# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Polyketide_cyc2 PF10604.9 CAR21032.1 - 2.3e-06 27.9 0.0 2.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DJ-1_PfpI PF01965.24 CAR21034.1 - 2.5e-51 173.8 0.0 2.9e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 CAR21034.1 - 8.5e-05 22.4 0.0 0.0001 22.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ThiJ_like PF17124.5 CAR21034.1 - 8.8e-05 22.3 0.0 0.00022 21.0 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like Catalase_C PF18011.1 CAR21034.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 C-terminal domain found in long catalases GATase_3 PF07685.14 CAR21034.1 - 0.00078 19.1 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 CAR21034.1 - 0.0033 17.2 0.1 0.01 15.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 SNO PF01174.19 CAR21034.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DUP PF00674.18 CAR21035.1 - 0.00045 20.3 0.0 0.00069 19.7 0.0 1.3 1 0 0 1 1 1 1 DUP family Gemini_AL1_M PF08283.11 CAR21035.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Geminivirus rep protein central domain AA_permease PF00324.21 CAR21036.1 - 2.2e-93 313.4 37.7 2.7e-93 313.1 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR21036.1 - 9.3e-24 84.0 42.7 2.3e-23 82.7 42.7 1.6 1 1 0 1 1 1 1 Amino acid permease FMN_bind_2 PF04299.12 CAR21037.1 - 3e-59 199.5 0.0 4.2e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Putative FMN-binding domain Pyridox_ox_2 PF12900.7 CAR21037.1 - 0.0045 17.0 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ADH_N PF08240.12 CAR21038.1 - 9.8e-28 96.2 0.2 1.9e-27 95.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR21038.1 - 3.9e-24 85.1 0.4 6e-24 84.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR21038.1 - 4.8e-05 24.4 0.0 7.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CAR21038.1 - 0.02 14.2 0.8 0.039 13.2 0.3 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 CAR21038.1 - 0.041 13.6 0.4 0.071 12.8 0.4 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase MFS_1 PF07690.16 CAR21039.1 - 1.4e-28 99.9 24.7 1.4e-28 99.9 24.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Ost5 PF05251.12 CAR21039.1 - 0.36 11.1 0.1 0.36 11.1 0.1 4.9 7 0 0 7 7 7 0 Oligosaccharyltransferase subunit 5 IU_nuc_hydro PF01156.19 CAR21040.1 - 2.2e-36 126.0 0.2 2.8e-36 125.6 0.2 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ATP-synt_DE_N PF02823.16 CAR21040.1 - 0.049 13.5 0.2 5.5 7.0 0.0 3.0 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Transketolase_C PF02780.20 CAR21040.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans_2 PF11951.8 CAR21041.1 - 5.4e-44 150.6 0.0 6.6e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21041.1 - 0.00012 22.1 12.8 0.00025 21.1 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApbA_C PF08546.11 CAR21042.1 - 2.3e-33 115.1 0.0 6.7e-33 113.6 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CAR21042.1 - 3.8e-25 88.3 0.0 5.5e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 CAR21043.1 - 2.7e-46 158.1 0.0 1e-44 153.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Flo11 PF10182.9 CAR21044.1 - 1.1e-53 181.4 3.0 2.3e-53 180.4 3.0 1.6 1 0 0 1 1 1 1 Flo11 domain Ferric_reduct PF01794.19 CAR21045.1 - 7.2e-22 77.8 13.8 2.5e-21 76.1 13.8 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CAR21045.1 - 5.2e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CAR21045.1 - 1.1e-07 32.1 0.0 9.1e-05 22.6 0.0 2.2 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Peptidase_M16 PF00675.20 CAR21046.1 - 1.7e-24 86.5 0.0 2.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAR21046.1 - 1.2e-08 35.1 0.0 4.3e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Mak_N_cap PF18085.1 CAR21046.1 - 0.018 16.0 0.3 3.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Maltokinase N-terminal cap domain RNA_pol_Rpc82 PF05645.13 CAR21047.1 - 1.7e-52 178.8 0.0 2.7e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CAR21047.1 - 2.3e-22 78.8 4.4 3e-19 68.9 0.4 3.6 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CAR21047.1 - 4.4e-09 36.1 0.5 1.9e-05 24.5 0.1 2.9 3 0 0 3 3 3 2 TFIIE alpha subunit HTH_IclR PF09339.10 CAR21047.1 - 0.00046 19.9 0.1 0.0021 17.8 0.1 2.2 2 0 0 2 2 2 1 IclR helix-turn-helix domain HTH_24 PF13412.6 CAR21047.1 - 0.0021 17.6 0.1 0.099 12.2 0.0 3.3 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 CAR21047.1 - 0.0061 16.4 0.4 0.029 14.3 0.2 2.3 2 0 0 2 2 2 1 MarR family Penicillinase_R PF03965.16 CAR21047.1 - 0.032 14.6 0.0 0.095 13.1 0.0 1.9 1 0 0 1 1 1 0 Penicillinase repressor TSC22 PF01166.18 CAR21047.1 - 0.11 12.8 2.5 0.13 12.5 0.5 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family TrmB PF01978.19 CAR21047.1 - 0.14 12.0 1.7 0.68 9.9 0.1 3.0 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB TPR_22 PF18833.1 CAR21048.1 - 4.5e-43 145.3 0.4 1.7e-42 143.4 0.4 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR21048.1 - 4e-26 91.3 1.3 8e-05 23.1 0.0 9.7 8 3 1 9 9 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR21048.1 - 3.5e-22 76.7 18.4 0.00026 20.9 0.0 13.4 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAR21048.1 - 3e-21 74.3 7.7 0.00088 19.9 0.0 12.7 10 3 4 14 14 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 CAR21048.1 - 3.6e-20 70.9 12.8 0.00015 21.5 0.0 12.3 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAR21048.1 - 1.7e-18 66.0 3.2 1.4e-06 27.9 0.0 8.6 7 2 2 9 9 9 4 TPR repeat TPR_16 PF13432.6 CAR21048.1 - 2.5e-18 66.4 11.3 2.7e-06 27.9 0.0 9.7 9 2 2 11 11 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAR21048.1 - 2.3e-17 61.7 19.2 5.6e-05 23.0 0.0 11.6 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 CAR21048.1 - 3.3e-12 46.2 2.9 0.092 13.4 0.0 8.7 10 0 0 10 10 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR21048.1 - 1.1e-10 41.7 11.0 0.055 13.8 0.0 8.5 8 2 1 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR21048.1 - 1.4e-10 40.8 7.5 1.1 9.8 0.0 11.2 14 0 0 14 14 11 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAR21048.1 - 8.7e-10 37.9 10.6 0.052 13.6 0.0 9.6 12 0 0 12 12 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR21048.1 - 1e-08 35.3 13.0 0.0014 18.8 0.0 7.1 7 2 1 8 8 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CAR21048.1 - 2.5e-08 33.9 2.5 0.011 15.9 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CAR21048.1 - 0.00014 21.4 3.3 0.0013 18.2 0.2 3.3 3 1 0 3 3 3 1 Coatomer epsilon subunit TPR_MalT PF17874.1 CAR21048.1 - 0.00038 19.9 0.7 3.5 6.9 0.0 4.1 4 0 0 4 4 4 1 MalT-like TPR region HrpB1_HrpK PF09613.10 CAR21048.1 - 0.00081 19.0 0.0 0.053 13.2 0.0 3.1 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) DUF1450 PF07293.11 CAR21048.1 - 0.0012 18.6 0.0 0.0039 17.0 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1450) Alkyl_sulf_dimr PF14863.6 CAR21048.1 - 0.0022 18.4 1.0 2.2 8.7 0.0 3.4 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_10 PF13374.6 CAR21048.1 - 0.007 16.2 5.5 1 9.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 CAR21048.1 - 0.0074 16.6 4.4 12 6.3 0.0 6.3 5 3 3 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 CAR21048.1 - 0.013 15.7 0.5 16 6.0 0.0 3.9 3 0 0 3 3 3 0 PPR repeat Chlorophyllase PF07224.11 CAR21048.1 - 0.1 11.6 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Fis1_TPR_C PF14853.6 CAR21048.1 - 0.11 12.6 5.2 8.6 6.5 0.1 5.3 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 CAR21048.1 - 0.25 11.4 2.2 2.3 8.3 0.1 3.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) DUF4363 PF14276.6 CAR21048.1 - 1.4 9.0 9.2 7.7 6.7 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4363) RPN7 PF10602.9 CAR21048.1 - 2.7 7.7 7.5 3 7.5 0.1 4.0 4 1 0 4 4 4 0 26S proteasome subunit RPN7 RNA_pol_Rpb6 PF01192.22 CAR21049.1 - 3.1e-17 62.2 0.1 4.9e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 CAR21050.1 - 5.8e-30 102.1 64.2 1.3e-05 25.4 4.7 9.3 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR21050.1 - 3e-26 89.8 66.7 0.0002 21.9 1.8 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR21050.1 - 1.1e-15 57.3 67.9 6.9e-05 23.1 4.5 10.6 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CAR21050.1 - 6.5e-07 29.5 36.0 0.14 12.4 1.1 8.2 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR21050.1 - 1.1e-05 25.6 35.6 0.31 11.5 0.6 8.8 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CAR21050.1 - 0.00061 19.5 0.8 0.00061 19.5 0.8 5.1 5 0 0 5 5 5 1 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CAR21050.1 - 0.024 14.7 2.3 0.024 14.7 2.3 4.4 4 1 1 5 5 4 0 Zinc ribbon domain zf-C2H2_8 PF15909.5 CAR21050.1 - 0.076 13.3 27.9 0.26 11.6 2.9 5.1 2 1 3 5 5 5 0 C2H2-type zinc ribbon zf-C2H2_2 PF12756.7 CAR21050.1 - 0.19 12.1 41.2 0.62 10.4 11.6 6.4 2 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) CpXC PF14353.6 CAR21050.1 - 0.29 11.2 0.1 0.29 11.2 0.1 5.7 1 1 1 5 5 5 0 CpXC protein MqsA_antitoxin PF15731.5 CAR21050.1 - 0.62 10.2 6.9 9.8 6.3 0.4 3.6 2 1 1 3 3 3 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA zf-ribbon_3 PF13248.6 CAR21050.1 - 1.4 8.4 14.4 2.3 7.8 0.1 4.8 4 0 0 4 4 4 0 zinc-ribbon domain zf-LYAR PF08790.11 CAR21050.1 - 4.9 7.2 15.5 1.3 9.0 0.3 5.7 6 0 0 6 6 6 0 LYAR-type C2HC zinc finger ATG13 PF10033.9 CAR21051.1 - 4.6e-68 229.5 0.0 1.2e-67 228.1 0.0 1.7 2 0 0 2 2 2 1 Autophagy-related protein 13 hDGE_amylase PF14701.6 CAR21052.1 - 3.9e-179 596.3 0.0 6e-179 595.7 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CAR21052.1 - 5.9e-128 427.0 0.0 8.6e-128 426.5 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CAR21052.1 - 2.5e-75 253.5 0.0 4e-75 252.8 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CAR21052.1 - 1.2e-22 79.9 0.0 3.1e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CAR21052.1 - 4.9e-06 26.3 0.1 1.4e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glycos_transf_2 PF00535.26 CAR21053.1 - 3e-30 105.2 0.0 4.2e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CAR21053.1 - 3.8e-07 30.3 0.0 6.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CAR21053.1 - 0.036 13.5 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 LSM PF01423.22 CAR21054.1 - 3.4e-18 65.1 0.1 4.1e-18 64.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain PIG-U PF06728.13 CAR21055.1 - 1.1e-100 337.4 41.1 1.5e-100 336.9 41.1 1.2 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Sec23_trunk PF04811.15 CAR21056.1 - 7.2e-74 248.4 0.0 9.8e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CAR21056.1 - 2.4e-29 101.9 0.1 4.6e-29 101.0 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CAR21056.1 - 1.1e-26 92.7 0.0 2.1e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CAR21056.1 - 1.8e-13 50.3 3.8 3.1e-13 49.5 3.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CAR21056.1 - 1.6e-11 44.0 0.0 2.8e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CAR21056.1 - 0.0025 17.1 0.3 0.0054 16.1 0.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-MIZ PF02891.20 CAR21056.1 - 0.012 15.3 0.9 0.025 14.3 0.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger VWA_2 PF13519.6 CAR21056.1 - 0.095 13.4 0.0 17 6.1 0.0 2.6 2 0 0 2 2 2 0 von Willebrand factor type A domain ThiF PF00899.21 CAR21057.1 - 4.5e-28 98.2 0.0 7.8e-28 97.5 0.0 1.4 1 1 0 1 1 1 1 ThiF family TetR_C_4 PF08359.11 CAR21057.1 - 0.12 12.6 0.1 0.84 9.8 0.1 2.2 1 1 1 2 2 2 0 YsiA-like protein, C-terminal region HDA2-3 PF11496.8 CAR21058.1 - 4.3e-88 295.3 0.1 4.3e-88 295.3 0.1 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 UPF0242 PF06785.11 CAR21058.1 - 0.01 16.0 24.8 0.01 16.0 24.8 2.3 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Hemerythrin PF01814.23 CAR21058.1 - 0.09 13.4 5.9 0.35 11.5 1.2 2.5 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Sulfotransfer_3 PF13469.6 CAR21058.1 - 0.19 12.1 2.5 0.39 11.1 0.1 2.3 2 0 0 2 2 2 0 Sulfotransferase family NPV_P10 PF05531.12 CAR21058.1 - 0.22 12.0 11.6 37 4.9 3.2 4.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.32 CAR21059.1 - 2.1e-40 136.0 26.3 3.4e-11 43.5 0.2 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21059.1 - 4.8e-16 58.8 1.2 0.0032 17.7 0.0 6.1 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR21059.1 - 1.5e-05 24.9 0.0 0.026 14.4 0.0 2.8 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR21059.1 - 0.0029 16.6 0.0 0.047 12.6 0.0 2.7 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CAR21059.1 - 0.017 14.5 0.0 0.18 11.1 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain Prenyltrans PF00432.21 CAR21060.1 - 7.9e-63 207.9 3.3 1.2e-11 44.1 0.0 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CAR21060.1 - 1.8e-06 27.3 0.0 1.5e-05 24.3 0.0 2.1 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CAR21060.1 - 8.8e-05 21.7 0.0 3.1 6.8 0.0 4.4 1 1 4 5 5 5 2 Squalene-hopene cyclase N-terminal domain DNA_pol_E_B PF04042.16 CAR21061.1 - 2.2e-52 177.5 0.0 3.4e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4047 PF13256.6 CAR21061.1 - 0.16 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) NBP1 PF08537.10 CAR21062.1 - 1.7e-77 261.2 16.2 1.7e-74 251.3 11.4 2.0 1 1 1 2 2 2 2 Fungal Nap binding protein NBP1 DUF2408 PF10303.9 CAR21062.1 - 0.0068 17.0 1.2 0.011 16.3 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) ZapB PF06005.12 CAR21062.1 - 0.83 10.1 10.0 1.5 9.3 2.4 2.6 2 0 0 2 2 2 0 Cell division protein ZapB AAA PF00004.29 CAR21063.1 - 8.5e-43 145.9 0.0 2e-42 144.8 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CAR21063.1 - 1.1e-29 102.2 0.1 4.8e-29 100.2 0.2 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CAR21063.1 - 7.8e-23 80.3 2.3 2.1e-22 78.9 2.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CAR21063.1 - 1.9e-08 34.0 0.1 3.6e-07 29.9 0.0 2.9 4 0 0 4 4 2 1 AAA+ lid domain AAA_16 PF13191.6 CAR21063.1 - 1.8e-05 25.2 0.5 0.00068 20.1 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CAR21063.1 - 1.8e-05 24.8 0.0 9.8e-05 22.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR21063.1 - 2.1e-05 24.8 0.1 0.0019 18.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAR21063.1 - 2.2e-05 24.2 0.0 4.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CAR21063.1 - 3.1e-05 23.8 0.0 7.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CAR21063.1 - 0.00021 21.3 0.0 0.00083 19.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CAR21063.1 - 0.00022 20.5 0.0 0.001 18.3 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CAR21063.1 - 0.00034 19.9 0.0 0.00064 19.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CAR21063.1 - 0.00039 20.8 0.1 0.026 14.9 0.0 2.9 3 0 0 3 3 3 1 RNA helicase AAA_2 PF07724.14 CAR21063.1 - 0.0006 20.0 0.1 0.0014 18.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CAR21063.1 - 0.00065 20.3 0.3 0.0019 18.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAR21063.1 - 0.0014 18.3 0.1 0.059 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR21063.1 - 0.0015 18.7 0.0 0.0051 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CAR21063.1 - 0.014 15.8 0.2 0.048 14.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAR21063.1 - 0.016 14.8 0.2 0.72 9.4 0.1 2.5 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAR21063.1 - 0.036 13.6 0.0 0.096 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CAR21063.1 - 0.039 13.2 0.2 1.1 8.4 0.0 2.8 1 1 2 3 3 3 0 Zeta toxin PhoH PF02562.16 CAR21063.1 - 0.044 13.2 0.1 0.096 12.1 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 CAR21063.1 - 0.044 13.2 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 CAR21063.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.27 CAR21063.1 - 0.053 14.0 0.3 1.1 9.8 0.0 2.6 2 1 1 3 3 3 0 ABC transporter Use1 PF09753.9 CAR21063.1 - 0.064 13.0 2.1 0.12 12.0 2.1 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 ATPase PF06745.13 CAR21063.1 - 0.11 11.8 0.2 10 5.4 0.1 2.3 1 1 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 CAR21063.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CAR21063.1 - 0.14 12.0 0.0 1.3 8.9 0.0 2.2 1 1 0 1 1 1 0 NACHT domain Putative_PNPOx PF01243.20 CAR21064.1 - 6.3e-13 48.7 0.0 4.3e-12 46.1 0.0 2.3 3 1 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 CAR21064.1 - 0.00018 21.5 0.0 0.54 10.3 0.1 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 CAR21064.1 - 0.0036 17.3 0.1 0.012 15.5 0.1 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CAR21064.1 - 0.058 13.0 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like PWWP PF00855.17 CAR21065.1 - 8.2e-14 51.8 0.0 1.8e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 PWWP domain MFS_1 PF07690.16 CAR21066.1 - 1.8e-31 109.4 28.4 1.8e-31 109.4 28.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_36 PF17167.4 CAR21066.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Type_III_YscG PF09477.10 CAR21067.1 - 0.09 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Ribosomal_S19e PF01090.19 CAR21069.1 - 7.6e-55 184.4 0.0 8.4e-55 184.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18 PF17135.4 CAR21070.1 - 4.3e-87 290.4 2.7 4.8e-87 290.2 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e NAC PF01849.18 CAR21070.1 - 0.02 14.9 0.0 0.27 11.2 0.0 2.3 2 1 0 2 2 2 0 NAC domain Ribosomal_L27A PF00828.19 CAR21070.1 - 0.034 14.8 0.3 0.034 14.8 0.3 2.3 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A MFS_1 PF07690.16 CAR21071.1 - 1.3e-26 93.3 37.4 1.3e-26 93.3 37.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.24 CAR21071.1 - 3.2 7.5 7.0 3 7.6 0.8 2.6 2 1 0 2 2 2 0 Fatty acid desaturase Redoxin PF08534.10 CAR21072.1 - 1.5e-29 102.6 0.2 1.7e-29 102.4 0.2 1.1 1 0 0 1 1 1 1 Redoxin PCI PF01399.27 CAR21073.1 - 0.00028 21.4 0.2 0.00071 20.1 0.2 1.8 1 0 0 1 1 1 1 PCI domain YL1 PF05764.13 CAR21073.1 - 0.023 14.8 2.5 0.034 14.3 2.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Trypan_PARP PF05887.11 CAR21073.1 - 0.031 14.3 1.1 0.056 13.4 1.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Hairy_orange PF07527.13 CAR21073.1 - 0.064 13.5 0.5 3.5 7.9 0.1 3.2 3 0 0 3 3 3 0 Hairy Orange PIR PF00399.19 CAR21074.1 - 1.1e-06 28.0 6.5 1.1e-06 28.0 6.5 3.6 2 0 0 2 2 2 1 Yeast PIR protein repeat Med13_C PF06333.12 CAR21074.1 - 0.84 8.8 12.7 1.2 8.4 12.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Spc7_N PF15402.6 CAR21074.1 - 2.2 6.4 14.3 2.7 6.1 14.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GCR1_C PF12550.8 CAR21075.1 - 1e-22 80.2 0.1 1.9e-22 79.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes ALIX_LYPXL_bnd PF13949.6 CAR21075.1 - 0.0084 15.4 0.0 0.0084 15.4 0.0 1.9 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV FadA PF09403.10 CAR21075.1 - 0.18 12.3 2.3 1.7 9.1 0.1 2.4 2 0 0 2 2 2 0 Adhesion protein FadA Fib_alpha PF08702.10 CAR21075.1 - 0.27 11.4 0.2 0.27 11.4 0.2 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 CAR21075.1 - 0.59 10.8 4.2 2.7 8.7 0.8 2.8 2 1 0 2 2 2 0 SlyX NTP_transf_2 PF01909.23 CAR21076.1 - 2.4e-20 72.6 0.7 5.8e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CAR21076.1 - 1.3e-16 60.5 0.0 4.3e-16 58.9 0.0 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 CAR21076.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase RF-1 PF00472.20 CAR21077.1 - 2.5e-20 72.5 0.4 3.1e-20 72.3 0.4 1.1 1 0 0 1 1 1 1 RF-1 domain Pkinase PF00069.25 CAR21078.1 - 5.1e-65 219.4 0.9 4.2e-64 216.5 0.9 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21078.1 - 2.1e-51 174.7 0.0 3.1e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CAR21078.1 - 1.8e-23 82.6 0.2 4.2e-23 81.4 0.2 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CAR21078.1 - 5.8e-11 42.8 0.0 1.2e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CAR21078.1 - 5.2e-06 25.5 0.0 5.2e-06 25.5 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CAR21078.1 - 7.3e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR21078.1 - 0.057 13.3 0.4 0.26 11.2 0.3 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DCB PF16213.5 CAR21079.1 - 6.3e-49 166.0 3.1 6.3e-49 166.0 3.1 3.8 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CAR21079.1 - 4.9e-36 124.0 2.9 4.9e-36 124.0 2.9 5.7 6 1 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CAR21079.1 - 9.2e-20 70.4 5.4 2.5e-13 49.1 0.1 3.8 3 1 0 4 4 4 3 C-terminal region of Mon2 protein Ipi1_N PF12333.8 CAR21079.1 - 0.036 14.7 0.1 20 5.8 0.0 3.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation Pet20 PF08692.10 CAR21080.1 - 3.8e-24 85.8 0.0 2.3e-23 83.3 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial protein Pet20 PalH PF08733.10 CAR21081.1 - 1.2e-86 290.7 12.6 1.5e-86 290.5 12.6 1.0 1 0 0 1 1 1 1 PalH/RIM21 DUF4362 PF14275.6 CAR21081.1 - 0.0037 17.5 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4362) RabGAP-TBC PF00566.18 CAR21082.1 - 1.5e-45 155.5 0.7 2.6e-45 154.7 0.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DpnI_C PF17726.1 CAR21082.1 - 0.21 11.7 2.8 1.4 9.1 0.0 3.0 3 0 0 3 3 3 0 Dam-replacing HTH domain Get5_bdg PF16843.5 CAR21083.1 - 2.3e-25 87.8 0.5 4.1e-25 87.0 0.5 1.4 1 0 0 1 1 1 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein Get5_C PF18514.1 CAR21083.1 - 6.7e-20 70.5 0.6 1.6e-19 69.3 0.6 1.7 1 0 0 1 1 1 1 Get5 C-terminal domain ubiquitin PF00240.23 CAR21083.1 - 6.1e-07 29.1 1.8 1.3e-06 28.1 1.8 1.6 1 0 0 1 1 1 1 Ubiquitin family Blt1 PF12754.7 CAR21083.1 - 8.8e-05 22.9 0.3 0.00016 22.0 0.2 1.4 1 1 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD_2 PF13881.6 CAR21083.1 - 0.00013 22.0 0.1 0.00022 21.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Pox_MCEL PF03291.16 CAR21083.1 - 0.021 13.9 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Erf4 PF10256.9 CAR21084.1 - 1.2e-33 115.7 0.1 1.6e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TruB_N PF01509.18 CAR21085.1 - 8.6e-40 136.5 0.3 2.5e-38 131.8 0.0 2.5 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CAR21085.1 - 0.00015 21.8 0.7 0.0014 18.7 0.0 2.5 1 1 1 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Mid1 PF12929.7 CAR21086.1 - 2.5e-125 419.1 10.8 2.9e-125 418.8 10.8 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CAR21086.1 - 0.0022 18.6 5.1 0.1 13.2 5.1 2.6 1 1 0 1 1 1 1 Fz domain Big_5 PF13205.6 CAR21086.1 - 0.19 12.4 2.9 0.24 12.1 0.2 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain AAA PF00004.29 CAR21087.1 - 5.5e-17 62.4 0.0 8.9e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CAR21087.1 - 2.4e-16 59.9 0.0 2.2e-12 47.1 0.1 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CAR21087.1 - 2.7e-14 53.4 0.0 7.6e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 CAR21087.1 - 1.2e-07 31.9 0.1 3.2e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 AAA C-terminal domain Rad17 PF03215.15 CAR21087.1 - 2.4e-07 30.9 0.0 1.4e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CAR21087.1 - 8.2e-07 29.6 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR21087.1 - 2.6e-06 27.3 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 CAR21087.1 - 4.5e-06 26.6 0.5 9.3e-06 25.5 0.2 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CAR21087.1 - 6.7e-05 22.9 0.1 0.00015 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR21087.1 - 0.00014 21.7 0.0 0.00071 19.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CAR21087.1 - 0.00014 21.2 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CAR21087.1 - 0.00015 22.1 2.1 0.19 12.0 0.1 2.8 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.13 CAR21087.1 - 0.00016 21.0 0.0 0.00022 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CAR21087.1 - 0.00028 20.9 0.1 0.0016 18.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CAR21087.1 - 0.00031 20.6 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR21087.1 - 0.00038 21.0 0.0 0.00097 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CAR21087.1 - 0.00045 20.0 0.0 0.00073 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CAR21087.1 - 0.00049 20.2 0.0 0.14 12.1 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 CAR21087.1 - 0.00075 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CAR21087.1 - 0.0015 18.1 0.0 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 CAR21087.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CAR21087.1 - 0.0034 17.2 0.0 0.0055 16.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 CAR21087.1 - 0.0041 16.9 0.1 0.021 14.6 0.0 1.9 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CAR21087.1 - 0.0053 17.1 0.3 0.52 10.6 0.0 2.7 2 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CAR21087.1 - 0.012 15.1 0.0 0.076 12.4 0.0 2.0 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 CAR21087.1 - 0.012 15.0 0.1 0.28 10.5 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein AAA_25 PF13481.6 CAR21087.1 - 0.026 14.1 0.0 0.39 10.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain PIF1 PF05970.14 CAR21087.1 - 0.034 13.3 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase RNA_helicase PF00910.22 CAR21087.1 - 0.034 14.5 0.0 0.061 13.7 0.0 1.6 1 1 0 1 1 1 0 RNA helicase SNF2_N PF00176.23 CAR21087.1 - 0.037 12.7 0.0 0.055 12.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain MutS_III PF05192.18 CAR21087.1 - 0.069 13.4 0.3 0.17 12.1 0.3 1.6 1 1 0 1 1 1 0 MutS domain III AAA_28 PF13521.6 CAR21087.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CAR21087.1 - 0.11 12.0 0.0 9.8 5.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CAR21087.1 - 0.21 11.7 0.5 0.72 10.0 0.5 2.1 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 CAR21088.1 - 3.4e-11 42.7 46.7 3.5e-07 29.5 22.6 3.6 1 1 3 4 4 4 2 Major Facilitator Superfamily Cyclin_N PF00134.23 CAR21089.1 - 2.6e-19 69.2 0.0 3.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CAR21089.1 - 4.9e-06 27.0 0.0 6.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Apolipoprotein PF01442.18 CAR21091.1 - 0.38 10.6 24.8 0.86 9.5 25.0 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 CAR21091.1 - 2 9.0 24.7 1e+02 3.6 24.7 2.5 1 1 0 1 1 1 0 YtxH-like protein HisKA_3 PF07730.13 CAR21091.1 - 2.8 8.5 11.1 3.3 8.3 1.2 2.3 1 1 1 2 2 2 0 Histidine kinase Mitofilin PF09731.9 CAR21091.1 - 3.3 6.4 31.1 3.7 6.3 31.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF883 PF05957.13 CAR21091.1 - 4.7 7.9 22.6 6.8 7.4 12.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) WTX PF09422.10 CAR21091.1 - 5.3 6.0 18.2 5.7 5.9 18.2 1.0 1 0 0 1 1 1 0 WTX protein RR_TM4-6 PF06459.12 CAR21091.1 - 6.4 6.5 21.0 8.4 6.1 21.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ERM PF00769.19 CAR21091.1 - 8.3 6.1 26.7 9.3 6.0 26.7 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Rcd1 PF04078.13 CAR21092.1 - 1.5e-112 375.1 4.2 1.8e-112 374.8 4.2 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 CAR21092.1 - 0.63 10.0 9.6 0.89 9.5 9.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CAR21092.1 - 5.4 6.6 12.9 8.2 6.0 12.9 1.2 1 0 0 1 1 1 0 Spt20 family Adaptin_N PF01602.20 CAR21093.1 - 1.4e-109 367.0 11.7 1.8e-109 366.7 11.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CAR21093.1 - 2.6e-46 157.5 5.0 7.8e-46 155.9 5.0 1.9 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CAR21093.1 - 1.2e-29 102.8 0.0 3.9e-29 101.1 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CAR21093.1 - 1.7e-13 50.8 0.5 9.4e-07 29.1 0.0 4.6 3 2 2 5 5 5 2 HEAT repeats Cnd1 PF12717.7 CAR21093.1 - 1.4e-06 28.5 9.6 0.0087 16.1 0.1 4.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAR21093.1 - 0.00073 19.6 5.4 37 5.0 0.0 6.4 7 0 0 7 7 7 0 HEAT repeat PLN_propep PF16485.5 CAR21093.1 - 0.004 16.8 0.0 0.0088 15.7 0.0 1.6 1 0 0 1 1 1 1 Protealysin propeptide ATPase PF06745.13 CAR21093.1 - 0.012 15.0 0.6 0.036 13.4 0.1 1.9 2 0 0 2 2 2 0 KaiC PAH PF02671.21 CAR21093.1 - 0.071 13.3 1.3 5.3 7.3 0.3 3.4 2 0 0 2 2 2 0 Paired amphipathic helix repeat HEAT_EZ PF13513.6 CAR21093.1 - 3.3 8.3 4.7 23 5.7 0.3 4.2 4 1 1 5 5 5 0 HEAT-like repeat RRM_1 PF00076.22 CAR21094.1 - 5.4e-14 51.8 0.2 4.4e-06 26.4 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR21094.1 - 0.0052 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 CAR21094.1 - 0.03 14.2 0.1 0.78 9.6 0.0 2.5 3 0 0 3 3 3 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 CAR21094.1 - 0.033 14.3 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 FIST PF08495.10 CAR21094.1 - 0.17 11.9 0.0 0.99 9.4 0.0 1.9 2 0 0 2 2 2 0 FIST N domain DUF3340 PF11818.8 CAR21094.1 - 5.3 7.2 19.4 8.2 6.6 3.2 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) YchF-GTPase_C PF06071.13 CAR21095.1 - 1.9e-36 124.1 1.1 3.5e-36 123.2 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CAR21095.1 - 4.4e-17 62.2 0.0 2.8e-16 59.6 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 CAR21095.1 - 0.00021 21.3 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CAR21095.1 - 0.0062 16.1 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B Cupin_2 PF07883.11 CAR21095.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain SCO1-SenC PF02630.14 CAR21096.1 - 7.3e-48 161.9 0.0 1e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CAR21096.1 - 0.00088 19.2 0.0 0.0023 17.8 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Chitin_synth_1 PF01644.17 CAR21097.1 - 4.1e-71 238.2 0.5 6.9e-71 237.5 0.5 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CAR21097.1 - 3.4e-26 92.0 2.7 1.4e-18 66.8 0.0 2.8 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 CAR21097.1 - 6.4e-20 70.9 0.1 1.7e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 CAR21097.1 - 8.2e-07 29.1 0.5 8.2e-07 29.1 0.5 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CAR21097.1 - 3.3e-06 27.2 0.0 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Peptidase_M20 PF01546.28 CAR21098.1 - 1.4e-32 113.1 0.0 2.7e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR21098.1 - 8.2e-07 28.9 0.0 4.4e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR21098.1 - 1.3e-05 25.0 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Chitin_synth_2 PF03142.15 CAR21099.1 - 3.3e-281 933.5 0.1 3.3e-281 933.5 0.1 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CAR21099.1 - 2.5e-14 53.7 0.6 8.8e-14 51.9 0.6 2.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CAR21099.1 - 2e-12 47.5 0.0 1.3e-09 38.3 0.0 2.6 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CAR21099.1 - 5.7e-05 22.7 0.0 0.00049 19.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CAR21099.1 - 0.003 17.4 0.0 0.088 12.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Macro PF01661.21 CAR21100.1 - 1.1e-24 86.8 0.0 1.5e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Macro domain CBP_BcsO PF17037.5 CAR21100.1 - 0.028 14.6 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO ABC2_membrane PF01061.24 CAR21101.1 - 1.5e-66 223.8 57.4 4.6e-40 137.3 11.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR21101.1 - 1.3e-38 132.6 0.0 5.7e-19 69.0 0.0 3.0 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CAR21101.1 - 3.2e-34 116.7 14.3 1.6e-31 108.0 0.1 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CAR21101.1 - 1.3e-07 31.0 5.8 1.3e-07 31.0 5.8 4.3 3 1 1 4 4 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CAR21101.1 - 8.8e-06 25.7 0.0 0.00032 20.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 CAR21101.1 - 1.7e-05 25.4 0.7 6.2e-05 23.5 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 CAR21101.1 - 3.6e-05 23.7 0.0 0.041 13.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CAR21101.1 - 0.00018 22.0 0.0 0.006 17.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CAR21101.1 - 0.00033 21.2 0.0 0.0091 16.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAR21101.1 - 0.0011 19.1 0.1 0.14 12.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CAR21101.1 - 0.0011 19.3 0.0 0.019 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CAR21101.1 - 0.0018 17.7 0.0 1.2 8.5 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CAR21101.1 - 0.0072 15.9 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CAR21101.1 - 0.0081 15.8 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CAR21101.1 - 0.012 15.4 0.2 0.23 11.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CAR21101.1 - 0.014 15.9 1.4 0.48 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CAR21101.1 - 0.05 13.3 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CAR21101.1 - 0.061 12.6 0.2 0.22 10.8 0.1 1.9 2 0 0 2 2 2 0 Septin AAA_28 PF13521.6 CAR21101.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR21101.1 - 0.12 12.3 0.3 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 CAR21101.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.0 4 0 0 4 4 3 0 Dynamin family GalKase_gal_bdg PF10509.9 CAR21102.1 - 7.4e-20 70.2 0.0 1.6e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CAR21102.1 - 1.1e-17 64.1 0.0 2.7e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CAR21102.1 - 6.6e-15 55.1 1.0 1.4e-14 54.0 1.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1748 PF08520.10 CAR21102.1 - 0.023 14.6 0.1 0.062 13.2 0.1 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) NiFe_hyd_SSU_C PF14720.6 CAR21102.1 - 0.17 12.2 0.7 0.96 9.9 0.7 2.1 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Aldose_epim PF01263.20 CAR21103.1 - 8.3e-58 196.1 0.0 1.1e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.21 CAR21103.1 - 1.2e-52 178.8 0.0 2e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR21103.1 - 2.6e-51 175.0 0.0 3.7e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CAR21103.1 - 1.1e-15 57.5 0.0 6.9e-14 51.7 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CAR21103.1 - 3.7e-14 52.4 0.0 1.3e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CAR21103.1 - 8.4e-12 44.8 0.0 1.3e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 CAR21103.1 - 6.6e-09 35.9 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 CAR21103.1 - 2.7e-08 33.5 0.0 4.9e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CAR21103.1 - 4.8e-05 22.7 0.0 0.00093 18.4 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 CAR21103.1 - 0.0018 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GalP_UDP_tr_C PF02744.17 CAR21104.1 - 1.2e-66 223.5 0.1 2.2e-66 222.7 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 CAR21104.1 - 3.2e-64 216.8 0.0 4.9e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 CAR21104.1 - 0.0019 18.9 0.0 0.032 15.0 0.0 2.3 2 0 0 2 2 2 1 HIT domain Peptidase_M24 PF00557.24 CAR21105.1 - 8.8e-59 198.7 0.0 1.1e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CAR21105.1 - 3.7e-24 84.8 0.0 7.5e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain UCH PF00443.29 CAR21106.1 - 4.8e-12 45.9 0.2 1.2e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CAR21106.1 - 1.1e-08 35.3 0.1 2.1e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUF5644 PF18712.1 CAR21106.1 - 0.045 13.8 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5644) JAB PF01398.21 CAR21107.1 - 1.4e-32 112.2 0.3 1.4e-32 112.2 0.3 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CAR21107.1 - 1.1e-10 41.9 2.0 2.3e-10 40.9 1.2 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CAR21107.1 - 2.7e-07 30.4 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CAR21107.1 - 0.0072 16.4 0.8 0.028 14.5 0.7 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) PGM_PMM_II PF02879.16 CAR21107.1 - 0.11 13.2 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PPI_Ypi1 PF07491.11 CAR21108.1 - 2.3e-20 72.2 19.1 2.3e-20 72.2 19.1 2.4 2 1 0 2 2 2 1 Protein phosphatase inhibitor YL1 PF05764.13 CAR21108.1 - 0.028 14.6 15.2 0.033 14.3 15.2 1.3 1 1 0 1 1 1 0 YL1 nuclear protein Pacs-1 PF10254.9 CAR21108.1 - 0.14 11.1 5.0 0.19 10.6 5.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein SR-25 PF10500.9 CAR21108.1 - 0.99 9.0 29.0 3.1 7.3 29.0 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mem_trans PF03547.18 CAR21108.1 - 7.4 4.8 5.4 8.9 4.6 5.4 1.1 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.14 CAR21108.1 - 9.6 4.4 14.2 9.6 4.4 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nic96 PF04097.14 CAR21109.1 - 3.1e-203 676.7 9.1 4e-203 676.3 9.1 1.1 1 0 0 1 1 1 1 Nup93/Nic96 SWIRM-assoc_1 PF16495.5 CAR21110.1 - 0.023 14.6 5.6 0.023 14.6 5.6 1.8 2 0 0 2 2 2 0 SWIRM-associated region 1 Hat1_N PF10394.9 CAR21111.1 - 6.3e-42 143.5 0.4 9.9e-42 142.9 0.4 1.3 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CAR21111.1 - 0.00042 20.5 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR21111.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EAP30 PF04157.16 CAR21112.1 - 1.9e-54 184.5 0.0 2.2e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family SHE3 PF17078.5 CAR21112.1 - 0.11 12.2 1.2 0.9 9.2 0.1 2.2 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 PseudoU_synth_1 PF01416.20 CAR21113.1 - 1.1e-30 106.3 0.0 5.3e-27 94.4 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase CHD5 PF04420.14 CAR21113.1 - 0.2 11.5 1.8 0.46 10.3 1.8 1.5 1 0 0 1 1 1 0 CHD5-like protein DEAD PF00270.29 CAR21114.1 - 6.8e-40 136.7 0.0 1.3e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR21114.1 - 1e-23 83.8 1.0 1.9e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR21114.1 - 4.4e-17 62.1 0.3 1e-16 60.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 CAR21114.1 - 0.0046 16.2 0.0 0.0046 16.2 0.0 2.2 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase DUF4746 PF15928.5 CAR21114.1 - 0.37 10.2 7.0 0.54 9.6 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ThiF PF00899.21 CAR21115.1 - 3.4e-06 26.6 0.0 0.0083 15.5 0.0 2.4 2 1 0 2 2 2 2 ThiF family Pil1 PF13805.6 CAR21116.1 - 5.4e-122 406.4 0.2 6.6e-122 406.1 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.10 CAR21116.1 - 0.0034 17.5 0.2 0.13 12.4 0.2 2.8 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Nop10p PF04135.12 CAR21116.1 - 0.31 11.1 1.9 20 5.3 0.1 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family PPR_2 PF13041.6 CAR21117.1 - 9e-15 54.6 0.7 7.8e-07 29.2 0.0 5.2 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 CAR21117.1 - 7e-06 26.0 0.1 0.0068 16.5 0.0 3.4 3 0 0 3 3 3 2 Pentatricopeptide repeat domain Thioredoxin_14 PF18402.1 CAR21117.1 - 0.00045 20.3 1.6 0.023 14.7 0.2 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain PPR PF01535.20 CAR21117.1 - 0.042 14.1 0.9 37 4.9 0.0 4.7 5 0 0 5 5 5 0 PPR repeat ydhR PF08803.11 CAR21117.1 - 0.092 12.7 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR NPC1_N PF16414.5 CAR21118.1 - 2.9e-81 272.6 12.1 5.6e-81 271.7 12.1 1.5 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CAR21118.1 - 6.6e-54 183.3 21.6 7e-51 173.3 21.6 2.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 CAR21118.1 - 2e-39 134.9 26.0 2.3e-39 134.7 8.0 2.6 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 CAR21118.1 - 0.00019 19.3 16.0 0.00028 18.7 14.1 1.9 2 0 0 2 2 2 1 AcrB/AcrD/AcrF family zf-TFIIIC PF12660.7 CAR21119.1 - 1.1e-12 47.7 0.0 1.8e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 CAR21119.1 - 0.00012 22.3 0.6 0.13 12.6 0.3 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain UDPGT PF00201.18 CAR21119.1 - 0.16 10.7 0.2 0.29 9.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Helicase_C_2 PF13307.6 CAR21120.1 - 6.4e-50 169.6 0.1 1.9e-49 168.1 0.1 1.9 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CAR21120.1 - 1.3e-44 151.9 0.0 3.2e-44 150.7 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CAR21120.1 - 1.8e-05 24.8 0.8 0.013 15.5 0.0 2.8 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR21120.1 - 0.0027 17.5 0.1 0.15 11.8 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 CAR21120.1 - 0.009 15.5 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_22 PF13401.6 CAR21120.1 - 0.058 13.7 2.7 1.7 9.0 0.3 3.1 2 1 0 2 2 2 0 AAA domain SieB PF14163.6 CAR21120.1 - 0.064 12.7 1.0 0.86 9.1 0.0 2.7 3 0 0 3 3 3 0 Super-infection exclusion protein B Intron_maturas2 PF01348.21 CAR21121.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II intron maturase Ribosomal_S16 PF00886.19 CAR21123.1 - 6.2e-25 87.0 0.1 8e-25 86.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.12 CAR21124.1 - 4.6e-69 232.2 0.9 3.1e-66 222.9 0.0 4.5 5 0 0 5 5 5 1 NUC173 domain HEAT PF02985.22 CAR21124.1 - 1.3e-05 25.1 0.9 0.074 13.4 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Ipi1_N PF12333.8 CAR21124.1 - 0.023 15.3 0.1 3 8.5 0.0 3.7 2 1 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation tRNA_synt_1c_R1 PF04558.15 CAR21124.1 - 0.1 12.6 4.7 2.3 8.2 1.1 3.0 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Bromo_TP PF07524.13 CAR21125.1 - 6.1e-05 22.9 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Clat_adaptor_s PF01217.20 CAR21126.1 - 1.1e-16 61.1 0.2 1.6e-16 60.5 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DASH_Dad4 PF08650.10 CAR21126.1 - 0.034 14.1 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad4 OrfB_IS605 PF01385.19 CAR21126.1 - 0.14 12.4 0.2 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Probable transposase NFACT-C PF11923.8 CAR21127.1 - 5.2e-28 97.1 1.6 5.2e-28 97.1 1.6 3.8 3 1 1 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 CAR21127.1 - 1.4e-20 73.6 0.1 1.4e-20 73.6 0.1 3.5 3 1 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CAR21127.1 - 2e-18 67.1 0.1 9.3e-18 64.9 0.0 2.3 2 0 0 2 2 2 1 NFACT protein RNA binding domain Peroxidase_2 PF01328.17 CAR21127.1 - 8 6.9 9.1 1.2 9.7 3.1 2.3 2 0 0 2 2 2 0 Peroxidase, family 2 SIR2 PF02146.17 CAR21128.1 - 1.1e-55 188.3 0.0 1.4e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1788 PF08747.11 CAR21128.1 - 0.15 12.1 0.3 3.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Peptidase_C48 PF02902.19 CAR21129.1 - 1.8e-36 126.0 0.1 4e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain VTC PF09359.10 CAR21130.1 - 1e-90 303.9 0.0 2.2e-90 302.8 0.0 1.6 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CAR21130.1 - 7.8e-12 45.8 20.8 0.00041 20.4 1.2 4.5 4 1 1 5 5 5 4 SPX domain DUF202 PF02656.15 CAR21130.1 - 8.2e-11 42.2 4.0 8.2e-11 42.2 4.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) NCE101 PF11654.8 CAR21130.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 DUF2975 PF11188.8 CAR21130.1 - 1 9.3 3.1 1.8 8.4 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Ras PF00071.22 CAR21131.1 - 4.5e-63 211.7 0.3 5.4e-63 211.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR21131.1 - 4e-37 127.1 0.3 5.7e-37 126.6 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR21131.1 - 3.6e-19 68.9 0.1 4.3e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CAR21131.1 - 9.6e-08 31.7 0.1 1.3e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CAR21131.1 - 3.4e-07 29.8 0.1 4.1e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR21131.1 - 2.2e-06 27.7 0.1 3.5e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR21131.1 - 1.3e-05 25.2 0.3 0.074 12.9 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CAR21131.1 - 4.2e-05 23.2 0.3 0.00039 20.0 0.2 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAR21131.1 - 0.00039 20.0 0.1 0.0037 16.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 CAR21131.1 - 0.0056 16.2 0.1 0.014 14.9 0.1 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region MCM PF00493.23 CAR21131.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain AAA PF00004.29 CAR21131.1 - 0.016 15.7 0.0 0.86 10.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CAR21131.1 - 0.041 13.6 0.1 0.13 12.0 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CAR21131.1 - 0.042 14.1 0.1 0.24 11.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 CAR21131.1 - 0.057 12.6 0.7 1.1 8.3 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 CAR21131.1 - 0.062 13.7 0.1 0.1 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CAR21131.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein BLM10_mid PF16507.5 CAR21132.1 - 1.2e-166 555.4 8.6 2.6e-166 554.3 8.6 1.6 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 CAR21132.1 - 1.3e-32 111.9 0.0 4.2e-32 110.3 0.0 2.0 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 CAR21132.1 - 1.4e-25 89.1 0.0 3.8e-25 87.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) SMC_N PF02463.19 CAR21133.1 - 7.8e-55 185.7 34.5 3.7e-54 183.5 34.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR21133.1 - 1.6e-25 89.7 0.1 6.1e-25 87.8 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CAR21133.1 - 5.2e-12 46.2 8.3 6.9e-07 29.4 0.0 3.5 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR21133.1 - 5.3e-09 35.7 0.1 1.3e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CAR21133.1 - 1.7e-07 31.3 24.3 1.7e-07 31.3 24.3 4.4 2 2 2 4 4 4 1 AAA ATPase domain FUSC PF04632.12 CAR21133.1 - 0.0032 16.1 2.7 0.0032 16.1 2.7 3.9 4 1 1 5 5 5 1 Fusaric acid resistance protein family AAA_33 PF13671.6 CAR21133.1 - 0.064 13.4 0.3 1.2 9.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain VWA_2 PF13519.6 CAR21133.1 - 2.3 8.9 6.8 2.1 9.1 0.1 4.2 3 1 0 3 3 3 0 von Willebrand factor type A domain WD40 PF00400.32 CAR21135.1 - 3.3e-35 119.5 21.1 4e-07 30.6 1.6 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat CDC4_D PF16856.5 CAR21135.1 - 1.7e-20 72.6 0.5 3.3e-20 71.7 0.5 1.5 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box-like PF12937.7 CAR21135.1 - 2.6e-09 36.8 0.1 5.6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR21135.1 - 6.7e-08 32.2 1.1 1.5e-07 31.1 1.1 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CAR21135.1 - 8.5e-06 26.0 0.1 0.15 12.4 0.1 4.5 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR21135.1 - 0.014 14.1 4.7 1 7.9 0.1 4.5 3 2 3 6 6 6 0 Nucleoporin Nup120/160 JmjC PF02373.22 CAR21135.1 - 0.037 14.5 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase PRANC PF09372.10 CAR21135.1 - 0.044 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 PRANC domain STE PF02200.16 CAR21135.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 STE like transcription factor Kelch_6 PF13964.6 CAR21135.1 - 0.5 10.7 3.3 13 6.2 0.1 3.6 4 0 0 4 4 4 0 Kelch motif DAO PF01266.24 CAR21136.1 - 2.5e-22 79.9 0.0 3.3e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CAR21136.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 CAR21136.1 - 0.17 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding WW PF00397.26 CAR21137.1 - 4.9e-09 36.1 0.3 1.3e-08 34.7 0.3 1.8 1 0 0 1 1 1 1 WW domain HSP9_HSP12 PF04119.12 CAR21140.1 - 1.2e-26 92.8 9.7 1.4e-25 89.4 5.6 2.2 2 0 0 2 2 2 2 Heat shock protein 9/12 DUF357 PF04010.13 CAR21140.1 - 0.058 13.5 1.2 0.67 10.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF357) YtxH PF12732.7 CAR21140.1 - 0.67 10.5 8.7 2.1e+02 2.6 8.7 2.3 1 1 0 1 1 1 0 YtxH-like protein DnaJ_C PF01556.18 CAR21141.1 - 3.3e-24 85.7 0.0 4.6e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR21141.1 - 8.9e-24 83.4 2.7 1.6e-23 82.6 2.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR21141.1 - 8.1e-12 45.3 17.8 1.4e-11 44.6 17.8 1.4 1 0 0 1 1 1 1 DnaJ central domain FecR PF04773.13 CAR21141.1 - 0.074 13.7 0.0 0.25 12.0 0.0 1.8 2 0 0 2 2 2 0 FecR protein HypA PF01155.19 CAR21141.1 - 0.17 11.9 6.7 0.34 11.0 1.7 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CAR21141.1 - 0.21 11.6 6.9 0.61 10.1 0.7 2.3 2 0 0 2 2 2 0 Double zinc ribbon Coatomer_WDAD PF04053.14 CAR21141.1 - 0.23 10.4 0.1 0.32 10.0 0.1 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Sporozoite_P67 PF05642.11 CAR21141.1 - 0.42 8.6 7.3 0.57 8.2 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RseC_MucC PF04246.12 CAR21141.1 - 1.3 9.0 2.9 0.86 9.6 0.7 1.9 2 1 0 2 2 1 0 Positive regulator of sigma(E), RseC/MucC Cytochrom_c3_2 PF14537.6 CAR21141.1 - 2.2 8.8 4.9 2.8 8.5 3.7 1.8 1 1 0 1 1 1 0 Cytochrome c3 Anti-TRAP PF15777.5 CAR21141.1 - 7.1 6.7 19.1 2.3 8.3 7.6 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2781 PF10914.8 CAR21142.1 - 7.7e-42 143.2 8.2 8.7e-42 143.0 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) ACPS PF01648.20 CAR21142.1 - 0.16 12.1 0.4 0.2 11.8 0.4 1.3 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily SBE2 PF17076.5 CAR21143.1 - 0.011 14.0 0.7 0.015 13.5 0.7 1.2 1 0 0 1 1 1 0 SBE2, cell-wall formation MRP-S34 PF16053.5 CAR21143.1 - 0.07 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S34 ARTD15_N PF18084.1 CAR21143.1 - 0.13 12.5 0.3 1.2 9.5 0.1 2.4 3 0 0 3 3 3 0 ARTD15 N-terminal domain Acetyltransf_1 PF00583.25 CAR21144.1 - 5.1e-15 55.7 0.1 6.4e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAR21144.1 - 9.8e-10 38.7 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAR21144.1 - 2.9e-08 33.7 0.0 3.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR21144.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM PF01423.22 CAR21145.1 - 1.3e-19 69.7 0.1 1.4e-19 69.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain Pyr_redox_2 PF07992.14 CAR21146.1 - 1.3e-68 231.4 4.3 1.8e-68 230.9 4.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAR21146.1 - 4.7e-44 149.1 0.1 1.5e-43 147.5 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAR21146.1 - 2e-19 69.9 7.5 3.5e-18 65.9 0.5 3.7 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR21146.1 - 1.1e-10 41.6 1.0 3e-05 24.2 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CAR21146.1 - 8.2e-09 35.1 2.7 4.2e-06 26.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR21146.1 - 1.5e-08 34.5 0.4 1.5e-08 34.5 0.4 2.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.22 CAR21146.1 - 3.9e-08 32.8 7.9 6.1e-08 32.1 3.1 2.4 1 1 1 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CAR21146.1 - 1.4e-06 27.6 1.4 1.4e-06 27.6 1.4 2.6 2 1 1 3 3 3 1 FAD binding domain K_oxygenase PF13434.6 CAR21146.1 - 1.6e-05 24.3 0.3 0.19 10.9 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CAR21146.1 - 1.7e-05 24.3 6.5 0.092 12.0 0.2 3.8 2 1 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 CAR21146.1 - 0.00022 20.6 0.8 0.098 11.9 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CAR21146.1 - 0.0018 17.1 11.4 0.031 13.0 0.6 4.2 3 2 1 4 4 4 1 HI0933-like protein Thi4 PF01946.17 CAR21146.1 - 0.0034 16.7 2.7 0.0036 16.6 0.1 2.2 2 1 0 2 2 2 1 Thi4 family THF_DHG_CYH_C PF02882.19 CAR21146.1 - 0.015 14.6 0.3 0.1 11.9 0.0 2.5 4 0 0 4 4 4 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain E3_binding PF02817.17 CAR21146.1 - 0.03 14.7 0.8 2.1 8.8 0.0 3.5 3 0 0 3 3 3 0 e3 binding domain DAO PF01266.24 CAR21146.1 - 0.045 13.3 20.9 0.93 9.0 0.0 4.5 2 2 1 4 4 4 0 FAD dependent oxidoreductase DUF1194 PF06707.11 CAR21146.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) 3HCDH_N PF02737.18 CAR21146.1 - 0.11 12.4 3.0 0.12 12.2 0.1 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PTS_IIB PF02302.17 CAR21146.1 - 0.22 12.2 3.5 17 6.2 0.1 3.9 2 1 1 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit GATA PF00320.27 CAR21147.1 - 6.8e-17 60.8 3.3 1.2e-16 60.0 3.3 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CAR21147.1 - 1.8e-06 27.7 0.4 5.5e-06 26.1 0.4 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 CAR21147.1 - 0.11 12.1 0.4 0.2 11.2 0.4 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Fcf2 PF08698.11 CAR21148.1 - 1.9e-35 121.1 3.9 1.9e-35 121.1 3.9 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing vMSA PF00695.19 CAR21148.1 - 0.21 10.7 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Spt5_N PF11942.8 CAR21148.1 - 1 10.4 6.0 0.78 10.8 1.3 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal tRNA-synt_2d PF01409.20 CAR21150.1 - 7.3e-88 294.2 0.0 1.1e-87 293.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CAR21150.1 - 2.6e-13 50.1 1.2 3.2e-13 49.7 0.2 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 CAR21150.1 - 1e-11 44.6 2.9 1e-11 44.6 2.9 2.0 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 CAR21150.1 - 1.4e-07 31.2 0.0 2.3e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CAR21150.1 - 1.2e-05 24.6 0.1 0.00081 18.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CAR21150.1 - 4.5e-05 23.5 0.0 8.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_45 PF14947.6 CAR21150.1 - 0.017 15.1 2.4 0.71 9.9 0.3 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix PaaX PF07848.12 CAR21150.1 - 0.049 13.8 0.0 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 PaaX-like protein GCR1_C PF12550.8 CAR21153.1 - 3.1e-12 46.6 1.3 4.8e-11 42.8 1.3 2.3 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF3835 PF12927.7 CAR21154.1 - 1.5e-20 73.8 17.6 6.2e-20 71.8 0.2 5.8 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) Prefoldin PF02996.17 CAR21154.1 - 1.3e-10 41.2 3.9 2.4e-10 40.4 2.6 2.2 2 0 0 2 2 2 1 Prefoldin subunit XhlA PF10779.9 CAR21154.1 - 0.072 13.3 0.8 0.3 11.3 0.8 2.1 1 0 0 1 1 1 0 Haemolysin XhlA EPL1 PF10513.9 CAR21155.1 - 2.7e-23 83.1 4.1 2.7e-23 83.1 4.1 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like Activator_LAG-3 PF11498.8 CAR21155.1 - 0.25 10.3 24.1 0.056 12.4 18.1 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PGAP1 PF07819.13 CAR21156.1 - 7.4e-94 313.8 0.0 1.2e-93 313.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2670 PF10875.8 CAR21156.1 - 0.0049 17.0 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2670) LCAT PF02450.15 CAR21156.1 - 0.0055 15.9 0.0 0.0086 15.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 CAR21156.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAR21156.1 - 0.017 14.8 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR21156.1 - 0.028 15.0 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 CAR21156.1 - 0.028 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CAR21156.1 - 0.029 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 CAR21156.1 - 0.15 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CAR21156.1 - 0.17 11.7 0.0 0.74 9.7 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) STE2 PF02116.15 CAR21157.1 - 4.9e-78 262.3 28.8 6.3e-78 261.9 28.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DENN PF02141.21 CAR21157.1 - 0.17 11.8 4.5 0.29 11.1 2.5 2.3 3 0 0 3 3 3 0 DENN (AEX-3) domain AA_permease_2 PF13520.6 CAR21158.1 - 8.4e-85 285.1 42.7 1.1e-84 284.8 42.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR21158.1 - 5.4e-17 61.5 41.4 7.3e-17 61.1 41.4 1.1 1 0 0 1 1 1 1 Amino acid permease SIR2 PF02146.17 CAR21159.1 - 5.3e-32 111.2 0.0 5.4e-10 39.5 0.0 3.1 3 0 0 3 3 3 3 Sir2 family Bromodomain PF00439.25 CAR21160.1 - 8.5e-32 109.1 4.2 2.1e-17 62.9 0.3 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 CAR21160.1 - 3.8e-25 88.1 0.1 9.7e-25 86.8 0.1 1.8 1 0 0 1 1 1 1 BAH domain RXT2_N PF08595.11 CAR21160.1 - 0.58 10.2 13.1 2.5 8.1 2.7 3.2 3 0 0 3 3 3 0 RXT2-like, N-terminal SDA1 PF05285.12 CAR21160.1 - 0.98 8.8 14.1 1.7 8.0 3.1 2.3 2 0 0 2 2 2 0 SDA1 CENP-B_dimeris PF09026.10 CAR21160.1 - 1.3 9.5 16.9 0.33 11.3 1.1 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 CAR21160.1 - 9.4 5.9 18.7 1 9.0 2.0 2.8 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Lyase_1 PF00206.20 CAR21161.1 - 2.3e-22 79.8 0.0 4.1e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CAR21161.1 - 3.3e-18 66.0 0.0 1.9e-17 63.6 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 CAR21161.1 - 0.1 12.3 1.0 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Folliculin PF11704.8 CAR21162.1 - 2e-39 135.4 0.1 3.8e-39 134.5 0.1 1.4 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Mtc PF03820.17 CAR21162.1 - 0.05 12.6 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier DUF2321 PF10083.9 CAR21162.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) SWIRM PF04433.17 CAR21163.1 - 9.6e-28 96.4 0.2 2.9e-27 94.8 0.2 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.17 CAR21163.1 - 7.8e-14 51.2 3.2 1.3e-13 50.6 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM-assoc_1 PF16495.5 CAR21163.1 - 6.8e-11 42.0 7.1 6.8e-11 42.0 7.1 2.7 3 0 0 3 3 3 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CAR21163.1 - 7.2e-09 35.7 0.1 1.7e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR21163.1 - 5.3e-06 26.6 0.2 4.6e-05 23.6 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain THOC7 PF05615.13 CAR21163.1 - 3.1e-05 24.3 3.1 3.1e-05 24.3 3.1 2.4 2 0 0 2 2 2 1 Tho complex subunit 7 zf-CCHC_2 PF13696.6 CAR21163.1 - 0.0082 15.9 2.4 0.62 9.9 0.1 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-UBR PF02207.20 CAR21163.1 - 0.011 15.8 1.2 0.021 15.0 1.2 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF760 PF05542.11 CAR21163.1 - 0.095 13.1 0.1 1.8 8.9 0.1 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF760) SNF2_N PF00176.23 CAR21164.1 - 4.6e-64 216.3 0.3 9.5e-64 215.3 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR21164.1 - 3.9e-26 91.6 2.4 5e-23 81.6 0.0 3.4 4 0 0 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 CAR21164.1 - 5.6e-08 33.0 0.0 5.6e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CAR21164.1 - 6.1e-07 28.9 0.0 6.1e-07 28.9 0.0 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CAR21164.1 - 7.9e-06 25.8 0.0 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Guanylate_cyc_2 PF09778.9 CAR21164.1 - 0.081 12.3 0.1 0.22 10.9 0.1 1.6 1 0 0 1 1 1 0 Guanylylate cyclase Rep_4 PF05797.11 CAR21164.1 - 0.23 10.6 4.9 0.52 9.4 4.9 1.6 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) zf-C4H2 PF10146.9 CAR21164.1 - 0.79 10.0 10.5 2 8.7 10.5 1.6 1 0 0 1 1 1 0 Zinc finger-containing protein cNMP_binding PF00027.29 CAR21165.1 - 9.2e-45 150.6 0.1 1.2e-21 76.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CAR21165.1 - 3.2e-09 36.3 4.5 1.1e-08 34.6 4.5 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.11 CAR21165.1 - 0.0066 16.1 2.7 1.3 8.7 0.4 2.6 2 0 0 2 2 2 2 Cupin domain Erg28 PF03694.13 CAR21166.1 - 3.4e-43 146.5 1.6 4.8e-43 146.0 1.6 1.2 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.16 CAR21166.1 - 0.017 15.2 2.0 0.021 14.8 0.2 1.9 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange UPF0239 PF06783.11 CAR21166.1 - 0.05 13.8 0.2 0.072 13.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) TMEM239 PF15841.5 CAR21166.1 - 0.058 13.3 0.6 0.12 12.3 0.2 1.6 1 1 1 2 2 2 0 Transmembrane protein 239 family Fzo_mitofusin PF04799.13 CAR21166.1 - 0.064 12.8 0.2 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 fzo-like conserved region Aldo_ket_red PF00248.21 CAR21167.1 - 2.3e-47 161.6 0.1 1.3e-45 155.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 CAR21168.1 - 6e-07 29.5 9.3 1.2e-06 28.5 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR21168.1 - 0.093 11.7 2.3 0.16 11.0 0.3 2.4 2 1 0 2 2 2 0 Fungal specific transcription factor domain F_actin_cap_B PF01115.17 CAR21169.1 - 7e-91 304.1 0.0 8e-91 303.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.25 CAR21170.1 - 2.5e-59 200.8 7.3 1.3e-52 178.8 0.9 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21170.1 - 2.8e-18 66.1 1.8 8.1e-14 51.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAR21170.1 - 1.1e-05 25.6 0.0 6.1e-05 23.1 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR21170.1 - 0.0075 15.1 0.0 0.019 13.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR21170.1 - 0.019 14.3 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CAR21170.1 - 0.019 14.5 0.1 0.042 13.4 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase bZIP_1 PF00170.21 CAR21172.1 - 1e-15 57.5 8.4 1.5e-15 57.0 8.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CAR21172.1 - 1e-08 35.1 7.0 1.8e-08 34.3 7.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CAR21172.1 - 0.0088 16.5 6.6 0.019 15.5 6.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor FemAB PF02388.16 CAR21172.1 - 0.015 14.2 0.4 0.02 13.8 0.4 1.1 1 0 0 1 1 1 0 FemAB family DUF4200 PF13863.6 CAR21172.1 - 0.25 11.7 6.4 0.41 11.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) GED PF02212.18 CAR21174.1 - 0.0035 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain HRG PF16954.5 CAR21174.1 - 0.52 10.7 0.1 0.52 10.7 0.1 3.1 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Not3 PF04065.15 CAR21175.1 - 5.5e-80 268.1 26.0 5.5e-80 268.1 26.0 2.5 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CAR21175.1 - 8.4e-21 74.4 0.0 2.4e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CAR21175.1 - 0.045 14.1 0.8 0.045 14.1 0.8 3.5 4 0 0 4 4 4 0 Syntaxin-like protein TauD PF02668.16 CAR21176.1 - 1.9e-40 139.4 0.1 2.4e-40 139.0 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ASXH PF13919.6 CAR21176.1 - 0.097 12.7 0.0 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Asx homology domain AAA PF00004.29 CAR21177.1 - 7.1e-40 136.5 0.0 1.3e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CAR21177.1 - 7.9e-09 35.4 0.7 1.9e-06 27.8 0.0 3.2 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CAR21177.1 - 6.1e-07 29.1 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CAR21177.1 - 1.5e-05 24.8 0.0 7.4e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAR21177.1 - 3.9e-05 23.9 0.2 0.0024 18.2 0.1 2.9 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CAR21177.1 - 6.8e-05 23.0 0.0 0.00016 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAR21177.1 - 0.00043 20.3 0.0 0.0019 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CAR21177.1 - 0.00051 19.3 0.0 0.00091 18.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 CAR21177.1 - 0.00053 20.4 0.1 0.0043 17.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CAR21177.1 - 0.00093 19.2 0.0 0.027 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR21177.1 - 0.0011 19.5 0.2 0.0099 16.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CAR21177.1 - 0.0046 16.4 0.1 0.0098 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CAR21177.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TPPII_N PF12583.8 CAR21177.1 - 0.0061 17.1 0.2 0.0061 17.1 0.2 2.8 3 1 0 3 3 1 1 Tripeptidyl peptidase II N terminal AAA_25 PF13481.6 CAR21177.1 - 0.0076 15.8 1.5 0.33 10.5 0.1 3.0 1 1 2 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CAR21177.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 CAR21177.1 - 0.018 15.0 0.1 12 5.8 0.0 3.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CAR21177.1 - 0.029 14.5 0.0 0.078 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR21177.1 - 0.042 13.8 0.0 0.38 10.7 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 CAR21177.1 - 0.077 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAR21177.1 - 0.098 12.2 0.5 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Chromo PF00385.24 CAR21177.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PhoH PF02562.16 CAR21177.1 - 0.18 11.2 0.0 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DnaJ-X PF14308.6 CAR21179.1 - 3.1e-63 213.0 9.8 3.1e-63 213.0 9.8 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CAR21179.1 - 1.3e-26 92.5 1.1 4.2e-26 90.8 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain PAP_central PF04928.17 CAR21179.1 - 0.055 12.4 0.8 0.068 12.1 0.8 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain Apq12 PF12716.7 CAR21180.1 - 1.3e-05 25.0 6.2 1.3e-05 25.0 6.2 1.8 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Complex1_LYR PF05347.15 CAR21181.1 - 6.1e-17 61.4 0.2 7.5e-17 61.1 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CAR21181.1 - 0.0018 18.8 0.0 0.0021 18.6 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 CAR21181.1 - 0.0033 18.2 0.1 0.0038 18.0 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Ofd1_CTDD PF10637.9 CAR21182.1 - 6.4e-95 317.3 1.5 2.4e-93 312.2 1.6 2.3 2 0 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CAR21182.1 - 1.3e-26 93.0 0.1 1.7e-25 89.5 0.1 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CAR21182.1 - 6e-14 52.7 0.2 2.2e-13 50.9 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CAR21182.1 - 0.061 13.8 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily BAR_2 PF10455.9 CAR21183.1 - 7e-83 278.1 13.9 7e-83 278.1 13.9 2.3 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CAR21183.1 - 1.9e-18 67.0 14.5 1.9e-18 67.0 14.5 2.8 1 1 1 2 2 2 1 BAR domain BAR_3 PF16746.5 CAR21183.1 - 3.6e-06 26.8 4.9 3.6e-06 26.8 4.9 2.3 2 1 0 2 2 2 1 BAR domain of APPL family TACC_C PF05010.14 CAR21183.1 - 9.1e-05 22.3 2.9 9.1e-05 22.3 2.9 2.4 2 1 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Glyco_transf_5 PF08323.11 CAR21183.1 - 0.089 12.5 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Lectin_N PF03954.14 CAR21183.1 - 0.26 11.1 10.0 0.33 10.7 3.8 2.7 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Plasmid_parti PF01672.16 CAR21183.1 - 1 10.0 4.4 1.5 9.5 1.6 2.5 2 1 0 2 2 2 0 Putative plasmid partition protein Macscav_rec PF03523.13 CAR21183.1 - 2 8.4 5.9 2.1 8.3 1.0 2.8 1 1 1 2 2 2 0 Macrophage scavenger receptor GAT PF03127.14 CAR21183.1 - 2.6 8.4 7.3 0.98 9.8 0.4 3.5 3 2 1 4 4 4 0 GAT domain FUSC PF04632.12 CAR21183.1 - 5.6 5.4 7.8 4.7 5.6 0.1 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family Tup_N PF08581.10 CAR21183.1 - 6 7.3 12.1 1.6 9.1 0.3 4.5 2 2 3 5 5 5 0 Tup N-terminal BCDHK_Adom3 PF10436.9 CAR21184.1 - 8.4e-24 84.2 0.4 1.4e-23 83.6 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CAR21184.1 - 7.9e-15 55.3 0.0 1.7e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CAR21184.1 - 4.6e-05 23.3 0.1 0.0001 22.1 0.0 1.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S18 PF01084.20 CAR21185.1 - 5.8e-21 74.5 0.0 1.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 PHD PF00628.29 CAR21186.1 - 9.4e-07 28.6 1.9 1.7e-06 27.8 1.9 1.4 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.6 CAR21186.1 - 6.5e-05 22.8 0.1 0.0019 17.9 0.0 2.5 1 1 0 1 1 1 1 Cupin-like domain JHD PF17811.1 CAR21186.1 - 0.00053 20.5 0.2 0.0019 18.7 0.2 1.9 1 1 0 1 1 1 1 Jumonji helical domain Cupin_4 PF08007.12 CAR21186.1 - 0.0033 17.0 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein zf-HC5HC2H PF13771.6 CAR21186.1 - 0.0035 17.6 1.1 0.0075 16.5 1.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain C1_1 PF00130.22 CAR21186.1 - 0.0085 16.0 1.5 0.017 15.0 1.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) JmjC PF02373.22 CAR21186.1 - 0.017 15.6 0.0 0.074 13.5 0.0 2.1 1 1 0 1 1 1 0 JmjC domain, hydroxylase Cupin_1 PF00190.22 CAR21186.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Cupin zf-HC5HC2H_2 PF13832.6 CAR21186.1 - 0.047 13.9 1.2 0.089 13.0 1.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zf_RING PF16744.5 CAR21186.1 - 0.12 12.5 1.5 0.21 11.7 1.5 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger NAD_binding_1 PF00175.21 CAR21187.1 - 1.3e-30 106.3 0.0 1.9e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAR21187.1 - 6.3e-29 100.2 0.0 1e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAR21187.1 - 0.0001 22.4 0.0 0.092 12.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CAR21187.1 - 0.2 11.9 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain AA_kinase PF00696.28 CAR21188.1 - 3.8e-41 141.3 0.0 1.7e-40 139.1 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 CAR21188.1 - 1.6e-13 50.1 0.2 1.5e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CAR21188.1 - 2.7e-09 36.7 1.5 1.1e-06 28.3 0.3 2.5 2 0 0 2 2 2 2 ACT domain Flt3_lig PF02947.14 CAR21188.1 - 0.13 12.4 0.8 0.36 11.0 0.2 2.0 2 0 0 2 2 2 0 flt3 ligand Cyt-b5 PF00173.28 CAR21189.1 - 2.6e-21 75.5 0.0 3.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RIP PF00161.19 CAR21189.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosome inactivating protein MHB PF16525.5 CAR21189.1 - 0.15 12.3 0.1 0.67 10.3 0.0 2.0 2 0 0 2 2 2 0 Haemophore, haem-binding ArfGap PF01412.18 CAR21190.1 - 8.9e-36 122.5 0.6 1.3e-35 121.9 0.6 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Mito_carr PF00153.27 CAR21191.1 - 7.1e-43 144.5 2.9 5.9e-14 51.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBM_21 PF03370.13 CAR21192.1 - 8.4e-28 96.8 0.0 1.4e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CAR21192.1 - 3.5e-09 37.1 0.5 3.3e-08 34.0 0.5 2.4 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) WD40 PF00400.32 CAR21193.1 - 6.1e-35 118.7 33.5 4.6e-06 27.3 0.6 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 CAR21193.1 - 5.6e-15 55.0 0.4 1.2e-14 53.9 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR21193.1 - 8.5e-12 44.7 0.2 1.8e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CAR21193.1 - 1.5e-11 43.7 6.0 0.011 14.4 0.0 5.8 4 1 2 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CAR21193.1 - 7.3e-08 32.6 0.2 0.23 11.8 0.0 5.3 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR21193.1 - 0.00062 19.2 0.1 0.71 9.1 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain F-box_4 PF15966.5 CAR21193.1 - 0.0039 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 F-box BBS2_Mid PF14783.6 CAR21193.1 - 0.0052 16.8 0.0 2.5 8.2 0.0 3.7 2 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 CAR21193.1 - 0.12 12.3 0.1 2.2 8.1 0.0 2.7 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nore1-SARAH PF16517.5 CAR21193.1 - 0.13 12.2 0.5 0.29 11.1 0.5 1.6 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain HisG PF01634.18 CAR21194.1 - 2.7e-53 180.2 0.1 3.6e-53 179.8 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CAR21194.1 - 3.4e-28 97.6 0.0 6e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain EXS PF03124.14 CAR21195.1 - 9.7e-85 284.8 27.3 1.4e-84 284.3 27.3 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CAR21195.1 - 4.7e-37 128.8 6.7 5e-23 82.6 1.0 2.9 1 1 1 2 2 2 2 SPX domain Cytochrom_B_C PF00032.17 CAR21195.1 - 0.21 11.9 6.9 2.4 8.5 0.9 2.7 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD PhoLip_ATPase_C PF16212.5 CAR21196.1 - 6.5e-53 180.0 10.8 6.5e-53 180.0 10.8 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR21196.1 - 1.9e-17 62.7 2.3 4.1e-17 61.6 2.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CAR21196.1 - 7.1e-12 45.2 0.0 7.1e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAR21196.1 - 7.7e-12 45.9 0.3 0.00011 22.6 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR21196.1 - 1e-09 38.4 0.0 9.3e-09 35.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CAR21196.1 - 0.004 16.9 0.1 0.0097 15.7 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CCDC85 PF10226.9 CAR21196.1 - 0.075 12.7 0.4 0.16 11.6 0.4 1.5 1 0 0 1 1 1 0 CCDC85 family Ribosomal_L34e PF01199.18 CAR21197.1 - 5.5e-41 138.8 3.3 5.5e-41 138.8 3.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e Ribonuc_L-PSP PF01042.21 CAR21198.1 - 4.1e-41 139.8 0.8 5e-41 139.5 0.8 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP tRNA_synt_2f PF02092.17 CAR21198.1 - 0.033 13.1 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit PET117 PF15786.5 CAR21199.1 - 7.5e-32 109.4 2.7 1.1e-31 108.9 2.7 1.3 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF4294 PF14127.6 CAR21199.1 - 0.025 14.5 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) Ctr PF04145.15 CAR21199.1 - 0.027 15.1 0.1 0.03 14.9 0.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Cyclin PF08613.11 CAR21200.1 - 5.4e-48 163.4 1.6 1.5e-47 162.0 1.6 1.8 1 1 0 1 1 1 1 Cyclin Transp_cyt_pur PF02133.15 CAR21201.1 - 8.3e-84 281.9 38.6 9.6e-84 281.7 38.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4191 PF13829.6 CAR21201.1 - 0.68 9.2 1.7 5.1 6.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Steroid_dh PF02544.16 CAR21202.1 - 8.9e-16 58.2 4.3 1e-15 58.1 2.9 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 CAR21202.1 - 2.9e-06 27.6 3.4 8e-05 23.0 0.4 2.6 2 1 0 2 2 2 2 Phospholipid methyltransferase DUF3043 PF11241.8 CAR21202.1 - 0.16 12.0 0.5 11 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF998 PF06197.13 CAR21202.1 - 2 8.0 8.2 0.095 12.3 0.7 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF998) ketoacyl-synt PF00109.26 CAR21203.1 - 4.1e-57 193.6 0.1 6e-57 193.1 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CAR21203.1 - 5.3e-33 113.5 1.5 9.5e-33 112.7 1.5 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CAR21203.1 - 0.018 14.4 0.2 0.05 12.9 0.0 1.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain HAD_2 PF13419.6 CAR21204.1 - 1.2e-15 58.0 0.0 1.6e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR21204.1 - 1.5e-09 38.4 0.0 2.4e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR21204.1 - 0.00088 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CAR21205.1 - 2.1e-15 57.3 0.0 2.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR21205.1 - 4.2e-11 43.5 0.0 9.6e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR21205.1 - 7.6e-05 23.2 0.0 0.0001 22.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR21205.1 - 0.049 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Tho1_MOS11_C PF18592.1 CAR21206.1 - 5.3e-24 83.8 0.3 9.7e-24 82.9 0.3 1.4 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 CAR21206.1 - 4e-11 42.4 0.0 6.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 SAP domain Trypan_PARP PF05887.11 CAR21206.1 - 0.0007 19.6 20.1 0.0014 18.6 20.1 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) HeH PF12949.7 CAR21206.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Vhr1 PF04001.13 CAR21208.1 - 8.9e-45 150.9 3.4 2e-44 149.8 3.4 1.6 1 0 0 1 1 1 1 Transcription factor Vhr1 ICL PF00463.21 CAR21209.1 - 3.5e-274 910.2 1.0 4e-274 910.0 1.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CAR21209.1 - 5.2e-09 35.9 0.0 1.1e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RGI1 PF10843.8 CAR21210.1 - 2.1e-34 118.9 10.8 3.7e-34 118.1 10.8 1.3 1 1 0 1 1 1 1 Respiratory growth induced protein 1 DUF5100 PF17029.5 CAR21210.1 - 0.0071 16.2 2.5 0.013 15.4 2.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5100) zf-RING_4 PF14570.6 CAR21211.1 - 3.6e-20 71.5 12.9 7.8e-20 70.4 12.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 CAR21211.1 - 1.4e-06 28.0 0.2 8.7e-05 22.3 0.2 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 CAR21211.1 - 1.6e-06 27.8 8.1 1.6e-06 27.8 8.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CAR21211.1 - 4.7e-06 26.6 4.0 1.4e-05 25.1 4.0 1.8 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) SET_assoc PF11767.8 CAR21211.1 - 0.0021 17.6 0.0 0.0092 15.6 0.0 2.1 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 CAR21211.1 - 0.0023 17.7 8.3 0.069 13.0 8.9 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAR21211.1 - 0.003 17.8 9.9 0.003 17.8 9.9 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAR21211.1 - 0.0039 17.0 11.2 0.009 15.9 11.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CAR21211.1 - 0.0043 16.5 3.0 0.0043 16.5 3.0 2.1 3 0 0 3 3 3 1 Rtf2 RING-finger PocR PF10114.9 CAR21211.1 - 0.088 12.6 3.3 0.19 11.5 1.3 2.2 2 0 0 2 2 2 0 Sensory domain found in PocR zf-C3H1 PF10650.9 CAR21211.1 - 0.18 11.6 0.1 0.18 11.6 0.1 2.1 2 0 0 2 2 2 0 Putative zinc-finger domain zf-RING_5 PF14634.6 CAR21211.1 - 0.58 10.2 8.9 1.4 8.9 8.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DUF4810 PF16068.5 CAR21211.1 - 0.87 10.2 8.3 4.4 7.9 5.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4810) zf-RING_UBOX PF13445.6 CAR21211.1 - 1.4 9.0 9.1 2.2 8.4 8.2 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR21211.1 - 2.2 8.2 9.8 5.1 7.0 9.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U1snRNP70_N PF12220.8 CAR21212.1 - 2.3e-21 76.2 0.3 4.7e-21 75.2 0.3 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CAR21212.1 - 1.3e-14 53.8 0.0 2.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR21212.1 - 9.2e-06 25.7 0.4 2.9e-05 24.1 0.1 2.0 2 1 0 2 2 2 1 RNA recognition motif NAT PF04768.13 CAR21213.1 - 5.4e-53 179.1 0.0 1.3e-52 177.9 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 CAR21213.1 - 3.5e-31 108.2 0.0 7e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 CAR21213.1 - 1.4e-24 87.0 0.0 2.8e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.18 CAR21213.1 - 1.9e-09 37.8 0.1 9.3e-09 35.6 0.0 2.2 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 CAR21213.1 - 0.066 13.3 0.0 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.14 CAR21214.1 - 7.8e-48 162.7 0.0 8.7e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CAR21214.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family Ran_BP1 PF00638.18 CAR21215.1 - 2.6e-33 114.9 0.0 5.5e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain Methyltransf_31 PF13847.6 CAR21216.1 - 2.8e-28 98.7 0.0 3.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR21216.1 - 1.1e-08 35.7 0.0 3.4e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR21216.1 - 7.3e-07 29.9 0.0 1.2e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR21216.1 - 2.2e-06 28.2 0.0 3.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CAR21216.1 - 3.3e-06 27.2 0.0 3.9e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAR21216.1 - 0.00023 20.8 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CAR21216.1 - 0.00037 20.4 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CAR21216.1 - 0.0013 18.3 0.1 0.0032 17.0 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 AdoMet_MTase PF07757.13 CAR21216.1 - 0.0016 18.8 0.0 0.0039 17.5 0.0 1.6 2 0 0 2 2 2 1 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 CAR21216.1 - 0.0094 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.17 CAR21216.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 CAR21216.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain Fis1_TPR_C PF14853.6 CAR21217.1 - 5.1e-25 87.3 0.2 7.7e-25 86.7 0.2 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CAR21217.1 - 3.1e-16 58.7 0.1 5.9e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_14 PF13428.6 CAR21217.1 - 0.13 13.1 0.0 0.45 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.15 CAR21218.1 - 5.2e-184 612.6 0.0 6.7e-184 612.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CAR21218.1 - 2.4e-23 81.9 0.0 6e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CAR21218.1 - 4.9e-16 59.1 0.0 1.2e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain LCCL PF03815.19 CAR21219.1 - 5e-11 42.6 0.1 1.1e-10 41.5 0.1 1.6 1 0 0 1 1 1 1 LCCL domain Sec6 PF06046.13 CAR21220.1 - 9.6e-176 585.5 9.3 9.6e-176 585.5 9.3 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 TFB6 PF17110.5 CAR21220.1 - 0.029 14.1 1.5 9.5 5.9 0.0 3.4 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH Vps53_N PF04100.12 CAR21220.1 - 0.97 8.3 21.8 0.08 11.9 3.8 3.5 4 0 0 4 4 4 0 Vps53-like, N-terminal MutS_III PF05192.18 CAR21220.1 - 1.6 8.9 11.1 2.3e+02 1.9 11.1 2.7 1 1 0 1 1 1 0 MutS domain III Tctex-1 PF03645.13 CAR21221.1 - 0.00063 19.9 0.0 0.00083 19.6 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 CAR21222.1 - 2.1e-15 56.9 4.4 3.1e-15 56.3 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 CAR21222.1 - 0.13 12.2 3.8 0.38 10.6 3.8 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5337) FixQ PF05545.11 CAR21222.1 - 9.2 6.3 7.2 1.9 8.5 0.3 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Aldedh PF00171.22 CAR21223.1 - 1.4e-183 610.6 0.0 1.6e-183 610.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S24e PF01282.19 CAR21224.1 - 9.1e-35 118.5 0.1 1.5e-34 117.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Yos1 PF08571.10 CAR21225.1 - 6.2e-32 109.7 1.7 6.9e-32 109.6 1.7 1.0 1 0 0 1 1 1 1 Yos1-like Y_phosphatase PF00102.27 CAR21226.1 - 4.4e-47 160.6 0.2 8.2e-47 159.7 0.2 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CAR21226.1 - 1.1e-06 29.1 0.0 4.2e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 CAR21226.1 - 0.0095 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CAR21226.1 - 0.027 14.4 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family MAM33 PF02330.16 CAR21227.1 - 3.5e-58 197.0 3.9 4e-58 196.8 3.9 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cons_hypoth95 PF03602.15 CAR21227.1 - 0.0087 15.7 0.3 0.028 14.1 0.1 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 NAD_binding_2 PF03446.15 CAR21227.1 - 0.0094 16.1 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PPR_2 PF13041.6 CAR21228.1 - 6.6e-23 80.7 0.1 1.6e-12 47.4 0.0 2.8 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 CAR21228.1 - 0.00052 20.0 0.1 0.0056 16.7 0.0 2.7 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CAR21228.1 - 0.0015 18.1 0.1 0.66 9.7 0.0 3.3 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 CAR21228.1 - 0.025 13.9 0.1 0.084 12.2 0.1 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP DUF3981 PF13139.6 CAR21228.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) eIF3m_C_helix PF18005.1 CAR21228.1 - 0.14 11.9 0.4 0.39 10.5 0.4 1.8 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix DUF2089 PF09862.9 CAR21229.1 - 0.00065 19.7 0.1 0.002 18.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) TPR_2 PF07719.17 CAR21229.1 - 0.025 14.7 0.4 0.64 10.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat JAKMIP_CC3 PF16034.5 CAR21229.1 - 0.061 13.3 3.2 0.095 12.6 2.6 1.6 1 1 0 1 1 1 0 JAKMIP CC3 domain PikAIV_N PF18605.1 CAR21229.1 - 0.7 9.5 4.2 0.47 10.1 1.9 1.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Peptidase_M24 PF00557.24 CAR21230.1 - 4e-52 177.0 0.0 5.7e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CAR21230.1 - 6.8e-37 125.9 0.0 1.3e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HORMA PF02301.18 CAR21231.1 - 2.1e-61 207.2 0.1 5.9e-61 205.8 0.0 1.8 2 0 0 2 2 2 1 HORMA domain PHD_2 PF13831.6 CAR21231.1 - 0.16 11.5 7.0 0.32 10.6 7.0 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 CAR21231.1 - 8.2 6.4 13.5 20 5.2 13.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 CAR21233.1 - 5.6e-09 36.3 0.0 1.2e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR21233.1 - 0.00061 19.2 0.0 1.1 8.5 0.0 2.9 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family AglB_L1 PF18079.1 CAR21233.1 - 0.17 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain 2-Hacid_dh_C PF02826.19 CAR21234.1 - 5.1e-53 179.1 0.0 9.8e-53 178.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR21234.1 - 4.8e-38 129.8 0.1 6.2e-38 129.5 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 CAR21234.1 - 0.00014 21.6 0.1 0.00085 19.0 0.0 2.3 2 0 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.21 CAR21234.1 - 0.00016 21.8 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 CAR21234.1 - 0.00026 21.2 0.4 0.00063 20.0 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RPN2_C PF18004.1 CAR21235.1 - 4.2e-52 176.3 9.0 7.5e-52 175.5 9.0 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CAR21235.1 - 1.8e-38 129.0 22.5 3e-06 27.4 1.2 8.8 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CAR21235.1 - 4.2e-16 59.1 2.6 8.2e-15 55.0 0.1 3.5 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CAR21235.1 - 1.7e-07 31.6 2.9 0.65 10.6 0.1 4.5 4 0 0 4 4 4 3 HEAT-like repeat HEAT PF02985.22 CAR21235.1 - 2.3e-07 30.5 1.4 0.86 10.0 0.0 4.7 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 CAR21235.1 - 0.048 13.7 5.4 2.5 8.1 0.1 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 CAR21235.1 - 0.16 12.2 0.0 1.6 9.1 0.0 2.8 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 NARP1 PF12569.8 CAR21235.1 - 2 7.2 9.7 4.2 6.2 9.7 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BING4CT PF08149.11 CAR21236.1 - 2.9e-36 123.1 0.0 1.8e-33 114.2 0.0 3.6 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CAR21236.1 - 5.8e-06 27.0 0.0 0.012 16.4 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21236.1 - 7.7e-05 22.9 0.0 6 7.2 0.0 4.8 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DHO_dh PF01180.21 CAR21237.1 - 5e-98 328.0 0.1 5.9e-98 327.7 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CAR21237.1 - 0.0064 15.6 0.0 0.35 9.9 0.0 2.7 2 1 0 2 2 2 1 FMN-dependent dehydrogenase DUF3372 PF11852.8 CAR21237.1 - 0.055 12.9 0.0 0.092 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3372) GET2 PF08690.10 CAR21238.1 - 2.8e-99 332.7 0.2 3.2e-99 332.5 0.2 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 Pex19 PF04614.12 CAR21238.1 - 0.0044 16.8 5.8 0.0059 16.4 5.8 1.2 1 0 0 1 1 1 1 Pex19 protein family DUF4554 PF15091.6 CAR21238.1 - 0.71 8.7 3.5 0.9 8.4 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) DUF1631 PF07793.11 CAR21238.1 - 2.9 6.2 11.1 3.6 5.9 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Coatomer_E PF04733.14 CAR21239.1 - 1.5e-14 54.1 8.7 2.1e-14 53.6 8.7 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 CAR21239.1 - 2.4e-05 24.7 7.7 0.23 12.0 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR21239.1 - 0.023 14.8 8.2 5.8 7.3 0.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Type_III_YscG PF09477.10 CAR21239.1 - 0.055 13.5 0.6 2.6 8.2 0.1 2.8 2 1 0 2 2 2 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_20 PF14561.6 CAR21239.1 - 0.059 13.7 1.9 0.76 10.2 0.1 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR21239.1 - 0.13 12.2 2.0 5.5 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR21239.1 - 0.16 12.9 0.4 14 6.8 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR21239.1 - 0.16 12.2 2.9 13 6.3 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1689 PF07954.11 CAR21240.1 - 5.7e-55 185.8 0.1 7.7e-55 185.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.25 CAR21241.1 - 1.5e-36 126.0 0.0 2.9e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CAR21241.1 - 6.2e-19 67.9 1.2 1.5e-18 66.7 1.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 CAR21241.1 - 5.5e-14 52.0 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CAR21241.1 - 3.1e-11 43.2 0.0 7.8e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 TGS domain Wx5_PLAF3D7 PF09688.10 CAR21241.1 - 3.4 7.7 6.4 4.2 7.4 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) zf-CCHC PF00098.23 CAR21242.1 - 3.1e-10 39.6 46.7 2.6e-05 24.1 3.4 5.4 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 CAR21242.1 - 0.0032 17.2 1.6 0.0032 17.2 1.6 5.0 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.6 CAR21242.1 - 1.9 8.3 31.5 1.4 8.7 2.6 5.2 4 1 1 5 5 5 0 Zinc knuckle Pmp3 PF01679.17 CAR21243.1 - 6e-21 74.4 4.6 8.2e-21 73.9 4.6 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0029 PF01205.19 CAR21244.1 - 2.6e-31 108.1 0.0 3.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Tnp_22_trimer PF17489.2 CAR21244.1 - 0.058 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 L1 transposable element trimerization domain FAD-oxidase_C PF02913.19 CAR21245.1 - 5.6e-61 206.3 0.0 8.2e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAR21245.1 - 2.4e-37 127.7 0.1 4.5e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HIT PF01230.23 CAR21246.1 - 1.6e-22 80.1 0.1 2.1e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CAR21246.1 - 1.4e-06 28.8 0.0 2.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.29 CAR21247.1 - 9.3e-98 323.8 0.0 7.1e-48 162.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR21247.1 - 8.8e-24 83.1 8.6 2.8e-13 49.4 1.3 3.4 3 1 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 CAR21247.1 - 3.4e-17 62.4 2.7 4.2e-17 62.1 1.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 CAR21247.1 - 5.3e-14 52.7 0.0 1.7e-07 31.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CAR21247.1 - 9e-14 51.5 0.0 1.7e-05 24.7 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR21247.1 - 6.5e-13 49.4 0.1 8.5e-05 23.0 0.0 4.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_33 PF13671.6 CAR21247.1 - 1.4e-11 44.7 0.0 1e-05 25.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CAR21247.1 - 3.2e-11 43.4 0.7 1.7e-05 24.9 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CAR21247.1 - 3.1e-09 36.5 0.0 0.0015 17.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 CAR21247.1 - 6.8e-09 35.4 0.1 1.8e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CAR21247.1 - 4e-08 33.6 3.8 0.045 14.0 0.1 4.4 3 2 1 4 4 3 2 AAA domain Vps4_C PF09336.10 CAR21247.1 - 2.1e-07 30.8 0.4 5.5e-05 23.1 0.0 3.2 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 CAR21247.1 - 2.3e-07 31.1 0.0 0.013 15.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 CAR21247.1 - 3.7e-07 30.2 0.0 0.027 14.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 CAR21247.1 - 4.6e-07 29.4 0.5 0.037 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAR21247.1 - 7.1e-07 29.1 0.1 0.032 14.0 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein ATPase PF06745.13 CAR21247.1 - 2.9e-06 26.8 2.5 0.29 10.4 0.0 3.8 3 1 0 4 4 4 2 KaiC AAA_18 PF13238.6 CAR21247.1 - 3.5e-06 27.6 0.0 0.17 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CAR21247.1 - 4.2e-06 26.6 0.0 0.06 13.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CAR21247.1 - 8.3e-06 26.4 0.1 0.056 14.0 0.0 4.0 3 1 0 3 3 3 1 ABC transporter AAA_7 PF12775.7 CAR21247.1 - 1.5e-05 24.6 0.1 0.07 12.6 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 CAR21247.1 - 3e-05 23.8 0.1 0.35 10.6 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 CAR21247.1 - 3.1e-05 23.9 0.0 0.13 12.1 0.0 3.3 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_28 PF13521.6 CAR21247.1 - 3.4e-05 24.1 0.3 0.57 10.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.17 CAR21247.1 - 3.6e-05 23.0 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CAR21247.1 - 5.7e-05 22.8 6.3 0.36 10.4 0.2 4.2 2 2 2 4 4 4 1 AAA domain PhoH PF02562.16 CAR21247.1 - 8.4e-05 22.1 0.6 0.19 11.2 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.13 CAR21247.1 - 0.00012 21.3 0.0 0.093 11.9 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 CAR21247.1 - 0.00012 22.5 0.4 0.57 10.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_3 PF07726.11 CAR21247.1 - 0.00018 21.4 0.0 0.91 9.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CAR21247.1 - 0.0003 20.8 0.0 0.62 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CAR21247.1 - 0.00034 20.6 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CAR21247.1 - 0.00069 19.0 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CAR21247.1 - 0.00081 19.3 2.3 1.3 8.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 CAR21247.1 - 0.0017 18.3 0.1 2.2 8.1 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 CAR21247.1 - 0.0018 18.0 0.4 2.1 8.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CAR21247.1 - 0.0039 17.1 2.1 2.6 7.9 0.1 3.9 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CAR21247.1 - 0.0042 17.4 1.2 3.7 7.9 0.0 3.4 3 1 1 4 4 2 1 AAA domain Zeta_toxin PF06414.12 CAR21247.1 - 0.0082 15.4 0.2 6 6.1 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin IPT PF01745.16 CAR21247.1 - 0.018 14.4 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.22 CAR21247.1 - 0.027 13.6 0.0 5 6.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Cytidylate_kin PF02224.18 CAR21247.1 - 0.037 13.7 0.0 7.9 6.1 0.0 2.9 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 CAR21247.1 - 0.041 14.0 0.0 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Zot PF05707.12 CAR21247.1 - 0.048 13.3 0.0 4.2 7.0 0.0 3.2 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.14 CAR21247.1 - 0.056 12.7 0.3 2.1 7.5 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain AAA_6 PF12774.7 CAR21247.1 - 0.13 11.2 0.2 6.8 5.6 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region NTPase_1 PF03266.15 CAR21247.1 - 0.18 11.7 4.6 8.2 6.3 0.0 4.4 5 0 0 5 5 4 0 NTPase Cyclin_N PF00134.23 CAR21248.1 - 3.5e-16 59.1 0.1 5e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CAR21248.1 - 2.5e-05 24.7 0.0 4.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin Na_Ca_ex PF01699.24 CAR21249.1 - 7.1e-47 159.1 31.4 3.8e-25 88.6 8.3 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein COE1_DBD PF16422.5 CAR21250.1 - 0.18 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain T3SS_needle_reg PF09025.10 CAR21251.1 - 0.039 13.9 0.1 5.3 7.0 0.0 2.2 2 0 0 2 2 2 0 YopR, type III needle-polymerisation regulator ARS2 PF04959.13 CAR21251.1 - 0.12 12.7 0.8 0.2 12.0 0.8 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 DUF4680 PF15730.5 CAR21251.1 - 0.82 10.0 9.3 5.1 7.4 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) Ribosomal_60s PF00428.19 CAR21252.1 - 1.2e-24 86.7 12.2 1.4e-24 86.5 12.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Glyco_hydro_63 PF03200.16 CAR21254.1 - 4e-07 29.2 14.4 2.3e-06 26.7 0.2 4.8 4 3 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain V-SNARE_C PF12352.8 CAR21255.1 - 6.7e-20 71.1 1.8 6.7e-20 71.1 1.8 2.0 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CAR21255.1 - 7.8e-20 71.0 1.9 7.8e-20 71.0 1.9 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CAR21255.1 - 0.00056 19.8 4.0 0.00056 19.8 0.6 2.4 2 1 1 3 3 3 1 Sec20 Mer2 PF09074.10 CAR21255.1 - 0.0035 17.2 0.7 0.0035 17.2 0.7 1.6 2 0 0 2 2 2 1 Mer2 AIG1 PF04548.16 CAR21255.1 - 0.023 14.0 2.3 2.4 7.4 0.1 2.3 1 1 1 2 2 2 0 AIG1 family Use1 PF09753.9 CAR21255.1 - 0.14 11.8 7.2 2.1 8.0 7.2 2.1 1 1 0 1 1 1 0 Membrane fusion protein Use1 Fusion_gly PF00523.18 CAR21255.1 - 0.15 10.3 0.9 0.26 9.5 0.5 1.6 1 1 0 2 2 2 0 Fusion glycoprotein F0 YqjK PF13997.6 CAR21255.1 - 0.15 12.3 1.2 0.52 10.6 0.1 2.4 2 0 0 2 2 2 0 YqjK-like protein Snapin_Pallidin PF14712.6 CAR21255.1 - 0.63 10.5 8.2 0.36 11.3 3.1 2.5 2 2 0 2 2 2 0 Snapin/Pallidin Nsp1_C PF05064.13 CAR21255.1 - 0.9 9.4 6.9 0.42 10.4 1.5 2.5 2 1 1 3 3 3 0 Nsp1-like C-terminal region Fer2 PF00111.27 CAR21256.1 - 2.6e-14 52.9 0.5 3.4e-14 52.6 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain LysM PF01476.20 CAR21256.1 - 0.087 12.9 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 LysM domain Fer2_4 PF13510.6 CAR21256.1 - 0.27 11.3 1.5 1.3 9.1 1.4 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Microtub_bd PF16796.5 CAR21257.1 - 2.4e-16 60.0 0.0 2.4e-16 60.0 0.0 3.0 3 2 0 3 3 3 1 Microtubule binding DUF2935 PF11155.8 CAR21257.1 - 1.1 9.6 13.0 0.051 13.9 2.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) FliD_C PF07195.12 CAR21257.1 - 1.4 8.2 13.0 0.31 10.4 3.3 3.2 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus SAGA-Tad1 PF12767.7 CAR21258.1 - 1.5e-73 247.4 0.5 1.5e-73 247.4 0.5 1.6 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 CAR21258.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BBP1_N PF15271.6 CAR21259.1 - 7.9e-45 153.4 3.3 7.9e-45 153.4 3.3 2.3 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein BBP1_C PF15272.6 CAR21259.1 - 4.3e-43 147.4 20.1 4.3e-43 147.4 20.1 1.7 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal Pox_A_type_inc PF04508.12 CAR21259.1 - 0.0058 16.4 7.1 0.078 12.9 0.1 3.3 3 1 0 3 3 3 2 Viral A-type inclusion protein repeat DUF445 PF04286.12 CAR21259.1 - 0.006 16.4 4.0 0.0079 16.1 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Syntaxin-6_N PF09177.11 CAR21259.1 - 1.6 9.3 7.8 0.67 10.6 4.4 2.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Occludin_ELL PF07303.13 CAR21259.1 - 4.4 8.1 21.9 9.2 7.1 9.9 2.9 2 1 1 3 3 3 0 Occludin homology domain CLZ PF16526.5 CAR21259.1 - 7.3 7.0 14.1 12 6.4 0.6 3.4 2 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 CAR21259.1 - 8.1 6.3 13.0 0.097 12.5 1.0 3.0 2 1 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 CAR21259.1 - 8.8 5.6 8.4 18 4.5 8.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cyclin_N PF00134.23 CAR21261.1 - 2.9e-41 140.2 0.0 4.6e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Rot1 PF10681.9 CAR21262.1 - 1.2e-94 315.7 0.2 1.4e-94 315.5 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal VHS PF00790.19 CAR21263.1 - 1.3e-38 132.1 0.0 2.6e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 CAR21263.1 - 1.5e-18 66.6 2.9 1.5e-18 66.6 2.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger UIM PF02809.20 CAR21263.1 - 0.004 17.0 12.3 0.0064 16.3 2.7 5.0 6 0 0 6 6 6 2 Ubiquitin interaction motif FYVE_2 PF02318.16 CAR21263.1 - 0.0083 16.3 1.8 0.0083 16.3 1.8 2.2 2 0 0 2 2 2 1 FYVE-type zinc finger GAT PF03127.14 CAR21263.1 - 0.04 14.2 0.4 0.15 12.4 0.4 2.1 1 0 0 1 1 1 0 GAT domain zf-AN1 PF01428.16 CAR21263.1 - 0.078 13.1 7.7 0.22 11.7 7.7 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger SART-1 PF03343.13 CAR21263.1 - 1.7 7.1 15.6 0.019 13.5 8.0 1.5 2 0 0 2 2 2 0 SART-1 family DUF4193 PF13834.6 CAR21263.1 - 4 8.0 7.6 0.31 11.6 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4193) XPA_C PF05181.12 CAR21264.1 - 3.4e-22 78.2 0.1 6.7e-22 77.2 0.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CAR21264.1 - 0.0084 16.1 0.3 0.029 14.4 0.3 1.9 1 0 0 1 1 1 1 XPA protein N-terminal Methyltransf_7 PF03492.15 CAR21264.1 - 0.15 11.3 1.2 0.95 8.6 0.1 2.2 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase SAPS PF04499.15 CAR21264.1 - 10 4.8 8.3 0.38 9.5 2.8 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Autophagy_N PF03986.13 CAR21265.1 - 2.4e-44 150.6 1.2 2.4e-44 150.6 1.2 1.5 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 CAR21265.1 - 1.9e-15 56.0 0.6 3.3e-15 55.3 0.6 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 CAR21265.1 - 5.2e-15 55.8 0.8 1.1e-14 54.8 0.3 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain LCAT PF02450.15 CAR21266.1 - 1.9e-122 409.2 0.1 2.8e-122 408.7 0.1 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 CAR21266.1 - 0.033 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 CAR21266.1 - 0.059 14.0 0.0 0.31 11.6 0.0 2.3 2 1 1 3 3 3 0 Alpha/beta hydrolase family Whi5 PF08528.11 CAR21267.1 - 0.0004 19.9 1.2 0.00063 19.3 1.2 1.3 1 0 0 1 1 1 1 Whi5 like ERG2_Sigma1R PF04622.12 CAR21268.1 - 4.2e-86 287.6 0.2 5.1e-86 287.3 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Med9 PF07544.13 CAR21269.1 - 1.2e-24 86.2 1.6 1.5e-24 85.8 1.6 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 CAR21269.1 - 0.012 15.8 0.5 0.037 14.2 0.4 1.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Retrotran_gag_2 PF14223.6 CAR21269.1 - 0.023 14.4 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TelA PF05816.11 CAR21269.1 - 0.044 12.8 0.1 0.055 12.5 0.1 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) TMPIT PF07851.13 CAR21269.1 - 0.075 12.3 0.5 0.087 12.1 0.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF3515 PF12028.8 CAR21269.1 - 0.093 12.4 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) Antigen_Bd37 PF11641.8 CAR21269.1 - 0.1 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein DUF4226 PF10774.9 CAR21269.1 - 0.12 12.7 1.9 1.2 9.4 0.6 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4226) MerR-DNA-bind PF09278.11 CAR21269.1 - 0.2 12.2 7.3 0.36 11.4 4.4 2.4 1 1 1 2 2 2 0 MerR, DNA binding Porin_3 PF01459.22 CAR21270.1 - 1.5e-86 290.2 0.1 1.8e-86 290.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.7 CAR21271.1 - 1.2e-34 119.3 0.2 2.4e-34 118.3 0.2 1.5 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Band_3_cyto PF07565.13 CAR21271.1 - 4.7 6.9 5.8 7 6.4 5.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PFK PF00365.20 CAR21272.1 - 6.9e-181 599.8 1.8 2.3e-102 342.2 1.1 2.2 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase PF00903.25 CAR21273.1 - 5.7e-36 123.5 0.2 2.8e-20 72.8 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CAR21273.1 - 3e-15 56.4 0.0 7.4e-07 29.4 0.0 3.5 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CAR21273.1 - 9.1e-06 25.6 1.2 0.28 11.1 0.1 4.4 4 1 1 5 5 5 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 CAR21273.1 - 5.3e-05 24.0 0.0 0.061 14.1 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CAR21273.1 - 0.00021 21.4 0.0 0.0035 17.5 0.0 2.5 1 1 1 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.6 CAR21273.1 - 0.00035 20.6 0.0 0.043 13.9 0.0 2.7 2 0 0 2 2 2 1 CppA N-terminal Phage_Treg PF04761.12 CAR21273.1 - 0.095 12.8 0.1 4 7.6 0.0 2.5 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator APS-reductase_C PF12139.8 CAR21273.1 - 0.12 12.6 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Adenosine-5'-phosphosulfate reductase beta subunit DUF1338 PF07063.13 CAR21273.1 - 0.15 11.2 0.0 18 4.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1338) HA2 PF04408.23 CAR21274.1 - 1.5e-17 63.8 0.2 4.9e-17 62.2 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR21274.1 - 8.7e-16 58.1 0.0 1.9e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR21274.1 - 4.6e-15 55.9 0.0 2.1e-14 53.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR21274.1 - 9.3e-07 28.8 0.2 2.3e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR21274.1 - 5.4e-06 26.7 0.1 1.5e-05 25.3 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR21274.1 - 0.00065 20.1 0.2 0.003 17.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR21274.1 - 0.00073 19.3 0.0 0.0022 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CAR21274.1 - 0.0019 17.3 0.0 0.0044 16.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 CAR21274.1 - 0.032 14.2 0.1 0.073 13.0 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 CAR21274.1 - 0.054 14.0 2.9 0.08 13.5 0.0 2.7 3 1 0 3 3 3 0 ABC transporter PhoH PF02562.16 CAR21274.1 - 0.096 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 CAR21274.1 - 0.23 11.5 3.4 1.4 9.0 0.1 3.3 3 1 0 3 3 3 0 AAA domain SRP54 PF00448.22 CAR21274.1 - 0.93 9.1 3.2 0.39 10.3 0.1 2.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain PRK PF00485.18 CAR21275.1 - 1.1e-64 217.8 0.0 1.5e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CAR21275.1 - 1.2e-35 122.9 0.1 1.9e-35 122.2 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Zeta_toxin PF06414.12 CAR21275.1 - 0.00082 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 CAR21275.1 - 0.00097 19.0 0.0 0.0024 17.7 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CAR21275.1 - 0.003 18.1 0.0 0.0069 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAR21275.1 - 0.0078 16.4 0.0 0.028 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 CAR21275.1 - 0.017 14.4 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.6 CAR21275.1 - 0.042 14.3 0.3 0.76 10.2 0.3 2.5 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 CAR21275.1 - 0.097 12.7 0.7 0.24 11.5 0.7 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 CAR21275.1 - 0.14 12.5 0.0 0.64 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SPX PF03105.19 CAR21276.1 - 1.1e-43 150.6 7.0 1.8e-30 107.2 0.4 2.5 2 1 1 3 3 3 2 SPX domain CitMHS PF03600.16 CAR21276.1 - 4.9e-25 88.3 48.0 2.5e-16 59.7 21.4 2.2 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CAR21276.1 - 3.1e-24 85.9 44.6 4.3e-24 85.4 44.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region DUF739 PF05339.11 CAR21276.1 - 0.057 13.6 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF739) PBP1_TM PF14812.6 CAR21276.1 - 0.24 11.8 6.2 0.6 10.5 6.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3245 PF11595.8 CAR21276.1 - 0.48 10.9 6.7 0.056 13.9 1.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) NOA36 PF06524.12 CAR21276.1 - 0.81 8.9 7.6 1.4 8.2 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein DUF373 PF04123.13 CAR21276.1 - 2 7.8 24.1 0.05 13.0 9.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF373) Phage_holin_5_2 PF16079.5 CAR21276.1 - 3.4 8.1 9.5 3.8 7.9 2.2 3.9 1 1 2 3 3 3 0 Phage holin family Hol44, in holin superfamily V DUF4667 PF15700.5 CAR21277.1 - 2.1e-44 152.5 0.0 3.8e-43 148.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4667) DUF1708 PF08101.11 CAR21278.1 - 2.6e-61 208.1 0.2 2.6e-61 208.1 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1708) Dus PF01207.17 CAR21279.1 - 2.4e-54 184.5 0.0 1.4e-53 182.0 0.0 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ACC_central PF08326.12 CAR21280.1 - 2.1e-262 872.6 1.5 2.9e-262 872.2 0.4 1.7 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CAR21280.1 - 2.6e-187 623.4 0.0 3.6e-187 622.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CAR21280.1 - 3.6e-51 173.7 0.0 7.7e-51 172.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CAR21280.1 - 2.2e-29 102.2 0.1 4.7e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 CAR21280.1 - 1.6e-20 72.7 0.1 5.6e-20 71.0 0.1 2.1 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_carb_C PF02785.19 CAR21280.1 - 3.9e-20 72.0 0.0 1.8e-19 69.8 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl_2 PF13533.6 CAR21280.1 - 3.6e-06 26.7 0.1 0.016 15.0 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ABC_tran_CTD PF16326.5 CAR21280.1 - 0.0031 17.7 0.4 0.0097 16.1 0.4 1.9 1 0 0 1 1 1 1 ABC transporter C-terminal domain ATP-grasp_3 PF02655.14 CAR21280.1 - 0.0037 17.3 0.0 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CAR21280.1 - 0.0038 16.8 0.0 0.0093 15.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CAR21280.1 - 0.038 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RnfC_N PF13375.6 CAR21280.1 - 0.059 13.3 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Tim17 PF02466.19 CAR21281.1 - 3.8e-28 98.1 2.9 6.4e-28 97.3 2.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_S8 PF00082.22 CAR21282.1 - 2.4e-29 102.6 1.8 1e-28 100.5 1.8 1.7 1 1 0 1 1 1 1 Subtilase family CENP-B_dimeris PF09026.10 CAR21282.1 - 0.21 12.0 5.4 0.43 11.0 5.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HIG_1_N PF04588.13 CAR21283.1 - 1.8e-06 28.1 0.3 3.2e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Ribosomal_L19 PF01245.20 CAR21284.1 - 1.3e-09 38.0 0.5 2.1e-09 37.3 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 MutS_IV PF05190.18 CAR21284.1 - 0.1 12.9 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 MutS family domain IV WBS_methylT PF12589.8 CAR21285.1 - 2e-13 50.9 6.8 3.8e-13 50.0 6.8 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CAR21285.1 - 1.7e-12 47.8 0.0 3.6e-12 46.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR21285.1 - 1.2e-11 45.1 0.1 5.6e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR21285.1 - 3.5e-06 26.9 0.0 5.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR21285.1 - 3.8e-06 27.6 0.1 1.5e-05 25.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR21285.1 - 0.00026 20.8 0.0 0.00068 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CAR21285.1 - 0.00027 20.8 0.0 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CAR21285.1 - 0.0006 19.2 0.3 0.0077 15.6 0.0 2.5 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 CAR21285.1 - 0.0043 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 CAR21285.1 - 0.0076 15.7 1.0 0.018 14.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 CAR21285.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CAR21285.1 - 0.051 13.6 0.4 0.98 9.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain His_binding PF02098.16 CAR21285.1 - 0.3 11.1 3.2 0.16 12.0 0.9 1.6 2 0 0 2 2 2 0 Tick histamine binding protein MBOAT PF03062.19 CAR21286.1 - 1.1e-75 255.2 42.3 1.5e-75 254.7 42.3 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CAR21286.1 - 0.0017 18.5 6.1 0.0017 18.5 6.1 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family HEPN_AbiA_CTD PF18732.1 CAR21286.1 - 0.041 13.8 1.3 0.11 12.4 1.3 1.8 1 0 0 1 1 1 0 HEPN like, Abia C-terminal domain Peptidase_M76 PF09768.9 CAR21287.1 - 3.2e-72 241.8 1.0 3.9e-72 241.6 1.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Ank_5 PF13857.6 CAR21288.1 - 3e-15 56.1 0.1 5.2e-09 36.2 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR21288.1 - 1.1e-13 51.6 0.0 8.9e-12 45.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR21288.1 - 2.5e-08 34.3 0.6 1.8e-05 25.2 0.1 2.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CAR21288.1 - 5.1e-08 33.0 0.2 0.0011 19.3 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CAR21288.1 - 2.3e-06 27.5 0.0 0.0038 17.6 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat DUF1682 PF07946.14 CAR21289.1 - 5.9e-77 259.0 5.8 6.9e-77 258.8 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) GBP_C PF02841.14 CAR21289.1 - 0.041 13.3 12.3 0.063 12.7 12.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RDV-p3 PF09231.10 CAR21289.1 - 0.062 11.0 0.3 0.11 10.2 0.3 1.3 1 0 0 1 1 1 0 Rice dwarf virus p3 DUF4375 PF14300.6 CAR21289.1 - 0.14 12.5 1.1 0.36 11.1 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Ribosomal_L9_N PF01281.19 CAR21290.1 - 3.2e-05 23.4 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain HTH_1 PF00126.27 CAR21290.1 - 1.1 9.3 3.9 0.42 10.6 1.5 1.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SWIB PF02201.18 CAR21291.1 - 2.2e-07 30.6 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 SWIB/MDM2 domain Thr_synth_N PF14821.6 CAR21292.1 - 5.3e-30 103.5 0.1 1.8e-29 101.7 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 CAR21292.1 - 1.1e-10 41.4 0.0 2.4e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.32 CAR21293.1 - 3.6e-49 163.7 14.2 1.1e-08 35.5 0.1 14.0 14 0 0 14 14 14 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21293.1 - 7e-30 103.2 0.0 0.034 14.4 0.0 10.3 3 2 5 10 10 10 8 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CAR21293.1 - 1.6e-23 83.1 0.0 2.5e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CAR21293.1 - 2.3e-12 46.5 2.6 0.038 12.9 0.0 6.9 4 3 4 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CAR21293.1 - 1.3e-07 31.7 0.9 0.0012 18.8 0.1 4.7 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CAR21293.1 - 6.6e-06 25.0 5.7 0.27 9.8 0.0 4.9 3 2 1 5 5 5 2 Nucleoporin Nup120/160 WD40_3 PF15911.5 CAR21293.1 - 0.0017 18.3 0.0 0.0061 16.5 0.0 2.0 1 0 0 1 1 1 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 CAR21293.1 - 0.0025 17.1 0.1 0.71 9.1 0.0 3.1 3 1 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 CAR21293.1 - 0.0063 15.9 0.5 10 5.3 0.1 4.3 4 1 0 5 5 5 1 WD40-like domain Cytochrom_D1 PF02239.16 CAR21293.1 - 0.0083 14.7 0.2 1.4 7.4 0.0 3.3 4 0 0 4 4 4 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 CAR21293.1 - 0.016 14.8 2.4 0.32 10.5 0.6 2.8 1 1 1 2 2 2 0 PQQ-like domain Nbas_N PF15492.6 CAR21293.1 - 0.034 13.5 0.1 19 4.4 0.0 4.0 3 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 CAR21293.1 - 0.055 12.5 0.0 2 7.4 0.0 3.3 4 1 1 5 5 5 0 VID27 C-terminal WD40-like domain PD40 PF07676.12 CAR21293.1 - 0.061 13.3 2.1 31 4.7 0.0 4.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 CAR21293.1 - 0.078 12.7 3.8 6.2 6.6 0.2 4.2 5 0 0 5 5 4 0 Proteasome subunit A N-terminal signature SDA1 PF05285.12 CAR21293.1 - 8.3 5.7 6.0 12 5.2 6.0 1.2 1 0 0 1 1 1 0 SDA1 MPP6 PF10175.9 CAR21294.1 - 2e-24 86.6 16.8 2.3e-24 86.4 16.8 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Utp14 PF04615.13 CAR21294.1 - 0.0012 17.5 21.8 0.0014 17.3 21.8 1.1 1 0 0 1 1 1 1 Utp14 protein DUF913 PF06025.12 CAR21294.1 - 0.75 8.7 9.3 0.96 8.4 9.3 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 CAR21294.1 - 8 5.7 12.2 1.5 8.1 7.6 1.8 1 1 1 2 2 2 0 NOA36 protein UPF0029 PF01205.19 CAR21295.1 - 3.1e-28 98.2 0.1 7.2e-28 97.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CAR21295.1 - 7.2e-08 32.7 0.1 1.7e-07 31.5 0.1 1.7 1 1 0 1 1 1 1 RWD domain Luteo_coat PF00894.18 CAR21295.1 - 0.089 12.7 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 Luteovirus coat protein Ytp1 PF10355.9 CAR21296.1 - 1.4e-108 362.3 9.1 1.9e-108 361.9 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CAR21296.1 - 4.7e-12 45.6 6.6 5.9e-12 45.3 1.6 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF4133 PF13571.6 CAR21296.1 - 0.47 10.8 2.4 2.7 8.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) FMN_red PF03358.15 CAR21297.1 - 7.9e-29 100.4 0.0 1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CAR21297.1 - 1.6e-05 24.7 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold G10 PF01125.17 CAR21298.1 - 4e-61 205.1 5.7 4.5e-61 204.9 5.7 1.0 1 0 0 1 1 1 1 G10 protein DUF1257 PF06868.11 CAR21298.1 - 0.039 14.2 0.3 0.06 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Forkhead PF00250.18 CAR21299.1 - 2.1e-32 111.2 0.0 3.9e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain PP1_bind PF15276.6 CAR21299.1 - 6.8 7.1 9.3 4.5 7.7 0.4 2.9 2 1 1 3 3 3 0 Protein phosphatase 1 binding zf-C3HC4_2 PF13923.6 CAR21300.1 - 1.4e-11 44.1 15.5 1.4e-11 44.0 9.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR21300.1 - 1.9e-10 40.4 10.3 1.9e-10 40.4 10.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR21300.1 - 1e-08 34.9 10.4 8.8e-08 31.9 6.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR21300.1 - 1.9e-08 34.2 16.8 2.5e-08 33.8 9.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger SAP PF02037.27 CAR21300.1 - 2.6e-07 30.2 0.0 6.1e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 SAP domain Prok-RING_4 PF14447.6 CAR21300.1 - 4.7e-07 29.6 11.9 1.6e-05 24.7 6.7 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAR21300.1 - 6.4e-07 29.2 13.1 5e-06 26.4 8.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CAR21300.1 - 5.1e-06 26.7 15.4 8.1e-06 26.1 9.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CAR21300.1 - 7.6e-06 26.0 10.5 7.6e-06 26.0 10.5 2.7 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CAR21300.1 - 0.00015 21.6 4.9 0.00038 20.3 4.9 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CAR21300.1 - 0.00037 20.7 5.5 0.00037 20.7 5.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 CAR21300.1 - 0.0028 17.8 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain GAGA PF09237.11 CAR21300.1 - 0.012 15.4 1.4 0.39 10.6 0.2 3.0 2 0 0 2 2 2 0 GAGA factor Rad50_zn_hook PF04423.14 CAR21300.1 - 0.023 14.5 3.0 1.9 8.4 0.2 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 CAR21300.1 - 0.084 12.8 4.1 0.72 9.8 0.7 2.9 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-Nse PF11789.8 CAR21300.1 - 0.094 12.5 9.2 0.32 10.8 5.5 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 CAR21300.1 - 0.1 12.4 6.5 0.2 11.5 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 CAR21300.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_10 PF16685.5 CAR21300.1 - 0.88 9.7 6.3 2.1 8.5 6.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 CAR21300.1 - 3.4 7.9 6.2 6.4 7.1 1.4 2.7 3 0 0 3 3 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 CAR21300.1 - 4.7 7.4 7.8 10 6.3 0.0 2.8 2 1 0 2 2 2 0 FYVE zinc finger ANAPC4_WD40 PF12894.7 CAR21301.1 - 1.8e-09 37.7 0.0 1.7e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR21301.1 - 2e-05 25.3 0.1 0.73 10.8 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Phos_pyr_kin PF08543.12 CAR21302.1 - 9.1e-12 44.9 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CAR21302.1 - 0.00081 18.8 0.0 0.002 17.5 0.0 1.7 1 1 1 2 2 2 1 pfkB family carbohydrate kinase Lipase_3 PF01764.25 CAR21303.1 - 4.1e-09 36.4 0.0 8.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CAR21303.1 - 0.00098 18.4 0.0 0.0024 17.2 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR21303.1 - 0.0063 17.1 0.1 0.017 15.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 CAR21303.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 CAR21303.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CAR21303.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.18 CAR21304.1 - 1e-05 25.5 4.8 2.7e-05 24.2 4.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1864 PF08933.11 CAR21304.1 - 0.021 13.6 0.0 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) RsbU_N PF08673.10 CAR21304.1 - 0.026 14.6 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Pro_isomerase PF00160.21 CAR21305.1 - 7.6e-36 123.8 4.8 1e-35 123.4 1.0 2.2 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD cobW PF02492.19 CAR21306.1 - 9.3e-44 149.1 0.2 1.3e-43 148.7 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CAR21306.1 - 1.6e-07 31.1 0.1 3e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 CAR21306.1 - 2.2e-05 24.1 0.0 0.072 12.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CAR21306.1 - 0.0038 16.9 1.5 0.012 15.3 0.0 2.4 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CAR21306.1 - 0.0052 17.3 0.1 0.011 16.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CAR21306.1 - 0.0069 15.4 0.5 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CAR21306.1 - 0.0094 16.3 0.0 0.035 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 CAR21306.1 - 0.046 13.6 0.1 0.11 12.4 0.1 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CAR21306.1 - 0.057 14.0 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CAR21306.1 - 0.059 13.3 0.3 3.3 7.6 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 CAR21306.1 - 0.066 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CAR21306.1 - 0.078 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 CAR21306.1 - 0.095 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CAR21306.1 - 0.16 12.0 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 CAR21306.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 CAR21306.1 - 0.17 12.1 0.4 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_transf_22 PF03901.17 CAR21307.1 - 5.4e-30 104.9 13.0 7.6e-30 104.5 13.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CPP1-like PF11833.8 CAR21307.1 - 1 9.0 9.8 0.22 11.2 0.6 2.6 2 1 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Img2 PF05046.14 CAR21308.1 - 9.6e-22 77.1 0.1 1.4e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.22 CAR21308.1 - 0.14 12.7 0.4 0.39 11.3 0.4 1.7 1 1 0 1 1 1 0 Translation initiation factor SUI1 WD40 PF00400.32 CAR21309.1 - 3.4e-61 201.7 34.7 8.9e-12 45.3 0.0 9.2 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21309.1 - 8.1e-20 70.9 7.0 9.9e-06 25.8 0.2 5.4 3 2 2 6 6 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR21309.1 - 2.4e-09 37.4 0.3 0.00023 21.1 0.0 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 CAR21309.1 - 1.9e-08 34.7 0.0 3.7e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CAR21309.1 - 7.6e-07 28.4 1.3 0.21 10.5 0.0 5.0 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CAR21309.1 - 0.00022 20.0 3.4 2 6.9 0.6 4.9 3 2 2 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CAR21309.1 - 0.00047 19.0 0.8 0.0071 15.1 0.4 2.9 1 1 1 2 2 2 1 Nup133 N terminal like PD40 PF07676.12 CAR21309.1 - 0.0029 17.5 0.2 3 7.9 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CAR21309.1 - 0.003 17.0 0.7 0.68 9.2 0.1 3.1 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 CAR21309.1 - 0.0041 15.7 0.0 0.52 8.8 0.1 2.6 2 1 0 2 2 2 1 Cytochrome D1 heme domain Gmad1 PF10647.9 CAR21309.1 - 0.1 12.3 0.1 15 5.3 0.0 3.0 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Frtz PF11768.8 CAR21309.1 - 0.13 10.5 0.0 1.3 7.2 0.0 2.2 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 CAR21310.1 - 1e-68 231.6 0.0 3.3e-68 229.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21310.1 - 1.3e-38 132.7 0.0 3.1e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR21310.1 - 3e-05 23.5 0.6 0.0003 20.2 0.0 2.6 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 CAR21310.1 - 0.014 15.3 0.0 0.058 13.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAR21310.1 - 0.015 14.4 0.0 0.042 12.9 0.0 1.7 1 0 0 1 1 1 0 Seadornavirus VP7 Metallophos PF00149.28 CAR21311.1 - 1.9e-32 113.5 0.4 3.2e-32 112.7 0.1 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ubiquitin PF00240.23 CAR21312.1 - 1.2e-07 31.3 0.2 1.3e-07 31.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAR21312.1 - 0.00015 21.6 0.2 0.00016 21.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RAWUL PF16207.5 CAR21312.1 - 0.035 14.8 0.0 0.061 14.0 0.0 1.4 1 1 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Ubiquitin_2 PF14560.6 CAR21312.1 - 0.1 13.1 0.3 0.58 10.6 0.3 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Chorismate_bind PF00425.18 CAR21313.1 - 6.9e-67 225.7 0.0 1e-66 225.2 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CAR21313.1 - 4.3e-32 111.4 0.0 8.5e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CAR21313.1 - 2.2e-13 50.6 0.1 1.4e-12 48.1 0.0 2.3 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CAR21313.1 - 1e-06 28.6 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CP2 PF04516.15 CAR21313.1 - 0.17 11.1 0.0 0.51 9.6 0.0 1.7 2 0 0 2 2 2 0 CP2 transcription factor Blt1_C PF17183.4 CAR21313.1 - 0.19 11.3 0.2 6.6 6.4 0.1 2.4 2 0 0 2 2 2 0 Get5 carboxyl domain Glucosamine_iso PF01182.20 CAR21314.1 - 4.8e-53 180.3 0.0 2.1e-52 178.3 0.0 1.7 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PQ-loop PF04193.14 CAR21315.1 - 3.5e-21 74.7 10.7 2.1e-12 46.6 0.0 2.7 3 0 0 3 3 3 2 PQ loop repeat Phage_holin_3_3 PF16083.5 CAR21315.1 - 0.052 13.7 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III DUF588 PF04535.12 CAR21315.1 - 0.17 11.6 2.7 4.8 7.0 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF588) LMBR1 PF04791.16 CAR21316.1 - 3.7e-28 98.7 17.6 1.5e-27 96.7 17.6 1.8 1 1 0 1 1 1 1 LMBR1-like membrane protein Pox_A14 PF05767.12 CAR21316.1 - 0.00026 21.1 2.9 0.0058 16.8 2.0 2.9 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 TRIQK PF15168.6 CAR21316.1 - 2.1 8.3 4.4 0.61 10.0 0.2 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family SHR3_chaperone PF08229.11 CAR21316.1 - 2.2 7.2 6.0 0.22 10.5 1.4 1.6 2 0 0 2 2 2 0 ER membrane protein SH3 DUF3215 PF11503.8 CAR21317.1 - 1.2e-30 105.2 0.1 1.3e-30 105.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PI31_Prot_C PF08577.11 CAR21318.1 - 1.6e-08 35.6 15.7 1.6e-08 35.6 15.7 1.9 2 0 0 2 2 2 1 PI31 proteasome regulator PAT1 PF09770.9 CAR21319.1 - 8.2e-87 292.4 28.3 1.4e-84 285.0 28.3 3.2 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 P34-Arc PF04045.14 CAR21320.1 - 1.3e-96 323.0 1.8 1.5e-96 322.7 1.8 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Ribosom_S12_S23 PF00164.25 CAR21321.1 - 1.2e-31 108.7 1.2 1.6e-31 108.3 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 CAR21321.1 - 0.11 13.2 0.6 1.7 9.4 0.0 2.5 2 1 0 2 2 2 0 Ribosomal protein S12 PP2C PF00481.21 CAR21322.1 - 3.2e-35 122.0 0.0 1.2e-30 107.0 0.0 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CAR21322.1 - 0.0032 17.1 0.0 0.0072 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Thiol_cytolys_C PF17440.2 CAR21322.1 - 0.0082 16.3 0.2 0.76 10.0 0.1 2.3 2 0 0 2 2 2 1 Thiol-activated cytolysin beta sandwich domain Ribosomal_S19 PF00203.21 CAR21323.1 - 1.4e-25 89.0 0.0 1.8e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.29 CAR21324.1 - 1.3e-42 145.6 0.4 2.5e-42 144.6 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR21324.1 - 7.3e-23 81.0 0.6 2.6e-21 76.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR21324.1 - 4.1e-10 39.9 0.1 4.1e-10 39.9 0.1 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CAR21324.1 - 0.013 15.5 0.5 0.081 12.9 0.1 2.5 1 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 CAR21324.1 - 0.12 12.6 0.4 0.49 10.7 0.4 2.0 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CAR21324.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain BUD22 PF09073.10 CAR21324.1 - 1.5 8.1 14.3 2.4 7.4 14.3 1.3 1 0 0 1 1 1 0 BUD22 Med12 PF09497.10 CAR21325.1 - 4.1e-23 81.4 0.5 2.2e-22 79.1 0.3 2.3 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Cation_efflux PF01545.21 CAR21326.1 - 0.18 11.5 13.4 1 9.1 13.4 2.0 1 1 0 1 1 1 0 Cation efflux family UbiA PF01040.18 CAR21327.1 - 8.2e-47 159.6 12.0 1.1e-46 159.2 12.0 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Thioredoxin PF00085.20 CAR21329.1 - 1.6e-25 89.1 0.0 2e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 CAR21329.1 - 6.1e-05 22.9 0.0 7.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR21329.1 - 7.8e-05 22.4 0.0 9.2e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 CAR21329.1 - 0.00072 19.8 0.0 0.0014 18.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 CAR21329.1 - 0.0034 17.3 0.0 0.004 17.0 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 CAR21329.1 - 0.0056 16.1 0.0 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 CAR21329.1 - 0.0067 16.2 0.0 0.0084 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAR21329.1 - 0.009 16.5 0.1 0.029 14.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAR21329.1 - 0.039 14.1 0.1 0.059 13.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like MDD_C PF18376.1 CAR21331.1 - 1.7e-70 236.6 0.1 2.5e-70 236.0 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CAR21331.1 - 2.6e-09 37.2 2.0 7.6e-09 35.7 1.2 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain DUF1819 PF08849.11 CAR21331.1 - 0.081 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Zn_clus PF00172.18 CAR21332.1 - 1.2e-07 31.7 8.2 2e-07 31.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 CAR21333.1 - 8.6e-50 165.7 15.9 7.6e-09 36.1 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CAR21333.1 - 1.2e-29 102.4 11.2 1.2e-29 102.4 11.2 2.4 2 0 0 2 2 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CAR21333.1 - 1.7e-15 57.1 0.0 6.5e-05 23.2 0.0 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR21333.1 - 0.0017 17.8 0.0 2.2 7.5 0.0 3.8 3 1 2 5 5 5 2 WD40-like domain SRP-alpha_N PF04086.13 CAR21333.1 - 0.012 15.5 19.4 0.024 14.5 19.4 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CobT PF06213.12 CAR21333.1 - 0.038 13.4 29.2 0.072 12.5 29.2 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4746 PF15928.5 CAR21333.1 - 0.072 12.5 16.4 0.16 11.4 16.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Velvet PF11754.8 CAR21333.1 - 0.092 12.7 21.2 0.22 11.4 21.2 1.6 1 0 0 1 1 1 0 Velvet factor CPSF100_C PF13299.6 CAR21333.1 - 0.11 12.7 20.2 0.28 11.3 20.2 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 CAR21333.1 - 0.24 10.1 29.2 0.36 9.5 29.2 1.2 1 0 0 1 1 1 0 Presenilin SpoVR PF04293.13 CAR21333.1 - 0.29 9.8 20.3 0.43 9.2 20.3 1.1 1 0 0 1 1 1 0 SpoVR like protein Neur_chan_memb PF02932.16 CAR21333.1 - 0.3 11.1 16.4 0.51 10.4 16.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.8 CAR21333.1 - 0.3 9.8 17.9 0.49 9.1 17.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CCSAP PF15748.5 CAR21333.1 - 0.33 11.1 25.9 0.54 10.4 25.9 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 CAR21333.1 - 0.54 10.0 25.3 0.9 9.3 25.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ABC2_membrane_2 PF12679.7 CAR21333.1 - 0.55 9.5 2.9 0.9 8.8 2.9 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SAPS PF04499.15 CAR21333.1 - 0.7 8.6 21.0 0.98 8.1 21.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4050 PF13259.6 CAR21333.1 - 0.78 10.0 19.4 1.8 8.9 19.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) BAF1_ABF1 PF04684.13 CAR21333.1 - 0.86 8.6 26.7 1.2 8.1 26.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Endostatin PF06482.11 CAR21333.1 - 0.93 8.9 21.8 1.5 8.2 21.8 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 CAR21333.1 - 0.94 8.4 32.1 1.5 7.7 32.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Otopetrin PF03189.13 CAR21333.1 - 1.1 8.0 10.8 1.5 7.5 10.8 1.1 1 0 0 1 1 1 0 Otopetrin Baculo_PP31 PF05311.11 CAR21333.1 - 1.4 8.4 20.8 1.2 8.6 19.2 1.7 2 0 0 2 2 1 0 Baculovirus 33KDa late protein (PP31) Zip PF02535.22 CAR21333.1 - 1.5 7.9 10.6 2.2 7.4 10.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 CAR21333.1 - 1.8 7.2 21.2 2.8 6.6 21.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CAR21333.1 - 2 7.3 16.2 3.1 6.7 16.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4228 PF14009.6 CAR21333.1 - 2.6 8.4 12.7 7.8 6.8 12.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) TCP PF03634.13 CAR21333.1 - 2.7 8.5 25.2 5.7 7.5 25.2 1.6 1 0 0 1 1 1 0 TCP family transcription factor DUF4045 PF13254.6 CAR21333.1 - 2.7 7.5 26.6 4.7 6.7 26.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Rtf2 PF04641.12 CAR21333.1 - 2.8 7.2 22.0 4.7 6.5 22.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger AUX_IAA PF02309.16 CAR21333.1 - 2.9 7.7 15.0 4.8 7.0 15.0 1.4 1 0 0 1 1 1 0 AUX/IAA family GREB1 PF15782.5 CAR21333.1 - 2.9 4.9 29.4 3.8 4.5 29.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PIP5K PF01504.18 CAR21333.1 - 3 7.0 17.5 5.4 6.2 17.5 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Paf1 PF03985.13 CAR21333.1 - 3.3 6.6 34.5 5.3 5.9 34.5 1.2 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 CAR21333.1 - 3.3 5.5 29.5 4.9 4.9 29.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 CAR21333.1 - 3.8 7.5 19.6 6.5 6.7 19.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Rrn6 PF10214.9 CAR21333.1 - 3.9 5.8 36.0 5.8 5.3 36.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_S64 PF08192.11 CAR21333.1 - 5.1 5.5 19.5 8.2 4.8 19.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 CAR21333.1 - 5.2 5.2 52.5 8.4 4.5 52.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2828 PF11443.8 CAR21333.1 - 5.9 4.9 23.2 8.3 4.4 23.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2126 PF09899.9 CAR21333.1 - 6.8 4.6 16.1 10 4.0 16.1 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SLC12 PF03522.15 CAR21333.1 - 8.8 5.2 28.4 14 4.6 28.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Csm1_N PF18504.1 CAR21334.1 - 1.5e-29 102.1 4.7 1.5e-29 102.1 4.7 2.0 2 0 0 2 2 2 1 Csm1 N-terminal domain Csm1 PF12539.8 CAR21334.1 - 1e-23 83.7 0.0 1.7e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 DUF641 PF04859.12 CAR21334.1 - 0.0017 18.7 1.5 0.0039 17.5 1.5 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Spc24 PF08286.11 CAR21334.1 - 0.0064 16.7 0.6 0.014 15.6 0.1 1.7 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 TMCO5 PF14992.6 CAR21334.1 - 0.012 15.2 0.4 0.013 15.1 0.4 1.2 1 0 0 1 1 1 0 TMCO5 family BBP1_C PF15272.6 CAR21334.1 - 0.031 14.1 0.3 0.045 13.6 0.3 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal bZIP_1 PF00170.21 CAR21334.1 - 0.051 13.7 2.5 0.2 11.8 0.5 2.3 2 0 0 2 2 2 0 bZIP transcription factor DUF3450 PF11932.8 CAR21334.1 - 0.18 11.1 3.6 0.24 10.6 2.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PKcGMP_CC PF16808.5 CAR21334.1 - 0.19 11.6 4.0 0.19 11.6 0.7 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1043 PF06295.12 CAR21334.1 - 0.23 11.5 2.4 1.2 9.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) GAS PF13851.6 CAR21334.1 - 0.26 10.6 6.0 0.15 11.4 2.8 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 CAR21334.1 - 0.78 10.4 6.7 0.27 11.9 2.7 2.1 2 0 0 2 2 2 0 SlyX PspA_IM30 PF04012.12 CAR21334.1 - 0.89 9.1 9.4 0.047 13.3 4.4 1.4 2 0 0 2 2 2 0 PspA/IM30 family End3 PF12761.7 CAR21334.1 - 1.6 8.8 6.1 0.088 13.0 1.1 1.4 2 0 0 2 2 1 0 Actin cytoskeleton-regulatory complex protein END3 zf-LYAR PF08790.11 CAR21335.1 - 7.5e-14 51.3 6.0 1.6e-13 50.2 6.0 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 CAR21335.1 - 0.22 12.4 4.0 4.5 8.4 0.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 CAR21335.1 - 0.25 11.8 3.2 5.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Peptidase_C58 PF03543.14 CAR21335.1 - 0.38 10.4 9.2 0.48 10.1 9.2 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen CDC45 PF02724.14 CAR21335.1 - 1.1 7.4 11.5 1.3 7.2 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein C1_2 PF03107.16 CAR21335.1 - 7.7 6.9 11.5 2.1e+02 2.3 11.5 2.5 1 1 0 1 1 1 0 C1 domain Neur_chan_memb PF02932.16 CAR21335.1 - 7.9 6.5 7.8 8.5 6.4 7.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cofilin_ADF PF00241.20 CAR21336.1 - 1.4e-18 66.9 0.0 2.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 CAR21336.1 - 3.2e-14 52.3 0.6 8.3e-14 50.9 0.6 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR21336.1 - 3.8e-13 49.1 0.1 1e-12 47.7 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR21336.1 - 4.7e-07 29.4 0.0 9.5e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.6 CAR21337.1 - 1.7e-17 63.6 77.0 1.9e-06 28.3 10.8 16.0 13 5 3 16 16 16 6 Flocculin type 3 repeat Rsm1 PF08600.10 CAR21337.1 - 0.014 15.6 2.0 7.8 6.7 0.1 4.8 4 0 0 4 4 4 0 Rsm1-like DUF866 PF05907.13 CAR21338.1 - 3.7e-43 147.1 4.6 6.2e-43 146.4 4.6 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) GSH-S_N PF02951.14 CAR21338.1 - 0.2 11.8 0.0 0.73 10.0 0.0 1.8 1 1 1 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain DUF3795 PF12675.7 CAR21338.1 - 0.94 9.9 6.7 56 4.3 6.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Elf1 PF05129.13 CAR21338.1 - 2.8 8.0 7.5 3.1 7.9 4.2 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Trm112p PF03966.16 CAR21340.1 - 5.4e-20 71.8 0.1 6.5e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Pkinase PF00069.25 CAR21341.1 - 5.7e-79 265.2 0.2 7.6e-79 264.8 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21341.1 - 2.7e-32 112.1 0.2 1.3e-30 106.6 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR21341.1 - 6.9e-11 42.0 0.1 2.6e-06 27.0 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CAR21341.1 - 0.00083 18.2 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR21341.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR21341.1 - 0.24 11.3 0.0 16 5.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MutS_V PF00488.21 CAR21342.1 - 1.5e-64 217.5 0.0 3.1e-64 216.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR21342.1 - 9e-34 117.4 3.1 9e-34 117.4 3.1 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CAR21342.1 - 2.3e-29 101.9 0.1 4.2e-29 101.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CAR21342.1 - 7.9e-06 26.1 2.0 2.9e-05 24.3 0.5 2.5 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 CAR21342.1 - 0.00072 19.8 1.0 0.016 15.5 0.0 3.4 3 1 1 4 4 4 1 MutS domain II Not1 PF04054.15 CAR21343.1 - 9.9e-132 439.3 4.2 9.9e-132 439.3 4.2 3.5 2 1 1 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_HEAT_N PF16419.5 CAR21343.1 - 3.6e-87 291.8 4.4 3.6e-87 291.8 4.4 3.6 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_CAF1_bind PF16415.5 CAR21343.1 - 9.1e-85 283.6 7.6 9.1e-85 283.6 7.6 3.2 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CAR21343.1 - 7.9e-43 145.8 0.2 7.9e-43 145.8 0.2 4.2 4 1 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CAR21343.1 - 2.7e-42 144.1 7.0 2.7e-42 144.1 7.0 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CAR21343.1 - 1.5e-12 47.9 1.8 1.5e-12 47.9 1.8 6.1 6 1 0 6 6 6 1 CCR4-NOT transcription complex subunit 1 HEAT repeat TFIIA PF03153.13 CAR21343.1 - 5.4e-06 26.7 48.4 5.4e-06 26.7 48.4 2.7 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit FAM222A PF15258.6 CAR21343.1 - 0.0015 17.7 28.6 0.0015 17.7 28.6 2.6 2 0 0 2 2 2 1 Protein family of FAM222A DUF572 PF04502.13 CAR21343.1 - 7.1 6.1 22.8 1.7 8.2 15.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF4045 PF13254.6 CAR21343.1 - 8.9 5.8 25.0 2.5 7.6 17.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CDC50 PF03381.15 CAR21344.1 - 6.6e-94 314.5 0.3 7.9e-94 314.3 0.3 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family UQ_con PF00179.26 CAR21345.1 - 1.4e-43 147.9 0.0 1.8e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CAR21345.1 - 5.6e-27 93.3 0.3 1.2e-26 92.3 0.3 1.6 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_6 PF18039.1 CAR21345.1 - 0.00025 20.9 0.1 0.00049 20.0 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain GGA_N-GAT PF18308.1 CAR21345.1 - 0.0022 17.6 3.0 0.41 10.3 0.2 2.4 2 0 0 2 2 2 2 GGA N-GAT domain Calsarcin PF05556.11 CAR21345.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Mso1_Sec1_bdg PF14475.6 CAR21346.1 - 8.1e-19 66.9 0.1 1.4e-18 66.1 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sacchrp_dh_C PF16653.5 CAR21347.1 - 8.4e-93 311.3 0.0 1.2e-92 310.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CAR21347.1 - 1.5e-24 86.7 0.6 2.3e-24 86.1 0.6 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CAR21347.1 - 3.5e-07 30.3 0.4 5.8e-07 29.6 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 CAR21347.1 - 3.6e-07 30.3 0.2 7.7e-07 29.3 0.1 1.7 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 CAR21347.1 - 0.02 15.6 0.5 0.037 14.7 0.5 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CAR21347.1 - 0.03 13.3 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 CAR21347.1 - 0.088 12.3 0.3 0.14 11.7 0.3 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Y_phosphatase2 PF03162.13 CAR21348.1 - 1.3e-32 112.6 1.5 6.5e-31 107.1 1.5 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family NTF2 PF02136.20 CAR21349.1 - 5.1e-19 69.0 0.3 1e-18 68.1 0.3 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain CAF1 PF04857.20 CAR21350.1 - 1.1e-15 57.6 2.5 1.1e-10 41.2 0.2 2.3 1 1 1 2 2 2 2 CAF1 family ribonuclease NGP1NT PF08153.12 CAR21351.1 - 2.7e-50 169.8 0.2 5.4e-50 168.9 0.2 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CAR21351.1 - 1.2e-17 64.0 0.0 1.5e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR21351.1 - 1e-05 25.1 0.0 5.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CAR21351.1 - 9.8e-05 22.5 0.1 0.84 9.7 0.0 3.6 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 CAR21351.1 - 0.0011 18.5 0.1 0.29 10.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CAR21351.1 - 0.0018 18.2 0.0 0.0053 16.7 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CAR21351.1 - 0.0022 17.6 0.5 0.28 10.7 0.1 3.4 2 2 0 3 3 3 1 Elongation factor Tu GTP binding domain SusD-like_3 PF14322.6 CAR21351.1 - 0.03 14.7 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 Starch-binding associating with outer membrane RRM_1 PF00076.22 CAR21352.1 - 0.00016 21.5 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) B3 PF02362.21 CAR21352.1 - 0.079 12.8 0.9 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 B3 DNA binding domain Zip PF02535.22 CAR21353.1 - 1.5e-54 185.5 11.0 6.2e-54 183.5 11.0 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DLH PF01738.18 CAR21354.1 - 5.3e-31 107.9 0.1 6.2e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family PTCB-BRCT PF12738.7 CAR21354.1 - 0.082 12.9 0.0 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 twin BRCT domain Fungal_trans_2 PF11951.8 CAR21355.1 - 1.1e-49 169.3 3.6 1.4e-49 169.0 3.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21355.1 - 1.8e-09 37.5 11.0 4.1e-09 36.4 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_1 PF01979.20 CAR21356.1 - 3.7e-40 138.3 0.0 4.3e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR21356.1 - 5.1e-17 62.5 0.0 6.7e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 CAR21357.1 - 1.9e-37 129.0 27.1 1.9e-37 129.0 27.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Holin_BhlA PF10960.8 CAR21357.1 - 0.038 14.0 2.9 0.04 13.9 0.4 2.2 2 0 0 2 2 2 0 BhlA holin family MFS_1 PF07690.16 CAR21358.1 - 3e-12 46.2 43.0 9.5e-12 44.5 39.4 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR21358.1 - 1.2e-06 27.7 12.0 1.2e-06 27.7 12.0 3.5 3 1 1 4 4 4 1 Sugar (and other) transporter Herpes_U47 PF05467.11 CAR21358.1 - 0.15 10.2 0.0 0.22 9.6 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Spore_YhaL PF14147.6 CAR21358.1 - 7.5 6.3 5.9 8 6.2 0.8 3.3 4 0 0 4 4 4 0 Sporulation protein YhaL D-ser_dehydrat PF14031.6 CAR21359.1 - 5.9e-23 81.4 0.0 1.8e-22 79.8 0.0 1.9 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CAR21359.1 - 4.6e-13 49.3 0.0 6.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain adh_short_C2 PF13561.6 CAR21361.1 - 3.5e-40 138.0 0.0 4.2e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR21361.1 - 1.2e-31 109.7 0.2 1.4e-31 109.5 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR21361.1 - 7.9e-11 42.2 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.21 CAR21362.1 - 6.9e-61 206.0 0.0 8.7e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.12 CAR21362.1 - 0.036 13.6 0.0 0.074 12.6 0.0 1.5 2 0 0 2 2 2 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) MFS_1 PF07690.16 CAR21365.1 - 1.3e-12 47.3 39.5 9e-12 44.6 38.1 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR21365.1 - 6.8e-05 21.9 6.6 6.8e-05 21.9 6.6 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter MASE2 PF05230.11 CAR21365.1 - 1 9.5 4.6 1.2 9.2 1.6 2.7 2 0 0 2 2 2 0 MASE2 domain DUF21 PF01595.20 CAR21365.1 - 2.3 7.9 7.3 0.3 10.8 1.2 2.5 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain MFS_1 PF07690.16 CAR21366.1 - 6.5e-37 127.3 52.9 1.4e-34 119.6 49.3 3.0 2 1 1 3 3 3 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR21366.1 - 1.3e-14 53.5 16.3 1.5e-14 53.3 15.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3325 PF11804.8 CAR21366.1 - 1.8 8.8 6.3 0.21 11.8 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) AA_permease PF00324.21 CAR21367.1 - 1.2e-107 360.5 45.2 1.4e-107 360.3 45.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR21367.1 - 4.1e-21 75.3 48.9 5.2e-21 75.0 48.9 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.21 CAR21368.1 - 1.1e-15 57.7 0.0 1.5e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CAR21368.1 - 4.3e-05 22.5 0.0 0.00011 21.2 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_3 PF00202.21 CAR21369.1 - 3e-118 395.0 0.0 3.6e-118 394.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR21369.1 - 0.0027 17.0 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CAR21369.1 - 0.013 14.6 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Amidohydro_1 PF01979.20 CAR21370.1 - 9e-41 140.3 0.0 1.1e-40 140.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR21370.1 - 1.2e-15 58.0 0.0 3e-07 30.3 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family GATase PF00117.28 CAR21371.1 - 2.3e-12 47.1 0.0 3.3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CAR21371.1 - 0.0093 15.6 0.0 0.21 11.2 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 CAR21371.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase C26 Alpha-amylase PF00128.24 CAR21372.1 - 2.9e-125 418.3 0.1 4.4e-125 417.7 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CAR21372.1 - 0.00015 21.8 0.0 0.00034 20.7 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 CAR21372.1 - 0.0046 16.1 0.1 0.0087 15.2 0.1 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Sugar_tr PF00083.24 CAR21373.1 - 1e-168 561.9 33.5 1.2e-168 561.7 33.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR21373.1 - 3.4e-24 85.4 38.0 4.3e-23 81.8 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 CAR21374.1 - 7.1e-11 42.1 10.2 1.7e-10 40.8 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CheZ PF04344.13 CAR21375.1 - 0.099 12.5 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ ABC_tran PF00005.27 CAR21376.1 - 1.1e-54 184.6 0.1 4.3e-32 111.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CAR21376.1 - 1.1e-37 130.2 36.2 6.1e-23 81.8 12.7 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CAR21376.1 - 2.8e-10 40.0 4.2 0.013 14.9 0.1 4.0 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAR21376.1 - 1.3e-08 35.1 0.6 0.0038 17.1 0.0 3.9 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAR21376.1 - 2.3e-08 34.8 0.3 0.00019 22.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CAR21376.1 - 1.6e-07 31.0 0.7 0.014 15.1 0.0 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR21376.1 - 9.2e-06 25.7 0.1 0.0068 16.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CAR21376.1 - 3.8e-05 24.0 0.3 0.6 10.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 CAR21376.1 - 8.2e-05 22.1 0.1 0.041 13.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 CAR21376.1 - 0.00012 22.5 0.1 0.61 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CAR21376.1 - 0.00039 20.2 3.5 0.019 14.7 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 CAR21376.1 - 0.0004 20.4 0.3 0.24 11.5 0.2 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 CAR21376.1 - 0.0012 18.6 0.4 0.94 9.2 0.1 3.1 2 2 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAR21376.1 - 0.0014 18.8 1.3 0.011 15.9 0.2 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 CAR21376.1 - 0.0019 18.0 0.0 0.46 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 CAR21376.1 - 0.004 16.6 1.1 0.52 9.7 0.1 2.6 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.6 CAR21376.1 - 0.0063 16.7 0.0 4.4 7.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 CAR21376.1 - 0.0084 16.2 1.1 1.4 8.9 0.1 2.7 2 0 0 2 2 2 1 Dynamin family ATPase_2 PF01637.18 CAR21376.1 - 0.0097 15.8 0.0 16 5.4 0.0 3.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CAR21376.1 - 0.012 14.8 0.1 1.6 7.9 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain CbiA PF01656.23 CAR21376.1 - 0.018 15.1 0.2 9.2 6.3 0.0 3.5 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 CAR21376.1 - 0.019 14.5 0.1 8.2 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CAR21376.1 - 0.02 14.0 0.1 4 6.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 CAR21376.1 - 0.029 13.9 1.8 1.8 8.1 0.1 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF1430 PF07242.11 CAR21376.1 - 0.038 14.2 0.1 0.038 14.2 0.1 5.5 5 0 0 5 5 4 0 Protein of unknown function (DUF1430) AAA PF00004.29 CAR21376.1 - 0.072 13.5 0.0 15 6.0 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CAR21376.1 - 0.073 12.8 1.5 0.58 9.9 0.7 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 CAR21376.1 - 0.079 13.3 0.0 6.6 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 CAR21376.1 - 0.081 12.7 0.3 46 3.7 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 CAR21376.1 - 0.096 12.7 0.8 7.5 6.6 0.1 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CAR21376.1 - 0.1 12.5 0.1 5.8 6.8 0.1 2.8 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 CAR21376.1 - 0.16 11.7 0.4 3.8 7.2 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CAR21376.1 - 0.17 12.4 0.2 36 4.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CAR21376.1 - 0.2 10.9 0.1 19 4.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dak1 PF02733.17 CAR21377.1 - 4.2e-109 364.2 0.6 5.3e-109 363.9 0.6 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CAR21377.1 - 2e-45 154.8 2.0 4.3e-45 153.7 2.0 1.6 1 0 0 1 1 1 1 DAK2 domain MIP PF00230.20 CAR21378.1 - 5.4e-50 170.2 9.3 8.9e-50 169.5 9.3 1.3 1 0 0 1 1 1 1 Major intrinsic protein DUF4395 PF14340.6 CAR21378.1 - 1.6 9.0 11.5 0.21 11.9 2.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4395) FMO-like PF00743.19 CAR21379.1 - 2.3e-30 105.5 0.2 6.2e-16 57.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CAR21379.1 - 2.6e-09 36.8 0.0 2e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CAR21379.1 - 1.1e-08 34.7 0.0 1.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CAR21379.1 - 0.00024 20.4 0.0 0.032 13.4 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CAR21379.1 - 0.018 14.6 0.1 0.76 9.3 0.0 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase Proton_antipo_C PF01010.19 CAR21379.1 - 0.044 13.4 0.2 0.087 12.4 0.2 1.4 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus Mqo PF06039.15 CAR21379.1 - 0.053 12.1 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.6 CAR21379.1 - 0.083 12.9 0.1 1.6 8.7 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 CAR21380.1 - 4.2e-77 259.9 25.1 6.1e-77 259.4 25.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR21380.1 - 2.4e-25 89.2 28.8 2.4e-25 89.2 28.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 CAR21381.1 - 1.8e-12 47.4 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR21381.1 - 1.2e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Bac_luciferase PF00296.20 CAR21382.1 - 6.7e-47 160.4 0.0 1.1e-46 159.8 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 CAR21383.1 - 2e-14 53.3 25.3 2e-14 53.3 25.3 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family MFS_1 PF07690.16 CAR21385.1 - 1.1e-17 64.0 24.3 1.1e-17 64.0 24.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 CAR21386.1 - 1.2e-38 133.0 56.4 4.3e-32 111.4 35.0 2.9 2 1 2 4 4 4 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR21386.1 - 6.5e-09 35.1 20.6 6.5e-09 35.1 20.6 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CAR21386.1 - 4.7e-08 31.9 28.0 3e-07 29.2 28.0 2.0 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pam17 PF08566.10 CAR21386.1 - 0.085 12.7 0.2 0.33 10.8 0.2 2.0 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF3742 PF12553.8 CAR21386.1 - 0.14 12.3 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Pox_A14 PF05767.12 CAR21386.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.1 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 KSHV_K1 PF11049.8 CAR21388.1 - 0.048 13.6 2.2 5.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus Aa_trans PF01490.18 CAR21390.1 - 5.5e-26 91.2 37.9 6.9e-26 90.9 37.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mito_carr PF00153.27 CAR21391.1 - 1.8e-46 156.0 7.5 4.8e-19 68.1 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FoP_duplication PF13865.6 CAR21392.1 - 2.3e-09 37.6 1.6 3e-09 37.3 1.6 1.2 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Limkain-b1 PF11608.8 CAR21392.1 - 0.07 13.2 0.2 0.11 12.6 0.2 1.3 1 0 0 1 1 1 0 Limkain b1 CRCB PF02537.15 CAR21393.1 - 6.6e-32 109.7 19.2 2.3e-20 72.7 5.8 2.9 2 1 1 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) PUL PF08324.11 CAR21394.1 - 1.7e-40 139.0 0.0 2.4e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CAR21394.1 - 3.9e-36 123.8 0.1 7.7e-36 122.8 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CAR21394.1 - 8.6e-34 115.0 14.3 1.6e-07 31.9 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21394.1 - 0.0001 22.5 0.0 0.1 12.9 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Syja_N PF02383.18 CAR21395.1 - 2.9e-82 276.5 0.1 3.9e-82 276.1 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain IGPS PF00218.21 CAR21396.1 - 1.4e-87 293.1 0.1 2.1e-87 292.5 0.1 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 CAR21396.1 - 1.1e-47 162.2 0.0 1.9e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CAR21396.1 - 9.4e-09 35.3 0.1 2.2e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 CAR21396.1 - 0.00063 19.6 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peripla_BP_2 PF01497.18 CAR21396.1 - 0.0024 17.5 0.0 0.0067 16.0 0.0 1.7 1 0 0 1 1 1 1 Periplasmic binding protein VTC PF09359.10 CAR21396.1 - 0.076 12.4 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 VTC domain Glyco_tran_WecB PF03808.13 CAR21396.1 - 0.14 12.1 0.0 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Septin PF00735.18 CAR21397.1 - 1.9e-106 355.5 0.0 3.4e-106 354.6 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAR21397.1 - 6.5e-07 29.4 0.0 1.5e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CAR21397.1 - 3.2e-06 27.3 7.4 0.0017 18.4 0.4 3.1 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 CAR21397.1 - 8.9e-05 21.9 0.1 8.9e-05 21.9 0.1 1.9 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 CAR21397.1 - 0.003 18.1 0.6 0.0098 16.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CAR21397.1 - 0.0037 17.2 1.0 0.0037 17.2 1.0 3.1 3 1 0 3 3 3 1 RsgA GTPase IIGP PF05049.13 CAR21397.1 - 0.0088 15.1 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) G-alpha PF00503.20 CAR21397.1 - 0.02 14.0 1.8 0.3 10.2 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit Roc PF08477.13 CAR21397.1 - 0.032 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FAM199X PF15814.5 CAR21397.1 - 0.041 13.0 1.6 0.069 12.2 1.6 1.3 1 0 0 1 1 1 0 Protein family FAM199X GTP_EFTU PF00009.27 CAR21397.1 - 0.092 12.3 0.0 2.4 7.7 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CAR21397.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CAR21397.1 - 0.13 11.8 0.4 2.5 7.6 0.4 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CAR21397.1 - 0.14 11.9 0.2 16 5.3 0.0 2.5 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Gly_transf_sug PF04488.15 CAR21398.1 - 3.5e-12 46.8 0.0 9.7e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3987 PF13148.6 CAR21398.1 - 0.016 14.3 0.3 0.025 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Mog1 PF04603.12 CAR21399.1 - 1.8e-39 135.2 0.0 2.3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein ThiF PF00899.21 CAR21400.1 - 1.1e-110 368.8 0.0 9.5e-76 254.4 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CAR21400.1 - 3.2e-87 292.6 0.0 5.1e-87 292.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CAR21400.1 - 4e-35 120.4 0.2 1.1e-34 119.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 CAR21400.1 - 1.4e-27 95.6 0.2 2.8e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CAR21400.1 - 2.8e-23 81.9 1.0 6.5e-23 80.7 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle ABC_membrane PF00664.23 CAR21401.1 - 2.7e-97 325.7 22.7 5.3e-49 167.3 8.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAR21401.1 - 3.5e-61 205.7 0.1 2.5e-31 109.0 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR21401.1 - 2.3e-14 53.4 7.2 1.2e-06 28.2 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR21401.1 - 1.5e-07 31.1 2.1 0.0064 16.2 0.6 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR21401.1 - 5.5e-05 23.1 1.5 0.19 11.6 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 CAR21401.1 - 0.0001 22.8 0.1 1.3 9.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CAR21401.1 - 0.00033 20.7 0.8 1.8 8.6 0.1 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CAR21401.1 - 0.0015 18.6 0.3 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CAR21401.1 - 0.0022 18.1 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CAR21401.1 - 0.0049 16.7 7.3 2.6 7.8 0.7 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CAR21401.1 - 0.0096 16.3 8.4 1.2 9.4 1.1 3.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 CAR21401.1 - 0.0099 16.4 1.0 1 9.8 0.6 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR21401.1 - 0.011 16.1 4.1 2.7 8.2 0.5 3.8 2 2 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAR21401.1 - 0.011 15.3 1.3 4.4 6.8 0.6 3.0 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CAR21401.1 - 0.017 14.9 0.0 0.42 10.3 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.9 CAR21401.1 - 0.02 13.7 0.1 4.7 5.9 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class APS_kinase PF01583.20 CAR21401.1 - 0.028 14.3 0.7 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase HSP33 PF01430.19 CAR21401.1 - 0.09 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Hsp33 protein NACHT PF05729.12 CAR21401.1 - 0.21 11.5 3.0 11 5.9 0.0 3.4 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 CAR21401.1 - 0.35 10.6 1.5 9 6.0 0.0 2.9 2 2 0 2 2 2 0 AAA domain PEMT PF04191.13 CAR21402.1 - 8.9e-34 116.1 2.3 8.9e-34 116.1 2.3 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase MMR_HSR1_C PF08438.10 CAR21403.1 - 7.1e-35 120.0 0.0 1.1e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CAR21403.1 - 4.7e-20 71.8 0.0 9.3e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR21403.1 - 4.8e-07 29.4 0.1 4.8e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CAR21403.1 - 0.0027 17.3 0.1 1.3 8.5 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CAR21403.1 - 0.0055 16.1 0.2 0.8 9.0 0.1 2.2 2 0 0 2 2 2 2 FtsK/SpoIIIE family Dynamin_N PF00350.23 CAR21403.1 - 0.0085 16.2 0.3 0.025 14.7 0.2 1.8 2 0 0 2 2 2 1 Dynamin family KTI12 PF08433.10 CAR21403.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MeaB PF03308.16 CAR21403.1 - 0.14 11.1 0.7 1.1 8.2 0.0 2.6 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 CAR21403.1 - 0.17 11.7 0.3 10 5.8 0.1 2.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CAR21403.1 - 0.19 11.6 0.4 7.9 6.3 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CAR21403.1 - 0.2 12.2 0.0 0.63 10.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AA_permease PF00324.21 CAR21404.1 - 1.6e-124 416.1 42.1 2e-124 415.8 42.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR21404.1 - 9.4e-34 116.9 41.6 9.4e-34 116.9 41.6 1.5 1 1 1 2 2 2 1 Amino acid permease TPP_enzyme_N PF02776.18 CAR21405.1 - 8.2e-32 110.2 0.0 1.4e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR21405.1 - 1.4e-28 99.3 0.0 3.5e-27 94.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR21405.1 - 7e-13 48.6 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CAR21405.1 - 0.014 15.1 0.0 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF3234 PF11572.8 CAR21405.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) OCC1 PF15506.6 CAR21405.1 - 0.087 13.0 0.1 3.4 7.9 0.0 2.5 2 0 0 2 2 2 0 OCC1 family CLASP_N PF12348.8 CAR21407.1 - 2.5e-10 40.3 6.3 1.6e-09 37.7 0.3 2.7 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 CAR21407.1 - 0.00017 21.5 8.1 0.17 12.3 0.0 7.1 8 0 0 8 8 7 1 HEAT repeat Tropomyosin_1 PF12718.7 CAR21407.1 - 0.0028 17.8 4.0 0.014 15.6 4.0 2.2 1 0 0 1 1 1 1 Tropomyosin like TPR_MLP1_2 PF07926.12 CAR21407.1 - 0.0046 17.0 2.1 0.0046 17.0 2.1 2.9 3 0 0 3 3 2 1 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.12 CAR21407.1 - 0.0048 16.7 0.8 0.024 14.5 0.8 2.3 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat KASH_CCD PF14662.6 CAR21407.1 - 0.0057 16.5 5.4 0.019 14.8 5.4 1.9 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 CAR21407.1 - 0.0066 16.1 5.1 0.019 14.6 5.1 1.7 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 SPATA24 PF15175.6 CAR21407.1 - 0.023 14.6 5.7 0.067 13.1 5.7 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 DUF3450 PF11932.8 CAR21407.1 - 0.044 13.1 7.2 0.12 11.6 7.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3385 PF11865.8 CAR21407.1 - 0.051 13.5 0.3 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) TMPIT PF07851.13 CAR21407.1 - 0.056 12.7 3.5 0.13 11.5 3.5 1.5 1 0 0 1 1 1 0 TMPIT-like protein CCDC144C PF14915.6 CAR21407.1 - 0.057 12.5 9.6 0.02 14.0 5.0 2.2 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 CAR21407.1 - 0.072 13.1 10.3 49 3.9 10.4 3.5 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_BLRF2 PF05812.12 CAR21407.1 - 0.075 13.2 1.8 0.27 11.4 1.8 2.0 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein UME PF08064.13 CAR21407.1 - 0.075 13.0 0.3 4.5 7.2 0.0 3.1 3 0 0 3 3 3 0 UME (NUC010) domain DUF1981 PF09324.10 CAR21407.1 - 0.12 12.3 0.1 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) TSC22 PF01166.18 CAR21407.1 - 0.16 12.3 2.5 1.7 9.0 0.2 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family HemX PF04375.14 CAR21407.1 - 0.2 10.9 6.3 0.49 9.6 6.3 1.6 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase UPF0242 PF06785.11 CAR21407.1 - 0.2 11.8 6.6 0.43 10.7 6.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4763 PF15960.5 CAR21407.1 - 0.23 10.7 12.3 0.23 10.7 7.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF3552 PF12072.8 CAR21407.1 - 0.24 10.8 4.6 0.51 9.7 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) JIP_LZII PF16471.5 CAR21407.1 - 0.25 11.6 6.2 3.5 7.9 0.9 2.9 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 CAR21407.1 - 0.28 11.7 9.6 0.37 11.3 6.5 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Rootletin PF15035.6 CAR21407.1 - 0.28 11.2 15.5 0.052 13.6 8.1 2.7 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 CAR21407.1 - 0.35 11.0 8.0 1.4 9.0 8.0 2.0 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4094 PF13334.6 CAR21407.1 - 0.36 11.3 3.9 0.67 10.4 3.1 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4094) Med9 PF07544.13 CAR21407.1 - 0.54 10.4 8.5 11 6.2 6.3 3.7 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_23 PF13476.6 CAR21407.1 - 0.57 10.6 4.4 1.5 9.2 4.4 1.7 1 0 0 1 1 1 0 AAA domain Sec2p PF06428.11 CAR21407.1 - 0.62 10.1 6.2 1.9 8.5 6.2 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF641 PF04859.12 CAR21407.1 - 0.82 10.0 7.9 0.45 10.9 4.4 2.3 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) ZapB PF06005.12 CAR21407.1 - 0.94 10.0 11.4 4.3 7.8 7.3 4.0 3 1 0 3 3 2 0 Cell division protein ZapB DUF4201 PF13870.6 CAR21407.1 - 1.6 8.4 10.4 1.2 8.9 8.4 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4201) Spc24 PF08286.11 CAR21407.1 - 1.9 8.8 9.8 1.3e+02 2.9 7.5 3.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Golgin_A5 PF09787.9 CAR21407.1 - 2.4 7.5 11.5 0.15 11.5 6.0 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 bZIP_1 PF00170.21 CAR21407.1 - 2.9 8.1 6.3 3.9 7.7 0.1 3.2 2 1 1 3 3 2 0 bZIP transcription factor Spc7 PF08317.11 CAR21407.1 - 4.1 6.2 11.3 0.79 8.5 7.1 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Csm1_N PF18504.1 CAR21407.1 - 4.4 7.7 7.7 66 3.9 3.7 3.9 3 1 0 3 3 2 0 Csm1 N-terminal domain ATG16 PF08614.11 CAR21407.1 - 5 7.3 16.7 0.33 11.1 10.4 2.3 3 0 0 3 3 1 0 Autophagy protein 16 (ATG16) bZIP_2 PF07716.15 CAR21407.1 - 5.6 7.1 7.9 3.3 7.9 0.1 3.2 3 0 0 3 3 2 0 Basic region leucine zipper ERM PF00769.19 CAR21407.1 - 6.9 6.4 11.9 24 4.6 12.0 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family OmpH PF03938.14 CAR21407.1 - 6.9 7.0 10.7 25 5.2 0.1 3.0 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Thioredoxin PF00085.20 CAR21408.1 - 1.4e-31 108.5 0.5 1.6e-31 108.3 0.5 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAR21408.1 - 5.8e-06 26.7 0.4 2.2e-05 24.9 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CAR21408.1 - 8.1e-06 25.6 0.1 8.7e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAR21408.1 - 1.2e-05 25.6 0.1 0.00011 22.5 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CAR21408.1 - 0.00015 21.5 0.2 0.0022 17.7 0.0 1.9 1 1 1 2 2 2 1 Redoxin DIM1 PF02966.16 CAR21408.1 - 0.0002 21.2 0.0 0.00021 21.1 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.21 CAR21408.1 - 0.00032 20.6 0.1 0.00035 20.5 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CAR21408.1 - 0.002 17.5 0.1 0.0023 17.3 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CAR21408.1 - 0.025 14.4 0.2 0.03 14.1 0.2 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CAR21408.1 - 0.026 14.7 0.2 0.054 13.7 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 CAR21408.1 - 0.052 12.5 0.0 0.053 12.5 0.0 1.0 1 0 0 1 1 1 0 Phosducin Hydrolase PF00702.26 CAR21409.1 - 4.4e-16 59.8 0.9 7e-16 59.1 0.9 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR21409.1 - 2.3e-14 54.2 0.0 3.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAR21409.1 - 4e-07 30.0 0.0 6.5e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR21409.1 - 2.8e-05 24.3 0.6 0.0066 16.6 0.1 2.7 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CAR21409.1 - 3.3e-05 23.4 0.0 5.9e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.12 CAR21409.1 - 0.053 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Acid_PPase PF12689.7 CAR21409.1 - 0.15 11.9 0.0 0.61 9.9 0.0 1.9 1 1 0 1 1 1 0 Acid Phosphatase ETF PF01012.21 CAR21410.1 - 6.2e-43 146.8 0.7 7.5e-43 146.5 0.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Mvb12 PF09452.10 CAR21411.1 - 1.1e-31 109.1 0.1 1.2e-31 108.9 0.1 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 3-HAO PF06052.12 CAR21412.1 - 1.1e-64 216.6 0.2 1.3e-64 216.4 0.2 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CAR21412.1 - 3e-05 23.6 0.1 5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain zf_C2H2_13 PF18508.1 CAR21412.1 - 0.0058 16.2 0.5 0.014 14.9 0.2 1.8 2 0 0 2 2 2 1 Zinc finger domain zf-B_box PF00643.24 CAR21412.1 - 0.01 15.9 3.0 0.065 13.4 0.4 2.3 2 0 0 2 2 2 0 B-box zinc finger Cupin_1 PF00190.22 CAR21412.1 - 0.019 14.6 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 Cupin FYVE PF01363.21 CAR21412.1 - 0.02 15.0 1.1 0.034 14.3 1.1 1.3 1 0 0 1 1 1 0 FYVE zinc finger AraC_binding PF02311.19 CAR21412.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain ribosomal_L24 PF17136.4 CAR21412.1 - 0.15 12.5 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 zinc_ribbon_2 PF13240.6 CAR21412.1 - 0.22 11.3 4.9 4 7.3 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-RanBP PF00641.18 CAR21412.1 - 0.81 9.1 4.2 0.8 9.1 0.2 2.2 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others A2L_zn_ribbon PF08792.10 CAR21412.1 - 7.9 6.3 7.6 0.68 9.7 0.3 2.4 2 1 0 2 2 2 0 A2L zinc ribbon domain Aldolase_II PF00596.21 CAR21413.1 - 5e-46 157.0 0.0 6.2e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2202 PF09968.9 CAR21413.1 - 0.06 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) LSM PF01423.22 CAR21414.1 - 6.4e-12 45.0 0.2 1.2e-11 44.1 0.1 1.5 2 0 0 2 2 2 1 LSM domain Zeta_toxin PF06414.12 CAR21415.1 - 0.00014 21.2 0.0 0.00048 19.5 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin PRK PF00485.18 CAR21415.1 - 0.001 18.9 0.0 0.003 17.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 CAR21415.1 - 0.0017 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 CAR21415.1 - 0.002 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 CAR21415.1 - 0.0088 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CAR21415.1 - 0.0098 16.4 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAR21415.1 - 0.016 15.7 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CAR21415.1 - 0.018 15.3 0.0 0.047 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CAR21415.1 - 0.025 14.7 0.1 0.063 13.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 CAR21415.1 - 0.03 13.8 0.0 0.082 12.4 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.29 CAR21415.1 - 0.032 14.6 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 CAR21415.1 - 0.041 13.8 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase cobW PF02492.19 CAR21415.1 - 0.045 13.3 0.0 0.075 12.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CAR21415.1 - 0.049 13.4 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAR21415.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR21415.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 CAR21415.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase Bac_DnaA PF00308.18 CAR21415.1 - 0.089 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_14 PF13173.6 CAR21415.1 - 0.089 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAR21415.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_Helicase PF02689.14 CAR21415.1 - 0.19 9.6 0.0 0.27 9.1 0.0 1.1 1 0 0 1 1 1 0 Helicase 4HBT_3 PF13622.6 CAR21416.1 - 4.1e-38 132.1 0.1 5.6e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CAR21416.1 - 8.6e-31 106.5 0.4 3.6e-25 88.3 0.1 3.1 2 1 1 3 3 3 2 Acyl-CoA thioesterase p12I PF12233.8 CAR21416.1 - 0.098 13.2 0.7 0.098 13.2 0.7 1.6 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein FTHFS PF01268.19 CAR21417.1 - 9.3e-254 842.8 0.2 1.2e-253 842.4 0.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CAR21417.1 - 9e-60 200.6 0.9 1.6e-59 199.8 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CAR21417.1 - 1.7e-40 137.9 0.1 3.6e-40 136.8 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 CAR21417.1 - 0.021 14.9 0.0 0.14 12.2 0.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rotamase PF00639.21 CAR21419.1 - 5.9e-24 84.9 0.0 8.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CAR21419.1 - 8.9e-18 64.9 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CAR21419.1 - 8.1e-09 35.4 1.7 1.2e-08 34.8 1.7 1.3 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CAR21419.1 - 2.2e-06 28.5 0.0 3.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rhodanese PF00581.20 CAR21420.1 - 1.8e-08 34.8 0.0 2.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_like PF01467.26 CAR21421.1 - 3.2e-31 108.5 0.0 6.7e-31 107.4 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like SDA1 PF05285.12 CAR21421.1 - 4.3 6.7 25.7 0.3 10.4 12.4 2.2 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 CAR21421.1 - 9.7 4.3 29.5 2.2 6.5 2.2 2.1 2 0 0 2 2 2 0 CDC45-like protein ILVD_EDD PF00920.21 CAR21422.1 - 2.9e-208 692.7 0.1 3.3e-208 692.5 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.32 CAR21423.1 - 6.3e-37 124.9 9.7 6.2e-05 23.7 0.0 10.7 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21423.1 - 1.2e-13 51.2 3.4 0.0018 18.5 0.0 8.1 4 2 5 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain PMT PF02366.18 CAR21424.1 - 9.2e-84 280.8 15.1 9.2e-84 280.8 15.1 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR21424.1 - 1.9e-54 184.3 16.3 1.9e-54 184.3 16.3 2.3 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR21424.1 - 4.1e-23 82.2 0.4 7.5e-23 81.3 0.4 1.3 1 0 0 1 1 1 1 MIR domain TPR_17 PF13431.6 CAR21425.1 - 7.3e-05 22.9 3.1 0.57 10.7 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR21425.1 - 0.00011 22.7 5.8 0.12 12.9 0.2 5.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR21425.1 - 0.015 16.1 0.2 30 5.8 0.0 4.8 3 1 1 4 4 4 0 Tetratricopeptide repeat SUI1 PF01253.22 CAR21426.1 - 2.6e-21 75.9 1.7 7.3e-21 74.5 1.7 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 NKWYS PF10364.9 CAR21426.1 - 3.7 7.7 6.0 2.4 8.3 0.8 2.1 1 1 1 2 2 2 0 Putative capsular polysaccharide synthesis protein RNase_PH PF01138.21 CAR21428.1 - 1.3e-28 100.2 0.2 1.8e-28 99.7 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAR21428.1 - 8.3e-06 25.7 0.1 2.1e-05 24.4 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.13 CAR21429.1 - 1.3e-79 267.7 22.6 1.3e-79 267.7 22.6 2.2 3 0 0 3 3 3 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 CAR21429.1 - 4.4e-07 29.9 13.3 4.4e-07 29.9 13.3 2.0 1 1 1 2 2 2 1 Glycosyltransferase family 87 PIG-U PF06728.13 CAR21429.1 - 3.5e-05 23.0 30.9 7e-05 22.1 30.9 1.6 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF5572 PF17733.1 CAR21430.1 - 1.4e-11 44.0 0.6 2.3e-11 43.4 0.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Mito_carr PF00153.27 CAR21431.1 - 1.5e-49 165.9 3.5 4.8e-18 64.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SPC12 PF06645.13 CAR21433.1 - 5.4e-21 74.5 0.1 6.2e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.16 CAR21433.1 - 0.012 14.6 0.7 0.013 14.4 0.7 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily PRA1 PF03208.19 CAR21433.1 - 0.057 13.0 0.7 0.067 12.8 0.7 1.1 1 0 0 1 1 1 0 PRA1 family protein SpecificRecomb PF10136.9 CAR21433.1 - 0.29 9.4 3.1 0.36 9.1 3.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase FGGY_N PF00370.21 CAR21434.1 - 7.6e-24 84.6 0.0 6.4e-15 55.4 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CAR21434.1 - 1.4e-15 57.5 0.0 1.4e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Biotin_lipoyl PF00364.22 CAR21435.1 - 1.2e-21 76.3 0.9 2.8e-21 75.1 0.9 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CAR21435.1 - 7.8e-08 32.5 0.0 2.5e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CAR21435.1 - 0.011 15.6 2.1 0.38 10.6 0.0 2.7 2 1 1 3 3 3 0 Biotin-lipoyl like AstE_AspA PF04952.14 CAR21435.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family ATP-sulfurylase PF01747.17 CAR21436.1 - 1.1e-86 289.7 0.0 1.6e-86 289.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CAR21436.1 - 8.3e-51 171.8 0.0 1.3e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Methyltransf_11 PF08241.12 CAR21437.1 - 1.2e-16 61.1 0.0 3.7e-16 59.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR21437.1 - 4.1e-16 59.4 0.0 1.8e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR21437.1 - 1.6e-12 48.0 0.0 2.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR21437.1 - 1.8e-07 31.1 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR21437.1 - 4.5e-07 29.8 0.0 6.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAR21437.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CAR21437.1 - 0.084 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SelB-wing_3 PF09107.11 CAR21437.1 - 0.16 11.6 1.0 26 4.6 0.0 2.8 3 0 0 3 3 3 0 Elongation factor SelB, winged helix Gp_dh_C PF02800.20 CAR21438.1 - 2.2e-71 238.6 0.0 3.3e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CAR21438.1 - 2e-39 134.0 0.0 5.2e-39 132.7 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CAR21438.1 - 0.04 14.0 0.7 0.13 12.4 0.1 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 CAR21438.1 - 0.044 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Memo PF01875.17 CAR21439.1 - 1.6e-84 283.3 0.1 1.9e-84 283.1 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein EIF_2_alpha PF07541.12 CAR21440.1 - 2.9e-38 130.5 0.2 6.7e-38 129.3 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CAR21440.1 - 2.1e-15 56.8 1.7 3.8e-15 56.0 1.7 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SLIDE PF09111.10 CAR21440.1 - 0.056 13.5 1.3 0.16 12.0 0.0 2.4 3 1 0 3 3 3 0 SLIDE Amidohydro_1 PF01979.20 CAR21440.1 - 0.13 11.5 0.3 0.21 10.9 0.3 1.2 1 0 0 1 1 1 0 Amidohydrolase family Rap_GAP PF02145.15 CAR21441.1 - 1e-44 152.3 0.5 2.1e-44 151.3 0.5 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 CAR21441.1 - 6.3e-22 78.2 1.0 3.1e-18 66.0 0.1 2.6 2 0 0 2 2 2 2 Tuberin DUF3384 PF11864.8 CAR21441.1 - 3.8e-15 55.7 3.0 1.4e-13 50.6 0.0 2.8 3 1 0 3 3 3 2 Domain of unknown function (DUF3384) Cnd1 PF12717.7 CAR21441.1 - 0.1 12.6 0.6 11 6.1 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 AA_permease PF00324.21 CAR21442.1 - 8.7e-138 459.9 31.5 1e-137 459.6 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR21442.1 - 1.1e-39 136.5 35.0 1.4e-39 136.2 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4231 PF14015.6 CAR21442.1 - 0.096 13.2 3.7 15 6.1 0.3 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Glyco_hydro_16 PF00722.21 CAR21443.1 - 1.9e-46 157.7 2.8 1.9e-46 157.7 2.8 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 RNA_pol_Rpb4 PF03874.16 CAR21444.1 - 5.7e-34 117.1 0.3 6.5e-34 116.9 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 VTC PF09359.10 CAR21445.1 - 2.4e-101 338.8 0.2 2.4e-101 338.8 0.2 1.8 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CAR21445.1 - 1.7e-12 48.0 15.8 1.8e-05 24.8 2.0 4.4 4 1 1 5 5 5 3 SPX domain DUF202 PF02656.15 CAR21445.1 - 4.5e-10 39.8 2.6 8.9e-10 38.9 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Mad3_BUB1_I PF08311.12 CAR21446.1 - 2.6e-43 146.9 0.7 5.3e-43 145.9 0.7 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 CAR21446.1 - 7.9e-27 93.2 0.0 2.3e-26 91.7 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 CAR21446.1 - 1.5e-17 63.9 0.0 2.8e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21446.1 - 1e-06 28.2 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 CAR21446.1 - 1.4e-06 28.5 0.1 4e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Cpn60_TCP1 PF00118.24 CAR21447.1 - 3.7e-163 543.7 3.3 4.2e-163 543.5 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2433 PF10360.9 CAR21447.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2433) Sad1_UNC PF07738.13 CAR21449.1 - 3.7e-07 30.2 0.0 7.7e-06 25.9 0.0 2.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Zein-binding PF04576.15 CAR21449.1 - 0.026 14.8 0.3 0.083 13.2 0.3 1.9 1 0 0 1 1 1 0 Zein-binding Baculo_PEP_C PF04513.12 CAR21449.1 - 0.35 10.9 5.7 0.15 12.1 2.5 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 CAR21449.1 - 0.36 11.2 4.3 0.15 12.4 0.5 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 CAR21449.1 - 1 8.6 2.8 5.3 6.2 1.3 2.2 2 0 0 2 2 2 0 TMPIT-like protein UPF0242 PF06785.11 CAR21449.1 - 1.4 9.0 8.1 0.15 12.2 2.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 CAR21449.1 - 2.1 6.2 5.1 0.5 8.3 1.9 1.5 2 0 0 2 2 2 0 Prominin Bot1p PF12298.8 CAR21450.1 - 3.1e-60 203.2 0.6 4.1e-60 202.9 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein Trs65 PF12735.7 CAR21451.1 - 3.6e-24 85.7 2.3 2.1e-21 76.7 2.3 3.1 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Clathrin_lg_ch PF01086.17 CAR21452.1 - 4.7e-56 190.4 27.2 5.4e-56 190.2 27.2 1.0 1 0 0 1 1 1 1 Clathrin light chain PET PF06297.14 CAR21452.1 - 0.63 10.4 5.6 4.1 7.8 0.8 2.5 2 1 0 2 2 2 0 PET Domain SH3_1 PF00018.28 CAR21454.1 - 4.2e-09 35.9 0.2 4.2e-09 35.9 0.2 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CAR21454.1 - 1.6e-07 30.9 0.0 3.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CAR21454.1 - 1.2e-06 28.3 0.1 2.5e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PseudoU_synth_2 PF00849.22 CAR21455.1 - 3.8e-31 108.3 0.1 1e-30 107.0 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase zf-TFIIB PF13453.6 CAR21455.1 - 0.31 10.4 1.7 4.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger CCDC106 PF15794.5 CAR21457.1 - 0.73 9.5 10.9 0.83 9.3 10.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3602 PF12223.8 CAR21457.1 - 0.75 10.4 8.6 0.19 12.3 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) HPIP PF15226.6 CAR21457.1 - 1.1 9.7 3.3 1.3 9.4 3.3 1.1 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family MAJIN PF15077.6 CAR21457.1 - 1.2 8.9 9.8 1.3 8.8 9.8 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein PS_Dcarbxylase PF02666.15 CAR21458.1 - 4.7e-55 186.3 0.0 1.1e-54 185.1 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CAR21458.1 - 2.1e-22 79.4 0.2 6.4e-13 48.9 0.1 2.8 2 0 0 2 2 2 2 C2 domain DNA_pol_E_B PF04042.16 CAR21459.1 - 2e-38 131.9 0.4 4.8e-38 130.6 0.4 1.6 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CAR21459.1 - 1.6e-37 128.5 0.4 3.8e-37 127.3 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase delta subunit OB-fold domain Elong-fact-P_C PF09285.11 CAR21459.1 - 0.026 14.3 0.1 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 Elongation factor P, C-terminal tRNA-synt_1g PF09334.11 CAR21460.1 - 1.4e-89 300.6 0.0 3.8e-89 299.2 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CAR21460.1 - 1e-20 73.5 0.0 3.6e-10 38.8 0.0 3.1 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CAR21460.1 - 1.8e-10 40.6 0.0 0.00039 19.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CAR21460.1 - 0.00082 19.4 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Yip1 PF04893.17 CAR21461.1 - 2.2e-13 50.3 10.9 3e-13 49.9 10.9 1.2 1 0 0 1 1 1 1 Yip1 domain MMR_HSR1_Xtn PF16897.5 CAR21462.1 - 5.5e-35 119.6 1.3 9.4e-35 118.8 1.3 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CAR21462.1 - 7.5e-21 74.3 0.1 1.4e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CAR21462.1 - 5.4e-20 71.2 0.0 1.2e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CAR21462.1 - 1.3e-12 47.5 0.0 2.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CAR21462.1 - 0.00021 21.4 0.2 0.033 14.2 0.0 2.4 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 CAR21462.1 - 0.003 16.9 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 CAR21462.1 - 0.007 15.8 0.6 0.033 13.6 0.1 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MCM PF00493.23 CAR21462.1 - 0.01 14.9 0.1 0.08 12.0 0.0 2.1 2 0 0 2 2 2 0 MCM P-loop domain AAA_16 PF13191.6 CAR21462.1 - 0.07 13.5 0.2 0.15 12.5 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 CAR21462.1 - 0.074 13.3 0.5 0.17 12.1 0.1 2.0 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF1178 PF06676.11 CAR21462.1 - 0.076 13.4 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) GTP_EFTU PF00009.27 CAR21462.1 - 0.08 12.5 1.5 4.5 6.8 0.4 3.2 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain NMT1 PF09084.11 CAR21463.1 - 4e-77 259.0 0.0 4.9e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CAR21463.1 - 0.00034 20.4 0.0 0.067 12.9 0.0 2.6 3 0 0 3 3 3 2 NMT1-like family 2Fe-2S_thioredx PF01257.19 CAR21463.1 - 0.027 14.3 1.4 0.045 13.6 1.4 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Ribosomal_L24e PF01246.20 CAR21465.1 - 8.1e-32 109.3 4.8 1.7e-31 108.2 4.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Pam16 PF03656.13 CAR21466.1 - 2.8e-06 27.4 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CAR21466.1 - 0.0024 17.9 0.1 0.0047 17.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Yip1 PF04893.17 CAR21466.1 - 0.02 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain SMC_Nse1 PF07574.13 CAR21467.1 - 2.9e-41 141.5 0.0 3.7e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CAR21467.1 - 1.5e-08 34.8 11.6 2.7e-08 34.0 11.6 1.4 1 0 0 1 1 1 1 RING-like domain Response_reg PF00072.24 CAR21468.1 - 3.9e-20 72.1 0.2 3.4e-13 49.7 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Adaptin_N PF01602.20 CAR21469.1 - 3.7e-94 316.2 10.0 4.4e-94 315.9 10.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR21469.1 - 2.3e-15 57.0 1.4 2.1e-14 53.9 0.1 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vitellogenin_N PF01347.22 CAR21469.1 - 0.085 11.2 3.5 0.091 11.1 0.1 2.5 3 0 0 3 3 3 0 Lipoprotein amino terminal region UME PF08064.13 CAR21469.1 - 0.12 12.3 1.1 5.1 7.1 0.1 3.4 3 0 0 3 3 3 0 UME (NUC010) domain Exo84_C PF16528.5 CAR21469.1 - 0.73 9.6 3.5 11 5.8 1.2 3.0 2 1 0 2 2 2 0 Exocyst component 84 C-terminal CMS1 PF14617.6 CAR21470.1 - 7.7e-15 54.9 13.7 2.2e-12 46.9 13.7 2.9 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Dendrin PF15498.6 CAR21470.1 - 0.0098 14.7 3.1 0.015 14.1 3.1 1.2 1 0 0 1 1 1 1 Nephrin and CD2AP-binding protein, Dendrin PolyA_pol_RNAbd PF12627.7 CAR21470.1 - 0.036 13.8 0.9 0.17 11.6 0.4 2.1 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A AXIN1_TNKS_BD PF16646.5 CAR21470.1 - 0.048 14.6 2.2 0.11 13.4 2.2 1.7 1 0 0 1 1 1 0 Axin-1 tankyrase binding domain RR_TM4-6 PF06459.12 CAR21470.1 - 1.3 8.8 10.4 0.29 10.9 7.1 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.16 CAR21471.1 - 1.5e-35 122.8 19.6 7.2e-35 120.5 21.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 CAR21471.1 - 0.09 13.0 0.4 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_92 PF07971.12 CAR21472.1 - 6.9e-124 414.3 1.0 9e-124 413.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CAR21472.1 - 1.9e-48 165.4 4.7 2.7e-48 165.0 4.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Ssl1 PF04056.14 CAR21473.1 - 1.6e-88 295.6 0.1 2.2e-88 295.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 CAR21473.1 - 1.9e-26 92.1 11.7 1.9e-26 92.1 11.7 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CAR21473.1 - 5.9e-16 59.1 0.0 1.2e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CAR21473.1 - 4.9e-08 33.4 0.0 8e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain PBP1_TM PF14812.6 CAR21473.1 - 1.5 9.3 5.8 3.5 8.1 5.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Tfb4 PF03850.14 CAR21473.1 - 4.3 6.8 7.6 11 5.4 7.6 1.7 1 0 0 1 1 1 0 Transcription factor Tfb4 MFS_1 PF07690.16 CAR21474.1 - 1.2e-30 106.6 17.7 1.2e-30 106.6 17.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Candida_ALS_N PF11766.8 CAR21475.1 - 3.2e-66 223.1 4.5 3.2e-66 223.1 4.5 2.8 3 0 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding TPR_8 PF13181.6 CAR21476.1 - 0.056 13.7 0.1 28 5.3 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR21476.1 - 0.11 12.6 0.4 20 5.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NOC3p PF07540.11 CAR21478.1 - 4e-29 100.9 1.4 4e-29 100.9 1.4 2.9 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 CAR21478.1 - 1.3e-24 87.1 3.3 2.5e-24 86.2 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Herpes_UL36 PF03586.13 CAR21478.1 - 0.098 12.0 1.7 2.4 7.4 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus UL36 tegument protein DUF502 PF04367.13 CAR21478.1 - 0.15 12.0 0.0 19 5.2 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF502) T3SS_basalb_I PF17001.5 CAR21478.1 - 5.1 7.7 9.7 0.39 11.3 1.5 3.1 3 0 0 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI Mpp10 PF04006.12 CAR21479.1 - 2.9e-149 498.4 38.8 3.5e-149 498.1 38.8 1.0 1 0 0 1 1 1 1 Mpp10 protein PRESAN PF09687.10 CAR21479.1 - 0.064 13.8 0.5 0.36 11.4 0.0 2.4 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Aa_trans PF01490.18 CAR21480.1 - 2.6e-74 250.4 23.8 3.3e-74 250.1 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Prominin PF05478.11 CAR21480.1 - 1 7.2 3.0 1.4 6.8 3.0 1.2 1 0 0 1 1 1 0 Prominin RRM_1 PF00076.22 CAR21481.1 - 2.6e-15 56.0 0.1 3.8e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fasciclin PF02469.22 CAR21482.1 - 4e-22 78.8 5.0 1.2e-07 32.0 0.1 5.7 5 1 0 5 5 5 5 Fasciclin domain Dynamin_M PF01031.20 CAR21483.1 - 1.3e-107 359.3 0.0 2e-107 358.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CAR21483.1 - 2.4e-53 180.6 0.5 7.1e-53 179.1 0.0 2.1 2 1 0 2 2 2 1 Dynamin family GED PF02212.18 CAR21483.1 - 9.3e-30 102.6 3.7 1.3e-29 102.2 2.5 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CAR21483.1 - 3.9e-06 26.9 0.2 0.00022 21.2 0.2 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CAR21483.1 - 0.074 12.8 1.4 0.095 12.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 CAR21483.1 - 0.081 12.4 0.1 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B HAT_KAT11 PF08214.11 CAR21484.1 - 2.4e-97 326.4 0.0 2.8e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 Histone acetylation protein Proteasome PF00227.26 CAR21485.1 - 4.1e-47 160.1 1.4 4.7e-47 159.9 1.4 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1_C PF10638.9 CAR21486.1 - 1e-37 129.1 5.2 4.9e-37 126.9 5.2 2.3 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Sfi1 PF08457.10 CAR21486.1 - 2e-15 56.4 84.9 1.3e-12 47.1 73.0 3.3 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF1127 PF06568.11 CAR21486.1 - 0.98 9.2 7.3 24 4.8 1.3 5.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1127) Ribophorin_I PF04597.14 CAR21487.1 - 3.9e-122 408.6 0.5 4.5e-122 408.4 0.5 1.0 1 0 0 1 1 1 1 Ribophorin I ORC_WH_C PF18137.1 CAR21488.1 - 4.4e-24 85.1 0.0 7.8e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 CAR21488.1 - 1.6e-07 30.8 7.3 2.3e-07 30.3 2.5 2.4 3 0 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus COX16 PF14138.6 CAR21489.1 - 5.9e-31 106.8 0.9 6.5e-31 106.7 0.1 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 MFS_1 PF07690.16 CAR21489.1 - 0.11 11.4 0.1 0.14 11.0 0.1 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily RSN1_7TM PF02714.15 CAR21490.1 - 3.8e-71 239.6 22.5 1e-70 238.2 22.5 1.8 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR21490.1 - 8.8e-32 110.0 0.9 8.8e-32 110.0 0.9 3.5 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CAR21490.1 - 0.00011 22.5 7.8 0.00088 19.5 6.3 2.8 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CAR21490.1 - 0.0035 17.5 0.0 0.0089 16.2 0.0 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MMM1 PF10296.9 CAR21491.1 - 5.6e-144 479.2 0.1 7.2e-144 478.9 0.1 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 CRR7 PF12095.8 CAR21491.1 - 0.042 14.3 0.4 16 6.0 0.0 2.9 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Prominin PF05478.11 CAR21491.1 - 0.63 7.9 2.8 1.7 6.5 0.1 2.0 2 0 0 2 2 2 0 Prominin PH_12 PF16457.5 CAR21492.1 - 6.3e-07 30.0 2.8 1.6e-06 28.7 0.4 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain DEAD PF00270.29 CAR21493.1 - 7.2e-46 156.1 0.1 1.4e-45 155.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR21493.1 - 3.9e-29 101.2 2.0 9.5e-28 96.8 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CAR21493.1 - 0.053 13.8 0.3 0.22 11.8 0.3 2.0 1 1 0 1 1 1 0 AAA domain SYS1 PF09801.9 CAR21494.1 - 1.3e-47 161.6 13.1 1.5e-47 161.3 13.1 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PP2C PF00481.21 CAR21495.1 - 4.6e-47 160.8 0.6 8.4e-47 160.0 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_8 PF13855.6 CAR21495.1 - 2.8e-39 132.7 84.8 5.6e-09 35.6 4.7 10.2 6 3 3 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 CAR21495.1 - 1.4e-37 127.1 102.4 7.6e-07 29.4 6.7 12.3 10 2 2 12 12 12 9 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CAR21495.1 - 1.7e-26 93.0 0.0 4.1e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 CAR21495.1 - 0.0045 16.5 39.6 0.071 12.6 3.3 5.5 1 1 5 6 6 6 4 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 CAR21495.1 - 0.0071 16.0 0.1 0.016 14.9 0.1 1.6 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 CAR21495.1 - 0.042 14.5 0.0 0.094 13.4 0.0 1.6 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.6 CAR21495.1 - 1.1 9.2 12.7 2.1 8.3 1.9 3.8 2 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CAR21495.1 - 7.5 7.5 78.5 5.2 8.0 1.6 15.8 14 2 1 15 15 15 0 Leucine Rich Repeat PNP_UDP_1 PF01048.20 CAR21496.1 - 1.4e-35 122.6 0.0 1.7e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.11 CAR21497.1 - 2.6e-26 92.2 0.4 4e-26 91.6 0.4 1.2 1 0 0 1 1 1 1 Nuclear pore complex component NIF PF03031.18 CAR21498.1 - 2e-52 177.1 0.1 2.9e-52 176.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sof1 PF04158.14 CAR21499.1 - 2.1e-28 98.4 12.3 2.1e-28 98.4 12.3 2.0 2 0 0 2 2 2 1 Sof1-like domain WD40 PF00400.32 CAR21499.1 - 1e-25 89.5 6.8 9.9e-07 29.4 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21499.1 - 3.3e-07 30.5 0.4 0.13 12.5 0.0 4.8 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR21499.1 - 1.2e-05 24.4 1.2 0.0021 17.1 0.2 3.2 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CAR21499.1 - 0.0023 18.0 0.4 0.16 12.0 0.0 3.7 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CAR21499.1 - 0.0094 15.3 0.7 0.14 11.5 0.0 2.7 3 0 0 3 3 3 1 WD40-like domain Utp8 PF10395.9 CAR21499.1 - 0.067 11.7 2.8 0.18 10.3 0.6 2.0 1 1 1 2 2 2 0 Utp8 family Abhydro_lipase PF04083.16 CAR21500.1 - 8.4e-15 54.1 0.0 1.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CAR21500.1 - 3.8e-08 33.3 0.0 6.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR21500.1 - 0.0008 18.7 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 CAR21500.1 - 0.0055 16.2 0.0 0.0096 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.12 CAR21500.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) POC3_POC4 PF10448.9 CAR21501.1 - 5.7e-31 107.5 0.0 6.6e-31 107.3 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 SBDS_C PF09377.10 CAR21502.1 - 3.5e-31 107.6 0.5 3.5e-31 107.6 0.5 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 CAR21502.1 - 1.2e-30 105.4 5.1 1.9e-30 104.8 5.1 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HlyIII PF03006.20 CAR21503.1 - 5.9e-56 189.7 16.4 5.9e-56 189.7 16.4 1.5 2 0 0 2 2 2 1 Haemolysin-III related TssN PF17555.2 CAR21503.1 - 0.0039 16.6 3.6 0.0039 16.6 3.6 2.1 1 1 1 2 2 2 1 Type VI secretion system, TssN PAP1 PF08601.10 CAR21503.1 - 0.39 10.4 4.2 0.54 9.9 4.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 FAM199X PF15814.5 CAR21503.1 - 1.7 7.6 10.1 2.8 6.9 10.1 1.2 1 0 0 1 1 1 0 Protein family FAM199X PUF PF00806.19 CAR21504.1 - 1e-50 166.6 10.0 2.4e-07 30.1 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.12 CAR21505.1 - 2.6e-21 76.0 5.7 3e-21 75.8 5.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.14 CAR21506.1 - 1.4e-63 214.0 4.8 1.5e-63 214.0 0.6 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CAR21506.1 - 9.2e-22 76.7 0.5 2.9e-21 75.1 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) TFIIF_alpha PF05793.12 CAR21507.1 - 8.6e-10 37.8 0.2 8.6e-10 37.8 0.2 3.3 1 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1b PF00579.25 CAR21508.1 - 4.8e-75 252.6 0.0 6.2e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.20 CAR21509.1 - 5.2e-13 49.0 9.1 3.8e-12 46.2 9.1 2.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 CAR21509.1 - 0.24 11.6 10.1 0.023 14.8 4.4 2.4 2 0 0 2 2 2 0 B-box zinc finger ZZ PF00569.17 CAR21509.1 - 0.39 10.6 11.2 0.17 11.7 7.9 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-UBR PF02207.20 CAR21510.1 - 4.7e-17 61.9 14.5 4.7e-17 61.9 14.5 2.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CAR21510.1 - 1.4e-05 24.8 0.0 3.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 CAR21510.1 - 0.0018 18.5 0.9 0.0018 18.5 0.9 3.2 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 CAR21510.1 - 0.0046 16.9 1.0 0.0046 16.9 1.0 3.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CAR21510.1 - 0.0068 16.7 0.2 0.0068 16.7 0.2 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain GP38 PF05268.11 CAR21510.1 - 0.014 15.1 0.0 0.039 13.6 0.0 1.6 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 UCR_UQCRX_QCR9 PF05365.12 CAR21511.1 - 2.2e-26 91.6 3.4 2.4e-26 91.4 3.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-Tim10_DDP PF02953.15 CAR21512.1 - 9.9e-20 70.0 1.2 1.7e-19 69.2 1.2 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MIEAP PF16026.5 CAR21512.1 - 0.023 14.9 0.6 0.026 14.7 0.6 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein NES_C_h PF18208.1 CAR21512.1 - 0.054 13.8 0.1 0.073 13.3 0.1 1.3 1 0 0 1 1 1 0 Nicking enzyme C-terminal middle helical domain Clat_adaptor_s PF01217.20 CAR21513.1 - 5.4e-56 188.5 0.9 6.5e-56 188.2 0.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adaptin_N PF01602.20 CAR21513.1 - 0.096 11.2 0.4 0.2 10.1 0.1 1.5 1 1 0 1 1 1 0 Adaptin N terminal region CBP4 PF07960.11 CAR21514.1 - 4.1e-57 191.6 4.4 4.9e-57 191.4 4.4 1.1 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 CAR21514.1 - 0.00023 21.0 3.8 0.00074 19.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF4662 PF15578.6 CAR21514.1 - 0.014 15.2 1.1 0.015 15.1 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Ribosomal_L18_c PF14204.6 CAR21514.1 - 0.023 15.6 1.9 0.049 14.6 1.9 1.5 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region GPHR_N PF12537.8 CAR21514.1 - 0.047 13.8 0.2 0.24 11.5 0.2 1.9 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal IclR PF01614.18 CAR21514.1 - 0.28 11.0 2.4 1.4 8.8 0.7 2.1 2 0 0 2 2 2 0 Bacterial transcriptional regulator Pet100 PF09803.9 CAR21514.1 - 0.86 10.2 4.1 0.48 11.0 1.0 2.0 2 0 0 2 2 2 0 Pet100 LAMTOR PF15454.6 CAR21514.1 - 1.1 10.0 8.4 0.78 10.4 0.8 2.3 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SE PF08491.10 CAR21515.1 - 3e-124 413.5 0.0 3.9e-124 413.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CAR21515.1 - 1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CAR21515.1 - 4.9e-06 26.4 0.1 0.00091 18.9 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CAR21515.1 - 0.012 16.2 0.1 0.042 14.4 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR21515.1 - 0.032 14.4 0.1 0.079 13.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAR21515.1 - 0.033 13.4 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 CAR21515.1 - 0.065 12.3 1.1 0.1 11.6 0.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 CAR21515.1 - 0.13 11.5 0.6 0.22 10.9 0.1 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AATase PF07247.12 CAR21516.1 - 2.1e-135 452.1 0.0 2.4e-135 452.0 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase zf-RRN7 PF11781.8 CAR21517.1 - 6.4e-10 38.5 1.8 1.2e-09 37.6 1.8 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 LsmAD PF06741.13 CAR21518.1 - 2.1e-29 101.9 1.5 6.5e-29 100.3 0.2 2.5 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 CAR21518.1 - 1.2e-13 50.9 0.1 3.1e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain CENP-Q PF13094.6 CAR21519.1 - 8.8e-05 22.8 4.4 0.0002 21.6 4.4 1.7 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Speriolin_C PF15059.6 CAR21519.1 - 0.0068 16.5 1.2 0.017 15.2 0.7 1.9 1 1 1 2 2 2 1 Speriolin C-terminus His_leader PF08047.11 CAR21519.1 - 0.44 10.6 1.9 0.98 9.5 1.9 1.5 1 0 0 1 1 1 0 Histidine operon leader peptide MFS_1 PF07690.16 CAR21520.1 - 4.8e-36 124.4 28.8 4.8e-36 124.4 28.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR21520.1 - 2.8e-11 43.0 24.5 4.8e-11 42.2 24.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CAR21520.1 - 5.1e-10 38.4 1.3 7.7e-10 37.8 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CAR21520.1 - 0.0008 18.8 3.5 0.0008 18.8 3.5 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MgtE PF01769.16 CAR21520.1 - 1.2 9.5 17.6 5 7.5 0.1 4.1 4 1 0 5 5 5 0 Divalent cation transporter Thi4 PF01946.17 CAR21521.1 - 5.7e-107 356.3 0.1 6.8e-107 356.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CAR21521.1 - 5.2e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR21521.1 - 1.4e-05 25.2 0.1 6.2e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAR21521.1 - 7.3e-05 22.0 0.8 0.00028 20.1 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 CAR21521.1 - 0.00016 21.7 0.1 0.0012 18.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CAR21521.1 - 0.00029 20.0 0.4 0.00046 19.3 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CAR21521.1 - 0.00031 20.1 0.3 0.00059 19.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR21521.1 - 0.003 17.0 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CAR21521.1 - 0.0062 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR21521.1 - 0.017 13.9 0.4 0.031 13.0 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CAR21521.1 - 0.059 12.4 0.2 0.092 11.8 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CAR21521.1 - 0.078 11.8 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Ribonuc_red_sm PF00268.21 CAR21522.1 - 5e-119 396.9 2.8 6.3e-119 396.6 2.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 CAR21522.1 - 0.11 13.3 0.0 0.23 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) RE_XcyI PF09571.10 CAR21522.1 - 0.12 11.6 1.1 0.6 9.3 0.1 2.2 3 0 0 3 3 3 0 XcyI restriction endonuclease NDK PF00334.19 CAR21524.1 - 9.2e-55 184.4 0.0 1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SRF-TF PF00319.18 CAR21525.1 - 8.3e-21 73.2 0.1 1.2e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Sporozoite_P67 PF05642.11 CAR21525.1 - 0.00082 17.6 1.8 0.00085 17.5 1.8 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Spt5_N PF11942.8 CAR21525.1 - 0.0086 17.0 9.5 0.0086 17.0 9.5 1.9 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 CAR21525.1 - 0.032 12.5 6.5 0.049 11.9 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein CCDC53 PF10152.9 CAR21525.1 - 0.22 12.0 14.9 0.067 13.6 11.7 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Nop14 PF04147.12 CAR21525.1 - 0.22 9.7 8.9 0.29 9.3 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 CAR21525.1 - 0.23 10.6 3.2 0.3 10.3 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CAR21525.1 - 0.34 9.6 6.1 0.43 9.3 6.1 1.2 1 0 0 1 1 1 0 Presenilin FAM220 PF15487.6 CAR21525.1 - 0.37 10.4 2.5 0.58 9.7 2.5 1.3 1 0 0 1 1 1 0 FAM220 family eIF3_subunit PF08597.10 CAR21525.1 - 0.69 9.8 12.0 1.1 9.1 12.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SLAIN PF15301.6 CAR21525.1 - 0.79 8.9 8.1 1.1 8.5 8.1 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Hid1 PF12722.7 CAR21525.1 - 0.82 7.7 3.9 0.91 7.6 3.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sigma70_ner PF04546.13 CAR21525.1 - 6.7 6.5 10.6 0.97 9.3 6.4 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Lin-8 PF03353.15 CAR21525.1 - 6.8 6.2 13.6 10 5.6 13.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2052 PF09747.9 CAR21525.1 - 8.7 6.4 15.6 13 5.9 15.5 1.4 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PWWP PF00855.17 CAR21526.1 - 1.1e-20 73.8 1.1 1.5e-20 73.4 0.1 1.8 2 0 0 2 2 2 1 PWWP domain HEPN_Toprim_N PF18871.1 CAR21526.1 - 0.12 12.3 2.4 0.23 11.3 2.4 1.5 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Hid1 PF12722.7 CAR21526.1 - 4 5.5 7.9 5.4 5.0 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoporin_FG PF13634.6 CAR21527.1 - 1e-97 321.2 623.0 2.9e-16 60.1 38.5 12.9 3 2 14 17 17 17 15 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CAR21527.1 - 6e-41 140.0 0.0 9.6e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Swi3 PF07962.12 CAR21528.1 - 1.3e-27 95.6 0.2 1.8e-27 95.1 0.2 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Cwf_Cwc_15 PF04889.12 CAR21528.1 - 0.00013 21.8 1.1 0.00018 21.3 1.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SF1-HH PF16275.5 CAR21528.1 - 0.09 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain CENP-B_dimeris PF09026.10 CAR21528.1 - 0.53 10.7 7.3 1.2 9.5 7.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 CAR21528.1 - 2 7.7 4.8 2.5 7.3 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein CLPTM1 PF05602.12 CAR21529.1 - 5.7e-82 276.0 0.1 7.8e-82 275.6 0.1 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF2474 PF10617.9 CAR21529.1 - 5.7 6.9 5.5 1.2 9.1 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) BOP1NT PF08145.12 CAR21530.1 - 2.6e-104 348.8 8.1 5.2e-104 347.8 8.1 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CAR21530.1 - 1.1e-23 83.0 4.5 9.7e-10 38.9 0.2 6.5 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21530.1 - 6.8e-08 32.7 0.9 0.0056 17.0 0.0 5.3 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain GAF_2 PF13185.6 CAR21531.1 - 2.3e-10 40.9 0.0 3.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CAR21531.1 - 1.7e-06 28.7 0.0 2.2e-06 28.3 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CAR21531.1 - 0.0024 18.2 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 GAF domain DUF1413 PF07205.11 CAR21532.1 - 0.047 13.7 0.3 3.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) DUF4061 PF13270.6 CAR21532.1 - 0.55 10.6 4.3 4 7.8 1.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) bZIP_2 PF07716.15 CAR21532.1 - 7.9 6.7 11.9 3.8 7.7 1.6 3.6 3 1 1 4 4 4 0 Basic region leucine zipper CENP-F_leu_zip PF10473.9 CAR21533.1 - 0.0012 18.8 3.0 0.0023 18.0 3.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 CAR21533.1 - 0.017 14.9 0.0 0.041 13.7 0.0 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Lectin_N PF03954.14 CAR21533.1 - 0.18 11.6 4.0 0.11 12.3 0.9 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain V_ATPase_I PF01496.19 CAR21534.1 - 0 1013.3 3.7 0 1013.1 3.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.12 CAR21534.1 - 0.036 14.1 0.8 5 7.2 0.0 2.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PHM7_cyt PF14703.6 CAR21534.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter BLOC1_2 PF10046.9 CAR21534.1 - 0.22 11.8 0.6 2.7 8.4 0.1 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 CAR21534.1 - 0.45 11.2 2.1 7.3 7.3 0.1 3.0 3 0 0 3 3 3 0 SlyX CLZ PF16526.5 CAR21534.1 - 0.77 10.2 2.7 1.2 9.6 0.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSP70 PF00012.20 CAR21535.1 - 2.9e-51 174.4 5.3 2.6e-49 168.0 0.0 2.5 3 0 0 3 3 3 2 Hsp70 protein PilM_2 PF11104.8 CAR21535.1 - 0.02 14.0 0.1 0.055 12.5 0.0 1.7 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; RRM_1 PF00076.22 CAR21536.1 - 0.00093 19.0 0.1 0.0029 17.4 0.1 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.18 CAR21537.1 - 6.9e-34 117.4 0.0 9.2e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cu-oxidase_2 PF07731.14 CAR21538.1 - 5.4e-47 159.0 8.7 8.7e-40 135.6 0.7 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAR21538.1 - 5.2e-45 152.3 3.3 3.4e-41 140.0 0.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CAR21538.1 - 2.9e-31 108.8 10.2 3.6e-30 105.2 2.6 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CAR21538.1 - 0.037 14.2 0.0 5.2 7.2 0.0 3.3 3 0 0 3 3 3 0 Cupredoxin-like domain Self-incomp_S1 PF05938.11 CAR21538.1 - 0.037 14.6 0.2 1.3 9.7 0.0 2.8 3 0 0 3 3 3 0 Plant self-incompatibility protein S1 DUF4448 PF14610.6 CAR21540.1 - 7.2e-56 189.0 0.1 1.2e-55 188.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF5390 PF17365.2 CAR21540.1 - 0.0046 17.2 0.5 0.014 15.6 0.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF5390) RDD PF06271.12 CAR21540.1 - 0.14 12.3 0.1 0.28 11.4 0.1 1.4 1 0 0 1 1 1 0 RDD family Sen15 PF09631.10 CAR21541.1 - 3.3e-27 94.7 0.0 3.7e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein Tom37_C PF11801.8 CAR21542.1 - 8e-45 152.4 0.1 1.1e-44 151.9 0.1 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.9 CAR21542.1 - 7.8e-30 103.8 1.4 1.4e-29 102.9 1.4 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Suf PF05843.14 CAR21543.1 - 4e-62 210.9 12.1 4.1e-55 187.8 2.6 4.8 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) Latarcin PF10279.9 CAR21543.1 - 0.00021 21.6 0.2 0.38 11.2 0.1 3.5 3 0 0 3 3 3 2 Latarcin precursor TPR_14 PF13428.6 CAR21543.1 - 0.00091 19.9 0.0 0.27 12.2 0.1 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR21543.1 - 0.0079 16.8 0.0 0.31 11.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR21543.1 - 0.025 15.1 0.0 0.24 11.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR21543.1 - 0.039 14.3 0.8 2.7 8.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat P4Ha_N PF08336.11 CAR21543.1 - 0.098 12.7 1.2 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ArgJ PF01960.18 CAR21544.1 - 3.2e-145 483.6 5.3 3.6e-145 483.4 5.3 1.0 1 0 0 1 1 1 1 ArgJ family K-cyclin_vir_C PF09080.10 CAR21544.1 - 0.15 12.5 0.7 0.63 10.5 0.2 2.3 2 0 0 2 2 2 0 K cyclin, C terminal Sugar_tr PF00083.24 CAR21545.1 - 2e-116 389.6 17.4 2.3e-116 389.3 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR21545.1 - 1.6e-21 76.6 13.8 1.6e-21 76.6 13.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OppC_N PF12911.7 CAR21545.1 - 0.046 13.7 3.9 0.31 11.0 0.2 3.8 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ANTH PF07651.16 CAR21547.1 - 2.4e-66 223.6 1.0 4.8e-66 222.6 1.0 1.5 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CAR21547.1 - 2.8e-06 27.4 2.8 3e-06 27.3 0.0 2.5 3 1 0 3 3 3 1 ENTH domain PFK PF00365.20 CAR21548.1 - 1.1e-184 612.3 1.8 1.9e-104 349.0 0.2 2.2 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 CAR21548.1 - 1.2e-27 96.2 0.1 2.4e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 CAR21548.1 - 0.029 14.0 0.2 0.39 10.4 0.1 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 CAR21548.1 - 0.17 11.7 0.4 0.38 10.6 0.4 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Tht1 PF04163.12 CAR21549.1 - 6.5e-38 130.8 11.0 1.2e-37 129.9 11.0 1.4 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF2451 PF10474.9 CAR21549.1 - 0.037 13.8 2.1 0.049 13.4 0.2 2.2 2 2 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Apolipoprotein PF01442.18 CAR21549.1 - 0.046 13.6 0.3 3.7 7.4 0.1 2.5 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Bacillus_HBL PF05791.11 CAR21549.1 - 0.3 10.9 7.1 8 6.3 0.0 3.5 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 CAR21549.1 - 1.5 8.9 6.2 6.3 6.8 0.4 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus KapB PF08810.10 CAR21549.1 - 2.6 8.3 5.0 11 6.2 0.5 3.2 2 1 1 3 3 3 0 Kinase associated protein B AEP1 PF17049.5 CAR21550.1 - 1.2e-135 452.6 0.4 1.5e-135 452.3 0.4 1.1 1 0 0 1 1 1 1 ATPase expression protein 1 SUR7 PF06687.12 CAR21551.1 - 5.5e-26 91.5 12.6 7.5e-26 91.1 12.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family FA_desaturase PF00487.24 CAR21551.1 - 0.0077 16.1 4.6 0.011 15.6 4.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase CobD_Cbib PF03186.13 CAR21551.1 - 0.018 14.3 3.9 0.015 14.5 2.4 1.6 2 0 0 2 2 2 0 CobD/Cbib protein Orf78 PF06024.12 CAR21551.1 - 0.61 10.4 0.0 0.61 10.4 0.0 2.6 3 1 0 3 3 3 0 Orf78 (ac78) DUF4191 PF13829.6 CAR21551.1 - 1.7 7.9 3.2 3.4 7.0 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4231 PF14015.6 CAR21551.1 - 7 7.2 9.8 13 6.3 2.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) HA2 PF04408.23 CAR21552.1 - 7.2e-21 74.5 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR21552.1 - 1e-11 45.0 0.0 3.1e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR21552.1 - 5.8e-11 42.7 0.0 3.3e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR21552.1 - 2.3e-10 40.5 0.1 3.8e-10 39.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR21552.1 - 4.1e-07 30.3 0.1 8.5e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR21552.1 - 0.0017 18.7 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR21552.1 - 0.0025 17.6 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CAR21552.1 - 0.0046 17.0 0.1 0.014 15.4 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.6 CAR21552.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CAR21552.1 - 0.0074 16.8 0.0 0.02 15.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 CAR21552.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CAR21552.1 - 0.015 14.7 0.0 0.044 13.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MTCP1 PF08991.10 CAR21552.1 - 0.019 15.2 0.3 0.041 14.1 0.3 1.5 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type AAA_14 PF13173.6 CAR21552.1 - 0.022 14.8 0.3 0.32 11.0 0.3 2.4 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 CAR21552.1 - 0.027 14.7 0.0 0.081 13.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CAR21552.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 CAR21552.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CAR21552.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras family ATPase PF06745.13 CAR21552.1 - 0.12 11.7 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 CAR21552.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CAR21552.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 CAR21552.1 - 0.18 12.3 1.5 0.96 9.9 1.5 2.1 1 1 0 1 1 1 0 AAA domain GATase_2 PF00310.21 CAR21554.1 - 1.7e-168 560.7 0.0 2.7e-168 560.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CAR21554.1 - 1.3e-153 511.6 0.0 3.4e-153 510.1 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CAR21554.1 - 6e-114 380.2 0.0 5.1e-110 367.3 0.0 3.2 3 0 0 3 3 3 2 Glutamate synthase central domain GXGXG PF01493.19 CAR21554.1 - 1.7e-70 236.5 1.3 3.2e-70 235.6 1.3 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CAR21554.1 - 3.4e-22 79.0 0.9 2.9e-21 76.0 0.9 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CAR21554.1 - 3.6e-22 78.3 0.1 6.8e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CAR21554.1 - 4.8e-09 36.3 0.0 1.3e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CAR21554.1 - 8.3e-07 29.5 0.2 0.00013 22.4 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR21554.1 - 1.3e-06 27.9 0.4 0.013 14.7 0.0 3.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CAR21554.1 - 3e-06 26.8 0.1 8.9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CAR21554.1 - 6.5e-05 21.8 1.4 6.9e-05 21.7 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CAR21554.1 - 0.00012 21.6 0.1 0.00023 20.6 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 CAR21554.1 - 0.0002 21.1 0.6 0.00073 19.2 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CAR21554.1 - 0.00052 19.2 0.0 0.00099 18.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain AdoHcyase_NAD PF00670.21 CAR21554.1 - 0.0051 16.9 1.7 4.7 7.3 0.0 3.6 3 0 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.19 CAR21554.1 - 0.0054 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 CAR21554.1 - 0.008 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 CAR21554.1 - 0.019 14.2 0.6 0.059 12.6 0.1 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 CAR21554.1 - 0.028 14.8 0.8 5.9 7.4 0.0 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding GATase_6 PF13522.6 CAR21554.1 - 0.032 14.4 0.0 0.098 12.9 0.0 1.8 1 0 0 1 1 1 0 Glutamine amidotransferase domain FMN_dh PF01070.18 CAR21554.1 - 0.092 11.8 0.6 0.41 9.6 0.8 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase MADF_DNA_bdg PF10545.9 CAR21554.1 - 0.13 12.6 0.7 0.49 10.7 0.2 2.1 2 0 0 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like F420_oxidored PF03807.17 CAR21554.1 - 0.17 12.5 0.3 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 CAR21554.1 - 0.17 10.9 0.1 0.31 10.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein EcoR124_C PF12008.8 CAR21554.1 - 0.42 10.2 7.7 0.78 9.3 7.7 1.3 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal GIDA PF01134.22 CAR21554.1 - 2.6 7.1 6.2 0.21 10.6 0.1 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A DUF3602 PF12223.8 CAR21555.1 - 5.7e-19 68.5 11.9 5e-09 36.6 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 CAR21555.1 - 0.0064 16.1 3.7 1.4 8.5 0.1 3.1 3 0 0 3 3 3 2 GTP1/OBG eIF3_subunit PF08597.10 CAR21556.1 - 3.4e-53 181.0 15.2 4.3e-53 180.7 15.2 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FAD-oxidase_C PF02913.19 CAR21557.1 - 9.6e-60 202.3 0.1 2.3e-59 201.1 0.1 1.7 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAR21557.1 - 2.1e-36 124.7 0.0 6.1e-36 123.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain LEA_4 PF02987.16 CAR21558.1 - 0.00044 20.3 52.9 0.0046 17.0 13.8 5.0 2 1 1 4 4 4 3 Late embryogenesis abundant protein YtxH PF12732.7 CAR21558.1 - 0.0051 17.3 33.4 1.8e+04 -9.6 33.4 4.0 1 1 0 1 1 1 0 YtxH-like protein Trm5_N PF18093.1 CAR21558.1 - 0.027 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain DUF883 PF05957.13 CAR21558.1 - 0.028 15.0 28.5 0.18 12.4 8.4 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 CAR21558.1 - 0.033 14.3 15.8 0.033 14.3 15.8 2.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Borrelia_P83 PF05262.11 CAR21558.1 - 2.1 6.8 33.0 2.5 6.5 33.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein LAP1C PF05609.12 CAR21558.1 - 3.6 6.6 17.6 3.9 6.5 17.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peroxin-13_N PF04088.13 CAR21559.1 - 4e-46 156.9 1.9 5.6e-46 156.4 1.9 1.1 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 CAR21559.1 - 2.9e-09 36.5 0.0 1.6e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CAR21559.1 - 4.9e-09 35.9 0.2 1.4e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CAR21559.1 - 5.4e-08 32.3 0.0 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 CAR21559.1 - 0.00081 19.6 0.1 0.0032 17.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain Peptidase_C54 PF03416.19 CAR21559.1 - 0.05 13.0 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C54 Arfaptin PF06456.13 CAR21559.1 - 0.26 10.8 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 Arfaptin-like domain MMR1 PF08505.10 CAR21560.1 - 8.8e-63 213.0 11.4 8.8e-63 213.0 11.4 2.1 2 0 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein FlxA PF14282.6 CAR21560.1 - 0.0031 17.5 0.2 0.0031 17.5 0.2 3.3 3 0 0 3 3 3 1 FlxA-like protein Med9 PF07544.13 CAR21560.1 - 0.0045 17.0 4.5 0.0068 16.5 0.3 2.4 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 FapA PF03961.13 CAR21560.1 - 0.1 11.2 3.5 0.15 10.6 3.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HTH_46 PF15977.5 CAR21560.1 - 0.15 12.1 0.3 0.39 10.8 0.3 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA binding TMF_DNA_bd PF12329.8 CAR21560.1 - 0.61 10.1 11.8 0.097 12.7 3.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MIP-T3_C PF17749.1 CAR21560.1 - 0.62 10.0 10.6 0.76 9.7 4.5 2.5 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region CorA PF01544.18 CAR21560.1 - 0.63 9.3 5.9 1 8.6 5.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FlaC_arch PF05377.11 CAR21560.1 - 1.3 9.5 4.0 20 5.7 0.8 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 CAR21560.1 - 2.4 6.0 6.7 3.7 5.4 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 CAR21560.1 - 2.7 8.2 8.3 9.1 6.5 3.4 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF4407 PF14362.6 CAR21560.1 - 4.8 6.4 6.9 8.3 5.7 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 CAR21560.1 - 5.6 7.5 7.2 12 6.4 0.6 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PALP PF00291.25 CAR21561.1 - 1e-77 261.5 0.2 1.3e-77 261.1 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CAR21561.1 - 3.1e-40 135.8 0.0 1.4e-26 92.1 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase tRNA-synt_2b PF00587.25 CAR21562.1 - 8.9e-37 126.8 0.0 1.3e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CAR21562.1 - 0.0025 17.9 0.0 0.0059 16.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Sec61_beta PF03911.16 CAR21563.1 - 1.4e-17 63.4 0.7 1.7e-17 63.2 0.7 1.1 1 0 0 1 1 1 1 Sec61beta family RRM_1 PF00076.22 CAR21564.1 - 2.2e-06 27.4 0.1 5.1e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF390 PF04094.14 CAR21564.1 - 0.053 11.8 11.7 0.079 11.3 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) FSA_C PF10479.9 CAR21564.1 - 0.66 8.0 2.8 1.1 7.3 2.8 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ADH_N PF08240.12 CAR21565.1 - 2.1e-25 88.7 3.5 3.5e-25 88.0 3.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR21565.1 - 8.6e-20 71.0 0.0 1.3e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR21565.1 - 5e-08 34.1 0.0 7.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CAR21565.1 - 5.3e-05 22.6 0.1 9.9e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CAR21565.1 - 9.6e-05 21.8 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Hexapep_2 PF14602.6 CAR21565.1 - 0.031 14.0 0.6 0.07 12.9 0.6 1.6 1 0 0 1 1 1 0 Hexapeptide repeat of succinyl-transferase RseC_MucC PF04246.12 CAR21565.1 - 0.037 14.0 2.2 0.077 13.0 2.2 1.5 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC ApbA PF02558.16 CAR21565.1 - 0.085 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MOZ_SAS PF01853.18 CAR21566.1 - 4.6e-76 254.5 0.1 6.7e-76 253.9 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CAR21566.1 - 6.2e-20 70.6 7.7 1.7e-19 69.1 7.7 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain COX5B PF01215.19 CAR21566.1 - 0.043 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb Acetyltransf_7 PF13508.7 CAR21566.1 - 0.069 13.6 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.31 CAR21567.1 - 5.6e-11 42.4 1.2 5e-10 39.4 0.2 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR21567.1 - 1.7e-08 34.6 0.3 1.7e-08 34.6 0.3 2.1 2 1 0 2 2 2 1 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.6 CAR21568.1 - 2.2e-36 124.9 0.0 3.5e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 CAR21568.1 - 4.5e-05 23.2 0.1 0.001 18.8 0.1 2.1 1 1 0 1 1 1 1 Transposase DDE domain NMT1 PF09084.11 CAR21570.1 - 3.9e-12 46.6 0.0 4.8e-11 43.0 0.0 2.0 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CAR21570.1 - 3.3e-08 33.5 0.0 4.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 CAR21570.1 - 2e-07 30.7 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Phosphonate-bd PF12974.7 CAR21570.1 - 2.2e-05 24.2 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LysR_substrate PF03466.20 CAR21570.1 - 0.066 12.6 0.0 0.23 10.8 0.0 1.8 1 1 0 1 1 1 0 LysR substrate binding domain NMT1_3 PF16868.5 CAR21570.1 - 0.087 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family DCP2 PF05026.13 CAR21571.1 - 9.9e-26 89.9 1.8 1.5e-25 89.3 1.1 1.7 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 CAR21571.1 - 2.7e-12 46.9 0.0 7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain CTU2 PF10288.9 CAR21572.1 - 8.4e-20 71.1 0.4 2.1e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-CDGSH PF09360.10 CAR21572.1 - 0.072 13.3 1.5 0.2 11.9 0.2 2.4 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type CHCH PF06747.13 CAR21573.1 - 4.2e-05 23.5 10.3 6.4e-05 23.0 10.3 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 CAR21573.1 - 5.2e-05 23.4 3.9 7.5e-05 22.9 3.9 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 CAR21573.1 - 0.00051 20.3 4.4 0.00073 19.8 4.4 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 TPR_1 PF00515.28 CAR21574.1 - 2.3e-27 93.6 15.2 9e-07 28.5 0.2 10.0 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 CAR21574.1 - 4e-25 85.8 23.5 0.00052 19.9 0.1 11.8 10 1 1 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAR21574.1 - 3e-23 82.2 7.8 1.4e-05 25.6 0.1 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAR21574.1 - 2.2e-15 56.0 13.7 0.77 10.7 0.0 9.1 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAR21574.1 - 2.4e-14 52.3 22.3 0.00049 20.1 0.1 9.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAR21574.1 - 5e-14 52.6 17.5 8.8e-06 26.2 2.5 7.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAR21574.1 - 6.8e-13 48.7 13.9 0.0039 17.4 0.6 7.2 5 3 5 10 10 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR21574.1 - 2.2e-12 46.4 17.3 0.0026 17.4 0.1 8.1 6 2 2 8 8 8 3 TPR repeat TPR_9 PF13371.6 CAR21574.1 - 6.7e-08 32.6 0.3 0.84 9.8 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR21574.1 - 1.5e-06 28.2 10.7 0.54 10.8 0.0 8.2 7 2 2 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR21574.1 - 2.7e-06 27.5 8.8 0.024 14.8 0.1 4.4 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CAR21574.1 - 9.5e-05 21.9 0.8 0.0014 18.1 0.2 2.8 2 1 1 3 3 3 1 MalT-like TPR region TPR_15 PF13429.6 CAR21574.1 - 0.00093 18.5 2.6 0.071 12.3 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 CAR21574.1 - 0.0094 15.7 16.9 1.4 8.6 0.6 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain Exonuc_VII_S PF02609.16 CAR21574.1 - 0.011 15.7 0.7 0.011 15.7 0.7 2.7 2 0 0 2 2 2 0 Exonuclease VII small subunit PknG_TPR PF16918.5 CAR21574.1 - 0.053 12.3 0.1 9.2 4.9 0.0 2.3 1 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat MAS20 PF02064.15 CAR21574.1 - 0.096 12.8 3.7 0.22 11.6 2.0 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor TPR_20 PF14561.6 CAR21574.1 - 0.14 12.5 8.0 0.29 11.5 2.1 3.7 4 1 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 CAR21574.1 - 0.16 12.0 8.0 2.1 8.5 0.1 5.2 4 1 1 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CAR21574.1 - 0.29 11.1 13.5 3.4 7.7 0.3 6.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAR21574.1 - 0.46 11.2 21.9 8.9 7.2 0.5 8.4 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_3 PF07720.12 CAR21574.1 - 1.4 8.9 19.6 0.12 12.3 0.6 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR21574.1 - 2.4 8.4 13.8 0.9 9.7 0.3 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Sel1 PF08238.12 CAR21574.1 - 2.7 8.8 10.9 11 6.8 0.2 5.8 7 0 0 7 7 6 0 Sel1 repeat Ribosomal_L35p PF01632.19 CAR21576.1 - 9.9e-12 45.2 8.2 1.5e-11 44.6 8.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 PDZ_1 PF12812.7 CAR21577.1 - 4.5e-52 174.0 0.1 1.1e-34 118.2 0.0 2.8 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 CAR21577.1 - 4e-26 92.7 0.4 6.2e-21 75.9 0.0 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 CAR21577.1 - 3.2e-12 46.1 0.9 5.7e-07 29.3 0.2 4.3 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 CAR21577.1 - 4e-11 43.1 4.7 0.0022 18.3 0.1 4.6 5 0 0 5 5 5 2 PDZ domain PDZ PF00595.24 CAR21577.1 - 2.4e-10 40.6 0.0 4e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 PDZ domain Trypsin PF00089.26 CAR21577.1 - 0.00012 22.0 0.0 0.00045 20.1 0.0 2.0 2 0 0 2 2 2 1 Trypsin Tricorn_PDZ PF14685.6 CAR21577.1 - 0.0085 16.0 1.1 0.64 10.0 0.0 3.9 5 0 0 5 5 5 1 Tricorn protease PDZ domain DUF31 PF01732.16 CAR21577.1 - 0.019 14.5 0.1 0.03 13.9 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 CAR21577.1 - 0.034 14.0 0.1 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.9 CAR21577.1 - 0.094 11.3 0.4 0.2 10.2 0.1 1.6 2 0 0 2 2 2 0 Peptidase S46 ORC6 PF05460.13 CAR21578.1 - 4.2e-86 289.5 1.5 4.8e-86 289.3 1.5 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) N-SET PF11764.8 CAR21579.1 - 1.1e-45 155.8 1.8 1.1e-45 155.8 1.8 2.7 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 CAR21579.1 - 1.8e-19 70.8 7.9 4.5e-19 69.5 0.0 3.9 2 1 0 3 3 3 1 SET domain SET_assoc PF11767.8 CAR21579.1 - 6e-16 57.8 0.1 1.4e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated MutS_V PF00488.21 CAR21580.1 - 5.2e-67 225.5 0.0 1e-66 224.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR21580.1 - 2.2e-36 125.9 3.5 5e-36 124.7 3.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CAR21580.1 - 1.9e-27 95.7 0.0 5.8e-27 94.2 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CAR21580.1 - 2.9e-09 37.3 0.0 1.4e-08 35.1 0.0 2.3 2 0 0 2 2 2 1 MutS domain II AAA_14 PF13173.6 CAR21580.1 - 0.023 14.7 0.0 0.079 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CAR21580.1 - 0.06 13.8 1.3 0.39 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CAR21580.1 - 0.065 13.7 0.2 2 8.9 0.0 3.0 3 0 0 3 3 3 0 ABC transporter Gar1 PF04410.14 CAR21581.1 - 2.6e-46 157.2 0.1 1e-45 155.3 0.0 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Macoilin PF09726.9 CAR21581.1 - 0.32 9.5 12.5 0.35 9.4 4.0 2.1 2 0 0 2 2 2 0 Macoilin family GCP_C_terminal PF04130.13 CAR21582.1 - 3.6e-35 121.9 4.7 3.6e-35 121.9 4.7 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CAR21582.1 - 8.3e-35 120.9 7.4 9.9e-35 120.6 4.0 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Med7 PF05983.11 CAR21582.1 - 2.9 7.9 5.8 0.51 10.4 1.6 1.9 2 0 0 2 2 2 0 MED7 protein N1221 PF07923.13 CAR21583.1 - 6.3e-65 219.2 1.1 6.3e-65 219.2 1.1 2.0 3 0 0 3 3 3 1 N1221-like protein DUF3402 PF11882.8 CAR21583.1 - 4.7e-54 184.2 15.8 1.2e-29 103.8 4.8 3.8 2 1 1 3 3 3 2 Domain of unknown function (DUF3402) SWM_repeat PF13753.6 CAR21584.1 - 0.036 14.2 0.1 0.08 13.1 0.1 1.5 1 0 0 1 1 1 0 Putative flagellar system-associated repeat Glyco_hyd_101C PF17451.2 CAR21584.1 - 0.054 13.8 0.1 0.1 12.9 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DpnI PF06044.12 CAR21584.1 - 0.062 12.9 0.1 0.068 12.8 0.1 1.1 1 0 0 1 1 1 0 Dam-replacing family DSPc PF00782.20 CAR21585.1 - 3.5e-10 39.8 0.0 1.1e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR21585.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CAR21585.1 - 0.033 14.5 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 CAR21585.1 - 0.082 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CAR21585.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate PRK PF00485.18 CAR21586.1 - 2.2e-06 27.6 0.0 3.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CAR21586.1 - 3.5e-05 24.3 0.0 0.00018 22.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAR21586.1 - 0.0016 18.6 0.0 0.0034 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAR21586.1 - 0.04 14.3 0.0 0.05 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 CAR21586.1 - 0.054 13.7 0.1 0.31 11.3 0.2 2.0 2 0 0 2 2 2 0 AAA domain MOEP19 PF16005.5 CAR21586.1 - 0.081 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 KH-like RNA-binding domain Glyco_tranf_2_5 PF13712.6 CAR21586.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family CoaE PF01121.20 CAR21586.1 - 0.12 12.0 0.0 5.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_22 PF13401.6 CAR21586.1 - 0.13 12.6 0.0 0.23 11.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CAR21586.1 - 0.19 11.0 0.5 1.6 8.0 0.0 2.0 2 0 0 2 2 2 0 KaiC FeS_assembly_P PF01883.19 CAR21587.1 - 2e-08 34.3 0.0 4.6e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CDP-OH_P_transf PF01066.21 CAR21588.1 - 2.3e-16 60.3 0.0 2.3e-16 60.3 0.0 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Tom22 PF04281.13 CAR21589.1 - 4.5e-49 165.8 3.3 5.1e-49 165.6 3.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 GNAT_acetyltr_2 PF13718.6 CAR21590.1 - 3.6e-99 330.8 0.6 1.4e-98 328.8 0.0 2.2 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CAR21590.1 - 6.6e-93 310.7 4.5 1.8e-92 309.3 4.5 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CAR21590.1 - 1.5e-65 220.3 0.0 8.6e-65 217.9 0.0 2.3 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CAR21590.1 - 1.8e-34 117.6 0.9 4.3e-34 116.3 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 CAR21590.1 - 0.0033 17.2 0.0 0.088 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR21590.1 - 0.0057 16.9 0.0 0.84 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 CAR21590.1 - 0.022 14.5 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_19 PF13245.6 CAR21590.1 - 0.044 14.1 0.0 0.28 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NDT80_PhoG PF05224.12 CAR21591.1 - 1e-60 205.1 0.0 2e-60 204.2 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Nefa_Nip30_N PF10187.9 CAR21592.1 - 0.00022 21.5 16.5 0.00022 21.5 16.5 1.7 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 ADH_zinc_N PF00107.26 CAR21593.1 - 6.4e-16 58.5 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR21593.1 - 2.2e-05 25.5 0.0 3.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR21593.1 - 3.5e-05 23.6 0.3 0.00067 19.5 0.2 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain PIR PF00399.19 CAR21594.1 - 2.1e-07 30.3 9.5 2.1e-07 30.3 9.5 2.8 2 0 0 2 2 2 1 Yeast PIR protein repeat FKBP_C PF00254.28 CAR21595.1 - 4.1e-34 116.8 0.0 4.8e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Eaf7 PF07904.13 CAR21596.1 - 1.2e-31 109.3 0.3 1.2e-31 109.3 0.3 2.6 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 S4 PF01479.25 CAR21597.1 - 3e-16 58.8 0.0 5.9e-16 57.9 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 CAR21597.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain B PF02216.16 CAR21597.1 - 0.11 12.5 0.5 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 B domain LTXXQ PF07813.12 CAR21597.1 - 0.39 11.4 3.5 0.33 11.7 0.9 2.1 2 0 0 2 2 2 0 LTXXQ motif family protein Muted PF14942.6 CAR21597.1 - 5 7.4 7.9 4.5 7.6 0.3 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Fmp27_SW PF10305.9 CAR21597.1 - 8.1 7.2 7.3 3.1 8.6 1.7 2.9 3 1 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain CAP_N PF01213.19 CAR21598.1 - 9.4e-111 370.3 3.7 9.4e-111 370.3 3.7 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CAR21598.1 - 1.6e-58 196.8 3.4 1.6e-58 196.8 3.4 1.9 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CAR21598.1 - 0.0047 16.6 2.0 0.0091 15.7 2.0 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Fib_alpha PF08702.10 CAR21598.1 - 0.0079 16.4 1.1 0.016 15.4 0.1 1.9 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF3060 PF11259.8 CAR21598.1 - 0.061 13.0 2.7 0.97 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3060) PRIMA1 PF16101.5 CAR21598.1 - 2.9 8.0 11.7 2.4 8.2 4.4 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SF3b10 PF07189.11 CAR21600.1 - 4.7e-25 87.5 0.9 5.6e-25 87.3 0.9 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) THOC2_N PF16134.5 CAR21601.1 - 7e-143 477.5 11.0 1.2e-142 476.7 10.2 1.8 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CAR21601.1 - 4.6e-34 118.0 4.3 4.6e-34 118.0 4.3 3.3 2 1 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CAR21601.1 - 1.7e-20 72.9 0.7 6.7e-20 70.9 0.3 2.4 2 0 0 2 2 2 1 Transcription- and export-related complex subunit HWE_HK PF07536.14 CAR21601.1 - 0.13 13.0 0.9 1.1 10.1 0.1 3.1 2 0 0 2 2 2 0 HWE histidine kinase Sld5 PF05916.11 CAR21601.1 - 2.2 8.8 7.7 19 5.8 0.3 3.7 3 0 0 3 3 3 0 GINS complex protein C2 PF00168.30 CAR21602.1 - 6.3e-10 39.3 0.0 1.3e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain RNA_pol_3_Rpc31 PF11705.8 CAR21603.1 - 2.7e-51 175.0 6.7 4.1e-51 174.4 6.7 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PGA2 PF07543.12 CAR21604.1 - 9.9e-15 54.7 8.2 3.9e-12 46.3 8.2 2.0 1 1 0 1 1 1 1 Protein trafficking PGA2 Mit_KHE1 PF10173.9 CAR21604.1 - 0.13 12.3 1.3 0.16 12.0 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ATP-synt_E PF05680.12 CAR21604.1 - 0.29 11.5 5.2 0.82 10.0 0.5 2.1 2 0 0 2 2 2 0 ATP synthase E chain COX16 PF14138.6 CAR21604.1 - 0.38 11.3 5.4 1.5 9.4 5.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 CAP_GLY PF01302.25 CAR21605.1 - 1.7e-18 66.3 0.1 2.4e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CAR21605.1 - 1.4e-07 31.9 0.1 3.2e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-like domain LSM PF01423.22 CAR21606.1 - 1.5e-19 69.4 0.3 1.9e-19 69.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain UPRTase PF14681.6 CAR21607.1 - 1.5e-77 259.7 0.0 1.9e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CoA_binding_2 PF13380.6 CAR21607.1 - 0.008 16.7 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain Pribosyltran PF00156.27 CAR21607.1 - 0.019 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 CAR21607.1 - 0.17 11.8 0.2 0.36 10.8 0.2 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.19 CAR21608.1 - 1.8e-116 389.1 0.0 1e-115 386.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAR21608.1 - 9.5e-05 21.4 0.0 0.005 15.7 0.0 2.0 2 0 0 2 2 2 2 MreB/Mbl protein DUF2009 PF09418.10 CAR21609.1 - 7.3e-210 697.8 0.1 9e-210 697.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CAR21609.1 - 0.00011 22.3 6.9 0.00019 21.5 6.9 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CAR21609.1 - 0.0063 16.7 5.4 0.015 15.6 5.4 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain PolC_DP2 PF03833.13 CAR21609.1 - 0.81 7.5 5.6 0.25 9.2 3.0 1.4 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 IBR PF01485.21 CAR21609.1 - 2.4 8.5 10.8 5.8 7.2 8.9 2.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Tnp_zf-ribbon_2 PF13842.6 CAR21609.1 - 4.2 8.2 7.2 8.5 7.3 7.2 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon YqbF PF14553.6 CAR21610.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Arginase PF00491.21 CAR21611.1 - 3.8e-88 295.6 0.0 5e-88 295.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CAR21611.1 - 0.0086 16.3 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 UPF0489 domain Pga1 PF10333.9 CAR21613.1 - 7.5e-52 175.7 0.0 8.5e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Peptidase_M14 PF00246.24 CAR21614.1 - 2e-75 254.3 0.0 2.4e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Endosulfine PF04667.17 CAR21615.1 - 5.2e-30 103.4 0.5 7.2e-30 103.0 0.5 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.12 CAR21616.1 - 3.9e-19 69.1 7.9 1.1e-16 61.2 7.9 2.8 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF202 PF02656.15 CAR21616.1 - 3.5 8.1 7.4 6.9 7.2 5.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) WLM PF08325.10 CAR21617.1 - 3.6e-55 187.0 1.5 1.8e-54 184.7 1.5 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 CAR21617.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 zf-AN1 PF01428.16 CAR21618.1 - 1.3e-10 41.2 12.1 2.6e-10 40.3 12.1 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger FYVE PF01363.21 CAR21618.1 - 0.0096 16.0 3.1 0.019 15.1 3.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Epimerase PF01370.21 CAR21619.1 - 3e-14 53.1 0.0 4.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR21619.1 - 1.8e-12 46.9 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CAR21619.1 - 1.9e-10 40.6 0.0 2.7e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR21619.1 - 2.5e-09 36.7 0.0 3.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 CAR21619.1 - 2.8e-08 33.9 0.0 7.7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CAR21619.1 - 8e-08 32.4 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CAR21619.1 - 0.00062 19.3 0.0 0.0025 17.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CAR21619.1 - 0.038 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 CAR21620.1 - 1.1e-24 87.2 0.0 1.1e-24 87.2 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21620.1 - 4.8e-13 49.0 0.5 2.1e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR21620.1 - 1.5e-09 37.1 0.0 1.5e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Exonuc_VII_L PF02601.15 CAR21620.1 - 0.25 10.9 18.6 0.38 10.3 18.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GREB1 PF15782.5 CAR21620.1 - 2 5.4 20.2 2.6 5.0 20.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SID-1_RNA_chan PF13965.6 CAR21620.1 - 6 5.2 6.3 7.6 4.8 6.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 A_deaminase PF00962.22 CAR21621.1 - 2.4e-84 283.5 0.0 2.8e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Cas_Csa5 PF09702.10 CAR21622.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) Aminotran_1_2 PF00155.21 CAR21623.1 - 2.6e-15 56.5 0.0 3.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CAR21623.1 - 0.064 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase FAM184 PF15665.5 CAR21623.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Prefoldin_2 PF01920.20 CAR21624.1 - 2.9e-23 81.8 9.8 3.5e-23 81.6 9.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Med4 PF10018.9 CAR21624.1 - 0.0087 15.8 2.0 0.0087 15.8 2.0 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Nop16 PF09420.10 CAR21624.1 - 0.011 15.8 2.4 0.014 15.4 2.4 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Spc7 PF08317.11 CAR21624.1 - 0.02 13.8 7.3 0.023 13.6 7.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5082 PF16888.5 CAR21624.1 - 0.028 14.7 1.6 0.028 14.7 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) ABC_tran_CTD PF16326.5 CAR21624.1 - 0.067 13.5 1.3 0.067 13.5 1.3 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain RSS_P20 PF11757.8 CAR21624.1 - 0.075 13.5 1.4 0.42 11.1 0.1 2.1 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Seryl_tRNA_N PF02403.22 CAR21624.1 - 0.46 10.7 9.6 4 7.7 1.0 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4140 PF13600.6 CAR21624.1 - 8 7.0 7.6 1.5e+02 2.9 7.6 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CstA PF02554.14 CAR21625.1 - 0.054 12.4 0.0 0.059 12.3 0.0 1.0 1 0 0 1 1 1 0 Carbon starvation protein CstA Trep_dent_lipo PF09710.10 CAR21625.1 - 0.078 11.9 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Ammonium_transp PF00909.21 CAR21626.1 - 8.8e-127 423.1 27.0 1e-126 422.9 27.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Far-17a_AIG1 PF04750.14 CAR21627.1 - 1.4e-13 50.6 1.4 1.8e-13 50.3 1.4 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Asparaginase_C PF17763.1 CAR21628.1 - 0.00088 19.5 0.3 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Asparaginase PF00710.20 CAR21628.1 - 0.0038 16.8 0.5 0.015 14.9 0.2 2.0 2 1 0 2 2 2 1 Asparaginase, N-terminal Epimerase PF01370.21 CAR21629.1 - 1.6e-16 60.5 0.0 2.3e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR21629.1 - 1.1e-11 44.2 0.0 1.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CAR21629.1 - 5e-08 33.1 0.0 7.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CAR21629.1 - 5.7e-07 29.2 0.8 1.6e-06 27.7 0.8 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CAR21629.1 - 0.00018 21.5 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CAR21629.1 - 0.0002 20.6 0.1 0.00034 19.8 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CAR21629.1 - 0.00067 18.9 0.0 0.0027 16.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CAR21629.1 - 0.0067 15.9 0.2 0.026 14.0 0.0 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.24 CAR21629.1 - 0.015 15.7 0.0 0.056 13.9 0.0 2.0 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 CAR21629.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 CAR21629.1 - 0.032 13.8 0.1 0.073 12.6 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family Pkinase PF00069.25 CAR21630.1 - 6.2e-62 209.4 0.2 6.8e-42 143.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21630.1 - 4.8e-27 94.9 0.3 1.7e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR21630.1 - 2.4e-05 23.4 0.2 3.9e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR21630.1 - 0.002 17.5 0.0 0.0059 16.0 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR21630.1 - 0.0047 16.9 0.1 0.67 9.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAR21630.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CAR21630.1 - 0.037 13.3 0.2 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Kinase-like TFIIA PF03153.13 CAR21630.1 - 2 8.3 11.7 3.7 7.4 11.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L44 PF00935.19 CAR21631.1 - 7.5e-35 119.2 10.7 1.2e-34 118.6 10.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Chs7 PF12271.8 CAR21632.1 - 4.3e-115 384.0 17.5 4.9e-115 383.8 17.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Lar_restr_allev PF14354.6 CAR21633.1 - 0.042 14.2 4.1 0.05 14.0 4.1 1.3 1 1 0 1 1 1 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 CAR21633.1 - 0.071 13.0 1.8 0.094 12.7 1.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain GTP_EFTU PF00009.27 CAR21634.1 - 1.5e-57 194.3 0.0 2.4e-57 193.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CAR21634.1 - 2.7e-14 53.0 0.1 1.2e-13 50.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR21634.1 - 1.6e-09 38.0 0.0 4.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CAR21634.1 - 9.4e-08 32.0 0.0 2.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CAR21634.1 - 0.0067 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CAR21634.1 - 0.029 14.5 0.0 0.082 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase eRF1_1 PF03463.15 CAR21636.1 - 0.25 11.3 0.1 0.25 11.3 0.1 2.9 2 2 1 3 3 3 0 eRF1 domain 1 SPX PF03105.19 CAR21636.1 - 6.3 6.6 27.6 9.9 6.0 27.6 1.4 1 0 0 1 1 1 0 SPX domain Nup54 PF13874.6 CAR21638.1 - 0.036 14.2 0.4 0.036 14.2 0.4 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Macoilin PF09726.9 CAR21638.1 - 9.5 4.6 11.0 0.74 8.3 6.2 1.5 2 0 0 2 2 2 0 Macoilin family DNA_RNApol_7kD PF03604.13 CAR21639.1 - 1.1e-16 60.2 1.7 1.4e-16 59.9 1.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 CAR21639.1 - 0.004 16.7 0.8 1.5 8.5 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 CAR21639.1 - 0.0066 16.4 0.3 0.0089 16.0 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon TFIIS_C PF01096.18 CAR21639.1 - 0.01 15.7 0.7 3.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) HypA PF01155.19 CAR21639.1 - 0.012 15.6 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 CAR21639.1 - 0.019 14.9 0.4 0.025 14.6 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons MCM_OB PF17207.3 CAR21639.1 - 0.029 14.2 0.2 0.032 14.1 0.2 1.1 1 0 0 1 1 1 0 MCM OB domain Ribosomal_L40e PF01020.17 CAR21639.1 - 0.037 13.9 2.3 0.053 13.4 2.3 1.3 1 0 0 1 1 1 0 Ribosomal L40e family zinc_ribbon_10 PF10058.9 CAR21639.1 - 0.052 13.3 0.2 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4428 PF14471.6 CAR21639.1 - 0.09 12.7 1.5 1.5 8.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF2197 PF09963.9 CAR21639.1 - 0.094 13.0 2.0 7.4 6.9 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn_ribbon_SprT PF17283.2 CAR21639.1 - 0.1 12.5 2.5 0.15 12.0 1.8 1.7 1 1 2 3 3 3 0 SprT-like zinc ribbon domain FYDLN_acid PF09538.10 CAR21639.1 - 0.14 12.9 0.4 0.15 12.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 CAR21639.1 - 0.2 11.8 3.0 0.69 10.1 2.9 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 CAR21639.1 - 0.26 11.8 2.9 3.7 8.1 0.6 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Rubredoxin_2 PF18073.1 CAR21639.1 - 0.54 10.0 2.7 9.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribosomal_L44 PF00935.19 CAR21639.1 - 1.6 9.3 5.0 13 6.3 0.7 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 DUP PF00674.18 CAR21640.1 - 1.7e-11 44.2 0.0 1.9e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 DUP family DUP PF00674.18 CAR21641.1 - 2.7e-26 91.7 0.0 7.7e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 DUP family bZIP_1 PF00170.21 CAR21642.1 - 1.9e-07 31.1 3.7 4.3e-07 29.9 3.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 CAR21642.1 - 7.3e-06 26.3 0.4 7.3e-06 26.3 0.4 5.9 4 2 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 CAR21642.1 - 0.00011 22.3 5.6 0.00011 22.3 5.6 2.6 2 0 0 2 2 2 1 Basic region leucine zipper FAA_hydrolase PF01557.18 CAR21643.1 - 3.8e-48 164.0 0.0 5e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family dCMP_cyt_deam_1 PF00383.23 CAR21644.1 - 3.7e-26 90.9 2.5 5.6e-26 90.4 2.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR21644.1 - 2.8e-14 53.0 0.1 4.3e-14 52.5 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase PS_Dcarbxylase PF02666.15 CAR21645.1 - 3.6e-69 232.3 0.0 1e-68 230.8 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ANAPC1 PF12859.7 CAR21646.1 - 1.8e-10 41.4 1.7 9e-10 39.2 1.3 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 AMPK1_CBM PF16561.5 CAR21647.1 - 7e-18 64.6 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase RRM_1 PF00076.22 CAR21648.1 - 2.5e-24 84.9 0.3 5.7e-17 61.3 0.1 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR21648.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CAR21648.1 - 0.056 13.6 0.1 1.6 8.9 0.0 2.7 2 2 0 2 2 2 0 RNA recognition motif Mid2 PF04478.12 CAR21649.1 - 0.00012 21.9 0.0 0.00012 21.9 0.0 2.8 2 1 2 4 4 4 1 Mid2 like cell wall stress sensor CD34_antigen PF06365.12 CAR21649.1 - 0.022 14.4 0.1 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family Orf78 PF06024.12 CAR21649.1 - 0.12 12.7 0.0 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 Orf78 (ac78) PIRT PF15099.6 CAR21649.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.5 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family Adeno_E3_CR2 PF02439.15 CAR21649.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3793 PF12672.7 CAR21649.1 - 0.19 11.7 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Ribosomal_L22 PF00237.19 CAR21650.1 - 1.4e-21 76.7 0.4 3.3e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e SHR3_chaperone PF08229.11 CAR21651.1 - 3.5e-75 251.1 0.9 4.3e-75 250.8 0.9 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF1072 PF06380.11 CAR21651.1 - 0.071 13.0 0.1 9.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) COX14 PF14880.6 CAR21651.1 - 0.15 11.9 3.6 0.24 11.2 0.9 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Ribosomal_S3_C PF00189.20 CAR21652.1 - 4.2e-23 81.7 0.7 2.2e-22 79.4 0.4 2.2 3 0 0 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CAR21652.1 - 2.6e-12 46.4 0.1 1.3e-11 44.2 0.1 2.0 2 0 0 2 2 2 1 KH domain Ras PF00071.22 CAR21653.1 - 9.9e-47 158.5 0.0 1.4e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR21653.1 - 6.8e-21 74.7 0.0 3.8e-20 72.3 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR21653.1 - 2e-06 27.4 0.0 3.2e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR21653.1 - 0.003 17.6 0.0 0.0044 17.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR21653.1 - 0.01 15.4 0.0 0.041 13.4 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain adh_short PF00106.25 CAR21654.1 - 1.7e-11 43.9 0.0 3.3e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR21654.1 - 7.8e-09 35.4 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR21654.1 - 1e-07 32.0 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 KR domain DUF1768 PF08719.11 CAR21654.1 - 0.025 14.8 0.2 0.045 14.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) DUF4454 PF14628.6 CAR21654.1 - 0.048 13.5 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) ANAPC4_WD40 PF12894.7 CAR21655.1 - 0.01 16.1 0.1 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CAR21655.1 - 0.022 14.0 0.1 1.5 8.0 0.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 CAR21655.1 - 0.027 15.3 0.0 7.3 7.6 0.0 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat HPS3_N PF14761.6 CAR21655.1 - 0.16 11.5 1.0 16 4.9 0.0 3.0 3 1 1 4 4 4 0 Hermansky-Pudlak syndrome 3 SNRNP27 PF08648.12 CAR21656.1 - 6e-14 51.9 0.5 1.3e-13 50.7 0.5 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins RRM_1 PF00076.22 CAR21657.1 - 5.8e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CAR21658.1 - 2.4e-50 171.4 0.0 5.6e-50 170.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21658.1 - 1.4e-24 86.8 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR21658.1 - 0.0037 16.2 0.1 0.0087 15.0 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAR21658.1 - 0.013 14.8 0.1 0.07 12.4 0.3 1.9 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 CAR21658.1 - 0.057 13.0 0.2 1.7 8.2 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAR21658.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.14 CAR21659.1 - 3.1e-26 91.0 0.4 5.8e-26 90.1 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CAR21659.1 - 1.7e-23 82.9 0.2 3.3e-23 82.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain MIF PF01187.18 CAR21659.1 - 0.081 13.2 0.0 2.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) UCH PF00443.29 CAR21660.1 - 1.9e-49 168.5 1.9 3.2e-49 167.8 1.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR21660.1 - 3.6e-18 66.2 5.5 6.6e-17 62.1 5.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-BED PF02892.15 CAR21660.1 - 0.11 12.5 0.8 7.1 6.7 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger Prenyltrans PF00432.21 CAR21660.1 - 0.12 12.2 0.9 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Peptidase_C98 PF15499.6 CAR21660.1 - 0.48 9.9 2.3 5.8 6.3 2.3 2.3 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase ELFV_dehydrog PF00208.21 CAR21661.1 - 2.2e-63 214.3 0.0 5e-63 213.1 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CAR21661.1 - 4.9e-19 67.5 0.0 6.4e-10 37.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CAR21661.1 - 9.9e-05 22.2 0.0 0.00043 20.2 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Dcc1 PF09724.9 CAR21661.1 - 0.0032 16.8 0.2 0.032 13.5 0.2 2.2 2 0 0 2 2 2 1 Sister chromatid cohesion protein Dcc1 Phage_int_SAM_4 PF13495.6 CAR21661.1 - 0.1 13.1 0.1 0.48 10.9 0.1 2.2 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain JAB PF01398.21 CAR21662.1 - 1.7e-29 102.2 0.1 3.6e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 CAR21662.1 - 2.3e-05 24.5 0.1 6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) Prok-JAB PF14464.6 CAR21662.1 - 8.2e-05 22.4 0.0 0.00029 20.6 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain WD40 PF00400.32 CAR21663.1 - 0.023 15.6 2.9 79 4.4 0.0 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat PAS_5 PF07310.13 CAR21663.1 - 0.04 13.7 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 PAS domain Tim17 PF02466.19 CAR21664.1 - 8.3e-40 135.6 1.9 1e-39 135.3 1.