.1 - 3.4e-89 299.7 5.9 5e-89 299.2 5.9 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SKG6 PF08693.10 ORY81794.1 - 0.047 13.1 0.2 0.18 11.2 0.2 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Opy2 PF09463.10 ORY81795.1 - 0.0086 16.4 18.9 0.013 15.8 18.9 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 ORY81795.1 - 0.25 10.8 0.6 0.56 9.7 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Chitin_synth_1 PF01644.17 ORY81796.1 - 2.8e-62 209.5 0.0 4.4e-62 208.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY81796.1 - 3.9e-24 84.4 0.0 7.3e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY81796.1 - 5.1e-23 81.5 1.7 3e-20 72.3 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY81796.1 - 1.8e-11 44.3 0.3 1.8e-11 44.3 0.3 2.3 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY81796.1 - 0.0023 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DnaJ PF00226.31 ORY81797.1 - 5.5e-19 68.1 0.7 9.8e-19 67.3 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain ABC2_membrane PF01061.24 ORY81798.1 - 1.1e-74 250.4 65.7 5.5e-42 143.6 25.8 2.9 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY81798.1 - 6.2e-39 133.6 0.1 6.9e-18 65.5 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 ORY81798.1 - 2.3e-35 120.4 1.4 2.9e-28 97.6 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 ORY81798.1 - 8.7e-14 51.9 0.1 2.5e-13 50.4 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 ORY81798.1 - 1.6e-08 35.1 0.1 4e-06 27.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY81798.1 - 5.5e-07 29.6 0.1 4.4e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ORY81798.1 - 3e-05 24.3 1.2 0.018 15.3 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ORY81798.1 - 4.8e-05 23.0 0.4 0.0007 19.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ORY81798.1 - 5.7e-05 22.8 0.3 0.09 12.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY81798.1 - 0.00026 21.0 0.2 0.44 10.6 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY81798.1 - 0.00043 20.2 0.4 0.1 12.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 ORY81798.1 - 0.00065 19.7 0.8 0.015 15.2 0.2 2.6 2 1 0 2 2 2 1 NACHT domain SMC_N PF02463.19 ORY81798.1 - 0.0018 17.7 0.1 0.078 12.4 0.0 3.0 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ORY81798.1 - 0.0027 17.4 0.1 0.68 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY81798.1 - 0.0038 17.8 0.1 2.4 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 ORY81798.1 - 0.012 15.4 0.8 3.5 7.4 0.6 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.7 ORY81798.1 - 0.012 14.7 47.7 0.011 14.9 16.5 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein dNK PF01712.19 ORY81798.1 - 0.027 14.3 0.0 0.83 9.5 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase cobW PF02492.19 ORY81798.1 - 0.027 14.0 2.9 0.13 11.9 0.8 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORY81798.1 - 0.032 14.4 0.2 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY81798.1 - 0.032 14.2 0.3 0.082 12.9 0.3 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ORY81798.1 - 0.033 13.5 0.1 2.3 7.5 0.1 2.7 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.6 ORY81798.1 - 0.035 13.8 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ORY81798.1 - 0.045 13.0 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 ORY81798.1 - 0.046 14.1 0.1 0.76 10.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 ORY81798.1 - 0.049 14.1 0.1 0.16 12.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY81798.1 - 0.065 13.2 0.2 1 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 ORY81798.1 - 0.084 12.8 0.8 8.3 6.3 0.2 3.1 3 0 0 3 3 3 0 NTPase Rad17 PF03215.15 ORY81798.1 - 0.085 12.8 0.1 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Deltameth_res PF16020.5 ORY81798.1 - 0.092 12.6 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Deltamethrin resistance Ploopntkinase3 PF18751.1 ORY81798.1 - 0.094 12.6 0.2 15 5.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 ORY81798.1 - 0.11 12.8 1.4 0.6 10.3 0.6 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY81798.1 - 0.16 11.0 0.4 5.9 5.9 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Herpes_Helicase PF02689.14 ORY81798.1 - 0.21 9.4 0.7 0.53 8.1 0.0 1.9 2 0 0 2 2 2 0 Helicase AAA PF00004.29 ORY81798.1 - 0.22 12.0 1.0 5 7.5 0.3 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORY81798.1 - 0.42 11.0 1.7 4.3 7.8 0.2 3.0 3 0 0 3 3 2 0 AAA domain ABC2_membrane_2 PF12679.7 ORY81798.1 - 0.68 9.2 26.2 0.51 9.6 7.7 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein Methyltransf_11 PF08241.12 ORY81799.1 - 5.7e-15 55.7 0.0 2e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY81799.1 - 3.9e-11 43.5 0.0 1.1e-10 42.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY81799.1 - 3.1e-08 33.6 0.0 8e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY81799.1 - 5.1e-07 30.4 0.0 9.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FMO-like PF00743.19 ORY81800.1 - 4.5e-13 48.5 0.0 9e-12 44.2 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 ORY81800.1 - 3e-10 40.2 0.0 7.2e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY81800.1 - 8.4e-09 35.1 0.0 1.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY81800.1 - 2.6e-06 26.8 0.0 6.8e-05 22.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY81800.1 - 5.6e-05 22.5 2.1 0.25 10.6 0.0 4.0 3 2 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY81800.1 - 0.00029 20.9 0.2 0.0034 17.4 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY81800.1 - 0.07 11.8 0.2 0.12 11.0 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 ORY81800.1 - 0.071 12.7 0.2 6.9 6.1 0.0 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.16 ORY81801.1 - 1.5e-36 126.1 69.3 6.9e-32 110.7 44.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Autophagy_act_C PF03987.15 ORY81802.1 - 4.1e-16 59.3 1.9 6e-16 58.8 1.9 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Acyl-CoA_dh_1 PF00441.24 ORY81803.1 - 1.4e-26 93.5 0.9 2.3e-26 92.8 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY81803.1 - 1.3e-18 66.9 0.0 2.7e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY81803.1 - 3.2e-12 46.9 0.6 5.6e-12 46.1 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY81803.1 - 7.3e-11 42.7 0.1 1.7e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain DUF2838 PF10998.8 ORY81805.1 - 8.6e-40 135.4 7.9 2e-39 134.2 7.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) DUF3784 PF12650.7 ORY81805.1 - 0.078 13.2 4.3 6.7 7.0 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) HisKA_3 PF07730.13 ORY81805.1 - 0.11 13.1 1.3 3.6 8.2 0.3 2.5 2 0 0 2 2 2 0 Histidine kinase dCache_3 PF14827.6 ORY81805.1 - 0.16 11.6 0.2 0.27 10.9 0.2 1.3 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase YtxH PF12732.7 ORY81805.1 - 2 9.0 4.4 36 5.0 0.1 2.6 2 0 0 2 2 2 0 YtxH-like protein CCDC-167 PF15188.6 ORY81805.1 - 5.8 7.3 7.3 5.1 7.5 3.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Fungal_trans PF04082.18 ORY81806.1 - 1.3e-11 44.1 0.0 2.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY81806.1 - 8.8e-07 28.9 8.3 1.4e-06 28.3 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RMF PF04957.12 ORY81806.1 - 0.12 12.6 0.1 0.38 11.0 0.1 1.8 2 0 0 2 2 2 0 Ribosome modulation factor RraA-like PF03737.15 ORY81807.1 - 1.6e-25 90.0 0.0 1.9e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA Mito_carr PF00153.27 ORY81808.1 - 6.1e-60 199.2 3.6 3.1e-19 68.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 ORY81808.1 - 0.0041 17.3 0.0 0.031 14.5 0.0 2.2 2 0 0 2 2 2 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Fuseless PF15993.5 ORY81808.1 - 0.18 11.0 0.0 0.56 9.3 0.0 1.7 1 1 0 2 2 2 0 Fuseless Dala_Dala_lig_C PF07478.13 ORY81809.1 - 5.9e-06 26.0 0.0 1.4e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.6 ORY81809.1 - 0.024 14.3 0.3 0.071 12.7 0.3 1.7 1 1 0 1 1 1 0 ATP-grasp domain Disulph_isomer PF06491.11 ORY81809.1 - 0.042 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase DUF5444 PF17519.2 ORY81809.1 - 0.23 11.5 0.4 1.7 8.7 0.1 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5444) Aconitase PF00330.20 ORY81810.1 - 1.8e-138 462.4 0.0 2.3e-138 462.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY81810.1 - 1e-40 139.1 0.0 1.7e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Amidohydro_2 PF04909.14 ORY81811.1 - 2.2e-21 76.9 0.3 1.9e-20 73.8 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase Glyco_hydro_97 PF10566.9 ORY81811.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 Sugar_tr PF00083.24 ORY81812.1 - 6.9e-95 318.5 25.1 8.1e-95 318.3 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY81812.1 - 2.7e-26 92.3 41.3 1.3e-18 67.1 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 ORY81813.1 - 2.1e-67 227.3 0.0 2.9e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY81813.1 - 1.9e-46 158.5 0.0 3.4e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 ORY81813.1 - 1.8e-16 60.3 0.0 3.4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 ORY81813.1 - 7.3e-15 54.8 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY81813.1 - 1.2e-11 44.9 0.0 2.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 ORY81813.1 - 2.1e-06 27.3 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY81813.1 - 0.0054 15.6 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SAM_4 PF18017.1 ORY81813.1 - 0.007 16.3 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FMN_red PF03358.15 ORY81815.1 - 4.6e-08 33.0 0.2 1.2e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 ORY81815.1 - 1.7e-05 25.0 0.1 0.0042 17.3 0.2 2.3 1 1 1 2 2 2 2 Flavodoxin domain Flavodoxin_1 PF00258.25 ORY81815.1 - 0.00037 20.7 0.1 0.0034 17.6 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin FAD_binding_3 PF01494.19 ORY81816.1 - 1.2e-67 228.7 0.1 1.1e-66 225.4 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORY81816.1 - 7.1e-27 94.5 0.0 1.6e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 ORY81816.1 - 0.0002 20.2 0.0 0.0003 19.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ORY81816.1 - 0.0005 19.4 0.0 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY81816.1 - 0.001 18.2 0.2 0.002 17.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY81816.1 - 0.0028 17.8 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY81816.1 - 0.03 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 ORY81816.1 - 0.036 13.1 0.1 0.059 12.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 ORY81816.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 ORY81816.1 - 0.083 12.4 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY81816.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_S3Ae PF01015.18 ORY81817.1 - 2.1e-90 301.7 3.3 2.5e-90 301.5 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 ORY81817.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ribosomal_L17 PF01196.19 ORY81817.1 - 0.1 13.5 0.3 0.21 12.5 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L17 AC_N PF16214.5 ORY81817.1 - 0.14 11.2 0.3 0.93 8.6 0.1 1.9 1 1 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Ribosomal_S3Ae PF01015.18 ORY81819.1 - 2.2e-70 236.4 2.9 2.5e-70 236.2 2.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 ORY81819.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region SUI1 PF01253.22 ORY81819.1 - 0.06 13.9 0.4 4.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Translation initiation factor SUI1 Ribosomal_L17 PF01196.19 ORY81819.1 - 0.07 14.0 0.3 0.12 13.2 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L17 QRPTase_C PF01729.19 ORY81821.1 - 4e-52 176.4 0.1 5.7e-52 175.9 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ORY81821.1 - 1e-17 63.9 0.0 4.4e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain TMP-TENI PF02581.17 ORY81821.1 - 0.017 14.5 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase LysR_substrate PF03466.20 ORY81821.1 - 0.15 11.4 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Adaptin_binding PF10199.9 ORY81822.1 - 2.4e-11 44.3 0.0 4.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 LRR_4 PF12799.7 ORY81823.1 - 0.1 13.0 4.6 6.9 7.2 0.0 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) DUF1640 PF07798.11 ORY81824.1 - 1.1e-29 103.8 8.2 1.1e-29 103.7 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Troponin PF00992.20 ORY81824.1 - 0.002 18.4 0.7 0.0034 17.7 0.7 1.4 1 0 0 1 1 1 1 Troponin Prominin PF05478.11 ORY81824.1 - 0.085 10.8 3.5 0.09 10.7 3.5 1.0 1 0 0 1 1 1 0 Prominin Ferlin_C PF16165.5 ORY81824.1 - 0.1 12.6 0.4 0.15 12.0 0.4 1.3 1 0 0 1 1 1 0 Ferlin C-terminus PC-Esterase PF13839.6 ORY81825.1 - 2.6e-11 43.8 4.1 6.1e-11 42.6 4.1 1.6 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Iso_dh PF00180.20 ORY81826.1 - 7.6e-88 295.0 0.0 1.2e-87 294.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase F-box PF00646.33 ORY81828.1 - 0.0016 18.2 0.1 0.0056 16.5 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY81828.1 - 0.0037 17.1 0.1 0.0093 15.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like BOP1NT PF08145.12 ORY81831.1 - 3e-100 335.4 1.8 4.7e-100 334.8 1.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 ORY81831.1 - 8.4e-19 67.6 1.4 0.00021 22.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY81831.1 - 0.0051 17.1 0.0 1.8 8.9 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Slx4 PF09494.10 ORY81833.1 - 0.047 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Slx4 endonuclease PRiA4_ORF3 PF07929.11 ORY81834.1 - 2.3e-20 73.0 0.0 4.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.18 ORY81834.1 - 2.4e-12 46.7 10.5 4e-12 46.0 10.5 1.4 1 0 0 1 1 1 1 MYND finger LRR_8 PF13855.6 ORY81835.1 - 2.2 8.1 5.1 10 6.0 0.0 3.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 ORY81835.1 - 3.7 7.8 5.1 21 5.5 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 ORY81836.1 - 0.0036 17.0 2.0 21 5.0 0.1 4.6 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY81836.1 - 0.0074 16.7 7.3 9.3 6.8 0.3 5.4 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) Ras PF00071.22 ORY81837.1 - 2.8e-39 134.3 0.0 3.8e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY81837.1 - 1.2e-10 41.7 0.0 4.3e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY81837.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Mem_trans PF03547.18 ORY81838.1 - 1.2e-13 50.2 0.0 3.9e-13 48.6 0.0 1.7 1 1 0 1 1 1 1 Membrane transport protein CDC37_N PF03234.14 ORY81839.1 - 1.1e-37 129.9 0.6 1.1e-37 129.9 0.6 3.1 3 0 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 ORY81839.1 - 1.7e-25 89.2 0.4 8.8e-25 86.9 0.0 2.1 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 ORY81839.1 - 7.8e-21 74.1 2.6 1.1e-20 73.6 0.1 2.4 2 0 0 2 2 2 1 Cdc37 C terminal domain CtsR_C PF17727.1 ORY81839.1 - 0.022 14.9 0.2 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain HTH_22 PF13309.6 ORY81839.1 - 0.039 14.0 0.1 0.1 12.7 0.1 1.7 1 0 0 1 1 1 0 HTH domain DUF4844 PF16133.5 ORY81839.1 - 0.12 12.9 0.9 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) LIM PF00412.22 ORY81840.1 - 1.3e-21 76.6 22.5 3.7e-09 36.7 0.3 4.4 2 1 2 4 4 4 3 LIM domain DUF1326 PF07040.11 ORY81841.1 - 0.55 10.2 6.5 0.75 9.8 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) Myotub-related PF06602.14 ORY81842.1 - 1.3e-133 445.3 0.0 1.6e-133 445.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 ORY81842.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Death PF00531.22 ORY81843.1 - 0.13 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Death domain RCDG1 PF15725.5 ORY81844.1 - 1 9.8 4.6 1.9 9.0 4.6 1.4 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein COesterase PF00135.28 ORY81845.1 - 1.5e-78 265.0 0.0 1.9e-78 264.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY81845.1 - 9e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY81845.1 - 0.0078 15.9 0.0 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY81845.1 - 0.027 14.0 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY81845.1 - 0.098 11.9 0.0 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Spherulin4 PF12138.8 ORY81846.1 - 8.5e-16 58.3 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 Spherulin4 PF12138.8 ORY81847.1 - 1.1e-82 277.4 1.4 5.8e-41 140.7 0.0 2.0 2 0 0 2 2 2 2 Spherulation-specific family 4 Spherulin4 PF12138.8 ORY81848.1 - 2.9e-41 141.7 0.0 5.4e-40 137.5 0.0 2.2 1 1 0 1 1 1 1 Spherulation-specific family 4 JAB PF01398.21 ORY81849.1 - 1.4e-16 60.6 0.0 2.2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 ORY81849.1 - 4e-06 26.6 1.5 5.2e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain FlbD PF06289.11 ORY81849.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins TPR_1 PF00515.28 ORY81850.1 - 2.1e-10 40.0 5.2 7.7e-05 22.3 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY81850.1 - 4.6e-06 26.2 3.5 6.6e-05 22.5 1.3 3.6 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 ORY81850.1 - 5.9e-06 26.8 2.3 8.4e-06 26.3 0.5 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY81850.1 - 3.1e-05 23.7 10.2 0.02 15.0 0.3 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY81850.1 - 0.0011 19.4 0.3 0.0031 18.0 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY81850.1 - 0.0023 17.9 0.6 5.6 7.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY81850.1 - 0.038 14.2 3.9 0.39 11.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY81850.1 - 0.077 13.3 2.7 0.18 12.1 0.8 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY81850.1 - 0.095 13.1 1.2 0.74 10.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY81850.1 - 0.69 10.9 5.4 13 6.9 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat Spo12 PF05032.12 ORY81851.1 - 1.2e-10 41.1 4.0 3e-10 39.8 4.0 1.7 1 0 0 1 1 1 1 Spo12 family MGC-24 PF05283.11 ORY81852.1 - 0.015 15.7 0.7 0.032 14.7 0.7 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Herpes_gE PF02480.16 ORY81852.1 - 0.03 13.1 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4805 PF16063.5 ORY81852.1 - 0.047 13.0 1.5 0.07 12.4 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) DUF3446 PF11928.8 ORY81852.1 - 2.4 8.5 11.8 0.43 10.9 7.6 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain Ribosomal_60s PF00428.19 ORY81852.1 - 6.5 7.4 10.2 5.9 7.6 5.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.22 ORY81854.1 - 9.1e-20 70.3 0.0 2.9e-06 27.0 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 ORY81854.1 - 2.9 7.0 8.5 6.4 5.8 1.5 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein TPR_1 PF00515.28 ORY81855.1 - 9.3e-23 79.1 9.0 0.0004 20.1 0.0 11.2 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY81855.1 - 2e-22 77.5 29.5 7.2e-05 22.6 0.0 12.7 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY81855.1 - 1.1e-21 75.1 2.8 0.011 15.9 0.0 11.1 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY81855.1 - 6.6e-19 68.3 55.1 1.9e-05 25.2 0.0 13.9 13 2 2 15 15 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORY81855.1 - 1.3e-15 56.7 51.5 0.0014 19.3 0.0 16.3 13 3 6 19 19 16 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY81855.1 - 4e-14 51.9 2.6 4.1 8.0 0.0 11.9 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY81855.1 - 7.9e-14 51.7 34.2 0.039 14.2 1.2 11.9 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY81855.1 - 1.7e-10 41.2 32.6 0.056 14.0 0.0 12.1 11 2 3 15 15 14 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY81855.1 - 6.4e-09 35.4 7.6 0.0074 16.0 0.0 7.9 7 1 1 8 8 8 2 TPR repeat TPR_6 PF13174.6 ORY81855.1 - 1.4e-08 34.8 21.5 7 7.5 0.0 11.7 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY81855.1 - 1.5e-07 31.4 21.4 0.022 14.9 0.0 9.0 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY81855.1 - 1.6e-07 30.9 11.7 2 8.6 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY81855.1 - 0.00028 21.0 5.9 0.61 10.3 0.0 6.6 7 1 1 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORY81855.1 - 0.012 15.4 19.3 2.5 8.1 0.1 7.9 7 0 0 7 7 7 0 Tetratricopeptide repeat FAT PF02259.23 ORY81855.1 - 0.022 14.0 0.1 23 4.1 0.0 3.4 3 0 0 3 3 3 0 FAT domain LRR_4 PF12799.7 ORY81856.1 - 3.8e-06 27.2 5.0 1.7 9.2 0.0 5.2 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY81856.1 - 0.022 15.3 8.1 17 6.4 0.0 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY81856.1 - 0.056 13.2 7.7 3.8 7.3 0.1 4.5 4 1 1 5 5 5 0 Leucine rich repeat OrsD PF12013.8 ORY81858.1 - 0.00021 21.7 0.2 0.00021 21.7 0.2 2.3 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D GATA PF00320.27 ORY81858.1 - 0.033 13.8 2.3 5.1 6.8 0.1 2.5 2 0 0 2 2 2 0 GATA zinc finger TCL1_MTCP1 PF01840.17 ORY81858.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 TCL1/MTCP1 family Ribosomal_L9_N PF01281.19 ORY82305.1 - 1.1e-11 44.1 0.0 2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 ORY82305.1 - 4.9e-05 23.7 0.2 0.00014 22.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain E_Pc_C PF06752.12 ORY82305.1 - 0.054 13.6 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus HIM1 PF08732.10 ORY82306.1 - 0.069 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 HIM1 Stig1 PF04885.13 ORY82307.1 - 0.029 14.8 79.5 0.28 11.7 3.2 7.7 3 1 3 6 6 6 0 Stigma-specific protein, Stig1 RabGAP-TBC PF00566.18 ORY82308.1 - 5.6e-32 111.1 0.0 7.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pet100 PF09803.9 ORY82308.1 - 0.46 11.1 2.3 1.2 9.7 2.3 1.7 1 0 0 1 1 1 0 Pet100 Exo_endo_phos PF03372.23 ORY82309.1 - 2.7e-17 63.1 0.0 1.4e-16 60.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family F-box-like PF12937.7 ORY82312.1 - 0.053 13.4 0.1 0.17 11.8 0.1 2.0 1 0 0 1 1 1 0 F-box-like DUF1772 PF08592.11 ORY82313.1 - 0.027 14.8 0.4 0.027 14.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) TPP_enzyme_N PF02776.18 ORY82314.1 - 2e-31 108.9 0.3 3.4e-31 108.2 0.3 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY82314.1 - 2.7e-17 62.8 0.0 8e-17 61.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 ORY82314.1 - 2.2e-12 47.0 0.1 1.8e-11 44.0 0.0 2.5 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glycos_transf_2 PF00535.26 ORY82314.1 - 0.044 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 AMH_N PF04709.12 ORY82315.1 - 0.17 10.7 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region Myosin_head PF00063.21 ORY82318.1 - 1.4e-237 790.3 0.0 1.7e-237 790.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 ORY82318.1 - 1.6e-54 184.4 0.0 2.6e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 ORY82318.1 - 4e-09 36.2 0.1 1.2e-08 34.7 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY82318.1 - 3.4e-08 33.0 0.2 7.2e-08 31.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY82318.1 - 5.1e-08 32.5 0.1 2.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Hpr_kinase_C PF07475.12 ORY82318.1 - 0.014 14.9 1.7 7.1 6.1 0.1 3.3 4 0 0 4 4 4 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 ORY82318.1 - 0.051 14.0 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORY82318.1 - 0.055 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY82318.1 - 0.18 11.7 0.1 0.39 10.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain IQ PF00612.27 ORY82318.1 - 2 8.4 4.9 17 5.5 0.2 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif IBR PF01485.21 ORY82319.1 - 1e-05 25.7 3.4 1e-05 25.7 3.4 2.6 3 1 0 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 ORY82319.1 - 0.00084 19.3 3.7 0.00084 19.3 3.7 2.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY82319.1 - 0.0028 17.5 1.4 0.0028 17.5 1.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY82319.1 - 0.0049 17.2 3.8 0.0049 17.2 3.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY82319.1 - 0.0049 16.9 6.3 0.0049 16.9 6.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY82319.1 - 0.013 15.4 2.4 0.013 15.4 2.4 2.9 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY82319.1 - 0.041 13.8 2.0 0.041 13.8 2.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY82319.1 - 0.7 10.1 14.1 0.27 11.4 6.5 3.3 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING F-box-like PF12937.7 ORY82320.1 - 6.4e-06 26.0 0.1 1.4e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY82320.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box_5 PF18511.1 ORY82320.1 - 0.12 12.0 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 F-box DEAD PF00270.29 ORY82321.1 - 1.9e-42 145.0 0.0 8.3e-42 142.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY82321.1 - 3.2e-27 95.1 0.1 3e-26 92.0 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY82321.1 - 0.00021 21.4 0.0 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 ORY82321.1 - 0.00097 19.1 1.0 0.0017 18.3 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 ORY82321.1 - 0.0061 16.3 0.9 0.014 15.2 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle SecA_DEAD PF07517.14 ORY82321.1 - 0.049 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain VIR_N PF15912.5 ORY82321.1 - 0.16 11.5 4.1 0.26 10.8 4.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal zf-CCHC_6 PF15288.6 ORY82321.1 - 0.19 11.6 0.8 0.47 10.3 0.8 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF4604 PF15377.6 ORY82321.1 - 1.1 9.7 12.9 4.3 7.7 13.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF2570 PF10828.8 ORY82321.1 - 1.4 8.8 7.7 3.3 7.6 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) FLILHELTA PF10306.9 ORY82322.1 - 1.1e-13 51.3 0.0 2.5e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 ORY82322.1 - 0.13 12.8 0.3 0.32 11.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) DUF4519 PF15012.6 ORY82322.1 - 2.2 8.5 4.6 0.64 10.2 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) IBR PF01485.21 ORY82324.1 - 2.3e-08 34.1 27.1 7.9e-06 26.0 2.6 3.4 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 ORY82324.1 - 0.0011 18.9 3.8 0.0011 18.9 3.8 4.1 3 2 2 5 5 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY82324.1 - 0.0027 17.5 1.8 0.0027 17.5 1.8 4.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY82324.1 - 0.0047 16.9 5.6 0.0047 16.9 5.6 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY82324.1 - 0.031 14.6 4.2 0.031 14.6 4.2 4.0 2 1 1 3 3 3 0 Ring finger domain TMEM154 PF15102.6 ORY82326.1 - 0.063 13.2 0.1 0.063 13.2 0.1 2.5 1 1 1 2 2 2 0 TMEM154 protein family RIFIN PF02009.16 ORY82326.1 - 1.4 8.7 2.8 2.3 8.0 2.8 1.2 1 0 0 1 1 1 0 Rifin RRM_1 PF00076.22 ORY82327.1 - 2.5e-13 49.7 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 ORY82327.1 - 0.012 15.5 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 RL domain Nup35_RRM_2 PF14605.6 ORY82327.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY82327.1 - 0.071 13.2 0.0 0.22 11.7 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif PRMT5_TIM PF17285.2 ORY82328.1 - 5.6e-76 255.1 0.0 8.3e-76 254.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 ORY82328.1 - 7.7e-61 204.9 0.0 1.1e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 ORY82328.1 - 7.2e-53 179.1 0.0 9.8e-53 178.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 ORY82328.1 - 0.0032 18.1 0.0 0.0076 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ORY82328.1 - 0.0039 17.0 0.0 0.0061 16.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Fungal_trans PF04082.18 ORY82329.1 - 1.4e-15 57.0 0.0 2.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY82329.1 - 2.1e-10 40.5 6.8 4.2e-10 39.6 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oest_recep PF02159.15 ORY82329.1 - 0.75 10.3 3.9 2.2 8.8 3.9 1.7 1 0 0 1 1 1 0 Oestrogen receptor PsbN PF02468.15 ORY82330.1 - 0.4 10.6 2.4 2.1 8.3 0.1 2.9 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) His_Phos_1 PF00300.22 ORY82331.1 - 1.4e-11 44.5 0.0 5.4e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Torus PF16131.5 ORY82332.1 - 4.4e-38 130.3 0.1 8.2e-38 129.5 0.1 1.4 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 ORY82332.1 - 8.7e-10 38.3 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY82332.1 - 6.8e-05 22.8 0.1 0.00014 21.8 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 ORY82332.1 - 0.0045 16.7 6.9 0.0076 16.0 6.9 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 ORY82332.1 - 0.1 12.6 7.7 0.18 11.7 7.7 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY82332.1 - 0.13 12.3 6.6 0.22 11.6 6.6 1.3 1 0 0 1 1 1 0 Zinc finger domain RRM_5 PF13893.6 ORY82332.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP_N PF01213.19 ORY82332.1 - 4 6.8 7.9 9.4 5.6 7.9 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NDUF_B8 PF05821.11 ORY82333.1 - 0.0068 16.3 0.3 0.01 15.7 0.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Lyase_1 PF00206.20 ORY82334.1 - 1.7e-21 77.0 0.0 2.4e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORY82334.1 - 6.7e-19 68.2 0.0 2.1e-18 66.6 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DIOX_N PF14226.6 ORY82335.1 - 3.4e-06 27.8 0.0 6.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY82335.1 - 0.00068 20.1 0.0 0.0012 19.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 ORY82336.1 - 4.1e-94 316.0 24.1 4.9e-94 315.7 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY82336.1 - 1.8e-28 99.5 40.3 2.3e-28 99.1 25.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY82336.1 - 1.1e-07 30.7 1.7 1.1e-07 30.7 1.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 ORY82336.1 - 0.044 14.3 6.8 0.057 14.0 3.2 2.9 2 1 0 2 2 2 0 Phage holin family 2 Sugar_tr PF00083.24 ORY82339.1 - 5.8e-100 335.3 25.8 7e-100 335.0 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY82339.1 - 7.7e-30 104.0 41.6 1.8e-29 102.8 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY82339.1 - 4.5e-08 32.0 1.6 1.2e-07 30.6 1.6 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_3_2 PF04550.12 ORY82339.1 - 0.06 13.9 6.8 0.07 13.7 3.2 2.8 2 1 0 2 2 2 0 Phage holin family 2 Sugar_tr PF00083.24 ORY82340.1 - 3.6e-72 243.7 15.7 5.6e-72 243.0 15.7 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY82340.1 - 3.1e-17 62.5 40.5 4.7e-13 48.8 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 ORY82340.1 - 0.66 10.6 9.7 1.3 9.6 3.8 2.9 2 0 0 2 2 2 0 Phage holin family 2 Sulfate_transp PF00916.20 ORY82341.1 - 4.3e-114 381.2 17.5 5.3e-114 380.9 17.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY82341.1 - 5.7e-07 29.2 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY82341.1 - 0.0027 18.1 12.5 0.03 14.7 1.6 2.9 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORY82341.1 - 0.013 15.8 0.1 0.046 14.1 0.0 1.9 2 0 0 2 2 2 0 STAS domain His_biosynth PF00977.21 ORY82343.1 - 1.4e-34 119.6 0.0 1.7e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein CAF1C_H4-bd PF12265.8 ORY82344.1 - 4e-27 94.3 0.3 1.3e-26 92.6 0.4 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 ORY82344.1 - 1.4e-26 92.2 0.3 8.4e-05 23.3 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY82344.1 - 2.9e-05 24.3 0.4 0.048 14.0 0.1 4.4 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY82344.1 - 0.0042 17.0 0.2 0.028 14.3 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A F-box-like PF12937.7 ORY82345.1 - 0.00099 19.0 0.1 0.0029 17.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like RPN7 PF10602.9 ORY82347.1 - 1.7e-43 148.4 0.0 3.1e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORY82347.1 - 3.9e-13 49.8 0.0 1e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 ORY82347.1 - 0.011 15.7 0.1 0.45 10.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat INT_SG_DDX_CT_C PF15300.6 ORY82347.1 - 0.055 13.3 1.3 0.56 10.1 0.7 2.4 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Sulfotransfer_4 PF17784.1 ORY82348.1 - 3.2e-58 197.1 0.0 3.7e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Spore_YabQ PF09578.10 ORY82348.1 - 0.069 13.4 0.2 2.9 8.2 0.2 2.3 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) Pil1 PF13805.6 ORY82349.1 - 2.2e-34 119.1 2.8 3.5e-34 118.5 2.8 1.3 1 0 0 1 1 1 1 Eisosome component PIL1 Snapin_Pallidin PF14712.6 ORY82349.1 - 0.00084 19.7 4.4 0.0026 18.1 4.4 1.7 1 0 0 1 1 1 1 Snapin/Pallidin Gp-FAR-1 PF05823.12 ORY82349.1 - 0.16 12.4 2.5 0.32 11.4 2.5 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) UPF0242 PF06785.11 ORY82349.1 - 4.2 7.4 14.0 0.2 11.8 5.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Pyr_redox_2 PF07992.14 ORY82350.1 - 2.8e-56 190.9 0.0 3.4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY82350.1 - 1.3e-11 44.9 0.3 1.8e-09 38.0 0.0 3.0 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY82350.1 - 0.0019 17.6 0.0 0.42 9.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase S1 PF00575.23 ORY82350.1 - 0.029 14.7 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 S1 RNA binding domain DsrC PF04358.13 ORY82350.1 - 0.12 12.9 0.1 0.41 11.2 0.0 1.9 2 0 0 2 2 2 0 DsrC like protein NAD_binding_9 PF13454.6 ORY82350.1 - 0.19 11.7 0.6 28 4.7 0.2 3.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY82350.1 - 0.29 9.8 0.4 0.86 8.2 0.0 1.8 1 1 1 2 2 2 0 HI0933-like protein Abhydrolase_3 PF07859.13 ORY82351.1 - 1.2e-31 110.2 0.0 1.6e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY82351.1 - 3.8e-09 35.9 0.0 5.3e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 ORY82351.1 - 7.7e-06 26.7 1.0 7.7e-06 26.7 1.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 ORY82351.1 - 0.07 12.7 0.0 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ORY82351.1 - 0.19 11.2 0.0 9.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Importin_rep_4 PF18808.1 ORY82352.1 - 1.6e-21 76.4 2.1 2.4e-21 75.8 0.3 2.4 2 0 0 2 2 2 1 Importin repeat HEAT PF02985.22 ORY82352.1 - 6e-16 57.2 8.4 0.00015 21.8 0.0 8.2 8 0 0 8 8 7 4 HEAT repeat HEAT_EZ PF13513.6 ORY82352.1 - 1.8e-11 44.3 22.7 7.3e-06 26.4 0.1 9.5 10 2 2 12 12 10 4 HEAT-like repeat HEAT_2 PF13646.6 ORY82352.1 - 8.7e-11 42.1 16.9 0.00019 21.7 0.1 6.3 3 2 3 6 6 6 4 HEAT repeats IFRD PF05004.13 ORY82352.1 - 1.4e-08 34.2 0.9 0.6 9.2 0.0 5.7 4 2 1 5 5 5 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 ORY82352.1 - 3.8e-07 30.6 1.6 0.0055 17.3 0.1 5.6 5 1 1 6 6 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY82352.1 - 1.5e-06 28.3 0.0 0.15 12.1 0.0 4.2 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 ORY82352.1 - 6.6e-05 22.2 4.0 0.19 10.8 2.0 4.4 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 ORY82352.1 - 0.00013 20.7 0.1 0.21 10.1 0.0 3.7 2 1 2 4 4 4 1 Adaptin N terminal region DUF4042 PF13251.6 ORY82352.1 - 0.00087 19.0 0.1 3.6 7.3 0.0 3.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) V-ATPase_H_N PF03224.14 ORY82352.1 - 0.0077 15.6 0.0 7.3 5.8 0.0 3.0 2 1 1 3 3 3 2 V-ATPase subunit H INTS5_N PF14837.6 ORY82352.1 - 0.072 12.7 0.0 0.39 10.3 0.0 2.2 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus YdaT_toxin PF06254.11 ORY82352.1 - 0.099 13.2 0.2 0.75 10.4 0.1 2.5 2 0 0 2 2 2 0 Putative bacterial toxin ydaT HEAT_PBS PF03130.16 ORY82352.1 - 0.36 11.6 0.1 0.36 11.6 0.1 5.5 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat PAPS_reduct PF01507.19 ORY82353.1 - 1.1e-22 80.9 0.0 1.3e-21 77.4 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3012 PF11216.8 ORY82353.1 - 0.15 12.1 0.4 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Methyltransf_31 PF13847.6 ORY82354.1 - 2.4e-29 102.1 0.0 3.1e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY82354.1 - 5.2e-22 78.4 0.0 1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY82354.1 - 3.2e-21 75.8 0.0 5.8e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY82354.1 - 5.7e-17 62.0 0.0 9.5e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY82354.1 - 4.5e-16 59.4 0.0 7.5e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY82354.1 - 1.3e-13 50.9 0.0 1.9e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 ORY82354.1 - 1.3e-08 34.2 0.0 1.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 ORY82354.1 - 2.9e-06 26.9 0.0 7.4e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 ORY82354.1 - 5.9e-06 26.2 0.0 7.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORY82354.1 - 1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 ORY82354.1 - 1.1e-05 25.1 0.0 2.4e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 ORY82354.1 - 3.7e-05 23.1 0.0 5.9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 ORY82354.1 - 0.00067 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_24 PF13578.6 ORY82354.1 - 0.004 18.1 0.1 0.014 16.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 ORY82354.1 - 0.0081 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.16 ORY82354.1 - 0.0083 14.7 0.0 0.012 14.1 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_PK PF05891.12 ORY82354.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_32 PF13679.6 ORY82354.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 ORY82354.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Abhydrolase_3 PF07859.13 ORY82355.1 - 5.3e-34 117.9 0.1 8.3e-25 87.9 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY82355.1 - 8.9e-08 31.4 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase UreE_C PF05194.12 ORY82355.1 - 0.19 12.3 7.6 0.54 10.8 7.6 1.8 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain SPX PF03105.19 ORY82355.1 - 0.22 11.4 5.4 0.33 10.8 5.4 1.3 1 0 0 1 1 1 0 SPX domain SelP_N PF04592.14 ORY82355.1 - 0.82 9.0 8.3 1.4 8.3 8.3 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region GREB1 PF15782.5 ORY82355.1 - 1.1 6.3 3.0 1.6 5.8 3.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 ORY82355.1 - 2.8 6.4 4.3 3.4 6.1 4.3 1.1 1 0 0 1 1 1 0 Macoilin family AA_permease PF00324.21 ORY82356.1 - 4.7 5.7 8.5 1.6 7.3 5.5 1.7 2 1 0 2 2 2 0 Amino acid permease DSPc PF00782.20 ORY82357.1 - 1.9e-33 115.1 0.0 2.2e-24 85.8 0.0 3.0 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY82357.1 - 0.004 16.7 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Sulfotransfer_4 PF17784.1 ORY82358.1 - 2.1e-62 210.8 0.1 2.4e-62 210.6 0.1 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY82358.1 - 0.0053 17.2 0.0 0.85 10.0 0.0 2.4 2 1 0 2 2 2 2 Sulfotransferase family MFS_1 PF07690.16 ORY82359.1 - 5.4e-29 101.2 24.9 8.1e-29 100.6 24.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3938 PF13074.6 ORY82359.1 - 8 6.8 7.6 23 5.3 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3938) ApbA PF02558.16 ORY82360.1 - 8.7e-30 103.4 0.2 1.3e-29 102.8 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 ORY82360.1 - 6.2e-26 91.0 0.0 1.1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.6 ORY82360.1 - 0.0045 17.4 0.0 0.0093 16.4 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Octopine_DH PF02317.17 ORY82360.1 - 0.036 14.1 0.5 0.5 10.5 0.5 2.2 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain MFS_1 PF07690.16 ORY82361.1 - 3.8e-30 105.0 34.9 6.8e-30 104.2 34.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PRD1_DD PF11087.8 ORY82361.1 - 0.68 9.7 6.2 4.4 7.1 0.0 4.3 4 0 0 4 4 4 0 PRD1 phage membrane DNA delivery PX PF00787.24 ORY82363.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 PX domain Adaptin_N PF01602.20 ORY82365.1 - 2e-97 327.0 4.1 3e-97 326.4 4.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 ORY82365.1 - 5.9e-61 204.5 0.2 1.1e-60 203.6 0.2 1.5 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 ORY82365.1 - 7.2e-58 194.1 0.0 1.9e-57 192.8 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 ORY82365.1 - 1.8e-10 41.1 0.1 0.0084 16.5 0.0 5.4 2 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.7 ORY82365.1 - 4.6e-10 39.8 3.1 7.1e-05 22.9 0.1 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY82365.1 - 8.3e-07 28.7 0.3 0.51 10.7 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Arm_2 PF04826.13 ORY82365.1 - 0.00017 21.2 0.5 0.094 12.2 0.0 2.7 1 1 1 2 2 2 2 Armadillo-like DUF5578 PF17741.1 ORY82365.1 - 0.00055 19.4 5.1 0.019 14.4 1.4 2.7 1 1 1 2 2 2 2 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 ORY82365.1 - 0.011 16.2 0.5 27 5.4 0.1 4.9 5 1 1 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 ORY82365.1 - 0.021 14.4 3.4 2.2 7.8 0.4 3.7 2 2 1 4 4 4 0 CLASP N terminal ParcG PF10274.9 ORY82365.1 - 0.049 13.8 0.6 8 6.5 0.0 2.9 2 1 0 2 2 2 0 Parkin co-regulated protein DUF421 PF04239.12 ORY82366.1 - 6.6e-10 38.7 0.0 9.1e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF421) DUF4886 PF16227.5 ORY82368.1 - 0.055 12.6 0.1 0.082 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4886) F-box-like PF12937.7 ORY82369.1 - 0.0007 19.4 0.4 0.0017 18.2 0.0 1.8 2 0 0 2 2 2 1 F-box-like DUF2526 PF10735.9 ORY82369.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Mtr2 PF10429.9 ORY82370.1 - 1.9e-08 34.4 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 VASt PF16016.5 ORY82371.1 - 4.1e-40 137.7 0.1 1.2e-39 136.2 0.0 1.7 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 ORY82371.1 - 5.7e-24 84.2 0.0 9.5e-24 83.5 0.0 1.4 1 0 0 1 1 1 1 GRAM domain TetR_C_6 PF13977.6 ORY82371.1 - 0.31 11.3 2.0 1 9.6 0.3 2.4 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Nop10p PF04135.12 ORY82372.1 - 3.1e-18 65.5 0.2 3.6e-18 65.3 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Pyridox_oxase_2 PF12766.7 ORY82373.1 - 1.1e-15 58.1 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TetR_C_24 PF17932.1 ORY82374.1 - 0.058 13.6 0.5 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Mog1 PF04603.12 ORY82374.1 - 0.18 12.2 0.1 0.34 11.3 0.1 1.4 1 0 0 1 1 1 0 Ran-interacting Mog1 protein Cdc6_C PF09079.11 ORY82374.1 - 0.65 10.0 0.0 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain DUF4400 PF14348.6 ORY82376.1 - 0.15 11.5 5.1 2.5 7.6 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) DUF2070 PF09843.9 ORY82376.1 - 1.5 7.0 4.7 2.2 6.4 4.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lactamase_B_2 PF12706.7 ORY82377.1 - 1.4e-36 125.9 1.7 2e-36 125.4 1.7 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY82377.1 - 1.1e-11 44.9 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY82377.1 - 0.022 14.8 0.4 0.12 12.3 0.3 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Pyrophosphatase PF00719.19 ORY82378.1 - 3.8e-59 199.1 0.1 4.8e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sin3a_C PF16879.5 ORY82379.1 - 4.8e-75 252.9 0.3 1.3e-73 248.3 0.0 2.7 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY82379.1 - 7.2e-46 154.1 3.6 1.2e-18 67.0 0.4 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY82379.1 - 6.2e-39 132.0 0.1 1.5e-38 130.8 0.1 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor DUF2976 PF11190.8 ORY82379.1 - 0.13 12.0 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) XendoU PF09412.10 ORY82379.1 - 0.21 10.8 0.2 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Endoribonuclease XendoU DDHD PF02862.17 ORY82379.1 - 1.1 9.4 3.6 1.6 8.8 2.0 2.1 2 0 0 2 2 2 0 DDHD domain Borrelia_P83 PF05262.11 ORY82379.1 - 7.2 5.0 10.6 0.036 12.6 1.2 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein HLH PF00010.26 ORY82381.1 - 1.1e-11 44.5 0.1 1.5e-11 44.1 0.1 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_hydro_38N PF01074.22 ORY82383.1 - 1.4e-70 238.0 0.2 2.2e-70 237.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ORY82383.1 - 1.3e-53 182.2 0.0 2.1e-53 181.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ORY82383.1 - 1.5e-24 86.0 0.0 2.9e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ORY82383.1 - 2.5e-10 40.3 0.0 5.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 ORY82383.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NCKAP5 PF15246.6 ORY82384.1 - 0.036 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein EAP30 PF04157.16 ORY82385.1 - 6e-61 205.7 0.0 6.8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Pkinase PF00069.25 ORY82386.1 - 5e-17 62.1 0.0 8.9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 ORY82386.1 - 1.2e-16 60.8 2.3 5.8e-07 30.1 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 ORY82386.1 - 4.5e-08 32.7 0.0 1e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 ORY82386.1 - 3e-06 27.0 0.9 0.026 14.7 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 ORY82386.1 - 2.5e-05 24.6 1.3 0.016 15.5 0.2 3.3 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 ORY82386.1 - 0.00031 20.8 0.8 1.6 8.7 0.0 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY82386.1 - 0.13 12.8 1.0 1.7 9.2 0.1 2.7 2 0 0 2 2 2 0 HEAT-like repeat DJ-1_PfpI PF01965.24 ORY82388.1 - 6e-43 146.5 0.0 8.8e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 ORY82388.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 ORY82388.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 ORY82388.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like SNO PF01174.19 ORY82388.1 - 0.21 11.4 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Alpha_GJ PF03229.13 ORY82390.1 - 0.41 11.2 28.1 0.87 10.1 12.1 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J SPX PF03105.19 ORY82391.1 - 8.8 6.1 8.7 9.7 6.0 8.7 1.1 1 0 0 1 1 1 0 SPX domain DUF1631 PF07793.11 ORY82391.1 - 9.6 4.5 8.0 11 4.3 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Atu4866 PF11512.8 ORY82393.1 - 0.069 13.5 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 RRM_1 PF00076.22 ORY82394.1 - 6.2e-14 51.6 0.0 1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY82394.1 - 0.0003 20.6 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF5538 PF17692.1 ORY82397.1 - 0.63 10.1 3.0 1.2 9.2 3.1 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5538) bZIP_2 PF07716.15 ORY82399.1 - 1.1e-12 47.8 10.2 1.1e-12 47.8 10.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper DUF2353 PF09789.9 ORY82399.1 - 0.043 13.2 0.4 0.057 12.8 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) bZIP_Maf PF03131.17 ORY82399.1 - 0.05 14.1 3.2 0.13 12.8 3.2 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4988 PF16378.5 ORY82399.1 - 0.16 11.7 0.0 0.85 9.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function Herpes_BLLF1 PF05109.13 ORY82399.1 - 1.3 6.9 10.2 1.6 6.6 10.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) bZIP_1 PF00170.21 ORY82399.1 - 3.3 7.9 17.3 0.054 13.6 8.7 2.2 2 1 0 2 2 2 0 bZIP transcription factor ThiF PF00899.21 ORY82400.1 - 1e-63 215.0 0.0 1.4e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 ORY82400.1 - 4.7e-28 97.2 0.2 8.1e-28 96.4 0.2 1.4 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 ORY82400.1 - 5.4e-06 26.9 0.1 2.6e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain E1_UFD PF09358.10 ORY82400.1 - 0.0078 16.9 0.0 0.02 15.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain Pyr_redox PF00070.27 ORY82400.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORY82400.1 - 0.059 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ORY82400.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sec1 PF00995.23 ORY82401.1 - 1.6e-116 390.9 0.0 1.8e-116 390.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family tRNA-synt_His PF13393.6 ORY82402.1 - 1.8e-39 135.8 0.2 4.6e-34 118.1 0.0 2.4 3 0 0 3 3 3 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ORY82402.1 - 2.8e-10 40.2 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 ORY82402.1 - 3.1e-07 30.4 6.4 3.1e-07 30.4 6.4 2.3 2 0 0 2 2 2 1 WHEP-TRS domain HGTP_anticodon2 PF12745.7 ORY82402.1 - 1.1e-06 28.4 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 ORY82402.1 - 0.23 10.5 0.5 2.8 7.0 0.1 2.4 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.19 ORY82402.1 - 0.36 11.5 4.4 0.93 10.1 4.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Bac_rhamnosid_C PF17390.2 ORY82403.1 - 4.3e-11 42.4 0.2 8.5e-11 41.5 0.2 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 ORY82403.1 - 0.0015 17.8 0.1 0.013 14.7 0.0 2.4 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain F-box-like PF12937.7 ORY82405.1 - 2.3e-05 24.2 0.1 6e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like CBP_BcsF PF11120.8 ORY82406.1 - 0.17 12.0 0.1 0.52 10.5 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Mito_carr PF00153.27 ORY82407.1 - 5.8e-49 164.0 0.5 1.1e-15 57.3 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein MotA_ExbB PF01618.16 ORY82407.1 - 0.046 13.5 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family FmiP_Thoc5 PF09766.9 ORY82408.1 - 1.9e-34 119.6 3.6 2.3e-34 119.3 3.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 KfrA_N PF11740.8 ORY82408.1 - 0.2 12.4 6.2 1.5 9.5 0.5 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term TMF_TATA_bd PF12325.8 ORY82408.1 - 0.85 9.9 7.8 4.3 7.6 3.0 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ATP-synt_E PF05680.12 ORY82409.1 - 3.2e-17 62.7 0.0 3.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF2300 PF10062.9 ORY82409.1 - 0.02 15.0 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) UPF0047 PF01894.17 ORY82410.1 - 2.5e-36 124.3 0.0 2.8e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DUF4165 PF13752.6 ORY82410.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Pkinase PF00069.25 ORY82412.1 - 2.2e-50 171.5 0.0 2.1e-44 151.9 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY82412.1 - 2.7e-29 102.2 0.0 1.2e-27 96.8 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY82412.1 - 9.6e-07 28.4 0.0 9.7e-06 25.1 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY82412.1 - 0.00026 19.9 0.3 0.00051 18.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 ORY82412.1 - 0.049 13.0 0.2 0.083 12.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY82412.1 - 0.13 12.1 0.7 0.38 10.7 0.7 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Tmemb_14 PF03647.13 ORY82413.1 - 7.9e-25 87.4 10.0 9e-25 87.2 10.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C F-box-like PF12937.7 ORY82414.1 - 0.022 14.6 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.25 ORY82415.1 - 8.9e-57 192.4 0.0 2.1e-34 119.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY82415.1 - 1.8e-21 76.6 0.0 7.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 ORY82415.1 - 0.00012 22.7 3.0 0.00064 20.4 3.0 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 ORY82415.1 - 0.0021 17.7 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY82415.1 - 0.0052 16.2 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY82415.1 - 0.0065 15.8 0.0 0.55 9.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY82415.1 - 0.018 13.9 0.0 0.049 12.4 0.0 1.7 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 ORY82415.1 - 0.046 13.6 0.3 0.28 11.1 0.3 2.1 1 1 0 1 1 1 0 Phosphotransferase enzyme family SMC_N PF02463.19 ORY82416.1 - 2.7e-69 232.9 0.0 6.8e-44 149.9 0.0 2.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY82416.1 - 2.5e-23 82.6 0.0 7e-23 81.2 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY82416.1 - 2.8e-11 43.8 9.2 2.3e-05 24.3 0.0 4.2 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY82416.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY82416.1 - 0.0025 18.3 25.7 0.0025 18.3 25.7 7.9 3 3 1 4 4 4 1 AAA domain Taxilin PF09728.9 ORY82416.1 - 0.11 11.6 82.1 0.0068 15.6 24.2 4.2 4 1 0 4 4 4 0 Myosin-like coiled-coil protein AAA_15 PF13175.6 ORY82416.1 - 2.1 7.9 42.6 0.02 14.6 14.7 4.6 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 ORY82416.1 - 4.7 7.7 20.2 1.1 9.8 0.0 5.8 4 2 0 4 4 4 0 ABC transporter Ank_5 PF13857.6 ORY82417.1 - 1.2e-13 51.0 0.2 4.9e-06 26.7 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY82417.1 - 3.6e-12 46.1 0.1 3.4e-05 24.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY82417.1 - 5.7e-11 41.6 0.0 0.00026 21.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY82417.1 - 2.5e-10 40.7 0.5 3.4e-06 27.5 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY82417.1 - 9.8e-10 38.9 0.0 1.4e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Amidohydro_1 PF01979.20 ORY82418.1 - 2e-56 191.8 0.0 6.3e-48 163.8 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ORY82418.1 - 1.8e-07 31.0 0.0 0.0013 18.3 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family DEAD PF00270.29 ORY82419.1 - 1.4e-39 135.6 0.0 2.4e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 ORY82419.1 - 7.4e-22 77.3 0.1 7.4e-22 77.3 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 ORY82419.1 - 4.7e-20 72.0 0.0 1.3e-19 70.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY82419.1 - 0.00093 19.2 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SBF_like PF13593.6 ORY82419.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) BLI1 PF17324.2 ORY82419.1 - 0.46 11.2 3.0 1.3 9.7 3.0 1.8 1 0 0 1 1 1 0 BLOC-1 interactor 1 SH3_1 PF00018.28 ORY82420.1 - 8.4e-12 44.5 0.0 1.5e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY82420.1 - 8.6e-09 35.0 0.1 2.2e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 ORY82420.1 - 4.6e-07 29.6 0.0 9.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 ORY82420.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 SH3 domain SH3_4 PF06347.13 ORY82420.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain DUF2770 PF10968.8 ORY82420.1 - 0.33 11.0 5.1 0.79 9.7 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) DUF962 PF06127.11 ORY82420.1 - 0.5 10.5 4.1 0.78 9.9 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF962) BatA PF07584.11 ORY82420.1 - 0.79 10.1 2.5 32 5.0 0.2 3.1 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal MASE3 PF17159.4 ORY82420.1 - 0.96 9.0 11.4 0.28 10.8 3.2 2.1 1 1 1 2 2 2 0 Membrane-associated sensor domain Osw5 PF17062.5 ORY82420.1 - 3.5 7.8 6.1 0.25 11.4 0.7 1.8 2 0 0 2 2 2 0 Outer spore wall 5 Sulfotransfer_3 PF13469.6 ORY82875.1 - 0.00019 21.9 0.0 0.00082 19.8 0.0 1.9 1 1 1 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORY82875.1 - 0.00073 19.1 0.0 0.027 13.9 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain DUF4798 PF16055.5 ORY82875.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4798) Ribonuc_L-PSP PF01042.21 ORY82876.1 - 2.5e-21 75.9 0.0 2.9e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Aa_trans PF01490.18 ORY82877.1 - 1.7e-39 135.7 28.9 2e-39 135.5 28.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Neur_chan_memb PF02932.16 ORY82877.1 - 0.09 12.8 0.1 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region S1FA PF04689.13 ORY82877.1 - 0.44 10.7 1.6 11 6.3 0.3 3.5 4 0 0 4 4 4 0 DNA binding protein S1FA DUF2157 PF09925.9 ORY82877.1 - 4.2 7.2 23.7 0.75 9.6 4.0 4.2 2 2 2 4 4 4 0 Predicted membrane protein (DUF2157) DCB PF16213.5 ORY82878.1 - 2.8e-37 128.1 0.1 6.2e-37 127.0 0.1 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 ORY82878.1 - 2.6e-36 125.1 0.3 3e-22 78.6 0.0 4.9 2 1 1 3 3 3 3 C-terminal region of Mon2 protein Sec7_N PF12783.7 ORY82878.1 - 1.7e-34 119.0 0.0 2.8e-32 111.8 0.0 3.6 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY82878.1 - 1.4e-05 24.8 0.0 7.7e-05 22.5 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) HEAT PF02985.22 ORY82878.1 - 0.13 12.6 0.9 12 6.5 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat SelK_SelG PF10961.8 ORY82878.1 - 0.15 12.7 4.8 0.77 10.4 4.8 2.2 1 0 0 1 1 1 0 Selenoprotein SelK_SelG SARAF PF06682.12 ORY82879.1 - 1.9e-64 218.4 1.3 2.3e-64 218.2 1.3 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis NAD_binding_6 PF08030.12 ORY82880.1 - 4.7e-22 78.8 0.0 6.6e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY82880.1 - 2.4e-16 60.0 11.1 2.4e-16 60.0 11.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY82880.1 - 5.4e-10 39.3 0.0 4.2e-09 36.5 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 ORY82880.1 - 0.95 10.1 16.1 0.38 11.3 2.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Glyco_hydro_47 PF01532.20 ORY82881.1 - 4.8e-98 329.0 0.0 7.6e-98 328.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 ORY82881.1 - 1.5e-10 40.9 0.1 3.2e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 PA domain Sulfotransfer_3 PF13469.6 ORY82882.1 - 0.00021 21.7 0.3 0.0022 18.4 0.0 2.1 1 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORY82882.1 - 0.0007 19.1 0.0 0.0039 16.7 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sde2_N_Ubi PF13019.6 ORY82883.1 - 2.7e-41 141.1 0.1 2.7e-41 141.1 0.1 2.2 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Fungal_trans PF04082.18 ORY82885.1 - 6.1e-22 77.9 0.0 1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY82885.1 - 1.8e-09 37.6 13.0 4e-09 36.4 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY82886.1 - 2.2e-20 72.8 0.0 3.3e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY82886.1 - 0.00041 20.4 3.3 0.00095 19.2 3.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 ORY82887.1 - 5.1e-106 354.7 0.0 5.9e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DNA_ligase_IV PF11411.8 ORY82887.1 - 0.0093 16.1 0.1 0.027 14.6 0.0 1.8 2 0 0 2 2 2 1 DNA ligase IV NAD_binding_10 PF13460.6 ORY82888.1 - 1.7e-10 41.1 0.5 8.7e-10 38.8 0.5 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY82888.1 - 1e-09 38.3 0.0 1.8e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY82888.1 - 1e-08 35.0 0.0 4.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ORY82888.1 - 0.00013 22.2 0.0 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Aldedh PF00171.22 ORY82889.1 - 1.3e-149 498.6 0.0 1.5e-149 498.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ndufs5 PF10200.9 ORY82891.1 - 0.00078 19.7 0.2 0.012 15.8 0.2 2.2 1 1 1 2 2 2 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.10 ORY82891.1 - 0.0086 16.1 0.5 0.011 15.7 0.5 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 ORY82891.1 - 0.058 13.6 0.5 2.5 8.4 0.1 2.2 2 0 0 2 2 2 0 CHCH domain KRE1 PF17056.5 ORY82891.1 - 0.11 12.3 0.5 8.4 6.2 0.0 2.3 2 1 0 2 2 2 0 Killer toxin-resistance protein 1 DUF3128 PF11326.8 ORY82891.1 - 0.28 11.6 3.9 3.2 8.2 3.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) WD40 PF00400.32 ORY82893.1 - 3.2e-30 103.7 9.8 4.8e-07 30.4 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY82893.1 - 3.3e-08 33.7 0.0 0.041 14.2 0.0 4.5 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY82893.1 - 0.0054 15.7 0.0 0.33 9.9 0.0 2.9 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY82893.1 - 0.013 14.1 0.1 2.7 6.4 0.0 2.8 2 1 0 2 2 2 0 Cytochrome D1 heme domain Aa_trans PF01490.18 ORY82896.1 - 6.7e-38 130.5 34.5 8e-38 130.2 34.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 ORY82896.1 - 0.00016 20.6 31.1 0.00016 20.6 31.1 2.2 1 1 1 2 2 2 1 Amino acid permease Neur_chan_memb PF02932.16 ORY82896.1 - 0.065 13.3 0.3 0.19 11.8 0.1 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GNAT_acetyltr_2 PF13718.6 ORY82898.1 - 6.7e-95 316.8 0.0 1.5e-94 315.7 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 ORY82898.1 - 5.2e-76 255.4 3.2 1.7e-75 253.7 3.2 1.9 1 1 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 ORY82898.1 - 4.8e-61 205.7 0.0 1.3e-60 204.3 0.0 1.8 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 ORY82898.1 - 5.8e-29 99.9 0.3 2.2e-28 98.0 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 ORY82898.1 - 0.032 14.5 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY82898.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4449 PF14613.6 ORY82899.1 - 4.9e-07 30.0 0.0 3e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) NCKAP5 PF15246.6 ORY82899.1 - 0.042 13.5 0.2 0.086 12.4 0.2 1.5 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Rad4 PF03835.15 ORY82900.1 - 2.9e-27 95.2 4.5 9.1e-27 93.6 4.5 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 ORY82900.1 - 4.3e-27 94.3 0.1 8.1e-27 93.5 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 ORY82900.1 - 4.6e-18 65.9 1.8 1.3e-17 64.5 0.2 2.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 ORY82900.1 - 9.7e-17 60.5 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 ORY82900.1 - 4e-05 24.0 0.5 0.00066 20.1 0.3 2.9 2 1 0 2 2 2 1 Transglutaminase-like superfamily AA_permease_2 PF13520.6 ORY82901.1 - 1.2e-64 218.8 50.6 1.4e-64 218.5 50.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY82901.1 - 1.2e-19 70.3 39.6 1.7e-19 69.8 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY82902.1 - 3.9e-63 213.8 50.9 4.6e-63 213.5 50.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY82902.1 - 1.8e-19 69.7 39.5 2.5e-19 69.2 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease Transferase PF02458.15 ORY82903.1 - 1.1e-31 110.0 0.0 1.6e-14 53.5 0.0 3.1 3 0 0 3 3 3 3 Transferase family Methyltransf_33 PF10017.9 ORY82904.1 - 3.6e-70 236.6 0.0 1.6e-56 191.7 0.0 2.4 2 1 0 2 2 2 2 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 ORY82904.1 - 1.1e-12 48.0 0.6 1.3e-07 31.5 0.4 2.5 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 ORY82904.1 - 7.1e-05 23.3 1.7 0.00018 22.0 1.7 1.8 1 0 0 1 1 1 1 DinB superfamily GCD14 PF08704.10 ORY82905.1 - 1.3e-88 296.8 0.7 1.2e-86 290.4 0.7 2.2 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 ORY82905.1 - 1.3e-08 34.8 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY82905.1 - 9.4e-07 28.8 0.0 1.6e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 ORY82905.1 - 0.00021 21.1 0.0 0.00058 19.6 0.0 1.8 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Ubie_methyltran PF01209.18 ORY82905.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY82905.1 - 0.0079 16.9 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF1682 PF07946.14 ORY82905.1 - 0.025 13.8 1.0 0.04 13.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Fibrillarin PF01269.17 ORY82905.1 - 0.036 13.2 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin MTS PF05175.14 ORY82905.1 - 0.11 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain DUF4551 PF15087.6 ORY82905.1 - 0.17 10.7 7.7 0.23 10.2 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NARP1 PF12569.8 ORY82905.1 - 0.42 9.5 4.3 0.57 9.0 4.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Lin-8 PF03353.15 ORY82905.1 - 1 8.8 6.5 1.5 8.3 6.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4746 PF15928.5 ORY82905.1 - 2.3 7.6 8.9 4.1 6.7 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Macoilin PF09726.9 ORY82905.1 - 5.9 5.3 8.1 9.8 4.6 8.1 1.3 1 0 0 1 1 1 0 Macoilin family Vfa1 PF08432.10 ORY82905.1 - 6.6 7.0 9.3 14 6.0 9.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nuc_sug_transp PF04142.15 ORY82906.1 - 1.4e-74 251.1 13.4 2.5e-69 233.9 10.6 2.0 2 0 0 2 2 2 2 Nucleotide-sugar transporter UAA PF08449.11 ORY82906.1 - 1.3e-06 27.8 11.2 1.4e-05 24.4 11.2 2.1 1 1 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 ORY82906.1 - 0.003 16.6 0.4 0.003 16.6 0.4 2.0 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like DUF1029 PF06269.12 ORY82906.1 - 0.37 10.9 2.8 7 6.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) Trp_oprn_chp PF09534.10 ORY82906.1 - 3.1 7.5 13.5 1.5 8.5 2.7 3.3 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF373 PF04123.13 ORY82906.1 - 9.5 5.5 7.0 6.8 6.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Epimerase PF01370.21 ORY82907.1 - 1.4e-38 132.7 0.0 1.9e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY82907.1 - 2.6e-38 132.3 0.0 3.2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY82907.1 - 1.3e-14 53.9 0.0 1.3e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY82907.1 - 4.6e-11 42.4 0.0 9e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY82907.1 - 2.2e-09 36.9 0.0 5.8e-08 32.2 0.0 2.2 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY82907.1 - 0.00013 21.2 0.0 0.0005 19.3 0.0 1.9 2 1 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 ORY82907.1 - 0.00027 20.9 0.0 0.00062 19.7 0.0 1.5 1 1 0 1 1 1 1 KR domain Acetyltransf_8 PF13523.6 ORY82908.1 - 1.4e-45 154.6 0.3 2.3e-45 153.8 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY82908.1 - 0.00016 22.4 0.1 0.00062 20.5 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-C3H1 PF10650.9 ORY82909.1 - 0.035 13.8 0.2 0.057 13.1 0.2 1.4 1 0 0 1 1 1 0 Putative zinc-finger domain Toxin_38 PF14866.6 ORY82909.1 - 0.36 11.2 0.9 0.67 10.3 0.9 1.4 1 0 0 1 1 1 0 Potassium channel toxin PHD PF00628.29 ORY82910.1 - 9.5e-10 38.2 9.9 1.8e-09 37.3 9.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-RRPl_C4 PF17026.5 ORY82910.1 - 0.1 12.7 0.7 0.16 12.0 0.7 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Prok-RING_1 PF14446.6 ORY82910.1 - 0.12 12.3 2.7 0.28 11.2 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 ORY82910.1 - 0.25 11.6 2.7 0.54 10.5 2.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger MAP65_ASE1 PF03999.12 ORY82910.1 - 0.3 9.7 3.8 0.66 8.6 3.8 1.5 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PHD_2 PF13831.6 ORY82910.1 - 2.9 7.5 8.8 0.92 9.1 5.1 2.0 2 0 0 2 2 2 0 PHD-finger Pns11_12 PF17464.2 ORY82910.1 - 9.8 5.8 6.3 18 4.9 6.3 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 Ribonuc_red_lgC PF02867.15 ORY82912.1 - 8.3e-176 585.6 0.0 1e-175 585.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 ORY82912.1 - 1.8e-23 82.3 0.1 5.3e-23 80.8 0.0 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 ORY82912.1 - 1.1e-15 57.9 0.1 2.5e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 ATP cone domain DUF4653 PF15546.6 ORY82912.1 - 0.48 10.0 2.5 0.76 9.4 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Med18 PF09637.10 ORY82913.1 - 4.7e-06 26.6 0.0 7.5e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 Med18 protein MalF_P2 PF14785.6 ORY82913.1 - 0.011 15.8 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain ATS3 PF06232.11 ORY82913.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) zf-HIT PF04438.16 ORY82914.1 - 3.5e-08 33.2 9.3 6.6e-08 32.3 9.3 1.5 1 0 0 1 1 1 1 HIT zinc finger Pex24p PF06398.11 ORY82915.1 - 1.4e-21 76.9 0.2 1.1e-20 74.0 0.0 1.9 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin PRT_C PF08372.10 ORY82915.1 - 0.0074 16.0 0.2 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal JAB PF01398.21 ORY82916.1 - 2.1e-27 95.4 0.0 4e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ORY82916.1 - 1.5e-12 47.9 0.3 2.3e-12 47.3 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 ORY82916.1 - 5.3e-06 26.2 0.0 9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF5624 PF18538.1 ORY82916.1 - 0.022 14.9 0.1 0.038 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) GCIP PF13324.6 ORY82917.1 - 7e-27 94.7 1.7 1e-26 94.1 1.7 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Nro1 PF12753.7 ORY82917.1 - 4.3e-06 25.9 0.9 7.1e-06 25.2 0.9 1.3 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 PBP1_TM PF14812.6 ORY82917.1 - 0.077 13.4 2.0 0.16 12.4 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 ORY82917.1 - 0.1 13.0 8.9 0.18 12.2 8.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNA_pol_3_Rpc31 PF11705.8 ORY82917.1 - 0.14 12.4 8.0 0.21 11.8 8.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 ORY82917.1 - 0.4 10.7 4.7 0.18 11.8 0.8 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.6 ORY82917.1 - 0.42 10.9 8.3 1 9.6 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RRN3 PF05327.11 ORY82917.1 - 0.69 8.4 5.0 1.4 7.3 5.0 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Drc1-Sld2 PF11719.8 ORY82917.1 - 1.5 8.3 6.4 5.2 6.5 4.0 2.1 2 0 0 2 2 2 0 DNA replication and checkpoint protein DUF2457 PF10446.9 ORY82917.1 - 3.6 6.6 10.5 5.2 6.1 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 ORY82917.1 - 6.5 6.0 8.8 8.9 5.5 8.8 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 ORY82917.1 - 7.2 6.3 8.6 2.7 7.6 5.6 1.8 2 0 0 2 2 2 0 FAM176 family FKBP_C PF00254.28 ORY82918.1 - 5.7e-32 109.9 0.0 7e-32 109.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Plk4_PB1 PF18190.1 ORY82920.1 - 0.00018 21.6 0.0 0.00036 20.7 0.0 1.5 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 1 POLO_box PF00659.18 ORY82920.1 - 0.16 12.2 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 POLO box duplicated region DUF1465 PF07323.12 ORY82920.1 - 0.21 11.4 0.0 0.38 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Fungal_trans PF04082.18 ORY82921.1 - 2.8e-25 88.9 0.0 4.6e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY82921.1 - 0.00082 19.4 9.7 0.0015 18.6 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zinc_ribbon_6 PF14599.6 ORY82921.1 - 0.47 10.5 2.5 1.4 9.0 2.3 1.9 2 0 0 2 2 2 0 Zinc-ribbon Sugar_tr PF00083.24 ORY82922.1 - 3.5e-79 266.8 20.0 3.9e-79 266.6 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY82922.1 - 6.4e-10 38.5 16.4 6.4e-10 38.5 16.4 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1479 PF07350.12 ORY82923.1 - 0.0002 20.3 0.0 0.068 11.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ORY82923.1 - 0.022 15.2 0.0 0.06 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PhyH PF05721.13 ORY82923.1 - 0.027 14.7 0.1 0.1 12.9 0.1 2.0 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) Cnd2 PF05786.14 ORY82924.1 - 6.5e-175 584.0 0.0 8.6e-175 583.5 0.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 ORY82924.1 - 0.00031 20.9 0.0 0.00067 19.9 0.0 1.5 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF4611 PF15387.6 ORY82924.1 - 0.35 11.1 14.1 0.41 10.9 1.9 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Arf PF00025.21 ORY82926.1 - 6.7e-45 152.7 0.0 8e-45 152.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY82926.1 - 9.1e-21 74.1 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY82926.1 - 1e-15 58.0 0.0 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY82926.1 - 8.5e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY82926.1 - 1.3e-07 31.2 0.0 1.6e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY82926.1 - 2.6e-07 30.7 0.0 4.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORY82926.1 - 1.8e-05 24.1 0.2 0.00067 18.9 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 ORY82926.1 - 0.02 14.4 0.1 0.041 13.4 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY82926.1 - 0.05 13.7 0.3 0.092 12.8 0.4 1.4 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 ORY82926.1 - 0.05 14.1 0.0 0.067 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF751 PF05421.11 ORY82926.1 - 0.071 13.8 0.1 0.14 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF751) AAA_7 PF12775.7 ORY82926.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 ORY82928.1 - 2.8e-46 158.1 50.9 2.8e-46 158.1 50.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY82928.1 - 1.1e-14 53.8 25.3 1.4e-14 53.4 25.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY82928.1 - 1.4e-13 50.5 14.1 1.4e-13 50.5 14.1 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2069 PF09842.9 ORY82928.1 - 3.9 7.7 12.9 0.17 12.1 5.0 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2069) Amidase PF01425.21 ORY82929.1 - 9.5e-64 216.0 0.0 5.2e-63 213.6 0.0 1.8 1 1 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 ORY82930.1 - 1.1e-13 51.2 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Oxidored_FMN PF00724.20 ORY82931.1 - 8.9e-80 268.5 0.0 1.1e-79 268.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family K_oxygenase PF13434.6 ORY82932.1 - 3.1e-81 273.2 0.0 2.1e-77 260.6 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY82932.1 - 0.016 14.4 0.0 0.026 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 ORY82933.1 - 5.9e-15 55.0 44.6 5.9e-15 55.0 44.6 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY82933.1 - 2.8e-06 26.1 26.7 4.6e-05 22.0 26.7 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GnRH PF00446.17 ORY82935.1 - 0.93 10.0 5.1 3.1 8.4 5.1 2.0 1 0 0 1 1 1 0 Gonadotropin-releasing hormone Hum_adeno_E3A PF05393.11 ORY82935.1 - 3.7 7.6 6.8 4.6 7.3 0.6 2.9 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein Amino_oxidase PF01593.24 ORY82936.1 - 1.2e-24 87.4 0.0 7.7e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY82936.1 - 2e-14 53.6 0.0 4e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY82936.1 - 2.4e-06 27.4 0.2 1.9e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY82936.1 - 7.2e-05 22.2 0.0 0.00089 18.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY82936.1 - 0.00049 19.3 0.1 0.00088 18.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY82936.1 - 0.00086 19.3 0.0 0.47 10.4 0.0 2.5 2 1 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY82936.1 - 0.0046 15.7 0.0 0.022 13.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 ORY82936.1 - 0.011 14.6 0.3 0.02 13.8 0.1 1.4 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.27 ORY82936.1 - 0.023 15.3 0.0 0.054 14.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY82936.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ORY82936.1 - 0.039 13.3 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 ORY82936.1 - 0.092 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 ORY82936.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Grg1 PF11034.8 ORY82938.1 - 4e-34 116.6 13.7 1.3e-28 99.0 6.6 2.1 2 0 0 2 2 2 2 Glucose-repressible protein Grg1 LcnG-beta PF11632.8 ORY82938.1 - 0.092 12.7 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Lactococcin G-beta TRC8_N PF13705.6 ORY82938.1 - 0.43 9.5 0.5 0.52 9.2 0.5 1.2 1 0 0 1 1 1 0 TRC8 N-terminal domain UAA PF08449.11 ORY82939.1 - 9.3e-40 136.7 2.8 1.4e-39 136.2 2.8 1.2 1 0 0 1 1 1 1 UAA transporter family Sulfotransfer_1 PF00685.27 ORY82939.1 - 1.4e-05 24.7 0.1 3.4e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Sulfotransferase domain EamA PF00892.20 ORY82939.1 - 2.5e-05 24.5 2.4 2.5e-05 24.5 2.4 3.2 3 1 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 ORY82939.1 - 0.00015 21.2 0.2 0.0003 20.2 0.2 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family Sulfotransfer_3 PF13469.6 ORY82939.1 - 0.0054 17.1 0.4 0.02 15.3 0.4 2.0 1 1 0 1 1 1 1 Sulfotransferase family PRP21_like_P PF12230.8 ORY82939.1 - 0.14 12.0 4.9 0.23 11.3 4.9 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein DUF1682 PF07946.14 ORY82939.1 - 2.1 7.5 4.9 3.1 6.9 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CMAS PF02353.20 ORY82940.1 - 1.7e-05 24.3 0.2 5.2e-05 22.7 0.2 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase CMAS PF02353.20 ORY82941.1 - 4e-06 26.3 0.2 1.4e-05 24.5 0.2 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase CMAS PF02353.20 ORY82942.1 - 2.2e-64 217.4 0.0 4.6e-64 216.4 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY82942.1 - 4.4e-07 30.5 0.0 9.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY82942.1 - 0.00022 21.1 0.0 0.00053 19.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY82942.1 - 0.00058 19.7 0.0 0.00096 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 ORY82942.1 - 0.004 16.9 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Catalase-rel PF06628.12 ORY82942.1 - 0.038 14.2 0.0 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Catalase-related immune-responsive Methyltransf_12 PF08242.12 ORY82942.1 - 0.076 13.8 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MADF_DNA_bdg PF10545.9 ORY82942.1 - 0.19 12.1 0.0 0.53 10.6 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like COPIIcoated_ERV PF07970.12 ORY82943.1 - 3.3e-85 285.4 0.2 4.3e-85 285.1 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY82943.1 - 7.3e-26 90.4 0.2 1.8e-25 89.1 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) p450 PF00067.22 ORY82944.1 - 1e-37 130.0 0.0 1.4e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C48 PF02902.19 ORY82945.1 - 3.3e-12 46.7 1.5 5.8e-12 45.9 1.5 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRN9 PF10680.9 ORY82945.1 - 0.13 12.6 0.1 0.25 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Mit_KHE1 PF10173.9 ORY82947.1 - 2.4e-53 181.1 1.7 4.4e-53 180.2 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related C_Hendra PF16821.5 ORY82948.1 - 2.5 8.0 7.1 0.91 9.4 3.5 1.9 2 0 0 2 2 2 0 C protein from hendra and measles viruses F-box-like PF12937.7 ORY82951.1 - 0.015 15.1 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like Complex1_LYR PF05347.15 ORY82952.1 - 0.00034 20.6 2.4 0.0049 16.9 2.4 2.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY82952.1 - 0.016 15.9 3.7 0.016 15.9 3.7 2.4 2 2 1 3 3 3 0 Complex1_LYR-like DUF1572 PF07609.11 ORY82952.1 - 0.44 10.3 2.5 6.9 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1572) Acetyltransf_10 PF13673.7 ORY82953.1 - 3.7e-10 39.8 0.0 2.3e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY82953.1 - 3.1e-07 30.6 0.0 4.8e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY82953.1 - 0.0002 21.7 0.0 0.0004 20.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY82953.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY82953.1 - 0.027 14.4 0.0 0.058 13.4 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_6 PF13480.7 ORY82953.1 - 0.093 12.9 0.2 0.38 10.9 0.0 2.0 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain DCP2 PF05026.13 ORY82954.1 - 3.8e-28 97.6 0.1 6e-28 97.0 0.1 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 ORY82954.1 - 4.8e-11 42.8 0.2 8.9e-11 42.0 0.2 1.4 1 0 0 1 1 1 1 NUDIX domain Grg1 PF11034.8 ORY82955.1 - 4e-34 116.6 13.7 1.3e-28 99.0 6.6 2.1 2 0 0 2 2 2 2 Glucose-repressible protein Grg1 LcnG-beta PF11632.8 ORY82955.1 - 0.092 12.7 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Lactococcin G-beta TRC8_N PF13705.6 ORY82955.1 - 0.43 9.5 0.5 0.52 9.2 0.5 1.2 1 0 0 1 1 1 0 TRC8 N-terminal domain Grg1 PF11034.8 ORY82959.1 - 6.1e-19 68.0 11.6 7.8e-19 67.7 11.6 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 BTB PF00651.31 ORY82960.1 - 1.1e-09 38.4 0.0 1.9e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Transferase PF02458.15 ORY82961.1 - 1.8e-33 115.8 0.0 2.5e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Transferase family Glycos_transf_4 PF00953.21 ORY82963.1 - 3.5e-32 111.6 9.7 7.6e-32 110.5 9.7 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 4 Sugar_tr PF00083.24 ORY82964.1 - 7.7e-105 351.4 15.6 9.1e-105 351.1 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY82964.1 - 3.2e-30 105.3 50.9 5.5e-28 97.9 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY82964.1 - 0.014 13.8 2.1 0.088 11.2 0.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector ScsC_N PF18312.1 ORY82965.1 - 0.21 11.4 0.3 0.3 10.9 0.3 1.3 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain DLH PF01738.18 ORY82966.1 - 2.6e-19 69.7 0.0 3e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DLH PF01738.18 ORY82967.1 - 2.5e-16 59.9 0.0 3.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BTB PF00651.31 ORY82968.1 - 4.5e-09 36.5 0.0 5.7e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Grg1 PF11034.8 ORY82969.1 - 7.5e-19 67.7 12.6 9.1e-19 67.5 12.6 1.1 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 BTB PF00651.31 ORY82970.1 - 4.1e-11 43.1 0.0 7.3e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 ORY82970.1 - 0.073 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Mad3_BUB1_I PF08311.12 ORY82971.1 - 1.5e-36 125.1 0.1 2.1e-36 124.6 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 ORY82971.1 - 9.3e-05 22.6 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase PF00069.25 ORY82972.1 - 2.1e-10 40.4 0.0 4.8e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY82972.1 - 8.9e-07 28.5 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY82972.1 - 0.076 12.4 0.1 0.69 9.2 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RXT2_N PF08595.11 ORY82972.1 - 2.1 8.4 16.7 21 5.1 5.1 3.7 3 0 0 3 3 3 0 RXT2-like, N-terminal Linker_histone PF00538.19 ORY82973.1 - 6.4e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 linker histone H1 and H5 family DUF5493 PF17597.2 ORY82974.1 - 0.093 13.0 0.5 0.26 11.6 0.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5493) FIST PF08495.10 ORY82975.1 - 2e-07 31.2 0.0 3.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 FIST N domain F-box-like PF12937.7 ORY82976.1 - 0.00078 19.3 1.7 0.0011 18.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY82976.1 - 1.6 8.7 6.2 0.35 10.8 1.1 2.6 2 1 0 2 2 2 0 F-box domain DUF1264 PF06884.11 ORY82977.1 - 2.3e-56 190.1 0.0 3.1e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) F-box-like PF12937.7 ORY82978.1 - 0.012 15.5 1.3 0.024 14.5 0.3 2.1 2 1 0 2 2 2 0 F-box-like F-box PF00646.33 ORY82978.1 - 0.15 12.0 2.2 1.3 9.0 2.2 2.4 1 1 0 1 1 1 0 F-box domain 3HCDH_N PF02737.18 ORY82979.1 - 7.2e-57 192.2 2.7 1.1e-56 191.6 2.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY82979.1 - 9.4e-32 109.5 0.0 2.1e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.21 ORY82979.1 - 0.00031 20.1 0.3 0.00054 19.3 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 ORY82979.1 - 0.00088 19.5 2.6 0.008 16.4 2.6 2.2 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORY82979.1 - 0.0015 18.2 1.3 0.0054 16.3 1.3 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORY82979.1 - 0.052 13.5 2.0 0.048 13.6 0.5 1.7 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.14 ORY82979.1 - 0.057 12.6 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OTCace PF00185.24 ORY82979.1 - 0.089 12.9 0.2 0.85 9.7 0.1 2.1 1 1 1 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain AMP-binding PF00501.28 ORY82981.1 - 2.7e-76 256.9 0.0 3.6e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY82981.1 - 0.00038 21.4 0.0 0.0042 18.0 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 ORY82986.1 - 4e-49 166.7 0.1 3.8e-28 98.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 ORY82986.1 - 3.6e-42 144.9 23.3 5.3e-26 91.9 2.0 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY82986.1 - 4.6e-10 39.3 4.2 0.02 14.3 0.3 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY82986.1 - 1.3e-07 32.1 0.4 0.0019 18.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY82986.1 - 3.4e-07 30.3 0.3 0.012 15.5 0.0 3.5 4 0 0 4 4 4 2 RsgA GTPase AAA_29 PF13555.6 ORY82986.1 - 3.6e-06 26.6 1.2 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY82986.1 - 0.00026 20.6 3.5 0.38 10.3 2.5 3.3 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORY82986.1 - 0.00039 20.3 4.2 0.5 10.1 0.1 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY82986.1 - 0.00058 19.9 0.1 1.6 8.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 ORY82986.1 - 0.0023 17.7 2.8 0.17 11.6 0.0 3.9 5 0 0 5 5 4 1 IstB-like ATP binding protein ATP-synt_ab PF00006.25 ORY82986.1 - 0.0024 17.6 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 ORY82986.1 - 0.0037 16.4 0.0 0.95 8.5 0.0 2.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_18 PF13238.6 ORY82986.1 - 0.0048 17.5 0.0 2.2 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY82986.1 - 0.0048 16.2 0.2 0.21 10.8 0.1 2.7 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.6 ORY82986.1 - 0.0079 16.5 1.2 5.3 7.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY82986.1 - 0.01 15.4 0.0 4.1 6.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 ORY82986.1 - 0.014 15.9 0.9 2.3 8.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY82986.1 - 0.022 15.0 0.0 8.1 6.7 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORY82986.1 - 0.026 14.3 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 ORY82986.1 - 0.032 14.5 1.1 12 6.2 0.0 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 ORY82986.1 - 0.035 14.0 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ORY82986.1 - 0.068 13.6 0.0 7.7 7.0 0.0 3.0 3 0 0 3 3 3 0 RNA helicase NACHT PF05729.12 ORY82986.1 - 0.08 12.8 0.2 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 ORY82986.1 - 0.082 13.0 0.3 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA PF00004.29 ORY82986.1 - 0.1 13.0 0.0 26 5.3 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORY82986.1 - 0.14 11.9 0.1 0.83 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ORY82986.1 - 0.14 11.3 0.0 0.8 8.9 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain AAA_5 PF07728.14 ORY82986.1 - 0.15 12.1 0.2 4.1 7.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.21 ORY82986.1 - 0.15 11.7 0.1 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase cobW PF02492.19 ORY82986.1 - 0.2 11.2 1.3 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ldh_1_C PF02866.18 ORY82987.1 - 1.2e-43 148.9 0.0 2.6e-43 147.8 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORY82987.1 - 1.5e-43 148.3 0.1 2.2e-43 147.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 ORY82987.1 - 7.7e-05 21.8 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 ORY82987.1 - 0.023 15.1 0.2 0.11 13.0 0.0 2.1 3 1 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain BTB PF00651.31 ORY82988.1 - 4.9e-18 65.4 0.0 2.2e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Yip1 PF04893.17 ORY82990.1 - 1.4e-20 73.8 14.5 1.8e-20 73.3 14.5 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 ORY82990.1 - 0.85 9.4 10.4 1.2 8.8 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) ubiquitin PF00240.23 ORY82992.1 - 1.9e-23 82.0 0.0 2.1e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY82992.1 - 3.9e-14 52.2 0.0 4.3e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY82992.1 - 1.9e-05 25.0 0.0 2.5e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY82992.1 - 0.021 14.7 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain F-box-like PF12937.7 ORY82993.1 - 0.0031 17.4 0.4 0.0074 16.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY82993.1 - 0.011 15.6 0.2 0.041 13.8 0.2 2.0 1 1 0 1 1 1 0 F-box domain EutQ PF06249.12 ORY82993.1 - 0.058 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF1264 PF06884.11 ORY82994.1 - 4.4e-57 192.4 0.0 6e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) F-box-like PF12937.7 ORY82995.1 - 0.00031 20.6 0.0 0.00088 19.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like Iso_dh PF00180.20 ORY82996.1 - 1.6e-67 228.1 0.0 1.9e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Acyltransferase PF01553.21 ORY82997.1 - 8.1e-11 41.7 0.0 1.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase zf-MYND PF01753.18 ORY82998.1 - 4.9e-06 26.5 19.5 1e-05 25.5 19.5 1.6 1 1 0 1 1 1 1 MYND finger Myb_DNA-bind_4 PF13837.6 ORY83000.1 - 0.0017 18.7 0.1 0.0075 16.6 0.0 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF4129 PF13559.6 ORY83000.1 - 0.002 18.4 1.3 0.0061 16.8 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) Myb_DNA-bind_6 PF13921.6 ORY83000.1 - 0.067 13.5 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain FAD-SLDH PF12318.8 ORY83001.1 - 0.039 14.0 0.2 0.088 12.9 0.2 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase RRM_3 PF08777.11 ORY83002.1 - 2.8e-05 24.1 0.0 2.8e-05 24.1 0.0 3.1 2 1 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 ORY83002.1 - 0.00099 18.9 0.0 0.0064 16.3 0.0 2.3 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR_2 PF13233.6 ORY83003.1 - 3e-18 66.4 0.2 4.5e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 ORY83003.1 - 7.7e-10 38.7 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Zn_clus PF00172.18 ORY83004.1 - 0.00017 21.6 13.8 0.00028 20.9 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY83005.1 - 3.3e-08 32.8 9.2 4.3e-08 32.5 9.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Telomere_reg-2 PF10193.9 ORY83468.1 - 7.4e-31 106.8 0.1 5.8e-30 103.9 0.0 2.6 4 0 0 4 4 4 1 Telomere length regulation protein LRR_2 PF07723.13 ORY83469.1 - 0.1 13.3 0.0 0.1 13.3 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 ORY83469.1 - 1.8 9.1 8.3 2.8 8.5 0.2 4.6 1 1 2 5 5 5 0 Leucine Rich repeats (2 copies) FA_desaturase PF00487.24 ORY83470.1 - 7e-14 52.3 21.9 7e-14 52.3 21.9 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY83470.1 - 5.4e-13 48.9 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Citrate_bind PF16114.5 ORY83471.1 - 3.1e-88 293.9 0.1 5.9e-88 293.0 0.1 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 ORY83471.1 - 1.2e-15 57.5 0.1 5e-13 48.9 0.1 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 ORY83471.1 - 2.1e-15 56.8 0.0 4e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 ORY83471.1 - 1e-13 51.8 0.0 2.8e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 ORY83471.1 - 2.1e-07 30.7 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ORY83471.1 - 4.3e-06 26.6 0.0 3.4e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Metallophos PF00149.28 ORY83472.1 - 2.1e-07 31.7 2.1 2.3e-07 31.5 0.9 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Amj PF10997.8 ORY83472.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.2 1 0 0 1 1 1 0 Alternate to MurJ F-box-like PF12937.7 ORY83473.1 - 9.2e-06 25.5 0.2 2.6e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like Chitin_synth_1 PF01644.17 ORY83474.1 - 1.7e-73 246.0 0.1 3.1e-73 245.1 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY83474.1 - 5e-29 101.3 1.4 3.4e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY83474.1 - 1e-25 89.5 0.1 2.1e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY83474.1 - 4.8e-10 39.7 0.7 1.1e-09 38.6 0.5 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY83474.1 - 4.2e-05 23.5 0.0 8.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 LRR19-TM PF15176.6 ORY83474.1 - 1.1 9.3 4.2 0.82 9.7 0.8 2.5 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain PgaD PF13994.6 ORY83475.1 - 0.0031 17.6 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 PgaD-like protein OppC_N PF12911.7 ORY83475.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Hydrolase_4 PF12146.8 ORY83476.1 - 7.9e-61 205.4 0.0 9.1e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY83476.1 - 1.6e-13 51.8 0.1 2.2e-13 51.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY83476.1 - 2.3e-13 50.4 0.1 8.6e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY83476.1 - 2.4e-07 30.5 1.0 1.3e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 ORY83476.1 - 2e-05 24.2 0.1 0.0073 15.9 0.0 2.4 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 ORY83476.1 - 2.7e-05 24.1 0.2 0.0008 19.3 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ORY83476.1 - 0.0012 18.7 0.1 0.039 13.7 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 ORY83476.1 - 0.0065 16.6 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 ORY83476.1 - 0.0079 15.9 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 ORY83476.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) SKIP_SNW PF02731.15 ORY83477.1 - 1.8e-71 239.0 1.3 1.8e-71 239.0 1.3 2.0 2 0 0 2 2 2 1 SKIP/SNW domain FAM199X PF15814.5 ORY83477.1 - 2.2 7.3 5.2 3.9 6.5 5.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X MFS_1 PF07690.16 ORY83479.1 - 1.5e-29 103.0 36.9 2.2e-28 99.2 36.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.9 ORY83479.1 - 0.098 12.9 3.3 0.61 10.3 0.2 2.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4227 PF14004.6 ORY83479.1 - 0.19 11.8 3.1 0.37 10.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) SPC25 PF06703.11 ORY83479.1 - 0.52 10.1 2.6 0.62 9.8 0.0 2.5 2 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Ribonucleas_3_3 PF14622.6 ORY83480.1 - 6.7e-05 23.1 0.0 0.00024 21.2 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY83480.1 - 6.8e-05 23.4 0.0 0.014 16.0 0.0 2.7 2 1 0 2 2 2 1 Ribonuclease III domain Ndc1_Nup PF09531.10 ORY83481.1 - 1.7 7.2 4.6 2.1 6.9 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L36e PF01158.18 ORY83482.1 - 2.3e-38 130.4 2.1 2.5e-38 130.2 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.7 ORY83482.1 - 0.039 13.5 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TetR_C_9 PF14514.6 ORY83482.1 - 0.053 13.7 0.1 0.064 13.4 0.1 1.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LemA PF04011.12 ORY83482.1 - 0.063 13.1 0.3 0.077 12.9 0.3 1.1 1 0 0 1 1 1 0 LemA family RMI1_C PF16099.5 ORY83482.1 - 0.085 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Recq-mediated genome instability protein 1, C-terminal OB-fold Ribosomal_L6e PF01159.19 ORY83483.1 - 9.6e-38 129.1 0.5 2.1e-37 128.1 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORY83483.1 - 0.00029 21.0 0.3 0.00096 19.4 0.3 2.0 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain CM_2 PF01817.21 ORY83485.1 - 0.0019 18.5 0.0 0.019 15.3 0.0 2.3 2 1 0 2 2 2 1 Chorismate mutase type II Peptidase_M16 PF00675.20 ORY83486.1 - 3.7e-51 173.0 0.2 6.3e-51 172.3 0.2 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY83486.1 - 2.2e-37 128.8 0.0 2.6e-35 122.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain MTD PF01993.18 ORY83486.1 - 0.067 12.5 0.0 0.32 10.3 0.0 1.9 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase HLH PF00010.26 ORY83488.1 - 6.5e-05 22.8 0.0 0.00016 21.5 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Ndc1_Nup PF09531.10 ORY83488.1 - 5.1 5.7 4.4 8.2 5.0 4.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup G_glu_transpept PF01019.21 ORY83489.1 - 1e-140 469.9 0.0 1.2e-140 469.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.16 ORY83490.1 - 1.1e-27 96.9 30.5 1.8e-27 96.2 30.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5483 PF17581.2 ORY83490.1 - 0.0032 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5483) Tic110 PF16940.5 ORY83490.1 - 0.042 12.3 1.3 0.063 11.8 1.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Zn_clus PF00172.18 ORY83491.1 - 3.9e-08 33.3 6.1 6.4e-08 32.6 6.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 ORY83491.1 - 0.0096 14.8 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugarporin_N PF11471.8 ORY83491.1 - 0.29 11.1 5.5 0.072 13.1 0.7 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension EF1G PF00647.19 ORY83492.1 - 2.5e-41 140.1 0.0 5.5e-41 138.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 ORY83492.1 - 2.6e-14 53.2 0.1 2.6e-14 53.2 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY83492.1 - 3.2e-09 37.0 0.2 1.8e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY83492.1 - 1.9e-06 28.0 0.1 4.2e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY83492.1 - 2.3e-06 27.9 0.0 1.1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY83492.1 - 1.4e-05 25.0 0.0 4.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EF1G PF00647.19 ORY83493.1 - 1.2e-41 141.0 0.0 2.4e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 ORY83493.1 - 1.2e-11 44.7 0.1 4.1e-11 42.9 0.1 1.8 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY83493.1 - 2.1e-08 34.4 0.0 1e-07 32.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY83493.1 - 7.3e-07 29.1 0.1 2.4e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY83493.1 - 4.7e-06 26.9 0.0 2.2e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY83493.1 - 0.00066 19.8 0.2 0.0021 18.2 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_tran PF00005.27 ORY83494.1 - 1.5e-34 119.4 0.0 3.5e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 ORY83494.1 - 4e-27 95.6 12.6 4e-27 95.6 12.6 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY83494.1 - 6.5e-07 29.0 0.4 1.3e-05 24.7 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY83494.1 - 0.0067 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 ORY83494.1 - 0.01 15.7 0.1 0.05 13.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY83494.1 - 0.01 16.1 0.1 0.057 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY83494.1 - 0.013 15.9 0.3 0.045 14.1 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORY83494.1 - 0.019 14.7 0.6 0.05 13.4 0.2 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY83494.1 - 0.08 12.7 0.1 0.21 11.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ORY83494.1 - 0.088 13.2 0.0 0.75 10.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ORY83494.1 - 0.12 12.1 0.0 0.34 10.6 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain TraX PF05857.11 ORY83494.1 - 0.92 9.5 6.4 0.068 13.2 1.1 1.7 2 0 0 2 2 2 0 TraX protein DUF4396 PF14342.6 ORY83494.1 - 4 7.8 7.1 0.33 11.3 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) Thr_synth_N PF14821.6 ORY83495.1 - 3.9e-27 94.3 0.0 9.2e-27 93.1 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 ORY83495.1 - 4.1e-12 46.1 0.0 1.5e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BLACT_WH PF17778.1 ORY83495.1 - 0.057 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain GST_C_3 PF14497.6 ORY83496.1 - 0.002 18.3 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_16 PF00722.21 ORY83497.1 - 3.6e-07 29.8 0.0 8.2e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DPBB_1 PF03330.18 ORY83498.1 - 1.7e-07 31.4 0.2 7.7e-07 29.3 0.2 2.2 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY83498.1 - 0.0042 16.9 0.9 0.0042 16.9 0.9 2.5 1 1 1 3 3 3 1 Barwin family EB PF01683.18 ORY83498.1 - 0.19 12.0 4.8 0.38 11.1 4.8 1.5 1 0 0 1 1 1 0 EB module DUF3452 PF11934.8 ORY83499.1 - 0.19 11.3 0.0 0.42 10.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) CYSTM PF12734.7 ORY83500.1 - 4.9e-05 23.6 72.2 1.1e+02 3.2 72.2 4.1 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance AIRC PF00731.20 ORY83502.1 - 1.1e-62 210.0 0.3 2.3e-62 208.9 0.3 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 ORY83502.1 - 3.5e-46 156.9 0.0 2.1e-44 151.1 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain PurK_C PF17769.1 ORY83502.1 - 7.7e-17 60.7 0.1 1.8e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 ORY83502.1 - 0.0022 17.5 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain UPF0014 PF03649.13 ORY83502.1 - 0.081 12.3 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) DUF1297 PF06973.12 ORY83502.1 - 0.15 11.6 0.0 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1297) Glyco_hydro_42M PF08532.10 ORY83503.1 - 0.045 13.2 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain ThylakoidFormat PF11264.8 ORY83504.1 - 0.01 15.6 0.2 0.015 15.0 0.2 1.2 1 0 0 1 1 1 0 Thylakoid formation protein Cyclin PF08613.11 ORY83505.1 - 1.6e-29 103.4 0.0 6.4e-29 101.4 0.0 1.8 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY83505.1 - 0.00071 19.3 0.0 0.0014 18.4 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain PAS_9 PF13426.7 ORY83506.1 - 9.7e-13 48.3 0.0 1.1e-12 48.1 0.0 1.0 1 0 0 1 1 1 1 PAS domain TM140 PF14985.6 ORY83509.1 - 0.16 11.5 0.9 0.26 10.8 0.9 1.2 1 0 0 1 1 1 0 TM140 protein family CDC45 PF02724.14 ORY83510.1 - 8 4.6 7.1 16 3.6 7.1 1.4 1 0 0 1 1 1 0 CDC45-like protein SUZ PF12752.7 ORY83511.1 - 9.2e-13 48.7 2.1 9.2e-13 48.7 2.1 4.3 4 1 0 4 4 4 1 SUZ domain MFS_1 PF07690.16 ORY83513.1 - 1.2e-21 77.1 32.0 1.2e-21 77.1 32.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY83513.1 - 0.00043 19.7 25.0 0.00062 19.2 25.0 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 ORY83514.1 - 1.5e-20 73.5 69.4 3.1e-19 69.1 36.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Mito_carr PF00153.27 ORY83515.1 - 8e-61 202.0 2.1 3.2e-22 78.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 ORY83515.1 - 2.5e-10 40.7 1.2 5e-10 39.7 1.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY83515.1 - 3.7e-09 35.5 4.9 6e-06 25.4 0.4 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 ORY83515.1 - 9.8e-08 31.3 0.1 0.013 15.3 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY83515.1 - 4.4e-06 25.9 2.3 2.3e-05 23.7 0.5 2.7 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 ORY83515.1 - 0.00087 19.6 0.1 0.0015 18.8 0.1 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 ORY83515.1 - 0.016 15.0 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair Ribosomal_60s PF00428.19 ORY83515.1 - 0.11 13.1 9.7 3.3 8.4 1.3 3.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein WD40 PF00400.32 ORY83516.1 - 9.1e-11 42.2 2.5 0.0022 18.8 0.1 6.7 6 1 0 6 6 6 2 WD domain, G-beta repeat HALZ PF02183.18 ORY83516.1 - 0.053 13.7 0.1 0.099 12.9 0.1 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper 60KD_IMP PF02096.20 ORY83517.1 - 6.6e-11 42.4 0.0 0.00013 21.9 0.0 2.8 2 1 0 2 2 2 2 60Kd inner membrane protein Costars PF14705.6 ORY83519.1 - 8.2e-24 83.6 0.1 9.2e-24 83.4 0.1 1.0 1 0 0 1 1 1 1 Costars Actin PF00022.19 ORY83520.1 - 4.7e-108 361.4 0.0 2e-107 359.3 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY83520.1 - 0.071 11.9 0.0 0.53 9.0 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein adh_short_C2 PF13561.6 ORY83522.1 - 4.4e-50 170.4 2.6 5.6e-50 170.1 2.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY83522.1 - 2.5e-40 138.0 2.9 3.3e-40 137.7 2.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY83522.1 - 3.4e-11 43.4 2.0 1.4e-10 41.4 2.0 1.8 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 ORY83522.1 - 0.1 13.3 0.0 0.26 12.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain ACOX PF01756.19 ORY83524.1 - 9.4e-51 171.9 0.0 4.5e-50 169.7 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORY83524.1 - 3.7e-18 65.5 0.1 7.5e-18 64.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORY83524.1 - 2.1e-12 47.7 0.0 6e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 ORY83524.1 - 1.2e-07 32.1 1.3 1.5e-06 28.5 1.2 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Meth_synt_2 PF01717.18 ORY83526.1 - 4.7e-150 499.3 0.0 1.2e-144 481.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY83526.1 - 1.2e-111 373.3 0.0 5.3e-107 358.0 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Fungal_trans PF04082.18 ORY83527.1 - 1.3e-17 63.8 0.4 3.4e-17 62.4 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY83527.1 - 6.4e-06 26.2 10.1 1.1e-05 25.4 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY83528.1 - 1.7e-06 28.1 11.5 2.8e-06 27.3 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 ORY83528.1 - 0.59 10.5 10.9 0.93 9.9 10.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) YniB PF14002.6 ORY83530.1 - 0.068 12.9 0.3 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 YniB-like protein Neur_chan_memb PF02932.16 ORY83530.1 - 0.069 13.2 0.4 0.087 12.9 0.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SIT PF15330.6 ORY83530.1 - 0.17 12.3 1.1 0.43 11.0 1.1 1.8 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1180 PF06679.12 ORY83530.1 - 0.32 11.4 3.7 0.54 10.7 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) SRP-alpha_N PF04086.13 ORY83530.1 - 1.3 8.9 15.5 1.8 8.4 15.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 ORY83530.1 - 1.5 7.5 4.1 2.3 6.9 4.1 1.3 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 ORY83530.1 - 2.3 6.9 7.3 3 6.5 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3807 PF12720.7 ORY83530.1 - 5.2 7.3 16.6 8.4 6.6 16.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Glyco_hydro_63 PF03200.16 ORY83531.1 - 4.4e-06 25.7 10.3 5.3e-06 25.5 0.5 4.0 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain NmrA PF05368.13 ORY83532.1 - 2e-40 138.8 0.0 2.3e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY83532.1 - 1e-10 41.8 0.0 1.6e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY83532.1 - 0.00029 20.4 0.1 0.00041 19.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY83532.1 - 0.0052 17.2 0.1 0.0087 16.5 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 ORY83532.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus HpcH_HpaI PF03328.14 ORY83534.1 - 1.5e-52 177.9 0.0 2.3e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ORY83534.1 - 9.8e-19 67.7 0.0 3.2e-09 36.4 0.0 2.3 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Ste5_C PF12194.8 ORY83535.1 - 0.042 13.8 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein kinase Fus3-binding ABC_tran_CTD PF16326.5 ORY83535.1 - 2.1 8.6 22.7 0.074 13.3 3.4 5.4 4 1 0 5 5 5 0 ABC transporter C-terminal domain RNA_pol_N PF01194.17 ORY83536.1 - 1.1e-28 99.3 0.4 1.2e-28 99.2 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit OATP PF03137.20 ORY83537.1 - 0.041 12.2 0.8 0.05 11.9 0.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family zf-MYND PF01753.18 ORY83538.1 - 2.1e-07 30.9 9.1 2.1e-07 30.9 9.1 1.7 2 0 0 2 2 2 1 MYND finger FAT PF02259.23 ORY83540.1 - 7.7e-70 235.8 4.0 1.4e-69 235.0 3.4 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORY83540.1 - 4.1e-32 112.0 0.1 8.1e-32 111.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ecm29 PF13001.7 ORY83540.1 - 0.00093 18.0 0.4 0.95 8.1 0.0 3.8 4 0 0 4 4 4 2 Proteasome stabiliser FATC PF02260.20 ORY83540.1 - 0.0025 17.6 0.2 0.0066 16.2 0.2 1.8 1 0 0 1 1 1 1 FATC domain DUF1744 PF08490.12 ORY83540.1 - 0.0075 14.9 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) MIF4G PF02854.19 ORY83540.1 - 0.15 11.6 1.4 0.69 9.5 0.0 2.9 3 0 0 3 3 3 0 MIF4G domain Adaptin_N PF01602.20 ORY83540.1 - 0.57 8.7 5.1 0.21 10.1 0.2 2.8 3 0 0 3 3 3 0 Adaptin N terminal region RPN2_C PF18004.1 ORY83540.1 - 1.9 8.4 9.7 0.39 10.6 5.0 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Zn_clus PF00172.18 ORY83541.1 - 1.6e-06 28.1 10.9 2.5e-06 27.5 10.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_5 PF14634.6 ORY83542.1 - 8.2e-07 28.9 1.5 4.1e-05 23.5 0.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY83542.1 - 6.4e-06 25.9 5.9 7.5e-06 25.7 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY83542.1 - 6.7e-06 25.9 2.2 6.7e-06 25.9 2.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY83542.1 - 6.9e-06 26.0 7.3 3.2e-05 23.9 5.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY83542.1 - 4.6e-05 23.2 5.7 0.003 17.4 1.9 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY83542.1 - 4.7e-05 23.6 5.4 0.00015 22.0 1.0 2.2 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 ORY83542.1 - 0.16 11.9 11.5 0.92 9.4 6.9 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY83542.1 - 0.53 10.5 8.4 0.31 11.2 4.1 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY83542.1 - 5 7.0 6.7 30 4.5 1.6 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Auto_anti-p27 PF06677.12 ORY83542.1 - 8 6.7 8.2 2.8 8.2 0.2 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MFS_1 PF07690.16 ORY83543.1 - 5.8e-30 104.4 19.9 5.8e-30 104.4 19.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 ORY83543.1 - 1.6 8.7 9.6 0.11 12.4 0.4 3.0 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Zn_clus PF00172.18 ORY83545.1 - 1.5e-09 37.8 9.5 2.2e-09 37.3 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRAL_TRIO PF00650.20 ORY83546.1 - 1.9e-24 86.2 0.0 2.6e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY83546.1 - 1e-09 38.4 0.0 3.8e-09 36.6 0.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain WD40 PF00400.32 ORY83547.1 - 0.00012 22.8 0.3 0.8 10.7 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat GCFC PF07842.12 ORY83548.1 - 1.5e-08 34.6 0.0 8.2e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein HBS1_N PF08938.10 ORY83548.1 - 1.1 9.5 8.4 11 6.5 0.2 2.8 2 0 0 2 2 2 0 HBS1 N-terminus Shadoo PF14999.6 ORY83549.1 - 0.0026 17.9 0.5 0.0096 16.0 0.5 2.0 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective zf-RanBP PF00641.18 ORY83550.1 - 0.0015 17.8 0.4 0.0033 16.7 0.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF3454 PF11936.8 ORY83550.1 - 1.1 9.7 4.8 1.5 9.3 1.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3454) Histone PF00125.24 ORY83551.1 - 1.5e-17 64.2 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 ORY83551.1 - 2e-11 43.4 0.2 2e-11 43.4 0.2 1.8 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 ORY83551.1 - 0.023 15.0 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MPP6 PF10175.9 ORY83552.1 - 0.0001 22.8 0.1 0.0001 22.8 0.1 2.9 2 1 0 2 2 2 1 M-phase phosphoprotein 6 Astro_capsid_p PF12226.8 ORY83552.1 - 1.9 7.6 6.0 2.9 7.0 6.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 ORY83552.1 - 6.7 6.4 19.9 81 2.8 19.9 2.0 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein COPI_C PF06957.11 ORY83552.1 - 7.9 5.1 9.3 13 4.4 9.3 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DNA_pol_phi PF04931.13 ORY83552.1 - 8.1 4.4 11.7 12 3.9 11.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi bZIP_2 PF07716.15 ORY83553.1 - 6.4e-06 26.1 16.5 1.3e-05 25.1 16.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY83553.1 - 2.1e-05 24.5 16.3 4e-05 23.6 16.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor BBP1_C PF15272.6 ORY83553.1 - 0.086 12.7 1.6 0.14 12.0 1.6 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal bZIP_Maf PF03131.17 ORY83553.1 - 0.12 12.9 9.2 0.25 11.9 9.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF1465 PF07323.12 ORY83553.1 - 0.51 10.2 3.3 0.9 9.4 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) GAS PF13851.6 ORY83553.1 - 0.72 9.2 8.8 1.1 8.6 8.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.16 ORY83555.1 - 7.1e-30 104.1 20.2 7.1e-30 104.1 20.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 ORY83555.1 - 1.6 8.7 9.4 0.13 12.2 0.4 3.0 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus SNARE_assoc PF09335.11 ORY83556.1 - 1.1e-15 58.1 7.4 3.3e-15 56.6 7.4 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein FAD_binding_4 PF01565.23 ORY83557.1 - 1.6e-29 102.4 1.1 2.5e-29 101.8 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY83557.1 - 2e-13 50.2 0.2 4.7e-13 49.0 0.2 1.7 1 0 0 1 1 1 1 Berberine and berberine like Toxin_ToxA PF11584.8 ORY83557.1 - 0.043 13.8 0.1 0.091 12.8 0.1 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Ribosomal_L7Ae PF01248.26 ORY83558.1 - 5.5e-23 80.5 1.4 5.5e-23 80.5 1.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mlf1IP PF10248.9 ORY83558.1 - 0.0024 17.9 1.0 0.023 14.7 0.1 2.1 2 0 0 2 2 2 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein TPR_1 PF00515.28 ORY83560.1 - 1.4e-12 46.8 7.1 0.00017 21.2 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY83560.1 - 8.6e-10 38.0 14.9 0.00054 19.9 0.4 5.3 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY83560.1 - 1.6e-06 27.7 0.8 5.3e-05 22.8 0.4 2.9 1 1 1 2 2 2 1 TPR repeat TPR_12 PF13424.6 ORY83560.1 - 0.00023 21.4 4.0 0.00023 21.4 4.0 3.2 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY83560.1 - 0.00048 20.7 1.4 0.00048 20.7 1.4 3.7 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY83560.1 - 0.026 14.7 0.4 0.084 13.0 0.4 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 ORY83560.1 - 0.028 12.8 0.0 0.043 12.2 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal DUF4007 PF13182.6 ORY83560.1 - 0.085 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4007) TPR_7 PF13176.6 ORY83560.1 - 0.1 12.7 2.7 1.3 9.2 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY83560.1 - 0.13 12.6 9.8 0.59 10.5 0.0 4.4 6 0 0 6 6 4 0 Tetratricopeptide repeat ChAPs PF09295.10 ORY83560.1 - 0.17 10.8 0.7 0.28 10.2 0.7 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 ORY83560.1 - 0.19 12.6 8.7 5.5 8.1 1.2 4.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY83560.1 - 0.23 11.9 1.5 21 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY83560.1 - 0.64 10.6 8.4 0.57 10.7 1.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Tubulin PF00091.25 ORY83561.1 - 1.2e-67 228.0 0.0 1.7e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY83561.1 - 5.9e-48 162.2 0.0 8.8e-48 161.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY83561.1 - 0.00032 20.4 0.0 0.00098 18.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Peptidase_S24 PF00717.23 ORY83562.1 - 1.6e-08 34.4 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Sarcolipin PF05366.11 ORY83562.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Sarcolipin tRNA-synt_2c PF01411.19 ORY83563.1 - 0.0016 17.0 0.0 0.0025 16.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) Uds1 PF15456.6 ORY83564.1 - 1.1e-29 103.3 2.1 1.1e-29 103.3 2.1 7.2 3 2 3 6 6 6 1 Up-regulated During Septation Tropomyosin PF00261.20 ORY83564.1 - 0.0018 17.7 45.0 0.0018 17.7 45.0 5.0 3 2 0 4 4 4 2 Tropomyosin CENP-F_leu_zip PF10473.9 ORY83564.1 - 0.0089 16.0 5.7 0.0089 16.0 5.7 7.2 4 2 2 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 ORY83564.1 - 0.055 13.5 40.2 0.061 13.4 1.4 6.6 3 2 4 7 7 7 0 Protein of unknown function (DUF1664) Filament PF00038.21 ORY83564.1 - 3.1 7.3 90.2 2.5 7.6 7.0 3.7 2 2 1 3 3 3 0 Intermediate filament protein AAA_13 PF13166.6 ORY83564.1 - 3.4 6.2 59.4 0.018 13.8 22.1 3.4 2 1 1 3 3 3 0 AAA domain TspO_MBR PF03073.15 ORY83565.1 - 1.9e-43 147.7 10.9 2.2e-43 147.5 10.9 1.0 1 0 0 1 1 1 1 TspO/MBR family BTB_2 PF02214.22 ORY83566.1 - 3e-06 27.5 0.0 0.086 13.2 0.0 2.6 2 0 0 2 2 2 2 BTB/POZ domain HTH_36 PF13730.6 ORY83566.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain ORC6 PF05460.13 ORY83566.1 - 0.15 11.3 0.0 0.15 11.3 0.0 2.8 2 1 1 3 3 3 0 Origin recognition complex subunit 6 (ORC6) RLL PF10036.9 ORY83566.1 - 2.3 8.0 3.5 0.89 9.4 0.9 1.6 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein adh_short_C2 PF13561.6 ORY83567.1 - 1.4e-62 211.4 0.4 1.8e-62 211.0 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY83567.1 - 6.5e-46 156.3 0.5 1e-45 155.6 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY83567.1 - 6.4e-13 49.0 0.1 1.2e-12 48.2 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY83567.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY83567.1 - 0.0058 15.8 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein HAD_2 PF13419.6 ORY83568.1 - 3.7e-07 30.4 0.0 6.8e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY83568.1 - 0.00011 22.6 0.0 0.00019 21.8 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0183 PF03676.14 ORY83569.1 - 1.4e-65 222.1 0.0 5.4e-65 220.2 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) F-box-like PF12937.7 ORY83570.1 - 0.00017 21.4 0.1 0.00043 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like NOA36 PF06524.12 ORY83570.1 - 0.019 14.3 4.9 0.03 13.7 4.9 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 ORY83570.1 - 0.074 13.1 1.0 0.14 12.1 1.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 ORY83570.1 - 0.39 10.4 2.5 0.78 9.4 2.5 1.5 1 0 0 1 1 1 0 FAM176 family LRR_6 PF13516.6 ORY83570.1 - 0.94 9.7 2.5 37 4.7 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat RNA_pol_3_Rpc31 PF11705.8 ORY83570.1 - 1.2 9.3 11.8 2.3 8.4 9.9 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 ORY83570.1 - 2.4 6.2 7.4 3.3 5.7 7.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 ORY83570.1 - 5.8 7.4 11.3 12 6.3 11.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Acyl-CoA_dh_N PF02771.16 ORY83572.1 - 1.8e-38 131.7 0.0 3.7e-38 130.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY83572.1 - 3.6e-38 131.1 0.5 5.6e-38 130.5 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY83572.1 - 2.3e-25 88.6 0.0 4.2e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY83572.1 - 5.8e-12 46.0 0.0 8.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AgrD PF05931.11 ORY83572.1 - 0.15 12.1 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein RVT_1 PF00078.27 ORY83575.1 - 0.0099 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 ORY83577.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) ETC_C1_NDUFA4 PF04800.12 ORY83579.1 - 1.8e-35 121.0 0.3 2.5e-35 120.6 0.3 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region MCPVI PF02993.14 ORY83579.1 - 0.59 9.9 3.3 0.48 10.2 2.1 1.4 2 0 0 2 2 2 0 Minor capsid protein VI Zn_clus PF00172.18 ORY83580.1 - 1.4e-06 28.3 7.0 2.3e-06 27.6 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AOX PF01786.17 ORY83581.1 - 1.2e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.17 ORY83582.1 - 1.4e-51 175.1 0.3 2e-51 174.7 0.3 1.2 1 0 0 1 1 1 1 Alternative oxidase Cytomega_UL84 PF06284.11 ORY83582.1 - 0.0098 14.4 0.2 0.012 14.2 0.2 1.0 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein Con-6 PF10346.9 ORY83583.1 - 4.5e-10 39.4 6.8 1.8e-05 24.6 0.6 2.2 2 0 0 2 2 2 2 Conidiation protein 6 BA14K PF07886.11 ORY83583.1 - 0.71 9.8 3.7 13 5.8 0.3 2.8 2 1 1 3 3 3 0 BA14K-like protein CsbD PF05532.12 ORY83584.1 - 8e-17 60.9 16.6 1.2e-09 37.9 2.8 2.0 1 1 1 2 2 2 2 CsbD-like G6PD_C PF02781.16 ORY83585.1 - 8e-114 379.7 0.0 1.3e-113 379.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORY83585.1 - 3.5e-62 210.2 0.1 5.8e-62 209.4 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 ORY83586.1 - 2.2e-44 151.8 0.0 2.5e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Abhydrolase_3 PF07859.13 ORY83587.1 - 6.9e-49 166.6 0.0 1.1e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY83587.1 - 8.7e-18 64.3 0.0 1.7e-17 63.4 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORY83587.1 - 0.0015 18.1 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORY83587.1 - 0.0022 17.9 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY83587.1 - 0.013 14.8 0.0 0.052 12.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 ORY83587.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) COesterase PF00135.28 ORY83587.1 - 0.1 11.5 0.0 0.34 9.7 0.0 1.9 1 1 0 1 1 1 0 Carboxylesterase family RNB PF00773.19 ORY83588.1 - 4e-103 345.2 0.0 6.2e-103 344.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY83588.1 - 3.4e-27 94.3 0.0 7.2e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORY83588.1 - 2.1e-24 85.6 0.0 6.8e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 ORY83588.1 - 0.00031 20.8 0.0 0.18 12.0 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 ORY83588.1 - 0.0062 16.5 0.0 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 S1 domain Rrp44_CSD1 PF17216.3 ORY83588.1 - 0.02 14.6 0.9 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 Rrp44-like cold shock domain 2OG-FeII_Oxy_3 PF13640.6 ORY83589.1 - 1.2e-06 29.3 0.0 3.2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.7 ORY83590.1 - 0.00025 20.8 1.1 0.00085 19.2 1.2 1.9 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY83590.1 - 0.042 14.3 4.9 7.3 7.2 0.1 3.8 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 ORY83591.1 - 9.2e-42 143.2 39.1 9.2e-42 143.2 39.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY83591.1 - 1.6e-18 66.5 21.7 2.1e-18 66.1 21.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.16 ORY83591.1 - 2.2 8.0 11.0 0.02 14.6 2.0 2.2 2 1 0 2 2 2 0 Ion channel regulatory protein UNC-93 Peptidase_S28 PF05577.12 ORY83593.1 - 3.3e-44 151.4 0.0 1.8e-34 119.3 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Shisa PF13908.6 ORY83595.1 - 0.018 15.3 0.0 0.02 15.1 0.0 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PrmA PF06325.13 ORY83596.1 - 5.7e-15 55.5 0.0 2.5e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORY83596.1 - 2.2e-11 44.3 0.0 4.4e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY83596.1 - 1.3e-09 38.0 0.0 2.8e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY83596.1 - 2.3e-09 37.8 0.0 5.8e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY83596.1 - 1.4e-08 34.5 0.5 3.9e-08 33.0 0.4 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY83596.1 - 6.2e-08 33.3 0.1 1.2e-05 25.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY83596.1 - 8.7e-08 32.2 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY83596.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORY83596.1 - 3.3e-06 26.7 0.0 7.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB PRMT5 PF05185.16 ORY83596.1 - 4.2e-05 23.5 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 ORY83596.1 - 6.3e-05 22.8 0.1 0.0001 22.1 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 ORY83596.1 - 0.00082 19.2 0.2 0.0029 17.4 0.1 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 ORY83596.1 - 0.0011 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORY83596.1 - 0.0012 17.9 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 ORY83596.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 ORY83596.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.6 ORY83596.1 - 0.022 15.8 0.0 0.057 14.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 ORY83596.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 ORY83596.1 - 0.034 14.2 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 ORY83596.1 - 0.037 13.6 0.0 0.1 12.1 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase TrmK PF04816.12 ORY83596.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Ribosomal_L4 PF00573.22 ORY83597.1 - 2.4e-37 128.5 1.9 2.4e-37 128.5 1.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ORY83597.1 - 6e-29 99.9 4.1 1.8e-26 92.0 3.2 2.4 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain Tcp11 PF05794.13 ORY83598.1 - 7e-104 348.4 0.0 2.1e-103 346.8 0.0 1.7 1 1 0 1 1 1 1 T-complex protein 11 MOSC_N PF03476.16 ORY83599.1 - 1.4e-21 76.6 0.0 2.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 ORY83599.1 - 4.1e-19 68.9 0.0 7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain GTP_EFTU_D2 PF03144.25 ORY83599.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 2 PRP1_N PF06424.12 ORY83600.1 - 3.6e-26 92.3 6.3 1.6e-25 90.2 5.0 2.5 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 ORY83600.1 - 7.2e-21 73.1 29.5 0.059 14.2 0.1 13.2 7 3 6 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY83600.1 - 8.7e-17 61.4 13.8 0.00069 20.1 0.1 9.9 8 2 1 9 9 9 4 Tetratricopeptide repeat Suf PF05843.14 ORY83600.1 - 0.0033 17.4 0.0 5.9 6.8 0.0 3.7 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) CAF-1_p150 PF11600.8 ORY83600.1 - 0.025 14.3 5.3 0.06 13.0 5.3 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TPR_17 PF13431.6 ORY83600.1 - 0.055 13.9 0.0 3.6 8.2 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ORY83600.1 - 0.31 10.9 2.7 6.1 6.7 0.0 3.4 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 ORY83600.1 - 2.6 8.9 0.0 2.6 8.9 0.0 6.1 9 0 0 9 9 9 0 Tetratricopeptide repeat AMMECR1 PF01871.17 ORY84067.1 - 1.2e-41 142.1 0.0 4.4e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 AMMECR1 AhpC-TSA PF00578.21 ORY84068.1 - 3.5e-33 114.1 0.0 4.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY84068.1 - 1.8e-12 47.2 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY84068.1 - 7.6e-11 41.7 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 ORY84068.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Transp_cyt_pur PF02133.15 ORY84069.1 - 1.1e-104 350.7 39.1 1.4e-104 350.4 39.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 1-cysPrx_C PF10417.9 ORY84070.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Utp14 PF04615.13 ORY84072.1 - 8.5e-182 606.6 52.5 8.5e-182 606.6 52.5 2.3 1 1 1 2 2 2 1 Utp14 protein VWA PF00092.28 ORY84073.1 - 3.6e-06 27.3 0.0 5.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain GRP PF07172.11 ORY84073.1 - 0.034 14.8 4.9 0.057 14.1 4.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family VWA_3 PF13768.6 ORY84073.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Pex14_N PF04695.13 ORY84073.1 - 4.4 7.9 13.7 9.3 6.9 13.7 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3425 PF11905.8 ORY84074.1 - 4.1e-13 49.4 0.5 2.8e-12 46.7 0.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 ORY84074.1 - 3.6e-09 36.6 6.8 1.2e-08 35.0 6.8 1.9 1 1 0 1 1 1 1 bZIP transcription factor CRISPR_Cse2 PF09485.10 ORY84074.1 - 0.0059 17.1 0.4 0.8 10.2 0.0 2.4 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) SIKE PF05769.11 ORY84074.1 - 0.65 9.9 6.1 0.1 12.5 1.7 1.8 2 0 0 2 2 2 0 SIKE family bZIP_2 PF07716.15 ORY84074.1 - 2 8.6 15.1 0.093 12.8 7.9 2.6 2 1 0 2 2 2 0 Basic region leucine zipper Sec7 PF01369.20 ORY84075.1 - 3.2e-71 238.8 0.0 8e-71 237.5 0.0 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 ORY84075.1 - 2.4e-46 157.5 3.1 2.4e-46 157.5 3.1 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY84075.1 - 7.9e-33 112.2 9.5 1e-32 111.8 0.1 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 ORY84075.1 - 4.1e-21 75.4 1.6 6.8e-18 65.0 0.2 4.5 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 ORY84075.1 - 0.0074 14.5 0.1 0.095 10.8 0.0 2.1 2 0 0 2 2 2 1 C-terminal region of Mon2 protein Phage_r1t_holin PF16945.5 ORY84075.1 - 0.068 13.4 7.7 0.19 12.0 1.5 2.9 2 0 0 2 2 2 0 Putative lactococcus lactis phage r1t holin Nop PF01798.18 ORY84076.1 - 2.1e-86 289.1 0.2 6.9e-86 287.4 0.0 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORY84076.1 - 5.3e-18 65.2 1.3 5.3e-18 65.2 1.3 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain SRP-alpha_N PF04086.13 ORY84076.1 - 0.21 11.5 25.4 0.29 11.0 25.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Sigma70_ner PF04546.13 ORY84076.1 - 1.2 8.9 15.2 0.32 10.9 11.9 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region MAT1 PF06391.13 ORY84076.1 - 5 6.9 20.1 9 6.1 20.1 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 ATG22 PF11700.8 ORY84077.1 - 3.6e-114 382.0 9.8 4.1e-114 381.8 9.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY84077.1 - 3.2e-06 26.3 46.4 8.9e-05 21.6 27.1 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily TssN PF17555.2 ORY84077.1 - 0.0045 16.4 2.6 0.0076 15.7 2.6 1.3 1 0 0 1 1 1 1 Type VI secretion system, TssN Chlam_vir PF05475.11 ORY84077.1 - 0.17 11.6 0.1 0.31 10.8 0.1 1.3 1 0 0 1 1 1 0 Pgp3 C-terminal domain PilX_N PF14341.6 ORY84077.1 - 3.2 7.8 0.0 3.2 7.8 0.0 3.8 4 0 0 4 4 4 0 PilX N-terminal F-box-like PF12937.7 ORY84078.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 F-box-like CDT1_C PF16679.5 ORY84079.1 - 7.3e-12 45.6 3.5 8e-12 45.4 0.1 2.8 2 1 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Dynamitin PF04912.14 ORY84082.1 - 3.3e-59 201.2 2.3 2.1e-58 198.5 2.3 2.0 1 1 0 1 1 1 1 Dynamitin ZapB PF06005.12 ORY84082.1 - 0.00011 22.6 1.5 0.012 16.0 0.1 2.8 2 0 0 2 2 2 1 Cell division protein ZapB TPR_MLP1_2 PF07926.12 ORY84082.1 - 0.04 14.0 3.5 0.37 10.9 0.0 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DASH_Dad2 PF08654.10 ORY84082.1 - 0.073 13.5 1.8 6.5 7.2 0.1 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 Cwf_Cwc_15 PF04889.12 ORY84082.1 - 0.082 12.6 1.9 0.14 11.9 1.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SlyX PF04102.12 ORY84082.1 - 0.75 10.5 9.5 6 7.6 0.0 4.3 5 0 0 5 5 5 0 SlyX Y_phosphatase2 PF03162.13 ORY84083.1 - 0.0067 16.0 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Nop14 PF04147.12 ORY84083.1 - 1.1 7.4 7.1 1.5 7.0 7.1 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 ORY84083.1 - 1.6 8.0 11.2 1.5 8.1 9.1 1.8 2 0 0 2 2 2 0 NOA36 protein KIND PF16474.5 ORY84083.1 - 2.6 7.9 6.5 5.1 7.0 6.5 1.4 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain SURF2 PF05477.11 ORY84083.1 - 6.5 6.4 6.7 9.4 5.8 6.6 1.3 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 ORY84083.1 - 8 4.4 13.8 11 4.0 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SPRY PF00622.28 ORY84084.1 - 0.00018 21.6 0.2 0.0026 17.9 0.1 2.4 3 0 0 3 3 3 1 SPRY domain Ytp1 PF10355.9 ORY84085.1 - 9.4e-57 192.3 29.8 2.4e-56 191.0 23.6 2.8 1 1 2 3 3 3 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORY84085.1 - 3.9e-21 74.8 0.2 3.9e-21 74.8 0.2 4.3 5 0 0 5 5 5 2 Domain of unknown function (DUF2427) RIX1 PF08167.12 ORY84086.1 - 0.034 13.9 0.2 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis DNA_ligase_IV PF11411.8 ORY84086.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA ligase IV PTPlike_phytase PF14566.6 ORY84087.1 - 0.0001 22.5 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 ORY84087.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY84087.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY84087.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_L12 PF00542.19 ORY84088.1 - 6.7e-20 71.2 7.9 1.9e-17 63.4 4.5 2.2 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 ORY84088.1 - 1.9e-13 49.8 12.5 2e-13 49.8 7.5 2.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF1179 PF06678.11 ORY84088.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1179) CCDC24 PF15669.5 ORY84088.1 - 0.2 11.5 1.8 0.85 9.4 0.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Pheromone PF08015.11 ORY84088.1 - 2.2 9.4 7.2 1.8 9.7 4.2 2.2 1 1 1 2 2 2 0 Fungal mating-type pheromone MutS_V PF00488.21 ORY84089.1 - 4.7e-54 183.3 0.0 8.8e-54 182.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY84089.1 - 1.2e-33 116.9 2.5 2.8e-33 115.8 2.5 1.6 1 0 0 1 1 1 1 MutS domain III DUF1400 PF07176.11 ORY84089.1 - 0.00079 19.7 1.4 1.7 8.9 0.0 3.9 4 0 0 4 4 4 1 Alpha/beta hydrolase of unknown function (DUF1400) MutS_II PF05188.17 ORY84089.1 - 0.0033 17.7 0.0 0.012 15.9 0.0 2.0 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY84089.1 - 0.0044 17.3 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 ORY84089.1 - 0.014 15.1 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 ORY84089.1 - 0.027 14.1 0.1 0.22 11.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 ORY84089.1 - 0.15 12.1 0.1 0.65 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 ORY84089.1 - 0.28 10.3 1.6 0.76 8.9 0.0 2.3 3 0 0 3 3 3 0 G-protein alpha subunit AAA_23 PF13476.6 ORY84089.1 - 0.35 11.4 0.0 0.35 11.4 0.0 2.4 3 1 0 3 3 3 0 AAA domain PC-Esterase PF13839.6 ORY84091.1 - 0.22 11.3 0.0 0.6 9.8 0.0 1.7 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p COX15-CtaA PF02628.15 ORY84092.1 - 4.2e-103 344.8 2.1 8.1e-103 343.9 2.1 1.4 1 1 0 1 1 1 1 Cytochrome oxidase assembly protein BolA PF01722.18 ORY84093.1 - 7.9e-11 42.1 0.0 1.3e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein Stb3 PF10330.9 ORY84093.1 - 0.043 13.9 0.0 4.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Putative Sin3 binding protein MRC1 PF09444.10 ORY84094.1 - 1.9e-17 64.2 24.0 1.9e-17 64.2 24.0 8.6 9 1 1 10 10 10 4 MRC1-like domain HSF_DNA-bind PF00447.17 ORY84095.1 - 4e-15 56.2 0.0 6.1e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ras PF00071.22 ORY84096.1 - 4.6e-45 153.1 0.0 2.5e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY84096.1 - 1.1e-31 109.5 0.0 1.6e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY84096.1 - 8e-11 41.7 0.0 1.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY84096.1 - 0.00028 20.3 0.0 0.00041 19.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY84096.1 - 0.00039 20.5 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY84096.1 - 0.0032 16.9 0.0 0.0049 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY84096.1 - 0.093 13.1 0.4 0.26 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain Ssu72 PF04722.13 ORY84097.1 - 1.3e-85 285.8 0.0 1.6e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Fungal_trans PF04082.18 ORY84098.1 - 2.8e-13 49.5 0.0 4.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY84098.1 - 3.6e-06 27.0 8.8 6.6e-06 26.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Not3 PF04065.15 ORY84100.1 - 3.1e-90 301.6 27.3 3.1e-90 301.6 27.3 1.7 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 ORY84100.1 - 8.1e-45 152.1 8.1 8.1e-45 152.1 8.1 2.6 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 ORY84100.1 - 0.075 12.9 5.0 0.16 11.8 5.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.11 ORY84100.1 - 0.47 10.5 3.6 1.3 9.1 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) MnmE_helical PF12631.7 ORY84100.1 - 3.6 7.7 9.4 0.47 10.6 4.3 2.0 1 1 1 2 2 2 0 MnmE helical domain cNMP_binding PF00027.29 ORY84101.1 - 4.7e-37 126.0 0.2 2.6e-18 65.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain SH3_3 PF08239.11 ORY84101.1 - 1.8 8.9 5.3 3.4 8.0 0.2 2.9 4 0 0 4 4 4 0 Bacterial SH3 domain DUF1772 PF08592.11 ORY84102.1 - 5.2e-18 65.7 1.4 6.5e-18 65.4 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Rho_GDI PF02115.17 ORY84103.1 - 6.8e-58 195.6 0.0 8.1e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Transp_cyt_pur PF02133.15 ORY84106.1 - 1.7e-35 122.7 39.3 2.4e-35 122.2 38.9 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YqhR PF11085.8 ORY84106.1 - 0.51 10.2 5.3 1.8 8.5 5.3 1.9 1 0 0 1 1 1 0 Conserved membrane protein YqhR D123 PF07065.14 ORY84107.1 - 1.2e-106 356.4 0.9 3.3e-106 354.9 0.9 1.6 1 1 0 1 1 1 1 D123 R2K_3 PF14243.6 ORY84107.1 - 0.00017 21.7 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 ORY84107.1 - 0.0045 16.9 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 DAO PF01266.24 ORY84108.1 - 3.3e-35 122.3 0.4 4e-35 122.0 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY84108.1 - 3.1e-06 26.7 0.0 0.0057 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY84108.1 - 6.5e-05 22.2 0.2 0.0015 17.7 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY84108.1 - 0.00013 22.0 0.0 0.46 10.4 0.0 2.5 1 1 1 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 ORY84108.1 - 0.00016 20.9 0.1 0.01 14.9 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY84108.1 - 0.00029 21.3 0.0 0.034 14.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY84108.1 - 0.0014 17.4 0.0 0.085 11.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORY84108.1 - 0.0035 16.7 0.0 0.57 9.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY84108.1 - 0.0039 17.4 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 ORY84108.1 - 0.011 15.9 0.1 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 ORY84108.1 - 0.058 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 ORY84108.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 ORY84108.1 - 0.08 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 ORY84108.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 ORY84108.1 - 0.17 12.4 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding LRRNT_2 PF08263.12 ORY84109.1 - 5.9 7.3 10.7 0.12 12.7 0.8 3.2 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain G-patch PF01585.23 ORY84110.1 - 2.1e-12 46.7 1.4 2.1e-12 46.7 1.4 2.5 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 ORY84110.1 - 4e-10 39.4 0.0 0.00078 19.2 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 ORY84110.1 - 0.00026 21.0 0.5 0.00026 21.0 0.5 2.3 3 0 0 3 3 3 1 G-patch domain zf-C2H2_jaz PF12171.8 ORY84110.1 - 0.024 14.9 1.3 0.044 14.1 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY84110.1 - 0.15 12.4 0.1 0.27 11.6 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RdRP PF05183.12 ORY84111.1 - 2.7e-14 52.7 0.0 3.5e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase Rep_fac_C PF08542.11 ORY84111.1 - 0.21 12.0 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Replication factor C C-terminal domain Ion_trans_2 PF07885.16 ORY84113.1 - 4e-29 100.4 26.3 9.6e-18 63.9 11.1 2.7 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 ORY84113.1 - 3.6e-07 29.7 7.9 0.00018 20.8 0.0 2.7 2 1 0 2 2 2 2 Ion transport protein CopD PF05425.13 ORY84113.1 - 0.09 13.2 3.8 0.71 10.3 0.3 3.4 3 0 0 3 3 3 0 Copper resistance protein D IRK PF01007.20 ORY84113.1 - 1.6 8.5 6.0 0.8 9.5 0.6 2.7 2 1 1 3 3 3 0 Inward rectifier potassium channel transmembrane domain Peptidase_S49_N PF08496.10 ORY84113.1 - 3.2 7.8 9.6 0.18 11.9 0.9 2.9 2 1 0 2 2 2 0 Peptidase family S49 N-terminal YfhO PF09586.10 ORY84113.1 - 3.3 5.8 8.6 1.3 7.1 0.2 2.3 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Nepo_coat_C PF03688.14 ORY84114.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain zf-MYND PF01753.18 ORY84115.1 - 4.2e-11 42.7 7.1 4.2e-11 42.7 7.1 2.3 2 1 0 2 2 2 1 MYND finger Topoisom_bac PF01131.20 ORY84116.1 - 4.1e-106 355.5 0.0 4.9e-106 355.2 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.12 ORY84116.1 - 1.3e-27 95.6 12.0 1.8e-13 50.3 3.1 2.7 2 0 0 2 2 2 2 GRF zinc finger Toprim PF01751.22 ORY84116.1 - 1.6e-17 63.6 0.0 6.6e-17 61.6 0.0 2.0 2 0 0 2 2 2 1 Toprim domain zf-CCHC PF00098.23 ORY84116.1 - 9.7e-15 53.9 21.3 3e-06 27.0 1.3 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 ORY84116.1 - 1.2e-07 31.5 18.5 0.0023 17.7 1.1 3.6 3 0 0 3 3 3 3 Zinc knuckle eIF3g PF12353.8 ORY84116.1 - 0.0013 19.1 10.3 0.17 12.3 0.2 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 ORY84116.1 - 0.0034 17.3 13.5 1.1 9.2 0.4 3.6 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 ORY84116.1 - 0.71 9.6 10.3 4.7 7.0 0.5 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Mce4_CUP1 PF11887.8 ORY84117.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Golgin_A5 PF09787.9 ORY84117.1 - 0.066 12.7 5.2 0.16 11.4 5.2 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 Rab5-bind PF09311.11 ORY84117.1 - 0.11 11.9 3.0 0.088 12.2 1.1 1.6 1 1 0 1 1 1 0 Rabaptin-like protein DUF2353 PF09789.9 ORY84117.1 - 1.2 8.5 7.7 2 7.7 7.7 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4407 PF14362.6 ORY84117.1 - 9.4 5.5 8.0 23 4.2 8.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hist_deacetyl PF00850.19 ORY84118.1 - 1.6e-70 238.0 0.0 2.1e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ABC_membrane PF00664.23 ORY84119.1 - 8.6e-41 140.4 8.4 1.1e-40 140.1 8.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY84119.1 - 2.5e-35 122.0 0.0 6.3e-35 120.7 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 ORY84119.1 - 1.7e-05 24.4 0.1 0.012 15.0 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 ORY84119.1 - 0.0016 18.9 0.0 0.013 15.9 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY84119.1 - 0.0025 18.2 0.0 0.0062 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY84119.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY84119.1 - 0.028 14.2 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 ORY84119.1 - 0.037 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 ORY84119.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORY84119.1 - 0.051 13.6 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY84119.1 - 0.061 13.1 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 ORY84119.1 - 0.078 13.0 0.0 0.4 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORY84119.1 - 0.089 12.8 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY84119.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SIR2 PF02146.17 ORY84120.1 - 1e-21 77.7 0.1 4.5e-06 26.7 0.0 3.3 3 0 0 3 3 3 3 Sir2 family Cse1 PF08506.10 ORY84121.1 - 3.1e-131 437.6 0.1 4.9e-131 436.9 0.1 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 ORY84121.1 - 2e-128 428.6 0.0 4.2e-128 427.6 0.0 1.5 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 ORY84121.1 - 1.2e-11 44.4 0.6 4.5e-10 39.3 0.1 3.6 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 ORY84121.1 - 0.00012 22.2 1.9 0.047 13.7 0.0 4.5 5 1 0 5 5 5 1 Exportin 1-like protein DDT PF02791.17 ORY84121.1 - 1.3 9.3 7.2 4.4 7.7 0.1 4.1 4 0 0 4 4 4 0 DDT domain Hormone_recep PF00104.30 ORY84122.1 - 0.088 12.4 0.4 0.091 12.3 0.4 1.0 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Glutaredoxin PF00462.24 ORY84123.1 - 5.4e-19 68.2 0.0 8.6e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 ORY84123.1 - 4e-05 23.6 0.0 5.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 ORY84123.1 - 9.6e-05 22.4 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 ORY84123.1 - 0.00048 20.5 0.0 0.00074 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 ORY84123.1 - 0.0025 18.2 0.1 0.0064 16.9 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 ORY84123.1 - 0.0083 16.3 0.6 3.6 7.7 0.3 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin PF00085.20 ORY84123.1 - 0.024 14.6 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin GST_N_3 PF13417.6 ORY84123.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ATG13 PF10033.9 ORY84124.1 - 5.9e-67 225.9 0.0 7.6e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 AhpC-TSA PF00578.21 ORY84125.1 - 3.2e-25 88.4 0.0 5e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY84125.1 - 1.3e-14 54.2 0.0 1.9e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin GATase_5 PF13507.6 ORY84126.1 - 2.3e-92 308.8 0.0 3.6e-92 308.1 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 ORY84126.1 - 2.6e-42 144.6 0.6 1.6e-28 99.8 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 ORY84126.1 - 7.8e-34 116.1 0.0 1.7e-33 115.1 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 ORY84126.1 - 6.9e-21 74.5 0.0 1.6e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Sulfatase PF00884.23 ORY84127.1 - 5.9e-60 203.3 0.1 7.8e-60 202.9 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ORY84127.1 - 3e-12 46.7 2.4 1.4e-11 44.5 2.4 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 ORY84127.1 - 3.1e-05 23.7 0.2 0.0017 18.0 0.0 2.5 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sugar_tr PF00083.24 ORY84128.1 - 2.2e-63 214.7 22.0 2.4e-63 214.6 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY84128.1 - 7.6e-14 51.4 41.7 3e-12 46.1 18.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 ORY84129.1 - 6.4e-13 48.6 28.3 1.9e-06 27.8 8.3 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY84129.1 - 8.5e-12 44.7 0.5 1.4e-11 44.0 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4802 PF16060.5 ORY84129.1 - 0.032 14.4 5.2 0.091 12.9 5.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) Peptidase_M48 PF01435.18 ORY84130.1 - 1.1e-11 44.8 0.0 1.3e-10 41.4 0.0 2.5 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_S8 PF00082.22 ORY84131.1 - 2.5e-40 138.6 2.1 4.1e-40 137.9 2.1 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY84131.1 - 4.6e-08 33.8 0.5 8.9e-08 32.8 0.5 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORY84131.1 - 0.00016 21.6 0.0 0.00079 19.4 0.0 2.2 2 0 0 2 2 2 1 PA domain Peptidase_S8 PF00082.22 ORY84132.1 - 7.6e-49 166.6 0.6 1.7e-48 165.4 0.6 1.5 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY84132.1 - 1.9e-10 41.4 0.8 3.8e-10 40.5 0.8 1.5 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORY84132.1 - 2.2e-09 37.2 0.5 1.9e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 PA domain Proteasome PF00227.26 ORY84133.1 - 1e-37 129.5 0.0 1.2e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit p450 PF00067.22 ORY84134.1 - 1.6e-59 201.9 0.0 6.6e-58 196.6 0.0 2.8 1 1 0 1 1 1 1 Cytochrome P450 DUF3007 PF11460.8 ORY84134.1 - 0.036 14.3 0.0 0.096 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Acetyltransf_1 PF00583.25 ORY84135.1 - 3.2e-10 40.2 0.0 1.9e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY84135.1 - 2.5e-07 31.0 0.1 1.1e-06 29.0 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY84135.1 - 4.6e-06 26.6 0.0 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY84135.1 - 7.3e-05 22.7 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_CG PF14542.6 ORY84135.1 - 0.024 14.8 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 ORY84135.1 - 0.032 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase RII_binding_1 PF10522.9 ORY84135.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 RII binding domain GNAT_acetyltr_2 PF13718.6 ORY84135.1 - 0.38 10.1 1.5 0.69 9.3 1.5 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase 2 AAA_13 PF13166.6 ORY84135.1 - 0.39 9.3 1.8 0.5 8.9 1.8 1.0 1 0 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.19 ORY84135.1 - 1.7 9.3 20.1 0.074 13.6 12.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein CPSF73-100_C PF11718.8 ORY84136.1 - 2.7e-61 206.9 0.0 5.7e-61 205.8 0.0 1.5 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 ORY84136.1 - 1.5e-28 99.3 0.0 3.1e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 ORY84136.1 - 2.7e-19 70.0 0.1 1e-18 68.0 0.0 2.0 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY84136.1 - 3.5e-16 59.2 0.0 8.7e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 ORY84136.1 - 6e-15 54.9 0.0 1.4e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORY84136.1 - 1.3e-06 28.1 0.1 1.8e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY84136.1 - 1.5e-06 28.2 0.0 1e-05 25.5 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Josephin PF02099.17 ORY84137.1 - 2.3e-44 151.4 0.0 4.8e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Josephin Nucleo_P87 PF07267.11 ORY84137.1 - 1.9 7.3 10.0 0.24 10.2 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RAP80_UIM PF18282.1 ORY84137.1 - 2.5 7.9 6.4 0.4 10.5 0.9 2.5 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif OAD_gamma PF04277.13 ORY84137.1 - 3.1 8.5 9.5 1.9 9.1 2.1 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Oxidored_molyb PF00174.19 ORY84138.1 - 3.6e-54 183.0 0.0 8.7e-54 181.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY84138.1 - 3.6e-50 169.6 0.1 5.9e-50 168.9 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 ORY84138.1 - 1.5e-24 86.2 0.0 2.8e-15 56.5 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY84138.1 - 4.3e-23 82.0 0.0 7.5e-22 78.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 ORY84138.1 - 1.7e-19 69.7 0.0 3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 ORY84138.1 - 0.0056 16.8 0.0 0.034 14.3 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 ORY84139.1 - 5.4e-34 117.8 0.1 8.9e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 ORY84139.1 - 2.2e-20 72.7 0.0 3.9e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Rieske_2 PF13806.6 ORY84139.1 - 3e-19 68.9 0.0 9.4e-19 67.3 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 ORY84139.1 - 2.2e-12 47.1 7.8 5e-09 36.4 6.5 2.7 2 0 0 2 2 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 ORY84139.1 - 2.2e-12 46.7 0.7 4.9e-10 39.2 0.0 2.6 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 ORY84139.1 - 2.6e-11 43.9 0.1 1e-10 42.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR_ferr PF03460.17 ORY84139.1 - 4.2e-10 39.3 0.0 8.5e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 ORY84139.1 - 6.1e-08 32.5 0.1 0.00077 19.3 0.1 2.9 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain Fungal_trans PF04082.18 ORY84140.1 - 1.5e-10 40.6 0.0 2.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY84140.1 - 0.0026 17.8 13.0 0.0044 17.1 13.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY84141.1 - 4.4e-15 55.4 0.2 7.6e-15 54.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY84141.1 - 0.0023 18.0 10.7 0.0038 17.3 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 ORY84142.1 - 4.4e-65 219.7 0.0 5.5e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY84142.1 - 9.2e-30 103.8 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY84142.1 - 0.0037 16.3 0.1 0.0058 15.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY84142.1 - 0.0074 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY84142.1 - 0.038 13.9 0.2 0.12 12.2 0.1 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 ORY84142.1 - 0.13 13.2 0.0 0.42 11.6 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat 4HBT_3 PF13622.6 ORY84143.1 - 8.5e-16 59.0 0.3 1.2e-15 58.5 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Robl_LC7 PF03259.17 ORY84144.1 - 1.2e-10 41.0 0.1 1.8e-07 30.8 0.1 2.2 2 0 0 2 2 2 2 Roadblock/LC7 domain DUF3540 PF12059.8 ORY84144.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) SET PF00856.28 ORY84145.1 - 5.4e-06 26.9 0.9 1e-05 26.0 0.0 2.0 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 ORY84145.1 - 0.00044 20.7 17.8 0.00044 20.7 17.8 4.6 3 1 2 5 5 5 2 CXC domain DUF2786 PF10979.8 ORY84146.1 - 4.3e-08 32.9 0.1 4.3e-08 32.9 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2786) Nop14 PF04147.12 ORY84146.1 - 3.4 5.8 11.3 7.3 4.7 11.3 1.6 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 ORY84146.1 - 4.8 6.8 7.8 0.15 11.7 1.7 1.7 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Acetyltransf_1 PF00583.25 ORY84147.1 - 8.7e-07 29.2 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY84147.1 - 1.9e-05 24.6 0.0 4.8e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY84147.1 - 2.7e-05 24.5 0.0 3.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY84147.1 - 7.1e-05 22.7 0.1 0.00015 21.7 0.1 1.5 1 1 0 1 1 1 1 FR47-like protein DUF5579 PF17742.1 ORY84147.1 - 0.04 13.5 0.1 9.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5579) IMS PF00817.20 ORY84148.1 - 3.9e-40 137.3 0.0 6.2e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 ORY84148.1 - 3.5e-10 40.6 0.0 8.4e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 ORY84148.1 - 0.00015 21.3 4.0 0.00099 18.7 0.9 2.4 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 ORY84148.1 - 0.0069 16.7 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif CDC27 PF09507.10 ORY84148.1 - 4.7 6.5 7.4 0.23 10.8 0.3 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Pkinase PF00069.25 ORY84149.1 - 7.5e-56 189.4 0.0 9.2e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY84149.1 - 7.3e-35 120.5 0.0 1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY84149.1 - 3.8e-05 23.2 0.0 5.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY84149.1 - 0.001 17.9 0.0 0.0015 17.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY84149.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Aminotran_3 PF00202.21 ORY84150.1 - 2.4e-118 395.3 0.0 2.8e-118 395.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY84150.1 - 3.8e-05 23.0 0.0 5.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF448 PF04296.13 ORY84150.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF448) Beta_elim_lyase PF01212.21 ORY84150.1 - 0.15 11.3 0.0 0.4 9.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase GAF_2 PF13185.6 ORY84151.1 - 4.3e-05 23.8 0.3 0.059 13.7 0.0 2.9 2 1 0 2 2 2 2 GAF domain GAF PF01590.26 ORY84151.1 - 0.0032 18.1 0.0 1.3 9.6 0.0 2.8 2 1 0 2 2 2 2 GAF domain GAF_3 PF13492.6 ORY84151.1 - 0.0057 17.0 0.7 5.3 7.4 0.2 3.3 2 1 0 2 2 2 2 GAF domain BCNT PF07572.12 ORY84152.1 - 1.2e-20 73.4 0.6 1.9e-20 72.7 0.1 1.6 2 0 0 2 2 2 1 Bucentaur or craniofacial development NUDE_C PF04880.13 ORY84152.1 - 5.9 7.3 7.0 12 6.3 7.0 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Scs3p PF10261.9 ORY84154.1 - 4.4e-53 180.3 8.8 2.9e-52 177.6 8.8 1.9 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF5486 PF17588.2 ORY84155.1 - 7.5 6.5 6.2 2.2 8.2 2.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5486) zf-4CXXC_R1 PF10497.9 ORY84156.1 - 1.2e-09 38.3 4.7 3e-09 37.0 4.7 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 BTD PF09270.10 ORY84157.1 - 0.055 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain FANC_SAP PF18081.1 ORY84160.1 - 0.014 15.6 1.0 0.37 11.0 0.3 2.9 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain F-box-like PF12937.7 ORY84161.1 - 0.00022 21.0 6.4 0.0004 20.2 6.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY84161.1 - 0.0023 17.8 4.1 0.0048 16.8 4.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY84161.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 F-box Tup_N PF08581.10 ORY84163.1 - 0.0003 21.0 1.3 0.0003 21.0 1.3 5.1 6 1 0 6 6 6 2 Tup N-terminal FlaG PF03646.15 ORY84163.1 - 0.083 13.1 0.1 0.083 13.1 0.1 3.9 3 2 3 6 6 6 0 FlaG protein DUF521 PF04412.13 ORY84163.1 - 0.087 11.5 0.1 0.2 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF521) NPV_P10 PF05531.12 ORY84163.1 - 7.7 7.1 15.9 12 6.5 0.8 4.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein WAPL PF07814.13 ORY84167.1 - 6.5e-26 91.0 1.6 6.3e-22 77.9 0.8 2.9 2 1 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin Imm49 PF15575.6 ORY84167.1 - 0.018 14.8 0.0 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 49 Abhydrolase_3 PF07859.13 ORY84169.1 - 9.9e-28 97.4 0.0 3.5e-19 69.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold AbiEii PF08843.11 ORY84170.1 - 0.15 12.0 0.1 0.42 10.5 0.1 1.8 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system EGF_MSP1_1 PF12946.7 ORY84171.1 - 0.028 14.5 2.0 0.054 13.6 2.0 1.6 1 0 0 1 1 1 0 MSP1 EGF domain 1 Rax2 PF12768.7 ORY84172.1 - 0.067 12.6 0.1 0.098 12.1 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF3246 PF11596.8 ORY84173.1 - 0.0026 17.2 16.7 0.0047 16.4 16.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Dicty_REP PF05086.12 ORY84173.1 - 0.32 8.9 0.6 0.41 8.6 0.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_pp85 PF04637.12 ORY84173.1 - 1 7.7 4.9 1.6 7.1 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Methyltransf_11 PF08241.12 ORY84174.1 - 5.1e-19 68.7 0.1 2.3e-18 66.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY84174.1 - 3.1e-17 63.0 0.1 1.1e-16 61.3 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY84174.1 - 1.1e-11 45.3 0.0 2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY84174.1 - 9.2e-11 41.8 0.0 1.6e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY84174.1 - 2.6e-05 24.1 0.0 3.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY84174.1 - 0.00028 20.3 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pro-kuma_activ PF09286.11 ORY84175.1 - 4.2e-41 140.6 0.1 6.8e-41 139.9 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 ORY84175.1 - 1.2e-07 31.3 2.9 2.2e-07 30.4 2.9 1.4 1 0 0 1 1 1 1 Subtilase family FAD-SLDH PF12318.8 ORY84177.1 - 0.0057 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Membrane bound FAD containing D-sorbitol dehydrogenase LRR_8 PF13855.6 ORY84177.1 - 0.79 9.5 4.5 15 5.4 0.3 3.5 4 0 0 4 4 4 0 Leucine rich repeat TauD PF02668.16 ORY84179.1 - 5.1e-46 157.6 0.1 6.2e-46 157.4 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ORY84179.1 - 0.031 13.4 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 CsiD SelB-wing_2 PF09106.11 ORY84179.1 - 0.077 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-C2H2 PF00096.26 ORY84180.1 - 0.087 13.3 0.9 0.16 12.5 0.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type RhoGEF PF00621.20 ORY84181.1 - 1.2e-14 54.9 0.0 1.9e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain Arylesterase PF01731.20 ORY84182.1 - 4.7e-06 26.7 0.0 8.7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Arylesterase SGL PF08450.12 ORY84182.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Cnd3 PF12719.7 ORY84182.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Arylesterase PF01731.20 ORY84183.1 - 0.0051 17.0 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 Arylesterase DER1 PF04511.15 ORY84184.1 - 8.6e-32 110.6 3.6 1e-31 110.4 3.6 1.0 1 0 0 1 1 1 1 Der1-like family ANAPC_CDC26 PF10471.9 ORY84186.1 - 0.00033 21.4 2.3 0.00084 20.1 2.3 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 SUZ PF12752.7 ORY84186.1 - 0.03 15.1 4.3 0.03 15.1 4.3 1.5 1 1 1 2 2 2 0 SUZ domain TauD PF02668.16 ORY84187.1 - 1.3e-45 156.3 0.1 1.6e-45 156.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family SelB-wing_2 PF09106.11 ORY84187.1 - 0.046 13.9 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Elongation factor SelB, winged helix CsiD PF08943.10 ORY84187.1 - 0.068 12.3 0.0 1 8.4 0.0 2.0 2 0 0 2 2 2 0 CsiD F-box-like PF12937.7 ORY84189.1 - 0.00047 20.0 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 ORY84191.1 - 3.7e-40 137.9 51.2 1.9e-39 135.6 28.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY84191.1 - 6.6e-09 35.1 21.4 7.1e-06 25.1 6.2 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter Cir_N PF10197.9 ORY84192.1 - 8.8 6.6 7.0 0.82 9.9 2.7 1.5 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR zf-MYND PF01753.18 ORY84193.1 - 1.2e-06 28.5 3.7 2.3e-06 27.6 3.7 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY84193.1 - 0.48 10.3 6.2 0.78 9.7 6.2 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 ORY84195.1 - 1.1e-08 35.0 9.3 1.1e-08 35.0 9.3 1.7 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 ORY84195.1 - 0.36 10.7 3.4 0.85 9.5 3.4 1.6 1 0 0 1 1 1 0 HIT zinc finger RhoGAP PF00620.27 ORY84622.1 - 7.5e-40 136.2 0.0 9.8e-40 135.9 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Bcr-Abl_Oligo PF09036.10 ORY84623.1 - 0.017 15.2 6.2 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Exonuc_VII_L PF02601.15 ORY84623.1 - 0.46 10.0 7.0 0.53 9.8 7.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0449 PF15136.6 ORY84623.1 - 1.2 9.6 12.5 0.68 10.4 7.8 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 WD40 PF00400.32 ORY84624.1 - 1.7e-40 136.2 21.9 8.4e-08 32.8 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY84624.1 - 0.00011 22.5 1.7 0.91 9.9 0.1 4.6 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY84624.1 - 0.00015 20.5 2.0 1.8 7.1 0.0 3.5 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Drf_GBD PF06371.13 ORY84625.1 - 7.1e-10 38.7 0.0 2.7e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain DUF1658 PF07871.11 ORY84625.1 - 0.046 13.7 9.1 2.6 8.1 2.7 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) GST_N PF02798.20 ORY84626.1 - 1.4e-17 63.8 0.1 4.5e-17 62.2 0.0 1.9 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY84626.1 - 3.5e-11 43.2 0.0 7.3e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY84626.1 - 4.9e-11 42.9 0.0 8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY84626.1 - 1.2e-10 41.4 0.1 2e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY84626.1 - 6.1e-09 35.8 0.1 1.1e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY84626.1 - 2.8e-08 33.9 0.0 4.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY84626.1 - 0.042 14.6 0.0 0.081 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Sulfotransfer_4 PF17784.1 ORY84627.1 - 2.5e-53 181.1 0.0 3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY84627.1 - 4.8e-08 33.7 0.6 3.9e-05 24.1 0.1 2.4 1 1 0 2 2 2 2 Sulfotransferase family AAA PF00004.29 ORY84628.1 - 1.4e-21 77.3 0.0 3.2e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY84628.1 - 0.02 15.3 1.5 9.4 6.6 0.0 3.1 2 1 1 3 3 3 0 AAA ATPase domain COX15-CtaA PF02628.15 ORY84629.1 - 0.00041 19.5 0.0 0.00054 19.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF3729 PF12526.8 ORY84629.1 - 0.095 14.3 1.9 0.16 13.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) MRP-S27 PF10037.9 ORY84629.1 - 0.1 11.4 3.7 0.13 11.1 3.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Phage_holin_3_1 PF05106.12 ORY84629.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Pec_lyase_N PF04431.13 ORY84629.1 - 0.14 12.5 1.5 0.22 11.8 0.2 2.1 2 0 0 2 2 2 0 Pectate lyase, N terminus ATP-synt_B PF00430.18 ORY84629.1 - 4.3 7.4 16.7 15 5.7 2.7 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) F-box-like PF12937.7 ORY84630.1 - 4.7e-08 32.8 0.1 1.4e-07 31.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY84630.1 - 0.0011 18.7 0.4 0.0011 18.7 0.4 2.6 2 1 0 2 2 2 1 F-box domain Sugar_tr PF00083.24 ORY84631.1 - 7.9e-126 420.5 27.7 9e-126 420.4 27.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY84631.1 - 3e-24 85.6 32.9 3.9e-15 55.6 10.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily RAI1 PF08652.11 ORY84632.1 - 3e-17 62.6 0.0 5.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Sugar_tr PF00083.24 ORY84632.1 - 0.15 10.9 2.3 1.5 7.6 0.1 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter CLASP_N PF12348.8 ORY84633.1 - 9.1e-11 41.7 0.0 1.1e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal DUF4745 PF15923.5 ORY84633.1 - 0.061 13.3 0.0 0.09 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) DUF2582 PF10771.9 ORY84634.1 - 0.0042 17.2 0.4 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix domain (DUF2582) DMSP_lyase PF16867.5 ORY84634.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Ssl1 PF04056.14 ORY84635.1 - 2.5e-67 226.4 0.0 5.2e-67 225.4 0.0 1.5 1 1 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 ORY84635.1 - 4.6e-11 42.8 19.7 7e-11 42.2 8.9 2.4 2 0 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 ORY84635.1 - 1.1e-10 42.1 0.0 2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 ORY84635.1 - 0.00092 18.8 5.0 0.035 13.6 4.6 2.3 2 1 0 2 2 2 1 Transcription factor Tfb4 IBR PF01485.21 ORY84635.1 - 0.021 15.0 2.2 0.021 15.0 2.2 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 ORY84635.1 - 0.28 11.2 20.4 3.5 7.7 5.3 3.1 2 1 0 2 2 2 0 Double zinc ribbon zf-AN1 PF01428.16 ORY84635.1 - 3.2 8.0 18.2 0.29 11.3 1.1 3.1 2 1 1 3 3 3 0 AN1-like Zinc finger zf_C2H2_10 PF18414.1 ORY84635.1 - 3.7 7.2 10.0 14 5.3 0.8 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger zf-HIT PF04438.16 ORY84635.1 - 9.5 6.2 26.7 0.17 11.8 2.7 3.5 4 0 0 4 4 4 0 HIT zinc finger THUMP PF02926.17 ORY84636.1 - 5.8e-05 23.2 0.0 0.00041 20.5 0.0 2.3 2 0 0 2 2 2 1 THUMP domain PP_M1 PF03012.14 ORY84636.1 - 0.067 12.7 0.8 0.1 12.1 0.2 1.5 2 0 0 2 2 2 0 Phosphoprotein DUF202 PF02656.15 ORY84638.1 - 3e-16 59.6 6.2 6.8e-16 58.5 4.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2530 PF10745.9 ORY84638.1 - 0.012 15.8 1.5 0.079 13.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF3180 PF11377.8 ORY84638.1 - 0.018 15.2 1.1 0.049 13.8 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3180) MscS_TM PF12794.7 ORY84638.1 - 1.3 7.8 7.4 3 6.6 0.1 2.3 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 Memo PF01875.17 ORY84639.1 - 2.4e-72 243.4 0.0 2.8e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein EP400_N PF15790.5 ORY84639.1 - 0.022 13.6 0.6 0.048 12.5 0.4 1.7 1 1 1 2 2 2 0 E1A-binding protein p400, N-terminal Aldo_ket_red PF00248.21 ORY84640.1 - 5.3e-36 124.3 0.0 1.6e-34 119.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family CENP-Q PF13094.6 ORY84641.1 - 3.5e-15 56.6 11.5 3.5e-15 56.6 11.5 2.5 1 1 1 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit FAM176 PF14851.6 ORY84641.1 - 1 9.0 11.7 0.61 9.7 1.2 2.8 3 0 0 3 3 3 0 FAM176 family F-box-like PF12937.7 ORY84642.1 - 0.00012 21.9 1.2 0.0004 20.2 1.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY84642.1 - 0.0096 15.8 0.7 0.18 11.7 0.2 2.7 2 0 0 2 2 2 1 F-box domain DUF5375 PF17345.2 ORY84642.1 - 0.11 12.4 0.2 0.26 11.2 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5375) LRR_4 PF12799.7 ORY84643.1 - 9.3e-05 22.7 1.6 0.039 14.4 0.1 3.8 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) Pol_alpha_B_N PF08418.10 ORY84644.1 - 0.39 10.6 9.2 0.56 10.1 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CDC27 PF09507.10 ORY84644.1 - 0.86 8.9 9.6 1.2 8.4 9.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1917 PF08939.10 ORY84645.1 - 1.1e-25 91.1 0.0 2.5e-25 89.9 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) ERG4_ERG24 PF01222.17 ORY84648.1 - 2.1e-144 481.5 5.8 2.4e-144 481.3 5.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY84648.1 - 1.3e-08 34.7 0.3 3e-08 33.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ORY84648.1 - 0.00038 20.8 3.2 0.0013 19.1 0.0 3.2 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 ORY84648.1 - 0.039 14.4 0.7 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ribosomal_L30_N PF08079.12 ORY84649.1 - 3.4e-19 68.9 7.1 6.6e-19 67.9 7.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 ORY84649.1 - 6.9e-18 64.3 1.4 1.3e-17 63.3 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e SET PF00856.28 ORY84650.1 - 0.039 14.3 0.0 0.069 13.5 0.0 1.3 1 1 0 1 1 1 0 SET domain F-box PF00646.33 ORY84651.1 - 2.2e-07 30.6 1.6 4.9e-07 29.5 1.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY84651.1 - 0.0028 17.5 0.3 0.0093 15.8 0.5 1.8 2 0 0 2 2 2 1 F-box-like zf-3CxxC_2 PF17180.4 ORY84651.1 - 0.026 15.2 0.3 0.16 12.7 0.3 2.4 1 0 0 1 1 1 0 Zinc-binding domain DEK_C PF08766.11 ORY84651.1 - 0.29 11.1 6.1 0.57 10.2 0.2 3.2 3 0 0 3 3 3 0 DEK C terminal domain RXLR PF16810.5 ORY84651.1 - 0.91 10.0 6.8 1.1 9.7 1.6 2.5 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity FA_hydroxylase PF04116.13 ORY84652.1 - 4.1e-24 85.4 14.3 4.1e-24 85.4 14.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MAGUK_N_PEST PF10608.9 ORY84654.1 - 0.049 14.1 0.1 0.096 13.1 0.1 1.4 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK PRIMA1 PF16101.5 ORY84654.1 - 7.7 6.6 7.6 9.4 6.3 0.2 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SET PF00856.28 ORY84655.1 - 1.7e-13 51.3 0.0 4.4e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 ORY84655.1 - 9.5e-12 45.7 0.6 2.2e-11 44.6 0.6 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Transp_cyt_pur PF02133.15 ORY84657.1 - 4.3e-85 286.1 41.0 5.3e-85 285.8 41.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin F-box-like PF12937.7 ORY84658.1 - 0.00073 19.4 0.4 0.0016 18.3 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY84658.1 - 0.0024 17.7 2.0 0.0067 16.3 2.0 1.8 1 0 0 1 1 1 1 F-box domain Plasmodium_Vir PF05795.11 ORY84658.1 - 3.1 7.1 4.1 7.1 5.9 4.1 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Paf1 PF03985.13 ORY84658.1 - 4.7 6.1 15.2 13 4.7 15.2 1.8 1 0 0 1 1 1 0 Paf1 Ctr PF04145.15 ORY84659.1 - 2.4e-21 76.9 0.2 2.8e-21 76.7 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Pro_racemase PF05544.11 ORY84661.1 - 3.9e-59 200.3 0.0 5.2e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Proline racemase Hexapep PF00132.24 ORY84662.1 - 3.3e-10 39.3 5.3 2e-06 27.3 4.7 3.1 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY84662.1 - 2.2e-07 31.4 0.1 1e-06 29.2 0.1 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 ORY84662.1 - 5.1e-06 24.9 2.7 9.6e-06 24.0 2.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 ORY84662.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.6 1 1 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.6 ORY84662.1 - 0.019 14.7 10.2 12 5.7 10.5 2.7 1 1 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 ORY84662.1 - 0.087 12.7 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase Pkinase PF00069.25 ORY84663.1 - 2.4e-44 151.7 0.0 5.3e-34 117.8 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY84663.1 - 3.8e-16 59.2 0.0 2.4e-12 46.7 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ORY84663.1 - 0.00023 20.6 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY84663.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY84663.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY84663.1 - 0.0038 16.1 0.0 0.0052 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY84663.1 - 0.027 13.4 0.0 0.083 11.8 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Choline_kinase PF01633.20 ORY84663.1 - 0.23 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HSF_DNA-bind PF00447.17 ORY84665.1 - 4e-18 65.8 0.0 4.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding LRR_4 PF12799.7 ORY84666.1 - 1.7e-23 82.3 42.1 0.00012 22.3 8.6 9.7 8 2 2 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY84666.1 - 9e-18 63.8 48.0 9.2e-05 22.1 14.0 9.7 7 3 2 9 9 9 6 Leucine rich repeat LRR_6 PF13516.6 ORY84666.1 - 2.4e-09 36.5 36.3 0.25 11.5 0.2 12.1 13 0 0 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.33 ORY84666.1 - 3.1e-05 23.9 34.6 1.1 10.1 0.1 10.9 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_9 PF14580.6 ORY84666.1 - 0.08 12.4 6.3 2.1 7.8 0.4 4.7 5 1 0 6 6 6 0 Leucine-rich repeat DUF809 PF05663.11 ORY84666.1 - 1.2 9.3 6.2 2.8 8.1 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Glyco_transf_49 PF13896.6 ORY84667.1 - 3.2e-14 53.0 0.1 1.5e-12 47.5 0.1 2.8 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan DDHD PF02862.17 ORY84668.1 - 1e-31 110.8 0.0 6.7e-31 108.2 0.0 2.2 2 0 0 2 2 2 1 DDHD domain DUF1077 PF06417.12 ORY84669.1 - 1.7e-38 131.2 0.6 4.1e-38 130.0 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1077) Glutaredoxin PF00462.24 ORY84670.1 - 1.7e-17 63.3 0.0 4.1e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 ORY84670.1 - 1.8e-08 34.3 0.0 3.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 ORY84670.1 - 0.008 16.1 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE SH3BGR PF04908.15 ORY84670.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ribosomal_60s PF00428.19 ORY84670.1 - 0.051 14.2 2.2 0.097 13.3 2.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DIM1 PF02966.16 ORY84670.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_2 PF13098.6 ORY84670.1 - 0.12 12.8 0.0 1.4 9.4 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like domain CDC27 PF09507.10 ORY84671.1 - 2.1e-21 76.9 40.7 1.3e-19 70.9 0.1 3.0 1 1 2 3 3 3 3 DNA polymerase subunit Cdc27 Abhydrolase_2 PF02230.16 ORY84672.1 - 5.9e-10 39.3 0.0 8.3e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Amidohydro_2 PF04909.14 ORY84673.1 - 1.2e-23 84.3 0.1 3.3e-22 79.6 0.1 2.6 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 ORY84673.1 - 0.014 14.8 0.0 0.056 12.8 0.0 1.8 2 0 0 2 2 2 0 TatD related DNase Chromo PF00385.24 ORY84674.1 - 1.5e-06 28.0 5.3 4.6e-06 26.5 5.3 1.8 1 1 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHY PF00360.20 ORY84674.1 - 0.0059 15.9 0.5 0.0076 15.6 0.5 1.2 1 0 0 1 1 1 1 Phytochrome region YTH PF04146.15 ORY84676.1 - 3e-48 163.9 0.0 4.2e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 ORY84676.1 - 8.8e-05 22.3 0.0 0.0031 17.3 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos PF03372.23 ORY84677.1 - 1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Gtr1_RagA PF04670.12 ORY84678.1 - 2e-54 184.4 0.2 2.6e-54 184.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 ORY84678.1 - 3.9e-06 26.4 0.0 5.5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY84678.1 - 0.0033 17.5 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORY84678.1 - 0.015 14.5 0.1 1 8.5 0.0 2.7 1 1 1 3 3 3 0 G-protein alpha subunit Meckelin PF09773.9 ORY84678.1 - 0.036 12.2 0.4 0.045 11.9 0.4 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Meth_synt_2 PF01717.18 ORY84679.1 - 6.1e-17 61.9 0.0 5.6e-16 58.7 0.0 2.0 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY84679.1 - 2.3e-05 24.1 0.0 0.019 14.5 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Zn_clus PF00172.18 ORY84680.1 - 2.2e-05 24.5 12.9 3.5e-05 23.8 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY84680.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 ORY84681.1 - 1.5e-119 399.7 35.7 2.1e-119 399.2 35.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Collectrin PF16959.5 ORY84682.1 - 0.25 11.1 0.1 0.41 10.4 0.1 1.3 1 0 0 1 1 1 0 Renal amino acid transporter Utp14 PF04615.13 ORY84682.1 - 0.4 9.2 7.4 0.49 8.9 7.4 1.1 1 0 0 1 1 1 0 Utp14 protein SPX PF03105.19 ORY84682.1 - 6.3 6.6 24.9 0.092 12.6 15.9 2.1 2 0 0 2 2 2 0 SPX domain Whi5 PF08528.11 ORY84683.1 - 5e-06 26.0 0.0 9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Ammonium_transp PF00909.21 ORY84684.1 - 1.9e-116 389.1 26.3 2.1e-116 388.9 26.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family RTX PF02382.15 ORY84684.1 - 1.3 8.6 4.1 2.2 7.9 4.1 1.3 1 0 0 1 1 1 0 N-terminal domain in RTX protein Ammonium_transp PF00909.21 ORY84685.1 - 1.5e-113 379.6 30.7 1.7e-113 379.3 30.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PAP2_3 PF14378.6 ORY84686.1 - 4.9e-24 85.1 11.3 4.9e-24 85.1 11.3 2.1 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 ORY84686.1 - 2.1e-08 34.0 6.3 2.1e-08 34.0 6.3 2.2 2 2 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 ORY84686.1 - 2.1 8.9 11.3 0.12 12.9 4.4 2.5 2 1 2 4 4 4 0 PAP2 superfamily C-terminal zf-MYND PF01753.18 ORY84687.1 - 1.8e-09 37.5 9.8 3.7e-09 36.5 9.8 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY84687.1 - 0.26 11.6 8.3 0.59 10.5 8.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MIP PF00230.20 ORY84689.1 - 2.6e-47 161.4 9.8 3e-47 161.2 9.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein ABC2_membrane PF01061.24 ORY84689.1 - 1.3 8.4 11.1 0.25 10.7 7.8 1.4 2 0 0 2 2 2 0 ABC-2 type transporter Prefoldin PF02996.17 ORY84691.1 - 3.7e-13 49.5 0.8 4e-13 49.3 0.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin PF00261.20 ORY84691.1 - 0.0016 17.9 0.8 0.0027 17.1 0.8 1.3 1 0 0 1 1 1 1 Tropomyosin Prefoldin_2 PF01920.20 ORY84691.1 - 0.023 14.6 4.0 0.055 13.4 1.1 2.0 2 0 0 2 2 2 0 Prefoldin subunit Spectrin PF00435.21 ORY84691.1 - 0.035 14.6 1.2 0.43 11.1 0.1 2.1 2 0 0 2 2 2 0 Spectrin repeat SlyX PF04102.12 ORY84691.1 - 0.093 13.4 4.0 1.5 9.5 0.2 2.2 2 0 0 2 2 2 0 SlyX DivIC PF04977.15 ORY84691.1 - 0.26 11.1 3.1 0.18 11.6 0.4 1.9 2 0 0 2 2 2 0 Septum formation initiator BRE1 PF08647.11 ORY84691.1 - 1.4 9.0 5.8 5.6 7.1 1.3 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase SYS1 PF09801.9 ORY84692.1 - 1.5e-25 90.0 5.8 8.3e-18 64.9 2.9 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network MFS_1 PF07690.16 ORY84693.1 - 2.8e-30 105.5 46.1 5.9e-27 94.5 45.1 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY84693.1 - 1.9e-11 43.1 20.8 5.2e-10 38.4 20.8 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 ORY84693.1 - 1.7e-06 28.0 8.0 3.1e-06 27.2 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY84693.1 - 9.5e-06 24.8 0.0 1.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHFR_1 PF00186.19 ORY84695.1 - 9.5e-25 87.2 0.0 1.7e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrofolate reductase F-box-like PF12937.7 ORY84698.1 - 4.9e-07 29.5 2.1 9.9e-07 28.6 2.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY84698.1 - 2.4e-05 24.1 1.6 5.7e-05 22.9 1.6 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY84698.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 F-box FAM91_C PF14648.6 ORY84698.1 - 0.056 12.3 0.1 0.076 11.8 0.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus HSP70 PF00012.20 ORY84699.1 - 2.4e-155 518.1 0.1 3.5e-155 517.6 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY84699.1 - 4.7e-09 35.5 0.0 7.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 ORY84699.1 - 0.089 11.4 0.0 9.9 4.6 0.0 2.6 3 0 0 3 3 3 0 Actin GFO_IDH_MocA PF01408.22 ORY84700.1 - 3.2e-18 66.7 0.2 5.7e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY84700.1 - 3.4e-15 56.1 0.0 7.5e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 ORY84700.1 - 0.0069 16.8 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain FA_hydroxylase PF04116.13 ORY84701.1 - 4.4e-23 82.1 25.7 1.9e-22 80.0 21.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily PetL PF05115.14 ORY84701.1 - 1 9.4 6.5 2.6 8.1 6.5 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) PTPlike_phytase PF14566.6 ORY84702.1 - 3.3e-123 407.4 0.0 4.2e-41 140.7 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 ORY84702.1 - 0.0012 18.6 0.0 0.019 14.8 0.0 2.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY84702.1 - 0.0055 16.3 0.1 1.1 8.8 0.0 2.6 3 0 0 3 3 3 2 Protein-tyrosine phosphatase ANT PF03374.14 ORY84702.1 - 0.18 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain ATP-synt_C PF00137.21 ORY84703.1 - 5.2e-23 81.2 25.1 2e-13 50.5 9.2 3.1 3 1 0 3 3 3 2 ATP synthase subunit C zf-MYND PF01753.18 ORY84704.1 - 6.9e-11 42.0 10.0 1.7e-10 40.8 10.0 1.7 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY84704.1 - 6.5 6.7 9.6 15 5.6 9.6 1.7 1 0 0 1 1 1 0 HIT zinc finger Fe_hyd_lg_C PF02906.14 ORY84705.1 - 7.5e-59 199.3 0.0 2.3e-58 197.8 0.0 1.8 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain ADH_zinc_N PF00107.26 ORY84706.1 - 4.2e-20 72.0 0.3 7e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY84706.1 - 2.6e-11 44.7 0.0 5.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY84706.1 - 0.0074 16.2 0.0 0.037 13.9 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ORY84706.1 - 0.023 14.2 0.1 0.033 13.7 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ACP_syn_III_C PF08541.10 ORY84706.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal F-box PF00646.33 ORY84707.1 - 0.00015 21.5 1.3 0.00034 20.4 1.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY84707.1 - 0.00066 19.5 4.4 0.0016 18.3 4.4 1.8 1 1 0 1 1 1 1 F-box-like ATP-synt_E PF05680.12 ORY84707.1 - 0.026 14.9 1.1 0.037 14.4 1.1 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF1543 PF07566.12 ORY84707.1 - 0.18 11.5 0.2 0.42 10.4 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) PLA2_B PF01735.18 ORY84708.1 - 4.8e-24 84.6 0.0 1.7e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Lysophospholipase catalytic domain SNARE PF05739.19 ORY84709.1 - 3.6e-10 39.7 0.1 9.4e-10 38.3 0.1 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 ORY84709.1 - 0.0036 17.0 3.7 0.015 15.0 3.7 1.9 1 1 0 1 1 1 1 Syntaxin DUF5383 PF17355.2 ORY84709.1 - 0.3 11.4 1.3 4.3 7.7 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) MIF4G PF02854.19 ORY84710.1 - 2e-53 181.2 0.0 8.4e-33 113.8 0.0 3.9 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 ORY84710.1 - 4e-29 102.1 10.3 4e-29 102.1 10.3 2.3 2 0 0 2 2 2 1 Up-frameshift suppressor 2 zf-CCCH_4 PF18044.1 ORY84711.1 - 3.2e-05 23.6 13.8 0.005 16.6 0.7 3.3 2 1 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY84711.1 - 3.2e-05 23.8 16.0 0.0012 18.8 2.9 3.4 2 1 2 4 4 4 3 Zinc finger domain zf-CCCH PF00642.24 ORY84711.1 - 5.2e-05 23.0 9.6 0.0061 16.4 0.8 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY84711.1 - 0.041 14.6 0.5 0.041 14.6 0.5 2.5 2 1 0 2 2 2 0 Torus domain PID PF00640.23 ORY84711.1 - 0.089 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) Med21 PF11221.8 ORY84711.1 - 0.22 11.8 6.5 0.42 10.9 0.3 2.3 2 0 0 2 2 2 0 Subunit 21 of Mediator complex zf-CCCH_2 PF14608.6 ORY84711.1 - 5.6 7.6 10.9 17 6.1 3.2 3.5 3 1 1 4 4 4 0 RNA-binding, Nab2-type zinc finger Zip PF02535.22 ORY84712.1 - 5.9e-59 200.0 12.5 6.7e-59 199.8 12.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter CTP_transf_1 PF01148.20 ORY84714.1 - 3.6e-69 233.5 16.1 1.2e-63 215.4 9.5 2.1 2 0 0 2 2 2 2 Cytidylyltransferase family DUF433 PF04255.14 ORY84714.1 - 0.19 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) FAD_binding_4 PF01565.23 ORY84716.1 - 2.4e-28 98.6 3.7 4e-28 97.9 3.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY84716.1 - 9.1e-13 48.1 0.0 1.9e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like COX4 PF02936.14 ORY84716.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV ADH_zinc_N PF00107.26 ORY84717.1 - 1.3e-28 99.6 0.5 2.8e-28 98.5 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY84717.1 - 1.8e-08 35.5 0.0 2.7e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY84717.1 - 2.3e-05 24.2 0.0 0.00037 20.3 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain VTC PF09359.10 ORY84719.1 - 1.2e-91 307.0 0.0 1.9e-91 306.3 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 ORY84719.1 - 9.2e-18 65.3 14.8 4.5e-07 30.1 0.0 4.4 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.15 ORY84719.1 - 3.2e-11 43.5 0.4 5.7e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF202) polyprenyl_synt PF00348.17 ORY84720.1 - 5.4e-97 323.8 0.1 6.4e-97 323.6 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RasGAP PF00616.19 ORY84722.1 - 4.4e-52 176.8 0.0 1.4e-51 175.1 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORY84722.1 - 2.1e-36 125.1 0.1 2.1e-36 125.1 0.1 1.9 2 0 0 2 2 2 1 RasGAP C-terminus PheRS_DBD2 PF18554.1 ORY84722.1 - 0.0065 16.4 0.3 0.032 14.2 0.3 2.3 1 0 0 1 1 1 1 PheRS DNA binding domain 2 Cob_adeno_trans PF01923.18 ORY84722.1 - 0.092 12.9 3.6 2.5 8.2 0.7 2.7 2 0 0 2 2 2 0 Cobalamin adenosyltransferase YabA PF06156.13 ORY84722.1 - 2.9 8.6 6.9 5.5 7.7 1.3 3.2 3 0 0 3 3 3 0 Initiation control protein YabA ASH PF15780.5 ORY84723.1 - 7.2e-15 55.0 2.6 0.1 12.8 0.0 8.5 8 1 1 10 10 10 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 ORY84723.1 - 3.2e-08 33.6 0.5 0.0032 17.6 0.0 5.4 6 0 0 6 6 6 2 Flagellar-associated PapD-like DUF1573 PF07610.11 ORY84723.1 - 3.4e-06 27.0 0.1 0.41 10.7 0.0 5.2 5 0 0 5 5 5 2 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 ORY84723.1 - 5e-05 23.5 0.4 9 6.6 0.0 6.2 7 0 0 7 7 7 1 Transmembrane protein 131-like Phostensin PF13914.6 ORY84723.1 - 0.19 12.3 2.8 0.76 10.4 0.0 3.2 3 0 0 3 3 3 0 Phostensin PP1-binding and SH3-binding region IMS PF00817.20 ORY84724.1 - 1.8e-40 138.4 0.4 2.2e-39 134.9 0.1 2.4 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ORY84724.1 - 1e-12 48.8 1.2 2.7e-12 47.4 0.2 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 ORY84724.1 - 0.0039 17.4 0.0 0.0087 16.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_4 PF13894.6 ORY84724.1 - 0.0076 17.0 0.1 0.02 15.7 0.1 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 ORY84724.1 - 0.033 14.7 0.2 0.069 13.6 0.2 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2HE PF16278.5 ORY84724.1 - 0.049 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger cobW PF02492.19 ORY84724.1 - 0.11 12.0 0.0 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FAD_binding_3 PF01494.19 ORY84725.1 - 3.5e-60 204.1 0.1 1e-43 150.0 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 ORY84725.1 - 1.7e-32 112.7 0.0 3.9e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 ORY84725.1 - 0.00013 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY84725.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ORY84725.1 - 0.033 13.2 0.1 0.047 12.7 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 ORY84725.1 - 0.06 12.6 0.2 0.15 11.3 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY84725.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ferritin_2 PF13668.6 ORY84726.1 - 5e-42 143.3 3.9 7.9e-42 142.7 3.9 1.3 1 0 0 1 1 1 1 Ferritin-like domain F-box-like PF12937.7 ORY84727.1 - 9e-08 31.9 0.2 1.7e-07 31.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY84727.1 - 9.3e-05 22.2 0.0 0.00022 21.0 0.0 1.7 1 1 0 1 1 1 1 F-box domain GATA PF00320.27 ORY84728.1 - 1.1e-14 53.7 3.8 2.4e-14 52.6 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 ORY84728.1 - 0.052 13.6 0.5 0.19 11.8 0.5 1.9 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 ORY84728.1 - 0.85 9.8 2.7 2.7 8.2 0.4 2.6 3 0 0 3 3 3 0 Zinc ribbon domain Methyltransf_16 PF10294.9 ORY84729.1 - 1.4e-17 64.0 0.0 3.8e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase DnaJ_C PF01556.18 ORY84730.1 - 6.3e-39 133.4 0.1 8.1e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY84730.1 - 4e-26 90.9 1.8 7e-26 90.1 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain Forkhead_N PF08430.12 ORY84730.1 - 8.8 6.9 11.9 16 6.1 11.9 1.4 1 0 0 1 1 1 0 Forkhead N-terminal region Pkinase PF00069.25 ORY84731.1 - 2e-12 47.1 0.0 2.6e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY84731.1 - 6.1e-07 29.6 0.5 1.1e-06 28.8 0.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY84731.1 - 7.3e-05 22.2 0.2 0.0001 21.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 ORY84731.1 - 0.00013 21.4 0.3 0.00037 19.9 0.3 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY84731.1 - 0.00084 19.0 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 ORY84731.1 - 0.0035 16.2 0.1 0.004 16.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY84731.1 - 0.0092 15.3 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 ORY84731.1 - 0.012 15.2 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 ORY84731.1 - 0.053 12.6 0.2 0.068 12.2 0.2 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 PIP49_C PF12260.8 ORY84731.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RNB PF00773.19 ORY84732.1 - 3.3e-93 312.6 0.0 4.4e-93 312.2 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 ORY84732.1 - 1.5e-22 79.3 0.2 2.7e-22 78.5 0.2 1.5 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 ORY84732.1 - 3.4e-20 72.3 0.2 9.9e-19 67.5 0.0 2.5 1 1 1 2 2 2 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 ORY84732.1 - 7.3e-16 58.0 0.0 1.8e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 ORY84732.1 - 4.1e-09 36.8 0.0 8.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 ORY84732.1 - 1.7e-06 28.1 1.1 0.0022 18.1 0.0 4.3 5 0 0 5 5 5 1 Cold shock domain F-box PF00646.33 ORY84733.1 - 6.7e-06 25.8 1.0 1.9e-05 24.4 1.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY84733.1 - 0.00016 21.5 0.3 0.00038 20.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY84733.1 - 0.03 14.2 0.4 0.15 11.9 0.1 2.1 2 0 0 2 2 2 0 F-box ADH_N PF08240.12 ORY84734.1 - 1.1e-20 73.6 6.2 2.1e-20 72.6 6.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY84734.1 - 5e-06 26.5 0.0 9.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fas_alpha_ACP PF18325.1 ORY84735.1 - 7.4e-72 241.0 0.0 1.5e-71 240.0 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 ORY84735.1 - 2.6e-71 239.5 0.0 4.8e-71 238.6 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 ORY84735.1 - 4.9e-69 233.3 0.0 1e-68 232.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 ORY84735.1 - 2.5e-25 89.5 0.5 5.1e-25 88.5 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MaoC_dehydratas PF01575.19 ORY84735.1 - 8.2e-23 80.3 0.0 2.2e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_meander PF17951.1 ORY84735.1 - 8.6e-16 58.1 0.0 1.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain Ketoacyl-synt_C PF02801.22 ORY84735.1 - 8.9e-15 54.8 0.0 4.1e-14 52.6 0.0 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydrat_N PF13452.6 ORY84735.1 - 1.4e-13 51.1 0.0 4.4e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase adh_short PF00106.25 ORY84735.1 - 1.3e-05 24.8 0.0 2.8e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY84735.1 - 0.0018 17.9 0.0 0.006 16.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY84735.1 - 0.0034 17.3 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 KR domain Thiolase_N PF00108.23 ORY84735.1 - 0.12 11.7 0.3 0.24 10.7 0.3 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Msg2_C PF12373.8 ORY84735.1 - 1.2 8.7 6.2 12 5.4 0.5 3.5 3 0 0 3 3 3 0 Major surface glycoprotein 2 C terminal PS_Dcarbxylase PF02666.15 ORY84736.1 - 1.1e-53 181.8 0.0 1.9e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 ORY84736.1 - 2.5e-36 124.1 0.0 3.6e-18 65.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.6 ORY84736.1 - 0.13 12.7 0.2 0.38 11.2 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair TFIIA PF03153.13 ORY84737.1 - 0.017 15.1 10.1 0.03 14.4 10.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G-patch PF01585.23 ORY84738.1 - 0.35 10.8 1.7 0.7 9.8 0.7 2.0 2 1 0 2 2 2 0 G-patch domain DUF2457 PF10446.9 ORY84738.1 - 0.94 8.5 3.7 0.98 8.5 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MS_channel PF00924.18 ORY84739.1 - 1.4e-22 80.3 2.8 2.8e-22 79.3 2.8 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel TRAPPC-Trs85 PF12739.7 ORY84739.1 - 0.15 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Ribosomal_60s PF00428.19 ORY84739.1 - 6.3 7.5 6.1 0.54 10.9 0.2 2.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein ADH_N PF08240.12 ORY84740.1 - 3.7e-20 71.8 6.0 7.2e-20 70.9 6.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY84740.1 - 1.6e-06 28.1 0.0 3.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase F-box PF00646.33 ORY84741.1 - 5.3e-05 23.0 1.7 5.3e-05 23.0 1.7 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY84741.1 - 0.018 14.9 0.5 0.043 13.7 0.5 1.6 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 ORY84741.1 - 0.12 12.2 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 F-box DUF5630 PF18632.1 ORY84741.1 - 0.15 11.4 0.0 3.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5630) adh_short PF00106.25 ORY84742.1 - 1.4e-12 47.5 0.0 3.8e-10 39.6 0.0 3.0 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY84742.1 - 7.4e-09 35.8 0.0 1.3e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 ORY84742.1 - 5.1e-08 32.8 0.0 6.9e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY84742.1 - 0.0003 20.3 0.0 0.0005 19.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 ORY84744.1 - 1.5e-86 290.8 0.0 2.4e-86 290.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORY84744.1 - 1.2e-43 149.0 0.0 2.3e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 ORY84744.1 - 0.0031 16.3 0.1 0.005 15.6 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 ORY84744.1 - 0.0059 15.9 0.2 0.03 13.5 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY84744.1 - 0.036 13.3 0.1 0.077 12.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 ORY84744.1 - 0.045 12.6 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_2 PF00890.24 ORY84744.1 - 0.046 12.8 0.1 0.09 11.8 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Alph_Pro_TM PF09608.10 ORY84744.1 - 0.046 13.5 0.0 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) AlaDh_PNT_C PF01262.21 ORY84744.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 ORY84744.1 - 0.094 13.0 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY84744.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ORY84744.1 - 0.18 11.1 0.2 0.26 10.6 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase PEX11 PF05648.14 ORY84745.1 - 3e-19 69.4 0.1 3.6e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Proteasome PF00227.26 ORY84746.1 - 1e-32 113.2 0.2 1.4e-32 112.7 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Cys_Met_Meta_PP PF01053.20 ORY85287.1 - 8.3e-144 478.8 0.0 9.4e-144 478.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY85287.1 - 6.1e-11 42.1 0.1 9.8e-11 41.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY85287.1 - 5.6e-09 35.8 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORY85287.1 - 1.8e-06 27.2 0.1 3.2e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 ORY85287.1 - 0.001 17.7 0.1 0.0013 17.3 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 ORY85287.1 - 0.031 13.6 0.0 0.087 12.1 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Thaumatin PF00314.17 ORY85288.1 - 1.5e-43 148.9 12.0 1.9e-43 148.6 12.0 1.1 1 0 0 1 1 1 1 Thaumatin family MbtH PF03621.13 ORY85288.1 - 0.3 10.6 1.7 3 7.3 0.1 2.5 2 0 0 2 2 2 0 MbtH-like protein NRDE-2 PF08424.10 ORY85289.1 - 3.2e-93 312.4 0.0 2.7e-90 302.8 0.0 3.1 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 ORY85289.1 - 0.00017 22.1 27.5 1.8 9.6 0.1 8.4 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY85289.1 - 0.00024 21.5 8.0 0.0064 17.0 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY85289.1 - 0.0061 16.5 1.4 3.5 7.6 0.0 4.1 4 0 0 4 4 4 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 ORY85289.1 - 0.05 13.7 4.7 9.4 6.6 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Suf PF05843.14 ORY85289.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) TPR_11 PF13414.6 ORY85289.1 - 0.19 11.4 0.3 0.62 9.8 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_15 PF13429.6 ORY85289.1 - 0.2 10.9 6.8 2.2 7.4 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY85289.1 - 0.26 12.0 10.8 13 6.5 0.3 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY85289.1 - 0.33 11.3 0.1 0.33 11.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY85289.1 - 0.38 10.7 6.3 0.067 13.1 0.4 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apt1 PF10351.9 ORY85289.1 - 0.57 9.0 4.0 0.85 8.4 4.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TTL PF03133.15 ORY85290.1 - 1.1e-48 165.9 0.0 1.7e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORY85290.1 - 0.088 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 ORY85290.1 - 0.094 12.8 0.0 3.5 7.7 0.0 2.5 3 0 0 3 3 3 0 ATP-grasp domain AMP-binding PF00501.28 ORY85291.1 - 1.8e-74 250.9 0.0 7.2e-74 248.9 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY85291.1 - 4.2e-09 37.3 0.1 9.2e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD-oxidase_C PF02913.19 ORY85292.1 - 2e-57 194.7 0.0 2.9e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY85292.1 - 7.7e-31 106.7 0.1 1.3e-30 105.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain PCI PF01399.27 ORY85294.1 - 1.8e-09 38.1 2.6 3.1e-09 37.3 0.0 2.8 3 1 1 4 4 4 1 PCI domain PseudoU_synth_2 PF00849.22 ORY85295.1 - 3.6e-27 95.4 0.0 4.6e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M36 PF02128.15 ORY85296.1 - 6.3e-154 512.6 0.5 8.4e-154 512.2 0.5 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 ORY85296.1 - 0.00051 19.8 0.2 0.00091 19.0 0.2 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 ORY85296.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain MFS_1 PF07690.16 ORY85297.1 - 7.1e-38 130.4 21.8 7.1e-38 130.4 21.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MPC PF03650.13 ORY85297.1 - 0.76 9.9 6.3 0.47 10.6 0.3 3.0 3 1 1 4 4 4 0 Mitochondrial pyruvate carriers DUF1770 PF08589.10 ORY85298.1 - 1.5e-05 25.8 1.2 2.6e-05 25.1 0.9 1.5 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) HABP4_PAI-RBP1 PF04774.15 ORY85299.1 - 0.0028 18.5 6.2 0.0028 18.5 6.2 2.0 2 0 0 2 2 2 1 Hyaluronan / mRNA binding family COPI_C PF06957.11 ORY85299.1 - 0.14 10.9 0.5 0.2 10.4 0.5 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ion_trans PF00520.31 ORY85301.1 - 5.2e-126 418.9 91.8 4e-37 127.8 8.3 5.1 5 0 0 5 5 5 5 Ion transport protein Peptidase_M18 PF02127.15 ORY85302.1 - 3.5e-143 477.5 0.0 4e-143 477.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ORY85302.1 - 0.0021 17.1 0.0 0.015 14.4 0.0 2.0 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase ICMT PF04140.14 ORY85303.1 - 4.8e-26 91.0 0.9 7.7e-26 90.3 0.3 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORY85303.1 - 1.5e-11 44.6 1.7 1.5e-11 44.6 1.7 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 ORY85303.1 - 0.00058 19.4 2.3 0.0014 18.1 0.2 2.1 2 0 0 2 2 2 1 NnrU protein DUF1295 PF06966.12 ORY85303.1 - 0.00066 19.3 0.4 0.0011 18.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DEAD PF00270.29 ORY85304.1 - 3.4e-34 118.1 0.2 5.7e-34 117.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY85304.1 - 1.6e-28 99.2 0.5 4e-28 98.0 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY85304.1 - 0.00018 21.6 0.0 0.00058 19.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ArAE_2_N PF10337.9 ORY85305.1 - 0.00021 20.5 0.4 0.049 12.7 0.0 2.3 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 ORY85305.1 - 0.0037 16.2 8.4 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC_2 PF13515.6 ORY85305.1 - 0.007 16.5 8.9 0.007 16.5 8.9 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORY85305.1 - 0.011 14.4 12.1 0.014 14.0 0.6 2.8 3 0 0 3 3 3 0 Fusaric acid resistance protein family Tubulin PF00091.25 ORY85308.1 - 2.6e-58 197.5 0.0 5.9e-58 196.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY85308.1 - 1.5e-40 138.3 0.1 2.2e-40 137.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 ORY85308.1 - 0.01 15.1 0.1 0.027 13.7 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Stig1 PF04885.13 ORY85309.1 - 0.81 10.2 76.4 0.11 13.0 8.5 6.7 3 3 2 6 6 6 0 Stigma-specific protein, Stig1 PAF-AH_p_II PF03403.13 ORY85310.1 - 2.6e-53 180.9 0.0 3e-48 164.2 0.0 2.8 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORY85310.1 - 2.6e-06 26.5 0.0 1.6e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 ORY85310.1 - 0.00013 21.3 0.0 0.29 10.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ORY85310.1 - 0.00016 20.8 0.0 0.02 13.9 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase Abhydrolase_6 PF12697.7 ORY85310.1 - 0.0002 22.0 0.9 0.0002 22.0 0.9 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY85310.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Proteasome PF00227.26 ORY85311.1 - 2.9e-32 111.7 0.0 3.5e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit YtzH PF14165.6 ORY85311.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 YtzH-like protein EnY2 PF10163.9 ORY85312.1 - 4.1e-19 68.7 0.0 4.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF1708 PF08101.11 ORY85313.1 - 3.9e-26 92.2 0.0 7.1e-24 84.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.27 ORY85313.1 - 9.8e-07 28.7 0.0 2.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Aldo_ket_red PF00248.21 ORY85314.1 - 5.9e-41 140.6 0.0 7.5e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RIBIOP_C PF04950.12 ORY85315.1 - 1.4e-94 316.8 0.0 1.4e-94 316.8 0.0 2.3 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY85315.1 - 4e-23 81.3 0.0 1.3e-22 79.7 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 ORY85315.1 - 4e-07 29.8 0.0 8.6e-05 22.2 0.0 2.8 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORY85315.1 - 2.2e-05 24.9 0.0 8.5e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain Rtf2 PF04641.12 ORY85315.1 - 0.00035 20.0 8.2 0.00035 20.0 8.2 2.8 3 0 0 3 3 2 1 Rtf2 RING-finger AAA_22 PF13401.6 ORY85315.1 - 0.00065 20.0 0.2 0.0026 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY85315.1 - 0.00081 19.3 0.1 0.0085 16.0 0.0 2.2 1 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 ORY85315.1 - 0.0041 17.6 0.0 0.015 15.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 ORY85315.1 - 0.0068 16.5 0.2 0.024 14.7 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 ORY85315.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 ORY85315.1 - 0.023 15.2 3.1 0.039 14.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 ORY85315.1 - 0.037 13.2 1.2 0.044 13.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 ORY85315.1 - 0.044 14.2 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 ORY85315.1 - 0.047 13.5 3.7 0.12 12.1 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 ORY85315.1 - 0.048 13.8 0.1 0.21 11.8 0.1 2.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY85315.1 - 0.079 13.4 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Adeno_IVa2 PF02456.15 ORY85315.1 - 0.15 10.8 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF87 PF01935.17 ORY85315.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_17 PF13207.6 ORY85315.1 - 6.5 7.2 10.9 13 6.2 0.0 3.6 3 0 0 3 3 2 0 AAA domain DnaJ PF00226.31 ORY85316.1 - 2.5e-08 33.9 0.0 4.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain CRISPR_Cse2 PF09485.10 ORY85316.1 - 0.049 14.2 1.4 0.25 11.9 0.0 2.4 2 1 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) SR-25 PF10500.9 ORY85316.1 - 2.8 7.5 10.4 5.2 6.6 10.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SURF2 PF05477.11 ORY85317.1 - 6.1 6.5 10.1 11 5.6 3.0 2.2 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Peptidase_S10 PF00450.22 ORY85318.1 - 3.7e-202 672.3 0.0 3.2e-100 336.5 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Hydrolase_4 PF12146.8 ORY85318.1 - 0.016 14.5 0.0 19 4.4 0.0 3.9 4 0 0 4 4 4 0 Serine aminopeptidase, S33 DUF2920 PF11144.8 ORY85318.1 - 0.02 14.1 0.0 5 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Acetyltransf_3 PF13302.7 ORY85319.1 - 5.8e-21 75.6 0.0 1.1e-20 74.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY85319.1 - 0.001 18.8 0.6 0.14 11.9 0.3 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY85319.1 - 0.004 17.1 0.0 0.0075 16.2 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein UBA_3 PF09288.10 ORY85319.1 - 0.02 14.7 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain SH3_2 PF07653.17 ORY85319.1 - 0.087 12.5 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Variant SH3 domain DNA_pol_B PF00136.21 ORY85320.1 - 8e-151 502.8 0.6 1.1e-150 502.4 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY85320.1 - 4.1e-85 285.9 0.0 7e-85 285.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY85320.1 - 2.8e-18 66.1 5.4 6e-18 65.1 5.4 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 ORY85320.1 - 0.009 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 ORY85320.1 - 0.066 12.1 0.6 0.15 10.9 0.1 1.8 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 ORY85320.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 3'-5' exonuclease C1_1 PF00130.22 ORY85320.1 - 9.5 6.2 7.3 2.4e+02 1.7 7.3 2.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SKI PF01202.22 ORY85321.1 - 8.5e-07 29.2 0.0 5.7e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 ORY85321.1 - 0.0022 18.2 0.0 0.0032 17.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY85321.1 - 0.0034 17.9 0.1 0.018 15.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY85321.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 ORY85321.1 - 0.017 15.5 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 ORY85321.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase Cytidylate_kin2 PF13189.6 ORY85321.1 - 0.025 14.7 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_16 PF13191.6 ORY85321.1 - 0.1 12.9 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain OHCU_decarbox PF09349.10 ORY85322.1 - 1.7e-31 109.8 0.0 2.1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Methyltransf_16 PF10294.9 ORY85323.1 - 2.6e-14 53.3 0.0 6e-14 52.1 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase HAUS6_N PF14661.6 ORY85324.1 - 4.5e-10 39.5 0.3 6.9e-10 38.9 0.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus G-alpha PF00503.20 ORY85325.1 - 5.2e-65 219.9 0.0 7.6e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit HD_3 PF13023.6 ORY85325.1 - 1.1e-42 145.8 0.0 2.3e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 ORY85325.1 - 6.9e-12 45.5 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Arf PF00025.21 ORY85325.1 - 2.4e-06 27.1 0.0 0.00073 19.0 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family PH PF00169.29 ORY85325.1 - 0.00012 22.6 0.0 0.00026 21.5 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF815 PF05673.13 ORY85325.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORY85325.1 - 0.024 14.9 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain HD PF01966.22 ORY85325.1 - 0.043 14.0 0.1 0.091 13.0 0.1 1.6 1 0 0 1 1 1 0 HD domain FtsK_SpoIIIE PF01580.18 ORY85325.1 - 0.048 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 ORY85325.1 - 0.064 13.6 0.9 0.18 12.1 0.2 2.1 1 1 1 2 2 2 0 AAA ATPase domain NACHT PF05729.12 ORY85325.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 ORY85325.1 - 0.084 11.8 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 ORY85325.1 - 0.099 13.2 0.3 0.38 11.2 0.1 2.0 1 1 1 2 2 2 0 ABC transporter AAA_29 PF13555.6 ORY85325.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 ORY85325.1 - 0.14 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Septin IIGP PF05049.13 ORY85325.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.23 ORY85325.1 - 0.18 11.9 0.0 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 ORY85325.1 - 0.23 11.0 0.0 0.62 9.6 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4203 PF13886.6 ORY85326.1 - 5.7e-20 71.8 21.3 7.5e-20 71.5 21.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Sacchrp_dh_NADP PF03435.18 ORY85328.1 - 3.9e-20 72.4 0.4 7.6e-20 71.5 0.4 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 ORY85328.1 - 2.5e-05 24.0 0.5 3.9e-05 23.3 0.5 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY85328.1 - 0.00092 19.1 0.3 0.0017 18.3 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY85328.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF417 PF04224.12 ORY85328.1 - 0.13 11.8 0.7 0.38 10.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF417 Semialdhyde_dh PF01118.24 ORY85328.1 - 0.16 12.4 0.1 0.43 11.0 0.1 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 ORY85328.1 - 0.19 11.2 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Frag1 PF10277.9 ORY85328.1 - 0.67 9.4 10.9 1.9 8.0 11.0 1.7 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family Phe_tRNA-synt_N PF02912.18 ORY85329.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Ribosomal_L7Ae PF01248.26 ORY85330.1 - 4.6e-22 77.5 0.1 8.1e-22 76.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3557 PF12078.8 ORY85331.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) WD40 PF00400.32 ORY85332.1 - 6.9e-06 26.7 1.8 0.13 13.2 0.1 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY85332.1 - 0.00029 21.1 0.3 0.34 11.2 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 ORY85332.1 - 0.019 14.1 0.0 0.11 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Lactamase_B_2 PF12706.7 ORY85333.1 - 2.2e-36 125.2 0.1 5e-36 124.1 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY85333.1 - 3.5e-11 43.3 0.0 3.6e-10 40.0 0.0 2.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY85333.1 - 0.0098 15.9 1.3 0.041 13.9 1.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF4453 PF14627.6 ORY85334.1 - 0.00098 19.2 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4453) EMP24_GP25L PF01105.24 ORY85336.1 - 2.3e-47 161.3 0.3 2.7e-47 161.1 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD A2M PF00207.22 ORY85336.1 - 0.003 17.4 0.1 0.006 16.4 0.1 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin family SIR2_2 PF13289.6 ORY85336.1 - 0.083 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 SIR2-like domain HSA PF07529.13 ORY85337.1 - 2.3e-11 43.8 1.1 2.3e-11 43.8 1.1 2.9 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 ORY85337.1 - 1.8e-08 34.5 0.0 3.8e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY85337.1 - 6.9e-07 29.4 0.1 1.8e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain MccV PF17508.2 ORY85337.1 - 0.046 14.3 4.9 0.21 12.2 4.9 2.1 1 0 0 1 1 1 0 Microcin V bacteriocin BAR_2 PF10455.9 ORY85338.1 - 1.9e-39 135.6 0.0 4.2e-39 134.4 0.0 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORY85338.1 - 6.7e-15 55.4 0.3 1.5e-13 51.0 0.3 2.2 1 1 0 1 1 1 1 BAR domain L27_2 PF09045.10 ORY85338.1 - 0.11 12.5 0.4 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 L27_2 Proteasome PF00227.26 ORY85339.1 - 6.3e-45 153.0 0.2 8.4e-45 152.6 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 ORY85339.1 - 4.5e-10 38.8 1.7 4.5e-10 38.8 1.7 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal RRM_1 PF00076.22 ORY85340.1 - 8.1e-31 105.7 0.2 5.8e-09 35.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY85340.1 - 7.1e-09 35.4 0.0 0.04 13.8 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif DUF1866 PF08952.11 ORY85340.1 - 0.0042 16.9 0.0 2.7 7.8 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1866) RRM_7 PF16367.5 ORY85340.1 - 0.029 14.5 0.0 78 3.5 0.0 3.6 3 0 0 3 3 3 0 RNA recognition motif RRM_3 PF08777.11 ORY85340.1 - 0.078 13.0 0.2 7.8 6.6 0.1 2.6 2 0 0 2 2 2 0 RNA binding motif tRNA-synt_2 PF00152.20 ORY85341.1 - 3e-84 282.8 0.0 4.3e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY85341.1 - 3.9e-12 46.0 0.0 7.2e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SurE PF01975.17 ORY85342.1 - 2.8e-48 164.3 0.0 3.6e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_2 PF13477.6 ORY85342.1 - 0.039 14.0 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 ORY85342.1 - 0.18 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 2-Hacid_dh_C PF02826.19 ORY85344.1 - 1e-50 171.6 0.0 1.5e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY85344.1 - 1.7e-07 30.9 0.0 1.9e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY85344.1 - 0.00075 19.7 0.4 0.0032 17.7 0.0 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORY85344.1 - 0.09 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Peptidase_S8 PF00082.22 ORY85346.1 - 1.6e-33 116.3 9.3 3.6e-33 115.1 9.3 1.5 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY85346.1 - 8.4e-10 39.2 0.2 2e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 SBDS PF01172.18 ORY85349.1 - 2.1e-16 59.7 0.0 2.8e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Swi6_N PF18530.1 ORY85349.1 - 0.0047 17.0 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 Swi6 N-terminal domain Pyr_redox_2 PF07992.14 ORY85350.1 - 1.2e-31 110.0 0.1 9.5e-29 100.5 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY85350.1 - 1.8e-12 47.6 0.0 2.1e-08 34.6 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY85350.1 - 6.1e-06 25.7 0.0 4.6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY85350.1 - 0.00028 20.1 1.0 0.68 8.9 0.0 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.6 ORY85350.1 - 0.00036 19.8 0.0 0.0053 16.0 0.1 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 ORY85350.1 - 0.00067 18.6 0.2 3 6.6 0.2 3.2 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_9 PF13454.6 ORY85350.1 - 0.00075 19.5 0.9 4.2 7.4 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 ORY85350.1 - 0.0016 17.7 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORY85350.1 - 0.0033 16.2 0.5 0.88 8.2 0.1 3.2 2 1 1 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.6 ORY85350.1 - 0.0045 17.2 1.5 3 8.2 0.2 3.0 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.17 ORY85350.1 - 0.0083 16.7 0.3 0.06 13.9 0.0 2.5 3 1 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 ORY85350.1 - 0.016 14.3 0.0 1.2 8.1 0.0 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ORY85350.1 - 0.025 13.9 0.1 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 ORY85351.1 - 2.2e-39 135.4 0.3 2.6e-39 135.2 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY85351.1 - 4.3e-15 56.0 2.6 3.3e-13 50.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY85351.1 - 6.9e-09 35.4 0.1 6.9e-09 35.4 0.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY85351.1 - 2.4e-05 23.6 0.5 0.0037 16.4 0.1 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein K_oxygenase PF13434.6 ORY85351.1 - 4.5e-05 22.8 0.7 5.9e-05 22.4 0.1 1.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY85351.1 - 0.00023 20.9 5.7 0.18 11.3 0.3 3.3 2 2 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY85351.1 - 0.00075 19.7 2.2 0.051 13.8 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY85351.1 - 0.0013 17.7 2.5 0.42 9.4 0.5 2.8 2 1 1 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.24 ORY85351.1 - 0.002 17.2 4.4 0.24 10.4 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 ORY85351.1 - 0.0049 16.1 0.3 0.65 9.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORY85351.1 - 0.0058 15.4 6.9 0.079 11.6 0.4 3.3 3 1 1 4 4 4 1 HI0933-like protein NAD_binding_9 PF13454.6 ORY85351.1 - 0.0076 16.2 1.3 1.3 9.0 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 ORY85351.1 - 0.016 14.3 6.1 0.12 11.4 0.2 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A Peptidase_S13 PF02113.15 ORY85351.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family YAcAr PF10686.9 ORY85351.1 - 0.043 13.8 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family NAD_binding_7 PF13241.6 ORY85351.1 - 0.047 14.1 0.1 2.9 8.4 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF4147 PF13660.6 ORY85351.1 - 0.051 13.1 0.7 5.2 6.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) TrkA_N PF02254.18 ORY85351.1 - 0.31 11.3 1.0 11 6.4 0.1 2.9 2 1 0 2 2 2 0 TrkA-N domain FAD_oxidored PF12831.7 ORY85351.1 - 0.78 9.0 5.8 0.13 11.5 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GAF_3 PF13492.6 ORY85352.1 - 1.1e-06 29.0 0.0 0.033 14.5 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 ORY85352.1 - 0.0063 17.1 0.0 0.062 13.9 0.0 2.4 3 0 0 3 3 3 1 GAF domain GAF_2 PF13185.6 ORY85352.1 - 0.045 14.0 0.0 5.7 7.2 0.0 2.8 2 1 0 2 2 2 0 GAF domain HJURP_mid PF12346.8 ORY85352.1 - 0.62 10.5 3.3 9 6.8 0.0 2.7 3 0 0 3 3 3 0 Holliday junction recognition protein-associated repeat Lectin_leg-like PF03388.13 ORY85353.1 - 7.8e-65 218.4 0.1 9.3e-65 218.2 0.1 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 ORY85353.1 - 3.7e-09 36.9 0.9 4.9e-09 36.5 0.9 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 ORY85353.1 - 3.2e-05 23.6 0.0 0.0057 16.2 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain DUF2142 PF09913.9 ORY85353.1 - 0.025 13.4 0.1 0.04 12.8 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) WD40 PF00400.32 ORY85354.1 - 0.021 15.7 15.1 2 9.4 0.7 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat Mito_carr PF00153.27 ORY85355.1 - 1.6e-26 92.1 6.3 2.6e-13 49.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_zinc_N PF00107.26 ORY85356.1 - 5.8e-18 65.1 0.0 8.9e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY85356.1 - 3.5e-14 52.6 0.0 7.9e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY85356.1 - 1.5e-10 42.2 0.0 2.6e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 ORY85356.1 - 2.2e-05 24.4 0.0 0.00097 19.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2855) DUF4205 PF13898.6 ORY85356.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) Rer1 PF03248.13 ORY85357.1 - 1e-74 249.9 0.1 1.2e-74 249.7 0.1 1.0 1 0 0 1 1 1 1 Rer1 family FA_desaturase PF00487.24 ORY85357.1 - 0.0047 16.8 4.7 0.35 10.7 0.7 2.0 2 0 0 2 2 2 2 Fatty acid desaturase DUF2208 PF09973.9 ORY85357.1 - 0.012 15.3 1.3 0.012 15.3 1.3 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Sel1 PF08238.12 ORY85358.1 - 5.4e-16 58.7 39.3 8.3e-05 23.1 1.6 10.5 10 0 0 10 10 10 5 Sel1 repeat TPR_7 PF13176.6 ORY85358.1 - 4.7e-06 26.3 0.4 1.7 8.8 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY85358.1 - 6.3e-05 22.6 3.7 0.041 13.7 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY85358.1 - 7.4e-05 22.7 3.6 0.071 13.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY85358.1 - 0.0046 17.0 15.6 0.0074 16.3 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY85358.1 - 0.0053 17.0 11.2 0.016 15.5 1.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY85358.1 - 0.021 14.7 0.6 0.57 10.1 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY85358.1 - 0.029 15.0 0.2 0.029 15.0 0.2 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY85358.1 - 0.034 14.9 2.3 33 5.7 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY85358.1 - 0.084 13.5 13.4 20 6.1 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat ABA_GPCR PF12430.8 ORY85359.1 - 7e-40 136.7 7.1 7e-40 136.7 7.1 2.3 2 1 1 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 ORY85359.1 - 2.2e-16 59.7 0.1 2.2e-16 59.7 0.1 2.3 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal Acetyltransf_7 PF13508.7 ORY85360.1 - 6.1e-05 23.4 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY85360.1 - 8.7e-05 22.7 0.0 0.00015 22.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY85360.1 - 0.038 13.9 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TRP PF06011.12 ORY85361.1 - 1.1e-30 106.7 1.3 4.3e-30 104.8 1.3 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Pep1_7 PF17232.2 ORY85361.1 - 0.19 12.2 0.1 0.67 10.5 0.1 2.0 1 0 0 1 1 1 0 Elicitor peptide 1-7 Dioxygenase_C PF00775.21 ORY85362.1 - 0.014 14.9 0.0 0.09 12.2 0.0 2.0 2 0 0 2 2 2 0 Dioxygenase SprA-related PF12118.8 ORY85362.1 - 4 6.5 23.4 0.042 13.0 10.0 2.3 2 0 0 2 2 2 0 SprA-related family Foie-gras_1 PF11817.8 ORY85363.1 - 6.2e-39 134.1 0.0 6.4e-37 127.5 0.0 2.4 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 ORY85363.1 - 4.8e-19 68.6 0.0 9e-13 47.8 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 ORY85363.1 - 0.0015 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TPR_12 PF13424.6 ORY85363.1 - 0.011 16.0 2.2 0.17 12.2 0.5 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Transglut_C PF00927.22 ORY85363.1 - 0.059 13.5 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain Fis1_TPR_C PF14853.6 ORY85363.1 - 0.096 12.8 0.1 0.78 9.9 0.0 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat MafB19-deam PF14437.6 ORY85363.1 - 0.22 11.3 0.2 0.38 10.5 0.2 1.3 1 0 0 1 1 1 0 MafB19-like deaminase TPR_2 PF07719.17 ORY85363.1 - 0.49 10.6 1.6 20 5.6 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat A_deaminase PF00962.22 ORY85364.1 - 4.9e-79 266.0 0.0 5.7e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Stevor PF17410.2 ORY85365.1 - 0.076 12.5 2.0 0.092 12.3 0.1 1.8 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame adh_short PF00106.25 ORY85366.1 - 1.2e-35 122.8 0.0 1.6e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY85366.1 - 8.2e-18 64.8 0.0 1.1e-17 64.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY85366.1 - 2.4e-05 24.3 0.1 4.2e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 KR domain SAM_MT PF04445.13 ORY85366.1 - 0.011 15.2 0.1 0.016 14.6 0.1 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase PI3_PI4_kinase PF00454.27 ORY85369.1 - 1.3e-50 172.6 0.0 2e-50 171.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ORY85369.1 - 1.5e-30 106.7 0.0 2.7e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 ORY85369.1 - 6.1e-23 80.7 0.0 1.9e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 ORY85369.1 - 4.2e-09 36.1 0.0 9.4e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 ORY85369.1 - 0.015 15.2 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_11 PF13414.6 ORY85369.1 - 0.037 13.7 0.3 0.12 12.1 0.3 1.8 1 0 0 1 1 1 0 TPR repeat GATA PF00320.27 ORY85370.1 - 2.3e-06 27.1 5.9 4e-06 26.3 5.9 1.4 1 0 0 1 1 1 1 GATA zinc finger ELO PF01151.18 ORY85372.1 - 7.8e-59 199.2 25.6 9.8e-59 198.9 25.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Zn_clus PF00172.18 ORY85373.1 - 2.8e-05 24.2 13.8 4.5e-05 23.5 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEAT_EZ PF13513.6 ORY85374.1 - 3e-26 91.5 21.7 2.9e-12 46.8 0.0 11.0 11 2 2 13 13 12 6 HEAT-like repeat HEAT PF02985.22 ORY85374.1 - 1.2e-16 59.3 8.1 0.01 16.0 0.0 9.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 ORY85374.1 - 2.7e-11 43.7 0.0 0.2 12.0 0.0 6.8 5 3 1 6 6 6 2 HEAT repeats IBN_N PF03810.19 ORY85374.1 - 1.3e-09 37.8 0.0 7.5e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 ORY85374.1 - 4.7e-06 26.7 0.0 0.83 9.7 0.0 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 ORY85374.1 - 8.5e-06 25.6 1.6 11 6.2 0.0 7.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 ORY85374.1 - 7.3e-05 22.6 0.0 2.3 8.2 0.0 4.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3437) Vac14_Fab1_bd PF12755.7 ORY85374.1 - 0.00092 19.8 0.0 6.9 7.3 0.0 4.4 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 ORY85374.1 - 0.0047 17.1 0.0 0.081 13.1 0.0 3.0 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 ORY85374.1 - 0.033 12.8 0.1 4.4 5.8 0.0 2.9 3 0 0 3 3 3 0 Adaptin N terminal region UNC45-central PF11701.8 ORY85374.1 - 0.035 14.1 0.4 0.2 11.6 0.1 2.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Xpo1 PF08389.12 ORY85374.1 - 0.049 13.7 0.0 0.28 11.2 0.0 2.4 1 0 0 1 1 1 0 Exportin 1-like protein MMS19_C PF12460.8 ORY85374.1 - 0.063 12.4 6.1 5.7 5.9 0.1 4.8 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal TIP120 PF08623.10 ORY85374.1 - 0.12 12.2 0.0 1.1 9.0 0.0 2.6 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Tti2 PF10521.9 ORY85374.1 - 0.16 11.5 0.1 14 5.1 0.0 3.7 2 2 2 4 4 4 0 Tti2 family DUF4611 PF15387.6 ORY85374.1 - 0.37 11.0 3.0 37 4.6 1.6 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4611) eRF1_1 PF03463.15 ORY85375.1 - 1.2e-47 161.1 0.2 1.8e-47 160.6 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 ORY85375.1 - 2.7e-24 85.8 0.0 5.8e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 ORY85375.1 - 2e-22 80.0 0.0 3.2e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 ORC2 PF04084.14 ORY85376.1 - 8.1e-63 212.3 0.0 1e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 TrbC_Ftype PF09673.10 ORY85376.1 - 0.036 14.1 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Ribosomal_60s PF00428.19 ORY85376.1 - 4.5 7.9 8.6 15 6.3 0.1 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein RNA_pol_Rpb8 PF03870.15 ORY85377.1 - 1.1e-46 158.5 0.0 1.2e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF5082 PF16888.5 ORY85378.1 - 0.018 15.3 0.8 0.029 14.6 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) FlxA PF14282.6 ORY85378.1 - 0.02 14.9 1.8 0.02 14.9 1.8 1.8 2 0 0 2 2 2 0 FlxA-like protein PUL PF08324.11 ORY85378.1 - 0.025 13.8 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 PUL domain DUF5321 PF17254.2 ORY85378.1 - 1.4 8.3 6.4 23 4.4 6.3 2.5 1 1 0 1 1 1 0 Family of unknown function (DUF5321) Glyco_transf_28 PF03033.20 ORY85379.1 - 2.4e-25 89.2 0.0 5.4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ORY85379.1 - 9.3e-05 21.4 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 ORY85379.1 - 0.0013 19.0 0.0 0.0047 17.2 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain DUF3323 PF11796.8 ORY85379.1 - 0.002 18.0 0.3 0.002 18.0 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminus (DUF3323) VPS13_C PF16909.5 ORY85379.1 - 0.026 14.3 0.7 0.5 10.1 0.2 2.8 2 1 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal F-box-like PF12937.7 ORY85380.1 - 0.0009 19.1 0.0 0.0023 17.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like FNIP PF05725.12 ORY85380.1 - 0.2 11.9 2.5 4.7 7.5 0.3 2.7 2 0 0 2 2 2 0 FNIP Repeat F-box-like PF12937.7 ORY85381.1 - 4.7e-06 26.4 1.9 1.5e-05 24.8 0.1 2.5 2 1 0 2 2 2 1 F-box-like Nitro_FeMo-Co PF02579.17 ORY85381.1 - 0.089 13.1 1.0 8.1 6.9 0.0 2.8 3 0 0 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DUF4588 PF15251.6 ORY85383.1 - 0.0021 17.9 0.0 0.0025 17.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Ank_5 PF13857.6 ORY85384.1 - 4.1e-28 97.1 0.7 1.1e-08 35.2 0.0 4.6 2 1 3 5 5 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY85384.1 - 2.5e-26 91.7 0.8 1.6e-10 41.3 0.1 4.5 3 1 2 5 5 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY85384.1 - 8.1e-25 87.2 0.0 7.6e-12 45.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY85384.1 - 1.9e-20 70.8 0.0 0.0017 18.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat FYVE PF01363.21 ORY85384.1 - 1.3e-17 63.7 9.6 1.3e-17 63.7 9.6 2.6 3 0 0 3 3 3 1 FYVE zinc finger Ank PF00023.30 ORY85384.1 - 2e-16 59.6 2.6 0.0013 19.1 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat zf-RING_2 PF13639.6 ORY85384.1 - 5.3e-08 33.1 4.2 5.3e-08 33.1 4.2 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY85384.1 - 0.00019 21.2 3.4 0.00019 21.2 3.4 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY85384.1 - 0.00029 20.5 4.8 0.00073 19.2 4.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY85384.1 - 0.0049 16.9 4.9 0.0049 16.9 4.9 2.6 3 0 0 3 3 2 1 RING-type zinc-finger FYVE_2 PF02318.16 ORY85384.1 - 0.0064 16.7 3.2 0.0064 16.7 3.2 1.9 2 0 0 2 2 1 1 FYVE-type zinc finger zf-C3HC4 PF00097.25 ORY85384.1 - 0.0065 16.3 2.6 0.0065 16.3 2.6 2.9 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 ORY85384.1 - 0.017 15.3 3.1 0.017 15.3 3.1 2.7 3 0 0 3 3 1 0 RING-variant domain Pex24p PF06398.11 ORY85384.1 - 0.17 10.8 1.3 0.25 10.3 1.3 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin zf-rbx1 PF12678.7 ORY85384.1 - 0.58 10.5 10.1 0.04 14.2 3.9 2.4 2 1 0 2 2 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 ORY85384.1 - 1.2 9.4 6.1 0.49 10.6 2.8 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain Cys_Met_Meta_PP PF01053.20 ORY85385.1 - 6.3e-59 199.4 0.0 1.8e-58 197.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY85385.1 - 0.055 12.4 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Velvet PF11754.8 ORY85386.1 - 6.4e-67 226.1 3.9 1.2e-66 225.2 3.9 1.4 1 1 0 1 1 1 1 Velvet factor ADH_zinc_N PF00107.26 ORY85387.1 - 3e-19 69.3 0.0 4.3e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY85387.1 - 4.5e-16 58.7 0.0 9.7e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 ORY85387.1 - 1.4e-06 29.4 0.0 2.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PPR_2 PF13041.6 ORY85388.1 - 1.7e-32 111.3 0.0 2.8e-10 40.2 0.0 8.2 7 1 2 9 9 9 6 PPR repeat family PPR PF01535.20 ORY85388.1 - 6.7e-25 85.6 0.1 0.00012 22.1 0.1 10.0 11 0 0 11 11 11 5 PPR repeat PPR_1 PF12854.7 ORY85388.1 - 6.3e-23 80.2 0.1 0.00054 19.6 0.0 7.8 8 0 0 8 8 8 5 PPR repeat PPR_3 PF13812.6 ORY85388.1 - 6.1e-21 74.3 0.0 1.6e-06 28.1 0.0 6.0 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY85388.1 - 7.3e-11 41.8 0.1 4.6e-08 32.7 0.0 3.4 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP Spectrin PF00435.21 ORY85388.1 - 0.027 15.0 0.2 0.11 13.0 0.2 2.0 1 0 0 1 1 1 0 Spectrin repeat PriCT_1 PF08708.11 ORY85388.1 - 0.094 12.5 0.0 0.37 10.5 0.0 2.0 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Tim17 PF02466.19 ORY85389.1 - 0.45 10.9 5.8 0.83 10.1 5.8 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family RdRP PF05183.12 ORY85390.1 - 3.5e-153 511.4 0.0 4.9e-153 510.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RasGEF PF00617.19 ORY85391.1 - 1.4e-42 145.9 0.2 2.5e-42 145.0 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY85391.1 - 1.4e-09 38.1 0.6 6.1e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif TAF4 PF05236.14 ORY85391.1 - 0.0095 15.7 2.0 0.014 15.1 1.3 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family BEX PF04538.12 ORY85391.1 - 0.029 15.0 3.2 0.072 13.7 3.2 1.6 1 0 0 1 1 1 0 Brain expressed X-linked like family AAA_33 PF13671.6 ORY85391.1 - 0.047 13.9 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY85391.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ANAPC4 PF12896.7 ORY85393.1 - 4.8e-24 85.0 0.0 7.4e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 ORY85393.1 - 0.0021 18.3 0.0 0.04 14.2 0.0 2.8 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L32p PF01783.23 ORY85394.1 - 1.9e-13 50.4 8.4 2.5e-13 50.1 8.4 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 ORY85394.1 - 0.0024 17.7 3.9 0.006 16.5 3.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 Indigoidine_A PF04227.12 ORY85395.1 - 1.2e-113 379.3 0.9 1.7e-113 378.8 0.4 1.5 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 ORY85395.1 - 1.3e-19 70.7 0.3 3.1e-11 43.1 0.0 3.0 2 2 0 2 2 2 2 pfkB family carbohydrate kinase PrmA PF06325.13 ORY85396.1 - 6.7e-14 52.0 0.2 9.9e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY85396.1 - 6.4e-11 42.1 0.6 9e-07 28.6 0.2 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Cons_hypoth95 PF03602.15 ORY85396.1 - 1.2e-08 34.8 0.4 1.5e-06 28.0 0.1 2.4 1 1 2 3 3 3 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 ORY85396.1 - 1.6e-07 31.2 0.0 2.7e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY85396.1 - 2.1e-06 28.4 0.0 6e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY85396.1 - 0.00044 20.3 0.0 0.0007 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY85396.1 - 0.0009 19.2 0.1 0.0016 18.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 ORY85396.1 - 0.0014 18.2 0.0 0.0026 17.4 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 ORY85396.1 - 0.0017 18.1 0.2 0.0066 16.2 0.2 1.9 1 1 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 ORY85396.1 - 0.0021 17.8 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltrans_SAM PF10672.9 ORY85396.1 - 0.0032 16.7 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase UPF0020 PF01170.18 ORY85396.1 - 0.0047 16.6 0.1 1.3 8.7 0.0 2.2 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 ORY85396.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORY85396.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase FmrO PF07091.11 ORY85396.1 - 0.029 13.9 0.2 0.04 13.5 0.2 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.12 ORY85396.1 - 0.042 14.5 0.1 0.12 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORY85396.1 - 0.11 13.3 0.0 0.56 11.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain CPSase_L_D3 PF02787.19 ORY85396.1 - 0.12 12.7 0.3 0.62 10.4 0.0 2.0 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PNGaseA PF12222.8 ORY85397.1 - 1.2e-102 344.1 0.0 1.6e-102 343.6 0.0 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A AD PF09793.9 ORY85398.1 - 1.1e-23 83.2 0.0 1.6e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain PGC7_Stella PF15549.6 ORY85398.1 - 0.27 11.2 1.4 0.43 10.5 1.4 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain GTP_EFTU PF00009.27 ORY85400.1 - 2.2e-57 193.7 0.1 3.4e-57 193.1 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY85400.1 - 5.7e-39 132.6 0.6 1.6e-37 128.0 0.1 2.7 3 0 0 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 ORY85400.1 - 8.9e-31 105.8 0.0 1.9e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY85400.1 - 1.4e-22 79.5 0.1 4e-22 78.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY85400.1 - 1.5e-14 54.1 0.9 3.6e-14 52.9 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY85400.1 - 1.5e-05 24.9 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain RCC1 PF00415.18 ORY85401.1 - 1.5e-34 118.4 4.0 1.5e-09 38.4 0.1 7.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY85401.1 - 2.9e-12 46.0 26.9 6.1e-06 25.9 0.1 6.4 8 0 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.29 ORY85401.1 - 5.6e-11 42.2 9.0 1.1e-10 41.2 9.0 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 ORY85401.1 - 0.074 13.0 2.5 0.21 11.5 2.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 ORY85401.1 - 0.083 13.0 2.7 0.23 11.6 2.7 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-HC5HC2H PF13771.6 ORY85401.1 - 0.11 12.7 1.9 0.22 11.8 1.9 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_2 PF03107.16 ORY85401.1 - 0.14 12.5 3.4 0.33 11.3 3.4 1.6 1 0 0 1 1 1 0 C1 domain SUKH-3 PF14433.6 ORY85401.1 - 0.2 12.1 0.5 10 6.6 0.1 2.6 2 0 0 2 2 2 0 SUKH-3 immunity protein PHD_2 PF13831.6 ORY85401.1 - 0.51 9.9 2.8 1.2 8.8 2.8 1.7 1 0 0 1 1 1 0 PHD-finger PHD_4 PF16866.5 ORY85401.1 - 5.2 7.2 11.2 16 5.7 11.2 1.9 1 1 0 1 1 1 0 PHD-finger Acetyltransf_1 PF00583.25 ORY85403.1 - 0.00098 19.3 0.0 0.0049 17.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF3410 PF11890.8 ORY85405.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) Ribosomal_S8 PF00410.19 ORY85406.1 - 3.2e-15 56.2 0.0 1.5e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 DUF3040 PF11239.8 ORY85407.1 - 0.26 11.6 7.2 0.24 11.7 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) TctB PF07331.11 ORY85407.1 - 0.37 11.0 6.8 0.56 10.5 6.8 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family FA_hydroxylase PF04116.13 ORY85408.1 - 0.03 14.7 1.9 0.03 14.7 1.9 2.4 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily PufQ PF05398.11 ORY85408.1 - 0.14 12.3 0.4 0.31 11.2 0.4 1.6 1 0 0 1 1 1 0 PufQ cytochrome subunit DUF3402 PF11882.8 ORY85409.1 - 3.2e-135 451.8 0.6 4.1e-134 448.2 0.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 ORY85409.1 - 2.1e-74 250.3 0.0 3.4e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein CENP-W PF15510.6 ORY85409.1 - 0.44 10.8 2.1 1 9.7 0.1 2.3 2 0 0 2 2 2 0 CENP-W protein Cwf_Cwc_15 PF04889.12 ORY85409.1 - 3.8 7.2 12.2 0.7 9.6 7.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NPC1_N PF16414.5 ORY85410.1 - 3.2e-74 249.6 5.7 3.2e-74 249.6 5.7 1.5 2 0 0 2 2 2 1 Niemann-Pick C1 N terminus Patched PF02460.18 ORY85410.1 - 2.6e-68 230.9 4.4 1.1e-34 119.6 0.4 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 ORY85410.1 - 4.4e-44 150.0 4.5 4.4e-44 150.0 4.5 4.1 3 2 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 ORY85410.1 - 0.00055 19.8 1.1 0.0011 18.9 1.1 1.4 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 ORY85410.1 - 0.00068 17.4 6.7 0.0011 16.8 6.7 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 ORY85410.1 - 0.012 14.5 0.2 0.012 14.5 0.2 4.1 4 0 0 4 4 4 0 MMPL family Uroplakin_II PF07353.12 ORY85410.1 - 0.032 13.7 0.3 0.096 12.2 0.3 1.8 1 0 0 1 1 1 0 Uroplakin II JmjC PF02373.22 ORY85411.1 - 9.9e-10 38.9 0.0 1.9e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARF7EP_C PF14949.6 ORY85411.1 - 1.8 9.2 9.1 2 9.1 2.3 2.6 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Stealth_CR3 PF17102.5 ORY85412.1 - 2.3e-12 46.6 0.1 5.3e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Stealth_CR2 PF11380.8 ORY85412.1 - 1.5e-10 41.2 0.0 8.6e-07 29.1 0.0 2.8 3 0 0 3 3 3 2 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 ORY85412.1 - 9.1e-09 35.1 0.0 4.9e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR1 PF17101.5 ORY85412.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 TrmB PF01978.19 ORY85413.1 - 0.088 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ORY85413.1 - 0.098 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain Nup160 PF11715.8 ORY85414.1 - 8.5e-42 143.5 0.0 1.4e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 GPHR_N PF12537.8 ORY85414.1 - 0.088 12.9 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal TPR_16 PF13432.6 ORY85414.1 - 4.5 8.0 7.7 9.2 7.0 5.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY85414.1 - 5.7 7.4 7.9 3.8 8.0 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY85414.1 - 7.7 6.5 9.1 0.47 10.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Oxidored_molyb PF00174.19 ORY85415.1 - 1.1e-44 152.1 0.0 1.6e-43 148.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY85415.1 - 5.5e-13 49.1 0.0 5.1e-12 46.0 0.0 2.4 2 1 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain adh_short_C2 PF13561.6 ORY85416.1 - 6.5e-55 186.2 2.9 8.5e-55 185.9 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY85416.1 - 6.1e-53 179.2 2.2 7.6e-53 178.9 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY85416.1 - 8.2e-11 42.1 1.2 1.1e-10 41.7 1.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY85416.1 - 0.03 13.8 0.4 0.049 13.1 0.4 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ORY85416.1 - 0.11 12.3 1.0 0.31 10.9 0.5 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1749 PF08538.10 ORY85416.1 - 0.14 11.2 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) adh_short_C2 PF13561.6 ORY85417.1 - 6.1e-52 176.5 1.3 9.9e-52 175.8 1.3 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY85417.1 - 5.1e-50 169.7 0.8 6.5e-50 169.3 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY85417.1 - 9e-09 35.5 0.5 1.3e-08 35.0 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY85417.1 - 0.16 11.4 0.6 0.26 10.7 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ribosomal_L5_C PF00673.21 ORY85418.1 - 3.7e-21 75.1 0.0 6.3e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY85418.1 - 1.6e-20 73.2 0.1 3.3e-20 72.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 Rxt3 PF08642.10 ORY85419.1 - 9.3e-18 65.2 0.0 9.3e-18 65.2 0.0 3.5 2 2 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 ORY85419.1 - 0.086 13.0 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 LCCL domain Macoilin PF09726.9 ORY85419.1 - 1.3 7.5 6.7 2.2 6.8 6.7 1.3 1 0 0 1 1 1 0 Macoilin family POPLD PF08170.12 ORY85419.1 - 3.4 8.1 5.2 2.7 8.4 2.0 2.2 1 1 1 2 2 2 0 POPLD (NUC188) domain Presenilin PF01080.17 ORY85419.1 - 5 5.8 12.0 9.3 4.9 12.0 1.3 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 ORY85419.1 - 5 5.4 9.0 7.5 4.9 9.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor adh_short PF00106.25 ORY85420.1 - 4.4e-27 94.8 0.0 1.5e-25 89.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY85420.1 - 5.6e-13 49.0 0.0 9.9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY85420.1 - 1.9e-07 31.2 0.0 2.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY85420.1 - 0.00028 20.4 0.2 0.00048 19.7 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY85420.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase YEATS PF03366.16 ORY85421.1 - 6.5e-38 128.6 0.3 1e-37 127.9 0.3 1.3 1 0 0 1 1 1 1 YEATS family Nup54_57_C PF18570.1 ORY85421.1 - 0.029 14.0 3.1 0.033 13.8 2.0 1.6 1 1 0 1 1 1 0 NUP57/Nup54 C-terminal domain Sec3_C PF09763.9 ORY85421.1 - 0.12 10.8 0.4 0.15 10.4 0.4 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 CCDC-167 PF15188.6 ORY85421.1 - 0.44 10.9 2.7 0.73 10.2 2.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ribosomal_S10 PF00338.22 ORY85422.1 - 9.3e-23 80.3 0.0 1.4e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ATP_bind_1 PF03029.17 ORY85423.1 - 1.8e-76 257.2 0.0 2.2e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ORY85423.1 - 8.1e-06 25.5 0.0 0.00021 20.9 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.22 ORY85423.1 - 0.0009 18.9 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 ORY85423.1 - 0.001 19.1 0.0 0.0035 17.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 ORY85423.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 ORY85423.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 ORY85423.1 - 0.0026 17.4 0.0 0.041 13.5 0.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ORY85423.1 - 0.0034 17.9 0.0 0.0096 16.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 ORY85423.1 - 0.0043 17.2 0.1 0.014 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY85423.1 - 0.0046 17.3 0.1 0.018 15.4 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY85423.1 - 0.005 17.1 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY85423.1 - 0.01 14.9 0.0 0.44 9.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 ORY85423.1 - 0.011 15.5 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 ORY85423.1 - 0.021 14.6 0.3 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 ORY85423.1 - 0.028 14.0 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 ORY85423.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain G-alpha PF00503.20 ORY85423.1 - 0.034 13.3 0.1 0.9 8.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Arf PF00025.21 ORY85423.1 - 0.094 12.2 0.0 2.1 7.8 0.0 2.8 3 1 1 4 4 4 0 ADP-ribosylation factor family Styelin PF17562.2 ORY85423.1 - 0.12 12.7 0.3 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 Styelin Roc PF08477.13 ORY85423.1 - 0.14 12.4 0.0 1.5 9.1 0.0 2.3 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase PRK PF00485.18 ORY85423.1 - 0.14 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Ras PF00071.22 ORY85423.1 - 0.15 11.6 0.0 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 ORY85423.1 - 0.17 11.3 0.0 0.96 8.9 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit CLP1_P PF16575.5 ORY85423.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.6 2 0 0 2 2 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Viral_helicase1 PF01443.18 ORY85423.1 - 0.19 11.5 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 ORY85423.1 - 0.2 11.5 0.0 16 5.3 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase MFS_1 PF07690.16 ORY85930.1 - 2e-07 30.3 17.4 2e-07 30.3 17.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY85930.1 - 0.0053 16.5 0.2 0.0053 16.5 0.2 2.4 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 ASC PF00858.24 ORY85930.1 - 0.046 12.7 1.0 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel eIF-5a PF01287.20 ORY85931.1 - 2e-26 91.9 0.8 2.8e-26 91.4 0.8 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ORY85931.1 - 0.00044 20.2 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TgMIC1 PF11476.8 ORY85931.1 - 0.045 13.5 0.1 0.2 11.4 0.1 2.0 1 1 1 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 IL2RB_N1 PF18707.1 ORY85934.1 - 0.068 13.7 0.1 0.079 13.5 0.1 1.1 1 0 0 1 1 1 0 Interleukin-2 receptor subunit beta N-terminal domain 1 Pih1_fungal_CS PF18482.1 ORY85935.1 - 0.18 12.4 0.0 0.23 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal Pih1 CS domain BP28CT PF08146.12 ORY85937.1 - 1e-41 142.4 0.2 8e-41 139.5 0.5 2.5 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 ORY85937.1 - 2.8e-14 53.5 0.0 2.8e-14 53.5 0.0 5.1 6 1 0 7 7 7 1 U3 small nucleolar RNA-associated protein 10 Peptidase_M43 PF05572.13 ORY85938.1 - 6.7e-06 26.1 0.0 0.00037 20.4 0.0 2.4 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 ORY85938.1 - 0.0036 17.5 0.1 0.0094 16.1 0.1 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12 DUF4953 PF16313.5 ORY85938.1 - 0.0069 15.6 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Met-zincin Reprolysin_4 PF13583.6 ORY85938.1 - 0.0075 15.9 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ORY85938.1 - 0.011 15.6 0.1 0.017 15.0 0.1 1.5 1 1 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 ORY85938.1 - 0.023 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Mid1 PF12929.7 ORY85939.1 - 9.4e-76 255.7 0.1 1.2e-75 255.4 0.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 ORY85939.1 - 0.36 11.5 5.9 0.8 10.4 1.1 2.4 2 0 0 2 2 2 0 Fz domain Tfb4 PF03850.14 ORY85940.1 - 2.6e-90 302.7 0.1 3e-90 302.5 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 TetR_C_30 PF17939.1 ORY85940.1 - 0.074 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain PH_10 PF15411.6 ORY85941.1 - 3.8e-38 130.5 0.8 7.9e-38 129.5 0.8 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 ORY85941.1 - 1.2e-34 120.1 0.1 2.1e-34 119.4 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 ORY85941.1 - 1.4e-22 79.7 0.0 2.6e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 ORY85941.1 - 1.3e-13 50.7 0.0 2.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 PB1 domain DUF677 PF05055.12 ORY85941.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PH PF00169.29 ORY85941.1 - 0.1 13.1 0.1 0.2 12.2 0.1 1.4 1 0 0 1 1 1 0 PH domain DUF3419 PF11899.8 ORY85942.1 - 2.2e-141 471.5 0.0 2.9e-141 471.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 ORY85942.1 - 5.2e-12 45.9 0.0 2.9e-11 43.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY85942.1 - 1.6e-07 32.0 0.0 6e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY85942.1 - 7.8e-07 29.8 0.0 8.8e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY85942.1 - 1.8e-06 28.5 0.0 7.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY85942.1 - 8.7e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY85942.1 - 0.00037 20.3 0.0 0.00091 19.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Cyclase_polyket PF04673.12 ORY85942.1 - 0.012 15.8 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Polyketide synthesis cyclase Methyltransf_4 PF02390.17 ORY85942.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Sacchrp_dh_C PF16653.5 ORY85943.1 - 2.6e-75 253.9 0.0 4.2e-75 253.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY85943.1 - 2.3e-21 76.4 0.1 6.1e-21 75.0 0.1 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_N PF05222.15 ORY85943.1 - 1.7e-19 70.4 0.0 4.3e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 ORY85943.1 - 6.5e-09 35.4 0.6 6e-05 22.4 0.0 3.5 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 ORY85943.1 - 2.1e-05 24.6 0.0 6.2e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 ORY85943.1 - 0.00065 19.6 0.4 0.0018 18.2 0.4 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 ORY85943.1 - 0.042 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.25 ORY85944.1 - 2.3e-65 220.6 0.0 3e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY85944.1 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY85944.1 - 2.3e-05 23.5 0.0 3.2e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY85944.1 - 0.00035 20.6 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY85944.1 - 0.00089 18.7 0.1 0.0025 17.2 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY85944.1 - 0.0092 15.3 0.0 0.047 13.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 ORY85944.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY85944.1 - 0.033 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DHquinase_II PF01220.19 ORY85945.1 - 3.8e-48 162.7 0.1 4.5e-48 162.4 0.1 1.1 1 0 0 1 1 1 1 Dehydroquinase class II FBD PF08387.10 ORY85947.1 - 0.068 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 FBD Gly_transf_sug PF04488.15 ORY85949.1 - 6.6e-09 36.3 0.0 1.2e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif LCAT PF02450.15 ORY85950.1 - 5.3e-06 25.9 0.0 8.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ORY85950.1 - 2.3e-05 25.1 0.5 7.6e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY85950.1 - 0.0021 17.4 0.1 0.0046 16.3 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY85950.1 - 0.013 15.1 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold SPX PF03105.19 ORY85950.1 - 0.12 12.2 6.9 1.9 8.3 4.2 2.2 2 0 0 2 2 2 0 SPX domain Ser_hydrolase PF06821.13 ORY85950.1 - 0.13 12.1 0.0 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase SMN PF06003.12 ORY85953.1 - 2.7 7.2 7.0 13 5.0 7.0 2.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zn_clus PF00172.18 ORY85954.1 - 0.00023 21.2 14.0 0.0004 20.4 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY85954.1 - 0.0015 17.6 0.5 0.0024 16.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain muHD PF10291.9 ORY85956.1 - 9.3e-48 163.0 0.1 1.3e-47 162.5 0.1 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 ORY85956.1 - 1.6e-07 31.5 0.3 1.6e-07 31.5 0.3 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain YscO PF07321.12 ORY85956.1 - 0.16 11.9 2.0 0.33 10.9 2.0 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO TMPIT PF07851.13 ORY85956.1 - 0.34 10.1 0.3 0.49 9.6 0.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein SRP9-21 PF05486.12 ORY85956.1 - 0.36 11.2 2.3 0.5 10.8 0.0 2.4 3 0 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) Cupin_2 PF07883.11 ORY85957.1 - 2.7e-07 30.2 0.3 6e-07 29.1 0.1 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 ORY85957.1 - 0.033 13.8 0.0 0.089 12.4 0.0 1.7 1 1 0 2 2 2 0 Cupin Cupin_2 PF07883.11 ORY85958.1 - 2.3e-08 33.6 0.2 1.1e-07 31.4 0.1 2.1 3 0 0 3 3 3 1 Cupin domain AraC_binding PF02311.19 ORY85958.1 - 0.00057 19.8 0.0 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain MannoseP_isomer PF01050.18 ORY85958.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Cupin_6 PF12852.7 ORY85958.1 - 0.09 12.5 0.0 0.17 11.6 0.0 1.5 1 1 0 1 1 1 0 Cupin Cupin_1 PF00190.22 ORY85958.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin UDG PF03167.19 ORY85959.1 - 7.9e-09 35.7 0.0 3.6e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Amidohydro_1 PF01979.20 ORY85960.1 - 1.9e-15 57.0 0.0 2.4e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY85960.1 - 7.3e-05 22.4 0.0 0.0003 20.4 0.0 1.9 2 0 0 2 2 2 1 Amidohydrolase family Glucosamine_iso PF01182.20 ORY85961.1 - 2.6e-14 53.6 0.0 1.8e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase BcrAD_BadFG PF01869.20 ORY85962.1 - 1.7e-14 54.0 0.0 2.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 ORY85962.1 - 0.065 12.8 0.0 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain UNC-93 PF05978.16 ORY85963.1 - 2.3e-12 46.9 6.3 2.3e-12 46.9 6.3 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORY85963.1 - 1e-11 44.4 42.6 1e-11 44.4 42.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY85963.1 - 0.002 17.0 7.8 0.002 17.0 7.8 2.8 2 1 1 3 3 3 2 MFS_1 like family Wzy_C_2 PF11846.8 ORY85963.1 - 0.79 9.6 5.0 0.2 11.5 0.9 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Sdh_cyt PF01127.22 ORY85963.1 - 3.1 7.8 10.0 0.61 10.1 0.8 3.5 3 1 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Methyltransf_10 PF05971.12 ORY85965.1 - 3.6e-68 230.1 0.0 5.1e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 ORY85965.1 - 1.1e-07 31.6 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 ORY85965.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 ORY85965.1 - 0.00041 21.0 0.0 0.00081 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY85965.1 - 0.0011 18.5 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TrmK PF04816.12 ORY85965.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_31 PF13847.6 ORY85965.1 - 0.0049 16.7 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY85965.1 - 0.0052 17.4 0.0 0.0097 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY85965.1 - 0.0083 16.1 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PTPS PF01242.19 ORY85966.1 - 4.3e-14 52.5 0.0 5.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DSPc PF00782.20 ORY85967.1 - 4e-29 101.1 0.0 4.7e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 ORY85967.1 - 0.0019 18.2 0.1 0.0085 16.1 0.1 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY85967.1 - 0.0024 17.5 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 ORY85967.1 - 0.0046 16.5 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 ORY85967.1 - 0.0053 17.0 0.0 0.0065 16.8 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain VHS PF00790.19 ORY85968.1 - 2.3e-17 63.2 0.0 4.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 ORY85968.1 - 4.2e-06 27.0 0.0 2.1e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 GAT domain HSP70 PF00012.20 ORY85970.1 - 1.1e-78 265.0 15.5 1.2e-77 261.6 0.9 3.5 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 ORY85970.1 - 0.0011 17.8 3.2 0.0037 16.1 0.0 2.8 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.16 ORY85970.1 - 0.0023 17.7 1.4 0.0072 16.1 0.1 2.3 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 ORY85970.1 - 0.039 13.5 0.2 0.083 12.4 0.2 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HMG_box PF00505.19 ORY85971.1 - 4.9e-25 87.7 4.0 9.4e-25 86.8 4.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY85971.1 - 1.4e-17 64.0 2.5 1.4e-17 64.0 2.5 2.3 2 1 1 3 3 3 1 HMG-box domain CHDNT PF08073.12 ORY85971.1 - 1.5e-05 24.9 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.6 ORY85971.1 - 4.6e-05 23.3 2.1 8.9e-05 22.4 2.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 RR_TM4-6 PF06459.12 ORY85971.1 - 2 8.2 13.3 2.7 7.8 13.3 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 YABBY PF04690.13 ORY85971.1 - 5.9 7.4 5.6 1.3 9.6 0.8 1.9 1 1 0 2 2 2 0 YABBY protein Oxysterol_BP PF01237.18 ORY85972.1 - 1.2e-58 198.7 0.0 3.7e-56 190.6 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein MOZ_SAS PF01853.18 ORY85972.1 - 0.14 11.8 0.0 4 7.1 0.0 2.1 1 1 1 2 2 2 0 MOZ/SAS family Membr_traf_MHD PF10540.9 ORY85973.1 - 1.1e-18 67.9 0.0 8.9e-16 58.4 0.0 2.6 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 ORY85973.1 - 4.2e-08 33.4 0.0 1.2e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 ORY85973.1 - 0.00024 19.8 1.7 0.00068 18.3 0.1 2.0 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) AAA PF00004.29 ORY85974.1 - 2.4e-59 199.5 0.0 1.2e-44 152.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY85974.1 - 4.2e-10 40.3 1.7 0.0077 16.6 0.0 4.4 4 1 0 4 4 3 2 AAA ATPase domain AAA_5 PF07728.14 ORY85974.1 - 6.9e-07 29.4 0.1 0.031 14.3 0.0 3.0 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORY85974.1 - 2.2e-06 27.9 0.0 0.031 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 ORY85974.1 - 1.2e-05 25.0 7.6 0.00049 19.9 0.3 2.9 3 0 0 3 3 2 2 AAA+ lid domain AAA_18 PF13238.6 ORY85974.1 - 1.9e-05 25.2 0.0 0.03 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ORY85974.1 - 0.00021 21.3 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 ORY85974.1 - 0.00023 21.0 0.0 0.0042 16.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 ORY85974.1 - 0.0006 19.5 0.0 1.3 8.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 ORY85974.1 - 0.0014 18.7 0.0 0.64 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY85974.1 - 0.0015 18.8 1.1 0.024 14.9 0.1 3.1 2 2 1 3 3 3 1 AAA domain Vps4_C PF09336.10 ORY85974.1 - 0.0017 18.3 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 ORY85974.1 - 0.0019 17.8 0.1 0.012 15.2 0.1 2.4 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 ORY85974.1 - 0.0019 17.4 0.0 0.033 13.4 0.0 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain DUF815 PF05673.13 ORY85974.1 - 0.002 17.3 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_2 PF07724.14 ORY85974.1 - 0.0033 17.6 0.0 0.018 15.2 0.0 2.3 3 1 0 3 3 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ORY85974.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 ORY85974.1 - 0.0057 16.0 0.2 0.013 14.9 0.0 1.6 2 0 0 2 2 1 1 KaiC RNA_helicase PF00910.22 ORY85974.1 - 0.0066 16.8 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 ORY85974.1 - 0.008 16.1 0.2 3.8 7.4 0.1 2.8 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 ORY85974.1 - 0.011 15.2 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORY85974.1 - 0.013 14.8 0.4 0.048 13.0 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 ORY85974.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 ORY85974.1 - 0.027 14.9 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY85974.1 - 0.028 13.6 0.0 5.3 6.1 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_28 PF13521.6 ORY85974.1 - 0.038 14.2 0.0 0.53 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY85974.1 - 0.048 13.4 0.1 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 ORY85974.1 - 0.063 13.1 0.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 ORY85974.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein SKI PF01202.22 ORY85974.1 - 0.084 13.0 0.1 5.6 7.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 ORY85974.1 - 0.13 12.0 1.3 13 5.5 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase AAA_30 PF13604.6 ORY85974.1 - 0.28 10.9 2.5 5.5 6.7 0.1 3.4 4 0 0 4 4 4 0 AAA domain BLOC1S3 PF15753.5 ORY85974.1 - 1.5 8.9 4.9 4 7.5 0.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 TauD PF02668.16 ORY85975.1 - 9.8e-26 91.1 0.0 1.7e-25 90.3 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Uricase PF01014.18 ORY85976.1 - 6.2e-65 217.4 0.9 3e-32 111.6 0.1 2.0 2 0 0 2 2 2 2 Uricase RNA_pol_I_A49 PF06870.12 ORY85977.1 - 1.2e-90 304.2 0.0 1.4e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SET PF00856.28 ORY85978.1 - 5e-21 75.8 0.4 1.4e-19 71.1 0.0 2.7 2 0 0 2 2 2 1 SET domain SRI PF08236.11 ORY85978.1 - 1.2e-17 63.9 5.1 2.8e-17 62.7 5.1 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 ORY85978.1 - 2.2e-13 50.0 11.5 2.2e-13 50.0 11.5 1.8 2 0 0 2 2 2 1 AWS domain WW PF00397.26 ORY85978.1 - 9e-07 28.9 0.5 1.8e-06 27.9 0.5 1.5 1 0 0 1 1 1 1 WW domain UNC-93 PF05978.16 ORY85979.1 - 2.3e-12 46.9 6.3 2.3e-12 46.9 6.3 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORY85979.1 - 1.3e-11 44.0 42.1 1.3e-11 44.0 42.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY85979.1 - 0.0034 16.3 8.8 0.0034 16.3 8.8 2.4 2 0 0 2 2 2 2 MFS_1 like family Wzy_C_2 PF11846.8 ORY85979.1 - 0.67 9.8 4.8 0.2 11.5 0.9 2.1 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Sdh_cyt PF01127.22 ORY85979.1 - 3.5 7.7 10.2 0.59 10.2 0.8 3.5 3 1 1 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit BcrAD_BadFG PF01869.20 ORY85980.1 - 3.3e-14 53.0 0.0 5.7e-14 52.2 0.0 1.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 ORY85980.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Glucosamine_iso PF01182.20 ORY85981.1 - 1.5e-21 77.4 0.0 2.1e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Amidohydro_1 PF01979.20 ORY85982.1 - 2.3e-14 53.5 0.0 3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY85982.1 - 0.00011 21.8 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Gp_dh_C PF02800.20 ORY85983.1 - 7.9e-70 233.5 0.1 1.1e-69 233.0 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORY85983.1 - 1.9e-34 118.0 0.2 4.5e-34 116.8 0.2 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 ORY85983.1 - 0.23 11.6 1.6 0.48 10.6 0.0 2.2 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Zn_clus PF00172.18 ORY85984.1 - 0.00011 22.3 8.5 0.00018 21.5 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SQS_PSY PF00494.19 ORY85986.1 - 5.9e-41 140.7 0.0 7.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ldh_1_N PF00056.23 ORY85988.1 - 8e-46 155.6 0.1 1.1e-45 155.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORY85988.1 - 8.5e-40 136.4 0.0 1.2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 ORY85988.1 - 0.0071 15.4 0.0 0.013 14.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 ORY85988.1 - 0.065 12.8 0.2 0.33 10.5 0.1 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.24 ORY85988.1 - 0.072 13.5 0.1 0.26 11.7 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 ORY85988.1 - 0.15 12.0 0.3 0.41 10.5 0.3 1.8 1 1 0 1 1 1 0 NAD(P)H-binding Lon_C PF05362.13 ORY85989.1 - 5e-68 228.7 0.3 8.5e-68 227.9 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 ORY85989.1 - 1.5e-22 80.4 0.0 3.3e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 ORY85989.1 - 3.1e-16 59.9 0.0 5.5e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 ORY85989.1 - 2.1e-10 40.7 0.0 6e-10 39.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORY85989.1 - 3.7e-08 33.2 0.1 8.7e-08 32.0 0.0 1.7 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 ORY85989.1 - 5e-06 26.8 0.6 0.0004 20.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY85989.1 - 6.4e-05 23.4 2.6 9.6e-05 22.8 0.0 2.6 3 2 0 3 3 2 1 AAA ATPase domain AAA_3 PF07726.11 ORY85989.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 ORY85989.1 - 0.00068 19.8 0.0 0.0026 17.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORY85989.1 - 0.0012 19.4 0.1 0.0062 17.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY85989.1 - 0.0028 17.8 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY85989.1 - 0.0031 17.3 0.0 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 ORY85989.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 ORY85989.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PGA2 PF07543.12 ORY85989.1 - 0.008 16.2 0.8 0.008 16.2 0.8 1.7 2 0 0 2 2 1 1 Protein trafficking PGA2 AAA_23 PF13476.6 ORY85989.1 - 0.018 15.6 0.4 0.46 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY85989.1 - 0.028 14.8 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 ORY85989.1 - 0.03 13.6 0.2 0.078 12.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 ORY85989.1 - 0.036 13.5 0.0 0.096 12.1 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.21 ORY85989.1 - 0.046 13.1 0.1 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORY85989.1 - 0.051 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY85989.1 - 0.07 12.8 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 ORY85989.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 ORY85989.1 - 0.13 12.5 0.1 0.43 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 ORY85989.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY85989.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 ORY85989.1 - 0.17 11.6 0.3 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY85989.1 - 0.22 10.6 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sulfotransfer_1 PF00685.27 ORY85990.1 - 0.27 10.7 0.8 0.39 10.1 0.8 1.1 1 0 0 1 1 1 0 Sulfotransferase domain NTP_transf_2 PF01909.23 ORY85991.1 - 2e-07 31.2 0.0 3.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY85991.1 - 0.0055 16.8 0.0 0.009 16.1 0.0 1.3 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Pan3_PK PF18101.1 ORY85992.1 - 4.4e-43 146.6 0.0 6.6e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain DUF543 PF04418.12 ORY85993.1 - 0.069 13.1 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Metallophos PF00149.28 ORY85994.1 - 2.2e-36 126.3 0.0 2.8e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 ORY85994.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain STPPase_N PF16891.5 ORY85994.1 - 0.071 13.6 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain LSM PF01423.22 ORY85995.1 - 1.3e-19 69.6 0.0 1.6e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 ORY85995.1 - 0.047 13.8 0.0 0.086 13.0 0.0 1.4 1 0 0 1 1 1 0 RimP C-terminal SH3 domain FoP_duplication PF13865.6 ORY85995.1 - 0.47 11.0 11.0 0.76 10.4 11.0 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 HEAT PF02985.22 ORY85996.1 - 3.4e-24 82.8 9.9 2.7e-05 24.1 0.0 10.4 10 1 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.6 ORY85996.1 - 2.3e-21 75.9 17.4 1.8e-13 50.6 0.1 9.0 8 3 3 11 11 10 3 HEAT-like repeat HEAT_2 PF13646.6 ORY85996.1 - 1.2e-10 41.6 17.1 0.0001 22.6 0.0 8.1 3 2 6 9 9 9 4 HEAT repeats Arm PF00514.23 ORY85996.1 - 3.8e-10 39.5 10.9 0.015 15.3 0.0 8.2 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 ORY85996.1 - 8.5e-10 38.4 1.4 2.7e-07 30.4 0.6 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 ORY85996.1 - 2.6e-05 24.3 0.0 0.00058 19.9 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 ORY85996.1 - 0.00031 20.5 3.9 5 6.8 0.0 5.2 5 1 0 5 5 5 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 ORY85996.1 - 0.0007 20.1 0.1 14 6.3 0.0 5.5 6 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 ORY85996.1 - 0.0035 16.5 4.8 0.97 8.5 0.8 4.5 4 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 ORY85996.1 - 0.0053 16.4 0.1 4.5 6.8 0.0 4.1 3 2 1 4 4 4 1 CLASP N terminal TRI12 PF06609.13 ORY85996.1 - 0.1 11.0 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DRIM PF07539.12 ORY85996.1 - 0.1 10.9 0.6 20 3.3 0.0 3.9 3 1 0 4 4 4 0 Down-regulated in metastasis MMS19_C PF12460.8 ORY85996.1 - 0.14 11.3 5.4 3.2 6.8 0.0 4.3 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal Pkinase PF00069.25 ORY85997.1 - 6.5e-73 245.3 1.1 7.3e-73 245.2 0.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY85997.1 - 5e-52 176.7 0.9 1.3e-51 175.3 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 ORY85997.1 - 1.1e-22 80.2 0.0 2.2e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORY85997.1 - 1.7e-13 51.0 0.5 3.4e-13 50.0 0.5 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORY85997.1 - 1.8e-06 27.5 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY85997.1 - 8.5e-06 24.8 0.0 1.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PH_11 PF15413.6 ORY85997.1 - 3.3e-05 24.2 0.5 0.00026 21.4 0.3 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain Haspin_kinase PF12330.8 ORY85997.1 - 0.0013 17.7 0.1 0.0022 17.0 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY85997.1 - 0.0016 18.5 0.1 0.004 17.1 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY85997.1 - 0.095 11.7 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ACT_3 PF10000.9 ORY85998.1 - 0.043 13.7 0.0 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY85998.1 - 0.13 12.0 0.0 0.74 9.6 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain ACT_3 PF10000.9 ORY85999.1 - 0.018 15.0 0.0 1 9.3 0.0 2.1 1 1 1 2 2 2 0 ACT domain PI3K_p85B PF02192.16 ORY85999.1 - 0.057 13.2 0.0 0.43 10.3 0.0 1.9 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain RNA_pol_Rpa2_4 PF06883.12 ORY85999.1 - 0.15 12.1 0.0 10 6.2 0.0 2.0 1 1 1 2 2 2 0 RNA polymerase I, Rpa2 specific domain DNA_pol_B_palm PF14792.6 ORY86000.1 - 3.6e-20 72.3 0.0 6.9e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ORY86000.1 - 1.6e-13 50.6 0.0 3.4e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ORY86000.1 - 4.4e-11 42.4 0.0 1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda EAP30 PF04157.16 ORY86000.1 - 0.061 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family Pribosyltran PF00156.27 ORY86001.1 - 1.4e-13 50.7 0.4 2.3e-13 50.0 0.4 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Cullin_binding PF03556.15 ORY86002.1 - 8.2e-35 119.9 1.9 1.3e-34 119.3 1.9 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 ORY86002.1 - 5.3e-10 38.9 0.3 1.3e-09 37.8 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain RMF PF04957.12 ORY86002.1 - 0.023 14.9 0.2 0.05 13.8 0.2 1.5 1 0 0 1 1 1 0 Ribosome modulation factor SNase PF00565.17 ORY86003.1 - 7.9e-26 90.7 0.0 1.1e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue SRP9-21 PF05486.12 ORY86004.1 - 3.7e-12 46.5 0.5 1.6e-10 41.2 0.5 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) RRM_1 PF00076.22 ORY86005.1 - 1.4e-61 204.2 0.0 7.8e-17 60.9 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY86005.1 - 2.6e-06 27.1 0.0 0.043 13.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY86005.1 - 1.7e-05 24.6 0.0 0.18 11.6 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 ORY86005.1 - 0.0076 16.1 0.4 12 5.7 0.0 3.4 3 0 0 3 3 3 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 ORY86005.1 - 0.04 14.0 0.0 2.7 8.2 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY86005.1 - 0.052 13.5 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Plant_tran PF04827.14 ORY86005.1 - 0.084 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Plant transposon protein RRM_2 PF04059.12 ORY86005.1 - 0.23 11.7 0.0 15 5.8 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif 2 PHM7_cyt PF14703.6 ORY86005.1 - 0.23 11.7 1.3 46 4.2 0.0 3.9 3 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Prefoldin PF02996.17 ORY86006.1 - 5.5e-26 90.8 0.9 7.6e-26 90.4 0.3 1.5 1 1 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.11 ORY86006.1 - 0.011 16.1 0.6 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3287 PF11690.8 ORY86006.1 - 0.044 13.5 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Syntaxin-6_N PF09177.11 ORY86006.1 - 0.047 14.2 6.5 1.3 9.6 0.7 2.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal COG2 PF06148.11 ORY86006.1 - 0.079 13.1 3.4 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BCAS3 PF12490.8 ORY86006.1 - 0.088 12.3 1.5 0.12 11.9 1.2 1.4 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 3 Lebercilin PF15619.6 ORY86006.1 - 0.15 11.7 4.9 3.5 7.2 1.1 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IES5 PF17335.2 ORY86006.1 - 0.3 11.4 3.1 1.6 9.0 0.3 2.1 2 0 0 2 2 2 0 Ino80 complex subunit 5 PEMT PF04191.13 ORY86007.1 - 7.1e-52 174.3 17.3 8.3e-32 109.7 2.3 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 ORY86007.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 ORY86007.1 - 0.024 15.2 0.1 0.24 12.0 0.1 2.4 1 1 0 1 1 1 0 SKICH domain Ribosomal_S16 PF00886.19 ORY86008.1 - 4.1e-13 49.2 0.0 7.4e-13 48.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S16 GPP34 PF05719.11 ORY86008.1 - 0.14 12.2 0.2 0.19 11.8 0.2 1.2 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) WD40 PF00400.32 ORY86009.1 - 3.9e-09 37.0 1.9 0.092 13.7 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_alt PF14077.6 ORY86009.1 - 0.1 12.5 0.2 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif Mito_fiss_reg PF05308.11 ORY86009.1 - 0.17 12.0 0.1 0.17 12.0 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Vps36_ESCRT-II PF11605.8 ORY86010.1 - 5e-19 68.3 0.0 7.4e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 ORY86010.1 - 7.1e-17 61.5 0.0 9.8e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family GRAM PF02893.20 ORY86010.1 - 0.0041 17.0 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Vps36-NZF-N PF16988.5 ORY86010.1 - 0.022 14.2 6.8 0.049 13.0 1.4 2.7 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 ORY86010.1 - 0.053 13.6 5.0 1.2 9.2 0.1 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DZR PF12773.7 ORY86010.1 - 2.1 8.4 4.5 3.7 7.7 0.5 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.18 ORY86010.1 - 3.4 7.1 13.1 6.9 6.1 3.2 2.7 2 1 1 3 3 3 0 Zn-finger in Ran binding protein and others MarR_2 PF12802.7 ORY86011.1 - 0.01 15.7 0.4 0.54 10.2 0.0 3.8 4 0 0 4 4 4 0 MarR family B-block_TFIIIC PF04182.12 ORY86011.1 - 0.011 15.9 0.2 0.57 10.4 0.0 3.5 4 0 0 4 4 4 0 B-block binding subunit of TFIIIC HTH_IclR PF09339.10 ORY86011.1 - 2.3 8.1 4.3 14 5.6 0.1 3.7 4 0 0 4 4 4 0 IclR helix-turn-helix domain Methyltransf_11 PF08241.12 ORY86013.1 - 1.1e-10 42.1 0.0 2.4e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY86013.1 - 7.8e-10 39.3 0.0 3.1e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY86013.1 - 8.9e-10 38.6 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY86013.1 - 0.002 18.0 0.0 0.018 14.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY86013.1 - 0.0083 15.5 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family OTU PF02338.19 ORY86016.1 - 1.8e-10 41.4 0.0 3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY86016.1 - 0.13 11.7 0.0 4.9 6.5 0.1 2.2 1 1 1 2 2 2 0 Peptidase C65 Otubain BAR PF03114.18 ORY86017.1 - 4.2e-07 29.9 1.8 6.5e-07 29.2 1.8 1.3 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 ORY86017.1 - 2.6e-06 27.2 0.0 5.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY86017.1 - 1.8e-05 24.3 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY86017.1 - 5.7e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF5129 PF17173.4 ORY86017.1 - 0.032 13.4 1.0 0.053 12.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) DUF4407 PF14362.6 ORY86017.1 - 0.42 9.9 2.6 0.71 9.2 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-T_C PF15511.6 ORY86018.1 - 0.16 12.1 0.2 0.32 11.1 0.0 1.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold zf-C2H2 PF00096.26 ORY86019.1 - 4.3e-09 36.3 18.8 0.0023 18.3 4.1 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY86019.1 - 4e-07 30.3 19.9 0.00099 19.8 0.2 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY86019.1 - 1.2e-06 28.6 16.2 1.4e-06 28.5 1.4 4.5 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY86019.1 - 0.0031 17.7 10.5 0.019 15.2 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY86019.1 - 0.0091 16.0 0.7 0.0091 16.0 0.7 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 ORY86019.1 - 0.28 11.8 3.1 1.9 9.2 0.0 2.7 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 ORY86019.1 - 2.9 8.4 13.9 0.64 10.5 0.4 4.6 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Pyr_redox_2 PF07992.14 ORY86020.1 - 1.8e-40 139.0 0.0 2.4e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY86020.1 - 5.2e-09 36.5 0.1 1.5e-05 25.5 0.0 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 ORY86020.1 - 2e-07 30.9 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_9 PF13454.6 ORY86020.1 - 0.019 15.0 0.9 8.9 6.3 0.0 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORY86020.1 - 0.064 12.4 0.0 3.2 6.8 0.0 2.9 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 ORY86020.1 - 0.32 9.7 0.4 4.3 5.9 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein SNF2_N PF00176.23 ORY86023.1 - 2.7e-49 167.8 0.0 4.5e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY86023.1 - 2.4e-18 66.5 0.0 5.4e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY86023.1 - 1.1e-06 28.8 0.0 1.1e-05 25.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY86023.1 - 6.3e-05 22.8 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase VIGSSK PF14773.6 ORY86023.1 - 0.0004 20.4 0.7 0.002 18.2 0.7 2.3 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal SWI2_SNF2 PF18766.1 ORY86023.1 - 0.00078 19.2 0.3 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 ORY86023.1 - 0.024 13.9 0.1 0.058 12.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_pol_Rpb2_6 PF00562.28 ORY86026.1 - 3.4e-128 428.0 0.2 5.6e-128 427.3 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY86026.1 - 9.5e-58 195.1 0.1 1.4e-57 194.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ORY86026.1 - 1.4e-34 118.4 0.6 3.6e-34 117.0 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ORY86026.1 - 5.5e-32 110.9 0.2 1.2e-31 109.9 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 ORY86026.1 - 2e-26 92.1 1.2 4.7e-26 90.8 1.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 ORY86026.1 - 4e-19 68.6 0.0 8.7e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ORY86026.1 - 4.6e-09 36.7 1.4 4.6e-09 36.7 1.4 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Diphthami_syn_2 PF01902.17 ORY86027.1 - 2.1e-31 109.1 0.0 2.5e-24 86.0 0.0 2.4 2 0 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 ORY86027.1 - 1.2e-09 38.2 0.0 0.0025 17.8 0.0 3.9 4 0 0 4 4 4 2 Endoribonuclease L-PSP Dus PF01207.17 ORY86028.1 - 3.1e-54 184.2 0.0 1.3e-46 159.2 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DHDPS PF00701.22 ORY86028.1 - 0.095 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family Sugar_tr PF00083.24 ORY86029.1 - 1.2e-97 327.7 16.5 1.3e-97 327.5 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY86029.1 - 8.3e-15 54.6 25.7 8.3e-15 54.6 25.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily EBP PF05241.12 ORY86029.1 - 0.062 12.8 1.3 0.2 11.1 1.0 2.0 1 1 0 1 1 1 0 Emopamil binding protein Polysacc_deac_1 PF01522.21 ORY86031.1 - 0.0029 17.5 0.1 0.009 15.9 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide deacetylase Ribosomal_L28e PF01778.17 ORY86032.1 - 8.9e-21 74.8 0.0 1.2e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Glyco_hydro_18 PF00704.28 ORY86033.1 - 1e-58 199.6 1.6 1.3e-58 199.2 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_1c PF00749.21 ORY86037.1 - 1.4e-104 349.4 0.0 1.9e-104 349.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ORY86037.1 - 3.8e-37 127.8 0.0 6.3e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 ORY86037.1 - 0.0096 16.1 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY86037.1 - 0.08 13.0 0.2 0.18 11.8 0.2 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 ORY86037.1 - 0.11 11.9 0.2 0.32 10.3 0.2 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF5427 PF10310.9 ORY86038.1 - 0.17 10.8 2.2 0.18 10.7 2.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) RNase_PH PF01138.21 ORY86039.1 - 3.8e-14 53.3 0.3 6.4e-14 52.6 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 ACOX PF01756.19 ORY86040.1 - 1.6e-28 99.5 0.0 3.6e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORY86040.1 - 1e-21 77.8 0.1 2.6e-21 76.5 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORY86040.1 - 2.5e-09 37.2 0.0 6.2e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORY86040.1 - 0.023 14.9 0.3 0.25 11.6 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY86040.1 - 0.048 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Kazal_1 PF00050.21 ORY86041.1 - 0.29 11.2 2.6 0.57 10.2 2.6 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain TraD_N PF12615.8 ORY86041.1 - 1.5 9.7 9.9 13 6.7 2.3 4.0 3 1 0 3 3 3 0 F sex factor protein N terminal CinA_KH PF18146.1 ORY86041.1 - 1.9 8.7 4.9 0.77 10.0 0.9 2.1 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Taq-exonuc PF09281.10 ORY86041.1 - 5.8 6.9 7.7 3.2 7.8 1.0 2.3 2 0 0 2 2 2 0 Taq polymerase, exonuclease RRM_1 PF00076.22 ORY86043.1 - 7.1e-20 70.6 0.0 8.9e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY86043.1 - 0.00021 20.9 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 ORY86044.1 - 2e-47 161.8 0.0 2.9e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY86044.1 - 1.5e-43 149.0 0.0 3.8e-43 147.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY86044.1 - 0.0007 18.5 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY86044.1 - 0.023 14.1 0.0 0.048 13.0 0.0 1.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY86044.1 - 0.04 12.9 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain MRC1 PF09444.10 ORY86044.1 - 1.1 9.7 6.6 0.19 12.2 0.3 2.3 2 0 0 2 2 2 0 MRC1-like domain Methyltransf_4 PF02390.17 ORY86047.1 - 2.1e-47 160.8 0.0 6e-35 120.2 0.0 2.6 3 0 0 3 3 3 2 Putative methyltransferase Methyltransf_25 PF13649.6 ORY86047.1 - 0.0018 18.9 0.0 0.15 12.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY86047.1 - 0.0075 16.9 0.0 4 8.1 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 ORY86047.1 - 0.0091 15.6 0.0 0.45 10.0 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORY86047.1 - 0.15 11.9 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_deac_1 PF01522.21 ORY86050.1 - 7.9e-29 100.1 0.1 1.4e-28 99.3 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY86050.1 - 0.00017 20.9 0.0 0.00024 20.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 PPR_2 PF13041.6 ORY86051.1 - 3.1e-10 40.1 0.0 1e-05 25.6 0.0 4.4 4 1 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 ORY86051.1 - 0.015 15.4 0.0 16 5.7 0.1 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR PF01535.20 ORY86051.1 - 0.063 13.5 2.1 39 4.8 0.0 5.4 7 0 0 7 7 7 0 PPR repeat PPR_long PF17177.4 ORY86051.1 - 0.099 12.0 0.0 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP Cation_efflux PF01545.21 ORY86052.1 - 7.2e-30 104.2 5.8 1e-29 103.7 5.8 1.2 1 0 0 1 1 1 1 Cation efflux family MFS_MOT1 PF16983.5 ORY86052.1 - 0.045 14.1 0.6 0.045 14.1 0.6 2.4 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily MFS_1 PF07690.16 ORY86053.1 - 2.1e-12 46.6 18.3 2.1e-12 46.6 18.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY86053.1 - 0.007 15.3 2.4 0.007 15.3 2.4 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter Brr6_like_C_C PF10104.9 ORY86053.1 - 0.05 13.4 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain OATP PF03137.20 ORY86053.1 - 0.47 8.7 4.0 0.33 9.2 1.0 2.0 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family F-box-like PF12937.7 ORY86054.1 - 1.1e-05 25.2 0.1 3.9e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like RecC_C PF17946.1 ORY86054.1 - 0.042 13.6 0.2 0.29 10.9 0.4 2.0 2 0 0 2 2 2 0 RecC C-terminal domain FeoC PF09012.10 ORY86054.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator zf-Tim10_DDP PF02953.15 ORY86055.1 - 1.3e-23 82.3 0.1 1.9e-23 81.8 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 ORY86055.1 - 0.082 12.6 1.4 0.12 12.1 1.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF5435 PF17503.2 ORY86055.1 - 0.13 12.0 0.1 0.68 9.6 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5435) PhoLip_ATPase_C PF16212.5 ORY86056.1 - 2.4e-51 174.9 21.7 2.4e-51 174.9 21.7 2.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY86056.1 - 4.3e-18 64.7 3.3 9.4e-18 63.7 3.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 ORY86056.1 - 1.8e-15 56.9 0.0 1.1e-14 54.3 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY86056.1 - 2.9e-15 57.1 0.5 1.4e-09 38.6 0.5 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY86056.1 - 7.7e-09 35.5 0.0 8.9e-08 32.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY86056.1 - 0.0002 21.2 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Amidohydro_3 PF07969.11 ORY86060.1 - 1.4e-83 282.0 0.0 1.7e-83 281.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY86060.1 - 6.4e-17 61.9 0.0 2.1e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Pkinase PF00069.25 ORY86062.1 - 7.9e-45 153.3 0.0 5.2e-44 150.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY86062.1 - 5.9e-28 97.9 0.0 8.7e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY86062.1 - 0.00021 20.7 0.0 0.00091 18.6 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 ORY86062.1 - 0.058 12.4 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY86062.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY86062.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nucleo_P87 PF07267.11 ORY86062.1 - 0.64 8.8 8.2 1 8.2 8.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RNA_pol PF00940.19 ORY86063.1 - 2e-145 484.8 0.0 7.9e-140 466.3 0.0 2.1 2 0 0 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.6 ORY86063.1 - 1.7e-98 330.2 0.9 6.1e-98 328.3 0.1 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal DUF2111 PF09884.9 ORY86063.1 - 0.13 12.3 0.4 14 5.8 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) DUF3557 PF12078.8 ORY86067.1 - 0.025 14.6 0.1 0.045 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) Zn_Tnp_IS1595 PF12760.7 ORY86067.1 - 0.035 14.1 0.4 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Rad50_zn_hook PF04423.14 ORY86067.1 - 0.25 11.2 0.7 0.68 9.8 0.0 2.1 2 1 1 3 3 3 0 Rad50 zinc hook motif RRM_1 PF00076.22 ORY86068.1 - 1.7e-12 47.0 0.0 1e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY86068.1 - 0.016 14.8 0.0 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 ORY86072.1 - 2.9e-33 114.7 0.1 3.6e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY86072.1 - 8.1e-28 97.1 0.0 1e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY86072.1 - 2.4e-08 33.6 0.0 2.9e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY86072.1 - 8.8e-05 22.6 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY86072.1 - 0.00035 20.0 0.0 0.00042 19.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 ORY86072.1 - 0.0026 18.1 0.0 0.0029 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.20 ORY86072.1 - 0.0087 15.3 0.2 0.026 13.7 0.1 1.6 1 1 1 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 ORY86072.1 - 0.0098 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase CobA_CobO_BtuR PF02572.15 ORY86072.1 - 0.024 14.9 0.0 0.031 14.5 0.0 1.1 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TniB PF05621.11 ORY86072.1 - 0.027 13.9 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 ORY86072.1 - 0.061 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 ORY86072.1 - 0.094 12.0 0.0 0.095 12.0 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 ORY86072.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 ORY86072.1 - 0.14 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Hpr_kinase_C PF07475.12 ORY86072.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 1 1 2 2 2 0 HPr Serine kinase C-terminal domain CIA30 PF08547.12 ORY86629.1 - 2.4e-32 112.2 0.0 3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) ABC2_membrane_2 PF12679.7 ORY86632.1 - 0.009 15.3 0.8 0.009 15.3 0.8 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein 7tm_7 PF08395.12 ORY86632.1 - 1.6 7.9 13.1 0.4 9.8 5.0 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor MTABC_N PF16185.5 ORY86634.1 - 0.024 14.1 1.2 0.044 13.3 0.4 1.7 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region RTA1 PF04479.13 ORY86634.1 - 0.051 13.2 2.5 0.084 12.5 1.0 1.9 1 1 1 2 2 2 0 RTA1 like protein DUF4181 PF13789.6 ORY86634.1 - 0.21 11.9 3.0 6.3 7.1 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) DUF4551 PF15087.6 ORY86635.1 - 0.75 8.6 3.5 0.91 8.3 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Apt1 PF10351.9 ORY86635.1 - 3.6 6.3 6.4 4.2 6.1 6.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glyco_hydro_16 PF00722.21 ORY86636.1 - 0.00077 19.0 0.2 0.0017 17.9 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Secretin_N_2 PF07655.13 ORY86636.1 - 4.3 7.9 14.5 0.97 10.0 5.4 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain PI_PP_I PF18363.1 ORY86637.1 - 0.11 12.7 0.1 0.32 11.2 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain MAP65_ASE1 PF03999.12 ORY86637.1 - 0.25 10.0 4.7 0.32 9.7 4.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Sugar_tr PF00083.24 ORY86638.1 - 4.1e-25 88.6 19.2 2.6e-13 49.7 8.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter BT1 PF03092.16 ORY86638.1 - 0.99 7.5 6.2 1.8 6.7 0.2 2.2 2 0 0 2 2 2 0 BT1 family DUF4366 PF14283.6 ORY86639.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4307 PF14155.6 ORY86639.1 - 0.11 12.4 0.3 0.2 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) DUF2749 PF10907.8 ORY86639.1 - 0.18 12.0 3.1 0.17 12.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DPBB_1 PF03330.18 ORY86640.1 - 0.0017 18.6 0.1 0.043 14.1 0.0 2.0 2 0 0 2 2 2 2 Lytic transglycolase Glycoprotein PF03409.15 ORY86641.1 - 0.7 8.7 7.3 0.055 12.3 2.6 1.5 2 0 0 2 2 2 0 Transmembrane glycoprotein PhzC-PhzF PF02567.16 ORY86644.1 - 7e-50 170.1 0.0 8.5e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein ARID PF01388.21 ORY86645.1 - 8e-19 68.1 0.0 8e-19 68.1 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Med15_fungi PF05397.12 ORY86645.1 - 3.3e-18 66.0 0.2 3.3e-18 66.0 0.2 4.8 5 0 0 5 5 5 1 Mediator complex subunit 15 Sugar_tr PF00083.24 ORY86647.1 - 3.1e-98 329.6 23.9 3.9e-98 329.3 23.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY86647.1 - 8.4e-17 61.1 23.1 8.4e-17 61.1 23.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3021 PF11457.8 ORY86647.1 - 3.3 8.0 19.7 0.14 12.4 6.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3021) CH PF00307.31 ORY86649.1 - 7.1e-79 261.1 0.0 2.2e-18 66.4 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY86649.1 - 0.00028 20.6 0.0 0.22 11.4 0.0 3.9 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_7 PF13499.6 ORY86649.1 - 0.0023 18.4 0.0 0.029 14.8 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair INTS5_N PF14837.6 ORY86649.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus LRR_4 PF12799.7 ORY86650.1 - 0.0055 17.1 2.8 0.72 10.4 0.0 3.9 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY86650.1 - 0.17 12.0 0.1 14 6.0 0.0 3.7 5 0 0 5 5 5 0 Leucine Rich repeat NmrA PF05368.13 ORY86651.1 - 4.6e-29 101.6 0.0 5.5e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY86651.1 - 5e-10 39.6 0.0 8.5e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding SNARE_assoc PF09335.11 ORY86652.1 - 6e-16 59.0 4.5 1.6e-15 57.6 4.9 1.5 2 0 0 2 2 2 1 SNARE associated Golgi protein 2TM PF13239.6 ORY86652.1 - 0.0098 16.2 6.1 0.5 10.7 0.2 2.5 1 1 1 2 2 2 2 2TM domain BPD_transp_2 PF02653.16 ORY86652.1 - 0.036 13.2 5.6 0.065 12.4 5.6 1.3 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component IBR PF01485.21 ORY86653.1 - 2.4e-06 27.7 31.4 1.6e-05 25.0 7.1 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_14 PF17978.1 ORY86653.1 - 0.078 13.4 1.5 0.24 11.8 1.5 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CDP-OH_P_transf PF01066.21 ORY86654.1 - 3.8e-13 50.0 0.3 3.8e-13 50.0 0.3 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DPBB_1 PF03330.18 ORY86655.1 - 0.0043 17.3 0.0 0.012 15.9 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY86655.1 - 0.038 13.8 3.3 0.12 12.3 0.1 2.5 2 0 0 2 2 2 0 Barwin family DUF4064 PF13273.6 ORY86655.1 - 0.063 13.6 0.2 0.26 11.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) YL1 PF05764.13 ORY86655.1 - 0.66 10.0 11.5 1.7 8.7 11.5 1.6 1 0 0 1 1 1 0 YL1 nuclear protein NTP_transf_2 PF01909.23 ORY86656.1 - 2.4e-08 34.2 0.3 7.3e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 ORY86656.1 - 3.9e-06 27.0 0.4 1e-05 25.7 0.4 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 ORY86656.1 - 0.035 14.2 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase BCDHK_Adom3 PF10436.9 ORY86657.1 - 1.4e-31 109.5 0.0 2.1e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY86657.1 - 2.5e-08 34.4 0.0 8.7e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY86657.1 - 0.036 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sugar_tr PF00083.24 ORY86658.1 - 4.3e-14 52.2 0.0 5.3e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 ORY86659.1 - 4.6e-88 296.1 20.9 5.9e-88 295.7 20.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY86659.1 - 7.3e-12 44.9 29.8 7.3e-12 44.9 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DPBB_1 PF03330.18 ORY86660.1 - 2.5e-08 34.1 0.1 1.5e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 ORY86660.1 - 2.6e-06 27.2 6.5 0.0013 18.6 3.3 2.5 2 0 0 2 2 2 2 Barwin family Macoilin PF09726.9 ORY86660.1 - 2.8 6.4 13.8 4.2 5.8 13.8 1.2 1 0 0 1 1 1 0 Macoilin family SOBP PF15279.6 ORY86660.1 - 7.3 7.1 7.1 10 6.6 7.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein zf-MYND PF01753.18 ORY86661.1 - 5.1e-08 32.9 14.3 6.6e-08 32.5 14.3 1.2 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY86661.1 - 0.033 14.0 3.2 0.069 13.0 3.2 1.6 1 0 0 1 1 1 0 HIT zinc finger zinc_ribbon_2 PF13240.6 ORY86661.1 - 1.5 8.6 9.6 9.6 6.1 5.8 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 ORY86661.1 - 2.3 8.4 8.0 2.4 8.3 8.0 1.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_S15 PF02129.18 ORY86662.1 - 2.4e-36 125.7 0.0 2.4e-35 122.4 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ORY86662.1 - 4.4e-35 121.7 0.0 6e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FAA_hydrolase PF01557.18 ORY86663.1 - 1.7e-44 152.1 0.0 2.1e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 ORY86663.1 - 3.8e-23 81.7 0.0 6.1e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Peptidase_S15 PF02129.18 ORY86664.1 - 2.5e-40 138.8 0.3 3.4e-40 138.4 0.3 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ORY86664.1 - 6.1e-32 111.4 0.0 1e-31 110.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 ORY86664.1 - 0.0012 18.4 0.1 0.0021 17.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY86664.1 - 0.0014 17.9 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cupin_2 PF07883.11 ORY86665.1 - 9.9e-09 34.8 0.0 5e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Cupin domain TRI12 PF06609.13 ORY86666.1 - 1.9e-25 89.4 24.2 2.5e-25 89.0 24.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY86666.1 - 6.3e-13 48.4 49.3 6.3e-13 48.4 49.3 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily RRM_8 PF11835.8 ORY86666.1 - 0.086 13.1 1.2 0.41 10.9 0.3 2.4 2 1 1 3 3 3 0 RRM-like domain PhyH PF05721.13 ORY86667.1 - 1.1e-11 45.4 0.2 3.3e-10 40.6 0.2 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ORY86667.1 - 1.7e-07 30.4 0.1 0.011 14.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 ORY86667.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Cupin_2 PF07883.11 ORY86667.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Cupin domain FAD_binding_3 PF01494.19 ORY86668.1 - 2.4e-19 69.8 2.7 3.7e-18 65.9 2.7 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY86668.1 - 1.9e-08 33.9 0.1 3.6e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY86668.1 - 1.6e-07 31.2 0.2 6.1e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY86668.1 - 3.3e-05 24.0 0.2 7.3e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY86668.1 - 0.0001 21.5 1.3 0.00017 20.8 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORY86668.1 - 0.00015 20.9 0.2 0.00024 20.3 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORY86668.1 - 0.008 15.5 1.3 0.11 11.7 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY86668.1 - 0.012 15.0 0.7 0.025 13.9 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY86668.1 - 0.014 14.2 2.7 0.034 12.8 0.5 2.0 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 ORY86668.1 - 0.016 14.1 1.1 0.27 10.0 0.6 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.17 ORY86668.1 - 0.019 14.2 0.2 0.034 13.4 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Methyltransf_16 PF10294.9 ORY86668.1 - 0.024 14.4 0.1 0.055 13.2 0.1 1.5 2 0 0 2 2 2 0 Lysine methyltransferase Pyr_redox PF00070.27 ORY86668.1 - 0.027 15.0 1.2 0.093 13.3 1.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY86668.1 - 0.027 13.6 1.0 0.027 13.6 1.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ORY86668.1 - 0.035 14.1 1.2 4.4 7.3 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Potex_coat PF06184.11 ORY86668.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein FAD_oxidored PF12831.7 ORY86668.1 - 0.16 11.3 0.8 0.26 10.6 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase LigB PF02900.18 ORY86669.1 - 2e-15 56.6 0.0 2.5e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase AAA PF00004.29 ORY86670.1 - 2.5e-20 73.2 0.0 4.9e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY86670.1 - 8.1e-05 22.9 0.7 0.0019 18.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY86670.1 - 0.00017 22.0 0.8 0.00045 20.6 0.8 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ORY86670.1 - 0.0028 17.4 0.2 0.0058 16.4 0.2 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 ORY86670.1 - 0.0078 15.4 0.2 0.016 14.4 0.1 1.5 2 0 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 ORY86670.1 - 0.0084 16.1 0.1 0.022 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Torsin PF06309.11 ORY86670.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Torsin MeaB PF03308.16 ORY86670.1 - 0.017 14.1 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 ORY86670.1 - 0.02 15.2 0.3 0.037 14.4 0.3 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY86670.1 - 0.034 14.3 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY86670.1 - 0.065 13.5 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 ORY86671.1 - 6.3e-18 64.8 0.3 1.7e-17 63.3 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aldedh PF00171.22 ORY86673.1 - 7.3e-18 64.3 0.3 3.6e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family AMP-binding PF00501.28 ORY86674.1 - 1.7e-29 102.7 0.0 8.4e-29 100.4 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ORY86674.1 - 1.5e-07 31.2 1.7 1.5e-07 31.2 1.7 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ORY86674.1 - 0.0054 17.7 0.0 0.012 16.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 ORY86676.1 - 1.4e-07 31.5 8.3 2.7e-07 30.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 ORY86676.1 - 0.0016 18.4 0.8 0.033 14.2 0.1 2.3 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension ABC_tran_CTD PF16326.5 ORY86676.1 - 0.034 14.4 0.0 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF4038 PF13204.6 ORY86678.1 - 1.9e-81 274.1 0.0 2.3e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 ORY86678.1 - 5.3e-15 55.2 0.0 1.9e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 Putative collagen-binding domain of a collagenase ImmE5 PF11480.8 ORY86678.1 - 0.045 14.2 0.2 2.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Colicin-E5 Imm protein Sugar_tr PF00083.24 ORY86679.1 - 1.7e-99 333.7 18.6 2e-99 333.5 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY86679.1 - 3e-16 59.3 23.0 3e-16 59.3 23.0 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY86679.1 - 0.00039 19.1 3.8 0.00039 19.1 3.8 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein MASE2 PF05230.11 ORY86679.1 - 0.018 15.1 5.2 0.16 12.0 0.8 2.8 2 0 0 2 2 2 0 MASE2 domain Roughex PF06020.11 ORY86680.1 - 4.5 6.3 7.8 10 5.1 7.8 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Pirin PF02678.16 ORY86681.1 - 1.1e-27 96.1 0.2 1.7e-27 95.5 0.2 1.2 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 ORY86681.1 - 4.6e-05 23.0 0.0 0.0019 17.9 0.1 2.2 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 ORY86681.1 - 0.011 15.9 0.0 0.13 12.4 0.0 2.6 2 1 0 2 2 2 0 Quercetinase C-terminal cupin domain LRR19-TM PF15176.6 ORY86682.1 - 0.52 10.3 2.2 19 5.3 0.0 3.2 2 1 1 3 3 3 0 Leucine-rich repeat family 19 TM domain COX7C PF02935.16 ORY86684.1 - 1.1e-16 60.8 0.3 1.1e-16 60.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc HemX PF04375.14 ORY86685.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4307 PF14155.6 ORY86685.1 - 0.074 12.9 0.1 0.074 12.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF572 PF04502.13 ORY86687.1 - 3.3e-68 230.8 0.0 3.9e-68 230.5 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Forkhead PF00250.18 ORY86688.1 - 1e-09 38.5 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain SAP130_C PF16014.5 ORY86688.1 - 0.33 10.0 5.7 1.5 7.8 0.3 2.1 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus PHD PF00628.29 ORY86690.1 - 2.3e-05 24.2 8.1 2.3e-05 24.2 8.1 2.5 3 0 0 3 3 3 2 PHD-finger Forkhead PF00250.18 ORY86690.1 - 0.096 12.9 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Forkhead domain TMEM154 PF15102.6 ORY86691.1 - 0.7 9.8 0.0 0.7 9.8 0.0 2.9 3 1 0 3 3 3 0 TMEM154 protein family SKG6 PF08693.10 ORY86691.1 - 1.9 8.0 3.5 3.7 7.0 3.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain adh_short_C2 PF13561.6 ORY86692.1 - 1.9e-52 178.2 0.1 2.4e-52 177.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY86692.1 - 1.6e-33 115.9 0.2 2.2e-33 115.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY86692.1 - 2.7e-11 43.7 0.4 4.4e-11 43.0 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY86692.1 - 3.2e-05 23.5 0.2 8e-05 22.2 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY86692.1 - 0.0001 21.9 0.0 0.0099 15.3 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY86692.1 - 0.0025 16.8 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 ORY86692.1 - 0.0071 16.2 0.2 0.013 15.4 0.2 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans_2 PF11951.8 ORY86693.1 - 4.5e-18 65.2 0.0 6.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY86693.1 - 0.00041 20.4 13.4 0.00084 19.4 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 ORY86694.1 - 2.2e-20 72.8 0.0 3.1e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 ORY86695.1 - 1.7e-23 83.1 35.7 1.5e-22 80.1 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAT PF03417.16 ORY86696.1 - 1.4e-31 109.9 0.0 2e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Polysacc_deac_1 PF01522.21 ORY86697.1 - 1.3e-09 38.0 0.0 6.9e-08 32.4 0.0 2.6 1 1 1 2 2 2 1 Polysaccharide deacetylase NUDIX PF00293.28 ORY86697.1 - 0.01 15.9 0.3 5.1 7.1 0.1 2.6 2 1 0 2 2 2 0 NUDIX domain DUF2334 PF10096.9 ORY86697.1 - 0.042 13.5 0.1 0.11 12.1 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) NIF PF03031.18 ORY86699.1 - 1.7e-48 164.3 0.0 2.4e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribonuc_L-PSP PF01042.21 ORY86700.1 - 2.3e-05 24.4 0.0 2.9e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAP PF00956.18 ORY86702.1 - 3.7e-16 59.1 0.2 7.1e-16 58.2 0.1 1.5 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Pkinase PF00069.25 ORY86703.1 - 5.5e-55 186.6 0.0 6.8e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY86703.1 - 2.5e-26 92.5 0.0 3.2e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY86703.1 - 3.1e-08 33.3 0.0 4.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY86703.1 - 0.013 15.5 0.1 0.068 13.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY86703.1 - 0.11 11.5 0.0 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Hydrolase_4 PF12146.8 ORY86705.1 - 7.3e-18 64.7 0.0 1.3e-10 41.0 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY86705.1 - 7.5e-10 38.9 0.0 5.6e-07 29.5 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY86705.1 - 6.7e-07 30.1 0.0 1.1e-06 29.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORY86705.1 - 2.5e-05 24.3 0.0 0.00022 21.2 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 ORY86705.1 - 3.5e-05 22.7 0.0 0.0019 17.0 0.0 2.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 ORY86705.1 - 0.00017 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 ORY86705.1 - 0.00045 19.8 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ORY86705.1 - 0.0012 18.4 0.0 0.0079 15.8 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family LIDHydrolase PF10230.9 ORY86705.1 - 0.0079 15.8 0.0 0.049 13.2 0.0 1.9 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 ORY86705.1 - 0.0089 15.9 0.0 0.041 13.8 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF818 PF05677.12 ORY86705.1 - 0.022 13.7 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 ORY86705.1 - 0.024 14.4 0.5 0.23 11.3 0.1 2.2 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 ORY86705.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Anoctamin PF04547.12 ORY86706.1 - 9e-105 351.1 3.9 1.1e-104 350.8 3.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF4870 PF09685.10 ORY86706.1 - 0.024 14.8 1.9 0.18 12.0 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4870) Peroxidase_2 PF01328.17 ORY86707.1 - 4.2e-32 112.2 0.0 5.3e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 zf-MYND PF01753.18 ORY86708.1 - 1.1e-09 38.2 9.9 1.9e-09 37.4 9.9 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY86708.1 - 0.00084 19.4 5.3 0.0019 18.2 5.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DNA_pol_A_exo1 PF01612.20 ORY86709.1 - 5e-07 29.6 0.0 9.5e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease RabGAP-TBC PF00566.18 ORY86710.1 - 1.9e-34 119.2 3.4 3.4e-34 118.4 3.4 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 ORY86710.1 - 2.7e-07 30.2 0.0 3.5e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Rab-binding domain (RBD) FAD_binding_2 PF00890.24 ORY86711.1 - 2.2e-85 287.3 1.1 3.4e-85 286.6 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 ORY86711.1 - 1.4e-20 73.2 0.0 3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 ORY86711.1 - 1.6e-15 57.5 0.4 2.8e-15 56.7 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY86711.1 - 3e-11 43.4 2.9 1.6e-10 41.0 0.3 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY86711.1 - 2.8e-10 39.9 0.4 9e-10 38.2 0.3 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY86711.1 - 2.6e-09 37.0 0.9 5.4e-09 35.9 0.9 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY86711.1 - 3.6e-07 29.2 1.9 0.00011 21.1 0.1 3.0 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.17 ORY86711.1 - 6e-06 25.7 1.1 0.0026 17.0 0.3 2.7 2 1 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 ORY86711.1 - 9.3e-06 25.1 0.0 0.0086 15.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY86711.1 - 1.7e-05 24.2 0.1 2.4e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ORY86711.1 - 0.00011 21.4 2.2 0.0038 16.4 0.9 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY86711.1 - 0.00037 19.9 1.2 0.00091 18.6 0.6 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ORY86711.1 - 0.00083 18.8 0.1 0.0033 16.8 0.1 2.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ORY86711.1 - 0.00092 19.2 0.3 0.35 10.9 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORY86711.1 - 0.0015 19.1 1.8 0.012 16.1 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 ORY86711.1 - 0.041 12.4 0.0 0.07 11.6 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.12 ORY86711.1 - 0.072 12.1 0.3 0.14 11.2 0.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 ORY86711.1 - 0.073 13.5 0.1 0.16 12.4 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 ORY86711.1 - 0.1 12.9 0.2 0.28 11.4 0.1 1.9 2 0 0 2 2 1 0 TrkA-N domain TauD PF02668.16 ORY86712.1 - 1.9e-42 145.9 0.8 2.4e-42 145.6 0.8 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CAP PF00188.26 ORY86713.1 - 3.9e-20 73.0 0.1 3.9e-20 73.0 0.1 2.0 2 1 0 2 2 2 1 Cysteine-rich secretory protein family SOG2 PF10428.9 ORY86713.1 - 0.069 12.3 8.2 0.08 12.1 8.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CBM_14 PF01607.24 ORY86713.1 - 3.4 7.9 8.2 9.9 6.4 0.1 2.8 2 2 0 2 2 2 0 Chitin binding Peritrophin-A domain LRR_4 PF12799.7 ORY86714.1 - 0.027 14.9 2.9 10 6.7 0.1 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 ORY86715.1 - 4.1e-87 290.7 16.0 6.3e-45 153.0 2.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY86715.1 - 3.1e-69 233.1 10.4 1.1e-35 123.4 1.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY86715.1 - 7.2e-33 114.0 8.5 1.2e-16 61.2 0.8 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 ORY86715.1 - 5.2e-32 110.0 0.0 1.2e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 ORY86715.1 - 0.00019 21.6 0.0 0.041 14.0 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.18 ORY86715.1 - 0.0005 20.0 7.2 0.074 12.9 1.6 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltr_RsmB-F PF01189.17 ORY86715.1 - 0.0011 18.7 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F 2-Hacid_dh_C PF02826.19 ORY86715.1 - 0.019 14.3 0.3 0.091 12.1 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 ORY86715.1 - 0.065 13.3 4.4 1.3 9.1 0.6 2.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORY86715.1 - 0.12 13.1 0.8 3.9 8.3 0.2 2.6 2 0 0 2 2 2 0 Methyltransferase domain Mur_ligase_C PF02875.21 ORY86715.1 - 0.17 12.2 0.0 12 6.2 0.0 3.5 4 0 0 4 4 3 0 Mur ligase family, glutamate ligase domain DUF543 PF04418.12 ORY86715.1 - 0.97 9.5 5.0 7.7 6.6 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF543) CBP4 PF07960.11 ORY86718.1 - 2.7e-12 46.7 0.0 3.2e-12 46.4 0.0 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 ORY86718.1 - 0.00013 21.8 0.1 0.0002 21.2 0.1 1.4 1 1 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 BESS PF02944.20 ORY86718.1 - 0.078 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 BESS motif NYN PF01936.18 ORY86719.1 - 4.1e-24 85.8 0.0 4.9e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 NYN domain Peroxidase_2 PF01328.17 ORY86722.1 - 7.9e-28 98.3 0.0 9.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 PG_binding_3 PF09374.10 ORY86722.1 - 0.15 12.3 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Predicted Peptidoglycan domain zf-MYND PF01753.18 ORY86723.1 - 3.7e-09 36.5 11.8 6.7e-09 35.7 11.8 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY86723.1 - 0.005 16.9 6.6 0.016 15.3 6.6 1.8 1 1 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DnaB_C PF03796.15 ORY86723.1 - 0.036 13.4 0.2 0.05 12.9 0.2 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain SurE PF01975.17 ORY86724.1 - 9.7e-49 165.8 0.0 1.2e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Glyco_trans_4_4 PF13579.6 ORY86724.1 - 0.035 14.6 0.0 0.052 14.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 ORY86724.1 - 0.041 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 DUF1295 PF06966.12 ORY86725.1 - 5.8e-33 114.4 4.7 9.4e-31 107.1 0.9 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1295) Serinc PF03348.15 ORY86725.1 - 0.0014 17.6 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) HATPase_c PF02518.26 ORY86726.1 - 1e-49 167.7 0.0 5.8e-25 88.0 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY86726.1 - 4.9e-41 139.4 0.0 9.9e-21 74.0 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 ORY86726.1 - 4e-23 81.2 2.8 1.2e-13 50.9 0.3 3.3 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY86726.1 - 7.2e-12 45.5 0.0 5.9e-05 23.3 0.0 3.0 2 0 0 2 2 2 2 PAS fold HATPase_c_3 PF13589.6 ORY86726.1 - 1.1e-07 31.7 0.1 0.0034 17.2 0.0 2.9 3 0 0 3 3 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 ORY86726.1 - 1.9e-05 24.5 0.0 0.00062 19.7 0.0 3.1 3 0 0 3 3 3 1 PAS domain PAS_9 PF13426.7 ORY86726.1 - 0.00027 21.2 0.0 0.0076 16.5 0.0 3.3 3 0 0 3 3 3 1 PAS domain GAF_2 PF13185.6 ORY86726.1 - 0.0056 17.0 0.0 0.038 14.3 0.0 2.5 3 0 0 3 3 3 1 GAF domain Kdo_hydroxy PF11004.8 ORY86726.1 - 0.01 15.1 0.0 0.29 10.4 0.0 2.3 2 0 0 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase PAS_3 PF08447.12 ORY86726.1 - 0.023 15.0 0.0 0.066 13.5 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAS PF00989.25 ORY86726.1 - 0.033 14.2 0.0 0.15 12.1 0.0 2.2 2 1 0 2 2 2 0 PAS fold BUD22 PF09073.10 ORY86726.1 - 0.15 11.4 35.2 0.093 12.1 3.8 2.7 2 0 0 2 2 2 0 BUD22 HATPase_c PF02518.26 ORY86727.1 - 9.4e-50 167.8 0.0 1.1e-23 83.9 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY86727.1 - 4.7e-41 139.5 0.1 2.2e-23 82.5 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 ORY86727.1 - 8.2e-20 70.6 3.8 5.6e-12 45.5 0.4 3.0 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY86727.1 - 2.2e-09 37.5 0.1 7.7e-05 22.9 0.1 2.8 2 0 0 2 2 2 2 PAS fold HATPase_c_3 PF13589.6 ORY86727.1 - 1.8e-05 24.6 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 ORY86727.1 - 0.00013 22.3 0.1 0.00076 19.8 0.0 2.3 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.12 ORY86727.1 - 0.0006 20.1 0.0 0.0032 17.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 ORY86727.1 - 0.0056 16.7 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 ORY86727.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold HATPase_c_2 PF13581.6 ORY86727.1 - 0.011 15.7 0.0 0.59 10.1 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain GAF_3 PF13492.6 ORY86727.1 - 0.019 15.3 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 GAF domain PAS_9 PF13426.7 ORY86727.1 - 0.1 12.9 0.0 0.32 11.3 0.0 1.9 2 0 0 2 2 2 0 PAS domain DUF2917 PF11142.8 ORY86727.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) Mg_chelatase_C PF13335.6 ORY86727.1 - 0.48 11.1 4.9 1.2 9.8 1.2 2.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Aconitase PF00330.20 ORY86728.1 - 5.4e-160 533.4 0.3 6.5e-160 533.1 0.3 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY86728.1 - 3.2e-34 118.1 0.0 5.7e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Sulfatase PF00884.23 ORY86729.1 - 4.2e-54 184.0 0.2 5.1e-54 183.7 0.2 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 ORY86729.1 - 0.008 14.8 0.0 0.012 14.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4976 PF16347.5 ORY86729.1 - 0.034 14.4 0.0 0.078 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) ParBc PF02195.18 ORY86729.1 - 0.044 14.1 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 ParB-like nuclease domain zf-MYND PF01753.18 ORY86730.1 - 1.6e-08 34.5 9.3 1.6e-08 34.5 9.3 1.6 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 ORY86730.1 - 0.0015 18.6 5.7 0.0033 17.5 5.7 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 ORY86730.1 - 0.4 10.6 3.1 0.97 9.4 3.1 1.7 1 0 0 1 1 1 0 HIT zinc finger ADH_N_2 PF16884.5 ORY86731.1 - 5.3e-21 74.5 0.1 2e-20 72.7 0.1 1.9 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORY86731.1 - 6.2e-20 71.5 0.7 1.1e-19 70.7 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY86731.1 - 2.4e-07 31.8 0.0 6.5e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 ORY86731.1 - 0.0012 18.4 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 ORY86731.1 - 0.048 13.1 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAAA-beta PF15508.6 ORY86731.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase rve_2 PF13333.6 ORY86732.1 - 0.0025 18.0 0.7 20 5.4 0.1 3.2 3 0 0 3 3 3 1 Integrase core domain Ribosom_S12_S23 PF00164.25 ORY86732.1 - 0.0038 16.8 0.0 15 5.2 0.0 3.1 3 0 0 3 3 3 2 Ribosomal protein S12/S23 HypF_C PF17788.1 ORY86732.1 - 0.01 16.5 3.7 14 6.4 0.1 3.2 3 0 0 3 3 3 0 HypF Kae1-like domain ECSCR PF15820.5 ORY86732.1 - 0.027 14.3 0.0 45 3.9 0.0 3.2 3 0 0 3 3 3 0 Endothelial cell-specific chemotaxis regulator zinc-ribbon_6 PF10005.9 ORY86732.1 - 0.035 14.8 1.4 77 4.1 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain DUF4337 PF14235.6 ORY86732.1 - 0.13 12.4 0.0 1e+02 2.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Tetrabrachion PF11401.8 ORY86732.1 - 0.28 11.2 0.0 96 3.1 0.0 2.9 3 0 0 3 3 3 0 Tetrabrachion Herpes_glycoH_C PF17488.2 ORY86732.1 - 0.34 10.7 1.5 22 4.9 0.0 2.9 3 0 0 3 3 3 0 Herpesvirus glycoprotein H C-terminal domain Phage_integrase PF00589.22 ORY86733.1 - 5.2e-05 23.1 0.0 5.3e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Phage integrase family Rad21_Rec8_N PF04825.13 ORY86735.1 - 1.7e-27 95.8 0.0 2.8e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 ORY86735.1 - 4.3e-12 45.1 0.0 1.3e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF3807 PF12720.7 ORY86735.1 - 0.011 16.1 0.5 0.011 16.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SMC_ScpA PF02616.14 ORY86735.1 - 0.051 13.5 0.0 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Segregation and condensation protein ScpA zf-MYND PF01753.18 ORY86737.1 - 7.5e-11 41.9 11.7 1.4e-10 41.1 11.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY86737.1 - 0.084 13.0 5.3 0.2 11.8 5.3 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_ligase_OB_2 PF14743.6 ORY86738.1 - 1.5e-26 92.2 0.0 3.4e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 ORY86738.1 - 1.1e-12 48.1 0.0 1.7e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 ORY86738.1 - 0.00064 20.1 0.0 0.0012 19.1 0.0 1.5 1 1 0 1 1 1 1 RNA ligase SWIM PF04434.17 ORY86738.1 - 0.17 11.6 0.8 0.35 10.6 0.8 1.5 1 0 0 1 1 1 0 SWIM zinc finger DUF3619 PF12279.8 ORY86739.1 - 0.015 15.6 0.1 0.033 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Herpes_capsid PF06112.11 ORY86739.1 - 0.25 11.4 10.4 0.58 10.2 10.4 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF4551 PF15087.6 ORY86739.1 - 0.48 9.2 3.6 0.61 8.9 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) IBR PF01485.21 ORY86740.1 - 3.7e-16 59.1 32.8 1.8e-09 37.7 2.9 3.6 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 ORY86740.1 - 3.9e-09 36.8 0.0 2.5e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 RWD domain zf-C3HC4 PF00097.25 ORY86740.1 - 0.00031 20.5 5.9 0.00031 20.5 5.9 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY86740.1 - 0.00053 20.3 6.2 0.00053 20.3 6.2 3.8 3 1 0 3 3 3 2 Ring finger domain zf-RING_5 PF14634.6 ORY86740.1 - 0.00086 19.2 8.6 0.00086 19.2 8.6 3.9 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY86740.1 - 0.01 15.8 9.0 0.01 15.8 9.0 3.7 3 0 0 3 3 3 0 RING-type zinc-finger PQ-loop PF04193.14 ORY86741.1 - 2.9e-26 91.0 8.4 4e-14 52.1 0.1 2.9 3 0 0 3 3 3 2 PQ loop repeat MFS_1 PF07690.16 ORY86742.1 - 5.7e-41 140.6 59.0 5e-40 137.5 53.7 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY86742.1 - 2.2e-07 30.1 14.4 2.2e-07 30.1 14.4 3.3 3 2 1 4 4 4 1 Sugar (and other) transporter zf-MYND PF01753.18 ORY86743.1 - 3.4e-08 33.4 10.7 6.2e-08 32.6 10.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY86743.1 - 0.037 14.1 4.1 0.1 12.7 4.1 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 ORY86745.1 - 4.6e-08 33.0 11.7 8.5e-08 32.2 11.7 1.5 1 0 0 1 1 1 1 MYND finger DNA_ligase_OB_2 PF14743.6 ORY86746.1 - 3.5e-25 87.8 0.0 6.3e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 ORY86746.1 - 4.9e-13 49.2 0.0 1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 ORY86746.1 - 0.0004 20.7 0.0 0.00079 19.8 0.0 1.5 1 1 0 1 1 1 1 RNA ligase SWIM PF04434.17 ORY86746.1 - 0.11 12.2 0.5 0.21 11.3 0.5 1.5 1 0 0 1 1 1 0 SWIM zinc finger CCER1 PF15482.6 ORY86746.1 - 4.2 7.2 7.2 0.87 9.4 0.9 2.6 3 0 0 3 3 3 0 Coiled-coil domain-containing glutamate-rich protein family 1 Sen15 PF09631.10 ORY86747.1 - 1.1e-16 60.9 0.0 1.3e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 Sen15 protein Autophagy_N PF03986.13 ORY86748.1 - 8.6e-43 145.6 0.0 1.4e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 ORY86748.1 - 2e-17 63.5 0.7 3.8e-17 62.6 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 ORY86748.1 - 9.2e-15 53.9 0.7 1.7e-14 53.0 0.7 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-MYND PF01753.18 ORY86749.1 - 2.2e-10 40.5 12.7 5e-10 39.3 12.7 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY86749.1 - 1.2e-05 25.3 2.6 2.2e-05 24.5 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Pex24p PF06398.11 ORY86750.1 - 1.8e-34 119.3 0.0 3.9e-34 118.2 0.0 1.5 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-MYND PF01753.18 ORY86750.1 - 1.9e-07 31.1 13.7 3.3e-07 30.3 13.7 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY86750.1 - 0.0015 18.6 4.4 0.0033 17.5 4.4 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Shisa PF13908.6 ORY86750.1 - 0.35 11.1 3.4 0.9 9.7 3.4 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator K_oxygenase PF13434.6 ORY86751.1 - 2.8e-11 43.1 0.1 9.3e-08 31.6 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY86751.1 - 4.1e-09 36.1 0.2 1e-05 25.0 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY86751.1 - 5.1e-09 36.2 1.5 5.4e-05 22.9 0.1 3.5 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY86751.1 - 1.3e-08 35.0 0.0 2.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY86751.1 - 1.5e-08 34.3 0.0 0.00026 20.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY86751.1 - 2.2e-06 27.7 0.3 0.0025 17.8 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding FMO-like PF00743.19 ORY86751.1 - 1.2e-05 24.0 0.0 0.00031 19.3 0.0 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like GIDA PF01134.22 ORY86751.1 - 0.017 14.2 0.3 0.84 8.6 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 ORY86751.1 - 0.029 13.6 0.2 0.36 10.0 0.0 2.5 3 0 0 3 3 3 0 Thi4 family Amino_oxidase PF01593.24 ORY86751.1 - 0.066 12.5 0.0 0.3 10.3 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase MFS_1 PF07690.16 ORY86752.1 - 3e-27 95.5 43.4 1.1e-16 60.8 17.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY86752.1 - 1.6e-19 70.1 11.6 1.6e-17 63.5 0.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 ORY86752.1 - 1.3e-06 28.0 20.4 0.0035 16.7 10.4 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ORY86752.1 - 2.3e-05 22.9 0.3 0.0051 15.2 0.0 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family UPF0126 PF03458.13 ORY86752.1 - 0.014 15.3 1.9 0.014 15.3 1.9 2.9 3 0 0 3 3 3 0 UPF0126 domain pEK499_p136 PF18736.1 ORY86752.1 - 0.044 13.4 0.1 7 6.2 0.0 2.7 3 0 0 3 3 3 0 HEPN pEK499 p136 MFS_1_like PF12832.7 ORY86752.1 - 0.2 10.4 9.6 0.052 12.4 6.3 1.8 1 1 1 2 2 2 0 MFS_1 like family DNA_pol_phi PF04931.13 ORY86752.1 - 3.1 5.8 3.3 4.8 5.2 3.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 ORY86753.1 - 5.1e-66 222.7 0.0 4.7e-34 117.9 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.7 ORY86753.1 - 3e-44 151.5 0.2 3e-44 151.5 0.2 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.17 ORY86753.1 - 3.6e-33 114.9 0.0 1.5e-17 63.8 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 ORY86753.1 - 6.2e-18 65.2 0.1 1.2e-17 64.3 0.1 1.5 1 0 0 1 1 1 1 RWD domain Kinase-like PF14531.6 ORY86753.1 - 2e-05 24.1 0.0 0.0038 16.6 0.0 2.6 2 0 0 2 2 2 2 Kinase-like HGTP_anticodon PF03129.20 ORY86753.1 - 0.0091 16.1 1.4 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain Kdo PF06293.14 ORY86753.1 - 0.014 14.7 0.0 2.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UQ_con PF00179.26 ORY86753.1 - 0.15 11.7 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Presenilin PF01080.17 ORY86753.1 - 0.44 9.3 5.2 0.95 8.2 5.2 1.4 1 0 0 1 1 1 0 Presenilin JmjC PF02373.22 ORY86754.1 - 1.2e-13 51.4 0.0 2.8e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase FYVE PF01363.21 ORY86754.1 - 0.65 10.2 6.6 2.4 8.4 6.6 1.9 1 0 0 1 1 1 0 FYVE zinc finger zf-C5HC2 PF02928.16 ORY86754.1 - 1.4 9.3 6.2 3.6 8.1 6.2 1.7 1 0 0 1 1 1 0 C5HC2 zinc finger F-box-like PF12937.7 ORY86755.1 - 0.00038 20.3 0.4 0.00086 19.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY86755.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain zf-MYND PF01753.18 ORY86757.1 - 2.2e-10 40.4 12.5 5.1e-10 39.3 12.5 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY86757.1 - 5.5e-05 23.2 3.0 9.7e-05 22.4 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_L36 PF00444.18 ORY86758.1 - 2.2e-16 59.8 6.0 2.2e-16 59.8 6.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L36 DUF3398 PF11878.8 ORY86758.1 - 0.21 12.1 0.1 0.4 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Molybdopterin PF00384.22 ORY86759.1 - 5.3e-65 220.1 0.0 9.2e-64 216.0 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 ORY86759.1 - 2.1e-18 66.1 0.8 1.3e-17 63.6 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 ORY86759.1 - 1.6e-17 62.7 0.2 1.6e-17 62.7 0.2 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 ORY86759.1 - 4.4e-13 49.7 0.0 1.2e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 ORY86759.1 - 5.2e-08 32.7 0.4 5.2e-08 32.7 0.4 2.5 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ORY86759.1 - 0.02 14.6 0.0 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 ORY86759.1 - 0.22 11.4 1.3 5.9 6.9 0.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Peroxidase_2 PF01328.17 ORY86760.1 - 6.5e-08 33.3 0.0 7.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Glyco_transf_15 PF01793.16 ORY87380.1 - 2.1e-34 119.2 0.5 2.3e-34 119.1 0.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase gpUL132 PF11359.8 ORY87380.1 - 0.032 13.8 0.1 0.036 13.6 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 Glyco_transf_15 PF01793.16 ORY87381.1 - 0.041 13.1 0.0 0.045 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase AA_permease PF00324.21 ORY87382.1 - 2.7e-109 365.9 37.9 3.3e-109 365.6 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY87382.1 - 3.3e-21 75.6 42.0 4.1e-21 75.3 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease Brix PF04427.18 ORY87383.1 - 1.3e-39 136.3 0.0 1.7e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Brix domain TPT PF03151.16 ORY87384.1 - 2.6e-17 63.1 6.8 3.1e-17 62.9 6.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY87384.1 - 5.3e-06 26.6 12.1 5.3e-06 26.6 12.1 2.0 2 1 0 2 2 2 1 EamA-like transporter family UAA PF08449.11 ORY87384.1 - 0.00027 20.2 5.1 0.00047 19.5 5.1 1.5 1 1 0 1 1 1 1 UAA transporter family Bystin PF05291.11 ORY87384.1 - 0.02 14.2 0.4 0.028 13.7 0.4 1.3 1 0 0 1 1 1 0 Bystin Glyco_hydro_cc PF11790.8 ORY87385.1 - 4.2e-58 196.7 0.8 5.7e-58 196.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Transp_inhibit PF18791.1 ORY87385.1 - 0.011 15.2 0.1 0.034 13.7 0.1 1.8 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain FSA_C PF10479.9 ORY87385.1 - 1.8 6.6 17.4 2.5 6.1 17.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus MAP65_ASE1 PF03999.12 ORY87385.1 - 4.3 5.9 8.3 5.6 5.5 8.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Glyco_hydro_cc PF11790.8 ORY87386.1 - 1.1e-63 215.0 2.2 1.5e-63 214.6 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core YobH PF13996.6 ORY87386.1 - 0.032 14.3 0.1 0.07 13.2 0.1 1.5 1 0 0 1 1 1 0 YobH-like protein DUF733 PF05306.11 ORY87386.1 - 0.25 11.6 1.4 0.54 10.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF733) FRQ PF09421.10 ORY87386.1 - 0.32 9.0 5.9 0.56 8.2 5.9 1.3 1 0 0 1 1 1 0 Frequency clock protein Seryl_tRNA_N PF02403.22 ORY87386.1 - 0.63 10.3 5.2 1.2 9.4 5.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PAF PF15715.5 ORY87386.1 - 3.4 8.3 6.1 7.2 7.2 6.1 1.5 1 0 0 1 1 1 0 PCNA-associated factor histone like domain ABM PF03992.16 ORY87387.1 - 0.049 13.7 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 ORY87388.1 - 1.4e-10 40.6 15.2 4.3e-10 39.1 14.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY87388.1 - 9e-05 21.9 2.9 0.00014 21.3 2.9 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2556 PF10831.8 ORY87388.1 - 0.12 12.3 0.6 0.21 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) DUF2530 PF10745.9 ORY87388.1 - 0.26 11.6 6.4 1.2 9.4 1.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 ORY87390.1 - 2.6e-51 174.6 66.9 2.3e-40 138.6 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY87390.1 - 8e-15 54.3 25.4 3.1e-09 35.9 0.9 4.0 3 1 1 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.24 ORY87390.1 - 9.5e-11 41.2 25.5 2.9e-06 26.4 13.0 4.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORY87390.1 - 5.7e-09 35.3 19.3 7e-06 25.1 7.2 2.4 1 1 1 2 2 2 2 MFS_1 like family OATP PF03137.20 ORY87390.1 - 0.00042 18.7 21.3 0.0015 16.9 2.3 4.2 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family DUF1270 PF06900.11 ORY87390.1 - 0.94 9.9 4.3 0.69 10.3 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) Put_Phosphatase PF06888.12 ORY87391.1 - 1.2e-51 175.4 0.0 1.3e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 ORY87391.1 - 5.5e-05 23.6 0.3 0.00023 21.6 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase FKBP_C PF00254.28 ORY87392.1 - 5.8e-30 103.5 0.1 1.3e-29 102.4 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 ORY87392.1 - 1e-13 51.7 0.2 2.6e-13 50.4 0.2 1.7 1 0 0 1 1 1 1 Nucleoplasmin-like domain TFIIF_alpha PF05793.12 ORY87392.1 - 0.015 13.9 23.5 0.0048 15.6 14.9 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 ORY87392.1 - 0.016 14.7 19.1 0.011 15.1 11.8 2.1 2 0 0 2 2 2 0 SDA1 CENP-B_dimeris PF09026.10 ORY87392.1 - 0.025 14.9 1.8 0.025 14.9 1.8 3.1 2 1 1 3 3 3 0 Centromere protein B dimerisation domain DUF3246 PF11596.8 ORY87392.1 - 2 7.8 8.3 0.36 10.2 1.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3246) PAC1 PF16094.5 ORY87392.1 - 5.3 6.1 7.9 0.22 10.7 1.2 1.8 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 PGM_PMM_I PF02878.16 ORY87393.1 - 1.2e-35 122.2 0.1 4.8e-35 120.3 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ORY87393.1 - 4.4e-21 75.4 0.0 1.4e-20 73.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 ORY87393.1 - 1.1e-14 54.7 0.1 1.9e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 ORY87393.1 - 2.1e-06 27.8 0.1 8.9e-06 25.8 0.1 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RasGEF PF00617.19 ORY87394.1 - 2.9e-60 203.5 0.0 5.1e-60 202.7 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY87394.1 - 8.2e-24 83.9 0.0 2e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 ORY87394.1 - 8.4e-14 50.9 1.8 9.5e-13 47.5 0.0 2.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORY87394.1 - 1e-09 38.1 2.8 8e-09 35.2 0.0 2.7 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 ORY87394.1 - 2e-09 37.0 1.0 1.7e-08 34.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 ORY87394.1 - 2.6e-05 24.2 8.6 0.0018 18.3 0.1 2.9 3 0 0 3 3 3 2 WW domain An_peroxidase PF03098.15 ORY87395.1 - 4.5e-31 108.0 0.0 1.8e-20 73.0 0.0 4.0 1 1 1 2 2 2 2 Animal haem peroxidase WLM PF08325.10 ORY87396.1 - 5.2e-28 98.4 0.0 6.3e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 ORY87396.1 - 2.4e-07 31.0 0.3 4.7e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 ORY87396.1 - 0.02 14.8 0.3 0.051 13.4 0.1 1.8 2 1 0 2 2 2 0 SprT-like family ANTH PF07651.16 ORY87398.1 - 1.6e-47 161.8 0.4 2.2e-47 161.4 0.4 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 ORY87398.1 - 3.9e-06 26.9 0.0 7.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.11 ORY87398.1 - 0.0014 19.0 31.5 0.0014 19.0 31.5 8.9 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) Ion_trans_N PF08412.10 ORY87398.1 - 0.012 15.1 0.5 0.039 13.6 0.5 1.9 1 0 0 1 1 1 0 Ion transport protein N-terminal SCA7 PF08313.12 ORY87399.1 - 7e-28 96.3 0.1 7e-28 96.3 0.1 1.6 2 0 0 2 2 2 1 SCA7, zinc-binding domain SIR2 PF02146.17 ORY87400.1 - 1.4e-32 113.1 0.0 3.3e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 Sir2 family CpXC PF14353.6 ORY87400.1 - 0.065 13.3 0.0 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 CpXC protein Phg_2220_C PF09524.10 ORY87400.1 - 0.085 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) DUF1325 PF07039.11 ORY87402.1 - 5.5e-33 113.8 0.0 7.8e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain Taxilin PF09728.9 ORY87402.1 - 0.17 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein SPX PF03105.19 ORY87402.1 - 0.24 11.3 2.6 0.27 11.1 2.6 1.2 1 0 0 1 1 1 0 SPX domain zf-met2 PF12907.7 ORY87403.1 - 4.4e-11 42.7 2.1 5.8e-11 42.3 2.1 1.2 1 0 0 1 1 1 1 Zinc-binding Aldo_ket_red PF00248.21 ORY87404.1 - 4.5e-65 219.8 0.0 5.3e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2334 PF10096.9 ORY87404.1 - 0.08 12.6 0.4 0.2 11.3 0.1 1.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) PTCB-BRCT PF12738.7 ORY87405.1 - 2.4e-25 88.3 1.1 6.2e-14 51.7 0.1 4.0 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 ORY87405.1 - 1e-22 80.3 0.0 3.7e-10 40.0 0.0 6.1 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY87405.1 - 8.4e-18 64.6 0.0 0.036 14.5 0.0 6.3 6 1 0 6 6 6 4 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 ORY87405.1 - 2.8e-17 62.4 0.0 1.2e-16 60.4 0.0 2.1 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 ORY87405.1 - 5.8e-05 23.3 0.0 16 5.8 0.0 5.2 5 1 0 5 5 5 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 ORY87405.1 - 0.28 11.3 1.5 1 9.4 0.0 2.7 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain Ndc80_HEC PF03801.13 ORY87406.1 - 4.2e-33 114.2 0.0 8.7e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 ORY87406.1 - 0.014 15.5 0.1 0.014 15.5 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF5595) Exonuc_VII_L PF02601.15 ORY87406.1 - 0.38 10.3 13.0 2 7.9 0.9 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4200 PF13863.6 ORY87406.1 - 3.1 8.2 36.8 0.092 13.1 1.4 4.1 3 1 2 5 5 5 0 Domain of unknown function (DUF4200) Tubulin PF00091.25 ORY87407.1 - 3e-64 216.9 0.0 5.5e-64 216.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY87407.1 - 4.3e-38 130.3 0.0 6.5e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY87407.1 - 0.00088 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY87407.1 - 0.005 16.6 0.0 0.0084 15.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain DIOX_N PF14226.6 ORY87409.1 - 5.2e-15 56.2 0.0 8.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY87409.1 - 1.8e-14 54.0 0.0 3.3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DcpS_C PF11969.8 ORY87410.1 - 1.3e-26 93.3 0.1 2.8e-26 92.2 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 ORY87410.1 - 9.4e-24 84.3 0.0 1.5e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal RSN1_TM PF13967.6 ORY87411.1 - 0.027 14.2 1.5 1.5 8.6 0.1 2.2 1 1 1 2 2 2 0 Late exocytosis, associated with Golgi transport 7tm_3 PF00003.22 ORY87411.1 - 2.2 7.9 8.6 6 6.5 6.4 2.3 2 1 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Ribosomal_L16 PF00252.18 ORY87412.1 - 4.4e-41 140.0 0.5 6.2e-41 139.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L16p/L10e Mito_carr PF00153.27 ORY87413.1 - 1.7e-57 191.3 0.0 8.9e-22 76.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pyrid_ox_like PF16242.5 ORY87414.1 - 1.7e-27 95.8 0.1 2.4e-27 95.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 ORY87414.1 - 2.7e-11 43.5 0.0 6.4e-11 42.3 0.0 1.5 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase TPR_11 PF13414.6 ORY87415.1 - 0.0013 18.3 1.6 0.22 11.2 0.2 2.8 2 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 ORY87415.1 - 0.0084 15.9 0.7 9.5 6.2 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY87415.1 - 0.02 15.1 0.1 6.5 7.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY87415.1 - 0.1 12.7 1.4 21 5.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY87415.1 - 6.3 7.2 7.2 26 5.2 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 ORY87416.1 - 8.5e-10 38.6 15.8 1.9e-05 24.8 0.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY87416.1 - 5.9e-09 36.0 14.3 0.0003 21.4 0.3 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY87416.1 - 5.7e-08 32.8 16.6 0.00029 21.1 0.3 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY87416.1 - 0.00012 21.9 0.5 0.00012 21.9 0.5 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 ORY87416.1 - 0.00059 20.1 1.1 0.5 10.8 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type C1_4 PF07975.12 ORY87416.1 - 0.011 16.0 2.5 0.27 11.5 0.7 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zf-C2H2_8 PF15909.5 ORY87416.1 - 0.013 15.8 5.4 0.029 14.7 3.5 1.9 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 ORY87416.1 - 0.028 15.1 6.1 1.3 9.7 0.1 2.4 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 ORY87416.1 - 0.039 14.3 7.8 1.3 9.4 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HTH_39 PF14090.6 ORY87416.1 - 0.057 13.2 0.0 0.57 10.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain zf-AN1 PF01428.16 ORY87416.1 - 1.2 9.3 9.9 35 4.7 0.1 3.4 2 1 1 3 3 3 0 AN1-like Zinc finger Zn-ribbon_8 PF09723.10 ORY87416.1 - 4 7.6 9.0 13 6.0 1.6 2.9 2 1 1 3 3 3 0 Zinc ribbon domain TSC22 PF01166.18 ORY87417.1 - 0.19 12.1 0.4 0.35 11.2 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family ADH_N PF08240.12 ORY87418.1 - 8.7e-23 80.3 0.8 1.8e-22 79.3 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY87418.1 - 4e-20 72.1 0.0 7.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY87418.1 - 6.2e-07 30.5 0.0 1.3e-06 29.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase An_peroxidase PF03098.15 ORY87419.1 - 3.4e-34 118.3 0.0 3.2e-20 72.2 0.0 3.8 1 1 2 3 3 3 3 Animal haem peroxidase MFS_1 PF07690.16 ORY87420.1 - 2.8e-31 108.7 35.3 1.1e-30 106.8 36.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MASE2 PF05230.11 ORY87420.1 - 0.28 11.3 5.1 0.22 11.6 0.5 2.8 2 1 0 2 2 2 0 MASE2 domain DUF3180 PF11377.8 ORY87420.1 - 0.33 11.1 0.0 0.33 11.1 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3180) UPF0016 PF01169.19 ORY87422.1 - 4.3e-45 151.9 18.9 1.6e-22 79.6 6.7 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 ORY87422.1 - 0.0012 18.7 7.3 0.0062 16.3 0.1 2.3 2 0 0 2 2 2 1 Putative manganese efflux pump LysE PF01810.18 ORY87422.1 - 0.038 13.4 10.3 0.092 12.2 2.2 2.6 2 1 0 2 2 2 0 LysE type translocator TerC PF03741.16 ORY87422.1 - 0.051 13.3 5.8 0.62 9.7 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein TerC family DUF4179 PF13786.6 ORY87422.1 - 0.21 12.1 2.2 3.8 8.1 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4179) DUF4131 PF13567.6 ORY87422.1 - 8.4 6.0 8.7 17 5.0 2.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) CCDC-167 PF15188.6 ORY87422.1 - 9.7 6.6 6.7 2.3 8.6 2.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 UNC-50 PF05216.13 ORY87423.1 - 2.4e-82 275.8 15.7 2.7e-82 275.6 15.7 1.0 1 0 0 1 1 1 1 UNC-50 family WW PF00397.26 ORY87424.1 - 4.9e-06 26.5 0.1 1e-05 25.5 0.1 1.6 1 0 0 1 1 1 1 WW domain RhoGEF PF00621.20 ORY87425.1 - 2e-32 112.9 0.0 1.1e-28 100.7 0.0 2.6 3 0 0 3 3 3 2 RhoGEF domain BAR PF03114.18 ORY87425.1 - 2.1e-05 24.3 0.0 4.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 BAR domain IL34 PF15036.6 ORY87425.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Interleukin 34 CDC45 PF02724.14 ORY87425.1 - 1.8 6.7 4.7 3.3 5.9 4.7 1.3 1 0 0 1 1 1 0 CDC45-like protein HAD_2 PF13419.6 ORY87426.1 - 3.7e-14 53.2 0.0 8.1e-14 52.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY87426.1 - 1.4e-11 45.1 0.0 1.6e-10 41.6 0.0 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY87426.1 - 4.4e-06 26.7 0.0 1.9e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ORY87426.1 - 0.021 14.9 0.0 0.64 10.2 0.0 2.5 2 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase His_Phos_2 PF00328.22 ORY87427.1 - 4.1e-19 69.2 0.0 6.3e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SRP19 PF01922.17 ORY87428.1 - 1.6e-29 102.7 0.0 2.8e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein Myb_Cef PF11831.8 ORY87429.1 - 6.2e-66 222.4 0.9 6.2e-66 222.4 0.9 3.9 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 ORY87429.1 - 9.3e-22 77.0 10.2 7.1e-11 42.1 1.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY87429.1 - 1.6e-19 69.9 7.4 1.3e-12 47.7 2.9 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY87429.1 - 0.4 10.8 3.1 1.8 8.7 0.1 3.3 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Thump_like PF18096.1 ORY87429.1 - 0.65 10.0 4.7 1.8 8.5 0.0 3.2 3 0 0 3 3 3 0 THUMP domain-like DUF3499 PF12005.8 ORY87429.1 - 9.4 6.9 11.7 0.16 12.5 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3499) zf-MYND PF01753.18 ORY87430.1 - 2e-10 40.6 9.8 3.6e-10 39.8 9.8 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY87430.1 - 0.018 15.3 6.1 0.037 14.3 6.1 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding UPF0203 PF05254.12 ORY87432.1 - 8.4e-21 74.0 0.2 1.1e-20 73.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) NDUF_B7 PF05676.13 ORY87432.1 - 0.059 13.1 0.7 4.1 7.2 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 ORY87432.1 - 0.077 13.0 1.1 4.7 7.3 0.1 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 ORY87432.1 - 0.082 13.1 2.3 7 6.9 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein SlyX PF04102.12 ORY87433.1 - 0.013 16.1 1.5 0.013 16.1 1.5 3.2 2 0 0 2 2 1 0 SlyX DUF572 PF04502.13 ORY87433.1 - 0.024 14.3 6.9 0.048 13.3 6.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) FAM60A PF15396.6 ORY87433.1 - 0.097 12.7 9.3 0.17 11.8 2.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A HSD3 PF15244.6 ORY87433.1 - 0.12 11.9 11.7 0.022 14.3 4.6 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 7, or HSD3 GCOM2 PF15328.6 ORY87433.1 - 0.41 11.0 14.1 2.4 8.5 2.3 2.1 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 EIIBC-GUT_N PF03612.14 ORY87433.1 - 1.2 8.8 7.4 5.5 6.7 2.6 2.3 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Ctr PF04145.15 ORY87433.1 - 1.4 9.5 6.2 11 6.6 0.4 2.3 2 0 0 2 2 2 0 Ctr copper transporter family FGF-BP1 PF06473.12 ORY87433.1 - 2.2 8.1 12.2 2.3 8.0 2.5 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Nop53 PF07767.11 ORY87433.1 - 3.3 7.0 20.3 1 8.7 10.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) SART-1 PF03343.13 ORY87433.1 - 3.6 6.0 14.9 0.81 8.2 5.1 2.1 2 0 0 2 2 2 0 SART-1 family Presenilin PF01080.17 ORY87433.1 - 3.6 6.2 15.6 0.99 8.1 4.4 2.1 2 0 0 2 2 2 0 Presenilin DUF966 PF06136.13 ORY87433.1 - 7 6.3 14.1 3.7 7.2 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.16 ORY87433.1 - 8.1 6.4 7.0 8.6 6.3 0.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDK2AP PF09806.9 ORY87433.1 - 9.5 6.2 22.7 0.94 9.5 10.4 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein tRNA_synthFbeta PF17759.1 ORY87434.1 - 2.5e-47 161.1 0.0 3.9e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 ORY87434.1 - 7.9e-25 87.5 0.1 1.3e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 ORY87434.1 - 2.8e-21 75.5 0.0 2.4e-18 66.1 0.0 2.5 2 0 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 ORY87434.1 - 1.7e-14 53.8 0.0 6.9e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain MipZ PF09140.11 ORY87434.1 - 0.0066 15.8 0.0 0.02 14.2 0.0 1.7 2 0 0 2 2 2 1 ATPase MipZ PIN_4 PF13638.6 ORY87435.1 - 5.9e-23 81.6 0.0 5.9e-23 81.6 0.0 2.2 2 0 0 2 2 2 1 PIN domain EST1_DNA_bind PF10373.9 ORY87435.1 - 2.5e-14 53.5 0.0 2.6e-13 50.1 0.0 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain PIN_9 PF18477.1 ORY87435.1 - 0.016 15.5 1.6 0.31 11.4 0.0 3.1 3 0 0 3 3 3 0 PIN like domain EST1 PF10374.9 ORY87435.1 - 0.017 15.7 0.0 1.9 9.1 0.0 3.4 3 0 0 3 3 3 0 Telomerase activating protein Est1 Med17 PF10156.9 ORY87435.1 - 0.11 11.2 2.9 0.26 9.9 2.5 1.7 2 0 0 2 2 2 0 Subunit 17 of Mediator complex DUF4632 PF15451.6 ORY87435.1 - 0.87 9.7 7.7 1.2 9.2 4.9 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4632) Sigma70_ner PF04546.13 ORY87435.1 - 2.3 8.1 8.7 1.3 8.9 5.9 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region Glycos_transf_2 PF00535.26 ORY87436.1 - 8.2e-24 84.3 0.1 2.6e-22 79.4 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_4 PF13439.6 ORY87436.1 - 5.4e-15 55.8 0.8 1.4e-14 54.5 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_tranf_2_2 PF10111.9 ORY87436.1 - 4.3e-12 46.1 0.0 2.1e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_4_4 PF13579.6 ORY87436.1 - 1.5e-11 45.0 1.7 2.4e-11 44.3 0.1 2.3 2 0 0 2 2 1 1 Glycosyl transferase 4-like domain Glyco_transf_8 PF01501.20 ORY87436.1 - 3e-09 36.8 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glyco_tranf_2_3 PF13641.6 ORY87436.1 - 9.5e-09 35.5 0.0 1.3e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY87436.1 - 7.8e-06 25.9 0.5 2.9e-05 24.1 0.2 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_trans_1_4 PF13692.6 ORY87436.1 - 0.00025 21.5 0.0 0.0013 19.