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.18 CAR21664.1 - 0.078 12.5 0.4 0.33 10.5 0.0 2.0 2 1 0 2 2 2 0 Dienelactone hydrolase family Serine_protease PF18405.1 CAR21664.1 - 0.17 11.0 0.1 0.28 10.3 0.1 1.3 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Gly-zipper_Omp PF13488.6 CAR21664.1 - 1 9.4 7.1 0.44 10.6 0.5 2.2 2 0 0 2 2 2 0 Glycine zipper Arm PF00514.23 CAR21666.1 - 3.1e-84 274.7 19.2 2.4e-12 46.4 0.3 8.7 9 0 0 9 9 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CAR21666.1 - 6.6e-29 100.2 7.7 2.2e-28 98.6 6.8 2.4 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 CAR21666.1 - 4.5e-22 77.4 2.9 5.7e-21 73.8 3.5 2.4 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 CAR21666.1 - 1.8e-21 76.2 1.6 3.2e-06 27.5 0.0 7.2 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 CAR21666.1 - 4.1e-14 52.7 0.1 0.0028 18.0 0.0 5.1 1 1 5 7 7 7 6 HEAT repeats HEAT PF02985.22 CAR21666.1 - 1.4e-12 46.7 0.0 0.055 13.7 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat V-ATPase_H_C PF11698.8 CAR21666.1 - 8.9e-06 25.8 2.2 0.22 11.6 0.0 4.7 3 1 4 7 7 7 3 V-ATPase subunit H Arm_2 PF04826.13 CAR21666.1 - 1.3e-05 24.9 0.8 0.83 9.1 0.0 4.2 3 1 1 4 4 4 2 Armadillo-like RICTOR_V PF14668.6 CAR21666.1 - 0.00014 22.0 4.7 0.14 12.4 0.0 4.8 3 3 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 CAR21666.1 - 0.0002 20.1 0.9 0.0051 15.4 0.5 2.6 1 1 1 2 2 2 2 Adaptin N terminal region NopRA1 PF16201.5 CAR21666.1 - 0.0036 16.9 0.1 10 5.6 0.0 4.7 1 1 3 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Atx10homo_assoc PF09759.9 CAR21666.1 - 0.031 14.3 0.8 5.7 7.0 0.0 4.0 4 1 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain PUL PF08324.11 CAR21666.1 - 0.32 10.2 4.4 0.34 10.1 0.1 2.6 2 1 1 3 3 3 0 PUL domain SAPS PF04499.15 CAR21666.1 - 0.65 8.7 5.2 0.25 10.1 0.6 2.3 2 1 1 3 3 3 0 SIT4 phosphatase-associated protein 7TMR-HDED PF07697.11 CAR21666.1 - 1.8 8.6 12.6 0.16 12.1 6.5 2.2 2 1 0 2 2 2 0 7TM-HD extracellular SspP PF08179.12 CAR21667.1 - 0.00035 21.0 5.3 75 3.9 0.0 5.3 5 0 0 5 5 5 0 Small acid-soluble spore protein P family HTH_56 PF18662.1 CAR21667.1 - 0.047 13.8 2.1 0.67 10.0 0.0 3.2 1 1 5 6 6 6 0 Cch helix turn helix domain Gmad2 PF10648.9 CAR21667.1 - 0.28 11.5 8.6 7.1 6.9 0.2 4.3 1 1 5 6 6 6 0 Immunoglobulin-like domain of bacterial spore germination MARVEL PF01284.23 CAR21668.1 - 1.3e-25 90.1 7.1 1.7e-25 89.8 7.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain CD52 PF15116.6 CAR21668.1 - 0.015 15.4 2.0 0.03 14.4 0.1 2.3 2 0 0 2 2 2 0 CAMPATH-1 antigen GATase_4 PF13230.6 CAR21669.1 - 1.8e-16 59.9 0.0 1.5e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 CAR21669.1 - 5.9e-11 42.7 0.0 9.8e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CAR21669.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 2 0 0 2 2 2 0 Glutamine amidotransferase domain Tyr_Deacylase PF02580.16 CAR21670.1 - 1.5e-50 171.5 0.1 1.6e-50 171.3 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF1661 PF07877.11 CAR21670.1 - 0.2 11.3 0.1 0.57 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1661) Chitin_synth_1 PF01644.17 CAR21671.1 - 1.1e-67 227.1 0.0 2e-67 226.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CAR21671.1 - 6.8e-28 96.4 0.1 1.7e-27 95.2 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CAR21671.1 - 3.8e-16 58.8 6.8 1.3e-12 47.1 0.0 2.6 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CAR21671.1 - 8e-10 39.0 3.9 8e-10 39.0 3.9 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CAR21671.1 - 0.0088 15.9 0.0 4 7.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CAR21671.1 - 0.024 14.5 0.0 0.086 12.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF2207 PF09972.9 CAR21671.1 - 0.049 12.4 0.1 0.049 12.4 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CDC13_N PF16853.5 CAR21673.1 - 4.1e-73 245.4 4.0 7.4e-73 244.5 4.0 1.4 1 0 0 1 1 1 1 Cell division control protein 13 N-terminus Cdc13_OB4_dimer PF18233.1 CAR21673.1 - 2.7e-23 82.3 0.0 6e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Cdc13 OB4 dimerization domain Cdc13_OB2 PF18691.1 CAR21673.1 - 0.0051 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Cell division control protein 13, OB2 domain SUR7 PF06687.12 CAR21674.1 - 3.3e-41 141.3 9.1 4.4e-41 140.9 9.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF3671 PF12420.8 CAR21674.1 - 0.078 13.1 0.5 13 6.0 1.0 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF21 PF01595.20 CAR21674.1 - 2.4 7.8 7.5 2.9 7.6 0.0 2.4 3 0 0 3 3 3 0 Cyclin M transmembrane N-terminal domain RNA_pol_Rpb2_5 PF04567.17 CAR21676.1 - 0.054 14.1 0.2 0.095 13.3 0.2 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 5 RRM_1 PF00076.22 CAR21677.1 - 5.2e-17 61.4 0.0 1.5e-15 56.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_34 PF13872.6 CAR21677.1 - 0.055 12.3 0.3 0.11 11.3 0.3 1.5 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF3740 PF12548.8 CAR21677.1 - 0.7 10.3 7.4 1.6 9.1 3.5 2.3 2 0 0 2 2 2 0 Sulfatase protein RR_TM4-6 PF06459.12 CAR21677.1 - 3 7.6 15.1 4.6 7.0 7.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CAR21677.1 - 6.4 6.2 16.5 2.7 7.4 9.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CAR21677.1 - 8.9 5.0 21.4 5.8 5.6 12.3 2.1 2 0 0 2 2 2 0 Presenilin Septin PF00735.18 CAR21678.1 - 4.7e-74 249.2 2.3 1.4e-66 224.7 0.5 2.5 3 0 0 3 3 3 2 Septin AAA_24 PF13479.6 CAR21678.1 - 0.00018 21.3 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR21678.1 - 0.0035 17.6 0.0 0.017 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.16 CAR21678.1 - 0.01 15.2 2.0 0.4 10.0 0.0 3.1 4 0 0 4 4 4 0 AIG1 family AAA_33 PF13671.6 CAR21678.1 - 0.011 15.9 0.0 0.043 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAR21678.1 - 0.016 14.7 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CAR21678.1 - 0.02 15.3 1.1 0.18 12.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CAR21678.1 - 0.03 14.4 3.0 0.071 13.2 0.0 2.9 3 1 0 3 3 3 0 Dynamin family Pox_A32 PF04665.12 CAR21678.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 CAR21678.1 - 0.051 13.5 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 CAR21678.1 - 0.061 13.3 0.0 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CAR21678.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CAR21678.1 - 0.12 12.4 0.0 0.42 10.6 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CAR21678.1 - 0.19 12.2 1.2 0.64 10.5 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CAR21678.1 - 0.19 11.6 1.5 0.9 9.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain LMBR1 PF04791.16 CAR21678.1 - 0.89 8.4 2.3 1 8.2 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF737 PF05300.11 CAR21678.1 - 7.7 6.8 19.9 31 4.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF737) YjeF_N PF03853.15 CAR21680.1 - 1e-33 116.6 0.0 1.2e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus T2SSE_N PF05157.15 CAR21680.1 - 0.17 12.2 0.0 13 6.1 0.0 2.8 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein E, N-terminal domain SMK-1 PF04802.15 CAR21681.1 - 5e-64 215.7 3.8 5e-64 215.7 3.8 3.4 3 1 0 3 3 3 1 Component of IIS longevity pathway SMK-1 ANTAR PF03861.14 CAR21681.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 ANTAR domain adh_short_C2 PF13561.6 CAR21682.1 - 1.2e-44 152.6 0.3 1.5e-44 152.3 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR21682.1 - 2.5e-32 112.0 1.4 9.5e-32 110.0 1.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR21682.1 - 4.6e-08 33.2 0.9 1.1e-07 32.0 0.4 1.7 2 0 0 2 2 2 1 KR domain ArfGap PF01412.18 CAR21683.1 - 4e-32 110.8 0.0 1.1e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3482 PF11981.8 CAR21683.1 - 0.00065 19.2 1.0 0.0015 18.0 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3482) Topoisom_I_N PF02919.15 CAR21683.1 - 0.93 9.0 4.6 1.4 8.3 4.6 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PH_18 PF18469.1 CAR21684.1 - 1.2e-48 164.7 0.6 1.9e-48 164.0 0.1 1.6 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106 PF08512.12 CAR21684.1 - 1.2e-27 96.1 1.3 2.5e-27 95.1 0.3 2.0 2 1 0 2 2 2 1 Histone chaperone Rttp106-like Rtt106_N PF18215.1 CAR21684.1 - 8.6e-06 25.4 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain Glypican PF01153.19 CAR21684.1 - 7 5.4 7.9 9.8 4.9 7.9 1.2 1 0 0 1 1 1 0 Glypican RIO1 PF01163.22 CAR21685.1 - 3.8e-41 140.8 0.1 7.8e-41 139.7 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CAR21685.1 - 1.6e-32 111.5 0.1 3.5e-32 110.5 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CAR21685.1 - 2.1e-08 34.4 0.2 0.0061 16.5 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CAR21685.1 - 0.0015 17.9 0.0 0.04 13.3 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rox3 PF08633.10 CAR21685.1 - 4.2 7.6 10.0 8.5 6.6 10.0 1.4 1 0 0 1 1 1 0 Rox3 mediator complex subunit HSP70 PF00012.20 CAR21686.1 - 1.3e-231 769.9 9.9 1.5e-231 769.8 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR21686.1 - 6.1e-17 61.4 0.7 1.1e-15 57.3 0.3 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CAR21686.1 - 0.32 11.4 9.6 1.7 9.1 0.1 3.8 3 3 0 3 3 3 0 Cell division protein FtsA KH_1 PF00013.29 CAR21687.1 - 9e-07 28.6 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CAR21687.1 - 0.078 12.8 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 KH domain Y_phosphatase PF00102.27 CAR21688.1 - 2.1e-55 187.9 0.3 6.2e-55 186.3 0.3 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CAR21688.1 - 0.00059 19.9 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CAR21688.1 - 0.0032 17.3 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CAR21688.1 - 0.035 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate FUSC_2 PF13515.6 CAR21689.1 - 5.4e-08 33.0 25.4 1.4e-06 28.5 6.4 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 CAR21689.1 - 4.9e-07 29.1 21.6 2e-06 27.2 5.9 3.6 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 CAR21689.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Mrx7 PF10906.8 CAR21690.1 - 8.2e-28 96.5 0.3 1e-27 96.2 0.3 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 VID27 PF08553.10 CAR21691.1 - 5.4e-156 519.1 3.9 7e-156 518.7 3.9 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CAR21691.1 - 8.9e-48 162.4 0.1 8.9e-48 162.4 0.1 3.0 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 CAR21691.1 - 7.6e-28 97.0 0.4 4.2e-27 94.6 0.5 2.2 2 0 0 2 2 2 1 VID27 PH-like domain WD40 PF00400.32 CAR21691.1 - 0.014 16.2 0.0 0.92 10.5 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Neugrin PF06413.11 CAR21692.1 - 6.5e-14 52.5 3.6 6.5e-14 52.5 3.6 1.4 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 CAR21692.1 - 0.0016 18.6 4.8 0.0026 18.0 4.8 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 CAR21692.1 - 0.011 16.3 0.3 0.011 16.3 0.3 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.12 CAR21692.1 - 0.012 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 HTH domain Sigma70_r4 PF04545.16 CAR21692.1 - 0.11 12.1 0.3 0.21 11.1 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 CDPS PF16715.5 CAR21693.1 - 0.038 13.6 0.1 0.058 13.0 0.1 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase DUF2951 PF11166.8 CAR21693.1 - 0.13 12.5 0.7 1.2 9.4 0.4 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) LIM_bind PF01803.16 CAR21694.1 - 6.6e-65 219.0 0.0 6.6e-65 219.0 0.0 1.8 2 0 0 2 2 2 1 LIM-domain binding protein PAPA-1 PF04795.12 CAR21695.1 - 2.9e-18 66.4 10.2 2.9e-18 66.4 10.2 2.7 2 1 0 2 2 2 1 PAPA-1-like conserved region Lipl32 PF12103.8 CAR21695.1 - 1.4 8.6 4.1 1.2 8.8 2.5 1.7 1 1 1 2 2 2 0 Surface lipoprotein of Spirochaetales order EMC3_TMCO1 PF01956.16 CAR21695.1 - 7.4 6.3 4.8 12 5.6 4.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like RabGAP-TBC PF00566.18 CAR21696.1 - 1.2e-31 110.1 20.8 8.5e-29 100.7 20.8 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Rap1-DNA-bind PF09197.10 CAR21697.1 - 3.3e-46 156.4 1.3 3e-42 143.6 0.2 2.8 2 0 0 2 2 2 2 Rap1, DNA-binding Rap1_C PF11626.8 CAR21697.1 - 4.6e-23 81.1 0.0 4e-22 78.1 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 CAR21697.1 - 2.9e-14 53.2 0.0 2.4e-13 50.3 0.0 2.6 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 CAR21697.1 - 1e-13 51.2 0.4 4.6e-11 42.7 0.0 4.4 4 1 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 CAR21697.1 - 1.3e-08 34.8 0.6 6.6e-05 23.0 0.0 2.9 3 0 0 3 3 3 2 Rap1 Myb domain BRCT PF00533.26 CAR21697.1 - 0.00024 21.4 0.4 0.0016 18.8 0.0 2.7 3 1 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_6 PF13921.6 CAR21697.1 - 0.027 14.7 0.2 0.64 10.3 0.0 2.8 2 1 0 2 2 2 0 Myb-like DNA-binding domain SLIDE PF09111.10 CAR21697.1 - 0.038 14.0 0.1 0.21 11.6 0.0 2.2 2 0 0 2 2 2 0 SLIDE Metallophos PF00149.28 CAR21698.1 - 4.1e-07 30.7 0.0 6.2e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 CAR21698.1 - 0.072 11.4 0.0 0.087 11.1 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Hpt PF01627.23 CAR21699.1 - 5.6e-12 45.8 1.0 7e-12 45.4 1.0 1.2 1 0 0 1 1 1 1 Hpt domain MgsA_C PF12002.8 CAR21700.1 - 1.1e-52 178.3 0.3 1.1e-52 178.3 0.3 1.7 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CAR21700.1 - 2.3e-23 82.3 0.2 6.4e-23 80.9 0.2 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CAR21700.1 - 1.1e-15 58.3 0.0 2.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAR21700.1 - 8e-12 45.2 0.0 3.1e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR21700.1 - 8.1e-08 32.8 0.1 5.2e-05 23.7 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 CAR21700.1 - 2.2e-07 31.0 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CAR21700.1 - 2.3e-07 30.9 0.0 4.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR21700.1 - 1.6e-05 25.2 0.3 0.00066 20.0 0.3 2.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR21700.1 - 5.8e-05 22.9 0.2 0.00026 20.7 0.1 2.1 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 CAR21700.1 - 0.00018 21.7 0.0 0.0047 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CAR21700.1 - 0.00031 20.2 0.1 0.062 12.7 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CAR21700.1 - 0.00052 19.8 0.0 0.022 14.5 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_19 PF13245.6 CAR21700.1 - 0.00067 20.0 0.6 0.17 12.2 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR21700.1 - 0.0018 18.9 0.0 0.0042 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CAR21700.1 - 0.0023 17.2 0.0 0.0043 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CAR21700.1 - 0.0033 17.2 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CAR21700.1 - 0.0035 16.9 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ResIII PF04851.15 CAR21700.1 - 0.0039 17.2 1.6 0.31 11.0 0.1 2.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CAR21700.1 - 0.0062 16.9 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase TsaE PF02367.17 CAR21700.1 - 0.0082 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CAR21700.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CAR21700.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNF220 PF15926.5 CAR21700.1 - 0.017 14.8 0.3 0.029 14.0 0.3 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 Sgf11 PF08209.11 CAR21700.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) TIP49 PF06068.13 CAR21700.1 - 0.019 14.2 0.1 0.057 12.6 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain NACHT PF05729.12 CAR21700.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CAR21700.1 - 0.024 15.2 0.1 0.056 14.0 0.1 1.9 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 CAR21700.1 - 0.028 14.5 0.1 0.074 13.1 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DNA_pol3_delta2 PF13177.6 CAR21700.1 - 0.059 13.2 0.1 12 5.7 0.1 2.7 2 1 1 3 3 3 0 DNA polymerase III, delta subunit TniB PF05621.11 CAR21700.1 - 0.063 12.7 0.0 1.2 8.5 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_33 PF13671.6 CAR21700.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CAR21700.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 CAR21700.1 - 0.18 12.1 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Hydrolase_6 PF13344.6 CAR21701.1 - 4.9e-29 100.4 0.0 1.8e-28 98.6 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR21701.1 - 2.3e-15 57.5 0.0 4.6e-15 56.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR21701.1 - 2.7e-13 49.8 0.0 4.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CAR21701.1 - 1.4e-07 31.8 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 CAR21701.1 - 0.01 15.5 0.3 0.051 13.2 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) SRP54 PF00448.22 CAR21701.1 - 0.042 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Glyco_transf_22 PF03901.17 CAR21702.1 - 5.3e-84 282.8 29.6 6.4e-84 282.6 29.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Adenylsucc_synt PF00709.21 CAR21703.1 - 6.5e-180 598.5 0.0 7.4e-180 598.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase AA_permease_2 PF13520.6 CAR21704.1 - 4.8e-71 239.8 52.9 5.8e-71 239.6 52.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR21704.1 - 2.7e-15 55.9 45.1 3.8e-15 55.5 45.1 1.1 1 0 0 1 1 1 1 Amino acid permease POP1 PF06978.11 CAR21705.1 - 3e-77 259.3 11.6 3e-77 259.3 11.6 2.0 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CAR21705.1 - 5.4e-35 119.6 0.5 3.7e-34 116.9 0.8 2.3 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 CAR21705.1 - 0.0059 16.0 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GDPD_2 PF13653.6 CAR21706.1 - 0.0039 17.6 1.0 0.0068 16.8 0.1 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ost5 PF05251.12 CAR21706.1 - 0.063 13.6 1.1 0.13 12.5 1.1 1.5 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit 5 Amidohydro_1 PF01979.20 CAR21707.1 - 2.6e-78 263.8 0.0 3e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR21707.1 - 9.1e-05 22.1 0.1 0.038 13.4 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family GAT PF03127.14 CAR21707.1 - 0.052 13.9 1.5 1.2 9.5 0.1 2.9 2 1 1 3 3 3 0 GAT domain Ssu72 PF04722.13 CAR21708.1 - 2.5e-81 271.8 0.0 2.8e-81 271.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Peptidase_C54 PF03416.19 CAR21709.1 - 7.8e-74 248.6 0.0 1.1e-73 248.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.23 CAR21710.1 - 5.3e-14 51.8 0.8 5.3e-14 51.8 0.8 1.9 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 CAR21710.1 - 0.012 15.5 0.0 0.034 14.1 0.0 1.8 1 0 0 1 1 1 0 R3H domain G-patch_2 PF12656.7 CAR21710.1 - 0.11 12.6 0.3 0.45 10.7 0.3 2.0 1 0 0 1 1 1 0 G-patch domain SID PF11778.8 CAR21711.1 - 6e-55 185.1 2.6 6e-55 185.1 2.6 2.5 2 0 0 2 2 2 1 Septation initiation Spc7 PF08317.11 CAR21711.1 - 0.00013 20.9 19.8 0.00013 20.9 19.8 5.3 2 2 2 5 5 5 4 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CAR21711.1 - 0.00057 20.0 19.6 0.00057 20.0 19.6 8.5 4 2 4 8 8 8 4 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 CAR21711.1 - 0.0024 18.1 7.3 0.0024 18.1 7.3 6.5 4 2 2 6 6 6 3 Fibrinogen alpha/beta chain family COG2 PF06148.11 CAR21711.1 - 0.017 15.2 1.7 0.017 15.2 1.7 8.0 3 2 3 7 7 7 0 COG (conserved oligomeric Golgi) complex component, COG2 Desmo_N PF06771.11 CAR21711.1 - 0.2 12.0 1.4 3.8 7.9 0.1 3.2 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DnaJ PF00226.31 CAR21712.1 - 8.9e-24 83.4 0.3 3.3e-23 81.6 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CAR21712.1 - 1.3e-08 34.9 3.9 1.3e-08 34.9 3.9 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CAR21712.1 - 1.1e-07 32.0 6.2 0.0019 18.5 2.2 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CAR21712.1 - 2.4e-06 27.7 10.0 0.0012 19.2 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR21712.1 - 6.1e-06 26.6 5.2 0.043 14.7 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CAR21712.1 - 6.9e-06 26.3 2.1 6.9e-06 26.3 2.1 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CAR21712.1 - 0.0028 17.6 6.9 0.0093 16.0 0.8 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger AKAP95 PF04988.12 CAR21712.1 - 0.033 14.4 0.3 0.033 14.4 0.3 3.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf_C2H2_ZHX PF18387.1 CAR21712.1 - 0.32 10.7 3.7 0.74 9.5 0.7 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 CAR21712.1 - 0.33 11.5 4.5 6.9 7.3 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CAR21712.1 - 0.68 10.6 4.5 12 6.6 0.0 3.0 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF1474 PF07342.11 CAR21712.1 - 4.6 7.8 8.9 0.9 10.1 0.8 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1474) GST_C PF00043.25 CAR21713.1 - 2.3e-25 88.6 0.2 1e-24 86.6 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CAR21713.1 - 5.4e-18 65.1 0.0 2.1e-17 63.2 0.0 2.1 2 0 0 2 2 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CAR21713.1 - 1.1e-09 38.6 0.0 2.9e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAR21713.1 - 1.1e-08 35.2 0.0 2.9e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR21713.1 - 2.9e-06 27.4 0.0 1.2e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR21713.1 - 0.042 13.9 0.0 0.098 12.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Roughex PF06020.11 CAR21713.1 - 0.14 11.2 3.4 0.21 10.6 3.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DUF3682 PF12446.8 CAR21713.1 - 0.39 11.2 10.8 0.64 10.5 10.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ProQ PF04352.13 CAR21713.1 - 0.57 10.1 11.4 1.6 8.6 8.9 2.2 2 0 0 2 2 2 0 ProQ/FINO family VIT1 PF01988.19 CAR21713.1 - 0.66 9.8 2.1 1.3 8.8 2.1 1.4 1 0 0 1 1 1 0 VIT family SprA-related PF12118.8 CAR21713.1 - 1.3 8.1 14.7 1.8 7.6 14.7 1.1 1 0 0 1 1 1 0 SprA-related family Androgen_recep PF02166.16 CAR21713.1 - 2 7.2 10.2 3.2 6.5 10.2 1.4 1 0 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.8 CAR21713.1 - 6.7 5.6 25.2 9.6 5.1 25.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CAR21713.1 - 7.3 6.5 18.4 9.8 6.0 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Elongin_A PF06881.11 CAR21714.1 - 2e-17 63.6 10.1 2.8e-15 56.7 10.1 2.4 1 1 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CRAL_TRIO PF00650.20 CAR21715.1 - 3.5e-41 140.6 0.0 4.9e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR21715.1 - 3e-17 62.6 1.5 5.8e-17 61.6 1.5 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EXOSC1 PF10447.9 CAR21716.1 - 4.8e-40 136.6 2.8 5.6e-40 136.4 0.5 2.0 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 S1 PF00575.23 CAR21716.1 - 0.019 15.3 1.2 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 S1 RNA binding domain Myc_N PF01056.18 CAR21716.1 - 0.04 13.8 1.3 0.052 13.4 1.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region PDZ_5 PF17817.1 CAR21717.1 - 0.036 14.3 0.1 0.15 12.4 0.1 2.0 1 0 0 1 1 1 0 PDZ domain Globin PF00042.22 CAR21718.1 - 6.8e-06 26.6 0.0 2.2e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Globin GCP_N_terminal PF17681.1 CAR21719.1 - 6.5e-43 147.5 1.3 1e-42 146.8 0.1 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CAR21719.1 - 5.8e-22 78.5 9.3 1.2e-21 77.5 9.3 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Enolase_C PF00113.22 CAR21720.1 - 2.9e-150 499.5 0.1 3.8e-150 499.1 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CAR21720.1 - 2.6e-58 195.9 0.4 4.3e-58 195.1 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CAR21720.1 - 5e-06 26.2 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CAR21720.1 - 0.0023 17.1 0.1 0.0053 16.0 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Ctr PF04145.15 CAR21721.1 - 2.2e-20 73.8 13.6 1.1e-17 65.0 13.6 2.0 1 1 0 1 1 1 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.20 CAR21721.1 - 0.01 15.4 6.9 0.011 15.3 6.9 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Tad PF13400.6 CAR21721.1 - 0.14 12.5 0.2 0.14 12.5 0.2 2.4 2 1 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like FMO-like PF00743.19 CAR21722.1 - 4.8e-42 144.1 0.0 3e-32 111.8 0.0 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CAR21722.1 - 1.4e-15 57.3 0.0 6.4e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR21722.1 - 2.6e-12 47.0 0.8 3.5e-10 40.1 0.1 3.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CAR21722.1 - 5.8e-12 45.5 0.0 5.2e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CAR21722.1 - 1e-06 28.6 0.0 0.11 12.0 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR21722.1 - 1.1e-06 28.8 0.0 3.3e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAR21722.1 - 1.6e-05 24.3 0.1 0.00014 21.2 0.1 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CAR21722.1 - 7.3e-05 22.1 0.7 0.01 15.0 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CAR21722.1 - 0.0029 16.4 0.0 0.036 12.8 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CAR21722.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase IlvN PF07991.12 CAR21722.1 - 0.043 13.4 0.1 8 6.0 0.1 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Amino_oxidase PF01593.24 CAR21722.1 - 0.046 13.0 0.1 0.63 9.2 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 CAR21722.1 - 0.062 13.4 0.0 8.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CAR21722.1 - 0.088 12.7 0.3 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CAR21722.1 - 0.088 12.0 0.0 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 CAR21722.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 CAR21722.1 - 0.14 12.2 0.0 7.2 6.6 0.0 2.8 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans PF04082.18 CAR21723.1 - 3.7e-24 85.2 0.6 7.8e-24 84.1 0.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21723.1 - 2.2e-07 30.9 11.9 4.3e-07 29.9 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2054 PF10218.9 CAR21723.1 - 0.035 14.2 3.9 0.084 13.0 3.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) Erv26 PF04148.13 CAR21724.1 - 5.8e-86 287.6 3.4 6.5e-86 287.4 3.4 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.13 CAR21724.1 - 0.032 14.5 1.6 0.065 13.5 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Cytochrom_C_asm PF01578.20 CAR21724.1 - 0.25 11.1 4.4 0.14 11.9 1.7 2.0 1 1 1 2 2 2 0 Cytochrome C assembly protein Pox_I1 PF03289.13 CAR21725.1 - 0.0029 16.8 0.1 0.0052 15.9 0.1 1.3 1 0 0 1 1 1 1 Poxvirus protein I1 RhoGAP PF00620.27 CAR21725.1 - 0.027 14.3 0.1 0.26 11.1 0.0 2.5 2 0 0 2 2 2 0 RhoGAP domain Epsilon_antitox PF08998.11 CAR21725.1 - 0.79 10.0 5.4 2.9 8.2 0.7 2.6 2 0 0 2 2 2 0 Bacterial epsilon antitoxin 6PGD PF00393.19 CAR21726.1 - 9.7e-127 422.3 0.0 1.6e-126 421.6 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CAR21726.1 - 7e-51 172.5 0.0 1e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CAR21726.1 - 0.0012 19.3 0.1 0.0023 18.5 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CAR21726.1 - 0.13 12.3 0.1 0.41 10.7 0.2 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Virulence_fact PF13769.6 CAR21727.1 - 0.091 13.0 2.9 0.28 11.4 0.1 2.7 2 1 1 3 3 3 0 Virulence factor FapA PF03961.13 CAR21727.1 - 0.59 8.7 8.8 1 7.9 8.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF489 PF04356.12 CAR21727.1 - 3.4 7.6 6.5 4.2 7.3 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) zf-CpG_bind_C PF12269.8 CAR21727.1 - 4.8 6.9 9.7 0.84 9.4 3.4 2.3 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Mito_carr PF00153.27 CAR21728.1 - 3.1e-62 206.5 0.9 2.3e-23 81.9 0.1 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.15 CAR21728.1 - 0.0082 15.8 0.2 0.2 11.3 0.1 2.4 2 0 0 2 2 2 1 Photosystem I reaction centre subunit XI VPS28 PF03997.12 CAR21729.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 VPS28 protein XPG_N PF00752.17 CAR21730.1 - 5.3e-36 123.1 0.0 1.4e-35 121.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CAR21730.1 - 6e-25 87.4 0.0 2.7e-24 85.3 0.0 2.3 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CAR21730.1 - 0.00028 21.4 0.0 0.001 19.6 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Raptor_N PF14538.6 CAR21731.1 - 2.2e-66 222.3 0.0 2.2e-66 222.3 0.0 2.6 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CAR21731.1 - 3.3e-05 23.8 0.4 0.41 11.0 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat BBS2_Mid PF14783.6 CAR21731.1 - 3.9e-05 23.6 0.0 0.0011 19.0 0.0 2.6 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 CAR21731.1 - 0.00015 22.5 4.1 3.8 8.5 0.0 6.8 6 1 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21731.1 - 0.005 17.1 0.0 11 6.4 0.0 4.7 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Cnd1 PF12717.7 CAR21731.1 - 0.012 15.6 0.6 0.13 12.3 0.1 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Exonuc_VII_L PF02601.15 CAR21731.1 - 6.3 6.3 13.8 1.7 8.1 3.8 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Elong_Iki1 PF10483.9 CAR21732.1 - 1.5e-74 251.2 0.3 1.7e-74 251.1 0.3 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DDE_3 PF13358.6 CAR21732.1 - 0.092 12.5 0.0 1.1 9.0 0.0 2.3 2 1 1 3 3 3 0 DDE superfamily endonuclease Gpi16 PF04113.14 CAR21733.1 - 5.4e-192 639.2 0.0 6.8e-192 638.8 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HEAT_2 PF13646.6 CAR21734.1 - 8e-12 45.4 2.4 2.7 8.4 0.1 8.1 7 2 3 10 10 10 4 HEAT repeats HEAT_EZ PF13513.6 CAR21734.1 - 1.2e-10 41.6 0.7 2.9 8.5 0.0 8.1 7 1 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 CAR21734.1 - 3.3e-09 36.2 12.0 0.73 10.3 0.1 8.8 10 0 0 10 10 10 2 HEAT repeat NUC173 PF08161.12 CAR21734.1 - 6.4e-07 29.2 0.3 0.014 15.1 0.0 4.0 2 1 0 3 3 3 2 NUC173 domain Cnd1 PF12717.7 CAR21734.1 - 1.4e-06 28.4 5.7 1.5 8.8 0.0 6.0 6 2 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CAR21734.1 - 1.2e-05 24.1 0.0 0.042 12.4 0.0 4.4 4 1 1 5 5 5 1 Adaptin N terminal region DUF3385 PF11865.8 CAR21734.1 - 0.00046 20.1 4.6 0.39 10.6 0.1 5.3 5 2 0 6 6 6 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 CAR21734.1 - 0.00098 18.3 0.0 6.4 5.8 0.0 4.3 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal IFRD PF05004.13 CAR21734.1 - 0.0018 17.5 0.1 3.4 6.7 0.0 3.3 2 2 0 2 2 2 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 CAR21734.1 - 0.002 18.7 0.5 12 6.6 0.0 4.6 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CAR21735.1 - 4.9e-92 309.2 0.6 5.9e-92 308.9 0.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR21735.1 - 7.4e-16 58.6 4.1 1.2e-08 35.2 0.0 3.8 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAR21735.1 - 7.8e-10 38.2 6.8 0.0016 18.5 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 CAR21735.1 - 1.2e-08 35.3 9.4 0.0024 18.2 0.2 5.8 4 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 CAR21735.1 - 0.00034 21.1 1.5 4.3 8.0 0.0 4.4 5 0 0 5 5 5 2 HEAT-like repeat Cohesin_HEAT PF12765.7 CAR21735.1 - 0.0034 17.6 10.7 0.24 11.7 0.1 4.2 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion UNC45-central PF11701.8 CAR21735.1 - 0.045 13.7 0.1 1.3 8.9 0.0 3.0 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 CAR21735.1 - 0.11 12.1 0.0 6.5 6.3 0.0 2.6 1 1 1 2 2 2 0 CLASP N terminal SulA PF03846.14 CAR21735.1 - 0.25 11.3 0.8 21 5.1 0.2 2.9 3 0 0 3 3 3 0 Cell division inhibitor SulA Aminotran_4 PF01063.19 CAR21736.1 - 5e-15 56.0 0.0 7.8e-15 55.3 0.0 1.3 1 1 0 1 1 1 1 Amino-transferase class IV DUF4446 PF14584.6 CAR21736.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) T7SS_ESX_EspC PF10824.8 CAR21736.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm YozD PF14162.6 CAR21736.1 - 0.13 12.5 0.4 10 6.5 0.0 3.3 3 1 1 4 4 4 0 YozD-like protein Kdo PF06293.14 CAR21737.1 - 1.6e-07 30.9 0.0 2.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR21737.1 - 0.00035 20.6 0.0 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAR21737.1 - 0.00074 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 CAR21737.1 - 0.0054 16.1 0.0 0.0075 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_1g PF09334.11 CAR21738.1 - 1.9e-157 524.0 0.3 1.9e-157 524.0 0.3 1.7 3 0 0 3 3 3 1 tRNA synthetases class I (M) MetRS-N PF09635.10 CAR21738.1 - 2.2e-46 157.4 2.4 2.2e-46 157.4 2.4 2.0 2 0 0 2 2 2 1 MetRS-N binding domain tRNA-synt_1 PF00133.22 CAR21738.1 - 3.3e-10 38.8 0.6 0.00051 18.4 0.4 2.4 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CAR21738.1 - 0.0094 15.3 0.0 0.039 13.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Sigma54_CBD PF04963.13 CAR21738.1 - 0.043 13.7 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain DEAD PF00270.29 CAR21739.1 - 1.3e-46 158.5 1.2 2e-46 158.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR21739.1 - 1e-24 87.0 0.0 7.6e-24 84.2 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR21739.1 - 5.9e-19 68.0 0.4 1.1e-18 67.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAR21739.1 - 4.2e-06 26.9 0.1 8.2e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR21739.1 - 1.7e-05 24.2 0.0 5.9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 CAR21739.1 - 0.0022 17.4 0.0 0.0073 15.6 0.0 1.6 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_30 PF13604.6 CAR21739.1 - 0.056 13.2 0.1 0.64 9.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CAR21739.1 - 0.18 12.1 0.5 0.69 10.2 0.5 2.1 1 1 0 1 1 1 0 AAA domain PhoD PF09423.10 CAR21740.1 - 3e-05 23.2 0.0 0.00016 20.8 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase Pkinase PF00069.25 CAR21741.1 - 1.2e-48 165.8 0.1 6.4e-47 160.1 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21741.1 - 7.4e-23 81.2 0.2 3.5e-22 78.9 0.1 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR21741.1 - 0.00068 18.5 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAR21741.1 - 0.012 15.0 0.2 0.47 9.7 0.0 2.5 3 0 0 3 3 3 0 Kinase-like GTP_cyclohydroI PF01227.22 CAR21742.1 - 2.5e-77 258.3 1.2 3e-77 258.1 1.2 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CAR21742.1 - 1.6e-05 24.9 0.0 6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein Endopep_inhib PF16800.5 CAR21742.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor OmpH PF03938.14 CAR21742.1 - 0.13 12.6 0.5 1.1 9.6 0.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DnaJ_CXXCXGXG PF00684.19 CAR21743.1 - 1.9e-05 24.9 6.8 0.025 14.9 0.6 2.3 2 0 0 2 2 2 2 DnaJ central domain HypA PF01155.19 CAR21743.1 - 0.22 11.6 2.2 2.8 8.0 0.2 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Got1 PF04178.12 CAR21744.1 - 1.8e-13 50.9 16.9 5.9e-13 49.2 16.4 1.8 1 1 1 2 2 2 1 Got1/Sft2-like family DUF3784 PF12650.7 CAR21744.1 - 0.074 13.2 8.8 0.3 11.3 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF1129 PF06570.11 CAR21744.1 - 1.2 8.6 5.4 1.6 8.2 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) SdpI PF13630.6 CAR21744.1 - 1.3 9.2 9.1 5.8 7.1 0.9 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF373 PF04123.13 CAR21744.1 - 4 6.8 5.8 7.7 5.9 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) AAA PF00004.29 CAR21745.1 - 4.3e-47 159.9 0.0 2.4e-42 144.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR21745.1 - 3e-10 39.8 0.0 8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CAR21745.1 - 2e-06 28.3 0.4 0.00017 22.0 0.1 3.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CAR21745.1 - 7.9e-06 26.1 0.0 2.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CAR21745.1 - 3.4e-05 23.6 0.0 9.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 CAR21745.1 - 6.7e-05 23.0 0.0 0.42 10.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 CAR21745.1 - 9.8e-05 22.4 0.0 0.00037 20.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 CAR21745.1 - 0.00073 19.6 0.0 0.0024 17.9 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Bromodomain PF00439.25 CAR21745.1 - 0.0014 18.6 0.0 0.005 16.9 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_7 PF12775.7 CAR21745.1 - 0.0016 18.0 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 CAR21745.1 - 0.0065 16.8 0.4 0.13 12.5 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CAR21745.1 - 0.0072 16.4 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 CAR21745.1 - 0.0098 15.6 0.0 0.52 10.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain TIP49 PF06068.13 CAR21745.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 CAR21745.1 - 0.016 15.5 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CAR21745.1 - 0.025 14.8 0.0 0.059 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CAR21745.1 - 0.036 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CAR21745.1 - 0.039 14.5 0.0 0.039 14.5 0.0 2.6 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.17 CAR21745.1 - 0.04 13.0 0.1 0.73 8.9 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 CAR21745.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CAR21745.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CAR21745.1 - 0.076 13.6 0.0 0.37 11.3 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CAR21745.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CAR21745.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CAR21745.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 CAR21745.1 - 0.46 10.2 0.0 0.46 10.2 0.0 3.5 3 1 0 3 3 1 0 AAA domain Amidase PF01425.21 CAR21746.1 - 1.4e-118 396.7 0.0 1.7e-118 396.4 0.0 1.0 1 0 0 1 1 1 1 Amidase Dynamitin PF04912.14 CAR21747.1 - 1.5e-27 97.0 27.2 2.1e-25 89.9 27.2 2.1 1 1 0 1 1 1 1 Dynamitin BST2 PF16716.5 CAR21747.1 - 0.074 13.6 1.1 0.074 13.6 1.1 3.5 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 NPV_P10 PF05531.12 CAR21747.1 - 0.21 12.1 12.6 5.7 7.5 1.1 4.9 2 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein DHC PF09626.10 CAR21747.1 - 0.42 11.5 4.4 6.9 7.6 0.5 2.7 2 1 1 3 3 3 0 Dihaem cytochrome c Atg14 PF10186.9 CAR21747.1 - 1.5 7.8 21.9 0.26 10.3 16.6 2.0 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rx_N PF18052.1 CAR21747.1 - 2.1 8.7 16.0 0.18 12.1 1.6 4.2 3 1 1 4 4 4 0 Rx N-terminal domain Fib_alpha PF08702.10 CAR21747.1 - 2.4 8.3 25.2 0.066 13.4 4.7 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family FeoB_Cyto PF17910.1 CAR21747.1 - 5.7 7.6 11.5 0.58 10.7 1.0 3.1 3 1 0 3 3 3 0 FeoB cytosolic helical domain Gal4_dimer PF03902.13 CAR21747.1 - 7.5 6.8 7.8 12 6.2 0.0 3.7 4 0 0 4 4 4 0 Gal4-like dimerisation domain Sec63 PF02889.16 CAR21748.1 - 3.1e-121 403.4 0.7 2.7e-79 266.0 0.2 3.1 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 CAR21748.1 - 2.9e-49 167.2 0.8 1.3e-25 90.1 0.6 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 CAR21748.1 - 9.5e-31 107.1 0.0 3.9e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAR21748.1 - 5.8e-20 71.7 0.1 1.1e-08 35.3 0.1 3.8 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA PF00004.29 CAR21748.1 - 1.1e-06 29.1 3.2 0.067 13.6 0.0 5.0 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR21748.1 - 4.5e-06 27.0 4.0 0.089 13.1 0.3 4.4 3 2 0 3 3 2 2 AAA domain AAA_19 PF13245.6 CAR21748.1 - 0.00016 22.0 0.5 0.034 14.5 0.3 2.8 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CAR21748.1 - 0.00021 20.8 0.0 0.046 13.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Helicase_PWI PF18149.1 CAR21748.1 - 0.00055 20.1 1.2 0.0021 18.2 1.2 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain IstB_IS21 PF01695.17 CAR21748.1 - 0.012 15.4 0.5 2.1 8.0 0.0 3.8 5 0 0 5 5 5 0 IstB-like ATP binding protein T2SSE PF00437.20 CAR21748.1 - 0.019 14.0 0.0 4.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 CAR21748.1 - 0.1 12.1 0.1 8.6 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_23 PF13476.6 CAR21748.1 - 0.54 10.7 6.8 1e+02 3.3 6.3 3.5 3 0 0 3 3 3 0 AAA domain Efg1 PF10153.9 CAR21749.1 - 1.2e-25 90.1 13.5 1.2e-25 90.1 13.5 2.5 2 1 0 2 2 2 1 rRNA-processing protein Efg1 EMA PF02488.15 CAR21749.1 - 0.0072 16.0 0.7 0.01 15.5 0.7 1.2 1 0 0 1 1 1 1 Merozoite Antigen AbbA_antirepres PF14156.6 CAR21749.1 - 0.16 11.9 1.3 0.27 11.2 0.6 1.7 2 0 0 2 2 2 0 Antirepressor AbbA DUF2406 PF10295.9 CAR21750.1 - 1.7e-27 95.9 0.5 3.2e-27 95.0 0.5 1.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Fungal_trans PF04082.18 CAR21751.1 - 3.1e-16 59.2 0.3 5.9e-16 58.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21751.1 - 5.4e-09 36.0 13.7 1.1e-08 35.1 13.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 CAR21752.1 - 3.8e-62 209.6 15.5 5.5e-62 209.0 15.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Aminotran_1_2 PF00155.21 CAR21753.1 - 4.9e-61 206.9 0.0 5.9e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CAR21753.1 - 0.00057 18.5 0.0 0.0011 17.6 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Mut7-C PF01927.16 CAR21753.1 - 0.12 12.5 0.2 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Mut7-C RNAse domain Peptidase_S10 PF00450.22 CAR21754.1 - 9.6e-130 433.7 1.1 1.1e-129 433.5 1.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 CAR21754.1 - 2.8e-14 53.7 4.5 3.7e-13 50.1 4.5 2.3 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide DUF3591 PF12157.8 CAR21756.1 - 1e-176 588.0 0.2 1.9e-176 587.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CAR21756.1 - 5.1e-06 26.2 1.2 1.1e-05 25.2 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle SAP30_Sin3_bdg PF13867.6 CAR21756.1 - 0.078 13.3 0.1 0.26 11.7 0.1 1.9 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Rtt102p PF09510.10 CAR21757.1 - 1.2e-45 154.9 0.7 1.9e-45 154.3 0.7 1.3 1 0 0 1 1 1 1 Rtt102p-like transcription regulator protein RNase_T PF00929.24 CAR21758.1 - 1.2e-07 32.4 0.0 3.6e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Exonuclease DUF1381 PF07129.11 CAR21758.1 - 0.085 12.7 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) GATase_6 PF13522.6 CAR21760.1 - 8.6e-13 48.6 0.0 2.4e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CAR21760.1 - 1.6e-09 37.7 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CAR21760.1 - 8.3e-09 35.2 0.1 1.5e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CAR21760.1 - 0.00031 19.8 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ABC_membrane PF00664.23 CAR21761.1 - 8.8e-44 150.2 16.9 1.1e-43 149.9 16.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CAR21761.1 - 2e-35 122.3 0.0 4.4e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CAR21761.1 - 1.1e-09 38.1 0.0 4e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR21761.1 - 0.00053 19.7 0.2 0.0013 18.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CAR21761.1 - 0.0012 18.8 0.2 0.016 15.0 0.1 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CAR21761.1 - 0.0012 19.3 0.0 0.0027 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR21761.1 - 0.0068 16.7 0.0 0.026 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.12 CAR21761.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_15 PF13175.6 CAR21761.1 - 0.026 14.3 0.1 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 CAR21761.1 - 0.035 13.8 0.0 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 CAR21761.1 - 0.043 12.6 0.1 0.67 8.7 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_23 PF13476.6 CAR21761.1 - 0.071 13.6 0.2 0.071 13.6 0.2 2.8 3 0 0 3 3 3 0 AAA domain DUF3987 PF13148.6 CAR21761.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 CAR21761.1 - 0.096 12.4 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAR21761.1 - 0.15 11.3 0.0 0.52 9.5 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin DUF2878 PF11086.8 CAR21761.1 - 0.64 10.2 3.5 0.41 10.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2878) Proteasome PF00227.26 CAR21762.1 - 8.4e-46 155.9 0.0 1e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR21762.1 - 2.1e-12 46.5 0.3 1.3e-11 43.9 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF3336 PF11815.8 CAR21763.1 - 1.9e-27 95.7 0.0 3.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CAR21763.1 - 7.7e-07 29.5 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase RAC_head PF16717.5 CAR21765.1 - 2.3e-19 70.2 6.2 2.3e-19 70.2 6.2 3.7 3 2 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 CAR21765.1 - 3.1e-17 62.5 0.5 1.1e-16 60.6 0.5 2.1 1 0 0 1 1 1 1 DnaJ domain SURF4 PF02077.15 CAR21766.1 - 3.2e-92 308.9 11.4 4e-92 308.6 11.4 1.1 1 0 0 1 1 1 1 SURF4 family MerC PF03203.14 CAR21766.1 - 8.2 6.9 16.5 0.93 10.0 3.1 2.4 1 1 1 2 2 2 0 MerC mercury resistance protein IPP-2 PF04979.14 CAR21767.1 - 5.7e-23 82.1 7.9 5.7e-23 82.1 7.9 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Methyltrn_RNA_3 PF02598.17 CAR21768.1 - 2.3e-75 253.8 0.0 3e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase Glyco_hydro_17 PF00332.18 CAR21769.1 - 5.7e-87 292.2 1.7 6.5e-87 292.1 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 eRF1_2 PF03464.15 CAR21769.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 eRF1 domain 2 eIF-3c_N PF05470.12 CAR21770.1 - 1e-156 522.8 11.8 1.2e-120 403.7 0.4 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CAR21770.1 - 2.6e-16 60.0 0.8 2.8e-15 56.7 0.1 3.1 3 1 0 3 3 3 1 PCI domain DUF2034 PF10356.9 CAR21770.1 - 0.0051 16.3 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Sigma70_r4 PF04545.16 CAR21770.1 - 0.032 13.7 0.4 1.4 8.5 0.0 3.3 3 0 0 3 3 3 0 Sigma-70, region 4 HTH_Tnp_ISL3 PF13542.6 CAR21770.1 - 0.1 12.0 0.1 0.86 9.1 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDRGK PF09756.9 CAR21770.1 - 0.58 9.7 5.7 2.1 7.9 0.1 3.4 2 1 1 3 3 3 0 DDRGK domain AAA_11 PF13086.6 CAR21770.1 - 1.2 8.8 7.7 5.3 6.7 0.0 3.4 2 1 1 3 3 3 0 AAA domain ABC_membrane PF00664.23 CAR21771.1 - 1.2e-72 244.8 41.5 7.1e-45 153.8 15.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAR21771.1 - 4e-45 153.7 1.0 1.8e-27 96.5 0.0 3.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAR21771.1 - 3.2e-10 40.3 0.1 0.017 15.0 0.0 4.0 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR21771.1 - 2.8e-08 33.5 5.8 0.015 14.7 0.5 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR21771.1 - 1.3e-06 28.0 1.2 0.035 13.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CAR21771.1 - 2.9e-06 27.3 2.1 0.071 12.8 0.0 3.5 3 1 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 CAR21771.1 - 4.2e-05 23.5 0.7 0.069 13.1 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR21771.1 - 0.00013 22.0 0.6 0.15 12.1 0.0 3.3 3 0 0 3 3 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 CAR21771.1 - 0.00024 20.3 0.6 0.022 13.8 0.1 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 CAR21771.1 - 0.00032 21.3 0.1 0.25 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CAR21771.1 - 0.0059 16.2 0.3 0.75 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAR21771.1 - 0.012 14.9 0.1 2.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 CAR21771.1 - 0.013 15.0 0.5 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 CAR21771.1 - 0.018 15.4 0.0 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain MeaB PF03308.16 CAR21771.1 - 0.019 13.9 1.2 0.44 9.5 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CAR21771.1 - 0.029 14.7 0.2 11 6.5 0.0 3.2 2 0 0 2 2 2 0 RNA helicase Vps51 PF08700.11 CAR21771.1 - 0.035 14.2 0.0 0.096 12.8 0.0 1.7 1 0 0 1 1 1 0 Vps51/Vps67 AAA_23 PF13476.6 CAR21771.1 - 0.038 14.5 16.2 0.096 13.2 0.1 3.5 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CAR21771.1 - 0.043 13.6 1.0 7.4 6.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 CAR21771.1 - 0.069 13.2 0.2 0.24 11.4 0.2 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 CAR21771.1 - 0.092 12.5 3.0 1.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CAR21771.1 - 0.1 12.9 6.5 4.1 7.7 1.1 3.4 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CAR21771.1 - 0.11 12.2 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 CAR21771.1 - 0.11 12.2 10.3 0.65 9.7 0.2 3.5 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 CAR21771.1 - 0.13 12.2 3.0 6.4 6.7 0.1 3.2 3 0 0 3 3 3 0 NTPase Fungal_trans PF04082.18 CAR21772.1 - 3.2e-16 59.2 0.1 6e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3839 PF12943.7 CAR21772.1 - 0.073 12.5 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3839) ABC_tran_CTD PF16326.5 CAR21772.1 - 0.094 13.0 0.9 0.37 11.1 0.9 2.0 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF1319 PF07028.11 CAR21772.1 - 0.2 11.9 1.3 1.4 9.2 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) Importin_rep_6 PF18829.1 CAR21773.1 - 3.1e-50 168.8 1.9 3.1e-50 168.8 1.9 4.1 4 0 0 4 4 4 1 Importin repeat 6 Importin_rep_4 PF18808.1 CAR21773.1 - 1.3e-33 115.1 0.5 1.3e-33 115.1 0.5 3.5 4 0 0 4 4 4 1 Importin repeat Importin_rep_5 PF18816.1 CAR21773.1 - 4.2e-25 87.8 3.1 1.1e-24 86.5 0.8 2.8 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 CAR21773.1 - 1.3e-21 76.7 5.7 3e-12 46.8 0.0 7.9 6 1 2 8 8 7 3 HEAT-like repeat HEAT_2 PF13646.6 CAR21773.1 - 8e-14 51.8 0.0 2.2e-06 28.0 0.0 6.6 4 2 3 7 7 7 3 HEAT repeats HEAT PF02985.22 CAR21773.1 - 1.7e-13 49.5 0.7 0.0073 16.5 0.0 8.7 10 0 0 10 10 8 3 HEAT repeat RIX1 PF08167.12 CAR21773.1 - 9e-13 48.4 2.5 0.00027 20.7 0.2 5.0 5 1 0 6 6 6 2 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 CAR21773.1 - 1.2e-11 43.9 0.4 0.0061 15.2 0.1 4.6 3 2 0 4 4 4 4 Adaptin N terminal region Arm PF00514.23 CAR21773.1 - 9.1e-07 28.7 4.3 1.1 9.4 0.0 5.5 5 0 0 5 5 4 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CAR21773.1 - 1.7e-06 28.5 0.0 0.084 13.5 0.0 5.8 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 CAR21773.1 - 4.1e-05 22.9 10.8 0.02 14.0 3.3 3.8 3 1 1 4 4 4 3 RNAPII transcription regulator C-terminal IFRD PF05004.13 CAR21773.1 - 4.9e-05 22.6 6.4 0.022 13.9 0.2 3.4 3 1 0 3 3 3 2 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 CAR21773.1 - 7.1e-05 22.8 3.4 0.2 11.5 0.2 5.3 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 CAR21773.1 - 0.0003 20.4 0.1 0.046 13.3 0.0 3.4 3 0 0 3 3 3 1 CLASP N terminal DNA_alkylation PF08713.11 CAR21773.1 - 0.0072 16.1 0.0 0.054 13.2 0.0 2.4 2 0 0 2 2 2 1 DNA alkylation repair enzyme ParcG PF10274.9 CAR21773.1 - 0.034 14.3 3.4 0.44 10.6 0.1 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein PBP1_TM PF14812.6 CAR21773.1 - 0.035 14.5 0.7 0.035 14.5 0.7 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RTP1_C1 PF10363.9 CAR21773.1 - 0.089 13.0 0.2 47 4.2 0.1 4.6 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Turandot PF07240.11 CAR21773.1 - 0.42 10.6 1.8 2.1 8.4 0.7 2.8 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot G-patch PF01585.23 CAR21774.1 - 8.1e-11 41.6 0.1 1.8e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CAR21774.1 - 0.00081 19.4 0.2 0.00081 19.4 0.2 3.9 2 1 0 2 2 2 1 G-patch domain Glyco_hydro_72 PF03198.14 CAR21775.1 - 2.1e-142 474.0 8.7 2.8e-142 473.6 8.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CAR21775.1 - 3e-25 88.7 4.7 8.9e-25 87.2 4.7 1.9 1 0 0 1 1 1 1 X8 domain GEN1_C PF18380.1 CAR21775.1 - 0.18 12.7 0.0 0.36 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Period_C PF12114.8 CAR21775.1 - 0.41 10.2 21.3 0.96 9.0 21.3 1.6 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Apt1 PF10351.9 CAR21775.1 - 1.3 7.8 7.9 2 7.2 7.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1644 PF07800.12 CAR21775.1 - 4.6 7.3 9.8 4 7.5 0.0 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF1644) Glyco_hydro_72 PF03198.14 CAR21776.1 - 4.7e-144 479.4 12.4 6.7e-144 478.9 12.4 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CAR21776.1 - 9.3e-28 96.7 6.4 3.3e-27 95.0 6.4 2.1 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.17 CAR21776.1 - 0.0015 17.7 2.3 0.0043 16.2 2.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glucan_synthase PF02364.15 CAR21777.1 - 0 1374.6 0.3 0 1374.6 0.3 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CAR21777.1 - 3.4e-40 137.3 1.2 2.3e-39 134.7 1.2 2.4 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3817 PF12823.7 CAR21777.1 - 0.006 17.4 6.3 0.006 17.4 6.3 3.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3817) Apt1 PF10351.9 CAR21778.1 - 0.84 8.4 11.7 1 8.1 11.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CAR21778.1 - 1.2 7.5 16.0 1.5 7.3 16.0 1.2 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 CAR21778.1 - 1.7 7.8 21.1 2.4 7.3 21.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 CAR21778.1 - 3.8 7.3 13.3 4.9 7.0 13.3 1.1 1 0 0 1 1 1 0 SPX domain MA3 PF02847.17 CAR21779.1 - 7.3e-21 74.3 0.0 2.6e-20 72.5 0.0 2.0 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CAR21779.1 - 7.8e-06 25.7 3.3 1.9e-05 24.4 2.5 1.9 2 0 0 2 2 2 1 MIF4G domain CTP_transf_like PF01467.26 CAR21780.1 - 9e-10 38.9 0.0 2e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase-like USP7_C2 PF14533.6 CAR21781.1 - 8.4e-55 185.7 5.1 7.4e-54 182.6 2.2 3.3 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 CAR21781.1 - 6.4e-45 153.6 0.6 1.2e-44 152.8 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CAR21781.1 - 1.5e-35 122.6 1.7 9e-34 116.8 0.1 2.6 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CAR21781.1 - 2.2e-22 80.1 0.0 1.1e-21 77.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNA12 PF10443.9 CAR21782.1 - 1.1e-168 561.6 0.4 4.3e-168 559.6 0.1 2.0 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 CAR21782.1 - 9.5e-06 25.3 0.0 3.1e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 CAR21782.1 - 0.001 19.0 0.6 0.019 14.9 0.0 3.1 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CAR21782.1 - 0.014 15.4 0.2 0.13 12.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain Hydantoinase_B PF02538.14 CAR21783.1 - 5.3e-208 691.6 0.1 6.9e-208 691.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CAR21783.1 - 6.2e-101 337.5 0.2 1.4e-100 336.4 0.2 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CAR21783.1 - 1.4e-53 181.3 0.1 9e-52 175.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 CAR21784.1 - 9.8e-41 139.8 25.0 1.2e-40 139.5 25.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 CAR21785.1 - 5.6e-12 45.2 2.1 1.1e-11 44.3 2.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21785.1 - 0.00083 19.4 12.9 0.0016 18.5 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.12 CAR21786.1 - 5.3e-56 188.5 0.0 6.7e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.16 CAR21787.1 - 5.1e-39 134.2 49.3 1.2e-30 106.7 26.9 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR21787.1 - 5.4e-13 48.2 19.6 1.8e-12 46.5 19.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ferritin_2 PF13668.6 CAR21788.1 - 2.4e-41 141.1 1.6 3.4e-41 140.6 1.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain PHO4 PF01384.20 CAR21789.1 - 2.9e-117 391.5 15.7 3.5e-117 391.2 15.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tautomerase PF01361.21 CAR21789.1 - 0.14 12.1 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DUP PF00674.18 CAR21790.1 - 7.6e-19 67.8 0.1 1.4e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 DUP family DUP PF00674.18 CAR21791.1 - 3.1e-16 59.4 0.2 8e-16 58.1 0.1 1.6 1 1 1 2 2 2 1 DUP family DUF4111 PF13427.6 CAR21791.1 - 0.031 14.4 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) DUP PF00674.18 CAR21792.1 - 1.6e-12 47.5 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 DUP family DUP PF00674.18 CAR21793.1 - 3.2e-12 46.5 1.2 5.1e-12 45.8 0.5 1.6 2 0 0 2 2 2 1 DUP family Sir1 PF11603.8 CAR21794.1 - 4.4e-31 107.9 0.9 6.2e-30 104.2 0.2 2.8 2 0 0 2 2 2 1 Regulatory protein Sir1 DEAD PF00270.29 CAR21794.1 - 2.5e-10 40.4 0.0 6.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR21794.1 - 9.1e-08 32.4 0.0 2.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR21794.1 - 0.00088 19.3 0.0 0.0029 17.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR21794.1 - 0.023 15.0 0.1 0.65 10.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain Bcr-Abl_Oligo PF09036.10 CAR21794.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain NUP PF06516.11 CAR21795.1 - 5.6e-67 226.2 0.0 6.7e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) MFS_1 PF07690.16 CAR21796.1 - 2.1e-36 125.6 26.2 2.1e-36 125.6 26.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CRPA PF05745.11 CAR21796.1 - 0.09 12.8 1.1 0.42 10.6 0.3 2.5 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) OppC_N PF12911.7 CAR21796.1 - 0.8 9.7 3.3 2.6 8.1 0.2 3.2 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Sir1 PF11603.8 CAR21797.1 - 3e-30 105.2 0.1 1e-29 103.5 0.1 2.0 1 0 0 1 1 1 1 Regulatory protein Sir1 Helicase_C PF00271.31 CAR21797.1 - 2.1e-12 47.3 0.0 6.3e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR21797.1 - 8.3e-07 28.9 0.0 3.9e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase MFS_1 PF07690.16 CAR21798.1 - 1.2e-09 37.6 54.3 2.2e-07 30.1 53.2 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR21798.1 - 1.1e-05 24.5 12.0 1.1e-05 24.5 12.0 3.7 4 1 1 5 5 5 1 Sugar (and other) transporter Amidase PF01425.21 CAR21799.1 - 1.3e-77 261.7 0.0 5.9e-76 256.2 0.0 2.1 2 0 0 2 2 2 2 Amidase Arylsulfotran_2 PF14269.6 CAR21800.1 - 1.8e-70 237.7 3.8 2.4e-70 237.3 3.8 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CAR21800.1 - 6.7e-17 61.4 2.6 2.2e-16 59.8 2.6 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Acetyltransf_3 PF13302.7 CAR21801.1 - 6.7e-12 46.3 0.0 9.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR21801.1 - 9.2e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUP PF00674.18 CAR21802.1 - 8.9e-19 67.5 0.5 1.5e-18 66.8 0.1 1.6 2 0 0 2 2 2 1 DUP family FeoB_C PF07664.12 CAR21802.1 - 0.23 11.2 1.4 0.37 10.5 1.4 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus PhyH PF05721.13 CAR21803.1 - 4e-19 69.7 0.0 5.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 CAR21804.1 - 4.9e-15 55.3 28.3 4.9e-15 55.3 28.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4328 PF14219.6 CAR21804.1 - 2.2 7.8 9.1 4.2 6.9 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) MFS_1 PF07690.16 CAR21805.1 - 8.4e-21 74.3 10.9 1.3e-20 73.7 10.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF997 PF06196.12 CAR21805.1 - 0.074 13.1 0.5 0.074 13.1 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Zip PF02535.22 CAR21806.1 - 1.3e-58 198.8 1.0 1.6e-58 198.6 1.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter His_Phos_2 PF00328.22 CAR21807.1 - 9.1e-52 176.7 0.0 1.2e-51 176.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HRXXH PF13933.6 CAR21808.1 - 4e-88 295.1 0.3 4.7e-88 294.9 0.3 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 CAR21808.1 - 5.7e-07 30.2 0.8 1.3e-06 29.0 0.1 2.0 2 1 0 2 2 2 1 Lysine-specific metallo-endopeptidase Flocculin PF00624.18 CAR21809.1 - 0 1611.4 1414.4 3e-15 56.2 28.4 45.4 43 3 2 45 45 45 37 Flocculin repeat Candida_ALS_N PF11766.8 CAR21809.1 - 1.2e-53 181.9 10.4 1.2e-53 181.9 10.4 8.6 12 4 6 18 18 18 1 Cell-wall agglutinin N-terminal ligand-sugar binding Sugar_tr PF00083.24 CAR21810.1 - 5.8e-168 559.4 32.7 6.7e-168 559.2 32.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR21810.1 - 6.2e-30 104.3 32.5 3.2e-28 98.7 19.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LMF1 PF06762.14 CAR21810.1 - 0.17 10.9 3.6 0.29 10.2 3.6 1.3 1 0 0 1 1 1 0 Lipase maturation factor Pan3_PK PF18101.1 CAR21811.1 - 3.8e-52 175.9 0.1 7.7e-52 174.9 0.0 1.5 2 0 0 2 2 2 1 Pan3 Pseudokinase domain adh_short PF00106.25 CAR21812.1 - 3.6e-44 150.6 0.8 1.7e-33 115.7 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAR21812.1 - 1.5e-25 90.2 0.8 6.5e-23 81.5 0.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR21812.1 - 4e-09 36.6 1.8 7.9e-09 35.7 0.4 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 CAR21812.1 - 4.8e-06 26.2 0.1 8e-06 25.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CAR21812.1 - 0.0015 18.4 0.2 0.002 18.0 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CAR21812.1 - 0.0042 16.1 0.1 0.0063 15.6 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Mannitol_dh PF01232.23 CAR21812.1 - 0.0081 16.3 0.0 0.045 13.9 0.0 2.0 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain BBS2_N PF14781.6 CAR21812.1 - 0.028 14.3 0.1 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DUF2400 PF09674.10 CAR21812.1 - 0.11 12.5 0.0 3.3 7.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) ADK PF00406.22 CAR21813.1 - 8.7e-47 159.0 0.0 1.1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAR21813.1 - 2.4e-35 121.9 0.0 3.4e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR21813.1 - 7.4e-09 36.2 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CAR21813.1 - 2.3e-06 27.4 0.1 0.01 15.5 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 CAR21813.1 - 9.3e-05 22.6 0.0 0.00028 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CAR21813.1 - 0.0015 17.8 0.0 0.0024 17.2 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin SRP54 PF00448.22 CAR21813.1 - 0.012 15.2 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 CAR21813.1 - 0.017 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 TPR_2 PF07719.17 CAR21815.1 - 1.5e-35 118.4 9.3 0.0023 17.9 0.0 10.9 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 CAR21815.1 - 6.6e-34 114.4 12.0 9.6e-05 22.0 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR21815.1 - 1.6e-31 108.4 18.4 4.2e-26 91.0 0.1 5.8 5 1 1 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAR21815.1 - 3.6e-25 86.0 11.2 0.00015 21.7 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 CAR21815.1 - 4.6e-20 71.7 10.1 8.9e-07 29.1 0.1 9.4 7 2 3 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 CAR21815.1 - 9.8e-20 70.8 5.9 0.0046 17.4 0.2 7.6 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAR21815.1 - 3.1e-17 61.8 0.0 0.033 15.0 0.1 8.4 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAR21815.1 - 1.7e-15 55.8 11.1 0.00016 21.5 0.0 7.5 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAR21815.1 - 1.4e-14 54.5 0.7 0.00094 19.8 0.0 6.5 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CAR21815.1 - 2e-13 49.7 3.2 0.79 10.2 0.0 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR21815.1 - 7.6e-13 47.9 4.0 0.00039 20.0 0.0 7.6 6 2 2 8 8 8 2 TPR repeat TPR_6 PF13174.6 CAR21815.1 - 7.7e-10 38.8 8.5 4.2 8.2 0.0 8.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAR21815.1 - 1.1e-09 37.9 5.9 0.069 13.0 0.0 7.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAR21815.1 - 4.4e-08 33.1 0.0 0.00018 21.6 0.2 4.6 6 1 1 7 7 6 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CAR21815.1 - 8.7e-06 25.7 4.3 0.01 15.9 0.0 4.3 3 1 1 4 4 4 1 Putative TPR-like repeat TPR_MalT PF17874.1 CAR21815.1 - 0.00029 20.3 0.1 0.03 13.7 0.1 3.8 3 1 0 3 3 3 1 MalT-like TPR region Coatomer_E PF04733.14 CAR21815.1 - 0.00032 20.2 1.2 3.3 7.0 0.1 5.3 5 2 2 7 7 7 1 Coatomer epsilon subunit TPR_20 PF14561.6 CAR21815.1 - 0.00041 20.6 0.1 0.58 10.5 0.1 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 CAR21815.1 - 0.00046 20.1 1.1 18 5.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 CAR21815.1 - 0.0032 17.5 0.1 1 9.5 0.0 3.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 CAR21815.1 - 6.7 6.9 16.6 16 5.7 0.1 6.6 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat AlaDh_PNT_N PF05222.15 CAR21816.1 - 3.9e-28 98.4 0.0 5.9e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CAR21816.1 - 0.021 14.1 0.0 0.12 11.6 0.0 2.0 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 CAR21817.1 - 2.3e-21 75.7 7.9 3.8e-06 27.5 0.3 4.9 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21817.1 - 6.1e-08 32.9 1.3 0.96 9.8 0.0 4.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CAR21817.1 - 9.2e-06 24.7 4.1 0.82 8.3 0.1 4.3 3 1 2 5 5 5 3 Nup133 N terminal like Nup160 PF11715.8 CAR21817.1 - 0.00032 19.5 0.3 0.73 8.4 0.0 2.8 3 1 0 3 3 3 2 Nucleoporin Nup120/160 EF-hand_11 PF08976.11 CAR21817.1 - 0.0037 18.1 0.0 0.0097 16.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain BBS2_Mid PF14783.6 CAR21817.1 - 0.0046 17.0 2.0 5.1 7.2 0.1 4.0 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Ank_4 PF13637.6 CAR21818.1 - 1.3e-10 41.6 0.2 0.00062 20.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR21818.1 - 3.5e-09 37.1 0.2 1e-08 35.7 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CAR21818.1 - 1.3e-08 34.9 1.1 0.0029 18.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CAR21818.1 - 2e-08 33.8 0.7 0.015 15.8 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat TIG PF01833.24 CAR21818.1 - 2.1e-08 34.1 0.5 3.5e-07 30.2 0.1 2.5 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 CAR21818.1 - 6.2e-08 32.8 0.1 6.4e-05 23.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RHD_dimer PF16179.5 CAR21818.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.8 1 0 0 1 1 1 0 Rel homology dimerisation domain Pes-10 PF07149.11 CAR21818.1 - 6.3 5.7 9.5 16 4.4 9.5 1.6 1 0 0 1 1 1 0 Pes-10 PPTA PF01239.22 CAR21819.1 - 1.4e-39 132.7 19.1 6.1e-09 35.3 0.2 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DSPc PF00782.20 CAR21820.1 - 6.6e-25 87.5 0.3 7.9e-24 84.0 0.3 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR21820.1 - 0.00052 19.7 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.14 CAR21820.1 - 0.0076 16.4 1.0 0.038 14.2 1.0 2.1 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.13 CAR21820.1 - 0.065 13.3 0.2 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like RIG-I_C-RD PF11648.8 CAR21820.1 - 0.19 12.0 1.8 1 9.6 0.1 2.4 2 0 0 2 2 2 0 C-terminal domain of RIG-I zinc_ribbon_6 PF14599.6 CAR21820.1 - 0.41 10.7 0.1 0.41 10.7 0.1 1.9 2 0 0 2 2 2 0 Zinc-ribbon Zn_ribbon_SprT PF17283.2 CAR21820.1 - 0.96 9.4 0.0 0.96 9.4 0.0 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain UPF0547 PF10571.9 CAR21820.1 - 5.7 7.1 8.1 12 6.0 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Apc15p PF05841.11 CAR21821.1 - 1.1e-16 61.7 1.2 2.7e-16 60.5 0.5 2.0 1 1 1 2 2 2 1 Apc15p protein DUF1748 PF08520.10 CAR21822.1 - 1.9e-07 30.9 0.1 2.5e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.32 CAR21823.1 - 1.6e-11 44.6 0.6 0.0002 22.1 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21823.1 - 3.8e-06 27.1 0.0 0.016 15.5 0.0 3.7 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR21823.1 - 0.00075 19.4 0.0 0.017 15.0 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.9 CAR21823.1 - 0.0011 18.3 0.0 0.0071 15.6 0.0 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller AAA_12 PF13087.6 CAR21824.1 - 7.3e-58 195.5 0.0 1.8e-57 194.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR21824.1 - 1.1e-56 192.5 0.4 1.9e-56 191.8 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR21824.1 - 2.8e-14 53.7 0.0 4.9e-13 49.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR21824.1 - 1.5e-12 47.7 0.0 7.9e-11 42.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAR21824.1 - 4e-08 33.3 0.3 0.25 11.0 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CAR21824.1 - 1.1e-06 28.4 0.0 4.7e-06 26.4 0.0 1.9 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CAR21824.1 - 7.9e-06 26.0 0.0 2.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR21824.1 - 3.9e-05 23.9 0.2 0.0016 18.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain Helicase_RecD PF05127.14 CAR21824.1 - 0.00039 20.3 0.0 0.0017 18.2 0.0 2.3 2 1 0 2 2 1 1 Helicase DEAD PF00270.29 CAR21824.1 - 0.00081 19.2 0.3 0.0079 16.0 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 CAR21824.1 - 0.0056 16.1 0.0 0.016 14.7 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein DUF853 PF05872.12 CAR21824.1 - 0.0057 15.3 0.0 0.0095 14.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 CAR21824.1 - 0.006 17.0 0.0 0.014 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CAR21824.1 - 0.0063 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein PIF1 PF05970.14 CAR21824.1 - 0.0067 15.6 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase AAA_24 PF13479.6 CAR21824.1 - 0.008 15.9 0.0 0.03 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CAR21824.1 - 0.0083 16.6 0.2 0.031 14.7 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CAR21824.1 - 0.0087 16.6 5.2 1.2 9.6 2.5 2.4 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 CAR21824.1 - 0.014 15.3 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 CAR21824.1 - 0.016 14.5 0.2 0.05 12.8 0.0 1.9 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 CAR21824.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_31 PF13614.6 CAR21824.1 - 0.028 14.3 0.1 0.058 13.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CAR21824.1 - 0.033 14.1 0.1 2.8 7.8 0.0 2.8 1 1 1 2 2 2 0 Rad17 P-loop domain LEDGF PF11467.8 CAR21824.1 - 0.044 13.4 0.3 0.16 11.6 0.3 1.9 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) CmcI PF04989.12 CAR21824.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase AAA_33 PF13671.6 CAR21824.1 - 0.083 13.0 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF1283 PF06932.11 CAR21824.1 - 0.086 13.1 0.8 0.2 11.9 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1283) UvrD_C PF13361.6 CAR21824.1 - 0.087 12.2 1.1 1.7 7.9 1.2 2.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 CAR21824.1 - 0.088 12.8 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zot PF05707.12 CAR21824.1 - 0.14 11.8 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Fer4_NifH PF00142.18 CAR21824.1 - 0.16 11.4 0.0 0.43 10.0 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Kri1_C PF12936.7 CAR21824.1 - 0.75 10.0 3.6 2.5 8.4 3.6 1.8 1 0 0 1 1 1 0 KRI1-like family C-terminal Mt_ATP-synt_D PF05873.12 CAR21825.1 - 1.5e-20 73.6 6.5 2e-20 73.2 6.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) COG6 PF06419.11 CAR21825.1 - 0.0019 16.5 1.3 0.0022 16.3 1.3 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF4201 PF13870.6 CAR21825.1 - 0.0045 16.7 1.0 0.032 14.0 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) LTXXQ PF07813.12 CAR21825.1 - 0.0059 17.3 1.2 1.3 9.8 0.5 2.1 2 0 0 2 2 2 1 LTXXQ motif family protein Dor1 PF04124.12 CAR21825.1 - 0.03 13.0 1.9 0.039 12.6 1.9 1.2 1 0 0 1 1 1 0 Dor1-like family Herpes_UL47 PF03362.13 CAR21825.1 - 0.032 13.0 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein DUF2408 PF10303.9 CAR21825.1 - 0.042 14.4 3.5 0.12 12.9 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) GIDA_assoc PF13932.6 CAR21825.1 - 0.058 13.6 1.0 0.07 13.3 1.0 1.1 1 0 0 1 1 1 0 GidA associated domain Pet20 PF08692.10 CAR21825.1 - 0.077 13.7 0.1 0.13 13.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial protein Pet20 TPR_MLP1_2 PF07926.12 CAR21825.1 - 0.36 10.9 7.2 2.4 8.2 6.7 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 CAR21825.1 - 0.39 11.2 5.1 0.32 11.5 3.5 1.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Fungal_trans PF04082.18 CAR21826.1 - 1.6e-16 60.1 0.0 3.5e-16 59.0 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21826.1 - 2.7e-09 37.0 8.3 4.7e-09 36.2 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.8 CAR21827.1 - 1.7e-88 297.2 3.5 1.7e-88 297.2 3.5 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CAR21827.1 - 6.2e-46 156.5 0.2 6.2e-46 156.5 0.2 2.5 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 DUF5321 PF17254.2 CAR21828.1 - 1.8e-06 27.5 0.7 1.8e-06 27.5 0.7 2.2 1 1 2 3 3 3 1 Family of unknown function (DUF5321) Fungal_trans PF04082.18 CAR21829.1 - 4e-21 75.3 0.3 4e-21 75.3 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21829.1 - 8.1e-06 25.9 8.4 1.5e-05 25.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF-3_zeta PF05091.12 CAR21829.1 - 0.11 11.4 9.3 0.22 10.5 9.3 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ARPC4 PF05856.12 CAR21830.1 - 3.9e-72 241.3 5.7 4.3e-72 241.2 5.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) TpcC PF12642.7 CAR21830.1 - 0.11 12.2 1.5 3 7.6 0.1 2.2 2 0 0 2 2 2 0 Conjugative transposon protein TcpC FF PF01846.19 CAR21831.1 - 4.8e-41 138.7 17.9 3.1e-13 49.7 0.2 5.1 5 0 0 5 5 5 4 FF domain WW PF00397.26 CAR21831.1 - 3.3e-18 65.5 15.8 1e-09 38.3 1.5 3.0 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 CAR21831.1 - 4e-05 23.9 6.8 0.02 15.2 0.2 3.3 2 1 1 3 3 3 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 CAR21831.1 - 0.00029 20.6 1.1 0.58 10.2 0.0 2.5 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 CAR21831.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain RNase_E_G PF10150.9 CAR21831.1 - 0.077 12.4 6.9 3.4 7.0 0.0 3.4 2 1 1 4 4 4 0 Ribonuclease E/G family Peptidase_S24 PF00717.23 CAR21832.1 - 5.7e-08 32.6 0.0 9.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like NAD_binding_10 PF13460.6 CAR21833.1 - 3e-40 138.1 0.0 3.4e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CAR21833.1 - 3.5e-13 49.7 0.0 1.2e-12 47.9 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CAR21833.1 - 4.9e-08 32.3 0.2 7.2e-08 31.8 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CAR21833.1 - 7.8e-07 28.8 0.1 3.1e-05 23.6 0.1 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 CAR21833.1 - 5.6e-05 23.3 0.1 0.00016 21.8 0.2 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 CAR21833.1 - 0.00081 19.8 0.1 0.0011 19.3 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PGK PF00162.19 CAR21833.1 - 0.0056 15.7 0.1 0.0075 15.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoglycerate kinase Ldh_1_N PF00056.23 CAR21833.1 - 0.014 15.5 0.3 0.021 14.9 0.3 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain TrkA_N PF02254.18 CAR21833.1 - 0.042 14.1 0.3 0.095 13.0 0.2 1.6 1 1 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 CAR21833.1 - 0.06 13.6 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CAR21833.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ydc2-catalyt PF09159.10 CAR21834.1 - 2.1e-45 155.6 0.0 3.9e-45 154.7 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 CAR21834.1 - 0.11 12.6 0.0 14 5.8 0.0 2.6 2 1 0 2 2 2 0 Poxvirus A22 protein SeqA_N PF17206.3 CAR21835.1 - 0.065 12.6 1.8 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 SeqA protein N-terminal domain Tab2_like PF06485.11 CAR21835.1 - 0.078 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Flavoprotein PF02441.19 CAR21836.1 - 4.7e-53 179.2 0.0 7e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DNA_pol_phi PF04931.13 CAR21836.1 - 0.12 10.5 20.0 0.17 10.0 20.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CAR21836.1 - 2.3 6.3 15.9 3.3 5.8 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 CAR21836.1 - 4.3 6.4 25.5 9.4 5.3 25.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ferric_reduct PF01794.19 CAR21837.1 - 4.1e-22 78.6 11.5 4.1e-22 78.6 11.5 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CAR21837.1 - 3.2e-20 72.2 0.0 6.8e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CAR21837.1 - 4.1e-20 72.5 0.0 7.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF5475 PF17569.2 CAR21837.1 - 0.03 14.6 0.2 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5475) CFEM PF05730.11 CAR21837.1 - 1.3 9.2 4.9 0.16 12.1 0.5 1.8 2 0 0 2 2 2 0 CFEM domain zf-Tim10_DDP PF02953.15 CAR21838.1 - 2.8e-21 74.9 2.8 3.5e-21 74.6 2.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phage_DsbA PF11126.8 CAR21838.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 2 0 0 2 2 2 0 Transcriptional regulator DsbA Cyto_heme_lyase PF01265.17 CAR21839.1 - 1.1e-45 156.5 8.0 2.4e-44 152.1 8.0 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase G-alpha PF00503.20 CAR21840.1 - 4.3e-112 374.8 0.8 5.8e-112 374.4 0.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CAR21840.1 - 9.3e-16 57.8 1.3 5.4e-10 39.0 0.0 2.9 2 1 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR21840.1 - 0.00074 18.9 0.1 0.076 12.3 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TniB PF05621.11 CAR21840.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 CAR21840.1 - 0.076 13.1 0.0 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CAR21840.1 - 0.096 12.0 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ParBc PF02195.18 CAR21841.1 - 3.9e-14 52.7 0.0 4.9e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain CBM46 PF18448.1 CAR21842.1 - 0.045 14.1 0.1 0.088 13.1 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain Ldh_1_C PF02866.18 CAR21843.1 - 1e-54 185.0 0.0 2.9e-54 183.5 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CAR21843.1 - 2.1e-44 151.1 0.2 3e-44 150.5 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CAR21843.1 - 2.3e-05 23.6 0.0 3.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CHY PF05495.12 CAR21844.1 - 3e-12 46.9 10.7 4.1e-12 46.4 10.7 1.2 1 0 0 1 1 1 1 CHY zinc finger Rhodanese_C PF12368.8 CAR21844.1 - 3.7 8.0 13.0 1.5 9.3 5.3 2.5 1 1 1 2 2 2 0 Rhodanase C-terminal Ank_2 PF12796.7 CAR21845.1 - 3.7e-21 75.5 11.9 5.7e-09 36.5 1.5 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR21845.1 - 1.8e-20 73.0 4.4 3.3e-09 37.1 0.2 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CAR21845.1 - 4.4e-10 39.6 13.2 0.11 13.0 0.5 5.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CAR21845.1 - 4.7e-09 35.7 9.0 0.39 11.4 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CAR21845.1 - 4.3e-05 23.7 2.4 0.052 13.9 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Poxvirus_B22R PF04395.12 CAR21845.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein Abhydrolase_1 PF00561.20 CAR21846.1 - 6.9e-24 84.9 0.0 2.1e-23 83.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR21846.1 - 4.5e-12 47.1 0.0 7e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR21846.1 - 8.3e-12 44.9 0.0 1.5e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 CAR21846.1 - 7.5e-07 28.1 0.0 2.7e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Ndr family Esterase PF00756.20 CAR21846.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 CAR21846.1 - 0.00028 20.8 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 CAR21846.1 - 0.00029 20.5 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 CAR21846.1 - 0.0033 17.3 0.0 0.0075 16.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 CAR21846.1 - 0.0052 16.7 0.0 0.012 15.5 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CAR21846.1 - 0.0069 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 CAR21846.1 - 0.028 14.3 0.0 5 7.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 CAR21846.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 CAR21846.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) TUG-UBL1 PF11470.8 CAR21847.1 - 4.4e-21 74.9 0.1 1.4e-20 73.3 0.1 1.9 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 CAR21847.1 - 2.5e-13 50.0 0.0 5.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain MCR_beta_N PF02783.15 CAR21847.1 - 0.12 12.0 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain PPR_3 PF13812.6 CAR21848.1 - 0.0016 18.5 1.1 0.55 10.3 0.1 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain NuiA PF07924.11 CAR21848.1 - 0.09 13.2 0.7 0.25 11.8 0.2 2.1 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein SURF6 PF04935.12 CAR21849.1 - 3.3e-45 154.4 45.4 3.3e-45 154.4 45.4 3.1 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 CAR21849.1 - 4.9e-14 52.7 4.3 4.9e-14 52.7 4.3 6.2 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 Lentiviral_Tat PF02998.14 CAR21849.1 - 0.38 10.8 5.4 1.3 9.1 5.4 1.9 1 0 0 1 1 1 0 Lentiviral Tat protein EF1G PF00647.19 CAR21850.1 - 2.4e-43 146.6 0.0 1e-42 144.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CAR21850.1 - 3e-12 46.7 0.0 1e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CAR21850.1 - 3.9e-11 43.0 0.1 3.9e-11 43.0 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR21850.1 - 2.1e-06 27.7 0.2 6.1e-06 26.2 0.2 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAR21850.1 - 8.3e-06 26.1 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR21850.1 - 0.00056 20.1 0.1 0.00056 20.1 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 CAR21850.1 - 5.4 7.7 5.0 13 6.4 5.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain V-ATPase_C PF03223.15 CAR21851.1 - 1.1e-122 410.0 0.6 1.3e-122 409.8 0.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NECFESHC PF16621.5 CAR21852.1 - 0.15 12.1 0.2 0.15 12.1 0.2 1.8 2 0 0 2 2 2 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 PepSY_TM PF03929.16 CAR21853.1 - 0.44 10.2 6.9 0.075 12.7 1.4 2.0 2 0 0 2 2 2 0 PepSY-associated TM region R3H-assoc PF13902.6 CAR21853.1 - 4.1 7.8 7.3 5.9 7.3 6.8 1.6 1 1 0 1 1 1 0 R3H-associated N-terminal domain TDA11 PF17084.5 CAR21854.1 - 4.4e-52 177.6 34.2 5.2e-26 91.6 11.0 3.1 1 1 1 2 2 2 2 Topoisomerase I damage affected protein 11 Peptidase_S41 PF03572.18 CAR21854.1 - 0.029 14.0 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S41 FAM76 PF16046.5 CAR21854.1 - 0.42 9.9 15.6 0.045 13.1 11.3 1.5 2 0 0 2 2 2 0 FAM76 protein IL32 PF15225.6 CAR21854.1 - 0.6 10.5 2.3 33 4.9 0.2 2.8 3 0 0 3 3 3 0 Interleukin 32 SlyX PF04102.12 CAR21854.1 - 1.3 9.7 7.6 2.4 8.8 6.5 2.1 1 1 0 1 1 1 0 SlyX SKA1 PF07160.12 CAR21854.1 - 4 7.2 16.7 0.21 11.4 10.9 1.9 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Kelch_3 PF13415.6 CAR21855.1 - 2e-29 101.3 4.9 5.1e-05 23.5 0.0 6.5 7 0 0 7 7 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CAR21855.1 - 2.7e-27 94.3 10.5 4.3e-05 23.4 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CAR21855.1 - 6.1e-24 83.5 9.6 0.00013 22.2 0.1 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_4 PF13418.6 CAR21855.1 - 1.8e-23 82.3 14.7 0.00018 21.4 0.1 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 CAR21855.1 - 2.4e-16 59.0 5.2 2.9e-05 23.5 0.0 6.2 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CAR21855.1 - 2.4e-12 46.3 11.0 0.13 12.3 0.0 6.8 6 1 0 6 6 6 4 Kelch motif TPR_MLP1_2 PF07926.12 CAR21855.1 - 0.00027 21.0 12.0 0.00027 21.0 12.0 4.5 4 1 0 4 4 4 1 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 CAR21855.1 - 0.0017 18.4 4.3 0.0017 18.4 4.3 4.4 4 1 1 5 5 3 1 Centrosome localisation domain of PPC89 Syntaxin-6_N PF09177.11 CAR21855.1 - 0.01 16.3 5.8 0.01 16.3 5.8 3.6 3 1 0 4 4 3 0 Syntaxin 6, N-terminal ApoO PF09769.9 CAR21855.1 - 1.5 8.8 3.5 8.8 6.3 0.4 3.0 3 0 0 3 3 3 0 Apolipoprotein O Vac_Fusion PF02346.16 CAR21855.1 - 2.3 7.9 3.9 9.8 5.9 0.4 3.2 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 APC_N_CC PF16689.5 CAR21855.1 - 6.4 6.9 11.4 12 6.1 1.4 3.7 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain MAD PF05557.13 CAR21855.1 - 7.7 4.7 41.9 1.7e+02 0.3 41.9 2.9 1 1 0 1 1 1 0 Mitotic checkpoint protein HrpB7 PF09486.10 CAR21855.1 - 8.3 6.8 18.7 12 6.3 6.8 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) REC104 PF17378.2 CAR21856.1 - 0.0002 21.3 0.1 0.00033 20.5 0.1 1.3 1 0 0 1 1 1 1 Meiotic recombination protein REC104 CODH_A_N PF18537.1 CAR21858.1 - 0.062 13.3 0.0 0.096 12.7 0.0 1.4 1 1 0 1 1 1 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain DUF4553 PF15090.6 CAR21858.1 - 0.11 11.4 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) ApoO PF09769.9 CAR21859.1 - 3.2e-29 101.5 0.0 5.8e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein O RTT107_BRCT_6 PF16771.5 CAR21860.1 - 3e-36 124.0 1.3 5.2e-36 123.3 0.4 2.0 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CAR21860.1 - 2.1e-25 88.5 0.1 5e-23 80.9 0.0 3.7 3 1 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CAR21860.1 - 1.9e-17 62.9 3.2 5.6e-14 51.8 0.1 3.5 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.26 CAR21860.1 - 8.9e-15 54.8 3.5 2.3e-05 24.7 0.0 4.9 5 1 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CAR21860.1 - 2.4e-10 40.7 1.0 0.1 13.0 0.0 4.6 4 1 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CAR21860.1 - 0.034 14.5 4.1 6.1 7.2 0.2 4.2 4 0 0 4 4 4 0 DNA ligase 3 BRCT domain Ank_2 PF12796.7 CAR21861.1 - 1.4e-28 99.3 0.3 1.3e-13 51.3 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 CAR21861.1 - 1.8e-20 74.3 12.2 2.1e-09 37.8 0.7 3.2 1 1 2 3 3 3 3 SPX domain Ank_4 PF13637.6 CAR21861.1 - 1.6e-19 70.0 2.2 9.5e-06 26.1 0.0 5.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CAR21861.1 - 1.1e-18 66.8 0.6 2e-05 24.8 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 CAR21861.1 - 1.1e-17 62.3 2.3 0.0016 18.8 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CAR21861.1 - 1e-15 57.6 1.6 0.0086 16.4 0.0 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) GDPD PF03009.17 CAR21861.1 - 2e-06 27.7 0.0 1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CAR21862.1 - 8.6e-40 135.2 0.0 2.3e-11 44.1 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR21862.1 - 5e-26 90.4 0.0 6.3e-07 29.6 0.0 5.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR21862.1 - 5.2e-25 84.8 0.0 0.0016 18.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 CAR21862.1 - 1.6e-23 82.7 0.8 3.7e-08 33.8 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CAR21862.1 - 2e-23 81.7 0.3 9.9e-05 22.6 0.0 5.6 5 1 1 6 6 6 4 Ankyrin repeat Band_7 PF01145.25 CAR21863.1 - 7.2e-21 75.0 2.1 7.2e-21 75.0 2.1 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.19 CAR21863.1 - 0.02 14.4 0.9 0.028 13.9 0.9 1.2 1 0 0 1 1 1 0 MraW methylase family Spo12 PF05032.12 CAR21864.1 - 1.1e-19 70.0 4.5 1.1e-19 70.0 4.5 1.7 2 0 0 2 2 2 1 Spo12 family SMI1_KNR4 PF09346.10 CAR21867.1 - 7.5e-34 117.0 0.0 1.2e-32 113.1 0.0 2.5 1 1 1 2 2 2 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 CAR21867.1 - 0.095 13.1 0.0 32 5.0 0.0 2.9 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall DIE2_ALG10 PF04922.12 CAR21868.1 - 2.1e-109 366.4 35.2 2.7e-109 366.1 35.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Lectin_C PF00059.21 CAR21869.1 - 0.011 16.4 6.0 0.034 14.9 3.3 2.8 3 0 0 3 3 3 0 Lectin C-type domain Pex24p PF06398.11 CAR21870.1 - 1.5e-73 248.0 0.1 2.1e-73 247.5 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.17 CAR21870.1 - 0.0085 16.1 1.2 0.46 10.4 0.1 2.7 2 1 0 3 3 3 1 Reticulon PRT_C PF08372.10 CAR21870.1 - 0.02 14.7 0.3 0.046 13.5 0.1 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 CAR21870.1 - 0.088 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF5398 PF17376.2 CAR21870.1 - 0.089 13.4 0.1 0.34 11.6 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5398) WD40 PF00400.32 CAR21871.1 - 6e-11 42.7 4.7 0.22 12.5 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21871.1 - 0.00071 19.8 0.0 17 5.8 0.0 4.3 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR21871.1 - 0.04 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CAR21872.1 - 0.0012 19.1 0.0 2 8.8 0.0 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR21872.1 - 0.0015 19.3 0.1 0.48 11.4 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CAR21872.1 - 0.008 15.3 0.3 0.021 13.9 0.0 1.7 3 0 0 3 3 3 1 Coatomer WD associated region SKG6 PF08693.10 CAR21874.1 - 2e-10 39.9 6.8 3.5e-10 39.1 6.8 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 CAR21874.1 - 0.0015 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 CAR21874.1 - 0.0063 16.4 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 TMEM154 protein family DUF1180 PF06679.12 CAR21874.1 - 0.037 14.5 0.4 0.037 14.5 0.4 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) DUF3377 PF11857.8 CAR21874.1 - 0.044 13.7 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) TRP PF06011.12 CAR21874.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ribosomal_S4 PF00163.19 CAR21875.1 - 1.9e-12 47.9 2.4 2.2e-12 47.7 1.8 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CAR21875.1 - 9.8e-12 44.4 0.0 2.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain Pox_A_type_inc PF04508.12 CAR21875.1 - 0.71 9.8 2.6 1.2 9.1 0.6 2.4 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_L6 PF00347.23 CAR21876.1 - 3.8e-24 85.2 0.3 4.2e-13 49.8 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.22 CAR21877.1 - 7.3e-17 61.4 1.4 9.3e-15 54.5 0.3 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 CRM1_C PF08767.11 CAR21878.1 - 1.6e-131 438.3 6.4 2e-131 437.9 2.7 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 CAR21878.1 - 4.6e-37 127.4 7.0 4.6e-37 127.4 7.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CAR21878.1 - 8.2e-32 108.7 1.0 2.6e-31 107.0 1.0 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CAR21878.1 - 2.3e-29 101.3 0.5 1.5e-28 98.6 0.5 2.6 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CAR21878.1 - 5.2e-16 57.9 0.6 5.2e-16 57.9 0.6 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CAR21878.1 - 1.2e-15 57.2 0.0 5.3e-15 55.1 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 CAR21878.1 - 0.00083 19.3 0.6 0.08 12.8 0.0 3.6 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) DUF2294 PF10057.9 CAR21878.1 - 0.043 13.9 0.2 4.3 7.5 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) BID PF06393.11 CAR21878.1 - 0.074 12.6 0.3 0.27 10.8 0.3 1.9 1 0 0 1 1 1 0 BH3 interacting domain (BID) Symplekin_C PF12295.8 CAR21878.1 - 0.092 12.8 4.7 3.1 7.9 0.0 4.8 5 0 0 5 5 5 0 Symplekin tight junction protein C terminal FNIP_C PF14638.6 CAR21878.1 - 0.26 10.9 3.3 0.73 9.4 1.8 2.2 2 0 0 2 2 2 0 Folliculin-interacting protein C-terminus Ion_trans PF00520.31 CAR21879.1 - 7.7e-102 339.7 92.6 2.5e-36 125.1 9.1 5.0 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CAR21879.1 - 0.00026 19.8 5.1 0.00026 19.8 5.1 7.1 6 2 2 8 8 8 4 Polycystin cation channel Gpi1 PF05024.15 CAR21880.1 - 5.7e-61 205.9 15.1 5.7e-61 205.9 15.1 2.1 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3975 PF13126.6 CAR21880.1 - 0.051 14.0 1.5 0.64 10.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) MRP-S33 PF08293.11 CAR21881.1 - 1.6e-32 111.5 0.1 2.4e-32 111.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ribosomal_S2 PF00318.20 CAR21882.1 - 8.7e-24 83.9 0.1 1.7e-13 50.3 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 CAR21882.1 - 0.00053 21.3 8.5 0.001 20.4 8.5 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ferric_reduct PF01794.19 CAR21883.1 - 1.1e-20 74.0 16.0 1.1e-20 74.0 16.0 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CAR21883.1 - 0.00085 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CAR21883.1 - 0.048 13.8 0.0 0.17 12.0 0.0 1.9 1 1 0 1 1 1 0 Ferric reductase NAD binding domain LicD PF04991.13 CAR21884.1 - 7.8e-17 62.2 4.4 1.6e-14 54.6 0.1 3.2 2 1 0 2 2 2 1 LicD family DUF758 PF05527.11 CAR21884.1 - 0.11 12.5 1.6 0.13 12.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF758) AATase PF07247.12 CAR21885.1 - 1.4e-48 165.7 0.0 3.9e-48 164.2 0.0 1.7 1 1 0 1 1 1 1 Alcohol acetyltransferase Tri3 PF07428.11 CAR21885.1 - 0.021 13.7 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Condensation PF00668.20 CAR21885.1 - 0.059 12.0 0.0 1.3 7.6 0.0 2.0 2 0 0 2 2 2 0 Condensation domain zf-ZPR1 PF03367.13 CAR21886.1 - 3.6e-114 377.9 3.1 8.6e-57 191.4 0.2 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 CAR21886.1 - 1.3 9.1 4.8 1.2 9.2 0.6 2.5 2 1 0 2 2 2 0 zinc-ribbons OrfB_Zn_ribbon PF07282.11 CAR21886.1 - 3 7.8 5.3 21 5.1 0.1 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.7 CAR21886.1 - 4.6 7.4 11.0 17 5.5 3.8 3.7 3 1 0 3 3 3 0 Double zinc ribbon zf-H2C2_2 PF13465.6 CAR21886.1 - 6.1 7.5 6.6 22 5.7 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain Glyco_hydro_125 PF06824.11 CAR21888.1 - 1.6e-168 560.9 0.0 1.9e-168 560.7 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Pigment_DH PF06324.11 CAR21888.1 - 0.44 10.7 2.0 5.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Pigment-dispersing hormone (PDH) EMC3_TMCO1 PF01956.16 CAR21889.1 - 5.2e-53 179.3 1.5 6.3e-53 179.0 1.5 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ATP_bind_1 PF03029.17 CAR21890.1 - 3.8e-80 269.2 0.1 3.8e-80 269.2 0.1 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CAR21890.1 - 1.2e-07 31.5 2.1 8.8e-07 28.6 0.1 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CAR21890.1 - 0.00013 21.7 0.1 0.001 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR21890.1 - 0.00019 21.6 0.0 0.00058 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAR21890.1 - 0.00021 21.4 0.0 0.0089 16.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR21890.1 - 0.00048 19.7 0.0 0.013 15.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR21890.1 - 0.00056 19.8 0.1 2.4 8.0 0.0 3.4 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CAR21890.1 - 0.00099 19.4 0.0 0.0049 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CAR21890.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain CLP1_P PF16575.5 CAR21890.1 - 0.0026 17.6 0.0 2.8 7.7 0.0 2.7 3 0 0 3 3 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop PduV-EutP PF10662.9 CAR21890.1 - 0.0026 17.5 0.0 0.067 12.9 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CAR21890.1 - 0.0035 17.7 0.0 0.027 14.9 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 CAR21890.1 - 0.006 16.7 0.5 5.2 7.1 1.0 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_18 PF13238.6 CAR21890.1 - 0.006 17.1 1.8 0.017 15.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 CAR21890.1 - 0.0066 15.5 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 CAR21890.1 - 0.0097 15.6 0.0 0.16 11.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.19 CAR21890.1 - 0.011 15.3 0.2 0.17 11.5 0.2 2.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CAR21890.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 CAR21890.1 - 0.014 15.1 0.4 0.16 11.7 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 CAR21890.1 - 0.016 14.4 0.2 0.058 12.6 0.0 2.0 2 1 1 3 3 3 0 NB-ARC domain SRPRB PF09439.10 CAR21890.1 - 0.022 14.2 0.1 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 CAR21890.1 - 0.025 14.3 1.0 0.67 9.6 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Roc PF08477.13 CAR21890.1 - 0.034 14.4 0.0 1.4 9.1 0.0 2.8 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CAR21890.1 - 0.068 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CAR21890.1 - 0.075 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Arf PF00025.21 CAR21890.1 - 0.087 12.3 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family KAP_NTPase PF07693.14 CAR21890.1 - 0.088 12.0 0.0 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain ATP-synt_E PF05680.12 CAR21890.1 - 1.2 9.5 5.6 3 8.3 5.6 1.6 1 0 0 1 1 1 0 ATP synthase E chain PAC2 PF09754.9 CAR21891.1 - 3.8e-24 85.9 0.0 5.4e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 PAC2 family DUF2066 PF09839.9 CAR21891.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) HEAT_2 PF13646.6 CAR21892.1 - 8e-31 106.3 0.1 1.2e-14 54.5 0.1 3.2 2 2 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CAR21892.1 - 5.9e-17 60.6 0.2 0.0009 19.7 0.0 6.6 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 CAR21892.1 - 1.9e-10 40.1 0.3 0.15 12.4 0.1 5.6 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 CAR21892.1 - 5e-06 26.4 0.1 0.017 15.1 0.0 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CAR21892.1 - 0.00021 21.7 0.8 0.27 11.8 0.1 4.0 4 1 1 5 5 5 2 HEAT-like repeat Ham1p_like PF01725.16 CAR21893.1 - 1.3e-51 175.2 0.0 1.4e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Xpo1 PF08389.12 CAR21894.1 - 4.7e-38 130.6 0.7 4.7e-38 130.6 0.7 3.7 4 0 0 4 4 4 1 Exportin 1-like protein AAA PF00004.29 CAR21896.1 - 4.9e-16 59.4 0.0 2e-15 57.4 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CAR21896.1 - 7e-15 55.2 0.0 1.5e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CAR21896.1 - 6.2e-14 52.1 0.0 4.1e-12 46.2 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CAR21896.1 - 5.9e-09 36.1 0.0 1e-08 35.3 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CAR21896.1 - 1.5e-06 28.5 0.7 0.00033 20.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CAR21896.1 - 7.3e-06 25.8 0.1 3.1e-05 23.8 0.0 2.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_11 PF13086.6 CAR21896.1 - 2.7e-05 24.1 0.1 4.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAR21896.1 - 3.6e-05 24.2 0.2 0.0028 18.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 CAR21896.1 - 9.1e-05 22.3 0.0 0.0025 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CAR21896.1 - 0.00019 21.4 0.0 0.00081 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAR21896.1 - 0.00024 20.6 0.0 0.0063 15.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 CAR21896.1 - 0.0005 20.1 0.0 0.0098 15.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_assoc_2 PF16193.5 CAR21896.1 - 0.00073 19.8 0.1 0.0019 18.5 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CAR21896.1 - 0.00088 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_24 PF13479.6 CAR21896.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR21896.1 - 0.0012 19.1 0.2 0.035 14.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CAR21896.1 - 0.0027 16.9 0.0 0.0056 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CAR21896.1 - 0.0046 16.5 0.1 0.01 15.3 0.0 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 CAR21896.1 - 0.011 15.8 0.0 0.038 14.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 CAR21896.1 - 0.024 13.9 0.0 0.13 11.5 0.0 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 CAR21896.1 - 0.052 14.0 0.0 0.088 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAR21896.1 - 0.1 13.0 0.1 0.52 10.7 0.0 2.2 2 1 1 3 3 3 0 RNA helicase AAA_18 PF13238.6 CAR21896.1 - 0.11 13.1 0.0 0.32 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CAR21896.1 - 0.12 12.2 0.1 1.7 8.5 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAR21896.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Yae1_N PF09811.9 CAR21897.1 - 7e-12 44.9 1.4 7e-12 44.9 1.4 1.5 2 0 0 2 2 2 1 Essential protein Yae1, N terminal FAT PF02259.23 CAR21898.1 - 8.9e-136 452.7 2.1 1.5e-135 451.9 0.0 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CAR21898.1 - 9.4e-74 248.4 0.0 1.8e-73 247.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CAR21898.1 - 4.3e-67 225.0 22.0 7.5e-65 217.8 0.6 5.9 6 2 1 7 7 7 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CAR21898.1 - 5.6e-43 145.4 2.6 1.6e-42 143.9 0.4 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 CAR21898.1 - 4.8e-17 61.5 0.4 1.2e-16 60.2 0.4 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CAR21898.1 - 5.1e-09 36.4 9.0 0.2 12.0 0.0 8.6 8 1 0 8 8 8 2 HEAT repeats HEAT_EZ PF13513.6 CAR21898.1 - 8.3e-08 32.6 5.3 0.056 14.0 0.0 9.1 8 1 2 10 10 10 2 HEAT-like repeat HEAT PF02985.22 CAR21898.1 - 1.1e-06 28.3 10.7 0.06 13.6 0.0 8.0 9 0 0 9 9 7 2 HEAT repeat IFRD PF05004.13 CAR21898.1 - 0.00046 19.4 3.8 0.025 13.7 0.2 4.3 4 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 CAR21898.1 - 0.012 16.2 5.1 9.4 6.9 0.0 5.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HSM3_C PF18794.1 CAR21898.1 - 0.024 14.2 0.6 0.13 11.9 0.2 2.6 2 0 0 2 2 2 0 DNA mismatch repair protein HSM3, C terminal domain CLASP_N PF12348.8 CAR21898.1 - 1.6 8.2 8.6 0.67 9.5 0.1 4.4 5 1 0 6 6 6 0 CLASP N terminal MMS19_N PF14500.6 CAR21898.1 - 2.9 7.4 6.7 3.2 7.3 0.5 3.7 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Actin PF00022.19 CAR21899.1 - 2.6e-91 306.3 0.0 6.8e-89 298.3 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAR21899.1 - 0.00037 19.4 0.0 0.13 11.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CAR21899.1 - 0.0039 17.6 0.0 0.0093 16.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein FtsA Cpn60_TCP1 PF00118.24 CAR21900.1 - 2e-152 508.3 4.1 2.3e-152 508.1 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TFIIS_C PF01096.18 CAR21901.1 - 1.7e-18 66.1 8.8 2.1e-18 65.9 1.5 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CAR21901.1 - 6.3e-13 48.4 8.8 2.8e-10 39.9 0.4 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 CAR21901.1 - 1.5e-05 24.9 7.6 0.004 17.1 0.4 2.7 2 1 0 2 2 2 2 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 CAR21901.1 - 2e-05 24.5 3.1 0.021 14.8 0.8 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 CAR21901.1 - 0.00027 20.5 11.5 0.38 10.5 1.9 4.2 3 1 0 3 3 3 2 zinc-ribbon domain Mu-like_Com PF10122.9 CAR21901.1 - 0.00093 18.6 0.9 0.29 10.6 0.3 2.4 2 0 0 2 2 2 1 Mu-like prophage protein Com TF_Zn_Ribbon PF08271.12 CAR21901.1 - 0.0014 18.1 11.3 0.11 12.1 2.9 3.3 2 2 1 3 3 3 2 TFIIB zinc-binding zf-RRN7 PF11781.8 CAR21901.1 - 0.0014 18.3 10.9 0.52 10.1 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GATA PF00320.27 CAR21901.1 - 0.0014 18.1 5.9 0.036 13.7 0.2 3.1 3 1 0 3 3 3 1 GATA zinc finger Zn-ribbon_8 PF09723.10 CAR21901.1 - 0.0042 17.2 11.9 0.7 10.1 0.6 3.4 3 0 0 3 3 3 1 Zinc ribbon domain IBR PF01485.21 CAR21901.1 - 0.0047 17.1 4.4 0.27 11.5 0.8 2.4 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 CAR21901.1 - 0.0056 16.0 12.2 2.4 7.7 0.6 4.3 4 0 0 4 4 4 1 zinc-ribbon domain C1_1 PF00130.22 CAR21901.1 - 0.0077 16.1 3.5 0.3 11.0 0.2 2.5 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) eIF-5_eIF-2B PF01873.17 CAR21901.1 - 0.011 15.6 3.4 0.6 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 HypA PF01155.19 CAR21901.1 - 0.017 15.1 7.8 2.4 8.2 7.8 2.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 CAR21901.1 - 0.017 15.0 7.1 10 6.1 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Ogr_Delta PF04606.12 CAR21901.1 - 0.018 15.0 2.6 0.018 15.0 2.6 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger TackOD1 PF18551.1 CAR21901.1 - 0.03 14.0 6.8 0.37 10.4 0.3 2.5 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 OrfB_Zn_ribbon PF07282.11 CAR21901.1 - 0.038 13.9 7.7 0.24 11.4 0.2 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain DpnI PF06044.12 CAR21901.1 - 0.041 13.5 3.2 1.5 8.4 0.2 2.1 1 1 0 2 2 2 0 Dam-replacing family zf-C4_Topoisom PF01396.19 CAR21901.1 - 0.048 13.5 1.8 0.048 13.5 1.8 3.6 3 1 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger Nudix_N_2 PF14803.6 CAR21901.1 - 0.049 13.6 11.9 6.2 6.8 3.3 4.1 3 1 1 4 4 4 0 Nudix N-terminal Lar_restr_allev PF14354.6 CAR21901.1 - 0.083 13.3 9.3 0.95 9.9 0.5 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF2072 PF09845.9 CAR21901.1 - 0.084 13.1 5.6 0.73 10.1 0.1 2.8 1 1 2 3 3 3 0 Zn-ribbon containing protein YhfH PF14149.6 CAR21901.1 - 0.089 12.8 9.9 14 5.8 0.3 4.1 4 0 0 4 4 4 0 YhfH-like protein zf-TFIIB PF13453.6 CAR21901.1 - 0.091 12.1 5.2 0.092 12.1 0.8 2.6 2 1 1 3 3 3 0 Transcription factor zinc-finger Baculo_p48 PF04878.13 CAR21901.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein Baculo_LEF5_C PF11792.8 CAR21901.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.8 4 0 0 4 4 3 0 Baculoviridae late expression factor 5 C-terminal domain Zn_ribbon_recom PF13408.6 CAR21901.1 - 0.19 12.3 7.1 6.4 7.4 0.0 3.6 4 1 0 4 4 3 0 Recombinase zinc beta ribbon domain zf-RING_5 PF14634.6 CAR21901.1 - 0.3 11.1 6.2 2.7 8.0 0.8 2.9 3 0 0 3 3 3 0 zinc-RING finger domain zf-IS66 PF13005.7 CAR21901.1 - 0.4 11.1 9.0 6.4 7.3 0.2 4.0 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-ZPR1 PF03367.13 CAR21901.1 - 0.41 10.5 3.3 0.61 9.9 0.4 2.3 3 0 0 3 3 2 0 ZPR1 zinc-finger domain zf-H2C2_2 PF13465.6 CAR21901.1 - 0.48 11.0 7.3 0.68 10.5 0.1 3.4 4 0 0 4 4 3 0 Zinc-finger double domain zf-AN1 PF01428.16 CAR21901.1 - 0.5 10.6 6.7 19 5.5 0.1 3.5 3 1 0 3 3 3 0 AN1-like Zinc finger zf_UBZ PF18439.1 CAR21901.1 - 0.64 9.7 9.8 24 4.6 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-Mss51 PF13824.6 CAR21901.1 - 0.77 9.9 10.4 2.7 8.1 2.6 3.3 2 2 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3797 PF12677.7 CAR21901.1 - 0.87 9.5 8.7 0.63 10.0 1.3 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF3797) zf-ISL3 PF14690.6 CAR21901.1 - 1 10.1 5.7 2.2 9.0 0.1 3.4 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Elf1 PF05129.13 CAR21901.1 - 1.3 9.2 8.7 1.3 9.2 0.9 2.7 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS91 PF14319.6 CAR21901.1 - 1.3 9.1 8.5 5.8 7.0 2.3 3.0 1 1 0 2 2 2 0 Transposase zinc-binding domain HalOD2 PF18547.1 CAR21901.1 - 1.3 9.0 10.4 18 5.3 0.1 3.6 2 2 1 3 3 3 0 Halobacterial output domain 2 CpXC PF14353.6 CAR21901.1 - 1.4 9.0 10.4 1.3 9.0 0.8 3.4 2 1 2 4 4 4 0 CpXC protein Rubredoxin PF00301.20 CAR21901.1 - 1.7 8.7 8.1 35 4.5 0.0 3.5 4 0 0 4 4 3 0 Rubredoxin zf-tcix PF14952.6 CAR21901.1 - 2 8.1 10.4 7.7 6.2 0.3 3.9 4 0 0 4 4 4 0 Putative treble-clef, zinc-finger, Zn-binding DUF35_N PF12172.8 CAR21901.1 - 3.1 7.8 8.9 13 5.8 0.1 3.7 4 0 0 4 4 4 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Rubredoxin_2 PF18073.1 CAR21901.1 - 3.4 7.5 21.4 3.2 7.6 0.4 4.1 4 0 0 4 4 4 0 Rubredoxin metal binding domain DNA_RNApol_7kD PF03604.13 CAR21901.1 - 4.5 7.0 16.7 20 5.0 0.7 4.1 3 1 2 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_7 PF02591.15 CAR21901.1 - 4.6 7.5 11.0 53 4.1 1.7 4.1 4 1 0 4 4 4 0 C4-type zinc ribbon domain NOB1_Zn_bind PF08772.11 CAR21901.1 - 4.6 7.5 9.8 5 7.4 0.3 3.4 3 2 1 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2_4 PF13894.6 CAR21901.1 - 5.5 8.1 10.9 15 6.8 1.0 3.8 4 0 0 4 4 3 0 C2H2-type zinc finger Ribosomal_S27e PF01667.17 CAR21901.1 - 5.5 6.8 9.9 22 4.9 0.0 3.7 2 2 1 3 3 3 0 Ribosomal protein S27 zf-HYPF PF07503.12 CAR21901.1 - 7.2 6.5 12.5 11 5.9 0.2 4.0 4 0 0 4 4 4 0 HypF finger PADR1 PF08063.12 CAR21901.1 - 7.5 6.4 13.6 12 5.8 3.4 3.6 2 2 0 2 2 2 0 PADR1 (NUC008) domain DUF983 PF06170.12 CAR21901.1 - 7.6 7.0 12.0 36 4.9 0.3 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF983) zinc-ribbons_6 PF07191.12 CAR21901.1 - 7.8 6.6 13.4 2.3 8.2 0.9 3.0 3 2 0 3 3 2 0 zinc-ribbons zf-HIT PF04438.16 CAR21901.1 - 7.9 6.5 11.6 23 5.0 0.6 3.9 4 0 0 4 4 4 0 HIT zinc finger zf-NADH-PPase PF09297.11 CAR21901.1 - 8.4 6.2 15.2 14 5.5 0.1 4.2 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain DUF3268 PF11672.8 CAR21901.1 - 9.3 6.6 7.5 0.57 10.5 1.0 2.1 2 1 0 2 2 2 0 zinc-finger-containing domain LicD PF04991.13 CAR21902.1 - 6.6e-47 160.6 2.6 1.7e-46 159.2 2.6 1.7 1 0 0 1 1 1 1 LicD family CN_hydrolase PF00795.22 CAR21903.1 - 2.8e-19 69.5 0.0 7.2e-19 68.1 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase LicD PF04991.13 CAR21904.1 - 3.7e-50 171.2 0.7 3.7e-50 171.2 0.7 2.8 4 0 0 4 4 4 1 LicD family Peptidase_C69 PF03577.15 CAR21904.1 - 0.092 11.7 0.1 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C69 B3 PF02362.21 CAR21904.1 - 0.092 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 B3 DNA binding domain HLH PF00010.26 CAR21905.1 - 4.1e-13 49.1 4.5 9.8e-13 47.9 4.5 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 CAR21906.1 - 3.3e-42 144.7 0.0 4.7e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR21906.1 - 7.4e-21 74.6 0.0 1.3e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR21906.1 - 1e-06 28.3 0.0 3.1e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAR21906.1 - 0.0016 17.8 0.0 0.0046 16.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR21906.1 - 0.0018 18.3 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CAR21906.1 - 0.045 13.4 0.3 1.3 8.6 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CAR21906.1 - 0.068 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family eIF3_p135 PF12807.7 CAR21906.1 - 3 7.8 4.7 1.8 8.5 0.1 2.6 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit 135 AAA PF00004.29 CAR21907.1 - 2.6e-55 186.4 0.0 4.9e-44 150.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CAR21907.1 - 9.2e-25 86.9 0.2 3.2e-24 85.1 0.3 2.0 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CAR21907.1 - 1.2e-13 51.8 0.2 3.2e-06 27.6 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CAR21907.1 - 1.6e-08 34.9 0.8 0.00091 19.5 0.1 3.4 2 2 1 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 CAR21907.1 - 3.5e-08 33.1 0.3 1.5e-06 27.9 0.1 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_14 PF13173.6 CAR21907.1 - 7.8e-08 32.4 0.0 0.008 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CAR21907.1 - 9.5e-08 32.3 0.0 0.0033 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CAR21907.1 - 5.2e-07 29.6 0.0 0.0056 16.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CAR21907.1 - 5.6e-07 30.2 0.0 0.065 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CAR21907.1 - 9.6e-07 28.9 0.4 0.029 14.3 0.0 3.4 3 1 0 3 3 3 2 NACHT domain AAA_33 PF13671.6 CAR21907.1 - 1.2e-05 25.5 0.0 0.016 15.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CAR21907.1 - 2.7e-05 24.2 0.1 0.29 11.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CAR21907.1 - 2.8e-05 24.5 0.1 0.57 10.6 0.0 3.5 3 0 0 3 3 3 2 RNA helicase TsaE PF02367.17 CAR21907.1 - 7.5e-05 22.7 0.1 0.18 11.8 0.0 3.3 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CAR21907.1 - 0.0002 20.9 0.0 0.09 12.3 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RuvB_N PF05496.12 CAR21907.1 - 0.00024 20.9 0.0 0.0032 17.2 0.0 2.5 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR21907.1 - 0.00026 21.3 0.1 0.78 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CAR21907.1 - 0.00033 20.4 0.2 0.25 11.0 0.0 3.0 3 1 0 4 4 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CAR21907.1 - 0.00052 19.4 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CAR21907.1 - 0.00064 19.5 0.0 0.84 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CAR21907.1 - 0.00071 19.6 0.0 0.25 11.2 0.0 3.0 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CAR21907.1 - 0.0012 18.2 0.5 1 8.6 0.0 3.5 4 0 0 4 4 3 1 Zeta toxin AAA_25 PF13481.6 CAR21907.1 - 0.0014 18.2 1.9 0.19 11.3 0.1 3.0 2 2 1 3 3 3 1 AAA domain ATP-synt_ab PF00006.25 CAR21907.1 - 0.0024 17.6 0.0 0.68 9.5 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.27 CAR21907.1 - 0.003 18.1 0.2 2.9 8.4 0.2 3.2 2 1 0 2 2 2 1 ABC transporter AAA_3 PF07726.11 CAR21907.1 - 0.0032 17.3 0.0 0.38 10.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CAR21907.1 - 0.0036 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 CAR21907.1 - 0.0037 16.5 0.2 1.7 7.8 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 CAR21907.1 - 0.0044 16.9 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein NTPase_1 PF03266.15 CAR21907.1 - 0.0049 16.8 1.5 0.62 9.9 0.1 3.3 3 0 0 3 3 3 1 NTPase AAA_29 PF13555.6 CAR21907.1 - 0.0049 16.6 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATPase PF06745.13 CAR21907.1 - 0.0092 15.4 0.0 4 6.7 0.0 2.4 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.22 CAR21907.1 - 0.014 14.6 0.1 3 6.9 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.13 CAR21907.1 - 0.014 14.6 0.1 0.048 12.9 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain KAP_NTPase PF07693.14 CAR21907.1 - 0.014 14.7 0.0 0.087 12.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Viral_helicase1 PF01443.18 CAR21907.1 - 0.015 15.0 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 CAR21907.1 - 0.016 15.6 0.1 0.25 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CAR21907.1 - 0.018 15.0 0.0 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SKI PF01202.22 CAR21907.1 - 0.019 15.1 0.1 0.89 9.7 0.0 2.9 3 0 0 3 3 3 0 Shikimate kinase RsgA_GTPase PF03193.16 CAR21907.1 - 0.024 14.5 0.0 0.087 12.7 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 CAR21907.1 - 0.03 14.7 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 CAR21907.1 - 0.074 12.5 0.2 1.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CbiA PF01656.23 CAR21907.1 - 0.083 13.0 0.1 1 9.4 0.0 2.7 3 1 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 CAR21907.1 - 0.09 12.0 0.0 13 4.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 CAR21907.1 - 0.13 11.8 0.6 6.3 6.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PEX-2N PF09263.10 CAR21907.1 - 0.16 12.3 0.0 0.59 10.5 0.0 1.9 2 0 0 2 2 1 0 Peroxisome biogenesis factor 1, N-terminal APS_kinase PF01583.20 CAR21907.1 - 0.17 11.7 0.1 5.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.6 CAR21907.1 - 0.18 11.5 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 CAR21908.1 - 3e-50 169.8 1.0 3.4e-50 169.7 1.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain WH1 PF00568.23 CAR21908.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 WH1 domain Thymidylate_kin PF02223.17 CAR21909.1 - 7.1e-40 136.7 0.0 8.2e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 CAR21909.1 - 0.026 15.1 0.0 0.042 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4588 PF15251.6 CAR21911.1 - 6.9e-10 39.1 0.1 7.8e-10 38.9 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) FUSC PF04632.12 CAR21911.1 - 0.023 13.3 1.5 0.026 13.1 1.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hairy_orange PF07527.13 CAR21911.1 - 0.15 12.3 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Hairy Orange SUR7 PF06687.12 CAR21912.1 - 7.6e-41 140.1 14.9 9e-41 139.8 14.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family SLATT_5 PF18160.1 CAR21912.1 - 0.11 11.9 2.0 0.54 9.5 0.0 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF996 PF06195.13 CAR21912.1 - 5.7 7.2 11.6 8.5 6.7 7.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF996) GFO_IDH_MocA PF01408.22 CAR21913.1 - 3.4e-05 24.7 0.0 5.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CAR21913.1 - 0.18 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Hit1_C PF18268.1 CAR21914.1 - 1.1e-43 147.2 0.8 1.8e-43 146.6 0.8 1.3 1 0 0 1 1 1 1 Hit1 C-terminal zf-HIT PF04438.16 CAR21914.1 - 2.1e-11 43.5 12.4 2.1e-11 43.5 12.4 1.4 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 CAR21914.1 - 0.011 15.5 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 CAR21914.1 - 0.02 15.0 11.2 0.035 14.2 11.2 1.4 1 0 0 1 1 1 0 MYND finger GerE PF00196.19 CAR21914.1 - 0.082 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family zf-C6H2 PF15801.5 CAR21914.1 - 0.41 11.0 10.7 0.95 9.8 10.7 1.6 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Atg14 PF10186.9 CAR21914.1 - 0.58 9.2 6.0 0.74 8.8 6.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-B_box PF00643.24 CAR21914.1 - 1.6 9.0 12.6 1.4 9.2 10.1 1.9 2 0 0 2 2 2 0 B-box zinc finger Suc_Fer-like PF06999.12 CAR21915.1 - 3.8e-36 124.8 0.0 4.9e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MMS1_N PF10433.9 CAR21916.1 - 4.3e-73 246.6 0.3 7.8e-73 245.8 0.1 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CAR21916.1 - 1.8e-49 168.8 0.0 5.1e-49 167.3 0.0 1.8 1 1 0 1 1 1 1 CPSF A subunit region Evr1_Alr PF04777.13 CAR21916.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 Erv1 / Alr family Gsf2 PF11055.8 CAR21917.1 - 3.6e-174 578.8 0.1 4.1e-174 578.7 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 DUF5398 PF17376.2 CAR21917.1 - 0.061 13.9 0.6 0.21 12.2 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5398) KCH PF16944.5 CAR21918.1 - 2e-94 316.1 19.2 2.5e-94 315.7 19.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel Pox_I1 PF03289.13 CAR21918.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus protein I1 Mad3_BUB1_I PF08311.12 CAR21920.1 - 0.012 15.5 11.8 1.6 8.7 0.1 4.9 4 1 1 5 5 5 0 Mad3/BUB1 homology region 1 OTCace PF00185.24 CAR21920.1 - 0.094 12.8 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Cnd1 PF12717.7 CAR21920.1 - 0.15 12.1 1.1 2.3 8.2 0.1 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 UPF0122 PF04297.14 CAR21920.1 - 0.22 11.8 6.9 2 8.7 0.5 3.1 3 0 0 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like LRR_6 PF13516.6 CAR21921.1 - 0.0056 16.6 0.4 1.1e+02 3.2 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich repeat Alpha_E2_glycop PF00943.19 CAR21921.1 - 0.14 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein DUF3813 PF12758.7 CAR21921.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) LRR_4 PF12799.7 CAR21921.1 - 0.45 11.0 14.5 1.2 9.6 0.0 5.7 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) FAM76 PF16046.5 CAR21921.1 - 0.62 9.4 18.0 1 8.7 18.0 1.4 1 0 0 1 1 1 0 FAM76 protein DUF676 PF05057.14 CAR21922.1 - 3.5e-42 144.4 0.0 5.2e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CAR21922.1 - 0.00021 21.2 0.0 0.00034 20.5 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 CAR21922.1 - 0.0054 16.5 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 CAR21922.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.12 CAR21922.1 - 0.17 11.8 0.1 0.41 10.6 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Sedlin_N PF04628.13 CAR21923.1 - 5e-13 49.3 0.3 5.8e-13 49.1 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RecQ_Zn_bind PF16124.5 CAR21923.1 - 0.0087 16.8 0.0 0.019 15.7 0.0 1.5 1 1 0 1 1 1 1 RecQ zinc-binding DUF2004 PF09406.10 CAR21923.1 - 0.04 14.2 0.1 0.065 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) FAD_binding_2 PF00890.24 CAR21924.1 - 2.9e-71 240.8 0.1 3.3e-71 240.6 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CAR21924.1 - 1.1e-10 41.6 0.4 2.6e-09 37.1 0.4 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR21924.1 - 2.7e-07 30.7 0.1 1.2e-06 28.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CAR21924.1 - 1.5e-05 24.2 0.1 0.092 11.8 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 CAR21924.1 - 3.1e-05 23.4 0.4 0.0047 16.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family IF2_N PF04760.15 CAR21924.1 - 0.00011 22.0 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 2 Translation initiation factor IF-2, N-terminal region FAD_binding_3 PF01494.19 CAR21924.1 - 0.00012 21.4 0.1 0.00058 19.2 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CAR21924.1 - 0.0017 17.2 0.8 0.19 10.4 0.1 3.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_2 PF07992.14 CAR21924.1 - 0.0024 17.2 3.6 0.0036 16.6 1.9 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR21924.1 - 0.038 14.0 0.1 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 CAR21924.1 - 0.068 12.0 0.2 0.42 9.4 0.0 1.9 2 0 0 2 2 2 0 MCRA family FAD_oxidored PF12831.7 CAR21924.1 - 0.099 12.0 0.1 0.27 10.5 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_S15 PF02129.18 CAR21924.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) 14-3-3 PF00244.20 CAR21924.1 - 0.16 11.5 0.2 0.33 10.4 0.0 1.5 2 0 0 2 2 2 0 14-3-3 protein Beta_elim_lyase PF01212.21 CAR21925.1 - 3.9e-77 259.4 0.0 4.7e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase YL1_C PF08265.11 CAR21926.1 - 4.3e-12 45.6 0.9 1.6e-11 43.8 0.1 2.0 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Mac PF12464.8 CAR21927.1 - 8.6e-14 51.5 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 CAR21927.1 - 1.4e-09 37.3 16.7 3.7e-06 26.4 4.6 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CAR21927.1 - 2.8e-05 23.8 13.6 0.00011 21.8 3.2 3.4 3 1 2 5 5 5 3 Hexapeptide repeat of succinyl-transferase fn3 PF00041.21 CAR21928.1 - 0.00059 20.1 0.1 0.0031 17.8 0.1 2.3 1 0 0 1 1 1 1 Fibronectin type III domain fn3_4 PF16794.5 CAR21928.1 - 0.055 13.4 0.1 0.49 10.3 0.1 2.5 2 1 0 2 2 2 0 Fibronectin-III type domain Rpn9_C PF18261.1 CAR21928.1 - 0.12 12.0 4.0 0.29 10.8 4.0 1.6 1 0 0 1 1 1 0 Rpn9 C-terminal helix Phlebovirus_NSM PF07246.11 CAR21928.1 - 0.3 10.4 7.6 0.7 9.2 7.6 1.7 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Acetyltransf_16 PF05301.11 CAR21928.1 - 3.7 7.3 7.6 1.5 8.5 0.7 2.7 3 0 0 3 3 3 0 GNAT acetyltransferase, Mec-17 DUF1640 PF07798.11 CAR21928.1 - 5.3 7.1 15.8 0.017 15.2 4.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) Isy1 PF06246.12 CAR21929.1 - 2.6e-60 204.1 4.2 3e-60 204.0 4.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DivIC PF04977.15 CAR21929.1 - 0.11 12.3 1.2 0.53 10.1 0.3 2.4 2 0 0 2 2 2 0 Septum formation initiator Glyco_hydro_32N PF00251.20 CAR21930.1 - 2.5e-88 296.6 6.7 3.6e-88 296.1 6.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CAR21930.1 - 5.1e-15 55.8 0.1 1.1e-14 54.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal GDA1_CD39 PF01150.17 CAR21931.1 - 2.1e-122 408.8 0.0 2.5e-122 408.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_S49_N PF08496.10 CAR21931.1 - 0.11 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NAD_kinase PF01513.21 CAR21932.1 - 6.2e-80 268.5 0.0 8.7e-80 268.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CAR21932.1 - 0.017 14.7 0.0 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain SMG1_N PF17229.2 CAR21932.1 - 0.38 11.5 2.8 4.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Serine/threonine-protein kinase SMG1 N-terminal Glyco_hydro_16 PF00722.21 CAR21933.1 - 2.4e-45 154.2 7.3 6e-45 152.9 7.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 CAR21933.1 - 0.049 14.1 12.9 0.11 13.0 12.9 1.6 1 0 0 1 1 1 0 Chitin recognition protein Cytochrom_C PF00034.21 CAR21934.1 - 1.8e-10 41.8 0.3 3.1e-10 41.0 0.3 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CAR21934.1 - 2.1e-07 31.2 2.3 2e-06 28.1 2.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CAR21934.1 - 0.17 11.6 1.0 0.74 9.5 0.3 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain HAD_2 PF13419.6 CAR21935.1 - 0.0018 18.4 0.0 0.0025 17.9 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR21935.1 - 0.015 15.6 0.0 0.065 13.5 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nup88 PF10168.9 CAR21935.1 - 0.019 12.8 0.0 0.025 12.4 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore component Hydrolase_like PF13242.6 CAR21935.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like UBA PF00627.31 CAR21936.1 - 1.8e-29 101.2 4.1 2.1e-16 59.4 0.4 2.4 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CAR21936.1 - 2.9e-17 62.2 0.4 9e-17 60.6 0.4 1.8 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 CAR21936.1 - 1.7e-11 43.7 0.6 1.7e-11 43.7 0.6 2.1 2 0 0 2 2 1 1 XPC-binding domain Rad60-SLD PF11976.8 CAR21936.1 - 5.4e-08 32.6 1.4 1.6e-07 31.1 1.4 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CAR21936.1 - 0.00014 21.9 0.0 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CAR21936.1 - 0.0002 21.7 0.5 0.00041 20.7 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CAR21936.1 - 0.0005 20.6 4.5 0.00096 19.7 0.1 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain TFIIA PF03153.13 CAR21936.1 - 0.0022 18.1 21.4 0.0028 17.7 21.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CUE PF02845.16 CAR21936.1 - 0.014 15.1 0.3 0.32 10.8 0.0 3.3 3 1 0 3 3 3 0 CUE domain DUF3306 PF11748.8 CAR21936.1 - 0.02 15.7 4.2 0.02 15.7 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) PAT1 PF09770.9 CAR21936.1 - 0.026 12.8 11.9 0.034 12.4 11.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UBA_3 PF09288.10 CAR21936.1 - 0.028 14.2 0.0 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain ThiS PF02597.20 CAR21936.1 - 0.045 14.4 0.6 0.4 11.4 0.0 2.6 3 0 0 3 3 2 0 ThiS family RAP1 PF07218.11 CAR21936.1 - 0.2 9.9 3.2 0.23 9.7 3.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) V_ATPase_I PF01496.19 CAR21936.1 - 1.2 7.0 4.9 1.7 6.4 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 CAR21936.1 - 3.1 7.3 25.8 0.28 10.8 19.4 2.0 2 0 0 2 2 2 0 Spt20 family CCDC117 PF15810.5 CAR21936.1 - 3.6 7.9 11.9 0.25 11.6 6.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 EIIBC-GUT_N PF03612.14 CAR21936.1 - 3.6 7.3 5.5 15 5.3 5.1 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF5327 PF17261.2 CAR21936.1 - 3.8 8.3 17.9 0.24 12.1 8.8 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5327) DUF3408 PF11888.8 CAR21936.1 - 8.2 6.6 15.2 1.6 8.8 6.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) YjbH PF06082.11 CAR21936.1 - 10 4.8 9.3 13 4.5 9.3 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Anp1 PF03452.14 CAR21937.1 - 2.6e-112 374.6 0.0 3.6e-112 374.1 0.0 1.2 1 0 0 1 1 1 1 Anp1 eIF-5a PF01287.20 CAR21938.1 - 1.8e-30 104.8 0.3 2.6e-30 104.3 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CAR21938.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-BED PF02892.15 CAR21939.1 - 0.00012 22.0 2.4 0.0002 21.3 1.0 2.0 3 0 0 3 3 3 1 BED zinc finger MCM PF00493.23 CAR21940.1 - 7.3e-97 322.9 0.3 1.1e-96 322.2 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR21940.1 - 5.7e-33 113.5 0.0 1.1e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAR21940.1 - 8.8e-24 83.8 1.3 1.9e-23 82.7 1.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAR21940.1 - 1.2e-08 35.5 0.6 1.2e-07 32.2 0.2 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR21940.1 - 6.3e-08 32.2 0.0 1.6e-06 27.6 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAR21940.1 - 0.00027 20.8 0.1 0.0042 16.9 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAR21940.1 - 0.0077 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CAR21940.1 - 0.043 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) E1-E2_ATPase PF00122.20 CAR21941.1 - 4.6e-19 68.6 0.0 8.6e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CAR21941.1 - 2.1e-18 67.4 0.0 6.2e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR21941.1 - 1.1e-08 35.1 0.1 2e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CAR21941.1 - 0.0016 18.2 0.1 0.024 14.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RCC1_2 PF13540.6 CAR21941.1 - 0.1 12.4 0.4 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat CDT1_C PF16679.5 CAR21942.1 - 4.9e-06 26.9 0.1 1.9e-05 25.0 0.1 2.1 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Ku PF02735.16 CAR21943.1 - 7.6e-30 104.1 0.3 1.3e-29 103.3 0.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CAR21943.1 - 7.4e-29 101.1 1.1 1.3e-28 100.2 1.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CAR21943.1 - 1e-05 26.2 2.1 1e-05 26.2 2.1 2.5 2 1 0 2 2 2 1 Ku70/Ku80 C-terminal arm Apis_Csd PF11671.8 CAR21943.1 - 0.014 15.4 0.8 0.87 9.6 0.0 2.9 3 0 0 3 3 3 0 Complementary sex determiner protein Exo_endo_phos PF03372.23 CAR21944.1 - 3.9e-27 95.3 0.0 5.1e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L30 PF00327.20 CAR21945.1 - 3.2e-13 49.3 0.1 5.1e-13 48.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNB PF00773.19 CAR21947.1 - 1.5e-62 211.9 0.0 3.1e-62 210.8 0.0 1.6 1 0 0 1 1 1 1 RNB domain Rit1_C PF17184.4 CAR21948.1 - 6e-94 314.5 0.0 8.6e-94 314.0 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CAR21948.1 - 2.8e-26 92.0 2.3 6.4e-26 90.8 1.0 2.1 2 0 0 2 2 2 1 Rit1 DUSP-like domain DUF3567 PF12091.8 CAR21948.1 - 0.018 15.1 0.0 0.04 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) ATP13 PF12921.7 CAR21949.1 - 1.7e-31 108.5 0.1 1.2e-30 105.8 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial ATPase expression Nyv1_N PF09426.10 CAR21949.1 - 0.08 13.0 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal GIIM PF08388.11 CAR21949.1 - 1.5 8.9 5.3 0.3 11.2 1.0 2.1 2 0 0 2 2 2 0 Group II intron, maturase-specific domain PIG-L PF02585.17 CAR21950.1 - 3.3e-18 66.6 0.1 4.7e-18 66.1 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Fungal_trans PF04082.18 CAR21951.1 - 1.9e-42 145.2 0.7 4.7e-42 143.9 0.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR21951.1 - 2.9e-10 40.1 13.1 5.8e-10 39.1 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nab6_mRNP_bdg PF10567.9 CAR21952.1 - 5e-68 229.9 3.2 3.7e-67 227.1 1.5 2.7 2 1 0 2 2 2 1 RNA-recognition motif RRM PF10378.9 CAR21952.1 - 7.5e-19 67.2 5.9 7.5e-19 67.2 5.9 2.3 2 0 0 2 2 2 1 Putative RRM domain RRM_1 PF00076.22 CAR21952.1 - 8.2e-05 22.4 1.9 0.67 9.8 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CAR21952.1 - 0.017 15.2 0.1 4.4 7.4 0.0 3.0 3 0 0 3 3 3 0 RNA binding motif DUF1987 PF09345.10 CAR21952.1 - 0.039 13.6 0.7 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) MFS_1 PF07690.16 CAR21953.1 - 5.4e-41 140.7 40.5 5.4e-41 140.7 40.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR21953.1 - 9.2e-06 24.8 9.8 9.2e-06 24.8 9.8 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Ost5 PF05251.12 CAR21953.1 - 0.015 15.5 0.8 0.015 15.5 0.8 4.1 4 1 1 5 5 5 0 Oligosaccharyltransferase subunit 5 SLAC1 PF03595.17 CAR21953.1 - 0.39 9.9 42.9 0.6 9.3 10.4 2.4 1 1 1 2 2 2 0 Voltage-dependent anion channel Anp1 PF03452.14 CAR21954.1 - 6.5e-121 402.8 0.0 7.9e-121 402.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 S-methyl_trans PF02574.16 CAR21955.1 - 9.4e-61 206.0 0.0 1.1e-60 205.8 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase PGM_PMM_I PF02878.16 CAR21956.1 - 3.1e-38 130.6 0.0 5.5e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CAR21956.1 - 1.4e-21 77.1 0.0 2.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CAR21956.1 - 2.4e-14 53.5 0.0 5.4e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CAR21956.1 - 5e-07 29.8 0.2 1.8e-06 28.0 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NIF PF03031.18 CAR21957.1 - 2.3e-23 82.7 0.0 7.3e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CAR21957.1 - 5.9e-10 39.4 0.0 1.7e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CAR21957.1 - 0.00043 20.2 0.1 0.00099 19.0 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CAR21957.1 - 0.0015 18.9 0.0 0.0053 17.1 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CAR21957.1 - 0.028 14.7 0.1 0.093 13.0 0.1 1.8 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Biotin_lipoyl_2 PF13533.6 CAR21957.1 - 0.059 13.2 0.0 0.74 9.7 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like TAF8_C PF10406.9 CAR21958.1 - 1.9e-17 63.5 0.8 1.9e-17 63.5 0.8 3.1 2 1 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Nbs1_C PF08599.10 CAR21958.1 - 0.97 9.6 0.0 0.97 9.6 0.0 3.2 4 0 0 4 4 4 0 DNA damage repair protein Nbs1 ubiquitin PF00240.23 CAR21959.1 - 4e-21 74.5 0.1 5.9e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAR21959.1 - 6.2e-10 38.8 0.0 9.6e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 CAR21959.1 - 4.8e-05 23.2 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain UBA PF00627.31 CAR21959.1 - 0.00026 20.8 0.1 0.00056 19.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD_2 PF13881.6 CAR21959.1 - 0.0047 17.0 0.0 0.0097 16.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CAR21959.1 - 0.005 17.4 0.0 0.0086 16.6 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.6 CAR21959.1 - 0.015 15.8 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain HOIP-UBA PF16678.5 CAR21959.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_4 PF18036.1 CAR21959.1 - 0.053 13.6 0.2 2.1 8.4 0.2 2.2 1 1 0 1 1 1 0 Ubiquitin-like domain STI1 PF17830.1 CAR21959.1 - 4.4 7.3 14.0 2.6 8.1 4.9 2.7 1 1 1 2 2 2 0 STI1 domain RBR PF17208.3 CAR21960.1 - 0.028 15.1 2.6 0.028 15.1 2.6 3.2 2 2 1 3 3 3 0 RNA binding Region CTK3_C PF12350.8 CAR21961.1 - 6.7e-15 55.0 1.0 1.4e-14 54.0 1.0 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 CAR21961.1 - 4.8e-05 23.4 1.1 0.00074 19.5 0.4 2.7 1 1 1 2 2 2 1 CTD kinase subunit gamma CTK3 Bul1_N PF04425.12 CAR21962.1 - 4.6e-160 533.3 1.4 4.6e-160 533.3 1.4 2.0 2 1 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 CAR21962.1 - 1.2e-98 329.9 13.2 1.2e-98 329.9 13.2 2.3 3 0 0 3 3 3 1 Bul1 C terminus CPBP PF02517.16 CAR21963.1 - 3.8e-16 59.2 3.5 1.2e-15 57.7 3.5 1.8 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Zds_C PF08632.10 CAR21964.1 - 3e-29 100.5 0.8 4.9e-29 99.8 0.8 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF1892 PF08987.10 CAR21965.1 - 4.8e-52 174.8 1.2 5.3e-52 174.6 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) CDT1 PF08839.11 CAR21965.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.4 2 0 0 2 2 2 0 DNA replication factor CDT1 like Cyt-b5 PF00173.28 CAR21966.1 - 1.5e-19 69.9 0.3 1.5e-19 69.9 0.3 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CAR21966.1 - 7.6e-15 55.4 14.9 7.6e-15 55.4 14.9 2.2 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 CAR21966.1 - 0.028 14.6 0.2 0.055 13.7 0.2 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region ECF_trnsprt PF12822.7 CAR21966.1 - 0.27 11.3 3.0 0.36 10.9 2.4 1.5 1 1 0 1 1 1 0 ECF transporter, substrate-specific component zf-C3HC PF07967.13 CAR21967.1 - 2.4e-11 43.8 0.3 5.2e-07 29.8 0.2 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Pribosyltran PF00156.27 CAR21968.1 - 5.3e-17 61.8 0.1 7.2e-17 61.4 0.1 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain SRP19 PF01922.17 CAR21969.1 - 1e-29 103.3 0.0 1.8e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein RRN9 PF10680.9 CAR21970.1 - 1.4e-15 57.3 1.5 2.1e-15 56.8 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor PXA PF02194.15 CAR21971.1 - 3.9e-34 118.2 2.6 7.1e-34 117.4 0.1 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CAR21971.1 - 1.3e-21 77.3 0.2 4.4e-21 75.6 0.2 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 CAR21971.1 - 6.5e-14 51.9 6.5 6.1e-13 48.8 3.3 2.9 3 0 0 3 3 3 1 PX domain RGS PF00615.19 CAR21971.1 - 3.2e-08 33.9 3.7 2.2e-07 31.2 0.7 3.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain G-patch PF01585.23 CAR21972.1 - 0.012 15.5 0.9 0.086 12.8 0.9 2.4 1 1 0 1 1 1 0 G-patch domain Neur_chan_memb PF02932.16 CAR21972.1 - 0.52 10.3 4.9 0.48 10.4 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.15 CAR21972.1 - 6.2 5.5 15.3 6.8 5.4 15.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 CAR21972.1 - 7.9 6.2 24.2 10 5.8 24.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 CAR21973.1 - 3.1e-37 126.2 0.1 2.9e-10 39.8 0.0 4.6 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR21973.1 - 9.1e-31 105.6 0.0 1.5e-23 82.4 0.0 4.9 5 0 0 5 5 5 2 Occluded RNA-recognition motif Lsm_interact PF05391.11 CAR21973.1 - 2.2e-06 26.9 0.3 6.9e-06 25.4 0.3 1.8 1 0 0 1 1 1 1 Lsm interaction motif RRM_5 PF13893.6 CAR21973.1 - 0.0012 18.5 0.1 2.2 7.9 0.0 3.7 2 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR21973.1 - 0.0035 17.4 0.0 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif DUF1866 PF08952.11 CAR21973.1 - 0.0071 16.2 0.1 0.84 9.5 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF1866) Nup188 PF10487.9 CAR21974.1 - 5.4e-292 971.1 16.4 9.4e-292 970.3 16.4 1.4 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CAR21974.1 - 1.8e-24 86.3 5.1 4e-24 85.1 5.1 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain PAH PF02671.21 CAR21974.1 - 0.041 14.0 0.1 0.18 11.9 0.1 2.2 1 0 0 1 1 1 0 Paired amphipathic helix repeat RAP-1 PF03085.15 CAR21974.1 - 0.11 12.2 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pyrophosphatase PF00719.19 CAR21975.1 - 2.3e-53 180.3 0.0 2.9e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase RSN1_7TM PF02714.15 CAR21976.1 - 2.5e-88 296.0 31.3 2.5e-88 296.0 31.3 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR21976.1 - 1.3e-41 141.9 0.9 1.3e-41 141.9 0.9 3.0 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CAR21976.1 - 5.4e-33 114.7 0.1 8.6e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CAR21976.1 - 1.1e-28 99.3 0.1 2.9e-28 97.9 0.1 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter EloA-BP1 PF15870.5 CAR21976.1 - 0.01 16.1 0.3 0.019 15.3 0.3 1.3 1 0 0 1 1 1 0 ElonginA binding-protein 1 DUF4618 PF15397.6 CAR21976.1 - 0.03 13.7 0.2 0.051 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Peptidase_G2 PF11962.8 CAR21976.1 - 0.04 13.3 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase_G2, IMC autoproteolytic cleavage domain HAD_SAK_1 PF10307.9 CAR21977.1 - 1.2e-63 214.7 0.3 2.3e-63 213.7 0.1 1.6 2 0 0 2 2 2 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins WD40 PF00400.32 CAR21978.1 - 7e-23 80.5 9.8 3.1e-06 27.8 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR21978.1 - 8.5e-16 58.0 0.1 3.9e-08 33.5 0.0 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR21978.1 - 2.1e-05 24.5 0.1 0.0045 16.9 0.0 3.1 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 CAR21978.1 - 0.00012 21.3 0.0 0.014 14.5 0.0 2.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40_like PF17005.5 CAR21978.1 - 0.0031 16.9 0.8 0.053 12.8 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 CAR21978.1 - 0.0086 14.8 0.1 0.015 14.0 0.1 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 HPS3_N PF14761.6 CAR21978.1 - 0.013 15.1 0.0 0.25 10.8 0.0 2.5 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 CAR21978.1 - 0.13 11.2 0.8 16 4.3 0.0 3.2 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CAR21978.1 - 0.14 12.2 0.0 7.2 6.7 0.0 2.7 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 CAR21978.1 - 0.19 11.7 0.5 4 7.5 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cue1_U7BR PF18499.1 CAR21979.1 - 2.2e-24 85.3 1.0 3.9e-24 84.4 1.0 1.5 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 CUE PF02845.16 CAR21979.1 - 4.7e-09 35.8 0.1 9.2e-09 34.8 0.1 1.5 1 0 0 1 1 1 1 CUE domain Bse634I PF07832.11 CAR21980.1 - 0.032 13.6 0.1 1.3 8.3 0.0 2.1 1 1 0 2 2 2 0 Cfr10I/Bse634I restriction endonuclease SAP30_Sin3_bdg PF13867.6 CAR21981.1 - 4.5e-12 46.1 0.1 3e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 TatD_DNase PF01026.21 CAR21982.1 - 2.3e-39 135.3 0.0 2.8e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Glyco_transf_20 PF00982.21 CAR21983.1 - 4.9e-164 546.5 0.0 1.5e-163 544.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CAR21983.1 - 1.9e-32 112.3 0.0 8.7e-32 110.1 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase eIF-1a PF01176.19 CAR21984.1 - 4.6e-20 71.2 0.1 6.3e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Mg_trans_NIPA PF05653.14 CAR21985.1 - 6.3e-107 357.1 16.9 7.7e-107 356.8 16.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CAR21985.1 - 0.00011 22.4 6.4 0.00011 22.4 6.4 3.4 3 1 0 3 3 3 1 EamA-like transporter family SMP_2 PF10144.9 CAR21985.1 - 0.00082 19.1 0.8 0.53 9.9 0.0 2.4 1 1 1 2 2 2 2 Bacterial virulence factor haemolysin Acyl_transf_3 PF01757.22 CAR21985.1 - 0.046 12.8 12.7 0.42 9.6 1.0 2.2 1 1 1 2 2 2 0 Acyltransferase family DUF4131 PF13567.6 CAR21985.1 - 0.21 11.2 3.5 3.3 7.3 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.15 CAR21985.1 - 5.9 7.4 17.7 4.5 7.8 0.0 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF202) DUF2428 PF10350.9 CAR21986.1 - 1e-46 159.4 0.1 2.4e-46 158.2 0.1 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CAR21986.1 - 5.3e-06 26.2 3.8 1.4 9.4 0.0 6.8 8 1 1 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 CAR21986.1 - 6.5e-05 23.2 0.1 0.22 11.9 0.0 4.1 3 1 2 5 5 5 2 HEAT repeats DUF1262 PF06880.11 CAR21987.1 - 0.048 14.1 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1262) zf-C3HC4_4 PF15227.6 CAR21989.1 - 8.5e-08 32.2 4.3 8.5e-08 32.2 4.3 2.4 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CAR21989.1 - 3.9e-07 30.3 2.8 3.9e-07 30.3 2.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CAR21989.1 - 4.7e-07 29.7 0.3 1.4e-06 28.2 0.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR21989.1 - 8.7e-07 28.7 3.8 8.7e-07 28.7 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR21989.1 - 1.1e-06 28.5 1.9 1.1e-06 28.5 1.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CAR21989.1 - 1.1e-05 25.2 2.3 1.1e-05 25.2 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR21989.1 - 1.5e-05 24.8 1.8 1.5e-05 24.8 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAR21989.1 - 3.5e-05 24.0 2.3 3.5e-05 24.0 2.3 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR21989.1 - 0.00075 19.5 3.3 0.0019 18.2 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CAR21989.1 - 0.00097 19.0 10.6 0.0011 18.8 2.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 DZR PF12773.7 CAR21989.1 - 0.0012 18.9 9.0 0.25 11.4 0.4 2.5 2 1 0 2 2 2 2 Double zinc ribbon HypA PF01155.19 CAR21989.1 - 0.0017 18.4 4.8 0.086 12.9 0.1 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 CAR21989.1 - 0.0056 16.2 1.3 0.0056 16.2 1.3 2.2 2 0 0 2 2 2 1 RecR protein zinc_ribbon_9 PF14369.6 CAR21989.1 - 0.0084 16.3 2.9 0.0084 16.3 2.9 3.0 2 1 0 2 2 2 1 zinc-ribbon zf-RING_4 PF14570.6 CAR21989.1 - 0.03 14.1 2.6 0.03 14.1 2.6 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 CAR21989.1 - 0.12 12.3 5.5 18 5.3 0.7 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CAR21989.1 - 0.22 11.5 6.2 5.8 7.0 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbons DUF678 PF05077.12 CAR21989.1 - 1.4 9.1 5.3 38 4.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF678) zf-TFIIB PF13453.6 CAR21989.1 - 2.6 7.4 6.2 17 4.8 0.5 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-RING_6 PF14835.6 CAR21989.1 - 3.5 7.6 8.8 16 5.5 2.8 2.6 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_7 PF02591.15 CAR21989.1 - 5.3 7.3 6.6 58 4.0 0.1 3.3 3 0 0 3 3 3 0 C4-type zinc ribbon domain COX7a PF02238.15 CAR21990.1 - 3.5e-24 84.9 0.4 3.9e-24 84.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII SLC3A2_N PF16028.5 CAR21990.1 - 0.072 12.7 0.2 0.078 12.5 0.2 1.1 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus GFD1 PF17331.2 CAR21992.1 - 1.5e-08 34.6 10.4 3.7e-08 33.3 10.4 1.7 1 0 0 1 1 1 1 GFD1 mRNA transport factor EamA PF00892.20 CAR21993.1 - 1e-27 97.0 26.9 3e-16 59.8 2.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CAR21993.1 - 2.2e-06 26.8 1.0 3.6e-06 26.2 0.9 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like DUF2070 PF09843.9 CAR21993.1 - 0.0042 15.4 12.1 0.075 11.3 4.9 2.1 1 1 1 2 2 2 2 Predicted membrane protein (DUF2070) DUF2417 PF10329.9 CAR21993.1 - 1.1 8.6 5.8 2.9 7.2 5.8 1.7 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Amidase PF01425.21 CAR21995.1 - 1.4e-85 287.9 0.0 1.8e-85 287.6 0.0 1.1 1 0 0 1 1 1 1 Amidase UQ_con PF00179.26 CAR21996.1 - 2e-43 147.4 0.0 2.6e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR21996.1 - 0.019 14.7 0.0 0.053 13.2 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Nop14 PF04147.12 CAR21996.1 - 0.6 8.2 15.1 0.66 8.1 15.1 1.2 1 0 0 1 1 1 0 Nop14-like family SLM4 PF16818.5 CAR21997.1 - 4.8e-61 205.4 0.4 6.2e-61 205.1 0.4 1.1 1 0 0 1 1 1 1 Protein SLM4 Dfp1_Him1_M PF08630.10 CAR21998.1 - 7.8e-41 139.2 0.0 2.2e-40 137.8 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 CAR21998.1 - 1.8e-18 66.3 4.9 3.8e-18 65.3 4.9 1.5 1 0 0 1 1 1 1 DBF zinc finger CtIP_N PF10482.9 CAR21998.1 - 0.03 14.3 0.7 0.1 12.6 0.7 1.9 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain YozD PF14162.6 CAR21998.1 - 0.53 10.6 1.5 0.57 10.5 0.1 1.8 2 0 0 2 2 2 0 YozD-like protein zf-C2H2 PF00096.26 CAR21999.1 - 8.3e-10 38.6 10.0 0.00012 22.3 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR21999.1 - 3.8e-05 23.9 0.3 3.8e-05 23.9 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 CAR21999.1 - 0.00093 18.8 2.9 0.0018 17.8 2.9 1.5 1 0 0 1 1 1 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 CAR21999.1 - 0.037 14.4 7.1 1.4 9.4 1.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 CAR21999.1 - 0.059 13.3 1.7 0.16 11.9 1.7 1.7 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_4 PF13894.6 CAR21999.1 - 0.09 13.7 13.1 0.83 10.7 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CAR21999.1 - 0.79 10.1 6.0 1 9.7 1.8 3.1 3 1 0 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CAR21999.1 - 1.3 9.3 6.2 7.9 6.9 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Glyco_hydro81C PF17652.1 CAR22000.1 - 1.7e-146 487.9 7.4 2.4e-146 487.5 7.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CAR22000.1 - 7.8e-98 327.6 3.8 7.8e-98 327.6 3.8 2.5 2 1 1 3 3 3 1 Glycosyl hydrolase family 81 N-terminal domain TPR_2 PF07719.17 CAR22002.1 - 6.3e-11 41.5 2.6 0.096 12.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAR22002.1 - 2.9e-06 27.0 3.1 1.2 9.5 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR22002.1 - 3.9e-06 26.5 0.8 1.9 8.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR22002.1 - 4.4e-06 26.9 11.8 1.1 9.6 0.1 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.10 CAR22002.1 - 0.00048 19.2 0.5 0.11 11.5 0.1 2.8 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) LigB PF02900.18 CAR22002.1 - 0.00055 19.1 0.1 0.011 14.9 0.2 2.2 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase TPR_17 PF13431.6 CAR22002.1 - 0.00082 19.6 0.0 0.14 12.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR22002.1 - 0.018 15.6 3.2 20 5.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAR22002.1 - 0.12 12.1 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.6 CAR22002.1 - 0.13 13.1 9.4 4.8 8.3 0.1 6.0 5 2 2 7 7 7 0 Tetratricopeptide repeat Peptidase_M28 PF04389.17 CAR22003.1 - 7.3e-36 123.7 0.0 2.8e-35 121.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 CAR22003.1 - 0.00072 19.3 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CAR22003.1 - 0.0011 18.1 0.0 0.0054 15.8 0.0 1.9 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase DPM3 PF08285.11 CAR22003.1 - 0.25 11.6 4.0 0.12 12.5 0.3 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) URO-D PF01208.17 CAR22004.1 - 3.8e-125 417.6 0.0 4.3e-125 417.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PSP PF04046.16 CAR22004.1 - 0.12 12.3 0.7 0.25 11.2 0.1 1.8 2 0 0 2 2 2 0 PSP bVLRF1 PF18826.1 CAR22005.1 - 5e-60 201.7 0.4 1.2e-59 200.5 0.4 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 CAR22005.1 - 4.4e-06 26.9 0.1 1.5e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR22005.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF1431 PF07248.12 CAR22005.1 - 0.024 14.9 1.1 0.059 13.6 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1431) FdhD-NarQ PF02634.15 CAR22005.1 - 0.21 11.3 1.6 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 FdhD/NarQ family SNF2_N PF00176.23 CAR22006.1 - 2.8e-57 194.0 0.1 4.4e-57 193.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR22006.1 - 2.5e-16 60.0 0.0 2.4e-15 56.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR22006.1 - 1.4e-12 47.9 0.0 1.6e-10 41.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR22006.1 - 3.7e-06 26.8 0.1 7.7e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CAR22006.1 - 4.4e-06 26.1 0.0 1.1e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2439 PF10382.9 CAR22006.1 - 0.039 14.3 0.1 0.093 13.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) RhoGEF67_u2 PF16614.5 CAR22007.1 - 0.05 13.7 0.4 0.08 13.0 0.4 1.3 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 Alg14 PF08660.11 CAR22008.1 - 4.3e-54 183.1 0.0 5.3e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TIM PF00121.18 CAR22009.1 - 1.7e-90 302.7 0.2 1.9e-90 302.5 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.22 CAR22010.1 - 3.8e-25 88.7 0.0 5.2e-15 55.7 0.0 3.2 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Thioredoxin PF00085.20 CAR22011.1 - 0.025 14.6 0.0 0.033 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin CX PF01705.19 CAR22011.1 - 0.034 14.7 0.0 0.064 13.8 0.0 1.4 1 0 0 1 1 1 0 CX module AA_permease PF00324.21 CAR22012.1 - 1.3e-125 419.7 41.2 1.6e-125 419.5 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR22012.1 - 5e-37 127.7 34.0 5e-37 127.7 34.0 1.3 1 1 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 CAR22012.1 - 0.051 12.4 1.0 0.091 11.6 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) tRNA-synt_2 PF00152.20 CAR22013.1 - 7.7e-75 251.9 0.2 1e-74 251.5 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR22013.1 - 3.9e-12 46.0 0.1 8.1e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAR22013.1 - 2.2e-07 30.6 0.2 0.0032 17.0 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) FtsJ PF01728.19 CAR22014.1 - 3.2e-69 232.6 0.0 4e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ribosomal_S10 PF00338.22 CAR22015.1 - 7.4e-32 109.5 0.0 4.7e-31 106.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.6 CAR22016.1 - 2.8e-09 37.2 11.9 2.8e-09 37.2 11.9 1.5 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CAR22016.1 - 1.3e-06 28.6 10.6 3.7e-06 27.1 10.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR22016.1 - 0.00064 19.7 5.2 0.0011 19.0 5.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CAR22016.1 - 0.0042 17.1 7.1 0.0042 17.1 7.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR22016.1 - 0.0067 16.2 11.6 0.0067 16.2 11.6 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR22016.1 - 0.0078 16.1 10.7 0.0078 16.1 10.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR22016.1 - 0.09 12.8 8.7 0.17 11.9 8.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAR22016.1 - 0.096 12.6 9.8 0.24 11.3 9.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR22016.1 - 0.12 12.1 8.6 0.3 10.9 8.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 CAR22016.1 - 0.32 11.2 7.3 1.7 8.9 7.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Borealin PF10512.9 CAR22017.1 - 0.025 14.5 0.0 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 FYVE PF01363.21 CAR22017.1 - 2.5 8.3 13.8 0.61 10.3 9.7 2.1 1 1 0 1 1 1 0 FYVE zinc finger Actin PF00022.19 CAR22018.1 - 1.5e-52 178.7 0.0 1.8e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Actin NuA4 PF09340.10 CAR22019.1 - 1.5e-20 72.8 0.4 2.1e-20 72.4 0.4 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Bap31_Bap29_C PF18035.1 CAR22019.1 - 0.00075 19.5 2.6 0.0015 18.5 2.6 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Sds3 PF08598.11 CAR22019.1 - 0.027 14.5 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Sds3-like Prp19 PF08606.11 CAR22019.1 - 2.3 8.3 5.7 14 5.8 0.4 2.2 1 1 1 2 2 2 0 Prp19/Pso4-like AIM24 PF01987.17 CAR22020.1 - 1.5e-32 113.0 0.0 2.1e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 tRNA-synt_His PF13393.6 CAR22021.1 - 6.4e-40 137.3 0.0 4e-39 134.7 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CAR22021.1 - 1e-12 48.0 0.0 2.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CAR22021.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs IDO PF01231.18 CAR22022.1 - 1.5e-149 498.5 0.0 1.8e-149 498.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cid2 PF09774.9 CAR22023.1 - 1.8e-36 126.0 1.6 2.2e-36 125.7 1.6 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Lgl_C PF08596.10 CAR22024.1 - 2.7e-129 431.3 0.1 4.6e-129 430.5 0.1 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CAR22024.1 - 9.5e-11 41.9 0.0 0.0079 16.5 0.0 6.4 6 1 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR22024.1 - 1.1e-06 29.2 0.7 0.54 11.2 0.0 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat WD40_like PF17005.5 CAR22024.1 - 0.0021 17.5 0.1 0.17 11.1 0.0 2.6 2 0 0 2 2 2 2 WD40-like domain Pkinase PF00069.25 CAR22025.1 - 2.6e-59 200.8 2.3 2.7e-59 200.7 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22025.1 - 2.3e-35 122.1 0.0 5e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CAR22025.1 - 9.3e-24 83.3 24.3 6.9e-13 48.5 9.3 2.8 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 CAR22025.1 - 7.2e-19 67.4 36.2 9.5e-11 41.4 16.7 2.6 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CAR22025.1 - 1.1e-11 45.2 1.0 1.1e-11 45.2 1.0 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 CAR22025.1 - 1.3e-06 28.7 0.1 2.9e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 CAR22025.1 - 0.0019 17.6 0.0 0.0019 17.6 0.0 2.7 4 1 0 4 4 4 1 Kinase-like Pkinase_fungal PF17667.1 CAR22025.1 - 0.0024 16.7 0.1 0.0024 16.7 0.1 2.2 2 1 0 2 2 2 1 Fungal protein kinase Uds1 PF15456.6 CAR22025.1 - 0.005 17.0 2.3 0.005 17.0 2.3 3.5 3 0 0 3 3 3 1 Up-regulated During Septation zf-RING_9 PF13901.6 CAR22025.1 - 1.6 8.7 33.1 0.92 9.4 6.4 3.4 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon zinc_ribbon_16 PF17034.5 CAR22026.1 - 1.2e-27 96.5 5.2 4.4e-27 94.8 5.2 2.0 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CAR22026.1 - 3.4e-05 23.4 8.5 0.00011 21.8 8.5 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CAR22026.1 - 0.0071 17.2 0.2 1.8 9.6 0.1 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-HC5HC2H_2 PF13832.6 CAR22027.1 - 1.2e-28 99.4 8.7 1.2e-28 99.4 8.7 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CAR22027.1 - 1.6e-26 92.4 6.7 1.6e-26 92.4 6.7 3.3 2 1 1 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.9 CAR22027.1 - 1.5e-14 54.6 3.0 3.8e-14 53.4 3.0 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.6 CAR22027.1 - 4.9e-14 51.6 3.6 4.9e-14 51.6 3.6 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CAR22027.1 - 1e-09 38.1 7.7 1e-09 38.1 7.7 2.7 2 0 0 2 2 2 1 PHD-finger GED PF02212.18 CAR22027.1 - 1.6 8.9 5.8 6.5 7.0 2.5 2.8 2 1 1 3 3 3 0 Dynamin GTPase effector domain HLH PF00010.26 CAR22028.1 - 3.9e-12 45.9 1.1 7e-12 45.1 1.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GerD PF17898.1 CAR22028.1 - 0.065 13.2 0.1 0.25 11.3 0.1 2.0 1 0 0 1 1 1 0 Spore germination GerD central core domain Got1 PF04178.12 CAR22029.1 - 1.9e-32 112.0 14.6 3e-32 111.4 14.6 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.16 CAR22029.1 - 2.4e-06 26.7 3.4 2.7e-06 26.6 3.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Arrestin_C PF02752.22 CAR22030.1 - 3.5e-13 50.2 0.2 1.4e-12 48.2 0.2 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Adaptin_N PF01602.20 CAR22031.1 - 1.3e-111 373.8 11.4 1.6e-111 373.5 11.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CAR22031.1 - 1.5e-09 38.1 0.0 3.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CAR22031.1 - 0.0015 18.6 5.0 0.056 13.5 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Telomere_reg-2 PF10193.9 CAR22031.1 - 0.5 10.8 6.9 9.3 6.7 0.2 4.4 4 1 0 4 4 4 0 Telomere length regulation protein TB2_DP1_HVA22 PF03134.19 CAR22032.1 - 1.2e-26 92.4 7.1 1.8e-26 91.9 7.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Glyco_hydro_65m PF03632.15 CAR22033.1 - 3.7e-39 134.7 0.3 5.7e-36 124.2 0.0 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CAR22033.1 - 8.1e-17 61.6 0.0 1.9e-16 60.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CAR22033.1 - 0.00096 19.0 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Triabin PF03973.13 CAR22033.1 - 0.15 11.9 0.1 0.32 10.9 0.1 1.5 1 0 0 1 1 1 0 Triabin ATP-synt_ab PF00006.25 CAR22034.1 - 9e-73 244.4 0.0 1.5e-72 243.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CAR22034.1 - 5.8e-47 159.2 0.6 1e-46 158.3 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CAR22034.1 - 1.6e-16 60.6 2.4 4.3e-16 59.2 2.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Cyclin_C_2 PF16899.5 CAR22035.1 - 5.5e-30 103.8 0.1 1.3e-29 102.6 0.0 1.7 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CAR22035.1 - 7.9e-09 35.3 0.2 1.7e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 CAR22035.1 - 0.0047 17.0 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat MPP6 PF10175.9 CAR22035.1 - 0.087 13.3 0.2 0.19 12.3 0.2 1.6 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Peptidase_M41 PF01434.18 CAR22036.1 - 1.1e-59 201.5 0.2 2.1e-59 200.6 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAR22036.1 - 5.9e-41 140.0 0.0 2e-40 138.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR22036.1 - 1.9e-07 30.8 0.0 4.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CAR22036.1 - 1.8e-05 25.2 0.2 0.00012 22.6 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR22036.1 - 0.00032 21.0 0.0 0.13 12.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 CAR22036.1 - 0.00037 19.8 0.0 0.00076 18.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CAR22036.1 - 0.0019 18.0 0.0 0.0083 15.9 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAR22036.1 - 0.0034 17.4 0.1 0.015 15.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CAR22036.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 CAR22036.1 - 0.033 14.3 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CAR22036.1 - 0.059 12.8 0.3 0.12 11.7 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CAR22036.1 - 0.065 12.8 0.9 1.1 8.8 0.4 2.4 1 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CAR22036.1 - 0.086 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CAR22036.1 - 0.092 12.1 0.3 0.56 9.5 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 CAR22036.1 - 0.11 12.5 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAR22036.1 - 0.17 12.4 0.5 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cnd2 PF05786.14 CAR22037.1 - 1.3e-141 473.8 29.6 5.5e-140 468.5 29.6 2.1 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CAR22037.1 - 0.00052 20.2 1.7 0.0031 17.7 0.0 2.9 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FAD_binding_3 PF01494.19 CAR22038.1 - 5.7e-19 68.6 0.0 9.7e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CAR22038.1 - 1.1e-06 28.7 0.1 2.7e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CAR22038.1 - 1.4e-06 28.2 0.0 5.3e-06 26.2 0.1 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CAR22038.1 - 6.3e-06 25.5 0.0 8.5e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CAR22038.1 - 4.9e-05 23.8 0.0 0.00014 22.3 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CAR22038.1 - 0.00013 21.3 0.0 0.00039 19.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CAR22038.1 - 0.00021 21.3 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CAR22038.1 - 0.00039 20.1 0.2 0.001 18.8 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.24 CAR22038.1 - 0.0017 17.5 0.2 0.0027 16.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 CAR22038.1 - 0.0017 17.4 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase UDPG_MGDP_dh_N PF03721.14 CAR22038.1 - 0.0028 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 CAR22038.1 - 0.0037 16.0 0.1 0.0073 15.0 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CAR22038.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 CAR22038.1 - 0.089 11.6 0.1 5.6 5.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 CAR22038.1 - 0.13 11.6 0.7 0.21 10.9 0.7 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Mfa_like_1 PF13149.6 CAR22038.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Fimbrillin-like Glu_dehyd_C PF16912.5 CAR22038.1 - 0.17 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Sugar_tr PF00083.24 CAR22039.1 - 2e-84 284.1 28.3 2.5e-84 283.8 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR22039.1 - 1.5e-11 43.9 48.8 1.3e-09 37.5 50.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily 4HBT PF03061.22 CAR22040.1 - 4.4e-06 27.0 0.0 7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily ArfGap PF01412.18 CAR22041.1 - 3e-34 117.6 0.3 5.9e-34 116.7 0.3 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf A2L_zn_ribbon PF08792.10 CAR22041.1 - 0.084 12.6 1.2 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain DZR PF12773.7 CAR22041.1 - 0.14 12.2 1.0 0.26 11.3 1.0 1.4 1 0 0 1 1 1 0 Double zinc ribbon GATA PF00320.27 CAR22041.1 - 0.18 11.5 0.3 0.3 10.7 0.3 1.4 1 0 0 1 1 1 0 GATA zinc finger Rox3 PF08633.10 CAR22042.1 - 3.3e-39 135.3 0.5 3.9e-39 135.1 0.5 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit DUF1704 PF08014.11 CAR22042.1 - 0.017 14.1 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Glyco_hydro_cc PF11790.8 CAR22042.1 - 0.032 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core RIIa PF02197.17 CAR22042.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Ribosomal_L32e PF01655.18 CAR22044.1 - 3.1e-47 159.5 1.9 3.6e-47 159.3 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Motile_Sperm PF00635.26 CAR22045.1 - 1.2e-25 89.5 0.0 2.4e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CAR22045.1 - 5.9e-05 23.2 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 131-like Big_2 PF02368.18 CAR22045.1 - 0.013 15.4 3.0 0.093 12.6 0.4 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) DUF4693 PF15764.5 CAR22045.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4693) CBP_BcsO PF17037.5 CAR22045.1 - 0.13 12.4 6.5 0.25 11.5 6.5 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO Peptidase_M24 PF00557.24 CAR22046.1 - 2.4e-49 167.9 0.0 2.9e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S21 PF01165.20 CAR22047.1 - 3.9e-10 39.3 2.2 7.9e-10 38.3 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Aa_trans PF01490.18 CAR22048.1 - 3.2e-107 358.8 21.1 3.9e-107 358.5 21.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_1 PF00018.28 CAR22049.1 - 3.8e-10 39.2 0.1 7e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR22049.1 - 5.7e-09 35.7 0.1 9.7e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR22049.1 - 3.2e-06 26.7 0.1 7.8e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_4 PF06347.13 CAR22049.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_10 PF17902.1 CAR22049.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain TctB PF07331.11 CAR22049.1 - 0.84 9.9 8.4 1.4 9.2 8.4 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DHHC PF01529.20 CAR22049.1 - 1.1 9.4 3.2 1.9 8.6 3.2 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase PI3_PI4_kinase PF00454.27 CAR22050.1 - 2.7e-54 184.6 0.0 6.5e-54 183.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CAR22050.1 - 2.3e-25 89.5 0.1 9.6e-25 87.5 0.1 2.2 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 CAR22050.1 - 3.3e-12 46.0 0.0 9.7e-12 44.5 0.0 1.9 1 0 0 1 1 1 1 FATC domain Ribosomal_L14 PF00238.19 CAR22051.1 - 7.8e-33 113.1 0.0 9.3e-33 112.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-C3HC4 PF00097.25 CAR22052.1 - 3.5e-10 39.6 5.9 5.1e-10 39.0 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR22052.1 - 9.6e-10 38.2 4.6 1.4e-09 37.7 4.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR22052.1 - 9.7e-10 38.3 5.0 1.7e-09 37.6 5.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CAR22052.1 - 9.9e-08 32.2 7.1 1.5e-07 31.6 7.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CAR22052.1 - 2.3e-07 30.6 6.6 3.8e-07 29.9 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CAR22052.1 - 2.6e-07 30.4 6.9 6.1e-07 29.2 7.0 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR22052.1 - 5.5e-06 26.1 6.8 1.9e-05 24.4 7.1 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CAR22052.1 - 0.00017 21.6 7.5 0.00028 21.0 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CAR22052.1 - 0.0024 17.9 2.6 0.0037 17.3 2.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CAR22052.1 - 0.094 13.0 4.4 0.2 12.0 4.4 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rtf2 PF04641.12 CAR22052.1 - 0.11 11.8 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_4 PF14570.6 CAR22052.1 - 0.18 11.6 6.5 1.6 8.6 7.0 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 CAR22052.1 - 0.27 11.0 6.0 0.07 12.9 2.2 2.0 2 1 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 CAR22052.1 - 0.75 10.0 5.4 0.34 11.1 2.8 1.7 2 0 0 2 2 2 0 FYVE zinc finger DUF5472 PF17566.2 CAR22053.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5472) NT-C2 PF10358.9 CAR22054.1 - 1.2e-50 171.0 3.1 3.2e-50 169.7 3.1 1.6 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins PH PF00169.29 CAR22056.1 - 4.1e-19 69.0 0.8 4.3e-18 65.8 0.0 2.6 3 0 0 3 3 3 1 PH domain SH3_1 PF00018.28 CAR22056.1 - 1.7e-12 46.7 0.2 3.5e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 CAR22056.1 - 2.7e-10 40.2 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CAR22056.1 - 1.6e-08 34.3 0.2 3.6e-08 33.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 CAR22056.1 - 0.00056 20.3 0.0 0.0052 17.2 0.0 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 CAR22056.1 - 0.00097 19.4 0.0 0.04 14.2 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.17 CAR22056.1 - 0.044 13.5 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain BORCS8 PF10167.9 CAR22056.1 - 0.049 13.6 0.5 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 TPR_1 PF00515.28 CAR22057.1 - 9.6e-37 123.3 16.8 3.3e-08 33.0 0.2 9.7 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 CAR22057.1 - 1.2e-36 121.8 14.1 5.5e-07 29.2 0.1 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR22057.1 - 3.7e-31 107.2 23.3 3.9e-20 71.9 1.7 4.3 5 0 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAR22057.1 - 7.7e-30 100.6 9.4 0.0058 16.7 0.0 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.6 CAR22057.1 - 5.4e-24 83.6 5.9 2e-05 24.2 0.1 8.4 7 2 2 9 9 8 6 TPR repeat TPR_12 PF13424.6 CAR22057.1 - 3.5e-18 65.6 13.4 0.00014 22.1 0.0 8.3 7 2 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAR22057.1 - 2.6e-16 60.0 5.1 1e-05 26.1 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR22057.1 - 2.7e-15 55.6 7.0 0.0044 17.3 0.3 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR22057.1 - 1.3e-12 47.4 4.3 0.61 11.0 0.0 8.9 7 2 3 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAR22057.1 - 9.7e-12 45.2 11.8 0.00011 22.6 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAR22057.1 - 2.4e-09 37.2 3.2 5.5e-05 23.2 0.1 5.5 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR22057.1 - 1.6e-07 30.9 7.3 46 4.4 0.0 8.8 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_15 PF13429.6 CAR22057.1 - 2.3e-07 30.3 0.1 0.035 13.3 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR22057.1 - 2.7e-05 24.5 19.7 0.42 11.4 0.0 9.1 11 0 0 11 11 10 2 Tetratricopeptide repeat DUF2225 PF09986.9 CAR22057.1 - 0.00044 20.0 3.0 0.11 12.2 0.8 3.3 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 CAR22057.1 - 0.0025 18.3 4.1 5.6 7.9 0.0 5.6 8 0 0 8 8 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 CAR22057.1 - 0.0034 17.5 1.8 5.1 7.2 0.1 4.7 3 1 1 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 CAR22057.1 - 0.0096 16.2 0.1 2.1 8.8 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 CAR22057.1 - 0.02 13.9 0.0 0.6 9.1 0.0 2.1 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.6 CAR22057.1 - 0.049 14.1 0.1 0.15 12.5 0.1 1.7 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation SRP_TPR_like PF17004.5 CAR22057.1 - 0.08 13.0 0.1 1.8 8.6 0.0 3.0 2 1 0 2 2 2 0 Putative TPR-like repeat Fis1_TPR_C PF14853.6 CAR22057.1 - 0.099 12.7 3.4 32 4.7 0.0 4.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CAR22057.1 - 0.24 11.8 3.1 14 6.1 0.0 3.2 2 2 1 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 CAR22057.1 - 0.37 10.7 8.6 22 5.1 0.0 5.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR22057.1 - 1.4 8.2 5.9 20 4.4 0.2 4.0 3 2 1 4 4 4 0 MalT-like TPR region EMP70 PF02990.16 CAR22058.1 - 6.7e-117 391.3 16.6 3e-116 389.2 16.6 1.9 1 1 0 1 1 1 1 Endomembrane protein 70 LSM PF01423.22 CAR22059.1 - 1e-18 66.8 0.7 1.8e-18 66.0 0.7 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR22059.1 - 0.0059 16.7 0.0 0.0086 16.2 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF737 PF05300.11 CAR22059.1 - 0.091 13.1 0.0 0.098 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Ank_4 PF13637.6 CAR22060.1 - 5.3e-08 33.3 4.5 0.0045 17.5 0.8 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR22060.1 - 5.7e-06 26.8 2.4 0.0032 18.0 0.6 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR22060.1 - 6.6e-05 23.1 3.0 0.049 14.0 0.5 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 CAR22060.1 - 0.00013 21.8 1.5 0.00013 21.8 1.5 2.8 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.6 CAR22060.1 - 0.0084 16.6 2.0 14 6.6 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CAR22060.1 - 0.32 11.5 3.1 3.3 8.3 0.1 3.3 3 0 0 3 3 3 0 Ankyrin repeat HEAT_EZ PF13513.6 CAR22061.1 - 5.5e-19 68.3 5.7 2.7e-05 24.5 0.0 7.3 8 0 0 8 8 8 4 HEAT-like repeat IBN_N PF03810.19 CAR22061.1 - 1.3e-13 50.7 1.5 2.6e-10 40.1 0.0 3.6 3 0 0 3 3 3 2 Importin-beta N-terminal domain HEAT PF02985.22 CAR22061.1 - 5e-12 45.0 5.7 0.087 13.1 0.0 7.0 7 0 0 7 7 6 3 HEAT repeat HEAT_2 PF13646.6 CAR22061.1 - 1.9e-10 41.0 3.8 0.19 12.1 0.0 6.8 7 1 0 7 7 7 3 HEAT repeats Vac14_Fab1_bd PF12755.7 CAR22061.1 - 6.9e-05 23.4 1.7 0.45 11.1 0.0 5.5 3 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 CAR22061.1 - 0.00014 21.6 0.1 0.71 9.6 0.0 4.9 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 CAR22061.1 - 0.00069 19.5 0.3 0.075 12.9 0.0 3.7 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Cnd1 PF12717.7 CAR22061.1 - 0.0084 16.2 6.4 0.91 9.6 0.1 5.4 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 CAR22061.1 - 0.024 14.8 3.2 65 3.6 0.1 4.8 2 2 3 5 5 5 0 Parkin co-regulated protein DUF3385 PF11865.8 CAR22061.1 - 0.031 14.2 3.3 15 5.5 0.0 5.3 7 1 1 8 8 8 0 Domain of unknown function (DUF3385) HEAT_PBS PF03130.16 CAR22061.1 - 0.042 14.5 1.4 15 6.6 0.1 5.0 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat ALG3 PF05208.13 CAR22062.1 - 2.4e-131 438.4 25.8 2.8e-131 438.2 25.8 1.0 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.11 CAR22063.1 - 1.1e-06 28.3 0.5 2.2e-06 27.4 0.5 1.5 1 0 0 1 1 1 1 LisH WD40 PF00400.32 CAR22064.1 - 2.5e-18 66.1 4.4 0.0001 23.0 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22064.1 - 5.5e-08 33.0 0.0 0.00078 19.7 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR22064.1 - 0.0014 17.4 0.1 0.41 9.2 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CAR22064.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain DUF5349 PF17298.2 CAR22065.1 - 1.7e-125 419.6 43.5 1.9e-125 419.4 43.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5349) TFIIA PF03153.13 CAR22065.1 - 0.0025 17.9 10.2 0.0028 17.7 10.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GatB_N PF02934.15 CAR22066.1 - 1.3e-89 300.2 0.0 1.6e-89 299.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CAR22066.1 - 3.5e-29 101.6 0.1 5.3e-29 101.0 0.1 1.3 1 0 0 1 1 1 1 GatB domain DUF642 PF04862.12 CAR22067.1 - 0.055 13.3 1.0 0.061 13.1 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF642) MAM1 PF10434.9 CAR22068.1 - 2.1e-72 243.9 2.0 2.6e-72 243.7 2.0 1.1 1 0 0 1 1 1 1 Monopolin complex protein MAM1 Nucleoporin_N PF08801.11 CAR22069.1 - 2.3e-133 445.2 7.9 3.8e-133 444.4 7.9 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CAR22069.1 - 1.5e-125 420.3 7.6 1.5e-125 420.3 7.6 2.3 2 1 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF5376 PF17346.2 CAR22069.1 - 0.017 15.5 1.1 1.9 8.8 0.9 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5376) Atg8 PF02991.16 CAR22070.1 - 1.2e-50 170.0 0.1 1.4e-50 169.8 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CAR22070.1 - 2.3e-08 34.3 0.0 3e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.22 CAR22072.1 - 8.9e-231 767.3 0.8 3.3e-230 765.4 0.2 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CAR22072.1 - 7.5e-27 94.2 0.0 2.2e-26 92.6 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CAR22072.1 - 1.4e-15 57.0 1.2 1.2e-05 24.2 0.1 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CAR22072.1 - 5.1e-05 22.8 0.0 0.00057 19.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain HSP70 PF00012.20 CAR22073.1 - 2.3e-258 858.3 7.8 2.6e-258 858.2 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR22073.1 - 3.4e-16 59.0 0.2 3.1e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CAR22073.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CAR22073.1 - 0.079 11.9 0.4 0.59 9.1 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain SWI-SNF_Ssr4 PF08549.10 CAR22073.1 - 3 6.4 5.5 0.99 8.0 0.1 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) AAR2 PF05282.11 CAR22074.1 - 8.1e-32 111.0 0.0 1.2e-31 110.5 0.0 1.2 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S8e PF01201.22 CAR22075.1 - 1.4e-57 193.7 1.8 1.6e-57 193.5 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.13 CAR22076.1 - 4.1e-21 74.5 0.7 6.1e-21 73.9 0.7 1.3 1 0 0 1 1 1 1 CSL zinc finger ATPase-cat_bd PF12156.8 CAR22076.1 - 0.027 15.2 0.2 0.14 12.9 0.1 2.0 2 0 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase ADH_zinc_N_2 PF13602.6 CAR22077.1 - 1.2e-14 55.5 0.0 3.3e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR22077.1 - 2.6e-05 24.0 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR22077.1 - 0.01 15.8 0.0 1.9 8.5 0.0 2.6 1 1 1 2 2 2 0 Zinc-binding dehydrogenase UQ_con PF00179.26 CAR22078.1 - 1.3e-23 83.2 0.1 2.4e-23 82.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR22078.1 - 0.0044 16.7 0.0 0.0091 15.7 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B KorB PF08535.10 CAR22078.1 - 0.096 12.7 0.3 0.16 12.0 0.3 1.4 1 0 0 1 1 1 0 KorB domain EF-G-binding_N PF07299.11 CAR22078.1 - 0.12 13.0 1.6 0.35 11.4 1.6 1.8 1 1 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Wbp11 PF09429.10 CAR22078.1 - 8.4 6.9 9.7 0.72 10.3 1.7 2.4 3 0 0 3 3 3 0 WW domain binding protein 11 Pribosyltran_N PF13793.6 CAR22079.1 - 2e-46 156.7 0.4 8.4e-44 148.2 0.0 2.5 2 1 1 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CAR22079.1 - 3.7e-37 128.1 0.8 5.4e-31 108.0 0.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CAR22079.1 - 2.6e-13 49.8 0.6 6.4e-13 48.5 0.4 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF2007 PF09413.10 CAR22079.1 - 0.08 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein UCH PF00443.29 CAR22080.1 - 5.6e-60 203.0 0.6 8.3e-60 202.4 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR22080.1 - 3.8e-20 72.7 4.6 1.5e-15 57.6 0.6 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.18 CAR22081.1 - 3.2e-18 65.7 2.0 6.6e-18 64.7 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22081.1 - 4.7e-09 36.2 10.3 7.7e-09 35.5 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAS20 PF02064.15 CAR22081.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.2 3 0 0 3 3 3 0 MAS20 protein import receptor AhpC-TSA PF00578.21 CAR22082.1 - 1.7e-32 112.0 0.0 2.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CAR22082.1 - 2.4e-13 49.7 0.5 4.4e-13 48.8 0.5 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CAR22082.1 - 1.1e-10 41.4 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Sel1 PF08238.12 CAR22083.1 - 3e-48 161.2 16.6 3.6e-07 30.6 0.2 7.6 7 0 0 7 7 7 7 Sel1 repeat Rad51 PF08423.11 CAR22084.1 - 8.8e-129 428.2 0.0 1.1e-128 427.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CAR22084.1 - 8.6e-12 45.1 0.0 1.2e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CAR22084.1 - 4.4e-10 39.4 0.0 7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CAR22084.1 - 2.2e-08 34.6 0.2 4.2e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CAR22084.1 - 7.2e-06 25.5 0.1 1.6e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CAR22084.1 - 0.0025 17.2 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 CAR22084.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CAR22084.1 - 0.16 12.2 0.0 0.4 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 CAR22084.1 - 0.27 10.4 0.6 0.52 9.4 0.1 1.6 2 0 0 2 2 2 0 PAXNEB protein Sec7 PF01369.20 CAR22085.1 - 2.2e-16 60.1 0.8 6e-16 58.7 0.2 2.0 2 0 0 2 2 2 1 Sec7 domain Proteasome PF00227.26 CAR22086.1 - 3.7e-40 137.4 0.0 4.5e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.10 CAR22087.1 - 6.7e-16 58.1 9.5 1.7e-15 56.8 9.1 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4413 PF14372.6 CAR22087.1 - 0.0026 18.1 0.2 0.0031 17.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) CBM_14 PF01607.24 CAR22087.1 - 0.012 15.8 0.3 0.016 15.3 0.3 1.3 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain HBS1_N PF08938.10 CAR22087.1 - 0.015 15.6 1.9 0.065 13.6 1.9 2.1 1 1 0 1 1 1 0 HBS1 N-terminus NDUF_B7 PF05676.13 CAR22087.1 - 0.047 13.4 2.5 0.078 12.7 2.5 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) USP19_linker PF16602.5 CAR22087.1 - 0.06 13.9 0.4 0.067 13.7 0.4 1.2 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase MFS_2 PF13347.6 CAR22088.1 - 0.019 13.5 0.1 0.024 13.2 0.1 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein RICTOR_N PF14664.6 CAR22089.1 - 2.5e-87 293.3 0.3 5.3e-87 292.2 0.3 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CAR22089.1 - 5.5e-32 109.6 0.6 2.6e-30 104.3 0.1 4.0 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 CAR22089.1 - 3.3e-31 107.3 0.3 5.7e-28 97.0 0.1 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 CAR22089.1 - 2.1e-29 102.1 0.6 2.9e-28 98.4 0.0 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 CAR22089.1 - 0.014 15.4 0.5 0.52 10.4 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GlnE PF03710.15 CAR22089.1 - 0.061 12.7 0.2 0.19 11.1 0.2 1.8 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase LANC_like PF05147.13 CAR22089.1 - 0.15 10.6 0.2 0.47 9.0 0.0 1.8 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein HEAT PF02985.22 CAR22089.1 - 0.41 11.0 1.6 31 5.2 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat UPF0449 PF15136.6 CAR22089.1 - 0.87 10.1 5.4 3.8 8.0 4.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 IES5 PF17335.2 CAR22090.1 - 2.3e-31 108.4 6.3 2.5e-31 108.3 6.3 1.0 1 0 0 1 1 1 1 Ino80 complex subunit 5 Caudo_TAP PF02413.17 CAR22090.1 - 0.00049 20.2 1.0 0.0006 20.0 1.0 1.2 1 0 0 1 1 1 1 Caudovirales tail fibre assembly protein, lambda gpK V_ATPase_I PF01496.19 CAR22090.1 - 0.018 13.0 0.9 0.02 12.9 0.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA28_beta PF02252.18 CAR22090.1 - 0.045 13.4 0.4 0.17 11.6 0.3 1.9 1 1 1 2 2 2 0 Proteasome activator pa28 beta subunit PilO PF04350.13 CAR22090.1 - 0.086 13.0 2.5 0.12 12.5 2.5 1.2 1 0 0 1 1 1 0 Pilus assembly protein, PilO NYD-SP28_assoc PF14775.6 CAR22090.1 - 0.18 12.0 2.9 2 8.6 1.2 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain Radial_spoke PF04712.12 CAR22091.1 - 0.083 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Meth_synt_2 PF01717.18 CAR22092.1 - 3.9e-152 506.1 0.0 9.2e-148 491.8 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CAR22092.1 - 1.2e-125 419.2 0.0 7.1e-118 393.7 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 CAR22092.1 - 0.11 11.6 0.0 1.4 8.0 0.0 2.5 3 0 0 3 3 3 0 Uroporphyrinogen decarboxylase (URO-D) Corona_RPol_N PF06478.13 CAR22092.1 - 0.17 10.9 0.1 15 4.5 0.0 2.2 2 0 0 2 2 2 0 Coronavirus RPol N-terminus SEP PF08059.13 CAR22093.1 - 1.6e-23 83.1 0.3 1.6e-23 83.1 0.3 1.9 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 CAR22093.1 - 2.6e-13 50.0 0.0 4.7e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CAR22093.1 - 0.0024 17.6 1.4 0.0064 16.3 1.4 1.8 1 1 0 1 1 1 1 UBA-like domain PTH2 PF01981.16 CAR22094.1 - 1.4e-44 151.1 0.1 2.9e-44 150.1 0.0 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DUF4611 PF15387.6 CAR22094.1 - 0.0072 16.5 2.3 0.013 15.7 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) tRNA-synt_1_2 PF13603.6 CAR22094.1 - 0.047 13.2 0.0 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 HTH_ParB PF17762.1 CAR22094.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 HTH domain found in ParB protein Chorismate_bind PF00425.18 CAR22095.1 - 5.4e-91 304.7 0.0 9.7e-91 303.9 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CAR22095.1 - 7.9e-31 107.2 0.0 1.1e-28 100.2 0.0 3.1 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Serendipity_A PF05482.12 CAR22095.1 - 0.041 12.5 0.0 0.074 11.7 0.0 1.4 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) DUF2730 PF10805.8 CAR22095.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PP2C PF00481.21 CAR22097.1 - 3.1e-79 266.2 0.0 4.4e-79 265.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C TatD_DNase PF01026.21 CAR22098.1 - 4.1e-39 134.5 0.0 6.1e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Auts2 PF15336.6 CAR22098.1 - 0.2 11.7 0.9 13 5.8 1.5 2.2 1 1 0 2 2 2 0 Autism susceptibility gene 2 protein zf-C2H2 PF00096.26 CAR22099.1 - 1.8e-05 24.9 15.7 0.00044 20.6 1.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR22099.1 - 0.0004 20.7 2.6 0.0004 20.7 2.6 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR22099.1 - 0.021 15.6 13.1 1.4 10.0 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Coprogen_oxidas PF01218.18 CAR22100.1 - 7.5e-136 451.6 0.0 8.5e-136 451.5 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.18 CAR22101.1 - 4.7e-22 77.6 1.7 4.7e-22 77.6 1.7 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CAR22101.1 - 1.1e-11 44.4 0.5 1.7e-10 40.6 0.1 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CAR22101.1 - 6.2e-05 22.9 4.8 0.075 13.0 0.5 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain C1_1 PF00130.22 CAR22101.1 - 0.0089 15.9 2.1 0.034 14.0 0.4 2.2 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Desulfoferrod_N PF06397.12 CAR22101.1 - 0.31 10.7 3.2 0.45 10.2 0.1 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Zn_ribbon_SprT PF17283.2 CAR22101.1 - 0.33 10.9 9.0 3.1 7.8 0.1 3.2 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Lar_restr_allev PF14354.6 CAR22101.1 - 0.37 11.2 7.3 0.57 10.6 0.7 2.4 1 1 2 3 3 3 0 Restriction alleviation protein Lar zf-RING_7 PF02591.15 CAR22101.1 - 1.1 9.5 8.0 1.3 9.3 0.0 3.8 4 1 0 4 4 4 0 C4-type zinc ribbon domain zinc_ribbon_4 PF13717.6 CAR22101.1 - 1.5 8.8 7.6 11 6.0 1.1 3.6 3 1 0 3 3 3 0 zinc-ribbon domain Ogr_Delta PF04606.12 CAR22101.1 - 2.4 8.2 6.3 16 5.6 0.1 2.9 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.10 CAR22101.1 - 5.1 7.3 9.8 23 5.2 0.0 3.9 3 1 0 4 4 4 0 Zinc ribbon domain Auto_anti-p27 PF06677.12 CAR22101.1 - 7.4 6.8 7.9 0.73 10.0 0.5 2.6 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ORC2 PF04084.14 CAR22102.1 - 4.6e-117 390.6 0.1 5.5e-117 390.4 0.1 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FtsK_SpoIIIE PF01580.18 CAR22102.1 - 0.18 11.2 0.0 0.58 9.5 0.0 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family ORC6 PF05460.13 CAR22102.1 - 0.48 9.6 11.9 0.87 8.8 11.9 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.25 CAR22103.1 - 3.4e-37 128.3 0.0 3.4e-37 128.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22103.1 - 2.3e-25 89.4 0.0 2.3e-25 89.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CAR22103.1 - 0.069 13.1 12.8 1.2 9.1 0.0 3.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family FA_desaturase PF00487.24 CAR22104.1 - 5.5e-21 75.6 16.9 5.8e-21 75.5 15.8 1.5 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 CAR22104.1 - 3.5e-18 64.8 1.7 8.6e-18 63.5 1.7 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) ECH_2 PF16113.5 CAR22105.1 - 2.4e-88 296.9 0.0 3.1e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CAR22105.1 - 5.7e-26 91.3 0.1 1.3e-24 86.9 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase UCH PF00443.29 CAR22106.1 - 1.3e-38 133.0 0.0 3.5e-38 131.6 0.0 1.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CAR22106.1 - 1.2e-21 76.8 4.5 1.2e-21 76.8 4.5 3.1 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CAR22106.1 - 4e-17 62.8 7.4 5.2e-16 59.1 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CAR22106.1 - 1.2e-12 47.5 1.1 7.3e-09 35.4 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 CAR22106.1 - 3.4e-11 42.7 7.4 1.1e-10 41.1 1.7 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger Zn_Tnp_IS91 PF14319.6 CAR22106.1 - 0.036 14.1 5.7 9.9 6.3 0.1 4.2 4 0 0 4 4 4 0 Transposase zinc-binding domain Wtap PF17098.5 CAR22107.1 - 6.8e-07 29.4 13.6 1.3e-06 28.5 13.6 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family SlyX PF04102.12 CAR22107.1 - 2.2 9.0 14.6 12 6.6 4.3 3.5 3 1 0 3 3 3 0 SlyX DAHP_synth_1 PF00793.20 CAR22108.1 - 1.4e-104 348.8 0.0 1.6e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cellulase PF00150.18 CAR22109.1 - 2.5e-09 37.0 4.6 3.6e-09 36.5 4.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PRP1_N PF06424.12 CAR22110.1 - 5.2e-39 134.0 0.2 1.3e-38 132.7 0.2 1.7 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 CAR22110.1 - 3.4e-19 69.1 7.8 0.0052 17.3 0.0 7.1 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAR22110.1 - 3.2e-18 64.8 15.3 0.0031 18.2 0.0 11.7 10 3 4 14 14 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAR22110.1 - 8.7e-12 44.2 13.9 0.065 13.4 0.0 10.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAR22110.1 - 1e-09 38.9 6.6 0.54 10.9 0.1 7.5 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR22110.1 - 3.3e-07 30.0 6.6 11 6.5 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_15 PF13429.6 CAR22110.1 - 5.1e-07 29.2 13.9 0.00026 20.3 0.8 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR22110.1 - 1.8e-06 28.2 6.1 3.5 8.0 0.0 7.4 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR22110.1 - 6.4e-06 25.8 3.0 0.77 9.5 0.0 6.4 8 0 0 8 8 8 1 TPR repeat TPR_1 PF00515.28 CAR22110.1 - 0.00018 21.2 13.9 2.4 8.1 0.0 7.0 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR22110.1 - 0.00036 20.7 2.6 0.089 13.2 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR22110.1 - 0.0017 18.9 1.9 13 6.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAR22110.1 - 0.0042 17.2 1.9 5 7.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 CAR22110.1 - 0.046 14.4 6.5 0.072 13.8 0.1 3.5 3 0 0 3 3 3 0 Sel1 repeat ANAPC3 PF12895.7 CAR22110.1 - 0.13 12.5 6.9 6.3 7.1 0.1 4.6 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 CAR22110.1 - 0.18 11.8 9.3 14 5.7 0.0 4.8 5 0 0 5 5 4 0 Mad3/BUB1 homology region 1 Fungal_trans_2 PF11951.8 CAR22111.1 - 3.6e-22 78.7 0.2 5.3e-22 78.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22111.1 - 2.4e-07 30.7 12.5 4.8e-07 29.8 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.21 CAR22112.1 - 2.6e-87 292.9 0.1 3.3e-87 292.6 0.1 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CAR22112.1 - 0.093 13.0 0.2 0.15 12.3 0.2 1.3 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.18 CAR22113.1 - 1.3e-59 200.5 27.7 8e-39 132.9 7.3 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CAR22113.1 - 1.4e-07 31.6 3.5 1.4e-07 31.6 3.5 4.0 3 3 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain SGL PF08450.12 CAR22114.1 - 3.9e-58 196.9 0.0 5.2e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CAR22114.1 - 0.038 14.2 0.0 0.12 12.6 0.0 1.8 1 0 0 1 1 1 0 Arylesterase Str_synth PF03088.16 CAR22114.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase FMN_red PF03358.15 CAR22115.1 - 6e-09 35.8 0.0 7.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CAR22115.1 - 0.0006 19.6 0.0 0.0008 19.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CAR22115.1 - 0.0053 17.0 0.5 0.099 12.8 0.5 2.4 1 1 0 1 1 1 1 Flavodoxin CX9C PF16860.5 CAR22116.1 - 1.1e-27 95.7 15.1 1.6e-19 69.6 3.8 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CAR22116.1 - 2e-08 34.1 10.6 0.00022 21.3 1.4 2.2 2 0 0 2 2 2 2 CHCH domain UPF0203 PF05254.12 CAR22116.1 - 8.4e-06 26.0 8.6 0.0045 17.2 1.2 3.1 1 1 1 3 3 3 2 Uncharacterised protein family (UPF0203) COX6B PF02297.17 CAR22116.1 - 0.00017 21.8 8.1 0.0044 17.2 5.8 2.1 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 CAR22116.1 - 0.0005 20.0 11.1 0.0039 17.2 2.8 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 CAR22116.1 - 0.0051 17.0 9.6 0.026 14.7 1.8 2.6 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein NDUF_B7 PF05676.13 CAR22116.1 - 0.0077 15.9 6.4 0.042 13.6 0.5 3.0 1 1 2 3 3 3 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 CAR22116.1 - 0.044 14.1 13.6 0.19 12.1 8.3 3.0 1 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 GCK PF07802.11 CAR22116.1 - 0.074 13.5 8.4 2 8.9 2.1 2.5 1 1 2 3 3 3 0 GCK domain DB PF01682.19 CAR22116.1 - 0.079 13.3 10.3 0.38 11.1 10.0 2.0 1 1 0 1 1 1 0 DB module WD40 PF00400.32 CAR22117.1 - 1.4e-18 66.9 13.9 0.00024 21.8 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22117.1 - 5.5e-08 33.0 0.0 1.1 9.6 0.0 5.1 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR22117.1 - 7.7e-05 21.5 0.4 0.0018 17.0 0.0 3.0 2 1 1 4 4 4 1 Nucleoporin Nup120/160 DUF2415 PF10313.9 CAR22117.1 - 0.033 14.1 0.1 15 5.6 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF1752 PF08550.10 CAR22118.1 - 1.2e-13 50.6 2.4 4e-13 48.9 2.4 2.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Vps54_N PF10475.9 CAR22119.1 - 3.1e-05 23.4 5.0 5e-05 22.7 5.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Prominin PF05478.11 CAR22119.1 - 0.0065 14.5 3.5 0.011 13.8 3.5 1.3 1 0 0 1 1 1 1 Prominin YlbD_coat PF14071.6 CAR22119.1 - 0.049 13.9 3.6 1 9.6 0.8 3.0 3 0 0 3 3 3 0 Putative coat protein Vps54 PF07928.12 CAR22119.1 - 0.053 14.0 0.2 0.45 11.0 0.0 2.4 2 0 0 2 2 2 0 Vps54-like protein Spectrin_like PF18373.1 CAR22119.1 - 2.7 8.1 5.9 11 6.1 0.6 3.9 3 1 1 4 4 4 0 Spectrin like domain DUF1963 PF09234.10 CAR22120.1 - 1.2e-64 218.7 1.2 1.4e-64 218.4 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) DUF1963 PF09234.10 CAR22121.1 - 6.4e-69 232.7 1.1 7.6e-69 232.4 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) Myb_DNA-binding PF00249.31 CAR22124.1 - 8.8e-24 83.4 19.2 8.4e-13 48.3 0.6 5.0 4 1 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR22124.1 - 5.8e-19 68.1 14.8 9.3e-16 57.8 2.0 3.7 3 1 1 4 4 4 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CAR22124.1 - 0.13 12.5 0.3 0.72 10.1 0.1 2.3 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 CAR22124.1 - 0.19 12.1 11.8 1.7 9.0 0.2 4.0 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CAR22124.1 - 0.74 10.2 15.3 0.66 10.4 7.0 3.7 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Med15 PF09606.10 CAR22124.1 - 8.4 4.9 31.2 0.077 11.7 22.3 1.9 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_S17_N PF16205.5 CAR22125.1 - 2.4e-33 114.3 1.3 4.3e-33 113.5 1.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CAR22125.1 - 2.1e-27 95.0 3.6 2.1e-27 95.0 3.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 FMP23 PF17315.2 CAR22126.1 - 2.5e-73 245.2 0.1 2.9e-73 245.0 0.1 1.0 1 0 0 1 1 1 1 Found in mitochondrial proteome ADH_zinc_N PF00107.26 CAR22127.1 - 1.1e-25 90.1 0.0 1.9e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR22127.1 - 4.2e-19 69.9 0.0 8.5e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR22127.1 - 1e-07 31.8 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 CAR22127.1 - 0.0079 15.7 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase tRNA-synt_2b PF00587.25 CAR22129.1 - 4.4e-32 111.5 0.0 8.1e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CAR22129.1 - 2.7e-22 79.0 10.3 2.7e-22 79.0 10.3 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain HDV_ag PF01517.18 CAR22129.1 - 0.041 13.7 2.2 0.076 12.8 2.2 1.4 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen CCDC71L PF15374.6 CAR22129.1 - 0.063 12.5 3.5 0.11 11.8 3.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L GED PF02212.18 CAR22129.1 - 0.19 11.9 1.7 0.39 10.9 1.7 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain Atg31 PF09795.9 CAR22130.1 - 3.2e-27 95.4 2.5 1.2e-26 93.6 2.5 1.7 1 1 0 1 1 1 1 Autophagy-related protein 31 DEAD PF00270.29 CAR22131.1 - 3.8e-43 147.3 1.9 6.9e-43 146.4 1.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR22131.1 - 2.7e-34 117.9 0.3 1.9e-32 111.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CAR22131.1 - 6.1e-05 22.8 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CAR22131.1 - 0.00012 22.1 0.1 0.00027 21.0 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAR22131.1 - 0.00024 21.4 0.4 0.0014 19.0 0.3 2.0 2 0 0 2 2 2 1 AAA domain tRNA-synt_1b PF00579.25 CAR22131.1 - 0.03 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.14 CAR22131.1 - 0.034 14.0 0.0 0.08 12.8 0.0 1.7 1 1 0 1 1 1 0 Helicase PhoH PF02562.16 CAR22131.1 - 0.038 13.5 2.2 0.19 11.2 2.2 2.1 1 1 0 1 1 1 0 PhoH-like protein CMS1 PF14617.6 CAR22131.1 - 0.041 13.2 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CobA_CobO_BtuR PF02572.15 CAR22131.1 - 0.076 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TniB PF05621.11 CAR22131.1 - 0.084 12.3 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial TniB protein UvrD-helicase PF00580.21 CAR22131.1 - 0.14 11.6 0.2 0.19 11.2 0.2 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 CAR22131.1 - 0.16 12.2 2.1 0.79 10.0 1.6 2.3 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 CAR22132.1 - 4.7e-10 39.5 0.0 6.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF5632 PF18646.1 CAR22133.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5632) GCV_T PF01571.21 CAR22134.1 - 5.6e-85 284.8 0.1 7.2e-85 284.5 0.1 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CAR22134.1 - 5.9e-14 51.7 0.1 1.7e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CAR22134.1 - 0.00024 21.3 0.0 0.021 15.0 0.0 2.3 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family AA_permease PF00324.21 CAR22135.1 - 6.4e-109 364.7 36.7 7.3e-109 364.5 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR22135.1 - 2.9e-42 145.0 37.2 3.5e-42 144.7 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease Rad54_N PF08658.10 CAR22135.1 - 0.17 12.1 0.1 0.26 11.4 0.1 1.2 1 0 0 1 1 1 0 Rad54 N terminal MgtE PF01769.16 CAR22135.1 - 7.8 6.9 27.9 0.37 11.2 5.7 5.2 2 2 1 3 3 3 0 Divalent cation transporter MFS_1 PF07690.16 CAR22136.1 - 2e-37 128.9 22.8 2e-37 128.9 22.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CAR22136.1 - 0.018 13.4 0.7 0.087 11.1 0.6 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family V_ATPase_I PF01496.19 CAR22136.1 - 0.042 11.8 0.0 0.063 11.2 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PsbI PF02532.14 CAR22136.1 - 0.062 13.2 1.2 0.17 11.8 0.7 2.0 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Acyltransferase PF01553.21 CAR22137.1 - 4.9e-29 100.7 0.0 8.6e-29 99.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CAR22137.1 - 1.4e-15 57.1 0.0 3.7e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus AMP-binding PF00501.28 CAR22138.1 - 4.3e-60 203.5 0.0 5.4e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR22138.1 - 0.00022 22.2 0.0 0.00054 20.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl_transf_3 PF01757.22 CAR22138.1 - 0.68 8.9 6.2 0.72 8.9 0.8 2.2 2 0 0 2 2 2 0 Acyltransferase family Fig1 PF12351.8 CAR22139.1 - 8.1e-61 205.2 5.3 8.1e-61 205.2 5.3 1.4 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 CAR22139.1 - 0.012 15.2 13.3 0.018 14.7 13.3 1.2 1 0 0 1 1 1 0 SUR7/PalI family TcpE PF12648.7 CAR22139.1 - 9.5 6.8 7.9 1.1 9.9 2.3 2.2 2 0 0 2 2 2 0 TcpE family ATP-synt PF00231.19 CAR22140.1 - 2.9e-77 260.2 3.1 3.2e-77 260.0 3.1 1.0 1 0 0 1 1 1 1 ATP synthase IPK PF03770.16 CAR22141.1 - 4.9e-51 173.4 0.0 1.2e-50 172.2 0.0 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase DASH_Dad1 PF08649.10 CAR22142.1 - 9e-26 89.8 1.1 1.2e-25 89.5 1.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 PNP_phzG_C PF10590.9 CAR22144.1 - 9.2e-19 67.3 1.2 9.2e-19 67.3 1.2 1.8 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CAR22144.1 - 9.4e-16 57.8 0.0 1.4e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Wap1 PF16997.5 CAR22145.1 - 4.4e-119 398.0 10.7 6e-119 397.6 10.7 1.1 1 0 0 1 1 1 1 Wap1 domain WAPL PF07814.13 CAR22145.1 - 0.0085 14.9 0.5 0.02 13.7 0.1 1.8 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Sld5 PF05916.11 CAR22146.1 - 6.5e-10 39.5 0.7 9.8e-10 38.9 0.7 1.3 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.14 CAR22146.1 - 0.03 13.5 0.2 0.047 12.9 0.0 1.4 2 0 0 2 2 2 0 PIF1-like helicase Mitoc_mL59 PF18126.1 CAR22147.1 - 8.6e-29 100.5 2.6 8.6e-29 100.5 2.6 2.0 1 1 1 2 2 2 1 Mitochondrial ribosomal protein mL59 Spore_YhaL PF14147.6 CAR22147.1 - 1.8 8.3 4.7 3 7.6 4.7 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL PRP38 PF03371.15 CAR22148.1 - 1.9e-47 161.3 0.5 2.4e-47 161.0 0.5 1.0 1 0 0 1 1 1 1 PRP38 family LSM PF01423.22 CAR22149.1 - 1.3e-22 79.3 0.2 1.9e-22 78.7 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR22149.1 - 0.00018 21.6 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Ribosomal_L1 PF00687.21 CAR22149.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L1p/L10e family Smg4_UPF3 PF03467.15 CAR22151.1 - 4.8e-32 111.4 40.3 5.8e-29 101.3 40.3 3.6 1 1 0 1 1 1 1 Smg-4/UPF3 family PCI PF01399.27 CAR22152.1 - 3.2e-09 37.2 0.9 2.2e-08 34.5 0.0 2.7 3 1 0 3 3 3 1 PCI domain Orexin PF02072.15 CAR22152.1 - 0.21 11.5 0.2 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Prepro-orexin DUF2777 PF10949.8 CAR22152.1 - 1.1 8.9 4.6 4.2 7.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2777) Metallophos PF00149.28 CAR22153.1 - 7.7e-38 131.0 0.1 1e-37 130.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR22153.1 - 0.00044 20.6 0.2 0.0011 19.4 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CAR22153.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain E1_DerP2_DerF2 PF02221.15 CAR22154.1 - 1.6e-31 109.5 0.1 1.8e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 ML domain Y_Y_Y PF07495.13 CAR22154.1 - 0.14 12.2 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Y_Y_Y domain Sdh5 PF03937.16 CAR22155.1 - 1.7e-26 92.0 0.7 2.7e-26 91.3 0.7 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase CHCH PF06747.13 CAR22156.1 - 3.8e-06 26.9 0.4 5.3e-06 26.4 0.4 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CAR22156.1 - 0.02 14.9 0.9 0.031 14.3 0.9 1.3 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAPS_reduct PF01507.19 CAR22157.1 - 1.7e-30 106.4 0.0 2.4e-29 102.6 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF445 PF04286.12 CAR22158.1 - 0.042 13.7 2.9 0.1 12.4 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF2200 PF09966.9 CAR22158.1 - 0.22 11.7 2.0 1.1 9.4 0.4 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF573 PF04504.14 CAR22158.1 - 1.2 9.8 0.0 1.2 9.8 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function, DUF573 MAJIN PF15077.6 CAR22159.1 - 5.1 6.8 11.2 0.7 9.6 0.1 2.5 1 1 0 2 2 2 0 Membrane-anchored junction protein FMO-like PF00743.19 CAR22160.1 - 4.3e-12 45.2 1.2 1.9e-05 23.3 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CAR22160.1 - 1.3e-05 24.6 0.0 0.0081 15.4 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR22160.1 - 2.2e-05 24.5 0.1 0.0016 18.5 0.0 3.3 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CAR22160.1 - 0.00013 22.1 0.0 0.00053 20.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CAR22160.1 - 0.00019 20.8 0.0 0.0034 16.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR22160.1 - 0.033 12.9 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 CAR22160.1 - 0.15 11.1 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Nuf2 PF03800.14 CAR22161.1 - 7e-43 146.1 0.3 7e-43 146.1 0.3 2.7 2 1 0 2 2 2 1 Nuf2 family DUF1599 PF07659.11 CAR22161.1 - 0.069 13.6 0.6 0.51 10.8 0.1 2.7 2 0 0 2 2 2 0 Nucleotide modification associated domain 1 DUF600 PF04634.12 CAR22161.1 - 0.45 10.5 9.1 1.1 9.3 0.7 3.3 2 1 1 3 3 3 0 Protein of unknown function, DUF600 Allexi_40kDa PF05549.11 CAR22161.1 - 0.96 8.9 16.1 0.16 11.5 3.6 2.6 1 1 0 2 2 2 0 Allexivirus 40kDa protein XhlA PF10779.9 CAR22161.1 - 1.9 8.7 14.5 5.3 7.3 0.3 4.4 4 1 1 5 5 5 0 Haemolysin XhlA SlyX PF04102.12 CAR22161.1 - 2.7 8.7 23.4 0.74 10.5 0.5 5.2 4 2 1 5 5 5 0 SlyX DHR10 PF18595.1 CAR22161.1 - 5.7 7.0 35.3 0.68 10.0 16.6 4.1 3 1 1 5 5 5 0 Designed helical repeat protein 10 domain MscS_porin PF12795.7 CAR22161.1 - 6 6.3 40.9 2.5 7.6 33.2 3.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain SF3A2 PF16835.5 CAR22162.1 - 2.1e-22 79.3 0.1 3.9e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CAR22162.1 - 8.3e-07 29.2 1.1 2.1e-06 27.9 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAR22162.1 - 0.041 14.2 0.1 0.08 13.3 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PASTA PF03793.19 CAR22162.1 - 0.095 12.6 0.0 1 9.2 0.1 2.3 2 0 0 2 2 2 0 PASTA domain SIR2 PF02146.17 CAR22163.1 - 1.3e-67 227.1 0.0 2e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CAR22163.1 - 8.7e-62 207.4 0.3 1.4e-61 206.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 CAR22163.1 - 0.0037 17.0 0.0 0.58 9.9 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF327 PF03885.13 CAR22163.1 - 0.071 13.1 0.4 0.57 10.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HLH PF00010.26 CAR22164.1 - 5e-15 55.2 0.0 7.5e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Histone_HNS PF00816.21 CAR22164.1 - 0.029 15.2 0.0 0.074 13.9 0.0 1.7 2 0 0 2 2 2 0 H-NS histone family RRP14 PF15459.6 CAR22164.1 - 0.041 14.5 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 NARP1 PF12569.8 CAR22165.1 - 5.1e-113 378.7 25.0 9.4e-84 282.2 4.6 4.1 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CAR22165.1 - 1.2e-14 53.2 9.8 0.05 13.7 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAR22165.1 - 9.5e-09 35.4 1.3 3 8.9 0.0 6.7 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAR22165.1 - 3.2e-07 30.9 5.6 0.027 15.1 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR22165.1 - 1.3e-05 25.6 9.8 0.76 10.3 0.4 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAR22165.1 - 0.0011 19.2 12.1 0.12 12.7 0.1 5.2 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR22165.1 - 0.0012 18.5 9.5 4.1 7.4 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR22165.1 - 0.011 16.1 7.5 5.9 7.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR22165.1 - 0.031 14.5 14.2 5.5 7.5 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAR22165.1 - 0.048 14.3 0.0 1.7 9.4 0.0 3.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5411 PF17424.2 CAR22165.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5411) TPR_10 PF13374.6 CAR22165.1 - 0.14 12.1 3.6 16 5.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR22165.1 - 0.57 10.3 5.3 9.8 6.3 0.1 3.3 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CAR22165.1 - 1.8 8.9 12.8 0.4 10.9 1.3 4.0 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Inv-AAD PF18785.1 CAR22166.1 - 4.6e-38 130.0 0.0 8.6e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 CAR22166.1 - 1.4e-32 113.0 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 CAR22166.1 - 4.4e-18 65.0 0.0 1e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR22166.1 - 3.8e-05 23.5 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Exo_endo_phos PF03372.23 CAR22167.1 - 4.4e-07 29.6 0.0 6.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CAR22167.1 - 0.00099 18.9 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Git3 PF11710.8 CAR22168.1 - 9.9e-76 254.0 10.5 1.8e-75 253.2 10.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 CAR22168.1 - 2.3e-33 114.1 4.2 2.3e-33 114.1 4.2 2.4 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term MscS_TM PF12794.7 CAR22168.1 - 0.0042 16.0 2.6 0.0092 14.9 2.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 7tm_1 PF00001.21 CAR22168.1 - 0.008 15.5 0.4 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Inositol_P PF00459.25 CAR22169.1 - 6.5e-52 176.7 0.2 3.4e-51 174.4 0.2 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family tRNA_Me_trans PF03054.16 CAR22170.1 - 1.8e-107 359.2 0.0 2.1e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 CAR22170.1 - 0.054 12.6 0.0 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 NAD synthase DEAD PF00270.29 CAR22171.1 - 2.4e-48 164.2 0.0 1.9e-46 158.1 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR22171.1 - 6.9e-25 87.5 0.1 1.2e-21 77.1 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DBP10CT PF08147.12 CAR22171.1 - 9.5e-19 67.4 4.5 9.5e-19 67.4 4.5 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain DUF3449 PF11931.8 CAR22172.1 - 4.3e-68 228.8 0.1 9.6e-68 227.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) PRP9_N PF16958.5 CAR22172.1 - 3e-42 144.2 11.3 1.1e-41 142.3 3.6 2.6 3 0 0 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus SF3A3 PF16837.5 CAR22172.1 - 6.7e-18 65.0 1.3 6.7e-18 65.0 1.3 2.6 2 1 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 CAR22172.1 - 1.1e-07 31.9 0.7 7.1e-06 26.2 0.0 2.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR22172.1 - 2.3e-07 31.0 0.2 0.0031 17.8 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAR22172.1 - 0.019 15.3 0.1 1.5 9.2 0.0 3.3 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF3450 PF11932.8 CAR22172.1 - 0.08 12.2 0.1 0.08 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2914 PF11141.8 CAR22172.1 - 0.081 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) DUF3954 PF13128.6 CAR22172.1 - 0.36 10.7 0.8 1.8 8.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3954) IFT20 PF14931.6 CAR22172.1 - 0.49 10.6 4.0 2.2 8.5 0.3 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 CTP_transf_1 PF01148.20 CAR22173.1 - 1.1e-80 271.3 18.1 1.5e-80 270.8 18.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Pkinase PF00069.25 CAR22174.1 - 1.3e-61 208.3 0.0 2.9e-61 207.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22174.1 - 2.2e-32 112.4 0.0 8.3e-31 107.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CAR22174.1 - 0.00026 21.6 0.1 0.00089 19.9 0.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CAR22174.1 - 0.0072 15.7 0.0 0.036 13.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Mannosyl_trans3 PF11051.8 CAR22176.1 - 5.4e-66 222.7 0.0 8.7e-66 222.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative LMBR1 PF04791.16 CAR22176.1 - 0.27 10.1 0.1 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein NMO PF03060.15 CAR22177.1 - 3.8e-33 115.3 6.7 2.2e-23 83.2 3.8 2.3 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 CAR22177.1 - 3e-06 26.5 9.2 1.9e-05 23.9 9.2 1.9 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CAR22177.1 - 0.0001 21.5 2.3 0.0056 15.7 2.4 2.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CAR22177.1 - 0.099 11.8 2.7 0.2 10.8 2.7 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase ADH_zinc_N PF00107.26 CAR22178.1 - 2.8e-07 30.6 0.0 4.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR22178.1 - 0.00057 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DnaB_2 PF07261.11 CAR22178.1 - 0.023 14.4 0.0 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 Replication initiation and membrane attachment CSG2 PF16965.5 CAR22179.1 - 3.8e-127 424.6 20.8 6e-113 377.8 12.9 2.9 1 1 1 2 2 2 2 Ceramide synthase regulator NrsF PF06532.11 CAR22179.1 - 0.14 11.9 11.0 0.041 13.6 2.6 2.5 2 0 0 2 2 2 0 Negative regulator of sigma F HLH PF00010.26 CAR22180.1 - 1.9e-05 24.6 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain OCC1 PF15506.6 CAR22180.1 - 0.085 13.0 1.1 0.14 12.3 1.1 1.5 1 0 0 1 1 1 0 OCC1 family DUF1751 PF08551.10 CAR22181.1 - 1.1e-27 96.5 1.0 1.1e-27 96.5 1.0 2.4 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CAR22181.1 - 0.036 14.1 3.5 0.074 13.1 3.5 1.6 1 0 0 1 1 1 0 Rhomboid family DUF2678 PF10856.8 CAR22181.1 - 5.1 7.0 11.0 0.27 11.2 4.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) Ribosomal_L27A PF00828.19 CAR22182.1 - 1.8e-31 109.5 2.5 2.2e-31 109.2 0.9 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L18 PF17135.4 CAR22182.1 - 0.021 14.2 0.4 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein 60S L18 and 50S L18e WSC PF01822.19 CAR22183.1 - 4.3e-10 39.6 13.5 4.3e-10 39.6 13.5 3.5 2 1 0 2 2 2 1 WSC domain PTP_tm PF18861.1 CAR22183.1 - 0.0038 17.2 3.0 0.0038 17.2 3.0 2.0 1 1 1 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 CAR22183.1 - 0.02 14.3 0.7 0.26 10.7 0.7 3.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.9 CAR22183.1 - 0.032 13.0 0.0 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Mucin15 PF15672.5 CAR22183.1 - 0.06 12.8 49.7 0.094 12.2 49.7 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 LAP1C PF05609.12 CAR22183.1 - 0.21 10.7 23.7 0.3 10.1 23.7 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Syndecan PF01034.20 CAR22183.1 - 0.21 11.5 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.6 CAR22183.1 - 0.69 10.8 2.9 0.86 10.5 0.0 2.7 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Utp14 PF04615.13 CAR22183.1 - 1.3 7.5 21.8 1.8 7.0 21.8 1.2 1 0 0 1 1 1 0 Utp14 protein ABC_membrane PF00664.23 CAR22184.1 - 4.1e-61 207.1 38.9 2.6e-32 112.6 10.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAR22184.1 - 1.4e-47 161.7 0.1 3.2e-30 105.4 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR22184.1 - 9.4e-10 38.3 6.4 0.0045 16.5 2.6 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CAR22184.1 - 4.6e-08 33.1 0.0 0.0025 17.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CAR22184.1 - 9.2e-06 25.3 0.1 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CAR22184.1 - 1.2e-05 25.3 0.7 6.7 6.4 0.0 4.5 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CAR22184.1 - 7e-05 22.8 0.0 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CAR22184.1 - 0.00035 20.8 0.2 0.18 12.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.22 CAR22184.1 - 0.001 18.3 0.1 0.33 10.1 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain AAA_23 PF13476.6 CAR22184.1 - 0.0012 19.4 1.7 1.7 9.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CAR22184.1 - 0.0012 19.1 1.4 0.7 10.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAR22184.1 - 0.0013 18.8 0.4 0.075 13.1 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 CAR22184.1 - 0.0021 18.1 2.0 0.032 14.3 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 CAR22184.1 - 0.0027 18.1 0.3 0.59 10.5 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CAR22184.1 - 0.0092 15.7 0.2 8.9 6.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 CAR22184.1 - 0.01 16.4 0.1 8.9 6.9 0.0 3.8 4 0 0 4 4 3 0 AAA domain TsaE PF02367.17 CAR22184.1 - 0.015 15.3 0.0 0.96 9.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CAR22184.1 - 0.015 14.4 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 CAR22184.1 - 0.021 14.6 1.0 9.3 5.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 CAR22184.1 - 0.021 14.4 0.0 0.77 9.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 CAR22184.1 - 0.027 13.4 0.1 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 CAR22184.1 - 0.036 13.3 0.2 4.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CAR22184.1 - 0.039 13.3 0.4 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2207 PF09972.9 CAR22184.1 - 0.072 11.9 0.0 0.072 11.9 0.0 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) AAA_15 PF13175.6 CAR22184.1 - 0.078 12.7 0.1 3.9 7.1 0.0 3.1 2 2 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 CAR22184.1 - 0.12 12.1 0.1 7.1 6.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CAR22184.1 - 0.51 10.2 2.2 2.8 7.8 0.0 2.9 3 0 0 3 3 3 0 NACHT domain RNase_P_pop3 PF08228.11 CAR22185.1 - 5.7e-44 150.0 0.0 7.2e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 RNase P subunit Pop3 Aha1_N PF09229.11 CAR22186.1 - 1.8e-28 99.5 0.0 2.5e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal ERG4_ERG24 PF01222.17 CAR22187.1 - 1.2e-165 551.5 10.8 1.4e-165 551.3 10.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CAR22187.1 - 9.8e-05 22.0 0.2 0.00018 21.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Sec20 PF03908.13 CAR22189.1 - 7.8e-24 83.4 0.7 7.8e-24 83.4 0.7 1.9 2 0 0 2 2 2 1 Sec20 FGase PF05013.12 CAR22189.1 - 0.016 15.4 0.2 0.047 13.9 0.0 1.8 1 1 1 2 2 2 0 N-formylglutamate amidohydrolase DUF1104 PF06518.11 CAR22189.1 - 0.07 13.5 1.0 0.21 12.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF3835 PF12927.7 CAR22189.1 - 0.087 13.7 2.5 0.16 12.9 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) Perilipin PF03036.16 CAR22189.1 - 1.3 8.0 15.2 0.075 12.1 5.2 2.1 2 0 0 2 2 2 0 Perilipin family MRP-S26 PF14943.6 CAR22189.1 - 9.5 6.1 10.4 0.89 9.4 5.7 1.7 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S26 Sugar_tr PF00083.24 CAR22190.1 - 9.4e-130 433.5 25.0 1.2e-129 433.2 25.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR22190.1 - 3.9e-30 105.0 33.6 8.8e-30 103.8 25.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR22190.1 - 4.5e-05 22.1 4.1 4.5e-05 22.1 4.1 1.9 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CAR22190.1 - 0.0044 15.5 0.4 0.0084 14.6 0.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2530 PF10745.9 CAR22190.1 - 2.8 8.3 9.2 1.7 8.9 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) CPL PF08144.11 CAR22191.1 - 6.3e-50 169.2 7.1 1.3e-47 161.7 0.1 4.8 4 1 0 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 CAR22191.1 - 0.00018 21.0 1.8 18 5.3 0.0 5.6 5 0 0 5 5 5 1 Pumilio-family RNA binding repeat Fungal_TACC PF12709.7 CAR22191.1 - 0.05 14.0 0.3 0.05 14.0 0.3 5.1 6 1 0 6 6 6 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4253 PF14062.6 CAR22191.1 - 0.086 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) HV_small_capsid PF17086.5 CAR22191.1 - 0.1 12.9 0.2 1 9.7 0.1 2.6 1 1 1 2 2 2 0 Small capsid protein of Herpesviridae ArlS_N PF18719.1 CAR22192.1 - 0.045 14.0 1.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 ArlS sensor domain Ribosomal_L23eN PF03939.13 CAR22193.1 - 0.067 13.4 2.5 0.14 12.4 0.8 2.4 2 0 0 2 2 2 0 Ribosomal protein L23, N-terminal domain PTS_2-RNA PF01885.16 CAR22194.1 - 1.2e-55 188.4 0.1 1.6e-55 188.0 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 CAR22194.1 - 0.0058 16.7 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 La domain S-antigen PF05756.11 CAR22195.1 - 0.037 14.4 0.4 0.24 11.8 0.3 1.9 1 1 1 2 2 2 0 S-antigen protein HlyIII PF03006.20 CAR22196.1 - 3.4e-54 183.9 21.7 4.1e-54 183.7 21.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.25 CAR22198.1 - 8.4e-64 215.5 0.3 1.6e-63 214.6 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22198.1 - 8.6e-36 123.5 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22198.1 - 1.9e-08 34.0 0.1 5.6e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CAR22198.1 - 4e-06 26.0 1.1 7.2e-06 25.2 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 CAR22198.1 - 4.1e-05 23.3 3.0 0.047 13.3 0.1 3.0 1 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CAR22198.1 - 0.00038 19.3 1.4 0.00059 18.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CAR22198.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 CAR22198.1 - 0.024 13.5 0.0 0.051 12.4 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 CAR22198.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M16_C PF05193.21 CAR22199.1 - 1.2e-15 58.0 0.0 7.1e-14 52.2 0.0 3.7 4 1 1 5 5 5 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR22199.1 - 3e-10 40.3 0.0 1.9e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Elongin_A PF06881.11 CAR22199.1 - 0.0097 16.4 2.1 0.038 14.5 1.1 2.3 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Sigma70_r1_1 PF03979.14 CAR22199.1 - 0.033 14.2 4.1 0.051 13.6 1.9 2.5 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 SLD5_C PF16922.5 CAR22200.1 - 8.7e-22 77.1 0.3 2.4e-21 75.7 0.3 1.8 2 0 0 2 2 2 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CAR22200.1 - 1.3e-11 44.9 0.6 2.4e-11 44.0 0.6 1.4 1 0 0 1 1 1 1 GINS complex protein DUF2387 PF09526.10 CAR22200.1 - 0.1 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) PhoR PF11808.8 CAR22202.1 - 0.2 12.1 0.2 0.73 10.3 0.0 1.8 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR DUF1091 PF06477.13 CAR22203.1 - 0.049 14.1 0.0 0.056 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) DHBP_synthase PF00926.19 CAR22204.1 - 1e-80 269.8 0.1 1.2e-80 269.6 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase tRNA-synt_1b PF00579.25 CAR22205.1 - 1.9e-18 66.8 0.0 3.6e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Snf7 PF03357.21 CAR22206.1 - 3.9e-38 130.7 17.0 4.8e-38 130.4 17.0 1.1 1 0 0 1 1 1 1 Snf7 Fmp27_WPPW PF10359.9 CAR22206.1 - 0.0011 18.0 5.8 0.0015 17.5 5.8 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.7 CAR22206.1 - 0.02 15.0 9.5 0.032 14.4 8.9 1.7 1 1 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.9 CAR22206.1 - 0.029 14.7 14.7 0.11 12.8 1.8 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1411 PF07199.11 CAR22206.1 - 0.061 13.0 3.1 0.11 12.2 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1411) Fib_alpha PF08702.10 CAR22206.1 - 0.09 13.0 12.6 0.59 10.3 2.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_S46 PF10459.9 CAR22206.1 - 0.15 10.7 9.6 0.18 10.4 9.6 1.0 1 0 0 1 1 1 0 Peptidase S46 KASH_CCD PF14662.6 CAR22206.1 - 0.16 11.7 19.2 1.1 9.1 7.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH SKA1 PF07160.12 CAR22206.1 - 0.18 11.7 12.8 0.57 10.0 12.8 1.8 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0242 PF06785.11 CAR22206.1 - 0.33 11.0 16.2 1 9.4 8.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 CAR22206.1 - 0.58 9.5 9.7 0.88 8.9 9.7 1.2 1 0 0 1 1 1 0 FAM76 protein Not3 PF04065.15 CAR22206.1 - 0.61 9.5 13.2 1.7 8.0 13.2 1.8 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component COG2 PF06148.11 CAR22206.1 - 0.73 9.9 7.6 0.83 9.7 3.9 2.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_L PF02601.15 CAR22206.1 - 1.5 8.3 12.6 2 7.9 12.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 CAR22206.1 - 1.5 6.2 19.0 2 5.8 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC_tran_CTD PF16326.5 CAR22206.1 - 1.6 9.0 12.7 3.1 8.1 1.5 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain Gluconate_2-dh3 PF13618.6 CAR22206.1 - 2.1 8.6 6.1 10 6.4 6.1 2.3 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 YlqD PF11068.8 CAR22206.1 - 3 8.2 19.7 0.098 13.0 10.0 2.2 1 1 1 2 2 2 0 YlqD protein KxDL PF10241.9 CAR22206.1 - 3.2 8.1 13.5 0.18 12.1 1.2 3.0 2 1 0 2 2 2 0 Uncharacterized conserved protein Prefoldin PF02996.17 CAR22206.1 - 4.1 7.3 13.6 0.38 10.7 2.4 3.3 2 1 2 4 4 4 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 CAR22206.1 - 5 7.3 16.0 3.3 7.9 7.7 2.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 COG6 PF06419.11 CAR22206.1 - 5.7 5.0 15.1 0.35 9.0 6.2 2.0 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 DUF1664 PF07889.12 CAR22206.1 - 6.3 6.9 13.7 0.76 9.8 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Methyltransf_23 PF13489.6 CAR22207.1 - 5.4e-23 81.6 0.0 8.1e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR22207.1 - 3.9e-16 59.5 0.0 6.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR22207.1 - 4.2e-15 55.8 0.0 6.6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR22207.1 - 2.2e-14 53.9 0.0 4.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR22207.1 - 9.2e-13 48.8 0.0 1.7e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAR22207.1 - 3.9e-08 32.9 0.0 5.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CAR22207.1 - 1.1e-06 28.3 0.0 2.4e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CAR22207.1 - 1.3e-06 28.0 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CAR22207.1 - 1.4e-06 28.0 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 CAR22207.1 - 3.5e-05 23.0 0.0 6.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase MetW PF07021.12 CAR22207.1 - 0.00033 20.3 0.0 0.00056 19.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 CAR22207.1 - 0.00058 18.9 0.0 0.00085 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 CAR22207.1 - 0.00072 19.6 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CAR22207.1 - 0.0058 16.6 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CAR22207.1 - 0.0058 16.1 0.0 1.2 8.6 0.0 2.6 2 1 0 3 3 3 1 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.18 CAR22207.1 - 0.0064 15.9 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CAR22207.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AviRa PF11599.8 CAR22207.1 - 0.013 15.0 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Spermine_synth PF01564.17 CAR22207.1 - 0.029 13.8 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain RrnaAD PF00398.20 CAR22207.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase YL1 PF05764.13 CAR22208.1 - 5.1e-48 164.3 39.9 5.1e-48 164.3 39.9 3.2 2 1 1 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 CAR22208.1 - 2.3e-12 46.4 0.6 3.7e-12 45.8 0.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain UvrD_C PF13361.6 CAR22209.1 - 1.6e-31 110.0 0.0 2.7e-29 102.7 0.0 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CAR22209.1 - 4.3e-30 105.3 0.3 1.1e-13 51.4 0.0 2.9 2 1 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CAR22209.1 - 1.5e-25 90.3 0.1 6.4e-25 88.2 0.0 2.1 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 CAR22209.1 - 2.9e-12 46.8 0.0 0.00014 21.7 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CAR22209.1 - 1e-11 44.5 0.0 2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CAR22209.1 - 1.3e-05 25.0 0.0 0.0046 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CAR22209.1 - 3.7e-05 23.6 0.0 0.00066 19.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CAR22209.1 - 7.3e-05 22.5 0.0 0.086 12.5 0.0 3.8 3 1 0 3 3 3 1 AAA domain DEAD PF00270.29 CAR22209.1 - 0.00025 20.9 0.2 0.0016 18.3 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 CAR22209.1 - 0.029 14.2 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Helicase Vps52 PF04129.12 CAR22210.1 - 8.1e-132 440.5 14.1 1.1e-131 440.1 14.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family DUF3552 PF12072.8 CAR22210.1 - 0.05 13.0 0.6 0.088 12.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2408 PF10303.9 CAR22210.1 - 0.96 10.0 7.2 2.4 8.7 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Rep_fac_C PF08542.11 CAR22211.1 - 6.4e-21 74.6 0.0 2e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CAR22211.1 - 3.9e-13 49.5 0.1 4.7e-10 39.5 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 CAR22211.1 - 9.8e-13 48.7 0.0 2.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR22211.1 - 5.5e-07 30.1 0.0 4.1e-05 24.0 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 CAR22211.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CAR22211.1 - 4.4e-06 26.6 0.0 1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR22211.1 - 2.3e-05 24.7 0.2 0.043 14.1 0.0 2.7 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 CAR22211.1 - 9.7e-05 22.2 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CAR22211.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CAR22211.1 - 0.00024 20.9 0.0 0.00063 19.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CAR22211.1 - 0.00034 20.0 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 CAR22211.1 - 0.00039 20.3 0.2 0.00072 19.4 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 CAR22211.1 - 0.00084 19.6 0.0 0.0029 17.9 0.0 1.9 2 0 0 2 2 2 1 AAA C-terminal domain MeaB PF03308.16 CAR22211.1 - 0.004 16.2 0.0 0.02 13.9 0.0 2.0 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TniB PF05621.11 CAR22211.1 - 0.0049 16.3 0.1 1.8 7.9 0.0 2.4 1 1 0 2 2 2 1 Bacterial TniB protein KTI12 PF08433.10 CAR22211.1 - 0.0088 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SRP54 PF00448.22 CAR22211.1 - 0.045 13.4 0.0 0.085 12.5 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CAR22211.1 - 0.054 13.8 0.1 0.25 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAR22211.1 - 0.056 13.2 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CAR22211.1 - 0.084 12.8 0.1 0.36 10.7 0.1 2.0 1 1 1 2 2 2 0 NTPase MCM PF00493.23 CAR22211.1 - 0.088 11.9 0.0 0.2 10.7 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AAA_11 PF13086.6 CAR22211.1 - 0.1 12.3 0.1 0.18 11.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CAR22211.1 - 0.12 12.0 0.0 0.4 10.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain tRNA_m1G_MT PF01746.21 CAR22212.1 - 9.9e-29 100.4 1.6 1.2e-28 100.2 0.1 1.8 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase MPM1 PF17234.2 CAR22212.1 - 0.037 14.3 10.9 0.28 11.4 5.5 2.3 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 MIT PF04212.18 CAR22212.1 - 0.039 14.0 1.5 0.11 12.6 1.5 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain PQ-loop PF04193.14 CAR22213.1 - 3.9e-38 129.0 19.7 2.7e-21 75.1 3.0 2.9 3 0 0 3 3 3 2 PQ loop repeat Bac_export_2 PF01312.19 CAR22213.1 - 0.097 11.9 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF4538 PF15061.6 CAR22213.1 - 0.18 11.6 0.2 0.75 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DegS PF05384.11 CAR22214.1 - 0.0013 18.2 24.9 0.078 12.5 2.3 2.9 1 1 0 2 2 2 2 Sensor protein DegS DNA_pol_D_N PF18018.1 CAR22214.1 - 0.31 11.1 2.9 0.34 11.0 0.0 2.4 3 0 0 3 3 3 0 DNA polymerase delta subunit OB-fold domain ERM PF00769.19 CAR22214.1 - 0.36 10.6 34.9 1.6 8.5 19.1 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.9 CAR22214.1 - 3.6 7.9 18.0 0.1 12.9 5.5 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MutS_V PF00488.21 CAR22215.1 - 1.6e-83 279.3 0.5 3.3e-83 278.4 0.5 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR22215.1 - 4.1e-32 112.0 1.9 8.9e-32 110.9 0.1 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CAR22215.1 - 2e-20 73.5 0.1 7.4e-20 71.6 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CAR22215.1 - 4.5e-17 62.2 0.3 1e-16 61.1 0.3 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 CAR22215.1 - 9.7e-10 38.7 0.0 4.1e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 CAR22215.1 - 0.056 13.0 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Aldo_ket_red PF00248.21 CAR22216.1 - 4.3e-42 144.3 0.0 4.5e-40 137.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 CAR22217.1 - 4.2e-15 55.5 1.4 8.9e-15 54.4 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22217.1 - 1e-08 35.1 10.2 2.3e-08 34.0 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.12 CAR22218.1 - 4e-49 167.2 0.0 5e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-PARP PF00645.18 CAR22218.1 - 0.0033 18.3 2.5 0.0056 17.5 2.1 1.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Thioredoxin PF00085.20 CAR22219.1 - 4.2e-12 45.9 0.0 9.1e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAR22219.1 - 0.0024 18.1 0.1 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CAR22219.1 - 0.077 12.9 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family REV1_C PF16727.5 CAR22219.1 - 0.98 9.9 3.9 7.5 7.0 0.0 3.3 2 1 2 4 4 4 0 DNA repair protein REV1 C-terminal domain Zn_clus PF00172.18 CAR22220.1 - 1.9e-08 34.3 8.3 3.5e-08 33.4 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR22220.1 - 0.0013 17.8 1.6 0.0013 17.8 1.6 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CAR22221.1 - 4.8e-39 134.3 47.8 1.7e-29 102.9 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR22221.1 - 4.1e-11 42.0 14.8 4.1e-11 42.0 14.8 2.8 1 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CAR22221.1 - 5.2e-06 26.0 10.5 5.2e-06 26.0 10.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 CAR22222.1 - 5.8e-31 107.7 60.5 2.3e-29 102.4 33.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR22222.1 - 0.00026 19.5 33.6 0.0032 15.9 33.4 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MscL PF01741.18 CAR22222.1 - 4.7 7.5 0.0 4.7 7.5 0.0 4.0 5 1 0 5 5 5 0 Large-conductance mechanosensitive channel, MscL Aldolase_II PF00596.21 CAR22223.1 - 3e-50 170.8 0.1 3.8e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain NUDIX PF00293.28 CAR22224.1 - 3.7e-20 72.3 0.4 4.9e-20 71.9 0.4 1.2 1 0 0 1 1 1 1 NUDIX domain DUF3225 PF11533.8 CAR22224.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) DUF410 PF04190.13 CAR22225.1 - 1.1e-79 267.8 0.1 1.3e-79 267.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RHD3 PF05879.12 CAR22226.1 - 9.1e-244 811.0 15.9 1.1e-243 810.7 15.9 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CAR22226.1 - 9.4e-06 25.8 0.0 4.1e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CAR22226.1 - 6.2e-05 23.1 0.0 0.00021 21.3 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 CAR22226.1 - 0.0084 15.4 0.2 0.069 12.4 0.1 2.3 2 0 0 2 2 2 1 Septin AAA_28 PF13521.6 CAR22226.1 - 0.06 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CAR22226.1 - 0.1 12.5 0.9 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase XLF PF09302.11 CAR22227.1 - 6.8e-06 26.4 0.4 1.5e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component PIN_4 PF13638.6 CAR22228.1 - 2.5e-32 111.9 0.1 5.1e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 CAR22228.1 - 0.0019 18.5 0.1 0.22 11.8 0.1 2.6 1 1 0 1 1 1 1 PIN like domain Ribosomal_S28e PF01200.18 CAR22229.1 - 1.6e-32 111.2 2.0 1.8e-32 111.1 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 CAR22229.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Red1 PF07964.11 CAR22230.1 - 2.2e-69 234.6 19.3 6.3e-43 147.1 3.4 2.7 1 1 1 2 2 2 2 Rec10 / Red1 Nup88 PF10168.9 CAR22230.1 - 0.0056 14.6 0.3 0.018 12.9 0.0 1.8 2 0 0 2 2 2 1 Nuclear pore component tRNA-synt_1c PF00749.21 CAR22231.1 - 3.6e-117 390.8 0.0 5e-117 390.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CAR22231.1 - 8.3e-53 178.7 0.2 1.4e-52 178.0 0.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CAR22231.1 - 4.1e-35 121.2 0.2 1.2e-33 116.5 0.2 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CAR22231.1 - 1.1e-13 51.9 1.3 3.8e-13 50.2 1.3 1.9 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TMA7 PF09072.10 CAR22232.1 - 3.6e-21 75.8 18.1 3.9e-21 75.6 18.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 DUF5633 PF18656.1 CAR22232.1 - 0.011 15.6 0.9 0.014 15.2 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Ras PF00071.22 CAR22233.1 - 1.2e-56 190.7 0.8 1.6e-56 190.4 0.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR22233.1 - 1.5e-37 128.5 0.2 3e-37 127.5 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR22233.1 - 3.2e-16 59.3 0.5 4.4e-16 58.8 0.5 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CAR22233.1 - 8.4e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAR22233.1 - 2.5e-05 24.3 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR22233.1 - 2.6e-05 24.2 0.2 0.035 14.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CAR22233.1 - 4.5e-05 22.9 0.4 6.4e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR22233.1 - 0.00011 21.8 0.2 0.00082 19.0 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 CAR22233.1 - 0.0019 18.2 0.5 0.0075 16.2 0.0 1.9 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CAR22233.1 - 0.0054 16.3 0.0 0.0096 15.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CAR22233.1 - 0.014 15.6 0.0 0.05 13.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 CAR22233.1 - 0.017 14.9 0.2 0.023 14.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAR22233.1 - 0.027 14.8 0.0 0.041 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CAR22233.1 - 0.032 14.0 0.2 0.062 13.0 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 CAR22233.1 - 0.052 13.5 0.2 0.08 12.9 0.1 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CAR22233.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 CAR22233.1 - 0.11 12.5 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DAGK_cat PF00781.24 CAR22234.1 - 6.5e-27 93.7 0.0 1.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cpn60_TCP1 PF00118.24 CAR22235.1 - 1.9e-82 277.5 11.5 5.1e-82 276.1 11.5 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family cobW PF02492.19 CAR22236.1 - 1.4e-45 155.1 7.2 2.7e-43 147.6 7.2 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CAR22236.1 - 9.9e-20 70.3 0.0 1e-14 54.2 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain YlbD_coat PF14071.6 CAR22236.1 - 0.0017 18.6 5.4 0.0017 18.6 5.4 3.3 3 1 0 3 3 2 1 Putative coat protein MobB PF03205.14 CAR22236.1 - 0.0048 16.8 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2052 PF09747.9 CAR22236.1 - 0.0073 16.5 16.7 0.15 12.2 5.5 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) T2SSE PF00437.20 CAR22236.1 - 0.023 13.8 0.1 0.047 12.7 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein CDC45 PF02724.14 CAR22236.1 - 0.065 11.5 16.9 0.012 13.9 3.5 2.2 2 0 0 2 2 2 0 CDC45-like protein Viral_helicase1 PF01443.18 CAR22236.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 CAR22236.1 - 0.12 12.2 0.3 0.33 10.7 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TsaE PF02367.17 CAR22236.1 - 0.14 12.2 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CAR22236.1 - 0.15 12.4 2.1 0.17 12.3 0.0 2.1 3 0 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.6 CAR22236.1 - 0.16 12.3 0.2 0.34 11.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 CAR22236.1 - 0.2 10.6 1.6 3.3 6.6 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4746 PF15928.5 CAR22236.1 - 0.35 10.2 15.8 0.19 11.1 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) GEN1_C PF18380.1 CAR22236.1 - 0.39 11.6 8.9 6.3 7.7 2.3 2.7 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain DUF2201_N PF13203.6 CAR22236.1 - 3.3 7.2 10.6 0.7 9.4 3.4 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Merozoite_SPAM PF07133.11 CAR22236.1 - 3.6 7.5 41.8 4.3 7.3 23.7 2.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Nop14 PF04147.12 CAR22236.1 - 3.6 5.7 27.4 0.2 9.8 11.8 2.1 2 0 0 2 2 2 0 Nop14-like family Paf1 PF03985.13 CAR22236.1 - 3.8 6.4 27.9 1.9 7.4 13.2 2.1 2 0 0 2 2 2 0 Paf1 Mpp10 PF04006.12 CAR22236.1 - 4.2 5.7 27.0 2.2 6.6 12.9 2.2 2 0 0 2 2 2 0 Mpp10 protein DUF4637 PF15470.6 CAR22236.1 - 5.3 6.7 25.2 1.3 8.7 10.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) SDA1 PF05285.12 CAR22236.1 - 7.6 5.8 31.1 1.9 7.9 12.9 2.2 2 0 0 2 2 2 0 SDA1 PTPRCAP PF15713.5 CAR22236.1 - 8.5 6.7 29.3 4.6 7.5 12.2 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Fungal_trans PF04082.18 CAR22238.1 - 5e-14 52.0 0.0 7.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22238.1 - 5.6e-09 36.0 8.1 5.6e-09 36.0 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 CAR22239.1 - 6.1e-15 55.4 0.2 5e-14 52.4 0.2 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR22239.1 - 7.1e-12 46.5 0.0 1.3e-11 45.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CAR22239.1 - 0.0044 16.5 0.1 0.0067 15.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GvpG PF05120.12 CAR22239.1 - 0.061 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G NmrA PF05368.13 CAR22239.1 - 0.086 12.4 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 CAR22239.1 - 0.12 12.5 0.3 0.12 12.5 0.3 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.16 CAR22240.1 - 4.2e-45 154.2 50.9 1.1e-44 152.9 50.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily RNA_pol_I_TF PF04090.12 CAR22241.1 - 3.2e-62 209.6 0.0 5.6e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor AAA_33 PF13671.6 CAR22241.1 - 0.58 10.3 3.1 5.4 7.2 1.3 2.4 1 1 1 2 2 2 0 AAA domain zf-RING_2 PF13639.6 CAR22242.1 - 2.3e-09 37.4 10.0 6.3e-09 36.0 10.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CAR22242.1 - 2.6e-06 27.6 9.6 5.4e-06 26.6 9.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CAR22242.1 - 0.00027 20.7 9.2 0.00064 19.5 9.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR22242.1 - 0.0016 18.4 4.7 0.0016 18.4 4.7 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAR22242.1 - 0.0019 18.1 7.2 0.0044 16.9 7.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CAR22242.1 - 0.0032 17.3 7.5 0.0068 16.3 7.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CAR22242.1 - 0.0041 17.0 10.6 0.0041 17.0 10.6 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR22242.1 - 0.006 16.4 13.0 0.039 13.8 13.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAR22242.1 - 0.0066 16.5 1.4 0.014 15.4 1.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Pox_A_type_inc PF04508.12 CAR22242.1 - 0.023 14.5 3.0 0.054 13.4 3.0 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat zf-RING_4 PF14570.6 CAR22242.1 - 0.41 10.5 5.8 9.7 6.1 6.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CAR22242.1 - 1.1 9.5 5.0 4.4 7.5 5.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CAR22242.1 - 1.5 8.5 7.1 0.13 12.0 2.1 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CAR22242.1 - 8.2 6.3 9.5 3.3 7.5 5.5 2.5 2 1 0 2 2 2 0 RING-like zinc finger OPA3 PF07047.12 CAR22243.1 - 8.2e-42 141.9 0.1 9.4e-42 141.7 0.1 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) bZIP_2 PF07716.15 CAR22243.1 - 0.32 11.1 4.7 0.6 10.2 4.7 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Histone PF00125.24 CAR22244.1 - 1e-14 55.0 0.0 1.2e-14 54.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CAR22244.1 - 1.8e-12 46.8 0.1 2.8e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CAR22244.1 - 0.001 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.18 CAR22245.1 - 6.2e-221 734.0 5.0 7.7e-221 733.7 5.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CAR22245.1 - 0.0084 16.3 1.9 0.015 15.5 1.9 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain PilM_2 PF11104.8 CAR22245.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; TAF4 PF05236.14 CAR22246.1 - 1e-55 189.4 5.9 1e-55 189.4 5.9 2.8 3 0 0 3 3 3 1 Transcription initiation factor TFIID component TAF4 family TFIID_30kDa PF03540.13 CAR22246.1 - 0.078 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.24 CAR22246.1 - 0.31 11.4 0.0 0.31 11.4 0.0 3.4 4 0 0 4 4 4 0 Core histone H2A/H2B/H3/H4 Glypican PF01153.19 CAR22246.1 - 0.61 8.9 6.9 1.1 8.0 6.9 1.3 1 0 0 1 1 1 0 Glypican Suf PF05843.14 CAR22246.1 - 5.6 6.8 19.7 65 3.4 19.7 2.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) ASD2 PF08687.11 CAR22246.1 - 8.5 5.8 12.4 0.75 9.3 4.6 2.2 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 RTC PF01137.21 CAR22247.1 - 3.9e-44 150.5 0.0 4.5e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CAR22247.1 - 2.4e-32 111.5 0.0 3.8e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.24 CAR22248.1 - 5.1e-20 71.5 0.1 1.2e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 PX domain BRE1 PF08647.11 CAR22248.1 - 0.09 12.9 0.5 0.21 11.7 0.5 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF4164 PF13747.6 CAR22248.1 - 1.3 9.4 5.0 9.3 6.6 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) MMM1 PF10296.9 CAR22249.1 - 2.7e-09 36.6 0.0 1.1e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Polyketide_cyc PF03364.20 CAR22250.1 - 6.3e-19 68.5 0.0 7.7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CAR22250.1 - 0.00054 20.2 0.0 0.00071 19.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SAP PF02037.27 CAR22251.1 - 2.6e-09 36.6 0.1 5.9e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 SAP domain DUF2076 PF09849.9 CAR22252.1 - 8.7e-05 22.7 11.9 0.00011 22.3 11.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CAR22252.1 - 0.00016 21.7 4.3 0.00024 21.1 4.3 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 CAR22252.1 - 0.11 12.7 3.5 0.2 11.9 3.5 1.3 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type TFIIA PF03153.13 CAR22252.1 - 8.8 6.2 9.2 10 6.0 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Topoisom_I_N PF02919.15 CAR22254.1 - 5.3e-98 326.8 0.8 5.3e-98 326.8 0.8 2.8 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 CAR22254.1 - 2.3e-97 324.8 0.5 2.3e-97 324.8 0.5 3.0 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 CAR22254.1 - 2e-33 114.1 0.4 9.3e-33 112.0 0.4 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain MethyltransfD12 PF02086.15 CAR22254.1 - 0.0055 16.4 9.5 0.016 14.9 6.6 2.6 1 1 1 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase Pkinase PF00069.25 CAR22255.1 - 3e-74 249.7 0.0 4.7e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22255.1 - 4.1e-38 131.1 0.0 6e-38 130.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CAR22255.1 - 2.1e-27 95.1 0.0 5.7e-14 52.0 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CAR22255.1 - 9.4e-09 35.0 0.0 4.9e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAR22255.1 - 0.014 14.8 0.2 0.04 13.3 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.11 CAR22255.1 - 0.018 15.3 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Haspin_kinase PF12330.8 CAR22255.1 - 0.053 12.5 0.1 0.053 12.5 0.1 2.0 2 1 0 2 2 2 0 Haspin like kinase domain RNA_pol_L_2 PF13656.6 CAR22256.1 - 1.2e-24 85.9 0.0 1.5e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CAR22256.1 - 9.1e-09 34.6 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sin3a_C PF16879.5 CAR22257.1 - 5.5e-80 269.1 5.6 5.5e-80 269.1 5.6 3.1 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 CAR22257.1 - 6.8e-46 154.2 9.0 3.6e-18 65.4 2.4 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CAR22257.1 - 2.1e-42 143.1 0.2 7.4e-42 141.4 0.2 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor CP_ATPgrasp_2 PF14403.6 CAR22257.1 - 0.097 11.6 0.2 0.23 10.3 0.2 1.5 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 DHHC PF01529.20 CAR22258.1 - 1.9e-30 105.7 13.0 1.9e-30 105.7 13.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase HlyIII PF03006.20 CAR22259.1 - 1.7e-54 184.9 18.0 2.1e-54 184.6 18.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Arteri_GP4 PF02497.15 CAR22259.1 - 0.0038 17.4 0.7 0.0065 16.6 0.7 1.3 1 0 0 1 1 1 1 Arterivirus glycoprotein DNA_pol_A_exo1 PF01612.20 CAR22260.1 - 5.7e-44 149.9 0.7 8.8e-44 149.3 0.7 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CAR22260.1 - 2.1e-18 66.8 2.7 9.4e-18 64.7 0.2 2.7 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 CAR22260.1 - 4.7e-10 39.3 0.1 1.4e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 HRDC domain Cyclin PF08613.11 CAR22261.1 - 2.8e-34 118.8 0.1 2.8e-34 118.8 0.1 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CAR22261.1 - 0.007 16.1 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ras PF00071.22 CAR22262.1 - 1.3e-56 190.7 0.2 1.6e-56 190.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR22262.1 - 2.5e-34 118.1 0.1 3.9e-34 117.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR22262.1 - 8.7e-15 54.6 0.0 9.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR22262.1 - 1.2e-06 28.0 0.1 1.5e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR22262.1 - 1.9e-06 27.9 0.0 2.9e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR22262.1 - 1.6e-05 24.5 0.2 0.00086 18.9 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAR22262.1 - 0.00024 20.6 0.1 0.0003 20.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CAR22262.1 - 0.0006 19.8 0.1 0.035 14.0 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 CAR22262.1 - 0.0038 17.0 0.2 0.076 12.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CAR22262.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.15 CAR22262.1 - 0.0056 16.6 0.1 0.032 14.1 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_16 PF13191.6 CAR22262.1 - 0.013 15.9 0.0 0.019 15.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CAR22262.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein cobW PF02492.19 CAR22262.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 CAR22262.1 - 0.024 14.0 0.2 0.41 9.9 0.1 2.1 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 CAR22262.1 - 0.03 14.1 0.3 0.065 13.0 0.1 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CAR22262.1 - 0.031 14.0 0.1 0.088 12.5 0.0 1.8 2 1 1 3 3 3 0 AAA domain NACHT PF05729.12 CAR22262.1 - 0.035 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CAR22262.1 - 0.037 13.5 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CAR22262.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.4 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 CAR22262.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pirin PF02678.16 CAR22263.1 - 4.9e-29 100.5 0.2 8.7e-28 96.4 0.0 2.2 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 CAR22263.1 - 6.9e-20 71.4 0.0 1.8e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CAR22263.1 - 1.5e-05 24.7 1.2 0.0012 18.6 0.7 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CAR22263.1 - 0.092 12.5 0.1 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Alg6_Alg8 PF03155.15 CAR22264.1 - 1.1e-143 479.7 27.3 1.4e-143 479.4 27.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SGTA_dimer PF16546.5 CAR22265.1 - 6.5e-23 80.3 0.6 1.3e-22 79.3 0.6 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 CAR22265.1 - 1.4e-19 69.0 4.3 5.3e-07 29.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR22265.1 - 3.5e-17 61.0 6.5 1e-05 25.2 0.1 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAR22265.1 - 8.9e-11 41.3 7.3 0.00015 21.4 1.9 3.6 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 CAR22265.1 - 6.6e-09 35.3 8.1 0.0013 18.8 0.6 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAR22265.1 - 2.5e-07 30.3 4.2 0.018 14.9 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR22265.1 - 8.2e-07 29.2 5.0 0.011 16.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR22265.1 - 8.6e-07 29.3 0.9 0.098 13.5 0.1 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR22265.1 - 1.8e-06 27.9 4.6 0.035 14.5 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAR22265.1 - 6.5e-06 26.7 3.6 6.5e-06 26.7 3.6 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR22265.1 - 0.00011 22.7 6.8 0.00036 21.0 0.2 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 CAR22265.1 - 0.00011 22.7 0.9 0.0013 19.1 0.2 2.3 1 1 0 2 2 2 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 CAR22265.1 - 0.00053 19.8 1.7 7 6.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR22265.1 - 0.00095 19.7 3.4 0.061 14.0 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR22265.1 - 0.0016 18.6 0.2 0.071 13.3 0.1 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat HMD PF03201.16 CAR22265.1 - 0.0018 18.4 1.0 0.0047 17.1 1.0 1.7 1 0 0 1 1 1 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase STI1 PF17830.1 CAR22265.1 - 0.0037 17.2 10.7 0.0037 17.2 10.7 2.5 1 1 0 2 2 2 1 STI1 domain Fis1_TPR_C PF14853.6 CAR22265.1 - 0.025 14.6 2.2 27 4.9 0.0 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CAR22265.1 - 0.032 14.4 2.8 0.058 13.6 1.4 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CAR22265.1 - 0.069 13.8 0.1 0.24 12.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF627 PF04781.12 CAR22265.1 - 0.18 11.8 1.4 13 5.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF627) DUF3856 PF12968.7 CAR22265.1 - 1.3 9.1 5.1 12 6.0 2.1 3.2 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) T3SS_needle_F PF09392.10 CAR22265.1 - 4.9 7.4 11.4 1.2 9.3 2.5 3.5 4 0 0 4 4 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF VPS9 PF02204.18 CAR22266.1 - 7.6e-14 51.8 0.7 5.4e-13 49.1 0.2 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 CAR22266.1 - 0.00043 20.5 0.2 0.0043 17.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR22266.1 - 0.039 14.5 0.2 3.8 8.2 0.0 2.9 1 1 2 3 3 3 0 Ankyrin repeats (3 copies) Ribo_biogen_C PF04034.13 CAR22267.1 - 5.3e-51 171.6 0.0 7.8e-51 171.1 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CAR22267.1 - 6.7e-16 57.8 0.3 1.2e-15 57.1 0.3 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DNA_ligase_A_M PF01068.21 CAR22268.1 - 8e-48 162.8 0.1 1.6e-47 161.8 0.0 1.6 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CAR22268.1 - 8.6e-26 91.3 0.0 1.5e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 CAR22268.1 - 3.5e-18 65.8 0.0 1.1e-09 38.6 0.0 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 CAR22268.1 - 1.4e-10 41.7 0.1 3.3e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 CAR22268.1 - 4e-08 33.7 0.0 1.4e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 CAR22268.1 - 9e-08 32.4 0.0 9.6e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.19 CAR22268.1 - 0.0014 18.5 0.3 0.2 11.5 0.3 3.0 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain NPR2 PF06218.11 CAR22269.1 - 5e-134 447.4 0.0 1.4e-132 442.6 0.0 2.1 1 1 0 1 1 1 1 Nitrogen permease regulator 2 ThiD2 PF17792.1 CAR22269.1 - 0.17 12.3 1.3 0.54 10.7 1.3 1.9 1 0 0 1 1 1 0 ThiD2 family Kinesin PF00225.23 CAR22270.1 - 7.4e-97 324.3 4.6 7.4e-97 324.3 4.6 2.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAR22270.1 - 4.3e-21 75.4 8.7 6.6e-20 71.6 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding RasGEF_N_2 PF14663.6 CAR22270.1 - 0.0015 18.9 0.2 0.059 13.8 0.1 3.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Bcl-2_3 PF15286.6 CAR22270.1 - 0.017 15.7 1.6 0.031 14.9 0.3 2.2 3 0 0 3 3 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Spectrin PF00435.21 CAR22270.1 - 0.058 13.9 14.2 0.31 11.5 0.3 4.4 3 1 1 4 4 4 0 Spectrin repeat GreA_GreB_N PF03449.15 CAR22270.1 - 0.095 12.9 4.1 0.13 12.5 0.6 3.1 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Rx_N PF18052.1 CAR22270.1 - 0.66 10.3 3.8 5.6 7.3 0.5 3.7 2 1 1 3 3 3 0 Rx N-terminal domain TPR_MLP1_2 PF07926.12 CAR22270.1 - 0.89 9.6 19.0 0.1 12.7 1.7 4.5 3 2 0 4 4 4 0 TPR/MLP1/MLP2-like protein FliS PF02561.14 CAR22270.1 - 2.3 8.5 9.2 5.7 7.2 0.0 3.9 2 1 2 4 4 4 0 Flagellar protein FliS Laminin_II PF06009.12 CAR22270.1 - 4 7.5 20.2 7.7 6.5 0.3 4.3 2 2 2 5 5 5 0 Laminin Domain II CENP-Q PF13094.6 CAR22270.1 - 5.4 7.2 12.2 11 6.2 7.2 2.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Fcf1 PF04900.12 CAR22271.1 - 2.9e-35 120.6 0.6 4.4e-35 120.0 0.6 1.3 1 0 0 1 1 1 1 Fcf1 PHC2_SAM_assoc PF16616.5 CAR22271.1 - 3 8.7 10.6 0.75 10.6 6.9 2.0 2 1 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Peptidase_S8 PF00082.22 CAR22273.1 - 2.9e-33 115.4 10.0 5.3e-33 114.5 10.0 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CAR22273.1 - 1.8e-09 38.1 0.2 5e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 UPF0184 PF03670.13 CAR22273.1 - 0.11 12.9 0.1 0.36 11.2 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DUF4513 PF14983.6 CAR22273.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4513) AATase PF07247.12 CAR22274.1 - 2.1e-154 514.8 0.0 2.5e-154 514.6 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Lyase_1 PF00206.20 CAR22275.1 - 1.8e-116 388.9 0.0 2.5e-116 388.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CAR22275.1 - 2.6e-24 85.4 0.0 7.3e-24 83.9 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus Mating_N PF12731.7 CAR22275.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Mating-type protein beta 1 Mitochondr_Som1 PF11093.8 CAR22276.1 - 5.3e-14 52.0 0.2 2.1e-13 50.1 0.2 1.8 1 1 0 1 1 1 1 Mitochondrial export protein Som1 zf-C5HC2 PF02928.16 CAR22276.1 - 0.06 13.8 0.1 0.078 13.4 0.1 1.2 1 0 0 1 1 1 0 C5HC2 zinc finger PGM_PMM_I PF02878.16 CAR22277.1 - 2.5e-15 56.4 0.0 4.7e-09 36.1 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CAR22277.1 - 7.2e-11 42.1 0.3 1.7e-10 40.9 0.3 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 CAR22277.1 - 0.0012 19.5 0.1 0.0096 16.5 0.1 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CAR22277.1 - 0.0015 18.7 0.1 0.0038 17.4 0.1 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Kelch_4 PF13418.6 CAR22278.1 - 3.7e-33 113.3 7.6 3.8e-08 33.2 0.2 7.2 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CAR22278.1 - 1.1e-29 102.1 7.7 2.4e-09 37.2 0.0 6.6 7 0 0 7 7 7 3 Galactose oxidase, central domain DUF4110 PF13422.6 CAR22278.1 - 1.5e-25 89.1 0.7 1.5e-25 89.1 0.7 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 CAR22278.1 - 1.9e-16 59.7 15.2 0.00015 22.0 0.1 6.9 6 1 1 7 7 7 5 Kelch motif Kelch_5 PF13854.6 CAR22278.1 - 4.8e-12 45.6 2.6 0.42 10.6 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CAR22278.1 - 2.5e-08 33.4 8.8 0.046 13.3 0.2 5.6 5 1 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CAR22278.1 - 2.5e-08 33.6 12.3 0.51 10.4 0.0 6.4 6 0 0 6 6 6 4 Kelch motif CAF1C_H4-bd PF12265.8 CAR22279.1 - 6.2e-24 84.0 1.5 1.1e-23 83.3 0.5 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CAR22279.1 - 4.9e-20 71.5 3.3 3.3e-06 27.7 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22279.1 - 0.0058 16.9 0.0 2.3 8.6 0.0 3.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AATase PF07247.12 CAR22280.1 - 6.5e-06 25.0 1.4 6.5e-06 25.0 1.4 2.8 2 1 0 2 2 2 1 Alcohol acetyltransferase PLN_propep PF16485.5 CAR22280.1 - 0.027 14.2 0.1 0.091 12.5 0.1 1.8 2 0 0 2 2 2 0 Protealysin propeptide DNA_pol_phi PF04931.13 CAR22281.1 - 7.8e-217 722.0 22.1 1e-216 721.6 22.1 1.2 1 0 0 1 1 1 1 DNA polymerase phi RRN3 PF05327.11 CAR22281.1 - 2 6.9 10.7 14 4.1 7.8 2.6 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ABC_membrane PF00664.23 CAR22282.1 - 6e-56 190.1 5.5 7.8e-56 189.7 5.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CAR22282.1 - 6.8e-33 114.1 0.7 2e-32 112.6 0.0 2.2 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 CAR22282.1 - 1.8e-05 24.3 0.0 0.0066 15.9 0.0 3.1 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAR22282.1 - 0.0031 17.9 0.0 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CAR22282.1 - 0.0034 17.8 0.0 0.042 14.3 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CAR22282.1 - 0.0076 16.0 0.0 0.24 11.1 0.0 2.8 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.6 CAR22282.1 - 0.014 15.6 0.0 0.15 12.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAR22282.1 - 0.015 15.0 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CAR22282.1 - 0.032 14.2 0.1 0.25 11.4 0.0 2.3 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CAR22282.1 - 0.065 12.9 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CAR22282.1 - 0.14 12.3 0.4 11 6.1 0.0 3.0 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 CAR22282.1 - 0.17 11.4 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region KAR9 PF08580.10 CAR22283.1 - 2.1e-28 99.3 6.5 3.2e-28 98.7 6.5 1.4 1 1 0 1 1 1 1 Yeast cortical protein KAR9 HeLo PF14479.6 CAR22283.1 - 0.019 14.8 0.8 0.039 13.8 0.3 1.8 2 0 0 2 2 2 0 Prion-inhibition and propagation Peptidase_M3_N PF08439.10 CAR22283.1 - 0.18 12.1 1.7 2.7 8.3 0.1 2.9 2 0 0 2 2 2 0 Oligopeptidase F PI-PLC-X PF00388.19 CAR22284.1 - 3e-48 163.1 0.0 8.1e-48 161.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CAR22284.1 - 2.5e-40 137.4 0.1 1e-39 135.4 0.1 2.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CAR22284.1 - 2.3e-07 31.2 1.4 1.1e-06 29.0 0.2 2.6 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 CAR22284.1 - 7.1e-05 22.1 0.0 0.00021 20.6 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_10 PF14788.6 CAR22284.1 - 8.5e-05 22.3 0.4 0.00023 21.0 0.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CAR22284.1 - 0.00028 21.3 0.9 0.0083 16.6 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair C2 PF00168.30 CAR22284.1 - 0.0036 17.6 0.0 0.011 16.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 CAR22284.1 - 0.0043 16.9 0.1 0.02 14.8 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CAR22284.1 - 0.0085 15.5 0.1 0.027 13.9 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CAR22284.1 - 0.067 13.1 0.2 0.35 10.7 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair GDPD PF03009.17 CAR22284.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family RrnaAD PF00398.20 CAR22286.1 - 1.1e-69 234.4 0.0 1.3e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CAR22286.1 - 4.1e-06 27.4 0.0 1.4e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR22286.1 - 0.00072 20.2 0.0 0.0021 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CAR22286.1 - 0.00086 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 CAR22286.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.20 CAR22286.1 - 0.0069 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CAR22286.1 - 0.037 13.9 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CAR22286.1 - 0.067 13.9 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CAR22286.1 - 0.087 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 CAR22286.1 - 0.15 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase FMN_dh PF01070.18 CAR22287.1 - 1e-116 389.8 0.0 1.3e-116 389.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CAR22287.1 - 8.7e-21 73.9 0.0 2.2e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CAR22287.1 - 5.2e-08 32.4 0.5 2.2e-07 30.4 0.1 2.1 2 1 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 CAR22287.1 - 3.1e-06 26.8 0.0 4.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CAR22287.1 - 2.4e-05 23.5 1.2 0.0059 15.7 0.0 3.0 2 1 1 3 3 3 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CAR22287.1 - 0.087 12.3 0.5 14 5.0 0.0 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein DUF561 PF04481.12 CAR22287.1 - 0.13 11.4 0.1 0.32 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Dus PF01207.17 CAR22287.1 - 0.14 11.3 0.0 0.32 10.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) ThiG PF05690.14 CAR22287.1 - 0.17 11.1 0.1 7.1 5.9 0.1 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Aminotran_3 PF00202.21 CAR22288.1 - 8.2e-61 205.9 0.0 9.5e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CAR22288.1 - 0.03 13.5 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II FMN_dh PF01070.18 CAR22289.1 - 6.4e-94 314.8 0.0 1.5e-93 313.6 0.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CAR22289.1 - 5.6e-23 80.9 0.0 1.5e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CAR22289.1 - 1.1e-09 37.9 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CAR22289.1 - 0.00011 21.3 0.1 0.00049 19.2 0.1 1.9 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CAR22289.1 - 0.013 15.0 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Glu_syn_central PF04898.14 CAR22289.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Glutamate synthase central domain Ribonuc_L-PSP PF01042.21 CAR22290.1 - 1.3e-19 70.4 0.0 1.5e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ApbA_C PF08546.11 CAR22291.1 - 2e-29 102.3 0.0 7.4e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CAR22291.1 - 7.3e-28 97.1 0.0 1.2e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Flocculin PF00624.18 CAR22292.1 - 6.2e-66 218.4 176.4 2.1e-14 53.5 18.4 10.9 10 2 1 11 11 11 7 Flocculin repeat Amidohydro_1 PF01979.20 CAR22294.1 - 9.6e-37 127.1 0.1 1.2e-36 126.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR22294.1 - 1.8e-12 47.5 0.0 3.3e-06 26.8 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family MFS_1 PF07690.16 CAR22295.1 - 1.2e-09 37.6 54.3 2.2e-07 30.1 53.2 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR22295.1 - 1.1e-05 24.5 12.0 1.1e-05 24.5 12.0 3.7 4 1 1 5 5 5 1 Sugar (and other) transporter Sir1 PF11603.8 CAR22296.1 - 2e-30 105.7 0.1 5.9e-30 104.2 0.1 1.9 1 0 0 1 1 1 1 Regulatory protein Sir1 Helicase_C PF00271.31 CAR22296.1 - 2.1e-12 47.4 0.0 6.3e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR22296.1 - 8.4e-07 28.9 0.0 3.9e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase His_Phos_2 PF00328.22 CAR22297.1 - 1e-45 156.8 0.0 1.5e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1349 PF07081.11 CAR22298.1 - 1.7e-63 213.5 0.2 1.9e-63 213.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) GH43_C2 PF17851.1 CAR22298.1 - 4.5e-06 26.5 0.0 5.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PFU PF09070.11 CAR22298.1 - 0.041 14.1 0.0 0.067 13.5 0.0 1.3 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Pepdidase_M14_N PF18027.1 CAR22298.1 - 0.055 13.8 0.2 0.11 12.9 0.1 1.5 1 1 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain DUP PF00674.18 CAR22299.1 - 4.8e-18 65.2 0.6 4.8e-18 65.2 0.6 2.2 2 1 1 3 3 3 1 DUP family LURAP PF14854.6 CAR22299.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Leucine rich adaptor protein Transp_cyt_pur PF02133.15 CAR22300.1 - 9e-77 258.7 40.7 1.1e-76 258.5 40.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HRXXH PF13933.6 CAR22301.1 - 1.4e-77 260.6 0.0 1.7e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 CAR22301.1 - 7.3e-06 26.6 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase MF_alpha_N PF05436.11 CAR22301.1 - 0.18 11.7 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus DUP PF00674.18 CAR22302.1 - 1.2e-26 92.8 0.4 7.3e-16 58.2 0.1 2.6 2 0 0 2 2 2 2 DUP family MFS_1 PF07690.16 CAR22303.1 - 2.3e-30 105.7 33.6 2.3e-30 105.7 33.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR22303.1 - 0.14 11.0 38.9 0.015 14.2 7.0 3.4 2 2 0 3 3 3 0 Sugar (and other) transporter TPP_enzyme_N PF02776.18 CAR22304.1 - 1.8e-36 125.4 0.0 2.2e-35 121.8 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CAR22304.1 - 8.2e-22 77.6 0.2 2.7e-20 72.7 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR22304.1 - 1.2e-21 76.9 0.0 2.8e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Ldh_1_N PF00056.23 CAR22305.1 - 3.3e-43 147.2 1.2 4.8e-43 146.6 1.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAR22305.1 - 2.3e-24 86.2 0.0 4.1e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ThiF PF00899.21 CAR22305.1 - 0.00046 19.6 0.2 0.0024 17.2 0.1 1.9 2 0 0 2 2 2 1 ThiF family Glyco_hydro_4 PF02056.16 CAR22305.1 - 0.00071 19.2 0.3 0.009 15.6 0.0 2.5 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase DAO PF01266.24 CAR22305.1 - 0.0035 17.0 0.6 0.0063 16.1 0.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CAR22305.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 CAR22305.1 - 0.0063 16.1 0.8 0.0063 16.1 0.8 2.3 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CAR22305.1 - 0.0081 16.4 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CAR22305.1 - 0.01 15.1 1.2 0.02 14.2 1.2 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Csm4_C PF17953.1 CAR22305.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain TrkA_N PF02254.18 CAR22305.1 - 0.012 15.8 0.3 0.05 13.9 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 CAR22305.1 - 0.049 13.5 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CAR22305.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CAR22305.1 - 0.069 12.8 0.2 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Glyco_trans_4_2 PF13477.6 CAR22305.1 - 0.12 12.4 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like Sugar_tr PF00083.24 CAR22306.1 - 2e-132 442.3 23.1 2.3e-132 442.1 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR22306.1 - 1.9e-20 73.1 34.8 3.6e-17 62.3 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 CAR22306.1 - 1.4 9.2 13.3 0.037 14.2 5.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) MFS_1 PF07690.16 CAR22307.1 - 3.5e-10 39.3 39.2 1.4e-09 37.4 39.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR22307.1 - 0.01 14.3 28.3 0.023 13.1 28.3 1.7 1 1 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) Cwf_Cwc_15 PF04889.12 CAR22308.1 - 0.022 14.5 6.8 0.033 13.9 6.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 CAR22308.1 - 0.048 13.0 8.8 0.055 12.8 8.8 1.1 1 0 0 1 1 1 0 BUD22 Rad4 PF03835.15 CAR22308.1 - 0.072 12.8 0.0 0.072 12.8 0.0 1.7 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain SDA1 PF05285.12 CAR22308.1 - 0.076 12.4 7.5 0.099 12.0 7.5 1.2 1 0 0 1 1 1 0 SDA1 DUF434 PF04256.12 CAR22308.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF434) Nop14 PF04147.12 CAR22308.1 - 0.74 7.9 8.0 0.83 7.8 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family ELFV_dehydrog PF00208.21 CAR22309.1 - 4.5e-83 278.7 5.1 5.6e-83 278.4 5.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CAR22309.1 - 1.6e-46 157.4 0.0 8.2e-46 155.1 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Sugar_tr PF00083.24 CAR22310.1 - 1.9e-101 340.2 22.2 2.2e-101 340.0 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR22310.1 - 3.4e-20 72.3 30.5 3.7e-19 68.9 20.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CAR22310.1 - 0.0025 16.4 3.3 0.0025 16.4 3.3 3.5 3 1 1 4 4 4 1 MFS/sugar transport protein Saf_2TM PF18303.1 CAR22310.1 - 0.061 12.9 0.6 1.8 8.2 0.4 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Fungal_trans_2 PF11951.8 CAR22311.1 - 5e-09 35.5 0.8 4.8e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22311.1 - 4.6e-08 33.0 8.2 9.9e-08 32.0 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 CAR22311.1 - 0.69 10.4 7.8 1.9 9.1 7.8 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region ADH_N PF08240.12 CAR22312.1 - 3.5e-30 104.1 6.8 7.2e-30 103.1 6.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR22312.1 - 1.5e-19 70.3 0.0 2.5e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CAR22312.1 - 2.3e-12 46.8 0.0 3.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 CAR22312.1 - 0.017 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CAR22312.1 - 0.071 12.3 0.6 0.14 11.4 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Hexapep PF00132.24 CAR22312.1 - 0.072 12.8 0.9 0.19 11.5 0.9 1.8 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) ADH_zinc_N_2 PF13602.6 CAR22312.1 - 0.098 13.7 0.0 0.34 12.0 0.0 1.8 1 1 1 2 2 2 0 Zinc-binding dehydrogenase DUF5420 PF17457.2 CAR22312.1 - 0.11 12.4 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5420) Alb1 PF09135.11 CAR22313.1 - 1.4e-23 83.8 12.0 1.4e-23 83.8 12.0 1.7 2 0 0 2 2 2 1 Alb1 Cation_ATPase_C PF00689.21 CAR22314.1 - 0.026 14.2 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Aldedh PF00171.22 CAR22315.1 - 1.2e-182 607.6 1.3 1.3e-182 607.4 1.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family VCPO_N PF17897.1 CAR22315.1 - 0.073 12.9 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain LRR_4 PF12799.7 CAR22316.1 - 2.3e-13 50.1 28.0 2.1e-05 24.8 2.4 7.8 4 1 5 9 9 9 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR22316.1 - 3.3e-13 49.2 25.0 0.00011 21.8 0.1 6.6 4 1 3 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 CAR22316.1 - 1.3e-05 24.8 19.3 0.0097 15.9 0.1 7.9 10 0 0 10 10 10 1 Leucine Rich repeat LRR_1 PF00560.33 CAR22316.1 - 0.00091 19.5 25.3 1.1 10.1 0.0 9.0 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 CAR22316.1 - 0.0015 18.1 6.1 1.6 8.2 0.1 4.2 3 1 0 5 5 5 2 Leucine-rich repeat RNR_inhib PF08591.10 CAR22316.1 - 0.061 14.6 2.1 0.092 14.1 0.5 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor Kelch_3 PF13415.6 CAR22318.1 - 6.4e-09 35.9 0.7 0.0011 19.1 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CAR22318.1 - 4.2e-06 26.7 5.7 0.0065 16.5 0.3 5.6 6 0 0 6 6 6 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CAR22318.1 - 0.00037 20.4 6.3 13 5.9 0.1 6.0 6 1 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 CAR22318.1 - 0.0031 17.7 5.9 1.2 9.5 0.1 5.4 5 1 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 CAR22318.1 - 0.01 15.4 6.2 0.2 11.3 0.1 5.0 7 0 0 7 7 7 0 Kelch motif Kelch_2 PF07646.15 CAR22318.1 - 0.29 11.2 6.2 1.4 9.0 0.5 4.6 6 0 0 6 6 6 0 Kelch motif GDI PF00996.18 CAR22319.1 - 2.1e-44 151.7 0.0 3.8e-44 150.9 0.0 1.3 1 1 0 1 1 1 1 GDP dissociation inhibitor UDPG_MGDP_dh_N PF03721.14 CAR22319.1 - 0.11 12.1 0.1 0.31 10.6 0.1 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1749 PF08538.10 CAR22319.1 - 0.11 11.5 0.2 0.22 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Ribosomal_L7Ae PF01248.26 CAR22320.1 - 1.3e-22 79.3 0.2 1.8e-22 78.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.12 CAR22320.1 - 0.085 13.2 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) Rad1 PF02144.16 CAR22321.1 - 1.2e-64 218.1 0.8 1.4e-64 217.8 0.8 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 CH PF00307.31 CAR22322.1 - 4.2e-14 52.6 0.0 5.6e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain TRP PF06011.12 CAR22323.1 - 5.5e-156 519.6 31.7 8.1e-156 519.0 31.7 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CAR22323.1 - 9.7e-41 139.4 2.5 1.6e-40 138.7 2.5 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CAR22323.1 - 8e-06 26.3 0.1 1.5e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 ML domain AGTRAP PF06396.11 CAR22323.1 - 1 9.2 9.1 0.57 10.0 0.2 3.3 3 0 0 3 3 3 0 Angiotensin II, type I receptor-associated protein (AGTRAP) EF_assoc_1 PF08355.12 CAR22324.1 - 4e-26 90.4 1.0 7.4e-26 89.6 1.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 CAR22324.1 - 5.9e-26 90.3 0.0 1.7e-25 88.8 0.0 1.9 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 CAR22324.1 - 1.5e-24 86.4 0.0 1.5e-10 40.9 0.0 3.3 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CAR22324.1 - 1.7e-14 54.1 0.0 0.00073 19.7 0.0 3.5 3 0 0 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 CAR22324.1 - 3.6e-07 29.3 4.3 0.017 14.6 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CAR22324.1 - 0.00011 21.8 4.2 0.11 12.5 0.5 3.1 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.23 CAR22324.1 - 0.00013 22.0 0.0 0.44 10.7 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CAR22324.1 - 0.00015 21.9 0.0 0.029 14.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family EF-hand_7 PF13499.6 CAR22324.1 - 0.00032 21.1 1.3 0.28 11.7 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair Arf PF00025.21 CAR22324.1 - 0.00058 19.4 0.0 0.67 9.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_24 PF13479.6 CAR22324.1 - 0.0038 17.0 0.0 0.94 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CAR22324.1 - 0.0054 16.3 0.0 7.5 6.0 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CAR22324.1 - 0.0065 16.9 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Septin PF00735.18 CAR22324.1 - 0.011 15.1 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 CAR22324.1 - 0.021 15.1 0.0 0.67 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CAR22324.1 - 0.049 13.5 0.1 0.81 9.6 0.0 2.7 2 1 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 CAR22324.1 - 0.092 12.7 0.1 3.6 7.5 0.0 3.1 3 1 1 4 4 4 0 NACHT domain STAR_dimer PF16544.5 CAR22324.1 - 0.14 11.7 0.2 0.32 10.6 0.2 1.6 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein EF-hand_8 PF13833.6 CAR22324.1 - 0.16 11.9 0.5 13 5.7 0.3 3.0 2 0 0 2 2 2 0 EF-hand domain pair AAA_18 PF13238.6 CAR22324.1 - 0.19 12.3 0.0 3 8.4 0.0 2.8 2 1 1 3 3 3 0 AAA domain EF-hand_5 PF13202.6 CAR22324.1 - 0.35 10.4 8.2 1.9 8.1 0.9 3.2 3 0 0 3 3 3 0 EF hand Proteasome PF00227.26 CAR22325.1 - 5.4e-52 176.0 0.0 6.7e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR22325.1 - 5.2e-12 45.2 1.0 5.8e-12 45.1 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Mto2_bdg PF12808.7 CAR22326.1 - 0.00013 22.2 4.9 0.00013 22.2 4.9 4.4 4 1 0 4 4 4 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4094 PF13334.6 CAR22326.1 - 0.0085 16.5 3.2 0.0085 16.5 3.2 4.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4094) Bcr-Abl_Oligo PF09036.10 CAR22326.1 - 0.6 10.2 0.0 0.6 10.2 0.0 4.4 5 0 0 5 5 5 0 Bcr-Abl oncoprotein oligomerisation domain ACP_PD PF04336.12 CAR22326.1 - 1.1 9.7 4.7 36 4.9 0.2 3.9 2 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase DUF730 PF05325.11 CAR22326.1 - 1.5 8.9 5.2 8 6.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF730) DUF1664 PF07889.12 CAR22326.1 - 2.8 8.0 32.9 0.63 10.1 0.9 6.1 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) ROS_MUCR PF05443.11 CAR22326.1 - 3.5 7.7 6.2 4.6 7.3 2.8 3.0 2 2 0 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF948 PF06103.11 CAR22326.1 - 5.3 7.4 13.2 17 5.8 0.1 4.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 CAR22326.1 - 9.6 6.8 33.4 0.78 10.3 4.8 6.4 5 1 2 7 7 7 0 Syntaxin 6, N-terminal eIF2A PF08662.11 CAR22327.1 - 4.3e-27 95.3 1.2 4.2e-23 82.2 0.5 3.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CAR22327.1 - 1.4e-12 47.3 0.0 3.5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BolA PF01722.18 CAR22328.1 - 2.1e-13 50.4 0.0 7e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein BolA PF01722.18 CAR22329.1 - 2.3e-26 91.9 0.3 2.9e-26 91.5 0.3 1.2 1 0 0 1 1 1 1 BolA-like protein GCV_H PF01597.19 CAR22330.1 - 1.8e-44 150.6 0.2 2.1e-44 150.3 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein PDEase_I PF00233.19 CAR22331.1 - 9.9e-54 182.6 0.2 1.4e-53 182.1 0.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CAR22331.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 HD domain S_100 PF01023.19 CAR22331.1 - 0.027 14.2 0.1 0.072 12.8 0.1 1.7 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain SAM_2 PF07647.17 CAR22332.1 - 7.2e-10 38.8 0.0 2.7e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CAR22332.1 - 1.2e-05 25.7 0.0 3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3453 PF11935.8 CAR22333.1 - 4.1e-53 180.3 0.0 3.9e-52 177.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Ribosomal_S9 PF00380.19 CAR22333.1 - 0.065 13.7 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S9/S16 Histone PF00125.24 CAR22334.1 - 1.8e-23 83.4 0.0 2.2e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR22334.1 - 2.5e-22 78.9 1.7 3.3e-22 78.6 1.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-X PF09415.10 CAR22334.1 - 0.015 15.6 0.1 0.022 15.1 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X TAFII28 PF04719.14 CAR22334.1 - 0.027 14.6 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region PX PF00787.24 CAR22335.1 - 4.6e-21 74.9 0.1 6.7e-21 74.4 0.1 1.2 1 0 0 1 1 1 1 PX domain COPIIcoated_ERV PF07970.12 CAR22336.1 - 3e-79 266.0 0.8 3.6e-79 265.7 0.8 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAR22336.1 - 2.1e-27 95.3 0.0 6.8e-27 93.7 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CDC24 PF06395.11 CAR22337.1 - 3.2e-37 126.7 0.9 8.2e-37 125.3 0.9 1.8 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 CAR22337.1 - 1.6e-32 113.2 0.9 1.6e-32 113.2 0.9 2.5 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 CAR22337.1 - 9e-30 103.5 0.2 2.3e-29 102.1 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 CAR22337.1 - 8.7e-06 25.6 0.3 3.5e-05 23.7 0.3 2.1 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 CAR22337.1 - 0.038 14.5 1.5 0.099 13.2 0.1 2.5 2 2 0 2 2 2 0 PH domain ETF_QO PF05187.13 CAR22338.1 - 3.3e-44 149.3 0.3 5.5e-44 148.6 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CAR22338.1 - 3e-09 37.0 0.0 0.00019 21.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CAR22338.1 - 1.1e-07 31.3 0.2 0.0059 15.7 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CAR22338.1 - 2.5e-05 23.6 0.1 0.00093 18.5 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR22338.1 - 2.7e-05 24.3 0.1 0.00011 22.4 0.0 2.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAR22338.1 - 4.7e-05 22.7 0.0 0.022 14.0 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 CAR22338.1 - 0.00014 20.7 0.2 0.013 14.2 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 CAR22338.1 - 0.0019 17.5 0.3 0.016 14.5 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 CAR22338.1 - 0.0062 15.8 0.3 0.017 14.4 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CAR22338.1 - 0.011 14.8 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 CAR22338.1 - 0.012 16.2 0.6 2.5 8.7 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR22338.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CAR22338.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CAR22338.1 - 0.14 11.0 0.2 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Big_9 PF17963.1 CAR22339.1 - 0.056 14.2 1.0 0.16 12.7 1.0 1.8 1 0 0 1 1 1 0 Bacterial Ig domain Cadherin_4 PF17803.1 CAR22339.1 - 0.43 11.2 4.0 0.18 12.5 1.1 1.8 2 0 0 2 2 2 0 Bacterial cadherin-like domain Cupin_8 PF13621.6 CAR22340.1 - 5.2e-42 144.3 0.0 1.3e-40 139.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CAR22340.1 - 0.0029 17.1 0.0 0.061 12.8 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein Cyclin_N PF00134.23 CAR22341.1 - 1.9e-27 95.5 0.2 3.8e-27 94.6 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR22341.1 - 0.026 14.6 0.3 0.08 13.0 0.3 1.8 1 0 0 1 1 1 0 Cyclin, C-terminal domain PPR PF01535.20 CAR22342.1 - 0.0041 17.3 0.4 3.3 8.1 0.0 4.1 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 CAR22342.1 - 0.033 14.4 0.5 12 6.1 0.0 4.2 4 0 0 4 4 4 0 PPR repeat family PPR_3 PF13812.6 CAR22342.1 - 0.1 12.7 0.2 59 3.8 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Ribosomal_L17 PF01196.19 CAR22342.1 - 0.32 11.9 1.5 4.1 8.4 0.1 3.4 2 1 1 3 3 3 0 Ribosomal protein L17 Cyto_heme_lyase PF01265.17 CAR22343.1 - 5.7e-99 331.4 3.2 2.1e-98 329.5 3.2 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SOG2 PF10428.9 CAR22344.1 - 4.2e-122 408.9 20.8 4.2e-122 408.9 20.8 2.3 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.6 CAR22344.1 - 5.9e-15 54.8 8.9 5e-07 29.4 0.2 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CAR22344.1 - 2.1e-13 50.2 8.3 2e-06 28.0 0.2 4.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAR22344.1 - 0.001 18.6 3.0 0.0027 17.2 0.3 2.5 2 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CAR22344.1 - 0.0018 18.6 5.8 5.7 7.9 0.0 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat TTRAP PF14203.6 CAR22344.1 - 0.0086 16.0 0.1 0.034 14.1 0.1 2.1 2 0 0 2 2 2 1 Putative tranposon-transfer assisting protein Collagen_mid PF15984.5 CAR22344.1 - 0.044 13.5 0.6 0.11 12.3 0.6 1.6 1 0 0 1 1 1 0 Bacterial collagen, middle region SpecificRecomb PF10136.9 CAR22344.1 - 0.068 11.5 2.2 0.071 11.4 0.5 1.8 2 0 0 2 2 2 0 Site-specific recombinase LRR_6 PF13516.6 CAR22344.1 - 0.73 10.0 5.8 13 6.2 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat TFB6 PF17110.5 CAR22345.1 - 7.1e-34 117.0 0.0 2.4e-29 102.3 0.0 2.8 2 1 1 3 3 3 2 Subunit 11 of the general transcription factor TFIIH Pkinase PF00069.25 CAR22346.1 - 1.9e-53 181.5 0.0 3.1e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22346.1 - 2.4e-29 102.4 0.0 3.8e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CAR22346.1 - 1.3e-13 51.0 0.2 1.8e-12 47.4 0.0 2.4 2 0 0 2 2 2 1 FHA domain Pkinase_fungal PF17667.1 CAR22346.1 - 1.8e-06 27.0 0.0 6.3e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CAR22346.1 - 0.00017 21.0 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR22346.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAR22346.1 - 0.01 14.8 0.1 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Haspin like kinase domain MNE1 PF13762.6 CAR22347.1 - 4.4e-49 166.3 3.4 1.2e-48 164.9 3.4 1.8 1 0 0 1 1 1 1 Mitochondrial splicing apparatus component Aminotran_5 PF00266.19 CAR22349.1 - 6.8e-16 58.2 0.0 8.9e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CAR22349.1 - 4e-05 22.9 0.0 6.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CAR22349.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AA_permease PF00324.21 CAR22350.1 - 1.1e-136 456.3 38.6 1.2e-136 456.1 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR22350.1 - 2.9e-26 92.3 41.9 4.5e-26 91.7 41.9 1.2 1 0 0 1 1 1 1 Amino acid permease NCE101 PF11654.8 CAR22350.1 - 0.075 12.7 3.6 0.3 10.8 0.5 2.8 2 0 0 2 2 2 0 Non-classical export protein 1 Adeno_E3B PF03376.14 CAR22350.1 - 4.7 7.5 7.6 2.5 8.4 0.0 3.1 3 0 0 3 3 3 0 Adenovirus E3B protein PK PF00224.21 CAR22351.1 - 1.8e-170 566.4 1.2 2.2e-170 566.1 1.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CAR22351.1 - 6.8e-33 113.4 0.0 1.9e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CAR22351.1 - 1.2e-05 24.6 0.3 3e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Peripla_BP_1 PF00532.21 CAR22351.1 - 0.13 11.6 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family IMS PF00817.20 CAR22352.1 - 9.7e-31 106.8 0.0 2.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 CAR22352.1 - 3.3e-11 43.4 0.0 7.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 CAR22352.1 - 6.6e-10 39.7 0.0 3.8e-09 37.3 0.0 2.2 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT PF00533.26 CAR22352.1 - 2.7e-09 37.3 0.1 8.7e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CAR22352.1 - 9.6e-07 29.0 0.1 1e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain REV1_C PF16727.5 CAR22352.1 - 1.4e-05 25.3 0.0 3.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain IMS_HHH PF11798.8 CAR22352.1 - 0.0022 18.2 0.0 0.008 16.5 0.0 2.0 2 0 0 2 2 2 1 IMS family HHH motif PTCB-BRCT PF12738.7 CAR22352.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain mCpol PF18182.1 CAR22352.1 - 0.034 14.5 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 minimal CRISPR polymerase domain FLYWCH_u PF16662.5 CAR22352.1 - 0.1 12.7 0.0 0.33 11.0 0.0 1.8 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein 1 HLH PF00010.26 CAR22353.1 - 1.1e-19 70.1 0.1 1.1e-19 70.1 0.1 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Prenyltrans PF00432.21 CAR22353.1 - 0.03 14.1 3.4 12 5.8 0.0 4.1 4 0 0 4 4 4 0 Prenyltransferase and squalene oxidase repeat Med3 PF11593.8 CAR22353.1 - 0.38 9.9 4.2 0.75 8.9 4.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CbiG_N PF11760.8 CAR22354.1 - 0.018 15.0 0.0 0.25 11.4 0.0 2.2 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal S6PP PF05116.13 CAR22354.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase PT-VENN PF04829.13 CAR22354.1 - 0.38 10.9 3.4 1.6 8.9 3.4 2.0 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif MMR_HSR1_Xtn PF16897.5 CAR22355.1 - 6e-37 125.9 0.0 1.4e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CAR22355.1 - 6.5e-22 77.3 0.0 1.2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CAR22355.1 - 1.8e-19 69.9 0.0 4.9e-19 68.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR22355.1 - 1e-08 34.9 0.0 2.6e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CAR22355.1 - 0.0081 16.2 0.2 6.4 6.8 0.2 2.5 1 1 0 2 2 2 2 Dynamin family MeaB PF03308.16 CAR22355.1 - 0.011 14.8 0.1 0.025 13.6 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CAR22355.1 - 0.025 14.9 0.1 11 6.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 CAR22356.1 - 1.5e-34 119.3 0.0 1.5e-34 119.3 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CAR22356.1 - 2.5e-21 75.8 0.0 8.5e-21 74.1 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CAR22356.1 - 1.1e-14 54.6 3.3 6.9e-10 39.2 0.0 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CAR22356.1 - 3.4e-06 26.9 0.1 1.2e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 CAR22356.1 - 5.8e-06 26.4 0.0 5.8e-06 26.4 0.0 3.8 5 0 0 5 5 5 1 50S ribosome-binding GTPase Roc PF08477.13 CAR22356.1 - 0.00068 19.9 0.0 0.00068 19.9 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CAR22356.1 - 0.0058 16.2 0.0 0.048 13.2 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CAR22356.1 - 0.072 12.9 2.9 0.072 12.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_pol_Rpb1_5 PF04998.17 CAR22357.1 - 5.8e-97 324.3 0.5 5.8e-97 324.3 0.5 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CAR22357.1 - 1.3e-70 236.9 0.1 2.9e-70 235.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CAR22357.1 - 5.6e-41 140.1 0.2 1.1e-38 132.7 0.0 3.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CAR22357.1 - 6.7e-27 94.6 0.8 1.3e-25 90.4 0.0 3.3 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CAR22357.1 - 2.5e-24 85.3 0.1 1.5e-23 82.8 0.1 2.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rick_17kDa_Anti PF05433.15 CAR22358.1 - 0.28 11.1 10.7 0.56 10.1 10.5 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain Fungal_trans PF04082.18 CAR22359.1 - 4.5e-07 29.2 0.0 7.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22359.1 - 0.00028 21.0 9.6 0.00069 19.7 9.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPA43_OB PF17875.1 CAR22360.1 - 4.6e-28 98.3 0.5 2.1e-27 96.2 0.3 2.2 2 1 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CAR22360.1 - 7.9e-13 48.6 0.0 1.5e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mis12 PF05859.12 CAR22361.1 - 6.7e-44 149.2 1.5 1.3e-43 148.3 1.5 1.4 1 0 0 1 1 1 1 Mis12 protein Polo_box_3 PF18544.1 CAR22361.1 - 0.0017 18.9 0.3 0.0068 17.0 0.3 2.0 1 0 0 1 1 1 1 Polo box domain HrpB2 PF09487.10 CAR22361.1 - 0.02 15.3 1.6 0.065 13.7 0.3 2.4 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB2) UQ_con PF00179.26 CAR22362.1 - 1.1e-49 167.7 0.0 1.2e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR22362.1 - 0.002 17.8 0.0 0.0023 17.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CAR22362.1 - 0.01 15.7 0.3 0.021 14.7 0.3 1.4 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CAR22362.1 - 0.016 15.5 0.1 0.027 14.7 0.0 1.5 1 1 0 1 1 1 0 RWD domain SWIRM PF04433.17 CAR22363.1 - 7.5e-09 35.8 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Fungal_trans PF04082.18 CAR22364.1 - 3.3e-33 114.9 0.1 5.5e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22364.1 - 1e-07 31.9 10.8 1.7e-07 31.2 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EntA_Immun PF08951.10 CAR22364.1 - 0.13 12.6 0.0 0.49 10.8 0.0 1.9 2 0 0 2 2 2 0 Enterocin A Immunity Glyco_transf_24 PF18404.1 CAR22365.1 - 1.9e-34 119.3 0.2 3.5e-34 118.5 0.2 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CAR22365.1 - 2.7e-16 60.3 0.6 1.1e-13 51.7 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CAR22365.1 - 9.3e-09 35.3 1.9 2.3e-08 34.0 0.6 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CAR22365.1 - 6.2e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain DUF2507 PF10702.9 CAR22365.1 - 0.013 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) DASH_Dam1 PF08653.10 CAR22365.1 - 0.031 14.1 0.2 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 Stealth_CR2 PF11380.8 CAR22365.1 - 0.067 13.4 0.1 0.26 11.5 0.1 2.0 1 0 0 1 1 1 0 Stealth protein CR2, conserved region 2 tRNA-synt_2c PF01411.19 CAR22366.1 - 3.5e-226 752.0 0.7 5.5e-226 751.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CAR22366.1 - 3.7e-19 68.6 0.2 9e-19 67.3 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CAR22366.1 - 4.4e-13 49.8 3.6 9.2e-13 48.8 3.6 1.6 1 0 0 1 1 1 1 DHHA1 domain RNase_P_Rpp14 PF01900.19 CAR22367.1 - 2.8e-33 114.2 0.2 3.6e-33 113.9 0.2 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family SKIP_SNW PF02731.15 CAR22368.1 - 1.9e-52 177.2 5.4 1.9e-52 177.2 5.4 2.3 2 0 0 2 2 2 2 SKIP/SNW domain NUDIX PF00293.28 CAR22368.1 - 0.034 14.2 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 NUDIX domain CorA PF01544.18 CAR22370.1 - 1.1e-09 38.0 1.3 1.5e-09 37.6 1.3 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein vATP-synt_E PF01991.18 CAR22371.1 - 4.7e-58 195.9 19.4 5.4e-58 195.7 19.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Meckelin PF09773.9 CAR22371.1 - 0.023 12.8 7.1 0.028 12.5 7.1 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Phlebovirus_NSM PF07246.11 CAR22371.1 - 0.054 12.9 12.2 0.075 12.4 12.2 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M E2F_CC-MB PF16421.5 CAR22371.1 - 0.41 11.0 5.5 0.11 12.8 0.6 2.5 2 2 0 2 2 2 0 E2F transcription factor CC-MB domain Exonuc_VII_L PF02601.15 CAR22371.1 - 1.1 8.8 8.4 1.3 8.5 8.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CarD_CdnL_TRCF PF02559.16 CAR22371.1 - 5 7.9 6.7 3.6 8.4 2.0 2.3 1 1 1 2 2 2 0 CarD-like/TRCF domain DNApol_Exo PF18136.1 CAR22372.1 - 1.9e-100 335.6 0.0 3.6e-100 334.8 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CAR22372.1 - 1.4e-50 172.4 0.0 3.3e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family A DUF2040 PF09745.9 CAR22373.1 - 0.00091 19.3 7.6 0.00091 19.3 7.6 2.2 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Glu-tRNAGln PF02686.15 CAR22374.1 - 0.13 12.6 0.0 1.9 8.9 0.0 2.6 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit Synaptobrevin PF00957.21 CAR22375.1 - 2.6e-31 107.2 1.1 3e-31 107.1 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin UPF0258 PF06789.12 CAR22375.1 - 0.092 12.9 0.9 0.14 12.3 0.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) Myosin_head PF00063.21 CAR22376.1 - 1.7e-281 935.3 11.6 1.7e-281 935.3 11.6 2.0 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.19 CAR22376.1 - 3.5e-25 88.3 1.3 3.5e-25 88.3 1.3 3.2 2 1 1 3 3 3 1 DIL domain IQ PF00612.27 CAR22376.1 - 5.8e-06 25.7 20.7 0.2 11.6 0.0 6.5 7 0 0 7 7 6 3 IQ calmodulin-binding motif TPR_MLP1_2 PF07926.12 CAR22376.1 - 0.0001 22.4 13.8 0.0001 22.4 13.8 3.4 1 1 0 2 2 1 1 TPR/MLP1/MLP2-like protein HOOK PF05622.12 CAR22376.1 - 0.00069 17.9 27.8 0.0016 16.7 27.8 1.5 1 0 0 1 1 1 1 HOOK protein AAA_22 PF13401.6 CAR22376.1 - 0.00088 19.6 1.5 0.002 18.4 0.0 2.5 2 0 0 2 2 1 1 AAA domain Myosin_N PF02736.19 CAR22376.1 - 0.00095 18.9 0.1 0.0027 17.5 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain NB-ARC PF00931.22 CAR22376.1 - 0.0031 16.7 1.9 0.0064 15.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain WEMBL PF05701.11 CAR22376.1 - 0.007 15.1 32.4 0.016 13.9 32.2 1.6 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.11 CAR22376.1 - 0.014 14.3 33.7 0.017 14.0 31.4 2.2 1 1 0 1 1 1 0 Spc7 kinetochore protein Mg_chelatase PF01078.21 CAR22376.1 - 0.075 12.4 0.1 1.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CAR22376.1 - 0.11 13.0 0.0 0.11 13.0 0.0 3.3 2 1 0 2 2 1 0 ABC transporter AAA_16 PF13191.6 CAR22376.1 - 0.13 12.6 0.0 0.13 12.6 0.0 3.0 2 1 0 2 2 1 0 AAA ATPase domain DivIC PF04977.15 CAR22376.1 - 0.14 11.9 33.1 0.25 11.1 4.2 5.2 3 2 1 4 4 4 0 Septum formation initiator HSF_DNA-bind PF00447.17 CAR22376.1 - 0.17 12.5 3.6 0.22 12.2 0.7 2.8 3 0 0 3 3 1 0 HSF-type DNA-binding RusA PF05866.11 CAR22376.1 - 0.25 11.9 1.8 1 9.9 1.8 2.1 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA DUF848 PF05852.11 CAR22376.1 - 1.2 9.3 32.2 0.074 13.2 11.7 3.3 2 1 1 3 3 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF948 PF06103.11 CAR22376.1 - 1.8 8.8 15.8 0.2 12.0 3.0 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) kleA_kleC PF17383.2 CAR22376.1 - 5.4 7.4 11.2 1.2 9.5 3.8 3.1 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A YabA PF06156.13 CAR22376.1 - 7.1 7.3 27.7 32 5.2 0.0 4.9 2 1 1 3 3 3 0 Initiation control protein YabA Phlebovirus_NSM PF07246.11 CAR22376.1 - 7.1 5.9 20.0 0.66 9.3 13.9 2.1 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M AAA_13 PF13166.6 CAR22377.1 - 2.2e-05 23.3 6.6 3e-05 22.9 6.6 1.1 1 0 0 1 1 1 1 AAA domain Hph PF13694.6 CAR22377.1 - 4.5e-05 23.8 15.3 0.0037 17.6 1.2 3.4 1 1 2 4 4 4 2 Sec63/Sec62 complex-interacting family DUF1664 PF07889.12 CAR22377.1 - 0.032 14.3 2.0 3.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Filament PF00038.21 CAR22377.1 - 0.033 13.8 1.4 0.055 13.1 1.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein DUF3138 PF11336.8 CAR22377.1 - 0.053 12.1 0.4 0.086 11.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FliJ PF02050.16 CAR22377.1 - 0.054 13.7 0.7 0.17 12.1 0.7 1.8 1 1 0 1 1 1 0 Flagellar FliJ protein CENP-Q PF13094.6 CAR22377.1 - 0.057 13.6 4.2 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit THOC7 PF05615.13 CAR22377.1 - 0.2 12.0 8.4 0.093 13.0 2.3 2.4 1 1 0 2 2 2 0 Tho complex subunit 7 DUF641 PF04859.12 CAR22377.1 - 0.27 11.5 3.5 0.82 10.0 0.3 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 CAR22377.1 - 0.42 11.0 5.2 0.15 12.5 2.4 1.7 2 0 0 2 2 2 0 Fez1 DivIC PF04977.15 CAR22377.1 - 0.51 10.1 3.5 5 7.0 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator MscS_porin PF12795.7 CAR22377.1 - 0.54 9.8 5.8 4.4 6.8 0.1 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF16 PF01519.16 CAR22377.1 - 2.8 8.5 5.9 7.2 7.2 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function DUF16 TMPIT PF07851.13 CAR22377.1 - 5.2 6.2 6.7 7.4 5.7 0.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein FlaC_arch PF05377.11 CAR22377.1 - 7.1 7.1 6.5 33 5.0 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 CAR22377.1 - 9.5 6.9 7.6 16 6.2 0.2 3.0 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Saw1 PF11561.8 CAR22378.1 - 5.1e-81 271.8 0.0 5.8e-81 271.6 0.0 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Aldedh PF00171.22 CAR22379.1 - 3.8e-13 48.8 0.1 2.1e-08 33.1 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family PhoLip_ATPase_C PF16212.5 CAR22380.1 - 6.1e-87 291.5 27.6 6.1e-87 291.5 27.6 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR22380.1 - 1.1e-24 85.8 5.1 4e-24 84.1 5.1 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CAR22380.1 - 2.4e-11 44.3 1.3 4.5e-06 27.1 0.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR22380.1 - 1.2e-09 38.1 0.0 4.2e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CAR22380.1 - 3.3e-06 26.7 0.1 3.3e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAR22380.1 - 0.0052 16.6 0.4 0.027 14.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ribosomal_L28e PF01778.17 CAR22381.1 - 1.2e-39 135.6 2.2 1.2e-39 135.6 2.2 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CAR22381.1 - 1.7e-29 102.4 17.0 1.7e-29 102.4 17.0 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 CAR22381.1 - 0.0062 15.9 15.9 0.0078 15.6 15.9 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 CAR22381.1 - 0.018 14.8 0.8 0.026 14.3 0.8 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain RFamide_26RFa PF11109.8 CAR22381.1 - 0.25 11.8 1.7 0.29 11.6 0.4 1.7 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 Nop14 PF04147.12 CAR22381.1 - 9.5 4.3 23.3 11 4.1 23.3 1.1 1 0 0 1 1 1 0 Nop14-like family RasGEF PF00617.19 CAR22382.1 - 1.8e-38 132.5 1.1 1.8e-38 132.5 1.1 2.8 1 1 1 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 CAR22382.1 - 1.5e-15 57.3 0.9 1.5e-15 57.3 0.9 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif Zn_clus PF00172.18 CAR22383.1 - 3.5e-11 43.0 9.7 5.9e-11 42.3 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RBDV_coat PF06593.11 CAR22383.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein PND PF17949.1 CAR22383.1 - 0.15 12.3 1.0 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 FANCM pseudonuclease domain LDB19 PF13002.7 CAR22384.1 - 6e-75 251.2 0.1 9.1e-75 250.6 0.1 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 CAR22384.1 - 0.00048 20.2 0.1 0.0011 19.0 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain AATF-Che1 PF13339.6 CAR22384.1 - 0.13 13.0 4.2 1.5 9.5 3.6 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF2756 PF10956.8 CAR22384.1 - 0.27 11.8 2.0 5 7.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) SLX9 PF15341.6 CAR22384.1 - 0.29 11.5 5.2 0.1 13.0 1.8 1.9 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 PMT PF02366.18 CAR22385.1 - 1.8e-99 332.3 18.5 1.8e-99 332.3 18.5 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR22385.1 - 1.1e-60 204.7 9.7 1.1e-60 204.7 9.7 2.9 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR22385.1 - 4.7e-23 82.0 0.0 7.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 MIR domain Nucleoside_tran PF01733.18 CAR22386.1 - 4.4e-54 184.0 32.8 6.6e-38 130.8 9.7 3.0 2 1 1 3 3 3 2 Nucleoside transporter Phage_holin_3_3 PF16083.5 CAR22386.1 - 2.9 8.1 13.5 0.51 10.5 0.5 3.7 4 0 0 4 4 4 0 LydA holin phage, holin superfamily III Exo_endo_phos PF03372.23 CAR22387.1 - 8.1e-23 81.2 0.1 3.6e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 CAR22387.1 - 8.7e-15 54.2 25.4 1.3e-07 31.3 2.7 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CAR22387.1 - 1.4e-11 44.4 9.2 1.4e-07 31.7 1.8 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAR22387.1 - 0.00082 19.6 3.6 2.1 9.2 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 CAR22387.1 - 0.12 12.5 3.0 1.4 9.2 0.3 3.1 2 0 0 2 2 2 0 Leucine Rich repeat GPCR_chapero_1 PF11904.8 CAR22387.1 - 0.14 11.6 1.0 0.25 10.7 1.0 1.4 1 0 0 1 1 1 0 GPCR-chaperone RCC1_2 PF13540.6 CAR22388.1 - 1.4e-09 37.5 21.4 0.0044 16.8 0.1 5.6 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CAR22388.1 - 6.1e-09 36.4 9.1 0.0082 16.8 0.1 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.23 CAR22389.1 - 8.7e-60 202.3 1.4 1.1e-59 201.9 0.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR22389.1 - 3.7e-21 75.5 0.1 8.3e-18 64.8 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CAR22389.1 - 9.2e-13 48.6 0.1 4.9e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR22389.1 - 0.00011 21.5 0.1 0.00033 20.0 0.1 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ribos_L4_asso_C PF14374.6 CAR22389.1 - 0.89 9.7 3.4 0.59 10.2 0.0 2.4 2 0 0 2 2 2 0 60S ribosomal protein L4 C-terminal domain Gal11_ABD1 PF18535.1 CAR22390.1 - 1.9e-40 136.9 9.6 1.9e-40 136.9 9.6 8.5 5 2 2 7 7 7 1 Gal11 activator-binding domain (ABD1) Med15_fungi PF05397.12 CAR22390.1 - 2.8e-33 114.5 6.6 2.8e-33 114.5 6.6 6.3 6 2 1 7 7 7 1 Mediator complex subunit 15 KIX_2 PF16987.5 CAR22390.1 - 3.7e-19 68.5 1.8 3.7e-19 68.5 1.8 5.0 4 1 0 4 4 4 1 KIX domain RSS_P20 PF11757.8 CAR22390.1 - 0.12 12.8 5.2 0.07 13.6 1.2 2.8 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain GSH_synth_ATP PF03917.17 CAR22391.1 - 2.4e-126 421.5 0.0 2.7e-126 421.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CAR22391.1 - 1.4e-31 109.0 0.0 2.3e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Apo-CIII PF05778.12 CAR22391.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) EI24 PF07264.11 CAR22392.1 - 9.8e-06 25.9 21.9 9.8e-06 25.9 21.9 1.9 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) EI24 PF07264.11 CAR22393.1 - 1.8e-07 31.5 7.8 2.5e-07 31.1 7.8 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Tetraspanin PF00335.20 CAR22393.1 - 1.1 8.9 5.2 0.28 10.9 0.1 2.0 1 1 1 2 2 2 0 Tetraspanin family FecCD PF01032.18 CAR22394.1 - 0.021 13.9 1.6 0.021 13.9 1.6 2.1 2 0 0 2 2 2 0 FecCD transport family DUF1772 PF08592.11 CAR22394.1 - 3.3 8.0 6.5 0.33 11.3 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 CAR22395.1 - 3.7e-62 210.1 0.0 6e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22395.1 - 9.7e-23 80.8 0.0 1.6e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22395.1 - 2.7e-07 30.2 0.0 4.6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR22395.1 - 0.0045 16.9 0.1 0.0078 16.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAR22395.1 - 0.0098 15.5 1.6 0.014 15.0 0.2 1.9 2 0 0 2 2 2 1 RIO1 family PAS_9 PF13426.7 CAR22395.1 - 0.012 15.9 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 PAS domain Seadorna_VP7 PF07387.11 CAR22395.1 - 0.015 14.3 0.1 0.036 13.1 0.1 1.6 1 0 0 1 1 1 0 Seadornavirus VP7 PAS PF00989.25 CAR22395.1 - 0.017 15.1 0.0 3.3 7.7 0.0 2.8 2 1 0 2 2 2 0 PAS fold Kdo PF06293.14 CAR22395.1 - 0.018 14.4 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CAR22395.1 - 0.026 13.3 0.0 0.051 12.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CAR22395.1 - 0.082 12.5 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 GspL_C PF12693.7 CAR22396.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 GspL periplasmic domain HEAT PF02985.22 CAR22397.1 - 2e-36 120.9 18.6 0.0094 16.1 0.0 13.0 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 CAR22397.1 - 1.7e-30 105.3 0.6 2.4e-07 31.0 0.0 7.8 4 3 3 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 CAR22397.1 - 2.7e-11 43.9 6.0 0.062 13.9 0.0 7.9 3 3 4 8 8 8 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CAR22397.1 - 1.1e-10 40.7 7.9 0.0003 19.5 1.5 4.1 1 1 2 4 4 4 3 Adaptin N terminal region HEAT_EZ PF13513.6 CAR22397.1 - 1.2e-09 38.4 5.2 19 5.9 0.1 8.2 8 0 0 8 8 8 0 HEAT-like repeat Cnd1 PF12717.7 CAR22397.1 - 1.4e-07 31.7 14.7 0.037 14.1 0.9 6.2 2 1 6 8 8 8 6 non-SMC mitotic condensation complex subunit 1 API5 PF05918.11 CAR22397.1 - 0.0095 14.8 8.4 0.12 11.1 0.1 4.8 3 2 2 5 5 5 1 Apoptosis inhibitory protein 5 (API5) M11L PF11099.8 CAR22397.1 - 0.012 15.9 4.5 0.66 10.2 0.1 3.7 3 1 1 4 4 4 0 Apoptosis regulator M11L like Arm PF00514.23 CAR22397.1 - 0.03 14.4 1.6 12 6.1 0.0 4.4 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat nsp7 PF08716.10 CAR22397.1 - 0.04 14.5 0.5 0.22 12.2 0.5 2.3 1 0 0 1 1 1 0 nsp7 replicase HhH-GPD PF00730.25 CAR22398.1 - 1.3e-18 67.4 0.0 2.5e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CAR22398.1 - 9.6e-05 22.1 0.3 0.00026 20.7 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif Exo_endo_phos PF03372.23 CAR22399.1 - 3.6e-14 52.9 0.0 5.7e-14 52.2 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Phenyl_P_gamma PF09662.10 CAR22399.1 - 0.086 13.0 0.0 0.68 10.1 0.0 2.3 1 1 1 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) Paf1 PF03985.13 CAR22400.1 - 0.064 12.3 17.8 0.83 8.6 0.4 2.0 2 0 0 2 2 2 0 Paf1 Activator_LAG-3 PF11498.8 CAR22400.1 - 0.1 11.5 41.3 0.012 14.6 34.1 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 LMBR1 PF04791.16 CAR22400.1 - 0.23 10.3 6.4 0.25 10.2 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM60A PF15396.6 CAR22400.1 - 0.37 10.8 10.6 0.31 11.0 7.1 2.0 2 0 0 2 2 2 0 Protein Family FAM60A SurA_N_2 PF13623.6 CAR22400.1 - 3.8 7.4 21.6 7.7 6.4 21.6 1.4 1 0 0 1 1 1 0 SurA N-terminal domain DUF4446 PF14584.6 CAR22400.1 - 4.2 7.4 6.5 7.8 6.5 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Presenilin PF01080.17 CAR22400.1 - 4.8 5.9 13.3 7.3 5.2 13.3 1.2 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.16 CAR22400.1 - 5.3 5.8 23.2 8.5 5.1 23.2 1.4 1 0 0 1 1 1 0 Androgen receptor SET PF00856.28 CAR22400.1 - 7.7 6.9 7.7 11 6.3 7.6 1.3 1 1 0 1 1 1 0 SET domain SNARE PF05739.19 CAR22401.1 - 4.3e-08 33.0 0.4 9.4e-08 31.9 0.4 1.5 1 0 0 1 1 1 1 SNARE domain YkyA PF10368.9 CAR22401.1 - 0.13 11.9 1.7 3 7.5 0.1 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein RRM_1 PF00076.22 CAR22402.1 - 2.9e-19 68.6 3.3 8e-15 54.4 0.3 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR22402.1 - 0.00027 21.0 2.2 1.1 9.4 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CAR22402.1 - 0.043 13.4 0.7 8.9 5.9 0.1 2.5 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 CAR22403.1 - 5.4e-50 170.4 0.1 1.4e-49 169.1 0.1 1.7 1 0 0 1 1 1 1 Sds3-like Ribosomal_S19 PF00203.21 CAR22404.1 - 6.9e-34 115.6 0.1 9.7e-34 115.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 CAR22405.1 - 2.4e-25 89.0 12.9 2.9e-25 88.7 12.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cys_Met_Meta_PP PF01053.20 CAR22406.1 - 1.3e-142 474.9 0.0 1.4e-142 474.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CAR22406.1 - 0.0035 15.9 0.0 0.0054 15.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_5 PF00266.19 CAR22406.1 - 0.039 12.9 0.1 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V SIL1 PF16782.5 CAR22407.1 - 2.1e-97 325.8 0.0 2.5e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Peptidase_M15_3 PF08291.11 CAR22407.1 - 0.13 12.3 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase M15 DUF775 PF05603.12 CAR22408.1 - 4.6e-61 205.8 0.0 5.3e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) TFIID_30kDa PF03540.13 CAR22408.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit tRNA-synt_1c PF00749.21 CAR22409.1 - 2.6e-106 355.1 0.0 3.8e-106 354.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SMC_N PF02463.19 CAR22410.1 - 1e-23 84.0 16.7 6.3e-23 81.4 16.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR22410.1 - 6.2e-22 79.1 3.9 6.2e-22 79.1 3.9 4.9 2 2 2 4 4 2 1 AAA domain AAA_15 PF13175.6 CAR22410.1 - 8.7e-06 25.7 8.9 8.7e-06 25.7 8.9 3.6 2 2 1 3 3 2 1 AAA ATPase domain AAA_21 PF13304.6 CAR22410.1 - 2.2e-05 24.4 0.3 0.012 15.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR22410.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CAR22410.1 - 0.021 15.3 17.5 0.1 13.1 0.0 4.9 3 2 0 4 4 4 0 ABC transporter AAA_25 PF13481.6 CAR22410.1 - 0.033 13.7 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR22410.1 - 0.061 13.2 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 NACHT domain NTS_2 PF15448.6 CAR22410.1 - 0.09 13.2 0.1 0.31 11.4 0.1 1.9 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein DUF3618 PF12277.8 CAR22410.1 - 0.37 11.1 2.5 2.3 8.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) LPP PF04728.13 CAR22410.1 - 1.9 8.9 7.6 30 5.1 1.9 4.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper PE_PPE_C PF12484.8 CAR22411.1 - 0.16 12.9 4.1 0.42 11.6 4.1 1.7 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal MDM10 PF12519.8 CAR22412.1 - 5.3e-151 503.6 14.5 6e-151 503.5 14.5 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 IGPD PF00475.18 CAR22412.1 - 0.046 14.0 0.0 7.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase RuvC_1 PF18516.1 CAR22412.1 - 0.091 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 RuvC nuclease domain C2-set_2 PF08205.12 CAR22412.1 - 0.1 12.7 1.7 6.1 7.0 0.4 2.6 2 0 0 2 2 2 0 CD80-like C2-set immunoglobulin domain Spo7 PF03907.13 CAR22413.1 - 8.4e-71 238.0 4.2 1.2e-70 237.5 4.2 1.2 1 0 0 1 1 1 1 Spo7-like protein DUF2208 PF09973.9 CAR22413.1 - 0.0011 18.6 0.8 0.0015 18.2 0.8 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) OPT PF03169.15 CAR22413.1 - 0.07 11.7 0.1 0.092 11.4 0.1 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF4538 PF15061.6 CAR22413.1 - 0.073 12.8 0.3 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) B56 PF01603.20 CAR22414.1 - 1.1e-171 571.4 7.7 1.7e-171 570.8 7.7 1.2 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Zip PF02535.22 CAR22414.1 - 7 5.8 5.2 9.5 5.3 5.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 CAR22414.1 - 9.2 4.8 10.2 13 4.3 10.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FUN14 PF04930.15 CAR22415.1 - 5.1e-08 33.2 1.2 2.7e-07 30.9 0.4 2.2 2 0 0 2 2 2 1 FUN14 family MtrF PF09472.10 CAR22415.1 - 0.096 12.1 0.4 0.096 12.1 0.4 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) zf_CCCH_4 PF18345.1 CAR22416.1 - 8e-13 48.0 32.2 6.6e-06 26.0 2.5 5.3 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH PF00642.24 CAR22416.1 - 4.2e-12 45.6 29.4 0.00051 19.9 0.6 5.5 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAR22416.1 - 5.7e-09 36.7 22.6 0.0025 18.5 0.4 5.2 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 CAR22416.1 - 6.3e-07 29.6 14.1 1.3e-06 28.6 7.0 2.2 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CAR22416.1 - 0.029 14.2 1.3 0.029 14.2 1.3 4.7 5 1 0 5 5 5 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CAR22416.1 - 1.1 9.9 22.7 0.61 10.6 1.1 4.8 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 CAR22417.1 - 2.1e-27 96.1 0.0 3.4e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22417.1 - 2.2e-10 40.3 0.0 3.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR22417.1 - 0.0042 17.0 0.0 0.066 13.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pil1 PF13805.6 CAR22418.1 - 3.4e-122 407.0 0.1 4.7e-122 406.6 0.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 COG4 PF08318.12 CAR22419.1 - 1.7e-84 283.8 2.9 2.9e-84 283.0 2.9 1.4 1 0 0 1 1 1 1 COG4 transport protein Vps54_N PF10475.9 CAR22419.1 - 0.00012 21.5 5.4 0.00026 20.4 5.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Peptidase_S41_N PF11918.8 CAR22419.1 - 0.18 12.0 7.0 9.7 6.4 0.2 4.1 3 1 1 4 4 4 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Cnl2_NKP2 PF09447.10 CAR22419.1 - 0.38 10.9 2.8 0.6 10.3 0.0 2.8 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Forkhead PF00250.18 CAR22420.1 - 1.9e-24 85.8 0.0 3.9e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CAR22420.1 - 5.9e-12 45.8 0.2 1.1e-11 44.9 0.2 1.5 1 0 0 1 1 1 1 FHA domain GIDA_assoc PF13932.6 CAR22420.1 - 0.21 11.8 4.4 0.52 10.5 4.4 1.7 1 0 0 1 1 1 0 GidA associated domain Peptidase_S46 PF10459.9 CAR22420.1 - 0.43 9.2 10.8 0.66 8.5 10.8 1.2 1 0 0 1 1 1 0 Peptidase S46 Proteasome PF00227.26 CAR22421.1 - 3e-47 160.6 0.1 3.7e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.25 CAR22422.1 - 4.7e-53 180.2 0.0 7.4e-51 173.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22422.1 - 3.9e-28 98.4 0.4 5.1e-25 88.2 0.0 2.8 2 1 1 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CAR22422.1 - 0.00035 19.7 0.4 0.0051 15.8 0.0 2.0 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CAR22422.1 - 0.0086 15.4 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PHD PF00628.29 CAR22423.1 - 3.4e-09 36.4 9.4 3.4e-09 36.4 9.4 2.4 2 0 0 2 2 2 1 PHD-finger SET PF00856.28 CAR22423.1 - 7.1e-05 23.3 0.0 0.00054 20.4 0.0 2.3 1 1 0 1 1 1 1 SET domain PHD_2 PF13831.6 CAR22423.1 - 0.0094 15.5 4.2 0.0094 15.5 4.2 2.4 2 0 0 2 2 2 2 PHD-finger zf-CW PF07496.15 CAR22423.1 - 0.015 15.3 3.1 0.036 14.1 3.1 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger UPF0561 PF10573.9 CAR22423.1 - 0.082 13.0 2.2 0.26 11.4 2.2 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Pam16 PF03656.13 CAR22424.1 - 7.1e-45 152.1 2.4 8.5e-45 151.9 2.4 1.0 1 0 0 1 1 1 1 Pam16 DUF1586 PF07625.11 CAR22424.1 - 1.9 8.6 7.0 1.7 8.7 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) zf-CCCH PF00642.24 CAR22425.1 - 1.6e-07 31.1 34.8 0.0014 18.5 0.9 5.5 6 0 0 6 6 6 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAR22425.1 - 0.00034 20.3 0.5 0.00034 20.3 0.5 5.9 6 0 0 6 6 6 4 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAR22425.1 - 0.0026 17.8 1.3 0.0026 17.8 1.3 6.4 6 1 0 6 6 6 2 Zinc finger domain zf-CCCH_2 PF14608.6 CAR22425.1 - 0.02 15.3 3.7 0.02 15.3 3.7 5.2 6 0 0 6 6 6 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CAR22425.1 - 1.3 9.8 23.6 15 6.4 0.8 3.8 1 1 2 3 3 3 0 Torus domain zf-C2HC5 PF06221.13 CAR22426.1 - 3.9e-22 78.0 7.4 6.6e-22 77.3 7.4 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF2024 PF09630.10 CAR22426.1 - 0.24 11.3 0.6 0.69 9.8 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) DEAD PF00270.29 CAR22427.1 - 5.3e-39 133.8 0.0 9.4e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR22427.1 - 6.7e-19 68.3 0.0 2.1e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR22427.1 - 9.2e-18 64.2 0.1 2.1e-17 63.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAR22427.1 - 0.0069 16.4 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sin_N PF04801.13 CAR22428.1 - 7.3e-21 74.9 0.0 1.1e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region IF-2B PF01008.17 CAR22429.1 - 3.5e-76 256.1 0.0 3.9e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.27 CAR22430.1 - 1.3e-58 197.8 0.0 2e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CAR22430.1 - 1e-27 96.0 0.0 3.5e-27 94.3 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CAR22430.1 - 9.3e-18 64.0 0.2 1.7e-10 40.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR22430.1 - 2e-07 31.3 1.2 2e-07 31.3 1.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CAR22430.1 - 0.00015 21.6 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GCS PF03074.16 CAR22431.1 - 1.5e-148 495.1 0.0 2.1e-148 494.6 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase PI3_PI4_kinase PF00454.27 CAR22432.1 - 1.3e-53 182.4 0.0 2.5e-53 181.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.10 CAR22433.1 - 1.2e-51 176.0 0.1 5.1e-40 137.7 0.0 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 CAR22433.1 - 1.3e-05 25.6 0.0 2.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR22433.1 - 0.00016 21.5 0.0 0.036 14.2 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR22433.1 - 0.0024 17.9 0.3 0.034 14.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR22433.1 - 0.0033 17.2 0.3 0.029 14.2 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR22433.1 - 0.0083 16.8 0.0 0.025 15.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAR22433.1 - 0.016 15.5 0.0 0.049 14.0 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAR22433.1 - 0.032 14.5 0.0 0.11 12.8 0.0 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR22433.1 - 0.12 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAR22433.1 - 0.13 12.3 0.2 1.2 9.4 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SAPS PF04499.15 CAR22434.1 - 9.9e-181 601.8 0.1 9.9e-181 601.8 0.1 3.1 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein PTPLA PF04387.14 CAR22435.1 - 1.8e-50 170.9 7.1 3e-50 170.2 7.1 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_L21p PF00829.21 CAR22436.1 - 2.3e-14 53.5 0.1 2.8e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 CAR22437.1 - 3.4e-67 226.6 0.0 7.2e-67 225.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22437.1 - 1e-43 149.5 0.0 1.8e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22437.1 - 1.5e-11 44.2 0.0 1.5e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CAR22437.1 - 0.019 13.8 0.0 0.019 13.8 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CAR22437.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ion_trans_2 PF07885.16 CAR22438.1 - 3.4e-28 97.4 32.1 8.7e-18 64.1 7.6 3.5 4 0 0 4 4 4 2 Ion channel Phasin PF05597.11 CAR22438.1 - 0.076 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Lig_chan PF00060.26 CAR22438.1 - 0.65 9.8 15.1 0.84 9.5 0.3 3.7 3 1 0 3 3 3 0 Ligand-gated ion channel UvrD-helicase PF00580.21 CAR22439.1 - 1.5e-60 205.4 0.0 3.4e-60 204.2 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CAR22439.1 - 5.9e-47 160.7 0.0 1.1e-46 159.8 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CAR22439.1 - 6.7e-28 97.9 0.0 1.6e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CAR22439.1 - 2.9e-07 30.2 0.3 0.0014 18.4 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 CAR22439.1 - 0.0015 18.2 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR22439.1 - 0.0042 16.8 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CAR22439.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain GWT1 PF06423.12 CAR22440.1 - 3e-38 131.3 4.9 3e-38 131.3 4.9 2.3 3 1 0 3 3 3 1 GWT1 DUF4818 PF16089.5 CAR22440.1 - 0.0025 18.3 0.1 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) BatA PF07584.11 CAR22440.1 - 0.0076 16.6 2.2 0.037 14.4 1.9 2.4 1 1 0 1 1 1 1 Aerotolerance regulator N-terminal PTCB-BRCT PF12738.7 CAR22441.1 - 1.2e-12 47.6 0.1 4.8e-06 26.4 0.0 3.9 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 CAR22441.1 - 1.1e-11 44.9 0.1 0.00018 21.8 0.0 4.7 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CAR22441.1 - 1.6e-07 31.6 0.0 0.0039 17.6 0.0 3.5 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CAR22441.1 - 0.014 15.5 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Zn_clus PF00172.18 CAR22442.1 - 4.2e-10 39.6 9.7 9.1e-10 38.5 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTR2 PF15458.6 CAR22443.1 - 1e-17 64.7 17.0 1.3e-17 64.4 17.0 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DIPSY PF11763.8 CAR22443.1 - 0.058 13.6 0.9 0.13 12.4 0.1 1.9 3 0 0 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal PI3_PI4_kinase PF00454.27 CAR22444.1 - 4.9e-42 144.5 0.0 1.2e-39 136.6 0.0 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CAR22444.1 - 2.7e-26 92.1 0.1 2.7e-26 92.1 0.1 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) FlaF PF07309.11 CAR22444.1 - 0.22 11.5 1.2 6.5 6.8 0.0 3.7 4 1 0 4 4 4 0 Flagellar protein FlaF Aconitase PF00330.20 CAR22445.1 - 3.7e-148 494.3 0.0 4.6e-148 494.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR22445.1 - 1.1e-45 155.1 0.0 2.1e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Cys_Met_Meta_PP PF01053.20 CAR22446.1 - 1e-146 488.4 0.0 1.1e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CAR22446.1 - 4.7e-10 39.2 0.0 7.1e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CAR22446.1 - 1.6e-09 37.5 0.1 2.8e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CAR22446.1 - 6.9e-09 35.1 0.2 1.2e-08 34.4 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAR22446.1 - 2.9e-06 26.8 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CAR22446.1 - 0.00014 20.5 0.8 0.00043 18.9 0.8 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 CAR22446.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain GDC-P PF02347.16 CAR22446.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein CPSase_L_D2 PF02786.17 CAR22446.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Zn_clus PF00172.18 CAR22447.1 - 3.8e-06 26.9 11.2 7.2e-06 26.0 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gtr1_RagA PF04670.12 CAR22448.1 - 2e-67 226.9 0.3 2.5e-67 226.6 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CAR22448.1 - 0.011 15.2 0.0 0.022 14.2 0.0 1.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.6 CAR22448.1 - 0.035 14.1 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TYW3 PF02676.14 CAR22449.1 - 1.9e-65 220.2 0.0 2.4e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 MIF4G PF02854.19 CAR22450.1 - 1.2e-44 152.5 0.2 1.6e-44 152.1 0.2 1.2 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CAR22450.1 - 7.5e-26 90.1 0.1 2.7e-25 88.3 0.1 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Fucose_iso_N2 PF07882.12 CAR22450.1 - 0.039 13.5 0.2 0.091 12.3 0.2 1.5 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain AAA PF00004.29 CAR22451.1 - 7.6e-43 146.1 0.0 1.4e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR22451.1 - 1.4e-14 53.6 0.5 3.9e-14 52.2 0.1 2.1 3 0 0 3 3 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CAR22451.1 - 5.9e-07 29.3 0.7 1.4e-06 28.2 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CAR22451.1 - 2.8e-06 27.6 0.0 5.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAR22451.1 - 4.1e-06 26.8 0.0 2.5e-05 24.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR22451.1 - 3.4e-05 24.3 0.0 0.0003 21.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAR22451.1 - 5.2e-05 23.5 0.2 0.0064 16.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAR22451.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CAR22451.1 - 0.0015 18.3 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CAR22451.1 - 0.002 18.7 0.2 0.023 15.3 0.0 2.6 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CAR22451.1 - 0.0025 18.0 0.0 0.0053 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAR22451.1 - 0.0045 17.2 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CAR22451.1 - 0.0072 16.2 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.9 CAR22451.1 - 0.0087 16.3 0.2 0.017 15.4 0.2 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein TIP49 PF06068.13 CAR22451.1 - 0.011 15.0 0.0 0.028 13.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR22451.1 - 0.012 15.1 0.2 0.028 13.8 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 CAR22451.1 - 0.019 14.4 0.0 0.077 12.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 CAR22451.1 - 0.02 14.9 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CAR22451.1 - 0.022 14.8 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CAR22451.1 - 0.031 14.0 0.0 0.18 11.5 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 CAR22451.1 - 0.048 14.0 0.1 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAR22451.1 - 0.049 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAR22451.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CAR22451.1 - 0.054 13.2 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3372 PF11852.8 CAR22451.1 - 0.057 12.9 0.2 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) AAA_7 PF12775.7 CAR22451.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 CAR22451.1 - 0.096 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CAR22451.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CAR22451.1 - 0.11 12.2 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAR22451.1 - 0.11 11.7 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Glyco_tran_28_C PF04101.16 CAR22452.1 - 1.8e-20 73.6 0.0 7.2e-20 71.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2046 PF09755.9 CAR22453.1 - 0.005 16.1 0.1 0.0088 15.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) PRKG1_interact PF15898.5 CAR22453.1 - 0.0057 17.5 0.5 0.011 16.6 0.5 1.4 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain MerR_2 PF13591.6 CAR22453.1 - 0.051 13.4 0.6 0.089 12.7 0.6 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein MCM3AP_GANP PF16769.5 CAR22453.1 - 0.1 10.8 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF3678 PF12435.8 CAR22453.1 - 6.5 6.2 13.1 1.3 8.5 3.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) RRM_1 PF00076.22 CAR22455.1 - 2.9e-40 135.9 0.0 5.6e-19 67.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR22455.1 - 0.0085 16.2 0.0 2.4 8.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CAR22455.1 - 0.081 12.9 0.1 5.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arrestin_N PF00339.29 CAR22456.1 - 1.6e-20 73.6 0.0 3.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CAR22456.1 - 3.5e-07 30.7 0.4 2.6e-06 27.9 0.1 2.5 2 1 1 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Vps26 PF03643.15 CAR22456.1 - 0.0025 16.8 0.2 0.064 12.3 0.0 2.5 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 26 RNase_PH PF01138.21 CAR22457.1 - 4.7e-22 78.9 0.1 6.5e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.13 CAR22458.1 - 4.8e-56 187.7 9.9 6.3e-31 106.9 0.3 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 CAR22458.1 - 0.0056 17.2 0.5 0.25 11.9 0.5 2.7 1 1 0 1 1 1 1 SKICH domain PITH PF06201.13 CAR22459.1 - 1.6e-37 129.0 0.1 2.1e-37 128.7 0.1 1.1 1 0 0 1 1 1 1 PITH domain ALAD PF00490.21 CAR22460.1 - 6.2e-116 387.0 0.0 7.6e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Snf7 PF03357.21 CAR22461.1 - 1.2e-29 103.1 3.7 1.4e-29 102.9 3.7 1.1 1 0 0 1 1 1 1 Snf7 DUF1989 PF09347.10 CAR22462.1 - 9.2e-55 184.8 0.0 1.1e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) PALP PF00291.25 CAR22463.1 - 1.2e-60 205.4 0.0 1.7e-60 205.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CAR22463.1 - 7.6e-19 67.9 0.0 2.3e-11 43.9 0.0 2.6 2 0 0 2 2 2 2 CBS domain ComZ PF10815.8 CAR22464.1 - 0.00012 22.0 0.1 0.0002 21.3 0.1 1.3 1 0 0 1 1 1 1 ComZ DUF1641 PF07849.11 CAR22464.1 - 0.0016 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1641) TFIIS_M PF07500.14 CAR22465.1 - 3.4e-24 85.5 0.4 3.4e-24 85.5 0.4 2.2 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CAR22465.1 - 3.8e-17 61.9 6.1 6.2e-17 61.2 6.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CAR22465.1 - 1.4e-09 37.8 0.7 1.4e-09 37.8 0.7 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain IML1 PF12257.8 CAR22465.1 - 0.26 10.4 1.3 3.8 6.6 0.1 2.1 2 0 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 RRM_1 PF00076.22 CAR22466.1 - 3.4e-20 71.6 0.0 6e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CAR22466.1 - 2.4e-10 40.7 1.7 2.4e-10 40.7 1.7 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CAR22466.1 - 3.8e-10 39.2 2.8 3.8e-10 39.2 2.8 2.2 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 CAR22466.1 - 0.0055 16.5 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif LIDHydrolase PF10230.9 CAR22466.1 - 0.048 13.2 0.1 0.064 12.8 0.1 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase CSTF2_hinge PF14327.6 CAR22467.1 - 3.4e-24 85.1 1.2 3.4e-24 85.1 1.2 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CAR22467.1 - 3e-06 26.7 5.4 6.2e-06 25.7 5.4 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_1 PF00076.22 CAR22467.1 - 0.00013 21.7 0.0 0.00077 19.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_1_2 PF00155.21 CAR22468.1 - 1.1e-79 268.3 0.0 1.2e-79 268.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II TrmO_C PF18389.1 CAR22468.1 - 0.12 12.5 0.1 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 TrmO C-terminal domain SNARE PF05739.19 CAR22469.1 - 2.2e-15 56.4 0.7 2.2e-15 56.4 0.7 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CAR22469.1 - 4e-05 23.4 8.0 0.0003 20.5 0.7 2.6 2 1 0 2 2 2 2 Syntaxin DUF16 PF01519.16 CAR22469.1 - 0.034 14.6 0.5 0.034 14.6 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Syntaxin-5_N PF11416.8 CAR22469.1 - 0.051 12.8 0.9 0.051 12.8 0.9 2.8 3 0 0 3 3 3 0 Syntaxin-5 N-terminal, Sly1p-binding domain Serine_rich PF08824.10 CAR22469.1 - 0.063 13.3 1.9 5.3 7.0 0.2 2.4 2 1 0 2 2 2 0 Serine rich protein interaction domain Syntaxin-18_N PF10496.9 CAR22469.1 - 0.11 12.8 1.2 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus FlaC_arch PF05377.11 CAR22469.1 - 0.28 11.6 3.8 5.4 7.5 0.6 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MCPsignal PF00015.21 CAR22469.1 - 0.29 10.9 6.6 0.068 13.0 0.9 2.4 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.12 CAR22469.1 - 0.53 10.3 7.3 0.68 10.0 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) V-SNARE PF05008.15 CAR22469.1 - 1.8 9.0 6.1 0.35 11.3 0.3 2.7 3 2 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus MutS_III PF05192.18 CAR22469.1 - 2.4 8.3 5.4 4.6 7.4 5.4 1.5 1 1 0 1 1 1 0 MutS domain III YabA PF06156.13 CAR22469.1 - 2.5 8.8 8.1 1.2 9.8 1.0 2.8 3 0 0 3 3 3 0 Initiation control protein YabA HrpB7 PF09486.10 CAR22469.1 - 6.5 7.1 13.5 3.9 7.8 6.5 2.9 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.9 CAR22469.1 - 8.1 6.8 9.8 2.8 8.3 0.7 3.2 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snf7 PF03357.21 CAR22470.1 - 1.2e-50 171.4 13.4 1.2e-50 171.4 13.4 1.9 2 0 0 2 2 2 1 Snf7 Ribosomal_60s PF00428.19 CAR22470.1 - 0.01 16.4 9.6 0.01 16.4 9.6 2.0 1 1 1 2 2 2 0 60s Acidic ribosomal protein Cupin_8 PF13621.6 CAR22470.1 - 0.28 10.8 2.6 0.41 10.3 2.4 1.3 1 1 0 1 1 1 0 Cupin-like domain PIN_8 PF18476.1 CAR22470.1 - 0.81 9.5 7.5 0.52 10.1 5.3 1.7 1 1 1 2 2 2 0 PIN like domain NRBF2 PF08961.10 CAR22471.1 - 0.0024 17.5 1.7 0.0037 16.9 1.7 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator Cnn_1N PF07989.11 CAR22471.1 - 0.039 14.1 3.7 0.11 12.6 3.8 1.8 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 CAR22471.1 - 0.045 14.2 6.2 0.24 11.9 5.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CAR22471.1 - 0.074 12.8 7.0 0.16 11.8 7.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Nnf1 PF03980.14 CAR22471.1 - 1 9.7 10.7 0.16 12.4 3.8 2.4 2 1 1 3 3 3 0 Nnf1 DUF4407 PF14362.6 CAR22471.1 - 5.6 6.2 9.5 6.8 5.9 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_60s PF00428.19 CAR22471.1 - 6.5 7.4 8.4 2.8 8.6 2.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sdh_cyt PF01127.22 CAR22472.1 - 4.9e-28 97.6 4.1 6.1e-28 97.3 4.1 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abhydrolase_1 PF00561.20 CAR22473.1 - 1.6e-30 106.6 0.2 2.1e-30 106.3 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CAR22473.1 - 1.6e-19 69.3 0.2 2.7e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CAR22473.1 - 8.1e-05 22.0 0.0 0.0058 15.9 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 CAR22473.1 - 0.017 14.8 0.0 4.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pkinase PF00069.25 CAR22474.1 - 1.5e-75 253.9 0.0 1.9e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22474.1 - 1.5e-32 112.9 0.0 2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22474.1 - 8.3e-06 25.3 0.0 2.2e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CAR22474.1 - 2.3e-05 23.5 0.3 4.9e-05 22.4 0.3 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CAR22474.1 - 0.0037 16.1 0.1 0.0062 15.4 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR22474.1 - 0.0051 16.2 0.1 0.015 14.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR22474.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAR22474.1 - 0.12 11.4 0.1 0.17 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Spc24 PF08286.11 CAR22475.1 - 3.1e-19 69.2 6.0 4e-18 65.6 0.1 2.5 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 ING PF12998.7 CAR22475.1 - 0.018 15.7 4.0 1.9 9.1 0.3 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Exonuc_VII_L PF02601.15 CAR22475.1 - 0.024 14.2 6.0 0.028 14.0 6.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Bul1_C PF04426.12 CAR22475.1 - 0.094 12.1 2.5 0.11 11.9 2.0 1.3 1 1 0 1 1 1 0 Bul1 C terminus OmpH PF03938.14 CAR22475.1 - 0.27 11.6 9.7 0.81 10.0 9.7 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MSA_2 PF00985.17 CAR22475.1 - 0.29 11.5 1.8 0.34 11.2 0.3 1.8 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family Syntaxin-6_N PF09177.11 CAR22475.1 - 0.29 11.7 5.9 0.88 10.2 1.4 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FapA PF03961.13 CAR22475.1 - 0.42 9.2 7.0 0.54 8.8 7.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliJ PF02050.16 CAR22475.1 - 0.43 10.8 9.7 1.4 9.1 8.1 2.2 1 1 0 1 1 1 0 Flagellar FliJ protein Baculo_PEP_C PF04513.12 CAR22475.1 - 0.77 9.8 6.4 5 7.2 2.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF919 PF06034.11 CAR22475.1 - 1.5 8.7 6.9 9.9 6.1 0.8 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Hemagglutinin PF00509.18 CAR22475.1 - 1.8 6.9 4.3 9.3 4.5 0.6 2.0 2 0 0 2 2 2 0 Haemagglutinin TMPIT PF07851.13 CAR22475.1 - 2 7.6 4.5 1.8 7.7 3.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein ABC_tran_CTD PF16326.5 CAR22475.1 - 4.8 7.5 14.2 17 5.7 5.3 3.0 2 1 1 3 3 3 0 ABC transporter C-terminal domain DUF3552 PF12072.8 CAR22475.1 - 5.7 6.3 18.7 0.72 9.2 4.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) HAUS6_N PF14661.6 CAR22475.1 - 8.4 5.9 9.3 53 3.3 9.3 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RP-C_C PF11800.8 CAR22475.1 - 9.4 6.3 10.6 2.9 7.9 0.9 2.1 1 1 1 2 2 2 0 Replication protein C C-terminal region L31 PF09784.9 CAR22476.1 - 3.9e-41 139.6 2.4 7e-41 138.8 2.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.10 CAR22477.1 - 4.4e-19 68.3 2.2 7.2e-19 67.6 2.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CAR22477.1 - 0.043 13.9 0.5 0.16 12.2 0.5 2.0 1 1 1 2 2 2 0 CHCH domain COX17 PF05051.13 CAR22477.1 - 0.61 10.5 4.6 5.6 7.4 0.8 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Adaptin_N PF01602.20 CAR22478.1 - 7.9e-125 417.4 16.6 9.7e-125 417.1 16.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR22478.1 - 1.6e-55 187.6 13.4 1.2e-54 184.7 4.0 3.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR22478.1 - 6.8e-13 48.8 0.5 2e-07 31.3 0.1 5.2 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 CAR22478.1 - 4.2e-09 35.9 2.4 0.045 14.0 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 CAR22478.1 - 0.00056 20.4 3.4 1.3 9.6 0.0 4.7 6 0 0 6 6 5 2 HEAT-like repeat RTP1_C1 PF10363.9 CAR22478.1 - 0.0013 18.9 8.0 0.011 15.9 0.1 5.0 3 1 3 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm_2 PF04826.13 CAR22478.1 - 0.0045 16.5 0.9 0.0045 16.5 0.9 2.5 2 1 1 3 3 3 1 Armadillo-like Cnd3 PF12719.7 CAR22478.1 - 0.0069 15.6 1.8 0.11 11.7 0.1 3.0 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Atx10homo_assoc PF09759.9 CAR22478.1 - 0.039 14.0 0.5 0.52 10.4 0.1 3.1 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 CAR22478.1 - 0.11 12.6 2.4 1.2 9.3 0.3 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CAR22478.1 - 0.12 12.5 0.5 7.4 6.7 0.1 3.4 2 2 0 2 2 2 0 V-ATPase subunit H Gene66 PF02053.15 CAR22478.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Gene 66 (IR5) protein WD40 PF00400.32 CAR22479.1 - 3.8e-47 157.3 8.3 4.7e-08 33.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22479.1 - 1.3e-10 41.4 1.1 0.04 14.2 0.0 4.8 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR22479.1 - 4e-07 29.1 5.8 0.065 11.9 0.0 4.9 2 1 3 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CAR22479.1 - 8.4e-07 29.1 1.2 9.3e-06 25.6 0.1 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR22479.1 - 3.4e-06 26.2 1.1 0.064 12.2 0.0 3.7 1 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein nos_propeller PF18764.1 CAR22479.1 - 0.016 15.1 0.1 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat DUF1513 PF07433.11 CAR22479.1 - 0.043 12.9 0.2 0.34 10.0 0.0 2.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1513) PD40 PF07676.12 CAR22479.1 - 0.12 12.3 0.0 11 6.1 0.0 3.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat SPG4 PF17325.2 CAR22480.1 - 6.1e-42 143.1 1.0 6.8e-42 143.0 1.0 1.0 1 0 0 1 1 1 1 Stationary phase protein 4 Hydant_A_N PF05378.13 CAR22480.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region TPP_enzyme_N PF02776.18 CAR22481.1 - 3.7e-54 182.9 0.2 1e-53 181.4 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CAR22481.1 - 6.2e-52 175.5 0.1 2.7e-50 170.1 0.1 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR22481.1 - 5e-40 136.4 0.3 1.2e-39 135.2 0.1 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 CAR22481.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Myosin_head PF00063.21 CAR22482.1 - 1e-233 777.5 7.8 1.3e-233 777.1 7.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CAR22482.1 - 2.1e-48 164.5 0.1 3.6e-48 163.7 0.1 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CAR22482.1 - 2.5e-11 43.0 0.0 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR22482.1 - 8.3e-08 32.0 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR22482.1 - 1.9e-05 24.3 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 CAR22482.1 - 0.02 15.3 0.0 0.068 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CAR22482.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 CAR22482.1 - 0.054 13.0 0.1 8.9 5.8 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 CAR22482.1 - 0.058 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CAR22482.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Aldedh PF00171.22 CAR22483.1 - 7.4e-70 235.7 0.0 8.9e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4092 PF13322.6 CAR22483.1 - 0.0071 16.2 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4092) She2p PF11435.8 CAR22484.1 - 4.6e-88 294.2 8.0 5.8e-88 293.8 8.0 1.1 1 0 0 1 1 1 1 RNA binding protein She2p RasGAP_C PF03836.15 CAR22484.1 - 0.066 13.4 1.0 7.9 6.6 0.3 2.6 2 0 0 2 2 2 0 RasGAP C-terminus SFTA2 PF15210.6 CAR22484.1 - 0.29 11.1 1.3 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Surfactant-associated protein 2 GCR1_C PF12550.8 CAR22485.1 - 5.4e-22 77.9 0.1 1.1e-21 77.0 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes PAS PF00989.25 CAR22485.1 - 0.0019 18.2 0.4 0.013 15.4 0.1 2.5 3 0 0 3 3 3 1 PAS fold Pex19 PF04614.12 CAR22485.1 - 0.015 15.1 0.3 0.034 13.9 0.3 1.5 1 0 0 1 1 1 0 Pex19 protein family Leu_zip PF15294.6 CAR22485.1 - 0.045 13.3 3.9 0.066 12.7 3.9 1.2 1 0 0 1 1 1 0 Leucine zipper DUF977 PF06163.11 CAR22485.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Popeye PF04831.13 CAR22485.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Popeye protein conserved region STAT_alpha PF01017.20 CAR22485.1 - 0.22 11.4 3.1 0.38 10.6 3.1 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain Med11 PF10280.9 CAR22486.1 - 2.5e-13 50.6 1.4 5.7e-13 49.5 1.4 1.6 1 1 0 1 1 1 1 Mediator complex protein NEMO PF11577.8 CAR22486.1 - 0.014 15.4 5.5 0.46 10.5 0.2 3.1 2 1 0 3 3 3 0 NF-kappa-B essential modulator NEMO Mur_ligase_M PF08245.12 CAR22487.1 - 9.6e-09 35.5 0.3 2.5e-08 34.1 0.3 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CAR22487.1 - 0.077 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain SRAP PF02586.14 CAR22488.1 - 2.6e-67 226.6 1.1 4e-67 226.0 1.1 1.3 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) SNAP PF14938.6 CAR22489.1 - 0.00088 18.8 2.0 0.16 11.4 0.1 2.5 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP Pex14_N PF04695.13 CAR22489.1 - 0.044 14.4 0.1 0.12 13.1 0.1 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_12 PF13424.6 CAR22489.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR22489.1 - 0.23 11.7 5.5 12 6.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Swi5 PF07061.11 CAR22489.1 - 1.2 9.3 4.9 0.46 10.6 0.5 2.4 3 0 0 3 3 3 0 Swi5 Peptidase_M3 PF01432.20 CAR22490.1 - 8.2e-129 430.8 0.0 1.1e-128 430.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.6 CAR22490.1 - 0.043 14.1 0.2 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 Effector protein Peptidase_M50B PF13398.6 CAR22490.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Ku PF02735.16 CAR22491.1 - 3.4e-35 121.6 0.0 5.1e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CAR22491.1 - 2e-14 53.9 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 CAR22491.1 - 0.0019 18.5 0.0 0.0052 17.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain PGM_PMM_I PF02878.16 CAR22492.1 - 2.7e-34 117.8 0.1 4.6e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CAR22492.1 - 3e-26 91.9 0.0 5.8e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CAR22492.1 - 4.7e-14 52.9 0.0 1.7e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CAR22492.1 - 1e-05 25.6 0.0 2.7e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Fer4_12 PF13353.6 CAR22492.1 - 0.0077 16.5 0.0 0.02 15.1 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain DAGK_cat PF00781.24 CAR22492.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 CAR22493.1 - 5.5e-70 235.7 0.0 7.7e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22493.1 - 1.1e-32 113.3 0.0 1.5e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CAR22493.1 - 1.7e-10 41.4 0.6 5.7e-10 39.7 0.6 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CAR22493.1 - 6.9e-06 25.2 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAR22493.1 - 0.0008 18.8 0.1 0.0044 16.4 0.0 2.1 3 0 0 3 3 3 1 Kinase-like FTA2 PF13095.6 CAR22493.1 - 0.025 14.2 0.1 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CAR22493.1 - 0.051 12.9 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR22493.1 - 0.11 12.5 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3824 PF12868.7 CAR22493.1 - 0.56 10.9 3.9 1 10.0 3.9 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF2897 PF11446.8 CAR22493.1 - 1.8 8.5 7.7 4.3 7.3 7.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RRN3 PF05327.11 CAR22494.1 - 2.8e-187 623.7 10.1 3.3e-187 623.5 10.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 CAR22494.1 - 0.0049 15.2 1.0 0.0072 14.6 1.0 1.3 1 0 0 1 1 1 1 Nop14-like family Pes-10 PF07149.11 CAR22494.1 - 0.0064 15.6 12.1 0.03 13.4 6.0 2.3 2 0 0 2 2 2 2 Pes-10 Exonuc_VII_L PF02601.15 CAR22494.1 - 0.091 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SDA1 PF05285.12 CAR22494.1 - 1.2 8.5 9.2 2.4 7.5 9.2 1.5 1 0 0 1 1 1 0 SDA1 zf-MYND PF01753.18 CAR22495.1 - 2.7e-07 30.6 19.6 1.1e-06 28.6 19.6 2.1 1 1 0 1 1 1 1 MYND finger Vma12 PF11712.8 CAR22496.1 - 3.3e-39 134.2 0.1 4.5e-39 133.7 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Prenyltransf PF01255.19 CAR22497.1 - 1.4e-63 214.4 0.0 1.8e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Mito_carr PF00153.27 CAR22498.1 - 7e-59 195.8 5.1 6e-20 71.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 CAR22499.1 - 1.6e-20 73.0 8.5 8.9e-06 26.4 0.0 6.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22499.1 - 7.4e-06 26.2 0.0 1.8 8.9 0.0 5.0 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CAR22499.1 - 0.14 10.7 0.0 2 6.9 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain SRP9-21 PF05486.12 CAR22500.1 - 2.9e-16 59.6 0.4 2.9e-16 59.6 0.4 2.4 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) SPRY PF00622.28 CAR22501.1 - 4.1e-11 43.0 0.0 9.3e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 SPRY domain Aldose_epim PF01263.20 CAR22503.1 - 8.1e-44 150.1 0.1 9.8e-44 149.9 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.25 CAR22504.1 - 1.8e-41 142.2 0.0 2.8e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22504.1 - 1.9e-19 69.9 0.0 1.5e-18 67.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase AP_endonuc_2 PF01261.24 CAR22505.1 - 1.5e-34 119.3 0.0 2.1e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HpaB_N PF11794.8 CAR22505.1 - 0.041 13.5 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal XPG_N PF00752.17 CAR22506.1 - 6.1e-38 129.4 0.0 1.2e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CAR22506.1 - 1.7e-27 95.6 0.0 4.1e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CAR22506.1 - 1.8e-06 28.4 0.3 3.7e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 CAR22506.1 - 0.017 15.7 0.0 0.053 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain HHH_2 PF12826.7 CAR22506.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DNA_pol_lambd_f PF10391.9 CAR22506.1 - 0.12 12.2 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda 5_3_exonuc_N PF02739.16 CAR22506.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.8 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain BAF1_ABF1 PF04684.13 CAR22507.1 - 8.4e-183 609.4 12.6 1.8e-150 502.7 0.0 2.9 1 1 1 2 2 2 2 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 CAR22507.1 - 0.02 14.9 0.3 0.04 13.9 0.3 1.4 1 0 0 1 1 1 0 MuDR family transposase Spt20 PF12090.8 CAR22507.1 - 1.7 8.2 19.8 3 7.4 19.8 1.3 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 CAR22507.1 - 1.7 8.6 5.8 2.6 8.0 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CAR22507.1 - 2.9 7.6 10.9 4.7 7.0 10.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 baeRF_family10 PF18854.1 CAR22507.1 - 3.3 8.0 14.1 6.3 7.0 14.1 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 Pex14_N PF04695.13 CAR22507.1 - 5.6 7.6 11.5 11 6.6 11.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.9 CAR22507.1 - 6.2 5.3 11.9 9.3 4.7 11.9 1.2 1 0 0 1 1 1 0 Macoilin family MMR1 PF08505.10 CAR22507.1 - 6.5 7.0 13.1 10 6.3 13.1 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein mRNA_stabil PF13929.6 CAR22508.1 - 5.6e-95 317.6 0.1 1e-94 316.8 0.0 1.4 2 0 0 2 2 2 1 mRNA stabilisation RsfS PF02410.15 CAR22508.1 - 9.3e-20 70.9 0.0 3.4e-19 69.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation KTI12 PF08433.10 CAR22509.1 - 2.3e-94 315.9 0.7 2.6e-94 315.7 0.7 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Miff PF05644.11 CAR22509.1 - 0.0042 16.7 0.9 0.0067 16.1 0.9 1.2 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff AAA_18 PF13238.6 CAR22509.1 - 0.0067 17.0 0.1 0.028 15.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR22509.1 - 0.0068 16.7 0.2 0.11 12.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR22509.1 - 0.0099 16.0 0.0 0.035 14.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CAR22509.1 - 0.046 14.2 0.0 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rhomboid_N PF12122.8 CAR22509.1 - 0.065 13.4 0.7 0.43 10.8 0.0 2.6 3 1 1 4 4 4 0 Cytoplasmic N-terminal domain of rhomboid serine protease Mob_Pre PF01076.19 CAR22509.1 - 0.082 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Plasmid recombination enzyme AAA_16 PF13191.6 CAR22509.1 - 0.1 13.0 0.2 0.92 9.9 0.0 2.3 2 2 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 CAR22509.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CDC48_N PF02359.18 CAR22509.1 - 0.14 12.4 0.8 16 5.8 0.2 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain RasGEF_N PF00618.20 CAR22509.1 - 0.17 12.1 1.3 1.1 9.5 0.2 2.4 2 1 0 2 2 2 0 RasGEF N-terminal motif Ribosomal_L10 PF00466.20 CAR22509.1 - 0.31 11.2 1.9 4.6 7.4 0.1 2.9 2 1 1 3 3 3 0 Ribosomal protein L10 MMR_HSR1 PF01926.23 CAR22510.1 - 1.4e-11 44.5 0.0 2.5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR22510.1 - 1.5e-06 28.3 0.5 0.0028 17.6 0.3 2.8 2 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CAR22510.1 - 0.0099 15.4 0.2 0.031 13.8 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 CAR22510.1 - 0.043 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CAR22510.1 - 0.052 13.1 0.1 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CAR22510.1 - 0.094 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 KaiC Dynamin_N PF00350.23 CAR22510.1 - 0.21 11.7 0.1 15 5.6 0.1 2.2 1 1 0 2 2 2 0 Dynamin family NADHdh PF00146.21 CAR22510.1 - 0.22 10.8 0.0 0.33 10.2 0.0 1.1 1 0 0 1 1 1 0 NADH dehydrogenase Hap4_Hap_bind PF10297.9 CAR22511.1 - 7.7e-08 32.2 8.2 2.3e-07 30.7 8.2 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 ZapB PF06005.12 CAR22511.1 - 0.039 14.4 1.1 0.094 13.2 1.1 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Cnn_1N PF07989.11 CAR22511.1 - 0.12 12.6 0.8 0.59 10.3 0.6 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 CAR22511.1 - 0.24 11.5 2.5 0.4 10.8 2.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor Herpes_BLRF2 PF05812.12 CAR22511.1 - 0.3 11.2 2.0 0.4 10.8 0.3 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DivIC PF04977.15 CAR22511.1 - 0.31 10.8 1.4 0.59 9.9 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator LRRFIP PF09738.9 CAR22511.1 - 3.9 6.9 5.7 3.1 7.2 0.1 2.8 3 0 0 3 3 3 0 LRRFIP family KAR9 PF08580.10 CAR22511.1 - 5.6 5.4 13.7 9.5 4.6 13.7 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SOR_SNZ PF01680.17 CAR22512.1 - 1.8e-104 348.0 8.2 2.3e-104 347.6 8.2 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CAR22512.1 - 2.8e-08 33.4 1.7 4.9e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 CAR22512.1 - 7.2e-05 22.0 1.4 0.46 9.5 0.0 3.1 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CAR22512.1 - 0.0077 15.7 0.1 0.089 12.2 0.0 2.4 3 0 0 3 3 3 1 Histidine biosynthesis protein TetR_C_27 PF17935.1 CAR22512.1 - 0.0084 16.2 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 CAR22512.1 - 0.02 14.1 0.2 0.18 11.0 0.0 2.3 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.15 CAR22512.1 - 0.031 13.7 1.3 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase TMP-TENI PF02581.17 CAR22512.1 - 0.04 13.2 1.7 0.32 10.3 0.1 2.8 2 2 2 4 4 4 0 Thiamine monophosphate synthase IGPS PF00218.21 CAR22512.1 - 0.087 12.0 0.1 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase MCM_lid PF17855.1 CAR22512.1 - 0.15 12.5 0.3 1 9.8 0.0 2.2 2 0 0 2 2 2 0 MCM AAA-lid domain Peptidase_S66C PF17676.1 CAR22512.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 LD-carboxypeptidase C-terminal domain Milton PF12448.8 CAR22512.1 - 0.18 11.9 0.0 0.55 10.3 0.0 1.8 1 1 1 2 2 2 0 Kinesin associated protein SNO PF01174.19 CAR22513.1 - 4.8e-67 225.5 0.0 6.2e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CAR22513.1 - 7.8e-08 32.1 0.0 2.1e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 CAR22513.1 - 0.003 17.3 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 ThiJ/PfpI family-like GATase PF00117.28 CAR22513.1 - 0.011 15.5 0.0 0.04 13.7 0.0 1.8 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 CAR22513.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 DJ-1_PfpI PF01965.24 CAR22513.1 - 0.014 15.2 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family DUF4154 PF13689.6 CAR22513.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 YfiR/HmsC-like UPF0180 PF03698.13 CAR22513.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) ArsD PF06953.11 CAR22513.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.4 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD SMC_ScpB PF04079.16 CAR22514.1 - 0.088 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Segregation and condensation complex subunit ScpB Drc1-Sld2 PF11719.8 CAR22515.1 - 1.4e-30 107.3 34.9 3e-16 60.0 24.1 3.2 1 1 1 2 2 2 2 DNA replication and checkpoint protein Porin_OmpG_1_2 PF16946.5 CAR22515.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 OMPG-porin 1 family UTP15_C PF09384.10 CAR22516.1 - 2.2e-43 147.5 0.8 3.4e-43 146.9 0.8 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CAR22516.1 - 7.1e-16 58.3 2.9 0.028 15.3 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22516.1 - 1.9e-06 28.1 0.0 0.0029 17.9 0.0 4.1 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR22517.1 - 2.4e-12 47.1 18.9 0.48 11.4 0.4 9.8 9 1 1 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22517.1 - 1.5e-10 41.2 0.3 0.49 10.7 0.0 6.9 3 3 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR22517.1 - 0.00018 20.3 0.4 0.1 11.2 0.1 2.6 2 0 0 2 2 2 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 CAR22517.1 - 0.00018 20.9 0.0 0.002 17.4 0.0 2.2 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Adeno_E3A PF05248.12 CAR22517.1 - 0.0048 16.9 0.0 11 6.1 0.1 3.3 3 0 0 3 3 3 1 Adenovirus E3A WD40_like PF17005.5 CAR22517.1 - 0.14 11.5 0.1 11 5.3 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain eIF2A PF08662.11 CAR22517.1 - 0.19 11.6 0.5 20 5.0 0.0 3.9 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A CRC_subunit PF08624.10 CAR22518.1 - 2.3e-53 180.2 0.0 4.1e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit YL1 PF05764.13 CAR22518.1 - 0.39 10.8 6.9 0.56 10.3 6.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_M41 PF01434.18 CAR22519.1 - 9.8e-66 221.2 0.7 1.6e-65 220.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CAR22519.1 - 9.4e-43 145.8 0.0 2.8e-42 144.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR22519.1 - 1.6e-13 50.2 0.0 6.2e-13 48.3 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 CAR22519.1 - 1.3e-08 35.2 0.1 4.4e-08 33.4 0.1 1.9 1 1 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.6 CAR22519.1 - 0.0013 19.2 0.3 0.0067 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CAR22519.1 - 0.0016 18.5 0.2 0.011 15.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CAR22519.1 - 0.0028 16.9 0.0 0.0059 15.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CAR22519.1 - 0.0041 16.9 0.0 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR22519.1 - 0.012 16.0 1.0 0.13 12.7 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 CAR22519.1 - 0.022 14.9 0.0 0.07 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF1117 PF06547.12 CAR22519.1 - 0.039 14.5 0.9 3 8.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) SMBP PF16785.5 CAR22519.1 - 0.053 13.7 3.1 0.065 13.5 0.7 2.2 2 0 0 2 2 2 0 Small metal-binding protein CARD PF00619.21 CAR22519.1 - 0.06 13.4 0.4 0.14 12.2 0.4 1.6 1 0 0 1 1 1 0 Caspase recruitment domain AAA_22 PF13401.6 CAR22519.1 - 0.063 13.6 0.1 2.2 8.5 0.1 2.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CAR22519.1 - 0.099 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CAR22519.1 - 0.16 12.5 2.3 1 9.9 0.0 3.0 2 2 0 2 2 2 0 AAA domain DUF3774 PF12609.8 CAR22519.1 - 0.3 12.1 1.5 1.1 10.3 1.5 2.0 1 0 0 1 1 1 0 Wound-induced protein RNase_J_C PF17770.1 CAR22519.1 - 0.37 11.9 2.4 1.2 10.2 1.2 2.5 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain DUF1640 PF07798.11 CAR22519.1 - 3.3 7.7 8.8 2.8 7.9 4.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) MFS_1 PF07690.16 CAR22520.1 - 1.4e-37 129.5 42.8 2.3e-37 128.8 39.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR22520.1 - 7e-16 58.1 5.6 7e-16 58.1 5.6 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 CAR22520.1 - 0.92 8.3 30.6 0.012 14.5 2.9 4.1 2 2 2 4 4 4 0 MFS_1 like family CoA_binding_3 PF13727.6 CAR22520.1 - 6.7 6.7 9.4 0.34 10.9 1.0 3.0 3 0 0 3 3 3 0 CoA-binding domain Macro_2 PF14519.6 CAR22521.1 - 4.3e-79 265.8 0.0 5.1e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 CAR22521.1 - 6.6e-05 22.9 0.0 0.00014 21.9 0.0 1.5 2 0 0 2 2 2 1 Macro domain Aminotran_1_2 PF00155.21 CAR22522.1 - 1.5e-83 281.0 0.0 1.7e-83 280.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.22 CAR22524.1 - 2.1e-65 218.5 0.2 1.8e-33 115.2 0.2 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CAR22524.1 - 4.2e-16 59.4 0.0 8.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CAR22524.1 - 2.6e-10 40.3 0.0 6e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CAR22524.1 - 6.8e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 CAR22524.1 - 0.0012 17.7 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Peptidase_M18 PF02127.15 CAR22525.1 - 1e-144 482.5 0.0 1.2e-144 482.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pkinase PF00069.25 CAR22526.1 - 1.3e-71 241.1 0.0 3.2e-71 239.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22526.1 - 1.2e-37 129.6 0.0 2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CAR22526.1 - 0.001 18.7 0.2 0.0036 16.9 0.1 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CAR22526.1 - 0.0053 16.7 0.0 0.025 14.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR22526.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAR22526.1 - 0.014 14.7 0.0 0.044 13.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like ADH_N PF08240.12 CAR22527.1 - 2e-29 101.7 0.5 3.7e-29 100.8 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR22527.1 - 6.9e-25 87.5 0.3 1.1e-24 86.8 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR22527.1 - 3.4e-08 34.6 0.0 6.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CAR22527.1 - 0.1 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Utp11 PF03998.13 CAR22529.1 - 3e-66 223.8 34.7 3.5e-66 223.6 34.7 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 CAR22529.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 AAA_lid_2 PF17863.1 CAR22530.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain AAA_lid_7 PF17867.1 CAR22530.1 - 0.15 12.2 0.0 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 Midasin AAA lid domain PIR PF00399.19 CAR22531.1 - 2.2e-39 132.2 75.8 2.8e-08 33.1 10.0 5.8 5 0 0 5 5 5 5 Yeast PIR protein repeat DctP PF03480.13 CAR22531.1 - 0.15 11.4 1.4 13 5.0 0.1 2.1 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 DUF572 PF04502.13 CAR22533.1 - 5e-43 148.0 20.0 8.8e-43 147.2 20.0 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) HlyD_2 PF12700.7 CAR22533.1 - 0.078 11.7 7.9 0.14 10.9 7.9 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Mu-like_Com PF10122.9 CAR22533.1 - 0.12 11.8 0.4 0.69 9.4 0.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com EMC3_TMCO1 PF01956.16 CAR22533.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.7 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Allexi_40kDa PF05549.11 CAR22533.1 - 0.22 11.0 3.3 0.4 10.2 3.3 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein zf_UBZ PF18439.1 CAR22533.1 - 0.36 10.5 2.3 3.8 7.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ACC PF17848.1 CAR22533.1 - 0.5 10.5 3.1 0.41 10.8 0.3 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain V_ATPase_I PF01496.19 CAR22533.1 - 0.94 7.3 9.1 1.1 7.0 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.8 CAR22533.1 - 0.99 8.5 8.4 1.5 8.0 8.4 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 EMP24_GP25L PF01105.24 CAR22533.1 - 1.9 8.4 6.3 0.35 10.8 2.4 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD LMBR1 PF04791.16 CAR22533.1 - 2.7 6.8 3.5 3 6.7 3.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PA26 PF04636.13 CAR22533.1 - 6 5.7 8.3 8.3 5.2 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hydrolase_4 PF12146.8 CAR22534.1 - 3.5e-49 167.2 0.0 4.4e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAR22534.1 - 1.1e-19 71.1 0.0 1e-17 64.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR22534.1 - 1.1e-12 49.0 0.0 1.4e-12 48.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CAR22534.1 - 0.0055 16.2 0.1 0.35 10.3 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 CAR22534.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family LCAT PF02450.15 CAR22534.1 - 0.02 14.1 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 CAR22534.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 CAR22534.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.4 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 CAR22534.1 - 0.09 12.4 0.0 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CAR22534.1 - 0.15 11.9 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CAR22534.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold MBR1 PF17058.5 CAR22535.1 - 7.9e-20 72.0 17.3 1.7e-16 61.1 2.3 3.0 2 1 1 3 3 3 2 Mitochondrial biogenesis regulation protein 1 UPF1_Zn_bind PF09416.10 CAR22536.1 - 1.5e-63 213.3 13.1 1.6e-63 213.2 10.3 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CAR22536.1 - 6.2e-59 199.0 0.0 1.1e-58 198.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR22536.1 - 2e-49 168.7 4.2 4.3e-26 92.3 0.6 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CAR22536.1 - 2.6e-27 94.9 0.0 6e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CAR22536.1 - 2.1e-16 60.2 0.0 7.9e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR22536.1 - 3.5e-13 50.1 0.0 6.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CAR22536.1 - 1.9e-05 24.1 0.3 0.00043 19.6 0.0 2.8 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CAR22536.1 - 5.1e-05 23.4 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CAR22536.1 - 0.00016 21.3 0.3 0.04 13.4 0.0 2.8 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 CAR22536.1 - 0.00021 21.1 0.0 0.53 10.0 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CAR22536.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.14 CAR22536.1 - 0.01 15.0 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DEAD PF00270.29 CAR22536.1 - 0.012 15.3 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 CAR22536.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 CAR22536.1 - 0.049 13.3 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 CAR22536.1 - 0.051 12.5 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain T2SSE PF00437.20 CAR22536.1 - 0.064 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CAR22536.1 - 0.082 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain HEM4 PF02602.15 CAR22536.1 - 0.099 12.0 0.0 0.24 10.7 0.1 1.6 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD RasGAP PF00616.19 CAR22537.1 - 4e-41 141.0 1.4 5.7e-40 137.3 1.4 2.3 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CAR22537.1 - 0.00031 21.0 0.0 0.00071 19.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain CRAL_TRIO PF00650.20 CAR22538.1 - 7.5e-37 126.5 0.0 9.4e-37 126.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CAR22538.1 - 0.0017 18.6 0.0 0.0022 18.2 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 CAR22538.1 - 0.077 13.2 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) AAA PF00004.29 CAR22539.1 - 3.2e-11 43.8 0.0 8.1e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CAR22539.1 - 4e-07 30.1 0.1 4.1e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CAR22539.1 - 5.6e-05 23.2 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CAR22539.1 - 0.00018 21.8 0.1 0.00087 19.6 0.0 2.2 2 0 0 2 2 2 1 AAA C-terminal domain AAA_16 PF13191.6 CAR22539.1 - 0.00034 21.0 0.0 0.0013 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CAR22539.1 - 0.00042 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAR22539.1 - 0.002 18.4 0.2 0.036 14.4 0.0 2.9 2 1 1 3 3 3 1 AAA domain DNA_pol3_delta PF06144.13 CAR22539.1 - 0.0045 16.8 0.1 0.012 15.4 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_33 PF13671.6 CAR22539.1 - 0.01 16.0 0.0 0.034 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAR22539.1 - 0.017 15.7 0.0 0.088 13.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 CAR22539.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IPT PF01745.16 CAR22539.1 - 0.057 12.8 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase Zeta_toxin PF06414.12 CAR22539.1 - 0.087 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin bZIP_1 PF00170.21 CAR22540.1 - 1.8e-05 24.7 17.8 4e-05 23.6 16.3 2.1 2 0 0 2 2 2 1 bZIP transcription factor KASH_CCD PF14662.6 CAR22540.1 - 0.0093 15.8 8.8 0.015 15.1 8.8 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 CAR22540.1 - 0.015 15.4 16.9 0.015 15.4 16.9 2.4 2 1 1 3 3 3 0 Basic region leucine zipper Pinin_SDK_memA PF04696.13 CAR22540.1 - 0.067 13.3 13.4 0.1 12.7 13.4 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region V_ATPase_I PF01496.19 CAR22540.1 - 2.9 5.7 5.9 4.4 5.1 5.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 2OG-FeII_Oxy_3 PF13640.6 CAR22541.1 - 2e-08 35.0 0.1 3.6e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sod_Fe_N PF00081.22 CAR22541.1 - 0.1 13.1 0.0 0.43 11.1 0.0 1.9 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain CUE PF02845.16 CAR22542.1 - 9.3e-05 22.0 0.0 0.0039 16.9 0.0 2.4 2 0 0 2 2 2 1 CUE domain Smr PF01713.21 CAR22542.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 Smr domain CENP-C_C PF11699.8 CAR22543.1 - 2.5e-25 88.5 0.2 4.3e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 CAR22543.1 - 9e-07 29.7 0.3 9e-07 29.7 0.3 3.4 4 1 0 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 CAR22543.1 - 9.6e-06 25.2 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Cupin domain UCR_14kD PF02271.16 CAR22543.1 - 0.029 14.3 1.0 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex 14kD subunit AT_hook PF02178.19 CAR22543.1 - 0.075 12.9 5.3 0.28 11.2 5.3 2.1 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.25 CAR22544.1 - 8.6e-73 244.9 0.0 1.3e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22544.1 - 2.4e-46 158.1 0.0 4.5e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CAR22544.1 - 5.1e-24 84.4 0.1 2e-23 82.5 0.1 2.2 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CAR22544.1 - 2.6e-05 23.7 0.0 5.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR22544.1 - 9.4e-05 21.4 0.8 0.00025 19.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CAR22544.1 - 0.17 11.8 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.25 CAR22545.1 - 2.8e-69 233.9 0.7 5e-69 233.1 0.7 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TA0956 PF11513.8 CAR22545.1 - 0.026 14.8 0.0 0.75 10.0 0.0 2.9 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 Fes1 PF08609.10 CAR22545.1 - 0.048 14.5 0.7 0.81 10.6 0.0 3.1 2 1 1 3 3 3 0 Nucleotide exchange factor Fes1 Bin3 PF06859.12 CAR22545.1 - 0.06 14.0 0.2 0.5 11.0 0.1 2.4 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) DUF4175 PF13779.6 CAR22545.1 - 2.1 6.2 4.3 2.9 5.7 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RL10P_insert PF17777.1 CAR22546.1 - 9.4e-17 60.8 0.0 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CAR22546.1 - 5.1e-16 58.7 0.0 8.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RE_XamI PF09572.10 CAR22546.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 XamI restriction endonuclease Ribosomal_S2 PF00318.20 CAR22548.1 - 1.4e-70 236.9 0.0 7.1e-70 234.6 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 TRAM_LAG1_CLN8 PF03798.16 CAR22549.1 - 1.3e-39 136.0 24.3 1.3e-39 136.0 24.3 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CAR22549.1 - 8.9e-23 79.7 0.2 8.9e-23 79.7 0.2 1.9 2 0 0 2 2 2 1 TRAM1-like protein Ninjurin PF04923.12 CAR22549.1 - 0.22 11.5 1.7 0.31 11.0 0.2 1.9 2 0 0 2 2 2 0 Ninjurin VHS PF00790.19 CAR22550.1 - 1.4e-31 109.2 0.2 3.4e-31 108.0 0.2 1.7 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CAR22550.1 - 4.6e-16 58.2 0.0 8.7e-16 57.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR22550.1 - 2.7e-14 52.8 0.0 4.5e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR22550.1 - 1.9e-13 49.9 0.3 7.5e-13 47.9 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain Hrs_helical PF12210.8 CAR22550.1 - 0.00045 20.7 5.0 0.0012 19.3 0.1 2.8 2 1 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Tnp_DNA_bind PF14706.6 CAR22550.1 - 0.041 13.7 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 0 Transposase DNA-binding GAT PF03127.14 CAR22550.1 - 0.074 13.4 0.2 0.074 13.4 0.2 2.5 2 1 0 2 2 2 0 GAT domain ALMT PF11744.8 CAR22550.1 - 4.9 5.9 9.4 12 4.6 9.4 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter F-actin_cap_A PF01267.17 CAR22551.1 - 9.7e-79 264.5 0.5 1.1e-78 264.3 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit NTP_transf_6 PF06042.11 CAR22551.1 - 0.046 13.6 0.2 0.1 12.5 0.2 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase Ribosomal_L10 PF00466.20 CAR22551.1 - 0.098 12.8 0.1 9.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L10 DUF2207 PF09972.9 CAR22552.1 - 0.0043 15.9 0.2 0.0044 15.9 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) ParD_like PF11903.8 CAR22552.1 - 0.011 15.8 0.2 0.32 11.1 0.0 2.2 2 0 0 2 2 2 0 ParD-like antitoxin of type II bacterial toxin-antitoxin system Ribosomal_L14e PF01929.17 CAR22553.1 - 3.3e-33 114.0 1.1 6.1e-33 113.1 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CAR22553.1 - 6.8e-05 22.7 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 KOW motif TFIIS_M PF07500.14 CAR22554.1 - 4.4e-20 72.2 1.8 1.4e-19 70.7 1.8 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 CAR22554.1 - 1.1e-09 38.0 8.8 2.7e-09 36.8 8.8 1.7 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 CAR22554.1 - 8.9e-09 35.4 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 SPOC domain zf-CW PF07496.15 CAR22554.1 - 0.009 16.0 2.6 0.009 16.0 2.6 2.5 3 0 0 3 3 3 1 CW-type Zinc Finger PHD_Oberon PF07227.11 CAR22554.1 - 0.024 14.5 2.2 0.055 13.3 2.2 1.6 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein Prok-RING_1 PF14446.6 CAR22554.1 - 1.2 9.1 8.6 5.9 6.9 7.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CAR22554.1 - 1.8 8.7 11.9 0.82 9.8 8.1 2.4 2 1 1 3 3 3 0 PHD-finger Elf1 PF05129.13 CAR22554.1 - 1.9 8.6 6.0 3.7 7.7 2.7 2.8 1 1 0 2 2 2 0 Transcription elongation factor Elf1 like PAP2_3 PF14378.6 CAR22555.1 - 1.5e-24 86.8 8.1 1.5e-24 86.8 8.1 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CAR22555.1 - 5.2e-11 42.5 3.0 5.2e-11 42.5 3.0 2.3 2 1 0 2 2 2 1 PAP2 superfamily Ribosomal_S6 PF01250.17 CAR22556.1 - 1.8e-26 92.2 0.0 2.4e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Snf7 PF03357.21 CAR22557.1 - 2.3e-32 112.0 23.6 2.9e-32 111.7 20.9 1.9 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 CAR22557.1 - 1.7e-06 28.0 9.0 2.5e-06 27.5 9.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SPACA9 PF15120.6 CAR22557.1 - 0.0032 17.3 4.9 0.0043 16.9 4.9 1.2 1 0 0 1 1 1 1 Sperm acrosome-associated protein 9 DEPP PF15343.6 CAR22557.1 - 0.022 14.8 7.6 0.027 14.6 6.5 1.6 1 1 0 1 1 1 0 Decidual protein induced by progesterone family Remorin_C PF03763.13 CAR22557.1 - 0.23 11.4 12.4 0.34 10.8 11.4 1.8 1 1 0 1 1 1 0 Remorin, C-terminal region YlqD PF11068.8 CAR22557.1 - 2.3 8.6 20.8 4.1 7.8 13.4 2.2 1 1 1 2 2 2 0 YlqD protein DUF948 PF06103.11 CAR22557.1 - 4.1 7.7 7.5 8.8 6.7 0.3 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1002 PF06207.11 CAR22557.1 - 4.2 6.8 11.6 0.13 11.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) Prefoldin_2 PF01920.20 CAR22557.1 - 4.7 7.2 15.3 3.1 7.8 1.4 2.5 2 0 0 2 2 2 0 Prefoldin subunit DUF3958 PF13125.6 CAR22557.1 - 6 7.1 18.0 0.6 10.3 9.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) TMPIT PF07851.13 CAR22557.1 - 9.8 5.3 11.5 7.3 5.7 10.2 1.4 1 1 0 1 1 1 0 TMPIT-like protein APS_kinase PF01583.20 CAR22558.1 - 1.2e-72 242.9 0.0 1.5e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CAR22558.1 - 1.2e-05 25.5 0.0 3e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR22558.1 - 0.0004 20.9 0.0 0.00062 20.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CAR22558.1 - 0.00044 19.9 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.10 CAR22558.1 - 0.0006 19.4 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CPT PF07931.12 CAR22558.1 - 0.018 14.9 1.0 0.47 10.3 1.0 2.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 CAR22558.1 - 0.05 14.1 0.0 0.087 13.3 0.0 1.3 1 1 0 1 1 1 0 ABC transporter PRK PF00485.18 CAR22558.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 CAR22558.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_M PF01031.20 CAR22559.1 - 1.7e-99 332.6 0.4 3.2e-99 331.7 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CAR22559.1 - 3.8e-57 193.0 0.1 9.3e-57 191.7 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CAR22559.1 - 2.1e-28 98.3 4.1 5.6e-28 96.9 4.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CAR22559.1 - 0.00011 22.3 0.7 0.00044 20.3 0.7 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CAR22559.1 - 0.17 12.3 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PAP_central PF04928.17 CAR22560.1 - 2.1e-111 370.9 0.0 2.7e-111 370.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CAR22560.1 - 3.2e-53 179.9 2.1 3.2e-53 179.9 0.1 1.9 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CAR22560.1 - 8.4e-14 51.6 0.0 2.1e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CAR22560.1 - 0.0049 16.9 0.3 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 CAR22560.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain DUF4850 PF16142.5 CAR22560.1 - 0.012 15.1 0.6 0.047 13.2 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4850) Tox-PL-2 PF15643.6 CAR22560.1 - 0.095 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Papain fold toxin 2 Oxysterol_BP PF01237.18 CAR22561.1 - 1.2e-85 287.6 0.2 8.6e-84 281.5 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF5466 PF17554.2 CAR22561.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5466) PPTA PF01239.22 CAR22562.1 - 0.079 12.7 5.8 8.8 6.2 1.0 3.5 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat Ribosomal_L50 PF10501.9 CAR22563.1 - 1.3e-27 96.1 0.0 4.8e-27 94.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal subunit 39S LAMTOR PF15454.6 CAR22564.1 - 1.1e-22 80.4 5.8 1.8e-22 79.7 5.8 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF3552 PF12072.8 CAR22564.1 - 0.031 13.7 1.0 0.045 13.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Bromodomain PF00439.25 CAR22565.1 - 1.5e-25 89.1 4.8 8.3e-18 64.3 0.3 2.7 2 0 0 2 2 2 2 Bromodomain Malt_amylase_C PF16657.5 CAR22565.1 - 0.064 13.4 0.1 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Cadherin-like PF12733.7 CAR22565.1 - 0.069 13.7 0.1 0.41 11.2 0.0 2.2 2 0 0 2 2 2 0 Cadherin-like beta sandwich domain QCR10 PF09796.9 CAR22566.1 - 1.7e-27 95.2 0.2 2.1e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) adh_short PF00106.25 CAR22567.1 - 1.5e-87 292.2 7.8 7.5e-45 152.8 0.7 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAR22567.1 - 6.4e-70 235.3 2.9 4.3e-36 124.6 0.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CAR22567.1 - 1.9e-31 108.2 0.0 3.9e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CAR22567.1 - 2.4e-30 105.8 2.1 5.2e-15 55.8 0.3 2.4 2 0 0 2 2 2 2 KR domain 3HCDH_N PF02737.18 CAR22567.1 - 0.026 14.4 2.8 3.5 7.5 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CAR22567.1 - 0.43 11.0 3.0 10 6.6 0.1 3.3 3 0 0 3 3 3 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 CAR22567.1 - 0.44 10.6 2.7 1 9.4 0.1 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PglL_A PF15864.5 CAR22567.1 - 1.2 9.0 7.9 5.5 6.8 1.0 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase Adap_comp_sub PF00928.21 CAR22568.1 - 7e-35 120.7 0.0 9.2e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ntox28 PF15605.6 CAR22568.1 - 0.025 14.8 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial toxin 28 SNF5 PF04855.12 CAR22569.1 - 3.8e-49 167.6 4.6 3.8e-49 167.6 4.6 4.5 2 2 1 3 3 3 1 SNF5 / SMARCB1 / INI1 Macoilin PF09726.9 CAR22569.1 - 0.12 11.0 27.5 0.2 10.2 27.5 1.4 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CAR22569.1 - 5.1 4.1 38.8 7.3 3.6 38.8 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CAR22569.1 - 8 4.4 40.2 12 3.9 40.2 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2370 PF10176.9 CAR22570.1 - 4.1e-79 265.4 0.0 5e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.27 CAR22571.1 - 4.3e-60 199.6 2.0 9e-21 73.6 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR22571.1 - 0.018 14.2 5.2 5.1 6.2 0.1 3.3 1 1 2 3 3 3 0 Gammaproteobacterial serine protease Tim17 PF02466.19 CAR22571.1 - 0.83 10.1 5.7 24 5.3 0.0 3.5 1 1 2 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 CAR22572.1 - 3.6e-59 196.7 0.8 5e-20 71.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.7 CAR22572.1 - 0.83 9.8 3.5 9.4 6.4 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) ThiF PF00899.21 CAR22573.1 - 1.7e-44 152.1 0.0 2.4e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CAR22573.1 - 0.00017 21.8 0.7 0.0019 18.5 0.7 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CAR22573.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 CAR22573.1 - 0.023 14.3 0.6 0.042 13.4 0.6 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 CAR22573.1 - 0.025 15.2 0.1 0.091 13.4 0.1 2.0 1 0 0 1 1 1 0 PglD N-terminal domain TrkA_N PF02254.18 CAR22573.1 - 0.027 14.7 0.1 0.054 13.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 CAR22573.1 - 0.056 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TFIIE_alpha PF02002.17 CAR22574.1 - 1e-29 102.5 0.6 2.2e-29 101.4 0.1 1.9 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 CAR22574.1 - 7e-09 35.1 0.2 7e-09 35.1 0.2 2.4 2 0 0 2 2 2 1 TFIIB zinc-binding HTH_37 PF13744.6 CAR22574.1 - 0.0087 16.0 0.1 1.3 9.1 0.0 3.1 2 0 0 2 2 2 1 Helix-turn-helix domain MFS_1 PF07690.16 CAR22575.1 - 1.6e-32 112.8 27.2 4.6e-32 111.3 25.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR22575.1 - 9e-15 54.5 22.2 2.2e-14 53.2 4.3 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Malic_M PF03949.15 CAR22576.1 - 7.4e-86 287.6 0.1 2.3e-85 286.0 0.1 1.7 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 CAR22576.1 - 1.1e-61 207.8 0.0 3.2e-61 206.3 0.0 1.7 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain OPT PF03169.15 CAR22577.1 - 6.2e-158 527.2 44.3 7.4e-158 526.9 44.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein NIF PF03031.18 CAR22578.1 - 1.2e-50 171.4 0.0 1.6e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Leuk-A4-hydro_C PF09127.11 CAR22578.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal zf-H2C2_2 PF13465.6 CAR22579.1 - 1.3e-10 41.1 7.6 9.7e-07 29.0 0.2 3.2 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CAR22579.1 - 4.4e-10 39.4 11.2 1.1e-05 25.6 0.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR22579.1 - 1.3e-07 31.8 11.1 0.0029 18.3 3.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CAR22579.1 - 0.012 16.0 0.4 0.012 16.0 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CAR22579.1 - 0.084 12.9 8.8 0.29 11.2 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 CAR22579.1 - 0.55 9.9 0.1 0.55 9.9 0.1 2.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 CAR22579.1 - 0.72 9.7 13.4 0.58 10.0 1.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 CAR22579.1 - 2.7 8.4 7.9 34 4.9 4.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Acetyltransf_1 PF00583.25 CAR22580.1 - 2.3e-05 24.6 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAR22580.1 - 0.0065 16.9 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAR22580.1 - 0.061 13.3 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.6 CAR22581.1 - 0.00036 21.1 15.9 0.065 14.1 4.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR22581.1 - 0.00076 19.8 16.9 0.02 15.4 4.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 CAR22581.1 - 0.024 14.9 1.1 0.024 14.9 1.1 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CAR22581.1 - 0.033 14.3 1.2 0.07 13.3 1.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain TFIIA PF03153.13 CAR22581.1 - 0.42 10.6 35.3 0.72 9.8 35.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 CAR22581.1 - 0.75 10.3 12.8 1 9.9 2.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CAR22581.1 - 1.1 9.3 7.4 2.8 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Actin_micro PF17003.5 CAR22581.1 - 1.9 7.6 3.2 1.5 7.9 0.2 1.9 1 1 1 2 2 2 0 Putative actin-like family SKA1 PF07160.12 CAR22581.1 - 2.9 7.7 8.2 5.5 6.8 8.2 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Dicty_REP PF05086.12 CAR22581.1 - 4.3 5.2 9.6 6 4.7 9.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Presenilin PF01080.17 CAR22581.1 - 7.5 5.2 6.7 12 4.6 6.7 1.2 1 0 0 1 1 1 0 Presenilin Cg6151-P PF10233.9 CAR22582.1 - 9.5e-40 135.4 12.8 1.2e-39 135.1 12.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF962 PF06127.11 CAR22582.1 - 4.1 7.5 6.6 11 6.1 6.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF962) zinc_ribbon_6 PF14599.6 CAR22583.1 - 4.7e-24 84.2 4.7 4.7e-24 84.2 4.7 4.2 4 1 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 CAR22583.1 - 2.7e-16 59.8 23.9 2.7e-16 59.8 23.9 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 CAR22583.1 - 1.3e-08 35.0 7.3 1.3e-08 35.0 7.3 5.3 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR22583.1 - 2.3e-05 24.1 8.6 2.3e-05 24.1 8.6 4.4 3 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR22583.1 - 0.00022 21.0 3.3 0.00022 21.0 3.3 5.0 4 2 1 5 5 5 2 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CAR22583.1 - 0.0004 20.4 6.8 0.0004 20.4 6.8 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAR22583.1 - 0.00074 19.4 10.0 0.00074 19.4 10.0 5.9 4 3 1 5 5 5 1 zinc-RING finger domain HMG_box PF00505.19 CAR22584.1 - 4.7e-35 119.8 12.4 9.9e-20 70.7 6.1 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR22584.1 - 6.6e-18 65.1 17.7 1.5e-10 41.5 4.5 3.1 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.12 CAR22584.1 - 1.7e-11 43.9 0.0 0.0001 22.2 0.0 2.7 2 0 0 2 2 2 2 CHDNT (NUC034) domain EIIBC-GUT_N PF03612.14 CAR22584.1 - 0.007 16.1 1.6 0.017 14.9 1.6 1.7 1 0 0 1 1 1 1 Sorbitol phosphotransferase enzyme II N-terminus dsDNA_bind PF01984.20 CAR22584.1 - 0.41 10.9 13.2 1 9.6 13.2 1.7 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Cyt-b5 PF00173.28 CAR22585.1 - 6.5e-22 77.5 0.0 1.2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGP PF03214.13 CAR22585.1 - 0.17 11.0 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide Cu_amine_oxid PF01179.20 CAR22587.1 - 5.8e-148 493.2 2.0 6.9e-148 492.9 2.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain dsDNA_bind PF01984.20 CAR22588.1 - 1.4e-23 83.3 2.3 1.7e-23 83.0 2.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TetR_C_11 PF16859.5 CAR22588.1 - 0.28 11.5 10.6 0.46 10.8 9.7 1.9 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain EF-1_beta_acid PF10587.9 CAR22588.1 - 0.36 11.3 0.2 0.36 11.3 0.2 2.8 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region PHD PF00628.29 CAR22589.1 - 3.4e-13 49.2 23.0 7.7e-10 38.5 11.2 2.8 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.6 CAR22589.1 - 1.1 8.9 13.1 2.1 8.0 2.9 3.3 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 CAR22589.1 - 3.6 7.6 20.3 0.49 10.3 0.8 3.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cnd1 PF12717.7 CAR22590.1 - 0.00059 19.9 0.1 1.6 8.7 0.0 4.5 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAR22590.1 - 0.00086 19.4 0.2 14 6.3 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat Adaptin_N PF01602.20 CAR22590.1 - 0.0016 17.1 0.2 0.026 13.1 0.1 2.4 2 0 0 2 2 2 1 Adaptin N terminal region NUDIX_4 PF14815.6 CAR22590.1 - 0.1 12.6 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 NUDIX domain Form_Nir_trans PF01226.17 CAR22591.1 - 1.8e-58 197.7 27.8 2.2e-58 197.4 27.8 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Vac14_Fab1_bd PF12755.7 CAR22592.1 - 0.013 16.0 0.7 0.34 11.5 0.0 3.3 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region AA_permease PF00324.21 CAR22593.1 - 1.1e-111 373.8 47.8 1.4e-111 373.5 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR22593.1 - 8.4e-31 107.2 54.3 1e-30 106.9 54.3 1.1 1 0 0 1 1 1 1 Amino acid permease BRAP2 PF07576.12 CAR22594.1 - 6.2e-26 90.5 0.0 1.4e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CAR22594.1 - 5.7e-21 74.6 4.2 1.3e-20 73.5 4.2 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CAR22594.1 - 1.6e-08 34.8 10.5 1.6e-08 34.8 10.5 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR22594.1 - 1.1e-06 28.3 10.0 1.1e-06 28.3 10.0 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAR22594.1 - 3.3e-05 24.1 7.8 0.00011 22.5 7.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CAR22594.1 - 3.8e-05 23.6 7.5 0.00015 21.7 7.5 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CAR22594.1 - 9.8e-05 22.0 4.3 9.8e-05 22.0 4.3 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CAR22594.1 - 0.00014 21.6 6.2 0.00014 21.6 6.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR22594.1 - 0.00015 21.5 9.4 0.00015 21.5 9.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR22594.1 - 0.00018 21.4 8.4 0.00018 21.4 8.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Atg14 PF10186.9 CAR22594.1 - 0.015 14.4 8.0 0.025 13.7 8.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_4 PF14570.6 CAR22594.1 - 0.017 14.9 7.8 0.042 13.7 7.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CAR22594.1 - 0.019 15.0 3.9 0.056 13.5 3.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CAR22594.1 - 0.034 14.3 5.5 0.15 12.2 5.6 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FlaC_arch PF05377.11 CAR22594.1 - 0.061 13.7 1.0 0.061 13.7 1.0 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Prok-RING_4 PF14447.6 CAR22594.1 - 0.15 12.0 21.1 0.13 12.2 12.3 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 EB1 PF03271.17 CAR22594.1 - 0.23 11.7 1.4 0.65 10.3 1.4 1.8 1 0 0 1 1 1 0 EB1-like C-terminal motif DUF1664 PF07889.12 CAR22594.1 - 1.9 8.5 12.0 0.28 11.2 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pribosyl_synth PF14572.6 CAR22595.1 - 6.8e-41 140.3 3.3 2.7e-35 122.1 1.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CAR22595.1 - 7.9e-38 129.0 0.0 2.2e-37 127.6 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CAR22595.1 - 8.2e-17 61.2 1.0 3.1e-16 59.3 0.8 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAR22595.1 - 0.074 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HAD_2 PF13419.6 CAR22596.1 - 8.4e-20 71.6 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR22596.1 - 8.3e-11 42.6 0.0 2.2e-10 41.2 0.0 1.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CAR22596.1 - 0.025 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR22596.1 - 0.044 14.2 0.0 0.057 13.8 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-rbx1 PF12678.7 CAR22597.1 - 2.7e-09 37.2 4.9 5e-09 36.3 4.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAR22597.1 - 2.7e-08 34.0 7.9 9.4e-08 32.3 7.9 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CAR22597.1 - 9.1e-07 28.7 3.2 1.6e-06 28.0 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CAR22597.1 - 2.2e-06 27.4 2.7 2.2e-06 27.4 2.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR22597.1 - 4.6e-06 26.3 5.6 0.0003 20.4 1.3 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 CAR22597.1 - 6e-05 22.8 5.8 0.00011 21.9 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR22597.1 - 0.0001 22.1 3.5 0.00022 21.0 3.5 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CAR22597.1 - 0.0002 21.3 4.4 0.00055 19.9 4.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CAR22597.1 - 0.00056 19.5 2.3 0.0012 18.4 2.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CAR22597.1 - 0.00079 19.4 1.3 0.0018 18.3 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CAR22597.1 - 0.0014 18.5 5.3 0.0039 17.0 5.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CAR22597.1 - 0.06 13.5 5.1 0.23 11.6 5.1 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-P11 PF03854.14 CAR22597.1 - 1.9 8.2 5.3 0.65 9.7 2.1 1.8 2 0 0 2 2 2 0 P-11 zinc finger zf-C3H2C3 PF17122.5 CAR22597.1 - 3.1 7.9 6.8 1.2 9.3 1.7 2.7 3 0 0 3 3 3 0 Zinc-finger UDPGP PF01704.18 CAR22598.1 - 5.1e-185 615.0 0.0 6.1e-185 614.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Zn_clus PF00172.18 CAR22599.1 - 1.7e-09 37.6 10.2 3.1e-09 36.8 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FBA_2 PF07735.17 CAR22599.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 F-box associated OTU PF02338.19 CAR22600.1 - 1.3e-25 90.3 0.7 4.3e-25 88.7 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CAR22600.1 - 2.7e-05 23.8 3.5 0.00031 20.3 0.0 3.0 3 0 0 3 3 3 1 Peptidase C65 Otubain Striatin PF08232.12 CAR22600.1 - 1.5 9.4 17.9 2.8 8.5 17.9 1.5 1 0 0 1 1 1 0 Striatin family YchF-GTPase_C PF06071.13 CAR22601.1 - 2.3e-30 104.6 0.0 4.4e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CAR22601.1 - 2.4e-16 59.8 0.1 5.6e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR22601.1 - 0.00029 20.4 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CAR22601.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 TGS domain Ribosomal_S10 PF00338.22 CAR22602.1 - 7.7e-25 87.0 0.6 9.3e-25 86.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Cnl2_NKP2 PF09447.10 CAR22602.1 - 0.062 13.5 0.9 0.11 12.7 0.4 1.6 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Retrotrans_gag PF03732.17 CAR22602.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.5 1 1 0 1 1 1 0 Retrotransposon gag protein DUF1688 PF07958.11 CAR22603.1 - 5.4e-153 509.7 0.0 6e-153 509.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SSF PF00474.17 CAR22604.1 - 7.9e-18 64.5 31.8 1.1e-17 64.1 31.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family DUF3087 PF11286.8 CAR22604.1 - 0.24 10.9 0.7 1 8.8 0.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF2207 PF09972.9 CAR22604.1 - 0.24 10.1 0.0 0.24 10.1 0.0 4.4 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Lung_7-TM_R PF06814.13 CAR22605.1 - 3.1e-84 282.7 22.5 3.7e-84 282.4 22.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Nfu_N PF08712.11 CAR22606.1 - 1.3e-26 92.4 0.0 4.5e-26 90.7 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CAR22606.1 - 3.3e-26 91.2 0.1 5.9e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 CAR22606.1 - 0.00067 19.7 0.5 0.0015 18.6 0.5 1.6 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus gpW PF02831.15 CAR22606.1 - 0.034 14.1 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 gpW BA14K PF07886.11 CAR22606.1 - 0.22 11.4 0.3 0.37 10.7 0.3 1.3 1 0 0 1 1 1 0 BA14K-like protein Pterin_4a PF01329.19 CAR22607.1 - 4.1e-26 91.0 0.0 4.9e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Adap_comp_sub PF00928.21 CAR22608.1 - 6.6e-64 215.8 0.4 9.7e-64 215.3 0.4 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAR22608.1 - 0.0077 16.2 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Opi1 PF08618.10 CAR22610.1 - 8.6e-35 120.8 5.3 1.2e-21 77.5 0.1 3.2 1 1 1 3 3 3 3 Transcription factor Opi1 Tom22 PF04281.13 CAR22610.1 - 0.34 10.7 9.0 0.048 13.4 4.2 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 FAM176 PF14851.6 CAR22610.1 - 2.9 7.6 9.0 22 4.7 7.1 2.4 2 0 0 2 2 2 0 FAM176 family SID-1_RNA_chan PF13965.6 CAR22610.1 - 3.8 5.8 6.7 2.1 6.6 4.0 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Snf7 PF03357.21 CAR22611.1 - 2.4e-28 98.9 16.8 2.4e-28 98.9 16.8 1.7 2 0 0 2 2 2 1 Snf7 PAS_7 PF12860.7 CAR22611.1 - 0.0033 17.6 3.0 0.21 11.8 0.1 2.7 2 1 0 3 3 3 2 PAS fold DUF1574 PF07611.11 CAR22611.1 - 0.2 11.0 6.8 0.36 10.1 6.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1574) CLU PF13236.6 CAR22612.1 - 3e-64 216.9 0.1 8e-64 215.5 0.1 1.8 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CAR22612.1 - 2.4e-36 125.4 1.8 2.8e-36 125.2 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 CAR22612.1 - 1.1e-17 64.2 0.6 4.6e-17 62.2 0.1 2.5 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 CAR22612.1 - 3e-09 37.1 1.9 1.4e-05 25.3 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAR22612.1 - 5.4e-07 29.3 1.2 4.4e-05 23.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR22612.1 - 0.00043 20.2 1.0 0.4 10.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR22612.1 - 0.0016 18.2 0.6 0.87 9.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF727 PF05303.12 CAR22612.1 - 0.036 14.1 0.1 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF727) TPR_8 PF13181.6 CAR22612.1 - 0.05 13.8 4.2 0.24 11.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat FliT PF05400.13 CAR22612.1 - 0.22 12.4 3.3 0.25 12.2 1.1 2.2 2 0 0 2 2 2 0 Flagellar protein FliT DUF2593 PF10767.9 CAR22613.1 - 0.031 14.4 8.0 0.025 14.7 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) CPP1-like PF11833.8 CAR22613.1 - 1.6 8.4 10.4 8.6 6.0 3.0 3.7 3 1 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like BUD22 PF09073.10 CAR22614.1 - 7.8e-80 269.3 40.3 7.8e-80 269.3 40.3 1.6 1 1 1 2 2 2 1 BUD22 p450 PF00067.22 CAR22615.1 - 3.6e-55 187.5 0.1 4.6e-55 187.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF5314 PF17241.2 CAR22615.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5314) Spc42p PF11544.8 CAR22616.1 - 1e-25 89.5 3.5 1e-25 89.5 3.5 2.0 2 0 0 2 2 2 1 Spindle pole body component Spc42p Csm1_N PF18504.1 CAR22616.1 - 0.015 15.6 2.8 0.015 15.6 2.8 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain Troponin PF00992.20 CAR22616.1 - 0.022 15.1 0.2 0.022 15.1 0.2 1.9 2 0 0 2 2 2 0 Troponin DivIVA PF05103.13 CAR22616.1 - 0.066 13.3 2.4 0.18 11.9 0.8 2.0 2 0 0 2 2 2 0 DivIVA protein UPF0242 PF06785.11 CAR22616.1 - 0.077 13.1 5.6 0.15 12.1 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus tRNA_U5-meth_tr PF05958.11 CAR22616.1 - 0.091 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Phage_GP20 PF06810.11 CAR22616.1 - 0.44 10.4 6.1 0.77 9.5 0.6 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 SlyX PF04102.12 CAR22616.1 - 5.1 7.8 12.0 8.1 7.1 1.1 4.1 3 2 1 4 4 4 0 SlyX DUF4559 PF15112.6 CAR22616.1 - 5.4 6.6 6.4 0.4 10.3 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) KilA-N PF04383.13 CAR22617.1 - 9.6e-05 22.2 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Fungal_trans PF04082.18 CAR22618.1 - 1.2e-19 70.4 1.5 2e-19 69.7 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR22618.1 - 9.3e-08 32.1 10.6 9.3e-08 32.1 10.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_primase_lrg PF04104.14 CAR22619.1 - 1.8e-89 299.7 0.1 3.2e-89 298.9 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Adap_comp_sub PF00928.21 CAR22619.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Adaptor complexes medium subunit family Amino_oxidase PF01593.24 CAR22620.1 - 1e-63 216.3 0.0 1.3e-63 215.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CAR22620.1 - 4.3e-14 52.5 0.2 9.4e-14 51.4 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CAR22620.1 - 8e-07 29.0 0.1 1.9e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CAR22620.1 - 3.3e-06 26.5 0.1 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR22620.1 - 9.7e-06 25.0 0.5 0.0021 17.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CAR22620.1 - 1.2e-05 24.7 0.2 2.3e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CAR22620.1 - 1.9e-05 24.1 0.1 0.0013 18.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CAR22620.1 - 2.1e-05 23.5 0.4 0.0068 15.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 CAR22620.1 - 0.00014 21.1 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 CAR22620.1 - 0.0011 18.3 0.1 0.0019 17.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 CAR22620.1 - 0.0015 17.7 0.6 0.0063 15.6 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CAR22620.1 - 0.0023 18.4 1.0 0.0048 17.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR22620.1 - 0.0087 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CAR22620.1 - 0.046 13.7 0.3 9.8 6.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 CAR22620.1 - 0.052 12.8 0.1 0.098 11.9 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CAR22620.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Copper-fist PF00649.18 CAR22621.1 - 1.8e-20 72.1 2.8 4e-20 71.0 2.8 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain UQ_con PF00179.26 CAR22622.1 - 1e-48 164.6 0.0 1.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR22622.1 - 0.11 12.2 0.1 0.43 10.3 0.0 2.0 1 1 0 2 2 2 0 Prokaryotic E2 family B Glyco_hydro_76 PF03663.14 CAR22623.1 - 5.3e-160 532.9 23.9 6.1e-160 532.7 23.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF2347 PF09804.9 CAR22624.1 - 5.1e-77 259.2 0.2 7.1e-77 258.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 CAR22624.1 - 4.1e-13 49.9 3.2 3.1e-06 27.4 0.0 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4484) Avl9 PF09794.9 CAR22624.1 - 8.3e-09 34.6 0.2 1.3e-07 30.7 0.2 2.1 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CAR22624.1 - 2.3e-05 24.3 0.0 7.2e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Stabilization of polarity axis BLI1 PF17324.2 CAR22625.1 - 2.7e-28 98.8 4.7 3.3e-28 98.6 4.7 1.0 1 0 0 1 1 1 1 BLOC-1 interactor 1 BLOC1_2 PF10046.9 CAR22625.1 - 0.0013 19.0 2.2 0.0029 17.9 2.2 1.8 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tektin PF03148.14 CAR22625.1 - 0.0043 15.9 1.0 0.035 12.9 0.5 1.9 2 0 0 2 2 2 1 Tektin family DUF1664 PF07889.12 CAR22625.1 - 0.024 14.7 1.3 0.049 13.7 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 CAR22625.1 - 0.031 13.6 0.5 0.035 13.4 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 CAR22625.1 - 0.041 14.1 1.5 0.051 13.8 1.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DOG1 PF14144.6 CAR22625.1 - 0.13 12.5 0.1 0.67 10.2 0.0 2.1 1 1 2 3 3 3 0 Seed dormancy control MnmE_helical PF12631.7 CAR22626.1 - 6e-41 140.9 0.2 7.7e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 CAR22626.1 - 3.8e-34 117.5 0.0 9.6e-34 116.2 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CAR22626.1 - 1.8e-23 82.8 0.2 5.9e-23 81.1 0.1 2.0 2 1 1 3 3 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR22626.1 - 4.2e-13 49.1 0.4 6.6e-13 48.5 0.4 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR22626.1 - 3.6e-08 33.5 0.2 0.0019 18.1 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CAR22626.1 - 3.3e-06 26.8 0.7 0.00044 19.9 0.3 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAR22626.1 - 5.5e-06 26.5 1.0 0.00046 20.3 1.0 2.7 1 1 0 1 1 1 1 Dynamin family Ras PF00071.22 CAR22626.1 - 6.8e-05 22.5 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CAR22626.1 - 0.00021 20.8 0.1 0.0022 17.5 0.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family cobW PF02492.19 CAR22626.1 - 0.00063 19.4 1.1 0.0051 16.4 0.4 2.2 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CAR22626.1 - 0.00099 19.3 0.0 0.0067 16.6 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CAR22626.1 - 0.0043 16.4 0.1 0.58 9.5 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 CAR22626.1 - 0.0068 16.9 0.3 0.025 15.1 0.1 1.9 1 1 0 1 1 1 1 ABC transporter AIG1 PF04548.16 CAR22626.1 - 0.0076 15.6 0.3 0.013 14.8 0.3 1.4 1 0 0 1 1 1 1 AIG1 family SRP54 PF00448.22 CAR22626.1 - 0.0087 15.7 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MMR_HSR1_Xtn PF16897.5 CAR22626.1 - 0.026 14.5 0.1 0.055 13.5 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain dsrm PF00035.26 CAR22628.1 - 1.3e-06 29.1 0.0 2.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CAR22628.1 - 0.00057 20.5 0.0 0.0012 19.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain RACo_linker PF17650.1 CAR22628.1 - 0.056 13.3 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 RACo linker region Pex2_Pex12 PF04757.14 CAR22630.1 - 1.3e-38 132.8 12.0 1.6e-38 132.6 12.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 CAR22630.1 - 9.6e-06 25.3 0.9 1.7e-05 24.6 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR22630.1 - 8.8e-05 22.3 0.2 0.00016 21.4 0.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAR22630.1 - 0.0021 18.1 3.1 0.0037 17.4 3.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CAR22630.1 - 0.0034 17.4 3.9 0.0064 16.5 3.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR22630.1 - 0.0045 16.8 0.5 0.0078 16.1 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR22630.1 - 0.019 15.3 0.5 0.035 14.4 0.5 1.4 1 0 0 1 1 1 0 Ring finger domain ADK_lid PF05191.14 CAR22630.1 - 0.076 13.0 2.2 2.7 8.0 0.2 2.6 2 0 0 2 2 2 0 Adenylate kinase, active site lid F_bP_aldolase PF01116.20 CAR22631.1 - 4.7e-90 301.9 0.0 5.3e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II TPP_enzyme_N PF02776.18 CAR22632.1 - 1e-30 106.6 0.1 2.1e-30 105.6 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR22632.1 - 9.6e-27 93.4 0.0 2.1e-25 89.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR22632.1 - 4.1e-12 46.1 0.1 1.1e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 CAR22632.1 - 0.19 11.9 0.8 26 5.0 0.0 2.8 3 0 0 3 3 3 0 OCC1 family DUF89 PF01937.19 CAR22633.1 - 1.6e-113 379.3 1.0 1.8e-113 379.1 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DWNN PF08783.11 CAR22634.1 - 6e-29 100.1 0.1 1.7e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 CAR22634.1 - 1.6e-07 31.0 7.0 3.3e-07 30.0 7.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.8 CAR22634.1 - 3.6e-06 26.7 1.0 7.6e-06 25.7 0.2 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CAR22634.1 - 0.00039 20.5 0.0 0.0017 18.5 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-CCHC PF00098.23 CAR22634.1 - 0.00067 19.6 3.3 0.0016 18.4 3.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 CAR22634.1 - 0.019 15.0 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle CpXC PF14353.6 CAR22634.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 CpXC protein zf-DNL PF05180.12 CAR22634.1 - 0.074 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 DNL zinc finger zf-MIZ PF02891.20 CAR22634.1 - 0.096 12.4 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-CCHC_5 PF14787.6 CAR22634.1 - 5.4 6.8 6.2 0.26 11.0 0.5 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger TFIIA_gamma_C PF02751.14 CAR22635.1 - 4.2e-25 87.6 3.3 6.6e-25 87.0 3.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CAR22635.1 - 1.1e-21 76.5 0.2 1.6e-21 76.0 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TAP42 PF04177.12 CAR22636.1 - 4.9e-81 272.3 15.5 5.5e-81 272.1 15.5 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4238 PF14022.6 CAR22636.1 - 0.028 13.9 0.2 0.045 13.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) PI-PLC-X PF00388.19 CAR22636.1 - 0.037 13.6 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Nup160 PF11715.8 CAR22637.1 - 1.7e-21 76.5 0.7 3.5e-21 75.5 0.7 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Hira PF07569.11 CAR22637.1 - 0.0041 16.9 0.1 0.0092 15.7 0.1 1.5 1 0 0 1 1 1 1 TUP1-like enhancer of split Striatin PF08232.12 CAR22638.1 - 1e-19 71.7 1.6 1e-19 71.7 1.6 3.9 3 1 1 4 4 4 1 Striatin family Mto2_bdg PF12808.7 CAR22638.1 - 0.0026 18.0 1.7 0.0026 18.0 1.7 2.2 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1192 PF06698.11 CAR22638.1 - 0.19 11.8 0.9 0.42 10.7 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Troponin PF00992.20 CAR22638.1 - 5.6 7.3 8.8 18 5.6 3.5 2.4 2 0 0 2 2 2 0 Troponin Androgen_recep PF02166.16 CAR22638.1 - 7.3 5.3 10.2 11 4.8 10.2 1.2 1 0 0 1 1 1 0 Androgen receptor TCTP PF00838.17 CAR22639.1 - 8.3e-73 244.2 1.1 9.3e-73 244.0 1.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mus7 PF09462.10 CAR22639.1 - 0.043 12.7 0.0 0.049 12.5 0.0 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family RcbX PF02341.15 CAR22639.1 - 0.094 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 RbcX protein adh_short PF00106.25 CAR22640.1 - 6.9e-34 117.0 0.0 6.6e-25 87.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAR22640.1 - 4.6e-23 82.0 0.1 5.2e-20 72.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR22640.1 - 1.7e-05 24.8 0.8 0.0048 16.8 0.1 3.0 2 1 0 3 3 3 1 KR domain Epimerase PF01370.21 CAR22640.1 - 0.031 13.7 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CUE PF02845.16 CAR22641.1 - 0.00014 21.4 0.9 0.00026 20.6 0.1 1.9 2 0 0 2 2 2 1 CUE domain UPF0203 PF05254.12 CAR22642.1 - 2.9e-27 94.7 3.5 3.4e-27 94.5 3.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 CAR22642.1 - 0.00064 19.9 0.3 0.00099 19.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 CAR22642.1 - 0.0022 18.0 2.9 0.018 15.1 1.3 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 CAR22642.1 - 0.18 12.2 1.0 0.57 10.6 1.1 1.7 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 CAR22642.1 - 0.38 11.1 3.2 9.9 6.6 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 CAR22642.1 - 1.1 9.6 7.7 2 8.7 1.2 2.2 1 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb DASH_Ask1 PF08655.10 CAR22643.1 - 5.9e-28 96.5 0.1 9.5e-28 95.9 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 CPSF73-100_C PF11718.8 CAR22643.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term NLPC_P60 PF00877.19 CAR22643.1 - 0.14 12.2 0.1 11 6.1 0.0 2.3 2 0 0 2 2 2 0 NlpC/P60 family Frag1 PF10277.9 CAR22644.1 - 7.5e-83 277.4 19.8 8.7e-83 277.2 19.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Eisosome1 PF12757.7 CAR22645.1 - 4.3e-29 101.3 2.2 4.3e-29 101.3 2.2 5.8 3 1 3 6 6 6 1 Eisosome protein 1 FCH PF00611.23 CAR22646.1 - 6.1e-13 48.9 2.8 1.1e-12 48.1 0.1 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 CAR22646.1 - 0.00025 20.9 0.1 0.00045 20.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Tup_N PF08581.10 CAR22646.1 - 0.037 14.3 2.5 0.096 13.0 1.6 2.3 1 1 0 1 1 1 0 Tup N-terminal SH3_2 PF07653.17 CAR22646.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 CAR22646.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DUF3037 PF11236.8 CAR22646.1 - 0.56 10.7 3.4 2.6 8.5 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3037) Histone PF00125.24 CAR22647.1 - 7.5e-40 136.3 7.0 8.6e-40 136.1 6.5 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CAR22647.1 - 0.002 18.2 1.4 0.0025 17.9 0.2 1.7 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CAR22647.1 - 0.004 17.5 0.1 0.0077 16.6 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein Actin PF00022.19 CAR22648.1 - 7.1e-20 71.0 0.4 2e-17 62.9 0.1 2.9 1 1 1 2 2 2 2 Actin SBF_like PF13593.6 CAR22649.1 - 4.5e-128 427.0 20.2 5.2e-128 426.7 20.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) YdjM PF04307.14 CAR22649.1 - 1.6 8.0 9.6 0.095 12.0 3.4 2.3 2 1 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Peptidase_S24 PF00717.23 CAR22650.1 - 1.1e-06 28.5 1.2 6.5e-06 26.0 1.2 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CAR22650.1 - 7.2e-05 22.6 0.1 0.02 14.7 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Rhodanese PF00581.20 CAR22651.1 - 4.3e-09 36.8 0.0 9.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 CAR22652.1 - 2.5e-38 132.0 0.0 2e-35 122.4 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22652.1 - 2.3e-17 63.2 0.0 5.1e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR22652.1 - 0.00057 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR22652.1 - 0.013 15.4 0.0 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR22652.1 - 0.017 13.9 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Herpes_UL87 PF03043.14 CAR22652.1 - 0.061 11.8 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL87 family ESM4 PF15952.5 CAR22652.1 - 0.23 11.9 1.4 7.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Enhancer of split M4 family zf-C2H2 PF00096.26 CAR22653.1 - 1.1e-11 44.5 16.1 3.6e-06 27.1 3.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR22653.1 - 3.8e-08 33.5 15.2 0.00097 19.8 4.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR22653.1 - 1.4e-07 31.6 21.2 4.1e-06 27.0 5.3 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CAR22653.1 - 3.9e-05 23.8 14.4 0.03 14.6 7.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CAR22653.1 - 6.4e-05 22.9 6.5 0.06 13.4 1.6 2.6 2 0 0 2 2 2 2 BED zinc finger zf-C2HE PF16278.5 CAR22653.1 - 0.0097 16.3 11.7 0.84 10.1 3.0 2.9 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 CAR22653.1 - 0.042 13.9 18.1 0.053 13.5 7.5 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-AN1 PF01428.16 CAR22653.1 - 0.061 13.5 2.6 5 7.4 0.3 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger zf-met PF12874.7 CAR22653.1 - 0.16 12.4 9.7 0.72 10.3 4.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CAR22653.1 - 0.18 12.1 5.7 0.39 11.0 5.7 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 CAR22653.1 - 1.8 8.5 4.8 0.5 10.3 0.6 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain GAGA PF09237.11 CAR22653.1 - 2.8 7.8 8.2 6.3 6.7 1.0 3.4 2 1 1 3 3 3 0 GAGA factor zf_C2H2_ZHX PF18387.1 CAR22653.1 - 3.5 7.3 6.7 3.9 7.2 0.4 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_5 PF13909.6 CAR22653.1 - 4.1 7.2 24.8 0.32 10.8 7.5 3.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CAR22653.1 - 4.2 7.2 7.5 1.7 8.4 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type HMA PF00403.26 CAR22655.1 - 7.3e-08 32.8 0.1 1.3e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 CAR22655.1 - 0.0049 17.0 0.0 0.0098 16.1 0.0 1.5 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CorA PF01544.18 CAR22656.1 - 5.9e-39 134.1 3.0 6e-23 81.6 0.2 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Ribosomal_L32p PF01783.23 CAR22656.1 - 0.087 13.1 2.0 0.29 11.4 2.0 1.9 1 0 0 1 1 1 0 Ribosomal L32p protein family PC4 PF02229.16 CAR22657.1 - 2e-22 78.6 0.0 3.1e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Aldo_ket_red PF00248.21 CAR22658.1 - 1e-45 156.2 0.0 1.4e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bap31 PF05529.12 CAR22659.1 - 3.1e-22 78.9 0.1 3.1e-22 78.9 0.1 1.6 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region APG6_N PF17675.1 CAR22659.1 - 0.009 16.5 8.5 0.013 16.0 8.5 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region Bap31_Bap29_C PF18035.1 CAR22659.1 - 0.014 15.4 9.1 0.029 14.4 9.1 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mit_proteolip PF08039.11 CAR22659.1 - 0.11 13.0 0.2 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF1043 PF06295.12 CAR22659.1 - 0.14 12.2 3.7 0.24 11.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DivIC PF04977.15 CAR22659.1 - 0.29 11.0 4.5 0.9 9.4 4.3 1.7 1 1 0 1 1 1 0 Septum formation initiator Spc7 PF08317.11 CAR22659.1 - 0.35 9.7 8.1 0.46 9.3 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 CAR22659.1 - 0.78 9.0 4.6 0.17 11.2 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ING PF12998.7 CAR22660.1 - 5.9e-23 81.4 0.0 1.3e-22 80.3 0.0 1.6 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CAR22660.1 - 8.2e-05 22.4 6.4 0.00014 21.7 6.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CAR22660.1 - 0.02 15.1 0.4 0.038 14.2 0.4 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 CAR22660.1 - 0.036 13.6 1.6 0.07 12.7 1.6 1.5 1 0 0 1 1 1 0 PHD-finger Ras PF00071.22 CAR22661.1 - 1.5e-56 190.5 0.1 1.9e-56 190.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR22661.1 - 7.5e-20 71.4 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR22661.1 - 1.2e-08 34.6 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR22661.1 - 0.00011 21.8 0.1 0.00039 20.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR22661.1 - 0.00035 20.5 0.8 1.1 9.2 0.2 2.5 1 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR22661.1 - 0.0025 17.9 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase HATPase_c PF02518.26 CAR22661.1 - 0.14 12.7 0.1 0.4 11.2 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DAD PF02109.16 CAR22662.1 - 3.9e-37 126.9 5.7 4.6e-37 126.7 5.7 1.1 1 0 0 1 1 1 1 DAD family Y_phosphatase2 PF03162.13 CAR22663.1 - 5.7e-56 188.6 0.0 6.7e-56 188.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR22663.1 - 2.6e-05 24.3 0.0 8.1e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DUF2002 PF09400.10 CAR22663.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) Y_phosphatase PF00102.27 CAR22663.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ApoO PF09769.9 CAR22665.1 - 5.2e-09 36.1 0.1 9.9e-05 22.3 0.0 3.0 3 0 0 3 3 3 2 Apolipoprotein O Aa_trans PF01490.18 CAR22666.1 - 3.1e-94 316.0 37.4 3.7e-94 315.7 37.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CAR22666.1 - 4.9e-05 22.4 47.3 0.00018 20.5 47.3 1.7 1 1 0 1 1 1 1 Amino acid permease YrhC PF14143.6 CAR22666.1 - 0.89 9.7 6.6 0.17 12.0 1.4 2.5 2 0 0 2 2 2 0 YrhC-like protein DNA_pol_B PF00136.21 CAR22667.1 - 9.3e-122 407.0 1.1 1.4e-121 406.5 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CAR22667.1 - 2.2e-65 219.9 3.3 4.5e-65 218.9 3.3 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CAR22667.1 - 1e-42 146.5 0.0 1.8e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CAR22667.1 - 5.7e-20 71.2 8.6 1.6e-19 69.7 8.6 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal zinc_ribbon_4 PF13717.6 CAR22667.1 - 0.031 14.2 0.7 3.2 7.7 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DNA_pol_B_2 PF03175.13 CAR22667.1 - 0.078 11.8 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral C1_4 PF07975.12 CAR22667.1 - 0.28 11.4 2.5 0.95 9.7 2.5 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 CAR22667.1 - 1.5 9.0 3.4 2.3 8.4 0.0 2.8 3 0 0 3 3 3 0 Zinc ribbon domain SNARE PF05739.19 CAR22668.1 - 1.4e-12 47.4 1.7 3e-12 46.3 1.7 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CAR22668.1 - 1.5e-06 28.5 12.7 3.2e-05 24.2 1.3 3.4 3 1 0 3 3 3 2 Syntaxin-like protein Synaptobrevin PF00957.21 CAR22668.1 - 0.00015 21.5 0.3 0.00034 20.3 0.3 1.6 1 0 0 1 1 1 1 Synaptobrevin Fusion_gly PF00523.18 CAR22668.1 - 0.018 13.3 1.1 0.032 12.5 0.7 1.4 1 1 0 1 1 1 0 Fusion glycoprotein F0 DUF5345 PF17280.2 CAR22668.1 - 0.018 15.0 1.4 0.031 14.2 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) S6PP_C PF08472.10 CAR22668.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Syntaxin PF00804.25 CAR22668.1 - 0.021 14.5 0.9 0.021 14.5 0.9 2.3 3 0 0 3 3 3 0 Syntaxin T2SSF PF00482.23 CAR22668.1 - 0.021 14.7 0.2 0.74 9.8 0.0 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F OppC_N PF12911.7 CAR22668.1 - 0.049 13.6 1.3 0.088 12.8 1.3 1.4 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Prominin PF05478.11 CAR22668.1 - 0.055 11.4 1.7 0.16 9.9 0.5 1.9 2 0 0 2 2 2 0 Prominin Rx_N PF18052.1 CAR22668.1 - 0.064 13.5 0.1 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 Rx N-terminal domain MCU PF04678.13 CAR22668.1 - 0.13 12.3 1.0 0.17 11.9 0.5 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter MMPL PF03176.15 CAR22668.1 - 0.23 10.4 2.4 0.37 9.7 2.4 1.4 1 1 0 1 1 1 0 MMPL family Orf78 PF06024.12 CAR22668.1 - 0.43 10.9 2.1 0.52 10.6 0.4 2.0 1 1 1 2 2 2 0 Orf78 (ac78) UPF0258 PF06789.12 CAR22668.1 - 2.9 8.0 5.6 12 6.1 4.8 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0258) Seryl_tRNA_N PF02403.22 CAR22668.1 - 6.5 7.0 7.7 1.9 8.7 2.9 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RAB3GAP2_N PF14655.6 CAR22669.1 - 0.099 11.9 2.2 0.17 11.1 2.2 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PspB PF06667.12 CAR22669.1 - 0.3 11.2 0.8 0.85 9.7 0.8 1.7 1 0 0 1 1 1 0 Phage shock protein B RGS PF00615.19 CAR22670.1 - 2.5e-11 43.9 0.0 4.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain HMGL-like PF00682.19 CAR22671.1 - 5.2e-91 304.8 0.0 8.3e-91 304.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CAR22671.1 - 3.2e-26 91.8 0.3 6.2e-26 90.9 0.3 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ribosomal_S5 PF00333.20 CAR22671.1 - 0.051 13.5 0.1 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Syja_N PF02383.18 CAR22672.1 - 7.5e-78 262.1 0.1 2.1e-77 260.6 0.1 1.8 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CAR22672.1 - 4.3e-13 49.3 0.0 6.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.16 CAR22673.1 - 6.9e-35 118.9 0.3 1.1e-34 118.2 0.3 1.3 1 0 0 1 1 1 1 YEATS family TFIIIC_sub6 PF10419.9 CAR22674.1 - 7.6e-22 77.0 0.0 1.5e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_Phos_1 PF00300.22 CAR22674.1 - 1.5e-17 63.9 0.0 4.9e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Maf PF02545.14 CAR22675.1 - 4.9e-34 117.6 0.0 5.8e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein RRM_1 PF00076.22 CAR22676.1 - 2.9e-18 65.4 0.0 5.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CAR22676.1 - 0.0091 15.9 0.1 0.27 11.2 0.1 2.5 2 1 0 2 2 2 1 RL domain Cyt-b5 PF00173.28 CAR22677.1 - 1.1e-25 89.6 0.1 1.3e-25 89.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CLASP_N PF12348.8 CAR22678.1 - 0.031 13.8 0.0 1.3 8.6 0.0 2.7 2 1 0 2 2 2 0 CLASP N terminal COG4 PF08318.12 CAR22678.1 - 0.058 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 COG4 transport protein Cnd1 PF12717.7 CAR22678.1 - 0.14 12.2 0.1 4 7.4 0.0 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DEAD PF00270.29 CAR22679.1 - 5.9e-49 166.2 0.0 3.1e-48 163.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR22679.1 - 8.9e-33 113.0 0.0 2.6e-32 111.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR22679.1 - 0.00055 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CAR22679.1 - 0.013 14.3 0.0 0.15 10.8 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 CAR22679.1 - 0.021 15.2 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 CAR22679.1 - 0.044 13.0 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF5335 PF17269.2 CAR22679.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) RNA_pol_L_2 PF13656.6 CAR22680.1 - 1.2e-33 114.7 0.1 3.1e-33 113.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CAR22680.1 - 3.3e-15 55.3 0.0 5.8e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Arginase PF00491.21 CAR22681.1 - 1.4e-74 251.1 0.0 1.6e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family EnY2 PF10163.9 CAR22681.1 - 0.16 12.3 0.1 0.75 10.2 0.1 2.0 2 0 0 2 2 2 0 Transcription factor e(y)2 PEX11 PF05648.14 CAR22682.1 - 1.7e-07 30.9 7.5 4.1e-06 26.4 2.5 3.5 2 2 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DASH_Dad3 PF08656.10 CAR22682.1 - 0.036 14.2 1.9 0.52 10.4 0.0 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF4745 PF15923.5 CAR22682.1 - 0.09 12.8 1.8 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) 2-Hacid_dh_C PF02826.19 CAR22683.1 - 2.2e-35 121.6 0.0 3.2e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR22683.1 - 0.00034 20.3 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Semialdhyde_dh PF01118.24 CAR22683.1 - 0.015 15.7 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TFIIA PF03153.13 CAR22684.1 - 5.4e-44 151.8 37.0 1.2e-26 94.7 8.2 2.9 1 1 2 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF3999 PF13163.6 CAR22684.1 - 0.015 14.6 2.5 0.023 13.9 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) Fungal_TACC PF12709.7 CAR22685.1 - 1.5e-30 105.5 12.1 1.5e-30 105.5 12.1 9.1 3 2 6 10 10 10 2 Fungal Transforming acidic coiled-coil (TACC) proteins BRE1 PF08647.11 CAR22685.1 - 0.0012 18.8 16.0 0.0012 18.8 16.0 8.2 3 2 3 7 7 7 3 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 CAR22685.1 - 0.002 17.1 18.7 0.002 17.1 18.7 5.5 1 1 3 5 5 5 4 Spc7 kinetochore protein Golgin_A5 PF09787.9 CAR22685.1 - 0.066 12.7 98.4 0.032 13.7 23.6 5.0 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF3618 PF12277.8 CAR22685.1 - 0.098 12.9 1.5 0.45 10.8 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) SAP PF02037.27 CAR22685.1 - 0.19 11.5 3.3 0.54 10.1 0.2 3.2 3 0 0 3 3 3 0 SAP domain Fez1 PF06818.15 CAR22685.1 - 0.31 11.5 90.8 0.21 12.0 17.9 5.4 1 1 5 6 6 6 0 Fez1 RhoGAP PF00620.27 CAR22686.1 - 9.2e-33 113.2 0.6 2e-32 112.1 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 CAR22686.1 - 1.3e-09 38.5 0.0 4.8e-09 36.7 0.0 2.1 1 0 0 1 1 1 1 PH domain PX PF00787.24 CAR22686.1 - 1.6e-06 28.1 0.1 5.2e-06 26.4 0.1 1.9 1 0 0 1 1 1 1 PX domain Csm1_N PF18504.1 CAR22686.1 - 0.0027 18.0 2.0 0.0077 16.5 2.0 1.7 1 0 0 1 1 1 1 Csm1 N-terminal domain Shugoshin_N PF07558.11 CAR22686.1 - 0.034 14.0 0.2 0.087 12.7 0.2 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PRKG1_interact PF15898.5 CAR22686.1 - 0.46 11.4 4.9 0.81 10.6 3.4 2.3 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain SKIP_SNW PF02731.15 CAR22686.1 - 0.89 9.2 7.3 0.25 11.0 0.3 3.0 3 0 0 3 3 3 0 SKIP/SNW domain BLOC1_2 PF10046.9 CAR22686.1 - 3.3 8.1 5.7 1.9 8.9 1.8 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LIAS_N PF16881.5 CAR22687.1 - 5.5e-24 84.7 0.9 1.2e-23 83.6 0.9 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CAR22687.1 - 2.5e-14 54.0 0.0 5e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Phyto-Amp PF15438.6 CAR22687.1 - 0.076 12.8 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma Spore_GerAC PF05504.11 CAR22687.1 - 0.18 12.0 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Hist_deacetyl PF00850.19 CAR22689.1 - 3.6e-54 184.3 0.6 2.5e-53 181.6 0.1 2.2 2 0 0 2 2 2 1 Histone deacetylase domain Chorion_2 PF03964.15 CAR22689.1 - 0.043 14.7 1.5 0.13 13.1 1.5 1.8 1 0 0 1 1 1 0 Chorion family 2 DFF40 PF09230.10 CAR22689.1 - 0.06 12.9 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa Peptidase_C14 PF00656.22 CAR22690.1 - 2.2e-64 217.8 0.2 2.9e-64 217.4 0.2 1.1 1 0 0 1 1 1 1 Caspase domain FapA PF03961.13 CAR22691.1 - 0.0003 19.5 8.1 0.0003 19.5 8.1 3.8 2 1 1 3 3 3 1 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 CAR22691.1 - 0.049 13.7 20.7 1.1 9.3 1.4 4.9 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 CAR22691.1 - 5.4 6.3 44.7 0.65 9.3 6.6 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) NUDIX PF00293.28 CAR22692.1 - 7.2e-31 107.0 0.0 1.1e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SpoU_methylase PF00588.19 CAR22693.1 - 8.2e-28 97.3 0.0 1.9e-27 96.1 0.0 1.6 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CAR22693.1 - 4.1e-13 49.4 0.0 1.1e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.18 CAR22694.1 - 1.4e-61 207.0 0.5 2.2e-61 206.4 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Mit_ribos_Mrp51 PF11709.8 CAR22695.1 - 5.7e-68 230.2 3.7 4.6e-67 227.2 3.7 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DEAD PF00270.29 CAR22696.1 - 2.4e-46 157.7 0.0 5.4e-46 156.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR22696.1 - 1e-31 109.5 0.0 2.3e-31 108.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR22696.1 - 0.0062 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR22696.1 - 0.02 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CAR22696.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Tfb2 PF03849.14 CAR22697.1 - 7.9e-141 469.1 3.0 1.1e-140 468.6 3.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CAR22697.1 - 4.3e-22 78.3 0.4 1.1e-21 77.0 0.4 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CAR22697.1 - 1.1e-05 25.6 0.0 2.4e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNA_pol_Rpb2_6 PF00562.28 CAR22698.1 - 5e-123 411.0 0.1 5e-123 411.0 0.1 1.8 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAR22698.1 - 2.6e-62 210.0 1.5 5e-62 209.0 1.5 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CAR22698.1 - 7.3e-43 146.4 3.8 2e-42 145.0 3.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CAR22698.1 - 1.1e-33 115.5 1.6 1.8e-33 114.8 0.2 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CAR22698.1 - 8.6e-27 93.2 1.8 1.5e-26 92.4 0.8 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CAR22698.1 - 1.8e-18 66.5 0.2 5.9e-18 64.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CAR22698.1 - 2.8e-11 43.8 0.2 1.1e-10 41.9 0.2 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF370 PF04025.12 CAR22698.1 - 0.15 12.2 1.4 0.48 10.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF370) Mei5 PF10376.9 CAR22699.1 - 6.7e-27 94.7 13.2 8.5e-27 94.4 13.2 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein SprA-related PF12118.8 CAR22699.1 - 0.022 13.9 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 SprA-related family DNA_primase_lrg PF04104.14 CAR22699.1 - 0.23 10.8 2.4 0.22 10.9 1.2 1.5 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit HAND PF09110.11 CAR22699.1 - 8.4 7.2 11.2 1.3 9.8 7.2 1.8 2 0 0 2 2 2 0 HAND DUF1451 PF07295.11 CAR22699.1 - 8.7 6.4 9.1 4 7.5 6.0 1.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain Noc2 PF03715.13 CAR22700.1 - 6.3e-128 426.2 0.9 6.3e-128 426.2 0.9 2.4 2 1 0 2 2 2 1 Noc2p family MMR_HSR1 PF01926.23 CAR22701.1 - 1.3e-08 34.9 0.0 2.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR22701.1 - 0.0074 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CAR22701.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CAR22701.1 - 0.037 13.6 0.0 5.1 6.6 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAR22701.1 - 0.05 13.1 0.2 0.14 11.6 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.6 CAR22701.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_DNA_bi PF02236.17 CAR22701.1 - 0.061 13.5 0.2 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain AAA_22 PF13401.6 CAR22701.1 - 0.081 13.2 0.1 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF3073 PF11273.8 CAR22701.1 - 0.13 13.0 0.1 0.27 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) APG6 PF04111.12 CAR22702.1 - 4.7e-66 222.1 0.0 8.2e-66 221.4 0.0 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CAR22702.1 - 4e-27 95.3 19.5 6.5e-27 94.7 19.5 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Vps51 PF08700.11 CAR22702.1 - 0.27 11.4 7.1 2.5 8.2 0.7 2.7 2 0 0 2 2 2 0 Vps51/Vps67 Tweety PF04906.13 CAR22702.1 - 0.31 9.7 1.8 0.57 8.8 1.8 1.4 1 0 0 1 1 1 0 Tweety YabA PF06156.13 CAR22702.1 - 0.82 10.3 5.2 2.4 8.8 5.2 1.8 1 0 0 1 1 1 0 Initiation control protein YabA Ribonuc_red_lgC PF02867.15 CAR22703.1 - 4.9e-181 602.8 0.0 6.3e-181 602.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CAR22703.1 - 2.8e-23 81.7 0.0 5.9e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain Ribonuclease_T2 PF00445.18 CAR22704.1 - 1.7e-39 135.9 1.0 2.3e-39 135.5 1.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Spc29 PF17082.5 CAR22705.1 - 1e-26 94.3 8.6 2.7e-26 92.9 8.6 1.7 1 1 0 1 1 1 1 Spindle Pole Component 29 SlyX PF04102.12 CAR22705.1 - 0.017 15.7 2.7 0.051 14.2 0.7 2.7 2 1 0 2 2 2 0 SlyX BLOC1_2 PF10046.9 CAR22705.1 - 0.09 13.1 0.1 1.3 9.4 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Y_phosphatase PF00102.27 CAR22706.1 - 1.7e-58 198.0 0.0 1e-57 195.4 0.0 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CAR22706.1 - 0.00013 22.0 0.0 0.00033 20.7 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CAR22706.1 - 0.00028 21.0 1.7 1.6 8.8 0.0 3.2 3 0 0 3 3 3 2 Inositol hexakisphosphate DSPc PF00782.20 CAR22706.1 - 0.0011 18.8 0.0 0.0045 16.8 0.0 2.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TMEM61 PF15105.6 CAR22706.1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 TMEM61 protein family PI_PP_I PF18363.1 CAR22706.1 - 0.045 13.9 0.2 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain IBN_N PF03810.19 CAR22707.1 - 4.1e-17 61.9 0.6 5.3e-14 51.9 0.1 3.2 2 0 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.12 CAR22707.1 - 0.00096 19.2 7.6 0.039 14.0 0.1 4.3 4 0 0 4 4 4 2 Exportin 1-like protein DUF1912 PF08930.10 CAR22707.1 - 0.029 14.5 0.8 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) IF3_N PF05198.16 CAR22707.1 - 0.2 11.9 0.4 0.72 10.2 0.1 2.1 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain VHS PF00790.19 CAR22707.1 - 0.81 9.5 3.3 8.1 6.3 0.0 4.0 4 0 0 4 4 4 0 VHS domain NAPRTase PF04095.16 CAR22708.1 - 6.5e-70 235.5 0.0 8.5e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CAR22708.1 - 3.6e-32 111.4 0.0 8.1e-32 110.2 0.0 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain AAA_21 PF13304.6 CAR22708.1 - 0.0087 15.9 0.3 0.013 15.3 0.3 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system WD40 PF00400.32 CAR22709.1 - 0.00014 22.5 8.1 0.0082 17.0 0.6 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22709.1 - 0.0025 18.0 0.2 34 4.8 0.0 5.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DCAF15_WD40 PF14939.6 CAR22709.1 - 0.03 14.0 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 DDB1-and CUL4-substrate receptor 15, WD repeat RNA_pol_N PF01194.17 CAR22710.1 - 6.4e-30 103.2 0.5 7.3e-30 103.1 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CAR22710.1 - 0.061 13.6 0.1 0.081 13.2 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Dynamin_N PF00350.23 CAR22711.1 - 8.9e-43 146.2 0.2 3e-42 144.5 0.2 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CAR22711.1 - 6.1e-06 26.3 0.1 9.4e-05 22.5 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 CAR22711.1 - 0.0019 17.5 8.0 0.33 10.1 0.0 3.5 3 0 0 3 3 3 2 Dynamin central region AAA_16 PF13191.6 CAR22711.1 - 0.029 14.8 0.4 0.2 12.0 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CAR22711.1 - 0.061 13.5 0.2 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CAR22711.1 - 0.18 11.1 3.5 0.85 8.9 0.3 2.8 2 1 0 2 2 2 0 AIG1 family DUF1140 PF06600.11 CAR22711.1 - 0.43 11.0 5.4 9.4 6.8 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) NOA36 PF06524.12 CAR22711.1 - 0.49 9.7 6.8 0.86 8.9 6.8 1.3 1 0 0 1 1 1 0 NOA36 protein Linker_histone PF00538.19 CAR22712.1 - 5.4e-24 84.4 2.9 1.6e-23 82.9 0.0 2.6 3 0 0 3 3 3 1 linker histone H1 and H5 family HJURP_mid PF12346.8 CAR22712.1 - 4.7 7.7 10.6 0.35 11.3 2.4 2.5 2 1 0 2 2 2 0 Holliday junction recognition protein-associated repeat TRF PF08558.10 CAR22713.1 - 1.2e-62 211.7 0.6 1.7e-62 211.2 0.6 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CAR22713.1 - 1.1e-06 28.7 1.2 3.1e-06 27.3 0.7 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR22713.1 - 0.0078 16.4 0.1 0.02 15.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.32 CAR22714.1 - 2.2e-28 97.9 16.6 6.5e-06 26.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22714.1 - 5.5e-09 36.2 0.2 0.26 11.6 0.0 5.2 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR22714.1 - 0.0038 17.1 0.5 1.4 8.8 0.1 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR22714.1 - 0.0093 15.0 0.8 6.7 5.6 0.0 3.4 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein YEATS PF03366.16 CAR22715.1 - 5e-18 64.8 0.0 9.8e-18 63.9 0.0 1.5 1 0 0 1 1 1 1 YEATS family YEATS PF03366.16 CAR22716.1 - 1.2e-19 70.1 0.1 1.8e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CAR22716.1 - 2.2e-06 27.8 0.1 3.8e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YqeY PF09424.10 CAR22717.1 - 5.3e-24 84.9 2.2 6.2e-24 84.7 2.2 1.2 1 0 0 1 1 1 1 Yqey-like protein GRAB PF10375.9 CAR22718.1 - 2.9e-07 30.1 1.1 7.2e-07 28.9 1.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Spc7 PF08317.11 CAR22718.1 - 0.0011 17.9 75.8 0.0027 16.6 23.4 3.3 1 1 2 3 3 3 2 Spc7 kinetochore protein TolA_bind_tri PF16331.5 CAR22718.1 - 0.0015 18.6 3.0 0.0015 18.6 3.0 6.0 1 1 5 6 6 4 2 TolA binding protein trimerisation TMF_DNA_bd PF12329.8 CAR22718.1 - 0.0047 16.9 9.5 0.0047 16.9 9.5 6.4 1 1 4 6 6 5 2 TATA element modulatory factor 1 DNA binding Uso1_p115_C PF04871.13 CAR22718.1 - 0.0051 17.2 18.9 0.0051 17.2 18.9 5.3 1 1 3 5 5 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 CAR22718.1 - 0.016 15.3 26.7 0.016 15.3 26.7 5.2 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 CAR22718.1 - 0.019 15.0 15.1 0.019 15.0 15.1 4.5 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 CAR22718.1 - 0.084 13.4 91.1 0.11 13.1 23.7 4.2 1 1 2 3 3 3 0 Apg6 coiled-coil region GAS PF13851.6 CAR22718.1 - 0.51 9.7 80.3 0.15 11.4 13.2 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 CAR22718.1 - 1.2 8.6 69.6 7 6.1 5.3 4.2 1 1 2 3 3 3 0 Intermediate filament protein MbeD_MobD PF04899.12 CAR22718.1 - 2.1 8.5 29.7 0.13 12.4 3.7 5.2 3 2 2 5 5 5 0 MbeD/MobD like Fez1 PF06818.15 CAR22718.1 - 9 6.7 75.7 0.71 10.3 29.1 3.4 1 1 2 3 3 3 0 Fez1 RFC1 PF08519.12 CAR22719.1 - 1.3e-61 207.4 0.9 4.5e-61 205.6 0.3 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CAR22719.1 - 4.9e-11 43.2 0.0 1.6e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CAR22719.1 - 1.4e-10 41.4 0.0 4.1e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 CAR22719.1 - 2.9e-05 24.1 0.0 7.7e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CAR22719.1 - 0.00035 20.3 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CAR22719.1 - 0.0022 18.5 0.0 0.0067 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CAR22719.1 - 0.0037 17.6 0.0 0.0037 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA C-terminal domain AAA_16 PF13191.6 CAR22719.1 - 0.0048 17.3 0.0 0.017 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CAR22719.1 - 0.0058 16.7 0.0 0.039 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR22719.1 - 0.0062 16.8 0.0 0.049 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR22719.1 - 0.023 14.9 0.0 0.023 14.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 CAR22719.1 - 0.027 14.9 3.1 0.078 13.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAR22719.1 - 0.029 14.7 0.0 0.1 13.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CAR22719.1 - 0.03 14.0 0.0 0.099 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain DPPIV_N PF00930.21 CAR22720.1 - 2.5e-82 276.5 1.3 3.3e-82 276.1 1.3 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CAR22720.1 - 9.5e-49 165.7 0.1 1.9e-48 164.7 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CAR22720.1 - 0.00027 21.6 0.0 0.00069 20.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR22720.1 - 0.0013 18.0 0.0 0.2 10.9 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 CAR22720.1 - 0.0014 18.4 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 CAR22720.1 - 0.0014 18.3 0.4 0.027 14.1 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CAR22720.1 - 0.0018 18.1 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 CAR22720.1 - 0.049 12.1 0.0 0.31 9.5 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DLH PF01738.18 CAR22720.1 - 0.058 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.9 CAR22720.1 - 0.073 12.6 0.0 0.66 9.4 0.0 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase Ribosomal_L5e PF17144.4 CAR22721.1 - 3.6e-82 274.2 0.3 5.2e-82 273.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CAR22721.1 - 1.8e-31 108.9 5.2 1.8e-31 108.9 5.2 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DAG_kinase_N PF14513.6 CAR22721.1 - 0.0049 17.1 0.6 0.0049 17.1 0.6 1.6 2 0 0 2 2 2 1 Diacylglycerol kinase N-terminus NAC PF01849.18 CAR22721.1 - 0.019 15.0 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NAC domain Ribosomal_L18p PF00861.22 CAR22721.1 - 0.029 14.7 1.0 0.057 13.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Com_YlbF PF06133.11 CAR22721.1 - 0.031 14.9 1.9 0.073 13.7 1.9 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Thr_synth_N PF14821.6 CAR22721.1 - 0.11 12.7 0.3 0.81 9.9 0.0 2.5 2 1 1 3 3 3 0 Threonine synthase N terminus CtaG_Cox11 PF04442.14 CAR22724.1 - 3.2e-60 202.6 0.0 4.6e-60 202.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.18 CAR22725.1 - 8.4e-05 22.6 8.4 0.00018 21.6 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.21 CAR22726.1 - 0.00033 20.3 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Mito_carr PF00153.27 CAR22727.1 - 1.7e-63 210.6 1.7 7.1e-24 83.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CAR22727.1 - 0.011 16.1 1.7 0.057 13.8 1.7 2.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF2407_C PF13373.6 CAR22728.1 - 2.1e-35 121.9 1.1 4.7e-35 120.8 1.1 1.6 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CAR22728.1 - 4.7e-16 59.2 1.9 2.3e-13 50.6 0.2 2.4 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain MTP18 PF10558.9 CAR22729.1 - 1.4e-72 243.2 0.0 1.7e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) RNA_pol_Rpb8 PF03870.15 CAR22730.1 - 9.2e-45 152.2 0.0 1e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CAR22730.1 - 0.043 13.9 0.2 2.4 8.2 0.0 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G NifU_N PF01592.16 CAR22731.1 - 2.1e-56 189.6 0.1 2.5e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_2 PF07723.13 CAR22732.1 - 0.0034 18.0 0.9 0.62 10.8 0.0 3.5 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_6 PF13516.6 CAR22732.1 - 0.14 12.3 7.2 4.3 7.7 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat DUF1691 PF07950.11 CAR22733.1 - 1.4e-24 86.9 0.8 3.6e-17 63.0 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF2938 PF11158.8 CAR22733.1 - 0.00078 18.9 0.1 0.0013 18.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2938) PHD PF00628.29 CAR22734.1 - 5.8e-11 42.1 8.1 5.8e-11 42.1 8.1 2.4 3 0 0 3 3 3 1 PHD-finger WD40 PF00400.32 CAR22735.1 - 0.00017 22.3 4.4 0.45 11.5 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CAR22735.1 - 0.058 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.25 CAR22736.1 - 8.3e-71 238.4 0.0 1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22736.1 - 2.3e-38 132.0 0.1 4.3e-38 131.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22736.1 - 2.2e-07 30.5 0.0 3.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR22736.1 - 0.00049 19.0 0.0 0.00075 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CAR22736.1 - 0.0033 17.1 0.0 0.4 10.3 0.1 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAR22736.1 - 0.0064 16.4 0.0 0.027 14.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAR22736.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAR22736.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GrpE PF01025.19 CAR22737.1 - 2.8e-51 173.5 4.1 3.7e-51 173.1 4.1 1.1 1 0 0 1 1 1 1 GrpE DUF4578 PF15147.6 CAR22737.1 - 0.0043 17.9 0.6 0.0082 17.0 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4578) Pkinase PF00069.25 CAR22738.1 - 2.4e-64 217.2 0.0 4.3e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22738.1 - 7.5e-39 133.6 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22738.1 - 1.4e-07 31.2 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR22738.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAR22738.1 - 0.013 15.1 0.1 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CAR22738.1 - 0.055 12.4 0.5 0.13 11.1 0.5 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CAR22738.1 - 0.058 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L35Ae PF01247.18 CAR22739.1 - 8.2e-42 141.3 0.7 9.3e-42 141.1 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CAR22739.1 - 0.00058 20.0 0.0 1.4 9.2 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain POC3_POC4 PF10448.9 CAR22740.1 - 2.5e-08 34.0 0.0 2.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 PAC4 PF16093.5 CAR22740.1 - 0.00032 20.8 0.2 0.00046 20.3 0.2 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 AAA_24 PF13479.6 CAR22740.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain DUF2654 PF10849.8 CAR22740.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) DHFR_1 PF00186.19 CAR22741.1 - 1.7e-26 92.9 0.0 9.3e-25 87.2 0.0 2.4 1 1 0 1 1 1 1 Dihydrofolate reductase Oxysterol_BP PF01237.18 CAR22742.1 - 1.4e-62 211.7 6.4 2.3e-60 204.4 6.4 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.11 CAR22743.1 - 1.4e-100 337.5 53.5 1.6e-100 337.3 53.5 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ABC_membrane_2 PF06472.15 CAR22745.1 - 1.2e-85 287.2 7.5 1.8e-85 286.6 7.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CAR22745.1 - 1.9e-14 54.3 0.0 6.8e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CAR22745.1 - 0.00065 19.2 0.2 0.48 9.8 0.2 2.6 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR22745.1 - 0.0085 16.6 0.8 0.055 14.0 0.1 2.4 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 CAR22745.1 - 0.024 14.5 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR22745.1 - 0.081 12.7 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CAR22745.1 - 0.12 12.8 0.0 0.36 11.2 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR22745.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF1749 PF08538.10 CAR22746.1 - 3.4e-105 351.4 0.1 4.1e-105 351.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CAR22746.1 - 4.9e-06 26.0 0.0 0.0006 19.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CAR22746.1 - 9.1e-05 22.0 0.1 0.0011 18.5 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CAR22746.1 - 0.00074 19.2 0.1 0.078 12.6 0.0 2.4 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR22746.1 - 0.00099 19.8 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CAR22746.1 - 0.0042 16.7 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CAR22746.1 - 0.0096 15.7 0.0 1.5 8.6 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DUF900 PF05990.12 CAR22746.1 - 0.017 14.6 0.1 0.14 11.6 0.0 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Acetyltransf_1 PF00583.25 CAR22747.1 - 0.0058 16.9 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ACPS PF01648.20 CAR22748.1 - 4.3e-17 62.3 0.0 5.4e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.12 CAR22749.1 - 1.2e-48 165.7 0.2 1.5e-48 165.4 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.11 CAR22750.1 - 1.5e-19 69.9 0.0 1.5e-19 69.9 0.0 2.7 2 1 1 3 3 3 1 SGT1 protein Pkinase PF00069.25 CAR22751.1 - 2.8e-65 220.3 0.1 4.3e-65 219.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22751.1 - 2.4e-35 122.1 0.0 3.7e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22751.1 - 5.3e-08 32.5 0.0 1.2e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CAR22751.1 - 0.0009 18.3 0.1 0.0009 18.3 0.1 2.8 2 1 0 2 2 2 1 Haspin like kinase domain PBP1_TM PF14812.6 CAR22751.1 - 0.027 14.8 0.2 0.14 12.5 0.2 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3484 PF11983.8 CAR22751.1 - 0.11 13.7 0.9 0.4 11.8 0.9 2.0 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Mur_ligase_M PF08245.12 CAR22752.1 - 2.2e-07 31.1 0.0 0.00068 19.7 0.0 2.6 1 1 1 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 CAR22752.1 - 0.006 16.8 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain RRM_1 PF00076.22 CAR22753.1 - 0.00021 21.1 0.1 0.0057 16.5 0.1 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.18 CAR22754.1 - 6.7e-74 249.2 0.3 1.1e-68 232.0 0.0 3.2 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Trypan_glycop PF00913.19 CAR22754.1 - 0.35 10.1 3.8 0.67 9.1 3.8 1.4 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) WD40 PF00400.32 CAR22755.1 - 5e-40 134.7 16.8 6.7e-07 29.9 1.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR22755.1 - 1.2e-07 31.9 0.1 0.2 12.0 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CAR22755.1 - 3.9e-05 22.6 0.2 3.4 6.3 0.0 4.5 1 1 1 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 CAR22755.1 - 0.0022 16.7 1.9 3.5 6.2 0.0 3.9 3 1 0 4 4 4 2 Nucleoporin Nup120/160 Reg_prop PF07494.11 CAR22755.1 - 0.25 11.7 0.9 9.3 6.9 0.2 2.8 2 0 0 2 2 2 0 Two component regulator propeller MOZ_SAS PF01853.18 CAR22756.1 - 2.2e-82 275.1 0.1 3.5e-82 274.4 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 CAR22756.1 - 3.3e-22 78.1 0.0 7.2e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 CAR22756.1 - 6.4e-21 73.7 0.4 1.7e-20 72.4 0.4 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CAR22756.1 - 0.0015 18.9 0.0 0.0036 17.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR22756.1 - 0.0033 17.7 0.0 0.009 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family PTPA PF03095.15 CAR22757.1 - 5.4e-114 380.7 0.2 6.2e-114 380.5 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAGAT PF03982.13 CAR22758.1 - 7.2e-86 287.8 2.7 2.4e-74 249.9 0.0 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase LicD PF04991.13 CAR22759.1 - 1.2e-17 64.8 14.0 8.1e-14 52.3 3.5 3.0 2 1 1 3 3 3 2 LicD family Pkinase PF00069.25 CAR22760.1 - 5.9e-80 268.4 0.0 9.3e-80 267.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22760.1 - 7.4e-39 133.6 0.0 1.1e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CAR22760.1 - 2.3e-26 91.9 1.1 6.2e-15 55.3 0.1 3.1 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.6 CAR22760.1 - 8e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 CAR22760.1 - 6.1e-09 36.1 0.0 1.2e-06 28.7 0.0 2.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 CAR22760.1 - 9.2e-06 25.2 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR22760.1 - 0.00014 21.9 0.0 0.0082 16.1 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAR22760.1 - 0.00017 21.2 0.0 0.00032 20.3 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FHA_2 PF17913.1 CAR22760.1 - 0.014 15.7 0.3 6.1 7.2 0.0 3.2 3 0 0 3 3 3 0 FHA domain Haspin_kinase PF12330.8 CAR22760.1 - 0.086 11.8 0.0 0.2 10.6 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Asp PF00026.23 CAR22761.1 - 3e-107 358.7 0.0 3.8e-107 358.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR22761.1 - 3.4e-15 56.7 0.2 9.7e-13 48.7 0.2 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CAR22761.1 - 0.0013 18.6 0.0 0.004 16.9 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CAR22761.1 - 0.0027 18.3 0.0 0.61 10.8 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CAR22761.1 - 0.01 16.4 0.0 2.5 8.7 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Kinesin PF00225.23 CAR22762.1 - 1.6e-104 349.5 0.0 2.6e-104 348.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAR22762.1 - 2.2e-29 102.3 0.1 4.7e-29 101.2 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding Med9 PF07544.13 CAR22762.1 - 0.03 14.4 17.9 0.023 14.8 7.7 4.1 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA_33 PF13671.6 CAR22762.1 - 0.045 13.9 0.4 0.32 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain V_ATPase_I PF01496.19 CAR22762.1 - 1 7.2 4.7 1.8 6.4 4.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.6 CAR22762.1 - 1.1 8.9 21.6 0.13 11.9 10.3 3.0 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease TMPIT PF07851.13 CAR22762.1 - 2.3 7.4 7.9 13 4.9 3.7 2.2 2 0 0 2 2 2 0 TMPIT-like protein HAUS-augmin3 PF14932.6 CAR22762.1 - 2.5 7.6 15.1 2.4 7.7 13.6 1.7 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 MPS2 PF17060.5 CAR22762.1 - 3.3 6.9 8.2 4.1 6.6 0.1 2.6 3 0 0 3 3 3 0 Monopolar spindle protein 2 AAA_13 PF13166.6 CAR22762.1 - 3.7 6.1 6.6 0.62 8.6 2.8 1.6 2 0 0 2 2 2 0 AAA domain FapA PF03961.13 CAR22762.1 - 3.9 6.0 9.2 0.9 8.1 5.2 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A XLF PF09302.11 CAR22762.1 - 4.8 7.3 8.7 92 3.1 8.7 2.5 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Peripla_BP_2 PF01497.18 CAR22763.1 - 0.0069 16.0 0.1 0.13 11.8 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein NTP_transf_4 PF13562.6 CAR22763.1 - 0.023 14.9 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Sugar nucleotidyl transferase Methyltransf_15 PF09445.10 CAR22764.1 - 4.5e-60 202.0 0.0 6e-60 201.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CAR22764.1 - 8.5e-07 29.6 0.0 1.5e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR22764.1 - 7.5e-06 25.8 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CAR22764.1 - 2.4e-05 24.1 0.0 4.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.20 CAR22764.1 - 0.0032 16.8 0.0 0.007 15.7 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CAR22764.1 - 0.0033 18.0 0.0 0.0074 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAR22764.1 - 0.0054 16.3 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CAR22764.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CAR22764.1 - 0.0092 15.6 0.0 0.026 14.2 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical protein 95 tRNA_U5-meth_tr PF05958.11 CAR22764.1 - 0.021 13.8 0.0 0.041 12.9 0.0 1.3 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase N6_Mtase PF02384.16 CAR22764.1 - 0.045 13.0 0.0 0.098 11.9 0.0 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 CAR22764.1 - 0.084 12.6 0.0 0.25 11.0 0.0 1.8 1 1 1 2 2 2 0 DNA methylase Abhydrolase_1 PF00561.20 CAR22766.1 - 1.9e-14 53.9 0.0 1.8e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR22766.1 - 6e-10 38.8 0.0 2.9e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR22766.1 - 4.2e-06 27.5 0.0 7.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CAR22766.1 - 0.072 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) GA-like PF17573.2 CAR22766.1 - 0.24 11.4 0.0 0.47 10.4 0.0 1.4 1 0 0 1 1 1 0 GA-like domain Pet20 PF08692.10 CAR22767.1 - 3.3e-16 60.2 0.5 1.2e-06 29.3 0.0 3.3 2 1 1 3 3 3 2 Mitochondrial protein Pet20 tRNA-synt_1 PF00133.22 CAR22769.1 - 3e-42 144.7 0.0 9.2e-34 116.6 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CAR22769.1 - 9.4e-16 57.5 1.1 1.3e-08 34.0 0.0 3.8 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CAR22769.1 - 1.4e-12 47.8 0.1 6.2e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CAR22769.1 - 3.8e-07 29.7 0.0 9.3e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain adh_short PF00106.25 CAR22770.1 - 2.3e-24 85.9 0.1 2.8e-20 72.6 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAR22770.1 - 1.1e-11 44.7 0.0 5e-10 39.3 0.0 2.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR22770.1 - 0.00088 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CAR22770.1 - 0.0023 17.3 0.2 0.0084 15.5 0.2 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CAR22770.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR22770.1 - 0.05 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase STN1_2 PF09170.10 CAR22771.1 - 0.12 12.6 0.7 3.5 7.8 0.1 3.1 3 1 1 4 4 4 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 STIMATE PF12400.8 CAR22772.1 - 4.3e-44 150.1 2.3 4.3e-44 150.1 2.3 1.8 2 0 0 2 2 2 1 STIMATE family DUF2208 PF09973.9 CAR22772.1 - 0.49 10.0 2.5 0.75 9.4 2.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF1258 PF06869.12 CAR22773.1 - 0.021 14.3 1.0 0.03 13.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) S_layer_N PF05123.12 CAR22773.1 - 1.7 8.4 8.2 0.064 13.1 2.7 1.5 2 0 0 2 2 2 0 S-layer like family, N-terminal region MutL_C PF08676.11 CAR22774.1 - 7.2e-13 48.5 0.1 1.8e-11 44.0 0.1 2.3 1 1 1 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 CAR22774.1 - 3.2e-07 30.3 0.0 5.7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAR22774.1 - 5.2e-05 23.7 0.1 0.00011 22.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ANAPC5 PF12862.7 CAR22775.1 - 1e-27 96.0 2.4 2.4e-27 94.8 2.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 CAR22775.1 - 0.0039 17.1 0.2 0.078 13.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR22775.1 - 0.024 14.9 0.1 0.21 11.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR22775.1 - 0.038 14.2 1.4 0.11 12.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR22775.1 - 0.057 14.3 0.1 1.6 9.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAR22775.1 - 0.16 11.9 0.1 0.49 10.3 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CLP1_P PF16575.5 CAR22776.1 - 3.5e-32 111.7 0.0 5.4e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CAR22776.1 - 6.8e-27 93.5 0.0 1.5e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CAR22776.1 - 1.1e-23 83.9 0.1 2.2e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 AAA_16 PF13191.6 CAR22776.1 - 0.0046 17.3 0.0 0.0092 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CAR22776.1 - 0.0088 16.3 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CAR22776.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CAR22776.1 - 0.023 15.2 0.0 0.054 14.0 0.0 1.6 2 0 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 CAR22776.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 CAR22776.1 - 0.07 12.4 0.1 0.65 9.2 0.0 2.2 2 1 0 2 2 2 0 Septin Sigma54_activat PF00158.26 CAR22776.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CAR22776.1 - 0.083 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAR22776.1 - 0.12 12.9 0.1 0.8 10.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain Rhodanese PF00581.20 CAR22777.1 - 1e-17 64.6 0.0 1.1e-08 35.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain SET PF00856.28 CAR22778.1 - 6.7e-11 42.9 1.0 3.8e-10 40.4 1.0 2.0 1 1 0 1 1 1 1 SET domain IRF-2BP1_2 PF11261.8 CAR22778.1 - 0.055 13.0 0.2 0.055 13.0 0.2 1.9 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger PAN_3 PF08277.12 CAR22778.1 - 0.081 12.7 2.2 0.42 10.5 0.8 2.5 2 0 0 2 2 2 0 PAN-like domain Atg29_N PF18388.1 CAR22779.1 - 7e-16 57.8 0.3 1.1e-15 57.2 0.3 1.3 1 0 0 1 1 1 1 Atg29 N-terminal domain Phage_TAC_13 PF16459.5 CAR22779.1 - 0.11 13.0 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC DNA_pol_B PF00136.21 CAR22780.1 - 2.4e-107 359.5 0.7 5.2e-107 358.4 0.7 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CAR22780.1 - 8.1e-17 61.4 1.7 1.6e-08 34.1 0.0 2.9 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CAR22780.1 - 5.4e-11 42.8 13.2 1.3e-10 41.5 13.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF1744 PF08490.12 CAR22780.1 - 0.047 12.2 0.0 0.095 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Tma16 PF11176.8 CAR22781.1 - 4.5e-48 162.8 2.9 5.7e-48 162.5 2.9 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Acetyltransf_1 PF00583.25 CAR22783.1 - 1.5e-14 54.2 0.2 1.7e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR22783.1 - 8e-12 45.2 0.9 1e-11 44.9 0.9 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR22783.1 - 1.6e-11 44.5 1.4 2.2e-11 44.0 1.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR22783.1 - 5.9e-06 26.2 0.2 9.2e-06 25.5 0.2 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CAR22783.1 - 2.4e-05 24.5 0.4 2.8e-05 24.3 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR22783.1 - 0.0035 17.4 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CAR22783.1 - 0.0039 16.9 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CAR22783.1 - 0.072 13.2 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DnaJ PF00226.31 CAR22784.1 - 8.7e-15 54.6 0.7 3.2e-14 52.8 0.7 2.0 1 0 0 1 1 1 1 DnaJ domain RRM_9 PF18444.1 CAR22785.1 - 4.2e-32 109.8 1.0 8.1e-32 108.9 1.0 1.5 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 CAR22785.1 - 8.2e-14 51.0 0.0 2.6e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 CAR22785.1 - 3.9e-07 29.7 3.2 8.9e-07 28.6 3.2 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAR22785.1 - 6.9e-06 26.3 15.9 8.5e-05 22.9 1.1 3.3 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR22785.1 - 0.048 13.4 4.4 0.23 11.3 4.4 2.3 1 0 0 1 1 1 0 Leucine rich repeat NTF2 PF02136.20 CAR22785.1 - 0.057 14.0 1.3 1.9 9.1 1.2 2.7 1 1 1 2 2 2 0 Nuclear transport factor 2 (NTF2) domain Rad17 PF03215.15 CAR22786.1 - 0.019 14.9 0.3 0.082 12.8 0.0 1.9 1 1 0 2 2 2 0 Rad17 P-loop domain Cyt-b5 PF00173.28 CAR22787.1 - 5.5e-14 52.1 0.0 7.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFR_dimer PF04253.15 CAR22788.1 - 9.5e-28 96.7 0.1 2e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CAR22788.1 - 0.0017 18.0 0.0 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PIGA PF08288.12 CAR22789.1 - 4.8e-40 136.0 2.1 4.8e-40 136.0 2.1 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 CAR22789.1 - 5.7e-26 91.1 0.0 9e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR22789.1 - 4.3e-25 88.7 0.5 9.3e-25 87.6 0.4 1.6 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CAR22789.1 - 3.5e-21 76.0 0.0 6.6e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CAR22789.1 - 3e-09 37.5 0.0 5.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CAR22789.1 - 0.00011 22.3 0.3 0.00024 21.1 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CAR22789.1 - 0.089 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Asparaginase_C PF17763.1 CAR22789.1 - 0.16 12.2 0.2 0.79 10.0 0.1 2.2 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain CAP_GLY PF01302.25 CAR22790.1 - 7e-20 70.8 0.7 1.2e-19 70.1 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain MscS_porin PF12795.7 CAR22790.1 - 0.00037 20.1 20.2 0.00037 20.1 20.2 3.4 2 2 0 3 3 3 1 Mechanosensitive ion channel porin domain GAS PF13851.6 CAR22790.1 - 0.0057 16.0 5.2 0.0057 16.0 5.2 4.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CAR22790.1 - 0.012 15.6 9.0 0.012 15.6 9.0 5.8 5 1 2 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CAR22790.1 - 0.078 13.2 42.4 0.93 9.7 5.5 5.2 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) Lip_prot_lig_C PF10437.9 CAR22790.1 - 0.24 11.4 2.5 13 5.9 0.2 3.6 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus KIP1 PF07765.12 CAR22790.1 - 0.25 11.5 6.3 0.54 10.4 2.6 3.5 2 1 1 3 3 3 0 KIP1-like protein Cnn_1N PF07989.11 CAR22790.1 - 3.1 8.0 38.9 0.39 10.9 1.5 5.7 3 1 2 5 5 5 0 Centrosomin N-terminal motif 1 Spc7 PF08317.11 CAR22790.1 - 7.2 5.4 50.2 0.39 9.6 15.3 3.5 2 1 1 3 3 3 0 Spc7 kinetochore protein Sec20 PF03908.13 CAR22790.1 - 8.6 6.4 8.2 7.5 6.5 2.4 3.2 2 0 0 2 2 2 0 Sec20 EF-hand_7 PF13499.6 CAR22791.1 - 1.4e-25 89.5 13.3 1.5e-14 54.2 2.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAR22791.1 - 1e-24 84.1 16.0 2.8e-07 29.6 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CAR22791.1 - 3.3e-20 70.2 13.5 5.2e-06 26.0 0.4 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CAR22791.1 - 6.8e-19 67.5 15.1 1.2e-10 41.1 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CAR22791.1 - 8.3e-11 40.9 14.8 9e-05 21.8 0.2 4.2 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 CAR22791.1 - 9.9e-07 29.0 0.3 0.057 13.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CAR22791.1 - 2.4e-06 27.4 1.9 0.0095 15.9 0.1 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAR22791.1 - 0.00036 20.8 0.6 0.52 10.6 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CAR22791.1 - 0.012 15.5 1.0 2.4 8.1 0.1 3.5 1 1 3 4 4 4 0 Caleosin related protein Dockerin_1 PF00404.18 CAR22791.1 - 0.034 14.4 0.3 7.1 6.9 0.4 2.4 2 0 0 2 2 2 0 Dockerin type I domain SUB1_ProdP9 PF18213.1 CAR22791.1 - 0.038 13.8 0.3 0.13 12.1 0.2 2.0 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 PhetRS_B1 PF18262.1 CAR22791.1 - 0.072 13.3 2.7 0.11 12.7 0.6 2.3 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain MgtE_N PF03448.17 CAR22791.1 - 0.088 13.4 0.7 0.088 13.4 0.7 2.5 2 1 0 2 2 2 0 MgtE intracellular N domain EF-hand_14 PF17959.1 CAR22791.1 - 0.2 12.0 1.4 0.63 10.4 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain VCBS PF13517.6 CAR22791.1 - 1.2 9.8 4.6 2.6 8.7 0.0 2.6 3 1 0 3 3 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DcpS_C PF11969.8 CAR22793.1 - 1.6e-16 60.8 1.2 9.3e-16 58.3 1.2 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 CAR22793.1 - 1.5e-15 57.4 2.4 7.1e-15 55.2 2.9 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 CAR22793.1 - 7.1e-15 55.5 0.0 2e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 HIT domain zf-BED PF02892.15 CAR22793.1 - 0.017 15.2 0.7 0.038 14.0 0.7 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 CAR22793.1 - 0.94 10.5 5.3 0.49 11.4 2.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger AAA PF00004.29 CAR22794.1 - 1.5e-42 145.1 0.0 2.7e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR22794.1 - 5.6e-09 35.7 0.2 1.2e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CAR22794.1 - 1e-07 31.8 0.5 1e-07 31.8 0.5 1.6 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CAR22794.1 - 2.7e-07 31.1 0.0 8.9e-05 22.9 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CAR22794.1 - 1.3e-06 28.5 0.2 3.8e-05 23.7 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR22794.1 - 1.2e-05 25.4 0.0 3.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CAR22794.1 - 3.2e-05 23.7 0.0 7.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CAR22794.1 - 0.00018 21.5 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CAR22794.1 - 0.0019 18.6 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 CAR22794.1 - 0.0019 18.5 0.2 0.031 14.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 CAR22794.1 - 0.0026 17.0 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CAR22794.1 - 0.0063 16.7 0.0 0.022 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAR22794.1 - 0.0064 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CAR22794.1 - 0.0073 16.9 0.0 0.028 14.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 CAR22794.1 - 0.012 15.4 0.8 0.036 13.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CAR22794.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Prot_ATP_OB_N PF17758.1 CAR22794.1 - 0.018 14.6 0.3 0.059 13.0 0.1 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 CAR22794.1 - 0.023 14.9 0.2 0.067 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CAR22794.1 - 0.035 14.1 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CAR22794.1 - 0.037 13.4 1.6 0.11 11.9 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 CAR22794.1 - 0.044 13.6 3.9 0.96 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAR22794.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CAR22794.1 - 0.06 12.9 0.1 0.19 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CAR22794.1 - 0.066 12.7 1.3 0.12 11.8 0.2 1.9 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 CAR22794.1 - 0.076 12.1 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Phage_GP20 PF06810.11 CAR22794.1 - 0.1 12.4 3.5 0.91 9.3 3.0 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA_3 PF07726.11 CAR22794.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CAR22794.1 - 0.13 12.1 0.1 0.52 10.2 0.0 2.0 1 1 0 1 1 1 0 NACHT domain HAUS6_N PF14661.6 CAR22794.1 - 0.31 10.6 2.6 0.49 9.9 2.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AAA_23 PF13476.6 CAR22794.1 - 0.5 10.8 5.9 12 6.3 2.6 2.5 2 1 0 2 2 2 0 AAA domain OmpH PF03938.14 CAR22794.1 - 0.55 10.6 7.0 0.4 11.0 3.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Hexapep PF00132.24 CAR22795.1 - 1.5e-06 27.7 10.7 0.0011 18.6 1.0 4.1 2 1 3 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CAR22795.1 - 3.3e-05 23.0 2.7 0.00023 20.2 2.0 2.2 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 CAR22795.1 - 0.00019 21.8 0.0 0.00035 21.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CAR22795.1 - 0.00044 19.9 9.0 0.13 12.1 6.9 3.4 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 CAR22795.1 - 0.0018 17.9 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 CAR22795.1 - 0.3 9.2 7.1 0.13 10.4 3.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4954) UbiA PF01040.18 CAR22796.1 - 7.8e-47 159.7 11.8 7.8e-47 159.7 11.8 1.5 2 0 0 2 2 2 1 UbiA prenyltransferase family FA_desaturase PF00487.24 CAR22796.1 - 0.0018 18.2 3.3 0.0018 18.2 3.3 2.3 2 0 0 2 2 2 2 Fatty acid desaturase MitMem_reg PF13012.6 CAR22797.1 - 3.1e-32 111.3 0.3 5.8e-32 110.4 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CAR22797.1 - 3.5e-30 104.4 0.0 6.6e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ATP_bind_1 PF03029.17 CAR22798.1 - 4.2e-79 265.7 0.1 5.4e-79 265.4 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CAR22798.1 - 0.027 14.8 0.0 0.063 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAR22798.1 - 0.037 14.2 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAR22798.1 - 0.068 13.7 0.1 0.71 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CAR22798.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TBCA PF02970.16 CAR22800.1 - 2.5e-25 88.6 4.9 2.9e-25 88.4 4.2 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A Fzo_mitofusin PF04799.13 CAR22800.1 - 0.0033 17.0 1.2 0.005 16.4 1.2 1.4 1 0 0 1 1 1 1 fzo-like conserved region Pkinase PF00069.25 CAR22802.1 - 4.5e-45 154.1 0.0 9.2e-42 143.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22802.1 - 1.3e-18 67.3 0.0 3.9e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR22802.1 - 0.036 13.4 0.0 0.059 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CAR22802.1 - 0.17 11.7 0.5 0.6 10.0 0.0 2.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pneumo_att_G PF05539.11 CAR22802.1 - 5.2 6.6 11.4 9.7 5.7 11.4 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G WD40 PF00400.32 CAR22803.1 - 3e-23 81.7 24.6 3.5e-05 24.5 1.0 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.8 CAR22803.1 - 0.00024 19.9 1.8 1.2 7.7 0.2 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 DivIC PF04977.15 CAR22803.1 - 0.018 14.8 0.3 0.034 13.9 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator TSC22 PF01166.18 CAR22803.1 - 0.021 15.1 0.5 0.041 14.2 0.5 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 CAR22803.1 - 0.037 14.1 0.1 0.063 13.4 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor Shugoshin_N PF07558.11 CAR22803.1 - 0.39 10.6 5.0 0.67 9.9 5.0 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 CAR22803.1 - 0.44 10.7 3.6 0.75 9.9 3.6 1.3 1 0 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.19 CAR22804.1 - 0 1013.5 0.7 0 1013.2 0.7 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Rootletin PF15035.6 CAR22804.1 - 0.023 14.7 1.1 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Sec3_C_2 PF15278.6 CAR22804.1 - 0.088 13.2 0.7 0.58 10.5 0.3 2.6 1 1 1 2 2 2 0 Sec3 exocyst complex subunit GHMP_kinases_N PF00288.26 CAR22805.1 - 4.6e-19 68.4 0.4 1.4e-18 66.8 0.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAR22805.1 - 1.4e-05 25.4 0.1 0.00013 22.3 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal Mtc PF03820.17 CAR22806.1 - 2e-123 411.4 0.0 2.2e-123 411.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NLE PF08154.12 CAR22807.1 - 4e-22 78.5 0.1 8.6e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 CAR22807.1 - 1e-21 76.8 10.3 3.7e-06 27.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 CAR22807.1 - 2.7e-09 36.2 2.9 0.00087 18.1 0.1 2.7 2 1 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CAR22807.1 - 0.0068 16.7 0.2 0.39 11.0 0.0 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain N2227 PF07942.12 CAR22808.1 - 7.3e-62 209.0 0.0 1e-61 208.6 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein MFS_1 PF07690.16 CAR22809.1 - 1.4e-27 96.6 35.9 1.4e-27 96.6 35.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Tubulin_3 PF14881.6 CAR22810.1 - 5e-21 75.2 0.0 9.5e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CAR22810.1 - 9.6e-16 58.2 0.2 2.6e-15 56.8 0.2 1.7 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CAR22810.1 - 0.0031 17.7 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain IPPT PF01715.17 CAR22811.1 - 1.3e-66 224.7 0.1 1.9e-66 224.1 0.1 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 CAR22811.1 - 4.1e-06 26.4 0.1 6.9e-05 22.4 0.0 2.6 3 0 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 CAR22811.1 - 9.7e-05 22.6 0.0 0.0017 18.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR22811.1 - 0.0011 19.5 1.2 0.0067 17.0 0.0 2.7 2 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CAR22811.1 - 0.0019 17.5 0.0 0.0072 15.6 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 CAR22811.1 - 0.0049 16.3 0.0 0.74 9.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_25 PF13481.6 CAR22811.1 - 0.0094 15.5 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR22811.1 - 0.022 15.2 0.1 0.28 11.6 0.0 2.6 3 0 0 3 3 3 0 RNA helicase dNK PF01712.19 CAR22811.1 - 0.022 14.6 0.8 6.2 6.6 0.1 2.8 2 1 0 2 2 2 0 Deoxynucleoside kinase RsgA_GTPase PF03193.16 CAR22811.1 - 0.026 14.5 0.2 0.081 12.8 0.2 1.8 1 1 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CAR22811.1 - 0.051 13.8 0.0 9.8 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 CAR22811.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PhoH PF02562.16 CAR22811.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein BRO1 PF03097.18 CAR22812.1 - 8e-96 321.2 3.0 1.1e-95 320.7 3.0 1.2 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CAR22812.1 - 1.6e-29 103.1 9.3 2.1e-27 96.2 9.4 2.6 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV Myb_DNA-binding PF00249.31 CAR22814.1 - 1.2e-25 89.4 1.8 1.2e-11 44.6 0.5 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR22814.1 - 9e-21 73.9 3.4 2.2e-12 47.0 1.7 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CAR22814.1 - 7.7e-07 28.9 2.6 7.7e-07 28.9 2.6 2.4 3 1 0 3 3 3 1 pre-mRNA splicing factor component Rap1_C PF11626.8 CAR22814.1 - 0.00054 20.0 0.3 0.0027 17.7 0.0 2.3 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MLTR_LBD PF17765.1 CAR22814.1 - 0.067 13.3 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Myb_DNA-bind_4 PF13837.6 CAR22814.1 - 2.6 8.5 9.5 4.1 7.9 0.5 3.9 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain CAF20 PF17052.5 CAR22815.1 - 1.2e-46 158.8 2.4 1.5e-46 158.4 2.4 1.1 1 0 0 1 1 1 1 Cap associated factor DnaJ PF00226.31 CAR22816.1 - 5.2e-28 96.9 2.2 8.8e-28 96.2 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CAR22816.1 - 4.7e-21 75.4 0.1 6.2e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CAR22816.1 - 2.6e-14 53.3 21.2 4e-14 52.7 21.2 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAR22816.1 - 2.1e-05 24.4 7.0 0.0015 18.4 0.4 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 CAR22816.1 - 0.19 11.4 9.7 0.23 11.1 2.2 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 CAR22816.1 - 0.34 10.9 11.7 1.3 9.0 1.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 CAR22816.1 - 6.4 7.0 7.6 0.55 10.4 1.5 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 CAR22816.1 - 8.5 6.4 12.2 48 4.0 12.2 2.0 1 1 0 1 1 1 0 zinc-ribbons Pkinase PF00069.25 CAR22817.1 - 2.2e-44 151.8 0.3 4e-22 78.8 0.4 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR22817.1 - 9e-12 44.8 1.5 6.7e-08 32.1 0.4 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase RRM_1 PF00076.22 CAR22818.1 - 4.6e-11 42.4 0.0 7.8e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR22818.1 - 6.8e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif GMP_synt_C PF00958.22 CAR22820.1 - 5e-45 151.5 0.0 8.9e-45 150.7 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CAR22820.1 - 9e-42 143.0 0.0 1.5e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CAR22820.1 - 1.9e-07 30.5 0.0 4.6e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CAR22820.1 - 6.6e-07 29.3 0.0 3.4e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CAR22820.1 - 0.0088 14.9 0.1 0.018 13.8 0.0 1.5 2 0 0 2 2 2 1 tRNA methyl transferase Arginosuc_synth PF00764.19 CAR22820.1 - 0.012 15.0 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 CAR22820.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 CAR22820.1 - 0.012 15.1 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 CAR22820.1 - 0.049 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) HEM4 PF02602.15 CAR22821.1 - 4.8e-44 150.4 0.0 5.4e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TRAPPC10 PF12584.8 CAR22822.1 - 8.9e-10 38.5 0.0 2.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 CAR22822.1 - 0.0066 16.1 0.2 0.013 15.1 0.2 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_3 PF07720.12 CAR22822.1 - 0.045 13.8 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 CAR22824.1 - 1.8e-16 60.1 0.3 3.7e-16 59.1 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAR22824.1 - 0.0012 19.2 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4570 PF15134.6 CAR22825.1 - 0.094 12.7 1.4 2.7 8.0 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) LAGLIDADG_3 PF14528.6 CAR22825.1 - 0.1 12.9 0.4 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 LAGLIDADG-like domain TERB2 PF15101.6 CAR22825.1 - 0.93 9.5 3.8 1.9 8.5 3.8 1.7 1 1 0 1 1 1 0 Telomere-associated protein TERB2 MFS_1 PF07690.16 CAR22826.1 - 1.6e-05 24.0 26.4 1.6e-05 24.0 26.4 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily FSH1 PF03959.13 CAR22827.1 - 3.9e-67 226.0 0.0 4.5e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CAR22827.1 - 0.00013 21.8 0.1 0.00052 19.9 0.1 1.9 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 CAR22827.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) UCH PF00443.29 CAR22828.1 - 4.2e-52 177.2 3.0 5.1e-52 176.9 3.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR22828.1 - 2.8e-13 50.2 8.2 2.8e-13 50.2 8.2 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CAR22828.1 - 2.2e-10 40.7 9.6 2.2e-10 40.7 9.6 2.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RanBP PF00641.18 CAR22828.1 - 9.3 5.7 17.7 4.8 6.6 4.1 4.4 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others Phosducin PF02114.16 CAR22829.1 - 2.1e-15 56.4 0.8 2.6e-15 56.1 0.8 1.1 1 0 0 1 1 1 1 Phosducin dsDNA_bind PF01984.20 CAR22829.1 - 0.044 14.1 0.1 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Mre11_DNA_bind PF04152.14 CAR22830.1 - 5.7e-45 153.7 0.2 5.7e-45 153.7 0.2 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CAR22830.1 - 3.2e-13 50.6 1.0 5.6e-13 49.9 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CAR22830.1 - 0.00046 20.4 0.0 0.018 15.2 0.0 3.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain His_Phos_1 PF00300.22 CAR22831.1 - 3.6e-45 154.0 0.0 4.5e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.20 CAR22832.1 - 9.6e-15 55.0 0.0 1.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CAR22833.1 - 6.3e-13 49.2 0.0 7.5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain RRP36 PF06102.12 CAR22834.1 - 1.2e-36 126.2 32.1 1.2e-36 126.2 32.1 2.2 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Piezo_RRas_bdg PF12166.8 CAR22834.1 - 0.079 12.2 3.7 0.12 11.6 3.7 1.4 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain MRP_L53 PF10780.9 CAR22835.1 - 1.5e-19 69.9 0.1 2.3e-19 69.3 0.1 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Thioredoxin PF00085.20 CAR22836.1 - 3.1e-23 81.7 0.1 7e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAR22836.1 - 0.00013 22.4 0.3 0.00079 19.8 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CAR22836.1 - 0.0012 18.3 0.2 0.0021 17.5 0.0 1.4 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 CAR22836.1 - 0.0019 18.0 0.1 0.0039 17.0 0.1 1.4 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 CAR22836.1 - 0.0054 17.0 0.2 3.1 8.2 0.0 3.1 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CAR22836.1 - 0.041 14.1 0.2 0.26 11.5 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin-like Glutaredoxin PF00462.24 CAR22836.1 - 0.043 14.0 0.1 0.094 13.0 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin DSBA PF01323.20 CAR22836.1 - 0.07 12.9 0.2 0.31 10.8 0.0 2.1 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 CAR22836.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 CAR22836.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AMMECR1 PF01871.17 CAR22837.1 - 3.4e-37 127.6 0.0 4.2e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.25 CAR22838.1 - 2.1e-52 177.4 0.1 2.8e-52 177.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR22838.1 - 7.7e-35 120.5 0.1 9.4e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR22838.1 - 1.4e-11 44.6 0.0 1.9e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CAR22838.1 - 4.6e-06 26.2 0.0 1.6e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 CAR22838.1 - 6.6e-05 22.2 0.1 9.9e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 CAR22838.1 - 9e-05 22.0 0.3 0.00049 19.6 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CAR22838.1 - 0.024 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UPF0158 PF03682.13 CAR22838.1 - 0.087 12.8 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) NAD_binding_10 PF13460.6 CAR22838.1 - 0.13 12.1 0.3 0.25 11.2 0.3 1.7 1 1 0 1 1 1 0 NAD(P)H-binding DUF2564 PF10819.8 CAR22838.1 - 0.16 12.4 0.1 2.5 8.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) SNF2_N PF00176.23 CAR22839.1 - 4.2e-72 242.8 0.6 1.1e-71 241.4 0.6 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR22839.1 - 1.9e-21 76.4 1.9 2.1e-19 69.9 0.0 3.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CAR22839.1 - 1.8e-14 53.5 1.3 6.1e-14 51.9 0.1 2.6 3 0 0 3 3 3 1 Bromodomain SnAC PF14619.6 CAR22839.1 - 1.2e-11 45.0 1.3 1.2e-11 45.0 1.3 4.3 3 2 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 CAR22839.1 - 9.8e-07 29.0 6.4 9.8e-07 29.0 6.4 4.5 5 0 0 5 5 5 1 HSA DUF695 PF05117.12 CAR22839.1 - 0.031 14.4 1.6 0.13 12.5 0.9 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF695) TAFII55_N PF04658.13 CAR22841.1 - 1.3e-50 171.3 0.0 1.3e-50 171.3 0.0 2.3 2 1 0 2 2 2 1 TAFII55 protein conserved region RrnaAD PF00398.20 CAR22842.1 - 6.7e-56 189.3 0.0 7.7e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.12 CAR22842.1 - 0.024 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) S1 PF00575.23 CAR22844.1 - 4.9e-45 151.8 30.6 2.2e-10 40.7 1.2 12.4 12 0 0 12 12 12 7 S1 RNA binding domain TPR_19 PF14559.6 CAR22844.1 - 5.2e-09 36.5 0.1 0.0097 16.4 0.0 3.3 3 1 0 3 3 2 2 Tetratricopeptide repeat Suf PF05843.14 CAR22844.1 - 3.1e-06 27.4 10.9 1.4e-05 25.2 1.1 3.4 1 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CAR22844.1 - 5.3e-06 26.8 1.6 1.4 10.0 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAR22844.1 - 0.0039 17.8 0.0 6.8 7.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CAR22844.1 - 0.015 15.3 0.7 0.081 12.9 0.1 2.2 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Pfg27 PF09216.10 CAR22844.1 - 0.028 14.3 0.1 23 4.8 0.0 3.6 3 1 0 3 3 3 0 Pfg27 TPR_15 PF13429.6 CAR22844.1 - 0.032 13.5 2.3 2.3 7.4 0.1 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CAR22844.1 - 0.037 14.6 1.4 14 6.6 0.2 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR22844.1 - 0.061 13.5 0.1 16 5.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2025 PF09634.10 CAR22844.1 - 0.089 12.8 0.1 0.68 10.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2025) TPR_12 PF13424.6 CAR22844.1 - 0.2 11.9 0.1 24 5.3 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat tRNA_anti-codon PF01336.25 CAR22844.1 - 0.42 10.6 2.0 12 6.0 0.0 4.0 4 0 0 4 4 4 0 OB-fold nucleic acid binding domain RNA_pol_Rbc25 PF08292.12 CAR22844.1 - 1.7 8.9 7.5 1.2 9.4 0.0 4.2 5 0 0 5 5 3 0 RNA polymerase III subunit Rpc25 SDA1 PF05285.12 CAR22844.1 - 2.4 7.5 27.3 4.6 6.6 2.9 2.4 2 0 0 2 2 2 0 SDA1 P5-ATPase PF12409.8 CAR22845.1 - 2.2e-33 115.0 2.7 3.1e-33 114.6 0.1 2.5 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 CAR22845.1 - 1.3e-29 103.0 0.0 2.9e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CAR22845.1 - 2.8e-12 47.4 0.0 3.7e-05 24.1 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAR22845.1 - 3.4e-06 26.6 0.0 7.7e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CAR22845.1 - 1.9e-05 24.6 0.0 4.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 CAR22845.1 - 3e-05 23.8 7.5 8.1e-05 22.4 7.5 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 CAR22845.1 - 0.15 11.8 0.1 6.6 6.4 0.0 2.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SCAMP PF04144.13 CAR22845.1 - 1.7 8.9 12.2 3.6 7.8 2.3 2.8 2 1 1 3 3 3 0 SCAMP family Mpv17_PMP22 PF04117.12 CAR22846.1 - 5.3e-18 65.0 0.3 1.8e-17 63.3 0.3 2.0 1 0 0 1 1 1 1 Mpv17 / PMP22 family S10_plectin PF03501.15 CAR22847.1 - 3.6e-43 145.6 0.3 4.1e-43 145.4 0.3 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 CAR22847.1 - 0.035 13.9 0.1 0.046 13.5 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_45 PF14947.6 CAR22847.1 - 0.06 13.3 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix EF-hand_7 PF13499.6 CAR22848.1 - 4.4e-13 49.5 0.9 5.7e-08 33.1 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR22848.1 - 1.7e-08 33.7 1.0 0.067 13.2 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CAR22848.1 - 4.1e-06 26.0 0.0 7 6.5 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CAR22848.1 - 0.0025 17.6 0.0 0.89 9.5 0.0 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CAR22848.1 - 0.0078 15.7 0.1 6.2 6.5 0.0 3.9 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 CAR22848.1 - 0.038 14.3 0.2 14 6.1 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain Suppressor_P21 PF11479.8 CAR22848.1 - 0.13 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain PIN_4 PF13638.6 CAR22849.1 - 0.00032 21.0 0.0 0.005 17.1 0.0 2.5 1 1 1 2 2 2 1 PIN domain FA_hydroxylase PF04116.13 CAR22850.1 - 7.6e-27 94.3 20.2 7.6e-27 94.3 20.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase_5 PF13507.6 CAR22851.1 - 9.3e-102 339.6 0.1 1.6e-101 338.8 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CAR22851.1 - 8.2e-43 146.2 0.1 4.7e-30 104.8 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CAR22851.1 - 1.9e-28 98.8 0.0 3.4e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CAR22851.1 - 3.4e-22 78.7 0.0 9.8e-22 77.2 0.0 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF2462 PF09495.10 CAR22852.1 - 1.6e-14 54.4 12.4 2e-14 54.1 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.20 CAR22853.1 - 4.2e-08 33.3 1.6 7.7e-07 29.2 0.4 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein Spt4 PF06093.13 CAR22854.1 - 1.3e-28 98.9 0.4 1.5e-28 98.7 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.6 CAR22854.1 - 0.094 12.1 1.1 0.17 11.2 1.1 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger TackOD1 PF18551.1 CAR22854.1 - 0.21 11.3 1.4 0.28 10.8 1.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 Glutaredoxin PF00462.24 CAR22855.1 - 3e-07 30.5 0.0 7.6e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 CAR22855.1 - 0.00043 20.1 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 CAR22855.1 - 0.028 14.4 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DUF953 PF06110.11 CAR22855.1 - 0.057 13.0 0.6 0.076 12.6 0.5 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) MFS_1 PF07690.16 CAR22856.1 - 5.6e-22 78.2 20.3 5.6e-22 78.2 20.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_S8 PF00410.19 CAR22857.1 - 1e-23 83.7 0.2 1.6e-23 83.0 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Arrestin_C PF02752.22 CAR22858.1 - 7.7e-23 81.4 1.3 1.8e-22 80.2 0.2 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CAR22858.1 - 7e-05 22.9 0.2 0.026 14.6 0.1 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain F-box PF00646.33 CAR22859.1 - 1.6e-08 34.2 2.3 1.8e-08 34.0 0.3 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CAR22859.1 - 1.1e-06 28.4 0.4 9.3e-06 25.4 0.3 2.5 2 0 0 2 2 2 1 F-box-like HSP70 PF00012.20 CAR22860.1 - 3.7e-215 715.7 11.3 4.2e-215 715.5 11.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR22860.1 - 3.6e-19 68.7 1.4 1.6e-15 56.8 0.3 2.7 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CAR22860.1 - 0.00085 19.1 0.0 0.002 17.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain P21-Arc PF04062.14 CAR22861.1 - 1.1e-73 247.0 0.0 1.2e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CNH PF00780.22 CAR22862.1 - 5.5e-76 255.8 0.2 1.1e-75 254.8 0.1 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 CAR22862.1 - 2.5e-41 140.9 0.2 1.3e-40 138.7 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 CAR22862.1 - 4.4e-31 108.5 0.1 4.4e-31 108.5 0.1 2.1 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.21 CAR22862.1 - 2.5e-14 53.1 0.0 6.1e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FlgN PF05130.12 CAR22862.1 - 0.044 14.3 2.4 1.2 9.7 0.1 2.6 2 0 0 2 2 2 0 FlgN protein ELO PF01151.18 CAR22863.1 - 1.8e-60 204.6 24.3 2.3e-60 204.3 24.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-C2H2_4 PF13894.6 CAR22864.1 - 1.5e-07 31.6 24.3 0.00074 20.1 1.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR22864.1 - 0.00022 21.4 0.3 0.081 13.2 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-SNAP50_C PF12251.8 CAR22864.1 - 0.00045 20.0 2.9 0.0082 15.8 0.2 2.1 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal zf-C2H2 PF00096.26 CAR22864.1 - 0.0017 18.7 2.5 0.0017 18.7 2.5 5.1 5 1 0 5 5 5 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR22864.1 - 0.0094 16.3 4.3 0.0094 16.3 4.3 4.9 4 1 1 5 5 5 1 Zinc-finger double domain Zn-C2H2_12 PF18112.1 CAR22864.1 - 0.012 16.0 0.3 6.8 7.2 0.1 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_6 PF13912.6 CAR22864.1 - 0.013 15.4 0.4 0.013 15.4 0.4 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 CAR22864.1 - 0.021 14.6 4.2 0.091 12.6 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.12 CAR22864.1 - 0.048 14.0 7.7 0.058 13.7 4.8 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 CAR22864.1 - 0.056 13.2 0.7 6.7 6.6 0.0 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF2256 PF10013.9 CAR22864.1 - 0.67 10.1 8.3 17 5.6 0.3 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Prok-RING_1 PF14446.6 CAR22864.1 - 0.9 9.5 4.6 7.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 CAR22864.1 - 6.6 6.9 8.1 51 4.1 0.4 3.5 3 0 0 3 3 3 0 Zinc ribbon domain FA_desaturase PF00487.24 CAR22865.1 - 1.1e-21 77.8 28.0 1.9e-21 77.1 28.0 1.4 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CAR22865.1 - 2.5e-06 27.7 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) KRE9 PF05390.11 CAR22867.1 - 4.4e-43 146.2 9.1 7.7e-43 145.4 9.1 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CAR22867.1 - 7.3e-15 55.5 0.1 1.2e-13 51.6 0.0 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Fn_bind PF02986.14 CAR22867.1 - 0.061 13.1 0.0 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 Fibronectin binding repeat La PF05383.17 CAR22868.1 - 1.4e-22 79.5 0.0 2.6e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CAR22868.1 - 5.2e-08 32.6 0.1 1.6e-07 31.0 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-REase-3 PF15647.6 CAR22868.1 - 0.061 13.6 2.0 0.14 12.5 0.1 2.4 3 0 0 3 3 3 0 Restriction endonuclease fold toxin 3 BRAP2 PF07576.12 CAR22868.1 - 0.094 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 SCVP PF17619.2 CAR22868.1 - 0.24 12.3 2.4 0.36 11.7 0.5 2.2 3 0 0 3 3 3 0 Secreted clade V proteins PSY3 PF16836.5 CAR22869.1 - 3.5e-54 183.6 0.6 4e-54 183.4 0.6 1.0 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description IstB_IS21 PF01695.17 CAR22869.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Aldo_ket_red PF00248.21 CAR22870.1 - 1.3e-43 149.3 0.0 1.6e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acyltransferase PF01553.21 CAR22871.1 - 1.4e-34 118.6 0.0 2.5e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Apolipo_F PF15148.6 CAR22871.1 - 0.089 12.3 0.5 0.17 11.4 0.5 1.4 1 0 0 1 1 1 0 Apolipoprotein F Lip_A_acyltrans PF03279.13 CAR22871.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase Glyco_trans_1_3 PF13528.6 CAR22871.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ThiS PF02597.20 CAR22871.1 - 0.44 11.2 2.5 1.2 9.9 2.5 1.7 1 0 0 1 1 1 0 ThiS family FBPase PF00316.20 CAR22872.1 - 5.5e-82 273.8 0.2 7.1e-82 273.5 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CPSF73-100_C PF11718.8 CAR22873.1 - 0.089 12.3 0.7 0.1 12.1 0.7 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term MFS_1 PF07690.16 CAR22874.1 - 3.4e-15 55.8 27.6 3.4e-15 55.8 27.6 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily ZYG-11_interact PF05884.12 CAR22874.1 - 0.36 10.2 8.0 0.025 14.0 1.7 2.0 2 0 0 2 2 2 0 Interactor of ZYG-11 CCB1 PF12046.8 CAR22874.1 - 0.78 9.1 5.3 0.76 9.1 0.4 2.9 2 1 0 2 2 2 0 Cofactor assembly of complex C subunit B SecY PF00344.20 CAR22875.1 - 7.2e-64 215.9 10.7 9.6e-64 215.5 10.7 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CAR22875.1 - 7.6e-18 64.1 0.2 4.2e-17 61.7 0.2 2.4 1 0 0 1 1 1 1 Plug domain of Sec61p SdpI PF13630.6 CAR22875.1 - 0.2 11.8 0.2 0.2 11.8 0.2 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF2975 PF11188.8 CAR22875.1 - 0.87 9.5 9.9 0.078 12.9 1.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Transp_cyt_pur PF02133.15 CAR22876.1 - 3.5e-155 517.1 37.2 4e-155 516.9 37.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NTP_transferase PF00483.23 CAR22877.1 - 3.8e-54 183.9 0.0 5.2e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CAR22877.1 - 2.5e-10 40.9 0.0 3.5e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 CAR22877.1 - 3.7e-09 36.0 5.6 2.2e-07 30.4 1.4 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CAR22877.1 - 0.00016 20.0 0.3 0.00023 19.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CAR22877.1 - 0.00096 18.9 1.4 0.13 12.0 0.3 3.2 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 CAR22877.1 - 0.084 12.6 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Fucokinase PF07959.12 CAR22877.1 - 0.16 10.9 0.1 1.3 7.8 0.1 2.0 2 0 0 2 2 2 0 L-fucokinase Ank_4 PF13637.6 CAR22878.1 - 4.9e-12 46.1 0.7 2.6e-05 24.7 0.4 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR22878.1 - 1.4e-09 38.4 0.5 0.0012 19.4 0.1 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR22878.1 - 3.7e-08 33.5 0.6 0.0038 17.5 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 CAR22878.1 - 4.3e-07 29.8 1.3 1.9e-06 27.7 0.3 2.5 2 1 0 2 2 2 1 KilA-N domain Ank PF00023.30 CAR22878.1 - 5.3e-05 23.5 0.2 0.63 10.6 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CAR22878.1 - 6.6e-05 23.0 0.2 0.086 13.4 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat DUF844 PF05815.11 CAR22878.1 - 0.031 13.5 1.2 0.042 13.0 0.5 1.6 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) Cytochrom_B562 PF07361.11 CAR22878.1 - 0.063 13.9 3.1 0.12 13.1 1.3 2.4 1 1 0 1 1 1 0 Cytochrome b562 AT_hook PF02178.19 CAR22878.1 - 5.2 7.3 7.1 16 5.8 7.1 1.9 1 0 0 1 1 1 0 AT hook motif Y_phosphatase3 PF13350.6 CAR22879.1 - 1.1e-60 205.5 0.1 1.7e-60 204.9 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 CAR22879.1 - 0.00014 21.2 0.1 0.00024 20.5 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAR22879.1 - 0.0019 17.9 0.1 0.013 15.1 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR22879.1 - 0.015 15.9 0.0 0.034 14.7 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1262 PF06880.11 CAR22879.1 - 0.15 12.5 0.0 0.63 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1262) CRAL_TRIO PF00650.20 CAR22880.1 - 6.2e-44 149.5 0.0 9.5e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR22880.1 - 4.4e-13 49.2 0.0 1.7e-12 47.3 0.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CAR22880.1 - 2.7e-06 27.6 0.0 6.6e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CENP-I PF07778.11 CAR22881.1 - 1.1e-06 27.7 0.7 1.1e-06 27.7 0.7 1.8 2 0 0 2 2 2 1 Mis6 tRNA-synt_1 PF00133.22 CAR22882.1 - 4.7e-51 173.7 0.6 4.4e-32 111.1 1.6 6.1 3 1 1 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CAR22882.1 - 1.9e-41 141.6 0.0 3e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CAR22882.1 - 2.4e-23 82.5 1.1 6.5e-18 64.6 0.1 4.8 4 1 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CAR22882.1 - 1.2e-05 25.3 0.4 3e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DNA_ligase_ZBD PF03119.16 CAR22882.1 - 0.022 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1d PF00750.19 CAR22882.1 - 0.031 13.2 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1c PF00749.21 CAR22882.1 - 0.071 12.0 0.1 6.3 5.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Zn-ribbon_8 PF09723.10 CAR22882.1 - 0.11 12.6 2.0 0.47 10.6 0.1 2.7 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 CAR22882.1 - 0.53 9.8 3.0 0.98 8.9 0.4 2.3 2 0 0 2 2 2 0 zinc-ribbon domain SMC_N PF02463.19 CAR22883.1 - 3.1e-18 66.0 22.3 4.2e-17 62.3 22.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CAR22883.1 - 3.6e-18 66.4 0.1 3.6e-18 66.4 0.1 3.4 2 2 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.6 CAR22883.1 - 7.5e-10 39.6 27.9 7.5e-10 39.6 27.9 4.9 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.6 CAR22883.1 - 3e-07 30.5 4.7 0.0015 18.4 0.5 2.8 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR22883.1 - 0.00068 19.3 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CTP-dep_RFKase PF01982.16 CAR22883.1 - 0.0074 16.4 0.0 0.065 13.3 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF120 Ploopntkinase3 PF18751.1 CAR22883.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 CAR22883.1 - 0.15 12.5 0.1 0.15 12.5 0.1 4.9 3 2 1 4 4 4 0 ABC transporter CarD_CdnL_TRCF PF02559.16 CAR22883.1 - 0.55 11.0 4.8 5 7.9 0.1 3.7 3 0 0 3 3 3 0 CarD-like/TRCF domain Uso1_p115_head PF04869.14 CAR22884.1 - 2.4e-92 309.4 5.5 2.9e-92 309.2 3.1 2.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CAR22884.1 - 1e-15 58.2 31.5 1e-15 58.2 31.5 13.7 2 1 14 16 16 16 2 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 CAR22884.1 - 0.00059 19.9 25.5 0.00059 19.9 25.5 12.7 1 1 11 13 13 13 3 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 CAR22884.1 - 0.001 16.7 62.4 0.001 16.7 62.4 4.6 1 1 3 4 4 4 1 Protein of unknown function (DUF3584) Tup_N PF08581.10 CAR22884.1 - 0.0014 18.9 6.7 0.0014 18.9 6.7 15.2 4 4 11 17 17 17 4 Tup N-terminal Arm_vescicular PF18770.1 CAR22884.1 - 0.02 14.8 0.0 0.049 13.6 0.0 1.7 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor Trans_reg_C PF00486.28 CAR22884.1 - 0.35 11.0 3.2 21 5.3 0.2 4.1 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal Filament PF00038.21 CAR22884.1 - 7 6.1 205.4 0.057 13.0 51.5 8.0 2 1 4 7 7 7 0 Intermediate filament protein Rad52_Rad22 PF04098.15 CAR22885.1 - 1.7e-35 122.2 0.2 2.1e-35 121.9 0.2 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.12 CAR22886.1 - 0 1120.5 0.1 0 1120.2 0.1 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 CAR22886.1 - 0.0057 16.9 2.9 0.79 10.1 0.7 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L21e PF01157.18 CAR22886.1 - 0.014 15.3 0.1 0.062 13.2 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L21e Tom37 PF10568.9 CAR22886.1 - 0.056 13.7 1.4 0.13 12.6 0.2 2.3 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein SWC7 PF17330.2 CAR22887.1 - 1.2e-37 127.9 0.3 1.5e-37 127.6 0.3 1.1 1 0 0 1 1 1 1 SWR1 chromatin-remodelling complex, sub-unit Swc7 Imm5 PF14423.6 CAR22887.1 - 0.14 12.4 0.1 0.92 9.7 0.0 1.9 1 1 1 2 2 2 0 Immunity protein Imm5 Vac14_Fig4_bd PF11916.8 CAR22888.1 - 9.6e-71 237.1 6.7 2.3e-70 235.9 6.7 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CAR22888.1 - 1.2e-45 154.0 4.1 9.1e-38 128.8 0.0 5.4 7 0 0 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CAR22888.1 - 2.2e-12 46.1 0.9 0.0013 18.8 0.0 6.1 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 CAR22888.1 - 7e-06 26.4 1.3 0.083 13.4 0.1 4.7 4 0 0 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 CAR22888.1 - 1.7e-05 25.0 7.9 0.75 9.8 1.1 4.4 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR22888.1 - 0.0026 18.1 0.3 9.2 6.7 0.0 4.3 4 1 0 4 4 4 1 HEAT repeats Dopey_N PF04118.14 CAR22888.1 - 0.0061 15.7 4.2 0.51 9.4 0.5 3.3 3 0 0 3 3 3 2 Dopey, N-terminal RTP1_C1 PF10363.9 CAR22888.1 - 0.099 12.8 2.0 0.73 10.0 0.4 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 CAR22888.1 - 1.7 9.1 9.0 0.54 10.7 0.3 4.2 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf-C2H2_2 PF12756.7 CAR22889.1 - 3.2e-32 110.9 1.7 7.3e-29 100.1 0.2 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) YvbH_ext PF11724.8 CAR22889.1 - 0.11 12.8 1.3 0.8 10.1 0.6 2.3 2 0 0 2 2 2 0 YvbH-like oligomerisation region RIBIOP_C PF04950.12 CAR22890.1 - 2e-105 352.4 0.3 6.2e-105 350.8 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CAR22890.1 - 1.2e-24 86.2 0.1 2.8e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CDC27 PF09507.10 CAR22890.1 - 0.39 10.0 0.0 0.39 10.0 0.0 2.9 3 0 0 3 3 3 0 DNA polymerase subunit Cdc27 Ribosomal_S14 PF00253.21 CAR22891.1 - 3e-17 62.1 2.8 3.3e-17 62.0 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.12 CAR22891.1 - 0.068 13.5 1.8 7.1 7.0 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Peptidase_M16_M PF16187.5 CAR22892.1 - 6.3e-85 284.9 3.8 6.3e-85 284.9 3.8 1.8 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CAR22892.1 - 1.5e-39 135.4 0.1 7e-39 133.2 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAR22892.1 - 5.7e-33 114.5 1.7 4.2e-23 82.3 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain UQ_con PF00179.26 CAR22895.1 - 3.6e-44 149.8 0.1 4.1e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR22895.1 - 0.00033 20.4 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CAR22895.1 - 0.68 10.2 3.8 1.7 9.0 3.8 1.9 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 CAR22896.1 - 2.3e-61 207.7 9.0 2.3e-61 207.7 9.0 1.6 1 1 1 2 2 2 1 Pex19 protein family XPC-binding PF09280.11 CAR22896.1 - 0.041 13.6 0.6 0.15 11.9 0.1 2.3 2 0 0 2 2 2 0 XPC-binding domain GET2 PF08690.10 CAR22896.1 - 0.13 11.9 13.9 0.18 11.4 3.7 2.2 1 1 1 2 2 2 0 GET complex subunit GET2 DNA_ligase_A_N PF04675.14 CAR22896.1 - 0.32 11.3 2.1 14 6.0 0.4 2.6 2 0 0 2 2 2 0 DNA ligase N terminus CFEM PF05730.11 CAR22897.1 - 8.6e-10 38.6 13.3 2.2e-09 37.3 13.3 1.7 1 0 0 1 1 1 1 CFEM domain Arrestin_N PF00339.29 CAR22898.1 - 6.4e-10 39.3 0.1 2.8e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.14 CAR22899.1 - 2.4e-94 315.4 0.0 2.8e-94 315.2 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Iso_dh PF00180.20 CAR22901.1 - 1.1e-64 218.8 0.0 1.3e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase COX7C PF02935.16 CAR22902.1 - 3.2e-24 85.0 1.9 3.7e-24 84.8 1.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Haem_degrading PF03928.14 CAR22904.1 - 5.9e-28 97.3 0.0 7.1e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Sec1 PF00995.23 CAR22905.1 - 9.9e-78 262.8 0.0 1.2e-77 262.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family AAA PF00004.29 CAR22906.1 - 7.7e-89 294.9 0.0 6.7e-44 149.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR22906.1 - 7.7e-27 92.8 2.6 2.1e-13 49.8 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CAR22906.1 - 9.8e-14 51.4 0.0 6.3e-06 26.0 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR22906.1 - 2.4e-12 47.5 1.3 1.1e-06 29.1 0.1 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CAR22906.1 - 2.5e-10 40.5 0.0 0.00064 19.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR22906.1 - 2.6e-09 37.5 1.2 0.00051 20.3 0.1 4.4 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 CAR22906.1 - 4.4e-09 36.7 0.0 0.0026 17.9 0.0 3.3 2 2 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CAR22906.1 - 4.9e-08 33.3 0.0 0.001 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CAR22906.1 - 5e-08 32.5 0.3 0.0072 15.6 0.0 3.2 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_14 PF13173.6 CAR22906.1 - 5.2e-07 29.7 0.0 0.0016 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 CAR22906.1 - 2.3e-05 24.3 0.0 0.0034 17.3 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.15 CAR22906.1 - 2.4e-05 24.3 0.0 0.028 14.3 0.1 3.1 2 1 0 2 2 2 1 Rad17 P-loop domain Mg_chelatase PF01078.21 CAR22906.1 - 3.4e-05 23.3 0.1 0.1 11.9 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CAR22906.1 - 4.1e-05 23.9 0.0 0.35 11.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_11 PF13086.6 CAR22906.1 - 0.00014 21.7 0.0 0.058 13.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 CAR22906.1 - 0.00016 21.7 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CAR22906.1 - 0.00025 21.3 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CAR22906.1 - 0.0004 20.3 0.0 0.85 9.7 0.0 3.4 4 0 0 4 4 3 1 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 CAR22906.1 - 0.00043 19.8 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 CAR22906.1 - 0.0005 20.0 0.1 0.033 14.1 0.0 3.4 3 0 0 3 3 3 1 NACHT domain IstB_IS21 PF01695.17 CAR22906.1 - 0.00085 19.1 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 CAR22906.1 - 0.0016 18.1 3.3 1.7 8.2 0.0 4.0 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.6 CAR22906.1 - 0.0017 18.9 0.0 0.22 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CAR22906.1 - 0.0018 18.2 0.0 2.7 7.8 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.18 CAR22906.1 - 0.0019 18.4 1.4 0.0043 17.2 0.4 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activ_2 PF14532.6 CAR22906.1 - 0.0031 17.6 0.0 0.43 10.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 CAR22906.1 - 0.0058 17.1 0.0 0.46 11.0 0.0 2.8 3 0 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.12 CAR22906.1 - 0.011 15.1 0.1 3.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CAR22906.1 - 0.011 15.4 0.3 0.15 11.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 CAR22906.1 - 0.013 15.3 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CAR22906.1 - 0.025 14.9 1.2 0.42 11.0 0.1 2.9 2 1 1 3 3 2 0 AAA domain Sigma54_activat PF00158.26 CAR22906.1 - 0.038 13.7 0.0 19 4.9 0.0 3.6 3 1 0 3 3 3 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CAR22906.1 - 0.038 13.7 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 CAR22906.1 - 0.053 12.9 0.2 16 4.7 0.0 3.2 3 0 0 3 3 3 0 KaiC AFG1_ATPase PF03969.16 CAR22906.1 - 0.072 12.0 0.0 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase DUF815 PF05673.13 CAR22906.1 - 0.074 12.2 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 CAR22906.1 - 0.12 11.9 0.5 2.7 7.5 0.0 2.6 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DSHCT PF08148.12 CAR22908.1 - 1e-48 165.1 0.3 3.2e-48 163.5 0.3 1.9 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 CAR22908.1 - 1.7e-41 141.2 0.2 5.1e-41 139.6 0.3 1.7 2 0 0 2 2 2 1 Ski2 N-terminal region DEAD PF00270.29 CAR22908.1 - 1.7e-20 73.5 0.0 4.5e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 CAR22908.1 - 4.9e-16 59.5 2.9 4.9e-16 59.5 2.9 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.31 CAR22908.1 - 5e-08 33.3 0.0 3e-07 30.8 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR22908.1 - 3.4e-06 27.2 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR22908.1 - 0.094 13.0 0.0 0.75 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Bromodomain PF00439.25 CAR22909.1 - 9.3e-40 134.6 0.8 2.6e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CAR22909.1 - 1.1e-18 67.1 1.5 3.6e-18 65.5 0.5 2.4 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation YabA PF06156.13 CAR22909.1 - 1.4 9.6 3.4 1.4 9.6 1.3 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF4094 PF13334.6 CAR22909.1 - 2.3 8.7 4.4 0.88 10.0 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Bap31 PF05529.12 CAR22910.1 - 1.4e-40 138.3 6.8 2e-40 137.7 6.8 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CAR22910.1 - 0.0012 18.8 1.6 0.002 18.1 1.6 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain ArAE_2_N PF10337.9 CAR22910.1 - 0.019 14.0 5.4 0.61 9.1 3.6 2.1 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Cast PF10174.9 CAR22910.1 - 0.028 12.7 0.2 0.036 12.3 0.2 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Topoisom_I PF01028.20 CAR22910.1 - 0.038 13.2 0.1 0.062 12.5 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core DivIC PF04977.15 CAR22910.1 - 0.11 12.3 0.6 0.38 10.6 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Dus PF01207.17 CAR22911.1 - 4.8e-46 157.3 0.0 4.7e-35 121.2 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 CAR22911.1 - 8e-06 25.5 4.8 0.0086 15.9 0.1 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 CAR22911.1 - 0.0033 17.3 0.2 0.0033 17.3 0.2 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAR22911.1 - 0.013 15.5 4.5 0.022 14.8 0.2 2.5 2 0 0 2 2 2 0 Zinc finger domain Lustrin_cystein PF14625.6 CAR22911.1 - 0.24 11.8 2.6 12 6.3 0.4 2.8 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain zf-CCCH_2 PF14608.6 CAR22911.1 - 0.47 11.0 4.2 1.1 9.9 0.2 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CAR22911.1 - 3.4 8.4 6.5 9.4 7.0 1.1 3.0 1 1 1 2 2 2 0 Torus domain MIF4G_like_2 PF09090.11 CAR22911.1 - 3.6 7.0 8.4 2.2 7.7 2.6 2.5 2 1 0 2 2 2 0 MIF4G like zf-C2H2_aberr PF17017.5 CAR22912.1 - 7.3e-05 23.0 5.8 0.0046 17.1 0.3 2.6 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CAR22912.1 - 0.0011 19.6 12.9 0.058 14.2 0.6 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR22912.1 - 0.0016 18.7 17.0 0.02 15.3 1.1 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.7 CAR22912.1 - 0.18 12.2 4.0 3.4 8.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CAR22912.1 - 0.3 11.6 19.4 0.23 12.0 1.6 3.6 3 0 0 3 3 3 0 Zinc-finger double domain Seipin PF06775.14 CAR22913.1 - 0.00085 19.5 0.1 0.0033 17.6 0.1 1.9 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DNA_pol_B_thumb PF14791.6 CAR22913.1 - 0.11 12.7 0.1 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase beta thumb DUF1765 PF08578.10 CAR22914.1 - 2.4e-19 70.0 8.3 8.2e-19 68.3 8.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) BRE1 PF08647.11 CAR22915.1 - 7.5e-26 90.0 15.8 7.5e-26 90.0 15.8 6.9 5 1 1 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CAR22915.1 - 1.7e-08 34.1 10.6 2.9e-08 33.4 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR22915.1 - 9.5e-07 28.6 12.0 1.9e-06 27.6 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR22915.1 - 3.2e-06 26.9 9.8 6.2e-06 26.0 9.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAR22915.1 - 2.4e-05 24.2 13.6 4.4e-05 23.3 13.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR22915.1 - 7.1e-05 22.6 14.3 0.00014 21.7 14.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR22915.1 - 0.00061 20.1 12.1 0.0011 19.2 12.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CAR22915.1 - 0.0066 16.5 10.2 0.014 15.4 10.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C2H2_jaz PF12171.8 CAR22915.1 - 0.02 15.2 0.3 1.8 8.9 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CAR22915.1 - 0.039 14.4 0.0 0.039 14.4 0.0 2.9 4 0 0 4 4 2 0 Zinc finger, C2H2 type zf-C3HC4_4 PF15227.6 CAR22915.1 - 1.7 8.9 10.1 3.6 7.8 10.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CAR22915.1 - 1.7 8.5 10.8 3.4 7.5 10.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Dus PF01207.17 CAR22916.1 - 1.3e-83 280.7 0.0 1.6e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ribosomal_L31e PF01198.19 CAR22917.1 - 2.3e-40 136.7 0.8 2.8e-40 136.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Rxt3 PF08642.10 CAR22918.1 - 6.7e-25 88.3 0.3 1.4e-22 80.8 0.2 2.7 1 1 1 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 CAR22918.1 - 0.016 15.3 0.0 0.19 11.9 0.0 2.4 1 1 0 1 1 1 0 LCCL domain DUF4050 PF13259.6 CAR22919.1 - 3.8e-09 37.1 0.2 3.8e-09 37.1 0.2 3.0 1 1 2 3 3 3 2 Protein of unknown function (DUF4050) GCN5L1 PF06320.13 CAR22920.1 - 0.00036 20.7 3.8 0.0017 18.5 3.8 2.0 1 1 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) GPAT_N PF14829.6 CAR22920.1 - 0.12 12.3 0.9 7.3 6.7 0.0 2.2 1 1 1 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal Vps39_1 PF10366.9 CAR22921.1 - 3.5e-32 110.9 0.5 3.5e-32 110.9 0.5 2.8 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CAR22921.1 - 3.9e-18 65.9 0.7 1.6e-17 63.9 0.7 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CAR22921.1 - 0.017 15.0 5.8 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Region in Clathrin and VPS Utp21 PF04192.12 CAR22922.1 - 8.7e-76 254.5 1.7 8.7e-76 254.5 1.7 1.6 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CAR22922.1 - 2e-15 56.8 0.3 0.00035 20.8 0.0 6.2 6 1 0 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR22922.1 - 5.7e-10 39.6 17.3 2.3e-06 28.2 1.3 7.7 7 1 1 8 8 8 2 WD domain, G-beta repeat PQQ_2 PF13360.6 CAR22922.1 - 0.002 17.8 0.3 0.092 12.3 0.0 3.1 3 0 0 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.16 CAR22922.1 - 0.0024 16.5 0.0 0.033 12.7 0.1 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain CPSF_A PF03178.15 CAR22922.1 - 0.0062 15.9 0.2 0.029 13.7 0.1 2.2 1 1 2 3 3 3 1 CPSF A subunit region Med24_N PF11277.8 CAR22922.1 - 0.048 11.7 0.0 0.068 11.2 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Alpha-amyl_C PF09071.10 CAR22922.1 - 0.083 12.7 0.0 0.29 11.0 0.0 2.0 1 0 0 1 1 1 0 Alpha-amylase, C terminal His_Phos_2 PF00328.22 CAR22923.1 - 4.1e-140 467.5 0.2 5.3e-140 467.1 0.2 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CAR22923.1 - 1e-36 124.9 0.0 2.5e-36 123.7 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CAR22923.1 - 5.8e-09 35.8 0.1 2e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CAR22923.1 - 0.14 12.2 0.2 0.79 9.8 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Ctr PF04145.15 CAR22924.1 - 1.5e-36 126.2 0.3 2.4e-36 125.6 0.3 1.3 1 1 0 1 1 1 1 Ctr copper transporter family Pribosyl_synth PF14572.6 CAR22925.1 - 1e-41 143.0 1.9 1.5e-33 116.3 0.3 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CAR22925.1 - 3.7e-40 136.5 0.0 5.3e-39 132.8 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CAR22925.1 - 1.9e-07 30.7 0.1 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain SRR1 PF07985.12 CAR22926.1 - 2.6e-18 65.8 0.0 5.2e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 SRR1 DUF1729 PF08354.10 CAR22927.1 - 4.5e-160 532.3 0.0 6.9e-160 531.