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_7C PF02709.14 ORY87436.1 - 0.00027 20.5 0.0 0.00077 19.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glycos_transf_1 PF00534.20 ORY87436.1 - 0.00079 19.0 0.0 0.13 11.8 0.0 3.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ORY87436.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_tranf_2_4 PF13704.6 ORY87436.1 - 0.0062 17.0 0.4 0.027 15.0 0.4 2.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_64 PF09258.10 ORY87436.1 - 0.015 14.6 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Fringe PF02434.16 ORY87436.1 - 0.16 11.4 0.2 6.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Fringe-like Sod_Fe_C PF02777.18 ORY87437.1 - 1.7e-34 118.0 0.0 4.3e-34 116.8 0.0 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORY87437.1 - 3.7e-27 94.6 0.2 7.9e-27 93.6 0.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Arrestin_C PF02752.22 ORY87438.1 - 3.7e-05 24.2 0.0 0.0062 17.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY87438.1 - 0.012 15.6 0.0 0.14 12.3 0.0 2.5 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DIOX_N PF14226.6 ORY87439.1 - 1.8e-24 86.8 0.0 2.5e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY87439.1 - 2.2e-16 60.2 0.0 4.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Syntaphilin PF15290.6 ORY87440.1 - 0.0087 15.7 3.3 0.022 14.4 3.3 1.7 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp Alk_phosphatase PF00245.20 ORY87441.1 - 2.8e-89 299.9 0.0 4.4e-85 286.1 0.0 2.2 2 0 0 2 2 2 2 Alkaline phosphatase Bestrophin PF01062.21 ORY87442.1 - 3.8e-30 105.3 1.9 1.9e-19 70.2 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel p12I PF12233.8 ORY87442.1 - 0.93 10.0 5.9 0.99 9.9 2.1 2.8 2 1 1 3 3 3 0 Human adult T cell leukemia/lymphoma virus protein Mg_trans_NIPA PF05653.14 ORY87443.1 - 1.8e-95 319.4 25.8 2.4e-95 319.0 25.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY87443.1 - 3.5e-05 24.0 15.5 3.5e-05 24.0 15.5 3.3 2 1 0 2 2 2 1 EamA-like transporter family BAG PF02179.16 ORY87444.1 - 3.2e-12 46.7 0.0 4.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 ORY87444.1 - 6.4e-07 29.0 0.0 2.4e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY87444.1 - 0.0026 18.2 0.0 0.0092 16.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Ribosomal_L39 PF00832.20 ORY87445.1 - 6.5e-22 76.9 6.6 7.6e-22 76.7 6.6 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Nmad3 PF18754.1 ORY87445.1 - 0.024 14.2 0.4 0.024 14.2 0.4 1.0 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 Complex1_LYR_2 PF13233.6 ORY87447.1 - 4.6e-11 43.3 0.0 1.1e-10 42.1 0.0 1.6 1 1 0 1 1 1 1 Complex1_LYR-like ATP11 PF06644.11 ORY87448.1 - 1.2e-68 231.9 0.1 1.4e-68 231.7 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein AA_permease PF00324.21 ORY87449.1 - 2.5e-137 458.4 40.4 2.8e-137 458.2 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY87449.1 - 1.6e-39 135.9 47.4 2e-39 135.6 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_Gp23 PF10669.9 ORY87449.1 - 0.01 16.2 0.1 0.01 16.2 0.1 1.8 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RabGAP-TBC PF00566.18 ORY87450.1 - 5.2e-44 150.5 0.0 7e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MFS_1 PF07690.16 ORY87451.1 - 4.5e-37 127.8 33.6 6.1e-37 127.4 33.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD-oxidase_C PF02913.19 ORY87452.1 - 1.2e-54 185.6 0.0 2.1e-54 184.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY87452.1 - 2e-23 82.7 2.1 7e-17 61.5 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain SF1-HH PF16275.5 ORY87453.1 - 3.7e-36 123.9 0.0 7.6e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 ORY87453.1 - 5.1e-11 42.1 11.0 1.5e-05 24.9 0.8 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 ORY87453.1 - 1.2e-06 28.2 0.1 2.1e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 ORY87453.1 - 7.9e-06 25.7 6.2 0.0025 17.7 1.8 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 ORY87453.1 - 0.0099 15.7 11.0 0.058 13.2 0.9 2.9 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 ORY87453.1 - 0.014 15.1 6.9 0.52 10.1 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 ORY87453.1 - 0.48 10.8 6.0 1 9.8 6.0 1.5 1 0 0 1 1 1 0 DnaJ central domain Glyco_transf_25 PF01755.17 ORY87454.1 - 6.3e-08 32.7 0.0 0.0042 17.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) AAA_33 PF13671.6 ORY87454.1 - 0.03 14.5 0.4 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain Bestrophin PF01062.21 ORY87455.1 - 4.4e-21 75.6 3.3 4.7e-13 49.2 0.2 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel OAR PF03826.17 ORY87457.1 - 0.021 14.6 0.8 0.041 13.7 0.8 1.4 1 0 0 1 1 1 0 OAR domain Hemerythrin PF01814.23 ORY87458.1 - 1.8e-10 41.6 2.2 2.7e-10 41.0 2.1 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Diphthamide_syn PF01866.17 ORY87459.1 - 8.4e-98 327.5 0.0 2.2e-97 326.1 0.0 1.6 1 1 0 1 1 1 1 Putative diphthamide synthesis protein GST_C_3 PF14497.6 ORY87460.1 - 4e-15 55.8 0.3 6.1e-15 55.2 0.3 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY87460.1 - 1.4e-08 34.8 0.0 2.5e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY87460.1 - 7.3e-07 29.4 0.0 2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY87460.1 - 0.00023 21.1 0.0 0.00071 19.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phosducin PF02114.16 ORY87461.1 - 3.1e-18 65.7 0.1 3.2e-15 55.8 0.0 3.2 1 1 1 2 2 2 2 Phosducin LRR_6 PF13516.6 ORY87461.1 - 6.8e-14 50.7 23.1 0.016 15.2 0.1 9.6 10 0 0 10 10 10 6 Leucine Rich repeat HTH_16 PF12645.7 ORY87461.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain LRR_8 PF13855.6 ORY87461.1 - 0.081 12.7 6.7 11 5.9 1.3 5.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 ORY87461.1 - 0.74 10.6 9.6 1.2e+02 3.9 0.0 7.1 9 0 0 9 9 9 0 Leucine Rich Repeat KH_1 PF00013.29 ORY87462.1 - 3.7e-38 129.2 3.4 2.2e-08 33.8 0.0 6.9 7 0 0 7 7 7 6 KH domain HTH_21 PF13276.6 ORY87462.1 - 0.16 12.1 0.0 25 5.1 0.0 2.4 2 0 0 2 2 2 0 HTH-like domain MFS_1 PF07690.16 ORY87463.1 - 2.1e-27 96.0 31.8 2.1e-27 96.0 31.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily CD225 PF04505.12 ORY87463.1 - 0.087 13.0 6.6 0.73 10.0 0.2 3.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Dus PF01207.17 ORY87464.1 - 3.5e-51 174.1 0.0 5.7e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 ORY87464.1 - 5.7e-06 26.0 11.4 0.00086 19.1 0.6 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 ORY87464.1 - 0.00026 20.8 11.2 0.0044 16.9 0.1 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY87464.1 - 0.014 15.4 13.7 0.22 11.6 1.2 2.5 2 0 0 2 2 2 0 Zinc finger domain Torus PF16131.5 ORY87464.1 - 0.43 11.3 6.1 2.6 8.8 1.8 2.8 2 1 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 ORY87464.1 - 3.1 8.4 7.7 6.7 7.4 0.1 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DSBA PF01323.20 ORY87465.1 - 2.4e-59 200.4 0.0 3.3e-28 98.8 0.0 2.8 2 1 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY87465.1 - 0.031 14.4 0.0 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin Ribosomal_S9 PF00380.19 ORY87466.1 - 8.2e-41 139.3 0.3 1.3e-40 138.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3231 PF11553.8 ORY87466.1 - 0.22 11.1 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) CPSase_L_D2 PF02786.17 ORY87467.1 - 2.6e-77 259.1 0.2 4.7e-77 258.3 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ORY87467.1 - 4.6e-71 238.7 0.0 7.7e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ORY87467.1 - 4.9e-39 133.3 0.1 1e-38 132.2 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY87467.1 - 6.9e-31 106.5 0.0 1.7e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ORY87467.1 - 1.6e-25 90.2 0.1 3.2e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ORY87467.1 - 3.4e-16 58.8 4.3 1e-15 57.3 4.3 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ORY87467.1 - 1.1e-11 44.4 2.5 8.1e-05 22.4 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ORY87467.1 - 8.6e-09 35.2 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY87467.1 - 8.8e-07 28.6 0.1 2.7e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY87467.1 - 6.2e-06 26.3 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ORY87467.1 - 4e-05 23.3 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 ORY87467.1 - 0.00068 18.9 1.2 0.062 12.5 0.1 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion AP_endonuc_2 PF01261.24 ORY87467.1 - 0.0012 18.3 0.0 0.0039 16.6 0.0 1.8 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ATP-grasp_4 PF13535.6 ORY87467.1 - 0.0017 18.0 0.0 0.0047 16.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 ORY87467.1 - 0.0034 18.0 4.2 0.28 11.9 0.6 3.1 3 0 0 3 3 2 1 HlyD family secretion protein GARS_A PF01071.19 ORY87467.1 - 0.017 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 ORY87467.1 - 0.069 12.9 0.1 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 ORY87467.1 - 0.11 11.7 0.0 0.3 10.3 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 ORY87467.1 - 0.21 11.6 1.6 0.64 10.0 1.6 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Helicase_C PF00271.31 ORY87468.1 - 3.3e-20 72.5 0.6 3.2e-16 59.7 0.1 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 ORY87468.1 - 3.4e-18 66.0 0.1 7.1e-17 61.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 ORY87468.1 - 2.2e-10 41.1 0.7 2.2e-10 41.1 0.7 2.6 3 0 0 3 3 3 1 RecQ zinc-binding ResIII PF04851.15 ORY87468.1 - 4.5e-05 23.5 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pox_Ag35 PF03286.14 ORY87468.1 - 0.0046 16.8 15.8 0.06 13.1 3.7 2.5 2 0 0 2 2 2 2 Pox virus Ag35 surface protein MerR-DNA-bind PF09278.11 ORY87468.1 - 0.14 12.7 3.3 0.48 11.0 3.3 2.0 1 0 0 1 1 1 0 MerR, DNA binding Spc7 PF08317.11 ORY87468.1 - 0.17 10.7 6.1 0.34 9.8 6.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 ORY87468.1 - 0.23 12.1 2.7 17 6.1 0.5 2.8 2 0 0 2 2 2 0 SlyX BUD22 PF09073.10 ORY87468.1 - 7 5.9 26.0 6 6.1 9.2 2.4 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 ORY87468.1 - 7.6 6.2 24.1 0.2 11.4 5.3 2.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein CRC_subunit PF08624.10 ORY87470.1 - 4.5e-44 150.2 0.0 6.1e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 ORY87473.1 - 1.1e-26 92.8 0.2 1.5e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY87473.1 - 4.7e-06 27.0 0.0 5.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY87473.1 - 0.0028 17.7 0.0 0.0038 17.3 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold zf-Tim10_DDP PF02953.15 ORY87473.1 - 0.043 13.5 1.4 0.075 12.7 1.4 1.4 1 0 0 1 1 1 0 Tim10/DDP family zinc finger PAN_3 PF08277.12 ORY87473.1 - 0.087 12.6 0.8 0.18 11.7 0.8 1.5 1 0 0 1 1 1 0 PAN-like domain Bromo_TP PF07524.13 ORY87473.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-X PF09415.10 ORY87473.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TFIID-18kDa PF02269.16 ORY87473.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.13 ORY87473.1 - 0.16 12.5 0.0 0.93 10.0 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Glyco_transf_92 PF01697.27 ORY87474.1 - 1.3e-09 38.1 0.0 4.2e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 ORY87474.1 - 5.7e-09 36.4 0.3 0.0011 19.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 WD40 PF00400.32 ORY87476.1 - 6.1e-09 36.4 0.3 0.004 18.0 0.0 5.7 6 0 0 6 6 6 1 WD domain, G-beta repeat LisH PF08513.11 ORY87476.1 - 0.00039 20.3 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 LisH ANAPC4_WD40 PF12894.7 ORY87476.1 - 0.0025 18.1 0.0 5.5 7.4 0.1 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY87476.1 - 0.0099 15.8 0.8 0.2 11.6 0.0 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORY87476.1 - 0.09 11.7 0.0 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY87476.1 - 0.1 11.1 0.4 0.19 10.2 0.1 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain BCS1_N PF08740.11 ORY87477.1 - 5.2e-51 173.3 1.1 7.2e-51 172.8 1.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORY87477.1 - 3.6e-20 72.7 0.0 9.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY87477.1 - 9.8e-05 22.8 0.1 0.00053 20.4 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ORY87477.1 - 0.00076 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 ORY87477.1 - 0.0035 17.5 0.1 0.013 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY87477.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 ORY87477.1 - 0.012 15.6 0.0 0.06 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY87477.1 - 0.014 14.9 0.0 0.054 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY87477.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 ORY87477.1 - 0.041 14.4 0.0 0.08 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY87477.1 - 0.046 14.0 0.0 0.21 11.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY87477.1 - 0.06 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 ORY87477.1 - 0.077 13.5 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 ORY87477.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORY87477.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 ORY87477.1 - 0.12 11.7 0.0 0.33 10.3 0.0 1.7 1 1 1 2 2 2 0 KaiC PPV_E1_C PF00519.17 ORY87477.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RabGAP-TBC PF00566.18 ORY87478.1 - 2.5e-23 82.9 0.0 8.5e-23 81.1 0.0 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain zf-MYND PF01753.18 ORY87479.1 - 1.2e-10 41.3 12.4 2e-10 40.6 12.4 1.4 1 0 0 1 1 1 1 MYND finger Xol-1_N PF09108.10 ORY87479.1 - 0.04 13.8 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal zf-FLZ PF04570.14 ORY87479.1 - 0.064 12.7 6.6 0.14 11.7 6.6 1.5 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 zf-Mss51 PF13824.6 ORY87479.1 - 0.91 9.7 5.6 1.7 8.8 5.6 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 ORY87479.1 - 5.9 7.3 11.9 11 6.4 11.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding NAP PF00956.18 ORY87482.1 - 1.9e-89 299.4 11.0 1.9e-89 299.4 11.0 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) eIF-3c_N PF05470.12 ORY87482.1 - 6.9e-05 21.4 0.0 0.12 10.6 0.0 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus LIN37 PF15306.6 ORY87482.1 - 0.011 15.9 0.1 0.011 15.9 0.1 2.4 3 1 0 3 3 3 0 LIN37 RNA_pol_3_Rpc31 PF11705.8 ORY87482.1 - 1.9 8.7 29.1 2.9 8.1 13.6 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 ORY87482.1 - 8.7 6.0 26.0 1.5 8.5 10.8 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-MYND PF01753.18 ORY87483.1 - 0.0012 18.9 1.7 0.0024 17.9 1.7 1.5 1 0 0 1 1 1 1 MYND finger Complex1_LYR_2 PF13233.6 ORY87483.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Homeodomain PF00046.29 ORY87484.1 - 1.5e-20 72.8 2.3 1.6e-20 72.7 2.3 1.0 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 ORY87484.1 - 0.0083 15.6 0.0 0.0085 15.5 0.0 1.1 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 ORY87484.1 - 0.013 15.4 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Homeobox KN domain HTH_Mga PF08280.11 ORY87484.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 1 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain ARPC4 PF05856.12 ORY87485.1 - 1.2e-75 252.7 4.6 1.3e-75 252.6 4.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RNA_pol_Rpb4 PF03874.16 ORY87486.1 - 1.3e-19 70.8 3.9 1.7e-19 70.4 3.9 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.21 ORY87486.1 - 0.046 14.0 0.5 0.25 11.6 0.3 2.2 2 0 0 2 2 2 0 Death effector domain DUF2913 PF11140.8 ORY87486.1 - 0.071 12.8 0.2 0.16 11.7 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2913) Mis12 PF05859.12 ORY87487.1 - 1.6e-26 93.0 0.8 2.7e-26 92.2 0.8 1.4 1 0 0 1 1 1 1 Mis12 protein MAD PF05557.13 ORY87488.1 - 2e-52 178.5 62.7 2.3e-52 178.3 62.7 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein NumbF PF06311.12 ORY87488.1 - 0.024 15.2 2.2 0.2 12.2 0.4 3.3 3 1 0 3 3 3 0 NUMB domain DUF1664 PF07889.12 ORY87488.1 - 0.038 14.0 0.7 0.038 14.0 0.7 6.9 6 1 1 7 7 7 0 Protein of unknown function (DUF1664) Dfp1_Him1_M PF08630.10 ORY87489.1 - 9e-34 116.4 0.0 2e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 ORY87489.1 - 6.4e-21 74.2 0.8 1e-20 73.6 0.2 1.7 2 0 0 2 2 2 1 DBF zinc finger BRCT PF00533.26 ORY87489.1 - 0.00024 21.4 0.0 0.00051 20.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY87489.1 - 0.0062 16.5 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain UPF0524 PF15823.5 ORY87489.1 - 0.0097 15.3 1.1 0.0097 15.3 1.1 1.8 2 0 0 2 2 2 1 UPF0524 of C3orf70 FAD_binding_4 PF01565.23 ORY87490.1 - 5.1e-22 78.1 1.6 1.1e-21 77.0 1.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY87490.1 - 7.1e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like ELP6 PF09807.9 ORY87491.1 - 9.1e-23 81.0 0.1 2.9e-12 46.5 0.0 2.0 1 1 1 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 ORY87491.1 - 1.1e-10 41.5 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Elongator subunit Iki1 AAA_25 PF13481.6 ORY87491.1 - 0.00051 19.7 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 ORY87491.1 - 0.011 14.9 0.1 0.028 13.6 0.0 1.4 1 1 0 2 2 2 0 PAXNEB protein ATPase PF06745.13 ORY87491.1 - 0.031 13.6 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 KaiC DUF835 PF05763.12 ORY87491.1 - 0.046 13.4 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF835) Ribosomal_S17e PF00833.18 ORY87493.1 - 6.1e-62 207.0 0.0 7.9e-62 206.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.19 ORY87494.1 - 1.4e-23 83.3 0.1 1.9e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 adh_short_C2 PF13561.6 ORY87495.1 - 5.1e-46 157.1 2.7 6.4e-46 156.8 2.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY87495.1 - 3.2e-34 118.1 1.9 4.1e-34 117.8 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY87495.1 - 5.4e-11 42.7 0.4 7.8e-11 42.2 0.4 1.1 1 0 0 1 1 1 1 KR domain Tubulin_C PF03953.17 ORY87495.1 - 0.011 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin C-terminal domain Tmemb_9 PF05434.11 ORY87496.1 - 0.15 12.0 0.1 0.2 11.5 0.1 1.1 1 0 0 1 1 1 0 TMEM9 Aminotran_1_2 PF00155.21 ORY87497.1 - 1.1e-59 202.5 0.0 1.3e-59 202.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 ORY87498.1 - 1.3e-38 130.3 21.3 1.9e-07 31.6 1.7 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY87498.1 - 4.4e-15 55.8 0.1 0.021 15.1 0.0 6.5 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY87498.1 - 0.00041 19.4 0.2 0.81 8.6 0.0 4.2 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 ORY87498.1 - 0.26 9.3 0.0 0.51 8.3 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Pkinase PF00069.25 ORY87499.1 - 1.2e-61 208.4 0.0 1.4e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY87499.1 - 5.1e-31 107.9 0.0 6.3e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY87499.1 - 2e-05 24.0 0.0 0.0001 21.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY87499.1 - 0.038 13.9 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY87499.1 - 0.25 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4259 PF14078.6 ORY87500.1 - 0.015 16.1 0.2 0.019 15.7 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) PAP2 PF01569.21 ORY87501.1 - 3.3e-20 72.3 4.3 1.3e-19 70.3 4.3 2.0 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ORY87501.1 - 0.0012 18.6 8.0 0.0032 17.2 8.0 1.9 1 1 0 1 1 1 1 PAP2 superfamily PrgI PF12666.7 ORY87501.1 - 3.4 8.4 9.2 1.4 9.7 1.4 3.4 3 1 0 3 3 3 0 PrgI family protein AAA PF00004.29 ORY87502.1 - 6.8e-43 146.3 0.0 1.3e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY87502.1 - 2.9e-12 46.2 0.1 6.2e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORY87502.1 - 2.3e-07 31.1 0.0 4.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 ORY87502.1 - 3e-07 30.3 0.3 6.7e-07 29.2 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORY87502.1 - 8.5e-06 25.8 0.0 3.3e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY87502.1 - 8.9e-06 26.2 0.1 8.6e-05 23.0 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY87502.1 - 1.2e-05 25.6 0.1 0.0051 17.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY87502.1 - 9.5e-05 22.2 0.0 0.00022 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORY87502.1 - 0.00027 21.5 0.1 0.021 15.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 ORY87502.1 - 0.0011 18.3 0.0 0.0022 17.2 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ORY87502.1 - 0.0014 18.8 0.0 0.0032 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY87502.1 - 0.0021 17.8 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 ORY87502.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY87502.1 - 0.0073 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.16 ORY87502.1 - 0.0081 15.6 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 ORY87502.1 - 0.0095 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY87502.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 ORY87502.1 - 0.015 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORY87502.1 - 0.015 15.0 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY87502.1 - 0.025 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY87502.1 - 0.026 14.2 0.1 0.1 12.3 0.0 2.0 3 0 0 3 3 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 ORY87502.1 - 0.035 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY87502.1 - 0.046 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 ORY87502.1 - 0.055 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 ORY87502.1 - 0.055 13.0 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY87502.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 ORY87502.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein RILP PF11461.8 ORY87502.1 - 0.07 13.4 1.0 0.14 12.4 1.0 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein NACHT PF05729.12 ORY87502.1 - 0.071 13.0 0.0 0.68 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 ORY87502.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 ORY87502.1 - 0.1 12.3 0.1 0.65 9.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF5406 PF17400.2 ORY87502.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5406) AAA_19 PF13245.6 ORY87502.1 - 0.13 12.6 0.1 0.47 10.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 ORY87502.1 - 0.15 11.8 0.1 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain 4HBT_3 PF13622.6 ORY87503.1 - 6.2e-26 92.2 0.3 8.3e-26 91.7 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ORY87503.1 - 0.0073 16.6 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Peptidase_M14 PF00246.24 ORY87504.1 - 6.9e-66 223.0 0.0 8.8e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Ribosomal_S8e PF01201.22 ORY87507.1 - 7.5e-46 155.7 2.3 1.1e-45 155.2 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Cmc1 PF08583.10 ORY87508.1 - 0.006 16.6 0.4 0.0071 16.3 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 ORY87508.1 - 0.014 15.6 0.3 0.039 14.1 0.3 1.7 1 1 0 1 1 1 0 CHCH domain Nexin_C PF08628.12 ORY87508.1 - 0.14 12.8 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 Sorting nexin C terminal ANAPC5 PF12862.7 ORY87509.1 - 1e-09 38.3 0.2 3.5e-09 36.6 0.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 ORY87509.1 - 0.028 14.7 7.9 0.044 14.1 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY87509.1 - 5.5 7.3 5.9 36 4.8 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1279 PF06916.13 ORY87510.1 - 2.2e-17 63.4 0.0 4.6e-17 62.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) KfrA_N PF11740.8 ORY87510.1 - 0.1 13.3 1.4 0.18 12.5 1.4 1.4 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Sybindin PF04099.12 ORY87511.1 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family NAD_binding_1 PF00175.21 ORY87512.1 - 1.9e-31 109.0 0.0 2.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY87512.1 - 2.1e-30 105.0 0.0 3.6e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY87512.1 - 0.00011 22.3 0.0 0.00042 20.5 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pkinase PF00069.25 ORY87513.1 - 3e-61 207.1 0.0 3.9e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY87513.1 - 1.1e-35 123.2 0.0 1.7e-35 122.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY87513.1 - 0.0021 18.0 0.1 0.017 15.1 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY87513.1 - 0.0023 17.3 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY87513.1 - 0.0062 15.4 0.0 0.012 14.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY87513.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain HLH PF00010.26 ORY87515.1 - 8.9e-14 51.2 0.0 2.3e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain G_glu_transpept PF01019.21 ORY87516.1 - 1.6e-153 512.2 0.0 1.9e-153 512.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase SNARE PF05739.19 ORY87516.1 - 0.13 12.3 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 SNARE domain DUF3431 PF11913.8 ORY87517.1 - 3.6e-06 26.9 0.0 7e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) ChAPs PF09295.10 ORY87518.1 - 3e-140 467.7 1.0 4e-94 315.8 0.0 3.0 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 ORY87518.1 - 1.9e-05 24.4 6.0 0.044 13.9 0.4 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY87518.1 - 0.00033 21.1 1.8 0.44 11.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY87518.1 - 0.0066 17.0 5.2 0.11 13.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY87518.1 - 0.018 14.8 1.8 3.8 7.5 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY87518.1 - 0.045 14.6 16.2 8.9 7.4 0.0 6.5 5 1 2 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY87518.1 - 0.061 13.6 1.3 1.1 9.6 0.2 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 ORY87518.1 - 0.27 10.4 8.1 5.8 6.0 0.2 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY87518.1 - 1.6 9.2 7.9 4.8 7.6 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY87518.1 - 2 9.2 18.9 0.35 11.6 5.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat An_peroxidase PF03098.15 ORY87519.1 - 9e-34 116.9 0.0 1.3e-22 80.1 0.0 3.9 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 ORY87519.1 - 2.8e-12 46.2 0.1 1.9e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 Cytochrome P450 DUF5434 PF17502.2 ORY87519.1 - 0.084 12.9 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5434) CARDB PF07705.11 ORY87519.1 - 0.097 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 CARDB CI-B14_5a PF07347.12 ORY87520.1 - 0.0082 16.0 0.3 0.013 15.3 0.3 1.6 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) VWA_N2 PF16164.5 ORY87520.1 - 0.06 13.5 0.5 0.14 12.3 0.2 1.7 2 0 0 2 2 2 0 VWA N-terminal MR_MLE_C PF13378.6 ORY87521.1 - 7.4e-41 140.1 0.0 9.8e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ORY87521.1 - 2e-10 40.9 0.0 3.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Metallophos_2 PF12850.7 ORY87522.1 - 3.3e-11 43.7 0.0 5.5e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 ORY87522.1 - 0.043 14.3 0.0 9.2 6.7 0.0 2.2 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Tim54 PF11711.8 ORY87522.1 - 0.49 9.1 1.8 0.49 9.1 0.7 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AA_kinase PF00696.28 ORY87523.1 - 8.6e-35 120.5 0.0 4.5e-34 118.1 0.0 1.9 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 ORY87523.1 - 4.6e-11 42.3 3.5 1.7e-06 27.7 0.1 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 ORY87523.1 - 1.2e-08 34.6 1.9 9.2e-07 28.6 0.2 2.5 2 0 0 2 2 2 2 ACT domain ERO1 PF04137.15 ORY87524.1 - 2.6e-129 431.4 0.0 4.3e-129 430.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) tRNA-synt_2c PF01411.19 ORY87525.1 - 3.1e-207 689.5 0.0 3.9e-207 689.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORY87525.1 - 4.8e-17 61.8 0.1 1e-16 60.8 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ORY87525.1 - 1.9e-10 41.3 5.8 3.8e-10 40.3 5.8 1.5 1 0 0 1 1 1 1 DHHA1 domain THOC7 PF05615.13 ORY87526.1 - 1.2e-15 58.0 14.2 1.7e-15 57.5 5.8 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 Rota_NSP3 PF01665.16 ORY87526.1 - 0.025 13.7 1.5 0.045 12.9 1.5 1.4 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 FapA PF03961.13 ORY87526.1 - 0.16 10.6 4.9 0.21 10.2 4.9 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 ORY87526.1 - 0.23 11.5 4.8 7.2 6.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YtxH PF12732.7 ORY87526.1 - 0.25 11.9 7.7 0.066 13.8 3.0 2.3 2 1 0 2 2 2 0 YtxH-like protein DUF445 PF04286.12 ORY87526.1 - 0.31 10.8 7.5 0.39 10.5 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) WXG100 PF06013.12 ORY87526.1 - 0.45 10.8 5.3 0.59 10.4 0.2 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Seryl_tRNA_N PF02403.22 ORY87526.1 - 0.54 10.5 10.2 0.13 12.5 5.8 2.2 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain RNAse_A_bac PF18431.1 ORY87526.1 - 0.68 10.9 3.5 1.1 10.2 1.2 2.0 1 1 1 2 2 2 0 Bacterial CdiA-CT RNAse A domain Med21 PF11221.8 ORY87526.1 - 1.2 9.4 9.6 0.91 9.8 7.3 2.3 1 1 1 2 2 2 0 Subunit 21 of Mediator complex JTB PF05439.12 ORY87527.1 - 0.00057 19.9 0.4 0.00057 19.9 0.4 2.0 2 0 0 2 2 2 1 Jumping translocation breakpoint protein (JTB) Rrn6 PF10214.9 ORY87527.1 - 0.00093 17.8 0.7 0.0012 17.5 0.7 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF3915 PF13054.6 ORY87527.1 - 0.22 11.5 1.6 0.37 10.8 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Fer2_3 PF13085.6 ORY87528.1 - 2.2e-34 117.8 0.1 3.3e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ORY87528.1 - 3e-09 37.3 5.1 3e-09 37.3 5.1 2.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY87528.1 - 2.7e-07 30.6 4.0 2.7e-07 30.6 4.0 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORY87528.1 - 6.8e-07 29.6 7.3 6.8e-07 29.6 7.3 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 ORY87528.1 - 0.0039 17.1 2.8 0.0094 15.9 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 ORY87528.1 - 0.2 11.9 12.5 0.035 14.3 6.7 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 ORY87528.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 ORY87528.1 - 1 10.0 15.3 0.1 13.2 7.9 2.8 2 2 1 3 3 3 0 4Fe-4S dicluster domain Pro_isomerase PF00160.21 ORY87529.1 - 1.3e-14 54.8 0.0 1.4e-14 54.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD KilA-N PF04383.13 ORY88011.1 - 0.00039 20.2 0.3 0.0012 18.7 0.3 1.7 1 1 0 1 1 1 1 KilA-N domain DUF2781 PF10914.8 ORY88012.1 - 2.5e-36 125.3 9.5 2.8e-36 125.1 9.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DPBB_1 PF03330.18 ORY88013.1 - 0.00039 20.6 0.4 0.005 17.1 0.4 2.9 1 1 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 ORY88013.1 - 0.067 13.2 0.1 0.2 11.7 0.1 1.8 1 1 0 1 1 1 0 Pollen allergen DPBB_1 PF03330.18 ORY88014.1 - 8.2e-10 38.8 0.5 3.3e-09 36.9 0.5 2.1 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY88014.1 - 0.00032 20.5 0.2 0.00061 19.6 0.2 1.5 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 ORY88014.1 - 0.0024 18.0 1.2 0.049 13.7 0.2 2.2 1 1 0 2 2 2 1 Cerato-platanin Pollen_allerg_1 PF01357.21 ORY88014.1 - 0.09 12.8 0.2 0.2 11.7 0.2 1.6 1 0 0 1 1 1 0 Pollen allergen HATPase_c PF02518.26 ORY88015.1 - 1.1e-20 74.1 0.0 4.2e-20 72.3 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY88015.1 - 1.2e-18 67.2 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY88015.1 - 6.9e-07 29.2 0.4 2.3e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF485 PF04341.12 ORY88015.1 - 0.1 12.6 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF2456 PF10445.9 ORY88015.1 - 1.5 8.9 6.0 0.43 10.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DUF2834 PF11196.8 ORY88016.1 - 3.1e-17 62.7 15.7 6.5e-11 42.4 0.9 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) SNF2_N PF00176.23 ORY88017.1 - 6.6e-51 173.1 0.0 2e-50 171.5 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY88017.1 - 3.8e-14 53.0 0.0 1.1e-13 51.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY88017.1 - 1.1e-09 38.5 0.8 5.3e-09 36.3 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY88017.1 - 6.4e-06 25.6 0.1 0.00023 20.4 0.0 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 ORY88017.1 - 0.056 13.7 0.5 0.95 9.7 0.0 2.9 3 1 0 3 3 3 0 AAA domain SNF2_N PF00176.23 ORY88018.1 - 7e-55 186.1 0.0 1.9e-54 184.7 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY88018.1 - 2.7e-13 50.2 0.0 2.2e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY88018.1 - 2.6e-07 30.8 0.1 7.4e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY88018.1 - 0.00058 20.1 0.1 0.003 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain HDA2-3 PF11496.8 ORY88018.1 - 0.0059 15.8 0.0 0.14 11.3 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SHD1 PF03983.12 ORY88019.1 - 9e-31 105.5 0.0 1.7e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 ORY88019.1 - 2.2e-29 101.1 4.6 3.7e-10 39.5 0.1 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.28 ORY88019.1 - 6e-23 80.2 8.4 5.7e-07 29.1 0.0 4.8 4 1 0 4 4 4 3 SH3 domain SH3_2 PF07653.17 ORY88019.1 - 3.4e-16 58.7 0.0 0.0013 18.4 0.0 4.7 5 0 0 5 5 5 4 Variant SH3 domain DUF1720 PF08226.11 ORY88019.1 - 0.0073 16.7 168.9 0.054 13.9 37.4 7.7 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) DUF5521 PF17659.1 ORY88019.1 - 2.5 5.8 3.3 3.5 5.3 3.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) DASH_Spc19 PF08287.11 ORY88020.1 - 1.1e-26 93.6 4.7 2.6e-25 89.2 3.9 2.0 1 1 1 2 2 2 2 Spc19 Baculo_PEP_C PF04513.12 ORY88020.1 - 0.063 13.3 0.1 0.53 10.3 0.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 ORY88020.1 - 0.17 10.8 1.1 0.25 10.2 1.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SLIDE PF09111.10 ORY88020.1 - 0.27 11.3 1.7 8.2 6.5 0.1 2.2 1 1 1 2 2 2 0 SLIDE ERCC4 PF02732.15 ORY88022.1 - 1.9e-20 73.7 0.1 3.7e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 ORY88022.1 - 0.004 17.5 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain Rad9 PF04139.13 ORY88023.1 - 1.9e-53 181.5 0.0 2.4e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 AflR PF08493.10 ORY88023.1 - 1.1 8.7 5.2 1.9 7.9 5.2 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF1640 PF07798.11 ORY88024.1 - 5.8e-55 186.0 4.7 6.6e-55 185.8 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HALZ PF02183.18 ORY88024.1 - 0.0043 17.2 0.2 0.031 14.5 0.7 2.2 2 1 0 2 2 2 1 Homeobox associated leucine zipper Fungal_TACC PF12709.7 ORY88024.1 - 0.016 15.6 0.9 0.039 14.4 0.9 1.6 1 0 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins COG5 PF10392.9 ORY88024.1 - 0.076 13.2 3.7 0.14 12.3 1.4 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 LIF_OSM PF01291.17 ORY88024.1 - 0.11 12.7 0.3 0.2 11.8 0.2 1.6 1 1 0 1 1 1 0 LIF / OSM family DEAD PF00270.29 ORY88025.1 - 2.2e-45 154.6 0.2 4e-45 153.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY88025.1 - 2.7e-20 72.7 0.0 2.6e-18 66.4 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY88025.1 - 8e-09 35.7 0.0 1.3e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY88025.1 - 0.062 12.5 0.0 0.099 11.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Helicase_RecD PF05127.14 ORY88025.1 - 0.12 12.3 0.1 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Helicase MFS_1 PF07690.16 ORY88026.1 - 6.6e-29 100.9 34.1 9.8e-29 100.4 34.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RPAP2_Rtr1 PF04181.13 ORY88028.1 - 1.7e-14 53.8 0.2 3.3e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family CybS PF05328.12 ORY88029.1 - 5.3e-43 145.9 0.1 5.7e-43 145.8 0.1 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit VMA21 PF09446.10 ORY88030.1 - 5.9e-13 48.7 4.6 8.7e-13 48.2 4.6 1.3 1 0 0 1 1 1 1 VMA21-like domain UbiD PF01977.16 ORY88031.1 - 5.7e-121 404.2 0.0 7.5e-121 403.8 0.0 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.19 ORY88032.1 - 9e-20 71.0 0.1 1.2e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein PITH PF06201.13 ORY88033.1 - 3.5e-28 98.7 0.0 5.8e-28 98.0 0.0 1.3 1 1 0 1 1 1 1 PITH domain Glyco_hydro_18 PF00704.28 ORY88034.1 - 6.5e-84 282.3 0.6 7.4e-84 282.1 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.18 ORY88035.1 - 3.4e-07 29.6 0.1 5.3e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY88035.1 - 7.9e-07 29.1 8.8 1.3e-06 28.4 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAT2_N PF07001.11 ORY88035.1 - 0.16 12.4 4.6 0.37 11.2 0.2 2.6 2 0 0 2 2 2 0 BAT2 N-terminus UCH PF00443.29 ORY88036.1 - 7.7e-66 222.2 0.0 1e-65 221.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY88036.1 - 1.9e-18 67.2 0.0 9.4e-18 64.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 ORY88036.1 - 8.7e-05 23.0 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Filo_glycop PF01611.16 ORY88037.1 - 0.049 12.6 1.1 0.063 12.2 1.1 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein zf-MYND PF01753.18 ORY88038.1 - 9.8e-05 22.4 11.3 0.00026 21.0 11.3 1.8 1 0 0 1 1 1 1 MYND finger ADH_zinc_N PF00107.26 ORY88039.1 - 2.8e-25 88.8 0.7 4.3e-25 88.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY88039.1 - 4.5e-17 63.4 0.0 8.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY88039.1 - 2e-13 50.2 0.1 4.6e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 ORY88039.1 - 3.2e-05 23.5 0.1 4.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 ORY88039.1 - 0.0055 16.1 0.0 0.0099 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 ORY88039.1 - 0.008 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 ORY88040.1 - 7.5e-26 91.1 0.0 9.1e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY88040.1 - 5.5e-07 29.4 0.0 8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY88040.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORY88040.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family IBR PF01485.21 ORY88042.1 - 1.5e-16 60.4 50.4 1.3e-09 38.1 9.7 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORY88042.1 - 4.5e-06 26.4 6.0 4.5e-06 26.4 6.0 4.7 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY88042.1 - 1e-05 25.2 3.6 1e-05 25.2 3.6 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY88042.1 - 7.7e-05 22.9 3.4 7.7e-05 22.9 3.4 4.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY88042.1 - 0.00018 21.4 1.9 0.00018 21.4 1.9 3.9 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY88042.1 - 0.016 15.2 6.2 0.016 15.2 6.2 3.9 3 1 0 3 3 3 0 zinc-RING finger domain DUF4795 PF16043.5 ORY88042.1 - 0.28 10.8 6.5 0.036 13.7 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) LSM PF01423.22 ORY88043.1 - 2.8e-18 65.4 0.8 3.5e-18 65.0 0.8 1.1 1 0 0 1 1 1 1 LSM domain LRR_6 PF13516.6 ORY88043.1 - 0.062 13.4 0.8 15 6.0 0.0 3.2 3 1 1 4 4 4 0 Leucine Rich repeat SM-ATX PF14438.6 ORY88043.1 - 0.067 13.3 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Calmodulin_bind PF07887.11 ORY88043.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 Calmodulin binding protein-like BPL_C PF02237.17 ORY88043.1 - 0.2 11.6 0.2 0.37 10.7 0.2 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain RA PF00788.23 ORY88044.1 - 1.3e-11 44.9 0.0 2.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 ORY88044.1 - 4.9e-11 42.6 0.0 8.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 ORY88044.1 - 3.9e-10 39.2 0.0 2.4e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain SAM_1 PF00536.30 ORY88044.1 - 1.2e-05 25.7 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 ORY88044.1 - 3.2e-05 23.7 0.1 0.009 15.9 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SAM_4 PF18017.1 ORY88044.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HATPase_c PF02518.26 ORY88045.1 - 6e-21 75.0 0.1 1.3e-20 73.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY88045.1 - 9e-12 45.2 0.0 2.9e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY88045.1 - 2e-07 30.9 0.2 6.2e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain NAD_binding_10 PF13460.6 ORY88046.1 - 4.4e-25 88.6 0.0 5.3e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY88046.1 - 3.7e-06 26.7 0.0 5.4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY88046.1 - 0.008 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORY88046.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY88047.1 - 5.4e-11 42.7 0.0 9.4e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY88047.1 - 3.9e-10 39.6 0.0 9.4e-10 38.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY88047.1 - 7.1e-08 31.8 0.0 1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORY88047.1 - 3.6e-05 23.4 0.1 0.00026 20.6 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 ORY88047.1 - 0.0016 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ORY88047.1 - 0.002 17.3 0.0 0.0028 16.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY88047.1 - 0.009 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PBP PF01161.20 ORY88047.1 - 0.082 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein TatD_DNase PF01026.21 ORY88049.1 - 1.6e-48 165.3 0.0 2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase COQ9 PF08511.11 ORY88052.1 - 9.5e-08 31.7 0.0 1.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 COQ9 NAD_binding_8 PF13450.6 ORY88053.1 - 2.1e-11 43.9 0.1 4e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY88053.1 - 2.8e-07 30.2 0.0 2.1e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase STAT1_TAZ2bind PF12162.8 ORY88053.1 - 7 6.3 9.5 13 5.5 2.1 2.5 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Histone_H2A_C PF16211.5 ORY88054.1 - 1.8e-14 53.2 0.5 2.6e-14 52.6 0.5 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY88054.1 - 3.1e-12 47.0 0.0 3.4e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY88054.1 - 3.2e-05 24.1 0.0 4.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2OG-FeII_Oxy PF03171.20 ORY88055.1 - 7.4e-13 48.9 0.0 1.4e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 ORY88056.1 - 3.3e-06 27.1 13.8 5.7e-06 26.3 13.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAAG1 PF15354.6 ORY88056.1 - 0.002 18.6 1.6 0.19 12.3 0.9 3.1 2 0 0 2 2 2 1 Kidney-associated antigen 1 PALP PF00291.25 ORY88057.1 - 3.7e-67 226.8 1.6 4.1e-67 226.6 1.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PX PF00787.24 ORY88059.1 - 3.1e-15 56.2 0.0 4.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 PX domain UCH PF00443.29 ORY88062.1 - 1.3e-52 178.8 0.0 1.5e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY88062.1 - 2.6e-15 56.8 0.0 3.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-MIZ PF02891.20 ORY88062.1 - 0.037 13.8 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger TPR_2 PF07719.17 ORY88064.1 - 0.0017 18.3 0.1 0.0042 17.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY88064.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 TPR repeat F-box-like PF12937.7 ORY88064.1 - 0.0074 16.2 3.5 0.14 12.1 3.5 2.5 1 1 0 1 1 1 1 F-box-like MIT PF04212.18 ORY88064.1 - 0.0079 16.2 0.2 0.021 14.9 0.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 ORY88064.1 - 0.095 12.6 0.0 0.32 10.9 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.16 ORY88065.1 - 5.4e-29 101.2 30.5 5.4e-29 101.2 30.5 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY88065.1 - 1.6e-08 33.9 12.3 4.7e-05 22.4 0.0 3.4 2 1 1 3 3 3 3 Sugar (and other) transporter F-box-like PF12937.7 ORY88066.1 - 0.0031 17.4 0.5 0.006 16.4 0.5 1.5 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 ORY88067.1 - 9.2e-55 185.8 0.0 1.1e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88067.1 - 2.2e-23 82.9 0.3 1.1e-22 80.6 0.3 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY88067.1 - 5e-07 29.3 0.0 9.4e-06 25.1 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 ORY88067.1 - 0.00082 18.8 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY88067.1 - 0.0058 16.3 1.1 0.012 15.2 0.9 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 ORY88067.1 - 0.016 15.1 0.0 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family IF3_N PF05198.16 ORY88069.1 - 5.9e-07 29.7 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 ORY88069.1 - 5e-06 26.3 0.0 8.9e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_C PF00707.22 ORY88069.1 - 2.6e-05 24.1 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain F-box-like PF12937.7 ORY88070.1 - 0.0039 17.1 0.4 0.0076 16.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like DEAD PF00270.29 ORY88071.1 - 2.3e-49 167.5 0.0 9e-49 165.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY88071.1 - 2.8e-28 98.5 0.0 1.3e-27 96.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY88071.1 - 0.0019 18.3 0.0 0.0062 16.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit F-box-like PF12937.7 ORY88072.1 - 0.0083 16.0 0.6 0.033 14.1 0.6 2.2 1 0 0 1 1 1 1 F-box-like COesterase PF00135.28 ORY88073.1 - 4.6e-85 286.4 0.0 6.3e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY88073.1 - 2.9e-10 40.4 0.2 4.1e-09 36.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold MutS_V PF00488.21 ORY88074.1 - 8e-68 228.2 0.1 1.6e-67 227.2 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY88074.1 - 2e-36 126.0 0.1 5.5e-36 124.6 0.1 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 ORY88074.1 - 7.9e-33 113.1 0.0 2.4e-32 111.5 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 ORY88074.1 - 3.8e-12 46.7 0.2 2.3e-10 40.9 0.0 2.9 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ORY88074.1 - 1.8e-09 37.8 0.4 4.2e-09 36.6 0.4 1.7 1 0 0 1 1 1 1 MutS family domain IV ABC_tran PF00005.27 ORY88074.1 - 0.015 15.8 0.0 0.062 13.8 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 ORY88074.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 ORY88074.1 - 0.08 12.5 0.0 0.3 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF334 PF03904.13 ORY88074.1 - 0.15 11.5 0.0 0.53 9.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF334) AAA_23 PF13476.6 ORY88074.1 - 0.32 11.5 0.0 0.32 11.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain Rad51 PF08423.11 ORY88075.1 - 2.5e-13 49.9 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 ORY88075.1 - 1.5e-06 28.0 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY88075.1 - 0.0018 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 ORY88075.1 - 0.026 14.2 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 ORY88075.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein IstB_IS21 PF01695.17 ORY88075.1 - 0.058 13.1 0.1 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein MFS_1 PF07690.16 ORY88077.1 - 5.5e-07 28.8 12.8 5.7e-07 28.8 12.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily SpoVAB PF13782.6 ORY88077.1 - 0.016 15.5 0.7 0.02 15.2 0.7 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AB Phage_holin_2_4 PF16082.5 ORY88077.1 - 0.049 13.4 1.2 0.083 12.6 0.1 1.9 1 1 1 2 2 2 0 Bacteriophage holin family, superfamily II-like F-box-like PF12937.7 ORY88078.1 - 6.3e-08 32.4 2.0 1.5e-07 31.2 2.0 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 ORY88080.1 - 1.7e-31 107.7 28.8 9.8e-06 26.2 0.5 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY88080.1 - 2.5e-15 56.5 1.0 0.0067 16.7 0.0 6.7 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 ORY88080.1 - 1.5e-07 31.2 1.7 2e-07 30.8 0.4 1.9 2 0 0 2 2 2 1 F-box-like WD40_like PF17005.5 ORY88080.1 - 6.1e-06 25.8 0.1 0.034 13.5 0.0 2.7 2 1 2 4 4 4 3 WD40-like domain Nup160 PF11715.8 ORY88080.1 - 0.00028 19.7 3.4 0.19 10.4 0.0 4.5 3 1 2 5 5 5 1 Nucleoporin Nup120/160 F-box PF00646.33 ORY88080.1 - 0.0024 17.7 0.2 0.0052 16.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain Kelch_6 PF13964.6 ORY88080.1 - 0.098 13.0 4.2 8.8 6.8 0.2 4.0 3 1 1 4 4 4 0 Kelch motif Vezatin PF12632.7 ORY88081.1 - 1.7e-10 40.8 0.0 8.2e-08 31.9 0.0 2.5 2 0 0 2 2 2 2 Mysoin-binding motif of peroxisomes MFS_1 PF07690.16 ORY88082.1 - 1.1e-31 110.1 27.7 1.1e-31 110.1 27.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 ORY88082.1 - 0.084 12.6 1.4 2.9 7.7 0.6 2.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Phage_holin_5_2 PF16079.5 ORY88082.1 - 1.5 9.2 10.1 0.74 10.2 1.6 4.0 2 2 0 3 3 3 0 Phage holin family Hol44, in holin superfamily V MFS_1 PF07690.16 ORY88083.1 - 6.9e-34 117.3 54.2 6.9e-34 117.3 54.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY88083.1 - 2.1e-07 29.8 22.8 2.9e-07 29.3 22.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RhodobacterPufX PF11511.8 ORY88083.1 - 0.39 10.3 9.7 3.9 7.2 0.2 4.6 2 1 1 3 3 3 0 Intrinsic membrane protein PufX GST_N_3 PF13417.6 ORY88084.1 - 1.8e-05 25.0 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY88084.1 - 3.3e-05 24.0 0.0 8.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY88084.1 - 3.6e-05 23.9 0.2 0.00056 20.1 0.0 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY88084.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY88084.1 - 0.0035 17.6 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY88084.1 - 0.0038 17.2 0.0 0.0079 16.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SMN PF06003.12 ORY88086.1 - 0.064 12.5 2.1 0.084 12.1 2.1 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) COPI_C PF06957.11 ORY88086.1 - 0.079 11.7 2.2 0.095 11.4 2.2 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ANAPC15 PF15243.6 ORY88086.1 - 1.7 9.1 6.5 3.4 8.1 6.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 UreD PF01774.17 ORY88088.1 - 0.035 14.0 0.2 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 UreD urease accessory protein Pkinase PF00069.25 ORY88089.1 - 3.8e-64 216.6 0.0 4.7e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88089.1 - 4.5e-32 111.3 0.0 5.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 ORY88089.1 - 0.00047 20.4 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 2 C2 domain FTA2 PF13095.6 ORY88089.1 - 0.0013 18.4 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORY88089.1 - 0.0021 17.5 0.0 0.081 12.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY88089.1 - 0.052 12.5 0.0 0.12 11.3 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain CUE PF02845.16 ORY88091.1 - 0.00016 21.3 0.7 0.18 11.5 0.0 3.5 4 0 0 4 4 4 2 CUE domain DASH_Spc34 PF08657.10 ORY88092.1 - 1.2e-08 35.1 4.5 3.4e-05 23.8 1.7 2.8 1 1 1 2 2 2 2 DASH complex subunit Spc34 Ntox28 PF15605.6 ORY88092.1 - 0.029 14.6 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial toxin 28 Ndc1_Nup PF09531.10 ORY88092.1 - 4.9 5.7 8.2 7.8 5.0 8.2 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zn_clus PF00172.18 ORY88093.1 - 1.2e-06 28.5 5.6 2.1e-06 27.7 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sporozoite_P67 PF05642.11 ORY88093.1 - 8.3 4.4 7.4 15 3.5 7.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RTA1 PF04479.13 ORY88094.1 - 3.3e-51 173.9 7.4 4.2e-51 173.5 7.4 1.1 1 0 0 1 1 1 1 RTA1 like protein A_deamin PF02137.18 ORY88095.1 - 1.8e-38 132.8 0.0 1.7e-23 83.6 0.0 2.1 2 0 0 2 2 2 2 Adenosine-deaminase (editase) domain PAP2 PF01569.21 ORY88096.1 - 1.3e-26 92.9 1.4 2.5e-26 92.1 1.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 ORY88096.1 - 0.023 14.4 4.1 0.15 11.7 0.3 2.5 2 1 1 3 3 3 0 PAP2 superfamily F-box-like PF12937.7 ORY88098.1 - 9.3e-05 22.3 0.2 0.00016 21.5 0.2 1.4 1 0 0 1 1 1 1 F-box-like RVT_3 PF13456.6 ORY88100.1 - 0.00048 19.9 0.0 0.00095 19.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like RVT_1 PF00078.27 ORY88100.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SRP54 PF00448.22 ORY88103.1 - 1.8e-47 161.5 0.1 2.6e-30 105.6 0.1 2.4 2 1 0 2 2 2 2 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 ORY88103.1 - 1.8e-38 133.2 3.6 1.7e-36 126.7 3.6 2.2 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 ORY88103.1 - 1.6e-05 25.0 0.0 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 ORY88103.1 - 0.00016 20.8 0.1 0.00075 18.6 0.1 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORY88103.1 - 0.005 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ORY88103.1 - 0.0066 16.5 0.0 0.052 13.6 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 ORY88103.1 - 0.0067 16.7 0.0 0.26 11.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 ORY88103.1 - 0.013 14.7 0.0 0.84 8.7 0.0 2.4 2 0 0 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.15 ORY88103.1 - 0.11 12.4 0.5 0.53 10.2 0.2 2.3 2 1 0 2 2 2 0 NTPase AAA_31 PF13614.6 ORY88103.1 - 0.14 12.1 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bmt2 PF11968.8 ORY88104.1 - 1.8e-60 204.6 0.0 2.9e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 ORY88104.1 - 1.8e-05 24.6 0.0 2.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY88104.1 - 0.0015 19.1 0.0 0.0031 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY88104.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORY88104.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.6 ORY88104.1 - 0.046 14.4 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain COesterase PF00135.28 ORY88106.1 - 1.7e-89 301.1 0.0 2.2e-89 300.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY88106.1 - 2.8e-10 40.4 0.3 3.2e-09 37.0 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold ADIP PF11559.8 ORY88107.1 - 4.7e-14 52.7 7.0 4.7e-14 52.7 7.0 2.6 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 ORY88107.1 - 0.54 9.5 19.6 1.5 8.1 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2951 PF11166.8 ORY88107.1 - 4.9 7.4 5.9 2.9 8.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Spc7 PF08317.11 ORY88107.1 - 5.7 5.7 22.6 0.18 10.6 2.4 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF2408 PF10303.9 ORY88107.1 - 6.7 7.3 14.4 0.15 12.7 0.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) MFS_1 PF07690.16 ORY88108.1 - 9.3e-35 120.2 29.5 9.3e-35 120.2 29.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4014 PF13198.6 ORY88108.1 - 0.38 11.2 7.0 1.4 9.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) MFS_1 PF07690.16 ORY88109.1 - 6.4e-23 81.2 20.9 6.6e-23 81.2 20.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TFIIB PF00382.19 ORY88110.1 - 2.5e-37 126.7 0.3 5.9e-18 64.7 0.1 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 ORY88110.1 - 4.5e-27 94.3 1.2 4.5e-27 94.3 1.2 3.4 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 ORY88110.1 - 2.4e-07 30.2 1.7 7.6e-07 28.6 1.7 2.0 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ORY88110.1 - 0.0016 18.2 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-RRN7 PF11781.8 ORY88110.1 - 5.8 6.7 5.2 0.66 9.7 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Nudix_N_2 PF14803.6 ORY88110.1 - 6.8 6.7 7.4 0.69 9.9 2.0 2.2 2 0 0 2 2 2 0 Nudix N-terminal DUF3246 PF11596.8 ORY88110.1 - 8.7 5.7 9.9 3.2 7.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) GMC_oxred_N PF00732.19 ORY88111.1 - 4.5e-64 216.7 0.0 7.6e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY88111.1 - 7.4e-32 110.9 0.0 1.3e-31 110.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 ORY88111.1 - 1.3e-06 27.7 0.4 2.3e-06 26.9 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY88111.1 - 0.00031 19.9 0.0 0.00086 18.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 ORY88111.1 - 0.00073 18.9 0.1 0.0019 17.5 0.1 1.7 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORY88111.1 - 0.0011 19.1 0.7 0.0037 17.5 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY88111.1 - 0.0027 17.4 2.8 0.015 14.9 2.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY88111.1 - 0.012 14.8 0.2 0.035 13.4 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY88111.1 - 0.016 13.9 0.2 0.028 13.1 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Maf_N PF08383.11 ORY88111.1 - 0.16 11.8 0.2 0.34 10.7 0.2 1.5 1 0 0 1 1 1 0 Maf N-terminal region GIDA PF01134.22 ORY88111.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY88111.1 - 0.18 12.4 0.3 0.62 10.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase START PF01852.19 ORY88112.1 - 4.9e-16 58.8 0.1 1.9e-09 37.2 0.0 3.8 4 0 0 4 4 4 2 START domain GNAT_like PF18407.1 ORY88112.1 - 0.0068 16.7 0.2 0.052 13.9 0.2 2.7 1 0 0 1 1 1 1 GCN5-related N-acetyltransferase like domain AF-4 PF05110.13 ORY88114.1 - 3.9 5.5 5.6 5 5.1 5.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SRF-TF PF00319.18 ORY88115.1 - 4.6e-25 86.9 0.1 7.4e-25 86.2 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SUIM_assoc PF16619.5 ORY88115.1 - 0.00023 21.2 4.6 0.85 9.7 4.6 2.9 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 ORY88115.1 - 0.0063 16.6 11.4 0.0081 16.2 11.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PRCH PF03967.13 ORY88115.1 - 0.84 9.9 3.7 0.23 11.7 0.7 1.5 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region Activator_LAG-3 PF11498.8 ORY88115.1 - 1.2 8.0 29.4 2.1 7.2 29.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 ORY88115.1 - 2.6 7.6 17.6 4.1 6.9 17.6 1.3 1 0 0 1 1 1 0 Spt20 family MFS_1 PF07690.16 ORY88117.1 - 1.4e-31 109.7 44.6 5.3e-30 104.5 27.5 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_11 PF13414.6 ORY88118.1 - 4e-10 39.2 0.5 8.9e-08 31.7 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 ORY88118.1 - 9.3e-08 31.6 0.7 0.0006 19.5 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY88118.1 - 5.8e-06 26.0 6.6 0.0023 17.9 0.1 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY88118.1 - 7.3e-05 23.2 0.5 0.12 12.9 0.2 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY88118.1 - 0.00016 22.2 1.2 0.014 16.0 0.1 3.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY88118.1 - 0.0016 18.7 0.1 0.16 12.4 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY88118.1 - 0.0024 17.9 0.0 8.6 6.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY88118.1 - 0.0093 16.7 0.7 5 8.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY88118.1 - 0.033 14.3 0.6 0.12 12.5 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3408 PF11888.8 ORY88118.1 - 0.053 13.7 5.2 0.11 12.6 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) TPR_3 PF07720.12 ORY88118.1 - 0.06 13.4 0.6 1.4 9.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Menin PF05053.13 ORY88118.1 - 0.25 9.7 2.4 0.33 9.3 2.4 1.1 1 0 0 1 1 1 0 Menin CDC45 PF02724.14 ORY88118.1 - 1.6 6.9 4.5 2.1 6.5 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORY88118.1 - 6.6 6.5 10.1 11 5.7 10.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DnaJ PF00226.31 ORY88119.1 - 2.4e-09 37.2 0.0 2.9e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain F-box-like PF12937.7 ORY88120.1 - 0.0013 18.5 0.6 0.0032 17.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 ORY88120.1 - 0.076 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeat Ank_2 PF12796.7 ORY88121.1 - 2.8e-07 31.0 0.1 0.0031 18.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY88121.1 - 4e-05 23.8 0.3 0.24 11.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY88121.1 - 0.0002 21.8 0.3 0.0024 18.4 0.1 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY88121.1 - 0.0022 18.4 3.5 0.069 13.6 0.4 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORY88121.1 - 0.038 14.5 3.2 1.8 9.4 0.1 3.4 4 0 0 4 4 4 0 Ankyrin repeat Oxidored_FMN PF00724.20 ORY88122.1 - 1.4e-59 202.1 0.0 1.8e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldedh PF00171.22 ORY88124.1 - 2.3e-79 267.0 0.0 3.3e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 ORY88125.1 - 7.2e-28 96.3 15.3 0.00047 20.9 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORY88125.1 - 0.0021 17.1 0.1 1.2 8.0 0.0 2.6 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY88125.1 - 0.052 12.2 0.2 9.3 4.8 0.0 2.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 FF PF01846.19 ORY88126.1 - 1.3e-36 124.6 15.1 1e-09 38.4 0.2 7.0 6 1 0 6 6 6 5 FF domain WW PF00397.26 ORY88126.1 - 1.9e-11 43.9 15.9 1.2e-05 25.2 6.0 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 ORY88126.1 - 0.00023 21.8 0.0 1.3 9.8 0.0 3.6 3 0 0 3 3 3 2 p190-A and -B Rho GAPs FF domain Jak1_Phl PF17887.1 ORY88126.1 - 7.7 6.5 8.2 4.9 7.1 5.1 2.4 1 1 1 2 2 2 0 Jak1 pleckstrin homology-like domain Transp_cyt_pur PF02133.15 ORY88127.1 - 4.8e-79 266.2 31.3 5.4e-79 266.0 31.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ARD PF03079.14 ORY88129.1 - 2.2e-43 148.1 0.1 2.6e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 ORY88129.1 - 9.8e-09 34.8 0.5 8.3e-08 31.8 0.0 2.3 3 0 0 3 3 3 1 Cupin domain AraC_binding PF02311.19 ORY88129.1 - 5.4e-07 29.6 0.0 7.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain GPI-anchored PF10342.9 ORY88130.1 - 4.3e-08 33.8 1.0 4.3e-08 33.8 1.0 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Histone PF00125.24 ORY88131.1 - 1.9e-41 141.5 0.0 2.5e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY88131.1 - 9.3e-06 25.7 0.1 1.4e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY88131.1 - 0.0012 19.1 0.2 0.0019 18.5 0.2 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 ORY88131.1 - 0.031 14.5 0.3 0.086 13.1 0.3 1.7 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CTNNB1_binding PF08347.11 ORY88134.1 - 0.042 14.0 1.8 0.04 14.1 1.8 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding SRR1 PF07985.12 ORY88134.1 - 0.13 12.3 0.4 18 5.5 0.0 2.3 2 0 0 2 2 2 0 SRR1 ParA PF10609.9 ORY88135.1 - 3.1e-93 311.8 0.0 3.6e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY88135.1 - 8.8e-09 35.5 0.0 3.2e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 ORY88135.1 - 4.1e-06 26.2 0.3 0.00017 20.9 0.1 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 ORY88135.1 - 2.8e-05 24.1 0.1 0.0014 18.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 ORY88135.1 - 0.0024 17.4 0.0 2.2 7.7 0.0 2.4 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 ORY88135.1 - 0.005 16.4 0.1 0.014 14.9 0.1 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 ORY88135.1 - 0.026 14.5 0.0 0.058 13.3 0.0 1.5 2 0 0 2 2 2 0 RsgA GTPase SelB-wing_3 PF09107.11 ORY88135.1 - 0.03 14.0 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix AAA_26 PF13500.6 ORY88135.1 - 0.036 13.9 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY88135.1 - 0.063 12.5 0.1 0.097 11.8 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 ORY88135.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MipZ PF09140.11 ORY88135.1 - 0.12 11.6 0.0 0.26 10.6 0.0 1.5 1 1 0 1 1 1 0 ATPase MipZ PcrB PF01884.17 ORY88135.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 PcrB family Mito_carr PF00153.27 ORY88136.1 - 1e-50 169.6 0.0 3.2e-18 65.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HSF_DNA-bind PF00447.17 ORY88138.1 - 1.4e-26 92.9 0.3 1.5e-26 92.8 0.3 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding zf-MYND PF01753.18 ORY88139.1 - 0.00018 21.5 9.5 0.00045 20.3 9.5 1.7 1 0 0 1 1 1 1 MYND finger Glyco_transf_90 PF05686.12 ORY88140.1 - 3.2e-20 72.4 0.2 7.5e-20 71.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 DPPIV_N PF00930.21 ORY88141.1 - 1.8e-74 250.7 0.0 2.3e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORY88141.1 - 8.3e-38 130.0 0.5 1.9e-37 128.8 0.5 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY88141.1 - 1.1e-05 25.2 0.1 2.6e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 ORY88141.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.12 ORY88141.1 - 0.058 12.1 0.0 0.16 10.6 0.0 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) LIP PF03583.14 ORY88141.1 - 0.2 10.9 0.1 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Secretory lipase PCNA_N PF00705.18 ORY88142.1 - 6.8e-54 181.0 5.0 4.2e-53 178.4 3.5 2.5 3 0 0 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ORY88142.1 - 8.9e-42 142.3 1.2 7.1e-20 71.5 0.0 3.4 3 1 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 ORY88142.1 - 2.2e-07 30.2 2.2 4.8e-06 25.8 0.2 2.7 2 1 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 ORY88142.1 - 0.017 14.6 0.1 0.042 13.3 0.0 1.7 2 1 0 2 2 2 0 Rad9 LAP1C PF05609.12 ORY88142.1 - 0.35 9.9 18.8 0.48 9.5 18.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TFIIF_alpha PF05793.12 ORY88142.1 - 0.65 8.5 42.3 0.87 8.1 42.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) eIF-3c_N PF05470.12 ORY88142.1 - 1.7 6.9 18.1 2.5 6.3 18.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AF-4 PF05110.13 ORY88142.1 - 1.7 6.6 24.7 2.1 6.3 24.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-MYND PF01753.18 ORY88143.1 - 0.00038 20.5 9.6 0.00089 19.3 9.6 1.7 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.7 ORY88144.1 - 0.0038 17.1 1.3 0.0061 16.4 1.3 1.4 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.7 ORY88145.1 - 1.8e-08 34.9 0.1 2.9e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY88145.1 - 3.7e-07 30.6 0.0 7.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY88145.1 - 0.0001 22.4 0.0 0.00051 20.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 ORY88145.1 - 0.0003 21.1 0.0 0.00064 20.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 ORY88145.1 - 0.00089 19.5 0.1 0.0021 18.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 ORY88145.1 - 0.0036 18.0 0.0 0.5 11.1 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Pex14_N PF04695.13 ORY88147.1 - 3.2 8.4 10.7 4.3 8.0 10.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.9 ORY88147.1 - 4.3 6.4 14.9 4.9 6.2 14.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIF_alpha PF05793.12 ORY88147.1 - 7.9 4.9 9.2 8.1 4.9 9.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Carb_kinase PF01256.17 ORY88149.1 - 1.1e-56 192.1 0.0 1.3e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 ORY88149.1 - 0.00094 18.6 0.0 0.0016 17.9 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Mac PF12464.8 ORY88149.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Maltose acetyltransferase F-box-like PF12937.7 ORY88151.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.7 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.7 ORY88152.1 - 4.9e-05 23.1 0.2 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY88152.1 - 0.02 14.8 0.2 15 5.6 0.0 3.6 3 0 0 3 3 3 0 F-box domain DUF272 PF03312.15 ORY88152.1 - 0.17 12.1 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF272) SKG6 PF08693.10 ORY88153.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 ORY88153.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) MAP65_ASE1 PF03999.12 ORY88154.1 - 5.2 5.7 6.0 6.3 5.4 6.0 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FAD_binding_3 PF01494.19 ORY88156.1 - 1.9e-11 43.8 3.6 2.6e-10 40.1 3.6 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY88156.1 - 6.4e-08 32.7 0.1 4.5e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ORY88156.1 - 0.00014 21.3 0.5 0.035 13.4 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY88156.1 - 0.0025 16.8 0.5 0.0052 15.7 0.5 1.5 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.6 ORY88156.1 - 0.0044 17.2 0.6 0.012 15.8 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORY88156.1 - 0.074 12.3 2.2 0.1 11.9 1.6 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORY88156.1 - 0.12 11.9 1.4 0.29 10.7 0.7 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY88156.1 - 0.48 9.5 4.2 0.71 8.9 4.0 1.4 1 1 0 1 1 1 0 FAD binding domain DUF727 PF05303.12 ORY88157.1 - 0.013 15.6 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF727) RabGAP-TBC PF00566.18 ORY88159.1 - 1.5e-25 90.2 1.3 1.9e-25 89.8 1.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Dynamin_M PF01031.20 ORY88161.1 - 1.2e-108 362.7 0.0 1.7e-108 362.2 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 ORY88161.1 - 8.9e-53 178.8 0.0 1.6e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY88161.1 - 3.9e-29 100.6 1.0 9.7e-29 99.4 0.7 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY88161.1 - 0.0015 18.6 0.0 0.0083 16.2 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase TipAS PF07739.13 ORY88161.1 - 0.051 14.1 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Phage_holin_2_4 PF16082.5 ORY88162.1 - 0.17 11.6 2.1 0.63 9.8 0.5 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like PV-1 PF06637.11 ORY88163.1 - 0.19 10.5 1.4 0.22 10.3 1.4 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Amnionless PF14828.6 ORY88164.1 - 0.036 12.9 0.1 0.053 12.3 0.1 1.2 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.9 ORY88164.1 - 0.038 12.8 0.1 0.053 12.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RIFIN PF02009.16 ORY88164.1 - 0.18 11.7 6.5 0.29 11.0 6.5 1.3 1 0 0 1 1 1 0 Rifin PV-1 PF06637.11 ORY88166.1 - 0.2 10.4 0.8 0.28 10.0 0.8 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) FAM220 PF15487.6 ORY88166.1 - 0.22 11.1 5.8 0.3 10.7 5.8 1.1 1 0 0 1 1 1 0 FAM220 family CCDC24 PF15669.5 ORY88166.1 - 2.4 8.0 11.7 0.11 12.4 5.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Sortilin-Vps10 PF15902.5 ORY88169.1 - 6.4e-301 997.5 4.7 6.5e-154 513.0 0.4 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 ORY88169.1 - 2e-92 308.1 10.5 8.7e-48 162.9 1.1 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 ORY88169.1 - 7.8e-05 22.1 41.1 0.12 12.4 0.2 11.5 11 0 0 11 11 11 3 BNR/Asp-box repeat CHB_HEX_C PF03174.13 ORY88169.1 - 0.0015 18.5 7.0 10 6.2 0.0 6.0 8 0 0 8 8 8 2 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 ORY88169.1 - 0.011 15.1 7.7 2.9 7.0 0.2 5.0 5 1 0 5 5 5 0 Photosynthesis system II assembly factor YCF48 UCR_UQCRX_QCR9 PF05365.12 ORY88169.1 - 0.16 11.9 3.7 3.3 7.7 0.3 3.6 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like BNR_6 PF15899.5 ORY88169.1 - 1.3 9.3 5.0 5.9 7.2 0.8 3.8 3 0 0 3 3 3 0 BNR-Asp box repeat adh_short PF00106.25 ORY88170.1 - 2e-39 135.1 0.9 4.4e-39 134.0 0.9 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88170.1 - 7.3e-36 123.9 0.4 2e-34 119.1 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY88170.1 - 1.6e-11 44.4 0.7 6.6e-08 32.7 0.3 2.3 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 ORY88170.1 - 3.8e-05 22.8 0.3 0.00017 20.7 0.3 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 ORY88170.1 - 0.0031 16.9 0.3 0.0049 16.2 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.21 ORY88170.1 - 0.031 13.7 0.2 0.055 12.9 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 ORY88171.1 - 1.4e-07 31.5 4.2 2.3e-07 30.8 4.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 ORY88172.1 - 2.2e-12 47.5 0.1 5.3e-12 46.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 ORY88172.1 - 5.6e-11 42.4 0.0 8.4e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORY88172.1 - 1.2e-10 41.4 0.1 2.4e-10 40.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY88172.1 - 9e-09 35.9 0.0 2.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY88172.1 - 2.6e-07 30.6 0.0 7.3e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY88172.1 - 6.2e-06 25.4 0.1 9.2e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ORY88172.1 - 1.5e-05 24.4 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 ORY88172.1 - 2.6e-05 24.2 0.2 4.2e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY88172.1 - 5e-05 24.0 0.0 9.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY88172.1 - 5.8e-05 22.7 0.1 0.0001 21.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 ORY88172.1 - 0.0049 16.6 0.1 0.0074 16.0 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 ORY88172.1 - 0.0075 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY88172.1 - 0.0082 15.9 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 ORY88172.1 - 0.0092 16.1 0.0 0.034 14.3 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase PRMT5 PF05185.16 ORY88172.1 - 0.014 15.2 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TehB PF03848.14 ORY88172.1 - 0.022 14.1 0.5 0.092 12.1 0.5 1.9 1 1 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 ORY88172.1 - 0.03 13.8 0.1 0.053 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.16 ORY88172.1 - 0.033 13.9 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.6 ORY88172.1 - 0.042 14.9 0.0 0.13 13.3 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 ORY88172.1 - 0.053 13.1 0.1 0.09 12.3 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 ORY88172.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2796 PF10986.8 ORY88173.1 - 0.35 10.8 5.6 0.36 10.8 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) Tfb2 PF03849.14 ORY88174.1 - 1.4e-126 422.2 0.0 1.7e-126 422.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 ORY88174.1 - 9.2e-26 90.1 0.0 1.8e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 ORY88174.1 - 0.0041 17.3 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain dCMP_cyt_deam_1 PF00383.23 ORY88175.1 - 1.6e-14 53.6 0.0 2.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ORY88175.1 - 6.4e-10 39.3 0.5 2.2e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ORY88175.1 - 0.00028 20.5 0.9 0.21 11.2 0.1 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases efThoc1 PF11957.8 ORY88179.1 - 1.4e-25 90.0 0.0 1.5e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor DUF1192 PF06698.11 ORY88184.1 - 0.006 16.6 1.3 0.012 15.7 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) HalX PF08663.10 ORY88184.1 - 0.028 14.7 0.7 0.042 14.2 0.7 1.2 1 0 0 1 1 1 0 HalX domain Myco_arth_vir_N PF09610.10 ORY88184.1 - 0.051 13.7 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Spc29 PF17082.5 ORY88184.1 - 0.2 11.5 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 TPR_11 PF13414.6 ORY88185.1 - 0.0005 19.7 0.9 0.81 9.4 0.0 4.7 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 ORY88185.1 - 0.02 15.3 0.4 10 6.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY88185.1 - 0.1 12.8 12.6 33 4.9 0.3 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY88185.1 - 0.12 12.2 4.6 2.8 7.9 0.2 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Catalase PF00199.19 ORY88187.1 - 9.4e-24 84.2 0.1 4.5e-14 52.3 0.1 2.1 1 1 1 2 2 2 2 Catalase Na_sulph_symp PF00939.19 ORY88187.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Sodium:sulfate symporter transmembrane region Helicase_C PF00271.31 ORY88188.1 - 2.7e-20 72.8 0.0 5.1e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY88188.1 - 3.8e-19 69.3 0.0 7.6e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY88188.1 - 5.5e-16 58.8 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1115 PF06544.12 ORY88190.1 - 1.8e-11 44.4 0.0 7.1e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) 2-Hacid_dh_C PF02826.19 ORY88192.1 - 6e-48 162.6 0.0 9.4e-48 161.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY88192.1 - 1.1e-16 60.8 0.0 9.4e-16 57.7 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GLE1 PF07817.13 ORY88196.1 - 7.5e-67 225.2 0.0 1.1e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein Casc1_N PF15927.5 ORY88196.1 - 2.8e-06 27.2 14.4 2.8e-06 27.2 14.4 2.4 1 1 1 2 2 2 1 Cancer susceptibility candidate 1 N-terminus SspB PF04386.13 ORY88196.1 - 1.2 9.0 7.1 2.6 7.9 7.1 1.5 1 0 0 1 1 1 0 Stringent starvation protein B RR_TM4-6 PF06459.12 ORY88196.1 - 2.6 7.8 16.5 4.4 7.1 16.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 ORY88196.1 - 6 7.2 16.9 14 6.0 16.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 AAA_23 PF13476.6 ORY88196.1 - 7.4 7.0 12.0 12 6.4 12.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.14 ORY88196.1 - 8.5 6.8 9.4 5.3 7.5 6.5 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Paf1 PF03985.13 ORY88196.1 - 8.5 5.3 21.3 14 4.5 21.3 1.2 1 0 0 1 1 1 0 Paf1 DDRGK PF09756.9 ORY88196.1 - 9.1 5.8 30.8 15 5.2 30.8 1.3 1 0 0 1 1 1 0 DDRGK domain MAP65_ASE1 PF03999.12 ORY88197.1 - 1.2e-61 209.2 4.3 1.8e-61 208.6 4.3 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Cir_N PF10197.9 ORY88200.1 - 0.017 15.3 0.1 0.017 15.3 0.1 3.8 6 0 0 6 6 6 0 N-terminal domain of CBF1 interacting co-repressor CIR UCMA PF17085.5 ORY88200.1 - 1.3 9.1 10.6 0.92 9.5 8.2 2.0 2 0 0 2 2 2 0 Unique cartilage matrix associated protein Mo25 PF08569.11 ORY88202.1 - 6.7e-132 439.8 9.1 7.5e-132 439.6 9.1 1.0 1 0 0 1 1 1 1 Mo25-like Sel1 PF08238.12 ORY88203.1 - 1.5e-48 162.1 14.4 6.2e-09 36.2 0.3 7.7 7 0 0 7 7 7 7 Sel1 repeat TPR_11 PF13414.6 ORY88203.1 - 4.5 7.1 9.5 1.1 9.0 0.1 3.7 4 0 0 4 4 4 0 TPR repeat Sec61_beta PF03911.16 ORY88204.1 - 4.4e-16 58.6 0.3 6.8e-16 58.0 0.3 1.3 1 0 0 1 1 1 1 Sec61beta family Pmp3 PF01679.17 ORY88205.1 - 4.2e-14 52.5 7.6 5.2e-14 52.2 7.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator COesterase PF00135.28 ORY88206.1 - 4.6e-83 279.8 0.0 5.6e-83 279.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY88206.1 - 0.00022 21.2 0.1 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY88206.1 - 0.0031 17.0 0.1 0.0049 16.4 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family LRR_4 PF12799.7 ORY88207.1 - 3 8.4 7.1 8.3 7.0 1.7 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) RNase_PH PF01138.21 ORY88208.1 - 4.7e-20 72.4 0.2 9.1e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY88208.1 - 4.7e-06 26.5 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ribosomal_60s PF00428.19 ORY88208.1 - 0.048 14.3 2.7 0.048 14.3 2.7 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rad60-SLD PF11976.8 ORY88209.1 - 8.4e-18 64.0 0.0 1.1e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY88209.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family MBOAT_2 PF13813.6 ORY88210.1 - 1.7e-09 37.8 2.6 1.7e-09 37.8 2.6 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Lactamase_B_2 PF12706.7 ORY88214.1 - 0.029 13.9 0.0 0.062 12.8 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CBP4 PF07960.11 ORY88215.1 - 0.31 10.9 2.4 0.62 9.9 2.4 1.4 1 0 0 1 1 1 0 CBP4 Mss4 PF04421.13 ORY88217.1 - 3.3e-14 52.8 0.0 7.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_1 PF00583.25 ORY88217.1 - 1.4e-10 41.5 0.0 2.2e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY88217.1 - 2.9e-08 33.7 0.1 5e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY88217.1 - 5.8e-07 29.6 0.0 8.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY88217.1 - 6.5e-07 29.7 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORY88217.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 ORY88217.1 - 0.034 14.3 0.1 0.063 13.4 0.1 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORY88217.1 - 0.079 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_15 PF17013.5 ORY88217.1 - 0.27 10.7 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Ras PF00071.22 ORY88218.1 - 6.1e-34 117.0 0.2 7.2e-34 116.7 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY88218.1 - 9e-26 90.4 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY88218.1 - 1.2e-08 34.6 0.0 1.5e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY88218.1 - 4.7e-07 29.4 0.3 6e-07 29.1 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 ORY88218.1 - 0.00061 18.7 0.2 0.34 9.7 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TniB PF05621.11 ORY88218.1 - 0.0058 16.1 0.0 2.1 7.7 0.0 2.4 2 1 0 2 2 2 2 Bacterial TniB protein G-alpha PF00503.20 ORY88218.1 - 0.031 13.4 1.1 0.062 12.5 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 ORY88218.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Lactamase_B_2 PF12706.7 ORY88222.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DRMBL PF07522.14 ORY88222.1 - 0.077 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Methyltransf_16 PF10294.9 ORY88223.1 - 7.8e-19 68.1 0.0 1.2e-18 67.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 ORY88223.1 - 0.00095 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY88223.1 - 0.0027 18.4 0.0 0.0069 17.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Glyoxalase_6 PF18029.1 ORY88223.1 - 0.024 15.4 0.1 0.065 14.0 0.1 1.7 1 0 0 1 1 1 0 Glyoxalase-like domain Methyltransf_12 PF08242.12 ORY88223.1 - 0.088 13.6 0.0 0.16 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ThiF PF00899.21 ORY88224.1 - 1.5e-66 224.2 0.0 2.6e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 ORY88224.1 - 1.7e-13 51.0 0.2 8.6e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 ORY88224.1 - 2.4e-13 50.6 4.2 2.9e-08 33.9 0.1 2.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 ORY88224.1 - 0.0035 17.7 0.4 0.069 13.6 0.3 3.1 4 1 0 4 4 4 1 Putative NAD(P)-binding G-alpha PF00503.20 ORY88224.1 - 0.0081 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Shikimate_DH PF01488.20 ORY88224.1 - 0.042 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY88224.1 - 0.31 11.3 2.3 2.7 8.3 2.3 2.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 ORY88225.1 - 1.1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Alpha_Helical PF18489.1 ORY88225.1 - 0.018 15.2 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Alpha helical domain Ribosomal_L18 PF17135.4 ORY88228.1 - 8.3e-88 292.7 2.7 9.9e-88 292.4 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORY88228.1 - 1.4e-05 25.7 0.0 3.7e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A AMPKBI PF04739.15 ORY88228.1 - 0.11 12.8 1.0 8.8 6.7 0.7 2.5 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain RRM_1 PF00076.22 ORY88229.1 - 4.4e-15 55.3 0.0 6.1e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY88229.1 - 0.0002 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY88229.1 - 0.054 13.4 0.0 0.098 12.5 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif VHS PF00790.19 ORY88230.1 - 2.9e-41 140.6 0.1 9.6e-41 138.9 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 ORY88230.1 - 1.3e-20 73.5 1.4 2.9e-20 72.3 0.1 2.3 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 ORY88230.1 - 0.032 13.9 2.5 0.18 11.5 0.1 3.0 3 0 0 3 3 3 0 GGA N-GAT domain Peptidase_S46 PF10459.9 ORY88230.1 - 2.9 6.4 6.4 3.9 6.0 6.4 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF1706 PF08020.11 ORY88231.1 - 0.026 14.4 0.6 0.042 13.8 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1706) Peptidase_M50B PF13398.6 ORY88232.1 - 9e-25 87.5 12.3 1.6e-24 86.6 12.3 1.3 1 0 0 1 1 1 1 Peptidase M50B-like adh_short PF00106.25 ORY88233.1 - 0.0056 16.2 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY88233.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.22 ORY88236.1 - 1e-17 63.7 0.0 2.2e-07 30.6 0.0 3.9 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N6-adenineMlase PF10237.9 ORY88238.1 - 9.1e-34 116.6 0.0 1e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Skp1_POZ PF03931.15 ORY88239.1 - 8e-05 22.7 0.0 0.00015 21.9 0.0 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Acyltransferase PF01553.21 ORY88240.1 - 9.6e-22 77.0 0.0 1.5e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY88240.1 - 1.3e-07 31.6 0.6 7.3e-07 29.2 0.2 2.1 2 0 0 2 2 2 1 Acyltransferase C-terminus Fungal_trans PF04082.18 ORY88241.1 - 6.3e-18 64.7 3.6 9.6e-18 64.2 3.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY88241.1 - 0.0005 20.1 8.9 0.00088 19.3 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 ORY88242.1 - 5.1e-24 85.2 0.1 9.4e-24 84.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORY88242.1 - 1.1e-07 31.3 0.2 1.5e-07 30.9 0.2 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ORY88242.1 - 1.6e-06 28.3 0.6 4.1e-06 26.9 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY88242.1 - 2.4e-05 23.7 1.6 0.00015 21.1 1.6 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY88242.1 - 0.00014 21.6 2.0 0.00024 20.8 1.8 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY88242.1 - 0.00052 19.5 0.1 0.00074 19.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY88242.1 - 0.00053 20.5 0.1 0.0011 19.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY88242.1 - 0.0015 17.7 5.3 0.0024 17.0 2.8 2.1 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 ORY88242.1 - 0.0072 15.5 0.9 0.012 14.7 0.9 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 ORY88242.1 - 0.013 14.8 0.5 0.07 12.4 0.1 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORY88242.1 - 0.018 14.3 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 ORY88242.1 - 0.023 13.5 3.7 2.1 7.1 1.5 3.0 2 1 1 3 3 3 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 ORY88242.1 - 0.08 12.2 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY88242.1 - 0.094 11.4 0.8 0.14 10.8 0.8 1.5 1 1 0 1 1 1 0 HI0933-like protein Ribosomal_L38e PF01781.18 ORY88243.1 - 9.6e-32 108.9 1.1 1.2e-31 108.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family 2-Hacid_dh_C PF02826.19 ORY88245.1 - 2.5e-37 127.9 0.5 2.3e-35 121.6 0.5 3.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORY88245.1 - 0.012 15.8 0.1 0.037 14.2 0.1 1.8 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ORY88245.1 - 0.057 13.5 0.1 13 5.9 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 ORY88245.1 - 0.088 12.2 0.1 0.74 9.1 0.1 2.0 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.18 ORY88245.1 - 0.14 12.0 0.8 0.22 11.4 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 ORY88245.1 - 0.16 12.3 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY88245.1 - 0.42 11.2 4.1 0.62 10.7 2.2 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NUDIX PF00293.28 ORY88246.1 - 0.00025 21.1 0.0 0.0045 17.0 0.0 2.6 1 1 0 2 2 2 1 NUDIX domain Arrestin_N PF00339.29 ORY88247.1 - 4.9e-07 29.9 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY88247.1 - 0.024 15.1 0.0 2.4 8.6 0.0 2.8 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY88247.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like Cys_Met_Meta_PP PF01053.20 ORY88248.1 - 2.2e-108 362.2 0.7 2.9e-57 193.9 0.0 4.0 1 1 1 3 3 3 3 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY88248.1 - 9.1e-05 21.8 0.0 0.00017 20.9 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY88248.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Pmp3 PF01679.17 ORY88249.1 - 1.1e-15 57.5 5.9 1.6e-15 57.0 5.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2069 PF09842.9 ORY88249.1 - 0.028 14.6 0.1 0.039 14.2 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) 2CSK_N PF08521.10 ORY88249.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Pmp3 PF01679.17 ORY88250.1 - 4e-24 84.6 8.2 4.6e-24 84.4 8.2 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1056 PF06341.11 ORY88250.1 - 0.03 14.6 0.1 0.038 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) DUF4191 PF13829.6 ORY88250.1 - 0.16 11.3 0.0 0.18 11.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Drf_FH3 PF06367.16 ORY88251.1 - 0.014 15.0 2.0 0.016 14.9 0.5 1.7 2 0 0 2 2 2 0 Diaphanous FH3 Domain DUF5446 PF17522.2 ORY88251.1 - 0.026 14.7 0.4 0.066 13.4 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) CdiI_2 PF18593.1 ORY88251.1 - 0.04 14.6 0.1 0.092 13.4 0.1 1.6 1 0 0 1 1 1 0 CdiI immunity protein RGI1 PF10843.8 ORY88251.1 - 0.048 13.3 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Respiratory growth induced protein 1 Apolipoprotein PF01442.18 ORY88251.1 - 0.26 11.2 6.7 0.12 12.2 3.0 1.9 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain ABC_tran PF00005.27 ORY88253.1 - 7.2e-41 139.9 0.0 2.1e-22 80.1 0.0 3.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY88253.1 - 1.4e-14 54.1 4.4 1.4e-05 24.6 0.0 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY88253.1 - 6.4e-14 52.4 8.7 0.0028 17.5 0.2 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY88253.1 - 4.7e-05 23.0 0.6 0.24 11.2 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY88253.1 - 0.00015 21.7 0.0 0.42 10.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran_Xtn PF12848.7 ORY88253.1 - 0.00016 21.6 2.1 0.00016 21.6 2.1 2.4 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 ORY88253.1 - 0.00027 21.4 0.1 0.088 13.2 0.0 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ORY88253.1 - 0.0012 18.9 1.0 1 9.4 0.2 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY88253.1 - 0.0015 18.3 3.1 0.98 9.1 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_7 PF12775.7 ORY88253.1 - 0.0029 17.1 0.2 2.2 7.7 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 ORY88253.1 - 0.003 18.1 13.9 0.51 10.8 4.2 3.7 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 ORY88253.1 - 0.0043 17.0 0.0 0.082 12.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.25 ORY88253.1 - 0.0059 16.3 0.2 0.14 11.8 0.1 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 ORY88253.1 - 0.015 15.6 1.4 2.7 8.2 0.1 3.1 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 ORY88253.1 - 0.017 15.3 0.2 0.37 10.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORY88253.1 - 0.021 15.2 0.1 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 ORY88253.1 - 0.2 11.9 0.4 16 5.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ORY88253.1 - 0.24 10.5 1.6 1.5 8.0 0.2 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 ORY88253.1 - 0.64 10.0 4.0 26 4.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY88253.1 - 1.3 9.3 3.8 5.4 7.3 0.1 3.3 3 2 0 3 3 3 0 AAA domain F-box-like PF12937.7 ORY88254.1 - 2.7e-10 40.0 0.2 2.7e-10 40.0 0.2 2.5 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 ORY88254.1 - 3.9e-05 23.9 7.0 0.35 11.3 0.1 6.3 6 1 2 8 8 8 2 Leucine Rich repeats (2 copies) RE_XcyI PF09571.10 ORY88254.1 - 0.12 11.6 0.0 0.43 9.8 0.0 1.8 2 0 0 2 2 2 0 XcyI restriction endonuclease FA_desaturase PF00487.24 ORY88255.1 - 1.1e-22 81.1 23.0 2.7e-22 79.9 20.4 2.0 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 ORY88255.1 - 4.6e-20 70.8 1.1 8.3e-20 70.0 1.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Flavi_M PF01004.19 ORY88255.1 - 0.12 12.1 0.2 0.27 11.0 0.2 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M His_Me_b4a2 PF18275.1 ORY88256.1 - 2.8 8.1 6.9 3.6 7.7 1.0 2.4 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain Adaptin_N PF01602.20 ORY88257.1 - 1.4e-111 373.6 0.2 1.9e-111 373.2 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ORY88257.1 - 5.9e-19 68.4 0.9 5.9e-19 68.4 0.9 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORY88257.1 - 3.1e-08 33.8 0.6 0.00083 19.4 0.0 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 VHS PF00790.19 ORY88257.1 - 0.11 12.4 0.0 0.74 9.7 0.0 2.4 2 0 0 2 2 2 0 VHS domain Nucleoporin_FG PF13634.6 ORY88257.1 - 0.96 10.3 4.0 2.8 8.8 4.0 1.8 1 1 0 1 1 1 0 Nucleoporin FG repeat region Spc7 PF08317.11 ORY88258.1 - 0.017 14.0 8.9 0.021 13.7 8.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YkyA PF10368.9 ORY88258.1 - 0.034 13.8 4.2 0.049 13.3 4.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein MRP-S27 PF10037.9 ORY88258.1 - 0.054 12.4 6.3 0.069 12.0 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Occludin_ELL PF07303.13 ORY88258.1 - 0.12 13.1 6.5 0.13 13.0 4.6 2.0 1 1 0 2 2 2 0 Occludin homology domain Flagellin_N PF00669.20 ORY88258.1 - 0.2 11.8 7.4 0.95 9.6 2.9 2.4 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4407 PF14362.6 ORY88258.1 - 0.35 10.2 12.4 0.24 10.7 4.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 ORY88258.1 - 0.6 10.5 11.4 0.96 9.9 11.4 1.3 1 0 0 1 1 1 0 Fez1 FUSC PF04632.12 ORY88258.1 - 0.8 8.2 10.4 1.1 7.7 10.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.14 ORY88258.1 - 1.2 9.5 7.4 1.6 9.1 7.4 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 ORY88258.1 - 4.6 7.7 12.1 2.2 8.7 8.5 2.0 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 ORY88258.1 - 6.1 7.1 8.9 2 8.7 1.7 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DotU PF09850.9 ORY88259.1 - 0.0035 17.1 1.4 0.0044 16.7 0.9 1.5 1 1 0 1 1 1 1 Type VI secretion system protein DotU MCD_N PF17408.2 ORY88259.1 - 0.062 13.4 2.3 0.1 12.8 0.4 2.2 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain SbcD_C PF12320.8 ORY88259.1 - 0.69 10.3 7.0 0.78 10.1 4.4 2.2 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain NuA4 PF09340.10 ORY88260.1 - 1.2e-20 73.2 1.1 1.5e-20 72.9 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Macoilin PF09726.9 ORY88260.1 - 1.9 6.9 7.3 0.053 12.1 0.8 1.6 2 0 0 2 2 2 0 Macoilin family ATPase_2 PF01637.18 ORY88261.1 - 1e-12 48.5 0.0 2.6e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY88261.1 - 0.0001 22.6 0.0 0.034 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY88261.1 - 0.0002 21.8 3.8 0.00029 21.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.29 ORY88261.1 - 0.00059 20.3 0.0 0.76 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.9 ORY88261.1 - 0.0059 15.4 0.0 0.009 14.8 0.0 1.3 1 0 0 1 1 1 1 RNA12 protein AAA_14 PF13173.6 ORY88261.1 - 0.014 15.4 0.0 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.22 ORY88263.1 - 5.1e-17 61.4 0.0 1.8e-07 30.9 0.0 3.9 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MATH PF00917.26 ORY88265.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 MATH domain CRIM PF16978.5 ORY88266.1 - 2.5e-45 154.1 0.1 7.1e-45 152.6 0.0 1.8 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 ORY88266.1 - 2.8e-28 98.4 0.0 5.5e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 ORY88266.1 - 2.1e-05 24.7 0.0 5.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain RA PF00788.23 ORY88266.1 - 0.0019 18.8 0.0 0.041 14.5 0.0 2.4 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain RBD PF02196.15 ORY88266.1 - 0.0074 16.3 0.1 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 Raf-like Ras-binding domain FERM_N PF09379.10 ORY88266.1 - 0.1 12.6 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 FERM N-terminal domain MFS_1 PF07690.16 ORY88267.1 - 4e-20 72.0 34.3 4e-20 72.0 34.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.20 ORY88268.1 - 3.3e-13 50.0 0.0 6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY88268.1 - 9.6e-12 45.7 0.0 1.7e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Pyr_redox_2 PF07992.14 ORY88269.1 - 4.3e-10 39.3 0.0 5.7e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 ORY88269.1 - 1.1e-09 37.2 0.7 0.00029 19.4 0.0 2.7 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY88269.1 - 2.9e-08 33.4 0.3 4.5e-07 29.4 0.1 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY88269.1 - 5.4e-07 29.7 0.7 2.7e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY88269.1 - 5.5e-06 26.5 0.1 2.1e-05 24.6 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY88269.1 - 6.6e-05 22.2 0.3 0.0034 16.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORY88269.1 - 0.00064 19.0 0.7 0.16 11.2 0.1 3.1 3 0 0 3 3 3 1 Thi4 family Trp_halogenase PF04820.14 ORY88269.1 - 0.00095 18.1 0.1 1.2 7.9 0.2 2.3 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 ORY88269.1 - 0.0014 18.3 2.1 0.0043 16.7 2.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase IlvN PF07991.12 ORY88269.1 - 0.11 12.1 0.2 18 4.8 0.1 2.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 ORY88269.1 - 0.17 11.1 0.3 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 ORY88269.1 - 0.24 10.5 0.1 5.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A CHCH PF06747.13 ORY88270.1 - 1.7e-05 24.8 6.0 2.4e-05 24.3 6.0 1.2 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 ORY88270.1 - 0.0044 16.7 0.8 0.0055 16.4 0.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) GCK PF07802.11 ORY88270.1 - 0.03 14.7 1.7 0.045 14.2 1.7 1.2 1 0 0 1 1 1 0 GCK domain COX17 PF05051.13 ORY88270.1 - 0.035 14.5 4.5 0.19 12.1 0.5 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 ORY88270.1 - 0.041 14.2 4.7 0.14 12.5 2.5 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 ORY88270.1 - 0.051 13.6 2.8 0.072 13.1 2.8 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 ORY88270.1 - 0.071 13.1 3.9 0.11 12.5 3.9 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PBP PF01161.20 ORY88272.1 - 3.2e-15 56.6 0.0 4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_M50 PF02163.22 ORY88273.1 - 7.1e-14 51.7 0.0 1.2e-08 34.5 0.0 3.1 2 1 0 2 2 2 2 Peptidase family M50 PDZ_2 PF13180.6 ORY88273.1 - 0.11 12.8 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain zf-rbx1 PF12678.7 ORY88274.1 - 3.8e-09 36.7 0.3 4.9e-09 36.4 0.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY88274.1 - 8.5e-09 35.6 0.2 1.3e-08 35.1 0.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY88274.1 - 2.5e-07 30.4 0.2 3.6e-07 29.9 0.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY88274.1 - 0.00012 22.1 0.3 0.00018 21.5 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 ORY88274.1 - 0.00026 20.7 0.1 0.00041 20.0 0.1 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY88274.1 - 0.00048 19.9 0.1 0.00061 19.6 0.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY88274.1 - 0.0034 17.4 0.1 0.0049 16.9 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORY88274.1 - 0.0072 15.9 1.0 0.0099 15.5 1.0 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 ORY88274.1 - 0.0083 16.1 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 ORY88274.1 - 0.018 15.2 0.3 0.028 14.6 0.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORY88274.1 - 0.025 14.4 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 ORY88274.1 - 0.072 13.4 0.8 0.1 13.0 0.8 1.2 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 ORY88274.1 - 0.077 12.8 0.2 0.11 12.3 0.2 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GCP_N_terminal PF17681.1 ORY88276.1 - 5.3e-66 223.3 0.0 1.1e-65 222.3 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY88276.1 - 3.3e-62 210.7 8.3 5.9e-62 209.9 8.3 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal PBP1_TM PF14812.6 ORY88276.1 - 0.16 12.3 3.3 0.67 10.4 3.3 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AMP-binding PF00501.28 ORY88277.1 - 4.8e-80 269.2 0.1 6.3e-80 268.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY88277.1 - 1.8e-13 51.3 1.5 3.6e-13 50.3 0.6 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain COesterase PF00135.28 ORY88278.1 - 7e-99 332.0 0.0 1e-98 331.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 ORY88278.1 - 0.0032 17.0 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORY88278.1 - 0.048 13.5 0.0 0.18 11.6 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold WH1 PF00568.23 ORY88279.1 - 8.9e-15 54.6 0.0 1.4e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.28 ORY88279.1 - 7.3e-11 42.3 0.1 1.4e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain EF-hand_1 PF00036.32 ORY88280.1 - 2.3e-43 142.5 8.9 4.7e-10 38.3 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY88280.1 - 2e-36 124.3 1.3 3.1e-18 66.0 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 ORY88280.1 - 9.1e-33 111.9 8.5 1.3e-13 50.5 0.2 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 ORY88280.1 - 4.5e-32 107.2 5.7 1.1e-09 37.4 0.0 4.6 4 2 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 ORY88280.1 - 2.2e-28 96.5 5.8 2e-06 27.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORY88280.1 - 4.9e-15 55.6 0.1 1.2e-08 35.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORY88280.1 - 4.7e-11 42.6 0.4 4.2e-05 23.5 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY88280.1 - 1.3e-09 38.4 0.0 0.00024 21.4 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 ORY88280.1 - 5.5e-06 26.3 4.0 0.1 12.7 0.0 3.6 4 1 1 5 5 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 ORY88280.1 - 9.1e-06 25.7 0.9 3.7e-05 23.7 0.1 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 ORY88280.1 - 3.3e-05 24.0 3.4 0.031 14.5 0.3 2.9 1 1 2 3 3 3 2 Dockerin type I domain Caleosin PF05042.13 ORY88280.1 - 0.0005 20.0 0.5 0.53 10.2 0.0 3.3 1 1 2 3 3 3 1 Caleosin related protein EF-hand_11 PF08976.11 ORY88280.1 - 0.00063 20.6 0.0 0.27 12.1 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain DUF1103 PF06513.11 ORY88280.1 - 0.00074 19.2 1.2 0.00081 19.1 1.2 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) DUF4497 PF14924.6 ORY88280.1 - 0.0023 18.4 0.0 1.3 9.5 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) TerB PF05099.13 ORY88280.1 - 0.0036 17.3 0.6 0.67 9.9 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB Poly_export PF02563.16 ORY88280.1 - 0.004 17.3 0.1 1.2 9.4 0.0 3.0 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein DUF3349 PF11829.8 ORY88280.1 - 0.0042 17.8 0.2 6.9 7.5 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF5580 PF17743.1 ORY88280.1 - 0.021 13.4 0.0 0.024 13.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Fe_hyd_lg_C PF02906.14 ORY88280.1 - 0.021 14.5 0.4 0.049 13.3 0.4 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain MotA_activ PF09114.10 ORY88280.1 - 0.021 14.9 0.3 0.32 11.2 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RNA_pol_Rpb4 PF03874.16 ORY88280.1 - 0.025 14.9 0.3 13 6.1 0.0 2.7 2 1 1 3 3 3 0 RNA polymerase Rpb4 DUF1811 PF08838.10 ORY88280.1 - 0.036 14.3 0.1 7.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) SurA_N_2 PF13623.6 ORY88280.1 - 0.037 13.9 0.9 3.8 7.4 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 ORY88280.1 - 0.081 12.1 0.2 5 6.2 0.1 2.4 1 1 1 2 2 2 0 Cache domain Peptidase_M24 PF00557.24 ORY88280.1 - 0.082 12.6 0.3 2.9 7.5 0.1 2.3 1 1 0 2 2 2 0 Metallopeptidase family M24 PheRS_DBD2 PF18554.1 ORY88280.1 - 0.13 12.3 0.0 19 5.3 0.0 2.5 2 0 0 2 2 2 0 PheRS DNA binding domain 2 UBA_6 PF18039.1 ORY88280.1 - 0.15 12.0 0.0 10 6.2 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain SapB_1 PF05184.15 ORY88280.1 - 0.17 11.9 0.2 27 4.9 0.0 3.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 PhzC-PhzF PF02567.16 ORY88281.1 - 1.9e-51 175.2 0.0 2.3e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein PhzC-PhzF PF02567.16 ORY88282.1 - 2.9e-32 112.3 0.0 3.7e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein FA_desaturase PF00487.24 ORY88283.1 - 3.2e-26 92.7 18.8 6.7e-26 91.6 18.8 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY88283.1 - 2e-06 27.8 0.0 4.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 3Beta_HSD PF01073.19 ORY88284.1 - 1.2e-16 60.6 0.0 1.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY88284.1 - 2.8e-13 49.9 0.0 8.6e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY88284.1 - 2e-09 37.6 0.1 3.5e-09 36.8 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY88284.1 - 1.7e-08 34.0 0.4 1.4e-07 30.9 0.4 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY88284.1 - 4.3e-07 29.4 0.2 1.2e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY88284.1 - 1.1e-05 25.2 0.7 2.4e-05 24.0 0.3 1.7 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY88284.1 - 1.3e-05 24.8 0.1 8.6e-05 22.1 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY88284.1 - 3.9e-05 23.2 1.0 0.00021 20.8 0.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY88284.1 - 0.0067 16.4 0.8 0.042 13.8 0.7 2.0 1 1 0 1 1 1 1 KR domain Ribosomal_L24e PF01246.20 ORY88285.1 - 1.7e-32 111.4 0.4 2.6e-32 110.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L24e Herpes_UL79 PF03049.14 ORY88285.1 - 0.15 11.7 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 UL79 family 3Beta_HSD PF01073.19 ORY88286.1 - 7.6e-17 61.2 0.0 1.1e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY88286.1 - 1.6e-13 50.7 0.0 5.5e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY88286.1 - 1.3e-09 38.2 0.1 2.5e-09 37.3 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY88286.1 - 1e-08 34.7 0.4 9.9e-08 31.5 0.4 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY88286.1 - 2.8e-07 30.0 0.2 8.9e-07 28.3 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY88286.1 - 7e-06 25.8 0.8 1.8e-05 24.4 0.3 1.8 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY88286.1 - 9e-06 25.3 0.3 8.7e-05 22.1 0.0 2.4 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY88286.1 - 2.4e-05 23.9 0.9 0.00016 21.2 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY88286.1 - 0.0048 16.8 0.7 0.031 14.2 0.7 2.0 1 1 0 1 1 1 1 KR domain TMEM171 PF15471.6 ORY88288.1 - 3.5 6.5 3.9 9.1 5.2 4.2 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 SPT_ssu-like PF11779.8 ORY88289.1 - 2.2e-10 40.0 4.6 3.3e-10 39.4 4.6 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Sigma70_r4_2 PF08281.12 ORY88291.1 - 0.016 14.9 0.6 0.028 14.1 0.1 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_ECF PF07638.11 ORY88291.1 - 0.018 14.9 0.2 0.037 13.9 0.0 1.5 1 1 1 2 2 2 0 ECF sigma factor HTH_IclR PF09339.10 ORY88291.1 - 0.029 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain RTP1_C1 PF10363.9 ORY88294.1 - 2.8e-36 124.1 1.2 2.5e-35 121.0 0.1 2.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 ORY88294.1 - 8.2e-05 22.2 0.7 0.00017 21.2 0.7 1.5 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_2 PF13646.6 ORY88294.1 - 0.001 19.4 1.4 2.1 8.8 0.1 3.6 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 ORY88294.1 - 0.013 15.7 0.1 83 3.9 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat Pap_E4 PF02711.14 ORY88294.1 - 0.49 11.4 5.4 1.4 10.0 5.4 1.7 1 0 0 1 1 1 0 E4 protein ER-remodelling PF14755.6 ORY88294.1 - 1.5 9.1 5.4 3.7 7.8 2.4 2.4 2 0 0 2 2 2 0 Intracellular membrane remodeller ISG65-75 PF11727.8 ORY88295.1 - 0.41 9.8 13.2 0.23 10.7 10.8 1.7 1 1 1 2 2 2 0 Invariant surface glycoprotein Bacillus_HBL PF05791.11 ORY88295.1 - 2.5 7.9 5.2 4.6 7.0 0.3 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 ORY88295.1 - 2.7 7.3 16.5 3.7 6.8 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box PF00646.33 ORY88296.1 - 8.4e-06 25.5 0.2 3e-05 23.8 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY88296.1 - 0.00015 21.6 0.2 0.00041 20.2 0.1 1.8 2 0 0 2 2 2 1 F-box-like TRAM_LAG1_CLN8 PF03798.16 ORY88299.1 - 4e-05 23.4 9.3 7.1e-05 22.6 9.3 1.4 1 0 0 1 1 1 1 TLC domain SURF2 PF05477.11 ORY88300.1 - 0.72 9.5 5.2 1.3 8.6 5.2 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CDC45 PF02724.14 ORY88300.1 - 5.5 5.2 10.2 8 4.6 10.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.9 ORY88301.1 - 0.075 12.6 15.2 0.17 11.4 15.2 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 ORY88301.1 - 2.7 6.4 4.9 3.1 6.3 4.9 1.1 1 0 0 1 1 1 0 Macoilin family Pmp3 PF01679.17 ORY88302.1 - 1.8e-22 79.2 10.6 2.3e-22 78.9 10.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RraB PF06877.11 ORY88303.1 - 0.16 12.7 0.0 4.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Regulator of ribonuclease activity B LSM PF01423.22 ORY88304.1 - 5.7e-15 54.7 0.0 7.6e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY88304.1 - 0.035 13.7 0.1 0.093 12.4 0.0 1.7 1 1 1 2 2 2 0 Hfq protein S1_2 PF13509.6 ORY88304.1 - 0.09 12.8 0.0 1.4 9.1 0.0 2.1 1 1 1 2 2 2 0 S1 domain F-box PF00646.33 ORY88307.1 - 0.049 13.5 1.0 0.11 12.4 1.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY88307.1 - 0.11 12.5 0.7 0.32 10.9 0.7 1.9 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.7 ORY88309.1 - 0.0032 17.3 0.4 0.01 15.7 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY88309.1 - 0.0055 16.5 1.2 0.037 13.9 0.1 2.8 2 0 0 2 2 2 1 F-box domain NAT PF04768.13 ORY88310.1 - 9.1e-47 158.9 0.1 1.6e-46 158.1 0.1 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 ORY88310.1 - 1.7e-30 105.9 0.0 4.2e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 ORY88310.1 - 5.1e-24 85.2 0.1 8.9e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Amino acid kinase family DUF2379 PF09543.10 ORY88310.1 - 0.16 12.2 1.9 0.73 10.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) Thaumatin PF00314.17 ORY88312.1 - 4.4e-55 186.6 13.5 7e-55 186.0 13.5 1.3 1 0 0 1 1 1 1 Thaumatin family 4HBT PF03061.22 ORY88312.1 - 0.00043 20.6 0.0 0.00076 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 ORY88312.1 - 0.005 17.3 0.0 0.0077 16.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ORY88312.1 - 0.064 12.5 0.2 0.093 12.0 0.2 1.1 1 0 0 1 1 1 0 Acyl-ACP thioesterase S1-P1_nuclease PF02265.16 ORY88313.1 - 3.3e-51 174.5 0.0 1.4e-42 146.2 0.1 2.0 2 0 0 2 2 2 2 S1/P1 Nuclease Thiolase_N PF00108.23 ORY88314.1 - 1.9e-86 289.6 3.0 2.9e-86 289.1 3.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY88314.1 - 3.7e-42 142.8 1.3 3.7e-42 142.8 1.3 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY88314.1 - 0.00013 21.6 3.3 0.00018 21.2 0.5 2.4 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY88314.1 - 0.26 11.2 4.5 5.6 6.9 0.1 3.5 2 1 1 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DPM2 PF07297.12 ORY88315.1 - 9.5e-31 105.9 0.3 1.1e-30 105.7 0.3 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 ORY88315.1 - 2.1e-06 27.6 0.6 2.3e-06 27.5 0.6 1.1 1 0 0 1 1 1 1 PIG-P Oberon_cc PF16312.5 ORY88316.1 - 0.087 12.8 2.2 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil region of Oberon Atg14 PF10186.9 ORY88317.1 - 7.3e-22 77.9 0.0 4e-21 75.4 0.0 1.9 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 ORY88317.1 - 0.14 9.6 4.8 0.2 9.1 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MFS_1 PF07690.16 ORY88318.1 - 1.4e-39 136.1 20.1 1.4e-39 136.1 20.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY88318.1 - 2.5e-14 53.0 5.8 2.5e-14 53.0 5.8 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORY88318.1 - 2.1e-06 26.8 5.5 0.00075 18.5 0.4 2.6 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 ORY88318.1 - 0.0013 17.4 4.2 0.0013 17.4 4.2 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein OATP PF03137.20 ORY88318.1 - 0.0034 15.8 0.8 0.0072 14.7 0.4 1.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Cytochrom_B561 PF03188.16 ORY88319.1 - 6.5e-09 36.0 2.2 1.9e-08 34.6 2.2 1.8 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 ORY88319.1 - 5.9e-06 26.1 1.8 1.4e-05 24.8 1.8 1.6 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF4079 PF13301.6 ORY88319.1 - 0.00014 22.0 1.8 0.0092 16.1 0.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4079) COX15-CtaA PF02628.15 ORY88319.1 - 0.00075 18.7 6.3 0.0014 17.8 6.3 1.4 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DOMON PF03351.17 ORY88319.1 - 0.046 13.9 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 DOMON domain DUF3382 PF11862.8 ORY88319.1 - 0.5 10.7 7.8 2 8.8 1.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) DUF420 PF04238.12 ORY88319.1 - 3.1 8.1 7.9 6.1 7.1 1.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF420) Kin17_mid PF10357.9 ORY88320.1 - 1.4e-48 164.0 0.2 2e-48 163.5 0.2 1.2 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 ORY88320.1 - 0.0052 17.1 3.8 0.011 16.1 3.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY88320.1 - 0.036 14.4 2.8 0.071 13.4 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding F-box-like PF12937.7 ORY88321.1 - 2e-06 27.6 0.4 2e-06 27.6 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 ORY88322.1 - 0.0091 15.9 0.1 0.025 14.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.18 ORY88323.1 - 9.1e-12 44.9 6.7 1.7e-11 44.0 6.7 1.5 1 0 0 1 1 1 1 MYND finger Anp1 PF03452.14 ORY88325.1 - 1.4e-83 280.4 0.0 1.7e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Anp1 DUF1744 PF08490.12 ORY88326.1 - 2.3e-141 471.0 0.0 3.2e-141 470.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 ORY88326.1 - 1.8e-81 273.9 0.0 2.8e-81 273.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY88326.1 - 8.3e-12 44.5 0.0 1.5e-09 37.1 0.0 3.6 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 ORY88326.1 - 1.4e-09 38.0 0.1 4.4e-09 36.3 0.1 1.8 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 ORY88326.1 - 3.2e-05 24.0 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily DUF2841 PF11001.8 ORY88328.1 - 1.8e-34 118.4 0.6 4.1e-34 117.3 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF1168 PF06658.12 ORY88328.1 - 0.92 9.3 4.4 0.54 10.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) zf-MYND PF01753.18 ORY88329.1 - 3.4e-10 39.8 6.3 6.4e-10 39.0 6.3 1.5 1 0 0 1 1 1 1 MYND finger DUF35_N PF12172.8 ORY88329.1 - 4.9 7.1 9.1 2.9 7.9 1.3 2.9 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Dna2 PF08696.11 ORY88330.1 - 9.5e-51 172.5 0.0 1.6e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 ORY88330.1 - 1.5e-49 168.4 0.0 2.3e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY88330.1 - 1.1e-14 54.9 0.0 2.7e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY88330.1 - 1.6e-11 44.3 0.0 8.1e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY88330.1 - 2.4e-07 31.2 0.0 5.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 ORY88330.1 - 7e-07 29.4 0.3 1.7e-06 28.2 0.3 1.7 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 ORY88330.1 - 3.2e-05 24.1 1.9 0.024 14.7 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF83 AAA_16 PF13191.6 ORY88330.1 - 0.00051 20.5 0.0 0.0018 18.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 ORY88330.1 - 0.00072 19.2 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Viral_helicase1 PF01443.18 ORY88330.1 - 0.0025 17.6 0.1 0.17 11.6 0.0 2.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 ORY88330.1 - 0.005 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD-helicase PF00580.21 ORY88330.1 - 0.0054 16.3 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 ORY88330.1 - 0.0071 16.6 0.2 0.072 13.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 ORY88330.1 - 0.0077 16.3 0.4 0.021 14.9 0.4 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 ORY88330.1 - 0.011 15.3 0.1 0.024 14.3 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 ORY88330.1 - 0.025 14.6 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORY88330.1 - 0.028 13.5 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 ORY88330.1 - 0.037 13.2 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_33 PF13671.6 ORY88330.1 - 0.061 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 ORY88330.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase DUF853 PF05872.12 ORY88330.1 - 0.075 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA PF00004.29 ORY88330.1 - 0.076 13.4 0.1 0.22 12.0 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRM_5 PF13893.6 ORY88330.1 - 0.088 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_25 PF13481.6 ORY88330.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain F-box PF00646.33 ORY88331.1 - 2.5e-07 30.4 0.4 4.5e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY88331.1 - 1.1e-06 28.4 0.2 3e-06 27.0 0.1 1.7 2 0 0 2 2 2 1 F-box-like Thaumatin PF00314.17 ORY88332.1 - 7e-70 235.0 11.5 7.9e-70 234.8 11.5 1.0 1 0 0 1 1 1 1 Thaumatin family WD40 PF00400.32 ORY88334.1 - 1.1e-45 152.7 21.7 2.3e-08 34.6 0.1 8.1 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY88334.1 - 1.1e-16 60.9 0.0 0.0014 18.9 0.0 5.8 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY88334.1 - 5.6e-06 25.5 0.2 0.05 12.6 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY88334.1 - 6.7e-05 22.4 0.0 0.44 9.8 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 ORY88334.1 - 9.1e-05 22.2 2.6 0.00037 20.1 0.9 2.2 1 1 1 2 2 2 2 PQQ-like domain eIF2A PF08662.11 ORY88334.1 - 0.0016 18.3 0.2 1.6 8.5 0.0 3.0 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 ORY88334.1 - 0.0034 15.8 0.0 1.2 7.3 0.0 2.7 2 1 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz CBS PF00571.28 ORY88335.1 - 1.3e-09 38.3 0.0 6.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 CBS domain Phage_XkdX PF09693.10 ORY88335.1 - 0.055 13.5 0.1 5.1 7.2 0.0 2.7 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) Glyco_transf_22 PF03901.17 ORY88336.1 - 4.4e-46 158.0 14.2 5.5e-46 157.6 14.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 ORY88336.1 - 3.3 7.9 14.2 0.083 13.1 6.6 2.1 2 1 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Rad17 PF03215.15 ORY88337.1 - 2.2e-24 86.4 0.0 2.4e-23 83.1 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 ORY88337.1 - 0.024 14.9 0.0 0.094 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 ORY88337.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA C-terminal domain F-box-like PF12937.7 ORY88338.1 - 1.4e-05 24.9 0.8 3.1e-05 23.8 0.8 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 ORY88338.1 - 0.091 12.5 0.1 8 6.3 0.1 2.8 2 1 0 2 2 2 0 Leucine rich repeat F-box-like PF12937.7 ORY88339.1 - 0.00045 20.1 0.1 0.00095 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 ORY88340.1 - 0.0003 20.6 0.1 0.00064 19.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY88340.1 - 0.12 12.3 0.6 0.43 10.5 0.6 2.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY88341.1 - 0.00073 19.4 0.1 0.0015 18.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY88341.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 F-box domain HMw1_D2 PF18254.1 ORY88341.1 - 0.098 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 HMW1 domain 2 HTH_IclR PF09339.10 ORY88342.1 - 0.0069 16.2 0.4 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_29 PF13551.6 ORY88342.1 - 0.0084 16.1 1.0 0.037 14.1 0.1 2.5 2 0 0 2 2 2 1 Winged helix-turn helix Sigma70_ECF PF07638.11 ORY88342.1 - 0.018 15.0 0.5 0.13 12.1 0.0 2.5 2 1 1 3 3 3 0 ECF sigma factor Na_trans_assoc PF06512.13 ORY88342.1 - 0.068 13.4 2.6 0.11 12.7 2.6 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated DUF465 PF04325.13 ORY88342.1 - 9.1 6.4 9.7 2.3 8.3 1.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF465) GFO_IDH_MocA PF01408.22 ORY88343.1 - 1.9e-17 64.2 0.1 2.9e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Bin3 PF06859.12 ORY88344.1 - 1.8e-34 118.6 0.0 3e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 ORY88344.1 - 3.6e-12 46.3 0.0 2.4e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORY88344.1 - 2.3e-11 44.2 0.0 4.2e-08 33.8 0.0 2.6 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORY88344.1 - 5.2e-11 42.7 0.0 8.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY88344.1 - 5.7e-09 36.5 0.0 2.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 ORY88344.1 - 9.2e-08 31.8 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 ORY88344.1 - 4.9e-07 30.4 0.0 0.0058 17.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 ORY88344.1 - 1.5e-06 27.9 0.0 8.2e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 ORY88344.1 - 0.00017 21.6 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY88344.1 - 0.0003 20.6 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 ORY88344.1 - 0.00044 19.3 0.0 0.0009 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ORY88344.1 - 0.0016 17.8 0.0 0.053 12.8 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase ADH_zinc_N PF00107.26 ORY88344.1 - 0.0034 17.3 0.2 0.011 15.7 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_4 PF02390.17 ORY88344.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 ORY88344.1 - 0.024 14.4 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 ORY88344.1 - 0.036 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF43 PF01861.16 ORY88344.1 - 0.04 13.1 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_32 PF13679.6 ORY88344.1 - 0.12 12.4 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 ORY88344.1 - 0.13 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase F-box PF00646.33 ORY88345.1 - 6.1e-07 29.2 0.3 1.2e-06 28.2 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY88345.1 - 2.1e-05 24.3 0.5 0.00012 21.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY88346.1 - 0.00011 22.0 0.8 0.00041 20.2 0.5 2.2 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY88346.1 - 0.00059 19.7 0.5 0.0015 18.4 0.5 1.7 1 0 0 1 1 1 1 F-box-like VAD1-2 PF15310.6 ORY88346.1 - 0.18 11.7 0.6 0.21 11.4 0.6 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Adap_comp_sub PF00928.21 ORY88347.1 - 2.6e-46 158.1 0.0 3.6e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY88347.1 - 0.066 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Glyco_hydro_28 PF00295.17 ORY88348.1 - 2.5e-69 233.8 25.1 2.9e-69 233.6 25.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 F-box PF00646.33 ORY88349.1 - 5.7e-09 35.6 0.4 3.5e-08 33.1 0.5 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY88349.1 - 9.5e-07 28.6 0.1 2.8e-06 27.1 0.2 1.7 2 0 0 2 2 2 1 F-box-like PAP_assoc PF03828.19 ORY88350.1 - 5e-06 26.6 0.0 0.0017 18.5 0.0 3.0 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY88350.1 - 0.0001 22.6 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.11 ORY88350.1 - 0.0066 16.7 0.0 0.025 14.8 0.0 1.9 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain GvpG PF05120.12 ORY88350.1 - 0.12 12.4 1.2 0.48 10.5 1.2 2.0 1 0 0 1 1 1 0 Gas vesicle protein G LRR_4 PF12799.7 ORY88351.1 - 0.16 12.4 12.0 4 8.0 0.2 5.8 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Sad1_UNC PF07738.13 ORY88352.1 - 1.2e-27 96.6 0.0 1.8e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal NAM-associated PF14303.6 ORY88352.1 - 0.51 11.1 0.0 0.51 11.1 0.0 7.0 4 1 2 6 6 6 0 No apical meristem-associated C-terminal domain Utp14 PF04615.13 ORY88352.1 - 2.5 6.5 32.7 12 4.3 30.5 2.1 2 0 0 2 2 2 0 Utp14 protein F-box-like PF12937.7 ORY88353.1 - 2.5e-06 27.2 0.4 5e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 ORY88353.1 - 0.28 11.0 4.3 4.7 7.1 0.0 3.6 5 0 0 5 5 5 0 Leucine rich repeat FAM193_C PF15914.5 ORY88353.1 - 0.28 10.9 3.3 0.65 9.8 3.3 1.5 1 0 0 1 1 1 0 FAM193 family C-terminal F-box PF00646.33 ORY88354.1 - 0.0018 18.1 0.2 0.0043 16.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY88354.1 - 0.0022 17.8 0.2 0.0022 17.8 0.2 1.7 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 ORY88354.1 - 0.012 15.4 0.1 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 F-box Glyco_hydro_28 PF00295.17 ORY88355.1 - 4.4e-69 233.0 22.2 5.5e-69 232.7 22.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pyridoxal_deC PF00282.19 ORY88356.1 - 6.9e-62 209.3 0.0 9.4e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY88356.1 - 1.8e-05 23.9 0.0 2.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V HEAT PF02985.22 ORY88358.1 - 2.7e-07 30.3 2.8 0.33 11.3 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 ORY88358.1 - 8.4e-07 29.3 12.5 9.9e-05 22.7 0.1 6.3 4 3 2 7 7 7 1 HEAT repeats HEAT_EZ PF13513.6 ORY88358.1 - 9.2e-05 22.9 1.1 0.29 11.7 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat DLP_helical PF18709.1 ORY88358.1 - 0.00029 20.1 0.9 0.0006 19.1 0.9 1.4 1 0 0 1 1 1 1 Dynamin-like helical domain Cnd1 PF12717.7 ORY88358.1 - 0.0065 16.5 6.4 0.3 11.1 0.2 5.3 5 1 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY88358.1 - 0.011 16.3 0.2 1.1 9.9 0.0 4.1 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RsbRD_N PF14361.6 ORY88358.1 - 0.012 16.3 1.9 0.14 12.9 0.0 3.5 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain rRNA_proc-arch PF13234.6 ORY88358.1 - 0.13 12.1 0.8 0.59 10.0 0.2 2.1 2 0 0 2 2 2 0 rRNA-processing arch domain DUF4600 PF15372.6 ORY88358.1 - 0.17 12.3 3.6 0.37 11.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) APG6_N PF17675.1 ORY88358.1 - 0.54 10.8 4.0 3.1 8.3 0.4 2.9 2 0 0 2 2 2 0 Apg6 coiled-coil region NARP1 PF12569.8 ORY88359.1 - 1.9e-165 551.7 11.3 1.9e-165 551.7 11.3 1.8 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 ORY88359.1 - 1.6e-11 44.5 15.8 3 8.4 0.0 9.5 8 2 1 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY88359.1 - 7.6e-11 41.3 13.4 1.2e-05 25.0 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY88359.1 - 2.5e-10 40.3 21.3 0.027 15.3 0.0 10.9 9 2 3 12 12 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY88359.1 - 1.4e-08 35.3 11.4 1.5 9.5 0.0 8.4 8 2 1 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY88359.1 - 2.5e-07 30.6 0.1 8.9 6.9 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY88359.1 - 1.4e-06 28.4 5.4 2.9 8.2 0.3 5.5 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 ORY88359.1 - 1.6e-06 27.8 1.0 0.0013 18.8 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY88359.1 - 2.8e-06 26.9 0.0 0.00048 19.8 0.0 3.5 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.28 ORY88359.1 - 4.2e-06 26.3 5.8 0.00013 21.6 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY88359.1 - 4.5e-06 26.9 9.5 0.84 10.4 0.0 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY88359.1 - 9.9e-06 25.6 5.7 0.1 12.7 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY88359.1 - 1.3e-05 24.5 12.5 0.0039 16.4 1.3 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 ORY88359.1 - 0.0011 19.0 4.2 1.1 9.4 0.2 4.0 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 ORY88359.1 - 0.0013 18.6 0.2 2.6 8.3 0.0 4.4 3 0 0 3 3 2 1 Tetratricopeptide repeat LANC_like PF05147.13 ORY88359.1 - 0.0091 14.6 0.1 0.023 13.3 0.0 1.6 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein TPR_12 PF13424.6 ORY88359.1 - 0.011 16.1 0.4 0.011 16.1 0.4 6.8 6 3 1 7 7 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORY88359.1 - 0.041 13.5 0.5 2.1 8.0 0.1 2.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) U79_P34 PF03064.16 ORY88359.1 - 0.89 8.9 6.6 1.7 8.0 6.6 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GRDP-like PF07173.12 ORY88360.1 - 7.3e-10 39.7 0.0 1.7e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like Zn-ribbon_8 PF09723.10 ORY88360.1 - 0.024 14.7 0.6 0.37 11.0 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Anti-TRAP PF15777.5 ORY88360.1 - 0.93 9.5 2.4 2.4 8.2 2.4 1.6 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein DNA_pol_E_B PF04042.16 ORY88361.1 - 7.3e-50 169.2 0.1 1e-49 168.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos PF00149.28 ORY88361.1 - 0.015 15.8 0.0 0.034 14.7 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase DNA_pol_D_N PF18018.1 ORY88361.1 - 0.22 11.6 0.1 0.43 10.7 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain MFS_1 PF07690.16 ORY88374.1 - 1.7e-35 122.6 12.7 2.1e-35 122.3 12.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY88374.1 - 4.5e-09 35.7 11.5 6.7e-09 35.1 11.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY88374.1 - 1e-06 28.3 1.8 1.3e-06 28.0 1.8 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ORY88374.1 - 7.4e-06 24.5 0.1 1.2e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF3096 PF11295.8 ORY88374.1 - 0.0067 16.1 0.6 0.0067 16.1 0.6 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3096) DUF4231 PF14015.6 ORY88374.1 - 0.097 13.1 2.6 8.4 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Rhodanese PF00581.20 ORY88375.1 - 3.8e-06 27.4 0.0 0.00097 19.6 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain zf-AN1 PF01428.16 ORY88377.1 - 5.8e-21 74.4 22.8 5.2e-12 45.7 5.2 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Translin PF01997.16 ORY88378.1 - 1.8e-46 158.8 0.0 2.1e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Translin family RPN13_C PF16550.5 ORY88378.1 - 0.00021 21.4 0.4 0.0005 20.2 0.1 1.8 2 0 0 2 2 2 1 UCH-binding domain AAA_21 PF13304.6 ORY88378.1 - 0.046 13.5 0.2 0.06 13.2 0.2 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2156 PF09924.9 ORY88379.1 - 3.9e-16 58.9 0.0 4.9e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Acetyltransf_10 PF13673.7 ORY88379.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY88379.1 - 0.036 14.3 0.2 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 ORY88379.1 - 0.099 12.8 0.1 0.34 11.1 0.1 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Fer4_12 PF13353.6 ORY88379.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Abhydrolase_3 PF07859.13 ORY88380.1 - 8.9e-19 68.2 0.0 1.2e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY88380.1 - 0.00044 19.2 0.0 0.0025 16.8 0.0 1.8 2 0 0 2 2 2 1 Steryl acetyl hydrolase BatA PF07584.11 ORY88380.1 - 0.0029 18.0 1.4 0.009 16.4 1.4 1.9 1 0 0 1 1 1 1 Aerotolerance regulator N-terminal His_Phos_1 PF00300.22 ORY88381.1 - 1.7e-15 57.2 1.3 5.1e-15 55.7 1.3 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_hydro_2_C PF02836.17 ORY88384.1 - 0.0012 18.0 0.2 0.0025 17.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF936 PF06075.12 ORY88384.1 - 0.13 11.1 19.6 0.18 10.7 19.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Utp14 PF04615.13 ORY88384.1 - 0.35 9.4 17.6 0.42 9.1 17.6 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 ORY88384.1 - 3.5 6.1 22.9 4.8 5.6 22.9 1.1 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 ORY88384.1 - 5.4 5.9 14.1 8.6 5.3 14.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 DDHD PF02862.17 ORY88384.1 - 6.7 6.8 15.2 29 4.7 15.2 1.9 1 1 0 1 1 1 0 DDHD domain Transp_cyt_pur PF02133.15 ORY88385.1 - 3e-85 286.6 38.5 1.2e-84 284.6 38.5 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 ORY88386.1 - 2.5e-42 145.1 38.5 2.5e-42 145.1 38.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY88386.1 - 2e-06 26.5 2.9 2e-06 26.5 2.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ORY88386.1 - 0.00015 21.2 3.7 0.00015 21.2 3.7 2.8 3 1 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB OAD_gamma PF04277.13 ORY88386.1 - 0.91 10.2 6.3 4 8.1 1.4 3.2 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain PS_Dcarbxylase PF02666.15 ORY88387.1 - 2.5e-42 144.7 0.0 4.9e-41 140.5 0.0 2.1 2 0 0 2 2 2 2 Phosphatidylserine decarboxylase Pkinase PF00069.25 ORY88388.1 - 1.8e-32 112.8 0.0 2.9e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88388.1 - 3.8e-10 39.5 0.0 6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY88388.1 - 0.00027 20.9 0.0 0.00065 19.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY88388.1 - 0.0043 16.4 0.0 0.007 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY88388.1 - 0.019 13.7 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 ORY88388.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RNA_pol_Rpc82 PF05645.13 ORY88388.1 - 0.45 10.2 1.6 0.41 10.4 0.2 1.5 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 Zn_clus PF00172.18 ORY88389.1 - 5.8e-05 23.1 3.8 5.8e-05 23.1 3.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.26 ORY88390.1 - 7e-18 65.2 0.5 1.7e-17 63.9 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY88390.1 - 1.7e-15 57.1 0.0 1.3e-14 54.3 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY88390.1 - 3.1e-13 49.5 0.9 1.1e-12 47.8 0.9 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PHY PF00360.20 ORY88390.1 - 1.6e-09 37.3 0.0 7e-08 32.0 0.0 2.6 1 1 0 1 1 1 1 Phytochrome region PAS_2 PF08446.11 ORY88390.1 - 6.2e-07 30.1 0.0 5.1e-05 23.9 0.0 3.0 2 0 0 2 2 2 1 PAS fold GAF PF01590.26 ORY88390.1 - 0.00012 22.7 0.1 0.0005 20.7 0.1 2.1 2 0 0 2 2 2 1 GAF domain HATPase_c_3 PF13589.6 ORY88390.1 - 0.0056 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CoaE PF01121.20 ORY88391.1 - 9.4e-57 191.6 0.0 1.2e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 ORY88391.1 - 2.2e-05 25.0 0.0 5.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY88391.1 - 0.058 13.6 0.0 0.99 9.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 ORY88392.1 - 1.4e-209 696.5 0.0 1.9e-209 696.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 ORY88392.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain F5_F8_type_C PF00754.25 ORY88393.1 - 7.3e-14 52.0 13.9 0.0012 18.9 0.2 4.9 4 0 0 4 4 4 4 F5/8 type C domain PIG-L PF02585.17 ORY88393.1 - 2.3e-10 41.2 0.0 5.2e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Ecl1 PF12855.7 ORY88393.1 - 0.97 10.6 72.4 5.2 8.2 18.2 3.8 3 0 0 3 3 3 0 ECL1/2/3 zinc binding proteins UPF0242 PF06785.11 ORY88394.1 - 0.00014 22.0 10.3 0.00014 22.0 10.3 4.0 1 1 3 4 4 4 1 Uncharacterised protein family (UPF0242) N-terminus Csm2_III-A PF03750.13 ORY88394.1 - 2.8 8.8 11.2 9 7.2 1.1 3.0 2 2 0 2 2 2 0 Csm2 Type III-A Spc7 PF08317.11 ORY88394.1 - 3.3 6.5 38.6 4.3 6.1 7.5 3.6 1 1 1 3 3 3 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 ORY88394.1 - 5.4 7.1 6.0 9.6 6.3 0.2 3.2 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 ORY88394.1 - 5.5 7.6 28.9 3.5 8.2 3.5 4.7 1 1 3 4 4 4 0 Syntaxin 6, N-terminal HMMR_N PF15905.5 ORY88394.1 - 6.2 6.2 39.8 0.022 14.3 13.4 2.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3292 PF11696.8 ORY88395.1 - 4.3e-100 336.0 0.0 4.4e-99 332.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.10 ORY88395.1 - 0.034 13.9 0.0 0.29 10.9 0.0 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Sterol_MT_C PF08498.10 ORY88396.1 - 1.4e-29 102.2 0.3 2.3e-29 101.5 0.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 ORY88396.1 - 4.6e-19 68.9 0.1 1e-18 67.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY88396.1 - 1.6e-18 66.9 0.0 2.8e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY88396.1 - 3e-17 63.1 0.0 6.4e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY88396.1 - 3.2e-17 62.7 0.1 4.8e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORY88396.1 - 1.2e-13 51.2 0.0 2.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY88396.1 - 1e-12 48.6 0.0 2.6e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY88396.1 - 5.8e-10 38.9 0.0 9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 ORY88396.1 - 0.00038 20.1 0.1 0.00067 19.3 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.6 ORY88396.1 - 0.0015 19.5 0.0 0.0052 17.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 ORY88396.1 - 0.0018 18.1 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HRM PF02793.22 ORY88396.1 - 0.0022 18.2 1.3 0.007 16.6 1.3 1.8 1 0 0 1 1 1 1 Hormone receptor domain MTS PF05175.14 ORY88396.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 ORY88396.1 - 0.0038 16.4 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_2 PF00891.18 ORY88396.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF5087 PF17006.5 ORY88396.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) MetW PF07021.12 ORY88396.1 - 0.045 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.18 ORY88396.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.16 ORY88396.1 - 0.13 12.0 0.2 0.31 10.8 0.1 1.6 2 0 0 2 2 2 0 Met-10+ like-protein DUF1471 PF07338.13 ORY88397.1 - 0.054 13.5 0.8 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) Ricin_B_lectin PF00652.22 ORY88397.1 - 0.055 13.7 2.9 1 9.6 0.7 2.6 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ORY88397.1 - 0.077 13.7 6.0 2.1 9.1 0.0 3.4 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like AMPK1_CBM PF16561.5 ORY88399.1 - 1e-18 67.3 0.1 1.8e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 ORY88399.1 - 0.0032 17.8 0.2 0.0071 16.7 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 ORY88399.1 - 0.017 15.7 0.3 0.041 14.5 0.3 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Ribonuclease_T2 PF00445.18 ORY88401.1 - 9.8e-31 107.4 0.0 1.4e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Peptidase_S9 PF00326.21 ORY88402.1 - 4.8e-25 88.3 0.0 7.7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY88402.1 - 4.3e-08 33.1 1.6 5.1e-05 23.0 0.1 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY88402.1 - 3.5e-07 29.7 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 ORY88402.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tannase PF07519.11 ORY88402.1 - 0.011 14.6 0.0 0.067 12.1 0.0 1.9 2 0 0 2 2 2 0 Tannase and feruloyl esterase PhoPQ_related PF10142.9 ORY88402.1 - 0.03 13.0 0.0 0.044 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.11 ORY88402.1 - 0.21 11.5 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ThrE PF06738.12 ORY88403.1 - 8.7e-49 166.1 2.8 8.7e-49 166.1 2.8 2.1 2 0 0 2 2 2 1 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY88403.1 - 4.2e-09 36.6 7.1 4.2e-09 36.6 7.1 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE CDC45 PF02724.14 ORY88403.1 - 1.9 6.7 3.5 3.1 6.0 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein ThrE PF06738.12 ORY88404.1 - 5.7e-49 166.6 3.3 5.7e-49 166.6 3.3 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY88404.1 - 2.9e-09 37.1 3.5 2.9e-09 37.1 3.5 2.6 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE Transp_cyt_pur PF02133.15 ORY88406.1 - 1.2e-81 274.8 37.4 1.4e-81 274.6 37.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 ORY88407.1 - 1.9e-42 145.5 25.8 1.9e-42 145.5 25.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY88407.1 - 1.8e-07 30.0 4.7 2.6e-07 29.5 4.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY88407.1 - 6.2e-05 21.6 10.9 0.0002 19.9 6.0 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 ORY88407.1 - 0.00026 20.0 3.6 0.00026 20.0 3.6 2.3 2 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 ORY88407.1 - 1.4 7.1 8.8 0.033 12.5 0.7 2.4 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_3 PF07859.13 ORY88408.1 - 1.6e-14 54.2 0.0 1.1e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY88408.1 - 2.6e-10 40.1 0.0 4.2e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY88408.1 - 0.0015 17.9 0.0 0.074 12.3 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 COesterase PF00135.28 ORY88408.1 - 0.02 13.8 0.0 0.071 12.0 0.0 1.8 1 1 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.16 ORY88408.1 - 0.028 14.2 0.1 0.11 12.3 0.0 1.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF829 PF05705.14 ORY88408.1 - 0.048 13.6 0.0 0.075 12.9 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_4 PF08386.10 ORY88408.1 - 0.07 13.2 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Chlorophyllase2 PF12740.7 ORY88408.1 - 0.073 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 ORY88408.1 - 0.12 12.0 1.0 8.4 6.0 1.0 2.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Amidase PF01425.21 ORY88409.1 - 1.6e-93 314.1 0.0 2.1e-93 313.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Fungal_trans PF04082.18 ORY88410.1 - 4.8e-12 45.5 0.0 1.2e-11 44.1 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY88410.1 - 0.00075 19.6 6.1 0.0012 18.9 6.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.11 ORY88410.1 - 0.9 9.6 2.5 2 8.4 2.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 ORY88410.1 - 2.4 7.6 6.1 4.6 6.6 6.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Polysacc_deac_1 PF01522.21 ORY88411.1 - 5e-07 29.7 0.0 8.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase WVELL PF14043.6 ORY88411.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 WVELL protein SEN1_N PF12726.7 ORY88412.1 - 8.2e-145 483.9 0.2 1.2e-144 483.4 0.2 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 ORY88412.1 - 1.5e-71 241.3 0.0 1.5e-71 241.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 ORY88412.1 - 7.1e-59 198.8 0.0 1.3e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY88412.1 - 1.4e-08 34.7 1.5 7.9e-06 25.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 ORY88412.1 - 5.3e-08 33.3 0.0 1.9e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY88412.1 - 5.8e-05 22.9 0.0 0.088 12.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 ORY88412.1 - 0.063 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 ORY88412.1 - 0.16 11.8 0.0 0.46 10.4 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 ORY88412.1 - 0.17 11.9 0.0 0.55 10.2 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TMF_TATA_bd PF12325.8 ORY88412.1 - 8.8 6.6 9.4 0.41 10.9 1.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Arylesterase PF01731.20 ORY88413.1 - 0.0002 21.5 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 1 Arylesterase SGL PF08450.12 ORY88413.1 - 0.0014 18.2 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ORY88413.1 - 0.035 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Strictosidine synthase Ribosomal_L1 PF00687.21 ORY88414.1 - 8.7e-46 156.2 1.2 1.4e-45 155.6 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3697 PF12478.8 ORY88414.1 - 0.038 14.1 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-associated protein 2 Pro_CA PF00484.19 ORY88415.1 - 5.4e-37 127.5 0.1 2e-36 125.6 0.1 1.8 1 1 0 1 1 1 1 Carbonic anhydrase Gp_dh_C PF02800.20 ORY88416.1 - 3.2e-48 163.3 0.0 4.4e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORY88416.1 - 1.4e-30 105.6 0.0 3.1e-30 104.5 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain AAA_16 PF13191.6 ORY88417.1 - 0.021 15.2 0.5 0.043 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain zf-like PF04071.12 ORY88417.1 - 0.064 13.2 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Cysteine-rich small domain AAA_5 PF07728.14 ORY88417.1 - 0.14 12.2 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Cellulase PF00150.18 ORY88418.1 - 1.1e-08 34.8 0.1 2.4e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) T2SSM PF04612.12 ORY88418.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M DUF4131 PF13567.6 ORY88418.1 - 0.071 12.8 0.2 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pilin_N PF07790.11 ORY88418.1 - 0.26 12.3 2.2 0.52 11.3 2.2 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Rax2 PF12768.7 ORY88419.1 - 0.0036 16.8 0.1 0.0047 16.4 0.1 1.5 1 1 0 1 1 1 1 Cortical protein marker for cell polarity EphA2_TM PF14575.6 ORY88419.1 - 0.12 13.2 0.0 0.21 12.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Stevor PF17410.2 ORY88419.1 - 0.23 11.0 0.1 0.39 10.2 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame VSP PF03302.13 ORY88419.1 - 10 4.9 6.4 0.36 9.6 0.7 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein DUF2650 PF10853.8 ORY88421.1 - 0.67 9.7 3.3 1.4 8.7 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) CAP_N PF01213.19 ORY88421.1 - 5.5 6.4 10.3 9.3 5.6 10.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aldedh PF00171.22 ORY88424.1 - 2e-130 435.4 0.2 2.4e-130 435.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY88424.1 - 0.0029 16.7 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 ORY88424.1 - 0.0083 15.6 0.0 0.068 12.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) F-box-like PF12937.7 ORY88425.1 - 0.013 15.4 0.2 0.033 14.1 0.2 1.7 1 0 0 1 1 1 0 F-box-like Methyltransf_32 PF13679.6 ORY88426.1 - 1.1e-16 61.2 0.0 1.6e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF5321 PF17254.2 ORY88426.1 - 0.22 10.9 2.6 0.4 10.1 2.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5321) SPOR PF05036.13 ORY88427.1 - 0.2 12.1 0.2 0.5 10.8 0.2 1.7 1 0 0 1 1 1 0 Sporulation related domain p450 PF00067.22 ORY88428.1 - 1.9e-57 195.1 0.0 2.1e-57 194.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3767 PF12597.8 ORY88429.1 - 1.4e-32 111.5 0.0 1.4e-32 111.5 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) OsmC PF02566.19 ORY88430.1 - 4e-11 43.3 0.0 9.6e-11 42.1 0.0 1.6 2 0 0 2 2 2 1 OsmC-like protein Podoplanin PF05808.11 ORY88431.1 - 0.024 14.7 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Neurokinin_B PF03823.14 ORY88431.1 - 0.095 12.7 0.2 0.31 11.1 0.2 1.9 1 0 0 1 1 1 0 Neurokinin B PPI_Ypi1 PF07491.11 ORY88434.1 - 3e-26 91.0 0.3 6e-26 90.1 0.3 1.5 1 0 0 1 1 1 1 Protein phosphatase inhibitor Glyco_transf_90 PF05686.12 ORY88436.1 - 1.3e-14 54.0 0.2 2.1e-14 53.3 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Aminotran_3 PF00202.21 ORY88437.1 - 6.6e-116 387.3 0.0 7.5e-116 387.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY88437.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II MFS_1 PF07690.16 ORY88438.1 - 8.2e-35 120.4 59.8 3.2e-21 75.6 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 ORY88438.1 - 0.14 12.3 2.2 0.15 12.2 0.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Phage_holin_3_6 PF07332.11 ORY88438.1 - 0.15 12.1 0.1 0.15 12.1 0.1 4.3 4 2 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Hpt PF01627.23 ORY88440.1 - 2.2e-11 43.9 0.5 3.6e-11 43.2 0.5 1.4 1 0 0 1 1 1 1 Hpt domain NIBRIN_BRCT_II PF16508.5 ORY88440.1 - 0.14 12.4 0.4 0.49 10.7 0.0 1.9 1 1 1 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein CPP1-like PF11833.8 ORY88441.1 - 0.2 11.3 0.2 0.29 10.8 0.2 1.3 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Wzy_C PF04932.15 ORY88441.1 - 0.57 9.8 3.4 0.41 10.3 1.0 1.9 2 0 0 2 2 2 0 O-Antigen ligase 2TM PF13239.6 ORY88441.1 - 4.3 7.7 6.9 9.6 6.6 2.1 2.4 2 0 0 2 2 2 0 2TM domain DUF2518 PF10726.9 ORY88442.1 - 5.8 6.6 5.7 11 5.6 5.7 1.4 1 0 0 1 1 1 0 Protein of function (DUF2518) RasGAP PF00616.19 ORY88443.1 - 1e-35 123.4 0.1 9.8e-35 120.2 0.0 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 ORY88443.1 - 5.2e-34 117.3 3.4 6.7e-26 91.1 2.5 2.6 2 0 0 2 2 2 2 RasGAP C-terminus CH PF00307.31 ORY88443.1 - 2.1e-09 37.6 0.0 6.4e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 ORY88443.1 - 3.7e-09 35.6 28.2 0.17 11.7 0.0 8.3 9 0 0 9 9 9 6 IQ calmodulin-binding motif HSF_DNA-bind PF00447.17 ORY88444.1 - 2.5e-13 50.5 0.0 3.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding MFS_1 PF07690.16 ORY88445.1 - 5.3e-37 127.6 59.5 2.5e-22 79.3 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.11 ORY88445.1 - 0.036 14.1 0.2 0.17 12.0 0.1 2.2 2 2 0 2 2 2 0 Protein of unknown function (DUF962) Phage_holin_3_6 PF07332.11 ORY88445.1 - 0.037 14.1 0.1 0.037 14.1 0.1 4.2 4 2 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III TauD PF02668.16 ORY88446.1 - 6.1e-23 82.0 1.1 1.5e-22 80.7 1.1 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fimbrial_PilY2 PF14481.6 ORY88446.1 - 0.04 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 DUF3445 PF11927.8 ORY88449.1 - 2.5e-65 220.3 0.0 3.1e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF1804 PF08822.11 ORY88449.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) Glyco_hydro_26 PF02156.15 ORY88450.1 - 3.2e-10 39.9 0.9 5.4e-10 39.2 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Pex14_N PF04695.13 ORY88451.1 - 0.015 16.0 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRIMA1 PF16101.5 ORY88451.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF4391 PF14335.6 ORY88452.1 - 0.017 14.8 1.5 0.017 14.8 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4391) Macoilin PF09726.9 ORY88452.1 - 0.043 12.4 23.2 0.063 11.8 23.2 1.2 1 0 0 1 1 1 0 Macoilin family CENP-Q PF13094.6 ORY88452.1 - 0.65 10.2 28.0 2.2 8.5 11.7 2.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2730 PF10805.8 ORY88452.1 - 3.4 7.8 7.1 2.2 8.4 0.5 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 ORY88452.1 - 6.3 7.3 13.2 6.4 7.3 0.2 4.8 4 2 0 4 4 4 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 ORY88452.1 - 6.6 5.5 30.6 2 7.2 8.6 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein SseC PF04888.12 ORY88453.1 - 8.9 5.8 5.8 3.8 7.0 3.9 1.3 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family BET PF17035.5 ORY88454.1 - 0.069 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation PRANC PF09372.10 ORY88454.1 - 0.17 12.3 0.1 0.38 11.1 0.0 1.6 2 0 0 2 2 2 0 PRANC domain Ferric_reduct PF01794.19 ORY88457.1 - 3.2e-20 72.5 7.8 7.7e-20 71.3 7.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY88457.1 - 3.2e-12 46.8 0.0 5.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY88457.1 - 9.7e-12 44.9 0.0 7.3e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain XG_FTase PF03254.13 ORY88458.1 - 1e-10 40.9 0.0 5.5e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase DUF4611 PF15387.6 ORY88458.1 - 0.15 12.3 4.3 0.41 10.9 4.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) F-box-like PF12937.7 ORY88460.1 - 0.001 18.9 0.7 0.0023 17.8 0.7 1.6 1 0 0 1 1 1 1 F-box-like SseC PF04888.12 ORY88461.1 - 8.9 5.8 5.8 3.8 7.0 3.9 1.3 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family zf-CCHC_3 PF13917.6 ORY88462.1 - 1.9e-12 46.9 1.8 4.3e-12 45.8 1.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Aa_trans PF01490.18 ORY88464.1 - 1e-35 123.2 29.3 1.3e-35 122.9 29.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein His_Phos_1 PF00300.22 ORY88465.1 - 3.4e-29 101.9 0.1 4.9e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_transf_90 PF05686.12 ORY88466.1 - 6.5e-08 31.9 5.6 0.00081 18.4 2.5 4.8 3 1 0 3 3 3 3 Glycosyl transferase family 90 Eaf7 PF07904.13 ORY88467.1 - 3.9e-06 27.2 12.7 0.0003 21.1 12.6 3.1 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 Sulf_transp PF04143.14 ORY88468.1 - 5.3e-05 22.9 32.6 0.0022 17.6 13.9 3.4 2 2 1 3 3 3 3 Sulphur transport Cofilin_ADF PF00241.20 ORY88469.1 - 2.2e-43 146.9 0.2 2.5e-43 146.7 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Zn_clus PF00172.18 ORY88471.1 - 5.5e-07 29.6 11.0 5.5e-07 29.6 11.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4596 PF15363.6 ORY88471.1 - 0.25 11.6 1.5 4.1 7.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4596) NTP_transferase PF00483.23 ORY88473.1 - 1.1e-29 103.8 0.0 1.6e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORY88473.1 - 5.1e-09 35.5 0.4 2.5e-06 27.0 0.5 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY88473.1 - 9.5e-08 32.5 0.0 1.5e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 ORY88473.1 - 0.09 10.9 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Glyco_tranf_2_3 PF13641.6 ORY88473.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Fucokinase PF07959.12 ORY88473.1 - 0.26 10.2 0.8 1.4 7.8 0.3 2.0 2 0 0 2 2 2 0 L-fucokinase SEP PF08059.13 ORY88474.1 - 2.1e-24 85.9 0.0 4.1e-24 85.0 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 ORY88474.1 - 1.2e-16 60.6 0.0 1.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 UBX domain BRO1 PF03097.18 ORY88475.1 - 6.1e-91 305.1 0.0 9e-91 304.6 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY88475.1 - 6.2e-78 262.1 3.0 8.9e-78 261.6 3.0 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Alpha-amylase PF00128.24 ORY88476.1 - 1.5e-101 340.4 0.0 3.7e-101 339.0 0.0 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 ORY88476.1 - 0.00026 21.0 0.1 0.00075 19.6 0.0 1.8 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 ORY88476.1 - 0.0038 16.4 0.0 0.0068 15.5 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 ORY88476.1 - 0.0088 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Glyco_hydro_42C PF08533.10 ORY88476.1 - 0.017 14.8 0.0 0.052 13.3 0.0 1.7 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Glyco_hydro_114 PF03537.13 ORY88476.1 - 0.031 13.6 0.1 0.84 8.9 0.0 2.2 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 Sugar_tr PF00083.24 ORY88477.1 - 6.7e-86 288.9 21.8 7.8e-86 288.7 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY88477.1 - 3.4e-18 65.7 28.1 3.4e-18 65.7 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Complex1_LYR PF05347.15 ORY88478.1 - 0.0015 18.5 0.0 0.0032 17.5 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Metallophos PF00149.28 ORY88479.1 - 8.6e-10 39.5 2.2 1.6e-09 38.5 2.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1857 PF08982.11 ORY88480.1 - 4e-42 143.5 0.0 4.6e-42 143.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Polyketide_cyc2 PF10604.9 ORY88480.1 - 0.018 15.3 0.1 0.035 14.4 0.1 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Aa_trans PF01490.18 ORY88481.1 - 1.9e-35 122.4 32.8 2.2e-35 122.1 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_L35p PF01632.19 ORY88482.1 - 3.9e-15 56.1 1.3 6.1e-15 55.5 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L35 F-box-like PF12937.7 ORY88483.1 - 1e-06 28.5 0.1 3.9e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY88483.1 - 0.0015 18.4 0.1 0.0044 16.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 ORY88485.1 - 2.8e-61 207.2 0.0 3.3e-60 203.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88485.1 - 5.4e-35 120.9 0.0 1e-34 120.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 ORY88485.1 - 2.2e-22 78.9 9.4 3.5e-11 43.1 0.9 2.8 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 ORY88485.1 - 8.8e-20 70.3 22.6 1.4e-11 44.1 9.6 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 ORY88485.1 - 3.7e-11 43.5 3.9 4.6e-11 43.2 1.8 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 ORY88485.1 - 6.5e-07 29.6 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 ORY88485.1 - 0.037 13.3 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 ORY88485.1 - 0.041 13.5 1.0 2.2 7.9 0.2 2.8 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY88485.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING-like PF08746.11 ORY88485.1 - 1.9 8.8 20.3 6.7 7.1 8.8 2.4 2 0 0 2 2 2 0 RING-like domain Endosulfine PF04667.17 ORY88486.1 - 3.5e-25 87.9 0.1 5.1e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region MFS_1 PF07690.16 ORY88487.1 - 4.1e-35 121.3 32.0 4.1e-35 121.3 32.0 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 ORY88488.1 - 7.3e-46 156.7 0.0 4.1e-44 150.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SBP_bac_8 PF13416.6 ORY88488.1 - 0.018 14.9 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein rhaM PF05336.13 ORY88488.1 - 0.098 12.7 0.0 0.39 10.8 0.0 2.0 1 1 0 1 1 1 0 L-rhamnose mutarotase Glyoxalase PF00903.25 ORY88489.1 - 3.3e-12 46.7 0.0 4.9e-12 46.2 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY88489.1 - 1e-11 45.1 0.0 2.1e-11 44.1 0.0 1.5 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORY88489.1 - 2.6e-06 28.2 0.0 3.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 ORY88489.1 - 0.00017 21.7 0.0 0.00045 20.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain NTP_transf_5 PF14907.6 ORY88489.1 - 0.0072 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase Glyoxalase_2 PF12681.7 ORY88489.1 - 0.058 13.3 0.0 1.5 8.8 0.0 2.2 2 1 0 2 2 2 0 Glyoxalase-like domain PS_pyruv_trans PF04230.13 ORY88490.1 - 7.8e-21 75.2 0.1 1.6e-20 74.2 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide pyruvyl transferase TPT PF03151.16 ORY88491.1 - 6.7e-12 45.4 17.9 8.1e-12 45.1 17.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY88491.1 - 0.055 12.7 10.4 0.027 13.7 8.1 1.6 1 1 1 2 2 2 0 UAA transporter family NAD_binding_4 PF07993.12 ORY88492.1 - 1.3e-33 116.3 0.0 2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ORY88492.1 - 1.9e-31 109.1 0.0 3.3e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 ORY88492.1 - 1.8e-09 37.4 0.0 3.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 ORY88492.1 - 8e-09 35.7 0.0 2.5e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 ORY88492.1 - 0.0011 19.0 0.4 0.0051 16.7 0.4 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 ORY88492.1 - 0.13 11.3 0.1 1.7 7.6 0.1 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY88492.1 - 0.18 10.9 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.18 ORY88493.1 - 3.6e-13 49.2 0.1 7.4e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY88493.1 - 3.9e-09 36.5 9.9 8.4e-09 35.4 9.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 ORY88493.1 - 6.1e-05 23.2 5.9 0.0079 16.6 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY88493.1 - 0.00033 21.3 5.6 0.017 15.9 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY88493.1 - 0.0012 18.7 0.2 0.0029 17.6 0.2 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY88493.1 - 0.036 14.5 0.7 0.036 14.5 0.7 2.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 ORY88493.1 - 0.063 14.0 0.3 0.13 12.9 0.3 1.4 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 ORY88493.1 - 0.11 12.2 0.7 0.37 10.6 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain FOXP-CC PF16159.5 ORY88493.1 - 0.18 12.5 0.7 12 6.6 0.2 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain Aldo_ket_red PF00248.21 ORY88494.1 - 3e-45 154.7 0.0 1.7e-43 148.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family SBP_bac_8 PF13416.6 ORY88494.1 - 0.019 14.8 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein ACP PF06857.11 ORY88494.1 - 0.15 12.3 0.0 0.44 10.8 0.0 1.8 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) MFS_1 PF07690.16 ORY88495.1 - 3.9e-33 114.8 29.3 5.9e-33 114.2 29.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ufd2P_core PF10408.9 ORY88496.1 - 4.1e-203 676.5 0.0 5.8e-203 676.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 ORY88496.1 - 4.4e-26 90.8 0.3 1.3e-25 89.4 0.3 1.9 1 0 0 1 1 1 1 U-box domain DAO PF01266.24 ORY88497.1 - 4e-36 125.3 1.1 4.6e-36 125.1 1.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Cys_Met_Meta_PP PF01053.20 ORY88498.1 - 3.3e-56 190.5 0.0 1.1e-55 188.7 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.18 ORY88499.1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY88499.1 - 0.0002 21.4 12.7 0.00032 20.8 12.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLAC8 PF04749.17 ORY88502.1 - 2.6e-13 50.8 0.5 3.7e-13 50.3 0.5 1.2 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 ORY88504.1 - 3.3e-21 76.1 9.6 4.2e-21 75.8 9.6 1.1 1 0 0 1 1 1 1 PLAC8 family DUF4344 PF14247.6 ORY88504.1 - 0.14 11.8 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase RNase_P_Rpp14 PF01900.19 ORY88505.1 - 9.9e-32 109.3 0.0 1.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP-synt_ab PF00006.25 ORY88506.1 - 3.5e-66 222.9 0.0 5.4e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY88506.1 - 4.3e-12 46.4 0.5 8.9e-12 45.4 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 ORY88506.1 - 0.0088 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5535) DUF3533 PF12051.8 ORY88506.1 - 0.038 12.9 0.0 0.063 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) RNase_P_Rpp14 PF01900.19 ORY88507.1 - 9.9e-32 109.3 0.0 1.3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Sugar_tr PF00083.24 ORY88508.1 - 4.1e-116 388.5 21.7 4.7e-116 388.3 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY88508.1 - 4.9e-14 52.0 31.1 4.9e-14 52.0 31.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S26 PF10502.9 ORY88510.1 - 2.4e-08 33.9 0.0 5.8e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 ORY88510.1 - 0.0028 17.6 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF4504 PF14953.6 ORY88511.1 - 5.5e-05 22.7 0.0 0.00021 20.8 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) RhoGAP PF00620.27 ORY88513.1 - 8.4e-27 93.9 0.0 1.4e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TFIIS_C PF01096.18 ORY88514.1 - 8.2e-16 57.6 5.7 8.2e-16 57.6 5.7 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORY88514.1 - 4.2e-08 32.9 2.3 4.2e-08 32.9 2.3 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit YqaJ PF09588.10 ORY88515.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 YqaJ-like viral recombinase domain Cyclin_N PF00134.23 ORY88516.1 - 3.4e-14 52.7 0.1 5.1e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY88516.1 - 4.6e-08 33.6 0.0 8.5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin Gly_transf_sug PF04488.15 ORY88517.1 - 0.00018 22.0 0.0 0.00037 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY88517.1 - 0.079 12.3 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DLH PF01738.18 ORY88518.1 - 1.4e-13 50.9 0.0 4.3e-13 49.3 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORY88518.1 - 0.11 13.1 0.1 0.14 12.7 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY88518.1 - 0.15 11.7 0.1 0.21 11.2 0.1 1.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 ORY88519.1 - 2.8e-79 267.0 0.0 3.5e-79 266.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mut7-C PF01927.16 ORY88520.1 - 0.022 14.9 0.1 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 Mut7-C RNAse domain EzrA PF06160.12 ORY88520.1 - 0.18 10.0 0.2 0.22 9.6 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-TFIIB PF13453.6 ORY88520.1 - 1.5 8.2 5.3 8 5.9 0.9 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger CENP-R PF06729.12 ORY88543.1 - 0.031 14.2 0.8 0.031 14.2 0.8 1.7 2 0 0 2 2 2 0 Kinetochore component, CENP-R FAM176 PF14851.6 ORY88543.1 - 0.21 11.3 1.8 0.29 10.8 1.8 1.1 1 0 0 1 1 1 0 FAM176 family zf-RING_2 PF13639.6 ORY88544.1 - 1.5e-11 44.4 6.9 2.8e-11 43.6 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.22 ORY88544.1 - 7.2e-10 38.8 0.0 2e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 PA domain zf-RING_11 PF17123.5 ORY88544.1 - 1.1e-08 34.6 3.5 2.1e-08 33.8 3.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY88544.1 - 1.1e-06 28.4 6.5 2.1e-06 27.5 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY88544.1 - 5.7e-06 26.2 3.6 9e-06 25.6 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY88544.1 - 3.2e-05 23.7 5.4 4.9e-05 23.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY88544.1 - 0.00036 20.5 4.8 0.00079 19.4 4.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY88544.1 - 0.0015 18.8 6.6 0.0045 17.2 6.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY88544.1 - 0.0016 18.4 0.9 0.0037 17.3 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY88544.1 - 0.0018 18.1 3.7 0.0042 16.9 3.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY88544.1 - 1.1 9.5 3.9 5.4 7.3 3.1 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORY88544.1 - 4 7.4 10.5 1.8 8.5 3.7 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 adh_short PF00106.25 ORY88545.1 - 1.3e-36 125.9 0.0 1.9e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88545.1 - 2.9e-24 85.9 0.0 5e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY88545.1 - 0.0001 21.9 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORY88545.1 - 0.0006 19.8 0.4 1.3 8.9 0.0 2.2 2 0 0 2 2 2 2 KR domain RmlD_sub_bind PF04321.17 ORY88545.1 - 0.058 12.5 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY88545.1 - 0.058 12.4 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ribosomal_L24e PF01246.20 ORY88546.1 - 7.9e-30 102.9 7.1 1.6e-29 101.9 7.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e TT_ORF2 PF02957.15 ORY88546.1 - 0.026 15.4 0.5 0.047 14.6 0.5 1.6 1 0 0 1 1 1 0 TT viral ORF2 COesterase PF00135.28 ORY88551.1 - 1.7e-55 188.9 1.0 1.6e-53 182.3 1.0 2.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY88551.1 - 9.2e-05 22.4 0.0 0.00043 20.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2673 PF10880.8 ORY88551.1 - 0.04 14.0 0.7 0.086 13.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) EcoRII-N PF09217.10 ORY88551.1 - 0.06 13.1 0.3 0.31 10.8 0.1 2.3 2 1 0 2 2 2 0 Restriction endonuclease EcoRII, N-terminal Pyr_redox_2 PF07992.14 ORY88552.1 - 4.2e-43 147.7 0.0 6.3e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY88552.1 - 1.1e-11 45.2 0.0 5.6e-10 39.6 0.0 3.2 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 ORY88552.1 - 1.8e-05 23.9 1.3 5.2e-05 22.5 1.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORY88552.1 - 7.8e-05 22.3 1.2 0.0011 18.7 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 ORY88552.1 - 0.00084 18.7 0.3 0.0021 17.5 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORY88552.1 - 0.0012 19.3 0.5 0.0025 18.2 0.5 1.6 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 ORY88552.1 - 0.0027 17.0 0.1 0.036 13.3 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_8 PF13833.6 ORY88552.1 - 0.069 13.0 1.0 0.19 11.6 1.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_4 PF12763.7 ORY88552.1 - 0.14 12.1 0.6 1.4 8.9 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand MFS_1 PF07690.16 ORY88553.1 - 2.6e-34 118.7 61.8 1.2e-33 116.6 59.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY88553.1 - 3.9e-09 35.5 16.3 2.1e-08 33.1 17.9 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY88553.1 - 1.4e-07 30.7 11.2 1.4e-07 30.7 11.2 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 ORY88553.1 - 0.15 10.3 3.1 0.97 7.6 1.1 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family YebO PF13974.6 ORY88553.1 - 0.23 11.6 0.7 28 4.9 0.1 2.6 2 0 0 2 2 2 0 YebO-like protein Wzz PF02706.15 ORY88553.1 - 6.5 7.1 5.4 50 4.3 1.0 2.9 2 0 0 2 2 2 0 Chain length determinant protein adh_short PF00106.25 ORY88554.1 - 1.5e-25 89.8 0.0 1.2e-22 80.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88554.1 - 2.8e-15 56.5 0.0 1.9e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY88554.1 - 1.4e-06 28.3 0.0 3e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORY88554.1 - 0.0034 16.9 0.1 0.2 11.1 0.1 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY88554.1 - 0.0093 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 ORY88554.1 - 0.094 13.7 0.0 0.65 11.0 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.15 ORY88554.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HOOK PF05622.12 ORY88555.1 - 2.8e-61 207.6 86.2 1.2e-58 198.9 48.5 2.9 1 1 0 2 2 2 2 HOOK protein Fib_alpha PF08702.10 ORY88555.1 - 0.018 15.2 3.6 0.018 15.2 3.6 6.6 3 2 3 7 7 7 0 Fibrinogen alpha/beta chain family HTH_Tnp_Tc3_1 PF11427.8 ORY88555.1 - 0.11 12.3 0.0 0.38 10.7 0.0 2.0 1 0 0 1 1 1 0 Tc3 transposase DUF4108 PF13390.6 ORY88555.1 - 0.5 10.3 0.0 0.5 10.3 0.0 4.1 3 1 0 4 4 4 0 Protein of unknown function (DUF4108) TssO PF17561.2 ORY88555.1 - 8.3 6.5 20.7 3.8 7.6 0.5 3.8 2 1 0 3 3 3 0 Type VI secretion system, TssO adh_short PF00106.25 ORY88558.1 - 1.6e-24 86.5 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88558.1 - 4.4e-17 62.4 0.0 7.8e-16 58.3 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY88558.1 - 0.13 12.2 1.2 8.3 6.3 0.0 2.2 2 0 0 2 2 2 0 KR domain Sld5 PF05916.11 ORY88559.1 - 2e-20 73.3 0.0 3.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Fe-S_biosyn PF01521.20 ORY88560.1 - 2.6e-11 43.7 0.0 5.7e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis MFS_1 PF07690.16 ORY88561.1 - 3.8e-24 85.3 28.5 9.3e-24 84.0 28.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY88561.1 - 3.6e-05 23.2 3.6 3.6e-05 23.2 3.6 1.4 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB YrhC PF14143.6 ORY88561.1 - 1.6 8.9 3.4 65 3.7 0.0 3.6 4 0 0 4 4 4 0 YrhC-like protein DUF3120 PF11318.8 ORY88561.1 - 2.5 8.4 8.3 0.59 10.4 1.9 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3120) Complex1_LYR PF05347.15 ORY88562.1 - 2.6e-07 30.6 1.2 4e-07 30.0 0.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 ORY88562.1 - 0.0017 18.9 0.3 0.0031 18.1 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 ORY88562.1 - 0.025 15.3 0.6 0.058 14.1 0.2 1.8 2 0 0 2 2 2 0 Complex1_LYR-like BNIP3 PF06553.12 ORY88562.1 - 1.1 8.8 6.5 1.5 8.5 6.5 1.3 1 1 0 1 1 1 0 BNIP3 Zn_clus PF00172.18 ORY88565.1 - 0.003 17.6 8.8 0.0045 17.1 8.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPA_C PF05181.12 ORY88566.1 - 0.0027 17.6 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 2 XPA protein C-terminus DUF3727 PF12527.8 ORY88566.1 - 0.036 14.3 0.2 0.078 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) NAD_binding_1 PF00175.21 ORY88566.1 - 0.12 13.0 0.8 24 5.6 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3987 PF13148.6 ORY88566.1 - 8.8 5.2 8.9 13 4.7 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Atrophin-1 PF03154.15 ORY88568.1 - 0.063 11.6 3.4 0.069 11.4 3.4 1.3 1 0 0 1 1 1 0 Atrophin-1 family Zn_clus PF00172.18 ORY88569.1 - 0.0058 16.7 8.5 0.011 15.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPA_C PF05181.12 ORY88570.1 - 0.00016 21.6 0.0 0.031 14.2 0.0 2.4 2 0 0 2 2 2 1 XPA protein C-terminus NAD_binding_1 PF00175.21 ORY88570.1 - 0.063 13.9 1.3 8.2 7.1 1.7 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2540 PF10802.8 ORY88570.1 - 0.1 12.7 1.9 0.17 12.0 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) DUF2815 PF10991.8 ORY88570.1 - 0.18 11.7 5.2 0.32 10.9 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) RXT2_N PF08595.11 ORY88570.1 - 0.26 11.3 10.3 3.1 7.8 6.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF3987 PF13148.6 ORY88570.1 - 1.3 8.0 8.0 1.8 7.5 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FYDLN_acid PF09538.10 ORY88570.1 - 2.1 9.1 14.9 5 7.9 10.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.8 ORY88570.1 - 5.3 7.2 18.6 2.7 8.2 13.2 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 ORY88570.1 - 5.3 6.8 15.3 21 4.8 12.1 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 ORY88570.1 - 7.7 5.7 14.4 2.2 7.5 5.8 2.1 2 0 0 2 2 2 0 NOA36 protein Afi1 PF07792.12 ORY88570.1 - 7.7 7.0 8.9 36 4.9 5.