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 CAR22927.1 - 6.3e-104 347.9 0.0 9.5e-103 344.0 0.0 2.7 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 CAR22927.1 - 1e-45 155.1 0.0 3.3e-45 153.5 0.0 2.0 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 CAR22927.1 - 4.8e-38 131.3 0.1 1.1e-37 130.1 0.0 1.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 CAR22927.1 - 7e-38 129.0 0.0 1.7e-37 127.7 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 CAR22927.1 - 4.5e-36 123.7 0.0 1.1e-35 122.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 CAR22927.1 - 1.6e-14 54.2 0.0 6.3e-14 52.2 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Lipase_3 PF01764.25 CAR22927.1 - 0.17 11.7 0.2 8.3 6.3 0.0 3.2 3 0 0 3 3 3 0 Lipase (class 3) Voldacs PF03517.13 CAR22928.1 - 2.5e-23 82.8 0.0 3.6e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.16 CAR22929.1 - 1.6e-77 260.2 0.0 2.2e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CAR22929.1 - 5.6e-18 65.0 0.0 1.1e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GATA PF00320.27 CAR22930.1 - 2e-06 27.3 8.3 2e-06 27.3 8.3 2.8 3 0 0 3 3 3 1 GATA zinc finger Mtr2 PF10429.9 CAR22931.1 - 1.3e-63 213.9 0.0 1.4e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Abhydrolase_1 PF00561.20 CAR22932.1 - 3.2e-18 66.3 0.0 7e-18 65.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR22932.1 - 1.5e-09 38.8 0.1 1.8e-09 38.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR22932.1 - 0.00016 21.0 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EHN PF06441.12 CAR22932.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Ndr PF03096.14 CAR22932.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF915 PF06028.11 CAR22932.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) SUR7 PF06687.12 CAR22933.1 - 6.9e-21 74.8 11.1 2.4e-19 69.8 11.1 2.6 1 1 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.23 CAR22933.1 - 0.002 18.2 6.5 0.014 15.4 3.6 2.9 2 0 0 2 2 2 1 Membrane-associating domain SUR7 PF06687.12 CAR22934.1 - 1.1e-42 146.1 15.2 1.3e-42 145.8 15.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Polysacc_synt_C PF14667.6 CAR22934.1 - 0.98 9.5 13.9 2.4 8.2 4.5 2.8 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DUF3938 PF13074.6 CAR22934.1 - 2.7 8.3 8.7 11 6.3 0.9 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3938) ABC_membrane_2 PF06472.15 CAR22935.1 - 1.9e-60 204.5 7.7 3.7e-59 200.4 7.7 2.1 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CAR22935.1 - 3.9e-17 63.1 0.0 8.9e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAR22935.1 - 0.00011 22.1 0.0 0.00031 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR22935.1 - 0.022 14.2 0.1 0.17 11.3 0.1 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR22935.1 - 0.024 14.4 0.0 0.07 12.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CAR22935.1 - 0.057 13.9 6.9 0.074 13.5 3.7 2.6 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CAR22935.1 - 0.15 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sec20 PF03908.13 CAR22935.1 - 0.82 9.6 3.7 2.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Sec20 Vps36_ESCRT-II PF11605.8 CAR22936.1 - 3.5e-27 94.4 0.1 8.3e-27 93.2 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 CAR22936.1 - 5e-21 75.1 0.1 9.4e-21 74.2 0.1 1.5 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 CAR22936.1 - 5.1e-18 64.2 2.4 5.1e-18 64.2 2.4 2.6 1 1 1 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain GRAM PF02893.20 CAR22936.1 - 0.0007 19.5 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain PH_TFIIH PF08567.11 CAR22936.1 - 0.00079 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain zf-RanBP PF00641.18 CAR22936.1 - 0.037 13.4 7.1 0.59 9.5 1.7 2.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 CAR22936.1 - 0.17 12.0 0.2 0.17 12.0 0.2 3.1 3 1 1 4 4 4 0 Sec23/Sec24 zinc finger DZR PF12773.7 CAR22936.1 - 0.27 11.3 5.6 0.54 10.3 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 CAR22936.1 - 0.97 9.4 5.6 0.5 10.3 0.1 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Mo25 PF08569.11 CAR22937.1 - 8.5e-111 370.4 5.5 9.6e-111 370.3 5.5 1.0 1 0 0 1 1 1 1 Mo25-like Helicase_C PF00271.31 CAR22938.1 - 2.1e-15 57.0 0.3 9.8e-15 54.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CAR22938.1 - 3.1e-13 49.9 0.0 9.4e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 CAR22938.1 - 1e-11 45.1 2.9 3.7e-11 43.3 2.9 2.1 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 CAR22938.1 - 1.9e-09 37.5 0.2 4.5e-09 36.3 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 CAR22938.1 - 0.0013 18.3 0.0 0.0032 16.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 CAR22938.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CAR22938.1 - 0.0014 18.3 0.0 0.0034 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 CAR22938.1 - 0.0041 16.2 0.0 0.0077 15.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 CAR22938.1 - 0.01 15.2 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 CAR22938.1 - 0.045 13.3 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CAR22938.1 - 0.045 14.0 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CAR22938.1 - 0.048 14.2 0.0 0.048 14.2 0.0 3.1 2 1 1 3 3 2 0 AAA domain AAA_7 PF12775.7 CAR22938.1 - 0.067 12.7 0.0 0.25 10.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CAR22938.1 - 0.18 11.5 0.2 1.3 8.7 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain CDC73_C PF05179.14 CAR22939.1 - 2.4e-51 173.5 0.8 3.5e-51 173.0 0.8 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal MFS_1 PF07690.16 CAR22940.1 - 3.2e-28 98.7 17.6 5.2e-28 98.0 17.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4153 PF13687.6 CAR22940.1 - 0.02 14.5 1.6 0.02 14.5 1.6 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF4153) ERGIC_N PF13850.6 CAR22940.1 - 0.044 14.1 1.4 42 4.6 0.0 4.6 4 1 1 5 5 5 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pox_A14 PF05767.12 CAR22940.1 - 4.2 7.6 6.1 4 7.7 0.9 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 UPF0242 PF06785.11 CAR22940.1 - 6.5 6.8 8.2 0.95 9.5 0.0 3.2 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus EF-hand_1 PF00036.32 CAR22941.1 - 2.2e-24 83.1 11.5 1.5e-05 24.2 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CAR22941.1 - 1.4e-21 76.7 6.9 1.4e-12 47.9 2.4 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR22941.1 - 2.1e-20 70.8 5.4 7.6e-05 22.3 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CAR22941.1 - 1.2e-15 56.1 12.0 0.0026 17.2 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CAR22941.1 - 1.7e-10 40.6 12.4 0.013 15.4 0.2 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CAR22941.1 - 5.8e-06 26.2 10.0 0.049 13.6 0.5 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAR22941.1 - 1.1e-05 25.7 0.3 0.11 12.8 0.1 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CAR22941.1 - 0.002 18.4 0.1 2.7 8.4 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.17 CAR22942.1 - 1.7e-64 218.2 0.0 2.4e-64 217.7 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Amidohydro_2 PF04909.14 CAR22943.1 - 9.9e-07 28.8 0.0 2.7e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase DUF3627 PF12299.8 CAR22943.1 - 0.0089 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3627) RepB_primase PF16793.5 CAR22943.1 - 0.056 13.6 0.0 0.091 12.9 0.0 1.3 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid DUF3760 PF12586.8 CAR22943.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) RPN13_C PF16550.5 CAR22944.1 - 9e-06 25.8 0.0 1.1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 UCH-binding domain Proteasom_Rpn13 PF04683.13 CAR22945.1 - 4.8e-21 75.1 0.0 6.7e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CinA PF02464.17 CAR22946.1 - 2.6e-30 105.0 0.0 3.2e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Competence-damaged protein DHR-2 PF06920.13 CAR22947.1 - 7.7e-44 150.2 0.6 2e-43 148.8 0.6 1.8 1 0 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 CAR22947.1 - 6e-08 32.0 0.0 3.4e-07 29.5 0.0 2.1 1 1 0 1 1 1 1 DOCK N-terminus Flavi_propep PF01570.17 CAR22947.1 - 0.053 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Flavivirus polyprotein propeptide PP-binding PF00550.25 CAR22948.1 - 2.5e-13 50.2 0.2 3.2e-13 49.8 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CAR22948.1 - 6.1e-06 26.4 0.5 8.4e-06 25.9 0.5 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.12 CAR22948.1 - 0.026 15.0 0.3 0.036 14.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) LRR_4 PF12799.7 CAR22949.1 - 3.9e-33 112.9 41.3 1.9e-10 40.8 2.4 7.6 5 2 4 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR22949.1 - 8e-27 92.8 31.9 9.4e-10 38.1 5.7 6.4 3 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 CAR22949.1 - 3e-18 65.9 18.9 4e-10 39.5 4.4 4.8 1 1 5 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.6 CAR22949.1 - 6e-07 29.0 24.3 0.014 15.4 0.2 7.8 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 CAR22949.1 - 0.0038 17.6 33.5 4.9 8.1 0.1 9.9 9 2 0 9 9 9 3 Leucine Rich Repeat LRR_5 PF13306.6 CAR22949.1 - 0.0059 16.6 5.4 0.0064 16.5 0.5 2.6 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) tRNA-synt_2b PF00587.25 CAR22950.1 - 1e-43 149.4 0.0 2e-43 148.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CAR22950.1 - 5.7e-19 68.1 0.0 9.5e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.12 CAR22951.1 - 1.3e-85 288.0 22.2 1.4e-85 287.8 22.2 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 AcylCoA_dehyd_C PF12186.8 CAR22951.1 - 0.0018 18.4 6.8 0.074 13.2 0.0 4.4 3 1 2 5 5 5 1 Acyl-CoA dehydrogenase C terminal Bap31_Bap29_C PF18035.1 CAR22951.1 - 0.035 14.1 0.1 0.035 14.1 0.1 3.0 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Sucrose_synth PF00862.19 CAR22951.1 - 0.043 12.1 6.1 0.051 11.9 5.2 1.6 1 1 0 1 1 1 0 Sucrose synthase DUF5344 PF17279.2 CAR22951.1 - 0.059 13.9 9.3 4.7 7.9 2.1 4.3 1 1 2 4 4 4 0 Family of unknown function (DUF5344) OmpH PF03938.14 CAR22951.1 - 0.066 13.5 0.5 0.066 13.5 0.5 3.6 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 CAR22951.1 - 0.077 13.0 15.0 0.19 11.8 0.2 4.3 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 CAR22951.1 - 0.25 11.5 18.2 0.024 14.8 4.4 3.7 2 1 1 3 3 3 0 Tropomyosin like WXG100 PF06013.12 CAR22951.1 - 0.3 11.4 11.2 2.6 8.4 0.2 4.5 5 0 0 5 5 5 0 Proteins of 100 residues with WXG Abi_C PF14355.6 CAR22951.1 - 0.31 11.2 1.5 38 4.5 0.1 3.3 4 0 0 4 4 4 0 Abortive infection C-terminus DUF4771 PF15995.5 CAR22951.1 - 0.41 10.9 6.9 0.29 11.4 1.4 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4771) Ribosomal_S4 PF00163.19 CAR22951.1 - 0.91 10.5 3.1 1.3 9.9 0.4 2.5 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain Fib_alpha PF08702.10 CAR22951.1 - 1.2 9.3 19.8 1.2 9.3 0.3 4.3 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 CAR22951.1 - 1.6 9.0 14.2 1.9 8.8 0.2 4.9 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF948) DUF2779 PF11074.8 CAR22951.1 - 2.6 8.6 7.9 0.75 10.3 0.8 2.8 1 1 0 2 2 2 0 Domain of unknown function(DUF2779) AI-2E_transport PF01594.16 CAR22951.1 - 4 6.5 6.2 12 4.9 2.5 3.0 2 1 1 3 3 3 0 AI-2E family transporter G-patch PF01585.23 CAR22952.1 - 5.5e-14 51.8 0.6 1.1e-13 50.9 0.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CAR22952.1 - 3e-07 30.4 0.3 5.5e-07 29.6 0.3 1.4 1 0 0 1 1 1 1 G-patch domain GCFC PF07842.12 CAR22952.1 - 4.6e-06 26.5 0.0 8.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein CHCH PF06747.13 CAR22953.1 - 6.7e-08 32.5 3.3 1.5e-07 31.4 3.3 1.6 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CAR22953.1 - 0.011 16.2 3.2 0.025 15.0 3.2 1.6 1 0 0 1 1 1 0 GCK domain Phage_GPO PF05929.11 CAR22953.1 - 0.025 14.2 2.1 0.037 13.7 2.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase V_ATPase_I PF01496.19 CAR22953.1 - 0.48 8.3 2.1 0.73 7.7 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 CAR22953.1 - 1.1 7.9 2.0 1.4 7.6 2.0 1.2 1 0 0 1 1 1 0 Presenilin Synaptobrevin PF00957.21 CAR22954.1 - 3.9e-15 55.4 0.7 6.1e-15 54.8 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CAR22954.1 - 8.3e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CNH PF00780.22 CAR22955.1 - 9.5e-15 54.9 1.5 2.3e-14 53.6 1.1 1.8 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 CAR22955.1 - 2.8e-07 30.9 0.0 8.6e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CAR22955.1 - 6.9e-07 29.4 3.3 4.4e-06 26.8 3.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CAR22955.1 - 0.003 18.1 1.4 0.017 15.6 1.4 2.5 1 1 0 1 1 1 1 PH domain adh_short PF00106.25 CAR22956.1 - 1e-33 116.5 0.0 1.6e-33 115.8 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR22956.1 - 2.1e-24 86.4 0.0 2.8e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR22956.1 - 1.2e-08 35.0 0.2 4.5e-07 30.0 0.2 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CAR22956.1 - 0.0003 20.3 0.0 0.0006 19.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR22956.1 - 0.05 12.6 0.1 0.066 12.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dak1_2 PF13684.6 CAR22956.1 - 0.082 12.0 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family SPC25 PF06703.11 CAR22957.1 - 7.8e-37 126.6 4.9 8.9e-37 126.4 4.9 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-RING_UBOX PF13445.6 CAR22958.1 - 2.5e-08 33.8 3.0 5.3e-08 32.8 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR22958.1 - 5.1e-07 29.5 4.3 1.5e-06 28.0 4.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR22958.1 - 8e-06 25.7 5.4 2.5e-05 24.1 5.4 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CAR22958.1 - 2.9e-05 24.3 6.7 8e-05 22.9 6.7 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CAR22958.1 - 0.00034 20.4 8.6 0.0041 16.9 8.6 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR22958.1 - 0.00057 19.7 2.7 0.00057 19.7 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR22958.1 - 0.00062 19.6 12.9 0.56 10.1 9.2 3.1 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CAR22958.1 - 0.0014 18.8 3.3 0.0014 18.8 3.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING IBR PF01485.21 CAR22958.1 - 0.67 10.2 2.9 12 6.2 0.0 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF1899 PF08953.11 CAR22959.1 - 4.6e-35 119.3 0.4 9.1e-35 118.4 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CAR22959.1 - 1.1e-19 70.3 7.4 3.5e-05 24.5 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_4 PF16300.5 CAR22959.1 - 1.1e-17 63.7 0.3 2.4e-17 62.6 0.3 1.6 1 0 0 1 1 1 1 Type of WD40 repeat Nup160 PF11715.8 CAR22959.1 - 1.6e-09 36.9 0.3 2.4e-05 23.2 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CAR22959.1 - 2.9e-08 33.9 0.3 0.023 15.0 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR22959.1 - 0.0027 17.6 0.0 0.077 12.9 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR22959.1 - 0.034 13.1 0.0 0.65 8.9 0.0 2.4 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CAR22959.1 - 0.04 12.5 0.1 0.062 11.8 0.1 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain SEN1_N PF12726.7 CAR22960.1 - 1.1e-194 648.9 18.9 1.4e-194 648.5 18.9 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 CAR22960.1 - 6.7e-72 242.4 0.2 6.7e-72 242.4 0.2 2.8 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 CAR22960.1 - 4.9e-63 212.4 0.0 1.2e-62 211.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR22960.1 - 2.3e-09 37.3 0.0 2.1e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CAR22960.1 - 2e-08 34.7 0.0 1.4e-07 32.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAR22960.1 - 1.6e-05 24.8 0.0 0.036 13.8 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CAR22960.1 - 0.00082 19.0 6.7 0.22 11.0 0.0 3.8 3 1 0 4 4 4 2 UvrD/REP helicase N-terminal domain Arteri_nucleo PF01481.16 CAR22961.1 - 0.14 12.4 0.5 0.31 11.3 0.5 1.6 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein EDR1 PF14381.6 CAR22961.1 - 0.17 11.6 0.2 0.35 10.6 0.2 1.5 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 ISG65-75 PF11727.8 CAR22961.1 - 0.34 10.1 2.9 0.41 9.8 0.9 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein DivIC PF04977.15 CAR22961.1 - 0.74 9.6 5.1 5 7.0 0.1 2.8 2 0 0 2 2 2 0 Septum formation initiator IMPDH PF00478.25 CAR22962.1 - 1.1e-134 448.9 4.4 1.3e-134 448.6 4.4 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CAR22962.1 - 5.2e-15 55.6 0.0 2.6e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CAR22962.1 - 5.4e-08 32.2 2.8 5.4e-08 32.2 2.8 1.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CAR22962.1 - 9.3e-06 25.2 7.3 0.0004 19.9 2.4 2.8 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 CAR22962.1 - 0.00033 20.2 1.1 0.003 17.1 0.2 2.4 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CAR22962.1 - 0.0016 17.8 1.2 0.0037 16.6 1.0 1.7 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 CAR22962.1 - 0.009 15.4 0.1 0.031 13.7 0.1 1.9 1 0 0 1 1 1 1 KDPG and KHG aldolase ADH_zinc_N PF00107.26 CAR22962.1 - 0.19 11.7 1.7 5.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Metallophos PF00149.28 CAR22963.1 - 1.4e-35 123.6 0.0 2.6e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WGG PF10273.9 CAR22964.1 - 1.1e-28 99.7 0.5 2.2e-28 98.7 0.5 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Hid1 PF12722.7 CAR22965.1 - 1.8e-84 284.5 22.2 1.2e-72 245.3 13.6 3.4 3 2 0 3 3 3 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CAR22965.1 - 3.4e-26 91.9 14.1 1.8e-20 73.0 1.1 3.0 2 1 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein RNR_inhib PF08591.10 CAR22966.1 - 1e-06 30.0 0.8 3.8e-06 28.2 0.8 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.21 CAR22967.1 - 5.7e-118 394.1 0.0 6.6e-118 393.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR22967.1 - 0.0082 15.4 0.0 0.022 14.0 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CAR22967.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II cNMP_binding PF00027.29 CAR22968.1 - 8.2e-26 89.9 0.0 7.9e-11 41.9 0.0 4.6 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain Patatin PF01734.22 CAR22968.1 - 2.5e-19 70.3 2.8 4.8e-18 66.1 2.8 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase PDZ_1 PF12812.7 CAR22968.1 - 0.15 12.1 0.1 0.53 10.3 0.1 1.9 1 0 0 1 1 1 0 PDZ-like domain LSM PF01423.22 CAR22969.1 - 8.4e-18 63.8 0.1 9.8e-18 63.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CAR22969.1 - 0.0082 16.3 0.0 0.015 15.4 0.0 1.5 1 1 1 2 2 2 1 RimP C-terminal SH3 domain MRP-L47 PF06984.13 CAR22970.1 - 1.7e-25 89.0 1.8 2.5e-25 88.4 0.7 1.9 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2884 PF11101.8 CAR22970.1 - 0.064 12.7 2.1 0.067 12.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) LBP_M PF17385.2 CAR22970.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain OGG_N PF07934.12 CAR22971.1 - 1.9e-22 79.6 0.1 3.7e-22 78.7 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CAR22971.1 - 7.3e-16 58.6 0.0 1.2e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Glucodextran_N PF09137.11 CAR22971.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Glucodextranase, domain N PIF1 PF05970.14 CAR22972.1 - 1.3e-66 225.3 1.1 5.3e-49 167.3 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CAR22972.1 - 2.4e-19 69.8 0.0 5.1e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR22972.1 - 5e-08 33.4 0.0 1.9e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR22972.1 - 9.9e-05 22.6 0.1 0.00057 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 CAR22972.1 - 0.00042 18.4 0.3 0.013 13.5 0.0 2.2 2 0 0 2 2 2 1 Helicase T2SSE PF00437.20 CAR22972.1 - 0.00079 18.6 0.1 0.0021 17.2 0.1 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.6 CAR22972.1 - 0.0027 17.5 0.0 0.0084 15.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain FtsK_SpoIIIE PF01580.18 CAR22972.1 - 0.014 14.8 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2950 PF11453.8 CAR22972.1 - 0.019 14.2 0.1 0.04 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) AAA_7 PF12775.7 CAR22972.1 - 0.025 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region SH3_13 PF18335.1 CAR22972.1 - 0.036 13.9 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Helicase_RecD PF05127.14 CAR22972.1 - 0.049 13.5 0.2 0.42 10.5 0.2 2.5 2 1 0 2 2 2 0 Helicase DUF349 PF03993.12 CAR22972.1 - 0.19 12.1 1.0 0.78 10.1 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Sec39 PF08314.11 CAR22973.1 - 2.8e-84 284.0 0.7 3.8e-61 207.5 0.4 2.0 2 0 0 2 2 2 2 Secretory pathway protein Sec39 THOC7 PF05615.13 CAR22974.1 - 3.8e-09 36.9 10.2 3.8e-09 36.9 10.2 2.8 2 1 0 2 2 2 1 Tho complex subunit 7 Microvir_H PF04687.12 CAR22974.1 - 0.02 14.3 0.2 0.031 13.7 0.2 1.4 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) DASH_Duo1 PF08651.10 CAR22974.1 - 0.11 12.3 4.9 0.1 12.4 1.2 2.6 2 1 1 3 3 3 0 DASH complex subunit Duo1 BLOC1_2 PF10046.9 CAR22974.1 - 0.18 12.1 10.5 0.68 10.3 5.2 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 CAR22974.1 - 0.2 11.7 10.8 0.24 11.4 4.3 2.6 2 0 0 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 CAR22974.1 - 0.62 10.2 11.5 3.3 7.9 4.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 CAR22974.1 - 1.9 8.3 12.1 2.2 8.1 2.4 3.4 2 1 1 3 3 3 0 Septum formation initiator DUF2508 PF10704.9 CAR22974.1 - 2.8 8.2 10.9 0.78 10.0 1.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) Ribosomal_S3Ae PF01015.18 CAR22975.1 - 7.2e-88 293.4 3.6 8.6e-88 293.2 3.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DLP_helical PF18709.1 CAR22975.1 - 0.018 14.2 0.3 0.028 13.6 0.3 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain SUI1 PF01253.22 CAR22975.1 - 0.057 13.9 0.1 0.15 12.6 0.1 1.9 1 1 0 1 1 1 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 CAR22975.1 - 0.1 12.2 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ras PF00071.22 CAR22976.1 - 3.3e-31 108.1 0.0 3.9e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR22976.1 - 7.9e-21 74.5 0.0 1.2e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR22976.1 - 2e-05 24.1 0.0 2.6e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR22976.1 - 0.00065 19.1 0.1 0.0008 18.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CAR22976.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CAR22976.1 - 0.0025 17.9 0.0 0.0042 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR22976.1 - 0.0046 16.5 0.0 0.035 13.6 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CAR22976.1 - 0.047 12.9 0.0 0.21 10.7 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit DLIC PF05783.11 CAR22976.1 - 0.18 10.6 0.6 3 6.5 0.1 2.3 1 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_lid_10 PF17872.1 CAR22977.1 - 2.8e-35 120.4 0.1 8.9e-35 118.8 0.1 1.9 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 CAR22977.1 - 3.2e-18 66.4 0.0 7.3e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 CAR22977.1 - 3.2e-09 36.7 0.1 2.8e-08 33.7 0.0 2.4 2 0 0 2 2 2 1 BAH domain AAA_16 PF13191.6 CAR22977.1 - 4.9e-09 36.8 0.1 1.2e-07 32.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAR22977.1 - 1.7e-07 31.6 0.1 3.4e-06 27.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 CAR22977.1 - 9.8e-05 22.4 3.7 0.00038 20.5 0.1 3.2 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 CAR22977.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 CAR22977.1 - 0.0089 16.4 0.0 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR22977.1 - 0.032 14.8 0.1 0.2 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAR22977.1 - 0.068 13.6 0.0 0.33 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SUR7 PF06687.12 CAR22978.1 - 4.8e-09 36.1 11.1 8.1e-09 35.4 11.1 1.5 1 1 0 1 1 1 1 SUR7/PalI family PIG-P PF08510.12 CAR22978.1 - 0.023 14.6 0.1 0.078 12.9 0.1 2.0 1 0 0 1 1 1 0 PIG-P DUF4227 PF14004.6 CAR22978.1 - 1.3 9.1 3.7 1.9 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4227) DUF5527 PF17665.1 CAR22979.1 - 2.6 7.6 5.3 6.8 6.2 1.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5527) COPIIcoated_ERV PF07970.12 CAR22980.1 - 5.2e-29 101.7 0.0 7.5e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAR22980.1 - 5.6e-24 84.3 0.0 5.6e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.21 CAR22982.1 - 8e-14 51.6 18.3 3.2e-08 33.7 3.1 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CAR22982.1 - 0.00071 19.9 8.5 0.00071 19.9 8.5 4.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 CAR22982.1 - 0.0019 18.0 8.9 0.0019 18.0 8.9 4.9 4 2 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR22982.1 - 0.0036 17.2 10.4 0.0036 17.2 10.4 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) POB3_N PF17292.2 CAR22983.1 - 6.7e-29 100.2 0.6 4.5e-27 94.3 0.1 2.9 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 CAR22983.1 - 7.5e-28 96.2 0.0 7.5e-28 96.2 0.0 3.0 4 0 0 4 4 4 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 CAR22983.1 - 1.8e-27 95.6 0.1 7e-24 84.1 0.0 3.6 4 0 0 4 4 4 2 Histone chaperone Rttp106-like AMA-1 PF02430.15 CAR22983.1 - 0.016 14.2 0.2 0.027 13.4 0.2 1.3 1 0 0 1 1 1 0 Apical membrane antigen 1 Dak1 PF02733.17 CAR22984.1 - 1.1e-108 362.8 0.2 1.6e-108 362.3 0.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CAR22984.1 - 1.3e-45 155.4 0.1 3.1e-45 154.2 0.1 1.7 1 0 0 1 1 1 1 DAK2 domain POC3_POC4 PF10448.9 CAR22984.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 SH3_1 PF00018.28 CAR22985.1 - 2e-14 52.9 0.0 4.6e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR22985.1 - 2e-13 49.9 0.0 5.1e-13 48.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CAR22985.1 - 2.4e-11 43.2 0.0 4.3e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Phytoreo_P8 PF07124.11 CAR22985.1 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Phytoreovirus outer capsid protein P8 Zn_clus PF00172.18 CAR22986.1 - 1.4e-05 25.1 10.8 2.3e-05 24.4 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_binding_2 PF13380.6 CAR22987.1 - 8.1e-25 87.6 0.0 9.6e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Hexokinase_1 PF00349.21 CAR22988.1 - 2.2e-21 76.7 0.0 3.3e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CAR22988.1 - 2.3e-14 53.4 0.1 2.4e-13 50.1 0.1 2.1 1 1 0 1 1 1 1 Hexokinase PTR2 PF00854.21 CAR22989.1 - 1e-50 172.8 1.6 1.5e-50 172.2 1.6 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 CAR22989.1 - 0.00031 19.8 38.7 0.0079 15.2 9.4 3.4 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CAR22989.1 - 0.099 11.5 6.1 0.36 9.6 0.9 2.5 2 1 0 2 2 2 0 MFS_1 like family LapA_dom PF06305.11 CAR22989.1 - 0.18 11.6 1.3 0.59 10.0 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Phage_holin_3_6 PF07332.11 CAR22989.1 - 0.19 11.8 0.2 0.19 11.8 0.2 3.9 4 1 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1455 PF07306.11 CAR22989.1 - 0.22 11.5 2.8 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) Cyt-b5 PF00173.28 CAR22990.1 - 2.6e-10 40.3 0.0 3.8e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain cNMP_binding PF00027.29 CAR22991.1 - 8.5e-38 128.3 0.0 6.2e-18 64.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_4 PF12799.7 CAR22991.1 - 1.6e-11 44.3 3.3 0.019 15.4 0.0 5.5 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CAR22991.1 - 6.1e-07 29.2 1.2 1.9e-06 27.7 1.2 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 CAR22991.1 - 8.3e-07 28.6 10.7 0.32 11.2 0.1 7.7 10 0 0 10 10 10 2 Leucine Rich repeat F-box PF00646.33 CAR22991.1 - 1.7e-06 27.7 2.7 8.7e-06 25.5 2.7 2.3 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 CAR22991.1 - 0.013 16.0 16.9 19 6.3 0.2 8.9 10 0 0 10 10 10 0 Leucine Rich Repeat CAP_N PF01213.19 CAR22991.1 - 0.19 11.2 5.3 3.2 7.1 2.2 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal vATP-synt_AC39 PF01992.16 CAR22992.1 - 4.5e-106 355.2 1.2 5e-106 355.0 1.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Dor1 PF04124.12 CAR22993.1 - 3.3e-22 78.6 2.2 9.1e-22 77.2 2.2 1.6 1 1 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 CAR22993.1 - 0.00022 21.1 0.4 0.0082 16.0 0.0 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec5 C2 PF00168.30 CAR22994.1 - 3.4e-61 204.0 4.8 2.5e-21 75.9 0.2 5.7 5 0 0 5 5 5 5 C2 domain DUF1491 PF07372.12 CAR22994.1 - 0.07 13.5 0.4 0.18 12.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) Ribosomal_L6e PF01159.19 CAR22996.1 - 6.2e-38 129.8 0.6 8e-38 129.4 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L6e FKBP_C PF00254.28 CAR22997.1 - 1.7e-28 98.8 0.0 5.4e-28 97.1 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CAR22997.1 - 3.1e-19 69.5 7.7 3.1e-19 69.5 7.7 3.1 2 2 0 2 2 2 1 Nucleoplasmin-like domain TAF4 PF05236.14 CAR22997.1 - 0.0062 16.3 12.0 0.0062 16.3 12.0 2.1 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family SDA1 PF05285.12 CAR22997.1 - 0.28 10.6 61.2 0.36 10.2 32.0 2.1 2 0 0 2 2 2 0 SDA1 DUF4045 PF13254.6 CAR22997.1 - 0.79 9.3 26.9 1 8.9 13.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF4228 PF14009.6 CAR22997.1 - 4.8 7.5 12.5 12 6.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CCSAP PF15748.5 CAR22997.1 - 6.6 6.8 32.7 6 7.0 18.0 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Mitofilin PF09731.9 CAR22997.1 - 8 5.2 36.4 1.3 7.8 7.7 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein GAGA_bind PF06217.12 CAR22997.1 - 8.8 6.5 22.9 5.5 7.2 2.0 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family HMG-CoA_red PF00368.18 CAR22998.1 - 1.2e-141 472.0 0.1 1.7e-141 471.5 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 CAR22998.1 - 1.1e-41 142.3 0.3 2.7e-41 141.0 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 CAR22998.1 - 3.7e-10 39.8 4.3 3.7e-10 39.8 4.3 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CAR22998.1 - 0.17 10.0 10.6 0.037 12.1 7.2 1.5 2 0 0 2 2 2 0 Patched family TBX PF12598.8 CAR22998.1 - 1.1 10.1 4.6 2.2 9.1 4.6 1.4 1 0 0 1 1 1 0 T-box transcription factor Zn_clus PF00172.18 CAR23001.1 - 0.00065 19.8 11.8 0.0011 19.0 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_c3_2 PF14537.6 CAR23001.1 - 0.022 15.2 3.5 0.044 14.3 3.5 1.4 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.6 CAR23001.1 - 0.11 12.5 2.9 0.24 11.4 2.9 1.5 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Sybindin PF04099.12 CAR23002.1 - 5.9e-19 68.4 0.0 7.6e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family ENTH PF01417.20 CAR23003.1 - 1.7e-43 147.7 0.1 2.4e-43 147.1 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CAR23003.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 ANTH domain MAGI_u5 PF16666.5 CAR23003.1 - 0.042 14.0 3.9 0.094 12.9 3.9 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI Pro_isomerase PF00160.21 CAR23004.1 - 3.2e-46 157.5 0.1 3.7e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDE6_gamma PF04868.12 CAR23004.1 - 0.064 13.5 1.2 13 6.1 0.0 2.7 3 1 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit MARVEL PF01284.23 CAR23005.1 - 1.5e-09 38.0 16.5 2.1e-09 37.5 16.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.16 CAR23006.1 - 5.7e-32 111.0 50.9 1.6e-25 89.8 21.3 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR23006.1 - 9.9e-09 34.2 16.1 6.3e-06 24.9 5.8 3.1 3 0 0 3 3 3 3 Fungal trichothecene efflux pump (TRI12) HRXXH PF13933.6 CAR23007.1 - 2.7e-87 292.4 0.0 3.1e-87 292.2 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 CAR23007.1 - 5.6e-08 33.4 0.0 1e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Flocculin PF00624.18 CAR23008.1 - 0 1977.1 1397.1 2.6e-15 56.3 24.3 49.9 49 1 0 49 49 49 47 Flocculin repeat Candida_ALS_N PF11766.8 CAR23008.1 - 1.6e-55 188.1 1.4 1.6e-55 188.1 1.4 3.2 3 0 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding MVL PF12151.8 CAR23008.1 - 3.7 7.5 34.8 12 5.9 0.5 8.6 7 0 0 7 7 7 0 Mannan-binding protein Lant_dehydr_C PF14028.6 CAR23008.1 - 4.1 6.8 18.0 2.3 7.7 0.2 5.5 2 2 5 7 7 7 0 Lantibiotic biosynthesis dehydratase C-term GLEYA PF10528.9 CAR23009.1 - 9.9e-25 86.8 0.7 9.9e-25 86.8 0.7 3.1 3 0 0 3 3 3 1 GLEYA domain PA14 PF07691.12 CAR23009.1 - 2.2e-13 50.2 2.4 6.3e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 PA14 domain Flocculin PF00624.18 CAR23009.1 - 0.0029 17.8 22.0 0.0029 17.8 22.0 4.0 4 1 0 4 4 4 2 Flocculin repeat Aminotran_4 PF01063.19 CAR23011.1 - 3.1e-35 122.1 0.0 3.9e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV 5-FTHF_cyc-lig PF01812.20 CAR23012.1 - 2.5e-40 138.3 0.0 2.9e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family GST_C_3 PF14497.6 CAR23013.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SET PF00856.28 CAR23014.1 - 5.5e-15 56.1 0.4 1.3e-14 54.9 0.0 1.8 2 0 0 2 2 2 1 SET domain HSF_DNA-bind PF00447.17 CAR23015.1 - 2.6e-31 108.1 7.4 5.7e-31 107.0 7.4 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 CAR23015.1 - 1.6e-27 95.9 0.5 6.1e-27 94.0 0.4 2.0 2 0 0 2 2 2 1 Response regulator receiver domain ZapB PF06005.12 CAR23015.1 - 0.04 14.4 1.6 0.11 12.9 1.6 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Pkinase PF00069.25 CAR23016.1 - 1.4e-66 224.6 0.0 2.1e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23016.1 - 1.3e-30 106.5 0.0 2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CAR23016.1 - 2.1e-11 44.0 0.0 1.2e-06 28.7 0.0 2.7 1 1 1 2 2 2 2 C2 domain Pkinase_C PF00433.24 CAR23016.1 - 2.7e-09 37.6 2.2 2.7e-09 37.6 2.2 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 CAR23016.1 - 2.9e-09 36.7 0.0 1.8e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CAR23016.1 - 0.00092 18.3 0.0 0.0034 16.4 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CAR23016.1 - 0.0084 15.7 0.1 0.48 10.0 0.1 2.6 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CAR23016.1 - 0.09 12.3 0.0 0.42 10.1 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Glyco_hydro_47 PF01532.20 CAR23017.1 - 1.9e-119 399.6 0.0 3.5e-119 398.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 Ribosomal_S4e PF00900.20 CAR23018.1 - 4.8e-38 128.9 0.6 1.4e-37 127.4 0.5 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CAR23018.1 - 2.2e-25 88.0 0.0 3.9e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CAR23018.1 - 3.1e-20 72.0 7.9 9e-20 70.5 7.9 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CAR23018.1 - 8.6e-09 35.0 0.0 2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CAR23018.1 - 3.4e-05 23.6 1.8 3.4e-05 23.6 1.8 3.1 4 0 0 4 4 4 1 KOW motif Sipho_tail PF05709.11 CAR23018.1 - 0.041 13.3 0.2 0.1 12.0 0.2 1.7 1 1 0 1 1 1 0 Phage tail protein dCache_2 PF08269.11 CAR23018.1 - 0.17 11.0 0.0 0.46 9.6 0.0 1.7 1 1 0 2 2 2 0 Cache domain 5_nucleotid_C PF02872.18 CAR23019.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Mgm101p PF06420.12 CAR23020.1 - 3e-85 284.0 0.0 3.7e-85 283.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PMT PF02366.18 CAR23021.1 - 9.3e-78 261.2 20.2 1.6e-77 260.4 20.2 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR23021.1 - 3.2e-61 206.4 4.9 3.2e-61 206.4 4.9 3.5 2 1 2 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR23021.1 - 3.3e-26 92.3 0.5 5.1e-26 91.7 0.5 1.2 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 CAR23021.1 - 3.9e-05 23.9 13.4 3.9e-05 23.9 13.4 2.7 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PHO4 PF01384.20 CAR23021.1 - 0.0097 15.0 0.8 3 6.8 0.0 2.4 2 0 0 2 2 2 2 Phosphate transporter family DUF4743 PF15916.5 CAR23022.1 - 1.8e-07 31.2 0.1 2.9e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CAR23022.1 - 2.1e-06 27.8 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Arrestin_N PF00339.29 CAR23022.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DHHA2 PF02833.14 CAR23023.1 - 2.5e-32 112.0 0.1 7.3e-32 110.5 0.1 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 CAR23023.1 - 2.1e-09 37.6 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 DHH family HECT_2 PF09814.9 CAR23024.1 - 2e-73 247.4 0.9 2.3e-73 247.3 0.9 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4973 PF16343.5 CAR23025.1 - 0.097 12.7 5.1 4.2 7.4 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4973) Homoserine_dh PF00742.19 CAR23026.1 - 2e-52 177.6 0.0 2.7e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CAR23026.1 - 2.1e-18 67.1 0.0 3.5e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IML1 PF12257.8 CAR23027.1 - 5.8e-102 340.7 0.2 1.5e-101 339.3 0.2 1.7 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CAR23027.1 - 4e-25 87.6 0.4 9.5e-25 86.5 0.4 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) VWA_2 PF13519.6 CAR23028.1 - 2.1e-20 73.3 0.2 1.6e-19 70.5 0.0 2.2 1 1 2 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 CAR23028.1 - 8.6e-10 38.7 0.0 1.1e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 CAR23028.1 - 0.02 14.8 0.7 0.048 13.6 0.7 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif PDH PF02153.17 CAR23028.1 - 0.099 11.6 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase HNOBA PF07701.14 CAR23028.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated NIR_SIR PF01077.22 CAR23029.1 - 1.2e-50 171.1 0.1 6.3e-48 162.3 0.1 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 CAR23029.1 - 1.7e-28 99.6 0.0 3.3e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 CAR23029.1 - 5.8e-28 96.6 0.1 7.1e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Arg_decarbox_C PF17944.1 CAR23029.1 - 0.15 12.6 0.1 49 4.6 0.2 3.6 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Chalcone_2 PF16035.5 CAR23030.1 - 2.4e-68 229.9 0.0 3e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 CAR23030.1 - 0.0087 16.2 0.1 1.1 9.4 0.1 2.2 1 1 1 2 2 2 2 Chalcone isomerase-like Indigoidine_A PF04227.12 CAR23031.1 - 2.4e-119 398.0 0.1 3.1e-119 397.7 0.1 1.1 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CAR23031.1 - 1.8e-09 37.4 0.0 1.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Tti2 PF10521.9 CAR23032.1 - 1.2e-47 162.8 0.1 1.9e-47 162.1 0.1 1.3 1 0 0 1 1 1 1 Tti2 family zf-Tim10_DDP PF02953.15 CAR23033.1 - 1.5e-20 72.6 5.2 1.9e-20 72.2 5.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RIX1 PF08167.12 CAR23035.1 - 2.7e-47 160.9 5.0 1.6e-46 158.4 3.9 2.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TMF_TATA_bd PF12325.8 CAR23036.1 - 1.6e-31 108.9 18.1 1.6e-31 108.9 18.1 5.7 2 1 2 4 4 4 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CAR23036.1 - 1.2e-15 57.3 18.6 1.2e-15 57.3 18.6 9.1 4 3 5 9 9 9 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 CAR23036.1 - 0.0075 16.3 85.2 0.79 9.7 4.8 6.7 3 2 2 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 CAR23036.1 - 0.016 15.6 1.3 0.016 15.6 1.3 8.7 7 2 4 11 11 11 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 CAR23036.1 - 0.034 14.2 1.2 0.034 14.2 1.2 7.8 4 3 3 7 7 7 0 Centrosome localisation domain of PPC89 FPP PF05911.11 CAR23036.1 - 0.1 10.8 78.1 0.016 13.4 28.8 3.1 1 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil GAS PF13851.6 CAR23036.1 - 0.22 10.9 70.6 0.36 10.1 29.7 4.0 3 2 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 CAR23036.1 - 3.1 7.9 37.6 2.9 7.9 0.5 5.3 4 3 2 6 6 6 0 Protein of unknown function (DUF1664) Filament PF00038.21 CAR23036.1 - 4.6 6.7 63.7 1.2 8.6 28.6 4.4 2 1 1 3 3 3 0 Intermediate filament protein Pribosyltran PF00156.27 CAR23037.1 - 1.9e-11 43.8 0.1 2.5e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Utp12 PF04003.12 CAR23038.1 - 1.8e-06 28.2 0.4 3.1e-06 27.4 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Lge1 PF11488.8 CAR23038.1 - 0.17 12.1 3.1 0.44 10.8 3.1 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 IBN_N PF03810.19 CAR23039.1 - 2.3e-12 46.6 0.0 3.5e-11 42.9 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 CAR23039.1 - 0.23 10.2 13.2 0.11 11.3 5.9 3.4 3 1 1 4 4 4 0 Cse1 DUF5535 PF17687.1 CAR23040.1 - 0.082 13.1 0.0 14 5.9 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5535) MDM31_MDM32 PF08118.11 CAR23041.1 - 2.9e-224 745.6 1.8 5.7e-224 744.6 1.8 1.4 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins NAC PF01849.18 CAR23042.1 - 1.1e-19 70.2 0.4 3.3e-19 68.6 0.1 2.0 2 0 0 2 2 2 1 NAC domain zinc_ribbon_10 PF10058.9 CAR23043.1 - 3.9e-14 52.1 0.2 8e-14 51.1 0.2 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein NicO PF03824.16 CAR23043.1 - 0.00013 21.4 0.3 0.0002 20.8 0.3 1.2 1 0 0 1 1 1 1 High-affinity nickel-transport protein HemX PF04375.14 CAR23043.1 - 0.006 15.9 2.4 0.006 15.9 2.4 1.9 2 0 0 2 2 2 1 HemX, putative uroporphyrinogen-III C-methyltransferase V-SNARE PF05008.15 CAR23043.1 - 0.014 15.8 7.2 0.13 12.7 4.3 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus zf-ribbon_3 PF13248.6 CAR23043.1 - 0.026 13.9 1.8 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 CAR23043.1 - 0.064 13.0 3.0 0.52 10.1 3.0 2.2 1 1 0 1 1 1 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 CAR23043.1 - 0.091 13.2 0.6 20 5.8 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Cys_rich_CPCC PF14206.6 CAR23043.1 - 0.097 12.5 0.2 0.2 11.5 0.2 1.6 1 0 0 1 1 1 0 Cysteine-rich CPCC Rubredoxin PF00301.20 CAR23043.1 - 0.13 12.3 0.4 0.13 12.3 0.4 1.6 2 0 0 2 2 1 0 Rubredoxin zf-C2H2_4 PF13894.6 CAR23043.1 - 0.15 13.0 2.1 1.2 10.2 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 CAR23043.1 - 0.21 11.2 4.9 8.4 6.1 0.1 3.2 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 CAR23043.1 - 0.24 11.0 1.3 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2 PF00096.26 CAR23043.1 - 0.28 11.7 3.4 1.7 9.2 0.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nudix_N_2 PF14803.6 CAR23043.1 - 0.39 10.7 2.8 0.28 11.2 0.7 1.8 2 0 0 2 2 2 0 Nudix N-terminal YlqD PF11068.8 CAR23043.1 - 0.57 10.6 8.4 2.9 8.3 0.3 2.3 2 0 0 2 2 2 0 YlqD protein zf-C2H2_3rep PF18868.1 CAR23043.1 - 0.65 10.7 4.9 1.3 9.7 0.3 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats FliD_N PF02465.18 CAR23043.1 - 0.71 10.6 6.7 3 8.6 0.2 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF4200 PF13863.6 CAR23043.1 - 1.1 9.6 13.9 6.3 7.2 8.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2072 PF09845.9 CAR23043.1 - 2.9 8.2 5.8 1.8 8.8 0.5 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein APG6_N PF17675.1 CAR23043.1 - 6.8 7.2 13.7 1.7e+02 2.7 13.7 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Ctf8 PF09696.10 CAR23044.1 - 7.6e-21 74.9 2.6 1.8e-18 67.2 2.6 2.1 1 1 0 1 1 1 1 Ctf8 Ig_C19orf38 PF17737.1 CAR23044.1 - 0.15 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Ig domain in C19orf38 (HIDE1) Glyco_hydro_47 PF01532.20 CAR23045.1 - 5e-149 497.1 1.2 5.7e-149 496.9 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cys_Met_Meta_PP PF01053.20 CAR23046.1 - 2.6e-25 88.8 0.0 2e-24 85.9 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CAR23046.1 - 0.0046 16.2 0.0 0.0084 15.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PDE6_gamma PF04868.12 CAR23046.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit ATP-synt_J PF04911.12 CAR23047.1 - 4.5e-29 99.8 0.9 5e-29 99.6 0.9 1.0 1 0 0 1 1 1 1 ATP synthase j chain DUF3185 PF11381.8 CAR23047.1 - 0.065 13.3 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Allantoicase PF03561.15 CAR23048.1 - 2e-94 313.2 0.1 1.6e-47 161.1 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Methyltransf_16 PF10294.9 CAR23049.1 - 8.6e-20 71.2 0.0 1.6e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 CAR23049.1 - 3e-05 24.6 0.0 0.0025 18.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CAR23049.1 - 0.0026 17.2 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CAR23049.1 - 0.0029 17.2 0.0 0.0078 15.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CAR23049.1 - 0.02 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF5332 PF17266.2 CAR23049.1 - 0.039 13.6 0.3 0.067 12.9 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5332) Methyltransf_12 PF08242.12 CAR23049.1 - 0.041 14.6 0.1 0.27 12.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain zf-C2H2 PF00096.26 CAR23052.1 - 7.8e-07 29.2 13.8 0.00029 21.1 1.8 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR23052.1 - 2.7e-05 24.4 7.5 0.00033 20.9 4.4 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR23052.1 - 0.00013 22.5 12.5 0.0049 17.6 1.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger Dus PF01207.17 CAR23053.1 - 2.3e-80 270.0 0.0 2.9e-80 269.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Tom37_C PF11801.8 CAR23053.1 - 0.039 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain Cupin_5 PF06172.11 CAR23054.1 - 3.7e-41 140.6 0.0 4.9e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) TFR_dimer PF04253.15 CAR23055.1 - 3.1e-16 59.6 0.0 7.6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CAR23055.1 - 4e-16 59.3 0.0 7.8e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CAR23055.1 - 3.2e-09 36.7 0.0 6.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 PA domain MFS_1 PF07690.16 CAR23056.1 - 3.8e-06 26.1 49.1 0.0002 20.4 49.1 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR23056.1 - 0.00076 18.5 10.0 0.00076 18.5 10.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Flocculin PF00624.18 CAR23057.1 - 2.7e-52 174.7 133.3 1.3e-15 57.3 28.4 12.3 12 2 1 13 13 13 4 Flocculin repeat GLEYA PF10528.9 CAR23057.1 - 5.5e-24 84.4 0.0 5.2e-23 81.3 0.0 2.9 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 CAR23057.1 - 5.6e-11 42.5 0.0 1.9e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 PA14 domain MFS_1 PF07690.16 CAR23058.1 - 1.4e-28 99.9 24.7 1.4e-28 99.9 24.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Ost5 PF05251.12 CAR23058.1 - 0.36 11.1 0.1 0.36 11.1 0.1 4.9 7 0 0 7 7 7 0 Oligosaccharyltransferase subunit 5 IU_nuc_hydro PF01156.19 CAR23059.1 - 3.8e-36 125.2 0.1 4.8e-36 124.9 0.1 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ATP-synt_DE_N PF02823.16 CAR23059.1 - 0.049 13.5 0.2 5.5 7.0 0.0 3.0 3 1 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Transketolase_C PF02780.20 CAR23059.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain Fungal_trans_2 PF11951.8 CAR23060.1 - 1.9e-44 152.1 0.0 2.3e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23060.1 - 0.00012 22.1 12.8 0.00025 21.1 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApbA_C PF08546.11 CAR23061.1 - 3.8e-32 111.1 0.0 1.1e-31 109.6 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CAR23061.1 - 3.7e-25 88.3 0.0 5.5e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.21 CAR23062.1 - 2.7e-46 158.1 0.0 1e-44 153.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Flocculin PF00624.18 CAR23063.1 - 1.2e-89 294.3 233.2 5.2e-16 58.6 26.8 14.9 14 2 1 15 15 15 7 Flocculin repeat GLEYA PF10528.9 CAR23063.1 - 2.8e-19 69.3 0.0 7.1e-18 64.8 0.0 3.6 1 1 0 1 1 1 1 GLEYA domain PHO4 PF01384.20 CAR23064.1 - 9.1e-117 389.9 14.4 1.1e-116 389.6 14.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tautomerase PF01361.21 CAR23064.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Tautomerase enzyme Ferritin_2 PF13668.6 CAR23065.1 - 3.6e-39 134.1 0.7 4.9e-39 133.6 0.7 1.2 1 0 0 1 1 1 1 Ferritin-like domain DIOX_N PF14226.6 CAR23066.1 - 7.7e-29 100.8 0.1 2.4e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CAR23066.1 - 2e-12 47.5 0.0 3.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CN_hydrolase PF00795.22 CAR23067.1 - 2.3e-45 155.0 0.0 2.7e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans PF04082.18 CAR23068.1 - 7.1e-39 133.4 1.3 1e-38 132.9 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 CAR23069.1 - 1.5e-81 274.1 0.0 1.9e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF1445 PF07286.12 CAR23070.1 - 1.9e-30 105.7 0.0 2.5e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Fungal_trans PF04082.18 CAR23071.1 - 5.6e-12 45.2 2.1 1.1e-11 44.3 2.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23071.1 - 0.00083 19.4 12.9 0.0016 18.5 12.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CAR23072.1 - 9.8e-41 139.8 25.0 1.2e-40 139.5 25.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Hydantoinase_B PF02538.14 CAR23073.1 - 9.5e-208 690.8 0.1 1.2e-207 690.4 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CAR23073.1 - 6.3e-101 337.5 0.2 1.4e-100 336.4 0.2 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CAR23073.1 - 1.4e-53 181.3 0.1 9e-52 175.4 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.16 CAR23074.1 - 2.1e-29 102.5 36.5 2.1e-29 102.5 36.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR23074.1 - 0.0014 17.1 4.9 0.0023 16.4 4.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AA_permease PF00324.21 CAR23075.1 - 1.8e-81 274.2 39.2 2.3e-81 273.8 39.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23075.1 - 5.8e-28 97.9 42.9 8.3e-28 97.4 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease PGF-CTERM PF18204.1 CAR23075.1 - 3.8 7.6 7.2 0.67 10.0 0.8 2.8 2 0 0 2 2 2 0 PGF-CTERM motif AAA_26 PF13500.6 CAR23076.1 - 3.8e-41 141.1 0.0 4.8e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CAR23076.1 - 0.041 13.9 0.1 0.12 12.4 0.1 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.11 CAR23076.1 - 0.078 12.3 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Aminotran_3 PF00202.21 CAR23077.1 - 4.3e-99 331.9 0.0 7.2e-99 331.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR23077.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Metallophos PF00149.28 CAR23078.1 - 2.4e-13 51.1 2.0 2.4e-13 51.1 2.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase CDC45 PF02724.14 CAR23079.1 - 2.5 6.3 10.4 3.3 5.9 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Thiolase_N PF00108.23 CAR23080.1 - 3e-78 262.8 0.2 4.1e-78 262.3 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CAR23080.1 - 4.9e-46 155.4 0.8 1e-45 154.3 0.8 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CAR23080.1 - 0.0013 18.4 0.5 0.017 14.7 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Elf4 PF07011.11 CAR23080.1 - 0.14 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain ACP_syn_III PF08545.10 CAR23080.1 - 1.4 8.8 4.9 1.5 8.8 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FH2 PF02181.23 CAR23081.1 - 2.1e-65 221.3 4.1 2.1e-65 221.3 4.1 3.2 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CAR23081.1 - 3.2e-14 52.9 0.0 3.2e-14 52.9 0.0 3.9 3 1 1 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 CAR23081.1 - 0.0009 18.9 4.2 0.0009 18.9 4.2 4.2 2 1 0 3 3 3 2 Diaphanous FH3 Domain MRI PF15325.6 CAR23081.1 - 0.22 12.6 1.4 1.2 10.3 1.4 2.2 1 0 0 1 1 1 0 Modulator of retrovirus infection SKG6 PF08693.10 CAR23082.1 - 0.0025 17.2 2.0 0.0025 17.2 2.0 2.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Coa1 PF08695.10 CAR23083.1 - 1.1e-39 134.9 0.0 1.3e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.10 CAR23084.1 - 4e-29 100.3 0.0 4.4e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Myb_DNA-binding PF00249.31 CAR23085.1 - 1.1e-28 99.1 13.2 7.1e-12 45.3 0.3 3.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR23085.1 - 3.7e-24 84.7 5.7 1.3e-09 38.1 0.6 4.5 3 2 1 4 4 4 3 Myb-like DNA-binding domain PAT1 PF09770.9 CAR23085.1 - 0.028 12.7 27.9 0.055 11.7 27.9 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tyrosinase PF00264.20 CAR23085.1 - 0.085 13.1 11.5 0.33 11.2 11.5 2.1 1 0 0 1 1 1 0 Common central domain of tyrosinase V_ATPase_I PF01496.19 CAR23085.1 - 2.8 5.8 15.7 4.2 5.2 15.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PepSY_TM PF03929.16 CAR23085.1 - 2.9 7.5 4.9 5.7 6.5 4.9 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Dicty_REP PF05086.12 CAR23085.1 - 4.3 5.2 12.0 7.1 4.5 12.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GREB1 PF15782.5 CAR23085.1 - 7.6 3.5 20.1 11 3.0 20.1 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer UCH PF00443.29 CAR23086.1 - 1.6e-58 198.2 4.9 3e-58 197.3 4.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR23086.1 - 8.2e-18 65.1 8.3 7.2e-17 62.0 8.3 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CAR23086.1 - 0.00044 20.7 0.0 0.0016 19.0 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain YppF PF14178.6 CAR23086.1 - 0.1 12.5 0.2 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 YppF-like protein zinc_ribbon_2 PF13240.6 CAR23086.1 - 1.6 8.6 3.5 20 5.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DAO PF01266.24 CAR23087.1 - 5.1e-52 177.6 0.0 8.6e-52 176.9 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CAR23087.1 - 2.8e-43 146.8 0.0 5.3e-43 145.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CAR23087.1 - 4.6e-11 42.5 5.6 3.1e-10 39.7 5.6 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CAR23087.1 - 1.7e-08 34.2 0.8 2.3e-05 23.9 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CAR23087.1 - 0.00021 20.7 0.8 0.0017 17.6 0.8 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAR23087.1 - 0.00061 19.0 0.4 0.0094 15.1 0.3 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CAR23087.1 - 0.0041 15.9 0.6 0.0065 15.2 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 CAR23087.1 - 0.0041 16.4 0.1 2.6 7.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain GMC_oxred_N PF00732.19 CAR23087.1 - 0.0058 16.0 0.6 0.0093 15.4 0.1 1.5 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CAR23087.1 - 0.012 15.8 2.2 0.022 15.0 0.4 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAR23087.1 - 0.07 12.4 0.1 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 CAR23087.1 - 0.17 11.7 2.0 0.45 10.4 1.1 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PTPA PF03095.15 CAR23089.1 - 1.2e-105 353.3 0.0 1.4e-105 353.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PEPCK_ATP PF01293.20 CAR23090.1 - 1.9e-214 712.6 0.0 2.2e-214 712.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CAR23090.1 - 0.049 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SelA PF03841.13 CAR23090.1 - 0.085 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase ATPase PF06745.13 CAR23090.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC PIN_4 PF13638.6 CAR23093.1 - 7.8e-15 55.3 0.4 1.7e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 PIN domain S6PP PF05116.13 CAR23093.1 - 0.037 13.5 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase HAUS2 PF15003.6 CAR23093.1 - 0.12 12.1 0.5 0.32 10.7 0.5 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 Pcc1 PF09341.10 CAR23094.1 - 8.1e-19 67.5 0.0 9.1e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DAGK_cat PF00781.24 CAR23095.1 - 4e-09 36.1 0.0 1.2e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain zf-primase PF09329.11 CAR23096.1 - 5.7e-12 45.2 2.0 8.3e-12 44.7 0.6 2.0 2 0 0 2 2 2 1 Primase zinc finger DUF5088 PF17008.5 CAR23096.1 - 0.00073 19.3 0.9 0.0024 17.6 0.1 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF5088) tRNA_anti-codon PF01336.25 CAR23096.1 - 0.004 17.1 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4140 PF13600.6 CAR23096.1 - 3.7 8.1 8.1 3.3 8.2 4.9 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tup_N PF08581.10 CAR23096.1 - 7.7 6.9 12.3 0.23 11.8 3.5 2.8 3 0 0 3 3 3 0 Tup N-terminal TPR_MLP1_2 PF07926.12 CAR23097.1 - 3.4e-31 108.0 26.5 3.4e-31 108.0 26.5 19.0 4 4 17 21 21 21 5 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 CAR23097.1 - 0.0031 17.9 5.7 0.0031 17.9 5.7 13.7 6 4 7 15 15 15 3 Bacterial type III secretion protein (HrpB7) Sas6_CC PF18594.1 CAR23097.1 - 0.26 11.1 0.0 0.26 11.1 0.0 6.3 7 0 0 7 7 7 0 Sas6/XLF/XRCC4 coiled-coil domain DUF2935 PF11155.8 CAR23097.1 - 0.62 10.4 51.2 9.2 6.6 0.0 12.2 3 3 5 9 9 9 0 Domain of unknown function (DUF2935) ubiquitin PF00240.23 CAR23098.1 - 3.8e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CAR23098.1 - 2e-29 101.3 10.9 3e-29 100.7 10.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CAR23098.1 - 2.1e-16 59.5 0.7 3e-16 59.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR23098.1 - 2.1e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CAR23098.1 - 0.0036 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAR23098.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR23098.1 - 0.0056 16.8 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CAR23098.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CAR23098.1 - 0.023 15.2 0.1 0.03 14.9 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CAR23098.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Response_reg PF00072.24 CAR23099.1 - 1.1e-27 96.3 0.2 2.2e-27 95.4 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CAR23099.1 - 6.5e-25 87.8 0.1 6e-19 68.6 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CAR23099.1 - 1.7e-11 44.0 1.4 2.5e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CAR23099.1 - 0.0026 18.1 0.8 0.18 12.2 0.2 2.6 2 0 0 2 2 2 1 HAMP domain Saf_2TM PF18303.1 CAR23099.1 - 0.074 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain AA_permease_2 PF13520.6 CAR23101.1 - 9.1e-68 229.0 40.4 1.1e-67 228.8 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease Pantoate_ligase PF02569.15 CAR23102.1 - 3.7e-93 311.6 0.0 4.2e-93 311.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ndc80_HEC PF03801.13 CAR23103.1 - 1.7e-50 170.6 1.1 1.7e-50 170.6 1.1 2.1 3 0 0 3 3 3 1 HEC/Ndc80p family DUF5595 PF18077.1 CAR23103.1 - 7.9e-11 41.9 2.9 7.9e-11 41.9 2.9 4.6 4 2 2 6 6 6 1 Domain of unknown function (DUF5595) Spc7 PF08317.11 CAR23103.1 - 3e-05 23.0 33.6 0.0068 15.3 8.1 2.6 2 0 0 2 2 2 2 Spc7 kinetochore protein Ins145_P3_rec PF08709.11 CAR23103.1 - 0.0061 15.8 0.8 0.016 14.4 0.8 1.7 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Fez1 PF06818.15 CAR23103.1 - 0.011 16.2 29.4 0.27 11.7 13.7 2.7 2 0 0 2 2 2 0 Fez1 NPV_P10 PF05531.12 CAR23103.1 - 0.012 16.0 0.4 0.012 16.0 0.4 5.4 5 1 1 6 6 5 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 CAR23103.1 - 0.023 13.8 27.1 0.11 11.5 13.1 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 CAR23103.1 - 0.037 13.6 38.7 0.16 11.5 13.6 3.8 2 1 1 3 3 3 0 Intermediate filament protein YqbF PF14553.6 CAR23103.1 - 0.051 13.4 1.8 14 5.7 0.1 3.8 5 0 0 5 5 4 0 YqbF, hypothetical protein domain YokU PF14122.6 CAR23103.1 - 0.061 13.3 0.1 0.24 11.4 0.1 2.0 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin RNase_PH_C PF03725.15 CAR23103.1 - 0.085 12.9 0.0 24 5.1 0.0 2.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 UPF0242 PF06785.11 CAR23103.1 - 0.33 11.0 37.4 0.05 13.7 15.7 3.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3130 PF11328.8 CAR23103.1 - 0.34 11.2 4.2 7.7 6.8 0.1 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3130 Cluap1 PF10234.9 CAR23103.1 - 0.6 9.5 0.0 0.6 9.5 0.0 5.1 3 2 1 5 5 5 0 Clusterin-associated protein-1 ERM PF00769.19 CAR23103.1 - 2.2 8.0 31.3 3.1 7.6 14.9 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family OmpH PF03938.14 CAR23103.1 - 3.6 7.9 43.7 12 6.2 0.1 4.3 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 CAR23103.1 - 3.7 7.3 30.4 0.7 9.7 6.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) PriC PF07445.12 CAR23103.1 - 3.8 7.4 28.9 2.1 8.3 8.1 2.9 2 1 0 2 2 2 0 Primosomal replication protein priC Golgin_A5 PF09787.9 CAR23103.1 - 3.8 6.9 34.0 0.1 12.1 14.2 2.8 2 1 0 2 2 2 0 Golgin subfamily A member 5 Wtap PF17098.5 CAR23103.1 - 9.2 6.2 25.9 3.8 7.4 0.5 4.0 1 1 2 3 3 3 0 WTAP/Mum2p family CENP-F_leu_zip PF10473.9 CAR23103.1 - 9.9 6.2 40.1 0.54 10.3 10.5 3.8 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERCC3_RAD25_C PF16203.5 CAR23104.1 - 1.1e-125 417.8 1.4 2.1e-125 416.9 1.4 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CAR23104.1 - 2.8e-36 124.5 0.1 6.5e-36 123.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR23104.1 - 5.3e-16 59.1 0.0 1.3e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAR23104.1 - 3.8e-12 46.5 0.1 9.3e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CAR23104.1 - 1.8e-09 36.8 0.0 2.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CAR23104.1 - 4.6e-05 23.3 0.0 9.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 CAR23104.1 - 0.035 13.5 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SRP40_C PF05022.12 CAR23105.1 - 1.5e-23 83.4 4.2 1.5e-23 83.4 4.2 3.0 3 1 0 3 3 3 1 SRP40, C-terminal domain Whi5 PF08528.11 CAR23106.1 - 1.8e-10 40.2 0.1 3.4e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Whi5 like LIM PF00412.22 CAR23107.1 - 2.4e-14 53.3 24.8 2e-08 34.3 7.8 2.3 2 0 0 2 2 2 2 LIM domain Peptidase_M48_N PF16491.5 CAR23108.1 - 6.9e-61 205.3 6.1 6.9e-61 205.3 6.1 2.0 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CAR23108.1 - 1.8e-43 148.6 0.0 2.9e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 CAR23108.1 - 0.028 14.0 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF2201_N PF13203.6 CAR23108.1 - 0.073 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain SprT-like PF10263.9 CAR23108.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 SprT-like family TRAM_LAG1_CLN8 PF03798.16 CAR23109.1 - 7.7e-34 117.2 19.6 1e-33 116.8 19.6 1.2 1 0 0 1 1 1 1 TLC domain PfkB PF00294.24 CAR23110.1 - 2.3e-73 247.2 1.9 2.6e-73 247.0 1.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CAR23110.1 - 0.00068 19.1 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Na_Ca_ex PF01699.24 CAR23111.1 - 2.6e-45 154.1 26.9 2.6e-27 95.6 9.3 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein KAR9 PF08580.10 CAR23111.1 - 0.3 9.6 0.5 0.44 9.0 0.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Lipase_3 PF01764.25 CAR23112.1 - 1.2e-33 115.9 0.0 2e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CAR23112.1 - 0.055 14.1 0.0 0.068 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family G-alpha PF00503.20 CAR23113.1 - 5.5e-103 344.8 0.5 7.2e-103 344.5 0.5 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CAR23113.1 - 9.6e-15 54.5 0.4 2.8e-10 39.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR23113.1 - 2.9e-05 23.5 1.0 0.0026 17.1 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CAR23113.1 - 0.0012 19.1 0.1 2 8.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 CAR23113.1 - 0.036 13.8 0.3 0.056 13.1 0.3 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF5137 PF17220.3 CAR23114.1 - 5.1e-18 65.7 0.0 5.7e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF5137) CPSase_L_D2 PF02786.17 CAR23115.1 - 1.8e-109 364.1 0.0 5.3e-84 280.9 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CAR23115.1 - 1.6e-38 131.8 0.1 3.3e-38 130.8 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CAR23115.1 - 3.6e-20 72.2 0.1 5.1e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CAR23115.1 - 4.3e-17 62.3 0.4 1.7e-07 31.0 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CAR23115.1 - 2.3e-15 56.5 0.0 1.9e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CAR23115.1 - 5.3e-06 26.6 0.1 0.032 14.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 CAR23115.1 - 7e-06 25.9 0.1 0.061 13.1 0.1 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 CAR23115.1 - 8.7e-05 22.1 0.0 0.066 12.7 0.1 2.8 2 1 0 2 2 2 2 ATP-grasp domain MGS PF02142.22 CAR23115.1 - 0.097 12.9 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 MGS-like domain GSH-S_ATP PF02955.16 CAR23115.1 - 0.17 11.3 0.0 0.45 9.9 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Aldo_ket_red PF00248.21 CAR23116.1 - 4e-50 170.7 0.0 4.6e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ComX PF05952.12 CAR23116.1 - 0.12 12.3 0.0 0.44 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Myb_DNA-binding PF00249.31 CAR23116.1 - 0.45 10.7 3.8 4.9 7.4 0.0 3.2 4 0 0 4 4 4 0 Myb-like DNA-binding domain OPT PF03169.15 CAR23117.1 - 1.3e-193 645.1 56.1 1.5e-193 644.9 56.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SNAP PF14938.6 CAR23118.1 - 7.3e-108 360.3 18.1 8.2e-108 360.1 18.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CAR23118.1 - 0.019 15.6 7.4 46 4.9 0.4 5.1 3 2 0 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 CAR23118.1 - 0.022 14.3 0.7 0.064 12.8 0.1 1.9 1 1 0 2 2 2 0 Foie gras liver health family 1 Spatacsin_C PF14649.6 CAR23118.1 - 0.088 11.9 1.8 0.44 9.6 1.5 2.0 1 1 1 2 2 2 0 Spatacsin C-terminus Ferric_reduct PF01794.19 CAR23119.1 - 2.2e-22 79.5 13.4 2.2e-22 79.5 13.4 2.8 3 1 1 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CAR23119.1 - 7.9e-22 78.0 0.0 1.6e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CAR23119.1 - 5e-21 74.8 0.1 1.1e-20 73.8 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Yippee-Mis18 PF03226.14 CAR23120.1 - 2.4e-13 50.2 7.4 2.9e-13 49.9 7.4 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myotub-related PF06602.14 CAR23121.1 - 3.9e-141 470.1 0.6 4.8e-141 469.8 0.6 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 CAR23121.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.20 CAR23121.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 GRAM domain DSPc PF00782.20 CAR23121.1 - 0.044 13.6 0.1 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR23121.1 - 0.057 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CMD PF02627.20 CAR23122.1 - 1.1e-06 28.6 0.0 8.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family HMMR_C PF15908.5 CAR23122.1 - 0.35 11.1 1.4 9.5 6.5 0.2 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Nnf1 PF03980.14 CAR23123.1 - 1.4e-27 96.3 6.8 1.4e-27 96.3 6.8 1.8 2 0 0 2 2 2 1 Nnf1 PTP2 PF17022.5 CAR23123.1 - 0.021 14.4 0.1 0.045 13.4 0.0 1.5 1 1 0 1 1 1 0 Polar tube protein 2 from Microsporidia LRRFIP PF09738.9 CAR23123.1 - 0.029 13.9 9.4 0.036 13.6 9.4 1.1 1 0 0 1 1 1 0 LRRFIP family HHH_6 PF14579.6 CAR23123.1 - 0.1 12.8 0.1 0.22 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif YlqD PF11068.8 CAR23123.1 - 0.22 11.9 6.8 0.18 12.2 5.3 1.8 1 1 0 1 1 1 0 YlqD protein FapA PF03961.13 CAR23123.1 - 0.25 9.9 3.1 0.33 9.5 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 CAR23123.1 - 3.9 7.5 5.8 1.8 8.6 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_23 PF13476.6 CAR23123.1 - 4 7.9 10.7 8 6.9 10.7 1.6 1 1 0 1 1 1 0 AAA domain Rho_Binding PF08912.11 CAR23123.1 - 4.2 8.3 10.3 6.6 7.6 2.2 3.0 3 0 0 3 3 3 0 Rho Binding EF-hand_4 PF12763.7 CAR23124.1 - 4.5e-34 116.5 1.1 1.5e-11 44.1 0.0 4.3 5 0 0 5 5 5 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 CAR23124.1 - 5.1e-08 32.7 0.0 1.5e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 CAR23124.1 - 3.7e-06 26.4 0.1 0.072 13.1 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CAR23124.1 - 2.5e-05 24.7 0.3 2.4 8.7 0.1 4.7 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CAR23124.1 - 3.7e-05 23.0 0.0 0.035 13.6 0.0 3.8 3 0 0 3 3 3 1 EF hand UBA_4 PF14555.6 CAR23124.1 - 0.0005 19.8 0.8 0.0016 18.2 0.1 2.3 2 0 0 2 2 2 1 UBA-like domain Filament PF00038.21 CAR23124.1 - 0.0033 17.1 50.0 0.029 13.9 17.6 3.3 1 1 2 3 3 3 3 Intermediate filament protein Spc7 PF08317.11 CAR23124.1 - 0.094 11.6 58.0 0.58 9.0 22.5 3.1 1 1 1 2 2 2 0 Spc7 kinetochore protein VanZ PF04892.12 CAR23125.1 - 7.7e-07 29.8 0.2 9.9e-07 29.5 0.2 1.2 1 0 0 1 1 1 1 VanZ like family Lys_export PF03956.13 CAR23125.1 - 0.056 13.0 0.7 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Lysine exporter LysO Ribosomal_S7 PF00177.21 CAR23126.1 - 2e-35 121.6 0.3 3.3e-35 120.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e PPP4R2 PF09184.11 CAR23127.1 - 3.4e-38 131.9 16.6 3.4e-38 131.9 16.6 3.1 1 1 1 2 2 2 1 PPP4R2 Peptidase_M16_C PF05193.21 CAR23128.1 - 4e-22 79.1 0.1 1.4e-21 77.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR23128.1 - 5.8e-18 65.3 0.7 1e-17 64.5 0.7 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) BUD22 PF09073.10 CAR23129.1 - 0.0089 15.4 9.7 0.011 15.1 9.7 1.1 1 0 0 1 1 1 1 BUD22 AF-4 PF05110.13 CAR23129.1 - 0.11 10.5 6.7 0.11 10.6 6.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CNDH2_C PF16858.5 CAR23129.1 - 0.27 11.1 4.4 0.31 10.9 4.4 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SURF2 PF05477.11 CAR23129.1 - 0.3 10.7 5.7 0.4 10.3 5.7 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SDA1 PF05285.12 CAR23129.1 - 0.41 10.0 13.2 0.54 9.6 13.2 1.2 1 0 0 1 1 1 0 SDA1 Peptidase_M20 PF01546.28 CAR23130.1 - 2.9e-26 92.5 0.0 4.7e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR23130.1 - 1.2e-12 47.7 0.0 2.2e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Proteasome PF00227.26 CAR23131.1 - 6.6e-37 126.9 0.0 5.3e-36 123.9 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.18 CAR23132.1 - 4.7e-49 167.0 12.0 8.1e-49 166.2 12.0 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Thioredoxin PF00085.20 CAR23133.1 - 3.4e-11 43.1 0.0 3.5e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 CAR23133.1 - 0.00077 19.6 0.0 0.01 16.0 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CAR23133.1 - 0.0031 18.0 0.0 0.82 10.1 0.0 3.1 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CAR23133.1 - 0.0036 16.7 0.0 0.008 15.6 0.0 1.5 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CAR23133.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein Sod_Cu PF00080.20 CAR23134.1 - 2.5e-46 157.4 4.8 3.1e-46 157.1 4.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTP_synth_N PF06418.14 CAR23135.1 - 9.1e-124 412.0 0.1 1.2e-123 411.6 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CAR23135.1 - 4.4e-58 196.2 0.0 6.7e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CAR23135.1 - 0.0086 15.9 0.1 0.067 12.9 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 CAR23135.1 - 0.091 12.6 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family CbiA PF01656.23 CAR23135.1 - 0.18 11.8 0.0 0.53 10.3 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SIKE PF05769.11 CAR23136.1 - 0.64 9.9 10.6 7.2 6.5 10.5 2.3 1 1 0 1 1 1 0 SIKE family KIAA1430 PF13879.6 CAR23136.1 - 0.66 10.8 8.3 3.3 8.5 8.3 2.1 1 1 0 1 1 1 0 KIAA1430 homologue DUF4407 PF14362.6 CAR23136.1 - 1 8.6 5.3 1.3 8.3 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4164 PF13747.6 CAR23136.1 - 8.6 6.7 16.0 0.045 14.0 6.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) ESCRT-II PF05871.12 CAR23137.1 - 3.6e-43 147.2 1.7 3.9e-43 147.1 0.9 1.4 2 0 0 2 2 2 1 ESCRT-II complex subunit Nmad4 PF18756.1 CAR23137.1 - 0.019 15.3 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 Nucleotide modification associated domain 4 Sod_Fe_C PF02777.18 CAR23138.1 - 5.2e-17 61.9 1.2 1e-14 54.5 1.2 2.4 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Scramblase PF03803.15 CAR23139.1 - 3.8e-65 219.3 0.0 6.7e-64 215.2 0.0 2.0 1 1 0 1 1 1 1 Scramblase Peptidase_C12 PF01088.21 CAR23140.1 - 3.8e-56 190.2 0.0 6.3e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CAR23140.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases SHOCT PF09851.9 CAR23140.1 - 0.0023 17.6 0.8 0.0023 17.6 0.8 2.8 3 0 0 3 3 3 1 Short C-terminal domain SAC3_GANP PF03399.16 CAR23141.1 - 2.2e-20 73.3 4.3 1.1e-18 67.7 4.3 2.2 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CAR23141.1 - 1.7e-05 24.8 2.4 0.0001 22.3 1.5 2.5 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CAR23141.1 - 0.015 15.8 0.9 0.14 12.7 0.1 2.9 2 1 1 3 3 3 0 PCI domain Mito_fiss_reg PF05308.11 CAR23141.1 - 0.063 13.4 7.4 0.14 12.2 7.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_C12 PF01088.21 CAR23142.1 - 6.9e-46 156.7 0.0 7.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Rpr2 PF04032.16 CAR23143.1 - 8.5e-12 45.2 0.1 5.8e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 CAR23143.1 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 Double zinc ribbon DUF866 PF05907.13 CAR23143.1 - 0.024 14.5 0.3 0.046 13.6 0.3 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) zf-C2H2_3 PF13878.6 CAR23143.1 - 0.036 13.9 0.2 0.33 10.8 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CpXC PF14353.6 CAR23143.1 - 0.063 13.3 0.7 0.11 12.5 0.7 1.6 1 1 1 2 2 2 0 CpXC protein zf-RRN7 PF11781.8 CAR23143.1 - 0.21 11.3 3.4 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_2 PF13240.6 CAR23143.1 - 0.22 11.3 5.6 0.84 9.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pex24p PF06398.11 CAR23144.1 - 7.6e-79 265.3 2.7 9.3e-79 265.0 2.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PQQ_3 PF13570.6 CAR23145.1 - 3.6e-09 36.8 2.7 0.55 10.8 0.0 4.9 5 0 0 5 5 5 3 PQQ-like domain PQQ_2 PF13360.6 CAR23145.1 - 4.9e-08 32.8 0.3 1.9e-07 30.9 0.2 1.7 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 CAR23145.1 - 0.00019 21.7 0.1 8 6.8 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR23145.1 - 0.00038 21.2 3.1 0.045 14.6 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ PF01011.21 CAR23145.1 - 0.00043 20.1 5.3 0.2 11.7 0.0 4.7 6 0 0 6 6 6 1 PQQ enzyme repeat WD40_like PF17005.5 CAR23145.1 - 0.00053 19.4 0.0 0.22 10.8 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain vATP-synt_E PF01991.18 CAR23145.1 - 0.2 11.0 0.0 3.7 6.9 0.0 2.2 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit SET PF00856.28 CAR23146.1 - 1.1e-18 68.2 0.1 2.1e-18 67.3 0.1 1.5 1 0 0 1 1 1 1 SET domain TPR_1 PF00515.28 CAR23147.1 - 2.3e-42 141.1 25.5 5.6e-07 29.1 0.0 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 CAR23147.1 - 5.5e-34 115.9 19.6 6.3e-17 61.3 2.9 2.8 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 CAR23147.1 - 8e-34 113.0 26.1 8.1e-05 22.4 0.1 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 CAR23147.1 - 2.7e-20 72.4 12.7 1.5e-08 34.8 0.5 6.3 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAR23147.1 - 2.7e-19 67.7 20.5 0.00027 20.9 0.2 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 CAR23147.1 - 1.6e-18 66.1 25.8 0.0006 19.5 0.1 8.4 7 1 1 8 8 8 6 TPR repeat TPR_16 PF13432.6 CAR23147.1 - 2.7e-18 66.3 12.3 0.00011 22.8 0.0 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAR23147.1 - 1.2e-14 53.7 8.9 1.8 9.6 0.0 8.8 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 CAR23147.1 - 4.3e-13 48.3 13.5 5.9e-05 22.8 0.0 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR23147.1 - 6.2e-12 45.9 18.5 0.003 18.0 0.1 7.3 5 3 2 7 7 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 CAR23147.1 - 3.7e-08 33.0 8.1 0.034 14.0 0.1 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAR23147.1 - 5.1e-07 29.6 8.8 1.9 9.0 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR23147.1 - 4e-06 26.9 0.1 0.0045 17.1 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR23147.1 - 3.5e-05 24.0 13.8 0.37 11.1 0.2 4.9 2 2 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CAR23147.1 - 0.0013 19.3 22.1 1.9 9.3 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF3808 PF10300.9 CAR23147.1 - 0.0026 16.6 0.2 0.0026 16.6 0.2 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) PPR PF01535.20 CAR23147.1 - 0.0054 16.9 1.5 73 3.9 0.0 5.8 6 0 0 6 6 6 0 PPR repeat SHNi-TPR PF10516.9 CAR23147.1 - 0.0063 15.9 5.5 13 5.3 0.0 5.8 6 0 0 6 6 6 0 SHNi-TPR Fis1_TPR_C PF14853.6 CAR23147.1 - 0.0069 16.4 5.1 18 5.5 0.1 5.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Rep_Org_C PF06926.11 CAR23147.1 - 0.012 15.9 0.4 7.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Putative replisome organiser protein C-terminus PPR_2 PF13041.6 CAR23147.1 - 0.051 13.8 4.1 19 5.5 0.0 5.1 6 0 0 6 6 5 0 PPR repeat family DS PF01916.17 CAR23147.1 - 0.066 12.4 0.1 0.19 11.0 0.1 1.7 1 0 0 1 1 1 0 Deoxyhypusine synthase Foie-gras_1 PF11817.8 CAR23147.1 - 0.15 11.6 6.1 1.1 8.9 4.0 3.0 1 1 1 2 2 2 0 Foie gras liver health family 1 TPR_20 PF14561.6 CAR23147.1 - 0.53 10.7 9.2 5.3 7.5 0.1 4.4 4 3 0 4 4 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 CAR23147.1 - 2.2 8.1 11.1 0.96 9.2 2.2 3.0 2 1 0 2 2 2 0 XPC-binding domain MIT PF04212.18 CAR23147.1 - 5.4 7.2 21.4 29 4.8 0.1 7.0 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain HemY_N PF07219.13 CAR23147.1 - 8.2 6.7 12.7 6.8 6.9 0.5 4.1 4 0 0 4 4 3 0 HemY protein N-terminus DnaI_N PF07319.11 CAR23147.1 - 8.8 7.1 12.8 37 5.1 0.5 5.2 5 2 1 6 6 6 0 Primosomal protein DnaI N-terminus AAA_2 PF07724.14 CAR23148.1 - 1.7e-52 177.9 0.1 3.7e-50 170.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CAR23148.1 - 1.1e-35 121.6 0.4 1.1e-35 121.6 0.4 2.7 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CAR23148.1 - 2.2e-24 85.3 0.4 2.2e-24 85.3 0.4 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CAR23148.1 - 4.6e-22 78.9 0.1 3.6e-11 43.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR23148.1 - 5.5e-16 58.8 1.8 6.4e-12 45.7 0.0 4.1 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR23148.1 - 4.9e-10 40.0 4.2 0.0003 21.2 0.1 4.0 3 2 1 4 4 3 2 AAA ATPase domain ATPase_2 PF01637.18 CAR23148.1 - 1.9e-07 31.3 3.5 0.16 11.9 0.1 4.2 3 2 0 4 4 4 2 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 CAR23148.1 - 2.3e-07 30.7 0.1 1.3e-05 25.0 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 CAR23148.1 - 3.1e-07 30.0 0.1 0.00014 21.3 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_14 PF13173.6 CAR23148.1 - 7.2e-07 29.3 0.0 0.01 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CAR23148.1 - 9e-07 29.2 0.1 0.12 12.6 0.1 3.2 2 2 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CAR23148.1 - 4.8e-06 26.4 0.0 0.035 13.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 CAR23148.1 - 1.2e-05 24.9 0.1 0.026 14.0 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CAR23148.1 - 1.8e-05 25.3 1.9 0.17 12.5 0.0 3.4 3 1 0 3 3 2 2 AAA domain ABC_tran PF00005.27 CAR23148.1 - 3.4e-05 24.4 0.6 0.1 13.1 0.0 3.4 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CAR23148.1 - 6.2e-05 23.0 0.0 0.034 14.1 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 CAR23148.1 - 0.00019 21.2 0.3 1.3 8.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 CAR23148.1 - 0.00021 21.2 0.0 0.097 12.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain LacI PF00356.21 CAR23148.1 - 0.00032 20.4 0.0 0.097 12.5 0.0 3.6 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family TsaE PF02367.17 CAR23148.1 - 0.00036 20.5 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CAR23148.1 - 0.00036 19.9 0.0 0.0094 15.2 0.0 3.0 2 1 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 CAR23148.1 - 0.00043 20.6 0.1 0.41 10.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 CAR23148.1 - 0.00044 19.9 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 CAR23148.1 - 0.0006 20.0 0.1 1.1 9.5 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_6 PF12774.7 CAR23148.1 - 0.00063 18.8 0.4 0.13 11.2 0.0 3.0 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 CAR23148.1 - 0.0007 19.9 0.0 1.6 9.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase PduV-EutP PF10662.9 CAR23148.1 - 0.00071 19.3 0.0 0.4 10.4 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 CAR23148.1 - 0.00075 18.7 0.8 0.67 9.1 0.2 3.4 2 2 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CAR23148.1 - 0.0014 18.0 0.1 0.83 9.0 0.0 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CAR23148.1 - 0.0024 17.5 0.0 0.12 12.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 CAR23148.1 - 0.0034 17.4 0.1 0.76 9.8 0.0 3.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 CAR23148.1 - 0.0066 16.1 0.0 1.3 8.6 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 CAR23148.1 - 0.012 14.7 0.7 0.082 12.0 0.6 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein Bac_DnaA PF00308.18 CAR23148.1 - 0.012 15.5 0.0 1.9 8.3 0.0 2.8 3 0 0 3 3 2 0 Bacterial dnaA protein AAA_21 PF13304.6 CAR23148.1 - 0.012 15.4 5.6 0.81 9.4 0.1 4.1 2 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Torsin PF06309.11 CAR23148.1 - 0.017 15.2 0.0 0.05 13.7 0.0 1.8 1 0 0 1 1 1 0 Torsin AAA_3 PF07726.11 CAR23148.1 - 0.02 14.7 0.1 0.39 10.6 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAR23148.1 - 0.021 14.6 0.0 5.6 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CAR23148.1 - 0.022 15.1 3.9 4.2 7.7 0.1 4.1 3 2 1 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 CAR23148.1 - 0.024 14.7 0.0 1.8 8.7 0.0 3.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CAR23148.1 - 0.026 14.7 0.0 6.5 6.9 0.0 3.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CAR23148.1 - 0.034 13.9 0.1 8.2 6.1 0.0 3.5 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain DUF87 PF01935.17 CAR23148.1 - 0.039 14.0 3.5 1.1 9.4 0.0 3.4 3 0 0 3 3 3 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 CAR23148.1 - 0.044 13.6 0.0 7.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PhoH PF02562.16 CAR23148.1 - 0.05 13.1 0.0 3.2 7.2 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.15 CAR23148.1 - 0.051 13.5 0.1 22 4.9 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA_23 PF13476.6 CAR23148.1 - 0.19 12.2 17.6 11 6.5 0.3 3.7 2 2 0 2 2 2 0 AAA domain bZIP_1 PF00170.21 CAR23149.1 - 8.2e-09 35.4 11.3 2.1e-08 34.1 11.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor TMCO5 PF14992.6 CAR23149.1 - 0.07 12.7 0.2 0.07 12.7 0.2 1.5 2 0 0 2 2 2 0 TMCO5 family Sporozoite_P67 PF05642.11 CAR23149.1 - 0.11 10.6 4.4 0.14 10.2 4.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PRKG1_interact PF15898.5 CAR23149.1 - 1.4 9.9 10.0 0.12 13.3 3.0 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4666 PF15697.5 CAR23149.1 - 2.1 9.0 5.8 0.54 11.0 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4666) bZIP_Maf PF03131.17 CAR23149.1 - 2.3 8.8 19.6 0.11 13.0 6.2 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Ribosomal_60s PF00428.19 CAR23149.1 - 6.4 7.4 8.9 3.7 8.2 3.3 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Apc13p PF05839.11 CAR23150.1 - 0.00039 20.6 0.3 0.00079 19.6 0.3 1.5 1 0 0 1 1 1 1 Apc13p protein PalH PF08733.10 CAR23151.1 - 1.3e-89 300.5 16.0 1.5e-89 300.3 16.0 1.0 1 0 0 1 1 1 1 PalH/RIM21 CBM_5_12_2 PF14600.6 CAR23151.1 - 0.0086 16.0 0.5 0.037 14.0 0.1 2.2 2 0 0 2 2 2 1 Cellulose-binding domain Fasciclin PF02469.22 CAR23152.1 - 0.0023 18.1 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain HUN PF08729.10 CAR23152.1 - 0.24 11.4 0.9 19 5.3 0.0 2.9 3 0 0 3 3 3 0 HPC2 and ubinuclein domain HLH PF00010.26 CAR23153.1 - 3.4e-18 65.4 0.9 7.2e-18 64.3 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2247 PF10004.9 CAR23153.1 - 0.21 11.4 1.5 0.51 10.1 1.5 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) XPG_N PF00752.17 CAR23154.1 - 3.4e-25 88.4 0.0 7e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CAR23154.1 - 3.5e-20 72.1 0.0 1.2e-19 70.5 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CAR23154.1 - 8e-05 23.2 0.0 0.00041 20.9 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.7 CAR23154.1 - 0.0023 17.5 0.0 0.0072 15.8 0.0 1.8 1 1 1 2 2 2 1 XPG domain containing HHH_2 PF12826.7 CAR23154.1 - 0.0048 17.0 0.1 0.15 12.2 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif TPR_2 PF07719.17 CAR23154.1 - 0.053 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat CppA_N PF14506.6 CAR23154.1 - 0.069 13.2 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 CppA N-terminal TPR_8 PF13181.6 CAR23154.1 - 0.1 12.9 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR23154.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.7 CAR23155.1 - 1.4e-31 108.9 0.0 9.2e-11 42.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) DHHC PF01529.20 CAR23155.1 - 2e-22 79.7 5.5 2e-22 79.7 5.5 2.6 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 CAR23155.1 - 7.8e-20 71.0 0.1 1.5e-06 28.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR23155.1 - 1.4e-18 66.7 0.3 2.4e-05 24.5 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR23155.1 - 1.9e-18 64.6 0.0 0.0018 18.6 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CAR23155.1 - 3.6e-17 62.0 0.0 2.5e-05 24.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat UNC45-central PF11701.8 CAR23156.1 - 4.6e-24 85.1 2.2 1.7e-23 83.3 2.2 2.0 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central M16C_assoc PF08367.11 CAR23156.1 - 0.015 14.5 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase M16C associated CwsA PF10814.8 CAR23156.1 - 0.066 13.4 1.8 0.85 9.8 0.2 2.5 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Pex2_Pex12 PF04757.14 CAR23157.1 - 5.3e-33 114.5 3.8 6.8e-33 114.1 3.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CAR23157.1 - 6.1e-09 35.6 12.4 9.2e-09 35.0 12.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR23157.1 - 3.4e-08 33.7 12.7 5.6e-08 33.0 12.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAR23157.1 - 3.6e-08 33.2 10.4 6.7e-08 32.3 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR23157.1 - 4e-07 29.8 12.3 7e-07 29.0 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR23157.1 - 2.3e-06 27.4 12.9 3.8e-06 26.7 12.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CAR23157.1 - 2.3e-06 27.5 6.7 2.3e-06 27.5 6.7 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAR23157.1 - 0.00013 21.9 7.4 0.00029 20.7 7.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CAR23157.1 - 0.00022 21.5 8.9 0.00053 20.2 8.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CAR23157.1 - 0.0013 18.8 13.0 0.0025 17.9 13.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CAR23157.1 - 0.057 13.5 4.0 0.1 12.7 4.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 CAR23157.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-RING_10 PF16685.5 CAR23157.1 - 0.7 10.1 11.8 1.4 9.1 11.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 CAR23157.1 - 1.1 9.5 10.5 3.3 8.0 10.4 1.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 CAR23157.1 - 6.4 6.7 12.6 12 5.8 12.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CAR23158.1 - 8.2e-09 35.2 8.5 8.2e-09 35.2 8.5 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR23158.1 - 0.00019 21.2 7.0 0.00019 21.2 7.0 3.1 4 1 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CAR23158.1 - 0.00023 20.9 7.8 0.00023 20.9 7.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR23158.1 - 0.0064 16.3 10.8 0.0064 16.3 10.8 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR23158.1 - 0.016 15.5 9.0 0.016 15.5 9.0 3.3 3 1 1 4 4 4 0 Ring finger domain zf-Di19 PF05605.12 CAR23158.1 - 0.89 9.9 16.3 0.68 10.3 0.2 4.4 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 CAR23158.1 - 1 9.4 10.0 0.31 11.1 5.5 2.6 2 0 0 2 2 2 0 RING-type zinc-finger PGP_phosphatase PF09419.10 CAR23159.1 - 6.9e-67 224.2 0.0 7.9e-67 224.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CAR23159.1 - 8.7e-07 28.9 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like FAT PF02259.23 CAR23160.1 - 2.5e-71 240.7 9.8 2.5e-71 240.7 9.8 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CAR23160.1 - 1.6e-49 169.0 3.3 1.9e-49 168.8 0.4 2.7 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CAR23160.1 - 3.5e-05 23.5 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 FATC domain PXA PF02194.15 CAR23160.1 - 0.0088 16.0 5.9 0.24 11.4 0.1 3.9 3 0 0 3 3 3 2 PXA domain Sec23_helical PF04815.15 CAR23160.1 - 0.015 15.1 0.4 0.17 11.8 0.1 2.8 2 0 0 2 2 2 0 Sec23/Sec24 helical domain AATF-Che1 PF13339.6 CAR23160.1 - 0.62 10.8 4.7 4.6 7.9 4.7 2.6 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Sugar_tr PF00083.24 CAR23161.1 - 7.3e-60 203.1 27.4 1.6e-59 201.9 27.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR23161.1 - 2.5e-18 66.1 31.2 2.5e-18 66.1 31.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DMT_YdcZ PF04657.13 CAR23161.1 - 0.15 12.3 16.8 0.19 12.0 4.1 3.6 3 0 0 3 3 3 0 Putative inner membrane exporter, YdcZ Asp PF00026.23 CAR23162.1 - 3.4e-30 105.5 0.8 1.5e-29 103.5 0.8 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR23162.1 - 0.0022 18.3 0.2 0.0022 18.3 0.2 2.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Sec23_trunk PF04811.15 CAR23163.1 - 2.2e-55 187.9 0.5 5.1e-55 186.7 0.1 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CAR23163.1 - 1.7e-15 56.7 1.5 2.2e-15 56.3 0.3 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CAR23163.1 - 3.8e-13 50.0 0.0 8.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CAR23163.1 - 5.7e-10 39.1 4.1 1.2e-09 38.0 2.5 2.3 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CAR23163.1 - 0.00045 20.1 0.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat UPF0047 PF01894.17 CAR23163.1 - 0.0043 17.2 0.2 0.17 12.1 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein family UPF0047 Pal1 PF08316.11 CAR23165.1 - 9.9e-51 172.1 2.3 9.9e-51 172.1 2.3 2.8 2 1 1 3 3 3 1 Pal1 cell morphology protein Bul1_N PF04425.12 CAR23165.1 - 0.015 14.0 3.3 0.023 13.5 3.3 1.2 1 0 0 1 1 1 0 Bul1 N terminus DUF913 PF06025.12 CAR23165.1 - 0.1 11.6 0.7 0.2 10.6 0.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CAR23165.1 - 0.46 9.2 5.5 0.7 8.6 5.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CAR23165.1 - 0.75 8.5 4.4 1.3 7.7 4.4 1.3 1 0 0 1 1 1 0 Presenilin CiPC PF15800.5 CAR23165.1 - 6.2 6.4 19.2 0.25 11.0 12.5 1.8 2 0 0 2 2 2 0 Clock interacting protein circadian Sod_Fe_C PF02777.18 CAR23166.1 - 4.7e-11 42.8 0.2 0.00014 22.0 0.1 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Svf1 PF08622.10 CAR23167.1 - 1e-63 214.2 0.1 1.5e-63 213.7 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CAR23167.1 - 2.4e-63 212.9 0.9 3.2e-63 212.5 0.1 1.6 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Sugar_tr PF00083.24 CAR23168.1 - 3.2e-165 550.4 31.8 3.7e-165 550.2 31.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR23168.1 - 9.5e-32 110.3 40.4 6.3e-30 104.3 22.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CAR23168.1 - 0.024 13.1 2.5 0.041 12.3 2.5 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DUF5134 PF17197.4 CAR23168.1 - 0.12 12.3 0.2 0.29 11.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) Sugar_tr PF00083.24 CAR23169.1 - 4.6e-171 569.6 33.5 5.3e-171 569.4 33.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR23169.1 - 3.9e-29 101.7 30.6 3.3e-26 92.1 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 CAR23169.1 - 0.015 14.9 6.2 0.026 14.1 0.4 3.1 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 tRNA-synt_1d PF00750.19 CAR23171.1 - 2e-116 388.7 3.8 2.5e-116 388.4 3.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CAR23171.1 - 2.8e-30 105.0 0.7 6.6e-29 100.5 0.3 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CAR23171.1 - 3.6e-08 33.9 0.0 1.3e-07 32.1 0.0 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain RVT_2 PF07727.14 CAR23171.1 - 0.0082 15.8 1.0 0.52 9.9 1.2 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Fcf1 PF04900.12 CAR23172.1 - 9.7e-35 118.9 0.2 1.6e-34 118.2 0.2 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CAR23172.1 - 7.1e-14 52.1 0.2 1.2e-13 51.3 0.0 1.4 2 0 0 2 2 2 1 PIN like domain Imm-NTF2 PF15655.6 CAR23172.1 - 0.035 14.4 0.0 0.086 13.1 0.0 1.6 2 0 0 2 2 2 0 NTF2 fold immunity protein DUF4112 PF13430.6 CAR23173.1 - 4.2e-33 113.7 0.1 5.5e-33 113.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) ING PF12998.7 CAR23174.1 - 2.8e-21 76.0 1.8 3.9e-21 75.5 1.8 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CAR23174.1 - 9.5e-07 28.6 8.5 1.9e-06 27.6 8.5 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CAR23174.1 - 0.00042 20.5 1.1 0.00068 19.8 0.2 1.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain MIP-T3_C PF17749.1 CAR23174.1 - 0.062 13.3 0.9 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region zf-RING_2 PF13639.6 CAR23174.1 - 1.3 9.4 5.7 2.6 8.5 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain MatE PF01554.18 CAR23175.1 - 7.2e-61 204.5 33.9 7.6e-39 132.9 8.1 2.6 3 0 0 3 3 3 2 MatE Abhydrolase_1 PF00561.20 CAR23176.1 - 1.8e-40 139.3 0.0 4.8e-40 137.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CAR23176.1 - 0.0069 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CAR23176.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR23176.1 - 0.017 15.7 0.1 0.028 15.0 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_S15 PF00312.22 CAR23177.1 - 2.7e-30 104.4 1.2 2.7e-30 104.4 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 INTS5_C PF14838.6 CAR23177.1 - 0.033 12.8 0.3 0.047 12.3 0.3 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus SAM_DrpA PF18255.1 CAR23177.1 - 0.037 14.3 0.3 1.5 9.2 0.1 2.9 2 1 0 2 2 2 0 DNA processing protein A sterile alpha motif domain DUF3487 PF11990.8 CAR23177.1 - 0.045 13.6 0.1 0.097 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) ResIII PF04851.15 CAR23178.1 - 0.0035 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAR23178.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HSR PF03172.13 CAR23178.1 - 0.11 12.7 0.1 0.91 9.7 0.1 2.6 2 0 0 2 2 2 0 HSR domain Gar1 PF04410.14 CAR23179.1 - 6.7e-40 136.4 0.0 8.1e-40 136.1 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region MMR_HSR1 PF01926.23 CAR23180.1 - 2.6e-18 66.2 0.0 3.9e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR23180.1 - 6.6e-07 29.4 0.1 7.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CAR23180.1 - 9e-07 28.6 0.1 6.2e-06 25.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAR23180.1 - 3.1e-06 27.3 0.0 0.16 12.0 0.0 2.9 2 1 1 3 3 3 2 Dynamin family FeoB_N PF02421.18 CAR23180.1 - 7.6e-05 22.3 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CAR23180.1 - 0.002 17.5 0.1 0.0034 16.7 0.1 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 CAR23180.1 - 0.0038 16.7 0.0 0.018 14.5 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CAR23180.1 - 0.03 14.1 0.2 11 5.7 0.4 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CAR23180.1 - 0.039 14.5 0.4 0.23 12.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Abhydrolase_3 PF07859.13 CAR23182.1 - 6.7e-61 205.8 0.1 8.4e-61 205.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CAR23182.1 - 2.6e-09 36.5 0.0 7.5e-09 35.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CAR23182.1 - 0.00035 20.1 0.1 0.0027 17.2 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CAR23182.1 - 0.0059 15.5 0.0 0.0097 14.8 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase D-ser_dehydrat PF14031.6 CAR23183.1 - 3.5e-23 82.1 0.0 7.4e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CAR23183.1 - 9.2e-13 48.3 0.0 1.2e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fungal_trans PF04082.18 CAR23184.1 - 5e-57 193.0 3.1 5e-57 193.0 3.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CAR23184.1 - 0.0037 17.6 8.6 0.012 16.1 2.3 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 CAR23184.1 - 0.02 15.5 3.3 0.42 11.3 0.7 2.7 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CAR23184.1 - 0.54 11.2 17.6 0.057 14.3 1.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.16 CAR23185.1 - 3.3e-32 111.8 20.0 3.6e-32 111.7 15.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR23185.1 - 4.4e-05 22.5 19.4 0.00026 20.0 18.3 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Herpes_gE PF02480.16 CAR23185.1 - 0.052 12.3 0.0 0.1 11.3 0.0 1.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Ribonuc_L-PSP PF01042.21 CAR23186.1 - 7.2e-22 77.7 0.3 9e-22 77.4 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_M20 PF01546.28 CAR23187.1 - 2.8e-30 105.6 0.1 4e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 CAR23187.1 - 1.6e-07 31.2 0.0 2.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 CAR23187.1 - 1.3e-06 28.3 0.0 2.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 CAR23188.1 - 1e-39 136.5 21.4 3.8e-39 134.6 21.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Colicin_V PF02674.16 CAR23188.1 - 0.15 12.0 0.0 0.15 12.0 0.0 3.5 3 1 1 4 4 4 0 Colicin V production protein CRA PF06589.11 CAR23188.1 - 0.18 11.9 1.9 0.27 11.4 0.2 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DUF443 PF04276.12 CAR23188.1 - 2.2 8.0 5.4 2.1 8.1 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF443) CPP1-like PF11833.8 CAR23188.1 - 5.8 6.5 12.2 6.6 6.3 5.3 2.7 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Fungal_trans PF04082.18 CAR23189.1 - 2e-22 79.5 0.2 3.8e-22 78.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23189.1 - 0.00027 21.0 10.3 0.00075 19.6 10.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldolase_II PF00596.21 CAR23190.1 - 4.9e-42 144.0 0.1 6.1e-42 143.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Peptidase_M20 PF01546.28 CAR23191.1 - 7.9e-34 117.2 0.0 1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 CAR23191.1 - 5.4e-05 23.0 0.0 8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 M20_dimer PF07687.14 CAR23191.1 - 0.00081 19.3 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Wzy_C_2 PF11846.8 CAR23192.1 - 0.019 14.9 0.8 0.028 14.3 0.8 1.2 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DUF2259 PF10016.9 CAR23192.1 - 0.45 10.4 2.6 0.46 10.4 1.2 1.6 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) IFP_35_N PF07334.13 CAR23192.1 - 0.84 9.8 11.0 3.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BNIP2 PF12496.8 CAR23192.1 - 1 9.8 6.6 4.7 7.7 6.5 2.0 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 C2-set PF05790.15 CAR23192.1 - 1.3 9.3 5.4 6.7 7.0 3.0 2.5 2 0 0 2 2 2 0 Immunoglobulin C2-set domain UPF0242 PF06785.11 CAR23192.1 - 1.8 8.7 15.9 5.1 7.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF743 PF05332.11 CAR23192.1 - 6.7 6.8 8.2 1.4 9.0 3.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF743) Brix PF04427.18 CAR23193.1 - 1.3e-26 93.9 0.8 2.3e-26 93.1 0.8 1.4 1 0 0 1 1 1 1 Brix domain DUF1764 PF08576.10 CAR23193.1 - 0.38 11.7 5.4 0.9 10.5 5.4 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RhoGEF PF00621.20 CAR23194.1 - 5.6e-15 56.0 3.2 7.2e-15 55.7 2.5 1.6 2 0 0 2 2 2 1 RhoGEF domain SBDS PF01172.18 CAR23195.1 - 1.1e-14 54.3 0.2 1.2e-14 54.1 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNF2_N PF00176.23 CAR23196.1 - 6.6e-67 225.7 0.2 1.3e-66 224.7 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR23196.1 - 5.7e-18 65.3 0.0 3.8e-17 62.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 CAR23196.1 - 4.4e-16 59.0 10.2 4.4e-16 59.0 10.2 2.9 1 1 1 2 2 2 1 HSA ResIII PF04851.15 CAR23196.1 - 1.1e-11 45.0 0.0 1.1e-11 45.0 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR23196.1 - 1.2e-06 28.4 0.0 1.2e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 CAR23196.1 - 0.088 12.4 1.5 0.28 10.8 0.0 2.6 3 0 0 3 3 3 0 DEAD_2 DUF2315 PF10231.9 CAR23196.1 - 6.8 6.8 8.4 6.3 6.9 0.7 2.9 2 0 0 2 2 2 0 Apoptogenic protein 1 RRM_1 PF00076.22 CAR23197.1 - 6.3e-44 147.7 0.0 2.3e-16 59.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR23197.1 - 1.4e-05 24.7 0.1 0.19 11.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR23197.1 - 0.0003 20.8 0.1 0.11 12.6 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 CAR23197.1 - 0.0019 18.0 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CAR23197.1 - 0.0041 17.1 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF2852 PF11014.8 CAR23197.1 - 0.024 14.8 0.1 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) RRM_3 PF08777.11 CAR23197.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Ipi1_N PF12333.8 CAR23198.1 - 1.8e-25 89.5 0.4 1.8e-25 89.5 0.4 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 CAR23198.1 - 0.12 12.7 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat Tcf25 PF04910.14 CAR23199.1 - 2.3e-77 260.4 0.8 3.3e-77 259.9 0.8 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF2628 PF10947.8 CAR23199.1 - 0.16 12.4 0.3 0.31 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Stm1_N PF09598.10 CAR23199.1 - 0.39 11.6 12.3 0.15 12.9 9.3 1.9 1 1 1 2 2 2 0 Stm1 STE PF02200.16 CAR23200.1 - 1.3e-58 196.2 2.7 1.9e-58 195.6 2.7 1.2 1 0 0 1 1 1 1 STE like transcription factor DAGK_cat PF00781.24 CAR23200.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain SAM35 PF10806.8 CAR23201.1 - 9.5e-46 155.2 0.1 1.3e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_6 PF17171.4 CAR23201.1 - 0.0048 16.7 0.2 0.015 15.1 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain ESSS PF10183.9 CAR23201.1 - 0.055 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ResIII PF04851.15 CAR23202.1 - 1.9e-27 96.4 0.0 9.1e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR23202.1 - 4.6e-16 59.1 0.0 1.1e-15 57.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR23202.1 - 9.1e-16 58.2 1.3 8.4e-13 48.6 0.1 3.5 3 1 1 4 4 4 2 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 CAR23202.1 - 6.8e-06 25.9 0.1 2.4e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CAR23202.1 - 0.00061 20.1 0.2 0.0061 16.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CAR23202.1 - 0.001 18.4 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ERCC3_RAD25_C PF16203.5 CAR23202.1 - 0.0046 16.2 0.0 0.0098 15.1 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 CAR23202.1 - 0.027 14.2 0.0 0.079 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CAR23203.1 - 2.4e-44 151.7 1.3 2e-40 138.9 0.2 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23203.1 - 1.3e-21 77.1 0.2 1.6e-20 73.5 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR23203.1 - 0.00014 21.3 0.0 0.00027 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CAR23203.1 - 0.00089 18.9 0.9 0.01 15.5 0.9 2.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CAR23203.1 - 0.015 14.9 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Peptidase_C13 PF01650.18 CAR23204.1 - 1.5e-47 162.3 1.4 2.5e-47 161.5 1.4 1.3 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 CAR23204.1 - 0.049 13.9 0.0 0.21 11.9 0.0 2.0 1 0 0 1 1 1 0 Mid domain of argonaute Thioredoxin_7 PF13899.6 CAR23205.1 - 4.1e-21 75.0 0.1 6.8e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 CAR23205.1 - 3e-15 56.2 0.6 9.2e-14 51.4 0.0 2.5 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 CAR23205.1 - 4.9e-13 48.7 0.3 9.9e-13 47.7 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain UIM PF02809.20 CAR23205.1 - 1.7 8.7 4.5 3 8.0 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif Sas10_Utp3 PF04000.15 CAR23206.1 - 3.2e-06 27.7 1.0 3.2e-06 27.7 1.0 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Pyrophosphatase PF00719.19 CAR23206.1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Inorganic pyrophosphatase S_4TM PF18159.1 CAR23206.1 - 0.085 12.1 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain ISG65-75 PF11727.8 CAR23206.1 - 0.18 11.0 3.8 0.045 13.0 0.8 1.5 2 0 0 2 2 2 0 Invariant surface glycoprotein Peroxin-3 PF04882.12 CAR23208.1 - 6.7e-110 368.3 19.8 1.3e-109 367.3 19.8 1.4 1 1 0 1 1 1 1 Peroxin-3 DUF758 PF05527.11 CAR23208.1 - 0.12 12.4 7.5 0.023 14.7 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF758) Skp1 PF01466.19 CAR23209.1 - 8.1e-25 86.7 0.2 8.1e-25 86.7 0.2 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CAR23209.1 - 2.2e-14 53.3 0.0 8.3e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Tic110 PF16940.5 CAR23209.1 - 0.13 10.8 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter DNA_pol_phi PF04931.13 CAR23209.1 - 9.4 4.2 8.3 12 3.8 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi VASt PF16016.5 CAR23210.1 - 2.6e-73 245.5 0.6 4.8e-36 124.5 0.0 3.2 3 0 0 3 3 3 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CAR23210.1 - 1.1e-28 99.4 0.1 2.1e-28 98.5 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Pkinase PF00069.25 CAR23211.1 - 7.3e-41 140.3 0.0 2.1e-39 135.5 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 CAR23211.1 - 4.5e-40 136.7 0.0 9.6e-40 135.7 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CAR23211.1 - 2.2e-25 89.4 0.0 3.7e-24 85.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 CAR23211.1 - 0.00044 20.0 0.2 5.6 7.1 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.14 CAR23211.1 - 0.0059 16.0 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CAR23211.1 - 0.011 14.6 1.3 0.014 14.2 0.3 1.7 2 0 0 2 2 2 0 Fungal protein kinase PQQ_2 PF13360.6 CAR23211.1 - 0.014 15.0 0.0 0.049 13.2 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain GEMIN8 PF15348.6 CAR23211.1 - 0.38 11.0 3.6 0.79 10.0 3.6 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Cnd3 PF12719.7 CAR23212.1 - 2.3e-89 299.5 2.9 2.3e-89 299.5 2.9 1.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CAR23212.1 - 3e-06 27.0 0.8 1.4 9.4 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CAR23212.1 - 4.6e-06 26.9 0.2 0.029 14.8 0.1 4.5 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CAR23212.1 - 0.0019 18.3 5.5 0.061 13.4 0.3 4.3 4 2 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 PF12894.7 CAR23213.1 - 1.9e-08 34.5 5.5 0.017 15.4 0.2 5.8 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR23213.1 - 1.6e-05 25.5 17.5 3.4 8.7 0.1 8.8 10 0 0 10 10 10 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CAR23213.1 - 0.02 13.7 1.5 0.21 10.3 0.3 2.3 1 1 1 2 2 2 0 Nup133 N terminal like GP67 PF17634.2 CAR23213.1 - 3 8.3 12.6 2 8.9 8.9 2.3 2 0 0 2 2 2 0 Gene product 67 ABA_GPCR PF12430.8 CAR23214.1 - 3.2e-57 193.2 3.0 3.2e-57 193.2 3.0 2.1 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CAR23214.1 - 2.2e-16 59.7 0.2 1e-15 57.5 0.0 2.2 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal ECF_trnsprt PF12822.7 CAR23214.1 - 0.0035 17.5 3.6 0.017 15.2 3.6 2.3 1 1 0 1 1 1 1 ECF transporter, substrate-specific component SpoIIIAC PF06686.11 CAR23214.1 - 0.14 12.4 1.6 0.29 11.3 0.1 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family Wzy_C_2 PF11846.8 CAR23214.1 - 0.26 11.2 1.4 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal DUF1622 PF07784.11 CAR23214.1 - 0.56 10.2 2.7 6.5 6.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1622) DUF1129 PF06570.11 CAR23214.1 - 9.6 5.6 11.9 2.7 7.4 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1129) FYVE PF01363.21 CAR23215.1 - 1.3e-21 76.5 27.4 2.1e-17 63.0 3.1 2.8 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 CAR23215.1 - 4e-17 61.6 2.0 4e-17 61.6 2.0 2.3 2 0 0 2 2 2 1 Rabenosyn Rab binding domain DUF2396 PF09654.10 CAR23215.1 - 0.0053 16.9 1.0 0.47 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2396) Ribosomal_L12 PF00542.19 CAR23215.1 - 0.021 15.2 0.2 0.16 12.4 0.3 2.2 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain HypA PF01155.19 CAR23215.1 - 0.033 14.2 14.3 0.18 11.8 2.9 3.3 2 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-AN1 PF01428.16 CAR23215.1 - 7.1 6.9 25.6 0.39 10.9 8.5 3.4 3 1 1 4 4 4 0 AN1-like Zinc finger Upf2 PF04050.14 CAR23216.1 - 3.5e-30 105.5 6.8 3.5e-30 105.5 6.8 3.2 2 1 1 3 3 3 1 Up-frameshift suppressor 2 MIF4G PF02854.19 CAR23216.1 - 3.1e-26 92.3 37.2 4.9e-16 59.0 4.1 4.1 4 0 0 4 4 4 3 MIF4G domain BUD22 PF09073.10 CAR23216.1 - 6.4e-05 22.5 32.0 0.00016 21.2 32.0 1.7 1 0 0 1 1 1 1 BUD22 SpoIIE PF07228.12 CAR23217.1 - 6.3e-35 120.8 0.0 8.2e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CAR23217.1 - 1.1e-05 25.1 0.1 2.4e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CAR23217.1 - 4.2e-05 23.3 0.1 0.015 15.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PPC PF04151.15 CAR23217.1 - 0.075 14.1 1.1 0.22 12.6 1.1 1.8 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain ATP-synt_E PF05680.12 CAR23218.1 - 2.4e-19 69.5 1.4 2.6e-19 69.4 1.4 1.0 1 0 0 1 1 1 1 ATP synthase E chain JHY PF15261.6 CAR23218.1 - 0.009 16.7 0.7 0.011 16.4 0.7 1.1 1 0 0 1 1 1 1 Jhy protein DivIC PF04977.15 CAR23218.1 - 0.035 13.9 1.9 0.047 13.5 1.9 1.2 1 0 0 1 1 1 0 Septum formation initiator PBP PF01161.20 CAR23219.1 - 1.8e-07 31.5 0.1 2.9e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF4034 PF13226.6 CAR23219.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) Peptidase_M1 PF01433.20 CAR23220.1 - 2.3e-68 230.0 0.0 3.9e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CAR23220.1 - 8.4e-48 163.0 0.8 1.8e-47 161.9 0.4 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CAR23220.1 - 5.6e-40 137.8 0.2 9.2e-40 137.1 0.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain TMEM220 PF15071.6 CAR23220.1 - 0.047 14.4 0.0 0.26 12.0 0.0 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix Glyco_hydro_76 PF03663.14 CAR23221.1 - 7.6e-152 506.1 16.2 8.8e-152 505.8 16.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CAR23221.1 - 0.015 14.4 7.2 0.47 9.5 0.3 3.0 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 ChAPs PF09295.10 CAR23222.1 - 3.6e-153 510.2 0.0 4.6e-153 509.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CAR23222.1 - 0.00091 19.2 5.8 0.014 15.4 0.8 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR23222.1 - 0.0033 17.5 0.5 5.1 7.6 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR23222.1 - 0.034 14.6 3.5 6.9 7.3 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR23222.1 - 0.33 11.2 6.0 6 7.2 0.2 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CAR23222.1 - 0.37 11.7 11.6 7.5 7.7 1.3 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR23222.1 - 1.2 9.8 13.7 0.64 10.7 1.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIID-31kDa PF02291.15 CAR23223.1 - 2.1e-47 160.2 0.1 2.4e-47 160.0 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit MBF1 PF08523.10 CAR23224.1 - 6.3e-24 84.2 1.9 1.3e-23 83.2 0.5 2.0 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CAR23224.1 - 5.1e-14 52.1 0.6 9.3e-14 51.2 0.3 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 CAR23224.1 - 3.1e-06 27.4 0.0 7.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CAR23224.1 - 2.1e-05 24.4 0.2 3.6e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_4 PF12799.7 CAR23225.1 - 8.9e-06 26.0 16.3 1.1 9.7 3.7 7.2 3 2 4 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAR23225.1 - 0.0001 22.1 6.2 5 7.4 0.0 7.3 9 0 0 9 9 9 1 Leucine Rich repeat LRR_1 PF00560.33 CAR23225.1 - 0.00042 20.5 1.6 1.9e+02 3.3 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 CAR23225.1 - 0.0063 16.3 12.9 1.7 8.5 0.0 5.9 5 2 0 5 5 5 2 Leucine rich repeat Allexi_40kDa PF05549.11 CAR23225.1 - 0.084 12.4 1.0 0.14 11.7 1.0 1.4 1 0 0 1 1 1 0 Allexivirus 40kDa protein Acyltransf_C PF16076.5 CAR23226.1 - 0.00028 20.9 0.2 0.00066 19.7 0.2 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CAR23226.1 - 0.00095 18.8 0.0 0.0027 17.3 0.0 1.7 1 1 0 1 1 1 1 Acyltransferase CybS PF05328.12 CAR23227.1 - 9.2e-53 177.5 0.0 1.1e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 CAR23227.1 - 0.0071 16.4 0.7 0.31 11.1 0.7 2.2 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Cauli_VI PF01693.16 CAR23228.1 - 6.7e-32 109.5 1.9 8.1e-20 70.9 0.2 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 CAR23228.1 - 3.9e-30 104.9 0.1 6.4e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 RNase H Macin PF14865.6 CAR23228.1 - 2.8 8.6 4.7 4.9 7.8 0.0 3.1 4 1 0 4 4 4 0 Macin Membr_traf_MHD PF10540.9 CAR23229.1 - 2.5e-44 151.1 0.1 1.3e-43 148.7 0.1 2.3 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 CAR23229.1 - 2.1e-08 33.2 0.2 4.8e-08 32.0 0.2 1.6 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) C2 PF00168.30 CAR23229.1 - 2.6e-06 27.6 0.1 7.2e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain DUF1041 PF06292.17 CAR23229.1 - 0.06 13.8 0.0 0.35 11.3 0.0 2.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) RNase_3_N PF18497.1 CAR23229.1 - 1 9.6 4.7 0.81 10.0 0.1 3.1 3 0 0 3 3 3 0 Ribonuclease III N-terminal domain SWIB PF02201.18 CAR23230.1 - 1.4e-27 95.4 0.8 3.3e-27 94.2 0.8 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 CAR23230.1 - 1.6e-10 40.7 0.4 2e-09 37.3 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain Sas10 PF09368.10 CAR23230.1 - 0.027 14.9 5.1 0.06 13.8 5.1 1.6 1 0 0 1 1 1 0 Sas10 C-terminal domain STAT_alpha PF01017.20 CAR23230.1 - 0.12 12.3 8.9 0.6 10.0 8.7 2.1 1 1 0 1 1 1 0 STAT protein, all-alpha domain ING PF12998.7 CAR23230.1 - 9.8 6.8 10.6 7.5 7.2 5.4 2.9 2 2 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding RRS1 PF04939.12 CAR23231.1 - 2.3e-58 196.7 4.3 2.7e-58 196.4 4.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) VPS11_C PF12451.8 CAR23233.1 - 3.1e-11 43.3 1.6 7.6e-11 42.1 0.5 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CAR23233.1 - 1.1e-07 31.8 4.4 3e-07 30.4 4.4 1.8 1 0 0 1 1 1 1 Zinc-finger zf-RING_UBOX PF13445.6 CAR23233.1 - 1.2e-06 28.5 3.4 3.3e-06 27.0 3.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR23233.1 - 1e-05 25.2 5.5 2.8e-05 23.9 5.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR23233.1 - 0.00013 22.2 6.2 0.00032 21.0 6.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CAR23233.1 - 0.00042 20.2 7.0 0.00042 20.2 7.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CAR23233.1 - 0.002 17.7 3.2 0.0047 16.5 3.2 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 CAR23233.1 - 0.0025 17.6 7.0 0.0077 16.1 7.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CAR23233.1 - 0.0037 17.1 4.6 0.0037 17.1 4.6 2.3 2 0 0 2 2 1 1 PHD-finger zf-ANAPC11 PF12861.7 CAR23233.1 - 0.017 15.1 0.7 0.041 13.9 0.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CAR23233.1 - 0.031 14.6 3.8 0.074 13.3 3.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CAR23233.1 - 0.086 12.6 3.6 0.24 11.2 3.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 CAR23233.1 - 0.38 10.6 4.7 1.7 8.6 4.7 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CAR23233.1 - 8.3 6.5 9.8 0.76 9.8 5.1 1.7 2 0 0 2 2 1 0 Double zinc ribbon Pkinase PF00069.25 CAR23234.1 - 1.9e-66 224.2 0.2 1.6e-59 201.4 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23234.1 - 6.6e-50 169.8 0.1 3.4e-48 164.2 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CAR23234.1 - 1.4e-34 118.4 2.6 4e-34 116.9 0.2 2.7 3 0 0 3 3 3 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CAR23234.1 - 2.8e-10 40.2 1.2 7e-10 38.9 0.1 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CAR23234.1 - 8.8e-10 38.9 0.1 3.5e-09 37.0 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 CAR23234.1 - 0.00036 20.0 0.0 0.0038 16.6 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAR23234.1 - 0.0004 19.3 0.1 0.00093 18.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase SAM_4 PF18017.1 CAR23234.1 - 0.012 15.6 0.1 0.053 13.5 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) VPS38 PF17649.1 CAR23235.1 - 9.5e-115 383.9 4.3 1.1e-114 383.7 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Atg14 PF10186.9 CAR23235.1 - 0.0018 17.4 6.1 0.024 13.7 6.1 2.1 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 CAR23235.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Apg6 BARA domain Zip PF02535.22 CAR23236.1 - 6.3e-46 157.1 18.4 4.5e-41 141.2 6.6 3.0 3 0 0 3 3 3 2 ZIP Zinc transporter DUF2975 PF11188.8 CAR23236.1 - 0.1 12.5 1.0 0.39 10.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF5134 PF17197.4 CAR23236.1 - 2 8.3 5.7 1.4 8.8 2.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5134) MFS_1 PF07690.16 CAR23237.1 - 2e-28 99.4 54.5 4.6e-25 88.3 31.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR23237.1 - 0.00086 18.3 39.3 0.0019 17.2 15.3 3.4 2 2 1 3 3 3 3 Sugar (and other) transporter DUF2684 PF10885.8 CAR23237.1 - 0.053 13.7 2.2 0.18 12.0 2.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2684) AMPK1_CBM PF16561.5 CAR23238.1 - 2.2e-09 37.4 0.8 4e-09 36.6 0.8 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 CAR23238.1 - 0.0045 17.3 0.1 0.0086 16.4 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) CBM53 PF16760.5 CAR23238.1 - 0.011 16.3 1.7 0.02 15.5 0.4 2.0 1 1 1 2 2 2 0 Starch/carbohydrate-binding module (family 53) STAG PF08514.11 CAR23239.1 - 1.3e-27 95.9 5.4 2.7e-27 94.9 3.7 2.6 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 CAR23239.1 - 0.0013 18.8 0.1 1.7 9.1 0.0 3.6 2 0 0 2 2 2 1 HEAT repeat Cas_Csn2 PF09711.10 CAR23239.1 - 0.0055 16.4 7.0 0.014 15.0 0.7 2.8 2 0 0 2 2 2 1 CRISPR-associated protein (Cas_Csn2) Pilus_CpaD PF09476.10 CAR23239.1 - 0.1 12.4 0.8 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Nipped-B_C PF12830.7 CAR23239.1 - 0.15 12.0 0.1 0.15 12.0 0.1 3.2 3 2 1 4 4 4 0 Sister chromatid cohesion C-terminus Flu_NS2 PF00601.19 CAR23239.1 - 0.15 12.3 3.1 3 8.2 0.7 3.2 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Ipi1_N PF12333.8 CAR23239.1 - 0.34 11.5 1.8 0.96 10.1 0.0 2.7 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation MMgT PF10270.9 CAR23240.1 - 2.2e-23 82.5 0.0 2.9e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter ANAPC_CDC26 PF10471.9 CAR23241.1 - 1.7e-14 54.4 1.1 2.1e-14 54.1 1.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 RINGv PF12906.7 CAR23242.1 - 3.6e-16 59.0 5.3 6.7e-16 58.2 5.3 1.5 1 0 0 1 1 1 1 RING-variant domain TMCO5 PF14992.6 CAR23242.1 - 0.1 12.2 0.3 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 TMCO5 family zf-RING_2 PF13639.6 CAR23242.1 - 0.34 11.3 6.2 0.84 10.0 6.3 1.6 1 1 0 1 1 1 0 Ring finger domain Peptidase_C48 PF02902.19 CAR23243.1 - 5e-39 134.4 2.8 9.5e-39 133.5 2.8 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Com_YlbF PF06133.11 CAR23243.1 - 0.11 13.1 0.3 0.33 11.6 0.3 1.8 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Tim44 PF04280.15 CAR23244.1 - 2.3e-35 121.8 0.0 4.6e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain Halogen_Hydrol PF10112.9 CAR23244.1 - 0.099 12.7 0.7 0.25 11.4 0.3 1.9 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF1770 PF08589.10 CAR23245.1 - 0.067 14.2 0.1 0.15 13.0 0.0 1.6 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1770) RNA_pol_A_bac PF01000.26 CAR23246.1 - 3.2e-32 111.2 0.1 7.7e-32 110.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CAR23246.1 - 8.9e-20 69.9 0.0 1.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.21 CAR23247.1 - 1.5e-26 93.3 0.0 1.9e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein BtpA PF03437.15 CAR23247.1 - 0.18 11.2 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 BtpA family DUF4602 PF15375.6 CAR23248.1 - 0.064 13.6 20.2 4 7.7 20.2 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) CDC45 PF02724.14 CAR23248.1 - 1.3 7.2 10.2 2.1 6.6 10.2 1.3 1 0 0 1 1 1 0 CDC45-like protein HLH PF00010.26 CAR23249.1 - 5.2e-13 48.7 0.2 1.2e-12 47.6 0.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SUIM_assoc PF16619.5 CAR23249.1 - 4.1e-05 23.6 5.2 0.00013 22.0 5.2 1.9 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Lactamase_B_3 PF13483.6 CAR23249.1 - 0.0026 17.7 0.3 0.0049 16.8 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Spt20 PF12090.8 CAR23249.1 - 0.0054 16.4 3.8 0.009 15.6 3.8 1.6 1 0 0 1 1 1 1 Spt20 family UCR_hinge PF02320.16 CAR23250.1 - 7.3e-26 90.2 5.3 1.3e-25 89.3 5.3 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein BUD22 PF09073.10 CAR23250.1 - 0.064 12.6 34.0 0.073 12.4 34.0 1.0 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 CAR23250.1 - 0.16 10.4 27.4 0.24 9.8 27.4 1.3 1 0 0 1 1 1 0 Mpp10 protein PAF PF15715.5 CAR23250.1 - 0.73 10.4 13.8 0.097 13.3 8.8 1.8 1 1 1 2 2 2 0 PCNA-associated factor histone like domain Mitofilin PF09731.9 CAR23250.1 - 2 7.2 15.9 2.2 7.0 15.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nop14 PF04147.12 CAR23250.1 - 2.7 6.1 36.0 3.2 5.8 36.0 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CAR23250.1 - 4.9 6.5 39.7 6.1 6.2 39.7 1.1 1 0 0 1 1 1 0 SDA1 SpoIIIAH PF12685.7 CAR23250.1 - 6.4 6.5 16.7 10 5.9 16.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Raftlin PF15250.6 CAR23250.1 - 7.5 5.2 11.1 8.2 5.0 11.1 1.1 1 0 0 1 1 1 0 Raftlin Ribosomal_L29e PF01779.17 CAR23251.1 - 3.8e-24 84.7 8.6 5.2e-24 84.3 8.6 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.22 CAR23252.1 - 1.3e-16 60.1 0.1 2.4e-11 43.3 0.0 3.1 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR23252.1 - 0.055 13.1 0.0 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR23252.1 - 0.11 12.4 0.0 3.4 7.6 0.0 2.8 2 1 1 3 3 3 0 Occluded RNA-recognition motif MSA-2c PF12238.8 CAR23252.1 - 0.19 11.7 2.4 0.45 10.5 2.4 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Ribosomal_L2_C PF03947.18 CAR23253.1 - 1.5e-44 151.2 3.8 2.6e-44 150.4 3.8 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CAR23253.1 - 6.9e-14 51.6 0.1 1.9e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.19 CAR23254.1 - 1e-72 244.1 0.0 9.8e-72 240.9 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR23254.1 - 9.4e-21 74.3 0.6 2.8e-20 72.8 0.1 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CAR23254.1 - 5.7e-16 59.6 10.1 5.7e-16 59.6 10.1 6.1 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 CAR23254.1 - 1.8e-09 37.8 8.5 1.8e-09 37.8 8.5 4.0 2 2 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CAR23254.1 - 3.1e-08 33.8 1.7 3.5e-05 23.8 0.2 4.0 4 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR23254.1 - 4.6e-05 23.1 0.4 0.00013 21.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain BRE1 PF08647.11 CAR23254.1 - 0.00087 19.3 5.9 0.00087 19.3 5.9 9.0 5 2 4 10 10 9 1 BRE1 E3 ubiquitin ligase DUF745 PF05335.13 CAR23254.1 - 0.0014 18.4 1.9 0.0014 18.4 1.9 5.7 2 2 4 7 7 7 1 Protein of unknown function (DUF745) UPF0242 PF06785.11 CAR23254.1 - 0.0055 16.8 15.2 0.0055 16.8 15.2 5.9 3 2 2 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus ABC_tran PF00005.27 CAR23254.1 - 0.017 15.6 0.7 0.13 12.8 0.1 5.4 3 2 1 4 4 2 0 ABC transporter Plasmid_RAQPRD PF09686.10 CAR23254.1 - 0.023 14.9 0.2 0.023 14.9 0.2 4.1 5 1 0 5 5 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) T3SS_needle_E PF08988.10 CAR23254.1 - 0.43 10.8 2.9 2.8 8.2 0.4 3.7 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle DUF3584 PF12128.8 CAR23254.1 - 3.4 5.0 77.6 0.045 11.3 23.0 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 CAR23254.1 - 4 7.5 58.4 0.22 11.6 1.6 8.5 4 3 3 8 8 8 0 Protein of unknown function (DUF1664) FAD_binding_1 PF00667.20 CAR23255.1 - 2.9e-66 223.2 0.0 5.1e-66 222.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CAR23255.1 - 1.5e-08 35.2 0.0 5.1e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 CAR23255.1 - 0.028 14.7 0.0 0.06 13.7 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 CAR23255.1 - 0.16 12.3 0.0 0.81 10.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain DUF383 PF04063.14 CAR23256.1 - 0.036 13.7 1.5 0.11 12.2 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF383) Arm PF00514.23 CAR23256.1 - 0.16 12.1 5.4 6.5 6.9 0.0 4.7 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat BAG PF02179.16 CAR23257.1 - 3e-14 53.2 4.2 5.4e-14 52.4 4.2 1.4 1 0 0 1 1 1 1 BAG domain Lum_binding PF00677.17 CAR23258.1 - 1.5e-44 149.9 2.2 2.6e-22 78.6 0.1 2.3 2 0 0 2 2 2 2 Lumazine binding domain ANAPC4_WD40 PF12894.7 CAR23259.1 - 6.4e-09 36.0 0.8 0.0014 18.8 0.0 5.3 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR23259.1 - 0.0013 19.5 5.7 2.1 9.3 0.1 5.8 7 0 0 7 7 7 1 WD domain, G-beta repeat Lactonase PF10282.9 CAR23259.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PQQ_2 PF13360.6 CAR23259.1 - 0.014 14.9 0.0 0.13 11.8 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 CAR23259.1 - 0.078 12.9 0.2 1.7 8.7 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Cut8 PF08559.10 CAR23260.1 - 3.2e-70 236.5 0.1 3.8e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Noc2 PF03715.13 CAR23260.1 - 0.058 12.6 0.1 0.085 12.1 0.1 1.2 1 0 0 1 1 1 0 Noc2p family Wzy_C PF04932.15 CAR23261.1 - 0.065 12.9 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF1689 PF07954.11 CAR23261.1 - 0.089 13.2 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Beta-APP PF03494.13 CAR23261.1 - 0.098 12.5 0.1 0.55 10.1 0.0 2.2 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) Sedlin_N PF04628.13 CAR23263.1 - 1e-51 174.5 0.0 1.1e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CAR23263.1 - 2.5e-05 24.2 0.1 4.5e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 Sybindin-like family MIS13 PF08202.11 CAR23264.1 - 2e-69 234.2 21.5 2e-69 234.2 21.5 1.8 2 0 0 2 2 2 1 Mis12-Mtw1 protein family SOCS_box PF07525.16 CAR23264.1 - 0.057 13.8 0.5 0.057 13.8 0.5 1.9 2 0 0 2 2 2 0 SOCS box Med22 PF06179.12 CAR23265.1 - 3.1e-22 78.7 1.9 3.7e-22 78.5 1.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex dUTPase PF00692.19 CAR23266.1 - 5.5e-43 145.7 0.0 7.1e-43 145.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase Acetyltransf_7 PF13508.7 CAR23267.1 - 3.9e-06 27.2 0.0 7.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR23267.1 - 0.00086 19.5 0.0 0.0048 17.1 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 CAR23267.1 - 0.051 13.7 0.1 0.14 12.2 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR23267.1 - 0.075 13.0 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein LIME1 PF15332.6 CAR23267.1 - 0.19 11.3 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Peptidase_M16 PF00675.20 CAR23268.1 - 3.6e-32 111.4 0.1 9.8e-32 110.0 0.1 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CAR23268.1 - 3.3e-16 59.4 0.0 1.7e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CAR23268.1 - 2.9e-15 56.7 0.0 3e-06 27.4 0.0 4.3 4 0 0 4 4 4 3 Peptidase M16 inactive domain Cyclin_N PF00134.23 CAR23270.1 - 1.1e-40 138.4 0.4 2.3e-40 137.3 0.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR23270.1 - 3.5e-21 75.5 0.0 1.6e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain TbpB_A PF17484.2 CAR23270.1 - 1.3 9.7 4.2 0.6 10.9 0.9 1.9 1 1 1 2 2 2 0 N-Lobe handle Tf-binding protein B Cyclin_N PF00134.23 CAR23271.1 - 2.7e-40 137.1 0.2 1.8e-39 134.4 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR23271.1 - 1.8e-31 108.7 0.3 8.9e-31 106.5 0.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain SET PF00856.28 CAR23271.1 - 4.9 7.5 5.4 9.6 6.6 4.8 1.5 1 1 0 1 1 1 0 SET domain IF-2B PF01008.17 CAR23272.1 - 1e-81 274.2 0.0 1.2e-81 274.0 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ATP-synt_S1 PF05827.12 CAR23273.1 - 0.12 12.3 1.6 0.23 11.3 1.6 1.4 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) VMA21 PF09446.10 CAR23274.1 - 3.8e-11 42.9 14.8 2.4e-10 40.4 14.8 1.9 1 1 0 1 1 1 1 VMA21-like domain BRI3BP PF14965.6 CAR23274.1 - 0.0092 15.5 0.4 0.0095 15.5 0.4 1.0 1 0 0 1 1 1 1 Negative regulator of p53/TP53 Med18 PF09637.10 CAR23275.1 - 2.4e-56 191.3 0.0 3.9e-56 190.7 0.0 1.3 1 1 0 1 1 1 1 Med18 protein Pescadillo_N PF06732.11 CAR23276.1 - 1.2e-122 408.8 0.6 1.2e-122 408.8 0.6 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CAR23276.1 - 3.4e-09 37.0 0.0 8.1e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CAR23276.1 - 0.0094 16.2 0.1 0.085 13.2 0.0 2.5 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT PF00533.26 CAR23276.1 - 0.02 15.3 0.0 0.069 13.5 0.0 2.0 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CAF1 PF04857.20 CAR23276.1 - 5.4 6.1 10.7 12 5.0 10.7 1.6 1 0 0 1 1 1 0 CAF1 family ribonuclease Glu-tRNAGln PF02686.15 CAR23277.1 - 0.018 15.3 0.1 0.029 14.7 0.1 1.6 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF4791 PF16039.5 CAR23277.1 - 0.18 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4791) Rhomboid PF01694.22 CAR23278.1 - 5.1e-33 114.2 15.4 5.1e-33 114.2 15.4 1.6 2 0 0 2 2 2 1 Rhomboid family RabGAP-TBC PF00566.18 CAR23279.1 - 3.2e-52 177.3 0.1 8.6e-52 175.9 0.1 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CAR23279.1 - 8.1e-15 54.7 0.1 2.3e-14 53.2 0.1 1.8 1 0 0 1 1 1 1 GRAM domain PH_TFIIH PF08567.11 CAR23279.1 - 0.018 15.3 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Vps36_ESCRT-II PF11605.8 CAR23279.1 - 0.078 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 Fmp27_WPPW PF10359.9 CAR23280.1 - 5.2e-124 414.7 0.4 9.5e-124 413.9 0.4 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CAR23280.1 - 1.2e-96 324.5 1.0 1.2e-96 324.5 1.0 2.2 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CAR23280.1 - 1.5e-50 171.4 0.1 7.6e-50 169.0 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CAR23280.1 - 3.1e-31 108.4 0.2 1.2e-30 106.5 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CAR23280.1 - 5.7e-14 52.7 0.5 5.4e-13 49.5 0.2 3.0 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain HIP1_clath_bdg PF16515.5 CAR23280.1 - 2.3 8.9 5.4 2.8 8.6 1.6 2.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C4H2 PF10146.9 CAR23280.1 - 2.5 8.3 6.2 0.31 11.3 0.2 2.6 3 0 0 3 3 3 0 Zinc finger-containing protein Telomere_reg-2 PF10193.9 CAR23281.1 - 8e-22 77.7 0.6 8e-22 77.7 0.6 3.2 4 0 0 4 4 4 1 Telomere length regulation protein JHD PF17811.1 CAR23281.1 - 0.07 13.7 0.2 2.8 8.5 0.0 2.9 3 0 0 3 3 3 0 Jumonji helical domain DUF1644 PF07800.12 CAR23281.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Peptidase_C50 PF03568.17 CAR23282.1 - 2.4e-132 441.8 0.0 3.5e-132 441.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 CAR23282.1 - 0.0022 17.5 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 CHAT domain RRG8 PF17068.5 CAR23283.1 - 1.5e-100 336.2 0.0 1.7e-100 336.0 0.0 1.0 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial Flavin_Reduct PF01613.18 CAR23284.1 - 2.8e-29 102.2 0.0 3.3e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PH PF00169.29 CAR23285.1 - 0.0039 17.7 1.6 0.0053 17.3 0.3 1.9 2 0 0 2 2 2 1 PH domain RNAse_A_bac PF18431.1 CAR23285.1 - 0.049 14.6 1.4 3.4 8.7 0.0 3.0 1 1 1 2 2 2 0 Bacterial CdiA-CT RNAse A domain TRAM_LAG1_CLN8 PF03798.16 CAR23286.1 - 3.1e-29 102.1 13.9 5.8e-29 101.2 13.9 1.4 1 0 0 1 1 1 1 TLC domain ADH_N PF08240.12 CAR23287.1 - 3e-28 97.9 0.3 6e-28 96.9 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR23287.1 - 3.6e-27 94.9 1.2 6.1e-27 94.2 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR23287.1 - 8.7e-07 30.1 0.1 1.8e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2284 PF10050.9 CAR23287.1 - 0.14 11.9 0.2 0.28 10.9 0.2 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) CDP-OH_P_transf PF01066.21 CAR23288.1 - 4.9e-14 52.9 0.4 4.9e-14 52.9 0.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribosomal_L7Ae PF01248.26 CAR23289.1 - 2.8e-23 81.5 0.3 4.4e-23 80.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FGGY_C PF02782.16 CAR23290.1 - 5.7e-70 235.1 1.3 1e-69 234.2 1.1 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CAR23290.1 - 2.1e-45 155.2 0.0 1e-37 130.1 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 CAR23291.1 - 1.3e-67 227.9 3.0 1.7e-67 227.5 3.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein V-SNARE_C PF12352.8 CAR23292.1 - 5.2e-17 61.9 1.4 5.2e-17 61.9 1.4 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus MCU PF04678.13 CAR23292.1 - 0.0039 17.3 8.3 0.061 13.4 0.6 2.3 1 1 1 2 2 2 2 Mitochondrial calcium uniporter Syntaxin-6_N PF09177.11 CAR23292.1 - 0.013 16.0 2.7 0.013 16.0 2.7 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UL17 PF17640.2 CAR23292.1 - 0.029 14.4 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized UL17 PMC2NT PF08066.12 CAR23292.1 - 0.3 11.8 10.5 0.31 11.7 0.5 2.8 2 1 1 3 3 3 0 PMC2NT (NUC016) domain FUSC PF04632.12 CAR23292.1 - 1.1 7.7 7.5 1.1 7.7 0.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family CortBP2 PF09727.9 CAR23292.1 - 2.2 8.2 12.8 0.63 9.9 8.6 1.9 1 1 1 2 2 2 0 Cortactin-binding protein-2 Metal_resist PF13801.6 CAR23292.1 - 4.9 7.4 6.4 0.5 10.6 0.7 2.1 1 1 1 2 2 2 0 Heavy-metal resistance DUF745 PF05335.13 CAR23292.1 - 7 6.3 8.4 2.8 7.6 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Autophagy_act_C PF03987.15 CAR23293.1 - 5.6e-09 36.4 0.2 1.1e-07 32.4 0.1 2.5 2 1 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.6 CAR23294.1 - 1e-31 109.2 0.1 1.6e-31 108.5 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CAR23294.1 - 1.8e-09 38.0 7.6 1.8e-09 38.0 7.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CAR23294.1 - 3e-08 34.0 8.0 3e-08 34.0 8.0 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CAR23294.1 - 5.4e-08 32.8 3.4 5.4e-08 32.8 3.4 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CAR23294.1 - 0.0057 17.2 6.6 0.0057 17.2 6.6 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CAR23294.1 - 0.006 16.5 1.2 0.006 16.5 1.2 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 CAR23294.1 - 0.01 16.0 0.4 0.49 10.6 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CAR23294.1 - 0.02 15.0 7.5 0.02 15.0 7.5 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 CAR23294.1 - 6.6 7.7 13.5 9.7 7.2 2.9 2.9 2 1 1 3 3 3 0 4Fe-4S double cluster binding domain SHR-BD PF06650.12 CAR23295.1 - 3.3e-88 295.6 0.9 4.6e-87 291.8 0.6 2.4 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 CAR23295.1 - 5.4e-84 281.3 5.7 1.3e-82 276.8 1.1 4.9 5 0 0 5 5 5 1 Repeating coiled region of VPS13 VPS13 PF16908.5 CAR23295.1 - 3.8e-75 252.7 11.0 8.7e-74 248.3 1.1 4.5 4 0 0 4 4 4 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CAR23295.1 - 2.7e-74 248.8 6.9 3.6e-69 232.1 0.6 3.1 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CAR23295.1 - 3.9e-37 126.9 1.4 9e-37 125.7 0.1 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CAR23295.1 - 0.028 14.8 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Imm10 PF15588.6 CAR23295.1 - 0.23 11.6 1.0 4.8 7.4 0.4 2.8 2 0 0 2 2 2 0 Immunity protein 10 DUF3040 PF11239.8 CAR23295.1 - 0.27 11.5 0.4 0.75 10.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) T4_baseplate PF12322.8 CAR23295.1 - 0.59 9.6 6.0 0.29 10.6 0.2 3.1 3 0 0 3 3 3 0 T4 bacteriophage base plate protein Fungal_trans PF04082.18 CAR23296.1 - 3.5e-16 59.1 2.3 3.5e-16 59.1 2.3 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23296.1 - 2.6e-09 37.0 13.0 2.6e-09 37.0 13.0 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 CAR23297.1 - 3.1e-62 209.9 14.6 3.1e-62 209.9 14.6 1.4 2 0 0 2 2 2 1 RTA1 like protein Ecm29 PF13001.7 CAR23298.1 - 1.6e-132 442.7 0.9 3.8e-132 441.5 0.3 2.0 2 0 0 2 2 2 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 CAR23298.1 - 5e-06 27.0 0.0 0.00054 20.5 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CAR23298.1 - 7.5e-06 25.8 3.7 0.51 10.7 0.0 7.2 8 0 0 8 8 8 1 HEAT repeat MMS19_C PF12460.8 CAR23298.1 - 7.5e-06 25.3 0.1 0.1 11.7 0.1 4.3 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 CAR23298.1 - 0.0025 18.3 0.2 55 4.4 0.0 5.5 6 0 0 6 6 6 0 HEAT-like repeat CLASP_N PF12348.8 CAR23298.1 - 0.02 14.5 2.7 3.3 7.2 0.0 4.1 4 1 0 4 4 4 0 CLASP N terminal TFCD_C PF12612.8 CAR23298.1 - 0.059 13.2 0.3 0.32 10.8 0.0 2.5 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal ubiquitin PF00240.23 CAR23299.1 - 2.7e-134 437.1 20.4 5.3e-33 112.6 0.6 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 CAR23299.1 - 3.9e-63 209.2 21.0 3.2e-15 55.7 0.7 4.2 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR23299.1 - 1.3e-21 76.8 12.7 0.00063 20.1 0.2 6.1 4 4 1 5 5 5 4 Ubiquitin-like domain TBK1_ULD PF18396.1 CAR23299.1 - 9.3e-16 57.5 3.4 0.035 14.0 0.0 4.4 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CAR23299.1 - 5.1e-14 52.4 9.7 0.036 14.4 0.3 4.2 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR23299.1 - 1e-13 51.3 2.6 0.15 12.2 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CAR23299.1 - 3.1e-12 47.0 2.2 0.56 10.8 0.0 4.6 1 1 3 5 5 5 4 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CAR23299.1 - 6.7e-06 26.1 24.0 24 5.0 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 CAR23299.1 - 1e-05 25.0 0.4 2.9 7.2 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 CAR23299.1 - 2.6e-05 24.3 3.2 19 5.5 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 CAR23299.1 - 2.6e-05 24.5 0.0 43 4.6 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 CAR23299.1 - 4.5e-05 23.2 5.7 8.1 6.4 0.1 4.4 4 0 0 4 4 4 0 ACT domain UDP-g_GGTase PF06427.11 CAR23299.1 - 8.6e-05 22.6 5.6 11 6.2 0.0 4.3 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 CAR23299.1 - 0.00018 22.2 0.3 78 4.1 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain DUF969 PF06149.12 CAR23299.1 - 0.0021 17.5 0.0 36 3.7 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) YcgR_2 PF12945.7 CAR23299.1 - 0.0039 17.3 6.2 42 4.4 0.1 4.2 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 CAR23299.1 - 0.01 16.4 0.1 1.9e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 CAR23299.1 - 0.024 15.2 1.6 1.7e+02 2.9 0.0 4.2 4 0 0 4 4 4 0 ACT domain ORF11CD3 PF10549.9 CAR23299.1 - 0.025 14.7 0.0 1.3e+02 2.8 0.0 4.2 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 CAR23299.1 - 0.39 10.9 5.8 1.5e+02 2.6 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 CAR23299.1 - 0.5 10.6 27.2 8.7 6.7 1.4 4.4 4 0 0 4 4 4 0 Tash protein PEST motif Myosin_N PF02736.19 CAR23299.1 - 0.64 9.9 5.8 1.5e+02 2.3 0.0 4.9 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 CAR23299.1 - 7.1 6.4 9.3 1.4e+02 2.3 0.1 4.1 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain ENTH PF01417.20 CAR23300.1 - 2.8e-32 111.4 0.9 3.7e-32 111.0 0.9 1.2 1 0 0 1 1 1 1 ENTH domain SAP18 PF06487.12 CAR23300.1 - 0.02 15.0 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Prp19 PF08606.11 CAR23301.1 - 1.1e-28 99.0 2.3 2.8e-28 97.7 2.3 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like TIP120 PF08623.10 CAR23301.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) GIT_CC PF16559.5 CAR23301.1 - 5.9 6.8 5.6 2.9 7.8 0.3 2.6 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor RabGAP-TBC PF00566.18 CAR23302.1 - 0.0001 22.0 7.2 0.0013 18.4 0.2 3.5 4 0 0 4 4 4 2 Rab-GTPase-TBC domain SKG6 PF08693.10 CAR23303.1 - 0.026 13.9 6.3 0.13 11.6 6.3 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 CAR23303.1 - 0.073 12.8 0.4 0.073 12.8 0.4 2.7 2 2 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4328 PF14219.6 CAR23303.1 - 0.26 10.8 3.5 0.34 10.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) zf-C2H2 PF00096.26 CAR23304.1 - 2.6e-05 24.4 23.3 5.5e-05 23.4 2.0 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR23304.1 - 0.00088 19.6 3.0 0.00088 19.6 3.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR23304.1 - 0.0035 18.1 1.6 0.0035 18.1 1.6 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAR23304.1 - 0.024 14.6 1.2 0.053 13.5 1.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.7 CAR23304.1 - 0.032 14.6 1.2 0.067 13.6 0.4 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAR23304.1 - 0.036 14.4 0.2 0.036 14.4 0.2 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CAR23304.1 - 0.33 11.3 7.8 0.21 11.9 4.8 2.3 2 1 1 3 3 3 0 C2H2-type zinc ribbon DUF629 PF04780.12 CAR23304.1 - 0.39 9.2 5.8 3.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2HE PF16278.5 CAR23304.1 - 0.99 9.9 8.9 0.35 11.4 5.1 2.3 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 CAR23304.1 - 4.4 8.0 14.0 4.5 8.0 1.4 3.8 2 1 2 4 4 4 0 FOXP coiled-coil domain CLP1_P PF16575.5 CAR23305.1 - 1.6e-31 109.5 0.0 2.5e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 CAR23305.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 CAR23305.1 - 0.043 13.0 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AMO PF02461.16 CAR23305.1 - 0.046 13.5 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase AAA_14 PF13173.6 CAR23305.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAR23305.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 CAR23306.1 - 1.2e-93 310.5 0.5 1.4e-46 158.2 0.0 3.7 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR23306.1 - 2.3e-21 75.3 1.4 1.7e-09 37.4 0.8 3.0 2 1 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CAR23306.1 - 3.6e-14 52.8 0.0 8.9e-07 28.8 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR23306.1 - 3.5e-13 50.3 2.6 7.2e-05 23.2 0.0 4.3 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CAR23306.1 - 1.6e-10 41.4 0.4 0.014 15.7 0.0 4.9 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.14 CAR23306.1 - 2.2e-10 40.9 0.0 0.00074 19.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CAR23306.1 - 9.7e-10 38.8 0.0 0.00036 20.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CAR23306.1 - 1.2e-09 38.1 1.7 1.2e-05 25.2 0.1 3.2 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CAR23306.1 - 2e-09 37.6 0.1 0.0012 18.9 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CAR23306.1 - 7.2e-09 35.3 0.0 0.00036 19.9 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CAR23306.1 - 3e-08 34.3 0.2 0.0023 18.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 CAR23306.1 - 4.8e-08 33.1 0.0 0.023 14.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 CAR23306.1 - 1.1e-07 32.4 0.1 0.011 16.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter RNA_helicase PF00910.22 CAR23306.1 - 2.3e-07 31.1 0.0 0.017 15.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 CAR23306.1 - 8.2e-07 28.5 0.0 0.044 13.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 CAR23306.1 - 2.8e-06 27.2 0.1 0.044 13.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 CAR23306.1 - 3e-06 27.3 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain Mg_chelatase PF01078.21 CAR23306.1 - 3.8e-06 26.4 0.3 0.05 13.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAR23306.1 - 7.7e-06 25.8 0.0 0.07 13.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAR23306.1 - 8.8e-06 26.1 0.9 0.081 13.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.6 CAR23306.1 - 9.9e-06 26.0 3.0 0.14 12.6 0.0 4.5 4 0 0 4 4 4 1 AAA domain Cytidylate_kin2 PF13189.6 CAR23306.1 - 6.4e-05 23.2 0.0 0.0075 16.4 0.0 3.1 3 0 0 3 3 2 1 Cytidylate kinase-like family NACHT PF05729.12 CAR23306.1 - 6.8e-05 22.9 0.0 0.6 10.0 0.0 3.1 3 0 0 3 3 3 2 NACHT domain TsaE PF02367.17 CAR23306.1 - 7.9e-05 22.7 0.0 0.61 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CAR23306.1 - 8e-05 22.3 0.0 1.5 8.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain ATPase_2 PF01637.18 CAR23306.1 - 8.9e-05 22.5 0.1 2.2 8.1 0.0 4.2 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea SKI PF01202.22 CAR23306.1 - 9.5e-05 22.6 0.1 0.24 11.5 0.0 3.4 3 0 0 3 3 2 1 Shikimate kinase Sigma54_activat PF00158.26 CAR23306.1 - 0.00015 21.5 0.0 0.27 10.9 0.0 3.2 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 CAR23306.1 - 0.00017 21.1 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 CAR23306.1 - 0.00027 20.2 0.1 0.14 11.3 0.0 2.9 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 CAR23306.1 - 0.00054 19.8 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CAR23306.1 - 0.00055 19.7 0.0 0.83 9.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CAR23306.1 - 0.0012 19.0 0.0 2.8 8.1 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain CPT PF07931.12 CAR23306.1 - 0.0013 18.6 0.0 0.029 14.2 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 CAR23306.1 - 0.0016 17.8 0.0 1.6 8.0 0.0 3.2 3 0 0 3 3 3 1 KaiC NB-ARC PF00931.22 CAR23306.1 - 0.0017 17.6 0.0 1 8.5 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain SRPRB PF09439.10 CAR23306.1 - 0.0021 17.5 0.0 1.8 8.0 0.0 3.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Parvo_NS1 PF01057.17 CAR23306.1 - 0.0025 16.9 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.16 CAR23306.1 - 0.0043 16.0 0.1 7 5.4 0.0 3.3 4 0 0 4 4 3 0 AFG1-like ATPase PduV-EutP PF10662.9 CAR23306.1 - 0.014 15.1 0.0 7.6 6.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 CAR23306.1 - 0.017 14.8 2.0 0.54 9.9 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase PhoH PF02562.16 CAR23306.1 - 0.02 14.4 0.1 2.8 7.3 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein DUF5449 PF17528.2 CAR23306.1 - 0.023 14.4 0.5 0.05 13.4 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5449) AAA_19 PF13245.6 CAR23306.1 - 0.027 14.8 0.1 9.5 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CAR23306.1 - 0.034 14.1 0.1 12 5.7 0.0 2.8 3 0 0 3 3 2 0 NTPase Phage_Gp17 PF17549.2 CAR23306.1 - 0.049 13.7 0.8 0.15 12.1 0.8 1.8 1 0 0 1 1 1 0 Gene Product 17 RsgA_GTPase PF03193.16 CAR23306.1 - 0.057 13.3 0.0 0.87 9.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 CAR23306.1 - 0.059 13.5 2.5 3.1 7.9 0.0 3.8 4 0 0 4 4 4 0 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR23306.1 - 0.076 12.5 1.3 2 8.0 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B E2_bind PF08825.10 CAR23306.1 - 0.097 12.8 0.6 0.57 10.4 0.1 2.6 2 0 0 2 2 1 0 E2 binding domain TniB PF05621.11 CAR23306.1 - 0.11 11.9 0.0 18 4.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_29 PF13555.6 CAR23306.1 - 0.17 11.7 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.6 CAR23306.1 - 0.21 11.3 17.4 0.61 9.8 0.0 4.1 3 1 0 3 3 2 0 AAA domain Phage_Nu1 PF07471.12 CAR23306.1 - 0.21 11.3 4.4 0.21 11.4 2.7 1.8 2 0 0 2 2 1 0 Phage DNA packaging protein Nu1 Hydin_ADK PF17213.3 CAR23306.1 - 0.51 10.6 13.2 0.74 10.1 0.0 3.9 3 1 0 3 3 2 0 Hydin Adenylate kinase-like domain AAA_23 PF13476.6 CAR23306.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.9 4 1 0 4 4 2 0 AAA domain LegC3_N PF18654.1 CAR23307.1 - 0.0094 15.2 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 LegC3 N-terminal coiled-coil domain KH_1 PF00013.29 CAR23308.1 - 9.8e-16 57.3 1.3 3.8e-06 26.6 0.0 5.1 5 0 0 5 5 5 3 KH domain Nrap_D4 PF17405.2 CAR23309.1 - 0.021 14.2 0.4 0.033 13.5 0.4 1.3 1 0 0 1 1 1 0 Nrap protein nucleotidyltransferase domain 4 HDV_ag PF01517.18 CAR23309.1 - 0.034 13.9 1.5 0.062 13.1 1.5 1.5 1 1 0 1 1 1 0 Hepatitis delta virus delta antigen Phosphodiest PF01663.22 CAR23310.1 - 4.5e-13 49.5 0.1 8.4e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CAR23310.1 - 0.0045 16.4 0.2 0.0082 15.5 0.2 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CAR23310.1 - 0.005 16.3 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Zn_clus PF00172.18 CAR23311.1 - 1.9e-09 37.4 10.7 3.7e-09 36.6 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CAR23312.1 - 5.7e-34 117.6 26.7 5.7e-34 117.6 26.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR23312.1 - 3.5e-12 45.9 9.1 3.5e-12 45.9 9.1 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CAR23312.1 - 5.1e-08 31.8 3.7 8.9e-08 31.0 3.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Syntaphilin PF15290.6 CAR23312.1 - 0.76 9.4 2.4 1.2 8.7 2.4 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Creatinase_N_2 PF16189.5 CAR23313.1 - 7.7e-41 139.9 0.1 2.7e-40 138.1 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CAR23313.1 - 1.7e-40 139.0 0.0 3.1e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CAR23313.1 - 1e-21 76.8 1.0 3.3e-21 75.1 0.4 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CAR23313.1 - 3.4e-11 43.9 0.0 2.2e-09 38.0 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Fe-S_biosyn PF01521.20 CAR23314.1 - 2e-17 63.4 0.0 4.6e-17 62.2 0.0 1.6 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis AAA_2 PF07724.14 CAR23315.1 - 8.5e-48 162.7 0.0 2e-46 158.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CAR23315.1 - 1.3e-26 92.5 0.5 1.3e-26 92.5 0.5 3.1 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CAR23315.1 - 4.4e-25 87.5 0.5 2e-24 85.4 0.5 2.3 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CAR23315.1 - 9.6e-24 84.3 0.1 5.5e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR23315.1 - 1.8e-16 60.4 0.0 4.9e-09 36.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CAR23315.1 - 8.7e-15 54.6 4.9 1e-09 38.4 0.3 3.7 3 1 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 CAR23315.1 - 3e-12 46.6 0.0 1.5e-08 34.6 0.0 2.9 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 CAR23315.1 - 1.9e-08 34.9 10.2 0.00029 21.3 0.0 5.3 5 1 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 CAR23315.1 - 1.1e-07 32.2 0.3 0.042 14.1 0.0 4.3 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 CAR23315.1 - 4.2e-06 26.3 0.1 0.012 15.0 0.0 4.5 2 1 1 3 3 3 1 Bacterial TniB protein AAA_14 PF13173.6 CAR23315.1 - 2.7e-05 24.2 0.2 0.4 10.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 CAR23315.1 - 8.4e-05 22.4 0.0 0.037 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CAR23315.1 - 0.00011 21.5 3.9 0.2 10.8 0.0 3.5 4 0 0 4 4 3 2 TIP49 P-loop domain NACHT PF05729.12 CAR23315.1 - 0.00012 22.0 0.1 0.7 9.8 0.0 3.3 3 0 0 3 3 3 2 NACHT domain Mg_chelatase PF01078.21 CAR23315.1 - 0.00019 20.9 0.0 0.15 11.5 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CAR23315.1 - 0.00059 20.0 0.0 0.14 12.3 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CAR23315.1 - 0.00066 19.5 0.1 2 8.3 0.0 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CAR23315.1 - 0.00075 19.0 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CAR23315.1 - 0.0013 18.5 0.0 0.21 11.3 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Torsin PF06309.11 CAR23315.1 - 0.0023 18.0 0.0 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 Torsin TsaE PF02367.17 CAR23315.1 - 0.0049 16.9 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CAR23315.1 - 0.0061 15.9 0.2 0.63 9.3 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin ATPase_2 PF01637.18 CAR23315.1 - 0.0077 16.2 8.1 1.4 8.7 0.1 4.2 4 1 1 5 5 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CAR23315.1 - 0.0083 16.5 0.0 2 8.7 0.0 3.5 2 1 1 3 3 3 1 AAA domain Roc PF08477.13 CAR23315.1 - 0.014 15.6 0.0 9.3 6.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 CAR23315.1 - 0.024 15.2 1.4 3.5 8.2 0.0 4.2 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.22 CAR23315.1 - 0.077 13.4 0.2 22 5.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Spc7 PF08317.11 CAR23315.1 - 0.12 11.2 13.9 0.24 10.2 13.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 CAR23315.1 - 0.34 9.9 9.5 0.76 8.8 9.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 rve_3 PF13683.6 CAR23315.1 - 0.41 10.4 1.6 19 5.1 0.6 3.2 2 1 1 3 3 3 0 Integrase core domain ABC_tran PF00005.27 CAR23315.1 - 0.85 10.1 6.3 6.2 7.3 0.0 4.2 4 0 0 4 4 4 0 ABC transporter BLOC1_2 PF10046.9 CAR23315.1 - 2.2 8.6 7.2 5.5 7.4 4.9 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4337 PF14235.6 CAR23315.1 - 3.8 7.6 8.0 11 6.1 8.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Rx_N PF18052.1 CAR23315.1 - 5.1 7.4 8.1 7.8 6.8 0.7 2.9 2 0 0 2 2 2 0 Rx N-terminal domain V_ATPase_I PF01496.19 CAR23315.1 - 5.8 4.7 7.5 10 3.9 7.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_1 PF00076.22 CAR23316.1 - 4.7e-27 93.6 1.9 1.2e-12 47.5 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR23316.1 - 0.0014 18.5 0.0 0.31 10.9 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CAR23316.1 - 0.0079 16.2 0.0 1.6 8.8 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif NPR3 PF03666.13 CAR23317.1 - 4.1e-156 520.4 3.0 4.1e-156 520.4 3.0 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Adenylsucc_synt PF00709.21 CAR23317.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase EMP24_GP25L PF01105.24 CAR23318.1 - 6.9e-39 133.7 0.0 8.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MRF_C1 PF13887.6 CAR23318.1 - 0.023 13.8 0.1 0.077 12.2 0.0 1.8 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Lipoprotein_1 PF00820.19 CAR23318.1 - 0.085 11.9 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein Metallophos PF00149.28 CAR23319.1 - 3.1e-40 138.9 0.0 4e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR23319.1 - 8.2e-22 77.4 2.7 8.3e-22 77.4 1.1 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Yip1 PF04893.17 CAR23320.1 - 3e-07 30.3 5.3 4e-07 29.9 5.3 1.3 1 0 0 1 1 1 1 Yip1 domain DUF5562 PF17717.1 CAR23320.1 - 0.041 13.9 0.6 0.075 13.0 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5562) Kelch_6 PF13964.6 CAR23321.1 - 6.7e-16 57.9 4.5 3.6e-09 36.6 0.0 5.5 4 1 1 5 5 5 2 Kelch motif Kelch_4 PF13418.6 CAR23321.1 - 1.3e-12 47.5 1.0 3.5e-06 26.9 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CAR23321.1 - 1.5e-12 46.9 0.2 0.00011 21.6 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CAR23321.1 - 2.2e-09 37.4 0.6 8.5e-06 25.9 0.0 4.8 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.6 CAR23321.1 - 5e-05 23.2 0.0 0.0067 16.4 0.0 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 CAR23321.1 - 0.00049 20.0 3.2 0.026 14.5 0.1 3.9 4 1 0 4 4 4 1 Kelch motif HEAT_EZ PF13513.6 CAR23322.1 - 8.9e-35 118.7 29.2 5.1e-05 23.7 0.0 17.5 17 3 2 19 19 17 8 HEAT-like repeat HEAT PF02985.22 CAR23322.1 - 7.1e-30 100.5 28.0 0.0032 17.6 0.0 20.7 23 0 0 23 23 21 6 HEAT repeat Gcn1_N PF12074.8 CAR23322.1 - 1.9e-27 96.5 1.0 2.6e-12 46.7 0.0 5.3 3 1 2 5 5 5 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_2 PF13646.6 CAR23322.1 - 2.7e-25 88.5 24.3 0.0019 18.6 0.0 13.5 10 3 3 14 14 13 7 HEAT repeats Cnd1 PF12717.7 CAR23322.1 - 2e-13 50.7 24.4 3.3 7.7 0.0 12.9 8 3 4 13 13 13 4 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CAR23322.1 - 3.4e-12 46.4 0.7 6.5e-05 22.6 0.0 7.6 7 2 1 9 9 9 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 CAR23322.1 - 4.5e-11 43.2 8.3 3.3 8.4 0.2 10.4 9 3 4 13 13 13 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CAR23322.1 - 5.8e-11 41.6 31.5 0.012 14.2 6.4 10.0 5 4 2 9 9 9 6 Adaptin N terminal region DUF3385 PF11865.8 CAR23322.1 - 6.9e-09 35.8 10.4 1 9.3 0.4 9.4 8 1 1 10 10 10 2 Domain of unknown function (DUF3385) TIP120 PF08623.10 CAR23322.1 - 1.3e-05 25.1 4.3 0.67 9.7 0.0 6.7 4 2 2 6 6 6 1 TATA-binding protein interacting (TIP20) DUF3535 PF12054.8 CAR23322.1 - 4.6e-05 22.8 2.9 0.46 9.7 0.0 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3535) Ecm29 PF13001.7 CAR23322.1 - 0.00011 21.0 18.3 0.16 10.6 0.3 7.2 8 0 0 8 8 8 3 Proteasome stabiliser FPL PF09758.9 CAR23322.1 - 0.012 15.6 2.8 1 9.4 0.1 4.0 4 0 0 4 4 4 0 Uncharacterised conserved protein Tti2 PF10521.9 CAR23322.1 - 0.015 14.8 3.6 2.2 7.7 0.0 5.3 4 2 0 4 4 4 0 Tti2 family Arm PF00514.23 CAR23322.1 - 0.7 10.0 16.0 9.1 6.5 0.0 8.2 9 1 1 10 10 10 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 CAR23322.1 - 2.5 8.3 9.6 61 3.8 0.5 6.4 7 1 1 8 8 8 0 Required for nuclear transport of RNA pol II C-terminus 1 Hist_deacetyl PF00850.19 CAR23323.1 - 5.1e-83 279.1 0.0 6.2e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MT-A70 PF05063.14 CAR23324.1 - 4.4e-54 183.0 0.1 6.4e-54 182.4 0.1 1.2 1 0 0 1 1 1 1 MT-A70 COX6A PF02046.15 CAR23325.1 - 8.7e-41 138.9 0.4 1e-40 138.7 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.32 CAR23326.1 - 8.5e-17 61.2 3.2 0.0017 19.1 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23326.1 - 0.00028 21.1 0.1 5.8 7.3 0.0 4.9 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S26e PF01283.19 CAR23327.1 - 5.3e-51 171.6 11.3 6.2e-51 171.4 11.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e COX5B PF01215.19 CAR23328.1 - 6.4e-65 216.7 0.1 7.3e-65 216.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Transp_cyt_pur PF02133.15 CAR23329.1 - 2.8e-15 56.0 28.7 2.8e-15 56.0 28.7 2.1 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.19 CAR23330.1 - 8.2e-29 100.2 0.0 1.2e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR23330.1 - 0.00037 20.2 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CAR23330.1 - 0.08 13.1 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cys_Met_Meta_PP PF01053.20 CAR23331.1 - 2.4e-124 414.8 0.0 2.8e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CAR23331.1 - 0.0048 16.1 0.1 0.0074 15.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.18 CAR23332.1 - 5e-10 39.3 9.9 5e-10 39.3 9.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR23332.1 - 2.6e-08 33.2 0.3 1.4e-07 30.9 0.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CAR23333.1 - 5e-12 45.6 11.2 5.9e-06 26.4 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR23333.1 - 6.7e-10 38.9 8.7 5.3e-07 29.8 1.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR23333.1 - 1.5e-09 37.9 10.2 0.0002 21.9 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR23333.1 - 3e-08 33.7 7.6 0.00065 19.9 1.1 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR23333.1 - 3.1e-06 27.4 4.0 0.027 14.9 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CAR23333.1 - 4.5e-05 23.3 7.2 0.0011 18.9 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CAR23333.1 - 0.00078 19.7 2.5 0.0012 19.1 2.5 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CAR23333.1 - 0.0046 16.7 5.7 0.69 9.7 0.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CAR23333.1 - 0.0055 17.4 0.3 1.2 9.8 0.0 2.4 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-BED PF02892.15 CAR23333.1 - 0.0095 15.9 4.8 0.27 11.3 2.0 2.6 1 1 1 2 2 2 1 BED zinc finger Actin_micro PF17003.5 CAR23333.1 - 0.039 13.1 4.7 0.2 10.8 4.7 1.8 1 1 0 1 1 1 0 Putative actin-like family zf-C2HC_2 PF13913.6 CAR23333.1 - 0.047 13.6 6.1 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HNH_5 PF14279.6 CAR23333.1 - 0.067 13.1 1.6 0.55 10.1 0.2 2.4 2 0 0 2 2 2 0 HNH endonuclease zf-C2H2_2 PF12756.7 CAR23333.1 - 0.084 13.2 4.9 5.4 7.4 0.7 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.9 CAR23333.1 - 0.17 12.0 1.2 3.6 7.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger domain zf_C2H2_ZHX PF18387.1 CAR23333.1 - 0.38 10.4 1.2 1.1 9.0 0.5 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 CAR23333.1 - 0.44 9.0 5.7 1.6 7.2 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf_UBZ PF18439.1 CAR23333.1 - 0.62 9.7 2.4 4.5 6.9 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 CAR23333.1 - 1.5 9.1 3.6 2.5 8.3 0.2 2.5 2 0 0 2 2 2 0 HNH endonuclease zf-C2HE PF16278.5 CAR23333.1 - 1.5 9.3 6.4 68 4.0 6.4 2.4 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Elf1 PF05129.13 CAR23333.1 - 1.7 8.8 6.0 5.7 7.1 0.6 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Mnd1 PF03962.15 CAR23334.1 - 3.2e-26 91.4 0.6 6.6e-26 90.4 0.6 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 CAR23334.1 - 0.00014 21.9 0.2 0.0007 19.6 0.0 2.3 2 0 0 2 2 2 1 Leucine zipper with capping helix domain NPV_P10 PF05531.12 CAR23334.1 - 0.0069 16.8 0.5 0.051 14.0 0.1 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF2748 PF10871.8 CAR23334.1 - 0.0075 14.9 0.7 0.01 14.5 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2748) Flg_bb_rod PF00460.20 CAR23334.1 - 0.085 12.8 0.3 0.15 12.1 0.3 1.4 1 0 0 1 1 1 0 Flagella basal body rod protein DivIC PF04977.15 CAR23334.1 - 0.089 12.6 1.7 11 5.9 0.1 2.6 2 0 0 2 2 2 0 Septum formation initiator Lge1 PF11488.8 CAR23334.1 - 1.8 8.8 6.1 4.4 7.6 1.8 2.9 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF16 PF01519.16 CAR23334.1 - 2.2 8.8 5.4 5.5 7.5 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 ArfGap PF01412.18 CAR23335.1 - 8.8e-30 103.2 0.0 8.8e-30 103.2 0.0 2.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Med15 PF09606.10 CAR23335.1 - 0.13 10.9 43.8 0.15 10.7 43.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3543 PF12063.8 CAR23336.1 - 1.2e-92 309.9 0.7 2e-92 309.1 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CAR23336.1 - 2.2e-57 194.4 0.0 3.6e-57 193.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23336.1 - 5.2e-44 150.5 0.0 8.4e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.18 CAR23336.1 - 0.013 15.6 6.0 2.6 8.2 0.2 3.9 2 2 0 2 2 2 0 MIT (microtubule interacting and transport) domain AvrM_N PF18247.1 CAR23336.1 - 0.059 13.3 0.0 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain Kinase-like PF14531.6 CAR23336.1 - 0.093 12.0 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 CAR23337.1 - 2.1e-53 181.4 0.0 3.5e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23337.1 - 1.6e-24 86.6 0.0 2.9e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR23337.1 - 0.00029 20.2 0.0 0.00087 18.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR23337.1 - 0.00053 18.9 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAR23337.1 - 0.24 11.3 0.3 2.7 7.9 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Vfa1 PF08432.10 CAR23338.1 - 2.2e-37 129.1 3.3 2.7e-37 128.8 3.3 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 CAR23338.1 - 0.051 13.2 1.5 0.077 12.7 1.5 1.2 1 0 0 1 1 1 0 FAM176 family Sas10_Utp3 PF04000.15 CAR23339.1 - 5.4e-10 39.8 0.2 1.2e-09 38.7 0.2 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Ribosomal_S8e PF01201.22 CAR23340.1 - 1e-44 152.0 0.1 1.8e-44 151.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e PUF PF00806.19 CAR23341.1 - 1.5e-54 178.7 31.9 4.2e-08 32.4 1.8 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HECT PF00632.25 CAR23343.1 - 3.8e-95 318.9 0.0 5e-95 318.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CAR23343.1 - 2.7e-34 116.9 23.8 2.7e-12 46.5 1.9 4.2 4 0 0 4 4 4 3 WW domain C2 PF00168.30 CAR23343.1 - 9.6e-19 67.6 0.0 3.5e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 C2 domain Pkinase PF00069.25 CAR23345.1 - 2.8e-20 72.8 0.0 3.5e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23345.1 - 4.5e-11 42.5 0.0 5.6e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR23345.1 - 2.3e-06 26.7 0.0 3.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CAR23345.1 - 0.038 13.9 0.0 6.8 6.5 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family MRG PF05712.13 CAR23346.1 - 1.2e-43 148.8 0.5 6.1e-43 146.5 0.1 2.1 1 1 0 1 1 1 1 MRG Tudor-knot PF11717.8 CAR23346.1 - 7.4e-09 35.4 0.0 1.8e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF3885 PF13021.6 CAR23346.1 - 0.035 14.2 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Mito_carr PF00153.27 CAR23347.1 - 7.6e-72 237.3 0.1 4.1e-25 87.5 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_8 PF13833.6 CAR23347.1 - 0.0053 16.6 0.2 0.81 9.6 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CAR23347.1 - 0.66 10.5 6.5 1.4 9.4 0.1 4.5 5 1 0 5 5 5 0 EF-hand domain pair EF-hand_1 PF00036.32 CAR23347.1 - 7.1 6.4 6.5 4 7.2 0.2 4.0 4 0 0 4 4 4 0 EF hand Phasin_2 PF09361.10 CAR23348.1 - 0.0063 16.8 0.3 0.013 15.7 0.3 1.6 1 0 0 1 1 1 1 Phasin protein Bud13 PF09736.9 CAR23349.1 - 9e-22 78.0 13.5 3.2e-19 69.8 1.1 3.7 2 2 1 3 3 3 2 Pre-mRNA-splicing factor of RES complex MPM1 PF17234.2 CAR23349.1 - 0.0025 18.1 1.4 0.0025 18.1 1.4 2.2 2 0 0 2 2 2 1 Mitochondrial peculiar membrane protein 1 XRN_N PF03159.18 CAR23350.1 - 3.9e-95 317.9 0.1 3.9e-95 317.9 0.1 2.9 4 0 0 4 4 4 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CAR23350.1 - 6e-89 299.0 7.6 6e-89 299.0 7.6 1.9 2 0 0 2 2 2 1 Xrn1 helical domain XRN1_D1 PF18332.1 CAR23350.1 - 2.9e-64 216.4 0.3 1.4e-63 214.2 0.0 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CAR23350.1 - 7.5e-32 109.4 0.0 2.1e-31 108.0 0.0 1.9 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain Xrn1_D3 PF18194.1 CAR23350.1 - 2.4e-24 85.2 1.1 7.3e-24 83.7 1.1 1.9 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SH3_12 PF18129.1 CAR23350.1 - 2.2e-19 69.3 0.1 4.5e-19 68.3 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Nucleoporin_FG PF13634.6 CAR23351.1 - 2.5e-36 124.4 150.5 5.7e-12 46.3 39.5 5.3 1 1 4 5 5 5 5 Nucleoporin FG repeat region Vps53_N PF04100.12 CAR23351.1 - 0.00097 18.2 2.3 0.071 12.1 0.9 2.1 2 0 0 2 2 2 2 Vps53-like, N-terminal DUF1664 PF07889.12 CAR23351.1 - 0.019 15.0 1.3 1.3 9.1 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Med4 PF10018.9 CAR23351.1 - 1.6 8.4 5.3 6.9 6.3 2.6 2.3 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Mdv1 PF11542.8 CAR23352.1 - 0.27 11.2 1.2 30 4.7 0.2 3.5 2 1 1 3 3 3 0 Mitochondrial division protein 1 Pkinase PF00069.25 CAR23353.1 - 1.2e-37 129.7 0.0 7.9e-34 117.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23353.1 - 1.6e-13 50.6 0.0 1.2e-11 44.4 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CAR23353.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Myb_DNA-bind_4 PF13837.6 CAR23354.1 - 4.6e-06 26.9 0.0 1.7e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR23354.1 - 0.0031 17.7 0.2 0.0059 16.8 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 CAR23354.1 - 0.067 14.2 0.3 0.23 12.5 0.1 1.8 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 CAR23354.1 - 0.54 10.5 2.9 1 9.6 0.2 2.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF2838 PF10998.8 CAR23355.1 - 1.7e-38 131.3 15.8 1.7e-38 131.3 15.8 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) AHSP PF09236.10 CAR23355.1 - 0.027 14.9 0.3 0.23 11.9 0.5 2.2 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein Apolipoprotein PF01442.18 CAR23355.1 - 0.06 13.2 0.8 15 5.4 0.0 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Sec2p PF06428.11 CAR23355.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p HU-CCDC81_bac_2 PF18175.1 CAR23355.1 - 0.13 12.2 0.6 0.29 11.0 0.6 1.6 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Val_tRNA-synt_C PF10458.9 CAR23355.1 - 0.14 12.5 1.9 0.22 11.8 0.3 1.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Uso1_p115_C PF04871.13 CAR23355.1 - 0.32 11.4 2.6 0.38 11.1 0.5 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 CAR23355.1 - 0.33 11.0 3.7 6.4 6.9 0.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC92 PF14916.6 CAR23355.1 - 0.64 9.8 3.2 0.3 10.9 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function PPR_2 PF13041.6 CAR23356.1 - 1.4e-13 50.8 1.8 2.5e-08 34.0 0.1 2.8 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.20 CAR23356.1 - 1.2e-07 31.5 4.1 0.00015 21.8 0.3 3.7 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 CAR23356.1 - 8.1e-07 28.6 0.9 8.6e-05 22.0 0.1 2.6 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CAR23356.1 - 4.7e-05 23.4 0.4 0.00035 20.6 0.2 2.6 1 1 1 2 2 2 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CAR23356.1 - 0.0048 16.6 0.1 0.017 14.8 0.1 2.0 2 0 0 2 2 2 1 PPR repeat HSV_VP16_C PF12149.8 CAR23356.1 - 0.036 14.1 2.5 0.11 12.6 2.5 1.8 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal Cgr1 PF03879.14 CAR23357.1 - 1.8e-31 108.7 29.9 1.8e-31 108.7 29.9 1.4 2 0 0 2 2 2 1 Cgr1 family DUF2048 PF09752.9 CAR23357.1 - 0.027 13.6 3.2 0.033 13.3 3.2 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 MIOX PF05153.15 CAR23358.1 - 1.3e-119 398.4 5.0 1.6e-119 398.1 5.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 CAR23358.1 - 0.0039 17.4 0.3 0.85 9.9 0.0 2.7 3 1 0 3 3 3 2 HD domain DUF1796 PF08795.10 CAR23358.1 - 0.074 13.0 0.2 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) GREB1 PF15782.5 CAR23359.1 - 8.2 3.4 20.9 10 3.1 20.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Glyco_hydro_63 PF03200.16 CAR23360.1 - 8.3e-167 555.9 2.9 6.1e-166 553.0 2.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CAR23360.1 - 3.2e-65 220.4 0.0 5.5e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 CAR23360.1 - 0.051 12.4 0.1 0.11 11.2 0.1 1.5 1 0 0 1 1 1 0 Trehalase Rrn6 PF10214.9 CAR23361.1 - 3.8e-91 306.9 20.7 2e-89 301.3 20.7 2.4 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.20 CAR23362.1 - 2.5e-101 337.9 1.2 4e-101 337.2 1.2 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CAR23362.1 - 9.7e-48 163.1 2.2 2.4e-47 161.8 1.1 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Med3 PF11593.8 CAR23363.1 - 1.4e-31 110.2 56.5 1.1e-27 97.3 56.5 3.2 1 1 0 1 1 1 1 Mediator complex subunit 3 fungal CLZ PF16526.5 CAR23363.1 - 0.17 12.2 0.4 3.2 8.2 0.3 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOBP PF15279.6 CAR23363.1 - 0.24 12.0 21.9 0.32 11.6 21.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Formyl_trans_N PF00551.19 CAR23365.1 - 2.1e-32 112.3 0.0 3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Acyltransferase PF01553.21 CAR23366.1 - 2.4e-10 40.2 0.0 1.4e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase FYVE PF01363.21 CAR23367.1 - 4.6e-14 52.3 7.7 8.4e-14 51.5 7.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger STT3 PF02516.14 CAR23368.1 - 2.9e-151 504.8 43.0 6.5e-148 493.7 41.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF5102 PF17104.5 CAR23369.1 - 0.011 15.7 12.1 0.013 15.6 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5102) FEZ PF07763.13 CAR23369.1 - 0.02 14.7 0.6 0.7 9.6 0.2 2.1 1 1 0 2 2 2 0 FEZ-like protein Haspin_kinase PF12330.8 CAR23370.1 - 1.6e-125 418.9 3.5 1.6e-125 418.9 3.5 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 CAR23370.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CAR23370.1 - 0.047 13.0 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain CHD5 PF04420.14 CAR23371.1 - 2.2e-38 131.6 3.2 2.6e-38 131.4 3.2 1.0 1 0 0 1 1 1 1 CHD5-like protein Med4 PF10018.9 CAR23371.1 - 0.49 10.0 3.4 0.64 9.7 3.4 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CK_II_beta PF01214.18 CAR23372.1 - 2.7e-69 232.6 0.0 3.2e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.13 CAR23373.1 - 2.6e-20 72.7 3.7 7e-20 71.3 1.6 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CAR23373.1 - 1.1e-06 28.6 0.1 2.8e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain POP1 PF06978.11 CAR23373.1 - 0.00098 19.2 1.1 0.0013 18.8 1.1 1.1 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 ATE_C PF04377.15 CAR23374.1 - 2.1e-42 144.9 0.1 3.7e-42 144.1 0.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CAR23374.1 - 2.3e-25 88.8 2.8 4.9e-25 87.7 2.8 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus PhnI PF05861.12 CAR23374.1 - 0.21 10.4 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Aminotran_1_2 PF00155.21 CAR23376.1 - 4.7e-19 68.8 0.0 6.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.32 CAR23377.1 - 4.9e-25 87.3 13.7 3.4e-07 30.9 0.0 7.7 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23377.1 - 1.8e-11 44.2 0.0 0.26 11.6 0.0 5.7 3 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 CAR23377.1 - 1.2e-10 41.5 0.1 3.9e-10 39.8 0.1 1.9 1 0 0 1 1 1 1 TUP1-like enhancer of split HIRA_B PF09453.10 CAR23377.1 - 7.3e-10 38.5 0.0 1.6e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 HIRA B motif IKI3 PF04762.12 CAR23377.1 - 0.0068 14.5 0.2 1.5 6.7 0.1 2.9 3 0 0 3 3 3 2 IKI3 family eIF2A PF08662.11 CAR23377.1 - 0.026 14.4 0.1 0.91 9.4 0.0 3.0 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CAR23377.1 - 0.026 14.5 0.0 8.4 6.5 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 CAR23377.1 - 0.028 14.9 0.1 35 5.0 0.0 3.7 3 1 0 3 3 3 0 PQQ-like domain RCC1_2 PF13540.6 CAR23377.1 - 0.1 12.5 0.2 0.29 11.0 0.2 1.9 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat DNA_pol_phi PF04931.13 CAR23377.1 - 6.8 4.7 10.9 10 4.1 10.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Aconitase PF00330.20 CAR23378.1 - 3.3e-157 524.2 0.0 4e-157 523.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR23378.1 - 8.6e-44 149.0 0.0 1.7e-43 148.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CAR23378.1 - 0.0063 15.3 0.0 0.014 14.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF521) SH3_1 PF00018.28 CAR23379.1 - 1.3e-33 114.4 5.4 3.9e-11 42.4 0.1 4.5 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 CAR23379.1 - 4.5e-32 109.7 0.0 8.2e-32 108.8 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 CAR23379.1 - 9.5e-32 108.6 6.8 5.2e-11 42.2 0.1 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 CAR23379.1 - 4.8e-27 93.4 0.3 4.3e-09 35.9 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain hSH3 PF14603.6 CAR23379.1 - 1.4e-05 25.4 0.0 0.022 15.2 0.0 3.6 2 1 1 3 3 3 1 Helically-extended SH3 domain SAM_4 PF18017.1 CAR23379.1 - 0.0006 19.7 0.0 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF962 PF06127.11 CAR23380.1 - 9.9e-26 89.7 2.3 1.4e-25 89.2 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Proteasome PF00227.26 CAR23381.1 - 4.3e-43 147.0 0.0 6.3e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR23381.1 - 2.3e-15 56.0 0.1 3.7e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rsc14 PF08586.10 CAR23382.1 - 1.5e-35 121.9 0.1 2.7e-35 121.1 0.1 1.4 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit zf-BED PF02892.15 CAR23382.1 - 0.033 14.2 0.3 0.098 12.7 0.3 1.8 1 0 0 1 1 1 0 BED zinc finger DUF900 PF05990.12 CAR23382.1 - 0.16 11.5 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) ERG4_ERG24 PF01222.17 CAR23383.1 - 8.1e-180 598.2 27.0 9.1e-180 598.0 27.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans PF04082.18 CAR23384.1 - 5.8e-24 84.5 0.3 1.5e-23 83.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23384.1 - 1.5e-09 37.8 14.0 3.5e-09 36.6 14.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PUF PF00806.19 CAR23385.1 - 1.8e-66 216.3 10.1 1.8e-09 36.8 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MA3 PF02847.17 CAR23385.1 - 0.015 15.3 0.5 0.044 13.8 0.4 1.8 1 1 0 1 1 1 0 MA3 domain CPL PF08144.11 CAR23385.1 - 0.018 15.4 0.2 2.7 8.4 0.0 3.2 2 2 0 2 2 2 0 CPL (NUC119) domain Oxidored_FMN PF00724.20 CAR23386.1 - 1.2e-139 465.4 0.0 1.4e-139 465.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.20 CAR23387.1 - 8.2e-141 469.2 0.0 9.5e-141 469.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family E1-E2_ATPase PF00122.20 CAR23388.1 - 1e-47 162.0 3.8 5.3e-47 159.7 3.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAR23388.1 - 1.4e-19 71.3 0.6 3.4e-19 70.0 0.1 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAR23388.1 - 7.2e-12 44.8 0.0 1.7e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR23388.1 - 0.002 17.9 0.1 0.0044 16.8 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR23388.1 - 0.0049 16.9 0.0 0.0093 16.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) ADH_N PF08240.12 CAR23389.1 - 1.4e-21 76.4 5.0 2.6e-21 75.5 5.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR23389.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CAR23389.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CAR23389.1 - 0.0065 15.8 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain tRNA_int_endo PF01974.17 CAR23390.1 - 4.7e-16 58.6 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Cation_ATPase_C PF00689.21 CAR23391.1 - 2.1e-45 154.7 8.6 2.1e-45 154.7 8.6 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CAR23391.1 - 3.9e-40 137.3 1.7 3.9e-40 137.3 1.7 2.9 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase PF13246.6 CAR23391.1 - 1.5e-20 73.1 0.0 3.8e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR23391.1 - 3.5e-16 60.1 0.1 1.2e-15 58.3 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAR23391.1 - 7.3e-12 44.8 0.1 2.6e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR23391.1 - 0.00048 19.9 1.6 0.0012 18.7 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 CAR23391.1 - 1.1 8.0 7.0 1.1 7.9 0.3 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MFS_MOT1 PF16983.5 CAR23391.1 - 2.1 8.8 8.9 0.1 13.0 2.4 2.2 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily COG5 PF10392.9 CAR23392.1 - 0.0011 19.2 5.0 0.0018 18.4 1.3 2.4 1 1 2 3 3 3 2 Golgi transport complex subunit 5 DUF1664 PF07889.12 CAR23392.1 - 0.0065 16.5 1.1 0.013 15.6 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF1690 PF07956.11 CAR23392.1 - 0.011 16.1 1.5 0.011 16.1 1.5 1.8 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Laminin_II PF06009.12 CAR23392.1 - 0.015 15.3 2.4 0.027 14.5 2.4 1.5 1 0 0 1 1 1 0 Laminin Domain II Glyco_H_20C_C PF18088.1 CAR23392.1 - 0.02 14.7 1.2 0.044 13.6 1.0 1.5 2 0 0 2 2 2 0 Glycoside Hydrolase 20C C-terminal domain Goodbye PF17109.5 CAR23392.1 - 0.041 14.3 0.2 0.095 13.1 0.2 1.6 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain TSNAXIP1_N PF15739.5 CAR23392.1 - 0.044 14.2 3.8 0.27 11.6 0.2 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus FlaC_arch PF05377.11 CAR23392.1 - 0.079 13.4 3.8 1.1 9.7 2.4 3.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) LRRFIP PF09738.9 CAR23392.1 - 0.084 12.3 2.2 0.12 11.9 2.2 1.2 1 0 0 1 1 1 0 LRRFIP family DUF4208 PF13907.6 CAR23392.1 - 0.12 12.8 2.7 8.2 6.9 0.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) Fib_alpha PF08702.10 CAR23392.1 - 0.29 11.3 4.8 0.58 10.3 4.4 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 CAR23393.1 - 1.3e-14 54.3 9.3 7.4e-07 29.8 0.0 5.3 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23393.1 - 8.3e-08 32.4 0.1 0.13 12.5 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR23393.1 - 0.0061 16.5 0.1 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Rep_fac-A_C PF08646.10 CAR23394.1 - 1.5e-57 193.5 2.4 3.8e-56 188.9 0.6 2.5 2 1 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CAR23394.1 - 4.4e-34 116.3 0.1 8.9e-31 105.7 0.0 3.6 4 0 0 4 4 4 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CAR23394.1 - 3.3e-22 78.3 0.4 1.6e-10 40.9 0.0 4.6 4 0 0 4 4 4 4 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CAR23394.1 - 0.00022 21.0 0.0 0.11 12.2 0.0 3.0 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 Rep-A_N PF04057.12 CAR23394.1 - 0.00027 20.9 0.0 0.00053 20.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain TPP1 PF10341.9 CAR23394.1 - 0.02 14.9 0.1 0.057 13.4 0.0 1.8 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD DUF4539 PF15072.6 CAR23394.1 - 0.13 12.3 0.0 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4539) Fungal_trans PF04082.18 CAR23395.1 - 7.4e-07 28.5 0.1 1.2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23395.1 - 4.1e-05 23.6 8.6 0.0001 22.4 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FNIP_M PF14637.6 CAR23395.1 - 0.072 13.1 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Folliculin-interacting protein middle domain WD40 PF00400.32 CAR23396.1 - 1.3e-19 70.2 7.1 0.0039 18.0 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23396.1 - 1.2e-17 64.0 5.3 1e-09 38.5 0.1 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR23396.1 - 9e-06 25.7 0.2 0.002 18.0 0.1 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR23396.1 - 0.031 13.2 0.1 0.36 9.7 0.0 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CAR23397.1 - 6.5e-10 39.5 4.7 0.00013 22.7 0.3 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23397.1 - 6.3e-05 23.2 0.3 0.022 15.0 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CAR23397.1 - 0.0016 17.1 0.0 0.0025 16.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 CAR23397.1 - 0.012 15.5 0.5 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A EMP24_GP25L PF01105.24 CAR23398.1 - 1.2e-51 175.2 1.5 1.4e-51 175.0 1.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DMRT-like PF15791.5 CAR23399.1 - 0.38 11.2 7.5 0.98 9.9 2.2 3.2 1 1 2 3 3 3 0 Doublesex-and mab-3-related transcription factor C1 and C2 B-block_TFIIIC PF04182.12 CAR23400.1 - 4.1e-14 52.5 0.1 1.4e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC N6-adenineMlase PF10237.9 CAR23401.1 - 1.6e-55 187.3 0.1 1.6e-55 187.3 0.1 1.5 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase 3Beta_HSD PF01073.19 CAR23402.1 - 6e-90 301.0 0.0 7.4e-90 300.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CAR23402.1 - 4.6e-27 95.0 0.0 5.9e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR23402.1 - 3.7e-14 52.9 0.0 1e-13 51.5 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR23402.1 - 3e-11 43.0 0.0 9.4e-10 38.1 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CAR23402.1 - 1.4e-07 30.9 0.0 3.8e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CAR23402.1 - 5.2e-07 29.1 0.0 9.7e-07 28.2 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CAR23402.1 - 1.6e-06 28.1 0.0 2.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CAR23402.1 - 0.0028 17.6 0.0 0.024 14.5 0.0 2.2 1 1 0 1 1 1 1 KR domain Vps8 PF12816.7 CAR23403.1 - 6.3e-45 153.1 1.6 1.2e-44 152.3 0.5 2.0 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_5 PF14634.6 CAR23403.1 - 0.011 15.7 2.7 0.048 13.6 2.7 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR23403.1 - 0.047 13.6 1.3 0.21 11.5 1.3 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAR23403.1 - 0.092 13.1 1.3 0.34 11.2 1.3 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CAR23403.1 - 0.99 9.2 7.8 0.058 13.2 1.7 2.2 2 0 0 2 2 2 0 RING-like zinc finger EF1_GNE PF00736.19 CAR23404.1 - 2.1e-30 104.7 1.1 2.1e-30 104.7 1.1 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CAR23404.1 - 1.8e-13 50.7 6.1 1.8e-13 50.7 6.1 2.7 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 CAR23404.1 - 0.038 14.0 0.1 0.18 11.8 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CAR23404.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF5 PF04855.12 CAR23405.1 - 2.4e-54 184.7 0.5 7.3e-31 107.8 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 PepX_N PF09168.10 CAR23405.1 - 0.13 12.7 0.5 3 8.2 0.1 2.4 1 1 1 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal dCMP_cyt_deam_1 PF00383.23 CAR23406.1 - 3e-10 39.9 0.5 5e-10 39.2 0.5 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR23406.1 - 1e-05 25.3 0.6 2.8e-05 23.9 0.6 1.9 1 1 0 1 1 1 1 MafB19-like deaminase Telomerase_RBD PF12009.8 CAR23407.1 - 2.7e-25 89.0 0.4 9.6e-25 87.2 0.4 2.0 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CAR23407.1 - 3e-06 26.9 2.6 0.0019 17.7 0.2 2.8 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) AIP3 PF03915.13 CAR23408.1 - 3.9e-132 441.2 15.3 3.9e-132 441.2 15.3 2.0 2 0 0 2 2 2 1 Actin interacting protein 3 RE_MjaI PF09568.10 CAR23408.1 - 0.032 14.1 0.4 0.076 12.8 0.4 1.6 1 0 0 1 1 1 0 MjaI restriction endonuclease HSBP1 PF06825.12 CAR23408.1 - 0.079 12.8 0.2 0.48 10.3 0.2 2.4 1 0 0 1 1 1 0 Heat shock factor binding protein 1 T6PP_N PF18572.1 CAR23408.1 - 1.1 9.1 10.7 3.2 7.7 0.1 3.7 3 1 1 4 4 4 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Mus7 PF09462.10 CAR23409.1 - 6e-26 91.5 10.4 8.1e-21 74.5 4.4 2.2 1 1 0 2 2 2 2 Mus7/MMS22 family SANT_DAMP1_like PF16282.5 CAR23410.1 - 6.1e-26 90.4 0.9 6.1e-26 90.4 0.9 2.6 3 0 0 3 3 3 1 SANT/Myb-like domain of DAMP1 DUF2868 PF11067.8 CAR23410.1 - 0.01 15.3 3.9 0.018 14.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Myb_DNA-bind_6 PF13921.6 CAR23410.1 - 0.033 14.4 0.1 0.033 14.4 0.1 2.9 3 0 0 3 3 3 0 Myb-like DNA-binding domain USP8_interact PF08941.10 CAR23410.1 - 0.2 11.5 4.0 0.37 10.6 2.8 2.1 2 0 0 2 2 2 0 USP8 interacting UPF0449 PF15136.6 CAR23410.1 - 0.81 10.2 11.9 6.8 7.2 0.2 3.0 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Cullin PF00888.22 CAR23411.1 - 8.8e-149 497.0 9.0 8.8e-149 497.0 9.0 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CAR23411.1 - 2e-17 62.9 0.0 6.6e-17 61.3 0.0 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-CCCH PF00642.24 CAR23412.1 - 1.9e-09 37.2 3.0 1.9e-09 37.2 3.0 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.6 CAR23412.1 - 1e-07 31.6 10.6 3e-07 30.2 10.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR23412.1 - 1.8e-07 30.9 7.0 1.8e-07 30.9 7.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR23412.1 - 1.6e-06 28.0 10.4 1.6e-06 28.0 10.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR23412.1 - 3.1e-06 27.0 11.8 7.9e-06 25.7 11.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR23412.1 - 3.2e-06 27.1 5.1 3.9e-06 26.8 3.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf_CCCH_4 PF18345.1 CAR23412.1 - 4.5e-06 26.5 5.7 4.5e-06 26.5 5.7 2.1 2 0 0 2 2 2 1 Zinc finger domain Prok-RING_4 PF14447.6 CAR23412.1 - 5.8e-05 22.9 7.6 0.00012 21.9 5.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAR23412.1 - 0.00015 22.1 8.8 0.00047 20.4 8.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 CAR23412.1 - 0.00048 20.2 5.1 0.00048 20.2 5.1 2.2 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 CAR23412.1 - 0.00053 19.7 1.9 0.00053 19.7 1.9 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CAR23412.1 - 0.012 16.0 0.9 0.012 16.0 0.9 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 CAR23412.1 - 0.038 14.1 8.4 0.038 14.1 8.4 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CAR23412.1 - 0.16 11.8 7.3 0.4 10.6 7.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CAR23412.1 - 0.37 11.1 6.0 1.1 9.6 6.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Pex24p PF06398.11 CAR23413.1 - 3.9e-97 325.5 6.5 5e-97 325.1 6.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ribosomal_L38e PF01781.18 CAR23414.1 - 3.2e-29 100.8 2.4 3.6e-29 100.7 2.4 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta_N PF17683.1 CAR23415.1 - 8.3e-36 123.6 7.8 2.3e-35 122.2 7.8 1.8 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 CAR23415.1 - 2.6e-28 98.0 1.0 4.7e-28 97.1 1.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Adeno_E1B_19K PF01691.16 CAR23415.1 - 0.014 14.9 0.1 0.039 13.5 0.0 1.7 2 0 0 2 2 2 0 Adenovirus E1B 19K protein / small t-antigen Tau95 PF09734.9 CAR23415.1 - 0.017 15.9 10.7 5.2 7.9 10.4 2.6 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Peptidase_S30 PF01577.16 CAR23415.1 - 0.06 13.0 7.1 0.13 11.9 7.1 1.5 1 0 0 1 1 1 0 Potyvirus P1 protease Prp18 PF02840.15 CAR23416.1 - 1e-38 132.6 0.5 2.3e-38 131.5 0.1 1.8 2 0 0 2 2 2 1 Prp18 domain NYD-SP28_assoc PF14775.6 CAR23416.1 - 0.04 14.0 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Sperm tail C-terminal domain RXLR PF16810.5 CAR23416.1 - 1.2 9.5 4.5 2.7 8.4 4.5 1.7 1 1 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity DUF4112 PF13430.6 CAR23417.1 - 5.9e-26 90.8 0.4 7.7e-26 90.4 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTP_transf_like PF01467.26 CAR23418.1 - 4.9e-28 98.1 0.0 4.3e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CAR23418.1 - 0.04 13.8 2.2 20 5.0 0.1 3.2 3 0 0 3 3 3 0 FAD synthetase HABP4_PAI-RBP1 PF04774.15 CAR23419.1 - 0.0048 17.7 0.7 0.0055 17.5 0.3 1.4 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family CTP_transf_like PF01467.26 CAR23420.1 - 1.5e-32 112.7 0.0 2.3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Fungal_trans PF04082.18 CAR23421.1 - 3.7e-25 88.5 2.7 5.8e-25 87.8 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23421.1 - 9.3e-07 28.9 9.0 1.6e-06 28.1 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.25 CAR23422.1 - 1.2e-65 221.8 0.2 1.8e-65 221.3 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PWI PF01480.17 CAR23423.1 - 3.6e-05 24.0 0.5 0.00017 21.9 0.5 2.0 2 0 0 2 2 2 1 PWI domain Xpo1 PF08389.12 CAR23423.1 - 0.19 11.8 1.3 0.93 9.5 0.1 2.4 2 0 0 2 2 2 0 Exportin 1-like protein DUF2868 PF11067.8 CAR23423.1 - 0.21 11.0 3.1 2.7 7.4 1.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2868) Gon7 PF08738.10 CAR23423.1 - 0.45 10.6 4.1 0.99 9.5 0.6 3.2 3 1 0 3 3 3 0 Gon7 family PspB PF06667.12 CAR23423.1 - 1.4 9.0 5.4 11 6.1 1.0 3.5 3 0 0 3 3 3 0 Phage shock protein B Abhydrolase_1 PF00561.20 CAR23425.1 - 8.3e-20 71.5 0.0 3.7e-19 69.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR23425.1 - 6e-12 46.6 0.0 9.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR23425.1 - 4.5e-09 35.9 0.0 7.9e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CAR23425.1 - 3.3e-05 24.1 0.0 5.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 CAR23425.1 - 0.0003 20.6 0.0 0.037 13.7 0.0 2.4 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CAR23425.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CAR23425.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Torsin PF06309.11 CAR23425.1 - 0.094 12.8 0.1 0.48 10.5 0.0 2.1 2 0 0 2 2 2 0 Torsin FSH1 PF03959.13 CAR23425.1 - 0.12 12.0 0.2 14 5.2 0.1 3.0 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 CAR23425.1 - 0.22 11.1 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase zf-C3HC4_3 PF13920.6 CAR23427.1 - 3.5e-09 36.4 11.8 7.3e-09 35.4 11.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR23427.1 - 0.062 13.2 10.4 0.12 12.3 10.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AICARFT_IMPCHas PF01808.18 CAR23429.1 - 1e-93 314.1 0.0 1.7e-93 313.3 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CAR23429.1 - 1.1e-25 89.6 0.3 4.7e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 MGS-like domain Ribosomal_L15e PF00827.17 CAR23430.1 - 2.1e-88 295.1 11.6 2.6e-88 294.8 11.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Plasmodium_Vir PF05795.11 CAR23432.1 - 0.95 8.8 4.8 1 8.7 4.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DAG_kinase_N PF14513.6 CAR23432.1 - 2.6 8.2 9.6 4.8 7.4 9.6 1.4 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Macoilin PF09726.9 CAR23432.1 - 3.2 6.2 22.7 4.2 5.8 22.7 1.2 1 0 0 1 1 1 0 Macoilin family RIFIN PF02009.16 CAR23432.1 - 4 7.2 4.6 4.7 7.0 4.6 1.1 1 0 0 1 1 1 0 Rifin DUF572 PF04502.13 CAR23432.1 - 8 6.0 7.6 8.9 5.8 7.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pkr1 PF08636.10 CAR23433.1 - 1.4e-29 102.1 10.8 1.7e-29 101.8 10.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4834 PF16118.5 CAR23433.1 - 0.093 13.7 0.1 0.13 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Yop-YscD_ppl PF16693.5 CAR23434.1 - 0.045 13.2 0.7 0.076 12.4 0.7 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain MIF4G_like PF09088.11 CAR23435.1 - 4.7e-55 186.3 0.6 1e-54 185.2 0.6 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 CAR23435.1 - 2.2e-48 165.1 1.4 4.6e-47 160.7 1.4 2.4 1 1 0 1 1 1 1 MIF4G like MIF4G PF02854.19 CAR23435.1 - 2.8e-13 50.0 1.7 2.8e-13 50.0 1.7 2.1 3 0 0 3 3 3 1 MIF4G domain Pox_polyA_pol_N PF12630.7 CAR23435.1 - 0.022 15.1 0.1 0.022 15.1 0.1 2.7 4 0 0 4 4 4 0 Poxvirus poly(A) polymerase N-terminal domain DUF4129 PF13559.6 CAR23436.1 - 0.11 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) SNF2_N PF00176.23 CAR23437.1 - 1.7e-69 234.2 0.2 2.8e-69 233.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CAR23437.1 - 7e-16 57.9 0.0 1.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 CAR23437.1 - 7.9e-13 48.7 0.0 3e-12 46.9 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 CAR23437.1 - 1e-08 34.9 9.4 1.8e-08 34.1 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR23437.1 - 1.7e-07 31.2 6.1 3.5e-07 30.1 6.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CAR23437.1 - 1.7e-07 31.0 7.2 2.9e-07 30.2 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR23437.1 - 2.2e-07 31.1 8.2 4.9e-07 30.0 8.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CAR23437.1 - 2.6e-07 30.5 8.6 4.7e-07 29.7 8.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 CAR23437.1 - 4.7e-06 26.7 0.0 2e-05 24.7 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 CAR23437.1 - 0.00047 19.9 7.7 0.00099 18.9 7.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAR23437.1 - 0.0012 18.9 0.2 0.0022 18.0 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CAR23437.1 - 0.0069 16.7 4.4 0.014 15.7 4.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CAR23437.1 - 0.012 15.7 8.7 0.029 14.5 8.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CAR23437.1 - 0.013 15.3 6.3 0.025 14.4 6.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CAR23437.1 - 0.015 15.1 6.8 0.036 13.9 6.8 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CAR23437.1 - 0.14 11.9 7.4 0.36 10.6 7.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 CAR23437.1 - 0.15 11.8 6.6 0.3 10.9 6.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CAR23437.1 - 0.48 10.6 3.7 1 9.6 3.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 CAR23437.1 - 0.58 10.4 6.0 1.2 9.4 6.0 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain MOZ_SAS PF01853.18 CAR23438.1 - 1.3e-55 187.8 0.0 1.8e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CAR23438.1 - 1.4e-06 27.8 3.5 4.5e-06 26.2 3.5 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CAR23438.1 - 0.00023 21.5 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR23438.1 - 0.037 14.3 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR23438.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4590 PF15257.6 CAR23438.1 - 0.17 11.8 2.8 0.28 11.1 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) HA2 PF04408.23 CAR23439.1 - 7.8e-28 96.9 0.0 7.8e-28 96.9 0.0 2.5 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAR23439.1 - 3.8e-12 46.5 0.0 1.3e-10 41.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CAR23439.1 - 1.8e-11 44.2 0.0 5.5e-11 42.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CAR23439.1 - 5.6e-08 32.8 0.1 1.7e-07 31.2 0.1 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR23439.1 - 2.7e-06 27.7 0.5 3.2e-05 24.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain HTH_37 PF13744.6 CAR23439.1 - 0.00057 19.8 1.0 0.0061 16.5 0.2 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain ATPase PF06745.13 CAR23439.1 - 0.0031 16.9 0.9 0.0081 15.5 0.0 2.1 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.6 CAR23439.1 - 0.0066 16.8 0.0 0.02 15.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CAR23439.1 - 0.016 15.0 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CAR23439.1 - 0.018 14.5 0.0 0.095 12.1 0.0 2.2 3 0 0 3 3 3 0 PhoH-like protein TsaE PF02367.17 CAR23439.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CAR23439.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CAR23439.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.2 3 1 0 3 3 2 0 ABC transporter Bromodomain PF00439.25 CAR23440.1 - 0.0032 17.5 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 Bromodomain Nramp PF01566.18 CAR23441.1 - 2.7e-97 326.0 18.1 4e-97 325.4 18.1 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein E1-E2_ATPase PF00122.20 CAR23441.1 - 8.6 5.8 11.7 0.089 12.3 2.1 2.6 2 1 1 3 3 3 0 E1-E2 ATPase Y_Y_Y PF07495.13 CAR23442.1 - 0.0041 17.0 1.4 1.1 9.3 0.5 2.9 2 0 0 2 2 2 2 Y_Y_Y domain Hydrolase PF00702.26 CAR23443.1 - 1.8e-07 31.7 0.0 3.5e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR23443.1 - 2.8e-07 30.8 0.0 6.1e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR23443.1 - 0.00065 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Anti-TRAP PF15777.5 CAR23443.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein CAAP1 PF15335.6 CAR23443.1 - 0.11 13.1 0.0 0.29 11.7 0.0 1.7 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 COX6B PF02297.17 CAR23444.1 - 3.1e-20 72.2 3.7 3.7e-20 71.9 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb RIC1 PF07064.13 CAR23445.1 - 3.6e-19 69.2 0.0 1e-18 67.7 0.0 1.8 1 1 0 1 1 1 1 RIC1 mRNA_stabil PF13929.6 CAR23445.1 - 0.0038 16.3 0.4 0.069 12.1 0.1 2.5 2 0 0 2 2 2 1 mRNA stabilisation CAF1C_H4-bd PF12265.8 CAR23446.1 - 1.5e-15 57.2 0.0 3.8e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CAR23446.1 - 1.8e-10 41.2 10.5 0.0026 18.5 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23446.1 - 1.5e-05 25.2 0.5 0.24 11.7 0.0 3.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain NFACT-R_1 PF05670.13 CAR23447.1 - 3e-33 114.7 0.1 8.3e-33 113.3 0.0 1.7 2 0 0 2 2 2 1 NFACT protein RNA binding domain HisK_sensor PF18698.1 CAR23447.1 - 0.044 14.1 0.6 0.24 11.8 1.3 1.7 2 0 0 2 2 2 0 Histidine kinase sensor domain Meiotic_rec114 PF03525.14 CAR23448.1 - 0.0019 17.2 9.8 0.0077 15.2 9.8 1.9 1 1 0 1 1 1 1 Meiotic recombination protein rec114 CLTH PF10607.9 CAR23451.1 - 1.3e-29 103.0 2.6 7.5e-29 100.5 2.1 2.0 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.27 CAR23453.1 - 4.3e-14 51.8 2.4 7.7e-14 51.0 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger TetR_C_2 PF08361.11 CAR23453.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region DRMBL PF07522.14 CAR23454.1 - 1.1e-25 90.0 0.3 2.1e-25 89.0 0.3 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CAR23454.1 - 0.0041 16.6 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Arf PF00025.21 CAR23455.1 - 3.7e-44 150.2 0.0 4.5e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAR23455.1 - 7e-12 45.2 0.2 4e-07 29.5 0.1 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAR23455.1 - 7.1e-11 41.9 0.0 8.6e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CAR23455.1 - 2.3e-08 34.3 0.0 3.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAR23455.1 - 1.3e-06 28.1 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CAR23455.1 - 4.4e-05 23.5 0.0 6.3e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR23455.1 - 0.00043 19.8 0.1 0.00092 18.8 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CAR23455.1 - 0.0014 18.1 0.0 0.0018 17.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CAR23455.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ldh_1_N PF00056.23 CAR23456.1 - 2.6e-45 154.0 0.1 4.3e-45 153.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAR23456.1 - 1.6e-41 142.0 0.0 2.5e-41 141.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CAR23456.1 - 0.00025 20.1 0.0 0.00037 19.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.25 CAR23458.1 - 3.8e-65 219.9 0.0 4.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23458.1 - 1.2e-27 96.8 0.0 1.9e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR23458.1 - 6.4e-05 23.0 0.8 0.0055 16.7 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR23458.1 - 0.00083 19.0 0.1 0.0013 18.3 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CAR23458.1 - 0.001 18.5 0.0 0.049 12.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like WHIM1 PF15612.6 CAR23458.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 Kdo PF06293.14 CAR23458.1 - 0.023 14.0 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAR23458.1 - 0.061 12.3 0.1 0.083 11.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Epimerase PF01370.21 CAR23459.1 - 3.8e-15 56.0 0.0 5.3e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR23459.1 - 2.6e-10 39.8 0.0 3.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CAR23459.1 - 7.9e-09 35.3 0.3 1.5e-08 34.4 0.1 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CAR23459.1 - 4.4e-08 33.2 0.0 1.4e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 CAR23459.1 - 4.5e-07 29.3 0.1 4.2e-06 26.1 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CAR23459.1 - 4.5e-05 23.4 0.0 9.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CAR23459.1 - 0.00014 21.4 0.0 0.00051 19.6 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase TPP_enzyme_N PF02776.18 CAR23460.1 - 5.1e-28 97.8 0.0 1.1e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR23460.1 - 5.6e-22 78.0 0.0 1.2e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR23460.1 - 1.5e-15 57.3 0.0 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 CAR23460.1 - 0.042 12.8 0.0 0.095 11.6 0.0 1.5 1 1 1 2 2 2 0 Dehydrogenase E1 component zf-C2H2 PF00096.26 CAR23461.1 - 6.3e-20 70.4 32.4 1.8e-05 24.9 0.5 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR23461.1 - 1.8e-19 69.2 28.0 1.5e-08 34.7 1.1 4.4 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR23461.1 - 5.5e-12 45.5 28.4 0.00077 20.1 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger COPI_C PF06957.11 CAR23461.1 - 0.039 12.7 1.2 1.4 7.6 0.2 2.2 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus zf-C2H2_aberr PF17017.5 CAR23461.1 - 0.071 13.2 0.1 0.071 13.2 0.1 1.6 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 CAR23461.1 - 0.074 13.1 26.9 0.083 12.9 0.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CAR23461.1 - 0.18 11.6 13.0 1.1 9.1 0.3 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 CAR23461.1 - 0.29 11.4 9.7 1.8 8.9 0.3 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CAR23461.1 - 0.33 11.4 15.2 17 6.0 0.7 4.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type DZR PF12773.7 CAR23461.1 - 0.63 10.1 6.8 4.3 7.4 6.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF3268 PF11672.8 CAR23461.1 - 3.1 8.1 5.7 0.48 10.8 0.7 2.2 3 0 0 3 3 2 0 zinc-finger-containing domain zf_UBZ PF18439.1 CAR23461.1 - 4.7 6.9 8.4 9.1 6.0 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF1804 PF08822.11 CAR23462.1 - 0.0013 18.8 0.3 0.0021 18.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) DIPSY PF11763.8 CAR23462.1 - 0.041 14.1 0.0 0.067 13.4 0.0 1.3 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal Pox_D5 PF03288.16 CAR23462.1 - 0.29 11.6 2.2 0.53 10.8 0.8 2.1 2 0 0 2 2 2 0 Poxvirus D5 protein-like TRAPP PF04051.16 CAR23463.1 - 7.9e-34 116.5 0.0 1.2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF5393 PF17371.2 CAR23463.1 - 0.1 10.7 0.0 0.17 10.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) SH3_9 PF14604.6 CAR23464.1 - 2.9e-25 87.9 0.2 3.1e-14 52.5 0.1 3.5 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 CAR23464.1 - 1.4e-23 82.2 0.1 4.9e-13 48.5 0.1 2.9 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 CAR23464.1 - 1.6e-19 69.9 0.4 1.6e-19 69.9 0.4 2.5 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CAR23464.1 - 7.8e-16 57.5 0.0 1.5e-11 43.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 CAR23464.1 - 0.0063 16.6 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 1 SH3 domain DUF2417 PF10329.9 CAR23465.1 - 1.8e-78 263.2 4.5 2.5e-78 262.8 4.5 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 CAR23465.1 - 2.2e-09 37.3 0.3 8.7e-09 35.4 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CAR23465.1 - 0.13 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain FHA PF00498.26 CAR23466.1 - 4.1e-15 55.9 0.1 7.5e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CAR23466.1 - 3.7e-12 45.8 7.3 7.1e-12 44.8 7.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CAR23466.1 - 2.4e-07 31.0 10.5 4.1e-07 30.2 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CAR23466.1 - 0.00059 19.7 8.4 0.00093 19.1 8.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR23466.1 - 0.001 18.9 10.4 0.0017 18.2 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 CAR23466.1 - 0.0011 19.3 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 CAR23466.1 - 0.0012 19.1 6.2 0.0022 18.2 6.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR23466.1 - 0.01 15.9 4.3 0.019 15.0 4.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CAR23466.1 - 0.013 15.3 10.3 0.021 14.6 10.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR23466.1 - 0.015 15.2 10.1 0.025 14.4 10.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.14 CAR23466.1 - 0.021 14.3 0.6 0.044 13.3 0.2 1.7 2 0 0 2 2 2 0 SecD/SecF GG Motif zf-HC5HC2H PF13771.6 CAR23466.1 - 0.072 13.3 2.9 0.14 12.4 2.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.6 CAR23466.1 - 0.24 11.5 8.9 0.47 10.5 8.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.11 CAR23466.1 - 3.8 7.9 6.4 7.6 6.9 6.4 1.6 1 1 0 1 1 1 0 RING-like domain Malate_synthase PF01274.22 CAR23467.1 - 4.7e-217 721.4 0.0 6.1e-217 721.0 0.0 1.1 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 CAR23467.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Aminotran_3 PF00202.21 CAR23468.1 - 1.1e-111 373.4 0.0 1.4e-111 373.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III TMEM52 PF14979.6 CAR23468.1 - 0.0065 16.4 0.4 0.01 15.7 0.4 1.2 1 0 0 1 1 1 1 Transmembrane 52 PhyH PF05721.13 CAR23469.1 - 4e-29 102.4 0.1 5.2e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) CX9C PF16860.5 CAR23469.1 - 0.057 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, zf-C2H2 PF00096.26 CAR23470.1 - 2.1e-06 27.9 9.8 0.0011 19.2 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR23470.1 - 9.3e-05 23.0 9.3 0.052 14.4 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR23470.1 - 0.00032 21.0 4.3 0.00032 21.0 4.3 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-MYST PF17772.1 CAR23470.1 - 0.12 12.0 0.0 0.37 10.4 0.0 1.8 1 0 0 1 1 1 0 MYST family zinc finger domain Rad9_Rad53_bind PF08605.10 CAR23471.1 - 5.4e-37 126.9 0.0 9.7e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 CAR23471.1 - 8.6e-07 29.3 1.1 1.6e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CAR23471.1 - 0.03 14.7 0.1 0.083 13.3 0.1 1.8 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Nucleo_P87 PF07267.11 CAR23473.1 - 0.01 14.7 0.4 0.015 14.2 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box PF00646.33 CAR23474.1 - 3.5e-08 33.1 0.3 7.2e-08 32.1 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CAR23474.1 - 1.7e-06 27.8 0.1 3.6e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CAR23474.1 - 0.0059 16.5 0.2 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 F-box NAD_binding_10 PF13460.6 CAR23475.1 - 3.6e-21 75.9 0.0 4.6e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CAR23475.1 - 1.7e-15 57.3 0.1 1.6e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 CAR23475.1 - 2.4e-07 30.5 0.1 0.00029 20.4 0.0 2.6 2 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CAR23475.1 - 0.00034 20.9 0.0 0.00062 20.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 CAR23475.1 - 0.0088 15.5 0.0 3.1 7.1 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CAR23475.1 - 0.01 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 CAR23475.1 - 0.013 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain PRKCSH-like PF12999.7 CAR23476.1 - 5.1e-41 140.4 8.6 5.1e-41 140.4 8.6 2.3 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CAR23476.1 - 8.4e-21 74.3 0.1 1.7e-19 70.1 0.1 2.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CAR23476.1 - 0.00019 22.3 0.0 0.00075 20.4 0.0 2.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein HAUS-augmin3 PF14932.6 CAR23476.1 - 0.0044 16.6 0.6 0.0044 16.6 0.6 2.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 Vta1 PF04652.16 CAR23476.1 - 0.19 11.7 8.7 0.48 10.4 0.6 3.1 3 0 0 3 3 3 0 Vta1 like DUF4776 PF16003.5 CAR23476.1 - 0.22 10.5 3.2 0.4 9.6 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF727 PF05303.12 CAR23476.1 - 0.38 10.8 6.3 8.6 6.5 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF727) DUF2206 PF09971.9 CAR23476.1 - 0.55 8.9 1.5 0.62 8.8 0.3 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) Retrotrans_gag PF03732.17 CAR23476.1 - 0.7 10.2 4.6 11 6.4 0.3 3.3 3 0 0 3 3 2 0 Retrotransposon gag protein Tup_N PF08581.10 CAR23476.1 - 1.2 9.5 5.4 1.3 9.4 0.1 3.3 2 1 1 3 3 3 0 Tup N-terminal MBR1 PF17058.5 CAR23476.1 - 6.3 7.0 12.8 0.64 10.3 7.5 2.2 2 1 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 Phage_GP20 PF06810.11 CAR23476.1 - 7 6.4 10.0 1.8 8.4 0.3 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 Svf1_C PF17187.4 CAR23477.1 - 1.6e-39 135.3 0.0 2.5e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CAR23477.1 - 1e-34 120.0 0.1 1.6e-34 119.3 0.1 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain CRF1 PF10380.9 CAR23478.1 - 1.1e-33 115.9 1.3 1.1e-33 115.9 1.3 3.4 3 1 0 3 3 3 1 Transcription factor CRF1 Utp13 PF08625.11 CAR23479.1 - 1.4e-46 157.9 0.4 2.4e-46 157.2 0.4 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 CAR23479.1 - 1e-41 140.1 24.9 2.8e-06 27.9 0.0 11.0 10 1 1 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23479.1 - 7.3e-19 67.9 5.2 0.00012 22.3 0.3 6.5 5 2 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR23479.1 - 6e-11 42.2 2.7 1.9e-05 24.2 0.1 4.5 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 CAR23479.1 - 4.5e-05 22.3 9.3 0.36 9.4 0.3 5.6 4 1 1 6 6 6 3 Nucleoporin Nup120/160 Hira PF07569.11 CAR23479.1 - 0.0092 15.7 0.0 3.3 7.4 0.0 3.5 3 0 0 3 3 3 1 TUP1-like enhancer of split Rsa3 PF14615.6 CAR23480.1 - 3.4e-18 64.9 0.0 6.1e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 IMUP PF15761.5 CAR23480.1 - 0.032 14.9 6.9 0.048 14.3 6.9 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CAR23480.1 - 8.3 5.9 18.3 11 5.6 18.3 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein VIT1 PF01988.19 CAR23481.1 - 4.8e-61 206.4 0.2 6.5e-61 205.9 0.2 1.2 1 0 0 1 1 1 1 VIT family Histone PF00125.24 CAR23482.1 - 4.3e-20 72.4 4.6 5.3e-20 72.1 4.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR23482.1 - 7.4e-06 26.2 0.1 7.4e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CAR23482.1 - 0.002 18.6 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CAR23482.1 - 0.0069 16.6 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein YscO-like PF16789.5 CAR23482.1 - 0.058 13.4 0.6 0.071 13.2 0.6 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 CAR23483.1 - 1.5e-20 72.6 2.0 2.4e-20 72.0 2.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAR23483.1 - 2.8e-17 63.3 0.0 3.6e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR23483.1 - 1.3e-05 25.3 0.0 1.9e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RAP1 PF07218.11 CAR23484.1 - 6.3 4.9 8.3 11 4.2 8.3 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ADK PF00406.22 CAR23485.1 - 5.7e-59 198.5 0.0 6.8e-59 198.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAR23485.1 - 5.2e-21 75.5 0.1 1e-20 74.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CAR23485.1 - 1.1e-17 63.7 0.0 2.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CAR23485.1 - 1.9e-05 24.8 0.0 4.4e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR23485.1 - 2.7e-05 24.7 0.0 6.9e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CAR23485.1 - 0.053 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CAR23485.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 CAR23485.1 - 0.15 12.3 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SIR4_SID PF16991.5 CAR23486.1 - 2.8e-22 79.5 0.1 2.8e-22 79.5 0.1 3.9 5 1 0 5 5 5 1 Sir4 SID domain CFIA_Pcf11 PF11526.8 CAR23487.1 - 2.5e-26 92.0 3.4 2.5e-26 92.0 3.4 2.3 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 CAR23487.1 - 0.00025 20.9 0.7 0.00092 19.1 0.0 2.3 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.13 CAR23487.1 - 0.00089 20.0 0.1 0.0056 17.5 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Spore_II_R PF09551.10 CAR23487.1 - 0.057 13.9 5.8 0.14 12.6 4.6 2.2 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Totivirus_coat PF05518.11 CAR23487.1 - 3.9 5.4 8.0 6.2 4.7 8.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein LIM PF00412.22 CAR23487.1 - 4.1 7.7 8.8 5.4 7.3 0.3 2.9 3 0 0 3 3 3 0 LIM domain zf-C2H2_6 PF13912.6 CAR23487.1 - 4.2 7.5 5.4 1.7 8.7 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 CAR23487.1 - 4.8 6.9 9.6 1.8 8.2 4.2 2.9 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Mito_carr PF00153.27 CAR23488.1 - 4.6e-29 100.2 0.3 5e-14 52.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-bind_4 PF13837.6 CAR23489.1 - 0.0021 18.4 0.0 0.0072 16.7 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF573 PF04504.14 CAR23489.1 - 0.0052 17.4 0.0 0.064 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF573 Myb_DNA-bind_6 PF13921.6 CAR23489.1 - 0.07 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Excalibur PF05901.11 CAR23489.1 - 0.13 12.9 0.2 0.3 11.7 0.2 1.6 1 0 0 1 1 1 0 Excalibur calcium-binding domain Myb_DNA-binding PF00249.31 CAR23489.1 - 0.22 11.7 0.0 0.49 10.6 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Sugar_tr PF00083.24 CAR23491.1 - 8.1e-101 338.1 15.4 9.8e-101 337.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR23491.1 - 4.4e-28 98.2 21.5 1.3e-27 96.7 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CAR23491.1 - 0.00045 18.9 17.5 0.0016 17.1 1.0 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 CAR23491.1 - 2.7 6.1 7.6 0.082 11.2 0.9 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_4 PF02390.17 CAR23492.1 - 3.4e-60 202.4 0.1 4.7e-60 202.0 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CAR23492.1 - 0.00029 21.5 0.0 0.0023 18.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR23492.1 - 0.0046 17.7 0.2 0.015 16.0 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 CAR23492.1 - 0.0053 16.3 0.2 0.025 14.1 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CAR23492.1 - 0.032 13.6 0.0 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CAR23492.1 - 0.035 13.9 0.1 0.066 13.0 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L10 PF00466.20 CAR23493.1 - 5.8e-09 36.0 0.0 9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 GHL5 PF14872.6 CAR23494.1 - 0.52 8.3 3.2 0.76 7.7 3.2 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 DUF3767 PF12597.8 CAR23495.1 - 6.5e-38 128.6 0.1 8.5e-38 128.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) CPP1-like PF11833.8 CAR23495.1 - 0.062 12.9 0.6 0.093 12.4 0.6 1.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like YrhK PF14145.6 CAR23495.1 - 0.11 12.3 0.4 0.19 11.6 0.4 1.3 1 0 0 1 1 1 0 YrhK-like protein Sel1 PF08238.12 CAR23496.1 - 1.7e-29 101.6 41.3 2.2e-05 25.0 1.0 8.2 7 2 0 7 7 7 7 Sel1 repeat SOG2 PF10428.9 CAR23496.1 - 8.1 5.5 8.3 16 4.5 8.3 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Aminotran_1_2 PF00155.21 CAR23497.1 - 1.5e-74 251.4 0.4 2e-74 251.0 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CAR23497.1 - 2.8e-08 32.7 0.0 4.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAR23497.1 - 2.4e-05 23.5 0.1 9.9e-05 21.5 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Preseq_ALAS PF09029.10 CAR23497.1 - 0.0043 17.5 3.4 0.014 15.9 3.4 1.8 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence DegT_DnrJ_EryC1 PF01041.17 CAR23497.1 - 0.022 14.1 0.7 0.33 10.2 0.7 2.3 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MYO10_CC PF16735.5 CAR23497.1 - 0.1 12.7 0.0 9.7 6.4 0.0 3.0 2 1 1 3 3 3 0 Unconventional myosin-X coiled coil domain Reticulon PF02453.17 CAR23498.1 - 2.1e-33 115.5 1.3 3e-33 115.0 1.3 1.2 1 0 0 1 1 1 1 Reticulon Aconitase PF00330.20 CAR23499.1 - 2.3e-112 376.4 0.2 2.2e-111 373.1 0.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR23499.1 - 4.5e-33 114.4 0.0 1e-32 113.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Porphobil_deam PF01379.20 CAR23500.1 - 3.4e-72 242.2 0.0 4.8e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CAR23500.1 - 3.7e-23 81.7 0.5 6.8e-23 80.8 0.5 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain TPR_14 PF13428.6 CAR23501.1 - 0.014 16.2 0.0 1.5 9.9 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat Na_Ca_ex PF01699.24 CAR23502.1 - 1.9e-49 167.5 35.9 5.6e-29 101.0 5.8 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Flavokinase PF01687.17 CAR23503.1 - 2.9e-25 88.7 0.0 3.5e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase GLE1 PF07817.13 CAR23504.1 - 1.6e-90 302.7 0.2 3e-90 301.8 0.2 1.5 1 0 0 1 1 1 1 GLE1-like protein Caldesmon PF02029.15 CAR23504.1 - 0.13 11.1 36.6 0.21 10.3 36.6 1.3 1 0 0 1 1 1 0 Caldesmon DUF5401 PF17380.2 CAR23504.1 - 0.36 8.9 34.5 0.47 8.5 34.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4407 PF14362.6 CAR23504.1 - 1.9 7.8 14.6 3.2 7.0 14.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Asp-B-Hydro_N PF05279.11 CAR23504.1 - 4.6 7.2 21.9 7.2 6.6 21.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Presenilin PF01080.17 CAR23504.1 - 8.5 5.0 14.4 12 4.5 14.4 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_L5_C PF00673.21 CAR23505.1 - 3e-27 94.6 0.0 7.1e-27 93.4 0.0 1.6 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CAR23505.1 - 6.2e-13 48.9 0.0 1.6e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 Adaptin_N PF01602.20 CAR23506.1 - 7.9e-104 348.1 8.8 1.1e-103 347.5 8.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CAR23506.1 - 1.1e-53 180.6 0.0 3.5e-53 179.0 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CAR23506.1 - 1.1e-52 177.7 0.4 2.5e-52 176.5 0.4 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Cnd1 PF12717.7 CAR23506.1 - 7.9e-08 32.5 5.0 1.5e-05 25.1 0.3 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR23506.1 - 7.5e-05 23.0 6.0 0.077 13.4 0.0 4.5 1 1 4 5 5 5 3 HEAT repeats Trans_coact PF16805.5 CAR23506.1 - 0.0041 17.2 0.1 0.016 15.3 0.1 2.0 1 0 0 1 1 1 1 Phage late-transcription coactivator DUF5578 PF17741.1 CAR23506.1 - 0.016 14.6 6.1 0.19 11.1 0.5 2.8 2 1 1 3 3 3 0 Family of unknown function (DUF5578) Vac14_Fab1_bd PF12755.7 CAR23506.1 - 0.058 14.0 2.1 0.91 10.2 0.2 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Alpha_adaptinC2 PF02883.20 CAR23506.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain Golgin_A5 PF09787.9 CAR23507.1 - 2.7 7.4 10.1 0.12 11.8 2.1 2.3 3 0 0 3 3 3 0 Golgin subfamily A member 5 Ribosomal_L7Ae PF01248.26 CAR23509.1 - 5.5e-27 93.4 0.2 7.7e-27 92.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hexokinase_1 PF00349.21 CAR23509.1 - 0.088 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Hexokinase Citrate_synt PF00285.21 CAR23509.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Metallophos PF00149.28 CAR23510.1 - 1.4e-14 55.1 0.6 2.5e-14 54.3 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CAR23510.1 - 0.016 15.4 0.0 0.046 13.9 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Torus PF16131.5 CAR23511.1 - 8.2e-34 116.6 0.0 2.1e-33 115.3 0.0 1.7 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 CAR23511.1 - 5.7e-07 29.3 0.1 3.5e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 CAR23511.1 - 2.5 8.0 12.1 5.3 7.0 12.1 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger DEAD PF00270.29 CAR23512.1 - 1.9e-48 164.6 0.1 1.1e-47 162.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR23512.1 - 3.2e-30 104.7 0.1 5.6e-29 100.7 0.1 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR23512.1 - 7.1e-05 22.9 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CAR23512.1 - 0.042 13.2 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit FA_desaturase PF00487.24 CAR23513.1 - 4.9e-22 79.0 20.2 8.1e-22 78.3 20.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CAR23513.1 - 9.9e-06 25.8 0.0 2.5e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TPR_1 PF00515.28 CAR23514.1 - 2.3e-23 81.0 1.8 3e-07 30.0 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAR23514.1 - 2.1e-20 71.1 2.8 5.3e-06 26.1 0.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR23514.1 - 2.3e-16 59.2 0.0 4.5e-07 29.4 0.0 3.9 3 1 1 4 4 3 3 TPR repeat TPR_8 PF13181.6 CAR23514.1 - 2.3e-15 55.5 1.9 7.8e-05 22.6 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR23514.1 - 2.4e-15 55.9 1.7 0.00096 19.8 0.1 5.8 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 CAR23514.1 - 1.4e-12 47.1 1.0 0.087 13.2 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAR23514.1 - 2e-12 47.5 0.1 4.3e-06 27.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR23514.1 - 2.9e-12 46.9 1.2 0.00079 19.9 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CAR23514.1 - 1.6e-09 37.7 0.3 0.00074 19.6 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAR23514.1 - 1.9e-07 30.6 0.3 0.24 11.5 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 CAR23514.1 - 2.6e-07 30.9 1.9 0.15 12.4 0.0 5.1 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR23514.1 - 1.3e-06 28.5 2.5 0.0043 17.3 0.3 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR23514.1 - 0.00024 21.5 0.2 26 5.7 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAR23514.1 - 0.0012 18.7 3.3 2 8.4 0.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CAR23514.1 - 0.0048 16.1 0.1 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat CCP_MauG PF03150.14 CAR23514.1 - 0.0095 16.6 4.0 0.046 14.4 3.2 2.4 2 1 0 2 2 1 1 Di-haem cytochrome c peroxidase BTAD PF03704.17 CAR23514.1 - 0.035 14.5 1.4 0.077 13.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 CAR23514.1 - 0.25 11.6 1.3 0.55 10.5 0.4 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 CAR23514.1 - 0.38 10.4 2.5 2.6 7.7 0.0 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Glyco_transf_34 PF05637.12 CAR23515.1 - 8.5e-74 248.3 0.0 1.1e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family P-mevalo_kinase PF04275.14 CAR23515.1 - 0.058 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphomevalonate kinase ARID PF01388.21 CAR23516.1 - 8.8e-18 64.8 0.2 3.3e-17 62.9 0.2 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain ERCC4 PF02732.15 CAR23517.1 - 1.6e-22 80.4 0.0 5.5e-22 78.7 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain KAP PF05804.12 CAR23517.1 - 0.0019 16.4 1.0 0.0033 15.7 1.0 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) MTHFR PF02219.17 CAR23518.1 - 2.2e-108 361.9 0.0 3e-108 361.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase RMI1_N PF08585.12 CAR23519.1 - 7.5e-20 71.6 0.0 9.6e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Fib_alpha PF08702.10 CAR23519.1 - 0.058 13.6 0.1 0.097 12.9 0.1 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sybindin PF04099.12 CAR23520.1 - 1.9e-35 121.9 0.2 1.5e-33 115.8 0.2 2.0 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CAR23520.1 - 9.5e-07 29.0 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region NUP PF06516.11 CAR23521.1 - 1.3e-120 402.4 1.1 1.8e-120 401.9 1.1 1.2 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Pkinase PF00069.25 CAR23522.1 - 2.2e-42 145.3 0.0 5.4e-36 124.3 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23522.1 - 5e-19 68.6 0.0 2.2e-15 56.6 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR23522.1 - 2.8e-06 26.8 0.0 1.1e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CAR23522.1 - 0.0027 17.3 0.1 2.6 7.6 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAR23522.1 - 0.0031 17.5 0.1 0.0064 16.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR23522.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CAR23522.1 - 0.014 14.4 0.0 0.035 13.1 0.0 1.6 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APS_kinase PF01583.20 CAR23523.1 - 2.8e-09 37.0 0.0 3.3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase SKI PF01202.22 CAR23523.1 - 2.8e-05 24.3 0.0 3.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.12 CAR23523.1 - 0.00011 21.6 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 CAR23523.1 - 0.00011 22.0 0.1 0.00017 21.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CAR23523.1 - 0.00014 21.5 0.1 0.00031 20.4 0.0 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 CAR23523.1 - 0.0012 19.3 0.2 0.0022 18.5 0.2 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAR23523.1 - 0.0019 18.7 0.0 0.0023 18.4 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CAR23523.1 - 0.0034 17.8 0.1 0.0047 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR23523.1 - 0.004 17.4 0.0 0.0073 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CAR23523.1 - 0.0058 16.6 0.0 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 CAR23523.1 - 0.0095 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PRK PF00485.18 CAR23523.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CAR23523.1 - 0.015 15.4 0.0 0.02 15.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CAR23523.1 - 0.017 15.5 0.1 0.033 14.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 CAR23523.1 - 0.019 14.7 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase NB-ARC PF00931.22 CAR23523.1 - 0.022 13.9 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 CAR23523.1 - 0.024 14.7 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 CAR23523.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Ploopntkinase3 PF18751.1 CAR23523.1 - 0.031 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 DUF2075 PF09848.9 CAR23523.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 CAR23523.1 - 0.033 13.9 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase AAA_24 PF13479.6 CAR23523.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CAR23523.1 - 0.047 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ploopntkinase2 PF18747.1 CAR23523.1 - 0.053 12.8 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 AAA_25 PF13481.6 CAR23523.1 - 0.054 13.1 0.1 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAR23523.1 - 0.057 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CAR23523.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 CAR23523.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAR23523.1 - 0.1 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 CAR23523.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 CAR23523.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 CAR23523.1 - 0.17 12.0 0.0 0.44 10.6 0.0 1.7 2 0 0 2 2 2 0 Torsin Sigma54_activat PF00158.26 CAR23523.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 CAR23523.1 - 0.21 10.6 0.1 0.36 9.8 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Thiolase_N PF00108.23 CAR23524.1 - 7e-96 320.6 1.3 1e-95 320.0 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CAR23524.1 - 8.7e-45 151.3 2.9 1.5e-44 150.6 0.1 2.5 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CAR23524.1 - 1.3e-05 24.9 2.0 2.7e-05 23.9 2.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SUV3_C PF12513.8 CAR23525.1 - 1.1e-19 70.1 1.3 2.5e-19 68.9 1.3 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CAR23525.1 - 2e-13 50.7 0.0 8.4e-13 48.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4771 PF15995.5 CAR23525.1 - 0.08 13.2 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4771) AdoMet_MTase PF07757.13 CAR23526.1 - 5.7e-42 142.6 0.2 1e-41 141.8 0.2 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 CAR23526.1 - 0.004 16.9 0.2 0.0086 15.9 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CAR23526.1 - 0.095 12.3 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 CAR23526.1 - 0.17 11.8 0.2 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 CAR23527.1 - 2.3e-75 253.4 0.0 2.6e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23527.1 - 1.5e-36 126.0 0.0 2.1e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR23527.1 - 0.004 17.1 0.0 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CAR23527.1 - 0.009 15.4 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAR23527.1 - 0.014 14.3 0.0 0.071 12.0 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CAR23527.1 - 0.083 12.2 0.2 16 4.8 0.0 2.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family ApbA PF02558.16 CAR23529.1 - 3.2e-06 26.9 0.0 8.2e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CAR23529.1 - 6.8e-06 26.3 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Fez1 PF06818.15 CAR23529.1 - 0.029 14.8 9.0 0.025 15.0 4.1 2.2 2 0 0 2 2 2 0 Fez1 OmpH PF03938.14 CAR23529.1 - 0.89 9.9 11.7 1.4 9.3 4.5 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 CAR23529.1 - 1.3 8.2 3.3 2.5 7.3 3.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein Uso1_p115_C PF04871.13 CAR23529.1 - 8.4 6.8 16.2 0.21 12.0 8.6 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region NAC PF01849.18 CAR23530.1 - 1.7e-17 63.1 0.2 3e-17 62.3 0.2 1.4 1 0 0 1 1 1 1 NAC domain TT_ORF2 PF02957.15 CAR23530.1 - 5.9 7.8 7.4 8.5 7.3 0.4 2.1 2 0 0 2 2 2 0 TT viral ORF2 zf-C2H2 PF00096.26 CAR23531.1 - 6e-11 42.2 3.5 1.4e-05 25.3 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR23531.1 - 2.5e-09 37.2 2.2 0.0027 18.4 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR23531.1 - 0.00064 19.9 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CAR23531.1 - 0.0011 18.9 0.4 1.4 9.0 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CAR23531.1 - 0.0021 18.7 0.4 0.02 15.6 0.0 2.1 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CAR23531.1 - 0.0063 16.9 0.1 0.5 10.8 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CAR23531.1 - 0.065 13.0 2.0 0.77 9.6 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 CAR23531.1 - 0.72 10.4 6.3 2.7 8.6 0.6 3.3 3 1 0 3 3 3 0 Zinc-finger double domain tRNA-synt_1 PF00133.22 CAR23532.1 - 2.9e-155 517.9 0.0 3.8e-155 517.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CAR23532.1 - 1.8e-18 67.0 0.6 4.2e-18 65.8 0.6 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CAR23532.1 - 7.5e-18 64.4 0.0 5.9e-11 41.8 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) DUF4080 PF13311.6 CAR23532.1 - 0.064 13.5 3.9 0.047 13.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4080) PI_PP_I PF18363.1 CAR23532.1 - 0.17 12.0 7.5 26 5.1 0.0 3.8 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain FLILHELTA PF10306.9 CAR23533.1 - 1.1e-22 80.3 0.0 1.7e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Pkinase PF00069.25 CAR23534.1 - 6.2e-57 193.0 0.0 1.5e-55 188.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23534.1 - 4.8e-26 91.6 0.0 7.8e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR23534.1 - 0.012 14.5 0.2 0.022 13.7 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Imm7 PF15585.6 CAR23534.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 RRM_1 PF00076.22 CAR23535.1 - 3.5e-56 186.9 1.8 3.1e-17 62.2 0.2 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR23535.1 - 1.9e-08 34.3 0.4 0.00013 22.0 0.0 4.1 4 1 0 4 4 4 1 RNA recognition motif BSP_II PF05432.11 CAR23535.1 - 0.0031 17.3 16.9 0.0031 17.3 16.9 2.8 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) RRM_Rrp7 PF17799.1 CAR23535.1 - 0.0064 16.3 0.0 4.8 7.0 0.0 3.2 2 1 0 2 2 2 2 Rrp7 RRM-like N-terminal domain CENP-N PF05238.13 CAR23536.1 - 8.3e-70 236.2 0.0 9.8e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF4170 PF13773.6 CAR23536.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) PXA PF02194.15 CAR23536.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 PXA domain Vps16_C PF04840.12 CAR23537.1 - 1.6e-74 250.8 6.8 1.6e-74 250.8 6.8 1.8 2 0 0 2 2 2 1 Vps16, C-terminal region Vps16_N PF04841.13 CAR23537.1 - 1.2e-62 212.1 0.0 1.8e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Sterile PF03015.19 CAR23537.1 - 0.028 14.6 2.5 0.4 10.9 0.3 3.3 3 0 0 3 3 3 0 Male sterility protein Skp1_POZ PF03931.15 CAR23538.1 - 5.9e-11 42.4 0.2 1.7e-10 40.9 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 CAR23538.1 - 2.3e-05 24.6 0.1 3.2e-05 24.1 0.1 1.3 1 1 0 1 1 1 1 BTB/POZ domain ANTH PF07651.16 CAR23538.1 - 0.056 12.4 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 ANTH domain CLTH PF10607.9 CAR23539.1 - 4e-11 43.0 2.0 4.8e-11 42.8 0.1 2.0 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Acyltransf_C PF16076.5 CAR23539.1 - 0.0012 18.9 0.0 0.0037 17.3 0.0 1.9 1 0 0 1 1 1 1 Acyltransferase C-terminus zf-RING_UBOX PF13445.6 CAR23539.1 - 0.0031 17.5 3.1 0.0086 16.1 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger RNase_E_G PF10150.9 CAR23539.1 - 0.17 11.2 0.2 0.32 10.4 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease E/G family Sgf11_N PF18519.1 CAR23540.1 - 1.5e-21 75.7 0.5 2.1e-21 75.2 0.5 1.2 1 0 0 1 1 1 1 SAGA-associated factor 11 N-terminal domain Sgf11 PF08209.11 CAR23540.1 - 1.6e-16 59.5 2.2 2.2e-16 59.1 2.2 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 CAR23540.1 - 0.027 14.3 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Catalase PF00199.19 CAR23541.1 - 5.7e-185 614.9 1.4 7e-185 614.6 1.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CAR23541.1 - 1.4e-12 47.6 0.1 6.1e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive HU-CCDC81_bac_2 PF18175.1 CAR23541.1 - 0.084 12.8 0.0 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 EF1G PF00647.19 CAR23542.1 - 1.9e-42 143.6 0.0 3.4e-42 142.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CAR23542.1 - 1.9e-11 44.1 0.0 6.5e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CAR23542.1 - 6e-09 36.0 0.0 6e-09 36.0 0.0 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR23542.1 - 2.6e-06 27.4 0.4 5.6e-06 26.3 0.4 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CAR23542.1 - 0.0029 17.8 0.1 0.0029 17.8 0.1 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAR23542.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Anp1 PF03452.14 CAR23544.1 - 3.8e-107 357.6 0.1 4.6e-107 357.3 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CAR23544.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Alk_phosphatase PF00245.20 CAR23545.1 - 1.1e-122 410.1 0.2 1.3e-122 409.8 0.2 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CAR23545.1 - 1.5e-05 24.5 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CAR23545.1 - 0.044 13.2 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Sulfatase Arf PF00025.21 CAR23546.1 - 3e-48 163.5 0.0 3.7e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CAR23546.1 - 1.8e-15 56.9 0.0 2.2e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR23546.1 - 1.1e-14 54.6 0.0 1.8e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CAR23546.1 - 1.5e-11 44.1 0.1 2.9e-06 26.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CAR23546.1 - 1.8e-11 43.8 0.0 2.8e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CAR23546.1 - 1.3e-07 31.3 0.0 3.5e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAR23546.1 - 1.7e-07 30.9 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR23546.1 - 6.8e-07 29.4 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CAR23546.1 - 0.00048 20.4 0.0 0.007 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.18 CAR23546.1 - 0.025 14.1 0.4 0.11 12.0 0.4 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Thymidylate_kin PF02223.17 CAR23546.1 - 0.027 14.2 0.4 0.068 12.8 0.1 1.8 2 0 0 2 2 2 0 Thymidylate kinase RsgA_GTPase PF03193.16 CAR23546.1 - 0.032 14.1 0.1 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 CAR23546.1 - 0.046 13.1 0.1 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 CAR23546.1 - 0.095 13.2 0.2 0.44 11.1 0.2 2.1 1 1 0 1 1 1 0 AAA domain cwf21 PF08312.12 CAR23547.1 - 4.8e-13 49.0 1.1 4.8e-13 49.0 1.1 1.7 2 0 0 2 2 2 1 cwf21 domain ECH_2 PF16113.5 CAR23547.1 - 0.29 10.6 2.8 0.34 10.4 2.8 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ODC_AZ PF02100.17 CAR23548.1 - 6.7e-08 32.5 0.1 9.6e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Glyco_transf_15 PF01793.16 CAR23549.1 - 2e-130 434.8 8.2 2.5e-130 434.5 8.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase L_lactis_ph-MCP PF06673.11 CAR23549.1 - 0.053 12.5 0.2 0.084 11.9 0.2 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein TPR_1 PF00515.28 CAR23550.1 - 6.4e-10 38.4 14.9 0.00068 19.3 1.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR23550.1 - 1.2e-07 31.3 14.2 0.021 14.9 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAR23550.1 - 3.6e-05 24.0 3.4 0.014 15.7 0.1 3.1 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR23550.1 - 0.0044 17.2 8.2 0.028 14.6 7.2 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CAR23550.1 - 0.0056 17.4 0.8 2.1 9.4 0.2 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat DUF3808 PF10300.9 CAR23550.1 - 0.0073 15.1 3.0 0.01 14.6 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.6 CAR23550.1 - 0.017 15.6 3.5 0.4 11.2 2.2 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR23550.1 - 0.025 14.6 1.3 0.025 14.6 1.3 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 CAR23550.1 - 0.034 14.3 9.4 0.064 13.5 0.6 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR23550.1 - 0.063 13.9 2.0 2.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR23550.1 - 0.22 12.0 1.4 2.3 8.8 0.9 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAR23550.1 - 1 9.1 8.9 8 6.2 0.2 3.5 3 1 0 3 3 3 0 TPR repeat INCENP_ARK-bind PF03941.15 CAR23551.1 - 6.2e-15 54.9 3.0 1.5e-14 53.6 3.0 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region AA_permease PF00324.21 CAR23552.1 - 4.2e-80 269.7 42.6 6.7e-79 265.7 42.6 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23552.1 - 5.2e-26 91.5 38.8 4.9e-25 88.2 38.8 2.0 1 1 0 1 1 1 1 Amino acid permease Prp19 PF08606.11 CAR23552.1 - 0.05 13.6 1.8 0.49 10.4 1.8 2.2 1 1 0 1 1 1 0 Prp19/Pso4-like DUF4181 PF13789.6 CAR23552.1 - 1.1 9.6 8.5 0.35 11.2 1.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) UPF0560 PF10577.9 CAR23553.1 - 0.0044 15.6 0.5 0.0047 15.5 0.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 zf-CCCH PF00642.24 CAR23554.1 - 5.2e-12 45.4 13.6 7e-07 29.0 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAR23554.1 - 4.3e-11 42.5 20.0 3.9e-06 26.7 3.2 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CAR23554.1 - 7.2e-11 41.6 12.4 3.4e-05 23.5 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CAR23554.1 - 5e-08 33.6 8.3 0.0012 19.5 1.0 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 CAR23554.1 - 6.3e-07 29.6 1.4 1.1e-06 28.8 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CAR23554.1 - 0.00015 22.1 16.2 0.0099 16.3 2.8 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger LRR_4 PF12799.7 CAR23555.1 - 0.019 15.4 2.6 3 8.4 0.9 2.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAR23555.1 - 3.4 8.6 5.0 81 4.4 0.5 3.6 3 1 0 3 3 3 0 Leucine Rich Repeat Lge1 PF11488.8 CAR23556.1 - 2.2e-21 75.8 6.1 2.8e-21 75.4 6.1 1.1 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.25 CAR23557.1 - 6.4e-35 120.4 0.0 8.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR23557.1 - 5.5e-20 71.9 0.0 7.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR23557.1 - 3.6e-07 30.3 0.0 9.1e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CAR23557.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DUF3395 PF11875.8 CAR23557.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Polysacc_synt_2 PF02719.15 CAR23557.1 - 0.12 11.5 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 CAR23558.1 - 1.1e-73 247.8 0.0 1.3e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23558.1 - 4.7e-33 114.6 0.0 5.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR23558.1 - 0.00014 21.3 0.0 0.00024 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR23558.1 - 0.0006 19.8 0.2 0.015 15.2 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAR23558.1 - 0.00069 18.7 0.0 0.0053 15.8 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR23558.1 - 0.01 15.2 0.2 0.032 13.6 0.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gly_transf_sug PF04488.15 CAR23559.1 - 1.2e-19 70.7 0.0 2.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 CAR23559.1 - 0.18 11.1 1.3 3.4 6.9 0.2 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.9 CAR23560.1 - 7.5e-93 310.3 3.4 7.5e-93 310.3 3.4 2.0 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CAR23560.1 - 1.3e-28 99.2 0.1 4.2e-28 97.6 0.1 2.0 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SPX PF03105.19 CAR23560.1 - 0.12 12.2 11.9 0.16 11.9 11.9 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CAR23560.1 - 0.19 10.5 12.0 0.24 10.2 12.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CAR23560.1 - 0.26 9.8 16.3 0.33 9.5 16.3 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CAR23560.1 - 3.3 4.7 9.0 3.7 4.6 9.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RAMP4 PF06624.12 CAR23561.1 - 7.6e-11 41.9 0.1 8.4e-11 41.8 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Exo5 PF09810.9 CAR23562.1 - 7.2e-64 216.6 0.1 9.5e-64 216.2 0.1 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Cas_Cas4 PF01930.17 CAR23562.1 - 0.004 17.3 3.7 0.42 10.7 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 CAR23562.1 - 0.034 14.1 7.2 0.15 11.9 4.6 2.7 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Glutaredoxin PF00462.24 CAR23563.1 - 8.5e-18 64.3 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Amidase PF01425.21 CAR23564.1 - 5.3e-94 315.7 0.0 7.5e-94 315.2 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 CAR23564.1 - 1e-88 297.4 0.0 1.8e-88 296.6 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 CAR23564.1 - 7.2e-64 215.2 0.0 1.4e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 CAR23564.1 - 9.7e-44 149.5 0.0 1.9e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 CAR23564.1 - 5.9e-41 139.5 0.0 1.3e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAR23564.1 - 8.9e-34 115.8 0.0 2.7e-33 114.3 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CAR23564.1 - 2.6e-18 65.6 3.9 5.2e-18 64.7 1.9 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CAR23564.1 - 1.4e-11 44.3 0.0 3.2e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CAR23564.1 - 7.3e-06 26.1 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 CAR23564.1 - 1.2e-05 25.0 0.0 2.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 CAR23564.1 - 0.004 16.6 0.1 0.012 15.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain RnfC_N PF13375.6 CAR23564.1 - 0.13 12.2 0.3 0.58 10.1 0.1 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 CAR23564.1 - 0.66 9.9 7.6 3.7 7.4 0.8 3.0 2 1 1 3 3 3 0 Biotin-lipoyl like FTR1 PF03239.14 CAR23565.1 - 3.4e-95 318.8 9.1 4e-95 318.5 9.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family S_2TMBeta PF18153.1 CAR23565.1 - 0.024 14.4 0.5 0.07 12.9 0.5 1.7 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain Amidase_5 PF05382.13 CAR23565.1 - 0.12 12.2 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase ThrE PF06738.12 CAR23565.1 - 0.25 10.7 5.4 0.18 11.2 0.3 2.3 2 0 0 2 2 2 0 Putative threonine/serine exporter DUF2207 PF09972.9 CAR23565.1 - 0.88 8.3 2.8 0.54 9.0 0.2 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CorA PF01544.18 CAR23566.1 - 0.00019 20.9 4.3 0.00027 20.4 4.2 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF350 PF03994.14 CAR23566.1 - 0.09 12.9 1.3 0.8 9.9 1.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF350) Glyco_transf_15 PF01793.16 CAR23567.1 - 9e-130 432.7 10.2 1.2e-129 432.3 10.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Peptidase_A2E PF12382.8 CAR23567.1 - 0.11 12.5 0.1 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon peptidase Say1_Mug180 PF10340.9 CAR23568.1 - 3.6e-42 144.6 0.0 2.3e-40 138.6 0.0 2.0 1 1 1 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CAR23568.1 - 3.2e-21 76.2 0.0 4.2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR23568.1 - 0.0056 16.0 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DRMBL PF07522.14 CAR23568.1 - 0.095 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase Abhydrolase_6 PF12697.7 CAR23569.1 - 8.3e-22 78.9 0.0 1e-21 78.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAR23569.1 - 2.3e-15 56.9 0.2 3.6e-11 43.2 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR23569.1 - 8.9e-12 44.8 0.2 8.7e-11 41.5 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CAR23569.1 - 6.7e-06 26.1 0.0 7e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CAR23569.1 - 9.1e-06 25.9 0.2 3.2e-05 24.1 0.1 1.8 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 CAR23569.1 - 2e-05 24.5 0.0 0.00019 21.3 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_2 PF02230.16 CAR23569.1 - 4.8e-05 23.3 1.3 0.22 11.3 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 CAR23569.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase LCAT PF02450.15 CAR23569.1 - 0.00014 21.1 0.1 0.0027 16.9 0.1 2.1 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.21 CAR23569.1 - 0.0027 17.2 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1057 PF06342.12 CAR23569.1 - 0.0055 15.8 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Say1_Mug180 PF10340.9 CAR23569.1 - 0.026 13.4 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF1749 PF08538.10 CAR23569.1 - 0.049 12.7 0.1 0.1 11.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Ndr PF03096.14 CAR23569.1 - 0.071 11.8 0.0 2.5 6.7 0.0 2.1 2 0 0 2 2 2 0 Ndr family PGAP1 PF07819.13 CAR23569.1 - 0.081 12.6 1.3 0.51 10.0 1.3 2.2 1 1 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.7 CAR23569.1 - 0.1 11.5 0.1 0.25 10.2 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_4 PF08386.10 CAR23569.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Aldedh PF00171.22 CAR23570.1 - 6.7e-177 588.6 0.1 7.7e-177 588.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box-like PF12937.7 CAR23571.1 - 0.0034 17.3 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like NIF PF03031.18 CAR23572.1 - 3.4e-43 147.1 0.0 5.5e-43 146.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pro_isomerase PF00160.21 CAR23573.1 - 1.3e-10 41.8 0.0 6.3e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VPS28 PF03997.12 CAR23574.1 - 6.8e-73 244.4 4.5 8e-73 244.2 4.5 1.0 1 0 0 1 1 1 1 VPS28 protein Arrestin_C PF02752.22 CAR23575.1 - 0.0087 16.5 0.0 0.19 12.2 0.0 2.5 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MCM PF00493.23 CAR23576.1 - 3.8e-103 343.4 0.0 6.8e-103 342.6 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR23576.1 - 1e-32 112.6 1.2 1.7e-32 111.9 1.2 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAR23576.1 - 8.9e-22 77.3 2.3 9.9e-22 77.2 0.6 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CAR23576.1 - 9.8e-17 61.5 0.1 4.3e-16 59.4 0.1 2.2 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR23576.1 - 8.6e-07 28.5 0.1 0.00014 21.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAR23576.1 - 1.4e-05 25.1 0.0 4.7e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 CAR23576.1 - 0.0012 19.4 0.1 0.0043 17.6 0.1 1.9 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI C-terminal AAA_16 PF13191.6 CAR23576.1 - 0.0089 16.4 0.5 4.8 7.5 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain MCM_bind PF09739.9 CAR23576.1 - 0.023 13.2 0.1 0.037 12.5 0.1 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor AAA_3 PF07726.11 CAR23576.1 - 0.074 12.9 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CAR23576.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain DUF3605 PF12239.8 CAR23577.1 - 3.4e-40 137.9 0.0 3.9e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DER1 PF04511.15 CAR23579.1 - 1.5e-28 100.0 7.4 2.5e-28 99.3 7.4 1.3 1 1 0 1 1 1 1 Der1-like family Mg296 PF09644.10 CAR23579.1 - 0.011 15.9 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Mg296 protein DUF4149 PF13664.6 CAR23579.1 - 0.044 14.1 3.4 0.076 13.3 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) polyprenyl_synt PF00348.17 CAR23580.1 - 1.1e-55 188.5 0.0 1.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase VPS9 PF02204.18 CAR23581.1 - 1.2e-19 70.4 0.7 2.5e-19 69.4 0.7 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ipi1_N PF12333.8 CAR23583.1 - 0.1 13.2 1.9 1.5 9.5 0.2 3.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation SH3_1 PF00018.28 CAR23584.1 - 6.7e-23 80.1 0.0 2.7e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.24 CAR23584.1 - 2e-14 53.6 0.0 4.1e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 CAR23584.1 - 1.2e-11 44.3 0.2 2.5e-08 33.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CAR23584.1 - 2.7e-06 26.9 0.0 1.8e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 Variant SH3 domain PB1 PF00564.24 CAR23584.1 - 0.0017 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 PB1 domain UCH PF00443.29 CAR23585.1 - 3e-29 102.3 4.0 3.4e-27 95.6 1.3 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 CAR23586.1 - 2.4e-37 128.3 0.0 8.1e-37 126.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR23586.1 - 3.9e-09 36.2 0.0 1e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CAR23586.1 - 2.2e-06 27.6 0.3 8e-06 25.8 0.1 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CAR23586.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAR23586.1 - 0.0017 18.3 0.2 0.1 12.6 0.0 3.7 3 2 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR23586.1 - 0.0021 18.2 0.8 0.0063 16.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CAR23586.1 - 0.0025 18.3 2.8 0.024 15.2 0.0 3.4 3 2 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CAR23586.1 - 0.0079 16.5 3.7 0.11 12.8 0.4 3.0 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 CAR23586.1 - 0.01 15.2 0.0 2.3 7.6 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein TIP49 PF06068.13 CAR23586.1 - 0.031 13.5 0.0 0.078 12.2 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR23586.1 - 0.054 12.9 0.3 0.14 11.5 0.3 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAR23586.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 CAR23586.1 - 0.36 11.2 6.0 0.83 10.0 0.1 3.4 3 1 0 4 4 4 0 AAA ATPase domain GCR1_C PF12550.8 CAR23587.1 - 5.4e-25 87.5 2.5 1.1e-24 86.5 1.6 2.1 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 CAR23587.1 - 2.1e-08 33.6 0.3 3.7e-06 26.2 0.1 2.3 2 0 0 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Occludin_ELL PF07303.13 CAR23587.1 - 0.078 13.7 1.8 0.23 12.2 1.8 1.8 1 0 0 1 1 1 0 Occludin homology domain UPF0449 PF15136.6 CAR23587.1 - 0.12 12.9 0.6 0.32 11.5 0.6 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Syntaxin-6_N PF09177.11 CAR23587.1 - 0.16 12.6 1.4 0.55 10.8 1.4 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal WD40 PF00400.32 CAR23588.1 - 6.1e-50 166.1 17.3 7.5e-09 36.1 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CAR23588.1 - 9.3e-42 142.3 1.9 1.7e-41 141.5 1.9 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CAR23588.1 - 2.1e-13 50.4 0.0 0.58 10.5 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR23588.1 - 2.4e-06 26.7 0.0 0.15 11.0 0.0 3.8 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 CAR23588.1 - 8.3e-06 25.6 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 CAR23588.1 - 7e-05 22.3 0.0 0.82 8.9 0.0 3.5 3 1 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CAR23588.1 - 0.00023 20.0 3.6 0.11 11.1 0.0 3.5 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CAR23588.1 - 0.01 14.4 0.1 0.43 9.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain nos_propeller PF18764.1 CAR23588.1 - 0.019 14.9 0.1 29 4.7 0.0 3.6 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat PD40 PF07676.12 CAR23588.1 - 0.1 12.6 0.0 6.8 6.8 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat GPI2 PF06432.11 CAR23589.1 - 1e-54 185.9 24.7 1.2e-54 185.6 24.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF5315 PF17242.2 CAR23590.1 - 1.3e-27 95.4 2.0 2.6e-27 94.5 2.0 1.5 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) PGI PF00342.19 CAR23591.1 - 3.6e-248 824.0 2.4 4.2e-248 823.8 2.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase CAF1C_H4-bd PF12265.8 CAR23592.1 - 5.3e-17 61.8 1.5 2e-16 60.0 0.5 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CAR23592.1 - 8.5e-10 39.1 15.2 0.00093 20.0 0.7 5.8 5 1 1 6 6 6 4 WD domain, G-beta repeat Lactonase PF10282.9 CAR23592.1 - 0.007 15.7 0.0 0.17 11.1 0.0 2.5 2 1 1 3 3 3 1 Lactonase, 7-bladed beta-propeller Mt_ATP-synt_B PF05405.14 CAR23593.1 - 3.3e-55 186.1 10.3 4e-55 185.9 10.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NpwBP PF12622.7 CAR23594.1 - 1.2e-12 48.4 1.3 2.2e-12 47.5 1.3 1.5 1 0 0 1 1 1 1 mRNA biogenesis factor Med8 PF10232.9 CAR23595.1 - 1.2e-16 61.1 0.5 1.4e-16 60.8 0.5 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Thi4 PF01946.17 CAR23595.1 - 0.072 12.3 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Mito_carr PF00153.27 CAR23596.1 - 5.4e-76 250.6 1.2 2.4e-28 97.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.18 CAR23597.1 - 1.2e-41 140.6 4.9 2.1e-41 139.9 3.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e Surface_Ag_2 PF01617.17 CAR23597.1 - 0.055 12.9 0.3 0.066 12.6 0.3 1.1 1 0 0 1 1 1 0 Surface antigen S4 PF01479.25 CAR23598.1 - 8.5e-11 41.4 0.3 2.8e-10 39.7 0.3 1.9 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CAR23598.1 - 5.4e-05 24.0 0.2 9.8e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain HMGL-like PF00682.19 CAR23599.1 - 6.8e-84 281.5 0.2 1.2e-83 280.7 0.2 1.4 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 CAR23599.1 - 0.0089 16.6 0.2 0.017 15.7 0.2 1.5 1 0 0 1 1 1 1 FliG N-terminal domain FtsX_ECD PF18075.1 CAR23599.1 - 0.1 13.3 0.2 0.3 11.7 0.2 1.8 1 0 0 1 1 1 0 FtsX extracellular domain Oxidored_FMN PF00724.20 CAR23599.1 - 0.11 11.8 0.4 0.32 10.2 0.1 2.0 2 1 0 2 2 2 0 NADH:flavin oxidoreductase / NADH oxidase family DUF3535 PF12054.8 CAR23600.1 - 2.3e-115 386.3 0.2 7.8e-114 381.3 0.0 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CAR23600.1 - 1.1e-65 221.7 0.0 2.2e-65 220.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR23600.1 - 1.6e-18 67.1 0.0 4.6e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CAR23600.1 - 2.4e-16 58.4 2.5 0.0021 18.2 0.0 8.4 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 CAR23600.1 - 1.3e-05 25.5 6.8 6 7.3 0.1 6.3 6 1 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.6 CAR23600.1 - 1.3e-05 25.6 7.9 19 5.9 0.0 8.1 9 0 0 9 9 9 0 HEAT-like repeat TAF6_C PF07571.13 CAR23600.1 - 0.00021 21.6 3.4 2.2 8.7 0.0 5.0 6 1 0 6 6 5 2 TAF6 C-terminal HEAT repeat domain ResIII PF04851.15 CAR23600.1 - 0.0003 20.8 0.0 0.0026 17.8 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Vac14_Fab1_bd PF12755.7 CAR23600.1 - 0.00056 20.5 0.1 5.8 7.6 0.0 4.6 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region ERCC3_RAD25_C PF16203.5 CAR23600.1 - 0.011 14.9 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GUN4_N PF16416.5 CAR23600.1 - 0.13 12.3 0.6 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal U3snoRNP10 PF12397.8 CAR23600.1 - 0.42 11.0 4.0 0.37 11.2 1.0 2.7 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 cwf18 PF08315.12 CAR23601.1 - 1.6e-12 48.3 7.5 2.4e-12 47.7 7.5 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor Yos9_DD PF17880.1 CAR23601.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Yos9 dimerzation domain DASH_Spc19 PF08287.11 CAR23601.1 - 0.52 10.2 9.8 0.96 9.3 1.1 2.4 1 1 1 2 2 2 0 Spc19 UPF0016 PF01169.19 CAR23602.1 - 6.4e-40 135.3 27.6 2.2e-21 75.9 6.4 2.4 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 AAA PF00004.29 CAR23603.1 - 1.2e-31 109.8 0.0 2.6e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR23603.1 - 7.1e-09 36.1 0.7 3.5e-08 33.8 0.0 2.4 3 1 1 4 4 2 1 AAA domain AAA_16 PF13191.6 CAR23603.1 - 2.5e-07 31.2 0.1 1.8e-06 28.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 CAR23603.1 - 1.1e-06 28.9 0.0 0.00089 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CAR23603.1 - 5.7e-06 26.4 0.2 2.2e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_11 PF13086.6 CAR23603.1 - 6.8e-06 26.0 0.7 1.3e-05 25.1 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR23603.1 - 1.5e-05 25.6 0.2 0.0004 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CAR23603.1 - 9e-05 22.5 0.1 0.00041 20.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain Cytidylate_kin PF02224.18 CAR23603.1 - 0.00012 21.8 0.0 0.0028 17.4 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase AAA_19 PF13245.6 CAR23603.1 - 0.00021 21.6 0.1 0.0009 19.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CAR23603.1 - 0.00033 20.2 0.0 0.00085 18.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 CAR23603.1 - 0.00034 20.0 0.0 0.00053 19.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CAR23603.1 - 0.00039 20.2 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR23603.1 - 0.0011 19.4 0.0 0.0049 17.2 0.0 2.2 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.12 CAR23603.1 - 0.0013 18.7 0.6 0.0048 16.8 0.3 2.2 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 CAR23603.1 - 0.0016 19.0 0.1 0.023 15.2 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_5 PF07728.14 CAR23603.1 - 0.0018 18.3 0.3 0.02 14.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CAR23603.1 - 0.0022 18.6 1.4 0.0043 17.6 0.2 2.1 2 1 0 2 2 1 1 AAA domain TniB PF05621.11 CAR23603.1 - 0.0037 16.7 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein TsaE PF02367.17 CAR23603.1 - 0.0042 17.1 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CAR23603.1 - 0.005 16.9 0.7 0.13 12.4 0.7 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.26 CAR23603.1 - 0.0056 16.4 0.1 0.072 12.8 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.22 CAR23603.1 - 0.0057 15.9 0.0 0.012 14.8 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain RuvB_N PF05496.12 CAR23603.1 - 0.0062 16.3 0.0 0.021 14.6 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 CAR23603.1 - 0.0067 16.4 0.3 0.074 13.0 0.3 2.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 CAR23603.1 - 0.0074 15.4 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 CAR23603.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CAR23603.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.6 CAR23603.1 - 0.011 16.1 0.9 0.058 13.8 0.0 2.7 4 0 0 4 4 1 0 AAA domain IstB_IS21 PF01695.17 CAR23603.1 - 0.018 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CAR23603.1 - 0.025 14.8 0.0 0.092 13.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CAR23603.1 - 0.027 14.2 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 CAR23603.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase ResIII PF04851.15 CAR23603.1 - 0.031 14.3 0.2 0.2 11.6 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CAR23603.1 - 0.042 13.6 0.1 0.11 12.2 0.1 1.8 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 CAR23603.1 - 0.052 13.5 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 NTPase PhoH PF02562.16 CAR23603.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein cobW PF02492.19 CAR23603.1 - 0.072 12.7 0.0 0.68 9.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 CAR23603.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI tRNA_int_end_N2 PF12928.7 CAR23604.1 - 5.5e-17 61.7 0.0 1.3e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term SH3BGR PF04908.15 CAR23604.1 - 0.051 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein tRNA_int_endo_N PF02778.14 CAR23604.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain BRO1 PF03097.18 CAR23605.1 - 4.2e-94 315.5 9.9 7.5e-94 314.7 9.9 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CAR23605.1 - 2.8e-26 92.5 8.8 6.8e-26 91.2 8.8 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Piwi PF02171.17 CAR23605.1 - 0.00065 19.0 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Piwi domain MBA1 PF07961.11 CAR23606.1 - 1.7e-100 334.9 1.5 1.9e-100 334.7 1.5 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.21 CAR23606.1 - 0.0093 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 LON_substr_bdg PF02190.16 CAR23606.1 - 0.08 12.8 0.3 0.67 9.8 0.1 2.1 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain Sec16_C PF12931.7 CAR23607.1 - 8.5e-71 239.1 0.3 1.3e-70 238.5 0.3 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CAR23607.1 - 2.7e-08 34.4 0.0 1.9e-07 31.7 0.0 2.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Radical_SAM_C PF16199.5 CAR23608.1 - 3.4e-32 110.3 0.0 6.9e-32 109.3 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CAR23608.1 - 7.8e-18 65.4 0.5 2.7e-17 63.7 0.1 2.0 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CAR23608.1 - 3.5e-10 40.1 0.1 6.7e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR23608.1 - 4.8e-06 26.5 0.1 1.1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR23608.1 - 0.011 16.2 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Beta_elim_lyase PF01212.21 CAR23609.1 - 2.8e-56 191.0 0.0 3.3e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 CAR23609.1 - 0.093 11.4 0.0 0.4 9.4 0.0 1.8 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain Ceramidase PF05875.12 CAR23610.1 - 3.6e-95 318.4 10.0 4.2e-95 318.1 10.0 1.0 1 0 0 1 1 1 1 Ceramidase adh_short_C2 PF13561.6 CAR23611.1 - 2.5e-58 197.4 1.5 2.9e-58 197.2 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR23611.1 - 2e-38 131.8 2.2 2.3e-38 131.6 2.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR23611.1 - 5e-06 26.6 1.9 8e-06 25.9 1.9 1.3 1 0 0 1 1 1 1 KR domain Mrr_cat PF04471.12 CAR23611.1 - 0.039 14.0 0.7 0.18 11.9 0.4 2.0 2 0 0 2 2 2 0 Restriction endonuclease GPW_gp25 PF04965.14 CAR23611.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Gene 25-like lysozyme SRF-TF PF00319.18 CAR23612.1 - 8e-21 73.3 0.0 1.3e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) YL1 PF05764.13 CAR23612.1 - 0.00064 19.9 7.7 0.023 14.8 0.4 2.3 2 0 0 2 2 2 2 YL1 nuclear protein Spt20 PF12090.8 CAR23612.1 - 0.0037 16.9 24.2 0.0037 16.9 24.2 2.4 2 0 0 2 2 2 1 Spt20 family SDA1 PF05285.12 CAR23612.1 - 0.051 13.0 11.8 0.12 11.8 3.8 2.2 2 0 0 2 2 2 0 SDA1 NOA36 PF06524.12 CAR23612.1 - 0.084 12.2 17.2 0.014 14.7 10.2 2.1 2 0 0 2 2 2 0 NOA36 protein RR_TM4-6 PF06459.12 CAR23612.1 - 0.27 11.0 6.6 0.81 9.5 2.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RXT2_N PF08595.11 CAR23612.1 - 0.32 11.0 11.6 1.3 9.1 3.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal CDC45 PF02724.14 CAR23612.1 - 0.38 9.0 15.8 0.22 9.8 5.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 CAR23612.1 - 0.48 10.1 19.8 0.4 10.4 8.1 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SURF2 PF05477.11 CAR23612.1 - 0.8 9.3 11.8 0.19 11.4 3.4 2.2 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) SAPS PF04499.15 CAR23612.1 - 0.89 8.3 9.2 2.3 6.9 0.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CNDH2_C PF16858.5 CAR23612.1 - 2.2 8.1 16.3 0.97 9.3 4.1 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term EIIBC-GUT_N PF03612.14 CAR23612.1 - 2.3 7.9 7.1 5.1 6.8 7.1 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 CAR23612.1 - 2.5 7.8 14.4 2.9 7.5 1.5 2.3 2 0 0 2 2 2 0 FAM176 family Afi1 PF07792.12 CAR23612.1 - 3.3 8.2 14.5 6 7.4 3.7 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nop14 PF04147.12 CAR23612.1 - 4 5.5 16.3 0.064 11.5 4.0 2.0 2 0 0 2 2 2 0 Nop14-like family CPSF100_C PF13299.6 CAR23612.1 - 4.1 7.6 11.9 0.82 9.8 3.3 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SIN1 PF05422.12 CAR23612.1 - 4.2 7.9 20.9 0.03 14.9 8.9 2.5 2 0 0 2 2 2 0 Stress-activated map kinase interacting protein 1 (SIN1) PTPRCAP PF15713.5 CAR23612.1 - 4.9 7.4 20.7 5.5 7.3 5.2 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Tim54 PF11711.8 CAR23612.1 - 8 5.1 10.9 0.7 8.6 3.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FAM60A PF15396.6 CAR23612.1 - 8.5 6.3 7.3 2.2 8.2 1.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A PBP1_TM PF14812.6 CAR23612.1 - 9.2 6.7 19.5 6.2 7.3 12.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal D123 PF07065.14 CAR23612.1 - 9.7 5.2 12.3 6.3 5.9 3.7 2.4 2 0 0 2 2 2 0 D123 Ribosomal_S6e PF01092.19 CAR23613.1 - 5.4e-57 191.2 0.2 5.4e-57 191.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e Pyr_redox_2 PF07992.14 CAR23614.1 - 4.3e-62 210.0 2.9 6.7e-62 209.4 2.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAR23614.1 - 2.7e-35 120.9 1.4 1.2e-34 118.9 0.3 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAR23614.1 - 2e-18 66.7 6.0 6.8e-18 65.0 0.9 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR23614.1 - 1.1e-11 44.5 7.6 4.7e-11 42.5 0.7 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR23614.1 - 2.6e-06 27.1 0.1 4.4e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CAR23614.1 - 2.4e-05 23.2 3.2 0.25 10.0 0.5 3.5 3 0 0 3 3 3 3 HI0933-like protein K_oxygenase PF13434.6 CAR23614.1 - 3.5e-05 23.1 0.0 6.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 CAR23614.1 - 0.00041 19.6 4.1 0.00083 18.5 0.6 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CAR23614.1 - 0.0006 19.2 1.5 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CAR23614.1 - 0.024 13.7 7.2 0.2 10.7 1.5 2.8 2 1 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.19 CAR23614.1 - 0.031 13.6 0.5 6.6 6.0 0.0 3.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 CAR23614.1 - 0.34 10.4 1.6 5.1 6.6 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase MFS_1 PF07690.16 CAR23615.1 - 3.4e-44 151.2 30.6 3.4e-44 151.2 30.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR23615.1 - 2.5e-19 69.5 18.7 3.6e-18 65.7 0.5 3.2 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_4 PF06779.14 CAR23615.1 - 4.5e-06 26.2 7.5 4.5e-06 26.2 7.5 2.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB NOG1_N PF17835.1 CAR23616.1 - 1.4e-49 168.2 0.1 1.4e-49 168.2 0.1 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CAR23616.1 - 1e-25 89.5 2.0 1e-25 89.5 2.0 2.2 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 CAR23616.1 - 4.4e-25 87.2 0.2 4.4e-25 87.2 0.2 1.9 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CAR23616.1 - 1.4e-16 60.6 0.0 8.5e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR23616.1 - 9.2e-08 31.8 0.0 2.6e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CAR23616.1 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 CAR23616.1 - 0.0065 16.5 0.0 1.8 8.6 0.0 3.1 1 1 1 2 2 2 1 Dynamin family AAA_16 PF13191.6 CAR23616.1 - 0.0069 16.8 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RisS_PPD PF16524.5 CAR23616.1 - 0.033 14.4 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS Roc PF08477.13 CAR23616.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CAR23616.1 - 0.45 11.0 0.0 0.45 11.0 0.0 2.6 2 1 0 2 2 1 0 AAA domain Sec62 PF03839.16 CAR23617.1 - 4.1e-75 252.0 0.0 5e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Translocation protein Sec62 BRI3BP PF14965.6 CAR23617.1 - 0.29 10.6 2.3 0.44 10.0 2.3 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 DUF2070 PF09843.9 CAR23617.1 - 1.8 6.7 3.3 2.4 6.3 3.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Dynamin_N PF00350.23 CAR23618.1 - 8.2e-17 61.8 0.1 2e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CAR23618.1 - 2.3e-10 40.5 0.0 1.5e-09 37.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR23618.1 - 1.4e-08 34.5 0.0 6.4e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.19 CAR23618.1 - 0.0036 16.9 0.4 0.076 12.6 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CAR23618.1 - 0.016 15.8 0.1 0.3 11.6 0.0 3.2 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 CAR23618.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IIGP PF05049.13 CAR23618.1 - 0.042 12.9 1.7 0.14 11.2 0.0 2.4 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) PduV-EutP PF10662.9 CAR23618.1 - 0.066 13.0 0.1 22 4.8 0.1 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CAR23618.1 - 0.21 11.1 0.7 17 4.9 0.2 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR23618.1 - 0.53 10.2 3.3 2.4 8.0 0.0 3.0 3 1 0 4 4 4 0 RsgA GTPase Abhydrolase_1 PF00561.20 CAR23619.1 - 3.7e-23 82.5 0.0 1.2e-22 80.8 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR23619.1 - 1.1e-08 34.6 0.0 7e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR23619.1 - 0.00016 22.4 0.0 0.00035 21.2 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family ORC3_N PF07034.11 CAR23619.1 - 0.0077 15.4 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Palm_thioest PF02089.15 CAR23619.1 - 0.027 14.3 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Transglut_core PF01841.19 CAR23620.1 - 3e-11 43.7 0.2 7.3e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 CAR23620.1 - 3.5e-10 39.7 0.2 1.1e-09 38.2 0.1 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain PAW PF04721.17 CAR23620.1 - 1.5 8.5 5.1 0.79 9.5 3.0 1.6 2 0 0 2 2 2 0 PNGase C-terminal domain, mannose-binding module PAW tRNA-synt_1b PF00579.25 CAR23621.1 - 6.4e-81 271.9 0.0 8.5e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 CAR23621.1 - 0.0002 21.1 0.7 0.0047 16.7 0.7 2.3 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Romo1 PF10247.9 CAR23622.1 - 6.3e-29 100.1 7.8 8.7e-29 99.7 7.8 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 7TM_GPCR_Srab PF10292.9 CAR23623.1 - 0.13 11.1 0.6 0.17 10.7 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor CutA1 PF03091.15 CAR23623.1 - 0.14 12.0 1.6 0.34 10.8 0.2 2.0 1 1 1 2 2 2 0 CutA1 divalent ion tolerance protein LcrG PF07216.12 CAR23623.1 - 0.33 10.9 2.9 0.2 11.6 0.6 1.7 2 0 0 2 2 2 0 LcrG protein MCU PF04678.13 CAR23623.1 - 1.8 8.6 6.2 0.97 9.5 2.4 1.9 1 1 1 2 2 2 0 Mitochondrial calcium uniporter WD40 PF00400.32 CAR23624.1 - 0.00081 20.1 0.6 0.12 13.3 0.0 4.2 5 1 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23624.1 - 0.056 13.7 0.0 12 6.3 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PAXNEB PF05625.11 CAR23625.1 - 1e-90 304.6 0.2 1.3e-90 304.2 0.2 1.0 1 0 0 1 1 1 1 PAXNEB protein Lactamase_B_2 PF12706.7 CAR23626.1 - 4.8e-30 104.6 0.0 6.7e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CAR23626.1 - 2e-09 37.5 0.0 5.3e-09 36.2 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CAR23626.1 - 0.049 13.6 0.4 0.091 12.8 0.4 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Pantoate_transf PF02548.15 CAR23627.1 - 2.6e-94 315.4 0.0 3.1e-94 315.2 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CAR23627.1 - 0.0013 18.2 0.0 0.0029 17.1 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase MFS_1 PF07690.16 CAR23628.1 - 4.5e-33 114.6 41.3 1.2e-26 93.5 20.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_2 PF00152.20 CAR23629.1 - 4e-100 334.9 0.1 5e-100 334.6 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR23629.1 - 1.9e-06 27.7 0.0 4.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 CAR23629.1 - 0.037 14.0 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 CAR23629.1 - 0.084 12.3 0.0 0.86 9.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) WD40 PF00400.32 CAR23630.1 - 1.5e-23 82.6 12.9 3e-06 27.8 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23630.1 - 1.1e-16 60.9 0.1 1.4e-06 28.5 0.0 4.6 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR23630.1 - 2.3e-05 23.3 0.4 0.17 10.5 0.1 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 CAR23630.1 - 2.8e-05 23.4 0.0 0.00015 21.0 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 CAR23630.1 - 7.8e-05 22.6 0.0 0.79 9.6 0.0 3.1 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 CAR23630.1 - 0.011 14.6 0.1 4 6.3 0.0 3.0 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 CAR23630.1 - 0.015 13.8 0.0 0.039 12.5 0.0 1.8 3 0 0 3 3 3 0 Cytochrome D1 heme domain UMP1 PF05348.11 CAR23631.1 - 4.8e-39 133.2 0.0 6e-39 132.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Miga PF10265.9 CAR23631.1 - 0.045 12.7 0.4 0.049 12.6 0.4 1.0 1 0 0 1 1 1 0 Mitoguardin Metal_resist PF13801.6 CAR23631.1 - 0.19 11.9 1.1 0.26 11.5 1.1 1.1 1 0 0 1 1 1 0 Heavy-metal resistance CUTL PF16557.5 CAR23631.1 - 9.1 6.5 7.4 12 6.2 6.1 1.8 1 1 1 2 2 2 0 CUT1-like DNA-binding domain of SATB GYF PF02213.16 CAR23632.1 - 2.9e-14 52.4 0.0 6e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 GYF domain FGAR-AT_N PF18076.1 CAR23632.1 - 2.6 8.1 6.2 19 5.3 1.8 2.6 1 1 1 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase N-terminal Sec66 PF09802.9 CAR23633.1 - 1.4e-69 233.3 0.8 1.5e-69 233.1 0.8 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Tubulin_3 PF14881.6 CAR23633.1 - 0.081 12.6 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Tubulin domain NPL4 PF05021.15 CAR23634.1 - 2.2e-129 431.2 0.0 2.9e-129 430.8 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CAR23634.1 - 1.4e-68 229.6 0.3 2.3e-68 228.9 0.3 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CAR23634.1 - 0.0014 19.1 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.20 CAR23635.1 - 1.3e-188 628.0 3.0 1.3e-188 628.0 3.0 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CAR23635.1 - 8.9e-13 47.7 0.4 3.6e-12 45.7 0.2 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CAR23635.1 - 0.00048 20.5 2.7 0.0027 18.1 0.1 3.1 3 1 0 3 3 3 1 Cell division protein FtsA Trans_reg_C PF00486.28 CAR23635.1 - 0.019 15.0 0.0 0.075 13.1 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal NLE PF08154.12 CAR23635.1 - 0.02 15.4 0.4 0.13 12.8 0.1 2.6 3 0 0 3 3 3 0 NLE (NUC135) domain Raco_middle PF17651.1 CAR23635.1 - 0.091 12.4 0.3 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 RACo middle region Endonuc_Holl PF10107.9 CAR23635.1 - 0.58 10.0 5.4 0.17 11.7 0.2 2.5 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Oxidored-like PF09791.9 CAR23636.1 - 3.1e-25 87.6 3.2 6.5e-25 86.5 3.2 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Pex24p PF06398.11 CAR23637.1 - 2.1e-46 158.6 4.1 2.4e-46 158.4 4.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpp20 PF12328.8 CAR23638.1 - 5.4e-26 91.2 7.1 9.1e-24 84.0 7.1 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CAR23638.1 - 1e-08 34.9 0.2 1.7e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Alba PriC PF07445.12 CAR23639.1 - 0.054 13.4 5.6 0.12 12.3 5.6 1.9 1 1 0 1 1 1 0 Primosomal replication protein priC Ureidogly_lyase PF04115.12 CAR23640.1 - 2.4e-52 177.4 0.0 2.8e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase PDH PF02153.17 CAR23641.1 - 4.9e-09 35.6 0.0 8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 CAR23641.1 - 2.5e-05 24.5 0.0 4.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CAR23641.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 CAR23641.1 - 0.00012 21.4 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CAR23641.1 - 0.00024 21.6 0.0 0.00052 20.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CAR23641.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CAR23641.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 CAR23641.1 - 0.075 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Arf PF00025.21 CAR23643.1 - 2.1e-74 248.7 0.0 2.4e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAR23643.1 - 4e-15 56.1 0.0 5.4e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAR23643.1 - 6.5e-11 42.0 0.0 7.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CAR23643.1 - 2e-10 40.4 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CAR23643.1 - 2.8e-10 40.1 0.0 3.2e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAR23643.1 - 5.3e-10 39.0 0.1 1.2e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CAR23643.1 - 0.00076 19.5 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CAR23643.1 - 0.0058 17.1 0.1 0.011 16.2 0.1 1.6 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 CAR23643.1 - 0.01 14.8 0.2 0.42 9.6 0.1 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CAR23643.1 - 0.065 13.8 0.2 0.11 13.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 CAR23643.1 - 0.25 10.9 0.5 9 5.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC1 PF03109.16 CAR23644.1 - 2.9e-17 62.9 0.0 7.6e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CAR23644.1 - 0.04 13.9 0.2 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Meiotic_rec114 PF03525.14 CAR23644.1 - 0.18 10.7 0.1 0.31 10.0 0.1 1.3 1 0 0 1 1 1 0 Meiotic recombination protein rec114 GDPD PF03009.17 CAR23645.1 - 5.8e-78 262.2 0.0 1.1e-77 261.3 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CAR23645.1 - 2e-24 86.0 0.1 9.7e-15 54.9 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) SPX PF03105.19 CAR23645.1 - 1.4e-20 74.6 30.5 4.7e-11 43.2 2.0 4.5 2 1 2 4 4 4 3 SPX domain Ank_4 PF13637.6 CAR23645.1 - 1.6e-14 54.0 0.0 2.9e-06 27.7 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR23645.1 - 2.2e-14 53.3 0.0 0.00023 21.4 0.0 4.9 2 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR23645.1 - 3.9e-12 45.2 0.8 0.61 10.8 0.0 7.5 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 CAR23645.1 - 7.1e-09 35.7 0.4 2.6 8.6 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat GGA_N-GAT PF18308.1 CAR23645.1 - 2.2 8.0 4.6 1.2 8.8 1.0 2.5 2 0 0 2 2 2 0 GGA N-GAT domain AMP-binding PF00501.28 CAR23647.1 - 1.5e-87 293.9 0.1 2.2e-87 293.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR23647.1 - 0.00014 22.8 0.0 0.00036 21.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_1 PF00561.20 CAR23648.1 - 5.6e-23 81.9 0.5 7.1e-23 81.6 0.5 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR23648.1 - 2.5e-16 61.0 0.0 4e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR23648.1 - 1.6e-11 44.0 0.0 6e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 CAR23648.1 - 8.7e-05 22.3 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 CAR23648.1 - 0.00051 19.9 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 CAR23648.1 - 0.012 15.1 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase zf-RING_2 PF13639.6 CAR23650.1 - 2.2e-07 31.1 7.1 7e-07 29.5 7.1 2.0 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CAR23650.1 - 7.5e-06 26.0 3.9 2.2e-05 24.5 3.9 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 CAR23650.1 - 0.0001 22.5 6.1 0.00024 21.3 6.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR23650.1 - 0.0015 18.5 1.7 0.0033 17.5 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 CAR23650.1 - 0.011 16.0 6.5 0.028 14.7 6.5 1.8 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 CAR23650.1 - 0.041 14.0 5.1 0.083 13.0 5.1 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 CAR23650.1 - 0.11 12.4 4.8 1.1 9.2 4.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CAR23650.1 - 0.11 12.1 3.6 0.25 11.0 3.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CAR23650.1 - 0.29 11.0 10.7 0.054 13.3 6.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR23650.1 - 0.81 9.6 12.6 0.11 12.4 6.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CAR23650.1 - 1.2 9.3 2.9 17 5.6 0.6 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 CAR23650.1 - 1.5 8.7 6.7 49 3.8 6.5 2.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 CAR23650.1 - 1.9 8.5 5.2 4 7.4 5.2 1.6 1 0 0 1 1 1 0 PHD-finger Mannosyl_trans3 PF11051.8 CAR23651.1 - 0.0013 18.2 0.4 0.0021 17.4 0.4 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative RRM_1 PF00076.22 CAR23652.1 - 3.1e-27 94.2 0.1 1.7e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR23652.1 - 0.00014 21.4 0.0 0.001 18.6 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR23652.1 - 0.012 15.6 0.1 0.029 14.4 0.0 1.7 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CAR23652.1 - 0.04 14.0 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 CAR23652.1 - 0.074 13.3 0.4 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter SAM_decarbox PF01536.16 CAR23653.1 - 4.3e-133 443.7 0.2 4.9e-133 443.5 0.2 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pyridoxal_deC PF00282.19 CAR23654.1 - 1.4e-54 185.3 0.0 2.2e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OKR_DC_1 PF01276.20 CAR23654.1 - 0.051 12.3 0.0 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Recep_L_domain PF01030.24 CAR23656.1 - 8.1e-11 42.0 8.0 0.0026 17.8 0.1 4.6 1 1 3 4 4 4 4 Receptor L domain Bacteriocin_IIc PF10439.9 CAR23656.1 - 0.0027 17.8 0.4 0.93 9.7 0.1 3.9 2 1 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide LRR_9 PF14580.6 CAR23656.1 - 0.02 14.4 1.8 0.039 13.4 1.2 1.7 1 1 0 1 1 1 0 Leucine-rich repeat PH_14 PF17787.1 CAR23656.1 - 0.034 14.0 0.3 0.38 10.6 0.0 2.4 2 1 0 2 2 2 0 PH domain LRR_4 PF12799.7 CAR23656.1 - 9.3 6.8 26.1 0.44 11.1 6.1 5.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) GLTP PF08718.11 CAR23657.1 - 5.5e-49 166.3 0.3 1.1e-48 165.3 0.1 1.6 2 1 0 2 2 2 1 Glycolipid transfer protein (GLTP) PCI PF01399.27 CAR23658.1 - 9.9e-07 29.2 0.7 2.3e-05 24.8 0.0 3.0 2 0 0 2 2 2 1 PCI domain NARG2_C PF10505.9 CAR23658.1 - 0.095 12.2 4.8 2.3 7.7 0.0 3.7 4 0 0 4 4 4 0 NMDA receptor-regulated gene protein 2 C-terminus AAA PF00004.29 CAR23659.1 - 3.3e-51 173.1 0.0 2.9e-38 131.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR23659.1 - 2.7e-10 39.9 0.0 6.6e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 CAR23659.1 - 6.7e-10 38.6 1.6 1.9e-09 37.2 0.4 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 CAR23659.1 - 2.5e-09 37.5 0.5 0.00014 22.2 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAR23659.1 - 3.9e-09 37.1 0.2 0.0024 18.2 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 CAR23659.1 - 1.6e-07 30.9 0.4 0.017 14.3 0.1 2.6 2 1 1 3 3 3 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR23659.1 - 2.1e-06 27.3 0.1 0.0033 16.8 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CAR23659.1 - 2.6e-06 27.6 0.0 0.095 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CAR23659.1 - 1.5e-05 24.9 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 CAR23659.1 - 1.5e-05 25.0 0.1 0.0044 17.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.16 CAR23659.1 - 1.8e-05 24.3 0.0 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein CDC48_N PF02359.18 CAR23659.1 - 2.1e-05 24.6 0.0 7.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TsaE PF02367.17 CAR23659.1 - 5.2e-05 23.2 0.0 0.46 10.5 0.0 3.3 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 CAR23659.1 - 6.9e-05 23.0 0.0 0.0015 18.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 CAR23659.1 - 7.9e-05 22.5 0.2 0.47 10.2 0.1 3.1 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 CAR23659.1 - 9.2e-05 22.4 4.6 0.16 11.9 0.1 3.7 4 1 0 4 4 3 2 NACHT domain RuvB_N PF05496.12 CAR23659.1 - 9.4e-05 22.2 0.3 0.14 11.8 0.1 2.9 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 CAR23659.1 - 9.8e-05 21.7 0.0 0.15 11.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 CAR23659.1 - 0.00012 21.8 0.0 0.43 10.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_30 PF13604.6 CAR23659.1 - 0.00019 21.2 0.0 0.33 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CAR23659.1 - 0.00022 21.8 1.2 0.049 14.1 0.1 2.6 2 0 0 2 2 2 1 ABC transporter ResIII PF04851.15 CAR23659.1 - 0.00024 21.2 0.0 0.18 11.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CAR23659.1 - 0.00038 20.8 0.0 0.25 11.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 CAR23659.1 - 0.00061 19.8 0.0 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CAR23659.1 - 0.00063 19.1 0.1 0.27 10.4 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 CAR23659.1 - 0.00085 19.2 0.0 0.09 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 CAR23659.1 - 0.00098 19.0 0.0 0.43 10.4 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_7 PF12775.7 CAR23659.1 - 0.00098 18.7 0.1 0.12 11.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 CAR23659.1 - 0.0011 19.6 1.2 0.62 10.5 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR23659.1 - 0.0018 18.8 0.0 0.97 10.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CAR23659.1 - 0.007 15.8 0.1 4.8 6.5 0.1 3.2 2 1 0 2 2 2 0 Bacterial TniB protein ATPase PF06745.13 CAR23659.1 - 0.011 15.1 1.1 0.45 9.8 0.1 2.9 3 0 0 3 3 3 0 KaiC AAA_19 PF13245.6 CAR23659.1 - 0.015 15.7 0.2 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CAR23659.1 - 0.025 13.6 0.0 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.11 CAR23659.1 - 0.026 14.4 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CAR23659.1 - 0.041 13.6 0.4 2.7 7.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CAR23659.1 - 0.069 12.7 0.2 15 5.1 0.0 2.8 3 0 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 CAR23659.1 - 0.091 12.5 0.1 8.1 6.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase ATPase_2 PF01637.18 CAR23659.1 - 0.098 12.6 0.5 7.9 6.3 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 CAR23659.1 - 0.12 12.6 0.0 7.8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CAR23659.1 - 0.18 10.9 0.0 14 4.7 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Yos9_DD PF17880.1 CAR23661.1 - 7.9e-15 55.1 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Yos9 dimerzation domain PRKCSH PF07915.13 CAR23661.1 - 3.2e-06 28.1 0.3 8.4e-06 26.7 0.3 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Bromodomain PF00439.25 CAR23662.1 - 7.7e-18 64.3 0.7 2.8e-17 62.5 0.7 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CAR23662.1 - 0.00023 21.1 0.0 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated RRP7 PF12923.7 CAR23662.1 - 0.0075 16.4 5.2 0.0075 16.4 5.2 3.1 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain UQ_con PF00179.26 CAR23663.1 - 2e-52 176.6 0.0 2.2e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR23663.1 - 0.0011 19.2 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CAR23663.1 - 0.005 16.5 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CAR23663.1 - 0.019 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain CBF PF03914.17 CAR23664.1 - 9.1e-48 162.5 0.4 9.1e-48 162.5 0.4 3.5 3 0 0 3 3 3 1 CBF/Mak21 family zf-H3C2 PF16721.5 CAR23664.1 - 0.42 11.0 2.7 3.3 8.1 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger like, probable DNA-binding TEA PF01285.18 CAR23665.1 - 7.1e-21 74.1 0.2 1.2e-20 73.3 0.2 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Herpes_pp85 PF04637.12 CAR23665.1 - 0.24 9.8 1.8 0.38 9.1 1.8 1.4 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FTHFS PF01268.19 CAR23666.1 - 3.5e-253 840.9 2.4 4.4e-253 840.5 2.4 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CAR23666.1 - 5.8e-67 224.0 2.6 6.3e-67 223.9 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CAR23666.1 - 4.6e-36 123.6 1.1 1.6e-35 121.8 0.5 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain PBP-Tp47_a PF14889.6 CAR23666.1 - 0.043 13.5 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Spiralin PF05215.13 CAR23666.1 - 0.045 13.1 1.7 0.1 11.9 1.7 1.5 1 0 0 1 1 1 0 Spiralin DUF43 PF01861.16 CAR23666.1 - 0.11 11.7 0.0 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Branched-chain polyamine synthase A C-terminal domain Ribosomal_L19e PF01280.20 CAR23667.1 - 1.4e-58 197.1 11.3 1.4e-58 197.1 11.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.9 CAR23668.1 - 1.1e-16 60.8 11.0 1.1e-16 60.8 11.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) DnaG_DnaB_bind PF08278.11 CAR23668.1 - 0.069 13.7 4.0 0.11 13.1 4.0 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding ZapB PF06005.12 CAR23668.1 - 2.7 8.5 13.3 0.51 10.8 8.1 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Exonuc_VII_L PF02601.15 CAR23668.1 - 3.9 7.0 9.4 4.4 6.8 9.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit PI3K_1B_p101 PF10486.9 CAR23669.1 - 0.33 8.7 2.0 0.39 8.4 2.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 CAR23669.1 - 3.1 7.5 7.3 0.45 10.2 3.0 1.7 2 0 0 2 2 2 0 FAM176 family Zn_clus PF00172.18 CAR23670.1 - 6.5e-08 32.6 15.6 1.9e-07 31.1 15.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR23670.1 - 5.2e-07 29.0 1.5 1.1e-06 27.9 1.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mito_carr PF00153.27 CAR23671.1 - 1.1e-66 220.7 6.8 1.6e-23 82.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Msap1 PF17077.5 CAR23672.1 - 1e-34 120.2 16.8 1e-34 120.2 16.8 1.9 1 1 0 1 1 1 1 Mitotic spindle associated protein SHE1 IHABP4_N PF16174.5 CAR23672.1 - 1.7 9.3 11.1 8.4 7.0 0.5 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal KH_1 PF00013.29 CAR23673.1 - 1.9e-36 123.7 6.6 1e-13 50.9 0.0 3.1 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CAR23673.1 - 1.3e-07 31.3 4.0 0.022 14.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CAR23673.1 - 9.7e-07 28.6 2.9 0.36 10.7 0.1 3.6 3 1 1 4 4 4 3 KH domain KH_5 PF13184.6 CAR23673.1 - 0.0015 18.6 6.0 1 9.5 0.4 3.4 3 0 0 3 3 3 2 NusA-like KH domain GTP_cyclohydro2 PF00925.20 CAR23674.1 - 5.9e-57 191.8 0.0 8.4e-57 191.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II CLASP_N PF12348.8 CAR23676.1 - 1.6e-77 260.1 2.8 9.7e-71 237.9 0.2 2.6 2 0 0 2 2 2 2 CLASP N terminal Pol_alpha_B_N PF08418.10 CAR23677.1 - 3.1e-60 204.2 0.3 4.1e-60 203.8 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CAR23677.1 - 3.5e-45 153.9 0.0 5e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Anoctamin PF04547.12 CAR23678.1 - 1.9e-46 158.9 22.7 5.8e-46 157.2 22.7 1.7 1 1 0 1 1 1 1 Calcium-activated chloride channel Pho86 PF11124.8 CAR23678.1 - 0.0031 17.0 0.7 0.012 15.2 0.1 2.1 2 0 0 2 2 2 1 Inorganic phosphate transporter Pho86 Ala_racemase_N PF01168.20 CAR23679.1 - 2.5e-20 73.1 0.0 2.9e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain PEP-utilisers_N PF05524.13 CAR23679.1 - 0.065 13.4 0.0 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Adaptin_N PF01602.20 CAR23680.1 - 8.4e-104 348.0 17.9 8.4e-104 348.0 17.9 1.3 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CAR23680.1 - 1.8e-05 24.9 0.0 4.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain RLAN PF14401.6 CAR23680.1 - 0.0017 18.0 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATPgrasp N-terminal domain Alpha_adaptinC2 PF02883.20 CAR23680.1 - 0.0019 18.5 0.0 0.0046 17.3 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain RPT PF13446.6 CAR23680.1 - 0.0053 16.7 0.0 0.027 14.4 0.0 2.2 2 0 0 2 2 2 1 A repeated domain in UCH-protein HEAT PF02985.22 CAR23680.1 - 0.069 13.4 1.6 1.9 9.0 0.1 3.7 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 CAR23680.1 - 0.15 12.1 1.2 3.9 7.7 0.4 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DNA_pol3_delta2 PF13177.6 CAR23681.1 - 2.7e-11 43.5 0.2 2.5e-10 40.4 0.2 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CAR23681.1 - 1e-06 29.2 0.0 2.6e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 CAR23681.1 - 0.0012 19.2 0.3 0.0028 17.9 0.1 1.7 2 0 0 2 2 2 1 AAA C-terminal domain Rad17 PF03215.15 CAR23681.1 - 0.002 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Rep_fac_C PF08542.11 CAR23681.1 - 0.0068 16.8 0.3 0.023 15.1 0.0 2.0 3 0 0 3 3 3 1 Replication factor C C-terminal domain AAA_16 PF13191.6 CAR23681.1 - 0.029 14.8 0.0 0.21 12.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain Nterm_IS4 PF13006.7 CAR23681.1 - 0.071 13.3 0.0 0.33 11.2 0.0 2.0 1 1 1 2 2 2 0 Insertion element 4 transposase N-terminal DNA_pol3_delta PF06144.13 CAR23681.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Ribosomal_L16 PF00252.18 CAR23682.1 - 4.1e-37 127.1 0.1 5.3e-37 126.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.20 CAR23683.1 - 3e-43 148.1 0.1 1e-24 87.4 0.0 2.6 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CAR23683.1 - 1.3e-26 92.9 0.2 8.8e-26 90.2 0.0 2.2 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain FAD_binding_1 PF00667.20 CAR23684.1 - 2.1e-28 99.4 0.0 3.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CAR23684.1 - 4.9e-19 69.0 0.0 1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CAR23684.1 - 5.3e-11 43.1 0.0 1.3e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ATG11 PF10377.9 CAR23685.1 - 1.9e-37 128.2 0.1 1.9e-37 128.2 0.1 3.0 3 0 0 3 3 3 1 Autophagy-related protein 11 TPR_MLP1_2 PF07926.12 CAR23685.1 - 0.00023 21.2 32.1 0.0012 18.9 14.8 4.9 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 CAR23685.1 - 0.069 13.4 11.7 0.022 15.0 3.7 4.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) TRPM_tetra PF16519.5 CAR23685.1 - 0.55 10.4 12.3 0.42 10.7 0.5 4.2 4 0 0 4 4 4 0 Tetramerisation domain of TRPM Peptidase_M3_N PF08439.10 CAR23685.1 - 3 8.2 7.6 7.3 7.0 0.2 4.2 4 0 0 4 4 4 0 Oligopeptidase F DUF1664 PF07889.12 CAR23685.1 - 3.4 7.7 23.6 2.3 8.3 1.2 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Acetyltransf_1 PF00583.25 CAR23686.1 - 3.4e-20 72.4 0.1 4.3e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR23686.1 - 2.4e-12 46.9 0.1 3.5e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR23686.1 - 2.8e-12 46.9 0.1 3.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR23686.1 - 4.9e-10 39.3 0.1 7.5e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CAR23686.1 - 1.6e-05 25.0 0.0 3.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CAR23686.1 - 2.5e-05 25.0 0.0 2.9e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CAR23686.1 - 0.0002 21.1 0.0 0.00029 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CAR23686.1 - 0.00024 21.2 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CAR23686.1 - 0.0035 17.3 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase Acetyltransf_4 PF13420.7 CAR23686.1 - 0.0038 17.4 0.1 0.0044 17.2 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 CAR23686.1 - 0.0042 16.8 0.1 0.0059 16.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_15 PF17013.5 CAR23686.1 - 0.0043 16.5 0.1 0.0078 15.7 0.1 1.6 1 1 0 1 1 1 1 Putative acetyl-transferase PCNA_N PF00705.18 CAR23687.1 - 1.7e-52 176.5 3.3 4.3e-52 175.1 1.6 2.2 2 1 1 3 3 3 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CAR23687.1 - 3.9e-49 166.1 0.2 8.7e-49 164.9 0.1 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CAR23687.1 - 8.7e-05 21.7 0.1 0.00036 19.7 0.1 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CAR23687.1 - 0.0089 15.5 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Rad9 Phyto-Amp PF15438.6 CAR23687.1 - 0.075 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma FAD-oxidase_C PF02913.19 CAR23687.1 - 0.19 11.3 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain HMG_box PF00505.19 CAR23688.1 - 3.4e-24 85.0 0.4 5.7e-24 84.3 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR23688.1 - 3.2e-16 59.7 0.4 4.9e-16 59.1 0.4 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 CAR23688.1 - 0.00085 19.9 0.7 0.003 18.1 0.0 1.9 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 CAR23688.1 - 0.0049 16.8 0.0 0.0074 16.2 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain zf-Tim10_DDP PF02953.15 CAR23689.1 - 2.5e-14 52.7 0.1 3e-14 52.4 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.15 CAR23690.1 - 2e-73 247.1 0.3 3.3e-73 246.4 0.3 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 CAR23690.1 - 8.1e-44 149.7 0.0 1.3e-43 149.1 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 CAR23690.1 - 0.004 16.5 0.0 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 YheC/D like ATP-grasp Fibroin_P25 PF07294.11 CAR23690.1 - 0.023 14.7 0.4 0.094 12.8 0.0 1.9 2 0 0 2 2 2 0 Fibroin P25 RXT2_N PF08595.11 CAR23691.1 - 2.9e-33 115.1 1.1 6.3e-31 107.5 1.1 2.5 1 1 0 1 1 1 1 RXT2-like, N-terminal DUF2786 PF10979.8 CAR23691.1 - 0.14 12.1 0.9 0.38 10.7 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) TLE_N PF03920.15 CAR23692.1 - 0.008 16.3 0.1 0.008 16.3 0.1 2.4 2 0 0 2 2 2 1 Groucho/TLE N-terminal Q-rich domain Ccdc124 PF06244.12 CAR23692.1 - 3.8 8.1 12.7 1.8 9.1 8.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 124 /Oxs1 4HBT_2 PF13279.6 CAR23693.1 - 4.2e-08 33.7 0.0 6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.25 CAR23694.1 - 7.7e-62 209.0 0.0 9.5e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23694.1 - 4e-29 101.7 0.0 5.8e-29 101.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR23694.1 - 0.002 17.1 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAR23694.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CAR23694.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 CAR23695.1 - 2.2e-21 76.4 0.1 7.4e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain HEAT PF02985.22 CAR23695.1 - 5.4e-09 35.5 2.4 0.62 10.5 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.17 CAR23695.1 - 5.5e-07 29.1 0.0 9.2e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 CAR23695.1 - 0.00022 21.6 0.0 0.52 10.7 0.0 3.2 2 1 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 CAR23695.1 - 0.016 15.3 3.6 2.8 8.0 0.3 3.4 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CAR23695.1 - 0.018 15.5 0.0 2.1 8.9 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat APH PF01636.23 CAR23695.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NHL PF01436.21 CAR23695.1 - 0.13 12.4 0.2 0.51 10.5 0.2 2.1 2 0 0 2 2 2 0 NHL repeat WD40 PF00400.32 CAR23695.1 - 0.19 12.6 1.0 0.78 10.7 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat M11L PF11099.8 CAR23695.1 - 0.25 11.6 7.0 6.7 7.0 1.6 2.7 2 0 0 2 2 2 0 Apoptosis regulator M11L like Sec8_exocyst PF04048.14 CAR23696.1 - 1.1e-47 161.5 3.2 1.1e-47 161.5 3.2 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CAR23696.1 - 6.9e-06 25.6 0.9 6.9e-06 25.6 0.9 2.8 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex Vps51 PF08700.11 CAR23696.1 - 0.026 14.6 10.3 0.76 9.9 0.1 5.4 5 2 0 5 5 5 0 Vps51/Vps67 Peptidase_C101 PF16218.5 CAR23696.1 - 0.039 13.2 1.0 0.2 10.9 0.2 2.5 3 0 0 3 3 3 0 Peptidase family C101 Pkip-1 PF06878.11 CAR23696.1 - 0.086 12.9 3.0 0.18 11.9 0.5 2.6 2 0 0 2 2 2 0 Pkip-1 protein BLOC1S3 PF15753.5 CAR23696.1 - 1.9 8.6 6.9 0.44 10.7 2.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 PCRF PF03462.18 CAR23696.1 - 3.1 7.6 5.7 0.71 9.7 1.0 2.4 3 0 0 3 3 3 0 PCRF domain ERCC4 PF02732.15 CAR23697.1 - 1.3e-09 38.4 0.3 3e-09 37.3 0.3 1.7 1 0 0 1 1 1 1 ERCC4 domain T3RM_EcoP15I_C PF18273.1 CAR23697.1 - 0.0034 17.7 0.2 0.33 11.3 0.1 2.9 2 0 0 2 2 2 1 Type III R-M EcoP15I C-terminal domain Fes1 PF08609.10 CAR23698.1 - 7.3e-23 81.3 1.7 4e-22 78.9 0.6 2.6 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 CAR23698.1 - 3.9e-05 24.0 0.2 0.0015 18.9 0.0 3.0 1 1 2 3 3 3 1 HEAT repeats Atx10homo_assoc PF09759.9 CAR23698.1 - 5.5e-05 23.1 0.1 0.0016 18.4 0.0 2.1 2 1 1 3 3 3 2 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 CAR23698.1 - 0.00087 19.4 0.2 0.46 10.9 0.0 3.3 3 0 0 3 3 3 1 HEAT repeat V-ATPase_H_C PF11698.8 CAR23698.1 - 0.0037 17.4 0.9 1.3 9.1 0.2 2.6 1 1 1 2 2 2 2 V-ATPase subunit H Cnd1 PF12717.7 CAR23698.1 - 0.014 15.4 1.3 4.5 7.3 0.1 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CAR23698.1 - 0.05 13.7 0.0 13 6.0 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CAR23698.1 - 0.085 13.4 0.0 20 5.8 0.0 3.2 3 0 0 3 3 3 0 HEAT-like repeat UFD1 PF03152.14 CAR23699.1 - 8.1e-10 38.4 0.0 9.9e-05 21.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 CAR23699.1 - 2.6e-06 27.6 0.2 2.6e-06 27.6 0.2 2.1 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-ribbon_3 PF13248.6 CAR23699.1 - 0.47 9.9 7.5 1.6 8.2 0.2 3.9 3 0 0 3 3 3 0 zinc-ribbon domain Exo84_C PF16528.5 CAR23700.1 - 4.2e-52 177.0 6.4 4.2e-52 177.0 6.4 1.9 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CAR23700.1 - 3.2e-10 39.9 1.3 1.2e-09 38.1 1.3 2.1 1 0 0 1 1 1 1 Vps51/Vps67 ANAPC4 PF12896.7 CAR23700.1 - 0.38 10.2 6.1 0.54 9.7 0.2 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF2524 PF10732.9 CAR23700.1 - 1.5 9.2 11.7 5.9 7.3 0.5 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2524) WD40 PF00400.32 CAR23701.1 - 4.2e-20 71.7 13.3 2.1e-06 28.4 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23701.1 - 2.1e-10 40.7 0.5 7e-05 23.0 0.1 5.3 3 2 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CAR23701.1 - 1.3e-06 28.1 0.2 2.3e-06 27.3 0.2 1.4 1 0 0 1 1 1 1 LisH WD40_like PF17005.5 CAR23701.1 - 2.9e-05 23.6 0.1 0.012 14.9 0.0 3.1 2 2 1 3 3 3 2 WD40-like domain eIF2A PF08662.11 CAR23701.1 - 0.00013 21.9 1.2 0.0025 17.7 0.2 3.0 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A SdiA-regulated PF06977.11 CAR23701.1 - 0.018 14.3 0.2 1.1 8.4 0.0 3.4 4 0 0 4 4 4 0 SdiA-regulated RAB3GAP2_N PF14655.6 CAR23701.1 - 0.025 13.8 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Tfb4 PF03850.14 CAR23702.1 - 1.9e-106 355.6 0.1 2.2e-106 355.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 CRPA PF05745.11 CAR23702.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) FEZ PF07763.13 CAR23702.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 FEZ-like protein Rad50_zn_hook PF04423.14 CAR23702.1 - 0.29 11.0 1.5 0.59 10.0 0.3 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif SIP1 PF04938.12 CAR23703.1 - 9.3e-09 35.3 0.1 1.6e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Mito_carr PF00153.27 CAR23704.1 - 1.7e-60 200.9 1.8 1.4e-20 73.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.21 CAR23705.1 - 0.0072 16.7 0.1 0.49 10.8 0.1 2.8 2 1 0 2 2 2 1 Chorismate mutase type II DnaJ PF00226.31 CAR23706.1 - 2e-11 43.9 0.2 1.2e-09 38.1 0.2 2.5 1 1 0 1 1 1 1 DnaJ domain dCMP_cyt_deam_1 PF00383.23 CAR23707.1 - 9.4e-21 73.6 0.0 1.3e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR23707.1 - 1.7e-17 63.4 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase NAD1 PF18778.1 CAR23707.1 - 1.1e-05 25.6 0.0 0.014 15.5 0.0 2.1 2 0 0 2 2 2 2 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 CAR23707.1 - 0.00015 21.9 0.1 0.061 13.4 0.0 2.1 2 0 0 2 2 2 2 APOBEC2 SNAD4 PF18750.1 CAR23707.1 - 0.00019 21.5 0.0 0.00092 19.3 0.0 1.9 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 CAR23707.1 - 0.0022 17.9 0.3 0.4 10.6 0.1 2.1 1 1 1 2 2 2 2 APOBEC-like N-terminal domain NAD2 PF18782.1 CAR23707.1 - 0.0039 17.3 0.1 0.22 11.6 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 CAR23707.1 - 0.004 17.2 0.8 0.06 13.4 0.5 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC4_like PF18774.1 CAR23707.1 - 0.0078 16.2 0.1 0.061 13.3 0.1 2.1 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase UPF0139 PF03669.13 CAR23708.1 - 0.00024 20.9 0.3 0.0003 20.6 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Vac_ImportDeg PF09783.9 CAR23709.1 - 5.3e-59 198.7 0.0 6.6e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein ThrE PF06738.12 CAR23710.1 - 1.2e-68 231.0 18.8 1.5e-65 220.9 5.7 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CAR23710.1 - 3.9e-12 46.4 11.2 3.9e-12 46.4 11.2 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE BP28CT PF08146.12 CAR23711.1 - 7.9e-39 133.0 1.3 6.3e-38 130.1 1.3 2.8 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CAR23711.1 - 1.6e-18 67.1 0.6 1.6e-18 67.1 0.6 5.1 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 CAR23711.1 - 0.0011 19.3 0.1 6.1 7.3 0.0 4.3 5 0 0 5 5 5 2 HEAT repeats HEAT PF02985.22 CAR23711.1 - 0.0036 17.4 0.6 8.1 7.0 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat UNC-50 PF05216.13 CAR23712.1 - 4.4e-88 294.5 20.4 4.9e-88 294.4 20.4 1.0 1 0 0 1 1 1 1 UNC-50 family ssDBP PF17878.1 CAR23713.1 - 0.18 12.0 0.2 0.47 10.7 0.2 1.7 1 1 0 1 1 1 0 Single-stranded DNA-binding protein DUF1690 PF07956.11 CAR23714.1 - 4.7 7.6 7.2 0.9 10.0 0.1 3.0 4 0 0 4 4 4 0 Protein of Unknown function (DUF1690) PLDc PF00614.22 CAR23715.1 - 5.9e-15 54.7 3.3 1.7e-07 31.1 0.3 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CAR23715.1 - 4.2e-11 42.9 0.1 6.4e-06 26.1 0.0 3.2 4 0 0 4 4 4 2 PLD-like domain PX PF00787.24 CAR23715.1 - 9.8e-07 28.8 4.3 0.0057 16.6 0.2 3.7 3 0 0 3 3 3 2 PX domain GATA PF00320.27 CAR23716.1 - 6.6e-15 54.4 4.7 1.4e-14 53.4 4.7 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CAR23716.1 - 0.0017 17.8 0.2 0.0029 17.1 0.2 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding ArfGap PF01412.18 CAR23716.1 - 0.21 11.7 0.5 0.56 10.3 0.1 1.8 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Snf7 PF03357.21 CAR23717.1 - 2.7e-10 40.1 18.4 3.6e-10 39.7 18.4 1.2 1 0 0 1 1 1 1 Snf7 BORCS7 PF16088.5 CAR23717.1 - 0.036 14.3 5.7 0.047 14.0 0.7 2.5 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 Scm3 PF10384.9 CAR23717.1 - 0.13 12.0 0.2 0.13 12.0 0.2 2.4 2 0 0 2 2 2 0 Centromere protein Scm3 SurA_N PF09312.11 CAR23717.1 - 0.48 10.5 8.0 1.1 9.3 1.5 2.9 2 1 0 2 2 2 0 SurA N-terminal domain DMSP_lyase PF16867.5 CAR23717.1 - 0.53 9.9 0.1 0.53 9.9 0.1 2.3 3 0 0 3 3 3 0 Dimethlysulfonioproprionate lyase ECH_2 PF16113.5 CAR23717.1 - 0.61 9.5 10.5 0.28 10.6 7.8 1.7 1 1 1 2 2 2 0 Enoyl-CoA hydratase/isomerase CPSase_L_D3 PF02787.19 CAR23717.1 - 0.87 9.9 6.3 1.4 9.3 1.8 2.2 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain APG6_N PF17675.1 CAR23717.1 - 1.1 9.8 16.6 1.3 9.5 7.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF948 PF06103.11 CAR23717.1 - 2.1 8.7 9.6 3.3 8.0 2.5 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Aldo_ket_red PF00248.21 CAR23718.1 - 2.6e-47 161.4 0.0 2e-38 132.3 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Cpn60_TCP1 PF00118.24 CAR23719.1 - 1.6e-154 515.2 4.9 1.8e-154 515.0 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 CAR23719.1 - 0.17 12.4 0.0 0.42 11.1 0.0 1.6 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch WD40 PF00400.32 CAR23720.1 - 1.7e-30 104.6 8.0 1e-06 29.4 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Mdv1 PF11542.8 CAR23720.1 - 3.8e-07 30.0 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial division protein 1 ANAPC4_WD40 PF12894.7 CAR23720.1 - 9e-07 29.1 0.0 0.71 10.2 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR23720.1 - 1.3e-06 27.4 4.7 0.00066 18.4 0.0 4.4 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Caf4 PF11615.8 CAR23720.1 - 0.0022 17.9 0.3 0.66 10.0 0.1 3.0 2 0 0 2 2 2 1 CCR4-associated factor 4 BBS2_Mid PF14783.6 CAR23720.1 - 0.0029 17.6 0.4 0.2 11.7 0.0 3.3 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Cwf_Cwc_15 PF04889.12 CAR23720.1 - 0.79 9.4 8.4 1.4 8.6 8.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DASH_Spc34 PF08657.10 CAR23721.1 - 2.1e-82 276.8 3.9 4e-82 275.8 3.9 1.4 1 1 0 1 1 1 1 DASH complex subunit Spc34 Occludin_ELL PF07303.13 CAR23721.1 - 0.031 15.0 0.5 0.078 13.7 0.5 1.7 1 0 0 1 1 1 0 Occludin homology domain OmpH PF03938.14 CAR23721.1 - 0.036 14.4 3.8 0.036 14.4 3.8 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TetR_C_4 PF08359.11 CAR23721.1 - 0.081 13.1 0.2 0.42 10.8 0.0 2.3 1 1 1 2 2 2 0 YsiA-like protein, C-terminal region V_ATPase_I PF01496.19 CAR23721.1 - 0.13 10.1 0.9 0.2 9.5 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.6 CAR23721.1 - 0.19 11.4 8.8 0.029 14.0 5.0 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 CAR23721.1 - 0.21 11.5 3.9 12 5.9 0.1 2.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 CAR23721.1 - 3.5 8.0 10.3 3.9 7.9 0.2 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Peptidase_M22 PF00814.25 CAR23722.1 - 3.2e-85 286.1 0.0 3.8e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF4831 PF16115.5 CAR23722.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) Carbam_trans_N PF02543.15 CAR23722.1 - 0.052 13.2 0.1 0.082 12.6 0.1 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus AA_permease PF00324.21 CAR23723.1 - 3.7e-154 513.9 40.0 4.5e-154 513.6 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23723.1 - 9.8e-42 143.3 42.4 1.3e-41 142.9 42.4 1.0 1 0 0 1 1 1 1 Amino acid permease SET PF00856.28 CAR23724.1 - 1.5e-10 41.7 1.6 1.5e-06 28.7 0.0 3.6 3 1 0 3 3 3 2 SET domain SDA1 PF05285.12 CAR23724.1 - 0.0021 17.6 23.9 0.0061 16.0 14.4 2.1 2 0 0 2 2 2 2 SDA1 Ribosomal_L4 PF00573.22 CAR23725.1 - 6.1e-44 150.0 2.3 9e-44 149.5 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CAR23725.1 - 6.6e-32 109.4 3.3 2.1e-31 107.8 1.0 2.3 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Methyltransf_25 PF13649.6 CAR23726.1 - 1.3e-11 45.0 0.0 4.9e-11 43.2 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CAR23726.1 - 1.4e-11 44.4 0.0 3e-11 43.3 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CAR23726.1 - 6.9e-10 38.9 0.0 2.2e-09 37.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR23726.1 - 3.1e-08 34.2 0.0 1.1e-07 32.4 0.0 2.0 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR23726.1 - 4.8e-08 33.0 0.0 9.6e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CAR23726.1 - 8.5e-07 28.2 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CAR23726.1 - 2.7e-05 23.6 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CAR23726.1 - 5.2e-05 22.9 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CAR23726.1 - 0.00011 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CAR23726.1 - 0.0016 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CAR23726.1 - 0.0019 18.9 0.0 0.0051 17.5 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 CAR23726.1 - 0.002 18.2 0.0 0.005 17.0 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 CAR23726.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CAR23726.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 CAR23726.1 - 0.042 13.7 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_4 PF02390.17 CAR23726.1 - 0.13 11.7 0.9 0.24 10.9 0.1 1.8 2 0 0 2 2 2 0 Putative methyltransferase Cons_hypoth95 PF03602.15 CAR23726.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PcfK PF14058.6 CAR23727.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 PcfK-like protein DER1 PF04511.15 CAR23728.1 - 0.00062 19.8 8.1 0.00099 19.1 8.1 1.3 1 0 0 1 1 1 1 Der1-like family Prefoldin PF02996.17 CAR23729.1 - 1.5e-33 115.2 2.8 2.2e-33 114.7 2.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Pox_A_type_inc PF04508.12 CAR23729.1 - 0.0013 18.5 0.3 0.012 15.4 0.1 2.5 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat SNAD4 PF18750.1 CAR23729.1 - 0.026 14.7 0.3 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Prefoldin_2 PF01920.20 CAR23729.1 - 0.082 12.9 5.8 0.14 12.1 0.9 2.4 1 1 1 2 2 2 0 Prefoldin subunit ABC_tran PF00005.27 CAR23730.1 - 1.6e-52 177.7 0.1 1.5e-26 93.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 CAR23730.1 - 5.1e-41 140.4 37.6 4e-25 88.5 12.6 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 CAR23730.1 - 1.6e-13 51.1 6.8 0.00047 20.1 0.0 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CAR23730.1 - 4.3e-10 39.7 0.4 0.00079 19.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CAR23730.1 - 4.1e-09 37.0 0.0 0.0024 18.3 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CAR23730.1 - 1.6e-08 35.0 0.0 0.011 16.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.19 CAR23730.1 - 1.7e-08 34.2 0.0 0.0046 16.4 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR23730.1 - 1.6e-07 30.9 1.4 0.011 15.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 CAR23730.1 - 1.8e-07 31.8 0.4 0.028 15.0 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_23 PF13476.6 CAR23730.1 - 1.4e-06 29.0 2.6 0.014 15.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 CAR23730.1 - 1.9e-06 28.2 0.0 0.0091 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CAR23730.1 - 5.1e-06 26.6 1.9 0.099 12.7 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 CAR23730.1 - 7.1e-06 25.3 0.2 0.0099 15.0 0.1 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.12 CAR23730.1 - 8e-06 25.9 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 CAR23730.1 - 8.4e-06 25.5 0.0 0.016 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CAR23730.1 - 1.6e-05 25.2 0.1 0.13 12.7 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 CAR23730.1 - 0.00015 21.6 0.0 0.32 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 CAR23730.1 - 0.00018 21.5 0.1 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Cytidylate_kin PF02224.18 CAR23730.1 - 0.00022 21.0 1.7 0.35 10.6 0.0 2.6 3 0 0 3 3 2 2 Cytidylate kinase AAA_24 PF13479.6 CAR23730.1 - 0.0006 19.6 0.2 0.81 9.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 CAR23730.1 - 0.0012 18.3 0.8 0.41 9.9 0.1 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_33 PF13671.6 CAR23730.1 - 0.0016 18.6 0.1 2.3 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 CAR23730.1 - 0.0018 18.1 0.2 0.31 10.7 0.1 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 CAR23730.1 - 0.0018 18.3 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CAR23730.1 - 0.0019 18.2 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CAR23730.1 - 0.0021 18.0 0.4 2.7 7.9 0.1 3.0 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.22 CAR23730.1 - 0.0022 17.2 0.0 0.51 9.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain ABC_ATPase PF09818.9 CAR23730.1 - 0.0024 16.7 0.3 0.067 12.0 0.1 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class cobW PF02492.19 CAR23730.1 - 0.0032 17.1 1.6 0.88 9.1 0.5 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 CAR23730.1 - 0.0033 17.8 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CAR23730.1 - 0.0043 17.5 0.0 3.5 8.0 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.12 CAR23730.1 - 0.0044 16.5 2.7 0.061 12.8 0.1 2.9 3 0 0 3 3 3 1 Poxvirus A32 protein KAP_NTPase PF07693.14 CAR23730.1 - 0.0055 16.0 0.0 2.5 7.3 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain SRPRB PF09439.10 CAR23730.1 - 0.0056 16.1 0.4 2.8 7.3 0.1 2.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 CAR23730.1 - 0.0058 16.3 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase MobB PF03205.14 CAR23730.1 - 0.0061 16.5 1.0 0.23 11.4 0.2 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 CAR23730.1 - 0.0061 16.3 0.0 3.8 7.1 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain dNK PF01712.19 CAR23730.1 - 0.0072 16.2 0.2 3 7.6 0.0 2.4 2 0 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 CAR23730.1 - 0.0095 15.2 0.1 1 8.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 CAR23730.1 - 0.016 15.2 0.4 3.5 7.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CAR23730.1 - 0.021 15.2 0.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CAR23730.1 - 0.025 14.4 0.8 7 6.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CAR23730.1 - 0.03 14.1 0.0 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 CAR23730.1 - 0.03 14.0 0.1 1.3 8.8 0.0 2.6 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain Septin PF00735.18 CAR23730.1 - 0.034 13.4 0.1 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Septin APS_kinase PF01583.20 CAR23730.1 - 0.044 13.7 0.8 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.17 CAR23730.1 - 0.047 13.8 6.9 4 7.5 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain Roc PF08477.13 CAR23730.1 - 0.05 13.8 0.1 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 CAR23730.1 - 0.053 13.1 1.1 0.28 10.8 0.4 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CAR23730.1 - 0.053 13.0 0.1 8 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 CAR23730.1 - 0.078 12.3 0.1 0.81 9.0 0.1 2.5 2 0 0 2 2 2 0 KaiC MeaB PF03308.16 CAR23730.1 - 0.083 11.9 0.2 0.92 8.4 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HTH_54 PF18607.1 CAR23730.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 ParA helix turn helix domain LSDAT_prok PF18171.1 CAR23730.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Dynamin_N PF00350.23 CAR23730.1 - 0.34 11.0 5.6 5.8 6.9 0.3 2.5 2 0 0 2 2 2 0 Dynamin family AAA_13 PF13166.6 CAR23730.1 - 0.74 8.4 2.9 2.8 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain zf-C2H2_12 PF18658.1 CAR23731.1 - 0.032 13.8 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type DWNN PF08783.11 CAR23731.1 - 0.1 12.9 0.2 0.68 10.3 0.1 2.3 2 0 0 2 2 2 0 DWNN domain CYSTM PF12734.7 CAR23732.1 - 0.0001 22.6 59.2 3.1e+03 -1.4 59.2 4.9 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 CAR23732.1 - 3.4 7.7 17.1 4.7 7.2 17.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) EamA PF00892.20 CAR23733.1 - 8.3e-11 42.2 22.4 1.9e-06 28.1 2.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CAR23733.1 - 1.8e-09 37.2 1.5 2.7e-09 36.6 1.5 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 CAR23733.1 - 3.9e-09 36.3 14.8 5.6e-09 35.8 14.8 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CAR23733.1 - 9.9e-08 31.5 15.3 1.3e-07 31.2 15.3 1.2 1 0 0 1 1 1 1 UAA transporter family Ilm1 PF10311.9 CAR23733.1 - 0.18 11.4 6.5 6.3 6.4 2.1 2.8 1 1 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 zf-C3HC4_2 PF13923.6 CAR23734.1 - 0.00027 20.7 0.1 0.00068 19.4 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR23734.1 - 0.0012 18.7 0.5 0.0029 17.5 0.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CAR23734.1 - 0.017 15.2 0.2 0.041 13.9 0.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR23734.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR23734.1 - 0.061 13.2 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAR23734.1 - 0.072 13.4 0.1 0.072 13.4 0.1 2.0 2 0 0 2 2 2 0 Ring finger domain IBR PF01485.21 CAR23734.1 - 0.19 12.0 2.3 3.2 8.1 0.3 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Fibrillarin PF01269.17 CAR23735.1 - 2.8e-105 350.4 0.0 3.5e-105 350.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CAR23735.1 - 3.4e-06 26.9 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CAR23735.1 - 0.011 15.9 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CAR23735.1 - 0.045 13.5 0.0 0.073 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CAR23735.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Steroid_dh PF02544.16 CAR23737.1 - 2.6e-29 102.2 9.6 2.6e-29 102.2 9.6 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Pkinase PF00069.25 CAR23738.1 - 7.9e-38 130.3 0.0 4.2e-21 75.5 0.0 3.7 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23738.1 - 4e-15 55.8 0.0 2.2e-10 40.3 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR23738.1 - 0.0027 16.5 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAR23738.1 - 0.011 15.1 0.0 3.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CAR23738.1 - 0.027 14.4 0.0 0.057 13.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CAR23738.1 - 0.027 14.1 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CAR23738.1 - 0.11 11.8 0.0 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EMP24_GP25L PF01105.24 CAR23739.1 - 9.9e-26 90.8 0.0 1.3e-25 90.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Amidohydro_1 PF01979.20 CAR23740.1 - 1.1e-36 126.9 0.0 4.8e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CAR23740.1 - 6e-13 49.1 0.1 1.1e-07 31.7 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family HEAT PF02985.22 CAR23741.1 - 6.7e-19 66.4 5.0 0.0016 18.5 0.0 9.7 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.6 CAR23741.1 - 8.3e-19 67.7 0.1 1.9e-13 50.6 0.0 6.4 7 0 0 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.6 CAR23741.1 - 3.3e-11 43.4 0.0 0.00015 22.1 0.0 5.8 6 2 1 7 7 7 2 HEAT repeats Cnd1 PF12717.7 CAR23741.1 - 1.7e-08 34.7 1.8 0.077 13.0 0.1 4.4 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CAR23741.1 - 0.0001 22.8 0.0 0.085 13.5 0.0 4.0 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CAR23741.1 - 0.028 14.6 0.4 20 5.4 0.2 4.1 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 CAR23741.1 - 0.075 13.0 1.2 0.3 11.0 1.2 2.0 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central IBN_N PF03810.19 CAR23741.1 - 0.092 12.7 2.4 1.6 8.7 0.4 3.6 2 1 0 2 2 2 0 Importin-beta N-terminal domain Glyco_hydro_42C PF08533.10 CAR23741.1 - 0.19 11.5 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain SH3_1 PF00018.28 CAR23742.1 - 2.6e-08 33.3 0.0 6.9e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR23742.1 - 0.00017 21.4 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAICAR_synt PF01259.18 CAR23743.1 - 9e-104 346.5 0.0 1e-103 346.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase UPF0086 PF01868.16 CAR23743.1 - 0.03 14.3 0.0 0.15 12.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function UPF0086 Pkinase PF00069.25 CAR23744.1 - 4.1e-61 206.6 0.0 3.2e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23744.1 - 6.7e-35 120.6 0.0 4.8e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR23744.1 - 0.007 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAR23744.1 - 0.044 13.1 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like PPP5 PF08321.12 CAR23744.1 - 0.11 12.8 0.4 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 PPP5 TPR repeat region Pkinase PF00069.25 CAR23745.1 - 3.5e-72 242.9 0.4 9.1e-72 241.6 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23745.1 - 1.9e-51 174.8 0.0 3.5e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR23745.1 - 0.00011 21.6 0.1 0.002 17.5 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAR23745.1 - 0.02 13.7 0.0 0.044 12.6 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CAR23745.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CAR23745.1 - 0.14 11.8 0.4 0.74 9.4 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CAR23745.1 - 0.46 9.8 3.3 0.59 9.4 0.3 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxysterol_BP PF01237.18 CAR23746.1 - 1.1e-134 449.0 3.4 1.1e-134 449.0 3.4 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 CAR23746.1 - 1.1e-10 41.6 0.1 0.00027 21.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 CAR23746.1 - 1.1e-09 38.8 0.7 3.5e-09 37.1 0.1 2.2 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 CAR23746.1 - 1.7e-09 38.0 0.0 1.1e-05 25.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR23746.1 - 1.8e-09 38.0 0.0 4.8e-05 23.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) PH_8 PF15409.6 CAR23746.1 - 4.7e-08 33.2 0.1 1.3e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.6 CAR23746.1 - 3.5e-07 30.0 0.0 0.064 13.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CAR23746.1 - 4.2e-06 27.0 0.0 0.001 19.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat PH_11 PF15413.6 CAR23746.1 - 0.0032 17.9 1.8 0.026 14.9 0.4 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain HMG_CoA_synt_C PF08540.10 CAR23747.1 - 7.4e-111 370.3 4.1 9.5e-111 369.9 4.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CAR23747.1 - 8.7e-98 325.3 0.2 1.4e-97 324.6 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RPM2 PF08579.11 CAR23748.1 - 9.2e-48 161.6 3.6 2.3e-47 160.3 0.2 3.2 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.6 CAR23748.1 - 2.8e-05 24.2 1.3 3 8.1 0.0 5.8 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 CAR23748.1 - 0.027 14.7 0.0 0.97 9.8 0.0 3.7 3 0 0 3 3 3 0 PPR repeat Ribosomal_L2 PF00181.23 CAR23748.1 - 0.12 12.4 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain Peptidase_M4 PF01447.18 CAR23749.1 - 0.13 12.8 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain Ish1 PF10281.9 CAR23750.1 - 8.7e-44 147.5 50.7 5e-09 36.3 0.0 8.7 9 0 0 9 9 9 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 CAR23750.1 - 0.00011 21.9 0.4 1.2 8.9 0.0 4.6 5 0 0 5 5 5 1 SAP domain HeH PF12949.7 CAR23750.1 - 0.00038 20.1 1.8 0.98 9.2 0.1 3.6 3 0 0 3 3 3 1 HeH/LEM domain SAP30_Sin3_bdg PF13867.6 CAR23750.1 - 0.0039 17.5 0.4 0.67 10.3 0.0 3.8 4 0 0 4 4 4 1 Sin3 binding region of histone deacetylase complex subunit SAP30 YtxH PF12732.7 CAR23750.1 - 0.0074 16.8 72.9 0.86 10.2 12.2 9.5 3 2 3 6 6 6 1 YtxH-like protein DUF883 PF05957.13 CAR23750.1 - 0.43 11.2 54.2 1 10.0 6.1 8.1 5 1 4 9 9 9 0 Bacterial protein of unknown function (DUF883) BORCS7 PF16088.5 CAR23750.1 - 0.75 10.1 6.9 4.4 7.6 0.2 4.3 5 0 0 5 5 5 0 BLOC-1-related complex sub-unit 7 Toprim_3 PF13362.6 CAR23750.1 - 1.6 9.2 21.6 0.26 11.7 0.5 4.4 2 1 2 4 4 4 0 Toprim domain LEA_4 PF02987.16 CAR23750.1 - 9 6.5 132.4 1.4 9.1 11.6 9.0 4 1 5 10 10 10 0 Late embryogenesis abundant protein Rtf2 PF04641.12 CAR23751.1 - 2.4e-32 112.4 0.4 2.6e-31 109.0 0.4 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 CAR23751.1 - 0.0032 17.3 0.2 0.0055 16.5 0.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CAR23751.1 - 0.0076 16.1 0.0 4.1 7.3 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 CAR23751.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_2 PF13639.6 CAR23751.1 - 0.054 13.8 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CAR23751.1 - 0.069 13.0 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 CAR23751.1 - 0.071 13.2 0.4 0.14 12.3 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_5 PF14634.6 CAR23751.1 - 0.082 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAR23751.1 - 0.32 10.9 1.6 0.68 9.8 1.6 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 CAR23751.1 - 0.47 9.9 2.8 0.64 9.5 0.7 2.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-CCCH PF00642.24 CAR23752.1 - 1.5e-07 31.1 18.0 0.00015 21.6 1.2 4.0 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 CAR23752.1 - 0.00021 21.0 0.1 0.00049 19.9 0.0 1.6 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CAR23752.1 - 0.0065 16.5 19.7 0.013 15.5 1.0 3.8 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_3 PF15663.5 CAR23752.1 - 0.048 13.9 3.6 4.7 7.5 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 CAR23752.1 - 0.066 13.9 4.5 6.9 7.4 1.6 2.6 2 1 0 2 2 2 0 Torus domain zf-CCCH_4 PF18044.1 CAR23752.1 - 1.5 8.7 17.2 2.4 8.0 1.6 4.2 5 0 0 5 5 5 0 CCCH-type zinc finger Proteasome PF00227.26 CAR23753.1 - 1.1e-60 204.4 0.0 1.4e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR23753.1 - 2.2e-09 36.8 0.7 4.7e-09 35.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Utp14 PF04615.13 CAR23754.1 - 4.7e-204 680.2 80.3 4.7e-204 680.2 80.3 2.1 1 1 1 2 2 2 1 Utp14 protein Prefoldin PF02996.17 CAR23755.1 - 9.6e-27 93.3 3.9 1.2e-26 93.0 3.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 CAR23755.1 - 0.0027 17.9 6.8 0.0055 17.0 6.7 1.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Imm51 PF15595.6 CAR23755.1 - 0.086 12.8 0.6 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 Immunity protein 51 Rad10 PF03834.14 CAR23756.1 - 6.8e-39 132.4 0.5 6.8e-39 132.4 0.5 1.4 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Asn_synthase PF00733.21 CAR23757.1 - 7.5e-20 71.9 0.2 3.1e-11 43.5 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 CAR23757.1 - 4.5e-10 39.5 0.1 5e-08 32.9 0.1 2.9 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CAR23757.1 - 5.2e-06 26.7 0.0 4.7e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CAR23757.1 - 0.0023 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein Csm4_C PF17953.1 CAR23757.1 - 0.074 12.9 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 CRISPR Csm4 C-terminal domain DUF1319 PF07028.11 CAR23757.1 - 0.09 13.0 1.5 0.16 12.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) VPS9 PF02204.18 CAR23758.1 - 9.2e-26 90.1 0.0 1.6e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CAR23758.1 - 2.2e-10 40.7 0.1 6e-10 39.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 CAR23758.1 - 7e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Dna2 PF08696.11 CAR23758.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 ERO1 PF04137.15 CAR23759.1 - 9.6e-123 409.8 0.9 9.6e-123 409.8 0.9 1.4 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) TFIID-18kDa PF02269.16 CAR23760.1 - 1.3e-29 102.1 0.1 2e-29 101.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 CAR23760.1 - 0.018 15.4 3.8 0.042 14.2 0.0 2.5 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Fungal_trans_2 PF11951.8 CAR23761.1 - 5.4e-104 348.1 0.1 7.3e-104 347.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR23761.1 - 1.3e-12 47.7 6.5 2.8e-12 46.5 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M85 PF13678.6 CAR23761.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 NFkB-p65-degrading zinc protease GFO_IDH_MocA PF01408.22 CAR23762.1 - 3e-23 82.9 0.2 5.7e-23 82.0 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CAR23762.1 - 2.7e-08 33.8 0.0 4.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Shikimate_DH PF01488.20 CAR23762.1 - 0.022 14.8 0.0 0.054 13.6 0.0 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_6 PF00970.24 CAR23763.1 - 3.3e-08 33.8 0.0 5.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.22 CAR23763.1 - 6.8e-08 33.0 0.0 2.5e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.21 CAR23763.1 - 9.5e-06 26.2 0.0 2.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 CAR23763.1 - 0.0097 15.8 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Protoglobin Phage_holin_5_2 PF16079.5 CAR23763.1 - 0.11 12.8 0.0 23 5.4 0.0 2.5 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V NAD_binding_6 PF08030.12 CAR23763.1 - 0.13 12.3 0.2 0.34 11.0 0.2 1.8 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Cys_Met_Meta_PP PF01053.20 CAR23764.1 - 3e-63 213.7 0.0 1.2e-62 211.6 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAR23764.1 - 0.0018 17.3 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V gag_pre-integrs PF13976.6 CAR23764.1 - 0.011 15.5 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 GAG-pre-integrase domain SelA PF03841.13 CAR23764.1 - 0.013 14.5 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase TINF2_N PF14973.6 CAR23764.1 - 0.15 12.4 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus MFS_1 PF07690.16 CAR23765.1 - 6.8e-27 94.3 19.8 6.8e-27 94.3 19.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CAR23765.1 - 1.1e-06 28.3 0.9 1.1e-06 28.3 0.9 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sulfatase PF00884.23 CAR23766.1 - 1.2e-66 225.2 0.0 1.6e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 CAR23766.1 - 0.00017 20.3 0.0 0.00022 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CAR23766.1 - 0.044 13.4 0.6 0.18 11.4 0.4 2.1 2 1 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase FIT1_2 PF17357.2 CAR23767.1 - 4.6e-34 116.4 32.1 4.6e-34 116.4 32.1 2.0 2 0 0 2 2 2 1 Facilitor Of iron transport 1 and 2 Lin-8 PF03353.15 CAR23767.1 - 0.2 11.2 5.6 0.23 11.0 5.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SR-25 PF10500.9 CAR23767.1 - 0.23 11.0 23.5 0.38 10.3 23.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 CAR23767.1 - 0.86 7.6 20.6 0.9 7.5 20.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GREB1 PF15782.5 CAR23767.1 - 3.4 4.7 12.5 3.6 4.6 12.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Miga PF10265.9 CAR23767.1 - 6.3 5.6 8.7 7.2 5.5 8.7 1.2 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 CAR23767.1 - 6.6 5.2 14.4 7.6 4.9 14.4 1.1 1 0 0 1 1 1 0 Macoilin family FIT1_2 PF17357.2 CAR23768.1 - 0.0089 16.1 55.7 0.063 13.4 13.1 3.1 1 1 2 3 3 3 3 Facilitor Of iron transport 1 and 2 DUF756 PF05506.12 CAR23768.1 - 0.047 14.6 0.2 3.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF756) DUF4384 PF14326.6 CAR23768.1 - 0.047 13.8 0.1 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) GLEYA PF10528.9 CAR23768.1 - 9.5 6.7 14.0 11 6.5 3.6 3.0 1 1 1 2 2 2 0 GLEYA domain Ferric_reduct PF01794.19 CAR23769.1 - 3.2e-23 82.2 10.0 3.2e-23 82.2 10.0 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CAR23769.1 - 1.1e-21 77.0 0.9 2.8e-21 75.6 0.0 2.1 3 0 0 3 3 3 1 FAD-binding domain NAD_binding_6 PF08030.12 CAR23769.1 - 3.8e-14 53.1 0.0 8.1e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CAR23769.1 - 0.087 13.5 0.0 1.1 10.0 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain mIF3 PF14877.6 CAR23769.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor MFS_1 PF07690.16 CAR23770.1 - 5.2e-45 153.9 32.0 3.3e-43 148.0 34.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR23770.1 - 5.9e-17 61.7 11.4 5.9e-17 61.7 11.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CAR23770.1 - 5.8e-11 41.5 10.1 5.8e-11 41.5 10.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DoxX_3 PF13781.6 CAR23770.1 - 0.099 13.3 2.5 2 9.1 0.1 3.2 2 0 0 2 2 2 0 DoxX-like family NPIP PF06409.11 CAR23770.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Spy1 PF11357.8 CAR23771.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Cell cycle regulatory protein SLAC1 PF03595.17 CAR23772.1 - 5.1e-68 229.7 26.9 5.9e-68 229.5 26.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4491 PF14898.6 CAR23772.1 - 0.079 13.4 0.0 0.079 13.4 0.0 4.9 6 1 1 7 7 7 0 Domain of unknown function (DUF4491) GST_N PF02798.20 CAR23773.1 - 1.1e-19 70.5 0.1 1.9e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CAR23773.1 - 1.3e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAR23773.1 - 7.2e-08 32.7 0.0 1.4e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAR23773.1 - 4.8e-06 26.8 0.0 9.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR23773.1 - 2.1e-05 24.6 0.0 6.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR23773.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 CAR23774.1 - 8.7e-33 113.7 53.5 9.1e-25 87.3 38.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CAR23774.1 - 4.2e-07 29.2 13.7 7.1e-06 25.1 0.2 2.3 2 0 0 2 2 2 2 MFS_1 like family NADH-u_ox-rdase PF10785.9 CAR23774.1 - 1.7 9.3 4.2 3.1 8.5 0.2 2.9 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Aldo_ket_red PF00248.21 CAR23775.1 - 2.3e-73 247.0 0.1 2.6e-73 246.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_1 PF01979.20 CAR23776.1 - 5e-41 141.1 0.1 6e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR23776.1 - 5.3e-16 59.1 0.0 3.7e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Sugar_tr PF00083.24 CAR23777.1 - 6.7e-92 308.7 20.0 7.9e-92 308.5 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR23777.1 - 5.3e-10 38.8 27.1 1e-09 37.8 25.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CAR23777.1 - 0.00021 20.3 2.3 0.037 12.9 0.7 2.2 2 0 0 2 2 2 2 MFS_1 like family DUF5337 PF17272.2 CAR23777.1 - 4.6 7.1 6.5 3.3 7.6 0.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5337) Alpha-amylase PF00128.24 CAR23778.1 - 1.8e-122 409.1 0.0 3.5e-122 408.2 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CAR23778.1 - 0.0006 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 CAR23778.1 - 0.0049 16.0 0.0 0.0082 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain ABC2_membrane PF01061.24 CAR23779.1 - 1.3e-41 142.3 20.5 1.3e-41 142.3 20.5 1.6 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 CAR23779.1 - 0.0056 16.6 0.1 0.0056 16.6 0.1 2.8 3 0 0 3 3 3 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 CAR23779.1 - 0.84 8.7 19.6 3 6.8 20.0 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Methyltransf_25 PF13649.6 CAR23780.1 - 1.1e-12 48.5 0.0 2.6e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR23780.1 - 1.7e-12 47.8 0.0 4.6e-12 46.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR23780.1 - 1.4e-08 35.4 0.0 2.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR23780.1 - 2.6e-08 33.8 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR23780.1 - 3.4e-07 30.2 0.0 5.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR23780.1 - 0.00029 20.3 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CAR23780.1 - 0.017 14.6 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Rap1a PF18602.1 CAR23780.1 - 0.039 14.3 0.0 0.074 13.4 0.0 1.4 1 0 0 1 1 1 0 Rap1a immunity proteins Pectate_lyase PF03211.13 CAR23781.1 - 6.1e-77 257.8 4.8 7.1e-77 257.5 4.8 1.0 1 0 0 1 1 1 1 Pectate lyase Vel1p PF10339.9 CAR23782.1 - 8e-109 361.6 2.4 9e-109 361.4 2.4 1.0 1 0 0 1 1 1 1 Yeast-specific zinc responsive Homeodomain PF00046.29 CAR23783.1 - 9.1e-07 28.6 0.2 1.8e-06 27.7 0.1 1.5 2 0 0 2 2 2 1 Homeodomain Cons_hypoth698 PF03601.14 CAR23783.1 - 0.19 10.5 0.1 0.27 10.1 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 HofP PF10748.9 CAR23784.1 - 0.015 14.8 0.0 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 DNA utilization proteins HofP DHO_dh PF01180.21 CAR23785.1 - 6.7e-92 307.8 0.0 7.6e-92 307.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CAR23785.1 - 3.7e-06 26.2 0.0 0.00032 19.8 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Mito_carr PF00153.27 CAR23786.1 - 2e-58 194.3 2.3 2.2e-19 69.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Staph_haemo PF05480.11 CAR23787.1 - 0.041 13.7 0.6 0.061 13.1 0.6 1.3 1 0 0 1 1 1 0 Staphylococcus haemolytic protein MATalpha_HMGbox PF04769.12 CAR23788.1 - 4.7e-14 52.2 1.8 6.5e-14 51.7 1.8 1.3 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Sfi1 PF08457.10 CAR23788.1 - 0.018 13.6 1.0 0.025 13.1 1.0 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein DUF3130 PF11328.8 CAR23788.1 - 0.071 13.4 0.3 0.15 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 DUF5617 PF18493.1 CAR23788.1 - 1.3 9.1 5.5 0.22 11.6 0.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5617) Homeobox_KN PF05920.11 CAR23789.1 - 2.8e-11 43.1 1.1 4.4e-11 42.5 1.1 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CAR23789.1 - 1.3e-08 34.6 4.0 1.9e-08 34.0 4.0 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CAR23789.1 - 0.02 14.4 0.1 0.043 13.3 0.1 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez PALP PF00291.25 CAR23790.1 - 1.3e-59 202.0 0.0 1.5e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Vac17 PF17321.2 CAR23791.1 - 2.8e-115 386.3 16.1 3.2e-115 386.1 16.1 1.0 1 0 0 1 1 1 1 Vacuole-related protein 17 MRC1 PF09444.10 CAR23792.1 - 4.6e-38 131.0 12.1 4.6e-38 131.0 12.1 4.8 5 1 1 6 6 6 1 MRC1-like domain KH_8 PF17903.1 CAR23793.1 - 1e-31 108.8 0.0 2.2e-31 107.8 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CAR23793.1 - 0.032 14.1 0.0 0.082 12.8 0.0 1.8 1 1 0 1 1 1 0 KH domain DUF883 PF05957.13 CAR23793.1 - 0.72 10.5 3.1 1.5 9.5 3.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF543 PF04418.12 CAR23795.1 - 3.6e-31 107.0 0.3 3.9e-31 106.9 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) PEX11 PF05648.14 CAR23796.1 - 0.00055 19.5 0.2 0.00081 18.9 0.2 1.3 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) 2OG-FeII_Oxy_2 PF13532.6 CAR23797.1 - 9.6e-21 74.9 0.0 1.4e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_ribbon_recom PF13408.6 CAR23797.1 - 0.099 13.2 0.5 0.31 11.6 0.5 1.9 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain THDPS_N_2 PF14805.6 CAR23798.1 - 0.012 15.8 0.0 7.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Voltage_CLC PF00654.20 CAR23799.1 - 1.3e-77 261.4 22.7 2.1e-77 260.8 22.7 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel Phage_holin_3_1 PF05106.12 CAR23799.1 - 0.66 10.5 0.0 0.66 10.5 0.0 2.6 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) MT-A70 PF05063.14 CAR23800.1 - 1.3e-12 48.0 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 MT-A70 CMAS PF02353.20 CAR23801.1 - 3.1e-61 207.1 0.5 3.8e-61 206.8 0.5 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CAR23801.1 - 1.7e-10 41.0 0.0 2.8e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR23801.1 - 5.2e-10 39.8 0.0 1e-09 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR23801.1 - 1.4e-09 38.5 0.0 2.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR23801.1 - 1.2e-06 29.2 0.0 2.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR23801.1 - 1.2e-05 25.1 0.1 3.1e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 CAR23801.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 COX7C PF02935.16 CAR23801.1 - 0.012 15.9 4.1 0.012 15.9 4.1 1.7 2 0 0 2 2 1 0 Cytochrome c oxidase subunit VIIc MTS PF05175.14 CAR23801.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 CAR23801.1 - 0.029 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CAR23801.1 - 0.049 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spb1_C PF07780.12 CAR23802.1 - 7.2e-84 280.7 22.0 7.2e-84 280.7 22.0 3.7 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 CAR23802.1 - 1.7e-54 184.6 0.0 3.3e-54 183.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CAR23802.1 - 6.7e-45 152.8 14.6 6.7e-45 152.8 14.6 5.3 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) PIG-X PF08320.12 CAR23803.1 - 8.9e-29 100.9 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 UCR_14kD PF02271.16 CAR23805.1 - 4.8e-39 132.4 0.1 5.6e-39 132.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit She9_MDM33 PF05546.11 CAR23805.1 - 0.059 13.2 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family ATP_transf PF09830.9 CAR23806.1 - 1.9e-21 76.0 0.0 3e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CAR23806.1 - 0.00031 20.1 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 CAR23806.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 CAR23806.1 - 0.046 14.5 0.0 0.12 13.2 0.0 1.6 1 0 0 1 1 1 0 HIT domain Fumble PF03630.14 CAR23807.1 - 3.2e-128 427.5 1.2 3.8e-127 424.0 1.2 1.9 1 1 0 1 1 1 1 Fumble Kre28 PF17097.5 CAR23808.1 - 5.3e-132 440.2 16.4 5.9e-132 440.1 16.4 1.0 1 0 0 1 1 1 1 Spindle pole body component DUF3509 PF12021.8 CAR23808.1 - 0.07 12.9 2.5 0.13 12.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) DUF5101 PF17031.5 CAR23808.1 - 0.15 12.2 3.7 3.2 7.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) Synaptobrevin PF00957.21 CAR23808.1 - 0.28 11.0 3.7 0.21 11.4 0.9 2.3 2 0 0 2 2 2 0 Synaptobrevin bZIP_1 PF00170.21 CAR23808.1 - 2.6 8.2 9.7 4.1 7.6 0.1 4.2 3 1 1 4 4 4 0 bZIP transcription factor YtxH PF12732.7 CAR23808.1 - 2.8 8.5 5.3 13 6.4 0.2 3.5 3 1 0 3 3 3 0 YtxH-like protein Atg14 PF10186.9 CAR23808.1 - 5 6.1 16.8 0.19 10.8 10.7 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 CAR23808.1 - 6.8 7.4 21.5 3.3 8.4 1.3 4.5 2 1 2 4 4 4 0 Initiation control protein YabA RPAP1_C PF08620.10 CAR23809.1 - 5.2e-29 100.2 0.1 1.1e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CAR23809.1 - 2.5e-17 62.4 3.3 4.9e-17 61.4 3.3 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.22 CAR23809.1 - 0.12 12.7 0.3 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 HEAT repeat Pmp3 PF01679.17 CAR23810.1 - 1.4e-18 66.8 4.0 1.7e-18 66.6 4.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Asp_Glu_race PF01177.22 CAR23811.1 - 0.0096 15.8 0.2 0.029 14.2 0.2 1.8 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase ArfGap PF01412.18 CAR23812.1 - 1.5e-33 115.3 1.3 4.1e-33 113.9 1.3 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 CAR23812.1 - 1.7e-09 38.1 1.0 3.8e-09 37.0 0.3 2.1 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 CAR23812.1 - 7.1e-05 22.6 0.1 0.00015 21.6 0.1 1.4 1 0 0 1 1 1 1 BAR domain of APPL family Pkinase PF00069.25 CAR23813.1 - 3.7e-67 226.5 0.0 5.2e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23813.1 - 1.8e-46 158.5 0.0 2.7e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR23813.1 - 2.3e-05 23.9 0.0 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CAR23813.1 - 5.9e-05 22.0 0.2 0.0077 15.0 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 CAR23813.1 - 0.015 14.3 0.2 0.35 9.8 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain ABC1 PF03109.16 CAR23813.1 - 0.015 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Recep_L_domain PF01030.24 CAR23814.1 - 2e-06 27.9 0.9 0.0027 17.8 0.1 4.1 1 1 1 4 4 4 3 Receptor L domain LRR_4 PF12799.7 CAR23814.1 - 0.019 15.4 6.3 15 6.1 0.7 4.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) YccF PF03733.13 CAR23814.1 - 0.66 10.7 3.7 1.2 9.9 3.7 1.5 1 0 0 1 1 1 0 Inner membrane component domain Zn_clus PF00172.18 CAR23815.1 - 0.0015 18.7 7.0 0.0029 17.7 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApoA-II PF04711.13 CAR23815.1 - 0.15 12.2 0.1 0.55 10.4 0.1 2.0 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) CTP_transf_like PF01467.26 CAR23816.1 - 8e-08 32.6 0.0 1.4e-07 31.8 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 CAR23816.1 - 0.066 12.4 0.0 7.3 5.7 0.0 2.2 2 0 0 2 2 2 0 HIGH Nucleotidyl Transferase ATP-sulfurylase PF01747.17 CAR23816.1 - 0.11 12.0 0.0 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 ATP-sulfurylase FKBP_C PF00254.28 CAR23817.1 - 9.4e-31 106.0 0.0 1.1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EMC1_C PF07774.13 CAR23818.1 - 3.2e-65 219.8 0.2 9.4e-65 218.3 0.0 1.9 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CAR23818.1 - 0.00017 21.3 0.0 0.0033 17.0 0.0 2.6 2 1 0 2 2 2 1 PQQ-like domain WD40_like PF17005.5 CAR23818.1 - 0.041 13.2 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PQQ PF01011.21 CAR23818.1 - 0.051 13.5 0.1 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat COX5A PF02284.16 CAR23818.1 - 0.18 11.8 0.3 0.5 10.4 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va Mgr1 PF08602.10 CAR23819.1 - 1.1e-159 531.4 0.0 1.3e-159 531.2 0.0 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.20 CAR23820.1 - 2e-57 191.6 0.0 8.1e-30 102.9 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CAR23820.1 - 2.3e-27 96.1 2.3 6.5e-21 75.1 1.6 4.2 4 1 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAR23820.1 - 2.5e-10 40.4 0.3 0.00074 19.7 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 CAR23820.1 - 2.2e-06 27.2 0.0 0.0012 18.2 0.0 3.1 3 1 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CAR23820.1 - 7.7e-06 26.3 0.8 0.29 11.6 0.1 3.3 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CAR23820.1 - 9e-06 25.6 0.1 0.012 15.5 0.0 3.5 2 1 1 3 3 3 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CAR23820.1 - 0.00011 22.5 0.0 0.29 11.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.17 CAR23820.1 - 0.00041 19.5 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 Calsequestrin Redoxin PF08534.10 CAR23820.1 - 0.0029 17.3 0.4 1.7 8.4 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.6 CAR23820.1 - 0.23 11.6 2.2 4.9 7.3 0.2 3.3 2 2 0 3 3 3 0 Thioredoxin GRASP55_65 PF04495.14 CAR23821.1 - 5.8e-36 123.8 0.0 1.5e-33 116.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CAR23821.1 - 0.2 11.5 1.2 1.3 8.9 0.2 2.5 2 1 0 2 2 2 0 PDZ domain Hexokinase_2 PF03727.16 CAR23822.1 - 3.1e-76 256.0 0.0 4.4e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CAR23822.1 - 2.7e-69 233.1 0.0 4.1e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.32 CAR23823.1 - 1.7e-16 60.3 0.8 0.011 16.5 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR23823.1 - 1.6e-07 31.5 0.0 0.037 14.3 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CAR23823.1 - 0.023 14.6 0.2 0.07 13.1 0.2 1.9 1 0 0 1 1 1 0 LisH Lactonase PF10282.9 CAR23823.1 - 0.039 13.2 0.0 0.99 8.6 0.0 2.3 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller ATG22 PF11700.8 CAR23824.1 - 7.4e-154 512.9 23.1 8.7e-154 512.7 23.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like La PF05383.17 CAR23825.1 - 2.4e-17 62.7 0.0 6.4e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 La domain DUF573 PF04504.14 CAR23826.1 - 0.029 15.0 1.6 0.077 13.7 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF573 FMP23 PF17315.2 CAR23826.1 - 0.12 12.6 0.7 0.21 11.7 0.7 1.4 1 0 0 1 1 1 0 Found in mitochondrial proteome SF3a60_bindingd PF12108.8 CAR23826.1 - 0.27 11.2 1.1 0.72 9.8 1.1 1.8 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Flocculin_t3 PF13928.6 CAR23827.1 - 4.3e-14 52.8 150.5 9.3e-06 26.1 10.0 11.2 7 3 2 9 9 9 6 Flocculin type 3 repeat Glutaredoxin PF00462.24 CAR23828.1 - 6.2e-13 48.8 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.6 CAR23828.1 - 0.03 14.5 0.0 0.046 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CAR23828.1 - 0.12 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin GAT PF03127.14 CAR23829.1 - 0.00019 21.6 0.9 0.00038 20.7 0.1 2.0 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 CAR23829.1 - 0.0057 16.5 0.1 0.011 15.6 0.1 1.7 1 1 0 1 1 1 1 VHS domain SelR PF01641.18 CAR23830.1 - 9.3e-49 164.5 0.6 1.1e-48 164.3 0.6 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 CAR23830.1 - 0.0073 16.5 0.4 0.014 15.6 0.4 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.9 CAR23830.1 - 0.083 11.7 0.3 3.9 6.2 0.1 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Lar_restr_allev PF14354.6 CAR23830.1 - 0.74 10.2 6.1 3.5 8.1 1.3 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 CAR23830.1 - 2.6 7.6 12.7 1.9 8.0 0.8 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-Mss51 PF13824.6 CAR23830.1 - 3.4 7.9 6.7 1.2 9.3 0.4 2.8 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3128 PF11326.8 CAR23831.1 - 8.5e-27 93.3 1.9 9.6e-27 93.2 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) IBV_3B PF03622.13 CAR23831.1 - 0.11 12.7 0.7 0.51 10.5 0.5 2.2 1 1 1 2 2 2 0 IBV 3B protein RA PF00788.23 CAR23832.1 - 1.2e-15 57.8 0.2 3.6e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain SAM_Ste50p PF09235.10 CAR23832.1 - 2.1e-14 53.5 1.3 4e-14 52.6 1.3 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Ecl1 PF12855.7 CAR23832.1 - 0.47 11.6 4.7 0.65 11.1 4.7 1.2 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins RRM_Rrp7 PF17799.1 CAR23833.1 - 7.1e-44 149.5 0.8 7.1e-44 149.5 0.8 1.9 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 CAR23833.1 - 3.7e-26 91.6 11.0 3.7e-26 91.6 11.0 2.0 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 CAR23833.1 - 0.0062 16.8 0.1 0.0062 16.8 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF5093) Adenyl_cycl_N PF12633.7 CAR23833.1 - 0.032 14.1 0.4 0.032 14.1 0.4 2.1 3 0 0 3 3 3 0 Adenylate cyclase NT domain PRCC PF10253.9 CAR23833.1 - 0.16 12.8 5.7 0.23 12.2 5.7 1.6 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Complex1_LYR_2 PF13233.6 CAR23834.1 - 1.9e-18 67.0 0.0 2.6e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CAR23834.1 - 1e-11 44.7 0.0 2.1e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histidinol_dh PF00815.20 CAR23835.1 - 1.1e-160 535.1 1.0 1.9e-160 534.4 1.0 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CAR23835.1 - 2.6e-26 91.3 0.2 5.9e-26 90.1 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CAR23835.1 - 2.4e-17 63.1 0.4 8.2e-17 61.4 0.4 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase CAP_GLY PF01302.25 CAR23836.1 - 6.8e-15 54.8 0.5 6.8e-15 54.8 0.5 1.8 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CAR23836.1 - 0.00021 21.0 0.9 0.00033 20.4 0.9 1.3 1 0 0 1 1 1 1 CLIP1 zinc knuckle Lebercilin PF15619.6 CAR23836.1 - 0.0004 20.1 41.8 0.023 14.4 17.4 2.8 1 1 1 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease ABC_tran_CTD PF16326.5 CAR23836.1 - 0.0033 17.6 7.4 0.0033 17.6 7.4 4.1 2 1 2 4 4 4 1 ABC transporter C-terminal domain PspA_IM30 PF04012.12 CAR23836.1 - 0.011 15.4 25.3 0.011 15.4 25.3 2.7 1 1 2 3 3 3 0 PspA/IM30 family CorA PF01544.18 CAR23836.1 - 0.02 14.2 18.4 0.23 10.7 9.2 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CCDC-167 PF15188.6 CAR23836.1 - 0.026 14.8 7.4 0.026 14.8 7.4 3.9 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 167 TMPIT PF07851.13 CAR23836.1 - 0.068 12.4 21.7 0.069 12.4 7.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein ApoA-II PF04711.13 CAR23836.1 - 0.087 13.0 0.4 0.087 13.0 0.4 2.7 1 1 1 2 2 2 0 Apolipoprotein A-II (ApoA-II) CALCOCO1 PF07888.11 CAR23836.1 - 0.33 9.8 36.8 0.5 9.2 36.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Seryl_tRNA_N PF02403.22 CAR23836.1 - 0.39 11.0 31.5 0.75 10.0 2.7 3.9 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.6 CAR23836.1 - 1.1 7.9 29.1 0.73 8.4 25.1 1.9 1 1 1 2 2 2 0 AAA domain Fez1 PF06818.15 CAR23836.1 - 1.1 9.7 36.3 1.6 9.1 10.7 2.2 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 CAR23836.1 - 1.2 8.0 41.4 3 6.6 10.9 2.6 1 1 0 2 2 2 0 Spc7 kinetochore protein HAUS6_N PF14661.6 CAR23836.1 - 1.4 8.4 28.4 1.7 8.2 8.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus zf-C4H2 PF10146.9 CAR23836.1 - 1.4 9.1 27.5 6.7 7.0 9.8 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein DUF3584 PF12128.8 CAR23836.1 - 2.1 5.7 31.9 3.6 5.0 31.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SlyX PF04102.12 CAR23836.1 - 3.1 8.5 34.2 17 6.1 10.9 4.8 1 1 4 5 5 5 0 SlyX Filament PF00038.21 CAR23836.1 - 3.1 7.3 38.9 1.4 8.4 16.6 2.6 1 1 0 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 CAR23836.1 - 3.4 7.8 30.1 0.58 10.3 10.4 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tho2 PF11262.8 CAR23836.1 - 3.9 6.6 21.9 2.5 7.2 6.1 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 CAR23836.1 - 5.2 6.3 28.3 16 4.7 13.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CAR23836.1 - 5.5 7.0 19.3 1.2 9.2 3.8 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) CSN5_C PF18323.1 CAR23836.1 - 5.9 7.9 20.2 4.1 8.4 1.1 4.1 3 3 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Phage_Nu1 PF07471.12 CAR23836.1 - 6.1 6.6 18.0 1.1 9.0 1.2 3.5 2 2 2 4 4 4 0 Phage DNA packaging protein Nu1 ADIP PF11559.8 CAR23836.1 - 6.5 6.8 38.0 11 6.1 13.8 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 CAR23836.1 - 6.6 6.2 40.0 0.59 9.7 15.7 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 CAR23836.1 - 7 6.7 42.8 0.94 9.5 17.9 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 CAR23836.1 - 7.8 6.9 46.0 0.4 11.0 12.7 3.2 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Laminin_II PF06009.12 CAR23836.1 - 8.6 6.4 23.8 4.5 7.3 6.9 2.9 1 1 2 3 3 3 0 Laminin Domain II Tropomyosin_1 PF12718.7 CAR23836.1 - 9.3 6.4 45.0 0.5 10.5 18.2 2.7 1 1 1 2 2 2 0 Tropomyosin like TPR_2 PF07719.17 CAR23838.1 - 0.002 18.1 0.0 0.0078 16.3 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR23838.1 - 0.003 17.3 0.0 0.013 15.3 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat RNA_pol_Rpb1_6 PF04992.14 CAR23838.1 - 0.0081 16.0 0.3 0.012 15.5 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 TPR_16 PF13432.6 CAR23838.1 - 0.024 15.3 0.0 0.061 14.0 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 CAR23838.1 - 0.044 14.1 0.2 0.08 13.3 0.2 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat EzrA PF06160.12 CAR23838.1 - 0.074 11.2 0.5 0.1 10.8 0.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_14 PF13428.6 CAR23838.1 - 0.25 12.3 0.0 0.59 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP PF00188.26 CAR23839.1 - 8.6e-19 68.6 2.1 3.5e-18 66.7 2.1 2.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SH3_9 PF14604.6 CAR23840.1 - 0.00025 20.9 0.0 0.00055 19.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.6 CAR23840.1 - 0.001 18.9 0.1 0.019 14.8 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4448) SH3_1 PF00018.28 CAR23840.1 - 0.005 16.4 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAR23840.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Stevor PF17410.2 CAR23840.1 - 0.13 11.7 0.8 0.25 10.9 0.8 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Nitroreductase PF00881.24 CAR23841.1 - 2.1e-06 27.9 0.0 3.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family AA_permease PF00324.21 CAR23842.1 - 4.1e-134 447.8 32.5 5.1e-134 447.5 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23842.1 - 3.1e-33 115.3 34.8 3.7e-33 115.0 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease Aim19 PF10315.9 CAR23842.1 - 0.61 10.4 4.2 0.22 11.8 1.1 1.9 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 19 AA_permease PF00324.21 CAR23843.1 - 1.7e-130 435.9 34.7 2e-130 435.6 34.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23843.1 - 3.9e-35 121.5 34.6 4.9e-35 121.2 34.6 1.0 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 CAR23843.1 - 0.00058 19.3 8.1 0.0016 17.8 8.1 1.7 1 0 0 1 1 1 1 Sodium:alanine symporter family Rad60-SLD PF11976.8 CAR23845.1 - 8.1e-20 70.4 0.1 1e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CAR23845.1 - 1.2e-13 50.6 0.0 1.4e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 CAR23846.1 - 3.7e-71 239.6 0.0 7.4e-71 238.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23846.1 - 4.8e-35 121.1 0.0 1.1e-34 119.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 CAR23846.1 - 4e-33 113.6 2.0 1.1e-32 112.2 2.0 1.8 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 CAR23846.1 - 8.5e-07 28.6 0.0 8.6e-06 25.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAR23846.1 - 8.2 6.3 6.6 0.53 10.2 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cu-oxidase_2 PF07731.14 CAR23847.1 - 5.7e-33 113.6 5.2 1.7e-30 105.5 0.6 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAR23847.1 - 5.4e-21 74.8 10.7 6.2e-19 68.2 2.7 5.1 3 3 2 5 5 5 1 Multicopper oxidase Cu-oxidase PF00394.22 CAR23847.1 - 2.6e-20 73.1 0.1 2.1e-18 66.9 0.0 3.0 3 1 0 3 3 3 1 Multicopper oxidase PSP1 PF04468.12 CAR23848.1 - 8.2e-42 141.4 3.2 8.2e-42 141.4 3.2 2.1 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Sporozoite_P67 PF05642.11 CAR23848.1 - 0.00039 18.7 4.1 0.00067 17.9 4.1 1.3 1 0 0 1 1 1 1 Sporozoite P67 surface antigen TFIIA PF03153.13 CAR23848.1 - 0.1 12.5 14.0 0.19 11.7 14.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIF4E-T PF10477.9 CAR23848.1 - 0.89 8.3 9.3 1.6 7.5 9.3 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E PBP PF01161.20 CAR23849.1 - 1.5e-21 77.1 0.1 2.1e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PAP2 PF01569.21 CAR23850.1 - 5.2e-24 84.6 1.2 5.2e-24 84.6 1.2 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CAR23850.1 - 0.00035 20.3 3.2 0.00035 20.3 3.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CAR23850.1 - 0.0039 17.7 2.5 0.011 16.2 2.5 1.7 1 0 0 1 1 1 1 PAP2 superfamily C-terminal FUSC_2 PF13515.6 CAR23850.1 - 1.5 9.0 7.3 0.11 12.6 1.9 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein-like S-AdoMet_synt_C PF02773.16 CAR23851.1 - 3e-64 215.1 0.0 5.8e-64 214.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CAR23851.1 - 2.9e-46 156.6 0.0 7.4e-46 155.3 0.0 1.7 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CAR23851.1 - 1.3e-45 154.1 0.1 2.8e-45 153.0 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 CAR23851.1 - 0.036 12.9 0.1 0.12 11.1 0.0 1.8 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Vta1 PF04652.16 CAR23852.1 - 2.5e-32 111.8 0.5 2.5e-32 111.8 0.5 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 CAR23852.1 - 2.8e-15 55.7 1.8 2.8e-15 55.7 1.8 2.3 2 0 0 2 2 2 1 Vta1 C-terminal domain B PF02216.16 CAR23852.1 - 0.046 13.7 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 B domain Swi6_N PF18530.1 CAR23853.1 - 4.8e-28 97.4 0.1 1.6e-27 95.8 0.1 1.9 1 0 0 1 1 1 1 Swi6 N-terminal domain Ank_5 PF13857.6 CAR23853.1 - 8.6e-09 35.5 0.7 6.5e-06 26.3 0.1 2.9 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CAR23853.1 - 1e-08 35.2 4.7 0.0011 19.3 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CAR23853.1 - 1.4e-08 34.3 0.4 0.00079 19.7 0.0 4.0 4 0 0 4 4 3 2 Ankyrin repeat Ank_2 PF12796.7 CAR23853.1 - 1.4e-08 35.2 0.1 0.001 19.6 0.0 2.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR23853.1 - 2e-08 34.6 0.8 0.0058 17.2 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) ATG16 PF08614.11 CAR23853.1 - 0.00034 20.9 4.1 0.00034 20.9 4.1 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 CAR23853.1 - 0.01 15.3 6.2 0.01 15.3 6.2 1.5 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Herpes_U5 PF05999.11 CAR23853.1 - 0.011 14.6 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U5-like family Phage_GPO PF05929.11 CAR23853.1 - 0.015 14.9 3.4 0.035 13.7 3.4 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IMD PF08397.11 CAR23853.1 - 0.063 12.6 2.3 0.16 11.4 2.3 1.6 1 0 0 1 1 1 0 IRSp53/MIM homology domain Phlebovirus_NSM PF07246.11 CAR23853.1 - 0.12 11.8 3.5 0.19 11.0 3.5 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Tho2 PF11262.8 CAR23853.1 - 0.14 11.4 2.7 0.15 11.2 0.9 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Exonuc_VII_L PF02601.15 CAR23853.1 - 0.25 10.8 9.3 0.64 9.5 9.3 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 CAR23853.1 - 0.73 8.9 7.6 0.11 11.6 3.7 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SesA PF17107.5 CAR23853.1 - 0.77 10.0 6.8 14 5.9 2.4 2.5 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_PEP_C PF04513.12 CAR23853.1 - 0.84 9.7 5.7 0.57 10.2 2.5 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.6 CAR23853.1 - 1 8.7 11.6 1.3 8.3 7.6 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HIP1_clath_bdg PF16515.5 CAR23853.1 - 1.3 9.7 10.1 0.43 11.2 5.3 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Cor1 PF04803.12 CAR23853.1 - 1.3 9.2 12.0 0.14 12.4 7.2 1.8 2 0 0 2 2 1 0 Cor1/Xlr/Xmr conserved region FapA PF03961.13 CAR23853.1 - 2.5 6.6 7.3 0.23 10.1 2.6 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 CAR23853.1 - 3.4 8.0 9.7 0.52 10.6 5.3 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FHA PF00498.26 CAR23854.1 - 1.2e-06 28.7 0.0 4.2e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 FHA domain Aldo_ket_red PF00248.21 CAR23855.1 - 1.4e-29 103.3 0.0 1.3e-27 96.7 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L37e PF01907.19 CAR23856.1 - 5.9e-29 100.0 11.1 5.9e-29 100.0 11.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.7 CAR23856.1 - 0.0039 17.2 1.4 0.0055 16.7 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 CAR23856.1 - 0.0074 15.7 2.0 0.012 15.0 2.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.19 CAR23856.1 - 0.16 12.0 1.1 0.21 11.6 1.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 CAR23856.1 - 0.19 11.9 2.0 0.34 11.0 2.0 1.5 1 1 0 1 1 1 0 Zinc ribbon domain DUF1258 PF06869.12 CAR23856.1 - 0.3 10.6 4.9 0.18 11.3 3.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) YhfH PF14149.6 CAR23856.1 - 1.8 8.6 5.4 1.6 8.8 0.6 2.2 1 1 1 2 2 2 0 YhfH-like protein zf-HYPF PF07503.12 CAR23856.1 - 8.1 6.3 8.6 49 3.8 5.6 2.8 2 1 0 2 2 2 0 HypF finger LCD1 PF09798.9 CAR23857.1 - 5.9e-182 606.4 1.7 6.7e-182 606.2 1.7 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein EMG1 PF03587.14 CAR23858.1 - 2.7e-78 262.1 0.0 3.3e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 CAR23858.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein RP854 YbaJ PF10757.9 CAR23859.1 - 0.083 13.4 0.2 0.25 11.9 0.2 1.8 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ APG17 PF04108.12 CAR23859.1 - 0.1 11.7 2.6 0.27 10.3 0.0 2.3 2 0 0 2 2 2 0 Autophagy protein Apg17 RAC_head PF16717.5 CAR23859.1 - 0.11 13.5 0.3 12 6.9 0.0 3.1 3 0 0 3 3 3 0 Ribosome-associated complex head domain Collagen_mid PF15984.5 CAR23859.1 - 0.26 11.0 3.3 4.3 7.0 0.3 2.5 2 0 0 2 2 2 0 Bacterial collagen, middle region DUF948 PF06103.11 CAR23859.1 - 0.43 10.9 13.4 0.31 11.3 0.2 4.4 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Peptidase_M56 PF05569.11 CAR23859.1 - 0.45 9.7 12.7 0.072 12.3 4.2 2.9 3 0 0 3 3 3 0 BlaR1 peptidase M56 PH PF00169.29 CAR23860.1 - 9.9e-08 32.4 1.2 1.3e-06 28.9 0.0 2.6 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 CAR23860.1 - 0.14 12.5 0.2 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain ABC_membrane PF00664.23 CAR23861.1 - 2.4e-62 211.1 2.6 3.2e-62 210.7 2.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CAR23861.1 - 2.2e-30 105.9 0.1 1.8e-29 103.0 0.0 2.6 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 CAR23861.1 - 3.2e-06 26.8 0.0 1.4e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CAR23861.1 - 8.1e-06 26.2 0.2 0.0016 18.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR23861.1 - 0.0025 18.3 0.1 0.32 11.6 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CAR23861.1 - 0.0064 16.5 0.6 0.13 12.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR23861.1 - 0.0066 16.9 0.2 0.037 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CAR23861.1 - 0.0095 15.7 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 CAR23861.1 - 0.011 15.4 0.0 0.036 13.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 CAR23861.1 - 0.047 13.5 0.0 0.23 11.2 0.0 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF87 PF01935.17 CAR23861.1 - 0.054 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 CAR23861.1 - 0.06 13.8 0.2 3.1 8.2 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 CAR23861.1 - 0.069 11.9 0.0 0.14 10.9 0.0 1.5 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 CAR23861.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAR23861.1 - 0.088 13.2 0.2 3.9 7.9 0.0 2.9 2 1 1 3 3 3 0 RNA helicase SbcCD_C PF13558.6 CAR23861.1 - 0.11 12.7 0.8 1.4 9.2 0.8 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 CAR23861.1 - 0.48 10.2 1.7 5.8 6.6 0.1 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Abhydrolase_1 PF00561.20 CAR23862.1 - 3.3e-66 223.6 0.1 4.1e-66 223.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR23862.1 - 8.6e-05 23.2 0.1 0.00014 22.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MPM1 PF17234.2 CAR23862.1 - 0.096 12.9 1.1 0.19 12.0 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 SR-25 PF10500.9 CAR23862.1 - 8 6.0 19.7 12 5.4 19.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_transf_28 PF03033.20 CAR23863.1 - 5.8e-31 107.4 0.0 3.9e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CAR23863.1 - 6.2e-25 87.3 0.9 1.3e-21 76.6 0.0 2.9 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 CAR23863.1 - 3.4e-10 40.3 0.1 1.4e-09 38.4 0.1 2.1 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 CAR23863.1 - 1.6e-09 37.1 0.0 3.4e-09 36.0 0.0 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.6 CAR23863.1 - 9.3e-06 26.0 0.2 3.4e-05 24.2 0.2 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Glyco_trans_4_4 PF13579.6 CAR23863.1 - 0.19 12.1 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Exo_endo_phos PF03372.23 CAR23864.1 - 2.6e-13 50.0 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HP0268 PF18618.1 CAR23864.1 - 0.032 14.6 0.0 0.08 13.4 0.0 1.6 1 0 0 1 1 1 0 HP0268 Spindle_Spc25 PF08234.12 CAR23865.1 - 5e-15 55.5 0.1 1.4e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 DUF4559 PF15112.6 CAR23865.1 - 0.12 12.0 13.9 0.12 12.1 12.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Phage_tail_APC PF16778.5 CAR23865.1 - 0.17 11.7 1.7 0.51 10.2 1.7 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein M PF02370.16 CAR23865.1 - 0.19 12.4 12.2 1.6 9.6 0.1 3.8 3 0 0 3 3 2 0 M protein repeat Spc24 PF08286.11 CAR23865.1 - 0.58 10.4 21.0 0.28 11.4 10.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 zf-C4H2 PF10146.9 CAR23865.1 - 0.65 10.3 13.3 0.72 10.1 13.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Atg14 PF10186.9 CAR23865.1 - 0.84 8.7 25.6 33 3.4 25.6 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Glucan_synthase PF02364.15 CAR23865.1 - 0.95 7.5 5.6 1.1 7.3 5.6 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase component APG6_N PF17675.1 CAR23865.1 - 1.1 9.8 28.1 2.8 8.5 28.0 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Peptidase_S46 PF10459.9 CAR23865.1 - 1.4 7.5 9.1 1.5 7.4 9.1 1.0 1 0 0 1 1 1 0 Peptidase S46 Exonuc_VII_L PF02601.15 CAR23865.1 - 6.5 6.2 12.4 7.9 5.9 12.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Per1 PF04080.13 CAR23866.1 - 2.1e-88 296.4 9.0 2.5e-88 296.2 9.0 1.0 1 0 0 1 1 1 1 Per1-like family DUF5087 PF17006.5 CAR23866.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5087) Ni_hydr_CYTB PF01292.20 CAR23866.1 - 0.3 10.7 7.6 0.029 14.0 2.2 2.0 3 0 0 3 3 3 0 Prokaryotic cytochrome b561 HCO3_cotransp PF00955.21 CAR23867.1 - 2.8e-77 260.7 11.5 4.3e-40 138.0 1.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF4235 PF14019.6 CAR23867.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DUF4190 PF13828.6 CAR23868.1 - 0.098 12.4 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4190) 2-Hacid_dh_C PF02826.19 CAR23869.1 - 3.7e-56 189.3 0.0 8.3e-56 188.2 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR23869.1 - 1.4e-12 47.4 0.0 2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CAR23869.1 - 2.6e-06 27.7 0.3 2e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CAR23869.1 - 9.9e-05 22.0 0.0 0.00026 20.6 0.0 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Peptidase_M1_N PF17900.1 CAR23870.1 - 3.4e-05 24.1 0.1 0.0017 18.6 0.1 2.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CAR23870.1 - 7.6e-05 22.4 0.0 0.00019 21.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 CAR23870.1 - 0.12 12.8 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats Sad1_UNC PF07738.13 CAR23871.1 - 2.6e-29 101.9 2.1 3e-29 101.7 0.1 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal FidL_like PF15941.5 CAR23871.1 - 6.3 7.3 8.6 2.2 8.8 0.6 3.2 3 0 0 3 3 3 0 FidL-like putative membrane protein Cyclin_N PF00134.23 CAR23872.1 - 1.1e-37 128.5 0.3 5.8e-37 126.3 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR23872.1 - 0.46 10.6 8.3 0.058 13.5 2.0 2.8 2 1 0 2 2 2 0 Cyclin, C-terminal domain Peptidase_S8 PF00082.22 CAR23873.1 - 1.2e-15 57.6 3.3 2.4e-15 56.6 3.3 1.4 1 1 0 1 1 1 1 Subtilase family TIMELESS PF04821.14 CAR23874.1 - 2.4e-90 302.6 0.3 2.4e-90 302.6 0.3 1.9 2 0 0 2 2 2 1 Timeless protein Aa_trans PF01490.18 CAR23875.1 - 7.2e-83 278.6 27.6 8.3e-83 278.4 27.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sec2p PF06428.11 CAR23876.1 - 5.1e-29 100.1 12.5 5.1e-29 100.1 12.5 3.1 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Stimulus_sens_1 PF13756.6 CAR23876.1 - 0.019 15.5 5.2 0.041 14.5 0.6 3.1 2 0 0 2 2 2 0 Stimulus-sensing domain Cep57_CLD PF14073.6 CAR23876.1 - 0.17 11.9 31.2 0.083 12.9 13.6 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 FH2 PF02181.23 CAR23877.1 - 9.7e-89 298.1 8.1 9.7e-89 298.1 8.1 3.1 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CAR23877.1 - 2e-45 154.8 0.2 2e-45 154.8 0.2 4.0 4 0 0 4 4 4 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 CAR23877.1 - 1e-31 110.0 1.2 1e-31 110.0 1.2 3.5 3 2 1 4 4 4 1 Diaphanous GTPase-binding Domain AA_permease PF00324.21 CAR23878.1 - 1.4e-142 475.7 43.8 1.6e-142 475.5 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23878.1 - 5.3e-32 111.2 46.4 7.1e-32 110.8 46.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR23879.1 - 9e-133 443.3 45.0 1.1e-132 443.0 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23879.1 - 1.5e-31 109.7 48.7 1.9e-31 109.4 48.7 1.1 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.8 CAR23879.1 - 1.1 8.9 6.2 1.4 8.6 0.5 3.1 3 0 0 3 3 3 0 Intrinsic membrane protein PufX PI3_PI4_kinase PF00454.27 CAR23880.1 - 9e-35 120.7 1.0 2.8e-34 119.0 0.1 2.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CAR23880.1 - 4.8e-20 71.3 0.6 1.7e-19 69.5 0.6 2.1 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 CAR23880.1 - 1.2e-06 28.1 1.9 2.8e-06 26.9 1.9 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CAR23880.1 - 0.042 13.2 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Tam41_Mmp37 PF09139.11 CAR23881.1 - 1.9e-92 310.2 4.6 4e-85 286.1 1.1 2.1 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial Ist1 PF03398.14 CAR23882.1 - 3.7e-50 170.0 3.3 3.7e-50 170.0 3.3 1.4 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway TPR_19 PF14559.6 CAR23883.1 - 2.8e-13 50.2 7.1 0.0046 17.4 0.1 6.7 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR23883.1 - 7.6e-13 47.5 17.4 1.3 9.3 0.0 10.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAR23883.1 - 7.6e-10 39.0 9.8 0.037 14.3 0.1 7.7 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAR23883.1 - 5.1e-09 36.6 4.2 0.071 13.8 0.0 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR23883.1 - 5.7e-07 29.3 14.4 0.021 15.0 0.2 9.2 11 0 0 11 11 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAR23883.1 - 2.6e-06 27.4 11.2 0.031 14.6 0.1 6.8 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR23883.1 - 3.9e-06 26.5 26.1 0.29 11.0 0.0 8.8 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 CAR23883.1 - 3.9e-05 24.0 9.9 2 9.2 0.0 6.1 7 0 0 7 7 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CAR23883.1 - 8e-05 22.7 0.0 4.8 7.4 0.0 4.2 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CAR23883.1 - 0.00032 21.0 4.1 1.1 9.6 0.1 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 CAR23883.1 - 0.00087 18.9 8.4 0.49 10.1 0.0 4.6 5 0 0 5 5 5 2 TPR repeat ANAPC3 PF12895.7 CAR23883.1 - 0.0016 18.6 13.0 0.6 10.4 0.2 5.3 3 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAR23883.1 - 0.0018 18.2 7.5 15 5.9 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR23883.1 - 0.0041 17.8 2.2 68 4.7 0.0 6.1 3 1 4 7 7 7 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CAR23883.1 - 0.0053 17.2 0.9 0.067 13.6 0.2 2.7 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_15 PF13429.6 CAR23883.1 - 0.018 14.3 1.7 6.3 5.9 0.0 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2192 PF09958.9 CAR23883.1 - 1.2 8.7 7.3 0.12 11.8 0.3 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2192) TPPII_N PF12583.8 CAR23883.1 - 5.3 7.6 6.1 32 5.1 0.1 2.9 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal UFD1 PF03152.14 CAR23884.1 - 1.2e-70 236.4 0.0 1.6e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 SQS_PSY PF00494.19 CAR23884.1 - 0.21 11.0 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Squalene/phytoene synthase ArAE_2_N PF10337.9 CAR23885.1 - 2.1e-51 175.4 4.6 2.1e-51 175.4 4.6 2.9 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CAR23885.1 - 3.3e-13 49.9 13.2 3.3e-13 49.9 13.2 2.8 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 CAR23885.1 - 1.3e-08 34.1 1.4 1.3e-06 27.5 0.3 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 CAR23885.1 - 1e-06 28.8 1.9 3.7e-06 26.9 1.9 2.1 1 1 0 1 1 1 1 Aromatic acid exporter family member 2 CRAL_TRIO PF00650.20 CAR23886.1 - 1.9e-34 118.7 0.0 2.6e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR23886.1 - 4.7e-10 39.5 0.3 1.3e-09 38.1 0.1 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CAR23886.1 - 0.16 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DnaJ PF00226.31 CAR23887.1 - 8.7e-15 54.6 1.2 1.1e-14 54.3 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DUF5610 PF18433.1 CAR23887.1 - 0.12 12.9 0.2 0.88 10.1 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5610) YIF1 PF03878.15 CAR23888.1 - 7.1e-77 258.2 6.3 7.1e-77 258.2 6.3 1.5 2 0 0 2 2 2 1 YIF1 Yip1 PF04893.17 CAR23888.1 - 0.0029 17.3 7.7 0.0057 16.4 7.7 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1744 PF08490.12 CAR23889.1 - 1e-133 445.8 2.2 2e-133 444.9 2.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CAR23889.1 - 4.9e-81 272.5 1.5 4.9e-81 272.5 1.5 3.1 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CAR23889.1 - 3.3e-15 55.8 1.7 2e-13 49.9 1.7 2.7 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CAR23889.1 - 1.3e-06 28.3 0.5 8.6e-06 25.6 0.5 2.4 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CAR23889.1 - 1.2e-05 25.4 0.2 0.00027 21.0 0.0 3.3 2 0 0 2 2 2 1 RNase_H superfamily NAPRTase_C PF17956.1 CAR23889.1 - 0.018 15.5 0.1 0.12 12.8 0.0 2.6 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain TRAF6_Z2 PF18048.1 CAR23889.1 - 0.044 13.9 1.2 0.12 12.4 1.2 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 GIT_CC PF16559.5 CAR23889.1 - 0.29 11.0 1.6 6.3 6.7 0.5 3.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor APP_N PF02177.16 CAR23889.1 - 0.48 10.8 7.5 0.87 10.0 0.4 3.3 3 0 0 3 3 3 0 Amyloid A4 N-terminal heparin-binding ORC5_C PF14630.6 CAR23890.1 - 6.2e-63 213.0 0.3 1.1e-62 212.2 0.3 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CAR23890.1 - 1.5e-08 35.2 0.0 3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain CRAL_TRIO_2 PF13716.6 CAR23890.1 - 0.0011 19.2 0.7 0.0038 17.4 0.1 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain NACHT PF05729.12 CAR23890.1 - 0.026 14.4 1.6 0.16 11.9 1.6 2.2 1 1 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CAR23890.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain GYF PF02213.16 CAR23891.1 - 7.8e-09 35.1 1.0 1.6e-08 34.1 1.0 1.6 1 0 0 1 1 1 1 GYF domain CCDC106 PF15794.5 CAR23891.1 - 0.14 11.8 4.6 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Yae1_N PF09811.9 CAR23892.1 - 2.7e-09 36.6 3.8 8.7e-09 34.9 3.8 1.8 1 1 0 1 1 1 1 Essential protein Yae1, N terminal ITI_HC_C PF06668.12 CAR23892.1 - 0.028 14.1 0.1 0.036 13.7 0.1 1.1 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus HMA PF00403.26 CAR23893.1 - 1.9e-10 41.1 0.2 2.3e-10 40.7 0.2 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain zf-C4 PF00105.18 CAR23893.1 - 0.067 13.7 0.0 0.086 13.3 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Dsl1_N PF11988.8 CAR23894.1 - 5.2e-116 387.5 11.3 5.7e-116 387.4 10.0 1.7 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.8 CAR23894.1 - 7.7e-74 247.6 0.9 7.7e-74 247.6 0.9 2.2 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal CENP-B_N PF04218.13 CAR23894.1 - 0.021 14.4 0.2 1.1 9.0 0.0 3.1 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain VASt PF16016.5 CAR23895.1 - 3.8e-15 56.6 0.0 1e-14 55.2 0.0 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CAR23895.1 - 1.2e-13 51.3 3.0 9.9e-13 48.3 0.0 2.9 3 0 0 3 3 3 1 BAR domain of APPL family PH PF00169.29 CAR23895.1 - 1.2e-08 35.4 0.1 3.9e-08 33.8 0.1 2.0 1 0 0 1 1 1 1 PH domain KH_4 PF13083.6 CAR23895.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.7 1 0 0 1 1 1 0 KH domain DUF4570 PF15134.6 CAR23895.1 - 0.58 10.2 3.1 25 4.9 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) PGAP1 PF07819.13 CAR23896.1 - 1.1e-05 25.3 0.0 5.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CAR23896.1 - 2e-05 24.4 0.0 5.8e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 CAR23896.1 - 4.5e-05 23.1 0.0 0.00011 21.9 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CAR23896.1 - 0.00012 22.0 0.0 0.00052 19.9 0.0 2.0 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 CAR23896.1 - 0.019 15.6 0.0 0.039 14.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 CAR23896.1 - 0.026 13.7 0.0 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 CAR23896.1 - 0.036 13.4 0.0 0.3 10.4 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 CAR23896.1 - 0.048 12.9 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3390 PF11870.8 CAR23896.1 - 0.16 12.4 0.4 4.2 7.8 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) RRM_1 PF00076.22 CAR23897.1 - 1.6e-15 56.7 0.0 3.7e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 CAR23897.1 - 2.2e-15 57.3 0.0 3.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAD_binding_3 PF01494.19 CAR23898.1 - 1.6e-22 80.2 0.1 4.7e-10 39.2 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CAR23898.1 - 0.00016 21.0 0.0 0.003 16.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CAR23898.1 - 0.00067 18.8 0.3 0.0024 17.0 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CAR23898.1 - 0.0024 17.5 0.0 0.047 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CAR23898.1 - 0.0037 16.2 0.0 0.31 9.9 0.0 2.8 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 CAR23898.1 - 0.0067 15.7 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CAR23898.1 - 0.007 16.6 0.2 0.014 15.6 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 CAR23898.1 - 0.012 14.7 0.1 0.036 13.1 0.0 1.8 3 0 0 3 3 3 0 Squalene epoxidase FAD_binding_2 PF00890.24 CAR23898.1 - 0.025 13.7 0.7 0.037 13.1 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 CAR23898.1 - 0.045 13.0 0.0 0.24 10.6 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR23898.1 - 0.058 12.1 0.2 0.11 11.1 0.2 1.6 1 1 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 CAR23898.1 - 0.24 10.7 0.3 0.35 10.2 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pterin_bind PF00809.22 CAR23899.1 - 3.8e-57 193.8 1.4 2.1e-54 184.8 0.6 3.1 2 1 0 2 2 2 1 Pterin binding enzyme FolB PF02152.18 CAR23899.1 - 5.8e-43 146.0 0.2 5.2e-20 72.1 0.1 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CAR23899.1 - 2.4e-34 118.2 0.0 5.6e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) zf-CCHC PF00098.23 CAR23900.1 - 5.4e-53 174.8 54.3 1.3e-08 34.5 1.6 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CAR23900.1 - 1.2e-13 50.5 41.1 0.018 14.8 0.4 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 CAR23900.1 - 9.2e-08 31.7 35.7 0.28 10.9 0.1 7.1 4 3 3 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CAR23900.1 - 0.00055 19.8 41.4 1.4 9.0 0.3 7.0 1 1 6 7 7 7 6 Zinc knuckle zf-C2H2_10 PF16588.5 CAR23900.1 - 0.21 11.4 42.2 0.45 10.3 0.7 6.8 7 0 0 7 7 7 0 C2H2 zinc-finger RTC4 PF14474.6 CAR23901.1 - 1.7e-32 112.1 0.0 2.8e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain ANAPC4_WD40 PF12894.7 CAR23902.1 - 2.5e-14 53.3 0.2 0.015 15.6 0.0 5.2 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR23902.1 - 3.6e-14 52.9 3.8 9e-06 26.3 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 CAR23902.1 - 0.009 15.4 0.1 0.086 12.2 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Lactonase PF10282.9 CAR23902.1 - 0.014 14.7 0.0 0.05 12.8 0.0 1.9 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Me-amine-dh_H PF06433.11 CAR23902.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Ge1_WD40 PF16529.5 CAR23902.1 - 0.081 11.9 0.3 0.32 9.9 0.1 2.0 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SdiA-regulated PF06977.11 CAR23902.1 - 0.19 10.9 0.0 0.91 8.7 0.0 2.0 2 0 0 2 2 2 0 SdiA-regulated MRP-L46 PF11788.8 CAR23903.1 - 1.9e-40 138.3 0.2 3e-40 137.7 0.2 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 RRM_1 PF00076.22 CAR23904.1 - 5.4e-07 29.4 0.0 9.7e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 CAR23904.1 - 5.4e-06 27.1 0.0 2.1e-05 25.2 0.0 2.1 2 1 0 2 2 2 1 RNA polymerase II-binding domain. RNA_bind PF08675.11 CAR23904.1 - 0.0021 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain RRM_7 PF16367.5 CAR23904.1 - 0.016 15.3 0.0 0.065 13.4 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif OS-D PF03392.13 CAR23904.1 - 0.031 14.4 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D Zn_clus PF00172.18 CAR23905.1 - 7.1e-06 26.0 11.6 1.5e-05 25.0 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR23905.1 - 1.1e-05 24.6 1.1 3.3e-05 23.1 1.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CAR23906.1 - 2.6e-13 49.6 40.3 3.3e-12 46.0 22.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MHYT PF03707.16 CAR23906.1 - 4 7.7 9.3 4.3 7.6 0.0 4.4 5 0 0 5 5 5 0 Bacterial signalling protein N terminal repeat AAA_23 PF13476.6 CAR23907.1 - 1.7e-30 107.0 22.6 1.7e-30 107.0 22.6 8.0 2 1 1 3 3 2 1 AAA domain Rad50_zn_hook PF04423.14 CAR23907.1 - 1e-15 57.3 4.0 1e-15 57.3 4.0 5.5 5 0 0 5 5 5 1 Rad50 zinc hook motif AAA_15 PF13175.6 CAR23907.1 - 2e-12 47.5 30.9 1.4e-11 44.7 5.5 5.3 1 1 3 4 4 2 2 AAA ATPase domain AAA_21 PF13304.6 CAR23907.1 - 8.6e-12 45.5 7.6 1.7e-05 24.8 0.1 4.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR23907.1 - 5.2e-08 32.6 0.1 5.2e-08 32.6 0.1 3.0 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CAR23907.1 - 2.7e-06 27.5 0.0 7.8e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CAR23907.1 - 0.00045 19.9 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 CAR23907.1 - 0.00051 18.8 0.3 0.014 14.1 0.0 7.2 3 1 4 7 7 5 3 AAA domain ERM PF00769.19 CAR23907.1 - 0.0015 18.4 24.7 0.0015 18.4 24.7 5.8 2 2 1 4 4 3 2 Ezrin/radixin/moesin family AAA_16 PF13191.6 CAR23907.1 - 0.17 12.3 0.0 0.17 12.3 0.0 3.6 5 0 0 5 5 4 0 AAA ATPase domain AAA_22 PF13401.6 CAR23907.1 - 0.32 11.3 0.0 0.32 11.3 0.0 5.8 6 2 1 7 7 7 0 AAA domain AAA_28 PF13521.6 CAR23907.1 - 1.3 9.3 4.5 7.3 6.8 0.4 3.7 3 0 0 3 3 3 0 AAA domain FGGY_C PF02782.16 CAR23908.1 - 3.1e-22 79.3 0.0 7.1e-22 78.1 0.0 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CAR23908.1 - 0.00019 21.1 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Raco_middle PF17651.1 CAR23908.1 - 0.05 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 RACo middle region BcrAD_BadFG PF01869.20 CAR23908.1 - 0.15 11.6 0.0 0.55 9.7 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family RNA_pol_I_A49 PF06870.12 CAR23909.1 - 2.9e-123 411.5 0.6 3.3e-123 411.4 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Zwint PF15556.6 CAR23909.1 - 0.051 13.1 0.8 0.41 10.1 0.0 2.3 2 1 0 2 2 2 0 ZW10 interactor Exo5 PF09810.9 CAR23909.1 - 0.14 11.6 0.3 0.23 10.9 0.3 1.3 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease DnaJ PF00226.31 CAR23910.1 - 4e-18 65.3 0.3 5.6e-18 64.8 0.3 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CAR23910.1 - 2e-15 56.2 2.2 3.8e-15 55.4 2.2 1.5 1 0 0 1 1 1 1 CSL zinc finger Aegerolysin PF06355.13 CAR23910.1 - 0.14 12.2 0.7 2.8 8.0 0.7 2.1 1 1 0 1 1 1 0 Aegerolysin LCAT PF02450.15 CAR23911.1 - 1.4e-07 31.1 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 CAR23911.1 - 5.1e-06 26.4 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CAR23911.1 - 3.4e-05 23.2 0.0 5.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAR23911.1 - 0.00029 20.6 0.0 0.0015 18.3 0.0 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR23911.1 - 0.0004 21.1 0.0 0.00057 20.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 CAR23911.1 - 0.0019 17.8 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 CAR23911.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 CAR23911.1 - 0.0053 16.4 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Ser_hydrolase PF06821.13 CAR23911.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Palm_thioest PF02089.15 CAR23911.1 - 0.0074 16.2 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF503 PF04456.12 CAR23911.1 - 0.079 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF503) LIDHydrolase PF10230.9 CAR23911.1 - 0.084 12.4 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase tRNA-synt_1e PF01406.19 CAR23912.1 - 1.3e-141 471.3 0.1 1.3e-141 471.3 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CAR23912.1 - 2.7e-06 26.4 4.8 5.8e-05 22.0 0.1 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CAR23912.1 - 7.6e-06 24.4 1.2 2.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) NAP PF00956.18 CAR23913.1 - 8.1e-11 41.6 3.5 2.5e-10 40.0 3.5 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) CWC25 PF12542.8 CAR23914.1 - 5.7e-15 56.1 1.0 5.7e-15 56.1 1.0 1.9 1 1 1 2 2 2 1 Pre-mRNA splicing factor Cir_N PF10197.9 CAR23914.1 - 2.6e-12 46.7 9.7 2.6e-12 46.7 9.7 1.8 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR TM1586_NiRdase PF14512.6 CAR23914.1 - 0.011 15.4 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 0 Putative TM nitroreductase SUI1 PF01253.22 CAR23915.1 - 1.7e-26 92.6 0.8 2.2e-26 92.2 0.8 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Glyco_hydro_3 PF00933.21 CAR23915.1 - 0.059 12.7 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Bromo_TP_like PF17027.5 CAR23915.1 - 0.062 13.5 0.1 0.38 10.9 0.0 2.0 1 1 1 2 2 2 0 Histone-fold protein ANTH PF07651.16 CAR23916.1 - 1e-71 241.2 0.0 1e-71 241.2 0.0 2.9 2 1 1 3 3 3 1 ANTH domain Staph_haemo PF05480.11 CAR23916.1 - 0.29 10.9 0.6 0.55 10.0 0.6 1.4 1 0 0 1 1 1 0 Staphylococcus haemolytic protein HofP PF10748.9 CAR23917.1 - 0.015 14.8 0.0 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 DNA utilization proteins HofP Zn_clus PF00172.18 CAR23918.1 - 4.5e-06 26.7 9.2 1.1e-05 25.5 9.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex2_Pex12 PF04757.14 CAR23919.1 - 2e-07 30.8 12.2 6.9e-07 29.1 12.2 1.8 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CAR23919.1 - 2 8.4 9.6 3.2 7.7 9.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Endonuclease_NS PF01223.23 CAR23921.1 - 2.5e-64 217.2 0.0 3e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Adenine_deam_C PF13382.6 CAR23922.1 - 0.085 12.2 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Adenine deaminase C-terminal domain RNase_H2_suC PF08615.11 CAR23923.1 - 1.4e-13 51.2 0.1 1.9e-09 37.8 0.0 2.0 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Orthopox_F8 PF05886.11 CAR23923.1 - 0.017 15.2 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 Orthopoxvirus F8 protein LRR_4 PF12799.7 CAR23924.1 - 0.0025 18.2 7.4 0.94 10.0 1.4 4.4 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) Sec10 PF07393.11 CAR23925.1 - 3.3e-51 174.6 20.0 4.5e-51 174.2 20.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 SwrA PF17423.2 CAR23925.1 - 0.17 11.9 5.2 0.39 10.7 0.0 3.4 3 1 0 3 3 3 0 Swarming motility protein PRP21_like_P PF12230.8 CAR23926.1 - 9.5e-35 120.4 10.7 9.5e-35 120.4 10.7 1.7 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CAR23926.1 - 7.7e-21 73.8 1.9 1.9e-11 43.8 0.6 2.6 2 0 0 2 2 2 2 Surp module Rep_fac-A_C PF08646.10 CAR23926.1 - 0.44 10.3 3.7 0.15 11.8 0.5 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain CRAL_TRIO_2 PF13716.6 CAR23927.1 - 1.4e-31 109.5 0.7 2.5e-31 108.7 0.7 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CAR23927.1 - 2.5e-06 27.4 0.0 8.6e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 CAR23928.1 - 1.9e-41 142.2 0.7 5.2e-41 140.8 0.7 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CAR23928.1 - 1e-14 54.6 0.1 5.4e-14 52.3 0.1 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 CAR23928.1 - 3.7e-05 23.2 0.0 9.2e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR23928.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain SH3_2 PF07653.17 CAR23928.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Aconitase PF00330.20 CAR23929.1 - 9.3e-151 502.9 0.0 1.2e-150 502.6 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR23929.1 - 3.6e-42 143.8 0.0 6.2e-42 143.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CAR23929.1 - 0.041 12.6 0.0 0.076 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF521) SPX PF03105.19 CAR23931.1 - 6.6e-47 161.3 14.6 9.4e-46 157.5 14.6 2.1 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.19 CAR23931.1 - 6.1e-25 88.2 41.6 8.2e-25 87.8 41.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CAR23931.1 - 3.2e-24 85.7 69.9 1.1e-22 80.6 44.7 1.7 1 1 1 2 2 2 2 Citrate transporter Voldacs PF03517.13 CAR23931.1 - 0.19 11.8 1.2 0.41 10.8 1.2 1.5 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling UCH PF00443.29 CAR23932.1 - 1.3e-75 254.2 0.3 2e-75 253.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR23932.1 - 2.1e-10 40.7 6.4 5.4e-05 22.9 0.1 4.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CAR23932.1 - 8.9e-09 35.9 0.1 3.3e-08 34.1 0.1 2.0 1 0 0 1 1 1 1 DUSP domain CW_binding_1 PF01473.20 CAR23932.1 - 0.057 13.8 0.4 0.14 12.5 0.4 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat EF-hand_12 PF17901.1 CAR23932.1 - 0.069 13.6 1.0 0.14 12.7 0.1 2.0 2 0 0 2 2 2 0 EF-hand fold domain PfkB PF00294.24 CAR23933.1 - 2.2e-50 171.7 2.4 4.2e-50 170.8 2.4 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Peripla_BP_2 PF01497.18 CAR23933.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein RNase_PH PF01138.21 CAR23934.1 - 6.5e-27 94.6 0.7 3.2e-25 89.2 0.7 2.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 ELO PF01151.18 CAR23935.1 - 1.5e-60 204.8 23.8 1.9e-60 204.5 23.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Myb_DNA-binding PF00249.31 CAR23936.1 - 8.1e-16 58.0 0.0 5.4e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR23936.1 - 2.8e-05 24.3 1.0 0.13 12.5 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CAR23936.1 - 0.0023 17.8 0.1 0.0023 17.8 0.1 3.1 3 1 1 4 4 4 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CAR23936.1 - 0.043 14.0 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Cdc6_C PF09079.11 CAR23937.1 - 1.9e-11 43.8 0.0 4.7e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA PF00004.29 CAR23937.1 - 1.1e-09 38.8 0.7 7.9e-09 36.0 0.1 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR23937.1 - 3.6e-09 37.0 0.0 1.1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAR23937.1 - 7.5e-08 32.9 0.0 4.4e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 CAR23937.1 - 0.0008 19.4 0.1 0.0054 16.7 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CAR23937.1 - 0.002 18.5 1.4 0.067 13.5 0.1 2.9 3 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 CAR23937.1 - 0.0034 17.2 0.3 0.66 9.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 CAR23937.1 - 0.006 16.1 1.9 1.2 8.6 0.1 3.0 3 1 0 3 3 3 2 P-loop containing dynein motor region DUF2075 PF09848.9 CAR23937.1 - 0.015 14.5 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CAR23937.1 - 0.063 13.0 0.1 0.2 11.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain Beach PF02138.18 CAR23938.1 - 4e-120 400.3 0.1 7e-120 399.6 0.1 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CAR23938.1 - 5.1e-11 42.6 0.0 1.6e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH SOP4 PF17081.5 CAR23939.1 - 1.3e-88 296.0 0.0 1.5e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Suppressor of PMA 1-7 protein Ribosomal_S11 PF00411.19 CAR23940.1 - 3.3e-46 156.2 1.9 4e-46 155.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S8 PF00410.19 CAR23941.1 - 1e-23 83.7 0.2 1.6e-23 83.0 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 Pkinase PF00069.25 CAR23942.1 - 6.8e-45 153.5 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23942.1 - 5.1e-27 94.8 0.0 8.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4299 PF14132.6 CAR23942.1 - 0.0042 16.6 0.5 0.0065 15.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) DUF1541 PF07563.11 CAR23942.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Mannosyl_trans3 PF11051.8 CAR23943.1 - 7.7e-77 258.3 0.0 1e-76 258.0 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Epimerase PF01370.21 CAR23946.1 - 6.7e-21 74.8 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR23946.1 - 5.3e-19 68.3 0.0 7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CAR23946.1 - 4e-15 55.7 0.2 5.5e-14 52.0 0.2 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CAR23946.1 - 9.2e-13 48.3 0.0 2.6e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CAR23946.1 - 3.1e-06 26.5 0.1 5.5e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CAR23946.1 - 3.4e-06 27.1 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CAR23946.1 - 4.2e-06 26.3 0.0 8.9e-05 22.0 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CAR23946.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 CAR23946.1 - 0.00074 19.1 0.0 0.006 16.2 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 CAR23946.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF4889 PF16230.5 CAR23946.1 - 0.045 14.0 0.2 0.13 12.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) RmlD_sub_bind PF04321.17 CAR23946.1 - 0.078 12.1 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain AA_permease PF00324.21 CAR23947.1 - 1.5e-101 340.4 39.8 1.7e-101 340.2 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23947.1 - 9.3e-26 90.6 42.4 1.3e-25 90.2 42.4 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_3 PF00202.21 CAR23948.1 - 2.4e-58 197.8 0.0 3e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III muHD PF10291.9 CAR23949.1 - 4.5e-76 255.8 0.0 7.5e-76 255.0 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain CorA PF01544.18 CAR23949.1 - 0.018 14.4 0.5 0.041 13.2 0.5 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SSB PF00436.25 CAR23951.1 - 1.3e-19 70.2 0.0 1.6e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Gon7 PF08738.10 CAR23952.1 - 5e-43 145.6 0.2 7.9e-43 145.0 0.2 1.3 1 0 0 1 1 1 1 Gon7 family MFS_1 PF07690.16 CAR23953.1 - 1.1e-26 93.6 18.5 1.7e-26 93.0 18.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CAR23953.1 - 8e-05 22.1 0.5 8e-05 22.1 0.5 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3792 PF12670.7 CAR23953.1 - 0.0064 16.6 0.7 0.0064 16.6 0.7 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF3792) DUF4407 PF14362.6 CAR23953.1 - 0.18 11.2 0.3 0.34 10.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF63 PF01889.17 CAR23953.1 - 1.7 8.7 9.1 0.62 10.2 0.5 2.7 2 1 1 3 3 3 0 Membrane protein of unknown function DUF63 Glyco_transf_34 PF05637.12 CAR23954.1 - 2.8e-53 181.1 0.0 3.9e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ATP12 PF07542.11 CAR23955.1 - 1.1e-34 119.3 0.0 2.1e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein Hom_end PF05204.14 CAR23955.1 - 0.11 12.6 0.1 0.39 10.9 0.1 1.8 2 0 0 2 2 2 0 Homing endonuclease Prefoldin_2 PF01920.20 CAR23956.1 - 6.5e-14 51.8 10.4 7.6e-14 51.6 10.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Gemini_AL1_M PF08283.11 CAR23956.1 - 0.015 15.4 0.1 0.037 14.1 0.1 1.7 1 0 0 1 1 1 0 Geminivirus rep protein central domain Meth_synt_2 PF01717.18 CAR23956.1 - 0.021 14.1 0.4 0.029 13.7 0.2 1.4 1 1 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain DUF3338 PF11819.8 CAR23956.1 - 0.077 13.0 7.9 0.55 10.2 1.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3338) Mt_ATP-synt_D PF05873.12 CAR23956.1 - 0.61 9.9 6.6 0.78 9.6 0.4 2.0 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) NPV_P10 PF05531.12 CAR23956.1 - 1.9 9.0 7.0 0.81 10.2 1.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG27 PF09451.10 CAR23957.1 - 1.5e-48 165.9 0.1 2e-48 165.6 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 AMIN PF11741.8 CAR23957.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 AMIN domain Ribosomal_L22 PF00237.19 CAR23958.1 - 8.6e-38 128.7 0.5 1.3e-37 128.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CASP_C PF08172.12 CAR23959.1 - 5.9e-62 209.3 2.7 5.9e-62 209.3 2.7 5.1 1 1 2 3 3 3 1 CASP C terminal DivIC PF04977.15 CAR23959.1 - 0.017 14.9 1.3 0.017 14.9 1.3 7.9 6 2 2 8 8 8 0 Septum formation initiator HOOK PF05622.12 CAR23959.1 - 1.5 6.9 59.2 0.32 9.1 0.2 4.7 2 1 3 5 5 5 0 HOOK protein CENP-F_leu_zip PF10473.9 CAR23959.1 - 7.7 6.5 72.3 0.25 11.4 9.2 6.6 2 1 3 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Leu_zip PF15294.6 CAR23959.1 - 9 5.7 62.3 2.1 7.8 0.1 5.0 3 2 2 5 5 5 0 Leucine zipper SWIRM PF04433.17 CAR23960.1 - 1.5e-28 99.0 0.1 3.3e-28 97.8 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CAR23960.1 - 2e-22 78.9 9.9 7.9e-22 77.0 9.9 2.1 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CAR23960.1 - 2.1e-09 37.4 0.0 4.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR23960.1 - 9e-07 29.1 0.0 2.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain KRE9 PF05390.11 CAR23961.1 - 7.3e-46 155.1 11.9 7.3e-46 155.1 11.9 2.7 2 1 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CAR23961.1 - 1.5e-11 44.9 1.3 1.5e-11 44.9 1.3 2.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ntox37 PF15535.6 CAR23961.1 - 0.11 13.0 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 Bacterial toxin 37 Rep_fac-A_3 PF08661.11 CAR23962.1 - 1.7e-26 92.6 0.0 1.8e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Cadherin PF00028.17 CAR23962.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.3 1 1 0 1 1 1 0 Cadherin domain Peptidase_M20 PF01546.28 CAR23963.1 - 7.6e-36 123.8 0.0 1.1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR23963.1 - 2e-13 50.2 0.0 3.5e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR23963.1 - 0.093 12.4 0.0 0.5 10.0 0.0 2.0 1 1 0 1 1 1 0 Peptidase family M28 STE3 PF02076.15 CAR23964.1 - 3.9e-83 279.0 17.9 5e-83 278.6 17.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor MASE2 PF05230.11 CAR23964.1 - 1.1 9.4 10.2 3.3 7.8 0.6 3.1 3 0 0 3 3 3 0 MASE2 domain CbiN PF02553.15 CAR23964.1 - 1.7 8.7 6.6 30 4.7 0.2 3.6 3 0 0 3 3 3 0 Cobalt transport protein component CbiN DUF2401 PF10287.9 CAR23965.1 - 4.4e-85 284.9 1.7 6.9e-85 284.3 1.7 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CAR23965.1 - 1.7e-21 76.4 0.0 3.8e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SRI PF08236.11 CAR23967.1 - 1.2e-25 89.4 4.0 1.2e-25 89.4 4.0 3.5 3 1 1 4 4 4 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CAR23967.1 - 2e-19 70.6 0.3 2e-19 70.6 0.3 4.7 3 2 0 3 3 3 1 SET domain WW_1 PF18507.1 CAR23967.1 - 6e-19 67.4 2.6 1.6e-18 66.0 2.6 1.8 1 0 0 1 1 1 1 WW domain AWS PF17907.1 CAR23967.1 - 2.1e-15 56.5 10.2 2.1e-15 56.5 10.2 2.4 2 0 0 2 2 2 1 AWS domain WW PF00397.26 CAR23967.1 - 0.036 14.2 0.1 0.067 13.3 0.1 1.5 1 0 0 1 1 1 0 WW domain LMBR1 PF04791.16 CAR23967.1 - 2 7.2 6.4 3 6.7 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Longin_2 PF18639.1 CAR23968.1 - 4.1e-58 195.9 0.0 7.9e-58 195.0 0.0 1.5 1 0 0 1 1 1 1 Yeast longin domain DUF3367 PF11847.8 CAR23968.1 - 0.055 11.3 0.0 0.087 10.7 0.0 1.2 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Zip PF02535.22 CAR23969.1 - 7.9e-24 84.5 14.3 6.1e-23 81.6 14.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter H_PPase PF03030.16 CAR23969.1 - 0.028 13.1 0.2 0.048 12.3 0.0 1.4 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase CitMHS PF03600.16 CAR23969.1 - 0.033 13.4 0.0 0.067 12.4 0.0 1.5 1 1 0 1 1 1 0 Citrate transporter CbtA PF09490.10 CAR23969.1 - 0.22 11.2 0.1 0.22 11.2 0.1 2.4 3 1 0 3 3 3 0 Probable cobalt transporter subunit (CbtA) CD20 PF04103.15 CAR23969.1 - 0.81 9.8 12.1 0.14 12.2 0.7 3.7 3 1 0 4 4 4 0 CD20-like family TssN PF17555.2 CAR23969.1 - 3.5 6.9 6.7 10 5.4 0.1 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN AA_permease PF00324.21 CAR23970.1 - 3.7e-73 246.8 44.9 4.9e-73 246.4 44.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR23970.1 - 2.8e-44 151.6 47.4 3.7e-44 151.2 47.4 1.1 1 0 0 1 1 1 1 Amino acid permease NUC205 PF08168.11 CAR23970.1 - 0.056 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 NUC205 domain DUF423 PF04241.15 CAR23970.1 - 2.5 8.4 7.8 10 6.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF423) GTP_EFTU PF00009.27 CAR23971.1 - 2.4e-38 131.7 0.0 3.5e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CAR23971.1 - 2.5e-15 56.3 0.0 4.9e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CAR23971.1 - 2.6e-14 53.0 0.0 5.8e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFTUD2 PF16004.5 CAR23971.1 - 9.6e-10 39.1 6.3 7.3e-07 29.8 6.3 2.4 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU_D2 PF03144.25 CAR23971.1 - 1.1e-06 29.0 0.0 2.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR23971.1 - 0.00013 22.0 0.1 0.00039 20.5 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 CAR23971.1 - 0.011 15.2 0.2 0.098 12.1 0.2 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit EFG_II PF14492.6 CAR23971.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II RsgA_GTPase PF03193.16 CAR23971.1 - 0.06 13.2 0.1 2.3 8.1 0.2 2.2 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CAR23971.1 - 0.066 13.4 0.0 5.4 7.3 0.0 2.3 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAR23971.1 - 0.11 12.1 0.1 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Ras family Ebp2 PF05890.12 CAR23972.1 - 1.5e-86 290.3 27.3 1.5e-86 290.3 27.3 2.3 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 polyprenyl_synt PF00348.17 CAR23973.1 - 3.1e-98 327.9 0.0 3.7e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DIT1_PvcA PF05141.12 CAR23973.1 - 0.091 12.2 0.1 0.23 10.9 0.1 1.6 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein UcrQ PF02939.16 CAR23974.1 - 4e-32 110.0 0.8 4.5e-32 109.8 0.8 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CAR23974.1 - 0.0053 17.1 0.1 0.0067 16.8 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Pkinase PF00069.25 CAR23975.1 - 5.5e-38 130.8 0.0 9.9e-25 87.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23975.1 - 2.3e-23 82.8 0.0 3.8e-20 72.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR23975.1 - 0.045 12.5 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CAR23975.1 - 0.064 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L14 PF00238.19 CAR23976.1 - 7.7e-43 145.5 2.5 8.6e-43 145.3 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 CAR23977.1 - 7.6e-43 146.8 0.0 3.8e-42 144.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23977.1 - 2.4e-20 72.9 0.0 4.5e-20 72.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR23977.1 - 0.01 15.2 0.0 0.043 13.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CAR23977.1 - 0.017 14.4 0.2 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CAR23977.1 - 0.077 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 CAR23977.1 - 0.19 11.6 0.1 0.35 10.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family LrgB PF04172.16 CAR23978.1 - 3.3e-44 151.0 5.0 3.3e-44 151.0 5.0 2.3 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 CAR23978.1 - 0.0003 20.7 3.1 0.0003 20.7 3.1 2.5 2 0 0 2 2 2 1 LrgA family L51_S25_CI-B8 PF05047.16 CAR23979.1 - 6e-14 51.7 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FACT-Spt16_Nlob PF14826.6 CAR23979.1 - 0.038 13.8 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain Arf PF00025.21 CAR23979.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family Na_H_Exchanger PF00999.21 CAR23980.1 - 5.4e-30 104.4 37.5 8.8e-21 74.1 26.9 2.0 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Phenol_hyd_sub PF06099.11 CAR23980.1 - 0.18 11.8 1.3 0.39 10.8 1.3 1.5 1 0 0 1 1 1 0 Phenol hydroxylase subunit Pkinase PF00069.25 CAR23982.1 - 1.1e-71 241.3 0.0 1.3e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR23982.1 - 2.1e-40 138.6 0.0 2.8e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR23982.1 - 0.00037 19.9 0.0 0.00095 18.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CAR23982.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAR23982.1 - 0.02 13.9 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain BNR_4 PF15892.5 CAR23982.1 - 0.032 13.6 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 BNR repeat-containing family member MFS_1 PF07690.16 CAR23983.1 - 9.3e-19 67.5 35.9 2.1e-17 63.1 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PigN PF04987.14 CAR23984.1 - 1.3e-128 429.8 42.7 1.9e-128 429.2 42.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CAR23984.1 - 3.5e-12 46.6 1.3 1.1e-09 38.4 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CAR23984.1 - 2e-10 40.6 0.0 6.4e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CAR23984.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily DnaJ PF00226.31 CAR23985.1 - 1.5e-20 73.1 0.3 3.5e-20 71.9 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain PIR PF00399.19 CAR23987.1 - 7.5e-59 194.2 129.4 7.3e-08 31.8 9.8 8.6 8 0 0 8 8 8 8 Yeast PIR protein repeat TFIIA PF03153.13 CAR23987.1 - 6.6 6.6 20.4 9.6 6.1 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIR PF00399.19 CAR23988.1 - 2.6e-67 221.1 151.7 7.9e-08 31.7 9.8 9.6 9 0 0 9 9 9 9 Yeast PIR protein repeat UPF0257 PF06788.13 CAR23988.1 - 1.5 8.6 7.2 20 4.9 0.1 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0257) Ribosomal_S5 PF00333.20 CAR23988.1 - 3.4 7.7 6.8 51 4.0 0.1 3.7 2 1 0 3 3 3 0 Ribosomal protein S5, N-terminal domain PIR PF00399.19 CAR23989.1 - 2.9e-11 42.6 25.0 7.3e-06 25.4 9.8 2.8 2 0 0 2 2 2 2 Yeast PIR protein repeat zf-RING_2 PF13639.6 CAR23990.1 - 0.0096 16.2 6.6 0.028 14.8 6.6 1.9 1 0 0 1 1 1 1 Ring finger domain PH_10 PF15411.6 CAR23990.1 - 0.059 13.6 0.3 0.99 9.7 0.2 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain zf-C3HC4 PF00097.25 CAR23990.1 - 0.16 11.8 5.6 0.51 10.3 5.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR23990.1 - 0.36 10.6 10.1 0.14 12.0 6.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger Peptidase_S64 PF08192.11 CAR23991.1 - 8.1e-279 927.0 0.0 9.9e-279 926.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S64 6PF2K PF01591.18 CAR23992.1 - 3.7e-82 274.9 0.0 5.2e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CAR23992.1 - 1.1e-37 129.7 0.0 1.4e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CAR23992.1 - 0.00026 21.2 0.0 0.00051 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAR23992.1 - 0.058 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CAR23992.1 - 0.058 12.8 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Vps35 PF03635.17 CAR23993.1 - 7.3e-277 920.7 19.2 8.5e-277 920.5 19.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 peroxidase PF00141.23 CAR23994.1 - 1.5e-44 152.4 0.0 2.7e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Mad3_BUB1_I PF08311.12 CAR23994.1 - 0.028 14.4 0.6 0.14 12.2 0.2 2.3 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 Pam17 PF08566.10 CAR23995.1 - 1.4e-66 223.4 0.4 1.7e-66 223.1 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 MFS_1 PF07690.16 CAR23995.1 - 0.0011 18.0 0.1 0.0013 17.7 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Pmp3 PF01679.17 CAR23996.1 - 2.8e-16 59.4 7.2 3.7e-16 59.1 7.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator AftA_N PF12250.8 CAR23996.1 - 0.0015 17.4 0.0 0.0018 17.1 0.0 1.0 1 0 0 1 1 1 1 Arabinofuranosyltransferase N terminal DUF4131 PF13567.6 CAR23996.1 - 0.037 13.7 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) F-box-like PF12937.7 CAR23997.1 - 4.3e-09 36.1 0.2 2.5e-08 33.7 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CAR23997.1 - 1.9e-05 24.4 0.9 6.3e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 F-box domain VIT_2 PF13757.6 CAR23997.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Zn_clus PF00172.18 CAR23998.1 - 2.4e-08 33.9 6.8 6.4e-08 32.6 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR23998.1 - 1.5e-06 27.4 0.4 2.7e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Las1 PF04031.13 CAR23999.1 - 4.2e-47 160.1 0.1 1.1e-46 158.8 0.1 1.7 1 0 0 1 1 1 1 Las1-like RNA_polI_A34 PF08208.11 CAR24000.1 - 1.3e-17 64.6 0.1 1.3e-17 64.6 0.1 2.0 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.9 CAR24000.1 - 0.015 15.3 27.7 0.021 14.8 27.7 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_pol_Rpc4 PF05132.14 CAR24000.1 - 0.094 13.1 8.8 0.1 13.0 8.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Coilin_N PF15862.5 CAR24000.1 - 0.14 12.0 13.7 0.19 11.6 13.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus SR-25 PF10500.9 CAR24000.1 - 0.17 11.4 19.1 0.24 11.0 19.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.14 CAR24000.1 - 0.18 10.1 7.6 0.15 10.3 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CAR24000.1 - 0.41 10.4 11.6 0.45 10.3 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ETRAMP PF09716.10 CAR24000.1 - 0.99 9.5 5.7 1.3 9.1 5.7 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Zip PF02535.22 CAR24000.1 - 6.2 5.9 8.0 6.6 5.8 8.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TFA2_Winged_2 PF18121.1 CAR24001.1 - 5.3e-22 77.3 0.2 1.4e-21 75.9 0.1 1.8 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CAR24001.1 - 1.1e-15 57.6 0.5 2.5e-15 56.5 0.5 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain SNX17_FERM_C PF18116.1 CAR24003.1 - 0.018 15.1 0.1 0.066 13.3 0.1 2.0 2 0 0 2 2 2 0 Sorting Nexin 17 FERM C-terminal domain CRAL_TRIO PF00650.20 CAR24004.1 - 5.8e-23 81.4 0.0 8.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR24004.1 - 0.0074 16.5 0.1 0.028 14.6 0.1 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain BATS PF06968.13 CAR24005.1 - 3.9e-22 78.2 0.0 9.7e-22 76.9 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CAR24005.1 - 7.2e-17 62.3 0.1 4.3e-16 59.7 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Tim17 PF02466.19 CAR24007.1 - 3.1e-30 104.8 5.5 4.1e-30 104.4 5.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 CAR24008.1 - 4.7e-48 163.8 0.0 1.2e-47 162.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24008.1 - 9.9e-20 70.9 0.0 1.5e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR24008.1 - 0.0044 17.0 0.1 0.0082 16.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAR24008.1 - 0.017 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 CAR24008.1 - 0.12 12.0 0.6 0.21 11.1 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.16 CAR24009.1 - 7.9e-35 119.9 6.4 1.5e-34 119.0 6.4 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 PTN13_u3 PF16599.5 CAR24009.1 - 0.0063 16.6 0.6 0.0087 16.1 0.2 1.5 2 0 0 2 2 2 1 Unstructured linker region on PTN13 protein between PDZ Ribonuc_L-PSP PF01042.21 CAR24009.1 - 0.11 12.5 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Endoribonuclease L-PSP Glyco_transf_15 PF01793.16 CAR24010.1 - 4.8e-109 364.5 6.9 5.9e-109 364.2 6.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L1 PF00687.21 CAR24011.1 - 1.9e-43 148.6 0.7 2.3e-43 148.3 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cohesin_HEAT PF12765.7 CAR24011.1 - 0.09 13.1 0.1 12 6.3 0.0 2.8 2 1 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DEAD PF00270.29 CAR24012.1 - 1.9e-45 154.7 1.2 2.1e-45 154.7 0.3 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR24012.1 - 8e-31 106.7 0.4 4.2e-30 104.3 0.2 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR24012.1 - 5.7e-07 29.7 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CAR24012.1 - 0.0035 17.1 0.1 0.007 16.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR24012.1 - 0.0039 17.5 0.1 0.082 13.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 CAR24012.1 - 0.034 13.5 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Glyco_transf_8 PF01501.20 CAR24013.1 - 1.4e-22 80.5 0.0 2.7e-22 79.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 GSH_synth_ATP PF03917.17 CAR24013.1 - 0.23 10.2 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain Ribosomal_S21e PF01249.18 CAR24014.1 - 2.6e-40 136.4 0.0 2.9e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e VCH_CASS14 PF18315.1 CAR24014.1 - 0.15 12.1 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain tRNA_U5-meth_tr PF05958.11 CAR24015.1 - 1.2e-22 80.4 0.1 2.9e-21 75.9 0.1 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 CAR24015.1 - 1.1e-11 44.6 0.0 3.9e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_31 PF13847.6 CAR24015.1 - 5.4e-07 29.5 0.0 9.9e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR24015.1 - 5.4e-06 27.0 0.1 1.3e-05 25.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CAR24015.1 - 1.4e-05 24.6 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CAR24015.1 - 0.00015 21.4 0.1 0.00027 20.5 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CAR24015.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 CAR24015.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 CAR24015.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CAR24015.1 - 0.049 14.3 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 CAR24015.1 - 0.062 12.8 0.0 0.5 9.8 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Ras PF00071.22 CAR24016.1 - 1e-48 165.0 0.0 1.3e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24016.1 - 3.4e-23 82.1 0.0 5.5e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24016.1 - 3.7e-05 23.2 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_6 PF12774.7 CAR24017.1 - 1.7e-110 369.0 0.3 6.3e-109 363.9 0.0 3.4 3 1 1 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAR24017.1 - 3.3e-77 260.3 4.6 3.3e-77 260.3 4.6 5.4 6 1 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CAR24017.1 - 9.3e-62 209.4 0.3 9.3e-62 209.4 0.3 4.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CAR24017.1 - 2.2e-55 187.2 4.3 3.6e-54 183.2 0.0 4.1 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 CAR24017.1 - 6.8e-46 156.7 0.0 3.1e-45 154.5 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CAR24017.1 - 6.3e-40 136.6 0.0 1.4e-34 119.2 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CAR24017.1 - 4.8e-30 104.8 2.5 9.2e-30 103.8 2.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CAR24017.1 - 1.1e-21 77.3 0.0 9.9e-10 38.6 0.0 6.0 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 CAR24017.1 - 1.6e-20 73.4 0.1 1.6e-20 73.4 0.1 3.0 3 0 0 3 3 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CAR24017.1 - 1.7e-19 70.3 0.0 1.9e-18 66.8 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CAR24017.1 - 4.3e-17 62.8 1.1 0.00036 21.0 0.0 6.8 5 1 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR24017.1 - 1.4e-11 44.8 2.7 0.023 15.0 0.0 6.5 6 0 0 6 6 5 3 AAA domain AAA_lid_1 PF17857.1 CAR24017.1 - 2.3e-10 40.6 0.1 4.1e-09 36.6 0.1 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_18 PF13238.6 CAR24017.1 - 2.1e-09 38.0 0.2 0.17 12.4 0.0 5.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CAR24017.1 - 8.3e-08 32.8 2.0 0.47 10.8 0.0 7.1 7 0 0 7 7 7 1 AAA ATPase domain Dynein_AAA_lid PF17852.1 CAR24017.1 - 8.2e-07 29.2 1.0 1.7e-05 24.9 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_19 PF13245.6 CAR24017.1 - 3.5e-06 27.4 0.3 0.23 11.8 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CAR24017.1 - 1.1e-05 25.2 0.1 0.37 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CAR24017.1 - 1.4e-05 24.3 0.0 0.051 12.6 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_33 PF13671.6 CAR24017.1 - 0.00043 20.5 0.1 6.9 6.8 0.0 4.1 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CAR24017.1 - 0.0016 18.2 2.6 10 5.8 0.0 4.3 4 0 0 4 4 4 0 AAA domain cobW PF02492.19 CAR24017.1 - 0.0028 17.3 0.1 1.3 8.6 0.0 2.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 CAR24017.1 - 0.0048 16.7 0.3 10 5.8 0.0 3.7 4 0 0 4 4 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CAR24017.1 - 0.016 15.6 0.0 34 4.9 0.0 4.0 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.6 CAR24017.1 - 0.02 15.1 2.0 5.3 7.3 0.1 3.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CAR24017.1 - 0.033 13.5 0.0 2.9 7.1 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin NitrOD2 PF18550.1 CAR24017.1 - 0.04 14.0 0.0 0.41 10.8 0.0 2.7 3 0 0 3 3 2 0 Nitrososphaera output domain 2 AAA_29 PF13555.6 CAR24017.1 - 0.043 13.6 0.0 9.3 6.1 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CAR24017.1 - 0.043 13.2 0.3 14 4.9 0.0 3.3 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CAR24017.1 - 0.045 13.3 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CAR24017.1 - 0.046 13.7 0.6 3.3 7.7 0.0 3.4 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 CAR24017.1 - 0.14 12.1 1.5 3.6 7.6 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CAR24017.1 - 0.16 11.7 0.0 6.2 6.6 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 CAR24017.1 - 0.49 10.3 2.3 3.5 7.5 0.0 3.0 3 0 0 3 3 2 0 NTPase SRPRB PF09439.10 CAR24017.1 - 2.1 7.7 5.1 37 3.7 0.0 4.6 6 0 0 6 6 4 0 Signal recognition particle receptor beta subunit PAP2 PF01569.21 CAR24018.1 - 8.9e-18 64.4 5.3 1.8e-17 63.4 5.3 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CAR24018.1 - 0.037 13.7 7.7 0.095 12.4 7.7 1.8 1 1 0 1 1 1 0 PAP2 superfamily Mito_carr PF00153.27 CAR24020.1 - 5e-60 199.4 2.1 1.6e-21 76.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Solute_trans_a PF03619.16 CAR24021.1 - 1e-74 251.4 16.6 1.3e-74 251.1 16.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF5325 PF17259.2 CAR24021.1 - 4.3 7.3 4.7 24 4.9 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5325) Zn_dep_PLPC PF00882.18 CAR24022.1 - 9.5e-24 84.4 1.1 1.7e-23 83.6 1.1 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C FG-GAP PF01839.23 CAR24022.1 - 6.1e-05 23.1 0.2 0.013 15.6 0.1 3.2 2 0 0 2 2 2 1 FG-GAP repeat FG-GAP_2 PF14312.6 CAR24022.1 - 0.015 15.6 2.6 6.6 7.1 0.0 4.1 4 0 0 4 4 4 0 FG-GAP repeat VCBS PF13517.6 CAR24022.1 - 0.022 15.3 0.4 0.14 12.7 0.2 2.5 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Mub_B2 PF17966.1 CAR24022.1 - 0.17 12.6 0.0 0.34 11.6 0.0 1.5 1 0 0 1 1 1 0 Mub B2-like domain TcdB_toxin_midN PF12256.8 CAR24022.1 - 0.19 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region mIF3 PF14877.6 CAR24023.1 - 7.7e-63 211.3 10.3 7.7e-63 211.3 10.3 2.4 3 0 0 3 3 3 1 Mitochondrial translation initiation factor MotY_N PF18393.1 CAR24023.1 - 0.11 12.6 0.9 0.44 10.7 0.1 2.3 2 0 0 2 2 2 0 MotY N-terminal domain CPSase_L_D2 PF02786.17 CAR24024.1 - 8.3e-113 375.1 1.8 1.6e-83 279.3 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CAR24024.1 - 8.4e-49 164.7 0.0 2.1e-48 163.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 CAR24024.1 - 6.8e-45 152.7 0.0 1.7e-44 151.4 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 CAR24024.1 - 4.4e-44 150.5 0.0 1.1e-43 149.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CAR24024.1 - 6.8e-39 133.0 0.5 3e-38 130.9 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CAR24024.1 - 2.7e-30 105.5 0.1 5.2e-29 101.3 0.0 3.2 4 0 0 4 4 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CAR24024.1 - 3e-22 78.6 0.0 1.7e-21 76.2 0.0 2.5 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CAR24024.1 - 4e-16 59.2 3.5 2.1e-09 37.2 0.7 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAR24024.1 - 3.7e-14 52.6 0.7 9.3e-07 28.6 0.2 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CAR24024.1 - 7.7e-12 45.1 0.1 1.4e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 CAR24024.1 - 1e-05 25.4 0.0 0.0011 18.8 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 CAR24024.1 - 2.6e-05 24.4 1.5 0.047 13.7 0.3 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 CAR24024.1 - 0.00012 22.0 0.5 0.006 16.4 0.0 3.6 5 0 0 5 5 5 1 DJ-1/PfpI family TrkA_N PF02254.18 CAR24024.1 - 0.39 11.0 2.8 0.55 10.5 0.1 2.8 3 0 0 3 3 3 0 TrkA-N domain TrkH PF02386.16 CAR24025.1 - 8.3e-169 562.2 2.9 8.3e-169 562.2 2.9 2.0 2 0 0 2 2 2 2 Cation transport protein Pkinase PF00069.25 CAR24026.1 - 1.6e-58 198.2 0.0 2.1e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24026.1 - 1.1e-36 126.5 0.0 1.4e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR24026.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pro_isomerase PF00160.21 CAR24026.1 - 0.14 12.5 0.2 0.25 11.6 0.2 1.4 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase_fungal PF17667.1 CAR24026.1 - 0.22 10.3 0.4 0.38 9.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase DUF4332 PF14229.6 CAR24026.1 - 0.3 11.3 2.4 6 7.1 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) PNGaseA PF12222.8 CAR24027.1 - 1.1e-89 301.3 2.3 1.1e-89 301.3 2.3 1.4 2 0 0 2 2 2 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A OapA_N PF08525.11 CAR24027.1 - 0.024 14.6 0.3 0.04 13.9 0.3 1.4 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif zf-H2C2 PF09337.10 CAR24028.1 - 1.8e-14 53.6 2.5 3.7e-14 52.7 2.5 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 CAR24028.1 - 6.1e-11 42.3 0.5 1.3e-10 41.2 0.5 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 CAR24028.1 - 6.9e-05 23.1 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 CAR24028.1 - 0.0055 17.4 0.0 0.011 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1719 PF08224.11 CAR24028.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) CN_hydrolase PF00795.22 CAR24029.1 - 2.3e-53 181.2 0.0 2.7e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCD14 PF08704.10 CAR24030.1 - 2.6e-82 276.2 0.7 2.3e-45 155.2 0.1 2.3 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 CAR24030.1 - 5e-06 26.3 0.0 2.2e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term RrnaAD PF00398.20 CAR24030.1 - 0.00056 19.1 0.0 0.0024 17.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 CAR24030.1 - 0.0016 18.3 0.1 0.0072 16.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR24030.1 - 0.0032 18.2 0.0 0.0084 16.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.13 CAR24030.1 - 0.013 14.7 0.3 0.034 13.3 0.0 1.8 2 1 0 2 2 2 0 Gcd10p family PCMT PF01135.19 CAR24030.1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ABC_tran_Xtn PF12848.7 CAR24030.1 - 0.074 13.1 3.0 0.2 11.7 3.0 1.7 1 0 0 1 1 1 0 ABC transporter Methyltransf_23 PF13489.6 CAR24030.1 - 0.11 12.3 0.1 0.26 11.1 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 CAR24031.1 - 5.5e-15 54.8 0.2 8.5e-15 54.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain PUF PF00806.19 CAR24031.1 - 0.076 12.7 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat DUF1687 PF07955.11 CAR24032.1 - 1.2e-26 93.7 0.1 1.7e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DUF5427 PF10310.9 CAR24033.1 - 1e-111 374.2 13.9 1.2e-111 374.0 13.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) MARCKS PF02063.17 CAR24033.1 - 0.0013 18.8 22.9 0.0013 18.8 22.9 1.6 2 0 0 2 2 2 1 MARCKS family Alb1 PF09135.11 CAR24034.1 - 1.4e-18 67.7 9.0 2.1e-18 67.1 9.0 1.2 1 0 0 1 1 1 1 Alb1 ALC PF17527.2 CAR24034.1 - 0.41 10.3 3.1 1.9 8.1 0.6 2.1 2 0 0 2 2 2 0 Phage ALC protein Ribul_P_3_epim PF00834.19 CAR24035.1 - 1.3e-65 220.5 0.1 1.7e-65 220.1 0.1 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CAR24035.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 CAR24035.1 - 0.11 12.3 0.0 0.5 10.1 0.0 1.9 2 1 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain NAP PF00956.18 CAR24036.1 - 1.1e-88 296.9 7.5 1.1e-88 296.9 7.5 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) BUD22 PF09073.10 CAR24036.1 - 0.68 9.2 24.4 1.6 8.0 19.7 2.1 2 0 0 2 2 2 0 BUD22 PET10 PF17316.2 CAR24037.1 - 2e-100 335.5 0.1 2.5e-100 335.1 0.1 1.1 1 0 0 1 1 1 1 Petite colonies protein 10 AMMECR1 PF01871.17 CAR24038.1 - 6.3e-38 130.0 0.0 6.9e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Pho86 PF11124.8 CAR24040.1 - 1e-102 343.5 1.7 1.2e-102 343.4 1.7 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 CLN6 PF15156.6 CAR24040.1 - 0.0017 17.7 0.3 0.0024 17.2 0.3 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 6 Lectin_leg-like PF03388.13 CAR24041.1 - 6.7e-09 35.4 0.0 6.2e-05 22.5 0.0 2.1 2 0 0 2 2 2 2 Legume-like lectin family Bact_lectin PF18483.1 CAR24041.1 - 2.1e-06 27.9 0.2 3.4e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Bacterial lectin SH3_1 PF00018.28 CAR24041.1 - 0.11 12.2 0.3 0.22 11.1 0.3 1.4 1 0 0 1 1 1 0 SH3 domain His_Phos_1 PF00300.22 CAR24042.1 - 7.3e-34 117.2 0.1 9.7e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SUN PF03856.13 CAR24044.1 - 3.6e-99 331.2 15.1 4.5e-99 330.9 15.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) CCDC24 PF15669.5 CAR24044.1 - 0.067 13.1 6.5 0.098 12.5 6.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family AMP_N PF05195.16 CAR24044.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Mg_trans_NIPA PF05653.14 CAR24045.1 - 6.8e-15 54.9 16.0 9.2e-15 54.5 16.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CAR24045.1 - 0.8 9.9 21.9 0.11 12.7 4.6 2.9 2 2 0 2 2 2 0 EamA-like transporter family ASF1_hist_chap PF04729.13 CAR24046.1 - 2.4e-71 238.7 0.0 3.6e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone BUD22 PF09073.10 CAR24046.1 - 1.7 7.9 42.7 2.1 7.6 42.7 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CAR24046.1 - 6.8 4.8 48.3 9.9 4.2 48.3 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 CAR24048.1 - 2.8e-52 177.7 0.0 4.6e-52 177.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24048.1 - 5.7e-20 71.7 0.0 9.7e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CAR24048.1 - 0.0012 18.6 0.1 0.55 9.8 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAR24048.1 - 0.0084 16.0 0.0 5.3 6.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CAR24048.1 - 0.0092 15.3 0.0 0.44 9.8 0.0 2.3 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CAR24048.1 - 0.076 12.6 0.2 0.18 11.4 0.2 1.7 1 0 0 1 1 1 0 RIO1 family Actin PF00022.19 CAR24049.1 - 4.6e-108 361.4 0.0 1.5e-107 359.8 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAR24049.1 - 0.0042 15.9 0.0 0.029 13.2 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Adap_comp_sub PF00928.21 CAR24051.1 - 8.1e-78 261.4 0.5 1.1e-77 261.0 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 CAR24051.1 - 0.013 15.0 0.1 0.075 12.5 0.1 2.0 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Pribosyl_synth PF14572.6 CAR24052.1 - 1.2e-43 149.3 0.3 2e-43 148.6 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CAR24052.1 - 2.8e-36 124.0 0.0 1.6e-35 121.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CAR24052.1 - 1.1e-13 50.9 1.0 4.4e-13 49.0 0.9 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAR24052.1 - 0.005 16.3 0.1 0.0085 15.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pkinase PF00069.25 CAR24053.1 - 3.8e-51 174.0 0.0 6.6e-51 173.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24053.1 - 5.7e-23 81.5 0.0 1.1e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CAR24053.1 - 0.0016 18.1 0.9 0.0043 16.7 0.1 2.1 2 1 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 CAR24053.1 - 0.0023 17.3 0.0 0.011 15.1 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CAR24053.1 - 0.045 13.7 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family MBD_C PF14048.6 CAR24053.1 - 0.12 13.1 1.6 0.69 10.6 1.3 2.2 1 1 1 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF21 PF01595.20 CAR24054.1 - 1.5e-33 115.9 0.2 6.5e-33 113.9 0.2 1.9 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CAR24054.1 - 5.5e-06 26.7 0.0 0.21 12.1 0.0 3.1 2 0 0 2 2 2 2 CBS domain NAD_Gly3P_dh_N PF01210.23 CAR24055.1 - 6.2e-53 179.0 0.1 1.1e-52 178.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CAR24055.1 - 1.3e-40 139.0 0.1 2.3e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CAR24055.1 - 0.0031 18.1 0.0 0.71 10.5 0.0 2.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CYLD_phos_site PF16607.5 CAR24055.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured IlvN PF07991.12 CAR24055.1 - 0.13 11.8 0.2 0.81 9.2 0.0 2.3 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Arginosuc_synth PF00764.19 CAR24056.1 - 3.5e-163 543.4 0.0 4.1e-163 543.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CAR24056.1 - 0.00035 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CAR24056.1 - 0.0035 16.2 0.1 0.0055 15.5 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CAR24056.1 - 0.068 12.8 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Peptidase_M49 PF03571.15 CAR24057.1 - 3.5e-236 784.9 0.0 6.7e-236 783.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M49 His_Phos_1 PF00300.22 CAR24058.1 - 4e-32 111.5 0.0 4.3e-15 55.9 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) zf-C2H2 PF00096.26 CAR24059.1 - 0.00058 20.2 7.9 0.0019 18.6 0.4 3.1 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR24059.1 - 0.0055 17.4 5.7 0.22 12.5 0.0 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CAR24059.1 - 0.033 14.5 0.8 0.16 12.3 0.9 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding BUD22 PF09073.10 CAR24059.1 - 4 6.7 15.0 6.5 6.0 15.0 1.3 1 0 0 1 1 1 0 BUD22 Phos_pyr_kin PF08543.12 CAR24060.1 - 1e-71 241.2 0.0 1.3e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CAR24060.1 - 2.1e-47 161.7 0.2 3e-47 161.1 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CAR24060.1 - 1.7e-07 30.8 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Asp PF00026.23 CAR24061.1 - 9.1e-63 212.6 2.6 9.1e-63 212.6 2.6 2.4 3 0 0 3 3 3 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR24061.1 - 9.1e-09 35.8 0.1 9.1e-09 35.8 0.1 3.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal F-box-like PF12937.7 CAR24062.1 - 2.2e-14 53.1 0.1 5e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR24062.1 - 3.4e-10 39.5 0.1 6.8e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CAR24062.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 F-box PRANC PF09372.10 CAR24062.1 - 0.019 15.2 0.0 0.047 14.0 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Elongin_A PF06881.11 CAR24062.1 - 0.033 14.7 0.1 0.033 14.7 0.1 2.4 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF2508 PF10704.9 CAR24062.1 - 0.32 11.2 3.2 5.2 7.3 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) FAD_binding_6 PF00970.24 CAR24063.1 - 3.2e-30 104.4 0.0 5e-30 103.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CAR24063.1 - 3.5e-26 92.0 0.0 4.8e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CAR24063.1 - 3.5e-05 24.0 0.0 5.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4131 PF13567.6 CAR24063.1 - 0.064 12.9 0.1 0.16 11.6 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) ALO PF04030.14 CAR24064.1 - 2.2e-101 339.1 0.3 3e-101 338.6 0.3 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CAR24064.1 - 4.5e-27 94.5 0.1 6.5e-27 94.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain UPF0180 PF03698.13 CAR24064.1 - 0.019 15.1 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Tubulin PF00091.25 CAR24065.1 - 6.2e-67 225.6 0.0 9e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAR24065.1 - 5e-50 168.9 0.1 7.7e-50 168.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.24 CAR24066.1 - 1.3e-47 162.7 17.0 1.6e-47 162.4 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR24066.1 - 4e-20 72.1 19.6 4.2e-13 49.0 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SQS_PSY PF00494.19 CAR24067.1 - 1.1e-39 136.5 0.0 1.4e-39 136.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Pept_tRNA_hydro PF01195.19 CAR24068.1 - 1.9e-35 122.4 0.0 2.2e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Gtr1_RagA PF04670.12 CAR24069.1 - 1.6e-95 318.9 2.3 1.6e-95 318.9 2.3 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CAR24069.1 - 2.4e-09 37.0 0.9 3.6e-09 36.4 0.2 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CAR24069.1 - 7.2e-09 35.9 0.3 2.8e-08 34.0 0.1 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24069.1 - 1.6e-08 34.2 1.0 5.2e-08 32.5 0.1 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR24069.1 - 1.3e-07 31.7 0.0 3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Guanylate_kin PF00625.21 CAR24069.1 - 0.0077 15.9 2.4 0.017 14.8 0.7 2.3 2 1 0 2 2 2 1 Guanylate kinase ABC_tran PF00005.27 CAR24069.1 - 0.0093 16.5 0.5 0.023 15.2 0.2 2.0 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CAR24069.1 - 0.036 14.0 3.7 1.2 9.0 0.1 3.0 3 0 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 CAR24069.1 - 0.037 13.3 1.3 0.32 10.3 0.1 2.4 1 1 0 2 2 2 0 AIG1 family DUF815 PF05673.13 CAR24069.1 - 0.04 13.1 0.1 0.076 12.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 CAR24069.1 - 0.049 13.4 0.3 0.098 12.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SopD PF11047.8 CAR24069.1 - 0.19 10.9 5.6 0.032 13.4 1.4 1.7 2 0 0 2 2 2 0 Salmonella outer protein D RNA_pol_L PF01193.24 CAR24069.1 - 0.2 11.1 0.2 1.2 8.6 0.0 2.1 2 1 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pyr_redox_2 PF07992.14 CAR24070.1 - 2.8e-47 161.4 0.0 3.6e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR24070.1 - 1.6e-12 47.8 0.1 1.3e-09 38.5 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR24070.1 - 1.1e-07 31.5 1.4 0.068 12.4 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CAR24070.1 - 0.024 14.0 0.0 4.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DUF1451 PF07295.11 CAR24070.1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Mesothelin PF06060.12 CAR24070.1 - 0.088 11.0 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) baeRF_family3 PF18845.1 CAR24070.1 - 0.09 13.0 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 DAO PF01266.24 CAR24070.1 - 0.15 11.7 0.4 9.7 5.7 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CAR24070.1 - 0.68 9.9 4.4 21 5.1 0.1 3.6 3 1 1 4 4 4 0 FAD-NAD(P)-binding HSP70 PF00012.20 CAR24071.1 - 1.9e-265 881.8 14.3 2.1e-265 881.6 14.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR24071.1 - 7.2e-15 54.6 3.7 7.7e-13 47.9 1.2 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CAR24071.1 - 0.00083 19.1 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Syntaxin_2 PF14523.6 CAR24071.1 - 0.22 11.9 6.4 0.11 12.9 2.7 2.3 1 1 1 2 2 2 0 Syntaxin-like protein YlbD_coat PF14071.6 CAR24071.1 - 0.44 10.8 6.5 1.2 9.4 6.5 1.8 1 0 0 1 1 1 0 Putative coat protein FtsA PF14450.6 CAR24071.1 - 1.2 9.6 8.9 1.6 9.2 0.6 4.0 3 2 0 3 3 3 0 Cell division protein FtsA HXXSHH PF07586.11 CAR24071.1 - 1.2 8.6 6.3 1.9 8.0 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) DUF5321 PF17254.2 CAR24071.1 - 1.4 8.4 8.4 0.039 13.4 0.9 2.3 2 1 1 3 3 3 0 Family of unknown function (DUF5321) Vps55 PF04133.14 CAR24072.1 - 9.9e-44 148.1 8.0 1.1e-43 147.9 8.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 FYVE PF01363.21 CAR24073.1 - 7.7e-17 61.2 13.9 7.7e-17 61.2 13.9 3.1 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CAR24073.1 - 2.6e-08 34.0 3.0 2.6e-08 34.0 3.0 4.2 4 1 1 5 5 5 1 Ring finger domain zf-RING_11 PF17123.5 CAR24073.1 - 2.5e-06 27.1 4.3 2.5e-06 27.1 4.3 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CAR24073.1 - 3e-05 23.9 3.6 3e-05 23.9 3.6 4.1 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR24073.1 - 0.00041 20.1 2.2 0.00041 20.1 2.2 4.7 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR24073.1 - 0.0013 18.6 2.8 0.0013 18.6 2.8 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CAR24073.1 - 0.0044 17.2 1.3 0.0044 17.2 1.3 3.1 3 1 1 4 4 4 1 FANCL C-terminal domain Mut7-C PF01927.16 CAR24073.1 - 0.044 13.9 0.1 0.044 13.9 0.1 2.4 1 1 1 3 3 3 0 Mut7-C RNAse domain zf-RING_5 PF14634.6 CAR24073.1 - 5.6 7.0 30.6 0.41 10.6 3.0 4.5 4 0 0 4 4 4 0 zinc-RING finger domain Pox_A3L PF05288.11 CAR24073.1 - 6.4 6.8 6.8 25 5.0 0.2 3.6 3 0 0 3 3 3 0 Poxvirus A3L Protein Brix PF04427.18 CAR24074.1 - 1.7e-51 175.1 1.0 1.7e-51 175.1 1.0 1.4 2 0 0 2 2 2 1 Brix domain DUF4692 PF15763.5 CAR24074.1 - 1.7 9.1 10.2 0.48 10.9 4.8 2.3 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) DEAD PF00270.29 CAR24075.1 - 2.4e-49 167.5 0.0 4.3e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR24075.1 - 1.5e-29 102.5 0.6 6.8e-29 100.5 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR24075.1 - 6.2e-07 29.6 0.1 2.1e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAR24075.1 - 0.001 19.4 0.2 0.008 16.5 0.0 2.3 3 0 0 3 3 3 1 AAA domain GLTP PF08718.11 CAR24075.1 - 0.015 15.6 3.1 0.17 12.2 0.0 3.3 3 1 0 3 3 3 0 Glycolipid transfer protein (GLTP) BSD PF03909.17 CAR24076.1 - 1.9e-23 82.2 2.1 4.3e-12 45.8 0.5 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 CAR24076.1 - 4.8e-20 71.7 0.1 1.2e-19 70.4 0.1 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF4611 PF15387.6 CAR24076.1 - 0.036 14.3 1.7 0.23 11.7 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SIN1_PH PF16979.5 CAR24076.1 - 0.053 13.8 0.1 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology DUF559 PF04480.12 CAR24076.1 - 0.063 13.1 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF559) GCIP PF13324.6 CAR24076.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting HSP70 PF00012.20 CAR24077.1 - 8e-81 272.0 1.7 8.7e-80 268.6 0.8 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CAR24077.1 - 1.1e-11 44.2 0.0 1.5e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 CAR24077.1 - 0.0029 16.3 0.1 0.062 11.9 0.1 2.1 2 0 0 2 2 2 1 Actin PilM_2 PF11104.8 CAR24077.1 - 0.032 13.3 0.0 4.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; ApbA PF02558.16 CAR24078.1 - 2.7e-29 101.8 0.0 4.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CAR24078.1 - 1.7e-24 86.4 0.0 2.7e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 CAR24078.1 - 0.097 13.3 0.0 0.82 10.3 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Baculo_PEP_C PF04513.12 CAR24079.1 - 0.0045 17.0 8.8 0.0079 16.2 8.8 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CAR24079.1 - 0.31 11.1 4.3 0.89 9.6 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COMMD1_N PF17221.3 CAR24079.1 - 0.35 11.2 1.8 6.6 7.1 0.2 2.9 2 1 1 3 3 3 0 COMMD1 N-terminal domain XhlA PF10779.9 CAR24079.1 - 1.5 9.1 3.2 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Haemolysin XhlA AAA_13 PF13166.6 CAR24079.1 - 6.1 5.4 12.0 0.1 11.2 4.3 1.7 2 0 0 2 2 2 0 AAA domain RNase_P_p30 PF01876.16 CAR24080.1 - 1.1e-74 250.5 0.1 1.4e-74 250.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Med21 PF11221.8 CAR24084.1 - 2e-43 148.1 8.6 2.8e-43 147.6 8.6 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 CAR24084.1 - 0.00013 22.0 4.3 0.00025 21.1 0.7 2.6 1 1 2 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin PF00261.20 CAR24084.1 - 0.0032 16.9 5.3 0.0047 16.3 5.3 1.2 1 0 0 1 1 1 1 Tropomyosin RuvB_N PF05496.12 CAR24084.1 - 0.0096 15.7 0.2 0.013 15.3 0.2 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF3545 PF12065.8 CAR24084.1 - 0.01 15.8 2.0 0.014 15.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) HAP1_N PF04849.13 CAR24084.1 - 0.059 12.6 7.3 0.068 12.4 7.3 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF615 PF04751.14 CAR24084.1 - 0.086 12.8 3.9 0.41 10.6 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF615) V_ATPase_I PF01496.19 CAR24084.1 - 0.35 8.7 2.9 0.42 8.5 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ORF6C PF10552.9 CAR24084.1 - 0.66 10.1 5.3 0.22 11.6 0.8 2.1 2 1 0 2 2 2 0 ORF6C domain DUF1664 PF07889.12 CAR24084.1 - 2.3 8.3 6.4 2.4 8.2 4.7 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 CAR24084.1 - 5.5 7.7 8.3 1.9 9.2 2.2 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF1492 PF07374.11 CAR24084.1 - 6.9 6.9 8.6 18 5.6 1.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) MIR PF02815.19 CAR24085.1 - 1.9e-18 67.0 0.1 3.3e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 MIR domain PMT PF02366.18 CAR24085.1 - 2.4e-15 56.8 18.7 2.4e-15 56.8 18.7 2.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ins145_P3_rec PF08709.11 CAR24085.1 - 0.066 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Inositol 1,4,5-trisphosphate/ryanodine receptor F-box-like_2 PF13013.6 CAR24087.1 - 0.024 14.6 0.0 0.078 13.0 0.0 1.9 1 1 0 1 1 1 0 F-box-like domain F-box-like PF12937.7 CAR24087.1 - 0.1 12.5 1.3 0.29 11.1 1.3 1.8 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 CAR24087.1 - 0.17 12.0 0.5 19 5.6 0.1 4.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 CAR24087.1 - 0.23 11.2 0.9 46 3.9 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat HIT PF01230.23 CAR24088.1 - 1e-25 90.3 1.3 1e-25 90.3 1.3 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CAR24088.1 - 9.3e-06 26.1 1.1 1.4e-05 25.5 1.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CAR24088.1 - 0.049 13.5 0.2 0.088 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 IGR PF09597.10 CAR24089.1 - 1.3e-24 86.0 0.3 2.2e-24 85.3 0.3 1.4 1 0 0 1 1 1 1 IGR protein motif Fip1 PF05182.13 CAR24090.1 - 1.4e-22 78.9 0.6 1.4e-22 78.9 0.6 1.6 2 0 0 2 2 2 1 Fip1 motif TFIIF_alpha PF05793.12 CAR24090.1 - 0.092 11.3 11.8 0.099 11.2 11.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MCM_bind PF09739.9 CAR24090.1 - 1.5 7.2 3.8 2.1 6.7 3.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PH PF00169.29 CAR24091.1 - 4.2e-05 24.0 0.0 0.00017 22.0 0.0 2.2 1 0 0 1 1 1 1 PH domain PUF PF00806.19 CAR24092.1 - 6.4e-30 101.1 0.7 8.9e-05 22.0 0.0 6.7 7 0 0 7 7 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CAR24092.1 - 2.2e-05 24.2 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S64 PF08192.11 CAR24092.1 - 0.0096 14.5 18.2 0.015 13.8 18.2 1.2 1 0 0 1 1 1 1 Peptidase family S64 Presenilin PF01080.17 CAR24092.1 - 0.013 14.3 26.6 0.023 13.5 26.6 1.3 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 CAR24092.1 - 0.03 12.6 35.6 0.044 12.1 35.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Otopetrin PF03189.13 CAR24092.1 - 0.034 13.0 5.1 0.053 12.3 5.1 1.3 1 0 0 1 1 1 0 Otopetrin EIF4E-T PF10477.9 CAR24092.1 - 0.046 12.6 32.4 0.08 11.8 32.4 1.4 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E NPR3 PF03666.13 CAR24092.1 - 0.063 12.1 19.3 0.11 11.2 19.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 CAR24092.1 - 0.13 12.3 14.2 0.38 10.8 14.2 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CAR24092.1 - 0.18 10.1 5.0 0.28 9.5 5.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CCSAP PF15748.5 CAR24092.1 - 0.32 11.1 27.0 0.71 10.0 27.0 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Folate_carrier PF01770.18 CAR24092.1 - 0.32 9.7 5.2 0.68 8.6 5.2 1.6 1 0 0 1 1 1 0 Reduced folate carrier Membralin PF09746.9 CAR24092.1 - 0.52 9.3 13.8 0.97 8.4 13.8 1.4 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 CAR24092.1 - 0.59 9.1 23.4 0.96 8.4 23.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 CAR24092.1 - 0.62 9.5 23.1 1 8.8 23.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TT_ORF1 PF02956.14 CAR24092.1 - 0.74 8.4 15.3 1.2 7.7 15.3 1.2 1 0 0 1 1 1 0 TT viral orf 1 SART-1 PF03343.13 CAR24092.1 - 0.76 8.3 23.3 1.1 7.8 23.3 1.1 1 0 0 1 1 1 0 SART-1 family CPSF100_C PF13299.6 CAR24092.1 - 1.1 9.5 17.1 2.5 8.3 17.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM76 PF16046.5 CAR24092.1 - 1.1 8.6 22.9 2.3 7.5 22.9 1.5 1 0 0 1 1 1 0 FAM76 protein Lin-8 PF03353.15 CAR24092.1 - 1.1 8.8 29.9 2 7.9 29.9 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Serinc PF03348.15 CAR24092.1 - 1.1 8.1 10.5 0.24 10.3 6.5 1.8 2 0 0 2 2 2 0 Serine incorporator (Serinc) V_ATPase_I PF01496.19 CAR24092.1 - 1.4 6.8 24.2 2.1 6.2 24.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4820 PF16091.5 CAR24092.1 - 1.5 8.2 13.8 3.8 6.8 13.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GREB1 PF15782.5 CAR24092.1 - 1.7 5.7 30.0 2.6 5.1 30.0 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 CAR24092.1 - 2.9 6.1 19.0 4.5 5.4 19.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 CAR24092.1 - 3.3 6.2 30.8 0.0055 15.3 20.3 1.7 2 0 0 2 2 1 0 Macoilin family RR_TM4-6 PF06459.12 CAR24092.1 - 3.5 7.4 23.9 6.1 6.6 23.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 CAR24092.1 - 4.7 6.5 21.1 7.4 5.8 21.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_subunit PF08597.10 CAR24092.1 - 4.9 7.0 18.5 9.4 6.1 18.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Hid1 PF12722.7 CAR24092.1 - 5.4 5.0 23.7 8.4 4.4 23.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.8 CAR24092.1 - 5.7 5.6 20.3 4.5 6.0 18.6 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 CAR24092.1 - 7.1 5.8 17.9 23 4.1 17.9 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 CAR24092.1 - 8.9 5.0 20.1 15 4.3 20.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1764 PF08576.10 CAR24092.1 - 9.6 7.2 17.1 31 5.5 17.1 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) F-box-like PF12937.7 CAR24093.1 - 8.4e-08 32.0 0.4 2.2e-07 30.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CAR24093.1 - 7.1e-06 26.3 8.5 2.9 8.5 0.0 6.9 4 3 2 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 CAR24093.1 - 0.00028 20.7 0.3 0.00088 19.1 0.3 2.0 1 0 0 1 1 1 1 F-box domain BIR PF00653.21 CAR24094.1 - 2.1e-16 60.3 8.0 1.5e-11 44.7 0.8 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain AT_hook PF02178.19 CAR24094.1 - 0.0012 18.5 38.0 0.041 13.8 1.3 4.6 4 0 0 4 4 4 4 AT hook motif eIF-5_eIF-2B PF01873.17 CAR24095.1 - 1.6e-38 131.2 0.0 3e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CAR24095.1 - 3.4e-24 84.8 0.9 3.9e-22 78.2 0.0 2.9 2 1 0 2 2 2 2 eIF4-gamma/eIF5/eIF2-epsilon TPR_1 PF00515.28 CAR24096.1 - 0.00058 19.6 1.6 0.001 18.8 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR24096.1 - 0.0012 18.9 1.9 0.0094 16.1 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR24096.1 - 0.0049 16.9 0.4 0.0049 16.9 0.4 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAR24096.1 - 0.01 16.6 1.9 0.033 15.0 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR24096.1 - 0.021 15.2 0.1 2 9.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAR24096.1 - 0.072 13.6 1.3 0.44 11.1 0.7 2.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR24096.1 - 0.079 13.6 2.1 0.81 10.4 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 CAR24096.1 - 0.1 12.8 0.3 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4297 PF14130.6 CAR24096.1 - 0.19 11.9 3.3 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4297) TIP41 PF04176.13 CAR24097.1 - 3.3e-68 228.5 1.2 5e-68 227.9 1.2 1.3 1 0 0 1 1 1 1 TIP41-like family Evr1_Alr PF04777.13 CAR24098.1 - 3.9e-23 81.8 0.2 9e-23 80.6 0.2 1.6 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 CAR24098.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 APOBEC1 XOO_2897-deam PF14440.6 CAR24098.1 - 0.17 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase G-gamma PF00631.22 CAR24099.1 - 3e-23 81.6 0.0 3.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain Tmemb_14 PF03647.13 CAR24100.1 - 7.1e-23 81.2 7.1 7.9e-23 81.0 7.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 CAR24100.1 - 0.0049 17.2 1.3 0.0085 16.4 1.3 1.4 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Gram_pos_anchor PF00746.21 CAR24100.1 - 1.6 8.7 0.1 1.6 8.7 0.1 3.4 4 0 0 4 4 4 0 LPXTG cell wall anchor motif PCI PF01399.27 CAR24101.1 - 2.1e-12 47.5 0.2 7.4e-12 45.7 0.2 2.0 1 0 0 1 1 1 1 PCI domain DUF1481 PF07356.12 CAR24101.1 - 0.032 14.0 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) CC2-LZ PF16516.5 CAR24102.1 - 0.026 14.9 0.4 0.026 14.9 0.4 1.9 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator CCDC32 PF14989.6 CAR24102.1 - 0.034 14.2 4.3 0.049 13.6 0.4 2.3 1 1 1 2 2 2 0 Coiled-coil domain containing 32 DUF5623 PF18536.1 CAR24102.1 - 0.068 13.5 0.5 1.9 8.8 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5623) zf-C4pol PF14260.6 CAR24102.1 - 0.16 12.5 0.2 0.16 12.5 0.2 1.8 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta LMBR1 PF04791.16 CAR24102.1 - 0.32 9.9 2.5 0.32 9.9 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Leu_zip PF15294.6 CAR24102.1 - 0.86 9.1 7.9 0.74 9.3 2.3 2.3 1 1 1 2 2 2 0 Leucine zipper Muted PF14942.6 CAR24102.1 - 2.4 8.5 7.7 0.31 11.4 1.5 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein V-ATPase_H_N PF03224.14 CAR24103.1 - 1.1e-66 225.3 9.8 2.2e-66 224.3 6.9 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CAR24103.1 - 5.3e-41 139.4 2.4 6.6e-41 139.1 0.4 2.2 2 0 0 2 2 2 1 V-ATPase subunit H Gln-synt_C PF00120.24 CAR24104.1 - 6.2e-19 68.2 0.0 2.6e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CAR24104.1 - 5.2e-14 51.7 0.0 9.5e-14 50.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Hydrolase_6 PF13344.6 CAR24105.1 - 4.2e-23 81.4 0.0 9.6e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR24105.1 - 4.6e-14 52.2 0.0 1.7e-13 50.4 0.0 2.1 2 1 0 2 2 2 1 HAD-hyrolase-like Aha1_N PF09229.11 CAR24106.1 - 1.1e-38 132.5 1.4 2.9e-38 131.2 0.1 2.3 3 0 0 3 3 3 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CAR24106.1 - 1.1e-13 51.5 0.1 1.8e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF4670 PF15709.5 CAR24106.1 - 0.24 10.7 0.2 0.33 10.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) Fungal_trans_2 PF11951.8 CAR24107.1 - 4.9e-13 48.7 1.0 4.9e-13 48.7 1.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR24107.1 - 6e-09 35.9 12.6 9.7e-09 35.2 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1840 PF08895.11 CAR24107.1 - 0.76 10.1 12.4 6.7 7.1 5.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Cpn60_TCP1 PF00118.24 CAR24108.1 - 1.5e-152 508.7 14.0 1.7e-152 508.5 14.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.18 CAR24108.1 - 0.066 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Telomere recombination PQ-loop PF04193.14 CAR24109.1 - 1.2e-22 79.5 9.1 3.8e-19 68.2 1.6 2.5 2 0 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.6 CAR24109.1 - 5 6.6 18.2 0.33 10.5 5.2 2.3 1 1 0 2 2 2 0 ABC-2 family transporter protein Ras PF00071.22 CAR24110.1 - 1.8e-51 173.9 0.0 2.1e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24110.1 - 1.7e-18 67.0 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24110.1 - 2.7e-07 30.2 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family W2 PF02020.18 CAR24111.1 - 2.9e-14 52.9 6.6 2.9e-14 52.9 6.6 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CAR24111.1 - 1.1e-11 44.0 14.5 5.7e-05 22.7 2.8 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CAR24111.1 - 1.9e-09 37.5 0.0 3.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 CAR24111.1 - 5.6e-05 22.3 0.5 0.00015 20.8 0.5 1.6 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CAR24111.1 - 0.00017 19.9 2.0 0.0003 19.1 0.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CAR24111.1 - 0.00099 18.8 16.2 0.2 11.5 4.0 3.9 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 CAR24111.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain CYSTM PF12734.7 CAR24112.1 - 5.4e-10 39.4 60.7 4.1e-05 23.8 46.8 3.7 1 1 1 2 2 2 2 Cysteine-rich TM module stress tolerance Pro-rich PF15240.6 CAR24112.1 - 0.026 14.8 26.5 0.031 14.6 26.5 1.1 1 0 0 1 1 1 0 Proline-rich Pex14_N PF04695.13 CAR24112.1 - 2 9.0 6.0 2.2 8.9 6.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIP5K PF01504.18 CAR24113.1 - 2.7e-95 318.7 1.7 4.4e-95 318.0 1.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase E1-E2_ATPase PF00122.20 CAR24114.1 - 2.2e-34 118.5 11.9 2.4e-29 102.1 0.0 3.9 3 2 2 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CAR24114.1 - 2.4e-26 92.6 2.0 2.4e-26 92.6 2.0 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CAR24114.1 - 1.6e-21 76.1 0.0 3.3e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR24114.1 - 7.4e-21 75.4 0.1 1.5e-16 61.3 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAR24114.1 - 4.2e-12 45.6 0.0 1.3e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR24114.1 - 0.00056 19.7 0.6 0.0061 16.3 1.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Aminotran_5 PF00266.19 CAR24115.1 - 1.4e-12 47.3 0.0 5.6e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Zn_clus PF00172.18 CAR24116.1 - 5.9e-09 35.9 8.4 1e-08 35.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1_DNA_bind PF10373.9 CAR24117.1 - 1.2e-59 202.1 0.6 1.2e-59 202.1 0.6 2.0 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CAR24117.1 - 3.3e-21 76.4 1.7 3.3e-21 76.4 1.7 2.2 3 0 0 3 3 3 1 Telomerase activating protein Est1 Topoisom_bac PF01131.20 CAR24118.1 - 3.6e-105 352.4 0.0 4.4e-105 352.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CAR24118.1 - 2.6e-19 69.3 0.0 6.7e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HrpB1_HrpK PF09613.10 CAR24118.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Cation_efflux PF01545.21 CAR24119.1 - 4.4e-41 140.8 16.4 4.4e-41 140.8 16.4 2.7 2 1 0 2 2 2 1 Cation efflux family UPF0242 PF06785.11 CAR24119.1 - 0.074 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Transp_cyt_pur PF02133.15 CAR24120.1 - 1.7e-74 251.2 38.6 2.4e-74 250.7 38.6 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Coq4 PF05019.13 CAR24121.1 - 3.7e-94 314.2 0.0 4.6e-94 313.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Rogdi_lz PF10259.9 CAR24122.1 - 1.8e-59 201.4 0.9 2.1e-59 201.2 0.9 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein YfkD PF14167.6 CAR24122.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 YfkD-like protein DASH_Spc19 PF08287.11 CAR24123.1 - 1.9e-34 118.9 12.5 2.2e-34 118.6 12.5 1.1 1 0 0 1 1 1 1 Spc19 DUF871 PF05913.11 CAR24123.1 - 0.024 13.9 0.3 0.03 13.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) RNA_pol_Rpb5_C PF01191.19 CAR24123.1 - 0.029 14.2 1.3 0.31 10.9 0.1 2.5 2 1 1 3 3 3 0 RNA polymerase Rpb5, C-terminal domain DUF155 PF02582.14 CAR24123.1 - 0.063 13.4 2.1 0.08 13.0 0.2 2.0 2 1 1 3 3 3 0 Uncharacterised ACR, YagE family COG1723 APG6_N PF17675.1 CAR24123.1 - 0.25 11.9 10.7 0.25 11.8 6.5 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region FHA PF00498.26 CAR24124.1 - 4.4e-18 65.4 0.9 2.9e-17 62.8 0.4 2.5 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CAR24124.1 - 2.1e-06 27.9 1.2 5.2e-06 26.7 0.0 2.3 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain HAUS6_N PF14661.6 CAR24124.1 - 0.12 11.9 8.1 0.24 11.0 8.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4200 PF13863.6 CAR24124.1 - 0.15 12.5 19.7 0.48 10.8 17.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BPL_LplA_LipB PF03099.19 CAR24125.1 - 3.3e-19 69.1 0.0 5.4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family U71 PF17474.2 CAR24125.1 - 0.038 13.9 0.1 0.083 12.8 0.1 1.5 1 0 0 1 1 1 0 Tegument protein UL11 homolog SET PF00856.28 CAR24126.1 - 0.0011 19.4 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 SET domain PSD4 PF07631.11 CAR24126.1 - 0.15 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) ApbA PF02558.16 CAR24127.1 - 7.3e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CAR24127.1 - 0.00019 21.7 0.0 0.0011 19.2 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CoaE PF01121.20 CAR24128.1 - 8.8e-59 198.2 0.0 1e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CAR24128.1 - 8.6e-05 23.1 0.1 0.00039 21.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 CAR24128.1 - 0.0003 21.0 0.0 0.0018 18.4 0.0 2.0 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.6 CAR24128.1 - 0.00061 20.0 0.0 0.0053 16.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAR24128.1 - 0.0065 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 CAR24128.1 - 0.0099 16.0 0.6 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase-like family PRK PF00485.18 CAR24128.1 - 0.011 15.4 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 CAR24128.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 CAR24128.1 - 0.15 11.4 0.1 0.31 10.4 0.0 1.5 2 0 0 2 2 2 0 Isopentenyl transferase DEAD PF00270.29 CAR24130.1 - 1.6e-41 142.0 0.1 2.7e-41 141.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR24130.1 - 5.5e-20 71.8 0.0 1.1e-18 67.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR24130.1 - 2.1e-08 34.4 0.1 3.8e-08 33.5 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CAR24130.1 - 0.096 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PI3Ka PF00613.20 CAR24131.1 - 4.7e-68 228.2 0.8 7.6e-68 227.6 0.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CAR24131.1 - 1.3e-50 172.5 0.1 8.8e-48 163.3 0.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CAR24131.1 - 1.2e-22 80.4 1.0 2.5e-22 79.3 0.1 2.1 3 0 0 3 3 3 1 Phosphoinositide 3-kinase C2 RSN1_7TM PF02714.15 CAR24132.1 - 4.1e-79 265.7 24.2 7.3e-79 264.9 24.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR24132.1 - 1e-37 129.3 0.3 1e-37 129.3 0.3 2.4 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CAR24132.1 - 3.7e-31 108.7 0.0 6.3e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Neurensin PF14927.6 CAR24132.1 - 2.1 8.1 9.0 1.8 8.3 0.3 3.6 3 1 0 3 3 3 0 Neurensin YMF19 PF02326.15 CAR24132.1 - 3.8 8.4 8.5 19 6.1 0.6 3.8 2 1 1 3 3 3 0 Plant ATP synthase F0 Arv1 PF04161.13 CAR24133.1 - 2e-62 211.1 13.9 2e-62 211.1 13.9 1.4 2 0 0 2 2 2 1 Arv1-like family zf-CCCH_4 PF18044.1 CAR24134.1 - 2.5e-07 30.3 2.6 4.9e-07 29.4 2.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAR24134.1 - 5.8e-07 29.4 8.4 1.2e-06 28.4 8.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CAR24134.1 - 1.1e-06 28.3 3.2 2.1e-06 27.5 3.2 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAR24134.1 - 0.0053 17.4 1.1 0.011 16.4 1.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_3 PF15663.5 CAR24134.1 - 0.22 11.8 0.8 0.53 10.5 0.8 1.6 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CAR24134.1 - 0.24 11.9 5.6 0.45 11.1 5.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger ATP_bind_1 PF03029.17 CAR24135.1 - 5.2e-86 288.3 0.0 6e-86 288.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CAR24135.1 - 0.00069 19.5 0.0 0.013 15.3 0.0 2.5 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 CAR24135.1 - 0.00071 18.6 0.0 0.0014 17.7 0.0 1.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CAR24135.1 - 0.0035 17.4 0.0 0.016 15.3 0.0 2.3 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR24135.1 - 0.0035 16.9 0.0 0.43 10.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR24135.1 - 0.0042 17.0 0.6 0.059 13.3 0.1 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_10 PF12846.7 CAR24135.1 - 0.0044 16.0 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain KAP_NTPase PF07693.14 CAR24135.1 - 0.0061 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain DUF87 PF01935.17 CAR24135.1 - 0.0074 16.4 0.0 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain ABC_tran PF00005.27 CAR24135.1 - 0.0075 16.8 0.0 0.024 15.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 CAR24135.1 - 0.0077 16.8 0.0 0.039 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAR24135.1 - 0.0077 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR24135.1 - 0.0081 16.5 0.0 0.032 14.6 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_7 PF12775.7 CAR24135.1 - 0.021 14.3 0.0 0.081 12.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 CAR24135.1 - 0.025 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CAR24135.1 - 0.031 14.7 0.0 0.071 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 CAR24135.1 - 0.034 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CAR24135.1 - 0.039 14.3 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAR24135.1 - 0.039 14.2 0.0 0.082 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAR24135.1 - 0.044 13.5 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 CAR24135.1 - 0.054 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CAR24135.1 - 0.055 13.4 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 1 0 NACHT domain Thymidylate_kin PF02223.17 CAR24135.1 - 0.058 13.1 0.0 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.19 CAR24135.1 - 0.061 12.9 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CAR24135.1 - 0.076 12.2 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_31 PF13614.6 CAR24135.1 - 0.08 12.9 0.0 2.8 7.8 0.0 2.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 CAR24135.1 - 0.1 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_14 PF13173.6 CAR24135.1 - 0.11 12.6 0.0 0.39 10.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 CAR24135.1 - 0.11 11.7 0.4 2.3 7.3 0.0 2.3 2 1 0 2 2 2 0 G-protein alpha subunit AAA_17 PF13207.6 CAR24135.1 - 0.11 12.9 0.0 0.65 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 CAR24135.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.6 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 CAR24135.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Dynamin family CbiA PF01656.23 CAR24135.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 CAR24135.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Fer4_NifH PF00142.18 CAR24135.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ATPase_2 PF01637.18 CAR24135.1 - 0.15 12.0 0.0 1.3 8.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CAR24135.1 - 0.16 11.7 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ADK PF00406.22 CAR24135.1 - 0.19 11.8 0.1 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase SIR2 PF02146.17 CAR24136.1 - 1.8e-28 99.6 0.0 2.9e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family zf-RRPl_C4 PF17026.5 CAR24136.1 - 0.046 13.8 0.8 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type TIP49 PF06068.13 CAR24137.1 - 6.6e-168 558.4 0.4 1e-167 557.8 0.4 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CAR24137.1 - 3.9e-24 84.5 0.1 1e-23 83.2 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CAR24137.1 - 1.5e-08 35.1 0.2 5.8e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAR24137.1 - 4e-07 29.9 0.2 9.8e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR24137.1 - 0.00096 19.4 0.0 0.002 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR24137.1 - 0.0033 17.8 0.9 2.9 8.2 0.3 2.5 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.15 CAR24137.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_14 PF13173.6 CAR24137.1 - 0.015 15.3 0.1 1.3 9.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CAR24137.1 - 0.023 14.1 0.1 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CAR24137.1 - 0.023 14.0 0.1 0.072 12.4 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 CAR24137.1 - 0.041 13.9 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.12 CAR24137.1 - 0.044 13.6 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 CAR24137.1 - 0.052 13.9 0.2 0.48 10.8 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.26 CAR24137.1 - 0.072 12.8 0.0 7.4 6.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Sec1 PF00995.23 CAR24138.1 - 6.8e-118 395.4 7.3 7.8e-118 395.2 7.3 1.0 1 0 0 1 1 1 1 Sec1 family DUF2780 PF11075.8 CAR24138.1 - 0.038 14.1 0.8 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) KaiA PF07688.12 CAR24138.1 - 0.13 12.4 1.8 0.89 9.7 0.1 3.0 4 0 0 4 4 4 0 KaiA C-terminal domain RAC_head PF16717.5 CAR24138.1 - 0.48 11.4 2.3 16 6.6 0.1 3.2 3 0 0 3 3 3 0 Ribosome-associated complex head domain Cpn60_TCP1 PF00118.24 CAR24139.1 - 1.8e-160 534.8 2.3 2.1e-160 534.6 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.24 CAR24140.1 - 2.7e-51 174.2 0.1 3.3e-51 173.9 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CAR24140.1 - 3.3e-14 52.9 11.5 3.3e-14 52.9 11.5 1.7 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding dCMP_cyt_deam_1 PF00383.23 CAR24141.1 - 6.7e-17 61.2 0.9 8e-17 61.0 0.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CAR24141.1 - 3.2e-12 46.8 1.0 1.1e-09 38.5 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CAR24141.1 - 0.021 14.4 2.5 0.69 9.5 0.3 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases NOA36 PF06524.12 CAR24142.1 - 0.66 9.3 5.5 1.3 8.3 5.5 1.3 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.13 CAR24142.1 - 5.9 6.9 8.7 1.2 9.2 3.6 2.1 2 0 0 2 2 2 0 YL1 nuclear protein DHHC PF01529.20 CAR24143.1 - 1.7e-32 112.3 17.8 1.7e-32 112.3 17.8 2.3 2 2 0 2 2 2 1 DHHC palmitoyltransferase CitMHS PF03600.16 CAR24143.1 - 0.22 10.7 1.8 0.26 10.5 0.1 1.8 2 0 0 2 2 2 0 Citrate transporter ABC2_membrane_2 PF12679.7 CAR24143.1 - 5.6 6.2 5.9 0.9 8.8 0.1 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein PRELI PF04707.14 CAR24144.1 - 4.1e-56 189.1 0.4 5.6e-56 188.7 0.4 1.2 1 0 0 1 1 1 1 PRELI-like family CxC3 PF18804.1 CAR24144.1 - 0.059 13.2 0.2 0.092 12.6 0.2 1.3 1 0 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases ubiquitin PF00240.23 CAR24146.1 - 3.7e-34 116.3 0.6 7.4e-34 115.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CAR24146.1 - 9.1e-25 86.6 3.4 9.1e-25 86.6 3.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CAR24146.1 - 4.6e-16 58.4 0.7 4.6e-16 58.4 0.7 1.9 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR24146.1 - 2.6e-05 24.6 0.1 0.00012 22.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR24146.1 - 0.001 19.2 0.6 0.0027 17.8 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CAR24146.1 - 0.0032 17.8 0.6 0.0075 16.6 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain Zn_ribbon_SprT PF17283.2 CAR24146.1 - 0.0048 16.8 2.0 0.0087 16.0 2.0 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain TBK1_ULD PF18396.1 CAR24146.1 - 0.0052 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CAR24146.1 - 0.012 16.1 0.4 0.016 15.7 0.4 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CAR24146.1 - 0.017 15.1 1.0 5.6 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain DZR PF12773.7 CAR24146.1 - 0.032 14.3 1.3 0.071 13.2 1.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon Nudix_N_2 PF14803.6 CAR24146.1 - 1 9.4 5.5 6.3 6.8 5.2 2.3 1 1 1 2 2 2 0 Nudix N-terminal zinc_ribbon_2 PF13240.6 CAR24146.1 - 6 6.7 7.9 4.9 7.0 1.3 2.9 3 0 0 3 3 3 0 zinc-ribbon domain Phosducin PF02114.16 CAR24147.1 - 1.5e-11 43.7 0.3 1.9e-11 43.4 0.3 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CAR24147.1 - 3.9e-06 26.8 0.1 6.2e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Plk4_PB2 PF18409.1 CAR24147.1 - 0.046 14.4 0.6 0.071 13.8 0.6 1.3 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 Sec10 PF07393.11 CAR24148.1 - 1.4e-188 628.7 20.3 1.7e-188 628.4 20.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 PEPcase_2 PF14010.6 CAR24148.1 - 0.001 17.7 0.7 0.0022 16.6 0.7 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase COG2 PF06148.11 CAR24148.1 - 0.14 12.3 5.2 0.082 13.0 0.3 3.2 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Metallophos PF00149.28 CAR24149.1 - 4.6e-11 43.6 1.0 7.9e-11 42.8 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UreD PF01774.17 CAR24149.1 - 0.14 12.0 0.0 0.49 10.3 0.0 1.9 1 1 0 1 1 1 0 UreD urease accessory protein EMC3_TMCO1 PF01956.16 CAR24149.1 - 4.9 6.8 7.3 4.3 7.0 0.4 2.3 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SAS4 PF15460.6 CAR24150.1 - 2.1e-29 101.5 3.3 4.8e-29 100.4 3.3 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DUF935 PF06074.12 CAR24150.1 - 0.0033 16.2 0.0 0.0033 16.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF935) ORC6 PF05460.13 CAR24150.1 - 1.2 8.3 10.5 2.1 7.6 4.2 2.2 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Nipped-B_C PF12830.7 CAR24151.1 - 2.3e-27 96.2 0.2 2.3e-27 96.2 0.2 3.5 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CAR24151.1 - 3.8e-15 55.9 0.4 3.5e-12 46.4 1.6 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion SYCP2_ARLD PF18581.1 CAR24151.1 - 0.018 15.0 1.7 0.48 10.4 0.2 3.0 2 0 0 2 2 2 0 Synaptonemal complex 2 armadillo-repeat-like domain TBCC_N PF16752.5 CAR24151.1 - 1.1 9.7 4.8 1.7 9.1 0.2 3.2 3 1 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain PseudoU_synth_2 PF00849.22 CAR24152.1 - 3.9e-21 75.8 0.4 4e-19 69.2 0.4 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase PXA PF02194.15 CAR24153.1 - 4.6e-16 59.3 0.5 1.5e-14 54.4 0.5 2.6 1 1 0 1 1 1 1 PXA domain Nexin_C PF08628.12 CAR24153.1 - 0.002 18.7 0.0 0.093 13.3 0.0 2.3 2 0 0 2 2 2 1 Sorting nexin C terminal CybS PF05328.12 CAR24155.1 - 1.4e-51 173.6 0.0 1.8e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Sdh_cyt PF01127.22 CAR24155.1 - 0.0041 17.1 0.3 1.3 9.0 0.0 2.2 1 1 1 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Peptidase_M16 PF00675.20 CAR24156.1 - 6.6e-51 172.2 0.0 1.2e-50 171.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAR24156.1 - 5e-36 124.4 0.0 4.7e-34 118.0 0.0 2.5 3 0 0 3 3 3 2 Peptidase M16 inactive domain Ada3 PF10198.9 CAR24157.1 - 4.7e-44 149.7 5.3 4.7e-44 149.7 5.3 1.9 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 CCDC-167 PF15188.6 CAR24157.1 - 0.4 11.1 0.0 0.4 11.1 0.0 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 MRP-S28 PF10213.9 CAR24158.1 - 7.7e-54 181.5 2.5 1.7e-53 180.4 2.5 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein HMG_box PF00505.19 CAR24159.1 - 6.2e-10 39.4 2.4 6.2e-10 39.4 2.4 2.4 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR24159.1 - 2.1e-07 31.4 1.7 2.1e-07 31.4 1.7 1.9 2 0 0 2 2 2 1 HMG-box domain DUF3086 PF11285.8 CAR24159.1 - 0.031 13.4 0.3 0.031 13.4 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) MscS_porin PF12795.7 CAR24159.1 - 0.093 12.3 4.6 0.18 11.3 0.8 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain HAD_2 PF13419.6 CAR24159.1 - 0.14 12.3 1.4 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.16 CAR24160.1 - 4.3e-33 114.7 27.4 9.7e-33 113.5 27.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CAR24160.1 - 3.7e-07 29.8 3.3 8e-07 28.7 3.3 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Zip PF02535.22 CAR24161.1 - 3.9e-69 233.4 11.3 4.5e-69 233.2 11.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter IPK PF03770.16 CAR24162.1 - 3.1e-55 187.1 0.1 4.2e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase GTP_EFTU PF00009.27 CAR24163.1 - 1.4e-45 155.3 0.1 6e-45 153.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAR24163.1 - 6.1e-35 119.9 0.6 1.6e-34 118.6 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAR24163.1 - 2.3e-06 27.9 0.3 6.9e-06 26.4 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR24163.1 - 0.00078 19.5 0.1 0.0044 17.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Hamartin PF04388.12 CAR24163.1 - 0.011 14.5 5.9 0.015 14.0 5.9 1.1 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 CAR24163.1 - 0.17 11.2 22.6 0.26 10.6 22.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 eIF-3c_N PF05470.12 CAR24163.1 - 4.8 5.4 9.6 7.9 4.7 9.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HSP20 PF00011.21 CAR24164.1 - 3.4e-10 40.0 0.4 7.3e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAR24164.1 - 9e-05 22.0 0.1 0.00051 19.5 0.0 2.2 2 1 0 2 2 2 1 HSP20-like domain found in ArsA YqfQ PF14181.6 CAR24164.1 - 0.085 13.0 3.4 0.2 11.8 3.4 1.6 1 1 0 1 1 1 0 YqfQ-like protein GTP_CH_N PF12471.8 CAR24165.1 - 2e-82 275.7 0.0 2.9e-82 275.1 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 CAR24165.1 - 8.6e-18 64.5 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II CBP_BcsO PF17037.5 CAR24165.1 - 0.0096 16.1 0.1 0.016 15.3 0.1 1.2 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsO Sec7 PF01369.20 CAR24166.1 - 6.8e-69 231.2 0.5 2e-68 229.7 0.5 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CAR24166.1 - 4.8e-45 153.3 2.3 4.8e-45 153.3 2.3 4.2 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CAR24166.1 - 1.6e-31 108.0 7.1 3.9e-28 97.1 0.1 6.0 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 CAR24166.1 - 2.7e-19 69.5 8.5 9.7e-19 67.7 2.4 3.8 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Chorismate_synt PF01264.21 CAR24167.1 - 7.5e-140 465.3 0.0 8.6e-140 465.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase SH3_2 PF07653.17 CAR24168.1 - 2.3e-07 30.4 0.1 4.9e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAR24168.1 - 2.6e-05 23.7 0.6 5.5e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CAR24168.1 - 0.00047 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.19 CAR24168.1 - 0.0016 18.9 0.0 0.01 16.2 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily Nup84_Nup100 PF04121.13 CAR24169.1 - 2.8e-165 551.4 7.9 3.2e-165 551.2 7.9 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Ribosomal_L6 PF00347.23 CAR24170.1 - 2.6e-32 111.3 12.2 1e-16 61.4 5.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 SLS PF14611.6 CAR24170.1 - 0.03 14.1 0.3 0.044 13.6 0.2 1.5 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Iwr1 PF08574.10 CAR24171.1 - 2.2e-13 51.0 16.2 2.2e-13 51.0 16.2 2.3 2 1 0 2 2 2 1 Transcription factor Iwr1 PX PF00787.24 CAR24172.1 - 7.8e-24 83.8 0.1 3e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 PX domain DASH_Dad4 PF08650.10 CAR24172.1 - 0.094 12.7 1.3 2.9 7.9 0.0 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad4 EF-G-binding_N PF07299.11 CAR24172.1 - 0.13 12.8 5.0 6.9 7.3 0.1 3.6 3 1 1 4 4 4 0 Elongation factor G-binding protein, N-terminal GAS PF13851.6 CAR24172.1 - 0.32 10.3 14.1 1.3 8.4 4.2 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Retrotrans_gag PF03732.17 CAR24172.1 - 0.47 10.7 2.4 0.57 10.5 0.2 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF5082 PF16888.5 CAR24172.1 - 0.69 10.2 8.9 0.5 10.7 3.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) ApoLp-III PF07464.11 CAR24172.1 - 0.79 9.8 7.1 1.1 9.3 0.7 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ABC_tran_CTD PF16326.5 CAR24172.1 - 0.81 10.0 7.4 9 6.6 1.6 3.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain CHDCT2 PF08074.11 CAR24172.1 - 0.95 9.6 6.4 1 9.5 3.3 2.6 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DUF4363 PF14276.6 CAR24172.1 - 1.3 9.2 7.5 1.2 9.3 0.0 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF4363) FlxA PF14282.6 CAR24172.1 - 2.8 8.0 0.0 2.8 8.0 0.0 4.2 5 0 0 5 5 5 0 FlxA-like protein SpoU_methylase PF00588.19 CAR24173.1 - 4.1e-25 88.6 0.0 1.1e-24 87.3 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family RNase_PH PF01138.21 CAR24174.1 - 1.4e-11 45.0 0.0 2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAR24174.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 MOZART1 PF12554.8 CAR24174.1 - 0.049 13.4 0.2 5.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated EMP24_GP25L PF01105.24 CAR24175.1 - 7.6e-09 35.8 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cortex-I_coil PF09304.10 CAR24176.1 - 0.00052 20.2 2.4 0.00056 20.1 1.2 1.6 1 1 0 2 2 2 1 Cortexillin I, coiled coil RINT1_TIP1 PF04437.13 CAR24177.1 - 4.8e-65 220.4 25.0 7.9e-65 219.6 25.0 1.4 1 0 0 1 1 1 1 RINT-1 / TIP-1 family MnmE_helical PF12631.7 CAR24177.1 - 0.67 10.1 6.1 0.25 11.5 2.0 2.2 2 1 0 2 2 2 0 MnmE helical domain DUF676 PF05057.14 CAR24178.1 - 2.5e-58 197.1 0.0 4e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 CAR24178.1 - 0.0066 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 CAR24178.1 - 0.0073 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 CAR24178.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 CAR24178.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 CAR24178.1 - 0.032 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PCRF PF03462.18 CAR24179.1 - 1.9e-54 184.5 0.2 1e-53 182.1 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CAR24179.1 - 1.2e-37 128.4 3.5 2.7e-37 127.2 3.5 1.6 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 CAR24179.1 - 0.017 14.9 0.3 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 MIR domain ARA70 PF12489.8 CAR24179.1 - 0.47 10.6 4.3 0.16 12.2 1.3 1.8 2 0 0 2 2 2 0 Nuclear coactivator FliT PF05400.13 CAR24179.1 - 6.9 7.6 8.8 2.9 8.8 2.5 3.1 2 1 0 2 2 2 0 Flagellar protein FliT Pkinase PF00069.25 CAR24180.1 - 3.1e-69 233.3 0.0 3.5e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24180.1 - 6.4e-29 101.0 0.0 8.2e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR24180.1 - 0.00033 20.0 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR24180.1 - 0.0065 16.4 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR24180.1 - 0.069 11.9 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DAO PF01266.24 CAR24181.1 - 2.2e-55 188.6 0.0 2.5e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR24181.1 - 5.9e-07 29.6 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAR24181.1 - 5e-05 22.6 0.1 0.002 17.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 CAR24181.1 - 0.00014 22.1 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 CAR24181.1 - 0.00033 20.0 0.0 0.0072 15.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR24181.1 - 0.0011 19.4 0.0 0.0064 17.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAR24181.1 - 0.0015 17.8 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CAR24181.1 - 0.0031 16.3 0.0 0.023 13.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CAR24181.1 - 0.0073 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CAR24181.1 - 0.0095 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GMC_oxred_N PF00732.19 CAR24181.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 GMC oxidoreductase NAD_binding_9 PF13454.6 CAR24181.1 - 0.089 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 CAR24181.1 - 0.16 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TPR_8 PF13181.6 CAR24182.1 - 1.3e-06 28.2 2.3 0.1 12.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR24182.1 - 7.1e-05 22.6 1.7 0.22 11.7 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAR24182.1 - 0.00022 21.8 0.0 0.25 12.2 0.0 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR24182.1 - 0.00023 21.0 0.1 0.77 9.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24182.1 - 0.0014 18.9 0.3 0.026 14.8 0.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR24182.1 - 0.0015 18.2 1.7 0.42 10.5 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR24182.1 - 0.23 12.2 0.8 0.74 10.5 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR24182.1 - 0.45 10.8 4.5 0.87 9.9 0.1 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 CAR24182.1 - 8 7.3 8.4 51 4.7 0.0 4.7 4 1 0 4 4 4 0 Sel1 repeat Glyco_transf_22 PF03901.17 CAR24183.1 - 3.4e-96 323.0 31.9 4.1e-96 322.8 31.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family AbiH PF14253.6 CAR24183.1 - 0.026 14.4 0.3 0.054 13.4 0.3 1.5 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH HECT PF00632.25 CAR24184.1 - 2.5e-82 276.8 0.4 5.5e-82 275.7 0.4 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CAR24185.1 - 7.5e-11 42.2 0.2 1.3e-10 41.4 0.2 1.5 1 0 0 1 1 1 1 SPRY domain Homeodomain PF00046.29 CAR24186.1 - 1.6e-19 69.5 4.0 2.8e-19 68.7 4.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CAR24186.1 - 0.0049 16.7 1.6 0.0086 16.0 0.8 1.8 2 0 0 2 2 2 1 Homeobox KN domain Aldedh PF00171.22 CAR24187.1 - 3.5e-172 573.1 0.0 4e-172 572.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CAR24188.1 - 6.2e-170 565.7 0.8 7.1e-170 565.5 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3813 PF12758.7 CAR24188.1 - 0.14 12.5 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Cep3 PF16846.5 CAR24189.1 - 1.5e-202 673.7 1.9 1.7e-202 673.5 1.9 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 CAR24189.1 - 5.4e-06 26.4 10.4 1.2e-05 25.4 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mlh1_C PF16413.5 CAR24190.1 - 1.4e-80 270.6 0.0 2.5e-80 269.7 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CAR24190.1 - 5e-30 103.6 0.0 1e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CAR24190.1 - 6.8e-12 45.4 0.1 1.6e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAR24190.1 - 5.4e-06 26.9 0.0 1.3e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nse4_C PF08743.10 CAR24191.1 - 8.8e-31 106.0 1.8 1.5e-30 105.3 0.0 2.3 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CAR24191.1 - 6e-09 35.9 1.1 1.7e-08 34.4 1.1 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Peptidase_M22 PF00814.25 CAR24192.1 - 2.3e-71 240.7 0.0 2.8e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Mito_carr PF00153.27 CAR24193.1 - 5e-63 209.1 0.8 7.1e-23 80.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LNS2 PF08235.13 CAR24194.1 - 6.6e-94 313.6 0.0 8.8e-94 313.2 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CAR24194.1 - 2.9e-42 142.8 0.0 5.1e-42 142.0 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region WRNPLPNID PF15017.6 CAR24194.1 - 0.024 15.5 0.6 0.024 15.5 0.6 3.4 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box Hydrolase_6 PF13344.6 CAR24194.1 - 0.084 13.0 0.0 0.3 11.2 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LisH PF08513.11 CAR24195.1 - 0.0016 18.4 1.2 0.0045 16.9 1.2 1.8 1 0 0 1 1 1 1 LisH Vezatin PF12632.7 CAR24196.1 - 1.5e-13 50.8 4.5 4.6e-13 49.2 4.5 1.8 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF2710 PF10921.8 CAR24196.1 - 0.12 12.7 0.1 0.45 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) UDPGP PF01704.18 CAR24197.1 - 1.1e-49 169.2 0.0 1.4e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CAR24197.1 - 0.0093 16.3 0.0 0.018 15.4 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain PhoLip_ATPase_C PF16212.5 CAR24198.1 - 1.4e-70 237.9 20.2 1.4e-70 237.9 20.2 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR24198.1 - 4.9e-23 80.6 0.1 4.9e-23 80.6 0.1 3.1 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CAR24198.1 - 1.7e-14 54.7 0.0 1.8e-07 31.7 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR24198.1 - 1e-11 44.8 0.0 1.3e-10 41.2 0.0 2.7 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CAR24198.1 - 7e-11 42.0 0.0 2e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAR24198.1 - 0.0029 17.4 2.5 0.018 14.8 0.1 3.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.31 CAR24199.1 - 3e-26 91.3 1.7 4.7e-26 90.7 1.7 1.3 1 0 0 1 1 1 1 DnaJ domain LprI PF07007.12 CAR24199.1 - 0.048 14.3 0.0 0.084 13.5 0.0 1.4 1 0 0 1 1 1 0 Lysozyme inhibitor LprI RPT PF13446.6 CAR24199.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF5312 PF17239.2 CAR24199.1 - 0.094 11.0 0.2 0.12 10.7 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5312) UBA_2 PF08587.11 CAR24199.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DNA_pol_B PF00136.21 CAR24200.1 - 1.8e-145 485.2 0.8 2.4e-145 484.8 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CAR24200.1 - 6.5e-84 281.9 0.0 1.5e-83 280.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CAR24200.1 - 5.7e-18 65.1 5.0 1.1e-17 64.2 5.0 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CAR24200.1 - 1.8e-05 23.8 0.4 0.0013 17.7 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CAR24200.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CAR24200.1 - 0.0091 16.0 0.5 0.073 13.1 0.5 2.4 1 1 0 1 1 1 1 RNase_H superfamily Pkinase PF00069.25 CAR24201.1 - 1.5e-69 234.3 0.0 1.8e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24201.1 - 3.4e-36 124.9 0.0 4.4e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CAR24201.1 - 6.3e-08 32.8 0.3 1.3e-07 31.9 0.3 1.5 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 CAR24201.1 - 2.1e-06 26.8 0.0 5.3e-06 25.5 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR24201.1 - 0.00027 20.4 0.2 0.00039 19.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAR24201.1 - 0.00067 19.1 2.0 1.7 7.9 0.3 3.5 3 1 1 4 4 4 2 Kinase-like FTA2 PF13095.6 CAR24201.1 - 0.0033 17.1 0.5 0.066 12.8 0.1 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CAR24201.1 - 0.075 12.6 1.9 0.2 11.2 1.9 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 CAR24201.1 - 0.12 11.9 1.3 0.56 9.8 1.3 1.9 1 1 0 1 1 1 0 RIO1 family ATG16 PF08614.11 CAR24203.1 - 1.7e-17 64.4 13.7 2.4e-16 60.6 10.7 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CAR24203.1 - 0.00021 21.8 5.8 0.00025 21.5 5.8 1.2 1 0 0 1 1 1 1 Fez1 HIP1_clath_bdg PF16515.5 CAR24203.1 - 0.00025 21.6 3.8 0.00025 21.6 3.8 2.1 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 CCDC158 PF15921.5 CAR24203.1 - 0.00029 18.8 3.9 0.00032 18.7 3.9 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 GAS PF13851.6 CAR24203.1 - 0.0031 16.9 10.1 0.036 13.4 10.1 2.0 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 CAR24203.1 - 0.011 15.6 4.0 0.011 15.6 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Tho2 PF11262.8 CAR24203.1 - 0.013 14.7 5.3 0.013 14.7 5.3 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TMF_TATA_bd PF12325.8 CAR24203.1 - 0.015 15.5 5.8 0.015 15.5 5.8 1.5 2 0 0 2 2 1 0 TATA element modulatory factor 1 TATA binding HetR_C PF18460.1 CAR24203.1 - 0.033 14.1 0.3 0.06 13.3 0.3 1.5 1 1 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain DUF641 PF04859.12 CAR24203.1 - 0.049 14.0 5.4 0.026 14.8 3.2 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) HAUS-augmin3 PF14932.6 CAR24203.1 - 0.05 13.2 8.2 0.055 13.0 8.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 TolA_bind_tri PF16331.5 CAR24203.1 - 0.08 13.0 4.3 0.13 12.4 4.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF848 PF05852.11 CAR24203.1 - 0.084 13.0 4.0 0.1 12.7 4.0 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.6 CAR24203.1 - 0.14 11.5 2.5 0.16 11.3 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CAR24203.1 - 0.15 12.1 11.5 0.27 11.3 11.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 CAR24203.1 - 0.18 11.4 13.2 0.74 9.4 10.6 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cep57_MT_bd PF06657.13 CAR24203.1 - 0.19 12.2 6.0 1.8 9.1 0.9 2.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 CAR24203.1 - 0.2 12.2 13.0 0.26 11.8 13.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 CAR24203.1 - 0.32 10.1 8.3 0.35 9.9 8.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRS4 PF10422.9 CAR24203.1 - 0.36 10.4 8.6 0.31 10.6 7.7 1.5 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 DivIC PF04977.15 CAR24203.1 - 0.62 9.9 11.3 0.18 11.6 1.7 2.7 1 1 1 2 2 2 0 Septum formation initiator Swi5 PF07061.11 CAR24203.1 - 0.78 9.9 8.4 35 4.6 8.4 2.3 1 1 0 1 1 1 0 Swi5 GrpE PF01025.19 CAR24203.1 - 1.9 8.1 10.4 53 3.4 10.4 2.1 1 1 0 1 1 1 0 GrpE YabA PF06156.13 CAR24203.1 - 3.7 8.2 8.4 3.3 8.4 6.7 1.8 2 1 0 2 2 1 0 Initiation control protein YabA Cnn_1N PF07989.11 CAR24203.1 - 4.1 7.6 14.1 4.6 7.5 1.7 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Bap31_Bap29_C PF18035.1 CAR24203.1 - 4.1 7.5 11.6 16 5.6 5.5 3.3 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain ArsA_ATPase PF02374.15 CAR24204.1 - 3.2e-114 381.2 0.0 3.7e-114 381.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CAR24204.1 - 3.3e-11 43.4 0.1 2.1e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CAR24204.1 - 1.1e-07 32.0 0.0 2e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CAR24204.1 - 0.00079 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CAR24204.1 - 0.0037 16.8 1.7 0.026 14.0 0.5 2.6 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase AAA_24 PF13479.6 CAR24204.1 - 0.015 15.0 0.0 0.14 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CAR24204.1 - 0.034 13.8 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CAR24204.1 - 0.04 13.5 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF848 PF05852.11 CAR24205.1 - 0.0036 17.4 6.1 0.0036 17.4 6.1 3.2 2 1 1 3 3 3 1 Gammaherpesvirus protein of unknown function (DUF848) REF PF05755.12 CAR24205.1 - 4.2 7.1 8.2 1.1 9.0 0.9 2.3 2 0 0 2 2 2 0 Rubber elongation factor protein (REF) Ribosomal_S8 PF00410.19 CAR24206.1 - 5.6e-12 45.7 0.0 5.9e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 EDS1_EP PF18117.1 CAR24207.1 - 0.1 13.0 0.6 0.34 11.4 0.1 2.0 2 1 1 3 3 3 0 Enhanced disease susceptibility 1 protein EP domain zf-C2H2_jaz PF12171.8 CAR24208.1 - 4.9e-06 26.7 1.7 1e-05 25.7 1.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR24208.1 - 9.7e-06 25.8 1.3 1.7e-05 25.0 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 CAR24208.1 - 0.0056 16.8 1.2 0.012 15.7 1.2 1.5 1 0 0 1 1 1 1 DBF zinc finger SNRNP27 PF08648.12 CAR24208.1 - 0.048 13.7 0.4 0.11 12.6 0.4 1.6 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins DisA-linker PF10635.9 CAR24208.1 - 0.048 13.4 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region zf-C2H2_4 PF13894.6 CAR24208.1 - 0.083 13.8 0.8 0.19 12.7 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR24208.1 - 0.17 12.4 2.2 0.33 11.5 2.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type PNK3P PF08645.11 CAR24209.1 - 1.1e-38 132.4 0.1 2.3e-38 131.4 0.1 1.5 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase RPN6_N PF18055.1 CAR24210.1 - 5.8e-40 136.3 3.2 5.8e-40 136.3 3.2 3.1 3 1 1 4 4 4 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CAR24210.1 - 1.7e-17 63.9 0.0 7.1e-17 61.8 0.0 2.1 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 CAR24210.1 - 1.6e-12 46.9 0.0 4.8e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_16 PF13432.6 CAR24210.1 - 0.00066 20.3 1.7 0.29 11.8 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24210.1 - 0.0015 18.8 9.4 0.016 15.5 1.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF4398 PF14346.6 CAR24210.1 - 0.0019 18.8 0.6 0.63 10.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4398) TPR_19 PF14559.6 CAR24210.1 - 0.015 15.8 5.1 5.7 7.5 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR24210.1 - 0.049 13.0 0.2 0.1 12.0 0.2 1.5 1 0 0 1 1 1 0 MalT-like TPR region DDRGK PF09756.9 CAR24210.1 - 0.071 12.7 0.0 0.071 12.7 0.0 3.2 3 1 0 4 4 4 0 DDRGK domain TniB PF05621.11 CAR24210.1 - 0.079 12.4 0.1 0.74 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TPR_2 PF07719.17 CAR24210.1 - 2.6 8.4 14.4 3.6 7.9 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR24210.1 - 9.8 6.7 9.7 8.9 6.8 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat PMT PF02366.18 CAR24211.1 - 1.6e-81 273.5 18.9 1.6e-81 273.5 18.9 1.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR24211.1 - 9.3e-63 211.4 16.6 9.3e-63 211.4 16.6 2.4 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR24211.1 - 1.6e-46 158.5 0.8 3.1e-46 157.6 0.8 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 CAR24211.1 - 0.0016 18.7 15.8 0.0016 18.7 15.8 3.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MFS_1 PF07690.16 CAR24212.1 - 2.6e-13 49.6 15.1 3.3e-09 36.2 8.9 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CAR24212.1 - 7.5e-12 45.3 6.3 7.5e-12 45.3 6.3 2.1 3 0 0 3 3 3 1 Nodulin-like SRP14 PF02290.15 CAR24213.1 - 1.9e-19 69.8 0.0 1.9e-19 69.8 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein UBX PF00789.20 CAR24214.1 - 2.6e-14 53.2 0.0 5e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain Prenyltrans PF00432.21 CAR24215.1 - 6.9e-34 115.3 26.3 1.7e-10 40.5 0.7 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat RRM_1 PF00076.22 CAR24216.1 - 2.6e-19 68.8 5.4 3.3e-09 36.4 0.3 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR24216.1 - 0.011 15.9 0.1 2.9 8.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DUF1877 PF08974.10 CAR24216.1 - 0.078 13.1 0.3 0.17 12.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) HTH_Crp_2 PF13545.6 CAR24216.1 - 0.15 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain UPF0561 PF10573.9 CAR24216.1 - 0.34 11.0 4.6 0.26 11.4 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Herpes_DNAp_acc PF04929.12 CAR24216.1 - 7.2 5.5 11.5 9.9 5.0 0.5 2.2 2 0 0 2 2 2 0 Herpes DNA replication accessory factor NAD_binding_4 PF07993.12 CAR24217.1 - 1.5e-69 234.0 0.0 2.4e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CAR24217.1 - 2.5e-67 227.3 0.0 3.5e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CAR24217.1 - 1.6e-14 54.0 0.0 4.3e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CAR24217.1 - 8.8e-12 45.0 0.0 1.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR24217.1 - 8e-08 31.6 0.0 1.6e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Condensation PF00668.20 CAR24217.1 - 4.5e-05 22.3 0.0 0.01 14.5 0.0 2.3 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 CAR24217.1 - 5.8e-05 24.0 0.0 0.00027 21.9 0.0 2.3 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 CAR24217.1 - 0.0011 18.4 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CAR24217.1 - 0.0091 15.2 0.0 0.023 13.8 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein SNF2_N PF00176.23 CAR24218.1 - 7.3e-53 179.5 0.1 1.8e-52 178.2 0.1 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR24218.1 - 3.7e-16 59.4 0.0 7.2e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR24218.1 - 1.1e-09 38.5 0.1 2.4e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR24218.1 - 3.9e-08 33.2 0.0 8.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 CAR24218.1 - 2.5e-07 30.5 11.0 2.5e-07 30.5 11.0 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR24218.1 - 0.00084 19.1 9.5 0.00084 19.1 9.5 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAR24218.1 - 0.0018 18.5 5.4 0.0048 17.2 5.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CAR24218.1 - 0.0038 17.4 10.0 0.0038 17.4 10.0 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CAR24218.1 - 0.0051 16.6 8.0 0.0051 16.6 8.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR24218.1 - 0.0097 16.2 10.0 0.0097 16.2 10.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-Nse PF11789.8 CAR24218.1 - 0.034 14.0 5.6 0.076 12.8 5.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IL7 PF01415.16 CAR24218.1 - 0.036 14.1 0.2 0.088 12.8 0.2 1.6 1 0 0 1 1 1 0 Interleukin 7/9 family Zn_Tnp_IS91 PF14319.6 CAR24218.1 - 0.45 10.6 13.9 0.041 13.9 2.6 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain FYVE PF01363.21 CAR24218.1 - 3.3 7.9 10.4 3.4 7.9 1.9 2.7 2 0 0 2 2 2 0 FYVE zinc finger TPR_1 PF00515.28 CAR24219.1 - 6.1e-47 155.6 21.7 2e-07 30.5 0.0 10.4 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 CAR24219.1 - 4.4e-42 138.8 20.6 0.00012 21.9 0.0 9.9 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_17 PF13431.6 CAR24219.1 - 2.1e-29 99.7 21.1 0.00028 21.0 0.1 10.9 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 CAR24219.1 - 5.5e-27 91.7 16.2 0.027 14.6 0.0 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 CAR24219.1 - 3.9e-23 81.8 14.1 9.1e-05 23.0 2.9 6.7 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CAR24219.1 - 5.5e-21 74.0 22.0 0.00074 19.1 0.0 9.6 4 2 6 10 10 10 6 TPR repeat TPR_14 PF13428.6 CAR24219.1 - 3.3e-19 67.9 25.3 0.0063 17.2 0.3 10.0 4 3 6 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 CAR24219.1 - 3.9e-18 65.7 15.8 9.7e-05 22.8 1.2 6.8 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24219.1 - 3.7e-17 62.4 32.2 0.00045 20.5 0.3 8.0 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_9 PF13371.6 CAR24219.1 - 1.5e-15 57.1 19.1 0.0026 17.9 0.1 6.4 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 CAR24219.1 - 1.6e-15 55.9 25.1 0.0012 18.8 0.1 9.5 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 CAR24219.1 - 5.3e-14 51.8 19.0 0.45 11.3 0.0 9.6 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR24219.1 - 6.6e-12 45.5 9.8 0.00016 21.8 0.3 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CAR24219.1 - 1.4e-08 34.3 18.7 0.0039 16.4 0.1 4.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CAR24219.1 - 0.0011 18.7 19.6 0.23 11.4 0.5 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat SNAP PF14938.6 CAR24219.1 - 0.0019 17.6 10.8 0.31 10.4 0.1 4.5 3 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP ChAPs PF09295.10 CAR24219.1 - 0.015 14.3 0.9 0.68 8.9 0.2 2.5 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 CAR24219.1 - 1.7 7.5 0.0 1.7 7.5 0.0 4.4 4 1 0 4 4 4 0 NMDA receptor-regulated protein 1 AAA_16 PF13191.6 CAR24219.1 - 3.1 8.1 5.0 0.99 9.8 0.4 2.5 3 0 0 3 3 2 0 AAA ATPase domain EnY2 PF10163.9 CAR24220.1 - 2.7e-27 95.0 0.3 3.1e-27 94.8 0.3 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DEK_C PF08766.11 CAR24220.1 - 0.018 14.9 0.5 1.9 8.5 0.0 2.6 1 1 1 2 2 2 0 DEK C terminal domain Tcell_CD4_C PF12104.8 CAR24220.1 - 0.32 10.9 3.0 8.8 6.3 0.1 2.9 3 1 0 3 3 3 0 T cell CD4 receptor C terminal region NUDIX PF00293.28 CAR24221.1 - 6.1e-14 52.2 0.0 1.5e-13 50.9 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Med1 PF10744.9 CAR24222.1 - 1.5e-22 80.2 0.5 9.4e-21 74.3 0.2 2.1 1 1 1 2 2 2 2 Mediator of RNA polymerase II transcription subunit 1 Spermine_synth PF01564.17 CAR24223.1 - 4.7e-76 254.4 0.0 7.2e-76 253.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CAR24223.1 - 1.3e-25 89.0 0.1 2.4e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CAR24223.1 - 0.00035 21.2 0.0 0.00067 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR24223.1 - 0.0088 16.8 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CAR24223.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Hist_deacetyl PF00850.19 CAR24224.1 - 2.3e-71 240.8 0.0 3e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glycos_transf_1 PF00534.20 CAR24225.1 - 5.5e-11 42.3 0.0 2.7e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR24225.1 - 1.7e-06 28.2 0.0 3.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CAR24225.1 - 2.8e-06 27.8 0.0 1.1e-05 25.9 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CAR24225.1 - 0.094 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 YwcE PF17368.2 CAR24225.1 - 0.12 13.0 1.1 0.39 11.4 0.3 2.2 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE EF-hand_1 PF00036.32 CAR24226.1 - 8e-31 103.3 3.4 1.5e-08 33.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CAR24226.1 - 5.1e-27 94.1 0.1 2e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR24226.1 - 1.4e-26 90.1 2.6 2.7e-08 33.1 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CAR24226.1 - 8.7e-18 62.9 3.3 4.9e-07 29.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CAR24226.1 - 5.2e-17 61.4 4.5 1.1e-08 34.7 0.0 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CAR24226.1 - 8.7e-13 48.4 0.0 8.4e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CAR24226.1 - 2.8e-06 27.6 0.1 0.0021 18.4 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CAR24226.1 - 3.5e-05 24.1 0.1 0.26 11.6 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CAR24226.1 - 6.6e-05 23.0 0.3 0.025 14.7 0.1 2.5 1 1 1 2 2 2 2 Dockerin type I domain UPF0154 PF03672.13 CAR24226.1 - 8.7e-05 22.5 0.0 0.089 12.8 0.0 3.2 3 1 1 4 4 4 1 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 CAR24226.1 - 0.0015 18.5 0.0 0.6 10.0 0.0 2.8 1 1 2 3 3 3 1 Caleosin related protein DUF3349 PF11829.8 CAR24226.1 - 0.0023 18.7 0.4 1.7 9.4 0.0 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) TerB PF05099.13 CAR24226.1 - 0.0044 17.0 0.1 0.088 12.8 0.0 2.2 2 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_4 PF12763.7 CAR24226.1 - 0.013 15.5 0.2 0.033 14.1 0.1 1.7 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF853 PF05872.12 CAR24226.1 - 0.014 14.0 0.2 0.035 12.7 0.2 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SurA_N_3 PF13624.6 CAR24226.1 - 0.016 15.0 0.3 0.35 10.7 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain RNA_pol_Rpb4 PF03874.16 CAR24226.1 - 0.058 13.7 1.1 0.7 10.2 0.1 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb4 AAA_assoc_C PF09821.9 CAR24226.1 - 0.082 13.4 1.1 12 6.4 0.1 3.0 2 1 1 3 3 3 0 C-terminal AAA-associated domain EF-hand_11 PF08976.11 CAR24226.1 - 0.087 13.7 0.0 7.3 7.5 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Glycos_trans_3N PF02885.17 CAR24226.1 - 0.099 12.5 3.0 2.9 7.8 0.1 3.3 1 1 1 2 2 2 0 Glycosyl transferase family, helical bundle domain AIM3 PF17096.5 CAR24227.1 - 9.8e-27 93.7 5.8 9.8e-27 93.7 5.8 6.2 4 1 0 4 4 4 3 Altered inheritance of mitochondria protein 3 Fe-S_biosyn PF01521.20 CAR24229.1 - 1.2e-13 51.3 0.0 3.3e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis ThiF PF00899.21 CAR24230.1 - 6.6e-55 186.1 0.0 7.8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CAR24230.1 - 0.011 15.8 0.4 0.018 15.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pho88 PF10032.9 CAR24231.1 - 2.2e-81 271.5 0.1 2.5e-81 271.3 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) TMEM117 PF15113.6 CAR24231.1 - 0.061 12.3 0.1 0.077 11.9 0.1 1.1 1 0 0 1 1 1 0 TMEM117 protein family DUF884 PF05959.11 CAR24231.1 - 0.12 12.0 0.1 0.17 11.5 0.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) Ribosomal_L5_C PF00673.21 CAR24232.1 - 4.8e-22 77.9 0.0 7.8e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CAR24232.1 - 4.6e-19 68.5 0.0 1.2e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CAR24232.1 - 0.0029 17.3 0.1 0.0064 16.2 0.1 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain BCAS2 PF05700.11 CAR24233.1 - 3.8e-08 33.3 7.8 2.3e-07 30.7 7.8 1.9 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DDE_Tnp_ISL3 PF01610.17 CAR24233.1 - 0.096 12.4 0.7 0.11 12.2 0.7 1.1 1 0 0 1 1 1 0 Transposase Arrestin_N PF00339.29 CAR24235.1 - 2.1e-10 40.9 0.0 5.5e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain IF-2B PF01008.17 CAR24236.1 - 1.5e-102 342.6 0.0 2.6e-102 341.8 0.0 1.4 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF775 PF05603.12 CAR24236.1 - 1.1 8.8 4.7 2.3 7.7 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) NARP1 PF12569.8 CAR24236.1 - 1.7 7.5 11.6 2.4 7.0 11.