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FACT-Spt16_Nlob PF14826.6 ORY88571.1 - 4.3e-52 176.1 0.0 1.1e-51 174.8 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 ORY88571.1 - 2.8e-51 173.7 0.1 2.8e-51 173.7 0.1 2.5 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 ORY88571.1 - 1.9e-29 102.8 0.0 3.5e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 ORY88571.1 - 2e-15 57.0 0.0 3.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.6 ORY88571.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Arc_PepC PF06819.11 ORY88571.1 - 0.057 13.6 0.2 0.23 11.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain Amidase02_C PF12123.8 ORY88571.1 - 0.091 12.5 0.0 0.61 9.8 0.0 2.3 3 0 0 3 3 3 0 N-acetylmuramoyl-l-alanine amidase YL1 PF05764.13 ORY88571.1 - 2.4 8.2 41.2 0.11 12.6 20.4 3.6 3 0 0 3 3 3 0 YL1 nuclear protein OPT PF03169.15 ORY88572.1 - 8.7e-155 516.8 47.0 1.1e-154 516.5 47.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 ORY88573.1 - 1.4e-185 618.6 53.6 1.6e-185 618.4 53.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AHL_synthase PF17327.2 ORY88573.1 - 0.24 10.4 0.6 0.35 9.8 0.6 1.1 1 0 0 1 1 1 0 Acyl homoserine lactone synthase DUF3461 PF11944.8 ORY88574.1 - 0.017 15.3 0.2 23 5.2 0.0 4.1 1 1 6 7 7 7 0 Protein of unknown function (DUF3461) P22_CoatProtein PF11651.8 ORY88574.1 - 0.3 9.6 0.1 0.39 9.3 0.1 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 Peptidase_S9 PF00326.21 ORY88575.1 - 4e-06 26.4 0.0 8.2e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY88575.1 - 0.00077 18.8 0.1 0.0026 17.0 0.3 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY88575.1 - 0.0038 16.9 0.1 0.0084 15.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 ORY88575.1 - 0.0094 15.1 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF790 PF05626.11 ORY88575.1 - 0.025 13.3 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) VPS11_C PF12451.8 ORY88576.1 - 9.9e-12 44.9 0.2 1.9e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 ORY88576.1 - 1.5e-10 41.1 0.0 0.0037 17.2 0.0 3.5 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 ORY88576.1 - 2.4e-10 40.3 6.4 4.3e-10 39.5 6.4 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 ORY88576.1 - 0.0071 16.2 6.1 0.012 15.4 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY88576.1 - 0.025 14.9 6.3 0.046 14.1 6.3 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 ORY88576.1 - 0.044 13.7 6.3 0.078 13.0 6.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY88576.1 - 1.7 8.8 6.5 3.2 7.8 6.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 ORY88576.1 - 1.7 9.0 5.3 3.2 8.1 5.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Atg8 PF02991.16 ORY88577.1 - 4.6e-52 174.6 0.1 5.3e-52 174.3 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ORY88577.1 - 4.1e-07 30.3 0.0 5.2e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_9 PF14604.6 ORY88577.1 - 0.15 11.9 0.0 8 6.4 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain LRR_6 PF13516.6 ORY88578.1 - 0.00099 19.0 2.0 10 6.5 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 ORY88578.1 - 0.073 13.5 3.4 3.8 8.1 0.0 3.2 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) XPA_C PF05181.12 ORY88579.1 - 0.013 15.4 0.2 2.4 8.2 0.1 2.4 2 0 0 2 2 2 0 XPA protein C-terminus Trypan_PARP PF05887.11 ORY88579.1 - 0.82 9.7 14.4 0.28 11.2 7.3 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Aa_trans PF01490.18 ORY88580.1 - 7.9e-35 120.3 27.1 9.8e-35 120.0 27.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5562 PF17717.1 ORY88580.1 - 0.19 11.7 5.3 0.25 11.3 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5562) F-box-like PF12937.7 ORY88582.1 - 0.0004 20.2 0.4 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like GRP PF07172.11 ORY88582.1 - 0.0049 17.5 12.2 0.0049 17.5 12.2 2.0 2 0 0 2 2 2 1 Glycine rich protein family HTH_40 PF14493.6 ORY88582.1 - 0.013 16.0 0.8 0.039 14.4 0.1 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain F-box PF00646.33 ORY88582.1 - 0.029 14.3 0.1 0.11 12.4 0.1 2.0 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 ORY88582.1 - 0.035 14.0 0.3 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 F-box Aa_trans PF01490.18 ORY88583.1 - 1.2e-25 90.1 24.8 1.1e-24 86.9 24.8 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 ORY88583.1 - 0.59 8.9 14.2 7.5 5.3 14.2 2.6 1 1 0 1 1 1 0 Spore germination protein Aa_trans PF01490.18 ORY88584.1 - 4.8e-37 127.6 28.8 6.7e-37 127.2 28.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein K_channel_TID PF07941.11 ORY88586.1 - 2 8.9 6.1 5.2 7.6 6.1 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RhoGAP PF00620.27 ORY88587.1 - 2.7e-13 50.0 0.0 5.4e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain Exo_endo_phos PF03372.23 ORY88587.1 - 2.6e-07 30.4 0.0 5.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NeA_P2 PF12312.8 ORY88587.1 - 2.3 7.6 5.0 1.5 8.2 0.2 2.7 3 0 0 3 3 3 0 Nepovirus subgroup A polyprotein Tyr-DNA_phospho PF06087.12 ORY88588.1 - 7.1e-36 124.0 0.0 8e-35 120.5 0.0 1.9 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PWWP PF00855.17 ORY88589.1 - 3.9e-08 33.6 0.1 1.7e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 PWWP domain PRAS PF15798.5 ORY88589.1 - 5.2 7.7 10.5 0.71 10.5 5.0 2.3 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 GREB1 PF15782.5 ORY88589.1 - 9.9 3.1 8.4 12 2.8 8.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PWWP PF00855.17 ORY88590.1 - 3.3e-06 27.4 0.0 1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 PWWP domain Macoilin PF09726.9 ORY88590.1 - 0.015 13.9 2.1 0.013 14.1 2.1 1.1 1 0 0 1 1 1 0 Macoilin family Sec16 PF12932.7 ORY88590.1 - 0.33 11.5 4.1 1.5 9.4 4.1 2.2 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Ndc1_Nup PF09531.10 ORY88590.1 - 1.9 7.1 5.6 2.2 6.9 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FGGY_C PF02782.16 ORY88591.1 - 1.1e-63 214.5 1.8 2.2e-63 213.6 1.8 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY88591.1 - 4.3e-61 206.6 0.0 2.5e-60 204.1 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain EBP PF05241.12 ORY88593.1 - 1.3e-65 220.2 7.5 1.5e-65 220.0 7.5 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 ORY88593.1 - 0.0025 18.3 6.5 0.0032 17.9 6.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) XPA_C PF05181.12 ORY88595.1 - 1.4e-07 31.3 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus F-box-like PF12937.7 ORY88595.1 - 0.0022 17.8 0.4 0.009 15.9 0.4 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY88595.1 - 0.14 12.1 0.1 1.2 9.1 0.2 2.2 2 0 0 2 2 2 0 F-box domain F-box PF00646.33 ORY88597.1 - 0.00074 19.3 0.1 0.0018 18.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain TB PF00683.17 ORY88597.1 - 0.04 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 TB domain Chitin_synth_2 PF03142.15 ORY88598.1 - 1.4e-239 796.1 0.5 1.9e-239 795.7 0.5 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY88598.1 - 6.9e-78 262.5 0.0 1.1e-76 258.5 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY88598.1 - 3.4e-13 49.3 0.0 2.2e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 ORY88598.1 - 5.2e-12 45.8 0.8 4.3e-10 39.6 0.1 2.9 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 ORY88598.1 - 1.3e-11 44.9 0.0 7.1e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY88598.1 - 7.2e-11 42.4 3.9 1.7e-10 41.2 3.9 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY88598.1 - 7.3e-05 22.6 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY88598.1 - 0.06 12.8 0.2 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 RhoGAP PF00620.27 ORY88599.1 - 4.4e-28 98.0 0.0 6.7e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.11 ORY88599.1 - 0.075 12.2 0.2 0.17 11.0 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1708) Asp PF00026.23 ORY88600.1 - 1.3e-58 198.9 7.8 5e-43 147.7 5.3 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY88600.1 - 6.6e-08 33.0 8.1 4.5e-07 30.3 3.0 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Cytochrom_B561 PF03188.16 ORY88601.1 - 1.9e-15 57.2 3.6 3e-15 56.6 3.6 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 ORY88601.1 - 0.26 10.9 9.0 0.54 9.8 6.5 2.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Nucleos_tra2_N PF01773.20 ORY88601.1 - 0.46 11.1 5.8 2.7 8.6 0.9 3.1 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus F-box PF00646.33 ORY88602.1 - 0.00098 18.9 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 F-box domain TB PF00683.17 ORY88602.1 - 0.045 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 TB domain Acetyltransf_9 PF13527.7 ORY88604.1 - 0.003 17.6 0.1 0.0072 16.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY88604.1 - 0.028 14.5 0.5 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 ORY88604.1 - 0.083 13.1 0.1 21 5.4 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY88604.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GPI-anchored PF10342.9 ORY88605.1 - 6.2e-11 42.9 0.4 6.2e-11 42.9 0.4 2.4 3 0 0 3 3 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EphA2_TM PF14575.6 ORY88605.1 - 0.00036 21.4 1.5 0.012 16.4 0.0 3.4 4 0 0 4 4 3 1 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 ORY88605.1 - 0.0014 17.4 0.2 0.0035 16.2 0.0 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) TMEM51 PF15345.6 ORY88605.1 - 0.022 14.6 0.4 0.022 14.6 0.4 2.5 3 1 0 3 3 3 0 Transmembrane protein 51 RIFIN PF02009.16 ORY88605.1 - 0.024 14.6 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Rifin Adeno_E3_CR2 PF02439.15 ORY88605.1 - 0.071 12.9 1.3 0.21 11.3 1.3 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.20 ORY88605.1 - 0.1 12.5 0.5 0.95 9.4 0.1 2.5 2 0 0 2 2 2 0 Syndecan domain Macoilin PF09726.9 ORY88605.1 - 0.16 10.5 3.6 0.26 9.8 3.6 1.3 1 0 0 1 1 1 0 Macoilin family Stevor PF17410.2 ORY88605.1 - 0.26 10.8 0.1 0.52 9.8 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Cytomega_TRL10 PF06084.11 ORY88605.1 - 0.59 10.1 2.1 0.47 10.5 0.1 1.8 2 0 0 2 2 2 0 Cytomegalovirus TRL10 protein TMEM154 PF15102.6 ORY88605.1 - 0.85 9.5 6.3 0.13 12.2 1.1 2.3 2 1 0 2 2 2 0 TMEM154 protein family DUF1180 PF06679.12 ORY88605.1 - 0.96 9.8 9.7 0.053 14.0 1.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Apt1 PF10351.9 ORY88605.1 - 3.2 6.5 7.4 0.27 10.0 2.2 1.8 3 0 0 3 3 3 0 Golgi-body localisation protein domain Ribosomal_L5e PF17144.4 ORY88606.1 - 1.1e-77 259.6 3.9 8.6e-77 256.7 3.9 2.1 1 1 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORY88606.1 - 6.7e-32 110.3 4.4 6.7e-32 110.3 4.4 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.6 ORY88606.1 - 0.031 14.5 2.6 0.044 14.0 0.6 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus NAD_Gly3P_dh_C PF07479.14 ORY88607.1 - 1.7e-48 164.5 0.0 2.9e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 ORY88607.1 - 1.9e-28 99.4 0.0 2.7e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 ORY88607.1 - 0.016 15.8 0.0 0.14 12.7 0.0 2.5 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Retinin_C PF04527.12 ORY88607.1 - 0.17 12.2 0.7 0.41 10.9 0.2 1.8 2 0 0 2 2 2 0 Drosophila Retinin like protein RNA12 PF10443.9 ORY88608.1 - 1.9e-120 402.6 0.1 2e-72 244.3 0.0 2.2 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 ORY88608.1 - 2.2e-06 27.8 0.0 5.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 ORY88608.1 - 2.3e-06 27.3 0.0 1e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 ORY88608.1 - 8.6e-06 26.2 0.0 3.2e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY88608.1 - 0.00013 22.2 0.0 0.00033 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY88608.1 - 0.00056 20.1 0.0 0.17 12.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY88608.1 - 0.00082 19.8 0.0 0.0026 18.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY88608.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY88608.1 - 0.018 14.6 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 ORY88608.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 ORY88608.1 - 0.028 13.6 0.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 ORY88608.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PepSY_2 PF13670.6 ORY88608.1 - 0.26 11.3 3.9 0.72 9.9 0.7 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain AAA_23 PF13476.6 ORY88608.1 - 0.4 11.1 1.8 7.1 7.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ribosomal_L5e PF17144.4 ORY88609.1 - 4.3e-77 257.7 3.4 3.4e-76 254.8 3.4 2.1 1 1 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORY88609.1 - 6.7e-32 110.3 4.4 6.7e-32 110.3 4.4 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.6 ORY88609.1 - 0.027 14.7 2.2 0.044 14.0 0.6 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus CRM1_C PF08767.11 ORY88611.1 - 2.6e-124 414.6 0.0 1.5e-123 412.0 0.0 2.3 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 ORY88611.1 - 1.1e-39 135.8 5.0 5.4e-39 133.6 4.7 2.5 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 ORY88611.1 - 5.3e-33 112.5 3.6 1.3e-32 111.3 3.6 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 ORY88611.1 - 5.1e-30 103.3 1.9 1.1e-29 102.3 0.7 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 ORY88611.1 - 2e-20 72.0 2.5 4.6e-20 70.8 2.5 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 ORY88611.1 - 1.4e-15 57.0 0.3 8.3e-15 54.5 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain F-box-like PF12937.7 ORY88614.1 - 0.039 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like Rad60-SLD PF11976.8 ORY88615.1 - 0.0026 17.5 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like F-box PF00646.33 ORY88616.1 - 0.0029 17.5 0.7 0.0029 17.5 0.7 2.3 2 0 0 2 2 2 1 F-box domain Acetyltransf_9 PF13527.7 ORY88617.1 - 0.0063 16.6 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY88617.1 - 0.045 14.2 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY88617.1 - 0.079 13.2 0.0 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 ORY88617.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family Pkinase PF00069.25 ORY88619.1 - 0.0011 18.4 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Glycophorin_A PF01102.18 ORY88621.1 - 4.7e-05 23.6 0.2 7e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 Glycophorin A SKG6 PF08693.10 ORY88621.1 - 0.0076 15.6 0.2 0.0076 15.6 0.2 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Mid2 PF04478.12 ORY88621.1 - 0.035 13.9 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2649 PF10854.8 ORY88621.1 - 0.048 14.0 0.2 0.083 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) FSA_C PF10479.9 ORY88621.1 - 1.1 7.4 6.0 1.2 7.2 6.0 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Rad60-SLD PF11976.8 ORY88622.1 - 0.0059 16.4 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like F-box PF00646.33 ORY88623.1 - 0.01 15.7 0.8 0.023 14.6 0.2 1.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 ORY88623.1 - 0.079 12.9 0.7 0.51 10.3 0.0 2.6 3 0 0 3 3 3 0 F-box-like Dynactin PF12455.8 ORY88624.1 - 7.2e-93 310.9 3.8 7.2e-93 310.9 3.8 4.0 4 0 0 4 4 4 2 Dynein associated protein CAP_GLY PF01302.25 ORY88624.1 - 6.2e-23 80.6 0.4 1.1e-22 79.7 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain BBS1 PF14779.6 ORY88624.1 - 3 7.2 9.2 1.7 8.0 1.4 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 Glyco_hydro_16 PF00722.21 ORY88625.1 - 2.4e-35 121.6 0.1 3.8e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 ORY88625.1 - 0.023 15.2 10.6 0.051 14.1 10.6 1.5 1 0 0 1 1 1 0 Chitin recognition protein adh_short PF00106.25 ORY88626.1 - 2.7e-31 108.5 0.1 5.4e-31 107.6 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88626.1 - 6.7e-27 94.6 0.1 1.4e-25 90.2 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY88626.1 - 4e-08 33.4 1.1 4.6e-08 33.2 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 ORY88626.1 - 0.00033 20.2 0.1 0.00049 19.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ORY88626.1 - 0.004 17.1 0.3 0.0056 16.6 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ORY88626.1 - 0.046 13.1 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AdoHcyase_NAD PF00670.21 ORY88626.1 - 0.062 13.4 2.6 0.12 12.4 2.6 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CENP-I PF07778.11 ORY88627.1 - 1.3e-08 34.1 0.2 3e-06 26.3 0.1 3.4 2 2 0 2 2 2 1 Mis6 F-box PF00646.33 ORY88627.1 - 0.00022 21.0 0.0 0.0006 19.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY88627.1 - 0.0013 18.5 1.9 0.0021 17.9 0.0 2.4 2 0 0 2 2 2 1 F-box-like Fic_N PF13784.6 ORY88627.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 Fic/DOC family N-terminal EF-hand_4 PF12763.7 ORY88628.1 - 3.9e-34 116.7 0.0 2e-12 46.9 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 ORY88628.1 - 1.4e-06 28.1 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.6 ORY88628.1 - 3.2e-06 27.5 0.0 6.6 7.3 0.0 5.0 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY88628.1 - 8.7e-05 21.8 0.0 2 8.2 0.0 4.8 5 0 0 5 5 5 1 EF hand TPR_MLP1_2 PF07926.12 ORY88628.1 - 0.0029 17.7 17.0 0.0029 17.7 17.0 2.6 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein EF-hand_8 PF13833.6 ORY88628.1 - 0.0069 16.2 0.0 1.2 9.0 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair Vps51 PF08700.11 ORY88628.1 - 0.02 15.0 6.8 0.57 10.3 0.5 2.9 1 1 2 3 3 3 0 Vps51/Vps67 CENP-K PF11802.8 ORY88628.1 - 0.14 11.7 11.5 0.23 11.0 11.5 1.2 1 0 0 1 1 1 0 Centromere-associated protein K APG6_N PF17675.1 ORY88628.1 - 2.4 8.7 27.3 53 4.3 10.0 3.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 ORY88628.1 - 2.4 6.9 24.0 3.1 6.6 6.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 ORY88628.1 - 2.5 8.1 13.3 7.8 6.6 7.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 ORY88628.1 - 2.7 8.4 9.7 3.7 7.9 2.0 2.4 2 0 0 2 2 2 0 Tup N-terminal SOGA PF11365.8 ORY88628.1 - 5.1 8.3 16.3 0.55 11.4 6.4 2.7 2 0 0 2 2 2 0 Protein SOGA TMPIT PF07851.13 ORY88628.1 - 5.8 6.1 17.7 0.15 11.3 6.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein SPAM PF02090.15 ORY88628.1 - 6.8 6.5 14.8 1.4 8.7 3.8 2.2 1 1 1 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF724 PF05266.14 ORY88628.1 - 7.5 6.3 23.0 0.31 10.9 6.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 ORY88628.1 - 7.7 7.3 6.8 35 5.2 1.3 2.4 2 0 0 2 2 2 0 Occludin homology domain AAA_13 PF13166.6 ORY88628.1 - 8.9 4.8 12.2 15 4.0 12.2 1.3 1 0 0 1 1 1 0 AAA domain Formyl_trans_N PF00551.19 ORY88629.1 - 3.2e-33 115.0 1.9 4.1e-16 59.3 0.0 3.9 3 1 0 3 3 3 3 Formyl transferase F-box PF00646.33 ORY88630.1 - 2.4e-08 33.6 0.1 5.9e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY88630.1 - 8.5e-05 22.4 0.2 0.00021 21.1 0.1 1.7 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 ORY88630.1 - 0.00035 20.4 0.0 0.00091 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like Rad60-SLD PF11976.8 ORY88631.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY88631.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family AA_permease_2 PF13520.6 ORY88632.1 - 1.1e-86 291.4 42.3 1.3e-86 291.1 42.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY88632.1 - 1.5e-17 63.4 37.8 2e-17 63.0 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease FTR1 PF03239.14 ORY88632.1 - 0.48 9.5 10.1 0.048 12.8 4.8 2.0 2 0 0 2 2 2 0 Iron permease FTR1 family ATG_C PF09333.11 ORY88633.1 - 1.2e-36 124.9 0.0 3.4e-36 123.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 ORY88633.1 - 1.2e-12 47.9 0.0 5e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 ORY88633.1 - 1.6e-11 44.2 0.0 3.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif VPS13_C PF16909.5 ORY88633.1 - 0.00041 20.2 0.0 0.0014 18.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal F-box-like PF12937.7 ORY88634.1 - 3.8e-06 26.7 0.3 1e-05 25.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY88634.1 - 0.27 11.7 11.2 0.34 11.4 0.2 4.9 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3701 PF12482.8 ORY88636.1 - 0.067 13.3 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage integrase protein JmjC PF02373.22 ORY88637.1 - 7.3e-38 129.5 0.0 1.6e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 ORY88637.1 - 4.9e-14 52.3 1.7 1.1e-13 51.2 1.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 ORY88637.1 - 1.8e-13 50.6 2.1 3.3e-13 49.8 2.1 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 ORY88637.1 - 1.8e-11 43.8 1.7 1.8e-11 43.8 1.7 2.0 2 0 0 2 2 2 1 jmjN domain zf-RING-like PF08746.11 ORY88637.1 - 3.9 7.9 8.4 7.7 6.9 8.4 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 ORY88637.1 - 9.2 6.2 9.9 3.4 7.6 5.9 2.2 2 0 0 2 2 2 0 PHD-finger Cellulase PF00150.18 ORY88638.1 - 0.023 14.2 2.5 0.1 12.0 0.3 2.1 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.28 ORY88639.1 - 8.4e-59 199.2 0.0 1.4e-58 198.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 ORY88639.1 - 6.9e-41 140.4 0.0 9.6e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 ORY88639.1 - 5.6e-24 84.3 0.3 2.2e-11 44.0 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site CorC_HlyC PF03471.17 ORY88639.1 - 0.044 13.8 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Transporter associated domain F-box-like PF12937.7 ORY88640.1 - 8.7e-06 25.5 0.2 2.2e-05 24.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY88640.1 - 0.00035 20.4 3.3 0.0056 16.5 3.3 2.6 1 1 0 1 1 1 1 F-box domain YccV-like PF08755.11 ORY88640.1 - 0.0089 16.5 0.0 0.03 14.8 0.0 2.0 2 0 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like EKLF_TAD2 PF16833.5 ORY88640.1 - 2.1 8.4 4.8 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Erythroid krueppel-like transcription factor, transactivation 2 DEAD PF00270.29 ORY88641.1 - 5.7e-44 150.0 0.6 1.1e-43 149.0 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY88641.1 - 2.9e-31 108.1 0.2 1.1e-30 106.2 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY88641.1 - 9.5e-05 22.5 0.0 0.00016 21.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY88641.1 - 0.00043 20.6 1.0 0.0029 17.9 0.4 2.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY88641.1 - 0.0032 17.2 0.4 0.0078 15.9 0.4 1.7 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 ORY88641.1 - 0.013 14.8 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 ORY88641.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.14 ORY88641.1 - 0.088 12.8 0.1 0.24 11.4 0.1 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 ORY88641.1 - 0.094 12.2 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain zinc_ribbon_15 PF17032.5 ORY88642.1 - 1.4e-05 25.8 0.1 1.8e-05 25.4 0.1 1.2 1 0 0 1 1 1 1 zinc-ribbon family DUF116 PF01976.17 ORY88642.1 - 0.066 12.7 0.2 0.085 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF116 DZR PF12773.7 ORY88642.1 - 0.13 12.3 2.6 1.4 9.0 2.6 2.0 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 ORY88642.1 - 0.19 12.0 0.5 0.19 12.0 0.5 2.0 2 0 0 2 2 2 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 ORY88642.1 - 2.6 8.1 7.8 5.9 6.9 7.8 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Hamartin PF04388.12 ORY88643.1 - 4.7e-25 88.4 0.4 1.2e-24 87.1 0.4 1.7 1 1 0 1 1 1 1 Hamartin protein Golgin_A5 PF09787.9 ORY88643.1 - 0.0013 18.3 11.0 0.0013 18.3 11.0 2.3 1 1 1 2 2 2 1 Golgin subfamily A member 5 Aminopep PF10023.9 ORY88643.1 - 0.0057 16.1 5.3 0.0085 15.5 5.3 1.3 1 0 0 1 1 1 1 Putative aminopeptidase DUF1664 PF07889.12 ORY88643.1 - 0.069 13.2 3.1 0.12 12.5 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) F-box-like PF12937.7 ORY88644.1 - 5.1e-06 26.3 1.2 1.3e-05 25.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY88644.1 - 6.3e-06 25.9 0.1 4.1e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY88644.1 - 0.0058 16.5 0.0 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 F-box PMT PF02366.18 ORY88645.1 - 7.5e-81 271.3 16.1 7.5e-81 271.3 16.1 2.2 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY88645.1 - 6.4e-51 172.8 12.9 6.4e-51 172.8 12.9 1.9 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY88645.1 - 1.2e-28 100.2 0.3 2e-28 99.5 0.3 1.2 1 0 0 1 1 1 1 MIR domain Wzy_C_2 PF11846.8 ORY88645.1 - 0.05 13.5 0.5 0.17 11.8 0.5 1.9 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Hid1 PF12722.7 ORY88647.1 - 1.8e-120 403.5 0.0 4.3e-120 402.2 0.0 1.6 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 ORY88647.1 - 1.3e-61 208.8 0.0 5.8e-61 206.7 0.0 1.8 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein ATP-synt_Eps PF04627.13 ORY88648.1 - 2.7e-18 65.7 1.4 3.2e-18 65.5 1.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.22 ORY88649.1 - 2.4e-45 154.0 0.0 4.2e-45 153.3 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY88649.1 - 4.7e-30 104.3 0.0 6.5e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY88649.1 - 5.8e-13 48.7 0.0 2.1e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY88649.1 - 0.00026 21.1 0.0 0.00047 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY88649.1 - 0.00033 20.3 0.0 0.00072 19.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY88649.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Dynamin family SRPRB PF09439.10 ORY88649.1 - 0.045 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mcl1_mid PF12341.8 ORY88650.1 - 5.5e-95 318.1 0.0 1.4e-92 310.2 0.0 2.9 2 1 1 3 3 3 2 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 ORY88650.1 - 4.6e-23 81.1 0.7 1e-06 29.3 0.1 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY88650.1 - 2.1e-17 63.2 0.0 0.00039 20.7 0.0 5.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY88650.1 - 3.1e-07 29.7 0.0 0.0065 15.5 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ORY88650.1 - 0.00067 19.5 0.2 2.1 8.4 0.1 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 ORY88650.1 - 0.0033 16.8 0.1 0.27 10.5 0.0 3.0 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal RcsC PF09456.10 ORY88651.1 - 0.087 12.8 0.1 0.5 10.4 0.1 2.3 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) CENP-W PF15510.6 ORY88652.1 - 6.6e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 CENP-W protein F-box-like PF12937.7 ORY88653.1 - 3.6e-07 30.0 1.4 5.3e-07 29.4 0.5 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY88653.1 - 3e-05 23.8 0.3 9.5e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY88653.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 F-box Biotin_lipoyl PF00364.22 ORY88654.1 - 1.3e-19 69.8 0.4 2.4e-19 68.9 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ORY88654.1 - 0.022 14.6 0.1 0.26 11.1 0.0 2.6 2 1 1 3 3 3 0 Biotin-lipoyl like E3_binding PF02817.17 ORY88654.1 - 0.038 14.3 4.1 0.043 14.2 0.1 2.8 2 0 0 2 2 2 0 e3 binding domain OAD_gamma PF04277.13 ORY88654.1 - 1.5 9.5 4.7 15 6.2 0.3 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain TPR_14 PF13428.6 ORY88655.1 - 1.7e-09 37.7 19.2 21 6.3 0.1 11.3 9 2 2 11 11 11 0 Tetratricopeptide repeat Suf PF05843.14 ORY88655.1 - 6.4e-09 36.2 7.5 0.0058 16.6 0.2 6.0 3 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_19 PF14559.6 ORY88655.1 - 0.00013 22.3 2.1 1.9 9.1 0.1 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY88655.1 - 0.00016 21.6 9.7 0.27 11.2 0.3 5.7 4 2 1 5 5 5 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 ORY88655.1 - 0.00031 20.6 17.0 0.5 10.6 0.0 8.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY88655.1 - 0.0016 18.7 9.1 5.7 7.3 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY88655.1 - 0.38 11.2 3.6 2.6e+02 2.4 0.0 5.7 7 1 0 7 7 6 0 Tetratricopeptide repeat DALR_1 PF05746.15 ORY88655.1 - 0.52 10.5 2.0 0.89 9.7 0.0 2.4 3 0 0 3 3 3 0 DALR anticodon binding domain TPR_16 PF13432.6 ORY88655.1 - 1.1 9.9 15.8 14 6.4 0.3 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY88655.1 - 1.7 7.7 16.6 0.86 8.7 0.1 5.8 4 3 1 6 6 6 0 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 ORY88655.1 - 8.1 6.9 16.5 48 4.5 0.0 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY88656.1 - 2.2e-08 33.8 0.1 3.6e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY88656.1 - 7.2e-08 32.1 0.1 1.2e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY88656.1 - 0.00062 19.6 0.2 0.00068 19.5 0.2 1.2 1 0 0 1 1 1 1 F-box CTP_transf_3 PF02348.19 ORY88656.1 - 0.078 12.9 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase Thiolase_N PF00108.23 ORY88657.1 - 6.8e-80 268.2 3.3 6.8e-80 268.2 3.3 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY88657.1 - 1.3e-42 144.3 1.2 2.8e-42 143.3 1.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain Fungal_trans PF04082.18 ORY88658.1 - 1.9e-12 46.8 0.1 3.7e-12 45.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY88658.1 - 3.4e-05 23.9 9.7 5.3e-05 23.3 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T3SS_needle_F PF09392.10 ORY88658.1 - 0.15 12.3 0.4 0.36 11.0 0.4 1.6 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Cyclin PF08613.11 ORY88659.1 - 1.2e-43 149.3 0.6 1.3e-43 149.1 0.6 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY88659.1 - 0.044 13.5 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Cyclin, N-terminal domain Nop16 PF09420.10 ORY88660.1 - 2.1e-55 188.0 5.7 3.6e-55 187.3 5.7 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 CENP-B_dimeris PF09026.10 ORY88660.1 - 0.033 14.6 21.6 0.62 10.5 12.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PPP4R2 PF09184.11 ORY88660.1 - 0.048 13.2 8.3 0.076 12.6 8.3 1.4 1 0 0 1 1 1 0 PPP4R2 Cwf_Cwc_15 PF04889.12 ORY88660.1 - 0.057 13.1 11.8 0.99 9.1 6.3 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 ORY88660.1 - 0.17 11.5 7.7 1.8 8.2 2.8 2.4 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 ORY88660.1 - 0.53 10.5 17.0 4.3 7.6 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) GEN1_C PF18380.1 ORY88660.1 - 2 9.3 9.7 4.7 8.2 3.5 2.6 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain SDA1 PF05285.12 ORY88660.1 - 5 6.4 17.7 5.3 6.4 17.0 1.4 1 1 0 1 1 1 0 SDA1 F-box PF00646.33 ORY88661.1 - 0.00043 20.1 0.0 0.00056 19.7 0.0 1.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY88661.1 - 0.049 13.5 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 F-box-like DHquinase_I PF01487.15 ORY88662.1 - 5.6e-34 118.4 0.0 1.4e-33 117.1 0.0 1.6 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 ORY88662.1 - 3.1e-28 98.9 0.0 5e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase Asparaginase_C PF17763.1 ORY88662.1 - 0.011 15.9 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain AAA_33 PF13671.6 ORY88662.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MAGE_N PF12440.8 ORY88662.1 - 7.2 7.4 7.2 17 6.1 7.2 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Fungal_trans PF04082.18 ORY88663.1 - 4.8e-11 42.2 0.8 6.4e-11 41.8 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY88663.1 - 6.9e-07 29.3 7.7 1e-06 28.7 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4202 PF13875.6 ORY88664.1 - 1.7e-51 174.8 0.0 1.9e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) SE PF08491.10 ORY88665.1 - 1.7e-86 289.7 0.0 3.9e-86 288.5 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 ORY88665.1 - 2.3e-09 37.3 0.1 2.3e-05 24.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY88665.1 - 4.1e-09 36.1 0.1 3.6e-08 33.0 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY88665.1 - 9.1e-05 22.6 0.4 0.00024 21.3 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ORY88665.1 - 0.00012 21.8 0.1 0.00023 20.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 ORY88665.1 - 0.0032 17.4 0.0 0.005 16.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 ORY88665.1 - 0.01 15.1 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY88665.1 - 0.016 14.1 0.3 2.3 6.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 ORY88665.1 - 0.018 14.1 0.5 0.24 10.5 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 ORY88665.1 - 0.027 15.0 0.2 0.068 13.7 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ORY88665.1 - 0.032 14.8 0.1 0.073 13.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORY88665.1 - 0.035 14.3 0.0 0.075 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORY88665.1 - 0.047 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 ORY88665.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 ORY88665.1 - 0.11 11.7 0.0 2.2 7.4 0.2 2.1 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 ORY88665.1 - 0.16 12.2 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 ORY88665.1 - 0.19 11.8 0.0 0.3 11.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 ORY88666.1 - 1.3e-124 416.5 25.1 1.5e-124 416.3 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY88666.1 - 4.6e-23 81.7 33.5 4.6e-23 81.7 33.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily AP_endonuc_2 PF01261.24 ORY88667.1 - 2.8e-20 72.6 0.0 4.5e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF448 PF04296.13 ORY88668.1 - 0.0047 16.7 0.0 0.019 14.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF448) RRG8 PF17068.5 ORY88668.1 - 0.21 10.9 0.3 0.27 10.6 0.3 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial Shikimate_dh_N PF08501.11 ORY88669.1 - 7.6e-23 80.6 0.0 1.4e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 ORY88669.1 - 0.00027 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF615 PF04751.14 ORY88669.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Shikimate_dh_N PF08501.11 ORY88670.1 - 4e-16 59.0 0.0 7.6e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain ABM PF03992.16 ORY88671.1 - 8.1e-07 29.1 0.0 9.4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase MFS_1 PF07690.16 ORY88672.1 - 2.2e-19 69.6 27.0 5.8e-19 68.2 26.9 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Mpp10 PF04006.12 ORY88673.1 - 0.52 8.7 20.4 1 7.7 11.9 2.1 2 0 0 2 2 2 0 Mpp10 protein Cellulase PF00150.18 ORY88674.1 - 4.9e-10 39.3 0.3 9.7e-10 38.3 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RNA_POL_M_15KD PF02150.16 ORY88675.1 - 8.7e-13 47.9 2.9 8.7e-13 47.9 2.9 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 ORY88675.1 - 3.3e-12 46.0 3.4 3.3e-12 46.0 3.4 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1 PF03811.13 ORY88675.1 - 0.018 14.7 2.3 0.018 14.7 2.3 3.1 3 1 0 3 3 3 0 InsA N-terminal domain Zn_Tnp_IS1595 PF12760.7 ORY88675.1 - 0.02 14.9 1.6 0.02 14.9 1.6 2.5 2 2 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 ORY88675.1 - 0.032 14.3 0.4 0.032 14.3 0.4 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-TFIIB PF13453.6 ORY88675.1 - 0.11 11.9 6.4 0.26 10.7 0.7 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger DZR PF12773.7 ORY88675.1 - 0.24 11.5 11.8 0.29 11.2 1.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.6 ORY88675.1 - 0.24 11.8 5.0 0.56 10.6 0.3 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.10 ORY88675.1 - 0.35 11.0 9.5 12 6.1 0.1 3.7 4 0 0 4 4 4 0 Zinc ribbon domain zf_UBZ PF18439.1 ORY88675.1 - 0.75 9.4 9.9 7 6.3 0.1 3.9 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-AN1 PF01428.16 ORY88675.1 - 1.5 9.1 9.8 4.5 7.5 0.3 3.5 3 1 0 3 3 3 0 AN1-like Zinc finger DUF2197 PF09963.9 ORY88675.1 - 1.8 8.9 7.7 0.48 10.7 0.3 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn_ribbon_recom PF13408.6 ORY88675.1 - 1.8 9.1 5.9 0.67 10.5 0.5 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain RecR PF02132.15 ORY88675.1 - 1.9 8.1 0.0 1.9 8.1 0.0 3.5 4 0 0 4 4 4 0 RecR protein DUF3716 PF12511.8 ORY88675.1 - 2.6 8.1 11.4 4.6 7.4 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) Cytochrom_c3_2 PF14537.6 ORY88675.1 - 2.9 8.4 7.9 0.31 11.5 0.6 2.4 1 1 1 2 2 2 0 Cytochrome c3 zf-CHY PF05495.12 ORY88675.1 - 5.3 7.6 12.3 18 5.9 2.1 3.0 1 1 1 2 2 2 0 CHY zinc finger HypA PF01155.19 ORY88675.1 - 5.7 7.0 8.8 3.7 7.6 3.9 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 ORY88675.1 - 9.4 6.3 14.2 1.9 8.5 0.4 3.5 4 0 0 4 4 4 0 zinc-ribbon domain FAD_binding_3 PF01494.19 ORY88676.1 - 2.5e-19 69.7 0.0 3.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY88676.1 - 8.3e-09 35.5 1.7 0.00022 20.9 0.3 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY88676.1 - 1.1e-08 35.2 0.6 5.5e-07 29.7 0.2 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY88676.1 - 3.7e-07 29.7 0.2 0.0001 21.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY88676.1 - 1.2e-05 24.2 0.0 0.0047 15.7 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ORY88676.1 - 4e-05 22.9 0.1 0.00012 21.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ORY88676.1 - 0.0003 20.0 0.2 0.0017 17.5 0.1 2.0 2 1 1 3 3 3 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY88676.1 - 0.00072 20.1 0.0 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY88676.1 - 0.017 14.2 0.2 0.14 11.2 0.2 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 ORY88676.1 - 0.035 13.3 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ORY88676.1 - 0.041 13.2 0.4 0.064 12.6 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY88676.1 - 0.08 12.9 0.3 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 ORY88676.1 - 0.084 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ORY88676.1 - 0.11 11.7 1.7 0.57 9.4 0.2 2.5 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 ORY88676.1 - 0.12 11.6 0.0 0.44 9.7 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 ORY88677.1 - 3.3e-22 78.9 38.4 3.3e-22 78.9 38.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_25 PF13649.6 ORY88679.1 - 1.1e-20 74.2 0.0 1.8e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY88679.1 - 5.6e-19 68.6 0.0 1.8e-18 67.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY88679.1 - 6.3e-17 61.8 0.0 1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY88679.1 - 5.8e-15 55.9 0.0 1.3e-14 54.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY88679.1 - 4.4e-13 49.4 0.0 6.8e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY88679.1 - 1.1e-09 38.0 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ORY88679.1 - 5.7e-08 32.8 0.0 7.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORY88679.1 - 4.3e-07 29.6 0.0 7.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 ORY88679.1 - 1e-06 28.2 0.0 1.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 ORY88679.1 - 5.4e-06 25.7 0.0 8.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TPMT PF05724.11 ORY88679.1 - 1.5e-05 24.8 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 ORY88679.1 - 1.6e-05 24.0 0.0 2.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 ORY88679.1 - 4e-05 23.2 0.3 0.00043 19.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 ORY88679.1 - 0.00011 22.0 0.1 0.0019 17.9 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 ORY88679.1 - 0.00015 21.5 0.0 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 ORY88679.1 - 0.0002 20.9 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.10 ORY88679.1 - 0.00041 19.9 0.0 0.00063 19.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 ORY88679.1 - 0.0007 19.6 0.0 0.001 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 ORY88679.1 - 0.0021 17.1 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DREV PF05219.12 ORY88679.1 - 0.0037 16.4 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_7 PF03492.15 ORY88679.1 - 0.0045 16.2 0.0 1.2 8.3 0.0 2.5 2 1 1 3 3 3 1 SAM dependent carboxyl methyltransferase DOT1 PF08123.13 ORY88679.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltr_RsmB-F PF01189.17 ORY88679.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 ORY88679.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 ORY88679.1 - 0.034 13.8 0.0 0.062 12.9 0.0 1.5 2 0 0 2 2 1 0 Nodulation protein S (NodS) MetW PF07021.12 ORY88679.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF1932 PF09130.11 ORY88679.1 - 0.15 12.1 0.2 0.32 11.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) N6_Mtase PF02384.16 ORY88679.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase SNARE_assoc PF09335.11 ORY88680.1 - 2.3e-08 34.5 6.7 2.3e-08 34.5 6.7 2.8 3 0 0 3 3 3 1 SNARE associated Golgi protein Inositol_P PF00459.25 ORY88681.1 - 7.2e-61 206.1 0.0 1e-60 205.6 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 ORY88682.1 - 2.6e-21 76.0 22.3 4.5e-21 75.2 22.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Chs7 PF12271.8 ORY88684.1 - 7.7e-69 232.2 3.3 8.8e-69 232.0 3.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Lipase_3 PF01764.25 ORY88712.1 - 6.7e-07 29.3 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY88712.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY88712.1 - 0.078 12.5 0.3 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) UPF0227 PF05728.12 ORY88712.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) ERAP1_C PF11838.8 ORY88713.1 - 9e-76 255.4 1.1 1.4e-75 254.8 1.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 ORY88713.1 - 6.3e-67 225.3 0.0 9.2e-66 221.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY88713.1 - 2.9e-36 125.4 0.0 7.2e-33 114.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain FcoT PF10862.8 ORY88713.1 - 0.05 13.2 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 FcoT-like thioesterase domain Glyco_hydro_18 PF00704.28 ORY88714.1 - 2.1e-54 185.3 0.1 3.2e-54 184.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DHC PF09626.10 ORY88714.1 - 0.22 12.4 2.8 2 9.3 3.7 1.9 2 0 0 2 2 2 0 Dihaem cytochrome c SOG2 PF10428.9 ORY88714.1 - 7.2 5.7 23.3 11 5.1 23.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF572 PF04502.13 ORY88714.1 - 8.3 5.9 8.8 11 5.5 8.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ATPase PF06745.13 ORY88715.1 - 0.0044 16.4 0.2 0.0065 15.8 0.2 1.2 1 0 0 1 1 1 1 KaiC DUF1664 PF07889.12 ORY88715.1 - 0.026 14.6 5.7 0.053 13.6 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 ORY88715.1 - 0.026 13.1 2.4 0.029 13.0 2.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cnl2_NKP2 PF09447.10 ORY88715.1 - 0.028 14.6 1.3 0.069 13.3 1.3 1.7 1 0 0 1 1 1 0 Cnl2/NKP2 family protein Pullulanase_Ins PF18494.1 ORY88715.1 - 0.034 14.6 0.2 0.11 13.0 0.2 1.8 1 0 0 1 1 1 0 Pullulanase Ins domain FlaF PF07309.11 ORY88715.1 - 0.074 13.1 1.8 0.098 12.7 0.6 1.8 1 1 1 2 2 2 0 Flagellar protein FlaF DUF4407 PF14362.6 ORY88715.1 - 0.11 11.8 9.2 0.16 11.3 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 ORY88715.1 - 0.14 12.4 3.6 3.8 7.8 0.7 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 ORY88715.1 - 0.15 10.0 2.0 0.2 9.6 2.0 1.2 1 0 0 1 1 1 0 Prominin Syntaxin-6_N PF09177.11 ORY88715.1 - 0.19 12.3 5.3 2.5 8.7 0.1 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MIF4G_like_2 PF09090.11 ORY88715.1 - 0.2 11.1 2.4 0.25 10.8 2.4 1.2 1 0 0 1 1 1 0 MIF4G like DUF4803 PF16061.5 ORY88715.1 - 0.32 10.4 1.0 0.42 10.0 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) KfrA_N PF11740.8 ORY88715.1 - 0.4 11.4 12.5 0.19 12.4 9.0 1.9 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Histone_HNS PF00816.21 ORY88715.1 - 0.51 11.2 8.2 0.89 10.4 1.0 2.2 2 0 0 2 2 2 0 H-NS histone family HALZ PF02183.18 ORY88715.1 - 1.4 9.2 7.8 2.4 8.5 0.9 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Enkurin PF13864.6 ORY88715.1 - 2 8.9 14.3 6.8 7.2 3.0 3.0 1 1 1 2 2 2 0 Calmodulin-binding DUF737 PF05300.11 ORY88715.1 - 2.3 8.5 11.5 1.7 9.0 10.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) DUF2203 PF09969.9 ORY88715.1 - 2.4 8.9 8.1 6 7.6 6.5 2.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) M PF02370.16 ORY88715.1 - 3.7 8.4 8.7 11 7.0 0.2 3.7 3 0 0 3 3 3 0 M protein repeat Fzo_mitofusin PF04799.13 ORY88715.1 - 4.4 6.8 6.0 12 5.5 0.5 2.9 2 1 1 3 3 3 0 fzo-like conserved region DUF4337 PF14235.6 ORY88715.1 - 5 7.2 7.7 54 3.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) COG4 PF08318.12 ORY88716.1 - 4.6e-76 256.1 0.0 1.6e-75 254.3 0.0 1.8 2 0 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 ORY88716.1 - 0.033 13.1 0.2 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 RINT-1 / TIP-1 family DUF948 PF06103.11 ORY88716.1 - 0.071 13.4 1.0 0.18 12.1 1.0 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 ORY88716.1 - 0.2 10.5 1.8 0.3 9.9 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IFT57 PF10498.9 ORY88716.1 - 0.24 10.3 0.6 0.36 9.7 0.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 ORY88716.1 - 0.32 11.1 1.8 0.71 9.9 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PNK3P PF08645.11 ORY88717.1 - 3.4e-51 173.1 0.0 5.6e-51 172.5 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 ORY88717.1 - 2.6e-12 47.1 0.0 8.5e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY88717.1 - 0.0014 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 ORY88717.1 - 0.11 12.0 0.4 6.1 6.2 0.0 2.1 1 1 1 2 2 2 0 Chromatin associated protein KTI12 SRPRB PF09439.10 ORY88717.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PGK PF00162.19 ORY88718.1 - 8.6e-149 495.6 1.7 9.8e-149 495.4 1.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 ORY88718.1 - 0.055 13.5 1.2 0.27 11.3 0.0 2.6 3 0 0 3 3 3 0 PA domain PrpR_N PF06506.11 ORY88718.1 - 0.087 12.4 0.7 8.5 5.9 0.1 2.8 2 1 0 2 2 2 0 Propionate catabolism activator DUF4201 PF13870.6 ORY88719.1 - 0.055 13.2 10.4 0.023 14.5 6.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF501 PF04417.12 ORY88719.1 - 2.9 7.7 6.4 0.86 9.4 2.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF501) VSG_B PF13206.6 ORY88719.1 - 3.7 6.7 7.2 0.14 11.3 1.8 1.4 2 0 0 2 2 2 0 Trypanosomal VSG domain AAA_13 PF13166.6 ORY88719.1 - 4 6.0 7.7 3.9 6.0 6.9 1.4 1 1 0 1 1 1 0 AAA domain SKA1 PF07160.12 ORY88719.1 - 4.8 7.0 8.0 1.6 8.6 4.7 1.9 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DivIC PF04977.15 ORY88719.1 - 5 7.0 18.8 12 5.7 0.0 4.3 5 0 0 5 5 5 0 Septum formation initiator Seryl_tRNA_N PF02403.22 ORY88719.1 - 6.8 7.0 9.9 1.5 9.1 2.5 3.0 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Thiolase_N PF00108.23 ORY88721.1 - 1.4e-61 208.2 0.1 3.9e-61 206.7 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY88721.1 - 5e-43 145.6 0.2 1.2e-42 144.4 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 ORY88721.1 - 0.011 15.9 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 ORY88721.1 - 0.027 14.1 0.0 0.088 12.4 0.0 1.9 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Stig1 PF04885.13 ORY88722.1 - 1.2e-06 29.0 106.5 0.24 11.9 7.4 9.5 2 1 5 9 9 9 8 Stigma-specific protein, Stig1 Adaptin_N PF01602.20 ORY88723.1 - 2e-93 313.7 0.0 2.7e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY88723.1 - 3.2e-12 46.8 0.1 2.5e-06 27.6 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY88723.1 - 0.0075 16.4 7.0 18 5.9 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat Tti2 PF10521.9 ORY88723.1 - 0.019 14.5 0.1 4 6.9 0.0 2.5 1 1 1 2 2 2 0 Tti2 family HEAT_2 PF13646.6 ORY88723.1 - 0.029 14.8 11.1 0.63 10.5 0.6 5.2 4 1 1 5 5 5 0 HEAT repeats ERG4_ERG24 PF01222.17 ORY88724.1 - 2.2e-120 402.3 12.0 2.9e-120 402.0 12.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Acetyltransf_1 PF00583.25 ORY88725.1 - 0.00054 20.2 0.3 0.0099 16.1 0.0 2.2 1 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 ORY88725.1 - 0.024 15.3 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY88725.1 - 0.054 13.9 0.1 0.14 12.6 0.1 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pex19 PF04614.12 ORY88728.1 - 1.2e-55 189.0 0.4 1.2e-55 189.0 0.4 1.9 2 1 0 2 2 2 1 Pex19 protein family SRP54_N PF02881.19 ORY88728.1 - 0.045 14.0 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain GET2 PF08690.10 ORY88728.1 - 0.37 10.4 12.0 0.71 9.5 2.4 2.3 1 1 1 2 2 2 0 GET complex subunit GET2 DUF935 PF06074.12 ORY88728.1 - 4.7 5.8 7.6 5.1 5.7 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF935) ERG4_ERG24 PF01222.17 ORY88729.1 - 7.4e-117 390.7 12.7 9.7e-117 390.3 12.7 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF983 PF06170.12 ORY88729.1 - 8 6.9 8.2 2.1 8.8 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF983) CK_II_beta PF01214.18 ORY88730.1 - 7.9e-80 267.0 0.0 9.3e-80 266.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Na_Ca_ex PF01699.24 ORY88731.1 - 1.5e-41 141.8 40.3 1.4e-20 73.8 12.5 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UPF0060 PF02694.15 ORY88731.1 - 0.066 13.4 7.6 0.15 12.3 4.9 2.9 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family Mito_carr PF00153.27 ORY88732.1 - 2.9e-56 187.4 3.9 2.7e-19 68.9 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 ORY88732.1 - 2.1 8.8 6.7 5.7 7.3 0.2 3.3 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family PPR_2 PF13041.6 ORY88735.1 - 0.0099 16.0 0.0 0.16 12.2 0.0 2.5 1 1 1 2 2 2 2 PPR repeat family PPR_3 PF13812.6 ORY88735.1 - 0.061 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Pentatricopeptide repeat domain DNA_binding_1 PF01035.20 ORY88736.1 - 5.8e-25 87.2 0.0 1e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain AAA_12 PF13087.6 ORY88737.1 - 2e-34 119.0 0.0 2.9e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY88737.1 - 9.9e-22 78.0 2.6 1.4e-12 48.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY88737.1 - 9.6e-10 38.5 0.0 1.5e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 ORY88737.1 - 1.9e-07 30.9 0.0 1.3e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ORY88737.1 - 4.1e-06 27.2 0.0 8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY88737.1 - 0.00066 19.7 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY88737.1 - 0.0037 17.5 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY88737.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 ORY88737.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein UvrD_C PF13361.6 ORY88737.1 - 0.018 14.4 0.0 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 ORY88737.1 - 0.026 14.4 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 Helicase AAA_16 PF13191.6 ORY88737.1 - 0.028 14.8 0.0 0.065 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 ORY88737.1 - 0.044 13.0 0.0 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase AAA PF00004.29 ORY88737.1 - 0.058 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) YAcAr PF10686.9 ORY88737.1 - 0.059 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Viral_helicase1 PF01443.18 ORY88737.1 - 0.1 12.3 0.1 5.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 ORY88737.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORY88737.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DEAD PF00270.29 ORY88737.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mg_chelatase PF01078.21 ORY88737.1 - 0.17 11.3 0.0 0.45 9.9 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI LSDAT_euk PF18139.1 ORY88737.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM S-methyl_trans PF02574.16 ORY88738.1 - 4.3e-38 131.6 0.0 8.3e-38 130.7 0.0 1.4 1 1 0 1 1 1 1 Homocysteine S-methyltransferase UCR_hinge PF02320.16 ORY88739.1 - 7.8e-27 93.3 7.1 1.5e-26 92.4 7.1 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF2052 PF09747.9 ORY88739.1 - 0.11 12.6 7.1 0.12 12.5 7.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) MAS20 PF02064.15 ORY88739.1 - 0.26 11.4 4.3 0.36 10.9 4.3 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor CENP-B_dimeris PF09026.10 ORY88739.1 - 0.3 11.5 12.5 0.32 11.4 12.1 1.3 1 1 0 1 1 1 0 Centromere protein B dimerisation domain PTPRCAP PF15713.5 ORY88739.1 - 0.89 9.8 10.6 1.1 9.5 10.6 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TRAP_alpha PF03896.16 ORY88739.1 - 1.1 8.5 3.3 1.1 8.4 3.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 ORY88739.1 - 1.2 7.1 8.2 1.3 7.1 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_25 PF13649.6 ORY88741.1 - 8.3e-09 36.0 0.0 1.9e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY88741.1 - 1.3e-07 32.2 0.0 3.6e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY88741.1 - 2.6e-05 24.1 0.0 5.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY88741.1 - 0.00075 20.2 0.0 0.0022 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY88741.1 - 0.0026 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAS PF03059.16 ORY88741.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein Zn_clus PF00172.18 ORY88742.1 - 4.8e-06 26.6 8.3 8.5e-06 25.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_US12 PF05363.12 ORY88742.1 - 0.18 12.6 1.8 0.32 11.8 1.8 1.4 1 0 0 1 1 1 0 Herpesvirus US12 family DUF2207 PF09972.9 ORY88743.1 - 0.056 12.2 0.0 0.056 12.2 0.0 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) GDP_Man_Dehyd PF16363.5 ORY88744.1 - 2.8e-43 148.6 0.0 5.3e-43 147.7 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY88744.1 - 7.3e-41 140.2 0.0 1.2e-40 139.4 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY88744.1 - 5.8e-13 48.6 0.1 7.1e-12 45.1 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY88744.1 - 2e-11 43.6 0.1 7.2e-11 41.7 0.1 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY88744.1 - 6.2e-11 41.8 0.0 1.7e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 ORY88744.1 - 7.7e-08 32.5 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 ORY88744.1 - 0.0011 18.3 0.0 0.003 16.8 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ORY88744.1 - 0.0014 18.5 0.1 0.0039 17.1 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 ORY88744.1 - 0.0025 17.3 0.3 0.049 13.1 0.3 2.1 1 1 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 ORY88744.1 - 0.028 14.3 0.0 0.1 12.5 0.0 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ORY88744.1 - 0.056 13.0 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.19 ORY88745.1 - 2.5e-07 30.3 0.0 1.4e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Dak1 PF02733.17 ORY88746.1 - 2.3e-101 338.8 0.2 3.7e-101 338.1 0.2 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ORY88746.1 - 1.4e-34 119.5 9.6 1.4e-34 119.5 9.6 1.9 2 0 0 2 2 2 1 DAK2 domain PHD PF00628.29 ORY88748.1 - 8.1e-10 38.4 5.9 1.2e-09 37.9 5.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY88748.1 - 0.00024 20.6 2.2 0.00039 19.9 2.2 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 ORY88748.1 - 0.052 13.6 1.1 0.11 12.5 1.1 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger SET PF00856.28 ORY88748.1 - 0.12 12.8 0.0 1.8 8.9 0.0 2.2 1 1 0 1 1 1 0 SET domain Elong_Iki1 PF10483.9 ORY88749.1 - 2.1e-16 60.3 0.1 4.6e-11 42.8 0.2 2.1 2 0 0 2 2 2 2 Elongator subunit Iki1 FAD_binding_3 PF01494.19 ORY88750.1 - 1.8e-09 37.3 0.0 2.9e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY88750.1 - 0.062 13.3 0.4 0.42 10.6 0.0 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY88751.1 - 2.3e-08 33.7 0.2 2.6e-08 33.5 0.2 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY88751.1 - 0.00099 18.4 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY88751.1 - 0.0017 18.9 0.1 0.0045 17.5 0.1 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY88751.1 - 0.006 16.8 0.1 0.0093 16.2 0.1 1.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 ORY88751.1 - 0.0064 16.1 0.1 0.0085 15.7 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 ORY88751.1 - 0.0074 15.9 0.3 0.0076 15.9 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY88751.1 - 0.038 13.1 0.5 0.057 12.5 0.4 1.3 1 1 0 1 1 1 0 FAD binding domain ThiF PF00899.21 ORY88751.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 ORY88752.1 - 1e-18 67.8 0.0 1.8e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY88752.1 - 2e-07 30.6 0.0 5.8e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY88752.1 - 1.6e-06 27.5 0.9 2.4e-06 26.9 0.9 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY88752.1 - 4.3e-06 26.9 1.2 1.2e-05 25.4 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY88752.1 - 7.7e-06 25.7 4.4 0.00017 21.3 4.9 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY88752.1 - 0.00016 20.9 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORY88752.1 - 0.0003 20.3 0.8 0.00043 19.8 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY88752.1 - 0.00041 20.9 0.2 0.0011 19.5 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY88752.1 - 0.00088 18.1 0.2 0.0071 15.1 0.3 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 ORY88752.1 - 0.0094 15.2 2.1 0.017 14.3 2.0 1.4 1 1 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 ORY88752.1 - 0.026 13.8 0.1 0.056 12.7 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY88752.1 - 0.049 13.6 0.2 0.84 9.6 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amino_oxidase PF01593.24 ORY88752.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ORY88752.1 - 0.079 12.0 0.3 0.17 10.9 0.3 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 ORY88752.1 - 0.3 10.6 0.3 0.52 9.9 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Carn_acyltransf PF00755.20 ORY88754.1 - 2.3e-168 561.5 0.0 2.6e-168 561.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF5519 PF17648.1 ORY88754.1 - 0.00045 20.1 0.6 0.0013 18.6 0.3 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5519) Peptidase_M76 PF09768.9 ORY88755.1 - 2.4e-63 212.9 0.0 3.1e-63 212.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Fip1 PF05182.13 ORY88756.1 - 9.4e-21 73.1 0.8 1.6e-20 72.3 0.8 1.4 1 0 0 1 1 1 1 Fip1 motif Borrelia_lipo_1 PF05714.11 ORY88757.1 - 0.034 13.9 5.9 0.043 13.6 5.2 1.4 1 1 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein RR_TM4-6 PF06459.12 ORY88757.1 - 0.35 10.6 10.3 0.028 14.3 5.6 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Fib_alpha PF08702.10 ORY88757.1 - 0.37 11.0 5.3 0.48 10.6 3.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 ORY88757.1 - 2.4 8.5 5.7 8.1 6.8 3.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 ORY88757.1 - 3.8 5.3 8.6 5.4 4.8 8.6 1.4 1 1 0 1 1 1 0 Prominin LMBR1 PF04791.16 ORY88757.1 - 7.1 5.4 4.9 8.6 5.1 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein V-ATPase_G_2 PF16999.5 ORY88757.1 - 7.7 7.0 18.9 10 6.6 0.1 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit IDO PF01231.18 ORY88758.1 - 1.9e-31 109.3 0.0 2.9e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase PIG-F PF06699.11 ORY88759.1 - 2.2e-40 138.7 0.8 4e-40 137.9 0.8 1.4 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Glyco_hydro_47 PF01532.20 ORY88760.1 - 4.4e-149 497.3 0.0 5.1e-149 497.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 UBN_AB PF14075.6 ORY88761.1 - 7.9e-26 91.1 0.0 7.9e-26 91.1 0.0 2.1 3 0 0 3 3 3 1 Ubinuclein conserved middle domain HUN PF08729.10 ORY88761.1 - 2.1e-10 40.5 0.0 5.8e-10 39.0 0.0 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain WD40 PF00400.32 ORY88762.1 - 1.2e-15 57.5 2.9 3e-05 24.7 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.8 ORY88762.1 - 1.7 7.2 4.7 10 4.6 0.2 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DIM1 PF02966.16 ORY88763.1 - 1.9e-65 218.6 0.0 2.1e-65 218.5 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 ORY88763.1 - 0.0052 16.7 0.1 0.0069 16.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY88763.1 - 0.034 14.5 0.0 0.057 13.8 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like F-box-like PF12937.7 ORY88764.1 - 0.0087 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like N_BRCA1_IG PF16158.5 ORY88766.1 - 6.9e-27 94.2 0.0 2.3e-26 92.5 0.0 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 ORY88766.1 - 1.9e-23 82.0 30.9 1e-08 34.8 5.0 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 ORY88766.1 - 0.0027 18.0 13.1 0.01 16.2 0.8 4.1 4 0 0 4 4 4 2 C1 domain AOC_like PF18678.1 ORY88766.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain LTXXQ PF07813.12 ORY88766.1 - 4.6 8.0 9.7 1.6 9.5 1.0 2.7 2 0 0 2 2 2 0 LTXXQ motif family protein Mito_carr PF00153.27 ORY88767.1 - 4.9e-39 132.2 5.8 1.7e-15 56.7 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF962 PF06127.11 ORY88768.1 - 5.6e-26 90.5 0.2 1.4e-25 89.2 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Scramblase PF03803.15 ORY88769.1 - 3.1e-50 170.5 0.0 4.3e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Scramblase SSP160 PF06933.11 ORY88769.1 - 5 5.2 14.7 5.7 5.0 13.0 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 F-box-like PF12937.7 ORY88770.1 - 0.031 14.1 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 F-box-like Fungus-induced PF10917.8 ORY88771.1 - 0.27 11.6 2.2 0.42 11.0 2.2 1.3 1 0 0 1 1 1 0 Fungus-induced protein Pkinase PF00069.25 ORY88772.1 - 4.4e-34 118.0 0.0 1.2e-20 74.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88772.1 - 5.7e-10 38.9 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY88772.1 - 4.2e-05 23.0 0.0 0.00098 18.5 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 ORY88772.1 - 0.00076 19.5 4.0 0.011 15.7 0.5 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY88772.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY88772.1 - 0.057 12.2 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ZapB PF06005.12 ORY88773.1 - 0.017 15.6 2.1 0.029 14.8 2.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB GATase PF00117.28 ORY88775.1 - 5.2e-36 124.2 0.0 8.5e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 ORY88775.1 - 1.4e-30 105.2 0.0 3.2e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 ORY88775.1 - 5.6e-11 42.0 0.2 5.1e-07 29.1 0.1 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 ORY88775.1 - 1.7e-07 31.2 0.0 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 ORY88775.1 - 0.00012 21.0 0.1 0.00022 20.1 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 ORY88775.1 - 0.0032 17.0 0.0 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 ORY88775.1 - 0.0046 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 ORY88775.1 - 0.017 14.8 0.2 0.041 13.6 0.0 1.7 2 0 0 2 2 2 0 PP-loop family Arginosuc_synth PF00764.19 ORY88775.1 - 0.027 13.7 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase HOASN PF14515.6 ORY88775.1 - 0.1 13.0 0.2 0.23 11.9 0.2 1.5 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Zn_clus PF00172.18 ORY88776.1 - 1.6e-06 28.1 9.7 2.6e-06 27.5 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2470 PF10615.9 ORY88777.1 - 4.7e-15 56.0 0.0 7.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Macoilin PF09726.9 ORY88778.1 - 0.018 13.6 5.8 0.019 13.6 5.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 ORY88778.1 - 1 8.1 8.9 1.2 7.9 8.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.9 ORY88778.1 - 1.3 8.6 39.6 1.1 8.8 17.1 2.4 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein GREB1 PF15782.5 ORY88778.1 - 1.9 5.5 5.1 2.5 5.1 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 ORY88778.1 - 3.3 6.4 4.3 4.1 6.1 4.3 1.3 1 0 0 1 1 1 0 Presenilin DUF3391 PF11871.8 ORY88778.1 - 4.9 7.7 6.8 5.9 7.4 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Med3 PF11593.8 ORY88778.1 - 9.5 5.3 6.9 16 4.5 6.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Thaumatin PF00314.17 ORY88779.1 - 6.3e-57 192.6 11.3 1.4e-32 113.1 6.7 2.2 2 0 0 2 2 2 2 Thaumatin family TMEM154 PF15102.6 ORY88779.1 - 0.055 13.4 0.2 0.12 12.3 0.2 1.6 1 1 0 1 1 1 0 TMEM154 protein family SOG2 PF10428.9 ORY88779.1 - 3.5 6.7 5.3 4.5 6.4 5.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Thaumatin PF00314.17 ORY88780.1 - 8.7e-48 162.8 6.0 1e-47 162.5 6.0 1.1 1 0 0 1 1 1 1 Thaumatin family Gly-zipper_YMGG PF13441.6 ORY88781.1 - 2.9e-05 23.7 16.0 2.9e-05 23.7 16.0 6.9 6 1 0 6 6 6 3 YMGG-like Gly-zipper Spt20 PF12090.8 ORY88781.1 - 5.2 6.6 11.7 13 5.3 11.7 1.6 1 0 0 1 1 1 0 Spt20 family MPC PF03650.13 ORY88782.1 - 1.9e-39 134.2 0.4 2.2e-39 134.0 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers F-box-like PF12937.7 ORY88783.1 - 0.0012 18.6 0.0 0.0043 16.9 0.0 1.9 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 ORY88783.1 - 3.1 7.6 7.5 27 4.6 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat TauD PF02668.16 ORY88784.1 - 9.1e-43 147.0 0.0 1.3e-42 146.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FPN1 PF06963.12 ORY88785.1 - 1.6e-126 422.4 10.2 1.8e-126 422.2 10.2 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) adh_short PF00106.25 ORY88786.1 - 2e-27 95.9 0.0 6.6e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88786.1 - 1.3e-16 60.8 0.0 6.7e-15 55.3 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY88786.1 - 9e-08 32.2 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY88786.1 - 1.5e-05 24.6 0.0 1.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY88786.1 - 0.0039 16.6 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Peripla_BP_4 PF13407.6 ORY88786.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Polysacc_synt_2 PF02719.15 ORY88786.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 ORY88786.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Oxidored_nitro PF00148.19 ORY88786.1 - 0.14 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Rap_GAP PF02145.15 ORY88788.1 - 3.2e-45 154.0 0.0 5.1e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 ORY88788.1 - 2.5e-39 135.4 0.0 5.8e-33 114.5 0.0 2.8 2 1 0 2 2 2 2 Tuberin DUF3384 PF11864.8 ORY88788.1 - 8.7e-24 84.2 0.0 2.5e-17 62.9 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3384) Velvet PF11754.8 ORY88789.1 - 1.3e-47 162.9 2.7 6.1e-31 108.2 0.5 3.7 2 2 1 3 3 3 2 Velvet factor SPT2 PF08243.11 ORY88790.1 - 3.8e-18 66.0 15.2 3.8e-18 66.0 15.2 4.1 4 1 0 4 4 4 1 SPT2 chromatin protein V-SNARE PF05008.15 ORY88791.1 - 6.6e-17 61.7 2.9 6.6e-17 61.7 2.9 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORY88791.1 - 7e-16 58.3 7.7 2.3e-15 56.6 0.7 3.0 2 1 1 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY88791.1 - 0.036 14.0 3.1 0.05 13.5 0.2 2.6 1 1 2 3 3 3 0 Sec20 MAT1 PF06391.13 ORY88791.1 - 1.1 9.1 6.0 0.34 10.7 2.5 1.8 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 G-patch PF01585.23 ORY88792.1 - 1e-08 34.9 0.0 3.3e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 G-patch domain EphA2_TM PF14575.6 ORY88792.1 - 0.3 12.0 2.0 0.67 10.9 2.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.7 ORY88793.1 - 0.00016 21.5 1.2 0.002 18.0 1.2 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 ORY88793.1 - 2.9 7.9 5.6 13 5.8 0.4 2.7 2 0 0 2 2 2 0 F-box domain DUF4173 PF13777.6 ORY88794.1 - 1 8.8 6.2 2.2 7.6 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) SH3_12 PF18129.1 ORY88795.1 - 6.6e-22 77.4 1.1 1.3e-21 76.5 1.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 ORY88795.1 - 6.3e-06 26.2 0.1 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF3908 PF13048.6 ORY88795.1 - 0.12 12.6 0.2 20 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3908) Mannosyl_trans3 PF11051.8 ORY88796.1 - 1.1e-34 120.1 0.0 1.5e-23 83.5 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 ORY88796.1 - 0.07 12.7 0.1 0.18 11.3 0.1 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 8 DUF4303 PF14136.6 ORY88796.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) GSHPx PF00255.19 ORY88797.1 - 1.2e-39 134.2 0.4 1.6e-39 133.8 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY88797.1 - 0.00016 21.6 0.1 0.00033 20.6 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY88797.1 - 0.0048 16.6 0.1 0.0072 16.1 0.1 1.3 1 0 0 1 1 1 1 Redoxin DUF4174 PF13778.6 ORY88797.1 - 0.081 13.4 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) UCH PF00443.29 ORY88798.1 - 6.7e-40 137.2 0.0 1e-39 136.6 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY88798.1 - 2.9e-08 33.7 0.2 0.00029 20.5 0.0 3.1 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase OrsD PF12013.8 ORY88798.1 - 0.091 13.2 0.6 2.2 8.8 0.1 2.9 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D NAM-associated PF14303.6 ORY88798.1 - 0.21 12.3 7.2 2.9e+02 2.1 0.0 3.9 3 1 0 3 3 3 0 No apical meristem-associated C-terminal domain DNA_pol_phi PF04931.13 ORY88798.1 - 0.24 9.5 7.9 0.37 8.9 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Trehalase PF01204.18 ORY88799.1 - 1.6e-156 522.1 0.0 2.5e-156 521.5 0.0 1.3 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 ORY88799.1 - 8e-16 57.5 0.0 1.6e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Dynamin_N PF00350.23 ORY88800.1 - 3.2e-40 137.9 0.0 6.9e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ORY88800.1 - 1.9e-07 30.6 0.0 1.3e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 ORY88800.1 - 5.4e-05 23.3 0.0 0.00016 21.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY88800.1 - 0.035 13.9 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY88800.1 - 0.07 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain Lon_C PF05362.13 ORY88801.1 - 1.7e-64 217.2 0.3 2.8e-64 216.4 0.3 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORY88801.1 - 2e-34 119.3 0.0 4.7e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORY88801.1 - 8.7e-23 81.2 0.0 3.4e-22 79.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 ORY88801.1 - 7.7e-06 25.8 0.1 2.6e-05 24.0 0.1 2.0 2 1 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 ORY88801.1 - 1.5e-05 25.2 0.0 4.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORY88801.1 - 1.9e-05 24.7 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 ORY88801.1 - 4e-05 22.7 0.0 8.1e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 ORY88801.1 - 0.00043 20.1 0.0 0.0017 18.1 0.0 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY88801.1 - 0.0013 19.0 0.0 0.032 14.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY88801.1 - 0.002 18.6 0.1 0.012 16.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ORY88801.1 - 0.015 15.3 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY88801.1 - 0.019 14.7 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ORY88801.1 - 0.042 13.8 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 ORY88801.1 - 0.059 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 ORY88801.1 - 0.07 13.3 0.1 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase AAA_30 PF13604.6 ORY88801.1 - 0.088 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY88801.1 - 0.089 13.3 0.0 0.089 13.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 ORY88801.1 - 0.1 12.1 0.5 0.39 10.2 0.0 2.1 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF908 PF06012.12 ORY88801.1 - 3.6 6.9 8.6 15 4.9 3.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) CmlA_N PF18456.1 ORY88802.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Diiron non-heme beta-hydroxylase N-terminal domain Pkinase PF00069.25 ORY88803.1 - 3.8e-59 200.2 0.0 5.2e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88803.1 - 3.1e-31 108.6 0.0 4.4e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY88803.1 - 8.9e-10 38.4 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY88803.1 - 9.5e-05 21.8 0.1 0.00021 20.7 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY88803.1 - 0.00015 20.7 0.0 0.00024 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY88803.1 - 0.00089 19.2 0.2 0.0018 18.2 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY88803.1 - 0.017 14.1 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 ORY88803.1 - 0.025 14.2 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY88803.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Peroxidase_2 PF01328.17 ORY88804.1 - 3.3e-34 119.0 0.0 4.5e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Apt1 PF10351.9 ORY88805.1 - 0.054 12.3 1.6 0.059 12.2 1.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 ORY88805.1 - 0.13 12.1 4.7 0.17 11.8 4.7 1.1 1 0 0 1 1 1 0 SPX domain PAP1 PF08601.10 ORY88805.1 - 5.9 6.5 13.1 8.1 6.1 13.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Chitin_synth_2 PF03142.15 ORY88806.1 - 4.4e-232 771.4 0.4 5.8e-232 771.0 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY88806.1 - 1.1e-102 344.5 0.0 4.2e-94 316.1 0.0 2.1 2 0 0 2 2 2 2 Myosin head (motor domain) DEK_C PF08766.11 ORY88806.1 - 5.7e-15 55.0 0.0 1.9e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 ORY88806.1 - 1.8e-13 50.9 0.0 6.1e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORY88806.1 - 4.5e-13 49.1 0.2 8.8e-09 35.4 0.0 3.5 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 ORY88806.1 - 8.9e-13 48.6 2.6 2.4e-12 47.2 1.5 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY88806.1 - 1.1e-05 25.3 0.1 0.011 15.5 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY88806.1 - 0.0027 17.2 0.1 0.047 13.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.6 ORY88806.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY88806.1 - 0.081 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 ORY88806.1 - 0.1 13.0 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 ORY88806.1 - 0.19 11.8 0.1 0.38 10.8 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Exo84_C PF16528.5 ORY88807.1 - 6.1e-57 192.8 0.0 9.5e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Exocyst component 84 C-terminal Peptidase_M16 PF00675.20 ORY88807.1 - 2.8e-21 76.0 0.1 6e-21 75.0 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Vps51 PF08700.11 ORY88807.1 - 3e-10 40.0 0.0 1.1e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 Peptidase_M16_C PF05193.21 ORY88807.1 - 1.1e-08 35.4 0.0 3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain COG2 PF06148.11 ORY88807.1 - 1e-05 25.6 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.16 ORY88808.1 - 4.5e-41 141.0 48.3 2.5e-38 131.9 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY88808.1 - 8.3e-10 38.1 7.1 8.3e-10 38.1 7.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORY88808.1 - 1.4e-06 27.0 2.8 1.4e-06 27.0 2.8 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2045 PF09741.9 ORY88808.1 - 0.27 10.6 0.0 0.43 9.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) Peroxidase_2 PF01328.17 ORY88809.1 - 4.4e-34 118.7 0.0 5.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 GDP_Man_Dehyd PF16363.5 ORY88810.1 - 1.1e-158 527.9 0.0 1.3e-158 527.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY88810.1 - 4.7e-73 245.6 0.0 6.3e-73 245.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY88810.1 - 3.4e-06 26.4 0.0 6.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 ORY88810.1 - 9.9e-05 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY88810.1 - 0.00031 20.0 0.0 0.00074 18.7 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 ORY88810.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding SnoaL_2 PF12680.7 ORY88811.1 - 6.4e-07 30.0 0.0 8.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 ORY88811.1 - 0.00061 19.9 0.0 0.0009 19.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain TauD PF02668.16 ORY88812.1 - 3.5e-46 158.2 0.2 4.2e-46 157.9 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.24 ORY88813.1 - 5e-82 276.2 20.1 5.9e-82 275.9 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY88813.1 - 7.5e-21 74.4 23.3 7.5e-21 74.4 23.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.24 ORY88814.1 - 9.6e-33 113.5 0.8 1.6e-32 112.8 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY88814.1 - 1e-20 73.6 0.0 2.3e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY88814.1 - 2.7e-13 49.9 0.1 5.4e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY88814.1 - 3.7e-12 46.9 1.0 5e-11 43.2 1.0 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY88814.1 - 4.2e-07 30.3 0.1 1.2e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Pro_isomerase PF00160.21 ORY88815.1 - 9.7e-44 149.4 0.2 1.2e-43 149.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FTR1 PF03239.14 ORY88816.1 - 5e-67 226.2 6.1 5.9e-67 226.0 6.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Tmemb_161AB PF10268.9 ORY88816.1 - 0.014 14.0 0.1 0.024 13.3 0.1 1.3 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Yip1 PF04893.17 ORY88816.1 - 0.13 12.0 18.1 0.22 11.2 1.4 3.4 4 0 0 4 4 4 0 Yip1 domain DUF2070 PF09843.9 ORY88816.1 - 2.1 6.5 4.9 1.5 7.1 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) S_4TM PF18159.1 ORY88816.1 - 6.2 6.0 7.6 0.95 8.7 0.8 2.5 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain FTR1 PF03239.14 ORY88817.1 - 1.4e-62 211.6 6.8 2e-62 211.1 6.8 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family Phage_holin_3_6 PF07332.11 ORY88817.1 - 0.0017 18.3 1.4 0.0017 18.3 1.4 2.9 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2721 PF11026.8 ORY88817.1 - 0.014 15.3 1.3 0.014 15.3 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Nucleos_tra2_C PF07662.13 ORY88817.1 - 0.068 13.0 3.6 0.7 9.7 0.2 2.5 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus Synaptobrevin PF00957.21 ORY88817.1 - 0.069 13.0 0.7 0.23 11.3 0.1 2.3 2 0 0 2 2 2 0 Synaptobrevin GWT1 PF06423.12 ORY88817.1 - 0.12 12.5 1.5 1.2 9.2 0.2 3.1 3 1 0 3 3 3 0 GWT1 Yip1 PF04893.17 ORY88817.1 - 0.45 10.2 21.3 0.1 12.3 1.0 3.2 3 0 0 3 3 3 0 Yip1 domain NiFe_hyd_3_EhaA PF17367.2 ORY88817.1 - 0.59 10.3 6.3 2.8 8.1 0.2 3.0 2 1 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A MgtE PF01769.16 ORY88817.1 - 3.8 7.9 15.3 0.52 10.7 0.7 3.1 3 0 0 3 3 3 0 Divalent cation transporter DUF456 PF04306.13 ORY88817.1 - 9.5 6.5 18.3 1.7 9.0 3.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF456) FTR1 PF03239.14 ORY88818.1 - 1.5e-63 214.8 8.5 1.9e-63 214.4 8.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2721 PF11026.8 ORY88818.1 - 0.015 15.1 1.4 0.015 15.1 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Nucleos_tra2_C PF07662.13 ORY88818.1 - 0.039 13.8 4.0 0.7 9.7 0.2 2.5 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus GWT1 PF06423.12 ORY88818.1 - 0.51 10.5 3.6 2.2 8.4 0.9 3.1 3 1 0 3 3 3 0 GWT1 Claudin_2 PF13903.6 ORY88818.1 - 0.86 9.3 13.3 2 8.2 2.8 2.9 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction RseC_MucC PF04246.12 ORY88818.1 - 3 7.8 10.5 6.8 6.7 0.6 3.3 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC tRNA-synt_2b PF00587.25 ORY88820.1 - 2.8e-35 121.9 0.0 4.4e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY88820.1 - 8.7e-19 67.5 0.1 1.7e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 ORY88820.1 - 9.9e-12 44.8 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 ORY88820.1 - 1.5e-11 44.1 0.0 3.6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain TatD_DNase PF01026.21 ORY88821.1 - 1.8e-41 142.2 0.0 2.2e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RHH_4 PF13467.6 ORY88821.1 - 0.038 13.9 0.9 0.11 12.4 0.3 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix domain Response_reg PF00072.24 ORY88822.1 - 2.7e-48 162.8 0.1 7e-27 93.8 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORY88822.1 - 4.8e-43 146.2 0.1 1.8e-22 80.0 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY88822.1 - 5e-24 84.1 0.6 1.5e-11 44.1 0.1 3.1 2 1 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY88822.1 - 5.1e-06 26.7 0.0 1.9e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 PAS fold BolA PF01722.18 ORY88823.1 - 2.8e-16 59.5 0.0 3.3e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein CAF-1_p150 PF11600.8 ORY88823.1 - 0.037 13.7 0.3 0.048 13.4 0.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TatD_DNase PF01026.21 ORY88824.1 - 2.6e-44 151.5 0.1 3.1e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 ORY88824.1 - 0.012 15.4 0.0 0.076 12.8 0.0 2.4 1 1 0 1 1 1 0 Amidohydrolase Acid_PPase PF12689.7 ORY88825.1 - 1.2e-58 197.7 0.0 1.4e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase adh_short PF00106.25 ORY88826.1 - 3.9e-34 117.8 0.1 6.1e-34 117.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88826.1 - 8e-25 87.8 0.2 1.2e-24 87.1 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY88826.1 - 3.5e-11 43.3 1.1 9.4e-10 38.7 1.1 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY88826.1 - 1.9e-06 27.5 0.2 6.7e-06 25.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Flavi_DEAD PF07652.14 ORY88826.1 - 0.098 12.6 0.4 0.26 11.2 0.0 1.9 3 0 0 3 3 3 0 Flavivirus DEAD domain 3Beta_HSD PF01073.19 ORY88826.1 - 0.099 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ERAP1_C PF11838.8 ORY88827.1 - 7.7e-78 262.2 0.8 1.2e-77 261.5 0.8 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 ORY88827.1 - 1e-70 237.7 0.0 1.7e-70 237.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY88827.1 - 6e-36 124.4 0.0 6e-31 108.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Yae1_N PF09811.9 ORY88827.1 - 0.048 13.4 1.6 0.11 12.3 1.6 1.6 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Nuf2 PF03800.14 ORY88828.1 - 7.3e-27 94.2 0.1 1.6e-26 93.1 0.1 1.5 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 ORY88828.1 - 2.4e-19 69.5 16.8 2.4e-19 69.5 16.8 4.3 5 0 0 5 5 5 2 Designed helical repeat protein 10 domain Atg14 PF10186.9 ORY88828.1 - 0.052 12.6 32.5 0.3 10.1 11.6 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 ORY88828.1 - 0.054 13.0 38.7 0.1 12.1 12.6 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 ORY88828.1 - 5.3 7.3 49.1 1.8 8.8 17.0 3.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Complex1_LYR PF05347.15 ORY88829.1 - 7.6e-08 32.3 2.0 1.4e-07 31.5 2.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HGD-D PF06050.13 ORY88829.1 - 0.0038 17.0 0.0 0.0047 16.7 0.0 1.1 1 0 0 1 1 1 1 2-hydroxyglutaryl-CoA dehydratase, D-component PMSR PF01625.21 ORY88830.1 - 1.4e-63 213.6 2.4 1.8e-63 213.3 2.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Vsr PF03852.15 ORY88830.1 - 0.082 12.8 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 DNA mismatch endonuclease Vsr Ferritin_2 PF13668.6 ORY88831.1 - 2.4e-42 144.4 4.5 3.7e-42 143.7 4.5 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF1713 PF08213.11 ORY88832.1 - 1.4e-06 28.1 17.0 2.5e-06 27.3 17.0 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Inhibitor_I69 PF13734.6 ORY88832.1 - 0.65 10.5 0.1 0.65 10.5 0.1 2.4 2 1 0 2 2 2 0 Spi protease inhibitor Peptidase_M24 PF00557.24 ORY88833.1 - 1.1e-42 146.2 0.4 1.6e-42 145.5 0.4 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 ORY88833.1 - 0.0087 16.7 0.0 0.039 14.6 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain TatD_DNase PF01026.21 ORY88834.1 - 6.1e-41 140.5 0.0 7.5e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RHH_4 PF13467.6 ORY88834.1 - 0.09 12.7 0.4 0.22 11.4 0.4 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain SHR3_chaperone PF08229.11 ORY88835.1 - 4.3e-33 113.9 0.4 4.9e-33 113.7 0.4 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 EptA_B_N PF08019.12 ORY88835.1 - 0.4 10.6 5.7 0.14 12.0 2.9 1.6 2 0 0 2 2 2 0 Phosphoethanolamine transferase EptA/EptB BTB PF00651.31 ORY88836.1 - 0.00042 20.5 0.0 0.01 16.0 0.0 2.8 3 0 0 3 3 3 1 BTB/POZ domain Tetraspanin PF00335.20 ORY88838.1 - 0.0081 15.9 3.1 0.0081 15.9 3.1 1.8 1 1 1 2 2 2 1 Tetraspanin family Nup188 PF10487.9 ORY88839.1 - 2.3e-64 217.8 0.0 1.5e-63 215.1 0.0 2.2 2 1 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 ORY88839.1 - 4.5e-07 29.0 1.6 6.3e-07 28.5 0.7 1.7 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain Nup192 PF11894.8 ORY88839.1 - 2.2e-06 25.2 3.0 6.3e-05 20.3 0.0 3.4 4 0 0 4 4 4 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 Pkinase PF00069.25 ORY88840.1 - 9.4e-44 149.7 0.0 1.3e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88840.1 - 1.2e-17 64.0 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY88840.1 - 0.065 13.2 0.1 0.51 10.2 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY88840.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 ORY88840.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 ORY88841.1 - 1.6e-27 96.2 2.7 2.3e-27 95.7 2.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY88841.1 - 9.3e-23 81.0 2.4 1.3e-22 80.5 2.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY88841.1 - 4.6e-11 43.0 2.1 6.9e-10 39.1 2.0 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY88841.1 - 3.4e-07 30.0 0.4 4.9e-07 29.5 0.4 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY88841.1 - 0.0027 16.8 0.9 0.0039 16.2 0.9 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY88841.1 - 0.066 13.1 2.0 0.1 12.5 1.5 1.6 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY88841.1 - 0.14 11.5 1.5 0.27 10.6 1.3 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase MTABC_N PF16185.5 ORY88842.1 - 0.0024 17.4 2.9 0.0043 16.6 2.5 1.6 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region DUF2985 PF11204.8 ORY88842.1 - 0.06 13.5 2.1 1.4 9.1 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2985) FA_desaturase PF00487.24 ORY88843.1 - 2.2e-13 50.6 15.2 2.2e-13 50.6 15.2 1.7 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY88843.1 - 0.0063 16.6 0.0 0.016 15.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Urm1 PF09138.11 ORY88844.1 - 1.1e-28 99.4 0.0 1e-23 83.5 0.0 2.0 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) CAAD PF14159.6 ORY88844.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ThiS PF02597.20 ORY88844.1 - 0.059 14.0 0.0 0.079 13.6 0.0 1.2 1 0 0 1 1 1 0 ThiS family Maf1 PF09174.10 ORY88845.1 - 1.7e-34 119.5 0.0 1.3e-27 97.0 0.0 2.3 2 0 0 2 2 2 2 Maf1 regulator ATG16 PF08614.11 ORY88846.1 - 6.1e-05 23.3 31.1 0.0031 17.8 13.6 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 ORY88846.1 - 0.14 11.5 18.4 0.097 12.0 8.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YPEB PF14620.6 ORY88846.1 - 0.26 10.6 10.6 1.1 8.5 1.1 2.2 2 0 0 2 2 2 0 YpeB sporulation Exonuc_VII_L PF02601.15 ORY88846.1 - 1.1 8.8 11.7 3.3 7.2 1.4 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Cluap1 PF10234.9 ORY88846.1 - 1.5 8.1 14.3 1.4 8.2 3.6 2.7 3 0 0 3 3 3 0 Clusterin-associated protein-1 Golgin_A5 PF09787.9 ORY88846.1 - 2.1 7.8 22.0 0.26 10.7 7.6 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 LIM PF00412.22 ORY88847.1 - 5.4e-22 77.8 17.2 3.1e-11 43.3 3.8 3.2 3 0 0 3 3 3 3 LIM domain zf-RING_6 PF14835.6 ORY88847.1 - 5.1 7.0 7.2 2.8 7.9 2.8 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF3535 PF12054.8 ORY88848.1 - 7.3e-98 328.6 0.0 5.7e-95 319.1 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 ORY88848.1 - 6.3e-63 212.6 0.0 1e-62 211.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.22 ORY88848.1 - 3.4e-15 54.9 17.9 0.86 10.0 0.0 9.8 8 0 0 8 8 8 6 HEAT repeat Helicase_C PF00271.31 ORY88848.1 - 4.4e-15 56.0 0.0 1.1e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.7 ORY88848.1 - 0.00013 22.5 0.1 0.59 10.8 0.0 2.9 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORY88848.1 - 0.00027 21.4 22.8 3.3 8.3 0.1 10.1 9 1 2 11 11 11 2 HEAT-like repeat ResIII PF04851.15 ORY88848.1 - 0.00084 19.4 0.0 0.0021 18.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Arm PF00514.23 ORY88848.1 - 0.0067 16.4 0.1 0.48 10.6 0.0 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 ORY88848.1 - 0.017 15.0 0.1 0.72 9.7 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 ORY88848.1 - 1.2 9.6 23.5 5.5 7.5 1.0 7.7 7 3 0 7 7 7 0 HEAT repeats ABC_tran PF00005.27 ORY88849.1 - 1.5e-25 90.3 0.0 1.5e-24 87.1 0.0 2.3 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY88849.1 - 2.2e-09 37.6 0.1 0.00074 19.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY88849.1 - 0.002 17.6 0.0 0.023 14.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY88849.1 - 0.0049 16.6 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY88849.1 - 0.007 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_pol_3_Rpc31 PF11705.8 ORY88849.1 - 0.018 15.3 5.5 0.037 14.3 5.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Zeta_toxin PF06414.12 ORY88849.1 - 0.045 13.0 0.0 0.14 11.4 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 ORY88849.1 - 0.055 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY88849.1 - 0.075 13.4 0.0 0.37 11.2 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ORY88849.1 - 0.078 13.5 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY88849.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase WD40 PF00400.32 ORY88851.1 - 0.0027 18.5 2.1 0.67 10.9 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY88851.1 - 0.026 14.8 0.0 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Gar1 PF04410.14 ORY88852.1 - 6.4e-35 120.2 0.0 7.9e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region IF-2B PF01008.17 ORY88854.1 - 1.3e-09 37.6 0.0 5e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Initiation factor 2 subunit family DHHC PF01529.20 ORY88855.1 - 2.4e-12 47.1 0.1 2.4e-12 47.1 0.1 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase CDC50 PF03381.15 ORY88855.1 - 0.2 11.1 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family EcsB PF05975.12 ORY88855.1 - 3.4 6.4 7.8 1 8.1 1.4 2.0 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB DUF3237 PF11578.8 ORY88856.1 - 5.3e-30 104.2 0.0 6.2e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) AMP-binding PF00501.28 ORY88858.1 - 2.6e-96 322.8 0.2 3.6e-96 322.3 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY88858.1 - 0.00035 21.5 0.0 0.00099 20.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Csm1 PF12539.8 ORY88859.1 - 1.5e-12 48.0 0.4 4.9e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 PRC PF05239.16 ORY88859.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 PRC-barrel domain AsnA PF03590.15 ORY88859.1 - 1 9.1 6.6 0.14 11.9 0.3 2.1 2 0 0 2 2 2 0 Aspartate-ammonia ligase Chitin_synth_2 PF03142.15 ORY88860.1 - 3.3e-277 920.3 0.6 4.2e-277 919.9 0.6 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY88860.1 - 3.5e-11 43.4 0.0 2.6e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY88860.1 - 7e-10 39.1 6.3 5.3e-09 36.3 6.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY88860.1 - 0.00076 19.0 0.1 0.068 12.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY88860.1 - 0.038 13.8 0.0 0.68 9.7 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 TIMELESS PF04821.14 ORY88862.1 - 1.8e-73 247.2 1.5 1.8e-73 247.2 1.5 2.1 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 ORY88862.1 - 5.8e-12 45.6 1.4 5.8e-12 45.6 1.4 4.1 2 1 1 5 5 5 1 Timeless protein C terminal region RRS1 PF04939.12 ORY88863.1 - 1.4e-61 207.1 2.6 1.4e-61 207.1 2.6 1.9 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Spc7 PF08317.11 ORY88863.1 - 0.49 9.2 11.2 0.72 8.7 11.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Noggin PF05806.12 ORY88863.1 - 2.6 7.9 5.5 4.6 7.1 5.5 1.3 1 0 0 1 1 1 0 Noggin ARD PF03079.14 ORY88863.1 - 3.5 7.8 5.9 6.8 6.8 5.9 1.5 1 0 0 1 1 1 0 ARD/ARD' family DPM3 PF08285.11 ORY88864.1 - 2.2e-30 104.7 0.0 2.5e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Ufd2P_core PF10408.9 ORY88864.1 - 0.053 12.1 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core Crisp PF08562.10 ORY88865.1 - 2.1 9.0 5.7 0.38 11.4 1.4 1.9 2 0 0 2 2 2 0 Crisp Amidohydro_3 PF07969.11 ORY88866.1 - 2e-53 182.6 1.0 4.1e-53 181.5 1.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 ORY88866.1 - 0.00034 20.0 0.0 0.57 9.4 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family PWI PF01480.17 ORY88867.1 - 3.3e-09 36.9 0.9 5.5e-09 36.2 0.1 1.7 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 ORY88867.1 - 1.5e-06 27.9 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_methylase PF00145.17 ORY88867.1 - 0.042 13.2 0.7 0.072 12.4 0.7 1.4 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase TOM13 PF08219.11 ORY88868.1 - 8.7e-12 44.8 0.1 3.1e-11 43.1 0.1 2.0 1 0 0 1 1 1 1 Outer membrane protein TOM13 Apolipoprotein PF01442.18 ORY88868.1 - 5.7e-08 32.8 11.1 5.7e-08 32.8 11.1 1.9 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 ORY88868.1 - 0.0059 16.7 11.6 0.0059 16.7 11.6 3.2 2 2 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 ORY88868.1 - 0.0059 14.6 0.4 0.0084 14.1 0.4 1.1 1 0 0 1 1 1 1 Prominin Collagen_mid PF15984.5 ORY88868.1 - 0.0072 16.1 0.5 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Bacterial collagen, middle region ApoO PF09769.9 ORY88868.1 - 0.015 15.2 3.3 1.2 9.1 0.1 2.5 1 1 1 2 2 2 0 Apolipoprotein O DUF445 PF04286.12 ORY88868.1 - 0.038 13.8 2.5 0.064 13.0 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF1451 PF07295.11 ORY88868.1 - 0.039 14.0 5.2 0.093 12.8 5.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF883 PF05957.13 ORY88868.1 - 0.1 13.2 4.4 0.63 10.7 3.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) MT0933_antitox PF14013.6 ORY88868.1 - 0.36 11.2 11.9 2.1 8.7 1.2 3.9 2 2 1 3 3 3 0 MT0933-like antitoxin protein DUF1664 PF07889.12 ORY88868.1 - 4.8 7.2 11.2 0.32 11.0 4.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) REF PF05755.12 ORY88868.1 - 4.9 6.9 13.2 0.12 12.2 6.2 1.8 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) DUF3584 PF12128.8 ORY88868.1 - 5.3 4.4 14.5 0.0046 14.6 3.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Pam16 PF03656.13 ORY88869.1 - 3.7e-06 27.0 0.0 4.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 ORY88869.1 - 0.00059 19.9 0.0 0.00089 19.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Amidohydro_3 PF07969.11 ORY88870.1 - 2.9e-42 145.8 0.1 7.2e-27 95.0 0.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 ORY88870.1 - 0.046 13.0 0.0 2.3 7.4 0.0 2.7 2 1 0 3 3 3 0 Amidohydrolase family FAD_binding_2 PF00890.24 ORY88871.1 - 1.6e-125 419.5 3.7 2e-125 419.2 3.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ORY88871.1 - 1.8e-43 147.6 0.4 2.6e-43 147.0 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 ORY88871.1 - 1.5e-06 27.7 1.2 0.00073 18.9 0.4 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY88871.1 - 4.3e-06 26.1 1.4 0.024 13.7 2.2 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ORY88871.1 - 1.7e-05 24.2 0.5 0.011 15.0 0.1 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 ORY88871.1 - 0.00078 18.8 0.2 0.0017 17.7 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORY88871.1 - 0.084 11.9 0.2 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 ORY88871.1 - 0.097 12.2 2.7 0.37 10.3 2.7 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY88871.1 - 0.13 10.9 1.8 0.45 9.2 0.6 2.3 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 ORY88871.1 - 2.5 7.3 3.9 3.1 7.0 1.2 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cullin PF00888.22 ORY88874.1 - 2.3e-189 631.0 0.0 3.1e-189 630.6 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY88874.1 - 2.4e-27 94.8 2.3 2.4e-27 94.8 2.3 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 ORY88874.1 - 0.031 14.6 0.1 0.15 12.5 0.1 2.3 1 0 0 1 1 1 0 Penicillinase repressor EMP24_GP25L PF01105.24 ORY88874.1 - 0.067 13.1 0.3 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD NAD_binding_10 PF13460.6 ORY88875.1 - 6.9e-30 104.3 0.1 9.3e-30 103.9 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 ORY88875.1 - 0.048 13.8 0.2 0.49 10.5 0.1 2.4 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain RsfS PF02410.15 ORY88876.1 - 3.8e-10 40.1 0.0 8.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF1682 PF07946.14 ORY88876.1 - 0.093 11.9 3.0 0.11 11.7 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SET PF00856.28 ORY88877.1 - 9.7e-06 26.1 0.0 1.5e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY88878.1 - 1.2e-08 34.9 19.0 1.7e-08 34.4 19.0 1.3 1 0 0 1 1 1 1 MYND finger DUF668 PF05003.12 ORY88878.1 - 0.039 14.4 0.0 0.094 13.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF668) zf-HIT PF04438.16 ORY88878.1 - 0.24 11.3 14.2 0.45 10.4 14.2 1.5 1 0 0 1 1 1 0 HIT zinc finger DKCLD PF08068.12 ORY88880.1 - 3e-32 110.5 0.1 6.7e-31 106.1 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 ORY88880.1 - 1.9e-23 83.5 0.3 1.6e-20 74.0 0.3 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 ORY88880.1 - 1.5e-22 79.5 0.7 3.1e-22 78.5 0.7 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 ORY88880.1 - 4.8e-22 77.7 1.1 1e-21 76.7 1.1 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 ORY88880.1 - 0.001 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain Sigma_1s PF02454.16 ORY88880.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma 1s protein Ribosomal_L22e PF01776.17 ORY88881.1 - 6.6e-42 142.3 0.8 8.3e-42 142.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3646 PF12362.8 ORY88881.1 - 0.027 14.8 0.1 0.036 14.4 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Aldo_ket_red PF00248.21 ORY88882.1 - 3.4e-75 253.0 0.1 3.8e-75 252.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORY88883.1 - 3.3e-58 197.2 0.0 8.7e-58 195.8 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family OmpH PF03938.14 ORY88883.1 - 0.12 12.7 0.5 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ribosomal_L22e PF01776.17 ORY88884.1 - 4.7e-21 75.2 0.0 5.3e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family PRTase_3 PF15610.6 ORY88884.1 - 0.086 12.1 0.0 0.12 11.6 0.0 1.2 1 1 0 1 1 1 0 PRTase ComF-like PPP4R2 PF09184.11 ORY88885.1 - 1.6e-18 67.3 0.0 6.4e-18 65.3 0.0 2.0 1 1 0 1 1 1 1 PPP4R2 Dopey_N PF04118.14 ORY88886.1 - 5.9e-110 367.2 0.3 4.4e-109 364.3 0.0 2.5 3 0 0 3 3 3 1 Dopey, N-terminal EF-hand_7 PF13499.6 ORY88887.1 - 1.5e-10 41.4 1.3 7.6e-10 39.1 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY88887.1 - 5.4e-10 38.4 0.6 0.00019 21.1 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 ORY88887.1 - 8.9e-10 37.6 0.1 0.00047 19.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 ORY88887.1 - 2.6e-08 32.8 0.5 0.002 17.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORY88887.1 - 0.00029 20.6 0.4 0.4 10.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY88887.1 - 0.0039 17.5 0.3 0.74 10.1 0.3 2.6 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Asp_protease_2 PF13650.6 ORY88890.1 - 2.8e-08 34.3 0.2 3.1e-08 34.1 0.2 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 ORY88890.1 - 8.2e-08 32.7 0.1 9.1e-08 32.6 0.1 1.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 ORY88890.1 - 0.081 12.7 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease SPX PF03105.19 ORY88891.1 - 4.7 7.0 9.5 1.9 8.3 2.9 2.1 2 0 0 2 2 2 0 SPX domain Arginase PF00491.21 ORY88892.1 - 3.4e-83 279.4 0.4 4.4e-83 279.0 0.0 1.3 2 0 0 2 2 2 1 Arginase family UPF0489 PF12640.7 ORY88892.1 - 0.091 13.0 0.1 0.14 12.3 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain CDP-OH_P_transf PF01066.21 ORY88893.1 - 3.9e-12 46.7 0.1 1.1e-11 45.4 0.1 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MAP7 PF05672.11 ORY88893.1 - 0.22 11.2 0.3 0.3 10.8 0.3 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DASH_Dam1 PF08653.10 ORY88894.1 - 0.0045 16.8 0.1 4.3 7.2 0.0 2.5 2 0 0 2 2 2 2 DASH complex subunit Dam1 zf-AN1 PF01428.16 ORY88896.1 - 8.5e-12 45.0 4.2 8.5e-12 45.0 4.2 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.23 ORY88896.1 - 2.2e-11 43.3 0.0 6.1e-11 41.9 0.0 1.8 2 1 0 2 2 2 1 Ubiquitin family C5HCH PF17982.1 ORY88896.1 - 0.037 14.2 1.4 0.037 14.2 1.4 2.0 2 0 0 2 2 2 0 NSD Cys-His rich domain TBK1_ULD PF18396.1 ORY88896.1 - 0.075 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD PF11976.8 ORY88896.1 - 0.089 12.6 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like zf-MYND PF01753.18 ORY88897.1 - 1.1e-09 38.2 17.1 1.6e-09 37.6 17.1 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY88897.1 - 0.31 11.0 8.0 0.58 10.1 8.0 1.5 1 0 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.18 ORY88898.1 - 2.3e-10 40.4 12.1 3.6e-10 39.7 12.1 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY88898.1 - 0.019 14.9 9.9 0.041 13.8 9.9 1.6 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 ORY88898.1 - 7.5 6.9 10.0 17 5.8 10.0 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding COesterase PF00135.28 ORY88899.1 - 1.5e-31 109.9 0.1 1.7e-31 109.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF501 PF04417.12 ORY88900.1 - 6.5 6.6 5.2 2.1 8.1 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Ribosomal_L22e PF01776.17 ORY88901.1 - 4.3e-12 46.4 0.0 1.6e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Ribosomal L22e protein family Tubulin_3 PF14881.6 ORY88902.1 - 2.4e-17 63.2 0.0 3.7e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 ORY88902.1 - 2.2e-05 24.7 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain HMMR_N PF15905.5 ORY88903.1 - 0.011 15.2 0.2 0.016 14.7 0.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tombus_P19 PF03220.13 ORY88903.1 - 0.06 13.1 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Tombusvirus P19 core protein IFP_35_N PF07334.13 ORY88903.1 - 0.14 12.3 0.2 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus KH_8 PF17903.1 ORY88904.1 - 2.1e-31 107.8 0.0 3.8e-31 107.0 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ORY88904.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 KH domain Pkinase PF00069.25 ORY88905.1 - 9.9e-56 189.0 0.0 1.7e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88905.1 - 2.8e-38 131.7 0.0 5.4e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY88905.1 - 0.0002 20.3 0.0 0.0002 20.3 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase DUF1241 PF06840.11 ORY88905.1 - 0.0017 18.0 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) TFIIA PF03153.13 ORY88905.1 - 0.0039 17.2 23.2 0.0039 17.2 23.2 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Kinase-like PF14531.6 ORY88905.1 - 0.036 13.4 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like SOG2 PF10428.9 ORY88905.1 - 1.3 8.2 21.7 0.26 10.4 8.5 2.4 2 0 0 2 2 2 0 RAM signalling pathway protein Cyt-b5 PF00173.28 ORY88906.1 - 9.9e-22 76.9 0.1 1.1e-21 76.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DNA_primase_lrg PF04104.14 ORY88945.1 - 2.7e-86 289.3 0.0 3.7e-86 288.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit PNP_UDP_1 PF01048.20 ORY88946.1 - 9.7e-27 93.7 0.0 1.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Peptidase_C12 PF01088.21 ORY88947.1 - 1e-63 214.9 0.0 1.9e-63 214.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 ORY88947.1 - 5.6e-14 51.8 1.7 1.2e-13 50.7 1.7 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases GreA_GreB_N PF03449.15 ORY88947.1 - 0.094 12.9 0.5 0.094 12.9 0.5 2.0 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Seryl_tRNA_N PF02403.22 ORY88947.1 - 5.3 7.3 9.8 4.8 7.5 0.8 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SPRY PF00622.28 ORY88948.1 - 1.6e-22 79.8 0.1 2.5e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 SPRY domain Trypsin_2 PF13365.6 ORY88949.1 - 1.3e-13 52.1 0.9 1.2e-11 45.8 0.0 3.0 3 1 0 3 3 3 1 Trypsin-like peptidase domain Trypsin PF00089.26 ORY88949.1 - 0.00061 19.7 0.1 0.0036 17.1 0.0 2.0 1 1 1 2 2 2 1 Trypsin Peptidase_S29 PF02907.15 ORY88949.1 - 0.026 14.2 0.1 0.084 12.6 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease FMO-like PF00743.19 ORY88950.1 - 5.6e-16 58.1 0.0 9.9e-11 40.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY88950.1 - 5.5e-10 39.0 1.9 1.8e-09 37.3 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY88950.1 - 9.9e-08 31.6 0.7 1.2e-06 28.0 0.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY88950.1 - 1.9e-05 24.7 0.0 5.2e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY88950.1 - 0.00086 19.5 0.0 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY88950.1 - 0.054 14.1 0.8 5.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY88950.1 - 0.072 12.3 0.4 0.82 8.9 0.1 2.1 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 ORY88950.1 - 0.084 12.1 1.1 0.3 10.4 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORY88950.1 - 0.14 12.6 0.4 2.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 ORY88950.1 - 0.58 9.7 3.7 0.35 10.4 0.6 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Tim17 PF02466.19 ORY88951.1 - 3.8e-29 101.3 9.7 5.4e-29 100.8 9.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SAGA-Tad1 PF12767.7 ORY88952.1 - 5.9e-46 157.1 0.1 1.1e-45 156.2 0.0 1.5 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Pep1_7 PF17232.2 ORY88952.1 - 0.24 11.9 3.2 3.3 8.2 0.8 2.5 2 0 0 2 2 2 0 Elicitor peptide 1-7 DAO PF01266.24 ORY88953.1 - 2.8e-35 122.5 0.3 3.4e-35 122.3 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY88953.1 - 0.00013 22.0 0.1 0.22 11.5 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ORY88953.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 ORY88953.1 - 0.017 14.4 0.0 0.98 8.6 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY88953.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A K_oxygenase PF13434.6 ORY88953.1 - 0.19 10.8 0.0 0.72 8.9 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) UPF0052 PF01933.18 ORY88954.1 - 1.5e-50 172.1 0.0 2e-50 171.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 FAM72 PF14976.6 ORY88956.1 - 9.4e-20 71.2 5.9 1.6e-19 70.5 5.9 1.3 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 ORY88956.1 - 0.2 11.9 8.6 0.54 10.5 8.6 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DOCK_N PF16172.5 ORY88957.1 - 6.6e-110 367.6 0.0 9.8e-110 367.0 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 ORY88957.1 - 7.4e-82 275.7 0.1 3.3e-81 273.5 0.0 1.9 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 ORY88957.1 - 1e-50 172.3 0.0 7.5e-50 169.4 0.0 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF4487 PF14868.6 ORY88957.1 - 0.053 12.4 2.8 0.086 11.7 1.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4487) F-box-like PF12937.7 ORY88958.1 - 0.0004 20.2 0.3 0.0004 20.2 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY88958.1 - 1.6 8.7 9.7 11 6.0 0.4 3.7 3 0 0 3 3 3 0 F-box domain Oxysterol_BP PF01237.18 ORY88959.1 - 1.4e-116 389.4 0.0 3.6e-116 388.1 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 ORY88959.1 - 1e-17 64.2 0.1 1.9e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY88959.1 - 0.0056 17.2 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 ORY88959.1 - 0.14 12.3 0.3 5.3 7.2 0.3 2.3 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology Slx4 PF09494.10 ORY88960.1 - 7e-12 45.1 0.0 2.5e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Slx4 endonuclease Apt1 PF10351.9 ORY88961.1 - 9.9 4.9 16.7 0.34 9.7 3.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain TRAPP PF04051.16 ORY88962.1 - 1.1e-36 125.8 0.0 1.3e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component F-box-like PF12937.7 ORY88963.1 - 0.00014 21.7 0.4 0.00014 21.7 0.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY88963.1 - 2 8.4 11.1 4.4 7.3 0.8 3.5 3 0 0 3 3 3 0 F-box domain Pkinase PF00069.25 ORY88964.1 - 6.8e-53 179.7 0.0 1e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88964.1 - 2.1e-24 86.2 0.0 3.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ATG16 PF08614.11 ORY88964.1 - 0.00035 20.9 1.2 0.00035 20.9 1.2 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 ORY88964.1 - 0.019 15.4 8.0 0.047 14.1 4.8 2.6 2 0 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 ORY88964.1 - 0.063 13.9 1.9 1.3 9.6 3.1 2.5 2 1 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 ORY88964.1 - 0.084 13.0 4.0 0.24 11.5 4.0 1.8 1 0 0 1 1 1 0 bZIP transcription factor Csm1_N PF18504.1 ORY88964.1 - 0.13 12.6 0.6 0.38 11.1 0.6 1.8 1 0 0 1 1 1 0 Csm1 N-terminal domain SlyX PF04102.12 ORY88964.1 - 0.14 12.8 6.4 0.12 13.0 3.9 2.2 2 0 0 2 2 2 0 SlyX SHE3 PF17078.5 ORY88964.1 - 0.21 11.3 1.7 0.38 10.4 1.7 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 GrpE PF01025.19 ORY88964.1 - 0.38 10.4 3.4 0.24 11.0 1.4 1.6 2 0 0 2 2 2 0 GrpE TSC22 PF01166.18 ORY88964.1 - 3 8.2 10.5 0.51 10.7 1.3 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family CENP-H PF05837.12 ORY88964.1 - 3.7 8.0 7.0 2.3 8.7 4.7 1.8 2 0 0 2 2 2 0 Centromere protein H (CENP-H) M PF02370.16 ORY88964.1 - 4.9 8.1 4.9 2.1 9.2 1.8 2.1 2 0 0 2 2 2 0 M protein repeat Pkinase PF00069.25 ORY88965.1 - 7.3e-59 199.3 0.0 1.9e-58 197.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY88965.1 - 2.4e-28 99.2 0.0 4.7e-20 72.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY88965.1 - 8.8e-05 22.0 0.6 0.007 15.7 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 ORY88965.1 - 0.012 14.5 0.0 0.037 13.0 0.0 1.8 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY88965.1 - 0.013 14.9 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY88965.1 - 0.099 12.5 0.1 0.4 10.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Spindle_Spc25 PF08234.12 ORY88966.1 - 1.9e-20 72.8 0.2 4.2e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 ORY88966.1 - 0.0013 17.7 16.7 0.0018 17.2 16.7 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Orbi_VP5 PF00901.17 ORY88966.1 - 0.075 11.4 5.9 0.1 11.0 5.9 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Baculo_PEP_C PF04513.12 ORY88966.1 - 0.27 11.3 3.0 0.36 10.9 1.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Borrelia_P83 PF05262.11 ORY88966.1 - 0.29 9.6 11.3 0.35 9.3 11.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein I_LWEQ PF01608.17 ORY88966.1 - 0.56 10.4 12.4 0.89 9.8 12.4 1.3 1 0 0 1 1 1 0 I/LWEQ domain Seryl_tRNA_N PF02403.22 ORY88966.1 - 0.57 10.4 18.4 0.18 12.1 15.3 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 ORY88966.1 - 0.77 9.3 9.7 1 8.8 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 ORY88966.1 - 2.2 7.6 13.9 3.1 7.1 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 ORY88966.1 - 2.6 7.4 4.0 3.6 6.9 4.0 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 GBP_C PF02841.14 ORY88966.1 - 3.7 6.9 19.1 6.6 6.1 19.1 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain WDCP PF15390.6 ORY88966.1 - 4.8 5.4 8.0 6.2 5.1 8.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3128 PF11326.8 ORY88967.1 - 7.3e-26 90.4 2.1 1.1e-25 89.8 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) PLRV_ORF5 PF01690.17 ORY88967.1 - 0.48 9.1 3.4 0.7 8.5 3.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein BRCT_2 PF16589.5 ORY88968.1 - 1e-06 29.1 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY88968.1 - 2.1e-06 28.0 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY88968.1 - 0.00024 21.0 0.1 0.00038 20.3 0.1 1.4 1 0 0 1 1 1 1 twin BRCT domain SUR7 PF06687.12 ORY88969.1 - 9.8e-14 51.5 9.4 1.4e-13 51.0 9.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family mTERF PF02536.14 ORY88970.1 - 0.067 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 mTERF VHS PF00790.19 ORY88972.1 - 4e-24 85.1 0.0 1.4e-22 80.1 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 ORY88972.1 - 8.4e-17 61.1 7.8 1.4e-16 60.4 7.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 ORY88972.1 - 2.3e-06 27.1 8.8 0.00097 18.9 2.3 2.5 2 0 0 2 2 2 2 Ubiquitin interaction motif C1_1 PF00130.22 ORY88972.1 - 0.0093 15.8 4.6 0.035 14.0 2.3 2.1 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RNaseH_pPIWI_RE PF13032.6 ORY88972.1 - 0.0098 15.8 2.6 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 RNaseH domain of pPIWI_RE OAD_gamma PF04277.13 ORY88972.1 - 0.02 15.4 2.5 0.063 13.9 2.5 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DZR PF12773.7 ORY88972.1 - 0.045 13.8 8.3 0.14 12.2 5.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon LRR_4 PF12799.7 ORY88973.1 - 0.0038 17.6 22.2 0.95 10.0 0.0 6.2 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) PARM PF17061.5 ORY88973.1 - 0.0068 16.6 17.9 0.01 16.0 17.9 1.2 1 0 0 1 1 1 1 PARM LigT_PEase PF02834.16 ORY88973.1 - 0.1 12.8 0.0 0.42 10.8 0.0 2.0 1 0 0 1 1 1 0 LigT like Phosphoesterase LRR_6 PF13516.6 ORY88973.1 - 0.11 12.7 12.2 11 6.4 0.1 6.4 7 0 0 7 7 7 0 Leucine Rich repeat Dicty_REP PF05086.12 ORY88973.1 - 1.1 7.1 5.8 1.5 6.7 5.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SR-25 PF10500.9 ORY88973.1 - 1.2 8.8 12.1 0.15 11.6 7.2 2.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CDC27 PF09507.10 ORY88973.1 - 6.5 6.0 11.9 11 5.2 11.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Epimerase PF01370.21 ORY88974.1 - 4.2e-15 55.9 0.0 5.2e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY88974.1 - 2.2e-12 47.0 0.0 3.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY88974.1 - 1e-07 31.4 0.1 3.9e-06 26.2 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 ORY88974.1 - 2.2e-07 30.3 0.0 3.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY88974.1 - 6.8e-07 28.6 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.23 ORY88974.1 - 0.015 15.4 0.1 0.035 14.2 0.1 1.7 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ORY88974.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF2456 PF10445.9 ORY88975.1 - 5.7e-18 64.8 6.3 1e-17 64.0 6.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) zf-primase PF09329.11 ORY88976.1 - 0.54 10.1 3.2 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 Primase zinc finger FHA PF00498.26 ORY88977.1 - 3.9e-08 33.5 0.0 8.1e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 FHA domain HpcH_HpaI PF03328.14 ORY88978.1 - 1.4e-30 106.1 0.0 1.6e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 ORY88978.1 - 0.0041 16.1 0.4 0.006 15.5 0.4 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Response_reg PF00072.24 ORY88979.1 - 4.2e-24 84.9 0.2 9.7e-24 83.7 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY88979.1 - 3.1e-14 52.7 0.7 1.3e-13 50.8 0.2 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 ORY88979.1 - 4.2e-14 53.0 0.3 4.9e-12 46.3 0.8 2.8 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 ORY88979.1 - 7.3e-12 45.4 0.2 7.6e-11 42.2 0.2 2.5 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ORY88979.1 - 4.4e-08 33.4 0.2 0.031 14.5 0.0 3.8 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 ORY88979.1 - 7e-08 32.7 0.0 0.0014 18.9 0.0 3.8 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 ORY88979.1 - 1.5e-06 28.2 0.1 0.012 15.6 0.0 4.3 5 0 0 5 5 5 2 PAS fold PAS_10 PF13596.6 ORY88979.1 - 0.15 12.6 0.0 3.9 8.1 0.0 2.8 3 0 0 3 3 3 0 PAS domain Nuc_N PF14448.6 ORY88980.1 - 0.0015 18.3 0.6 0.0041 17.0 0.6 1.7 1 0 0 1 1 1 1 Nuclease N terminal REV PF00424.18 ORY88980.1 - 0.52 10.4 6.6 1.8 8.7 6.6 1.8 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Zn_clus PF00172.18 ORY88981.1 - 2.4e-05 24.3 5.7 4.2e-05 23.6 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T3SS_needle_E PF08988.10 ORY88981.1 - 0.076 13.2 0.6 2.2 8.5 0.1 2.5 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle 2-Hacid_dh_C PF02826.19 ORY88982.1 - 6.2e-45 152.7 0.0 9e-45 152.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY88982.1 - 6.9e-19 67.8 0.0 8.4e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY88982.1 - 5.9e-07 29.8 0.0 9.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase WD40 PF00400.32 ORY88983.1 - 2.7e-44 148.2 36.5 7.1e-08 33.0 0.2 12.2 12 1 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 ORY88983.1 - 4.1e-20 72.1 1.9 7.4e-20 71.3 1.9 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ORY88983.1 - 6.6e-19 68.0 3.8 0.0031 17.8 0.1 9.3 3 2 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY88983.1 - 3.5e-05 22.9 1.6 8.9 5.2 0.0 5.4 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 ORY88983.1 - 0.0055 16.0 0.0 0.26 10.5 0.0 2.4 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 ORY88983.1 - 0.0064 15.2 0.0 4.5 5.8 0.0 3.5 4 0 0 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY88983.1 - 0.0075 15.6 0.0 20 4.4 0.0 4.0 4 0 0 4 4 4 0 WD40-like domain AP3D1 PF06375.11 ORY88983.1 - 0.012 15.9 0.5 0.026 14.7 0.5 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 eIF2A PF08662.11 ORY88983.1 - 0.039 13.8 0.0 1.3 8.8 0.0 3.2 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 ORY88983.1 - 1.2 8.0 4.3 18 4.1 0.0 3.7 4 0 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain LCM PF04072.14 ORY88984.1 - 8e-21 74.8 0.0 1.5e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF3446 PF11928.8 ORY88985.1 - 0.0079 16.5 5.1 0.0079 16.5 5.1 2.0 2 0 0 2 2 2 1 Early growth response N-terminal domain TPR_14 PF13428.6 ORY88985.1 - 0.016 15.9 1.4 15 6.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_I_TF PF04090.12 ORY88985.1 - 0.021 14.3 0.3 0.089 12.3 0.2 1.9 1 1 1 2 2 2 0 RNA polymerase I specific initiation factor AF-4 PF05110.13 ORY88985.1 - 0.022 12.9 10.7 0.032 12.4 10.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4611 PF15387.6 ORY88985.1 - 0.077 13.2 2.3 0.22 11.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) IMUP PF15761.5 ORY88985.1 - 0.51 11.0 11.0 1.1 10.0 11.0 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Herpes_pp85 PF04637.12 ORY88985.1 - 2.9 6.2 5.0 4.6 5.5 5.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-CCCH_4 PF18044.1 ORY88986.1 - 0.0088 15.8 0.8 0.0088 15.8 0.8 3.4 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY88986.1 - 7.2 6.8 15.7 0.38 10.9 1.1 3.9 2 2 0 3 3 3 0 Zinc finger domain AA_permease PF00324.21 ORY88987.1 - 1.7e-102 343.5 46.0 2.1e-102 343.2 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY88987.1 - 1.6e-30 106.3 49.5 1.9e-30 106.0 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease Asn_synthase PF00733.21 ORY88988.1 - 1.1e-17 64.8 0.0 1.6e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORY88988.1 - 0.00011 22.2 0.0 0.00039 20.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY88988.1 - 0.014 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutamine amidotransferase domain Cmc1 PF08583.10 ORY88989.1 - 1.7e-17 63.2 3.0 1.9e-17 63.0 3.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3128 PF11326.8 ORY88989.1 - 0.57 10.6 7.6 5.8 7.3 7.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) EHN PF06441.12 ORY88991.1 - 2.1e-34 118.2 0.1 3.4e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 ORY88991.1 - 2.5e-09 37.2 0.0 3.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MIP PF00230.20 ORY88992.1 - 3.5e-37 128.3 17.1 4.6e-37 127.9 17.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRA1 PF03208.19 ORY88992.1 - 0.71 9.5 3.3 2.3 7.8 2.4 2.1 1 1 1 2 2 2 0 PRA1 family protein Oxidored_FMN PF00724.20 ORY88993.1 - 1.1e-87 294.6 0.0 1.2e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Alpha-amylase_N PF02903.14 ORY88993.1 - 0.089 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain Oxidored_FMN PF00724.20 ORY88994.1 - 6.3e-86 288.7 0.0 7.3e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3915 PF13054.6 ORY88995.1 - 0.15 12.1 0.4 0.25 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Cript PF10235.9 ORY88996.1 - 6.4e-23 81.1 11.9 6.4e-23 81.1 11.9 2.2 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 ORY88996.1 - 0.0022 18.3 9.0 0.0022 18.3 9.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Rhodanese_C PF12368.8 ORY88996.1 - 0.0082 16.5 1.7 0.0082 16.5 1.7 2.0 2 0 0 2 2 2 1 Rhodanase C-terminal DUF1272 PF06906.11 ORY88996.1 - 0.34 11.0 11.4 0.87 9.7 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zinc_ribbon_2 PF13240.6 ORY88996.1 - 1.3 8.8 8.9 8.8 6.2 3.3 3.2 3 0 0 3 3 3 0 zinc-ribbon domain C1_1 PF00130.22 ORY88996.1 - 1.5 8.7 14.4 6.5 6.7 0.4 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 ORY88996.1 - 5 7.2 14.4 2.4 8.2 3.7 2.9 2 1 1 3 3 3 0 Double zinc ribbon PLATZ PF04640.14 ORY88996.1 - 8.7 7.0 10.0 1.9 9.2 0.8 2.9 2 1 1 3 3 3 0 PLATZ transcription factor DEAD PF00270.29 ORY88997.1 - 2e-47 161.2 0.0 6e-46 156.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY88997.1 - 1.2e-30 106.0 0.0 6.3e-29 100.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Zip PF02535.22 ORY88997.1 - 0.044 13.0 1.1 0.062 12.5 1.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CTNNB1_binding PF08347.11 ORY88997.1 - 0.045 13.9 4.5 0.074 13.2 4.5 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding ERCC3_RAD25_C PF16203.5 ORY88997.1 - 0.065 12.4 0.0 0.065 12.4 0.0 2.2 2 0 0 2 2 1 0 ERCC3/RAD25/XPB C-terminal helicase DDHD PF02862.17 ORY88997.1 - 0.15 12.2 5.7 0.24 11.5 5.7 1.3 1 0 0 1 1 1 0 DDHD domain CMS1 PF14617.6 ORY88997.1 - 0.33 10.3 0.0 0.33 10.3 0.0 3.4 2 1 0 2 2 1 0 U3-containing 90S pre-ribosomal complex subunit Presenilin PF01080.17 ORY88997.1 - 0.39 9.4 11.8 0.53 9.0 11.8 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 ORY88997.1 - 0.57 9.8 24.0 0.95 9.0 24.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2052 PF09747.9 ORY88997.1 - 0.71 10.0 16.0 1.2 9.3 16.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SOBP PF15279.6 ORY88997.1 - 0.97 10.0 11.1 1.5 9.3 11.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CPSF100_C PF13299.6 ORY88997.1 - 1.1 9.5 15.2 1.4 9.1 13.8 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4778 PF16008.5 ORY88997.1 - 2.4 8.2 9.7 3.7 7.5 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Roughex PF06020.11 ORY88997.1 - 2.7 7.0 14.3 4 6.4 14.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Tim54 PF11711.8 ORY88997.1 - 3.3 6.4 12.9 5.4 5.7 12.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_polI_A34 PF08208.11 ORY88997.1 - 4.6 7.3 34.2 11 6.0 34.2 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MCM_bind PF09739.9 ORY88997.1 - 5.8 5.2 13.8 8.9 4.6 13.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF2151 PF10221.9 ORY88997.1 - 6.7 5.2 12.5 9.6 4.7 12.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Rrn6 PF10214.9 ORY88997.1 - 6.7 5.1 13.3 11 4.4 13.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor GAGA_bind PF06217.12 ORY88997.1 - 8.4 6.6 13.6 15 5.7 13.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Glyco_hydro_15 PF00723.21 ORY88998.1 - 9.9e-60 202.6 0.0 1.2e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Oxysterol_BP PF01237.18 ORY88999.1 - 5.8e-86 288.7 0.0 5.8e-84 282.1 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein RNA_pol_Rpb5_C PF01191.19 ORY89001.1 - 6.8e-33 112.4 0.3 1.2e-32 111.5 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 ORY89001.1 - 2.7e-25 88.7 0.1 4.9e-25 87.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 ORY89001.1 - 0.033 14.2 0.1 0.063 13.3 0.1 1.5 1 1 0 1 1 1 0 Restriction endonuclease Mrr_cat_2 PF13156.6 ORY89001.1 - 0.054 13.4 0.1 0.089 12.7 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease Hexapep PF00132.24 ORY89002.1 - 3.1e-13 48.9 5.7 5.3e-10 38.6 2.5 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 ORY89002.1 - 3.9e-12 46.2 0.1 7.5e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 ORY89002.1 - 9.9e-12 44.4 8.0 2.1e-10 40.2 1.7 3.4 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Phos_pyr_kin PF08543.12 ORY89003.1 - 1.3e-09 37.8 0.0 3.7e-09 36.3 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ORY89003.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TFIIS_C PF01096.18 ORY89004.1 - 4.1e-15 55.4 2.7 4.1e-15 55.4 2.7 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORY89004.1 - 3.7e-06 26.7 7.1 4.3e-05 23.3 0.1 3.1 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 ORY89004.1 - 5.8e-05 23.0 5.6 0.041 13.9 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon Zn-ribbon_8 PF09723.10 ORY89004.1 - 0.002 18.2 8.5 0.58 10.3 0.6 3.3 3 0 0 3 3 3 1 Zinc ribbon domain tRNA-synt_1f PF01921.18 ORY89004.1 - 0.01 14.8 0.7 0.015 14.3 0.7 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) HypA PF01155.19 ORY89004.1 - 0.012 15.6 6.3 0.39 10.8 1.7 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Nudix_N_2 PF14803.6 ORY89004.1 - 0.033 14.1 10.6 0.74 9.8 3.1 3.6 3 1 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 ORY89004.1 - 0.037 13.7 10.8 11 5.9 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain GTA_TIM PF13547.6 ORY89004.1 - 0.043 13.1 0.1 0.049 12.9 0.1 1.0 1 0 0 1 1 1 0 GTA TIM-barrel-like domain Zn_Tnp_IS1595 PF12760.7 ORY89004.1 - 0.066 13.2 2.8 0.41 10.7 0.6 2.7 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn_Tnp_IS91 PF14319.6 ORY89004.1 - 0.073 13.1 5.5 7.7 6.6 0.2 3.0 1 1 1 3 3 3 0 Transposase zinc-binding domain zf_UBZ PF18439.1 ORY89004.1 - 0.11 12.1 10.4 3.7 7.2 0.3 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 ORY89004.1 - 0.14 11.9 12.9 7.7 6.4 0.1 4.1 4 0 0 4 4 4 0 A2L zinc ribbon domain DUF3268 PF11672.8 ORY89004.1 - 0.17 12.2 0.6 0.17 12.2 0.6 2.4 2 1 0 2 2 2 0 zinc-finger-containing domain HalOD2 PF18547.1 ORY89004.1 - 0.24 11.3 7.5 5 7.1 0.1 3.9 3 1 0 3 3 3 0 Halobacterial output domain 2 Baculo_LEF5_C PF11792.8 ORY89004.1 - 0.31 10.8 9.1 0.072 12.8 3.3 2.7 2 1 1 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain TF_Zn_Ribbon PF08271.12 ORY89004.1 - 0.39 10.3 16.6 0.25 10.9 3.7 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 ORY89004.1 - 0.83 10.1 8.6 4.9 7.6 0.4 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-C4_Topoisom PF01396.19 ORY89004.1 - 0.98 9.3 10.5 0.17 11.7 2.1 3.5 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-CSL PF05207.13 ORY89004.1 - 1.1 9.1 10.4 1.4 8.7 2.4 2.7 2 2 0 2 2 2 0 CSL zinc finger OrfB_Zn_ribbon PF07282.11 ORY89004.1 - 1.7 8.6 9.1 1.7 8.6 0.1 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Prok-RING_1 PF14446.6 ORY89004.1 - 1.8 8.5 9.6 0.18 11.7 1.2 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zinc_ribbon_13 PF09855.9 ORY89004.1 - 2.2 8.5 11.5 24 5.2 5.2 3.9 3 1 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) eIF-5_eIF-2B PF01873.17 ORY89004.1 - 2.3 8.1 7.1 0.26 11.2 0.6 2.4 2 1 1 3 3 3 0 Domain found in IF2B/IF5 Rubredoxin_2 PF18073.1 ORY89004.1 - 2.4 8.0 14.2 0.98 9.2 0.6 4.0 4 0 0 4 4 4 0 Rubredoxin metal binding domain RecR PF02132.15 ORY89004.1 - 3 7.5 9.5 8.8 6.0 0.3 3.3 3 0 0 3 3 3 0 RecR protein zf-ribbon_3 PF13248.6 ORY89004.1 - 3.6 7.1 14.6 34 4.0 0.1 4.0 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ORY89004.1 - 5.4 7.8 11.5 3.5 8.4 3.0 3.1 1 1 1 3 3 3 0 zinc-ribbon family NOB1_Zn_bind PF08772.11 ORY89004.1 - 7.4 6.8 11.2 33 4.7 0.1 3.7 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like SET PF00856.28 ORY89005.1 - 9.1e-13 48.9 0.0 7.5e-12 46.0 0.0 2.6 2 1 0 2 2 2 1 SET domain Cep57_MT_bd PF06657.13 ORY89005.1 - 0.077 13.5 0.3 0.27 11.7 0.3 1.9 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DMPK_coil PF08826.10 ORY89005.1 - 0.21 11.7 2.1 0.61 10.2 2.1 1.9 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF2884 PF11101.8 ORY89005.1 - 2.4 7.6 4.3 7.6 6.0 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) SET PF00856.28 ORY89006.1 - 4.1e-13 50.1 0.0 3.9e-12 46.9 0.0 2.3 1 1 0 1 1 1 1 SET domain Y_phosphatase PF00102.27 ORY89007.1 - 1.1e-55 188.8 0.1 1.3e-49 168.9 0.0 2.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 ORY89007.1 - 0.00034 21.1 0.0 0.0007 20.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 ORY89007.1 - 0.00086 19.3 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF3498 PF12004.8 ORY89007.1 - 0.76 8.9 7.7 2.1 7.4 7.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) BRCT PF00533.26 ORY89008.1 - 0.00036 20.9 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain TIMELESS_C PF05029.13 ORY89008.1 - 0.21 10.7 4.6 0.055 12.6 1.0 1.8 2 0 0 2 2 2 0 Timeless protein C terminal region DUF2474 PF10617.9 ORY89009.1 - 0.056 13.3 1.5 0.099 12.5 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) MFS_1 PF07690.16 ORY89010.1 - 5.5e-41 140.7 19.5 6.8e-41 140.4 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89010.1 - 3e-14 52.8 10.4 4.8e-14 52.1 10.4 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 ORY89010.1 - 2e-06 26.6 1.7 2.6e-06 26.2 1.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 ORY89010.1 - 3.5e-05 23.3 3.6 5.8e-05 22.5 3.6 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB FPN1 PF06963.12 ORY89010.1 - 0.016 13.8 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) S10_plectin PF03501.15 ORY89010.1 - 0.1 12.7 0.3 0.21 11.7 0.3 1.5 1 0 0 1 1 1 0 Plectin/S10 domain adh_short PF00106.25 ORY89012.1 - 2.7e-43 147.7 0.0 3.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY89012.1 - 2.5e-34 118.9 0.0 2.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY89012.1 - 2.5e-08 34.1 0.0 4.9e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 ORY89012.1 - 3.2e-05 23.5 0.0 4.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY89012.1 - 9.3e-05 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY89012.1 - 0.043 13.7 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY89012.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase LytR_C PF13399.6 ORY89012.1 - 0.14 13.2 0.0 0.32 12.0 0.0 1.6 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator F-box-like PF12937.7 ORY89013.1 - 0.0055 16.6 2.7 0.0067 16.3 0.1 2.6 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 ORY89013.1 - 0.19 11.6 3.3 2 8.3 0.2 3.0 3 0 0 3 3 3 0 F-box LRR_4 PF12799.7 ORY89013.1 - 0.74 10.3 8.9 14 6.2 1.5 5.2 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) DLH PF01738.18 ORY89014.1 - 1.2e-18 67.5 0.0 3.5e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY89014.1 - 0.058 13.0 0.1 0.19 11.3 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Adeno_E3_CR2 PF02439.15 ORY89016.1 - 0.19 11.5 3.0 0.33 10.8 3.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FAD_binding_3 PF01494.19 ORY89018.1 - 1e-23 84.2 0.2 6.7e-23 81.5 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY89018.1 - 4.9e-09 35.8 1.1 0.00028 20.2 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY89018.1 - 1.1e-06 28.4 4.4 0.0044 16.6 0.6 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY89018.1 - 6.9e-06 25.4 0.9 1.3e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY89018.1 - 7e-05 23.0 0.6 0.00015 21.9 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY89018.1 - 7.1e-05 21.7 0.2 0.0019 17.0 0.6 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORY89018.1 - 0.00025 21.5 0.1 0.33 11.5 0.6 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY89018.1 - 0.0023 17.1 1.6 0.0054 15.9 1.5 1.8 2 1 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 ORY89018.1 - 0.011 15.0 0.3 13 4.9 0.1 3.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ORY89018.1 - 0.024 14.0 2.2 0.11 11.8 0.8 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ORY89018.1 - 0.024 14.5 0.3 0.045 13.6 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 ORY89018.1 - 0.081 11.8 0.3 6.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.17 ORY89018.1 - 0.17 11.1 0.2 0.33 10.2 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_4 PF01565.23 ORY89019.1 - 2.7e-26 92.0 0.0 8.9e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 ORY89019.1 - 6.9e-11 42.2 0.0 2.2e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain MFS_1 PF07690.16 ORY89020.1 - 6.1e-20 71.4 39.0 3e-17 62.6 31.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Fcf1 PF04900.12 ORY89021.1 - 3.5e-29 101.1 0.0 5.7e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Fcf1 SRP-alpha_N PF04086.13 ORY89021.1 - 7.5 6.4 15.6 11 5.9 15.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal bZIP_1 PF00170.21 ORY89022.1 - 7.8e-11 41.9 3.4 7.8e-11 41.9 3.4 1.7 2 0 0 2 2 2 1 bZIP transcription factor DUF1043 PF06295.12 ORY89022.1 - 0.95 9.5 5.8 0.12 12.4 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) TMPIT PF07851.13 ORY89022.1 - 4.5 6.4 4.9 0.48 9.6 0.8 1.4 2 0 0 2 2 2 0 TMPIT-like protein Metallophos PF00149.28 ORY89023.1 - 1.8e-12 48.2 0.9 5.3e-12 46.7 0.9 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY89023.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-RING_2 PF13639.6 ORY89025.1 - 6.9e-12 45.5 8.4 1.1e-11 44.9 8.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY89025.1 - 1.2e-07 31.4 4.3 1.9e-07 30.7 4.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY89025.1 - 2.8e-06 27.0 6.6 4.5e-06 26.4 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY89025.1 - 2.8e-05 24.3 5.8 6.8e-05 23.1 5.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY89025.1 - 5.2e-05 23.0 4.9 8.4e-05 22.4 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY89025.1 - 0.00031 20.7 2.1 0.00061 19.8 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORY89025.1 - 0.002 17.9 6.0 0.0035 17.1 6.0 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 ORY89025.1 - 0.014 15.4 3.8 0.022 14.7 3.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 ORY89025.1 - 0.019 15.2 2.6 0.036 14.2 2.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORY89025.1 - 0.019 14.8 5.6 0.16 11.9 6.1 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 ORY89025.1 - 0.12 12.5 5.2 0.21 11.7 5.2 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 ORY89025.1 - 0.15 11.9 3.3 0.24 11.3 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY89025.1 - 0.31 11.1 7.8 0.64 10.1 7.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 ORY89025.1 - 2.6 8.0 4.5 4.5 7.3 4.5 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 ORY89025.1 - 6 6.9 7.9 3.6 7.6 5.4 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Aldolase_II PF00596.21 ORY89026.1 - 4.8e-47 160.3 0.5 5.7e-47 160.1 0.5 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain S6OS1 PF15676.5 ORY89027.1 - 0.003 16.1 0.2 0.0038 15.8 0.2 1.1 1 0 0 1 1 1 1 Six6 opposite strand transcript 1 family TEX13 PF15186.6 ORY89027.1 - 0.79 9.4 6.3 1.2 8.8 6.3 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family PUF PF00806.19 ORY89028.1 - 2.4e-60 196.9 6.7 7.5e-09 34.8 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 ORY89028.1 - 0.00038 20.8 1.1 5.3 7.4 0.0 4.3 1 1 2 4 4 4 2 CPL (NUC119) domain DUF3447 PF11929.8 ORY89028.1 - 0.0018 18.2 0.9 3.9 7.5 0.3 3.2 2 1 0 3 3 3 2 Domain of unknown function (DUF3447) Aminotran_5 PF00266.19 ORY89029.1 - 1.5e-05 24.1 0.0 2.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY89029.1 - 0.00093 18.6 0.1 0.0015 17.9 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family TRAPP PF04051.16 ORY89030.1 - 8.5e-38 129.3 0.0 1.1e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Actin PF00022.19 ORY89031.1 - 5.8e-59 199.7 0.0 2.4e-34 118.6 0.0 2.2 2 0 0 2 2 2 2 Actin Noggin PF05806.12 ORY89031.1 - 0.088 12.7 3.9 0.2 11.5 3.9 1.6 1 0 0 1 1 1 0 Noggin RseA_C PF03873.13 ORY89031.1 - 0.44 10.8 2.5 5 7.4 1.0 3.0 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Fungal_trans PF04082.18 ORY89032.1 - 3.9e-16 58.9 0.1 8e-16 57.9 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain KH_1 PF00013.29 ORY89034.1 - 2e-12 46.8 0.0 1.1e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 KH domain Skp1_POZ PF03931.15 ORY89034.1 - 0.22 11.7 0.1 9.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain DUF218 PF02698.17 ORY89035.1 - 0.01 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain Ribosomal_S26e PF01283.19 ORY89036.1 - 2.4e-52 175.9 4.7 2.9e-52 175.6 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.7 ORY89036.1 - 0.028 15.0 0.7 0.065 13.8 0.7 1.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain Avl9 PF09794.9 ORY89037.1 - 1.8e-133 444.9 0.0 2.2e-133 444.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 ORY89037.1 - 1.2e-11 44.6 0.0 1.5e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 ORY89037.1 - 3.8e-11 43.1 0.0 3.9e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 ORY89037.1 - 2e-08 34.8 0.0 4.9e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking GntR PF00392.21 ORY89037.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PAC2 PF09754.9 ORY89038.1 - 9.6e-15 55.2 0.1 1.2e-14 54.8 0.1 1.1 1 0 0 1 1 1 1 PAC2 family BDHCT_assoc PF16204.5 ORY89038.1 - 0.068 12.9 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein eRF1_3 PF03465.15 ORY89040.1 - 0.0001 22.8 0.1 0.00013 22.4 0.1 1.2 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 ORY89041.1 - 2.8e-47 160.4 0.1 4.5e-47 159.7 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORY89041.1 - 2.2e-35 121.5 0.0 4.3e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 ORY89041.1 - 1.2e-19 70.6 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 ORY89041.1 - 1.7e-10 41.3 0.3 3.7e-10 40.2 0.1 1.6 2 0 0 2 2 2 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 ORY89041.1 - 2.6e-08 34.2 0.1 5.2e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 DUF2415 PF10313.9 ORY89042.1 - 3e-13 49.4 1.5 3.7e-12 46.0 0.2 3.2 4 0 0 4 4 4 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 ORY89042.1 - 0.00081 19.6 0.1 11 6.3 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY89042.1 - 0.041 14.8 1.2 19 6.3 0.1 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Pox_Ag35 PF03286.14 ORY89042.1 - 1.4 8.7 5.4 4.3 7.1 0.3 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PGA2 PF07543.12 ORY89042.1 - 1.7 8.6 5.3 3.4 7.7 0.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 WD40 PF00400.32 ORY89043.1 - 5.2e-28 96.7 12.6 7.6e-08 32.9 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89043.1 - 5.9e-09 36.1 0.1 0.21 11.9 0.0 5.7 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 ORY89043.1 - 7.8e-07 28.7 0.6 0.091 12.7 0.0 4.0 4 0 0 4 4 4 2 PQQ enzyme repeat WD40_like PF17005.5 ORY89043.1 - 1.6e-06 27.7 0.0 3.1e-05 23.5 0.0 2.2 1 1 0 2 2 2 1 WD40-like domain PQQ_2 PF13360.6 ORY89043.1 - 7.6e-05 22.4 1.5 0.012 15.2 0.8 3.0 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.6 ORY89043.1 - 0.0018 18.7 2.6 5.2 7.7 0.0 4.2 4 0 0 4 4 4 1 PQQ-like domain BBS2_Mid PF14783.6 ORY89043.1 - 0.0066 16.5 0.0 5.4 7.1 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region F-box-like PF12937.7 ORY89044.1 - 1.1e-18 66.8 1.9 2.5e-08 33.7 0.0 3.8 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 ORY89044.1 - 0.00074 19.3 1.4 1 9.3 0.0 4.0 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 ORY89044.1 - 0.086 12.7 0.1 0.37 10.7 0.1 2.2 1 1 0 1 1 1 0 F-box LRR_4 PF12799.7 ORY89044.1 - 0.14 12.6 15.0 2.4 8.7 0.4 7.4 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY89044.1 - 1.8 8.8 4.8 23 5.4 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat CMAS PF02353.20 ORY89045.1 - 1.2e-31 110.1 0.3 1.8e-31 109.4 0.0 1.4 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY89045.1 - 9.1e-12 45.5 0.0 1.8e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY89045.1 - 3e-10 40.1 0.0 5.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY89045.1 - 3.9e-10 40.2 0.0 7.5e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY89045.1 - 1.4e-09 38.6 0.0 3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY89045.1 - 4.4e-09 36.4 0.0 8.4e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY89045.1 - 9.7e-07 28.5 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ORY89045.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 ORY89045.1 - 0.0071 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase tRNA_U5-meth_tr PF05958.11 ORY89045.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase YfkB PF08756.10 ORY89045.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 YfkB-like domain PCMT PF01135.19 ORY89045.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1771 PF08590.10 ORY89046.1 - 1.2e-20 73.6 3.1 2e-20 72.9 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 ORY89046.1 - 7.7e-12 45.4 0.1 1.8e-11 44.3 0.1 1.6 1 0 0 1 1 1 1 Smr domain LRRNT PF01462.18 ORY89046.1 - 0.059 13.0 1.2 0.12 12.0 1.2 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain KTI12 PF08433.10 ORY89047.1 - 3.9e-80 269.2 0.0 4.4e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 ORY89047.1 - 3.9e-12 46.5 0.0 1.3e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY89047.1 - 0.042 14.4 0.0 0.081 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 ORY89047.1 - 0.049 12.9 0.0 0.085 12.1 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 ORY89047.1 - 0.098 12.9 0.1 1.6 8.9 0.1 2.7 1 1 0 1 1 1 0 AAA domain ECH_1 PF00378.20 ORY89048.1 - 2.3e-87 292.4 0.4 2.9e-87 292.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY89048.1 - 4e-38 131.8 0.9 1.1e-34 120.4 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORY89048.1 - 4.2e-05 23.6 0.3 0.0077 16.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 DUF5034 PF16437.5 ORY89048.1 - 0.092 12.7 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5034) WW PF00397.26 ORY89049.1 - 0.0043 17.1 3.2 0.0043 17.1 3.2 2.2 2 0 0 2 2 2 1 WW domain WW PF00397.26 ORY89050.1 - 0.00099 19.1 0.3 0.0019 18.2 0.3 1.5 1 0 0 1 1 1 1 WW domain Nucleo_P87 PF07267.11 ORY89050.1 - 0.0059 15.5 2.3 0.0075 15.2 2.3 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 ORY89050.1 - 0.022 13.1 3.2 0.026 12.8 3.2 1.2 1 0 0 1 1 1 0 CDC45-like protein PAM2 PF07145.15 ORY89052.1 - 0.00024 20.6 3.5 0.061 13.0 0.9 2.7 2 0 0 2 2 2 2 Ataxin-2 C-terminal region DUF1284 PF06935.11 ORY89052.1 - 0.24 11.8 1.5 0.88 10.0 1.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) CENP-F_leu_zip PF10473.9 ORY89052.1 - 2.9 7.9 63.8 0.82 9.7 12.9 5.9 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MCPVI PF02993.14 ORY89052.1 - 7.4 6.3 14.8 0.5 10.2 1.0 4.5 4 0 0 4 4 4 0 Minor capsid protein VI Pox_A_type_inc PF04508.12 ORY89052.1 - 7.8 6.5 8.7 2.3 8.2 0.1 3.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Y_phosphatase2 PF03162.13 ORY89053.1 - 1.4e-34 119.1 0.0 1.7e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family AAA PF00004.29 ORY89054.1 - 3.9e-31 108.2 0.0 6.3e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY89054.1 - 2e-07 31.4 0.4 2.8e-06 27.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY89054.1 - 3.2e-07 30.9 0.0 8.2e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 ORY89054.1 - 6.8e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORY89054.1 - 2.3e-05 25.0 0.0 4.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY89054.1 - 9e-05 22.7 0.0 0.00026 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY89054.1 - 9.6e-05 22.0 2.0 0.22 11.0 0.0 2.7 2 1 1 3 3 3 2 AAA domain ATPase_2 PF01637.18 ORY89054.1 - 0.0002 21.3 0.1 0.09 12.7 0.1 2.2 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORY89054.1 - 0.0004 20.4 0.0 0.00072 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORY89054.1 - 0.00083 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY89054.1 - 0.0015 18.5 0.1 0.005 16.8 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 ORY89054.1 - 0.0033 17.2 0.1 0.012 15.4 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY89054.1 - 0.0034 17.4 0.1 0.0078 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY89054.1 - 0.0034 17.7 0.0 0.0079 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 ORY89054.1 - 0.0039 17.2 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ORY89054.1 - 0.0041 17.6 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_11 PF13086.6 ORY89054.1 - 0.0053 16.6 0.1 0.0053 16.6 0.1 1.9 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.13 ORY89054.1 - 0.0053 15.9 0.0 0.034 13.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY89054.1 - 0.0053 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 ORY89054.1 - 0.0056 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY89054.1 - 0.006 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Cytidylate_kin PF02224.18 ORY89054.1 - 0.0063 16.3 0.1 0.014 15.1 0.0 1.6 2 0 0 2 2 1 1 Cytidylate kinase Viral_helicase1 PF01443.18 ORY89054.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 ORY89054.1 - 0.022 14.0 0.2 0.046 12.9 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain Rad51 PF08423.11 ORY89054.1 - 0.031 13.5 0.2 1 8.6 0.2 2.2 1 1 0 2 2 2 0 Rad51 Mg_chelatase PF01078.21 ORY89054.1 - 0.043 13.2 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 ORY89054.1 - 0.047 13.2 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 ORY89054.1 - 0.056 13.8 0.0 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORY89054.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 ORY89054.1 - 0.086 13.3 0.0 0.22 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 ORY89054.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORY89054.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 ORY89054.1 - 0.13 11.7 0.0 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 ORY89054.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 ORY89054.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3678 PF12435.8 ORY89054.1 - 0.79 9.2 4.2 2.1 7.8 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Mt_ATP-synt_B PF05405.14 ORY89055.1 - 7.4e-45 152.5 2.4 9.1e-45 152.2 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TSC22 PF01166.18 ORY89055.1 - 0.014 15.7 0.2 0.041 14.2 0.2 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family Fib_alpha PF08702.10 ORY89055.1 - 0.78 9.9 2.6 1.2 9.3 2.5 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Mur_ligase_M PF08245.12 ORY89056.1 - 0.0001 22.3 0.0 0.0044 17.0 0.0 2.6 1 1 1 2 2 2 2 Mur ligase middle domain PCI PF01399.27 ORY89057.1 - 0.039 14.5 0.1 0.08 13.5 0.0 1.5 2 0 0 2 2 2 0 PCI domain AMP-binding PF00501.28 ORY89058.1 - 1.3e-84 284.3 0.0 1.6e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY89058.1 - 4.4e-14 53.2 0.7 1.4e-13 51.6 0.8 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Myb_DNA-binding PF00249.31 ORY89059.1 - 6.7e-27 93.4 5.0 3.7e-10 39.8 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY89059.1 - 2.5e-20 72.5 12.0 1.6e-08 34.7 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 ORY89059.1 - 0.49 10.6 2.4 1.6 9.0 0.1 2.6 3 0 0 3 3 3 0 SANT/Myb-like domain of DAMP1 DUF4554 PF15091.6 ORY89059.1 - 2.1 7.2 10.9 4.2 6.2 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Q_salvage PF10343.9 ORY89060.1 - 1.9e-16 60.5 0.0 6.2e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 Potential Queuosine, Q, salvage protein family DUF5308 PF17233.2 ORY89060.1 - 6.3 7.0 12.3 1.6 8.9 0.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) zf-CCHC PF00098.23 ORY89061.1 - 1.4e-11 43.9 8.8 3.5e-08 33.2 2.3 3.9 5 0 0 5 5 5 2 Zinc knuckle zf-CCHC_3 PF13917.6 ORY89061.1 - 1.5e-05 24.9 4.4 0.0003 20.7 0.7 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 ORY89061.1 - 0.035 13.9 1.6 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 ORY89061.1 - 0.28 11.1 5.2 4.6 7.2 1.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 ORY89062.1 - 0.26 11.5 2.8 0.59 10.3 2.8 1.7 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_S2 PF00318.20 ORY89063.1 - 7.1e-27 94.0 0.3 5.8e-15 55.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORY89063.1 - 7.6e-05 24.0 2.8 0.00015 23.0 2.8 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Lipoprotein_19 PF13617.6 ORY89064.1 - 0.15 11.8 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 YnbE-like lipoprotein Ferric_reduct PF01794.19 ORY89065.1 - 4.9e-20 71.9 10.4 1.3e-19 70.5 10.4 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY89065.1 - 6.5e-13 49.1 0.0 4e-10 40.0 0.0 2.6 3 0 0 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 ORY89065.1 - 0.0012 19.5 0.1 0.069 13.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 ORY89065.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.6 1 1 0 1 1 1 0 FAD-binding domain Ctr PF04145.15 ORY89066.1 - 2.5e-31 109.3 1.1 3.2e-31 108.9 1.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Toxin_ToxA PF11584.8 ORY89067.1 - 0.034 14.1 0.0 0.076 13.0 0.0 1.5 1 1 0 1 1 1 0 Proteinaceous host-selective toxin ToxA F-box-like PF12937.7 ORY89068.1 - 0.00012 21.8 0.1 0.00033 20.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like NIF PF03031.18 ORY89069.1 - 1.1e-56 190.9 0.3 1.3e-56 190.7 0.3 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORY89069.1 - 0.0026 18.2 0.1 0.032 14.6 0.0 2.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY89069.1 - 0.0099 16.2 0.0 2.4 8.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY89069.1 - 0.15 12.2 0.1 0.48 10.5 0.1 1.6 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase F_bP_aldolase PF01116.20 ORY89070.1 - 0.23 10.9 0.0 2.7 7.4 0.0 2.1 1 1 0 2 2 2 0 Fructose-bisphosphate aldolase class-II SNARE PF05739.19 ORY89071.1 - 7.2e-12 45.1 0.0 1.5e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 ORY89071.1 - 1.7e-05 23.9 0.7 7.5e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin-18_N PF10496.9 ORY89071.1 - 0.00024 21.3 1.4 0.00049 20.3 0.1 2.2 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Syntaxin PF00804.25 ORY89071.1 - 0.0012 18.5 9.7 0.0062 16.2 0.3 2.6 2 1 1 3 3 3 2 Syntaxin DUF16 PF01519.16 ORY89071.1 - 0.065 13.7 4.9 0.11 13.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 zf-C4H2 PF10146.9 ORY89071.1 - 0.085 13.2 0.5 0.21 11.9 0.2 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein SlyX PF04102.12 ORY89071.1 - 0.14 12.8 3.6 6.4 7.5 0.2 3.0 2 0 0 2 2 2 0 SlyX Syntaxin_2 PF14523.6 ORY89071.1 - 0.34 11.3 10.1 1.9 8.9 3.7 3.1 3 0 0 3 3 3 0 Syntaxin-like protein FlxA PF14282.6 ORY89071.1 - 0.89 9.6 12.9 0.029 14.4 5.3 2.2 2 0 0 2 2 2 0 FlxA-like protein NPV_P10 PF05531.12 ORY89071.1 - 1.6 9.2 6.7 3 8.4 1.2 3.1 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 ORY89071.1 - 4 7.6 6.5 5.2 7.3 1.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 ORY89071.1 - 5.8 7.2 5.9 13 6.1 0.6 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain Macoilin PF09726.9 ORY89073.1 - 0.16 10.5 18.2 0.24 9.9 18.2 1.2 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 ORY89073.1 - 1.9 7.7 14.3 3.8 6.8 14.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Inhibitor_I9 PF05922.16 ORY89074.1 - 7.2e-12 45.8 0.3 8.1e-12 45.6 0.3 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 zf-UBR PF02207.20 ORY89075.1 - 2.9e-14 53.0 13.7 2.9e-14 53.0 13.7 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 ORY89075.1 - 9e-10 38.2 0.0 3e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.9 ORY89075.1 - 0.015 14.8 0.0 0.05 13.1 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL Furin-like PF00757.20 ORY89076.1 - 0.69 9.8 50.4 0.017 15.0 24.4 3.7 2 1 1 3 3 3 0 Furin-like cysteine rich region TNFR_c6 PF00020.18 ORY89076.1 - 5.1 7.6 44.1 0.24 11.9 3.8 5.7 5 1 0 5 5 5 0 TNFR/NGFR cysteine-rich region Fer4 PF00037.27 ORY89077.1 - 6.1 6.8 8.7 5.9 6.9 0.4 4.2 3 0 0 3 3 3 0 4Fe-4S binding domain RabGAP-TBC PF00566.18 ORY89078.1 - 2.4e-54 184.3 0.0 4e-54 183.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain APG6_N PF17675.1 ORY89078.1 - 0.00024 21.6 8.8 0.00054 20.5 8.8 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 ORY89078.1 - 0.0032 17.4 2.5 0.0045 17.0 1.3 1.9 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 ORY89078.1 - 0.014 15.5 3.6 0.026 14.6 3.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding VGPC1_C PF16799.5 ORY89078.1 - 0.047 13.7 2.7 0.068 13.2 1.2 2.1 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Cnn_1N PF07989.11 ORY89078.1 - 0.049 13.8 3.0 0.16 12.2 3.0 1.9 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 ORY89078.1 - 0.05 13.8 6.9 0.27 11.4 7.0 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 ORY89078.1 - 0.067 13.3 7.8 0.11 12.5 7.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein SOGA PF11365.8 ORY89078.1 - 0.067 14.3 5.6 0.11 13.7 3.4 2.3 1 1 1 2 2 2 0 Protein SOGA RsbU_N PF08673.10 ORY89078.1 - 0.16 12.1 1.9 1.7 8.8 0.0 3.3 3 1 0 3 3 3 0 Phosphoserine phosphatase RsbU, N-terminal domain HAP1_N PF04849.13 ORY89078.1 - 0.18 11.0 8.5 0.2 10.8 6.4 1.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DivIVA PF05103.13 ORY89078.1 - 0.4 10.8 3.9 0.75 9.9 3.9 1.4 1 0 0 1 1 1 0 DivIVA protein DivIC PF04977.15 ORY89078.1 - 0.47 10.2 7.2 5.2 6.9 1.0 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF724 PF05266.14 ORY89078.1 - 2.4 8.0 7.1 3.5 7.4 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) LPP PF04728.13 ORY89078.1 - 4.5 7.7 5.6 0.76 10.2 0.9 2.0 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PRA-PH PF01503.17 ORY89081.1 - 5.9 7.4 6.3 0.73 10.3 1.9 1.8 2 0 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Voltage_CLC PF00654.20 ORY89082.1 - 1.7e-90 303.9 27.0 1.7e-90 303.9 27.0 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY89082.1 - 3e-09 37.2 0.0 0.00024 21.5 0.0 2.7 2 0 0 2 2 2 2 CBS domain GGDEF_2 PF17853.1 ORY89082.1 - 0.072 13.4 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 GGDEF-like domain Defensin_RK-1 PF17860.1 ORY89082.1 - 0.075 13.5 0.3 0.18 12.3 0.3 1.6 1 0 0 1 1 1 0 RK-1-like defensin Furin-like_2 PF15913.5 ORY89083.1 - 9.5e-06 25.7 25.7 3e-05 24.1 8.0 3.6 2 1 1 3 3 3 2 Furin-like repeat, cysteine-rich FOG_N PF15888.5 ORY89083.1 - 2.1 8.7 9.9 12 6.3 0.0 4.1 4 0 0 4 4 4 0 Folded gastrulation N-terminus GRDP-like PF07173.12 ORY89084.1 - 1.8e-24 87.0 0.1 9.5e-17 62.0 0.0 3.2 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like GRDP-like PF07173.12 ORY89085.1 - 3.6e-23 82.8 0.0 1.5e-15 58.1 0.0 3.2 2 1 1 3 3 3 3 Glycine-rich domain-containing protein-like BPL_LplA_LipB PF03099.19 ORY89086.1 - 0.00023 21.1 0.2 0.0013 18.6 0.2 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF4964 PF16334.5 ORY89086.1 - 0.037 13.6 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4964) zf-CCCH_4 PF18044.1 ORY89087.1 - 4.8e-08 32.6 8.5 0.00096 18.9 0.5 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 ORY89087.1 - 6.4e-08 33.3 5.7 0.00043 20.9 0.6 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 ORY89087.1 - 1.8e-05 24.9 0.3 3.1e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 ORY89087.1 - 4e-05 23.4 8.2 0.0054 16.6 1.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 ORY89087.1 - 0.0064 16.9 3.5 0.0064 16.9 3.5 2.3 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 ORY89087.1 - 0.044 13.9 16.2 0.12 12.5 2.7 2.3 2 0 0 2 2 2 0 Zinc finger domain F-box-like PF12937.7 ORY89088.1 - 2.3e-05 24.2 0.3 6.4e-05 22.8 0.3 1.8 1 0 0 1 1 1 1 F-box-like Toxin_ToxA PF11584.8 ORY89089.1 - 0.038 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Ctr PF04145.15 ORY89090.1 - 2.1e-31 109.6 1.2 2.6e-31 109.2 1.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 ORY89091.1 - 1.3e-19 70.5 10.4 1.3e-19 70.5 10.4 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY89091.1 - 6.3e-13 49.1 0.0 3.7e-10 40.1 0.0 2.5 3 0 0 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 ORY89091.1 - 0.001 19.7 0.1 0.061 14.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 ORY89091.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Furin-like_2 PF15913.5 ORY89092.1 - 0.0026 17.9 15.8 0.0026 17.9 15.8 10.6 3 2 9 12 12 12 8 Furin-like repeat, cysteine-rich HATPase_c PF02518.26 ORY89096.1 - 2.4e-29 102.1 0.0 4.2e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY89096.1 - 3.5e-23 81.9 0.1 1.2e-22 80.2 0.1 2.0 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 ORY89096.1 - 3.5e-13 49.6 0.4 2.5e-12 46.9 0.2 2.5 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 ORY89096.1 - 8.3e-11 41.8 0.0 3.3e-10 39.8 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ORY89096.1 - 0.00056 20.1 0.0 0.0099 16.1 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 ORY89096.1 - 0.0047 17.2 0.0 1.3 9.4 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 ORY89096.1 - 0.0077 16.2 0.0 0.026 14.5 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 ORY89096.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY89097.1 - 5.7e-30 104.1 0.1 2.3e-29 102.2 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY89097.1 - 3.4e-26 91.6 0.2 8.9e-26 90.3 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_3 PF08447.12 ORY89097.1 - 4.9e-17 62.0 0.3 2.9e-16 59.5 0.3 2.1 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 ORY89097.1 - 1.2e-12 47.6 0.0 3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY89097.1 - 4.7e-09 36.5 0.7 2.9e-05 24.3 0.0 3.4 4 0 0 4 4 4 2 PAS fold PAS PF00989.25 ORY89097.1 - 2.8e-08 33.8 0.0 1.1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 ORY89097.1 - 0.00011 22.4 0.0 0.0017 18.6 0.0 2.7 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.6 ORY89097.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Gemini_mov PF01708.16 ORY89098.1 - 0.08 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF4171 PF13775.6 ORY89098.1 - 1.8 9.0 16.3 0.53 10.7 11.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4171) FoP_duplication PF13865.6 ORY89099.1 - 0.55 10.8 7.7 0.94 10.1 7.7 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Glycophorin_A PF01102.18 ORY89100.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Adeno_E3_CR2 PF02439.15 ORY89100.1 - 0.04 13.7 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Amnionless PF14828.6 ORY89100.1 - 0.04 12.7 0.2 0.058 12.2 0.2 1.1 1 0 0 1 1 1 0 Amnionless YajC PF02699.15 ORY89100.1 - 0.043 13.7 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit RIFIN PF02009.16 ORY89100.1 - 0.053 13.4 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Rifin VSP PF03302.13 ORY89100.1 - 0.088 11.7 0.2 0.15 10.9 0.2 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein EphA2_TM PF14575.6 ORY89100.1 - 0.095 13.6 0.0 0.17 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.11 ORY89100.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Stevor PF17410.2 ORY89100.1 - 0.26 10.8 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CYYR1 PF10873.8 ORY89100.1 - 0.73 10.3 5.7 1.4 9.4 0.1 2.6 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Chlam_PMP PF02415.17 ORY89100.1 - 9 7.0 9.0 0.26 11.8 1.0 2.7 1 1 1 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Ank_4 PF13637.6 ORY89103.1 - 8.9e-13 48.5 0.2 2.7e-09 37.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY89103.1 - 1.8e-11 43.1 0.4 7.5e-07 29.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY89103.1 - 2.2e-10 41.0 0.1 6.8e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY89103.1 - 3.2e-09 36.8 2.2 5.3e-06 26.6 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 ORY89103.1 - 1e-07 32.1 0.4 0.00041 20.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ribonuclease_T2 PF00445.18 ORY89105.1 - 2.7e-36 125.5 1.1 4e-36 125.0 1.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family zf-RING_13 PF17977.1 ORY89105.1 - 0.057 13.6 0.4 8.5 6.6 0.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribonuclease_T2 PF00445.18 ORY89106.1 - 1.3e-39 136.3 0.2 1.9e-39 135.8 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family DUF2574 PF10836.8 ORY89106.1 - 0.12 12.3 2.0 0.33 10.8 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) DIOX_N PF14226.6 ORY89107.1 - 2.4e-25 89.6 0.0 4.9e-25 88.6 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY89107.1 - 1.8e-18 66.9 0.0 3.2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rhodanese PF00581.20 ORY89108.1 - 9.9e-14 51.8 0.0 1.4e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 ORY89109.1 - 1.3e-18 67.4 0.0 1.7e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain UPRTase PF14681.6 ORY89110.1 - 5.4e-64 215.4 0.0 6.6e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY89110.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain DUF3263 PF11662.8 ORY89110.1 - 0.077 12.9 0.1 5.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3263) GCP_N_terminal PF17681.1 ORY89112.1 - 0.024 14.3 1.1 0.032 13.9 1.1 1.1 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Nic96 PF04097.14 ORY89113.1 - 2.2e-202 673.9 0.5 2.6e-202 673.6 0.5 1.1 1 0 0 1 1 1 1 Nup93/Nic96 bZIP_1 PF00170.21 ORY89114.1 - 0.0031 17.6 3.1 0.84 9.8 1.0 2.6 2 0 0 2 2 2 2 bZIP transcription factor Hemerythrin PF01814.23 ORY89114.1 - 0.16 12.6 3.1 0.51 11.0 0.0 2.5 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Thyroglob_assoc PF16597.5 ORY89114.1 - 2.3 8.6 6.3 0.2 12.0 0.5 2.2 2 0 0 2 2 2 0 Thyroglobulin_1 repeat associated disordered domain F-box-like PF12937.7 ORY89115.1 - 5.8e-05 22.9 1.2 9e-05 22.3 0.2 1.9 2 0 0 2 2 2 1 F-box-like PelD_GGDEF PF16963.5 ORY89115.1 - 0.013 15.3 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 PelD GGDEF domain LigB PF02900.18 ORY89118.1 - 4.4e-36 124.4 0.0 5.5e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase ABC_membrane PF00664.23 ORY89119.1 - 1.6e-49 169.0 27.8 9.8e-25 87.7 3.7 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY89119.1 - 5.2e-40 137.1 0.0 6.2e-22 78.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY89119.1 - 2.9e-14 53.1 0.0 5.3e-08 32.6 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ORY89119.1 - 5.3e-05 22.9 0.0 0.0068 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY89119.1 - 0.00079 19.1 1.2 1.2 8.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 ORY89119.1 - 0.00086 18.4 0.2 1.3 8.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 ORY89119.1 - 0.0025 18.1 1.7 2.9 8.2 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 ORY89119.1 - 0.0054 16.6 1.5 6.4 6.5 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ORY89119.1 - 0.016 15.6 0.5 7.6 7.0 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY89119.1 - 0.068 13.6 3.9 10 6.5 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain DEAD PF00270.29 ORY89119.1 - 0.084 12.6 0.2 8.9 6.0 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 ORY89119.1 - 0.22 11.6 0.3 17 5.5 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY89119.1 - 0.5 10.8 12.2 5.8 7.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 ORY89119.1 - 0.51 9.9 6.0 0.12 12.0 0.8 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 ORY89119.1 - 0.64 9.9 2.3 6.3 6.7 0.2 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 ORY89119.1 - 0.67 10.5 3.4 25 5.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY89119.1 - 1.3 9.2 4.2 5.1 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 ORY89119.1 - 8.4 6.4 6.1 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain NACHT PF05729.12 ORY89119.1 - 9.4 6.1 7.6 3.6 7.5 0.1 3.4 3 0 0 3 3 3 0 NACHT domain DUF4551 PF15087.6 ORY89120.1 - 6.5 5.5 9.0 8.2 5.1 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CBS PF00571.28 ORY89121.1 - 6.5e-21 74.5 4.0 1.5e-06 28.5 0.0 5.0 5 1 0 5 5 5 3 CBS domain SOG2 PF10428.9 ORY89121.1 - 0.13 11.4 15.2 0.014 14.6 10.0 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein Atg14 PF10186.9 ORY89122.1 - 8.9e-15 54.6 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Spectrin PF00435.21 ORY89122.1 - 0.034 14.6 4.1 0.092 13.2 4.1 1.7 1 0 0 1 1 1 0 Spectrin repeat OmpH PF03938.14 ORY89122.1 - 0.27 11.6 6.4 0.53 10.6 6.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 ORY89122.1 - 0.58 10.2 13.9 1.7 8.7 13.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein VPS38 PF17649.1 ORY89122.1 - 0.63 8.8 6.3 0.65 8.8 0.2 2.8 3 0 0 3 3 3 0 Vacuolar protein sorting 38 CorA PF01544.18 ORY89122.1 - 1.9 7.7 5.5 3.3 7.0 5.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SKG6 PF08693.10 ORY89122.1 - 2.2 7.7 4.3 5 6.6 4.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Prefoldin_2 PF01920.20 ORY89122.1 - 3.3 7.7 11.3 0.32 11.0 5.8 2.0 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 ORY89122.1 - 4.2 7.8 4.5 16 6.0 0.8 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 ORY89122.1 - 4.7 6.5 5.8 8.4 5.6 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4122 PF13498.6 ORY89122.1 - 4.8 6.8 8.6 3.1 7.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4122) HNH_2 PF13391.6 ORY89123.1 - 3.9e-05 23.7 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease AHH PF14412.6 ORY89123.1 - 0.11 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH PIG-L PF02585.17 ORY89126.1 - 0.31 11.7 1.5 5.2 7.7 0.0 2.7 2 1 0 2 2 2 0 GlcNAc-PI de-N-acetylase Pam16 PF03656.13 ORY89127.1 - 1.1e-21 77.2 1.1 1.1e-21 77.2 1.1 1.5 1 1 1 2 2 2 1 Pam16 RIFIN PF02009.16 ORY89127.1 - 0.013 15.4 2.3 0.015 15.2 2.3 1.0 1 0 0 1 1 1 0 Rifin Med4 PF10018.9 ORY89128.1 - 7.5e-12 45.3 0.6 1.4e-11 44.5 0.6 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 SOAR PF16533.5 ORY89128.1 - 0.0031 17.5 0.0 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 STIM1 Orai1-activating region Trimer_CC PF08954.11 ORY89128.1 - 0.0094 15.5 0.0 0.0094 15.5 0.0 2.4 2 0 0 2 2 2 1 Trimerisation motif Nnf1 PF03980.14 ORY89128.1 - 0.03 14.7 3.1 0.078 13.4 0.6 2.3 2 1 0 2 2 2 0 Nnf1 Seryl_tRNA_N PF02403.22 ORY89128.1 - 0.086 13.1 2.7 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MRPL52 PF18699.1 ORY89128.1 - 0.46 10.7 5.9 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 Mitoribosomal protein mL52 eIF_4EBP PF05456.11 ORY89128.1 - 0.74 9.8 6.2 0.13 12.2 2.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CDV3 PF15359.6 ORY89129.1 - 0.14 12.7 0.5 0.25 11.8 0.1 1.7 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 XPG_I_2 PF12813.7 ORY89130.1 - 2.3e-07 30.5 0.0 1.3e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing XPG_I PF00867.18 ORY89130.1 - 0.00054 20.2 0.0 0.00093 19.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region PAN_4 PF14295.6 ORY89131.1 - 3e-05 23.9 2.7 3e-05 23.9 2.7 2.1 2 0 0 2 2 2 1 PAN domain ArfGap PF01412.18 ORY89134.1 - 5.2e-30 103.9 1.8 1.6e-29 102.3 0.5 1.8 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 ORY89134.1 - 0.097 12.8 1.7 0.29 11.3 1.7 1.8 1 1 0 1 1 1 0 B-box zinc finger zf-RRN7 PF11781.8 ORY89134.1 - 0.13 11.9 2.3 0.21 11.3 2.3 1.2 1 0 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 HigB-like_toxin PF05015.13 ORY89136.1 - 0.00066 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RelE-like toxin of type II toxin-antitoxin system HigB DUF1843 PF08898.10 ORY89136.1 - 0.25 11.9 4.8 68 4.1 0.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) NAD_binding_1 PF00175.21 ORY89137.1 - 5.1e-27 94.7 0.0 8.3e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY89137.1 - 2.2e-19 69.6 0.0 4.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY89137.1 - 0.0032 17.6 0.0 0.067 13.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_5 PF07994.12 ORY89138.1 - 8.2e-145 482.2 0.0 9.6e-145 482.0 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ORY89138.1 - 2e-45 153.5 0.0 4e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase GGDEF_2 PF17853.1 ORY89138.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 GGDEF-like domain Pyr_redox_2 PF07992.14 ORY89139.1 - 1.7e-48 165.4 2.9 2.2e-48 165.0 2.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 ORY89139.1 - 6.2e-15 54.9 0.0 1.6e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 ORY89139.1 - 3.4e-13 49.9 1.0 1.1e-08 35.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY89139.1 - 7.9e-09 35.2 0.1 1.1e-05 24.8 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY89139.1 - 1.4e-06 27.7 0.1 0.012 14.8 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Reductase_C PF14759.6 ORY89139.1 - 9.8e-05 22.8 0.0 0.00025 21.6 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal NAD_binding_7 PF13241.6 ORY89139.1 - 0.00019 21.9 0.2 0.058 13.8 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 ORY89139.1 - 0.042 13.1 0.0 0.62 9.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF3140 PF11338.8 ORY89140.1 - 3.1e-34 117.3 0.9 3.8e-34 117.0 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF1843 PF08898.10 ORY89140.1 - 0.05 14.1 0.7 0.081 13.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF4724 PF15852.5 ORY89140.1 - 0.18 12.3 0.3 0.18 12.3 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) TMA7 PF09072.10 ORY89140.1 - 0.63 10.9 3.6 1.6 9.6 3.6 1.9 1 1 0 1 1 1 0 Translation machinery associated TMA7 F-box-like PF12937.7 ORY89141.1 - 0.00023 21.0 1.0 0.00041 20.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like SelB-wing_1 PF09105.10 ORY89141.1 - 0.041 13.9 0.1 17 5.5 0.0 2.9 3 0 0 3 3 3 0 Elongation factor SelB, winged helix F-box-like PF12937.7 ORY89142.1 - 0.00018 21.3 0.1 0.00056 19.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY89142.1 - 0.11 12.9 0.4 7.6 7.1 0.5 2.7 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Pkinase PF00069.25 ORY89144.1 - 3.8e-67 226.4 0.1 5e-67 226.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89144.1 - 3.7e-18 65.8 0.0 5.2e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY89144.1 - 2.3e-07 31.0 0.0 4.4e-06 26.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY89144.1 - 0.0077 15.0 0.0 0.015 14.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 ORY89144.1 - 0.014 15.0 0.1 0.014 15.0 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 ORY89144.1 - 0.015 14.6 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 ORY89145.1 - 1.3e-52 175.7 1.2 2.1e-16 59.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CTP_transf_like PF01467.26 ORY89146.1 - 1.2e-06 28.7 0.4 2e-06 28.1 0.4 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Pre-PUA PF17832.1 ORY89147.1 - 1e-21 77.4 0.6 4.9e-14 52.8 0.1 2.3 2 0 0 2 2 2 2 Pre-PUA-like domain PUA PF01472.20 ORY89147.1 - 4.2e-14 52.3 0.0 8.2e-14 51.3 0.0 1.5 1 1 0 1 1 1 1 PUA domain APH PF01636.23 ORY89150.1 - 6.8e-06 26.2 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 ORY89150.1 - 1.7e-05 24.4 0.1 2.7e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89150.1 - 0.045 13.0 0.1 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 ORY89150.1 - 0.22 10.8 0.1 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Inos-1-P_synth PF01658.17 ORY89152.1 - 9.5e-14 51.6 0.0 1.1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase NAD_binding_5 PF07994.12 ORY89152.1 - 3.1e-05 23.5 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Asp_decarbox PF02261.16 ORY89152.1 - 0.055 13.4 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Aspartate decarboxylase COG2 PF06148.11 ORY89153.1 - 6.1e-27 94.3 0.9 1.3e-26 93.2 0.9 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 ORY89153.1 - 3.5e-26 92.0 0.3 1.2e-25 90.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Spc7 PF08317.11 ORY89153.1 - 0.022 13.7 0.9 0.04 12.8 0.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein YabA PF06156.13 ORY89153.1 - 0.064 13.9 0.9 0.25 12.0 0.3 2.2 2 0 0 2 2 2 0 Initiation control protein YabA Vps51 PF08700.11 ORY89153.1 - 0.11 12.6 0.3 1.4 9.0 0.2 2.7 1 1 0 1 1 1 0 Vps51/Vps67 Dor1 PF04124.12 ORY89153.1 - 0.17 10.5 1.8 0.26 9.9 0.7 1.7 2 0 0 2 2 2 0 Dor1-like family COG5 PF10392.9 ORY89153.1 - 0.25 11.5 6.0 1.6 8.9 1.8 3.2 3 1 0 3 3 3 0 Golgi transport complex subunit 5 APG6_N PF17675.1 ORY89153.1 - 0.96 10.0 8.0 0.079 13.5 2.0 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Cwf_Cwc_15 PF04889.12 ORY89155.1 - 2 8.1 17.0 1.4 8.6 15.5 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF952 PF06108.12 ORY89156.1 - 9.5e-19 67.2 0.0 1.7e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Mito_carr PF00153.27 ORY89157.1 - 3e-43 145.7 1.1 3.5e-14 52.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 ORY89157.1 - 0.022 15.1 0.1 0.39 11.1 0.0 2.4 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Nucleoporin_N PF08801.11 ORY89158.1 - 2.9e-58 197.6 0.0 4.5e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ORY89158.1 - 7.3e-43 147.2 0.0 1.8e-42 145.9 0.0 1.4 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Chloroplast_duf PF14476.6 ORY89158.1 - 0.064 12.2 0.0 0.24 10.3 0.0 1.9 2 0 0 2 2 2 0 Petal formation-expressed Methyltransf_34 PF11312.8 ORY89159.1 - 5.8e-62 209.7 0.0 1.4e-61 208.5 0.0 1.5 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase CN_hydrolase PF00795.22 ORY89161.1 - 4.5e-33 114.7 0.0 5.2e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SNF2_N PF00176.23 ORY89162.1 - 2e-68 230.7 0.0 5.1e-68 229.3 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain HAND PF09110.11 ORY89162.1 - 1.6e-31 109.4 1.0 1.6e-31 109.4 1.0 3.5 3 1 0 3 3 2 1 HAND SLIDE PF09111.10 ORY89162.1 - 2.1e-26 92.2 2.7 2.1e-26 92.2 0.2 2.3 2 0 0 2 2 2 1 SLIDE Helicase_C PF00271.31 ORY89162.1 - 9.4e-18 64.6 0.0 4.1e-17 62.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY89162.1 - 1.4e-07 31.7 0.0 6.6e-07 29.5 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 ORY89162.1 - 1.5e-05 25.1 0.0 0.29 11.3 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 ORY89162.1 - 0.00015 21.0 0.0 0.00044 19.5 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DBINO PF13892.6 ORY89162.1 - 0.0016 18.8 3.1 0.0016 18.8 3.1 3.5 4 0 0 4 4 3 1 DNA-binding domain DUF1086 PF06461.11 ORY89162.1 - 0.0062 16.4 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) AAA_14 PF13173.6 ORY89162.1 - 0.014 15.4 0.0 0.049 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Nexin_C PF08628.12 ORY89162.1 - 0.036 14.6 0.3 2.3 8.8 0.3 2.9 2 0 0 2 2 2 0 Sorting nexin C terminal SLIDE PF09111.10 ORY89163.1 - 4.2e-28 97.7 0.1 4.9e-28 97.4 0.1 1.0 1 0 0 1 1 1 1 SLIDE Myb_DNA-binding PF00249.31 ORY89163.1 - 0.014 15.5 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain EF-1_beta_acid PF10587.9 ORY89163.1 - 0.024 15.1 0.6 0.024 15.1 0.6 1.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region NAD_binding_5 PF07994.12 ORY89164.1 - 4.3e-144 479.8 0.0 5e-144 479.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ORY89164.1 - 2.1e-45 153.5 0.0 4e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase GST_C PF00043.25 ORY89165.1 - 6.8e-10 39.0 0.0 1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY89165.1 - 6.2e-08 32.7 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY89165.1 - 2.1e-05 24.4 0.2 4.2e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY89165.1 - 0.004 17.5 0.0 0.0077 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY89165.1 - 0.0092 16.3 0.0 0.052 13.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain FUN14 PF04930.15 ORY89166.1 - 3.5e-18 65.8 4.4 5.3e-18 65.2 4.4 1.3 1 0 0 1 1 1 1 FUN14 family Pkinase PF00069.25 ORY89168.1 - 3.1e-61 207.1 0.0 3.7e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89168.1 - 2.7e-16 59.6 0.0 4.2e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY89168.1 - 3.5e-06 27.1 0.2 8.1e-05 22.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family APG5 PF04106.12 ORY89169.1 - 1.4e-52 178.6 0.0 2.6e-52 177.7 0.0 1.5 1 1 0 1 1 1 1 Autophagy protein Apg5 TPR_2 PF07719.17 ORY89170.1 - 4.4e-06 26.4 0.0 0.23 11.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY89170.1 - 4.6e-06 27.0 0.0 0.3 11.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY89170.1 - 4.7e-05 23.5 0.4 0.078 13.1 0.0 3.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY89170.1 - 5.2e-05 23.8 0.1 0.07 13.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY89170.1 - 8.7e-05 22.7 0.2 0.0084 16.4 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TAF1_subA PF14929.6 ORY89170.1 - 0.00021 20.8 0.1 0.00033 20.2 0.1 1.3 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_14 PF13428.6 ORY89170.1 - 0.0068 17.1 0.5 28 5.9 0.0 3.9 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY89170.1 - 0.029 14.6 0.0 14 6.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SMG1 PF15785.5 ORY89170.1 - 0.044 12.2 0.0 0.056 11.8 0.0 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Zn_clus PF00172.18 ORY89171.1 - 0.061 13.4 4.7 0.11 12.7 4.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C PF00043.25 ORY89172.1 - 4.4e-11 42.9 0.1 1.1e-10 41.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY89172.1 - 2.2e-09 37.6 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY89172.1 - 1.1e-08 35.2 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY89172.1 - 1.2e-06 28.5 0.0 1.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY89172.1 - 1.3e-06 28.5 0.0 3.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY89172.1 - 1.5e-05 25.2 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 ORY89172.1 - 0.094 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein UQ_con PF00179.26 ORY89173.1 - 3.1e-45 153.3 0.0 3.5e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme 2-oxoacid_dh PF00198.23 ORY89174.1 - 1.4e-50 171.9 0.0 3.6e-50 170.6 0.0 1.6 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY89174.1 - 3.1e-17 62.1 1.5 6.7e-17 61.1 1.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 ORY89174.1 - 7.4e-17 61.4 0.1 1.9e-16 60.1 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.6 ORY89174.1 - 5.4e-05 23.8 0.2 0.045 14.4 0.0 2.7 2 1 1 3 3 3 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 ORY89174.1 - 0.00018 21.3 0.4 0.014 15.2 0.0 3.1 3 0 0 3 3 3 1 Biotin-lipoyl like SPX PF03105.19 ORY89176.1 - 2.6 7.9 9.2 3.5 7.5 9.2 1.1 1 0 0 1 1 1 0 SPX domain Cep57_MT_bd PF06657.13 ORY89247.1 - 8.6e-22 77.4 1.1 8.6e-22 77.4 1.1 4.0 2 1 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 DUF3138 PF11336.8 ORY89247.1 - 0.22 10.1 0.6 0.44 9.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Fib_alpha PF08702.10 ORY89247.1 - 0.33 11.2 6.9 0.038 14.2 0.7 2.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HCMV_UL139 PF12507.8 ORY89247.1 - 0.82 10.1 11.3 1 9.8 0.1 3.6 3 0 0 3 3 3 0 Human Cytomegalovirus UL139 protein Nodulin_late PF07127.11 ORY89249.1 - 0.095 13.0 12.2 3.8 7.9 0.5 3.7 3 1 0 3 3 3 0 Late nodulin protein DUF2576 PF10845.8 ORY89249.1 - 2.4 7.9 5.2 21 4.8 0.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2576) Pinin_SDK_memA PF04696.13 ORY89250.1 - 0.012 15.7 5.1 0.012 15.7 5.1 3.8 3 1 0 3 3 3 0 pinin/SDK/memA/ protein conserved region Organ_specific PF10950.8 ORY89250.1 - 0.032 15.0 1.7 0.032 15.0 1.7 2.4 3 0 0 3 3 3 0 Organ specific protein DUF1501 PF07394.12 ORY89250.1 - 0.3 10.1 2.0 0.62 9.1 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF2956 PF11169.8 ORY89250.1 - 8.6 6.6 11.0 0.68 10.1 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) tRNA_U5-meth_tr PF05958.11 ORY89251.1 - 2.9e-16 59.4 0.0 1.9e-14 53.4 0.0 3.0 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 ORY89251.1 - 1.1e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 ORY89251.1 - 0.00019 20.9 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY89251.1 - 0.00028 20.5 0.0 0.00066 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY89251.1 - 0.00029 21.5 0.0 0.00079 20.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY89251.1 - 0.00061 20.4 0.0 0.0021 18.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY89251.1 - 0.00092 19.0 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PMSI1 PF15322.6 ORY89251.1 - 0.026 14.0 1.2 0.05 13.1 1.2 1.4 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Met_10 PF02475.16 ORY89251.1 - 0.063 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 ORY89251.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_2b PF00587.25 ORY89252.1 - 5.3e-37 127.5 0.1 1.1e-36 126.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORY89252.1 - 7.7e-15 55.1 4.9 1.4e-14 54.3 4.9 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.32 ORY89255.1 - 6.8e-15 55.2 13.4 0.025 15.4 0.1 7.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89255.1 - 3.6e-09 36.8 0.5 0.00016 21.9 0.0 4.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY89255.1 - 1.9e-07 30.4 0.2 9.8e-06 24.7 0.0 2.8 2 2 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Copper-bind PF00127.20 ORY89256.1 - 9.6e-05 22.8 0.0 0.00021 21.6 0.0 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cyclin PF08613.11 ORY89258.1 - 7.6e-09 36.1 0.0 1.4e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY89258.1 - 0.013 15.3 0.0 0.029 14.1 0.0 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain Phenol_monoox PF04663.12 ORY89258.1 - 0.88 9.8 2.9 6 7.1 0.3 2.6 2 0 0 2 2 2 0 Phenol hydroxylase conserved region PHP PF02811.19 ORY89259.1 - 6.3e-13 49.4 0.0 8.7e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 PHP domain Alg6_Alg8 PF03155.15 ORY89260.1 - 7.2e-164 546.3 26.1 8.5e-164 546.1 26.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SET PF00856.28 ORY89261.1 - 7.1e-11 42.8 0.1 1.3e-07 32.1 0.0 2.3 1 1 1 2 2 2 2 SET domain DUF4051 PF13260.6 ORY89261.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) GTP_EFTU PF00009.27 ORY89262.1 - 2.1e-18 66.5 0.0 1e-17 64.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY89262.1 - 1.3e-06 28.7 0.2 3.8e-06 27.2 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 ORY89262.1 - 0.00052 20.3 0.0 0.0014 18.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 ORY89262.1 - 0.0047 17.0 0.1 0.019 15.1 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ORY89262.1 - 0.055 13.7 0.1 3.4 7.9 0.0 2.8 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FMN_dh PF01070.18 ORY89263.1 - 7.7e-114 380.3 0.0 8.8e-114 380.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY89263.1 - 0.00083 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY89263.1 - 0.00088 18.4 0.1 0.0063 15.5 0.0 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 ORY89263.1 - 0.0014 18.0 0.0 0.71 9.1 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Jnk-SapK_ap_N PF09744.9 ORY89263.1 - 0.0034 17.6 0.1 0.0054 17.0 0.1 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 NMO PF03060.15 ORY89263.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase MFS_1 PF07690.16 ORY89264.1 - 4.4e-20 71.9 36.6 4.8e-20 71.8 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 ORY89264.1 - 0.82 9.9 5.0 8.3 6.7 2.4 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) DUF3245 PF11595.8 ORY89266.1 - 9.9e-09 35.8 7.8 9.9e-09 35.8 7.8 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3245) Clat_adaptor_s PF01217.20 ORY89267.1 - 2.4e-22 79.4 0.1 4.4e-22 78.6 0.1 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Binary_toxB_3 PF17476.2 ORY89267.1 - 0.048 13.9 0.1 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 WD40 PF00400.32 ORY89268.1 - 9.1e-30 102.3 16.5 9.4e-07 29.5 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat RRM_1 PF00076.22 ORY89268.1 - 2.7e-07 30.3 0.0 6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 ORY89268.1 - 1.6e-06 28.3 0.8 4.2e-05 23.8 0.2 3.5 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain NTF2 PF02136.20 ORY89268.1 - 8.6e-05 23.1 0.0 0.00026 21.6 0.0 1.8 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Nup160 PF11715.8 ORY89268.1 - 0.00048 18.9 1.0 0.0026 16.5 1.0 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 ORY89268.1 - 0.12 12.9 0.0 1.5 9.5 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain RAP1 PF07218.11 ORY89268.1 - 0.72 8.1 5.1 1.3 7.2 5.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PI3K_1B_p101 PF10486.9 ORY89268.1 - 7.5 4.2 8.2 19 2.9 8.2 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TANGO2 PF05742.12 ORY89270.1 - 1.3e-43 149.9 0.0 2.1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Transport and Golgi organisation 2 UDG PF03167.19 ORY89271.1 - 2.1e-21 76.5 0.0 3.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Zip PF02535.22 ORY89272.1 - 2.8e-65 220.8 6.8 3.2e-65 220.6 6.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Mob1_phocein PF03637.17 ORY89273.1 - 4e-65 219.0 0.0 5e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OCD_Mu_crystall PF02423.15 ORY89274.1 - 1.2e-33 116.5 0.3 3.8e-33 114.8 0.3 1.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 ORY89274.1 - 3.8e-05 23.8 0.0 6.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY89274.1 - 0.0082 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GATA PF00320.27 ORY89275.1 - 4.3e-14 51.8 3.1 6e-14 51.4 3.1 1.2 1 0 0 1 1 1 1 GATA zinc finger PNP_phzG_C PF10590.9 ORY89277.1 - 8.7e-21 73.7 2.4 1.6e-20 72.9 2.4 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 ORY89277.1 - 1.5e-12 47.5 0.0 3.7e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 ORY89277.1 - 0.01 16.4 0.0 0.017 15.7 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Mon1 PF03164.14 ORY89278.1 - 1.2e-116 390.1 0.0 1.4e-116 389.9 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 FAD_binding_7 PF03441.14 ORY89279.1 - 1.7e-72 243.2 2.3 2.5e-72 242.6 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY89279.1 - 4e-41 140.8 0.0 9.4e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase TFA2_Winged_2 PF18121.1 ORY89279.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Chromo PF00385.24 ORY89280.1 - 0.0047 16.8 1.8 0.009 15.9 1.8 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain 2Fe-2S_thioredx PF01257.19 ORY89282.1 - 6.8e-58 194.6 0.1 8.3e-58 194.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Sugar_tr PF00083.24 ORY89284.1 - 9.1e-85 285.2 26.1 1.1e-84 285.0 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY89284.1 - 2.8e-28 98.9 34.8 2.8e-28 98.9 34.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY89284.1 - 1.1 7.5 12.0 0.015 13.7 4.4 1.7 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_3_2 PF04550.12 ORY89284.1 - 1.3 9.6 7.0 3.6 8.2 0.7 3.5 3 0 0 3 3 3 0 Phage holin family 2 MFS_1 PF07690.16 ORY89285.1 - 6.5e-12 45.0 31.7 8.9e-12 44.6 30.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89285.1 - 3.1e-07 29.6 8.4 3.1e-07 29.6 8.4 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter UNC-93 PF05978.16 ORY89285.1 - 4.5e-07 29.7 3.6 4.5e-07 29.7 3.6 3.4 3 1 1 4 4 4 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORY89285.1 - 0.0033 16.4 5.0 0.005 15.7 0.7 2.6 2 1 1 3 3 3 1 MFS_1 like family Peptidase_U4 PF03419.13 ORY89285.1 - 0.5 9.6 8.9 0.081 12.2 2.4 2.3 2 0 0 2 2 2 0 Sporulation factor SpoIIGA SNF5 PF04855.12 ORY89286.1 - 5.8e-62 209.6 2.1 1.8e-60 204.7 2.1 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 S4 PF01479.25 ORY89287.1 - 4.2e-12 45.6 0.1 1e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 ORY89287.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 S4 domain DAO PF01266.24 ORY89288.1 - 8.5e-56 190.0 0.1 9.7e-56 189.8 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY89288.1 - 0.0013 18.9 0.1 0.0027 17.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY89288.1 - 0.022 14.0 0.2 0.045 13.0 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY89288.1 - 0.072 13.7 0.3 0.19 12.3 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY89288.1 - 0.12 11.6 0.2 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Thi4 family MARVEL PF01284.23 ORY89289.1 - 0.0028 17.7 15.7 0.0042 17.1 15.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain GMC_oxred_N PF00732.19 ORY89290.1 - 9.9e-43 146.6 0.3 4.3e-41 141.2 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY89290.1 - 4.6e-24 85.6 0.3 3.7e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY89290.1 - 1.2e-05 24.6 1.9 0.00022 20.4 1.3 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 ORY89290.1 - 0.0056 16.0 0.5 0.0096 15.2 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY89290.1 - 0.016 15.5 1.0 0.21 11.9 0.7 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY89290.1 - 0.017 14.3 0.1 0.036 13.3 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.14 ORY89290.1 - 0.082 12.1 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY89290.1 - 1 8.6 4.0 0.36 10.1 1.5 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase CRAL_TRIO PF00650.20 ORY89291.1 - 4.7e-37 127.2 0.4 6.8e-37 126.6 0.4 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY89291.1 - 7.1e-07 29.3 0.1 1.5e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY89291.1 - 3.7e-06 27.1 0.0 5.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3189 PF11385.8 ORY89291.1 - 0.00097 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3189) Glyco_hydro_31 PF01055.26 ORY89292.1 - 2.7e-135 452.0 5.6 5.6e-135 450.9 5.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 PRKCSH_1 PF13015.6 ORY89292.1 - 2.9e-31 108.2 0.2 6.6e-31 107.1 0.2 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Gal_mutarotas_2 PF13802.6 ORY89292.1 - 1.1e-20 73.8 0.5 4.5e-20 71.7 0.1 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like PRKCSH-like PF12999.7 ORY89292.1 - 4.4e-17 62.4 3.2 8.8e-17 61.4 3.2 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like DUF5110 PF17137.4 ORY89292.1 - 6.5e-09 35.9 0.0 1.9e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) PRKCSH PF07915.13 ORY89292.1 - 2.3e-08 34.9 3.5 5.8e-08 33.6 3.5 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Tektin PF03148.14 ORY89292.1 - 0.059 12.1 5.5 1.1 7.9 2.6 2.2 1 1 1 2 2 2 0 Tektin family TelA PF05816.11 ORY89292.1 - 0.44 9.6 3.4 0.71 8.9 3.4 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) DivIC PF04977.15 ORY89292.1 - 0.57 10.0 3.2 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Macoilin PF09726.9 ORY89292.1 - 4.9 5.6 6.8 7.6 5.0 6.8 1.1 1 0 0 1 1 1 0 Macoilin family SIP1 PF04938.12 ORY89293.1 - 5.2e-24 85.2 0.0 7.7e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DAGK_cat PF00781.24 ORY89294.1 - 3.1e-20 72.1 0.0 7.1e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Exo_endo_phos_2 PF14529.6 ORY89295.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Reprolysin_5 PF13688.6 ORY89295.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 LSM PF01423.22 ORY89296.1 - 1.8e-21 75.6 0.0 2.2e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY89296.1 - 0.004 17.3 0.0 0.0044 17.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.23 ORY89297.1 - 2e-18 66.4 0.5 2e-18 66.4 0.5 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY89297.1 - 0.00082 19.7 0.2 0.0023 18.3 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 ORY89297.1 - 0.003 17.6 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Terminase_4 PF05119.12 ORY89297.1 - 0.0032 17.9 0.0 0.62 10.5 0.0 2.1 1 1 0 2 2 2 2 Phage terminase, small subunit PfkB PF00294.24 ORY89298.1 - 9.1e-17 61.3 0.0 1.8e-16 60.3 0.0 1.4 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORY89298.1 - 0.0061 16.0 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase WD40 PF00400.32 ORY89299.1 - 3.5e-60 198.5 26.8 2.4e-09 37.6 0.0 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89299.1 - 3.8e-22 78.4 2.1 0.0008 19.7 0.0 5.5 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY89299.1 - 7.6e-09 34.7 5.9 0.042 12.5 0.0 5.0 4 2 0 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.12 ORY89299.1 - 2.9e-08 34.1 0.0 5.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 ORY89299.1 - 5.4e-06 25.6 0.0 0.16 10.9 0.0 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY89299.1 - 6.8e-06 26.1 0.0 0.0017 18.3 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORY89299.1 - 0.00085 19.2 0.4 0.77 9.8 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ORY89299.1 - 0.0025 17.2 0.0 2.3 7.5 0.0 2.6 3 0 0 3 3 3 2 WD40-like domain IKI3 PF04762.12 ORY89299.1 - 0.0044 15.1 0.1 0.0068 14.5 0.1 1.2 1 0 0 1 1 1 1 IKI3 family Aminotran_1_2 PF00155.21 ORY89300.1 - 1.4e-36 126.4 0.0 2.9e-33 115.5 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II DUF676 PF05057.14 ORY89301.1 - 0.00097 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 ORY89301.1 - 0.013 14.7 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 ORY89301.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 ORY89301.1 - 0.034 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 ORY89301.1 - 0.18 11.4 0.7 2.3 7.8 0.7 2.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold YrhK PF14145.6 ORY89302.1 - 0.028 14.3 0.2 0.088 12.7 0.2 1.8 1 0 0 1 1 1 0 YrhK-like protein ABC_export PF16962.5 ORY89302.1 - 5 5.5 9.2 0.11 10.9 0.7 1.9 1 1 1 2 2 2 0 Putative ABC exporter Aa_trans PF01490.18 ORY89303.1 - 3.4e-36 124.8 22.0 4.2e-36 124.5 22.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF373 PF04123.13 ORY89303.1 - 1.3 8.4 10.1 0.13 11.7 0.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Spore_permease PF03845.13 ORY89303.1 - 4.2 6.1 19.1 0.047 12.5 8.1 2.8 2 2 0 2 2 2 0 Spore germination protein DNA_binding_1 PF01035.20 ORY89304.1 - 1.5e-22 79.5 3.6 3.9e-22 78.2 3.6 1.6 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain AA_permease PF00324.21 ORY89305.1 - 3.6e-105 352.3 37.2 4.4e-105 352.0 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY89305.1 - 4.1e-21 75.3 42.1 5.7e-21 74.8 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease BamHI PF02923.15 ORY89305.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease BamHI 2-Hacid_dh_C PF02826.19 ORY89306.1 - 2.2e-42 144.4 0.1 4.2e-41 140.2 0.1 2.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY89306.1 - 7.3e-05 22.4 0.0 0.0002 21.1 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain TadZ_N PF16968.5 ORY89306.1 - 0.0049 16.6 0.6 0.01 15.5 0.1 1.7 2 0 0 2 2 2 1 Pilus assembly protein TadZ N-terminal NAD_binding_2 PF03446.15 ORY89306.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY89306.1 - 0.076 13.6 0.1 2.1 9.0 0.1 2.6 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent XdhC_C PF13478.6 ORY89306.1 - 0.076 13.5 0.0 0.23 12.0 0.0 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain PhyH PF05721.13 ORY89307.1 - 2.9e-24 86.5 0.0 4.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PhyH PF05721.13 ORY89308.1 - 3.6e-26 92.7 0.1 5.2e-26 92.2 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3253 PF11625.8 ORY89308.1 - 0.1 12.8 0.0 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) DUF3173 PF11372.8 ORY89308.1 - 0.17 11.8 0.0 5.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Fcf1 PF04900.12 ORY89309.1 - 1.7e-37 127.7 0.4 3.2e-37 126.9 0.4 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 ORY89309.1 - 8.9e-13 48.6 0.2 1.3e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 PIN like domain 5_3_exonuc PF01367.20 ORY89309.1 - 0.047 14.3 0.1 0.085 13.5 0.1 1.4 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DoxX_3 PF13781.6 ORY89310.1 - 0.08 13.6 0.4 0.23 12.1 0.4 1.7 1 0 0 1 1 1 0 DoxX-like family MFS_1 PF07690.16 ORY89311.1 - 3.9e-43 147.7 48.7 1.8e-42 145.6 48.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89311.1 - 1.1e-07 31.1 12.8 1.1e-07 31.1 12.8 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY89311.1 - 4e-05 22.3 13.3 4e-05 22.3 13.3 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_5_1 PF06946.11 ORY89311.1 - 3.2 8.2 8.3 0.2 12.1 1.2 2.6 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 AAA_5 PF07728.14 ORY89313.1 - 3.7e-93 308.8 2.0 7.7e-18 64.8 0.0 10.9 8 2 2 10 10 10 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 ORY89313.1 - 1.6e-51 172.9 0.0 1.4e-19 70.2 0.0 4.9 4 0 0 4 4 3 3 Midasin AAA lid domain AAA_7 PF12775.7 ORY89313.1 - 3.8e-25 88.4 0.3 1e-05 25.1 0.0 6.8 6 1 0 6 6 6 5 P-loop containing dynein motor region AAA_lid_5 PF17865.1 ORY89313.1 - 1e-24 86.6 0.0 3.6e-24 84.9 0.0 2.0 1 0 0 1 1 1 1 Midasin AAA lid domain AAA PF00004.29 ORY89313.1 - 1.2e-22 80.7 0.0 9e-05 22.9 0.0 7.4 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 ORY89313.1 - 2.8e-22 79.0 0.0 2e-10 40.6 0.0 7.4 6 1 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 ORY89313.1 - 2.7e-19 69.3 0.2 0.0023 17.0 0.0 7.4 8 0 0 8 8 8 5 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 ORY89313.1 - 5.8e-15 56.1 51.0 4e-07 30.6 1.2 10.9 12 1 0 12 12 7 5 AAA ATPase domain Dynein_heavy PF03028.15 ORY89313.1 - 9.2e-15 54.8 0.0 0.023 14.8 0.0 7.3 7 0 0 7 7 7 3 Dynein heavy chain region D6 P-loop domain AAA_18 PF13238.6 ORY89313.1 - 2.1e-14 54.2 0.0 0.19 12.2 0.0 6.7 6 0 0 6 6 5 4 AAA domain AAA_33 PF13671.6 ORY89313.1 - 2.4e-13 50.5 0.1 0.35 11.0 0.0 6.0 5 0 0 5 5 5 3 AAA domain AAA_22 PF13401.6 ORY89313.1 - 5.3e-13 49.4 1.1 0.042 14.1 0.0 7.4 7 0 0 7 7 6 2 AAA domain Sigma54_activat PF00158.26 ORY89313.1 - 5.7e-12 45.7 1.0 0.26 11.0 0.0 5.8 6 0 0 6 6 5 4 Sigma-54 interaction domain AAA_30 PF13604.6 ORY89313.1 - 2.6e-11 43.6 5.8 0.0085 15.8 0.0 7.5 7 1 0 7 7 7 2 AAA domain TsaE PF02367.17 ORY89313.1 - 5.8e-11 42.5 7.1 0.43 10.6 0.1 6.0 6 0 0 6 6 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 ORY89313.1 - 1.1e-09 38.1 11.2 0.016 14.8 0.1 6.4 6 0 0 6 6 6 3 AAA domain Sigma54_activ_2 PF14532.6 ORY89313.1 - 2e-09 37.7 0.3 0.081 13.0 0.0 5.9 5 0 0 5 5 5 1 Sigma-54 interaction domain AAA_14 PF13173.6 ORY89313.1 - 2.8e-09 37.1 0.0 0.17 12.0 0.0 5.1 6 0 0 6 6 5 3 AAA domain IstB_IS21 PF01695.17 ORY89313.1 - 6.2e-09 35.8 0.1 0.34 10.6 0.0 4.9 4 0 0 4 4 4 2 IstB-like ATP binding protein T2SSE PF00437.20 ORY89313.1 - 4.5e-08 32.5 3.8 0.13 11.3 0.0 5.8 6 0 0 6 6 6 2 Type II/IV secretion system protein Zeta_toxin PF06414.12 ORY89313.1 - 5.1e-08 32.4 2.7 0.5 9.6 0.0 5.6 6 0 0 6 6 5 2 Zeta toxin AAA_19 PF13245.6 ORY89313.1 - 7.8e-08 32.8 2.3 7.6 6.9 0.0 6.0 6 0 0 6 6 6 0 AAA domain RNA_helicase PF00910.22 ORY89313.1 - 3.9e-07 30.4 0.8 4 7.9 0.0 5.5 5 0 0 5 5 5 0 RNA helicase AAA_28 PF13521.6 ORY89313.1 - 7.3e-07 29.6 9.4 0.41 10.9 0.0 6.0 6 0 0 6 6 6 2 AAA domain ABC_tran PF00005.27 ORY89313.1 - 8e-07 29.7 0.1 1 9.9 0.0 5.6 5 0 0 5 5 5 1 ABC transporter AAA_29 PF13555.6 ORY89313.1 - 2.5e-06 27.1 1.6 7 6.5 0.0 5.7 6 0 0 6 6 5 0 P-loop containing region of AAA domain NACHT PF05729.12 ORY89313.1 - 4.6e-06 26.7 6.1 0.89 9.5 0.0 5.7 5 0 0 5 5 5 1 NACHT domain RsgA_GTPase PF03193.16 ORY89313.1 - 3.6e-05 23.7 0.1 5.3 6.9 0.0 5.2 5 0 0 5 5 5 0 RsgA GTPase RuvB_N PF05496.12 ORY89313.1 - 3.7e-05 23.5 7.1 0.83 9.4 0.0 6.0 7 0 0 7 7 5 2 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 ORY89313.1 - 0.00026 20.3 4.3 0.64 9.1 0.1 4.5 5 0 0 5 5 5 1 Protein of unknown function (DUF815) DEAD PF00270.29 ORY89313.1 - 0.00036 20.4 0.3 1.8 8.3 0.0 3.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase SRP54 PF00448.22 ORY89313.1 - 0.00085 19.0 4.5 0.9 9.1 0.2 4.2 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain TniB PF05621.11 ORY89313.1 - 0.0024 17.3 0.0 26 4.1 0.0 4.8 6 0 0 6 6 4 0 Bacterial TniB protein PhoH PF02562.16 ORY89313.1 - 0.0024 17.4 0.1 12 5.3 0.0 3.7 3 0 0 3 3 3 0 PhoH-like protein IPT PF01745.16 ORY89313.1 - 0.0027 17.1 0.5 9.2 5.6 0.0 3.6 4 0 0 4 4 3 0 Isopentenyl transferase DAP3 PF10236.9 ORY89313.1 - 0.0037 16.5 0.6 3.9 6.6 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Roc PF08477.13 ORY89313.1 - 0.0043 17.3 1.9 25 5.1 0.0 5.1 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 ORY89313.1 - 0.0044 17.0 0.3 2.4 8.1 0.0 4.1 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 ORY89313.1 - 0.0047 16.9 0.0 3.6 7.4 0.0 4.4 6 0 0 6 6 4 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 ORY89313.1 - 0.0055 16.1 3.7 30 3.9 0.0 6.5 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 ORY89313.1 - 0.012 15.5 2.2 5.3 6.9 0.0 4.7 6 0 0 6 6 5 0 Rad17 P-loop domain PduV-EutP PF10662.9 ORY89313.1 - 0.023 14.4 3.4 0.76 9.5 0.0 4.2 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.13 ORY89313.1 - 0.034 13.3 2.5 24 4.0 0.0 4.1 5 0 0 5 5 4 0 TIP49 P-loop domain Cytidylate_kin PF02224.18 ORY89313.1 - 0.046 13.4 2.0 8.7 6.0 0.0 3.6 4 0 0 4 4 3 0 Cytidylate kinase dNK PF01712.19 ORY89313.1 - 0.048 13.5 0.7 3.4 7.5 0.0 3.4 4 0 0 4 4 4 0 Deoxynucleoside kinase CbiA PF01656.23 ORY89313.1 - 0.058 13.5 0.0 53 3.9 0.0 3.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DnaB_C PF03796.15 ORY89313.1 - 0.069 12.5 3.7 23 4.2 0.0 4.4 5 0 0 5 5 4 0 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 ORY89313.1 - 0.64 9.9 8.6 19 5.2 0.1 5.2 6 0 0 6 6 5 0 NTPase AAA_23 PF13476.6 ORY89313.1 - 0.97 9.9 0.0 0.97 9.9 0.0 6.8 7 1 0 7 7 6 0 AAA domain cobW PF02492.19 ORY89313.1 - 4.7 6.8 9.6 57 3.2 0.0 5.7 7 0 0 7 7 6 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 ORY89313.1 - 5.4 6.7 7.2 16 5.2 0.1 4.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein YqeY PF09424.10 ORY89314.1 - 3.1e-25 88.9 1.4 4.7e-25 88.3 1.4 1.2 1 0 0 1 1 1 1 Yqey-like protein PurS PF02700.14 ORY89314.1 - 0.028 14.6 2.2 0.054 13.7 2.2 1.5 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Myb_DNA-bind_6 PF13921.6 ORY89315.1 - 9.6e-42 141.1 15.6 3.5e-13 49.6 0.1 5.7 3 2 2 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY89315.1 - 1.2e-38 131.0 30.5 1e-10 41.6 0.6 5.8 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY89315.1 - 0.011 15.6 3.1 9.7 6.2 0.1 4.6 2 1 1 4 4 4 0 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 ORY89315.1 - 0.064 13.6 15.2 0.78 10.2 1.4 4.3 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain HTH_29 PF13551.6 ORY89315.1 - 0.1 12.6 4.3 0.097 12.7 0.8 3.0 2 0 0 2 2 2 0 Winged helix-turn helix Rap1_C PF11626.8 ORY89315.1 - 0.22 11.6 1.5 24 5.1 1.0 3.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF1664 PF07889.12 ORY89315.1 - 0.84 9.7 5.5 0.58 10.2 0.6 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) MADF_DNA_bdg PF10545.9 ORY89315.1 - 3.6 8.0 11.8 29 5.1 0.4 4.9 4 1 1 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 ORY89315.1 - 7.4 6.8 8.8 12 6.2 0.3 3.8 3 2 1 5 5 5 0 SANT/Myb-like domain of DAMP1 DNA_binding_1 PF01035.20 ORY89316.1 - 6.8e-23 80.6 3.7 1.8e-22 79.2 3.7 1.6 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Aa_trans PF01490.18 ORY89317.1 - 8.2e-34 117.0 26.5 9.8e-34 116.7 26.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.21 ORY89317.1 - 0.00043 19.0 17.9 0.00043 19.0 17.9 2.1 2 0 0 2 2 2 1 Amino acid permease MotA_ExbB PF01618.16 ORY89317.1 - 0.066 13.0 0.1 0.39 10.5 0.1 2.3 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Phage_holin_3_3 PF16083.5 ORY89317.1 - 0.15 12.2 0.0 0.15 12.2 0.0 4.3 3 2 1 4 4 4 0 LydA holin phage, holin superfamily III DUF3119 PF11317.8 ORY89317.1 - 0.18 12.1 0.4 0.93 9.8 0.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3119) Transgly_assoc PF04226.13 ORY89317.1 - 0.2 11.9 0.3 0.2 11.9 0.3 5.1 5 1 0 5 5 5 0 Transglycosylase associated protein DUF373 PF04123.13 ORY89317.1 - 1.4 8.2 9.8 0.42 10.0 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF373) PhyH PF05721.13 ORY89318.1 - 1.9e-23 83.8 0.1 2.9e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.18 ORY89319.1 - 4.9e-07 29.8 9.4 7.6e-07 29.1 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY89319.1 - 2.8e-05 23.3 0.5 2.8e-05 23.3 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldolase_II PF00596.21 ORY89320.1 - 7.2e-46 156.5 0.0 9.1e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain START PF01852.19 ORY89321.1 - 8e-11 41.7 0.0 2.7e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 START domain RAC_head PF16717.5 ORY89322.1 - 4.1e-22 79.0 2.8 4.1e-22 79.0 2.8 3.6 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 ORY89322.1 - 1.3e-17 63.6 0.2 4.3e-17 62.0 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain YjbH PF06082.11 ORY89322.1 - 0.88 8.3 6.1 1.3 7.7 6.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Presenilin PF01080.17 ORY89322.1 - 1.7 7.3 7.7 3.2 6.4 7.7 1.4 1 0 0 1 1 1 0 Presenilin Podoplanin PF05808.11 ORY89322.1 - 7.5 6.6 8.7 5.3 7.1 5.3 2.1 1 1 1 2 2 2 0 Podoplanin SET PF00856.28 ORY89323.1 - 3.8e-17 63.2 0.2 3.8e-17 63.2 0.2 3.8 3 2 0 3 3 3 1 SET domain RRM_1 PF00076.22 ORY89323.1 - 9.4e-09 35.0 0.0 1.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) N-SET PF11764.8 ORY89323.1 - 1e-08 35.5 0.2 1e-08 35.5 0.2 3.6 3 1 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 ORY89323.1 - 8e-05 22.2 0.0 0.00018 21.1 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 ORY89323.1 - 0.086 12.9 0.0 6.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GFO_IDH_MocA PF01408.22 ORY89324.1 - 2e-13 51.2 0.0 4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 ORY89324.1 - 1.4e-09 38.0 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Acyl-CoA_dh_1 PF00441.24 ORY89325.1 - 0.044 14.0 0.4 0.064 13.5 0.4 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain SNase PF00565.17 ORY89326.1 - 8.2e-52 174.2 0.4 1.1e-20 74.1 0.0 6.6 6 1 0 6 6 6 6 Staphylococcal nuclease homologue TUDOR PF00567.24 ORY89326.1 - 8.1e-20 71.1 0.0 1.8e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 ORY89326.1 - 0.058 13.9 0.2 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 Agenet domain adh_short PF00106.25 ORY89327.1 - 7.9e-34 116.8 0.0 1.2e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY89327.1 - 1.3e-27 96.9 0.0 1.7e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY89327.1 - 9.2e-10 38.7 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY89327.1 - 5.3e-06 26.5 0.1 1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 ORY89328.1 - 1.6e-36 125.6 0.0 2.2e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY89328.1 - 4.5e-24 85.3 0.0 6.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY89328.1 - 3.1e-11 43.5 0.1 5.4e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY89328.1 - 2.2e-05 24.4 0.1 4.1e-05 23.5 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY89328.1 - 0.013 14.7 0.1 0.025 13.7 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 ORY89328.1 - 0.018 14.5 0.1 0.05 13.1 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY89328.1 - 0.11 12.1 0.1 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family F-box-like PF12937.7 ORY89329.1 - 6.1e-06 26.0 0.6 2.2e-05 24.2 0.6 2.0 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.26 ORY89330.1 - 0.00069 19.9 0.1 0.0012 19.2 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY89330.1 - 0.0008 19.4 0.2 0.001 19.0 0.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY89330.1 - 0.0068 17.1 0.2 0.011 16.5 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger HalOD2 PF18547.1 ORY89330.1 - 0.099 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Halobacterial output domain 2 TPT PF03151.16 ORY89332.1 - 2.2e-23 83.0 18.4 3.2e-23 82.5 18.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY89332.1 - 0.3 11.3 29.4 0.1 12.8 5.8 2.3 2 0 0 2 2 2 0 EamA-like transporter family TPT PF03151.16 ORY89333.1 - 5.2e-16 58.8 15.0 1.7e-15 57.1 15.0 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family CLASP_N PF12348.8 ORY89334.1 - 2e-66 223.8 0.0 1.4e-59 201.5 0.0 4.2 4 0 0 4 4 4 3 CLASP N terminal HEAT PF02985.22 ORY89334.1 - 4.7e-05 23.3 3.0 3.2 8.3 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat CSTF2_hinge PF14327.6 ORY89334.1 - 0.024 15.1 3.9 2.5 8.6 0.5 3.0 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 HEAT_EZ PF13513.6 ORY89334.1 - 0.037 14.5 2.7 11 6.6 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat Cnd1 PF12717.7 ORY89334.1 - 0.074 13.1 0.0 12 5.9 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Aminotran_3 PF00202.21 ORY89335.1 - 2.2e-99 332.9 0.0 2.8e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY89335.1 - 0.00014 21.2 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Glyco_transf_90 PF05686.12 ORY89336.1 - 1.7e-18 66.7 0.3 8.6e-17 61.1 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 90 Rabaptin PF03528.15 ORY89336.1 - 0.2 10.4 0.1 0.27 9.9 0.1 1.1 1 0 0 1 1 1 0 Rabaptin Porin_3 PF01459.22 ORY89337.1 - 3.7e-69 233.2 0.1 4.4e-69 233.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Ribosomal_S21e PF01249.18 ORY89338.1 - 6.1e-40 135.2 0.1 7.9e-40 134.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e GFA PF04828.14 ORY89338.1 - 0.061 13.7 0.9 1.2 9.5 0.9 2.1 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme WD40 PF00400.32 ORY89339.1 - 3e-06 27.8 17.9 1.2 10.1 0.0 7.0 7 1 0 7 7 7 4 WD domain, G-beta repeat SKG6 PF08693.10 ORY89340.1 - 0.0026 17.1 2.8 0.0048 16.3 2.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain zf-MYND PF01753.18 ORY89341.1 - 1.5e-10 41.0 13.7 2.2e-10 40.4 13.7 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 ORY89341.1 - 0.019 14.9 7.1 0.028 14.3 7.1 1.3 1 0 0 1 1 1 0 HIT zinc finger zinc_ribbon_5 PF13719.6 ORY89341.1 - 0.062 13.1 3.4 0.13 12.1 3.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-C6H2 PF15801.5 ORY89341.1 - 0.61 10.4 10.6 1.1 9.7 10.6 1.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Ecl1 PF12855.7 ORY89341.1 - 1.3 10.2 4.7 0.38 11.9 0.4 2.0 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins C1_2 PF03107.16 ORY89341.1 - 1.4 9.2 5.7 2.7 8.4 5.7 1.4 1 0 0 1 1 1 0 C1 domain PolC_DP2 PF03833.13 ORY89341.1 - 2.9 5.6 6.0 4.3 5.1 5.9 1.3 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 Mannosyl_trans3 PF11051.8 ORY89342.1 - 1.2e-28 100.3 0.0 8.1e-20 71.3 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_90 PF05686.12 ORY89343.1 - 1.1e-13 50.9 0.8 2.6e-09 36.5 1.7 3.6 3 1 0 3 3 3 2 Glycosyl transferase family 90 PC4 PF02229.16 ORY89344.1 - 6.5e-23 80.1 1.4 7.5e-23 79.9 0.3 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) HTH_OrfB_IS605 PF12323.8 ORY89344.1 - 0.096 12.2 0.7 4.6 6.8 0.1 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain F-protein PF00469.20 ORY89344.1 - 0.17 11.5 3.5 0.21 11.1 3.5 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef FAM176 PF14851.6 ORY89344.1 - 2.1 8.0 7.3 2.4 7.8 6.8 1.4 1 1 0 1 1 1 0 FAM176 family SURF2 PF05477.11 ORY89344.1 - 9.1 5.9 13.7 5.7 6.6 11.7 1.6 1 1 1 2 2 2 0 Surfeit locus protein 2 (SURF2) F-box-like PF12937.7 ORY89345.1 - 4.2e-07 29.7 0.6 1.4e-06 28.1 0.6 2.0 1 0 0 1 1 1 1 F-box-like AMPKBI PF04739.15 ORY89345.1 - 0.074 13.3 0.0 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain DnaJ_C PF01556.18 ORY89346.1 - 6.5e-44 149.6 0.4 8.4e-44 149.2 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY89346.1 - 2.4e-23 82.0 0.6 4.5e-23 81.1 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY89346.1 - 1.6e-15 57.2 20.0 2.6e-15 56.5 20.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY89346.1 - 0.013 15.5 8.4 0.3 11.1 0.5 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORY89346.1 - 0.5 10.4 10.3 2.1 8.4 2.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA A2L_zn_ribbon PF08792.10 ORY89346.1 - 4.4 7.1 18.8 1.1 9.1 0.3 4.2 3 1 1 4 4 4 0 A2L zinc ribbon domain DZR PF12773.7 ORY89346.1 - 5.8 7.0 10.5 28 4.9 6.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon Adaptin_N PF01602.20 ORY89347.1 - 6.6e-129 430.8 10.1 8.1e-129 430.5 10.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY89347.1 - 4.2e-61 205.7 3.1 9.3e-61 204.6 0.7 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY89347.1 - 8e-14 51.8 3.8 1.2e-07 32.0 0.6 4.9 3 1 3 6 6 6 4 HEAT repeats HEAT PF02985.22 ORY89347.1 - 2.6e-07 30.3 2.9 0.049 13.9 0.0 4.9 6 0 0 6 6 5 2 HEAT repeat HEAT_EZ PF13513.6 ORY89347.1 - 0.00021 21.7 2.2 2.1 9.0 0.1 4.9 4 1 1 5 5 4 2 HEAT-like repeat Arm PF00514.23 ORY89347.1 - 0.001 19.1 2.4 0.6 10.2 0.0 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF1548 PF07579.11 ORY89347.1 - 0.0026 18.1 0.1 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1548) Cnd3 PF12719.7 ORY89347.1 - 0.0028 16.9 0.2 0.84 8.8 0.0 2.3 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 ORY89347.1 - 0.022 14.3 3.2 2.4 7.7 0.0 4.0 3 1 0 4 4 4 0 CLASP N terminal TFCD_C PF12612.8 ORY89347.1 - 0.071 12.9 0.2 0.17 11.7 0.2 1.6 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal UME PF08064.13 ORY89347.1 - 0.38 10.7 4.0 1.3 9.0 0.1 3.6 5 0 0 5 5 5 0 UME (NUC010) domain Sec7 PF01369.20 ORY89348.1 - 1.2e-29 103.3 0.0 3.1e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 ORY89348.1 - 3.7e-25 88.6 0.0 6.9e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY89348.1 - 6.5e-05 23.4 0.0 0.00015 22.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PCI PF01399.27 ORY89349.1 - 4.1e-07 30.5 0.0 1.2e-06 29.0 0.0 1.8 1 1 0 1 1 1 1 PCI domain TPR_2 PF07719.17 ORY89349.1 - 0.012 15.7 1.1 0.065 13.4 1.1 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY89349.1 - 0.043 14.5 0.6 1.2 9.8 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_4 PF01565.23 ORY89350.1 - 5e-25 87.8 0.3 2.5e-23 82.4 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain FAD-oxidase_C PF02913.19 ORY89350.1 - 4.9e-12 46.0 0.0 7.2e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain zf-C2H2 PF00096.26 ORY89351.1 - 0.00071 19.9 0.1 0.0012 19.2 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY89351.1 - 0.0008 19.3 0.2 0.001 19.0 0.2 1.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY89351.1 - 0.0069 17.1 0.2 0.011 16.5 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger Evr1_Alr PF04777.13 ORY89351.1 - 0.17 12.4 0.0 0.18 12.3 0.0 1.1 1 0 0 1 1 1 0 Erv1 / Alr family F-box PF00646.33 ORY89352.1 - 0.00032 20.5 0.1 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 F-box domain DUF5630 PF18632.1 ORY89352.1 - 0.032 13.6 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5630) F-box_4 PF15966.5 ORY89352.1 - 0.12 12.2 0.4 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 F-box EST1_DNA_bind PF10373.9 ORY89353.1 - 9.8e-36 123.7 0.2 1.9e-33 116.1 0.2 2.3 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 ORY89353.1 - 8.7e-16 58.8 0.0 4.1e-15 56.6 0.0 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 zf-rbx1 PF12678.7 ORY89354.1 - 2.6e-12 46.8 2.6 5.5e-12 45.8 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY89354.1 - 4.2e-10 39.8 7.6 6.6e-10 39.2 4.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY89354.1 - 2.7e-07 30.3 1.4 6.5e-07 29.1 1.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY89354.1 - 9.5e-07 28.6 5.3 2.1e-06 27.4 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY89354.1 - 2.7e-06 27.3 4.7 5.6e-06 26.3 4.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY89354.1 - 1.4e-05 24.9 4.3 0.00021 21.1 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY89354.1 - 0.0001 22.0 3.8 0.00018 21.2 0.9 2.3 2 0 0 2 2 2 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 ORY89354.1 - 0.0013 18.3 2.7 0.0029 17.2 2.7 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 ORY89354.1 - 0.0019 18.2 6.4 0.0093 16.0 6.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY89354.1 - 0.0029 17.5 6.4 0.014 15.3 6.6 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY89354.1 - 0.0048 17.0 1.6 0.0098 16.0 1.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY89354.1 - 0.0096 15.8 6.0 0.022 14.6 6.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 ORY89354.1 - 0.5 10.7 4.0 0.86 10.0 4.0 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 ORY89354.1 - 0.82 9.9 3.3 2.4 8.4 3.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 ORY89354.1 - 3.6 7.5 5.4 1.1 9.1 2.1 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Solute_trans_a PF03619.16 ORY89355.1 - 8.5e-86 287.7 14.7 1e-85 287.5 14.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DNMT1-RFD PF12047.8 ORY89355.1 - 0.23 11.5 0.0 0.43 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain Beta_helix PF13229.6 ORY89356.1 - 2.8e-07 30.5 17.0 1.2e-05 25.2 13.3 3.5 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 ORY89356.1 - 6.1e-05 22.4 6.5 0.00032 20.0 1.9 2.6 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pol_alpha_B_N PF08418.10 ORY89356.1 - 0.15 12.0 5.5 0.25 11.3 5.5 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Apt1 PF10351.9 ORY89356.1 - 1.3 7.8 4.4 1.6 7.5 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAP1 PF08601.10 ORY89356.1 - 5.3 6.7 16.8 9.7 5.8 16.8 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.9 ORY89356.1 - 5.5 5.4 7.0 7.4 5.0 7.0 1.1 1 0 0 1 1 1 0 Macoilin family NiFe_hyd_3_EhaA PF17367.2 ORY89357.1 - 0.068 13.3 0.6 0.15 12.2 0.4 1.7 1 1 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A PAP1 PF08601.10 ORY89357.1 - 4.6 6.9 10.4 5.1 6.7 10.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Pkinase PF00069.25 ORY89358.1 - 8.5e-57 192.5 0.0 1.3e-56 191.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sfi1 PF08457.10 ORY89358.1 - 3.7e-24 85.2 102.5 9.4e-10 37.6 29.0 4.1 1 1 2 3 3 3 3 Sfi1 spindle body protein Pkinase_Tyr PF07714.17 ORY89358.1 - 3e-21 75.9 0.0 5.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY89358.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 ORY89358.1 - 0.0037 16.9 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF5357 PF17310.2 ORY89358.1 - 0.074 11.6 0.7 0.12 10.9 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Serglycin PF04360.12 ORY89358.1 - 0.16 11.9 1.4 0.32 11.0 1.4 1.4 1 0 0 1 1 1 0 Serglycin UvrD-helicase PF00580.21 ORY89358.1 - 0.83 9.1 2.3 3.4 7.1 0.1 2.4 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Pkinase PF00069.25 ORY89359.1 - 5.6e-64 216.1 0.0 7.6e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89359.1 - 8.2e-25 87.6 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY89359.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY89359.1 - 0.027 14.4 0.0 0.11 12.4 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY89359.1 - 0.038 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 ORY89359.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY89359.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lactamase_B_2 PF12706.7 ORY89360.1 - 7e-23 81.2 0.0 1.2e-22 80.4 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY89360.1 - 0.00084 19.3 0.0 0.0018 18.2 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CorA PF01544.18 ORY89362.1 - 1.5e-06 27.7 0.1 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SfLAP PF11139.8 ORY89362.1 - 0.067 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF1980 PF09323.10 ORY89362.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RNA_pol_Rpc4 PF05132.14 ORY89362.1 - 8.3 6.8 10.9 14 6.1 10.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 F-box-like PF12937.7 ORY89363.1 - 2.3e-07 30.6 1.0 5.8e-07 29.3 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY89363.1 - 0.046 13.6 0.2 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 F-box domain ATG16 PF08614.11 ORY89364.1 - 0.0011 19.2 2.4 0.0011 19.2 2.4 5.0 4 1 0 4 4 4 1 Autophagy protein 16 (ATG16) BST2 PF16716.5 ORY89364.1 - 0.0014 19.2 0.8 0.0058 17.2 0.3 2.4 2 0 0 2 2 2 1 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 ORY89364.1 - 0.0023 18.0 9.9 0.0023 18.0 9.9 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 ORY89364.1 - 0.012 15.0 0.2 0.029 13.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) FAM76 PF16046.5 ORY89364.1 - 0.015 14.7 0.0 0.015 14.7 0.0 3.3 2 2 1 3 3 3 0 FAM76 protein TMF_TATA_bd PF12325.8 ORY89364.1 - 0.046 14.0 9.4 0.094 12.9 8.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 ORY89364.1 - 0.057 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GAS PF13851.6 ORY89364.1 - 0.2 11.0 3.9 0.62 9.4 2.9 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3810 PF12725.7 ORY89365.1 - 0.69 9.2 4.4 0.9 8.8 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Glyco_transf_90 PF05686.12 ORY89366.1 - 5.4e-12 45.3 0.2 1.8e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Pyr_redox_3 PF13738.6 ORY89367.1 - 0.00035 19.9 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY89367.1 - 0.00058 20.0 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY89367.1 - 0.00094 18.5 0.1 0.0031 16.8 0.0 1.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY89367.1 - 0.0012 18.2 0.1 0.0073 15.6 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 ORY89367.1 - 0.0028 17.6 1.4 0.0059 16.6 0.0 2.3 3 0 0 3 3 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY89367.1 - 0.0043 16.3 0.1 0.0077 15.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY89367.1 - 0.013 14.8 0.1 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 ORY89367.1 - 0.03 14.6 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 ORY89367.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY89367.1 - 0.071 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ORY89367.1 - 0.08 12.0 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 ORY89367.1 - 0.12 11.0 0.3 0.17 10.5 0.3 1.1 1 0 0 1 1 1 0 HI0933-like protein VbhA PF18495.1 ORY89367.1 - 0.13 12.2 0.4 0.36 10.7 0.4 1.7 1 0 0 1 1 1 0 Antitoxin VbhA Glyco_transf_90 PF05686.12 ORY89368.1 - 2.8e-22 79.2 0.2 1.8e-14 53.5 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 GTP_cyclohydroI PF01227.22 ORY89369.1 - 6.6e-73 243.9 0.0 8.6e-73 243.6 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ORY89369.1 - 0.0038 17.3 0.0 0.0071 16.5 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein HATPase_c_2 PF13581.6 ORY89369.1 - 0.062 13.3 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain CALM_bind PF16025.5 ORY89369.1 - 0.25 11.8 2.3 1.4 9.5 0.7 2.5 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding Rhomboid PF01694.22 ORY89370.1 - 2.2e-27 95.9 11.5 3.8e-27 95.1 11.5 1.3 1 0 0 1 1 1 1 Rhomboid family F-box-like PF12937.7 ORY89372.1 - 3.8e-07 29.9 0.9 9.8e-07 28.6 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY89372.1 - 0.049 13.5 0.2 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 F-box domain PTR2 PF00854.21 ORY89374.1 - 4.9e-60 203.4 10.4 6.9e-60 202.9 10.4 1.1 1 0 0 1 1 1 1 POT family DUF3149 PF11346.8 ORY89374.1 - 0.058 13.0 0.2 0.19 11.4 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) CLPTM1 PF05602.12 ORY89375.1 - 1.9e-134 448.9 0.2 2.5e-134 448.5 0.2 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 ORY89375.1 - 8.3e-05 22.3 2.5 0.00011 21.9 1.1 2.0 2 0 0 2 2 2 1 PQ loop repeat adh_short PF00106.25 ORY89376.1 - 1.5e-16 60.4 0.1 2.5e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY89376.1 - 1.1e-10 41.5 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY89376.1 - 0.00017 21.6 0.1 0.0004 20.4 0.1 1.6 2 0 0 2 2 2 1 KR domain GHMP_kinases_C PF08544.13 ORY89376.1 - 0.064 13.6 0.2 0.18 12.2 0.2 1.8 1 0 0 1 1 1 0 GHMP kinases C terminal TAL_FSA PF00923.19 ORY89377.1 - 4.1e-94 315.1 0.0 4.7e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SNF2_N PF00176.23 ORY89378.1 - 3.6e-67 226.6 0.1 5.7e-67 225.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY89378.1 - 3.8e-15 56.2 0.0 1.2e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 ORY89378.1 - 1.7e-08 34.3 0.0 3.9e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4 PF00097.25 ORY89378.1 - 3.2e-06 26.9 15.2 6.4e-06 25.9 15.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY89378.1 - 3.4e-05 23.6 12.0 5.8e-05 22.9 12.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY89378.1 - 5e-05 23.5 14.7 0.00012 22.3 14.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY89378.1 - 0.0001 22.0 13.3 0.0001 22.0 13.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY89378.1 - 0.00093 19.1 14.9 0.0033 17.3 15.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY89378.1 - 0.0021 18.0 11.8 0.0054 16.7 11.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 ORY89378.1 - 0.0024 17.9 0.0 0.0066 16.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 ORY89378.1 - 0.0026 17.6 11.6 0.0055 16.5 11.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY89378.1 - 0.031 14.5 13.2 0.072 13.3 13.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY89378.1 - 0.15 12.0 5.1 0.31 10.9 5.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein WW PF00397.26 ORY89378.1 - 0.19 11.8 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 WW domain zf-RING_10 PF16685.5 ORY89378.1 - 1.4 9.1 8.6 3 8.1 8.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORY89378.1 - 3.6 7.9 16.1 0.82 10.0 11.6 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger domain YwiC PF14256.6 ORY89379.1 - 0.11 12.8 2.5 0.23 11.8 2.5 1.5 1 0 0 1 1 1 0 YwiC-like protein PEX11 PF05648.14 ORY89380.1 - 2.5e-06 27.1 2.9 0.019 14.5 0.1 2.6 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) IFT20 PF14931.6 ORY89380.1 - 0.075 13.2 1.0 0.13 12.5 1.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 RasGAP PF00616.19 ORY89382.1 - 1.6e-33 116.2 0.0 4.3e-31 108.2 0.0 2.3 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 ORY89382.1 - 1.1e-11 44.9 0.0 2.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain NAD_kinase PF01513.21 ORY89383.1 - 1.2e-72 244.6 0.0 4e-72 242.9 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase COPI_C PF06957.11 ORY89383.1 - 0.22 10.2 5.8 0.37 9.5 5.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.12 ORY89383.1 - 0.3 9.3 9.4 0.54 8.4 9.4 1.3 1 0 0 1 1 1 0 Nop14-like family Y_phosphatase2 PF03162.13 ORY89384.1 - 9.8e-50 168.4 0.0 1.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY89384.1 - 0.0019 18.2 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY89384.1 - 0.033 13.7 0.0 0.044 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TPR_MLP1_2 PF07926.12 ORY89388.1 - 0.00099 19.2 5.8 0.00099 19.2 5.8 5.9 3 2 2 5 5 5 2 TPR/MLP1/MLP2-like protein FlgT_C PF16538.5 ORY89388.1 - 0.048 14.2 0.2 16 6.1 0.0 3.0 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain BRI3BP PF14965.6 ORY89388.1 - 0.1 12.1 0.2 4.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Negative regulator of p53/TP53 Spc7 PF08317.11 ORY89388.1 - 0.59 9.0 52.5 0.72 8.7 10.4 4.2 1 1 3 4 4 4 0 Spc7 kinetochore protein ORF6C PF10552.9 ORY89388.1 - 1.2 9.2 12.0 0.11 12.6 0.8 3.4 3 1 0 3 3 3 0 ORF6C domain ATG16 PF08614.11 ORY89388.1 - 1.9 8.7 62.3 0.34 11.1 5.7 5.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 ORY89388.1 - 2.5 8.4 22.9 1.1 9.5 1.5 5.1 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 ORY89388.1 - 3.3 8.1 60.7 1 9.8 10.9 4.6 2 1 3 5 5 5 0 Fez1 NPV_P10 PF05531.12 ORY89388.1 - 3.4 8.2 6.6 75 3.9 0.1 4.5 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 ORY89388.1 - 7.8 6.3 29.4 0.072 12.9 6.8 4.4 3 1 1 4 4 4 0 Phage minor structural protein GP20 EloA-BP1 PF15870.5 ORY89389.1 - 0.00013 22.3 0.1 0.0002 21.6 0.1 1.3 1 0 0 1 1 1 1 ElonginA binding-protein 1 RNase_T PF00929.24 ORY89389.1 - 0.0038 17.8 0.0 0.0099 16.4 0.0 1.7 1 0 0 1 1 1 1 Exonuclease Granulin PF00396.18 ORY89389.1 - 0.054 13.8 0.5 0.054 13.8 0.5 1.9 2 0 0 2 2 2 0 Granulin CHORD PF04968.12 ORY89389.1 - 0.084 13.6 4.3 0.16 12.7 4.3 1.5 1 0 0 1 1 1 0 CHORD DcpS_C PF11969.8 ORY89390.1 - 6.1e-14 52.5 2.4 9.2e-14 51.9 1.1 2.0 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORY89390.1 - 1.9e-10 41.4 1.9 4.2e-10 40.2 0.2 2.2 2 1 0 2 2 2 1 HIT domain zf-C2HE PF16278.5 ORY89390.1 - 5.1e-07 30.0 1.0 5.1e-07 30.0 1.0 2.1 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DUF2340 PF10209.9 ORY89391.1 - 9.8e-51 171.2 0.2 1.1e-50 171.0 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Ubiquitin_4 PF18036.1 ORY89391.1 - 0.019 15.0 0.0 0.29 11.2 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain Beta_helix PF13229.6 ORY89393.1 - 2.5e-07 30.7 19.8 3.7e-05 23.6 3.5 2.9 1 1 2 3 3 3 2 Right handed beta helix region NosD PF05048.13 ORY89393.1 - 9.8e-06 25.0 0.5 9.8e-06 25.0 0.5 2.6 2 2 1 3 3 3 1 Periplasmic copper-binding protein (NosD) PAP1 PF08601.10 ORY89393.1 - 0.89 9.2 18.5 1.4 8.6 18.5 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 ORY89393.1 - 4.2 6.1 5.8 5.5 5.7 5.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 ORY89393.1 - 7.8 6.3 7.0 10 5.9 7.0 1.1 1 0 0 1 1 1 0 SPX domain adh_short PF00106.25 ORY89394.1 - 1.1e-34 119.6 0.0 1.5e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY89394.1 - 3.2e-25 89.1 0.0 4.5e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY89394.1 - 4.6e-08 33.2 0.0 7.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY89394.1 - 0.00019 21.4 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY89394.1 - 0.0014 17.8 0.0 0.0033 16.6 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain Epimerase PF01370.21 ORY89394.1 - 0.0016 18.0 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY89394.1 - 0.0065 15.6 0.0 0.011 14.9 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Apt1 PF10351.9 ORY89395.1 - 1.6 7.5 5.0 2.2 7.0 5.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_L29 PF00831.23 ORY89396.1 - 6.3e-18 64.5 2.9 6.3e-18 64.5 2.9 2.3 2 0 0 2 2 2 1 Ribosomal L29 protein DUF737 PF05300.11 ORY89396.1 - 0.067 13.5 5.7 0.76 10.1 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF737) HSF_DNA-bind PF00447.17 ORY89398.1 - 2.9e-17 63.1 0.0 4.1e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Lipase_GDSL PF00657.22 ORY89399.1 - 5e-08 33.2 0.0 5.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY89399.1 - 0.018 15.4 5.3 0.13 12.6 5.2 2.1 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 ORY89400.1 - 6.2e-13 49.0 13.0 5.7e-05 23.8 0.7 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89400.1 - 5.8e-08 32.9 0.2 0.014 15.7 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY89400.1 - 0.00074 18.1 0.1 0.052 12.1 0.0 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain FAA_hydro_N_2 PF18288.1 ORY89400.1 - 0.0059 17.0 0.4 3.6 8.1 0.1 2.5 2 0 0 2 2 2 2 Fumarylacetoacetase N-terminal domain 2 PQQ_2 PF13360.6 ORY89400.1 - 0.037 13.6 0.5 0.26 10.8 0.2 2.3 2 1 0 2 2 2 0 PQQ-like domain WD40_like PF17005.5 ORY89400.1 - 0.15 11.4 0.0 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Coatomer_WDAD PF04053.14 ORY89400.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Spo7 PF03907.13 ORY89401.1 - 3.2e-28 98.7 0.1 5.2e-28 98.0 0.1 1.3 1 0 0 1 1 1 1 Spo7-like protein TRP PF06011.12 ORY89401.1 - 0.0022 16.8 2.3 0.0031 16.3 2.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel ATP-synt_A PF00119.20 ORY89401.1 - 0.0051 16.8 0.7 0.0072 16.3 0.7 1.1 1 0 0 1 1 1 1 ATP synthase A chain DUF485 PF04341.12 ORY89401.1 - 0.018 15.0 2.0 0.035 14.0 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF2663 PF10864.8 ORY89401.1 - 0.13 12.7 0.6 0.2 12.0 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) Tmemb_18A PF09771.9 ORY89401.1 - 0.14 12.5 0.1 0.21 12.0 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 188 DUF2207 PF09972.9 ORY89401.1 - 0.29 9.9 0.5 0.4 9.4 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec10 PF07393.11 ORY89402.1 - 3.8e-134 448.8 0.0 5.5e-134 448.2 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 ORY89402.1 - 2.7e-07 30.3 0.0 6.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY89402.1 - 0.0027 17.6 0.2 0.0075 16.1 0.2 1.8 1 0 0 1 1 1 1 F-box-like DUF5102 PF17104.5 ORY89402.1 - 1.5 8.8 7.5 0.13 12.3 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Lipase_GDSL_2 PF13472.6 ORY89403.1 - 1e-05 26.0 0.0 3e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY89403.1 - 0.034 14.1 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF953 PF06110.11 ORY89403.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AA_permease PF00324.21 ORY89404.1 - 6.6e-111 371.2 45.0 8e-111 371.0 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY89404.1 - 2.3e-43 148.6 48.9 2.8e-43 148.3 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease DNA_pol_A_exo1 PF01612.20 ORY89405.1 - 7.1e-16 58.4 0.0 1.3e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease N2227 PF07942.12 ORY89407.1 - 7.2e-87 291.0 0.0 9.6e-87 290.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Dscam_C PF12355.8 ORY89407.1 - 0.033 15.1 2.2 0.062 14.3 2.2 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal RCDG1 PF15725.5 ORY89407.1 - 1.5 9.3 6.0 3.5 8.1 6.0 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein IFRD PF05004.13 ORY89407.1 - 3.6 6.6 8.0 1.5 7.8 0.1 2.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) ETF_QO PF05187.13 ORY89408.1 - 9.9e-43 144.5 0.1 1.8e-42 143.7 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 ORY89408.1 - 1.4e-08 34.3 0.2 0.00017 20.8 0.7 2.2 1 1 1 2 2 2 2 FAD binding domain Thi4 PF01946.17 ORY89408.1 - 4.4e-07 29.4 0.0 0.00095 18.5 0.2 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 ORY89408.1 - 8.7e-07 29.1 0.1 8.7e-07 29.1 0.1 2.4 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY89408.1 - 3e-06 26.7 0.0 7.3e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY89408.1 - 5.1e-06 26.3 0.8 5e-05 23.0 0.6 2.5 2 1 1 3 3 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY89408.1 - 0.00011 21.5 0.1 0.00029 20.2 0.2 1.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY89408.1 - 0.00011 21.0 0.7 0.00017 20.4 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 ORY89408.1 - 0.00012 22.1 0.3 0.00026 21.0 0.3 1.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY89408.1 - 0.00042 19.5 0.2 0.00061 19.0 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY89408.1 - 0.00058 20.4 1.5 0.98 10.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY89408.1 - 0.0014 18.0 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY89408.1 - 0.0017 17.7 0.5 0.0027 17.0 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY89408.1 - 0.02 13.8 0.3 0.034 13.0 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Fer4_7 PF12838.7 ORY89408.1 - 0.025 15.1 0.7 0.057 14.0 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.6 ORY89408.1 - 0.23 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_2 PF12797.7 ORY89408.1 - 0.82 9.9 3.2 0.26 11.4 0.4 1.8 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_6 PF12837.7 ORY89408.1 - 1.7 8.9 4.1 0.78 9.9 0.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain SKN1 PF03935.15 ORY89409.1 - 5.9e-172 572.6 7.5 7.1e-172 572.3 7.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CcmD PF04995.14 ORY89410.1 - 0.11 12.7 2.1 0.21 11.7 2.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Dicty_REP PF05086.12 ORY89410.1 - 3.2 5.6 11.6 4.7 5.1 11.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein O-FucT PF10250.9 ORY89412.1 - 5e-11 42.9 0.0 8.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_90 PF05686.12 ORY89413.1 - 1.2e-16 60.6 2.1 8.9e-16 57.8 0.8 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 90 ECH_1 PF00378.20 ORY89414.1 - 5.3e-25 88.2 0.0 6.9e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY89414.1 - 3.1e-16 59.8 0.0 3.5e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NAPRTase PF04095.16 ORY89415.1 - 6.7e-55 186.3 0.0 2.1e-54 184.7 0.0 1.7 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 ORY89415.1 - 8.2e-26 90.8 0.1 1.3e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Fungal_trans PF04082.18 ORY89416.1 - 7.9e-35 120.2 1.0 1.1e-34 119.7 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-UBP PF02148.19 ORY89416.1 - 0.019 15.3 1.3 0.059 13.7 1.3 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2 PF00096.26 ORY89417.1 - 1.3e-05 25.4 1.1 3.3e-05 24.1 1.1 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY89417.1 - 0.015 16.1 0.9 0.015 16.1 0.9 2.1 3 0 0 3 3 3 0 C2H2-type zinc finger Forkhead PF00250.18 ORY89418.1 - 2.3e-32 111.1 0.0 2.6e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Forkhead domain TFIIS_M PF07500.14 ORY89420.1 - 5e-20 72.1 0.0 1.1e-19 70.9 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 ORY89420.1 - 5.1e-08 32.7 9.1 8.6e-08 32.0 9.1 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 ORY89420.1 - 6.7e-08 32.6 0.0 1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 SPOC domain PHD_2 PF13831.6 ORY89420.1 - 0.99 9.0 4.3 1.7 8.2 4.3 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 ORY89420.1 - 5.9 7.3 7.7 18 5.8 7.8 1.7 1 1 0 1 1 1 0 Ring finger domain WD40 PF00400.32 ORY89421.1 - 7e-42 140.6 12.7 4.3e-07 30.5 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89421.1 - 5e-15 55.6 1.1 0.00068 19.9 0.0 5.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY89421.1 - 6.4e-05 22.9 0.1 0.00063 19.7 0.0 2.4 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY89421.1 - 0.0069 15.1 9.9 0.071 11.7 0.4 3.5 2 2 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY89421.1 - 0.11 11.8 0.1 3.4 6.9 0.0 3.0 3 1 0 4 4 4 0 WD40-like domain Apolipoprotein PF01442.18 ORY89422.1 - 1.5e-06 28.2 15.9 2.6e-06 27.4 15.9 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 ORY89422.1 - 0.0067 17.0 20.8 0.12 13.0 10.2 2.9 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF883) Synuclein PF01387.17 ORY89422.1 - 0.035 14.3 7.7 0.035 14.3 7.7 2.1 1 1 1 2 2 2 0 Synuclein YtxH PF12732.7 ORY89422.1 - 0.2 12.2 26.2 1.8e+04 -6.5 26.2 3.1 1 1 0 1 1 1 0 YtxH-like protein ArAE_2_N PF10337.9 ORY89422.1 - 0.79 8.7 2.6 0.92 8.5 2.6 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF2884 PF11101.8 ORY89422.1 - 1 8.8 9.6 1 8.8 8.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) GREB1 PF15782.5 ORY89422.1 - 1.2 6.2 7.5 1.4 6.0 7.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ZT_dimer PF16916.5 ORY89422.1 - 2.6 8.2 7.2 5.4 7.2 0.5 2.9 2 1 0 3 3 3 0 Dimerisation domain of Zinc Transporter FUSC PF04632.12 ORY89422.1 - 3.2 6.2 8.4 4 5.8 8.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MBOAT_2 PF13813.6 ORY89423.1 - 2.3e-09 37.4 1.6 5.9e-09 36.1 1.6 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Ras PF00071.22 ORY89425.1 - 2.9e-48 163.6 0.0 3.9e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY89425.1 - 1.2e-29 103.0 0.0 2.4e-29 102.0 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY89425.1 - 1.6e-09 37.4 0.0 5.4e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY89425.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY89425.1 - 0.00035 20.1 0.0 0.0012 18.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY89425.1 - 0.0012 18.8 0.0 0.088 12.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY89425.1 - 0.0012 19.3 0.0 0.0043 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.9 ORY89425.1 - 0.0077 15.4 0.0 0.41 9.8 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 MMR_HSR1 PF01926.23 ORY89425.1 - 0.0083 16.2 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 ORY89425.1 - 0.027 14.5 0.0 0.042 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY89425.1 - 0.033 14.5 0.0 0.082 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY89425.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATP_bind_1 PF03029.17 ORY89425.1 - 0.051 13.4 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ORY89425.1 - 0.062 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY89425.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 ORY89425.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 ORY89425.1 - 0.17 11.6 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 ORY89426.1 - 0.0095 15.8 0.4 0.022 14.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like OTU PF02338.19 ORY89427.1 - 1.1e-20 74.4 0.0 3.5e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY89427.1 - 0.013 15.0 0.0 4.7 6.6 0.0 2.4 1 1 0 2 2 2 0 Peptidase C65 Otubain Lipase_GDSL_2 PF13472.6 ORY89428.1 - 0.013 15.9 0.4 0.021 15.3 0.4 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY89429.1 - 4.2e-05 23.6 0.0 5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY89429.1 - 0.11 12.8 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family HSF_DNA-bind PF00447.17 ORY89430.1 - 3.5e-17 62.8 0.0 5.1e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4211 PF13926.6 ORY89431.1 - 2.5e-22 79.5 0.0 8.8e-22 77.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) AF-4 PF05110.13 ORY89431.1 - 0.0016 16.7 3.9 0.0016 16.7 3.9 4.1 2 1 2 4 4 4 1 AF-4 proto-oncoprotein Aminotran_1_2 PF00155.21 ORY89432.1 - 9.7e-37 127.0 0.0 1.1e-36 126.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY89432.1 - 0.09 12.0 0.1 0.19 11.0 0.1 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Filaggrin PF03516.13 ORY89432.1 - 0.89 10.3 4.2 4.7 8.0 1.3 2.4 2 0 0 2 2 2 0 Filaggrin Ferric_reduct PF01794.19 ORY89433.1 - 1.6e-19 70.2 12.7 3.6e-19 69.1 12.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY89433.1 - 2e-14 54.0 0.0 3.7e-11 43.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY89433.1 - 5.3e-09 36.1 0.0 2.9e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain HSF_DNA-bind PF00447.17 ORY89434.1 - 3.3e-11 43.7 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding zinc_ribbon_16 PF17034.5 ORY89435.1 - 5.4e-12 46.0 19.0 2e-09 37.7 19.0 2.5 1 1 0 1 1 1 1 Zinc-ribbon like family WD40 PF00400.32 ORY89435.1 - 0.00067 20.4 0.7 0.012 16.4 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ORY89435.1 - 2.5 7.8 15.4 1.1 8.9 11.7 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Ytp1 PF10355.9 ORY89436.1 - 8.1e-100 333.6 10.7 1.2e-99 333.0 10.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORY89436.1 - 4.4e-16 58.6 0.2 4.4e-16 58.6 0.2 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF2427) DUF1129 PF06570.11 ORY89436.1 - 3.8 6.9 9.5 0.15 11.5 0.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) Ytp1 PF10355.9 ORY89437.1 - 3.4e-99 331.5 6.6 4.7e-99 331.1 6.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 ORY89437.1 - 5.2e-16 58.3 0.4 5.2e-16 58.3 0.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) DUF1129 PF06570.11 ORY89437.1 - 0.14 11.7 3.3 0.11 12.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) zf-RING_2 PF13639.6 ORY89438.1 - 1e-06 28.9 5.3 1e-06 28.9 5.3 1.9 2 1 0 2 2 1 1 Ring finger domain SWIM PF04434.17 ORY89438.1 - 0.00015 21.4 0.2 0.00027 20.5 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger Prok-RING_1 PF14446.6 ORY89438.1 - 0.025 14.5 4.3 0.18 11.8 4.3 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 ORY89438.1 - 0.036 14.3 3.7 0.036 14.3 3.7 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 ORY89438.1 - 0.038 13.8 4.8 0.092 12.6 4.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY89438.1 - 0.041 13.9 4.3 0.1 12.7 2.8 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-PHD-like PF15446.6 ORY89438.1 - 0.05 13.2 0.9 0.05 13.2 0.9 1.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-Di19 PF05605.12 ORY89438.1 - 0.093 13.0 1.5 5.8 7.3 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 ORY89438.1 - 0.12 12.1 0.4 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 GAGA factor PHD PF00628.29 ORY89438.1 - 0.13 12.2 4.5 0.22 11.4 3.9 1.8 2 0 0 2 2 2 0 PHD-finger zf-rbx1 PF12678.7 ORY89438.1 - 0.38 11.1 7.4 1.7 9.0 7.4 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 ORY89438.1 - 0.72 10.2 5.3 0.19 12.0 1.6 2.0 2 1 0 2 2 2 0 RING-like domain zf-RING_11 PF17123.5 ORY89438.1 - 1.1 9.1 4.1 0.36 10.6 0.6 2.1 2 0 0 2 2 2 0 RING-like zinc finger MFS_1 PF07690.16 ORY89439.1 - 5.5e-32 111.1 52.4 4e-28 98.4 32.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89439.1 - 1.5e-29 103.2 24.3 1.9e-21 76.5 11.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter HAMP PF00672.25 ORY89440.1 - 5.5e-32 109.9 25.3 4.1e-08 33.5 0.4 8.1 7 2 2 9 9 9 4 HAMP domain HATPase_c PF02518.26 ORY89440.1 - 3.5e-31 108.0 0.1 1.4e-30 106.1 0.0 2.2 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY89440.1 - 5.3e-27 94.2 0.5 1.1e-23 83.6 0.4 3.0 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 ORY89440.1 - 2.5e-16 59.5 0.4 3.1e-15 56.0 0.4 3.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF3829 PF12889.7 ORY89440.1 - 5.8e-06 26.0 0.8 0.039 13.4 0.0 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3829) HATPase_c_3 PF13589.6 ORY89440.1 - 0.0082 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Syntaxin_2 PF14523.6 ORY89440.1 - 0.014 15.8 1.7 5.3 7.5 0.0 4.5 1 1 2 4 4 4 0 Syntaxin-like protein ApoLp-III PF07464.11 ORY89440.1 - 0.051 13.7 19.8 0.12 12.5 1.1 5.4 1 1 4 6 6 6 0 Apolipophorin-III precursor (apoLp-III) SpoIIID PF12116.8 ORY89440.1 - 0.055 13.6 0.2 7.2 6.8 0.0 3.3 3 0 0 3 3 3 0 Stage III sporulation protein D GatB_Yqey PF02637.18 ORY89440.1 - 0.085 12.7 2.0 0.86 9.5 0.1 2.9 2 0 0 2 2 2 0 GatB domain FtsJ PF01728.19 ORY89440.1 - 0.097 12.8 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase DUF948 PF06103.11 ORY89440.1 - 1.9 8.8 39.5 2.8 8.3 0.9 7.8 2 2 4 6 6 6 0 Bacterial protein of unknown function (DUF948) TF_Zn_Ribbon PF08271.12 ORY89441.1 - 0.17 11.4 0.4 0.28 10.7 0.4 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding DUF3808 PF10300.9 ORY89442.1 - 1.9e-71 241.3 0.0 2.8e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Gly_rich PF12810.7 ORY89442.1 - 0.015 15.2 6.7 0.024 14.6 6.7 1.2 1 0 0 1 1 1 0 Glycine rich protein zf-C2H2 PF00096.26 ORY89443.1 - 6.3e-09 35.8 10.2 8e-06 26.0 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY89443.1 - 3.1e-06 27.4 11.4 4.2e-06 26.9 2.7 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY89443.1 - 7.3e-06 26.4 9.2 0.0001 22.8 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY89443.1 - 0.024 14.4 0.8 0.054 13.3 0.8 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type Ogr_Delta PF04606.12 ORY89443.1 - 0.033 14.2 1.4 0.65 10.0 0.0 2.3 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_8 PF15909.5 ORY89443.1 - 0.041 14.2 0.6 0.14 12.5 0.6 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 ORY89443.1 - 0.048 13.6 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 ORY89443.1 - 0.069 13.5 1.9 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY89443.1 - 0.078 13.0 4.1 0.14 12.2 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-UBP PF02148.19 ORY89443.1 - 3.1 8.2 6.2 5.3 7.5 0.6 2.3 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-H2C2_2 PF13465.6 ORY89444.1 - 0.00068 20.0 0.8 0.0012 19.2 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger double domain F-box-like PF12937.7 ORY89444.1 - 0.0047 16.8 0.7 0.011 15.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY89444.1 - 1.4 9.5 7.3 15 6.2 0.9 3.5 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 ORY89445.1 - 5e-50 169.7 2.4 6e-50 169.4 2.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY89445.1 - 1e-33 116.9 1.8 1.3e-33 116.5 1.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY89445.1 - 2.2e-12 47.2 1.9 3.1e-12 46.8 1.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY89445.1 - 1e-05 25.1 1.2 1.9e-05 24.3 1.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY89445.1 - 5.3e-05 22.5 0.4 6.1e-05 22.3 0.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 ORY89445.1 - 0.0008 18.9 0.6 0.0011 18.5 0.6 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 ORY89445.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.19 ORY89445.1 - 0.018 14.4 0.4 0.054 12.9 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY89445.1 - 0.021 14.7 0.6 0.037 13.9 0.6 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 ORY89445.1 - 0.025 13.9 0.2 0.054 12.8 0.2 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 ORY89445.1 - 0.089 13.2 1.2 0.21 12.0 0.7 2.0 2 1 0 2 2 2 0 Putative NAD(P)-binding NUDIX PF00293.28 ORY89446.1 - 5.1e-15 55.7 1.3 6.6e-15 55.3 0.4 1.6 2 0 0 2 2 2 1 NUDIX domain MRP-L46 PF11788.8 ORY89446.1 - 1.1e-12 48.7 0.1 2e-12 47.9 0.1 1.6 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 GPI2 PF06432.11 ORY89447.1 - 2.2e-69 234.0 0.1 3e-69 233.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Ubie_methyltran PF01209.18 ORY89448.1 - 1.1e-84 283.4 0.0 1.4e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY89448.1 - 4.2e-16 59.4 0.0 8.1e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY89448.1 - 6e-14 52.1 0.0 8.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY89448.1 - 1.8e-13 51.0 0.0 3.5e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY89448.1 - 1.9e-10 41.4 0.0 3.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY89448.1 - 2.4e-05 24.2 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 ORY89448.1 - 0.031 14.1 0.0 0.11 12.3 0.0 1.8 1 1 1 2 2 2 0 Hypothetical methyltransferase Abhydrolase_1 PF00561.20 ORY89450.1 - 6e-24 85.1 0.0 1.2e-22 80.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY89450.1 - 5.7e-14 53.2 0.1 6.9e-14 53.0 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY89450.1 - 0.00011 21.6 0.0 0.071 12.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORY89450.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme p450 PF00067.22 ORY89451.1 - 1.5e-79 268.0 0.0 2.1e-79 267.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CAP59_mtransfer PF11735.8 ORY89452.1 - 8.8e-69 231.9 0.0 1.1e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Abhydrolase_2 PF02230.16 ORY89453.1 - 6.9e-33 114.3 0.0 1e-32 113.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORY89453.1 - 3.3e-05 23.7 0.0 5.5e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ORY89453.1 - 0.15 11.3 0.1 4.1 6.6 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORY89453.1 - 0.18 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) O-FucT PF10250.9 ORY89454.1 - 3.4e-13 50.0 0.0 6.7e-13 49.0 0.0 1.5 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Chromo PF00385.24 ORY89455.1 - 6.3e-15 54.8 0.3 1.1e-14 54.0 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 ORY89455.1 - 0.00092 19.3 0.4 0.0017 18.5 0.4 1.4 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 Gti1_Pac2 PF09729.9 ORY89456.1 - 5.4e-33 114.6 1.1 5.8e-30 104.7 0.1 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family Peptidase_M20 PF01546.28 ORY89457.1 - 8.6e-33 113.8 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY89457.1 - 1.6e-11 44.1 0.0 3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Rif1_N PF12231.8 ORY89458.1 - 2.7e-05 23.3 0.0 0.0001 21.5 0.0 1.8 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Sugar_tr PF00083.24 ORY89459.1 - 3.8e-50 171.1 14.5 5.1e-50 170.6 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY89459.1 - 1.4e-19 70.3 25.4 1.4e-19 70.3 25.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily FtsJ PF01728.19 ORY89460.1 - 1.1e-71 240.6 0.0 1.4e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Glyco_transf_90 PF05686.12 ORY89461.1 - 2.1e-15 56.6 6.1 3.6e-15 55.8 0.1 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 DUF775 PF05603.12 ORY89462.1 - 8.2e-50 169.1 0.0 9e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF2385 PF09539.10 ORY89463.1 - 0.012 16.1 0.1 0.029 14.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) DUF1635 PF07795.11 ORY89463.1 - 0.083 12.7 2.2 0.19 11.5 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) CMAS PF02353.20 ORY89465.1 - 4.6e-67 226.2 0.2 5.6e-67 225.9 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY89465.1 - 3.6e-10 40.4 0.0 1.1e-09 38.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY89465.1 - 1.4e-09 38.4 0.0 5.6e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY89465.1 - 4.3e-08 33.2 0.0 7.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY89465.1 - 2.5e-06 28.1 0.0 4.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY89465.1 - 6.9e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 ORY89465.1 - 0.00018 21.1 0.0 0.00053 19.6 0.0 1.8 1 1 1 2 2 2 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 ORY89465.1 - 0.00024 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY89465.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ORY89465.1 - 0.056 12.8 0.0 0.086 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 ORY89465.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DS PF01916.17 ORY89466.1 - 1.7e-131 437.8 0.0 1.9e-131 437.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase His_Phos_2 PF00328.22 ORY89467.1 - 2.4e-85 287.2 0.1 3.1e-85 286.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 ORY89467.1 - 1.7e-37 127.4 0.0 4e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 ORY89467.1 - 3.5e-08 33.3 0.0 7e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Sedlin_N PF04628.13 ORY89468.1 - 2.4e-18 66.5 0.0 3.1e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L44 PF00935.19 ORY89469.1 - 6.2e-37 125.9 11.4 9.5e-37 125.3 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Cathelicidins PF00666.17 ORY89469.1 - 0.032 14.5 0.6 0.056 13.8 0.6 1.3 1 0 0 1 1 1 0 Cathelicidin Ribosomal_L44 PF00935.19 ORY89470.1 - 1.9e-11 44.3 1.5 1.9e-11 44.3 1.5 2.0 3 0 0 3 3 3 1 Ribosomal protein L44 ACPS PF01648.20 ORY89471.1 - 7.9e-15 55.0 0.0 2.2e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Glyco_hydro_63 PF03200.16 ORY89472.1 - 1.3e-170 568.4 0.0 1.1e-169 565.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 ORY89472.1 - 1.9e-68 231.0 0.0 3.2e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 ORY89472.1 - 0.00039 19.4 0.0 0.00073 18.5 0.0 1.3 1 0 0 1 1 1 1 Trehalase PepSY_2 PF13670.6 ORY89472.1 - 0.069 13.2 0.2 0.19 11.7 0.2 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2141 PF09912.9 ORY89472.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2141) PARP PF00644.20 ORY89473.1 - 9.3e-11 41.7 0.1 1.9e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 ORY89473.1 - 3.7e-08 33.1 0.1 1.5e-07 31.1 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme CAP59_mtransfer PF11735.8 ORY89475.1 - 2.1e-30 106.2 0.0 3.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Tic110 PF16940.5 ORY89475.1 - 3.1 6.2 4.8 4.1 5.8 4.8 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter TFIID-18kDa PF02269.16 ORY89476.1 - 6.6e-25 87.0 0.0 1.2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit WD40 PF00400.32 ORY89477.1 - 4e-27 93.9 20.4 0.00012 22.8 0.0 10.4 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89477.1 - 3.7e-07 30.3 0.6 4.7 7.6 0.0 6.4 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIE-A_C PF11521.8 ORY89477.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Pkinase PF00069.25 ORY89478.1 - 2.5e-52 177.8 0.0 3.1e-32 112.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89478.1 - 2e-19 69.9 0.0 1.7e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 ORY89478.1 - 0.001 19.0 0.9 0.001 19.0 0.9 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY89478.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 ORY89478.1 - 0.047 13.0 0.1 0.4 10.0 0.0 2.3 3 0 0 3 3 3 0 Kinase-like RNase_P_p30 PF01876.16 ORY89478.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit p30 DJ-1_PfpI PF01965.24 ORY89479.1 - 2.8e-14 53.3 0.0 6.6e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY89479.1 - 0.0022 17.7 0.1 0.012 15.3 0.1 2.2 1 1 0 1 1 1 1 ThiJ/PfpI family-like DUF202 PF02656.15 ORY89480.1 - 8.6e-17 61.3 0.0 2.3e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) IMD PF08397.11 ORY89481.1 - 0.037 13.4 0.4 0.058 12.8 0.4 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain GHL13 PF14883.6 ORY89481.1 - 0.049 12.7 0.6 0.074 12.1 0.6 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 APG6_N PF17675.1 ORY89481.1 - 0.13 12.8 3.6 0.29 11.7 3.6 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Polysacc_deac_1 PF01522.21 ORY89482.1 - 2e-10 40.6 0.0 4.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase FAM209 PF15206.6 ORY89483.1 - 0.061 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 FAM209 family zf-C6H2 PF15801.5 ORY89483.1 - 0.91 9.9 7.7 2.4 8.5 7.7 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Sec2p PF06428.11 ORY89484.1 - 1.1e-11 44.5 10.4 1.1e-11 44.5 10.4 3.4 4 1 0 4 4 4 1 GDP/GTP exchange factor Sec2p PSCyt3 PF07627.11 ORY89484.1 - 0.031 14.5 0.4 2.5 8.4 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Baculo_PEP_C PF04513.12 ORY89484.1 - 0.32 11.0 2.7 15 5.6 0.0 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MbeD_MobD PF04899.12 ORY89484.1 - 0.54 10.4 5.1 0.39 10.9 0.2 2.8 2 1 1 3 3 3 0 MbeD/MobD like NDUFA12 PF05071.16 ORY89485.1 - 4.6e-29 101.1 2.3 5.7e-29 100.8 2.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 E1-E2_ATPase PF00122.20 ORY89486.1 - 1.9e-32 112.3 9.9 5.7e-30 104.2 0.8 3.5 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY89486.1 - 6.4e-25 87.9 5.0 6.4e-25 87.9 5.0 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY89486.1 - 1.6e-17 63.4 0.0 3.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY89486.1 - 1.5e-16 61.4 0.4 6.2e-13 49.5 0.2 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY89486.1 - 4.9e-15 55.0 0.0 1.1e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY89486.1 - 0.0002 21.2 1.0 0.00098 18.9 0.9 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DSPc PF00782.20 ORY89488.1 - 1.6e-28 99.2 0.0 2.5e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY89488.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY89488.1 - 0.025 14.7 0.2 0.056 13.6 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 ORY89488.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF908 PF06012.12 ORY89488.1 - 0.61 9.4 2.7 1 8.7 2.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) zf-MYND PF01753.18 ORY89489.1 - 0.0086 16.1 13.0 0.017 15.2 13.0 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY89490.1 - 0.048 14.0 6.2 0.13 12.6 6.2 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 ORY89490.1 - 0.072 13.2 7.6 0.18 11.9 7.6 1.8 1 0 0 1 1 1 0 MYND finger KxDL PF10241.9 ORY89490.1 - 0.077 13.3 1.0 0.13 12.5 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Mrr_N PF14338.6 ORY89490.1 - 0.13 12.4 0.5 0.56 10.4 0.5 2.1 1 1 0 1 1 1 0 Mrr N-terminal domain Pkinase PF00069.25 ORY89491.1 - 4.6e-65 219.6 0.0 6e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89491.1 - 3.3e-29 102.0 0.0 4.9e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY89491.1 - 1.8e-15 57.4 3.1 6.8e-15 55.5 3.1 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 ORY89491.1 - 1.1e-08 35.3 0.0 3.4e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 ORY89491.1 - 2.9e-06 26.8 0.0 2.6e-05 23.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY89491.1 - 4.5e-05 22.6 0.0 6.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY89491.1 - 0.033 13.8 0.1 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY89491.1 - 0.038 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vac_Fusion PF02346.16 ORY89586.1 - 0.082 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Ku PF02735.16 ORY89587.1 - 1.3e-38 132.7 0.0 4.5e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ORY89587.1 - 6.8e-20 71.8 0.0 1.5e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 ORY89587.1 - 5.2e-17 62.3 1.2 5.2e-17 62.3 1.2 3.0 1 1 1 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 ORY89587.1 - 5.1e-08 32.5 0.2 2.2e-07 30.5 0.2 2.2 1 0 0 1 1 1 1 SAP domain NPA PF16469.5 ORY89587.1 - 0.088 13.4 0.1 0.27 11.8 0.1 1.8 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 CAP_GLY PF01302.25 ORY89588.1 - 2.1e-19 69.3 0.3 3.7e-19 68.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain HAP1_N PF04849.13 ORY89588.1 - 0.00023 20.5 7.7 0.00023 20.5 7.7 4.3 4 0 0 4 4 4 1 HAP1 N-terminal conserved region CLIP1_ZNF PF16641.5 ORY89588.1 - 0.00027 20.7 6.8 0.00027 20.7 6.8 2.7 2 0 0 2 2 2 1 CLIP1 zinc knuckle DUF1515 PF07439.11 ORY89588.1 - 0.0043 17.1 1.5 0.0043 17.1 1.5 5.9 5 1 2 7 7 7 1 Protein of unknown function (DUF1515) zf-CCHC_4 PF14392.6 ORY89588.1 - 0.063 13.0 4.3 0.87 9.4 0.3 2.5 2 0 0 2 2 2 0 Zinc knuckle Exonuc_VII_L PF02601.15 ORY89588.1 - 9.9 5.6 56.2 4.5 6.7 8.8 4.4 2 1 2 4 4 4 0 Exonuclease VII, large subunit DEAD PF00270.29 ORY89590.1 - 6.3e-38 130.3 0.0 1.5e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY89590.1 - 5.1e-28 97.6 0.0 2.9e-26 92.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 ORY89590.1 - 1e-17 64.1 0.2 3.7e-17 62.3 0.2 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 ORY89590.1 - 0.00024 21.1 0.0 0.0006 19.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Asp PF00026.23 ORY89591.1 - 4.1e-54 184.1 2.4 5e-54 183.9 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY89591.1 - 4.7e-06 26.9 3.0 0.0011 19.2 3.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY89591.1 - 0.0026 17.5 0.0 0.017 14.9 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY89591.1 - 0.011 16.3 1.3 0.34 11.6 0.4 3.0 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 ORY89591.1 - 0.087 13.4 0.3 3.8 8.1 0.1 3.0 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease COPI_C PF06957.11 ORY89592.1 - 8.8 5.0 7.2 13 4.4 7.2 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus zf-C2H2 PF00096.26 ORY89593.1 - 1.6e-09 37.7 3.4 0.00069 19.9 0.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY89593.1 - 1.3e-05 25.6 2.5 0.0088 16.8 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY89593.1 - 0.0023 18.3 6.2 0.38 11.3 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain SAP PF02037.27 ORY89595.1 - 6.6e-11 41.7 5.8 2.5e-10 39.9 1.5 2.3 2 0 0 2 2 2 2 SAP domain Telomere_Sde2_2 PF13297.6 ORY89595.1 - 0.0016 18.0 1.4 0.0026 17.4 0.2 1.9 2 0 0 2 2 2 1 Telomere stability C-terminal DUF4245 PF14030.6 ORY89595.1 - 0.37 10.8 9.9 0.03 14.4 4.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4245) Pyridoxal_deC PF00282.19 ORY89596.1 - 2.3e-22 79.3 0.0 3.4e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY89596.1 - 2.6e-08 33.2 0.0 5.7e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY89596.1 - 2.8e-05 23.6 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORY89596.1 - 0.1 11.1 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme WD40 PF00400.32 ORY89598.1 - 2.9e-07 31.1 5.7 0.00061 20.6 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat CBFD_NFYB_HMF PF00808.23 ORY89599.1 - 8.3e-10 38.8 0.4 8.3e-10 38.8 0.4 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AA_permease_2 PF13520.6 ORY89600.1 - 7.5e-51 173.3 51.3 9.7e-51 172.9 51.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY89600.1 - 2.8e-28 98.7 44.3 3.8e-28 98.3 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 ORY89601.1 - 4.3e-26 91.9 0.0 1.7e-24 86.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89601.1 - 1.2e-15 57.5 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY89601.1 - 0.041 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Beta-lactamase PF00144.24 ORY89602.1 - 3.5e-52 177.7 0.6 5.4e-52 177.1 0.6 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ORY89602.1 - 0.021 15.3 0.0 0.045 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.6 ORY89602.1 - 0.031 13.9 0.0 0.074 12.6 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase enzyme family Gpr1_Fun34_YaaH PF01184.19 ORY89603.1 - 6.4e-44 150.0 13.6 8e-44 149.7 13.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 ORY89604.1 - 2e-42 145.1 18.0 2.5e-42 144.8 18.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3844 PF12955.7 ORY89605.1 - 6.6e-26 90.5 0.5 1.1e-25 89.8 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) F-box-like PF12937.7 ORY89606.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like TAL_effector PF03377.13 ORY89606.1 - 0.21 12.0 2.5 0.22 11.9 0.6 2.1 2 0 0 2 2 2 0 TAL effector repeat 2-Hacid_dh_C PF02826.19 ORY89607.1 - 1.3e-43 148.4 0.0 2.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY89607.1 - 1.3e-19 70.1 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 ORY89607.1 - 0.017 14.5 0.0 0.25 10.6 0.0 2.1 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF5029 PF16432.5 ORY89607.1 - 0.059 12.9 0.4 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5029) P3A PF08727.11 ORY89607.1 - 0.17 11.3 0.0 25 4.4 0.0 2.5 2 0 0 2 2 2 0 Poliovirus 3A protein like Sporozoite_P67 PF05642.11 ORY89608.1 - 3.8 5.5 17.7 4.4 5.3 17.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Muskelin_N PF06588.11 ORY89609.1 - 3.4e-46 157.7 0.2 1.3e-45 155.8 0.2 1.8 1 1 0 1 1 1 1 Muskelin N-terminus Kelch_5 PF13854.6 ORY89609.1 - 3.2e-17 62.1 0.1 0.00021 21.2 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 ORY89609.1 - 4.1e-12 46.1 8.2 0.0016 18.7 1.0 6.8 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY89609.1 - 1.4e-08 34.7 3.2 0.09 13.1 0.1 6.2 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 ORY89609.1 - 1.2e-07 31.1 0.5 0.04 13.5 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 ORY89609.1 - 7.3e-06 25.8 8.1 0.0051 16.7 0.0 5.2 6 0 0 6 6 6 2 Kelch motif GCS PF03074.16 ORY89610.1 - 3.4e-174 579.4 0.0 4.3e-174 579.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Alpha-amylase PF00128.24 ORY89611.1 - 4.9e-25 88.8 2.8 1.1e-24 87.6 2.8 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 ORY89611.1 - 0.00018 19.9 0.0 0.095 10.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.10 ORY89611.1 - 0.0018 18.4 0.5 0.0047 17.1 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) MFA1_2 PF17317.2 ORY89611.1 - 0.033 14.0 0.1 0.082 12.7 0.1 1.7 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 Mito_carr PF00153.27 ORY89612.1 - 6.4e-61 202.3 3.7 2.1e-22 78.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein eIF-5_eIF-2B PF01873.17 ORY89613.1 - 8.9e-42 141.7 0.1 1.2e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ORY89613.1 - 0.00023 20.6 0.2 0.00037 19.9 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding IF2_N PF04760.15 ORY89613.1 - 0.024 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region RNA_pol_L PF01193.24 ORY89613.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF2752 PF10825.8 ORY89613.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) zf-HYPF PF07503.12 ORY89613.1 - 0.16 11.8 1.1 7.8 6.4 0.0 2.9 3 0 0 3 3 3 0 HypF finger Rad10 PF03834.14 ORY89614.1 - 1.2e-44 151.0 0.7 1.6e-44 150.5 0.7 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 ORY89614.1 - 5.1e-09 36.6 0.0 9.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.7 ORY89614.1 - 0.0029 17.7 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_34 PF13601.6 ORY89614.1 - 0.13 12.4 0.0 0.79 9.9 0.0 2.1 2 0 0 2 2 2 0 Winged helix DNA-binding domain PTPLA PF04387.14 ORY89614.1 - 0.15 11.8 0.4 0.26 11.0 0.2 1.5 1 1 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA Beta_helix PF13229.6 ORY89615.1 - 2.7e-06 27.3 0.2 1.2e-05 25.2 0.2 2.1 1 1 0 1 1 1 1 Right handed beta helix region B_lectin PF01453.24 ORY89615.1 - 0.18 12.4 0.0 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 D-mannose binding lectin zf-CCCH PF00642.24 ORY89616.1 - 5.6e-12 45.3 12.7 9.7e-07 28.6 1.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY89616.1 - 0.00012 22.0 8.4 0.00086 19.3 1.1 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 ORY89616.1 - 0.00075 19.3 0.1 0.043 13.6 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 ORY89616.1 - 0.0057 17.3 2.1 0.68 10.7 0.2 2.5 3 0 0 3 3 3 2 Torus domain Use1 PF09753.9 ORY89617.1 - 1.1e-17 64.6 0.1 1.4e-16 61.0 0.0 2.1 2 0 0 2 2 2 1 Membrane fusion protein Use1 Mt_ATP-synt_B PF05405.14 ORY89617.1 - 0.17 11.5 0.9 0.34 10.5 0.9 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Asp PF00026.23 ORY89618.1 - 1.9e-73 247.6 7.9 2.4e-73 247.3 7.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY89618.1 - 6.1e-13 49.4 7.7 4.2e-10 40.2 6.1 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY89618.1 - 0.00032 20.5 0.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY89618.1 - 0.0029 18.2 0.2 5.9 7.6 0.0 3.2 2 2 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY89618.1 - 0.14 12.7 0.2 27 5.4 0.0 3.0 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease 2-Hacid_dh_C PF02826.19 ORY89619.1 - 1.3e-43 148.5 0.0 2.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY89619.1 - 1.8e-19 69.7 0.0 2.4e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 ORY89619.1 - 0.014 14.7 0.0 0.21 10.9 0.0 2.1 1 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF5029 PF16432.5 ORY89619.1 - 0.059 12.9 0.4 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5029) P3A PF08727.11 ORY89619.1 - 0.17 11.3 0.0 25 4.4 0.0 2.4 2 0 0 2 2 2 0 Poliovirus 3A protein like F-box-like PF12937.7 ORY89620.1 - 0.0029 17.5 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY89620.1 - 0.036 14.5 0.5 19 5.9 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) CitMHS PF03600.16 ORY89622.1 - 0.0013 18.0 1.0 0.0025 17.1 0.9 1.4 1 1 0 1 1 1 1 Citrate transporter Prefoldin_2 PF01920.20 ORY89623.1 - 3.2e-18 65.6 8.1 3.9e-18 65.4 8.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 ORY89623.1 - 0.00015 21.9 7.6 0.057 13.7 2.4 2.1 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF5623 PF18536.1 ORY89623.1 - 0.0031 17.8 0.6 0.0041 17.4 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5623) TPR_MLP1_2 PF07926.12 ORY89623.1 - 0.012 15.7 5.5 1.1 9.3 1.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 ORY89623.1 - 0.018 14.3 3.4 0.15 11.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Nas2_N PF18265.1 ORY89623.1 - 0.027 14.4 4.2 1.6 8.7 1.5 2.4 2 0 0 2 2 2 0 Nas2 N_terminal domain NPV_P10 PF05531.12 ORY89623.1 - 0.03 14.8 2.3 0.3 11.6 0.8 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 ORY89623.1 - 0.033 14.4 9.5 0.074 13.3 3.0 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 ORY89623.1 - 0.042 13.8 7.8 0.89 9.5 0.7 2.2 1 1 1 2 2 2 0 Prefoldin subunit MCC-bdg_PDZ PF10506.9 ORY89623.1 - 0.044 13.8 4.2 3.2 7.8 0.5 2.8 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DASH_Dad2 PF08654.10 ORY89623.1 - 0.047 14.1 3.9 1.3 9.5 0.6 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad2 DUF1640 PF07798.11 ORY89623.1 - 0.051 13.6 6.6 0.34 10.9 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) PCRF PF03462.18 ORY89623.1 - 0.073 12.9 5.9 0.093 12.6 5.9 1.1 1 0 0 1 1 1 0 PCRF domain DASH_Dad4 PF08650.10 ORY89623.1 - 0.084 12.9 1.7 0.23 11.5 0.4 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad4 Spc7 PF08317.11 ORY89623.1 - 0.1 11.4 7.5 0.14 11.0 7.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.18 ORY89623.1 - 0.11 12.7 5.6 0.39 11.0 0.9 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Sec20 PF03908.13 ORY89623.1 - 0.12 12.3 4.0 1.2 9.1 0.7 2.2 1 1 1 2 2 2 0 Sec20 Occludin_ELL PF07303.13 ORY89623.1 - 0.14 12.9 1.8 4.3 8.1 0.3 2.1 2 0 0 2 2 2 0 Occludin homology domain DUF2730 PF10805.8 ORY89623.1 - 0.14 12.2 4.1 0.6 10.2 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) ZapB PF06005.12 ORY89623.1 - 0.26 11.8 10.1 0.32 11.5 1.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Swi5 PF07061.11 ORY89623.1 - 0.32 11.1 4.9 7 6.8 0.8 2.3 2 0 0 2 2 2 0 Swi5 Rho_Binding PF08912.11 ORY89623.1 - 0.41 11.5 11.3 4.6 8.1 0.8 2.2 1 1 1 2 2 2 0 Rho Binding BST2 PF16716.5 ORY89623.1 - 0.42 11.2 6.6 1 10.0 0.3 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Syntaxin-6_N PF09177.11 ORY89623.1 - 0.48 11.0 7.0 15 6.2 7.0 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FlaC_arch PF05377.11 ORY89623.1 - 0.75 10.2 9.4 10 6.6 3.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DinB PF05163.12 ORY89623.1 - 1.3 8.9 4.2 1.7 8.5 1.5 1.9 1 1 1 2 2 2 0 DinB family YabA PF06156.13 ORY89623.1 - 1.9 9.2 9.5 12 6.5 9.5 1.9 1 1 0 1 1 1 0 Initiation control protein YabA DUF4140 PF13600.6 ORY89623.1 - 1.9 8.9 7.0 6.5 7.3 0.5 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 ORY89623.1 - 3.9 7.3 7.7 6.4 6.6 0.6 2.2 2 0 0 2 2 2 0 Septum formation initiator OGFr_N PF04664.13 ORY89624.1 - 5.3e-55 186.2 0.1 7.4e-55 185.7 0.1 1.1 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region MDH PF02315.16 ORY89624.1 - 0.0097 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Methanol dehydrogenase beta subunit TRCF PF03461.15 ORY89624.1 - 0.11 12.9 0.0 12 6.3 0.0 2.6 2 0 0 2 2 2 0 TRCF domain Ku_N PF03731.15 ORY89625.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Cyt-b5 PF00173.28 ORY89626.1 - 5.8e-12 45.6 0.0 7.4e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.7 ORY89627.1 - 1.4e-07 31.3 0.0 4.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY89627.1 - 0.013 15.4 0.0 0.043 13.7 0.0 2.0 1 0 0 1 1 1 0 F-box domain DUF1168 PF06658.12 ORY89629.1 - 9.4e-26 90.2 0.9 1.2e-25 89.9 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) F-box PF00646.33 ORY89630.1 - 2.4e-09 36.8 3.9 5.3e-09 35.7 3.9 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY89630.1 - 5.3e-07 29.4 3.4 1.4e-06 28.1 3.4 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 ORY89630.1 - 0.0012 19.6 0.8 0.18 12.8 0.1 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat F-box_4 PF15966.5 ORY89630.1 - 0.009 15.9 0.3 0.016 15.1 0.3 1.4 1 0 0 1 1 1 1 F-box GCP_N_terminal PF17681.1 ORY89632.1 - 3.6e-86 289.6 0.0 1.5e-85 287.5 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY89632.1 - 2.2e-84 283.6 1.9 3.1e-84 283.1 1.9 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal RRM_1 PF00076.22 ORY89633.1 - 5.3e-17 61.4 0.0 9.8e-17 60.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 ORY89635.1 - 0.25 11.2 4.4 0.56 10.1 4.4 1.6 1 1 0 1 1 1 0 CCCH-type zinc finger HlyIII PF03006.20 ORY89636.1 - 9.3e-41 140.0 17.5 6e-40 137.3 17.5 1.8 1 1 0 1 1 1 1 Haemolysin-III related TF_Otx PF03529.13 ORY89636.1 - 0.27 11.6 4.3 0.72 10.3 4.3 1.7 1 0 0 1 1 1 0 Otx1 transcription factor MerC PF03203.14 ORY89636.1 - 1.4 9.4 11.1 1.4 9.4 0.6 3.3 2 1 1 3 3 3 0 MerC mercury resistance protein F-box PF00646.33 ORY89638.1 - 0.038 13.9 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY89638.1 - 0.097 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 F-box-like tRNA-synt_2 PF00152.20 ORY89639.1 - 1e-60 205.5 0.2 3.8e-59 200.3 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY89639.1 - 8.9e-11 41.6 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY89639.1 - 8.1e-07 28.8 0.0 0.0057 16.2 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Trm112p PF03966.16 ORY89640.1 - 8.8e-16 58.3 0.0 1.4e-15 57.6 0.0 1.4 1 1 0 1 1 1 1 Trm112p-like protein A2L_zn_ribbon PF08792.10 ORY89640.1 - 0.054 13.2 0.6 0.22 11.3 0.3 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_4 PF13717.6 ORY89640.1 - 0.061 13.2 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 ORY89640.1 - 0.15 11.5 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain FlgN PF05130.12 ORY89641.1 - 2.2 8.8 6.0 0.85 10.1 0.0 2.4 2 0 0 2 2 2 0 FlgN protein SNF2_N PF00176.23 ORY89642.1 - 1.7e-54 184.9 0.1 5.1e-54 183.3 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY89642.1 - 1.4e-17 64.0 0.0 7.9e-16 58.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY89642.1 - 3.4e-11 43.4 0.0 1.2e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1765 PF08578.10 ORY89643.1 - 5.6e-30 104.4 0.1 8.1e-30 103.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) P2_Phage_GpR PF06891.11 ORY89644.1 - 0.15 12.2 1.2 0.71 10.0 0.2 2.6 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) PspA_IM30 PF04012.12 ORY89645.1 - 0.077 12.6 4.7 0.087 12.4 0.9 2.1 2 0 0 2 2 2 0 PspA/IM30 family TFB6 PF17110.5 ORY89645.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Polysacc_deac_1 PF01522.21 ORY89646.1 - 7.4e-27 93.7 0.0 1.2e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY89646.1 - 0.013 14.7 0.1 0.073 12.3 0.0 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 RRM_1 PF00076.22 ORY89647.1 - 1.9e-05 24.4 0.0 5.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY89647.1 - 0.027 14.3 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 Occluded RNA-recognition motif Asp PF00026.23 ORY89648.1 - 5.7e-61 206.7 0.1 7.9e-61 206.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease KH_6 PF15985.5 ORY89648.1 - 1.1e-10 41.6 0.1 2.7e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 KH domain TAXi_N PF14543.6 ORY89648.1 - 3.5e-06 27.4 0.7 0.0049 17.1 0.1 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Myb_DNA-binding PF00249.31 ORY89651.1 - 9.9e-11 41.7 0.1 2.7e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORY89651.1 - 2.3e-08 33.7 4.2 1.3e-07 31.3 4.2 2.1 1 1 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 ORY89651.1 - 0.00047 20.3 0.0 0.00096 19.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 ORY89651.1 - 0.016 15.6 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 SWIRM domain TAP35_44 PF07265.11 ORY89651.1 - 0.46 10.5 1.7 0.9 9.6 1.7 1.5 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 RRM_1 PF00076.22 ORY89653.1 - 0.0026 17.5 0.1 5.3 6.9 0.1 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt PF00231.19 ORY89654.1 - 5.5e-77 259.2 8.5 6.2e-77 259.0 8.5 1.0 1 0 0 1 1 1 1 ATP synthase TGT PF01702.18 ORY89655.1 - 9.6e-121 403.2 0.0 1.1e-120 403.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.16 ORY89658.1 - 3.8e-23 82.0 40.6 2.5e-22 79.3 33.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89658.1 - 1.9e-08 33.6 1.3 1.9e-08 33.6 1.3 3.6 2 1 2 4 4 4 3 Sugar (and other) transporter TRI12 PF06609.13 ORY89658.1 - 1.2e-05 24.0 6.0 1.2e-05 24.0 6.0 2.5 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 ORY89659.1 - 2.4e-45 154.4 0.5 3.3e-45 154.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY89659.1 - 4.5e-33 114.8 0.4 5.9e-33 114.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY89659.1 - 2.5e-10 40.5 0.6 4.5e-10 39.7 0.6 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY89659.1 - 0.002 17.3 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 ORY89659.1 - 0.064 13.0 0.2 0.33 10.7 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pheromone PF08015.11 ORY89660.1 - 0.033 15.2 1.2 0.13 13.3 0.1 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone F-box PF00646.33 ORY89661.1 - 0.00018 21.3 0.7 0.51 10.3 0.1 2.9 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 ORY89661.1 - 0.052 13.5 2.2 1.3 9.0 0.0 3.4 3 1 0 3 3 3 0 F-box-like DUF411 PF04214.13 ORY89661.1 - 0.077 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF dCMP_cyt_deam_1 PF00383.23 ORY89662.1 - 2e-08 34.0 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PRP1_N PF06424.12 ORY89664.1 - 0.028 14.8 0.2 0.048 14.1 0.2 1.3 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Casc1_N PF15927.5 ORY89664.1 - 0.96 9.1 10.2 1.2 8.7 10.2 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus CAP_N PF01213.19 ORY89665.1 - 0.58 9.6 2.6 0.61 9.5 2.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 ORY89665.1 - 4.4 7.4 12.8 35 4.5 11.2 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Ribosomal_L27e PF01777.18 ORY89669.1 - 1.1e-36 125.0 0.8 1.4e-36 124.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 ORY89669.1 - 0.0029 17.5 0.0 0.012 15.5 0.0 2.1 1 0 0 1 1 1 1 KOW motif ABM PF03992.16 ORY89670.1 - 8e-09 35.5 0.0 1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Aldo_ket_red PF00248.21 ORY89671.1 - 4.8e-26 91.6 0.0 3.9e-22 78.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Met_asp_mut_E PF06368.11 ORY89671.1 - 0.22 10.0 0.0 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) zf-CCCH PF00642.24 ORY89675.1 - 1.3e-08 34.5 2.7 1.3e-08 34.5 2.7 2.7 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.6 ORY89675.1 - 9.9e-06 25.8 2.2 1.7e-05 25.0 2.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY89675.1 - 4e-05 23.5 2.6 7.8e-05 22.6 2.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY89675.1 - 4.1e-05 23.4 3.4 6.9e-05 22.7 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY89675.1 - 8.1e-05 22.4 1.1 0.00014 21.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 ORY89675.1 - 0.00014 21.8 4.3 0.00014 21.8 4.3 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-C3HC4_2 PF13923.6 ORY89675.1 - 0.0029 17.4 3.9 0.0051 16.6 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 ORY89675.1 - 0.0046 16.4 0.7 0.0046 16.4 0.7 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger zf-CCCH_4 PF18044.1 ORY89675.1 - 0.005 16.6 2.9 0.005 16.6 2.9 1.9 2 0 0 2 2 2 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 ORY89675.1 - 0.034 14.0 3.2 0.064 13.1 3.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY89675.1 - 0.056 13.2 0.5 0.098 12.4 0.5 1.4 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 ORY89675.1 - 0.13 12.6 1.2 0.3 11.4 1.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RanBP PF00641.18 ORY89675.1 - 1.6 8.1 4.0 0.74 9.2 1.2 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Aldo_ket_red PF00248.21 ORY89678.1 - 2.6e-22 79.4 0.0 7.3e-22 77.9 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Pterin_4a PF01329.19 ORY89681.1 - 1.5e-25 89.1 0.0 2e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase tRNA-synt_1g PF09334.11 ORY89682.1 - 9.7e-147 488.8 0.3 1.2e-146 488.5 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.20 ORY89682.1 - 2.8e-08 33.8 6.0 2.8e-08 33.8 6.0 1.8 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.22 ORY89682.1 - 1.6e-05 23.4 0.1 7.7e-05 21.1 0.0 2.2 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY89682.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF16 PF01519.16 ORY89682.1 - 0.0061 17.0 1.8 0.013 15.9 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF16 Mitoc_mL59 PF18126.1 ORY89682.1 - 2.4 8.5 5.8 5.9 7.2 5.8 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 DZR PF12773.7 ORY89682.1 - 6.8 6.8 8.5 26 5.0 4.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon Arrestin_N PF00339.29 ORY89683.1 - 9e-14 51.8 0.1 2.1e-12 47.3 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY89683.1 - 3.8e-13 50.0 0.7 3.2e-11 43.8 0.6 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.7 ORY89683.1 - 8.4e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like RdRP PF05183.12 ORY89684.1 - 7e-49 167.0 0.0 8.3e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase tRNA-synt_1b PF00579.25 ORY89685.1 - 5.3e-69 232.8 0.0 6.8e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 ORY89685.1 - 0.00027 20.6 0.0 0.00068 19.3 0.0 1.7 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 ORY89685.1 - 0.00064 19.5 0.2 0.0087 15.9 0.2 2.3 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Sugar_tr PF00083.24 ORY89686.1 - 4.2e-95 319.3 26.8 5.2e-95 319.0 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY89686.1 - 7.6e-17 61.3 39.5 7.6e-17 61.3 39.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY89686.1 - 5.4 5.2 11.1 0.1 10.8 0.3 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_S2 PF00318.20 ORY89687.1 - 4.9e-28 97.8 0.6 8.8e-15 54.5 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORY89687.1 - 1.5e-08 35.9 3.2 2.8e-08 35.0 3.2 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus SNAPc_SNAP43 PF09808.9 ORY89688.1 - 1.1e-07 32.0 0.0 2.9e-07 30.6 0.0 1.6 2 0 0 2 2 2 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 peroxidase PF00141.23 ORY89689.1 - 1.1e-49 169.2 0.0 1.8e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Transp_cyt_pur PF02133.15 ORY89690.1 - 2.1e-89 300.4 39.5 2.5e-89 300.1 39.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2OG-FeII_Oxy PF03171.20 ORY89691.1 - 1.9e-19 70.0 0.0 3.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 ORY89691.1 - 7e-17 62.3 0.1 1.1e-16 61.7 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4301 PF14134.6 ORY89691.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) SNAPc_SNAP43 PF09808.9 ORY89693.1 - 0.092 12.7 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 PHD PF00628.29 ORY89694.1 - 2.9e-06 27.1 13.8 4.9e-06 26.3 13.8 1.4 1 0 0 1 1 1 1 PHD-finger PROL5-SMR PF15621.6 ORY89694.1 - 0.3 11.6 0.1 0.3 11.6 0.1 4.1 4 0 0 4 4 4 0 Proline-rich submaxillary gland androgen-regulated family Abhydrolase_2 PF02230.16 ORY89695.1 - 2.1e-50 171.5 0.0 2.5e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 ORY89695.1 - 8.7e-08 31.7 0.1 0.0015 17.9 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 ORY89695.1 - 6.9e-07 29.0 0.0 9.6e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORY89695.1 - 1.7e-06 28.8 0.8 2.1e-06 28.5 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY89695.1 - 4.4e-05 23.0 0.1 0.00038 20.0 0.0 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORY89695.1 - 0.00013 21.9 0.4 0.33 10.8 0.2 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 ORY89695.1 - 0.00049 19.8 0.0 0.0028 17.4 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.20 ORY89695.1 - 0.0036 17.0 0.1 0.005 16.5 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Cutinase PF01083.22 ORY89695.1 - 0.0084 16.1 0.0 0.017 15.0 0.0 1.5 2 0 0 2 2 2 1 Cutinase LIP PF03583.14 ORY89695.1 - 0.0089 15.4 0.4 0.15 11.4 0.0 2.3 3 0 0 3 3 3 1 Secretory lipase Abhydrolase_1 PF00561.20 ORY89695.1 - 0.029 14.0 0.1 0.053 13.1 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 ORY89695.1 - 0.058 12.9 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.25 ORY89695.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Peptidase_M1 PF01433.20 ORY89696.1 - 5.1e-40 137.4 0.1 1.1e-39 136.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 ORY89696.1 - 6e-34 116.5 0.1 6e-34 116.5 0.1 1.8 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 ORY89696.1 - 2.3e-20 73.5 0.0 4e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Fungal_trans PF04082.18 ORY89697.1 - 3e-09 36.3 0.0 5.1e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY89697.1 - 1.6e-06 28.1 7.3 3.8e-06 26.9 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 ORY89697.1 - 5.4 6.9 13.0 8.1 6.3 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran PF00005.27 ORY89698.1 - 1.5e-16 61.2 0.0 3.3e-16 60.0 0.0 1.6 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY89698.1 - 7.3e-06 25.6 0.9 0.0094 15.4 0.0 3.1 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY89698.1 - 0.00013 21.8 0.2 0.038 13.8 0.0 2.6 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY89698.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 ORY89698.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.14 ORY89698.1 - 0.0034 17.4 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY89698.1 - 0.0039 17.4 0.0 0.0075 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY89698.1 - 0.0063 16.9 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORY89698.1 - 0.017 15.6 0.0 0.033 14.6 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ORY89698.1 - 0.019 14.7 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 ORY89698.1 - 0.025 15.1 0.1 0.049 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY89698.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 ORY89698.1 - 0.049 13.6 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORY89698.1 - 0.068 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 ORY89698.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Roc PF08477.13 ORY89698.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 ORY89698.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY89698.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 ORY89698.1 - 0.17 10.5 0.0 0.32 9.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 ORY89698.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain VWA_2 PF13519.6 ORY89699.1 - 0.12 13.1 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 von Willebrand factor type A domain RIX1 PF08167.12 ORY89699.1 - 0.17 11.6 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis SET PF00856.28 ORY89700.1 - 3.6e-15 56.7 0.0 2.5e-14 54.0 0.0 2.3 1 1 0 1 1 1 1 SET domain AWS PF17907.1 ORY89700.1 - 1.1e-11 44.5 7.2 2.2e-11 43.6 7.2 1.5 1 0 0 1 1 1 1 AWS domain PRIMA1 PF16101.5 ORY89700.1 - 0.11 12.6 7.8 9.3 6.3 4.9 2.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 ABC_membrane_2 PF06472.15 ORY89701.1 - 4.6e-95 318.1 2.9 7.2e-95 317.4 2.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY89701.1 - 1.8e-16 60.9 0.0 4e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY89701.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Tnp_22_trimer PF17489.2 ORY89701.1 - 0.046 13.7 1.3 1.7 8.7 0.6 2.5 2 0 0 2 2 2 0 L1 transposable element trimerization domain DUF815 PF05673.13 ORY89701.1 - 0.062 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AcMNPV_Ac109 PF05054.12 ORY89701.1 - 0.082 12.0 0.5 0.13 11.3 0.5 1.2 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein AAA_23 PF13476.6 ORY89701.1 - 0.094 13.2 4.5 0.22 12.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY89701.1 - 0.097 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY89701.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pterin_4a PF01329.19 ORY89702.1 - 2.8e-25 88.3 0.0 3.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase RRM_1 PF00076.22 ORY89703.1 - 1.9e-12 46.8 0.0 5.4e-05 22.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 ORY89703.1 - 0.082 12.9 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain Nuc_sug_transp PF04142.15 ORY89704.1 - 3.2e-90 302.5 8.6 2.5e-57 194.4 1.0 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 ORY89704.1 - 3.2e-05 24.1 4.1 3.2e-05 24.1 4.1 2.6 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 ORY89704.1 - 8.1e-05 22.0 1.6 8.1e-05 22.0 1.6 2.0 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 ORY89704.1 - 0.00016 21.0 0.1 0.00016 21.0 0.1 2.2 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.6 ORY89704.1 - 0.00032 20.4 2.3 0.0074 15.9 0.1 2.2 2 0 0 2 2 2 2 Putative multidrug resistance efflux transporter Multi_Drug_Res PF00893.19 ORY89704.1 - 0.092 13.4 0.6 0.092 13.4 0.6 2.4 2 0 0 2 2 2 0 Small Multidrug Resistance protein HIT PF01230.23 ORY89705.1 - 5.3e-15 56.0 0.0 1.1e-14 54.9 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 ORY89705.1 - 8.4e-07 29.5 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORY89705.1 - 0.23 11.3 0.2 0.42 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 PALP PF00291.25 ORY89706.1 - 2.4e-63 214.3 0.1 4.3e-31 108.4 0.1 2.1 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Methyltransf_31 PF13847.6 ORY89707.1 - 1.5e-05 24.9 0.0 2e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY89707.1 - 5e-05 22.9 0.1 0.00024 20.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY89707.1 - 0.0001 22.9 0.0 0.00058 20.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY89707.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 ORY89707.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 ORY89707.1 - 0.034 13.5 0.1 0.081 12.3 0.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 ORY89707.1 - 0.044 13.1 0.0 0.081 12.3 0.0 1.6 1 1 0 1 1 1 0 RNA methyltransferase Methyltransf_12 PF08242.12 ORY89707.1 - 0.046 14.5 0.0 0.29 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORY89707.1 - 0.052 13.4 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORY89707.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase N6_Mtase PF02384.16 ORY89707.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase ANAPC4_WD40 PF12894.7 ORY89708.1 - 0.0011 19.2 0.0 0.92 9.8 0.0 4.0 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY89708.1 - 0.0047 15.5 0.0 0.016 13.8 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain HPS6 PF15702.5 ORY89708.1 - 0.0097 14.0 0.0 0.015 13.3 0.0 1.2 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 6 protein PRKG1_interact PF15898.5 ORY89708.1 - 0.084 13.8 1.3 0.3 12.0 1.3 2.0 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain WD40 PF00400.32 ORY89708.1 - 0.22 12.4 3.3 6.9 7.7 0.1 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat F-box-like PF12937.7 ORY89709.1 - 0.0013 18.5 0.1 0.0035 17.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like EMP70 PF02990.16 ORY89710.1 - 3.5e-192 639.7 0.0 5.2e-192 639.1 0.0 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 CoA_binding_3 PF13727.6 ORY89710.1 - 0.31 11.1 7.0 0.16 11.9 3.0 2.4 2 0 0 2 2 2 0 CoA-binding domain F-box-like PF12937.7 ORY89711.1 - 1.3e-06 28.2 2.9 1.4e-06 28.0 0.9 2.2 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 ORY89711.1 - 0.0027 17.5 0.0 0.016 15.1 0.0 2.3 1 1 0 1 1 1 1 F-box domain Phage_AlpA PF05930.12 ORY89711.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Tannase PF07519.11 ORY89712.1 - 5.5e-93 312.4 0.1 7.4e-93 312.0 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 ORY89712.1 - 0.2 10.9 0.0 0.47 9.7 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Bromodomain PF00439.25 ORY89713.1 - 5.8e-23 80.8 0.3 9.5e-23 80.1 0.3 1.3 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 ORY89713.1 - 1.9e-08 34.6 0.1 4.3e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY89713.1 - 7.5e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY89713.1 - 0.0006 20.2 0.3 0.0012 19.2 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MIP PF00230.20 ORY89714.1 - 8.6e-27 94.3 12.8 1.2e-26 93.9 12.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein DUF1422 PF07226.11 ORY89714.1 - 5.7 7.0 6.9 2.9 7.9 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) Glyoxalase_3 PF13468.6 ORY89715.1 - 3.7e-23 82.5 0.0 2.5e-22 79.8 0.0 1.8 1 1 1 2 2 2 1 Glyoxalase-like domain Cu-oxidase_3 PF07732.15 ORY89716.1 - 4.6e-30 104.1 4.7 3.2e-23 82.0 3.1 3.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY89716.1 - 2.7e-27 95.2 0.8 6.7e-26 90.7 0.1 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 ORY89716.1 - 6.4e-24 84.9 0.2 9.1e-22 77.9 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Macoilin PF09726.9 ORY89716.1 - 6.5 5.2 4.7 9.2 4.7 4.7 1.1 1 0 0 1 1 1 0 Macoilin family Proteasome PF00227.26 ORY89717.1 - 2.8e-38 131.3 0.0 3.2e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RRM_1 PF00076.22 ORY89718.1 - 3e-09 36.5 0.0 7.7e-09 35.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 ORY89718.1 - 1e-08 35.0 0.1 2.7e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Surp module RRM_7 PF16367.5 ORY89718.1 - 0.00069 19.7 0.1 0.032 14.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif CTD_bind PF04818.13 ORY89718.1 - 0.00069 20.4 0.4 0.0017 19.1 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 ORY89718.1 - 0.025 14.6 0.0 0.04 13.9 0.0 1.2 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Zn_clus PF00172.18 ORY89719.1 - 4.9e-05 23.4 6.1 8.3e-05 22.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG27 PF09451.10 ORY89720.1 - 6e-62 209.9 0.0 8.1e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 ORY89720.1 - 1.1e-05 25.6 0.1 0.033 14.3 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 ORY89720.1 - 0.1 11.7 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Med14 PF08638.11 ORY89721.1 - 2.8e-57 193.2 0.0 4.3e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 APG6 PF04111.12 ORY89722.1 - 7.2e-48 162.9 0.0 2.9e-41 141.4 0.0 2.2 1 1 1 2 2 2 2 Apg6 BARA domain APG6_N PF17675.1 ORY89722.1 - 7.6e-25 88.0 3.4 1.1e-24 87.4 3.4 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region F-box-like PF12937.7 ORY89723.1 - 0.00019 21.3 0.2 0.00019 21.3 0.2 3.0 4 0 0 4 4 4 1 F-box-like F-box PF00646.33 ORY89723.1 - 0.0024 17.7 0.1 0.0024 17.7 0.1 2.5 3 0 0 3 3 3 1 F-box domain DUF2439 PF10382.9 ORY89724.1 - 2.2e-20 72.7 0.1 3.1e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) CASP_C PF08172.12 ORY89725.1 - 4.8e-73 245.6 0.2 4.8e-73 245.6 0.2 4.3 2 1 3 5 5 5 1 CASP C terminal DUF1664 PF07889.12 ORY89725.1 - 0.063 13.3 30.7 1.9 8.5 0.1 5.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) LIF_OSM PF01291.17 ORY89725.1 - 0.13 12.4 1.4 3.5 7.8 0.2 3.0 2 1 1 3 3 3 0 LIF / OSM family ALIX_LYPXL_bnd PF13949.6 ORY89725.1 - 0.43 9.8 47.5 0.33 10.2 21.5 3.6 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF4407 PF14362.6 ORY89725.1 - 2.1 7.6 50.0 0.24 10.7 14.9 4.4 1 1 4 5 5 5 0 Domain of unknown function (DUF4407) DUF2235 PF09994.9 ORY89726.1 - 1.1e-56 192.4 0.0 1.4e-56 192.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Cu-oxidase_3 PF07732.15 ORY89727.1 - 2.6e-44 150.0 2.5 6.7e-39 132.6 1.6 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY89727.1 - 3.1e-28 98.2 5.9 6.8e-26 90.6 0.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY89727.1 - 3.6e-26 92.2 0.0 6.1e-24 84.9 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase NAD_binding_10 PF13460.6 ORY89728.1 - 1.1e-11 44.9 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY89728.1 - 1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 ORY89728.1 - 3e-07 30.9 0.1 8.3e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.21 ORY89728.1 - 3.1e-07 30.1 0.0 0.00048 19.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ORY89728.1 - 6e-06 26.5 0.1 1.4e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 ORY89728.1 - 3.3e-05 24.0 0.0 5.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ORY89728.1 - 0.00021 21.5 0.0 0.00034 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 ORY89728.1 - 0.0014 17.7 0.0 0.0087 15.1 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORY89728.1 - 0.0021 18.3 0.1 0.0037 17.5 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ORY89728.1 - 0.0086 15.4 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GDP_Man_Dehyd PF16363.5 ORY89728.1 - 0.14 11.5 0.1 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Oxysterol_BP PF01237.18 ORY89729.1 - 1.5e-133 445.3 0.0 2.3e-133 444.6 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 ORY89729.1 - 5.1e-18 64.9 0.1 4.4e-10 39.6 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY89729.1 - 4.1e-17 62.6 0.0 2.5e-08 34.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY89729.1 - 2.3e-11 42.9 0.0 0.0064 16.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 ORY89729.1 - 3.5e-10 39.9 0.0 0.012 16.1 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 ORY89729.1 - 1.9e-09 37.9 0.0 0.00048 20.6 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 ORY89729.1 - 5.6e-08 33.2 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY89729.1 - 5.2e-05 23.6 0.3 0.0003 21.1 0.3 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 ORY89729.1 - 0.00039 20.6 0.1 0.00096 19.4 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain KxDL PF10241.9 ORY89729.1 - 0.14 12.4 0.7 14 6.0 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Ric8 PF10165.9 ORY89730.1 - 4e-78 263.5 0.0 8.7e-78 262.4 0.0 1.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn DUF3987 PF13148.6 ORY89730.1 - 2.8 6.8 11.2 4.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NAD_binding_6 PF08030.12 ORY89731.1 - 5.5e-27 94.8 0.0 8.9e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY89731.1 - 4.6e-18 65.3 0.0 1.3e-17 63.9 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 ORY89731.1 - 2.6e-17 63.1 11.8 2.6e-17 63.1 11.8 2.4 1 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 ORY89731.1 - 2.5e-05 24.9 0.0 0.00068 20.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Coatomer_b_Cpla PF14806.6 ORY89731.1 - 0.004 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Ntox3 PF15536.6 ORY89731.1 - 0.18 11.9 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial toxin 3 FAD_binding_6 PF00970.24 ORY89731.1 - 0.19 12.1 0.0 0.4 11.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Bestrophin PF01062.21 ORY89732.1 - 2.3e-30 106.0 0.1 9.6e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel NAD_binding_10 PF13460.6 ORY89733.1 - 4.8e-12 46.1 0.0 6.8e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY89733.1 - 3.2e-09 36.7 0.0 4.8e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 ORY89733.1 - 6.8e-09 35.5 0.0 2.3e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 ORY89733.1 - 9.3e-07 29.3 0.1 2.4e-06 28.0 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 ORY89733.1 - 7.1e-06 26.3 0.1 1.3e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 ORY89733.1 - 4.1e-05 22.7 0.0 0.00065 18.8 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 ORY89733.1 - 4.6e-05 23.5 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 ORY89733.1 - 0.00019 21.7 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY89733.1 - 0.00094 19.4 0.1 0.0016 18.7 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 ORY89733.1 - 0.0016 17.6 0.0 0.14 11.2 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain AlaDh_PNT_C PF01262.21 ORY89733.1 - 0.0092 15.3 0.2 0.013 14.8 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 ORY89733.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 ORY89733.1 - 0.086 12.2 0.2 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY89734.1 - 0.00056 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 ORY89734.1 - 0.01 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Tannase PF07519.11 ORY89735.1 - 5.2e-91 305.9 0.1 6.2e-91 305.6 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 ORY89735.1 - 0.025 14.0 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family MFS_1 PF07690.16 ORY89736.1 - 8.8e-19 67.6 46.0 1.2e-11 44.2 21.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY89736.1 - 2.3e-05 23.5 0.2 2.3e-05 23.5 0.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter ATP_bind_1 PF03029.17 ORY89737.1 - 4.1e-70 236.3 0.0 5e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 ORY89737.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 ORY89737.1 - 0.0074 16.4 0.0 0.013 15.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 ORY89737.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 ORY89737.1 - 0.054 12.9 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 ORY89737.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY89737.1 - 0.14 12.5 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY89737.1 - 0.14 11.9 0.7 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY89737.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bestrophin PF01062.21 ORY89738.1 - 5e-33 114.8 0.1 2.9e-21 76.1 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel KH_1 PF00013.29 ORY89740.1 - 1e-91 300.7 39.0 8.5e-11 41.5 0.0 12.9 13 1 0 13 13 13 11 KH domain SLS PF14611.6 ORY89740.1 - 4.3e-09 36.5 3.4 0.016 15.0 0.0 5.6 6 1 0 6 6 6 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 ORY89740.1 - 3.8e-08 33.0 35.1 0.73 9.7 0.4 9.8 10 0 0 10 10 10 5 KH domain FCD PF07729.12 ORY89740.1 - 0.0048 17.3 0.1 0.75 10.2 0.0 3.3 2 0 0 2 2 2 1 FCD domain SLBB PF10531.9 ORY89740.1 - 0.036 13.9 0.1 0.14 12.1 0.1 2.0 1 0 0 1 1 1 0 SLBB domain KH_4 PF13083.6 ORY89740.1 - 0.75 9.7 18.8 12 5.9 0.1 8.0 9 1 1 10 10 10 0 KH domain PCP_red PF08369.10 ORY89740.1 - 1.2 9.4 4.1 4.5 7.6 0.3 3.3 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit IF-2B PF01008.17 ORY89741.1 - 1.8e-47 161.9 0.0 2.6e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family L_lactis_ph-MCP PF06673.11 ORY89741.1 - 0.0028 16.7 0.0 0.012 14.6 0.0 1.8 2 0 0 2 2 2 1 Lactococcus lactis bacteriophage major capsid protein Acetate_kinase PF00871.17 ORY89742.1 - 5.6e-68 229.4 0.0 6.6e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF5557 PF17712.1 ORY89742.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5557) Piwi PF02171.17 ORY89743.1 - 3.3e-75 253.1 0.0 4.9e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORY89743.1 - 1.5e-15 58.0 0.0 2.8e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 ORY89743.1 - 1e-09 38.5 0.0 3.1e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 ORY89743.1 - 5.2e-09 36.3 0.0 1.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL1 PF08699.10 ORY89743.1 - 9.1e-09 34.9 0.0 2.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 ORY89743.1 - 0.012 15.5 0.0 0.043 13.6 0.0 1.8 1 1 0 1 1 1 0 PAZ domain DUF3543 PF12063.8 ORY89744.1 - 9.9e-67 224.9 0.4 1.9e-66 224.0 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 ORY89744.1 - 1.8e-58 198.0 0.0 3.7e-57 193.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89744.1 - 7.1e-40 136.9 0.0 2.2e-39 135.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY89744.1 - 0.016 14.0 0.0 0.038 12.8 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase IMUP PF15761.5 ORY89745.1 - 1.3 9.8 4.3 3 8.6 4.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein FAD-oxidase_C PF02913.19 ORY89746.1 - 3.3e-56 190.7 0.0 4.7e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY89746.1 - 9.1e-28 96.7 0.1 1.3e-17 63.9 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain zf-MYND PF01753.18 ORY89747.1 - 1.9e-05 24.6 11.2 3.4e-05 23.8 11.2 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY89747.1 - 0.2 12.0 9.8 0.34 11.2 9.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding XFP_N PF09364.10 ORY89749.1 - 1.7e-128 428.5 0.0 2.5e-128 427.9 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 ORY89749.1 - 5.3e-75 251.0 0.0 7.6e-75 250.5 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 ORY89749.1 - 2.3e-61 206.8 0.0 3.5e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain AFOR_N PF02730.15 ORY89749.1 - 0.021 14.7 0.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Acetate_kinase PF00871.17 ORY89750.1 - 4.8e-67 226.3 0.0 6.6e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Acetokinase family IF-2B PF01008.17 ORY89752.1 - 1.1e-48 165.8 0.0 1.4e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family L_lactis_ph-MCP PF06673.11 ORY89752.1 - 0.0053 15.8 0.0 0.0077 15.3 0.0 1.1 1 0 0 1 1 1 1 Lactococcus lactis bacteriophage major capsid protein Vps8 PF12816.7 ORY89753.1 - 1.4e-66 223.8 0.0 1.5e-65 220.5 0.0 2.7 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 ORY89753.1 - 5e-07 29.7 0.5 0.018 14.9 0.0 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS Toprim_2 PF13155.6 ORY89753.1 - 0.077 13.4 0.1 2.2 8.8 0.0 2.7 2 0 0 2 2 2 0 Toprim-like CBM_20 PF00686.19 ORY89754.1 - 2.6e-23 81.8 1.4 5.9e-23 80.6 1.4 1.6 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.24 ORY89754.1 - 2.8e-12 46.9 0.0 3.1e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain SecY PF00344.20 ORY89755.1 - 1.8e-69 234.3 9.7 2.3e-69 234.0 9.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORY89755.1 - 6.2e-19 67.5 1.6 1.1e-18 66.8 0.1 2.2 2 0 0 2 2 2 1 Plug domain of Sec61p DUF3817 PF12823.7 ORY89755.1 - 0.089 13.6 0.4 7.9 7.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) RseC_MucC PF04246.12 ORY89755.1 - 0.64 10.0 2.6 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2975 PF11188.8 ORY89755.1 - 3.3 7.6 7.2 1.6 8.6 2.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Vps53_N PF04100.12 ORY89757.1 - 4.7e-82 276.0 0.0 8.1e-82 275.2 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 ORY89757.1 - 0.00046 20.1 0.2 0.0051 16.7 0.0 2.5 2 1 1 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus MIS13 PF08202.11 ORY89757.1 - 0.049 12.9 0.1 0.079 12.2 0.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family SBF_like PF13593.6 ORY89758.1 - 2.5e-89 299.7 10.7 2.9e-89 299.5 10.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 ORY89758.1 - 5e-12 45.9 2.9 1.2e-11 44.7 2.9 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family KdgT PF03812.13 ORY89758.1 - 0.019 14.3 5.6 0.042 13.2 0.1 2.3 2 0 0 2 2 2 0 2-keto-3-deoxygluconate permease SPX PF03105.19 ORY89759.1 - 3 7.7 7.2 5.1 6.9 7.2 1.5 1 0 0 1 1 1 0 SPX domain bZIP_1 PF00170.21 ORY89760.1 - 1.4e-07 31.5 9.0 3.3e-05 23.9 9.0 2.4 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY89760.1 - 2.1e-06 27.7 7.2 1.3e-05 25.1 6.0 2.3 1 1 1 2 2 2 1 Basic region leucine zipper SlyX PF04102.12 ORY89760.1 - 0.0017 18.9 0.1 0.048 14.3 0.1 2.6 2 0 0 2 2 2 1 SlyX bZIP_Maf PF03131.17 ORY89760.1 - 0.0071 16.8 3.0 0.023 15.2 2.9 1.9 2 0 0 2 2 1 1 bZIP Maf transcription factor TolA_bind_tri PF16331.5 ORY89760.1 - 0.0088 16.1 1.0 0.022 14.8 1.0 1.6 1 0 0 1 1 1 1 TolA binding protein trimerisation Rootletin PF15035.6 ORY89760.1 - 0.031 14.3 1.2 0.053 13.5 1.2 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMF_DNA_bd PF12329.8 ORY89760.1 - 0.059 13.4 0.2 0.059 13.4 0.2 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 ORY89760.1 - 0.071 12.0 2.3 0.1 11.5 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.11 ORY89760.1 - 0.09 11.6 1.2 0.15 10.9 1.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CREPT PF16566.5 ORY89760.1 - 0.11 12.7 0.4 0.28 11.4 0.4 1.7 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour RAC_head PF16717.5 ORY89760.1 - 0.11 13.5 0.9 0.23 12.5 0.9 1.5 1 0 0 1 1 1 0 Ribosome-associated complex head domain YabA PF06156.13 ORY89760.1 - 0.12 13.0 0.5 0.24 12.0 0.5 1.4 1 0 0 1 1 1 0 Initiation control protein YabA Macoilin PF09726.9 ORY89760.1 - 0.16 10.5 7.0 0.23 10.0 7.0 1.1 1 0 0 1 1 1 0 Macoilin family FlaC_arch PF05377.11 ORY89760.1 - 0.32 11.4 1.4 0.65 10.4 1.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CASP_C PF08172.12 ORY89760.1 - 3.6 6.8 11.7 1.8 7.9 8.0 2.2 2 1 0 2 2 2 0 CASP C terminal Peptidase_M43 PF05572.13 ORY89761.1 - 7.1e-18 65.0 0.1 1.4e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 ORY89761.1 - 3.5e-07 30.8 0.1 5.7e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY89761.1 - 5.4e-07 30.0 0.3 7.8e-07 29.4 0.3 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 ORY89761.1 - 0.014 15.0 0.6 0.014 15.0 0.6 2.2 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 ORY89761.1 - 0.015 15.4 1.1 0.015 15.4 1.1 1.9 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M10 PF00413.24 ORY89761.1 - 0.021 14.7 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 ORY89761.1 - 0.048 12.9 0.2 0.078 12.2 0.2 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 ORY89761.1 - 0.063 12.2 1.0 0.11 11.4 1.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_2 PF13574.6 ORY89761.1 - 0.072 13.0 0.2 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Spermine_synth PF01564.17 ORY89762.1 - 4e-09 36.1 0.0 6.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 ORY89762.1 - 0.002 18.8 0.0 0.0059 17.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY89762.1 - 0.0033 18.0 0.0 0.0096 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY89762.1 - 0.13 13.1 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Beta-lactamase PF00144.24 ORY89764.1 - 9.2e-26 90.9 0.1 1.5e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF21 PF01595.20 ORY89765.1 - 6e-33 114.0 0.1 1.1e-32 113.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORY89765.1 - 0.0016 18.9 0.5 0.092 13.2 0.0 3.3 3 0 0 3 3 3 1 CBS domain Acyltransferase PF01553.21 ORY89766.1 - 3.9e-20 71.8 0.0 7.2e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Suc_Fer-like PF06999.12 ORY89767.1 - 1.3e-31 110.0 0.0 1.7e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.27 ORY89767.1 - 3.8e-07 30.0 1.0 2.4e-06 27.4 1.0 2.2 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_1 PF00667.20 ORY89768.1 - 2.8e-60 203.7 0.0 7e-60 202.4 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY89768.1 - 9.5e-35 119.9 0.3 2.4e-34 118.6 0.1 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ORY89768.1 - 3.1e-20 72.8 0.0 3.5e-19 69.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain BSD PF03909.17 ORY89771.1 - 2.1e-17 62.9 1.5 2e-12 46.9 0.1 2.4 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 ORY89771.1 - 2.2e-13 50.3 0.0 5.3e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Cyclin_C_2 PF16899.5 ORY89772.1 - 1e-17 64.4 1.5 1.1e-14 54.7 0.4 2.4 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 ORY89772.1 - 6.6e-10 38.8 0.7 1.3e-09 37.9 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY89772.1 - 0.00021 21.3 0.0 0.00053 20.0 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat DASH_Dad1 PF08649.10 ORY89773.1 - 8.1e-25 86.8 0.3 1e-24 86.5 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 ORY89773.1 - 0.00036 20.5 0.0 0.00052 19.9 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 Elf4 PF07011.11 ORY89773.1 - 0.077 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Early Flowering 4 domain WD40 PF00400.32 ORY89774.1 - 1.2e-23 83.0 10.4 0.00012 22.8 0.0 7.0 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY89774.1 - 2.2e-18 66.3 0.5 3.6e-06 27.2 0.1 4.4 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY89774.1 - 2.8e-05 24.1 0.4 0.00032 20.6 0.3 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 ORY89774.1 - 0.019 13.6 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 ORY89774.1 - 0.042 12.5 0.0 0.071 11.7 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Spermine_synth PF01564.17 ORY89775.1 - 2.1e-10 40.3 0.0 3.3e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 ORY89775.1 - 0.0013 19.4 0.0 0.0034 18.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY89775.1 - 0.048 14.3 0.0 0.39 11.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.19 ORY89776.1 - 6.9e-35 120.5 0.0 1.8e-28 99.3 0.0 2.0 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY89776.1 - 5.2e-15 55.5 0.0 1.8e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY89776.1 - 5.6e-15 55.4 0.0 2.7e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY89776.1 - 5.2e-10 39.4 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY89776.1 - 2.5e-09 37.6 2.6 0.0003 21.3 0.2 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY89776.1 - 3e-07 29.9 0.2 1e-05 24.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY89776.1 - 9.5e-06 25.4 0.2 0.015 14.9 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY89776.1 - 1.6e-05 25.0 2.2 0.0019 18.2 0.0 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ORY89776.1 - 3.6e-05 24.2 0.0 0.44 11.0 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding Amino_oxidase PF01593.24 ORY89776.1 - 4e-05 23.1 0.0 0.00013 21.4 0.0 1.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORY89776.1 - 0.00026 20.4 4.1 0.088 12.1 0.1 3.3 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY89776.1 - 0.00082 18.6 0.1 0.037 13.1 0.1 2.4 1 1 1 2 2 2 1 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY89776.1 - 0.0023 17.6 0.1 0.0039 16.8 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 ORY89776.1 - 0.011 14.5 0.2 0.077 11.7 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 ORY89776.1 - 0.011 14.9 0.1 0.43 9.8 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 ORY89776.1 - 0.022 14.8 0.2 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ORY89776.1 - 0.027 13.7 0.1 0.061 12.6 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain IlvN PF07991.12 ORY89776.1 - 0.084 12.4 0.1 15 5.1 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 ORY89776.1 - 0.12 11.8 0.2 13 5.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sugar_tr PF00083.24 ORY89777.1 - 2.9e-97 326.4 20.0 3.3e-97 326.2 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY89777.1 - 1.9e-06 27.1 42.1 1.2e-05 24.5 9.2 3.1 2 2 2 4 4 4 4 Major Facilitator Superfamily MFS_2 PF13347.6 ORY89777.1 - 2e-05 23.3 2.1 2e-05 23.3 2.1 2.7 2 1 0 2 2 2 1 MFS/sugar transport protein Phage_holin_3_2 PF04550.12 ORY89777.1 - 0.17 12.5 2.7 2.1 8.9 0.4 2.5 2 0 0 2 2 2 0 Phage holin family 2 F-box-like PF12937.7 ORY89778.1 - 0.0002 21.2 0.7 0.0031 17.4 0.1 3.1 2 0 0 2 2 2 1 F-box-like MARVEL PF01284.23 ORY89780.1 - 0.00078 19.5 11.5 0.0011 19.0 11.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain KASH PF10541.9 ORY89780.1 - 2.4 8.5 10.6 3.4 8.0 0.4 3.3 2 1 1 3 3 3 0 Nuclear envelope localisation domain PRP3 PF08572.10 ORY89782.1 - 3.6e-69 232.9 6.6 7.1e-69 232.0 6.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 ORY89782.1 - 1.1e-38 132.6 0.0 2.8e-38 131.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RCC1 PF00415.18 ORY89783.1 - 7.9e-18 64.8 4.8 1.5e-05 25.5 3.4 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY89783.1 - 6.5e-13 48.1 14.8 0.00031 20.4 0.1 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 ORY89783.1 - 0.74 9.9 3.7 3.5 7.7 0.3 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain tRNA-synt_1 PF00133.22 ORY89786.1 - 2.1e-220 733.1 0.1 2.7e-220 732.7 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY89786.1 - 9.8e-24 84.0 0.0 2.2e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY89786.1 - 3.9e-14 52.2 0.2 0.00073 18.4 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 ORY89786.1 - 0.0014 18.0 0.0 0.0038 16.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Methyltransf_3 PF01596.17 ORY89787.1 - 1.6e-33 115.7 0.0 2.3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 ORY89787.1 - 6.8e-10 39.9 0.0 3.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY89787.1 - 0.0044 16.7 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 zf-C2H2_jaz PF12171.8 ORY89788.1 - 2e-05 24.7 0.8 3.1e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY89788.1 - 6.6e-05 23.2 0.2 0.00015 22.0 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 ORY89788.1 - 0.043 13.9 2.6 0.18 11.9 2.6 2.1 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2_4 PF13894.6 ORY89788.1 - 0.063 14.1 0.1 0.13 13.2 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY89788.1 - 0.093 13.2 0.7 0.19 12.3 0.7 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 ORY89788.1 - 0.17 12.0 0.1 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 DBF zinc finger RNA_pol_Rpc4 PF05132.14 ORY89788.1 - 8.8 6.7 11.1 7.1 7.1 1.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF4660 PF15559.6 ORY89788.1 - 9.5 6.6 14.1 0.058 13.7 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4660) Ribosomal_S5 PF00333.20 ORY89789.1 - 9.5e-29 99.2 2.2 1.3e-28 98.8 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORY89789.1 - 1.1e-22 79.2 0.0 1.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Metallophos PF00149.28 ORY89790.1 - 6.3e-36 124.8 0.1 1.2e-35 123.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF771 PF05595.11 ORY89790.1 - 0.1 12.6 0.1 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF771) Phe_tRNA-synt_N PF02912.18 ORY89790.1 - 0.15 12.0 0.1 0.57 10.2 0.0 1.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain F-box-like PF12937.7 ORY89791.1 - 1.7e-07 31.0 2.8 2.5e-07 30.5 0.2 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY89791.1 - 0.00033 20.4 0.2 0.0024 17.7 0.2 2.5 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 ORY89792.1 - 1.9e-13 50.0 12.2 5.4e-10 38.9 7.7 3.5 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY89792.1 - 7.9e-11 42.0 15.4 5.3e-05 23.5 1.9 5.1 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY89792.1 - 0.016 15.7 11.6 3.9 8.4 0.2 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 ORY89792.1 - 0.2 11.1 0.7 0.88 9.0 0.4 1.9 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 ORY89792.1 - 8.9 6.7 16.9 7.4 6.9 1.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Tim17 PF02466.19 ORY89794.1 - 3.8e-31 107.7 4.7 4.9e-31 107.4 4.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LRR_8 PF13855.6 ORY89795.1 - 1.3e-45 152.9 57.1 1.1e-14 53.9 3.0 9.0 6 3 4 10 10 10 8 Leucine rich repeat PP2C PF00481.21 ORY89795.1 - 5.5e-42 144.2 0.0 9.2e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 ORY89795.1 - 2.8e-37 126.1 58.9 2.2e-06 27.9 1.2 12.0 10 1 2 12 12 12 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 ORY89795.1 - 1.3e-25 90.1 0.0 2.7e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RA PF00788.23 ORY89795.1 - 2.2e-05 25.0 0.0 5.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_9 PF14580.6 ORY89795.1 - 0.00074 19.1 18.5 0.12 11.9 0.4 4.8 3 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 ORY89795.1 - 0.001 19.3 45.5 0.19 12.4 0.1 13.0 14 0 0 14 14 14 2 Leucine Rich Repeat LRR_5 PF13306.6 ORY89795.1 - 0.0013 18.7 0.5 2.9 7.9 0.0 2.9 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Ad_cyc_g-alpha PF08509.11 ORY89795.1 - 0.0019 17.9 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain MARVEL PF01284.23 ORY89797.1 - 0.0037 17.3 12.2 0.0055 16.7 12.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain KASH PF10541.9 ORY89797.1 - 6.9 7.0 11.6 5.9 7.2 0.6 3.3 2 1 1 3 3 3 0 Nuclear envelope localisation domain F-box-like PF12937.7 ORY89798.1 - 0.0011 18.9 1.0 0.011 15.6 0.1 3.0 2 0 0 2 2 2 1 F-box-like BRE1 PF08647.11 ORY89799.1 - 2.5e-22 78.8 1.0 2.5e-22 78.8 1.0 7.5 5 2 2 7 7 7 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.6 ORY89799.1 - 4.4e-08 32.8 7.8 9e-08 31.8 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY89799.1 - 7.8e-08 32.1 7.2 1.4e-07 31.3 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY89799.1 - 1.4e-06 28.1 8.7 2.8e-06 27.2 8.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY89799.1 - 1.8e-06 27.7 5.4 3.3e-06 26.9 5.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 ORY89799.1 - 8.1e-06 25.6 8.6 1.5e-05 24.7 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY89799.1 - 1.5e-05 25.2 7.3 2.9e-05 24.3 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY89799.1 - 4.1e-05 23.5 5.2 4.1e-05 23.5 5.2 1.9 2 0 0 2 2 1 1 RING-type zinc-finger MCC-bdg_PDZ PF10506.9 ORY89799.1 - 0.0025 17.8 1.7 0.0025 17.8 1.7 6.1 6 0 0 6 6 6 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Zn_ribbon_17 PF17120.5 ORY89799.1 - 0.0029 17.2 3.4 0.0051 16.4 3.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type TPR_MLP1_2 PF07926.12 ORY89799.1 - 0.013 15.5 2.0 0.013 15.5 2.0 8.0 5 2 3 8 8 6 0 TPR/MLP1/MLP2-like protein zf-RING_6 PF14835.6 ORY89799.1 - 0.014 15.3 4.2 0.03 14.2 4.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY89799.1 - 0.015 15.5 3.8 0.015 15.5 3.8 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-UDP PF14569.6 ORY89799.1 - 0.029 14.5 1.8 0.074 13.2 1.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Yop-YscD_ppl PF16693.5 ORY89799.1 - 0.054 12.9 3.8 0.083 12.3 0.0 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain BLOC1_2 PF10046.9 ORY89799.1 - 0.068 13.5 0.4 0.068 13.5 0.4 6.7 5 2 3 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Zn_Tnp_IS91 PF14319.6 ORY89799.1 - 0.11 12.5 3.9 0.42 10.7 3.9 2.0 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C3HC4_4 PF15227.6 ORY89799.1 - 0.13 12.5 7.1 0.27 11.4 7.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY89799.1 - 0.82 9.5 5.9 1.6 8.6 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 ORY89799.1 - 0.87 9.5 3.1 2.1 8.3 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 ORY89799.1 - 1.2 9.2 5.3 2.8 8.0 5.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 ORY89799.1 - 4.5 7.5 9.4 36 4.6 9.4 2.3 1 1 0 1 1 1 0 FYVE zinc finger ArfGap PF01412.18 ORY89800.1 - 2e-42 144.0 0.6 3.2e-42 143.3 0.6 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ATP-sulfurylase PF01747.17 ORY89801.1 - 4.6e-89 297.5 0.0 6.6e-89 297.0 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 ORY89801.1 - 2.3e-51 173.8 0.0 3.4e-51 173.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 ORY89801.1 - 1.1e-50 171.4 0.0 1.9e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain DUF4038 PF13204.6 ORY89802.1 - 5.5e-80 269.3 0.0 7.4e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 ORY89802.1 - 6.7e-18 64.5 0.0 1.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase Sugar_tr PF00083.24 ORY89803.1 - 5.7e-91 305.6 20.2 6.9e-91 305.4 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY89803.1 - 1.3e-09 37.5 61.1 1.5e-08 34.0 37.0 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY89803.1 - 0.0014 17.2 5.0 0.0014 17.2 5.0 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein GerA PF03323.13 ORY89803.1 - 3.6 6.0 4.8 5.9 5.2 4.8 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein F-box-like PF12937.7 ORY89804.1 - 0.00049 19.9 2.1 0.003 17.4 0.1 3.2 3 0 0 3 3 3 1 F-box-like zf-TRAF PF02176.18 ORY89805.1 - 2e-09 38.0 12.3 2.9e-08 34.3 3.9 3.2 2 1 1 3 3 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 ORY89805.1 - 2e-06 27.5 7.0 2e-06 27.5 7.0 3.4 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY89805.1 - 5.1e-06 26.3 4.2 5.1e-06 26.3 4.2 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY89805.1 - 1.8e-05 25.0 6.6 1.8e-05 25.0 6.6 3.4 2 1 1 3 3 1 1 Ring finger domain zf-TRAF_2 PF15965.5 ORY89805.1 - 0.00022 21.6 7.5 0.00022 21.6 7.5 2.8 2 1 0 2 2 2 1 TRAF-like zinc-finger zf-RING_5 PF14634.6 ORY89805.1 - 0.00037 20.4 4.6 0.00037 20.4 4.6 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY89805.1 - 0.00039 20.2 7.2 0.00039 20.2 7.2 3.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORY89805.1 - 0.0011 19.1 2.9 0.0011 19.1 2.9 2.0 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 ORY89805.1 - 0.0075 16.3 7.5 0.0075 16.3 7.5 2.4 2 1 0 2 2 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 ORY89805.1 - 0.013 15.4 1.5 0.013 15.4 1.5 2.2 2 1 0 2 2 1 0 zf-RING of BARD1-type protein Vac_Fusion PF02346.16 ORY89805.1 - 0.085 12.5 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Sina PF03145.16 ORY89805.1 - 0.32 10.9 11.6 4.6 7.1 0.8 3.2 2 1 1 3 3 3 0 Seven in absentia protein family DM PF00751.18 ORY89805.1 - 0.33 10.9 3.4 0.27 11.2 1.0 2.1 2 0 0 2 2 2 0 DM DNA binding domain GAGA PF09237.11 ORY89805.1 - 7.3 6.5 6.8 0.46 10.3 0.5 2.3 3 0 0 3 3 3 0 GAGA factor Transketolase_N PF00456.21 ORY89806.1 - 1e-122 409.3 0.0 1.4e-122 408.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY89806.1 - 2.9e-39 134.6 0.1 7.3e-39 133.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY89806.1 - 1.3e-10 41.2 0.0 5.6e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 ORY89806.1 - 0.002 18.0 0.0 0.01 15.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORY89806.1 - 0.022 14.0 0.0 0.071 12.3 0.0 1.7 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase UDPG_MGDP_dh_N PF03721.14 ORY89806.1 - 0.17 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldo_ket_red PF00248.21 ORY89807.1 - 1.2e-51 175.7 0.2 1.8e-50 171.8 0.2 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Rib_5-P_isom_A PF06026.14 ORY89809.1 - 4.9e-60 202.1 0.0 6.7e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 ORY89809.1 - 0.022 14.7 0.0 1.2 9.1 0.0 2.2 1 1 0 2 2 2 0 DeoR C terminal sensor domain Gemini_AC4_5 PF04807.12 ORY89809.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region PheRS_DBD2 PF18554.1 ORY89809.1 - 0.069 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 PheRS DNA binding domain 2 p450 PF00067.22 ORY89810.1 - 5.9e-76 256.1 0.0 7.3e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M48 PF01435.18 ORY89811.1 - 8.2e-27 94.2 0.0 1.3e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 ADH_N PF08240.12 ORY89812.1 - 5.6e-29 100.2 1.6 5.6e-29 100.2 1.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY89812.1 - 3.5e-20 72.3 0.0 5.2e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY89812.1 - 0.00024 20.7 0.9 0.004 16.7 0.9 2.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORY89812.1 - 0.00041 19.7 0.1 0.00067 19.0 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY89812.1 - 0.0027 16.9 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY89812.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY89812.1 - 0.028 13.7 0.0 0.077 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.21 ORY89812.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DAO PF01266.24 ORY89812.1 - 0.096 12.3 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY89812.1 - 0.1 11.9 0.3 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY89812.1 - 0.14 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.18 ORY89813.1 - 6.3e-29 100.8 0.0 2.4e-28 98.9 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY89813.1 - 2.5e-07 30.7 7.4 4.1e-07 30.0 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Antimicrobial_9 PF08104.11 ORY89814.1 - 0.17 11.9 0.9 0.27 11.3 0.9 1.3 1 0 0 1 1 1 0 Ponericin L family Peptidase_C54 PF03416.19 ORY89815.1 - 4.6e-82 275.5 0.0 9.4e-61 205.6 0.0 2.1 1 1 1 2 2 2 2 Peptidase family C54 Arf PF00025.21 ORY89816.1 - 1.6e-75 252.4 0.1 1.8e-75 252.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY89816.1 - 1.5e-15 57.5 0.1 1.9e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY89816.1 - 1.3e-13 50.9 0.0 1.5e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY89816.1 - 2.2e-12 46.8 1.4 5.8e-08 32.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY89816.1 - 6.5e-12 45.2 0.0 8.3e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY89816.1 - 4e-10 39.4 0.0 5.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY89816.1 - 6.4e-05 23.0 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY89816.1 - 0.002 17.5 0.2 0.0025 17.1 0.2 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase API5 PF05918.11 ORY89817.1 - 0.0033 16.3 0.0 16 4.2 0.0 3.0 3 0 0 3 3 3 3 Apoptosis inhibitory protein 5 (API5) Antimicrobial_9 PF08104.11 ORY89817.1 - 0.22 11.6 0.9 0.37 10.8 0.9 1.3 1 0 0 1 1 1 0 Ponericin L family Sugar_tr PF00083.24 ORY89818.1 - 7e-77 259.2 17.5 8.5e-77 258.9 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY89818.1 - 1.2e-15 57.3 42.5 1.9e-15 56.7 36.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY89818.1 - 0.00045 19.2 4.0 0.00045 19.2 4.0 2.4 1 1 1 2 2 2 1 MFS_1 like family TRI12 PF06609.13 ORY89818.1 - 0.00051 18.6 0.8 0.00051 18.6 0.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF697 PF05128.12 ORY89818.1 - 0.012 15.3 0.6 0.027 14.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF697) DUF4038 PF13204.6 ORY89819.1 - 6.8e-81 272.3 0.0 8.7e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Collagen_bind_2 PF12904.7 ORY89819.1 - 4.2e-09 36.3 0.0 7.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Putative collagen-binding domain of a collagenase RTA1 PF04479.13 ORY89820.1 - 1.1e-40 139.5 11.7 1.8e-40 138.8 11.7 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2518 PF10726.9 ORY89820.1 - 0.2 11.3 3.6 0.47 10.1 3.6 1.6 1 0 0 1 1 1 0 Protein of function (DUF2518) YhhN PF07947.14 ORY89820.1 - 2.4 7.7 22.6 0.092 12.4 13.2 2.3 2 0 0 2 2 2 0 YhhN family UPF0139 PF03669.13 ORY89821.1 - 9.7e-07 28.6 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Humanin PF15040.6 ORY89821.1 - 1.9 8.0 4.0 0.4 10.2 0.4 1.7 2 0 0 2 2 2 0 Humanin family PTPA PF03095.15 ORY89822.1 - 5.9e-119 397.0 0.0 6.9e-119 396.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein NRho PF16733.5 ORY89822.1 - 0.046 13.8 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Rhomboid N-terminal domain TPR_1 PF00515.28 ORY89823.1 - 1.1e-23 82.0 1.0 5.4e-05 22.8 0.1 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY89823.1 - 1.1e-17 63.5 6.8 3.7e-05 23.3 0.2 5.4 2 2 3 5 5 5 4 TPR repeat TPR_2 PF07719.17 ORY89823.1 - 3.3e-16 58.0 4.9 0.00038 20.4 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY89823.1 - 4.2e-16 57.7 3.2 0.0016 18.5 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY89823.1 - 4.5e-15 54.9 5.7 6e-05 23.2 0.2 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY89823.1 - 5.4e-13 49.0 3.4 5.9e-05 23.3 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY89823.1 - 4.8e-11 42.5 14.6 0.0082 16.9 0.1 6.8 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY89823.1 - 6.1e-10 39.6 13.9 6.2e-06 26.8 0.1 5.1 4 2 3 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY89823.1 - 6.1e-10 39.5 9.2 1.7e-05 25.2 0.8 4.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY89823.1 - 1.6e-07 30.9 8.0 0.18 11.9 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY89823.1 - 1.6e-07 31.4 1.3 0.0016 18.6 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY89823.1 - 1.9e-06 28.1 5.3 0.0097 16.2 0.1 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY89823.1 - 0.0067 16.5 0.1 0.064 13.3 0.1 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 ORY89823.1 - 0.0071 16.5 1.1 0.052 13.8 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 ABC1 PF03109.16 ORY89823.1 - 0.097 12.8 1.1 0.19 11.9 0.1 2.1 2 0 0 2 2 1 0 ABC1 family TPR_10 PF13374.6 ORY89823.1 - 0.26 11.2 10.0 0.48 10.4 0.1 4.0 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY89823.1 - 0.53 11.0 9.5 4.9 8.0 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ODC_AZ PF02100.17 ORY89824.1 - 1.8e-09 37.6 0.0 3.9e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme SCAPER_N PF16501.5 ORY89824.1 - 0.092 12.8 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum Retinal PF15449.6 ORY89824.1 - 0.91 7.2 20.0 0.99 7.1 20.0 1.0 1 0 0 1 1 1 0 Retinal protein tRNA-synt_2d PF01409.20 ORY89825.1 - 3.3e-44 151.2 0.2 2.1e-24 86.4 0.0 2.2 1 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 ORY89825.1 - 3e-26 91.7 0.0 6.4e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain PAS PF00989.25 ORY89826.1 - 3.7e-07 30.1 0.0 6.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 ORY89826.1 - 0.012 15.7 14.5 0.024 14.8 14.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PRA1 PF03208.19 ORY89827.1 - 1.2e-33 115.7 1.0 1.5e-33 115.4 1.0 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2868 PF11067.8 ORY89827.1 - 5.9 6.3 7.2 8.3 5.8 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PAC4 PF16093.5 ORY89828.1 - 4.1e-13 49.3 0.3 5.7e-13 48.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 RNA_pol_Rpc34 PF05158.12 ORY89829.1 - 1.2e-65 222.1 6.6 1.1e-61 209.2 4.9 3.1 2 1 0 2 2 2 2 RNA polymerase Rpc34 subunit TrmB PF01978.19 ORY89829.1 - 0.0021 17.9 1.1 0.13 12.2 0.0 3.4 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 ORY89829.1 - 0.027 14.2 0.2 0.56 10.0 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain Macoilin PF09726.9 ORY89829.1 - 0.24 9.9 8.1 0.31 9.6 8.1 1.1 1 0 0 1 1 1 0 Macoilin family Cnd1_N PF12922.7 ORY89829.1 - 0.33 10.8 0.0 0.33 10.8 0.0 4.0 3 2 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1, N-term Apt1 PF10351.9 ORY89829.1 - 8.6 5.1 10.7 14 4.4 10.7 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf-C2H2 PF00096.26 ORY89831.1 - 8.4e-10 38.6 7.5 4.6e-05 23.6 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY89831.1 - 4e-06 27.0 9.7 0.00012 22.3 1.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY89831.1 - 6.8e-05 23.4 6.3 0.021 15.6 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY89831.1 - 0.022 14.8 2.8 0.054 13.5 1.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY89831.1 - 0.024 15.0 0.7 0.067 13.5 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc ribbon FRQ PF09421.10 ORY89832.1 - 1e-26 93.3 12.6 1.2e-17 63.3 0.6 3.5 3 0 0 3 3 3 2 Frequency clock protein FtsJ PF01728.19 ORY89833.1 - 4.2e-40 137.7 0.0 5.5e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase CAP59_mtransfer PF11735.8 ORY89834.1 - 1.9e-63 214.4 0.0 2.4e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_4 PF13704.6 ORY89834.1 - 0.15 12.6 0.1 0.43 11.1 0.1 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 IF4E PF01652.18 ORY89835.1 - 5.8e-36 123.7 0.0 3.1e-35 121.3 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic initiation factor 4E ACBP PF00887.19 ORY89836.1 - 1.1e-16 60.8 0.2 3e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Ank_2 PF12796.7 ORY89836.1 - 8.6e-10 39.1 0.1 1.2e-09 38.6 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY89836.1 - 1.6e-09 37.8 0.1 1.6e-08 34.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY89836.1 - 5.3e-09 36.1 0.9 8.8e-05 22.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORY89836.1 - 1.1e-08 35.4 0.1 0.00019 22.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY89836.1 - 0.00087 19.6 0.0 0.18 12.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Alliinase_C PF04864.13 ORY89836.1 - 0.077 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Allinase G-alpha PF00503.20 ORY89837.1 - 6.2e-119 397.3 1.9 7.5e-119 397.0 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY89837.1 - 2.7e-17 62.8 0.7 8.4e-12 44.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY89837.1 - 0.00011 21.7 0.4 0.023 14.1 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 ORY89837.1 - 0.0017 18.2 0.1 0.0086 15.9 0.0 2.1 2 0 0 2 2 2 1 CHC2 zinc finger Roc PF08477.13 ORY89837.1 - 0.0022 18.2 0.9 1.2 9.3 0.0 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY89837.1 - 0.011 15.8 0.0 2.8 8.1 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase MCM PF00493.23 ORY89837.1 - 0.012 14.7 0.1 0.023 13.8 0.1 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 ORY89837.1 - 0.014 15.2 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 ORY89837.1 - 0.14 11.6 0.1 4.6 6.7 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 ORY89838.1 - 7.6e-45 150.0 15.2 5.9e-10 39.6 0.2 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 ORY89838.1 - 3e-27 95.4 0.0 8e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain Methyltransf_7 PF03492.15 ORY89838.1 - 4.7e-11 42.5 0.7 1.2e-06 28.0 3.0 2.5 3 0 0 3 3 3 2 SAM dependent carboxyl methyltransferase ANAPC4_WD40 PF12894.7 ORY89838.1 - 4e-10 39.9 0.1 0.013 15.7 0.0 5.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY89838.1 - 0.00014 20.7 1.1 1.4 7.5 0.0 4.0 3 2 1 4 4 4 2 Nucleoporin Nup120/160 LisH PF08513.11 ORY89838.1 - 0.047 13.7 0.3 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 LisH Ge1_WD40 PF16529.5 ORY89838.1 - 0.064 12.2 0.1 18 4.2 0.0 3.4 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ELYS-bb PF16687.5 ORY89838.1 - 0.082 11.5 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin WD40_like PF17005.5 ORY89838.1 - 0.27 10.5 0.0 7.9 5.7 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain Slu7 PF11708.8 ORY89839.1 - 3.2e-104 348.4 13.6 3.2e-104 348.4 13.6 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 ORY89839.1 - 0.021 14.6 0.5 0.038 13.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4337 PF14235.6 ORY89839.1 - 0.36 10.9 1.8 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Vfa1 PF08432.10 ORY89839.1 - 7.1 6.9 19.6 0.71 10.2 2.3 2.6 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 MFS_1 PF07690.16 ORY89841.1 - 5e-33 114.5 29.6 5e-33 114.5 29.