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 L51_S25_CI-B8 PF05047.16 CAR24237.1 - 1e-14 54.1 0.1 1.6e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF4149 PF13664.6 CAR24238.1 - 0.0018 18.6 0.2 0.0067 16.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MAS20 PF02064.15 CAR24239.1 - 5.9e-39 133.1 0.6 8.2e-39 132.6 0.6 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor DUF2939 PF11159.8 CAR24239.1 - 0.032 14.6 0.2 0.081 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Draxin PF15550.6 CAR24239.1 - 0.061 13.2 0.1 0.072 12.9 0.1 1.1 1 0 0 1 1 1 0 Draxin MHC2-interact PF09307.10 CAR24239.1 - 0.082 12.9 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 CLIP, MHC2 interacting SLX9 PF15341.6 CAR24240.1 - 1.2e-25 90.4 10.1 1.9e-25 89.8 10.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DASH_Spc19 PF08287.11 CAR24240.1 - 2.1 8.2 9.9 6.3 6.7 5.0 2.8 1 1 1 2 2 2 0 Spc19 DUF3818 PF12825.7 CAR24241.1 - 5.2e-115 384.1 4.9 5.2e-115 384.1 4.9 1.9 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CAR24241.1 - 1.1e-41 141.8 4.3 3.1e-41 140.4 4.3 1.7 1 0 0 1 1 1 1 PX-associated PX PF00787.24 CAR24241.1 - 1.6e-10 41.0 2.2 1.6e-09 37.7 0.0 3.5 3 1 0 3 3 3 1 PX domain Anillin PF08174.11 CAR24241.1 - 0.69 10.3 5.4 21 5.5 0.0 3.9 4 0 0 4 4 4 0 Cell division protein anillin SirA PF10747.9 CAR24241.1 - 3.3 8.0 7.0 4 7.8 0.3 4.0 5 0 0 5 5 5 0 Sporulation inhibitor of replication protein SirA Sec7 PF01369.20 CAR24242.1 - 1.2e-28 100.1 0.8 4.9e-28 98.1 0.1 2.1 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 CAR24242.1 - 4e-05 24.1 0.3 0.00021 21.7 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 CAR24242.1 - 0.14 12.5 0.0 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PHF5 PF03660.14 CAR24243.1 - 8.1e-52 173.8 13.8 9e-52 173.7 13.8 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CAR24243.1 - 4 5.2 10.0 4.3 5.1 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_2 PF13639.6 CAR24244.1 - 5.3e-10 39.5 11.1 5.3e-10 39.5 11.1 3.5 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR24244.1 - 1.2e-07 31.4 9.8 1.2e-07 31.4 9.8 3.2 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR24244.1 - 4.3e-07 29.7 10.7 4.3e-07 29.7 10.7 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAR24244.1 - 1.4e-06 28.5 9.6 1.4e-06 28.5 9.6 3.2 2 1 1 3 3 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CAR24244.1 - 3e-05 23.6 6.2 3e-05 23.6 6.2 3.5 2 1 1 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CAR24244.1 - 0.00038 20.5 8.9 0.00038 20.5 8.9 3.4 3 1 1 4 4 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CAR24244.1 - 0.00042 20.3 8.2 0.00042 20.3 8.2 3.5 2 1 1 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CAR24244.1 - 0.012 15.6 5.8 0.012 15.6 5.8 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Peptidase_M60 PF13402.6 CAR24244.1 - 0.023 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like Zn_ribbon_17 PF17120.5 CAR24244.1 - 0.051 13.2 34.1 0.094 12.4 8.9 2.6 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 CAR24244.1 - 9.4 6.4 22.8 3.8 7.7 8.9 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger Cofilin_ADF PF00241.20 CAR24245.1 - 1.3e-29 102.4 0.0 9.1e-14 51.3 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4719 PF15843.5 CAR24246.1 - 0.23 11.5 0.6 0.35 10.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) PH_11 PF15413.6 CAR24247.1 - 8.8e-07 29.3 0.5 6e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CAR24247.1 - 0.025 15.1 0.0 0.078 13.5 0.0 2.0 1 0 0 1 1 1 0 PH domain MMM1 PF10296.9 CAR24247.1 - 0.03 13.4 0.0 0.03 13.4 0.0 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial morphology protein 1 PI3_PI4_kinase PF00454.27 CAR24248.1 - 4.2e-54 184.0 0.4 3e-53 181.2 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CAR24248.1 - 5.4e-24 84.1 0.3 3.7e-23 81.4 0.3 2.6 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 CAR24248.1 - 1.9e-12 46.8 0.1 4.3e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.6 CAR24248.1 - 0.03 15.2 0.0 0.13 13.1 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3385 PF11865.8 CAR24248.1 - 0.093 12.6 1.9 1.3 8.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) TPR_19 PF14559.6 CAR24248.1 - 0.12 12.8 0.0 0.45 11.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Urb2 PF10441.9 CAR24248.1 - 0.13 12.2 2.4 0.16 11.9 0.3 2.3 2 0 0 2 2 2 0 Urb2/Npa2 family CKS PF01111.19 CAR24249.1 - 3.9e-33 113.5 0.1 5.1e-33 113.1 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5_TIM PF17285.2 CAR24250.1 - 2.2e-68 230.2 0.5 3.5e-68 229.6 0.5 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 CAR24250.1 - 3.2e-64 216.0 0.1 7e-64 214.9 0.0 1.6 2 0 0 2 2 2 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 CAR24250.1 - 1.5e-57 194.2 0.0 2.3e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase DIL PF01843.19 CAR24251.1 - 4.4e-18 65.5 5.5 1.4e-16 60.6 5.5 2.7 1 1 0 1 1 1 1 DIL domain AA_permease PF00324.21 CAR24252.1 - 2.3e-119 399.1 29.6 2.9e-119 398.8 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR24252.1 - 1.9e-19 69.8 30.5 2.3e-19 69.5 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1712 PF08217.11 CAR24254.1 - 4.9e-148 494.3 8.4 5.7e-148 494.1 8.4 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Malt_amylase_C PF16657.5 CAR24254.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain SRP54 PF00448.22 CAR24255.1 - 7e-79 264.0 2.9 9.7e-78 260.3 0.9 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CAR24255.1 - 8.7e-30 103.3 9.6 8.7e-30 103.3 9.6 3.9 3 1 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 CAR24255.1 - 1.7e-14 53.7 3.0 4.7e-14 52.4 3.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRPRB PF09439.10 CAR24255.1 - 2e-05 24.1 0.8 1.2 8.5 0.0 3.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit cobW PF02492.19 CAR24255.1 - 7.4e-05 22.4 3.1 0.00039 20.1 1.3 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 CAR24255.1 - 9.2e-05 22.5 0.0 0.00035 20.6 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 CAR24255.1 - 0.00022 21.4 0.0 0.00058 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAR24255.1 - 0.00024 21.5 0.7 0.00093 19.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 CAR24255.1 - 0.0026 17.7 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 CAR24255.1 - 0.011 14.7 0.2 0.047 12.7 0.1 2.1 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CAR24255.1 - 0.015 15.9 0.0 0.065 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CAR24255.1 - 0.019 14.7 0.0 0.049 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain MipZ PF09140.11 CAR24255.1 - 0.019 14.3 0.4 0.66 9.2 0.1 2.7 2 1 0 2 2 2 0 ATPase MipZ AAA_22 PF13401.6 CAR24255.1 - 0.02 15.2 0.5 0.16 12.3 0.5 2.6 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CAR24255.1 - 0.024 14.4 0.1 0.087 12.6 0.1 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 CAR24255.1 - 0.024 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_31 PF13614.6 CAR24255.1 - 0.03 14.3 0.0 0.03 14.3 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CAR24255.1 - 0.031 14.0 0.1 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAR24255.1 - 0.038 14.4 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CLP1_P PF16575.5 CAR24255.1 - 0.063 13.1 0.7 14 5.4 0.0 2.8 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 CAR24255.1 - 0.073 13.3 0.2 0.5 10.6 0.0 2.4 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CAR24255.1 - 0.082 13.0 1.7 0.34 11.0 0.1 2.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase VirE PF05272.11 CAR24255.1 - 0.091 12.5 0.6 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Virulence-associated protein E Glycos_transf_2 PF00535.26 CAR24255.1 - 0.13 12.0 0.1 54 3.5 0.0 3.1 2 1 1 3 3 3 0 Glycosyl transferase family 2 ResIII PF04851.15 CAR24255.1 - 0.89 9.5 6.0 0.51 10.3 0.5 3.0 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit AAA PF00004.29 CAR24255.1 - 0.91 10.0 5.9 1.4 9.4 1.1 3.3 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 CAR24255.1 - 1.5 8.0 11.8 0.32 10.1 0.1 3.9 4 0 0 4 4 4 0 Anion-transporting ATPase NTPase_1 PF03266.15 CAR24255.1 - 1.6 8.6 6.8 4.8 7.1 3.0 3.1 2 1 0 2 2 2 0 NTPase SHE3 PF17078.5 CAR24256.1 - 5.4e-88 294.6 33.7 5.4e-88 294.6 33.7 1.5 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 Cnn_1N PF07989.11 CAR24256.1 - 0.012 15.8 4.9 0.012 15.8 4.9 4.1 1 1 4 5 5 5 0 Centrosomin N-terminal motif 1 GAS PF13851.6 CAR24256.1 - 0.028 13.8 26.3 0.029 13.7 24.1 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2353 PF09789.9 CAR24256.1 - 0.03 13.7 23.8 0.044 13.1 12.3 2.3 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) E3_UbLigase_EDD PF11547.8 CAR24256.1 - 0.036 13.8 0.3 0.12 12.1 0.3 1.9 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Csm1_N PF18504.1 CAR24256.1 - 0.046 14.0 23.8 0.13 12.6 1.3 5.2 1 1 3 5 5 5 0 Csm1 N-terminal domain Tropomyosin PF00261.20 CAR24256.1 - 0.26 10.6 18.2 0.11 11.8 11.3 2.9 2 1 1 3 3 3 0 Tropomyosin Rootletin PF15035.6 CAR24256.1 - 0.26 11.3 27.6 1.4 8.9 4.3 3.3 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Jnk-SapK_ap_N PF09744.9 CAR24256.1 - 0.32 11.2 27.3 3.9 7.7 12.0 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 CAR24256.1 - 0.38 10.8 14.2 0.16 12.0 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4168 PF13767.6 CAR24256.1 - 0.44 11.8 0.1 0.44 11.8 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4168) APG6_N PF17675.1 CAR24256.1 - 0.56 10.7 27.0 1.6 9.3 9.0 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF641 PF04859.12 CAR24256.1 - 0.93 9.8 16.8 0.042 14.2 7.5 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 CAR24256.1 - 1.4 9.0 28.9 1.1 9.2 9.3 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 CAR24256.1 - 1.8 8.4 6.0 1.1 9.2 0.7 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GIDA_assoc PF13932.6 CAR24256.1 - 2.7 8.1 14.2 3.4 7.8 13.1 1.7 1 1 0 1 1 1 0 GidA associated domain Tup_N PF08581.10 CAR24256.1 - 2.8 8.3 20.2 0.8 10.0 10.7 3.5 2 1 2 4 4 4 0 Tup N-terminal TPR_MLP1_2 PF07926.12 CAR24256.1 - 4.5 7.3 36.6 0.31 11.1 5.2 5.0 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein Prp19 PF08606.11 CAR24256.1 - 9.7 6.3 8.2 9.5 6.3 0.6 3.1 3 0 0 3 3 3 0 Prp19/Pso4-like PH PF00169.29 CAR24257.1 - 1.6e-15 57.5 0.5 2.9e-07 30.9 0.1 2.5 2 0 0 2 2 2 2 PH domain PH_15 PF17339.2 CAR24257.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.6 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 CAR24257.1 - 0.016 15.6 7.1 0.15 12.5 1.5 3.6 2 2 2 4 4 4 0 Pleckstrin homology domain WD40 PF00400.32 CAR24258.1 - 0.0013 19.5 0.1 0.25 12.3 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Ras PF00071.22 CAR24259.1 - 0.0034 17.0 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 CAR24259.1 - 0.027 14.6 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 CAR24259.1 - 0.065 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Atg14 PF10186.9 CAR24260.1 - 4.8e-20 71.9 10.6 1.1e-19 70.6 10.6 1.5 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 PEP-utilisers_N PF05524.13 CAR24260.1 - 0.015 15.4 1.5 0.025 14.7 1.1 1.5 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Fib_alpha PF08702.10 CAR24260.1 - 0.16 12.2 5.4 0.099 12.8 3.0 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Takusan PF04822.13 CAR24260.1 - 0.55 10.1 5.3 0.21 11.5 1.5 2.3 2 1 0 2 2 2 0 Takusan CENP-H PF05837.12 CAR24260.1 - 0.62 10.5 9.9 1.3 9.4 5.5 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 CAR24260.1 - 1.7 8.1 8.2 2.3 7.7 8.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit COG2 PF06148.11 CAR24260.1 - 1.9 8.6 6.8 1.1 9.3 4.7 1.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin PF02996.17 CAR24260.1 - 4.4 7.2 8.3 0.18 11.7 0.8 2.4 3 0 0 3 3 3 0 Prefoldin subunit ATP-synt_ab PF00006.25 CAR24261.1 - 1e-65 221.4 0.0 1.5e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CAR24261.1 - 3.8e-15 56.2 1.9 8e-15 55.1 1.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 CAR24261.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Glyco_transf_20 PF00982.21 CAR24263.1 - 1.1e-203 677.2 0.1 1.3e-203 677.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 CAR24263.1 - 8.6e-05 23.0 0.1 0.00037 20.9 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CAR24263.1 - 0.00031 20.3 3.2 0.035 13.6 0.1 3.4 3 1 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CAR24263.1 - 0.029 14.1 0.3 0.059 13.0 0.1 1.6 2 0 0 2 2 2 0 Starch synthase catalytic domain PP2C PF00481.21 CAR24264.1 - 4.7e-66 223.1 0.0 1.4e-65 221.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CAR24264.1 - 0.0052 16.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CAR24264.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Tau95 PF09734.9 CAR24265.1 - 9.9e-34 117.1 0.3 2.3e-33 115.9 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CAR24265.1 - 3.3e-22 79.0 0.0 7.1e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain Ribosomal_L31 PF01197.18 CAR24266.1 - 0.0007 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Me-amine-dh_H PF06433.11 CAR24266.1 - 0.071 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) DIM1 PF02966.16 CAR24267.1 - 2e-69 231.5 1.0 2.2e-69 231.4 1.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CAR24267.1 - 0.00088 19.2 0.1 0.0012 18.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin SHQ1 PF04925.15 CAR24267.1 - 0.11 12.1 0.3 0.17 11.4 0.1 1.4 2 0 0 2 2 2 0 SHQ1 protein DUF3192 PF11399.8 CAR24267.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) HGTP_anticodon PF03129.20 CAR24268.1 - 2.7e-21 75.5 0.3 7.9e-21 74.0 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CAR24268.1 - 6.7e-07 29.4 0.0 2e-06 27.9 0.1 2.0 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF5089 PF17002.5 CAR24269.1 - 0.021 14.7 1.6 0.022 14.6 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) Aida_N PF08910.10 CAR24269.1 - 0.17 12.3 1.4 0.58 10.6 0.1 2.2 2 1 1 3 3 3 0 Aida N-terminus RRM_1 PF00076.22 CAR24270.1 - 3.2e-09 36.5 0.0 1.9e-07 30.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RecX PF02631.16 CAR24270.1 - 0.13 12.7 1.4 0.36 11.3 1.4 1.8 1 0 0 1 1 1 0 RecX family GTP_EFTU PF00009.27 CAR24271.1 - 6.9e-55 185.6 0.0 1.1e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAR24271.1 - 9.4e-42 141.9 0.0 2.3e-41 140.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAR24271.1 - 1.6e-13 50.8 1.7 1.6e-13 50.8 1.7 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR24271.1 - 0.00049 20.2 0.2 0.011 15.8 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CAR24271.1 - 0.2 11.6 4.5 0.077 12.9 0.8 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 CIMR PF00878.18 CAR24272.1 - 3.5e-12 46.6 0.1 5.6e-05 23.3 0.1 2.8 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 CAR24272.1 - 4.8e-05 23.1 0.0 7.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.15 CAR24272.1 - 9.8e-05 21.6 0.0 0.00013 21.2 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 CAR24272.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 1 0 1 1 1 0 Autophagy-related protein 27 DUF3074 PF11274.8 CAR24273.1 - 5.3e-28 98.2 0.2 7.3e-28 97.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Opy2 PF09463.10 CAR24274.1 - 5.7e-10 39.3 20.1 8.5e-10 38.8 20.1 1.3 1 0 0 1 1 1 1 Opy2 protein SKG6 PF08693.10 CAR24274.1 - 0.018 14.4 1.2 0.038 13.4 1.2 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2207 PF09972.9 CAR24274.1 - 0.067 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 CAR24274.1 - 0.07 11.9 0.0 0.07 11.9 0.0 2.4 2 1 1 3 3 3 0 Amnionless Trp_oprn_chp PF09534.10 CAR24274.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.4 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SUZ PF12752.7 CAR24274.1 - 0.26 12.1 5.7 1 10.1 0.0 3.7 4 0 0 4 4 4 0 SUZ domain Ephrin_rec_like PF07699.13 CAR24274.1 - 7 6.5 15.1 68 3.3 15.1 2.4 1 1 0 1 1 1 0 Putative ephrin-receptor like TraT PF05818.12 CAR24274.1 - 10 5.8 6.9 5 6.8 2.0 2.4 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Transketolase_N PF00456.21 CAR24275.1 - 8.2e-157 521.4 0.0 1.3e-156 520.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CAR24275.1 - 1.2e-45 155.4 0.0 2e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CAR24275.1 - 9.9e-14 51.3 0.0 2e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 CAR24275.1 - 0.0016 18.2 0.1 0.038 13.8 0.1 2.8 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CAR24275.1 - 0.0035 16.6 0.1 0.017 14.3 0.1 1.9 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase LMWPc PF01451.21 CAR24276.1 - 5.5e-46 156.5 0.0 6.2e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Not3 PF04065.15 CAR24277.1 - 6.3e-64 215.6 42.5 3.3e-63 213.2 34.1 3.0 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CAR24277.1 - 4.9e-39 133.4 1.0 4.9e-39 133.4 1.0 3.1 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family PCRF PF03462.18 CAR24277.1 - 2 8.2 21.0 0.48 10.3 4.2 3.2 3 0 0 3 3 3 0 PCRF domain Mito_carr PF00153.27 CAR24278.1 - 1.7e-58 194.5 4.2 4.9e-22 77.7 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_PH PF01138.21 CAR24279.1 - 6.2e-20 72.0 0.0 1e-19 71.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAR24279.1 - 3.5e-07 30.1 0.4 8.2e-07 29.0 0.2 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 tRNA-synt_1 PF00133.22 CAR24280.1 - 2.5e-234 779.0 0.0 3e-233 775.5 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CAR24280.1 - 2.4e-31 108.8 1.4 7.4e-31 107.2 1.4 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CAR24280.1 - 2.4e-14 52.9 0.2 2.6e-07 29.8 0.0 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CAR24280.1 - 1.2e-09 37.9 0.0 1.5e-08 34.4 0.0 3.4 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Lzipper-MIP1 PF14389.6 CAR24280.1 - 0.00045 20.5 0.6 0.0012 19.1 0.6 1.7 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 tRNA-synt_1e PF01406.19 CAR24280.1 - 0.0034 16.8 0.5 0.91 8.8 0.0 3.1 3 1 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CAR24280.1 - 0.055 12.8 0.0 0.61 9.4 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Val_tRNA-synt_C PF10458.9 CAR24280.1 - 2.3 8.6 14.9 0.1 12.9 3.7 3.1 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm APG6_N PF17675.1 CAR24280.1 - 2.3 8.7 12.1 6.9 7.2 1.1 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region RRM_1 PF00076.22 CAR24281.1 - 1.4e-67 223.5 11.0 1e-16 60.5 0.1 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR24281.1 - 3.9e-07 29.7 0.0 0.0005 19.7 0.0 3.8 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR24281.1 - 0.001 19.2 0.2 14 5.8 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CAR24281.1 - 0.0014 18.6 0.0 15 5.6 0.0 4.6 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CAR24281.1 - 0.0018 18.1 0.0 4.2 7.3 0.0 3.6 4 0 0 4 4 4 2 Occluded RNA-recognition motif DUF4944 PF16302.5 CAR24281.1 - 0.0072 16.4 0.3 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4944) CwfJ_C_1 PF04677.15 CAR24282.1 - 9.9e-29 99.7 0.1 1.8e-28 98.8 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CAR24282.1 - 9.3e-14 52.1 0.7 2e-13 51.0 0.7 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-UBP_var PF17807.1 CAR24282.1 - 0.024 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger Pkinase PF00069.25 CAR24283.1 - 1.3e-55 188.6 0.0 6.6e-55 186.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24283.1 - 1.6e-27 96.4 0.1 1.7e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 CAR24283.1 - 0.00013 22.6 0.4 0.00037 21.1 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CAR24283.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAR24283.1 - 0.0089 15.4 0.0 0.059 12.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAR24283.1 - 0.018 14.4 0.2 0.045 13.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nop PF01798.18 CAR24284.1 - 1.2e-60 204.9 0.0 2.1e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CAR24284.1 - 1.1e-25 90.9 6.9 2.1e-25 90.0 6.9 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain RNA_pol_A_bac PF01000.26 CAR24285.1 - 6.2e-29 100.6 0.0 1.4e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CAR24285.1 - 5.1e-20 70.7 0.0 7.5e-20 70.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain FAD_binding_2 PF00890.24 CAR24285.1 - 0.0092 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Prot_ATP_OB_N PF17758.1 CAR24285.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain DUF1746 PF08508.10 CAR24286.1 - 5.1e-08 33.2 3.9 6.5e-06 26.5 3.9 2.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Nrap_D5 PF17406.2 CAR24287.1 - 1.4e-53 181.0 0.0 2.9e-53 179.9 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CAR24287.1 - 4.8e-49 166.6 0.1 7.6e-49 166.0 0.1 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 CAR24287.1 - 4.3e-48 162.9 0.1 6.2e-46 155.9 0.1 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 CAR24287.1 - 9.5e-44 149.1 1.2 9.5e-44 149.1 1.2 2.2 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 CAR24287.1 - 6.6e-41 140.0 0.1 1.3e-40 139.1 0.1 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 CAR24287.1 - 3.8e-29 101.6 0.1 7.8e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 Lipoprotein_20 PF13942.6 CAR24288.1 - 0.0024 17.8 1.8 0.0024 17.8 1.8 3.5 2 1 2 4 4 4 1 YfhG lipoprotein DUF2353 PF09789.9 CAR24288.1 - 0.0075 15.7 10.6 0.0075 15.7 10.6 2.5 3 0 0 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) Seryl_tRNA_N PF02403.22 CAR24288.1 - 3.3 8.0 32.8 1.1 9.5 10.9 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 CAR24288.1 - 4.5 7.3 15.0 0.32 11.0 6.1 2.8 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 CAR24288.1 - 5.7 6.3 38.1 19 4.6 37.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) FHIPEP PF00771.20 CAR24288.1 - 8 4.8 12.6 15 3.8 12.6 1.4 1 0 0 1 1 1 0 FHIPEP family Catalase PF00199.19 CAR24289.1 - 2.8e-172 573.1 0.0 3.5e-172 572.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CAR24289.1 - 2e-10 40.7 0.0 6e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive RPN7 PF10602.9 CAR24290.1 - 2.5e-57 193.4 4.2 4.7e-57 192.5 4.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CAR24290.1 - 1.4e-16 60.9 0.5 3.5e-16 59.6 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.6 CAR24290.1 - 0.0014 18.7 1.8 0.0019 18.2 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR24290.1 - 0.0021 18.6 0.2 0.054 14.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Interferon PF00143.19 CAR24290.1 - 0.0043 17.3 0.6 0.0089 16.2 0.6 1.6 1 0 0 1 1 1 1 Interferon alpha/beta domain TPR_14 PF13428.6 CAR24290.1 - 0.024 15.4 0.1 1 10.4 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 CAR24290.1 - 0.037 13.3 1.2 0.13 11.5 0.7 1.9 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR24290.1 - 0.056 13.6 2.6 0.24 11.6 0.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24290.1 - 0.059 13.7 1.4 0.72 10.2 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR24290.1 - 0.14 12.3 0.0 19 5.6 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat EMP24_GP25L PF01105.24 CAR24291.1 - 1.4e-33 116.4 0.0 1.8e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1963 PF09234.10 CAR24292.1 - 6.5e-57 193.4 0.1 7.6e-57 193.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) TP6A_N PF04406.14 CAR24293.1 - 7.4e-14 51.5 4.6 4.5e-13 49.0 0.5 3.5 4 0 0 4 4 4 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 CAR24293.1 - 0.0006 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) Spore_III_AB PF09548.10 CAR24293.1 - 0.034 14.3 0.0 0.19 11.8 0.0 2.2 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TauD PF02668.16 CAR24294.1 - 1.1e-44 153.2 0.0 1.5e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CAR24294.1 - 0.00024 21.7 0.0 0.00053 20.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 CAR24294.1 - 0.15 11.1 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 CsiD Pet127 PF08634.10 CAR24295.1 - 4.2e-111 370.8 8.8 7.7e-111 369.9 8.8 1.4 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PQ-loop PF04193.14 CAR24296.1 - 1.5e-09 37.5 14.3 1.3e-08 34.4 2.2 3.2 3 1 0 3 3 3 2 PQ loop repeat ARD PF03079.14 CAR24297.1 - 2.1e-43 148.2 0.0 2.4e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CAR24297.1 - 1.2e-10 41.0 0.0 1.9e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CAR24297.1 - 5.7e-07 29.5 0.0 8.5e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CAR24297.1 - 0.0009 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 CAR24297.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Cupin_3 PF05899.12 CAR24297.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Glyco_hydro_72 PF03198.14 CAR24298.1 - 5.4e-143 476.0 10.4 7.3e-143 475.5 10.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CAR24298.1 - 1.9e-05 24.3 0.3 7.7e-05 22.3 0.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Macoilin PF09726.9 CAR24298.1 - 0.16 10.5 9.8 0.21 10.1 9.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF908 PF06012.12 CAR24298.1 - 1.1 8.6 7.1 1.9 7.8 7.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Apt1 PF10351.9 CAR24298.1 - 6.2 5.5 8.3 8.7 5.1 8.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hap4_Hap_bind PF10297.9 CAR24299.1 - 5.9e-08 32.6 1.8 1.9e-07 30.9 1.8 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 CAR24299.1 - 3.2e-06 27.1 12.8 2.4e-05 24.4 6.4 2.3 1 1 1 2 2 2 2 bZIP transcription factor FAM184 PF15665.5 CAR24299.1 - 0.00054 19.8 3.3 0.00076 19.3 3.3 1.1 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B DUF812 PF05667.11 CAR24299.1 - 0.0023 16.9 0.9 0.0029 16.6 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 CAR24299.1 - 0.011 15.8 2.1 0.017 15.2 2.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_Xtn PF12848.7 CAR24299.1 - 0.035 14.1 5.6 0.067 13.2 5.6 1.4 1 0 0 1 1 1 0 ABC transporter bZIP_Maf PF03131.17 CAR24299.1 - 0.043 14.3 6.6 0.93 10.1 8.3 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF641 PF04859.12 CAR24299.1 - 0.047 14.0 5.3 0.07 13.5 5.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Laminin_II PF06009.12 CAR24299.1 - 0.052 13.6 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF3450 PF11932.8 CAR24299.1 - 0.08 12.2 0.6 0.11 11.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-Q PF13094.6 CAR24299.1 - 0.089 13.0 2.7 0.15 12.2 2.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.11 CAR24299.1 - 0.1 11.5 2.8 0.14 11.0 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 CAR24299.1 - 0.11 12.8 0.7 0.19 12.0 0.7 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TEX13 PF15186.6 CAR24299.1 - 0.14 11.8 2.4 0.23 11.1 2.4 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF1664 PF07889.12 CAR24299.1 - 0.26 11.4 0.6 0.37 10.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 CAR24299.1 - 0.27 11.3 2.0 0.36 10.9 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_2 PF07716.15 CAR24299.1 - 0.28 11.3 14.6 1.9 8.6 7.3 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Lebercilin PF15619.6 CAR24299.1 - 0.34 10.6 8.7 0.48 10.1 8.7 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease WSC PF01822.19 CAR24300.1 - 6.4e-12 45.5 15.5 6.4e-12 45.5 15.5 2.7 2 1 0 2 2 2 1 WSC domain DUF5305 PF17231.2 CAR24300.1 - 0.001 18.5 0.2 0.0031 17.0 0.2 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF5305) SOG2 PF10428.9 CAR24300.1 - 0.0022 17.3 22.0 0.0026 17.0 22.0 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein CD34_antigen PF06365.12 CAR24300.1 - 0.0025 17.4 0.0 0.0061 16.2 0.0 1.6 1 0 0 1 1 1 1 CD34/Podocalyxin family Nitrate_red_gam PF02665.14 CAR24300.1 - 0.0029 17.2 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF2207 PF09972.9 CAR24300.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Hamartin PF04388.12 CAR24300.1 - 0.34 9.5 18.0 0.37 9.4 18.0 1.2 1 0 0 1 1 1 0 Hamartin protein Rrn6 PF10214.9 CAR24300.1 - 0.34 9.4 19.3 0.51 8.8 19.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4366 PF14283.6 CAR24300.1 - 0.78 9.8 4.4 3.1 7.8 4.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) PPP4R2 PF09184.11 CAR24300.1 - 1.4 8.5 9.1 2 8.0 9.1 1.2 1 0 0 1 1 1 0 PPP4R2 Mid2 PF04478.12 CAR24300.1 - 4.6 7.1 8.5 0.093 12.6 0.5 2.1 1 1 0 2 2 2 0 Mid2 like cell wall stress sensor DUF2408 PF10303.9 CAR24301.1 - 2e-64 216.2 14.4 2e-46 157.9 0.7 4.8 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) Osmo_CC PF08946.10 CAR24301.1 - 0.0051 17.0 1.0 0.061 13.6 0.0 2.8 2 0 0 2 2 2 1 Osmosensory transporter coiled coil FAA_hydro_N_2 PF18288.1 CAR24301.1 - 0.066 13.6 0.1 23 5.5 0.1 3.7 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 MtrG PF04210.13 CAR24301.1 - 0.088 12.7 0.2 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Laminin_II PF06009.12 CAR24301.1 - 0.15 12.1 2.9 20 5.2 0.1 4.2 4 1 1 5 5 5 0 Laminin Domain II DASH_Dad3 PF08656.10 CAR24301.1 - 1.2 9.3 5.4 2.1 8.5 0.6 3.2 3 0 0 3 3 3 0 DASH complex subunit Dad3 NPV_P10 PF05531.12 CAR24301.1 - 1.4 9.5 6.9 27 5.3 0.2 4.9 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein AATF-Che1 PF13339.6 CAR24301.1 - 2.1 9.0 10.9 1.8 9.3 0.9 4.2 2 2 3 5 5 5 0 Apoptosis antagonizing transcription factor DUF4559 PF15112.6 CAR24301.1 - 2.9 7.5 8.7 5.5 6.6 3.3 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4559) AhpC-TSA PF00578.21 CAR24302.1 - 2e-28 98.8 0.0 2.9e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR24302.1 - 3.3e-20 72.3 0.1 5.1e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CAR24302.1 - 0.0022 18.1 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Arm-DNA-bind_3 PF13356.6 CAR24302.1 - 0.063 13.7 0.4 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Arm DNA-binding domain Adap_comp_sub PF00928.21 CAR24303.1 - 9.4e-92 307.1 0.2 9.4e-92 307.1 0.2 1.3 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAR24303.1 - 5.3e-05 23.2 0.7 9.4e-05 22.4 0.7 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CAR24303.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain TPP1 PF10341.9 CAR24304.1 - 0.00021 21.2 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Urm1 PF09138.11 CAR24305.1 - 1.1e-36 125.1 0.5 1.2e-36 124.9 0.5 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CAR24305.1 - 0.013 16.2 0.0 0.016 15.9 0.0 1.2 1 0 0 1 1 1 0 ThiS family YchF-GTPase_C PF06071.13 CAR24305.1 - 0.17 12.1 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Nas2_N PF18265.1 CAR24306.1 - 3.2e-23 81.5 0.2 5.4e-23 80.7 0.2 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 CAR24306.1 - 0.04 14.3 0.1 0.096 13.0 0.1 1.7 1 1 0 1 1 1 0 PDZ domain GRASP55_65 PF04495.14 CAR24306.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain bZIP_2 PF07716.15 CAR24307.1 - 7.4e-13 48.4 9.6 1.1e-12 47.8 9.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CAR24307.1 - 6.4e-09 35.8 10.4 1.1e-08 35.1 10.4 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CAR24307.1 - 0.00071 20.1 6.1 0.0013 19.2 6.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor FAM76 PF16046.5 CAR24307.1 - 0.024 14.0 0.9 0.033 13.5 0.9 1.1 1 0 0 1 1 1 0 FAM76 protein TSC22 PF01166.18 CAR24307.1 - 0.088 13.1 0.8 0.15 12.4 0.8 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.15 CAR24307.1 - 0.19 11.5 3.7 0.33 10.8 3.7 1.4 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 CAR24307.1 - 0.26 11.9 1.2 0.41 11.3 1.2 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Gti1_Pac2 PF09729.9 CAR24308.1 - 8.5e-45 153.1 0.4 3.2e-40 138.2 0.1 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family Mito_carr PF00153.27 CAR24309.1 - 9.2e-73 240.3 2.1 6.1e-25 87.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR24309.1 - 0.061 12.5 4.7 0.15 11.2 0.1 3.1 3 1 1 4 4 4 0 Gammaproteobacterial serine protease Ytca PF17090.5 CAR24309.1 - 0.18 12.4 1.2 1 9.9 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family Thioredoxin PF00085.20 CAR24310.1 - 1.3e-22 79.7 1.1 1.2e-18 66.9 0.0 3.5 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CAR24310.1 - 6.7e-05 22.9 2.6 0.00034 20.6 0.4 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CAR24310.1 - 0.0012 18.2 7.3 0.022 14.1 0.1 3.8 4 0 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CAR24310.1 - 0.046 14.2 1.5 4.5 7.8 0.0 3.3 3 0 0 3 3 3 0 Thioredoxin-like domain Use1 PF09753.9 CAR24311.1 - 0.00041 20.2 0.0 0.00048 19.9 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 FixQ PF05545.11 CAR24311.1 - 0.28 11.2 2.5 0.52 10.3 2.5 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ ParA PF10609.9 CAR24312.1 - 1.9e-98 328.8 0.0 2.1e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CAR24312.1 - 2.3e-10 40.6 0.0 1.3e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAR24312.1 - 5.8e-08 32.8 1.1 9e-07 29.0 1.1 2.3 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 CAR24312.1 - 3.5e-06 26.4 0.3 2.2e-05 23.8 0.4 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 CAR24312.1 - 4.1e-06 26.3 0.1 3.1e-05 23.4 0.1 2.2 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 CAR24312.1 - 0.0018 17.7 0.4 0.017 14.6 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 CAR24312.1 - 0.0027 16.7 0.2 0.0044 16.0 0.2 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CAR24312.1 - 0.008 15.8 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 CAR24312.1 - 0.011 15.2 0.1 0.05 13.1 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 CAR24312.1 - 0.13 12.1 0.5 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF3496 PF12001.8 CAR24313.1 - 0.51 10.7 6.9 7.1 7.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) UAA PF08449.11 CAR24314.1 - 2.7e-81 273.1 18.2 3.1e-81 272.9 18.2 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CAR24314.1 - 3.3e-05 24.1 24.4 0.0005 20.3 10.6 2.5 2 1 0 2 2 2 2 EamA-like transporter family DUF3525 PF12039.8 CAR24314.1 - 0.0063 15.3 0.0 0.009 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3525) Tmemb_14 PF03647.13 CAR24314.1 - 0.055 14.2 1.3 0.055 14.2 1.3 3.6 2 1 0 2 2 2 0 Transmembrane proteins 14C TPT PF03151.16 CAR24314.1 - 2.1 7.6 17.3 73 2.6 17.3 2.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family Prefoldin_2 PF01920.20 CAR24315.1 - 3.3e-22 78.4 2.6 3.6e-22 78.3 2.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.9 CAR24315.1 - 0.02 14.9 4.3 0.55 10.3 0.3 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.5 CAR24315.1 - 0.043 14.1 2.1 0.82 10.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF2383 PF09537.10 CAR24315.1 - 0.048 14.0 0.2 0.091 13.1 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Prefoldin PF02996.17 CAR24315.1 - 0.049 13.6 1.9 2.7 7.9 0.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit ZapB PF06005.12 CAR24315.1 - 0.28 11.7 3.6 4 7.9 0.4 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DDOST_48kD PF03345.14 CAR24316.1 - 3.1e-131 438.0 1.6 3.6e-131 437.8 1.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Exonuc_VII_S PF02609.16 CAR24317.1 - 0.0096 16.0 0.8 0.018 15.1 0.8 1.5 1 0 0 1 1 1 1 Exonuclease VII small subunit HTH_57 PF18679.1 CAR24317.1 - 0.027 14.8 0.3 0.033 14.5 0.3 1.2 1 0 0 1 1 1 0 ThcOx helix turn helix domain Spc24 PF08286.11 CAR24317.1 - 0.032 14.5 0.4 0.052 13.8 0.4 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2951 PF11166.8 CAR24317.1 - 0.078 13.2 0.3 0.098 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) CHDCT2 PF08074.11 CAR24317.1 - 0.11 12.7 0.4 0.14 12.3 0.4 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain SpmSyn_N PF17950.1 CAR24317.1 - 0.14 12.4 0.4 0.22 11.7 0.3 1.4 1 1 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal Syja_N PF02383.18 CAR24318.1 - 2.8e-49 168.2 0.0 5e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CAR24318.1 - 6.6e-13 48.7 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pox_A_type_inc PF04508.12 CAR24318.1 - 0.052 13.4 0.1 0.17 11.8 0.1 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat BTB PF00651.31 CAR24319.1 - 4.6e-19 68.7 0.1 1.2e-09 38.3 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 CAR24319.1 - 4.9e-05 23.8 0.2 0.00019 21.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR24319.1 - 0.0001 22.8 0.0 0.00031 21.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR24319.1 - 0.00046 20.4 0.1 0.0012 19.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CAR24319.1 - 0.0012 19.2 0.0 0.013 15.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CAR24319.1 - 0.0042 17.5 0.1 0.066 13.8 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Wzt_C PF14524.6 CAR24320.1 - 0.042 13.9 0.1 0.06 13.4 0.1 1.2 1 0 0 1 1 1 0 Wzt C-terminal domain RRM_1 PF00076.22 CAR24321.1 - 1.7e-13 50.2 0.1 2.7e-13 49.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR24321.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CAR24321.1 - 0.0019 18.1 0.0 0.0043 17.0 0.0 1.6 2 0 0 2 2 2 1 RL domain RRM_Rrp7 PF17799.1 CAR24321.1 - 0.0086 15.9 0.2 0.012 15.4 0.2 1.5 1 1 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CAR24321.1 - 0.037 14.2 0.1 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 CAR24321.1 - 0.047 13.5 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nop16 PF09420.10 CAR24322.1 - 1.3e-63 214.8 4.4 1.6e-63 214.6 4.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PMI_typeI PF01238.21 CAR24323.1 - 2.4e-151 504.2 0.0 2.7e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 CAR24323.1 - 0.00079 19.3 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Hexapep PF00132.24 CAR24324.1 - 0.016 14.9 10.4 0.51 10.1 0.7 4.9 4 1 2 6 6 6 0 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CAR24324.1 - 9.8 6.0 14.0 0.32 10.8 0.4 4.2 3 2 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase GDA1_CD39 PF01150.17 CAR24325.1 - 2.7e-137 457.9 0.0 3.8e-137 457.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family TauE PF01925.19 CAR24325.1 - 0.071 12.7 0.2 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DsbD_2 PF13386.6 CAR24325.1 - 0.16 11.9 0.3 0.27 11.1 0.3 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region TFIIB PF00382.19 CAR24326.1 - 1.1e-47 160.0 5.3 6.6e-26 90.2 1.1 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CAR24326.1 - 1.3e-11 43.8 0.8 2.3e-11 43.0 0.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 CAR24326.1 - 0.0033 17.5 0.0 0.012 15.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain zf-ribbon_3 PF13248.6 CAR24326.1 - 0.16 11.4 3.3 4.8 6.7 3.3 2.5 1 1 0 1 1 1 0 zinc-ribbon domain GN3L_Grn1 PF08701.11 CAR24327.1 - 6.2e-23 80.7 15.8 6.2e-23 80.7 15.8 1.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CAR24327.1 - 2e-18 66.5 0.1 2.8e-14 53.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR24327.1 - 2.2e-09 37.0 0.1 1.5e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CAR24327.1 - 0.00013 22.1 7.0 0.14 12.2 0.3 3.6 2 2 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 CAR24327.1 - 0.00018 21.4 0.1 0.004 17.1 0.1 2.5 1 1 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 CAR24327.1 - 0.00063 20.3 0.2 0.014 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 CAR24327.1 - 0.0018 17.7 0.0 0.0065 15.8 0.0 1.9 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 CAR24327.1 - 0.0031 17.1 0.2 0.59 9.6 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CAR24327.1 - 0.017 14.1 0.0 0.039 12.9 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CAR24327.1 - 0.08 12.5 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0767 PF15990.5 CAR24327.1 - 1.6 9.0 5.6 2.5 8.3 0.0 3.2 2 1 0 3 3 3 0 UPF0767 family LRR_4 PF12799.7 CAR24328.1 - 2.9e-15 56.1 16.7 7.9e-05 22.9 0.7 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) CAP_GLY PF01302.25 CAR24328.1 - 1.9e-12 47.0 0.1 3.2e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 CAR24328.1 - 1.4e-11 43.9 14.5 7.6e-05 22.4 1.9 4.9 2 2 2 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 CAR24328.1 - 3.5e-08 32.9 10.9 2.6 8.3 0.0 8.1 8 0 0 8 8 8 3 Leucine Rich repeat FNIP PF05725.12 CAR24328.1 - 0.0037 17.4 0.1 0.022 14.9 0.0 2.5 3 1 0 3 3 3 1 FNIP Repeat LRR_1 PF00560.33 CAR24328.1 - 0.02 15.4 23.3 3.2 8.7 0.3 8.3 5 3 0 5 5 5 0 Leucine Rich Repeat Pre-PUA PF17832.1 CAR24329.1 - 3e-26 91.9 1.5 6.6e-26 90.8 1.3 1.6 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 CAR24329.1 - 2e-20 72.5 0.0 3e-20 71.9 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CAR24329.1 - 4.6e-05 23.6 0.8 9.3e-05 22.6 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) Helicase_C PF00271.31 CAR24330.1 - 6.1e-20 71.6 0.2 5.6e-19 68.5 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR24330.1 - 1.9e-19 70.3 0.1 7.6e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR24330.1 - 1e-17 64.5 0.0 8.8e-17 61.4 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase SNF2_N PF00176.23 CAR24330.1 - 7.8e-06 24.8 0.1 3e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 CAR24330.1 - 0.00015 21.5 0.0 0.00051 19.8 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PhoH PF02562.16 CAR24330.1 - 0.0012 18.3 0.3 0.0033 16.9 0.1 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 CAR24330.1 - 0.0073 16.6 0.0 0.084 13.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain Sec3_C PF09763.9 CAR24331.1 - 2.4e-138 462.5 8.2 2.4e-138 462.5 8.2 2.1 2 1 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CAR24331.1 - 4.1e-26 90.9 0.1 1e-25 89.6 0.1 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 CAR24331.1 - 5.6e-08 32.0 1.6 1e-07 31.1 1.6 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C_2 PF15278.6 CAR24331.1 - 0.011 16.0 1.0 0.046 14.0 1.0 2.2 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DnaI_N PF07319.11 CAR24331.1 - 1.4 9.6 4.5 9.2 7.0 0.1 3.7 4 0 0 4 4 4 0 Primosomal protein DnaI N-terminus NTF2 PF02136.20 CAR24332.1 - 7.5e-35 120.1 0.4 8.4e-35 119.9 0.4 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 CAR24332.1 - 0.029 13.5 0.9 0.13 11.4 0.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) DnaJ-X PF14308.6 CAR24334.1 - 5.8e-73 244.8 7.6 5.8e-73 244.8 7.6 2.5 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CAR24334.1 - 5.2e-23 80.9 2.1 5.2e-23 80.9 2.1 3.1 3 0 0 3 3 3 1 DnaJ domain SSP160 PF06933.11 CAR24334.1 - 0.047 11.9 0.4 0.069 11.4 0.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RraA-like PF03737.15 CAR24335.1 - 9.5e-34 116.7 0.0 1.2e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aldolase/RraA ILEI PF15711.5 CAR24335.1 - 0.16 12.4 0.0 2.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Interleukin-like EMT inducer RRM_1 PF00076.22 CAR24336.1 - 4.4e-19 68.1 0.0 6e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR24336.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif EF-hand_4 PF12763.7 CAR24337.1 - 2.5e-25 88.5 0.0 2.3e-13 50.0 0.0 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 CAR24337.1 - 3.9e-15 56.0 264.6 2.3e-05 24.7 15.5 12.5 4 2 7 11 11 11 8 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 CAR24337.1 - 4e-08 33.6 0.2 9e-06 26.1 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CAR24337.1 - 1.2e-06 27.6 0.0 0.0012 18.2 0.0 3.4 3 0 0 3 3 3 1 EF hand KASH_CCD PF14662.6 CAR24337.1 - 2.2e-05 24.4 15.2 0.00019 21.4 1.5 3.2 3 0 0 3 3 3 2 Coiled-coil region of CCDC155 or KASH EF-hand_6 PF13405.6 CAR24337.1 - 3.6e-05 23.3 0.3 0.086 12.8 0.0 3.6 5 0 0 5 5 5 2 EF-hand domain Nefa_Nip30_N PF10187.9 CAR24337.1 - 0.55 10.6 10.0 0.11 12.9 3.5 3.0 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF1664 PF07889.12 CAR24337.1 - 6.3 6.9 6.7 25 4.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Mannosyl_trans3 PF11051.8 CAR24338.1 - 1.1e-68 231.7 0.0 1.4e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative bZIP_2 PF07716.15 CAR24339.1 - 8.5e-09 35.4 5.6 8.5e-09 35.4 5.6 2.8 2 1 1 3 3 3 1 Basic region leucine zipper TSC22 PF01166.18 CAR24339.1 - 0.12 12.7 5.5 0.18 12.2 3.7 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF1843 PF08898.10 CAR24339.1 - 0.27 11.7 3.0 7.7 7.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) LMBR1 PF04791.16 CAR24339.1 - 9.7 5.0 9.0 13 4.5 9.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Proteasome PF00227.26 CAR24341.1 - 1e-57 194.7 0.0 1.3e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR24341.1 - 2.7e-13 49.3 0.2 5.9e-13 48.2 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ANAPC_CDC26 PF10471.9 CAR24341.1 - 0.062 14.1 1.5 0.12 13.2 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 TOM13 PF08219.11 CAR24342.1 - 2.9e-23 81.6 0.0 4.2e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Rpr2 PF04032.16 CAR24343.1 - 1.1e-16 60.9 0.6 1.5e-16 60.4 0.6 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF1173 PF06666.11 CAR24343.1 - 0.079 11.9 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) DUF1746 PF08508.10 CAR24344.1 - 0.0079 16.5 3.4 0.013 15.9 3.4 1.4 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) LETM1 PF07766.13 CAR24345.1 - 3.4e-100 334.8 2.7 3.4e-100 334.8 2.7 1.8 2 1 0 2 2 2 1 LETM1-like protein Ish1 PF10281.9 CAR24345.1 - 0.096 13.0 0.0 0.96 9.8 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SAP PF02037.27 CAR24345.1 - 0.096 12.5 0.3 2.4 8.0 0.0 2.8 2 0 0 2 2 2 0 SAP domain Glyco_hydro_5_C PF18564.1 CAR24346.1 - 9.4e-14 51.7 0.0 2.1e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CAR24346.1 - 3.4e-13 49.7 0.0 2.3e-09 37.1 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_14 PF01373.17 CAR24346.1 - 0.0041 16.1 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 CAR24346.1 - 0.039 13.6 0.1 0.081 12.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DNA_primase_S PF01896.19 CAR24347.1 - 6.7e-66 221.7 0.7 9.4e-66 221.2 0.7 1.2 1 0 0 1 1 1 1 DNA primase small subunit Nyv1_N PF09426.10 CAR24347.1 - 0.039 14.0 0.0 0.089 12.8 0.0 1.6 1 0 0 1 1 1 0 Vacuolar R-SNARE Nyv1 N terminal Proteasome PF00227.26 CAR24348.1 - 7.3e-45 152.8 0.0 8.3e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HA2 PF04408.23 CAR24349.1 - 5.8e-23 81.2 0.7 1.6e-22 79.8 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR24349.1 - 1e-17 64.2 0.0 2.7e-17 62.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR24349.1 - 6e-13 49.1 0.0 2.6e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CAR24349.1 - 2.3e-12 47.0 0.3 5.3e-12 45.9 0.3 1.7 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CAR24349.1 - 5.3e-06 26.8 0.1 1.9e-05 24.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain DEAD PF00270.29 CAR24349.1 - 5.4e-05 23.0 0.3 0.00018 21.4 0.3 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CAR24349.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR24349.1 - 0.0049 17.2 0.1 0.0095 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CAR24349.1 - 0.0071 16.0 0.1 0.02 14.5 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 CAR24349.1 - 0.0071 15.4 0.0 0.02 14.0 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 CAR24349.1 - 0.008 16.7 6.4 0.17 12.4 0.3 3.4 2 2 1 3 3 3 1 ABC transporter AAA_14 PF13173.6 CAR24349.1 - 0.015 15.3 0.1 0.22 11.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 CAR24349.1 - 0.066 13.1 0.1 10 6.1 0.0 3.1 3 0 0 3 3 3 0 Microtubule binding PhoH PF02562.16 CAR24349.1 - 0.074 12.5 0.0 0.26 10.7 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 CAR24349.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Sigma54_activ_2 PF14532.6 CAR24349.1 - 0.16 12.1 0.0 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Amino_oxidase PF01593.24 CAR24350.1 - 6.7e-20 71.8 0.0 8.4e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CAR24350.1 - 3.4e-11 43.2 0.0 7.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAR24350.1 - 6.1e-06 25.6 0.1 1.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CAR24350.1 - 2.8e-05 23.8 0.1 4.4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CAR24350.1 - 0.00047 19.5 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR24350.1 - 0.00053 20.5 0.1 0.0012 19.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CAR24350.1 - 0.0088 15.2 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CAR24350.1 - 0.009 16.0 0.0 0.067 13.2 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.15 CAR24350.1 - 0.015 13.9 0.0 0.026 13.1 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 CAR24350.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Prok-E2_C PF14459.6 CAR24350.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family C AlaDh_PNT_C PF01262.21 CAR24350.1 - 0.17 11.2 0.2 0.31 10.3 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_1 PF00076.22 CAR24351.1 - 1.2e-09 37.8 0.4 2.3e-09 37.0 0.4 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR24351.1 - 1.9e-07 30.7 0.0 2.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CAR24351.1 - 0.007 16.4 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 RNA binding domain RRM_occluded PF16842.5 CAR24351.1 - 0.034 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif YmdB PF13277.6 CAR24351.1 - 0.16 11.3 0.0 0.6 9.4 0.0 1.7 2 0 0 2 2 2 0 YmdB-like protein AMP-binding PF00501.28 CAR24352.1 - 4.4e-73 246.3 0.0 5.6e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GCR1_C PF12550.8 CAR24353.1 - 2.7e-17 62.8 2.0 2.7e-17 62.8 2.0 1.7 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Lzipper-MIP1 PF14389.6 CAR24353.1 - 0.02 15.2 4.7 0.069 13.4 2.2 2.8 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Colicin PF01024.19 CAR24353.1 - 0.022 14.6 0.3 0.11 12.4 0.3 2.0 1 1 0 1 1 1 0 Colicin pore forming domain FlxA PF14282.6 CAR24353.1 - 0.08 12.9 0.4 0.46 10.5 0.6 2.0 2 0 0 2 2 2 0 FlxA-like protein betaPIX_CC PF16523.5 CAR24353.1 - 0.091 12.6 3.3 0.099 12.5 0.4 2.2 2 0 0 2 2 2 0 betaPIX coiled coil USP8_interact PF08941.10 CAR24353.1 - 0.13 12.1 0.1 0.37 10.6 0.2 1.7 2 0 0 2 2 2 0 USP8 interacting SbsC_C PF18058.1 CAR24353.1 - 0.15 12.3 1.0 0.33 11.2 0.0 1.9 2 0 0 2 2 2 0 SbsC C-terminal domain EB1 PF03271.17 CAR24354.1 - 7.7e-16 58.1 0.3 1.9e-15 56.8 0.3 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CAR24354.1 - 1.3e-05 25.3 0.3 2.8e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF499 PF04465.12 CAR24354.1 - 0.0031 15.4 0.1 0.0041 14.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF499) DivIC PF04977.15 CAR24354.1 - 0.031 14.0 2.9 0.063 13.0 2.9 1.4 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.8 CAR24354.1 - 0.036 14.1 1.9 0.066 13.3 1.9 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Hrs_helical PF12210.8 CAR24354.1 - 0.07 13.7 3.1 0.15 12.6 3.1 1.5 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Peptidase_M41 PF01434.18 CAR24355.1 - 2.6e-67 226.4 0.1 3.8e-67 225.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAR24355.1 - 3e-42 144.2 0.0 7.3e-42 142.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR24355.1 - 3.2e-09 36.5 0.1 8.8e-09 35.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CAR24355.1 - 2.9e-07 30.8 0.3 5.9e-07 29.8 0.1 1.7 2 0 0 2 2 1 1 FtsH Extracellular AAA_16 PF13191.6 CAR24355.1 - 0.0013 19.1 0.6 0.062 13.7 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAR24355.1 - 0.0031 17.8 0.2 0.66 10.3 0.1 3.3 4 0 0 4 4 4 1 AAA domain TIP49 PF06068.13 CAR24355.1 - 0.0037 16.5 0.0 0.0079 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CAR24355.1 - 0.0093 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAR24355.1 - 0.013 15.5 0.1 0.054 13.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CAR24355.1 - 0.037 14.4 0.6 0.098 13.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CAR24355.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CARD PF00619.21 CAR24355.1 - 0.087 12.9 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain Cellulase-like PF12876.7 CAR24355.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-binding cellulase-like Mg_chelatase PF01078.21 CAR24355.1 - 0.14 11.5 0.3 0.46 9.8 0.2 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CAR24355.1 - 0.18 12.0 0.0 0.58 10.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAR24355.1 - 0.18 12.3 0.5 1.6 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CAR24355.1 - 0.93 9.8 2.9 24 5.2 0.7 2.6 2 0 0 2 2 2 0 AAA domain HMG_box PF00505.19 CAR24356.1 - 9.4e-16 58.0 4.5 4.5e-15 55.8 4.5 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR24356.1 - 0.0082 16.7 1.9 0.018 15.6 1.9 1.6 1 1 0 1 1 1 1 HMG-box domain Ribosomal_S5 PF00333.20 CAR24357.1 - 2.4e-23 81.9 0.1 4.1e-23 81.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CAR24357.1 - 5.5e-22 77.0 0.0 1.3e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain SURF1 PF02104.15 CAR24358.1 - 2e-43 148.7 0.1 2.9e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 SURF1 family ig PF00047.25 CAR24358.1 - 0.0026 17.9 0.0 0.007 16.5 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin domain Ig_3 PF13927.6 CAR24358.1 - 0.0039 17.8 0.0 0.012 16.2 0.0 1.8 1 0 0 1 1 1 1 Immunoglobulin domain DUF5634 PF18681.1 CAR24358.1 - 0.074 13.4 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5634) DASH_Dam1 PF08653.10 CAR24359.1 - 4.2e-26 90.5 0.7 1.1e-25 89.2 0.7 1.7 1 0 0 1 1 1 1 DASH complex subunit Dam1 DNA_photolyase PF00875.18 CAR24359.1 - 0.022 14.7 0.2 0.047 13.7 0.2 1.5 1 1 0 1 1 1 0 DNA photolyase Ctr PF04145.15 CAR24360.1 - 8.6e-21 75.1 4.2 2.3e-20 73.7 1.7 2.2 2 0 0 2 2 2 1 Ctr copper transporter family B9-C2 PF07162.11 CAR24360.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein DUF4229 PF14012.6 CAR24360.1 - 0.22 11.7 9.5 0.72 10.0 5.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SH2_2 PF14633.6 CAR24361.1 - 3e-69 232.7 2.2 3e-69 232.7 2.2 1.9 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 CAR24361.1 - 3.9e-59 198.7 0.0 1.2e-58 197.2 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CAR24361.1 - 5.9e-44 148.7 0.1 2.2e-43 146.8 0.1 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CAR24361.1 - 2.3e-36 124.7 2.8 3.7e-36 124.0 1.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CAR24361.1 - 2.3e-20 73.0 21.3 2.3e-20 73.0 21.3 5.2 4 1 2 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.24 CAR24361.1 - 1.4e-12 47.5 0.0 4.5e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 CAR24361.1 - 5.3e-05 24.0 0.2 0.00067 20.5 0.2 3.2 1 0 0 1 1 1 1 HHH domain EAP30 PF04157.16 CAR24361.1 - 0.053 12.8 0.0 4.5 6.5 0.0 2.7 2 0 0 2 2 2 0 EAP30/Vps36 family SMK-1 PF04802.15 CAR24361.1 - 0.086 12.7 2.6 2 8.2 0.1 3.4 3 0 0 3 3 3 0 Component of IIS longevity pathway SMK-1 RGS PF00615.19 CAR24361.1 - 0.094 13.0 2.1 0.23 11.7 0.6 2.6 2 0 0 2 2 2 0 Regulator of G protein signaling domain 6PF2K PF01591.18 CAR24362.1 - 4.8e-45 153.6 0.0 3.2e-32 111.6 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase AAA_33 PF13671.6 CAR24362.1 - 3.9e-06 27.1 0.5 0.00012 22.3 0.5 2.4 1 1 0 1 1 1 1 AAA domain LETM1 PF07766.13 CAR24363.1 - 1.1e-93 313.5 3.5 1.1e-93 313.5 3.5 1.4 2 0 0 2 2 2 1 LETM1-like protein Mito_carr PF00153.27 CAR24364.1 - 1e-55 185.6 5.6 1.8e-20 72.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LSM14 PF12701.7 CAR24365.1 - 7.1e-25 86.9 0.1 1.3e-24 86.1 0.1 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CAR24365.1 - 0.00014 22.7 1.8 0.00014 22.7 1.8 3.7 3 1 1 4 4 4 2 FDF domain SM-ATX PF14438.6 CAR24365.1 - 0.00019 21.5 0.3 0.00063 19.8 0.0 2.1 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF269 PF03270.13 CAR24365.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF269 EIIBC-GUT_N PF03612.14 CAR24365.1 - 0.94 9.2 5.9 0.13 12.0 1.0 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 CAR24365.1 - 5.9 6.5 7.1 2.8 7.6 0.4 2.2 2 0 0 2 2 2 0 FAM176 family PAT1 PF09770.9 CAR24365.1 - 6 5.0 30.2 7.7 4.6 30.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hydin_ADK PF17213.3 CAR24365.1 - 6.4 7.0 10.8 0.29 11.4 3.8 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Acetyltransf_1 PF00583.25 CAR24366.1 - 1.3e-06 28.6 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR24366.1 - 2.6e-05 24.2 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR24366.1 - 0.00061 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CAR24366.1 - 0.0024 18.3 0.0 0.0033 17.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CNH PF00780.22 CAR24367.1 - 0.002 17.8 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 CNH domain HTH_IclR PF09339.10 CAR24367.1 - 0.0033 17.2 0.6 0.011 15.5 0.4 2.0 1 1 1 2 2 2 1 IclR helix-turn-helix domain Ribosom_S12_S23 PF00164.25 CAR24368.1 - 2.6e-51 172.1 0.3 3.2e-51 171.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Med26 PF08711.11 CAR24369.1 - 2e-13 50.1 0.2 1.1e-11 44.5 0.0 3.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phasin PF05597.11 CAR24369.1 - 0.37 10.8 6.9 0.039 14.0 1.9 2.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ac76 PF05814.11 CAR24369.1 - 2.7 8.1 3.8 3.6 7.7 0.1 2.7 3 0 0 3 3 3 0 Orf76 (Ac76) Tom5 PF10642.9 CAR24370.1 - 2.5e-22 78.6 0.1 2.7e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 CAR24372.1 - 4.7e-36 124.0 3.3 4.7e-36 124.0 3.3 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CAR24372.1 - 2.7e-29 101.8 166.6 1e-11 45.5 41.5 4.7 1 1 3 4 4 4 4 Nucleoporin FG repeat region COG2 PF06148.11 CAR24373.1 - 3.6e-08 33.6 4.2 3.6e-08 33.6 4.2 1.7 1 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 TssO PF17561.2 CAR24373.1 - 0.012 15.7 0.5 0.031 14.4 0.2 1.8 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF883 PF05957.13 CAR24373.1 - 0.018 15.6 3.2 0.51 11.0 0.6 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) T2SSF PF00482.23 CAR24373.1 - 0.054 13.5 0.5 0.41 10.6 0.0 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Syntaxin_2 PF14523.6 CAR24373.1 - 0.081 13.3 9.9 2.1 8.7 0.6 3.3 1 1 2 3 3 3 0 Syntaxin-like protein Focal_AT PF03623.13 CAR24373.1 - 0.11 12.5 3.4 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region Apolipoprotein PF01442.18 CAR24373.1 - 0.12 12.2 2.7 0.29 11.0 2.7 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PqqD PF05402.12 CAR24373.1 - 0.18 12.1 1.0 4.7 7.6 0.0 3.2 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) YlqD PF11068.8 CAR24373.1 - 0.27 11.6 2.7 0.41 11.0 0.4 2.1 2 0 0 2 2 2 0 YlqD protein DUF1664 PF07889.12 CAR24373.1 - 1.6 8.8 4.4 18 5.4 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PCRF PF03462.18 CAR24373.1 - 2.6 7.9 4.7 11 5.9 0.6 2.1 1 1 1 2 2 2 0 PCRF domain Synaptonemal_3 PF15191.6 CAR24373.1 - 3.8 7.4 9.7 2 8.2 0.5 3.2 1 1 1 3 3 3 0 Synaptonemal complex central element protein 3 Mcl1_mid PF12341.8 CAR24374.1 - 6.2e-79 265.4 0.0 1.5e-78 264.2 0.0 1.6 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CAR24374.1 - 1.4e-08 34.9 0.0 0.27 11.6 0.0 4.1 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CAR24374.1 - 0.045 13.3 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain DNA_pol_alpha_N PF12254.8 CAR24374.1 - 0.052 13.6 4.2 0.13 12.3 4.2 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40_like PF17005.5 CAR24374.1 - 0.14 11.5 0.0 2.2 7.5 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 CAR24375.1 - 2.5e-18 66.1 1.0 9.4e-05 23.1 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 CAR24375.1 - 0.016 14.5 0.0 2.2 7.5 0.0 2.6 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 CAR24375.1 - 0.047 12.2 0.1 0.66 8.4 0.0 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 CAR24375.1 - 0.14 12.4 0.0 4.7 7.6 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ammonium_transp PF00909.21 CAR24376.1 - 3e-116 388.4 22.3 3.4e-116 388.2 22.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ABC2_membrane_2 PF12679.7 CAR24376.1 - 0.095 12.0 1.0 0.27 10.5 1.0 1.8 1 0 0 1 1 1 0 ABC-2 family transporter protein Phage_holin_2_1 PF04971.12 CAR24376.1 - 1.3 9.1 6.2 0.37 10.8 0.2 3.0 3 0 0 3 3 3 0 Bacteriophage P21 holin S DUF5355 PF17306.2 CAR24377.1 - 1.1e-71 241.5 0.4 1.3e-71 241.3 0.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5355) BRO1 PF03097.18 CAR24377.1 - 3.8e-05 22.7 0.1 5.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 BRO1-like domain Acyltransferase PF01553.21 CAR24378.1 - 3.5e-05 23.4 0.0 6.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 CAR24379.1 - 3.7e-14 52.5 0.0 6.9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.23 CAR24380.1 - 1.5e-99 333.1 3.7 1.5e-99 333.1 3.7 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAR24380.1 - 9.3e-56 187.9 0.4 9.3e-56 187.9 0.4 2.6 2 1 0 2 2 2 1 Microtubule binding Ribosomal_L29 PF00831.23 CAR24380.1 - 0.00028 20.8 1.9 0.00028 20.8 1.9 4.1 5 0 0 5 5 5 1 Ribosomal L29 protein DUF743 PF05332.11 CAR24380.1 - 0.37 10.9 2.9 0.47 10.5 0.1 2.4 1 1 1 3 3 3 0 Protein of unknown function (DUF743) PKcGMP_CC PF16808.5 CAR24380.1 - 5.1 7.0 10.0 2.7 7.9 0.5 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Rrp15p PF07890.12 CAR24381.1 - 4.7e-32 111.1 14.8 4.7e-32 111.1 14.8 2.3 2 1 0 2 2 2 1 Rrp15p Ndc1_Nup PF09531.10 CAR24381.1 - 3.7 6.1 6.2 4.7 5.8 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Metallophos PF00149.28 CAR24382.1 - 1.3e-31 110.7 0.1 2.1e-31 110.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CAR24382.1 - 1.7e-21 76.3 0.6 4.7e-21 74.9 0.1 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CAR24382.1 - 1.4e-18 65.9 1.0 1.6e-07 30.8 0.7 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR24382.1 - 1.9e-14 52.5 0.2 6.6e-05 22.7 0.5 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAR24382.1 - 1.3e-08 34.4 0.0 3.8e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_9 PF13371.6 CAR24382.1 - 3.5e-06 27.1 0.0 1.2e-05 25.3 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR24382.1 - 2.2e-05 24.3 4.7 0.022 14.9 0.2 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR24382.1 - 0.00037 20.7 0.1 1.9 9.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR24382.1 - 0.0011 18.9 1.0 0.18 11.9 0.1 3.0 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 CAR24382.1 - 0.0073 16.6 0.0 0.99 9.7 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 CAR24382.1 - 0.023 14.8 1.6 0.06 13.4 1.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 CAR24382.1 - 0.13 12.3 0.0 0.63 10.2 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CAR24382.1 - 0.14 11.6 0.8 14 5.2 0.1 2.9 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 CAR24382.1 - 0.16 12.7 0.1 16 6.4 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat CBF PF03914.17 CAR24383.1 - 4.8e-36 124.3 1.1 4.8e-36 124.3 1.1 1.9 2 0 0 2 2 2 1 CBF/Mak21 family Asn_synthase PF00733.21 CAR24384.1 - 1.8e-94 317.4 0.8 3.9e-54 184.7 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CAR24384.1 - 5.1e-36 123.3 0.0 8.1e-36 122.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CAR24384.1 - 8.3e-30 103.7 0.0 1.7e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CAR24384.1 - 4.1e-06 26.4 0.0 7.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CAR24384.1 - 0.017 14.2 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Sulfate_transp PF00916.20 CAR24386.1 - 8.9e-75 251.8 22.8 1.3e-74 251.2 22.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CAR24386.1 - 8.7e-13 47.9 1.3 1.9e-12 46.9 1.3 1.6 1 0 0 1 1 1 1 STAS domain Phage_holin_Dp1 PF16938.5 CAR24386.1 - 2.9 8.2 5.9 4.2 7.7 1.3 2.8 2 0 0 2 2 2 0 Putative phage holin Dp-1 Oleosin PF01277.17 CAR24386.1 - 3 7.6 7.0 0.67 9.7 2.3 2.5 2 0 0 2 2 2 0 Oleosin DUF2608 PF11019.8 CAR24387.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) TANGO2 PF05742.12 CAR24388.1 - 1.3e-57 195.7 0.0 1.5e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 LIDHydrolase PF10230.9 CAR24389.1 - 4.9e-69 232.8 0.1 5.6e-69 232.7 0.1 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF1057 PF06342.12 CAR24389.1 - 0.00061 18.9 0.0 0.076 12.0 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 CAR24389.1 - 0.0017 18.1 0.8 0.0024 17.6 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CAR24389.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CAR24389.1 - 0.0032 16.8 0.0 0.0059 15.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 CAR24389.1 - 0.007 15.9 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 CAR24389.1 - 0.0085 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 CAR24389.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_6 PF12697.7 CAR24389.1 - 0.022 15.4 0.0 0.025 15.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.10 CAR24389.1 - 0.073 12.1 0.1 0.36 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Utp8 PF10395.9 CAR24390.1 - 3.9e-219 729.6 22.4 4.7e-219 729.4 22.4 1.1 1 0 0 1 1 1 1 Utp8 family CAMSAP_CH PF11971.8 CAR24390.1 - 0.025 14.4 0.1 0.19 11.6 0.0 2.5 2 0 0 2 2 2 0 CAMSAP CH domain SYF2 PF08231.12 CAR24391.1 - 5.8e-09 36.5 17.4 5.8e-09 36.5 17.4 2.2 1 1 1 2 2 2 1 SYF2 splicing factor Transketolase_C PF02780.20 CAR24391.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Transketolase, C-terminal domain BAR_2 PF10455.9 CAR24392.1 - 5.9e-99 330.8 19.6 9.1e-99 330.2 19.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CAR24392.1 - 1.8e-10 40.9 18.2 1.5e-07 31.3 14.2 2.9 2 1 0 2 2 2 2 BAR domain Herpes_UL6 PF01763.16 CAR24392.1 - 0.0056 15.3 6.9 0.009 14.6 6.9 1.3 1 0 0 1 1 1 1 Herpesvirus UL6 like Virulence_fact PF13769.6 CAR24392.1 - 0.087 13.1 0.2 0.087 13.1 0.2 2.7 2 1 1 3 3 3 0 Virulence factor DUF4834 PF16118.5 CAR24392.1 - 1.6 9.8 7.4 2.3 9.3 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DASH_Dam1 PF08653.10 CAR24393.1 - 2.4 8.0 3.7 27 4.7 0.5 3.0 2 0 0 2 2 2 0 DASH complex subunit Dam1 MARVEL PF01284.23 CAR24394.1 - 4e-29 101.5 13.1 5.5e-29 101.1 13.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain Band_7 PF01145.25 CAR24395.1 - 1.4e-22 80.6 6.4 2.8e-22 79.6 6.4 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CAR24395.1 - 0.00081 18.5 2.3 0.001 18.2 2.3 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial UQ_con PF00179.26 CAR24396.1 - 3.2e-35 120.8 0.0 3.5e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 CAR24396.1 - 0.0063 16.2 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 CAR24396.1 - 0.0099 16.2 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Ribonuc_L-PSP PF01042.21 CAR24397.1 - 1.7e-23 82.9 0.0 2.2e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4817 PF16087.5 CAR24397.1 - 0.013 15.3 0.0 0.06 13.2 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain (DUF4817) Pet20 PF08692.10 CAR24398.1 - 1.6e-47 161.5 0.0 2.2e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Ribosomal_60s PF00428.19 CAR24398.1 - 0.52 10.9 3.4 0.85 10.3 3.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Actin PF00022.19 CAR24399.1 - 3.9e-22 78.4 0.0 1.3e-15 56.9 0.0 3.7 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 CAR24399.1 - 1.7e-06 27.5 0.6 0.024 13.9 0.0 2.4 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 CAR24399.1 - 1.3e-05 24.2 0.0 0.00021 20.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CAR24399.1 - 0.00057 20.3 0.3 0.0019 18.6 0.2 1.9 2 0 0 2 2 2 1 Cell division protein FtsA GAIN_A PF18619.1 CAR24399.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Seryl_tRNA_N PF02403.22 CAR24399.1 - 0.14 12.4 2.1 0.93 9.8 1.1 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain MutL PF13941.6 CAR24399.1 - 0.36 9.4 1.5 1 7.9 0.3 2.0 2 0 0 2 2 2 0 MutL protein HSF_DNA-bind PF00447.17 CAR24400.1 - 4.4e-29 100.9 0.4 4.4e-29 100.9 0.4 2.5 2 0 0 2 2 2 1 HSF-type DNA-binding Trypan_PARP PF05887.11 CAR24400.1 - 0.0063 16.5 3.5 0.026 14.5 3.5 2.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) UBA PF00627.31 CAR24401.1 - 9.8e-07 28.6 0.1 3e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CAR24401.1 - 0.0015 18.3 0.0 0.0069 16.2 0.0 2.3 1 0 0 1 1 1 1 UBA-like domain HBS1_N PF08938.10 CAR24401.1 - 0.03 14.6 0.6 1.8 8.9 0.0 3.5 4 0 0 4 4 4 0 HBS1 N-terminus CUE PF02845.16 CAR24401.1 - 0.047 13.4 0.1 0.28 10.9 0.1 2.4 1 1 0 1 1 1 0 CUE domain YfhO PF09586.10 CAR24401.1 - 0.15 10.2 0.4 0.2 9.9 0.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Metallophos PF00149.28 CAR24402.1 - 5.2e-12 46.7 0.2 1.5e-10 41.9 0.0 2.8 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase Iso_dh PF00180.20 CAR24403.1 - 4.8e-104 348.2 0.0 5.6e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Baculo_RING PF05883.11 CAR24403.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain ThiF PF00899.21 CAR24404.1 - 6.6e-69 232.0 0.0 8.8e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CAR24404.1 - 2.6e-09 37.4 1.0 5.4e-05 23.2 0.2 2.6 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 CAR24404.1 - 8.9e-05 23.0 0.2 0.00028 21.4 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 CAR24404.1 - 0.0011 19.1 0.6 0.0034 17.4 0.1 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thioredoxin_8 PF13905.6 CAR24404.1 - 0.016 15.5 0.2 0.041 14.2 0.2 1.7 1 0 0 1 1 1 0 Thioredoxin-like NAD_binding_7 PF13241.6 CAR24404.1 - 0.019 15.4 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding RhoGAP PF00620.27 CAR24405.1 - 1.6e-34 118.9 0.7 4.3e-34 117.5 0.7 1.7 1 1 0 1 1 1 1 RhoGAP domain BAR PF03114.18 CAR24406.1 - 4.8e-62 209.7 8.2 6.2e-62 209.4 8.2 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CAR24406.1 - 5.9e-15 54.6 0.1 1.3e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR24406.1 - 1.1e-11 44.4 0.4 1.9e-11 43.6 0.4 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR24406.1 - 3.7e-07 29.7 0.0 7.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Sugar_tr PF00083.24 CAR24407.1 - 1.8e-91 307.3 24.5 2.1e-48 165.3 4.8 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAR24407.1 - 1.3e-26 93.4 22.1 1.3e-26 93.4 22.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CAR24407.1 - 3.3 6.0 14.7 0.15 10.4 6.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector ERCC4 PF02732.15 CAR24408.1 - 2.8e-23 82.8 0.8 5.3e-23 82.0 0.8 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 CAR24408.1 - 0.017 15.4 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain RepB-RCR_reg PF10723.9 CAR24408.1 - 0.054 13.4 0.0 0.31 11.0 0.0 2.3 1 0 0 1 1 1 0 Replication regulatory protein RepB HTH_50 PF18024.1 CAR24408.1 - 0.17 11.5 0.8 0.38 10.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain GTP_EFTU PF00009.27 CAR24409.1 - 2.2e-67 226.4 0.3 3.1e-67 225.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CAR24409.1 - 3.9e-33 113.8 0.0 2.4e-32 111.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CAR24409.1 - 1e-21 76.7 0.0 2.7e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR24409.1 - 3.3e-13 49.8 0.0 1e-12 48.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CAR24409.1 - 7e-13 48.5 0.0 2.2e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CAR24409.1 - 9.8e-05 22.4 0.4 0.0002 21.4 0.4 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PX PF00787.24 CAR24410.1 - 1.2e-08 34.9 0.2 2.4e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CAR24410.1 - 2.6e-05 23.9 8.3 3.9e-05 23.3 8.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like HAD_2 PF13419.6 CAR24411.1 - 4.1e-17 62.8 0.0 1.8e-16 60.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR24411.1 - 1e-14 55.3 0.0 7.9e-11 42.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR24411.1 - 1.6e-10 40.9 0.0 4.3e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 CAR24411.1 - 5.7e-05 23.6 0.0 0.0002 21.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAR24411.1 - 0.023 14.4 0.1 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAR24411.1 - 0.17 11.4 0.0 0.44 10.0 0.0 1.7 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Gpr1_Fun34_YaaH PF01184.19 CAR24413.1 - 4.4e-80 268.1 17.9 5.1e-80 267.9 17.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2344 PF10105.9 CAR24413.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) FTA4 PF13093.6 CAR24415.1 - 4.7e-05 23.4 3.0 6.3e-05 23.0 3.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF745 PF05335.13 CAR24415.1 - 0.0099 15.6 6.1 0.65 9.7 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF745) Ribosomal_60s PF00428.19 CAR24416.1 - 3.5e-25 88.4 15.9 4e-25 88.2 15.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Mito_carr PF00153.27 CAR24417.1 - 8.7e-60 198.7 2.2 5.7e-21 74.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CAR24417.1 - 0.0046 17.3 0.4 0.12 12.7 0.4 2.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 CAR24418.1 - 9.2e-50 166.5 4.1 1.1e-17 63.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Herpes_gE PF02480.16 CAR24419.1 - 0.048 12.4 0.0 0.054 12.2 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Phage_SSB PF16773.5 CAR24419.1 - 0.093 12.8 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Lactococcus phage single-stranded DNA binding protein CUB_2 PF02408.20 CAR24419.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.1 1 0 0 1 1 1 0 CUB-like domain RRM_1 PF00076.22 CAR24420.1 - 2e-12 46.7 0.1 4.9e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CAR24420.1 - 0.0027 18.2 0.8 0.0027 18.2 0.8 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DUF1580 PF07618.11 CAR24420.1 - 0.17 11.5 1.0 0.72 9.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1580) SPA PF08616.10 CAR24421.1 - 1.1e-33 115.6 0.1 2.7e-33 114.3 0.1 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CAR24421.1 - 7.8e-30 104.1 1.4 9.9e-30 103.7 0.1 1.9 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking TPP_enzyme_N PF02776.18 CAR24422.1 - 1.3e-25 90.0 0.0 2.1e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR24422.1 - 3.3e-15 56.0 0.0 6.8e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR24422.1 - 3.6e-12 46.3 0.0 8.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AIRC PF00731.20 CAR24423.1 - 2.2e-63 212.2 0.5 4.4e-63 211.3 0.5 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 CAR24423.1 - 3.3e-61 205.8 0.0 5.5e-61 205.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CAR24423.1 - 2.3e-19 68.8 0.0 4.5e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 CAR24423.1 - 0.00021 20.7 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CAR24423.1 - 0.00036 19.9 0.0 0.00079 18.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_D2 PF02786.17 CAR24423.1 - 0.00072 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain F420_oxidored PF03807.17 CAR24423.1 - 0.04 14.5 0.0 0.14 12.8 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NPV_P10 PF05531.12 CAR24423.1 - 0.042 14.3 0.2 0.13 12.8 0.2 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Dala_Dala_lig_C PF07478.13 CAR24423.1 - 0.047 13.2 0.0 0.29 10.6 0.0 2.1 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus NAD_binding_10 PF13460.6 CAR24423.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_transf_21 PF13506.6 CAR24424.1 - 9.6e-18 64.2 0.0 9.5e-13 48.0 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CAR24424.1 - 1.1e-12 48.4 0.0 1e-10 41.9 0.0 2.5 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CAR24424.1 - 0.00044 20.1 0.0 0.0014 18.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Complex1_LYR PF05347.15 CAR24425.1 - 2.8e-16 59.3 0.6 3.2e-16 59.1 0.6 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CAR24425.1 - 0.0016 19.2 0.4 0.0018 19.0 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CAR24425.1 - 0.004 17.7 0.1 0.0052 17.4 0.1 1.2 1 1 0 1 1 1 1 Complex1_LYR-like Topoisom_I_N PF02919.15 CAR24425.1 - 0.037 13.5 0.0 0.042 13.3 0.0 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RhoGAP PF00620.27 CAR24426.1 - 1.1e-41 142.2 0.5 1.1e-41 142.2 0.5 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CAR24426.1 - 2.7e-11 43.5 25.0 2e-05 24.7 5.6 2.7 2 0 0 2 2 2 2 LIM domain Carbpep_Y_N PF05388.11 CAR24426.1 - 0.041 14.4 3.3 0.17 12.4 2.3 2.5 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Spc7 PF08317.11 CAR24426.1 - 0.19 10.6 10.8 0.061 12.2 6.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CAR24426.1 - 0.46 10.7 12.3 0.04 14.1 4.5 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 CAR24426.1 - 2.3 8.5 8.5 0.16 12.2 2.0 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper LSM PF01423.22 CAR24427.1 - 3.3e-17 61.9 0.1 3.9e-17 61.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR24427.1 - 4.2e-06 26.8 0.0 5.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CAR24427.1 - 0.0024 17.9 0.1 0.0028 17.7 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain Tudor_2 PF18104.1 CAR24427.1 - 0.05 13.3 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain DUF2642 PF10842.8 CAR24427.1 - 0.082 12.8 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Hfq PF17209.3 CAR24427.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Hfq protein F1F0-ATPsyn_F PF10791.9 CAR24428.1 - 8.8e-42 141.5 0.2 9.9e-42 141.3 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Pyr_redox_2 PF07992.14 CAR24429.1 - 2.6e-08 33.4 0.0 7.1e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR24429.1 - 0.00048 20.3 0.0 0.0015 18.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CAR24429.1 - 0.0019 18.2 0.0 0.0074 16.3 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lipase_GDSL_2 PF13472.6 CAR24430.1 - 4.8e-24 85.7 0.0 6.7e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CAR24430.1 - 4.6e-13 49.6 0.0 7.2e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF3253 PF11625.8 CAR24430.1 - 0.059 13.6 0.0 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) BCS1_N PF08740.11 CAR24432.1 - 6e-45 153.5 0.0 7.9e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CAR24432.1 - 2.6e-23 82.9 0.0 4.7e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAR24432.1 - 0.00048 19.9 0.0 0.00085 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CAR24432.1 - 0.0013 18.0 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CAR24432.1 - 0.0015 18.5 0.0 0.0046 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR24432.1 - 0.0018 18.7 0.0 0.0069 16.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CAR24432.1 - 0.0027 17.2 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CAR24432.1 - 0.0048 17.5 0.0 0.01 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAR24432.1 - 0.0096 16.1 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CAR24432.1 - 0.011 15.7 0.0 0.083 12.8 0.0 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 CAR24432.1 - 0.017 15.6 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CAR24432.1 - 0.019 14.7 0.0 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CAR24432.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR24432.1 - 0.023 14.4 0.0 0.094 12.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase PF06745.13 CAR24432.1 - 0.036 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.22 CAR24432.1 - 0.041 14.3 0.0 0.086 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CAR24432.1 - 0.044 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.21 CAR24432.1 - 0.071 13.1 1.1 0.14 12.1 1.1 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif AAA_25 PF13481.6 CAR24432.1 - 0.076 12.6 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR24432.1 - 0.096 12.6 0.0 0.31 10.9 0.0 1.9 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 CAR24432.1 - 0.12 12.3 0.0 0.31 11.1 0.0 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CAR24432.1 - 0.13 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CAR24432.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CAR24432.1 - 0.21 12.0 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain YTH PF04146.15 CAR24433.1 - 3.6e-37 127.9 0.4 1.6e-36 125.8 0.4 1.9 1 1 0 1 1 1 1 YT521-B-like domain COQ7 PF03232.13 CAR24434.1 - 1.8e-74 249.2 0.1 2.2e-74 248.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CAR24434.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.6 2 0 0 2 2 2 0 Rubrerythrin EF-hand_1 PF00036.32 CAR24435.1 - 4.3e-26 88.5 2.0 1.8e-07 30.2 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CAR24435.1 - 9e-24 83.7 3.6 1e-15 57.9 0.2 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR24435.1 - 2.7e-22 76.7 1.4 3e-05 23.6 0.1 4.9 6 0 0 6 6 5 3 EF-hand domain EF-hand_5 PF13202.6 CAR24435.1 - 1.1e-18 65.8 2.2 1.8e-06 27.2 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CAR24435.1 - 5.4e-17 61.4 3.3 1.9e-08 34.0 0.1 3.6 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 CAR24435.1 - 1.3e-05 25.1 1.8 1 9.3 0.1 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAR24435.1 - 5.8e-05 23.4 0.6 0.22 11.9 0.1 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CAR24435.1 - 0.00012 22.4 0.1 0.016 15.6 0.0 2.8 1 1 1 2 2 2 1 EF-hand domain S10_plectin PF03501.15 CAR24435.1 - 0.0038 17.3 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain SHOCT PF09851.9 CAR24435.1 - 0.021 14.6 3.1 2.4 8.0 0.1 2.7 2 0 0 2 2 2 0 Short C-terminal domain PMBR PF09373.10 CAR24435.1 - 0.022 14.9 0.4 58 4.1 0.0 4.0 4 0 0 4 4 4 0 Pseudomurein-binding repeat EF-hand_14 PF17959.1 CAR24435.1 - 0.022 15.1 0.8 2.3 8.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_2 PF09068.11 CAR24435.1 - 0.089 12.9 0.0 7.6 6.7 0.0 2.5 2 1 0 2 2 2 0 EF hand TAFH PF07531.14 CAR24435.1 - 0.093 12.8 0.1 43 4.3 0.0 3.2 2 1 1 3 3 3 0 NHR1 homology to TAF UCH PF00443.29 CAR24438.1 - 4e-54 183.8 2.3 3.1e-53 180.9 0.4 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CAR24438.1 - 3.8e-46 154.8 6.7 1.7e-15 56.6 0.1 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 CAR24438.1 - 1.5e-05 24.7 2.2 0.0022 17.7 0.5 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BA14K PF07886.11 CAR24438.1 - 3 7.8 4.5 6.6 6.7 4.5 1.5 1 0 0 1 1 1 0 BA14K-like protein GPP34 PF05719.11 CAR24439.1 - 3e-68 229.9 0.0 4e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.28 CAR24440.1 - 2.4e-64 218.0 1.3 3.4e-64 217.5 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Leo1 PF04004.13 CAR24441.1 - 3.7e-47 160.2 1.1 3.7e-47 160.2 1.1 2.1 2 0 0 2 2 2 1 Leo1-like protein Profilin PF00235.19 CAR24442.1 - 9.2e-46 155.2 0.0 1e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Profilin YCII PF03795.14 CAR24443.1 - 1.4e-06 28.6 0.0 1.6e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain RAI1 PF08652.11 CAR24444.1 - 4.9e-05 23.4 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Mor PF08765.11 CAR24444.1 - 0.036 14.1 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Mor transcription activator family Bac_surface_Ag PF01103.23 CAR24445.1 - 4.9e-26 92.0 5.0 6.1e-26 91.7 5.0 1.1 1 0 0 1 1 1 1 Surface antigen NIBRIN_BRCT_II PF16508.5 CAR24446.1 - 2.5e-05 24.6 0.3 0.00012 22.4 0.0 2.2 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 CAR24446.1 - 0.00024 21.4 0.3 0.0017 18.7 0.0 2.5 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 CAR24446.1 - 0.0049 17.2 1.0 0.04 14.2 0.1 2.9 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DUF848 PF05852.11 CAR24446.1 - 0.015 15.4 3.5 0.045 13.9 1.8 2.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FHA_2 PF17913.1 CAR24446.1 - 0.051 13.8 1.5 0.15 12.3 0.3 2.4 2 0 0 2 2 2 0 FHA domain Aldo_ket_red PF00248.21 CAR24447.1 - 9.2e-40 136.7 0.0 1.1e-37 129.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Kei1 PF08552.11 CAR24448.1 - 4e-38 131.2 6.2 5.5e-38 130.8 6.2 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF3611 PF12263.8 CAR24448.1 - 1.8 8.4 10.1 1 9.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) RIO1 PF01163.22 CAR24449.1 - 3.7e-71 238.6 0.9 3.7e-71 238.6 0.9 2.6 3 0 0 3 3 3 1 RIO1 family CDC45 PF02724.14 CAR24449.1 - 0.00035 19.0 12.6 0.00048 18.6 12.6 1.4 1 0 0 1 1 1 1 CDC45-like protein APH PF01636.23 CAR24449.1 - 0.06 13.3 0.1 1.9 8.3 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF2151 PF10221.9 CAR24449.1 - 0.63 8.6 0.0 0.63 8.6 0.0 2.5 3 0 0 3 3 3 0 Cell cycle and development regulator TLD PF07534.16 CAR24450.1 - 3.9e-25 88.7 0.0 1.4e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 TLD NRN1 PF15056.6 CAR24450.1 - 0.0072 16.4 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Neuritin protein family NUC153 PF08159.12 CAR24451.1 - 7.7e-14 51.2 1.7 7.7e-14 51.2 1.7 3.3 3 1 1 4 4 4 1 NUC153 domain WD40 PF00400.32 CAR24452.1 - 4.6e-28 96.9 5.0 3.9e-05 24.3 0.0 5.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR24452.1 - 9.9e-11 41.8 0.0 0.0013 18.9 0.0 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1797 PF08796.10 CAR24452.1 - 0.14 12.2 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) AAA PF00004.29 CAR24453.1 - 5.5e-41 140.1 0.1 1.4e-40 138.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CAR24453.1 - 1.4e-18 66.6 0.2 2.8e-18 65.6 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CAR24453.1 - 2.9e-08 33.4 0.1 1.2e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CAR24453.1 - 1.9e-05 25.1 0.1 0.017 15.5 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CAR24453.1 - 2.3e-05 24.6 0.2 0.0002 21.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAR24453.1 - 5.8e-05 23.1 0.1 0.00039 20.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR24453.1 - 0.00077 19.8 0.3 0.078 13.3 0.0 2.7 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CAR24453.1 - 0.00085 19.1 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CAR24453.1 - 0.0038 17.4 0.1 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CAR24453.1 - 0.0047 16.4 0.2 0.033 13.6 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 CAR24453.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CAR24453.1 - 0.011 15.2 0.2 0.033 13.6 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAR24453.1 - 0.023 14.5 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CAR24453.1 - 0.04 13.7 0.9 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAR24453.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region TolA_bind_tri PF16331.5 CAR24453.1 - 0.054 13.6 4.4 0.12 12.4 2.3 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation AAA_24 PF13479.6 CAR24453.1 - 0.1 12.3 0.5 0.31 10.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CAR24453.1 - 0.13 11.6 1.1 0.32 10.3 0.0 2.1 3 0 0 3 3 3 0 KaiC Fez1 PF06818.15 CAR24453.1 - 5.2 7.5 7.4 2.3 8.6 2.9 2.3 2 1 0 2 2 2 0 Fez1 RNA_pol_Rpb1_1 PF04997.12 CAR24454.1 - 2.9e-81 273.2 0.0 7.9e-81 271.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CAR24454.1 - 7.5e-81 271.5 0.1 1.1e-80 270.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CAR24454.1 - 4.6e-76 254.7 0.0 8.8e-76 253.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CAR24454.1 - 9.3e-38 129.6 0.0 2.4e-37 128.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CAR24454.1 - 3.3e-31 107.4 0.0 7.9e-31 106.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rad60-SLD PF11976.8 CAR24455.1 - 1e-19 70.1 0.6 1e-19 70.1 0.6 3.2 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CAR24455.1 - 1e-09 38.0 2.3 6.2e-09 35.5 0.1 2.8 2 0 0 2 2 2 1 Ubiquitin family Rhamno_transf PF11316.8 CAR24455.1 - 0.03 13.7 0.2 0.066 12.6 0.2 1.5 1 0 0 1 1 1 0 Putative rhamnosyl transferase TBK1_ULD PF18396.1 CAR24455.1 - 0.12 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Peptidase_M18 PF02127.15 CAR24456.1 - 3.6e-176 586.2 0.0 4.1e-176 586.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CAR24456.1 - 7.6e-09 35.0 0.0 3.7e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 M42 glutamyl aminopeptidase WD40 PF00400.32 CAR24457.1 - 0.00099 19.9 0.2 1.6 9.7 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Pox_Ag35 PF03286.14 CAR24457.1 - 2.9 7.6 6.7 2.6 7.8 5.5 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein ThiF PF00899.21 CAR24458.1 - 1e-56 192.0 0.0 1.5e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CAR24458.1 - 1.2e-09 38.6 0.0 2.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 CAR24458.1 - 0.002 18.2 0.1 0.0077 16.3 0.0 2.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CAR24458.1 - 0.081 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Myc-LZ PF02344.15 CAR24458.1 - 0.16 12.1 4.1 0.47 10.6 2.5 2.2 2 0 0 2 2 2 0 Myc leucine zipper domain EMP24_GP25L PF01105.24 CAR24459.1 - 7.5e-32 110.7 0.6 8.7e-32 110.5 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.6 CAR24459.1 - 0.091 13.2 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) BCIP PF13862.6 CAR24461.1 - 9.1e-46 156.2 0.5 1.2e-45 155.9 0.5 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein HSA PF07529.13 CAR24462.1 - 8.6e-13 48.4 0.0 8.6e-13 48.4 0.0 3.1 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 CAR24462.1 - 5.7e-09 36.1 0.8 1.7e-08 34.6 0.8 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CAR24462.1 - 0.017 15.3 0.7 0.042 14.1 0.1 2.1 2 0 0 2 2 2 0 Myb-like DNA-binding domain SUIM_assoc PF16619.5 CAR24462.1 - 2.6 8.2 15.1 1.5 8.9 9.7 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 VHS PF00790.19 CAR24463.1 - 7.6e-45 152.2 0.1 3.2e-44 150.2 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 CAR24463.1 - 1.9e-23 82.9 1.3 4.5e-23 81.7 0.2 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 CAR24463.1 - 9.4e-19 67.5 1.1 9.4e-19 67.5 1.1 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 CAR24463.1 - 2.7e-06 26.9 0.6 7.8e-06 25.4 0.2 2.0 1 1 0 1 1 1 1 GGA N-GAT domain CbtA_toxin PF06755.12 CAR24463.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system BORCS6 PF10157.9 CAR24464.1 - 0.00046 20.5 0.1 0.0006 20.1 0.1 1.2 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 UPF0184 PF03670.13 CAR24464.1 - 0.045 14.1 2.5 0.11 13.0 0.5 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) Dysbindin PF04440.16 CAR24464.1 - 0.097 12.8 0.2 0.16 12.1 0.2 1.3 1 0 0 1 1 1 0 Dysbindin (Dystrobrevin binding protein 1) Spc110_C PF18520.1 CAR24465.1 - 7.1e-25 86.4 7.4 9.6e-25 86.0 1.9 3.5 2 0 0 2 2 2 1 Spindle pole body component 110 C-terminal domain Cnn_1N PF07989.11 CAR24465.1 - 0.00026 21.1 6.0 0.00026 21.1 6.0 10.0 2 1 5 7 7 7 2 Centrosomin N-terminal motif 1 WD40_alt PF14077.6 CAR24465.1 - 0.0043 16.9 3.8 1.3 8.9 0.7 3.6 2 0 0 2 2 2 2 Alternative WD40 repeat motif Glycos_transf_3 PF00591.21 CAR24466.1 - 6.8e-82 274.9 0.0 8.3e-82 274.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CAR24466.1 - 3.7e-09 36.3 0.0 7.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Septin PF00735.18 CAR24467.1 - 2.6e-115 384.5 0.0 4.1e-115 383.9 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAR24467.1 - 5e-07 29.8 0.0 9.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CAR24467.1 - 0.00029 21.1 0.0 0.00074 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 CAR24467.1 - 0.00037 20.1 0.2 0.011 15.2 0.0 2.6 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR24467.1 - 0.00048 20.1 0.2 0.00048 20.1 0.2 2.7 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 CAR24467.1 - 0.0069 16.5 4.4 4.2 7.4 0.0 3.2 2 1 1 3 3 3 1 Dynamin family AIG1 PF04548.16 CAR24467.1 - 0.009 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 CAR24467.1 - 0.0095 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 CAR24467.1 - 0.01 16.0 0.3 0.024 14.8 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CAR24467.1 - 0.012 15.4 0.2 0.05 13.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAR24467.1 - 0.02 15.3 0.0 0.057 13.8 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 CAR24467.1 - 0.02 15.3 0.0 0.048 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IIGP PF05049.13 CAR24467.1 - 0.037 13.1 0.2 0.11 11.5 0.2 1.8 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NACHT PF05729.12 CAR24467.1 - 0.044 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 CAR24467.1 - 0.044 13.2 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.27 CAR24467.1 - 0.054 14.0 0.1 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter PGBA_C PF15437.6 CAR24467.1 - 0.13 12.6 2.4 0.31 11.4 2.4 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Pyr_redox_2 PF07992.14 CAR24468.1 - 2.9e-51 174.5 0.1 3.3e-51 174.3 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR24468.1 - 8.4e-19 67.9 0.1 4.7e-16 59.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR24468.1 - 5.2e-16 58.8 0.0 3.4e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAR24468.1 - 0.00026 20.2 0.7 1.4 7.9 0.1 3.6 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CAR24468.1 - 0.0012 19.0 0.0 0.1 12.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAR24468.1 - 0.0033 16.6 0.9 0.87 8.6 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 CAR24468.1 - 0.005 17.3 0.0 0.71 10.3 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 CAR24468.1 - 0.0072 15.6 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CAR24468.1 - 0.01 15.0 0.0 9.8 5.2 0.0 3.6 2 1 2 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 CAR24468.1 - 0.094 12.1 0.1 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase DAO PF01266.24 CAR24468.1 - 0.13 11.8 1.4 2.1 7.8 1.4 2.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase PX PF00787.24 CAR24469.1 - 1.1e-15 57.6 0.0 1.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.21 CAR24470.1 - 1.9e-48 165.2 0.0 2.4e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family YdjC PF04794.12 CAR24470.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 YdjC-like protein PQ-loop PF04193.14 CAR24471.1 - 6.1e-35 118.8 7.6 4e-18 64.9 0.8 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 CAR24471.1 - 0.019 15.0 5.1 0.41 10.7 0.1 3.4 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange QueT PF06177.11 CAR24471.1 - 0.75 10.2 4.9 0.4 11.0 0.8 2.2 1 1 0 2 2 2 0 QueT transporter SBE2 PF17076.5 CAR24472.1 - 2.2e-246 820.1 31.5 5.6e-246 818.8 31.5 1.5 1 1 0 1 1 1 1 SBE2, cell-wall formation Abhydrolase_7 PF12715.7 CAR24472.1 - 0.017 14.4 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Abhydrolase family Exo_endo_phos_2 PF14529.6 CAR24472.1 - 0.025 14.4 0.4 0.14 12.0 0.4 2.3 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Pkinase PF00069.25 CAR24473.1 - 3.6e-69 233.1 0.0 5.3e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24473.1 - 6.6e-52 176.3 0.0 9.6e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR24473.1 - 1.9e-05 23.6 1.9 2.1e-05 23.5 0.1 1.9 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CAR24473.1 - 0.00011 21.7 0.1 0.00053 19.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAR24473.1 - 0.0095 15.9 0.9 2.3 8.1 0.4 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Syntaxin_2 PF14523.6 CAR24476.1 - 7.9e-19 67.9 15.5 1.2e-17 64.2 9.7 2.4 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 CAR24476.1 - 2.9e-14 52.8 2.6 4e-14 52.4 0.5 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CAR24476.1 - 0.00086 19.0 19.3 0.0016 18.1 19.3 1.5 1 0 0 1 1 1 1 Syntaxin Synaptobrevin PF00957.21 CAR24476.1 - 0.025 14.3 0.6 0.025 14.3 0.6 3.3 3 0 0 3 3 3 0 Synaptobrevin Sulfotransfer_2 PF03567.14 CAR24476.1 - 0.098 12.5 3.6 0.16 11.8 3.6 1.3 1 0 0 1 1 1 0 Sulfotransferase family DUF16 PF01519.16 CAR24476.1 - 0.65 10.5 18.7 0.3 11.6 2.1 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 BAR_3 PF16746.5 CAR24476.1 - 1.1 8.9 18.0 2.8 7.6 17.1 1.9 1 1 1 2 2 2 0 BAR domain of APPL family DUF1664 PF07889.12 CAR24476.1 - 7.3 6.7 15.9 5 7.2 0.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.32 CAR24477.1 - 7.6e-36 121.5 25.6 3.9e-07 30.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR24477.1 - 1.3e-15 57.4 6.6 0.00091 19.5 0.0 4.6 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Sacchrp_dh_C PF16653.5 CAR24477.1 - 0.096 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain PsbQ PF05757.11 CAR24477.1 - 0.15 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Iwr1 PF08574.10 CAR24477.1 - 5.8 8.0 7.1 2.2 9.4 2.6 2.7 3 1 0 3 3 3 0 Transcription factor Iwr1 FAD_binding_6 PF00970.24 CAR24478.1 - 3.5e-05 24.1 0.0 0.00053 20.3 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CAR24478.1 - 0.046 14.4 0.0 0.12 13.0 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain tRNA-synt_1b PF00579.25 CAR24479.1 - 7.3e-76 255.3 0.0 9.5e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Hira PF07569.11 CAR24480.1 - 4e-84 281.8 0.1 1e-83 280.4 0.1 1.8 1 0 0 1 1 1 1 TUP1-like enhancer of split ANAPC4_WD40 PF12894.7 CAR24480.1 - 0.015 15.6 0.0 0.29 11.4 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR24480.1 - 0.028 15.3 2.4 1e+02 4.0 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat CK_II_beta PF01214.18 CAR24481.1 - 3.8e-73 245.2 0.1 4.5e-73 244.9 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RecG_N PF17190.4 CAR24481.1 - 0.037 14.8 0.6 0.07 13.9 0.6 1.4 1 0 0 1 1 1 0 RecG N-terminal helical domain E1-E2_ATPase PF00122.20 CAR24482.1 - 2.5e-49 167.3 1.1 6.4e-49 165.9 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase HMA PF00403.26 CAR24482.1 - 1.2e-42 144.1 8.3 2.3e-13 50.4 0.0 3.8 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.26 CAR24482.1 - 2.4e-35 122.7 0.0 4.2e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAR24482.1 - 9.7e-08 32.1 0.1 0.0016 18.2 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR24482.1 - 0.00067 20.1 0.0 0.0019 18.6 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.14 CAR24482.1 - 0.059 13.7 2.2 8.5 6.8 0.0 3.3 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF1656 PF07869.12 CAR24482.1 - 0.12 12.4 1.5 0.61 10.1 1.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Fer2_BFD PF04324.15 CAR24482.1 - 0.43 11.0 2.8 9.7 6.6 0.0 3.6 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain HAGH_C PF16123.5 CAR24483.1 - 3.9e-19 68.9 0.2 6.2e-19 68.3 0.2 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CAR24483.1 - 3.3e-12 46.8 0.6 6.3e-11 42.7 0.6 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CAR24483.1 - 0.00041 19.9 0.5 0.0011 18.5 0.5 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CUE PF02845.16 CAR24484.1 - 1e-08 34.7 0.0 1.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain RAI1 PF08652.11 CAR24485.1 - 0.018 15.2 0.2 0.11 12.6 0.2 2.4 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Tom6 PF17112.5 CAR24488.1 - 5.2e-28 96.3 2.9 6.2e-28 96.0 2.9 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal TOM6p PF15184.6 CAR24488.1 - 0.0019 18.0 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit TOM6 homolog DEAD PF00270.29 CAR24489.1 - 1.6e-34 119.2 0.3 4.8e-34 117.6 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR24489.1 - 4.1e-29 101.1 0.1 8.9e-29 100.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CAR24489.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain CTNNB1_binding PF08347.11 CAR24489.1 - 0.035 14.3 0.8 0.055 13.7 0.8 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding CMS1 PF14617.6 CAR24489.1 - 0.082 12.2 3.0 0.18 11.1 0.0 2.6 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CAR24489.1 - 0.18 12.1 1.0 2.3 8.5 0.3 2.7 2 1 0 2 2 2 0 AAA domain STD1 PF17235.2 CAR24490.1 - 1.8e-67 227.0 0.1 2.5e-67 226.5 0.1 1.2 1 0 0 1 1 1 1 STD1/MTH1 XRN_M PF17846.1 CAR24491.1 - 8.5e-140 466.6 0.6 6.5e-103 345.0 0.0 2.5 1 1 1 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 CAR24491.1 - 6.6e-98 327.0 0.0 2.2e-97 325.3 0.0 1.9 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus CCDC84 PF14968.6 CAR24491.1 - 0.61 9.6 4.9 1.4 8.5 4.9 1.6 1 0 0 1 1 1 0 Coiled coil protein 84 RTA1 PF04479.13 CAR24492.1 - 1.4e-72 243.7 12.4 1.4e-72 243.7 12.4 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF3493 PF11998.8 CAR24492.1 - 3.3 7.9 7.0 6.8 6.9 3.2 2.4 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 Acyltransferase PF01553.21 CAR24493.1 - 1.4e-06 27.9 0.0 1.2e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase GPDPase_memb PF10110.9 CAR24493.1 - 0.029 13.2 3.8 0.046 12.5 3.8 1.2 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase BPD_transp_1 PF00528.22 CAR24493.1 - 0.17 11.6 1.4 0.42 10.3 0.5 2.0 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component TRAPP PF04051.16 CAR24494.1 - 3.3e-33 114.5 0.0 4e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Nro1 PF12753.7 CAR24495.1 - 4.4e-173 576.0 12.4 4.9e-173 575.8 12.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 FAST_1 PF06743.15 CAR24495.1 - 0.00024 21.0 0.0 0.0092 15.9 0.0 2.7 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 TPR_14 PF13428.6 CAR24495.1 - 0.16 12.9 4.3 68 4.7 0.0 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TP_methylase PF00590.20 CAR24496.1 - 2.5e-41 142.0 0.1 4.1e-41 141.3 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 CAR24496.1 - 1.7e-09 36.9 0.1 3.5e-09 35.9 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 CAR24496.1 - 1.8e-05 25.1 0.0 4.5e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CAR24496.1 - 0.0011 18.6 0.8 0.27 10.9 0.2 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Hydrolase_like PF13242.6 CAR24497.1 - 1.3e-27 95.6 0.0 7.3e-27 93.2 0.0 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CAR24497.1 - 1.5e-22 79.6 0.0 2.8e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR24497.1 - 0.0043 17.2 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase zf-AN1 PF01428.16 CAR24498.1 - 3.8e-11 42.9 6.3 3.8e-11 42.9 6.3 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger CIAPIN1 PF05093.13 CAR24499.1 - 1.2e-40 138.1 4.4 1.2e-40 138.1 4.4 2.0 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CAR24499.1 - 1.9e-30 105.8 0.0 2.8e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus zf-CSL PF05207.13 CAR24499.1 - 0.66 9.8 4.6 2.2 8.0 4.0 2.3 1 1 1 2 2 2 0 CSL zinc finger Flavoprotein PF02441.19 CAR24500.1 - 1.9e-50 170.7 0.2 2.7e-50 170.2 0.2 1.2 1 0 0 1 1 1 1 Flavoprotein PPP4R2 PF09184.11 CAR24500.1 - 0.0011 18.6 15.0 0.0011 18.6 15.0 2.4 2 0 0 2 2 2 1 PPP4R2 Nop14 PF04147.12 CAR24500.1 - 0.016 13.5 29.2 0.025 12.8 29.2 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 CAR24500.1 - 0.083 11.4 18.8 0.12 10.9 18.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CNDH2_C PF16858.5 CAR24500.1 - 3.6 7.4 12.5 9.2 6.0 12.5 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NOA36 PF06524.12 CAR24500.1 - 7 5.9 41.2 16 4.7 41.2 1.5 1 0 0 1 1 1 0 NOA36 protein PIN_6 PF17146.4 CAR24501.1 - 5.2e-32 110.2 0.0 1.2e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CAR24501.1 - 6.2e-26 90.3 0.3 1.4e-25 89.3 0.3 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_9 PF14369.6 CAR24501.1 - 0.041 14.1 0.5 0.1 12.9 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon DUF3475 PF11961.8 CAR24501.1 - 0.056 13.5 0.4 4.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) Tau95_N PF17682.1 CAR24501.1 - 0.07 13.3 0.5 0.17 12.1 0.5 1.6 1 0 0 1 1 1 0 Tau95 Triple barrel domain zinc_ribbon_12 PF11331.8 CAR24501.1 - 0.49 10.2 1.9 1.4 8.8 1.9 1.8 1 0 0 1 1 1 0 Probable zinc-ribbon domain Peptidase_U57 PF05582.12 CAR24501.1 - 0.52 9.5 3.5 1.3 8.3 3.5 1.6 1 0 0 1 1 1 0 YabG peptidase U57 Presenilin PF01080.17 CAR24501.1 - 1.3 7.7 11.8 2.8 6.6 11.8 1.5 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.11 CAR24501.1 - 5.5 6.3 9.3 9.8 5.5 9.3 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SGS PF05002.15 CAR24502.1 - 2.2e-27 95.0 2.4 4e-27 94.2 1.0 2.2 2 0 0 2 2 2 1 SGS domain CS PF04969.16 CAR24502.1 - 2.1e-10 41.4 0.1 4.5e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 CS domain TPR_14 PF13428.6 CAR24502.1 - 0.00011 22.7 2.6 0.0034 18.1 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR24502.1 - 0.00015 21.6 7.6 0.35 11.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR24502.1 - 0.0073 16.1 8.8 0.17 11.8 0.2 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24502.1 - 0.028 14.7 8.1 1.4 9.3 3.6 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAR24502.1 - 0.15 12.6 8.2 5.6 7.6 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR24502.1 - 0.24 11.6 6.6 0.94 9.7 0.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CAR24502.1 - 1.6 9.5 8.1 1.5 9.7 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR24502.1 - 4 8.2 5.4 1.4 9.7 0.1 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.12 CAR24503.1 - 3.8e-103 346.2 30.7 6.1e-103 345.6 30.7 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) ACT_5 PF13710.6 CAR24503.1 - 0.12 12.3 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 ACT domain NRN1 PF15056.6 CAR24503.1 - 0.12 12.4 0.5 0.46 10.6 0.5 2.0 1 0 0 1 1 1 0 Neuritin protein family Lipoprotein_2 PF00921.17 CAR24503.1 - 1 8.9 7.1 6.5 6.2 0.9 2.4 2 0 0 2 2 2 0 Borrelia lipoprotein DUF4047 PF13256.6 CAR24503.1 - 2.3 8.5 6.4 9.5 6.4 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) DUF1664 PF07889.12 CAR24503.1 - 6.4 6.8 6.3 3.9 7.5 1.6 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4239 PF14023.6 CAR24503.1 - 9.7 5.8 8.5 14 5.4 0.1 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF4239) DUF2340 PF10209.9 CAR24504.1 - 9.3e-51 171.3 0.8 1.1e-50 171.1 0.8 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF676 PF05057.14 CAR24505.1 - 2.2e-50 171.2 0.0 3.1e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CAR24505.1 - 5.5e-06 26.3 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CAR24505.1 - 0.0029 17.5 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Prominin PF05478.11 CAR24505.1 - 0.041 11.8 0.0 0.057 11.4 0.0 1.1 1 0 0 1 1 1 0 Prominin Sld7_N PF18636.1 CAR24506.1 - 3.2e-29 101.8 0.0 5.5e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Sld7_C PF18596.1 CAR24506.1 - 2.1e-23 82.2 0.0 3.7e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Sld7 C-terminal domain Pkinase PF00069.25 CAR24507.1 - 7.2e-56 189.5 0.0 8.7e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24507.1 - 1.3e-15 57.5 0.0 1.6e-15 57.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR24507.1 - 1.8e-06 28.0 0.2 4.7e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR24507.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CAR24507.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3081 PF11280.8 CAR24508.1 - 0.077 12.8 0.6 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Ribosomal_L3 PF00297.22 CAR24510.1 - 5.7e-188 624.4 9.8 6.4e-188 624.3 9.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 zf-HC5HC2H_2 PF13832.6 CAR24511.1 - 0.013 15.6 1.7 0.027 14.6 1.7 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF3987 PF13148.6 CAR24511.1 - 0.024 13.7 2.1 0.039 13.0 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) zf-HC5HC2H PF13771.6 CAR24511.1 - 0.028 14.7 5.2 0.063 13.5 5.2 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain F-box PF00646.33 CAR24511.1 - 0.17 11.8 0.3 3.6 7.6 0.0 2.4 2 0 0 2 2 2 0 F-box domain Cytochrom_C1 PF02167.15 CAR24512.1 - 6.5e-95 317.0 0.0 8e-95 316.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CAR24512.1 - 0.00089 19.5 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CAR24512.1 - 0.0019 19.3 0.1 0.0053 17.9 0.1 2.0 1 1 0 1 1 1 1 Cytochrome c GST_N_2 PF13409.6 CAR24513.1 - 1.6e-21 76.4 0.0 5.5e-21 74.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CAR24513.1 - 1.9e-09 37.4 0.0 3.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CAR24513.1 - 0.024 14.8 0.0 0.077 13.2 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Alg6_Alg8 PF03155.15 CAR24515.1 - 9.4e-166 552.5 40.3 1.1e-165 552.3 40.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ank_5 PF13857.6 CAR24515.1 - 0.2 12.0 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Vps5 PF09325.10 CAR24516.1 - 6.9e-78 261.4 12.3 1.6e-77 260.2 12.3 1.6 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CAR24516.1 - 1.9e-23 82.6 1.1 4e-23 81.6 0.2 2.0 2 0 0 2 2 2 1 PX domain BAR_3_WASP_bdg PF10456.9 CAR24516.1 - 0.074 12.5 1.5 0.11 12.0 0.4 1.7 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Lactamase_B_4 PF13691.6 CAR24517.1 - 3.7e-27 93.8 0.1 1e-26 92.4 0.1 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CAR24517.1 - 1.3e-12 47.7 0.0 5.5e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DUF1947 PF09183.10 CAR24517.1 - 0.033 14.5 0.0 0.095 13.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Lactamase_B PF00753.27 CAR24517.1 - 0.059 13.4 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily RabGAP-TBC PF00566.18 CAR24518.1 - 4.2e-49 167.1 0.7 4.2e-49 167.1 0.7 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain KcnmB2_inactiv PF09303.10 CAR24518.1 - 0.14 12.0 0.6 0.58 10.0 0.1 2.2 2 0 0 2 2 2 0 KCNMB2, ball and chain domain THF_DHG_CYH PF00763.23 CAR24519.1 - 5.6e-26 91.1 0.0 1.5e-25 89.7 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CAR24519.1 - 3.6e-17 62.2 0.0 3.7e-10 39.4 0.0 2.5 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FTP PF07504.13 CAR24519.1 - 0.0028 17.4 1.0 0.0062 16.3 1.0 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peripla_BP_4 PF13407.6 CAR24519.1 - 0.077 12.6 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 Periplasmic binding protein domain Brix PF04427.18 CAR24520.1 - 1.1e-39 136.5 0.5 1.6e-39 136.0 0.5 1.2 1 0 0 1 1 1 1 Brix domain DUF1086 PF06461.11 CAR24520.1 - 0.019 14.8 0.2 0.019 14.8 0.2 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1086) DUF4611 PF15387.6 CAR24520.1 - 0.056 13.7 1.2 0.12 12.6 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Kri1 PF05178.12 CAR24520.1 - 0.2 12.2 4.7 0.1 13.2 2.2 1.9 2 0 0 2 2 2 0 KRI1-like family Nucleoporin_N PF08801.11 CAR24521.1 - 3.6e-60 203.9 4.1 5.9e-60 203.2 4.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CAR24521.1 - 1.3e-27 96.9 16.5 1.1e-26 93.7 16.5 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal WASH-7_C PF14746.6 CAR24521.1 - 0.021 14.5 0.2 0.31 10.7 0.2 2.6 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal CsgA PF17334.2 CAR24521.1 - 0.063 14.0 6.3 1.4 9.7 0.3 3.9 4 0 0 4 4 4 0 Minor curli fiber component A DASH_Dad2 PF08654.10 CAR24522.1 - 9.2e-31 106.2 2.2 1.2e-30 105.8 2.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 CAR24522.1 - 1.6e-05 24.5 1.6 3.1e-05 23.7 1.6 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 NuiA PF07924.11 CAR24522.1 - 0.08 13.3 1.0 2.6 8.4 0.0 2.2 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein SPC22 PF04573.12 CAR24522.1 - 0.1 12.1 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Signal peptidase subunit Mis14 PF08641.12 CAR24522.1 - 0.11 12.8 0.4 0.11 12.8 0.4 1.7 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Shugoshin_N PF07558.11 CAR24523.1 - 8.9e-17 60.7 3.1 2.4e-16 59.3 3.1 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 CAR24523.1 - 5e-09 35.8 7.3 1.2e-08 34.5 7.3 1.7 1 0 0 1 1 1 1 Shugoshin C terminus CHZ PF09649.10 CAR24523.1 - 0.011 15.1 1.6 0.086 12.3 0.8 2.6 2 0 0 2 2 2 0 Histone chaperone domain CHZ GIT_CC PF16559.5 CAR24523.1 - 0.016 15.0 1.0 0.06 13.2 1.0 2.0 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor Thymidylat_synt PF00303.19 CAR24524.1 - 1e-114 382.2 0.0 1.2e-114 382.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Beta_protein PF14350.6 CAR24524.1 - 0.16 11.4 0.0 0.43 9.9 0.0 1.6 2 0 0 2 2 2 0 Beta protein Syntaxin-18_N PF10496.9 CAR24525.1 - 2.6e-16 59.7 1.9 2.6e-16 59.7 1.9 2.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CAR24525.1 - 2.4e-06 27.4 0.1 2.4e-06 27.4 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Sec20 PF03908.13 CAR24525.1 - 0.014 15.2 1.2 0.014 15.2 1.2 2.8 2 1 1 3 3 3 0 Sec20 Nop PF01798.18 CAR24525.1 - 0.11 12.0 5.5 0.045 13.2 3.1 1.6 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin IR1-M PF12185.8 CAR24525.1 - 0.11 12.5 0.9 0.88 9.6 0.1 2.6 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain COG5 PF10392.9 CAR24525.1 - 0.14 12.4 17.3 0.22 11.7 1.1 2.9 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Spore_III_AB PF09548.10 CAR24525.1 - 4.7 7.3 11.9 20 5.2 7.2 3.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GTP_EFTU PF00009.27 CAR24526.1 - 1.4e-43 148.7 0.0 2.9e-43 147.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CAR24526.1 - 3.2e-10 40.2 6.2 3.2e-10 40.2 6.2 2.1 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 CAR24526.1 - 4.3e-09 36.7 0.5 1e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CAR24526.1 - 1.4e-08 34.8 0.1 0.00021 21.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CAR24526.1 - 0.00032 21.0 0.0 0.00074 19.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Arf PF00025.21 CAR24526.1 - 0.0017 17.8 0.1 0.34 10.3 0.0 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family Roc PF08477.13 CAR24526.1 - 0.005 17.1 1.3 0.54 10.5 0.0 2.8 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AUX_IAA PF02309.16 CAR24526.1 - 0.013 15.4 1.2 0.025 14.4 1.2 1.4 1 0 0 1 1 1 0 AUX/IAA family FeoB_N PF02421.18 CAR24526.1 - 0.018 14.6 0.1 0.3 10.6 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B MRP-L20 PF12824.7 CAR24528.1 - 4.2e-48 163.6 5.1 6.7e-48 163.0 5.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Pneumo_att_G PF05539.11 CAR24528.1 - 0.054 13.1 0.8 0.067 12.8 0.8 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G HA2 PF04408.23 CAR24529.1 - 5.9e-24 84.4 0.0 3e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR24529.1 - 1.3e-15 57.5 0.0 3.7e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR24529.1 - 3.6e-14 53.0 0.0 1.3e-13 51.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR24529.1 - 4.7e-07 29.7 0.3 1.4e-06 28.2 0.3 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR24529.1 - 5.1e-06 26.8 0.1 2.3e-05 24.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CAR24529.1 - 0.0068 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.9 CAR24529.1 - 0.0073 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 CAR24529.1 - 0.0078 16.5 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR24529.1 - 0.0081 15.9 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CAR24529.1 - 0.0091 16.0 0.8 0.26 11.3 0.5 2.8 2 1 0 2 2 1 1 AAA domain PhoH PF02562.16 CAR24529.1 - 0.018 14.5 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CAR24529.1 - 0.019 14.9 0.0 8.8 6.3 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CAR24529.1 - 0.023 14.7 0.6 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_16 PF13191.6 CAR24529.1 - 0.041 14.3 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CAR24529.1 - 0.061 13.8 1.2 0.41 11.1 0.0 2.7 2 1 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 CAR24529.1 - 0.093 12.2 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CAR24529.1 - 0.096 12.8 0.1 0.47 10.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CAR24529.1 - 0.11 12.2 0.1 2.2 8.0 0.0 2.3 1 1 1 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CAR24529.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 CAR24529.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain Peptidase_M48 PF01435.18 CAR24530.1 - 2e-31 109.3 0.0 4.9e-31 108.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 Kin17_mid PF10357.9 CAR24531.1 - 2.8e-42 143.6 4.1 4.8e-42 142.8 4.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 CAR24531.1 - 3.8e-05 23.9 3.9 8.4e-05 22.7 3.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR24531.1 - 5.2e-05 23.5 3.2 0.00012 22.3 3.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAR24531.1 - 0.2 12.0 7.4 0.065 13.6 3.1 2.3 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) SNARE_assoc PF09335.11 CAR24532.1 - 8.7e-16 58.5 5.8 8.7e-16 58.5 5.8 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein TctB PF07331.11 CAR24532.1 - 0.00074 19.8 5.1 0.00074 19.8 5.1 2.2 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family WSS_VP PF12175.8 CAR24532.1 - 0.065 12.7 0.3 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP RTP1_C1 PF10363.9 CAR24532.1 - 0.13 12.5 0.6 0.69 10.1 0.1 2.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4381 PF14316.6 CAR24532.1 - 0.3 11.3 3.9 28 4.9 0.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF2304 PF10066.9 CAR24532.1 - 0.73 10.1 9.2 1.6 9.0 5.3 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Abhydrolase_9_N PF15420.6 CAR24532.1 - 1.9 8.4 7.6 2.8 7.9 4.3 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus adh_short_C2 PF13561.6 CAR24533.1 - 3.6e-59 200.2 1.0 4.4e-59 199.9 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR24533.1 - 1.8e-39 135.3 1.9 2.1e-39 135.0 1.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR24533.1 - 5.6e-10 39.4 0.7 1.2e-09 38.3 0.7 1.6 1 1 1 2 2 2 1 KR domain IMPDH PF00478.25 CAR24533.1 - 0.035 13.1 0.2 0.33 9.9 0.1 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain URO-D PF01208.17 CAR24533.1 - 0.052 12.7 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Glyco_tranf_2_3 PF13641.6 CAR24533.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 U3_snoRNA_assoc PF08297.11 CAR24535.1 - 4.9e-19 68.8 6.4 4.9e-19 68.8 6.4 3.2 2 1 0 2 2 2 1 U3 snoRNA associated DUF4661 PF15576.6 CAR24535.1 - 3.7 7.4 14.4 2.6 7.9 13.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4661) SOBP PF15279.6 CAR24535.1 - 9.5 6.7 15.3 14 6.2 15.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.22 CAR24536.1 - 1.8e-34 119.4 16.3 1.7e-20 73.5 4.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF63 PF01889.17 CAR24536.1 - 0.066 13.4 2.8 0.076 13.2 0.3 2.0 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 LHC PF00556.20 CAR24536.1 - 2.6 8.3 0.0 2.6 8.3 0.0 3.9 4 0 0 4 4 4 0 Antenna complex alpha/beta subunit ABC2_membrane_5 PF13346.6 CAR24536.1 - 2.9 7.4 12.5 0.32 10.5 5.4 2.6 3 0 0 3 3 3 0 ABC-2 family transporter protein TPR_2 PF07719.17 CAR24537.1 - 9.1e-08 31.7 5.1 0.052 13.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAR24537.1 - 4.9e-07 29.3 3.9 0.34 10.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24537.1 - 4.3e-05 23.7 0.3 0.021 15.1 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat F-box-like PF12937.7 CAR24537.1 - 8.5e-05 22.4 2.3 0.00021 21.1 2.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR24537.1 - 0.00016 21.5 2.9 0.00048 19.9 2.9 1.8 1 0 0 1 1 1 1 F-box domain TPR_8 PF13181.6 CAR24537.1 - 0.00031 20.7 2.6 0.62 10.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAR24537.1 - 0.00068 19.5 0.6 1.6 8.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat LRR_4 PF12799.7 CAR24537.1 - 0.0039 17.5 7.6 0.2 12.1 0.1 5.3 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAR24537.1 - 0.05 13.7 0.1 16 5.9 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat TPR_17 PF13431.6 CAR24537.1 - 0.07 13.5 0.3 14 6.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box_4 PF15966.5 CAR24537.1 - 0.26 11.2 1.2 0.6 10.0 0.3 2.1 2 0 0 2 2 2 0 F-box LRR_1 PF00560.33 CAR24537.1 - 9.5 7.2 14.2 39 5.3 0.2 5.9 6 1 0 6 6 4 0 Leucine Rich Repeat DUF3336 PF11815.8 CAR24538.1 - 6.7e-35 119.8 8.8 1.5e-34 118.6 8.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CAR24538.1 - 1e-25 91.1 0.0 2.4e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Rpn3_C PF08375.11 CAR24539.1 - 4.6e-21 75.0 4.0 6.8e-21 74.5 1.4 2.3 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CAR24539.1 - 4.9e-19 68.8 2.2 2.1e-18 66.8 0.3 2.5 2 0 0 2 2 2 1 PCI domain Med17 PF10156.9 CAR24540.1 - 1.6e-153 511.8 7.5 2e-153 511.4 7.5 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ilm1 PF10311.9 CAR24541.1 - 2.1e-09 37.2 8.0 0.00033 20.4 3.3 2.1 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 JmjC PF02373.22 CAR24542.1 - 6.2e-39 133.0 0.3 1.2e-38 132.0 0.3 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 CAR24542.1 - 3.4e-12 46.1 5.2 3.4e-12 46.1 5.2 2.3 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 CAR24542.1 - 3.1e-08 33.4 0.0 7.4e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 jmjN domain RWP-RK PF02042.15 CAR24542.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain zf-HC5HC2H PF13771.6 CAR24542.1 - 0.013 15.7 0.2 0.041 14.1 0.2 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 CAR24542.1 - 0.022 14.9 3.5 0.065 13.4 3.5 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain PHD_2 PF13831.6 CAR24542.1 - 0.52 9.9 3.3 0.38 10.4 0.7 2.2 2 0 0 2 2 2 0 PHD-finger Fer4_16 PF13484.6 CAR24542.1 - 1.2 10.1 6.7 1.3 10.0 0.1 2.9 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Sporozoite_P67 PF05642.11 CAR24542.1 - 8.4 4.3 5.0 4.6 5.2 0.3 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen E7 PF00527.18 CAR24542.1 - 8.7 6.6 8.5 0.52 10.5 2.2 2.2 3 0 0 3 3 3 0 E7 protein, Early protein P5CR_dimer PF14748.6 CAR24543.1 - 5.2e-31 107.0 0.3 9.3e-31 106.2 0.3 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CAR24543.1 - 5.8e-10 39.6 0.0 1.2e-09 38.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IF2_N PF04760.15 CAR24543.1 - 0.041 13.7 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region ATP-synt_ab PF00006.25 CAR24544.1 - 4.7e-62 209.4 0.0 8.4e-62 208.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CAR24544.1 - 2.7e-22 79.1 3.2 2.7e-22 79.1 3.2 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 CAR24544.1 - 0.0022 17.2 1.0 0.078 12.2 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain ATPase PF06745.13 CAR24544.1 - 0.0042 16.5 0.2 0.0075 15.6 0.2 1.4 1 0 0 1 1 1 1 KaiC NACHT PF05729.12 CAR24544.1 - 0.036 14.0 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 CAR24544.1 - 0.041 13.8 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 CAR24544.1 - 0.063 13.7 0.1 0.77 10.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T3SS_ATPase_C PF18269.1 CAR24544.1 - 0.067 13.1 0.9 0.43 10.5 0.9 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain AAA_16 PF13191.6 CAR24544.1 - 0.092 13.1 0.8 0.29 11.5 0.2 2.2 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CAR24544.1 - 0.13 12.7 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CAR24544.1 - 0.46 10.8 3.7 0.48 10.8 0.1 2.5 3 0 0 3 3 3 0 AAA domain GCV_T PF01571.21 CAR24545.1 - 0.044 13.1 0.0 5.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain Ribosomal_S7 PF00177.21 CAR24546.1 - 2.3e-37 127.9 2.0 3.6e-37 127.3 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.16 CAR24547.1 - 1.7e-31 109.4 49.4 3.2e-24 85.5 20.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CAR24547.1 - 7.8e-09 34.6 23.4 0.00012 20.8 11.7 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 CAR24547.1 - 7.6e-06 25.0 6.1 7.6e-06 25.0 6.1 3.0 1 1 2 3 3 3 2 MFS_1 like family OATP PF03137.20 CAR24547.1 - 0.00016 20.1 0.5 0.00016 20.1 0.5 3.5 2 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CAR24547.1 - 0.00022 20.2 19.6 0.00047 19.1 19.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.18 CAR24548.1 - 2.2e-08 34.1 11.0 4.2e-08 33.2 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEXIM PF15313.6 CAR24548.1 - 0.012 15.8 0.2 0.49 10.6 0.2 2.7 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein KxDL PF10241.9 CAR24548.1 - 0.059 13.6 1.5 0.19 12.1 1.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein ACOX PF01756.19 CAR24548.1 - 0.08 12.5 0.3 0.19 11.3 0.3 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase eIF2_C PF09173.11 CAR24549.1 - 2.1e-34 117.6 0.4 5.4e-34 116.3 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CAR24549.1 - 2e-23 82.9 0.1 1.9e-22 79.8 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CAR24549.1 - 3.1e-12 46.7 0.4 9e-12 45.2 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CAR24549.1 - 0.002 18.1 0.1 0.047 13.6 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CAR24549.1 - 0.0031 17.6 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CAR24549.1 - 0.039 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RGS PF00615.19 CAR24550.1 - 1.7e-20 73.4 1.9 7.7e-15 55.2 0.2 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.21 CAR24550.1 - 2.7e-10 40.2 0.0 8.6e-09 35.3 0.0 2.7 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Pkinase PF00069.25 CAR24551.1 - 1e-73 248.0 0.0 1.6e-73 247.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24551.1 - 1e-29 103.6 0.0 4.3e-29 101.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR24551.1 - 3.5e-05 22.9 0.0 6.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAR24551.1 - 0.08 12.0 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 ORC4_C PF14629.6 CAR24552.1 - 7.6e-35 120.3 2.1 1.3e-34 119.5 2.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 CAR24552.1 - 0.00047 20.6 0.1 0.0012 19.2 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-RING_2 PF13639.6 CAR24553.1 - 4.4e-10 39.7 14.4 4.4e-10 39.7 14.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CAR24553.1 - 8.3e-08 31.8 7.1 2.3e-07 30.4 7.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 CAR24553.1 - 6.2e-07 29.6 17.4 6.4e-07 29.6 13.7 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CAR24553.1 - 3.3e-05 23.8 11.9 5.9e-05 23.0 3.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR24553.1 - 7.2e-05 22.5 12.0 0.00017 21.3 12.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR24553.1 - 8.9e-05 22.3 13.9 8.9e-05 22.3 13.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR24553.1 - 0.00017 21.5 13.3 0.00036 20.4 13.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CAR24553.1 - 0.00017 21.5 10.8 0.00064 19.7 8.2 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CAR24553.1 - 0.001 18.9 12.5 0.0023 17.8 12.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CAR24553.1 - 0.0027 17.5 11.4 0.0056 16.5 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4832 PF16116.5 CAR24553.1 - 0.1 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) Rad50_zn_hook PF04423.14 CAR24553.1 - 0.33 10.8 6.6 3.2 7.7 2.7 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Zn_ribbon_17 PF17120.5 CAR24553.1 - 0.78 9.4 13.7 0.34 10.6 10.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CAR24553.1 - 4 7.3 10.6 18 5.2 10.7 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 CAR24554.1 - 1.5e-05 24.7 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fmp27_WPPW PF10359.9 CAR24555.1 - 4.1e-114 382.1 16.2 4.1e-114 382.1 16.2 2.6 2 1 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 CAR24555.1 - 2.2e-90 304.1 24.4 2.2e-90 304.1 24.4 3.1 3 1 0 3 3 3 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 CAR24555.1 - 3.1e-78 263.8 6.8 3.1e-78 263.8 6.8 3.9 3 1 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CAR24555.1 - 3.4e-55 186.4 0.0 1.1e-54 184.8 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CAR24555.1 - 1.6e-52 177.6 0.1 1e-51 174.9 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CAR24555.1 - 2.2e-29 102.2 1.7 8.5e-29 100.3 0.0 3.1 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain MMS1_N PF10433.9 CAR24556.1 - 0.006 15.3 0.0 14 4.1 0.0 4.2 3 2 1 5 5 5 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ras PF00071.22 CAR24557.1 - 1.3e-55 187.4 0.0 1.6e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24557.1 - 3.2e-21 75.8 0.0 5.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24557.1 - 1.1e-07 31.4 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR24557.1 - 0.0008 19.0 0.1 0.0014 18.2 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAR24557.1 - 0.048 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 CAR24558.1 - 3.1e-55 186.2 0.0 3.8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24558.1 - 1.5e-21 76.8 0.0 2.8e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24558.1 - 3e-07 30.1 0.0 4.5e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR24558.1 - 0.00013 21.6 0.0 0.00034 20.2 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAR24558.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.21 CAR24559.1 - 7.5e-21 73.6 0.3 1.2e-20 73.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.19 CAR24560.1 - 4.6e-43 147.3 0.0 6.1e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF4727 PF15856.5 CAR24560.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) Med10 PF09748.9 CAR24561.1 - 1.7e-36 124.9 1.4 1.9e-36 124.6 1.4 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2203 PF09969.9 CAR24561.1 - 0.023 15.4 0.6 2.7 8.7 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Prominin PF05478.11 CAR24561.1 - 0.037 12.0 0.3 0.043 11.8 0.3 1.0 1 0 0 1 1 1 0 Prominin BLOC1_2 PF10046.9 CAR24561.1 - 0.042 14.2 0.9 0.43 10.9 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RPW8 PF05659.11 CAR24561.1 - 0.042 13.5 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FlgO PF17680.1 CAR24561.1 - 0.054 13.2 1.0 3.6 7.3 0.2 2.1 1 1 0 2 2 2 0 FlgO protein ANAPC4_WD40 PF12894.7 CAR24562.1 - 0.00011 22.4 1.3 0.21 11.9 0.2 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR24562.1 - 0.1 13.5 2.8 23 6.1 0.1 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat PQQ_3 PF13570.6 CAR24562.1 - 0.17 12.4 0.0 7.1 7.3 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain Nramp PF01566.18 CAR24563.1 - 4.4e-85 285.8 25.6 8.2e-51 173.1 8.1 2.3 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein RRM_1 PF00076.22 CAR24564.1 - 8e-34 115.3 0.2 8.5e-17 60.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR24564.1 - 2.3e-11 43.7 0.2 6.5e-06 26.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif Glyco_H_20C_C PF18088.1 CAR24564.1 - 0.0056 16.5 4.2 0.011 15.6 4.2 1.4 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain TFIIA PF03153.13 CAR24564.1 - 0.054 13.5 34.9 0.16 12.0 10.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_3 PF08777.11 CAR24564.1 - 0.083 12.9 0.1 0.92 9.6 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif DUF2232 PF09991.9 CAR24564.1 - 1.6 7.8 7.5 2.9 7.0 7.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Collagen PF01391.18 CAR24564.1 - 2.6 7.9 14.1 14 5.6 0.3 2.8 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) UPF0020 PF01170.18 CAR24565.1 - 2e-11 43.9 0.0 6.8e-10 38.9 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 MethyltransfD12 PF02086.15 CAR24565.1 - 0.009 15.7 0.1 0.76 9.4 0.0 2.5 1 1 1 2 2 2 2 D12 class N6 adenine-specific DNA methyltransferase N6_Mtase PF02384.16 CAR24565.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.5 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 CAR24565.1 - 0.094 12.4 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 DNA methylase Ras PF00071.22 CAR24566.1 - 8.5e-32 110.0 0.0 2.3e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CAR24566.1 - 1.2e-19 70.7 0.0 7.8e-14 51.9 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24566.1 - 0.00046 19.7 0.3 0.0034 16.9 0.1 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_7 PF12775.7 CAR24566.1 - 0.0062 16.1 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ORC2 PF04084.14 CAR24566.1 - 0.041 12.8 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 2 TRM13 PF05206.14 CAR24567.1 - 3.3e-75 253.0 0.0 7.7e-75 251.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 CAR24567.1 - 5.1e-13 48.5 1.2 1.1e-12 47.4 1.2 1.6 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 CAR24567.1 - 3e-09 36.6 0.7 7e-09 35.4 0.7 1.7 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_23 PF13489.6 CAR24567.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ldh_1_N PF00056.23 CAR24568.1 - 6.5e-36 123.5 0.1 1.4e-35 122.5 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAR24568.1 - 2.1e-31 109.1 0.0 3.7e-29 101.8 0.0 2.3 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Bax1-I PF01027.20 CAR24569.1 - 9e-42 143.2 18.6 1.3e-41 142.7 18.6 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ribosomal_L23eN PF03939.13 CAR24570.1 - 1.8e-18 66.5 9.3 1.8e-18 66.5 9.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CAR24570.1 - 1.9e-15 56.9 3.5 1.9e-15 56.9 3.5 2.8 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_S11 PF00411.19 CAR24571.1 - 1.7e-05 25.2 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Dicer_dimer PF03368.14 CAR24571.1 - 0.0069 16.5 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Dicer dimerisation domain Pkinase PF00069.25 CAR24572.1 - 5.9e-59 199.6 0.0 7.1e-59 199.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24572.1 - 3.9e-30 105.0 0.0 5.4e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR24572.1 - 4.9e-06 26.1 0.0 7.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR24572.1 - 0.00063 19.7 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR24572.1 - 0.0026 17.2 0.1 0.0037 16.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CAR24572.1 - 0.03 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0220 PF05255.11 CAR24573.1 - 2.8e-72 241.7 3.2 3.2e-72 241.5 3.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PrgI PF12666.7 CAR24573.1 - 0.068 13.9 2.9 0.27 12.0 0.1 2.2 2 0 0 2 2 2 0 PrgI family protein Phage_holin_5_2 PF16079.5 CAR24573.1 - 0.67 10.3 5.6 0.2 12.0 0.6 2.5 1 1 2 3 3 3 0 Phage holin family Hol44, in holin superfamily V Kri1_C PF12936.7 CAR24574.1 - 1.7e-28 98.6 2.8 1.7e-28 98.6 2.8 4.2 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 CAR24574.1 - 3.3e-18 66.1 10.1 3.3e-18 66.1 10.1 5.8 3 1 3 6 6 6 1 KRI1-like family CorA PF01544.18 CAR24575.1 - 2.8e-39 135.2 0.5 1.7e-37 129.3 0.5 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-DNL PF05180.12 CAR24577.1 - 4.8e-31 106.5 2.0 7.6e-31 105.9 2.0 1.3 1 0 0 1 1 1 1 DNL zinc finger HypA PF01155.19 CAR24577.1 - 0.018 15.1 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UPF0167 PF03691.14 CAR24577.1 - 0.018 14.8 0.2 0.026 14.3 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zinc_ribbon_4 PF13717.6 CAR24577.1 - 0.024 14.6 0.7 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.13 CAR24577.1 - 0.024 14.7 1.7 0.042 13.9 1.7 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TFIIS_C PF01096.18 CAR24577.1 - 0.03 14.2 0.9 2.5 8.0 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.10 CAR24577.1 - 0.055 13.6 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-CSL PF05207.13 CAR24577.1 - 0.057 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 CSL zinc finger TF_Zn_Ribbon PF08271.12 CAR24577.1 - 0.11 12.1 0.9 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-trcl PF13451.6 CAR24577.1 - 0.18 11.7 1.5 0.44 10.5 1.5 1.6 1 1 0 1 1 1 0 Probable zinc-ribbon domain F-box-like PF12937.7 CAR24578.1 - 1.5e-07 31.2 0.8 4.5e-07 29.7 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR24578.1 - 1.9e-05 24.4 1.2 6.6e-05 22.7 0.6 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CAR24578.1 - 0.0023 17.8 0.4 0.0056 16.5 0.4 1.6 1 0 0 1 1 1 1 F-box Glyco_hydro_72 PF03198.14 CAR24579.1 - 6e-137 456.1 0.8 8e-137 455.7 0.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Med23 PF11573.8 CAR24579.1 - 0.083 10.5 0.0 0.13 9.9 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 23 tRNA_anti-codon PF01336.25 CAR24580.1 - 1.1e-09 38.2 0.1 1.9e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 CAR24580.1 - 1.2e-07 32.3 0.2 5.3e-07 30.2 0.0 2.2 3 0 0 3 3 3 1 Replication protein A C terminal HTH_IclR PF09339.10 CAR24580.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain CDC24_OB3 PF17244.2 CAR24580.1 - 0.061 13.0 0.2 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 TPR_2 PF07719.17 CAR24581.1 - 2.3e-08 33.5 1.6 0.0095 16.0 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR24581.1 - 5.2e-08 32.5 0.1 0.027 14.6 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR24581.1 - 3.1e-07 29.9 0.5 0.66 9.9 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR24581.1 - 0.00072 20.0 0.3 0.083 13.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAR24581.1 - 0.013 15.8 0.9 0.096 13.1 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24581.1 - 0.014 15.7 1.3 2.9 8.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAR24581.1 - 1.5 8.8 3.6 3.7 7.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR24581.1 - 7.2 6.9 5.8 62 3.9 0.4 4.0 4 1 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Myb_DNA-bind_5 PF13873.6 CAR24582.1 - 0.0084 16.2 0.2 0.018 15.1 0.2 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain AIP3 PF03915.13 CAR24582.1 - 0.011 14.9 1.0 0.015 14.4 1.0 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 Myb_DNA-bind_3 PF12776.7 CAR24582.1 - 0.022 15.7 2.0 0.028 15.4 0.2 2.0 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain FAM76 PF16046.5 CAR24582.1 - 0.045 13.1 2.7 0.077 12.3 2.7 1.3 1 0 0 1 1 1 0 FAM76 protein KRAB PF01352.27 CAR24582.1 - 0.091 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 KRAB box ATP11 PF06644.11 CAR24583.1 - 3.8e-90 302.4 7.2 4.8e-90 302.0 7.2 1.1 1 0 0 1 1 1 1 ATP11 protein DUF1366 PF07104.11 CAR24583.1 - 0.054 13.2 3.3 0.12 12.1 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) PTPlike_phytase PF14566.6 CAR24583.1 - 0.065 13.3 2.8 0.14 12.3 2.8 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF2115 PF09888.9 CAR24583.1 - 0.18 12.3 3.2 0.4 11.2 3.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) PDT PF00800.18 CAR24584.1 - 3.4e-54 183.5 0.0 4.5e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 CAR24584.1 - 0.036 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 ACT domain zf-rbx1 PF12678.7 CAR24585.1 - 1.1e-23 83.3 13.9 1.5e-23 82.8 13.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR24585.1 - 1.2e-17 63.7 10.6 1.5e-17 63.4 10.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CAR24585.1 - 1.4e-06 28.5 14.1 6.7e-05 23.1 14.1 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR24585.1 - 0.00023 21.0 15.2 0.063 13.1 15.2 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR24585.1 - 0.0016 18.3 12.4 0.0093 15.8 12.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR24585.1 - 0.0027 17.4 1.1 0.0027 17.4 1.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-Nse PF11789.8 CAR24585.1 - 0.053 13.4 2.7 0.1 12.4 2.7 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CAR24585.1 - 0.072 13.1 8.0 0.24 11.4 8.0 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CAR24585.1 - 0.35 11.1 6.6 0.52 10.5 0.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CAR24585.1 - 0.67 9.6 15.1 54 3.5 15.1 2.3 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CAR24585.1 - 0.68 10.1 10.5 3 8.1 10.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 CAR24585.1 - 1.1 9.3 11.0 4.7 7.3 11.0 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAR24585.1 - 1.8 8.5 12.1 24 4.9 0.4 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CAR24585.1 - 4.8 7.6 12.4 48 4.4 12.4 2.2 1 1 0 1 1 1 0 RING-like domain Med7 PF05983.11 CAR24586.1 - 7.9e-66 221.8 0.4 9.6e-66 221.5 0.4 1.1 1 0 0 1 1 1 1 MED7 protein Med4 PF10018.9 CAR24586.1 - 0.019 14.7 0.7 0.036 13.7 0.6 1.5 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CREPT PF16566.5 CAR24586.1 - 0.044 13.9 1.7 0.065 13.4 0.2 1.9 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Spc42p PF11544.8 CAR24586.1 - 0.24 11.4 2.0 0.41 10.7 0.1 2.2 3 0 0 3 3 3 0 Spindle pole body component Spc42p 6PF2K PF01591.18 CAR24587.1 - 1e-53 182.0 0.0 1.5e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CAR24587.1 - 2.5e-06 27.7 0.0 5.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CAR24587.1 - 8.9e-06 25.3 0.0 2.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 CAR24587.1 - 0.019 15.4 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CAR24587.1 - 0.036 13.3 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 CAR24587.1 - 0.038 14.5 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NUC129 PF08157.11 CAR24587.1 - 0.044 14.1 0.1 0.14 12.6 0.1 1.8 1 0 0 1 1 1 0 NUC129 domain APS_kinase PF01583.20 CAR24587.1 - 0.046 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 CAR24587.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CAR24587.1 - 0.1 12.9 0.0 0.42 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 CAR24588.1 - 3.3e-28 97.4 22.6 1.5e-06 28.8 1.2 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR24588.1 - 1.8e-19 69.8 0.2 0.0059 16.9 0.0 6.4 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR24588.1 - 0.0014 18.6 1.8 0.012 15.5 0.9 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR24588.1 - 0.0035 16.3 3.9 0.97 8.3 0.0 4.2 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CAR24588.1 - 0.032 13.6 0.1 7 5.9 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain MFS_1 PF07690.16 CAR24589.1 - 1.7e-23 83.1 43.2 9.2e-20 70.9 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 CAR24590.1 - 1.5e-10 41.4 6.4 0.0018 19.0 0.1 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CAR24590.1 - 2.6e-10 39.8 5.2 2.6e-10 39.8 5.2 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type DUF1319 PF07028.11 CAR24590.1 - 0.061 13.5 1.2 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1319) VHS PF00790.19 CAR24590.1 - 0.12 12.2 0.1 0.46 10.3 0.1 1.9 1 0 0 1 1 1 0 VHS domain AstE_AspA PF04952.14 CAR24590.1 - 0.21 10.6 0.0 0.39 9.7 0.0 1.4 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family zf-RING_2 PF13639.6 CAR24590.1 - 0.3 11.4 14.3 0.025 14.9 8.5 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.6 CAR24590.1 - 0.87 9.5 9.0 2.2 8.2 9.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 CAR24590.1 - 0.88 9.8 8.4 1.8 8.8 3.3 2.9 1 1 1 2 2 2 0 Zinc-ribbon like family zf-rbx1 PF12678.7 CAR24590.1 - 1.2 9.4 10.9 3.1 8.1 10.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CAR24590.1 - 7.2 6.6 11.2 0.47 10.4 5.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hydrolase_4 PF12146.8 CAR24591.1 - 2.6e-16 59.6 0.0 1.3e-08 34.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAR24591.1 - 1.9e-11 44.1 0.1 1.3e-05 24.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CAR24591.1 - 0.00014 21.4 0.0 0.0004 19.9 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 CAR24591.1 - 0.00057 19.6 0.0 0.0012 18.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CAR24591.1 - 0.0015 19.2 0.0 0.0075 16.9 0.0 2.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family DUF829 PF05705.14 CAR24591.1 - 0.0073 16.2 0.0 1.9 8.3 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF829) BAAT_C PF08840.11 CAR24591.1 - 0.0076 16.2 0.0 0.61 10.0 0.0 2.4 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 CAR24591.1 - 0.028 14.0 0.0 0.19 11.3 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family LIP PF03583.14 CAR24591.1 - 0.053 12.8 0.2 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase DUF818 PF05677.12 CAR24591.1 - 0.083 11.8 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) IF4E PF01652.18 CAR24592.1 - 1.1e-54 184.5 0.4 1.3e-54 184.3 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Na_Ca_ex PF01699.24 CAR24593.1 - 1.1e-24 87.1 32.8 1.7e-17 63.8 10.4 3.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YccF PF03733.13 CAR24593.1 - 3e-10 40.7 6.4 3e-10 40.7 6.4 5.1 5 0 0 5 5 5 1 Inner membrane component domain KRE1 PF17056.5 CAR24594.1 - 2.4e-23 81.6 9.7 2.4e-23 81.6 9.7 3.8 2 1 0 2 2 2 1 Killer toxin-resistance protein 1 TFIIA PF03153.13 CAR24594.1 - 3.9 7.4 6.2 4.4 7.2 6.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1388 PF07142.12 CAR24594.1 - 9.4 6.3 7.2 2.8 8.0 0.7 2.7 2 1 1 3 3 3 0 Repeat of unknown function (DUF1388) Aminotran_3 PF00202.21 CAR24595.1 - 6.8e-119 397.1 0.0 8.5e-119 396.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CDC50 PF03381.15 CAR24596.1 - 2.7e-83 279.7 0.1 3.6e-83 279.3 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1218 PF06749.12 CAR24596.1 - 0.083 13.4 0.1 4.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF4389 PF14333.6 CAR24596.1 - 0.87 9.6 4.4 1.1 9.2 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) DUF3533 PF12051.8 CAR24597.1 - 5.6e-136 453.4 10.4 6.6e-136 453.2 10.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 CAR24597.1 - 0.017 15.0 0.2 0.017 15.0 0.2 2.6 3 0 0 3 3 3 0 CDR ABC transporter DUF4766 PF15973.5 CAR24597.1 - 0.058 14.0 0.1 0.11 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4766) DUF3810 PF12725.7 CAR24597.1 - 0.12 11.7 0.1 0.12 11.7 0.1 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3810) LCM PF04072.14 CAR24598.1 - 2.4e-22 79.8 0.0 4e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 CAR24598.1 - 7.9e-15 54.6 6.3 1.4e-07 31.4 0.0 5.8 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CAR24598.1 - 2.1e-09 37.4 0.9 0.0017 18.6 0.0 4.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CAR24598.1 - 4.9e-08 33.0 4.9 0.00043 20.5 0.1 5.5 4 1 1 5 5 5 1 Kelch motif Kelch_5 PF13854.6 CAR24598.1 - 2.3e-06 27.4 0.1 0.069 13.2 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 CAR24598.1 - 0.23 11.0 7.9 18 5.0 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Syja_N PF02383.18 CAR24599.1 - 1.5e-79 267.6 0.2 2.7e-79 266.8 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain DUF2423 PF10338.9 CAR24599.1 - 0.045 14.0 2.7 0.073 13.3 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2423) KH_6 PF15985.5 CAR24600.1 - 9.7e-13 48.3 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CAR24600.1 - 5.3e-07 29.5 0.0 9.8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain E1_UFD PF09358.10 CAR24600.1 - 0.0086 16.8 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin fold domain DHHC PF01529.20 CAR24601.1 - 1.9e-34 118.6 11.6 1.9e-34 118.6 11.6 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase FtsK_alpha PF17854.1 CAR24602.1 - 0.056 13.6 0.1 5.6 7.2 0.0 2.7 1 1 1 2 2 2 0 FtsK alpha domain HMMR_N PF15905.5 CAR24602.1 - 2.4 7.5 7.0 5.5 6.4 7.0 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DnaJ PF00226.31 CAR24603.1 - 0.0076 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain AAA PF00004.29 CAR24604.1 - 3.3e-54 182.8 0.0 3e-44 150.6 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR24604.1 - 1.1e-13 50.7 0.1 3.5e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CAR24604.1 - 1e-05 26.0 0.2 0.019 15.3 0.0 3.5 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CAR24604.1 - 0.00011 22.0 0.0 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 CAR24604.1 - 0.00025 20.2 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 CAR24604.1 - 0.00095 19.3 0.0 0.004 17.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CAR24604.1 - 0.0015 18.7 0.0 0.44 10.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CAR24604.1 - 0.0019 18.5 0.0 0.036 14.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.10 CAR24604.1 - 0.0024 17.9 0.5 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 CAR24604.1 - 0.0034 17.8 0.0 0.014 15.8 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CAR24604.1 - 0.0034 17.9 0.0 0.11 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CAR24604.1 - 0.0074 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 CAR24604.1 - 0.0089 15.6 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CAR24604.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 CAR24604.1 - 0.014 15.7 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CAR24604.1 - 0.017 14.5 0.1 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAR24604.1 - 0.02 14.9 0.0 0.065 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 CAR24604.1 - 0.028 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 CAR24604.1 - 0.037 14.0 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CAR24604.1 - 0.095 12.7 0.0 0.49 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAR24604.1 - 0.096 12.2 0.2 1.2 8.7 0.1 2.4 2 1 1 3 3 3 0 AAA domain PhoH PF02562.16 CAR24604.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Hist_deacetyl PF00850.19 CAR24605.1 - 2e-83 280.4 0.0 3.7e-83 279.5 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain DMRL_synthase PF00885.19 CAR24606.1 - 2.1e-51 173.4 0.2 2.5e-51 173.2 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2390 PF09523.10 CAR24606.1 - 0.087 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) RRM_1 PF00076.22 CAR24607.1 - 0.00014 21.6 0.6 0.00037 20.3 0.6 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_9 PF18444.1 CAR24607.1 - 0.15 11.9 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif TPR_2 PF07719.17 CAR24608.1 - 1.5e-30 102.8 20.8 0.00076 19.4 0.0 13.2 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_1 PF00515.28 CAR24608.1 - 1e-29 101.1 14.3 1.4e-05 24.7 0.0 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24608.1 - 6.3e-23 80.9 8.1 0.00035 20.8 0.7 9.6 7 2 1 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAR24608.1 - 3.9e-17 62.6 0.3 0.0012 19.5 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR24608.1 - 2.2e-16 59.1 0.8 0.013 16.3 0.0 10.3 8 3 4 12 12 11 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAR24608.1 - 7e-16 58.5 5.2 0.016 15.7 0.0 10.2 10 1 2 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAR24608.1 - 8.7e-15 53.6 20.1 0.019 15.1 0.0 11.8 12 1 1 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAR24608.1 - 1.4e-12 46.7 12.6 0.013 15.4 0.0 9.6 12 0 0 12 12 12 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR24608.1 - 3.8e-12 46.3 17.1 0.00046 20.4 0.0 7.8 5 3 3 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CAR24608.1 - 2.3e-09 37.0 7.7 3.9 8.1 0.0 10.2 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR24608.1 - 8.2e-08 31.8 9.7 0.059 13.1 0.0 8.6 10 0 0 10 10 10 2 TPR repeat TPR_6 PF13174.6 CAR24608.1 - 1.4e-07 31.6 8.8 3 8.7 0.0 11.5 13 0 0 13 13 12 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAR24608.1 - 1.9e-05 24.3 18.0 0.038 13.9 0.0 8.9 11 0 0 11 11 11 2 Tetratricopeptide repeat PPR PF01535.20 CAR24608.1 - 0.0047 17.1 1.0 18 5.8 0.1 5.0 4 0 0 4 4 3 0 PPR repeat LRR_9 PF14580.6 CAR24608.1 - 0.19 11.2 2.8 0.2 11.2 0.9 2.0 2 0 0 2 2 2 0 Leucine-rich repeat Sld5 PF05916.11 CAR24609.1 - 3.3e-17 62.9 0.0 4.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein PEX11 PF05648.14 CAR24610.1 - 1e-60 205.0 2.0 1.2e-60 204.8 2.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Spt20 PF12090.8 CAR24611.1 - 1.4e-70 237.6 3.2 1.4e-70 237.6 3.2 3.3 3 0 0 3 3 3 1 Spt20 family SEP PF08059.13 CAR24611.1 - 0.082 13.5 0.9 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 SEP domain DCP1 PF06058.13 CAR24612.1 - 7.1e-24 84.0 0.0 5.2e-23 81.2 0.0 2.0 1 1 0 1 1 1 1 Dcp1-like decapping family SSF PF00474.17 CAR24613.1 - 3.9e-17 62.2 25.0 3.9e-17 62.2 25.0 1.8 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2045 PF09741.9 CAR24613.1 - 0.038 13.4 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2045) SLATT_fungal PF18142.1 CAR24613.1 - 1 9.4 5.5 0.16 12.0 0.2 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Globin PF00042.22 CAR24614.1 - 1.7e-07 31.8 0.0 8e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Globin Flocculin PF00624.18 CAR24615.1 - 6.6e-169 548.0 438.4 1.6e-15 57.0 22.4 19.8 19 2 0 19 19 19 15 Flocculin repeat Candida_ALS_N PF11766.8 CAR24615.1 - 6.3e-55 186.1 6.1 6.3e-55 186.1 6.1 2.4 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Big_8 PF17961.1 CAR24615.1 - 4.2e-06 26.8 0.0 4.2e-06 26.8 0.0 4.0 3 0 0 3 3 3 1 Bacterial Ig domain DUF4221 PF13970.6 CAR24615.1 - 0.17 11.4 2.7 0.31 10.6 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) Lant_dehydr_C PF14028.6 CAR24615.1 - 7.3 6.0 8.7 22 4.4 0.4 3.5 1 1 2 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term Pectate_lyase PF03211.13 CAR24616.1 - 6.1e-77 257.8 4.8 7.1e-77 257.5 4.8 1.0 1 0 0 1 1 1 1 Pectate lyase Methyltransf_25 PF13649.6 CAR24617.1 - 1e-12 48.5 0.0 2.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR24617.1 - 1.6e-12 47.9 0.0 4.6e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR24617.1 - 1.5e-08 35.3 0.0 2.7e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR24617.1 - 3.2e-08 33.5 0.0 4.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR24617.1 - 2.8e-06 27.2 0.0 5.2e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR24617.1 - 0.00024 20.5 0.0 0.00036 20.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CAR24617.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Rap1a PF18602.1 CAR24617.1 - 0.038 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Rap1a immunity proteins MFS_1 PF07690.16 CAR24618.1 - 7.4e-09 35.0 37.3 1.2e-07 31.1 37.3 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sir1 PF11603.8 CAR24619.1 - 4.6e-24 85.2 1.0 4.6e-24 85.2 1.0 1.9 2 0 0 2 2 2 1 Regulatory protein Sir1 Cys_Met_Meta_PP PF01053.20 CAR24620.1 - 3.4e-28 98.3 0.0 9.2e-28 96.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CAR24620.1 - 0.00056 19.2 0.0 0.00087 18.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Hexokinase_2 PF03727.16 CAR24621.1 - 9.8e-76 254.3 0.0 1.7e-75 253.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CAR24621.1 - 3e-74 249.2 0.0 4e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF2294 PF10057.9 CAR24621.1 - 0.15 12.2 0.2 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) CSN8_PSD8_EIF3K PF10075.9 CAR24622.1 - 4.1e-19 69.0 0.1 6.7e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CAR24622.1 - 8.7e-05 22.0 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family Ppx-GppA PF02541.16 CAR24623.1 - 7.8e-70 235.5 0.0 1e-69 235.2 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family DUF2420 PF10336.9 CAR24624.1 - 2e-32 111.4 0.1 3.2e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 CAR24625.1 - 2.8e-11 43.3 0.2 4.7e-11 42.6 0.2 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAR24625.1 - 6.7e-11 42.3 2.2 1.7e-10 41.0 2.2 1.7 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Proteasome PF00227.26 CAR24626.1 - 5.8e-27 94.4 0.0 7.1e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit IFT81_CH PF18383.1 CAR24626.1 - 0.0085 16.4 0.1 3 8.1 0.0 2.2 2 0 0 2 2 2 2 Intraflagellar transport 81 calponin homology domain PDEase_II PF02112.15 CAR24627.1 - 7.2e-66 222.6 0.0 1.1e-65 222.0 0.0 1.3 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 CAR24627.1 - 0.0001 21.9 0.0 0.00025 20.6 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain S36_mt PF10937.8 CAR24628.1 - 3.8e-25 89.7 0.0 4.8e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Brr6_like_C_C PF10104.9 CAR24629.1 - 5.7e-42 142.6 1.6 7.1e-42 142.3 1.6 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Aldo_ket_red PF00248.21 CAR24630.1 - 5.2e-42 144.0 0.0 1.2e-40 139.5 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RAI1 PF08652.11 CAR24631.1 - 5.5e-25 87.3 0.1 1.2e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease tRNA-synt_1c PF00749.21 CAR24632.1 - 4.2e-120 400.4 0.1 5.7e-120 399.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CAR24632.1 - 1.6e-37 129.0 0.8 3.4e-37 128.0 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 CAR24632.1 - 3.1e-12 46.7 0.2 3.1e-12 46.7 0.2 2.5 2 0 0 2 2 2 1 Glutamate--tRNA ligase N-terminal domain GST_C_2 PF13410.6 CAR24632.1 - 0.01 15.8 0.0 0.04 13.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CAR24632.1 - 0.018 15.2 0.0 0.046 13.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 CAR24632.1 - 0.059 12.7 0.3 0.17 11.2 0.1 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DUF155 PF02582.14 CAR24633.1 - 8.9e-54 182.2 0.1 1.5e-53 181.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SecG PF03840.14 CAR24633.1 - 0.026 14.6 0.4 0.064 13.4 0.4 1.6 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Plus-3 PF03126.18 CAR24634.1 - 9.8e-29 100.1 0.1 2.6e-28 98.7 0.1 1.8 1 0 0 1 1 1 1 Plus-3 domain A_deamin PF02137.18 CAR24635.1 - 6.8e-31 107.9 0.0 1e-30 107.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ank PF00023.30 CAR24636.1 - 8.7e-09 35.4 0.1 0.0084 16.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CAR24636.1 - 1.3e-08 34.4 0.1 0.013 16.0 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CAR24636.1 - 2.1e-05 25.0 0.0 3.9e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR24636.1 - 0.0016 19.0 0.0 0.0057 17.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR24636.1 - 0.01 16.1 0.1 3.3 8.1 0.0 3.3 3 1 0 3 3 3 0 Ankyrin repeats (many copies) FATC PF02260.20 CAR24636.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 FATC domain IBN_N PF03810.19 CAR24637.1 - 3.5e-06 26.8 0.9 0.0018 18.2 0.0 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain TAF6_C PF07571.13 CAR24637.1 - 0.12 12.8 0.2 2.2 8.6 0.0 3.0 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Xpo1 PF08389.12 CAR24637.1 - 0.39 10.8 0.1 0.39 10.8 0.1 5.1 3 2 2 6 6 6 0 Exportin 1-like protein DUF5344 PF17279.2 CAR24637.1 - 4.5 7.9 7.6 6 7.5 0.6 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5344) QRPTase_C PF01729.19 CAR24638.1 - 2.2e-60 203.3 0.0 2.9e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CAR24638.1 - 1e-17 63.9 0.0 3.3e-17 62.3 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IMPDH PF00478.25 CAR24638.1 - 0.01 14.8 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CAR24638.1 - 0.041 12.9 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ANAPC10 PF03256.16 CAR24639.1 - 7.5e-41 139.8 0.0 9.4e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CAR24639.1 - 0.00029 20.9 0.2 0.0011 19.1 0.1 2.0 2 1 0 2 2 2 1 F5/8 type C domain Cse1 PF08506.10 CAR24640.1 - 8.7e-165 548.0 2.4 8.7e-165 548.0 2.4 2.3 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 CAR24640.1 - 1.5e-110 369.7 2.5 2.4e-110 369.1 2.5 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CAR24640.1 - 3e-14 52.7 0.0 9.1e-13 47.9 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CAR24640.1 - 0.011 15.8 0.7 0.12 12.4 0.0 3.3 3 1 0 3 3 3 0 Exportin 1-like protein IFRD PF05004.13 CAR24640.1 - 0.034 13.3 0.1 0.41 9.7 0.0 2.5 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) UTP15_C PF09384.10 CAR24640.1 - 0.093 12.4 0.2 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 UTP15 C terminal CBFB_NFYA PF02045.15 CAR24641.1 - 2.3e-27 95.4 8.7 5.1e-27 94.3 8.7 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GIDA PF01134.22 CAR24643.1 - 3.4e-154 513.7 0.0 4.2e-154 513.4 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CAR24643.1 - 1.8e-64 217.8 0.0 2.5e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 CAR24643.1 - 6.3e-06 25.8 0.9 8.9e-06 25.3 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CAR24643.1 - 8.5e-06 25.2 3.9 0.00013 21.3 4.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CAR24643.1 - 0.01 14.9 3.4 0.01 14.9 3.4 2.5 4 0 0 4 4 4 0 FAD binding domain Pyr_redox PF00070.27 CAR24643.1 - 0.031 14.8 0.3 0.069 13.7 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CAR24643.1 - 0.042 13.1 0.3 0.09 12.1 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CAR24643.1 - 0.14 11.4 0.1 0.6 9.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CAR24643.1 - 0.15 11.6 4.5 7.6 6.0 2.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CAR24643.1 - 1.9 7.1 5.6 5.7 5.5 1.6 2.7 3 0 0 3 3 3 0 HI0933-like protein GARS_A PF01071.19 CAR24644.1 - 2.5e-81 272.1 0.0 4.2e-81 271.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CAR24644.1 - 3.6e-33 114.2 0.3 1.1e-32 112.6 0.1 2.0 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CAR24644.1 - 4.6e-33 114.6 0.0 1.1e-32 113.3 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CAR24644.1 - 2.3e-27 95.1 0.3 7.6e-27 93.4 0.3 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CAR24644.1 - 3e-16 59.8 5.4 9.7e-16 58.2 3.3 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 CAR24644.1 - 3.2e-08 33.3 0.0 6.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CAR24644.1 - 3e-06 26.9 0.1 8.2e-06 25.5 0.1 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CAR24644.1 - 1.4e-05 25.2 0.0 4.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_2 PF08442.10 CAR24644.1 - 0.0029 17.2 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CAR24644.1 - 0.025 14.2 0.0 0.069 12.7 0.0 1.7 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 CAR24644.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 CAR24644.1 - 0.1 11.8 0.0 0.29 10.3 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Mito_carr PF00153.27 CAR24645.1 - 3.9e-38 129.3 7.8 2.2e-18 66.0 0.2 4.5 2 2 1 3 3 3 3 Mitochondrial carrier protein Lipoxygenase PF00305.19 CAR24645.1 - 0.081 11.3 0.1 0.11 10.9 0.1 1.1 1 0 0 1 1 1 0 Lipoxygenase Serine_protease PF18405.1 CAR24645.1 - 0.1 11.8 1.2 0.78 8.8 0.0 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Peptidase_M20 PF01546.28 CAR24646.1 - 1.2e-29 103.5 0.0 1.7e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR24646.1 - 1.4e-09 37.9 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR24646.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 DUF848 PF05852.11 CAR24646.1 - 0.13 12.3 0.0 0.58 10.3 0.0 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Sec15 PF04091.12 CAR24647.1 - 2.6e-98 329.3 5.5 2.6e-98 329.3 5.5 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like THUMP PF02926.17 CAR24648.1 - 6.9e-25 87.8 0.3 1.1e-24 87.1 0.3 1.3 1 0 0 1 1 1 1 THUMP domain APC_r PF05923.12 CAR24648.1 - 0.48 10.2 2.7 1.3 8.9 1.1 2.3 2 0 0 2 2 2 0 APC repeat DUF1077 PF06417.12 CAR24649.1 - 3.2e-42 143.3 6.3 4e-42 143.0 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) VPS13_C PF16909.5 CAR24649.1 - 0.0042 16.9 0.0 0.0056 16.5 0.0 1.2 1 0 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal SdpI PF13630.6 CAR24650.1 - 0.09 12.9 0.4 14 5.9 0.0 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family Adaptin_binding PF10199.9 CAR24651.1 - 0.00023 21.7 0.4 0.29 11.7 0.1 2.3 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 DnaJ PF00226.31 CAR24652.1 - 8.1e-15 54.7 5.9 1e-14 54.4 4.8 1.8 2 0 0 2 2 2 1 DnaJ domain SAPS PF04499.15 CAR24653.1 - 3.1e-165 550.7 15.1 9.9e-165 549.0 15.1 1.8 1 1 0 1 1 1 1 SIT4 phosphatase-associated protein ZYG-11_interact PF05884.12 CAR24654.1 - 0.39 10.1 1.6 0.76 9.1 0.1 2.1 2 0 0 2 2 2 0 Interactor of ZYG-11 ApoO PF09769.9 CAR24654.1 - 8.3 6.4 5.9 43 4.1 0.0 3.2 3 0 0 3 3 3 0 Apolipoprotein O AdoHcyase PF05221.17 CAR24655.1 - 1.1e-129 431.9 0.0 1.3e-125 418.5 0.0 2.0 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CAR24655.1 - 1.3e-84 282.2 1.4 2.1e-84 281.5 1.4 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CAR24655.1 - 5.8e-07 29.0 0.0 1.1e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CAR24655.1 - 0.0011 18.6 0.1 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CAR24655.1 - 0.0061 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain DUF2572 PF10833.8 CAR24655.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) SPRY PF00622.28 CAR24656.1 - 3.7e-29 101.3 0.3 1e-28 99.8 0.3 1.8 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.9 CAR24656.1 - 3e-16 59.6 1.7 6.2e-16 58.6 1.7 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain GP40 PF11025.8 CAR24656.1 - 0.0092 15.8 1.4 0.018 14.8 1.4 1.4 1 0 0 1 1 1 1 Glycoprotein GP40 of Cryptosporidium DUF2457 PF10446.9 CAR24656.1 - 0.061 12.5 24.3 0.13 11.4 24.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 CAR24656.1 - 0.46 8.6 22.6 0.73 8.0 22.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CAR24656.1 - 0.79 7.9 16.3 1.2 7.3 16.3 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 CAR24656.1 - 3 7.4 14.6 6 6.4 14.6 1.5 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 CAR24656.1 - 3.8 6.8 23.1 6.3 6.1 23.1 1.3 1 0 0 1 1 1 0 SDA1 Drc1-Sld2 PF11719.8 CAR24656.1 - 7.9 5.9 13.1 14 5.1 13.1 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Ost5 PF05251.12 CAR24657.1 - 2.6e-11 43.6 9.9 3.2e-11 43.3 9.9 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 COX4 PF02936.14 CAR24658.1 - 3.9e-11 43.1 0.1 5.3e-11 42.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV SHR3_chaperone PF08229.11 CAR24658.1 - 0.14 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 PMSR PF01625.21 CAR24659.1 - 1.1e-53 181.5 1.0 1.4e-53 181.2 1.0 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3889 PF13028.6 CAR24659.1 - 0.019 14.9 1.6 0.083 12.8 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3889) XPG_I PF00867.18 CAR24660.1 - 1.2e-23 83.2 0.0 3.2e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CAR24660.1 - 0.00017 22.0 0.0 0.00036 21.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CAR24660.1 - 0.0093 15.5 0.0 0.069 12.6 0.0 2.2 2 0 0 2 2 2 1 XPG domain containing GATA PF00320.27 CAR24661.1 - 2e-14 52.9 3.8 3.7e-14 52.0 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CAR24661.1 - 0.19 11.3 0.5 0.34 10.5 0.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding MRNIP PF15749.5 CAR24661.1 - 7.1 7.4 8.4 1.8 9.3 0.2 2.9 2 0 0 2 2 2 0 MRN-interacting protein EamA PF00892.20 CAR24662.1 - 5e-08 33.2 31.1 0.00015 21.9 9.8 2.1 2 0 0 2 2 2 2 EamA-like transporter family TRAP-gamma PF07074.12 CAR24662.1 - 0.04 13.5 0.4 0.04 13.5 0.4 2.3 1 1 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Multi_Drug_Res PF00893.19 CAR24662.1 - 1.7 9.4 13.6 9.6 7.0 0.5 3.2 2 1 1 3 3 3 0 Small Multidrug Resistance protein Nse5 PF08691.10 CAR24663.1 - 2.6e-15 56.1 0.1 5e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 HAD_2 PF13419.6 CAR24664.1 - 6.9e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR24664.1 - 5.2e-07 30.2 0.0 4.9e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase N_formyltrans_C PF18216.1 CAR24664.1 - 0.028 14.1 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Vps51 PF08700.11 CAR24665.1 - 0.051 13.7 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Vps51/Vps67 Lin-8 PF03353.15 CAR24665.1 - 1.4 8.4 9.2 2.6 7.5 9.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.7 CAR24665.1 - 1.8 6.6 10.6 2.8 6.0 10.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOG2 PF10428.9 CAR24665.1 - 4.1 6.5 18.3 0.54 9.4 14.0 1.7 2 0 0 2 2 2 0 RAM signalling pathway protein DUF1387 PF07139.11 CAR24665.1 - 5.1 6.7 11.5 11 5.6 11.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) ABC_tran PF00005.27 CAR24667.1 - 4.7e-49 166.4 0.1 6.5e-24 85.0 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CAR24667.1 - 7.6e-22 77.2 0.9 7.6e-22 77.2 0.9 3.3 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 CAR24667.1 - 6.5e-19 68.9 0.5 8.2e-06 25.8 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR24667.1 - 2.3e-10 40.3 2.8 0.17 11.3 0.1 4.8 3 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CAR24667.1 - 1.1e-07 32.0 0.6 0.00013 21.9 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 CAR24667.1 - 8e-07 28.7 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CAR24667.1 - 2.5e-06 27.6 0.1 0.003 17.6 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CAR24667.1 - 5.5e-06 26.7 0.1 0.15 12.4 0.0 3.3 3 0 0 3 3 2 2 RNA helicase AAA PF00004.29 CAR24667.1 - 6.5e-06 26.6 0.0 0.041 14.3 0.0 3.7 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CAR24667.1 - 9.1e-06 25.7 1.2 0.17 11.8 0.0 3.1 4 0 0 4 4 2 2 NACHT domain AAA_22 PF13401.6 CAR24667.1 - 1.1e-05 25.7 0.0 0.18 12.1 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAR24667.1 - 1.7e-05 25.3 0.1 0.034 14.5 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CAR24667.1 - 1.8e-05 25.3 0.0 0.11 13.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 CAR24667.1 - 3.9e-05 24.3 10.2 0.03 14.8 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 CAR24667.1 - 9.3e-05 22.3 4.4 0.053 13.2 0.0 3.1 4 0 0 4 4 3 2 AAA ATPase domain AAA_24 PF13479.6 CAR24667.1 - 0.00011 22.0 0.2 0.48 10.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 CAR24667.1 - 0.00011 22.5 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CAR24667.1 - 0.00012 22.1 0.0 0.28 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CAR24667.1 - 0.00016 21.9 1.3 0.51 10.5 0.0 3.1 4 0 0 4 4 2 2 AAA domain TsaE PF02367.17 CAR24667.1 - 0.00058 19.9 0.4 1 9.4 0.0 3.5 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CAR24667.1 - 0.00087 19.3 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 CAR24667.1 - 0.00095 18.4 0.0 0.27 10.4 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain MCM PF00493.23 CAR24667.1 - 0.0016 17.6 0.0 0.6 9.2 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain Roc PF08477.13 CAR24667.1 - 0.0018 18.5 0.0 1.3 9.3 0.0 3.0 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CAR24667.1 - 0.0022 18.0 0.1 2.2 8.3 0.1 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CAR24667.1 - 0.004 16.7 0.0 0.57 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 CAR24667.1 - 0.0072 15.9 0.0 2.1 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain VirE PF05272.11 CAR24667.1 - 0.01 15.5 0.1 0.95 9.1 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E AAA_17 PF13207.6 CAR24667.1 - 0.011 16.2 2.4 2.4 8.6 0.0 3.6 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 CAR24667.1 - 0.011 14.8 0.0 0.053 12.6 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 CAR24667.1 - 0.013 14.5 0.0 1.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CAR24667.1 - 0.021 14.9 1.6 7.6 6.5 0.1 3.1 3 1 0 3 3 2 0 Helicase HerA, central domain AAA_27 PF13514.6 CAR24667.1 - 0.021 14.4 0.0 9.4 5.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CAR24667.1 - 0.027 13.7 0.3 3.4 6.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.20 CAR24667.1 - 0.034 13.3 0.1 1.9 7.5 0.0 2.6 3 0 0 3 3 3 0 G-protein alpha subunit NTPase_1 PF03266.15 CAR24667.1 - 0.041 13.8 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 NTPase Septin PF00735.18 CAR24667.1 - 0.043 13.1 0.2 12 5.1 0.0 2.6 3 0 0 3 3 2 0 Septin KAP_NTPase PF07693.14 CAR24667.1 - 0.045 13.0 0.8 13 4.9 0.0 3.3 3 0 0 3 3 3 0 KAP family P-loop domain AAA_30 PF13604.6 CAR24667.1 - 0.047 13.4 2.7 0.9 9.2 0.2 3.7 4 1 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 CAR24667.1 - 0.057 13.2 0.0 0.61 9.8 0.0 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 CAR24667.1 - 0.077 12.7 0.1 0.8 9.4 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain dNK PF01712.19 CAR24667.1 - 0.091 12.6 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase FeoB_N PF02421.18 CAR24667.1 - 0.093 12.3 0.0 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 CAR24667.1 - 0.22 11.1 2.0 7.4 6.1 0.0 3.4 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 CAR24667.1 - 0.23 11.7 0.8 18 5.6 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 CAR24667.1 - 0.4 10.7 7.2 17 5.4 0.0 4.1 4 1 1 5 5 4 0 Dynamin family ATPase_2 PF01637.18 CAR24667.1 - 1.7 8.5 6.0 19 5.1 0.0 3.3 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea RtcB PF01139.17 CAR24667.1 - 4.5 6.4 5.8 0.93 8.6 2.5 1.5 2 0 0 2 2 1 0 tRNA-splicing ligase RtcB DUF5583 PF17821.1 CAR24668.1 - 0.087 12.8 1.4 0.17 11.9 0.3 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5583) DUF5364 PF17322.2 CAR24669.1 - 1.6e-54 185.1 5.6 1.9e-54 184.8 5.6 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5364) NIF3 PF01784.18 CAR24670.1 - 2.2e-67 227.3 0.0 2.7e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 CAR24671.1 - 4.6e-16 58.9 0.0 5.5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Oxidored_FMN PF00724.20 CAR24673.1 - 5.7e-128 427.0 0.0 6.6e-128 426.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Kinesin PF00225.23 CAR24674.1 - 1.3e-115 385.9 0.1 2.5e-115 385.0 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAR24674.1 - 6.9e-28 97.5 0.0 2.7e-27 95.5 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Borrelia_REV PF03978.13 CAR24674.1 - 0.00019 21.4 0.2 0.0005 20.1 0.2 1.7 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein AAA_33 PF13671.6 CAR24674.1 - 0.028 14.6 0.1 0.21 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cyclin PF08613.11 CAR24675.1 - 0.0018 18.7 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CAR24675.1 - 0.0066 16.2 0.0 0.014 15.2 0.0 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.32 CAR24676.1 - 1.3e-09 38.4 14.7 6.6e-06 26.8 0.6 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR24676.1 - 2.9e-09 37.1 0.0 0.0014 18.9 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR24676.1 - 0.00022 20.3 0.1 0.57 9.1 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CAR24676.1 - 0.025 14.4 0.2 1.2 9.0 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CAR24676.1 - 0.11 11.1 0.0 0.33 9.6 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PX PF00787.24 CAR24677.1 - 1.3e-11 44.5 0.9 1.8e-11 44.0 0.1 1.7 2 0 0 2 2 2 1 PX domain ATP_bind_3 PF01171.20 CAR24678.1 - 4.2e-18 65.8 0.0 7.3e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CAR24678.1 - 1.4e-16 59.7 6.3 1.4e-16 59.7 6.3 3.6 3 1 0 3 3 3 1 Zinc-ribbon tRNA_Me_trans PF03054.16 CAR24678.1 - 0.001 18.0 0.0 0.0017 17.3 0.0 1.3 1 1 0 1 1 1 1 tRNA methyl transferase Ras PF00071.22 CAR24681.1 - 8.2e-62 207.6 0.4 9.8e-62 207.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24681.1 - 8.2e-35 119.6 0.1 1.3e-34 119.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24681.1 - 7.2e-14 51.6 0.0 9.5e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR24681.1 - 6.8e-07 29.4 0.1 1.2e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR24681.1 - 3.5e-05 23.4 0.1 0.00018 21.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAR24681.1 - 0.00026 20.4 0.0 0.00033 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAR24681.1 - 0.00097 19.1 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase KAP_NTPase PF07693.14 CAR24681.1 - 0.0011 18.2 0.0 0.0023 17.2 0.0 1.4 1 1 0 1 1 1 1 KAP family P-loop domain PduV-EutP PF10662.9 CAR24681.1 - 0.0059 16.4 0.0 0.0087 15.8 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CAR24681.1 - 0.0067 15.9 0.1 0.016 14.7 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CAR24681.1 - 0.012 16.0 0.1 0.022 15.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CAR24681.1 - 0.013 15.8 0.2 0.066 13.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 CAR24681.1 - 0.022 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CAR24681.1 - 0.029 13.9 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAR24681.1 - 0.035 13.8 0.3 0.063 13.0 0.1 1.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CAR24681.1 - 0.035 14.6 0.7 0.059 13.9 0.7 1.6 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 CAR24681.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF1128 PF06569.11 CAR24681.1 - 0.078 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) MCM PF00493.23 CAR24681.1 - 0.11 11.5 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain CHZ PF09649.10 CAR24682.1 - 5.9e-19 67.2 1.4 5.9e-19 67.2 1.4 2.2 2 1 1 3 3 3 1 Histone chaperone domain CHZ LSM PF01423.22 CAR24683.1 - 1.7e-16 59.6 0.0 3.6e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 LSM domain zf-C2H2 PF00096.26 CAR24684.1 - 6.6e-08 32.6 15.7 0.00076 19.8 1.8 2.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR24684.1 - 3.4e-06 27.4 13.0 0.0096 16.7 3.6 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR24684.1 - 4.9e-06 26.7 16.6 0.00048 20.4 4.7 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CAR24684.1 - 0.084 13.2 2.9 0.45 10.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CAR24684.1 - 0.23 11.5 5.9 5.4 7.1 2.4 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger AMPK1_CBM PF16561.5 CAR24685.1 - 2.7e-30 104.4 0.0 5.4e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CAR24685.1 - 2.9e-27 94.8 0.6 2.9e-27 94.8 0.6 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 CAR24685.1 - 0.079 13.5 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) SPT16 PF08644.11 CAR24686.1 - 2.8e-49 167.2 1.8 3e-49 167.1 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 CAR24686.1 - 1.6e-46 158.0 4.0 2.6e-46 157.3 0.0 3.0 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CAR24686.1 - 2.8e-28 99.1 0.0 5e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CAR24686.1 - 1.3e-14 54.4 0.2 2.7e-13 50.1 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Clathrin PF00637.20 CAR24687.1 - 2e-187 614.6 44.6 2.4e-31 108.5 0.0 8.2 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CAR24687.1 - 4.4e-28 97.0 2.4 3.1e-26 91.1 0.2 3.3 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 CAR24687.1 - 6.3e-20 70.4 6.0 0.00028 21.0 0.2 5.8 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.10 CAR24687.1 - 2e-11 43.0 0.9 9.9e-11 40.8 0.2 2.4 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 CAR24687.1 - 0.0005 19.2 7.1 0.82 8.6 0.0 4.3 5 0 0 5 5 5 2 Coatomer WD associated region TPR_1 PF00515.28 CAR24687.1 - 0.091 12.6 8.1 33 4.5 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Vps39_1 PF10366.9 CAR24687.1 - 0.18 12.1 14.9 5.4 7.3 0.0 7.4 7 2 1 8 8 8 0 Vacuolar sorting protein 39 domain 1 PPR PF01535.20 CAR24687.1 - 0.29 11.5 3.0 88 3.7 0.0 5.2 5 1 1 6 6 6 0 PPR repeat TPR_12 PF13424.6 CAR24687.1 - 1.7 9.0 7.4 11 6.4 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat ACOX PF01756.19 CAR24688.1 - 4.7e-47 159.9 0.0 8.8e-47 159.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CAR24688.1 - 1.4e-21 76.5 0.0 2.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CAR24688.1 - 1.4e-09 38.6 0.0 4.7e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CAR24688.1 - 0.0025 18.0 0.0 0.1 12.8 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CDP-OH_P_transf PF01066.21 CAR24689.1 - 4.9e-12 46.4 0.3 4.9e-12 46.4 0.3 1.9 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Peptidase_S10 PF00450.22 CAR24690.1 - 2.8e-103 346.5 0.1 3.4e-103 346.3 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Presenilin PF01080.17 CAR24690.1 - 7.9 5.1 8.1 12 4.5 8.1 1.2 1 0 0 1 1 1 0 Presenilin Aminotran_1_2 PF00155.21 CAR24691.1 - 4.2e-22 78.8 0.0 6.7e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CAR24691.1 - 0.026 13.3 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 CAR24691.1 - 0.24 10.6 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Sugar_tr PF00083.24 CAR24692.1 - 4.9e-42 144.3 18.4 1e-41 143.3 18.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR24692.1 - 2.6e-36 125.3 22.3 2.6e-36 125.3 22.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CAR24692.1 - 0.00013 20.7 11.0 0.0012 17.5 3.2 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein DUF1282 PF06930.12 CAR24692.1 - 0.031 14.0 8.6 0.46 10.2 0.8 3.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1282) Peroxin-3 PF04882.12 CAR24692.1 - 0.12 11.4 0.2 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Peroxin-3 MFS_1_like PF12832.7 CAR24692.1 - 0.97 8.2 12.8 5.7 5.7 2.3 2.2 1 1 1 2 2 2 0 MFS_1 like family Flavi_NS4A PF01350.17 CAR24692.1 - 7.8 6.4 6.6 22 4.9 0.3 2.8 2 2 0 2 2 2 0 Flavivirus non-structural protein NS4A Phosphorylase PF00343.20 CAR24693.1 - 0 1044.7 1.8 0 1044.4 1.8 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Rsa3 PF14615.6 CAR24693.1 - 0.17 11.5 1.3 3.9 7.1 0.0 3.2 3 0 0 3 3 3 0 Ribosome-assembly protein 3 MCM PF00493.23 CAR24694.1 - 1.3e-103 345.0 0.9 1.8e-103 344.5 0.9 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR24694.1 - 5.4e-39 132.9 0.1 1.5e-38 131.5 0.1 1.8 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 CAR24694.1 - 3.8e-31 107.5 0.3 9.6e-31 106.2 0.3 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CAR24694.1 - 2.7e-26 91.8 2.5 3.2e-26 91.5 1.2 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CAR24694.1 - 1.8e-24 86.3 0.3 5.9e-24 84.6 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR24694.1 - 9.7e-07 28.4 0.0 3.8e-06 26.4 0.0 1.9 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CAR24694.1 - 0.0022 17.7 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CAR24694.1 - 0.0026 17.6 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR24694.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RRN3 PF05327.11 CAR24694.1 - 0.18 10.3 0.9 0.36 9.3 0.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SKN1 PF03935.15 CAR24695.1 - 1.4e-250 831.9 4.5 1.7e-250 831.6 4.5 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SIS PF01380.22 CAR24696.1 - 1.1e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 CAR24696.1 - 6.5e-07 29.5 0.0 0.027 14.5 0.0 2.3 1 1 1 2 2 2 2 SIS domain PreAtp-grasp PF18604.1 CAR24696.1 - 0.081 12.6 0.1 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 Pre ATP-grasp domain Rod-binding PF10135.9 CAR24696.1 - 0.15 12.7 2.0 0.2 12.3 0.6 1.9 2 0 0 2 2 2 0 Rod binding protein Borrelia_P83 PF05262.11 CAR24697.1 - 0.3 9.5 30.4 0.45 8.9 30.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC_trans_N PF14510.6 CAR24697.1 - 8.2 7.1 0.0 8.2 7.1 0.0 3.9 3 1 0 3 3 3 0 ABC-transporter N-terminal Vps62 PF06101.11 CAR24698.1 - 3.4e-06 25.7 3.5 1.2e-05 23.9 3.5 1.9 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 NDC10_II PF16787.5 CAR24699.1 - 1e-106 356.6 0.6 1e-106 356.6 0.6 1.9 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CAR24699.1 - 4.8e-21 74.9 0.4 1.1e-20 73.7 0.1 1.9 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Cwf_Cwc_15 PF04889.12 CAR24699.1 - 0.19 11.4 10.0 0.3 10.8 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MCPVI PF02993.14 CAR24699.1 - 3.3 7.5 7.5 11 5.7 7.5 1.9 1 1 0 1 1 1 0 Minor capsid protein VI DUF3461 PF11944.8 CAR24699.1 - 4 7.6 5.5 7.9 6.6 0.2 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3461) MFS_1 PF07690.16 CAR24700.1 - 5.8e-33 114.3 29.2 5.8e-33 114.3 29.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR24700.1 - 2e-12 46.7 16.7 2e-12 46.7 16.7 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter NCA2 PF08637.10 CAR24702.1 - 7.4e-95 317.4 0.5 1.1e-94 316.8 0.5 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 SH3_1 PF00018.28 CAR24703.1 - 2e-14 52.9 0.0 3.3e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR24703.1 - 3.7e-13 49.1 0.0 7.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR24703.1 - 1.4e-09 37.5 0.0 2.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 CAR24703.1 - 1.1 9.2 9.1 1.2 9.1 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CAR24703.1 - 1.2 9.8 18.0 0.66 10.6 15.5 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tmemb_170 PF10190.9 CAR24704.1 - 1.3e-15 57.7 13.7 1.6e-15 57.4 13.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 ABC2_membrane_2 PF12679.7 CAR24704.1 - 0.085 12.1 6.0 0.12 11.6 5.7 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein PDR_CDR PF06422.12 CAR24704.1 - 0.46 10.4 2.8 0.93 9.4 2.8 1.5 1 0 0 1 1 1 0 CDR ABC transporter Proteasome PF00227.26 CAR24705.1 - 1e-57 194.7 0.3 1.3e-57 194.4 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR24705.1 - 2.9e-11 42.8 0.5 5.7e-11 41.9 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WW PF00397.26 CAR24706.1 - 1.8e-10 40.7 7.4 1.1e-06 28.6 5.0 2.8 2 0 0 2 2 2 2 WW domain FF PF01846.19 CAR24706.1 - 8.8e-09 35.4 5.2 1.1e-08 35.1 0.6 3.4 4 0 0 4 4 4 1 FF domain Aldo_ket_red PF00248.21 CAR24707.1 - 3.3e-43 148.0 0.2 6.5e-35 120.8 0.2 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Pullulanase_Ins PF18494.1 CAR24707.1 - 0.02 15.3 0.0 0.04 14.4 0.0 1.4 1 0 0 1 1 1 0 Pullulanase Ins domain Cas_DxTHG PF09455.10 CAR24707.1 - 0.028 14.0 0.4 0.035 13.7 0.4 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Cys_Met_Meta_PP PF01053.20 CAR24707.1 - 0.074 11.6 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CoA_binding PF02629.19 CAR24709.1 - 3.5e-26 91.7 2.0 3.5e-26 91.7 2.0 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CAR24709.1 - 8.8e-23 80.8 0.7 1.5e-22 80.0 0.7 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CAR24709.1 - 4.7e-10 39.4 0.1 9.8e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CAR24709.1 - 1.6e-05 25.4 0.1 4e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 CoA binding domain IlvN PF07991.12 CAR24709.1 - 0.086 12.4 0.7 0.67 9.5 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain TPK_catalytic PF04263.16 CAR24710.1 - 2.1e-31 108.5 0.3 6.4e-31 106.9 0.3 1.7 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CAR24710.1 - 8.5e-13 47.8 0.0 1.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TFIID-18kDa PF02269.16 CAR24711.1 - 5.9e-36 122.4 0.3 2.7e-35 120.3 0.1 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit AAA PF00004.29 CAR24712.1 - 4.2e-05 24.0 0.0 0.00013 22.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CAR24712.1 - 0.0016 18.4 0.1 0.021 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 CAR24712.1 - 0.0069 16.3 0.2 0.021 14.7 0.0 1.8 1 1 1 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 CAR24712.1 - 0.013 15.8 0.1 0.54 10.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain KH_8 PF17903.1 CAR24713.1 - 6.1e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CAR24713.1 - 0.11 12.3 0.2 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 CAR24714.1 - 4.7e-93 312.6 16.4 3.7e-46 157.9 1.5 4.1 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins Lectin_C_term PF18022.1 CAR24714.1 - 1.9 9.0 4.8 25 5.4 0.2 3.2 3 0 0 3 3 3 0 Ricin-type beta-trefoil lectin C-terminal domain G-patch_2 PF12656.7 CAR24715.1 - 1.1e-19 70.2 1.4 2.9e-19 68.9 0.1 2.3 3 0 0 3 3 3 1 G-patch domain Ashwin PF15323.6 CAR24715.1 - 0.0093 16.0 1.6 0.015 15.3 1.6 1.3 1 0 0 1 1 1 1 Developmental protein She9_MDM33 PF05546.11 CAR24716.1 - 1e-87 293.1 15.4 7.9e-87 290.2 10.2 2.2 2 0 0 2 2 2 2 She9 / Mdm33 family Tropomyosin_1 PF12718.7 CAR24716.1 - 0.0022 18.1 3.9 0.0022 18.1 3.9 3.2 3 1 0 3 3 3 1 Tropomyosin like ApoLp-III PF07464.11 CAR24716.1 - 0.0045 17.1 0.8 0.0045 17.1 0.8 3.2 3 1 0 3 3 3 1 Apolipophorin-III precursor (apoLp-III) SKA1 PF07160.12 CAR24716.1 - 0.029 14.2 9.1 0.28 11.0 3.4 2.9 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Phage_Mu_Gam PF07352.12 CAR24716.1 - 0.065 13.1 6.5 0.15 12.0 5.0 2.2 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein PsbH PF00737.20 CAR24716.1 - 0.083 12.6 0.6 0.15 11.8 0.6 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Phi-29_GP16_7 PF06720.11 CAR24716.1 - 0.11 12.4 1.3 0.14 12.0 0.3 1.7 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 DUF948 PF06103.11 CAR24716.1 - 0.23 11.8 2.8 5.6 7.3 0.0 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Dynactin_p62 PF05502.13 CAR24716.1 - 0.25 10.1 6.6 0.51 9.1 0.6 2.1 1 1 1 2 2 2 0 Dynactin p62 family Spectrin PF00435.21 CAR24716.1 - 0.55 10.7 8.0 1.9 9.0 1.0 3.3 3 0 0 3 3 3 0 Spectrin repeat ISG65-75 PF11727.8 CAR24716.1 - 0.57 9.4 9.2 0.8 8.9 2.9 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein Syntaxin PF00804.25 CAR24716.1 - 1.4 8.5 10.3 0.55 9.9 5.6 2.2 2 0 0 2 2 2 0 Syntaxin YscO-like PF16789.5 CAR24716.1 - 2.6 8.1 14.6 1.4 9.0 10.2 2.6 2 1 1 3 3 3 0 YscO-like protein AAA PF00004.29 CAR24717.1 - 1e-45 155.4 0.5 3e-45 153.9 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CAR24717.1 - 2.5e-09 37.0 0.4 1.7e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CAR24717.1 - 1.8e-08 34.7 0.0 3.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CAR24717.1 - 3.3e-07 30.8 0.0 5.3e-05 23.7 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CAR24717.1 - 5.1e-07 29.8 0.1 2.3e-06 27.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR24717.1 - 3.5e-05 24.1 0.7 0.0032 17.8 0.7 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAR24717.1 - 0.00011 22.0 0.0 0.00045 20.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CAR24717.1 - 0.00012 21.3 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TsaE PF02367.17 CAR24717.1 - 0.00058 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CAR24717.1 - 0.0008 18.7 0.0 0.0018 17.6 0.0 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 CAR24717.1 - 0.001 19.6 0.0 0.0047 17.5 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_lid_3 PF17862.1 CAR24717.1 - 0.0011 18.7 0.1 0.0024 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain NTPase_1 PF03266.15 CAR24717.1 - 0.0012 18.8 0.2 0.0045 16.9 0.0 2.1 3 0 0 3 3 2 1 NTPase AAA_24 PF13479.6 CAR24717.1 - 0.0019 17.9 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR24717.1 - 0.0034 17.8 0.0 0.0066 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_3 PF07726.11 CAR24717.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CAR24717.1 - 0.0038 16.7 0.0 0.031 13.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CAR24717.1 - 0.0047 16.7 0.0 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 CAR24717.1 - 0.0048 16.6 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CAR24717.1 - 0.0057 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CAR24717.1 - 0.0066 15.9 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 CAR24717.1 - 0.0075 16.4 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAR24717.1 - 0.0087 15.5 0.1 0.021 14.2 0.0 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CAR24717.1 - 0.012 15.4 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 CAR24717.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR24717.1 - 0.023 14.6 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 CAR24717.1 - 0.032 14.0 0.0 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 CAR24717.1 - 0.037 12.9 0.0 0.091 11.6 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.6 CAR24717.1 - 0.093 13.2 0.9 18 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CAR24717.1 - 0.14 12.5 0.1 0.4 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 CAR24717.1 - 0.17 11.7 2.9 0.4 10.5 0.0 2.6 3 1 0 4 4 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CAR24717.1 - 0.2 11.2 1.5 0.44 10.1 0.1 2.1 2 1 1 3 3 2 0 AAA domain Parvo_NS1 PF01057.17 CAR24717.1 - 0.23 10.5 0.0 0.4 9.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Glyco_transf_22 PF03901.17 CAR24718.1 - 1.4e-67 228.7 26.6 1.7e-67 228.5 26.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family IBN_N PF03810.19 CAR24719.1 - 2.5e-13 49.8 0.2 8.9e-13 48.0 0.2 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 CAR24719.1 - 9.7e-05 21.4 5.3 0.00021 20.2 0.1 3.6 3 1 0 4 4 4 1 Cse1 CBFD_NFYB_HMF PF00808.23 CAR24720.1 - 1.2e-14 54.4 2.2 1.9e-14 53.7 2.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAR24720.1 - 0.014 15.7 0.1 0.014 15.7 0.1 1.9 2 1 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Lig_C PF18330.1 CAR24720.1 - 0.026 14.5 1.3 0.038 14.0 1.3 1.3 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region DUF2960 PF11173.8 CAR24720.1 - 0.056 13.9 0.1 0.1 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Utp12 PF04003.12 CAR24722.1 - 7.4e-22 77.7 1.3 1.4e-21 76.8 1.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 CAR24722.1 - 0.0053 17.6 0.3 2.2 9.3 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 CAR24722.1 - 0.049 12.9 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pribosyltran PF00156.27 CAR24723.1 - 5.3e-10 39.0 0.0 9.1e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain 3Beta_HSD PF01073.19 CAR24723.1 - 0.0038 16.3 0.0 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fe-ADH PF00465.19 CAR24723.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase EC042_2821 PF18740.1 CAR24723.1 - 0.077 12.9 0.5 0.33 10.8 0.1 1.9 1 1 1 2 2 2 0 EC042_2821-lke REase MFS_1 PF07690.16 CAR24724.1 - 1.8e-20 73.2 93.5 2.9e-15 56.0 55.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily IU_nuc_hydro PF01156.19 CAR24726.1 - 5.7e-70 236.3 0.0 6.6e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.22 CAR24727.1 - 7.9e-47 160.1 0.1 3.5e-46 157.9 0.1 1.7 1 1 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.12 CAR24728.1 - 8.8e-95 317.3 0.0 1.2e-94 316.9 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein SHS2_Rpb7-N PF03876.17 CAR24729.1 - 3.2e-18 65.9 0.0 5.5e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CAR24729.1 - 6.7e-13 48.8 0.0 1.1e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 CAR24729.1 - 0.00022 21.5 0.0 0.00042 20.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.18 CAR24730.1 - 6.3e-47 158.9 0.2 8.1e-47 158.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.28 CAR24731.1 - 8.6e-125 416.8 0.1 1.4e-124 416.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAR24731.1 - 3.3e-69 232.5 0.1 5.7e-69 231.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CAR24731.1 - 3.9e-51 173.4 0.0 7.3e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CAR24731.1 - 5.1e-34 116.5 0.1 1.2e-33 115.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CAR24731.1 - 1e-25 89.8 0.6 2.7e-25 88.4 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CAR24731.1 - 2.4e-24 85.3 0.8 6.4e-24 83.9 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CAR24731.1 - 5.3e-19 68.5 2.7 5.3e-19 68.5 2.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 CAR24731.1 - 0.047 14.4 0.1 0.093 13.5 0.1 1.5 1 0 0 1 1 1 0 MRN-interacting protein RNA_pol_Rpb2_45 PF10385.9 CAR24731.1 - 0.23 11.8 1.0 3 8.2 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain Ribosomal_L23 PF00276.20 CAR24732.1 - 1.5e-11 44.5 0.0 3.8e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 ISN1 PF06437.11 CAR24734.1 - 2.1e-171 570.4 0.0 2.4e-171 570.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Choline_transpo PF04515.12 CAR24735.1 - 8.4e-77 258.6 24.0 8.4e-77 258.6 24.0 2.2 2 1 1 3 3 3 1 Plasma-membrane choline transporter Pex14_N PF04695.13 CAR24735.1 - 0.057 14.1 2.0 0.12 13.0 2.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Xpo1 PF08389.12 CAR24736.1 - 1.7e-25 89.9 0.9 1.7e-25 89.9 0.9 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 CAR24736.1 - 1.3e-05 25.0 0.5 6.7e-05 22.7 0.5 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.22 CAR24736.1 - 0.054 13.8 0.2 4.8 7.7 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat LSM PF01423.22 CAR24737.1 - 1.4e-14 53.5 0.0 1.7e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CAR24737.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Hfq protein TRAPPC9-Trs120 PF08626.11 CAR24739.1 - 1.9e-296 986.2 12.2 2.3e-296 985.9 12.2 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Proteasome PF00227.26 CAR24740.1 - 2.3e-45 154.4 0.0 2.9e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CAR24740.1 - 2.4e-15 55.7 0.1 2.4e-15 55.7 0.1 1.8 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Formyl_trans_N PF00551.19 CAR24741.1 - 2.3e-52 177.3 0.0 2.7e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase PINIT PF14324.6 CAR24742.1 - 2e-35 122.3 0.0 3.8e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CAR24742.1 - 1.6e-19 69.4 11.1 2.6e-19 68.7 11.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 CAR24742.1 - 2.5e-08 33.5 0.2 5e-08 32.5 0.2 1.6 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 CAR24742.1 - 0.00027 20.7 2.9 0.00059 19.6 2.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CAR24742.1 - 0.077 13.0 8.3 0.21 11.6 8.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 CAR24742.1 - 7.1 7.1 7.9 13 6.2 7.9 1.5 1 0 0 1 1 1 0 Ring finger domain ICMT PF04140.14 CAR24743.1 - 1.9e-28 98.7 0.7 3.7e-28 97.8 0.7 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CAR24743.1 - 2.3e-13 50.5 2.8 2.3e-13 50.5 2.8 1.8 2 1 1 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.11 CAR24743.1 - 4.4e-05 23.1 1.6 6.4e-05 22.6 1.6 1.2 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 CAR24743.1 - 0.0077 15.8 3.2 0.01 15.4 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HXXEE PF13787.6 CAR24743.1 - 0.13 13.1 0.3 0.13 13.1 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif Romo1 PF10247.9 CAR24743.1 - 0.79 10.1 3.3 0.85 10.0 0.1 2.6 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 zf-HIT PF04438.16 CAR24744.1 - 0.0015 18.3 8.8 0.0026 17.6 8.8 1.4 1 0 0 1 1 1 1 HIT zinc finger NitrOD1 PF18549.1 CAR24744.1 - 0.029 14.3 0.7 0.1 12.6 0.3 2.0 2 0 0 2 2 2 0 Nitrosopumilus output domain 1 Carn_acyltransf PF00755.20 CAR24745.1 - 2e-179 598.0 0.0 2.3e-179 597.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DER1 PF04511.15 CAR24746.1 - 1.9e-37 129.1 11.5 2.6e-37 128.6 11.5 1.1 1 0 0 1 1 1 1 Der1-like family DUF2104 PF09877.9 CAR24746.1 - 0.11 12.8 1.5 0.58 10.4 0.5 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) Nop25 PF09805.9 CAR24747.1 - 3.5e-38 131.2 22.8 3.5e-38 131.2 22.8 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) XhlA PF10779.9 CAR24747.1 - 3.2 8.0 12.2 0.55 10.5 8.1 1.9 2 0 0 2 2 2 0 Haemolysin XhlA EXS PF03124.14 CAR24748.1 - 3e-67 227.3 20.3 3.4e-67 227.1 20.3 1.0 1 0 0 1 1 1 1 EXS family DUF2512 PF10710.9 CAR24748.1 - 0.027 14.1 0.1 2.5 7.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Transp_cyt_pur PF02133.15 CAR24749.1 - 3.5e-159 530.3 36.4 4.1e-159 530.1 36.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MFS_1 PF07690.16 CAR24750.1 - 4.5e-15 55.4 50.9 1.2e-07 31.0 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L2_C PF03947.18 CAR24751.1 - 3.5e-52 175.9 1.6 1.1e-51 174.3 1.7 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CAR24751.1 - 8.5e-28 96.1 0.4 1.3e-26 92.4 0.1 2.3 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain ATP-synt_D PF01813.17 CAR24752.1 - 1.1e-70 237.4 4.7 1.1e-70 237.4 4.7 1.5 1 1 1 2 2 2 1 ATP synthase subunit D RICH PF05062.12 CAR24752.1 - 0.019 15.3 1.9 0.019 15.3 1.9 2.2 2 0 0 2 2 2 0 RICH domain Apt1 PF10351.9 CAR24752.1 - 0.034 13.0 3.8 0.053 12.4 3.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BLOC1_2 PF10046.9 CAR24752.1 - 0.21 11.9 8.3 0.23 11.8 0.0 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.11 CAR24752.1 - 0.25 10.8 4.3 0.6 9.6 2.6 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein CobA_CobO_BtuR PF02572.15 CAR24752.1 - 0.71 10.1 5.5 1.3 9.3 0.2 2.3 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP HET PF06985.11 CAR24752.1 - 5.1 7.5 5.9 11 6.4 3.5 2.5 2 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) TPR_14 PF13428.6 CAR24753.1 - 5.8e-12 45.4 10.5 0.049 14.5 0.0 8.8 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR24753.1 - 8.3e-08 31.8 8.7 0.23 11.7 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR24753.1 - 1.8e-07 31.3 4.0 0.016 15.5 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 CAR24753.1 - 2.1e-07 30.4 5.4 0.0031 16.8 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat Suf PF05843.14 CAR24753.1 - 5.7e-07 29.8 0.2 0.22 11.5 0.0 4.6 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_8 PF13181.6 CAR24753.1 - 2.1e-06 27.5 1.2 2 8.8 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR24753.1 - 1.4e-05 25.5 0.0 37 4.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR24753.1 - 1.8e-05 24.7 0.4 4.5 7.9 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR24753.1 - 4.9e-05 23.0 4.6 0.11 12.4 0.0 5.1 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR24753.1 - 0.00061 20.3 3.2 0.84 10.4 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR24753.1 - 0.00085 19.0 1.0 22 4.8 0.0 4.7 5 0 0 5 5 5 0 TPR repeat TPR_10 PF13374.6 CAR24753.1 - 0.003 17.4 4.2 0.23 11.4 0.0 5.2 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR24753.1 - 0.011 15.1 0.7 1.5 8.1 0.0 3.4 3 1 0 3 3 3 0 MalT-like TPR region Mad3_BUB1_I PF08311.12 CAR24753.1 - 0.056 13.4 19.7 3.5 7.6 0.1 6.7 7 2 1 8 8 8 0 Mad3/BUB1 homology region 1 RPN7 PF10602.9 CAR24753.1 - 0.083 12.6 0.3 1.3 8.7 0.0 2.9 3 0 0 3 3 3 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 CAR24753.1 - 0.27 11.9 1.8 1.6e+02 3.1 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat IMS PF00817.20 CAR24754.1 - 1e-42 145.7 0.0 1.7e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CAR24754.1 - 1e-08 35.9 0.0 3.1e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 CAR24754.1 - 8.3e-06 25.3 0.6 2e-05 24.1 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CAR24754.1 - 0.11 12.8 0.1 0.33 11.3 0.1 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF2608 PF11019.8 CAR24754.1 - 0.12 11.8 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) ACBP PF00887.19 CAR24755.1 - 2.2e-19 69.5 0.0 3.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ribosomal_L11_N PF03946.14 CAR24756.1 - 7.1e-21 73.8 0.2 1.3e-20 73.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CAR24756.1 - 6e-17 61.9 1.6 6.4e-17 61.8 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Mak10 PF04112.13 CAR24757.1 - 3.7e-45 153.5 0.0 6.4e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DASH_Dad4 PF08650.10 CAR24757.1 - 0.11 12.5 0.2 0.33 11.0 0.2 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad4 DUF3019 PF11456.8 CAR24757.1 - 0.11 13.0 0.1 0.32 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3019) AFG1_ATPase PF03969.16 CAR24758.1 - 5.2e-79 265.8 0.1 6e-75 252.4 0.0 2.8 1 1 1 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CAR24758.1 - 1.5e-06 28.7 0.2 2e-05 25.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CAR24758.1 - 0.00041 20.8 0.0 0.00075 19.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR24758.1 - 0.0027 18.0 0.1 0.01 16.1 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CAR24758.1 - 0.0035 17.4 0.1 0.026 14.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAR24758.1 - 0.0055 16.7 0.0 0.022 14.8 0.0 1.9 1 1 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CAR24758.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CAR24758.1 - 0.06 12.8 0.0 0.14 11.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 CAR24758.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CAR24758.1 - 0.12 12.7 0.0 0.6 10.5 0.0 2.1 2 1 1 3 3 3 0 RNA helicase Zn_clus PF00172.18 CAR24760.1 - 1.9e-07 31.1 10.2 3.7e-07 30.2 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR24760.1 - 0.015 14.4 3.0 0.25 10.4 3.0 2.7 1 1 0 1 1 1 0 Fungal specific transcription factor domain Dickkopf_N PF04706.12 CAR24760.1 - 5.3 7.6 7.8 15 6.2 1.3 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region AMPKBI PF04739.15 CAR24762.1 - 2.2e-20 72.7 1.2 3.5e-20 72.1 0.1 2.0 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CAR24762.1 - 1.3e-09 38.2 0.0 2.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PAP1 PF08601.10 CAR24763.1 - 1.2e-19 71.3 0.7 1.2e-19 71.3 0.7 3.8 1 1 2 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 CAR24763.1 - 4.4e-05 23.5 12.7 4.4e-05 23.5 12.7 1.9 2 0 0 2 2 2 1 bZIP transcription factor SHE3 PF17078.5 CAR24763.1 - 0.04 13.6 5.9 0.073 12.8 5.9 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Vpu PF00558.19 CAR24763.1 - 0.071 12.9 3.9 0.16 11.8 3.9 1.6 1 0 0 1 1 1 0 Vpu protein ERM PF00769.19 CAR24763.1 - 0.55 10.0 20.4 1.1 9.0 20.4 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family bZIP_2 PF07716.15 CAR24763.1 - 0.57 10.3 21.5 3.1 7.9 20.9 2.3 1 1 1 2 2 2 0 Basic region leucine zipper PDE4_UCR PF18100.1 CAR24763.1 - 3.2 8.4 6.9 0.33 11.6 1.6 2.1 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) RBR PF17208.3 CAR24763.1 - 6.4 7.6 8.7 0.65 10.8 2.4 2.6 2 1 0 2 2 2 0 RNA binding Region Sterol_MT_C PF08498.10 CAR24764.1 - 1.6e-26 92.3 2.1 2.6e-26 91.7 2.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CAR24764.1 - 5.8e-19 68.5 0.0 1.1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR24764.1 - 3.2e-17 63.0 0.0 6.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR24764.1 - 3.2e-16 59.5 0.0 4.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAR24764.1 - 3.1e-14 52.9 0.1 4.2e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CAR24764.1 - 8.1e-12 45.8 0.1 2.3e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR24764.1 - 2.5e-11 43.7 0.0 3.7e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR24764.1 - 2.9e-08 33.3 0.0 4.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CAR24764.1 - 4.8e-06 26.3 0.1 9.6e-06 25.3 0.1 1.4 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 CAR24764.1 - 0.0028 17.1 0.1 0.0065 15.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CAR24764.1 - 0.0059 16.4 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 CAR24764.1 - 0.008 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 CAR24764.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CAR24764.1 - 0.098 12.6 0.1 0.21 11.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.24 CAR24765.1 - 1e-26 93.8 35.5 4.1e-17 62.2 11.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAR24765.1 - 5e-18 65.1 43.8 5.9e-09 35.3 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 CAR24766.1 - 1e-105 353.4 0.7 1e-105 353.4 0.7 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAR24766.1 - 5.3e-26 91.3 0.2 1.3e-25 90.1 0.2 1.7 1 0 0 1 1 1 1 Microtubule binding PDCD7 PF16021.5 CAR24766.1 - 0.021 14.0 1.1 0.044 12.9 1.1 1.4 1 0 0 1 1 1 0 Programmed cell death protein 7 AAA_16 PF13191.6 CAR24766.1 - 0.035 14.5 0.9 4.9 7.5 0.0 3.5 2 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CAR24766.1 - 0.67 10.2 3.1 0.71 10.1 0.2 2.6 2 2 0 2 2 2 0 AAA domain Dynein_light PF01221.18 CAR24767.1 - 4.2e-30 103.9 0.0 4.6e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PX PF00787.24 CAR24768.1 - 7.2e-14 51.7 0.1 2.3e-13 50.1 0.1 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CAR24768.1 - 4.1e-06 26.5 7.2 4.1e-06 26.5 7.2 2.1 2 0 0 2 2 2 1 Vps5 C terminal like Helitron_like_N PF14214.6 CAR24768.1 - 0.017 15.4 0.9 0.042 14.1 0.9 1.6 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DUF4298 PF14131.6 CAR24768.1 - 4.1 7.4 7.8 5.3 7.1 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) BORCS7 PF16088.5 CAR24768.1 - 5.3 7.4 9.3 17 5.7 1.7 3.4 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 FliD_N PF02465.18 CAR24768.1 - 6 7.6 9.1 0.74 10.6 1.4 2.8 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus RecG_N PF17190.4 CAR24768.1 - 6.4 7.6 9.9 2.7 8.8 0.2 3.9 3 1 1 4 4 4 0 RecG N-terminal helical domain Rpn9_C PF18261.1 CAR24769.1 - 8.2e-19 66.9 2.6 1.9e-18 65.8 2.6 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix PCI PF01399.27 CAR24769.1 - 1.9e-12 47.6 0.0 6e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 PCI domain Glyco_transf_7N PF13733.6 CAR24769.1 - 0.0082 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 ELF PF03317.13 CAR24769.1 - 0.012 15.6 0.2 0.028 14.4 0.2 1.6 1 0 0 1 1 1 0 ELF protein HU-CCDC81_euk_2 PF18289.1 CAR24769.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 2 Abhydrolase_3 PF07859.13 CAR24770.1 - 2.8e-09 37.2 0.0 3.1e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CAR24770.1 - 0.0027 17.4 0.1 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Rad60-SLD PF11976.8 CAR24770.1 - 0.0036 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Abhydrolase_6 PF12697.7 CAR24770.1 - 0.0038 17.9 0.0 0.0039 17.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 CAR24770.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase LIDHydrolase PF10230.9 CAR24770.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 CAR24770.1 - 0.018 14.5 0.1 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CAR24770.1 - 0.054 12.8 0.0 0.2 10.9 0.0 1.8 1 1 0 2 2 2 0 Serine aminopeptidase, S33 DUF900 PF05990.12 CAR24770.1 - 0.071 12.6 0.1 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) eIF3g PF12353.8 CAR24771.1 - 3.3e-43 147.0 1.6 5.2e-43 146.4 1.6 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CAR24771.1 - 2.4e-12 46.5 0.0 5.3e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 CAR24771.1 - 0.35 11.2 1.3 1.4 9.3 0.2 2.2 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Ribosomal_L33 PF00471.20 CAR24772.1 - 0.00086 19.7 0.1 0.0014 19.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L33 Spt5_N PF11942.8 CAR24773.1 - 9.2e-22 77.9 11.4 9.2e-22 77.9 11.4 4.1 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 CAR24773.1 - 3.2e-21 75.0 0.0 6.7e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CAR24773.1 - 2e-14 52.9 12.3 0.0018 18.2 0.2 4.6 4 0 0 4 4 4 4 KOW motif CTD PF12815.7 CAR24773.1 - 0.00014 22.3 24.1 0.00014 22.3 24.1 3.5 3 1 0 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 DUF3912 PF13051.6 CAR24773.1 - 0.0058 16.9 1.6 0.38 11.1 0.1 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) Leucyl-specific PF14795.6 CAR24773.1 - 0.054 13.6 0.3 3.4 7.8 0.0 3.0 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF4438 PF14505.6 CAR24773.1 - 0.11 11.5 3.4 0.18 10.7 0.0 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4438) Nucleo_P87 PF07267.11 CAR24773.1 - 1.6 7.5 22.8 3.2 6.5 22.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 EmrE PF13536.6 CAR24774.1 - 0.2 11.2 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter Rad33 PF08730.10 CAR24775.1 - 2.2e-14 53.8 2.0 7.6e-08 32.5 0.2 2.1 1 1 1 2 2 2 2 Rad33 EMP24_GP25L PF01105.24 CAR24776.1 - 4.8e-41 140.7 0.0 5.7e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Takusan PF04822.13 CAR24776.1 - 0.17 11.8 0.6 0.28 11.1 0.6 1.4 1 0 0 1 1 1 0 Takusan M16C_assoc PF08367.11 CAR24777.1 - 5.2e-70 235.4 0.0 8.9e-70 234.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CAR24777.1 - 5.7e-27 94.9 0.5 9.7e-19 68.1 0.1 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR24777.1 - 5e-07 29.8 0.0 1.8e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RRM_1 PF00076.22 CAR24778.1 - 1.7e-28 98.2 0.5 1e-16 60.5 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR24778.1 - 0.00029 20.6 0.0 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CAR24778.1 - 0.0033 17.0 0.0 0.0092 15.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBX PF00789.20 CAR24779.1 - 8.4e-14 51.5 0.4 1.2e-10 41.5 0.1 3.5 2 1 0 2 2 2 2 UBX domain UBA_4 PF14555.6 CAR24779.1 - 2.9e-09 36.6 0.0 6.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain BET PF17035.5 CAR24779.1 - 0.062 13.5 2.0 5.9 7.1 0.6 2.9 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation MAS20 PF02064.15 CAR24779.1 - 0.16 12.0 5.4 14 5.8 4.8 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor LamB_YcsF PF03746.16 CAR24779.1 - 0.3 10.7 2.4 0.49 10.0 2.4 1.3 1 0 0 1 1 1 0 LamB/YcsF family Methyltransf_11 PF08241.12 CAR24780.1 - 3.3e-12 46.9 0.0 7.1e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR24780.1 - 6.8e-10 39.5 0.3 1.6e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR24780.1 - 1.7e-06 27.9 0.0 2.9e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR24780.1 - 4.9e-05 23.2 0.1 0.00011 22.1 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR24780.1 - 6.4e-05 23.6 0.7 0.00018 22.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PIG-S PF10510.9 CAR24781.1 - 3e-126 422.3 2.7 4e-126 421.8 2.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.14 CAR24782.1 - 5.7e-27 93.6 0.5 5.6e-23 80.8 0.6 2.8 2 0 0 2 2 2 2 hTAFII28-like protein conserved region LCM PF04072.14 CAR24783.1 - 1.7e-21 77.0 0.0 2.2e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Metallophos PF00149.28 CAR24784.1 - 2e-36 126.4 0.1 3.6e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR24784.1 - 2e-18 66.5 0.3 4e-18 65.6 0.3 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PIG-P PF08510.12 CAR24785.1 - 6.3e-36 122.9 1.8 7.4e-36 122.7 1.8 1.1 1 0 0 1 1 1 1 PIG-P DHHC PF01529.20 CAR24785.1 - 0.017 15.2 0.8 0.025 14.7 0.8 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3341 PF11821.8 CAR24785.1 - 0.034 13.8 0.7 0.043 13.5 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) TMEMspv1-c74-12 PF11044.8 CAR24785.1 - 5.2 7.1 5.2 2.5 8.2 0.3 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein EamA PF00892.20 CAR24787.1 - 8.7e-13 48.6 38.3 3.3e-08 33.8 3.9 3.6 3 1 1 4 4 4 2 EamA-like transporter family DUF3955 PF13127.6 CAR24787.1 - 3.4e-07 30.0 2.9 3.4e-07 30.0 2.9 4.4 5 1 0 5 5 5 2 Protein of unknown function (DUF3955) OST3_OST6 PF04756.13 CAR24788.1 - 9.3e-68 228.7 2.7 1.1e-67 228.5 2.7 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CAR24788.1 - 0.0036 17.3 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin LRS4 PF10422.9 CAR24789.1 - 5.4e-20 72.0 30.8 2.1e-15 57.0 13.9 3.5 1 1 1 2 2 2 2 Monopolin complex subunit LRS4 TSC22 PF01166.18 CAR24789.1 - 0.098 13.0 3.3 0.24 11.7 3.3 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF3573 PF12097.8 CAR24789.1 - 0.14 11.0 1.9 0.12 11.2 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) FUSC PF04632.12 CAR24789.1 - 0.19 10.2 0.1 0.21 10.1 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3391 PF11871.8 CAR24789.1 - 1.5 9.4 8.1 1.2 9.7 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) CENP-H PF05837.12 CAR24789.1 - 7.1 7.1 11.1 0.81 10.1 4.1 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) UDG PF03167.19 CAR24791.1 - 5.4e-21 75.2 0.0 9.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DOT1 PF08123.13 CAR24792.1 - 1.7e-85 285.7 0.0 2.6e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pribosyltran PF00156.27 CAR24793.1 - 7.3e-15 54.8 0.0 9.6e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAR24793.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Nse5 PF08691.10 CAR24794.1 - 1.9e-151 505.3 0.7 2.2e-151 505.0 0.7 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Med13_N PF11597.8 CAR24795.1 - 1e-66 225.5 4.0 1e-66 225.5 4.0 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 CAR24795.1 - 2.8e-24 86.0 5.1 2.9e-18 66.2 0.1 3.0 2 1 0 3 3 3 2 Mediator complex subunit 13 C-terminal domain DUF676 PF05057.14 CAR24796.1 - 8.4e-44 149.7 0.0 1.3e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 CAR24796.1 - 0.0059 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 CAR24796.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FAD-oxidase_C PF02913.19 CAR24797.1 - 1.9e-47 162.0 0.0 3.1e-47 161.3 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAR24797.1 - 8.7e-37 126.0 0.1 1.6e-36 125.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain ECM11 PF15463.6 CAR24798.1 - 6.7e-22 78.5 0.0 6.7e-22 78.5 0.0 2.5 1 1 1 2 2 2 1 Extracellular mutant protein 11 Lin-8 PF03353.15 CAR24798.1 - 4.6 6.7 8.1 5.7 6.4 7.8 1.4 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 CAR24798.1 - 9.9 4.7 8.8 11 4.6 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_S17e PF00833.18 CAR24799.1 - 3.6e-56 188.3 0.6 3.6e-56 188.3 0.6 1.3 1 1 1 2 2 2 1 Ribosomal S17 PemK_toxin PF02452.17 CAR24799.1 - 0.081 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system ZZ PF00569.17 CAR24800.1 - 8e-16 57.6 8.2 1.4e-15 56.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CAR24800.1 - 5.7e-09 36.0 0.1 1.3e-08 34.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 CAR24800.1 - 2.7e-07 30.8 0.0 4e-06 27.1 0.0 2.6 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 CAR24800.1 - 0.00023 21.4 0.0 0.00055 20.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tnp_zf-ribbon_2 PF13842.6 CAR24800.1 - 7.8 7.4 9.7 23 5.9 9.7 1.9 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon U3_assoc_6 PF08640.11 CAR24801.1 - 2.2e-31 107.7 5.5 2.8e-29 101.0 2.6 2.7 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CAR24801.1 - 0.00012 21.3 4.3 0.054 12.6 1.0 2.6 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.14 CAR24801.1 - 0.00013 22.1 5.7 0.0017 18.4 0.3 3.7 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CAR24801.1 - 0.003 18.2 0.0 1.7 9.6 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR24801.1 - 0.024 14.3 0.1 2.3 8.0 0.0 3.2 4 0 0 4 4 4 0 TPR repeat TPR_17 PF13431.6 CAR24801.1 - 0.049 14.0 0.1 27 5.4 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L4 PF00573.22 CAR24802.1 - 3.3e-47 160.7 0.0 3.9e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.22 CAR24803.1 - 8.9e-57 191.0 2.8 1e-56 190.8 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CAR24803.1 - 0.0014 17.4 0.1 0.0018 17.1 0.1 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Homeodomain PF00046.29 CAR24804.1 - 5.7e-17 61.3 4.1 1.3e-16 60.2 4.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CAR24804.1 - 0.00022 21.0 0.3 0.0018 18.2 0.1 2.5 2 0 0 2 2 2 1 Homeobox KN domain Metallophos PF00149.28 CAR24805.1 - 6.4e-07 30.1 1.7 7.6e-07 29.8 0.4 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase FeoA PF04023.14 CAR24805.1 - 0.023 15.0 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 FeoA domain Lipase_GDSL PF00657.22 CAR24805.1 - 0.084 12.8 0.0 0.33 10.9 0.0 1.9 3 0 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase AP3D1 PF06375.11 CAR24805.1 - 0.085 13.1 6.0 0.18 12.0 6.0 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF2070 PF09843.9 CAR24805.1 - 0.18 10.1 0.1 0.34 9.1 0.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) AhpC-TSA PF00578.21 CAR24806.1 - 5.1e-33 113.6 0.0 1.2e-32 112.5 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CAR24806.1 - 1.2e-17 64.0 0.0 2.3e-17 63.1 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CAR24806.1 - 1.3e-10 40.9 0.2 2.5e-10 40.0 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CAR24806.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC Rad60-SLD_2 PF13881.6 CAR24807.1 - 0.001 19.2 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CAR24807.1 - 0.018 14.8 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin family HIG_1_N PF04588.13 CAR24808.1 - 1.8e-17 63.3 1.3 2.5e-17 62.8 1.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2514 PF10721.9 CAR24808.1 - 0.48 10.5 9.5 0.23 11.5 6.7 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2514) OmpH PF03938.14 CAR24808.1 - 1 9.7 11.4 1.9 8.9 11.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Guanylate_kin PF00625.21 CAR24809.1 - 1.1e-67 227.3 0.0 1.2e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CAR24809.1 - 8.3e-07 29.5 0.0 1.3e-06 28.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CAR24809.1 - 2.2e-05 25.0 0.0 3.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR24809.1 - 2.2e-05 24.7 0.0 9.3e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAR24809.1 - 4.3e-05 23.6 0.3 0.00043 20.3 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CAR24809.1 - 5.5e-05 23.4 0.0 0.00041 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CAR24809.1 - 0.00046 20.6 0.2 0.0045 17.4 0.2 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CAR24809.1 - 0.00061 20.2 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CAR24809.1 - 0.00072 19.3 0.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CAR24809.1 - 0.0013 19.0 0.1 0.0029 17.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 CAR24809.1 - 0.0019 18.1 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 CAR24809.1 - 0.0026 18.3 0.1 0.0034 17.9 0.1 1.4 1 1 0 1 1 1 1 ABC transporter T2SSE PF00437.20 CAR24809.1 - 0.0026 16.8 0.1 0.0086 15.2 0.1 1.9 1 1 1 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 CAR24809.1 - 0.0034 16.9 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 CAR24809.1 - 0.0037 17.3 0.0 0.0078 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CAR24809.1 - 0.0063 16.4 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Rad17 PF03215.15 CAR24809.1 - 0.0068 16.3 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain NTPase_1 PF03266.15 CAR24809.1 - 0.0068 16.3 0.1 0.016 15.2 0.1 1.6 1 1 0 1 1 1 1 NTPase DUF2075 PF09848.9 CAR24809.1 - 0.0083 15.4 0.0 0.025 13.9 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.6 CAR24809.1 - 0.0083 15.8 1.5 0.024 14.4 0.3 2.2 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAR24809.1 - 0.0089 15.8 0.0 0.028 14.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CAR24809.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CAR24809.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CAR24809.1 - 0.036 13.3 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 CAR24809.1 - 0.057 13.0 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 CAR24809.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase MobB PF03205.14 CAR24809.1 - 0.083 12.8 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.15 CAR24809.1 - 0.084 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Pox_A32 PF04665.12 CAR24809.1 - 0.098 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_17 PF13207.6 CAR24809.1 - 0.099 13.1 0.1 0.91 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CAR24809.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.6 CAR24809.1 - 0.12 12.7 0.1 0.8 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CAR24809.1 - 0.15 12.1 0.1 1.1 9.3 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CAR24809.1 - 0.16 11.9 0.1 0.36 10.8 0.1 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CAR24809.1 - 0.18 12.3 0.8 0.28 11.6 0.4 1.5 1 1 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.21 CAR24810.1 - 5e-68 229.6 38.4 6.4e-68 229.3 38.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.6 CAR24810.1 - 0.21 11.5 4.5 0.24 11.3 1.7 2.3 2 0 0 2 2 2 0 Myc target protein 1 Ndc1_Nup PF09531.10 CAR24811.1 - 1.6e-106 357.5 6.8 7.7e-106 355.2 6.8 1.8 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.15 CAR24812.1 - 5.4e-55 185.5 0.0 7.6e-55 185.0 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein HECT PF00632.25 CAR24813.1 - 5e-91 305.4 1.0 1.1e-90 304.2 0.1 2.2 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CAR24813.1 - 3.8e-55 187.8 10.4 4.7e-54 184.2 3.2 3.4 3 1 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CAR24813.1 - 1.5e-51 175.5 0.7 1.7e-50 172.1 0.0 3.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) UBM PF14377.6 CAR24813.1 - 7.3e-18 63.4 9.9 3.2e-10 39.1 0.7 2.6 2 0 0 2 2 2 2 Ubiquitin binding region T4_Gp59_C PF08994.10 CAR24813.1 - 0.025 15.2 1.8 0.13 12.8 1.8 2.3 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Ribonuc_2-5A PF06479.12 CAR24814.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.5 2 0 0 2 2 2 0 Ribonuclease 2-5A MSC PF09402.10 CAR24815.1 - 2.3e-98 329.8 2.4 2.3e-98 329.8 2.4 2.0 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CAR24815.1 - 6.4e-16 57.8 0.2 6.4e-16 57.8 0.2 2.2 2 0 0 2 2 2 1 HeH/LEM domain DUF356 PF04009.12 CAR24815.1 - 0.11 12.8 0.2 0.27 11.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF356) A_deaminase PF00962.22 CAR24816.1 - 8.6e-129 429.6 0.0 1.6e-128 428.7 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase DHHC PF01529.20 CAR24817.1 - 5.8e-29 100.9 5.2 5.8e-29 100.9 5.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase MAT1 PF06391.13 CAR24818.1 - 4.7e-66 222.5 23.3 6.2e-66 222.1 23.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CAR24818.1 - 1e-28 99.0 7.7 1.8e-28 98.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR24818.1 - 0.00023 20.9 4.7 0.00055 19.7 4.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR24818.1 - 0.00031 21.0 6.1 0.00055 20.2 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CAR24818.1 - 0.00082 19.2 5.2 0.0015 18.3 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FliS PF02561.14 CAR24818.1 - 0.0034 17.6 1.3 0.0034 17.6 1.3 2.3 1 1 1 2 2 2 1 Flagellar protein FliS UPF0160 PF03690.13 CAR24818.1 - 0.0039 16.9 3.0 0.0049 16.5 3.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) zf-C3HC4 PF00097.25 CAR24818.1 - 0.0073 16.2 5.3 0.028 14.3 5.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR24818.1 - 0.028 14.4 6.3 0.064 13.3 6.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CAR24818.1 - 0.048 13.3 1.2 0.092 12.4 1.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CAR24818.1 - 0.093 12.7 9.3 1.4 9.0 9.3 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Spectrin PF00435.21 CAR24818.1 - 0.095 13.2 9.2 0.038 14.5 5.4 2.1 1 1 1 2 2 2 0 Spectrin repeat Prok-RING_4 PF14447.6 CAR24818.1 - 1.1 9.2 8.7 4.8 7.1 3.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CAR24818.1 - 1.1 9.1 9.8 13 5.6 10.0 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF3797 PF12677.7 CAR24818.1 - 1.9 8.4 6.2 0.83 9.6 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) CGI-121 PF08617.10 CAR24819.1 - 5.9e-35 120.8 0.0 7.1e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Crystall PF00030.19 CAR24819.1 - 0.041 14.1 0.0 0.092 13.0 0.0 1.5 2 0 0 2 2 2 0 Beta/Gamma crystallin MRP-L28 PF09812.9 CAR24821.1 - 5.5e-36 124.1 3.8 6.7e-36 123.8 3.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 FYRC PF05965.14 CAR24821.1 - 0.0027 17.8 0.1 0.08 13.1 0.1 2.4 2 0 0 2 2 2 1 F/Y rich C-terminus TPT PF03151.16 CAR24822.1 - 3e-19 69.5 10.7 8.3e-19 68.0 10.7 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CAR24822.1 - 3.9e-07 29.6 12.7 1.2e-06 28.0 12.6 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CAR24822.1 - 4.8e-07 30.0 25.5 0.00034 20.8 5.2 3.6 2 2 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CAR24822.1 - 6e-05 22.4 0.4 6e-05 22.4 0.4 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport Nuc_sug_transp PF04142.15 CAR24822.1 - 0.0024 17.1 4.0 0.0083 15.3 1.0 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter TMEM234 PF10639.9 CAR24822.1 - 0.083 12.9 12.3 0.72 9.9 0.9 2.9 3 0 0 3 3 3 0 Putative transmembrane family 234 zf-C2H2_4 PF13894.6 CAR24823.1 - 0.0032 18.2 13.4 0.14 13.1 1.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR24823.1 - 0.0047 17.3 16.0 0.0059 17.0 3.4 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR24823.1 - 0.0064 16.9 0.5 0.0064 16.9 0.5 3.5 3 1 0 3 3 3 1 Zinc-finger double domain PriA_CRR PF18319.1 CAR24823.1 - 0.17 11.9 4.7 0.2 11.7 0.6 2.7 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain zf-AN1 PF01428.16 CAR24823.1 - 0.69 10.1 6.7 2.9 8.1 2.1 2.6 2 0 0 2 2 2 0 AN1-like Zinc finger PyrI_C PF02748.15 CAR24823.1 - 0.91 9.5 6.3 1.6 8.7 1.3 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 CAR24823.1 - 1.1 9.9 5.2 0.89 10.2 0.1 3.0 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF3020 PF11223.8 CAR24824.1 - 1.4e-18 67.1 10.8 1.4e-18 67.1 10.8 7.4 6 0 0 6 6 6 1 Protein of unknown function (DUF3020) p450 PF00067.22 CAR24825.1 - 4.3e-102 342.2 0.0 5.1e-102 342.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.12 CAR24826.1 - 0.013 16.1 0.0 0.072 13.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 CAR24826.1 - 0.018 15.7 0.0 0.051 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Sod_Fe_C PF02777.18 CAR24827.1 - 5.4e-33 113.2 0.4 9.5e-33 112.4 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CAR24827.1 - 1.4e-25 89.5 0.2 2.6e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pkinase PF00069.25 CAR24828.1 - 1.3e-60 205.0 0.0 1.7e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24828.1 - 3.4e-29 101.9 0.0 4.8e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR24828.1 - 1.4e-09 37.7 0.0 2.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR24828.1 - 0.00036 20.5 0.0 0.0052 16.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR24828.1 - 0.00044 19.7 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CAR24828.1 - 0.0056 16.3 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CAR24828.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CAR24828.1 - 0.095 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CAR24828.1 - 0.17 10.6 0.1 0.37 9.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DAO PF01266.24 CAR24829.1 - 1.4e-81 274.8 0.0 1.7e-81 274.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR24829.1 - 1.2e-06 28.6 0.0 4.3e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CAR24829.1 - 1.6e-05 24.3 0.0 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAR24829.1 - 0.0011 18.2 0.1 0.0019 17.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 CAR24829.1 - 0.0036 16.2 0.0 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 CAR24829.1 - 0.011 15.7 0.1 0.048 13.6 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CAR24829.1 - 0.025 14.8 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 CAR24829.1 - 0.058 14.0 0.1 0.14 12.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2201_N PF13203.6 CAR24829.1 - 0.15 11.6 1.8 0.22 11.1 1.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain SNARE PF05739.19 CAR24830.1 - 0.00076 19.4 0.1 0.00076 19.4 0.1 2.8 4 0 0 4 4 2 1 SNARE domain MPS2 PF17060.5 CAR24830.1 - 0.0011 18.3 5.6 0.0016 17.8 2.1 2.0 1 1 1 2 2 2 1 Monopolar spindle protein 2 Sulfatase PF00884.23 CAR24830.1 - 0.0035 16.8 0.6 1.5 8.2 0.1 2.2 2 0 0 2 2 2 2 Sulfatase Sipho_Gp157 PF05565.11 CAR24830.1 - 0.017 15.1 7.0 0.028 14.4 1.1 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 TMPIT PF07851.13 CAR24830.1 - 0.044 13.0 1.7 0.095 11.9 1.0 1.8 1 1 1 2 2 2 0 TMPIT-like protein FlaC_arch PF05377.11 CAR24830.1 - 0.045 14.1 6.8 3.3 8.2 0.2 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) RBD-FIP PF09457.10 CAR24830.1 - 0.064 13.2 4.0 7.8 6.5 0.1 3.5 3 0 0 3 3 3 0 FIP domain RmuC PF02646.16 CAR24830.1 - 0.07 12.3 5.3 0.084 12.0 0.6 2.3 2 1 1 3 3 3 0 RmuC family Sec20 PF03908.13 CAR24830.1 - 0.071 13.0 1.4 0.12 12.3 0.2 1.9 2 1 0 2 2 2 0 Sec20 Ran-binding PF05508.11 CAR24830.1 - 0.097 11.6 1.7 0.13 11.2 1.7 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF4848 PF16140.5 CAR24830.1 - 0.12 11.9 2.2 0.42 10.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4848) DUF745 PF05335.13 CAR24830.1 - 0.13 12.0 6.1 0.89 9.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) WXG100 PF06013.12 CAR24830.1 - 0.15 12.3 5.8 3.8 7.8 0.1 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG HisKA_3 PF07730.13 CAR24830.1 - 0.15 12.6 6.4 3.2 8.4 0.2 2.6 3 0 0 3 3 2 0 Histidine kinase Baculo_PEP_C PF04513.12 CAR24830.1 - 0.29 11.2 3.3 1 9.4 0.5 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CAR24830.1 - 0.31 11.5 3.2 2.4 8.7 0.3 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 CAR24830.1 - 0.35 11.6 5.7 0.76 10.5 0.5 2.5 2 1 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 CAR24830.1 - 0.4 10.7 8.6 1.1 9.4 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 CAR24830.1 - 0.5 11.0 8.8 16 6.1 8.8 2.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal YPEB PF14620.6 CAR24830.1 - 0.73 9.1 7.4 1.4 8.1 0.3 2.1 2 0 0 2 2 2 0 YpeB sporulation Noelin-1 PF12308.8 CAR24830.1 - 0.76 9.8 5.8 2.3 8.2 0.9 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein Uds1 PF15456.6 CAR24830.1 - 0.87 9.8 7.9 1 9.6 5.4 2.2 2 1 1 3 3 3 0 Up-regulated During Septation SlyX PF04102.12 CAR24830.1 - 1.2 9.8 0.1 1.2 9.8 0.1 4.0 3 2 1 4 4 4 0 SlyX FapA PF03961.13 CAR24830.1 - 1.4 7.5 3.6 4.3 5.8 1.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A ATG16 PF08614.11 CAR24830.1 - 1.4 9.1 15.9 4.7 7.4 4.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 CAR24830.1 - 2.8 7.9 6.2 6.1 6.9 0.7 2.5 2 1 0 2 2 2 0 Laminin Domain II BST2 PF16716.5 CAR24830.1 - 3.1 8.4 10.6 11 6.7 1.8 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Csm1_N PF18504.1 CAR24830.1 - 3.3 8.1 9.4 17 5.8 0.1 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain Cnn_1N PF07989.11 CAR24830.1 - 3.8 7.8 9.3 20 5.5 1.7 3.3 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 YabA PF06156.13 CAR24830.1 - 4.5 8.0 8.9 12 6.6 0.8 2.6 1 1 1 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 CAR24830.1 - 5 7.5 10.8 0.88 9.9 0.3 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 CAR24830.1 - 7 6.1 9.7 21 4.5 9.7 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Dpy-30 PF05186.13 CAR24831.1 - 4.1e-18 64.8 0.1 5.3e-18 64.4 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif DUF4026 PF13218.6 CAR24831.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) Mito_carr PF00153.27 CAR24832.1 - 6.2e-10 38.9 0.0 0.00063 19.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Rnk_N PF14760.6 CAR24833.1 - 0.051 14.1 6.8 1.5 9.3 6.8 3.0 1 1 0 1 1 1 0 Rnk N-terminus DUF755 PF05501.11 CAR24833.1 - 0.081 13.2 2.1 0.15 12.3 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF5490 PF17593.2 CAR24833.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5490) BLOC1_2 PF10046.9 CAR24833.1 - 2 8.8 7.8 1.1 9.7 2.3 2.7 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YscO PF07321.12 CAR24833.1 - 4.7 7.2 21.6 2.7 8.0 7.3 2.8 1 1 2 3 3 3 0 Type III secretion protein YscO TMF_TATA_bd PF12325.8 CAR24833.1 - 7.1 6.9 16.0 15 5.9 4.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 CAR24833.1 - 7.5 4.9 11.1 10 4.5 11.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DHR10 PF18595.1 CAR24833.1 - 7.8 6.6 20.2 2 8.5 10.6 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Ribosomal_L27e PF01777.18 CAR24834.1 - 1.4e-36 124.7 5.1 2e-36 124.2 5.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CAR24834.1 - 0.00066 19.5 2.2 0.0013 18.6 2.2 1.5 1 0 0 1 1 1 1 KOW motif tRNA-synt_2b PF00587.25 CAR24835.1 - 2.8e-24 86.0 0.0 4.6e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CAR24835.1 - 1.9e-05 24.8 5.4 3.3e-05 24.1 5.4 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 CAR24835.1 - 0.00023 21.0 6.3 0.00042 20.2 6.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF3584 PF12128.8 CAR24835.1 - 0.0036 14.9 3.8 0.0047 14.5 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Atg14 PF10186.9 CAR24835.1 - 0.012 14.7 1.5 0.017 14.3 1.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4686 PF15742.5 CAR24835.1 - 0.017 14.2 9.6 0.026 13.7 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Spc7 PF08317.11 CAR24835.1 - 0.11 11.4 6.7 0.17 10.7 6.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_5 PF12688.7 CAR24835.1 - 0.11 12.7 0.8 0.2 11.9 0.8 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat FapA PF03961.13 CAR24835.1 - 0.12 10.9 1.8 0.17 10.5 1.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PEARLI-4 PF05278.12 CAR24835.1 - 0.14 11.7 5.9 0.23 11.0 5.9 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) TMPIT PF07851.13 CAR24835.1 - 0.31 10.3 2.9 0.46 9.7 2.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein FUSC PF04632.12 CAR24835.1 - 0.37 9.3 1.4 0.49 8.9 1.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-RING_9 PF13901.6 CAR24835.1 - 0.4 10.6 1.6 0.69 9.9 1.6 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon YPEB PF14620.6 CAR24835.1 - 0.41 9.9 3.6 0.68 9.2 3.6 1.2 1 0 0 1 1 1 0 YpeB sporulation Cep57_CLD_2 PF14197.6 CAR24835.1 - 0.54 10.4 10.9 1.1 9.4 10.9 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 5_nucleotid PF05761.14 CAR24835.1 - 0.82 8.5 4.2 1.3 7.8 4.2 1.2 1 0 0 1 1 1 0 5' nucleotidase family UPF0242 PF06785.11 CAR24835.1 - 1.5 8.8 8.5 2.8 8.0 8.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Metallophos_2 PF12850.7 CAR24836.1 - 1.5e-08 35.0 0.0 2.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Acetyltransf_1 PF00583.25 CAR24837.1 - 3.9e-12 46.4 0.0 5.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR24837.1 - 1.2e-07 31.7 0.1 1.6e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR24837.1 - 2.2e-05 24.3 0.1 3.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CAR24837.1 - 2.8e-05 24.5 0.0 4.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR24837.1 - 0.0048 17.0 0.1 0.0081 16.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CAR24837.1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase TRAPP PF04051.16 CAR24838.1 - 1.3e-44 151.5 0.0 1.7e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component YqfQ PF14181.6 CAR24838.1 - 0.019 15.2 2.0 0.019 15.2 2.0 1.5 1 1 0 1 1 1 0 YqfQ-like protein PSRT PF07636.11 CAR24839.1 - 0.0016 18.1 2.8 0.0016 18.1 2.8 2.3 2 0 0 2 2 2 1 PSRT DDHD PF02862.17 CAR24840.1 - 5.6e-39 134.6 3.1 2.3e-25 90.1 0.1 2.9 2 1 1 3 3 3 2 DDHD domain LCAT PF02450.15 CAR24840.1 - 2e-06 27.3 0.0 0.00046 19.5 0.0 2.2 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 CAR24840.1 - 0.002 17.7 0.1 1.1 8.7 0.0 2.6 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CAR24840.1 - 0.0093 15.8 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 1 Palmitoyl protein thioesterase RNA_Me_trans PF04252.13 CAR24841.1 - 1.3e-78 263.1 0.0 1.5e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase ATP19 PF11022.8 CAR24842.1 - 2.8e-12 46.8 0.2 3.7e-12 46.4 0.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit K Myelin_PLP PF01275.19 CAR24842.1 - 0.17 11.7 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Cpn10 PF00166.21 CAR24843.1 - 1e-27 96.0 0.0 1.1e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.10 CAR24844.1 - 4.3e-56 190.2 14.7 6.3e-56 189.6 14.7 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CAR24844.1 - 4.5e-31 107.9 0.0 4.5e-31 107.9 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) DUF4306 PF14154.6 CAR24844.1 - 0.019 15.1 1.4 2.1 8.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) Flo11 PF10182.9 CAR24844.1 - 0.023 14.8 0.5 0.071 13.3 0.0 1.9 2 0 0 2 2 2 0 Flo11 domain DUF2797 PF10977.8 CAR24844.1 - 5 7.0 7.8 0.74 9.7 2.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2797) Usp PF00582.26 CAR24845.1 - 0.15 12.6 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Universal stress protein family Arf PF00025.21 CAR24846.1 - 7.5e-29 100.4 0.4 1.1e-27 96.7 0.2 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 CAR24846.1 - 6.1e-17 61.7 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24846.1 - 1.2e-14 54.5 0.0 2.8e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CAR24846.1 - 1.8e-09 37.7 0.0 4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAR24846.1 - 2e-07 30.6 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR24846.1 - 1.8e-06 27.7 0.0 0.00046 19.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAR24846.1 - 2.9e-06 26.8 0.0 4.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CAR24846.1 - 4.9e-06 25.9 1.7 8.1e-05 21.9 0.0 2.6 1 1 2 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.23 CAR24846.1 - 0.0033 17.5 0.1 0.26 11.3 0.1 2.3 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 CAR24846.1 - 0.057 13.4 0.1 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 CAR24846.1 - 0.077 12.8 0.1 0.32 10.7 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein P22_Cro PF14549.6 CAR24846.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro RsgA_GTPase PF03193.16 CAR24846.1 - 0.17 11.8 0.1 2 8.3 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase DUF2470 PF10615.9 CAR24847.1 - 3.1e-16 59.8 0.0 1.2e-15 57.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2470) QCR10 PF09796.9 CAR24847.1 - 0.12 12.4 1.2 0.25 11.4 0.2 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pkinase PF00069.25 CAR24848.1 - 1.2e-75 254.3 0.1 1.8e-75 253.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 CAR24848.1 - 4.2e-58 194.9 0.1 1.5e-57 193.1 0.1 2.0 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 CAR24848.1 - 3.8e-37 128.0 0.0 5.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 CAR24848.1 - 7.5e-21 74.0 3.6 9.3e-21 73.7 1.7 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CAR24848.1 - 1.2e-09 37.9 0.0 2.7e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CAR24848.1 - 9.4e-05 22.1 0.8 0.0002 21.0 0.6 1.6 2 0 0 2 2 2 1 RIO1 family YukC PF10140.9 CAR24848.1 - 0.00016 20.6 0.5 0.00026 19.9 0.5 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 CAR24848.1 - 0.00022 20.3 0.5 0.00039 19.5 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR24848.1 - 0.0031 16.9 0.1 0.0061 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR24848.1 - 0.0077 16.2 0.3 0.29 11.0 0.4 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family UBA PF00627.31 CAR24848.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain SIR2 PF02146.17 CAR24849.1 - 7e-36 123.8 0.0 9.2e-35 120.1 0.0 2.2 1 1 0 1 1 1 1 Sir2 family TSC22 PF01166.18 CAR24849.1 - 0.16 12.3 0.5 0.64 10.4 0.5 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family PX PF00787.24 CAR24850.1 - 0.00017 21.5 0.0 0.00036 20.5 0.0 1.4 1 0 0 1 1 1 1 PX domain Aldo_ket_red PF00248.21 CAR24852.1 - 6.5e-43 147.0 0.0 3.3e-33 115.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Pullulanase_Ins PF18494.1 CAR24852.1 - 0.031 14.7 0.0 0.078 13.5 0.0 1.6 2 0 0 2 2 2 0 Pullulanase Ins domain Mito_carr PF00153.27 CAR24853.1 - 7.8e-70 230.9 1.1 8.6e-24 83.3 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Ysc84 PF04366.12 CAR24853.1 - 0.00097 18.9 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ribosomal_L37ae PF01780.19 CAR24854.1 - 2.7e-40 136.3 8.9 3.1e-40 136.2 8.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-H2C2_2 PF13465.6 CAR24854.1 - 0.0029 18.0 0.9 0.68 10.5 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double domain Zn_Tnp_IS1595 PF12760.7 CAR24854.1 - 0.0052 16.7 2.3 0.0089 16.0 2.3 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 CAR24854.1 - 0.0056 16.8 3.2 0.0081 16.3 3.2 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rep_fac-A_C PF08646.10 CAR24854.1 - 0.0074 16.0 0.3 0.0084 15.9 0.3 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain CarbpepA_inh PF02977.15 CAR24854.1 - 0.042 13.7 4.2 0.075 12.8 1.0 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Sgf11 PF08209.11 CAR24854.1 - 0.042 13.4 0.4 0.48 10.0 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-ribbon_3 PF13248.6 CAR24854.1 - 0.054 12.9 1.3 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2175 PF09943.9 CAR24854.1 - 0.068 13.5 0.6 2.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) C1_2 PF03107.16 CAR24854.1 - 0.079 13.3 3.0 0.52 10.7 3.1 1.9 1 1 1 2 2 2 0 C1 domain C1_1 PF00130.22 CAR24854.1 - 0.1 12.5 2.0 0.15 12.0 2.0 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf_UBZ PF18439.1 CAR24854.1 - 1.2 8.8 3.2 8.3 6.1 0.0 2.5 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Sec23_Sec24 PF04810.15 CAR24854.1 - 1.3 9.1 4.8 7.2 6.8 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_10 PF16588.5 CAR24854.1 - 9 6.1 8.4 5.6 6.8 1.2 2.3 2 0 0 2 2 2 0 C2H2 zinc-finger Med6 PF04934.14 CAR24856.1 - 1.5e-53 180.1 0.1 1.9e-53 179.8 0.1 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component CoA_trans PF01144.23 CAR24856.1 - 0.029 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase Pro_isomerase PF00160.21 CAR24857.1 - 1e-46 159.1 0.1 1.3e-46 158.8 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AIM24 PF01987.17 CAR24858.1 - 2e-17 63.7 0.0 2.7e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PIG-F PF06699.11 CAR24859.1 - 8.7e-24 84.7 16.9 1e-22 81.2 16.9 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.19 CAR24859.1 - 0.055 13.1 5.6 0.13 11.8 5.7 1.7 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE CPSF_A PF03178.15 CAR24860.1 - 2.2e-90 303.2 0.9 3e-89 299.5 0.0 3.2 4 0 0 4 4 4 1 CPSF A subunit region MMS1_N PF10433.9 CAR24860.1 - 1.5e-19 70.1 1.0 2.7e-18 65.9 0.2 2.6 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term HPS3_N PF14761.6 CAR24860.1 - 0.1 12.1 1.1 38 3.7 0.0 4.1 5 0 0 5 5 5 0 Hermansky-Pudlak syndrome 3 AA_kinase PF00696.28 CAR24861.1 - 2.1e-37 129.0 0.6 3.3e-37 128.4 0.6 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CAR24861.1 - 1.5e-20 72.9 0.1 4e-20 71.6 0.1 1.8 1 0 0 1 1 1 1 PUA domain Pih1_fungal_CS PF18482.1 CAR24862.1 - 3.8e-22 78.6 0.0 6.2e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Pih1 CS domain PIH1 PF08190.12 CAR24862.1 - 5.3e-21 74.8 0.0 8.1e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain AATF-Che1 PF13339.6 CAR24863.1 - 1.1e-22 81.2 0.5 1.1e-22 81.2 0.5 2.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CAR24863.1 - 3.4e-22 78.8 0.0 1e-21 77.2 0.0 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Macoilin PF09726.9 CAR24863.1 - 0.16 10.5 10.7 0.26 9.8 10.7 1.3 1 0 0 1 1 1 0 Macoilin family Trypan_PARP PF05887.11 CAR24863.1 - 1.4 8.9 7.1 4.7 7.2 7.1 1.9 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) OSCP PF00213.18 CAR24864.1 - 2.3e-44 151.5 3.3 2.7e-44 151.3 3.3 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit FA_hydroxylase PF04116.13 CAR24865.1 - 7.1e-25 87.9 11.3 4.8e-24 85.2 8.2 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Mhr1 PF12829.7 CAR24866.1 - 1.3e-25 89.3 0.8 3.5e-25 87.9 0.4 1.9 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Peptidase_S13 PF02113.15 CAR24866.1 - 0.078 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family TBPIP PF07106.13 CAR24866.1 - 0.1 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Sec23_trunk PF04811.15 CAR24867.1 - 3.9e-12 46.3 0.0 1.3e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CAR24867.1 - 3e-07 31.1 0.3 7.9e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain HDA2-3 PF11496.8 CAR24868.1 - 1.4e-66 224.6 0.5 1.4e-66 224.6 0.5 1.7 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Latarcin PF10279.9 CAR24868.1 - 0.56 10.6 7.6 0.51 10.8 5.8 2.0 1 1 0 1 1 1 0 Latarcin precursor Pyridoxal_deC PF00282.19 CAR24869.1 - 4.1e-25 88.3 0.0 1.3e-24 86.7 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CAR24869.1 - 5.2e-10 38.8 0.0 3.9e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CAR24869.1 - 9.8e-08 31.7 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 CAR24869.1 - 0.00018 20.4 0.0 0.0003 19.6 0.0 1.3 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Brr6_like_C_C PF10104.9 CAR24870.1 - 2.3e-42 143.9 0.3 4e-42 143.2 0.3 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Aldedh PF00171.22 CAR24871.1 - 1.5e-101 340.2 0.0 1.8e-101 340.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNB PF00773.19 CAR24872.1 - 3e-60 204.3 0.6 5.7e-60 203.3 0.6 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CAR24872.1 - 1e-25 89.5 0.1 3.4e-25 87.9 0.1 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CAR24872.1 - 3.3e-22 78.6 0.0 1.2e-21 76.9 0.0 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CAR24872.1 - 2.1e-06 27.8 0.0 0.0002 21.5 0.0 3.0 3 0 0 3 3 3 1 Cold shock domain Rrp44_CSD1 PF17216.3 CAR24872.1 - 9.1e-06 25.5 0.2 2.6e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CAR24872.1 - 0.0072 16.0 0.1 2.2 8.0 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain Rrp44_S1 PF17215.3 CAR24872.1 - 0.097 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 S1 domain RRF PF01765.19 CAR24873.1 - 7.1e-42 143.1 7.7 1.1e-41 142.5 7.7 1.3 1 0 0 1 1 1 1 Ribosome recycling factor DUF2884 PF11101.8 CAR24873.1 - 0.0067 16.0 2.1 0.0087 15.6 1.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2884) Syntaxin PF00804.25 CAR24873.1 - 0.021 14.5 5.2 0.048 13.3 5.2 1.5 1 0 0 1 1 1 0 Syntaxin NYD-SP28 PF14772.6 CAR24873.1 - 0.044 13.8 4.4 0.1 12.6 4.4 1.7 1 0 0 1 1 1 0 Sperm tail ArAE_1_C PF11728.8 CAR24873.1 - 0.049 13.6 1.4 0.1 12.6 1.4 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain DNA_repr_REX1B PF14966.6 CAR24873.1 - 0.063 13.9 1.4 0.15 12.8 1.4 1.6 1 0 0 1 1 1 0 DNA repair REX1-B Fzo_mitofusin PF04799.13 CAR24873.1 - 0.18 11.3 2.6 0.32 10.5 2.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region DASH_Duo1 PF08651.10 CAR24873.1 - 0.27 11.0 3.7 0.16 11.7 1.6 1.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF16 PF01519.16 CAR24873.1 - 0.82 10.2 10.8 0.088 13.3 6.3 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4771 PF15995.5 CAR24873.1 - 0.89 9.8 4.4 3 8.1 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) IZUMO PF15005.6 CAR24873.1 - 4.6 7.7 8.3 2.1 8.9 4.6 2.2 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Aldedh PF00171.22 CAR24874.1 - 2e-129 432.1 0.0 2.4e-129 431.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family V-ATPase_G PF03179.15 CAR24875.1 - 5.2e-32 110.5 10.0 5.9e-32 110.3 10.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 CAR24875.1 - 0.00051 20.4 7.2 0.00072 19.9 7.2 1.2 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3164 PF11363.8 CAR24875.1 - 0.0023 17.6 3.0 0.0026 17.4 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3164) DUF3552 PF12072.8 CAR24875.1 - 0.0065 15.9 7.5 0.0065 15.9 7.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) SASP PF00269.20 CAR24875.1 - 0.015 15.3 0.8 0.027 14.5 0.8 1.4 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type ATP-synt_B PF00430.18 CAR24875.1 - 0.015 15.4 10.5 0.015 15.4 10.5 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1666 PF07891.12 CAR24875.1 - 0.13 11.9 4.0 0.12 12.1 3.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1666) RNA_pol_Rpc4 PF05132.14 CAR24875.1 - 0.25 11.8 3.1 0.3 11.5 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNase_J_C PF17770.1 CAR24875.1 - 7.1 7.8 6.6 5.8 8.0 3.1 2.0 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain zf-HIT PF04438.16 CAR24876.1 - 1.2e-07 31.4 11.4 2.1e-07 30.7 11.4 1.4 1 0 0 1 1 1 1 HIT zinc finger PolC_DP2 PF03833.13 CAR24876.1 - 0.046 11.6 4.5 0.061 11.2 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nop14 PF04147.12 CAR24876.1 - 1.3 7.1 9.5 1.8 6.7 9.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CAR24876.1 - 7.5 4.7 9.7 12 4.1 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Cyt-b5 PF00173.28 CAR24877.1 - 1.9e-14 53.6 0.0 4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 CAR24877.1 - 2.6e-08 34.0 9.1 1e-07 32.1 9.1 2.2 1 1 0 1 1 1 1 Fatty acid desaturase SRX PF09201.10 CAR24878.1 - 8.9e-58 194.3 0.2 2.3e-57 193.0 0.2 1.8 1 0 0 1 1 1 1 SRX, signal recognition particle receptor alpha subunit SRP54 PF00448.22 CAR24878.1 - 2e-46 158.1 0.1 6.9e-44 149.8 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CAR24878.1 - 5e-08 33.2 0.4 1.1e-07 32.0 0.4 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CAR24878.1 - 4.3e-07 30.0 0.1 1.4e-06 28.4 0.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 CAR24878.1 - 1.5e-06 27.4 0.1 4.7e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CAR24878.1 - 0.00012 22.1 0.0 0.00069 19.7 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CAR24878.1 - 0.00054 19.2 0.0 0.11 11.7 0.0 2.4 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CAR24878.1 - 0.0011 18.9 0.1 0.0084 16.