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 ORY89842.1 - 1.7e-53 181.7 0.0 2.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY89842.1 - 4e-28 98.4 0.0 5.4e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY89842.1 - 8.4e-05 22.0 0.1 0.00089 18.6 0.3 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY89842.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY89842.1 - 0.0065 16.4 0.0 0.0065 16.4 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY89842.1 - 0.037 13.0 0.0 0.045 12.7 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain HECT PF00632.25 ORY90057.1 - 4.5e-74 249.7 0.0 5e-74 249.5 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF5526 PF17664.1 ORY90057.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5526) ABC2_membrane PF01061.24 ORY90058.1 - 8.9e-80 267.0 57.2 6.5e-45 153.1 18.0 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY90058.1 - 2.6e-16 60.4 0.0 4.5e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.6 ORY90058.1 - 7.6e-15 55.3 0.3 1.5e-14 54.3 0.3 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal PDR_CDR PF06422.12 ORY90058.1 - 0.016 15.1 0.2 0.016 15.1 0.2 2.8 2 0 0 2 2 2 0 CDR ABC transporter DUF3093 PF11292.8 ORY90058.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) ABC2_membrane_3 PF12698.7 ORY90058.1 - 0.42 9.7 56.3 0.009 15.2 10.5 3.3 2 1 0 3 3 3 0 ABC-2 family transporter protein Aminotran_4 PF01063.19 ORY90059.1 - 8.7e-11 42.1 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DEAD PF00270.29 ORY90060.1 - 9.8e-45 152.5 0.0 2e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY90060.1 - 2.8e-27 95.3 0.0 5.5e-26 91.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 ORY90060.1 - 2.9e-05 23.0 0.1 0.00052 18.9 0.0 2.5 2 1 1 3 3 3 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ResIII PF04851.15 ORY90060.1 - 0.00018 21.6 0.0 0.00071 19.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cyclin PF08613.11 ORY90061.1 - 1.5e-19 70.9 0.0 3.4e-19 69.8 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY90061.1 - 0.0022 17.7 0.0 0.0099 15.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Mg_trans_NIPA PF05653.14 ORY90063.1 - 3.4e-87 292.3 14.8 4e-87 292.0 14.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY90063.1 - 0.0017 18.6 5.4 0.0017 18.6 5.4 3.9 3 1 0 3 3 3 1 EamA-like transporter family DUF3648 PF12364.8 ORY90063.1 - 0.084 13.1 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) AMP-binding PF00501.28 ORY90064.1 - 6.1e-71 239.2 0.0 8.4e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORY90064.1 - 8.8e-68 228.2 0.0 1.3e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ORY90064.1 - 1.9e-12 47.3 0.0 5.6e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 ORY90064.1 - 3.5e-12 45.8 0.0 6.2e-10 38.3 0.0 2.8 2 1 0 2 2 2 1 Condensation domain 3Beta_HSD PF01073.19 ORY90064.1 - 2.5e-07 30.0 0.0 5.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 ORY90064.1 - 5.7e-07 30.4 0.4 9.9e-05 23.2 0.4 3.0 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 ORY90064.1 - 3.8e-06 26.5 0.0 6.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-MYND PF01753.18 ORY90065.1 - 4.2e-08 33.1 14.6 7.4e-08 32.4 14.6 1.4 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.6 ORY90065.1 - 0.0074 16.6 0.1 0.015 15.6 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat F-box-like PF12937.7 ORY90069.1 - 6.7e-09 35.5 0.4 1.4e-08 34.4 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY90069.1 - 0.00025 20.8 1.2 0.00068 19.4 0.4 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 ORY90069.1 - 6.5 7.3 9.3 9.1 6.9 0.2 4.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Acetyltransf_1 PF00583.25 ORY90070.1 - 3e-09 37.1 0.0 3.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY90070.1 - 4.4e-08 33.4 0.0 6.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY90070.1 - 1.3e-07 31.6 0.0 1.6e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain K_oxygenase PF13434.6 ORY90071.1 - 5.4e-14 52.1 0.0 2.6e-07 30.1 0.0 3.2 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY90071.1 - 0.00011 21.6 0.0 0.0036 16.6 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY90071.1 - 0.0013 18.8 0.0 0.13 12.3 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 ORY90071.1 - 0.0058 16.3 2.5 4 6.9 0.0 3.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY90071.1 - 0.059 12.6 0.1 49 3.0 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY90071.1 - 0.21 11.8 1.0 3.2 8.0 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain zf-HC2 PF13490.6 ORY90072.1 - 3.1 8.1 5.3 0.39 11.0 0.6 2.1 2 0 0 2 2 2 0 Putative zinc-finger Ribosomal_S25 PF03297.15 ORY90074.1 - 1.9e-39 133.9 1.7 2.1e-39 133.8 1.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.6 ORY90074.1 - 0.017 14.7 0.3 0.029 13.9 0.3 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AIPR PF10592.9 ORY90074.1 - 0.071 12.7 0.1 0.071 12.7 0.1 1.1 1 0 0 1 1 1 0 AIPR protein HydF_dimer PF18128.1 ORY90074.1 - 0.079 13.0 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain Cytochrom_B558a PF05038.13 ORY90075.1 - 3.8 7.1 5.0 7.2 6.1 5.0 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Glyco_hydro_125 PF06824.11 ORY90076.1 - 1e-135 452.9 0.0 1.5e-135 452.3 0.0 1.3 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) DUF5018 PF16410.5 ORY90076.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5018) HpcH_HpaI PF03328.14 ORY90077.1 - 4.3e-32 111.0 0.0 5.5e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 ORY90077.1 - 0.029 13.5 1.8 0.77 8.8 0.4 3.0 3 1 0 3 3 3 0 PEP-utilising enzyme, TIM barrel domain baeRF_family11 PF18855.1 ORY90077.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 Sugar_tr PF00083.24 ORY90078.1 - 3.9e-83 279.8 23.6 4.6e-83 279.6 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY90078.1 - 3.5e-15 55.8 70.8 9.9e-14 51.0 40.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 ORY90079.1 - 8e-56 188.2 0.0 1.1e-55 187.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY90079.1 - 2.4e-22 79.0 0.0 2.8e-22 78.8 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY90079.1 - 2.7e-06 27.6 0.0 4.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ORY90079.1 - 0.0031 17.6 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 ORY90079.1 - 0.015 15.6 0.0 0.042 14.1 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 ORY90079.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 ORY90079.1 - 0.089 13.2 0.0 0.33 11.4 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Fungal_trans PF04082.18 ORY90080.1 - 2.7e-22 79.1 0.0 4.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY90080.1 - 6.3e-06 26.2 6.8 6.3e-06 26.2 6.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.12 ORY90081.1 - 1.2e-38 133.1 0.0 1.5e-38 132.8 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 ORY90081.1 - 1.9e-08 33.9 0.0 0.83 9.8 0.0 5.6 5 0 0 5 5 5 2 NHL repeat Arylesterase PF01731.20 ORY90081.1 - 1.3e-05 25.2 0.0 0.00011 22.3 0.0 2.5 4 0 0 4 4 4 1 Arylesterase Str_synth PF03088.16 ORY90081.1 - 0.00063 19.8 0.0 0.29 11.3 0.0 3.7 3 2 0 3 3 3 1 Strictosidine synthase Lactonase PF10282.9 ORY90081.1 - 0.0014 18.0 0.0 0.038 13.2 0.0 2.4 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller SdiA-regulated PF06977.11 ORY90081.1 - 0.25 10.5 0.0 20 4.3 0.0 2.3 2 0 0 2 2 2 0 SdiA-regulated DUF3584 PF12128.8 ORY90082.1 - 0.56 7.6 15.3 0.86 7.0 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Presenilin PF01080.17 ORY90082.1 - 5.9 5.5 4.8 8.9 5.0 4.8 1.3 1 0 0 1 1 1 0 Presenilin eIF2A PF08662.11 ORY90083.1 - 3.2e-82 275.1 0.0 1.9e-80 269.3 0.0 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 ORY90083.1 - 7.8e-05 22.9 0.0 0.27 11.6 0.0 4.1 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY90083.1 - 0.025 15.4 0.6 32 5.6 0.0 4.7 4 1 0 5 5 5 0 WD domain, G-beta repeat PD40 PF07676.12 ORY90083.1 - 0.08 12.9 2.0 20 5.3 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CDV3 PF15359.6 ORY90083.1 - 0.25 11.8 0.1 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Proteasome_A_N PF10584.9 ORY90083.1 - 0.92 9.3 4.3 93 2.8 0.1 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Cupin_2 PF07883.11 ORY90084.1 - 7e-09 35.3 0.1 2.7e-07 30.2 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Peptidase_S15 PF02129.18 ORY90085.1 - 3.7e-41 141.5 0.5 4.9e-41 141.1 0.5 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 ORY90085.1 - 5.4e-30 105.0 0.0 9.1e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 ORY90085.1 - 0.00057 19.2 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY90085.1 - 0.0049 16.4 0.1 0.0079 15.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FAD_binding_4 PF01565.23 ORY90086.1 - 1.1e-20 73.8 0.1 1.7e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short_C2 PF13561.6 ORY90087.1 - 5.2e-57 193.1 2.8 5.9e-57 192.9 2.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY90087.1 - 2.4e-44 151.1 1.6 3e-44 150.8 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY90087.1 - 0.016 15.1 2.7 0.041 13.8 2.7 1.9 1 1 0 1 1 1 0 KR domain 3HCDH_N PF02737.18 ORY90087.1 - 0.077 12.9 0.6 0.14 12.0 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ephrin_lbd PF01404.19 ORY90087.1 - 0.19 11.8 0.1 3.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Ephrin receptor ligand binding domain Histidinol_dh PF00815.20 ORY90088.1 - 6.6e-135 450.3 0.5 8e-135 450.0 0.5 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase FAD_binding_3 PF01494.19 ORY90089.1 - 1.2e-16 61.0 0.6 3.2e-16 59.5 0.6 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY90089.1 - 4.4e-06 26.1 2.5 0.0011 18.3 0.3 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY90089.1 - 1.9e-05 24.5 6.9 0.0002 21.1 1.8 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY90089.1 - 3.3e-05 24.0 0.5 0.00012 22.2 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY90089.1 - 0.0017 17.1 1.5 0.0075 15.0 0.7 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY90089.1 - 0.0023 17.1 2.4 0.0023 17.1 2.4 1.5 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY90089.1 - 0.0038 16.6 0.2 0.0073 15.6 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 ORY90089.1 - 0.0081 15.3 0.9 0.027 13.5 0.9 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORY90089.1 - 0.014 14.7 0.9 0.023 14.0 0.9 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY90089.1 - 0.035 13.3 0.1 0.053 12.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 ORY90089.1 - 0.064 12.3 1.0 0.11 11.5 1.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 ORY90089.1 - 0.097 12.9 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 ORY90089.1 - 0.098 11.5 2.9 0.059 12.2 0.8 1.6 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 ORY90089.1 - 0.14 11.5 0.7 0.23 10.8 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase LigB PF02900.18 ORY90090.1 - 4.1e-16 58.9 0.0 5.1e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase MFS_1 PF07690.16 ORY90091.1 - 2.8e-28 98.9 33.4 2.8e-28 98.9 33.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY90091.1 - 1e-15 57.6 9.7 1e-15 57.6 9.7 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter ATG22 PF11700.8 ORY90091.1 - 0.00053 18.7 9.2 0.00096 17.9 9.2 1.4 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like OATP PF03137.20 ORY90091.1 - 0.088 11.1 2.1 0.16 10.2 2.1 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Aldedh PF00171.22 ORY90092.1 - 1.1e-21 76.9 0.1 9.2e-21 73.9 0.1 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Nup188 PF10487.9 ORY90092.1 - 0.025 12.5 0.9 0.034 12.1 0.9 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 ATP-synt_A PF00119.20 ORY90092.1 - 0.039 13.9 0.1 0.07 13.1 0.1 1.4 1 0 0 1 1 1 0 ATP synthase A chain ADC PF06314.11 ORY90094.1 - 6.5e-17 61.9 0.0 9.4e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) adh_short PF00106.25 ORY90095.1 - 4.9e-53 179.5 0.2 6.1e-53 179.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY90095.1 - 5.6e-36 124.3 0.1 7.1e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY90095.1 - 7.8e-09 35.7 0.0 1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY90095.1 - 5.1e-08 32.6 0.0 1.8e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY90095.1 - 6e-05 22.6 0.0 7.9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY90095.1 - 0.0014 18.1 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Folliculin_C PF16692.5 ORY90095.1 - 0.2 11.3 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Folliculin C-terminal domain Fungal_trans PF04082.18 ORY90096.1 - 1.3e-15 57.1 0.1 2.6e-15 56.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase_C PF02806.18 ORY90097.1 - 1.3e-27 96.1 0.4 3.6e-27 94.7 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 ORY90097.1 - 1.6e-16 60.4 0.0 4e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ORY90097.1 - 3.3e-11 43.3 1.5 8e-10 38.8 0.2 2.8 2 1 1 3 3 3 1 Alpha amylase, catalytic domain GF_recep_IV PF14843.6 ORY90098.1 - 7.2e-05 22.6 40.8 0.00053 19.8 12.2 3.5 3 1 0 3 3 3 2 Growth factor receptor domain IV Furin-like PF00757.20 ORY90098.1 - 0.6 10.0 43.8 0.086 12.7 11.2 3.6 2 2 1 3 3 3 0 Furin-like cysteine rich region GPI-anchored PF10342.9 ORY90099.1 - 1.7e-06 28.7 0.3 1.7e-06 28.7 0.3 1.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family HYR PF02494.16 ORY90099.1 - 0.072 13.4 0.2 0.76 10.2 0.0 2.5 2 1 1 3 3 3 0 HYR domain MIF4G PF02854.19 ORY90100.1 - 1.5e-56 191.4 0.0 2.2e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain FANCI_S2 PF14676.6 ORY90100.1 - 0.066 13.5 0.0 2.9 8.2 0.0 2.3 2 0 0 2 2 2 0 FANCI solenoid 2 CPSF100_C PF13299.6 ORY90100.1 - 4.6 7.4 7.1 0.59 10.3 0.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RNase_T PF00929.24 ORY90101.1 - 1.1e-28 100.9 0.0 1.2e-28 100.7 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Abhydrolase_1 PF00561.20 ORY90101.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3584 PF12128.8 ORY90102.1 - 8.7e-07 26.9 23.5 8.7e-07 26.9 23.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) DUF5082 PF16888.5 ORY90102.1 - 0.014 15.7 15.6 0.073 13.4 0.4 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 ORY90102.1 - 0.047 13.9 18.7 0.094 12.9 10.6 3.5 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family DIT1_PvcA PF05141.12 ORY90102.1 - 0.28 10.6 7.9 0.68 9.3 7.9 1.6 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein ABC_tran_CTD PF16326.5 ORY90102.1 - 0.47 10.7 47.1 0.4 11.0 12.3 5.2 3 1 0 4 4 4 0 ABC transporter C-terminal domain DUF3818 PF12825.7 ORY90102.1 - 0.75 8.7 9.6 1.6 7.7 9.6 1.5 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Tropomyosin_1 PF12718.7 ORY90102.1 - 1.1 9.4 44.8 6.1 7.0 0.7 4.6 3 1 1 4 4 4 0 Tropomyosin like HAUS-augmin3 PF14932.6 ORY90102.1 - 1.5 8.3 35.0 0.058 13.0 9.3 3.5 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 COG2 PF06148.11 ORY90102.1 - 1.6 8.8 18.9 0.55 10.3 3.5 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HlyD_2 PF12700.7 ORY90102.1 - 1.8 7.2 5.3 3.2 6.4 5.3 1.3 1 0 0 1 1 1 0 HlyD family secretion protein GAGA_bind PF06217.12 ORY90102.1 - 4 7.6 6.1 12 6.1 6.1 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family Med9 PF07544.13 ORY90102.1 - 8 6.6 23.9 1.4 9.1 1.7 3.7 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.18 ORY90102.1 - 9.8 5.4 19.3 2.8 7.2 13.3 2.5 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein RVT_1 PF00078.27 ORY90103.1 - 0.00026 20.6 0.0 0.00049 19.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EzrA PF06160.12 ORY90105.1 - 0.0041 15.4 4.0 0.0057 14.9 4.0 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF4055 PF13264.6 ORY90105.1 - 0.0046 17.1 2.4 0.0083 16.3 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4055) APG6_N PF17675.1 ORY90105.1 - 0.81 10.2 17.5 0.13 12.8 9.8 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region PEP-utilisers_N PF05524.13 ORY90105.1 - 0.99 9.6 13.3 0.91 9.7 5.8 3.0 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal TMPIT PF07851.13 ORY90105.1 - 2.2 7.4 3.5 3.7 6.7 3.5 1.3 1 0 0 1 1 1 0 TMPIT-like protein Exonuc_VII_L PF02601.15 ORY90105.1 - 2.5 7.6 7.7 3.4 7.1 7.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF572 PF04502.13 ORY90105.1 - 2.8 7.5 12.7 3.7 7.1 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ATG16 PF08614.11 ORY90105.1 - 4.8 7.4 21.3 16 5.7 21.3 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 ORY90105.1 - 6.1 6.1 13.9 8.1 5.7 13.9 1.1 1 0 0 1 1 1 0 FAM76 protein BsuBI_PstI_RE_N PF17728.1 ORY90106.1 - 0.033 14.1 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain Lipoxygenase PF00305.19 ORY90106.1 - 0.12 10.8 0.2 0.17 10.2 0.2 1.2 1 0 0 1 1 1 0 Lipoxygenase Dioxygenase_C PF00775.21 ORY90108.1 - 2.2e-07 30.5 0.2 4.4e-06 26.2 0.2 2.2 1 1 0 1 1 1 1 Dioxygenase Pkinase PF00069.25 ORY90109.1 - 4.8e-69 232.6 0.0 6.3e-69 232.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90109.1 - 1.4e-36 126.1 0.0 1.9e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 ORY90109.1 - 0.01 15.5 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 FAM76 PF16046.5 ORY90109.1 - 0.058 12.8 4.0 0.087 12.2 4.0 1.1 1 0 0 1 1 1 0 FAM76 protein MAP65_ASE1 PF03999.12 ORY90109.1 - 6.1 5.4 7.9 8.1 5.0 7.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FSH1 PF03959.13 ORY90110.1 - 3.6e-55 186.9 0.0 4.1e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) FMN_dh PF01070.18 ORY90111.1 - 1.7e-112 375.9 0.1 2.3e-112 375.5 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 ORY90111.1 - 1.5e-18 66.7 0.0 3e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 ORY90111.1 - 1.9e-05 23.9 0.1 3.1e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 ORY90111.1 - 3.8e-05 23.0 0.1 5.9e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Cytotoxic PF09000.10 ORY90111.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytotoxic Peptidase_M16_C PF05193.21 ORY90112.1 - 3.4e-10 40.2 0.0 2.6e-08 34.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY90112.1 - 5.1e-08 33.0 0.0 2.2e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Actin PF00022.19 ORY90113.1 - 3.7e-127 424.3 0.0 1.7e-126 422.1 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY90113.1 - 0.017 13.9 0.0 0.17 10.7 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein Rad21_Rec8 PF04824.16 ORY90113.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein DUF1115 PF06544.12 ORY90114.1 - 6.1e-08 32.9 0.0 1.1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DNA_ligase_A_M PF01068.21 ORY90116.1 - 4.6e-41 140.7 0.0 1.5e-40 139.1 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY90116.1 - 3e-18 66.8 0.0 6e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY90116.1 - 7.4e-14 52.2 0.0 7.7e-13 48.9 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 ORY90116.1 - 1.5e-13 50.9 0.0 5.7e-10 39.5 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 ORY90116.1 - 5e-10 39.9 0.0 1.5e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 RNA ligase BRCT PF00533.26 ORY90116.1 - 1e-05 25.8 0.0 0.00048 20.5 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 ORY90116.1 - 0.15 12.4 0.0 16 5.9 0.0 3.1 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain ADH_zinc_N PF00107.26 ORY90117.1 - 3.8e-08 33.4 0.0 8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY90117.1 - 4.6e-07 29.7 0.1 9.5e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rdx PF10262.9 ORY90118.1 - 7.3e-24 83.8 0.0 1.3e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Rdx family ADH_zinc_N PF00107.26 ORY90119.1 - 2.9e-09 37.0 0.0 5.1e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY90119.1 - 0.00022 21.0 0.5 0.00059 19.7 0.4 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORY90119.1 - 0.045 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF1134 PF06577.12 ORY90119.1 - 0.091 12.5 0.4 0.16 11.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) MFS_1 PF07690.16 ORY90120.1 - 1.8e-21 76.5 20.3 2.6e-21 76.0 20.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_C97 PF05903.14 ORY90121.1 - 2.5e-21 76.1 0.0 4.8e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 PPPDE putative peptidase domain Lysine_decarbox PF03641.14 ORY90122.1 - 1.6e-32 112.4 0.0 2.2e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ORY90122.1 - 1.9e-11 43.8 0.5 2.5e-11 43.4 0.5 1.2 1 0 0 1 1 1 1 SLOG cluster4 family PhoLip_ATPase_C PF16212.5 ORY90123.1 - 6.4e-78 262.0 17.3 6.4e-78 262.0 17.3 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY90123.1 - 2.5e-27 94.3 3.7 6.6e-27 93.0 3.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORY90123.1 - 3.5e-12 47.1 0.2 1.4e-07 32.0 0.0 3.0 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY90123.1 - 1.9e-11 43.9 0.0 8.2e-11 41.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY90123.1 - 1.6e-06 27.8 0.0 6.8e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY90123.1 - 0.0049 16.6 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Bac_luciferase PF00296.20 ORY90124.1 - 1.7e-53 182.1 0.7 2.7e-53 181.5 0.7 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Endonuc-PvuII PF09225.10 ORY90124.1 - 0.16 11.7 0.2 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease PvuII NUDIX PF00293.28 ORY90125.1 - 5e-13 49.2 0.0 6.5e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain PCI PF01399.27 ORY90126.1 - 1.4e-10 41.6 0.0 3.4e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 PCI domain DLIC PF05783.11 ORY90127.1 - 1.8e-52 178.7 4.1 3.1e-40 138.4 0.0 4.9 3 2 1 4 4 4 4 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 ORY90127.1 - 0.013 15.0 0.0 0.18 11.3 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY90127.1 - 0.065 13.3 0.3 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY90127.1 - 0.065 13.8 0.0 0.17 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY90127.1 - 0.14 12.4 0.1 0.43 10.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.6 ORY90128.1 - 1e-25 90.0 6.8 2.4e-17 63.2 2.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY90128.1 - 5.8e-25 84.9 11.5 3.8e-07 29.2 0.1 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 ORY90128.1 - 6.6e-21 72.4 9.8 7.2e-07 28.6 0.2 5.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 ORY90128.1 - 1.1e-13 50.0 7.3 4e-05 22.9 0.1 4.9 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 ORY90128.1 - 7.6e-13 48.1 6.7 5.5e-05 22.9 0.1 4.5 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 ORY90128.1 - 8.1e-08 32.2 5.8 0.0068 16.3 0.2 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY90128.1 - 0.00021 21.6 2.5 0.8 10.0 1.3 3.5 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORY90128.1 - 0.033 14.5 1.2 0.25 11.7 0.0 2.8 2 2 1 3 3 3 0 EF-hand domain SDH_sah PF01972.16 ORY90128.1 - 0.054 12.5 0.4 0.075 12.0 0.4 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Pan3_PK PF18101.1 ORY90128.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Pan3 Pseudokinase domain HCO3_cotransp PF00955.21 ORY90129.1 - 1.2e-61 209.1 10.3 3.4e-34 118.6 1.9 3.0 2 1 1 3 3 3 3 HCO3- transporter family Dioxygenase_C PF00775.21 ORY90130.1 - 3.4e-07 29.9 0.4 1.4e-06 27.9 0.3 1.9 1 1 0 1 1 1 1 Dioxygenase Lactonase PF10282.9 ORY90131.1 - 6.9e-22 78.2 0.0 9.4e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_1 PF00561.20 ORY90133.1 - 3.3e-17 63.0 0.0 2.1e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY90133.1 - 3.3e-14 54.0 1.5 3.3e-14 54.0 1.5 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY90133.1 - 4.6e-07 29.4 0.0 8.2e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 CMD PF02627.20 ORY90133.1 - 2e-06 27.7 1.2 4e-06 26.8 0.1 2.2 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Peptidase_S9 PF00326.21 ORY90133.1 - 0.0022 17.5 0.0 0.44 10.0 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Esterase PF00756.20 ORY90133.1 - 0.0069 16.1 0.2 0.015 15.0 0.2 1.7 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 ORY90133.1 - 0.21 11.5 0.0 5.1 7.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Tyr_Deacylase PF02580.16 ORY90134.1 - 5.6e-52 176.1 0.0 8.8e-52 175.5 0.0 1.3 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Glyco_hydro_18 PF00704.28 ORY90135.1 - 3e-50 171.7 0.3 3.7e-50 171.4 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fer4_19 PF06902.11 ORY90135.1 - 0.074 13.1 0.0 13 6.0 0.0 2.8 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Git3 PF11710.8 ORY90136.1 - 7.9e-06 25.8 7.4 2.1e-05 24.4 7.4 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ORY90136.1 - 0.0016 18.5 0.8 0.0016 18.5 0.8 3.0 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 ORY90136.1 - 0.013 14.6 7.1 0.022 13.9 7.1 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORY90136.1 - 0.076 12.3 9.6 0.017 14.5 6.3 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RCR PF12273.8 ORY90136.1 - 0.27 11.9 1.2 0.44 11.2 0.2 1.9 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Glyco_hydro_16 PF00722.21 ORY90137.1 - 1.5e-07 31.1 0.1 2.5e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 ORY90138.1 - 0.0029 17.1 0.0 0.049 13.1 0.1 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF4985 PF16373.5 ORY90138.1 - 0.04 14.4 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Git3 PF11710.8 ORY90139.1 - 2.2e-05 24.3 6.7 6e-05 22.9 6.7 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ORY90139.1 - 0.00015 21.8 1.0 0.00088 19.3 1.0 2.3 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 ORY90139.1 - 0.0013 18.0 5.3 0.002 17.3 5.3 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor RRM_1 PF00076.22 ORY90140.1 - 4.3e-10 39.3 0.1 1.9e-06 27.6 0.0 2.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAJIN PF15077.6 ORY90141.1 - 1.9 8.2 4.8 0.84 9.4 0.2 2.1 2 0 0 2 2 2 0 Membrane-anchored junction protein DUF2207 PF09972.9 ORY90143.1 - 0.072 11.8 0.1 0.097 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PLDc_2 PF13091.6 ORY90144.1 - 7.3e-19 68.0 0.0 1.2e-11 44.6 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORY90144.1 - 0.03 14.5 0.3 9.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Phospholipase D Active site motif DUF846 PF05832.12 ORY90146.1 - 5.4e-48 162.6 10.6 6.5e-48 162.3 10.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TMEM220 PF15071.6 ORY90146.1 - 9.2 7.1 7.7 0.6 10.9 0.8 2.2 2 1 0 2 2 2 0 Transmembrane family 220, helix SRP_TPR_like PF17004.5 ORY90147.1 - 1.7e-10 40.9 0.3 2.6e-10 40.3 0.3 1.3 1 0 0 1 1 1 1 Putative TPR-like repeat SRP72 PF08492.12 ORY90147.1 - 1.1e-09 38.6 3.7 1.1e-09 38.6 3.7 2.0 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 ORY90147.1 - 1.3e-05 25.3 7.3 0.0011 19.1 0.1 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY90147.1 - 6.3e-05 23.4 15.1 0.015 15.8 3.9 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY90147.1 - 0.84 9.9 10.1 35 4.8 0.4 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MutS_III PF05192.18 ORY90147.1 - 7 6.8 6.1 27 4.9 0.2 2.0 1 1 1 2 2 2 0 MutS domain III PLDc_2 PF13091.6 ORY90148.1 - 4.1e-18 65.6 0.0 8.7e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 ORY90148.1 - 4.2e-05 23.5 1.5 2 8.7 0.0 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif Leuk-A4-hydro_C PF09127.11 ORY90148.1 - 0.11 12.6 0.1 0.31 11.1 0.1 1.7 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal DUF4470 PF14737.6 ORY90149.1 - 7.9e-20 70.9 0.2 1.8e-19 69.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 ORY90149.1 - 1.5e-09 37.8 12.5 3.3e-09 36.7 12.5 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY90149.1 - 0.018 15.4 10.4 0.039 14.3 10.4 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 ORY90149.1 - 1.7 8.8 7.4 4.3 7.5 7.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DSBA PF01323.20 ORY90150.1 - 2.3e-26 92.8 0.0 3.6e-26 92.1 0.0 1.3 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Mito_carr PF00153.27 ORY90151.1 - 1.8e-63 210.5 3.1 4.5e-21 74.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pinin_SDK_memA PF04696.13 ORY90152.1 - 4.1e-16 59.2 38.4 2.4e-15 56.7 10.3 3.4 3 0 0 3 3 3 2 pinin/SDK/memA/ protein conserved region AAA_11 PF13086.6 ORY90152.1 - 3.7 7.2 14.2 0.17 11.6 2.4 2.1 2 0 0 2 2 2 0 AAA domain Lum_binding PF00677.17 ORY90153.1 - 9.6e-43 144.1 0.2 4.4e-22 77.9 0.6 2.1 2 0 0 2 2 2 2 Lumazine binding domain WD40 PF00400.32 ORY90154.1 - 1.8e-08 34.9 8.1 0.0034 18.2 0.5 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ORY90154.1 - 0.0051 16.4 10.1 0.0051 16.4 10.1 2.2 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type V4R PF02830.18 ORY90155.1 - 0.02 14.9 0.4 0.03 14.3 0.4 1.3 1 0 0 1 1 1 0 V4R domain HSF_DNA-bind PF00447.17 ORY90156.1 - 5.4e-14 52.6 0.0 8.8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding FAD_binding_1 PF00667.20 ORY90157.1 - 1.6e-33 116.1 0.0 2.3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY90157.1 - 6.3e-22 78.3 0.0 1e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY90157.1 - 1e-10 42.2 0.0 1.6e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ORY90157.1 - 0.037 14.3 0.0 0.8 9.9 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain ATE_C PF04377.15 ORY90158.1 - 9.2e-48 162.3 0.1 1.4e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 ORY90158.1 - 4.2e-21 75.1 0.3 8.9e-21 74.1 0.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Astro_capsid_p PF12226.8 ORY90158.1 - 0.4 9.8 3.5 0.67 9.1 3.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ArfGap PF01412.18 ORY90159.1 - 2.2e-34 118.0 0.1 3.3e-34 117.5 0.1 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ORC6 PF05460.13 ORY90159.1 - 4.4 6.5 6.0 6.2 6.0 6.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MRP-S25 PF13741.6 ORY90160.1 - 5.2e-44 150.5 0.0 1.1e-43 149.5 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 ORY90160.1 - 0.039 14.2 0.2 14 6.0 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 EMP24_GP25L PF01105.24 ORY90161.1 - 5.7e-51 173.0 0.3 6.5e-51 172.9 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NmrA PF05368.13 ORY90162.1 - 3.4e-41 141.3 0.1 4.4e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY90162.1 - 2e-15 57.2 0.0 3.1e-15 56.5 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY90162.1 - 5.8e-06 25.9 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 ORY90162.1 - 6.6e-06 26.4 0.0 2.3e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 TrkA-N domain 3Beta_HSD PF01073.19 ORY90162.1 - 1.8e-05 23.9 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 ORY90162.1 - 0.0016 18.7 0.1 0.0027 18.0 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 ORY90162.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 ORY90162.1 - 0.034 14.1 0.1 0.084 12.8 0.0 1.6 2 0 0 2 2 2 0 KR domain Nitro_FeMo-Co PF02579.17 ORY90162.1 - 0.041 14.2 0.1 2.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor DapB_N PF01113.20 ORY90162.1 - 0.042 14.0 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 ORY90162.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.12 ORY90163.1 - 1.3e-26 92.6 0.0 2.4e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY90163.1 - 3.7e-26 91.6 0.0 6.9e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY90163.1 - 8.1e-09 36.6 0.0 1.8e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY90163.1 - 3.4e-07 30.0 0.2 4.2e-05 23.1 0.2 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 ORY90163.1 - 7.3e-06 25.4 0.3 1.1e-05 24.8 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ORY90163.1 - 0.0065 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 ORY90163.1 - 0.0079 16.9 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY90163.1 - 0.029 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sugar_tr PF00083.24 ORY90164.1 - 1.7e-91 307.3 19.6 2.2e-91 307.0 19.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY90164.1 - 2.2e-13 49.9 42.9 1.1e-08 34.4 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.31 ORY90165.1 - 2.7e-38 129.9 1.1 6e-13 48.8 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY90165.1 - 2.1e-25 88.7 0.0 2.3e-10 40.6 0.0 3.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 ORY90165.1 - 0.00069 19.9 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like HTH_31 PF13560.6 ORY90165.1 - 0.0092 16.3 0.2 0.032 14.6 0.2 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain Myb_DNA-bind_4 PF13837.6 ORY90165.1 - 0.018 15.4 0.4 0.83 10.1 0.1 3.0 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 ORY90165.1 - 0.036 14.2 0.1 7.4 6.7 0.0 3.1 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 ORY90165.1 - 0.088 12.7 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Myb DNA-binding like SLIDE PF09111.10 ORY90165.1 - 0.092 12.8 0.0 6.2 6.9 0.0 2.7 2 1 1 3 3 3 0 SLIDE Myb_DNA-bind_5 PF13873.6 ORY90165.1 - 0.11 12.6 1.2 31 4.7 0.0 3.7 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Glyco_hydro_26 PF02156.15 ORY90166.1 - 0.14 11.5 1.1 0.6 9.5 0.8 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 Isochorismatase PF00857.20 ORY90167.1 - 2e-29 103.0 0.1 2.6e-29 102.6 0.1 1.2 1 0 0 1 1 1 1 Isochorismatase family Gcn1_N PF12074.8 ORY90168.1 - 1.2e-81 274.8 2.2 1.2e-81 274.8 2.2 5.1 6 0 0 6 6 6 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 ORY90168.1 - 5.1e-31 104.1 35.6 0.028 14.7 0.1 21.4 24 0 0 24 24 22 8 HEAT repeat HEAT_2 PF13646.6 ORY90168.1 - 5.2e-22 78.0 66.4 4.2e-05 23.9 1.4 17.6 14 4 3 18 18 17 6 HEAT repeats HEAT_EZ PF13513.6 ORY90168.1 - 1.5e-19 70.1 58.5 0.00086 19.8 0.0 18.5 21 0 0 21 21 19 6 HEAT-like repeat CLASP_N PF12348.8 ORY90168.1 - 1.3e-13 51.1 0.0 0.00052 19.7 0.0 5.8 5 1 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 ORY90168.1 - 2.8e-12 47.1 0.0 0.24 12.0 0.0 7.4 7 1 1 8 8 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY90168.1 - 1.8e-11 44.4 0.1 2 8.5 0.0 8.7 7 2 2 9 9 9 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY90168.1 - 1.4e-09 37.1 0.0 0.16 10.5 0.0 6.7 6 1 2 8 8 8 2 Adaptin N terminal region DRIM PF07539.12 ORY90168.1 - 2e-06 26.5 3.6 1.2 7.4 0.4 6.7 6 2 0 7 7 7 2 Down-regulated in metastasis RIX1 PF08167.12 ORY90168.1 - 2.2e-06 27.6 6.8 0.00052 19.8 0.0 6.6 6 1 0 7 7 7 1 rRNA processing/ribosome biogenesis TIP120 PF08623.10 ORY90168.1 - 0.0041 16.9 0.0 26 4.5 0.0 5.2 5 1 1 6 6 6 0 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 ORY90168.1 - 0.028 14.7 1.2 3.6 8.0 0.4 4.7 4 1 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.8 ORY90168.1 - 0.032 14.1 0.3 9.1 6.3 0.1 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) eIF3_subunit PF08597.10 ORY90168.1 - 0.057 13.3 1.1 0.13 12.2 1.1 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4404 PF14357.6 ORY90168.1 - 0.1 13.3 6.7 1.3 9.8 0.0 5.0 5 0 0 5 5 4 0 Domain of unknown function (DUF4404) ParcG PF10274.9 ORY90168.1 - 1 9.5 3.3 2.3e+02 1.8 0.0 5.0 5 0 0 5 5 4 0 Parkin co-regulated protein MMS19_C PF12460.8 ORY90168.1 - 4.7 6.2 18.6 8.3 5.4 0.0 6.8 6 2 1 8 8 8 0 RNAPII transcription regulator C-terminal Nop53 PF07767.11 ORY90169.1 - 5.4e-59 200.6 3.7 7.5e-59 200.1 3.7 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Mito_carr PF00153.27 ORY90170.1 - 2.5e-54 181.2 2.0 1.3e-17 63.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-TRAF PF02176.18 ORY90171.1 - 0.00022 21.8 3.1 0.00022 21.8 3.1 3.2 2 2 2 4 4 4 1 TRAF-type zinc finger Git3 PF11710.8 ORY90172.1 - 1.9e-06 27.8 2.9 1.9e-06 27.8 2.9 1.8 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 ORY90172.1 - 2.9e-05 24.1 0.0 0.00012 22.0 0.0 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 ORY90172.1 - 0.15 11.2 6.8 0.19 10.9 5.6 1.6 1 1 0 1 1 1 0 Slime mold cyclic AMP receptor 7TM_GPCR_Srx PF10328.9 ORY90172.1 - 0.23 11.0 7.8 0.33 10.5 3.9 2.4 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx UCH PF00443.29 ORY90173.1 - 1.3e-41 142.8 0.0 5.5e-41 140.8 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 ORY90173.1 - 3.8e-22 78.0 0.1 2.8e-06 27.2 0.1 3.6 3 0 0 3 3 3 3 A repeated domain in UCH-protein UCH_1 PF13423.6 ORY90173.1 - 1.7e-08 34.4 0.8 0.0044 16.7 0.1 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase IPP-2 PF04979.14 ORY90174.1 - 5.8e-05 23.8 0.3 7.4e-05 23.5 0.3 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) IPP-2 PF04979.14 ORY90175.1 - 3.5e-10 40.7 0.6 5.9e-10 40.0 0.1 1.6 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) SMK-1 PF04802.15 ORY90176.1 - 5e-66 222.2 0.0 7.9e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Zn_clus PF00172.18 ORY90178.1 - 3.2e-06 27.2 6.9 6.4e-06 26.2 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_12 PF17976.1 ORY90178.1 - 0.42 10.9 3.2 0.9 9.9 3.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HMG14_17 PF01101.18 ORY90178.1 - 0.5 11.4 7.8 0.95 10.5 7.8 1.4 1 0 0 1 1 1 0 HMG14 and HMG17 zf-TRAF PF02176.18 ORY90179.1 - 0.001 19.7 1.9 0.001 19.7 1.9 2.3 2 1 0 2 2 2 1 TRAF-type zinc finger DUF4366 PF14283.6 ORY90179.1 - 0.02 14.9 0.1 0.02 14.9 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4366) TMEM154 PF15102.6 ORY90179.1 - 0.023 14.6 0.2 0.023 14.6 0.2 2.7 3 0 0 3 3 3 0 TMEM154 protein family HemX PF04375.14 ORY90179.1 - 0.044 13.1 2.2 0.91 8.8 0.0 2.5 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase ABC_membrane PF00664.23 ORY90180.1 - 1.3e-47 162.8 4.6 2.4e-36 125.8 0.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY90180.1 - 5.2e-33 114.5 0.0 1.1e-32 113.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORY90180.1 - 8.8e-06 26.2 0.8 3.9e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain ABC_ATPase PF09818.9 ORY90180.1 - 6.5e-05 21.9 0.4 0.015 14.2 0.1 2.5 2 0 0 2 2 2 2 Predicted ATPase of the ABC class SMC_N PF02463.19 ORY90180.1 - 0.00019 20.9 0.0 0.011 15.2 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 ORY90180.1 - 0.0025 17.1 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 ORY90180.1 - 0.0027 18.0 0.4 0.044 14.1 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY90180.1 - 0.0094 16.2 0.0 0.041 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY90180.1 - 0.011 15.4 0.4 0.028 14.2 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 ORY90180.1 - 0.059 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 ORY90180.1 - 0.07 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase zf-CCHC PF00098.23 ORY90181.1 - 1.6e-08 34.3 27.9 9.7e-06 25.4 0.5 5.1 4 1 0 4 4 4 3 Zinc knuckle Nitrate_red_del PF02613.15 ORY90181.1 - 0.00065 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Nitrate reductase delta subunit zf-CCHC_2 PF13696.6 ORY90181.1 - 0.011 15.6 0.3 0.011 15.6 0.3 4.0 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC_3 PF13917.6 ORY90181.1 - 0.28 11.2 15.2 1.1 9.3 0.9 3.4 2 1 1 3 3 3 0 Zinc knuckle PGA2 PF07543.12 ORY90181.1 - 5.4 7.0 14.2 4.8 7.2 3.4 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 ORY90181.1 - 6.8 7.2 14.4 2.2 8.7 8.9 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EMC3_TMCO1 PF01956.16 ORY90182.1 - 1.5e-49 168.0 0.0 1.9e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like THF_DHG_CYH PF00763.23 ORY90183.1 - 6.5e-26 90.9 0.0 1.1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 ORY90183.1 - 1.6e-11 43.8 0.5 1.9e-07 30.6 0.0 3.2 3 1 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 ORY90184.1 - 5.8e-25 88.0 45.6 2.5e-22 79.3 33.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SSF PF00474.17 ORY90185.1 - 5.3e-16 58.5 22.4 1e-15 57.5 22.4 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family TPX2 PF06886.11 ORY90186.1 - 0.00075 19.7 16.9 0.00075 19.7 16.9 3.5 3 0 0 3 3 3 1 Targeting protein for Xklp2 (TPX2) RNA_pol_Rpb2_6 PF00562.28 ORY90187.1 - 1.9e-110 369.6 0.0 3.9e-110 368.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY90187.1 - 8.6e-34 116.8 0.0 1.4e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 ORY90187.1 - 2e-27 95.2 0.0 4.3e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 ORY90187.1 - 2e-24 85.3 0.0 6.3e-24 83.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 ORY90187.1 - 2.9e-21 76.0 0.0 4.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORY90187.1 - 1.3e-18 67.1 0.2 9.9e-15 54.7 0.4 2.6 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 7 ING PF12998.7 ORY90188.1 - 1.4e-12 48.1 0.1 1.4e-12 48.1 0.1 2.1 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY90188.1 - 5.9e-05 22.9 7.1 9.6e-05 22.2 7.1 1.3 1 0 0 1 1 1 1 PHD-finger DUF3450 PF11932.8 ORY90188.1 - 0.001 18.5 6.8 0.12 11.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) PHD_2 PF13831.6 ORY90188.1 - 0.0049 16.4 1.5 0.0078 15.7 1.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORY90188.1 - 0.15 12.3 2.1 0.31 11.3 2.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Spt20 PF12090.8 ORY90188.1 - 5.2 6.6 10.5 9.8 5.7 10.5 1.4 1 0 0 1 1 1 0 Spt20 family Ran_BP1 PF00638.18 ORY90189.1 - 1.7e-49 167.1 0.1 2.6e-49 166.6 0.1 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 ORY90189.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 WH1 domain Pex2_Pex12 PF04757.14 ORY90190.1 - 6.4e-31 107.7 1.9 8.1e-31 107.4 1.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region FAD_binding_6 PF00970.24 ORY90191.1 - 9e-11 42.0 0.0 2.3e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY90191.1 - 3.2e-06 27.7 0.2 0.00076 20.1 0.2 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY90191.1 - 0.00086 19.5 0.4 1.1 9.4 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain PseudoU_synth_2 PF00849.22 ORY90192.1 - 2.9e-22 79.5 0.0 4.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-box-like PF12937.7 ORY90193.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like tRNA-synt_2d PF01409.20 ORY90195.1 - 1.2e-90 303.2 0.1 1.8e-90 302.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 ORY90195.1 - 1.4e-19 70.1 2.8 1.6e-19 69.9 0.3 2.5 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 ORY90195.1 - 1.5e-10 40.9 0.0 6.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 ORY90195.1 - 3.5e-05 23.0 0.7 0.0021 17.2 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 ORY90195.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 ORY90195.1 - 0.0052 16.7 0.2 0.01 15.8 0.2 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 zf-C3HC4 PF00097.25 ORY90196.1 - 0.0019 18.0 7.4 0.0026 17.6 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY90196.1 - 0.0061 16.6 5.8 0.0096 15.9 5.8 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY90196.1 - 0.02 15.2 9.9 0.029 14.7 9.9 1.2 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 ORY90196.1 - 0.024 14.6 5.4 0.035 14.1 5.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY90196.1 - 0.046 13.9 6.2 0.065 13.4 6.2 1.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY90196.1 - 0.31 11.4 5.7 0.47 10.8 5.7 1.3 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY90196.1 - 0.53 10.2 5.7 0.78 9.7 5.7 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Thioredoxin_4 PF13462.6 ORY90197.1 - 9.7e-08 32.3 0.0 7.9e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin YbjQ_1 PF01906.17 ORY90198.1 - 0.036 14.7 0.3 0.036 14.7 0.3 2.0 2 0 0 2 2 2 0 Putative heavy-metal-binding DUF3649 PF12365.8 ORY90200.1 - 0.0086 15.8 1.1 0.015 15.0 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3649) OppC_N PF12911.7 ORY90200.1 - 0.014 15.3 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SOG2 PF10428.9 ORY90200.1 - 0.062 12.5 0.1 0.077 12.2 0.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3328 PF11807.8 ORY90200.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) HSP90 PF00183.18 ORY90201.1 - 4.2e-138 461.5 0.1 5.7e-138 461.0 0.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 ORY90201.1 - 2e-10 40.6 0.0 4.9e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY90201.1 - 9.5e-07 29.3 0.0 2.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phosphonate-bd PF12974.7 ORY90201.1 - 0.046 13.3 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Secretin_N PF03958.17 ORY90201.1 - 0.065 13.6 0.1 1 9.8 0.1 2.8 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain Glyco_hydro_76 PF03663.14 ORY90202.1 - 6.6e-34 118.0 12.4 8.8e-34 117.6 12.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ORY90202.1 - 0.00013 21.2 0.6 0.73 8.9 0.1 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 PAT1 PF09770.9 ORY90203.1 - 7e-118 395.2 54.8 6.1e-104 349.1 13.8 4.0 3 1 0 3 3 3 3 Topoisomerase II-associated protein PAT1 RhoGAP PF00620.27 ORY90204.1 - 1.8e-42 144.7 0.0 3.2e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY90204.1 - 3.7e-14 53.1 0.0 7.2e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 ORY90204.1 - 2.4e-05 24.5 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PX PF00787.24 ORY90204.1 - 2.4e-05 24.3 0.0 5.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 ORY90204.1 - 0.0064 16.9 0.1 0.05 14.0 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain SET PF00856.28 ORY90205.1 - 7.6e-12 45.9 0.0 1.9e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 SET domain Rubredoxin PF00301.20 ORY90205.1 - 0.46 10.5 1.6 3.1 7.9 1.6 2.1 2 0 0 2 2 2 0 Rubredoxin EamA PF00892.20 ORY90206.1 - 1.9e-05 24.8 9.7 1.9e-05 24.8 9.7 2.1 2 0 0 2 2 2 1 EamA-like transporter family LapA_dom PF06305.11 ORY90206.1 - 0.096 12.5 0.6 7.4 6.5 0.0 3.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RhoGEF PF00621.20 ORY90207.1 - 2.4e-11 44.2 0.0 2.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain His_Phos_1 PF00300.22 ORY90208.1 - 8.9e-42 143.0 0.0 1.3e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L37ae PF01780.19 ORY90209.1 - 2.6e-40 136.4 12.5 2.9e-40 136.3 12.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 ORY90209.1 - 0.0011 19.0 4.5 0.0016 18.5 4.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 ORY90209.1 - 0.0016 18.4 2.1 0.0025 17.8 2.1 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 ORY90209.1 - 0.02 14.9 1.0 0.028 14.5 1.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_2 PF03107.16 ORY90209.1 - 0.16 12.3 2.9 1.1 9.7 3.2 1.9 1 1 0 1 1 1 0 C1 domain CarbpepA_inh PF02977.15 ORY90209.1 - 0.44 10.4 6.0 1.7 8.5 6.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.6 ORY90209.1 - 0.45 11.0 6.8 3.8 8.1 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 ORY90209.1 - 2.4 8.3 5.2 7.2 6.8 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-CHCC PF10276.9 ORY90210.1 - 1.4e-13 50.6 1.6 2.1e-13 50.0 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 ORY90210.1 - 0.069 12.9 0.3 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 Zinc Finger domain CNH PF00780.22 ORY90211.1 - 2.6e-47 161.8 0.0 3.6e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY90211.1 - 3.7e-26 92.5 0.0 6e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 ORY90211.1 - 3.6e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 ORY90211.1 - 0.003 17.6 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Prenyltransf PF01255.19 ORY90212.1 - 1.5e-69 233.9 0.0 1.9e-69 233.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF4909 PF16253.5 ORY90212.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4909) Polysacc_synt_4 PF04669.13 ORY90213.1 - 5e-18 65.3 1.3 2.5e-16 59.8 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 ORY90213.1 - 0.027 14.2 0.1 0.07 12.8 0.1 1.8 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Gluconate_2-dh3 PF13618.6 ORY90213.1 - 0.069 13.4 0.2 0.089 13.0 0.2 1.3 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF2262 PF10020.9 ORY90213.1 - 0.41 11.0 4.9 0.62 10.4 4.8 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) DLH PF01738.18 ORY90215.1 - 1.3e-21 77.2 0.0 1.5e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 ORY90215.1 - 0.088 12.7 0.0 0.23 11.3 0.0 1.6 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal RGI1 PF10843.8 ORY90215.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Respiratory growth induced protein 1 Peptidase_S15 PF02129.18 ORY90215.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) NUFIP1 PF10453.9 ORY90216.1 - 1.4e-14 53.6 0.4 3.1e-14 52.5 0.4 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Torus PF16131.5 ORY90216.1 - 0.0021 18.7 0.0 0.0049 17.5 0.0 1.5 1 0 0 1 1 1 1 Torus domain Pinin_SDK_N PF04697.13 ORY90216.1 - 0.0025 18.4 7.1 0.0096 16.6 7.1 2.0 1 0 0 1 1 1 1 pinin/SDK conserved region Cwf_Cwc_15 PF04889.12 ORY90216.1 - 0.015 15.0 2.5 0.015 15.0 2.5 2.7 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein AF-4 PF05110.13 ORY90216.1 - 0.016 13.4 13.6 0.022 12.9 13.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Herpes_UL17 PF04559.12 ORY90216.1 - 0.13 11.1 0.6 0.2 10.4 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL17 protein Herpes_capsid PF06112.11 ORY90216.1 - 0.41 10.7 6.9 0.97 9.5 6.9 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FoP_duplication PF13865.6 ORY90216.1 - 1.5 9.5 14.0 0.48 11.0 10.4 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF737 PF05300.11 ORY90217.1 - 1.7 9.0 11.3 7 7.0 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Peptidase_M20 PF01546.28 ORY90218.1 - 5.8e-36 124.1 0.4 8.4e-36 123.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY90218.1 - 1.6e-17 63.4 0.1 4.1e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain MFS_1 PF07690.16 ORY90219.1 - 2.6e-30 105.6 18.9 3.8e-30 105.0 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TraX PF05857.11 ORY90219.1 - 0.12 12.4 4.7 0.1 12.6 1.0 2.3 2 0 0 2 2 2 0 TraX protein DUF2681 PF10883.8 ORY90219.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Metallothio_11 PF02066.15 ORY90220.1 - 0.2 11.8 2.3 0.63 10.3 0.1 2.4 2 0 0 2 2 2 0 Metallothionein family 11 VPS13_mid_rpt PF16910.5 ORY90221.1 - 5.8e-95 317.2 8.9 2.8e-93 311.7 0.0 5.2 4 1 1 5 5 5 1 Repeating coiled region of VPS13 VPS13 PF16908.5 ORY90221.1 - 4.8e-82 275.3 0.5 1.6e-78 263.8 0.0 3.8 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 ORY90221.1 - 2.1e-75 253.6 0.0 3.5e-73 246.3 0.0 3.4 4 0 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 ORY90221.1 - 5.8e-72 241.2 5.1 2.8e-66 222.7 0.2 2.7 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 ORY90221.1 - 9.2e-37 125.7 0.0 2.6e-36 124.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORY90221.1 - 3.3e-08 33.8 0.0 4e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Mpv17_PMP22 PF04117.12 ORY90222.1 - 0.00085 19.5 4.1 0.0013 19.0 3.1 1.8 1 1 1 2 2 2 1 Mpv17 / PMP22 family DUF3278 PF11683.8 ORY90222.1 - 0.0099 16.0 1.3 3.7 7.6 0.2 2.2 1 1 0 2 2 2 2 Protein of unknown function (DUF3278) F-box-like PF12937.7 ORY90223.1 - 7.1e-08 32.2 0.3 1.8e-07 30.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like PilN PF05137.13 ORY90223.1 - 0.0086 16.2 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) F-box PF00646.33 ORY90223.1 - 0.075 12.9 0.0 0.3 11.0 0.0 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY90224.1 - 0.0034 17.2 0.7 0.0076 16.1 0.7 1.6 1 0 0 1 1 1 1 F-box-like LSM PF01423.22 ORY90225.1 - 5.3e-19 67.7 0.1 7.7e-19 67.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY90225.1 - 0.0074 15.9 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Hfq protein CBF PF03914.17 ORY90226.1 - 7.9e-48 162.7 0.3 7.9e-48 162.7 0.3 4.0 4 1 0 4 4 4 1 CBF/Mak21 family Cnd1 PF12717.7 ORY90226.1 - 0.099 12.7 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Gti1_Pac2 PF09729.9 ORY90227.1 - 2.4e-49 167.9 0.0 1.1e-47 162.5 0.0 2.0 1 1 0 1 1 1 1 Gti1/Pac2 family Kdo PF06293.14 ORY90228.1 - 7.2e-08 32.0 0.0 2.3e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY90228.1 - 0.00028 20.5 0.0 0.042 13.5 0.0 2.2 1 1 0 1 1 1 1 RIO1 family EcKinase PF02958.20 ORY90228.1 - 0.0097 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 ORY90228.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY90228.1 - 0.041 13.3 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Glyco_hydro_28 PF00295.17 ORY90229.1 - 3.1e-45 154.7 3.9 4.1e-45 154.3 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 ORY90229.1 - 0.038 13.8 12.5 0.7 9.7 13.0 2.4 1 1 1 2 2 2 0 Right handed beta helix region ADH_N_2 PF16884.5 ORY90230.1 - 7.1e-18 64.5 0.0 1.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORY90230.1 - 3.3e-16 59.4 0.0 7.3e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY90230.1 - 0.00075 20.6 0.0 0.0014 19.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 ORY90230.1 - 0.00092 19.0 0.3 0.0015 18.3 0.3 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_10 PF13460.6 ORY90230.1 - 0.055 13.4 0.2 0.088 12.7 0.2 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_16 PF00722.21 ORY90231.1 - 1e-18 67.5 0.0 1.5e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Tubulin PF00091.25 ORY90232.1 - 1.4e-70 237.6 0.0 3e-70 236.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY90232.1 - 3.5e-41 140.3 0.2 6.3e-41 139.5 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY90232.1 - 2.5e-05 24.6 0.6 4.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 ORY90232.1 - 0.0023 17.2 0.0 0.0096 15.1 0.0 1.8 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 ORY90232.1 - 0.0055 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Glyco_hydro_16 PF00722.21 ORY90233.1 - 2e-15 56.7 2.1 2.2e-15 56.6 0.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 ORY90234.1 - 4.6e-15 55.5 0.9 4.6e-15 55.5 0.9 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 DUF1180 PF06679.12 ORY90234.1 - 8 6.8 7.5 13 6.1 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CBFD_NFYB_HMF PF00808.23 ORY90235.1 - 1e-11 44.9 0.1 1.5e-11 44.4 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY90235.1 - 0.00067 20.0 2.6 0.0034 17.7 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Ribosomal_60s PF00428.19 ORY90235.1 - 0.15 12.7 14.3 0.63 10.7 14.3 1.9 1 1 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.6 ORY90235.1 - 3.6 8.0 15.8 26 5.2 11.5 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIS_M PF07500.14 ORY90236.1 - 9e-29 100.2 0.4 2e-28 99.1 0.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 ORY90236.1 - 5.6e-17 61.3 4.9 9.3e-17 60.6 4.9 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 ORY90236.1 - 3.7e-15 55.7 1.9 6.8e-15 54.8 1.9 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Elf1 PF05129.13 ORY90236.1 - 0.0047 16.9 0.5 0.0094 16.0 0.5 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Nucleo_P87 PF07267.11 ORY90236.1 - 0.022 13.6 2.0 0.04 12.8 2.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HTH_22 PF13309.6 ORY90236.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 HTH domain Ndc1_Nup PF09531.10 ORY90236.1 - 2.5 6.7 4.5 3.2 6.3 4.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Abhydrolase_1 PF00561.20 ORY90237.1 - 7.6e-42 143.7 0.0 2.5e-41 142.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY90237.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.14 ORY90238.1 - 6.6e-34 117.3 0.0 3.1e-33 115.1 0.0 2.0 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 ORY90238.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Palm_thioest PF02089.15 ORY90238.1 - 0.0077 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 ORY90238.1 - 0.015 15.9 0.2 0.035 14.7 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY90238.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DLH PF01738.18 ORY90238.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family F-box-like PF12937.7 ORY90240.1 - 1e-07 31.7 0.6 4.8e-07 29.6 0.6 2.3 1 0 0 1 1 1 1 F-box-like PilN PF05137.13 ORY90240.1 - 0.004 17.2 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 Fimbrial assembly protein (PilN) F-box PF00646.33 ORY90240.1 - 0.091 12.7 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 F-box domain CitG PF01874.16 ORY90241.1 - 0.055 13.1 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase DUF3808 PF10300.9 ORY90242.1 - 1.3e-79 268.2 0.0 2.2e-79 267.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_1 PF00515.28 ORY90242.1 - 0.00017 21.3 12.4 0.0014 18.4 0.1 5.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY90242.1 - 0.00032 20.9 6.9 0.0082 16.4 0.1 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY90242.1 - 0.00083 19.3 12.7 0.011 15.8 0.2 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY90242.1 - 0.0039 17.1 0.2 0.065 13.3 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY90242.1 - 0.01 16.4 4.3 0.14 12.9 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY90242.1 - 0.2 12.0 0.2 0.2 12.0 0.2 4.8 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY90242.1 - 0.71 9.8 5.4 0.91 9.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF572 PF04502.13 ORY90243.1 - 0.32 10.6 5.6 0.42 10.2 5.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GREB1 PF15782.5 ORY90243.1 - 5.9 3.9 9.6 7.3 3.6 9.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RGS PF00615.19 ORY90244.1 - 1.1e-31 109.5 0.0 2.2e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 ORY90244.1 - 1.1e-11 44.6 0.0 4.7e-05 23.4 0.0 3.4 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PadR PF03551.14 ORY90244.1 - 0.022 14.7 0.0 4.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Mrr_N PF14338.6 ORY90244.1 - 0.16 12.1 0.0 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Mrr N-terminal domain Pox_A_type_inc PF04508.12 ORY90245.1 - 0.0071 16.2 2.3 0.018 14.9 0.7 2.4 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat DUF1635 PF07795.11 ORY90245.1 - 0.33 10.8 17.2 0.16 11.8 5.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) F-box-like PF12937.7 ORY90246.1 - 2.5e-06 27.3 0.8 4.7e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY90246.1 - 0.011 15.6 0.1 0.061 13.2 0.1 2.4 1 1 0 1 1 1 0 F-box domain Mgm101p PF06420.12 ORY90248.1 - 1.2e-83 278.8 0.0 1.5e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 F-box-like PF12937.7 ORY90251.1 - 0.0012 18.7 0.6 0.0027 17.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like HNH_5 PF14279.6 ORY90251.1 - 0.066 13.1 1.0 0.11 12.3 1.0 1.3 1 0 0 1 1 1 0 HNH endonuclease DUF2635 PF10948.8 ORY90251.1 - 0.14 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) B12D PF06522.11 ORY90253.1 - 2.4e-19 68.9 0.2 3.3e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit NPBW PF15180.6 ORY90253.1 - 0.13 12.2 0.1 0.18 11.6 0.1 1.4 1 1 0 1 1 1 0 Neuropeptides B and W COX7a PF02238.15 ORY90254.1 - 4.7e-13 49.3 1.1 5.3e-13 49.1 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII OEP PF02321.18 ORY90256.1 - 6.5e-05 22.8 3.0 6.5e-05 22.8 3.0 7.1 5 2 1 8 8 8 2 Outer membrane efflux protein Filament PF00038.21 ORY90256.1 - 0.00013 21.7 107.6 0.01 15.4 19.3 6.2 1 1 5 6 6 6 4 Intermediate filament protein Spc7 PF08317.11 ORY90256.1 - 0.00018 20.5 131.9 0.0033 16.3 26.8 7.2 2 1 5 8 8 8 6 Spc7 kinetochore protein UPF0242 PF06785.11 ORY90256.1 - 0.0013 18.9 7.5 0.0013 18.9 7.5 8.1 2 1 5 7 7 7 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 ORY90256.1 - 0.0035 17.6 20.0 0.0035 17.6 20.0 8.9 3 2 5 8 8 8 2 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 ORY90256.1 - 0.41 10.1 111.0 0.011 15.2 19.5 6.9 2 1 2 6 6 6 0 Hyaluronan mediated motility receptor N-terminal Tetraspanin PF00335.20 ORY90257.1 - 0.065 12.9 0.3 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Tetraspanin family Acetyltransf_10 PF13673.7 ORY90258.1 - 3.6e-13 49.6 0.2 1.4e-11 44.4 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY90258.1 - 8e-09 35.8 0.0 1.5e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 ORY90258.1 - 1.5e-06 28.8 0.0 1e-05 26.2 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY90258.1 - 3.9e-05 23.9 0.0 0.00046 20.4 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY90259.1 - 2.5e-16 59.7 0.0 6.2e-15 55.3 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY90259.1 - 1.3e-11 44.7 0.0 1.8e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY90259.1 - 1.2e-09 38.4 0.1 4.3e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY90259.1 - 4.2e-09 36.3 0.2 1e-07 31.8 0.2 2.3 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_5 PF13444.6 ORY90259.1 - 0.00014 22.5 0.0 0.022 15.5 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY90259.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase NAD_binding_6 PF08030.12 ORY90260.1 - 3.8e-14 53.1 0.0 6.1e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY90260.1 - 2.7e-10 40.4 11.3 4.4e-10 39.8 10.2 1.9 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY90260.1 - 0.00012 22.1 0.2 0.00043 20.3 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_7 PF03441.14 ORY90261.1 - 1.1e-53 181.7 0.8 1.7e-53 181.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY90261.1 - 2.8e-25 89.2 0.0 4.7e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase F-box-like PF12937.7 ORY90262.1 - 2.7e-07 30.4 0.2 5.8e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY90262.1 - 0.02 14.7 0.0 0.062 13.2 0.0 1.9 1 0 0 1 1 1 0 F-box domain MFS_1 PF07690.16 ORY90263.1 - 2.6e-40 138.5 45.0 2.6e-40 138.5 45.0 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY90263.1 - 6.5e-15 54.6 14.7 6.5e-15 54.6 14.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY90263.1 - 8.8e-14 51.2 10.8 8.8e-14 51.2 10.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter WD40 PF00400.32 ORY90264.1 - 2.3e-06 28.2 19.9 0.051 14.5 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Prp18 PF02840.15 ORY90264.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Prp18 domain Sec16_C PF12931.7 ORY90264.1 - 0.051 13.2 0.2 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 Glyco_hydro_127 PF07944.12 ORY90264.1 - 0.06 11.8 0.2 0.089 11.3 0.2 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 SRA1 PF07304.11 ORY90264.1 - 0.077 12.8 0.0 0.077 12.8 0.0 4.0 4 1 1 5 5 5 0 Steroid receptor RNA activator (SRA1) Zn_clus PF00172.18 ORY90265.1 - 0.0012 18.9 5.3 0.0022 18.1 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Anti-TRAP PF15777.5 ORY90265.1 - 2.9 7.9 5.7 6 6.9 5.7 1.5 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein MnhB PF04039.13 ORY90268.1 - 1.2 9.4 8.4 0.33 11.3 1.4 2.8 2 1 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter LNS2 PF08235.13 ORY90269.1 - 1.1e-101 339.1 0.0 1.6e-101 338.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 ORY90269.1 - 2.9e-34 117.1 0.0 6.2e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 ORY90269.1 - 2.2e-21 75.9 0.0 4.6e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Nuc_deoxyri_tr3 PF11071.8 ORY90269.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase YtoQ Radial_spoke PF04712.12 ORY90269.1 - 3.7 6.4 10.4 7.1 5.5 10.4 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein Phage_Gp23 PF10669.9 ORY90271.1 - 4.8 7.6 6.9 18 5.7 6.9 1.9 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) AFG1_ATPase PF03969.16 ORY90273.1 - 3.2e-58 197.4 0.0 3.3e-51 174.3 0.0 4.5 3 1 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 ORY90273.1 - 5.7e-07 30.1 0.0 2.8e-06 27.8 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY90273.1 - 0.00068 19.9 0.0 0.0029 17.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY90273.1 - 0.0046 16.5 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 ORY90273.1 - 0.011 16.2 0.0 0.035 14.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY90273.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RbcS PF12338.8 ORY90273.1 - 0.026 14.7 3.0 0.058 13.6 3.0 1.6 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit IstB_IS21 PF01695.17 ORY90273.1 - 0.029 14.1 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_19 PF13245.6 ORY90273.1 - 0.075 13.4 0.0 0.42 10.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORY90273.1 - 0.076 12.4 0.1 0.76 9.1 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY90273.1 - 0.088 12.8 0.0 0.3 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RTA1 PF04479.13 ORY90274.1 - 5.3e-53 179.7 8.4 7.2e-53 179.3 8.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Methyltransf_11 PF08241.12 ORY90275.1 - 1e-13 51.7 0.0 2.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY90275.1 - 5.2e-12 46.3 0.0 1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY90275.1 - 1e-11 44.9 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY90275.1 - 4.7e-07 30.5 0.0 9.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY90275.1 - 4.7e-05 23.2 0.0 0.00017 21.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY90275.1 - 0.00038 19.9 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORY90275.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 ORY90275.1 - 0.082 11.5 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_S10 PF00450.22 ORY90276.1 - 6.4e-103 345.4 0.0 8.3e-103 345.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_18 PF00704.28 ORY90277.1 - 1.3e-43 150.0 4.1 1.6e-43 149.6 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CDC45 PF02724.14 ORY90277.1 - 0.0004 18.8 3.2 0.00063 18.2 3.2 1.3 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 ORY90277.1 - 0.0073 14.6 3.4 0.0095 14.2 3.4 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2981 PF11200.8 ORY90278.1 - 0.57 9.9 3.4 0.92 9.2 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) GREB1 PF15782.5 ORY90278.1 - 3.5 4.6 11.7 4.5 4.3 11.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Miga PF10265.9 ORY90278.1 - 5.7 5.8 11.0 8 5.3 11.0 1.2 1 0 0 1 1 1 0 Mitoguardin GTP_cyclohydro2 PF00925.20 ORY90279.1 - 1.8e-64 216.3 0.0 3e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II tRNA_m1G_MT PF01746.21 ORY90280.1 - 2.5e-27 95.9 0.0 1.9e-22 79.9 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Mpp10 PF04006.12 ORY90281.1 - 2.7e-108 363.1 66.9 4.1e-86 289.8 33.3 2.2 2 0 0 2 2 2 2 Mpp10 protein Hydrolase_like PF13242.6 ORY90282.1 - 0.00028 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like ThiF PF00899.21 ORY90283.1 - 2.9e-96 321.5 0.0 2.5e-67 226.8 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 ORY90283.1 - 5e-86 288.7 0.0 7.7e-86 288.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 ORY90283.1 - 2.1e-33 114.9 0.1 4.2e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 ORY90283.1 - 1.5e-25 89.2 0.0 3.4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 ORY90283.1 - 6.7e-24 83.9 1.2 9.9e-24 83.3 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle DUF2336 PF10098.9 ORY90284.1 - 0.019 14.5 0.9 0.036 13.6 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2336) Zn_clus PF00172.18 ORY90286.1 - 0.022 14.9 7.3 0.032 14.3 7.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S3_C PF00189.20 ORY90287.1 - 1.3e-24 86.5 0.5 5.5e-24 84.5 0.2 2.1 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORY90287.1 - 9.8e-14 50.9 0.0 1.6e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 ORY90287.1 - 0.15 11.8 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus UN_NPL4 PF11543.8 ORY90287.1 - 0.15 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Pro_CA PF00484.19 ORY90289.1 - 4.1e-10 40.2 0.2 7.3e-10 39.4 0.2 1.5 1 1 0 1 1 1 1 Carbonic anhydrase Ribosomal_L22e PF01776.17 ORY90290.1 - 7.7e-40 135.7 0.0 9.7e-40 135.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family LIM PF00412.22 ORY90291.1 - 9.3e-05 22.6 0.2 0.0003 20.9 0.2 1.8 1 1 0 1 1 1 1 LIM domain Vps39_2 PF10367.9 ORY90291.1 - 0.037 14.5 0.1 0.064 13.7 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Ribosom_S12_S23 PF00164.25 ORY90292.1 - 8.2e-50 167.2 1.0 1e-49 166.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF2431 PF10354.9 ORY90293.1 - 7.2e-49 166.3 0.0 1.1e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Presenilin PF01080.17 ORY90293.1 - 3.4 6.3 5.5 4.2 6.0 2.9 2.0 2 0 0 2 2 2 0 Presenilin Amidase PF01425.21 ORY90294.1 - 5.8e-92 309.0 0.0 8e-92 308.5 0.0 1.2 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.13 ORY90294.1 - 0.0018 18.4 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0180) F-box-like PF12937.7 ORY90295.1 - 0.13 12.1 0.3 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 ORY90296.1 - 0.003 17.4 0.4 0.0077 16.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like Glyco_transf_90 PF05686.12 ORY90297.1 - 8e-18 64.5 1.5 1.1e-16 60.7 0.3 2.4 3 0 0 3 3 3 2 Glycosyl transferase family 90 CLU PF13236.6 ORY90299.1 - 9.1e-73 244.7 0.1 3e-72 243.1 0.0 1.8 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 ORY90299.1 - 6e-47 159.9 0.0 1.4e-46 158.7 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 ORY90299.1 - 4.3e-15 55.8 0.3 1.5e-05 25.2 0.4 4.6 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 ORY90299.1 - 5.6e-07 29.2 1.5 0.024 14.5 0.1 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF727 PF05303.12 ORY90299.1 - 0.0045 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) CLU_N PF15044.6 ORY90299.1 - 0.1 13.0 0.0 5.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial function, CLU-N-term PHD PF00628.29 ORY90300.1 - 1.7e-09 37.4 4.3 3.9e-09 36.2 4.3 1.7 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.8 ORY90300.1 - 0.0022 17.8 0.1 0.0022 17.8 0.1 2.9 3 1 1 4 4 4 1 CpG binding protein zinc finger C terminal domain KH_1 PF00013.29 ORY90302.1 - 2.4e-39 133.0 8.0 3.8e-15 55.5 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY90302.1 - 4.4e-09 36.0 5.4 0.048 13.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY90302.1 - 8.2e-09 35.2 1.1 0.016 15.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY90302.1 - 0.00014 21.9 6.7 0.023 14.8 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain BCIP PF13862.6 ORY90303.1 - 3e-68 229.6 0.0 3.9e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein adh_short_C2 PF13561.6 ORY90304.1 - 1.3e-55 188.5 0.2 1.8e-55 188.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY90304.1 - 2.1e-45 154.6 0.8 2.9e-45 154.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY90304.1 - 1.5e-05 25.0 0.6 4.2e-05 23.5 0.6 1.7 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 ORY90304.1 - 0.024 14.4 0.3 0.073 12.8 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 ORY90304.1 - 0.027 13.9 0.3 0.12 11.8 0.3 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 ORY90304.1 - 0.053 12.9 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) EthD PF07110.11 ORY90305.1 - 3.2e-16 60.3 0.0 4.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 ORY90305.1 - 2.1e-05 25.0 0.1 3.6e-05 24.2 0.1 1.5 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase Rhamnogal_lyase PF06045.11 ORY90305.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.4 1 1 0 1 1 1 0 Rhamnogalacturonate lyase family Sugar_tr PF00083.24 ORY90306.1 - 2.5e-83 280.5 27.4 1.9e-70 238.0 16.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY90306.1 - 2.8e-24 85.7 40.3 3.4e-10 39.4 2.9 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Dioxygenase_C PF00775.21 ORY90307.1 - 7.8e-46 155.8 0.0 1.1e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 ORY90307.1 - 9.2e-30 102.3 0.0 1.5e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 ORY90307.1 - 0.066 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Zn_clus PF00172.18 ORY90308.1 - 7.8e-07 29.1 8.9 1.3e-06 28.4 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY90308.1 - 6.6e-05 22.1 0.2 0.00012 21.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UPF0506 PF11703.8 ORY90308.1 - 0.32 11.4 4.4 0.63 10.5 4.4 1.4 1 0 0 1 1 1 0 UPF0506 MMM1 PF10296.9 ORY90309.1 - 1.4e-59 201.9 0.0 4.1e-50 170.7 0.0 2.6 1 1 1 2 2 2 2 Maintenance of mitochondrial morphology protein 1 Zn_clus PF00172.18 ORY90311.1 - 0.02 15.0 7.3 0.033 14.3 7.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 ORY90312.1 - 1.7e-15 56.4 0.0 2.8e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY90312.1 - 0.0038 16.9 0.0 0.0073 15.9 0.0 1.4 1 0 0 1 1 1 1 Hfq protein Get5_C PF18514.1 ORY90312.1 - 0.0097 15.6 0.4 0.045 13.5 0.1 2.0 2 0 0 2 2 2 1 Get5 C-terminal domain Sec7 PF01369.20 ORY90313.1 - 1.5e-64 217.0 0.3 2.4e-64 216.4 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 ORY90313.1 - 3.8e-18 65.9 0.0 1e-15 58.0 0.0 3.3 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY90313.1 - 0.0069 16.2 1.2 1.9 8.4 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Atrophin-1 PF03154.15 ORY90313.1 - 0.039 12.3 15.8 0.08 11.2 15.8 1.4 1 0 0 1 1 1 0 Atrophin-1 family AP_endonuc_2 PF01261.24 ORY90314.1 - 8.4e-39 133.2 0.0 6.2e-26 91.1 0.0 2.8 2 1 1 3 3 3 2 Xylose isomerase-like TIM barrel Peptidase_M41 PF01434.18 ORY90315.1 - 1.1e-63 214.6 0.0 1.8e-63 213.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORY90315.1 - 1e-41 142.4 0.0 2.1e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 ORY90315.1 - 1.6e-13 51.0 0.4 6e-13 49.1 0.4 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_lid_3 PF17862.1 ORY90315.1 - 1.8e-11 43.7 0.1 4e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain TIP49 PF06068.13 ORY90315.1 - 0.0043 16.3 0.1 0.0072 15.6 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 ORY90315.1 - 0.0043 16.8 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY90315.1 - 0.005 17.2 0.3 0.11 12.9 0.2 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY90315.1 - 0.0055 16.7 0.0 0.019 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY90315.1 - 0.031 14.6 0.0 0.86 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY90315.1 - 0.048 13.4 0.0 0.15 11.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.6 ORY90315.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORY90315.1 - 0.096 12.8 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) EB1 PF03271.17 ORY90316.1 - 5.6e-13 48.9 2.2 1.3e-12 47.8 2.2 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORY90316.1 - 5.5e-07 29.7 0.8 5.5e-07 29.7 0.8 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 ORY90316.1 - 0.0035 16.0 0.1 0.005 15.4 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like CH_2 PF06294.11 ORY90316.1 - 0.013 15.6 0.6 0.023 14.8 0.6 1.5 1 0 0 1 1 1 0 CH-like domain in sperm protein Sporozoite_P67 PF05642.11 ORY90316.1 - 0.043 11.9 0.0 0.048 11.7 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SUIM_assoc PF16619.5 ORY90316.1 - 0.099 12.7 0.4 0.27 11.3 0.4 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 His_Phos_1 PF00300.22 ORY90317.1 - 1.8e-26 93.0 0.0 2.5e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LigB PF02900.18 ORY90317.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 2 0 0 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase PF00069.25 ORY90318.1 - 5.6e-45 153.8 0.0 1.4e-43 149.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90318.1 - 7.5e-17 61.5 0.0 1.1e-14 54.3 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY90318.1 - 1.6e-06 27.7 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY90318.1 - 0.0002 20.2 0.1 0.00042 19.2 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY90318.1 - 0.0039 17.1 0.3 0.0089 16.0 0.3 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY90318.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Carb_kinase PF01256.17 ORY90318.1 - 0.081 12.4 0.0 0.52 9.8 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate kinase RIO1 PF01163.22 ORY90318.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-PolyVal PF18762.1 ORY90318.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Haspin_kinase PF12330.8 ORY90318.1 - 0.28 10.1 0.0 0.28 10.1 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain adh_short_C2 PF13561.6 ORY90319.1 - 6.6e-49 166.6 0.2 8.3e-49 166.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY90319.1 - 6.2e-36 123.7 0.1 1.1e-35 122.9 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY90319.1 - 4.2e-05 23.5 2.0 0.0001 22.3 2.0 1.6 1 1 0 1 1 1 1 KR domain CS PF04969.16 ORY90320.1 - 2.8e-18 66.7 0.3 6.6e-18 65.5 0.1 1.7 2 0 0 2 2 2 1 CS domain DUF1344 PF07076.11 ORY90320.1 - 0.092 12.7 1.0 0.51 10.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) DUF4404 PF14357.6 ORY90320.1 - 0.11 13.1 3.8 6.5 7.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Mito_carr PF00153.27 ORY90321.1 - 1.3e-13 50.6 0.1 1.8e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein DUF952 PF06108.12 ORY90321.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF952) MFS_1 PF07690.16 ORY90322.1 - 2e-06 27.0 17.0 2e-06 27.0 17.0 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Podoplanin PF05808.11 ORY90322.1 - 1.8 8.7 3.8 8.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Podoplanin Glyoxal_oxid_N PF07250.11 ORY90613.1 - 3.9e-37 127.7 0.1 6.4e-36 123.8 0.1 2.7 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY90613.1 - 6.4e-23 80.9 0.1 1.3e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 ORY90613.1 - 0.013 15.5 0.3 0.55 10.3 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 ORY90614.1 - 6.5e-37 127.0 0.1 4.3e-34 117.8 0.1 3.7 2 2 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 ORY90614.1 - 9.2e-21 73.9 0.1 2.3e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.6 ORY90614.1 - 0.00099 19.1 0.5 0.14 12.2 0.0 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY90614.1 - 0.098 12.7 0.1 57 3.9 0.0 3.8 3 0 0 3 3 3 0 Kelch motif F-box-like PF12937.7 ORY90615.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 ORY90615.1 - 0.046 13.7 0.1 0.058 13.4 0.1 1.5 1 1 0 1 1 1 0 F-box-like domain PB1 PF00564.24 ORY90617.1 - 1.5e-09 37.7 0.0 3e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain MCM PF00493.23 ORY90619.1 - 8.5e-103 342.3 0.2 1.4e-102 341.5 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY90619.1 - 1.6e-38 131.4 0.3 3e-38 130.5 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY90619.1 - 3.4e-25 88.3 0.3 9.1e-25 86.9 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 ORY90619.1 - 4.5e-25 88.0 0.9 1.3e-24 86.5 0.9 1.9 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 ORY90619.1 - 2.6e-23 82.6 0.4 9.3e-23 80.8 0.4 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY90619.1 - 2.3e-07 30.4 0.0 1.7e-06 27.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY90619.1 - 0.00096 19.0 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY90619.1 - 0.0033 17.2 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 ORY90619.1 - 0.0062 16.5 0.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Tir_receptor_M PF03549.14 ORY90619.1 - 0.015 15.6 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) intimin-binding domain Chisel PF15355.6 ORY90619.1 - 0.23 11.7 0.9 0.61 10.3 0.9 1.7 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel SUR7 PF06687.12 ORY90620.1 - 4.1e-12 46.2 14.4 8.4e-12 45.2 14.5 1.4 1 1 0 1 1 1 1 SUR7/PalI family TNFR_16_TM PF18422.1 ORY90620.1 - 6.4 6.8 7.5 1.5 8.8 1.7 2.5 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain MBOAT PF03062.19 ORY90622.1 - 2.5e-43 148.8 0.2 4.8e-43 147.8 0.2 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Abhydrolase_1 PF00561.20 ORY90623.1 - 1.6e-10 41.1 0.0 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY90623.1 - 2.9e-09 36.5 0.0 4.5e-08 32.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY90623.1 - 4.4e-06 27.5 0.0 6.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ORY90623.1 - 0.0017 17.1 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family DLH PF01738.18 ORY90623.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Rotamase_3 PF13616.6 ORY90624.1 - 4.6e-16 59.4 0.0 8.9e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ORY90624.1 - 9.6e-13 48.9 0.0 2.1e-12 47.9 0.0 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ORY90624.1 - 0.014 16.2 0.0 0.018 15.9 0.0 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain Tyr-DNA_phospho PF06087.12 ORY90626.1 - 3.6e-49 167.8 0.0 5.5e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 ORY90626.1 - 0.075 12.9 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 PLD-like domain TrbI PF03743.14 ORY90626.1 - 0.1 12.4 0.4 0.19 11.6 0.4 1.3 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein UIM PF02809.20 ORY90626.1 - 1.2 9.2 5.0 0.2 11.7 0.3 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif MFS_1 PF07690.16 ORY90627.1 - 1.4e-44 152.5 44.2 1.1e-43 149.6 44.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY90627.1 - 6.9e-14 51.2 18.9 7.1e-14 51.1 18.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF872 PF05915.12 ORY90627.1 - 1.5 9.0 7.1 28 4.9 0.1 3.2 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) O-FucT PF10250.9 ORY90628.1 - 4.6e-08 33.1 0.1 1.4e-06 28.2 0.3 2.5 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase SUZ PF12752.7 ORY90628.1 - 3.1 8.6 6.8 5.1 7.9 0.7 3.2 3 0 0 3 3 3 0 SUZ domain Ribonuclease_3 PF00636.26 ORY90629.1 - 1.1e-33 116.0 0.0 9.2e-16 58.4 0.0 3.0 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 ORY90629.1 - 5.5e-20 71.3 0.0 1.6e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 ORY90629.1 - 4.1e-19 69.0 0.1 1.6e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ribonucleas_3_3 PF14622.6 ORY90629.1 - 9.8e-17 61.3 0.1 1.1e-09 38.5 0.3 3.6 2 1 0 2 2 2 2 Ribonuclease-III-like Helicase_C PF00271.31 ORY90629.1 - 8.3e-15 55.1 0.0 2.5e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY90629.1 - 9.2e-14 51.8 0.0 3.2e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ORY90629.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 ORY90629.1 - 0.019 14.2 0.0 0.055 12.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SecA_DEAD PF07517.14 ORY90629.1 - 0.047 13.0 0.3 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain dsrm PF00035.26 ORY90629.1 - 0.15 12.8 0.2 32 5.3 0.0 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif Bin3 PF06859.12 ORY90630.1 - 3.7e-31 107.9 0.0 5.5e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 ORY90630.1 - 7.3e-12 45.8 0.0 2.1e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY90630.1 - 2.3e-11 43.8 0.0 3.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY90630.1 - 7.8e-09 36.1 0.0 1.6e-08 35.0 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY90630.1 - 9.1e-09 35.3 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY90630.1 - 5.6e-08 33.4 0.0 1.1e-07 32.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY90630.1 - 3.4e-05 23.4 0.0 0.00013 21.6 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORY90630.1 - 0.0013 18.1 0.0 0.0023 17.3 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 ORY90630.1 - 0.0013 18.1 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ORY90630.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 ORY90630.1 - 0.002 17.8 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 ORY90630.1 - 0.0026 17.4 0.0 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Nodulation protein S (NodS) PrmA PF06325.13 ORY90630.1 - 0.0063 15.9 0.0 0.0094 15.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 ORY90630.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HIT PF01230.23 ORY90632.1 - 1.9e-25 89.5 0.0 3.4e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 ORY90632.1 - 1.2e-07 32.2 0.0 1.9e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 ORY90632.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Pkinase PF00069.25 ORY90634.1 - 9.5e-68 228.4 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90634.1 - 5.8e-46 156.9 0.0 8.2e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY90634.1 - 1.8e-07 30.8 0.0 1.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORY90634.1 - 0.009 14.8 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 ORY90634.1 - 0.012 14.7 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 ORY90634.1 - 0.041 13.5 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY90634.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Epimerase PF01370.21 ORY90635.1 - 8.6e-17 61.4 0.0 1.8e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY90635.1 - 2.7e-13 50.2 0.2 4.7e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY90635.1 - 6.2e-11 41.8 0.0 8.8e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY90635.1 - 1.8e-07 30.9 0.6 1.3e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY90635.1 - 3e-06 26.6 0.5 9.5e-05 21.7 0.5 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 ORY90635.1 - 0.00023 20.7 0.5 0.0024 17.4 0.6 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 ORY90635.1 - 0.0016 17.7 0.3 0.0022 17.2 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY90635.1 - 0.0032 16.6 1.2 0.17 10.9 0.1 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 ORY90635.1 - 0.0065 16.0 0.7 0.011 15.3 0.7 1.4 1 0 0 1 1 1 1 NmrA-like family PLAC8 PF04749.17 ORY90636.1 - 1.9e-16 60.9 4.1 2.5e-16 60.5 4.1 1.2 1 0 0 1 1 1 1 PLAC8 family SnoaL_4 PF13577.6 ORY90637.1 - 0.0019 18.3 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 ORY90637.1 - 0.027 15.1 0.0 0.036 14.7 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain FMO-like PF00743.19 ORY90638.1 - 9.4e-24 83.7 0.1 5.9e-23 81.1 0.1 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY90638.1 - 2e-17 63.3 0.2 6.5e-15 55.1 0.2 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY90638.1 - 2.4e-17 63.2 2.1 1.4e-14 54.1 1.9 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY90638.1 - 1.1e-10 41.6 1.4 3.4e-07 30.4 0.1 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY90638.1 - 1.4e-09 37.6 0.4 2.2e-08 33.6 0.0 2.6 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 ORY90638.1 - 6.5e-08 32.5 1.5 5.7e-05 22.9 0.3 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY90638.1 - 2.2e-06 27.3 3.4 0.00025 20.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY90638.1 - 5.5e-06 25.8 0.3 0.024 13.9 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ORY90638.1 - 8.9e-06 26.2 7.5 0.0035 17.9 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY90638.1 - 4.9e-05 23.4 1.3 0.026 14.5 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY90638.1 - 8.5e-05 21.8 8.0 0.0058 15.8 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain Shikimate_DH PF01488.20 ORY90638.1 - 0.00014 21.9 0.3 0.0073 16.4 0.0 2.9 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 ORY90638.1 - 0.00024 20.6 0.2 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase GIDA PF01134.22 ORY90638.1 - 0.00045 19.4 3.7 0.09 11.8 0.6 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 ORY90638.1 - 0.00054 18.8 7.2 0.14 10.9 1.9 2.3 2 0 0 2 2 2 2 HI0933-like protein 3HCDH_N PF02737.18 ORY90638.1 - 0.0013 18.7 2.0 0.019 14.8 0.3 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY90638.1 - 0.014 14.8 0.2 1.1 8.6 0.0 3.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY90638.1 - 0.027 14.9 2.3 0.5 10.8 0.9 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 ORY90638.1 - 0.029 13.4 0.3 5.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 ORY90638.1 - 0.061 13.3 1.0 2.4 8.1 0.2 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 ORY90638.1 - 0.11 11.8 5.1 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.17 ORY90638.1 - 0.35 11.5 1.8 12 6.6 0.4 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.19 ORY90638.1 - 0.59 9.3 1.8 19 4.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain PBP_N PF17093.5 ORY90639.1 - 0.25 11.6 5.7 0.53 10.5 5.7 1.5 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus DnaJ PF00226.31 ORY90640.1 - 5e-17 61.8 0.2 9.1e-17 60.9 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Arylsulfotran_2 PF14269.6 ORY90641.1 - 2.6e-51 174.8 1.3 3.7e-51 174.3 1.3 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 ORY90641.1 - 9.6e-08 31.3 0.2 3.3e-06 26.3 0.2 2.4 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Aldedh PF00171.22 ORY90643.1 - 8.5e-93 311.4 0.0 1e-92 311.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family MFS_1 PF07690.16 ORY90644.1 - 4.4e-43 147.6 29.0 4.4e-43 147.6 29.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY90644.1 - 1.1e-12 47.5 13.4 1.1e-12 47.5 13.4 2.9 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY90644.1 - 1.2e-05 24.0 3.0 1.2e-05 24.0 3.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UPF0182 PF03699.13 ORY90644.1 - 4.5 5.3 4.7 0.53 8.4 0.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) PP2C PF00481.21 ORY90645.1 - 2.6e-26 92.8 0.0 2e-18 67.0 0.0 3.0 3 0 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.6 ORY90645.1 - 0.0055 16.4 0.0 0.018 14.7 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C RRN3 PF05327.11 ORY90646.1 - 4.7e-181 603.1 0.0 2e-180 601.1 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 YL1 PF05764.13 ORY90646.1 - 2.5 8.2 16.9 0.056 13.5 2.8 2.3 2 0 0 2 2 2 0 YL1 nuclear protein F-box-like PF12937.7 ORY90647.1 - 8.2e-07 28.8 0.8 5.2e-05 23.0 0.1 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 ORY90647.1 - 0.00025 20.8 3.3 0.01 15.7 0.1 3.4 3 0 0 3 3 3 2 F-box domain MARVEL PF01284.23 ORY90648.1 - 0.044 13.8 9.8 0.067 13.2 9.8 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF4233 PF14017.6 ORY90648.1 - 0.2 12.0 7.9 1.6 9.1 2.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) DUF4870 PF09685.10 ORY90648.1 - 2.1 8.5 10.2 0.35 11.0 2.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4870) Protoglobin PF11563.8 ORY90649.1 - 6.7e-36 123.6 0.0 7.8e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Protoglobin F-box-like PF12937.7 ORY90652.1 - 3.2e-05 23.7 0.1 5.2e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY90652.1 - 0.014 15.2 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 F-box domain zf-CCHC PF00098.23 ORY90653.1 - 1.3e-27 94.6 47.2 1.1e-06 28.5 3.9 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_6 PF15288.6 ORY90653.1 - 4.9e-05 23.1 0.9 4.9e-05 23.1 0.9 5.3 4 1 1 5 5 5 2 Zinc knuckle zf-CCHC_3 PF13917.6 ORY90653.1 - 0.00012 22.0 26.0 0.12 12.3 1.6 5.3 3 2 2 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 ORY90653.1 - 0.00053 19.7 30.8 0.075 12.8 0.7 5.9 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 ORY90653.1 - 4.1 7.2 30.0 2 8.2 1.7 6.2 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger Band_7 PF01145.25 ORY90654.1 - 2.3e-28 99.4 2.2 3.3e-28 98.9 2.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORY90654.1 - 0.02 14.6 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family AcetylCoA_hydro PF02550.15 ORY90655.1 - 8.1e-44 150.0 0.0 1.3e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 ORY90655.1 - 4.4e-38 130.6 0.0 7.8e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 ORY90655.1 - 0.17 11.3 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Coenzyme A transferase Acetyltransf_3 PF13302.7 ORY90656.1 - 1.2e-07 32.5 0.0 1.5e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY90656.1 - 2.1e-05 24.8 0.0 0.00064 19.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY90656.1 - 0.00019 21.8 0.0 0.00036 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY90656.1 - 0.061 13.3 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Polyketide_cyc PF03364.20 ORY90657.1 - 6.2e-15 55.6 0.1 8.8e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 ORY90657.1 - 0.00021 21.6 0.2 0.0011 19.3 0.2 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MCRA PF06100.11 ORY90657.1 - 0.087 11.6 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 MCRA family TPR_2 PF07719.17 ORY90658.1 - 0.00021 21.1 1.0 0.0086 16.1 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY90658.1 - 0.00098 18.9 0.2 0.025 14.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ApoLp-III PF07464.11 ORY90658.1 - 0.073 13.2 1.0 0.14 12.3 1.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Glucosamine_iso PF01182.20 ORY90659.1 - 8.6e-65 218.8 0.0 9.7e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MFS_1 PF07690.16 ORY90660.1 - 5.9e-41 140.6 49.7 9.7e-41 139.9 46.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY90660.1 - 1.5e-12 46.7 27.7 2.4e-12 46.1 27.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY90660.1 - 4.5e-07 29.1 9.4 4.5e-07 29.1 9.4 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter Epimerase PF01370.21 ORY90661.1 - 1.5e-14 54.1 0.0 2e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY90661.1 - 1.1e-11 45.0 0.1 1.9e-11 44.2 0.1 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY90661.1 - 1e-10 41.1 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY90661.1 - 2.7e-10 39.8 1.2 1.1e-08 34.6 1.2 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY90661.1 - 3e-07 30.2 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY90661.1 - 0.00029 20.5 0.4 0.00041 20.0 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY90661.1 - 0.0042 16.3 0.1 0.0062 15.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY90661.1 - 0.013 14.6 0.2 0.078 12.1 0.2 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 ORY90661.1 - 0.019 14.4 0.0 0.066 12.7 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase AlgF PF11182.8 ORY90661.1 - 0.13 12.1 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Alginate O-acetyl transferase AlgF Nitroreductase PF00881.24 ORY90662.1 - 2e-16 60.5 0.0 2.3e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family eIF-3_zeta PF05091.12 ORY90663.1 - 1.9e-214 713.4 0.0 2.4e-214 713.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 ORY90663.1 - 0.11 12.0 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Glyco_tranf_2_4 PF13704.6 ORY90664.1 - 1e-09 38.8 0.1 2.1e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 ORY90664.1 - 1.9e-08 34.3 0.1 3e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Tyr-DNA_phospho PF06087.12 ORY90666.1 - 2e-12 46.8 0.0 3.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Prenylcys_lyase PF07156.14 ORY90666.1 - 0.0023 17.1 0.0 0.0059 15.7 0.0 1.6 2 0 0 2 2 2 1 Prenylcysteine lyase RXT2_N PF08595.11 ORY90666.1 - 0.044 13.8 0.4 0.044 13.8 0.4 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal Adaptin_N PF01602.20 ORY90667.1 - 1.6e-131 439.4 6.4 1.9e-131 439.2 6.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 ORY90667.1 - 3.4e-42 143.2 0.0 9.2e-42 141.8 0.0 1.8 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 ORY90667.1 - 6.6e-17 61.8 0.0 1.2e-16 60.9 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT PF02985.22 ORY90667.1 - 0.023 14.9 0.1 2.7 8.5 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat RasGEF_N_2 PF14663.6 ORY90667.1 - 0.54 10.7 2.6 3.6 8.0 0.1 3.5 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEV_ORF1 PF02444.16 ORY90667.1 - 1.8 9.1 7.1 1.2e+02 3.2 5.7 3.1 3 0 0 3 3 3 0 Hepatitis E virus ORF-2 (Putative capsid protein) ECH_1 PF00378.20 ORY90668.1 - 3.3e-11 43.0 0.0 3.6e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY90668.1 - 0.014 14.9 0.0 0.015 14.8 0.0 1.0 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY90669.1 - 1.7e-56 191.3 0.0 2e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY90669.1 - 8.1e-30 104.4 0.0 1.9e-26 93.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase AMP-binding PF00501.28 ORY90670.1 - 2.1e-90 303.3 0.0 3e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY90670.1 - 4.2e-15 56.5 0.7 8.7e-15 55.5 0.7 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PB1 PF00564.24 ORY90671.1 - 2e-07 30.8 0.2 7e-07 29.1 0.1 1.9 2 0 0 2 2 2 1 PB1 domain Presenilin PF01080.17 ORY90671.1 - 9.1 4.9 7.0 12 4.5 7.0 1.1 1 0 0 1 1 1 0 Presenilin TRAPP PF04051.16 ORY90672.1 - 6.7e-31 107.0 0.0 7.9e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Bestrophin PF01062.21 ORY90673.1 - 8.5e-38 130.4 0.2 1.1e-18 67.7 0.0 2.3 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Gaa1 PF04114.14 ORY90673.1 - 0.16 11.0 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component RRM_1 PF00076.22 ORY90674.1 - 1.3e-34 117.8 0.0 5.9e-14 51.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY90674.1 - 3.8e-05 23.7 0.0 0.0053 16.8 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 ORY90674.1 - 0.0012 18.8 0.0 0.0051 16.8 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 ORY90674.1 - 0.0024 17.8 0.0 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif LisH PF08513.11 ORY90675.1 - 6.1e-06 26.0 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 LisH Abhydrolase_6 PF12697.7 ORY90676.1 - 4.3e-12 47.1 0.6 4.3e-12 47.1 0.6 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY90676.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PB1 PF00564.24 ORY90677.1 - 1.5e-08 34.5 0.0 6.2e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 PB1 domain CAF20 PF17052.5 ORY90677.1 - 0.68 10.1 5.3 1.2 9.2 5.3 1.5 1 0 0 1 1 1 0 Cap associated factor Aminotran_1_2 PF00155.21 ORY90678.1 - 2.7e-61 207.8 0.0 3.1e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY90678.1 - 9.8e-06 24.3 0.0 1.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 ORY90678.1 - 0.00048 19.6 0.0 0.001 18.5 0.0 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORY90678.1 - 0.00063 18.8 0.0 0.0033 16.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY90678.1 - 0.0025 17.1 0.0 0.0036 16.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Sec63 PF02889.16 ORY90679.1 - 8.2e-77 257.8 0.0 1.2e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 ORY90679.1 - 8.7e-30 103.8 0.0 8.5e-23 81.0 0.0 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 ORY90679.1 - 3.8e-14 53.0 0.0 1.4e-10 41.4 0.0 2.6 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY90679.1 - 9.1e-10 38.9 0.0 8.3e-05 22.9 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY90679.1 - 0.085 13.1 0.2 0.69 10.2 0.2 2.5 1 1 0 1 1 1 0 AAA domain Helicase_PWI PF18149.1 ORY90679.1 - 0.089 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal helicase PWI domain AAA_19 PF13245.6 ORY90679.1 - 0.17 12.2 0.3 16 5.8 0.3 2.8 2 1 0 2 2 2 0 AAA domain CoA_binding PF02629.19 ORY90681.1 - 2.9e-29 101.6 0.1 8e-29 100.2 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 ORY90681.1 - 5.7e-21 74.9 0.2 8.6e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 ORY90681.1 - 2.1e-08 34.1 0.0 5e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 ORY90681.1 - 1.8e-06 28.5 0.1 1.1e-05 25.8 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain GFO_IDH_MocA PF01408.22 ORY90681.1 - 0.005 17.7 0.0 0.015 16.1 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Peptidase_C14 PF00656.22 ORY90682.1 - 6.1e-51 173.8 0.0 8.8e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Caspase domain KCNQC3-Ank-G_bd PF11956.8 ORY90682.1 - 2.5 8.4 7.0 2.4 8.5 1.3 2.9 2 1 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 Peptidase_C14 PF00656.22 ORY90683.1 - 2.3e-63 214.4 0.0 2.8e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 ORY90683.1 - 0.3 11.1 1.9 0.46 10.4 0.0 2.3 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Pkinase PF00069.25 ORY90685.1 - 9.9e-73 244.7 0.0 1.3e-72 244.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90685.1 - 7.1e-36 123.8 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY90685.1 - 0.0024 17.3 0.8 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY90685.1 - 0.0031 16.5 0.0 0.018 14.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY90685.1 - 0.054 13.4 0.1 0.054 13.4 0.1 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY90685.1 - 0.082 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4834 PF16118.5 ORY90685.1 - 2 9.4 5.7 3.2 8.8 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) p450 PF00067.22 ORY90686.1 - 2.6e-09 36.4 0.0 0.0027 16.5 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 EIF_2_alpha PF07541.12 ORY90687.1 - 6.6e-36 122.9 0.0 1.2e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 ORY90687.1 - 6.1e-13 48.9 4.3 1e-12 48.2 1.8 2.3 2 0 0 2 2 2 1 S1 RNA binding domain Amidohydro_1 PF01979.20 ORY90687.1 - 0.0043 16.4 0.1 0.0064 15.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family SRP_SPB PF02978.19 ORY90687.1 - 0.038 14.6 2.1 0.27 11.9 2.1 2.1 1 1 0 1 1 1 0 Signal peptide binding domain MitMem_reg PF13012.6 ORY90688.1 - 4.5e-27 94.7 0.0 7.2e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY90688.1 - 4.8e-17 62.0 0.0 7.5e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UCH PF00443.29 ORY90689.1 - 9.5e-53 179.3 0.0 1.1e-52 179.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY90689.1 - 5.3e-22 78.8 0.0 9.2e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YgbA_NO PF11756.8 ORY90689.1 - 0.03 14.7 1.8 0.17 12.3 0.3 2.2 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter Actin_micro PF17003.5 ORY90689.1 - 0.15 11.2 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Putative actin-like family adh_short PF00106.25 ORY90690.1 - 9.1e-38 129.7 0.1 1.2e-37 129.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY90690.1 - 1.4e-29 103.3 0.3 1.7e-29 103.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY90690.1 - 7e-06 26.1 0.6 0.0001 22.2 0.6 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY90690.1 - 0.014 14.8 0.0 3.9 6.9 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Asp PF00026.23 ORY90691.1 - 4.4e-75 253.0 3.0 9.3e-75 252.0 3.0 1.6 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY90691.1 - 1.7e-10 41.5 19.7 3.1e-09 37.3 4.7 3.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY90691.1 - 2.2e-05 24.3 0.1 9.3e-05 22.3 0.0 2.1 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY90691.1 - 0.0013 19.3 1.5 2.2 9.0 0.0 3.3 2 1 0 2 2 2 2 Aspartyl protease Utp14 PF04615.13 ORY90691.1 - 0.015 13.9 8.1 0.02 13.5 8.1 1.1 1 0 0 1 1 1 0 Utp14 protein SOG2 PF10428.9 ORY90691.1 - 0.17 11.0 19.1 0.3 10.2 19.1 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein PAP1 PF08601.10 ORY90691.1 - 3.1 7.4 27.9 4.6 6.9 27.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Apt1 PF10351.9 ORY90691.1 - 3.6 6.3 10.8 4.8 5.9 10.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain VID27 PF08553.10 ORY90692.1 - 3e-165 549.6 0.0 1.1e-163 544.4 0.0 2.1 2 0 0 2 2 2 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 ORY90692.1 - 5.9e-35 120.7 6.4 5.2e-34 117.6 0.0 2.8 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 ORY90692.1 - 6.6e-16 58.6 0.0 2.2e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 VID27 PH-like domain CDC45 PF02724.14 ORY90692.1 - 0.43 8.8 12.6 0.86 7.8 12.6 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ORY90692.1 - 6.3 6.0 10.2 13 5.0 10.2 1.4 1 0 0 1 1 1 0 NOA36 protein SH3_9 PF14604.6 ORY90693.1 - 4.6e-14 52.0 0.0 1.6e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 ORY90693.1 - 4.9e-12 46.3 0.9 8e-12 45.6 0.1 1.8 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.28 ORY90693.1 - 1.3e-11 43.9 0.0 3.8e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY90693.1 - 2.1e-06 27.3 0.0 4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.17 ORY90693.1 - 2.2e-06 27.7 0.0 3.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY90693.1 - 4.9e-06 26.9 0.2 2.2e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) CH PF00307.31 ORY90693.1 - 2.4e-05 24.5 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain SAM_3 PF18016.1 ORY90693.1 - 0.057 13.2 0.5 0.31 10.9 0.0 2.5 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY90693.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain RhoGEF PF00621.20 ORY90694.1 - 6.8e-22 78.6 0.0 1.3e-13 51.6 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain MFS_1 PF07690.16 ORY90695.1 - 3.7e-25 88.6 27.0 3.7e-25 88.6 27.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ORY90696.1 - 3.9e-19 68.8 0.0 1.6e-18 66.7 0.1 2.0 2 1 0 2 2 2 1 Cytochrome P450 Nsp1_C PF05064.13 ORY90697.1 - 5.2e-29 100.4 0.0 1.3e-28 99.1 0.0 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 ORY90697.1 - 5.1e-06 27.2 73.2 0.00058 20.7 24.5 4.1 2 1 2 4 4 4 2 Nucleoporin FG repeat region Baculo_PEP_C PF04513.12 ORY90697.1 - 0.026 14.6 2.3 0.78 9.8 3.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PMC2NT PF08066.12 ORY90697.1 - 0.04 14.6 1.3 9.9 6.9 0.2 2.4 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF1664 PF07889.12 ORY90697.1 - 0.041 13.9 0.0 2.4 8.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 ORY90697.1 - 0.14 12.6 2.1 43 4.6 0.1 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) CSN5_C PF18323.1 ORY90697.1 - 0.38 11.7 1.8 0.69 10.9 1.0 1.8 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain Syntaxin-6_N PF09177.11 ORY90697.1 - 7.2 7.2 5.2 32 5.2 1.3 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Flavoprotein PF02441.19 ORY90698.1 - 6.5e-50 168.9 0.0 7.6e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Flavoprotein Lipase_3 PF01764.25 ORY90699.1 - 5.9e-17 61.8 0.0 5.5e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Hydrolase_4 PF12146.8 ORY90699.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Neur_chan_memb PF02932.16 ORY90701.1 - 2.9 7.9 4.8 3.7 7.5 4.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf_CCCH_4 PF18345.1 ORY90702.1 - 2.4e-06 27.4 6.5 4.3e-06 26.6 6.5 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 ORY90702.1 - 2.7e-06 27.0 3.4 4.7e-06 26.3 3.4 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 ORY90702.1 - 7.3e-05 22.6 2.9 0.00013 21.7 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 ORY90702.1 - 0.0056 17.1 3.6 0.0095 16.4 3.6 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY90702.1 - 0.056 14.1 0.2 0.086 13.5 0.2 1.2 1 0 0 1 1 1 0 Torus domain WD40 PF00400.32 ORY90703.1 - 2.8e-21 75.4 10.0 0.00025 21.8 0.0 6.8 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY90703.1 - 3e-12 46.7 0.0 2.1e-06 28.0 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY90703.1 - 0.0005 19.7 2.7 0.025 14.2 2.7 2.5 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 ORY90703.1 - 0.0023 17.8 0.8 0.046 13.7 0.0 3.3 3 1 1 4 4 4 1 PQQ enzyme repeat PQQ_3 PF13570.6 ORY90703.1 - 0.0087 16.5 5.4 11 6.7 0.5 5.2 5 1 0 5 5 5 1 PQQ-like domain DUF3138 PF11336.8 ORY90703.1 - 0.082 11.5 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) VID27 PF08553.10 ORY90703.1 - 0.18 10.8 0.0 0.67 9.0 0.0 1.9 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Mito_carr PF00153.27 ORY90706.1 - 3.3e-19 68.6 0.8 1.4e-08 34.5 0.0 5.0 5 0 0 5 5 5 4 Mitochondrial carrier protein Amidase PF01425.21 ORY90707.1 - 7.1e-89 298.8 0.0 8.5e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF836 PF05768.14 ORY90708.1 - 6.6e-10 39.3 0.0 8.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) PSP PF04046.16 ORY90709.1 - 8.9e-09 35.1 0.2 8.9e-09 35.1 0.2 2.9 3 0 0 3 3 3 1 PSP MFS_1 PF07690.16 ORY90710.1 - 4.5e-27 94.9 26.6 4.5e-27 94.9 26.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY90710.1 - 1.7e-10 40.4 1.4 1.7e-10 40.4 1.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 ORY90711.1 - 1.7e-71 241.4 0.0 2.2e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CPDase PF07823.11 ORY90712.1 - 6.6e-18 65.1 0.0 2.2e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 ORY90712.1 - 4.5e-05 23.4 0.4 0.00012 22.1 0.4 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily RIC1 PF07064.13 ORY90713.1 - 1.2e-103 345.9 0.2 1.6e-103 345.5 0.2 1.1 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 ORY90713.1 - 0.036 14.3 0.3 0.77 10.1 0.0 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 ORY90713.1 - 0.049 14.0 0.0 0.18 12.2 0.0 2.0 1 0 0 1 1 1 0 Kelch motif CENP-L PF13092.6 ORY90714.1 - 6.9e-13 49.1 2.2 5e-11 43.1 2.0 2.9 2 1 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 DOPA_dioxygen PF08883.11 ORY90715.1 - 3.7e-30 104.2 0.5 4.8e-30 103.9 0.1 1.4 2 0 0 2 2 2 1 Dopa 4,5-dioxygenase family AA_permease_2 PF13520.6 ORY90716.1 - 3.6e-14 52.4 13.8 3.9e-14 52.3 13.8 1.0 1 0 0 1 1 1 1 Amino acid permease DNA_pol3_chi PF04364.13 ORY90717.1 - 0.013 15.7 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC FMN_red PF03358.15 ORY90718.1 - 5.7e-27 94.4 0.0 8.2e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY90718.1 - 2e-06 27.7 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold RRM_1 PF00076.22 ORY90719.1 - 6.5e-49 163.6 0.0 4.7e-17 61.6 0.0 7.0 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_6 PF12697.7 ORY90720.1 - 0.0057 17.3 0.9 0.011 16.4 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY90720.1 - 0.12 12.0 0.0 0.48 10.0 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold F-box-like PF12937.7 ORY90721.1 - 0.0029 17.4 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY90721.1 - 0.0082 16.5 0.0 1.2 9.7 0.0 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Abhydrolase_6 PF12697.7 ORY90722.1 - 1.2e-06 29.3 1.2 1.6e-06 28.9 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY90722.1 - 2.6e-06 27.3 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ORY90722.1 - 0.00066 19.2 0.0 0.0016 18.0 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 ORY90722.1 - 0.0049 16.2 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 ORY90722.1 - 0.009 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.13 ORY90722.1 - 0.026 14.4 0.1 0.11 12.3 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 ORY90722.1 - 0.027 13.8 0.0 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 ORY90722.1 - 0.059 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme SLATT_1 PF18181.1 ORY90722.1 - 0.14 12.1 2.2 0.35 10.8 2.2 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 WD40 PF00400.32 ORY90723.1 - 7.3e-33 112.1 8.3 1.8e-06 28.5 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY90723.1 - 6e-13 48.9 0.0 2.6e-05 24.4 0.0 4.9 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY90723.1 - 0.0033 16.4 0.0 0.068 12.1 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 ORY90723.1 - 0.0034 17.0 0.2 1.8 8.1 0.0 2.5 2 1 0 2 2 2 2 PQQ-like domain WD40_like PF17005.5 ORY90723.1 - 0.0046 16.3 0.0 0.18 11.1 0.1 2.7 2 1 1 3 3 3 1 WD40-like domain PQQ_3 PF13570.6 ORY90723.1 - 0.024 15.1 1.8 3.6 8.2 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain BBS2_Mid PF14783.6 ORY90723.1 - 0.033 14.2 0.0 0.54 10.3 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 ORY90723.1 - 0.042 13.8 0.1 31 4.7 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat eIF2A PF08662.11 ORY90723.1 - 0.047 13.6 0.0 2 8.3 0.0 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Mito_carr PF00153.27 ORY90724.1 - 7.4e-55 182.9 3.9 1.1e-19 70.1 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Med3 PF11593.8 ORY90724.1 - 0.031 13.5 0.4 5.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal PrcB_C PF14343.6 ORY90724.1 - 0.17 12.0 0.5 3 8.1 0.1 2.8 3 0 0 3 3 3 0 PrcB C-terminal Red1 PF07964.11 ORY90725.1 - 0.081 11.2 12.4 0.12 10.6 12.4 1.1 1 0 0 1 1 1 0 Rec10 / Red1 FancD2 PF14631.6 ORY90725.1 - 6.6 4.0 9.3 11 3.2 9.3 1.3 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease E1-E2_ATPase PF00122.20 ORY90726.1 - 2.1e-22 79.5 0.8 3.9e-22 78.6 0.1 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY90726.1 - 2.5e-19 70.4 0.0 2.3e-12 47.7 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY90726.1 - 0.00084 19.4 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY90726.1 - 0.0072 16.1 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_3 PF07859.13 ORY90729.1 - 3.5e-45 154.5 0.3 8.7e-45 153.2 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold NAD_binding_8 PF13450.6 ORY90729.1 - 7.1e-10 39.0 0.0 2.4e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ORY90729.1 - 3.4e-09 35.7 0.0 3.8e-08 32.2 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY90729.1 - 3.8e-09 36.2 0.0 4.5e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Say1_Mug180 PF10340.9 ORY90729.1 - 8e-06 25.0 0.0 1.6e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase K_oxygenase PF13434.6 ORY90729.1 - 1.7e-05 24.1 0.0 0.34 10.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY90729.1 - 0.00012 21.4 0.0 0.039 13.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.28 ORY90729.1 - 0.00022 20.3 0.5 0.00088 18.3 0.2 2.2 2 1 0 2 2 2 1 Carboxylesterase family DAO PF01266.24 ORY90729.1 - 0.0003 20.5 0.1 0.021 14.4 0.0 3.0 2 2 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY90729.1 - 0.0013 18.0 0.2 0.0042 16.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ORY90729.1 - 0.0083 16.7 0.0 0.024 15.2 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_S9 PF00326.21 ORY90729.1 - 0.042 13.3 0.1 1.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family NAD_binding_9 PF13454.6 ORY90729.1 - 0.046 13.7 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Chlorophyllase2 PF12740.7 ORY90729.1 - 0.17 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme adh_short_C2 PF13561.6 ORY90730.1 - 2e-51 174.8 0.0 1.9e-29 102.9 0.6 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY90730.1 - 1.3e-40 139.0 0.1 1.9e-39 135.1 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY90730.1 - 4.7e-07 29.9 0.0 7.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF2688 PF10892.8 ORY90730.1 - 0.0083 15.6 0.2 0.047 13.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2688) p450 PF00067.22 ORY90731.1 - 1.4e-65 221.9 0.0 1.6e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 ORY90732.1 - 0.037 14.1 14.9 0.067 13.3 14.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 ORY90733.1 - 1.3e-31 109.8 34.7 1.6e-31 109.5 34.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_8 PF13450.6 ORY90734.1 - 1.6e-07 31.5 0.0 3.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 ORY90734.1 - 8.8e-07 27.7 0.1 2.3e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY90734.1 - 0.00024 20.5 0.0 0.0021 17.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY90734.1 - 0.0076 15.4 0.0 0.07 12.3 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORY90734.1 - 0.016 15.2 0.0 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY90734.1 - 0.18 11.1 0.1 18 4.5 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Oxidored_FMN PF00724.20 ORY90735.1 - 1.8e-60 205.0 0.0 2.4e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ABM PF03992.16 ORY90736.1 - 0.036 14.2 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase DUF4387 PF14330.6 ORY90736.1 - 0.041 14.6 0.0 0.052 14.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4387) adh_short_C2 PF13561.6 ORY90737.1 - 1.6e-52 178.4 0.4 2.3e-52 177.9 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY90737.1 - 1.9e-36 125.3 0.4 2.8e-36 124.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY90737.1 - 8.1e-05 22.6 1.3 0.00051 20.0 1.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY90737.1 - 0.00018 21.1 0.2 0.00074 19.1 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ORY90737.1 - 0.00046 20.1 0.2 0.0014 18.5 0.1 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 ORY90737.1 - 0.028 15.1 0.0 0.07 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF5427 PF10310.9 ORY90738.1 - 2.1e-52 178.6 38.2 6.5e-43 147.4 0.0 4.8 2 2 3 5 5 5 4 Family of unknown function (DUF5427) zf-RING_UBOX PF13445.6 ORY90741.1 - 4.4e-07 29.8 5.4 1.2e-06 28.4 5.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY90741.1 - 1.3e-05 24.9 7.9 1.3e-05 24.9 7.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY90741.1 - 1.6e-05 24.6 6.2 1.6e-05 24.6 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY90741.1 - 2e-05 24.8 7.8 2e-05 24.8 7.8 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 ORY90741.1 - 4.6e-05 23.5 8.6 0.00012 22.2 8.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY90741.1 - 0.00037 20.4 6.5 0.00037 20.4 6.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 ORY90741.1 - 0.0027 17.6 3.4 0.0027 17.6 3.4 2.8 2 1 1 3 3 3 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 ORY90741.1 - 0.014 15.3 7.7 0.045 13.6 7.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY90741.1 - 0.015 15.1 8.8 0.015 15.1 8.8 2.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 ORY90741.1 - 0.017 15.3 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 U-box domain Ogr_Delta PF04606.12 ORY90741.1 - 0.026 14.5 2.6 0.028 14.4 0.2 2.4 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.6 ORY90741.1 - 0.92 10.5 4.0 28 5.9 1.2 3.7 2 1 0 2 2 2 0 C2H2-type zinc finger DUF1644 PF07800.12 ORY90741.1 - 1.1 9.3 13.9 0.082 13.0 5.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) FlhC PF05280.11 ORY90741.1 - 1.2 8.8 3.8 0.57 9.9 1.1 1.7 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) zf-Di19 PF05605.12 ORY90741.1 - 1.8 8.9 10.3 2 8.7 2.6 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Sina PF03145.16 ORY90741.1 - 2.2 8.2 11.9 0.044 13.7 3.3 2.4 2 1 0 2 2 2 0 Seven in absentia protein family MMR_HSR1_Xtn PF16897.5 ORY90742.1 - 1e-40 138.0 0.2 4.4e-40 136.0 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORY90742.1 - 5.1e-20 71.7 0.0 9.8e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 ORY90742.1 - 5.9e-18 64.7 0.0 1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ORY90742.1 - 3.9e-10 39.5 0.0 7.6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY90742.1 - 0.023 14.8 0.4 10 6.2 0.2 2.5 1 1 1 2 2 2 0 Dynamin family AAA_28 PF13521.6 ORY90742.1 - 0.03 14.6 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 ORY90742.1 - 0.049 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORY90742.1 - 0.071 13.4 0.0 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY90742.1 - 0.14 12.4 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pro_isomerase PF00160.21 ORY90743.1 - 1.1e-35 123.2 0.0 1.6e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORY90743.1 - 1.1e-15 57.2 0.1 2e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5102 PF17104.5 ORY90744.1 - 1.6e-62 212.1 1.6 9.9e-62 209.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) FEZ PF07763.13 ORY90744.1 - 0.25 11.1 3.6 3.8 7.2 0.0 3.1 3 0 0 3 3 3 0 FEZ-like protein STE3 PF02076.15 ORY90745.1 - 0.013 14.8 0.2 0.033 13.4 0.1 1.6 1 1 1 2 2 2 0 Pheromone A receptor ABC2_membrane_3 PF12698.7 ORY90745.1 - 0.058 12.5 0.2 1.8 7.6 0.1 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein CDC27 PF09507.10 ORY90746.1 - 6.9 5.9 11.2 8.8 5.6 11.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Na_Ca_ex PF01699.24 ORY90747.1 - 0.038 14.0 1.1 0.038 14.0 1.1 2.9 3 1 0 3 3 3 0 Sodium/calcium exchanger protein GDPD PF03009.17 ORY90748.1 - 9.3e-30 104.2 0.0 1.3e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 ORY90748.1 - 0.0025 18.2 0.2 0.0083 16.5 0.2 1.9 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.16 ORY90749.1 - 3.1e-35 121.8 24.7 3.1e-35 121.8 24.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4672 PF15716.5 ORY90749.1 - 0.23 11.1 0.6 0.37 10.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) SNF2_N PF00176.23 ORY90750.1 - 5e-63 212.9 0.1 8.3e-63 212.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY90750.1 - 4.4e-20 72.1 0.0 1.4e-18 67.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 ORY90750.1 - 5e-14 52.4 1.0 2.9e-13 49.9 1.0 2.5 1 0 0 1 1 1 1 HSA ResIII PF04851.15 ORY90750.1 - 3.2e-11 43.5 0.0 8.2e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY90750.1 - 0.00013 21.8 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase UPF0231 PF06062.11 ORY90750.1 - 0.0084 16.4 7.8 0.0084 16.4 7.8 3.1 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0231) Rhomboid PF01694.22 ORY90751.1 - 0.00034 20.6 4.6 0.00062 19.8 4.6 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 ORY90751.1 - 0.034 14.7 1.9 0.087 13.4 0.2 2.3 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) E3_UbLigase_EDD PF11547.8 ORY90751.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD MMR_HSR1 PF01926.23 ORY90752.1 - 9e-13 48.3 0.0 3.5e-12 46.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY90752.1 - 4e-07 30.1 0.0 1.5e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 ORY90752.1 - 0.00032 20.2 0.0 0.0049 16.4 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 ORY90752.1 - 0.00041 19.5 0.0 0.00063 18.9 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Med3 PF11593.8 ORY90752.1 - 0.27 10.4 2.0 0.39 9.8 2.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Isy1 PF06246.12 ORY90753.1 - 2.2e-94 315.8 1.6 2.5e-94 315.6 1.6 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF4769 PF15992.5 ORY90753.1 - 0.0069 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4769) RRP14 PF15459.6 ORY90753.1 - 0.98 10.1 3.7 0.8 10.3 0.5 2.3 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Sas10_Utp3 PF04000.15 ORY90754.1 - 6.3e-15 55.6 2.0 7.3e-15 55.4 0.7 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family CDV3 PF15359.6 ORY90754.1 - 0.2 12.1 1.4 0.25 11.8 0.2 1.8 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Ribosomal_S13 PF00416.22 ORY90755.1 - 1.1e-18 67.9 0.0 2.4e-10 40.9 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein S13/S18 Sugar_tr PF00083.24 ORY90756.1 - 8.1e-68 229.3 19.5 9.7e-68 229.1 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY90756.1 - 9.2e-27 93.9 25.5 9.2e-27 93.9 25.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily GFO_IDH_MocA PF01408.22 ORY90757.1 - 4e-27 95.4 0.3 6.6e-27 94.7 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORY90757.1 - 6.1e-05 23.7 0.3 0.0001 22.9 0.3 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY90757.1 - 0.0037 17.8 0.1 0.01 16.4 0.0 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 ORY90757.1 - 0.015 15.8 0.1 0.033 14.6 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.16 ORY90758.1 - 1.3e-22 80.2 22.7 2e-22 79.6 22.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.6 ORY90758.1 - 0.03 14.3 0.7 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) DUF5336 PF17270.2 ORY90758.1 - 0.083 12.5 0.4 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5336) GFO_IDH_MocA PF01408.22 ORY90759.1 - 1.3e-18 68.0 0.0 1.9e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 ORY90759.1 - 0.061 14.0 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 ORY90760.1 - 9.9e-65 218.3 0.0 2.6e-64 217.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY90760.1 - 3.8e-48 164.5 0.0 7.3e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY90760.1 - 1.4e-21 76.4 0.1 2.8e-21 75.4 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 ORY90760.1 - 2.4e-07 30.7 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.6 ORY90760.1 - 0.0095 16.3 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Zn_clus PF00172.18 ORY90761.1 - 8.5e-06 25.8 1.5 1.7e-05 24.8 1.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY90761.1 - 0.053 12.5 0.2 0.089 11.8 0.2 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Dickkopf_N PF04706.12 ORY90761.1 - 0.55 10.7 2.4 1.2 9.7 2.4 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Ribosomal_L13 PF00572.18 ORY90762.1 - 4.4e-53 178.8 0.0 5.9e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Metallophos PF00149.28 ORY90763.1 - 6.5e-39 134.6 0.2 8.9e-39 134.1 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY90763.1 - 0.0024 18.3 0.8 0.005 17.3 0.8 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TAD2 PF18521.1 ORY90763.1 - 0.14 12.1 0.8 0.39 10.8 0.8 1.7 1 0 0 1 1 1 0 Transactivation domain 2 Methyltransf_25 PF13649.6 ORY90764.1 - 9.5e-13 48.7 0.0 1.9e-08 34.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORY90764.1 - 7.1e-12 45.5 0.0 1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY90764.1 - 2e-11 44.5 0.0 7.3e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY90764.1 - 1.6e-09 37.7 0.0 1.9e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY90764.1 - 1.7e-08 35.0 0.0 0.00014 22.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 ORY90764.1 - 6.8e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY90764.1 - 0.014 14.9 0.0 0.053 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 ORY90764.1 - 0.02 14.2 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain NodS PF05401.11 ORY90764.1 - 0.053 13.1 0.0 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) FtsJ PF01728.19 ORY90764.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.8 2 1 0 2 2 2 0 FtsJ-like methyltransferase NNMT_PNMT_TEMT PF01234.17 ORY90764.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Citrate_synt PF00285.21 ORY90765.1 - 2.8e-124 414.8 0.0 3.3e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Fox-1_C PF12414.8 ORY90765.1 - 0.43 11.0 2.6 1.6 9.2 0.2 2.6 2 0 0 2 2 2 0 Calcitonin gene-related peptide regulator C terminal DUF4149 PF13664.6 ORY90766.1 - 1e-23 83.6 0.4 1e-23 83.6 0.4 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) CytB6-F_Fe-S PF08802.10 ORY90766.1 - 2.1 8.4 0.0 2.1 8.4 0.0 2.9 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Sulfotransfer_4 PF17784.1 ORY90767.1 - 7.7e-52 176.2 0.1 1.4e-51 175.4 0.1 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY90767.1 - 4.8e-06 27.1 0.6 0.0002 21.8 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family PolyA_pol PF01743.20 ORY90769.1 - 2e-22 80.0 0.0 3.7e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ORY90769.1 - 4.7e-05 23.1 0.2 0.00013 21.7 0.2 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Romo1 PF10247.9 ORY90770.1 - 2.8e-23 82.0 10.8 3.2e-23 81.9 10.8 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 BUD22 PF09073.10 ORY90771.1 - 0.13 11.5 8.7 0.18 11.1 8.7 1.2 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 ORY90771.1 - 0.77 9.4 9.4 1.2 8.8 8.4 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3827 PF12877.7 ORY90771.1 - 2 6.7 9.6 2.9 6.2 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) RRN3 PF05327.11 ORY90771.1 - 2 6.9 4.3 3 6.3 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Macoilin PF09726.9 ORY90771.1 - 2.4 6.6 4.9 2.6 6.5 4.9 1.1 1 0 0 1 1 1 0 Macoilin family Taxilin PF09728.9 ORY90773.1 - 0.36 10.0 15.7 0.72 9.0 15.7 1.4 1 0 0 1 1 1 0 Myosin-like coiled-coil protein EzrA PF06160.12 ORY90773.1 - 0.64 8.1 10.9 4.9 5.2 10.6 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Flagellin_C PF00700.21 ORY90773.1 - 0.97 9.8 5.2 3.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region GAS PF13851.6 ORY90773.1 - 6.1 6.1 20.7 1.4 8.2 12.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding RPA43_OB PF17875.1 ORY90774.1 - 3e-24 86.0 2.4 3e-24 86.0 2.4 4.3 4 1 0 4 4 4 1 RPA43 OB domain in RNA Pol I WBS_methylT PF12589.8 ORY90775.1 - 4e-19 69.2 4.3 6.2e-19 68.5 4.3 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 ORY90775.1 - 1.2e-09 38.7 0.0 3.7e-09 37.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY90775.1 - 9e-08 32.7 0.0 2.4e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY90775.1 - 0.0015 19.2 0.1 0.0078 16.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY90775.1 - 0.013 15.3 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORY90775.1 - 0.046 13.5 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FANCI_S4 PF14678.6 ORY90775.1 - 0.13 11.4 0.0 0.93 8.6 0.0 1.9 2 0 0 2 2 2 0 FANCI solenoid 4 AdoMet_MTase PF07757.13 ORY90775.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Myosin_head PF00063.21 ORY90776.1 - 2.4e-46 158.3 0.0 4.5e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) CREPT PF16566.5 ORY90776.1 - 0.44 10.7 25.7 0.39 10.9 7.4 2.5 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SAB PF04382.13 ORY90776.1 - 1.4 9.0 5.6 0.29 11.2 0.3 2.5 3 0 0 3 3 3 0 SAB domain Occludin_ELL PF07303.13 ORY90776.1 - 6.3 7.6 15.8 5.2 7.9 4.8 3.0 2 1 1 3 3 3 0 Occludin homology domain Snf7 PF03357.21 ORY90777.1 - 1e-40 139.2 11.4 1.2e-40 139.0 11.4 1.0 1 0 0 1 1 1 1 Snf7 CCDC24 PF15669.5 ORY90777.1 - 0.031 14.1 2.1 0.056 13.3 2.1 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 24 family TauD PF02668.16 ORY90778.1 - 2.3e-44 152.2 0.4 2.9e-44 151.9 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pirin PF02678.16 ORY90779.1 - 1.7e-29 102.0 0.6 2.6e-29 101.3 0.6 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 ORY90779.1 - 7.2e-06 25.6 2.0 2.1e-05 24.2 0.4 2.2 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 ORY90779.1 - 0.00011 22.3 0.2 0.0077 16.4 0.1 3.0 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain MFS_1 PF07690.16 ORY90780.1 - 4.2e-14 52.2 11.0 4.2e-14 52.2 11.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.8 ORY90780.1 - 5.8e-05 21.9 5.5 0.0016 17.2 4.7 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like DUF4500 PF14937.6 ORY90780.1 - 0.14 12.2 0.8 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) TauD PF02668.16 ORY90781.1 - 5.4e-48 164.1 0.2 6.9e-48 163.8 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 ORY90782.1 - 8e-24 84.2 18.7 8e-24 84.2 18.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M10 PF00413.24 ORY90782.1 - 0.055 13.3 0.0 0.078 12.8 0.0 1.4 1 1 0 1 1 1 0 Matrixin DUF1127 PF06568.11 ORY90782.1 - 0.061 13.1 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Pirin PF02678.16 ORY90783.1 - 1.7e-29 101.9 0.6 2.7e-29 101.3 0.6 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 ORY90783.1 - 7.2e-06 25.6 2.0 2.1e-05 24.2 0.4 2.2 2 0 0 2 2 2 1 Cupin domain Pirin_C_2 PF17954.1 ORY90783.1 - 0.00011 22.3 0.2 0.0077 16.4 0.1 3.0 2 1 0 2 2 2 1 Quercetinase C-terminal cupin domain CLN3 PF02487.17 ORY90784.1 - 3e-117 392.1 0.4 3.5e-117 391.9 0.4 1.0 1 0 0 1 1 1 1 CLN3 protein COQ7 PF03232.13 ORY90785.1 - 5.1e-72 241.2 0.1 6.2e-72 240.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Ferritin PF00210.24 ORY90785.1 - 0.022 14.7 0.4 0.35 10.8 0.1 2.1 2 0 0 2 2 2 0 Ferritin-like domain Rubrerythrin PF02915.17 ORY90785.1 - 0.077 13.4 0.0 0.25 11.8 0.0 1.8 1 1 1 2 2 2 0 Rubrerythrin Sugar_tr PF00083.24 ORY90786.1 - 4.6e-66 223.5 25.0 5.5e-66 223.3 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY90786.1 - 7.3e-26 90.9 25.1 7.3e-26 90.9 25.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2269 PF10027.9 ORY90786.1 - 0.083 12.9 5.6 0.25 11.4 1.6 2.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) AAA PF00004.29 ORY90787.1 - 5.1e-18 65.8 0.0 1.4e-17 64.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY90787.1 - 0.00014 22.1 0.8 0.0057 16.9 0.2 2.7 1 1 1 2 2 2 1 AAA domain Vps36_ESCRT-II PF11605.8 ORY90787.1 - 0.0057 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 AAA_30 PF13604.6 ORY90787.1 - 0.0084 15.8 1.0 0.028 14.2 0.3 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY90787.1 - 0.012 15.6 0.0 0.039 13.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY90787.1 - 0.019 15.4 0.7 0.019 15.4 0.7 2.6 2 1 1 3 3 3 0 AAA ATPase domain Pox_Ag35 PF03286.14 ORY90787.1 - 0.35 10.6 13.7 0.93 9.3 8.7 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Hep_59 PF07052.11 ORY90788.1 - 3.5e-32 111.3 3.1 9.9e-32 109.9 3.1 1.8 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 DUF2140 PF09911.9 ORY90788.1 - 0.055 13.0 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Acyl-CoA_dh_N PF02771.16 ORY90789.1 - 2.9e-27 95.6 0.0 6e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY90789.1 - 2.4e-26 92.8 0.0 4.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY90789.1 - 1.8e-19 69.7 0.0 4.1e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY90789.1 - 1.5e-09 38.2 0.0 3.5e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY90789.1 - 0.039 13.6 0.0 0.23 11.1 0.0 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PAPS_reduct PF01507.19 ORY90790.1 - 4.5e-40 137.5 0.0 6.3e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CHCH PF06747.13 ORY90791.1 - 2.5e-08 33.8 11.2 4.6e-07 29.8 5.7 2.4 2 0 0 2 2 2 2 CHCH domain CX9C PF16860.5 ORY90791.1 - 0.0021 18.0 9.1 0.21 11.6 2.3 2.8 2 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PBP_GOBP PF01395.22 ORY90791.1 - 0.014 15.6 0.3 0.014 15.6 0.3 1.6 2 0 0 2 2 2 0 PBP/GOBP family COX6B PF02297.17 ORY90791.1 - 0.8 10.0 11.9 0.1 12.8 4.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 ORY90791.1 - 0.93 9.6 12.4 0.97 9.5 4.9 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 ORY90791.1 - 4.2 7.7 10.7 12 6.3 0.4 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 UreF PF01730.16 ORY90793.1 - 3.4e-22 79.4 4.2 5.1e-22 78.9 4.2 1.2 1 0 0 1 1 1 1 UreF F-box-like PF12937.7 ORY90794.1 - 0.00061 19.6 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like S-antigen PF05756.11 ORY90794.1 - 0.1 13.0 0.2 0.1 13.0 0.2 2.0 2 0 0 2 2 2 0 S-antigen protein CLTH PF10607.9 ORY90795.1 - 2e-33 115.4 0.0 2.4e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Patatin PF01734.22 ORY90797.1 - 6.1e-09 36.3 0.2 6.1e-09 36.3 0.2 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase SMC_N PF02463.19 ORY90798.1 - 7.2e-21 74.6 0.0 1.7e-20 73.5 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY90798.1 - 3.4e-12 46.7 1.3 9.2e-10 38.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORY90798.1 - 7.7e-10 39.6 20.1 7.7e-10 39.6 20.1 5.2 2 2 0 3 3 3 1 AAA domain SMC_hinge PF06470.13 ORY90798.1 - 0.0011 19.3 0.0 0.0036 17.6 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 ORY90798.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY90798.1 - 0.002 18.0 0.7 0.002 18.0 0.7 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FCH PF00611.23 ORY90798.1 - 2.6 8.4 11.1 1.4 9.3 2.1 3.0 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Peptidase_M48_N PF16491.5 ORY90799.1 - 0.17 11.8 1.6 0.34 10.8 1.6 1.4 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices Abhydrolase_4 PF08386.10 ORY90800.1 - 8.6e-21 74.0 0.0 2.4e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 ORY90800.1 - 1.8e-17 63.9 0.1 2.2e-13 50.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY90800.1 - 0.0032 16.8 0.0 0.45 9.7 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Thioredoxin PF00085.20 ORY90801.1 - 1.9e-22 79.2 0.0 2.3e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY90801.1 - 3e-06 27.7 0.1 4.7e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY90801.1 - 0.00012 22.4 0.0 0.0034 17.7 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like TraF PF13728.6 ORY90801.1 - 0.0019 18.1 0.0 0.0022 17.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ORY90801.1 - 0.0053 16.5 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 ORY90801.1 - 0.035 14.3 0.0 0.055 13.7 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like KaiB PF07689.12 ORY90801.1 - 0.084 12.6 0.1 0.17 11.7 0.1 1.5 1 1 0 1 1 1 0 KaiB domain Thioredoxin_3 PF13192.6 ORY90801.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain XPG_I PF00867.18 ORY90802.1 - 1.9e-06 28.1 0.0 7.7e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 ORY90802.1 - 0.019 15.4 0.1 0.076 13.5 0.0 1.8 2 0 0 2 2 2 0 XPG N-terminal domain RsdA_SigD_bd PF16751.5 ORY90802.1 - 0.058 13.7 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Aconitase PF00330.20 ORY90804.1 - 3.6e-111 372.4 0.1 2.4e-110 369.7 0.1 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY90804.1 - 1.9e-18 67.1 0.0 3.8e-18 66.1 0.0 1.5 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ORY90804.1 - 0.015 14.1 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) MCM PF00493.23 ORY90804.1 - 0.21 10.7 0.1 0.36 9.9 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain LRR_4 PF12799.7 ORY90805.1 - 0.0031 17.9 0.3 6.9 7.2 0.1 3.2 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Con-6 PF10346.9 ORY90807.1 - 6.1e-08 32.6 0.7 1.5e-07 31.3 0.7 1.7 1 0 0 1 1 1 1 Conidiation protein 6 SH3_9 PF14604.6 ORY90808.1 - 7.7e-16 57.7 0.0 1.3e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY90808.1 - 4.9e-15 54.9 0.0 8.5e-15 54.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY90808.1 - 3.3e-10 39.5 0.0 5.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CAP_N PF01213.19 ORY90808.1 - 3.1 7.2 9.2 1.3 8.4 1.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TIM21 PF08294.11 ORY90809.1 - 6.6e-23 81.2 0.0 1.3e-21 77.0 0.0 2.1 2 0 0 2 2 2 1 TIM21 CAP_N PF01213.19 ORY90809.1 - 0.27 10.7 8.5 1.4 8.3 1.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 ORY90809.1 - 2.7 8.0 7.0 12 5.8 1.3 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator BLM10_mid PF16507.5 ORY90810.1 - 2.4e-182 607.3 0.0 4e-182 606.5 0.0 1.4 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 ORY90810.1 - 7.7e-16 57.8 3.0 1.8e-14 53.4 0.0 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 ORY90810.1 - 2.2e-08 33.7 0.7 0.0015 18.6 0.2 5.3 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 ORY90810.1 - 5.3e-05 23.5 2.1 0.0061 16.9 0.1 5.0 7 0 0 7 7 7 1 HEAT repeats Arm PF00514.23 ORY90810.1 - 0.00012 22.0 0.0 0.0019 18.2 0.0 3.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY90810.1 - 0.00027 21.3 0.7 0.013 15.9 0.2 4.1 2 1 1 3 3 3 1 HEAT-like repeat BLM10_N PF16547.5 ORY90810.1 - 0.00097 19.4 0.1 0.0023 18.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal Tudor-knot PF11717.8 ORY90810.1 - 0.032 14.1 0.4 0.075 12.9 0.4 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Adaptin_N PF01602.20 ORY90810.1 - 0.15 10.5 0.1 0.44 9.0 0.0 1.7 2 0 0 2 2 2 0 Adaptin N terminal region PNK3P PF08645.11 ORY90811.1 - 1.4e-51 174.4 0.0 2e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Hydrolase PF00702.26 ORY90811.1 - 0.002 18.4 0.0 0.72 10.1 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY90811.1 - 0.0027 17.8 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY90811.1 - 0.22 11.9 0.2 2.3 8.6 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Dicty_REP PF05086.12 ORY90811.1 - 7 4.5 7.1 8.5 4.2 7.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pex24p PF06398.11 ORY90814.1 - 2.2e-06 26.9 3.2 2.2e-06 26.9 3.2 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Sgf11 PF08209.11 ORY90815.1 - 4.5e-12 45.3 0.1 7.7e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) GIT_SHD PF08518.11 ORY90815.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT MFS_1 PF07690.16 ORY90816.1 - 2.2e-32 112.4 28.5 2.2e-32 112.4 28.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Oxidored_q3 PF00499.20 ORY90816.1 - 0.26 11.0 6.3 0.13 12.0 2.8 2.4 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MIP PF00230.20 ORY90817.1 - 1.8e-43 148.9 17.7 2.6e-43 148.4 17.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein Glyco_hydro_47 PF01532.20 ORY90819.1 - 9e-115 384.2 0.0 1.2e-114 383.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Chorismate_bind PF00425.18 ORY90820.1 - 6.9e-86 288.0 0.0 9.6e-86 287.5 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 ORY90820.1 - 7.6e-29 100.8 0.0 1.3e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY90820.1 - 4e-07 30.0 0.0 1.3e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 ORY90820.1 - 1.6e-06 28.4 0.0 4e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Pkinase PF00069.25 ORY90822.1 - 4.5e-63 213.1 0.0 7e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY90822.1 - 1.2e-32 113.2 0.0 5.2e-27 94.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY90822.1 - 3.3e-05 23.4 0.0 0.0096 15.3 0.0 3.0 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 ORY90822.1 - 0.0035 16.4 0.0 0.0064 15.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 ORY90822.1 - 0.01 15.8 0.0 0.01 15.8 0.0 2.7 3 1 0 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY90822.1 - 0.078 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Con-6 PF10346.9 ORY90823.1 - 3.9e-09 36.4 0.7 5.8e-09 35.8 0.7 1.2 1 0 0 1 1 1 1 Conidiation protein 6 CdiI_4 PF18624.1 ORY90824.1 - 0.078 13.5 0.3 0.15 12.5 0.3 1.4 1 0 0 1 1 1 0 CDI immunity protein F-box-like PF12937.7 ORY90825.1 - 0.028 14.3 0.5 0.044 13.7 0.5 1.3 1 0 0 1 1 1 0 F-box-like DEAD PF00270.29 ORY90826.1 - 2.4e-46 157.7 0.0 3.5e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY90826.1 - 1.4e-24 86.5 0.0 3.4e-23 82.1 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY90826.1 - 1.4e-17 63.6 0.2 2.7e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY90826.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY90827.1 - 8.4e-22 77.4 0.1 3.5e-15 55.6 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 ORY90827.1 - 1.3e-16 60.9 0.0 5.5e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 ORY90827.1 - 2.6e-05 24.5 0.0 6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IBR PF01485.21 ORY90827.1 - 0.19 12.0 5.0 1.7 8.9 4.4 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain p450 PF00067.22 ORY90828.1 - 7.1e-44 150.3 0.0 9e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LPD13 PF18825.1 ORY90828.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 AAA PF00004.29 ORY90829.1 - 1.8e-41 141.7 0.0 3e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY90829.1 - 5e-26 90.5 0.1 1.8e-25 88.7 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ORY90829.1 - 5.9e-23 80.7 3.4 1.5e-22 79.4 3.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ORY90829.1 - 1.2e-08 34.6 0.1 3.1e-07 30.1 0.0 2.8 3 0 0 3 3 3 1 AAA+ lid domain AAA_16 PF13191.6 ORY90829.1 - 1e-05 26.0 0.1 0.00017 22.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY90829.1 - 5.1e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY90829.1 - 9.1e-05 22.8 0.4 0.008 16.5 0.1 2.7 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 ORY90829.1 - 9.3e-05 22.2 0.0 0.00019 21.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 ORY90829.1 - 0.00012 22.4 0.6 0.0099 16.3 0.0 3.4 4 0 0 4 4 4 1 RNA helicase TIP49 PF06068.13 ORY90829.1 - 0.00013 21.3 0.0 0.00031 20.0 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 ORY90829.1 - 0.00017 21.8 0.0 0.0035 17.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY90829.1 - 0.00037 20.5 0.0 0.001 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ORY90829.1 - 0.00046 19.4 0.0 0.00096 18.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 ORY90829.1 - 0.00081 19.4 0.0 0.0022 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY90829.1 - 0.0012 19.4 0.0 0.003 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY90829.1 - 0.0038 17.3 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORY90829.1 - 0.0041 16.9 0.1 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY90829.1 - 0.015 15.7 0.1 0.048 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 ORY90829.1 - 0.026 14.0 0.3 0.14 11.7 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 ORY90829.1 - 0.029 13.9 0.1 0.8 9.2 0.1 2.5 2 1 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 ORY90829.1 - 0.041 13.3 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY90829.1 - 0.046 13.6 0.0 0.26 11.2 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 ORY90829.1 - 0.058 13.1 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY90829.1 - 0.068 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 ORY90829.1 - 0.096 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 ORY90829.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 ORY90829.1 - 0.12 12.3 0.0 1.4 8.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea RhoGAP PF00620.27 ORY90831.1 - 4.2e-38 130.5 2.3 9.4e-38 129.4 0.0 2.6 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 ORY90831.1 - 0.00067 19.9 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Gly_transf_sug PF04488.15 ORY90832.1 - 1.3e-05 25.7 0.0 2.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Exo5 PF09810.9 ORY90833.1 - 1e-60 206.2 0.0 5.5e-58 197.2 0.0 3.0 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease UIM PF02809.20 ORY90833.1 - 7.2e-07 28.7 11.3 0.00049 19.8 3.4 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif PDDEXK_1 PF12705.7 ORY90833.1 - 0.0095 15.9 0.1 0.62 9.9 0.0 3.2 4 0 0 4 4 4 1 PD-(D/E)XK nuclease superfamily PEP-utilisers_N PF05524.13 ORY90833.1 - 0.023 14.9 2.8 0.06 13.5 2.8 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal RAP80_UIM PF18282.1 ORY90833.1 - 2.1 8.2 6.3 2 8.2 2.3 2.5 1 1 1 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Abhydrolase_3 PF07859.13 ORY90834.1 - 2.7e-13 50.2 0.0 3.3e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY90834.1 - 9.1e-05 21.5 0.0 0.05 12.5 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 ORY90834.1 - 0.00013 21.3 0.0 0.016 14.5 0.0 2.7 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY90834.1 - 0.00018 22.2 0.1 0.00025 21.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ORY90834.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 ORY90834.1 - 0.13 12.0 0.0 1.9 8.3 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 ORY90834.1 - 0.17 11.3 0.0 5.1 6.5 0.0 2.7 3 0 0 3 3 3 0 Esterase PHB depolymerase UPF0121 PF03661.13 ORY90835.1 - 6.9e-48 163.2 2.7 7.6e-48 163.0 2.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) zf-MYND PF01753.18 ORY90836.1 - 1.4e-10 41.0 12.9 1.4e-10 41.0 12.9 2.2 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 ORY90836.1 - 2.4 8.5 14.9 1.9 8.8 12.1 2.3 2 1 1 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 ORY90836.1 - 2.9 7.8 10.3 18 5.3 10.3 2.3 1 1 0 1 1 1 0 HIT zinc finger DUF3512 PF12024.8 ORY90837.1 - 0.00012 21.7 2.3 0.00022 20.8 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) Viral_helicase1 PF01443.18 ORY90837.1 - 0.21 11.3 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase L51_S25_CI-B8 PF05047.16 ORY90838.1 - 1.2e-09 37.9 0.7 3.5e-09 36.4 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain F-box-like PF12937.7 ORY90839.1 - 1.9e-06 27.6 0.0 0.00012 21.9 0.0 2.7 2 0 0 2 2 2 1 F-box-like Cupin_1 PF00190.22 ORY90839.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Cupin F-box-like PF12937.7 ORY90840.1 - 1.6e-06 27.9 0.0 7.1e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like Ysc84 PF04366.12 ORY90841.1 - 1.7e-36 124.8 2.5 3.5e-36 123.8 2.5 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORY90841.1 - 8.2e-18 63.7 0.7 3.1e-17 61.9 0.1 2.3 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 ORY90841.1 - 4e-13 49.0 0.3 1.4e-11 44.1 0.0 2.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 ORY90841.1 - 1.3e-10 40.8 0.1 6.4e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain WD40 PF00400.32 ORY90842.1 - 3.6e-11 43.4 11.6 0.013 16.3 0.5 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat PRELI PF04707.14 ORY90843.1 - 3.8e-29 101.5 0.0 2.5e-19 69.6 0.0 3.6 4 0 0 4 4 4 3 PRELI-like family Ras PF00071.22 ORY90845.1 - 1.4e-52 177.6 0.0 1.6e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY90845.1 - 1.3e-19 70.6 0.0 1.9e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY90845.1 - 2.7e-07 30.2 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY90845.1 - 1.3e-05 24.9 0.1 0.00025 20.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY90845.1 - 7.2e-05 22.8 0.1 0.034 14.0 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 ORY90845.1 - 0.00047 19.7 0.0 0.0032 17.0 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORY90845.1 - 0.0021 18.1 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 ORY90845.1 - 0.036 13.6 0.0 0.081 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORY90845.1 - 0.044 13.8 0.1 0.2 11.7 0.1 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORY90845.1 - 0.062 13.7 0.1 0.13 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Glucan_synthase PF02364.15 ORY90846.1 - 0 1229.6 5.4 6e-262 871.5 0.0 2.2 2 0 0 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 ORY90846.1 - 4.8e-42 143.3 0.1 1.2e-41 142.0 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 LRR_4 PF12799.7 ORY90847.1 - 3.7e-07 30.4 11.8 0.78 10.2 1.1 5.7 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY90847.1 - 0.00028 20.7 0.0 0.0012 18.7 0.0 2.1 2 1 0 2 2 2 1 F-box-like LRR_6 PF13516.6 ORY90847.1 - 0.00075 19.4 16.1 8 6.8 0.1 7.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 ORY90847.1 - 0.0071 16.1 14.0 3.3 7.5 1.2 5.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 ORY90847.1 - 8.3 7.4 21.7 2e+02 3.2 1.8 7.5 7 2 0 7 7 7 0 Leucine Rich Repeat Rad51 PF08423.11 ORY90848.1 - 1.1e-09 37.9 0.0 5.1e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Rad51 DnaB_C PF03796.15 ORY90848.1 - 0.00063 19.2 0.0 0.0014 18.0 0.0 1.5 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 ORY90848.1 - 0.0018 17.9 0.0 0.0073 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY90848.1 - 0.0039 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 KaiC Terminase_6 PF03237.15 ORY90848.1 - 0.049 13.3 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Terminase-like family GvpD PF07088.11 ORY90848.1 - 0.075 11.6 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein RecA PF00154.21 ORY90848.1 - 0.084 12.3 0.0 1.3 8.4 0.0 2.1 1 1 1 2 2 2 0 recA bacterial DNA recombination protein PHO4 PF01384.20 ORY90849.1 - 2.3e-112 375.4 18.0 2.7e-112 375.1 18.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family SprT-like PF10263.9 ORY90850.1 - 3.4e-25 88.1 0.1 6e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.19 ORY90850.1 - 0.14 12.6 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box Polyoma_coat2 PF00761.20 ORY90850.1 - 1.3 8.6 3.7 0.51 10.0 0.3 1.8 2 0 0 2 2 2 0 Polyomavirus coat protein Oxidored-like PF09791.9 ORY90851.1 - 2.4e-07 30.3 6.9 4e-07 29.6 6.9 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal PAC1 PF16094.5 ORY90851.1 - 7.6 5.6 6.5 11 5.1 6.5 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 SNF2_N PF00176.23 ORY90852.1 - 7.2e-56 189.4 0.0 1e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY90852.1 - 2e-19 70.0 0.0 4.3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY90852.1 - 5.3e-10 38.9 0.0 1.5e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORY90852.1 - 6.2e-05 23.1 0.0 0.00018 21.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.24 ORY90852.1 - 0.0011 18.8 0.2 0.006 16.5 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.6 ORY90852.1 - 0.0011 18.6 4.2 0.062 12.9 0.1 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD PF00628.29 ORY90852.1 - 0.0011 18.8 11.0 0.019 14.9 1.9 3.2 3 0 0 3 3 3 2 PHD-finger Rpr2 PF04032.16 ORY90852.1 - 0.017 15.4 0.5 0.061 13.6 0.5 1.9 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PHD_4 PF16866.5 ORY90852.1 - 0.026 14.6 6.7 1.7 8.8 0.0 4.3 4 0 0 4 4 4 0 PHD-finger Zf_RING PF16744.5 ORY90852.1 - 2.8 8.1 4.5 7 6.9 0.0 3.0 3 0 0 3 3 3 0 KIAA1045 RING finger Rhomboid PF01694.22 ORY90853.1 - 6.7e-31 107.3 10.2 6.7e-31 107.3 10.2 2.0 2 1 0 2 2 2 1 Rhomboid family zf-MYND PF01753.18 ORY90854.1 - 9.7e-11 41.6 11.8 2.4e-10 40.3 11.8 1.7 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY90854.1 - 0.071 13.4 12.7 0.26 11.6 9.0 2.6 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Nramp PF01566.18 ORY90855.1 - 1.9e-82 277.1 21.6 3.1e-47 161.3 3.3 2.4 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein SUI1 PF01253.22 ORY90856.1 - 3.7e-22 78.6 0.1 7.4e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Flu_B_NS1 PF02942.14 ORY90856.1 - 0.021 13.9 0.1 0.029 13.5 0.1 1.1 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) SnoaL_2 PF12680.7 ORY90857.1 - 1.5e-06 28.7 0.2 1.9e-06 28.5 0.2 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY90857.1 - 0.00055 19.7 1.5 0.013 15.3 1.5 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Phage_T7_tail PF03906.14 ORY90857.1 - 0.0065 16.2 0.0 0.0069 16.1 0.0 1.1 1 0 0 1 1 1 1 Phage T7 tail fibre protein Invas_SpaK PF03519.14 ORY90857.1 - 0.0072 16.4 0.0 0.0082 16.2 0.0 1.2 1 0 0 1 1 1 1 Invasion protein B family Phage_sheath_1N PF17481.2 ORY90857.1 - 0.016 15.7 0.1 0.017 15.6 0.1 1.1 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain DUF1674 PF07896.12 ORY90858.1 - 1.1e-17 64.3 0.8 1.1e-17 64.3 0.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1674) HATPase_c PF02518.26 ORY90859.1 - 8.4e-19 68.1 0.0 1.5e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY90859.1 - 4.2e-14 52.7 0.0 9.2e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 ORY90859.1 - 2.7e-09 36.9 0.0 7.2e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.6 ORY90859.1 - 0.00059 20.2 0.0 5.9 7.2 0.0 3.9 4 0 0 4 4 4 2 GAF domain HATPase_c_3 PF13589.6 ORY90859.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase XPA_C PF05181.12 ORY90860.1 - 3.7e-24 84.4 3.6 3.7e-24 84.4 1.7 2.1 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 ORY90860.1 - 0.013 15.6 2.6 0.022 14.8 0.2 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Zn-ribbon_8 PF09723.10 ORY90860.1 - 0.17 12.0 1.6 20 5.4 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Vma12 PF11712.8 ORY90860.1 - 0.3 11.2 1.5 9.4 6.3 0.3 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4510 PF14971.6 ORY90860.1 - 0.85 10.0 6.4 9 6.6 0.5 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4510) Desulfoferrod_N PF06397.12 ORY90860.1 - 1.4 8.6 4.6 6.2 6.5 0.9 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF2387 PF09526.10 ORY90860.1 - 2.4 8.3 5.1 2.6 8.3 0.6 3.0 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) SnoaL_2 PF12680.7 ORY90861.1 - 0.00012 22.7 0.0 0.00014 22.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY90861.1 - 0.02 14.7 0.0 0.29 10.9 0.0 2.0 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 ORY90862.1 - 3.1e-05 24.5 0.0 3.9e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY90862.1 - 0.0024 17.7 0.5 0.063 13.1 0.5 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Invas_SpaK PF03519.14 ORY90862.1 - 0.016 15.3 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Invasion protein B family Phage_sheath_1N PF17481.2 ORY90862.1 - 0.017 15.6 0.1 0.022 15.2 0.1 1.1 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain ATP-synt_F PF01990.17 ORY90863.1 - 3.7e-31 107.3 0.1 4.2e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit ATP-grasp_2 PF08442.10 ORY90864.1 - 1.9e-69 233.3 0.1 3.5e-69 232.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ORY90864.1 - 4.7e-22 78.4 1.5 9.9e-22 77.4 1.5 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 ORY90864.1 - 6e-07 29.1 0.8 2e-06 27.5 0.1 2.2 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 ORY90864.1 - 4.1e-05 23.4 0.1 0.0021 17.8 0.0 2.6 1 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DWNN PF08783.11 ORY90865.1 - 2.4e-30 104.6 0.0 5.3e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 ORY90865.1 - 1.7e-09 37.3 5.6 3.7e-09 36.2 5.6 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 ORY90865.1 - 1.2e-05 25.1 1.8 2.2e-05 24.3 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 ORY90865.1 - 2.2e-05 24.3 0.9 6.3e-05 22.9 0.9 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_3 PF13920.6 ORY90865.1 - 2.5e-05 24.0 8.0 2.5e-05 24.0 8.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY90865.1 - 0.00011 22.0 11.9 0.00011 22.0 11.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY90865.1 - 0.011 16.0 10.3 0.011 16.0 10.3 1.6 2 0 0 2 2 1 0 Ring finger domain zf-RING_5 PF14634.6 ORY90865.1 - 0.014 15.3 8.9 0.014 15.3 8.9 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.6 ORY90865.1 - 0.03 14.1 9.6 0.063 13.1 9.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 ORY90865.1 - 0.04 13.8 11.2 0.079 12.8 11.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ku_C PF03730.14 ORY90865.1 - 0.083 13.6 9.1 0.31 11.8 9.1 2.0 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm zf-CCHC_5 PF14787.6 ORY90865.1 - 0.14 11.9 2.7 0.17 11.6 0.5 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger CDC45 PF02724.14 ORY90865.1 - 0.22 9.8 7.6 0.3 9.3 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C3HC4_4 PF15227.6 ORY90865.1 - 0.42 10.8 12.1 0.94 9.7 12.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc-ribbons_6 PF07191.12 ORY90865.1 - 1.3 9.1 11.8 1.2 9.2 7.6 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-RING_UBOX PF13445.6 ORY90865.1 - 7.9 6.6 10.3 17 5.5 10.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Choline_kinase PF01633.20 ORY90866.1 - 3.1e-49 167.5 0.1 6.4e-25 88.0 0.0 3.1 3 1 0 3 3 3 2 Choline/ethanolamine kinase APH PF01636.23 ORY90866.1 - 1.8e-07 31.3 1.9 4.4e-06 26.8 1.9 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family CENP-B_dimeris PF09026.10 ORY90866.1 - 0.41 11.0 11.6 0.1 13.0 5.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cnd3 PF12719.7 ORY90867.1 - 2.9e-80 269.6 0.5 2.9e-80 269.6 0.5 3.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 ORY90867.1 - 6.4e-09 36.1 6.3 0.0059 16.7 0.0 5.1 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY90867.1 - 1.7e-05 25.1 7.0 3.1e-05 24.3 2.0 5.2 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.22 ORY90867.1 - 0.00072 19.6 7.1 1.2 9.6 0.1 5.0 5 0 0 5 5 5 2 HEAT repeat UNC45-central PF11701.8 ORY90867.1 - 0.012 15.6 1.2 12 5.8 0.0 4.5 5 1 0 5 5 5 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 ORY90867.1 - 0.057 13.0 0.1 1.5 8.3 0.1 2.6 2 0 0 2 2 2 0 CLASP N terminal RTP1_C1 PF10363.9 ORY90867.1 - 0.32 11.2 2.2 1.9 8.7 0.3 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RXT2_N PF08595.11 ORY90867.1 - 2.4 8.2 20.2 1 9.4 0.2 3.4 3 0 0 3 3 3 0 RXT2-like, N-terminal HEAT_EZ PF13513.6 ORY90867.1 - 3.4 8.3 13.7 43 4.8 0.0 6.1 5 1 0 5 5 5 0 HEAT-like repeat RNA_pol_3_Rpc31 PF11705.8 ORY90867.1 - 8.9 6.5 30.1 3.1 8.0 14.9 3.4 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 NmrA PF05368.13 ORY90868.1 - 2.3e-23 83.0 0.0 3.5e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY90868.1 - 9.7e-10 38.6 0.0 1.5e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding AAA_6 PF12774.7 ORY90871.1 - 4.5e-132 440.0 0.0 1.6e-131 438.2 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 ORY90871.1 - 1.8e-122 409.8 5.0 1.8e-122 409.8 5.0 3.9 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 ORY90871.1 - 6.1e-117 391.1 7.3 6.1e-117 391.1 7.3 4.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 ORY90871.1 - 2.5e-69 232.8 6.0 4.5e-69 231.9 0.0 4.2 4 1 1 5 5 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY90871.1 - 3.1e-64 216.8 0.0 6.6e-64 215.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 ORY90871.1 - 4.2e-43 147.7 6.2 8.2e-43 146.7 6.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 ORY90871.1 - 6.5e-42 143.1 0.0 4.7e-36 124.0 0.0 4.9 5 0 0 5 5 5 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY90871.1 - 6e-33 114.0 0.0 1.4e-32 112.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 ORY90871.1 - 3.5e-29 101.3 0.0 3.8e-27 94.7 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 ORY90871.1 - 3.8e-28 98.2 0.0 1e-10 41.8 0.0 6.4 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 ORY90871.1 - 4.6e-20 72.0 0.0 1.9e-19 70.0 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 ORY90871.1 - 3.5e-13 50.1 0.0 0.0055 17.1 0.0 5.5 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY90871.1 - 3.5e-12 46.8 2.8 0.019 15.2 0.0 7.0 7 0 0 7 7 6 2 AAA domain AAA_33 PF13671.6 ORY90871.1 - 6.6e-08 32.8 4.4 0.31 11.2 0.0 5.5 5 1 1 6 6 5 2 AAA domain AAA_18 PF13238.6 ORY90871.1 - 1.1e-07 32.5 0.7 0.033 14.7 0.0 5.5 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 ORY90871.1 - 2.6e-07 31.2 9.9 0.76 10.1 0.0 8.6 9 0 0 9 9 6 1 AAA ATPase domain T2SSE PF00437.20 ORY90871.1 - 5.9e-05 22.3 0.0 0.032 13.3 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 ORY90871.1 - 0.00035 20.0 0.3 2.4 7.5 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 ORY90871.1 - 0.00035 20.7 0.6 0.0025 18.0 0.0 2.7 2 0 0 2 2 2 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 ORY90871.1 - 0.0012 18.2 0.0 0.4 10.0 0.0 3.8 4 0 0 4 4 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.17 ORY90871.1 - 0.0013 18.5 0.1 0.16 11.7 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_29 PF13555.6 ORY90871.1 - 0.0044 16.7 0.0 0.96 9.2 0.0 3.7 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY90871.1 - 0.01 15.4 0.6 0.76 9.3 0.0 3.6 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 ORY90871.1 - 0.018 15.4 4.6 1.4 9.2 0.0 4.8 5 0 0 5 5 5 0 AAA domain Rad17 PF03215.15 ORY90871.1 - 0.02 14.8 0.1 5.4 6.9 0.0 3.9 5 0 0 5 5 4 0 Rad17 P-loop domain AAA_24 PF13479.6 ORY90871.1 - 0.031 14.0 0.0 50 3.5 0.0 4.0 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 ORY90871.1 - 0.11 12.3 0.0 2.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 ORY90871.1 - 0.22 12.0 2.1 9.5 6.7 0.0 3.8 4 0 0 4 4 2 0 ABC transporter UPF0242 PF06785.11 ORY90871.1 - 6.7 6.8 13.1 60 3.7 0.1 3.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LOH1CR12 PF10158.9 ORY90871.1 - 8.1 6.5 12.8 6.2 6.9 0.2 4.6 4 0 0 4 4 3 0 Tumour suppressor protein Ribonuclease_P PF00825.18 ORY90873.1 - 3.5e-05 23.8 1.2 7.6e-05 22.8 1.2 1.5 1 0 0 1 1 1 1 Ribonuclease P Unstab_antitox PF09720.10 ORY90873.1 - 0.1 12.7 1.0 9.4 6.4 0.2 2.5 2 0 0 2 2 2 0 Putative addiction module component NmrA PF05368.13 ORY90874.1 - 5.3e-37 127.6 0.0 6.4e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY90874.1 - 1.6e-15 57.5 0.0 2.4e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 ORY90874.1 - 9.5e-06 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY90874.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.19 ORY90874.1 - 0.075 12.4 0.0 0.43 9.9 0.0 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 ORY90874.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ham1p_like PF01725.16 ORY90876.1 - 4e-56 189.9 0.0 4.4e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Clathrin_lg_ch PF01086.17 ORY90877.1 - 5.1e-54 183.8 2.1 6.5e-54 183.4 2.1 1.1 1 0 0 1 1 1 1 Clathrin light chain Tom22 PF04281.13 ORY90877.1 - 3.1 7.6 6.5 3.5 7.4 4.8 1.9 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ribosomal_S17_N PF16205.5 ORY90878.1 - 5.3e-31 106.8 0.5 9.3e-31 106.0 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORY90878.1 - 3.8e-28 97.4 0.8 6.9e-28 96.6 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 DUF922 PF06037.11 ORY90878.1 - 0.032 14.0 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) BPL_LplA_LipB PF03099.19 ORY90879.1 - 4.7e-09 36.2 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 ORY90879.1 - 0.018 15.0 0.0 0.11 12.5 0.0 2.4 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus PBP_like PF12727.7 ORY90879.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain Aim19 PF10315.9 ORY90880.1 - 5.6e-28 97.6 3.1 7.1e-28 97.2 3.1 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Tmemb_14 PF03647.13 ORY90880.1 - 0.035 14.8 0.8 0.052 14.3 0.8 1.4 1 1 0 1 1 1 0 Transmembrane proteins 14C Y_phosphatase2 PF03162.13 ORY90881.1 - 3.2e-59 199.2 0.0 3.4e-59 199.1 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY90881.1 - 1.4e-07 31.7 0.0 2.2e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY90881.1 - 0.00075 19.3 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY90881.1 - 0.0012 18.5 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Iso_dh PF00180.20 ORY90882.1 - 2.5e-116 388.6 0.0 2.9e-116 388.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PIN_6 PF17146.4 ORY90883.1 - 1.3e-28 99.3 0.1 3.2e-28 98.0 0.1 1.7 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 ORY90883.1 - 1.4e-25 89.2 0.2 2.3e-25 88.5 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 ORY90883.1 - 0.0031 17.1 4.2 0.026 14.2 0.5 2.5 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 ORY90883.1 - 0.011 15.7 1.0 0.019 15.0 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon WRNPLPNID PF15017.6 ORY90883.1 - 1.2 10.0 15.7 0.16 12.9 7.2 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box 4HBT PF03061.22 ORY90884.1 - 4.4e-09 36.6 0.0 9.4e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 ORY90884.1 - 0.0052 17.1 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily PRELI PF04707.14 ORY90885.1 - 3.9e-24 85.3 0.0 5.6e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family Med9 PF07544.13 ORY90886.1 - 5e-06 26.5 0.4 6.1e-06 26.2 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Uso1_p115_C PF04871.13 ORY90886.1 - 0.0041 17.5 0.3 0.0051 17.2 0.3 1.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 ORY90886.1 - 0.013 16.1 0.7 0.019 15.5 0.7 1.3 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Nop14 PF04147.12 ORY90887.1 - 1.2e-241 804.7 27.1 6.3e-185 617.0 5.6 3.1 1 1 2 3 3 3 2 Nop14-like family RXT2_N PF08595.11 ORY90887.1 - 0.002 18.2 1.6 0.002 18.2 1.6 5.0 4 1 0 4 4 4 1 RXT2-like, N-terminal Vac14_Fig4_bd PF11916.8 ORY90888.1 - 1.3e-79 266.0 9.0 2.1e-79 265.4 9.0 1.3 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 ORY90888.1 - 2e-36 124.4 0.0 5.1e-33 113.6 0.0 4.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 ORY90888.1 - 7.5e-10 38.2 0.6 0.0014 18.7 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 ORY90888.1 - 0.00067 19.7 0.3 0.46 10.5 0.2 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY90888.1 - 0.011 16.3 5.8 0.42 11.2 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat HEAT_2 PF13646.6 ORY90888.1 - 0.022 15.1 3.2 11 6.4 0.0 5.3 5 1 1 6 6 6 0 HEAT repeats Adaptin_N PF01602.20 ORY90888.1 - 0.11 11.1 3.4 1.8 7.0 1.8 3.2 3 1 1 4 4 4 0 Adaptin N terminal region CLASP_N PF12348.8 ORY90888.1 - 0.12 11.9 0.1 21 4.6 0.0 3.7 4 1 1 5 5 5 0 CLASP N terminal DUF3510 PF12022.8 ORY90888.1 - 0.6 10.5 3.5 0.67 10.4 0.4 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) PPP4R2 PF09184.11 ORY90888.1 - 9.5 5.7 8.3 17 4.9 8.3 1.3 1 0 0 1 1 1 0 PPP4R2 DUF498 PF04430.14 ORY90889.1 - 8.5e-32 109.5 0.0 1.2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF2371 PF10177.9 ORY90890.1 - 0.15 12.2 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) SNARE PF05739.19 ORY90890.1 - 0.64 10.1 3.6 0.25 11.4 0.7 1.8 2 0 0 2 2 2 0 SNARE domain Pex2_Pex12 PF04757.14 ORY90891.1 - 4.1e-33 114.9 2.7 5.5e-33 114.4 2.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 ORY90891.1 - 6.6e-11 41.9 4.9 9.8e-11 41.3 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY90891.1 - 1.9e-09 37.2 6.7 3.1e-09 36.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY90891.1 - 4.4e-09 36.5 9.1 7.5e-09 35.8 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY90891.1 - 2.7e-08 33.6 5.5 4.3e-08 32.9 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY90891.1 - 5.2e-07 29.6 1.9 5.2e-07 29.6 1.9 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY90891.1 - 8e-07 28.8 5.4 8e-07 28.8 5.4 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY90891.1 - 5.8e-06 26.5 5.3 1.1e-05 25.6 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY90891.1 - 1.1e-05 25.3 5.9 1.1e-05 25.3 5.9 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY90891.1 - 4.6e-05 23.5 6.0 8.6e-05 22.6 6.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 ORY90891.1 - 0.0097 16.0 4.5 0.018 15.1 4.5 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 ORY90891.1 - 0.015 15.3 1.4 0.026 14.6 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 ORY90891.1 - 0.59 10.1 4.1 1.1 9.2 4.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORY90891.1 - 2.5 7.9 6.9 4.9 7.0 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Gly_transf_sug PF04488.15 ORY90892.1 - 9.9e-12 45.3 0.0 1.7e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PRIMA1 PF16101.5 ORY90892.1 - 5.8 7.0 7.8 17 5.4 0.8 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 HAD_2 PF13419.6 ORY90893.1 - 2.6e-16 60.2 0.0 8.8e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY90893.1 - 6e-12 46.3 0.0 1.2e-11 45.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY90893.1 - 0.0006 19.8 0.0 0.0021 18.1 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 ORY90893.1 - 0.0099 16.3 0.0 0.024 15.0 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UTP15_C PF09384.10 ORY90894.1 - 1.2e-46 158.0 0.1 1.9e-46 157.4 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 ORY90894.1 - 1.1e-19 70.4 5.4 0.00044 21.0 0.1 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY90894.1 - 2.7e-05 24.4 0.1 3.7 7.9 0.0 4.8 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain RIX1 PF08167.12 ORY90895.1 - 2e-14 53.8 3.3 2e-14 53.8 3.3 1.