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR24878.1 - 0.017 15.4 0.0 0.071 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 CAR24878.1 - 0.032 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 CAR24878.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAR24878.1 - 0.1 13.0 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 CAR24878.1 - 0.7 9.9 4.2 1.3 9.1 0.2 2.9 3 1 0 3 3 3 0 Helicase HerA, central domain DEAD PF00270.29 CAR24879.1 - 8.8e-24 84.2 0.0 3.8e-23 82.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.10 CAR24879.1 - 4.2e-19 69.1 0.2 1.1e-18 67.8 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 CAR24879.1 - 7.2e-13 48.9 0.1 2.6e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR24879.1 - 2.7e-08 34.0 0.0 5.7e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CAR24879.1 - 1.2e-05 25.7 1.3 2.7e-05 24.5 1.3 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like CTD_bind PF04818.13 CAR24880.1 - 7.2e-19 68.4 0.0 2.4e-18 66.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. DUF4686 PF15742.5 CAR24880.1 - 0.0052 16.0 3.2 0.0052 16.0 3.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) CTK3 PF12243.8 CAR24880.1 - 0.01 15.8 0.3 0.028 14.4 0.1 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 SwrA PF17423.2 CAR24880.1 - 0.069 13.1 0.7 0.17 11.9 0.1 2.0 2 0 0 2 2 2 0 Swarming motility protein DUF1938 PF09153.10 CAR24880.1 - 0.081 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) Med20 PF08612.11 CAR24881.1 - 4e-46 157.2 0.0 4.4e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex HGTP_anticodon2 PF12745.7 CAR24882.1 - 7.7e-89 297.7 1.5 7.7e-89 297.7 1.5 2.7 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 CAR24882.1 - 7e-69 232.1 7.2 6.2e-41 140.5 0.1 4.3 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24882.1 - 6.2e-38 130.6 0.0 6.1e-21 74.9 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 CAR24882.1 - 1.4e-18 67.3 2.6 7.4e-18 64.9 2.6 2.4 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 CAR24882.1 - 4.2e-11 42.7 0.0 8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase FTA2 PF13095.6 CAR24882.1 - 0.0063 16.2 0.6 2.5 7.7 0.0 3.7 3 1 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAR24882.1 - 0.073 12.4 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 0 Kinase-like UQ_con PF00179.26 CAR24882.1 - 0.11 12.2 0.0 0.34 10.5 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme APH PF01636.23 CAR24882.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAP2 PF01569.21 CAR24883.1 - 1.4e-23 83.2 1.2 1.7e-23 82.9 0.2 1.6 2 0 0 2 2 2 1 PAP2 superfamily LptF_LptG PF03739.14 CAR24883.1 - 0.27 10.0 2.8 0.49 9.2 0.1 2.1 1 1 1 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG RseC_MucC PF04246.12 CAR24883.1 - 0.29 11.1 2.5 0.32 11.0 0.9 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF836 PF05768.14 CAR24884.1 - 1.1e-18 67.5 0.1 1.2e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CAR24884.1 - 0.0015 18.7 0.1 0.0035 17.5 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Inositol_P PF00459.25 CAR24885.1 - 1.3e-71 241.3 0.0 1.5e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MAGE PF01454.19 CAR24886.1 - 1.6e-38 132.6 0.0 2.7e-38 131.8 0.0 1.3 1 1 0 1 1 1 1 MAGE family FAD_binding_1 PF00667.20 CAR24887.1 - 8.2e-72 241.4 0.0 1.4e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CAR24887.1 - 5.1e-33 114.3 0.4 9.9e-33 113.4 0.4 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CAR24887.1 - 2.9e-22 79.4 0.0 1.1e-21 77.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.10 CAR24887.1 - 0.00015 20.8 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) Flavodoxin_5 PF12724.7 CAR24887.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain DUF155 PF02582.14 CAR24888.1 - 1.8e-42 145.4 0.2 3.1e-42 144.7 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 60KD_IMP PF02096.20 CAR24888.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein RCC1_2 PF13540.6 CAR24888.1 - 0.29 11.0 1.0 4.8 7.1 0.3 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat RNase_PH_C PF03725.15 CAR24889.1 - 4.8e-19 68.2 0.3 1.4e-18 66.7 0.1 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 CAR24889.1 - 5.5e-19 69.0 0.0 9.9e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_H2-Ydr279 PF09468.10 CAR24890.1 - 2.8e-23 82.9 0.1 9.3e-23 81.2 0.1 1.9 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CAR24890.1 - 2.2e-11 43.8 0.0 4.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain ORC4_C PF14629.6 CAR24890.1 - 0.004 16.5 0.2 0.0064 15.9 0.2 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus Inositol_P PF00459.25 CAR24892.1 - 1.6e-67 227.9 0.0 1.8e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M1 PF01433.20 CAR24893.1 - 1.3e-87 293.0 4.4 5.4e-87 290.9 3.9 2.2 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CAR24893.1 - 2.7e-83 280.1 4.2 2.9e-82 276.7 0.2 2.7 3 1 0 3 3 3 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CAR24893.1 - 1.5e-52 178.5 0.7 2.9e-52 177.6 0.7 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MFS_1 PF07690.16 CAR24894.1 - 2.1e-36 125.6 37.8 2.1e-36 125.6 37.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR24894.1 - 6.9e-07 28.5 34.4 1.3e-06 27.6 34.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Wzy_C_2 PF11846.8 CAR24894.1 - 1.2 9.1 4.6 1.2 9.1 2.2 2.2 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal FSH1 PF03959.13 CAR24895.1 - 1.5e-62 211.0 0.0 1.7e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CAR24895.1 - 0.00038 20.3 0.2 0.19 11.5 0.1 2.2 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CAR24895.1 - 0.055 13.4 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 CAR24895.1 - 0.069 13.7 0.0 3.9 8.0 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Nramp PF01566.18 CAR24896.1 - 8.3e-92 307.9 15.5 1.6e-91 307.0 15.5 1.4 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Calcipressin PF04847.12 CAR24897.1 - 3.1e-19 69.5 0.5 4.2e-19 69.0 0.5 1.3 1 1 0 1 1 1 1 Calcipressin COX5A PF02284.16 CAR24898.1 - 3.6e-40 136.1 1.8 5.1e-40 135.6 1.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.13 CAR24898.1 - 0.0032 18.1 0.9 0.025 15.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF488 HTH_19 PF12844.7 CAR24898.1 - 0.071 13.1 1.6 0.39 10.8 0.7 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Elf1 PF05129.13 CAR24899.1 - 4e-30 103.7 0.7 5.6e-30 103.2 0.7 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF4820 PF16091.5 CAR24899.1 - 1.2 8.4 8.7 2.9 7.2 8.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) Ribosomal_L1 PF00687.21 CAR24900.1 - 2.5e-36 125.4 4.2 2.5e-36 125.4 4.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Hamartin PF04388.12 CAR24900.1 - 0.098 11.3 11.5 0.014 14.2 7.7 1.4 2 0 0 2 2 2 0 Hamartin protein GCR1_C PF12550.8 CAR24901.1 - 4.5e-16 58.9 0.8 9.1e-16 58.0 0.8 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes QIL1 PF15884.5 CAR24901.1 - 0.11 13.1 0.0 0.91 10.2 0.0 2.4 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 DUF3791 PF12668.7 CAR24901.1 - 0.13 12.4 0.1 0.39 10.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) MatE PF01554.18 CAR24902.1 - 3.5e-65 218.6 27.0 1.7e-37 128.6 8.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CAR24902.1 - 0.0012 19.0 7.2 0.0012 19.0 7.2 3.4 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain PIF1 PF05970.14 CAR24903.1 - 7.6e-59 199.7 2.7 4.3e-47 161.0 0.2 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CAR24903.1 - 1.9e-21 76.7 0.0 5.1e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR24903.1 - 7.6e-09 36.1 0.0 1.5e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CAR24903.1 - 3.4e-05 23.5 0.1 9.5e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 CAR24903.1 - 0.0002 19.5 0.4 0.0023 16.0 0.0 2.4 2 1 1 3 3 3 1 Helicase AAA_22 PF13401.6 CAR24903.1 - 0.00036 20.8 0.1 0.0018 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 CAR24903.1 - 0.0041 16.1 0.0 0.0072 15.3 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 CAR24903.1 - 0.007 16.8 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CAR24903.1 - 0.0075 16.0 0.1 5.8 6.6 0.0 3.0 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CAR24903.1 - 0.0082 15.4 0.7 0.03 13.6 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CAR24903.1 - 0.012 15.0 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.6 CAR24903.1 - 0.013 15.3 0.1 0.07 13.0 0.1 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 CAR24903.1 - 0.014 15.8 0.1 0.036 14.4 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CAR24903.1 - 0.018 14.1 0.1 0.018 14.1 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_11 PF13086.6 CAR24903.1 - 0.021 14.6 0.2 0.46 10.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 CAR24903.1 - 0.054 13.3 0.3 0.17 11.7 0.3 1.8 1 1 0 1 1 1 0 Helicase ResIII PF04851.15 CAR24903.1 - 0.094 12.7 0.0 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 CAR24903.1 - 0.098 13.2 0.1 0.43 11.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Pkinase PF00069.25 CAR24904.1 - 1.5e-65 221.2 0.3 4.3e-65 219.7 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR24904.1 - 9.7e-31 107.0 0.0 1.9e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR24904.1 - 0.0028 16.7 0.2 0.0028 16.7 0.2 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CAR24904.1 - 0.0077 16.2 1.3 0.11 12.4 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.32 CAR24904.1 - 0.011 16.6 0.0 0.045 14.6 0.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat Kdo PF06293.14 CAR24904.1 - 0.026 13.9 0.0 0.062 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Spt20 PF12090.8 CAR24904.1 - 0.21 11.2 11.8 0.37 10.4 11.8 1.3 1 0 0 1 1 1 0 Spt20 family PhzC-PhzF PF02567.16 CAR24905.1 - 3.8e-63 213.6 0.0 4.3e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein UPF0020 PF01170.18 CAR24905.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DAP_epimerase PF01678.19 CAR24905.1 - 0.03 14.5 0.0 0.18 12.0 0.0 2.2 2 1 0 2 2 2 0 Diaminopimelate epimerase DPPIV_N PF00930.21 CAR24906.1 - 2.5e-109 365.3 2.9 3.3e-109 364.9 2.9 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CAR24906.1 - 2.5e-53 180.7 1.3 4e-53 180.0 1.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CAR24906.1 - 0.00018 22.2 0.0 0.024 15.2 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CAR24906.1 - 0.0052 16.6 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase RPN1_RPN2_N PF17781.1 CAR24907.1 - 2.8e-115 385.0 0.2 6.7e-115 383.7 0.2 1.7 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CAR24907.1 - 1.2e-29 102.1 0.0 2.3e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CAR24907.1 - 3.3e-26 90.3 11.9 6.4e-07 29.5 0.2 8.6 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CAR24907.1 - 0.008 16.5 0.6 4.8 7.6 0.0 4.0 4 1 0 4 4 4 1 HEAT repeats ATP-synt_C PF00137.21 CAR24908.1 - 3.2e-27 94.7 31.3 2.2e-16 59.9 13.2 2.4 2 0 0 2 2 2 2 ATP synthase subunit C DUF3671 PF12420.8 CAR24908.1 - 2.2 8.4 4.7 0.57 10.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function GHMP_kinases_N PF00288.26 CAR24909.1 - 6.4e-10 39.1 0.0 1.5e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAR24909.1 - 0.0015 18.8 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16_C PF05193.21 CAR24910.1 - 1.3e-46 159.0 0.0 4.8e-46 157.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR24910.1 - 7.4e-45 152.6 0.2 4.9e-43 146.7 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 CAR24910.1 - 0.041 13.0 1.9 0.99 8.5 0.1 2.8 2 1 1 3 3 3 0 Peptidase M16C associated Myosin_head PF00063.21 CAR24911.1 - 4.2e-262 871.3 11.8 4.2e-262 871.3 11.8 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) BRE1 PF08647.11 CAR24911.1 - 0.00068 19.7 16.8 0.00068 19.7 16.8 12.2 6 4 6 13 13 13 2 BRE1 E3 ubiquitin ligase YabA PF06156.13 CAR24911.1 - 0.0052 17.4 4.6 0.0052 17.4 4.6 12.6 5 4 3 11 11 11 3 Initiation control protein YabA TSC22 PF01166.18 CAR24911.1 - 0.031 14.6 0.4 0.031 14.6 0.4 9.9 12 0 0 12 12 12 0 TSC-22/dip/bun family AAA_22 PF13401.6 CAR24911.1 - 0.05 13.9 3.4 0.18 12.1 0.0 3.7 3 0 0 3 3 3 0 AAA domain Erf4 PF10256.9 CAR24911.1 - 0.095 12.8 4.0 0.63 10.2 0.3 3.8 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Myosin_N PF02736.19 CAR24911.1 - 0.11 12.3 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CAR24911.1 - 0.18 12.2 0.0 0.18 12.2 0.0 5.1 5 1 0 5 5 5 0 AAA ATPase domain F-box-like PF12937.7 CAR24912.1 - 0.0015 18.4 0.2 0.008 16.0 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 CAR24912.1 - 0.012 15.4 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box DUF5637 PF18687.1 CAR24912.1 - 0.046 13.7 0.7 0.11 12.5 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5637) Ras PF00071.22 CAR24913.1 - 8.7e-25 87.2 0.1 1.8e-20 73.2 0.1 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CAR24913.1 - 0.00024 21.3 0.0 0.02 15.1 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CAR24913.1 - 0.0051 16.4 0.1 0.0099 15.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 CAR24913.1 - 0.054 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CAR24913.1 - 0.064 13.0 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CAR24913.1 - 0.075 13.4 0.3 0.18 12.2 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CAR24913.1 - 0.096 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Ribosomal_S27e PF01667.17 CAR24915.1 - 1e-29 102.0 2.6 1.3e-29 101.6 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CAR24915.1 - 0.0056 16.2 3.8 0.0084 15.6 3.8 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.21 CAR24915.1 - 0.014 15.6 0.6 0.016 15.4 0.6 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Rsm22 PF09243.10 CAR24916.1 - 9.8e-27 93.9 0.0 5.5e-09 35.7 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CAR24916.1 - 0.006 16.4 0.0 0.023 14.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain SRPRB PF09439.10 CAR24917.1 - 9.4e-64 214.2 0.0 1.2e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CAR24917.1 - 9.7e-08 31.7 0.0 1.3e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR24917.1 - 0.0002 21.4 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nup192 PF11894.8 CAR24918.1 - 0 1617.9 48.4 0 1617.8 48.4 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nsp1_C PF05064.13 CAR24919.1 - 8e-39 132.0 1.3 8e-39 132.0 1.3 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region Muted PF14942.6 CAR24919.1 - 0.021 15.2 3.3 0.04 14.3 3.3 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein PRP9_N PF16958.5 CAR24919.1 - 0.37 10.8 3.1 0.88 9.6 3.0 1.6 1 1 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus APG6_N PF17675.1 CAR24919.1 - 0.88 10.1 10.4 1.6 9.2 10.4 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Cupin_8 PF13621.6 CAR24920.1 - 0.053 13.2 0.4 0.21 11.2 0.4 2.0 1 1 0 1 1 1 0 Cupin-like domain RabGAP-TBC PF00566.18 CAR24921.1 - 4.6e-22 78.7 0.3 6.6e-22 78.2 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain His_Phos_1 PF00300.22 CAR24922.1 - 2.7e-36 125.1 0.1 5e-28 98.1 0.2 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Carb_kinase PF01256.17 CAR24923.1 - 7.5e-60 202.4 0.0 2.1e-59 200.9 0.0 1.6 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CAR24923.1 - 4.8e-05 22.8 0.0 8.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase NAD_binding_1 PF00175.21 CAR24924.1 - 2.2e-27 95.9 0.0 3.2e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAR24924.1 - 9.6e-27 93.2 0.0 1.8e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAR24924.1 - 4.4e-06 26.9 0.0 0.0005 20.2 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DBR1 PF05011.13 CAR24925.1 - 5.4e-09 36.6 0.0 9.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CAR24925.1 - 2.2e-05 25.1 0.5 3.8e-05 24.3 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_2 PF00890.24 CAR24926.1 - 4.9e-123 411.3 5.0 6.2e-123 411.0 5.0 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CAR24926.1 - 1.9e-42 144.2 0.3 2.9e-42 143.7 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 CAR24926.1 - 1.6e-06 27.5 0.4 0.0018 17.4 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CAR24926.1 - 2.8e-05 23.5 1.2 0.0002 20.7 0.6 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAR24926.1 - 0.00026 20.3 0.9 0.044 13.0 0.1 2.8 3 0 0 3 3 3 2 Thi4 family FAD_binding_3 PF01494.19 CAR24926.1 - 0.001 18.4 0.6 0.0037 16.6 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CAR24926.1 - 0.0093 15.6 4.7 0.03 13.9 4.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CAR24926.1 - 0.076 11.7 0.3 0.3 9.7 0.1 1.9 2 0 0 2 2 2 0 HI0933-like protein Aa_trans PF01490.18 CAR24927.1 - 1.9e-95 320.0 30.7 2.3e-95 319.7 30.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CAR24927.1 - 0.0012 17.8 27.1 0.0012 17.8 27.1 2.0 1 1 1 2 2 2 1 Amino acid permease AAA PF00004.29 CAR24928.1 - 6e-40 136.7 0.0 1.6e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR24928.1 - 1.3e-06 28.1 0.0 3.6e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CAR24928.1 - 4.9e-05 23.3 0.0 0.00017 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR24928.1 - 5.6e-05 23.4 0.0 0.0029 17.9 0.0 2.6 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 CAR24928.1 - 0.00016 22.1 0.1 0.0039 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CAR24928.1 - 0.00042 20.5 0.0 0.00097 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CAR24928.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CAR24928.1 - 0.0037 17.0 0.0 0.0069 16.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR24928.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAR24928.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAR24928.1 - 0.027 15.0 0.0 0.068 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAR24928.1 - 0.031 14.0 0.1 0.097 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAR24928.1 - 0.035 14.5 0.0 0.085 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CAR24928.1 - 0.044 13.3 0.0 0.099 12.1 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 CAR24928.1 - 0.047 13.6 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CAR24928.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CAR24928.1 - 0.052 12.8 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CAR24928.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CAR24928.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_pol_Rbc25 PF08292.12 CAR24929.1 - 6e-52 175.3 0.5 8e-52 174.9 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CAR24929.1 - 1e-19 70.7 0.0 1.5e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CAR24929.1 - 0.0029 17.9 0.0 0.0088 16.4 0.0 1.9 1 1 0 1 1 1 1 S1 RNA binding domain LTV PF04180.14 CAR24930.1 - 2.3e-109 366.6 29.8 2.8e-109 366.4 29.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein HEPN_Toprim_N PF18871.1 CAR24930.1 - 2.7 7.9 15.9 0.33 10.8 4.6 2.7 3 0 0 3 3 3 0 HEPN/Toprim N-terminal domain 1 DUF3294 PF07957.11 CAR24931.1 - 9.2e-94 313.1 5.1 1e-93 313.0 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) AF0941-like PF14591.6 CAR24931.1 - 0.1 13.2 0.2 0.1 13.2 0.2 2.4 2 0 0 2 2 2 0 AF0941-like PUF PF00806.19 CAR24932.1 - 1.3e-29 100.1 3.8 0.00067 19.2 0.0 9.2 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat Cpn60_TCP1 PF00118.24 CAR24933.1 - 5.9e-154 513.3 7.7 6.7e-154 513.1 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PucR PF07905.11 CAR24933.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Purine catabolism regulatory protein-like family Vps53_N PF04100.12 CAR24934.1 - 4.1e-87 292.6 3.4 4.1e-87 292.6 3.4 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal VPS53_C PF16854.5 CAR24934.1 - 3.4e-73 245.9 0.1 6.4e-73 244.9 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus Scytalone_dh PF02982.14 CAR24934.1 - 0.013 15.3 0.0 0.078 12.8 0.0 2.1 2 0 0 2 2 2 0 Scytalone dehydratase HORMA PF02301.18 CAR24935.1 - 2e-24 86.4 0.4 2.9e-24 85.8 0.4 1.2 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.9 CAR24935.1 - 0.0048 16.6 0.0 0.0093 15.7 0.0 1.5 2 0 0 2 2 2 1 Autophagy-related protein 13 bacHORMA_2 PF18173.1 CAR24935.1 - 0.0089 15.9 0.1 0.024 14.5 0.0 1.7 2 1 0 2 2 2 1 Bacterial HORMA domain 2 DUF3440 PF11922.8 CAR24935.1 - 0.023 14.4 0.1 0.035 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Cyclin_N PF00134.23 CAR24936.1 - 6.6e-15 55.0 6.4 6.9e-13 48.5 3.6 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain MRP-63 PF14978.6 CAR24936.1 - 0.09 13.4 0.3 0.36 11.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 DEAD PF00270.29 CAR24937.1 - 3.4e-47 160.5 0.1 1.3e-46 158.5 0.1 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR24937.1 - 2.3e-24 85.9 0.0 6.6e-24 84.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR24937.1 - 8.2e-20 70.8 0.0 1.8e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAR24937.1 - 4.9e-08 33.2 1.8 8.9e-08 32.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAD_binding_9 PF08021.11 CAR24937.1 - 0.023 14.9 0.3 3.1 8.0 0.0 3.3 3 0 0 3 3 3 0 Siderophore-interacting FAD-binding domain DUF1492 PF07374.11 CAR24937.1 - 0.16 12.1 1.7 0.74 10.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) FHA PF00498.26 CAR24938.1 - 6.8e-14 52.0 0.0 1.9e-13 50.6 0.0 1.8 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CAR24938.1 - 0.026 14.9 0.0 0.079 13.3 0.0 1.8 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain HSP70 PF00012.20 CAR24939.1 - 7.3e-263 873.2 13.8 8.3e-263 873.0 13.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR24939.1 - 4.1e-17 62.0 1.0 6.6e-16 58.0 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CAR24939.1 - 0.003 17.9 4.9 0.79 10.2 0.2 3.7 3 2 0 3 3 3 1 Cell division protein FtsA Sec34 PF04136.15 CAR24939.1 - 0.0033 17.3 0.7 0.0071 16.2 0.7 1.5 1 0 0 1 1 1 1 Sec34-like family Hydantoinase_A PF01968.18 CAR24939.1 - 0.0065 15.8 1.6 0.25 10.5 0.1 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Radial_spoke_3 PF06098.11 CAR24939.1 - 0.027 13.8 2.0 0.055 12.7 2.0 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 BcrAD_BadFG PF01869.20 CAR24939.1 - 0.028 13.9 0.2 2.1 7.7 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family dCMP_cyt_deam_1 PF00383.23 CAR24940.1 - 6.7e-24 83.7 0.1 9.8e-24 83.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR24940.1 - 7.6e-18 64.6 0.1 1.1e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CAR24940.1 - 9.1e-05 22.6 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 CAR24940.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 CAR24940.1 - 0.00042 20.5 0.0 0.00063 19.9 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 CAR24940.1 - 0.0024 17.9 0.0 0.0037 17.3 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 Bd3614-deam PF14439.6 CAR24940.1 - 0.0037 17.3 0.1 0.012 15.6 0.1 1.8 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC3 PF18771.1 CAR24940.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 Inv-AAD PF18785.1 CAR24940.1 - 0.03 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase APOBEC4_like PF18774.1 CAR24940.1 - 0.033 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase Toxin-deaminase PF14424.6 CAR24940.1 - 0.039 14.1 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases PX PF00787.24 CAR24941.1 - 1.4e-24 86.3 0.6 5.2e-24 84.4 0.6 2.0 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CAR24941.1 - 0.0024 17.5 5.2 0.0024 17.5 5.2 2.6 2 1 0 2 2 2 1 Vps5 C terminal like Gp-FAR-1 PF05823.12 CAR24941.1 - 0.004 17.5 1.0 0.004 17.5 1.0 2.4 2 1 0 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) aGPT-Pplase1 PF18723.1 CAR24941.1 - 0.021 14.3 0.2 0.053 13.0 0.2 1.8 1 0 0 1 1 1 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 TolA_bind_tri PF16331.5 CAR24941.1 - 0.035 14.2 0.5 0.33 11.1 0.1 2.7 2 0 0 2 2 2 0 TolA binding protein trimerisation ACR_tran PF00873.19 CAR24941.1 - 0.066 10.9 0.3 0.092 10.4 0.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family NPV_P10 PF05531.12 CAR24941.1 - 0.069 13.6 5.4 5.4 7.5 0.0 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 CAR24941.1 - 0.12 12.4 7.6 0.13 12.3 0.7 2.9 2 1 0 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 CAR24941.1 - 0.13 11.6 2.7 0.41 9.9 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RNase_T PF00929.24 CAR24941.1 - 0.16 12.5 3.0 0.17 12.4 0.3 2.4 3 1 1 4 4 2 0 Exonuclease T3SSipB PF16535.5 CAR24941.1 - 0.24 11.9 6.0 0.19 12.2 0.2 2.7 1 1 0 2 2 2 0 Type III cell invasion protein SipB Jnk-SapK_ap_N PF09744.9 CAR24941.1 - 1.2 9.4 15.5 2.3 8.4 2.4 2.7 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF948 PF06103.11 CAR24941.1 - 1.4 9.3 4.9 5.4 7.4 0.4 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) STAT_alpha PF01017.20 CAR24941.1 - 1.7 8.5 8.3 0.12 12.2 0.7 2.8 3 2 0 3 3 2 0 STAT protein, all-alpha domain Baculo_PEP_C PF04513.12 CAR24941.1 - 1.9 8.5 3.7 12 5.9 0.1 2.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CAR24941.1 - 2 8.5 8.1 4.7 7.3 2.9 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 CAR24941.1 - 2 7.8 16.0 1.4 8.3 9.3 2.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4618) Fez1 PF06818.15 CAR24941.1 - 2.9 8.3 12.8 11 6.4 4.7 2.4 1 1 1 2 2 2 0 Fez1 LPP PF04728.13 CAR24941.1 - 3 8.3 9.7 2 8.9 0.1 4.2 3 1 1 4 4 3 0 Lipoprotein leucine-zipper DUF641 PF04859.12 CAR24941.1 - 3.3 8.0 9.8 0.68 10.3 0.5 3.0 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) APG6_N PF17675.1 CAR24941.1 - 5.1 7.6 15.0 0.32 11.5 2.5 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region RPW8 PF05659.11 CAR24941.1 - 8.4 6.1 8.0 22 4.7 4.1 3.1 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fungal_trans PF04082.18 CAR24943.1 - 9.1e-44 149.5 1.0 4.6e-43 147.2 1.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR24943.1 - 1.8e-10 40.8 10.0 3.5e-10 39.8 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4568 PF15132.6 CAR24943.1 - 0.057 12.8 0.1 0.2 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4568) Mito_carr PF00153.27 CAR24944.1 - 3.1e-55 184.1 1.3 3.7e-19 68.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_15 PF01793.16 CAR24945.1 - 4.3e-126 420.6 4.4 5.3e-126 420.3 4.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mannosyl_trans3 PF11051.8 CAR24947.1 - 3.7e-69 233.1 0.0 4.9e-69 232.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Ribosomal_S7e PF01251.18 CAR24949.1 - 6.8e-81 270.4 2.0 7.6e-81 270.3 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Rib_5-P_isom_A PF06026.14 CAR24950.1 - 3.1e-58 196.2 0.0 4.1e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Arf PF00025.21 CAR24951.1 - 3.6e-69 231.7 0.3 4.1e-69 231.5 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAR24951.1 - 5.4e-15 55.7 0.0 7.7e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAR24951.1 - 1.1e-14 54.2 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CAR24951.1 - 5.8e-13 48.7 0.8 2e-08 33.8 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CAR24951.1 - 1e-12 48.0 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CAR24951.1 - 1.9e-10 40.5 0.1 2.4e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR24951.1 - 2.1e-05 24.6 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CAR24951.1 - 0.18 11.1 0.9 0.36 10.1 0.2 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AMP-binding PF00501.28 CAR24952.1 - 1e-39 136.3 0.0 6.8e-12 44.7 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.11 CAR24952.1 - 3.2e-12 47.2 0.2 9.5e-12 45.7 0.2 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain Mem_trans PF03547.18 CAR24953.1 - 5.1e-29 100.8 0.5 7.1e-29 100.4 0.5 1.2 1 0 0 1 1 1 1 Membrane transport protein RELT PF12606.8 CAR24953.1 - 0.13 11.2 0.1 0.13 11.2 0.1 2.2 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 DUF2183 PF09949.9 CAR24954.1 - 4.7e-30 103.9 0.0 1.7e-29 102.1 0.0 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 CAR24954.1 - 0.0025 17.3 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DFRP_C PF16543.5 CAR24955.1 - 2.9e-25 88.6 7.5 2.9e-25 88.6 7.5 3.5 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 CAR24955.1 - 2.4e-05 24.1 0.3 2.4e-05 24.1 0.3 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAR24955.1 - 9.1e-05 23.1 10.8 0.00091 19.9 2.1 3.1 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 CAR24955.1 - 0.00017 21.5 14.0 0.00021 21.2 4.1 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CAR24955.1 - 0.0025 17.6 8.3 0.045 13.6 1.0 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CAR24955.1 - 0.2 12.2 11.2 1.3 9.6 2.0 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CAR24955.1 - 0.25 11.5 7.3 0.81 9.9 0.2 2.9 2 1 1 3 3 3 0 Zinc-finger containing family PP2C PF00481.21 CAR24956.1 - 1.2e-43 149.6 0.0 3e-43 148.3 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3666 PF12408.8 CAR24956.1 - 0.2 10.9 0.0 0.53 9.5 0.0 1.7 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Ras PF00071.22 CAR24957.1 - 2.5e-59 199.5 0.0 3e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24957.1 - 3.4e-35 120.9 0.0 4.8e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24957.1 - 1.3e-17 63.8 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR24957.1 - 4.3e-06 26.2 0.0 5.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR24957.1 - 1.1e-05 25.4 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR24957.1 - 2.3e-05 24.0 0.0 3.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR24957.1 - 4.6e-05 23.4 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Ion_trans PF00520.31 CAR24958.1 - 8.1e-06 25.2 18.8 1.6e-05 24.2 18.8 1.5 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CAR24958.1 - 0.0049 15.6 10.7 0.045 12.4 10.7 2.3 1 1 0 1 1 1 1 Polycystin cation channel LRR19-TM PF15176.6 CAR24958.1 - 0.036 14.0 0.5 3.3 7.8 0.0 2.9 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain T3SSipB PF16535.5 CAR24958.1 - 0.092 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB NST1 PF13945.6 CAR24959.1 - 5.7e-13 49.4 12.3 5.7e-13 49.4 12.3 6.0 4 2 1 5 5 5 1 Salt tolerance down-regulator Ras PF00071.22 CAR24960.1 - 1e-50 171.5 0.0 1.2e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR24960.1 - 3.3e-22 78.9 0.0 5.9e-22 78.1 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR24960.1 - 2.4e-08 33.6 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CAR24960.1 - 0.011 15.5 0.0 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 CAR24960.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_21 PF13304.6 CAR24960.1 - 0.058 13.2 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRPRB PF09439.10 CAR24960.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DNA_topoisoIV PF00521.20 CAR24961.1 - 9.5e-124 413.5 3.0 9.7e-124 413.5 0.0 2.4 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CAR24961.1 - 9.6e-50 168.1 0.5 6.6e-49 165.4 0.5 2.6 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CAR24961.1 - 2.6e-27 95.4 5.7 6.9e-27 94.0 5.7 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CAR24961.1 - 4.6e-14 52.9 1.0 8.1e-13 48.9 0.0 2.9 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CAR24961.1 - 2.5e-07 30.9 0.3 1.2e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 Toprim domain DUF4484 PF14831.6 CAR24961.1 - 5.1 7.1 7.3 0.36 10.8 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) C2 PF00168.30 CAR24962.1 - 2.1e-67 223.9 1.6 2.1e-20 72.9 0.0 4.5 4 0 0 4 4 4 4 C2 domain kleA_kleC PF17383.2 CAR24962.1 - 0.57 10.5 3.1 4.7 7.6 2.3 2.7 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A PP_M1 PF03012.14 CAR24962.1 - 2.3 7.7 5.4 4.5 6.7 5.4 1.4 1 0 0 1 1 1 0 Phosphoprotein Snapin_Pallidin PF14712.6 CAR24963.1 - 0.00082 19.7 2.0 0.0012 19.3 2.0 1.2 1 0 0 1 1 1 1 Snapin/Pallidin DUF2390 PF09523.10 CAR24963.1 - 0.0063 16.8 1.0 0.008 16.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2390) Tmemb_cc2 PF10267.9 CAR24963.1 - 0.0069 15.6 1.6 0.0073 15.5 1.6 1.0 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein OST3_OST6 PF04756.13 CAR24964.1 - 2e-87 293.2 0.5 2.4e-87 293.0 0.5 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CAR24964.1 - 0.0052 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF1129 PF06570.11 CAR24964.1 - 0.01 15.3 0.3 0.01 15.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF5518 PF17647.1 CAR24964.1 - 0.44 10.7 11.2 3.8 7.7 11.2 2.4 1 1 0 1 1 1 0 Family of unknown function (DUF5518) MKT1_C PF12246.8 CAR24965.1 - 7e-61 205.5 0.8 2.8e-60 203.5 1.3 1.7 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CAR24965.1 - 5.4e-31 106.8 0.1 2.3e-30 104.8 0.1 2.2 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CAR24965.1 - 1.9e-20 73.2 0.0 5.3e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain Cpn60_TCP1 PF00118.24 CAR24966.1 - 6.6e-147 490.1 8.6 7.5e-147 489.9 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 CAR24966.1 - 0.17 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat EF-hand_4 PF12763.7 CAR24967.1 - 5.7e-48 161.2 1.9 2.2e-47 159.3 1.9 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 CAR24967.1 - 9.8e-40 136.9 0.5 2.4e-39 135.6 0.5 1.6 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 CAR24967.1 - 0.0027 17.2 0.8 0.025 14.1 2.0 2.1 2 0 0 2 2 2 1 EF hand SKG6 PF08693.10 CAR24968.1 - 5.5e-14 51.3 0.2 1.3e-13 50.1 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.12 CAR24968.1 - 1e-12 48.0 1.9 0.00061 19.9 0.0 4.2 4 0 0 4 4 4 3 Putative Ig domain RIFIN PF02009.16 CAR24968.1 - 9.2e-06 25.8 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Rifin TMEM154 PF15102.6 CAR24968.1 - 8.6e-05 22.5 0.9 0.00031 20.7 0.9 2.0 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 CAR24968.1 - 0.00031 20.6 0.3 0.00065 19.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2207 PF09972.9 CAR24968.1 - 0.00042 19.2 0.0 0.00059 18.7 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.18 CAR24968.1 - 0.0089 16.3 0.8 0.027 14.7 0.8 1.8 1 0 0 1 1 1 1 Glycophorin A Mid2 PF04478.12 CAR24968.1 - 0.016 15.0 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Stevor PF17410.2 CAR24968.1 - 0.072 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Orf78 PF06024.12 CAR24968.1 - 0.081 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF4366 PF14283.6 CAR24968.1 - 0.11 12.6 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CCDC106 PF15794.5 CAR24968.1 - 0.15 11.8 4.5 0.67 9.6 4.5 2.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 4HBT PF03061.22 CAR24969.1 - 3.7e-06 27.2 0.5 0.029 14.7 0.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Mito_carr PF00153.27 CAR24970.1 - 1.1e-62 208.0 2.9 2e-21 75.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CAR24970.1 - 8.9e-17 61.3 0.9 3.2e-11 43.5 0.2 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAR24970.1 - 2e-13 48.8 4.9 0.00067 19.0 0.0 4.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 CAR24970.1 - 1.8e-11 43.0 2.3 0.011 15.6 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CAR24970.1 - 1.2e-07 31.4 1.1 0.091 12.6 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CAR24970.1 - 4.6e-06 26.8 0.0 0.0013 19.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CAR24970.1 - 0.006 16.0 8.8 0.4 10.3 0.1 3.5 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 CAR24970.1 - 0.024 14.8 0.5 0.87 9.8 0.0 2.5 1 1 1 2 2 2 0 Dockerin type I domain HORMA PF02301.18 CAR24971.1 - 1.8e-11 44.1 0.3 3.9e-11 42.9 0.3 1.5 1 1 0 1 1 1 1 HORMA domain MutL_C PF08676.11 CAR24972.1 - 4.5e-25 88.1 0.0 8.7e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CAR24972.1 - 7.8e-24 83.6 0.2 2.3e-23 82.1 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CAR24972.1 - 2.8e-07 30.4 0.0 7.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAR24972.1 - 6.3e-05 23.5 0.3 0.00064 20.2 0.0 2.8 4 0 0 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S13 PF00416.22 CAR24973.1 - 1e-16 61.5 0.1 1.7e-14 54.3 0.1 2.2 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Tail_P2_I PF09684.10 CAR24973.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 Phage tail protein (Tail_P2_I) EOS1 PF12326.8 CAR24974.1 - 2.2e-60 203.6 7.4 2.2e-60 203.6 7.4 1.8 2 0 0 2 2 2 1 N-glycosylation protein Ubie_methyltran PF01209.18 CAR24975.1 - 2.5e-97 324.8 0.2 2.8e-97 324.6 0.2 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CAR24975.1 - 3.3e-12 46.9 0.0 7.5e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR24975.1 - 2.7e-10 40.8 0.0 5.5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR24975.1 - 4.5e-10 39.5 0.0 8.4e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR24975.1 - 2.3e-09 37.9 0.1 4e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR24975.1 - 2.4e-05 24.2 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CAR24975.1 - 0.029 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 CAR24975.1 - 0.05 13.4 0.0 0.49 10.2 0.0 2.1 1 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_28 PF02636.17 CAR24975.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Tropomyosin_1 PF12718.7 CAR24976.1 - 1.3e-54 184.2 43.7 1.6e-54 184.0 43.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CAR24976.1 - 3.6e-07 29.8 39.4 0.00079 18.9 17.7 2.1 1 1 1 2 2 2 2 Tropomyosin Laminin_II PF06009.12 CAR24976.1 - 3.7e-05 23.8 22.7 0.0036 17.3 11.1 2.1 1 1 1 2 2 2 2 Laminin Domain II CENP-F_leu_zip PF10473.9 CAR24976.1 - 6e-05 23.1 44.5 0.00032 20.7 8.0 2.4 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 CAR24976.1 - 6.3e-05 22.0 38.8 0.0042 16.0 16.7 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein KLRAQ PF10205.9 CAR24976.1 - 0.00012 22.3 31.3 0.01 16.0 17.9 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein ATG16 PF08614.11 CAR24976.1 - 0.00014 22.1 38.2 0.0039 17.4 15.9 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) GAS PF13851.6 CAR24976.1 - 0.00017 21.0 38.9 0.1 11.9 38.7 2.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CAR24976.1 - 0.00038 20.4 46.2 0.021 14.8 20.2 3.3 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding Taxilin PF09728.9 CAR24976.1 - 0.00076 18.8 40.1 0.0018 17.6 16.3 2.8 1 1 2 3 3 3 2 Myosin-like coiled-coil protein BLOC1_2 PF10046.9 CAR24976.1 - 0.0028 17.9 28.9 0.6 10.4 10.4 3.8 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 CAR24976.1 - 0.0028 17.3 32.4 0.014 15.0 12.0 2.0 1 1 1 2 2 2 2 Intermediate filament protein Jnk-SapK_ap_N PF09744.9 CAR24976.1 - 0.0034 17.6 25.0 0.0034 17.6 25.0 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 DUF3450 PF11932.8 CAR24976.1 - 0.0034 16.7 32.4 0.016 14.5 15.1 2.3 1 1 2 3 3 3 1 Protein of unknown function (DUF3450) ADIP PF11559.8 CAR24976.1 - 0.0044 17.1 34.8 0.26 11.4 13.9 2.6 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding TelA PF05816.11 CAR24976.1 - 0.0082 15.2 3.1 0.0082 15.2 3.1 2.2 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) DUF4200 PF13863.6 CAR24976.1 - 0.0087 16.5 40.4 0.22 11.9 18.3 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) DUF1664 PF07889.12 CAR24976.1 - 0.012 15.6 20.1 0.09 12.8 5.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF5595 PF18077.1 CAR24976.1 - 0.013 15.6 7.7 0.013 15.6 7.7 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF5595) MbeD_MobD PF04899.12 CAR24976.1 - 0.015 15.4 13.9 0.033 14.3 3.0 2.9 2 1 1 3 3 3 0 MbeD/MobD like KASH_CCD PF14662.6 CAR24976.1 - 0.016 15.1 40.0 0.47 10.3 22.6 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 CAR24976.1 - 0.016 15.0 35.7 0.024 14.4 35.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) HOOK PF05622.12 CAR24976.1 - 0.016 13.4 35.2 0.02 13.1 35.2 1.0 1 0 0 1 1 1 0 HOOK protein WXG100 PF06013.12 CAR24976.1 - 0.016 15.4 16.4 1.9 8.7 0.2 3.8 2 1 1 3 3 3 0 Proteins of 100 residues with WXG ERM PF00769.19 CAR24976.1 - 0.017 14.9 40.3 0.059 13.2 17.0 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Cep57_CLD_2 PF14197.6 CAR24976.1 - 0.018 15.1 12.9 0.018 15.1 12.9 3.8 1 1 1 2 2 1 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 CAR24976.1 - 0.02 14.6 10.7 0.02 14.6 10.7 4.3 1 1 3 4 4 4 0 Septum formation initiator KELK PF15796.5 CAR24976.1 - 0.024 15.1 4.2 0.024 15.1 4.2 3.7 1 1 3 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Fez1 PF06818.15 CAR24976.1 - 0.026 15.0 34.1 0.051 14.0 33.8 1.6 1 1 0 1 1 1 0 Fez1 TPR_MLP1_2 PF07926.12 CAR24976.1 - 0.026 14.6 43.6 3 7.9 31.0 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ApoLp-III PF07464.11 CAR24976.1 - 0.032 14.3 4.6 0.032 14.3 4.6 3.0 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Atg14 PF10186.9 CAR24976.1 - 0.033 13.3 30.6 0.25 10.4 11.1 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uso1_p115_C PF04871.13 CAR24976.1 - 0.033 14.6 42.8 0.17 12.2 17.2 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 CAR24976.1 - 0.04 14.4 48.2 0.19 12.3 33.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region IFP_35_N PF07334.13 CAR24976.1 - 0.044 13.9 3.7 0.044 13.9 3.7 3.7 2 2 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FlaC_arch PF05377.11 CAR24976.1 - 0.046 14.1 29.9 0.71 10.3 3.1 4.4 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) IFT57 PF10498.9 CAR24976.1 - 0.058 12.3 32.2 0.7 8.8 32.2 2.2 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 bZIP_2 PF07716.15 CAR24976.1 - 0.06 13.4 4.9 0.06 13.4 4.9 4.8 3 2 1 4 4 4 0 Basic region leucine zipper Laminin_I PF06008.14 CAR24976.1 - 0.069 12.8 28.4 0.12 12.1 8.0 2.2 1 1 1 2 2 2 0 Laminin Domain I Sec34 PF04136.15 CAR24976.1 - 0.094 12.6 23.8 1.2 9.0 15.4 2.1 1 1 1 2 2 2 0 Sec34-like family Mod_r PF07200.13 CAR24976.1 - 0.096 12.8 38.6 0.46 10.6 17.1 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CLZ PF16526.5 CAR24976.1 - 0.098 13.0 31.5 0.18 12.1 2.5 3.8 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 CAR24976.1 - 0.11 12.6 37.9 1.1 9.5 1.5 4.5 1 1 1 2 2 1 0 bZIP transcription factor HMMR_C PF15908.5 CAR24976.1 - 0.13 12.5 27.1 0.21 11.9 3.0 3.7 1 1 1 2 2 1 0 Hyaluronan mediated motility receptor C-terminal Sec2p PF06428.11 CAR24976.1 - 0.15 12.0 38.2 0.5 10.4 17.8 3.8 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.12 CAR24976.1 - 0.15 12.5 13.9 2.7 8.5 0.2 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3552 PF12072.8 CAR24976.1 - 0.19 11.2 37.9 0.85 9.0 4.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DHR10 PF18595.1 CAR24976.1 - 0.19 11.8 39.7 1 9.5 18.1 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Nup54 PF13874.6 CAR24976.1 - 0.19 11.8 22.8 0.31 11.1 8.4 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Lebercilin PF15619.6 CAR24976.1 - 0.21 11.3 38.3 1.4 8.6 24.5 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF724 PF05266.14 CAR24976.1 - 0.22 11.3 31.9 0.15 11.8 10.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) APG17 PF04108.12 CAR24976.1 - 0.23 10.5 23.5 0.56 9.3 4.9 2.9 1 1 2 3 3 3 0 Autophagy protein Apg17 EzrA PF06160.12 CAR24976.1 - 0.24 9.5 34.4 0.64 8.1 33.5 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Nmad5 PF18757.1 CAR24976.1 - 0.32 11.2 19.7 9 6.4 19.7 2.3 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 ZapB PF06005.12 CAR24976.1 - 0.33 11.4 47.2 25 5.4 3.5 4.0 1 1 1 2 2 1 0 Cell division protein ZapB PI3K_P85_iSH2 PF16454.5 CAR24976.1 - 0.42 10.2 33.9 0.36 10.4 10.5 3.1 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3365 PF11845.8 CAR24976.1 - 0.44 10.9 4.7 0.67 10.3 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) DUF4795 PF16043.5 CAR24976.1 - 0.44 10.1 32.2 0.6 9.7 32.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Cortex-I_coil PF09304.10 CAR24976.1 - 0.46 10.7 30.4 0.15 12.3 2.1 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF4407 PF14362.6 CAR24976.1 - 0.48 9.7 23.6 0.81 9.0 23.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 CAR24976.1 - 0.52 10.2 40.2 0.38 10.7 3.6 3.2 1 1 2 3 3 3 0 Axonemal dynein light chain DUF2203 PF09969.9 CAR24976.1 - 0.53 11.0 22.9 0.13 13.0 8.9 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 CAR24976.1 - 0.55 10.4 24.8 1.3 9.2 13.6 2.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 CAR24976.1 - 0.6 7.6 31.7 0.86 7.0 31.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) T3SSipB PF16535.5 CAR24976.1 - 0.63 10.5 19.6 21 5.6 8.5 2.7 1 1 1 2 2 2 0 Type III cell invasion protein SipB Seryl_tRNA_N PF02403.22 CAR24976.1 - 0.63 10.3 33.2 1.1 9.5 1.6 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Spc24 PF08286.11 CAR24976.1 - 0.7 10.2 38.5 0.78 10.0 1.1 4.0 1 1 1 3 3 2 0 Spc24 subunit of Ndc80 HrpB7 PF09486.10 CAR24976.1 - 0.72 10.2 17.7 33 4.8 17.2 2.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) FapA PF03961.13 CAR24976.1 - 0.73 8.4 33.2 0.35 9.4 15.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 CAR24976.1 - 0.82 9.9 36.3 3.7 7.8 2.5 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding SHE3 PF17078.5 CAR24976.1 - 0.98 9.1 35.4 1.5 8.5 13.2 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4686 PF15742.5 CAR24976.1 - 1.2 8.2 40.0 6.8 5.7 40.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) TMPIT PF07851.13 CAR24976.1 - 1.4 8.1 29.6 0.92 8.7 11.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein CREPT PF16566.5 CAR24976.1 - 1.7 8.8 27.1 9.4 6.4 12.9 3.1 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Fzo_mitofusin PF04799.13 CAR24976.1 - 1.7 8.2 21.4 0.47 10.0 4.3 2.7 1 1 1 2 2 2 0 fzo-like conserved region YabA PF06156.13 CAR24976.1 - 1.8 9.2 30.5 1.8e+04 -5.3 30.5 3.1 1 1 0 1 1 0 0 Initiation control protein YabA AAA_13 PF13166.6 CAR24976.1 - 1.8 7.1 30.4 1.1 7.8 11.5 1.9 1 1 1 2 2 2 0 AAA domain FemAB PF02388.16 CAR24976.1 - 1.9 7.3 28.2 0.97 8.2 8.1 2.0 1 1 1 2 2 2 0 FemAB family Cnn_1N PF07989.11 CAR24976.1 - 2 8.6 38.6 8.3 6.6 7.3 3.8 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 FliD_C PF07195.12 CAR24976.1 - 2 7.8 23.7 0.74 9.2 0.4 3.1 1 1 1 2 2 1 0 Flagellar hook-associated protein 2 C-terminus FTA4 PF13093.6 CAR24976.1 - 2.1 8.2 25.5 1 9.2 14.2 2.4 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Wtap PF17098.5 CAR24976.1 - 2.2 8.2 32.0 0.11 12.4 23.7 2.1 2 0 0 2 2 2 0 WTAP/Mum2p family GrpE PF01025.19 CAR24976.1 - 2.5 7.7 39.7 0.71 9.5 4.5 3.8 1 1 2 3 3 3 0 GrpE Swi5 PF07061.11 CAR24976.1 - 2.6 8.2 35.4 6.8 6.9 5.3 4.1 1 1 3 4 4 4 0 Swi5 DUF745 PF05335.13 CAR24976.1 - 2.9 7.6 20.4 0.83 9.3 3.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF745) HisKA_3 PF07730.13 CAR24976.1 - 3 8.4 9.4 20 5.8 0.5 3.7 1 1 2 3 3 3 0 Histidine kinase OmpH PF03938.14 CAR24976.1 - 3.1 8.1 37.3 1.7 9.0 14.9 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) IZUMO PF15005.6 CAR24976.1 - 3.4 8.2 17.5 8.7 6.8 8.7 2.3 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated XhlA PF10779.9 CAR24976.1 - 3.4 7.9 32.0 1.9 8.8 2.7 4.1 1 1 2 4 4 4 0 Haemolysin XhlA CENP-K PF11802.8 CAR24976.1 - 3.9 7.0 34.4 12 5.4 18.0 1.9 1 1 0 1 1 1 0 Centromere-associated protein K FH2 PF02181.23 CAR24976.1 - 3.9 6.5 23.8 4.7 6.2 17.7 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain UPF0242 PF06785.11 CAR24976.1 - 4.3 7.4 42.4 1.8 8.6 19.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 CAR24976.1 - 4.4 7.3 38.2 2 8.4 29.5 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion GCN5L1 PF06320.13 CAR24976.1 - 4.8 7.4 24.2 2.7 8.2 14.9 2.7 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) Rho_Binding PF08912.11 CAR24976.1 - 4.9 8.1 46.2 2 9.3 2.8 3.9 1 1 3 4 4 4 0 Rho Binding DUF812 PF05667.11 CAR24976.1 - 5.1 5.9 38.2 19 3.9 38.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF3287 PF11690.8 CAR24976.1 - 5.4 6.8 10.2 11 5.8 2.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) CENP-H PF05837.12 CAR24976.1 - 5.9 7.3 33.4 3.8 8.0 14.4 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) KfrA_N PF11740.8 CAR24976.1 - 6.3 7.5 24.7 3 8.5 1.8 3.2 1 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term DUF5082 PF16888.5 CAR24976.1 - 6.3 7.1 27.8 18 5.6 6.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) CEP209_CC5 PF16574.5 CAR24976.1 - 6.5 6.9 36.0 0.57 10.4 14.9 2.5 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 DUF948 PF06103.11 CAR24976.1 - 6.9 7.0 14.5 9 6.6 4.1 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HalX PF08663.10 CAR24976.1 - 7.1 7.0 32.0 2.2 8.6 4.7 4.3 2 2 2 4 4 4 0 HalX domain FPP PF05911.11 CAR24976.1 - 7.4 4.6 38.1 5.5 5.0 17.5 1.9 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil HemX PF04375.14 CAR24976.1 - 7.4 5.7 27.9 4.6 6.4 14.1 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase ABC_tran_CTD PF16326.5 CAR24976.1 - 7.8 6.8 38.3 3 8.2 9.8 3.7 1 1 4 5 5 5 0 ABC transporter C-terminal domain FUSC PF04632.12 CAR24976.1 - 8.5 4.8 4.8 9.5 4.6 4.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lectin_N PF03954.14 CAR24976.1 - 9.2 6.0 20.4 15 5.4 8.4 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain THOC7 PF05615.13 CAR24976.1 - 9.3 6.5 31.5 5.2 7.4 13.0 2.7 1 1 1 2 2 2 0 Tho complex subunit 7 TRAF_BIRC3_bd PF16673.5 CAR24976.1 - 9.7 6.1 19.0 6.8 6.6 4.1 3.0 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DnaJ_C PF01556.18 CAR24977.1 - 8.8e-30 103.7 0.0 1.3e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR24977.1 - 9.2e-24 83.3 1.6 1.6e-23 82.6 1.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR24977.1 - 3.1e-12 46.7 18.5 5.9e-12 45.8 18.5 1.5 1 0 0 1 1 1 1 DnaJ central domain pP_pnuc_1 PF18165.1 CAR24977.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease FYVE PF01363.21 CAR24977.1 - 0.74 10.0 6.6 0.66 10.1 0.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger HypA PF01155.19 CAR24977.1 - 3.3 7.8 9.4 4.2 7.4 1.5 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RseC_MucC PF04246.12 CAR24977.1 - 8.1 6.4 12.4 2.3 8.2 4.3 2.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Peptidase_M1 PF01433.20 CAR24978.1 - 5e-51 173.4 0.0 7.9e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CAR24978.1 - 2e-36 126.2 0.0 2.9e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CAR24978.1 - 5.3e-23 82.2 0.1 1.3e-22 80.9 0.1 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SDP_N PF12278.8 CAR24979.1 - 7.7 6.7 10.9 0.41 10.8 5.2 1.9 2 0 0 2 2 2 0 Sex determination protein N terminal Apolipoprotein PF01442.18 CAR24980.1 - 9e-06 25.7 45.2 0.0017 18.2 7.8 4.1 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 CAR24980.1 - 0.0016 18.5 14.2 0.034 14.2 0.5 4.0 3 1 0 3 3 3 3 Protein of unknown function (DUF1664) Phi-29_GP4 PF05464.11 CAR24980.1 - 0.038 14.3 0.2 0.076 13.3 0.2 1.5 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Exonuc_VII_L PF02601.15 CAR24980.1 - 0.65 9.5 28.3 2.8 7.4 6.2 3.2 1 1 2 3 3 3 0 Exonuclease VII, large subunit YtxH PF12732.7 CAR24980.1 - 0.72 10.4 57.7 0.21 12.1 4.7 7.9 2 2 2 6 6 6 0 YtxH-like protein ApoLp-III PF07464.11 CAR24980.1 - 0.99 9.5 31.3 3.8 7.6 4.2 5.2 3 1 2 5 5 5 0 Apolipophorin-III precursor (apoLp-III) CwsA PF10814.8 CAR24980.1 - 6 7.0 9.2 5 7.3 0.2 3.9 2 1 2 4 4 4 0 Cell wall synthesis protein CwsA KxDL PF10241.9 CAR24980.1 - 7.9 6.8 16.4 8.6 6.7 3.7 4.4 3 2 1 4 4 4 0 Uncharacterized conserved protein DUF1752 PF08550.10 CAR24981.1 - 2.7e-09 36.7 0.4 5.1e-09 35.8 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.18 CAR24982.1 - 1.6e-31 109.9 0.1 2.2e-31 109.5 0.1 1.1 1 0 0 1 1 1 1 Brix domain Kri1 PF05178.12 CAR24982.1 - 0.032 14.8 1.2 0.048 14.2 1.2 1.2 1 0 0 1 1 1 0 KRI1-like family tRNA-synt_2 PF00152.20 CAR24984.1 - 2.6e-63 214.0 0.0 3.1e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CAR24984.1 - 7.3e-07 28.9 0.2 0.00012 21.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CAR24984.1 - 1.7e-05 24.7 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_HII PF01351.18 CAR24985.1 - 4.3e-61 206.2 0.0 5.5e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Vmethyltransf PF01660.17 CAR24985.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Viral methyltransferase 2-oxoacid_dh PF00198.23 CAR24986.1 - 8.9e-74 247.8 0.1 1.1e-73 247.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CAR24986.1 - 3.7e-16 59.2 0.0 1.1e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 CAR24986.1 - 4.2e-16 58.5 0.1 8.5e-16 57.5 0.1 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3614 PF12267.8 CAR24986.1 - 0.23 11.9 1.1 1.4 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Mito_carr PF00153.27 CAR24987.1 - 1.1e-63 211.1 3.7 1.2e-22 79.6 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.18 CAR24988.1 - 1.4e-11 44.7 0.9 1e-09 38.7 0.1 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 CSM2 PF16834.5 CAR24989.1 - 2.6e-60 203.5 0.0 3e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Shu complex component Csm2, DNA-binding Forkhead PF00250.18 CAR24990.1 - 6.2e-34 116.1 0.4 1.6e-33 114.8 0.4 1.8 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CAR24990.1 - 4.3e-11 43.0 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 CAR24990.1 - 0.0018 18.6 0.1 0.0049 17.2 0.1 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family DUF4746 PF15928.5 CAR24990.1 - 1.7 8.0 16.0 2.7 7.3 16.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GREB1 PF15782.5 CAR24990.1 - 2.1 5.3 24.7 2.6 5.1 24.7 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RR_TM4-6 PF06459.12 CAR24990.1 - 3.7 7.3 24.0 7.6 6.3 24.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fungal_trans PF04082.18 CAR24991.1 - 1e-37 129.7 0.4 1.7e-37 128.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR24991.1 - 9.2e-12 44.9 10.8 1.5e-11 44.2 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MOR2-PAG1_N PF14222.6 CAR24992.1 - 1.7e-181 604.9 9.3 1.7e-181 604.9 9.3 1.7 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CAR24992.1 - 5.2e-87 291.9 3.6 1.5e-86 290.4 0.9 2.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CAR24992.1 - 2.5e-23 81.8 8.5 3.3e-11 41.6 0.3 3.6 1 1 2 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 CAR24992.1 - 0.00012 22.1 4.7 0.00019 21.5 0.1 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DnaB_bind PF10410.9 CAR24992.1 - 0.089 13.0 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase MMS19_C PF12460.8 CAR24993.1 - 3.2e-87 293.4 15.9 3.2e-87 293.4 15.9 3.1 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CAR24993.1 - 5.5e-83 278.5 5.2 6.1e-81 271.8 0.3 3.3 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 CAR24993.1 - 0.0012 19.0 7.9 0.047 13.9 0.2 4.4 3 2 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CAR24993.1 - 0.0036 17.8 0.2 7.3 7.2 0.0 3.6 4 0 0 4 4 4 2 HEAT-like repeat Ipi1_N PF12333.8 CAR24993.1 - 0.073 13.7 1.2 0.66 10.6 0.0 3.1 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation ParcG PF10274.9 CAR24993.1 - 0.2 11.7 3.0 0.59 10.2 0.4 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein RRT14 PF17075.5 CAR24994.1 - 3.8e-62 209.9 17.1 4.5e-62 209.7 17.1 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 SOBP PF15279.6 CAR24994.1 - 3.3 8.2 6.2 4.4 7.8 6.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4065 PF13274.6 CAR24994.1 - 3.9 8.4 5.7 2.3 9.1 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) SNF2_N PF00176.23 CAR24995.1 - 4.7e-76 255.8 0.2 1.2e-75 254.5 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR24995.1 - 3.7e-21 75.5 0.2 1.1e-18 67.6 0.0 3.9 4 1 0 4 4 4 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CAR24995.1 - 1.6e-17 63.4 0.0 3.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 CAR24995.1 - 2.2e-11 44.1 0.9 7.2e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 CAR24995.1 - 3.9e-10 39.9 4.4 3.9e-10 39.9 4.4 2.7 3 0 0 3 3 3 1 HSA SnAC PF14619.6 CAR24995.1 - 2.4e-09 37.7 0.1 2.4e-09 37.7 0.1 4.1 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Beta-lactamase2 PF13354.6 CAR24995.1 - 0.13 11.9 0.7 0.36 10.4 0.1 2.0 2 0 0 2 2 2 0 Beta-lactamase enzyme family Ribosomal_L6 PF00347.23 CAR24996.1 - 5.7e-32 110.2 11.1 1e-16 61.4 4.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 SLS PF14611.6 CAR24996.1 - 0.032 14.1 0.2 0.043 13.6 0.2 1.4 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator Transket_pyr PF02779.24 CAR24998.1 - 7.3e-65 218.0 0.0 1.2e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CAR24998.1 - 1.6e-56 191.5 0.0 2.4e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CAR24998.1 - 2.9e-47 160.2 0.0 4.6e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CAR24998.1 - 1.2e-20 72.8 0.8 1.2e-20 72.8 0.8 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Imm52 PF15579.6 CAR24998.1 - 0.026 14.4 0.2 1 9.2 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 52 adh_short PF00106.25 CAR24999.1 - 2.2e-47 161.0 0.0 2.8e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR24999.1 - 1.5e-33 116.3 0.0 1.9e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR24999.1 - 4.3e-08 33.3 0.0 8.1e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CAR24999.1 - 4e-05 23.1 0.0 0.00023 20.6 0.0 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CAR24999.1 - 0.00012 21.6 0.0 0.00027 20.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CAR24999.1 - 0.00023 21.1 0.0 0.00049 20.0 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CAR24999.1 - 0.00036 19.7 0.0 0.0005 19.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CAR24999.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SUN PF03856.13 CAR25000.1 - 5.9e-98 327.2 13.3 8.3e-98 326.7 13.3 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Apt1 PF10351.9 CAR25000.1 - 0.017 14.0 15.0 0.023 13.6 15.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CAR25000.1 - 2.8 6.6 9.2 3.8 6.2 9.2 1.1 1 0 0 1 1 1 0 Presenilin SPX PF03105.19 CAR25000.1 - 7.7 6.3 26.9 10 5.9 26.9 1.1 1 0 0 1 1 1 0 SPX domain MFS_1 PF07690.16 CAR25001.1 - 1.7e-42 145.6 23.5 1.6e-35 122.7 15.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR25001.1 - 8.7e-07 28.2 30.7 4.9e-06 25.7 15.5 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 CAR25002.1 - 4e-42 144.4 21.7 4e-42 144.4 21.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR25002.1 - 2.5e-11 43.1 11.6 2.5e-11 43.1 11.6 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter LapA_dom PF06305.11 CAR25002.1 - 0.019 14.7 0.1 0.62 9.9 0.0 3.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain OATP PF03137.20 CAR25002.1 - 1.3 7.2 17.8 0.12 10.6 0.1 3.3 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Gly-zipper_Omp PF13488.6 CAR25002.1 - 9.4 6.3 8.0 8.2 6.5 3.6 2.6 2 1 0 2 2 2 0 Glycine zipper DnaJ_C PF01556.18 CAR25003.1 - 1.7e-41 141.8 0.2 2.2e-41 141.4 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR25003.1 - 1.4e-23 82.8 1.0 2.4e-23 82.0 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR25003.1 - 3.3e-16 59.4 17.6 6e-16 58.6 17.6 1.5 1 0 0 1 1 1 1 DnaJ central domain Coatomer_WDAD PF04053.14 CAR25003.1 - 3.4e-05 23.1 0.0 5.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region MCM_OB PF17207.3 CAR25003.1 - 0.075 12.9 1.5 0.098 12.5 0.8 1.6 1 1 0 1 1 1 0 MCM OB domain Anti-TRAP PF15777.5 CAR25003.1 - 0.098 12.6 16.4 0.16 12.0 3.2 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CAR25003.1 - 0.36 10.9 10.8 2.7 8.1 1.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MTS PF05175.14 CAR25004.1 - 1.4e-12 47.5 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CAR25004.1 - 1.1e-06 29.3 0.0 2.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR25004.1 - 2.3e-06 27.5 0.0 3.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR25004.1 - 0.034 14.8 0.0 0.075 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 CAR25004.1 - 0.047 13.0 0.0 0.063 12.5 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase PrmA PF06325.13 CAR25004.1 - 0.048 13.1 0.0 0.068 12.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 CAR25004.1 - 0.073 13.7 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 PrmC N-terminal domain UPF0020 PF01170.18 CAR25004.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Gcd10p PF04189.13 CAR25005.1 - 2e-103 345.7 0.1 2.4e-103 345.4 0.1 1.1 1 0 0 1 1 1 1 Gcd10p family Mrr_N PF14338.6 CAR25005.1 - 0.015 15.4 0.8 0.061 13.5 0.1 2.1 2 0 0 2 2 2 0 Mrr N-terminal domain CNP_C_terminal PF17839.1 CAR25005.1 - 0.27 12.0 0.1 0.27 12.0 0.1 2.3 2 1 0 2 2 2 0 C-terminal domain of cyclic nucleotide phosphodiesterase Methyltr_RsmB-F PF01189.17 CAR25006.1 - 2.1e-81 272.4 0.0 4.2e-81 271.4 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CAR25006.1 - 9.5e-09 35.6 0.0 3.9e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CAR25006.1 - 0.0097 16.0 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Actin PF00022.19 CAR25007.1 - 5.3e-50 170.2 0.0 2.2e-31 108.9 0.0 2.6 2 2 0 2 2 2 2 Actin MFS_1 PF07690.16 CAR25008.1 - 1.5e-08 34.0 11.8 1.5e-08 34.0 11.8 3.6 2 1 1 4 4 4 3 Major Facilitator Superfamily FAS_I_H PF18314.1 CAR25009.1 - 9.3e-29 100.5 0.0 2e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 CAR25009.1 - 1.2e-22 81.0 0.4 1.1e-21 77.8 0.0 2.4 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 CAR25009.1 - 1.1e-21 77.6 0.7 2e-21 76.7 0.7 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CAR25009.1 - 5.1e-13 49.1 0.0 1.6e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CAR25009.1 - 0.095 12.0 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ras PF00071.22 CAR25010.1 - 5.1e-56 188.7 0.0 6.7e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR25010.1 - 1.6e-22 80.0 0.0 2.7e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR25010.1 - 4e-10 39.4 0.0 6.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAR25010.1 - 0.0011 18.2 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 CAR25010.1 - 0.0025 17.3 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CAR25010.1 - 0.0059 16.0 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR25010.1 - 0.0083 16.2 0.0 0.021 14.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CAR25010.1 - 0.059 13.9 0.1 0.11 13.0 0.1 1.7 1 1 0 1 1 1 0 ABC transporter DLIC PF05783.11 CAR25010.1 - 0.087 11.6 0.2 0.15 10.8 0.2 1.6 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) Insulin_TMD PF17870.1 CAR25011.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment ABC2_membrane_3 PF12698.7 CAR25011.1 - 0.22 10.6 2.8 0.19 10.8 0.2 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein Y_phosphatase2 PF03162.13 CAR25012.1 - 7.8e-54 181.7 0.0 8.4e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR25012.1 - 6.6e-07 29.5 0.0 7.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Arginase PF00491.21 CAR25012.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Arginase family Aminotran_1_2 PF00155.21 CAR25013.1 - 6.6e-61 206.5 0.0 7.6e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CAR25013.1 - 0.00078 18.1 0.1 0.0019 16.8 0.1 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 CAR25013.1 - 0.0098 14.8 0.0 0.022 13.7 0.0 1.5 1 1 0 1 1 1 1 Allinase NUP214 PF16755.5 CAR25014.1 - 1.6e-96 323.7 3.8 2.8e-96 322.9 3.8 1.4 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Keratin_B2_2 PF13885.6 CAR25014.1 - 0.0049 16.8 0.0 0.73 9.8 0.0 3.2 1 1 1 2 2 2 1 Keratin, high sulfur B2 protein CODH_A_N PF18537.1 CAR25014.1 - 0.027 14.5 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain Porin_3 PF01459.22 CAR25015.1 - 1.5e-73 247.6 0.5 1.7e-73 247.4 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Vac7 PF12751.7 CAR25016.1 - 4.6e-24 85.6 17.3 3.5e-14 53.0 4.3 3.6 2 1 1 3 3 3 2 Vacuolar segregation subunit 7 DSPc PF00782.20 CAR25017.1 - 4.7e-37 126.8 0.6 7.6e-37 126.1 0.6 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR25017.1 - 4.2e-05 23.2 0.0 7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CAR25017.1 - 0.031 14.6 0.5 0.075 13.3 0.3 1.7 1 1 0 1 1 1 0 Rit1 DUSP-like domain LIX1 PF14954.6 CAR25017.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Limb expression 1 PTPlike_phytase PF14566.6 CAR25017.1 - 0.084 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Ank_2 PF12796.7 CAR25018.1 - 4.2e-29 101.0 0.2 5.1e-13 49.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR25018.1 - 6.5e-26 90.4 0.2 6e-11 42.6 0.1 4.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR25018.1 - 3.1e-24 84.7 1.0 4.8e-08 33.1 0.2 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CAR25018.1 - 1.6e-23 82.1 5.7 1.6e-07 31.4 0.6 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CAR25018.1 - 7.4e-23 78.2 0.1 1.6e-07 31.1 0.2 6.4 6 0 0 6 6 6 4 Ankyrin repeat COX4 PF02936.14 CAR25019.1 - 3.4e-34 117.8 0.2 4e-34 117.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 CAR25019.1 - 0.016 15.7 2.1 0.016 15.7 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) N1221 PF07923.13 CAR25019.1 - 0.064 12.4 0.2 0.09 11.9 0.2 1.3 1 1 0 1 1 1 0 N1221-like protein DUF1289 PF06945.13 CAR25019.1 - 0.81 9.5 2.0 8.6 6.3 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Methyltransf_12 PF08242.12 CAR25020.1 - 0.15 12.9 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain COG5 PF10392.9 CAR25021.1 - 3.6e-32 111.3 3.4 3.6e-32 111.3 3.4 3.1 3 1 1 4 4 4 1 Golgi transport complex subunit 5 DUF2011 PF09428.10 CAR25022.1 - 4e-21 75.0 0.4 7.5e-21 74.2 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Sec23_trunk PF04811.15 CAR25023.1 - 2.4e-70 236.9 0.0 5e-70 235.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CAR25023.1 - 2.1e-19 69.3 0.1 4.9e-19 68.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CAR25023.1 - 1.3e-17 63.5 3.8 2.6e-17 62.6 3.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CAR25023.1 - 3.2e-16 59.8 1.2 1.3e-15 57.9 0.0 2.6 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CAR25023.1 - 3.3e-09 36.5 0.0 7.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CAR25023.1 - 0.067 12.6 0.3 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Metallopep PF12044.8 CAR25024.1 - 1.1e-168 561.4 0.0 1.3e-168 561.1 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CAR25024.1 - 5.5e-05 23.1 0.8 0.00032 20.6 0.4 2.1 1 1 1 2 2 2 1 Jacalin-like lectin domain Reprolysin_3 PF13582.6 CAR25024.1 - 0.024 15.1 0.0 0.05 14.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CAR25024.1 - 0.027 14.6 0.1 0.046 13.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CAR25024.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Matrixin 6PF2K PF01591.18 CAR25025.1 - 5.4e-83 277.7 0.3 8e-83 277.1 0.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CAR25025.1 - 5.7e-33 114.2 0.0 2e-31 109.2 0.0 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CAR25025.1 - 2.1e-06 27.9 0.0 6.3e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR25025.1 - 0.0003 21.3 0.0 0.0008 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CAR25025.1 - 0.0093 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 CAR25025.1 - 0.017 15.6 0.0 0.053 13.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CAR25025.1 - 0.045 13.7 0.0 0.086 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.14 CAR25025.1 - 0.16 12.0 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mob1_phocein PF03637.17 CAR25026.1 - 1.2e-68 230.5 0.3 1.5e-68 230.1 0.3 1.2 1 0 0 1 1 1 1 Mob1/phocein family ALG11_N PF15924.5 CAR25027.1 - 4.3e-80 268.7 0.5 8.1e-80 267.8 0.5 1.5 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CAR25027.1 - 8.2e-14 51.5 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAR25027.1 - 0.0002 21.8 0.0 0.00049 20.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 PH PF00169.29 CAR25028.1 - 8.8e-12 45.5 0.5 1.7e-11 44.5 0.5 1.5 1 0 0 1 1 1 1 PH domain PI3K_P85_iSH2 PF16454.5 CAR25028.1 - 0.085 12.5 0.9 0.3 10.7 0.0 2.1 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain PRA1 PF03208.19 CAR25030.1 - 1.9e-38 131.3 3.0 2.3e-38 131.1 3.0 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 CAR25030.1 - 0.11 11.3 0.7 0.11 11.2 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2722 PF10846.8 CAR25031.1 - 5.9e-52 177.2 17.3 6.7e-45 153.9 6.5 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2722) SHQ1 PF04925.15 CAR25032.1 - 3.1e-71 238.6 1.5 4.6e-71 238.0 1.5 1.3 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.17 CAR25033.1 - 8.4e-115 383.4 0.0 1e-114 383.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.11 CAR25034.1 - 8.3e-142 473.6 20.7 8.3e-142 473.6 20.7 1.3 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Pro_CA PF00484.19 CAR25036.1 - 1.1e-40 139.5 0.4 1.4e-40 139.2 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PRAP PF15314.6 CAR25036.1 - 0.01 16.3 0.3 0.019 15.4 0.3 1.5 1 0 0 1 1 1 1 Proline-rich acidic protein 1, pregnancy-specific uterine Glyco_hydro_15 PF00723.21 CAR25037.1 - 3.3e-55 187.7 0.0 4.8e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_LYR_2 PF13233.6 CAR25038.1 - 3e-15 56.7 8.8 8.8e-15 55.2 8.8 1.8 1 1 0 1 1 1 1 Complex1_LYR-like DUF3793 PF12672.7 CAR25038.1 - 0.2 11.7 2.4 0.27 11.3 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3793) Iso_dh PF00180.20 CAR25039.1 - 2.5e-79 267.0 0.0 2.8e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CLTH PF10607.9 CAR25040.1 - 2.2e-29 102.3 1.2 2.2e-29 102.3 1.2 2.5 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.15 CAR25040.1 - 0.013 15.6 0.0 0.051 13.8 0.0 2.0 1 0 0 1 1 1 0 U-box domain DUF2431 PF10354.9 CAR25041.1 - 4.2e-56 189.8 0.8 6.4e-56 189.2 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Band_3_cyto PF07565.13 CAR25041.1 - 0.31 10.8 3.2 0.14 11.9 0.3 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PIG-H PF10181.9 CAR25042.1 - 6.7e-22 77.1 0.3 1.1e-21 76.5 0.3 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-bind_7 PF15963.5 CAR25043.1 - 4.5e-27 93.8 0.1 4.5e-27 93.8 0.1 2.9 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CAR25043.1 - 9.1e-09 35.4 0.2 2.3e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR25043.1 - 0.036 14.3 0.4 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain PulA_N1 PF17999.1 CAR25043.1 - 0.17 12.6 1.0 4.9 8.0 0.1 2.8 2 1 0 2 2 2 0 Pullulanase N1-terminal domain WD40 PF00400.32 CAR25044.1 - 7.8e-11 42.4 0.7 9.6e-05 23.1 0.1 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25044.1 - 1.6e-05 25.1 0.5 0.39 11.0 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CAR25044.1 - 0.0066 15.2 0.0 0.14 10.9 0.0 2.3 2 1 0 2 2 2 1 Nup133 N terminal like Pkinase PF00069.25 CAR25045.1 - 2.4e-37 128.7 0.0 4.9e-37 127.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25045.1 - 5.5e-28 98.0 0.0 8.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR25045.1 - 0.013 14.8 0.0 0.028 13.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 CAR25045.1 - 0.045 13.7 0.0 1.7 8.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAR25045.1 - 1.8 7.4 8.1 3.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Haspin like kinase domain Arb2 PF09757.9 CAR25046.1 - 3.1e-91 305.1 0.0 4.5e-91 304.6 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 CAR25046.1 - 8.8e-89 298.0 0.0 1.5e-88 297.2 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Methyltr_RsmB-F PF01189.17 CAR25047.1 - 1.6e-19 70.3 0.1 4.2e-17 62.5 0.1 2.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MPP6 PF10175.9 CAR25047.1 - 0.00056 20.4 0.3 0.0021 18.6 0.2 2.0 2 0 0 2 2 2 1 M-phase phosphoprotein 6 Iso_dh PF00180.20 CAR25048.1 - 1.1e-108 363.4 0.0 1.4e-108 363.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pox_C4_C10 PF03336.13 CAR25048.1 - 0.024 13.8 0.2 0.034 13.3 0.2 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein R3H PF01424.22 CAR25049.1 - 4.1e-21 74.7 0.5 1.2e-20 73.2 0.1 2.1 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 CAR25049.1 - 6.3e-07 29.3 37.2 2.1e-06 27.6 13.9 12.3 11 0 0 11 11 11 4 NF-X1 type zinc finger CENP-B_dimeris PF09026.10 CAR25049.1 - 0.89 10.0 6.1 1.7 9.1 6.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Methyltransf_16 PF10294.9 CAR25050.1 - 3.5e-48 163.6 0.0 4.5e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 CAR25050.1 - 0.023 14.4 0.1 0.037 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CAR25050.1 - 0.076 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CAR25050.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MRP-S25 PF13741.6 CAR25051.1 - 1e-94 316.4 5.2 1.2e-94 316.2 5.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CAR25051.1 - 3.7e-06 27.2 2.9 0.0013 19.0 0.2 3.0 1 1 1 3 3 3 2 Mitochondrial ribosomal protein S23 DUF1242 PF06842.12 CAR25052.1 - 9.3e-17 60.5 0.4 1.2e-16 60.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) UTP25 PF06862.12 CAR25053.1 - 4.8e-198 658.7 8.2 6e-198 658.4 8.2 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 CAR25053.1 - 8.1e-05 22.5 0.3 0.49 10.1 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase POT1PC PF16686.5 CAR25053.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Helicase_C PF00271.31 CAR25053.1 - 0.083 13.2 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 Helicase conserved C-terminal domain ICE2 PF08426.10 CAR25054.1 - 9.4e-158 525.6 22.3 1.1e-157 525.4 22.3 1.0 1 0 0 1 1 1 1 ICE2 DUF3810 PF12725.7 CAR25054.1 - 1.5 8.1 7.0 0.21 10.9 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) Cyclin_N PF00134.23 CAR25055.1 - 4e-16 58.9 0.1 9.1e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CAR25055.1 - 5.4e-06 26.7 0.2 1.2e-05 25.6 0.2 1.6 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 CAR25055.1 - 0.00014 21.9 1.6 0.032 14.3 0.1 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain TRAM_LAG1_CLN8 PF03798.16 CAR25056.1 - 1.5e-43 148.9 27.7 3.1e-43 147.8 27.7 1.5 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 CAR25056.1 - 1.3e-15 56.8 0.4 1.3e-15 56.8 0.4 2.5 2 0 0 2 2 2 1 TRAM1-like protein Aa_trans PF01490.18 CAR25057.1 - 7.1e-106 354.3 19.9 8.2e-106 354.1 19.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Y_phosphatase2 PF03162.13 CAR25058.1 - 2.3e-64 215.9 0.0 3.3e-64 215.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR25058.1 - 1.3e-06 28.6 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CAR25058.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR25058.1 - 0.0037 16.9 0.0 0.0057 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Aim19 PF10315.9 CAR25059.1 - 4.7e-42 142.9 4.6 5.3e-42 142.7 4.6 1.0 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Histone PF00125.24 CAR25060.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CAR25060.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CAR25060.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CAR25060.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAR25060.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CAR25060.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CAR25061.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CAR25061.1 - 2.1e-05 24.9 0.1 2.5e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CAR25061.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CAR25061.1 - 3.6e-05 24.0 0.1 6.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CAR25061.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CAR25061.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAR25061.1 - 0.0067 16.4 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CAR25061.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.16 CAR25062.1 - 1.1e-85 287.7 8.6 6.7e-55 186.6 3.8 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase AA_permease_2 PF13520.6 CAR25063.1 - 7.7e-72 242.4 52.8 9.2e-72 242.2 52.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR25063.1 - 3.6e-15 55.5 44.6 5e-15 55.1 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease Sds3 PF08598.11 CAR25064.1 - 5.6e-73 245.5 12.6 7.3e-73 245.2 12.6 1.1 1 0 0 1 1 1 1 Sds3-like DASH_Dad3 PF08656.10 CAR25064.1 - 0.23 11.5 3.2 0.71 10.0 0.4 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 STAT_int PF02865.17 CAR25064.1 - 1.3 9.5 5.1 3.6 8.0 0.6 2.3 2 0 0 2 2 2 0 STAT protein, protein interaction domain Met_10 PF02475.16 CAR25065.1 - 3.8e-10 39.9 0.0 5.9e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 CAR25065.1 - 0.0061 16.2 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 CAR25065.1 - 0.087 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain zf-H2C2_2 PF13465.6 CAR25066.1 - 5.7e-14 51.8 10.2 1.5e-06 28.4 0.2 3.8 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CAR25066.1 - 2.2e-13 49.9 11.4 9.9e-07 28.9 1.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR25066.1 - 5.3e-09 36.2 8.8 0.00068 20.3 1.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR25066.1 - 2e-07 31.1 3.2 0.0014 18.8 0.3 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR25066.1 - 7.9e-07 29.3 2.2 4.6e-05 23.7 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CAR25066.1 - 2e-05 24.5 5.5 0.013 15.5 0.2 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 CAR25066.1 - 0.00065 20.2 2.5 0.00065 20.2 2.5 1.8 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 CAR25066.1 - 0.011 15.3 0.9 0.42 10.3 0.1 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CAR25066.1 - 0.054 13.3 0.9 18 5.2 0.0 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CAR25066.1 - 0.25 11.5 1.1 0.66 10.1 1.1 1.8 1 0 0 1 1 1 0 Zinc ribbon domain FYVE PF01363.21 CAR25066.1 - 0.29 11.3 4.8 0.52 10.5 4.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-BED PF02892.15 CAR25066.1 - 0.57 10.2 3.3 8.6 6.5 1.4 2.8 2 1 0 2 2 2 0 BED zinc finger C1_4 PF07975.12 CAR25066.1 - 2.6 8.3 4.3 49 4.3 0.6 2.5 1 1 0 2 2 2 0 TFIIH C1-like domain Bac_surface_Ag PF01103.23 CAR25067.1 - 4.6e-48 164.4 6.5 5.7e-48 164.1 6.5 1.1 1 0 0 1 1 1 1 Surface antigen DFP PF04127.15 CAR25068.1 - 8.1e-16 58.4 0.0 2.8e-06 27.3 0.0 2.9 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Na_H_Exchanger PF00999.21 CAR25069.1 - 2.4e-55 187.9 32.1 3.6e-55 187.3 32.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SCAMP PF04144.13 CAR25069.1 - 1.7 8.9 17.6 0.017 15.5 6.6 2.9 2 2 0 2 2 2 0 SCAMP family RRM_1 PF00076.22 CAR25070.1 - 2.3e-53 177.9 0.5 9.1e-19 67.1 0.2 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR25070.1 - 2.7e-09 36.8 0.0 5.7e-05 22.9 0.0 2.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CAR25070.1 - 3.9e-06 26.5 0.0 0.0019 17.8 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR25070.1 - 0.00022 21.3 0.6 0.83 9.8 0.0 4.0 3 1 1 4 4 4 1 RNA recognition motif PHM7_cyt PF14703.6 CAR25070.1 - 0.0019 18.5 0.6 0.84 9.8 0.2 2.6 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 CAR25070.1 - 0.022 14.8 0.4 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 CAR25070.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 RRM-like domain UCH PF00443.29 CAR25071.1 - 1.4e-45 155.8 0.3 1.9e-45 155.4 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR25071.1 - 3.8e-07 30.0 2.0 8.9e-06 25.5 2.0 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Frataxin_Cyay PF01491.16 CAR25073.1 - 3e-36 123.8 0.0 3.6e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Glyco_hydro_38N PF01074.22 CAR25074.1 - 3.6e-82 276.0 0.3 5.7e-82 275.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CAR25074.1 - 3.9e-53 180.7 0.1 6.6e-53 179.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CAR25074.1 - 3.7e-26 91.1 0.0 7.5e-26 90.1 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CAR25074.1 - 5.4e-10 39.2 0.3 4.6e-09 36.3 0.1 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Prenyltrans PF00432.21 CAR25075.1 - 2.7e-28 97.4 3.4 3.2e-08 33.2 0.0 5.0 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Mito_carr PF00153.27 CAR25076.1 - 1.7e-48 162.5 1.2 1.1e-18 66.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ACPS PF01648.20 CAR25077.1 - 2.1e-11 44.0 0.0 3.6e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Pex14_N PF04695.13 CAR25078.1 - 1.1e-27 97.7 2.2 1.1e-27 97.7 2.2 3.5 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TACC_C PF05010.14 CAR25078.1 - 0.00048 20.0 4.0 0.001 18.9 4.0 1.5 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 CAR25078.1 - 0.0028 17.7 0.5 0.0057 16.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) SLATT_6 PF18169.1 CAR25078.1 - 0.026 14.1 0.4 0.046 13.3 0.4 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 DUF2935 PF11155.8 CAR25078.1 - 0.037 14.3 0.3 0.098 13.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Syntaxin-6_N PF09177.11 CAR25078.1 - 0.038 14.5 5.0 0.044 14.3 3.7 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal zf-C4H2 PF10146.9 CAR25078.1 - 0.071 13.4 7.6 0.13 12.5 7.6 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein UPF0242 PF06785.11 CAR25078.1 - 0.33 11.0 11.8 0.74 9.9 11.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Nup54 PF13874.6 CAR25078.1 - 0.82 9.8 11.2 0.51 10.4 7.2 2.4 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 GTP-bdg_M PF16360.5 CAR25078.1 - 0.88 10.2 3.6 3.7 8.2 0.5 2.4 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Rootletin PF15035.6 CAR25078.1 - 1.2 9.1 10.4 1.5 8.8 9.2 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion TMPIT PF07851.13 CAR25078.1 - 2.2 7.5 5.0 3.9 6.6 5.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein DUF1043 PF06295.12 CAR25078.1 - 6.6 6.8 13.9 5.2 7.1 6.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Med5 PF08689.10 CAR25079.1 - 0 1338.8 34.7 0 1338.5 34.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.23 CAR25080.1 - 9.3e-66 221.9 0.9 9.3e-66 221.9 0.9 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 CAR25080.1 - 8.4e-49 165.4 20.9 8.4e-49 165.4 20.9 4.0 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 CAR25080.1 - 1.3e-17 64.1 0.1 7.5e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25080.1 - 3.9e-06 27.0 0.0 3.9e-06 27.0 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 CAR25080.1 - 0.0017 18.1 0.3 0.0049 16.6 0.3 1.8 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain TFIIA PF03153.13 CAR25080.1 - 6.5 6.6 55.0 0.032 14.2 32.9 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sugar_tr PF00083.24 CAR25081.1 - 4.9e-86 289.4 23.5 6.8e-86 288.9 23.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR25081.1 - 8.8e-32 110.4 25.2 8.8e-32 110.4 25.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.18 CAR25081.1 - 7.2e-06 25.0 0.3 1.5e-05 24.0 0.1 1.6 1 1 0 1 1 1 1 Reduced folate carrier TRI12 PF06609.13 CAR25081.1 - 0.00024 19.6 5.3 0.00024 19.6 5.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 CAR25083.1 - 2.4e-83 280.1 0.0 3e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR25083.1 - 9.7e-25 87.4 0.1 2.7e-24 86.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CAR25083.1 - 5.1e-21 74.4 0.1 1.2e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Mem_trans PF03547.18 CAR25084.1 - 2.7e-30 105.1 0.3 3.3e-29 101.5 0.3 2.0 1 1 0 1 1 1 1 Membrane transport protein NUDIX PF00293.28 CAR25085.1 - 4.2e-10 39.8 0.0 8.1e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Stm1_N PF09598.10 CAR25086.1 - 5.6e-09 36.7 8.1 5.6e-09 36.7 8.1 4.7 2 2 1 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.15 CAR25086.1 - 0.24 12.2 18.0 0.045 14.6 13.1 2.4 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family ARD PF03079.14 CAR25086.1 - 1.2 9.3 5.2 0.29 11.3 1.6 1.7 1 1 1 2 2 2 0 ARD/ARD' family Stb3 PF10330.9 CAR25087.1 - 8.7e-30 102.6 0.0 1.7e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF2415 PF10313.9 CAR25088.1 - 3.6e-22 78.0 0.2 4.2e-21 74.6 0.9 2.5 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) CDC37_N PF03234.14 CAR25089.1 - 1.1e-44 152.4 6.7 1.1e-44 152.4 6.7 3.5 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CAR25089.1 - 2.5e-39 133.8 4.5 7.4e-39 132.3 4.5 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CAR25089.1 - 5.7e-29 100.2 4.6 5.7e-29 100.2 4.6 2.5 3 0 0 3 3 3 1 Cdc37 C terminal domain TFIID_30kDa PF03540.13 CAR25090.1 - 3.7e-26 90.8 0.1 5.7e-26 90.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TPM_phosphatase PF04536.14 CAR25090.1 - 0.036 14.2 0.2 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 TPM domain Bromo_TP PF07524.13 CAR25090.1 - 0.046 13.7 0.1 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Bromodomain associated Pep3_Vps18 PF05131.14 CAR25091.1 - 1.9e-36 125.1 0.0 1.9e-35 121.9 0.0 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CAR25091.1 - 3.7e-06 26.9 7.4 6.1e-06 26.2 0.1 3.4 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 CAR25091.1 - 0.0025 17.6 4.3 0.0078 16.0 4.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 CAR25091.1 - 0.0035 17.8 1.0 0.0074 16.7 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 CAR25091.1 - 0.0035 17.6 4.1 0.0035 17.6 4.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CAR25091.1 - 0.0035 17.1 3.7 0.011 15.4 3.7 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CAR25091.1 - 0.0043 17.0 2.5 0.011 15.8 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAR25091.1 - 0.0062 16.5 2.7 0.0062 16.5 2.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR25091.1 - 0.096 12.6 2.7 0.3 11.0 2.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CAR25091.1 - 0.11 12.5 4.4 0.24 11.4 4.4 1.6 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 CAR25091.1 - 0.14 12.5 0.9 0.4 11.0 0.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CAR25091.1 - 7.5 6.3 11.4 0.022 14.4 1.2 2.1 3 0 0 3 3 2 0 Zinc-ribbon, C4HC2 type LSM PF01423.22 CAR25092.1 - 3.7e-15 55.4 0.1 4.6e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR25092.1 - 0.023 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Sec5 PF15469.6 CAR25093.1 - 3.3e-52 177.1 1.7 3.3e-52 177.1 1.7 2.1 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 CAR25093.1 - 0.017 15.2 1.8 0.063 13.4 1.8 2.1 1 0 0 1 1 1 0 Vps51/Vps67 DUF4217 PF13959.6 CAR25093.1 - 0.028 14.6 0.1 0.07 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) DUF1765 PF08578.10 CAR25093.1 - 0.11 13.0 1.2 3.4 8.1 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) Nod1 PF17114.5 CAR25093.1 - 1.4 9.1 5.9 0.82 9.8 0.3 3.2 4 0 0 4 4 4 0 Gef2-related medial cortical node protein Nod1 Fez1 PF06818.15 CAR25094.1 - 0.023 15.2 0.1 0.026 15.0 0.1 1.1 1 0 0 1 1 1 0 Fez1 COG2 PF06148.11 CAR25094.1 - 0.074 13.1 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2587 PF10759.9 CAR25094.1 - 0.091 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Cnn_1N PF07989.11 CAR25094.1 - 0.094 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 TPT PF03151.16 CAR25095.1 - 0.049 13.0 0.2 0.078 12.3 0.2 1.2 1 0 0 1 1 1 0 Triose-phosphate Transporter family PQQ_3 PF13570.6 CAR25095.1 - 0.05 14.1 0.0 3.6 8.2 0.0 3.1 4 0 0 4 4 4 0 PQQ-like domain Spermine_synth PF01564.17 CAR25096.1 - 3.6e-65 218.9 0.0 5.7e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CAR25096.1 - 2.8e-23 81.5 0.0 4.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CAR25096.1 - 0.0097 16.6 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR25096.1 - 0.054 14.2 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 CAR25096.1 - 0.066 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MTS PF05175.14 CAR25096.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF1542 PF07564.11 CAR25097.1 - 0.026 14.6 3.2 0.057 13.5 3.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF4477 PF14780.6 CAR25097.1 - 0.068 12.8 0.0 0.068 12.8 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4477) Csm2_III-A PF03750.13 CAR25097.1 - 0.093 13.6 0.2 0.093 13.6 0.2 2.5 3 0 0 3 3 3 0 Csm2 Type III-A Glyco_hydro81C PF17652.1 CAR25098.1 - 6.6e-154 512.3 7.5 9.3e-154 511.9 7.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CAR25098.1 - 1.9e-94 316.4 7.1 2.9e-94 315.9 7.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain PPC PF04151.15 CAR25098.1 - 0.56 11.3 4.3 0.42 11.8 0.6 2.7 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Sec1 PF00995.23 CAR25099.1 - 2e-90 304.7 0.0 2.3e-90 304.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Diphthami_syn_2 PF01902.17 CAR25101.1 - 1.5e-32 112.9 0.0 3.8e-32 111.6 0.0 1.6 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CAR25101.1 - 3e-14 53.0 0.0 3.7e-09 36.6 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP Pro_dh PF01619.18 CAR25102.1 - 9.1e-60 202.7 0.0 1.3e-59 202.2 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase SLS PF14611.6 CAR25104.1 - 6.4e-41 140.6 0.0 1.2e-40 139.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator SH3_9 PF14604.6 CAR25105.1 - 2.3e-12 46.5 0.2 4.2e-12 45.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAR25105.1 - 7.6e-12 44.7 0.0 1.9e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAR25105.1 - 6.5e-06 25.7 0.0 1.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain TPR_2 PF07719.17 CAR25106.1 - 5.9e-08 32.2 0.9 0.067 13.3 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR25106.1 - 1.8e-06 28.4 0.5 0.047 14.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR25106.1 - 2e-06 27.5 0.2 0.25 11.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR25106.1 - 2.3e-06 27.2 0.0 0.15 12.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR25106.1 - 2.4e-05 24.8 0.1 0.54 11.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR25106.1 - 0.00014 21.7 0.1 0.16 12.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR25106.1 - 0.0084 16.7 0.1 7.6 7.3 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR25106.1 - 0.0096 15.6 4.2 0.072 12.8 0.1 3.6 5 0 0 5 5 5 1 TPR repeat ANAPC3 PF12895.7 CAR25106.1 - 0.01 16.1 0.2 0.86 9.9 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CAR25106.1 - 0.014 15.7 0.0 13 6.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF410 PF04190.13 CAR25106.1 - 0.019 14.8 0.9 2 8.2 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF410) TBCC_N PF16752.5 CAR25106.1 - 0.042 14.3 4.1 1.8 9.0 0.3 3.1 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain TPR_MalT PF17874.1 CAR25106.1 - 0.054 12.9 0.1 11 5.3 0.0 2.4 3 0 0 3 3 3 0 MalT-like TPR region TPR_12 PF13424.6 CAR25106.1 - 0.067 13.5 0.1 8.9 6.7 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 CAR25106.1 - 0.21 10.8 0.4 3.1 6.9 0.0 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat AA_permease PF00324.21 CAR25107.1 - 9.5e-80 268.5 43.6 8.3e-79 265.4 43.6 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR25107.1 - 2.8e-22 79.1 40.7 8.6e-22 77.5 40.7 1.7 1 1 0 1 1 1 1 Amino acid permease Na_H_Exchanger PF00999.21 CAR25108.1 - 3.4e-85 286.1 25.1 4.1e-85 285.9 25.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 CAR25108.1 - 1.5e-71 242.0 54.8 1.6e-61 209.0 30.8 2.8 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Metal_resist PF13801.6 CAR25108.1 - 0.016 15.4 0.2 0.056 13.6 0.2 1.9 1 0 0 1 1 1 0 Heavy-metal resistance SAC3_GANP PF03399.16 CAR25109.1 - 2.2e-101 339.1 0.3 4.6e-101 338.1 0.3 1.6 1 0 0 1 1 1 1 SAC3/GANP family SAC3 PF12209.8 CAR25109.1 - 1.3e-14 54.1 0.9 1.3e-14 54.1 0.9 2.5 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain CSN8_PSD8_EIF3K PF10075.9 CAR25109.1 - 0.0026 17.7 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family FAM199X PF15814.5 CAR25109.1 - 4 6.4 8.2 0.19 10.8 1.4 2.2 2 0 0 2 2 2 0 Protein family FAM199X Methyltransf_16 PF10294.9 CAR25110.1 - 4.5e-05 23.2 0.8 0.023 14.5 0.1 2.4 1 1 1 2 2 2 2 Lysine methyltransferase Semialdhyde_dhC PF02774.18 CAR25111.1 - 1.3e-40 139.5 0.0 1.8e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CAR25111.1 - 2.2e-31 108.8 0.0 3.8e-31 108.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CAR25111.1 - 0.034 14.4 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 CAR25111.1 - 0.037 14.7 0.0 0.11 13.2 0.0 1.9 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 CAR25111.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNA_polI_A14 PF08203.11 CAR25112.1 - 1.8e-15 57.4 0.1 2.2e-07 31.5 0.1 2.0 1 1 1 2 2 2 2 Yeast RNA polymerase I subunit RPA14 Pro_isomerase PF00160.21 CAR25113.1 - 7.6e-48 162.8 0.0 9.1e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 CAR25114.1 - 1.9e-31 108.7 0.1 2.8e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 ENTH domain eIF3_subunit PF08597.10 CAR25114.1 - 0.26 11.2 16.3 0.083 12.8 8.1 2.3 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 CAR25114.1 - 4.4 7.8 12.8 5.4 7.5 3.5 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3246 PF11596.8 CAR25114.1 - 6.5 6.1 21.1 0.73 9.2 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3246) Spt5_N PF11942.8 CAR25114.1 - 9.3 7.3 15.9 1.9 9.5 8.3 2.7 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal RWD PF05773.22 CAR25115.1 - 2.3e-27 95.6 5.7 3.9e-27 94.9 5.7 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CAR25115.1 - 0.00012 22.5 3.0 0.00012 22.5 3.0 2.4 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 UFC1 PF08694.11 CAR25115.1 - 0.14 11.8 0.1 0.57 9.8 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 GOLD_2 PF13897.6 CAR25115.1 - 9.4 6.7 8.2 4.1 7.9 0.3 2.2 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking Sortilin-Vps10 PF15902.5 CAR25116.1 - 2.2e-30 105.9 0.0 4.7e-30 104.8 0.0 1.5 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 CAR25116.1 - 1.7e-05 24.1 21.8 0.098 12.7 1.3 6.1 6 0 0 6 6 6 4 BNR/Asp-box repeat CHB_HEX_C PF03174.13 CAR25116.1 - 0.078 13.0 0.0 5 7.2 0.0 3.0 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain Sortilin-Vps10 PF15902.5 CAR25117.1 - 9.3e-24 84.0 0.0 6.5e-23 81.2 0.0 2.6 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 CAR25117.1 - 2e-06 26.9 11.0 0.75 10.0 0.6 5.0 4 0 0 4 4 4 3 BNR/Asp-box repeat DUF4185 PF13810.6 CAR25117.1 - 0.059 12.6 0.7 0.54 9.4 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4185) BNR_6 PF15899.5 CAR25117.1 - 0.2 11.8 0.3 23 5.4 0.0 2.9 2 0 0 2 2 2 0 BNR-Asp box repeat Sortilin-Vps10 PF15902.5 CAR25118.1 - 1e-08 34.4 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 CAR25118.1 - 3.4e-05 23.2 6.6 0.26 11.4 0.0 4.5 5 0 0 5 5 5 2 BNR/Asp-box repeat DUF4185 PF13810.6 CAR25118.1 - 0.012 14.9 3.4 0.76 8.9 1.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4185) BNR_3 PF13859.6 CAR25118.1 - 0.021 14.2 0.1 0.054 12.8 0.0 1.8 2 0 0 2 2 2 0 BNR repeat-like domain Sortilin-Vps10 PF15902.5 CAR25119.1 - 1.1e-30 106.9 0.0 3.9e-17 62.2 0.0 2.4 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 CAR25119.1 - 5.5e-05 22.6 20.5 0.63 10.3 0.3 6.9 7 0 0 7 7 7 3 BNR/Asp-box repeat BNR_2 PF13088.6 CAR25119.1 - 0.0023 17.3 1.0 3.9 6.7 0.0 4.1 3 2 1 4 4 4 2 BNR repeat-like domain PSII_BNR PF14870.6 CAR25119.1 - 0.0041 16.4 0.2 0.33 10.2 0.0 3.1 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.16 CAR25119.1 - 0.35 10.9 1.4 15 5.6 0.0 3.7 4 1 1 5 5 5 0 Mo-co oxidoreductase dimerisation domain DUF4185 PF13810.6 CAR25119.1 - 0.49 9.6 2.0 9 5.4 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4185) Sortilin-Vps10 PF15902.5 CAR25120.1 - 2.6e-13 49.6 0.0 3.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, zf-CCCH PF00642.24 CAR25121.1 - 1.5e-17 63.0 17.4 8.4e-09 35.1 3.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAR25121.1 - 2.1e-08 33.7 16.3 3.9e-05 23.3 2.4 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAR25121.1 - 8.6e-08 32.0 19.9 0.00032 20.6 5.4 2.4 2 0 0 2 2 2 2 Zinc finger domain Defensin_int PF17858.1 CAR25121.1 - 0.1 12.6 3.3 0.12 12.3 1.5 2.1 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide Torus PF16131.5 CAR25121.1 - 0.15 12.8 19.1 1.4 9.6 9.5 3.0 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 CAR25121.1 - 2 9.0 14.1 3.5 8.2 1.9 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger TFR_dimer PF04253.15 CAR25122.1 - 2.3e-21 76.1 0.0 4.2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CAR25122.1 - 3.1e-21 76.0 0.0 4.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CAR25122.1 - 7.9e-12 45.0 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 CAR25122.1 - 0.0016 17.9 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.28 CAR25122.1 - 0.049 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Mcp5_PH PF12814.7 CAR25123.1 - 1.1e-44 151.5 0.2 2.7e-44 150.2 0.2 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ADIP PF11559.8 CAR25123.1 - 0.00024 21.2 9.7 0.00024 21.2 9.7 4.7 1 1 2 4 4 4 2 Afadin- and alpha -actinin-Binding Orthopox_F6 PF06601.12 CAR25123.1 - 0.11 12.6 0.1 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus F6 protein CtIP_N PF10482.9 CAR25123.1 - 0.26 11.3 11.6 3.1 7.9 11.6 3.1 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain NYD-SP28_assoc PF14775.6 CAR25123.1 - 1.1 9.5 7.6 0.74 10.0 1.5 3.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain YabA PF06156.13 CAR25123.1 - 3.4 8.3 19.6 0.32 11.7 1.8 4.2 3 0 0 3 3 3 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 CAR25123.1 - 3.8 7.6 35.4 0.51 10.4 6.8 4.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein E2F_CC-MB PF16421.5 CAR25123.1 - 5.7 7.4 10.2 14 6.2 0.5 4.5 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DUF2968 PF11180.8 CAR25123.1 - 6.4 6.4 17.4 8 6.1 5.7 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Jnk-SapK_ap_N PF09744.9 CAR25123.1 - 8 6.7 34.7 0.33 11.2 6.4 5.0 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 Slx4 PF09494.10 CAR25124.1 - 8.7e-18 64.0 0.1 3.4e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 Slx4 endonuclease 2-oxoacid_dh PF00198.23 CAR25125.1 - 1.9e-80 269.7 0.1 2.8e-80 269.1 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CAR25125.1 - 1.6e-16 59.9 0.4 2.9e-16 59.0 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CAR25125.1 - 3e-05 23.8 0.1 0.00076 19.3 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 CAR25125.1 - 0.00037 21.2 0.1 0.017 15.8 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 CAR25125.1 - 0.0043 16.9 0.2 0.012 15.5 0.1 1.8 1 1 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CAR25125.1 - 0.011 15.6 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ndc1_Nup PF09531.10 CAR25125.1 - 0.28 9.8 4.3 0.39 9.3 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YL1 PF05764.13 CAR25125.1 - 0.3 11.2 5.4 0.45 10.6 5.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TraF PF13728.6 CAR25125.1 - 1.8 8.3 0.0 1.8 8.3 0.0 3.3 1 1 2 3 3 3 0 F plasmid transfer operon protein Choline_kinase PF01633.20 CAR25126.1 - 5.3e-64 215.7 0.0 7.3e-64 215.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 CAR25126.1 - 7.6e-11 41.5 0.0 1.9e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 CAR25126.1 - 3.3e-09 37.0 0.0 4.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family HVSL PF09749.9 CAR25127.1 - 5.4e-23 81.7 0.0 8.4e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein zf-C2H2 PF00096.26 CAR25128.1 - 3e-10 40.0 16.7 0.00054 20.3 1.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR25128.1 - 1.7e-06 28.4 13.1 0.065 14.1 0.5 4.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAR25128.1 - 0.018 15.0 1.1 2.4 8.3 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Trm5_N PF18093.1 CAR25128.1 - 0.039 13.8 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain zf-H2C2_2 PF13465.6 CAR25128.1 - 0.21 12.1 0.1 0.21 12.1 0.1 3.9 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CAR25128.1 - 0.27 11.9 0.1 0.27 11.9 0.1 2.6 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats WD40 PF00400.32 CAR25129.1 - 5.2e-52 172.7 36.7 2.2e-06 28.3 0.3 11.3 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25129.1 - 1.7e-18 66.7 6.8 0.00079 19.7 0.0 7.6 4 3 2 8 8 7 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CAR25129.1 - 9.8e-18 64.4 0.1 1.9e-17 63.5 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.8 CAR25129.1 - 4e-10 39.0 6.2 0.012 14.3 0.0 5.9 4 2 2 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CAR25129.1 - 9.9e-10 38.2 0.4 0.011 15.0 0.1 4.6 3 2 1 5 5 5 2 WD40-like domain eIF2A PF08662.11 CAR25129.1 - 0.00021 21.3 0.8 0.2 11.5 0.0 4.3 3 2 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 CAR25129.1 - 0.00026 20.8 4.3 0.78 9.4 0.0 4.2 5 0 0 5 5 5 2 TUP1-like enhancer of split Ge1_WD40 PF16529.5 CAR25129.1 - 0.002 17.1 8.6 2.3 7.1 0.0 6.1 4 3 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TolB_like PF15869.5 CAR25129.1 - 0.0056 16.0 0.0 3.8 6.7 0.0 3.4 3 0 0 3 3 3 1 TolB-like 6-blade propeller-like PALB2_WD40 PF16756.5 CAR25129.1 - 0.016 14.2 8.0 1.7 7.5 0.1 4.8 4 2 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CAR25129.1 - 0.019 13.3 0.0 1.5 7.1 0.0 2.7 2 2 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Microvir_J PF04726.13 CAR25129.1 - 0.14 12.1 2.0 0.29 11.2 2.0 1.5 1 0 0 1 1 1 0 Microvirus J protein TFIID_20kDa PF03847.13 CAR25130.1 - 1.9e-32 111.6 0.5 3.3e-32 110.8 0.5 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 CAR25130.1 - 0.0015 18.6 0.2 0.0065 16.5 0.0 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 CAR25130.1 - 0.0016 18.8 1.1 0.0061 16.9 0.0 2.6 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 IL3 PF02059.15 CAR25130.1 - 0.026 14.6 0.7 0.1 12.7 0.7 2.0 1 0 0 1 1 1 0 Interleukin-3 CBFD_NFYB_HMF PF00808.23 CAR25130.1 - 0.058 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mod_r PF07200.13 CAR25130.1 - 8.7 6.4 11.2 0.95 9.6 3.2 2.6 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cullin_binding PF03556.15 CAR25131.1 - 2.4e-31 108.7 2.5 5.2e-31 107.6 2.5 1.6 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 CAR25131.1 - 4.5e-10 39.2 2.0 6.2e-10 38.7 0.5 2.1 2 0 0 2 2 2 1 UBA-like domain ANAPC2 PF08672.11 CAR25132.1 - 3.1e-21 75.6 0.3 2.7e-20 72.6 0.0 2.8 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 CAR25132.1 - 2.2e-10 39.8 1.8 2.2e-10 39.8 1.8 1.7 2 0 0 2 2 2 1 Cullin family HTH_9 PF08221.11 CAR25132.1 - 7.9e-05 22.7 0.3 0.0008 19.5 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain FWWh PF14922.6 CAR25132.1 - 0.057 13.4 2.6 0.18 11.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function Cylicin_N PF15241.6 CAR25132.1 - 0.085 13.0 0.2 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 Cylicin N-terminus TrmB PF01978.19 CAR25132.1 - 0.097 12.6 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_45 PF14947.6 CAR25132.1 - 0.18 11.8 0.7 4.4 7.4 0.1 3.3 3 0 0 3 3 3 0 Winged helix-turn-helix GATase PF00117.28 CAR25133.1 - 8.8e-11 41.9 0.0 1.1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Asp PF00026.23 CAR25134.1 - 5.1e-71 239.7 6.7 5.1e-71 239.7 6.7 2.5 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR25134.1 - 1.3e-10 41.8 0.9 1.3e-10 41.8 0.9 2.5 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CAR25134.1 - 0.003 18.1 0.2 3.8 8.1 0.0 4.1 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease DUF5305 PF17231.2 CAR25134.1 - 0.099 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Asp_protease_2 PF13650.6 CAR25134.1 - 0.12 13.0 4.5 8.1 7.2 0.1 4.0 4 0 0 4 4 4 0 Aspartyl protease zf-RING_2 PF13639.6 CAR25135.1 - 1.2e-11 44.7 7.4 3.4e-10 40.1 2.7 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CAR25135.1 - 9.6e-09 35.4 5.7 1.7e-07 31.4 1.7 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CAR25135.1 - 2.3e-07 30.6 0.5 2.3e-07 30.6 0.5 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CAR25135.1 - 5.4e-07 29.5 6.2 3e-06 27.1 0.6 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR25135.1 - 2.6e-06 27.2 7.3 7.4e-06 25.7 3.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR25135.1 - 1.2e-05 25.0 4.1 1.9e-05 24.4 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR25135.1 - 1.6e-05 24.7 5.4 1.9e-05 24.4 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR25135.1 - 8e-05 22.5 4.7 0.00015 21.6 1.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CAR25135.1 - 0.00024 21.2 1.0 0.00024 21.2 1.0 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CAR25135.1 - 0.025 14.6 0.7 0.16 12.0 0.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CAR25135.1 - 0.096 12.5 8.1 0.18 11.5 0.2 2.7 3 0 0 3 3 3 0 RING-like zinc finger U-box PF04564.15 CAR25135.1 - 0.13 12.4 0.4 0.47 10.7 0.0 2.1 2 0 0 2 2 1 0 U-box domain Rtf2 PF04641.12 CAR25135.1 - 0.24 10.7 11.8 0.42 9.9 0.0 2.7 2 1 1 3 3 3 0 Rtf2 RING-finger FANCL_C PF11793.8 CAR25135.1 - 1.6 9.0 3.6 16 5.8 0.0 2.9 2 1 1 3 3 3 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CAR25135.1 - 2.1 8.2 4.8 1.4 8.7 2.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CAR25135.1 - 3 8.1 4.1 0.75 10.0 0.1 2.0 3 0 0 3 3 2 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 CAR25135.1 - 5 6.8 5.2 0.56 9.9 0.9 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CAR25136.1 - 3.8e-15 56.0 15.1 0.0015 19.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Mod_r PF07200.13 CAR25137.1 - 2.1e-12 47.4 13.2 2.7e-12 47.0 13.2 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FAD-SLDH PF12318.8 CAR25137.1 - 0.011 15.9 1.1 0.026 14.6 0.6 1.7 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase APG6_N PF17675.1 CAR25137.1 - 0.066 13.7 8.0 0.094 13.2 8.0 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 CAR25137.1 - 0.16 10.6 1.8 0.18 10.4 1.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A eIF3_N PF09440.10 CAR25137.1 - 0.18 12.2 5.0 0.11 13.0 2.7 1.8 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Jnk-SapK_ap_N PF09744.9 CAR25137.1 - 1.5 9.0 12.7 1 9.6 10.1 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Abhydrolase_2 PF02230.16 CAR25138.1 - 2.2e-61 207.4 0.0 2.5e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CAR25138.1 - 1.3e-09 38.0 0.0 3.1e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CAR25138.1 - 4.3e-09 37.3 0.1 5.1e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CAR25138.1 - 2.2e-06 27.4 0.0 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CAR25138.1 - 2.5e-06 27.3 0.2 2.8e-05 23.9 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR25138.1 - 4.8e-05 22.8 0.0 0.36 10.0 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CAR25138.1 - 0.0058 16.5 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fe_dep_repr_C PF02742.15 CAR25138.1 - 0.023 14.7 0.0 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain Peptidase_S9 PF00326.21 CAR25138.1 - 0.027 14.0 0.1 2 7.8 0.0 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 CAR25138.1 - 0.066 13.1 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) BAAT_C PF08840.11 CAR25138.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.8 CAR25138.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Dopey_N PF04118.14 CAR25139.1 - 7e-111 370.2 0.8 1.7e-110 369.0 0.2 2.0 2 0 0 2 2 2 1 Dopey, N-terminal MTS PF05175.14 CAR25140.1 - 4.6e-07 29.5 0.0 1e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 CAR25140.1 - 0.00012 22.0 0.0 0.011 15.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CAR25140.1 - 0.013 14.9 0.0 0.09 12.2 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CAR25140.1 - 0.037 13.8 0.0 0.071 12.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 CAR25140.1 - 0.037 13.8 0.0 0.07 12.9 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF938) ubiquitin PF00240.23 CAR25141.1 - 2.8e-23 81.5 0.2 3e-23 81.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAR25141.1 - 4e-15 55.4 0.2 4.3e-15 55.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR25141.1 - 0.00041 20.8 0.1 0.0013 19.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAR25141.1 - 0.0013 18.6 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CAR25141.1 - 0.033 14.2 0.1 2.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain TUG-UBL1 PF11470.8 CAR25141.1 - 0.038 14.2 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 TUG ubiquitin-like domain TPR_14 PF13428.6 CAR25142.1 - 7.2e-21 73.1 12.5 0.037 14.9 0.3 10.8 8 3 4 12 12 11 6 Tetratricopeptide repeat HAT PF02184.16 CAR25142.1 - 2.2e-14 53.1 29.2 2.1e-05 24.4 0.8 7.2 7 0 0 7 7 7 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 CAR25142.1 - 5.1e-11 42.9 2.0 0.00021 21.8 0.0 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR25142.1 - 9e-08 32.0 7.3 0.24 11.9 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.14 CAR25142.1 - 4e-06 27.0 10.5 0.091 12.7 0.2 5.7 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 CAR25142.1 - 8.1e-05 22.0 6.1 0.00043 19.6 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR25142.1 - 0.00097 19.2 9.1 7.9 7.0 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR25142.1 - 0.02 15.2 9.3 53 4.2 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR25142.1 - 0.045 14.4 4.4 31 5.3 0.1 4.9 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR25142.1 - 0.25 11.6 15.0 5.2 7.4 0.3 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CAR25142.1 - 0.53 10.4 16.2 0.26 11.4 3.4 5.1 4 2 2 6 6 6 0 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.6 CAR25142.1 - 0.81 10.5 10.0 38 5.2 0.1 6.3 7 0 0 7 7 6 0 Tetratricopeptide repeat SF1-HH PF16275.5 CAR25143.1 - 7.4e-43 145.5 1.6 1.6e-42 144.4 1.6 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CAR25143.1 - 7.2e-07 28.9 0.2 2e-06 27.5 0.2 1.8 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 CAR25143.1 - 4.1e-05 23.5 6.1 0.0044 17.0 1.8 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 CAR25143.1 - 0.085 13.0 8.9 0.82 9.9 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF1660 PF07874.11 CAR25143.1 - 0.096 13.2 0.7 0.24 11.9 0.7 1.6 1 0 0 1 1 1 0 Prophage protein (DUF1660) zf-CCHC_4 PF14392.6 CAR25143.1 - 0.97 9.2 5.1 1.5 8.6 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle Lar_restr_allev PF14354.6 CAR25143.1 - 1 9.8 8.3 0.081 13.3 3.3 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar Lactamase_B_6 PF16661.5 CAR25144.1 - 2.5e-68 229.3 0.0 4.1e-68 228.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CAR25144.1 - 7e-24 84.9 9.4 1.4e-21 77.5 0.2 3.5 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CAR25144.1 - 0.056 13.7 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Beta-Casp domain efThoc1 PF11957.8 CAR25145.1 - 1.4e-101 340.7 6.1 1.4e-101 340.7 6.1 1.6 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor FAD_oxidored PF12831.7 CAR25145.1 - 1.3 8.3 3.5 2 7.6 3.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Avl9 PF09794.9 CAR25146.1 - 1.7e-145 484.5 0.2 1.7e-145 484.5 0.2 1.5 2 0 0 2 2 2 1 Transport protein Avl9 DUF2347 PF09804.9 CAR25146.1 - 1e-06 28.5 8.4 0.0022 17.6 0.7 3.7 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 CAR25146.1 - 8.2e-06 25.8 0.2 0.066 13.2 0.0 2.7 3 0 0 3 3 3 2 Stabilization of polarity axis Afi1 PF07792.12 CAR25146.1 - 0.0091 16.5 0.3 0.0091 16.5 0.3 2.9 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 CAR25146.1 - 0.056 13.4 0.3 0.71 9.8 0.2 2.2 1 1 0 2 2 2 0 DENN (AEX-3) domain Rgp1 PF08737.10 CAR25147.1 - 9.9e-94 314.9 2.3 1.5e-93 314.3 2.3 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.22 CAR25147.1 - 0.0052 17.2 0.0 0.38 11.2 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain CENP-Q PF13094.6 CAR25147.1 - 0.13 12.5 0.8 0.31 11.2 0.8 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ABC_membrane PF00664.23 CAR25148.1 - 5.1e-86 288.7 38.6 2.2e-48 165.3 16.9 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAR25148.1 - 1.1e-49 168.5 0.0 8.1e-31 107.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR25148.1 - 7.3e-10 38.7 5.6 0.002 17.6 0.1 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CAR25148.1 - 4.8e-06 26.6 0.2 0.099 12.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CAR25148.1 - 2.2e-05 25.0 0.3 0.015 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR25148.1 - 2.5e-05 23.9 0.7 0.071 12.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR25148.1 - 7.9e-05 22.6 0.1 0.057 13.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CAR25148.1 - 0.00033 20.6 2.4 0.036 13.9 0.0 3.0 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CAR25148.1 - 0.00063 20.2 0.3 1.3 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CAR25148.1 - 0.0014 18.5 0.1 0.29 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAR25148.1 - 0.0021 18.4 0.8 1.8 8.8 0.2 2.9 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 CAR25148.1 - 0.024 14.7 2.2 0.37 10.8 0.3 2.6 2 0 0 2 2 2 0 Dynamin family AIG1 PF04548.16 CAR25148.1 - 0.025 13.9 0.9 1.2 8.4 0.1 3.0 3 0 0 3 3 3 0 AIG1 family DUF2523 PF10734.9 CAR25148.1 - 0.031 14.9 2.2 5.3 7.7 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2523) AAA_7 PF12775.7 CAR25148.1 - 0.055 13.0 0.1 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 CAR25148.1 - 0.061 13.4 5.0 0.5 10.4 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain Zeta_toxin PF06414.12 CAR25148.1 - 0.12 11.6 0.3 2.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CAR25148.1 - 0.13 11.9 1.8 9.2 5.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CAR25148.1 - 0.15 11.8 0.4 7.7 6.2 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Pkinase PF00069.25 CAR25149.1 - 3.7e-67 226.5 0.0 5.5e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25149.1 - 6.1e-31 107.6 0.0 9.4e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR25149.1 - 2.5e-06 26.7 0.1 4.2e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR25149.1 - 9e-05 21.9 0.2 0.00034 20.0 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR25149.1 - 0.0013 18.7 3.1 0.0024 17.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CAR25149.1 - 0.0035 16.7 0.0 0.31 10.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Ribosomal_60s PF00428.19 CAR25149.1 - 0.021 15.4 0.1 0.14 12.8 0.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein RIO1 PF01163.22 CAR25149.1 - 0.048 13.2 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CAR25149.1 - 0.059 13.0 0.0 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CAR25149.1 - 0.089 11.5 0.9 0.75 8.5 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase DUF4820 PF16091.5 CAR25149.1 - 2.1 7.6 7.5 3.7 6.8 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Flocculin_t3 PF13928.6 CAR25150.1 - 5.8e-17 61.9 15.8 5.8e-17 61.9 15.8 3.2 3 1 0 3 3 3 1 Flocculin type 3 repeat EMI PF07546.13 CAR25150.1 - 2.1 9.1 5.2 15 6.4 5.2 2.1 1 1 0 1 1 1 0 EMI domain BTB_2 PF02214.22 CAR25151.1 - 5.8e-06 26.6 0.0 0.0019 18.5 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain F-box PF00646.33 CAR25152.1 - 0.00029 20.6 0.8 0.0012 18.7 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CAR25152.1 - 0.00035 20.4 0.3 0.00094 19.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like FIN1 PF17300.2 CAR25153.1 - 3.8e-46 157.6 14.4 5.5e-46 157.0 14.4 1.2 1 0 0 1 1 1 1 Filaments in between nuclei protein-1 Oest_recep PF02159.15 CAR25153.1 - 0.11 13.0 2.7 0.16 12.4 2.1 1.6 1 1 0 1 1 1 0 Oestrogen receptor DNA_pol_A_exo1 PF01612.20 CAR25154.1 - 0.00011 22.0 0.1 0.00095 18.9 0.1 2.3 1 1 0 1 1 1 1 3'-5' exonuclease EloA-BP1 PF15870.5 CAR25154.1 - 0.037 14.3 0.8 0.076 13.3 0.8 1.4 1 0 0 1 1 1 0 ElonginA binding-protein 1 Dermcidin PF15291.6 CAR25154.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide CHORD PF04968.12 CAR25154.1 - 0.11 13.2 5.6 0.21 12.3 5.6 1.5 1 0 0 1 1 1 0 CHORD AAA_5 PF07728.14 CAR25155.1 - 2.1e-130 429.4 0.1 3.5e-21 75.6 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CAR25155.1 - 1.9e-53 179.1 3.0 7e-20 71.2 0.0 5.6 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_3 PF07726.11 CAR25155.1 - 3.3e-34 117.6 0.0 4e-11 42.9 0.0 8.0 8 0 0 8 8 7 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CAR25155.1 - 3.7e-33 113.8 0.0 5.7e-31 106.7 0.0 3.4 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_7 PF12775.7 CAR25155.1 - 1e-32 113.1 7.6 5.4e-07 29.3 0.1 7.4 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA PF00004.29 CAR25155.1 - 3.7e-30 105.1 0.0 3.8e-05 24.1 0.0 7.3 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CAR25155.1 - 1.4e-22 80.1 0.0 9.6e-06 25.7 0.0 8.0 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 CAR25155.1 - 1.5e-22 80.8 19.0 0.00011 22.6 0.3 9.1 8 2 0 9 9 7 5 AAA ATPase domain Sigma54_activat PF00158.26 CAR25155.1 - 1.7e-22 79.9 0.1 3.4e-05 23.6 0.0 6.0 6 0 0 6 6 5 5 Sigma-54 interaction domain AAA_6 PF12774.7 CAR25155.1 - 7.5e-22 77.7 4.2 0.0079 15.2 0.0 10.1 9 2 0 9 9 8 5 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 CAR25155.1 - 2e-18 66.8 0.0 0.097 12.4 0.0 7.2 7 0 0 7 7 6 5 AAA domain AAA_14 PF13173.6 CAR25155.1 - 3.3e-16 59.5 0.1 0.024 14.7 0.0 7.7 7 1 1 8 8 6 3 AAA domain AAA_18 PF13238.6 CAR25155.1 - 6.3e-16 59.1 10.9 0.089 13.3 0.0 8.3 7 0 0 7 7 6 5 AAA domain AAA_22 PF13401.6 CAR25155.1 - 7.8e-16 58.6 2.7 0.027 14.8 0.0 8.3 7 0 0 7 7 6 3 AAA domain TsaE PF02367.17 CAR25155.1 - 1.1e-15 57.8 8.5 0.01 15.8 0.1 7.4 8 0 0 8 8 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CAR25155.1 - 1.8e-15 57.3 2.0 0.022 14.9 0.0 6.5 6 0 0 6 6 6 3 Sigma-54 interaction domain T2SSE PF00437.20 CAR25155.1 - 1.1e-13 50.9 3.7 0.015 14.3 0.0 6.2 6 0 0 6 6 6 3 Type II/IV secretion system protein AAA_33 PF13671.6 CAR25155.1 - 1.6e-11 44.6 0.4 0.31 11.2 0.0 6.6 6 0 0 6 6 6 2 AAA domain RNA_helicase PF00910.22 CAR25155.1 - 1.6e-11 44.6 6.1 0.11 12.9 0.0 7.7 7 0 0 7 7 6 2 RNA helicase ABC_tran PF00005.27 CAR25155.1 - 2.3e-11 44.3 23.0 0.0016 18.9 0.0 7.6 7 1 0 7 7 6 3 ABC transporter RsgA_GTPase PF03193.16 CAR25155.1 - 1.6e-10 41.1 8.9 0.11 12.3 0.2 5.7 5 0 0 5 5 5 4 RsgA GTPase Zeta_toxin PF06414.12 CAR25155.1 - 1.8e-10 40.4 5.9 0.47 9.7 0.0 7.6 7 0 0 7 7 7 2 Zeta toxin AAA_25 PF13481.6 CAR25155.1 - 2.9e-10 40.1 0.5 0.17 11.4 0.0 4.9 5 0 0 5 5 4 3 AAA domain AAA_19 PF13245.6 CAR25155.1 - 2.7e-09 37.5 5.0 0.78 10.1 0.3 6.3 6 0 0 6 6 5 2 AAA domain NACHT PF05729.12 CAR25155.1 - 3.2e-09 36.9 9.1 0.15 11.9 0.1 6.0 6 0 0 6 6 4 4 NACHT domain RuvB_N PF05496.12 CAR25155.1 - 7.3e-09 35.6 1.3 0.2 11.4 0.0 5.6 7 0 0 7 7 4 3 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR25155.1 - 1.4e-08 35.2 3.5 3.3 7.9 0.0 6.9 6 0 0 6 6 6 0 AAA domain Mg_chelatase PF01078.21 CAR25155.1 - 1.9e-08 33.9 0.5 16 4.8 0.0 8.3 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CAR25155.1 - 3.5e-08 32.9 3.2 0.074 12.2 0.0 5.4 5 0 0 5 5 5 2 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CAR25155.1 - 4.6e-08 32.9 6.8 0.13 12.0 0.1 5.8 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 CAR25155.1 - 1.1e-07 32.0 5.2 0.1 12.5 0.1 6.4 6 0 0 6 6 6 1 Rad17 P-loop domain Roc PF08477.13 CAR25155.1 - 2.1e-07 31.2 6.4 1.5 9.0 0.1 6.8 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 CAR25155.1 - 2.1e-07 30.9 0.1 9.1 6.0 0.0 6.0 6 0 0 6 6 6 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 CAR25155.1 - 4.6e-07 29.9 3.6 27 4.9 0.0 6.9 6 0 0 6 6 6 0 50S ribosome-binding GTPase TIP49 PF06068.13 CAR25155.1 - 7e-07 28.8 2.1 2.4 7.2 0.0 5.5 6 0 0 6 6 6 1 TIP49 P-loop domain ATP-synt_ab PF00006.25 CAR25155.1 - 1.8e-06 27.7 0.0 1.9 8.1 0.0 3.7 2 1 1 3 3 3 2 ATP synthase alpha/beta family, nucleotide-binding domain TniB PF05621.11 CAR25155.1 - 2.2e-06 27.2 1.5 2 7.8 0.0 6.1 7 0 0 7 7 6 1 Bacterial TniB protein MCM PF00493.23 CAR25155.1 - 2.6e-06 26.7 0.8 0.29 10.2 0.0 5.2 5 0 0 5 5 5 1 MCM P-loop domain AAA_29 PF13555.6 CAR25155.1 - 3e-06 26.9 2.3 9.2 6.1 0.0 6.2 6 0 0 6 6 6 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 CAR25155.1 - 1.1e-05 24.9 0.8 2.1 7.5 0.0 5.5 6 0 0 6 6 5 1 KAP family P-loop domain ResIII PF04851.15 CAR25155.1 - 1.2e-05 25.3 6.6 0.24 11.4 0.0 5.5 5 1 0 5 5 3 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 CAR25155.1 - 2.5e-05 24.3 0.0 6.5 6.5 0.0 5.0 5 0 0 5 5 4 0 Bacterial dnaA protein PhoH PF02562.16 CAR25155.1 - 3.5e-05 23.4 0.7 4 6.8 0.0 4.6 4 0 0 4 4 4 0 PhoH-like protein SRP54 PF00448.22 CAR25155.1 - 7.1e-05 22.5 9.6 0.52 9.9 0.1 5.1 6 0 0 6 6 4 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CAR25155.1 - 0.00019 21.2 3.9 6.8 6.4 0.0 5.4 6 0 0 6 6 5 0 AAA domain AAA_8 PF12780.7 CAR25155.1 - 0.0013 18.1 0.4 2.6 7.3 0.0 5.2 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 ATP_bind_1 PF03029.17 CAR25155.1 - 0.0015 18.3 9.8 3.5 7.3 0.1 5.7 5 0 0 5 5 5 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CAR25155.1 - 0.002 18.1 10.7 1.6 8.6 0.2 5.4 5 0 0 5 5 5 1 NTPase DEAD PF00270.29 CAR25155.1 - 0.0028 17.5 0.4 10 5.8 0.0 4.8 5 0 0 5 5 4 0 DEAD/DEAH box helicase CPT PF07931.12 CAR25155.1 - 0.0046 16.8 2.2 19 5.1 0.0 5.3 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein SRPRB PF09439.10 CAR25155.1 - 0.0048 16.3 8.5 5 6.5 0.1 6.2 7 0 0 7 7 6 0 Signal recognition particle receptor beta subunit PIF1 PF05970.14 CAR25155.1 - 0.0052 16.0 1.3 3 6.9 0.0 4.5 4 0 0 4 4 4 0 PIF1-like helicase NB-ARC PF00931.22 CAR25155.1 - 0.013 14.7 13.1 2.3 7.4 0.1 5.4 7 0 0 7 7 4 0 NB-ARC domain Cytidylate_kin PF02224.18 CAR25155.1 - 0.064 13.0 0.0 79 2.9 0.0 4.4 4 0 0 4 4 4 0 Cytidylate kinase PRK PF00485.18 CAR25155.1 - 0.072 12.8 0.1 15 5.2 0.0 3.5 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 CAR25155.1 - 0.086 12.4 13.5 9.6 5.8 0.0 6.0 7 0 0 7 7 6 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 CAR25155.1 - 0.1 12.5 8.4 25 4.6 0.0 5.9 6 0 0 6 6 5 0 Deoxynucleoside kinase ATPase PF06745.13 CAR25155.1 - 0.16 11.3 8.8 4.6 6.5 0.1 5.0 6 0 0 6 6 5 0 KaiC FeoB_N PF02421.18 CAR25155.1 - 0.28 10.7 7.1 42 3.6 0.0 5.4 5 1 0 5 5 5 0 Ferrous iron transport protein B MeaB PF03308.16 CAR25155.1 - 0.9 8.5 3.9 16 4.4 0.1 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CAR25155.1 - 1.9 8.5 5.8 20 5.2 0.0 4.0 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 CAR25155.1 - 2.3 8.1 9.9 32 4.4 0.1 4.9 6 0 0 6 6 3 0 Molybdopterin guanine dinucleotide synthesis protein B tRNA_int_endo PF01974.17 CAR25156.1 - 9.9e-23 80.0 0.0 2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain CDC45 PF02724.14 CAR25158.1 - 2.1e-210 700.3 0.6 2.4e-210 700.1 0.6 1.0 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 CAR25158.1 - 0.0033 17.6 5.0 0.0051 17.0 5.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Pre-PUA PF17832.1 CAR25158.1 - 0.045 14.4 0.1 0.15 12.8 0.1 1.8 1 0 0 1 1 1 0 Pre-PUA-like domain Nop14 PF04147.12 CAR25158.1 - 0.14 10.4 7.4 0.19 9.9 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4799 PF16056.5 CAR25158.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) Sigma70_ner PF04546.13 CAR25158.1 - 0.31 10.9 7.2 0.73 9.7 7.2 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region RRN3 PF05327.11 CAR25158.1 - 0.6 8.6 6.8 1.1 7.7 6.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4175 PF13779.6 CAR25158.1 - 0.64 7.8 7.0 0.9 7.4 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PDDEXK_6 PF04720.12 CAR25158.1 - 2.2 8.2 6.0 4.6 7.1 6.0 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Nop53 PF07767.11 CAR25158.1 - 3.3 7.0 14.2 5.5 6.3 14.2 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sporozoite_P67 PF05642.11 CAR25158.1 - 4.6 5.2 7.2 6.1 4.8 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 CAR25158.1 - 5 5.1 15.9 7.8 4.5 15.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Spt5_N PF11942.8 CAR25158.1 - 6 7.9 20.3 0.49 11.4 15.2 1.7 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal ANAPC9 PF12856.7 CAR25159.1 - 4.2e-07 30.2 0.0 6.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 CH PF00307.31 CAR25160.1 - 6.8e-81 267.6 0.1 3.8e-21 75.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CAR25160.1 - 2.6e-06 27.8 0.5 3e-05 24.4 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 CAR25160.1 - 8.7e-05 22.3 0.0 0.31 10.9 0.0 4.1 4 0 0 4 4 4 1 CAMSAP CH domain CH_2 PF06294.11 CAR25160.1 - 0.04 14.0 0.1 12 6.1 0.0 3.1 3 0 0 3 3 3 0 CH-like domain in sperm protein EF-hand_6 PF13405.6 CAR25160.1 - 0.11 12.5 0.2 9.5 6.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain adh_short PF00106.25 CAR25161.1 - 1.2e-11 44.5 0.0 4.7e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR25161.1 - 0.11 12.1 0.0 0.62 9.6 0.0 2.1 1 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Zn_ribbon_17 PF17120.5 CAR25162.1 - 3.4e-18 65.0 14.3 8.4e-18 63.7 14.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CAR25162.1 - 1.7e-08 35.0 1.5 9.1e-07 29.5 0.1 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat RWD PF05773.22 CAR25162.1 - 0.00029 21.1 0.2 0.00085 19.6 0.0 1.8 2 0 0 2 2 2 1 RWD domain C1_2 PF03107.16 CAR25162.1 - 0.024 14.9 2.3 0.059 13.7 2.3 1.6 1 0 0 1 1 1 0 C1 domain zf-rbx1 PF12678.7 CAR25162.1 - 0.029 14.7 4.5 0.079 13.3 4.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CAR25162.1 - 0.3 11.0 3.8 0.87 9.5 3.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_16 PF17034.5 CAR25162.1 - 0.3 11.3 6.2 0.81 9.9 6.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family zf-ANAPC11 PF12861.7 CAR25162.1 - 0.45 10.6 5.7 1.1 9.4 5.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CAR25162.1 - 0.62 10.4 9.7 1.6 9.1 9.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 CAR25162.1 - 0.81 9.8 4.3 1.8 8.6 4.3 1.6 1 0 0 1 1 1 0 Zinc-finger EPSP_synthase PF00275.20 CAR25163.1 - 6.4e-142 473.1 0.0 1e-141 472.5 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CAR25163.1 - 5.6e-100 333.8 0.0 9.4e-100 333.1 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CAR25163.1 - 3.4e-58 197.6 0.0 7.7e-58 196.5 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CAR25163.1 - 3.2e-37 128.1 0.2 7.4e-35 120.4 0.0 3.4 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 CAR25163.1 - 1.1e-22 80.1 0.0 3.7e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CAR25163.1 - 1.1e-10 41.1 0.1 2.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 CAR25163.1 - 1.2e-08 35.0 0.1 3e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 CAR25163.1 - 8.1e-07 29.2 0.0 4.1e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 CAR25163.1 - 0.038 14.2 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTP_transf_3 PF12804.7 CAR25163.1 - 0.15 12.4 2.0 0.44 10.9 0.1 2.6 4 0 0 4 4 4 0 MobA-like NTP transferase domain DHHC PF01529.20 CAR25164.1 - 8.7e-24 84.1 13.1 8.7e-24 84.1 13.1 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase CBP_BcsQ PF06564.12 CAR25166.1 - 0.054 13.0 0.1 0.066 12.7 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Abhydrolase_1 PF00561.20 CAR25167.1 - 2.7e-19 69.8 0.0 6.5e-15 55.5 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR25167.1 - 4.3e-12 47.1 0.0 8.3e-12 46.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR25167.1 - 2.1e-10 40.3 0.0 2.7e-09 36.6 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CAR25167.1 - 0.0041 17.0 0.0 0.0089 15.9 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 CAR25167.1 - 0.0083 15.7 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase DUF915 PF06028.11 CAR25167.1 - 0.013 14.8 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 CAR25167.1 - 0.089 12.3 0.0 1.3 8.5 0.0 2.5 3 0 0 3 3 3 0 Putative serine esterase (DUF676) Esterase PF00756.20 CAR25167.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 CAR25168.1 - 2.2e-39 135.1 4.5 3.9e-39 134.3 4.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR25168.1 - 6.1e-10 39.1 11.6 1.3e-09 38.0 11.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CAR25168.1 - 0.0045 15.9 7.1 0.0029 16.5 4.8 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2841 PF11001.8 CAR25169.1 - 6.4e-34 116.7 0.7 1e-33 116.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) F-box-like PF12937.7 CAR25170.1 - 1.5e-07 31.2 0.2 2.8e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR25170.1 - 0.0066 16.3 0.9 0.016 15.1 0.9 1.6 1 0 0 1 1 1 1 F-box domain HLH PF00010.26 CAR25171.1 - 0.051 13.5 0.7 0.12 12.3 0.7 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 CAR25172.1 - 1.9e-68 230.7 1.3 1.2e-66 224.8 1.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25172.1 - 1.5e-39 135.9 0.3 2.2e-38 132.0 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CAR25172.1 - 8.6e-18 63.9 0.0 1.7e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CAR25172.1 - 1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR25172.1 - 7.6e-05 22.2 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR25172.1 - 0.0088 16.0 0.0 0.073 13.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAR25172.1 - 0.01 14.8 0.1 0.021 13.8 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CAR25172.1 - 0.013 14.3 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase PHD PF00628.29 CAR25173.1 - 0.0019 18.1 1.0 0.0019 18.1 1.0 2.4 2 0 0 2 2 2 1 PHD-finger zf-CSL PF05207.13 CAR25173.1 - 0.029 14.1 1.6 0.066 12.9 1.6 1.6 1 0 0 1 1 1 0 CSL zinc finger FMO-like PF00743.19 CAR25175.1 - 3.6e-26 91.7 0.0 1.6e-15 56.6 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CAR25175.1 - 4.6e-11 42.5 0.0 8.4e-07 28.4 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CAR25175.1 - 1.2e-10 41.1 0.2 4.6e-07 29.4 0.0 3.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CAR25175.1 - 7.4e-09 35.3 0.0 0.00011 21.6 0.0 3.2 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR25175.1 - 2.7e-06 27.5 0.2 4.8e-05 23.4 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CAR25175.1 - 0.0086 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAR25175.1 - 0.059 12.6 0.0 0.42 9.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.17 CAR25175.1 - 0.09 13.4 0.2 0.32 11.6 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 CAR25175.1 - 0.14 12.8 0.0 11 6.7 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Nyv1_N PF09426.10 CAR25176.1 - 3e-55 186.0 0.1 4.7e-55 185.4 0.1 1.3 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.21 CAR25176.1 - 1.6e-26 91.9 3.1 2.5e-26 91.3 3.1 1.2 1 0 0 1 1 1 1 Synaptobrevin DUF2937 PF11157.8 CAR25176.1 - 0.0022 17.7 1.1 0.0037 17.0 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) DUF1564 PF07600.11 CAR25176.1 - 0.047 13.4 0.2 0.071 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) Oxidored_nitro PF00148.19 CAR25176.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase CBFD_NFYB_HMF PF00808.23 CAR25177.1 - 0.00018 21.7 0.2 0.0004 20.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TLP-20 PF06088.11 CAR25177.1 - 0.029 14.3 5.9 0.029 14.2 5.1 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) WRNPLPNID PF15017.6 CAR25177.1 - 1.7 9.5 7.6 5.3 8.0 5.0 2.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box FAM176 PF14851.6 CAR25177.1 - 6 6.5 6.8 7.2 6.3 4.8 1.9 2 0 0 2 2 2 0 FAM176 family TRM PF02005.16 CAR25178.1 - 1.2e-141 472.2 0.0 1.6e-141 471.9 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CAR25178.1 - 1.6e-06 28.0 0.2 3.4e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 Met-10+ like-protein CpXC PF14353.6 CAR25178.1 - 0.15 12.1 0.0 21 5.2 0.0 2.4 2 0 0 2 2 2 0 CpXC protein DUF917 PF06032.12 CAR25178.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) tRNA_U5-meth_tr PF05958.11 CAR25178.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase HMA PF00403.26 CAR25179.1 - 0.16 12.5 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Heavy-metal-associated domain MFS_1 PF07690.16 CAR25180.1 - 5.2e-43 147.3 44.0 1.3e-42 146.0 43.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR25180.1 - 3.7e-13 49.2 32.3 4.6e-13 48.8 9.5 3.4 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 CAR25180.1 - 8.4e-06 24.9 3.0 8.4e-06 24.9 3.0 2.5 2 1 0 2 2 2 1 MFS_1 like family Zip PF02535.22 CAR25180.1 - 0.38 9.9 7.4 0.15 11.3 0.7 2.8 2 1 0 2 2 2 0 ZIP Zinc transporter Sulfate_transp PF00916.20 CAR25181.1 - 1.2e-118 396.2 15.3 1.5e-118 395.9 15.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CAR25181.1 - 4.7e-05 23.0 0.0 8.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CAR25181.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 STAS domain Serglycin PF04360.12 CAR25181.1 - 1.3 9.0 4.6 14 5.6 0.7 2.5 2 0 0 2 2 2 0 Serglycin ANAPC4 PF12896.7 CAR25182.1 - 3.5e-39 134.4 0.1 5e-39 133.9 0.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 CAR25182.1 - 0.005 17.1 0.0 0.014 15.7 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain SUI1 PF01253.22 CAR25183.1 - 8.1e-21 74.3 0.1 1.8e-20 73.2 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CAR25183.1 - 7.5e-08 33.0 3.3 1.5e-07 32.0 1.5 2.5 3 0 0 3 3 3 1 Pre-PUA-like domain SWIB PF02201.18 CAR25183.1 - 0.00013 21.8 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.9 CAR25183.1 - 0.0005 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Raco_middle PF17651.1 CAR25183.1 - 0.18 11.5 0.1 0.8 9.4 0.0 1.9 2 0 0 2 2 2 0 RACo middle region Ribosomal_L1 PF00687.21 CAR25184.1 - 5.6e-33 114.4 0.1 6.5e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L34 PF00468.17 CAR25185.1 - 2.7e-20 72.1 6.5 2.7e-20 72.1 6.5 1.8 1 1 0 1 1 1 1 Ribosomal protein L34 GEP5 PF17053.5 CAR25186.1 - 1.3e-77 260.7 4.9 1.5e-77 260.4 4.9 1.1 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 Securin PF04856.13 CAR25187.1 - 4.5e-23 82.4 4.9 6.5e-23 81.9 4.9 1.3 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor DnaJ_C PF01556.18 CAR25188.1 - 5.1e-35 120.7 0.0 6.7e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR25188.1 - 1.7e-24 85.7 1.9 3.3e-24 84.8 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR25188.1 - 1e-12 48.2 14.1 1.8e-12 47.4 14.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAR25188.1 - 0.00049 20.0 9.6 0.063 13.3 1.9 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CAR25188.1 - 0.077 13.0 7.6 1.3 9.1 0.7 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 CAR25188.1 - 0.25 11.0 7.6 0.74 9.5 7.6 1.7 1 1 0 1 1 1 0 Thaumarchaeal output domain 1 Cytochrom_c3_2 PF14537.6 CAR25188.1 - 1.6 9.2 9.5 5.3 7.6 9.5 1.9 1 1 0 1 1 1 0 Cytochrome c3 Aminotran_1_2 PF00155.21 CAR25189.1 - 6.1e-41 140.8 0.0 8.6e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CAR25189.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Gaa1 PF04114.14 CAR25191.1 - 3.3e-123 412.3 10.0 4.4e-123 411.9 10.0 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DNA_ligase_A_N PF04675.14 CAR25191.1 - 0.015 15.6 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 DNA ligase N terminus SMC_N PF02463.19 CAR25193.1 - 5.1e-68 228.8 48.6 2.1e-66 223.5 48.6 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR25193.1 - 2e-25 89.4 0.0 7.4e-25 87.5 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CAR25193.1 - 3.3e-12 46.9 13.2 2.3e-05 24.4 0.0 5.0 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR25193.1 - 4.5e-05 23.1 0.0 9.8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 CAR25193.1 - 0.0017 18.6 10.5 0.0017 18.6 10.5 8.2 2 2 6 8 8 8 3 Autophagy protein 16 (ATG16) AAA_15 PF13175.6 CAR25193.1 - 0.0018 18.1 37.7 0.0018 18.1 37.7 4.1 3 1 0 3 3 3 1 AAA ATPase domain HrpB7 PF09486.10 CAR25193.1 - 0.022 15.1 36.7 0.051 14.0 3.3 6.2 4 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) Spc7 PF08317.11 CAR25193.1 - 0.076 11.9 107.3 0.12 11.3 10.8 6.7 3 2 3 7 7 7 0 Spc7 kinetochore protein PilJ PF13675.6 CAR25193.1 - 1.7 8.7 7.1 3.2 7.8 0.2 4.0 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Actin PF00022.19 CAR25194.1 - 7e-57 192.9 0.0 8e-56 189.4 0.0 1.9 1 1 0 1 1 1 1 Actin FGGY_C PF02782.16 CAR25195.1 - 3.1e-52 177.2 0.4 5.4e-52 176.4 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CAR25195.1 - 3.4e-24 85.8 0.1 3.6e-22 79.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 CAR25195.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Hexokinase GCR1_C PF12550.8 CAR25196.1 - 1.8e-10 41.0 0.1 3.3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Cep57_CLD_2 PF14197.6 CAR25196.1 - 0.0038 17.3 1.7 0.0093 16.0 1.7 1.6 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Mod_r PF07200.13 CAR25196.1 - 0.04 14.0 0.3 0.094 12.8 0.3 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 CAR25196.1 - 0.076 13.5 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_1 PF00170.21 CAR25196.1 - 0.094 12.8 1.3 0.24 11.5 1.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor XRCC4 PF06632.12 CAR25196.1 - 0.098 11.5 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DivIC PF04977.15 CAR25196.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Septum formation initiator IFP_35_N PF07334.13 CAR25196.1 - 0.13 12.3 0.1 0.62 10.2 0.0 2.2 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Rax2 PF12768.7 CAR25197.1 - 3.5e-51 173.7 12.1 7.2e-51 172.7 0.4 3.8 3 0 0 3 3 3 2 Cortical protein marker for cell polarity Kelch_4 PF13418.6 CAR25197.1 - 0.26 11.3 1.7 24 5.0 0.1 4.3 4 0 0 4 4 4 0 Galactose oxidase, central domain TRAPPC-Trs85 PF12739.7 CAR25198.1 - 3.3e-107 359.0 4.1 4.6e-107 358.5 4.1 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.16 CAR25199.1 - 3.4e-197 656.2 5.7 5.4e-197 655.6 5.7 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2205 PF10224.9 CAR25200.1 - 1e-09 38.2 4.1 1e-09 38.2 4.1 1.4 1 1 0 1 1 1 1 Short coiled-coil protein CCDC106 PF15794.5 CAR25200.1 - 0.015 15.0 1.2 0.015 15.0 1.2 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 RBD-FIP PF09457.10 CAR25200.1 - 0.045 13.7 5.0 1.2 9.2 5.0 2.3 1 1 0 1 1 1 0 FIP domain DUF5094 PF17015.5 CAR25200.1 - 0.061 13.4 4.2 0.063 13.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) PXA PF02194.15 CAR25200.1 - 0.082 12.9 1.4 0.099 12.6 1.4 1.1 1 0 0 1 1 1 0 PXA domain Actin PF00022.19 CAR25202.1 - 1.4e-14 53.5 0.2 1.8e-10 40.0 0.1 2.6 1 1 2 3 3 3 2 Actin Actin_micro PF17003.5 CAR25202.1 - 0.033 13.4 0.2 0.045 12.9 0.2 1.2 1 0 0 1 1 1 0 Putative actin-like family Serinc PF03348.15 CAR25203.1 - 1.3e-132 442.8 13.1 1.4e-132 442.7 13.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1689 PF07954.11 CAR25203.1 - 0.37 11.2 2.3 8.4 6.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1689) Rad51 PF08423.11 CAR25204.1 - 6.9e-112 372.8 0.0 1.1e-111 372.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CAR25204.1 - 9.6e-10 38.4 0.1 1.4e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CAR25204.1 - 1.9e-06 27.4 0.1 5.8e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CAR25204.1 - 2.7e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CAR25204.1 - 3.9e-05 24.2 0.5 8.9e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.11 CAR25204.1 - 0.022 13.9 0.0 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 PAXNEB protein Peptidase_M24 PF00557.24 CAR25205.1 - 3.3e-06 27.0 0.0 7.7e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Metallopeptidase family M24 E1_dh PF00676.20 CAR25206.1 - 1.2e-120 402.0 0.3 1.4e-120 401.7 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CAR25206.1 - 0.024 13.9 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 CAR25206.1 - 0.056 14.4 3.0 0.34 11.9 0.1 3.0 2 2 0 2 2 2 0 KRTAP type 7 family Ste5_C PF12194.8 CAR25207.1 - 3.8e-71 239.0 0.0 6.8e-71 238.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase Fus3-binding Zn_ribbon_17 PF17120.5 CAR25207.1 - 0.056 13.1 2.7 0.12 12.0 2.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CAR25207.1 - 0.09 12.8 6.1 0.28 11.2 6.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR25207.1 - 0.2 11.6 8.6 0.063 13.2 5.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR25207.1 - 0.23 11.8 8.5 0.09 13.1 5.3 2.1 2 0 0 2 2 2 0 Ring finger domain zf-RING_11 PF17123.5 CAR25207.1 - 7.1 6.5 8.6 1.7 8.4 4.4 2.1 2 0 0 2 2 2 0 RING-like zinc finger PH_4 PF15404.6 CAR25208.1 - 6e-77 257.6 0.1 1.6e-76 256.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 CAR25208.1 - 3e-24 84.4 0.7 8.4e-24 83.0 0.2 2.2 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 CAR25208.1 - 9.7e-07 29.3 3.3 0.45 11.0 0.1 5.3 4 1 0 4 4 4 2 PH domain PH_9 PF15410.6 CAR25208.1 - 0.04 14.3 0.0 22 5.4 0.0 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain DUF262 PF03235.14 CAR25208.1 - 0.099 12.8 0.6 1.1 9.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF262 COPI_assoc PF08507.10 CAR25209.1 - 3.2e-40 137.2 6.1 3.5e-40 137.0 6.1 1.0 1 0 0 1 1 1 1 COPI associated protein DuoxA PF10204.9 CAR25209.1 - 0.22 10.5 4.8 0.13 11.3 3.0 1.5 1 1 0 1 1 1 0 Dual oxidase maturation factor DUF2892 PF11127.8 CAR25209.1 - 5.7 7.1 9.5 13 5.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) 14-3-3 PF00244.20 CAR25210.1 - 1.1e-107 358.5 3.9 1.3e-107 358.4 3.9 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CAR25210.1 - 0.0058 16.6 0.1 0.015 15.3 0.1 1.7 1 0 0 1 1 1 1 Flagellar protein FlaF AAA_12 PF13087.6 CAR25211.1 - 1.8e-60 204.0 0.0 3.7e-60 203.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR25211.1 - 1.3e-35 123.5 11.7 1.6e-18 67.5 0.1 3.3 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 CAR25211.1 - 2.2e-11 44.3 0.0 6.2e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR25211.1 - 8.8e-10 38.6 0.0 1.5e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CAR25211.1 - 1.2e-05 25.4 0.1 6.1e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CAR25211.1 - 1.8e-05 24.6 0.0 0.93 9.2 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CAR25211.1 - 0.00036 20.2 2.7 0.00055 19.6 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 CAR25211.1 - 0.0012 19.1 0.0 0.004 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CAR25211.1 - 0.0071 16.1 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DEAD PF00270.29 CAR25211.1 - 0.0074 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA PF00004.29 CAR25211.1 - 0.009 16.4 0.1 0.032 14.7 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR25211.1 - 0.01 16.3 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 CAR25211.1 - 0.011 15.6 0.1 0.011 15.6 0.1 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CAR25211.1 - 0.014 14.9 0.0 0.035 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CAR25211.1 - 0.015 14.8 0.0 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein RsgA_GTPase PF03193.16 CAR25211.1 - 0.039 13.9 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF1151 PF06625.11 CAR25211.1 - 0.04 13.8 2.0 0.096 12.6 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) T2SSE PF00437.20 CAR25211.1 - 0.09 11.8 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 CAR25211.1 - 0.1 11.8 1.0 1.6 7.9 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CAR25211.1 - 0.11 13.0 0.0 0.84 10.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 CAR25211.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Methyltransf_25 PF13649.6 CAR25212.1 - 2.1e-16 60.4 0.0 3.3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR25212.1 - 6.2e-16 58.8 0.0 9.6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR25212.1 - 6.6e-12 46.0 0.0 1e-11 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR25212.1 - 3.4e-09 36.7 0.0 4.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR25212.1 - 2.9e-08 33.3 0.0 4.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CAR25212.1 - 2e-07 31.0 0.0 2.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAR25212.1 - 0.00011 21.8 0.0 0.00028 20.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CAR25212.1 - 0.0084 15.5 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CAR25212.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CAR25212.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 CAR25212.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glutaredoxin PF00462.24 CAR25213.1 - 3.7e-18 65.5 0.3 1.1e-16 60.8 0.0 2.8 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 CAR25213.1 - 4.6e-14 52.3 0.1 8.5e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAR25213.1 - 7.7e-07 29.4 0.1 0.00012 22.4 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CAR25213.1 - 7.7e-07 29.1 0.0 1.7e-06 27.9 0.1 1.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CAR25213.1 - 0.00017 22.0 0.1 0.0027 18.2 0.0 2.7 2 2 1 3 3 3 1 Thioredoxin-like domain Redoxin PF08534.10 CAR25213.1 - 0.021 14.6 0.1 0.039 13.7 0.1 1.4 1 1 0 1 1 1 0 Redoxin TraF PF13728.6 CAR25213.1 - 0.044 13.6 0.0 9.5 6.0 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CAR25213.1 - 0.058 13.6 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 CAR25213.1 - 0.06 12.7 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Rad17 PF03215.15 CAR25214.1 - 4.7e-35 121.2 0.0 1.2e-34 119.9 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CAR25214.1 - 9.7e-05 22.8 0.0 0.00023 21.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 CAR25214.1 - 0.0023 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CAR25214.1 - 0.0072 16.6 0.0 0.019 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain CDC37_C PF08564.10 CAR25214.1 - 0.049 13.7 0.0 0.83 9.8 0.0 2.4 2 0 0 2 2 2 0 Cdc37 C terminal domain RNA_helicase PF00910.22 CAR25214.1 - 0.062 13.7 0.0 0.21 12.0 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Peptidase_S24 PF00717.23 CAR25214.1 - 0.071 13.1 0.0 3 7.9 0.0 2.7 2 0 0 2 2 2 0 Peptidase S24-like RuvB_N PF05496.12 CAR25214.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 CAR25214.1 - 0.15 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sec63 PF02889.16 CAR25215.1 - 1.2e-138 460.5 7.3 2.2e-78 263.0 0.8 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CAR25215.1 - 1.5e-39 135.6 0.0 3.1e-26 92.2 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CAR25215.1 - 1.2e-20 74.2 0.0 3.1e-12 46.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 CAR25215.1 - 3.9e-18 65.6 1.4 8e-18 64.6 0.1 2.3 2 0 0 2 2 2 1 N-terminal helicase PWI domain Helicase_C PF00271.31 CAR25215.1 - 1.2e-11 44.9 0.0 2.4e-06 27.8 0.0 4.3 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CAR25215.1 - 0.00038 20.7 0.6 0.14 12.4 0.1 3.5 2 1 0 2 2 2 1 AAA domain PYRIN PF02758.16 CAR25215.1 - 0.024 14.8 0.2 1.8 8.8 0.0 3.4 3 0 0 3 3 3 0 PAAD/DAPIN/Pyrin domain DEAD_2 PF06733.15 CAR25216.1 - 1.8e-55 187.3 2.5 3.1e-55 186.5 2.5 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CAR25216.1 - 9.8e-44 149.5 0.0 3.3e-43 147.8 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 CAR25216.1 - 3.3e-41 141.1 3.5 3.4e-38 131.3 0.3 2.7 3 0 0 3 3 3 2 Helical and beta-bridge domain ResIII PF04851.15 CAR25216.1 - 0.00045 20.3 2.5 0.0038 17.2 0.1 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR25216.1 - 0.0037 17.1 0.1 0.95 9.2 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR25216.1 - 0.025 14.9 1.1 5.1 7.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 CAR25216.1 - 0.026 13.8 0.1 1.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CAR25216.1 - 0.032 13.7 0.1 0.91 8.9 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 CAR25216.1 - 0.033 12.9 0.1 0.65 8.7 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain YtxC PF08812.11 CAR25216.1 - 0.098 12.3 1.3 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 YtxC-like family AAA_25 PF13481.6 CAR25216.1 - 0.18 11.4 0.0 0.45 10.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain ADK PF00406.22 CAR25217.1 - 4.4e-40 137.2 0.0 5.2e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAR25217.1 - 6.6e-17 62.2 0.0 9.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CAR25217.1 - 5.2e-15 55.1 0.1 8.2e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CAR25217.1 - 0.00035 20.7 0.0 0.00095 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR25217.1 - 0.00086 19.8 0.0 0.0035 17.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain RRM_1 PF00076.22 CAR25218.1 - 1.8e-82 271.1 8.3 5.5e-20 71.0 0.1 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CAR25218.1 - 2e-17 63.1 3.0 7.5e-17 61.3 0.1 3.0 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CAR25218.1 - 2.5e-10 40.0 0.0 0.047 13.3 0.0 4.2 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CAR25218.1 - 5.4e-06 26.4 7.2 0.39 10.8 0.8 5.1 5 0 0 5 5 5 2 RNA binding motif RRM_occluded PF16842.5 CAR25218.1 - 0.00043 20.1 0.0 0.034 14.0 0.0 3.0 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CAR25218.1 - 0.00045 20.3 0.8 2.8 8.1 0.0 4.8 4 4 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CAR25218.1 - 0.0022 18.0 1.2 10 6.2 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 CAR25218.1 - 0.0023 17.8 0.0 2.2 8.1 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF4523) PNPase PF03726.14 CAR25218.1 - 0.0071 16.8 0.7 0.04 14.4 0.1 2.6 2 0 0 2 2 2 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4572 PF15139.6 CAR25218.1 - 0.048 13.6 0.1 2.1 8.2 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4572) CPSF_A PF03178.15 CAR25218.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 CPSF A subunit region OB_RNB PF08206.11 CAR25218.1 - 0.11 12.2 1.5 57 3.5 0.0 3.5 3 0 0 3 3 3 0 Ribonuclease B OB domain GIY-YIG PF01541.24 CAR25218.1 - 0.12 12.6 0.7 5.8 7.3 0.1 2.8 2 0 0 2 2 2 0 GIY-YIG catalytic domain BBE PF08031.12 CAR25218.1 - 0.16 12.1 0.2 4.4 7.5 0.1 2.7 2 0 0 2 2 2 0 Berberine and berberine like DUF1825 PF08855.10 CAR25218.1 - 0.18 11.8 1.7 8 6.5 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Bac_DNA_binding PF00216.21 CAR25218.1 - 0.33 11.2 2.9 5.2 7.4 0.1 3.3 3 0 0 3 3 3 0 Bacterial DNA-binding protein UQ_con PF00179.26 CAR25219.1 - 2.7e-47 159.9 0.0 3e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CAR25219.1 - 0.015 15.1 0.1 0.026 14.4 0.1 1.4 1 1 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 CAR25219.1 - 0.04 13.6 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CAR25219.1 - 0.12 12.6 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain PhoLip_ATPase_C PF16212.5 CAR25220.1 - 4e-78 262.6 27.3 4e-78 262.6 27.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR25220.1 - 3.3e-18 65.1 0.1 3.3e-18 65.1 0.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CAR25220.1 - 7.3e-12 45.2 0.0 3.8e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR25220.1 - 4.6e-10 40.1 2.8 7e-06 26.5 0.9 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CAR25220.1 - 0.00011 21.7 0.3 0.00054 19.5 0.0 2.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAR25220.1 - 0.0018 18.1 0.2 0.0041 16.9 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4131 PF13567.6 CAR25220.1 - 0.38 10.4 5.8 22 4.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FtsX PF02687.21 CAR25220.1 - 9 6.8 13.3 5.2 7.6 2.3 2.9 2 0 0 2 2 2 0 FtsX-like permease family DUF824 PF05688.11 CAR25221.1 - 0.13 12.1 0.1 0.43 10.4 0.1 1.9 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) PolyA_pol PF01743.20 CAR25222.1 - 6.9e-30 104.1 0.0 1.2e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CAR25222.1 - 3.7e-06 26.6 0.0 1.3e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 CAR25222.1 - 0.0067 16.4 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative JmjC PF02373.22 CAR25223.1 - 1.6e-39 134.9 0.6 1.6e-39 134.9 0.6 2.1 2 0 0 2 2 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CAR25223.1 - 3.9e-14 52.3 0.7 1.2e-13 50.7 0.7 2.0 1 0 0 1 1 1 1 jmjN domain zf-H2C2_2 PF13465.6 CAR25223.1 - 5.6e-07 29.7 11.8 1.3e-06 28.6 7.2 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CAR25223.1 - 2.8e-05 24.3 15.6 0.009 16.4 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR25223.1 - 0.00049 20.7 16.8 0.1 13.5 5.2 3.3 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAR25223.1 - 0.0025 17.8 5.1 0.0025 17.8 5.1 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CAR25223.1 - 0.0074 16.4 3.6 0.0074 16.4 3.6 2.2 2 0 0 2 2 2 1 Zinc ribbon domain DZR PF12773.7 CAR25223.1 - 0.09 12.8 0.7 0.22 11.6 0.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-MYST PF17772.1 CAR25223.1 - 0.11 12.2 0.1 0.39 10.4 0.1 1.9 1 0 0 1 1 1 0 MYST family zinc finger domain zinc_ribbon_5 PF13719.6 CAR25223.1 - 0.63 9.8 3.9 0.41 10.5 1.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 CAR25223.1 - 2.2 8.7 7.7 0.8 10.1 1.9 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CAR25223.1 - 5.6 7.1 7.6 12 6.1 1.5 2.8 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.8 CAR25223.1 - 7.1 7.0 15.3 0.29 11.5 3.6 3.0 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 CAR25223.1 - 8.2 7.2 11.3 0.85 10.3 0.5 3.7 3 1 1 4 4 4 0 Protein of unknown function (FYDLN_acid) MutS_V PF00488.21 CAR25224.1 - 6.1e-64 215.5 0.4 1.4e-63 214.4 0.4 1.6 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 CAR25224.1 - 3.9e-33 114.1 0.0 7.4e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CAR25224.1 - 2.5e-32 112.7 0.0 5.4e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 CAR25224.1 - 1.3e-15 57.5 0.0 2.7e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CAR25224.1 - 2.3e-14 53.9 0.0 5.8e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 CAR25224.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNF2_N PF00176.23 CAR25225.1 - 1.2e-63 215.0 0.0 2e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 CAR25225.1 - 9.3e-46 155.1 2.9 9.3e-46 155.1 2.9 3.7 3 0 0 3 3 3 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 CAR25225.1 - 1.5e-26 92.7 2.1 1.5e-26 92.7 2.1 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.24 CAR25225.1 - 1.2e-22 79.5 2.8 4.4e-13 48.9 0.0 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CAR25225.1 - 6e-20 71.6 0.0 1.6e-19 70.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25225.1 - 7.8e-10 39.0 0.4 6.7e-09 36.0 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CAR25225.1 - 2.3e-08 33.5 0.1 1.2e-07 31.3 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CAR25225.1 - 0.00066 19.5 0.0 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.9 CAR25225.1 - 0.001 18.4 0.1 0.0032 16.7 0.1 1.9 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SLIDE PF09111.10 CAR25225.1 - 0.017 15.1 0.0 0.11 12.5 0.0 2.4 1 0 0 1 1 1 0 SLIDE CHDCT2 PF08074.11 CAR25225.1 - 0.053 13.7 0.0 0.49 10.5 0.0 2.7 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Myb_DNA-binding PF00249.31 CAR25225.1 - 0.095 12.9 0.0 0.37 11.0 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain ABC_tran PF00005.27 CAR25226.1 - 2.4e-34 118.8 0.0 1.8e-16 60.9 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 CAR25226.1 - 1.4e-14 53.6 6.4 4e-14 52.1 6.4 1.9 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 CAR25226.1 - 1.3e-10 41.6 5.2 0.15 11.9 0.6 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR25226.1 - 4.9e-09 35.9 1.5 0.022 14.2 0.1 3.9 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 CAR25226.1 - 2.1e-08 33.6 3.0 2.1e-08 33.6 3.0 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 CAR25226.1 - 3.5e-06 26.8 14.1 9.3e-06 25.5 3.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 CAR25226.1 - 5.4e-06 26.9 0.0 0.0074 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CAR25226.1 - 1.2e-05 25.3 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Fer4_10 PF13237.6 CAR25226.1 - 2.3e-05 24.4 8.9 0.00063 19.8 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA PF00004.29 CAR25226.1 - 2.9e-05 24.5 0.0 0.12 12.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CAR25226.1 - 7.6e-05 22.6 0.1 0.25 11.0 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CAR25226.1 - 0.00014 21.5 0.6 0.47 10.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CAR25226.1 - 0.00017 21.9 0.0 0.054 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CAR25226.1 - 0.00032 21.3 0.0 0.048 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 CAR25226.1 - 0.00033 20.7 12.6 0.00087 19.4 12.6 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 CAR25226.1 - 0.00072 19.5 0.8 0.00072 19.5 0.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_30 PF13604.6 CAR25226.1 - 0.0013 18.5 0.3 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_7 PF12838.7 CAR25226.1 - 0.0015 19.1 0.7 0.0015 19.1 0.7 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.15 CAR25226.1 - 0.0023 17.9 0.2 0.41 10.5 0.0 2.7 2 1 1 3 3 3 1 Rad17 P-loop domain Fer4_9 PF13187.6 CAR25226.1 - 0.0046 17.1 12.0 0.0095 16.1 12.0 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 CAR25226.1 - 0.0066 16.2 0.6 1.3 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR25226.1 - 0.0084 16.3 0.0 2.6 8.2 0.0 2.7 3 0 0 3 3 2 1 AAA domain Fer4_16 PF13484.6 CAR25226.1 - 0.012 16.6 0.2 0.012 16.6 0.2 2.7 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain SRP54 PF00448.22 CAR25226.1 - 0.012 15.3 1.9 0.96 9.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CAR25226.1 - 0.013 15.4 1.3 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CAR25226.1 - 0.013 15.7 0.0 7.2 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CAR25226.1 - 0.014 15.4 1.0 0.13 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CAR25226.1 - 0.016 15.6 0.0 4.9 7.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 CAR25226.1 - 0.022 13.9 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 CAR25226.1 - 0.031 14.4 0.0 7.1 6.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CAR25226.1 - 0.038 13.5 0.3 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 CAR25226.1 - 0.044 13.8 0.0 0.61 10.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE VirE PF05272.11 CAR25226.1 - 0.077 12.7 0.0 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_14 PF13173.6 CAR25226.1 - 0.1 12.6 0.1 23 5.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 CAR25226.1 - 0.12 13.0 0.0 6 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 CAR25226.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_13 PF13166.6 CAR25226.1 - 0.15 10.7 0.1 0.41 9.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 CAR25226.1 - 0.18 10.6 0.0 0.37 9.6 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Fer4_4 PF12800.7 CAR25226.1 - 0.46 11.1 14.6 0.14 12.7 2.7 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain ChaC PF04752.12 CAR25227.1 - 9.1e-54 182.2 0.0 1.1e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Rad4 PF03835.15 CAR25228.1 - 2.5e-36 124.6 3.1 6e-36 123.3 3.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CAR25228.1 - 2e-25 89.0 0.1 3.8e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CAR25228.1 - 1.9e-16 59.6 0.0 4.8e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 CAR25228.1 - 4.1e-08 33.7 0.0 1.7e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily BHD_2 PF10404.9 CAR25228.1 - 6.9e-05 23.7 0.1 6.9e-05 23.7 0.1 4.0 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 DUF1411 PF07199.11 CAR25228.1 - 0.067 12.9 0.3 0.2 11.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1411) SPT2 PF08243.11 CAR25229.1 - 2.8e-27 95.4 25.0 2.8e-27 95.4 25.0 2.0 2 1 1 3 3 3 1 SPT2 chromatin protein DUF5636 PF18686.1 CAR25229.1 - 2.2 8.4 6.8 1.7 8.8 0.7 2.7 1 1 2 3 3 3 0 Family of unknown function (DUF5636) SPX PF03105.19 CAR25230.1 - 3.7e-07 30.4 0.1 3.7e-07 30.4 0.1 3.5 2 2 1 3 3 3 1 SPX domain SKA2 PF16740.5 CAR25230.1 - 0.047 13.5 1.3 0.099 12.4 1.3 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 TssN PF17555.2 CAR25230.1 - 4.6 6.5 6.7 8 5.8 6.7 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN Slu7 PF11708.8 CAR25231.1 - 1.6e-20 74.0 16.5 2.3e-19 70.2 16.5 2.6 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 CAR25231.1 - 0.0034 17.4 0.9 0.0059 16.6 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle DNA_ligase_OB_2 PF14743.6 CAR25231.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase OB-like domain Nop52 PF05997.12 CAR25232.1 - 2.5e-73 246.4 4.3 2.9e-73 246.2 4.3 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 CAR25232.1 - 0.011 15.9 0.3 0.03 14.4 0.1 1.8 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair SecE PF00584.20 CAR25233.1 - 1.3e-11 44.2 0.1 1.4e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coiled-coil_56 PF09813.9 CAR25233.1 - 0.063 13.3 0.0 0.071 13.2 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 CBFD_NFYB_HMF PF00808.23 CAR25234.1 - 5.4e-10 39.4 0.1 8.6e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SSF PF00474.17 CAR25235.1 - 2.2e-06 26.8 31.9 8.5e-06 24.9 31.9 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family MRFAP1 PF15155.6 CAR25236.1 - 0.17 12.4 0.1 0.44 11.1 0.1 1.6 1 0 0 1 1 1 0 MORF4 family-associated protein1 Cwf_Cwc_15 PF04889.12 CAR25236.1 - 2.5 7.8 9.3 0.063 13.0 2.2 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Secretin_N_2 PF07655.13 CAR25236.1 - 4.2 8.0 24.3 6.3 7.4 15.2 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain DUF846 PF05832.12 CAR25237.1 - 1.5e-47 161.1 4.1 1.8e-47 160.8 4.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Methyltransf_8 PF05148.15 CAR25238.1 - 1.3e-65 221.3 1.9 1.2e-63 214.9 0.3 2.5 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CAR25238.1 - 1.6e-07 31.8 0.0 7.4e-07 29.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR25238.1 - 1.2e-05 26.0 0.0 0.00012 22.7 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR25238.1 - 0.0028 17.4 3.0 0.017 14.9 0.1 3.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CAR25238.1 - 0.021 14.4 0.0 0.58 9.7 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CAR25238.1 - 2.2 8.3 0.0 2.2 8.3 0.0 3.0 3 1 0 3 3 3 0 Methyltransferase domain GREB1 PF15782.5 CAR25238.1 - 2.2 5.3 4.8 54 0.7 7.2 1.8 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer ATP_sub_h PF10775.9 CAR25239.1 - 8.3e-27 93.0 0.6 8.3e-27 93.0 0.6 1.5 2 0 0 2 2 2 1 ATP synthase complex subunit h ADIP PF11559.8 CAR25240.1 - 0.00048 20.2 1.4 0.0028 17.7 0.0 2.4 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Ras PF00071.22 CAR25241.1 - 1.4e-50 171.1 0.0 1.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR25241.1 - 2.5e-30 105.2 0.1 6.6e-30 103.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR25241.1 - 2.4e-11 43.4 0.0 3.3e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 CAR25241.1 - 0.00082 19.7 0.1 0.0068 16.8 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CAR25241.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAR25241.1 - 0.0022 17.4 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR25241.1 - 0.017 14.7 0.3 0.079 12.5 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CAR25241.1 - 0.018 14.2 2.1 2.1 7.4 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 CAR25241.1 - 0.02 14.7 0.2 0.033 13.9 0.2 1.4 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CAR25241.1 - 0.02 14.3 0.1 0.039 13.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ATPase PF06745.13 CAR25241.1 - 0.026 13.9 0.2 0.039 13.3 0.2 1.2 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 CAR25241.1 - 0.027 14.4 0.1 8.5 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 CAR25241.1 - 0.03 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 CAR25241.1 - 0.042 13.3 0.0 0.069 12.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 CAR25241.1 - 0.11 12.7 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CAR25241.1 - 0.11 12.5 0.1 0.29 11.2 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CAR25241.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CAR25241.1 - 0.14 11.5 0.3 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin TPR_1 PF00515.28 CAR25242.1 - 7.6e-06 25.5 1.9 0.0064 16.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR25242.1 - 1.1e-05 25.1 0.9 0.0008 19.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR25242.1 - 0.00038 20.5 0.3 0.005 17.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR25242.1 - 0.0039 17.2 0.9 0.01 15.9 0.1 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 CAR25242.1 - 0.0064 17.2 0.2 0.047 14.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR25242.1 - 0.007 16.8 2.1 0.015 15.8 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR25242.1 - 0.032 13.9 0.5 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 TPR repeat DUF1525 PF07511.11 CAR25242.1 - 0.11 12.6 1.0 1.1 9.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) IF-2B PF01008.17 CAR25243.1 - 1.7e-81 273.5 0.1 2.5e-81 273.0 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Epimerase PF01370.21 CAR25244.1 - 1.1e-07 31.5 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CAR25244.1 - 1.7e-07 31.3 0.0 1.1e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CAR25244.1 - 1.9e-05 23.8 0.0 0.00011 21.4 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 CAR25244.1 - 5.5e-05 22.7 0.0 8.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR25244.1 - 0.00027 20.9 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 CAR25244.1 - 0.00029 20.1 0.0 0.078 12.1 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CAR25244.1 - 0.00058 19.1 0.0 0.0023 17.1 0.0 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CAR25244.1 - 0.0025 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CAR25244.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family GTP_EFTU PF00009.27 CAR25245.1 - 6e-50 169.5 0.1 1.4e-49 168.3 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CAR25245.1 - 1e-41 141.4 9.1 2.2e-41 140.3 9.1 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CAR25245.1 - 1.2e-19 70.1 0.0 3.1e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR25245.1 - 3.4e-07 30.6 3.0 5.8e-07 29.8 2.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR25245.1 - 5.1e-06 26.5 0.4 2.2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 CAR25245.1 - 1.4e-05 24.7 0.5 6.8e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Ras family RF3_C PF16658.5 CAR25245.1 - 0.00046 20.0 0.0 0.0063 16.3 0.0 2.3 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CAR25245.1 - 0.0078 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.10 CAR25245.1 - 0.011 15.2 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Roc PF08477.13 CAR25245.1 - 0.022 15.0 0.1 0.16 12.1 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Hus1 PF04005.12 CAR25246.1 - 1e-20 74.0 0.1 4.3e-20 72.0 0.1 1.8 1 1 0 1 1 1 1 Hus1-like protein Aminotran_5 PF00266.19 CAR25247.1 - 6.1e-36 124.1 0.0 7.4e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_S30 PF04758.14 CAR25248.1 - 8.1e-30 102.8 6.2 8.8e-30 102.7 6.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GCIP PF13324.6 CAR25249.1 - 2.7e-54 184.5 0.6 3.2e-54 184.3 0.6 1.1 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DASH_Dam1 PF08653.10 CAR25249.1 - 3.3 7.6 4.7 31 4.5 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Dam1 WH1 PF00568.23 CAR25250.1 - 5.9e-32 109.9 0.0 8.3e-32 109.4 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CAR25250.1 - 1.4e-05 24.7 1.5 2.7e-05 23.9 1.5 1.5 1 0 0 1 1 1 1 WH2 motif Glyco_hydro_18 PF00704.28 CAR25251.1 - 6.4e-31 108.2 1.6 6.4e-31 108.2 1.6 2.1 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CAR25251.1 - 5.6e-08 32.6 3.1 5.6e-08 32.6 3.1 5.8 4 2 3 7 7 7 1 Carbohydrate binding domain (family 19) DUF2793 PF10983.8 CAR25251.1 - 0.032 14.1 0.3 0.29 11.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2793) Methyltransf_16 PF10294.9 CAR25252.1 - 7.9e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CAR25252.1 - 0.003 17.4 0.0 0.0041 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ECH_1 PF00378.20 CAR25253.1 - 1.6e-12 47.2 0.0 4.2e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAR25253.1 - 2.6e-08 33.7 0.0 4.6e-08 32.9 0.0 1.4 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF1640 PF07798.11 CAR25254.1 - 7.8e-22 78.2 0.9 1.1e-21 77.6 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) RF-1 PF00472.20 CAR25255.1 - 2.2e-20 72.7 3.7 3.3e-20 72.2 3.7 1.3 1 0 0 1 1 1 1 RF-1 domain Fungal_trans PF04082.18 CAR25256.1 - 5.9e-20 71.4 6.2 5.9e-20 71.4 6.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR25256.1 - 0.00016 21.7 11.0 0.00016 21.7 11.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSF73-100_C PF11718.8 CAR25257.1 - 2e-58 197.5 0.7 3.3e-58 196.8 0.7 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CAR25257.1 - 4.1e-29 101.1 0.0 8.6e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 CAR25257.1 - 2.1e-22 80.1 0.8 3.8e-22 79.3 0.8 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CAR25257.1 - 8.1e-20 71.1 0.0 1.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CAR25257.1 - 4.1e-18 65.1 0.1 1.2e-17 63.6 0.0 1.8 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CAR25257.1 - 8.9e-07 28.6 0.4 2.6e-05 23.8 0.2 2.5 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CAR25257.1 - 5.8e-05 23.0 0.1 0.00032 20.6 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CAR25257.1 - 0.0065 15.7 0.0 0.015 14.5 0.0 1.6 1 0 0 1 1 1 1 Putative beta-lactamase-like family DEAD PF00270.29 CAR25258.1 - 2.7e-38 131.5 1.7 5.1e-38 130.6 1.7 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR25258.1 - 6.7e-31 106.9 1.1 3.2e-30 104.7 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25258.1 - 1.4e-06 28.4 0.0 5e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaI_N PF07319.11 CAR25258.1 - 0.079 13.6 3.0 9.6 7.0 0.3 3.2 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus LSM PF01423.22 CAR25259.1 - 2.2e-17 62.5 0.5 2.9e-17 62.1 0.5 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CAR25259.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein MCM PF00493.23 CAR25260.1 - 2.5e-104 347.2 0.0 3.8e-104 346.7 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR25260.1 - 5.9e-34 116.6 0.0 1e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAR25260.1 - 1e-27 96.3 1.4 2.6e-27 95.1 1.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAR25260.1 - 3.8e-15 56.3 0.0 9.6e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR25260.1 - 3.4e-06 26.6 0.0 0.00055 19.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAR25260.1 - 4.2e-06 26.8 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CAR25260.1 - 0.00016 21.5 0.0 0.0019 18.0 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAR25260.1 - 0.032 13.9 0.0 0.95 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain CBM_21 PF03370.13 CAR25262.1 - 5.7e-26 90.9 2.3 1e-25 90.1 2.3 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CAR25262.1 - 1.1e-05 26.0 5.7 5.7e-05 23.6 5.7 2.1 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Lebercilin PF15619.6 CAR25263.1 - 0.013 15.2 8.4 0.013 15.2 8.4 4.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.15 CAR25263.1 - 3 8.2 48.5 0.21 12.1 21.5 3.3 1 1 2 3 3 3 0 Fez1 DUF3584 PF12128.8 CAR25263.1 - 3.3 5.1 47.8 0.058 10.9 31.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 CAR25263.1 - 3.6 7.6 28.4 0.18 11.9 4.1 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CAR25263.1 - 4.4 7.5 40.6 0.26 11.4 8.1 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 CAR25263.1 - 9.6 4.2 53.1 37 2.3 52.4 2.2 1 1 1 2 2 2 0 HOOK protein Cnd1 PF12717.7 CAR25264.1 - 3.4e-50 170.3 10.1 1.1e-44 152.3 0.1 3.9 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CAR25264.1 - 2.3e-45 154.4 0.0 9.1e-45 152.5 0.0 2.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 CAR25264.1 - 3.4e-11 42.4 5.1 0.16 12.3 0.1 5.8 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 CAR25264.1 - 1.1e-09 38.5 0.0 0.012 16.0 0.1 3.7 2 1 1 3 3 3 3 HEAT repeats Cnd3 PF12719.7 CAR25264.1 - 6.3e-07 28.9 4.5 1.1e-05 24.7 0.9 3.1 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 CAR25264.1 - 2.5e-06 27.8 0.9 7.5 7.2 0.0 5.2 4 0 0 4 4 4 2 HEAT-like repeat RTP1_C1 PF10363.9 CAR25264.1 - 0.0058 16.8 1.3 1.6 8.9 0.1 3.7 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vpu PF00558.19 CAR25264.1 - 0.14 11.9 7.8 9.5 6.1 2.8 4.3 4 0 0 4 4 4 0 Vpu protein DUF2120 PF09893.9 CAR25264.1 - 0.5 10.5 2.4 0.77 9.9 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Ferrochelatase PF00762.19 CAR25265.1 - 1.6e-96 323.1 0.0 1.8e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MBOAT PF03062.19 CAR25266.1 - 3.1e-63 214.2 12.2 3.1e-63 214.2 12.2 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CALCOCO1 PF07888.11 CAR25266.1 - 0.085 11.7 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Med4 PF10018.9 CAR25267.1 - 4.6e-33 114.5 3.6 6.2e-33 114.1 3.6 1.1 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF4187 PF13821.6 CAR25268.1 - 5e-19 67.8 0.3 1.1e-18 66.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CAR25268.1 - 8e-07 28.9 2.0 1.4e-06 28.1 2.0 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CAR25268.1 - 0.075 13.1 0.7 0.21 11.7 0.7 1.7 1 0 0 1 1 1 0 G-patch domain zf-C2H2_6 PF13912.6 CAR25268.1 - 0.13 12.3 0.7 0.29 11.2 0.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR25268.1 - 0.15 12.4 1.2 0.31 11.4 1.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF1179 PF06678.11 CAR25268.1 - 0.35 10.9 2.5 0.89 9.6 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) DcpS_C PF11969.8 CAR25269.1 - 3.3e-35 121.0 0.0 6.4e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CAR25269.1 - 1.7e-34 118.8 0.0 2.7e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Longin PF13774.6 CAR25270.1 - 6.8e-19 67.7 0.1 1e-18 67.1 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CAR25270.1 - 3.4e-16 58.8 0.2 5.7e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.12 CAR25270.1 - 0.0099 15.9 1.1 0.0099 15.9 1.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) CCSMST1 PF15013.6 CAR25270.1 - 0.046 13.9 0.3 0.12 12.5 0.3 1.8 1 0 0 1 1 1 0 CCSMST1 family E1-E2_ATPase PF00122.20 CAR25270.1 - 0.092 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 E1-E2 ATPase Pyrid_oxidase_2 PF13883.6 CAR25271.1 - 7.3e-40 136.7 0.6 1.4e-39 135.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase YAcAr PF10686.9 CAR25271.1 - 0.51 10.3 4.5 21 5.2 0.4 3.4 2 1 1 3 3 3 0 YspA, cpYpsA-related SLOG family MFAP1 PF06991.11 CAR25272.1 - 1.1e-08 35.2 15.4 1.1e-08 35.2 15.4 1.8 1 1 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing MRP-S27 PF10037.9 CAR25272.1 - 0.027 13.3 8.3 0.038 12.9 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 RibD_C PF01872.17 CAR25273.1 - 3.6e-33 115.1 0.0 4.1e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain RNA_pol_Rpb5_C PF01191.19 CAR25274.1 - 6e-33 112.5 0.9 1.2e-32 111.5 0.4 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CAR25274.1 - 4.6e-29 100.8 0.2 9.6e-29 99.8 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 CAR25274.1 - 0.027 14.7 0.3 0.054 13.8 0.3 1.4 1 0 0 1 1 1 0 Sof1-like domain SH3_2 PF07653.17 CAR25274.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Mrr_cat PF04471.12 CAR25274.1 - 0.15 12.1 0.0 0.57 10.2 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease DUF3337 PF11816.8 CAR25275.1 - 2.1e-29 102.6 0.2 5.2e-29 101.3 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) RAWUL PF16207.5 CAR25275.1 - 0.09 13.5 0.1 0.21 12.3 0.1 1.6 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like WD40 PF00400.32 CAR25275.1 - 3.2 8.8 8.2 8.1 7.5 0.2 4.7 5 1 0 5 5 5 0 WD domain, G-beta repeat CENP-S PF15630.6 CAR25276.1 - 4.5e-24 84.6 0.0 6.4e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CAR25276.1 - 9.9e-07 28.9 0.1 2.8e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Ribosomal_S9 PF00380.19 CAR25277.1 - 5.3e-41 139.9 1.6 5.7e-41 139.8 0.7 1.5 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Pox_VLTF3 PF04947.14 CAR25277.1 - 0.061 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like ADH_N PF08240.12 CAR25278.1 - 7.7e-30 103.0 0.6 2e-29 101.7 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR25278.1 - 2.9e-26 92.0 0.7 4.6e-26 91.3 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR25278.1 - 4.9e-05 24.4 0.0 8.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 CAR25278.1 - 0.14 11.6 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gp_dh_C PF02800.20 CAR25280.1 - 4.1e-71 237.7 0.1 6.7e-71 237.0 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CAR25280.1 - 4.4e-39 132.9 0.0 1.1e-38 131.6 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CAR25280.1 - 0.076 12.4 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 CAR25280.1 - 0.1 12.7 0.7 0.38 10.9 0.1 2.4 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RSN1_7TM PF02714.15 CAR25281.1 - 1.9e-87 293.0 24.7 1.9e-87 293.0 24.7 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR25281.1 - 4.2e-43 146.8 2.9 2.2e-42 144.5 1.6 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CAR25281.1 - 6.6e-26 91.6 0.2 1.2e-25 90.8 0.2 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CAR25281.1 - 2.2e-24 85.5 0.1 5.9e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MAP65_ASE1 PF03999.12 CAR25281.1 - 0.0072 15.1 0.5 0.011 14.4 0.5 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) BPD_transp_1 PF00528.22 CAR25281.1 - 0.0076 16.0 4.6 0.0076 16.0 4.6 3.3 4 1 0 4 4 4 1 Binding-protein-dependent transport system inner membrane component ZZ PF00569.17 CAR25282.1 - 1e-05 25.2 0.6 1e-05 25.2 0.6 2.8 3 0 0 3 3 3 1 Zinc finger, ZZ type ATG19_autophagy PF12744.7 CAR25283.1 - 2.8e-91 305.1 0.5 4.5e-91 304.4 0.5 1.3 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding ZZ PF00569.17 CAR25283.1 - 6.1e-06 25.9 8.7 1.7e-05 24.6 3.0 2.5 1 1 1 2 2 2 2 Zinc finger, ZZ type DUF5638 PF18688.1 CAR25283.1 - 0.022 15.0 0.1 0.065 13.6 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5638) eRF1_2 PF03464.15 CAR25284.1 - 4.7e-46 156.4 0.1 9.4e-46 155.4 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 CAR25284.1 - 9.6e-40 135.6 0.2 1.8e-39 134.7 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CAR25284.1 - 4.4e-20 72.0 0.0 6.8e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CAR25284.1 - 6.5e-11 42.6 0.0 1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CAR25284.1 - 1.1e-08 35.4 0.0 1.9e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 Tnp_DNA_bind PF14706.6 CAR25284.1 - 0.031 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Transposase DNA-binding Ribosomal_L7Ae PF01248.26 CAR25284.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DEAD PF00270.29 CAR25285.1 - 1.1e-37 129.4 0.2 2.8e-37 128.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR25285.1 - 3.7e-30 104.5 0.1 4.5e-28 97.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25285.1 - 0.00016 21.7 0.5 0.0012 18.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UPF0524 PF15823.5 CAR25285.1 - 0.28 10.6 2.5 0.93 8.8 2.1 2.0 2 0 0 2 2 2 0 UPF0524 of C3orf70 SprA-related PF12118.8 CAR25285.1 - 8.5 5.4 13.6 0.81 8.8 7.8 2.0 2 0 0 2 2 2 0 SprA-related family Bmt2 PF11968.8 CAR25286.1 - 6.2e-80 268.2 0.1 7.9e-80 267.8 0.1 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CAR25286.1 - 0.0024 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RasGAP PF00616.19 CAR25287.1 - 9.3e-23 81.0 0.9 3.1e-15 56.4 0.4 3.7 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CAR25287.1 - 0.031 14.5 2.9 0.13 12.4 0.4 3.2 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain SCAPER_N PF16501.5 CAR25287.1 - 0.13 12.3 0.0 0.81 9.7 0.0 2.4 1 0 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum Pneumo_att_G PF05539.11 CAR25287.1 - 3.5 7.1 8.3 6.9 6.2 8.3 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G RNase_T PF00929.24 CAR25288.1 - 4.3e-15 56.6 0.0 1.2e-14 55.2 0.0 1.8 2 1 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CAR25288.1 - 0.022 14.5 0.0 0.071 12.8 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease CRIM PF16978.5 CAR25289.1 - 2e-36 125.2 0.8 2e-36 125.2 0.8 2.0 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CAR25289.1 - 5.4e-28 97.5 0.1 1.3e-27 96.2 0.1 1.7 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 CAR25289.1 - 0.0047 17.1 0.0 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 TUG ubiquitin-like domain CENP-B_dimeris PF09026.10 CAR25289.1 - 1.2 9.5 9.8 4.8 7.6 9.8 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_S10 PF00450.22 CAR25290.1 - 3.1e-128 428.8 0.2 3.6e-128 428.5 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase ATP19 PF11022.8 CAR25291.1 - 5.1e-24 84.4 0.0 5.7e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Brix PF04427.18 CAR25292.1 - 1.7e-41 142.5 0.1 2.3e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 Brix domain NatB_MDM20 PF09797.9 CAR25293.1 - 1.4e-49 169.1 4.3 1.4e-49 169.1 4.3 2.5 3 2 1 4 4 4 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 CAR25293.1 - 0.0042 17.6 0.1 12 6.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat SinI PF08671.10 CAR25293.1 - 0.0046 16.7 0.0 0.0094 15.7 0.0 1.5 1 0 0 1 1 1 1 Anti-repressor SinI TPR_14 PF13428.6 CAR25293.1 - 0.069 14.0 0.0 18 6.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Mannosyl_trans3 PF11051.8 CAR25294.1 - 1.7e-85 286.7 0.0 2.5e-85 286.1 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glutaredoxin PF00462.24 CAR25295.1 - 7.6e-13 48.5 0.0 1.3e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin zf-ANAPC11 PF12861.7 CAR25296.1 - 2.2e-41 139.8 4.8 3.4e-41 139.2 4.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CAR25296.1 - 3.7e-22 78.4 10.2 4.9e-22 78.0 10.2 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAR25296.1 - 6.4e-07 29.6 14.6 5.5e-06 26.6 14.6 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR25296.1 - 0.00012 21.8 5.5 0.00012 21.8 5.5 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CAR25296.1 - 0.0028 17.4 2.1 0.0028 17.4 2.1 2.8 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 CAR25296.1 - 0.003 17.5 12.0 0.012 15.6 12.3 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CAR25296.1 - 0.0043 17.0 9.0 0.092 12.8 7.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 CAR25296.1 - 0.0056 16.4 2.5 0.0056 16.4 2.5 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CAR25296.1 - 0.0079 16.3 2.7 0.0079 16.3 2.7 1.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CAR25296.1 - 0.013 15.3 6.9 0.013 15.3 6.9 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR25296.1 - 0.024 14.5 14.6 0.12 12.3 14.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 CAR25296.1 - 0.27 11.7 0.2 0.27 11.7 0.2 2.9 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain RINGv PF12906.7 CAR25296.1 - 0.67 10.1 8.7 1.9 8.7 8.7 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 CAR25296.1 - 0.93 9.7 17.8 25 5.1 17.8 3.1 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CAR25296.1 - 1.6 8.4 11.3 8.4 6.1 11.3 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 CAR25296.1 - 1.9 8.8 10.7 3.5 8.0 9.5 2.0 1 1 1 2 2 2 0 RING-like domain zf-HC5HC2H_2 PF13832.6 CAR25296.1 - 2.9 8.1 9.1 1.3 9.2 5.8 1.9 1 1 1 2 2 2 0 PHD-zinc-finger like domain DZR PF12773.7 CAR25296.1 - 2.9 8.0 10.5 7.3e+02 0.3 10.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon RecR PF02132.15 CAR25296.1 - 5.2 6.7 6.6 3.1 7.4 0.1 3.0 4 0 0 4 4 4 0 RecR protein zf-HC5HC2H PF13771.6 CAR25296.1 - 8.3 6.7 10.9 54 4.1 11.1 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain RCR PF12273.8 CAR25297.1 - 7.8e-32 110.4 2.6 7.8e-32 110.4 2.6 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF2207 PF09972.9 CAR25297.1 - 0.023 13.5 0.3 0.03 13.1 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Virul_fac_BrkB PF03631.15 CAR25297.1 - 0.026 14.1 0.7 0.033 13.8 0.7 1.1 1 0 0 1 1 1 0 Virulence factor BrkB SARAF PF06682.12 CAR25297.1 - 0.029 14.0 0.1 0.038 13.6 0.1 1.4 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis MIG-14_Wnt-bd PF06664.12 CAR25297.1 - 0.042 13.1 0.6 0.053 12.7 0.6 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Pox_EPC_I2-L1 PF12575.8 CAR25297.1 - 0.12 12.7 1.0 0.18 12.1 1.0 1.3 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF3328 PF11807.8 CAR25297.1 - 0.19 11.5 4.1 1.6 8.5 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) OATP PF03137.20 CAR25297.1 - 0.31 9.3 0.2 0.33 9.2 0.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SLC3A2_N PF16028.5 CAR25297.1 - 0.61 9.7 2.7 1.1 8.9 2.7 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus SNARE PF05739.19 CAR25297.1 - 4 7.5 8.2 6.3 6.9 8.2 1.3 1 0 0 1 1 1 0 SNARE domain EAGR_box PF16713.5 CAR25297.1 - 4 7.2 5.8 4.2 7.1 0.2 2.3 2 0 0 2 2 2 0 Enriched in aromatic and glycine Residues box Aldedh PF00171.22 CAR25298.1 - 7.5e-160 532.4 0.4 8.7e-160 532.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CAR25298.1 - 0.2 11.1 0.1 0.5 9.8 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Rad51 PF08423.11 CAR25299.1 - 5.3e-44 150.4 0.0 3.4e-38 131.4 0.0 2.3 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 CAR25299.1 - 1.7e-09 37.6 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CAR25299.1 - 0.0017 17.8 0.1 0.0041 16.5 0.1 1.8 1 1 0 1 1 1 1 KaiC RecA PF00154.21 CAR25299.1 - 0.01 15.3 0.5 0.052 13.0 0.5 2.0 1 1 0 1 1 1 0 recA bacterial DNA recombination protein NUP214 PF16755.5 CAR25299.1 - 0.044 13.0 0.5 0.078 12.2 0.5 1.3 1 0 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 CobU PF02283.16 CAR25299.1 - 0.06 12.9 0.2 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Capsid_N PF16903.5 CAR25299.1 - 0.086 12.5 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Major capsid protein N-terminus ATPase_2 PF01637.18 CAR25299.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CAR25299.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Maf1 PF09174.10 CAR25300.1 - 2e-45 155.1 5.8 2.1e-43 148.5 5.8 2.3 1 1 0 1 1 1 1 Maf1 regulator Sel1 PF08238.12 CAR25301.1 - 5e-10 39.7 4.0 0.00023 21.7 0.1 3.4 3 0 0 3 3 3 3 Sel1 repeat Tcp11 PF05794.13 CAR25302.1 - 1.6e-141 472.4 3.1 1.6e-141 472.4 3.1 1.8 2 0 0 2 2 2 1 T-complex protein 11 Spore_coat_CotO PF14153.6 CAR25302.1 - 0.00034 20.6 2.9 0.00081 19.4 2.9 1.7 1 0 0 1 1 1 1 Spore coat protein CotO DUF4834 PF16118.5 CAR25302.1 - 0.74 10.8 6.4 3.7 8.6 6.4 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) FlaG PF03646.15 CAR25302.1 - 2.6 8.3 9.6 12 6.1 9.6 2.1 1 0 0 1 1 1 0 FlaG protein CENP-T_C PF15511.6 CAR25303.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CAR25303.1 - 2.1e-05 24.9 0.1 2.5e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CAR25303.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CAR25303.1 - 3.6e-05 24.0 0.1 6.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CAR25303.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CAR25303.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAR25303.1 - 0.0067 16.4 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CAR25303.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CAR25304.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CAR25304.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CAR25304.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CAR25304.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAR25304.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CAR25304.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 CAR25305.1 - 7e-57 192.3 0.0 1.1e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase FMN_dh PF01070.18 CAR25305.1 - 0.099 11.6 0.1 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Pyrophosphatase PF00719.19 CAR25306.1 - 4.6e-58 195.6 0.1 6e-58 195.2 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase RCR PF12273.8 CAR25307.1 - 1.3e-23 83.9 0.5 2e-23 83.3 0.5 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Corona_nucleoca PF00937.18 CAR25307.1 - 0.025 13.6 0.4 0.036 13.1 0.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Mannosyl_trans2 PF04188.13 CAR25308.1 - 3e-87 293.8 34.2 3.9e-85 286.8 34.2 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) polyprenyl_synt PF00348.17 CAR25309.1 - 3.5e-67 226.1 0.0 8.5e-61 205.2 0.0 2.8 2 1 0 2 2 2 2 Polyprenyl synthetase Prenyltransf PF01255.19 CAR25310.1 - 6.1e-76 254.9 0.0 7.4e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ThiG PF05690.14 CAR25310.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Ran_BP1 PF00638.18 CAR25311.1 - 1.1e-53 180.6 0.8 1.8e-53 179.9 0.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CAR25311.1 - 0.00013 21.8 1.0 0.0018 18.2 1.0 2.1 1 1 0 1 1 1 1 WH1 domain DUF809 PF05663.11 CAR25311.1 - 8.1 6.6 10.7 11 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF809) Trehalase PF01204.18 CAR25312.1 - 4.1e-187 623.1 0.2 4.8e-187 622.8 0.2 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CAR25312.1 - 4.6e-16 58.2 2.1 7.9e-16 57.5 2.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain OCRE PF17780.1 CAR25312.1 - 0.33 11.0 2.1 0.31 11.1 0.3 1.9 2 0 0 2 2 2 0 OCRE domain Thiamine_BP PF01910.17 CAR25313.1 - 5.9e-29 99.8 0.1 6.7e-29 99.7 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein KDGP_aldolase PF07071.11 CAR25313.1 - 0.042 13.6 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 KDGP aldolase PAC4 PF16093.5 CAR25313.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Histone PF00125.24 CAR25314.1 - 2.3e-20 73.3 3.7 2.9e-20 73.0 3.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25314.1 - 7.4e-06 26.2 0.1 7.4e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CAR25314.1 - 0.002 18.6 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CAR25314.1 - 0.0086 16.3 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein YscO-like PF16789.5 CAR25314.1 - 0.05 13.6 0.5 0.06 13.4 0.5 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 CAR25315.1 - 1.2e-20 72.9 1.6 2e-20 72.2 1.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAR25315.1 - 3.1e-17 63.1 0.0 4.3e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25315.1 - 1.3e-05 25.3 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF155 PF02582.14 CAR25316.1 - 9.5e-56 188.7 0.7 1.4e-55 188.2 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CAR25316.1 - 0.11 13.0 0.2 0.26 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GAPES3 PF17154.4 CAR25316.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain HMG_box PF00505.19 CAR25317.1 - 3e-15 56.4 0.8 6.9e-15 55.2 0.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR25317.1 - 6.3e-14 52.3 1.0 1.1e-13 51.6 1.0 1.4 1 0 0 1 1 1 1 HMG-box domain TFIIA PF03153.13 CAR25317.1 - 0.0044 17.1 7.1 0.0046 17.0 7.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3987 PF13148.6 CAR25317.1 - 0.11 11.5 7.8 1.2 8.1 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) YqzL PF14006.6 CAR25317.1 - 2.3 8.6 0.0 2.3 8.6 0.0 2.6 2 1 0 2 2 2 0 YqzL-like protein DRIM PF07539.12 CAR25318.1 - 2.3e-149 498.6 8.8 2.3e-149 498.6 8.8 5.6 7 1 1 8 8 8 2 Down-regulated in metastasis Atx10homo_assoc PF09759.9 CAR25318.1 - 0.0044 17.0 1.6 0.061 13.3 0.1 3.7 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain MMS19_C PF12460.8 CAR25318.1 - 0.023 13.9 0.0 0.023 13.9 0.0 5.4 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal MukF_C PF17193.4 CAR25318.1 - 0.094 12.9 1.2 0.31 11.2 0.1 2.3 2 0 0 2 2 2 0 MukF C-terminal domain V-ATPase_H_N PF03224.14 CAR25318.1 - 0.55 9.5 11.2 6.4 6.0 0.1 5.0 4 0 0 4 4 4 0 V-ATPase subunit H DUF3361 PF11841.8 CAR25318.1 - 0.83 9.6 8.6 4.6 7.2 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3361) DUF4042 PF13251.6 CAR25318.1 - 4.2 7.0 8.2 6.8 6.4 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) Rad21_Rec8_N PF04825.13 CAR25319.1 - 1.4e-22 79.9 0.1 2.5e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CAR25319.1 - 2.3e-10 39.6 0.0 4.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Myb_DNA-bind_5 PF13873.6 CAR25319.1 - 0.012 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ATP-synt_DE_N PF02823.16 CAR25320.1 - 3.7e-16 58.8 0.0 6.8e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Med2 PF11214.8 CAR25321.1 - 6.4e-34 116.1 4.9 1.1e-33 115.3 4.9 1.3 1 0 0 1 1 1 1 Mediator complex subunit 2 Med29 PF11568.8 CAR25321.1 - 7.4e-05 23.0 3.6 0.00013 22.2 3.6 1.4 1 0 0 1 1 1 1 Mediator complex subunit 29 DUF445 PF04286.12 CAR25321.1 - 0.02 14.7 0.8 0.025 14.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) TRADD_N PF09034.10 CAR25321.1 - 2.7 8.1 7.0 1.5 8.9 0.8 2.1 1 1 1 2 2 2 0 TRADD, N-terminal domain PP2C PF00481.21 CAR25322.1 - 1.1e-71 241.6 0.2 1.6e-71 241.0 0.2 1.2 1 1 0 1 1 1 1 Protein phosphatase 2C AAA PF00004.29 CAR25323.1 - 1.1e-40 139.2 0.0 1.8e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR25323.1 - 1.9e-11 43.6 0.4 3.8e-11 42.6 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CAR25323.1 - 2e-09 37.3 0.0 3.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CAR25323.1 - 6.9e-06 26.3 0.0 1.9e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAR25323.1 - 1.5e-05 25.3 0.1 0.017 15.4 0.1 2.6 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 CAR25323.1 - 2.5e-05 23.6 0.0 4.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CAR25323.1 - 7.2e-05 22.8 0.0 0.00032 20.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR25323.1 - 0.00033 21.1 0.1 0.002 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR25323.1 - 0.0014 18.4 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR25323.1 - 0.0036 17.6 0.2 0.0081 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 CAR25323.1 - 0.0089 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CAR25323.1 - 0.015 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CAR25323.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CAR25323.1 - 0.018 14.3 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CAR25323.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CAR25323.1 - 0.021 15.3 0.5 0.068 13.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 CAR25323.1 - 0.028 14.0 0.3 0.37 10.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CAR25323.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CAR25323.1 - 0.055 12.8 0.0 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.21 CAR25323.1 - 0.057 12.8 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CAR25323.1 - 0.1 11.9 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.15 CAR25323.1 - 0.1 12.5 0.4 0.89 9.4 0.0 2.5 3 0 0 3 3 3 0 NTPase AAA_24 PF13479.6 CAR25323.1 - 0.17 11.6 1.2 0.32 10.7 0.3 2.1 2 1 0 2 2 2 0 AAA domain Sulfate_transp PF00916.20 CAR25324.1 - 1.4e-85 287.4 16.7 1.8e-85 287.0 16.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CAR25324.1 - 2.4e-15 56.2 0.0 6.1e-15 54.9 0.0 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CAR25324.1 - 0.00011 22.6 6.3 0.00011 22.6 6.3 2.9 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily CAAD PF14159.6 CAR25324.1 - 0.033 14.0 0.3 0.12 12.2 0.3 2.0 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase STAS_2 PF13466.6 CAR25324.1 - 0.053 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 STAS domain ETF PF01012.21 CAR25325.1 - 5.6e-37 127.4 0.6 8e-37 126.9 0.6 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CAR25325.1 - 5.6e-32 109.6 0.8 1.2e-31 108.6 0.2 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain AAA_33 PF13671.6 CAR25326.1 - 4.7e-05 23.6 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR25326.1 - 8.4e-05 23.1 0.0 0.00025 21.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CAR25326.1 - 0.00015 21.7 0.0 0.00046 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CAR25326.1 - 0.0003 20.1 0.1 0.0019 17.5 0.0 2.1 2 1 1 3 3 3 1 NB-ARC domain Zeta_toxin PF06414.12 CAR25326.1 - 0.00066 19.0 0.0 0.0041 16.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 CAR25326.1 - 0.00087 19.7 0.0 0.0023 18.3 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain RNA_helicase PF00910.22 CAR25326.1 - 0.0015 18.9 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA PF00004.29 CAR25326.1 - 0.0051 17.2 0.0 0.0091 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.18 CAR25326.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_17 PF13207.6 CAR25326.1 - 0.0069 16.8 0.1 0.026 14.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain T2SSE PF00437.20 CAR25326.1 - 0.0074 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CAR25326.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CAR25326.1 - 0.017 14.3 0.0 0.022 14.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CAR25326.1 - 0.02 14.4 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CAR25326.1 - 0.025 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 CAR25326.1 - 0.03 14.9 0.0 0.064 13.8 0.0 1.6 2 0 0 2 2 1 0 ABC transporter MMR_HSR1 PF01926.23 CAR25326.1 - 0.031 14.4 0.0 0.081 13.0 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase MeaB PF03308.16 CAR25326.1 - 0.04 12.9 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SMC_N PF02463.19 CAR25326.1 - 0.042 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 CAR25326.1 - 0.044 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 CAR25326.1 - 0.046 14.0 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR25326.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.21 CAR25326.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase AAA_29 PF13555.6 CAR25326.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.10 CAR25326.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 CAR25326.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CAR25326.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CAR25326.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 1 0 RsgA GTPase RuvB_N PF05496.12 CAR25326.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 CAR25326.1 - 0.2 11.4 0.1 0.43 10.3 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase Rad21_Rec8_N PF04825.13 CAR25328.1 - 1.1e-15 57.7 0.0 2.5e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein NCD1 PF04904.13 CAR25329.1 - 0.0059 16.6 1.0 0.06 13.4 0.1 2.3 2 0 0 2 2 2 1 NAB conserved region 1 (NCD1) GHL13 PF14883.6 CAR25329.1 - 0.014 14.4 0.9 0.017 14.2 0.2 1.4 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 13 ING PF12998.7 CAR25329.1 - 0.029 14.9 1.6 0.029 14.9 1.6 2.4 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding S6OS1 PF15676.5 CAR25329.1 - 0.044 12.3 2.9 0.041 12.4 2.0 1.4 1 1 0 1 1 1 0 Six6 opposite strand transcript 1 family NAGLU_C PF12972.7 CAR25329.1 - 0.45 10.0 4.1 0.32 10.5 1.8 1.7 1 1 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NYD-SP28_assoc PF14775.6 CAR25329.1 - 1.1 9.4 6.7 0.73 10.0 0.8 3.3 3 1 0 3 3 3 0 Sperm tail C-terminal domain FTR1 PF03239.14 CAR25330.1 - 6.9e-101 337.4 8.6 8.6e-101 337.1 8.6 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family PG_binding_3 PF09374.10 CAR25331.1 - 0.16 12.3 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Copper-fist PF00649.18 CAR25332.1 - 1.2e-20 72.7 1.0 1.2e-20 72.7 1.0 2.0 1 1 0 1 1 1 1 Copper fist DNA binding domain DUF3439 PF11921.8 CAR25332.1 - 0.39 10.7 3.5 0.92 9.5 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ran-binding PF05508.11 CAR25333.1 - 9.5e-114 379.6 4.7 1.5e-113 379.0 4.7 1.3 1 0 0 1 1 1 1 RanGTP-binding protein THOC7 PF05615.13 CAR25333.1 - 0.042 14.1 0.6 0.042 14.1 0.6 1.8 2 0 0 2 2 2 0 Tho complex subunit 7 SNF2_N PF00176.23 CAR25334.1 - 1.9e-57 194.6 0.0 2.6e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CAR25334.1 - 1.3e-35 123.2 2.4 1.3e-35 123.2 2.4 1.9 3 0 0 3 3 3 1 Rad54 N terminal Helicase_C PF00271.31 CAR25334.1 - 1.5e-16 60.8 0.0 3.3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CAR25334.1 - 1e-06 28.2 0.1 4.9e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CAR25334.1 - 2.5e-06 27.6 0.0 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zn_clus PF00172.18 CAR25335.1 - 0.00061 19.9 1.8 0.00061 19.9 1.8 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 CAR25337.1 - 1.2e-52 178.8 1.8 1.1e-51 175.7 1.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR25337.1 - 7.1e-50 169.2 1.5 3.1e-49 167.1 1.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR25337.1 - 2.3e-09 37.4 0.3 3.7e-09 36.7 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAR25337.1 - 0.0049 16.4 0.1 0.013 15.0 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Radical_SAM PF04055.21 CAR25337.1 - 0.016 15.6 0.0 0.086 13.2 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily Ldh_1_N PF00056.23 CAR25337.1 - 0.024 14.7 0.1 0.043 13.9 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sua5_yciO_yrdC PF01300.18 CAR25338.1 - 4.6e-46 156.6 0.0 6.6e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CAR25338.1 - 1.2e-29 103.6 0.0 1.8e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF928 PF06051.12 CAR25338.1 - 0.029 14.2 0.4 0.049 13.5 0.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) E1-E2_ATPase PF00122.20 CAR25339.1 - 4.6e-48 163.1 0.1 1.6e-47 161.4 0.1 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CAR25339.1 - 1.3e-46 158.6 0.8 1.3e-46 158.6 0.8 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CAR25339.1 - 7.8e-22 78.6 0.1 2.4e-21 77.0 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR25339.1 - 4e-16 58.9 0.1 8e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CAR25339.1 - 1.5e-13 50.2 0.0 3.5e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR25339.1 - 0.00011 22.0 0.9 0.0013 18.5 1.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNA_pol_Rpb2_6 PF00562.28 CAR25340.1 - 1.5e-112 376.5 0.0 3.6e-112 375.3 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAR25340.1 - 1e-45 155.7 0.1 1.5e-45 155.2 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CAR25340.1 - 1.5e-35 122.5 0.1 3.1e-35 121.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CAR25340.1 - 6.3e-28 96.8 0.0 1.7e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CAR25340.1 - 2.3e-24 85.1 0.0 4.9e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CAR25340.1 - 7.9e-16 58.2 0.0 2.9e-14 53.2 0.0 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Glyco_hydro_17 PF00332.18 CAR25341.1 - 9.6e-10 38.5 2.5 1.4e-07 31.5 0.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 BAP PF06639.11 CAR25341.1 - 0.16 12.3 0.5 0.32 11.4 0.5 1.6 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) Atrophin-1 PF03154.15 CAR25341.1 - 0.56 8.4 1.6 0.84 7.8 1.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family Mid2 PF04478.12 CAR25342.1 - 2.7e-52 176.5 0.8 2.7e-52 176.5 0.8 3.5 1 1 2 4 4 4 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 CAR25342.1 - 0.049 13.1 0.1 0.049 13.1 0.1 3.3 3 0 0 3 3 3 0 Transmembrane alpha-helix domain DUF4366 PF14283.6 CAR25342.1 - 0.32 11.0 1.5 0.84 9.7 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Thg1 PF04446.12 CAR25343.1 - 3.5e-51 172.4 1.2 5e-51 172.0 1.2 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CAR25343.1 - 9.7e-36 122.6 1.1 1.6e-35 121.9 0.1 1.8 2 1 1 3 3 3 1 Thg1 C terminal domain IlvN PF07991.12 CAR25344.1 - 2.6e-45 153.9 0.0 3.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CAR25344.1 - 2.9e-41 141.1 0.0 1.1e-40 139.2 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 CAR25344.1 - 0.034 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TatD_DNase PF01026.21 CAR25344.1 - 0.17 11.2 0.0 0.57 9.5 0.0 1.8 2 0 0 2 2 2 0 TatD related DNase AhpC-TSA PF00578.21 CAR25345.1 - 3.9e-28 97.9 0.0 5.3e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR25345.1 - 2.1e-09 37.2 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CAR25345.1 - 2.6e-08 33.6 0.1 4e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin zf-C2H2 PF00096.26 CAR25346.1 - 6.7e-06 26.3 9.7 0.012 16.1 0.4 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CAR25346.1 - 0.003 17.8 1.9 0.11 12.9 0.7 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CAR25346.1 - 0.028 15.3 12.7 0.61 11.1 0.2 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger DUF629 PF04780.12 CAR25346.1 - 0.058 11.9 1.1 0.82 8.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.6 CAR25346.1 - 0.36 11.4 13.4 1.9 9.1 0.8 4.4 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 CAR25346.1 - 0.37 11.1 0.1 0.37 11.1 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CAR25346.1 - 0.59 9.9 3.6 4.9 7.0 0.1 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type DDE_1 PF03184.19 CAR25347.1 - 5.9e-15 55.4 0.0 2.1e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 CAR25347.1 - 0.016 15.0 0.0 0.052 13.3 0.0 1.9 1 0 0 1 1 1 0 DDE superfamily endonuclease HTH_psq PF05225.16 CAR25347.1 - 0.032 14.0 0.2 13 5.6 0.0 3.0 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Csm1_N PF18504.1 CAR25347.1 - 0.058 13.7 0.6 0.33 11.3 0.6 2.3 1 0 0 1 1 1 0 Csm1 N-terminal domain TAL_FSA PF00923.19 CAR25348.1 - 2.3e-99 332.4 2.1 2.6e-99 332.2 2.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Holin_SPP1 PF04688.13 CAR25348.1 - 0.28 11.4 1.3 2.6 8.3 0.1 2.8 2 1 0 3 3 3 0 SPP1 phage holin DUF2439 PF10382.9 CAR25349.1 - 3.8e-21 75.2 0.8 6.3e-21 74.5 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) zf-CCHC PF00098.23 CAR25350.1 - 2.9e-10 39.8 52.4 0.00055 19.9 5.6 5.8 5 1 0 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.6 CAR25350.1 - 1.3 8.8 33.2 1.9 8.3 1.4 5.1 4 1 1 5 5 5 0 Zinc knuckle Peptidase_M19 PF01244.21 CAR25351.1 - 3.4e-104 348.4 0.0 4e-104 348.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 CAR25351.1 - 0.087 12.6 0.3 0.87 9.3 0.1 2.1 1 1 1 2 2 2 0 Amidohydrolase LRR_6 PF13516.6 CAR25353.1 - 0.0017 18.2 5.2 21 5.5 0.0 5.5 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 CAR25353.1 - 0.02 15.3 0.5 0.02 15.3 0.5 4.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR25353.1 - 0.037 13.8 3.2 0.43 10.4 0.8 3.0 2 0 0 2 2 2 0 Leucine rich repeat Pkinase PF00069.25 CAR25354.1 - 6.7e-70 235.5 0.0 8e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25354.1 - 2.3e-33 115.6 0.0 3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR25354.1 - 0.00011 21.7 0.2 0.00054 19.4 0.2 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR25354.1 - 0.00055 19.3 0.1 0.00089 18.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAR25354.1 - 0.0013 17.7 0.1 0.002 17.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAR25354.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dimerisation PF08100.11 CAR25354.1 - 0.026 14.5 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain FTA2 PF13095.6 CAR25354.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CN_hydrolase PF00795.22 CAR25355.1 - 4.1e-64 216.4 0.0 4.6e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF72 PF01904.18 CAR25355.1 - 0.048 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF72 ORMDL PF04061.14 CAR25356.1 - 4.6e-56 188.4 3.9 5.4e-56 188.2 3.9 1.0 1 0 0 1 1 1 1 ORMDL family ACBP PF00887.19 CAR25357.1 - 2.7e-30 104.4 1.5 2.9e-30 104.3 1.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CAR25357.1 - 0.014 15.8 0.6 0.14 12.5 0.6 2.0 1 1 0 1 1 1 0 FERM central domain CENP-B_N PF04218.13 CAR25357.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HEAT_EZ PF13513.6 CAR25358.1 - 2.4e-13 50.3 20.4 9.2e-08 32.4 0.0 9.2 9 1 1 10 10 9 2 HEAT-like repeat HEAT PF02985.22 CAR25358.1 - 1.8e-11 43.3 25.9 0.00041 20.4 0.0 11.7 12 1 1 13 13 11 1 HEAT repeat IBN_N PF03810.19 CAR25358.1 - 1.2e-09 38.0 3.3 4.2e-09 36.2 0.9 3.3 3 0 0 3 3 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 CAR25358.1 - 1e-06 28.9 9.0 0.00021 21.4 0.0 5.7 2 2 3 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR25358.1 - 1.3e-06 28.7 15.3 0.028 14.8 0.0 7.2 3 3 7 10 10 10 4 HEAT repeats Arm PF00514.23 CAR25358.1 - 3.9e-06 26.7 9.5 0.00067 19.6 0.1 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CAR25358.1 - 4.9e-05 23.0 0.2 0.11 12.0 0.0 4.0 2 1 1 4 4 4 1 CLASP N terminal RIX1 PF08167.12 CAR25358.1 - 0.0024 17.6 0.5 0.12 12.1 0.1 3.8 2 1 1 3 3 3 1 rRNA processing/ribosome biogenesis BP28CT PF08146.12 CAR25358.1 - 0.0034 17.3 1.9 20 5.0 0.0 4.4 4 1 0 4 4 4 0 BP28CT (NUC211) domain Telomere_reg-2 PF10193.9 CAR25358.1 - 0.02 15.3 4.5 0.46 11.0 0.2 3.9 3 1 1 4 4 4 0 Telomere length regulation protein CTD_bind PF04818.13 CAR25358.1 - 0.021 15.7 0.3 7 7.5 0.1 4.2 2 1 1 3 3 2 0 RNA polymerase II-binding domain. TIP120 PF08623.10 CAR25358.1 - 0.039 13.7 2.4 2.1 8.1 0.0 3.8 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) DUF4780 PF16012.5 CAR25358.1 - 0.1 12.1 0.2 0.59 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4780) Vac14_Fab1_bd PF12755.7 CAR25358.1 - 0.18 12.4 1.8 24 5.6 0.0 4.5 4 1 0 4 4 3 0 Vacuolar 14 Fab1-binding region Senescence PF06911.12 CAR25358.1 - 0.19 12.0 0.8 0.86 9.9 0.1 2.4 2 1 0 2 2 2 0 Senescence-associated protein DUF3347 PF11827.8 CAR25358.1 - 0.29 11.3 4.2 0.27 11.4 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3347) RTP1_C1 PF10363.9 CAR25358.1 - 0.35 11.1 9.3 4.2 7.6 1.0 5.5 6 2 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 PAP2 PF01569.21 CAR25359.1 - 6.9e-17 61.5 2.3 1.3e-16 60.6 2.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF5422 PF17459.2 CAR25359.1 - 0.018 15.3 0.2 0.029 14.6 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5422) DUF212 PF02681.14 CAR25359.1 - 0.044 13.9 1.4 1 9.5 0.1 2.2 1 1 1 2 2 2 0 Divergent PAP2 family 6PF2K PF01591.18 CAR25360.1 - 4.6e-63 212.5 1.9 6.2e-63 212.1 1.9 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CAR25360.1 - 7.3e-21 74.7 0.0 1.5e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CAR25360.1 - 0.00042 20.5 0.0 0.00077 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ribosomal_L26 PF16906.5 CAR25361.1 - 4.6e-36 123.2 2.7 5.5e-36 122.9 2.7 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CAR25361.1 - 9.6e-06 25.4 0.6 9.6e-06 25.4 0.6 1.8 2 0 0 2 2 2 1 KOW motif TIM21 PF08294.11 CAR25362.1 - 1.7e-51 173.9 0.0 2e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Glyco_hydro_72 PF03198.14 CAR25363.1 - 4e-133 443.5 1.1 5.5e-133 443.1 1.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CAR25363.1 - 4e-17 62.7 0.9 1e-16 61.4 0.9 1.7 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.15 CAR25364.1 - 0 1349.6 0.0 0 1348.9 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CAR25364.1 - 3.6e-42 143.7 0.1 1.6e-41 141.7 0.1 2.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Abhydrolase_1 PF00561.20 CAR25365.1 - 3.8e-25 89.0 0.0 8.6e-25 87.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR25365.1 - 1.9e-12 47.0 0.0 4e-12 45.9 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR25365.1 - 4.1e-12 47.2 0.0 6.5e-12 46.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CAR25365.1 - 2.8e-05 24.4 0.0 0.00014 22.1 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 CAR25365.1 - 0.0004 20.2 0.0 0.027 14.2 0.0 2.2 1 1 1 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 CAR25365.1 - 0.069 12.7 0.1 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Esterase PF00756.20 CAR25365.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ribosomal_L10 PF00466.20 CAR25367.1 - 6.9e-25 87.1 0.1 1.3e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CAR25367.1 - 1e-20 73.5 0.0 1.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CAR25367.1 - 7.8e-18 64.9 2.0 3.4e-17 62.8 0.8 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein Alba PF01918.21 CAR25368.1 - 6.9e-07 29.0 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Alba DUF3445 PF11927.8 CAR25369.1 - 3.3e-66 223.1 0.0 6.6e-66 222.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) WH2 PF02205.20 CAR25370.1 - 3.1e-14 52.3 1.7 2.1e-10 40.1 0.3 2.7 2 0 0 2 2 2 2 WH2 motif Evr1_Alr PF04777.13 CAR25371.1 - 2.7e-30 104.8 4.3 4.9e-30 104.0 4.3 1.4 1 0 0 1 1 1 1 Erv1 / Alr family SNAD4 PF18750.1 CAR25371.1 - 0.031 14.4 0.3 0.071 13.2 0.1 1.7 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 AAA PF00004.29 CAR25372.1 - 1.7e-37 128.8 0.0 2.9e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR25372.1 - 3.7e-10 39.5 1.9 4.4e-10 39.2 0.3 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_14 PF13173.6 CAR25372.1 - 1.6e-06 28.2 0.0 5e-06 26.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CAR25372.1 - 3.1e-06 27.7 0.7 0.0002 21.8 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CAR25372.1 - 1.2e-05 25.1 0.0 6e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CAR25372.1 - 1.4e-05 25.3 0.0 2.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CAR25372.1 - 6.3e-05 23.2 0.0 0.00021 21.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CAR25372.1 - 6.7e-05 22.9 0.1 0.00052 20.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 CAR25372.1 - 7.8e-05 22.2 0.0 0.32 10.4 0.0 2.4 1 1 0 2 2 2 2 Bacterial TniB protein AAA_22 PF13401.6 CAR25372.1 - 8.3e-05 22.9 0.8 0.0054 17.0 0.0 3.1 1 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CAR25372.1 - 0.00037 20.3 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad17 PF03215.15 CAR25372.1 - 0.00038 20.4 0.0 0.00084 19.3 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 CAR25372.1 - 0.00043 20.8 0.0 0.00086 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 CAR25372.1 - 0.00066 20.0 3.4 0.02 15.2 0.0 3.1 3 1 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_7 PF12775.7 CAR25372.1 - 0.0009 18.8 0.1 0.0032 17.0 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CAR25372.1 - 0.0012 18.9 0.0 0.0028 17.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.13 CAR25372.1 - 0.0013 18.0 0.2 0.003 16.8 0.1 1.5 1 1 1 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR25372.1 - 0.0013 18.1 0.3 0.003 17.0 0.2 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CAR25372.1 - 0.0019 18.6 0.0 0.0066 16.8 0.0 2.0 2 1 0 2 2 2 1 RNA helicase Viral_helicase1 PF01443.18 CAR25372.1 - 0.0024 17.6 0.0 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CAR25372.1 - 0.0039 16.4 0.0 0.0064 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 CAR25372.1 - 0.012 15.5 0.1 0.038 13.9 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 CAR25372.1 - 0.015 15.7 0.8 0.036 14.5 0.0 2.2 3 0 0 3 3 1 0 AAA domain Sigma54_activat PF00158.26 CAR25372.1 - 0.016 14.9 0.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 CAR25372.1 - 0.017 14.7 0.4 0.55 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 CAR25372.1 - 0.017 14.1 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region CPT PF07931.12 CAR25372.1 - 0.018 14.9 0.2 0.038 13.8 0.0 1.7 2 0 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 CAR25372.1 - 0.021 15.3 0.0 0.067 13.7 0.0 2.0 2 1 0 2 2 1 0 ABC transporter AAA_28 PF13521.6 CAR25372.1 - 0.024 14.9 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CAR25372.1 - 0.025 14.5 0.0 0.056 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CAR25372.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 CAR25372.1 - 0.044 13.5 0.0 0.075 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CAR25372.1 - 0.044 13.8 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 CAR25372.1 - 0.052 13.0 0.0 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_11 PF13086.6 CAR25372.1 - 0.059 13.2 0.0 0.16 11.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 CAR25372.1 - 0.073 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 tRNA_lig_kinase PF08303.11 CAR25372.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain SKI PF01202.22 CAR25372.1 - 0.083 13.0 0.2 0.28 11.3 0.1 2.0 2 0 0 2 2 1 0 Shikimate kinase FCH PF00611.23 CAR25372.1 - 0.1 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain NB-ARC PF00931.22 CAR25372.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Guanylate_kin PF00625.21 CAR25372.1 - 0.15 11.8 0.0 1 9.0 0.0 2.3 2 1 1 3 3 3 0 Guanylate kinase MA3 PF02847.17 CAR25373.1 - 1.4e-25 89.4 0.3 4.3e-25 87.9 0.3 1.9 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CAR25373.1 - 1.3e-22 80.6 3.6 1.9e-22 79.9 1.1 2.4 2 0 0 2 2 2 1 MIF4G domain Ran_BP1 PF00638.18 CAR25374.1 - 2.8e-32 111.5 1.0 4.1e-32 111.0 0.2 1.7 2 0 0 2 2 2 1 RanBP1 domain NUP50 PF08911.11 CAR25374.1 - 3.7e-14 53.1 2.6 3.7e-14 53.1 2.6 4.3 4 2 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) Ribosomal_S25 PF03297.15 CAR25375.1 - 5.2e-38 129.3 6.2 5.8e-38 129.2 6.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 CAR25375.1 - 0.00025 20.8 0.1 0.00037 20.2 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain DUF365 PF04033.12 CAR25375.1 - 0.034 14.4 0.3 0.051 13.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) EAP30 PF04157.16 CAR25375.1 - 0.044 13.1 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family UPF0121 PF03661.13 CAR25376.1 - 2.9e-05 23.6 6.2 0.0022 17.4 6.2 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) TctB PF07331.11 CAR25376.1 - 0.002 18.4 4.1 0.018 15.3 0.7 2.2 2 0 0 2 2 2 2 Tripartite tricarboxylate transporter TctB family SNF2_N PF00176.23 CAR25377.1 - 2.5e-40 138.3 0.0 4.5e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 CAR25377.1 - 2.6e-11 43.2 8.3 5.7e-11 42.1 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR25377.1 - 2.3e-09 37.4 9.2 7.1e-09 35.9 9.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAR25377.1 - 4.2e-08 32.9 8.7 1.2e-07 31.5 8.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR25377.1 - 1.4e-07 31.2 6.2 3e-07 30.2 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 CAR25377.1 - 2.5e-07 31.0 0.1 1.6e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CAR25377.1 - 1.3e-05 25.1 6.9 3.1e-05 23.9 6.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CAR25377.1 - 2e-05 24.8 6.0 5.6e-05 23.4 6.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CAR25377.1 - 2.9e-05 23.8 6.6 6e-05 22.8 6.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CAR25377.1 - 0.00082 19.5 10.1 0.0021 18.2 10.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CAR25377.1 - 0.00086 19.2 8.7 0.0024 17.8 8.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CAR25377.1 - 0.055 13.5 3.1 0.15 12.1 3.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CAR25377.1 - 0.06 13.5 3.4 0.17 12.0 3.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 CAR25377.1 - 0.29 10.9 6.5 1.1 8.9 6.5 2.0 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 CAR25377.1 - 0.49 10.2 6.7 1.4 8.7 6.7 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 CAR25377.1 - 0.89 9.4 3.0 2.5 8.0 3.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4407 PF14362.6 CAR25377.1 - 2.6 7.3 8.2 10 5.4 3.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 CAR25379.1 - 8.5e-47 159.7 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25379.1 - 1.2e-27 96.8 0.0 1.7e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR25379.1 - 1.3e-06 28.0 0.0 7.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAR25379.1 - 0.00063 19.7 0.2 0.091 12.7 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CAR25379.1 - 0.0087 15.0 0.0 0.048 12.6 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR25379.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CAR25379.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 MMU163 PF17119.5 CAR25380.1 - 2.4e-15 56.4 0.0 4.4e-15 55.5 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis eIF2A PF08662.11 CAR25381.1 - 4.5e-77 258.3 0.0 1.1e-76 257.1 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CAR25381.1 - 5.2e-05 23.9 1.0 3.4 8.7 0.0 4.3 4 1 1 5 5 5 2 WD domain, G-beta repeat EBV-NA1 PF02905.14 CAR25381.1 - 0.29 10.9 1.0 0.53 10.1 1.0 1.3 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Pkinase PF00069.25 CAR25383.1 - 2.6e-28 99.1 0.0 5.3e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25383.1 - 6.2e-16 58.5 0.0 9.7e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR25383.1 - 5e-05 23.4 0.0 0.00019 21.5 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR25383.1 - 6e-05 22.0 0.0 7.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR25383.1 - 0.00012 21.5 0.1 0.00019 20.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CAR25383.1 - 0.0043 16.6 0.1 0.0081 15.7 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 CAR25383.1 - 0.042 12.8 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF3410 PF11890.8 CAR25383.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) FA_hydroxylase PF04116.13 CAR25384.1 - 6.4e-22 78.3 15.8 6.4e-22 78.3 15.8 2.5 2 1 1 3 3 3 2 Fatty acid hydroxylase superfamily ABC_tran PF00005.27 CAR25385.1 - 8.8e-17 61.9 0.3 7.3e-16 58.9 0.2 2.3 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CAR25385.1 - 1.6e-10 41.3 4.7 3.7e-05 23.7 0.4 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR25385.1 - 9.7e-07 28.4 0.0 1.2e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR25385.1 - 0.00019 22.0 0.0 0.00023 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CAR25385.1 - 0.00025 20.7 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CAR25385.1 - 0.0018 18.1 0.0 0.0024 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR25385.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CAR25385.1 - 0.033 14.3 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF3584 PF12128.8 CAR25385.1 - 0.065 10.8 0.0 0.087 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_10 PF12846.7 CAR25385.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.6 CAR25385.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CAR25385.1 - 0.14 12.2 0.3 0.25 11.4 0.3 1.3 1 0 0 1 1 1 0 Dynamin family Sigma54_activat PF00158.26 CAR25385.1 - 0.15 11.8 0.1 12 5.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain WD40 PF00400.32 CAR25386.1 - 9.7e-12 45.2 2.8 0.41 11.6 0.1 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat SDA1 PF05285.12 CAR25386.1 - 4.9 6.5 50.6 5.8 6.2 1.1 2.1 2 0 0 2 2 2 0 SDA1 RabGAP-TBC PF00566.18 CAR25387.1 - 3.9e-14 52.8 0.0 9.9e-14 51.5 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Myb_DNA-bind_4 PF13837.6 CAR25388.1 - 7.4e-06 26.3 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR25388.1 - 0.013 15.8 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 Myb-like DNA-binding domain FlxA PF14282.6 CAR25388.1 - 0.022 14.8 0.4 0.039 13.9 0.4 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF4349 PF14257.6 CAR25388.1 - 0.079 12.4 0.2 0.15 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LPP PF04728.13 CAR25388.1 - 0.26 11.7 1.2 0.6 10.5 1.2 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Myb_DNA-bind_4 PF13837.6 CAR25389.1 - 0.0033 17.8 0.1 0.0058 17.0 0.1 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Glyco_hydro_47 PF01532.20 CAR25392.1 - 4e-87 293.0 0.0 4.9e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Wzy_C PF04932.15 CAR25392.1 - 0.21 11.2 0.0 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 O-Antigen ligase SHMT PF00464.19 CAR25393.1 - 1.5e-209 695.6 0.0 1.7e-209 695.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 CAR25393.1 - 1.3e-06 27.8 0.0 2.7e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CAR25393.1 - 0.00017 20.7 0.0 0.00025 20.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAR25393.1 - 0.00061 19.2 0.0 0.00098 18.5 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase FR47 PF08445.10 CAR25393.1 - 0.086 12.8 0.0 0.87 9.6 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein DegT_DnrJ_EryC1 PF01041.17 CAR25393.1 - 0.097 12.0 0.1 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CAR25393.1 - 0.16 10.5 0.0 0.27 9.7 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAR25394.1 - 4.7e-24 85.0 0.0 6.1e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CAR25394.1 - 0.0076 15.5 0.1 0.015 14.5 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.19 CAR25394.1 - 0.043 13.9 0.7 0.24 11.4 0.1 2.2 2 0 0 2 2 2 0 B12 binding domain Peroxin-22 PF12827.7 CAR25394.1 - 0.13 12.2 0.3 0.33 10.9 0.3 1.7 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family DnaJ PF00226.31 CAR25395.1 - 3.7e-18 65.4 0.3 3.7e-18 65.4 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain Cloacin_immun PF03513.14 CAR25395.1 - 0.061 13.7 1.3 0.16 12.3 0.7 2.1 1 1 1 2 2 2 0 Cloacin immunity protein DUF3878 PF12994.7 CAR25395.1 - 0.22 11.0 5.7 0.45 9.9 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) DUF1788 PF08747.11 CAR25395.1 - 2.1 8.4 7.5 0.34 10.9 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1788) LMBR1 PF04791.16 CAR25395.1 - 2.7 6.8 5.4 2.8 6.7 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein bZIP_2 PF07716.15 CAR25396.1 - 0.00029 20.9 9.5 0.00029 20.9 9.5 1.8 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 CAR25396.1 - 0.0036 17.4 12.3 0.016 15.3 12.3 2.0 1 1 0 1 1 1 1 bZIP transcription factor RNase_T PF00929.24 CAR25397.1 - 5.7e-35 121.3 0.2 1.2e-34 120.3 0.2 1.5 1 0 0 1 1 1 1 Exonuclease RE_EcoO109I PF14511.6 CAR25397.1 - 0.12 12.0 0.3 0.19 11.3 0.3 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease EcoO109I Pkinase PF00069.25 CAR25398.1 - 1.3e-57 195.1 0.0 8.6e-35 120.4 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25398.1 - 7.8e-26 90.9 0.1 4.8e-19 68.7 0.1 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR25398.1 - 4.1e-07 29.6 0.0 0.00024 20.5 0.0 2.5 1 1 0 2 2 2 2 Kinase-like Response_reg PF00072.24 CAR25398.1 - 9e-07 29.0 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 CAR25398.1 - 0.0012 19.0 0.0 0.0039 17.4 0.0 1.9 1 0 0 1 1 1 1 PAS domain Kdo PF06293.14 CAR25398.1 - 0.002 17.6 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR25398.1 - 0.0021 18.1 0.1 0.067 13.1 0.3 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 CAR25398.1 - 0.016 14.8 0.1 7.4 6.1 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CAR25398.1 - 0.053 13.1 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 RIO1 family PAS_4 PF08448.10 CAR25398.1 - 0.096 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.11 CAR25398.1 - 0.1 11.6 1.0 0.13 11.3 0.1 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 tRNA_synthFbeta PF17759.1 CAR25399.1 - 1e-43 149.3 0.0 2.2e-43 148.2 0.0 1.5 2 0 0 2 2 2 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CAR25399.1 - 9.2e-32 109.1 0.9 1.9e-29 101.7 0.2 2.7 2 1 0 2 2 2 2 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CAR25399.1 - 2.1e-29 102.4 0.0 3.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CAR25399.1 - 6.8e-19 67.9 0.0 1.7e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF3533 PF12051.8 CAR25399.1 - 0.048 12.6 0.4 0.48 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) DUF726 PF05277.12 CAR25400.1 - 2.8e-134 447.4 1.9 1.3e-133 445.2 1.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF726) Ribosomal_L22e PF01776.17 CAR25401.1 - 2.8e-40 137.1 1.1 3.6e-40 136.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family RIB43A PF05914.12 CAR25401.1 - 0.031 13.1 0.0 0.036 12.8 0.0 1.1 1 0 0 1 1 1 0 RIB43A Methyltransf_34 PF11312.8 CAR25402.1 - 8.7e-88 294.5 0.0 1.2e-87 294.1 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Mob1_phocein PF03637.17 CAR25403.1 - 1.4e-64 217.2 1.8 2.1e-64 216.6 1.8 1.3 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol PF00940.19 CAR25404.1 - 8.1e-184 611.2 0.0 1.2e-183 610.7 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CAR25404.1 - 3e-104 349.1 2.0 6.5e-104 347.9 2.0 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Tubulin PF00091.25 CAR25405.1 - 4.7e-68 229.3 0.0 8e-68 228.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAR25405.1 - 3e-42 143.7 0.1 5.8e-42 142.8 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CAR25405.1 - 0.0017 18.1 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CAR25405.1 - 0.0062 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.9 CAR25405.1 - 0.014 15.7 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain PI_PP_I PF18363.1 CAR25405.1 - 0.067 13.4 0.1 8.1 6.7 0.1 2.7 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain Ras PF00071.22 CAR25406.1 - 3e-64 215.5 0.4 3.6e-64 215.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR25406.1 - 2e-35 121.6 0.2 3.5e-35 120.8 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR25406.1 - 1.6e-17 63.5 0.2 2e-17 63.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR25406.1 - 1.1e-05 24.9 0.3 1.7e-05 24.3 0.3 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR25406.1 - 0.00015 21.4 0.4 0.00049 19.7 0.2 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAR25406.1 - 0.00016 21.7 0.1 0.00022 21.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CAR25406.1 - 0.00096 18.6 0.5 0.0012 18.3 0.1 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CAR25406.1 - 0.0011 18.9 0.4 0.15 12.0 0.0 2.4 1 1 1 2 2 2 1 RsgA GTPase Septin PF00735.18 CAR25406.1 - 0.029 13.7 0.1 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Septin AAA PF00004.29 CAR25406.1 - 0.041 14.3 0.1 1.5 9.3 0.0 2.4 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CAR25406.1 - 0.043 14.3 0.6 0.18 12.3 0.6 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CAR25406.1 - 0.043 14.2 0.0 0.069 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CAR25406.1 - 0.065 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CAR25406.1 - 0.096 12.1 0.0 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 CAR25406.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TMEM208_SND2 PF05620.11 CAR25407.1 - 1.8e-48 164.5 0.0 2e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 CCB1 PF12046.8 CAR25407.1 - 0.17 11.2 0.2 0.31 10.4 0.2 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF4231 PF14015.6 CAR25407.1 - 0.19 12.2 0.6 0.32 11.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Actin PF00022.19 CAR25408.1 - 2.9e-150 500.4 0.0 8.3e-150 498.9 0.0 1.6 1 1 0 1 1 1 1 Actin Sugar_tr PF00083.24 CAR25409.1 - 3.6e-77 260.2 27.8 4.5e-77 259.8 27.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR25409.1 - 4.5e-23 81.8 38.1 1.8e-20 73.2 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR25409.1 - 0.00061 18.3 2.6 0.00061 18.3 2.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Arteri_Gl PF00951.18 CAR25409.1 - 0.0059 16.4 1.1 0.0059 16.4 1.1 3.1 3 1 0 3 3 3 1 Arterivirus GL envelope glycoprotein Peptidase_M56 PF05569.11 CAR25409.1 - 0.57 9.3 3.0 9.3 5.3 0.1 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 SPC22 PF04573.12 CAR25410.1 - 1.6e-56 190.4 0.2 1.9e-56 190.2 0.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR_2 PF13041.6 CAR25411.1 - 2.8e-16 59.5 8.8 9.1e-05 22.6 0.1 7.7 5 1 3 8 8 8 5 PPR repeat family PPR PF01535.20 CAR25411.1 - 6.6e-11 41.7 11.8 0.24 11.7 0.0 8.1 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 CAR25411.1 - 1e-10 41.4 0.0 3.7e-05 23.2 0.0 3.6 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CAR25411.1 - 4e-09 36.4 1.6 0.0049 16.9 0.0 4.4 3 1 1 4 4 4 2 Pentatricopeptide repeat domain TPR_14 PF13428.6 CAR25411.1 - 0.0012 19.5 0.0 4.3 8.4 0.0 5.1 4 1 2 6 6 6 1 Tetratricopeptide repeat COX5A PF02284.16 CAR25411.1 - 0.0049 16.9 0.0 22 5.1 0.0 4.1 2 1 1 3 3 3 1 Cytochrome c oxidase subunit Va TPR_8 PF13181.6 CAR25411.1 - 0.058 13.6 1.0 2.1 8.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat 7TMR-HDED PF07697.11 CAR25411.1 - 0.83 9.7 6.9 11 6.1 0.1 3.9 3 1 0 3 3 3 0 7TM-HD extracellular rRNA_processing PF08524.11 CAR25412.1 - 2.6e-32 111.9 32.7 3e-32 111.7 32.7 1.0 1 0 0 1 1 1 1 rRNA processing Band_3_cyto PF07565.13 CAR25412.1 - 7.3 6.3 11.3 8.8 6.0 11.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GTP_EFTU PF00009.27 CAR25413.1 - 7.4e-63 211.6 0.2 1.9e-62 210.3 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CAR25413.1 - 2e-37 127.7 0.1 6.3e-37 126.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 CAR25413.1 - 5.2e-30 103.3 0.0 1.7e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 CAR25413.1 - 1.5e-24 85.8 0.0 3.4e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR25413.1 - 9.4e-13 48.4 0.4 2.7e-12 46.9 0.4 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CAR25413.1 - 3.7e-06 26.8 0.0 8.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CAR25413.1 - 0.0055 16.8 0.0 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 CAR25413.1 - 0.024 15.1 0.0 0.62 10.6 0.0 2.6 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain DUF442 PF04273.13 CAR25413.1 - 0.058 13.5 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Cu-oxidase_2 PF07731.14 CAR25414.1 - 1.4e-45 154.4 7.6 2.5e-40 137.4 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAR25414.1 - 1.1e-36 125.5 3.7 8.4e-36 122.6 0.5 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 CAR25414.1 - 1.1e-33 116.6 5.1 2e-29 102.7 0.7 3.2 3 0 0 3 3 3 2 Multicopper oxidase ADH_N PF08240.12 CAR25415.1 - 2.5e-27 94.9 0.1 6e-27 93.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR25415.1 - 3.2e-27 95.1 0.2 4.6e-27 94.6 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CAR25415.1 - 2.7e-11 43.4 0.1 4.2e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CAR25415.1 - 9.1e-08 33.2 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 CAR25415.1 - 0.0064 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 CAR25415.1 - 0.031 13.6 0.1 0.09 12.1 0.1 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 CAR25415.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CAR25415.1 - 0.038 13.3 0.3 0.061 12.6 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Med14 PF08638.11 CAR25416.1 - 1.4e-57 194.2 1.0 2.9e-57 193.2 1.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 Peptidase_C53 PF05550.11 CAR25416.1 - 0.1 12.3 0.1 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Pestivirus Npro endopeptidase C53 VASt PF16016.5 CAR25417.1 - 3.8e-39 134.6 0.0 8.4e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CAR25417.1 - 3.2e-25 88.2 0.1 7.7e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 GRAM domain CENP-B_dimeris PF09026.10 CAR25417.1 - 0.54 10.7 9.6 0.22 11.9 6.9 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain USP8_dimer PF08969.11 CAR25418.1 - 8.9e-07 29.1 0.0 1.9e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 USP8 dimerisation domain OTU PF02338.19 CAR25419.1 - 1.4e-06 28.8 0.0 2.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_jaz PF12171.8 CAR25420.1 - 4e-10 39.7 6.3 1.7e-09 37.7 3.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CAR25420.1 - 0.00047 20.4 0.3 0.00098 19.4 0.1 1.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CAR25420.1 - 0.0088 16.5 3.2 0.85 10.1 1.3 3.0 2 1 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 CAR25420.1 - 0.031 14.6 5.4 0.18 12.2 2.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CAR25420.1 - 0.053 14.4 1.2 0.14 13.0 0.6 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 CAR25420.1 - 0.073 12.8 1.5 0.13 12.0 1.5 1.4 1 0 0 1 1 1 0 U1 zinc finger Ribosomal_L16 PF00252.18 CAR25421.1 - 3.7e-42 143.5 0.1 4.6e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PMM PF03332.13 CAR25422.1 - 2.3e-113 377.4 0.4 2.7e-113 377.2 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CAR25422.1 - 2.7e-05 24.0 0.0 0.00043 20.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR25422.1 - 0.11 12.7 0.1 0.18 12.1 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1640 PF07798.11 CAR25423.1 - 8.8e-54 182.2 5.8 1e-53 182.0 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Spc7 PF08317.11 CAR25423.1 - 0.0098 14.8 2.4 0.013 14.4 2.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein GCN5L1 PF06320.13 CAR25423.1 - 0.016 15.4 2.2 2.9 8.1 0.0 2.6 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) FlaC_arch PF05377.11 CAR25423.1 - 0.038 14.4 2.1 7.8 7.0 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3410 PF11890.8 CAR25423.1 - 0.062 13.1 1.1 0.11 12.3 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) Uso1_p115_C PF04871.13 CAR25423.1 - 0.085 13.2 4.2 0.084 13.2 1.5 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Apolipoprotein PF01442.18 CAR25423.1 - 0.12 12.2 4.9 0.26 11.2 4.9 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain XhlA PF10779.9 CAR25423.1 - 0.15 12.3 3.0 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF4439 PF14530.6 CAR25423.1 - 0.17 12.6 0.1 0.34 11.6 0.0 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4439) Sulfatase_C PF14707.6 CAR25423.1 - 0.21 12.3 0.4 10 6.9 0.0 2.3 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase COG2 PF06148.11 CAR25423.1 - 0.23 11.5 7.0 0.091 12.9 1.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Phage_GPO PF05929.11 CAR25423.1 - 0.79 9.3 4.2 0.16 11.6 0.9 1.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Baculo_PEP_C PF04513.12 CAR25423.1 - 0.9 9.6 3.3 12 6.0 3.3 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATPase PF06745.13 CAR25423.1 - 1 8.7 5.9 1 8.7 0.5 2.7 1 1 2 3 3 3 0 KaiC Phage_lysis PF03245.13 CAR25423.1 - 1.2 9.3 8.1 0.51 10.5 1.5 2.1 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein FliT PF05400.13 CAR25423.1 - 3 8.7 6.4 0.83 10.5 2.7 2.0 2 1 0 2 2 2 0 Flagellar protein FliT Csm1_N PF18504.1 CAR25423.1 - 3.1 8.2 6.1 4.8 7.6 0.2 2.8 2 1 1 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 CAR25423.1 - 4.1 7.6 9.0 2.9 8.1 5.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RCC1 PF00415.18 CAR25424.1 - 9.9e-32 109.3 2.4 4.7e-10 39.9 0.1 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAR25424.1 - 7.1e-18 63.9 10.6 3.6e-10 39.4 0.5 4.8 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat DUF4574 PF15141.6 CAR25424.1 - 0.01 15.7 0.5 0.033 14.1 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 V-SNARE_C PF12352.8 CAR25425.1 - 2.1e-05 24.7 2.2 2.1e-05 24.7 2.2 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CAR25425.1 - 0.0006 19.7 0.3 0.0006 19.7 0.3 2.1 2 0 0 2 2 2 1 Sec20 Bap31_Bap29_C PF18035.1 CAR25425.1 - 0.0056 16.7 0.7 0.018 15.1 0.7 1.9 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF3573 PF12097.8 CAR25425.1 - 0.21 10.4 2.7 0.33 9.7 2.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) EMP24_GP25L PF01105.24 CAR25425.1 - 0.23 11.4 4.6 1.3 8.9 0.6 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DASH_Duo1 PF08651.10 CAR25425.1 - 0.42 10.4 4.7 0.57 10.0 0.2 2.7 3 0 0 3 3 3 0 DASH complex subunit Duo1 V_ATPase_I PF01496.19 CAR25425.1 - 0.73 7.7 8.7 0.22 9.4 4.1 1.8 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family CLZ PF16526.5 CAR25425.1 - 0.97 9.8 8.7 0.18 12.2 2.5 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HIP1_clath_bdg PF16515.5 CAR25425.1 - 1.2 9.8 17.4 0.45 11.2 7.8 3.0 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4407 PF14362.6 CAR25425.1 - 1.5 8.1 6.5 1.7 7.9 6.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CAR25425.1 - 2.1 7.1 13.0 0.81 8.5 8.5 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 CAR25425.1 - 2.5 8.3 10.4 0.8 10.0 4.5 2.7 2 1 1 3 3 3 0 Cortexillin I, coiled coil DEP PF00610.21 CAR25427.1 - 9.7e-12 44.8 0.4 2.9e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.27 CAR25427.1 - 6.1e-11 42.4 0.2 6.1e-11 42.4 0.2 2.8 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 CAR25427.1 - 4.8e-06 26.8 0.0 2.9e-05 24.3 0.0 2.4 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Cas_GSU0053 PF09617.10 CAR25427.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) DUF632 PF04782.12 CAR25427.1 - 0.033 13.5 2.0 0.05 12.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF632) MCU PF04678.13 CAR25427.1 - 0.51 10.4 5.3 0.29 11.2 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Rdx PF10262.9 CAR25428.1 - 8.9e-27 93.1 0.1 1.1e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Rdx family Lectin_leg-like PF03388.13 CAR25429.1 - 8.5e-43 146.3 0.1 1.1e-42 145.9 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CAR25429.1 - 0.0098 15.9 0.2 0.21 11.6 0.2 2.2 1 1 0 1 1 1 1 Bacterial lectin CRC_subunit PF08624.10 CAR25430.1 - 1.4e-41 142.0 0.0 2.8e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lyase_1 PF00206.20 CAR25431.1 - 2.4e-98 329.4 0.0 3.5e-98 328.8 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CAR25431.1 - 8.8e-22 77.7 0.0 2.5e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal adh_short PF00106.25 CAR25432.1 - 1.7e-09 37.5 0.0 1.8e-08 34.1 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 CAR25432.1 - 6.7e-06 25.7 0.1 1.1e-05 25.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 CAR25432.1 - 0.00037 19.9 0.1 0.00057 19.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 CAR25432.1 - 0.00096 18.8 0.0 0.0036 16.9 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CAR25432.1 - 0.0041 17.0 0.1 0.0057 16.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CAR25432.1 - 0.0048 16.8 0.2 0.0073 16.2 0.2 1.3 1 0 0 1 1 1 1 KR domain ApbA PF02558.16 CAR25432.1 - 0.01 15.5 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CAR25432.1 - 0.028 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CAR25432.1 - 0.045 14.0 0.1 0.072 13.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CAR25432.1 - 0.098 13.1 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 CAR25432.1 - 0.14 12.7 0.1 0.3 11.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.23 CAR25432.1 - 0.2 11.7 0.2 0.35 11.0 0.2 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Flocculin_t3 PF13928.6 CAR25433.1 - 6.3e-06 26.6 29.9 0.00011 22.7 14.2 7.6 4 3 2 6 6 6 2 Flocculin type 3 repeat Sugar_tr PF00083.24 CAR25434.1 - 2.3e-132 442.1 22.1 2.6e-132 441.9 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR25434.1 - 2.6e-20 72.7 33.8 5.3e-17 61.8 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 CAR25434.1 - 4.8 7.5 13.4 0.12 12.6 5.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) zf-BED PF02892.15 CAR25435.1 - 6.3e-08 32.5 1.6 1.8e-07 31.1 1.6 1.8 1 0 0 1 1 1 1 BED zinc finger Dimer_Tnp_hAT PF05699.14 CAR25435.1 - 3.1e-06 26.9 0.0 7.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_12 PF18658.1 CAR25435.1 - 0.013 15.0 0.1 0.035 13.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger C2H2-type ABC2_membrane PF01061.24 CAR25436.1 - 2.7e-81 272.0 49.9 2.8e-42 144.5 17.8 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR25436.1 - 1.1e-40 139.3 0.1 3.9e-19 69.5 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CAR25436.1 - 2.7e-32 110.5 15.7 1.1e-30 105.4 0.4 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CAR25436.1 - 1.9e-18 66.8 0.1 7.4e-18 64.9 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CAR25436.1 - 1.1e-07 31.6 0.5 2.8e-06 27.1 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CAR25436.1 - 2.9e-07 31.0 0.0 7.7e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR25436.1 - 3.4e-06 27.0 0.0 0.00041 20.3 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CAR25436.1 - 1.6e-05 24.5 1.0 0.0062 16.3 0.4 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CAR25436.1 - 2.5e-05 24.8 0.0 0.0079 16.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CAR25436.1 - 4.4e-05 23.4 0.0 0.066 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CAR25436.1 - 0.00046 20.1 0.1 0.26 11.2 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 CAR25436.1 - 0.00053 20.2 0.0 0.39 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 CAR25436.1 - 0.0012 18.3 0.0 0.072 12.5 0.0 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CAR25436.1 - 0.0061 16.8 0.3 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR25436.1 - 0.0065 16.7 2.0 0.57 10.5 0.1 3.4 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 CAR25436.1 - 0.011 16.3 0.0 0.011 16.3 0.0 2.9 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.23 CAR25436.1 - 0.053 13.6 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 CAR25436.1 - 0.082 12.6 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CAR25436.1 - 0.087 12.6 0.3 3 7.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Motilin_ghrelin PF04644.12 CAR25436.1 - 0.17 11.7 0.8 0.45 10.4 0.2 2.0 2 0 0 2 2 2 0 Motilin/ghrelin cobW PF02492.19 CAR25436.1 - 0.31 10.6 2.1 5.9 6.4 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane_3 PF12698.7 CAR25436.1 - 1.5 7.8 44.3 0.59 9.2 14.5 3.0 2 2 0 2 2 2 0 ABC-2 family transporter protein Alpha-amylase PF00128.24 CAR25437.1 - 1.4e-117 393.0 0.0 2.2e-117 392.4 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CAR25437.1 - 0.00021 21.4 0.0 0.00053 20.1 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 CAR25437.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Ldh_1_N PF00056.23 CAR25439.1 - 3.8e-42 143.7 0.5 5.8e-42 143.1 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAR25439.1 - 2.2e-22 79.7 0.0 3.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 CAR25439.1 - 0.0006 19.4 0.5 0.0015 18.1 0.5 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 CAR25439.1 - 0.0015 18.1 0.8 0.015 14.8 0.1 2.4 1 1 0 2 2 2 1 Family 4 glycosyl hydrolase AlaDh_PNT_C PF01262.21 CAR25439.1 - 0.0021 17.4 0.9 0.0062 15.9 0.2 1.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CAR25439.1 - 0.026 14.4 0.1 0.048 13.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CAR25439.1 - 0.042 13.4 0.5 0.06 12.9 0.5 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 CAR25439.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CAR25439.1 - 0.077 13.3 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 CAR25439.1 - 0.14 12.7 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DASH_Ask1 PF08655.10 CAR25439.1 - 0.14 12.1 0.2 3.9 7.4 0.0 2.5 3 0 0 3 3 3 0 DASH complex subunit Ask1 2-Hacid_dh_C PF02826.19 CAR25439.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CAR25440.1 - 1.8e-40 138.3 0.9 3.1e-40 137.5 0.9 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAR25440.1 - 5.5e-29 101.2 0.1 1e-28 100.4 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 CAR25440.1 - 7.5e-05 22.4 1.7 0.0003 20.4 0.2 2.5 2 1 1 3 3 3 1 Family 4 glycosyl hydrolase ThiF PF00899.21 CAR25440.1 - 0.00017 21.0 0.1 0.0003 20.2 0.1 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 CAR25440.1 - 0.00052 20.4 0.4 0.0011 19.4 0.4 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding DAO PF01266.24 CAR25440.1 - 0.0012 18.5 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 CAR25440.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CAR25440.1 - 0.0082 15.7 2.0 0.074 12.6 0.7 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 CAR25440.1 - 0.019 14.9 0.1 0.045 13.6 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CAR25440.1 - 0.03 14.6 2.1 0.039 14.2 0.6 2.1 2 1 0 2 2 2 0 TrkA-N domain DUP PF00674.18 CAR25441.1 - 5.5e-23 81.1 2.4 1.6e-13 50.7 0.0 2.5 2 1 0 2 2 2 2 DUP family DUF3916 PF13079.6 CAR25441.1 - 0.023 14.6 0.3 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3916) DUF4085 PF13315.6 CAR25441.1 - 0.15 11.7 0.2 0.15 11.7 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Pyr_redox_2 PF07992.14 CAR25442.1 - 1.2e-36 126.4 0.3 1.4e-36 126.2 0.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR25442.1 - 2.2e-13 50.1 0.4 1.8e-09 37.3 0.3 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR25442.1 - 1e-10 42.0 2.9 9.4e-06 26.1 0.1 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CAR25442.1 - 2.1e-07 30.4 0.8 5e-06 25.9 0.1 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CAR25442.1 - 0.00045 19.6 0.4 0.012 14.9 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CAR25442.1 - 0.5 9.4 1.2 1.2 8.1 0.2 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein Aminotran_1_2 PF00155.21 CAR25443.1 - 2.4e-16 59.9 0.0 3.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CAR25443.1 - 2.8e-05 23.1 0.0 0.00015 20.7 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 CAR25444.1 - 3.3e-44 151.5 0.0 3.9e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CAR25444.1 - 1.7e-05 23.6 0.0 2.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAR25444.1 - 1.9e-05 23.8 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAR25444.1 - 0.00019 20.8 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 CAR25444.1 - 0.0063 15.4 0.0 0.0092 14.9 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_MocR PF12897.7 CAR25444.1 - 0.052 12.3 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Ribosomal_S14 PF00253.21 CAR25444.1 - 0.053 13.3 0.3 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DegT_DnrJ_EryC1 PF01041.17 CAR25444.1 - 0.2 10.9 0.0 0.3 10.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 CAR25445.1 - 1.6e-40 139.1 27.1 2.4e-40 138.5 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Mannosyl_trans3 PF11051.8 CAR25446.1 - 4.3e-73 246.1 0.1 7.5e-73 245.3 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative TniB PF05621.11 CAR25446.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein adh_short PF00106.25 CAR25448.1 - 5.4e-10 39.1 0.1 8.7e-09 35.1 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR25448.1 - 1.4e-05 24.8 0.0 4.4e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CAR25448.1 - 0.0005 19.6 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 CAR25448.1 - 0.0018 17.6 0.1 0.0037 16.6 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 CAR25448.1 - 0.035 13.2 0.1 0.048 12.8 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain KR PF08659.10 CAR25448.1 - 0.04 13.8 0.3 0.082 12.8 0.3 1.5 1 1 0 1 1 1 0 KR domain Oxidored_nitro PF00148.19 CAR25448.1 - 0.061 12.0 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase THF_DHG_CYH_C PF02882.19 CAR25448.1 - 0.064 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 CAR25448.1 - 0.17 12.3 0.2 0.37 11.2 0.2 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Alkyl_sulf_dimr PF14863.6 CAR25449.1 - 2.1e-55 187.0 0.3 4e-55 186.1 0.3 1.5 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 CAR25449.1 - 6.4e-41 140.5 0.1 9.5e-41 140.0 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 CAR25449.1 - 2.4e-35 121.5 0.4 4.2e-35 120.8 0.4 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 CAR25449.1 - 3.6e-06 26.6 0.0 1.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain SCP2 PF02036.17 CAR25449.1 - 0.00039 20.9 0.0 0.00089 19.7 0.0 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Amidohydro_1 PF01979.20 CAR30025.1 - 1.9e-38 132.7 0.1 2.2e-38 132.4 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR30025.1 - 7.6e-12 45.4 0.0 7.5e-07 29.0 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family IF2_N PF04760.15 CAR30025.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Acetyltransf_1 PF00583.25 CAR30027.1 - 5.5e-07 29.8 0.0 7.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR30027.1 - 5e-05 23.2 0.1 0.00018 21.5 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR30027.1 - 0.0024 18.3 0.0 0.004 17.