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis RAP80_UIM PF18282.1 ORY90895.1 - 5.1 7.0 7.2 1.7 8.5 2.7 2.2 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif Methyltransf_25 PF13649.6 ORY90896.1 - 1.3e-07 32.2 0.0 2.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY90896.1 - 0.00016 22.3 0.0 0.00046 20.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY90896.1 - 0.0002 21.3 0.0 0.00029 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY90896.1 - 0.00076 20.1 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 ORY90896.1 - 0.0031 18.5 0.0 0.0057 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY90896.1 - 0.0075 16.1 0.0 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY90896.1 - 0.022 14.5 0.3 0.039 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 ORY90896.1 - 0.077 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Acetyltransf_1 PF00583.25 ORY90897.1 - 1.9e-14 53.9 0.1 2.3e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY90897.1 - 1.4e-07 31.8 0.0 2.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY90897.1 - 5.6e-07 29.5 0.0 7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY90897.1 - 0.0011 19.7 0.0 0.0012 19.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY90897.1 - 0.0054 16.7 0.0 0.009 16.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY90897.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 ORY90897.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BCAS2 PF05700.11 ORY90898.1 - 4.2e-62 209.5 0.7 4.7e-62 209.3 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ZapB PF06005.12 ORY90898.1 - 0.029 14.8 0.5 0.029 14.8 0.5 2.3 3 0 0 3 3 3 0 Cell division protein ZapB Csm1_N PF18504.1 ORY90898.1 - 0.045 14.1 1.7 3.2 8.2 0.5 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain APG6_N PF17675.1 ORY90898.1 - 0.046 14.2 3.1 0.15 12.6 1.8 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region SLY PF12485.8 ORY90898.1 - 0.14 12.8 0.3 0.22 12.2 0.3 1.3 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein ADIP PF11559.8 ORY90898.1 - 0.25 11.4 2.9 1.4 8.9 0.6 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 ORY90898.1 - 4.7 7.5 8.2 24 5.3 5.3 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain 4HBT_3 PF13622.6 ORY90899.1 - 8.8e-60 203.0 0.0 1e-59 202.8 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORY90899.1 - 1.9e-27 95.7 0.0 1.6e-19 70.1 0.0 3.0 2 1 1 3 3 3 2 Acyl-CoA thioesterase Phospholamban PF04272.14 ORY90899.1 - 0.22 11.0 0.1 0.43 10.1 0.1 1.4 1 0 0 1 1 1 0 Phospholamban Aminotran_1_2 PF00155.21 ORY90900.1 - 4.2e-56 190.7 0.0 4.9e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY90900.1 - 4.8e-07 29.4 0.0 8.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORY90900.1 - 0.00033 20.0 0.0 0.00051 19.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ORY90900.1 - 0.0025 16.4 0.0 0.0037 15.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 ORY90900.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III Aminotran_5 PF00266.19 ORY90900.1 - 0.045 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V GWT1 PF06423.12 ORY90902.1 - 1.7e-41 141.8 0.3 1.6e-40 138.7 0.0 2.5 2 1 0 2 2 2 1 GWT1 Complex1_30kDa PF00329.19 ORY90903.1 - 2.4e-48 163.8 0.0 3.2e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit GRIM-19 PF06212.12 ORY90905.1 - 3e-32 111.4 0.0 3.5e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein RRM_1 PF00076.22 ORY90906.1 - 8.2e-15 54.4 0.0 1.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 ORY90907.1 - 1.9e-61 206.4 0.1 2.2e-61 206.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY90907.1 - 4.1e-34 117.4 0.1 6.3e-34 116.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY90907.1 - 5.4e-12 45.5 0.0 7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY90907.1 - 7.7e-07 29.2 0.1 1.3e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY90907.1 - 0.00011 22.1 0.1 0.011 15.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 ORY90907.1 - 0.00017 21.9 0.0 0.0011 19.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 ORY90907.1 - 0.00047 19.7 0.1 0.0016 18.0 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY90907.1 - 0.0056 16.1 0.1 0.0082 15.5 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORY90907.1 - 0.014 14.8 0.0 0.034 13.6 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY90907.1 - 0.016 15.6 0.1 0.028 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 ORY90907.1 - 0.029 13.9 0.1 0.12 11.8 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 ORY90907.1 - 0.033 14.7 0.1 0.06 13.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 ORY90907.1 - 0.041 13.3 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein YvfG PF09628.10 ORY90907.1 - 0.048 14.0 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 YvfG protein AAA_24 PF13479.6 ORY90907.1 - 0.052 13.3 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain FAD-SLDH PF12318.8 ORY90907.1 - 0.06 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_7 PF12775.7 ORY90907.1 - 0.08 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MCM PF00493.23 ORY90907.1 - 0.095 11.8 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain AAA_21 PF13304.6 ORY90907.1 - 0.1 12.4 1.1 0.28 11.0 0.5 2.0 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY90907.1 - 0.3 10.8 1.4 0.57 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain XAP5 PF04921.14 ORY90908.1 - 4.6e-86 288.7 7.4 4.6e-86 288.7 7.4 1.9 1 1 1 2 2 2 1 XAP5, circadian clock regulator ApoLp-III PF07464.11 ORY90909.1 - 0.0017 18.5 6.6 0.0021 18.1 6.6 1.1 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DD_K PF12121.8 ORY90909.1 - 0.0082 16.2 2.1 0.0082 16.2 2.1 2.7 2 0 0 2 2 2 1 Dermaseptin HSP9_HSP12 PF04119.12 ORY90909.1 - 0.11 12.9 4.8 2 8.9 0.0 3.1 2 1 0 2 2 2 0 Heat shock protein 9/12 REF PF05755.12 ORY90909.1 - 0.62 9.8 7.0 0.28 11.0 2.1 1.9 1 1 1 2 2 2 0 Rubber elongation factor protein (REF) YtxH PF12732.7 ORY90909.1 - 2.2 8.9 13.4 44 4.7 13.3 2.2 1 1 0 1 1 1 0 YtxH-like protein CtnDOT_TraJ PF07863.11 ORY90909.1 - 6.7 7.4 6.3 11 6.7 1.8 2.2 1 1 1 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon 14-3-3 PF00244.20 ORY90910.1 - 1e-103 345.6 2.5 1.2e-103 345.4 2.5 1.0 1 0 0 1 1 1 1 14-3-3 protein SRTM1 PF15872.5 ORY90911.1 - 0.059 13.5 1.1 0.16 12.1 0.0 2.3 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Abhydrolase_1 PF00561.20 ORY90912.1 - 5.6e-07 29.5 0.0 7.9e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY90912.1 - 0.00034 21.3 0.3 0.00046 20.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY90912.1 - 0.00066 19.0 0.0 0.73 9.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 ORY90912.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family RINT1_TIP1 PF04437.13 ORY90913.1 - 1.1e-84 285.1 0.0 2e-84 284.3 0.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF1974 PF09317.11 ORY90913.1 - 0.0074 15.9 0.5 0.017 14.7 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1974) DUF4407 PF14362.6 ORY90913.1 - 0.048 13.0 3.1 0.074 12.4 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_GPO PF05929.11 ORY90913.1 - 0.21 11.2 3.9 0.35 10.4 3.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase F-box-like PF12937.7 ORY90915.1 - 0.00021 21.1 0.5 0.00063 19.6 0.5 1.9 1 0 0 1 1 1 1 F-box-like NifU_N PF01592.16 ORY90915.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 NifU-like N terminal domain DUF3246 PF11596.8 ORY90915.1 - 0.23 10.9 0.3 0.32 10.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RasGAP PF00616.19 ORY90917.1 - 5.7e-26 91.5 0.0 5.6e-17 62.1 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 ORY90917.1 - 6.9e-10 39.2 0.1 1.6e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HEAT PF02985.22 ORY90917.1 - 0.17 12.2 4.0 39 4.9 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat TMEM135_C_rich PF15982.5 ORY90918.1 - 1.1e-08 35.8 0.7 2.5e-07 31.4 0.7 2.7 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 ORY90918.1 - 8.7e-05 22.9 1.0 0.0047 17.3 0.4 2.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family cobW PF02492.19 ORY90919.1 - 2e-49 167.5 0.2 2.7e-49 167.2 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 ORY90919.1 - 2.7e-05 23.8 0.0 7.2e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY90919.1 - 9e-05 22.4 0.2 0.49 10.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY90919.1 - 0.00023 20.8 0.0 0.57 9.7 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY90919.1 - 0.00072 19.6 0.0 0.0015 18.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY90919.1 - 0.00074 20.1 0.0 0.0016 19.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain CobW_C PF07683.14 ORY90919.1 - 0.0019 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 ORY90919.1 - 0.013 15.9 0.1 0.028 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 ORY90919.1 - 0.022 13.7 0.1 0.28 10.2 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ORY90919.1 - 0.046 13.6 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 ORY90919.1 - 0.094 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 ORY90919.1 - 0.095 11.7 0.1 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 ORY90919.1 - 0.098 13.2 0.0 0.27 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 ORY90919.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DSPc PF00782.20 ORY90920.1 - 1.9e-28 98.9 0.0 2.8e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF3685 PF12452.8 ORY90920.1 - 0.0096 15.6 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3685) Y_phosphatase PF00102.27 ORY90920.1 - 0.013 15.0 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 ORY90920.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain Arm PF00514.23 ORY90921.1 - 3.2e-17 61.9 18.9 0.00018 21.4 0.0 8.7 9 0 0 9 9 9 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY90921.1 - 8.4e-08 32.5 19.9 0.0016 18.8 0.4 6.7 5 1 2 7 7 7 3 HEAT repeats Cnd1 PF12717.7 ORY90921.1 - 1.9e-06 28.0 6.5 0.013 15.5 0.2 5.0 4 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY90921.1 - 2.3e-06 27.4 15.1 0.0058 16.8 0.2 7.2 8 0 0 8 8 8 2 HEAT repeat Adaptin_N PF01602.20 ORY90921.1 - 2.6e-05 23.0 4.0 6.4e-05 21.7 0.7 2.8 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 ORY90921.1 - 4.7e-05 23.5 0.1 0.024 14.8 0.0 4.0 3 1 1 4 4 4 1 V-ATPase subunit H Arm_2 PF04826.13 ORY90921.1 - 0.00013 21.6 0.6 0.13 11.7 0.0 3.3 2 1 1 3 3 3 2 Armadillo-like HEAT_EZ PF13513.6 ORY90921.1 - 0.014 15.9 21.0 3 8.5 0.2 7.6 8 0 0 8 8 8 0 HEAT-like repeat CLASP_N PF12348.8 ORY90921.1 - 0.045 13.3 5.8 4.4 6.8 0.0 4.6 3 1 2 5 5 5 0 CLASP N terminal DUF3361 PF11841.8 ORY90921.1 - 0.11 12.5 0.1 0.6 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 ORY90921.1 - 0.17 12.1 2.8 18 5.6 0.0 4.6 4 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 WAPL PF07814.13 ORY90921.1 - 0.21 10.3 10.4 0.13 11.1 0.2 4.1 3 1 1 4 4 4 0 Wings apart-like protein regulation of heterochromatin NOG1_N PF17835.1 ORY90922.1 - 7.3e-48 162.6 0.6 1.6e-46 158.2 0.2 2.5 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 ORY90922.1 - 2e-27 94.7 0.1 5.2e-27 93.4 0.1 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 ORY90922.1 - 1.8e-17 63.4 0.0 5.8e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.11 ORY90922.1 - 1.2e-13 50.8 11.8 1.8e-13 50.2 9.1 2.7 2 1 0 2 2 2 1 NOGCT (NUC087) domain FeoB_N PF02421.18 ORY90922.1 - 3.5e-09 36.4 0.0 7.8e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY90922.1 - 0.0021 18.2 0.0 3.6 7.6 0.0 2.8 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORY90922.1 - 0.011 15.7 0.1 1.8 8.4 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase Spt5_N PF11942.8 ORY90922.1 - 0.026 15.5 1.1 0.026 15.5 1.1 3.4 2 1 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal Roc PF08477.13 ORY90922.1 - 0.026 14.7 0.0 0.16 12.2 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY90922.1 - 0.035 14.5 0.0 0.64 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Sushi_2 PF09014.10 ORY90922.1 - 0.06 13.2 0.5 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Spc7 PF08317.11 ORY90922.1 - 0.085 11.7 0.7 0.16 10.8 0.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein AIG1 PF04548.16 ORY90922.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF4050 PF13259.6 ORY90923.1 - 0.015 15.6 0.4 0.13 12.6 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) LSM PF01423.22 ORY90924.1 - 4.5e-19 67.9 0.4 5.8e-19 67.5 0.4 1.2 1 0 0 1 1 1 1 LSM domain Cas_Cas2CT1978 PF09707.10 ORY90924.1 - 0.0076 16.3 0.1 0.013 15.6 0.1 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas2CT1978) zf-U1 PF06220.12 ORY90925.1 - 2.1e-19 69.0 5.3 2.8e-19 68.6 5.3 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 ORY90925.1 - 8.4 6.8 8.0 65 4.0 8.0 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DEAD PF00270.29 ORY90927.1 - 3e-42 144.3 0.0 4.8e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY90927.1 - 4e-23 81.9 0.0 1.2e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY90927.1 - 5.4e-05 23.3 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY90927.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 ORY90927.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase FAA_hydrolase PF01557.18 ORY90928.1 - 6.1e-50 169.9 0.0 7.7e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family F-box-like PF12937.7 ORY90930.1 - 0.0016 18.2 2.1 0.0059 16.5 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 ORY90930.1 - 0.039 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 F-box F-box-like_2 PF13013.6 ORY90930.1 - 0.047 13.7 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 F-box-like domain DUF202 PF02656.15 ORY90931.1 - 6.3e-15 55.4 2.4 6.3e-15 55.4 2.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF3149 PF11346.8 ORY90931.1 - 0.088 12.4 0.9 0.088 12.4 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) RRM_1 PF00076.22 ORY90932.1 - 1.4e-10 40.9 0.0 1.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTH2 PF01981.16 ORY90933.1 - 3.1e-47 159.7 0.8 3.7e-47 159.4 0.8 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2573 PF10835.8 ORY90933.1 - 0.096 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) Hydantoinase_B PF02538.14 ORY90934.1 - 5e-219 728.0 0.0 5.8e-219 727.8 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Clathrin PF00637.20 ORY90935.1 - 3.3e-28 98.4 0.8 1.3e-27 96.4 0.4 2.3 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 ORY90935.1 - 0.00026 21.2 0.3 0.16 12.3 0.1 2.7 1 1 1 2 2 2 2 Vacuolar sorting protein 39 domain 1 NodA PF02474.15 ORY90935.1 - 0.11 12.2 0.0 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Nodulation protein A (NodA) Pox_Ag35 PF03286.14 ORY90935.1 - 2 8.2 6.8 9.1 6.0 0.7 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 ORY90935.1 - 3.6 7.1 14.1 5.9 6.4 14.1 1.2 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 ORY90935.1 - 4.6 6.6 14.4 8.1 5.8 14.4 1.3 1 0 0 1 1 1 0 SDA1 Tub_N PF16322.5 ORY90935.1 - 5.5 7.3 13.1 11 6.4 13.1 1.4 1 0 0 1 1 1 0 Tubby N-terminal Ras PF00071.22 ORY90936.1 - 1e-46 158.5 0.0 1.1e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY90936.1 - 5.3e-23 81.5 0.0 6.7e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY90936.1 - 2.1e-07 30.6 0.0 3.2e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY90936.1 - 0.0034 16.9 0.0 0.01 15.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain BTG PF07742.12 ORY90937.1 - 1.4e-23 82.9 0.0 2.3e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 BTG family XG_FTase PF03254.13 ORY90938.1 - 9.5e-07 27.8 0.0 0.00051 18.8 0.0 2.5 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase NodZ PF05830.11 ORY90938.1 - 0.12 11.2 0.0 13 4.5 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein Z (NodZ) XG_FTase PF03254.13 ORY90939.1 - 9e-09 34.5 0.0 2.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase NodZ PF05830.11 ORY90939.1 - 0.0053 15.6 0.0 0.66 8.7 0.0 2.0 2 0 0 2 2 2 2 Nodulation protein Z (NodZ) BTB PF00651.31 ORY90940.1 - 6e-12 45.8 0.0 8.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 ORY90940.1 - 0.00033 20.8 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain CTP_transf_like PF01467.26 ORY90941.1 - 1e-05 25.8 0.0 8.9e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase-like HIGH_NTase1_ass PF16581.5 ORY90941.1 - 0.031 14.3 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Citrate_ly_lig PF08218.11 ORY90941.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain AbiEi_4 PF13338.6 ORY90941.1 - 0.28 11.4 1.4 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin F-box-like PF12937.7 ORY90942.1 - 0.00055 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY90942.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box AAA_27 PF13514.6 ORY90942.1 - 0.077 12.6 0.1 0.29 10.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain LRR_9 PF14580.6 ORY90943.1 - 3.7e-49 166.6 0.0 5.1e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORY90943.1 - 2.6e-08 34.0 5.8 0.013 15.9 0.7 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY90943.1 - 3.3e-07 30.0 4.6 2.4e-06 27.2 4.3 2.6 3 1 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 ORY90943.1 - 0.022 15.3 7.2 60 4.8 0.5 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY90943.1 - 0.07 13.2 6.6 42 4.6 0.6 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Septin PF00735.18 ORY90944.1 - 9.1e-121 402.4 0.1 9.1e-121 402.4 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY90944.1 - 2e-08 34.3 0.9 4.2e-08 33.3 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY90944.1 - 1.7e-05 24.8 3.6 7.5e-05 22.7 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 ORY90944.1 - 0.00024 20.7 7.2 0.00037 20.1 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 ORY90944.1 - 0.00048 20.6 6.5 0.0061 17.1 0.2 2.8 1 1 1 2 2 2 1 ABC transporter Ras PF00071.22 ORY90944.1 - 0.00062 19.4 0.2 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 ORY90944.1 - 0.0013 19.0 0.3 0.0053 17.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY90944.1 - 0.0049 17.3 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 ORY90944.1 - 0.01 15.2 2.0 0.017 14.5 0.0 2.4 2 0 0 2 2 2 0 AIG1 family AAA_29 PF13555.6 ORY90944.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 ORY90944.1 - 0.037 14.2 0.0 0.097 12.9 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Coiled-coil_56 PF09813.9 ORY90944.1 - 0.044 13.8 2.6 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 Dynamin_N PF00350.23 ORY90944.1 - 0.05 13.7 5.3 1.2 9.1 0.2 3.2 2 1 1 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.15 ORY90944.1 - 0.12 12.0 5.5 0.19 11.3 5.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit RNA_helicase PF00910.22 ORY90944.1 - 0.18 12.2 0.2 1 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase DUF3987 PF13148.6 ORY90944.1 - 8.1 5.3 9.8 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) RPN13_C PF16550.5 ORY90947.1 - 3.5e-22 78.7 0.0 5.4e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 ORY90947.1 - 2.2e-21 76.2 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF3235 PF11574.8 ORY90947.1 - 2.9 8.8 7.6 0.74 10.7 4.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) DUF4486 PF14858.6 ORY90948.1 - 0.1 11.1 0.2 0.13 10.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) DUF2975 PF11188.8 ORY90951.1 - 0.073 13.0 0.2 0.1 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Exo84_C PF16528.5 ORY90951.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Exocyst component 84 C-terminal DPBB_1 PF03330.18 ORY90952.1 - 4.6e-09 36.4 0.1 1.6e-08 34.7 0.1 2.0 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 ORY90952.1 - 0.00068 19.5 0.3 0.00068 19.5 0.3 2.2 2 1 1 3 3 3 1 Barwin family Utp14 PF04615.13 ORY90952.1 - 1.5 7.3 14.2 1.7 7.1 14.2 1.1 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 ORY90952.1 - 6.2 5.4 17.3 8.3 5.0 17.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DPBB_1 PF03330.18 ORY90953.1 - 5.7e-08 32.9 1.8 2.5e-07 30.9 0.1 2.5 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 ORY90953.1 - 0.0015 18.4 0.6 0.0053 16.6 0.6 1.9 1 0 0 1 1 1 1 Barwin family EPSP_synthase PF00275.20 ORY91446.1 - 5.1e-115 384.5 0.0 7.7e-115 383.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ORY91446.1 - 2.1e-97 325.4 0.9 7.1e-97 323.7 0.2 2.1 3 0 0 3 3 3 1 3-dehydroquinate synthase DHquinase_I PF01487.15 ORY91446.1 - 4.8e-48 164.4 0.0 9.2e-48 163.5 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 ORY91446.1 - 1.2e-30 106.7 0.0 1.9e-29 102.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 ORY91446.1 - 3.7e-25 88.0 0.0 1.4e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ORY91446.1 - 1.8e-08 34.0 0.0 5e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 ORY91446.1 - 5.2e-08 32.9 0.1 1.1e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 ORY91446.1 - 4.3e-07 30.1 0.0 9.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY91446.1 - 0.041 14.1 0.0 0.52 10.6 0.0 2.7 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Exonuc_VII_L PF02601.15 ORY91446.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR_HSR1 PF01926.23 ORY91447.1 - 3e-16 59.5 0.0 4e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY91447.1 - 6.6e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY91447.1 - 0.00027 21.1 0.4 0.001 19.2 0.1 2.1 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 ORY91447.1 - 0.00076 19.4 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 ORY91447.1 - 0.0048 16.2 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Trypan_PARP PF05887.11 ORY91447.1 - 0.088 12.8 27.4 0.051 13.6 16.1 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Roc PF08477.13 ORY91447.1 - 0.091 13.0 0.0 0.35 11.1 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_pol_Rpc4 PF05132.14 ORY91447.1 - 2.4 8.6 8.6 0.82 10.1 1.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 Zn_clus PF00172.18 ORY91448.1 - 0.00028 20.9 9.1 0.00042 20.4 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIP5K PF01504.18 ORY91449.1 - 1.4e-41 142.6 0.1 1.5e-33 116.3 0.2 2.5 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 ORY91449.1 - 4.8e-33 114.5 0.0 7.1e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 ORY91449.1 - 2.5e-17 62.7 10.1 2.5e-17 62.7 10.1 1.9 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.21 ORY91449.1 - 0.23 11.7 10.1 0.44 10.8 5.1 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 ORY91449.1 - 1.9 8.7 5.0 8.1 6.7 5.0 2.1 1 0 0 1 1 1 0 FYVE-type zinc finger CDC45 PF02724.14 ORY91449.1 - 2.3 6.4 8.1 4.1 5.6 8.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Lactonase PF10282.9 ORY91450.1 - 2.3e-61 208.0 0.0 2.9e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Imm32 PF15566.6 ORY91450.1 - 0.11 12.3 0.5 5 7.0 0.0 3.0 3 0 0 3 3 3 0 Immunity protein 32 Lactonase PF10282.9 ORY91451.1 - 4e-65 220.3 0.0 5e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Lipid_DES PF08557.10 ORY91452.1 - 0.28 10.7 0.9 0.54 9.8 0.9 1.5 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Gemin7 PF11095.8 ORY91453.1 - 0.13 12.1 1.6 15 5.6 0.2 2.3 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) PP-binding PF00550.25 ORY91454.1 - 9e-14 51.6 0.6 1.2e-13 51.2 0.6 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORY91454.1 - 0.00017 21.7 0.2 0.00025 21.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier GARS_A PF01071.19 ORY91455.1 - 2.1e-83 278.9 0.1 4e-83 278.0 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 ORY91455.1 - 3.3e-38 131.3 0.0 1.3e-37 129.4 0.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 ORY91455.1 - 3.9e-33 114.1 0.0 2.1e-32 111.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ORY91455.1 - 5.2e-31 106.8 0.5 1.2e-30 105.6 0.5 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 ORY91455.1 - 1.3e-14 54.6 1.6 5.1e-14 52.7 1.6 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain CPSase_L_D2 PF02786.17 ORY91455.1 - 0.0013 18.3 0.2 0.0031 17.0 0.2 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 ORY91455.1 - 0.005 16.4 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 ORY91455.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 ORY91455.1 - 0.033 13.8 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Malic_M PF03949.15 ORY91456.1 - 0.0022 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain TEX19 PF15553.6 ORY91456.1 - 0.076 13.0 1.2 0.2 11.6 1.2 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 CGI-121 PF08617.10 ORY91458.1 - 4.7e-42 143.9 0.0 5.4e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Response_reg PF00072.24 ORY91460.1 - 1.3e-20 73.6 0.0 6.1e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain S4 PF01479.25 ORY91461.1 - 8.9e-12 44.5 0.4 2.3e-11 43.2 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY91461.1 - 2.4e-10 41.2 0.8 2.4e-10 41.2 0.8 1.7 2 1 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain EXOSC1 PF10447.9 ORY91462.1 - 1.9e-15 57.4 0.3 8.1e-11 42.5 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 ORY91462.1 - 8.3e-08 31.9 1.1 8.3e-08 31.9 1.1 2.3 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region SNF2_N PF00176.23 ORY91463.1 - 1.2e-54 185.3 0.0 2.7e-45 154.6 0.0 2.6 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY91463.1 - 1.8e-18 66.9 0.0 2.5e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY91463.1 - 7.1e-10 39.2 0.1 1.9e-09 37.7 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 ORY91463.1 - 4.7e-08 32.8 8.7 4.7e-08 32.8 8.7 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY91463.1 - 3e-07 30.2 8.6 3e-07 30.2 8.6 2.8 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 ORY91463.1 - 8.5e-07 28.9 0.0 2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 ORY91463.1 - 1.3e-06 28.1 7.6 1.3e-06 28.1 7.6 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY91463.1 - 2e-06 28.0 8.5 2e-06 28.0 8.5 2.6 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 ORY91463.1 - 3.7e-05 23.8 9.3 3.7e-05 23.8 9.3 2.3 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY91463.1 - 9.4e-05 22.3 8.2 9.4e-05 22.3 8.2 2.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY91463.1 - 0.00014 21.8 8.1 0.00014 21.8 8.1 2.5 2 1 0 2 2 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 ORY91463.1 - 0.00041 20.4 0.9 0.0016 18.5 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein AAA_34 PF13872.6 ORY91463.1 - 0.00056 18.9 0.0 0.0012 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.8 ORY91463.1 - 0.00095 18.9 4.9 0.0019 17.9 4.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 ORY91463.1 - 0.0016 18.6 3.7 0.0016 18.6 3.7 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY91463.1 - 0.0023 17.7 1.9 0.0061 16.4 1.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 ORY91463.1 - 0.0039 17.3 4.4 0.0039 17.3 4.4 2.1 2 0 0 2 2 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ORY91463.1 - 0.0042 16.9 6.8 0.0042 16.9 6.8 2.0 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 DEAD_2 PF06733.15 ORY91463.1 - 0.0091 15.6 0.8 0.071 12.7 0.0 2.5 2 0 0 2 2 2 1 DEAD_2 AAA_22 PF13401.6 ORY91463.1 - 0.024 14.9 0.1 11 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 ORY91463.1 - 0.13 12.2 0.0 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain RdRP_3 PF00998.23 ORY91463.1 - 0.93 8.1 4.4 1.5 7.5 4.4 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase RRM_1 PF00076.22 ORY91464.1 - 1.1e-24 86.0 0.1 1.4e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY91464.1 - 1e-12 47.7 0.0 2.3e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY91464.1 - 0.0027 17.5 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif DUF1027 PF06265.11 ORY91464.1 - 0.03 14.3 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1027) PHM7_cyt PF14703.6 ORY91464.1 - 0.38 11.0 2.7 19 5.4 0.1 3.6 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter ApbA_C PF08546.11 ORY91465.1 - 1.2e-24 86.9 0.0 3.3e-24 85.5 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 ORY91465.1 - 1.1e-22 80.3 0.0 4.9e-16 58.7 0.0 2.4 1 1 0 2 2 2 2 Ketopantoate reductase PanE/ApbA DUF2058 PF09831.9 ORY91465.1 - 1.4 9.0 8.5 2 8.5 8.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) GDI PF00996.18 ORY91466.1 - 7.1e-220 730.0 0.1 8.1e-220 729.8 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pkinase PF00069.25 ORY91469.1 - 2.3e-73 246.8 0.0 3.1e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY91469.1 - 7.7e-37 127.0 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORY91469.1 - 2.7e-15 56.4 0.0 5.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 ORY91469.1 - 3.4e-06 26.6 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 ORY91469.1 - 5.8e-05 23.3 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 ORY91469.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 ORY91469.1 - 0.0026 17.9 0.0 0.006 16.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family FHA_2 PF17913.1 ORY91469.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain APH PF01636.23 ORY91469.1 - 0.0091 15.9 0.0 3 7.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family URO-D PF01208.17 ORY91470.1 - 1.2e-108 363.3 0.0 1.5e-108 363.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Proteasome PF00227.26 ORY91471.1 - 3.7e-50 170.1 0.0 4.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY91471.1 - 1.7e-14 53.2 0.1 3e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF4828 PF16110.5 ORY91471.1 - 0.13 12.8 0.0 0.89 10.1 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4828) Fra10Ac1 PF09725.9 ORY91472.1 - 1.1e-43 148.2 0.1 1.7e-43 147.6 0.1 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 NDUF_B4 PF07225.12 ORY91473.1 - 0.00022 21.1 0.1 0.00033 20.5 0.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PAS_9 PF13426.7 ORY91474.1 - 1.7e-20 73.2 0.0 2.2e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY91474.1 - 7.6e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ORY91474.1 - 2.4e-05 24.6 0.0 0.00073 19.8 0.0 2.7 2 1 0 2 2 2 1 PAS fold PAS_3 PF08447.12 ORY91474.1 - 0.00084 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORY91474.1 - 0.11 12.5 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 PAS domain MFS_1 PF07690.16 ORY91475.1 - 1.5e-37 129.3 25.7 1.5e-37 129.3 25.7 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY91475.1 - 2.3e-12 46.6 21.8 8.5e-12 44.7 21.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.6 ORY91475.1 - 0.14 12.1 2.5 0.41 10.7 2.5 1.8 1 0 0 1 1 1 0 Glycine zipper DUF4179 PF13786.6 ORY91475.1 - 3.6 8.1 4.2 28 5.3 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Gemin7 PF11095.8 ORY91476.1 - 0.16 11.9 1.5 16 5.4 0.1 2.3 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Arrestin_N PF00339.29 ORY91477.1 - 1.8e-06 28.1 0.1 6.7e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY91477.1 - 0.0028 18.1 0.0 0.03 14.8 0.0 2.2 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Cpn60_TCP1 PF00118.24 ORY91478.1 - 2.9e-154 514.3 5.2 3.6e-154 514.0 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TPR_1 PF00515.28 ORY91479.1 - 9.5e-33 110.7 0.2 0.00092 18.9 0.1 11.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY91479.1 - 8.9e-29 97.3 12.3 0.088 13.0 0.1 13.0 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORY91479.1 - 1.3e-18 66.1 39.2 0.014 16.1 0.1 13.0 12 4 4 16 16 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY91479.1 - 1.5e-18 67.0 21.9 0.026 15.0 0.1 10.8 9 3 2 11 11 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY91479.1 - 1.4e-17 64.1 31.1 0.0037 17.9 0.2 11.3 10 2 3 13 13 13 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY91479.1 - 2.5e-15 55.3 3.4 1.3 9.4 0.0 10.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 ORY91479.1 - 4.2e-13 49.0 19.1 0.049 14.3 0.0 12.9 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY91479.1 - 4.2e-12 45.2 16.9 0.42 10.7 0.0 10.3 10 2 0 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY91479.1 - 7.7e-10 38.9 28.5 0.06 13.6 0.0 10.8 8 3 3 12 12 12 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY91479.1 - 5.3e-05 23.3 7.4 2.6 8.3 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY91479.1 - 8.1e-05 22.4 16.1 0.044 13.7 0.0 8.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY91479.1 - 0.00018 21.1 6.3 13 5.5 0.0 7.9 9 0 0 9 9 9 0 TPR repeat TPR_17 PF13431.6 ORY91479.1 - 0.0021 18.3 4.7 73 4.1 0.0 7.8 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY91479.1 - 0.0099 15.1 0.2 0.0099 15.1 0.2 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY91479.1 - 0.01 16.1 11.0 0.33 11.2 0.3 5.9 7 0 0 7 7 7 1 Anaphase-promoting complex, cyclosome, subunit 3 ADIP PF11559.8 ORY91480.1 - 0.00022 21.3 10.2 0.00037 20.6 0.4 2.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 ORY91480.1 - 0.00042 19.3 2.0 0.00042 19.3 2.0 2.1 2 0 0 2 2 2 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 ORY91480.1 - 0.00055 19.9 0.8 0.00055 19.9 0.8 3.4 2 2 1 3 3 3 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 ORY91480.1 - 0.00078 19.7 19.4 0.0018 18.5 5.0 2.6 1 1 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 ORY91480.1 - 0.0053 17.0 10.3 0.17 12.2 4.9 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 ORY91480.1 - 0.0063 16.0 13.8 0.12 11.8 3.6 2.1 2 0 0 2 2 2 2 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 ORY91480.1 - 0.0098 16.1 8.7 0.0098 16.1 8.7 2.2 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding ERM PF00769.19 ORY91480.1 - 0.011 15.5 21.0 0.13 12.1 3.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family T3SSipB PF16535.5 ORY91480.1 - 0.022 15.2 0.4 0.022 15.2 0.4 1.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB Tektin PF03148.14 ORY91480.1 - 0.05 12.3 10.9 0.25 10.0 1.5 2.1 2 0 0 2 2 2 0 Tektin family Cnn_1N PF07989.11 ORY91480.1 - 0.093 12.9 8.3 0.15 12.3 1.5 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 ORY91480.1 - 0.16 12.0 17.2 0.31 11.1 4.3 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 ORY91480.1 - 0.3 11.8 9.3 1.1 9.9 0.4 2.7 1 1 2 3 3 3 0 Initiation control protein YabA KxDL PF10241.9 ORY91480.1 - 0.35 11.2 4.3 1.4 9.3 0.1 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein HIP1_clath_bdg PF16515.5 ORY91480.1 - 0.45 11.2 18.0 0.088 13.4 2.9 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SLATT_5 PF18160.1 ORY91480.1 - 0.49 9.7 1.8 1.1 8.6 0.5 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Fez1 PF06818.15 ORY91480.1 - 0.6 10.5 15.7 3.9 7.9 13.8 2.1 1 1 1 2 2 2 0 Fez1 DUF4201 PF13870.6 ORY91480.1 - 0.84 9.4 11.0 1.4 8.6 2.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Atg14 PF10186.9 ORY91480.1 - 1.1 8.3 10.5 1.6 7.7 1.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ORY91480.1 - 1.1 8.5 7.4 4 6.7 7.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cluap1 PF10234.9 ORY91480.1 - 1.3 8.3 9.7 0.2 11.0 1.5 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 GAS PF13851.6 ORY91480.1 - 1.7 8.0 12.2 0.87 8.9 2.2 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CP12 PF02672.15 ORY91480.1 - 2 9.2 7.3 0.12 13.2 0.9 2.2 2 1 0 2 2 1 0 CP12 domain FPP PF05911.11 ORY91480.1 - 2.1 6.4 17.6 0.12 10.6 1.9 2.2 2 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil Filament PF00038.21 ORY91480.1 - 2.2 7.8 18.4 8.8 5.8 18.4 1.8 1 1 0 1 1 1 0 Intermediate filament protein FlaC_arch PF05377.11 ORY91480.1 - 2.3 8.7 6.5 13 6.2 0.5 3.6 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF2796 PF10986.8 ORY91480.1 - 2.5 8.0 28.1 0.46 10.4 22.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2796) KASH_CCD PF14662.6 ORY91480.1 - 3.7 7.3 15.0 7.1 6.4 4.3 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 ORY91480.1 - 4 7.6 5.1 41 4.4 0.1 3.0 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 ORY91480.1 - 4.2 5.4 12.0 0.38 8.9 0.8 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA YscO PF07321.12 ORY91480.1 - 5.6 6.9 18.7 4.4 7.3 6.2 3.2 2 2 1 3 3 3 0 Type III secretion protein YscO Neur_chan_memb PF02932.16 ORY91480.1 - 5.8 6.9 6.4 7.5 6.5 3.4 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF724 PF05266.14 ORY91480.1 - 7.4 6.3 12.9 1.5 8.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) SelP_N PF04592.14 ORY91480.1 - 7.7 5.8 24.8 0.59 9.5 19.9 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Zip PF02535.22 ORY91480.1 - 7.9 5.6 13.5 0.29 10.3 8.0 1.4 2 0 0 2 2 1 0 ZIP Zinc transporter BBP1_C PF15272.6 ORY91480.1 - 9.8 6.0 12.6 8 6.2 0.4 2.4 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Filament PF00038.21 ORY91482.1 - 2.2e-06 27.5 219.2 0.0026 17.4 21.7 11.8 1 1 8 10 10 10 6 Intermediate filament protein Spc7 PF08317.11 ORY91482.1 - 5.1e-05 22.3 250.5 0.00078 18.4 5.5 14.7 2 1 14 18 18 18 11 Spc7 kinetochore protein ATG16 PF08614.11 ORY91482.1 - 0.00038 20.8 309.2 0.013 15.7 5.6 15.2 1 1 15 17 17 16 5 Autophagy protein 16 (ATG16) HOOK PF05622.12 ORY91482.1 - 0.00055 18.2 44.7 0.00055 18.2 44.7 8.5 1 1 5 8 8 8 2 HOOK protein TPR_MLP1_2 PF07926.12 ORY91482.1 - 0.0014 18.7 22.7 0.0014 18.7 22.7 17.6 4 3 11 17 17 17 11 TPR/MLP1/MLP2-like protein ADIP PF11559.8 ORY91482.1 - 0.0038 17.3 0.4 0.0038 17.3 0.4 19.4 4 1 14 19 19 19 7 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 ORY91482.1 - 0.0062 16.5 1.3 0.0062 16.5 1.3 24.5 12 6 12 27 27 26 10 TATA element modulatory factor 1 DNA binding Golgin_A5 PF09787.9 ORY91482.1 - 0.13 11.7 229.4 0.071 12.6 14.4 13.5 2 1 11 14 14 14 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 ORY91482.1 - 3.7 7.7 133.6 0.14 12.4 1.3 16.2 5 2 13 19 19 19 0 Fibrinogen alpha/beta chain family CbiG_N PF11760.8 ORY91482.1 - 6.3 6.9 9.6 1.6 8.8 0.0 4.0 5 0 0 5 5 4 0 Cobalamin synthesis G N-terminal DUF3226 PF11536.8 ORY91482.1 - 7 6.2 15.5 6.8 6.3 0.6 5.3 5 0 0 5 5 5 0 Protein of unknown function (DUF3226) PfkB PF00294.24 ORY91483.1 - 3.7e-70 236.6 0.7 4.2e-70 236.5 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORY91483.1 - 0.00083 18.8 0.0 0.0022 17.4 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Swi5 PF07061.11 ORY91484.1 - 3.1e-23 81.7 2.1 3.5e-23 81.5 2.1 1.0 1 0 0 1 1 1 1 Swi5 DUF1192 PF06698.11 ORY91484.1 - 0.028 14.5 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) FAM76 PF16046.5 ORY91484.1 - 0.048 13.0 0.8 0.052 12.9 0.8 1.0 1 0 0 1 1 1 0 FAM76 protein DUF4446 PF14584.6 ORY91484.1 - 0.099 12.6 0.5 0.11 12.4 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Lzipper-MIP1 PF14389.6 ORY91484.1 - 0.12 12.6 1.9 0.29 11.4 1.9 1.8 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 MARVEL PF01284.23 ORY91486.1 - 3.1e-13 50.0 20.6 4.2e-13 49.5 20.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Frag1 PF10277.9 ORY91486.1 - 0.047 13.2 13.7 0.029 13.9 9.2 1.9 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family ABC2_membrane PF01061.24 ORY91486.1 - 0.45 9.9 15.7 0.063 12.7 9.9 2.0 2 0 0 2 2 2 0 ABC-2 type transporter DUF5090 PF17009.5 ORY91486.1 - 0.89 9.5 4.3 1.5 8.8 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) FAA_hydrolase PF01557.18 ORY91487.1 - 2e-51 174.7 0.0 2.4e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 ORY91487.1 - 0.027 14.3 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 KH domain Med13_C PF06333.12 ORY91488.1 - 7.1e-25 88.0 2.4 7.1e-25 88.0 2.4 3.6 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain MID_MedPIWI PF18296.1 ORY91488.1 - 0.0005 19.9 5.0 0.0071 16.2 0.0 3.7 4 1 1 5 5 5 2 MID domain of medPIWI ComFB PF10719.9 ORY91489.1 - 0.039 14.0 0.2 0.039 14.0 0.2 1.7 2 0 0 2 2 2 0 Late competence development protein ComFB Pantoate_transf PF02548.15 ORY91490.1 - 7.5e-96 320.5 0.0 1.2e-95 319.8 0.0 1.3 1 1 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 ORY91490.1 - 2.4e-05 23.9 0.0 6.5e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Methyltransf_28 PF02636.17 ORY91491.1 - 1.9e-67 227.7 0.0 8.5e-67 225.5 0.0 1.8 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase VWA_2 PF13519.6 ORY91492.1 - 5.1e-23 81.8 0.0 2.9e-22 79.3 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 ORY91492.1 - 6.6e-12 44.5 17.6 5.2e-05 22.9 3.6 3.8 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.14 ORY91492.1 - 4.2e-07 30.0 0.0 6.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like RRM_Rrp7 PF17799.1 ORY91492.1 - 0.16 11.8 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain O-FucT PF10250.9 ORY91493.1 - 5.8e-10 39.4 0.0 8.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 ORY91493.1 - 0.002 17.4 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 11 Cys_box PF17869.1 ORY91493.1 - 0.024 14.8 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Anosmin cysteine rich domain CN_hydrolase PF00795.22 ORY91494.1 - 4.3e-53 180.3 0.0 5.7e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asp PF00026.23 ORY91495.1 - 3.8e-62 210.5 10.7 7.8e-62 209.5 10.7 1.5 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 ORY91495.1 - 1.3e-05 25.8 5.6 0.00035 21.2 0.2 3.9 3 1 0 3 3 3 1 Aspartyl protease TAXi_N PF14543.6 ORY91495.1 - 0.00072 19.8 7.3 0.00072 19.8 7.3 3.7 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ORY91495.1 - 0.0027 18.2 1.3 0.033 14.7 0.1 3.1 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 ORY91495.1 - 0.034 13.9 0.1 8.3 6.2 0.1 2.4 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal PB1 PF00564.24 ORY91497.1 - 3e-08 33.5 0.0 8.2e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 PB1 domain Macoilin PF09726.9 ORY91497.1 - 0.0028 16.3 5.7 0.0037 15.9 5.7 1.3 1 0 0 1 1 1 1 Macoilin family CAF-1_p150 PF11600.8 ORY91497.1 - 0.11 12.2 34.5 0.019 14.7 14.3 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PocR PF10114.9 ORY91497.1 - 0.48 10.2 2.5 12 5.7 0.0 3.1 3 0 0 3 3 3 0 Sensory domain found in PocR Neur_chan_memb PF02932.16 ORY91497.1 - 3.2 7.7 6.6 1.3 9.0 4.1 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 ORY91497.1 - 7.1 5.9 18.5 13 5.1 18.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ERM PF00769.19 ORY91497.1 - 7.2 6.3 39.0 13 5.5 37.9 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Spc7 PF08317.11 ORY91497.1 - 7.7 5.3 21.5 0.43 9.4 5.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Mito_carr PF00153.27 ORY91498.1 - 4.5e-64 212.4 3.7 1.1e-20 73.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY91498.1 - 0.063 12.4 2.6 4.7 6.3 0.0 3.2 3 1 1 4 4 4 0 Gammaproteobacterial serine protease CAP_N PF01213.19 ORY91498.1 - 2.5 7.5 4.4 3.3 7.1 4.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Spt4 PF06093.13 ORY91499.1 - 2.6e-30 104.3 0.1 3.1e-30 104.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TackOD1 PF18551.1 ORY91499.1 - 0.069 12.8 0.5 0.085 12.5 0.5 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 mRNA_cap_C PF03919.15 ORY91499.1 - 0.15 12.7 0.0 0.17 12.5 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Mnd1 PF03962.15 ORY91502.1 - 3.7e-18 65.6 2.9 4.7e-18 65.2 0.4 2.2 2 0 0 2 2 2 1 Mnd1 HTH domain Sigma70_ner PF04546.13 ORY91502.1 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region FUR PF01475.19 ORY91502.1 - 0.056 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Ferric uptake regulator family Kinesin PF00225.23 ORY91503.1 - 2.8e-108 361.8 0.0 5.4e-108 360.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 ORY91503.1 - 3.9e-38 131.5 0.0 1.2e-37 129.9 0.0 2.0 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 ORY91503.1 - 2.6e-36 125.5 16.4 2.3e-31 109.3 1.5 3.6 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 ORY91503.1 - 1.2e-23 83.7 0.0 3e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 ORY91503.1 - 1.3e-11 44.9 0.0 3.1e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 PH domain FHA PF00498.26 ORY91503.1 - 1.7e-07 31.5 0.0 5.9e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.8 ORY91503.1 - 4e-06 27.2 0.0 1.7e-05 25.2 0.0 2.2 1 0 0 1 1 1 1 Kinesin protein 1B PH_11 PF15413.6 ORY91503.1 - 0.057 13.8 0.2 0.37 11.2 0.2 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain Yop-YscD_cpl PF16697.5 ORY91503.1 - 0.083 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DHR10 PF18595.1 ORY91503.1 - 0.45 10.6 19.7 0.61 10.1 6.6 2.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain dUTPase PF00692.19 ORY91504.1 - 3e-41 140.1 0.0 3.5e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 dUTPase Ccdc124 PF06244.12 ORY91505.1 - 3.4e-05 24.4 1.2 3.8e-05 24.3 1.2 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 ORY91505.1 - 0.0001 22.6 0.3 0.00017 21.9 0.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box EMG1 PF03587.14 ORY91506.1 - 2.9e-78 262.0 0.0 3.4e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase MFS_1 PF07690.16 ORY91508.1 - 6.7e-28 97.6 30.0 9.4e-28 97.1 30.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY91508.1 - 0.015 15.0 5.5 0.046 13.4 5.5 1.8 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF4199 PF13858.6 ORY91508.1 - 4 7.8 20.0 1.5 9.2 6.6 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF4199) Abhydrolase_3 PF07859.13 ORY91509.1 - 1.1e-17 64.6 0.2 5.7e-16 59.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY91509.1 - 5.9e-13 48.8 0.0 9.9e-08 31.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORY91509.1 - 0.00062 20.4 1.7 0.00089 19.9 1.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 ORY91509.1 - 0.0057 16.2 0.1 2.2 7.7 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase DLH PF01738.18 ORY91509.1 - 0.052 13.1 0.1 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.28 ORY91509.1 - 0.18 10.7 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.16 ORY91509.1 - 0.2 11.4 0.0 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FAD_binding_3 PF01494.19 ORY91510.1 - 3e-70 237.2 0.0 3.5e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 ORY91510.1 - 4.7e-15 56.0 0.0 2.3e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.27 ORY91510.1 - 1.5e-06 28.6 0.0 0.00011 22.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY91510.1 - 1.3e-05 25.0 0.1 3.5e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY91510.1 - 7.6e-05 22.1 0.0 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY91510.1 - 0.00058 18.8 0.0 0.0036 16.2 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 ORY91510.1 - 0.0023 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY91510.1 - 0.0024 17.1 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ORY91510.1 - 0.0062 15.3 0.0 0.098 11.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 ORY91510.1 - 0.0096 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 ORY91510.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY91510.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY91510.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY91510.1 - 0.15 11.1 0.0 0.4 9.7 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.18 ORY91511.1 - 5.9e-16 58.3 0.7 1.1e-15 57.4 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY91511.1 - 8e-05 22.7 8.8 0.00014 21.9 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carla_C4 PF01623.17 ORY91511.1 - 10 6.2 11.1 6.9 6.7 8.6 2.0 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein Cupin_2 PF07883.11 ORY91512.1 - 4.3e-09 36.0 0.0 8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Ccdc124 PF06244.12 ORY91513.1 - 3.9e-05 24.2 1.8 4.9e-05 23.9 1.8 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 ORY91513.1 - 0.00011 22.5 0.4 0.00017 22.0 0.4 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box Glyco_hydro_3_C PF01915.22 ORY91514.1 - 1.3e-53 182.0 0.0 1.9e-53 181.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY91514.1 - 4.9e-44 151.0 0.0 7.9e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY91514.1 - 5.1e-23 81.0 0.7 9.1e-23 80.2 0.7 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain ORC4_C PF14629.6 ORY91515.1 - 3.6e-24 85.4 0.3 3.3e-23 82.2 0.1 2.2 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 ORY91515.1 - 6.3e-07 29.9 1.8 7.6e-06 26.4 0.3 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 ORY91515.1 - 0.00027 21.4 0.0 0.0014 19.0 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY91515.1 - 0.00092 19.5 0.0 0.0025 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY91515.1 - 0.0025 17.8 0.0 0.0077 16.2 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Myc_N PF01056.18 ORY91515.1 - 3.3 7.5 22.5 0.29 11.0 2.0 2.4 1 1 1 2 2 2 0 Myc amino-terminal region Taxilin PF09728.9 ORY91517.1 - 0.0014 17.9 12.3 0.0014 17.9 12.3 3.0 3 0 0 3 3 3 1 Myosin-like coiled-coil protein Fez1 PF06818.15 ORY91517.1 - 0.0021 18.6 23.9 0.024 15.1 13.2 3.4 3 0 0 3 3 3 1 Fez1 DASH_Dam1 PF08653.10 ORY91517.1 - 0.034 13.9 2.4 0.22 11.3 0.2 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Phage_GP20 PF06810.11 ORY91517.1 - 0.32 10.8 11.7 2.3 8.0 0.2 4.0 3 1 0 3 3 3 0 Phage minor structural protein GP20 WD40_alt PF14077.6 ORY91517.1 - 0.51 10.2 2.3 8.1 6.4 0.0 3.3 3 0 0 3 3 3 0 Alternative WD40 repeat motif ZapB PF06005.12 ORY91517.1 - 0.85 10.1 40.7 0.1 13.0 7.4 5.3 5 0 0 5 5 5 0 Cell division protein ZapB Prefoldin_2 PF01920.20 ORY91517.1 - 1 9.3 0.0 1 9.3 0.0 3.9 3 1 1 4 4 3 0 Prefoldin subunit CK2S PF15011.6 ORY91517.1 - 1.1 9.1 7.7 6.5 6.6 2.9 3.1 3 1 1 4 4 4 0 Casein Kinase 2 substrate JIP_LZII PF16471.5 ORY91517.1 - 1.2 9.4 19.4 3.9 7.7 11.4 4.1 3 1 0 3 3 3 0 JNK-interacting protein leucine zipper II TMF_TATA_bd PF12325.8 ORY91517.1 - 1.7 8.9 33.4 0.6 10.4 0.4 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 ORY91517.1 - 3.4 7.8 46.8 0.2 11.7 5.2 4.9 5 1 0 5 5 4 0 TPR/MLP1/MLP2-like protein COG5 PF10392.9 ORY91517.1 - 8.3 6.6 8.4 12 6.1 1.2 2.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 HAUS-augmin3 PF14932.6 ORY91517.1 - 8.3 5.9 21.2 2.1 7.9 0.1 3.4 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 YabA PF06156.13 ORY91517.1 - 8.4 7.1 18.9 2.6 8.7 0.2 4.4 3 2 0 3 3 3 0 Initiation control protein YabA Rad51 PF08423.11 ORY91518.1 - 0.002 17.4 0.0 0.003 16.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 ORY91518.1 - 0.0027 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 KaiC Tht1 PF04163.12 ORY91518.1 - 0.1 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein SLX9 PF15341.6 ORY91519.1 - 2.5e-26 92.6 4.7 2.5e-26 92.6 4.7 1.9 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 MRPL52 PF18699.1 ORY91519.1 - 0.083 13.1 0.4 0.083 13.1 0.4 2.5 3 0 0 3 3 3 0 Mitoribosomal protein mL52 bZIP_1 PF00170.21 ORY91520.1 - 7e-06 26.0 7.1 7e-06 26.0 7.1 2.5 2 1 0 2 2 2 1 bZIP transcription factor PAP1 PF08601.10 ORY91520.1 - 0.0002 21.2 3.5 0.0002 21.2 3.5 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_2 PF07716.15 ORY91520.1 - 0.011 15.8 6.7 0.011 15.8 6.7 1.9 2 0 0 2 2 2 0 Basic region leucine zipper NRBF2 PF08961.10 ORY91520.1 - 9.7 5.7 9.4 0.12 11.9 0.5 2.0 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator Endostatin PF06482.11 ORY91521.1 - 2.6 7.4 8.8 4.4 6.7 8.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin WD40 PF00400.32 ORY91522.1 - 6.1e-12 45.9 13.9 1.9e-05 25.3 0.1 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 ORY91522.1 - 1.1e-10 41.6 0.4 1.6e-09 37.9 0.0 2.8 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex BUD22 PF09073.10 ORY91522.1 - 9.4 5.5 7.8 19 4.5 7.8 1.4 1 1 0 1 1 1 0 BUD22 F-box-like PF12937.7 ORY91523.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like DUF572 PF04502.13 ORY91525.1 - 1.1e-73 248.8 10.1 4.7e-73 246.7 10.1 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 ORY91525.1 - 0.032 14.2 1.9 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif SF3b1 PF08920.10 ORY91526.1 - 1.7e-32 112.4 0.0 5.1e-32 110.8 0.0 1.9 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 ORY91526.1 - 6.9e-13 48.8 2.6 0.00051 20.5 0.0 7.3 7 1 1 8 8 7 3 HEAT-like repeat HEAT_2 PF13646.6 ORY91526.1 - 1.8e-10 41.0 7.4 0.0019 18.6 0.2 7.3 3 2 4 7 7 7 3 HEAT repeats HEAT PF02985.22 ORY91526.1 - 3e-07 30.1 11.1 0.16 12.3 0.1 8.7 9 0 0 9 9 8 1 HEAT repeat Cnd1 PF12717.7 ORY91526.1 - 9.1e-07 29.0 10.8 0.043 13.9 0.0 6.4 8 0 0 8 8 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY91526.1 - 1.8e-06 28.4 3.5 0.38 11.4 0.0 5.4 6 0 0 6 6 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORY91526.1 - 2.8e-05 22.9 1.9 0.0064 15.1 0.1 3.4 3 1 0 3 3 3 1 Adaptin N terminal region UME PF08064.13 ORY91526.1 - 0.00018 21.4 2.2 0.16 11.9 0.0 4.9 5 2 2 7 7 7 1 UME (NUC010) domain CLASP_N PF12348.8 ORY91526.1 - 0.00034 20.3 2.4 0.24 10.9 0.1 3.4 3 1 0 3 3 3 2 CLASP N terminal Dopey_N PF04118.14 ORY91526.1 - 0.0016 17.6 1.8 0.06 12.5 0.0 3.3 3 0 0 3 3 3 1 Dopey, N-terminal NUC173 PF08161.12 ORY91526.1 - 0.0019 17.9 1.2 0.95 9.1 0.0 4.6 4 2 1 5 5 5 1 NUC173 domain DUF3385 PF11865.8 ORY91526.1 - 0.0023 17.9 1.6 3.6 7.5 0.1 4.4 4 2 1 5 5 5 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 ORY91526.1 - 0.013 14.6 0.0 14 4.6 0.0 3.8 3 1 0 4 4 4 0 RNAPII transcription regulator C-terminal UNC45-central PF11701.8 ORY91526.1 - 0.015 15.2 0.3 0.98 9.4 0.0 3.1 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central DUF3110 PF11360.8 ORY91526.1 - 0.056 13.7 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3110) Glyco_hydro_18 PF00704.28 ORY91527.1 - 8e-47 160.5 0.1 9.4e-47 160.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 ORY91527.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Tcf25 PF04910.14 ORY91528.1 - 1.3e-81 274.4 0.0 1.7e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Myc_N PF01056.18 ORY91528.1 - 0.055 13.4 6.5 0.13 12.1 6.5 1.5 1 0 0 1 1 1 0 Myc amino-terminal region RR_TM4-6 PF06459.12 ORY91528.1 - 8 6.2 8.1 20 4.9 8.1 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AP3D1 PF06375.11 ORY91528.1 - 8.7 6.6 10.3 22 5.2 4.8 3.7 4 0 0 4 4 4 0 AP-3 complex subunit delta-1 zf-RING_2 PF13639.6 ORY91530.1 - 2.1e-09 37.6 5.4 8e-09 35.7 5.4 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY91530.1 - 4.5e-09 36.5 2.7 8.2e-09 35.6 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY91530.1 - 2.4e-08 33.7 2.3 4.2e-08 32.9 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY91530.1 - 1.8e-06 27.8 2.5 4e-06 26.8 2.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY91530.1 - 2.5e-06 27.1 2.0 0.00057 19.6 0.3 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY91530.1 - 2.6e-06 27.2 7.2 2.6e-06 27.1 3.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY91530.1 - 7e-05 22.8 0.5 0.00014 21.8 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY91530.1 - 0.0006 19.7 0.8 0.0011 18.8 0.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY91530.1 - 0.0044 16.9 4.1 0.0093 15.8 4.1 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY91530.1 - 0.03 14.2 4.0 0.16 11.9 4.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY91530.1 - 0.28 11.4 6.7 8.3 6.7 6.7 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain YwiC PF14256.6 ORY91530.1 - 0.88 9.9 9.2 0.11 12.9 3.9 1.9 2 0 0 2 2 2 0 YwiC-like protein zf-P11 PF03854.14 ORY91530.1 - 9.2 6.0 10.5 0.2 11.4 1.5 2.5 3 0 0 3 3 3 0 P-11 zinc finger LPD13 PF18825.1 ORY91531.1 - 0.017 14.9 3.7 0.024 14.4 3.7 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 13 Pro_isomerase PF00160.21 ORY91532.1 - 9.3e-47 159.2 0.0 1.5e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 ORY91532.1 - 1.7e-07 30.8 1.9 0.016 15.3 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY91532.1 - 1.2e-05 24.9 2.0 0.09 12.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY91532.1 - 0.0023 17.6 2.4 0.068 12.9 0.2 2.7 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 ORY91532.1 - 0.071 13.8 5.1 1.6 9.4 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY91532.1 - 0.081 13.8 4.4 0.24 12.3 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY91532.1 - 0.24 11.7 1.7 10 6.7 0.3 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DSHCT PF08148.12 ORY91533.1 - 2.7e-52 176.8 1.3 5.4e-52 175.8 1.3 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 ORY91533.1 - 4.8e-35 120.3 0.0 9.7e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 ORY91533.1 - 3.4e-27 96.1 0.0 5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 ORY91533.1 - 2.5e-17 63.2 0.0 4.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY91533.1 - 9.9e-06 25.9 0.0 2.8e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY91533.1 - 1.3e-05 25.3 0.0 2.2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3516 PF12029.8 ORY91533.1 - 0.025 13.7 0.1 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) AATase PF07247.12 ORY91535.1 - 1e-11 44.1 0.0 2.9e-06 26.1 0.0 3.1 3 0 0 3 3 3 3 Alcohol acetyltransferase Condensation PF00668.20 ORY91535.1 - 4.2e-10 38.9 0.0 4.4e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.16 ORY91535.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Nucleoside_tran PF01733.18 ORY91536.1 - 1.6e-32 113.2 17.5 1.1e-30 107.1 4.5 3.5 3 1 0 3 3 3 2 Nucleoside transporter DUF5090 PF17009.5 ORY91536.1 - 2 8.4 6.5 16 5.4 1.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) S36_mt PF10937.8 ORY91538.1 - 3.4e-11 44.8 0.2 4.6e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial PPR_2 PF13041.6 ORY91539.1 - 7.2e-36 122.1 0.1 9.9e-13 48.1 0.0 10.5 10 2 2 12 12 12 4 PPR repeat family PPR PF01535.20 ORY91539.1 - 8.8e-27 91.4 17.0 9.6e-05 22.4 0.1 13.9 15 0 0 15 15 15 6 PPR repeat PPR_3 PF13812.6 ORY91539.1 - 3.2e-22 78.4 1.1 1.2e-09 38.1 0.0 7.4 6 1 2 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY91539.1 - 5.8e-16 57.9 4.8 0.00031 20.4 0.0 8.8 12 0 0 12 12 12 2 PPR repeat PPR_long PF17177.4 ORY91539.1 - 9.5e-12 44.7 2.8 2.3e-10 40.2 0.0 3.4 2 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 ORY91539.1 - 0.001 19.6 3.9 7.1 7.2 0.0 6.4 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY91539.1 - 0.0012 19.5 15.3 6.1 7.9 0.0 8.3 9 1 1 10 10 10 2 Tetratricopeptide repeat BTAD PF03704.17 ORY91539.1 - 0.0086 16.5 1.5 0.077 13.4 0.0 3.5 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_2 PF07719.17 ORY91539.1 - 0.15 12.2 8.0 79 3.7 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY91539.1 - 0.6 10.9 13.5 4.8 8.0 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Coa1 PF08695.10 ORY91540.1 - 6e-27 93.7 0.0 7.9e-27 93.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DNA_alkylation PF08713.11 ORY91541.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 DNA alkylation repair enzyme MFS_1 PF07690.16 ORY91542.1 - 3.6e-11 42.6 32.6 3.6e-11 42.6 32.6 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY91542.1 - 2.2e-07 30.7 4.4 2.2e-07 30.7 4.4 2.6 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORY91542.1 - 0.0016 17.4 8.7 0.0023 16.8 4.4 2.4 2 1 0 2 2 2 1 MFS_1 like family EHD_N PF16880.5 ORY91544.1 - 0.11 12.4 1.3 2.6 8.0 0.1 2.4 2 0 0 2 2 2 0 N-terminal EH-domain containing protein Fasciclin PF02469.22 ORY91545.1 - 1.2e-49 167.8 0.0 1.9e-16 60.4 0.0 7.9 6 3 0 6 6 6 5 Fasciclin domain DUF4381 PF14316.6 ORY91545.1 - 0.27 11.4 4.2 0.6 10.3 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FMO-like PF00743.19 ORY91546.1 - 2.6e-13 49.3 0.0 1.3e-11 43.7 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY91546.1 - 2.3e-10 40.2 0.0 2.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY91546.1 - 1.3e-08 35.0 0.0 3.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY91546.1 - 6.2e-08 32.8 1.8 7.3e-07 29.3 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 ORY91546.1 - 2.1e-07 30.8 1.0 0.00017 21.3 0.6 3.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORY91546.1 - 2.7e-06 26.8 0.0 0.00024 20.4 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY91546.1 - 0.0014 18.0 0.0 0.28 10.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY91546.1 - 0.0049 16.1 0.3 0.16 11.2 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ORY91546.1 - 0.017 15.7 1.6 0.056 14.0 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY91546.1 - 0.024 13.5 0.3 0.035 13.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 ORY91546.1 - 0.081 12.2 1.3 0.097 12.0 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY91546.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 ORY91546.1 - 0.14 11.4 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Cupin_5 PF06172.11 ORY91547.1 - 2.8e-38 131.3 0.0 3.3e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Ribosomal_L1 PF00687.21 ORY91548.1 - 2.9e-22 79.4 0.0 3.4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SelB-wing_1 PF09105.10 ORY91548.1 - 0.047 13.7 0.7 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DRMBL PF07522.14 ORY91549.1 - 8.3e-28 96.8 0.0 1.6e-27 95.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 ORY91549.1 - 0.00021 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain INCENP_N PF12178.8 ORY91549.1 - 0.035 14.1 0.6 0.035 14.1 0.6 1.7 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF305 PF03713.13 ORY91549.1 - 0.7 10.0 4.1 1.3 9.1 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF305) FMO-like PF00743.19 ORY91550.1 - 7.5e-14 51.0 0.0 1.3e-11 43.7 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY91550.1 - 8.9e-11 41.6 0.0 5.1e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY91550.1 - 4.5e-09 36.4 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY91550.1 - 1.2e-08 35.1 1.2 9.7e-07 28.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 ORY91550.1 - 4.3e-07 29.8 0.5 0.00017 21.3 0.7 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORY91550.1 - 4.6e-06 26.0 0.0 0.00036 19.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY91550.1 - 0.0021 17.4 0.1 0.59 9.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY91550.1 - 0.0093 15.2 0.4 0.27 10.5 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 ORY91550.1 - 0.013 16.1 1.0 0.063 13.8 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY91550.1 - 0.022 13.6 0.3 0.034 13.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 ORY91550.1 - 0.067 12.5 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY91550.1 - 0.083 12.0 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain SSF PF00474.17 ORY91551.1 - 5.7e-22 78.1 26.5 5.7e-22 78.1 26.5 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family zf-Nse PF11789.8 ORY91552.1 - 2.9e-13 49.4 0.1 4.6e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 ORY91552.1 - 0.00019 21.2 0.2 0.00034 20.4 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TT_ORF2 PF02957.15 ORY91554.1 - 0.27 12.1 0.2 0.27 12.1 0.2 3.3 3 1 1 4 4 4 0 TT viral ORF2 Pet127 PF08634.10 ORY91556.1 - 2.2e-99 332.4 0.1 3.3e-99 331.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Coprogen_oxidas PF01218.18 ORY91557.1 - 2.4e-128 427.0 0.1 2.8e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase PDT PF00800.18 ORY91558.1 - 5.5e-52 176.2 0.0 6.2e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Prephenate dehydratase adh_short_C2 PF13561.6 ORY91559.1 - 1.2e-66 224.6 0.2 1.4e-66 224.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY91559.1 - 9.5e-50 168.8 0.2 1.1e-49 168.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY91559.1 - 2.7e-07 30.7 0.5 4.1e-07 30.1 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY91559.1 - 0.021 14.7 0.5 0.044 13.7 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY91559.1 - 0.062 12.9 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AdoHcyase_NAD PF00670.21 ORY91559.1 - 0.091 12.8 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4111 PF13427.6 ORY91561.1 - 0.0039 17.3 0.0 0.0079 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) NTP_transf_2 PF01909.23 ORY91561.1 - 0.0065 16.7 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY91561.1 - 0.015 15.3 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase COA2 PF17051.5 ORY91561.1 - 0.023 14.7 0.4 0.11 12.5 0.3 1.9 1 1 1 2 2 2 0 Cytochrome C oxidase assembly factor 2 NatB_MDM20 PF09797.9 ORY91561.1 - 0.026 13.5 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Peptidase_M48 PF01435.18 ORY91561.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Zn_clus PF00172.18 ORY91562.1 - 5.7e-07 29.6 11.6 9.2e-07 28.9 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY91562.1 - 0.038 13.0 0.0 0.085 11.9 0.0 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF1754 PF08555.10 ORY91563.1 - 6.5e-12 46.1 9.5 6.5e-12 46.1 9.5 1.6 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) TMEM215 PF15746.5 ORY91563.1 - 0.083 12.3 2.8 0.092 12.2 2.8 1.1 1 0 0 1 1 1 0 TMEM215 family Raftlin PF15250.6 ORY91563.1 - 0.36 9.5 5.5 0.4 9.4 5.5 1.0 1 0 0 1 1 1 0 Raftlin Dsh_C PF12316.8 ORY91563.1 - 0.61 10.5 8.4 0.77 10.1 8.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4674 PF15719.5 ORY91563.1 - 1.2 9.2 8.4 1.5 8.8 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) TT_ORF2 PF02957.15 ORY91563.1 - 1.9 9.4 6.0 0.85 10.5 3.3 1.6 1 1 1 2 2 2 0 TT viral ORF2 DIOX_N PF14226.6 ORY91564.1 - 2.4e-30 105.7 0.0 3.7e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY91564.1 - 8.4e-22 77.6 0.0 1.5e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LEAP-2 PF07359.11 ORY91564.1 - 0.076 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Aminotran_4 PF01063.19 ORY91565.1 - 5e-22 78.9 0.0 7.2e-22 78.3 0.0 1.3 1 1 0 1 1 1 1 Amino-transferase class IV Mpv17_PMP22 PF04117.12 ORY91567.1 - 9.3e-11 41.8 2.6 1.1e-10 41.6 0.6 2.2 2 1 0 2 2 2 1 Mpv17 / PMP22 family PAP2 PF01569.21 ORY91569.1 - 1.8e-09 37.5 13.2 2.2e-08 34.0 13.2 2.5 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 ORY91569.1 - 0.0012 19.0 0.4 0.1 12.7 0.0 2.4 2 1 0 2 2 2 2 Divergent PAP2 family SNF2_N PF00176.23 ORY91570.1 - 1.3e-73 247.7 0.0 1.9e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY91570.1 - 4.8e-15 55.9 0.0 1.4e-14 54.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.11 ORY91570.1 - 3.1e-11 43.1 0.0 7.8e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.15 ORY91570.1 - 1.4e-06 28.4 0.0 0.0011 18.9 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 ORY91570.1 - 3.1e-06 26.9 5.0 5.5e-06 26.1 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY91570.1 - 0.00015 21.6 6.1 0.00028 20.8 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY91570.1 - 0.00016 21.5 4.5 0.00028 20.7 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY91570.1 - 0.0007 19.4 5.9 0.0015 18.4 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY91570.1 - 0.001 19.3 5.5 0.0019 18.5 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.29 ORY91570.1 - 0.0056 16.5 0.4 0.083 12.7 0.4 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 ORY91570.1 - 0.28 10.3 1.3 0.47 9.6 0.0 1.9 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 zf-RING_UBOX PF13445.6 ORY91570.1 - 1.4 9.0 6.4 3.1 7.9 6.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Cullin PF00888.22 ORY91571.1 - 1.5e-24 86.6 0.1 2.3e-24 86.0 0.1 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 ORY91571.1 - 3.7e-16 59.4 0.0 1.1e-15 57.9 0.0 1.9 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 HTH_DeoR PF08220.12 ORY91571.1 - 0.062 13.1 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain CAP PF00188.26 ORY91572.1 - 1.9e-23 83.7 2.0 2.7e-23 83.2 2.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.16 ORY91573.1 - 1e-29 103.6 41.7 1.4e-29 103.1 41.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY91573.1 - 0.0015 17.9 8.0 0.0015 17.9 8.0 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ORY91573.1 - 0.0065 14.8 1.1 0.0065 14.8 1.1 2.8 2 2 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family HLH PF00010.26 ORY91574.1 - 2.9e-12 46.4 0.3 4.7e-12 45.7 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AA_permease_2 PF13520.6 ORY91575.1 - 7.6e-41 140.3 50.3 9.2e-41 140.0 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY91575.1 - 3e-16 59.1 41.2 4e-16 58.7 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4245 PF14030.6 ORY91575.1 - 0.45 10.5 0.1 0.45 10.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4245) DUF3464 PF11947.8 ORY91575.1 - 1.6 8.5 7.3 0.57 9.9 2.9 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Acyl-CoA_dh_1 PF00441.24 ORY91576.1 - 4.9e-43 146.9 3.9 7e-43 146.4 3.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY91576.1 - 8.3e-26 90.9 0.1 2e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY91576.1 - 2.9e-20 72.3 0.0 5.7e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY91576.1 - 2e-17 63.7 0.4 3e-17 63.1 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 ORY91577.1 - 3.6e-05 23.8 10.8 6.2e-05 23.0 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Erf4 PF10256.9 ORY91578.1 - 1.4e-30 105.7 0.0 1.9e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Sugar_tr PF00083.24 ORY91580.1 - 5.4e-65 220.0 23.5 6e-63 213.3 23.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY91580.1 - 2e-22 79.6 35.0 2.4e-21 76.1 26.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY91580.1 - 3.4e-05 22.6 4.5 3.4e-05 22.6 4.5 3.6 3 1 0 4 4 4 2 MFS/sugar transport protein Wzz PF02706.15 ORY91581.1 - 0.056 13.7 0.3 0.065 13.5 0.3 1.2 1 0 0 1 1 1 0 Chain length determinant protein Actin PF00022.19 ORY91582.1 - 5e-38 130.8 0.0 3.6e-36 124.6 0.0 3.4 2 2 1 3 3 3 1 Actin GvpG PF05120.12 ORY91582.1 - 0.19 11.8 2.0 5.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Gas vesicle protein G Catalase PF00199.19 ORY91583.1 - 1.6e-187 623.3 0.2 2e-187 623.0 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 ORY91583.1 - 1.3e-16 60.6 0.0 4.3e-16 58.9 0.0 2.0 1 0 0 1 1 1 1 Catalase-related immune-responsive SMC_N PF02463.19 ORY91584.1 - 1e-61 208.2 1.8 1.4e-61 207.7 1.8 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY91584.1 - 1.6e-29 102.6 0.0 5.3e-29 100.9 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY91584.1 - 6.7e-16 59.0 2.2 1.1e-06 28.7 0.1 3.9 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY91584.1 - 4.6e-15 56.2 28.7 3e-12 46.9 0.4 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 ORY91584.1 - 3.7e-11 43.9 38.7 3.7e-11 43.9 38.7 6.6 2 2 0 2 2 1 1 AAA domain LPP PF04728.13 ORY91584.1 - 3.3e-05 24.2 14.4 0.011 16.1 1.4 4.7 3 1 1 4 4 4 2 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 ORY91584.1 - 0.0011 19.0 12.4 0.0011 19.0 12.4 8.6 3 3 6 9 9 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.6 ORY91584.1 - 0.0025 17.5 0.0 0.0066 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 ORY91584.1 - 0.0053 16.1 12.8 0.0053 16.1 12.8 7.0 2 2 3 7 7 7 2 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 ORY91584.1 - 0.012 15.8 4.4 0.012 15.8 4.4 8.8 3 2 6 9 9 8 0 Seryl-tRNA synthetase N-terminal domain MbeD_MobD PF04899.12 ORY91584.1 - 0.66 10.1 10.0 1.4 9.0 1.1 4.2 3 0 0 3 3 3 0 MbeD/MobD like Leucyl-specific PF14795.6 ORY91584.1 - 2.4 8.3 9.2 18 5.5 0.0 4.5 4 0 0 4 4 4 0 Leucine-tRNA synthetase-specific domain Aa_trans PF01490.18 ORY91585.1 - 1.2e-72 244.9 17.2 1.4e-72 244.7 17.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY91585.1 - 0.0011 18.1 9.2 0.0011 18.1 9.2 2.2 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Med13_C PF06333.12 ORY91585.1 - 3.6 6.8 6.8 5.8 6.1 6.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain PAS_9 PF13426.7 ORY91586.1 - 7.6e-18 64.7 0.0 7.7e-17 61.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 ORY91586.1 - 2.7e-05 24.4 0.0 0.0001 22.5 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 ORY91586.1 - 0.00016 21.7 0.1 0.00081 19.4 0.0 2.3 3 0 0 3 3 3 1 PAS fold RGS PF00615.19 ORY91586.1 - 0.018 15.3 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 Regulator of G protein signaling domain Abhydrolase_1 PF00561.20 ORY91587.1 - 1.2e-11 44.7 0.0 4.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY91587.1 - 1.5e-09 37.5 0.0 4.9e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY91587.1 - 1.8e-05 25.4 0.2 3.2e-05 24.6 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORY91587.1 - 0.027 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 ORY91587.1 - 0.095 12.3 0.0 14 5.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 ORY91588.1 - 6.2e-07 29.3 0.0 0.0032 17.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY91588.1 - 9.6e-06 25.0 0.0 0.0052 16.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY91588.1 - 0.0064 17.1 0.0 0.69 10.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 ORY91588.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PI-PLC-C1 PF16670.5 ORY91589.1 - 0.0022 17.2 1.1 0.61 9.1 0.0 2.8 1 1 2 3 3 3 2 Phosphoinositide phospholipase C, Ca2+-dependent PI-PLC-X PF00388.19 ORY91589.1 - 0.0093 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ccdc124 PF06244.12 ORY91591.1 - 7.5e-05 23.3 1.3 9.1e-05 23.0 1.3 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_2 PF09011.10 ORY91591.1 - 0.00062 20.3 1.7 0.00074 20.1 1.7 1.1 1 0 0 1 1 1 1 HMG-box domain YqzE PF14038.6 ORY91591.1 - 1.2 9.2 6.2 0.16 12.0 1.9 1.7 1 1 1 2 2 2 0 YqzE-like protein Ferric_reduct PF01794.19 ORY91592.1 - 1.9e-20 73.2 11.6 1.9e-20 73.2 11.6 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY91592.1 - 2.1e-13 50.3 0.0 1.8e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY91592.1 - 0.00012 22.2 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 ORY91592.1 - 0.068 13.7 13.7 0.079 13.5 1.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) HMG_box PF00505.19 ORY91593.1 - 0.004 17.6 0.9 0.0066 16.8 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box YABBY PF04690.13 ORY91593.1 - 0.028 15.0 1.3 0.031 14.9 1.3 1.1 1 0 0 1 1 1 0 YABBY protein 60KD_IMP PF02096.20 ORY91593.1 - 2 8.3 4.3 2.4 8.0 4.3 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein MRP-S34 PF16053.5 ORY91594.1 - 0.00042 20.0 0.8 0.0013 18.3 0.1 2.0 1 1 1 2 2 2 1 Mitochondrial 28S ribosomal protein S34 Chitin_synth_1 PF01644.17 ORY91595.1 - 4.9e-69 231.5 0.0 7.5e-69 230.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY91595.1 - 3.6e-26 90.9 0.0 7.9e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY91595.1 - 3.4e-25 88.7 0.1 9.7e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY91595.1 - 2e-06 27.9 0.1 2e-06 27.9 0.1 3.0 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Pex24p PF06398.11 ORY91595.1 - 0.032 13.2 0.1 0.086 11.8 0.1 1.7 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Promethin PF16015.5 ORY91596.1 - 8.1e-13 48.2 10.0 1.1e-12 47.8 10.0 1.1 1 0 0 1 1 1 1 Promethin LptF_LptG PF03739.14 ORY91596.1 - 0.029 13.2 1.8 0.033 13.0 1.8 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF2207 PF09972.9 ORY91596.1 - 1.7 7.3 4.2 2.6 6.7 4.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Hydrolase_4 PF12146.8 ORY91597.1 - 9e-37 126.6 0.0 2.9e-36 124.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY91597.1 - 2.6e-10 41.3 0.0 4.2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY91597.1 - 3.1e-08 33.6 0.6 0.0002 21.1 0.6 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 ORY91597.1 - 5.4e-05 22.9 0.0 0.0032 17.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 ORY91597.1 - 0.00026 20.5 0.2 0.27 10.7 0.1 3.0 3 0 0 3 3 3 2 Prolyl oligopeptidase family Pectinesterase PF01095.19 ORY91598.1 - 6.3e-26 90.8 0.3 5e-21 74.7 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase SNF2_N PF00176.23 ORY91599.1 - 3.7e-64 216.6 1.4 5.8e-64 216.0 0.3 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 ORY91599.1 - 1.1e-47 161.7 18.5 1.1e-47 161.7 18.5 5.2 4 1 1 5 5 5 1 DNA-binding domain Helicase_C PF00271.31 ORY91599.1 - 1.4e-17 64.1 0.1 6.3e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY91599.1 - 1.7e-06 28.1 0.3 8.8e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY91599.1 - 0.00073 18.8 0.0 0.00073 18.8 0.0 3.2 4 0 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DIOX_N PF14226.6 ORY91601.1 - 2.4e-22 79.9 0.2 3.9e-22 79.2 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY91601.1 - 2.4e-16 60.1 0.0 4.1e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FYRN PF05964.14 ORY91602.1 - 4.6e-17 61.6 0.2 7.2e-17 61.0 0.2 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY91602.1 - 2.5e-15 56.4 0.0 4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus Zip PF02535.22 ORY91603.1 - 6.8e-35 120.8 23.8 2.6e-25 89.4 12.9 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter HORMA PF02301.18 ORY91604.1 - 5.3e-06 26.2 0.1 3.8e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 HORMA domain Acetyltransf_13 PF13880.6 ORY91605.1 - 2e-23 82.1 0.0 3.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 ORY91605.1 - 5.2e-06 26.2 0.3 9.5e-06 25.3 0.3 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF4210 PF13915.6 ORY91606.1 - 9.4e-26 90.2 0.1 2.3e-25 88.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 ORY91606.1 - 8e-16 57.9 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis ICL PF00463.21 ORY91607.1 - 7.9e-263 872.7 3.3 8.9e-263 872.5 3.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORY91607.1 - 2.8e-07 30.2 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PLDc PF00614.22 ORY91608.1 - 1.4e-14 53.5 0.6 3.4e-06 27.0 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 ORY91608.1 - 1.1e-13 51.2 0.0 4.5e-07 29.8 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.24 ORY91608.1 - 3.5e-11 43.1 0.5 2.3e-10 40.5 0.1 2.5 2 0 0 2 2 2 1 PX domain Usp PF00582.26 ORY91609.1 - 3e-24 86.1 0.8 1.3e-23 84.0 0.1 2.1 2 0 0 2 2 2 1 Universal stress protein family SPX PF03105.19 ORY91610.1 - 1.1 9.1 8.3 1.2 9.0 8.3 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 ORY91610.1 - 1.4 7.4 10.3 1.8 7.1 10.3 1.0 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 ORY91610.1 - 3.6 6.3 10.8 4.4 6.0 10.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GATA PF00320.27 ORY91612.1 - 1.9e-12 46.6 2.7 3.5e-12 45.7 2.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PPP4R2 PF09184.11 ORY91612.1 - 2.1 7.9 4.4 35 3.9 2.4 2.5 2 1 0 2 2 2 0 PPP4R2 Sulfate_transp PF00916.20 ORY91614.1 - 1.7e-111 372.7 21.9 2.1e-111 372.4 21.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY91614.1 - 2.8e-08 33.4 0.0 5.4e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY91614.1 - 0.00016 21.9 0.4 0.0005 20.4 0.1 1.9 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 ORY91614.1 - 0.0014 19.0 1.4 0.0014 19.0 1.4 3.1 2 2 1 3 3 3 2 Molybdate transporter of MFS superfamily Ima1_N PF09779.9 ORY91617.1 - 4.5e-22 79.4 4.7 4.7e-21 76.1 4.7 2.1 1 1 0 1 1 1 1 Ima1 N-terminal domain TF_Zn_Ribbon PF08271.12 ORY91617.1 - 0.012 15.1 1.8 0.58 9.7 0.0 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding Nudix_N_2 PF14803.6 ORY91617.1 - 0.094 12.6 4.5 0.84 9.6 0.1 3.0 3 0 0 3 3 3 0 Nudix N-terminal zf-Di19 PF05605.12 ORY91617.1 - 0.28 11.5 2.6 10 6.5 0.1 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_10 PF10058.9 ORY91617.1 - 4.4 7.1 6.2 5.5 6.8 0.0 2.8 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein IBR PF01485.21 ORY91619.1 - 2.2e-10 40.6 20.1 1.9e-05 24.8 5.2 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 ORY91619.1 - 0.018 15.4 4.2 0.018 15.4 4.2 4.2 2 1 1 3 3 3 0 Ring finger domain DUF4670 PF15709.5 ORY91619.1 - 3.6 6.8 17.9 5.2 6.3 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) zf-RING_2 PF13639.6 ORY91620.1 - 2.1e-11 43.9 7.2 3e-11 43.5 7.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY91620.1 - 3.4e-07 30.4 6.1 6.8e-07 29.5 6.1 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY91620.1 - 3.9e-07 29.8 6.7 5.6e-07 29.3 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY91620.1 - 4.9e-07 29.4 4.3 7.5e-07 28.8 4.3 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY91620.1 - 0.00017 21.4 5.2 0.00024 20.9 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY91620.1 - 0.0016 18.4 3.2 0.0023 17.9 3.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY91620.1 - 0.0027 17.5 2.5 0.0039 17.0 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY91620.1 - 0.017 15.1 4.7 0.05 13.7 4.7 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORY91620.1 - 0.042 13.7 2.9 0.072 12.9 2.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 ORY91620.1 - 0.071 12.7 4.0 0.12 12.0 4.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORY91620.1 - 0.19 11.9 2.5 0.3 11.3 2.5 1.3 1 0 0 1 1 1 0 RING-variant domain Fungal_trans PF04082.18 ORY91621.1 - 5.8e-17 61.6 0.2 9.3e-17 60.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_jaz PF12171.8 ORY91621.1 - 0.031 14.5 0.3 0.055 13.8 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY91621.1 - 0.18 12.7 1.8 0.51 11.3 1.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 ORY91621.1 - 0.19 12.1 0.7 0.38 11.2 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORY91621.1 - 0.24 11.9 2.1 0.56 10.8 2.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Amino_oxidase PF01593.24 ORY91622.1 - 2.6e-45 155.6 0.2 3.4e-44 151.9 0.2 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY91622.1 - 1.6e-11 44.2 0.3 7.6e-11 42.1 0.5 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY91622.1 - 1.3e-08 34.6 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY91622.1 - 8.5e-07 28.4 0.6 1.4e-06 27.7 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY91622.1 - 9.8e-07 28.7 0.0 2.1e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY91622.1 - 7.3e-06 25.4 0.2 1.7e-05 24.2 0.1 1.6 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 ORY91622.1 - 1.4e-05 24.0 0.1 2.6e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ORY91622.1 - 3.1e-05 23.3 0.1 4.9e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ORY91622.1 - 8.2e-05 22.0 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY91622.1 - 0.00024 20.3 0.1 0.00049 19.3 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY91622.1 - 0.0033 17.9 0.1 0.0076 16.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY91622.1 - 0.0067 15.7 0.1 0.012 14.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY91622.1 - 0.06 12.6 0.0 0.93 8.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 ORY91623.1 - 2.7e-52 178.1 50.4 3.2e-52 177.8 50.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY91623.1 - 2.3e-29 102.3 39.5 3.3e-29 101.8 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease T3SchapCesA PF11439.8 ORY91624.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA ParBc PF02195.18 ORY91626.1 - 2.6e-06 27.6 0.0 3.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain Peptidase_M22 PF00814.25 ORY91627.1 - 1.4e-78 264.4 0.0 8.1e-57 193.0 0.0 2.1 2 0 0 2 2 2 2 Glycoprotease family PAC3 PF10178.9 ORY91628.1 - 0.015 15.4 0.0 0.21 11.8 0.0 2.2 1 1 0 1 1 1 0 Proteasome assembly chaperone 3 Asp PF00026.23 ORY91629.1 - 1.7e-80 270.8 5.8 2.1e-80 270.5 5.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY91629.1 - 1.4e-09 38.4 8.2 8.4e-08 32.6 3.5 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Vta1 PF04652.16 ORY91631.1 - 2e-47 160.8 0.8 3.2e-47 160.1 0.8 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 ORY91631.1 - 1.2e-15 56.8 0.1 1.2e-15 56.8 0.1 2.2 3 0 0 3 3 3 1 Vta1 C-terminal domain HA2 PF04408.23 ORY91632.1 - 1e-15 58.0 0.3 6e-15 55.4 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY91632.1 - 3.2e-13 50.0 0.1 8.3e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY91632.1 - 7.9e-12 45.3 0.0 1.7e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 ORY91632.1 - 6.4e-09 36.1 0.0 2.1e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 ORY91632.1 - 1.6e-08 34.9 0.0 4.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY91632.1 - 0.0087 16.6 0.0 0.034 14.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_19 PF13245.6 ORY91632.1 - 0.014 15.7 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY91632.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 ORY91632.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ORY91632.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Glyco_transf_8 PF01501.20 ORY91634.1 - 4.6e-18 65.7 0.1 6.4e-18 65.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Get5_bdg PF16843.5 ORY91634.1 - 0.17 11.4 0.8 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein eIF2A PF08662.11 ORY91635.1 - 9.3e-40 136.6 1.5 5.7e-36 124.2 0.5 4.8 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ORY91635.1 - 0.0064 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 ORY91635.1 - 3 8.9 5.3 16 6.6 0.0 4.5 6 0 0 6 6 6 0 WD domain, G-beta repeat DUF1741 PF08427.10 ORY91636.1 - 7.8e-44 150.1 0.0 1.7e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Ribosomal_60s PF00428.19 ORY91636.1 - 0.31 11.6 8.0 34 5.1 0.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein RPAP1_N PF08621.10 ORY91637.1 - 1 9.2 6.2 0.13 12.1 1.0 2.3 2 1 0 2 2 2 0 RPAP1-like, N-terminal Fungal_trans PF04082.18 ORY91638.1 - 5.6e-14 51.8 1.2 8.5e-14 51.2 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.24 ORY91639.1 - 2.5e-37 129.2 0.5 7.6e-37 127.7 0.5 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY91639.1 - 3.7e-11 43.1 0.2 2.2e-10 40.6 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY91639.1 - 2e-06 27.5 0.1 3e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY91639.1 - 2.9e-06 26.7 0.4 4.8e-06 25.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY91639.1 - 3.7e-06 26.8 0.1 9.3e-06 25.4 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY91639.1 - 4.7e-05 22.3 0.1 0.0001 21.2 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 ORY91639.1 - 0.00014 21.1 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY91639.1 - 0.00026 20.3 0.1 0.00043 19.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ORY91639.1 - 0.00028 20.2 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY91639.1 - 0.0017 17.5 0.1 0.0028 16.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY91639.1 - 0.072 13.7 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY91639.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 ORY91639.1 - 0.12 11.7 0.2 0.61 9.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 ORY91640.1 - 9.9e-55 186.1 57.6 1.2e-54 185.8 57.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY91640.1 - 3.9e-22 78.5 52.0 7.1e-22 77.6 51.9 1.4 1 1 0 1 1 1 1 Amino acid permease PspA_IM30 PF04012.12 ORY91641.1 - 0.36 10.4 4.8 0.14 11.7 1.7 1.8 2 1 0 2 2 2 0 PspA/IM30 family PEX11 PF05648.14 ORY91643.1 - 1.1e-61 208.2 0.7 1.2e-61 208.1 0.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Pyrid_oxidase_2 PF13883.6 ORY91644.1 - 3.8e-19 69.3 0.0 4.8e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ABC1 PF03109.16 ORY91645.1 - 5.9e-23 81.3 0.0 1.6e-14 54.1 0.0 2.5 2 0 0 2 2 2 2 ABC1 family RRM_1 PF00076.22 ORY91646.1 - 1.2e-22 79.5 0.0 3e-10 39.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY91646.1 - 8.2e-09 35.1 0.0 0.00085 18.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY91646.1 - 0.00015 21.5 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 ORY91646.1 - 0.0098 15.9 0.1 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 Limkain b1 PPR_2 PF13041.6 ORY91647.1 - 1.5e-37 127.6 0.0 1.5e-08 34.7 0.0 11.1 10 2 2 12 12 12 7 PPR repeat family PPR_3 PF13812.6 ORY91647.1 - 9.5e-21 73.7 0.0 1.6e-08 34.5 0.0 7.5 6 2 2 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.20 ORY91647.1 - 8.1e-18 63.4 20.1 0.00031 20.8 0.0 9.8 12 0 0 12 12 12 5 PPR repeat PPR_1 PF12854.7 ORY91647.1 - 2.3e-15 56.0 2.8 0.00093 18.9 0.0 7.6 7 0 0 7 7 7 5 PPR repeat PPR_long PF17177.4 ORY91647.1 - 7.6e-13 48.3 0.0 4.6e-06 26.1 0.0 4.2 3 2 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP DUF3368 PF11848.8 ORY91647.1 - 0.033 14.0 1.3 1.1e+02 2.6 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3368) CENP-R PF06729.12 ORY91647.1 - 0.08 12.9 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Kinetochore component, CENP-R Prenyltrans PF00432.21 ORY91648.1 - 6.1e-57 189.0 13.7 5.4e-13 48.4 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ORY91648.1 - 0.0096 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain CcmD PF04995.14 ORY91648.1 - 3.8 7.7 7.3 0.81 9.8 1.4 2.6 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SecE PF00584.20 ORY91649.1 - 3.5e-14 52.4 0.0 4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF5547 PF17701.1 ORY91649.1 - 0.099 12.5 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5547) Ferric_reduct PF01794.19 ORY91650.1 - 8.6e-20 71.1 13.8 8.6e-20 71.1 13.8 3.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY91650.1 - 3.4e-14 53.3 0.0 8.3e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY91650.1 - 3.9e-13 49.4 0.0 2.9e-12 46.6 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY91650.1 - 0.019 15.6 0.0 0.32 11.7 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 ORY91650.1 - 0.093 13.3 18.3 0.041 14.4 2.9 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) DUF5090 PF17009.5 ORY91650.1 - 6.4 6.7 12.6 16 5.4 12.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Spb1_C PF07780.12 ORY91651.1 - 5.9e-71 238.4 17.8 5.9e-71 238.4 17.8 3.7 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 ORY91651.1 - 5.7e-55 186.2 0.0 9.4e-55 185.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 ORY91651.1 - 2.2e-44 151.2 4.4 2.2e-44 151.2 4.4 5.9 4 1 2 7 7 7 1 Domain of unknown function (DUF3381) PhyH PF05721.13 ORY91652.1 - 0.00028 21.2 0.0 0.00066 20.0 0.0 1.6 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORY91652.1 - 0.0015 18.9 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase ANAPC10 PF03256.16 ORY91653.1 - 1.8e-56 190.7 0.0 2e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 ORY91653.1 - 0.0072 16.4 0.5 0.0099 16.0 0.5 1.3 1 1 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 ORY91653.1 - 0.0091 16.0 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain Rsm22 PF09243.10 ORY91654.1 - 2.3e-52 178.0 0.0 8.1e-51 172.9 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 zf-Tim10_DDP PF02953.15 ORY91655.1 - 2.7e-22 78.2 1.5 3.5e-22 77.8 1.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PBP1_TM PF14812.6 ORY91656.1 - 0.064 13.6 1.0 0.4 11.1 0.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5082 PF16888.5 ORY91657.1 - 0.0039 17.5 2.1 0.005 17.1 0.6 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Cor1 PF04803.12 ORY91657.1 - 0.0095 16.1 2.8 0.015 15.5 2.8 1.3 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region MbeB_N PF04837.12 ORY91657.1 - 0.027 14.8 3.1 0.027 14.8 3.1 2.5 1 1 1 2 2 2 0 MbeB-like, N-term conserved region Phage_NinH PF06322.11 ORY91657.1 - 0.1 12.5 0.1 0.22 11.4 0.1 1.6 2 0 0 2 2 1 0 Phage NinH protein Atg14 PF10186.9 ORY91657.1 - 0.12 11.4 6.5 0.17 10.9 6.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prominin PF05478.11 ORY91657.1 - 0.14 10.1 2.4 0.16 9.9 2.4 1.1 1 0 0 1 1 1 0 Prominin Cep57_CLD_2 PF14197.6 ORY91657.1 - 0.15 12.1 8.8 1.8 8.7 8.8 2.3 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 OmpH PF03938.14 ORY91657.1 - 0.18 12.2 3.8 0.29 11.4 3.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IZUMO PF15005.6 ORY91657.1 - 0.28 11.7 3.7 3.3 8.2 3.7 2.0 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated MetOD2 PF18548.1 ORY91657.1 - 0.35 11.0 5.5 0.11 12.6 1.0 2.5 2 1 1 3 3 3 0 Metanogen output domain 2 GBP_C PF02841.14 ORY91657.1 - 0.41 10.0 11.1 0.56 9.6 11.1 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain UPF0242 PF06785.11 ORY91657.1 - 0.86 9.7 10.2 0.67 10.0 8.7 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 ORY91657.1 - 1.8 7.4 3.3 2.1 7.2 3.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mog1 PF04603.12 ORY91657.1 - 2.1 8.7 5.8 1.3 9.4 3.2 1.8 1 1 1 2 2 2 0 Ran-interacting Mog1 protein CENP-Q PF13094.6 ORY91657.1 - 2.5 8.3 16.5 19 5.4 16.0 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMPIT PF07851.13 ORY91657.1 - 3.1 7.0 5.4 4.1 6.5 5.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein 2OG-FeII_Oxy_2 PF13532.6 ORY91658.1 - 5.5e-17 62.6 0.0 1.1e-16 61.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 ORY91659.1 - 7.5e-39 131.0 22.0 1.9e-09 38.0 0.4 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY91659.1 - 6e-21 74.6 0.8 0.00086 19.6 0.4 6.6 3 2 5 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY91659.1 - 8e-08 32.4 0.0 0.2 11.5 0.0 4.0 3 2 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 ORY91659.1 - 3.6e-05 23.6 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 ORY91659.1 - 0.00041 19.4 0.1 2.4 7.1 0.0 3.8 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY91659.1 - 0.022 14.1 0.0 0.17 11.2 0.0 2.4 2 1 1 3 3 3 0 WD40-like domain Nbas_N PF15492.6 ORY91659.1 - 0.031 13.6 0.3 14 4.9 0.0 3.3 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 ORY91659.1 - 0.045 12.4 1.7 6.2 5.3 0.0 2.9 2 2 1 3 3 3 0 Nucleoporin Nup120/160 DUF1688 PF07958.11 ORY91661.1 - 7.3e-157 522.4 0.0 8.3e-157 522.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Methyltransf_34 PF11312.8 ORY91662.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase GalKase_gal_bdg PF10509.9 ORY91663.1 - 5.6e-22 77.0 0.0 9.4e-22 76.3 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 ORY91663.1 - 5.1e-14 52.4 0.0 1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 ORY91663.1 - 3.7e-13 49.5 0.5 9.5e-13 48.2 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain UPF0220 PF05255.11 ORY91664.1 - 7.9e-57 191.4 0.1 9.3e-57 191.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) SHIPPO-rpt PF07004.12 ORY91664.1 - 0.18 12.8 0.1 17 6.5 0.0 2.4 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat PrgI PF12666.7 ORY91664.1 - 0.68 10.7 0.0 0.68 10.7 0.0 2.3 2 1 0 2 2 2 0 PrgI family protein Lyase_1 PF00206.20 ORY91665.1 - 3.2e-114 381.5 0.0 4e-114 381.2 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 ORY91665.1 - 2.1e-18 66.4 0.0 2.1e-18 66.4 0.0 2.2 3 0 0 3 3 3 1 Fumarase C C-terminus FmrO PF07091.11 ORY91665.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ADH_N PF08240.12 ORY91665.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain SUR7 PF06687.12 ORY91666.1 - 9e-21 74.5 15.9 1.2e-20 74.0 15.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family PIG-Y PF15159.6 ORY91667.1 - 3.7e-16 59.8 4.3 4.4e-16 59.6 4.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Zn_clus PF00172.18 ORY91668.1 - 1e-06 28.8 8.5 1.6e-06 28.2 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY91668.1 - 9.8e-06 24.8 2.4 0.074 12.1 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Acyltransferase PF01553.21 ORY91669.1 - 7e-20 71.0 0.0 1.5e-19 69.9 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 ORY91669.1 - 2.3e-07 30.8 1.6 0.0002 21.4 0.5 2.4 1 1 1 2 2 2 2 Acyltransferase C-terminus MHCassoc_trimer PF08831.10 ORY91669.1 - 0.00074 19.5 4.4 0.022 14.7 0.2 2.7 3 0 0 3 3 3 2 Class II MHC-associated invariant chain trimerisation domain AMPKBI PF04739.15 ORY91670.1 - 1.2e-22 80.0 0.0 2.9e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 ORY91670.1 - 4.2e-22 78.2 0.0 1.3e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Acyltransferase PF01553.21 ORY91672.1 - 1.5e-18 66.7 0.0 2.3e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY91672.1 - 3.5e-09 36.6 0.1 4.4e-06 26.7 0.0 2.8 2 0 0 2 2 2 2 Acyltransferase C-terminus Peptidase_M43 PF05572.13 ORY91673.1 - 1.2e-11 44.8 0.8 3.9e-11 43.1 0.8 1.8 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 ORY91673.1 - 0.044 14.3 0.6 1.5 9.4 0.2 2.6 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY91673.1 - 0.056 13.6 0.8 0.098 12.8 0.3 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 ORY91673.1 - 0.074 12.9 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 Matrixin Exo_endo_phos PF03372.23 ORY91674.1 - 6.5e-08 32.4 0.1 1.7e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SGL PF08450.12 ORY91675.1 - 6.8e-55 186.3 0.0 8.3e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORY91675.1 - 0.037 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 Arylesterase ACI44 PF15270.6 ORY91675.1 - 0.092 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-carboxypeptidase inhibitor zf-GRF PF06839.12 ORY91676.1 - 3.7e-10 39.7 5.3 6e-10 39.0 5.3 1.4 1 0 0 1 1 1 1 GRF zinc finger Pox_A3L PF05288.11 ORY91676.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Poxvirus A3L Protein TACC_C PF05010.14 ORY91676.1 - 0.19 11.5 5.1 0.45 10.3 5.1 1.5 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MARVEL PF01284.23 ORY91677.1 - 0.033 14.2 9.3 0.052 13.6 9.3 1.3 1 0 0 1 1 1 0 Membrane-associating domain Glyco_transf_8 PF01501.20 ORY91678.1 - 2.3e-25 89.6 0.0 2.3e-24 86.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 ORY91678.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase PCI PF01399.27 ORY91680.1 - 2.2e-22 79.5 0.7 5.3e-22 78.3 0.7 1.7 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 ORY91680.1 - 0.00049 19.9 0.2 1 9.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY91680.1 - 0.002 18.4 0.0 0.57 10.5 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY91680.1 - 0.0035 17.3 1.0 0.096 12.8 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY91680.1 - 0.0086 15.9 0.1 6.4 6.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY91680.1 - 0.043 13.7 0.1 0.37 10.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY91680.1 - 0.058 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 TPR repeat CSN8_PSD8_EIF3K PF10075.9 ORY91680.1 - 0.059 13.4 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family DprA_WH PF17782.1 ORY91680.1 - 0.13 12.4 0.2 0.68 10.1 0.0 2.1 1 1 1 2 2 2 0 DprA winged helix domain Keratin_2_head PF16208.5 ORY91680.1 - 3.4 7.8 22.6 5.4 7.1 22.6 1.2 1 0 0 1 1 1 0 Keratin type II head SKN1 PF03935.15 ORY91682.1 - 7.9e-152 506.2 0.4 9.3e-152 505.9 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Sugar_tr PF00083.24 ORY91683.1 - 5.5e-119 398.0 11.1 6.4e-119 397.8 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY91683.1 - 1.8e-14 53.4 32.3 8.3e-11 41.4 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY91684.1 - 1.9e-18 66.6 33.8 1.9e-18 66.6 33.8 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily PIRT PF15099.6 ORY91684.1 - 0.097 12.3 0.8 1.6 8.3 0.0 2.8 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family Q_salvage PF10343.9 ORY91685.1 - 2.4e-101 339.1 0.0 2.8e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family PCI PF01399.27 ORY91686.1 - 2.4e-19 69.8 0.0 1.3e-18 67.4 0.0 2.4 2 2 0 2 2 2 1 PCI domain RPN5_C PF18098.1 ORY91686.1 - 2.3e-15 56.4 0.3 6.4e-15 55.0 0.3 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Paf67 PF10255.9 ORY91686.1 - 0.029 13.4 0.1 0.2 10.6 0.0 2.2 3 0 0 3 3 3 0 RNA polymerase I-associated factor PAF67 DUF3445 PF11927.8 ORY91688.1 - 5.3e-69 232.3 0.0 6.3e-69 232.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) EutQ PF06249.12 ORY91690.1 - 1.9e-11 44.0 0.0 2.2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 ORY91690.1 - 0.0038 16.9 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ORY91690.1 - 0.035 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin domain DUF3445 PF11927.8 ORY91691.1 - 2.5e-58 197.4 0.0 3.6e-58 196.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SDA1 PF05285.12 ORY91692.1 - 1.4e-88 297.6 44.7 1.4e-88 297.6 44.7 2.5 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 ORY91692.1 - 3.5e-12 46.4 0.7 1.8e-05 25.0 0.3 2.8 2 0 0 2 2 2 2 NUC130/3NT domain Cwf_Cwc_15 PF04889.12 ORY91692.1 - 0.0059 16.4 1.0 0.0059 16.4 1.0 4.0 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein DIT1_PvcA PF05141.12 ORY91692.1 - 3.9 6.9 9.8 0.11 11.9 1.3 2.5 3 0 0 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein Fumble PF03630.14 ORY91693.1 - 1.5e-131 438.5 0.0 2.1e-131 438.1 0.0 1.2 1 0 0 1 1 1 1 Fumble MreB_Mbl PF06723.13 ORY91693.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 MreB/Mbl protein Chromate_transp PF02417.15 ORY91695.1 - 9.1e-60 201.3 29.6 5.9e-31 107.7 11.7 2.3 2 0 0 2 2 2 2 Chromate transporter Thg1C PF14413.6 ORY91696.1 - 7.9e-44 148.7 0.0 1.9e-43 147.5 0.0 1.6 1 1 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 ORY91696.1 - 2.8e-43 146.9 0.0 3.9e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Methyltransf_16 PF10294.9 ORY91697.1 - 2.2e-08 34.1 0.0 2.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase TMEM220 PF15071.6 ORY91699.1 - 0.058 14.2 0.6 0.14 12.9 0.2 1.9 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF4131 PF13567.6 ORY91700.1 - 0.04 13.6 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WTF PF03303.13 ORY91700.1 - 2 8.1 3.9 2.9 7.5 3.0 1.6 1 1 1 2 2 2 0 WTF protein ADH_zinc_N PF00107.26 ORY91701.1 - 4.2e-08 33.2 0.0 7.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY91701.1 - 7.7e-05 22.5 0.2 0.00064 19.6 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY91701.1 - 0.0017 19.4 0.0 0.0031 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 ORY91701.1 - 0.033 14.1 0.1 0.15 12.0 0.1 2.0 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Tim17 PF02466.19 ORY91702.1 - 0.0015 18.9 5.2 0.0021 18.4 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family tRNA-synt_2b PF00587.25 ORY91703.1 - 4.3e-25 88.7 0.0 6.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORY91703.1 - 7.3e-15 55.1 0.6 1.5e-14 54.2 0.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain FmiP_Thoc5 PF09766.9 ORY91703.1 - 0.049 12.9 0.5 0.074 12.3 0.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 tRNA-synt_2d PF01409.20 ORY91703.1 - 0.053 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) MAD PF05557.13 ORY91703.1 - 0.26 9.6 1.1 0.37 9.1 1.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Enkurin PF13864.6 ORY91703.1 - 0.41 11.1 2.0 1.5 9.3 0.9 2.1 2 0 0 2 2 2 0 Calmodulin-binding TPR_MLP1_2 PF07926.12 ORY91703.1 - 2.5 8.2 6.6 0.31 11.1 2.1 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 ORY91703.1 - 2.6 8.5 4.7 9.5 6.7 0.0 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 ORY91703.1 - 2.9 7.2 6.1 0.31 10.3 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GST_N_3 PF13417.6 ORY91704.1 - 3.9e-13 49.6 0.0 7.3e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY91704.1 - 2e-08 34.5 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY91704.1 - 1.9e-07 31.3 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY91704.1 - 1.6e-06 28.0 0.1 3.1e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY91704.1 - 0.00032 21.2 0.0 0.00056 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY91704.1 - 0.11 12.7 0.1 0.9 9.8 0.0 2.4 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SF3A2 PF16835.5 ORY91706.1 - 4.7e-39 132.6 0.0 8.7e-39 131.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 ORY91706.1 - 1.8e-06 28.1 2.7 2e-06 28.0 0.7 2.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 ORY91706.1 - 0.00017 21.5 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein MFS_2 PF13347.6 ORY91707.1 - 5.3e-08 31.8 4.0 5.3e-08 31.8 4.0 2.9 3 1 0 3 3 3 1 MFS/sugar transport protein BT1 PF03092.16 ORY91707.1 - 0.04 12.1 1.6 0.065 11.5 1.6 1.2 1 0 0 1 1 1 0 BT1 family DUF3708 PF12501.8 ORY91708.1 - 0.088 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter SET PF00856.28 ORY91709.1 - 1.5e-10 41.7 0.0 8.2e-10 39.3 0.0 2.0 1 1 0 1 1 1 1 SET domain PGC7_Stella PF15549.6 ORY91709.1 - 0.034 14.1 0.7 0.056 13.4 0.7 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain VEGF_C PF14554.6 ORY91709.1 - 0.081 13.0 1.2 0.17 12.0 1.2 1.4 1 0 0 1 1 1 0 VEGF heparin-binding domain AAA_33 PF13671.6 ORY91709.1 - 0.16 12.1 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain PQ-loop PF04193.14 ORY91710.1 - 1.2e-07 31.4 0.4 9.9e-06 25.2 0.2 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF2048 PF09752.9 ORY91712.1 - 0.16 11.0 0.3 0.26 10.3 0.3 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Ribosomal_L17 PF01196.19 ORY91713.1 - 1.9e-29 102.4 0.0 4e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 HHH_8 PF14716.6 ORY91713.1 - 0.11 12.8 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain TraA PF05513.11 ORY91714.1 - 0.0074 16.6 0.2 0.013 15.9 0.2 1.3 1 0 0 1 1 1 1 TraA Tetraspanin PF00335.20 ORY91714.1 - 0.0088 15.8 17.6 0.048 13.4 17.6 1.9 1 1 0 1 1 1 1 Tetraspanin family Cation_ATPase_C PF00689.21 ORY91714.1 - 0.25 11.0 14.5 1.2 8.8 0.7 2.1 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus TMEM171 PF15471.6 ORY91714.1 - 0.36 9.8 4.0 0.16 10.9 1.9 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 HR_lesion PF05514.11 ORY91714.1 - 0.49 10.6 0.0 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 HR-like lesion-inducing Jagunal PF07086.12 ORY91714.1 - 0.7 9.9 6.9 0.54 10.3 3.0 2.1 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis DUF2417 PF10329.9 ORY91714.1 - 2.1 7.7 6.7 3.3 7.0 6.7 1.3 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF308 PF03729.13 ORY91714.1 - 4 7.8 24.7 17 5.8 17.8 3.1 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) RTA1 PF04479.13 ORY91715.1 - 5.5e-24 84.9 7.8 5.5e-24 84.9 7.8 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3169 PF11368.8 ORY91715.1 - 0.08 12.4 2.7 0.26 10.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) DNA_pol_E_B PF04042.16 ORY91716.1 - 3.7e-31 108.1 0.0 5.5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 ORY91716.1 - 8.1e-23 81.7 0.1 1.1e-22 81.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal AlaDh_PNT_N PF05222.15 ORY91717.1 - 6.3e-29 101.0 0.0 8.8e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 ORY91717.1 - 0.051 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ras PF00071.22 ORY91718.1 - 3.8e-54 182.7 0.0 4.3e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY91718.1 - 7.9e-22 77.7 0.0 1.1e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY91718.1 - 5.4e-07 29.2 0.0 7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY91718.1 - 0.0049 16.4 0.0 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY91718.1 - 0.076 12.9 0.0 0.91 9.4 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Cupin_8 PF13621.6 ORY91719.1 - 1.4e-64 218.3 0.0 1.6e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORY91719.1 - 0.00047 19.7 0.0 0.00082 18.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein SDA1 PF05285.12 ORY91720.1 - 0.044 13.2 3.3 0.062 12.7 3.3 1.3 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 ORY91720.1 - 0.094 12.0 3.0 0.13 11.6 3.0 1.2 1 0 0 1 1 1 0 BUD22 Astro_capsid_p PF12226.8 ORY91720.1 - 2 7.5 20.4 3 6.9 20.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Hydrolase_4 PF12146.8 ORY91721.1 - 6.3e-06 25.6 0.0 0.00031 20.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY91721.1 - 0.004 16.8 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Aldose_epim PF01263.20 ORY91722.1 - 7.1e-19 68.2 0.0 1.4e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 Aldose 1-epimerase AdoMet_MTase PF07757.13 ORY91723.1 - 1.7e-31 108.8 0.1 3.4e-30 104.7 0.1 2.2 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 ORY91723.1 - 0.012 15.6 0.0 0.51 10.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORY91723.1 - 0.27 11.0 0.3 0.56 10.0 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase domain Phosphodiest PF01663.22 ORY91724.1 - 4.4e-11 43.0 0.5 2e-09 37.5 0.5 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY91724.1 - 1.5e-05 24.6 0.0 7.1e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Sulfatase DsbD PF02683.15 ORY91724.1 - 0.0027 17.6 1.4 0.0027 17.6 1.4 2.1 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Metalloenzyme PF01676.18 ORY91724.1 - 0.0083 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily TENA_THI-4 PF03070.16 ORY91724.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family GTP_EFTU PF00009.27 ORY91725.1 - 1.1e-64 217.5 0.2 1.6e-64 217.0 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY91725.1 - 1.7e-28 98.9 0.0 5.1e-28 97.3 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY91725.1 - 2.6e-22 78.6 0.0 6.1e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ORY91725.1 - 3.8e-13 49.3 0.0 8.3e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ORY91725.1 - 6e-12 45.8 0.0 2.4e-11 43.9 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY91725.1 - 1.2e-05 25.3 0.2 2.7e-05 24.2 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TAF4 PF05236.14 ORY91727.1 - 1.7e-21 77.2 5.3 1.2e-20 74.5 5.3 2.3 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Radial_spoke_3 PF06098.11 ORY91727.1 - 0.65 9.2 6.4 29 3.8 6.7 2.3 2 0 0 2 2 2 0 Radial spoke protein 3 GST_N_3 PF13417.6 ORY91728.1 - 6.5e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY91728.1 - 3.2e-11 43.4 0.0 5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY91728.1 - 2.6e-10 40.4 0.0 4.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY91728.1 - 4.9e-06 26.5 0.0 9.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY91728.1 - 0.0039 17.8 0.0 0.0066 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 ORY91728.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_N_4 PF17172.4 ORY91728.1 - 0.068 13.9 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain DUF4592 PF15262.6 ORY91729.1 - 0.35 11.6 18.8 0.52 11.0 18.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Tmemb_cc2 PF10267.9 ORY91729.1 - 5.8 6.0 8.1 6.5 5.8 8.1 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PhoD PF09423.10 ORY91730.1 - 4.8e-108 361.3 2.8 5.8e-108 361.0 2.8 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ORY91730.1 - 1.9e-19 70.0 0.0 4.1e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ORY91730.1 - 6.2e-06 26.7 0.0 2.1e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Peptidase_M24 PF00557.24 ORY91732.1 - 4.2e-51 173.6 0.0 5.6e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY91732.1 - 1.8e-14 53.5 0.0 4.6e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF2433 PF10360.9 ORY91733.1 - 4.3e-41 139.9 0.0 6.7e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 ORY91733.1 - 0.03 14.5 0.0 0.098 12.8 0.1 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain LRR_8 PF13855.6 ORY91734.1 - 1e-07 31.6 5.1 1e-07 31.6 5.1 2.7 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY91734.1 - 1.8e-05 25.0 12.9 5.3e-05 23.5 3.5 3.5 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY91734.1 - 0.042 14.4 6.0 8.5 7.4 0.7 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat DIRP PF06584.13 ORY91734.1 - 0.065 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 DIRP LRR_6 PF13516.6 ORY91734.1 - 0.62 10.3 7.4 77 3.7 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich repeat DUF4592 PF15262.6 ORY91735.1 - 0.045 14.4 20.0 0.059 14.0 20.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Apt1 PF10351.9 ORY91735.1 - 1.9 7.2 14.3 2.1 7.1 14.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 ORY91735.1 - 3.8 5.8 7.4 4.4 5.5 7.4 1.0 1 0 0 1 1 1 0 Menin Tmemb_cc2 PF10267.9 ORY91735.1 - 3.9 6.5 7.5 4.5 6.3 7.5 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Hid1 PF12722.7 ORY91735.1 - 3.9 5.5 6.5 4.3 5.3 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein QWRF PF04484.12 ORY91735.1 - 6.7 6.4 17.7 7.7 6.2 17.7 1.1 1 0 0 1 1 1 0 QWRF family DUF1190 PF06693.11 ORY91735.1 - 8.7 6.7 14.9 0.93 9.9 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1190) UPF0020 PF01170.18 ORY91736.1 - 8.4e-09 35.4 0.0 1.6e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 ORY91736.1 - 3.5e-06 26.9 0.0 0.089 12.5 0.0 2.6 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.16 ORY91736.1 - 0.00068 19.0 0.0 0.0023 17.3 0.0 1.7 1 1 0 1 1 1 1 N-6 DNA Methylase Cons_hypoth95 PF03602.15 ORY91736.1 - 0.04 13.5 0.0 0.086 12.5 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 DUF4123 PF13503.6 ORY91739.1 - 0.059 13.8 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) YscO PF07321.12 ORY91739.1 - 0.32 10.9 2.2 0.27 11.2 0.2 1.8 2 0 0 2 2 2 0 Type III secretion protein YscO DUF3248 PF11609.8 ORY91741.1 - 0.097 12.6 0.4 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) RNA_pol_Rpb1_1 PF04997.12 ORY91742.1 - 1.4e-84 284.1 0.0 2e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 ORY91742.1 - 1.6e-79 267.1 0.1 2.9e-79 266.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY91742.1 - 2.5e-70 236.0 0.0 5.3e-70 234.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY91742.1 - 6.6e-41 139.9 0.0 1.5e-40 138.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY91742.1 - 4.6e-32 110.2 0.0 1.2e-31 108.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF1178 PF06676.11 ORY91742.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Vfa1 PF08432.10 ORY91743.1 - 2.4e-31 109.5 0.4 4.6e-31 108.6 0.4 1.4 1 1 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DAZAP2 PF11029.8 ORY91743.1 - 0.00028 21.8 0.5 0.00053 20.9 0.5 1.4 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) DUF4718 PF15842.5 ORY91743.1 - 0.31 10.8 2.7 0.29 10.9 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4718) Mito_fiss_reg PF05308.11 ORY91743.1 - 1.7 8.7 9.2 3.2 7.8 0.2 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator Arrestin_N PF00339.29 ORY91745.1 - 1.1e-05 25.6 0.1 0.00013 22.0 0.1 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 ORY91747.1 - 4.1e-05 23.7 0.1 0.00098 19.2 0.0 2.4 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY91747.1 - 0.018 15.5 0.0 3.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Phage-tail_2 PF09096.10 ORY91747.1 - 0.22 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 VIT PF08487.10 ORY91748.1 - 2e-32 111.7 0.1 4.3e-32 110.6 0.1 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 ORY91748.1 - 7.6e-28 97.4 0.0 1.5e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 ORY91748.1 - 9.6e-15 55.3 0.0 3.9e-14 53.3 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY91748.1 - 2e-10 41.3 0.1 6.3e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 ORY91748.1 - 0.0018 18.1 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 ORY91748.1 - 0.003 17.0 0.2 0.0076 15.7 0.1 1.6 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein CobT_C PF11775.8 ORY91748.1 - 0.052 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Glyco_hydro_16 PF00722.21 ORY91749.1 - 1.1e-05 24.9 0.9 1.9e-05 24.2 0.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 ORY91750.1 - 0.00015 21.3 0.1 0.0022 17.5 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Gram_pos_anchor PF00746.21 ORY91750.1 - 0.2 11.6 0.3 0.4 10.7 0.3 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Glyco_trans_2_3 PF13632.6 ORY91751.1 - 6e-45 153.6 3.9 6e-45 153.6 3.9 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY91751.1 - 4.6e-06 26.7 0.0 1.4e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY91751.1 - 7.8e-06 25.8 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY91751.1 - 0.0086 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 CagE_TrbE_VirB PF03135.14 ORY91751.1 - 0.035 14.2 0.1 0.059 13.5 0.1 1.2 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF1380 PF07128.12 ORY91751.1 - 0.49 10.6 1.9 2.4 8.4 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1380) adh_short_C2 PF13561.6 ORY91753.1 - 3e-52 177.5 1.7 3.6e-52 177.2 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY91753.1 - 5.3e-48 163.1 1.2 6.3e-48 162.8 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY91753.1 - 2.4e-08 34.1 1.6 4.5e-08 33.2 1.6 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY91753.1 - 0.002 17.6 0.1 0.0033 16.9 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY91753.1 - 0.0031 16.6 0.3 0.045 12.8 0.2 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY91753.1 - 0.13 11.6 0.1 0.17 11.2 0.1 1.4 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase DnaJ PF00226.31 ORY91754.1 - 1.1e-19 70.3 0.1 3.4e-19 68.7 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_19 PF14559.6 ORY91754.1 - 1.5e-17 63.8 12.8 0.012 16.1 0.1 7.4 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORY91754.1 - 5.4e-14 51.1 7.2 0.0028 17.7 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY91754.1 - 7.7e-13 48.4 5.0 0.0066 16.6 0.0 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY91754.1 - 1e-12 47.3 2.0 0.0014 18.3 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY91754.1 - 5.4e-10 38.7 1.6 0.0082 16.3 0.0 4.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY91754.1 - 2.9e-08 33.5 6.9 0.0026 18.0 0.0 5.7 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY91754.1 - 9.8e-08 32.2 25.3 0.015 16.0 0.0 8.6 3 2 7 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY91754.1 - 8.9e-06 26.0 10.7 4.5 8.1 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY91754.1 - 2.3e-05 24.1 6.4 1.3 9.3 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY91754.1 - 0.00015 22.3 20.0 0.11 13.1 0.0 5.8 6 1 0 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY91754.1 - 0.00017 21.8 4.8 1.7 8.9 0.0 4.5 2 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY91754.1 - 0.00017 21.8 12.1 2 8.8 0.2 6.8 5 2 2 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY91754.1 - 0.0013 18.7 0.3 0.024 14.7 0.0 3.2 3 0 0 3 3 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 ORY91754.1 - 0.0015 18.2 0.9 0.38 10.5 0.0 4.5 4 1 1 5 5 5 1 TPR repeat TPR_20 PF14561.6 ORY91754.1 - 0.0028 18.0 6.4 0.74 10.2 0.1 3.7 3 1 2 5 5 4 2 Tetratricopeptide repeat RTX PF02382.15 ORY91754.1 - 0.0049 16.6 0.0 3.5 7.2 0.2 2.3 2 0 0 2 2 2 2 N-terminal domain in RTX protein GST_C_2 PF13410.6 ORY91754.1 - 0.014 15.4 0.0 0.088 12.9 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain YfiO PF13525.6 ORY91754.1 - 0.019 14.7 0.0 0.28 10.9 0.2 2.6 3 0 0 3 3 3 0 Outer membrane lipoprotein Coatomer_E PF04733.14 ORY91754.1 - 0.066 12.6 0.4 0.59 9.5 0.1 2.4 2 1 0 2 2 2 0 Coatomer epsilon subunit DUF410 PF04190.13 ORY91754.1 - 0.093 12.5 0.4 0.18 11.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF410) ANAPC5 PF12862.7 ORY91754.1 - 0.14 12.2 1.0 3.2 7.9 0.1 3.2 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 ORY91754.1 - 0.25 10.7 9.0 3.4 7.0 1.0 3.7 4 1 0 4 4 4 0 MalT-like TPR region CAP_N PF01213.19 ORY91754.1 - 0.35 10.3 3.1 0.15 11.5 0.4 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Spectrin PF00435.21 ORY91754.1 - 0.45 11.0 4.8 16 6.0 0.0 3.4 3 0 0 3 3 3 0 Spectrin repeat TPR_4 PF07721.14 ORY91754.1 - 0.76 10.6 0.1 0.76 10.6 0.1 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat MIF4G_like PF09088.11 ORY91755.1 - 6.2e-64 215.3 0.0 1.2e-63 214.4 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 ORY91755.1 - 1.2e-59 202.0 0.0 1.2e-58 198.8 0.1 2.0 2 0 0 2 2 2 1 MIF4G like PPR_2 PF13041.6 ORY91756.1 - 5e-10 39.4 0.0 5.5e-08 32.9 0.0 3.3 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.6 ORY91756.1 - 1.7e-07 31.2 0.0 2.3e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 ORY91756.1 - 0.06 13.6 0.0 11 6.5 0.0 3.7 3 0 0 3 3 3 0 PPR repeat Clathrin PF00637.20 ORY91756.1 - 0.25 11.2 0.0 0.48 10.3 0.0 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS Macoilin PF09726.9 ORY91757.1 - 0.82 8.2 6.0 0.91 8.0 6.0 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 ORY91757.1 - 5.8 5.6 10.4 6.7 5.5 10.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4551 PF15087.6 ORY91757.1 - 8.6 5.1 8.9 14 4.4 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP-alpha_N PF04086.13 ORY91757.1 - 8.8 6.2 17.9 12 5.7 17.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LIM_bind PF01803.16 ORY91758.1 - 3e-40 138.3 0.0 1.6e-39 135.9 0.0 2.1 2 0 0 2 2 2 1 LIM-domain binding protein WW PF00397.26 ORY91759.1 - 1.7e-07 31.2 0.8 3.1e-07 30.4 0.8 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 ORY91759.1 - 0.00047 20.3 28.8 0.00047 20.3 28.8 2.3 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) TFIID-31kDa PF02291.15 ORY91760.1 - 3.9e-36 123.8 0.0 4.8e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIID_30kDa PF03540.13 ORY91760.1 - 0.044 13.7 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 ORY91760.1 - 0.092 12.8 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Bromodomain associated MSP1_C PF07462.11 ORY91760.1 - 0.35 9.5 0.6 0.5 9.0 0.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus NOA36 PF06524.12 ORY91760.1 - 7.2 5.8 7.3 11 5.2 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein zf-MYND PF01753.18 ORY91761.1 - 5.1e-10 39.3 7.1 7.9e-10 38.7 7.1 1.3 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.18 ORY91762.1 - 3e-10 40.0 7.3 4.5e-10 39.4 7.3 1.3 1 0 0 1 1 1 1 MYND finger RRM_1 PF00076.22 ORY91763.1 - 1.7e-38 130.2 0.0 7.6e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY91763.1 - 2.1e-06 27.7 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY91763.1 - 0.11 12.5 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Glyco_hydro_18 PF00704.28 ORY91764.1 - 4.1e-58 197.6 2.5 4.1e-58 197.6 2.5 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 Lipase_GDSL_2 PF13472.6 ORY91764.1 - 0.033 14.6 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family GHL6 PF14871.6 ORY91764.1 - 0.14 12.3 0.0 0.97 9.6 0.0 2.1 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF349 PF03993.12 ORY91764.1 - 1.8 8.9 3.6 6.8 7.1 1.6 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Arrestin_N PF00339.29 ORY91766.1 - 0.00018 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Mito_carr PF00153.27 ORY91767.1 - 2.1e-50 168.6 5.8 3.9e-17 61.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Arf PF00025.21 ORY91768.1 - 1.7e-62 209.9 0.1 2e-62 209.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORY91768.1 - 4.6e-13 49.0 0.2 3.8e-08 32.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 ORY91768.1 - 5.3e-13 49.2 0.0 8.4e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY91768.1 - 9.6e-11 41.5 0.0 1.1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY91768.1 - 3.4e-09 36.5 0.0 4.4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 ORY91768.1 - 1.1e-08 35.2 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY91768.1 - 3.2e-08 33.2 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 ORY91768.1 - 0.0022 17.6 0.0 0.088 12.3 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORY91768.1 - 0.0052 16.3 0.1 0.013 15.1 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B PPK2 PF03976.14 ORY91768.1 - 0.016 14.7 0.1 0.54 9.7 0.0 2.1 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) HBS1_N PF08938.10 ORY91768.1 - 0.97 9.8 2.4 5.3 7.4 1.0 2.5 1 1 1 2 2 2 0 HBS1 N-terminus zf-MYND PF01753.18 ORY91769.1 - 9.5e-10 38.4 8.1 1.9e-09 37.5 8.1 1.5 1 0 0 1 1 1 1 MYND finger SlyX PF04102.12 ORY91769.1 - 0.029 15.0 0.0 0.056 14.1 0.0 1.4 1 0 0 1 1 1 0 SlyX DUF3150 PF11348.8 ORY91769.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Cpn60_TCP1 PF00118.24 ORY91771.1 - 4.4e-143 477.5 13.8 5e-143 477.3 13.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 ORY91771.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Peptidase_C12 PF01088.21 ORY91772.1 - 5.3e-57 193.0 0.0 6.1e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 zf-MYND PF01753.18 ORY91773.1 - 4.6e-08 33.0 10.4 4.6e-08 33.0 10.4 1.7 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 ORY91773.1 - 0.039 13.8 5.9 0.039 13.8 5.9 2.2 2 0 0 2 2 2 0 HIT zinc finger Prok-RING_2 PF14445.6 ORY91773.1 - 0.073 13.3 1.2 0.16 12.2 1.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-MYND PF01753.18 ORY91774.1 - 2.1e-05 24.5 8.2 2.1e-05 24.5 8.2 2.1 2 0 0 2 2 2 1 MYND finger AKAP95 PF04988.12 ORY91774.1 - 0.052 13.8 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-MYND PF01753.18 ORY91775.1 - 1.3e-09 38.0 6.3 2.4e-09 37.1 6.3 1.5 1 0 0 1 1 1 1 MYND finger SH3_9 PF14604.6 ORY91776.1 - 2.1e-10 40.3 0.0 4.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY91776.1 - 1.8e-06 27.4 0.0 4.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY91776.1 - 0.00044 19.9 0.0 0.00074 19.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Glyco_transf_21 PF13506.6 ORY91777.1 - 0.013 15.0 0.0 0.055 12.9 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY91777.1 - 0.18 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 UNC45-central PF11701.8 ORY91778.1 - 7e-17 61.8 0.0 1.6e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central HEAT PF02985.22 ORY91778.1 - 0.0065 16.6 11.9 0.35 11.3 0.1 4.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 ORY91778.1 - 0.0076 16.6 12.2 0.1 13.0 0.8 5.0 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 ORY91778.1 - 0.037 14.5 7.4 0.57 10.8 0.1 5.1 5 0 0 5 5 5 0 HEAT-like repeat Arm PF00514.23 ORY91778.1 - 3.1 8.0 13.8 0.8 9.8 0.3 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Pox_Ag35 PF03286.14 ORY91780.1 - 1.5 8.6 29.1 1 9.1 17.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Macoilin PF09726.9 ORY91780.1 - 8.9 4.7 13.2 9.8 4.6 13.2 1.2 1 0 0 1 1 1 0 Macoilin family GDPD_2 PF13653.6 ORY91781.1 - 0.0045 17.4 2.9 0.5 10.9 0.5 2.7 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 ORY91781.1 - 0.011 15.4 0.0 0.71 9.6 0.0 2.6 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 ORY91784.1 - 0.014 15.8 3.9 0.85 10.2 1.1 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family N2227 PF07942.12 ORY91785.1 - 1.3e-77 260.6 0.0 1.8e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 ORY91785.1 - 0.00077 20.1 0.0 0.014 16.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY91785.1 - 0.0026 18.4 0.0 0.27 11.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY91785.1 - 0.019 14.8 0.0 0.77 9.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORY91785.1 - 0.087 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MIP PF00230.20 ORY91786.1 - 6.9e-44 150.2 7.2 8.7e-44 149.9 7.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein Lys_export PF03956.13 ORY91786.1 - 0.00029 20.4 4.9 0.032 13.8 2.1 2.2 2 0 0 2 2 2 2 Lysine exporter LysO DUF5337 PF17272.2 ORY91786.1 - 0.13 12.1 1.6 5.4 6.9 0.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Glyco_hydro_65m PF03632.15 ORY91787.1 - 2.4e-32 112.3 1.5 1.7e-28 99.6 0.4 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 ORY91787.1 - 2.6e-21 76.3 0.0 5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.25 ORY91787.1 - 3.3e-07 30.5 0.0 1.3e-06 28.5 0.0 2.1 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_65C PF03633.15 ORY91787.1 - 0.00013 21.8 0.0 0.003 17.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain DUF2152 PF10222.9 ORY91787.1 - 0.17 10.2 0.0 0.3 9.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Cellulase PF00150.18 ORY91788.1 - 7.2e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.7 ORY91789.1 - 0.048 13.6 0.1 0.17 11.8 0.1 2.1 1 0 0 1 1 1 0 F-box-like TIP49 PF06068.13 ORY91790.1 - 7.8e-162 538.4 0.1 1.5e-161 537.5 0.1 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY91790.1 - 2e-22 79.1 0.0 5.3e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORY91790.1 - 2.3e-11 44.2 0.2 1.8e-07 31.6 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY91790.1 - 3.8e-09 36.5 0.0 4e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY91790.1 - 2e-06 28.1 0.2 0.042 14.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY91790.1 - 3.1e-05 24.4 0.8 0.00069 20.0 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 ORY91790.1 - 0.0001 22.7 0.6 0.074 13.4 0.0 2.4 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY91790.1 - 0.00036 20.6 0.2 0.15 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORY91790.1 - 0.00061 20.1 0.1 0.0019 18.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 ORY91790.1 - 0.0022 17.4 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 ORY91790.1 - 0.0059 16.3 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 ORY91790.1 - 0.0092 15.4 0.1 0.4 10.0 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORY91790.1 - 0.011 15.3 0.0 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY91790.1 - 0.014 14.6 0.1 0.032 13.5 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 ORY91790.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 ORY91790.1 - 0.03 13.6 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 ORY91790.1 - 0.076 12.7 0.2 2 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY91790.1 - 0.083 12.2 0.2 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 ORY91790.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 ORY91790.1 - 0.097 13.1 0.2 0.35 11.3 0.0 2.0 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 ORY91790.1 - 0.11 12.5 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY91790.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 ORY91790.1 - 0.17 11.9 0.1 5.3 7.0 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit GDI PF00996.18 ORY91791.1 - 5.4e-36 124.1 0.0 1.8e-35 122.3 0.0 1.6 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 ORY91791.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-MYND PF01753.18 ORY91792.1 - 0.00015 21.8 2.2 0.00021 21.3 2.2 1.3 1 0 0 1 1 1 1 MYND finger Snf7 PF03357.21 ORY91793.1 - 2.7e-49 167.1 10.4 3.1e-49 166.9 10.4 1.0 1 0 0 1 1 1 1 Snf7 Prefoldin_2 PF01920.20 ORY91793.1 - 0.021 14.8 9.2 0.15 12.0 0.0 3.3 2 1 2 4 4 4 0 Prefoldin subunit DUF1319 PF07028.11 ORY91793.1 - 0.026 14.8 2.5 0.036 14.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Prefoldin PF02996.17 ORY91793.1 - 0.028 14.3 10.9 0.15 12.0 0.1 3.3 2 1 1 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 ORY91793.1 - 0.034 14.6 6.6 0.13 12.7 0.1 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.11 ORY91793.1 - 0.085 12.4 3.7 1.1 8.7 0.1 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein FlxA PF14282.6 ORY91793.1 - 0.18 11.8 11.6 0.087 12.8 7.6 2.2 1 1 1 2 2 2 0 FlxA-like protein TRPM_tetra PF16519.5 ORY91793.1 - 0.18 11.9 4.8 0.24 11.5 1.8 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM APG6_N PF17675.1 ORY91793.1 - 0.2 12.2 0.2 0.2 12.2 0.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 ORY91793.1 - 0.68 7.8 7.5 0.85 7.5 7.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 ORY91793.1 - 0.86 9.7 8.7 4.4 7.4 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) XhlA PF10779.9 ORY91793.1 - 1.1 9.5 6.2 4 7.7 0.2 2.9 2 1 1 3 3 3 0 Haemolysin XhlA FapA PF03961.13 ORY91793.1 - 1.6 7.2 9.5 0.57 8.7 2.0 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A CorA PF01544.18 ORY91793.1 - 1.7 7.9 4.9 3.9 6.7 4.9 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein RPW8 PF05659.11 ORY91793.1 - 2.2 8.0 8.3 0.46 10.2 3.9 2.1 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Csm2_III-A PF03750.13 ORY91793.1 - 2.3 9.1 7.4 9 7.2 1.7 2.3 1 1 1 2 2 2 0 Csm2 Type III-A Uso1_p115_C PF04871.13 ORY91793.1 - 3.3 8.1 13.7 6.6 7.1 11.3 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region ABC_tran_CTD PF16326.5 ORY91793.1 - 5.3 7.4 11.9 3.9 7.8 0.1 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 ORY91793.1 - 7.7 6.7 10.4 17 5.6 6.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.24 ORY91793.1 - 8.3 6.3 8.4 3.8 7.4 0.2 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3292 PF11696.8 ORY91795.1 - 2.8e-89 300.3 0.0 2.2e-88 297.3 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) MSP PF01716.18 ORY91796.1 - 0.077 12.2 0.0 0.087 12.0 0.0 1.0 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Cyclin_N PF00134.23 ORY91797.1 - 1.9e-13 50.3 0.5 1.2e-12 47.7 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY91797.1 - 0.00047 20.2 1.7 0.00047 20.2 1.7 2.0 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORY91797.1 - 0.088 12.9 3.4 0.15 12.2 0.1 2.4 2 1 1 3 3 3 0 Cyclin, C-terminal domain MSP PF01716.18 ORY91798.1 - 0.077 12.2 0.0 0.087 12.0 0.0 1.0 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Cyclin_N PF00134.23 ORY91801.1 - 2.4e-13 50.0 0.5 1.4e-12 47.4 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY91801.1 - 0.00053 20.0 1.7 0.00053 20.0 1.7 2.0 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORY91801.1 - 0.091 12.9 3.1 0.17 12.0 0.1 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain SpoIISA_toxin PF14171.6 ORY91802.1 - 0.38 10.4 0.7 0.54 9.9 0.7 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF3328 PF11807.8 ORY91803.1 - 0.087 12.6 0.4 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) CBFD_NFYB_HMF PF00808.23 ORY91804.1 - 1.3e-16 60.6 1.1 1.8e-16 60.1 0.4 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY91804.1 - 9.6e-13 48.6 0.6 9.6e-13 48.6 0.6 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 IPK PF03770.16 ORY91804.1 - 0.074 12.9 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase Pns11_12 PF17464.2 ORY91804.1 - 0.18 11.5 1.2 0.3 10.8 1.2 1.3 1 0 0 1 1 1 0 Non-structural protein 11 and 12 CENP-X PF09415.10 ORY91804.1 - 0.21 11.9 0.4 1.8 8.9 0.1 2.2 1 1 1 2 2 2 0 CENP-S associating Centromere protein X G_path_suppress PF15991.5 ORY91804.1 - 0.43 10.7 4.6 0.91 9.6 0.1 2.1 1 1 1 2 2 2 0 G-protein pathway suppressor Trypan_PARP PF05887.11 ORY91804.1 - 1.1 9.3 14.0 1.8 8.5 14.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PNP_UDP_1 PF01048.20 ORY91805.1 - 3.4e-39 134.5 0.0 4.2e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 ORY91806.1 - 7.2e-24 84.3 0.1 2.1e-23 82.8 0.1 1.6 1 1 1 2 2 2 1 Phosphorylase superfamily zf-RING_11 PF17123.5 ORY92389.1 - 1.1e-09 37.9 11.1 2e-09 37.0 11.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY92389.1 - 1.6e-06 28.3 15.2 1.6e-06 28.3 15.2 1.6 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 ORY92389.1 - 0.0027 17.7 5.6 0.0053 16.8 5.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY92389.1 - 0.067 13.5 11.1 0.079 13.3 9.5 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY92389.1 - 0.1 12.5 15.7 0.19 11.6 15.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY92389.1 - 0.32 10.6 9.8 0.61 9.7 9.8 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 ORY92389.1 - 0.34 10.8 15.7 0.74 9.7 15.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY92389.1 - 0.44 10.6 13.8 0.83 9.7 13.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Furin-like_2 PF15913.5 ORY92390.1 - 9.1e-27 93.3 166.6 9.1e-06 25.8 16.4 11.7 2 2 10 12 12 12 12 Furin-like repeat, cysteine-rich Furin-like PF00757.20 ORY92390.1 - 2.6e-08 33.9 201.7 0.014 15.2 25.1 9.8 2 2 7 9 9 9 8 Furin-like cysteine rich region tRNA_bind PF01588.20 ORY92391.1 - 1.7e-28 98.5 0.1 4e-28 97.4 0.1 1.7 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 ORY92391.1 - 3.2e-05 24.0 0.1 0.00016 21.9 0.0 2.2 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY92391.1 - 7e-05 23.0 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY92391.1 - 0.087 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain KdgT PF03812.13 ORY92391.1 - 0.69 9.2 2.9 1.2 8.3 2.9 1.3 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease Ribosomal_L28e PF01778.17 ORY92392.1 - 9.5e-40 135.9 0.3 9.5e-40 135.9 0.3 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 ORY92392.1 - 2.2e-26 92.4 19.3 2.2e-26 92.4 19.3 2.3 2 0 0 2 2 2 1 Mak16 protein C-terminal region PYC_OADA PF02436.18 ORY92392.1 - 0.24 11.1 1.7 0.41 10.4 1.3 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain PI3K_1B_p101 PF10486.9 ORY92392.1 - 0.61 7.8 6.7 0.75 7.5 6.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sterol_MT_C PF08498.10 ORY92393.1 - 6.6e-30 103.2 0.3 1.1e-29 102.6 0.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 ORY92393.1 - 2.1e-19 69.8 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY92393.1 - 5.1e-19 68.7 0.0 8.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY92393.1 - 4.4e-17 62.6 0.0 7.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY92393.1 - 4.2e-14 52.7 0.0 6.7e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY92393.1 - 8.8e-13 48.9 0.0 2.1e-12 47.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 ORY92393.1 - 6.9e-12 45.2 0.0 9.9e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 ORY92393.1 - 3.9e-08 32.9 0.0 6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 ORY92393.1 - 0.0017 18.0 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase HRM PF02793.22 ORY92393.1 - 0.0024 18.1 1.4 0.0071 16.6 1.4 1.7 1 0 0 1 1 1 1 Hormone receptor domain PCMT PF01135.19 ORY92393.1 - 0.0046 16.7 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORY92393.1 - 0.0053 16.3 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 ORY92393.1 - 0.0096 16.9 0.0 0.022 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ORY92393.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 ORY92393.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain DUF5087 PF17006.5 ORY92393.1 - 0.049 13.2 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) Methyltransf_3 PF01596.17 ORY92393.1 - 0.081 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.18 ORY92393.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.20 ORY92394.1 - 2.6e-17 62.8 0.0 8.4e-17 61.1 0.0 1.7 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Peptidase_C13 PF01650.18 ORY92395.1 - 3e-46 158.0 0.1 3.6e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family RelB PF04221.12 ORY92395.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 RelB antitoxin ArgoMid PF16487.5 ORY92395.1 - 0.17 12.1 0.0 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute HCNGP PF07818.13 ORY92396.1 - 3.3e-24 85.3 0.0 7.6e-24 84.2 0.0 1.6 2 0 0 2 2 2 1 HCNGP-like protein UCH_1 PF13423.6 ORY92397.1 - 0.18 11.4 0.9 0.26 10.8 0.9 1.2 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Furin-like_2 PF15913.5 ORY92398.1 - 1.1e-25 89.9 188.8 3.7e-07 30.3 8.2 12.8 4 2 9 14 14 14 11 Furin-like repeat, cysteine-rich Endonuclease_5 PF04493.14 ORY92399.1 - 3.7e-48 163.9 0.0 7.8e-48 162.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease V DUF99 PF01949.16 ORY92399.1 - 0.054 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 Guanylate_kin PF00625.21 ORY92400.1 - 6.4e-59 198.7 0.0 7.3e-59 198.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 ORY92400.1 - 2.3e-05 24.8 0.0 9.2e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY92400.1 - 2.5e-05 24.6 0.0 0.00014 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY92400.1 - 0.00014 22.0 0.0 0.00077 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY92400.1 - 0.00077 19.8 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 ORY92400.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 ORY92400.1 - 0.001 19.6 0.0 0.0022 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY92400.1 - 0.0024 18.4 0.0 0.0033 17.9 0.0 1.3 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 ORY92400.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 ORY92400.1 - 0.008 16.4 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY92400.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ORY92400.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 ORY92400.1 - 0.016 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 ORY92400.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 ORY92400.1 - 0.021 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORY92400.1 - 0.035 14.5 0.0 0.066 13.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORY92400.1 - 0.05 12.8 0.0 0.33 10.1 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 ORY92400.1 - 0.06 13.3 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 ORY92400.1 - 0.062 13.2 0.1 0.13 12.2 0.0 1.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ORY92400.1 - 0.074 13.5 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY92400.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 ORY92400.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Septin Roc PF08477.13 ORY92400.1 - 0.1 12.8 0.1 0.25 11.6 0.0 1.7 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_21 PF13304.6 ORY92400.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Pox_A32 PF04665.12 ORY92400.1 - 0.24 10.8 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Adeno_IVa2 PF02456.15 ORY92400.1 - 0.26 10.1 0.0 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Nop25 PF09805.9 ORY92401.1 - 6.7 7.2 6.5 0.56 10.7 1.3 1.7 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ribosomal_L21p PF00829.21 ORY92402.1 - 5.6e-15 55.4 0.0 3.7e-08 33.6 0.1 2.1 2 0 0 2 2 2 2 Ribosomal prokaryotic L21 protein COesterase PF00135.28 ORY92403.1 - 4.7e-94 316.1 0.0 6.8e-94 315.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY92403.1 - 1.3e-08 35.0 0.0 4.4e-08 33.2 0.0 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY92403.1 - 0.035 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ribosomal_L10 PF00466.20 ORY92404.1 - 1.3e-24 86.2 1.0 5.7e-24 84.2 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 ORY92404.1 - 2.9e-20 72.0 0.0 5.3e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 ORY92404.1 - 4.7e-20 72.0 8.7 4.7e-20 72.0 8.7 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein VEG PF06257.11 ORY92404.1 - 0.045 13.8 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Biofilm formation stimulator VEG Plus-3 PF03126.18 ORY92405.1 - 2.2e-29 102.2 0.0 4.7e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain Furin-like_2 PF15913.5 ORY92410.1 - 4e-10 39.8 79.3 0.00055 20.1 16.1 6.4 1 1 5 6 6 6 6 Furin-like repeat, cysteine-rich Furin-like PF00757.20 ORY92410.1 - 3e-05 23.9 103.5 0.045 13.6 27.9 5.7 1 1 5 6 6 6 5 Furin-like cysteine rich region zf-RING_2 PF13639.6 ORY92411.1 - 7.2e-13 48.7 5.5 9.5e-13 48.3 5.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY92411.1 - 2e-10 40.8 6.9 6.1e-10 39.2 6.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY92411.1 - 5.6e-10 38.9 3.6 9.1e-10 38.2 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY92411.1 - 1.1e-09 37.8 2.0 1.1e-09 37.8 2.0 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY92411.1 - 4.7e-09 36.0 2.8 6.7e-09 35.5 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY92411.1 - 3.3e-08 33.4 2.3 4.6e-08 32.9 2.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY92411.1 - 1.6e-07 31.2 1.7 2.5e-07 30.6 1.7 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY92411.1 - 8.9e-07 28.9 2.2 1.1e-06 28.6 2.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY92411.1 - 2.8e-05 23.7 5.8 4.2e-05 23.1 5.8 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 ORY92411.1 - 0.00025 20.9 7.8 0.00034 20.4 7.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 ORY92411.1 - 0.0054 16.6 2.2 0.0054 16.6 2.2 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.8 ORY92411.1 - 0.0075 16.4 6.1 0.018 15.2 6.1 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING-like PF08746.11 ORY92411.1 - 0.047 14.0 9.5 0.42 11.0 9.5 2.0 1 1 0 1 1 1 0 RING-like domain zf-Nse PF11789.8 ORY92411.1 - 0.074 12.9 3.4 0.12 12.2 3.4 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 ORY92411.1 - 0.083 13.0 6.0 0.17 12.1 5.3 1.8 1 1 0 1 1 1 0 RING-variant domain ATG11 PF10377.9 ORY92411.1 - 0.24 11.5 0.0 0.24 11.4 0.0 1.1 1 0 0 1 1 1 0 Autophagy-related protein 11 zf-C3H2C3 PF17122.5 ORY92411.1 - 0.29 11.2 9.2 0.86 9.7 6.1 2.7 1 1 1 2 2 2 0 Zinc-finger BUD22 PF09073.10 ORY92412.1 - 0.059 12.7 12.9 0.1 12.0 12.9 1.3 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.25 ORY92413.1 - 1.4e-70 237.7 0.0 2e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92413.1 - 6.9e-40 137.0 0.0 1.1e-39 136.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 ORY92413.1 - 3.8e-31 107.1 3.0 4e-16 59.0 0.5 2.5 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 ORY92413.1 - 5.7e-07 29.1 0.0 3.6e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY92413.1 - 0.043 12.6 1.0 0.094 11.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 ORY92413.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY92413.1 - 0.086 12.2 0.1 6.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY92413.1 - 0.18 10.7 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Peptidase_C50 PF03568.17 ORY92414.1 - 3.1e-130 434.9 0.0 1e-129 433.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase family C50 RsbRD_N PF14361.6 ORY92414.1 - 0.15 12.7 2.4 53 4.6 0.0 4.4 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain SPA PF08616.10 ORY92415.1 - 5.3e-37 126.3 0.0 9.5e-37 125.4 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 ORY92415.1 - 3.8e-22 79.2 0.0 2.3e-21 76.7 0.0 2.2 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 ORY92415.1 - 8.8e-09 34.5 0.0 0.0012 17.6 0.0 2.9 2 1 1 3 3 3 2 Transport protein Avl9 DUF2347 PF09804.9 ORY92415.1 - 0.00044 19.9 0.0 0.68 9.5 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) Prefoldin_3 PF13758.6 ORY92415.1 - 0.055 13.5 0.3 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Prefoldin subunit Furin-like_2 PF15913.5 ORY92417.1 - 1.1e-15 57.7 114.1 0.00019 21.5 13.2 8.2 1 1 7 9 9 9 8 Furin-like repeat, cysteine-rich Furin-like PF00757.20 ORY92417.1 - 0.00011 22.1 143.4 0.24 11.3 20.1 7.7 1 1 5 6 6 6 6 Furin-like cysteine rich region CBF PF03914.17 ORY92419.1 - 4.9e-33 114.6 0.9 1.9e-32 112.6 0.0 2.5 3 1 0 3 3 3 1 CBF/Mak21 family PHA_synth_III_E PF09712.10 ORY92419.1 - 0.085 11.9 0.1 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) HAT PF02184.16 ORY92420.1 - 2.6e-21 75.2 62.7 5.9e-09 35.7 0.2 15.7 15 2 0 15 15 15 5 HAT (Half-A-TPR) repeat Suf PF05843.14 ORY92420.1 - 7.7e-14 52.4 17.0 8.5e-05 22.7 0.2 6.2 3 2 3 7 7 7 5 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY92420.1 - 2.3e-11 43.5 33.8 0.15 13.0 0.0 13.3 6 3 9 15 15 14 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY92420.1 - 5.8e-11 42.8 1.9 0.019 15.5 0.0 6.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY92420.1 - 1.5e-09 37.5 4.0 0.3 11.5 0.1 7.7 7 1 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY92420.1 - 8.5e-06 25.8 23.4 0.0062 16.5 3.1 6.7 4 2 1 6 6 6 3 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 ORY92420.1 - 0.00039 20.3 10.2 1.2 9.4 0.0 7.9 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY92420.1 - 0.0016 18.7 8.4 5.1 7.5 0.0 6.3 9 0 0 9 9 7 2 Tetratricopeptide repeat RAB3GAP2_C PF14656.6 ORY92420.1 - 0.0089 14.3 0.1 0.0089 14.3 0.1 1.4 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit C-terminus TPR_16 PF13432.6 ORY92420.1 - 0.019 15.6 25.5 0.078 13.6 0.1 7.9 9 1 2 11 11 10 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 ORY92420.1 - 0.63 10.1 19.1 1.7 8.8 0.2 6.4 6 1 1 7 7 7 0 U3 small nucleolar RNA-associated protein 6 Com_YlbF PF06133.11 ORY92421.1 - 0.071 13.7 1.4 0.16 12.6 1.4 1.5 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA LRR_8 PF13855.6 ORY92422.1 - 4.1 7.2 6.1 19 5.1 0.2 4.1 3 2 0 3 3 3 0 Leucine rich repeat Glyco_hydro_31 PF01055.26 ORY92423.1 - 2e-79 267.9 0.0 3.5e-79 267.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY92423.1 - 8.1e-14 51.7 1.0 2e-13 50.4 1.0 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1769 PF08588.10 ORY92424.1 - 4.1e-22 78.1 0.0 7.6e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) RRM_1 PF00076.22 ORY92425.1 - 4.4e-34 116.1 0.0 8.6e-17 60.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3932 PF13068.6 ORY92425.1 - 0.024 14.9 0.0 2.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) FNIP_M PF14637.6 ORY92425.1 - 0.16 11.9 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain SOG2 PF10428.9 ORY92425.1 - 3.7 6.6 9.3 7 5.7 9.3 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_S5 PF00333.20 ORY92426.1 - 7e-16 58.0 0.2 7e-16 58.0 0.2 3.0 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain WD40 PF00400.32 ORY92426.1 - 7.1e-16 58.3 24.4 0.0026 18.6 0.0 10.4 11 0 0 11 11 11 5 WD domain, G-beta repeat Ribosomal_S5_C PF03719.15 ORY92426.1 - 8.6e-14 50.8 0.0 2.3e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain ANAPC4_WD40 PF12894.7 ORY92426.1 - 1.5e-12 47.6 0.1 0.0095 16.2 0.0 6.1 2 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY92426.1 - 0.00055 19.0 2.3 0.42 9.5 0.1 3.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY92426.1 - 0.01 14.5 1.5 0.048 12.3 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 BBS2_N PF14781.6 ORY92426.1 - 0.022 14.7 0.0 0.67 9.9 0.0 3.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal PQQ PF01011.21 ORY92426.1 - 0.49 10.4 1.7 4.2 7.5 0.1 3.2 3 0 0 3 3 3 0 PQQ enzyme repeat Symplekin_C PF12295.8 ORY92427.1 - 2.8e-57 193.8 3.6 2.9e-57 193.8 1.4 2.2 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 ORY92427.1 - 3.1e-46 157.8 0.0 8.9e-46 156.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) V-ATPase_G PF03179.15 ORY92428.1 - 1.2e-32 112.6 10.9 1.3e-32 112.4 10.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Mis12 PF05859.12 ORY92428.1 - 0.0091 16.1 1.0 0.02 15.0 1.0 1.6 1 1 0 1 1 1 1 Mis12 protein RE_MjaI PF09568.10 ORY92428.1 - 0.03 14.2 0.3 0.038 13.8 0.3 1.2 1 0 0 1 1 1 0 MjaI restriction endonuclease Apolipoprotein PF01442.18 ORY92428.1 - 0.039 13.8 7.0 0.049 13.5 7.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TPR_21 PF09976.9 ORY92428.1 - 0.05 13.3 3.8 0.058 13.1 3.8 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain FANCI_S2 PF14676.6 ORY92428.1 - 0.053 13.8 0.7 0.093 13.0 0.7 1.5 1 1 0 1 1 1 0 FANCI solenoid 2 DUF4407 PF14362.6 ORY92428.1 - 0.086 12.2 4.8 0.099 12.0 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.18 ORY92428.1 - 0.13 12.3 15.9 0.037 14.1 8.9 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) CdiI_2 PF18593.1 ORY92428.1 - 0.27 11.9 2.1 0.82 10.4 0.4 2.0 1 1 1 2 2 2 0 CdiI immunity protein V-ATPase_G_2 PF16999.5 ORY92428.1 - 0.3 11.5 10.3 0.51 10.8 10.3 1.3 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF4239 PF14023.6 ORY92428.1 - 0.3 10.8 1.8 0.38 10.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) KfrA_N PF11740.8 ORY92428.1 - 0.41 11.3 5.9 1.2 9.8 2.5 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term RRF PF01765.19 ORY92428.1 - 0.5 10.3 7.1 0.79 9.7 7.1 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF3072 PF11272.8 ORY92428.1 - 0.61 10.0 4.4 0.39 10.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) DUF1690 PF07956.11 ORY92428.1 - 0.85 10.0 7.8 1.1 9.7 7.8 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) NTF2 PF02136.20 ORY92429.1 - 4.6e-28 98.2 0.0 6.6e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ORY92429.1 - 1.7e-08 34.2 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 ORY92430.1 - 5.1e-13 48.7 0.0 6.8e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY92430.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec23_trunk PF04811.15 ORY92431.1 - 1.7e-58 198.0 0.0 2.6e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY92431.1 - 2.7e-26 91.4 0.2 5.4e-26 90.4 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY92431.1 - 4.5e-19 69.0 0.0 8.2e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY92431.1 - 5.2e-14 52.0 2.4 9.3e-14 51.2 2.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY92431.1 - 1.5e-05 24.8 0.0 6.4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat Syntaxin_2 PF14523.6 ORY92432.1 - 2.9e-26 91.8 9.0 4.7e-25 87.9 1.0 2.4 3 0 0 3 3 3 2 Syntaxin-like protein SNARE PF05739.19 ORY92432.1 - 1.4e-12 47.4 0.2 4.8e-12 45.7 0.2 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 ORY92432.1 - 6.6e-05 22.7 10.4 0.00065 19.4 10.0 2.4 1 1 1 2 2 2 1 Syntaxin DUF802 PF05650.11 ORY92432.1 - 0.029 14.8 2.2 0.029 14.8 2.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF802) SlyX PF04102.12 ORY92432.1 - 0.036 14.7 0.7 0.036 14.7 0.7 3.2 4 2 1 5 5 5 0 SlyX SPATIAL PF15256.6 ORY92432.1 - 0.038 14.3 1.4 0.052 13.9 0.9 1.3 1 1 0 1 1 1 0 SPATIAL DUF4988 PF16378.5 ORY92432.1 - 0.039 13.6 1.9 0.4 10.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function OmpH PF03938.14 ORY92432.1 - 0.43 10.9 14.8 1.6 9.0 10.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 ORY92432.1 - 1.3 9.3 6.9 0.81 10.0 1.0 2.9 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Prominin PF05478.11 ORY92432.1 - 1.3 6.8 4.6 3.1 5.6 4.6 1.7 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 ORY92432.1 - 3.3 7.8 7.5 1.1 9.3 1.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 ORY92432.1 - 6.3 6.8 17.8 0.2 11.8 10.5 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DNA_pol_A_exo1 PF01612.20 ORY92433.1 - 5.8e-10 39.2 0.0 1e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PIF2 PF04631.12 ORY92433.1 - 0.095 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Per os infectivity factor 2 Methyltransf_23 PF13489.6 ORY92436.1 - 5e-10 39.5 0.0 8.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY92436.1 - 9e-10 39.1 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY92436.1 - 1.1e-09 38.9 0.0 1.7e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY92436.1 - 3.6e-06 27.6 0.0 5.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY92436.1 - 7.1e-05 22.2 0.0 9.9e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 ORY92436.1 - 0.00045 20.0 0.0 0.00085 19.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY92436.1 - 0.0063 15.8 0.0 0.0083 15.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain MetW PF07021.12 ORY92436.1 - 0.084 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 ORY92436.1 - 0.12 13.4 0.3 0.24 12.4 0.3 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 ORY92436.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BRE1 PF08647.11 ORY92437.1 - 0.049 13.7 10.7 0.062 13.4 1.4 3.7 1 1 3 4 4 4 0 BRE1 E3 ubiquitin ligase HALZ PF02183.18 ORY92437.1 - 0.2 11.9 2.6 1.8 8.8 0.1 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper HAUS6_N PF14661.6 ORY92437.1 - 0.52 9.9 10.3 8.7 5.8 0.0 3.1 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus Lebercilin PF15619.6 ORY92437.1 - 1.2 8.8 17.0 0.17 11.5 7.5 3.1 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 ORY92437.1 - 2.3 7.0 17.3 1.5 7.7 5.3 3.2 2 1 2 4 4 4 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 ORY92437.1 - 2.5 8.2 25.2 2.4 8.3 2.8 3.9 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 ORY92437.1 - 5 7.2 5.0 2.3 8.3 0.6 2.6 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 ORY92437.1 - 5.7 7.2 6.5 8.2 6.7 0.5 3.4 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Snapin_Pallidin PF14712.6 ORY92437.1 - 6.3 7.3 7.7 8.7 6.8 0.1 3.4 3 1 1 4 4 4 0 Snapin/Pallidin Filament PF00038.21 ORY92437.1 - 7.1 6.1 17.5 1.7 8.1 6.6 3.2 3 1 1 4 4 4 0 Intermediate filament protein CDP-OH_P_transf PF01066.21 ORY92438.1 - 2e-13 50.9 0.3 2e-13 50.9 0.3 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DAP3 PF10236.9 ORY92439.1 - 3.7e-54 184.0 0.0 4.5e-54 183.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 ORY92439.1 - 1.3e-08 35.4 0.2 2.2e-08 34.7 0.2 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 ORY92439.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY92439.1 - 0.0031 17.8 0.1 0.015 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY92439.1 - 0.0033 17.2 0.1 0.0068 16.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY92439.1 - 0.0037 17.0 0.1 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY92439.1 - 0.015 14.9 0.3 0.092 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY92439.1 - 0.025 13.8 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 ORY92439.1 - 0.1 12.5 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 ORY92439.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 ORY92439.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ORY92439.1 - 0.13 12.7 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 ORY92439.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.7 ORY92439.1 - 0.21 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Tim17 PF02466.19 ORY92440.1 - 1.2e-12 48.2 1.2 2.6e-12 47.1 0.8 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Podoplanin PF05808.11 ORY92441.1 - 0.0082 16.3 1.2 0.072 13.2 0.0 2.2 2 0 0 2 2 2 1 Podoplanin DUF1180 PF06679.12 ORY92441.1 - 0.013 15.9 0.6 0.013 15.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Alpha_GJ PF03229.13 ORY92441.1 - 0.1 13.2 4.7 0.3 11.6 4.7 1.8 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF4366 PF14283.6 ORY92441.1 - 0.12 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Pex14_N PF04695.13 ORY92441.1 - 2.2 8.9 8.3 0.11 13.1 1.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LapA_dom PF06305.11 ORY92441.1 - 2.3 8.1 3.4 0.81 9.5 0.3 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain WD40 PF00400.32 ORY92442.1 - 3.7e-15 56.1 12.4 4.7e-05 24.1 0.5 6.3 6 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92442.1 - 9.4e-11 41.9 0.0 0.00051 20.3 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 ORY92442.1 - 0.012 14.4 0.5 1 8.1 0.1 2.7 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 ORY92442.1 - 0.058 13.3 0.1 0.75 9.6 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Bystin PF05291.11 ORY92443.1 - 9.7e-134 445.2 0.0 1.7e-133 444.4 0.0 1.3 1 0 0 1 1 1 1 Bystin RNA_pol_3_Rpc31 PF11705.8 ORY92443.1 - 0.56 10.4 19.8 0.95 9.7 19.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 ORY92443.1 - 3.7 6.8 12.4 5.1 6.3 12.4 1.1 1 0 0 1 1 1 0 BUD22 Glycos_transf_2 PF00535.26 ORY92444.1 - 1.3e-30 106.4 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY92444.1 - 3.3e-13 50.0 0.0 4.8e-13 49.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORY92444.1 - 8.5e-05 22.1 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY92444.1 - 8.6e-05 22.1 0.0 0.00018 21.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 BPL_N PF09825.9 ORY92445.1 - 1.1e-104 350.6 0.0 1.7e-104 349.9 0.0 1.3 1 1 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 ORY92445.1 - 8.1e-25 87.2 0.0 1.4e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 ORY92445.1 - 0.004 16.8 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain BPL_C PF02237.17 ORY92445.1 - 0.005 16.7 1.8 0.027 14.4 1.8 2.2 1 1 0 1 1 1 1 Biotin protein ligase C terminal domain Zn_clus PF00172.18 ORY92446.1 - 6.8e-06 26.1 9.6 1.3e-05 25.2 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY92446.1 - 0.0024 16.9 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain BTB PF00651.31 ORY92447.1 - 1.8e-16 60.4 0.0 6.3e-13 48.9 0.0 3.2 3 0 0 3 3 3 2 BTB/POZ domain CAP_GLY PF01302.25 ORY92447.1 - 4.4e-09 36.2 0.4 8.5e-08 32.1 0.0 2.8 3 0 0 3 3 3 1 CAP-Gly domain HD PF01966.22 ORY92448.1 - 1.9e-06 28.1 0.7 3.1e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 HD domain BCDHK_Adom3 PF10436.9 ORY92449.1 - 1.9e-68 229.4 0.0 2.6e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY92449.1 - 4.6e-13 49.6 0.0 1.7e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY92449.1 - 9.2e-05 22.3 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rhomboid PF01694.22 ORY92450.1 - 1.6e-19 70.4 7.2 1.6e-19 70.4 7.2 1.7 2 0 0 2 2 2 1 Rhomboid family AAA_12 PF13087.6 ORY92451.1 - 5.6e-45 153.4 0.0 8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY92451.1 - 1.6e-27 97.0 0.1 3.5e-13 49.9 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY92451.1 - 2.8e-13 50.0 0.0 7.9e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhyH PF05721.13 ORY92451.1 - 4.3e-08 33.7 0.1 2e-07 31.5 0.0 2.1 3 0 0 3 3 2 1 Phytanoyl-CoA dioxygenase (PhyH) AAA_19 PF13245.6 ORY92451.1 - 1.5e-07 31.8 0.0 9.8e-07 29.2 0.0 2.4 2 2 0 2 2 2 1 AAA domain zf-met PF12874.7 ORY92451.1 - 7.8e-07 29.3 0.2 2.1e-06 27.9 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY92451.1 - 4.2e-06 26.9 0.2 1.1e-05 25.6 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Viral_helicase1 PF01443.18 ORY92451.1 - 1.7e-05 24.6 0.0 0.27 10.9 0.0 3.3 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase zf-DBF PF07535.12 ORY92451.1 - 0.00067 19.7 3.5 0.14 12.3 0.2 2.6 2 0 0 2 2 2 2 DBF zinc finger AAA_22 PF13401.6 ORY92451.1 - 0.0027 18.0 0.0 0.0081 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY92451.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORY92451.1 - 0.029 14.8 0.0 0.083 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain zf-CCCH PF00642.24 ORY92451.1 - 0.038 13.9 0.1 0.071 13.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA PF00004.29 ORY92451.1 - 0.04 14.3 0.2 0.11 13.0 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 ORY92451.1 - 0.043 13.3 0.0 9.5 5.6 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain zf-U1 PF06220.12 ORY92451.1 - 0.063 13.1 0.4 0.13 12.1 0.4 1.5 1 0 0 1 1 1 0 U1 zinc finger PhoH PF02562.16 ORY92451.1 - 0.08 12.4 0.0 14 5.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 ORY92451.1 - 0.12 11.6 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Kelch_6 PF13964.6 ORY92452.1 - 1e-09 38.3 3.8 0.00087 19.5 0.0 4.8 4 1 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 ORY92452.1 - 2.9e-09 36.8 7.2 5.2e-05 23.2 0.0 3.8 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY92452.1 - 1e-07 31.8 0.1 0.004 17.1 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 ORY92452.1 - 1.1e-06 28.7 13.0 8.7e-06 25.9 0.1 5.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY92452.1 - 4.1e-06 26.5 0.1 0.022 14.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 ORY92452.1 - 5.7e-05 22.6 3.9 0.16 11.6 0.0 3.9 3 1 0 3 3 3 2 Kelch motif adh_short PF00106.25 ORY92453.1 - 5.2e-30 104.4 0.0 4.1e-26 91.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY92453.1 - 3.6e-19 69.3 0.0 2.2e-18 66.7 0.0 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY92453.1 - 2.2e-12 47.2 0.1 3.8e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY92453.1 - 0.018 14.5 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY92453.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_3 PF01494.19 ORY92453.1 - 0.11 11.7 0.3 0.18 11.1 0.3 1.4 1 1 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 ORY92453.1 - 0.13 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MMtag PF10159.9 ORY92454.1 - 7.1e-32 109.5 2.7 7.1e-32 109.5 2.7 3.3 2 1 0 2 2 2 1 Multiple myeloma tumor-associated LAP1C PF05609.12 ORY92454.1 - 2.5 7.1 11.6 2.8 6.9 11.6 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3292 PF11696.8 ORY92454.1 - 2.5 6.4 6.1 3.6 5.9 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) TPT PF03151.16 ORY92455.1 - 1.1e-54 185.8 8.4 1.5e-54 185.3 8.4 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY92455.1 - 3.2e-05 24.1 31.4 0.001 19.2 12.5 3.6 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 ORY92455.1 - 6.5e-05 22.3 13.3 0.0062 15.8 2.6 2.2 2 0 0 2 2 2 2 UAA transporter family zf-HC5HC2H_2 PF13832.6 ORY92456.1 - 8.1e-18 64.6 7.2 8.1e-18 64.6 7.2 3.8 3 1 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY92456.1 - 1.5e-15 57.2 4.9 1.5e-15 57.2 4.9 4.5 4 2 1 5 5 5 1 PHD-like zinc-binding domain GATA PF00320.27 ORY92456.1 - 2.2e-13 49.6 8.7 1.3e-11 43.9 1.1 2.9 2 0 0 2 2 2 2 GATA zinc finger BAH PF01426.18 ORY92456.1 - 3e-11 43.3 0.1 9.4e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 ORY92456.1 - 2.5e-10 40.1 21.9 2.3e-07 30.6 9.7 5.6 5 1 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 ORY92456.1 - 1.8e-08 33.8 4.8 1.8e-08 33.8 4.8 4.5 4 0 0 4 4 4 1 PHD-finger Myb_DNA-binding PF00249.31 ORY92456.1 - 0.0023 18.1 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ELM2 PF01448.24 ORY92456.1 - 0.027 15.2 2.3 0.16 12.8 0.0 3.3 3 0 0 3 3 3 0 ELM2 domain EamA PF00892.20 ORY92457.1 - 9.2e-09 35.6 40.5 1.3e-05 25.4 6.1 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 ORY92457.1 - 0.00095 18.8 0.9 0.00095 18.8 0.9 1.8 2 1 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 ORY92457.1 - 0.16 11.3 10.2 0.69 9.2 4.7 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Ribosomal_L16 PF00252.18 ORY92458.1 - 1.1e-46 158.1 0.0 1.4e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e F-box-like PF12937.7 ORY92459.1 - 7.1e-05 22.6 0.5 0.00014 21.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY92459.1 - 0.012 15.5 0.4 0.24 11.3 0.2 2.9 2 1 0 2 2 2 0 F-box domain Ribosomal_60s PF00428.19 ORY92460.1 - 1.3e-21 77.0 14.3 1.5e-21 76.8 14.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Furin-like PF00757.20 ORY92461.1 - 2.4e-06 27.5 25.4 0.00089 19.1 7.1 3.2 1 1 2 3 3 3 3 Furin-like cysteine rich region VSP PF03302.13 ORY92461.1 - 0.00011 21.2 32.5 0.085 11.7 18.8 3.1 1 1 2 3 3 3 3 Giardia variant-specific surface protein GF_recep_IV PF14843.6 ORY92461.1 - 0.00021 21.1 30.8 0.05 13.4 7.8 3.4 1 1 2 3 3 3 2 Growth factor receptor domain IV Furin-like_2 PF15913.5 ORY92461.1 - 0.00032 20.8 26.8 0.0014 18.8 13.3 3.0 1 1 3 4 4 4 4 Furin-like repeat, cysteine-rich Fer4 PF00037.27 ORY92461.1 - 0.26 11.2 13.9 0.86 9.5 0.3 4.7 5 0 0 5 5 5 0 4Fe-4S binding domain TNFR_c6 PF00020.18 ORY92461.1 - 0.38 11.2 36.4 2.6 8.5 5.8 5.4 4 2 0 4 4 4 0 TNFR/NGFR cysteine-rich region Fer4_6 PF12837.7 ORY92461.1 - 0.42 10.8 0.2 0.42 10.8 0.2 6.0 8 0 0 8 8 8 0 4Fe-4S binding domain Furin-like PF00757.20 ORY92462.1 - 0.00085 19.2 32.6 0.00088 19.2 7.3 3.9 1 1 2 3 3 3 2 Furin-like cysteine rich region Furin-like_2 PF15913.5 ORY92462.1 - 0.0019 18.4 13.6 0.0019 18.4 13.6 4.1 2 1 3 5 5 5 2 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 ORY92462.1 - 0.0078 16.0 37.8 0.013 15.3 8.8 4.0 1 1 3 4 4 4 3 Growth factor receptor domain IV BAGE PF08180.11 ORY92462.1 - 0.047 13.8 0.3 0.089 12.9 0.3 1.4 1 0 0 1 1 1 0 B melanoma antigen family Fer4_4 PF12800.7 ORY92462.1 - 0.77 10.4 21.7 3.9 8.2 0.9 6.0 5 0 0 5 5 5 0 4Fe-4S binding domain TNFR_c6 PF00020.18 ORY92462.1 - 2.2 8.8 34.1 1.2 9.5 5.0 5.5 4 2 0 4 4 4 0 TNFR/NGFR cysteine-rich region Fer4_6 PF12837.7 ORY92462.1 - 2.4 8.4 18.9 0.64 10.2 0.2 6.0 6 0 0 6 6 6 0 4Fe-4S binding domain Fer4 PF00037.27 ORY92462.1 - 3.5 7.6 16.1 1.2 9.0 0.3 4.7 5 0 0 5 5 5 0 4Fe-4S binding domain MSC PF09402.10 ORY92462.1 - 4.7 6.6 8.6 6.9 6.0 8.6 1.4 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain PCI PF01399.27 ORY92463.1 - 3.1e-21 75.9 0.2 4.9e-21 75.2 0.2 1.3 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 ORY92463.1 - 2.2e-12 46.5 0.0 3.6e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain RPN6_N PF18055.1 ORY92466.1 - 3.3e-41 140.3 5.9 3.7e-41 140.1 3.2 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain DUF3533 PF12051.8 ORY92466.1 - 0.18 10.7 0.3 0.23 10.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) RPN7 PF10602.9 ORY92467.1 - 4e-49 166.7 0.9 6.5e-49 166.0 0.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORY92467.1 - 1.2e-11 45.0 0.0 3.2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 ORY92467.1 - 0.00031 20.8 0.0 0.00058 19.9 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family T6SS_VasJ PF16989.5 ORY92467.1 - 0.012 15.2 0.2 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Furin-like_2 PF15913.5 ORY92468.1 - 0.00041 20.5 13.4 0.00041 20.5 13.4 3.4 1 1 2 3 3 3 2 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 ORY92468.1 - 0.00095 19.0 40.5 0.0032 17.3 11.6 4.0 2 1 2 4 4 4 3 Growth factor receptor domain IV Furin-like PF00757.20 ORY92468.1 - 0.0022 17.9 34.7 0.0088 15.9 13.2 3.8 1 1 2 3 3 3 2 Furin-like cysteine rich region Fer4_6 PF12837.7 ORY92468.1 - 0.53 10.5 0.1 0.53 10.5 0.1 6.7 8 0 0 8 8 8 0 4Fe-4S binding domain VSP PF03302.13 ORY92468.1 - 0.8 8.5 41.9 0.39 9.5 19.2 3.9 1 1 3 4 4 4 0 Giardia variant-specific surface protein Fer4 PF00037.27 ORY92468.1 - 1.3 8.9 17.4 0.93 9.4 0.2 5.5 6 0 0 6 6 6 0 4Fe-4S binding domain Fer4_4 PF12800.7 ORY92468.1 - 2.8 8.7 26.9 4.3 8.1 1.0 6.5 6 0 0 6 6 6 0 4Fe-4S binding domain Ribosomal_S19 PF00203.21 ORY92469.1 - 1.7e-31 108.0 0.1 2.2e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PsiA PF06952.11 ORY92469.1 - 0.092 12.0 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 PsiA protein Furin-like_2 PF15913.5 ORY92470.1 - 0.00018 21.6 13.8 0.00018 21.6 13.8 3.3 1 1 2 3 3 3 2 Furin-like repeat, cysteine-rich Furin-like PF00757.20 ORY92470.1 - 0.00039 20.3 10.0 0.00039 20.3 10.0 4.1 2 1 2 4 4 4 3 Furin-like cysteine rich region GF_recep_IV PF14843.6 ORY92470.1 - 0.0007 19.4 45.4 0.0026 17.5 11.6 4.3 1 1 3 4 4 4 3 Growth factor receptor domain IV TNFR_c6 PF00020.18 ORY92470.1 - 0.013 15.8 32.6 1 9.8 3.6 5.4 4 2 0 4 4 4 0 TNFR/NGFR cysteine-rich region BAGE PF08180.11 ORY92470.1 - 0.12 12.4 0.5 0.22 11.6 0.5 1.4 1 0 0 1 1 1 0 B melanoma antigen family Fer4_4 PF12800.7 ORY92470.1 - 0.24 12.0 26.5 3.9 8.2 0.9 7.0 6 0 0 6 6 6 0 4Fe-4S binding domain EMP24_GP25L PF01105.24 ORY92471.1 - 4.8e-47 160.2 0.0 5.8e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BST2 PF16716.5 ORY92471.1 - 0.13 12.9 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 WD40 PF00400.32 ORY92472.1 - 4.1e-39 131.9 18.2 7.7e-09 36.0 0.3 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92472.1 - 7.2e-17 61.5 0.0 0.005 17.1 0.0 5.9 4 1 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 ORY92472.1 - 1.6e-13 50.0 6.9 2.9e-13 49.1 6.9 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like WD40_like PF17005.5 ORY92472.1 - 2.3e-06 27.1 0.0 0.00097 18.6 0.0 2.4 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.11 ORY92472.1 - 8.4e-06 25.8 0.0 0.3 10.9 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY92472.1 - 0.0048 15.9 0.0 5.4 5.9 0.0 3.9 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 ORY92472.1 - 0.11 11.8 0.9 6.2 6.1 0.0 3.3 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal SnoaL_4 PF13577.6 ORY92475.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Vps5 PF09325.10 ORY92476.1 - 1.9e-42 145.5 5.5 2.7e-42 145.0 5.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORY92476.1 - 1.2e-18 67.1 0.0 3.9e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 PX domain Stress-antifung PF01657.17 ORY92476.1 - 0.034 14.8 0.0 0.097 13.3 0.0 1.8 1 0 0 1 1 1 0 Salt stress response/antifungal BAR_3_WASP_bdg PF10456.9 ORY92476.1 - 0.037 13.5 0.5 0.081 12.4 0.5 1.5 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein SOAR PF16533.5 ORY92476.1 - 0.18 11.8 5.4 0.13 12.3 3.3 1.9 2 0 0 2 2 2 0 STIM1 Orai1-activating region Phage_HK97_TLTM PF06120.11 ORY92476.1 - 0.64 9.2 4.7 0.95 8.6 4.0 1.6 1 1 0 1 1 1 0 Tail length tape measure protein GrpE PF01025.19 ORY92476.1 - 1.5 8.4 8.1 0.4 10.3 4.3 2.0 2 0 0 2 2 2 0 GrpE BAR PF03114.18 ORY92476.1 - 1.7 8.3 7.8 0.16 11.6 2.4 1.8 2 0 0 2 2 2 0 BAR domain UPF0242 PF06785.11 ORY92476.1 - 9.3 6.3 7.6 1.6e+02 2.3 7.6 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF745 PF05335.13 ORY92476.1 - 9.7 5.9 11.9 2 8.1 2.7 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF745) Ferritin_2 PF13668.6 ORY92477.1 - 4.1e-43 146.8 4.2 6e-43 146.3 4.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain Zn_clus PF00172.18 ORY92478.1 - 5e-09 36.1 3.4 7.5e-09 35.6 3.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY92479.1 - 1.2e-12 47.4 0.1 6e-12 45.2 0.0 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 ORY92480.1 - 1.7e-17 63.4 44.1 1.2e-15 57.3 14.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2370 PF10176.9 ORY92480.1 - 0.19 11.3 0.6 0.38 10.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Glyco_hydro_88 PF07470.13 ORY92481.1 - 3.1e-14 52.8 0.2 4.5e-14 52.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 ORY92481.1 - 5.5e-05 22.8 1.0 0.00012 21.8 1.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cyto_heme_lyase PF01265.17 ORY92483.1 - 2.2e-69 234.3 20.1 9.4e-57 192.8 14.0 3.2 1 1 0 2 2 2 2 Cytochrome c/c1 heme lyase Exostosin PF03016.15 ORY92483.1 - 0.048 12.9 0.1 7.3 5.7 0.0 2.1 2 0 0 2 2 2 0 Exostosin family PQ-loop PF04193.14 ORY92484.1 - 1.1e-17 63.5 0.0 2.9e-12 46.2 0.0 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 ORY92484.1 - 0.056 14.3 0.5 0.17 12.7 0.5 1.8 1 1 0 1 1 1 0 ER lumen protein retaining receptor MFS_1 PF07690.16 ORY92484.1 - 0.71 8.7 8.0 1.9 7.3 6.9 2.0 1 1 0 1 1 1 0 Major Facilitator Superfamily AA_permease PF00324.21 ORY92485.1 - 5.1e-103 345.2 25.1 6.1e-103 345.0 25.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY92485.1 - 1.1e-19 70.6 29.8 2.2e-19 69.6 29.9 1.3 1 1 0 1 1 1 1 Amino acid permease MMPL PF03176.15 ORY92485.1 - 0.052 12.5 0.1 0.052 12.5 0.1 1.8 2 0 0 2 2 2 0 MMPL family AA_permease PF00324.21 ORY92486.1 - 1.3e-96 324.1 29.4 1.7e-96 323.8 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY92486.1 - 1.1e-14 54.2 31.9 1.7e-14 53.5 31.6 1.4 1 1 0 1 1 1 1 Amino acid permease AAA_12 PF13087.6 ORY92487.1 - 5.6e-45 153.4 0.0 1e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY92487.1 - 2.3e-25 89.9 0.0 3.1e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY92487.1 - 7.5e-12 45.4 0.0 2.7e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY92487.1 - 4.5e-07 30.3 0.0 4.2e-06 27.2 0.0 2.5 2 2 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.8 ORY92487.1 - 0.00016 21.9 0.4 0.00036 20.7 0.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Viral_helicase1 PF01443.18 ORY92487.1 - 0.00041 20.2 0.0 0.18 11.5 0.0 3.2 2 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase zf-met PF12874.7 ORY92487.1 - 0.00042 20.6 0.3 0.00091 19.5 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type ResIII PF04851.15 ORY92487.1 - 0.003 17.6 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-DBF PF07535.12 ORY92487.1 - 0.0071 16.4 3.8 1.9 8.7 0.7 2.8 2 0 0 2 2 2 2 DBF zinc finger AAA_22 PF13401.6 ORY92487.1 - 0.0082 16.4 0.0 0.072 13.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ORY92487.1 - 0.021 15.2 0.1 0.071 13.5 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY92487.1 - 0.041 13.4 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ORY92487.1 - 0.044 13.2 0.0 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein ATP-synt_ab PF00006.25 ORY92488.1 - 1.2e-72 244.0 0.0 1.7e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY92488.1 - 5.5e-43 146.3 0.1 8.9e-43 145.6 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY92488.1 - 1.5e-06 28.6 3.4 0.0099 16.4 0.2 3.4 3 1 1 4 4 4 2 ATP synthase alpha/beta family, beta-barrel domain Epimerase PF01370.21 ORY92490.1 - 2.9e-11 43.3 0.0 2.5e-10 40.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY92490.1 - 1.1e-08 35.2 0.0 1.7e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY92490.1 - 2.4e-08 33.3 0.0 5.9e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY92490.1 - 2.1e-06 27.1 0.0 7.2e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 ORY92490.1 - 0.00017 21.3 0.2 0.0011 18.6 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 ORY92490.1 - 0.0018 17.7 0.7 0.0099 15.3 0.0 2.4 3 0 0 3 3 3 1 short chain dehydrogenase KR PF08659.10 ORY92490.1 - 0.009 15.9 0.0 0.1 12.5 0.0 2.2 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY92490.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DFP PF04127.15 ORY92490.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3HCDH_N PF02737.18 ORY92490.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NT-C2 PF10358.9 ORY92491.1 - 3.4e-16 59.3 0.0 7e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins LisH PF08513.11 ORY92492.1 - 0.044 13.7 0.1 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 LisH Ribonuc_P_40 PF08584.11 ORY92493.1 - 5.2e-37 127.7 0.0 8.1e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Glyco_transf_64 PF09258.10 ORY92494.1 - 1.6e-40 139.0 0.0 1.2e-39 136.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain Glyco_tranf_2_3 PF13641.6 ORY92494.1 - 3.4e-05 23.9 0.0 0.0001 22.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DnaJ_CXXCXGXG PF00684.19 ORY92495.1 - 0.002 18.5 2.8 0.014 15.7 0.7 2.3 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 ORY92495.1 - 1.1 9.3 9.3 5.8 7.0 0.3 3.2 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 ORY92495.1 - 1.3 9.3 6.6 0.17 12.1 0.9 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5351) PET117 PF15786.5 ORY92496.1 - 1.8e-23 82.6 0.3 2.1e-23 82.4 0.3 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Amnionless PF14828.6 ORY92497.1 - 0.0075 15.1 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Amnionless COX14 PF14880.6 ORY92497.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly DAP10 PF07213.11 ORY92497.1 - 0.15 12.1 0.6 0.33 11.0 0.6 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Pol_alpha_B_N PF08418.10 ORY92497.1 - 6.7 6.6 9.4 11 5.9 9.4 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal F-box-like PF12937.7 ORY92498.1 - 1e-05 25.3 3.7 1.4e-05 24.9 2.3 2.0 2 0 0 2 2 2 1 F-box-like DUF1752 PF08550.10 ORY92499.1 - 4.9e-12 45.5 2.6 8.6e-12 44.7 2.6 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) 3Beta_HSD PF01073.19 ORY92501.1 - 3.6e-13 49.2 0.0 5.8e-13 48.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY92501.1 - 1e-10 41.5 0.0 2.8e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY92501.1 - 2.3e-08 33.5 0.0 1.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORY92501.1 - 5.2e-08 33.0 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding AA_permease PF00324.21 ORY92501.1 - 1.3e-07 30.6 0.7 2e-07 30.0 0.7 1.1 1 0 0 1 1 1 1 Amino acid permease NmrA PF05368.13 ORY92501.1 - 1.1e-06 28.4 0.0 0.00094 18.8 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY92501.1 - 0.0062 16.0 0.0 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase DFP PF04127.15 ORY92501.1 - 0.035 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.25 ORY92501.1 - 0.083 12.3 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase Epimerase PF01370.21 ORY92502.1 - 9.1e-09 35.1 0.0 3.8e-08 33.1 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY92502.1 - 5.9e-07 29.3 0.0 4e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_4 PF07993.12 ORY92502.1 - 8.7e-06 25.1 0.0 0.00011 21.4 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 ORY92502.1 - 0.00064 18.8 0.0 0.0008 18.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family stn_TNFRSF12A PF12191.8 ORY92503.1 - 0.14 12.4 1.1 0.68 10.2 0.3 2.6 2 1 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PIRT PF15099.6 ORY92503.1 - 0.16 11.5 0.0 0.44 10.1 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Podoplanin PF05808.11 ORY92503.1 - 0.74 9.9 3.5 0.71 10.0 0.2 2.6 2 0 0 2 2 2 0 Podoplanin DnaJ PF00226.31 ORY92504.1 - 1.9e-20 72.7 0.1 1.2e-19 70.2 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain DUF2052 PF09747.9 ORY92504.1 - 0.052 13.7 10.5 0.28 11.3 6.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PHM7_cyt PF14703.6 ORY92504.1 - 6.9 6.9 11.7 0.13 12.5 4.0 2.0 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter MAM33 PF02330.16 ORY92505.1 - 1.1e-66 224.8 0.0 1.3e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Pkinase PF00069.25 ORY92506.1 - 1.4e-71 241.0 0.0 1.8e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92506.1 - 1.2e-39 136.2 0.0 1.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY92506.1 - 2.9e-05 23.5 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY92506.1 - 0.00095 19.1 0.1 0.013 15.5 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY92506.1 - 0.0054 15.7 0.0 0.0087 15.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY92506.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 ORY92506.1 - 0.042 13.4 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 ORY92506.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Inositol_P PF00459.25 ORY92507.1 - 6.8e-64 216.0 0.0 7.7e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Apolipoprotein PF01442.18 ORY92508.1 - 4.4e-06 26.7 5.3 2.4e-05 24.3 1.1 2.7 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 ORY92508.1 - 0.0087 16.1 6.1 0.036 14.1 0.7 3.0 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 ORY92508.1 - 0.035 14.2 8.5 0.07 13.2 1.1 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) SF-assemblin PF06705.11 ORY92508.1 - 0.052 12.9 0.3 0.14 11.5 0.3 1.6 1 1 0 1 1 1 0 SF-assemblin/beta giardin NRD1_2 PF01995.16 ORY92508.1 - 0.089 12.1 0.1 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 NrpR regulatory domains NRD1 and 2 DUF883 PF05957.13 ORY92508.1 - 0.23 12.1 6.5 4.7 7.9 0.2 3.3 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ATG_C PF09333.11 ORY92508.1 - 0.85 10.0 5.4 6.4 7.2 1.7 3.4 2 1 1 3 3 3 0 Autophagy-related protein C terminal domain MscS_porin PF12795.7 ORY92508.1 - 0.87 9.1 15.4 0.24 10.9 6.5 3.0 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain 3Beta_HSD PF01073.19 ORY92509.1 - 5.6e-14 51.8 0.0 9.1e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY92509.1 - 6.8e-12 45.4 0.0 3.4e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY92509.1 - 3.4e-10 39.5 0.0 2.2e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORY92509.1 - 2.1e-07 31.0 0.0 3.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY92509.1 - 2.5e-05 24.0 0.0 0.0063 16.1 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 ORY92509.1 - 0.0089 15.5 0.1 0.017 14.5 0.0 1.8 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase DFP PF04127.15 ORY92509.1 - 0.038 13.8 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AA_permease PF00324.21 ORY92510.1 - 2.7e-102 342.8 31.8 3.2e-102 342.6 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY92510.1 - 8.7e-20 70.9 39.5 1.4e-19 70.3 39.4 1.3 1 1 0 1 1 1 1 Amino acid permease DUF2970 PF11174.8 ORY92510.1 - 0.55 10.1 0.0 0.55 10.1 0.0 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2970) eIF3_subunit PF08597.10 ORY92511.1 - 0.4 10.5 3.1 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit MFS_1 PF07690.16 ORY92512.1 - 1.2e-10 40.8 48.4 1.6e-09 37.2 43.4 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY92512.1 - 3.6e-05 22.4 26.1 0.00013 20.5 26.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.32 ORY92513.1 - 4.9e-09 36.7 5.7 0.084 13.8 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.6 ORY92513.1 - 0.2 12.2 6.5 16 6.1 0.0 4.3 3 1 1 4 4 4 0 PQQ-like domain SH3_9 PF14604.6 ORY92514.1 - 3.8e-25 87.5 4.1 1.3e-12 47.4 0.2 3.0 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 ORY92514.1 - 1.7e-22 78.8 4.3 1.9e-11 43.4 0.1 3.0 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 ORY92514.1 - 2.9e-19 68.5 0.1 2.6e-08 33.4 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 ORY92514.1 - 4.7e-16 58.7 0.0 7.8e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein eIF3_subunit PF08597.10 ORY92514.1 - 0.69 9.8 8.4 0.21 11.5 1.5 2.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit zf-HC5HC2H_2 PF13832.6 ORY92515.1 - 8.5e-32 109.6 7.2 8.5e-32 109.6 7.2 2.6 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY92515.1 - 2.4e-26 91.8 3.1 2.4e-26 91.8 3.1 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain Bromodomain PF00439.25 ORY92515.1 - 1.3e-19 70.1 0.1 2.4e-19 69.2 0.1 1.5 1 0 0 1 1 1 1 Bromodomain EPL1 PF10513.9 ORY92515.1 - 1.8e-19 70.7 0.1 1.8e-19 70.7 0.1 4.3 4 1 0 5 5 5 1 Enhancer of polycomb-like PHD_2 PF13831.6 ORY92515.1 - 9.2e-15 53.9 3.0 9.2e-15 53.9 3.0 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 ORY92515.1 - 8.2e-10 38.4 22.1 1.7e-09 37.4 8.9 2.8 2 0 0 2 2 2 2 PHD-finger PWWP PF00855.17 ORY92515.1 - 7.6e-09 35.9 0.0 4.5e-08 33.4 0.0 2.4 1 0 0 1 1 1 1 PWWP domain zf-RING-like PF08746.11 ORY92515.1 - 5.7 7.3 23.4 0.11 12.8 7.8 2.6 2 0 0 2 2 2 0 RING-like domain MFS_1 PF07690.16 ORY92516.1 - 9.2e-28 97.2 21.9 1.4e-27 96.6 21.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY92516.1 - 0.063 13.0 6.0 0.032 13.9 3.4 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 DUF4500 PF14937.6 ORY92516.1 - 0.16 12.0 0.8 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) TauD PF02668.16 ORY92517.1 - 2.8e-56 191.3 0.2 3.4e-56 191.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aldo_ket_red PF00248.21 ORY92518.1 - 4.4e-41 141.0 0.0 6e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_10 PF04967.12 ORY92518.1 - 0.076 12.8 0.3 34 4.4 0.0 3.5 3 0 0 3 3 3 0 HTH DNA binding domain Ribosomal_L14e PF01929.17 ORY92519.1 - 5.8e-33 113.2 5.0 8.2e-33 112.7 5.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORY92519.1 - 0.00042 20.2 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 KOW motif BTB PF00651.31 ORY92520.1 - 9.5e-06 25.8 0.0 0.00018 21.7 0.0 2.6 3 0 0 3 3 3 1 BTB/POZ domain DUF2953 PF11167.8 ORY92520.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) FF PF01846.19 ORY92521.1 - 9.3e-32 109.0 6.5 3.1e-11 43.3 0.0 5.9 6 0 0 6 6 6 4 FF domain WW PF00397.26 ORY92521.1 - 0.0064 16.6 5.3 0.0064 16.6 5.3 3.5 3 1 0 3 3 3 2 WW domain THP2 PF09432.10 ORY92521.1 - 0.033 14.3 1.8 2.4 8.2 0.2 3.3 3 0 0 3 3 3 0 Tho complex subunit THP2 RhoGAP-FF1 PF16512.5 ORY92521.1 - 1.8 9.3 11.5 2.1 9.1 0.6 3.6 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain BORG_CEP PF14957.6 ORY92521.1 - 3.6 8.8 6.2 18 6.5 1.7 3.0 3 0 0 3 3 3 0 Cdc42 effector RCC1 PF00415.18 ORY92523.1 - 1e-13 51.6 1.2 0.0012 19.4 0.0 6.6 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S5 PF00333.20 ORY92523.1 - 0.023 14.7 0.3 10 6.2 0.1 2.6 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain RCC1_2 PF13540.6 ORY92523.1 - 0.08 12.8 16.8 1.1 9.1 2.5 5.6 6 0 0 6 6 6 0 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.22 ORY92525.1 - 3.6e-30 103.6 0.0 6.7e-19 67.5 0.0 4.2 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY92525.1 - 1.3e-11 44.5 0.3 1.3e-07 31.7 0.1 2.3 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 ORY92525.1 - 0.022 14.4 0.0 2.2 7.9 0.0 2.7 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY92525.1 - 0.22 11.6 0.2 1.3 9.1 0.0 2.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif YbjN PF10722.9 ORY92526.1 - 0.042 13.9 0.1 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator TMF_TATA_bd PF12325.8 ORY92526.1 - 3.2 8.0 8.9 5.6 7.2 0.2 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FliJ PF02050.16 ORY92526.1 - 7.5 6.8 14.0 0.087 13.0 0.8 4.1 4 1 0 4 4 4 0 Flagellar FliJ protein TLD PF07534.16 ORY92528.1 - 1.6e-29 102.9 0.0 2.4e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 TLD tRNA_anti-codon PF01336.25 ORY92529.1 - 0.0015 18.5 0.0 0.0054 16.7 0.0 2.0 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Stn1 PF10451.9 ORY92529.1 - 0.088 11.8 0.5 0.69 8.8 0.1 2.2 2 0 0 2 2 2 0 Telomere regulation protein Stn1 PseudoU_synth_1 PF01416.20 ORY92530.1 - 5e-08 33.4 0.0 1.3e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase F-box-like PF12937.7 ORY92531.1 - 0.0031 17.4 0.3 0.0082 16.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 ORY92532.1 - 9.3e-06 25.4 1.8 2.2e-05 24.3 1.8 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 ORY92532.1 - 0.28 11.0 2.0 20 5.1 0.1 3.4 3 0 0 3 3 3 0 Leucine rich repeat WLM PF08325.10 ORY92533.1 - 1.1e-30 107.1 0.0 1.7e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 WLM domain RRM_1 PF00076.22 ORY92534.1 - 5.3e-53 176.7 0.0 7.6e-17 60.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY92534.1 - 5.8e-05 23.1 0.0 3 7.9 0.0 3.3 3 0 0 3 3 3 3 RNA binding motif PknH_C PF14032.6 ORY92534.1 - 0.0045 16.9 0.1 3.1 7.6 0.0 3.1 3 0 0 3 3 3 1 PknH-like extracellular domain Limkain-b1 PF11608.8 ORY92534.1 - 0.0067 16.5 0.0 3.2 7.9 0.0 3.0 2 1 0 2 2 2 2 Limkain b1 DUF3343 PF11823.8 ORY92534.1 - 0.037 13.5 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) RRM_9 PF18444.1 ORY92534.1 - 0.16 11.8 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Keratin_2_head PF16208.5 ORY92534.1 - 1.9 8.6 59.6 1.6 8.8 31.8 2.5 2 0 0 2 2 2 0 Keratin type II head PPTA PF01239.22 ORY92535.1 - 1.7e-44 148.3 10.6 1.4e-09 37.4 0.3 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.6 ORY92535.1 - 0.0024 18.5 0.1 0.72 10.5 0.0 3.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY92535.1 - 0.0079 16.5 2.2 2.3 8.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY92535.1 - 0.019 15.8 0.6 32 5.7 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat SIS PF01380.22 ORY92537.1 - 2.1e-18 66.4 0.1 2.7e-18 66.1 0.1 1.1 1 0 0 1 1 1 1 SIS domain 2-Hacid_dh_C PF02826.19 ORY92540.1 - 2.4e-55 186.6 0.0 3.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY92540.1 - 6.4e-19 67.9 0.0 7.5e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY92540.1 - 4.1e-07 30.3 0.1 7.2e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORY92540.1 - 3.4e-05 23.5 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 ORY92540.1 - 0.0035 17.9 0.0 0.0075 16.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.21 ORY92540.1 - 0.0053 16.8 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 ORY92540.1 - 0.057 13.1 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 ORY92540.1 - 0.075 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain DUF1996 PF09362.10 ORY92542.1 - 1.6e-56 191.9 0.2 2e-56 191.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF2156 PF09924.9 ORY92543.1 - 2.2e-16 59.7 0.0 2.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Abhydrolase_3 PF07859.13 ORY92544.1 - 1.4e-25 90.5 0.0 1.8e-25 90.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY92544.1 - 5.5e-06 25.5 0.0 1.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ORY92544.1 - 0.0079 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY92544.1 - 0.084 12.7 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FAT PF02259.23 ORY92545.1 - 4.3e-127 424.1 0.8 6.7e-127 423.5 0.2 1.6 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORY92545.1 - 7.6e-68 229.0 0.2 1.3e-67 228.3 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 ORY92545.1 - 7e-61 204.8 0.9 9.2e-54 181.7 0.0 6.4 5 2 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 ORY92545.1 - 6.7e-45 151.5 0.1 3e-44 149.5 0.1 2.3 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 ORY92545.1 - 5.7e-16 58.0 1.5 1e-15 57.2 0.5 2.1 2 0 0 2 2 2 1 FATC domain HEAT_2 PF13646.6 ORY92545.1 - 9.4e-16 58.0 18.3 0.031 14.7 0.0 9.7 5 2 3 8 8 8 4 HEAT repeats HEAT PF02985.22 ORY92545.1 - 8.2e-15 53.7 13.8 0.23 11.8 0.0 10.3 10 0 0 10 10 9 4 HEAT repeat TPR_19 PF14559.6 ORY92545.1 - 1.5e-07 31.8 0.6 0.17 12.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.7 ORY92545.1 - 1.3e-05 25.7 0.1 37 5.0 0.0 6.5 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY92545.1 - 0.0035 17.4 1.6 4.4 7.3 0.1 5.0 4 1 2 6 6 5 1 non-SMC mitotic condensation complex subunit 1 ANAPC3 PF12895.7 ORY92545.1 - 0.012 15.8 1.1 1.7 8.9 0.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3437 PF11919.8 ORY92545.1 - 0.015 15.2 0.0 7.5 6.6 0.0 4.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Adaptin_N PF01602.20 ORY92545.1 - 0.022 13.3 6.0 0.2 10.2 0.4 3.9 4 0 0 4 4 4 0 Adaptin N terminal region ParcG PF10274.9 ORY92545.1 - 0.086 13.0 0.2 3.9 7.5 0.0 3.6 3 0 0 3 3 3 0 Parkin co-regulated protein TPR_6 PF13174.6 ORY92545.1 - 0.099 13.3 1.5 31 5.5 0.1 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat HEAT_EZ PF13513.6 ORY92545.1 - 0.16 12.5 35.7 0.34 11.5 1.3 11.5 11 3 3 14 14 12 0 HEAT-like repeat TPR_2 PF07719.17 ORY92545.1 - 1.2 9.4 6.8 10 6.6 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY92545.1 - 3.5 8.4 9.4 1.3 9.8 0.6 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat MMS19_C PF12460.8 ORY92545.1 - 10 5.1 11.7 1.7 7.7 0.2 4.1 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal MFS_1 PF07690.16 ORY92546.1 - 1.1e-26 93.6 55.1 2.5e-20 72.7 21.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 ORY92548.1 - 2e-55 186.9 0.0 2.7e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY92548.1 - 1.2e-18 67.0 0.0 1.4e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY92548.1 - 9.7e-07 29.1 0.1 1.6e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 ORY92548.1 - 4.4e-05 23.1 0.0 7.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 ORY92548.1 - 0.0075 16.4 0.0 0.3 11.2 0.0 2.3 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.17 ORY92548.1 - 0.01 16.4 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 ORY92548.1 - 0.054 13.1 0.1 0.083 12.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 ORY92548.1 - 0.075 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain F-box-like PF12937.7 ORY92549.1 - 6e-07 29.3 0.7 1.5e-06 28.0 0.7 1.7 1 0 0 1 1 1 1 F-box-like SIS PF01380.22 ORY92550.1 - 3.3e-62 208.1 0.8 6.8e-32 110.1 0.1 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORY92550.1 - 7.5e-16 58.5 0.0 2.2e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY92550.1 - 4.8e-12 45.9 0.0 1.1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY92550.1 - 0.00013 21.0 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Zip PF02535.22 ORY92551.1 - 2e-24 86.4 5.0 4.1e-24 85.4 5.0 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DNA_pol_A_exo1 PF01612.20 ORY92552.1 - 4.4e-39 134.0 0.0 6.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 ORY92552.1 - 1.4e-13 51.4 0.0 6.8e-13 49.1 0.0 2.3 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 ORY92552.1 - 2e-10 40.5 0.4 4.4e-10 39.4 0.4 1.7 1 0 0 1 1 1 1 HRDC domain PRP21_like_P PF12230.8 ORY92552.1 - 0.62 9.9 3.2 1.5 8.6 3.2 1.6 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Nup35_RRM PF05172.13 ORY92553.1 - 4.6e-16 58.6 0.0 8.4e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 ORY92553.1 - 2.1e-05 24.4 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif F-box-like PF12937.7 ORY92554.1 - 2.6e-06 27.2 1.0 5.7e-06 26.1 1.0 1.6 1 0 0 1 1 1 1 F-box-like Adenylsucc_synt PF00709.21 ORY92555.1 - 2.3e-176 586.8 0.0 2.6e-176 586.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase POR PF01558.18 ORY92557.1 - 0.012 15.7 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Epimerase PF01370.21 ORY92558.1 - 5.1e-06 26.1 0.0 1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY92558.1 - 1.9e-05 23.8 0.0 3e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY92558.1 - 9.9e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY92558.1 - 0.00015 21.3 0.0 0.026 14.0 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase NAD_binding_10 PF13460.6 ORY92558.1 - 0.0033 17.3 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY92558.1 - 0.0036 16.5 0.0 0.005 16.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 ORY92558.1 - 0.017 14.7 0.0 0.068 12.7 0.1 1.9 2 1 0 2 2 2 0 NmrA-like family Amidase PF01425.21 ORY92559.1 - 1.7e-94 317.4 0.0 2e-94 317.1 0.0 1.0 1 0 0 1 1 1 1 Amidase WD40 PF00400.32 ORY92560.1 - 6.3e-13 49.0 2.9 0.12 13.2 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92560.1 - 0.013 15.8 0.2 43 4.5 0.0 4.4 5 1 1 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain CAAX_1 PF15895.5 ORY92561.1 - 0.11 12.4 4.7 0.069 13.1 2.0 1.8 2 0 0 2 2 2 0 CAAX box cerebral protein 1 Herpes_pp85 PF04637.12 ORY92561.1 - 0.17 10.3 2.7 0.22 9.9 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) GDP_Man_Dehyd PF16363.5 ORY92562.1 - 0.00018 21.0 0.0 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY92562.1 - 0.00019 21.0 0.1 0.00066 19.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY92562.1 - 0.00098 18.6 0.0 0.0062 16.0 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.12 ORY92562.1 - 0.0013 18.0 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 ORY92562.1 - 0.011 15.3 0.1 0.092 12.3 0.2 2.2 2 1 0 2 2 2 0 NmrA-like family AA_permease_2 PF13520.6 ORY92563.1 - 5.8e-53 180.3 43.8 7.1e-53 180.0 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY92563.1 - 1.4e-30 106.3 40.2 2e-30 105.8 40.2 1.1 1 0 0 1 1 1 1 Amino acid permease Ninjurin PF04923.12 ORY92563.1 - 0.16 11.9 1.2 0.57 10.1 1.2 2.1 1 0 0 1 1 1 0 Ninjurin Phage_holin_2_4 PF16082.5 ORY92563.1 - 7.4 6.4 5.4 12 5.7 0.1 3.1 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Cu_amine_oxid PF01179.20 ORY92564.1 - 3e-147 490.8 0.0 3.9e-147 490.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 ORY92564.1 - 3.4e-08 33.6 0.0 6.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Fungal_trans_2 PF11951.8 ORY92565.1 - 4.2e-20 71.9 0.0 7.4e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY92565.1 - 0.015 15.4 8.6 0.033 14.3 8.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Laminin_EGF PF00053.24 ORY92565.1 - 1.7 8.9 11.0 15 5.8 0.1 2.4 2 0 0 2 2 2 0 Laminin EGF domain CHCH PF06747.13 ORY92566.1 - 5.5e-07 29.6 3.1 9e-07 28.9 3.1 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 ORY92566.1 - 2e-05 24.7 1.8 2.7e-05 24.3 1.8 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 ORY92566.1 - 0.013 15.7 2.8 0.019 15.3 2.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 ORY92566.1 - 0.11 12.8 3.7 0.3 11.4 3.7 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) BRO1 PF03097.18 ORY92567.1 - 4.1e-17 62.1 0.0 5.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain Spc7 PF08317.11 ORY92569.1 - 0.00025 20.1 8.5 0.00032 19.7 8.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Mucin PF01456.17 ORY92569.1 - 0.0028 17.7 4.7 0.0036 17.3 4.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein ABC_tran_CTD PF16326.5 ORY92569.1 - 0.0033 17.6 1.2 1.5 9.1 0.2 2.7 2 1 0 2 2 2 1 ABC transporter C-terminal domain DUF3552 PF12072.8 ORY92569.1 - 0.0039 16.6 6.3 0.0055 16.1 6.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ApoLp-III PF07464.11 ORY92569.1 - 0.0041 17.2 4.6 0.0055 16.8 4.6 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) AAA_13 PF13166.6 ORY92569.1 - 0.0044 15.7 4.2 0.0057 15.4 4.2 1.1 1 0 0 1 1 1 1 AAA domain HrpB7 PF09486.10 ORY92569.1 - 0.01 16.2 8.5 0.041 14.3 8.1 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) HIP1_clath_bdg PF16515.5 ORY92569.1 - 0.012 16.2 5.9 0.73 10.5 5.9 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prominin PF05478.11 ORY92569.1 - 0.017 13.2 2.2 0.022 12.8 2.2 1.0 1 0 0 1 1 1 0 Prominin Sec10 PF07393.11 ORY92569.1 - 0.02 13.3 4.8 0.025 13.0 4.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Baculo_PEP_C PF04513.12 ORY92569.1 - 0.029 14.4 6.7 0.04 14.0 6.7 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec8_exocyst PF04048.14 ORY92569.1 - 0.029 14.3 4.2 0.63 9.9 1.1 2.2 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain BORCS8 PF10167.9 ORY92569.1 - 0.03 14.3 1.1 0.12 12.3 0.3 2.0 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 8 HMMR_N PF15905.5 ORY92569.1 - 0.047 13.2 6.4 0.066 12.7 6.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMPIT PF07851.13 ORY92569.1 - 0.054 12.7 1.0 0.067 12.4 1.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 ORY92569.1 - 0.08 13.0 9.7 0.13 12.3 9.7 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.20 ORY92569.1 - 0.11 11.9 8.3 0.38 10.1 8.3 1.7 1 1 0 1 1 1 0 Tropomyosin TssO PF17561.2 ORY92569.1 - 0.11 12.6 0.8 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO Mit_KHE1 PF10173.9 ORY92569.1 - 0.14 12.3 1.3 0.18 11.9 1.3 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related V_ATPase_I PF01496.19 ORY92569.1 - 0.14 10.0 2.5 0.17 9.8 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MetOD2 PF18548.1 ORY92569.1 - 0.14 12.3 2.2 2.4 8.3 0.2 2.6 1 1 2 3 3 3 0 Metanogen output domain 2 Fib_alpha PF08702.10 ORY92569.1 - 0.21 11.8 6.3 0.35 11.0 6.3 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1993 PF09351.10 ORY92569.1 - 0.28 11.3 4.8 0.76 9.9 4.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) CCDC158 PF15921.5 ORY92569.1 - 0.29 8.9 7.2 0.35 8.6 7.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 ApoO PF09769.9 ORY92569.1 - 0.3 11.1 7.4 0.049 13.6 3.2 1.9 2 1 1 3 3 2 0 Apolipoprotein O Fez1 PF06818.15 ORY92569.1 - 0.38 11.2 5.4 0.52 10.7 5.4 1.1 1 0 0 1 1 1 0 Fez1 DUF883 PF05957.13 ORY92569.1 - 0.39 11.4 4.8 1.2 9.8 4.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) HR1 PF02185.16 ORY92569.1 - 0.51 10.5 5.3 1.5 9.0 1.4 2.6 1 1 1 2 2 2 0 Hr1 repeat Seryl_tRNA_N PF02403.22 ORY92569.1 - 1 9.6 6.8 5.2 7.3 0.3 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CHD5 PF04420.14 ORY92569.1 - 1.4 8.7 7.6 3 7.7 7.6 1.7 1 1 0 1 1 1 0 CHD5-like protein DUF16 PF01519.16 ORY92569.1 - 1.8 9.1 5.6 15 6.1 5.6 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 XhlA PF10779.9 ORY92569.1 - 2 8.7 11.2 3.1 8.1 0.5 2.9 1 1 1 2 2 2 0 Haemolysin XhlA APG6_N PF17675.1 ORY92569.1 - 2.5 8.6 8.6 2.1 8.8 6.8 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region V-SNARE_C PF12352.8 ORY92569.1 - 4.6 7.6 7.2 8.6 6.7 0.3 2.9 4 0 0 4 4 2 0 Snare region anchored in the vesicle membrane C-terminus PAS_9 PF13426.7 ORY92570.1 - 1.7e-28 98.9 0.0 5.5e-16 58.7 0.0 3.4 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.12 ORY92570.1 - 3e-19 69.1 0.0 8.7e-13 48.4 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS PF00989.25 ORY92570.1 - 1e-18 67.3 0.0 2.5e-08 33.9 0.0 4.3 3 1 0 3 3 3 3 PAS fold GATA PF00320.27 ORY92570.1 - 2e-12 46.5 6.7 4.2e-12 45.5 6.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.10 ORY92570.1 - 4.9e-11 42.8 0.0 0.0088 16.3 0.0 3.4 3 0 0 3 3 3 3 PAS fold PAS_11 PF14598.6 ORY92570.1 - 2.3e-06 27.7 0.0 7.6e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 ORY92570.1 - 0.00037 20.4 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 2 PAS domain PknG_rubred PF16919.5 ORY92570.1 - 0.013 15.7 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain PhyH PF05721.13 ORY92571.1 - 1.8e-14 54.5 0.0 2.5e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) PTS_2-RNA PF01885.16 ORY92572.1 - 3.1e-61 206.6 0.0 3.6e-61 206.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family zf-RING_11 PF17123.5 ORY92573.1 - 0.002 17.9 0.6 0.0042 16.8 0.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY92573.1 - 0.0026 18.0 7.3 0.0046 17.3 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain ADIP PF11559.8 ORY92573.1 - 0.0057 16.7 4.3 0.0057 16.7 4.3 3.3 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding Zn_ribbon_17 PF17120.5 ORY92573.1 - 0.01 15.4 3.3 0.018 14.6 3.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 ORY92573.1 - 0.017 15.4 5.5 0.036 14.4 5.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY92573.1 - 0.05 13.6 4.5 0.11 12.6 4.4 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY92573.1 - 0.061 13.5 1.8 0.13 12.4 1.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING APC_N_CC PF16689.5 ORY92573.1 - 0.064 13.3 8.1 0.083 13.0 3.5 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain zf-C3HC4_2 PF13923.6 ORY92573.1 - 0.27 11.1 1.2 0.61 10.0 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY92573.1 - 0.32 10.9 5.6 0.59 10.1 5.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fib_alpha PF08702.10 ORY92573.1 - 0.41 10.8 11.7 0.21 11.8 1.0 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 ORY92573.1 - 0.9 9.1 10.9 0.34 10.4 2.2 3.0 1 1 2 3 3 3 0 fzo-like conserved region Baculo_PEP_C PF04513.12 ORY92573.1 - 1 9.4 4.8 2.1 8.4 2.5 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 ORY92573.1 - 1.3 6.8 17.0 0.063 11.2 8.9 1.9 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 ORY92573.1 - 1.6 8.9 50.6 0.25 11.5 24.4 3.1 1 1 2 3 3 3 0 Tropomyosin like DUF3450 PF11932.8 ORY92573.1 - 1.7 7.9 28.9 0.025 13.9 3.9 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 ORY92573.1 - 2.1 8.8 35.7 0.022 15.2 16.1 3.2 1 1 2 3 3 3 0 Fez1 zf-RING_5 PF14634.6 ORY92573.1 - 2.4 8.2 4.7 4.7 7.3 4.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF1664 PF07889.12 ORY92573.1 - 2.8 8.0 14.3 0.39 10.8 1.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Leu_zip PF15294.6 ORY92573.1 - 2.9 7.4 32.1 0.036 13.6 17.0 2.2 1 1 1 2 2 2 0 Leucine zipper FlaC_arch PF05377.11 ORY92573.1 - 2.9 8.4 15.3 8.7 6.8 0.5 4.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) YabA PF06156.13 ORY92573.1 - 4.4 8.0 20.8 8.8 7.0 3.4 3.6 2 1 1 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 ORY92573.1 - 4.6 7.3 35.2 0.22 11.5 20.2 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 ORY92573.1 - 4.8 7.7 18.1 14 6.3 5.8 3.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 BLOC1_2 PF10046.9 ORY92573.1 - 8.2 6.8 19.1 1.3 9.3 3.3 4.3 1 1 6 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.9 ORY92573.1 - 8.3 6.6 10.4 0.54 10.4 1.3 2.8 1 1 1 3 3 3 0 Golgi transport complex subunit 5 Prominin PF05478.11 ORY92573.1 - 9.4 4.0 5.5 16 3.2 5.4 1.4 1 1 0 1 1 1 0 Prominin Synaptobrevin PF00957.21 ORY92573.1 - 9.5 6.1 7.8 3.8 7.4 0.8 3.0 3 0 0 3 3 3 0 Synaptobrevin OMPdecase PF00215.24 ORY92574.1 - 2.3e-76 256.3 0.0 2.9e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2508 PF10704.9 ORY92574.1 - 0.097 12.8 0.1 0.34 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DUF3369 PF11849.8 ORY92574.1 - 0.19 11.9 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) Glyco_hydro_15 PF00723.21 ORY92575.1 - 3.2e-57 194.3 0.0 1.1e-55 189.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 F-box-like PF12937.7 ORY92576.1 - 8e-05 22.4 0.3 0.00025 20.8 0.3 1.9 1 0 0 1 1 1 1 F-box-like MCM PF00493.23 ORY92577.1 - 1.2e-97 325.4 0.3 2e-97 324.7 0.3 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY92577.1 - 5.8e-34 116.7 0.1 1.1e-33 115.8 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY92577.1 - 4.3e-23 81.5 0.9 1e-22 80.3 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY92577.1 - 3.8e-12 46.7 0.0 1.5e-11 44.8 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY92577.1 - 5.9e-08 32.3 0.1 9.3e-07 28.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY92577.1 - 0.0025 17.7 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY92577.1 - 0.009 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 ORY92577.1 - 0.098 12.7 0.0 0.4 10.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SAGA-Tad1 PF12767.7 ORY92577.1 - 1.3 8.7 4.0 2.5 7.8 4.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PRP38_assoc PF12871.7 ORY92577.1 - 1.6 9.4 16.0 5.9 7.6 16.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4611 PF15387.6 ORY92577.1 - 4.4 7.6 18.1 0.35 11.1 5.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4611) F-box-like PF12937.7 ORY92578.1 - 4e-06 26.6 0.2 8.5e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 F-box-like Ribosomal_L22 PF00237.19 ORY92579.1 - 5.5e-28 97.2 0.9 6.7e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e HRI1 PF16815.5 ORY92580.1 - 1.1e-39 136.5 0.0 1.3e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 Arginase PF00491.21 ORY92581.1 - 1.5e-86 290.4 0.0 1.9e-86 290.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family FA_desaturase PF00487.24 ORY92581.1 - 0.0022 17.9 0.1 0.0033 17.3 0.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Beta_helix PF13229.6 ORY92582.1 - 7e-09 35.7 16.2 2.2e-07 30.8 15.9 3.1 1 1 0 1 1 1 1 Right handed beta helix region SPX PF03105.19 ORY92582.1 - 5.6e-05 23.2 8.1 7.1e-05 22.9 8.1 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 ORY92582.1 - 0.00088 18.2 6.3 0.0011 17.9 6.3 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Miga PF10265.9 ORY92582.1 - 0.029 13.3 5.7 0.037 13.0 5.7 1.1 1 0 0 1 1 1 0 Mitoguardin Ndc1_Nup PF09531.10 ORY92582.1 - 0.13 10.9 11.4 0.2 10.3 11.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4667 PF15700.5 ORY92582.1 - 0.29 11.2 26.4 0.46 10.5 26.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) SOG2 PF10428.9 ORY92582.1 - 0.42 9.7 26.0 0.59 9.3 26.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NosD PF05048.13 ORY92582.1 - 1.4 8.1 16.3 0.039 13.2 2.8 3.2 2 1 1 3 3 3 0 Periplasmic copper-binding protein (NosD) GREB1 PF15782.5 ORY92582.1 - 1.7 5.6 13.2 2.2 5.3 13.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Kinesin_assoc PF16183.5 ORY92582.1 - 2.6 8.2 4.6 4.6 7.4 4.6 1.4 1 0 0 1 1 1 0 Kinesin-associated SAPS PF04499.15 ORY92582.1 - 3.2 6.4 5.7 4.3 6.0 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.13 ORY92582.1 - 5.5 6.5 10.5 7.6 6.1 10.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.15 ORY92582.1 - 6.4 6.2 6.4 9 5.8 6.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Beta_helix PF13229.6 ORY92583.1 - 2.3e-09 37.3 15.0 1e-08 35.2 11.4 2.9 1 1 1 2 2 2 1 Right handed beta helix region NosD PF05048.13 ORY92583.1 - 0.00083 18.7 6.8 0.027 13.7 2.7 2.8 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) SOG2 PF10428.9 ORY92583.1 - 0.35 10.0 6.6 0.48 9.6 6.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.18 ORY92584.1 - 3.7e-12 45.8 0.0 7e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY92584.1 - 2.4e-06 27.5 11.4 4.3e-06 26.7 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 ORY92584.1 - 3 8.4 9.1 5.6 7.5 9.1 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Beta_helix PF13229.6 ORY92585.1 - 1.6e-08 34.6 15.3 5.5e-07 29.6 15.3 3.0 1 1 0 1 1 1 1 Right handed beta helix region Apt1 PF10351.9 ORY92585.1 - 0.057 12.3 4.2 0.073 11.9 4.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.15 ORY92585.1 - 0.12 11.9 0.2 0.17 11.4 0.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SPX PF03105.19 ORY92585.1 - 0.17 11.8 6.3 0.23 11.4 6.3 1.2 1 0 0 1 1 1 0 SPX domain DUF572 PF04502.13 ORY92585.1 - 0.34 10.5 0.7 0.45 10.1 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GEMIN8 PF15348.6 ORY92585.1 - 0.74 10.1 3.6 1.1 9.5 3.6 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 NosD PF05048.13 ORY92585.1 - 0.76 9.0 14.2 0.048 12.9 1.7 3.2 2 1 1 3 3 3 0 Periplasmic copper-binding protein (NosD) Macoilin PF09726.9 ORY92585.1 - 3.2 6.2 12.6 4.2 5.8 12.6 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 ORY92585.1 - 3.7 6.4 8.7 5.7 5.8 8.7 1.2 1 0 0 1 1 1 0 Mitoguardin PCMT PF01135.19 ORY92586.1 - 2.1e-60 204.0 0.0 2.6e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORY92586.1 - 3.1e-06 27.1 0.0 4.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY92586.1 - 0.00025 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ORY92586.1 - 0.00049 20.0 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ORY92586.1 - 0.00097 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 ORY92586.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin Methyltransf_25 PF13649.6 ORY92586.1 - 0.0016 19.1 0.0 0.0035 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY92586.1 - 0.0033 17.4 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 ORY92586.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 ORY92586.1 - 0.06 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 ORY92586.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 ORY92586.1 - 0.18 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPR_2 PF07719.17 ORY92587.1 - 0.00019 21.3 8.2 0.7 10.1 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY92587.1 - 0.076 13.3 9.9 5.5 7.5 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY92587.1 - 0.13 12.2 5.2 4.7 7.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat UQ_con PF00179.26 ORY92588.1 - 4.2e-53 178.8 0.0 4.7e-53 178.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY92588.1 - 0.003 17.8 0.0 0.0036 17.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 ORY92588.1 - 0.0052 16.5 0.0 0.0065 16.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY92588.1 - 0.037 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain DPBB_1 PF03330.18 ORY92589.1 - 4.1e-08 33.4 0.1 1.2e-07 31.9 0.1 1.8 2 0 0 2 2 2 1 Lytic transglycolase F-box-like PF12937.7 ORY92590.1 - 5.6e-06 26.2 0.3 1.8e-05 24.6 0.3 2.0 1 0 0 1 1 1 1 F-box-like Phage_TAC_10 PF10963.8 ORY92590.1 - 0.13 12.5 0.0 4.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone tRNA-synt_2 PF00152.20 ORY92591.1 - 4.4e-79 265.8 0.0 6.5e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY92591.1 - 1.6e-05 24.8 0.1 5.1e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DCR PF14047.6 ORY92591.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Dppa2/4 conserved region F-box-like PF12937.7 ORY92592.1 - 0.0046 16.8 0.9 0.013 15.4 0.9 1.8 1 0 0 1 1 1 1 F-box-like ELYS PF13934.6 ORY92593.1 - 4.6e-38 131.4 0.0 8.7e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore complex assembly YL1 PF05764.13 ORY92593.1 - 0.13 12.4 28.6 0.053 13.6 12.4 2.2 2 0 0 2 2 2 0 YL1 nuclear protein AJAP1_PANP_C PF15298.6 ORY92593.1 - 1.5 9.0 20.4 1.2 9.3 9.7 2.6 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF1459 PF07312.11 ORY92593.1 - 4.3 7.6 7.0 16 5.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) 2-oxoacid_dh PF00198.23 ORY92594.1 - 5e-80 268.3 0.2 7.3e-80 267.8 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY92594.1 - 1.7e-17 63.0 0.2 3.4e-17 62.0 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ORY92594.1 - 0.017 15.0 0.2 0.12 12.2 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 ORY92594.1 - 0.07 13.8 0.1 0.53 11.0 0.1 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Presenilin PF01080.17 ORY92594.1 - 0.81 8.4 7.1 1.4 7.6 7.1 1.3 1 0 0 1 1 1 0 Presenilin GET2 PF08690.10 ORY92594.1 - 0.91 9.1 9.1 1.3 8.6 9.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Plasmodium_Vir PF05795.11 ORY92594.1 - 1.3 8.4 4.7 1.8 7.9 4.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC45 PF02724.14 ORY92594.1 - 2.6 6.2 7.7 3.3 5.9 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORY92594.1 - 4 7.2 11.4 5.5 6.7 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 F-box-like PF12937.7 ORY92595.1 - 0.006 16.4 1.8 0.013 15.4 0.8 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY92595.1 - 2.6 8.6 8.6 69 4.1 0.1 4.9 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) SANTA PF09133.10 ORY92596.1 - 3e-08 34.0 0.0 5.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 SANTA (SANT Associated) F-box-like PF12937.7 ORY92597.1 - 0.00034 20.4 2.8 0.0006 19.7 2.8 1.4 1 0 0 1 1 1 1 F-box-like PNRC PF15365.6 ORY92599.1 - 5.2e-09 35.7 5.8 5.2e-09 35.7 5.8 2.8 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif Acetyltransf_3 PF13302.7 ORY92601.1 - 2.7e-09 37.8 0.0 6.1e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ribosomal_60s PF00428.19 ORY92601.1 - 0.087 13.4 0.1 0.15 12.6 0.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.7 ORY92602.1 - 0.00056 19.7 0.5 0.0015 18.4 0.5 1.7 1 0 0 1 1 1 1 F-box-like Bud13 PF09736.9 ORY92603.1 - 8.3e-51 172.2 10.4 8.3e-51 172.2 10.4 2.5 1 1 1 2 2 2 1 Pre-mRNA-splicing factor of RES complex Peptidase_M50B PF13398.6 ORY92604.1 - 5.7e-46 156.7 12.7 6.7e-46 156.4 12.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like AhpC-TSA_2 PF13911.6 ORY92605.1 - 2.9e-20 72.5 0.0 3.9e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 ORY92605.1 - 1.5e-05 24.9 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY92605.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin GST_N_2 PF13409.6 ORY92606.1 - 8.3e-21 74.1 0.0 4.5e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY92606.1 - 4.9e-14 52.1 0.0 8.5e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY92606.1 - 3.1e-05 24.3 0.0 0.071 13.5 0.0 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY92606.1 - 7e-05 23.0 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY92606.1 - 0.00019 21.6 0.0 0.00036 20.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cas9_REC PF16592.5 ORY92606.1 - 0.074 11.8 0.0 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 STT3 PF02516.14 ORY92607.1 - 4.3e-136 454.7 31.5 5.1e-134 447.9 31.5 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Thioredoxin PF00085.20 ORY92608.1 - 4.4e-33 113.3 0.1 1.6e-26 92.3 0.0 2.3 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 ORY92608.1 - 1.9e-11 44.3 0.4 6.8e-06 26.5 0.1 2.7 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY92608.1 - 8.4e-08 32.4 0.0 0.0017 18.6 0.0 2.8 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 ORY92608.1 - 6.4e-05 22.5 0.0 0.0017 17.7 0.0 2.1 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 ORY92608.1 - 0.00022 21.1 0.3 0.0019 18.1 0.1 2.2 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_6 PF13848.6 ORY92608.1 - 0.00034 20.6 0.0 0.0013 18.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 ORY92608.1 - 0.0034 17.4 0.1 1.9 8.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.6 ORY92608.1 - 0.0077 16.1 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 ORY92608.1 - 0.013 15.3 0.0 0.13 12.0 0.0 2.2 3 0 0 3 3 3 0 Thioredoxin Calsequestrin PF01216.17 ORY92608.1 - 0.017 14.2 0.1 0.6 9.1 0.1 2.1 1 1 1 2 2 2 0 Calsequestrin Redoxin PF08534.10 ORY92608.1 - 0.022 14.5 1.0 1.7 8.4 0.2 2.2 1 1 1 2 2 2 0 Redoxin HyaE PF07449.11 ORY92608.1 - 0.032 14.2 0.0 0.23 11.4 0.0 2.2 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 ORY92608.1 - 0.035 14.3 1.0 9.1 6.6 0.9 2.6 2 1 0 2 2 2 0 Glutaredoxin TrbC_Ftype PF09673.10 ORY92608.1 - 0.11 12.5 0.0 0.69 10.0 0.0 1.9 1 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein F-box-like PF12937.7 ORY92609.1 - 3.5e-05 23.6 2.4 3.5e-05 23.6 2.4 1.9 2 0 0 2 2 2 1 F-box-like HTH_DeoR PF08220.12 ORY92609.1 - 0.0042 16.8 0.2 0.0091 15.7 0.2 1.5 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain LRR_8 PF13855.6 ORY92609.1 - 0.014 15.2 4.2 1.7 8.5 0.0 3.7 4 1 0 4 4 4 0 Leucine rich repeat Sigma70_r4_2 PF08281.12 ORY92609.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DprA_WH PF17782.1 ORY92609.1 - 8.5 6.6 7.7 1.5 9.0 0.2 2.9 3 0 0 3 3 3 0 DprA winged helix domain Ubiq_cyt_C_chap PF03981.12 ORY92610.1 - 1.2e-26 93.5 0.0 9.5e-26 90.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone F-box-like PF12937.7 ORY92613.1 - 7.9e-07 28.9 2.8 1.3e-06 28.2 2.8 1.4 1 0 0 1 1 1 1 F-box-like Zn_ribbon_SprT PF17283.2 ORY92613.1 - 0.16 11.9 10.2 0.36 10.8 10.2 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain F-box-like PF12937.7 ORY92614.1 - 0.0098 15.8 0.9 0.033 14.1 0.9 2.0 1 0 0 1 1 1 1 F-box-like SAMP PF05924.11 ORY92614.1 - 0.011 14.9 0.5 0.026 13.8 0.5 1.5 1 0 0 1 1 1 0 SAMP Motif F-box PF00646.33 ORY92614.1 - 0.082 12.8 0.4 1.4 8.9 0.4 2.7 1 1 0 1 1 1 0 F-box domain Zn_clus PF00172.18 ORY92615.1 - 0.00036 20.6 7.9 0.00054 20.0 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_16 PF00722.21 ORY92616.1 - 2.7e-05 23.7 0.0 6.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CDC45 PF02724.14 ORY92616.1 - 0.04 12.2 5.4 0.05 11.9 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RAMP4 PF06624.12 ORY92616.1 - 0.17 12.0 0.0 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Dynactin_p62 PF05502.13 ORY92617.1 - 5e-78 263.0 2.4 1.3e-47 162.7 6.7 2.1 2 0 0 2 2 2 2 Dynactin p62 family zf-ribbon_3 PF13248.6 ORY92617.1 - 0.21 11.0 0.1 0.21 11.0 0.1 4.5 5 0 0 5 5 5 0 zinc-ribbon domain Tim44 PF04280.15 ORY92618.1 - 4.1e-13 49.7 0.5 5.8e-13 49.2 0.5 1.2 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 ORY92618.1 - 2e-05 23.8 0.1 2.9e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 MBA1-like protein NAGLU PF05089.12 ORY92618.1 - 0.083 11.8 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain MA3 PF02847.17 ORY92618.1 - 0.16 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 MA3 domain 4HBT PF03061.22 ORY92619.1 - 1.3e-22 79.9 0.4 1.4e-12 47.8 0.0 2.8 3 0 0 3 3 3 2 Thioesterase superfamily Phage_Mu_F PF04233.14 ORY92620.1 - 0.061 14.1 0.0 0.11 13.3 0.0 1.3 1 0 0 1 1 1 0 Phage Mu protein F like protein VPS9 PF02204.18 ORY92621.1 - 0.019 15.2 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain DUF3652 PF12372.8 ORY92621.1 - 0.1 12.5 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 Huntingtin protein region Histone PF00125.24 ORY92623.1 - 7.1e-14 52.3 0.2 8.7e-14 52.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92623.1 - 4.7e-05 23.6 0.5 6.7e-05 23.1 0.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY92623.1 - 0.00016 22.1 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 ORY92623.1 - 0.016 15.3 0.0 0.018 15.1 0.0 1.1 1 0 0 1 1 1 0 YscO-like protein DUF1931 PF09123.11 ORY92623.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) PX PF00787.24 ORY92624.1 - 1.5e-15 57.2 0.0 4.1e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 PX domain AhpC-TSA PF00578.21 ORY92624.1 - 0.23 11.4 0.0 0.43 10.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family F-box-like PF12937.7 ORY92625.1 - 0.0025 17.7 0.1 0.0042 16.9 0.1 1.4 1 0 0 1 1 1 1 F-box-like TRM13 PF05206.14 ORY92625.1 - 0.054 13.0 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 LRR_8 PF13855.6 ORY92627.1 - 0.0011 18.7 0.5 0.039 13.7 0.0 3.2 3 0 0 3 3 3 1 Leucine rich repeat F-box-like PF12937.7 ORY92627.1 - 0.0043 16.9 3.7 0.01 15.7 0.6 2.7 2 0 0 2 2 2 1 F-box-like RabGAP-TBC PF00566.18 ORY92628.1 - 0.26 10.9 2.7 0.42 10.2 2.7 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain ESSS PF10183.9 ORY92629.1 - 0.12 12.6 0.3 16 5.8 0.0 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Insulin_TMD PF17870.1 ORY92629.1 - 0.26 11.4 6.8 0.95 9.6 0.5 2.5 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Abhydrolase_3 PF07859.13 ORY92630.1 - 1.8e-29 103.1 0.0 2.3e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY92630.1 - 1.2e-13 50.7 0.0 2.3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ORY92630.1 - 1.8e-05 24.2 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY92630.1 - 0.00036 21.2 0.7 0.00052 20.7 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORY92630.1 - 0.00098 19.0 0.0 0.002 17.9 0.0 1.5 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ORY92630.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ORY92630.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2156 PF09924.9 ORY92631.1 - 6.2e-25 87.8 0.0 7.1e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) HMG_CoA_synt_N PF01154.17 ORY92633.1 - 9.1e-89 295.9 0.1 1.3e-88 295.4 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 ORY92633.1 - 1e-88 297.6 0.3 1.3e-88 297.3 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 ORY92633.1 - 0.0088 15.9 0.1 0.02 14.8 0.1 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 ORY92633.1 - 0.013 15.6 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal PMT PF02366.18 ORY92634.1 - 2.7e-85 285.9 14.3 4.5e-85 285.1 14.3 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY92634.1 - 6e-64 215.3 2.2 6e-64 215.3 2.2 3.2 3 0 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY92634.1 - 1.1e-15 57.9 4.0 1.8e-15 57.3 4.0 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 ORY92634.1 - 7.4e-07 29.5 8.0 7.4e-07 29.5 8.0 2.7 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1240 PF06836.12 ORY92634.1 - 8 7.1 6.1 2.1 8.9 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) DUF4042 PF13251.6 ORY92635.1 - 2.8e-30 105.4 0.3 3.1e-29 102.0 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 ORY92635.1 - 2.3e-09 37.6 18.4 0.0031 18.0 0.2 7.4 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 ORY92635.1 - 9.8e-08 32.3 13.6 0.11 12.9 0.3 6.4 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.22 ORY92635.1 - 2.6e-07 30.3 21.8 0.059 13.7 0.2 8.3 9 0 0 9 9 9 2 HEAT repeat IFRD PF05004.13 ORY92635.1 - 1.8 7.6 13.4 0.013 14.6 2.2 2.8 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) RabGAP-TBC PF00566.18 ORY92636.1 - 2.6e-28 99.2 0.0 3.5e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cyt-b5 PF00173.28 ORY92637.1 - 1.2e-10 41.4 0.4 1.3e-10 41.2 0.4 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M43 PF05572.13 ORY92638.1 - 1.1e-10 41.6 0.0 1.8e-10 40.9 0.0 1.3 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 ORY92638.1 - 0.0054 16.9 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 ORY92638.1 - 0.013 14.7 0.1 0.021 14.0 0.1 1.2 1 0 0 1 1 1 0 Met-zincin Peptidase_M10 PF00413.24 ORY92638.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.2 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 ORY92638.1 - 0.028 14.9 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORY92638.1 - 0.037 13.7 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 ORY92638.1 - 0.13 11.9 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Ribosomal_L28 PF00830.19 ORY92640.1 - 8.4e-19 67.5 0.1 1.5e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family F-box-like PF12937.7 ORY92641.1 - 0.00023 21.0 0.9 0.00041 20.2 0.9 1.5 1 0 0 1 1 1 1 F-box-like SIR2 PF02146.17 ORY92642.1 - 7.2e-57 192.1 0.0 2.1e-56 190.6 0.0 1.7 2 0 0 2 2 2 1 Sir2 family Methyltransf_23 PF13489.6 ORY92643.1 - 8.3e-23 81.0 0.0 1.3e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY92643.1 - 1.4e-15 57.7 0.0 1.5e-14 54.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY92643.1 - 3.4e-12 46.9 0.1 1.1e-09 38.9 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY92643.1 - 5.9e-11 43.0 0.0 9.9e-10 39.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY92643.1 - 1.3e-09 38.0 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.13 ORY92643.1 - 3e-06 26.9 0.1 5.4e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 ORY92643.1 - 0.00015 21.2 0.0 0.077 12.3 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 ORY92643.1 - 0.013 14.4 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) MTS PF05175.14 ORY92643.1 - 0.021 14.4 0.2 0.24 10.9 0.1 2.1 1 1 0 2 2 2 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 ORY92643.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 ORY92643.1 - 0.19 11.0 0.0 1.5 8.1 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family NodS PF05401.11 ORY92643.1 - 0.21 11.2 0.0 1.7 8.2 0.0 2.0 2 0 0 2 2 2 0 Nodulation protein S (NodS) Cyt-b5 PF00173.28 ORY92644.1 - 4.6e-11 42.7 0.1 6.5e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mcp5_PH PF12814.7 ORY92645.1 - 2.1e-45 153.7 0.1 4.7e-45 152.6 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 ORY92645.1 - 0.00035 21.0 0.0 0.00077 19.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Sec3_C_2 PF15278.6 ORY92645.1 - 3.2 8.1 5.1 4.3 7.7 0.1 2.8 2 0 0 2 2 2 0 Sec3 exocyst complex subunit DNA_primase_S PF01896.19 ORY92646.1 - 1.6e-57 194.4 0.2 2.5e-57 193.7 0.2 1.2 1 0 0 1 1 1 1 DNA primase small subunit AMP-binding PF00501.28 ORY92647.1 - 1.7e-88 297.0 0.0 2e-88 296.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY92647.1 - 1e-12 48.9 0.7 3.7e-12 47.1 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sds3 PF08598.11 ORY92648.1 - 2.9e-24 86.3 0.3 2.9e-24 86.3 0.3 2.1 2 0 0 2 2 2 1 Sds3-like Glyco_hydro_16 PF00722.21 ORY92649.1 - 9.4e-07 28.5 0.0 2.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FAM70 PF14967.6 ORY92649.1 - 0.37 10.2 5.9 0.53 9.7 5.9 1.2 1 0 0 1 1 1 0 FAM70 protein Glyco_hydro_16 PF00722.21 ORY92650.1 - 4.9e-06 26.1 0.0 2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF5360 PF17314.2 ORY92650.1 - 0.087 12.9 5.8 4.7 7.3 0.3 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5360) Isy1 PF06246.12 ORY92651.1 - 0.091 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Isy1-like splicing family VPS9 PF02204.18 ORY92652.1 - 8.8e-31 106.2 0.0 1.6e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.16 ORY92652.1 - 2.8e-11 42.9 0.1 5.7e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF5601 PF18151.1 ORY92652.1 - 1.7e-08 34.6 0.1 9.6e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) DMA PF03474.14 ORY92652.1 - 0.0041 16.7 0.0 0.0087 15.6 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif F-box-like PF12937.7 ORY92653.1 - 6.1e-05 22.8 2.0 0.00024 20.9 1.5 2.2 2 0 0 2 2 2 1 F-box-like FSA_C PF10479.9 ORY92654.1 - 4.7 5.2 10.9 7.3 4.6 10.9 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HECT_2 PF09814.9 ORY92655.1 - 1.3e-41 142.8 0.0 2.2e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.14 ORY92655.1 - 0.00071 19.8 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Bestrophin PF01062.21 ORY92657.1 - 1.7e-25 90.0 0.1 1.5e-15 57.4 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Fasciclin PF02469.22 ORY92658.1 - 5.7e-19 68.6 0.0 7.4e-09 35.9 0.0 4.2 4 0 0 4 4 4 3 Fasciclin domain PfkB PF00294.24 ORY92659.1 - 8.2e-14 51.6 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORY92659.1 - 0.067 12.6 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase BAG PF02179.16 ORY92660.1 - 2.6e-09 37.4 0.0 2.6e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 BAG domain Histone_HNS PF00816.21 ORY92660.1 - 2.7 8.8 9.4 1.7 9.5 4.9 2.7 2 1 0 2 2 2 0 H-NS histone family F-box-like PF12937.7 ORY92662.1 - 2.1e-05 24.3 2.6 8.1e-05 22.4 2.0 2.3 2 0 0 2 2 2 1 F-box-like DUF3613 PF12266.8 ORY92663.1 - 0.7 9.7 3.9 0.21 11.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) PrpF PF04303.13 ORY92664.1 - 2.1e-31 109.2 2.1 4.5e-19 68.7 0.1 3.4 2 1 0 2 2 2 2 PrpF protein WD40 PF00400.32 ORY92665.1 - 2.4e-41 138.9 20.2 3.9e-08 33.8 0.1 12.4 14 0 0 14 14 14 8 WD domain, G-beta repeat Utp12 PF04003.12 ORY92665.1 - 4.4e-24 84.8 0.0 8e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 ORY92665.1 - 3.4e-20 72.1 0.0 0.042 14.2 0.1 9.5 3 2 8 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY92665.1 - 5.4e-08 32.2 2.4 0.97 8.3 0.1 6.6 4 3 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY92665.1 - 6.6e-06 26.1 0.4 0.41 10.5 0.1 4.7 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY92665.1 - 0.0031 16.9 0.2 0.15 11.3 0.0 3.7 6 0 0 6 6 6 1 WD40-like domain ELYS-bb PF16687.5 ORY92665.1 - 0.032 12.9 0.0 0.095 11.3 0.0 1.7 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin PD40 PF07676.12 ORY92665.1 - 0.12 12.4 0.0 35 4.5 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RCC1_2 PF13540.6 ORY92665.1 - 0.22 11.4 1.0 9.6 6.1 0.0 3.6 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat Cytochrom_D1 PF02239.16 ORY92665.1 - 1 7.8 3.3 37 2.7 0.3 3.5 4 1 0 4 4 4 0 Cytochrome D1 heme domain Metallophos PF00149.28 ORY92666.1 - 3.2e-40 138.8 0.1 4.3e-40 138.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY92666.1 - 8.3e-22 77.4 1.2 1.4e-21 76.7 0.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Sugar_tr PF00083.24 ORY92668.1 - 2.8e-101 339.6 30.2 3.3e-101 339.4 30.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY92668.1 - 1.2e-22 80.3 36.8 1.2e-22 80.3 36.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hydrolase_6 PF13344.6 ORY92669.1 - 2.1e-13 50.3 0.1 2.8e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase F-box PF00646.33 ORY92670.1 - 0.00026 20.8 1.2 0.0013 18.6 0.1 2.5 3 0 0 3 3 3 1 F-box domain F-box_4 PF15966.5 ORY92670.1 - 0.0016 18.3 0.1 0.0034 17.2 0.1 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 ORY92670.1 - 0.014 15.3 3.3 0.019 14.8 0.3 2.6 3 0 0 3 3 3 0 F-box-like AFG1_ATPase PF03969.16 ORY92671.1 - 2.5e-89 299.7 0.0 3.2e-84 282.9 0.0 3.1 2 1 0 3 3 3 3 AFG1-like ATPase AAA_16 PF13191.6 ORY92671.1 - 6.1e-05 23.5 0.4 0.077 13.4 0.2 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 ORY92671.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY92671.1 - 0.005 17.1 0.0 0.033 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY92671.1 - 0.011 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY92671.1 - 0.012 16.0 0.0 0.034 14.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY92671.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 ORY92671.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cwf21 PF08312.12 ORY92672.1 - 1.8e-16 60.0 9.7 1.8e-16 60.0 9.7 2.7 3 1 0 3 3 3 1 cwf21 domain Gelsolin PF00626.22 ORY92673.1 - 2.5e-34 117.0 0.0 9e-13 47.9 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat MFS_1 PF07690.16 ORY92674.1 - 9.5e-43 146.5 44.2 1.2e-40 139.5 44.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Gly_transf_sug PF04488.15 ORY92675.1 - 3.6e-06 27.5 0.0 6.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY92675.1 - 0.35 10.2 1.2 0.59 9.5 1.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Hydrolase_6 PF13344.6 ORY92676.1 - 1.4e-29 102.1 0.0 2.4e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY92676.1 - 1.7e-21 76.0 0.0 4.6e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY92676.1 - 2.8e-10 40.8 0.0 4e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY92676.1 - 7.3e-06 26.2 0.0 0.00012 22.2 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 ORY92677.1 - 3.2e-109 365.8 20.7 3.8e-109 365.6 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY92677.1 - 1.9e-19 69.8 37.0 1.9e-18 66.5 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 ORY92678.1 - 7.5e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY92678.1 - 2.6e-11 43.0 0.0 3.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY92678.1 - 9.6e-08 32.1 0.1 1.9e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY92678.1 - 4.1e-07 29.7 0.0 8.7e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY92678.1 - 7.5e-07 28.6 0.0 6.2e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 ORY92678.1 - 0.00014 21.4 0.1 0.00063 19.2 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 ORY92678.1 - 0.00018 21.1 0.3 0.00038 20.1 0.3 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY92678.1 - 0.014 14.6 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PDEase_I PF00233.19 ORY92679.1 - 3.3e-62 210.3 0.0 2.8e-61 207.3 0.0 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase SPX PF03105.19 ORY92679.1 - 1.8 8.4 19.7 0.17 11.8 5.7 2.3 2 0 0 2 2 2 0 SPX domain Nucleoporin2 PF04096.14 ORY92680.1 - 1e-44 152.3 0.0 1.6e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 ORY92680.1 - 1.3e-20 74.0 245.7 3.6e-08 34.1 28.3 11.4 3 3 6 9 9 9 6 Nucleoporin FG repeat region Brr6_like_C_C PF10104.9 ORY92681.1 - 3.8e-38 130.3 0.2 4.7e-38 130.0 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Abhydrolase_9_N PF15420.6 ORY92682.1 - 0.0087 16.1 3.4 0.0087 16.1 3.4 2.8 3 1 1 4 4 4 2 Alpha/beta-hydrolase family N-terminus APG6_N PF17675.1 ORY92684.1 - 0.29 11.6 8.5 0.061 13.9 3.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region TMPIT PF07851.13 ORY92684.1 - 0.42 9.8 2.0 4 6.6 0.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 ORY92684.1 - 0.8 9.9 6.9 0.21 11.8 1.0 2.3 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 COG5 PF10392.9 ORY92684.1 - 0.93 9.7 5.4 1.4 9.1 0.1 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 BLOC1_2 PF10046.9 ORY92684.1 - 1 9.7 4.8 0.67 10.3 2.2 2.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF148 PF02520.17 ORY92684.1 - 1.5 9.0 9.6 1.8 8.7 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 UPF0242 PF06785.11 ORY92684.1 - 1.6 8.8 6.6 0.31 11.1 1.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_HK97_TLTM PF06120.11 ORY92684.1 - 1.8 7.7 6.5 0.77 8.9 0.8 2.1 2 0 0 2 2 2 0 Tail length tape measure protein PIGA PF08288.12 ORY92685.1 - 1.7e-32 111.8 0.2 4.7e-32 110.4 0.2 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 ORY92685.1 - 1.9e-28 99.6 2.3 3.2e-28 98.9 2.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ORY92685.1 - 3.1e-25 88.7 0.0 5.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY92685.1 - 6e-24 85.0 0.1 1.3e-23 83.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY92685.1 - 2.8e-16 60.4 1.4 4.1e-16 59.8 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 ORY92685.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 ORY92685.1 - 5.1e-06 26.8 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 ORY92685.1 - 0.00015 21.6 0.0 0.0014 18.4 0.0 2.1 1 1 0 1 1 1 1 Starch synthase catalytic domain Ysc84 PF04366.12 ORY92686.1 - 8.3e-38 129.0 0.1 1.2e-37 128.5 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Histone_H2A_C PF16211.5 ORY92687.1 - 1.1e-18 66.6 0.9 2.2e-18 65.7 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY92687.1 - 1.5e-17 64.1 0.0 2e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92687.1 - 5.2e-05 23.4 0.0 9.5e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY92688.1 - 2.1e-21 76.7 1.7 2.5e-21 76.4 1.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92688.1 - 2.7e-05 24.4 0.0 7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY92688.1 - 0.0033 17.9 0.0 0.0052 17.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 ORY92688.1 - 0.02 15.1 0.1 0.038 14.2 0.0 1.5 1 1 0 1 1 1 0 CENP-W protein DUF5539 PF17693.1 ORY92688.1 - 0.071 12.8 1.0 0.096 12.3 1.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) DIOX_N PF14226.6 ORY92689.1 - 1.1e-10 42.2 0.0 1.9e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY92689.1 - 1.4e-10 41.6 0.0 3.6e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily A_deaminase PF00962.22 ORY92691.1 - 3.1e-122 408.0 0.1 4.8e-122 407.4 0.1 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase RSN1_7TM PF02714.15 ORY92692.1 - 3.8e-69 233.1 28.0 1.8e-67 227.6 28.0 2.3 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY92692.1 - 1.7e-29 103.3 0.0 2.4e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORY92692.1 - 6.5e-16 58.3 0.3 1.7e-15 57.0 0.0 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUF1201 PF06716.11 ORY92692.1 - 3.9 7.6 6.7 0.88 9.6 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) CAP_GLY PF01302.25 ORY92694.1 - 3.7e-23 81.3 0.2 6.1e-23 80.6 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 ORY92694.1 - 2.8e-17 63.0 0.1 2.9e-16 59.7 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 ORY92694.1 - 0.0013 18.4 0.1 1.6 8.5 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin family Cys_Met_Meta_PP PF01053.20 ORY92695.1 - 1.6e-19 69.7 0.0 2.6e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY92695.1 - 0.0095 15.1 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Ricin_B_lectin PF00652.22 ORY92695.1 - 0.24 11.7 0.0 0.41 10.9 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DNA_ligase_A_M PF01068.21 ORY92696.1 - 1.1e-24 87.3 0.0 2.4e-24 86.1 0.0 1.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY92696.1 - 1.9e-07 31.6 0.0 4.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 ORY92696.1 - 0.00095 19.5 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA ligase Glycos_transf_2 PF00535.26 ORY92697.1 - 1.6e-22 80.1 0.0 2.2e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY92697.1 - 3.7e-06 27.0 0.1 1.6e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORY92697.1 - 0.021 14.3 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Pribosyltran PF00156.27 ORY92697.1 - 0.058 12.9 0.1 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Smoothelin PF12510.8 ORY92697.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein Glyco_tranf_2_4 PF13704.6 ORY92697.1 - 0.16 12.5 0.0 0.36 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 LOR PF04525.12 ORY92698.1 - 7.9e-25 87.5 0.3 9.5e-25 87.3 0.3 1.0 1 0 0 1 1 1 1 LURP-one-related Scramblase PF03803.15 ORY92698.1 - 0.00027 20.3 1.2 0.00081 18.8 0.5 1.9 1 1 1 2 2 2 1 Scramblase RhoGAP PF00620.27 ORY92699.1 - 3e-37 127.8 0.0 6.2e-37 126.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY92699.1 - 4.3e-24 84.5 31.4 8.4e-11 41.9 2.4 5.0 6 0 0 6 6 6 4 LIM domain Flavi_NS1 PF00948.21 ORY92699.1 - 0.27 10.0 1.4 0.31 9.9 0.4 1.5 2 0 0 2 2 2 0 Flavivirus non-structural Protein NS1 zf-C2H2 PF00096.26 ORY92699.1 - 2.7 8.6 8.5 24 5.6 0.2 4.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type WD40 PF00400.32 ORY92700.1 - 2.6e-18 66.0 7.7 0.00037 21.2 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92700.1 - 2.5e-17 62.9 1.4 1.9e-06 28.1 0.1 4.2 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY92700.1 - 0.015 14.7 0.0 0.052 12.9 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Kelch_4 PF13418.6 ORY92701.1 - 7.4e-26 89.9 9.6 1.4e-07 31.4 0.0 6.4 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY92701.1 - 7.4e-23 80.3 9.2 2.5e-05 24.4 0.0 7.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY92701.1 - 5.1e-21 74.2 5.8 8.6e-06 25.6 0.0 5.8 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 ORY92701.1 - 7.7e-18 64.4 0.4 7.7e-18 64.4 0.4 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 ORY92701.1 - 3.4e-16 58.9 7.1 0.00028 21.1 0.1 5.5 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 ORY92701.1 - 1.6e-13 50.0 10.0 1.4e-05 24.8 0.2 5.7 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORY92701.1 - 5.7e-13 48.2 2.8 9.7e-05 21.9 0.0 4.8 5 1 0 5 5 5 3 Kelch motif MFS_1 PF07690.16 ORY92702.1 - 3e-34 118.5 24.5 3e-34 118.5 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY92702.1 - 4.6e-13 48.8 0.1 4.6e-13 48.8 0.1 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Aldedh PF00171.22 ORY92703.1 - 2.7e-175 583.3 0.7 3.1e-175 583.2 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Histone_H2A_C PF16211.5 ORY92704.1 - 6.2e-14 51.4 0.1 1.1e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY92704.1 - 1.4e-12 48.1 0.0 2.9e-12 47.1 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF4477 PF14780.6 ORY92705.1 - 0.0011 18.6 2.0 0.022 14.4 2.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4477) DUF5520 PF17658.1 ORY92705.1 - 0.43 9.6 4.9 0.61 9.1 4.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) NMD3 PF04981.13 ORY92706.1 - 2.8e-79 266.0 1.3 3.8e-79 265.6 1.3 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 ORY92706.1 - 0.021 14.8 7.6 3.1 7.9 7.6 2.9 1 1 0 1 1 1 0 Double zinc ribbon NinF PF05810.12 ORY92706.1 - 0.063 13.2 2.2 0.34 10.8 0.1 2.6 2 0 0 2 2 2 0 NinF protein DUF1289 PF06945.13 ORY92706.1 - 0.12 12.2 0.7 4.4 7.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) HypA PF01155.19 ORY92706.1 - 0.34 10.9 1.8 1.1 9.3 0.3 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GRAB PF10375.9 ORY92707.1 - 1.6e-05 24.6 2.1 3.2e-05 23.6 2.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Cep57_MT_bd PF06657.13 ORY92707.1 - 0.00064 20.1 4.7 0.00064 20.1 4.7 4.5 2 1 3 5 5 5 1 Centrosome microtubule-binding domain of Cep57 Arteri_nsp7a PF16749.5 ORY92707.1 - 0.16 12.2 1.3 0.38 10.9 1.3 1.6 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha ERM PF00769.19 ORY92707.1 - 1.3 8.8 53.6 1.3 8.8 30.4 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CALCOCO1 PF07888.11 ORY92707.1 - 1.3 7.8 46.3 0.031 13.2 34.9 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 ORY92707.1 - 1.4 8.9 11.2 1.9 8.5 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2285 PF10074.9 ORY92707.1 - 2.9 8.6 14.0 0.34 11.6 4.4 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2285) FlaC_arch PF05377.11 ORY92707.1 - 5.2 7.5 11.2 7.7 7.0 0.1 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) SNF2_N PF00176.23 ORY92708.1 - 2.5e-47 161.3 0.0 4.2e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY92708.1 - 4.8e-07 30.1 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY92708.1 - 4.7e-05 23.2 0.0 9.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Homoserine_dh PF00742.19 ORY92709.1 - 1.2e-46 158.8 0.0 1.7e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ORY92709.1 - 3.6e-12 47.0 0.0 6.6e-11 42.9 0.0 2.8 2 1 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain STE2 PF02116.15 ORY92710.1 - 0.0088 15.4 8.4 0.015 14.7 8.4 1.4 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Phage_holin_5_2 PF16079.5 ORY92710.1 - 0.03 14.7 6.3 3.2 8.1 1.5 2.7 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Myb_DNA-binding PF00249.31 ORY92711.1 - 1.6e-11 44.2 0.1 0.00027 21.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY92711.1 - 0.00058 20.1 0.1 0.96 9.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY92711.1 - 0.17 11.8 0.1 5.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like AIM3 PF17096.5 ORY92712.1 - 1.4 9.9 7.9 2.9 8.9 0.2 2.7 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 3 Aldedh PF00171.22 ORY92713.1 - 3.3e-16 58.9 1.1 7.8e-15 54.3 1.1 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Histone PF00125.24 ORY92714.1 - 5.2e-12 46.3 0.0 5.7e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 ORY92714.1 - 1.2e-09 37.7 0.2 1.8e-09 37.1 0.2 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 ORY92714.1 - 0.00013 22.2 0.0 0.00015 22.0 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2325 PF10087.9 ORY92715.1 - 0.028 14.5 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) HIG_1_N PF04588.13 ORY92716.1 - 4.5e-19 68.4 0.9 5.9e-19 68.0 0.9 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region CxC7 PF18866.1 ORY92716.1 - 0.1 12.7 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases DUF2613 PF11021.8 ORY92716.1 - 0.12 12.5 2.4 1.7 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF883 PF05957.13 ORY92716.1 - 0.44 11.2 5.7 0.65 10.6 0.0 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) HSP70 PF00012.20 ORY92717.1 - 6e-81 272.4 0.7 6e-81 272.4 0.7 1.3 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORY92717.1 - 6.8e-08 31.7 0.2 1.4e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 ORY92717.1 - 9.9e-07 27.7 3.6 2.2e-05 23.3 0.1 2.9 3 0 0 3 3 3 2 Actin Histone_H2A_C PF16211.5 ORY92719.1 - 5e-17 61.3 0.6 5e-17 61.3 0.6 2.2 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 ORY92719.1 - 1.4e-16 61.0 0.8 7.8e-15 55.4 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92719.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PH PF00169.29 ORY92721.1 - 0.028 14.9 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 PH domain EXS PF03124.14 ORY92722.1 - 2.1e-74 250.8 24.5 2.7e-74 250.5 24.5 1.1 1 0 0 1 1 1 1 EXS family Cwf_Cwc_15 PF04889.12 ORY92722.1 - 0.11 12.2 7.9 0.17 11.6 7.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF21 PF01595.20 ORY92722.1 - 0.27 10.9 1.6 0.51 10.0 1.6 1.4 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain RNA_pol_3_Rpc31 PF11705.8 ORY92722.1 - 0.68 10.1 12.9 1.1 9.5 12.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3169 PF11368.8 ORY92722.1 - 2.7 7.4 5.3 0.38 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) CENP-B_dimeris PF09026.10 ORY92722.1 - 3.8 8.0 18.9 11 6.5 7.4 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain BUD22 PF09073.10 ORY92722.1 - 4.4 6.5 14.2 6.3 6.0 14.2 1.1 1 0 0 1 1 1 0 BUD22 BAG PF02179.16 ORY92723.1 - 2.7e-07 30.9 0.0 2.7e-07 30.9 0.0 3.1 2 1 1 3 3 3 1 BAG domain ALMT PF11744.8 ORY92723.1 - 1.2 7.9 2.6 1.6 7.5 2.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Piezo_RRas_bdg PF12166.8 ORY92723.1 - 2.4 7.3 4.3 0.79 8.9 1.2 1.7 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain Rpn3_C PF08375.11 ORY92724.1 - 2.1e-27 95.3 1.2 2.1e-27 95.3 1.2 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 ORY92724.1 - 5.8e-22 78.2 0.1 1.4e-21 77.0 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 ORY92724.1 - 0.043 13.9 2.7 0.087 13.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY92724.1 - 0.47 10.8 6.0 9.2 6.6 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HSCB_C PF07743.13 ORY92724.1 - 5.3 7.6 6.8 4.4 7.9 0.8 2.8 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Ribophorin_II PF05817.14 ORY92725.1 - 5.7e-17 61.5 0.0 7e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II SPW PF03779.14 ORY92725.1 - 4.9 6.8 7.7 0.31 10.7 2.0 2.0 2 0 0 2 2 2 0 SPW repeat DEAD PF00270.29 ORY92726.1 - 3.9e-43 147.2 0.1 5.8e-43 146.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY92726.1 - 5e-27 94.4 0.9 1.1e-26 93.4 0.4 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY92726.1 - 3.4e-05 23.9 0.0 6.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1631 PF07793.11 ORY92727.1 - 0.21 10.0 0.4 0.27 9.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) SelP_N PF04592.14 ORY92727.1 - 8.9 5.6 8.5 12 5.2 8.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BAG PF02179.16 ORY92728.1 - 8.5e-08 32.5 0.0 8.5e-08 32.5 0.0 3.0 2 1 0 2 2 2 1 BAG domain Piezo_RRas_bdg PF12166.8 ORY92728.1 - 2.5 7.3 7.2 0.44 9.8 2.6 1.8 2 0 0 2 2 2 0 Piezo non-specific cation channel, R-Ras-binding domain YjbH PF06082.11 ORY92728.1 - 4.8 5.9 10.4 8 5.1 10.4 1.3 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF4553 PF15090.6 ORY92728.1 - 5.9 5.8 16.7 0.22 10.5 10.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4553) Hydrolase_3 PF08282.12 ORY92729.1 - 4.6e-46 157.6 0.0 5.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY92729.1 - 2e-12 47.2 0.0 2.4e-08 33.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ORY92729.1 - 7.5e-05 23.1 0.4 0.034 14.4 0.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY92729.1 - 0.13 12.6 0.3 16 5.8 0.0 3.1 2 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase SDA1 PF05285.12 ORY92730.1 - 0.15 11.4 1.8 0.23 10.9 1.8 1.3 1 0 0 1 1 1 0 SDA1 ADH_zinc_N PF00107.26 ORY92733.1 - 3e-28 98.4 0.2 4.9e-28 97.7 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY92733.1 - 1.4e-15 58.5 0.0 2.3e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY92733.1 - 1.1e-07 31.7 0.0 8.8e-07 28.8 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORY92733.1 - 5.6e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase CN_hydrolase PF00795.22 ORY92734.1 - 5.1e-16 58.8 0.0 2.6e-15 56.5 0.0 1.9 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Kinin PF08260.11 ORY92734.1 - 5.1 8.0 7.8 41 5.2 0.6 3.4 2 0 0 2 2 2 0 Insect kinin peptide Abhydrolase_1 PF00561.20 ORY92735.1 - 5.5e-20 72.1 0.0 4.7e-17 62.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY92735.1 - 3.8e-18 65.5 0.0 7.1e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Phage_holin_3_6 PF07332.11 ORY92736.1 - 0.98 9.5 8.7 1.5 8.8 8.7 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Asp_Glu_race PF01177.22 ORY92738.1 - 1e-07 32.0 0.1 1.8e-07 31.3 0.1 1.5 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Pkinase PF00069.25 ORY92739.1 - 1.4e-61 208.2 0.0 4.6e-44 150.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92739.1 - 8.8e-26 90.7 0.0 1.1e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY92739.1 - 5.5e-07 29.8 0.2 7.3e-06 26.1 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY92739.1 - 0.00083 18.8 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 ORY92739.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 ORY92739.1 - 0.0047 15.9 0.0 0.019 13.9 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 ORY92739.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY92739.1 - 0.26 10.0 0.0 0.44 9.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Zn_clus PF00172.18 ORY92740.1 - 5.1e-05 23.3 12.1 0.0001 22.3 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC53 PF10152.9 ORY92744.1 - 0.081 13.3 0.4 0.12 12.8 0.4 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SH3-RhoG_link PF16609.5 ORY92744.1 - 0.27 10.9 4.2 0.46 10.2 4.2 1.4 1 1 0 1 1 1 0 SH3-RhoGEF linking unstructured region DUF4680 PF15730.5 ORY92744.1 - 0.71 10.2 4.0 1.1 9.6 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Tti2 PF10521.9 ORY92745.1 - 2.3e-19 70.0 0.0 3.2e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Tti2 family XPG_I PF00867.18 ORY92746.1 - 1.5e-24 86.1 0.0 2.6e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY92746.1 - 3.3e-24 85.3 0.0 6.3e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 ORY92746.1 - 0.00026 20.5 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 ORY92746.1 - 0.0044 17.6 0.0 0.0081 16.7 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 ORY92746.1 - 0.023 14.5 0.0 0.62 10.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat HHH_5 PF14520.6 ORY92746.1 - 0.048 14.3 0.0 0.26 11.9 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain HemY_N PF07219.13 ORY92746.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 HemY protein N-terminus Tannase PF07519.11 ORY92746.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase HHH_2 PF12826.7 ORY92746.1 - 0.18 11.9 0.0 0.83 9.8 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Rcd1 PF04078.13 ORY92747.1 - 4.5e-124 412.9 1.3 5.5e-124 412.6 1.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Sec23_trunk PF04811.15 ORY92748.1 - 7.1e-74 248.4 0.0 1.1e-73 247.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORY92748.1 - 5.3e-30 104.0 0.0 9.5e-30 103.2 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORY92748.1 - 3.5e-26 91.0 0.2 6.7e-26 90.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ORY92748.1 - 2.1e-17 62.9 6.1 4.2e-17 61.9 6.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY92748.1 - 1.2e-10 41.1 0.0 1.2e-10 41.1 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat COesterase PF00135.28 ORY92750.1 - 1.7e-72 245.0 0.0 2.1e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY92750.1 - 3.4e-06 27.1 0.1 0.00016 21.6 0.1 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold PIG-S PF10510.9 ORY92751.1 - 7.2e-114 381.4 2.5 2.5e-104 350.0 0.1 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Snf7 PF03357.21 ORY92752.1 - 2.1e-34 118.6 17.4 2.7e-34 118.2 17.4 1.1 1 0 0 1 1 1 1 Snf7 APG6_N PF17675.1 ORY92752.1 - 0.0036 17.8 7.4 0.0036 17.8 7.4 2.3 2 0 0 2 2 2 1 Apg6 coiled-coil region Eno-Rase_FAD_bd PF07055.12 ORY92752.1 - 0.074 13.5 2.4 0.18 12.3 0.9 2.2 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain DUF3584 PF12128.8 ORY92752.1 - 0.11 10.0 12.6 0.14 9.7 12.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PhoU PF01895.19 ORY92752.1 - 0.28 11.7 5.3 2.6 8.6 0.3 2.9 2 1 0 2 2 2 0 PhoU domain T3SS_needle_E PF08988.10 ORY92752.1 - 0.57 10.4 4.2 7 6.9 0.4 3.1 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Fzo_mitofusin PF04799.13 ORY92752.1 - 1.3 8.5 11.1 0.88 9.1 3.7 2.9 1 1 3 4 4 4 0 fzo-like conserved region E2F_CC-MB PF16421.5 ORY92752.1 - 2.4 8.6 8.1 0.54 10.7 2.3 2.4 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain CENP-Q PF13094.6 ORY92752.1 - 2.7 8.2 19.0 0.35 11.1 13.7 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit 7TMR-HDED PF07697.11 ORY92752.1 - 3.4 7.7 11.9 1.4 9.0 5.1 2.1 1 1 1 2 2 2 0 7TM-HD extracellular DUF4407 PF14362.6 ORY92752.1 - 3.7 6.8 11.7 9.9 5.4 10.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) YlqD PF11068.8 ORY92752.1 - 5.1 7.5 16.7 2.4 8.5 12.8 2.1 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 ORY92752.1 - 6.5 6.2 13.9 11 5.4 13.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit FapA PF03961.13 ORY92752.1 - 8 4.9 13.5 2.9 6.4 8.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Ribo_biogen_C PF04034.13 ORY92753.1 - 1.5e-52 176.6 0.0 2.1e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 ORY92753.1 - 3.9e-15 55.4 0.1 6e-15 54.8 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI NMO PF03060.15 ORY92754.1 - 2.2e-31 109.5 8.0 4.7e-30 105.1 8.0 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY92754.1 - 2.1e-08 33.6 0.8 0.0022 17.0 0.0 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY92754.1 - 0.0024 16.9 1.6 0.0024 16.9 1.6 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY92754.1 - 0.015 14.5 0.2 0.023 13.8 0.2 1.3 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF1729 PF08354.10 ORY92754.1 - 0.071 12.0 1.1 0.25 10.2 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1729) DUF3584 PF12128.8 ORY92756.1 - 0.017 12.7 15.4 0.02 12.5 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc24 PF08286.11 ORY92756.1 - 0.03 14.6 0.1 0.03 14.6 0.1 3.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 ORY92756.1 - 5.5 7.5 21.3 1.3 9.6 8.6 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Kinesin PF00225.23 ORY92757.1 - 1.5e-87 293.6 0.4 2.4e-87 293.0 0.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY92757.1 - 3e-19 69.4 0.0 5.9e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_5 PF14520.6 ORY92757.1 - 0.0063 17.1 0.3 0.018 15.7 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_3 PF12836.7 ORY92757.1 - 0.0079 16.4 0.0 0.025 14.8 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 ORY92757.1 - 0.0095 15.8 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Trypan_PARP PF05887.11 ORY92757.1 - 0.76 9.7 5.8 0.26 11.3 2.6 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) HSP70 PF00012.20 ORY92759.1 - 1.4e-262 872.2 13.9 1.6e-262 872.1 13.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY92759.1 - 5.8e-14 51.7 2.8 4.1e-12 45.6 1.3 2.5 2 0 0 2 2 2 2 MreB/Mbl protein CPSase_L_D3 PF02787.19 ORY92759.1 - 0.14 12.5 1.4 0.43 10.9 1.4 1.9 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain BOP1NT PF08145.12 ORY92759.1 - 0.36 10.7 3.9 0.66 9.9 3.9 1.3 1 0 0 1 1 1 0 BOP1NT (NUC169) domain FtsA PF14450.6 ORY92759.1 - 0.38 11.2 11.8 1.6 9.2 0.1 4.0 3 2 0 3 3 3 0 Cell division protein FtsA Aldo_ket_red PF00248.21 ORY92761.1 - 3e-74 249.9 0.0 3.4e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Transp_cyt_pur PF02133.15 ORY92762.1 - 1.4e-87 294.3 30.2 1.6e-87 294.1 30.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Polysacc_deac_1 PF01522.21 ORY92763.1 - 0.00084 19.2 0.0 0.0021 18.0 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase Amidase PF01425.21 ORY92764.1 - 1.6e-93 314.1 0.0 2e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Amidase LRR_6 PF13516.6 ORY92765.1 - 4.4e-05 23.2 11.1 0.055 13.6 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 ORY92765.1 - 0.0035 17.7 13.1 0.013 15.9 1.2 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) X PF00739.19 ORY92765.1 - 0.12 12.5 0.9 0.33 11.1 0.9 1.7 1 0 0 1 1 1 0 Trans-activation protein X LRR_1 PF00560.33 ORY92765.1 - 0.2 12.3 10.9 2.6 8.9 0.2 5.0 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY92765.1 - 0.22 11.3 7.7 0.55 10.0 0.2 3.8 3 1 0 3 3 3 0 Leucine rich repeat Peptidase_M17 PF00883.21 ORY92766.1 - 3.6e-117 391.1 0.2 4.9e-117 390.6 0.2 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ORY92766.1 - 0.00023 21.0 2.1 0.00044 20.1 1.3 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain PDZ_2 PF13180.6 ORY92766.1 - 0.0082 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain TPT PF03151.16 ORY92767.1 - 1.7e-41 142.4 14.6 2.2e-41 142.1 14.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY92767.1 - 2.3e-10 40.2 17.3 5.4e-10 39.0 17.3 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY92767.1 - 8.3e-09 35.7 27.7 8.1e-05 22.8 9.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 ORY92767.1 - 0.27 10.4 8.5 2.1 7.4 1.2 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter TMEM234 PF10639.9 ORY92767.1 - 1.6 8.8 10.0 2.6 8.1 1.4 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 Sec23_trunk PF04811.15 ORY92768.1 - 3.5e-74 249.4 0.0 5.4e-74 248.8 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORY92768.1 - 5e-30 104.1 0.0 9.3e-30 103.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORY92768.1 - 3.5e-26 91.0 0.2 6.6e-26 90.1 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 ORY92768.1 - 2.1e-17 62.9 6.1 4.1e-17 61.9 6.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY92768.1 - 1.2e-10 41.1 0.0 1.2e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat CAP_GLY PF01302.25 ORY92768.1 - 0.069 13.2 0.0 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 CAP-Gly domain DUF2612 PF11041.8 ORY92768.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2612) MRP-L27 PF09809.9 ORY92769.1 - 3e-11 43.1 0.1 5.9e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 UNC-93 PF05978.16 ORY92770.1 - 9e-15 54.7 4.4 9e-15 54.7 4.4 2.3 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 ORY92770.1 - 6.9e-09 35.1 17.4 1.6e-05 24.0 7.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY92770.1 - 7e-08 31.8 33.0 7e-08 31.8 33.0 2.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Zip PF02535.22 ORY92770.1 - 0.19 10.9 1.9 0.38 9.9 1.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter AA_permease PF00324.21 ORY92771.1 - 2.4e-140 468.3 36.3 3e-140 468.0 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY92771.1 - 4.4e-40 137.8 39.5 5.7e-40 137.4 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2156 PF09924.9 ORY92772.1 - 5.3e-17 61.8 0.0 6.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Acetyltransf_6 PF13480.7 ORY92772.1 - 0.0056 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PWI PF01480.17 ORY92773.1 - 6e-27 93.8 0.0 9.1e-27 93.2 0.0 1.3 1 0 0 1 1 1 1 PWI domain zf-C2H2 PF00096.26 ORY92775.1 - 1.4e-07 31.6 11.7 0.00044 20.6 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY92775.1 - 0.00044 20.4 0.1 0.0039 17.4 0.5 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY92775.1 - 0.0026 18.1 0.4 0.0098 16.3 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY92775.1 - 0.0028 18.0 1.6 0.0028 18.0 1.6 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY92775.1 - 0.0028 17.6 0.8 0.0081 16.1 0.8 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY92775.1 - 0.0057 17.4 12.7 0.22 12.4 0.6 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger EMP24_GP25L PF01105.24 ORY92777.1 - 6.6e-39 133.7 0.0 7.5e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Trimer_CC PF08954.11 ORY92777.1 - 0.0062 16.1 0.1 0.032 13.8 0.0 2.0 2 0 0 2 2 2 1 Trimerisation motif TRPM_tetra PF16519.5 ORY92777.1 - 0.017 15.2 0.2 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DNApol_Exo PF18136.1 ORY92778.1 - 5.2e-94 314.5 0.0 8.6e-94 313.8 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 ORY92778.1 - 3.6e-47 161.2 0.0 5.8e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 ORY92778.1 - 0.041 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease Glyco_trans_2_3 PF13632.6 ORY92779.1 - 3.5e-43 147.8 0.8 3.5e-43 147.8 0.8 3.2 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY92779.1 - 0.00018 21.4 0.0 0.013 15.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY92779.1 - 0.0058 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.21 ORY92780.1 - 7.3e-11 41.8 0.1 1.4e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Carmo_coat_C PF08462.10 ORY92780.1 - 0.024 14.8 0.2 0.046 13.8 0.2 1.4 1 0 0 1 1 1 0 Carmovirus coat protein PIG-P PF08510.12 ORY92781.1 - 7.8e-33 113.0 1.7 9.3e-33 112.7 1.7 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 ORY92781.1 - 2.2 8.6 9.1 8.8 6.7 1.1 2.3 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Amino_oxidase PF01593.24 ORY92782.1 - 2.2e-14 53.6 0.5 6.1e-14 52.2 0.5 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY92782.1 - 2.2e-07 31.0 0.0 2.2e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY92782.1 - 2.5e-05 24.0 5.4 0.0048 16.5 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY92782.1 - 0.007 15.7 2.1 0.21 10.8 3.6 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Ish1 PF10281.9 ORY92782.1 - 0.013 15.8 0.0 2.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein MCRA PF06100.11 ORY92782.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 MCRA family Pyr_redox_2 PF07992.14 ORY92782.1 - 0.02 14.1 1.1 4.5 6.4 0.0 2.7 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY92782.1 - 0.054 13.5 2.7 0.054 13.5 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 ORY92782.1 - 1.7 9.3 5.1 20 5.8 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-C2H2 PF00096.26 ORY92783.1 - 0.16 12.4 0.1 0.41 11.2 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Neugrin PF06413.11 ORY92784.1 - 7.9e-10 39.1 0.1 9.1e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 ORY92784.1 - 2.3e-06 27.9 0.0 2.4e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 MarR_2 PF12802.7 ORY92784.1 - 0.00099 19.0 0.1 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 MarR family HTH_23 PF13384.6 ORY92784.1 - 0.0074 16.1 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_24 PF13412.6 ORY92784.1 - 0.0077 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_11 PF08279.12 ORY92784.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 HTH domain HTH_32 PF13565.6 ORY92784.1 - 0.038 14.6 0.2 0.044 14.4 0.2 1.1 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.16 ORY92784.1 - 0.072 12.6 0.5 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_DeoR PF08220.12 ORY92784.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_IclR PF09339.10 ORY92784.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_7 PF02796.15 ORY92784.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 ORY92784.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ORY92784.1 - 0.13 11.7 0.0 0.37 10.2 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Rrf2 PF02082.20 ORY92784.1 - 0.13 12.6 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator Pkinase PF00069.25 ORY92785.1 - 2.4e-73 246.7 0.0 2.7e-73 246.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92785.1 - 1.4e-31 109.7 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY92785.1 - 1.1e-05 24.9 0.0 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY92785.1 - 7.9e-05 21.8 0.0 0.00072 18.6 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY92785.1 - 0.0033 17.4 0.0 0.0098 15.8 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY92785.1 - 0.023 13.5 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 ORY92785.1 - 0.063 12.3 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 ORY92785.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Aldo_ket_red PF00248.21 ORY92787.1 - 5.5e-74 249.0 0.1 6.2e-74 248.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nrap_D5 PF17406.2 ORY92788.1 - 2e-44 151.2 1.8 3.6e-44 150.4 0.1 2.1 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 ORY92788.1 - 8.9e-39 133.1 0.0 1.8e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D4 PF17405.2 ORY92788.1 - 9.9e-26 90.4 0.1 8.3e-22 77.6 0.0 3.1 1 1 2 3 3 3 2 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 ORY92788.1 - 1.9e-23 82.9 0.0 1.5e-22 80.0 0.0 2.2 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 ORY92788.1 - 4.7e-22 78.7 0.0 1.7e-21 76.9 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 1 BLOC1S3 PF15753.5 ORY92788.1 - 0.00044 20.4 1.3 0.00086 19.5 1.3 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 Nrap_D6 PF17407.2 ORY92788.1 - 0.0064 16.7 0.0 0.017 15.3 0.0 1.7 2 0 0 2 2 1 1 Nrap protein domain 6 TMEM51 PF15345.6 ORY92788.1 - 0.048 13.5 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 SDA1 PF05285.12 ORY92788.1 - 0.055 12.9 18.3 0.089 12.2 18.3 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ORY92788.1 - 0.12 10.6 12.5 0.16 10.1 12.5 1.1 1 0 0 1 1 1 0 Nop14-like family Inhibitor_I53 PF11714.8 ORY92788.1 - 0.27 11.5 3.4 0.98 9.7 3.4 2.0 1 0 0 1 1 1 0 Thrombin inhibitor Madanin BUD22 PF09073.10 ORY92788.1 - 2.2 7.5 23.3 3.5 6.9 23.3 1.2 1 0 0 1 1 1 0 BUD22 DUF2461 PF09365.10 ORY92789.1 - 1.3e-68 231.1 0.1 1.7e-68 230.7 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) LktC PF06261.11 ORY92789.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC Acyl-CoA_dh_1 PF00441.24 ORY92790.1 - 3.9e-38 131.0 0.1 5.7e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY92790.1 - 3.5e-21 75.2 0.2 7.1e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY92790.1 - 4.6e-17 61.9 0.0 1.5e-16 60.3 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY92790.1 - 4.1e-16 59.6 0.0 1.2e-15 58.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY92790.1 - 3.8e-10 40.1 0.0 8.5e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40_4 PF16300.5 ORY92791.1 - 2.5e-27 94.5 1.1 4.9e-14 51.9 0.2 2.7 2 0 0 2 2 2 2 Type of WD40 repeat ANAPC4_WD40 PF12894.7 ORY92791.1 - 4.7e-12 46.0 0.0 0.0087 16.3 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 ORY92791.1 - 2.4e-09 36.9 0.0 0.00035 20.4 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF1899) WD40 PF00400.32 ORY92791.1 - 2.9e-07 31.1 10.4 0.056 14.3 0.5 6.6 6 1 0 6 6 6 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 ORY92791.1 - 0.005 15.9 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region Ge1_WD40 PF16529.5 ORY92791.1 - 0.0065 15.5 0.1 0.034 13.1 0.1 1.9 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SOG2 PF10428.9 ORY92791.1 - 5.7 6.0 21.7 0.46 9.6 15.9 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein Ribosomal_S19e PF01090.19 ORY92792.1 - 3.7e-57 191.8 0.0 4.3e-57 191.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ada3 PF10198.9 ORY92792.1 - 0.02 15.1 1.0 0.028 14.6 1.0 1.2 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Aldo_ket_red PF00248.21 ORY92793.1 - 6.3e-50 170.0 0.1 8e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family OSR1_C PF12202.8 ORY92793.1 - 0.18 12.1 0.8 0.38 11.0 0.8 1.5 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Histone_H2A_C PF16211.5 ORY92795.1 - 1.1e-18 66.6 0.9 2.2e-18 65.7 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY92795.1 - 1.5e-17 64.1 0.0 2e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92795.1 - 5.2e-05 23.4 0.0 9.5e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY92796.1 - 3.9e-21 75.8 1.4 4.7e-21 75.5 1.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92796.1 - 2.7e-05 24.4 0.0 6.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY92796.1 - 0.0032 17.9 0.0 0.0051 17.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 ORY92796.1 - 0.022 15.0 0.1 0.037 14.2 0.0 1.4 1 1 0 1 1 1 0 CENP-W protein DUF5539 PF17693.1 ORY92796.1 - 0.086 12.5 1.4 0.12 12.0 1.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Response_reg PF00072.24 ORY92797.1 - 6.9e-33 113.2 0.1 1.7e-23 82.9 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORY92797.1 - 8.6e-28 97.1 0.2 1.9e-27 96.0 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY92797.1 - 5.1e-17 61.7 0.1 2.3e-16 59.5 0.1 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 ORY92797.1 - 1.6e-11 44.9 0.3 1.6e-10 41.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 ORY92797.1 - 3e-10 40.5 0.2 1.1e-09 38.7 0.0 2.2 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.25 ORY92797.1 - 1.5e-08 34.3 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 ORY92797.1 - 3.6e-08 34.1 0.1 9.4e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ORY92797.1 - 1.2e-06 28.8 0.1 3.5e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.6 ORY92797.1 - 0.017 15.0 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinase-like PF14531.6 ORY92797.1 - 0.031 13.6 0.0 0.061 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like IFRD PF05004.13 ORY92798.1 - 0.18 10.9 0.1 0.23 10.5 0.1 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) MFS_1 PF07690.16 ORY92799.1 - 9.6e-24 83.9 71.0 7.6e-23 81.0 43.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY92800.1 - 3.1e-23 82.3 48.6 5.8e-21 74.8 40.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NCE101 PF11654.8 ORY92801.1 - 4.1e-22 77.6 0.2 5.5e-22 77.2 0.2 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 DUF1654 PF07867.11 ORY92801.1 - 0.013 15.2 0.4 0.021 14.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) 4HB_MCP_1 PF12729.7 ORY92801.1 - 0.082 12.5 0.1 0.099 12.2 0.1 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Sugar_tr PF00083.24 ORY92802.1 - 4.4e-85 286.2 22.0 5.2e-85 286.0 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY92802.1 - 4.5e-12 45.6 43.6 7.7e-08 31.6 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Spt20 PF12090.8 ORY92803.1 - 3.7e-36 124.9 0.1 1.4e-24 87.1 0.0 3.0 2 1 1 3 3 3 2 Spt20 family TFIIE_alpha PF02002.17 ORY92804.1 - 1.7e-17 63.1 0.8 3.6e-17 62.1 0.8 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TFIIE-A_C PF11521.8 ORY92804.1 - 0.00052 20.3 8.6 0.00052 20.3 8.6 2.8 2 1 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha HTH_Crp_2 PF13545.6 ORY92804.1 - 0.032 14.2 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain ADK_lid PF05191.14 ORY92804.1 - 0.065 13.2 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid DZR PF12773.7 ORY92804.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf_UBZ PF18439.1 ORY92804.1 - 0.18 11.5 0.9 0.83 9.3 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger CARD PF00619.21 ORY92804.1 - 0.24 11.4 1.4 2.9 8.0 0.2 2.4 2 0 0 2 2 2 0 Caspase recruitment domain zf-C2H2 PF00096.26 ORY92804.1 - 0.42 11.2 1.3 1.2 9.7 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type HAD PF12710.7 ORY92805.1 - 5.7e-24 85.6 0.0 7e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 ORY92805.1 - 9e-06 25.4 0.0 2.3e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 ORY92805.1 - 0.00011 22.6 0.9 0.054 13.8 0.0 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY92805.1 - 0.00045 20.4 0.2 0.0052 16.9 0.2 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ORY92805.1 - 0.00066 19.1 0.1 0.0018 17.7 0.0 1.6 2 0 0 2 2 2 1 Putative Phosphatase MBOAT PF03062.19 ORY92806.1 - 2.4e-32 112.7 10.5 2.4e-32 112.7 10.5 2.3 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY92806.1 - 0.0016 18.6 2.5 0.0039 17.4 2.5 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DHHC PF01529.20 ORY92807.1 - 7.1e-29 100.6 1.8 7.1e-29 100.6 1.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase SecY PF00344.20 ORY92807.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 SecY translocase ATG11 PF10377.9 ORY92808.1 - 3.5e-34 117.6 0.1 3.5e-34 117.6 0.1 3.1 3 0 0 3 3 3 1 Autophagy-related protein 11 BssS PF13991.6 ORY92808.1 - 0.034 14.2 0.5 0.66 10.1 0.1 2.7 2 0 0 2 2 2 0 BssS protein family Fib_alpha PF08702.10 ORY92808.1 - 0.24 11.6 6.3 1.1 9.4 1.1 3.7 3 2 0 3 3 3 0 Fibrinogen alpha/beta chain family Filament PF00038.21 ORY92808.1 - 4.6 6.7 42.7 1.7 8.2 2.0 3.7 2 1 1 3 3 3 0 Intermediate filament protein FlxA PF14282.6 ORY92809.1 - 0.12 12.4 1.3 0.59 10.2 1.3 2.2 1 0 0 1 1 1 0 FlxA-like protein Fungal_trans PF04082.18 ORY92810.1 - 3.9e-16 58.9 0.0 6.9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY92810.1 - 0.00042 20.4 5.7 0.00079 19.5 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAG PF02179.16 ORY92811.1 - 6.2e-07 29.8 3.1 9.5e-07 29.2 0.0 2.9 2 1 0 2 2 2 1 BAG domain Iron_traffic PF04362.14 ORY92811.1 - 0.13 12.0 3.8 0.27 10.9 3.8 1.5 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking FA_hydroxylase PF04116.13 ORY92812.1 - 1.2e-20 74.2 22.2 1.2e-20 74.2 22.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MAPEG PF01124.18 ORY92813.1 - 6.9e-15 55.1 6.1 8.4e-15 54.8 6.1 1.1 1 0 0 1 1 1 1 MAPEG family PIP5K PF01504.18 ORY92814.1 - 1.3e-96 323.1 0.0 1.9e-96 322.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_hydro_16 PF00722.21 ORY92815.1 - 1.7e-11 43.9 0.2 3.7e-11 42.8 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 ORY92816.1 - 7.2e-45 153.3 2.7 7.2e-45 153.3 2.7 2.8 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY92816.1 - 8e-05 22.5 0.0 0.022 14.6 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY92816.1 - 0.0028 17.6 0.1 0.072 13.0 0.0 2.8 2 1 1 3 3 3 1 Glycosyltransferase like family 2 DUF1996 PF09362.10 ORY92817.1 - 6.6e-69 232.5 0.0 1.3e-68 231.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 ORY92817.1 - 6.7e-34 115.9 52.7 4.2e-14 52.5 11.8 3.9 4 0 0 4 4 4 3 WSC domain Dicty_REP PF05086.12 ORY92817.1 - 0.028 12.4 0.3 0.036 12.1 0.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MSP1_C PF07462.11 ORY92817.1 - 0.57 8.8 4.6 0.93 8.1 4.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CPBP PF02517.16 ORY92818.1 - 2.3e-17 63.2 2.1 2.3e-17 63.2 2.1 2.3 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Acetyltransf_1 PF00583.25 ORY92819.1 - 1.7e-16 60.5 0.1 2.4e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY92819.1 - 1.8e-10 41.1 0.0 2.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY92819.1 - 9.9e-10 38.4 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY92819.1 - 2.1e-09 37.2 0.1 3.1e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY92819.1 - 8.4e-06 26.5 0.0 1e-05 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY92819.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY92819.1 - 9.3e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY92819.1 - 0.055 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.7 ORY92819.1 - 0.11 12.0 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Cytochrom_B558a PF05038.13 ORY92819.1 - 2.5 7.7 4.5 18 4.8 3.3 2.1 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Formyl_trans_N PF00551.19 ORY92820.1 - 8.8e-27 94.0 0.0 1.4e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 ORY92820.1 - 2.5e-11 43.7 0.0 4.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MIIP PF15734.5 ORY92820.1 - 0.055 13.0 0.4 0.099 12.1 0.4 1.3 1 0 0 1 1 1 0 Migration and invasion-inhibitory MNHE PF01899.16 ORY92820.1 - 0.2 11.4 0.1 0.49 10.1 0.0 1.6 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit RHH_1 PF01402.21 ORY92822.1 - 0.05 13.6 0.8 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family WD40 PF00400.32 ORY92824.1 - 2.5e-59 195.9 20.8 7.6e-11 42.4 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92824.1 - 3.5e-25 88.1 0.0 2e-07 31.2 0.0 6.2 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 ORY92824.1 - 4.3e-21 75.0 7.7 1.1e-20 73.7 7.7 1.6 1 1 0 1 1 1 1 Tup N-terminal Ge1_WD40 PF16529.5 ORY92824.1 - 6.1e-12 45.1 0.1 0.0047 15.9 0.0 5.8 1 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ORY92824.1 - 3.9e-10 39.4 0.7 1.5 8.9 0.0 6.3 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 ORY92824.1 - 7.2e-09 35.4 0.0 0.21 10.9 0.0 4.2 4 1 0 4 4 4 3 WD40-like domain Nup160 PF11715.8 ORY92824.1 - 2.4e-07 29.8 0.5 0.78 8.3 0.1 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY92824.1 - 7.4e-05 22.7 0.0 0.13 12.1 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 ORY92824.1 - 0.00035 19.2 0.0 0.042 12.4 0.0 2.3 1 1 0 2 2 2 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 ORY92824.1 - 0.00049 19.7 6.6 8 6.3 0.0 5.1 5 0 0 5 5 5 2 Proteasome subunit A N-terminal signature Nbas_N PF15492.6 ORY92824.1 - 0.00082 18.8 1.2 0.49 9.7 0.0 3.9 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DUF5122 PF17164.4 ORY92824.1 - 0.0046 17.2 4.3 77 3.7 0.0 5.6 6 0 0 6 6 6 0 Domain of unknown function (DUF5122) beta-propeller Frtz PF11768.8 ORY92824.1 - 0.014 13.7 0.0 0.82 7.9 0.0 2.7 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Spc7 PF08317.11 ORY92824.1 - 0.14 11.0 2.7 0.21 10.5 2.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.18 ORY92824.1 - 0.16 12.2 1.8 1.1 9.6 1.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper nos_propeller PF18764.1 ORY92824.1 - 0.17 11.8 0.0 61 3.6 0.0 3.7 4 0 0 4 4 3 0 Nitrous oxide reductase propeller repeat TSNAXIP1_N PF15739.5 ORY92824.1 - 0.23 11.8 3.0 0.4 11.1 3.0 1.3 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF3584 PF12128.8 ORY92824.1 - 0.41 8.1 4.1 0.55 7.7 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HalX PF08663.10 ORY92824.1 - 0.8 10.1 4.7 1.6 9.1 2.0 2.1 2 0 0 2 2 2 0 HalX domain Aa_trans PF01490.18 ORY92825.1 - 4.3e-28 98.2 27.0 6.8e-28 97.5 27.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pyridoxal_deC PF00282.19 ORY92826.1 - 1.6e-20 73.2 0.0 2.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY92826.1 - 4.1e-10 39.2 0.0 9e-10 38.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY92826.1 - 0.00035 20.0 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DAGK_cat PF00781.24 ORY92827.1 - 5.1e-24 84.3 0.0 7.2e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Sec23_trunk PF04811.15 ORY92828.1 - 4.2e-74 249.2 0.0 6.2e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY92828.1 - 2.6e-23 81.8 0.1 8.4e-23 80.2 0.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY92828.1 - 3.1e-18 66.3 0.0 9e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY92828.1 - 7.4e-16 57.9 6.0 1.3e-15 57.2 6.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY92828.1 - 2.4e-09 37.0 0.0 5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.26 ORY92828.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 WW domain Vps36-NZF-N PF16988.5 ORY92828.1 - 0.0031 16.9 0.8 0.0063 15.9 0.8 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sec62 PF03839.16 ORY92829.1 - 1.9e-55 187.7 0.8 7.5e-55 185.8 0.8 1.7 1 1 0 1 1 1 1 Translocation protein Sec62 DUF3413 PF11893.8 ORY92829.1 - 3 6.9 7.5 4.4 6.4 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Cnd1 PF12717.7 ORY92830.1 - 1.3e-56 191.1 5.8 5.6e-52 176.1 0.4 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 ORY92830.1 - 5.8e-52 175.9 3.1 2.6e-51 173.8 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 ORY92830.1 - 1.5e-05 24.8 0.3 2.4 8.6 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 ORY92830.1 - 0.00013 22.3 0.0 0.15 12.4 0.0 4.5 3 2 1 4 4 4 2 HEAT repeats ENTH PF01417.20 ORY92830.1 - 0.00028 20.9 0.5 0.26 11.4 0.0 3.5 3 0 0 3 3 3 1 ENTH domain Cnd3 PF12719.7 ORY92830.1 - 0.0038 16.5 2.5 0.008 15.4 0.6 2.4 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 ORY92830.1 - 0.0041 17.3 0.3 7.5 6.8 0.0 4.0 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 ORY92830.1 - 0.031 14.8 0.0 94 3.7 0.0 4.3 3 0 0 3 3 3 0 HEAT-like repeat BLYB PF05289.11 ORY92830.1 - 0.057 13.6 0.1 1.7 8.8 0.0 2.9 2 0 0 2 2 2 0 Borrelia hemolysin accessory protein PqqD PF05402.12 ORY92830.1 - 0.09 13.1 2.2 1.8 8.9 0.0 4.3 5 0 0 5 5 5 0 Coenzyme PQQ synthesis protein D (PqqD) ATG16 PF08614.11 ORY92831.1 - 0.00023 21.5 13.5 0.00023 21.5 13.5 10.4 4 2 4 9 9 9 2 Autophagy protein 16 (ATG16) Rootletin PF15035.6 ORY92831.1 - 0.0025 17.9 4.5 0.0025 17.9 4.5 7.2 2 2 4 7 7 7 3 Ciliary rootlet component, centrosome cohesion PACT_coil_coil PF10495.9 ORY92831.1 - 0.0038 17.8 0.0 0.03 14.9 0.0 2.7 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein UPF0242 PF06785.11 ORY92831.1 - 0.0061 16.7 8.2 0.0061 16.7 8.2 8.2 4 2 3 7 7 7 1 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 ORY92831.1 - 0.0069 16.2 0.6 0.0069 16.2 0.6 10.2 11 1 2 13 13 13 3 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 ORY92831.1 - 0.023 14.8 0.6 0.023 14.8 0.6 10.5 4 2 7 12 12 12 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 ORY92831.1 - 0.023 14.7 0.5 0.023 14.7 0.5 8.9 3 2 6 9 9 9 0 Laminin Domain II Filament PF00038.21 ORY92831.1 - 4.9 6.7 118.3 0.013 15.1 31.8 7.7 3 2 4 7 7 7 0 Intermediate filament protein Clr2_transil PF16761.5 ORY92832.1 - 3.8e-20 72.5 0.4 8.3e-20 71.4 0.4 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 ORY92832.1 - 3e-11 44.3 1.0 1.2e-10 42.3 0.0 2.7 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 zf-CCCH PF00642.24 ORY92833.1 - 5.1e-16 58.1 22.6 9e-09 35.0 1.3 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY92833.1 - 4.7e-10 39.2 25.4 0.00026 20.9 2.1 4.1 4 0 0 4 4 4 3 Zinc finger domain zf-CCCH_4 PF18044.1 ORY92833.1 - 0.0024 17.6 1.2 0.0024 17.6 1.2 3.9 5 0 0 5 5 5 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY92833.1 - 0.0032 17.9 19.9 0.094 13.2 0.9 3.3 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY92833.1 - 0.025 15.3 18.7 0.18 12.5 0.8 4.1 1 1 1 3 3 3 0 Torus domain BUD22 PF09073.10 ORY92833.1 - 0.53 9.6 24.0 1.3 8.3 24.0 1.7 1 0 0 1 1 1 0 BUD22 zf-CCCH_3 PF15663.5 ORY92833.1 - 0.76 10.0 18.1 1.8 8.8 4.9 3.2 1 1 2 3 3 3 0 Zinc-finger containing family SOG2 PF10428.9 ORY92833.1 - 8.7 5.4 18.0 13 4.8 18.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein ADH_zinc_N PF00107.26 ORY92834.1 - 2.3e-18 66.4 0.0 4.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY92834.1 - 2.1e-05 25.6 0.0 4.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY92834.1 - 0.00053 19.9 0.2 0.0013 18.6 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain S-AdoMet_synt_C PF02773.16 ORY92835.1 - 1.2e-66 222.9 0.5 2.4e-66 221.9 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORY92835.1 - 1.6e-46 157.5 0.0 2.9e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORY92835.1 - 1.2e-44 151.0 0.1 2.5e-44 150.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORY92835.1 - 0.0073 15.1 0.1 0.098 11.4 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase (AdoMet synthetase) tRNA-synt_1 PF00133.22 ORY92836.1 - 9.2e-36 123.3 0.0 6e-15 54.5 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ORY92836.1 - 2.5e-15 56.1 0.0 3.9e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORY92836.1 - 1.4e-11 44.6 0.0 3.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORY92836.1 - 1e-08 34.9 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain F-box-like PF12937.7 ORY92837.1 - 1.7e-06 27.8 0.6 4.7e-06 26.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like TPR_2 PF07719.17 ORY92837.1 - 2.9e-05 23.8 2.8 0.19 11.9 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY92837.1 - 0.00016 21.3 0.1 2.3 8.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat LRR_4 PF12799.7 ORY92837.1 - 0.0025 18.2 0.4 35 5.0 0.0 5.1 4 1 2 6 6 6 0 Leucine Rich repeats (2 copies) TPR_11 PF13414.6 ORY92837.1 - 0.0063 16.2 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_12 PF13424.6 ORY92837.1 - 0.0077 16.5 1.4 0.12 12.7 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY92837.1 - 0.01 16.6 5.9 2.9 8.9 0.1 4.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY92837.1 - 0.074 13.7 5.9 0.05 14.3 3.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY92837.1 - 0.16 12.0 0.6 2.3 8.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Arrestin_N PF00339.29 ORY92838.1 - 1.5e-05 25.1 0.0 0.00021 21.4 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 ORY92839.1 - 5e-06 26.6 0.0 8.4e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ADC PF06314.11 ORY92840.1 - 0.00026 20.6 0.0 0.00042 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Nucleoporin_N PF08801.11 ORY92840.1 - 0.21 10.3 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Sel_put PF04328.13 ORY92841.1 - 0.00028 20.9 0.2 0.00055 19.9 0.0 1.6 2 0 0 2 2 2 1 Selenoprotein, putative zf-met2 PF12907.7 ORY92841.1 - 0.0062 16.7 3.1 0.017 15.3 3.1 1.8 1 1 0 1 1 1 1 Zinc-binding HECT_2 PF09814.9 ORY92841.1 - 0.033 13.1 0.2 0.033 13.1 0.2 1.0 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding 4F5 PF04419.14 ORY92841.1 - 0.033 15.1 11.2 0.06 14.2 11.2 1.4 1 0 0 1 1 1 0 4F5 protein family Eapp_C PF10238.9 ORY92841.1 - 0.064 13.3 0.5 0.073 13.2 0.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein zf-BED PF02892.15 ORY92841.1 - 0.085 12.9 0.6 0.16 12.0 0.6 1.5 1 1 0 1 1 1 0 BED zinc finger Beta-lactamase PF00144.24 ORY92842.1 - 2.6e-26 92.7 0.2 1.2e-25 90.5 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase Histone PF00125.24 ORY92843.1 - 3.9e-21 75.8 1.4 4.7e-21 75.5 1.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92843.1 - 2.7e-05 24.4 0.0 6.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY92843.1 - 0.0032 17.9 0.0 0.0051 17.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 ORY92843.1 - 0.022 15.0 0.1 0.037 14.2 0.0 1.4 1 1 0 1 1 1 0 CENP-W protein DUF5539 PF17693.1 ORY92843.1 - 0.086 12.5 1.4 0.12 12.0 1.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Histone_H2A_C PF16211.5 ORY92844.1 - 1.3e-18 66.4 0.9 2.6e-18 65.4 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY92844.1 - 1.4e-12 48.1 0.0 2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY92844.1 - 0.0064 16.7 0.0 0.0097 16.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Beta-lactamase PF00144.24 ORY92845.1 - 2.4e-28 99.4 3.0 8.7e-28 97.5 3.0 1.9 1 1 0 1 1 1 1 Beta-lactamase ABC_membrane PF00664.23 ORY92846.1 - 4.4e-107 357.8 33.8 6.9e-55 186.6 16.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY92846.1 - 1.7e-66 222.9 0.0 7.9e-34 117.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY92846.1 - 8e-15 54.9 1.8 0.00037 20.0 0.1 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY92846.1 - 4.3e-08 32.4 2.8 0.0074 15.1 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 ORY92846.1 - 1.2e-07 31.3 2.3 0.0057 16.4 0.4 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY92846.1 - 8.8e-07 29.0 0.0 0.036 13.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY92846.1 - 9.2e-07 28.9 0.0 0.045 13.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY92846.1 - 1.3e-06 28.7 4.3 0.0027 18.0 0.0 4.2 3 2 0 3 3 3 2 AAA domain AAA_23 PF13476.6 ORY92846.1 - 1.7e-06 28.7 0.7 0.13 12.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY92846.1 - 9.7e-06 26.1 3.6 0.013 15.9 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 ORY92846.1 - 5.4e-05 23.1 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ORY92846.1 - 0.0002 20.7 0.1 0.79 9.0 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin AAA_30 PF13604.6 ORY92846.1 - 0.00022 21.0 5.4 0.43 10.3 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY92846.1 - 0.00023 20.8 0.1 1.7 8.1 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA PF00004.29 ORY92846.1 - 0.00026 21.4 1.1 0.14 12.6 0.1 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORY92846.1 - 0.0021 18.3 0.3 1.2 9.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY92846.1 - 0.0023 18.5 0.4 0.69 10.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 ORY92846.1 - 0.0041 17.0 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 ORY92846.1 - 0.0063 16.0 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 ORY92846.1 - 0.0065 16.6 0.1 0.85 9.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ORY92846.1 - 0.0071 16.6 3.9 1.7 8.9 0.4 3.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 ORY92846.1 - 0.0072 16.3 0.2 1.6 8.8 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) PRK PF00485.18 ORY92846.1 - 0.014 15.2 0.1 0.4 10.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 ORY92846.1 - 0.016 15.3 0.3 1.8 8.7 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 ORY92846.1 - 0.021 14.0 0.5 0.36 10.0 0.0 2.5 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 ORY92846.1 - 0.027 14.2 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY92846.1 - 0.028 14.8 0.1 1.8 9.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.6 ORY92846.1 - 0.031 14.3 0.0 0.56 10.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 ORY92846.1 - 0.046 12.9 0.1 9.2 5.3 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 ORY92846.1 - 0.059 13.5 0.5 12 5.9 0.0 2.9 2 1 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 ORY92846.1 - 0.098 12.4 0.3 16 5.2 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 ORY92846.1 - 0.12 12.1 0.5 5.2 6.8 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_17 PF13207.6 ORY92846.1 - 0.38 11.2 2.4 27 5.2 0.0 3.5 4 0 0 4 4 2 0 AAA domain Fungal_trans_2 PF11951.8 ORY92847.1 - 4.3e-14 52.1 0.0 3.1e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY92847.1 - 0.00043 20.3 6.1 0.00077 19.5 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.23 ORY92848.1 - 2.1e-06 27.5 0.0 2.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY92848.1 - 3.6e-06 26.8 0.0 5.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORY92848.1 - 0.017 15.2 0.0 0.28 11.3 0.0 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase MMR_HSR1_Xtn PF16897.5 ORY92849.1 - 2.4e-39 133.6 0.3 9.6e-39 131.7 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 ORY92849.1 - 2.9e-23 81.7 0.2 5.4e-23 80.8 0.2 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 ORY92849.1 - 2.2e-19 69.6 0.1 4.1e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY92849.1 - 4.6e-08 32.7 0.2 2.8e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY92849.1 - 0.11 12.6 0.5 5.1 7.1 0.0 2.3 1 1 1 2 2 2 0 Dynamin family Coatomer_WDAD PF04053.14 ORY92850.1 - 2.2e-143 478.5 0.0 5.4e-143 477.2 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 ORY92850.1 - 1.6e-126 422.4 0.0 2e-126 422.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 ORY92850.1 - 2.9e-41 138.7 15.9 1e-08 35.6 0.7 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92850.1 - 1.8e-09 37.8 0.7 0.01 16.1 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY92850.1 - 0.0012 17.6 5.8 0.42 9.2 0.0 4.6 2 1 3 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY92850.1 - 0.017 13.9 0.8 6.8 5.3 0.0 3.5 2 1 2 4 4 4 0 Nup133 N terminal like Asp_protease_2 PF13650.6 ORY92851.1 - 0.00023 21.7 0.0 0.00049 20.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 ORY92851.1 - 0.0003 21.3 0.0 0.00089 19.8 0.0 1.9 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 ORY92851.1 - 0.003 17.9 0.4 0.0062 16.8 0.0 1.8 2 0 0 2 2 2 1 Retroviral aspartyl protease Peptidase_A3 PF02160.15 ORY92851.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Fungal_trans_2 PF11951.8 ORY92852.1 - 1.6e-17 63.4 0.0 2.2e-16 59.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY92852.1 - 0.0015 18.6 7.9 0.0015 18.6 7.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rhodanese PF00581.20 ORY92853.1 - 7e-08 33.0 0.0 9.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rad52_Rad22 PF04098.15 ORY92854.1 - 1.3e-54 184.3 0.2 1.5e-54 184.1 0.2 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein SNF2_N PF00176.23 ORY92855.1 - 6.9e-59 199.3 0.0 1.1e-58 198.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 ORY92855.1 - 6.5e-35 120.9 7.2 2.3e-34 119.1 7.2 1.8 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 ORY92855.1 - 3.4e-17 62.8 0.0 8.4e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY92855.1 - 2.6e-09 37.3 0.0 1.1e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY92855.1 - 7.7e-05 22.0 0.0 0.00027 20.2 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 ORY92855.1 - 0.0013 18.0 0.4 0.0077 15.4 0.0 2.3 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 ORY92855.1 - 0.0071 16.0 0.0 0.027 14.2 0.0 2.1 3 0 0 3 3 3 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 ORY92855.1 - 0.025 14.8 0.2 0.42 10.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain Amidohydro_1 PF01979.20 ORY92856.1 - 3.9e-32 111.9 0.0 4.7e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY92856.1 - 1.1e-12 48.2 0.1 6.3e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Zw10 PF06248.13 ORY92857.1 - 3.4e-08 32.5 0.0 3.4e-05 22.6 0.0 2.5 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 ORY92857.1 - 0.0084 15.8 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Glyco_transf_24 PF18404.1 ORY92858.1 - 5.3e-145 481.8 1.7 7.7e-145 481.3 1.7 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 ORY92858.1 - 4.4e-62 210.3 0.0 3.7e-61 207.3 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 ORY92858.1 - 1.1e-32 113.8 0.0 4.9e-31 108.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 ORY92858.1 - 7.3e-32 109.7 0.0 1.3e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 ORY92858.1 - 9.5e-29 100.0 0.0 4.4e-28 97.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 ORY92858.1 - 8.3e-05 22.3 0.4 0.00015 21.5 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 SDH_alpha PF03313.15 ORY92859.1 - 2.9e-100 335.2 0.1 3.7e-100 334.9 0.1 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ORY92859.1 - 3.8e-58 196.2 0.1 8.3e-58 195.2 0.0 1.6 2 0 0 2 2 2 1 Serine dehydratase beta chain Vps16_C PF04840.12 ORY92860.1 - 2e-85 286.7 0.0 2.8e-85 286.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 ORY92860.1 - 7.5e-83 278.6 0.0 1e-82 278.1 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region LSM PF01423.22 ORY92861.1 - 3.4e-19 68.3 0.3 4.4e-19 67.9 0.3 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 ORY92861.1 - 0.12 12.5 0.3 0.27 11.4 0.1 1.6 1 1 1 2 2 2 0 RimP C-terminal SH3 domain UDPG_MGDP_dh_N PF03721.14 ORY92862.1 - 0.0026 17.4 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY92863.1 - 1.6e-48 164.8 0.0 2.4e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 ORY92863.1 - 5e-32 110.4 0.0 4.7e-30 104.1 0.0 3.2 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 ORY92863.1 - 9.6e-31 105.9 0.0 1.7e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Abhydrolase_6 PF12697.7 ORY92865.1 - 1.1e-15 58.8 2.6 1.3e-15 58.6 2.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY92865.1 - 1.2e-11 44.7 0.0 1.6e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY92865.1 - 1.1e-09 37.9 0.5 3.4e-09 36.3 0.1 2.0 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORY92865.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Isochorismatase PF00857.20 ORY92866.1 - 5.4e-29 101.6 0.1 6.3e-29 101.4 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Acetyltransf_2 PF00797.17 ORY92867.1 - 2.1e-34 119.4 0.0 3.2e-32 112.3 0.0 3.1 1 1 0 1 1 1 1 N-acetyltransferase Sdh5 PF03937.16 ORY92869.1 - 1.1e-14 54.2 0.3 2e-14 53.3 0.3 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase HSCB_C PF07743.13 ORY92870.1 - 1.2e-17 64.1 3.8 2e-17 63.4 3.8 1.3 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 ORY92870.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DZR PF12773.7 ORY92870.1 - 0.055 13.5 1.5 0.1 12.6 1.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY92870.1 - 0.25 11.1 1.1 0.44 10.3 1.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain CCDC-167 PF15188.6 ORY92870.1 - 0.29 11.5 1.9 0.5 10.7 1.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Zn_Tnp_IS1 PF03811.13 ORY92870.1 - 3.2 7.6 7.6 2.6 7.9 1.0 2.3 2 0 0 2 2 2 0 InsA N-terminal domain Fungal_trans_2 PF11951.8 ORY92871.1 - 1.9e-16 59.9 0.1 2.3e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Complex1_30kDa PF00329.19 ORY92871.1 - 0.088 13.4 0.1 1.8 9.2 0.0 2.2 1 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Zn_clus PF00172.18 ORY92872.1 - 0.00041 20.4 8.1 0.00066 19.7 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain gag-asp_proteas PF13975.6 ORY92873.1 - 8.1e-06 26.3 0.2 3.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY92873.1 - 3.5e-05 24.4 0.3 0.00014 22.4 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.12 ORY92873.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.7 2 0 0 2 2 2 0 Putative peptidase (DUF1758) Nucleos_tra2_N PF01773.20 ORY92873.1 - 0.079 13.6 0.2 0.24 12.0 0.2 1.8 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus RVP PF00077.20 ORY92873.1 - 0.16 12.3 0.2 0.59 10.5 0.1 1.8 1 1 1 2 2 2 0 Retroviral aspartyl protease DUF4171 PF13775.6 ORY92873.1 - 2.2 8.7 19.6 1.8 9.0 12.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4171) ADH_zinc_N_2 PF13602.6 ORY92874.1 - 9.9e-27 94.6 0.0 1.5e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY92874.1 - 5.3e-18 65.2 0.0 8.3e-18 64.6 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 ORY92874.1 - 0.028 14.2 0.1 0.049 13.3 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 ORY92875.1 - 5.8e-14 53.3 0.0 5.9e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF630 PF04783.12 ORY92875.1 - 0.04 14.1 0.1 0.085 13.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF630) Lig_C PF18330.1 ORY92875.1 - 0.093 12.7 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF1771 PF08590.10 ORY92875.1 - 0.1 13.0 2.0 1.1 9.7 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) ubiquitin PF00240.23 ORY92876.1 - 9.1e-09 34.9 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family NDUFA12 PF05071.16 ORY92877.1 - 5.6e-09 36.7 0.5 1.1e-08 35.8 0.1 1.6 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF4407 PF14362.6 ORY92877.1 - 0.017 14.5 3.9 0.02 14.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hs1pro-1_C PF07014.12 ORY92877.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus ABC_membrane PF00664.23 ORY92878.1 - 1.3e-104 349.7 29.9 7.3e-55 186.5 15.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY92878.1 - 2.4e-56 190.0 0.0 1.2e-29 103.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY92878.1 - 7e-13 48.5 0.8 0.0012 18.3 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY92878.1 - 7.9e-08 31.9 2.0 0.0054 16.4 0.4 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY92878.1 - 3.2e-07 30.4 0.0 0.025 14.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY92878.1 - 9.5e-07 29.2 2.6 0.004 17.4 0.0 4.0 3 2 0 3 3 3 2 AAA domain AAA_23 PF13476.6 ORY92878.1 - 2.3e-06 28.3 0.3 0.12 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 ORY92878.1 - 3.9e-06 26.9 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY92878.1 - 5e-05 23.8 6.7 0.012 16.0 0.1 3.5 3 2 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 ORY92878.1 - 5.7e-05 23.0 0.0 0.3 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 ORY92878.1 - 0.00012 21.7 0.1 1.3 8.6 0.0 3.7 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 ORY92878.1 - 0.00019 20.8 0.8 0.84 8.9 0.0 3.3 4 0 0 4 4 4 2 Zeta toxin AAA_30 PF13604.6 ORY92878.1 - 0.0004 20.2 6.6 0.59 9.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 ORY92878.1 - 0.00065 19.3 0.0 0.63 9.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_ATPase PF09818.9 ORY92878.1 - 0.00097 18.0 1.0 0.11 11.3 0.1 3.4 4 0 0 4 4 3 1 Predicted ATPase of the ABC class AAA_28 PF13521.6 ORY92878.1 - 0.0021 18.3 1.1 1.6 9.0 0.0 3.6 4 0 0 4 4 2 1 AAA domain AAA_18 PF13238.6 ORY92878.1 - 0.0031 18.1 0.1 1.4 9.5 0.0 3.0 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 ORY92878.1 - 0.0036 17.2 0.0 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_33 PF13671.6 ORY92878.1 - 0.0048 17.0 0.1 0.65 10.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY92878.1 - 0.007 16.4 0.1 1.1 9.2 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY92878.1 - 0.008 16.6 2.7 2.3 8.6 0.1 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ORY92878.1 - 0.013 15.6 0.5 1.5 9.0 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.22 ORY92878.1 - 0.018 14.2 0.5 0.27 10.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.6 ORY92878.1 - 0.023 14.7 0.1 0.48 10.5 0.0 3.0 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 ORY92878.1 - 0.031 14.4 0.6 9.6 6.2 0.0 3.1 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_24 PF13479.6 ORY92878.1 - 0.037 13.7 0.0 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORY92878.1 - 0.042 13.6 0.1 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 ORY92878.1 - 0.042 14.2 0.2 1.9 8.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase G-alpha PF00503.20 ORY92878.1 - 0.066 12.4 0.1 8.7 5.4 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 ORY92878.1 - 0.092 12.5 0.3 15 5.3 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 ORY92878.1 - 0.17 12.3 2.2 25 5.3 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.6 ORY92878.1 - 0.19 12.0 0.9 19 5.6 0.1 3.1 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 ORY92878.1 - 0.23 11.7 5.4 18 5.7 0.2 3.8 2 2 1 3 3 3 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 ORY92878.1 - 0.23 11.4 0.9 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF4191 PF13829.6 ORY92878.1 - 7.4 5.8 11.2 4 6.7 2.9 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Asp_protease_2 PF13650.6 ORY92879.1 - 0.064 13.9 0.0 0.78 10.4 0.0 2.6 2 1 1 3 3 3 0 Aspartyl protease tRNA-synt_2b PF00587.25 ORY92880.1 - 1.4e-17 64.2 0.0 2.5e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY92880.1 - 3e-17 62.5 0.0 6.7e-17 61.4 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.11 ORY92880.1 - 4e-08 33.3 0.8 8.1e-08 32.4 0.8 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal RNA_pol_N PF01194.17 ORY92881.1 - 1.9e-31 108.2 0.3 2.1e-31 108.0 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit CUE PF02845.16 ORY92884.1 - 0.017 14.8 0.3 0.06 13.1 0.1 2.0 2 0 0 2 2 2 0 CUE domain Mem_trans PF03547.18 ORY92885.1 - 3.2e-43 147.6 0.7 9.3e-34 116.5 0.0 2.2 2 1 0 2 2 2 2 Membrane transport protein Ribosomal_L27A PF00828.19 ORY92887.1 - 5.8e-20 72.3 0.2 7.9e-20 71.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RNA_pol_L_2 PF13656.6 ORY92888.1 - 3.7e-16 58.7 0.0 4.3e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORY92888.1 - 6e-05 22.4 0.0 7.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF667 PF05018.13 ORY92889.1 - 6.6e-24 84.7 0.0 9.4e-21 74.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF667) Clr2_transil PF16761.5 ORY92890.1 - 6.9e-13 49.2 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 CBFB_NFYA PF02045.15 ORY92891.1 - 8.3e-30 103.2 7.9 8.3e-30 103.2 7.9 1.8 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B YAF2_RYBP PF17219.3 ORY92894.1 - 0.002 17.7 0.0 0.75 9.4 0.0 2.5 2 0 0 2 2 2 2 Yaf2/RYBP C-terminal binding motif DNA_repr_REX1B PF14966.6 ORY92895.1 - 4.3e-07 30.5 0.4 0.0059 17.2 0.1 3.0 3 0 0 3 3 3 2 DNA repair REX1-B Ribosomal_L12 PF00542.19 ORY92895.1 - 0.67 10.4 3.3 0.33 11.3 0.4 2.0 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Seryl_tRNA_N PF02403.22 ORY92895.1 - 6.9 7.0 9.1 26 5.1 7.5 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Isochorismatase PF00857.20 ORY92897.1 - 8.5e-37 127.0 0.1 1e-36 126.7 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Methyltransf_25 PF13649.6 ORY92897.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Pirin PF02678.16 ORY92898.1 - 2.1e-25 88.8 0.6 3.4e-25 88.1 0.6 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 ORY92898.1 - 8.3e-05 22.2 4.4 0.0086 15.8 1.3 2.5 2 0 0 2 2 2 2 Cupin domain Pirin_C_2 PF17954.1 ORY92898.1 - 0.00092 19.3 0.0 0.016 15.4 0.0 2.4 1 1 0 1 1 1 1 Quercetinase C-terminal cupin domain CHCH PF06747.13 ORY92899.1 - 6.2e-06 26.2 2.1 9.5e-06 25.6 2.1 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 ORY92899.1 - 0.00026 21.1 0.4 0.00026 21.1 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CX9C PF16860.5 ORY92899.1 - 0.093 12.8 0.8 0.15 12.1 0.8 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 ORY92899.1 - 0.1 12.8 2.4 0.16 12.2 2.4 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type DUF3551 PF12071.8 ORY92899.1 - 4.9 7.3 9.8 0.25 11.4 4.3 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3551) RHD3 PF05879.12 ORY92900.1 - 4.5e-249 828.5 1.5 9e-249 827.5 1.5 1.3 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 ORY92900.1 - 1.1e-06 28.7 0.6 4.1e-06 26.9 0.0 2.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase GBP PF02263.19 ORY92900.1 - 1.3e-06 27.9 0.2 2.4e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 ORY92900.1 - 9e-06 25.8 0.1 2.3e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 ORY92900.1 - 0.0014 18.9 0.0 0.0033 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 ORY92900.1 - 0.052 13.1 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron transport protein B NAAA-beta PF15508.6 ORY92900.1 - 0.11 12.8 0.0 0.48 10.8 0.0 2.1 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TMEM187 PF15100.6 ORY92903.1 - 0.056 13.0 1.2 0.068 12.7 0.6 1.3 1 1 0 1 1 1 0 TMEM187 protein family NDUF_B12 PF08122.12 ORY92903.1 - 0.14 12.2 0.4 0.29 11.2 0.4 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family SLATT_6 PF18169.1 ORY92903.1 - 0.22 11.1 0.4 0.31 10.6 0.4 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Popeye PF04831.13 ORY92903.1 - 1.1 9.4 3.7 0.4 10.8 0.9 1.6 1 1 0 2 2 2 0 Popeye protein conserved region SART-1 PF03343.13 ORY92906.1 - 5.2e-152 507.6 40.9 6.3e-152 507.4 40.9 1.1 1 0 0 1 1 1 1 SART-1 family Glyco_hydr_116N PF12215.8 ORY92906.1 - 0.1 12.0 1.5 0.21 11.0 1.5 1.5 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term MCM3AP_GANP PF16769.5 ORY92906.1 - 0.22 9.7 5.2 0.4 8.9 5.2 1.3 1 0 0 1 1 1 0 MCM3AP domain of GANP Het-C PF07217.11 ORY92909.1 - 2e-213 710.0 0.0 2.6e-213 709.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C TauD PF02668.16 ORY92910.1 - 3.9e-36 125.2 0.0 6e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAO PF01266.24 ORY92911.1 - 5.8e-44 151.1 0.5 7.9e-43 147.4 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 ORY92911.1 - 0.00061 18.7 0.0 0.00089 18.2 0.0 1.1 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 ORY92911.1 - 0.012 15.8 0.3 0.03 14.5 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY92911.1 - 0.018 14.3 0.3 0.031 13.5 0.3 1.3 1 0 0 1 1 1 0 Thi4 family HSP90 PF00183.18 ORY92912.1 - 5.6e-227 754.7 28.6 7e-227 754.4 28.6 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORY92912.1 - 4.9e-15 56.0 0.0 9.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY92912.1 - 1e-09 38.3 0.1 1e-09 38.3 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 ORY92912.1 - 0.21 11.6 0.7 0.47 10.4 0.0 1.9 3 0 0 3 3 3 0 Haem-binding uptake, Tiki superfamily, ChaN DUF2052 PF09747.9 ORY92912.1 - 1.6 8.8 15.6 0.19 11.8 6.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF45 PF01863.17 ORY92912.1 - 9.6 6.2 14.4 9.2 6.2 5.4 3.1 3 0 0 3 3 3 0 Protein of unknown function DUF45 DUF2318 PF10080.9 ORY92913.1 - 0.024 14.8 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) FUR PF01475.19 ORY92913.1 - 0.028 14.6 0.1 0.04 14.1 0.1 1.2 1 0 0 1 1 1 0 Ferric uptake regulator family zf-BED PF02892.15 ORY92913.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 BED zinc finger HypA PF01155.19 ORY92913.1 - 0.13 12.3 0.2 0.13 12.3 0.2 1.8 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA F-box-like PF12937.7 ORY92914.1 - 0.013 15.4 0.2 0.032 14.1 0.2 1.7 1 0 0 1 1 1 0 F-box-like zf-HIT PF04438.16 ORY92916.1 - 7.9e-08 32.0 10.1 1.1e-07 31.5 10.1 1.2 1 0 0 1 1 1 1 HIT zinc finger Nucleo_P87 PF07267.11 ORY92916.1 - 7.6 5.3 6.4 0.91 8.3 1.2 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Anp1 PF03452.14 ORY92917.1 - 1.2e-51 175.7 0.4 6e-31 107.8 0.0 2.6 2 1 0 2 2 2 2 Anp1 Glycos_transf_2 PF00535.26 ORY92917.1 - 0.0079 16.0 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DHDPS PF00701.22 ORY92919.1 - 2.6e-37 128.1 0.0 3.1e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family zf-HIT PF04438.16 ORY92920.1 - 5.8e-08 32.5 9.5 8.4e-08 32.0 9.5 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF4322 PF14210.6 ORY92920.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) MR_MLE_C PF13378.6 ORY92921.1 - 4.6e-49 166.9 1.2 4.2e-48 163.8 1.2 2.2 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 ORY92921.1 - 0.00061 20.0 0.0 0.0015 18.7 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 ORY92921.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus PITH PF06201.13 ORY92922.1 - 7.7e-35 120.3 0.0 9.2e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 PITH domain MSA-2c PF12238.8 ORY92923.1 - 0.45 10.5 1.7 0.86 9.6 1.7 1.5 1 0 0 1 1 1 0 Merozoite surface antigen 2c MFS_1 PF07690.16 ORY92924.1 - 8.1e-18 64.5 21.3 1.2e-17 63.9 21.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 ORY92925.1 - 9.2e-47 160.1 0.3 1.2e-46 159.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Pkinase PF00069.25 ORY92926.1 - 3.3e-65 220.1 0.0 4.4e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92926.1 - 6.4e-30 104.3 0.0 2.6e-29 102.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY92926.1 - 7.8e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY92926.1 - 0.00027 20.4 0.1 0.00045 19.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4106 PF13388.6 ORY92926.1 - 0.00029 20.2 8.2 0.00037 19.8 8.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) Haspin_kinase PF12330.8 ORY92926.1 - 0.0081 15.1 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY92926.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 ORY92926.1 - 0.25 11.2 5.6 1.3 8.9 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family SPATA3 PF15662.5 ORY92926.1 - 4.2 8.0 15.4 7.2 7.2 15.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family Oxidored_FMN PF00724.20 ORY92927.1 - 1.3e-33 116.7 0.0 5.5e-33 114.7 0.0 1.9 2 1 0 2 2 2 1 NADH:flavin oxidoreductase / NADH oxidase family Sulfotransfer_3 PF13469.6 ORY92928.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family zinc_ribbon_10 PF10058.9 ORY92929.1 - 7.3e-17 60.8 0.1 1.1e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Mu-like_Com PF10122.9 ORY92929.1 - 3e-05 23.4 0.0 5.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Mu-like prophage protein Com MRP-L46 PF11788.8 ORY92929.1 - 0.0087 16.8 0.6 0.0087 16.8 0.6 1.9 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 DUF2663 PF10864.8 ORY92929.1 - 0.057 13.8 0.2 0.095 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) BLI1 PF17324.2 ORY92929.1 - 0.067 13.9 2.3 0.12 13.1 2.3 1.3 1 0 0 1 1 1 0 BLOC-1 interactor 1 Sel1 PF08238.12 ORY92930.1 - 6.1e-16 58.5 11.3 4.6e-06 27.1 0.0 5.3 5 0 0 5 5 5 3 Sel1 repeat TPR_6 PF13174.6 ORY92930.1 - 0.00021 21.7 2.0 0.28 11.9 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY92930.1 - 0.00073 20.2 1.6 0.85 10.6 0.0 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY92930.1 - 0.00093 19.1 0.9 0.18 12.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY92930.1 - 0.041 14.1 0.1 0.48 10.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY92930.1 - 0.08 13.0 1.4 0.26 11.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat BNIP3 PF06553.12 ORY92930.1 - 0.11 12.1 2.2 0.89 9.2 0.0 2.5 2 0 0 2 2 2 0 BNIP3 TPR_1 PF00515.28 ORY92930.1 - 0.26 11.2 1.3 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY92930.1 - 6.9 7.4 8.1 2.5 8.8 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA PF00004.29 ORY92932.1 - 4.7e-42 143.5 0.0 8.1e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY92932.1 - 3.7e-10 39.6 0.0 7.6e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY92932.1 - 4.1e-08 32.9 0.4 7.9e-08 32.0 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORY92932.1 - 1.2e-05 25.5 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY92932.1 - 2.4e-05 24.6 0.3 0.029 14.6 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 ORY92932.1 - 4.2e-05 22.8 0.0 7.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY92932.1 - 0.00074 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY92932.1 - 0.00089 19.7 0.2 0.0089 16.4 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY92932.1 - 0.00093 19.2 0.3 0.0058 16.6 0.3 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATPase PF06745.13 ORY92932.1 - 0.0023 17.3 0.2 0.22 10.9 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_3 PF07726.11 ORY92932.1 - 0.006 16.4 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY92932.1 - 0.0073 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY92932.1 - 0.016 15.7 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY92932.1 - 0.031 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 ORY92932.1 - 0.043 13.0 0.1 0.091 11.9 0.1 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 ORY92932.1 - 0.045 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY92932.1 - 0.063 13.2 0.2 0.84 9.5 0.1 2.3 1 1 1 2 2 2 0 NACHT domain Prot_ATP_OB_N PF17758.1 ORY92932.1 - 0.065 12.9 0.1 0.38 10.4 0.0 2.3 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 ORY92932.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY92932.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 ORY92932.1 - 0.13 12.6 0.0 0.35 11.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.21 ORY92932.1 - 0.14 11.5 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ORY92932.1 - 0.15 11.8 0.2 0.31 10.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY92932.1 - 0.26 10.9 0.7 5.2 6.6 0.3 2.4 1 1 1 2 2 2 0 AAA domain Glyco_transf_28 PF03033.20 ORY92933.1 - 1e-25 90.4 0.0 1.9e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 ORY92933.1 - 4.7e-05 22.4 0.0 9.2e-05 21.4 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 ORY92933.1 - 0.00071 20.1 0.1 0.0017 18.8 0.1 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 ORY92933.1 - 0.00099 19.0 0.0 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 GRAM domain COMPASS-Shg1 PF05205.12 ORY92938.1 - 1.4e-07 32.1 0.0 3.2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 ATP-synt_10 PF05176.14 ORY92939.1 - 1.5e-60 204.6 0.0 1.9e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Exo_endo_phos PF03372.23 ORY92940.1 - 1.3e-25 90.3 0.2 3.9e-25 88.7 0.2 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 ORY92940.1 - 1.5e-07 31.6 11.9 0.0017 18.7 1.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY92940.1 - 8e-07 28.7 12.9 2.9e-05 23.7 2.9 2.6 2 1 1 3 3 3 2 Leucine rich repeat Helicase_C_2 PF13307.6 ORY92941.1 - 4.3e-53 180.0 0.0 9.9e-53 178.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ORY92941.1 - 3.2e-48 163.7 0.0 8.7e-48 162.3 0.0 1.7 2 0 0 2 2 2 1 DEAD_2 PhoH PF02562.16 ORY92941.1 - 0.026 14.0 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 ORY92941.1 - 0.052 13.3 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 ORY92941.1 - 0.13 11.4 0.0 9.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ax_dynein_light PF10211.9 ORY92941.1 - 0.14 12.0 4.2 0.039 13.9 0.7 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain DUF222 PF02720.17 ORY92942.1 - 0.054 13.0 2.4 0.081 12.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) Kelch_1 PF01344.25 ORY92943.1 - 2.5e-45 151.8 5.6 1.4e-07 30.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 ORY92943.1 - 8.2e-41 137.8 13.7 4.4e-08 33.0 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY92943.1 - 1.6e-36 123.7 10.5 3.5e-08 33.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 ORY92943.1 - 6.6e-35 117.8 12.1 1.5e-07 31.1 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 ORY92943.1 - 1.7e-34 117.0 11.6 1.9e-05 24.7 0.1 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_3 PF13415.6 ORY92943.1 - 9.1e-34 115.1 22.3 2e-07 31.1 0.0 7.7 7 1 1 8 8 8 6 Galactose oxidase, central domain INCENP_ARK-bind PF03941.15 ORY92945.1 - 1.4e-21 76.2 0.1 1.8e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region HAGH_C PF16123.5 ORY92946.1 - 5.1e-22 78.2 0.1 9.6e-22 77.3 0.1 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORY92946.1 - 2.6e-10 40.6 1.9 1.5e-09 38.1 1.9 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily SMC_N PF02463.19 ORY92949.1 - 3.1e-31 108.5 0.4 4.1e-31 108.1 0.4 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY92949.1 - 2.1e-06 27.8 1.1 7.4e-06 26.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 ORY92949.1 - 1.3e-05 24.2 42.6 0.00049 19.1 11.5 3.2 3 0 0 3 3 3 2 Spc7 kinetochore protein GAS PF13851.6 ORY92949.1 - 3.4e-05 23.3 38.9 0.038 13.3 10.3 3.5 3 0 0 3 3 3 3 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 ORY92949.1 - 6.5e-05 23.0 21.3 0.0018 18.3 6.8 3.8 3 1 0 3 3 3 2 Laminin Domain II BST2 PF16716.5 ORY92949.1 - 0.00014 22.3 29.0 0.00064 20.2 4.3 4.8 3 2 1 4 4 4 1 Bone marrow stromal antigen 2 Filament PF00038.21 ORY92949.1 - 0.00019 21.2 27.2 0.00019 21.2 27.2 2.3 2 0 0 2 2 2 1 Intermediate filament protein WEMBL PF05701.11 ORY92949.1 - 0.00038 19.3 38.9 0.015 14.1 11.9 3.2 3 0 0 3 3 3 3 Weak chloroplast movement under blue light DUF3450 PF11932.8 ORY92949.1 - 0.0015 17.9 6.8 0.0015 17.9 6.8 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3450) DUF1664 PF07889.12 ORY92949.1 - 0.0022 18.0 20.9 0.054 13.5 3.1 4.4 3 3 0 3 3 3 1 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 ORY92949.1 - 0.0028 17.7 45.3 0.0042 17.1 11.8 4.3 3 2 2 5 5 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SbcCD_C PF13558.6 ORY92949.1 - 0.004 17.3 0.0 0.015 15.5 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Fib_alpha PF08702.10 ORY92949.1 - 0.0044 17.2 27.0 0.061 13.5 7.7 4.3 3 1 1 4 4 4 1 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 ORY92949.1 - 0.0087 14.8 29.3 0.083 11.5 7.3 3.2 3 0 0 3 3 3 2 AAA domain DUF812 PF05667.11 ORY92949.1 - 0.011 14.7 36.3 0.036 13.0 11.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 ORY92949.1 - 0.011 15.8 8.1 2.1 8.4 0.2 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 ORY92949.1 - 0.015 14.7 24.7 0.023 14.1 6.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) DUF3584 PF12128.8 ORY92949.1 - 0.018 12.6 43.6 0.026 12.1 33.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Cytochrom_B562 PF07361.11 ORY92949.1 - 0.027 15.1 0.6 0.027 15.1 0.6 4.0 3 0 0 3 3 3 0 Cytochrome b562 DUF713 PF05218.14 ORY92949.1 - 0.038 13.7 13.8 0.2 11.4 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF713) TolA_bind_tri PF16331.5 ORY92949.1 - 0.093 12.8 11.4 6.2 7.0 0.1 3.8 3 1 0 3 3 3 0 TolA binding protein trimerisation ATG16 PF08614.11 ORY92949.1 - 0.094 12.9 44.9 0.13 12.4 14.3 3.7 3 2 0 3 3 3 0 Autophagy protein 16 (ATG16) IFT57 PF10498.9 ORY92949.1 - 0.1 11.6 29.3 0.026 13.5 6.7 3.2 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 YabA PF06156.13 ORY92949.1 - 0.1 13.3 26.7 0.79 10.4 3.3 4.5 3 1 1 4 4 4 0 Initiation control protein YabA DUF2730 PF10805.8 ORY92949.1 - 0.1 12.7 14.4 0.97 9.6 1.5 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 ORY92949.1 - 0.11 11.8 41.2 0.1 11.9 12.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 ORY92949.1 - 0.13 12.2 42.1 0.3 11.1 9.4 6.2 3 3 3 6 6 5 0 Prefoldin subunit HMMR_N PF15905.5 ORY92949.1 - 0.14 11.6 37.4 0.037 13.5 10.8 3.2 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal YgaB PF14182.6 ORY92949.1 - 0.16 12.4 23.8 0.039 14.3 4.9 5.2 4 2 0 4 4 3 0 YgaB-like protein CEP63 PF17045.5 ORY92949.1 - 0.21 11.5 35.1 0.064 13.1 26.7 3.1 2 1 0 2 2 2 0 Centrosomal protein of 63 kDa OmpH PF03938.14 ORY92949.1 - 0.21 11.9 42.2 0.12 12.8 3.7 3.9 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF5082 PF16888.5 ORY92949.1 - 0.22 11.8 33.5 0.28 11.5 2.6 5.8 4 3 2 6 6 6 0 Domain of unknown function (DUF5082) DUF16 PF01519.16 ORY92949.1 - 0.24 11.9 36.2 4.1 7.9 5.3 5.6 2 2 2 4 4 4 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 ORY92949.1 - 0.27 11.7 11.1 13 6.4 2.2 4.8 3 3 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KxDL PF10241.9 ORY92949.1 - 0.28 11.5 21.3 1.7 8.9 3.5 4.6 3 3 1 4 4 4 0 Uncharacterized conserved protein Spectrin PF00435.21 ORY92949.1 - 0.29 11.6 27.2 1 9.9 5.2 4.9 3 2 1 4 4 4 0 Spectrin repeat DUF2968 PF11180.8 ORY92949.1 - 0.29 10.7 23.4 0.31 10.7 7.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2968) Golgin_A5 PF09787.9 ORY92949.1 - 0.3 10.5 44.4 0.097 12.1 11.9 4.3 2 1 2 4 4 4 0 Golgin subfamily A member 5 Ribosomal_L29 PF00831.23 ORY92949.1 - 0.3 11.1 15.9 2.1 8.4 0.1 4.3 2 1 1 3 3 3 0 Ribosomal L29 protein HAP1_N PF04849.13 ORY92949.1 - 0.31 10.2 35.9 0.16 11.1 10.4 3.0 2 1 1 3 3 3 0 HAP1 N-terminal conserved region FixO PF02433.15 ORY92949.1 - 0.32 10.4 7.4 0.033 13.6 1.5 2.3 2 1 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO PEARLI-4 PF05278.12 ORY92949.1 - 0.62 9.6 23.3 0.11 12.1 8.1 2.7 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Sec8_exocyst PF04048.14 ORY92949.1 - 0.65 9.9 18.5 0.33 10.8 2.1 4.2 3 3 1 4 4 4 0 Sec8 exocyst complex component specific domain CENP-Q PF13094.6 ORY92949.1 - 0.77 9.9 33.3 1.2 9.3 16.0 3.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.6 ORY92949.1 - 0.84 9.7 31.2 6.2 6.9 2.6 5.4 3 2 2 5 5 5 0 FlxA-like protein TPR_MLP1_2 PF07926.12 ORY92949.1 - 0.85 9.7 48.3 1.1 9.3 14.8 4.4 3 3 0 3 3 3 0 TPR/MLP1/MLP2-like protein End3 PF12761.7 ORY92949.1 - 0.97 9.6 23.7 0.065 13.4 2.6 2.9 3 0 0 3 3 2 0 Actin cytoskeleton-regulatory complex protein END3 SlyX PF04102.12 ORY92949.1 - 1.3 9.7 24.6 5.7 7.6 3.1 6.0 3 2 1 5 5 5 0 SlyX NPBW PF15180.6 ORY92949.1 - 1.4 8.8 5.2 20 5.1 0.0 3.3 3 0 0 3 3 3 0 Neuropeptides B and W DUF2408 PF10303.9 ORY92949.1 - 1.6 9.3 30.5 0.86 10.2 2.6 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2408) Lebercilin PF15619.6 ORY92949.1 - 1.9 8.1 38.5 0.5 10.0 9.8 3.9 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 ORY92949.1 - 2 8.7 41.0 0.88 9.8 13.3 5.0 3 2 1 5 5 5 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 ORY92949.1 - 2 8.5 35.5 0.21 11.7 7.3 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Snapin_Pallidin PF14712.6 ORY92949.1 - 2.9 8.4 22.7 1.7 9.1 3.1 4.7 4 2 0 5 5 3 0 Snapin/Pallidin EzrA PF06160.12 ORY92949.1 - 3 5.9 39.6 0.55 8.3 0.7 4.3 3 2 1 4 4 4 0 Septation ring formation regulator, EzrA LMBR1 PF04791.16 ORY92949.1 - 3.5 6.4 15.6 0.025 13.5 1.2 2.2 1 1 1 2 2 2 0 LMBR1-like membrane protein APG6_N PF17675.1 ORY92949.1 - 3.6 8.1 54.7 0.095 13.2 17.0 4.3 2 1 0 3 3 3 0 Apg6 coiled-coil region TMPIT PF07851.13 ORY92949.1 - 4.2 6.5 25.8 2.3 7.4 2.0 3.7 2 1 1 4 4 4 0 TMPIT-like protein BLOC1_2 PF10046.9 ORY92949.1 - 4.2 7.7 25.6 0.43 10.9 3.4 4.6 3 3 1 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.7 ORY92949.1 - 4.6 6.7 36.6 4 6.9 10.7 4.1 3 2 0 3 3 3 0 Mechanosensitive ion channel porin domain Bacillus_HBL PF05791.11 ORY92949.1 - 5 6.9 20.4 0.56 10.0 1.7 3.4 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Fmp27_WPPW PF10359.9 ORY92949.1 - 5.4 5.8 27.0 0.6 8.9 5.3 3.1 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Halo_GVPC PF05465.13 ORY92949.1 - 5.6 7.3 6.7 17 5.8 0.1 3.1 3 0 0 3 3 2 0 Halobacterial gas vesicle protein C (GVPC) repeat SOGA PF11365.8 ORY92949.1 - 7.1 7.8 29.1 4.4 8.5 11.7 4.6 3 1 0 3 3 3 0 Protein SOGA DASH_Dam1 PF08653.10 ORY92949.1 - 7.5 6.4 8.1 1.4e+02 2.4 0.0 4.9 5 1 1 6 6 5 0 DASH complex subunit Dam1 COG5 PF10392.9 ORY92949.1 - 7.7 6.7 18.3 2.5 8.3 2.6 3.6 3 2 0 3 3 3 0 Golgi transport complex subunit 5 Prefoldin_3 PF13758.6 ORY92949.1 - 8 6.6 22.1 0.84 9.7 2.6 4.3 3 1 0 3 3 3 0 Prefoldin subunit HemX PF04375.14 ORY92949.1 - 8.6 5.5 26.3 0.84 8.9 5.9 3.3 3 1 0 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase COG2 PF06148.11 ORY92949.1 - 8.7 6.4 26.9 3.7 7.6 6.0 4.4 3 3 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 LapA_dom PF06305.11 ORY92950.1 - 0.091 12.6 3.1 0.26 11.1 0.1 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain PgaD PF13994.6 ORY92950.1 - 8.4 6.4 9.3 0.17 11.9 0.7 2.5 3 0 0 3 3 3 0 PgaD-like protein RNA_pol_L_2 PF13656.6 ORY92951.1 - 1e-29 102.1 0.1 1.4e-29 101.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORY92951.1 - 1.2e-06 27.8 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF853 PF05872.12 ORY92951.1 - 0.045 12.3 1.0 0.049 12.2 1.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CBFD_NFYB_HMF PF00808.23 ORY92952.1 - 2.5e-09 37.3 0.0 4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 ORY92952.1 - 0.037 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Histone PF00125.24 ORY92952.1 - 0.15 12.4 0.6 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 NOA36 PF06524.12 ORY92952.1 - 1.6 8.0 5.6 2 7.7 5.6 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 ORY92952.1 - 1.9 8.0 9.5 2.4 7.7 9.5 1.2 1 0 0 1 1 1 0 PPP4R2 Hexapep PF00132.24 ORY92953.1 - 1.8e-07 30.6 16.6 0.0048 16.6 0.3 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORY92953.1 - 0.0006 19.5 17.2 0.0049 16.6 3.2 3.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY92953.1 - 1.7 7.5 2.7 0.74 8.7 0.4 1.5 2 0 0 2 2 2 0 L-fucokinase Pkinase PF00069.25 ORY92954.1 - 4.4e-66 222.9 0.0 5.3e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY92954.1 - 9.3e-32 110.3 0.0 2.6e-31 108.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY92954.1 - 0.003 16.6 0.1 0.0048 15.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY92954.1 - 0.016 14.5 0.4 0.034 13.5 0.4 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY92954.1 - 0.021 14.8 0.3 0.05 13.5 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY92954.1 - 0.049 12.9 0.0 0.087 12.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Mpv17_PMP22 PF04117.12 ORY92955.1 - 4.4e-24 84.5 0.5 7.4e-24 83.8 0.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Prenyltrans PF00432.21 ORY92956.1 - 1.7e-26 91.7 18.7 1.2e-08 34.5 0.0 7.0 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat GTP1_OBG PF01018.22 ORY92957.1 - 2.9e-36 124.4 0.8 1.3e-26 93.1 1.6 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 ORY92957.1 - 1.1e-19 70.6 0.0 5.3e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY92957.1 - 2.2e-05 24.0 0.1 9e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 ORY92957.1 - 0.0004 20.9 0.4 0.0016 19.0 0.0 2.2 3 0 0 3 3 3 1 ABC transporter Dynamin_N PF00350.23 ORY92957.1 - 0.0022 18.1 0.0 0.015 15.3 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 ORY92957.1 - 0.0048 16.5 0.0 0.11 12.1 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.21 ORY92957.1 - 0.017 14.6 1.8 6.5 6.2 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family Thi4 PF01946.17 ORY92957.1 - 0.04 13.2 0.1 0.07 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family MeaB PF03308.16 ORY92957.1 - 0.061 12.3 1.1 0.27 10.2 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 ORY92957.1 - 0.23 11.2 0.0 28 4.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 ORY92957.1 - 0.38 11.3 3.7 0.44 11.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain BTB PF00651.31 ORY92958.1 - 9.2e-10 38.7 0.2 0.00085 19.5 0.0 3.2 2 1 0 2 2 2 2 BTB/POZ domain HrpB7 PF09486.10 ORY92959.1 - 0.78 10.1 19.6 0.61 10.5 1.9 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 ORY92959.1 - 1 8.7 18.7 1.3 8.4 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 ORY92959.1 - 1.2 6.6 18.5 1.6 6.2 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ESM4 PF15952.5 ORY92959.1 - 1.3 9.4 10.6 1.6 9.1 10.6 1.1 1 0 0 1 1 1 0 Enhancer of split M4 family Spc7 PF08317.11 ORY92959.1 - 1.3 7.8 17.8 1.7 7.4 17.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Presenilin PF01080.17 ORY92959.1 - 2 7.1 8.1 2.4 6.9 8.1 1.2 1 0 0 1 1 1 0 Presenilin DUF16 PF01519.16 ORY92959.1 - 2.3 8.8 16.5 1.2 9.7 6.5 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF5446 PF17522.2 ORY92959.1 - 4.4 7.5 5.5 3.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5446) BRE1 PF08647.11 ORY92959.1 - 5.5 7.1 22.8 1.3 9.2 7.8 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase MAJIN PF15077.6 ORY92959.1 - 6 6.6 8.1 7.6 6.2 8.1 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein RR_TM4-6 PF06459.12 ORY92959.1 - 7.6 6.3 17.7 9.3 6.0 17.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ALMT PF11744.8 ORY92959.1 - 8.7 5.1 9.7 11 4.8 9.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 ORY92959.1 - 9.5 4.0 7.7 11 3.8 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.16 ORY92960.1 - 1.2e-40 139.6 48.3 1.6e-39 135.9 43.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY92960.1 - 4.2e-10 39.1 9.7 4.2e-10 39.1 9.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 ORY92960.1 - 0.0035 16.7 30.8 0.031 13.6 14.1 2.6 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB Carn_acyltransf PF00755.20 ORY92960.1 - 0.31 9.6 0.0 0.45 9.1 0.0 1.1 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase SMC_N PF02463.19 ORY92961.1 - 6.9e-55 185.9 0.0 1.5e-54 184.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY92961.1 - 2.1e-29 102.2 0.0 6e-29 100.7 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY92961.1 - 1.6e-14 54.4 0.4 1.9e-07 31.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY92961.1 - 3.9e-07 30.8 31.1 3.9e-07 30.8 31.1 6.4 3 2 2 5 5 4 1 AAA domain AAA_29 PF13555.6 ORY92961.1 - 1.6e-06 27.7 0.0 3.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 ORY92961.1 - 2.5e-05 23.3 29.0 8.1e-05 21.6 7.0 6.0 4 1 2 6 6 6 3 Spc7 kinetochore protein Filament PF00038.21 ORY92961.1 - 0.00016 21.4 22.9 0.00016 21.4 22.9 5.1 3 1 2 5 5 3 1 Intermediate filament protein AAA_15 PF13175.6 ORY92961.1 - 0.0003 20.6 25.5 0.0003 20.6 25.5 4.8 3 2 0 3 3 2 1 AAA ATPase domain DUF3450 PF11932.8 ORY92961.1 - 0.00032 20.1 6.2 0.00032 20.1 6.2 6.6 4 1 4 8 8 8 2 Protein of unknown function (DUF3450) SbcCD_C PF13558.6 ORY92961.1 - 0.0097 16.1 0.0 0.037 14.3 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 ORY92961.1 - 0.042 14.4 0.0 0.042 14.4 0.0 5.9 5 2 0 5 5 4 0 ABC transporter Laminin_II PF06009.12 ORY92961.1 - 0.79 9.7 44.5 0.27 11.2 1.3 6.9 5 1 1 6 6 6 0 Laminin Domain II DUF1664 PF07889.12 ORY92961.1 - 5.3 7.1 46.7 0.076 13.0 0.9 7.3 5 3 1 6 6 6 0 Protein of unknown function (DUF1664) DUF3618 PF12277.8 ORY92961.1 - 7 7.0 13.0 1 9.7 4.9 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) COG5 PF10392.9 ORY92961.1 - 7.3 6.8 30.6 0.31 11.2 2.9 4.8 5 1 1 6 6 6 0 Golgi transport complex subunit 5 Hydrolase_6 PF13344.6 ORY92962.1 - 2.6e-20 72.4 0.0 9.3e-20 70.6 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY92962.1 - 1.8e-17 63.2 0.0 3.1e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 ORY92962.1 - 6e-09 36.2 0.8 0.0016 18.6 0.0 2.9 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY92962.1 - 2.1e-06 28.2 0.0 2.4e-05 24.7 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 ORY92962.1 - 0.0024 17.5 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase_3 PF08282.12 ORY92962.1 - 0.068 12.9 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Aa_trans PF01490.18 ORY92963.1 - 2.7e-32 112.0 26.5 3.4e-32 111.7 26.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bac_export_1 PF01311.20 ORY92963.1 - 0.0037 16.9 5.3 0.0037 16.9 5.3 2.3 3 0 0 3 3 3 1 Bacterial export proteins, family 1 7TM_GPCR_Srsx PF10320.9 ORY92963.1 - 1.6 8.0 12.4 2.2 7.6 3.2 2.5 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx Aldo_ket_red PF00248.21 ORY92964.1 - 4.3e-39 134.5 0.0 2.3e-37 128.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 ORY92965.1 - 5e-07 29.7 9.2 7.8e-07 29.1 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F_actin_bind PF08919.10 ORY92966.1 - 0.18 11.9 0.1 7.3 6.7 0.0 2.2 2 0 0 2 2 2 0 F-actin binding XPG_I PF00867.18 ORY92967.1 - 4.1e-15 55.9 0.0 1.1e-14 54.6 0.0 1.7 1 1 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY92967.1 - 6.5e-08 33.0 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 ORY92967.1 - 0.0027 18.3 0.0 0.011 16.4 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 ORY92967.1 - 0.098 12.8 0.2 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix motif Methyltransf_24 PF13578.6 ORY92967.1 - 0.14 13.2 0.2 0.48 11.5 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 ORY92968.1 - 1.9e-53 180.4 0.0 2.6e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY92968.1 - 2.9e-19 69.1 0.0 3.5e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY92968.1 - 1.3e-05 25.4 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY92968.1 - 0.032 14.8 0.0 0.087 13.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 ORY92968.1 - 0.12 12.3 0.1 8.1 6.3 0.0 2.5 2 1 0 2 2 2 0 Rossmann-like domain 2-Hacid_dh_C PF02826.19 ORY92969.1 - 6.2e-53 178.8 0.0 9.5e-53 178.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY92969.1 - 5.3e-15 55.3 0.0 6.1e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY92969.1 - 1.6e-07 31.6 0.0 2.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 ORY92969.1 - 0.0013 19.2 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 ORY92969.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 ORY92969.1 - 0.03 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain UBM PF14377.6 ORY92969.1 - 0.13 11.8 0.3 23 4.6 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin binding region WD40 PF00400.32 ORY92970.1 - 2.4e-13 50.3 0.5 0.013 16.4 0.0 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY92970.1 - 0.0037 17.5 0.0 9.2 6.7 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RF-1 PF00472.20 ORY92971.1 - 1.3e-19 70.2 0.3 1.9e-19 69.7 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain XPG_I PF00867.18 ORY92972.1 - 7.8e-15 55.0 0.0 2e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY92972.1 - 5.4e-07 30.0 0.0 1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 ORY92972.1 - 0.12 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold F-box-like PF12937.7 ORY92973.1 - 0.0031 17.4 0.1 0.0082 16.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Leucosporidiella_creatinivora_62-1032-Leucr1/GCA_002105055.1_Leucr1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Leucosporidiella_creatinivora_62-1032-Leucr1/GCA_002105055.1_Leucr1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Leucosporidiella_creatinivora_62-1032-Leucr1/GCA_002105055.1_Leucr1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Leucosporidiella_creatinivora_62-1032-Leucr1/GCA_002105055.1_Leucr1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 23:01:52 2019 # [ok]