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CAR30027.1 - 0.014 16.1 0.0 0.025 15.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CAR30027.1 - 0.025 14.0 0.1 0.025 14.0 0.1 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Mito_carr PF00153.27 CAR30028.1 - 6e-56 186.4 2.3 5.7e-19 67.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HIM1 PF08732.10 CAR30029.1 - 6.1e-10 38.9 0.0 3e-09 36.6 0.0 1.8 1 1 1 2 2 2 1 HIM1 NAD_binding_10 PF13460.6 CAR30029.1 - 2.7e-06 27.4 0.0 3.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CAR30029.1 - 3.1e-05 23.5 0.0 5e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CAR30029.1 - 5.7e-05 23.5 0.0 0.00037 20.9 0.0 2.0 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF1471 PF07338.13 CAR30029.1 - 0.045 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) NmrA PF05368.13 CAR30029.1 - 0.072 12.6 0.1 0.57 9.7 0.1 2.2 1 1 0 1 1 1 0 NmrA-like family Globin PF00042.22 CAR30030.1 - 0.00092 19.8 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Globin Sugar_tr PF00083.24 CAR30031.1 - 1.5e-129 432.8 23.1 1.7e-129 432.6 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30031.1 - 2.3e-21 76.1 31.4 9.6e-18 64.2 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 CAR30031.1 - 6.5 7.1 13.7 0.046 13.9 3.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) ATG2_CAD PF13329.6 CAR30032.1 - 2.1e-33 115.3 1.7 7.9e-33 113.4 0.2 2.6 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 CAR30032.1 - 1.2e-28 99.2 0.2 3.3e-28 97.9 0.2 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain SesA PF17107.5 CAR30032.1 - 0.0021 18.2 0.1 0.0069 16.6 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases VPS13_C PF16909.5 CAR30032.1 - 0.0024 17.7 1.5 0.011 15.6 0.1 2.8 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal RhoGAP PF00620.27 CAR30033.1 - 1e-34 119.5 0.4 2.1e-33 115.3 0.0 2.8 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 CAR30033.1 - 2.8e-23 81.9 50.4 6.5e-12 45.5 6.0 4.6 4 0 0 4 4 4 4 LIM domain G6PD_C PF02781.16 CAR30034.1 - 5.7e-110 367.1 0.0 8.1e-110 366.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CAR30034.1 - 4.4e-61 206.6 0.0 2e-60 204.4 0.0 2.1 3 0 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Fe_hyd_lg_C PF02906.14 CAR30035.1 - 3.8e-62 210.1 0.0 5.1e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_S8 PF00082.22 CAR30036.1 - 2.5e-38 132.0 1.3 4.1e-38 131.3 1.3 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CAR30036.1 - 4.1e-25 87.6 0.9 1.1e-24 86.3 0.9 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain Orf78 PF06024.12 CAR30036.1 - 0.19 12.0 0.0 0.51 10.7 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Peptidase_M56 PF05569.11 CAR30036.1 - 0.25 10.5 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ytp1 PF10355.9 CAR30037.1 - 6.8e-60 202.6 15.7 6.9e-58 196.0 15.7 2.3 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) COX14 PF14880.6 CAR30037.1 - 0.028 14.2 2.1 0.31 10.9 0.1 2.9 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Ninjurin PF04923.12 CAR30037.1 - 0.21 11.5 2.4 3.9 7.5 0.1 3.3 2 1 1 3 3 3 0 Ninjurin DUF5337 PF17272.2 CAR30037.1 - 1.8 8.5 6.6 0.54 10.1 0.1 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5337) Med16 PF11635.8 CAR30038.1 - 7.8e-182 606.1 6.8 9.1e-182 605.9 6.8 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 DDE_Tnp_4 PF13359.6 CAR30039.1 - 3.6e-27 95.0 0.0 6.3e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 CAR30039.1 - 0.066 12.9 0.3 0.14 11.9 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Proteasome PF00227.26 CAR30040.1 - 2.2e-52 177.3 0.0 3e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR30040.1 - 2.2e-12 46.4 0.0 5.3e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Bromodomain PF00439.25 CAR30041.1 - 3e-25 88.1 2.2 6.6e-25 87.0 2.2 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CAR30041.1 - 2.7e-09 37.3 0.0 5.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR30041.1 - 1.8e-06 27.9 0.0 3.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR30041.1 - 0.00036 20.9 0.1 0.00069 20.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Bet_v_1 PF00407.19 CAR30041.1 - 0.009 15.9 0.3 0.019 14.9 0.3 1.5 1 0 0 1 1 1 1 Pathogenesis-related protein Bet v I family FR47 PF08445.10 CAR30041.1 - 0.14 12.1 0.1 0.37 10.8 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein ATG7_N PF16420.5 CAR30042.1 - 2.4e-50 171.9 1.1 2.4e-49 168.6 1.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CAR30042.1 - 3.7e-47 160.8 0.0 5.8e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CAR30042.1 - 0.091 12.8 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 CAR30042.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NMD3 PF04981.13 CAR30043.1 - 2.5e-83 279.3 3.0 4.7e-83 278.4 3.0 1.4 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 CAR30043.1 - 0.12 12.4 6.1 3.9 7.5 0.8 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA VPS11_C PF12451.8 CAR30043.1 - 0.49 10.7 1.7 1.2 9.4 1.7 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal DZR PF12773.7 CAR30043.1 - 0.99 9.5 8.2 32 4.6 8.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon RHH_1 PF01402.21 CAR30043.1 - 2 8.5 4.5 8.3 6.5 0.1 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family FYVE PF01363.21 CAR30043.1 - 6.1 7.1 6.9 6.8 6.9 3.6 2.5 2 1 0 2 2 2 0 FYVE zinc finger NOP19 PF10863.8 CAR30044.1 - 1.6e-48 164.2 8.0 2.2e-48 163.7 8.0 1.2 1 0 0 1 1 1 1 Nucleolar protein 19 DUF3188 PF11384.8 CAR30044.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DEAD PF00270.29 CAR30045.1 - 1.7e-42 145.2 0.3 6.6e-42 143.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30045.1 - 3.7e-31 107.8 0.5 1.9e-30 105.5 0.4 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30045.1 - 0.0013 18.8 0.0 0.0053 16.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CNOT1_CAF1_bind PF16415.5 CAR30045.1 - 0.061 12.7 0.9 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 CAF1-binding domain GTP1_OBG PF01018.22 CAR30046.1 - 1.4e-36 125.4 0.8 6.5e-27 94.0 0.7 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CAR30046.1 - 2.3e-20 72.8 0.0 4.4e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR30046.1 - 8.6e-12 44.9 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 CAR30046.1 - 2.1e-09 37.1 0.0 8.5e-09 35.1 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR30046.1 - 0.017 14.7 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 CAR30046.1 - 0.019 14.0 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 CAR30046.1 - 0.031 13.9 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 CAR30046.1 - 0.073 12.5 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CAR30046.1 - 0.099 12.7 0.0 1.5 8.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family THP2 PF09432.10 CAR30047.1 - 3.4e-40 137.1 2.6 3.4e-40 137.1 2.6 2.0 2 1 0 2 2 2 1 Tho complex subunit THP2 DUF3287 PF11690.8 CAR30047.1 - 0.041 13.6 0.2 0.12 12.1 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3287) Utp12 PF04003.12 CAR30047.1 - 0.37 11.1 2.6 3 8.2 0.1 3.0 2 2 1 3 3 3 0 Dip2/Utp12 Family Syntaxin-6_N PF09177.11 CAR30047.1 - 1 10.0 4.8 0.35 11.4 0.7 2.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal ANAPC8 PF04049.13 CAR30048.1 - 1.9e-39 134.9 4.8 1.9e-39 134.9 4.8 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 CAR30048.1 - 1.8e-24 84.5 16.6 1.9e-05 24.3 0.0 8.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 CAR30048.1 - 1.4e-21 74.9 21.9 3.2e-05 23.8 0.0 9.2 11 1 0 11 11 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAR30048.1 - 3.9e-21 73.4 19.3 0.00065 19.6 0.1 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAR30048.1 - 5.9e-14 51.6 0.5 0.00081 20.0 0.0 6.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAR30048.1 - 3.4e-13 49.0 3.6 1.3e-08 34.4 0.0 4.4 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 CAR30048.1 - 2.3e-09 37.7 0.0 5.5e-06 26.9 0.0 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAR30048.1 - 4.8e-09 36.0 2.4 0.0043 17.3 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAR30048.1 - 3.3e-08 33.0 7.6 0.0045 16.9 0.1 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR30048.1 - 4e-06 27.0 10.3 0.0012 19.1 0.1 4.6 3 2 3 6 6 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 CAR30048.1 - 5.2e-05 22.6 3.5 0.027 13.7 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.10 CAR30048.1 - 0.00025 20.2 0.0 0.00092 18.3 0.0 1.9 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 CAR30048.1 - 0.0035 17.8 2.6 1.8 9.1 0.0 4.7 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR30048.1 - 0.0074 16.4 0.0 3.3 7.9 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR30048.1 - 0.024 14.9 21.9 0.064 13.5 1.8 5.2 2 1 3 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 CAR30048.1 - 0.06 13.0 3.3 0.12 12.1 0.8 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 CAR30048.1 - 0.48 10.4 5.9 25 4.9 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAR30048.1 - 1.2 9.9 12.8 27 5.7 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat PROCN PF08083.11 CAR30049.1 - 9e-222 736.0 10.6 1.3e-221 735.5 10.6 1.2 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CAR30049.1 - 8e-122 405.2 0.7 1.4e-121 404.3 0.7 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CAR30049.1 - 6e-84 279.8 0.9 6e-84 279.8 0.9 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CAR30049.1 - 2.7e-80 267.7 1.6 5.9e-80 266.6 1.6 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CAR30049.1 - 9.6e-70 232.9 0.0 2.1e-69 231.8 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CAR30049.1 - 9.4e-47 157.3 0.2 2.7e-46 155.9 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CAR30049.1 - 3.4e-46 156.2 0.0 9.7e-46 154.7 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 CAR30049.1 - 0.039 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Dna2 PF08696.11 CAR30051.1 - 3.6e-56 190.2 0.0 6.8e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 CAR30051.1 - 1.4e-51 174.9 0.0 3.2e-51 173.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR30051.1 - 1.3e-29 103.8 2.5 3.3e-15 56.6 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 CAR30051.1 - 2.6e-13 50.1 0.0 9.9e-13 48.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAR30051.1 - 1.1e-10 42.0 0.0 2.1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAR30051.1 - 6.7e-08 32.6 0.6 0.042 13.6 0.1 4.1 2 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CAR30051.1 - 0.0022 17.9 0.0 0.0066 16.3 0.0 1.8 1 0 0 1 1 1 1 Helicase NTPase_1 PF03266.15 CAR30051.1 - 0.0031 17.5 0.9 0.36 10.7 0.2 2.8 2 0 0 2 2 2 1 NTPase DUF2075 PF09848.9 CAR30051.1 - 0.0038 16.5 0.0 0.018 14.3 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 CAR30051.1 - 0.0078 16.8 0.4 0.029 14.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain UvrD-helicase PF00580.21 CAR30051.1 - 0.012 15.2 0.0 0.03 13.8 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 CAR30051.1 - 0.013 14.7 0.0 0.42 9.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_16 PF13191.6 CAR30051.1 - 0.013 15.9 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RNA_pol_Rpc34 PF05158.12 CAR30051.1 - 0.022 14.2 0.0 0.071 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit AAA_22 PF13401.6 CAR30051.1 - 0.028 14.7 0.1 0.84 9.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain Cas_Cas4 PF01930.17 CAR30051.1 - 0.032 14.3 0.0 0.21 11.7 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function DUF83 MobB PF03205.14 CAR30051.1 - 0.035 14.0 0.2 0.08 12.8 0.2 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 CAR30051.1 - 0.054 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 CAR30051.1 - 0.08 12.8 0.3 0.27 11.1 0.0 2.1 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain SRP54 PF00448.22 CAR30051.1 - 0.092 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CAR30051.1 - 0.096 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAR30051.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CAR30051.1 - 0.11 12.2 0.1 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 CAR30051.1 - 0.18 11.6 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 CAR30051.1 - 1.5 8.8 4.9 1.1 9.3 0.1 2.9 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit RRM_1 PF00076.22 CAR30052.1 - 8.3e-32 108.8 0.1 4.8e-15 55.1 0.0 4.8 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR30052.1 - 0.047 13.8 0.3 9.8 6.4 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif HSF_DNA-bind PF00447.17 CAR30053.1 - 1e-20 74.1 0.0 2e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Glucosamine_iso PF01182.20 CAR30054.1 - 3.1e-61 207.1 0.0 3.8e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MPC PF03650.13 CAR30055.1 - 1.5e-47 160.3 0.0 1.7e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ATP-grasp_2 PF08442.10 CAR30056.1 - 9.7e-74 247.3 2.2 1.9e-73 246.3 2.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CAR30056.1 - 6.8e-26 90.9 2.6 6.4e-25 87.7 0.1 3.2 3 1 1 4 4 4 1 CoA-ligase ATP-grasp_5 PF13549.6 CAR30056.1 - 1.9e-07 30.8 0.7 3.1e-07 30.1 0.7 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CAR30056.1 - 0.0012 18.7 0.8 0.0038 17.0 0.2 2.1 1 1 2 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pre-PUA PF17832.1 CAR30056.1 - 0.13 12.9 0.0 0.5 11.1 0.0 2.0 2 0 0 2 2 2 0 Pre-PUA-like domain SDA1 PF05285.12 CAR30057.1 - 3.5e-86 289.8 47.6 1.2e-85 288.0 42.3 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 CAR30057.1 - 1.3e-20 73.5 0.0 3.7e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 NUC130/3NT domain TFIIB PF00382.19 CAR30058.1 - 2e-57 191.1 0.9 1.6e-28 98.6 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CAR30058.1 - 1.2e-27 96.2 0.7 1.2e-27 96.2 0.7 2.7 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CAR30058.1 - 2.9e-12 45.9 3.4 5.5e-12 45.0 3.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CAR30058.1 - 7.6e-05 22.5 0.2 0.12 12.1 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain RNA_polI_A14 PF08203.11 CAR30058.1 - 0.3 11.8 2.2 0.93 10.3 0.1 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 A2L_zn_ribbon PF08792.10 CAR30058.1 - 0.68 9.7 4.7 2.1 8.1 4.7 1.8 1 1 0 1 1 1 0 A2L zinc ribbon domain CPDase PF07823.11 CAR30059.1 - 5.1e-73 245.0 0.0 5.7e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 CAR30059.1 - 0.0015 18.4 0.0 0.004 17.1 0.0 1.6 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily MDM10 PF12519.8 CAR30059.1 - 0.076 11.9 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Fungal_trans_2 PF11951.8 CAR30060.1 - 1.8e-79 267.3 0.2 2.4e-79 266.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR30060.1 - 5.5e-07 29.6 10.9 9.4e-07 28.9 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 CAR30060.1 - 1.6 9.3 10.8 3.8 8.0 10.8 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region PRELI PF04707.14 CAR30061.1 - 1.9e-43 148.0 0.1 2.2e-43 147.8 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Chorion_3 PF05387.11 CAR30062.1 - 1.4 8.5 11.5 0.062 12.9 6.0 1.6 2 0 0 2 2 2 0 Chorion family 3 PH_RBD PF12068.8 CAR30062.1 - 4 6.9 10.3 0.74 9.3 6.4 1.7 1 1 0 2 2 2 0 Rab-binding domain (RBD) NMT PF01233.19 CAR30063.1 - 1e-76 256.2 0.4 1.2e-75 252.7 0.1 2.3 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CAR30063.1 - 1.8e-76 256.3 0.1 2.7e-76 255.7 0.1 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 CAR30063.1 - 0.0013 18.9 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF1576 PF07613.11 CAR30063.1 - 0.24 10.9 0.0 14 5.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) WD40 PF00400.32 CAR30064.1 - 2.4e-11 44.0 12.1 0.0019 19.0 0.3 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 CAR30064.1 - 0.0002 20.1 0.4 0.0036 16.0 0.2 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 CAR30064.1 - 0.084 13.4 0.0 2 9.0 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain DUF2357 PF09823.9 CAR30065.1 - 0.087 12.1 0.2 0.11 11.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Nop PF01798.18 CAR30066.1 - 2.7e-85 285.5 0.0 2.7e-85 285.5 0.0 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CAR30066.1 - 8.3e-20 70.9 0.1 8.3e-20 70.9 0.1 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RR_TM4-6 PF06459.12 CAR30066.1 - 1.2 8.9 23.1 1.8 8.3 23.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 CAR30066.1 - 2.8 6.4 11.4 3.8 5.9 11.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_polI_A34 PF08208.11 CAR30066.1 - 2.8 8.0 44.9 5.4 7.1 44.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.12 CAR30066.1 - 4.7 7.4 17.7 7.2 6.8 17.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family MCM_bind PF09739.9 CAR30066.1 - 4.8 5.5 16.6 6.3 5.1 16.6 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor POC1 PF10450.9 CAR30067.1 - 2.5e-50 171.0 0.0 3e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 POC1 chaperone ig PF00047.25 CAR30067.1 - 0.051 13.7 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin domain Prefoldin_2 PF01920.20 CAR30068.1 - 2.7e-20 72.3 12.2 3.1e-20 72.1 12.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.6 CAR30068.1 - 0.001 18.8 8.7 0.0055 16.5 2.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) DUF1192 PF06698.11 CAR30068.1 - 0.21 11.6 0.2 0.21 11.6 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Spc24 PF08286.11 CAR30068.1 - 1.3 9.4 10.8 0.75 10.1 1.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Bcr-Abl_Oligo PF09036.10 CAR30068.1 - 2.8 8.0 5.6 1.3 9.0 1.3 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain COQ9 PF08511.11 CAR30069.1 - 4.1e-22 77.7 0.9 5.2e-22 77.4 0.1 1.6 2 0 0 2 2 2 1 COQ9 ADH_N PF08240.12 CAR30070.1 - 2.6e-25 88.4 3.4 2.6e-25 88.4 3.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR30070.1 - 3.4e-20 72.4 0.4 9.2e-20 71.0 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CAR30070.1 - 0.021 14.1 1.2 0.036 13.4 1.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CAR30070.1 - 0.029 13.7 0.1 0.049 13.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CAR30070.1 - 0.032 13.8 0.2 0.052 13.1 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 CAR30070.1 - 0.036 14.3 0.0 0.07 13.4 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CAR30070.1 - 0.13 12.6 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain HycI PF01750.18 CAR30070.1 - 0.18 11.7 0.2 0.32 10.8 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase maturation protease zf-RanBP PF00641.18 CAR30071.1 - 4.7e-21 73.8 13.1 5.8e-11 41.5 2.4 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CAR30071.1 - 2e-09 37.2 0.0 0.00052 19.8 0.0 2.5 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc-ribbon_6 PF10005.9 CAR30071.1 - 0.039 14.6 3.3 1 10.1 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain RRM_7 PF16367.5 CAR30071.1 - 0.12 12.5 0.1 0.55 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif Vps36-NZF-N PF16988.5 CAR30071.1 - 0.71 9.3 8.9 5.8 6.4 0.9 3.2 2 1 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-ribbon_3 PF13248.6 CAR30071.1 - 3.9 7.0 5.2 0.66 9.5 0.6 2.1 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 CAR30071.1 - 4.6 7.4 9.8 14 5.8 2.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon AAA_18 PF13238.6 CAR30072.1 - 1.4e-30 106.5 0.2 3e-30 105.4 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR30072.1 - 1.7e-05 25.3 0.0 3e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 CAR30072.1 - 2.6e-05 24.7 0.1 0.00016 22.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 CAR30072.1 - 0.00052 20.4 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAR30072.1 - 0.00056 20.2 0.1 0.0016 18.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR30072.1 - 0.0012 19.1 0.1 0.0021 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR30072.1 - 0.0023 18.3 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.12 CAR30072.1 - 0.0039 16.5 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin dNK PF01712.19 CAR30072.1 - 0.0063 16.4 0.2 3.8 7.3 0.1 2.5 1 1 1 3 3 3 2 Deoxynucleoside kinase NTPase_1 PF03266.15 CAR30072.1 - 0.015 15.3 0.0 0.036 14.0 0.0 1.6 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 CAR30072.1 - 0.018 14.7 0.1 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 CAR30072.1 - 0.031 14.3 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CAR30072.1 - 0.034 14.3 0.1 5.4 7.2 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 CAR30072.1 - 0.037 14.4 0.0 0.096 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CAR30072.1 - 0.044 13.5 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 CAR30072.1 - 0.044 13.2 0.0 0.091 12.2 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_7 PF12775.7 CAR30072.1 - 0.093 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NOT2_3_5 PF04153.18 CAR30073.1 - 1.3e-30 106.2 0.5 1.6e-30 105.9 0.5 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family zf-Mss51 PF13824.6 CAR30074.1 - 3e-16 59.2 0.4 1.8e-15 56.8 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 CAR30074.1 - 0.0064 16.2 0.4 0.0064 16.2 0.4 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain DUF1713 PF08213.11 CAR30075.1 - 5.6e-12 45.4 22.2 8.3e-12 44.8 22.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) SAP25 PF15476.6 CAR30075.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Peptidase_S49_N PF08496.10 CAR30075.1 - 2.7 8.0 6.4 3.2 7.8 6.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Heme_oxygenase PF01126.20 CAR30076.1 - 8.5e-15 55.1 1.2 2.7e-14 53.4 1.2 1.9 1 1 0 1 1 1 1 Heme oxygenase Med4 PF10018.9 CAR30076.1 - 0.08 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DNA_ligase_A_M PF01068.21 CAR30077.1 - 5.2e-61 205.9 0.0 7.7e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CAR30077.1 - 6.8e-43 147.0 0.9 1.4e-42 145.9 0.1 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CAR30077.1 - 5.8e-25 87.8 0.0 1.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region ENTH PF01417.20 CAR30078.1 - 4.7e-43 146.2 0.0 1.2e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 ENTH domain CENP-X PF09415.10 CAR30079.1 - 1.4e-24 86.2 0.5 1.6e-24 86.0 0.5 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X Dynactin_p62 PF05502.13 CAR30080.1 - 7.9e-12 44.7 18.4 6.1e-05 22.0 0.0 2.2 1 1 0 2 2 2 2 Dynactin p62 family UPF0547 PF10571.9 CAR30080.1 - 0.9 9.7 8.3 1.7 8.8 0.1 3.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Prok-RING_2 PF14445.6 CAR30080.1 - 1.3 9.2 12.0 0.26 11.5 7.3 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Zn-ribbon_8 PF09723.10 CAR30080.1 - 2 8.6 0.0 2 8.6 0.0 4.1 3 1 0 3 3 3 0 Zinc ribbon domain zf-Mss51 PF13824.6 CAR30080.1 - 2.1 8.5 8.8 7.4 6.7 0.1 2.9 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sel1 PF08238.12 CAR30081.1 - 3.8e-19 68.7 9.0 0.00016 22.3 0.0 8.3 8 0 0 8 8 8 5 Sel1 repeat TPR_7 PF13176.6 CAR30081.1 - 0.016 15.2 6.6 2.5 8.3 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR30081.1 - 0.11 13.2 0.4 0.11 13.2 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR30081.1 - 0.31 11.2 0.1 0.31 11.2 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR30081.1 - 1.5 8.8 8.4 0.5 10.3 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 CAR30082.1 - 2.9e-19 69.1 16.1 0.0011 19.7 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30082.1 - 2.8e-06 27.5 4.1 0.044 14.1 0.1 4.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 CAR30082.1 - 0.021 15.1 0.4 5.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Kelch motif TFIIIC_delta PF12657.7 CAR30082.1 - 0.027 14.4 2.0 0.087 12.7 2.0 2.0 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term YmzC PF14157.6 CAR30082.1 - 0.094 12.8 0.0 1.6 8.9 0.0 2.8 3 0 0 3 3 3 0 YmzC-like protein PNP_UDP_1 PF01048.20 CAR30083.1 - 7.7e-49 166.0 0.0 9e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DEAD PF00270.29 CAR30084.1 - 1e-43 149.1 0.0 1.6e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30084.1 - 5.8e-30 103.9 0.4 9.2e-29 100.0 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CAR30084.1 - 0.0029 16.8 0.1 0.0029 16.8 0.1 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Arcadin_1 PF18653.1 CAR30084.1 - 0.11 12.6 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Arcadin 1 Pkinase PF00069.25 CAR30085.1 - 9.4e-65 218.6 0.0 1.2e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30085.1 - 3.6e-38 131.3 0.0 5.4e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR30085.1 - 0.00084 18.4 0.0 0.0015 17.6 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAR30085.1 - 0.0011 18.3 0.0 0.0043 16.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAR30085.1 - 0.0015 17.4 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Mrpl_C PF18502.1 CAR30085.1 - 0.085 13.1 0.3 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain WD40 PF00400.32 CAR30087.1 - 3.6e-06 27.6 4.9 0.087 13.7 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30087.1 - 0.003 17.8 0.0 0.15 12.4 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 CAR30089.1 - 1e-16 60.7 0.5 2.2e-16 59.6 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR30089.1 - 1.3e-05 25.2 9.1 2.5e-05 24.3 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 CAR30090.1 - 1.7e-44 150.6 0.4 3.1e-44 149.8 0.4 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR30090.1 - 4.8e-35 120.2 0.2 1.8e-34 118.4 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sas10 PF09368.10 CAR30091.1 - 7.3e-28 96.9 12.5 2.6e-27 95.1 12.5 2.0 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CAR30091.1 - 3.8e-07 30.6 0.1 2e-06 28.3 0.1 2.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RNA_pol_Rpc4 PF05132.14 CAR30092.1 - 8.4e-33 113.9 2.5 8.4e-33 113.9 2.5 2.8 3 0 0 3 3 3 1 RNA polymerase III RPC4 APG9 PF04109.16 CAR30093.1 - 1.2e-199 664.3 19.1 1.4e-199 664.1 19.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Nop14 PF04147.12 CAR30094.1 - 5.5e-181 603.9 64.1 1.2e-96 324.9 10.1 2.0 1 1 1 2 2 2 2 Nop14-like family Bromo_TP PF07524.13 CAR30094.1 - 0.15 12.0 0.1 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Bromodomain associated TraN PF06986.11 CAR30094.1 - 0.89 9.2 3.8 18 4.9 0.9 2.4 2 0 0 2 2 2 0 Type-1V conjugative transfer system mating pair stabilisation PCI PF01399.27 CAR30095.1 - 6.4e-23 81.3 3.6 8.7e-23 80.8 0.0 3.0 3 1 0 3 3 3 1 PCI domain RPN5_C PF18098.1 CAR30095.1 - 6e-14 51.9 3.3 6e-14 51.9 3.3 2.5 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN5 C-terminal domain Spc24 PF08286.11 CAR30095.1 - 0.17 12.1 6.3 1 9.6 5.6 2.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 CAR30095.1 - 7.3 7.1 8.0 0.95 10.0 1.7 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CCDC85 PF10226.9 CAR30096.1 - 0.012 15.3 1.6 0.037 13.7 1.0 2.0 2 0 0 2 2 2 0 CCDC85 family SOAR PF16533.5 CAR30096.1 - 0.014 15.4 0.4 0.014 15.4 0.4 2.0 2 0 0 2 2 2 0 STIM1 Orai1-activating region COMP PF11598.8 CAR30096.1 - 0.071 13.6 0.4 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Ax_dynein_light PF10211.9 CAR30096.1 - 0.48 10.3 10.1 0.053 13.5 3.7 2.1 2 0 0 2 2 2 0 Axonemal dynein light chain DivIC PF04977.15 CAR30096.1 - 1.5 8.7 9.4 0.19 11.5 1.6 2.6 2 2 1 3 3 3 0 Septum formation initiator YabA PF06156.13 CAR30096.1 - 1.8 9.2 6.7 2.1 9.1 2.8 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DHR10 PF18595.1 CAR30096.1 - 2.3 8.3 12.1 0.23 11.5 4.4 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain PKK PF12474.8 CAR30096.1 - 7.3 6.7 13.3 0.89 9.7 3.4 2.4 2 1 0 2 2 2 0 Polo kinase kinase DUF2013 PF09431.10 CAR30097.1 - 1.8e-40 138.3 13.2 5e-40 136.9 13.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) BAG PF02179.16 CAR30097.1 - 0.022 15.2 0.3 0.064 13.7 0.3 1.9 1 0 0 1 1 1 0 BAG domain Bromo_TP_like PF17027.5 CAR30097.1 - 0.21 11.8 10.6 0.1 12.7 1.3 3.2 2 1 1 3 3 3 0 Histone-fold protein Tubulin PF00091.25 CAR30098.1 - 9.5e-67 225.0 0.0 1.6e-66 224.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAR30098.1 - 1.3e-22 80.3 0.0 3e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CAR30098.1 - 8.3e-07 29.3 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CAR30098.1 - 0.0074 16.0 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Coatomer_WDAD PF04053.14 CAR30099.1 - 1.1e-127 426.8 4.3 1.6e-127 426.2 4.3 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CAR30099.1 - 1.8e-74 251.0 0.0 2.5e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CAR30099.1 - 1.4e-38 130.2 22.0 2.1e-07 31.5 0.1 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30099.1 - 4.2e-13 49.4 1.0 2.5e-05 24.5 0.0 6.7 4 2 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR30099.1 - 0.00012 20.9 6.8 0.37 9.4 0.1 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Glyco_hydro_16 PF00722.21 CAR30100.1 - 2.2e-41 141.3 0.0 3.6e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 CAR30100.1 - 1.9 9.0 12.4 3.9 8.0 12.4 1.4 1 0 0 1 1 1 0 Chitin recognition protein Ferric_reduct PF01794.19 CAR30101.1 - 4.5e-23 81.7 17.2 4.7e-23 81.7 13.9 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CAR30101.1 - 2.7e-17 62.8 0.0 5.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CAR30101.1 - 2.3e-15 57.1 0.0 5.4e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CAR30101.1 - 0.098 13.3 0.0 0.42 11.3 0.0 2.0 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CFEM PF05730.11 CAR30101.1 - 0.24 11.5 0.5 0.49 10.5 0.5 1.5 1 0 0 1 1 1 0 CFEM domain D123 PF07065.14 CAR30102.1 - 9.3e-109 363.3 1.5 1.1e-108 363.0 1.5 1.1 1 0 0 1 1 1 1 D123 Cpn60_TCP1 PF00118.24 CAR30103.1 - 2.1e-147 491.7 13.7 2.4e-147 491.5 13.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CDP-OH_P_transf PF01066.21 CAR30104.1 - 1.7e-15 57.6 0.6 4.4e-15 56.2 0.6 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase BPL_N PF09825.9 CAR30105.1 - 1.9e-122 409.0 0.0 2.5e-122 408.6 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CAR30105.1 - 2.3e-22 79.3 0.0 9.1e-22 77.4 0.0 2.1 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CAR30105.1 - 2.1e-12 46.7 0.8 3.8e-12 45.9 0.1 1.8 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain RNA_pol_Rpb1_1 PF04997.12 CAR30106.1 - 2.5e-114 381.8 0.0 4.7e-114 380.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CAR30106.1 - 2.2e-106 355.2 0.1 3.4e-106 354.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CAR30106.1 - 2.8e-78 261.9 0.0 9.5e-78 260.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CAR30106.1 - 7.1e-64 215.2 2.2 1.9e-63 213.8 2.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CAR30106.1 - 3.8e-48 162.9 4.2 9.4e-48 161.6 4.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CAR30106.1 - 1e-46 158.8 0.0 2.8e-46 157.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CAR30106.1 - 1.8e-35 121.1 0.1 4.5e-35 119.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CAR30106.1 - 2.4e-11 43.4 333.6 0.1 13.0 16.1 15.3 15 0 0 15 15 15 14 RNA polymerase Rpb1 C-terminal repeat Pro_isomerase PF00160.21 CAR30107.1 - 1.2e-42 145.8 0.0 1.9e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 CAR30107.1 - 1.7e-11 43.4 0.0 9.2e-06 25.3 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR30107.1 - 6.4e-10 38.4 0.0 0.0012 18.8 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR30107.1 - 2.3e-06 27.9 0.3 0.15 12.7 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR30107.1 - 1.2e-05 25.1 0.1 0.02 15.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR30107.1 - 2.4e-05 24.5 0.1 0.0073 16.6 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR30107.1 - 0.0022 18.6 0.0 0.013 16.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR30107.1 - 0.022 14.9 0.1 0.084 13.0 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR30107.1 - 0.11 12.9 0.3 1.4 9.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR30107.1 - 0.19 11.8 0.5 12 6.2 0.4 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAR30107.1 - 0.74 9.5 3.9 3.1 7.6 0.4 3.3 4 0 0 4 4 4 0 TPR repeat Scm3 PF10384.9 CAR30108.1 - 1.5e-21 75.9 0.9 3.9e-21 74.5 0.2 2.1 2 0 0 2 2 2 1 Centromere protein Scm3 CHCH PF06747.13 CAR30109.1 - 0.0015 18.6 3.9 0.0015 18.6 3.9 2.1 2 0 0 2 2 2 1 CHCH domain Complex1_49kDa PF00346.19 CAR30109.1 - 0.042 13.0 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF5363 PF17320.2 CAR30109.1 - 0.046 13.6 1.9 0.28 11.1 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5363) CbiK PF06180.11 CAR30109.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Sec31 PF11549.8 CAR30110.1 - 2e-26 91.6 5.5 7.6e-26 89.8 5.5 2.1 1 0 0 1 1 1 1 Protein transport protein SEC31 WD40 PF00400.32 CAR30110.1 - 5.4e-11 42.9 3.4 0.94 10.5 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30110.1 - 1.1e-08 35.2 0.1 0.29 11.5 0.0 4.6 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 CAR30110.1 - 1.3e-06 28.3 4.5 2.6e-06 27.3 0.0 3.5 3 1 1 4 4 4 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 CAR30110.1 - 8.3e-06 25.7 0.9 2e-05 24.4 0.9 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 CAR30110.1 - 0.00031 20.8 0.1 0.00092 19.3 0.1 1.8 1 1 0 1 1 1 1 Prp18 domain Sugar_tr PF00083.24 CAR30111.1 - 1.7e-121 406.3 29.4 2.2e-121 405.9 29.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30111.1 - 1.9e-17 63.2 37.2 1.3e-13 50.7 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Prenyltransf PF01255.19 CAR30112.1 - 0.041 13.4 0.0 0.18 11.3 0.0 1.9 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 CAR30112.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Mg_chelatase_C PF13335.6 CAR30112.1 - 0.19 12.4 0.7 0.56 10.9 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Arf PF00025.21 CAR30113.1 - 4.2e-79 264.0 0.0 5e-79 263.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CAR30113.1 - 7.1e-15 54.9 0.0 8.7e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CAR30113.1 - 3.4e-14 53.1 0.0 4.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CAR30113.1 - 8.2e-14 51.5 1.1 4.3e-10 39.3 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CAR30113.1 - 1e-13 51.2 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CAR30113.1 - 3.7e-11 42.8 0.0 4.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR30113.1 - 7.8e-06 26.0 0.2 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR30113.1 - 0.0055 16.6 0.1 0.8 9.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRP54 PF00448.22 CAR30113.1 - 0.0075 15.9 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain cobW PF02492.19 CAR30113.1 - 0.0079 15.8 0.2 2.3 7.8 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CAR30113.1 - 0.033 14.4 0.3 0.054 13.7 0.3 1.6 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CAR30113.1 - 0.055 12.7 1.2 2 7.6 0.1 2.0 1 1 1 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 CAR30113.1 - 0.072 13.0 0.5 6.8 6.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 CAR30113.1 - 0.11 12.2 1.1 0.97 9.1 0.3 2.0 2 0 0 2 2 2 0 Thymidylate kinase 6PF2K PF01591.18 CAR30113.1 - 0.12 11.7 1.1 0.55 9.5 1.1 1.9 1 1 0 1 1 1 0 6-phosphofructo-2-kinase ABC_tran PF00005.27 CAR30113.1 - 0.18 12.3 0.3 0.35 11.4 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Arf PF00025.21 CAR30114.1 - 1.2e-79 265.8 0.0 1.4e-79 265.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CAR30114.1 - 5.6e-15 55.2 0.0 6.8e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CAR30114.1 - 2e-14 53.8 0.0 2.7e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CAR30114.1 - 9e-14 51.4 0.0 9.7e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAR30114.1 - 2.4e-13 50.0 1.4 1e-09 38.0 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAR30114.1 - 6.2e-11 42.1 0.0 7.8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR30114.1 - 1.1e-05 25.4 0.0 1.8e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CAR30114.1 - 0.0068 16.0 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 CAR30114.1 - 0.0092 15.9 0.1 1.5 8.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CAR30114.1 - 0.02 14.5 0.2 5.8 6.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CAR30114.1 - 0.042 14.0 0.3 0.062 13.5 0.3 1.6 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CAR30114.1 - 0.054 12.8 1.4 0.42 9.9 1.4 2.0 1 1 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.12 CAR30114.1 - 0.1 12.5 0.6 9.2 6.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 CAR30114.1 - 0.16 12.5 0.2 0.23 12.0 0.2 1.4 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CAR30114.1 - 0.19 11.4 1.0 0.97 9.1 0.3 2.0 2 0 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.27 CAR30114.1 - 0.2 12.1 0.3 0.4 11.2 0.3 1.7 1 1 0 1 1 1 0 ABC transporter Ribosomal_L29 PF00831.23 CAR30115.1 - 9.1e-16 57.6 2.4 9.1e-16 57.6 2.4 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein PilJ PF13675.6 CAR30115.1 - 0.027 14.5 1.9 0.039 14.0 0.9 1.7 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term AA_permease_N PF08403.10 CAR30115.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal Ufd2P_core PF10408.9 CAR30116.1 - 3e-205 683.5 9.6 4.2e-205 683.0 9.6 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CAR30116.1 - 5.9e-29 100.0 0.9 1.6e-28 98.7 0.9 1.8 1 0 0 1 1 1 1 U-box domain Cnd1_N PF12922.7 CAR30116.1 - 0.074 12.9 0.7 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Med4 PF10018.9 CAR30116.1 - 0.12 12.1 0.1 7.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 R3H PF01424.22 CAR30117.1 - 2.1e-10 40.4 0.0 5.1e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 R3H domain Vfa1 PF08432.10 CAR30117.1 - 5.3 7.3 8.8 2.3 8.5 3.8 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Rho_GDI PF02115.17 CAR30118.1 - 2.2e-62 210.3 2.9 2.5e-62 210.1 2.9 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor OHCU_decarbox PF09349.10 CAR30119.1 - 5e-40 137.5 0.2 5.7e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Metallophos PF00149.28 CAR30120.1 - 7.4e-34 118.0 0.3 1.2e-33 117.4 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NUDE_C PF04880.13 CAR30121.1 - 0.082 13.4 1.8 0.13 12.7 1.8 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ATP-synt_ab PF00006.25 CAR30122.1 - 5.2e-117 389.0 0.0 7.1e-117 388.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CAR30122.1 - 9e-45 151.5 0.0 1.7e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CAR30122.1 - 9e-16 58.2 2.3 2.3e-15 56.9 2.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.6 CAR30122.1 - 0.094 12.7 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mit_KHE1 PF10173.9 CAR30123.1 - 8.7e-57 192.3 3.0 1.1e-56 192.0 3.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related HA PF03457.14 CAR30124.1 - 0.021 15.1 2.2 0.048 14.0 2.2 1.6 1 0 0 1 1 1 0 Helicase associated domain MARVEL PF01284.23 CAR30124.1 - 0.15 12.1 2.9 0.24 11.4 2.9 1.3 1 0 0 1 1 1 0 Membrane-associating domain Cullin PF00888.22 CAR30125.1 - 2.1e-149 499.0 7.9 2.6e-149 498.7 7.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CAR30125.1 - 5.2e-23 80.9 3.3 6.6e-23 80.5 0.9 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain ANAPC4 PF12896.7 CAR30125.1 - 0.003 17.1 1.5 0.019 14.5 1.4 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF919 PF06034.11 CAR30125.1 - 0.074 12.9 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Penicillinase_R PF03965.16 CAR30125.1 - 0.13 12.7 2.3 2.3 8.6 0.0 3.2 3 0 0 3 3 3 0 Penicillinase repressor DnaI_N PF07319.11 CAR30125.1 - 4.6 8.0 5.8 41 4.9 0.2 3.8 4 0 0 4 4 4 0 Primosomal protein DnaI N-terminus HMGL-like PF00682.19 CAR30126.1 - 4.8e-85 285.3 0.2 6.9e-85 284.8 0.2 1.2 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 CAR30126.1 - 0.13 12.9 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain WD40 PF00400.32 CAR30127.1 - 7e-07 29.8 6.0 0.071 14.0 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat IATP PF04568.12 CAR30128.1 - 3.8e-14 52.9 1.1 4.8e-14 52.6 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP PspB PF06667.12 CAR30128.1 - 0.11 12.5 1.6 0.16 12.0 1.6 1.2 1 0 0 1 1 1 0 Phage shock protein B DUF1943 PF09172.11 CAR30128.1 - 0.12 11.6 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DIRP PF06584.13 CAR30128.1 - 0.26 11.5 3.0 0.43 10.8 3.0 1.4 1 0 0 1 1 1 0 DIRP DUF1003 PF06210.11 CAR30128.1 - 0.3 11.2 1.7 0.43 10.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) MTCP1 PF08991.10 CAR30129.1 - 3.2e-27 94.5 6.1 3.9e-27 94.3 6.1 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 CAR30129.1 - 0.0064 16.6 5.0 0.0064 16.6 5.0 1.5 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.10 CAR30129.1 - 0.13 12.3 5.1 0.36 10.9 1.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36e PF01158.18 CAR30131.1 - 2.5e-36 123.8 3.1 2.8e-36 123.7 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L28 PF00830.19 CAR30132.1 - 3.2e-18 65.7 0.8 5.7e-18 64.9 0.8 1.4 1 0 0 1 1 1 1 Ribosomal L28 family RabGAP-TBC PF00566.18 CAR30133.1 - 3.3e-48 164.2 0.0 8.4e-48 162.9 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DivIC PF04977.15 CAR30133.1 - 0.0025 17.5 18.9 0.31 10.9 1.6 3.7 2 1 1 3 3 3 3 Septum formation initiator DUF1192 PF06698.11 CAR30133.1 - 0.075 13.1 6.5 0.14 12.3 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ADIP PF11559.8 CAR30133.1 - 0.15 12.1 16.2 0.77 9.8 8.2 2.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Phlebovirus_NSM PF07246.11 CAR30133.1 - 0.17 11.3 11.4 0.057 12.8 4.3 2.3 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M HALZ PF02183.18 CAR30133.1 - 0.3 11.3 19.6 0.27 11.5 0.7 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 CAR30133.1 - 1 9.5 18.6 0.67 10.1 10.7 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 PLAC9 PF15205.6 CAR30134.1 - 0.04 14.3 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 Placenta-specific protein 9 Fungal_trans PF04082.18 CAR30135.1 - 2.6e-16 59.4 0.1 6e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 CAR30135.1 - 1.2e-10 41.3 0.1 3e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 CAR30135.1 - 2.5e-09 37.1 13.7 4.3e-09 36.4 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HutD PF05962.11 CAR30135.1 - 0.064 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 HutD Peptidase_C50 PF03568.17 CAR30135.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C50 RQC PF09382.10 CAR30136.1 - 1e-28 99.4 0.1 2.1e-28 98.4 0.1 1.5 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 CAR30136.1 - 6.8e-23 81.1 0.1 2.3e-18 66.6 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 CAR30136.1 - 6.1e-21 75.0 0.0 1.5e-20 73.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CAR30136.1 - 7.2e-16 58.7 9.4 2.1e-15 57.2 9.4 1.9 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_Sgs1 PF11408.8 CAR30136.1 - 2.8e-09 36.9 0.0 7.1e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Sgs1 RecQ helicase ResIII PF04851.15 CAR30136.1 - 2e-05 24.6 0.0 0.00016 21.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 CAR30136.1 - 0.0019 18.1 0.0 0.0081 16.1 0.0 2.1 1 0 0 1 1 1 1 HRDC domain MFS_1 PF07690.16 CAR30137.1 - 3.9e-27 95.1 9.2 8.2e-27 94.0 6.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GDC-P PF02347.16 CAR30138.1 - 8.4e-203 674.0 0.0 7.9e-188 624.6 0.0 2.1 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CAR30138.1 - 0.00031 19.8 0.0 0.02 13.8 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAR30138.1 - 0.11 11.8 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.32 CAR30139.1 - 1.8e-13 50.7 9.1 0.0011 19.7 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Glyco_hydro_43 PF04616.14 CAR30139.1 - 0.07 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 Herpes_capsid PF06112.11 CAR30139.1 - 2.7 8.0 8.0 5.5 7.0 8.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribosomal_S17 PF00366.20 CAR30140.1 - 1.6e-22 79.4 0.6 3.6e-22 78.2 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 Rhomboid PF01694.22 CAR30141.1 - 7.1e-17 61.8 10.2 7.1e-17 61.8 10.2 1.5 2 0 0 2 2 2 1 Rhomboid family DUF2075 PF09848.9 CAR30142.1 - 1.5e-107 360.0 0.0 2e-107 359.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CAR30142.1 - 5e-09 36.5 0.0 1.8e-08 34.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR30142.1 - 0.00015 22.2 0.0 0.00052 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CAR30142.1 - 0.00041 20.1 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CAR30142.1 - 0.00081 19.8 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CAR30142.1 - 0.0027 17.8 0.1 1.7 8.6 0.0 2.4 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CAR30142.1 - 0.0037 17.1 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CAR30142.1 - 0.0066 16.4 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 CAR30142.1 - 0.0074 16.8 1.0 0.068 13.7 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CAR30142.1 - 0.02 15.3 0.0 0.072 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CAR30142.1 - 0.026 14.5 0.0 0.087 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF3466 PF11949.8 CAR30142.1 - 0.027 13.1 0.0 0.039 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) RsgA_GTPase PF03193.16 CAR30142.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 CAR30142.1 - 0.087 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 CAR30142.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 CAR30142.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin NTPase_1 PF03266.15 CAR30142.1 - 0.13 12.1 0.0 14 5.6 0.0 3.1 3 0 0 3 3 3 0 NTPase UAA PF08449.11 CAR30143.1 - 3.8e-35 121.5 13.0 4.5e-35 121.3 13.0 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CAR30143.1 - 1e-08 35.4 20.5 3.4e-08 33.8 6.3 3.4 1 1 2 3 3 3 2 EamA-like transporter family TPT PF03151.16 CAR30143.1 - 4.2e-08 32.9 5.3 0.0019 17.6 0.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF1433 PF07252.11 CAR30143.1 - 0.084 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) MPS-4 PF17523.2 CAR30143.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.7 3 0 0 3 3 3 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 SRP68 PF16969.5 CAR30144.1 - 5e-63 214.0 9.9 7.4e-63 213.4 9.9 1.3 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Coatomer_g_Cpla PF16381.5 CAR30144.1 - 0.1 12.8 0.5 0.4 10.8 0.1 2.3 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform DUF4302 PF14135.6 CAR30144.1 - 7.5 6.4 7.4 2.6 7.9 0.3 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4302) RINGv PF12906.7 CAR30145.1 - 1.2e-05 25.3 6.2 3.1e-05 24.0 6.2 1.7 1 0 0 1 1 1 1 RING-variant domain DUF3120 PF11318.8 CAR30145.1 - 0.034 14.5 0.3 9.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) FANCL_C PF11793.8 CAR30145.1 - 0.086 13.0 7.6 0.4 10.9 4.0 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain RasGAP_C PF03836.15 CAR30146.1 - 5.9e-23 81.5 8.6 5.9e-23 81.5 8.6 2.5 2 0 0 2 2 2 1 RasGAP C-terminus CH PF00307.31 CAR30146.1 - 3.4e-15 56.2 0.3 1.5e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain RasGAP PF00616.19 CAR30146.1 - 4.3e-14 52.7 2.5 4.4e-14 52.7 0.1 2.3 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Takusan PF04822.13 CAR30146.1 - 0.0045 16.8 2.4 0.037 13.9 1.1 2.9 2 0 0 2 2 2 1 Takusan IQ PF00612.27 CAR30146.1 - 0.015 15.1 11.2 3 7.9 0.1 7.0 8 0 0 8 8 8 0 IQ calmodulin-binding motif Imm71 PF15602.6 CAR30146.1 - 0.19 11.8 2.6 8.7 6.4 0.0 3.0 2 1 1 3 3 3 0 Immunity protein 71 RP-C_C PF11800.8 CAR30146.1 - 0.46 10.5 7.1 0.064 13.3 2.2 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region PHM7_cyt PF14703.6 CAR30146.1 - 1.4 9.2 6.5 1.2 9.4 1.6 3.0 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF1664 PF07889.12 CAR30146.1 - 5.2 7.1 8.3 2.7 8.0 1.8 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF1664) TBCC_N PF16752.5 CAR30147.1 - 0.053 14.0 2.2 0.16 12.4 0.5 2.4 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HSP90 PF00183.18 CAR30148.1 - 1e-219 730.8 31.4 1.4e-219 730.3 31.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CAR30148.1 - 1.5e-14 54.4 0.0 3.2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CAR30148.1 - 8.1e-10 38.7 0.0 2.2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Linocin_M18 PF04454.12 CAR30148.1 - 0.029 13.7 0.7 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 Encapsulating protein for peroxidase Ubiq-assoc PF09145.10 CAR30148.1 - 0.085 12.9 0.2 2.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Ubiquitin-associated DUF1676 PF07898.13 CAR30148.1 - 0.55 10.3 3.0 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Na_trans_assoc PF06512.13 CAR30148.1 - 8.3 6.6 15.0 1.3 9.3 6.0 2.5 2 0 0 2 2 2 0 Sodium ion transport-associated RTP1_C1 PF10363.9 CAR30149.1 - 1.4e-32 112.1 3.1 5.2e-32 110.4 0.2 3.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 CAR30149.1 - 1.8e-05 24.3 0.5 4.4e-05 23.1 0.5 1.8 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 SIL1 PF16782.5 CAR30149.1 - 0.037 13.3 2.3 0.066 12.4 0.1 2.5 2 0 0 2 2 2 0 Nucleotide exchange factor SIL1 PMC2NT PF08066.12 CAR30149.1 - 0.12 13.1 4.5 0.14 12.9 1.0 2.9 3 0 0 3 3 3 0 PMC2NT (NUC016) domain CENP-B_dimeris PF09026.10 CAR30149.1 - 0.55 10.7 5.2 1.7 9.1 5.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ank_2 PF12796.7 CAR30150.1 - 8e-16 58.4 0.0 1.5e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR30150.1 - 1.6e-14 54.0 0.1 2.9e-11 43.7 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR30150.1 - 4.5e-14 52.3 0.3 6e-09 36.0 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CAR30150.1 - 1.9e-13 50.2 0.0 1.1e-06 28.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CAR30150.1 - 2e-11 43.0 0.0 2.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat eIF-5_eIF-2B PF01873.17 CAR30151.1 - 1e-36 125.4 0.2 2.1e-36 124.3 0.2 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.15 CAR30151.1 - 0.011 15.5 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.12 CAR30151.1 - 0.014 14.9 0.1 0.029 13.9 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding PRP9_N PF16958.5 CAR30151.1 - 0.018 15.0 0.7 4.7 7.2 0.7 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor PRP9 N-terminus XPC-binding PF09280.11 CAR30151.1 - 0.12 12.1 0.2 15 5.4 0.0 2.3 2 0 0 2 2 2 0 XPC-binding domain DUF2752 PF10825.8 CAR30151.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Pkinase PF00069.25 CAR30153.1 - 6.3e-38 130.7 0.0 6.7e-26 91.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30153.1 - 6.8e-21 74.7 0.0 4e-15 55.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR30153.1 - 0.054 12.8 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Kinase-like TIP49 PF06068.13 CAR30154.1 - 4.7e-158 526.0 2.0 5.9e-158 525.6 2.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CAR30154.1 - 1.1e-23 83.2 1.0 3.4e-23 81.6 0.8 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CAR30154.1 - 2.7e-08 34.3 0.5 5.4e-05 23.6 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAR30154.1 - 7.2e-08 32.3 0.5 0.00055 19.7 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 CAR30154.1 - 6.1e-06 25.8 0.2 1.4e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CAR30154.1 - 7.8e-06 26.4 0.4 2.4e-05 24.8 0.4 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR30154.1 - 0.00073 19.8 0.1 0.23 11.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAR30154.1 - 0.003 17.0 1.0 0.055 12.8 0.3 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CAR30154.1 - 0.0033 17.8 0.4 0.034 14.5 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAR30154.1 - 0.0047 16.9 0.2 0.81 9.7 0.0 2.8 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CAR30154.1 - 0.0053 17.0 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CAR30154.1 - 0.0073 15.9 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CAR30154.1 - 0.031 14.0 0.0 7.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ATP-synt_C PF00137.21 CAR30155.1 - 6.3e-32 109.7 32.2 3.5e-18 65.7 9.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Mis14 PF08641.12 CAR30156.1 - 2.5e-34 118.4 6.9 2.5e-34 118.4 6.9 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like Syntaxin PF00804.25 CAR30157.1 - 7.5e-21 74.7 15.2 7.5e-21 74.7 15.2 2.4 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 CAR30157.1 - 9e-15 54.4 4.2 9e-15 54.4 4.2 2.0 2 0 0 2 2 2 1 SNARE domain Synaptobrevin PF00957.21 CAR30157.1 - 0.00016 21.4 2.5 0.00016 21.4 2.5 2.4 2 0 0 2 2 2 1 Synaptobrevin Thr_dehydrat_C PF00585.18 CAR30157.1 - 0.004 16.9 1.8 0.033 14.0 0.0 3.0 3 1 0 3 3 3 1 C-terminal regulatory domain of Threonine dehydratase SKA1 PF07160.12 CAR30157.1 - 0.0066 16.3 3.3 0.0066 16.3 3.3 2.1 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 T2SSF PF00482.23 CAR30157.1 - 0.0086 16.0 0.5 0.031 14.2 0.5 2.0 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F DUF745 PF05335.13 CAR30157.1 - 0.01 15.6 7.6 0.01 15.6 7.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF745) DUF2207 PF09972.9 CAR30157.1 - 0.012 14.4 1.8 0.013 14.3 0.3 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF948 PF06103.11 CAR30157.1 - 0.017 15.4 3.8 0.017 15.4 3.8 3.1 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) SLATT_5 PF18160.1 CAR30157.1 - 0.028 13.7 1.4 0.031 13.6 0.0 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2277 PF10041.9 CAR30157.1 - 0.18 12.2 3.9 0.89 9.9 0.8 2.9 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) Herpes_US9 PF06072.11 CAR30157.1 - 0.2 11.6 0.8 0.4 10.6 0.8 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF2116 PF09889.9 CAR30157.1 - 0.3 11.1 1.4 0.95 9.5 1.4 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PBP1_TM PF14812.6 CAR30157.1 - 0.35 11.3 0.2 0.35 11.3 0.2 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Allexi_40kDa PF05549.11 CAR30157.1 - 0.84 9.1 8.5 1.4 8.4 1.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein SlyX PF04102.12 CAR30157.1 - 4.4 8.0 13.5 0.33 11.6 4.6 2.9 2 1 0 2 2 2 0 SlyX DUF1664 PF07889.12 CAR30157.1 - 6.4 6.8 9.3 1.5 8.9 3.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CAR30157.1 - 6.7 4.5 14.5 15 3.3 14.5 1.5 1 1 0 1 1 1 0 Prominin VSG_B PF13206.6 CAR30157.1 - 9.2 5.4 13.0 14 4.8 12.5 1.5 1 1 0 1 1 1 0 Trypanosomal VSG domain Fas_alpha_ACP PF18325.1 CAR30158.1 - 1e-74 250.3 0.1 2.3e-74 249.1 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 CAR30158.1 - 3.8e-69 232.4 1.1 1e-68 231.0 0.4 2.1 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 CAR30158.1 - 1.2e-21 77.4 0.0 3e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 CAR30158.1 - 5.6e-17 61.9 0.0 1.4e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 CAR30158.1 - 1.1e-10 41.6 0.0 2.8e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CAR30158.1 - 0.0007 19.5 0.1 0.0039 17.1 0.0 2.2 2 0 0 2 2 2 1 KR domain DEC-1_N PF04625.13 CAR30158.1 - 2.5 7.0 12.0 6.3 5.7 12.0 1.7 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF4452 PF14618.6 CAR30159.1 - 0.026 14.4 0.6 0.032 14.1 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4452) mRNA_triPase PF02940.15 CAR30160.1 - 7.4e-65 218.7 1.4 7.4e-65 218.7 1.4 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.26 CAR30161.1 - 5.9e-24 84.8 0.0 7.4e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CAR30161.1 - 0.0002 21.3 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CAR30161.1 - 0.032 14.7 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.27 CAR30163.1 - 9.2e-48 162.2 0.0 9.4e-26 91.0 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAR30163.1 - 3.3e-15 56.7 0.9 0.00025 20.9 0.0 5.2 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR30163.1 - 2.3e-12 46.8 0.0 0.0024 17.4 0.0 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 CAR30163.1 - 1.2e-09 37.9 0.8 2.7e-09 36.8 0.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 CAR30163.1 - 6.1e-09 36.7 0.1 0.00059 20.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CAR30163.1 - 6e-07 29.1 0.4 0.013 15.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR30163.1 - 7.9e-07 29.1 0.1 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR30163.1 - 9.7e-07 28.9 0.0 0.01 15.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CAR30163.1 - 1.6e-05 25.5 0.6 0.19 12.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CAR30163.1 - 2.8e-05 24.4 0.2 0.35 11.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain DUF87 PF01935.17 CAR30163.1 - 6.8e-05 23.1 1.6 0.04 14.0 0.0 3.6 4 1 0 4 4 3 1 Helicase HerA, central domain RNA_helicase PF00910.22 CAR30163.1 - 7.3e-05 23.1 0.2 2 8.8 0.0 3.6 3 0 0 3 3 3 2 RNA helicase MeaB PF03308.16 CAR30163.1 - 0.00052 19.1 0.4 0.84 8.6 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CAR30163.1 - 0.00062 20.2 0.6 0.17 12.2 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 CAR30163.1 - 0.0014 18.6 0.1 1.2 9.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 CAR30163.1 - 0.0016 18.2 0.2 1.4 8.6 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_15 PF13175.6 CAR30163.1 - 0.0017 18.2 0.7 1 9.0 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_28 PF13521.6 CAR30163.1 - 0.002 18.4 0.0 0.4 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CAR30163.1 - 0.0025 18.2 0.0 8.6 6.8 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 CAR30163.1 - 0.0054 16.3 0.0 3.4 7.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR30163.1 - 0.0056 16.9 0.0 5 7.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 CAR30163.1 - 0.0096 14.6 0.0 2 7.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CAR30163.1 - 0.016 15.2 0.0 3.8 7.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CAR30163.1 - 0.017 14.8 0.1 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CAR30163.1 - 0.022 14.6 0.0 4.8 7.1 0.1 3.1 3 0 0 3 3 3 0 NTPase Thymidylate_kin PF02223.17 CAR30163.1 - 0.03 14.0 0.2 0.26 11.0 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase DUF815 PF05673.13 CAR30163.1 - 0.033 13.3 0.2 3.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CLP1_P PF16575.5 CAR30163.1 - 0.034 13.9 0.2 6.6 6.5 0.0 3.2 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Roc PF08477.13 CAR30163.1 - 0.037 14.3 0.0 11 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CAR30163.1 - 0.037 14.0 0.3 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CAR30163.1 - 0.04 13.1 0.2 1.7 7.8 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 CAR30163.1 - 0.053 13.5 0.2 0.44 10.4 0.0 2.5 3 0 0 3 3 2 0 Rad17 P-loop domain Dynamin_N PF00350.23 CAR30163.1 - 0.076 13.1 0.0 2.1 8.4 0.0 3.0 3 0 0 3 3 2 0 Dynamin family DUF3584 PF12128.8 CAR30163.1 - 0.083 10.4 1.0 4.5 4.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) cobW PF02492.19 CAR30163.1 - 0.1 12.1 0.1 29 4.2 0.0 3.2 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain MoCF_biosynth PF00994.24 CAR30164.1 - 9.1e-31 106.5 0.0 1.6e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain Polysacc_synt_4 PF04669.13 CAR30165.1 - 7.1e-18 64.8 2.3 3.6e-16 59.3 2.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis NitrOD1 PF18549.1 CAR30165.1 - 0.084 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 Cation_efflux PF01545.21 CAR30166.1 - 2e-43 148.4 12.0 3.2e-43 147.8 12.0 1.3 1 0 0 1 1 1 1 Cation efflux family JmjC PF02373.22 CAR30167.1 - 2.8e-17 63.2 0.0 9.2e-10 39.0 0.0 2.9 2 0 0 2 2 2 2 JmjC domain, hydroxylase ARID PF01388.21 CAR30167.1 - 2.6e-16 60.0 0.0 1.2e-15 57.9 0.0 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PLU-1 PF08429.11 CAR30167.1 - 1.2e-11 44.4 1.6 3.4e-11 42.9 0.6 2.1 2 0 0 2 2 2 1 PLU-1-like protein PHD PF00628.29 CAR30167.1 - 2.2e-06 27.4 9.5 4.9e-06 26.3 9.5 1.6 1 0 0 1 1 1 1 PHD-finger HisKA PF00512.25 CAR30167.1 - 0.043 13.9 0.4 0.2 11.7 0.1 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain JmjN PF02375.17 CAR30167.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 jmjN domain C1_1 PF00130.22 CAR30167.1 - 0.15 12.0 2.4 0.46 10.4 2.4 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CAR30167.1 - 0.21 11.7 7.5 0.6 10.2 7.5 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.6 CAR30167.1 - 1.2 9.6 8.3 2.9 8.3 8.3 1.7 1 0 0 1 1 1 0 Ring finger domain GCR1_C PF12550.8 CAR30171.1 - 1.3e-20 73.5 0.3 3e-20 72.3 0.3 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes UPF0061 PF02696.14 CAR30172.1 - 7.8e-149 496.4 0.0 9.2e-149 496.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family GIT1_C PF12205.8 CAR30172.1 - 0.14 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Lon_C PF05362.13 CAR30173.1 - 6.5e-46 156.5 0.0 1.2e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CAR30173.1 - 2.1e-19 70.3 0.0 4.6e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR30173.1 - 2.4e-07 30.9 0.0 7.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 CAR30173.1 - 9.4e-07 28.9 0.1 2.2e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 CAR30173.1 - 2.5e-06 27.3 0.0 4.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 CAR30173.1 - 0.00016 21.9 0.0 0.00052 20.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CAR30173.1 - 0.0005 20.5 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR30173.1 - 0.0014 18.4 0.1 0.0068 16.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CAR30173.1 - 0.0067 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR30173.1 - 0.012 15.9 0.0 0.19 12.0 0.0 2.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CAR30173.1 - 0.012 16.1 0.1 0.046 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_PrkA PF08298.11 CAR30173.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Mg_chelatase PF01078.21 CAR30173.1 - 0.014 14.8 0.1 0.035 13.5 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PLU-1 PF08429.11 CAR30173.1 - 0.047 12.9 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 PLU-1-like protein NTPase_1 PF03266.15 CAR30173.1 - 0.057 13.3 0.1 0.23 11.3 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_14 PF13173.6 CAR30173.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAR30173.1 - 0.074 13.6 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 CAR30173.1 - 0.088 12.5 0.1 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAR30173.1 - 0.094 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ClpB_D2-small PF10431.9 CAR30173.1 - 0.094 12.8 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein SMC_N PF02463.19 CAR30173.1 - 0.095 12.1 0.2 7.1 6.0 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain ResIII PF04851.15 CAR30173.1 - 0.1 12.6 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CAR30173.1 - 0.11 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CAR30173.1 - 0.15 12.4 0.1 0.39 11.1 0.1 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CAR30173.1 - 0.16 11.7 0.1 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 CAR30173.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CAR30173.1 - 0.18 11.5 0.0 1 9.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain TRP PF06011.12 CAR30174.1 - 1.1e-156 521.8 32.1 1.5e-156 521.4 32.1 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CAR30174.1 - 1.5e-40 138.8 0.3 2.7e-40 137.9 0.3 1.4 1 0 0 1 1 1 1 ML-like domain DUF4459 PF14673.6 CAR30174.1 - 0.024 14.6 0.0 0.061 13.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Coatomer_WDAD PF04053.14 CAR30176.1 - 1.2e-162 542.0 0.0 2e-162 541.3 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CAR30176.1 - 2.7e-33 113.4 4.4 1.2e-05 25.9 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 CAR30176.1 - 1.7e-05 23.7 2.8 0.052 12.2 0.1 4.0 1 1 3 4 4 4 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CAR30176.1 - 0.00062 19.8 0.0 0.26 11.3 0.0 3.7 2 1 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 CAR30176.1 - 0.023 14.9 0.1 0.48 10.7 0.0 2.9 2 1 1 3 3 3 0 C terminal of Calcineurin-like phosphoesterase FtsJ PF01728.19 CAR30177.1 - 2.7e-55 187.2 0.0 3.4e-55 186.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CAR30177.1 - 0.00015 21.5 0.0 0.39 10.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CAR30177.1 - 0.00016 21.5 0.0 0.001 18.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_L1 PF00687.21 CAR30178.1 - 2.1e-43 148.4 1.8 2.7e-43 148.1 0.9 1.5 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family MetOD2 PF18548.1 CAR30178.1 - 0.12 12.5 0.2 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 Metanogen output domain 2 Cyclin PF08613.11 CAR30179.1 - 6.1e-18 65.7 0.1 1.3e-17 64.7 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CAR30179.1 - 0.0004 20.1 0.7 0.00083 19.1 0.7 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arf PF00025.21 CAR30180.1 - 1.1e-66 223.6 0.0 1.3e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAR30180.1 - 1.6e-09 37.4 0.3 2.7e-06 26.8 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CAR30180.1 - 4.9e-08 32.6 0.0 6.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAR30180.1 - 2e-07 30.7 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR30180.1 - 1.4e-06 28.5 0.0 4.1e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CAR30180.1 - 5.9e-06 26.3 0.0 7.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAR30180.1 - 8.6e-05 22.0 0.0 9.6e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR30180.1 - 0.0034 16.9 0.1 0.049 13.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CAR30180.1 - 0.071 12.9 0.0 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RIBIOP_C PF04950.12 CAR30181.1 - 5.4e-87 291.9 0.1 5.4e-87 291.9 0.1 2.5 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CAR30181.1 - 1.5e-28 98.7 0.0 7.3e-28 96.5 0.0 2.3 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CAR30181.1 - 3.4e-06 26.7 3.2 0.0002 20.9 0.0 2.8 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CAR30181.1 - 4.8e-06 27.0 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CAR30181.1 - 7.9e-06 26.1 0.0 2.7e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAR30181.1 - 2.6e-05 24.7 0.0 6.7e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR30181.1 - 6.7e-05 23.2 0.1 0.00026 21.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 CAR30181.1 - 0.0014 18.0 0.1 0.035 13.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 CAR30181.1 - 0.006 16.9 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAR30181.1 - 0.0062 16.8 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CAR30181.1 - 0.007 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 CAR30181.1 - 0.0071 16.9 0.0 0.0071 16.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 CAR30181.1 - 0.0077 16.3 0.2 0.033 14.3 0.1 2.2 2 1 0 2 2 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 CAR30181.1 - 0.0089 15.8 1.1 0.012 15.3 0.1 1.7 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CAR30181.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 CAR30181.1 - 0.012 14.8 0.4 0.027 13.7 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 CAR30181.1 - 0.012 15.1 0.1 0.035 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CAR30181.1 - 0.014 15.4 0.1 0.038 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CAR30181.1 - 0.014 15.2 0.1 0.014 15.2 0.1 4.1 3 1 0 3 3 2 0 AAA domain cobW PF02492.19 CAR30181.1 - 0.022 14.3 0.3 0.051 13.2 0.3 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CAR30181.1 - 0.033 14.1 0.7 0.071 13.0 0.7 1.5 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 CAR30181.1 - 0.034 14.7 1.8 0.053 14.0 0.0 2.2 2 0 0 2 2 1 0 ABC transporter MobB PF03205.14 CAR30181.1 - 0.053 13.4 0.6 0.15 11.9 0.2 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 CAR30181.1 - 0.055 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CAR30181.1 - 0.15 11.8 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RuvB_N PF05496.12 CAR30181.1 - 0.17 11.6 0.0 0.79 9.4 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain WAC_Acf1_DNA_bd PF10537.9 CAR30182.1 - 9.8e-35 119.1 2.0 9.8e-35 119.1 2.0 3.0 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CAR30182.1 - 7.1e-07 29.6 0.0 2.2e-05 24.8 0.0 3.3 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CAR30182.1 - 2.4e-06 27.8 0.1 1.1e-05 25.6 0.1 2.2 1 0 0 1 1 1 1 DDT domain PEP-utilisers_N PF05524.13 CAR30182.1 - 0.26 11.5 4.0 0.79 9.9 4.0 1.8 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF1043 PF06295.12 CAR30182.1 - 1.3 9.0 10.4 0.57 10.2 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Ubiq_cyt_C_chap PF03981.12 CAR30183.1 - 3.7e-42 143.8 0.4 5.7e-42 143.1 0.4 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.15 CAR30184.1 - 2.6e-84 282.5 1.6 3.8e-84 281.9 1.6 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CAR30184.1 - 2e-59 200.0 0.0 2.9e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine monophosphate synthase LRR_9 PF14580.6 CAR30185.1 - 2.5e-18 66.2 0.0 4.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAR30185.1 - 7e-09 35.8 1.6 0.0012 19.3 0.1 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR30185.1 - 0.00079 19.1 6.8 0.0084 15.9 2.8 3.1 1 1 2 3 3 3 2 Leucine rich repeat FliG_C PF01706.16 CAR30185.1 - 0.028 14.6 1.2 1.4 9.2 0.3 2.8 3 0 0 3 3 3 0 FliG C-terminal domain LRR_1 PF00560.33 CAR30185.1 - 0.28 11.9 6.7 25 5.9 0.1 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat BAH PF01426.18 CAR30186.1 - 4.1e-17 62.2 0.4 1e-16 60.9 0.4 1.7 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 CAR30186.1 - 3.8e-08 33.1 31.1 1.3e-06 28.2 10.5 6.5 7 1 0 7 7 7 3 PHD-finger Myb_DNA-binding PF00249.31 CAR30186.1 - 0.00041 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain PHD_2 PF13831.6 CAR30186.1 - 0.0044 16.5 2.1 0.0044 16.5 2.1 5.7 5 1 0 5 5 5 2 PHD-finger COMPASS-Shg1 PF05205.12 CAR30186.1 - 0.006 17.3 0.6 0.006 17.3 0.6 2.6 2 1 1 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 EELM2 PF15863.5 CAR30186.1 - 0.0089 16.2 0.0 0.0089 16.2 0.0 4.0 4 1 0 4 4 4 1 Extended EGL-27 and MTA1 homology domain DUF2400 PF09674.10 CAR30186.1 - 0.12 12.4 4.7 0.13 12.2 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) mRNA_cap_enzyme PF01331.19 CAR30187.1 - 5.8e-63 212.2 0.0 1e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CAR30187.1 - 2.2e-30 105.5 0.1 3.9e-30 104.7 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CAR30187.1 - 1.4e-05 24.8 0.0 0.0053 16.4 0.0 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF4065 PF13274.6 CAR30187.1 - 0.12 13.2 0.5 1 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DAP3 PF10236.9 CAR30188.1 - 3.5e-87 292.5 0.2 6.4e-87 291.6 0.3 1.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CAR30188.1 - 7.6e-08 32.9 0.0 1.9e-07 31.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR30188.1 - 3e-05 24.3 0.0 0.00019 21.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CAR30188.1 - 0.00058 19.6 0.1 0.18 11.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR30188.1 - 0.0013 18.6 0.0 0.006 16.5 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CAR30188.1 - 0.0018 18.8 0.1 1 9.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.12 CAR30188.1 - 0.014 15.4 0.0 0.18 11.7 0.0 2.8 3 0 0 3 3 3 0 NACHT domain DUF2183 PF09949.9 CAR30188.1 - 0.019 15.3 0.1 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Sigma54_activat PF00158.26 CAR30188.1 - 0.019 14.7 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 CAR30188.1 - 0.038 13.2 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain DUF815 PF05673.13 CAR30188.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 CAR30188.1 - 0.054 13.4 0.1 0.37 10.7 0.0 2.4 3 1 0 3 3 3 0 NTPase AAA PF00004.29 CAR30188.1 - 0.055 13.9 0.0 0.84 10.1 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAR30188.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAR30188.1 - 0.084 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF3849 PF12960.7 CAR30188.1 - 0.17 11.9 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) PseudoU_synth_1 PF01416.20 CAR30189.1 - 1.3e-14 54.6 0.0 1.1e-12 48.3 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase UPF0113_N PF17833.1 CAR30190.1 - 8e-30 103.2 0.1 1.2e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CAR30190.1 - 6e-25 87.3 0.0 1.4e-24 86.1 0.0 1.6 2 0 0 2 2 2 1 UPF0113 PUA domain SRP72 PF08492.12 CAR30191.1 - 9.7e-12 45.1 4.4 9.7e-12 45.1 4.4 2.6 3 0 0 3 3 1 1 SRP72 RNA-binding domain TPR_14 PF13428.6 CAR30191.1 - 9.1e-06 26.1 0.4 4.1 8.5 0.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CAR30191.1 - 1.9e-05 24.6 8.2 0.00014 21.9 2.1 3.7 3 1 0 3 3 3 1 Putative TPR-like repeat TPR_19 PF14559.6 CAR30191.1 - 2.7e-05 24.6 5.8 0.1 13.1 2.7 4.2 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR30191.1 - 2.9e-05 23.9 6.5 0.51 10.6 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR30191.1 - 0.00011 21.7 0.8 0.0025 17.2 0.1 2.9 3 1 1 4 4 4 1 MalT-like TPR region TPR_12 PF13424.6 CAR30191.1 - 0.0003 21.0 6.2 0.1 12.9 0.6 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR30191.1 - 0.0018 18.3 11.5 1.4 9.3 0.3 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat PPR PF01535.20 CAR30191.1 - 0.012 15.8 1.5 2.4 8.6 0.0 4.7 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.6 CAR30191.1 - 0.03 14.9 0.6 54 4.7 0.1 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR30191.1 - 0.043 13.6 2.2 1.7 8.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR30191.1 - 0.1 12.7 0.3 0.88 9.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DEAD PF00270.29 CAR30192.1 - 1.2e-30 106.6 0.1 1.1e-29 103.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30192.1 - 1.2e-18 67.4 1.1 9.9e-18 64.5 0.5 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30192.1 - 4.9e-08 33.2 0.0 1e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR30192.1 - 0.045 14.0 0.1 0.53 10.6 0.1 2.6 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 CAR30193.1 - 8.2e-75 251.6 0.3 9.9e-75 251.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30193.1 - 9.2e-48 162.8 0.0 1.2e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR30193.1 - 2e-06 27.4 0.0 7.2e-06 25.5 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAR30193.1 - 0.00045 19.6 0.2 0.0021 17.5 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CAR30193.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 CAR30193.1 - 0.037 13.6 0.8 0.58 9.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CAR30193.1 - 0.055 12.2 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase SET PF00856.28 CAR30194.1 - 5e-10 40.0 0.1 1.8e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 SET domain Wyosine_form PF08608.12 CAR30195.1 - 2.9e-23 82.0 0.0 7.7e-23 80.6 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CAR30195.1 - 1.6e-22 80.7 0.0 5.9e-22 78.8 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CAR30195.1 - 8.2e-12 45.5 0.0 2.2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin DUF1992 PF09350.10 CAR30196.1 - 2.8e-16 59.4 0.0 1.2e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) Glycos_transf_1 PF00534.20 CAR30197.1 - 7.6e-35 120.0 0.0 1.9e-33 115.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR30197.1 - 1.9e-16 60.5 0.0 3.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CAR30197.1 - 2.4e-13 50.7 0.0 8.4e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CAR30197.1 - 0.0023 18.4 0.0 0.0044 17.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 CAR30197.1 - 0.01 15.9 0.5 3.1 7.8 0.2 2.7 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus Methyltransf_8 PF05148.15 CAR30197.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase SCA7 PF08313.12 CAR30198.1 - 1.4e-29 101.8 0.6 6.3e-29 99.7 0.4 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 CAR30198.1 - 3.5e-19 68.1 0.1 7.7e-19 67.0 0.1 1.6 1 0 0 1 1 1 1 Zinc finger domain FapA PF03961.13 CAR30198.1 - 0.066 11.8 10.2 0.1 11.2 8.7 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 CAR30198.1 - 0.52 8.2 15.5 0.91 7.4 15.5 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 CAR30198.1 - 0.88 8.4 7.2 1.2 8.0 7.2 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein PA26 PF04636.13 CAR30198.1 - 1.4 7.8 14.8 3.1 6.6 14.8 1.6 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1682 PF07946.14 CAR30198.1 - 3 7.0 22.0 6.3 5.9 22.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Membralin PF09746.9 CAR30198.1 - 3.1 6.8 12.4 6.5 5.7 12.4 1.6 1 0 0 1 1 1 0 Tumour-associated protein SID-1_RNA_chan PF13965.6 CAR30198.1 - 3.2 6.1 5.3 5.2 5.4 5.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Cellulose_synt PF03552.14 CAR30198.1 - 3.7 5.9 6.2 5.5 5.4 6.2 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF2052 PF09747.9 CAR30198.1 - 8.5 6.4 27.2 5.6 7.0 21.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GDPD PF03009.17 CAR30199.1 - 4.2e-32 111.9 0.2 1.6e-31 110.0 0.2 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF5331 PF17265.2 CAR30199.1 - 0.13 12.0 1.0 0.25 11.1 1.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5331) NUDIX PF00293.28 CAR30200.1 - 7.7e-17 61.6 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CAR30200.1 - 4.7e-07 29.3 0.3 8.3e-07 28.6 0.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 CAR30200.1 - 0.0043 17.7 0.0 0.0097 16.6 0.0 1.6 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain Pkinase PF00069.25 CAR30201.1 - 1.1e-23 84.0 0.0 1.8e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30201.1 - 2e-13 50.2 0.0 3.2e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR30201.1 - 1.9e-08 33.5 0.1 1.9e-08 33.5 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CAR30201.1 - 0.055 12.4 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 CAR30201.1 - 0.073 13.0 0.1 0.073 13.0 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family P16-Arc PF04699.14 CAR30201.1 - 1.5 9.3 5.2 3.6 8.1 5.2 1.6 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Pkinase PF00069.25 CAR30202.1 - 4.7e-72 242.5 0.0 5.5e-72 242.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30202.1 - 4e-39 134.5 0.0 5.2e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR30202.1 - 1.5e-06 27.7 0.0 3.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAR30202.1 - 0.042 12.8 0.1 0.06 12.3 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAR30202.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L12 PF00542.19 CAR30203.1 - 4.3e-22 78.3 8.4 4.3e-22 78.3 8.4 2.4 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CAR30203.1 - 9.9e-16 57.2 9.0 1.2e-15 57.0 3.5 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 CAR30203.1 - 0.019 15.5 10.8 0.019 15.5 10.8 2.5 2 2 0 2 2 2 0 60s Acidic ribosomal protein RNA_POL_M_15KD PF02150.16 CAR30204.1 - 9.3e-16 57.4 3.3 9.3e-16 57.4 3.3 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CAR30204.1 - 6.7e-14 51.5 1.3 6.7e-14 51.5 1.3 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF2387 PF09526.10 CAR30204.1 - 0.081 13.1 4.6 1.5 9.0 0.3 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1 PF03811.13 CAR30204.1 - 0.24 11.2 0.4 0.24 11.2 0.4 3.6 4 0 0 4 4 4 0 InsA N-terminal domain DZR PF12773.7 CAR30204.1 - 0.25 11.4 7.5 1.3 9.1 0.7 2.5 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 CAR30204.1 - 0.29 10.9 6.7 1.4 8.7 0.5 2.5 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 PF12760.7 CAR30204.1 - 0.41 10.7 10.9 1.4 9.0 2.7 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-UBP PF02148.19 CAR30204.1 - 0.41 11.0 3.9 1.6 9.1 0.4 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.10 CAR30204.1 - 2.8 8.1 11.6 3.7 7.8 0.1 3.7 3 1 1 4 4 4 0 Zinc ribbon domain AFT PF08731.11 CAR30205.1 - 5.3e-47 158.8 0.9 5.3e-47 158.8 0.9 1.7 2 0 0 2 2 2 1 Transcription factor AFT DBD_Tnp_Mut PF03108.15 CAR30205.1 - 0.041 13.9 0.5 12 5.9 0.2 2.4 2 0 0 2 2 2 0 MuDR family transposase HSF_DNA-bind PF00447.17 CAR30207.1 - 1.3e-31 109.1 2.9 2.6e-31 108.1 2.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding MPS2 PF17060.5 CAR30208.1 - 3.5e-166 553.1 0.2 3.9e-166 552.9 0.2 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 FAM76 PF16046.5 CAR30208.1 - 0.002 17.6 7.3 0.2 11.0 0.8 2.1 1 1 1 2 2 2 2 FAM76 protein LCD1 PF09798.9 CAR30208.1 - 0.0031 16.1 2.3 0.0042 15.7 2.3 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein Tropomyosin_1 PF12718.7 CAR30208.1 - 0.014 15.5 7.8 0.015 15.4 6.8 1.6 1 1 0 1 1 1 0 Tropomyosin like SlyX PF04102.12 CAR30208.1 - 0.035 14.7 9.0 1.2 9.8 0.5 3.4 2 1 1 3 3 3 0 SlyX ATG16 PF08614.11 CAR30208.1 - 0.088 13.0 12.1 0.1 12.8 1.2 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) GPHH PF16905.5 CAR30208.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Lebercilin PF15619.6 CAR30208.1 - 0.19 11.3 13.0 0.061 13.0 1.2 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease KASH_CCD PF14662.6 CAR30208.1 - 0.91 9.3 10.8 0.33 10.8 5.4 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Troponin PF00992.20 CAR30208.1 - 1.2 9.5 10.1 3.3 8.0 0.9 2.6 2 1 1 3 3 3 0 Troponin DUF724 PF05266.14 CAR30208.1 - 1.5 8.6 9.7 1.2 8.9 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF16 PF01519.16 CAR30208.1 - 2.8 8.5 9.7 9.5 6.8 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 UPF0242 PF06785.11 CAR30208.1 - 4.7 7.3 13.3 29 4.7 13.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TSC22 PF01166.18 CAR30208.1 - 6.1 7.2 6.2 10 6.5 0.8 3.3 3 1 1 4 4 3 0 TSC-22/dip/bun family DUF1771 PF08590.10 CAR30209.1 - 3.7e-19 68.8 8.5 3.7e-19 68.8 8.5 2.3 2 1 1 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.21 CAR30209.1 - 4.9e-11 42.8 0.6 1.2e-10 41.6 0.1 1.9 2 0 0 2 2 2 1 Smr domain CYSTM PF12734.7 CAR30209.1 - 0.0007 19.9 8.1 0.0007 19.9 8.1 3.0 2 1 1 3 3 3 1 Cysteine-rich TM module stress tolerance Neur_chan_memb PF02932.16 CAR30209.1 - 2.1 8.3 9.0 1.1 9.2 1.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MMU163 PF17119.5 CAR30209.1 - 2.2 7.4 8.6 0.087 12.0 2.1 1.8 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Pex14_N PF04695.13 CAR30209.1 - 2.6 8.7 24.0 0.085 13.5 14.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4407 PF14362.6 CAR30209.1 - 3.8 6.8 15.7 0.92 8.8 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Orf78 PF06024.12 CAR30209.1 - 6.6 7.1 8.0 0.39 11.0 0.6 2.4 2 1 0 2 2 2 0 Orf78 (ac78) Myb_DNA-bind_4 PF13837.6 CAR30210.1 - 0.0015 18.9 0.0 0.017 15.5 0.0 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Fez1 PF06818.15 CAR30210.1 - 0.034 14.6 0.1 0.051 14.0 0.1 1.2 1 0 0 1 1 1 0 Fez1 Myb_DNA-binding PF00249.31 CAR30210.1 - 0.046 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain SlyX PF04102.12 CAR30210.1 - 0.08 13.6 1.0 0.18 12.4 1.0 1.6 1 0 0 1 1 1 0 SlyX Filament PF00038.21 CAR30210.1 - 0.085 12.4 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein Myb_DNA-bind_6 PF13921.6 CAR30210.1 - 0.13 12.5 0.0 0.5 10.7 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Ribosomal_L30_N PF08079.12 CAR30211.1 - 4.4e-22 78.1 15.7 7.7e-22 77.3 15.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CAR30211.1 - 5.6e-17 61.4 2.4 1.5e-16 60.0 2.4 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e AA_permease_2 PF13520.6 CAR30212.1 - 3.4e-51 174.4 45.9 4.1e-51 174.2 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR30212.1 - 7e-21 74.4 39.6 9.4e-21 73.9 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.29 CAR30213.1 - 1.9e-52 177.6 0.0 1.1e-51 175.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30213.1 - 3.2e-37 127.3 0.1 3.3e-31 107.9 0.1 3.2 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30213.1 - 6.3e-09 36.1 4.3 2.6e-08 34.1 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR30213.1 - 6.4e-05 22.3 0.0 6.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CAR30213.1 - 0.0013 18.2 0.0 0.0013 18.2 0.0 2.8 2 1 0 2 2 1 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CAR30213.1 - 0.011 14.5 0.1 0.011 14.5 0.1 3.5 3 1 1 4 4 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CAR30213.1 - 0.11 12.8 0.4 0.6 10.4 0.4 2.2 1 1 0 1 1 1 0 AAA domain CAF-1_p150 PF11600.8 CAR30213.1 - 0.17 11.5 28.5 0.34 10.6 28.5 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rhodanese PF00581.20 CAR30213.1 - 0.19 12.3 3.3 0.2 12.2 0.0 2.6 2 0 0 2 2 2 0 Rhodanese-like domain Zip PF02535.22 CAR30213.1 - 0.34 10.1 5.1 0.46 9.6 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4718 PF15842.5 CAR30213.1 - 1.2 8.9 8.3 2.2 8.0 8.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Vfa1 PF08432.10 CAR30213.1 - 6.1 7.1 26.4 14 5.9 26.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FA_desaturase PF00487.24 CAR30214.1 - 8.3e-30 104.5 24.3 1.2e-29 103.9 24.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAR30214.1 - 4.1e-12 46.1 0.0 9.5e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TLD PF07534.16 CAR30215.1 - 4e-30 104.8 0.0 1.5e-29 103.0 0.0 1.8 1 1 0 1 1 1 1 TLD KxDL PF10241.9 CAR30216.1 - 4.9e-24 84.4 1.6 6.6e-24 84.0 1.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein HAUS6_N PF14661.6 CAR30216.1 - 0.02 14.5 0.5 0.028 14.0 0.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF790 PF05626.11 CAR30216.1 - 0.02 13.6 0.6 0.027 13.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Sec34 PF04136.15 CAR30216.1 - 0.071 13.0 1.5 0.2 11.5 1.6 1.7 1 1 0 1 1 1 0 Sec34-like family HSCB_C PF07743.13 CAR30216.1 - 0.098 13.2 3.6 8.1 7.0 0.1 3.1 1 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain YqaH PF17448.2 CAR30216.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized YqaH-like H-kinase_dim PF02895.14 CAR30216.1 - 1.8 9.0 4.3 22 5.6 4.2 2.2 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Adaptin_N PF01602.20 CAR30217.1 - 8.4e-117 390.9 12.0 1.2e-116 390.4 12.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR30217.1 - 6.6e-10 39.3 3.6 7e-08 32.7 0.1 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAR30217.1 - 7.3e-07 28.9 0.1 22 5.7 0.0 7.3 8 0 0 8 8 8 2 HEAT repeat Cnd3 PF12719.7 CAR30217.1 - 2.3e-05 23.7 1.9 0.018 14.2 0.0 3.6 2 1 1 3 3 3 3 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CAR30217.1 - 0.0018 18.6 0.0 10 6.6 0.0 4.0 3 3 1 4 4 4 2 HEAT repeats Rad9 PF04139.13 CAR30218.1 - 4e-13 49.4 0.1 2.5e-05 23.9 0.1 2.2 2 0 0 2 2 2 2 Rad9 NUFIP1 PF10453.9 CAR30219.1 - 1.5e-17 63.1 6.5 4.6e-17 61.6 6.5 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF2031 PF09592.10 CAR30219.1 - 7.9 5.9 11.0 12 5.4 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) FHA PF00498.26 CAR30220.1 - 0.00062 20.1 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain DALR_2 PF09190.11 CAR30220.1 - 0.089 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 DALR domain MINDY_DUB PF04424.13 CAR30221.1 - 5.9e-31 106.9 0.0 1.1e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase RRM_1 PF00076.22 CAR30222.1 - 5.8e-09 35.6 0.1 1.6e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR30222.1 - 0.00047 19.8 0.0 0.0025 17.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CAR30223.1 - 2.5e-22 79.5 0.0 4.5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30223.1 - 1e-11 44.6 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MBOAT PF03062.19 CAR30224.1 - 2.4e-72 244.2 22.2 3.6e-72 243.6 22.2 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.17 CAR30225.1 - 1.6e-25 89.6 0.0 2.5e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAD PF05557.13 CAR30226.1 - 3.3e-26 91.9 76.8 4.3e-26 91.5 76.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein L_protein_N PF15518.6 CAR30226.1 - 0.11 12.3 0.2 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 L protein N-terminus BRI3BP PF14965.6 CAR30226.1 - 0.15 11.5 0.9 2.5 7.6 0.1 2.9 3 0 0 3 3 3 0 Negative regulator of p53/TP53 DUF4250 PF14056.6 CAR30226.1 - 7.4 6.6 14.8 30 4.7 0.5 5.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) Tweety PF04906.13 CAR30226.1 - 8.7 4.9 16.9 2.2 6.8 1.9 3.5 2 1 0 3 3 3 0 Tweety UQ_con PF00179.26 CAR30227.1 - 5.3e-17 61.8 0.0 5.6e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR30227.1 - 0.0062 16.8 0.0 0.007 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain MOSC PF03473.17 CAR30227.1 - 0.088 12.8 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 MOSC domain NAD_kinase PF01513.21 CAR30228.1 - 2.2e-53 181.3 0.0 3e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CAR30228.1 - 0.0046 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Viral_DNA_bp PF00747.17 CAR30228.1 - 0.23 8.6 0.3 0.33 8.0 0.3 1.1 1 0 0 1 1 1 0 ssDNA binding protein Abhydrolase_1 PF00561.20 CAR30229.1 - 1e-21 77.8 0.1 3.7e-21 75.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CAR30229.1 - 3.6e-21 74.5 0.2 6.5e-21 73.7 0.2 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CAR30229.1 - 2e-05 24.0 0.0 0.099 11.9 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CAR30229.1 - 0.093 12.4 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) MF_alpha PF04648.12 CAR30230.1 - 2e-27 94.3 34.8 1.3e-06 28.5 3.5 4.2 4 0 0 4 4 4 4 Yeast mating factor alpha hormone MF_alpha_N PF05436.11 CAR30230.1 - 5.8e-21 74.2 0.1 8.5e-21 73.7 0.1 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus PMT_4TMC PF16192.5 CAR30230.1 - 0.23 11.0 8.6 13 5.3 0.0 3.9 1 1 3 4 4 4 0 C-terminal four TMM region of protein-O-mannosyltransferase Apidaecin PF00807.17 CAR30230.1 - 2 8.6 17.1 24 5.1 0.4 4.3 4 0 0 4 4 4 0 Apidaecin AMPK1_CBM PF16561.5 CAR30231.1 - 0.0099 16.1 1.3 0.029 14.6 1.2 1.9 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SIR4_SID PF16991.5 CAR30231.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.0 1 1 1 2 2 2 0 Sir4 SID domain DUF5484 PF17583.2 CAR30231.1 - 2 8.1 5.8 10 5.9 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5484) RRM_1 PF00076.22 CAR30232.1 - 8e-26 89.7 2.6 3.1e-08 33.3 0.2 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR30232.1 - 1.2e-11 44.3 0.0 0.0019 18.0 0.0 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CAR30232.1 - 0.0008 19.0 0.1 0.43 10.2 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CAR30232.1 - 0.18 11.9 0.0 0.5 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif Ribosomal_60s PF00428.19 CAR30232.1 - 10 6.8 6.6 47 4.7 2.0 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein CRIC_ras_sig PF10534.9 CAR30233.1 - 0.012 15.8 0.6 0.027 14.6 0.6 1.5 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras DUF5505 PF17610.2 CAR30233.1 - 0.035 14.1 0.6 0.09 12.8 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5505) Exonuc_VII_L PF02601.15 CAR30233.1 - 4.2 6.9 9.3 0.099 12.2 1.0 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit ParA PF10609.9 CAR30234.1 - 3.2e-94 315.0 0.0 3.7e-94 314.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CAR30234.1 - 2.1e-10 40.7 0.0 1.2e-09 38.2 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAR30234.1 - 1.7e-05 24.8 0.3 0.00022 21.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CAR30234.1 - 3.5e-05 23.2 0.0 5.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CAR30234.1 - 0.00025 20.3 0.4 0.0053 16.0 0.0 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 CAR30234.1 - 0.0075 16.2 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CAR30234.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.6 CAR30234.1 - 0.016 15.0 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 CAR30234.1 - 0.034 13.6 0.1 0.082 12.4 0.1 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ TsaE PF02367.17 CAR30234.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_NifH PF00142.18 CAR30234.1 - 0.099 12.1 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 CAR30234.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_23 PF13476.6 CAR30234.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAR30234.1 - 0.18 12.2 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 CAR30234.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 CAR30234.1 - 0.2 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Nucleoporin2 PF04096.14 CAR30235.1 - 1.5e-46 158.2 0.0 3e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 CAR30235.1 - 1.4e-36 126.1 0.5 2.8e-36 125.1 0.2 1.7 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 CAR30235.1 - 4.4e-09 37.1 53.7 1.2e-06 29.2 21.1 5.2 2 1 3 5 5 5 2 Nucleoporin FG repeat region Spc7 PF08317.11 CAR30236.1 - 2.6e-48 164.5 4.2 5e-48 163.6 4.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein SKA2 PF16740.5 CAR30236.1 - 3.1 7.6 7.4 4.6 7.1 0.6 3.1 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Ribosomal_L36 PF00444.18 CAR30237.1 - 1.7e-19 69.7 10.1 2e-19 69.5 10.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.17 CAR30237.1 - 0.012 15.4 1.4 0.016 15.0 1.4 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family WD40 PF00400.32 CAR30238.1 - 1.3e-10 41.7 26.0 5.6e-05 23.8 0.2 9.0 11 0 0 11 11 11 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CAR30238.1 - 0.077 11.7 3.3 0.72 8.5 0.5 3.5 4 1 1 5 5 5 0 Nup133 N terminal like YmzC PF14157.6 CAR30238.1 - 0.27 11.3 1.0 5.5 7.1 0.0 3.1 3 0 0 3 3 3 0 YmzC-like protein Hira PF07569.11 CAR30238.1 - 0.38 10.4 2.7 5.6 6.6 0.0 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split UCH_1 PF13423.6 CAR30239.1 - 2e-78 264.2 0.3 2.7e-78 263.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CAR30239.1 - 3.5e-19 69.9 0.0 7.4e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 CAR30239.1 - 1e-06 28.4 0.3 5.1e-06 26.2 0.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40_like PF17005.5 CAR30239.1 - 0.0032 16.8 0.1 0.0066 15.8 0.1 1.5 1 0 0 1 1 1 1 WD40-like domain SMODS PF18144.1 CAR30239.1 - 0.049 13.8 0.1 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain ANAPC4_WD40 PF12894.7 CAR30239.1 - 0.11 12.8 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain TCO89 PF10452.9 CAR30240.1 - 5e-112 375.8 53.0 6.6e-112 375.4 53.0 1.1 1 0 0 1 1 1 1 TORC1 subunit TCO89 Sec1 PF00995.23 CAR30241.1 - 1.3e-116 391.2 7.3 1.6e-116 390.9 7.3 1.1 1 0 0 1 1 1 1 Sec1 family PHD PF00628.29 CAR30242.1 - 5e-11 42.3 6.2 9.6e-11 41.4 6.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CAR30242.1 - 0.0044 16.5 4.0 0.0076 15.8 4.0 1.4 1 0 0 1 1 1 1 PHD-finger Anophelin PF10731.9 CAR30242.1 - 0.095 12.6 2.8 9.3 6.2 0.6 2.7 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito Metallophos PF00149.28 CAR30243.1 - 1.7e-36 126.7 0.0 2.7e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR30243.1 - 2e-15 56.9 0.1 3.2e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain AF-4 PF05110.13 CAR30243.1 - 2.6 6.0 10.2 21 3.0 11.7 1.6 2 0 0 2 2 2 0 AF-4 proto-oncoprotein RRM_1 PF00076.22 CAR30244.1 - 5e-15 55.1 0.0 8.1e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.11 CAR30245.1 - 1.3e-18 66.6 0.2 1.3e-18 66.6 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CAR30245.1 - 7.4e-07 28.9 0.2 2e-06 27.5 0.2 1.8 1 0 0 1 1 1 1 Homeodomain DUF2795 PF11387.8 CAR30245.1 - 0.3 11.3 2.5 2.8 8.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) Arrestin_N PF00339.29 CAR30246.1 - 0.0044 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Sugar_tr PF00083.24 CAR30247.1 - 2.1e-88 297.2 19.4 2.5e-88 296.9 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30247.1 - 5.6e-13 48.5 25.0 5.6e-13 48.5 25.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CAR30247.1 - 1e-05 24.3 10.9 0.0049 15.5 2.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein FPN1 PF06963.12 CAR30247.1 - 1.4 7.4 10.0 0.076 11.6 4.5 1.6 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Alpha-amylase PF00128.24 CAR30248.1 - 1.4e-113 379.8 0.0 2e-113 379.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CAR30248.1 - 0.0079 16.3 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain DAHP_synth_1 PF00793.20 CAR30249.1 - 1e-110 368.9 0.0 1.3e-110 368.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_biosynth PF00977.21 CAR30250.1 - 1.2e-45 155.8 0.4 8.9e-45 152.9 0.3 2.4 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.28 CAR30250.1 - 3.3e-23 82.4 0.0 6.7e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CAR30250.1 - 3.3e-07 30.1 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 CAR30250.1 - 7.1e-06 26.0 0.0 0.0082 16.0 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 CAR30250.1 - 0.0032 17.2 0.4 0.12 12.1 0.1 2.2 2 0 0 2 2 2 1 Peptidase C26 NMO PF03060.15 CAR30250.1 - 0.0033 16.8 0.2 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase DJ-1_PfpI PF01965.24 CAR30250.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family ThiG PF05690.14 CAR30250.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG RCC1 PF00415.18 CAR30251.1 - 3.1e-68 226.2 0.7 3.5e-13 50.0 0.1 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAR30251.1 - 9.5e-44 146.4 19.7 4.9e-10 38.9 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 CAR30251.1 - 0.011 16.2 1.0 18 5.8 0.0 3.7 3 0 0 3 3 3 0 SUKH-3 immunity protein PSK_trans_fac PF07704.11 CAR30252.1 - 0.015 16.1 0.0 0.029 15.1 0.0 1.5 1 0 0 1 1 1 0 Rv0623-like transcription factor Bystin PF05291.11 CAR30253.1 - 4.9e-122 406.8 0.0 4.9e-122 406.8 0.0 1.5 2 0 0 2 2 2 1 Bystin DnaB_2 PF07261.11 CAR30253.1 - 0.011 15.5 0.1 0.051 13.3 0.0 2.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment BUD22 PF09073.10 CAR30253.1 - 8 5.7 21.7 10 5.3 21.7 1.1 1 0 0 1 1 1 0 BUD22 MFS_1 PF07690.16 CAR30254.1 - 3.5e-34 118.3 36.8 3.5e-34 118.3 36.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR30254.1 - 4.4e-10 39.0 10.4 4.4e-10 39.0 10.4 3.3 2 2 0 2 2 2 1 Sugar (and other) transporter Use1 PF09753.9 CAR30255.1 - 6.3e-13 49.0 1.3 7.9e-13 48.7 1.3 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF5383 PF17355.2 CAR30255.1 - 0.12 12.7 1.3 0.17 12.2 0.1 1.8 2 1 0 2 2 2 0 Family of unknown function (DUF5383) HIP1_clath_bdg PF16515.5 CAR30255.1 - 0.19 12.3 6.8 0.15 12.7 1.4 2.3 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Peptidase_M20 PF01546.28 CAR30256.1 - 1.5e-29 103.2 0.0 3.5e-29 102.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR30256.1 - 3.2e-11 43.1 0.0 7.9e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain MMR_HSR1 PF01926.23 CAR30257.1 - 1.6e-16 60.4 0.1 5.2e-15 55.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR30257.1 - 2e-09 37.2 0.3 2.7e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR30257.1 - 4.2e-05 23.5 0.2 0.005 16.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CAR30257.1 - 0.0078 16.3 1.3 0.049 13.7 1.3 2.5 1 1 0 1 1 1 1 Dynamin family AIG1 PF04548.16 CAR30257.1 - 0.0098 15.2 0.1 0.024 14.0 0.1 1.6 1 0 0 1 1 1 1 AIG1 family AAA_18 PF13238.6 CAR30257.1 - 0.1 13.2 0.9 5.1 7.6 0.0 3.5 3 1 0 3 3 3 0 AAA domain WD40 PF00400.32 CAR30258.1 - 0.0074 17.1 7.6 12 6.9 0.2 5.8 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30258.1 - 0.0089 16.3 0.0 0.14 12.5 0.0 2.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.23 CAR30259.1 - 1.1e-75 254.6 0.4 2.4e-75 253.4 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CAR30259.1 - 2.2e-38 130.8 1.1 2.2e-38 130.8 1.1 2.9 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 CAR30259.1 - 2.4e-28 99.1 2.5 2.4e-28 99.1 2.5 3.6 5 0 0 5 5 3 1 HAND Helicase_C PF00271.31 CAR30259.1 - 1.7e-19 70.2 0.0 5.8e-19 68.5 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30259.1 - 4.5e-12 46.3 2.6 1.5e-11 44.6 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CAR30259.1 - 4.4e-09 35.9 0.0 1.5e-08 34.2 0.0 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CAR30259.1 - 2e-05 24.4 0.0 4.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CAR30259.1 - 0.00023 20.5 0.1 0.00065 19.0 0.1 1.8 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 CAR30259.1 - 0.00033 20.4 0.0 0.0009 19.0 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 CAR30259.1 - 0.0081 15.8 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 Myb_DNA-binding PF00249.31 CAR30259.1 - 0.027 14.7 2.1 4.8 7.5 0.0 3.5 3 0 0 3 3 2 0 Myb-like DNA-binding domain AAA_14 PF13173.6 CAR30259.1 - 0.027 14.5 0.6 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.6 CAR30259.1 - 0.068 13.6 0.5 0.42 11.0 0.5 2.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RSS_P20 PF11757.8 CAR30259.1 - 0.64 10.5 3.1 1.1 9.7 0.0 3.0 3 0 0 3 3 2 0 Suppressor of RNA silencing P21-like N-terminal domain RP-C PF03428.13 CAR30259.1 - 1.8 8.2 4.3 2.3 7.8 1.1 2.7 3 0 0 3 3 3 0 Replication protein C N-terminal domain GSHPx PF00255.19 CAR30260.1 - 7.5e-48 160.6 0.2 9.8e-48 160.2 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CAR30260.1 - 2.5e-05 24.2 0.1 8.6e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR30260.1 - 0.00011 22.0 0.0 0.00033 20.4 0.0 1.9 1 1 0 1 1 1 1 Redoxin WD40 PF00400.32 CAR30261.1 - 9.5e-18 64.3 12.4 0.0003 21.5 1.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30261.1 - 9.5e-11 41.9 1.1 0.013 15.7 0.1 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR30261.1 - 0.00044 19.3 0.1 10 5.0 0.0 3.8 3 1 0 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein YmzC PF14157.6 CAR30261.1 - 0.0039 17.2 0.0 0.59 10.3 0.0 3.0 3 0 0 3 3 3 1 YmzC-like protein Glycos_transf_4 PF00953.21 CAR30262.1 - 4.7e-31 107.9 11.7 4.7e-31 107.9 11.7 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 4 HD_3 PF13023.6 CAR30263.1 - 2.4e-38 131.7 0.1 3.1e-38 131.3 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CAR30263.1 - 3.3e-10 40.0 0.1 4.6e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CAR30263.1 - 4.2e-06 27.0 0.3 1e-05 25.7 0.3 1.6 1 1 0 1 1 1 1 HD domain Ribosomal_L27A PF00828.19 CAR30264.1 - 9.5e-22 78.0 0.0 1.4e-21 77.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sugar_tr PF00083.24 CAR30265.1 - 1.2e-100 337.6 10.1 5.3e-99 332.1 10.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30265.1 - 5e-36 124.3 16.0 7.5e-36 123.8 16.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR30265.1 - 1.6e-09 36.7 1.4 1.6e-09 36.7 1.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CAR30265.1 - 2.4e-06 27.1 1.3 2.4e-06 27.1 1.3 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 CAR30265.1 - 1.3e-05 24.0 19.9 9.2e-05 21.2 0.3 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein BT1 PF03092.16 CAR30265.1 - 0.96 7.6 7.7 0.056 11.7 1.9 1.8 2 0 0 2 2 2 0 BT1 family Zn_clus PF00172.18 CAR30266.1 - 5.3e-11 42.5 6.3 1.6e-10 40.9 6.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3405 PF11885.8 CAR30266.1 - 0.26 9.9 3.1 0.45 9.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) tRNA_bind PF01588.20 CAR30267.1 - 5.4e-28 96.9 0.0 1.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_6 PF17171.4 CAR30267.1 - 0.039 13.7 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TAF4 PF05236.14 CAR30267.1 - 0.14 11.9 9.4 0.23 11.2 9.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PAS PF00989.25 CAR30268.1 - 3.6e-14 52.7 0.0 7.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.18 CAR30268.1 - 9.3e-08 32.1 10.3 1.7e-07 31.2 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helo_like_N PF17111.5 CAR30268.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins EF-hand_7 PF13499.6 CAR30269.1 - 1.6e-10 41.3 0.8 2.1e-06 28.1 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR30269.1 - 2.8e-10 39.3 3.8 0.0006 19.5 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 CAR30269.1 - 3.4e-09 36.9 0.0 0.0013 19.0 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CAR30269.1 - 6.9e-09 34.6 5.5 0.0011 18.4 0.2 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CAR30269.1 - 2.2e-06 27.4 1.1 0.00046 20.0 0.2 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_14 PF17959.1 CAR30269.1 - 0.00084 19.6 0.1 0.75 10.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 CAR30269.1 - 0.031 14.2 0.1 5 7.0 0.1 2.6 1 1 1 2 2 2 0 Caleosin related protein GPHH PF16905.5 CAR30269.1 - 0.13 12.1 0.0 4.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_5 PF13202.6 CAR30269.1 - 1.5 8.5 5.4 1.3 8.6 0.2 2.9 3 0 0 3 3 3 0 EF hand Flagellin_N PF00669.20 CAR30271.1 - 0.022 14.9 1.5 0.026 14.6 0.8 1.4 1 1 0 1 1 1 0 Bacterial flagellin N-terminal helical region DEAD PF00270.29 CAR30272.1 - 1.1e-49 168.6 0.0 2.7e-49 167.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30272.1 - 1e-21 77.4 0.1 1e-21 77.4 0.1 2.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30272.1 - 6.7e-06 26.2 0.6 3e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4642 PF15484.6 CAR30272.1 - 0.038 14.2 0.2 0.038 14.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) Pox_MCEL PF03291.16 CAR30273.1 - 1.4e-100 336.7 0.1 1.4e-100 336.7 0.1 1.4 2 0 0 2 2 2 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CAR30273.1 - 2e-10 41.2 0.0 3.9e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR30273.1 - 1.1e-09 38.9 0.1 3.7e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR30273.1 - 5.6e-07 29.5 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR30273.1 - 6.4e-07 29.9 0.0 1.4e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR30273.1 - 1.9e-05 24.5 0.9 8.4e-05 22.4 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Cwf_Cwc_15 PF04889.12 CAR30273.1 - 0.0088 15.8 9.4 0.014 15.2 9.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NNMT_PNMT_TEMT PF01234.17 CAR30273.1 - 0.01 15.0 0.4 0.022 14.0 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family CMAS PF02353.20 CAR30273.1 - 0.023 14.0 0.0 0.064 12.5 0.0 1.7 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ret2_MD PF18528.1 CAR30273.1 - 4.3 7.8 5.3 1.1 9.7 1.9 1.7 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain AA_permease PF00324.21 CAR30274.1 - 4e-49 167.5 37.1 5.2e-49 167.1 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CAR30274.1 - 1.1e-15 57.7 8.6 5.3e-09 35.6 0.1 3.6 4 0 0 4 4 4 3 Solute carrier family 12 CUE PF02845.16 CAR30275.1 - 4.6e-10 39.0 0.0 4.5e-09 35.8 0.0 2.5 1 1 1 2 2 2 1 CUE domain UBA_4 PF14555.6 CAR30275.1 - 0.0033 17.2 0.0 0.0081 16.0 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain DMA PF03474.14 CAR30275.1 - 0.069 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif WD40 PF00400.32 CAR30277.1 - 6.3e-10 39.5 9.2 0.0012 19.6 0.3 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30277.1 - 7.9e-06 26.1 0.1 0.22 11.8 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR30277.1 - 0.042 13.7 0.9 0.29 11.0 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DASH_Dad3 PF08656.10 CAR30278.1 - 2.6e-25 88.3 0.3 2.8e-25 88.2 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 BLOC1_2 PF10046.9 CAR30278.1 - 0.078 13.3 0.0 0.089 13.1 0.0 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TAF6_C PF07571.13 CAR30279.1 - 8.6e-31 106.1 0.0 2.2e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CAR30279.1 - 5.8e-28 96.9 0.4 1.1e-27 96.0 0.4 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 CAR30279.1 - 0.0021 18.1 0.1 0.0049 16.9 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 CAR30279.1 - 0.0058 16.9 0.3 0.016 15.5 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAR30279.1 - 0.0083 16.5 0.2 0.0083 16.5 0.2 2.5 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 DUF348 PF03990.14 CAR30279.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain CLASP_N PF12348.8 CAR30279.1 - 0.063 12.8 0.2 0.64 9.5 0.2 2.2 1 1 0 1 1 1 0 CLASP N terminal TAF4 PF05236.14 CAR30279.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family CENP-S PF15630.6 CAR30279.1 - 0.078 13.4 0.8 0.3 11.5 0.1 2.3 3 0 0 3 3 3 0 CENP-S protein SLD3 PF08639.10 CAR30280.1 - 2.6e-42 145.3 21.4 9.7e-29 100.5 14.9 2.2 1 1 1 2 2 2 2 DNA replication regulator SLD3 Sld3_N PF18523.1 CAR30280.1 - 1.5e-30 105.7 1.5 3.5e-30 104.5 1.5 1.7 1 0 0 1 1 1 1 Sld3 N-terminal domain KH_1 PF00013.29 CAR30281.1 - 3.6e-38 129.2 8.4 2.6e-14 52.8 1.6 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CAR30281.1 - 7.3e-11 41.7 2.4 0.013 15.3 0.2 3.6 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 CAR30281.1 - 5.4e-07 29.4 0.4 0.042 13.7 0.1 2.8 2 1 1 3 3 3 2 KH domain KH_5 PF13184.6 CAR30281.1 - 0.0025 17.8 1.6 11 6.2 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain BCNT PF07572.12 CAR30282.1 - 9.3e-23 80.1 0.3 9.3e-23 80.1 0.3 2.4 3 1 1 4 4 4 1 Bucentaur or craniofacial development OPT PF03169.15 CAR30283.1 - 5.9e-150 500.8 15.6 7e-150 500.6 15.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PsaM PF07465.13 CAR30283.1 - 0.026 14.2 1.8 0.073 12.8 1.8 1.8 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) CBS PF00571.28 CAR30284.1 - 4.2e-26 91.2 2.4 2.9e-11 43.6 0.1 4.4 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.11 CAR30284.1 - 0.34 11.0 1.9 3.1 8.0 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain ANAPC4_WD40 PF12894.7 CAR30285.1 - 2.6e-12 46.9 2.1 0.0052 17.1 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR30285.1 - 5.1e-12 46.1 13.9 8.4e-05 23.3 0.3 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CAR30285.1 - 4.8e-06 25.8 0.0 0.00015 20.8 0.0 2.5 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CAR30285.1 - 3.7e-05 23.7 0.3 0.16 11.8 0.1 3.5 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ABC1 PF03109.16 CAR30286.1 - 1.7e-35 121.7 0.0 8.7e-35 119.5 0.0 2.1 2 0 0 2 2 2 1 ABC1 family Mis14 PF08641.12 CAR30286.1 - 0.00041 20.7 1.9 0.00088 19.6 1.9 1.5 1 0 0 1 1 1 1 Kinetochore protein Mis14 like OB_NTP_bind PF07717.16 CAR30287.1 - 7.6e-23 80.7 0.0 2.7e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CAR30287.1 - 2e-21 76.3 0.0 2e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAR30287.1 - 3.3e-12 46.7 0.0 9e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR30287.1 - 1.3e-08 34.9 0.4 2.2e-08 34.1 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR30287.1 - 6.4e-06 26.5 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CAR30287.1 - 3.9e-05 23.4 0.3 0.00011 21.9 0.3 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 CAR30287.1 - 0.0003 20.8 0.3 0.00065 19.7 0.3 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 CAR30287.1 - 0.00044 20.6 0.1 0.00092 19.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR30287.1 - 0.00083 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAR30287.1 - 0.0063 17.0 0.1 0.2 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CAR30287.1 - 0.016 15.2 0.0 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CAR30287.1 - 0.04 13.2 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CAR30287.1 - 0.06 12.9 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 CAR30287.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Nab2 PF11517.8 CAR30288.1 - 2e-43 146.8 0.1 3.5e-43 146.0 0.1 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.6 CAR30288.1 - 8.1e-21 73.7 67.7 8e-06 26.1 5.1 6.8 7 0 0 7 7 7 6 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 CAR30288.1 - 6.2e-17 61.2 8.2 6.2e-17 61.2 8.2 3.8 4 0 0 4 4 4 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 TFIIA PF03153.13 CAR30288.1 - 0.006 16.6 10.3 0.006 16.6 10.3 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2508 PF10704.9 CAR30288.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Halo_GVPC PF05465.13 CAR30288.1 - 0.094 13.0 0.2 0.18 12.1 0.2 1.4 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF4834 PF16118.5 CAR30288.1 - 5 8.2 5.7 4.4 8.3 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ribosomal_S5 PF00333.20 CAR30289.1 - 6e-26 90.2 2.4 6e-26 90.2 2.4 2.1 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CAR30289.1 - 2e-24 84.8 0.0 3.4e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF5353 PF17304.2 CAR30290.1 - 4.8e-05 23.0 0.7 9.8e-05 22.0 0.7 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5353) DUF883 PF05957.13 CAR30290.1 - 0.0069 17.0 8.0 0.15 12.7 1.2 2.3 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 CAR30290.1 - 2.7 8.1 9.4 5.2 7.2 9.4 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Mon1 PF03164.14 CAR30291.1 - 4.6e-141 470.5 0.1 6.1e-141 470.2 0.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 TMEM156 PF15106.6 CAR30291.1 - 0.098 12.1 0.1 0.25 10.7 0.1 1.6 1 0 0 1 1 1 0 TMEM156 protein family GATA PF00320.27 CAR30292.1 - 2e-14 52.9 6.6 3.5e-14 52.1 6.6 1.4 1 0 0 1 1 1 1 GATA zinc finger Glyco_hydro_31 PF01055.26 CAR30293.1 - 6.3e-131 437.6 0.2 1e-130 436.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CAR30293.1 - 1.2e-21 76.8 1.5 4.7e-21 74.9 0.1 2.7 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 CAR30293.1 - 6.6e-07 29.5 0.0 2.3e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) GIY-YIG PF01541.24 CAR30294.1 - 3.1e-12 46.6 0.0 6.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain DUF4451 PF14616.6 CAR30294.1 - 0.00048 20.3 1.9 0.0057 16.8 0.3 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4451) FANCL_C PF11793.8 CAR30294.1 - 0.024 14.8 4.8 0.06 13.5 4.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain T5orf172 PF10544.9 CAR30294.1 - 0.024 15.1 0.4 0.2 12.2 0.1 2.5 2 1 0 2 2 1 0 T5orf172 domain YacG PF03884.14 CAR30294.1 - 0.076 12.8 5.4 2.8 7.8 1.3 2.8 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG AWPM-19 PF05512.11 CAR30294.1 - 0.15 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 AWPM-19-like family Prok-RING_4 PF14447.6 CAR30294.1 - 0.2 11.6 5.2 4 7.4 0.1 3.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 PHD PF00628.29 CAR30294.1 - 1.1 9.2 5.9 0.88 9.5 2.7 2.5 2 1 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.6 CAR30294.1 - 1.2 9.2 8.3 6.2 6.9 4.4 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 CAR30294.1 - 1.3 9.4 11.9 2.3 8.6 7.9 2.8 2 1 0 2 2 2 0 Ring finger domain zf-H2C2_2 PF13465.6 CAR30294.1 - 3.3 8.3 8.0 7.4 7.2 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain AAA_2 PF07724.14 CAR30295.1 - 2e-34 119.2 1.5 3.8e-34 118.3 0.3 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CAR30295.1 - 7.1e-13 49.1 0.1 1.6e-12 48.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CAR30295.1 - 1.3e-07 31.5 0.2 4.7e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CAR30295.1 - 7.1e-06 26.1 0.0 2.2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR30295.1 - 3.9e-05 23.9 0.2 0.0008 19.7 0.2 2.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAR30295.1 - 9.2e-05 21.9 0.0 0.011 15.1 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CAR30295.1 - 0.00046 20.6 0.4 0.0023 18.3 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 CAR30295.1 - 0.00059 19.6 0.1 0.09 12.5 0.0 3.2 2 1 1 3 3 3 1 Sigma-54 interaction domain RuvB_N PF05496.12 CAR30295.1 - 0.003 17.3 0.0 0.0094 15.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CAR30295.1 - 0.0042 17.3 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAR30295.1 - 0.0043 16.8 0.2 0.019 14.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CAR30295.1 - 0.005 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain MCM PF00493.23 CAR30295.1 - 0.0062 15.7 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain IstB_IS21 PF01695.17 CAR30295.1 - 0.013 15.2 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 CAR30295.1 - 0.015 15.2 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 CAR30295.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CAR30295.1 - 0.019 15.4 0.4 0.058 13.9 0.4 2.1 1 1 0 1 1 1 0 ABC transporter DEAD PF00270.29 CAR30295.1 - 0.038 13.8 0.9 0.49 10.1 0.9 2.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 CAR30295.1 - 0.046 12.8 0.0 0.1 11.6 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 CAR30295.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CAR30295.1 - 0.05 13.6 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAR30295.1 - 0.082 13.3 0.1 0.52 10.7 0.0 2.4 3 0 0 3 3 2 0 RNA helicase PhoH PF02562.16 CAR30295.1 - 0.086 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 CAR30295.1 - 0.11 13.1 0.7 0.65 10.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain DUF3987 PF13148.6 CAR30295.1 - 0.19 10.7 1.3 6.6 5.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) Methyltransf_11 PF08241.12 CAR30296.1 - 0.00015 22.3 0.0 0.00032 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR30296.1 - 0.009 16.7 0.0 0.021 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR30296.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTHFR PF02219.17 CAR30297.1 - 1.3e-121 405.4 0.0 1.7e-121 404.9 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Tyr-DNA_phospho PF06087.12 CAR30298.1 - 5.1e-97 325.4 0.0 6e-97 325.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase AMP-binding PF00501.28 CAR30299.1 - 1e-72 245.1 0.0 1.4e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR30299.1 - 1.6e-18 67.4 0.2 5.5e-18 65.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transket_pyr PF02779.24 CAR30300.1 - 4.1e-47 160.2 0.0 9.4e-47 159.0 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CAR30300.1 - 6.5e-36 122.9 0.1 1.4e-35 121.9 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acatn PF13000.7 CAR30301.1 - 4.6e-254 844.0 11.8 5.3e-254 843.8 11.8 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Scs3p PF10261.9 CAR30302.1 - 1e-69 234.8 11.1 1.2e-69 234.5 11.1 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Med31 PF05669.12 CAR30303.1 - 3.2e-25 87.9 0.4 3.7e-25 87.8 0.4 1.1 1 0 0 1 1 1 1 SOH1 CPSase_L_D2 PF02786.17 CAR30304.1 - 3.1e-84 281.7 0.2 4.9e-84 281.1 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CAR30304.1 - 2.2e-68 229.9 0.0 4e-68 229.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CAR30304.1 - 3.3e-39 133.8 0.0 6.8e-39 132.8 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAR30304.1 - 2.1e-30 105.0 0.0 6.4e-30 103.4 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CAR30304.1 - 3.9e-26 92.2 0.0 7.6e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CAR30304.1 - 3.6e-20 71.6 8.2 5e-20 71.1 2.6 3.0 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CAR30304.1 - 3e-10 39.8 2.2 0.00033 20.4 0.2 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CAR30304.1 - 1e-07 31.7 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAR30304.1 - 4e-07 29.8 0.0 8.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CAR30304.1 - 6.1e-06 26.4 0.1 1.7e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.6 CAR30304.1 - 0.0007 18.9 0.0 0.0018 17.6 0.0 1.7 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 CAR30304.1 - 0.0012 18.1 0.4 0.036 13.3 0.0 2.6 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 CAR30304.1 - 0.0023 17.6 0.0 0.0052 16.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 CAR30304.1 - 0.0036 17.2 4.9 0.023 14.7 0.9 2.9 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 CAR30304.1 - 0.0038 17.9 0.3 3 8.6 0.1 2.9 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.11 CAR30304.1 - 0.041 13.3 0.2 0.079 12.4 0.2 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DASH_Duo1 PF08651.10 CAR30305.1 - 1.8e-23 82.1 0.2 1.8e-23 82.1 0.2 2.0 2 0 0 2 2 2 1 DASH complex subunit Duo1 IATP PF04568.12 CAR30305.1 - 3.8 8.0 7.0 2.1 8.8 3.0 2.4 2 1 1 3 3 3 0 Mitochondrial ATPase inhibitor, IATP APG12 PF04110.13 CAR30306.1 - 9.2e-27 93.3 0.0 1.5e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Kinetochor_Ybp2 PF08568.10 CAR30307.1 - 8.8e-147 490.3 16.1 1.1e-146 490.0 16.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.10 CAR30308.1 - 9e-08 32.0 0.0 9e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 HPC2 and ubinuclein domain TFIIA PF03153.13 CAR30308.1 - 0.0085 16.1 32.6 0.012 15.7 32.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CAR30308.1 - 1.4 7.5 32.7 1.6 7.3 32.7 1.2 1 0 0 1 1 1 0 Hamartin protein BCDHK_Adom3 PF10436.9 CAR30309.1 - 1.3e-29 103.2 0.4 2.4e-29 102.3 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CAR30309.1 - 1.3e-06 28.9 0.0 5.5e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.26 CAR30310.1 - 1.8e-48 163.7 0.1 2.3e-48 163.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR30310.1 - 0.0075 16.0 0.0 0.014 15.1 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CAR30310.1 - 0.033 14.5 0.1 0.092 13.0 0.1 1.7 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 CAR30310.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Leuk-A4-hydro_C PF09127.11 CAR30310.1 - 0.065 13.3 0.1 0.9 9.6 0.1 2.0 1 1 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal CBS PF00571.28 CAR30312.1 - 2.3e-17 63.2 1.0 0.0045 17.4 0.0 5.3 5 0 0 5 5 5 5 CBS domain FA_desaturase PF00487.24 CAR30313.1 - 1.6e-19 70.7 18.6 1.6e-19 70.7 18.6 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAR30313.1 - 4.5e-15 55.5 0.0 9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_7 PF13241.6 CAR30314.1 - 2.3e-27 95.5 0.0 5.4e-27 94.3 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CAR30314.1 - 1.9e-14 53.1 0.0 3.1e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CAR30314.1 - 4e-12 45.3 0.1 9e-12 44.2 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 CAR30314.1 - 0.0078 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RRM_1 PF00076.22 CAR30315.1 - 4.7e-41 138.5 0.0 1.1e-16 60.4 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EPL1 PF10513.9 CAR30315.1 - 0.0043 17.4 6.4 0.0065 16.9 6.4 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like Tub PF01167.18 CAR30315.1 - 0.017 14.9 4.9 0.024 14.4 4.9 1.2 1 0 0 1 1 1 0 Tub family PAT1 PF09770.9 CAR30315.1 - 0.04 12.2 19.3 0.054 11.8 19.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nup35_RRM_2 PF14605.6 CAR30315.1 - 0.072 13.1 0.1 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FliP PF00813.20 CAR30315.1 - 0.14 12.0 0.2 0.22 11.4 0.2 1.2 1 0 0 1 1 1 0 FliP family Ribosomal_L30_N PF08079.12 CAR30315.1 - 0.18 12.1 4.2 0.33 11.2 4.2 1.3 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain BORG_CEP PF14957.6 CAR30315.1 - 0.83 10.8 6.4 1.7 9.8 6.4 1.5 1 0 0 1 1 1 0 Cdc42 effector DUF4175 PF13779.6 CAR30315.1 - 0.89 7.4 21.9 1.2 6.9 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tho2 PF11262.8 CAR30315.1 - 1.2 8.2 12.9 2 7.5 12.9 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CPSF100_C PF13299.6 CAR30315.1 - 1.4 9.1 4.1 2.6 8.2 4.1 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CCDC53 PF10152.9 CAR30315.1 - 1.5 9.3 10.1 2.5 8.5 8.3 2.1 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex FAM76 PF16046.5 CAR30315.1 - 2.2 7.5 14.2 3.2 7.0 14.2 1.1 1 0 0 1 1 1 0 FAM76 protein DUF2464 PF10240.9 CAR30315.1 - 2.4 7.6 6.4 4.6 6.7 6.4 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 Neur_chan_memb PF02932.16 CAR30315.1 - 3.4 7.7 10.7 0.65 10.0 6.9 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 CAR30315.1 - 5.9 6.8 33.0 0.37 10.7 27.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CAR30315.1 - 8 5.6 10.0 12 5.0 10.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.8 CAR30315.1 - 8.2 6.0 31.8 14 5.2 31.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF2967 PF11179.8 CAR30316.1 - 0.0022 16.2 0.3 0.0033 15.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) EF-hand_9 PF14658.6 CAR30316.1 - 0.11 12.8 0.1 0.31 11.4 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain CHASE3 PF05227.13 CAR30316.1 - 1.2 9.1 7.5 0.75 9.7 5.0 1.9 2 0 0 2 2 2 0 CHASE3 domain Cornichon PF03311.14 CAR30317.1 - 1.9e-48 163.8 10.6 2.3e-48 163.5 10.6 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.11 CAR30317.1 - 0.044 13.9 0.1 0.086 12.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) HRI1 PF16815.5 CAR30318.1 - 7.2e-38 130.6 0.0 8.3e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 SNF2_N PF00176.23 CAR30319.1 - 2.4e-55 187.7 0.6 2.4e-55 187.7 0.6 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR30319.1 - 2.4e-17 63.3 0.1 1e-16 61.2 0.1 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30319.1 - 7.5e-06 26.0 0.0 4.2e-05 23.6 0.0 2.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 CAR30319.1 - 8.4e-06 25.6 6.0 2.9e-05 23.8 6.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR30319.1 - 1.4e-05 25.3 2.8 3.5e-05 24.1 2.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CAR30319.1 - 3.2e-05 23.8 1.0 7.7e-05 22.6 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAR30319.1 - 3.2e-05 23.8 3.8 7.2e-05 22.7 3.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CAR30319.1 - 0.00011 21.9 2.9 0.00033 20.5 2.9 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CAR30319.1 - 0.00029 20.6 2.0 0.00078 19.2 2.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR30319.1 - 0.00096 19.0 3.8 0.0022 17.8 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CAR30319.1 - 0.0021 17.8 0.0 0.012 15.4 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4_5 PF17121.5 CAR30319.1 - 0.06 13.2 1.1 4 7.4 1.7 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR30319.1 - 0.099 12.4 1.0 0.29 10.9 1.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger ICAT PF06384.11 CAR30319.1 - 0.47 10.7 4.9 1.7 9.0 0.0 3.5 3 0 0 3 3 3 0 Beta-catenin-interacting protein ICAT zf-RING_14 PF17978.1 CAR30319.1 - 1.1 9.8 4.1 1.1 9.7 2.0 2.2 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CAR30319.1 - 1.8 8.8 6.0 4 7.7 6.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cellulase PF00150.18 CAR30320.1 - 8.9e-15 54.9 0.1 2e-14 53.7 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NUDIX_4 PF14815.6 CAR30321.1 - 0.032 14.2 0.1 0.042 13.8 0.1 1.3 1 0 0 1 1 1 0 NUDIX domain DUF1708 PF08101.11 CAR30323.1 - 8.3e-142 473.3 8.3 2.1e-141 472.0 8.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 CAR30323.1 - 0.0012 18.7 0.0 0.0065 16.3 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain G_glu_transpept PF01019.21 CAR30324.1 - 1.4e-140 469.5 0.0 1.6e-140 469.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase GTP_EFTU PF00009.27 CAR30325.1 - 1.8e-59 200.6 0.8 2.3e-59 200.2 0.8 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAR30325.1 - 2.4e-28 98.7 0.0 4.8e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAR30325.1 - 2.6e-19 69.4 1.2 6.2e-19 68.2 1.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR30325.1 - 2.8e-05 24.2 0.1 5.5e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 CAR30325.1 - 0.0015 18.1 0.1 0.0015 18.1 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CAR30325.1 - 0.0075 16.2 0.3 0.02 14.8 0.1 1.7 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CAR30325.1 - 0.012 15.3 1.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_U32_C PF16325.5 CAR30325.1 - 0.03 14.6 0.2 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain zf-U1 PF06220.12 CAR30326.1 - 4.6e-16 58.3 2.3 1e-15 57.2 2.3 1.6 1 0 0 1 1 1 1 U1 zinc finger Stn1 PF10451.9 CAR30327.1 - 1e-34 119.7 0.0 1.5e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.7 CAR30327.1 - 5.6e-34 116.7 0.0 8.9e-34 116.0 0.0 1.3 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH CAF1C_H4-bd PF12265.8 CAR30327.1 - 0.17 12.2 0.1 0.37 11.1 0.1 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Transthyretin PF00576.21 CAR30328.1 - 1.3e-36 125.7 0.1 1.5e-36 125.4 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family DUF1904 PF08921.11 CAR30328.1 - 0.15 12.4 0.0 3 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) DDE_1 PF03184.19 CAR30329.1 - 7e-63 211.4 2.2 1.4e-62 210.4 2.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CAR30329.1 - 3.5e-15 55.8 0.1 8.2e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CAR30329.1 - 0.0023 17.6 0.1 0.0069 16.1 0.1 1.8 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 CAR30329.1 - 0.006 17.2 0.1 0.67 10.6 0.2 2.8 2 0 0 2 2 2 1 Homeodomain-like domain Clathrin PF00637.20 CAR30330.1 - 2.5e-24 85.8 2.6 1.7e-23 83.1 0.1 2.8 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 CAR30330.1 - 4.9e-05 23.6 0.6 0.00024 21.3 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 CAR30330.1 - 0.014 16.2 0.3 0.055 14.4 0.3 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat DUF4157 PF13699.6 CAR30330.1 - 0.055 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) DNA_pol_phi PF04931.13 CAR30330.1 - 0.34 8.9 11.4 0.55 8.3 11.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi SURF2 PF05477.11 CAR30330.1 - 1.6 8.4 11.4 2.8 7.6 11.4 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Na_trans_assoc PF06512.13 CAR30330.1 - 4.4 7.5 11.1 9.4 6.5 11.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated CENP-B_dimeris PF09026.10 CAR30330.1 - 6.9 7.1 12.6 21 5.6 12.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AF-4 PF05110.13 CAR30330.1 - 8.4 4.3 14.9 12 3.8 14.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop14 PF04147.12 CAR30330.1 - 8.6 4.4 18.9 13 3.8 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family Sec34 PF04136.15 CAR30331.1 - 3.1e-41 140.7 5.5 3.1e-41 140.7 5.5 3.9 4 1 0 4 4 4 1 Sec34-like family Exo70 PF03081.15 CAR30331.1 - 0.0038 16.3 0.1 0.0038 16.3 0.1 3.8 3 2 1 4 4 4 1 Exo70 exocyst complex subunit Laminin_II PF06009.12 CAR30331.1 - 0.009 16.0 1.0 6.9 6.7 0.0 3.3 3 0 0 3 3 3 2 Laminin Domain II DUF4485 PF14846.6 CAR30331.1 - 0.025 14.6 0.0 0.099 12.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) PP2C_C PF07830.13 CAR30331.1 - 0.1 13.1 0.0 0.59 10.6 0.0 2.4 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Sod_Fe_N PF00081.22 CAR30331.1 - 0.16 12.5 3.5 0.3 11.6 0.1 3.0 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Pet100 PF09803.9 CAR30332.1 - 1.3e-08 35.2 1.0 1.7e-08 34.8 0.2 1.6 2 0 0 2 2 2 1 Pet100 ATPase_gene1 PF09527.10 CAR30332.1 - 0.17 12.1 0.1 0.23 11.7 0.1 1.1 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter UPF0160 PF03690.13 CAR30333.1 - 8.3e-131 436.3 0.0 9.4e-131 436.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) AbiEi_2 PF09952.9 CAR30333.1 - 0.035 14.4 0.0 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system RhoGAP PF00620.27 CAR30334.1 - 9e-38 129.5 0.0 3e-37 127.8 0.0 2.0 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 CAR30334.1 - 1.7e-15 57.1 1.5 8.3e-15 54.9 0.4 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif RasGEF PF00617.19 CAR30334.1 - 2.6e-14 53.8 1.0 1.4e-12 48.2 0.2 3.5 2 0 0 2 2 2 1 RasGEF domain 60KD_IMP PF02096.20 CAR30335.1 - 8.4e-22 77.8 0.2 8.4e-22 77.8 0.2 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein PET122 PF05476.11 CAR30336.1 - 5.3e-116 386.5 0.5 6.1e-116 386.3 0.5 1.0 1 0 0 1 1 1 1 PET122 M-factor PF03855.13 CAR30337.1 - 0.066 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 M-factor UCH PF00443.29 CAR30338.1 - 8.6e-50 169.6 0.7 8.6e-50 169.6 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR30338.1 - 0.0015 18.2 4.3 0.0015 18.2 4.3 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Cas9_PI2 PF18070.1 CAR30338.1 - 0.045 14.5 0.3 0.19 12.5 0.3 2.1 1 0 0 1 1 1 0 CRISPR-Cas9 PI domain Senescence_reg PF04520.13 CAR30338.1 - 0.47 11.3 11.2 0.15 12.9 7.6 2.0 2 0 0 2 2 2 0 Senescence regulator GCIP PF13324.6 CAR30338.1 - 0.57 9.7 7.8 0.07 12.7 1.4 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting RnaseA PF00074.20 CAR30339.1 - 0.31 11.5 17.4 2.5 8.6 0.8 3.2 2 1 1 3 3 3 0 Pancreatic ribonuclease Glyco_hydro_65C PF03633.15 CAR30339.1 - 3.2 7.7 7.5 87 3.1 0.2 4.5 3 1 1 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain AAA_16 PF13191.6 CAR30340.1 - 0.00082 19.8 0.5 0.0015 18.9 0.1 1.6 2 0 0 2 2 2 1 AAA ATPase domain RecA PF00154.21 CAR30340.1 - 0.0045 16.5 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CAR30340.1 - 0.015 14.7 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 KaiC Rad51 PF08423.11 CAR30340.1 - 0.097 11.9 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Rad51 Metallophos PF00149.28 CAR30341.1 - 7.3e-38 131.1 0.2 8.9e-38 130.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CAR30341.1 - 0.0052 17.0 0.0 0.0077 16.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 CAR30341.1 - 0.052 13.2 0.1 0.12 12.0 0.1 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, N-terminal domain Nup54 PF13874.6 CAR30342.1 - 0.0048 17.0 0.2 0.0048 17.0 0.2 3.0 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 DUF4515 PF14988.6 CAR30342.1 - 0.018 14.8 1.7 0.018 14.8 1.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) SYCE1 PF15233.6 CAR30342.1 - 0.046 13.8 11.4 1 9.4 1.5 3.2 3 0 0 3 3 3 0 Synaptonemal complex central element protein 1 DUF773 PF05600.12 CAR30342.1 - 0.051 12.3 10.1 0.5 9.0 1.0 2.8 3 0 0 3 3 3 0 CDK5 regulatory subunit-associated protein 3 THOC7 PF05615.13 CAR30342.1 - 0.08 13.2 8.2 0.095 13.0 0.4 2.9 3 0 0 3 3 3 0 Tho complex subunit 7 Seryl_tRNA_N PF02403.22 CAR30342.1 - 0.37 11.1 10.3 0.35 11.1 0.6 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.6 CAR30342.1 - 0.45 10.9 12.3 2.5 8.5 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) FliE PF02049.18 CAR30342.1 - 2.4 8.4 5.4 6.8 6.9 0.8 3.1 3 1 0 3 3 3 0 Flagellar hook-basal body complex protein FliE DUF4407 PF14362.6 CAR30342.1 - 7.1 5.9 11.6 4.4 6.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) TBP PF00352.21 CAR30343.1 - 3.5e-67 222.4 0.2 9.9e-33 112.0 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CAR30343.1 - 5.8e-05 23.1 0.0 0.61 10.2 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CAR30343.1 - 0.04 13.7 0.1 0.27 11.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Cohesin_load PF10345.9 CAR30344.1 - 5.2e-75 253.1 26.2 6.9e-75 252.7 26.2 1.1 1 0 0 1 1 1 1 Cohesin loading factor Glyco_transf_20 PF00982.21 CAR30345.1 - 6.5e-143 476.8 0.4 9.2e-143 476.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CAR30345.1 - 4.5e-75 251.8 0.0 7.3e-75 251.1 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase STD1 PF17235.2 CAR30346.1 - 0.041 13.5 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 STD1/MTH1 PAP2_3 PF14378.6 CAR30347.1 - 2.1e-14 53.7 15.7 1.1e-11 44.8 3.3 3.2 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 CAR30347.1 - 3.1e-10 40.0 3.0 3.1e-10 40.0 3.0 2.9 2 2 0 2 2 2 1 PAP2 superfamily LSM PF01423.22 CAR30348.1 - 3.9e-20 71.3 0.0 4.3e-20 71.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain YhzD PF14120.6 CAR30348.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 YhzD-like protein SM-ATX PF14438.6 CAR30348.1 - 0.14 12.3 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain Acetyltransf_1 PF00583.25 CAR30349.1 - 3.2e-18 66.1 0.0 4.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR30349.1 - 2.7e-10 40.3 0.0 4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR30349.1 - 1.7e-05 24.9 0.0 0.00063 19.8 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR30349.1 - 1.8e-05 25.1 0.0 2.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR30349.1 - 0.0056 16.6 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CAR30349.1 - 0.0071 16.5 0.0 0.0093 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CAR30349.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zinc_ribbon_16 PF17034.5 CAR30350.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Zinc-ribbon like family RPEL PF02755.15 CAR30350.1 - 3.1 7.6 0.0 3.1 7.6 0.0 2.7 3 0 0 3 3 3 0 RPEL repeat UCH PF00443.29 CAR30351.1 - 3e-62 210.5 0.1 6.2e-62 209.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR30351.1 - 9.8e-22 78.0 0.4 9.4e-21 74.7 0.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CAR30351.1 - 2.1e-08 34.6 0.0 3.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 CAR30351.1 - 0.0011 18.6 1.7 0.003 17.3 1.7 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger BSD PF03909.17 CAR30352.1 - 2.8e-13 49.7 5.3 3.8e-13 49.2 1.0 2.9 3 0 0 3 3 3 1 BSD domain AGOG PF09171.10 CAR30352.1 - 0.017 14.5 0.2 0.27 10.5 0.0 2.6 2 1 1 3 3 3 0 N-glycosylase/DNA lyase Y_phosphatase2 PF03162.13 CAR30353.1 - 6.3e-56 188.5 0.4 7.8e-56 188.2 0.4 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR30353.1 - 0.05 13.6 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Asp_protease PF09668.10 CAR30354.1 - 1.2e-52 176.9 0.6 2e-52 176.2 0.2 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CAR30354.1 - 1.1e-21 77.2 0.1 2.4e-21 76.1 0.1 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CAR30354.1 - 3.2e-11 43.7 0.1 6.9e-11 42.7 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 CAR30354.1 - 7.5e-10 38.5 0.0 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 CAR30354.1 - 3.6e-05 23.5 0.1 0.00011 21.9 0.1 1.8 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CAR30354.1 - 8.2e-05 22.9 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease HhH-GPD PF00730.25 CAR30355.1 - 8.5e-15 55.1 0.0 1.3e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RuvB_C PF05491.13 CAR30355.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain COX15-CtaA PF02628.15 CAR30356.1 - 2.2e-117 391.8 3.5 2.7e-117 391.5 3.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 CAR30356.1 - 0.21 11.7 2.9 0.87 9.7 0.3 2.7 3 0 0 3 3 3 0 Fumarate reductase subunit C DUF747 PF05346.11 CAR30357.1 - 6.6e-83 278.8 18.9 1.3e-82 277.9 18.9 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF3382 PF11862.8 CAR30357.1 - 1.8 8.9 6.6 0.32 11.3 1.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) RPAP2_Rtr1 PF04181.13 CAR30358.1 - 1.6e-17 63.5 1.5 3e-17 62.7 1.5 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S13_N PF08069.12 CAR30360.1 - 3.2e-29 100.8 0.1 6e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CAR30360.1 - 7.2e-15 55.0 0.8 1.1e-14 54.4 0.4 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 Cofilin_ADF PF00241.20 CAR30361.1 - 2.2e-19 69.4 0.0 2.8e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Aminotran_1_2 PF00155.21 CAR30362.1 - 4e-65 220.3 0.0 4.8e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 CAR30362.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.19 CAR30362.1 - 0.049 12.6 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Met_gamma_lyase PF06838.11 CAR30362.1 - 0.18 10.3 0.0 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ABC_tran PF00005.27 CAR30363.1 - 8.4e-21 74.9 0.0 5.1e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAR30363.1 - 2.7e-06 27.4 0.8 0.0094 15.8 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF2067 PF09840.9 CAR30363.1 - 0.0078 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) AAA_29 PF13555.6 CAR30363.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 CAR30363.1 - 0.028 14.6 0.3 0.065 13.5 0.1 1.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ploopntkinase1 PF18748.1 CAR30363.1 - 0.085 12.4 0.0 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 DUF5393 PF17371.2 CAR30363.1 - 0.093 10.8 0.0 0.43 8.7 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5393) Mannosyl_trans3 PF11051.8 CAR30364.1 - 9.3e-71 238.4 0.1 1.3e-70 237.9 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative GDI PF00996.18 CAR30365.1 - 2.3e-227 754.7 0.1 2.6e-227 754.4 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CAR30365.1 - 0.0065 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain LSM PF01423.22 CAR30366.1 - 2.1e-18 65.8 0.2 2.6e-18 65.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CAR30366.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein zf-C2H2_10 PF16588.5 CAR30367.1 - 4.3e-15 55.1 4.9 6.7e-15 54.5 4.9 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger Ribosomal_60s PF00428.19 CAR30367.1 - 5.6 7.6 6.6 3.3 8.4 4.5 1.7 1 1 1 2 2 2 0 60s Acidic ribosomal protein UAF_Rrn10 PF05234.11 CAR30368.1 - 6.4e-42 142.6 0.0 7.3e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Methyltr_RsmB-F PF01189.17 CAR30369.1 - 1.1e-41 142.8 0.0 6.1e-41 140.3 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CAR30369.1 - 0.0019 18.3 0.1 0.0038 17.4 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase MCM PF00493.23 CAR30370.1 - 5.2e-102 339.7 0.0 7.6e-102 339.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR30370.1 - 3.2e-36 124.0 0.0 5.8e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 CAR30370.1 - 4.1e-27 95.3 28.5 4.1e-27 95.3 28.5 3.3 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 CAR30370.1 - 6.4e-26 90.6 0.2 1.9e-25 89.1 0.2 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAR30370.1 - 2.7e-12 47.2 0.0 8.5e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR30370.1 - 5.8e-09 35.6 0.0 6e-07 29.0 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAR30370.1 - 6.2e-08 32.7 0.0 1.5e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CAR30370.1 - 0.00016 21.6 0.0 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAR30370.1 - 0.0025 17.5 0.1 0.018 14.7 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 CAR30370.1 - 0.009 16.4 0.0 0.025 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CAR30370.1 - 0.038 13.7 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain SelR PF01641.18 CAR30370.1 - 0.095 12.8 0.1 0.75 9.9 0.1 2.1 2 0 0 2 2 2 0 SelR domain Aldedh PF00171.22 CAR30372.1 - 2.6e-158 527.3 0.0 3e-158 527.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CAR30372.1 - 0.0024 17.3 0.0 0.056 12.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Lon_C PF05362.13 CAR30373.1 - 3.7e-66 222.6 0.0 1e-65 221.2 0.0 1.8 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CAR30373.1 - 4.4e-39 134.5 1.3 1.3e-38 133.0 1.3 1.9 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CAR30373.1 - 2.4e-22 79.8 0.0 7.9e-22 78.1 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CAR30373.1 - 1.7e-06 28.3 1.3 3.3e-06 27.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 CAR30373.1 - 5e-06 26.4 0.0 1.9e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CAR30373.1 - 8.8e-06 25.8 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR30373.1 - 0.0001 22.6 0.0 0.002 18.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR30373.1 - 0.00056 20.3 0.0 0.19 12.1 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 CAR30373.1 - 0.0013 19.2 0.8 0.01 16.2 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CAR30373.1 - 0.0018 18.0 0.0 0.013 15.2 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CAR30373.1 - 0.0024 17.9 0.1 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 CAR30373.1 - 0.0025 16.8 0.0 0.006 15.5 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain IstB_IS21 PF01695.17 CAR30373.1 - 0.0029 17.4 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CAR30373.1 - 0.0095 16.5 2.9 0.011 16.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain SKI PF01202.22 CAR30373.1 - 0.031 14.4 0.0 0.1 12.7 0.0 2.0 1 0 0 1 1 1 0 Shikimate kinase RsgA_GTPase PF03193.16 CAR30373.1 - 0.052 13.4 0.4 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 CAR30373.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CAR30373.1 - 0.13 11.8 0.6 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CAR30373.1 - 0.22 11.6 1.7 7.7 6.6 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase ApoLp-III PF07464.11 CAR30373.1 - 0.31 11.1 10.2 0.27 11.3 6.9 2.6 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ABC_tran PF00005.27 CAR30373.1 - 5.9 7.4 7.1 1.2 9.6 0.1 3.2 3 1 0 3 3 3 0 ABC transporter CBFD_NFYB_HMF PF00808.23 CAR30374.1 - 4.3e-26 91.0 0.0 7.2e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAR30374.1 - 9.1e-05 22.8 1.5 0.00017 22.0 0.0 2.0 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CAR30374.1 - 0.026 14.6 0.0 0.041 14.0 0.0 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Rft-1 PF04506.13 CAR30375.1 - 1.6e-207 690.4 32.5 1.8e-207 690.2 32.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 CAR30375.1 - 0.96 8.8 36.4 3.1 7.1 10.2 4.1 2 2 1 3 3 3 0 Polysaccharide biosynthesis protein Exo_endo_phos PF03372.23 CAR30376.1 - 4.8e-14 52.5 0.0 6.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CAR30376.1 - 4e-09 36.4 2.6 8e-09 35.5 2.6 1.5 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CAR30376.1 - 0.0014 18.5 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase DIT1_PvcA PF05141.12 CAR30376.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein PPV_E2_N PF00508.17 CAR30377.1 - 0.097 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 E2 (early) protein, N terminal Sortilin-Vps10 PF15902.5 CAR30378.1 - 1.5e-196 653.5 12.3 1.1e-142 476.0 4.3 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CAR30378.1 - 4.8e-66 222.3 17.2 5.8e-38 130.9 6.7 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR_2 PF13088.6 CAR30378.1 - 5.3e-05 22.7 0.1 6.2 6.0 0.0 5.0 6 0 0 6 6 6 2 BNR repeat-like domain BNR PF02012.20 CAR30378.1 - 0.0018 18.0 51.4 0.33 11.1 0.3 12.0 12 0 0 12 12 12 4 BNR/Asp-box repeat CHB_HEX_C PF03174.13 CAR30378.1 - 0.0023 17.9 3.6 3.9 7.5 0.0 4.6 4 1 1 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain preSET_CXC PF18264.1 CAR30378.1 - 0.16 12.5 9.5 1.8 9.1 1.9 2.7 2 0 0 2 2 2 0 CXC domain Mo-co_dimer PF03404.16 CAR30378.1 - 0.65 10.0 3.1 11 6.0 0.0 4.2 4 1 1 5 5 5 0 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.25 CAR30379.1 - 1.8e-67 227.5 0.0 2.1e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30379.1 - 1.5e-28 99.8 0.0 2.3e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR30379.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAR30379.1 - 0.0031 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR30379.1 - 0.0032 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAR30379.1 - 0.044 13.4 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CAR30379.1 - 0.11 12.1 0.1 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NDUF_B4 PF07225.12 CAR30379.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) AcetylCoA_hydro PF02550.15 CAR30380.1 - 2.7e-60 203.8 0.0 4.4e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CAR30380.1 - 1.7e-42 144.9 0.0 2.8e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.12 CAR30380.1 - 0.0086 15.0 0.3 0.043 12.7 0.2 1.9 2 0 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) Acid_PPase PF12689.7 CAR30381.1 - 8.1e-47 159.2 0.0 9.6e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HSP70 PF00012.20 CAR30382.1 - 1.2e-260 865.9 7.6 1.4e-260 865.7 7.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR30382.1 - 6.6e-18 64.6 0.0 1.1e-16 60.6 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CAR30382.1 - 0.0031 17.3 0.0 0.0081 15.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CAR30382.1 - 0.0057 15.9 0.1 0.018 14.3 0.1 1.9 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase FtsA PF14450.6 CAR30382.1 - 0.039 14.4 0.9 15 6.1 0.0 3.4 3 1 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 CAR30382.1 - 0.044 13.3 0.1 7.5 6.0 0.1 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TMCO5 PF14992.6 CAR30382.1 - 0.14 11.7 7.1 0.27 10.8 7.1 1.3 1 0 0 1 1 1 0 TMCO5 family UPF0121 PF03661.13 CAR30383.1 - 1.2e-28 100.1 4.6 1.6e-28 99.7 4.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) SHNi-TPR PF10516.9 CAR30384.1 - 1.4e-16 59.6 4.6 1.8e-15 56.1 0.1 3.7 4 0 0 4 4 4 1 SHNi-TPR TPR_12 PF13424.6 CAR30384.1 - 5.6e-05 23.3 0.9 0.0081 16.4 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAR30384.1 - 0.0018 18.1 1.2 0.019 14.8 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR30384.1 - 0.008 16.3 4.2 0.049 13.9 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR30384.1 - 0.012 15.7 6.2 0.037 14.1 0.0 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR30384.1 - 0.073 13.1 2.6 25 5.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR30384.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Septin PF00735.18 CAR30385.1 - 4.5e-107 357.5 0.7 5.7e-107 357.2 0.0 1.5 2 0 0 2 2 2 1 Septin AAA_16 PF13191.6 CAR30385.1 - 3.5e-05 24.2 0.1 0.00032 21.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR30385.1 - 0.00054 19.9 4.1 0.02 14.8 0.0 3.0 4 0 0 4 4 4 1 RsgA GTPase MMR_HSR1 PF01926.23 CAR30385.1 - 0.0036 17.4 0.1 0.0036 17.4 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR30385.1 - 0.0047 16.5 0.7 0.62 9.6 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CAR30385.1 - 0.0095 16.5 2.6 0.34 11.4 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Exonuc_VII_L PF02601.15 CAR30385.1 - 0.012 15.2 10.9 0.018 14.7 10.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lipocalin PF00061.23 CAR30385.1 - 0.016 15.4 2.0 0.024 14.9 1.1 1.7 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family AAA_22 PF13401.6 CAR30385.1 - 0.054 13.8 0.5 0.17 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CAR30385.1 - 0.25 11.4 0.1 0.25 11.4 0.1 3.2 2 2 1 3 3 3 0 Dynamin family Strep_SA_rep PF06696.11 CAR30385.1 - 1.7 8.8 10.5 0.33 11.0 3.4 2.5 1 1 1 2 2 2 0 Streptococcal surface antigen repeat FapA PF03961.13 CAR30385.1 - 2.6 6.6 12.8 4.3 5.8 12.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_SHD PF08518.11 CAR30386.1 - 3.3e-24 84.2 9.4 1.8e-12 46.6 0.5 3.4 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 CAR30386.1 - 1.4e-05 25.2 0.3 1.4e-05 25.2 0.3 3.0 3 0 0 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term CENP-F_leu_zip PF10473.9 CAR30386.1 - 0.00045 20.2 13.7 0.00045 20.2 13.7 4.1 4 1 1 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1192 PF06698.11 CAR30386.1 - 1.5 8.9 6.3 1.7 8.8 2.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) V_ATPase_I PF01496.19 CAR30386.1 - 2.1 6.2 7.8 7.8 4.3 7.8 2.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.8 CAR30386.1 - 5.2 7.1 26.6 21 5.2 10.4 3.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TolA_bind_tri PF16331.5 CAR30386.1 - 6.2 7.0 15.8 0.59 10.2 2.6 3.2 3 0 0 3 3 3 0 TolA binding protein trimerisation Ribonucleas_3_3 PF14622.6 CAR30387.1 - 1.6e-19 70.3 0.0 2.7e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CAR30387.1 - 0.0013 19.3 0.1 0.0044 17.6 0.1 1.9 1 1 0 1 1 1 1 Ribonuclease III domain DEAD PF00270.29 CAR30388.1 - 7.4e-42 143.1 0.6 2.2e-41 141.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30388.1 - 2.3e-32 111.6 0.6 3.3e-28 98.2 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30388.1 - 4.8e-05 23.4 0.0 4.8e-05 23.4 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR30388.1 - 0.2 11.9 0.6 1 9.6 0.6 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_G PF04718.15 CAR30389.1 - 4.1e-29 101.4 0.3 4.8e-29 101.1 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit TcA_TcB_BD PF18276.1 CAR30389.1 - 0.041 13.0 0.0 0.046 12.8 0.0 1.0 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain DAHP_synth_1 PF00793.20 CAR30389.1 - 0.077 11.9 0.0 0.12 11.2 0.0 1.3 1 1 0 1 1 1 0 DAHP synthetase I family MCM PF00493.23 CAR30390.1 - 4e-101 336.8 0.0 6.4e-101 336.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR30390.1 - 1.3e-37 128.5 1.1 1.3e-37 128.5 1.1 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CAR30390.1 - 7.5e-29 100.0 5.9 1.2e-28 99.3 4.4 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CAR30390.1 - 3.3e-17 63.0 3.6 1.6e-16 60.8 3.6 2.3 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CAR30390.1 - 1.4e-06 28.3 0.0 9.7e-06 25.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CAR30390.1 - 4.3e-06 26.3 0.0 0.00019 20.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAR30390.1 - 0.0015 18.4 0.0 0.0079 16.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAR30390.1 - 0.072 12.8 0.3 3.1 7.5 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Thymidylate_kin PF02223.17 CAR30390.1 - 0.11 12.1 1.4 0.33 10.6 0.0 2.5 3 0 0 3 3 3 0 Thymidylate kinase CAF1A PF12253.8 CAR30391.1 - 9.5e-21 73.8 9.8 9.5e-21 73.8 9.8 3.8 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A Csm1_N PF18504.1 CAR30392.1 - 0.00024 21.4 2.5 0.00069 19.9 1.1 2.5 2 0 0 2 2 2 1 Csm1 N-terminal domain GAS PF13851.6 CAR30392.1 - 0.00096 18.6 2.0 0.00096 18.6 2.0 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF4515 PF14988.6 CAR30392.1 - 0.0011 18.9 1.1 0.0011 18.9 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4515) ANTH PF07651.16 CAR30392.1 - 0.0017 17.4 0.4 0.0035 16.4 0.4 1.4 1 0 0 1 1 1 1 ANTH domain Golgin_A5 PF09787.9 CAR30392.1 - 0.009 15.5 2.7 0.047 13.2 0.5 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 5 Bap31_Bap29_C PF18035.1 CAR30392.1 - 0.032 14.2 3.0 0.032 14.2 3.0 2.7 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Cnn_1N PF07989.11 CAR30392.1 - 0.88 9.8 6.4 0.14 12.3 0.6 2.6 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Mss4 PF04421.13 CAR30393.1 - 2e-16 59.9 0.0 2.1e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Mss4 protein YscJ_FliF PF01514.17 CAR30393.1 - 0.17 11.5 0.0 0.23 11.1 0.0 1.1 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family eIF-6 PF01912.18 CAR30394.1 - 6.3e-82 273.7 0.5 8e-82 273.4 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family zf-C2H2 PF00096.26 CAR30395.1 - 3.9e-12 45.9 8.9 5.6e-06 26.5 1.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR30395.1 - 1.2e-07 31.9 7.4 0.0011 19.6 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR30395.1 - 3.6e-06 27.1 11.0 0.0035 17.7 0.5 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CAR30395.1 - 1.1e-05 25.3 3.7 0.0018 18.2 0.6 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CAR30395.1 - 0.021 14.7 5.2 1.8 8.6 0.1 2.5 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 CAR30395.1 - 0.026 14.4 0.5 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-met PF12874.7 CAR30395.1 - 0.027 14.8 1.9 0.14 12.6 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAR30395.1 - 0.044 14.1 0.7 0.71 10.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FAM75 PF14650.6 CAR30395.1 - 0.061 12.9 7.6 0.081 12.5 7.6 1.1 1 0 0 1 1 1 0 FAM75 family zf-BED PF02892.15 CAR30395.1 - 0.29 11.2 5.1 1 9.5 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger DUF4666 PF15697.5 CAR30395.1 - 0.6 10.8 4.2 11 6.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Mito_carr PF00153.27 CAR30396.1 - 1.8e-72 239.4 2.4 1e-24 86.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR30396.1 - 0.00033 19.9 0.3 2.1 7.4 0.1 3.5 2 1 1 3 3 3 2 Gammaproteobacterial serine protease B12D PF06522.11 CAR30397.1 - 0.0003 20.5 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Xan_ur_permease PF00860.20 CAR30398.1 - 2.3e-58 197.8 31.9 3.5e-58 197.2 31.9 1.2 1 0 0 1 1 1 1 Permease family DUF3169 PF11368.8 CAR30398.1 - 0.16 11.5 2.9 0.15 11.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Transcrip_reg PF01709.20 CAR30399.1 - 3.9e-81 272.0 0.1 4.5e-81 271.8 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator ATP-synt_F PF01990.17 CAR30400.1 - 1.6e-32 111.7 0.0 1.8e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit fn3_2 PF16893.5 CAR30401.1 - 1.7e-36 124.3 0.2 3.1e-36 123.4 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CAR30401.1 - 1.6e-22 79.2 0.1 2.6e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CAR30401.1 - 9.7e-11 41.9 0.0 2.6e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CAR30401.1 - 1.9e-08 34.1 0.0 3.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 CAR30401.1 - 0.00045 20.4 0.1 0.0014 18.8 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) PT PF04886.12 CAR30401.1 - 0.0016 18.0 24.6 0.13 11.8 18.3 3.4 1 1 1 2 2 2 1 PT repeat BRCT_2 PF16589.5 CAR30401.1 - 0.014 15.8 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 CAR30401.1 - 0.017 15.4 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 Fibronectin type III domain LIG3_BRCT PF16759.5 CAR30401.1 - 0.051 13.9 0.1 0.19 12.1 0.1 2.1 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Aminotran_3 PF00202.21 CAR30402.1 - 3.9e-103 345.3 0.0 4.8e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pyridox_oxase_2 PF12766.7 CAR30403.1 - 9.2e-32 109.6 0.1 1.6e-31 108.8 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase tRNA_bind PF01588.20 CAR30404.1 - 4.2e-15 55.6 0.0 6.3e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Ras PF00071.22 CAR30405.1 - 1.8e-50 170.7 0.1 2.2e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR30405.1 - 3.8e-17 62.6 0.0 8.3e-17 61.5 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR30405.1 - 8e-08 31.9 0.1 9.7e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR30405.1 - 2.4e-05 24.0 0.1 4.7e-05 23.0 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR30405.1 - 0.0006 19.8 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR30405.1 - 0.0069 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gly_transf_sug PF04488.15 CAR30406.1 - 4.2e-15 56.2 0.0 1e-14 54.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Isochorismatase PF00857.20 CAR30407.1 - 2.8e-25 89.5 0.0 5.1e-25 88.6 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family NUC153 PF08159.12 CAR30409.1 - 2.3e-11 43.3 4.4 4.4e-11 42.4 4.4 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 CAR30409.1 - 0.0032 18.3 1.4 3.1 8.8 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat V-SNARE_C PF12352.8 CAR30410.1 - 0.41 11.0 9.4 0.99 9.7 0.2 3.6 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Ecl1 PF12855.7 CAR30411.1 - 1.9e-09 38.9 1.1 2.2e-09 38.7 1.1 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-C2H2 PF00096.26 CAR30412.1 - 2.1e-07 31.0 16.4 0.00078 19.8 1.9 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR30412.1 - 5.6e-06 26.5 20.2 1.7e-05 25.0 3.5 3.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR30412.1 - 0.0002 21.9 12.5 0.023 15.5 2.2 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAR30412.1 - 0.16 12.0 3.8 2.5 8.2 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CAR30412.1 - 2.7 8.0 5.5 4.5 7.3 0.6 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 CAR30412.1 - 4.8 7.9 5.6 0.52 11.0 0.1 2.3 3 0 0 3 3 3 0 FOXP coiled-coil domain TBPIP PF07106.13 CAR30414.1 - 5e-25 87.2 1.8 6.3e-25 86.9 0.3 2.0 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Oberon_cc PF16312.5 CAR30414.1 - 0.017 15.1 2.9 0.017 15.1 2.9 1.8 2 0 0 2 2 2 0 Coiled-coil region of Oberon APG17 PF04108.12 CAR30414.1 - 0.073 12.2 4.9 0.044 12.9 2.5 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 MCD_N PF17408.2 CAR30414.1 - 2.5 8.3 5.4 22 5.3 1.1 3.4 2 1 1 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain Uricase PF01014.18 CAR30415.1 - 3.8e-66 221.3 0.7 9.4e-35 119.7 0.8 2.0 2 0 0 2 2 2 2 Uricase DUF1279 PF06916.13 CAR30416.1 - 5.6e-24 84.5 0.0 1.1e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) AGA2 PF17366.2 CAR30417.1 - 4.5e-26 90.3 6.0 7.2e-26 89.7 6.0 1.3 1 0 0 1 1 1 1 A-agglutinin-binding subunit Aga2 Ribosomal_L24e PF01246.20 CAR30418.1 - 1.8e-29 101.7 0.2 1.8e-29 101.7 0.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.12 CAR30418.1 - 0.049 13.2 3.0 0.061 12.9 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) UNC-79 PF14776.6 CAR30418.1 - 0.73 8.5 2.4 0.86 8.3 2.4 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF4718 PF15842.5 CAR30418.1 - 0.98 9.2 6.8 1.4 8.7 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) DDHD PF02862.17 CAR30418.1 - 2 8.5 7.1 2.4 8.3 7.1 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 CAR30418.1 - 7.4 5.7 5.0 8.5 5.5 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CAR30418.1 - 7.7 6.3 12.1 9.2 6.0 12.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L7Ae PF01248.26 CAR30419.1 - 4.5e-24 84.0 0.1 5e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CHCH PF06747.13 CAR30420.1 - 5.3e-05 23.2 2.2 0.00013 22.0 2.3 1.6 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 CAR30420.1 - 0.02 15.2 1.9 0.029 14.7 1.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CAR30420.1 - 0.038 14.0 1.7 0.061 13.3 1.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 CAR30420.1 - 0.074 13.1 1.7 0.098 12.7 1.7 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like tRNA-synt_2 PF00152.20 CAR30421.1 - 6.2e-77 258.7 1.8 7.8e-77 258.4 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR30421.1 - 8.1e-07 28.9 0.2 1.6e-06 28.0 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lipase_GDSL_3 PF14606.6 CAR30421.1 - 0.29 11.3 4.8 0.67 10.1 1.8 2.4 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DDHD PF02862.17 CAR30421.1 - 0.95 9.6 3.4 1.5 8.9 3.4 1.4 1 0 0 1 1 1 0 DDHD domain Hypoth_Ymh PF09509.10 CAR30421.1 - 1.6 8.6 6.1 0.78 9.6 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) NARP1 PF12569.8 CAR30421.1 - 2.1 7.1 11.0 3.3 6.5 11.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Asp-B-Hydro_N PF05279.11 CAR30421.1 - 3.6 7.6 12.6 6.6 6.7 12.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RasGEF PF00617.19 CAR30422.1 - 8.6e-56 188.9 1.2 1.4e-55 188.2 0.4 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CAR30422.1 - 2.8e-19 69.3 0.0 2.8e-19 69.3 0.0 2.7 2 1 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 CAR30422.1 - 4.6e-10 39.2 0.1 3.8e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CAR30422.1 - 2.1e-09 36.9 0.1 5.4e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAR30422.1 - 1.8e-07 30.7 0.3 5.3e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 SH3 domain GRIP PF01465.20 CAR30423.1 - 5.2e-14 51.9 0.2 1.5e-13 50.4 0.2 1.9 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 CAR30423.1 - 8.9e-07 28.1 20.9 8.9e-07 28.1 20.9 7.1 2 2 5 7 7 7 5 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CAR30423.1 - 0.00021 21.4 23.0 0.00021 21.4 23.0 9.0 2 2 7 9 9 9 5 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 CAR30423.1 - 0.0014 18.1 17.1 0.0014 18.1 17.1 6.3 1 1 3 4 4 4 2 Domain of unknown function (DUF4407) Sec8_exocyst PF04048.14 CAR30423.1 - 0.0056 16.6 10.8 0.0056 16.6 10.8 8.7 3 2 6 9 9 9 1 Sec8 exocyst complex component specific domain ATG16 PF08614.11 CAR30423.1 - 0.083 13.1 140.2 0.099 12.9 15.0 7.4 1 1 5 6 6 6 0 Autophagy protein 16 (ATG16) GAS PF13851.6 CAR30423.1 - 8 5.8 158.1 0.13 11.6 14.8 7.4 2 2 5 7 7 7 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CAR30423.1 - 9.9 6.2 161.3 0.12 12.4 24.4 8.8 2 2 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Methyltransf_11 PF08241.12 CAR30424.1 - 5.9e-19 68.5 0.0 1.1e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR30424.1 - 7.7e-18 65.0 0.0 3.4e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR30424.1 - 1.8e-13 51.1 0.0 3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR30424.1 - 2.9e-09 36.6 0.0 4.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CAR30424.1 - 4.3e-09 36.3 0.0 7.2e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR30424.1 - 1.8e-08 34.4 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAR30424.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain SAP PF02037.27 CAR30424.1 - 0.1 12.4 0.1 0.45 10.3 0.0 2.0 2 0 0 2 2 2 0 SAP domain Methyltransf_15 PF09445.10 CAR30424.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NodS PF05401.11 CAR30424.1 - 0.14 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Polysacc_deac_1 PF01522.21 CAR30425.1 - 1.7e-23 82.8 0.0 3e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase UQ_con PF00179.26 CAR30426.1 - 6.9e-34 116.5 0.0 8.6e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR30426.1 - 0.16 12.2 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain OTCace PF00185.24 CAR30427.1 - 3.5e-47 160.4 0.2 5.7e-47 159.7 0.2 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CAR30427.1 - 3.5e-42 143.9 0.1 6.8e-42 143.0 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RNA_lig_T4_1 PF09511.10 CAR30428.1 - 1e-78 264.2 0.0 1.9e-78 263.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 CAR30428.1 - 1.6e-72 243.0 0.0 4.4e-72 241.6 0.0 1.8 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 CAR30428.1 - 7.6e-57 192.7 0.1 1.1e-56 192.1 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain Exo70 PF03081.15 CAR30429.1 - 2.1e-87 293.6 4.7 3.7e-87 292.8 4.7 1.4 1 0 0 1 1 1 1 Exo70 exocyst complex subunit NAS PF03059.16 CAR30429.1 - 0.027 13.8 0.1 1.2 8.4 0.0 2.8 3 0 0 3 3 3 0 Nicotianamine synthase protein Arrestin_C PF02752.22 CAR30430.1 - 6e-16 59.1 0.1 9e-15 55.3 0.1 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CAR30430.1 - 9.1e-10 38.8 0.0 7.4e-07 29.3 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain ddrB-ParB PF18763.1 CAR30430.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain Vps51 PF08700.11 CAR30431.1 - 2.5e-11 43.5 2.5 2.9e-11 43.3 1.6 1.6 1 1 1 2 2 2 1 Vps51/Vps67 SLATT_5 PF18160.1 CAR30431.1 - 1.6 8.0 6.5 0.58 9.5 0.9 1.9 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 EF-hand_4 PF12763.7 CAR30432.1 - 0.00042 20.2 0.0 0.00098 19.0 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF3808 PF10300.9 CAR30433.1 - 1.1e-167 558.6 2.0 1.3e-167 558.4 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CAR30433.1 - 0.0033 17.5 2.1 0.75 10.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR30433.1 - 0.02 15.5 0.8 1.7 9.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAR30433.1 - 0.029 14.9 1.5 1.5 9.4 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CAR30433.1 - 0.044 13.4 1.3 0.12 12.0 0.4 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF3369 PF11849.8 CAR30433.1 - 0.068 13.4 0.8 0.12 12.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) IBR PF01485.21 CAR30434.1 - 8.9e-14 51.5 45.5 1.6e-08 34.7 12.3 4.5 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CAR30434.1 - 7.3e-06 25.8 15.0 7.3e-06 25.8 15.0 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR30434.1 - 0.0073 16.1 8.5 0.0073 16.1 8.5 4.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) DUF1810 PF08837.11 CAR30434.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1810) Actin PF00022.19 CAR30435.1 - 1.2e-96 323.8 0.0 7.6e-96 321.2 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAR30435.1 - 0.097 11.5 0.0 0.34 9.7 0.0 1.8 3 0 0 3 3 3 0 MreB/Mbl protein E3_UFM1_ligase PF09743.9 CAR30435.1 - 0.2 11.2 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 Mitofilin PF09731.9 CAR30436.1 - 3.7e-41 141.7 17.5 2e-33 116.2 17.4 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein tRNA-synt_His PF13393.6 CAR30436.1 - 5.7 6.1 10.9 0.88 8.8 4.5 2.4 1 1 0 2 2 2 0 Histidyl-tRNA synthetase Ric8 PF10165.9 CAR30437.1 - 0.002 17.3 0.0 0.73 8.8 0.0 2.1 2 0 0 2 2 2 2 Guanine nucleotide exchange factor synembryn Ras PF00071.22 CAR30438.1 - 7.1e-54 181.8 0.1 8.6e-54 181.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR30438.1 - 1.1e-34 119.3 0.0 2e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR30438.1 - 6.2e-13 48.6 0.0 7.8e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR30438.1 - 6.8e-05 22.9 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR30438.1 - 9.2e-05 22.4 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CAR30438.1 - 9.8e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR30438.1 - 0.00026 20.6 0.0 0.00055 19.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CAR30438.1 - 0.01 15.0 0.1 0.11 11.7 0.1 1.8 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 CAR30438.1 - 0.013 15.8 0.0 0.019 15.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CAR30438.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein KH_1 PF00013.29 CAR30439.1 - 1.7e-81 268.0 28.4 1.2e-13 50.7 0.5 12.1 12 0 0 12 12 12 9 KH domain KH_2 PF07650.17 CAR30439.1 - 2.5e-10 40.0 17.4 0.0015 18.3 0.7 7.5 5 1 1 6 6 6 4 KH domain KH_4 PF13083.6 CAR30439.1 - 9.3e-08 31.8 13.8 0.1 12.5 0.0 7.5 8 0 0 8 8 8 3 KH domain KH_5 PF13184.6 CAR30439.1 - 2.6e-07 30.6 13.9 0.05 13.7 0.0 7.3 6 1 1 7 7 7 3 NusA-like KH domain YscW PF09619.10 CAR30439.1 - 0.016 15.5 0.0 2.1 8.8 0.0 3.4 3 0 0 3 3 3 0 Type III secretion system lipoprotein chaperone (YscW) CAP PF00188.26 CAR30440.1 - 1.6e-17 64.5 5.1 2.5e-17 63.9 5.1 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Med25_NR-box PF11244.8 CAR30440.1 - 0.057 13.8 0.1 0.092 13.2 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing CAP PF00188.26 CAR30441.1 - 7.3e-20 72.1 1.8 7.3e-20 72.1 1.8 2.6 2 1 0 2 2 2 1 Cysteine-rich secretory protein family MAJIN PF15077.6 CAR30441.1 - 0.44 10.3 4.7 0.72 9.6 4.7 1.3 1 0 0 1 1 1 0 Membrane-anchored junction protein Utp14 PF04615.13 CAR30441.1 - 6.7 5.2 17.5 7.9 4.9 17.5 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 CAR30441.1 - 8 4.9 25.4 12 4.3 25.4 1.3 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 CAR30442.1 - 2.3e-31 109.0 40.5 2.3e-31 109.0 40.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR30442.1 - 7.9e-09 34.5 1.6 1.3e-08 33.8 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_7 PF03441.14 CAR30444.1 - 3.2e-70 235.7 0.4 6.5e-70 234.7 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CAR30444.1 - 2.2e-30 105.8 1.5 4.9e-30 104.7 1.5 1.6 1 0 0 1 1 1 1 DNA photolyase Cytokin_check_N PF10407.9 CAR30445.1 - 3e-29 100.8 1.1 6e-29 99.8 1.1 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SMC_N PF02463.19 CAR30446.1 - 4.3e-57 193.1 29.9 2.9e-56 190.3 29.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR30446.1 - 8.5e-27 93.8 0.0 3.5e-26 91.8 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CAR30446.1 - 2.3e-17 64.1 0.4 2.3e-17 64.1 0.4 7.1 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 CAR30446.1 - 1.2e-10 41.7 28.3 5.1e-06 26.5 9.5 4.6 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CAR30446.1 - 7.1e-09 35.8 69.8 5.3e-07 29.7 26.3 4.8 1 1 1 3 3 3 1 AAA ATPase domain CENP-F_leu_zip PF10473.9 CAR30446.1 - 0.00081 19.4 5.6 0.00081 19.4 5.6 7.5 3 2 5 8 8 8 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.6 CAR30446.1 - 0.031 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mem_trans PF03547.18 CAR30447.1 - 8.2e-61 205.5 11.0 2.1e-59 200.9 11.0 2.0 1 1 0 1 1 1 1 Membrane transport protein DnaJ PF00226.31 CAR30448.1 - 2.1e-20 72.6 2.0 6.9e-20 70.9 2.0 2.0 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 CAR30448.1 - 0.14 12.2 25.6 0.28 11.1 25.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M28 PF04389.17 CAR30449.1 - 4.5e-40 137.5 0.1 6.1e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CAR30449.1 - 6.2e-11 42.2 0.0 1.6e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CAR30449.1 - 7.5e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CAR30449.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Sld5 PF05916.11 CAR30451.1 - 4.5e-19 68.9 0.5 7.6e-19 68.2 0.5 1.4 1 0 0 1 1 1 1 GINS complex protein NAT PF04768.13 CAR30452.1 - 2.4e-48 164.0 0.4 6.5e-48 162.6 0.0 1.9 3 0 0 3 3 3 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase KHA PF11834.8 CAR30452.1 - 0.011 15.8 2.5 0.037 14.1 0.5 2.4 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Methyltr_RsmB-F PF01189.17 CAR30452.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F A_deaminase PF00962.22 CAR30453.1 - 2.3e-20 73.2 0.0 6.2e-08 32.3 0.0 3.8 3 1 0 3 3 3 3 Adenosine/AMP deaminase SHMT PF00464.19 CAR30454.1 - 4.5e-202 670.9 0.0 5.4e-202 670.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Ras PF00071.22 CAR30455.1 - 3.1e-40 137.4 0.4 2.3e-39 134.6 0.4 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CAR30455.1 - 3.2e-32 111.3 0.6 4.1e-32 110.9 0.6 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR30455.1 - 5.4e-17 61.8 0.2 1.2e-16 60.7 0.2 1.4 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR30455.1 - 2.2e-07 31.0 0.1 3.6e-07 30.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR30455.1 - 1.1e-05 25.0 0.2 0.0023 17.5 0.2 2.6 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAR30455.1 - 3.3e-05 23.4 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CAR30455.1 - 0.00035 20.0 0.0 0.00043 19.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CAR30455.1 - 0.013 15.9 0.1 0.017 15.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 CAR30455.1 - 0.058 12.5 1.8 3.8 6.6 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 CAR30455.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein RsgA_GTPase PF03193.16 CAR30455.1 - 0.094 12.6 0.4 0.83 9.5 0.2 2.2 1 1 0 2 2 2 0 RsgA GTPase DAP3 PF10236.9 CAR30455.1 - 0.11 11.7 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 CAR30455.1 - 0.14 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Rif1_N PF12231.8 CAR30456.1 - 6.2e-31 107.7 12.1 1.4e-30 106.6 12.1 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Sec7_N PF12783.7 CAR30456.1 - 0.19 11.6 0.1 0.19 11.6 0.1 4.6 5 0 0 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.25 CAR30457.1 - 2e-60 204.4 0.0 2.5e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30457.1 - 3.8e-33 114.9 0.0 5.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR30457.1 - 2.2e-07 30.0 0.0 3.3e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CAR30457.1 - 5e-07 29.3 0.0 2.4e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CAR30457.1 - 0.029 13.4 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CAR30457.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CAR30457.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAR30457.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CAR30457.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR30457.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UBX PF00789.20 CAR30458.1 - 7.5e-18 64.5 0.0 1.9e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 UBX domain LPD34 PF18852.1 CAR30458.1 - 0.0086 15.7 1.1 0.015 14.9 1.1 1.3 1 0 0 1 1 1 1 Large polyvalent protein associated domain 34 DUF4160 PF13711.6 CAR30458.1 - 0.15 12.4 2.4 23 5.4 1.9 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4160) Snf7 PF03357.21 CAR30459.1 - 5.4e-11 42.4 16.7 8.1e-11 41.8 16.7 1.2 1 0 0 1 1 1 1 Snf7 End3 PF12761.7 CAR30459.1 - 0.088 13.0 10.6 1.5 8.9 0.0 2.9 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 MMACHC PF16690.5 CAR30459.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family DNA_topoisoIV PF00521.20 CAR30459.1 - 1.8 7.4 9.9 1.4 7.8 8.0 1.4 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A FapA PF03961.13 CAR30459.1 - 4.1 5.9 13.2 0.072 11.7 2.6 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A HSM3_N PF18795.1 CAR30460.1 - 2.6e-60 203.8 4.1 3.9e-60 203.2 4.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain HSM3_C PF18794.1 CAR30460.1 - 5e-53 179.3 1.4 1e-52 178.3 1.4 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, C terminal domain E3_UbLigase_R4 PF13764.6 CAR30460.1 - 0.0031 15.8 0.2 0.0043 15.3 0.2 1.1 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 BLYB PF05289.11 CAR30460.1 - 0.35 11.1 0.0 0.35 11.1 0.0 2.8 4 0 0 4 4 4 0 Borrelia hemolysin accessory protein rRNA_proc-arch PF13234.6 CAR30461.1 - 1.5e-75 254.6 2.4 1.5e-75 254.6 2.4 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CAR30461.1 - 4.1e-55 185.9 0.6 1.1e-54 184.5 0.6 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CAR30461.1 - 4.9e-19 68.8 0.0 2.2e-17 63.4 0.0 2.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30461.1 - 1.4e-06 28.6 0.0 1.1e-05 25.7 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CAR30461.1 - 0.13 12.5 0.0 0.48 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Vps26 PF03643.15 CAR30463.1 - 6.3e-111 369.8 0.0 7.3e-111 369.6 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CAR30463.1 - 1.3e-05 25.3 0.5 0.0059 16.7 0.4 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CAR30463.1 - 0.0036 17.7 0.2 0.017 15.6 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 CAR30463.1 - 0.02 14.1 0.3 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 Rgp1 Tim54 PF11711.8 CAR30464.1 - 6.2e-135 449.8 1.4 8e-135 449.4 1.4 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 AAR2 PF05282.11 CAR30464.1 - 0.074 12.4 2.7 0.47 9.8 2.7 1.9 1 1 0 1 1 1 0 AAR2 protein Myb_DNA-binding PF00249.31 CAR30465.1 - 2.9e-22 78.6 0.3 8.4e-13 48.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR30465.1 - 1.3e-17 63.8 0.9 2.6e-14 53.2 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 CAR30465.1 - 0.049 13.6 0.0 0.085 12.9 0.0 1.4 1 0 0 1 1 1 0 SLIDE Death PF00531.22 CAR30465.1 - 0.2 11.8 0.4 3.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Death domain Lysine_decarbox PF03641.14 CAR30466.1 - 3.2e-44 150.2 0.1 4.5e-44 149.7 0.1 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CAR30466.1 - 2.8e-11 43.2 0.1 1.2e-10 41.2 0.1 1.9 1 1 0 1 1 1 1 SLOG cluster4 family zf-BED PF02892.15 CAR30466.1 - 0.021 14.8 0.3 0.28 11.2 0.1 2.2 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 CAR30467.1 - 1.1e-24 85.4 59.9 2.4e-06 27.7 1.4 9.4 9 0 0 9 9 8 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR30467.1 - 4.5e-20 71.1 53.1 1.9e-08 34.3 0.3 7.8 9 0 0 9 9 7 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CAR30467.1 - 2e-13 50.2 17.6 0.00021 21.5 0.8 5.9 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CAR30467.1 - 2.8e-13 49.5 68.4 0.00016 22.3 0.7 9.7 10 0 0 10 10 8 6 C2H2-type zinc finger Zap1_zf2 PF18217.1 CAR30467.1 - 2.5e-12 46.5 6.7 2.5e-12 46.5 6.7 4.4 4 0 0 4 4 4 1 Zap1 zinc finger 2 zf-C2HC_2 PF13913.6 CAR30467.1 - 2.4e-07 30.5 14.1 0.019 14.8 1.0 4.8 4 0 0 4 4 4 3 zinc-finger of a C2HC-type FOXP-CC PF16159.5 CAR30467.1 - 1e-05 26.0 40.2 0.0074 16.9 0.6 7.6 5 1 2 7 7 7 4 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CAR30467.1 - 0.00012 22.0 29.2 0.00079 19.4 1.9 5.7 4 1 1 5 5 5 2 C2H2-type zinc finger zf-met PF12874.7 CAR30467.1 - 0.021 15.2 19.9 0.31 11.5 0.7 5.3 5 0 0 5 5 4 0 Zinc-finger of C2H2 type Spt46 PF17734.1 CAR30467.1 - 0.023 14.5 1.7 0.023 14.5 1.7 2.5 2 1 1 3 3 3 0 Spermatogenesis-associated protein 46 zf-C2H2_11 PF16622.5 CAR30467.1 - 0.069 12.9 0.4 0.069 12.9 0.4 5.4 6 0 0 6 6 5 0 zinc-finger C2H2-type Nif11 PF07862.11 CAR30467.1 - 0.074 13.4 0.0 17 5.8 0.0 2.7 2 0 0 2 2 2 0 Nif11 domain Phage_Orf51 PF06194.11 CAR30467.1 - 0.83 9.7 3.5 98 3.1 2.6 3.7 5 0 0 5 5 4 0 Phage Conserved Open Reading Frame 51 DUF2225 PF09986.9 CAR30467.1 - 1.4 8.6 11.2 1.2 8.8 1.7 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_9 PF16293.5 CAR30467.1 - 1.6 8.6 11.3 1.1 9.2 0.1 4.4 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) Zn_ribbon_SprT PF17283.2 CAR30467.1 - 2 8.4 15.4 0.74 9.8 0.9 4.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Methyltransf_16 PF10294.9 CAR30468.1 - 3.6e-22 78.9 0.0 5.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CAR30468.1 - 1.1e-07 31.8 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR30468.1 - 0.0025 17.6 0.0 0.0055 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR30468.1 - 0.004 17.9 0.0 0.008 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 CAR30468.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 CAR30469.1 - 4.2e-32 111.6 0.0 4.5e-31 108.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30469.1 - 8.4e-20 71.1 0.0 5.5e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR30469.1 - 4.7e-05 22.3 0.0 7.1e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M41 PF01434.18 CAR30469.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M41 Kdo PF06293.14 CAR30469.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CAR30469.1 - 0.14 11.8 0.0 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HbrB PF08539.11 CAR30470.1 - 8e-37 126.8 0.5 8e-37 126.8 0.5 1.8 2 0 0 2 2 2 1 HbrB-like CLN3 PF02487.17 CAR30471.1 - 1.8e-145 485.0 11.6 2.6e-145 484.4 11.6 1.2 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CAR30471.1 - 0.0012 17.8 4.2 0.0012 17.8 4.2 2.9 1 1 0 2 2 2 1 Major Facilitator Superfamily PrgI PF12666.7 CAR30471.1 - 0.18 12.5 0.1 0.18 12.5 0.1 3.1 3 1 0 3 3 3 0 PrgI family protein Aminotran_1_2 PF00155.21 CAR30472.1 - 5.7e-80 269.2 0.0 6.8e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CAR30472.1 - 0.0013 17.7 0.0 0.0035 16.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CAR30472.1 - 0.0082 15.5 0.0 0.02 14.2 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CAR30472.1 - 0.011 14.3 0.0 0.023 13.2 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1674 PF07896.12 CAR30473.1 - 7.8e-17 61.5 5.2 8.4e-17 61.4 3.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1674) Nup88 PF10168.9 CAR30474.1 - 1.6e-05 22.9 16.0 0.012 13.4 15.1 2.2 2 0 0 2 2 2 2 Nuclear pore component Sec34 PF04136.15 CAR30474.1 - 0.041 13.8 3.9 0.14 12.0 3.9 1.9 1 0 0 1 1 1 0 Sec34-like family Ribosomal_L37 PF08561.10 CAR30475.1 - 5.7e-24 84.9 6.6 7.2e-19 68.5 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 CcmD PF04995.14 CAR30475.1 - 0.61 10.2 1.8 0.71 10.0 0.1 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Phosphodiest PF01663.22 CAR30476.1 - 2.1e-14 53.9 0.8 9.6e-09 35.3 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CAR30476.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Metalloenzyme superfamily Fe-S_biosyn PF01521.20 CAR30476.1 - 0.013 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Iron-sulphur cluster biosynthesis Sulfatase PF00884.23 CAR30476.1 - 0.042 13.2 0.0 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 Sulfatase zf-C2H2_2 PF12756.7 CAR30477.1 - 3e-35 120.6 0.7 5.2e-32 110.2 0.2 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) PP_kinase_C PF13090.6 CAR30477.1 - 0.057 12.9 0.1 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 Peptidase_C98 PF15499.6 CAR30477.1 - 0.087 12.3 1.2 0.18 11.2 1.2 1.5 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-C2H2 PF00096.26 CAR30477.1 - 0.15 12.6 7.7 1.6 9.3 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Presenilin PF01080.17 CAR30477.1 - 0.27 9.9 2.3 0.42 9.3 2.3 1.3 1 0 0 1 1 1 0 Presenilin zf-C2H2_4 PF13894.6 CAR30477.1 - 0.47 11.4 4.3 4.1 8.5 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger adh_short PF00106.25 CAR30478.1 - 7e-21 74.6 0.0 2.6e-18 66.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR30478.1 - 7.9e-13 48.7 0.0 1.2e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CAR30478.1 - 5e-07 29.5 0.0 3.2e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Mrpl_C PF18502.1 CAR30480.1 - 2.8e-40 137.1 1.2 6.6e-40 135.9 1.0 1.7 2 0 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain Ribosomal_L17 PF01196.19 CAR30480.1 - 2.3e-28 98.9 0.1 5.8e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L17 PALP PF00291.25 CAR30481.1 - 2.8e-63 214.1 0.0 3.2e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.20 CAR30482.1 - 1.9e-25 89.2 0.7 1.1e-21 77.0 0.3 3.5 3 1 0 4 4 4 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR30482.1 - 6.2e-06 26.0 0.2 2.2e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CAR30482.1 - 0.041 14.2 0.2 0.1 12.9 0.2 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 CAR30482.1 - 0.06 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate CBFD_NFYB_HMF PF00808.23 CAR30483.1 - 1.6e-05 25.1 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trypan_PARP PF05887.11 CAR30483.1 - 0.37 10.8 10.7 0.74 9.8 10.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MPM1 PF17234.2 CAR30484.1 - 1.7e-52 178.1 1.2 2.6e-52 177.5 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 Viral_NABP PF05515.11 CAR30484.1 - 0.02 14.8 0.0 5.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Viral nucleic acid binding Paf1 PF03985.13 CAR30485.1 - 3.1e-96 323.0 13.6 3.4e-96 322.8 13.6 1.0 1 0 0 1 1 1 1 Paf1 Esterase PF00756.20 CAR30486.1 - 2.3e-56 191.2 0.1 2.6e-56 191.1 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CAR30486.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CAR30486.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 CAR30486.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CAR30486.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.18 CAR30486.1 - 0.14 11.7 0.1 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 CAR30486.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme RCC1_2 PF13540.6 CAR30487.1 - 6.7e-17 60.8 16.3 2.8e-09 36.6 0.2 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CAR30487.1 - 5.7e-13 49.3 5.4 0.0018 18.9 0.1 7.2 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 CAR30487.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR30487.1 - 0.05 13.5 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 F-box domain Peptidase_M20 PF01546.28 CAR30488.1 - 6.5e-22 78.3 0.0 1.4e-21 77.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR30488.1 - 4.9e-12 45.7 0.0 8.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 CAR30488.1 - 1.2e-08 35.4 5.0 0.051 14.5 0.0 5.8 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30488.1 - 0.021 15.1 0.0 12 6.3 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SIMPL PF04402.14 CAR30488.1 - 0.13 12.7 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) WD40 PF00400.32 CAR30489.1 - 9.5e-16 57.9 0.0 0.0004 21.1 0.0 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30489.1 - 2.5e-10 40.5 0.0 0.0029 17.9 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 CAR30489.1 - 0.045 12.8 0.1 0.58 9.1 0.0 2.4 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain DUF5449 PF17528.2 CAR30489.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5449) MRP-L27 PF09809.9 CAR30490.1 - 5.3e-34 116.4 1.3 8e-34 115.9 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.20 CAR30491.1 - 1.2e-43 149.5 13.3 1.8e-43 149.0 13.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CAR30491.1 - 2.7e-10 39.9 0.2 2.7e-10 39.9 0.2 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p AIM5 PF17050.5 CAR30492.1 - 1.8e-06 28.7 0.0 1.9e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 HRI1 PF16815.5 CAR30492.1 - 0.0043 16.8 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein HRI1 WAPL PF07814.13 CAR30492.1 - 0.074 11.8 0.0 0.074 11.8 0.0 1.0 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Methyltransf_PK PF05891.12 CAR30493.1 - 6.5e-93 310.3 0.0 7.3e-93 310.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 CAR30493.1 - 2.7e-06 27.3 0.0 4.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR30493.1 - 5.8e-05 23.7 0.0 0.00011 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR30493.1 - 0.013 16.2 0.0 0.06 14.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 CAR30493.1 - 0.057 12.7 0.1 0.12 11.6 0.1 1.4 1 1 0 1 1 1 0 O-methyltransferase domain RhoGAP PF00620.27 CAR30494.1 - 2.4e-37 128.1 0.0 1.1e-36 126.0 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CAR30494.1 - 2.9e-07 30.7 0.4 2.9e-07 30.7 0.4 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain MarR_2 PF12802.7 CAR30495.1 - 0.14 12.1 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 MarR family COMPASS-Shg1 PF05205.12 CAR30497.1 - 1.8e-23 83.2 0.6 2.2e-23 82.9 0.6 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 UPF0086 PF01868.16 CAR30498.1 - 5.2e-22 77.6 0.0 1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 BPL_LplA_LipB PF03099.19 CAR30499.1 - 7.5e-08 32.4 0.1 3.1e-07 30.4 0.1 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PriCT_1 PF08708.11 CAR30499.1 - 0.064 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) WD40 PF00400.32 CAR30500.1 - 0.00017 22.3 0.4 11 7.1 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PI-PLC-X PF00388.19 CAR30501.1 - 5.9e-11 42.2 0.0 1.2e-10 41.1 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain WHIM1 PF15612.6 CAR30502.1 - 1.6e-08 33.8 0.1 3.9e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 NOA36 PF06524.12 CAR30502.1 - 4.6 6.5 15.5 8.5 5.6 15.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 CAR30503.1 - 3.1e-73 246.4 0.0 4.4e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30503.1 - 1.2e-39 136.2 0.0 2.1e-39 135.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR30503.1 - 3.8e-07 29.7 0.0 6.8e-06 25.6 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAR30503.1 - 1.4e-05 24.1 0.1 0.00013 20.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CAR30503.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 CAR30503.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 ABC1 family TMF_DNA_bd PF12329.8 CAR30503.1 - 0.89 9.6 4.7 7.3 6.7 0.4 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Glycogen_syn PF05693.13 CAR30504.1 - 0 1091.7 0.0 0 1091.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CAR30504.1 - 1.1e-07 31.6 0.0 1.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAR30504.1 - 5.2e-06 26.9 0.0 0.0034 17.8 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR30504.1 - 1.7e-05 24.9 0.2 7.3e-05 22.8 0.1 2.0 1 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 CAR30504.1 - 4e-05 23.4 0.2 9.2e-05 22.3 0.2 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 CAR30504.1 - 7.1e-05 23.3 0.1 0.00017 22.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Phage_hub_GP28 PF11110.8 CAR30504.1 - 0.11 12.4 0.2 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 Baseplate hub distal subunit SH3BGR PF04908.15 CAR30507.1 - 0.012 15.8 0.0 0.039 14.1 0.0 1.9 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein NpwBP PF12622.7 CAR30507.1 - 0.1 13.4 0.2 0.1 13.4 0.2 3.5 3 0 0 3 3 3 0 mRNA biogenesis factor baeRF_family6 PF18848.1 CAR30508.1 - 0.0031 17.9 0.3 0.0075 16.7 0.3 1.7 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 6 baeRF_family7 PF18849.1 CAR30508.1 - 0.05 13.8 0.4 0.096 12.9 0.4 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 Ferric_reduct PF01794.19 CAR30509.1 - 2e-20 73.2 11.1 2e-20 73.2 11.1 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CAR30509.1 - 4.7e-17 62.5 0.0 6.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CAR30509.1 - 5e-10 39.4 0.0 9.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Peptidase_A24 PF01478.18 CAR30509.1 - 0.88 10.0 7.4 0.17 12.3 2.6 2.4 2 1 0 2 2 2 0 Type IV leader peptidase family Fungal_trans PF04082.18 CAR30510.1 - 1.3e-11 44.1 2.8 3.5e-11 42.6 2.8 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR30510.1 - 2.2e-08 34.1 9.2 5e-08 32.9 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_27 PF13463.6 CAR30510.1 - 0.036 14.6 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain OCD_Mu_crystall PF02423.15 CAR30511.1 - 5.5e-15 55.1 0.0 1.2e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Leu_zip PF15294.6 CAR30512.1 - 0.00019 21.1 8.1 0.00025 20.7 0.6 2.0 1 1 1 2 2 2 1 Leucine zipper Angiomotin_C PF12240.8 CAR30512.1 - 0.00056 19.5 0.9 0.00056 19.5 0.9 2.4 2 1 1 3 3 2 1 Angiomotin C terminal BLOC1_2 PF10046.9 CAR30512.1 - 0.0078 16.5 8.6 0.14 12.5 2.8 2.6 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fungal_TACC PF12709.7 CAR30512.1 - 0.0085 16.5 7.4 0.061 13.8 1.7 2.3 2 0 0 2 2 2 1 Fungal Transforming acidic coiled-coil (TACC) proteins APG6_N PF17675.1 CAR30512.1 - 0.0098 16.4 13.7 0.16 12.5 13.9 2.1 1 1 0 1 1 1 1 Apg6 coiled-coil region CEP63 PF17045.5 CAR30512.1 - 0.01 15.8 8.1 0.47 10.3 8.1 2.1 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa bZIP_1 PF00170.21 CAR30512.1 - 0.012 15.7 11.6 0.013 15.6 1.9 2.5 2 0 0 2 2 2 0 bZIP transcription factor GAS PF13851.6 CAR30512.1 - 0.017 14.5 8.4 0.043 13.2 8.5 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding vATP-synt_E PF01991.18 CAR30512.1 - 0.02 14.3 5.0 0.4 10.1 0.7 2.2 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Fez1 PF06818.15 CAR30512.1 - 0.031 14.7 5.7 0.057 13.9 5.6 1.6 1 1 0 1 1 1 0 Fez1 Fzo_mitofusin PF04799.13 CAR30512.1 - 0.036 13.6 1.7 0.069 12.7 1.4 1.6 1 1 0 1 1 1 0 fzo-like conserved region HIP1_clath_bdg PF16515.5 CAR30512.1 - 0.038 14.6 5.5 0.06 14.0 4.9 1.6 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5365 PF17326.2 CAR30512.1 - 0.066 13.6 0.5 0.13 12.7 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5365) YabA PF06156.13 CAR30512.1 - 0.07 13.8 7.9 0.21 12.3 0.7 2.5 1 1 1 2 2 2 0 Initiation control protein YabA PriX PF18689.1 CAR30512.1 - 0.12 12.7 0.1 0.24 11.8 0.1 1.5 1 0 0 1 1 1 0 Primase X CCDC106 PF15794.5 CAR30512.1 - 0.13 11.9 9.0 0.028 14.1 2.4 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 106 ZapB PF06005.12 CAR30512.1 - 0.15 12.5 14.2 2.3 8.7 3.7 2.7 2 1 0 2 2 2 0 Cell division protein ZapB CCDC-167 PF15188.6 CAR30512.1 - 0.16 12.3 4.7 0.33 11.3 4.7 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 NYD-SP28 PF14772.6 CAR30512.1 - 0.2 11.7 6.4 0.08 13.0 2.6 2.0 2 0 0 2 2 2 0 Sperm tail DUF4407 PF14362.6 CAR30512.1 - 0.21 10.9 2.6 0.61 9.4 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 CAR30512.1 - 0.25 11.4 8.9 1.1 9.3 0.5 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Filament PF00038.21 CAR30512.1 - 0.25 10.9 9.7 1.2 8.6 2.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein Swi5 PF07061.11 CAR30512.1 - 0.28 11.3 8.4 1.2 9.2 2.4 2.5 2 0 0 2 2 2 0 Swi5 Tropomyosin PF00261.20 CAR30512.1 - 0.3 10.4 9.9 0.63 9.4 0.9 2.1 1 1 1 2 2 2 0 Tropomyosin TSC22 PF01166.18 CAR30512.1 - 0.31 11.4 10.1 3.6 8.0 0.7 3.0 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF1664 PF07889.12 CAR30512.1 - 0.31 11.1 4.7 0.43 10.6 1.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 CAR30512.1 - 0.32 11.2 9.2 0.56 10.4 1.6 3.0 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 CAR30512.1 - 0.34 11.1 9.9 10 6.4 10.0 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CAR30512.1 - 0.34 10.9 10.5 1.3 9.1 1.4 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding YscO PF07321.12 CAR30512.1 - 0.36 10.8 8.1 0.6 10.1 6.9 1.9 1 1 1 2 2 2 0 Type III secretion protein YscO SIKE PF05769.11 CAR30512.1 - 0.44 10.5 7.9 2.1 8.3 2.4 2.4 1 1 1 2 2 2 0 SIKE family CENP-F_leu_zip PF10473.9 CAR30512.1 - 0.44 10.6 12.0 2 8.4 12.0 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACCA PF03255.14 CAR30512.1 - 0.49 10.3 3.8 0.33 10.8 1.6 1.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Phage_GP20 PF06810.11 CAR30512.1 - 0.51 10.1 6.8 1.3 8.8 2.2 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 TolA_bind_tri PF16331.5 CAR30512.1 - 0.65 10.1 10.4 2.6 8.2 1.0 2.7 2 1 0 2 2 2 0 TolA binding protein trimerisation Csm1_N PF18504.1 CAR30512.1 - 0.72 10.2 10.2 2.1 8.8 0.5 3.2 2 1 1 3 3 3 0 Csm1 N-terminal domain ADIP PF11559.8 CAR30512.1 - 0.83 9.7 8.5 7.8 6.6 2.0 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exonuc_VII_S PF02609.16 CAR30512.1 - 1.1 9.4 10.8 23 5.2 0.3 3.7 2 1 0 3 3 3 0 Exonuclease VII small subunit HSCB_C PF07743.13 CAR30512.1 - 1.4 9.5 8.6 0.22 12.1 2.1 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain XhlA PF10779.9 CAR30512.1 - 1.4 9.1 4.8 21 5.4 0.2 2.6 2 1 0 2 2 2 0 Haemolysin XhlA DUF641 PF04859.12 CAR30512.1 - 1.9 8.8 6.6 1.1 9.6 1.5 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 CAR30512.1 - 2.2 8.2 0.0 2.2 8.2 0.0 3.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_MLP1_2 PF07926.12 CAR30512.1 - 2.3 8.3 15.6 1.2 9.2 11.9 2.4 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CAR30512.1 - 2.7 6.8 11.6 8.8 5.1 1.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 CAR30512.1 - 3 8.3 10.3 13 6.3 1.3 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) TEX13 PF15186.6 CAR30512.1 - 3.1 7.5 8.9 12 5.6 1.9 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family BST2 PF16716.5 CAR30512.1 - 3.9 8.1 9.6 1.3 9.7 2.3 2.8 1 1 2 3 3 2 0 Bone marrow stromal antigen 2 FlaC_arch PF05377.11 CAR30512.1 - 5.2 7.5 8.9 15 6.1 0.7 3.2 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 CAR30512.1 - 5.7 7.2 9.6 2.1 8.6 1.6 2.7 1 1 0 2 2 2 0 JNK-interacting protein leucine zipper II UPF0242 PF06785.11 CAR30512.1 - 8.9 6.4 12.0 8.1 6.5 5.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ABC1 PF03109.16 CAR30513.1 - 9.1e-34 116.2 0.0 2.4e-33 114.8 0.0 1.8 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CAR30513.1 - 9.6e-05 22.1 0.0 0.001 18.7 0.0 2.6 3 0 0 3 3 3 1 RIO1 family Mpv17_PMP22 PF04117.12 CAR30514.1 - 3.8e-25 87.9 3.5 6.8e-25 87.1 3.5 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Zn_clus PF00172.18 CAR30516.1 - 1.2e-06 28.5 10.7 1.2e-06 28.5 10.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR30516.1 - 6.7e-06 25.3 0.0 2.2e-05 23.6 0.0 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain TP_methylase PF00590.20 CAR30518.1 - 2.7e-28 99.4 0.0 4e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.6 CAR30518.1 - 0.077 13.0 0.1 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) Clat_adaptor_s PF01217.20 CAR30519.1 - 3.5e-53 179.4 3.4 4e-53 179.2 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 CAR30521.1 - 5e-60 203.1 0.0 8.6e-60 202.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30521.1 - 4e-25 88.6 0.0 8.9e-25 87.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAR30521.1 - 0.0002 20.8 0.0 0.00046 19.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAR30521.1 - 0.00037 19.9 0.1 0.42 9.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 CAR30521.1 - 0.0011 18.6 0.2 0.02 14.5 0.0 2.3 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAR30521.1 - 0.075 12.9 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PilN_bio_d PF18222.1 CAR30521.1 - 0.13 12.7 0.2 0.31 11.4 0.2 1.6 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain ABC_tran PF00005.27 CAR30523.1 - 1.1e-45 155.5 0.0 3e-23 82.8 0.0 4.3 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 CAR30523.1 - 4e-27 94.1 0.5 1.5e-26 92.3 0.1 2.3 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 CAR30523.1 - 4.8e-18 66.0 1.4 0.0038 17.1 0.0 5.3 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR30523.1 - 4.6e-16 58.9 0.1 2.6e-06 27.1 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR30523.1 - 2.8e-10 41.1 4.2 0.0011 19.5 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 CAR30523.1 - 1.2e-08 34.6 0.0 0.0045 16.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR30523.1 - 1.2e-08 35.0 0.0 0.00027 20.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CAR30523.1 - 6.5e-08 32.9 0.0 0.013 15.8 0.0 4.2 4 1 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.23 CAR30523.1 - 2.1e-07 31.0 0.0 0.0021 18.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 CAR30523.1 - 4.2e-07 30.3 0.1 0.011 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 CAR30523.1 - 1.2e-06 28.7 0.6 3.3e-05 24.0 0.0 3.0 3 0 0 3 3 2 1 Dynamin family MMS19_C PF12460.8 CAR30523.1 - 2.3e-06 27.0 2.5 0.022 13.9 0.0 3.2 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal AAA PF00004.29 CAR30523.1 - 4.1e-06 27.3 0.3 0.7 10.3 0.0 4.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CAR30523.1 - 7.4e-06 25.1 0.1 0.12 11.4 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CAR30523.1 - 1.2e-05 25.6 0.0 0.13 12.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase CLASP_N PF12348.8 CAR30523.1 - 1.2e-05 24.9 2.8 0.004 16.7 0.5 2.8 1 1 1 2 2 2 1 CLASP N terminal AAA_33 PF13671.6 CAR30523.1 - 5.4e-05 23.4 0.0 0.58 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAR30523.1 - 8.5e-05 23.0 1.0 0.22 11.9 0.0 3.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 CAR30523.1 - 9e-05 23.0 0.0 0.92 10.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 CAR30523.1 - 0.00022 20.9 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ParcG PF10274.9 CAR30523.1 - 0.00034 20.8 1.2 0.28 11.3 0.0 2.8 2 1 1 3 3 3 1 Parkin co-regulated protein DUF87 PF01935.17 CAR30523.1 - 0.00049 20.3 1.8 0.43 10.6 0.0 4.2 4 0 0 4 4 3 1 Helicase HerA, central domain AAA_30 PF13604.6 CAR30523.1 - 0.0011 18.7 0.1 2.7 7.7 0.0 3.5 4 0 0 4 4 3 1 AAA domain PduV-EutP PF10662.9 CAR30523.1 - 0.0014 18.4 0.0 0.21 11.3 0.0 3.2 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 CAR30523.1 - 0.0015 18.7 0.1 0.61 10.4 0.0 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 CAR30523.1 - 0.0019 18.0 0.1 1.5 8.5 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 CAR30523.1 - 0.0019 17.9 6.1 0.54 9.9 0.0 3.9 5 0 0 5 5 2 2 AAA ATPase domain NACHT PF05729.12 CAR30523.1 - 0.0024 17.8 0.0 1.2 9.0 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Rad17 PF03215.15 CAR30523.1 - 0.0026 17.7 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain cobW PF02492.19 CAR30523.1 - 0.0062 16.1 0.0 4 7.0 0.0 3.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 CAR30523.1 - 0.011 15.8 0.0 7.9 6.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 CAR30523.1 - 0.017 14.9 0.1 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_13 PF13166.6 CAR30523.1 - 0.017 13.8 4.8 2.9 6.4 0.0 3.9 4 0 0 4 4 4 0 AAA domain Roc PF08477.13 CAR30523.1 - 0.019 15.2 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 CAR30523.1 - 0.019 14.9 0.1 14 5.5 0.0 3.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea CLP1_P PF16575.5 CAR30523.1 - 0.021 14.6 0.1 2.5 7.9 0.0 3.0 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HEAT_2 PF13646.6 CAR30523.1 - 0.026 14.9 6.3 2.8 8.4 0.1 3.6 2 1 1 3 3 3 0 HEAT repeats IstB_IS21 PF01695.17 CAR30523.1 - 0.029 14.1 0.0 7.8 6.2 0.0 3.1 3 0 0 3 3 2 0 IstB-like ATP binding protein G-alpha PF00503.20 CAR30523.1 - 0.033 13.3 0.0 4.8 6.2 0.0 2.5 2 0 0 2 2 2 0 G-protein alpha subunit Mg_chelatase PF01078.21 CAR30523.1 - 0.034 13.5 0.4 1.4 8.2 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 CAR30523.1 - 0.038 13.0 0.0 0.64 9.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein MutS_V PF00488.21 CAR30523.1 - 0.041 13.9 0.1 6.4 6.8 0.1 2.6 2 0 0 2 2 2 0 MutS domain V NTPase_1 PF03266.15 CAR30523.1 - 0.044 13.7 0.1 14 5.6 0.1 2.8 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 CAR30523.1 - 0.047 13.5 0.2 8 6.2 0.1 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CAR30523.1 - 0.047 13.2 0.0 6.9 6.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 CAR30523.1 - 0.055 13.4 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Adaptin_N PF01602.20 CAR30523.1 - 0.081 11.5 7.9 0.86 8.1 8.1 2.3 1 1 0 1 1 1 0 Adaptin N terminal region TsaE PF02367.17 CAR30523.1 - 0.091 12.8 0.1 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 CAR30523.1 - 0.1 11.9 0.4 2.7 7.2 0.0 2.6 3 0 0 3 3 2 0 Septin MukB PF04310.12 CAR30523.1 - 0.12 12.2 0.2 14 5.4 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal HEAT PF02985.22 CAR30523.1 - 0.14 12.5 2.2 30 5.2 0.0 4.3 5 0 0 5 5 2 0 HEAT repeat Vac14_Fab1_bd PF12755.7 CAR30523.1 - 0.17 12.5 0.2 12 6.6 0.0 3.1 3 0 0 3 3 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CAR30523.1 - 0.35 11.4 6.5 1.9 9.1 0.1 4.2 4 0 0 4 4 3 0 HEAT-like repeat Ac76 PF05814.11 CAR30523.1 - 6 6.9 6.4 53 3.9 0.0 3.3 3 0 0 3 3 3 0 Orf76 (Ac76) PIN_12 PF16289.5 CAR30523.1 - 8.7 6.8 7.2 2.7 8.5 0.0 3.3 3 0 0 3 3 3 0 PIN domain PLA2_B PF01735.18 CAR30524.1 - 3.3e-92 309.4 2.9 8.2e-77 258.7 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 CAR30524.1 - 0.00011 22.5 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase PHA_synth_III_E PF09712.10 CAR30524.1 - 0.055 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) EF-hand_7 PF13499.6 CAR30525.1 - 0.00033 21.0 2.5 0.00033 21.0 2.5 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CAR30525.1 - 0.0039 17.0 2.3 1.8 8.7 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CAR30525.1 - 0.037 13.6 3.0 0.21 11.2 0.4 2.7 2 0 0 2 2 2 0 EF hand Flavodoxin_1 PF00258.25 CAR30525.1 - 0.054 13.7 0.4 0.097 12.9 0.0 1.7 2 0 0 2 2 2 0 Flavodoxin UPF0052 PF01933.18 CAR30526.1 - 8.2e-60 202.5 0.0 1.1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 HAD PF12710.7 CAR30527.1 - 2.9e-27 96.3 0.0 3.6e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CAR30527.1 - 1.1e-06 28.3 0.0 1.1e-05 25.1 0.0 2.2 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 CAR30527.1 - 3.2e-06 26.7 0.0 4.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.26 CAR30527.1 - 7.4e-06 26.4 0.0 0.00019 21.8 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Iso_dh PF00180.20 CAR30528.1 - 8.2e-74 248.8 0.0 9.4e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase UEV PF05743.13 CAR30529.1 - 1.7e-22 79.5 0.0 3.1e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CAR30529.1 - 7.1e-21 73.9 0.0 1.7e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain SPX PF03105.19 CAR30529.1 - 0.029 14.3 2.1 0.038 13.9 2.1 1.1 1 0 0 1 1 1 0 SPX domain DUF3209 PF11483.8 CAR30529.1 - 0.099 13.1 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DUF1400 PF07176.11 CAR30529.1 - 0.17 12.2 1.3 0.37 11.1 1.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) DKCLD PF08068.12 CAR30530.1 - 2.5e-32 110.7 0.5 2.2e-31 107.7 0.6 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CAR30530.1 - 2.4e-22 78.9 0.4 5.1e-22 77.8 0.4 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CAR30530.1 - 7.2e-21 73.9 1.0 2e-20 72.5 1.1 1.8 2 0 0 2 2 2 1 PUA domain TruB_N PF01509.18 CAR30530.1 - 6.8e-20 72.0 7.9 1.1e-18 68.0 0.0 3.9 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 CAR30530.1 - 0.0045 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain GAGA_bind PF06217.12 CAR30530.1 - 0.39 11.0 16.2 0.53 10.5 16.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DnaJ_C PF01556.18 CAR30531.1 - 1.7e-36 125.6 0.1 2.1e-36 125.2 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR30531.1 - 2.7e-22 78.6 0.4 4.8e-22 77.9 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 CAR30532.1 - 4.4e-42 141.2 16.8 2.9e-10 40.5 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30532.1 - 5.2e-13 49.1 3.3 0.012 15.9 0.1 5.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR30532.1 - 1.9e-10 40.1 8.5 0.0027 16.4 0.1 4.6 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CAR30532.1 - 7.1e-08 31.8 1.0 0.067 12.2 0.0 4.6 1 1 5 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CAR30532.1 - 4.4e-06 25.7 0.7 0.00023 20.0 0.1 3.2 1 1 3 4 4 4 2 Nup133 N terminal like Frtz PF11768.8 CAR30532.1 - 1.7e-05 23.4 0.0 0.00011 20.6 0.0 2.0 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 CAR30532.1 - 0.00085 18.4 1.6 0.0028 16.6 0.0 2.5 3 0 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 CAR30532.1 - 0.0028 17.4 1.6 5.2 6.7 0.0 4.2 2 1 2 4 4 4 2 TUP1-like enhancer of split RFX_DNA_binding PF02257.15 CAR30533.1 - 1.1e-30 106.0 0.0 3.6e-30 104.4 0.0 1.8 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 CAR30533.1 - 0.00038 20.9 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 Poxvirus D5 protein-like Collagen PF01391.18 CAR30533.1 - 3.9 7.3 19.7 6.9 6.5 19.7 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Ribosomal_L30 PF00327.20 CAR30534.1 - 6.5e-12 45.2 0.4 1.7e-11 43.9 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF4023 PF13215.6 CAR30534.1 - 0.47 10.5 5.1 5.8 7.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) DUF572 PF04502.13 CAR30534.1 - 3.4 7.2 12.2 0.82 9.2 9.2 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Iso_dh PF00180.20 CAR30535.1 - 5.9e-127 423.6 0.0 6.7e-127 423.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.18 CAR30535.1 - 0.073 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Aminotran_5 PF00266.19 CAR30536.1 - 7e-98 328.0 0.0 9.4e-98 327.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CAR30536.1 - 1.8e-09 37.4 0.5 1.2e-08 34.7 0.4 2.2 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CAR30536.1 - 3.1e-09 36.5 0.0 4.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 CAR30536.1 - 0.001 17.9 0.1 0.0018 17.0 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CAR30536.1 - 0.005 15.4 1.1 0.0073 14.9 0.9 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Transketolase_C PF02780.20 CAR30536.1 - 0.0094 15.8 0.1 0.023 14.6 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Mito_carr PF00153.27 CAR30537.1 - 8e-50 166.7 6.0 5e-19 68.0 0.2 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein DUF4803 PF16061.5 CAR30537.1 - 0.033 13.6 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) Dcc1 PF09724.9 CAR30538.1 - 9.7e-80 268.4 0.0 1.1e-79 268.2 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF3507 PF12015.8 CAR30539.1 - 8e-57 191.9 0.0 1.6e-56 190.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF1325 PF07039.11 CAR30540.1 - 2e-39 134.7 0.0 3.1e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 CAR30540.1 - 6.1e-06 26.0 0.0 1.7e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 CAR30540.1 - 3.3e-05 24.3 0.1 0.027 14.9 0.1 2.6 2 0 0 2 2 2 2 Agenet domain DUF4537 PF15057.6 CAR30540.1 - 0.0022 18.0 0.0 0.033 14.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) PilZ PF07238.14 CAR30540.1 - 0.01 16.1 0.0 0.18 12.2 0.0 2.4 2 1 0 2 2 2 0 PilZ domain DASH_Dad2 PF08654.10 CAR30540.1 - 0.038 14.4 0.2 0.076 13.4 0.2 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 DHR10 PF18595.1 CAR30540.1 - 0.058 13.5 1.3 0.12 12.5 1.3 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Myosin_tail_1 PF01576.19 CAR30540.1 - 0.063 11.1 1.5 0.079 10.8 1.5 1.0 1 0 0 1 1 1 0 Myosin tail LBR_tudor PF09465.10 CAR30540.1 - 0.093 12.5 0.0 1.7 8.5 0.0 2.6 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain Tudor_2 PF18104.1 CAR30540.1 - 0.18 11.5 0.1 8.6 6.1 0.0 2.8 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Ribosomal_L27_C PF18471.1 CAR30541.1 - 1.4e-92 309.5 16.1 1.6e-92 309.3 16.1 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 CAR30541.1 - 5e-31 106.6 0.1 9.3e-31 105.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein Chordopox_G2 PF05796.12 CAR30541.1 - 0.022 14.2 0.2 0.034 13.6 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus protein G2 ALS_ss_C PF10369.9 CAR30542.1 - 1.3e-15 57.4 0.0 6.5e-15 55.1 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 CAR30542.1 - 2.1e-13 49.8 1.1 2.5e-13 49.5 0.1 1.7 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.6 CAR30542.1 - 4.2e-08 32.9 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.8 CAR30542.1 - 0.013 15.6 0.0 0.076 13.1 0.0 2.2 3 0 0 3 3 3 0 Limkain b1 KH_10 PF17905.1 CAR30542.1 - 0.087 13.3 0.0 0.21 12.0 0.0 1.8 1 1 0 1 1 1 0 GLD-3 KH domain 5 ACT_4 PF13291.6 CAR30542.1 - 0.089 13.4 0.1 0.85 10.3 0.0 2.2 2 0 0 2 2 2 0 ACT domain PLDc_2 PF13091.6 CAR30544.1 - 9e-18 64.4 0.0 5.9e-08 32.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CAR30544.1 - 1.2e-12 47.4 0.5 6.2e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Rer1 PF03248.13 CAR30545.1 - 2.8e-74 248.5 5.5 3.2e-74 248.3 5.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF1980 PF09323.10 CAR30545.1 - 0.095 12.6 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3742 PF12553.8 CAR30545.1 - 0.71 10.0 2.6 1.1 9.4 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) eRF1_2 PF03464.15 CAR30546.1 - 3.5e-28 98.6 0.1 5.8e-28 97.9 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CAR30546.1 - 1.9e-24 86.3 0.0 1.2e-23 83.8 0.0 2.2 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 CAR30546.1 - 1.3e-22 80.2 0.0 1.8e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 Septin PF00735.18 CAR30547.1 - 7.8e-106 353.5 0.7 9.2e-106 353.2 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAR30547.1 - 2.2e-09 37.4 0.1 4e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR30547.1 - 1.5e-08 34.4 0.5 7.9e-06 25.5 0.2 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR30547.1 - 7.9e-08 32.4 0.8 1.2e-06 28.6 0.3 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CAR30547.1 - 7.4e-06 25.4 0.3 1.3e-05 24.7 0.3 1.5 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CAR30547.1 - 0.00015 21.8 0.9 0.22 11.6 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 CAR30547.1 - 0.0014 19.0 0.1 0.0038 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CAR30547.1 - 0.0019 18.7 0.4 0.0042 17.6 0.4 1.7 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CAR30547.1 - 0.0028 17.0 0.1 0.0053 16.1 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.6 CAR30547.1 - 0.0032 17.7 0.0 0.0082 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CAR30547.1 - 0.0066 15.7 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_23 PF13476.6 CAR30547.1 - 0.017 15.6 0.2 0.036 14.6 0.2 1.4 1 1 0 1 1 1 0 AAA domain IIGP PF05049.13 CAR30547.1 - 0.022 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 CAR30547.1 - 0.024 14.8 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CAR30547.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CAR30547.1 - 0.03 14.5 0.7 0.11 12.7 0.7 2.1 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CAR30547.1 - 0.063 12.6 0.6 0.82 9.0 0.6 2.2 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CAR30547.1 - 0.069 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAR30547.1 - 0.08 12.7 0.7 0.24 11.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CAR30547.1 - 0.084 12.4 0.4 2.8 7.4 0.0 2.5 3 0 0 3 3 3 0 Ferrous iron transport protein B Ribosomal_L32p PF01783.23 CAR30548.1 - 9.5e-12 45.0 5.1 9.5e-12 45.0 5.1 1.7 2 0 0 2 2 2 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 CAR30548.1 - 0.0031 16.9 1.4 0.0059 16.0 1.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain Cupin_8 PF13621.6 CAR30549.1 - 7e-11 42.3 0.0 1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CAR30549.1 - 1.7e-10 41.3 0.1 5.1e-10 39.8 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CAR30549.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Elongin_A PF06881.11 CAR30549.1 - 0.045 14.3 0.0 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A GPI PF06560.11 CAR30549.1 - 0.18 11.0 0.0 0.43 9.8 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FMN_red PF03358.15 CAR30550.1 - 8.1e-11 41.9 0.2 1.6e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CAR30550.1 - 3.7e-05 23.5 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CAR30550.1 - 0.00018 21.8 0.1 0.0011 19.2 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 CAR30550.1 - 0.0043 17.3 0.0 0.051 13.8 0.0 2.3 2 1 1 3 3 3 1 Flavodoxin domain PE-PPE PF08237.11 CAR30550.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain Citrate_synt PF00285.21 CAR30551.1 - 4.2e-102 341.9 0.0 5.1e-102 341.6 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Pkinase PF00069.25 CAR30552.1 - 2.8e-49 167.9 0.0 5.4e-49 166.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30552.1 - 2.5e-26 92.5 0.0 3.6e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR30552.1 - 0.001 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR30552.1 - 0.01 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR30552.1 - 0.011 15.7 0.1 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR30552.1 - 0.02 14.4 0.1 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sterol-sensing PF12349.8 CAR30553.1 - 0.00044 20.1 9.8 0.0041 17.0 9.8 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Tir_receptor_C PF07489.11 CAR30553.1 - 0.1 12.6 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus DUF983 PF06170.12 CAR30553.1 - 3.4 8.1 5.1 59 4.2 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF983) BAR PF03114.18 CAR30554.1 - 8.6e-55 186.0 0.6 1.1e-54 185.7 0.6 1.1 1 0 0 1 1 1 1 BAR domain NADH_4Fe-4S PF10589.9 CAR30554.1 - 0.17 12.0 0.0 0.64 10.1 0.0 2.0 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Jnk-SapK_ap_N PF09744.9 CAR30554.1 - 0.82 9.9 6.5 0.56 10.4 0.3 2.6 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Seryl_tRNA_N PF02403.22 CAR30554.1 - 1.2 9.4 6.5 13 6.1 0.2 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4164 PF13747.6 CAR30554.1 - 2.5 8.5 7.4 2.7 8.3 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) S-methyl_trans PF02574.16 CAR30555.1 - 3.4e-50 171.3 0.0 4.4e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase RNA_pol_Rpc34 PF05158.12 CAR30556.1 - 4.5e-104 348.5 0.4 5.9e-104 348.1 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 CAR30556.1 - 0.014 15.8 0.7 0.037 14.4 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator OHA PF14418.6 CAR30556.1 - 0.11 12.3 0.3 0.85 9.5 0.1 2.4 2 0 0 2 2 2 0 OST-HTH Associated domain RPA_C PF08784.11 CAR30556.1 - 0.13 12.9 0.0 0.46 11.2 0.0 2.0 1 1 0 1 1 1 0 Replication protein A C terminal B-block_TFIIIC PF04182.12 CAR30556.1 - 0.17 12.1 1.6 3.1 8.0 0.1 2.4 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC ABC2_membrane PF01061.24 CAR30557.1 - 4.7e-39 134.0 19.8 4.7e-39 134.0 19.8 2.3 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.27 CAR30557.1 - 2.8e-29 102.4 0.0 4.7e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CAR30557.1 - 0.0032 17.4 0.5 0.0062 16.5 0.5 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CAR30557.1 - 0.0036 17.1 1.3 1.7 8.4 0.2 2.6 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR30557.1 - 0.0074 16.0 0.2 0.017 14.9 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CAR30557.1 - 0.092 13.0 0.1 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAR30557.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain EGF_2 PF07974.13 CAR30557.1 - 0.17 12.3 24.4 0.05 14.0 7.7 3.9 3 0 0 3 3 3 0 EGF-like domain SbcCD_C PF13558.6 CAR30557.1 - 0.19 12.0 0.0 0.44 10.8 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 CAR30557.1 - 0.2 11.9 0.1 0.33 11.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR30557.1 - 0.25 11.2 0.6 0.53 10.2 0.6 1.5 1 0 0 1 1 1 0 NACHT domain Peptidase_M28 PF04389.17 CAR30558.1 - 8e-40 136.7 0.0 1.2e-39 136.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SUB1_ProdP9 PF18213.1 CAR30558.1 - 0.13 12.1 0.1 3.1 7.7 0.1 2.4 1 1 0 1 1 1 0 SUB1 protease Prodomain ProdP9 PIP5K PF01504.18 CAR30559.1 - 6.5e-42 143.6 4.1 5.2e-36 124.3 3.0 4.0 4 1 1 5 5 5 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CAR30559.1 - 1.1e-26 93.6 0.1 1.8e-26 92.8 0.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CAR30559.1 - 5.2e-17 61.7 10.5 5.2e-17 61.7 10.5 2.1 2 0 0 2 2 2 1 FYVE zinc finger DUF3410 PF11890.8 CAR30559.1 - 1.2 9.0 3.4 4 7.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3410) DUF3391 PF11871.8 CAR30559.1 - 3.8 8.1 8.5 0.28 11.7 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) WD40 PF00400.32 CAR30560.1 - 1.4e-07 32.1 0.0 0.036 14.9 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30560.1 - 1.8e-06 28.2 0.0 0.0064 16.8 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR30560.1 - 0.011 14.8 0.1 0.033 13.2 0.0 1.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arrestin_C PF02752.22 CAR30561.1 - 4.9e-25 88.5 0.4 4.4e-24 85.4 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CAR30561.1 - 1.5e-08 34.8 0.0 3.9e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CAR30561.1 - 0.0042 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like TMEM61 PF15105.6 CAR30561.1 - 0.089 12.6 1.1 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 TMEM61 protein family zf-C2H2_assoc PF16606.5 CAR30561.1 - 9.8 6.5 10.6 0.68 10.2 3.9 2.5 2 0 0 2 2 2 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF1963 PF09234.10 CAR30562.1 - 3.8e-64 217.1 2.4 4.5e-64 216.8 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1963) Pyr_redox_2 PF07992.14 CAR30563.1 - 1.2e-46 159.3 0.0 1.8e-46 158.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR30563.1 - 1.9e-12 47.5 0.0 1.6e-09 38.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.22 CAR30564.1 - 2.4e-38 129.8 2.4 7.2e-13 48.2 0.1 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR30564.1 - 8.3e-05 22.5 0.2 0.74 9.9 0.0 2.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CAR30564.1 - 0.0019 17.8 0.0 0.44 10.1 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CAR30564.1 - 0.053 13.6 0.1 13 5.9 0.0 3.3 3 0 0 3 3 3 0 RNA binding motif Ysc84 PF04366.12 CAR30565.1 - 3e-41 140.1 0.1 4.4e-41 139.6 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CAR30565.1 - 8.7e-18 63.7 0.1 1.8e-17 62.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR30565.1 - 3.9e-14 52.2 0.0 7.4e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR30565.1 - 8e-13 47.9 0.0 1.5e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TraT PF05818.12 CAR30565.1 - 0.34 10.5 1.0 0.45 10.2 0.1 1.5 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF1776 PF08643.10 CAR30566.1 - 1.1e-38 133.3 6.8 1.8e-37 129.3 6.8 2.2 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) tRNA-synt_2 PF00152.20 CAR30567.1 - 8.4e-89 297.7 0.0 1.5e-88 296.9 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR30567.1 - 2.3e-11 43.5 0.0 5.2e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ProRS-C_1 PF09180.11 CAR30568.1 - 4.8e-27 94.0 2.8 1.1e-26 92.9 2.8 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CAR30568.1 - 1e-17 64.0 0.0 2.6e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CAR30568.1 - 2.6e-16 60.1 0.0 5.8e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CAR30568.1 - 0.036 14.1 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain PHP PF02811.19 CAR30569.1 - 8.7e-12 45.6 0.4 1.6e-11 44.8 0.4 1.5 1 1 0 1 1 1 1 PHP domain DUF3581 PF12119.8 CAR30569.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) DAO PF01266.24 CAR30570.1 - 3.1e-24 86.2 0.0 5.8e-24 85.3 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Acetyltransf_13 PF13880.6 CAR30571.1 - 1.8e-20 72.7 0.0 5.2e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CAR30571.1 - 5.7e-11 42.1 0.2 1e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 CAR30571.1 - 8.4e-07 29.2 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAR30571.1 - 3.7e-05 24.1 0.0 9.1e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAR30571.1 - 0.00042 20.3 0.0 0.0027 17.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CAR30571.1 - 0.007 17.0 0.0 0.011 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 CAR30571.1 - 0.027 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 CAR30571.1 - 0.089 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DSPn PF14671.6 CAR30572.1 - 6.8e-45 153.0 0.0 2.4e-44 151.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CAR30572.1 - 1.5e-23 83.0 0.0 5.9e-22 77.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR30572.1 - 0.00032 20.3 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CAR30572.1 - 0.011 15.4 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CAR30572.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate SNARE PF05739.19 CAR30573.1 - 1.8e-15 56.7 0.3 1.8e-15 56.7 0.3 2.0 2 0 0 2 2 2 1 SNARE domain DUF3357 PF11837.8 CAR30573.1 - 0.14 12.6 0.1 0.61 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) TssO PF17561.2 CAR30573.1 - 2.3 8.3 0.0 2.3 8.3 0.0 3.3 3 1 0 3 3 3 0 Type VI secretion system, TssO SUR7 PF06687.12 CAR30574.1 - 1.5e-15 57.4 17.3 2.5e-15 56.7 17.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Wzy_C PF04932.15 CAR30574.1 - 0.0082 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 O-Antigen ligase DUF1690 PF07956.11 CAR30575.1 - 3.5e-40 137.6 11.2 4e-40 137.4 11.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) CHCH PF06747.13 CAR30575.1 - 0.035 14.2 0.4 0.066 13.4 0.4 1.5 1 0 0 1 1 1 0 CHCH domain DUF573 PF04504.14 CAR30575.1 - 0.39 11.4 4.9 7.8 7.2 0.5 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Exonuc_VII_L PF02601.15 CAR30575.1 - 0.57 9.7 5.4 0.65 9.5 5.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GvpL_GvpF PF06386.11 CAR30575.1 - 0.79 9.6 4.4 2.4 8.0 4.3 1.8 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF UCH PF00443.29 CAR30576.1 - 8.1e-51 173.0 1.9 1e-50 172.7 1.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR30576.1 - 3.8e-13 49.7 11.5 3.5e-11 43.3 11.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CAR30576.1 - 0.067 13.0 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family Tam41_Mmp37 PF09139.11 CAR30576.1 - 2 7.8 6.2 9 5.6 0.7 2.9 3 0 0 3 3 3 0 Phosphatidate cytidylyltransferase, mitochondrial Sugar_tr PF00083.24 CAR30577.1 - 6.4e-117 391.2 24.0 8.3e-117 390.8 24.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30577.1 - 9.5e-25 87.3 37.5 1.5e-20 73.5 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.21 CAR30578.1 - 3.4e-121 405.2 41.4 4.1e-121 404.9 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR30578.1 - 1.8e-32 112.7 41.5 2.3e-32 112.4 41.5 1.1 1 0 0 1 1 1 1 Amino acid permease RNB PF00773.19 CAR30579.1 - 2.7e-98 329.3 0.0 3.6e-98 328.9 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 CAR30579.1 - 8.9e-70 233.1 0.1 2.5e-69 231.7 0.1 1.8 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CAR30579.1 - 8.9e-30 102.5 2.0 9.7e-30 102.4 0.4 2.0 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 CAR30579.1 - 1e-17 63.9 0.0 2.2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CAR30579.1 - 1.5e-14 54.4 0.2 3.5e-14 53.2 0.2 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CAR30579.1 - 0.0001 22.4 0.0 0.031 14.4 0.0 2.9 2 0 0 2 2 2 1 Cold shock domain OB_RNB PF08206.11 CAR30579.1 - 0.0049 16.5 0.0 0.014 15.0 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease B OB domain ABC_tran PF00005.27 CAR30580.1 - 2.3e-46 157.7 0.4 2.9e-22 79.7 0.0 3.3 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CAR30580.1 - 2.2e-20 72.5 9.9 2.2e-20 72.5 9.9 3.0 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 CAR30580.1 - 4e-17 63.0 16.5 2e-05 24.5 0.0 5.3 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR30580.1 - 2e-10 40.5 4.4 0.00031 20.2 0.1 3.9 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CAR30580.1 - 2.6e-08 34.3 0.0 0.004 17.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CAR30580.1 - 4.2e-08 33.8 0.7 0.088 13.4 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 CAR30580.1 - 3e-07 31.0 0.2 0.045 14.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CAR30580.1 - 5.3e-07 30.0 1.7 0.023 15.0 0.0 3.5 3 2 0 3 3 2 2 AAA domain NACHT PF05729.12 CAR30580.1 - 2.2e-06 27.7 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 CAR30580.1 - 6.5e-06 25.8 0.0 0.21 11.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CAR30580.1 - 6.9e-06 26.1 0.2 0.094 12.8 0.2 3.3 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_14 PF13173.6 CAR30580.1 - 7.2e-06 26.1 0.0 0.18 11.8 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CAR30580.1 - 2.6e-05 24.6 0.0 0.1 13.0 0.0 3.8 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CAR30580.1 - 2.6e-05 24.0 0.0 0.081 12.6 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_23 PF13476.6 CAR30580.1 - 3e-05 24.6 33.2 0.045 14.2 0.0 5.3 5 1 0 5 5 4 3 AAA domain RsgA_GTPase PF03193.16 CAR30580.1 - 3.2e-05 23.9 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CAR30580.1 - 3.7e-05 23.6 21.3 0.0093 15.7 0.0 5.0 4 1 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.6 CAR30580.1 - 4.3e-05 23.7 0.7 0.077 13.2 0.0 3.2 3 1 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.25 CAR30580.1 - 5.5e-05 22.9 0.0 0.084 12.5 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 CAR30580.1 - 0.00016 22.0 0.3 0.41 11.1 0.0 3.5 4 0 0 4 4 3 1 RNA helicase AAA_24 PF13479.6 CAR30580.1 - 0.00023 20.9 0.0 1.1 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 CAR30580.1 - 0.00081 18.6 0.1 0.47 9.6 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.9 CAR30580.1 - 0.0012 18.6 0.1 0.54 10.0 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CAR30580.1 - 0.0015 17.6 0.1 0.76 8.7 0.0 2.9 2 1 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CAR30580.1 - 0.0021 18.3 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CAR30580.1 - 0.0026 17.1 0.0 1.5 8.0 0.0 2.6 2 0 0 2 2 2 1 Septin MobB PF03205.14 CAR30580.1 - 0.0031 17.4 0.0 0.093 12.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_7 PF12775.7 CAR30580.1 - 0.006 16.1 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 CAR30580.1 - 0.0071 16.6 0.2 7 7.0 0.1 3.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CAR30580.1 - 0.0072 15.6 0.0 2 7.7 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 CAR30580.1 - 0.0083 16.1 8.2 0.22 11.4 0.0 3.3 4 0 0 4 4 2 2 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CAR30580.1 - 0.0084 16.0 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.23 CAR30580.1 - 0.011 15.7 0.4 0.011 15.7 0.4 3.7 3 1 1 4 4 3 0 Dynamin family Rad17 PF03215.15 CAR30580.1 - 0.013 15.4 0.0 0.33 10.9 0.0 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain AAA_27 PF13514.6 CAR30580.1 - 0.014 15.0 0.2 5.1 6.6 0.0 3.5 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 CAR30580.1 - 0.017 15.1 0.0 12 5.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CAR30580.1 - 0.019 14.7 0.0 0.7 9.6 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase cobW PF02492.19 CAR30580.1 - 0.02 14.5 0.0 3.2 7.3 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 CAR30580.1 - 0.022 14.3 0.9 0.34 10.3 0.0 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 CAR30580.1 - 0.039 13.3 0.1 1.8 7.9 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 CAR30580.1 - 0.044 12.7 0.1 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FeoB_N PF02421.18 CAR30580.1 - 0.05 13.1 0.0 8.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 CAR30580.1 - 0.062 12.9 0.3 2.8 7.5 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 CAR30580.1 - 0.063 13.3 0.0 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CAR30580.1 - 0.07 12.7 0.0 3.5 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CAR30580.1 - 0.084 13.2 0.0 0.41 11.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain Ras PF00071.22 CAR30580.1 - 0.088 12.4 1.2 12 5.4 0.0 3.3 3 0 0 3 3 3 0 Ras family AAA_17 PF13207.6 CAR30580.1 - 0.16 12.4 4.0 12 6.3 0.0 3.7 3 1 0 3 3 3 0 AAA domain Helo_like_N PF17111.5 CAR30580.1 - 0.2 11.0 4.3 0.34 10.2 0.5 3.2 4 0 0 4 4 3 0 Fungal N-terminal domain of STAND proteins DUF87 PF01935.17 CAR30580.1 - 0.39 10.8 0.0 0.39 10.8 0.0 5.1 5 1 1 6 6 5 0 Helicase HerA, central domain dNK PF01712.19 CAR30580.1 - 0.63 9.9 0.0 0.63 9.9 0.0 3.5 5 0 0 5 5 2 0 Deoxynucleoside kinase NPV_P10 PF05531.12 CAR30580.1 - 3.5 8.2 5.4 22 5.6 0.4 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PDCD2_C PF04194.13 CAR30581.1 - 2.9e-44 151.2 0.3 4.3e-40 137.6 0.0 2.8 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain GTP_EFTU PF00009.27 CAR30582.1 - 4.5e-31 107.9 5.7 2.7e-30 105.4 2.4 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CAR30582.1 - 8.2e-23 80.5 0.5 2.5e-22 79.0 0.5 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CAR30582.1 - 1.4e-08 34.8 0.5 4.5e-08 33.2 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.15 CAR30582.1 - 2e-08 33.9 0.0 5.6e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 CAR30582.1 - 4.4e-05 23.8 7.0 0.018 15.4 0.2 3.9 3 1 1 4 4 3 2 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CAR30582.1 - 0.0013 18.7 1.4 0.03 14.2 0.4 2.6 1 1 1 2 2 2 1 RsgA GTPase Ras PF00071.22 CAR30582.1 - 0.01 15.5 0.1 0.11 12.1 0.0 2.3 2 0 0 2 2 2 0 Ras family Roc PF08477.13 CAR30582.1 - 0.017 15.4 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CAR30582.1 - 0.088 12.6 0.6 0.59 9.9 0.2 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CAR30582.1 - 0.096 12.1 0.0 0.096 12.1 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CAR30582.1 - 0.96 9.5 8.8 9.1 6.3 0.0 4.3 4 2 2 6 6 6 0 Dynamin family Iron_permease PF04120.12 CAR30583.1 - 3.4e-32 110.9 21.1 1.6e-16 60.3 2.4 4.6 5 0 0 5 5 5 4 Low affinity iron permease DUF1003 PF06210.11 CAR30583.1 - 1.3 9.1 3.8 33 4.6 1.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) TauD PF02668.16 CAR30584.1 - 4.1e-33 115.3 0.0 6.4e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CAR30584.1 - 2e-06 28.3 0.1 0.0044 17.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.10 CAR30584.1 - 0.0006 19.0 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 CsiD TIP120 PF08623.10 CAR30586.1 - 4.4e-09 36.3 0.0 4.5e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) PGK PF00162.19 CAR30587.1 - 1.8e-152 507.7 0.7 2.1e-152 507.5 0.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DNA_pol_B_thumb PF14791.6 CAR30588.1 - 1.3e-21 76.5 0.0 3.8e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CAR30588.1 - 1e-20 74.0 0.1 3e-20 72.5 0.1 1.9 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.9 CAR30588.1 - 1.3e-14 53.7 0.2 9e-14 51.0 0.1 2.3 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 CAR30588.1 - 2.2e-14 53.6 0.0 9.1e-14 51.6 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT_2 PF16589.5 CAR30588.1 - 4.6e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain NTP_transf_2 PF01909.23 CAR30588.1 - 0.0092 16.3 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain BRCT PF00533.26 CAR30588.1 - 0.1 13.0 0.0 0.5 10.8 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain HAD PF12710.7 CAR30589.1 - 6.5e-06 26.7 0.0 0.0013 19.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2373 PF10180.9 CAR30590.1 - 5.8e-25 86.9 0.0 9.3e-25 86.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Sugar_tr PF00083.24 CAR30591.1 - 5.5e-109 365.0 24.0 7e-109 364.7 24.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30591.1 - 1.2e-26 93.5 15.7 1.2e-26 93.5 15.7 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2561 PF10812.8 CAR30591.1 - 0.16 12.0 1.8 0.29 11.1 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) MFS_1_like PF12832.7 CAR30591.1 - 1.2 7.9 17.6 0.22 10.4 0.6 3.0 2 1 1 3 3 3 0 MFS_1 like family Swm2 PF17083.5 CAR30592.1 - 7.2e-30 103.7 0.0 8.3e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein Swm2 Frag1 PF10277.9 CAR30593.1 - 6.9e-29 100.9 14.5 6.9e-29 100.9 14.5 4.0 3 2 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CAR30593.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Alpha-amylase_C PF02806.18 CAR30594.1 - 4.7e-25 87.9 0.1 1.6e-24 86.2 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CAR30594.1 - 1.1e-15 57.8 0.0 2.4e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CAR30594.1 - 8.7e-15 55.1 0.2 4.1e-14 52.9 0.1 2.1 1 1 1 2 2 2 1 Alpha amylase, catalytic domain UQ_con PF00179.26 CAR30595.1 - 9.1e-40 135.5 0.1 1.2e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR30595.1 - 0.081 13.2 0.1 0.16 12.2 0.1 1.8 1 1 0 1 1 1 0 RWD domain BUD22 PF09073.10 CAR30595.1 - 3.5 6.9 10.8 3.9 6.7 10.8 1.1 1 0 0 1 1 1 0 BUD22 HalX PF08663.10 CAR30596.1 - 0.022 15.1 3.3 0.044 14.1 3.3 1.5 1 0 0 1 1 1 0 HalX domain TENA_THI-4 PF03070.16 CAR30597.1 - 1.2e-09 38.3 1.3 1.6e-09 37.9 1.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 CAR30598.1 - 0.0016 17.8 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Arm PF00514.23 CAR30599.1 - 1.2e-68 225.2 33.8 5e-11 42.2 0.3 11.2 11 1 1 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CAR30599.1 - 5.3e-20 71.5 17.4 0.00022 21.6 0.2 8.2 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 CAR30599.1 - 3.1e-14 53.1 9.7 0.00086 19.7 0.0 7.0 3 2 6 9 9 9 4 HEAT repeats HEAT PF02985.22 CAR30599.1 - 4e-12 45.3 23.7 0.23 11.8 0.2 9.6 10 0 0 10 10 9 5 HEAT repeat Adaptin_N PF01602.20 CAR30599.1 - 2.2e-11 43.0 11.0 2.3e-06 26.5 2.8 2.8 1 1 2 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 CAR30599.1 - 2.5e-09 37.0 8.0 6e-07 29.2 4.3 2.6 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.12 CAR30599.1 - 4.9e-09 34.9 0.8 9.6e-07 27.3 0.0 2.6 1 1 2 3 3 3 2 Kinesin-associated protein (KAP) Cnd1 PF12717.7 CAR30599.1 - 2.8e-05 24.2 11.2 0.064 13.3 0.1 4.8 2 1 3 6 6 6 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 CAR30599.1 - 3.5e-05 23.2 3.4 0.00078 18.8 0.3 3.2 1 1 3 4 4 4 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 CAR30599.1 - 0.00029 20.9 6.7 0.036 14.2 0.2 5.1 4 2 1 6 6 6 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 CAR30599.1 - 0.0003 21.3 1.3 0.36 11.4 0.0 3.8 3 2 1 4 4 4 1 Vacuolar 14 Fab1-binding region Tti2 PF10521.9 CAR30599.1 - 0.00065 19.3 0.0 0.019 14.5 0.0 2.8 3 0 0 3 3 3 1 Tti2 family DUF3361 PF11841.8 CAR30599.1 - 0.0021 18.0 11.1 0.032 14.2 0.6 4.5 3 2 2 5 5 5 1 Domain of unknown function (DUF3361) RIF5_SNase_1 PF18187.1 CAR30599.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 DUF5578 PF17741.1 CAR30599.1 - 0.031 13.7 6.6 3.6 6.9 0.2 4.2 2 1 2 4 4 4 0 Family of unknown function (DUF5578) YqfD PF06898.11 CAR30599.1 - 0.064 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD YjeF_N PF03853.15 CAR30600.1 - 2.2e-31 109.0 0.1 6.1e-31 107.6 0.0 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus FDF PF09532.10 CAR30600.1 - 3.3e-08 34.4 5.7 6.1e-08 33.5 5.7 1.5 1 0 0 1 1 1 1 FDF domain Ras PF00071.22 CAR30601.1 - 2.1e-42 144.5 0.0 2.4e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR30601.1 - 1.7e-13 50.8 0.0 2.2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR30601.1 - 2.2e-09 37.0 0.0 2.6e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR30601.1 - 2.8e-07 30.6 0.1 4.2e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR30601.1 - 1e-06 28.4 0.5 0.00012 21.6 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAR30601.1 - 0.00058 19.4 0.1 0.0049 16.4 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CAR30601.1 - 0.00084 18.8 0.2 0.0011 18.4 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 CAR30601.1 - 0.023 14.8 0.0 0.039 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CAR30601.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea adh_short_C2 PF13561.6 CAR30602.1 - 2.6e-44 151.5 0.4 1.9e-31 109.5 0.1 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR30602.1 - 4e-31 108.0 1.1 9.1e-29 100.3 1.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR30602.1 - 7.9e-10 38.9 0.2 2.4e-09 37.4 0.1 1.9 1 1 1 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 CAR30602.1 - 2.7e-05 23.7 0.1 9.7e-05 21.9 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CAR30602.1 - 0.00022 20.8 0.2 0.00045 19.7 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CAR30602.1 - 0.00027 20.2 0.0 0.00036 19.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 CAR30602.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_transf_5 PF08323.11 CAR30602.1 - 0.13 11.9 0.0 4.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain AF-4 PF05110.13 CAR30603.1 - 0.38 8.8 2.1 0.42 8.6 2.1 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-Nse PF11789.8 CAR30605.1 - 1.7e-20 72.5 0.2 1.7e-20 72.5 0.2 2.2 3 0 0 3 3 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CAR30605.1 - 4.1e-05 23.5 2.0 9.9e-05 22.3 2.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR30605.1 - 0.00042 20.1 0.7 0.00091 19.0 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR30605.1 - 0.0021 18.4 1.7 0.0042 17.4 1.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CAR30605.1 - 0.025 14.9 0.1 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CAR30605.1 - 0.029 14.0 0.4 0.048 13.3 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CAR30605.1 - 0.037 14.1 1.1 0.067 13.3 1.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CEP63 PF17045.5 CAR30605.1 - 0.041 13.8 0.2 0.066 13.1 0.2 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa zf-MIZ PF02891.20 CAR30605.1 - 0.049 13.4 1.1 0.049 13.4 1.1 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Rtf2 PF04641.12 CAR30605.1 - 0.052 12.9 0.1 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4 PF00097.25 CAR30605.1 - 0.054 13.4 0.3 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YabA PF06156.13 CAR30605.1 - 0.1 13.2 0.0 0.36 11.5 0.0 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Occludin_ELL PF07303.13 CAR30605.1 - 0.15 12.8 0.2 1.2 9.9 0.1 2.4 3 0 0 3 3 3 0 Occludin homology domain zf-RING_5 PF14634.6 CAR30605.1 - 0.27 11.2 1.6 0.5 10.4 1.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain tRNA-synt_2 PF00152.20 CAR30606.1 - 5.1e-79 265.6 0.0 6.2e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR30606.1 - 4.9e-08 32.8 0.0 8.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAR30606.1 - 0.018 14.5 0.0 4.6 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) TPP_enzyme_N PF02776.18 CAR30607.1 - 1e-41 142.4 0.0 8.4e-41 139.4 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CAR30607.1 - 7.1e-27 94.1 0.1 3.6e-26 91.8 0.4 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR30607.1 - 3.1e-25 88.5 0.0 6.2e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 CAR30607.1 - 0.055 12.7 0.9 0.094 11.9 0.4 1.5 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase RLAN PF14401.6 CAR30607.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain Peripla_BP_4 PF13407.6 CAR30607.1 - 0.18 11.3 2.0 0.96 9.0 0.4 2.6 2 1 0 2 2 2 0 Periplasmic binding protein domain zf-Tim10_DDP PF02953.15 CAR30608.1 - 4e-21 74.4 7.7 5.8e-21 73.9 7.7 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 CAR30608.1 - 0.021 15.1 0.1 0.3 11.4 0.0 2.0 1 1 1 2 2 2 0 Phasin protein Tam41_Mmp37 PF09139.11 CAR30608.1 - 0.054 12.9 0.6 0.059 12.8 0.6 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial DUF842 PF05811.13 CAR30608.1 - 0.11 12.2 7.2 2.2 8.0 0.7 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) OMPdecase PF00215.24 CAR30609.1 - 1.3e-74 250.6 0.0 1.6e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.27 CAR30610.1 - 5.6e-12 45.4 2.0 6.7e-08 32.3 0.1 2.8 3 1 0 3 3 3 2 Mitochondrial carrier protein Mob1_phocein PF03637.17 CAR30610.1 - 0.086 12.9 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Mob1/phocein family Sec7 PF01369.20 CAR30611.1 - 2.4e-67 226.2 1.1 6.7e-67 224.7 1.1 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CAR30611.1 - 1.2e-14 54.5 2.1 1.2e-14 54.5 2.1 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CAR30611.1 - 1.1e-05 25.1 11.9 0.0002 21.1 2.4 3.9 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF2683 PF10884.8 CAR30611.1 - 0.012 15.9 1.7 0.079 13.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2683) IFN-gamma PF00714.17 CAR30611.1 - 1.6 8.6 6.4 0.95 9.3 1.4 2.9 2 0 0 2 2 2 0 Interferon gamma Pro_isomerase PF00160.21 CAR30612.1 - 7.7e-40 136.8 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 CAR30612.1 - 2.1e-09 36.8 19.2 1.6e-07 30.9 0.9 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR30612.1 - 1e-08 34.6 15.4 6.8e-06 25.8 0.4 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR30612.1 - 7.4e-05 23.0 0.3 0.0019 18.4 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR30612.1 - 9.3e-05 23.0 0.9 0.0004 21.0 0.0 2.5 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR30612.1 - 0.0091 16.5 0.5 0.97 10.0 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR30612.1 - 0.01 16.4 2.0 0.29 11.9 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR30612.1 - 0.053 13.8 16.2 0.09 13.0 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR30612.1 - 0.15 12.3 8.2 0.29 11.4 1.1 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CAR30612.1 - 0.22 12.4 0.2 7 7.8 0.0 3.1 4 0 0 4 4 2 0 Tetratricopeptide repeat MIT PF04212.18 CAR30612.1 - 2 8.5 5.5 0.72 10.0 0.2 2.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Rav1p_C PF12234.8 CAR30613.1 - 2.4e-236 786.1 5.1 4.4e-235 782.0 0.9 2.2 2 0 0 2 2 2 2 RAVE protein 1 C terminal Pet191_N PF10203.9 CAR30614.1 - 3.5e-24 84.9 4.5 5.7e-24 84.2 4.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CAR30614.1 - 0.075 13.1 6.8 3.5 7.7 0.4 3.1 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SNF2_N PF00176.23 CAR30615.1 - 2.4e-73 246.9 0.0 4e-73 246.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR30615.1 - 8.5e-21 74.4 0.0 5.4e-20 71.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30615.1 - 5.2e-08 33.1 0.0 2.8e-07 30.7 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIE_beta PF02186.15 CAR30615.1 - 0.043 14.1 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 TFIIE beta subunit core domain Allexi_40kDa PF05549.11 CAR30615.1 - 0.52 9.8 3.9 1.2 8.6 3.9 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2235 PF09994.9 CAR30616.1 - 3.8e-81 272.6 0.0 5e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CBM46 PF18448.1 CAR30616.1 - 0.093 13.1 0.3 1.1 9.6 0.1 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain Rieske PF00355.26 CAR30617.1 - 1.4e-11 44.2 0.0 2.8e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CAR30617.1 - 7.2e-11 42.4 0.5 1.9e-10 41.1 0.5 1.7 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Transp_cyt_pur PF02133.15 CAR30617.1 - 0.12 11.1 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Permease for cytosine/purines, uracil, thiamine, allantoin HECT PF00632.25 CAR30618.1 - 5.2e-75 252.8 0.1 1e-74 251.8 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L7Ae PF01248.26 CAR30620.1 - 7e-28 96.2 0.0 8.3e-28 96.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CAR30620.1 - 0.00093 19.0 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Pico_P2B PF01552.17 CAR30620.1 - 0.0059 16.7 0.0 0.012 15.8 0.0 1.5 1 1 1 2 2 2 1 Picornavirus 2B protein RNase_P_pop3 PF08228.11 CAR30620.1 - 0.012 15.7 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 Voltage_CLC PF00654.20 CAR30621.1 - 5.2e-75 252.9 26.6 5.2e-75 252.9 26.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CAR30621.1 - 7.5e-08 32.7 0.0 0.023 15.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain Urb2 PF10441.9 CAR30622.1 - 2.8e-56 190.7 0.8 2.8e-56 190.7 0.8 3.7 4 1 0 4 4 4 1 Urb2/Npa2 family CDC37_M PF08565.11 CAR30622.1 - 0.007 16.3 0.1 0.032 14.2 0.1 2.2 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain ESCRT-II PF05871.12 CAR30622.1 - 0.048 13.9 0.1 0.25 11.6 0.1 2.3 1 0 0 1 1 1 0 ESCRT-II complex subunit DUF4194 PF13835.6 CAR30622.1 - 0.072 12.8 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4194) Nucleopor_Nup85 PF07575.13 CAR30623.1 - 1.1e-180 602.0 7.2 1.3e-180 601.8 7.2 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin ATP-synt_C PF00137.21 CAR30624.1 - 1.5e-34 118.1 30.6 2.3e-22 79.1 13.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2244 PF10003.9 CAR30624.1 - 4.4 7.0 5.0 0.83 9.3 0.7 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) CDC27 PF09507.10 CAR30625.1 - 0.0018 17.7 33.3 0.21 11.0 33.3 2.5 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Casc1_N PF15927.5 CAR30625.1 - 4.6 6.9 14.3 10 5.7 14.3 1.5 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus adh_short_C2 PF13561.6 CAR30626.1 - 3e-53 180.8 0.2 3.6e-53 180.5 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR30626.1 - 2.3e-37 128.3 0.2 2.7e-37 128.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR30626.1 - 6.3e-11 42.5 1.7 1.7e-10 41.1 0.4 1.9 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 CAR30626.1 - 4.6e-06 26.3 0.1 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR30626.1 - 0.0017 17.4 0.2 0.0058 15.7 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 CAR30626.1 - 0.062 13.9 0.1 0.12 13.0 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CAR30626.1 - 0.21 11.4 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phos_pyr_kin PF08543.12 CAR30627.1 - 7.1e-12 45.2 0.0 8.7e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CAR30627.1 - 5.1e-07 29.3 0.0 7.3e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MaoC_dehydrat_N PF13452.6 CAR30628.1 - 0.0059 16.7 0.0 0.15 12.2 0.0 2.4 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase MaoC_dehydratas PF01575.19 CAR30628.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 MaoC like domain Dip PF17679.1 CAR30628.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 gp37/Dip protein Ins_P5_2-kin PF06090.12 CAR30629.1 - 1.1e-18 67.8 0.6 2.7e-17 63.2 0.6 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DS PF01916.17 CAR30630.1 - 2.6e-132 440.4 0.0 3.1e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase PCNA_N PF00705.18 CAR30630.1 - 0.12 12.1 0.2 0.25 11.0 0.2 1.5 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Methyltransf_23 PF13489.6 CAR30631.1 - 2.2e-22 79.7 0.0 3.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR30631.1 - 2.4e-12 47.4 0.3 9.9e-12 45.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR30631.1 - 3.1e-11 43.8 0.0 9.1e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR30631.1 - 9.6e-09 35.8 0.0 5.4e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR30631.1 - 1.1e-08 34.7 0.0 3.6e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CAR30631.1 - 3e-07 30.3 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RIC3 PF15361.6 CAR30631.1 - 0.17 12.2 0.6 0.31 11.4 0.6 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ECR1_N PF14382.6 CAR30632.1 - 1.6e-17 63.0 0.2 3.6e-17 61.9 0.2 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CAR30632.1 - 2.6e-09 37.3 0.2 6.2e-09 36.1 0.2 1.7 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 CAR30632.1 - 0.044 14.4 0.7 15 6.2 0.0 3.3 4 0 0 4 4 4 0 Exosome component EXOSC1/CSL4 Met_10 PF02475.16 CAR30633.1 - 1.1e-72 244.0 0.0 1.6e-72 243.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.15 CAR30633.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cyclin_N PF00134.23 CAR30634.1 - 2.7e-10 40.1 1.4 3.8e-10 39.6 1.4 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CAR30634.1 - 4.3e-05 24.0 0.3 5.4e-05 23.6 0.3 1.1 1 0 0 1 1 1 1 Cyclin HIM1 PF08732.10 CAR30635.1 - 2.2e-57 193.2 0.0 3.3e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 HIM1 CENP-O PF09496.10 CAR30636.1 - 5.2e-13 49.5 0.0 1.4e-12 48.1 0.0 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Cnn_1N PF07989.11 CAR30636.1 - 1.1 9.4 4.7 0.58 10.4 1.7 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Scs3p PF10261.9 CAR30637.1 - 3.4e-22 79.2 11.9 3.4e-14 53.0 1.4 2.4 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 CAR30637.1 - 4.5e-05 23.2 1.7 6.8e-05 22.6 1.1 1.7 1 1 0 1 1 1 1 PAP2 superfamily Orai-1 PF07856.12 CAR30637.1 - 0.032 13.9 1.6 0.088 12.5 1.6 1.8 1 1 0 1 1 1 0 Mediator of CRAC channel activity Holin_BhlA PF10960.8 CAR30637.1 - 0.047 13.6 1.7 0.94 9.5 0.0 2.9 3 0 0 3 3 3 0 BhlA holin family Ac76 PF05814.11 CAR30637.1 - 0.19 11.8 4.3 2.1 8.4 0.0 3.3 4 0 0 4 4 4 0 Orf76 (Ac76) SQHop_cyclase_C PF13243.6 CAR30638.1 - 2.4e-44 151.8 0.1 5.9e-44 150.5 0.0 1.6 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CAR30638.1 - 1.8e-32 112.6 0.0 1.5e-27 96.5 0.0 2.9 3 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CAR30638.1 - 1.1e-28 98.7 2.5 3.2e-10 39.6 0.3 5.0 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 CAR30638.1 - 0.0011 18.4 0.3 0.5 9.6 0.0 3.1 2 1 1 3 3 3 2 Pectic acid lyase Ubiq-assoc PF09145.10 CAR30639.1 - 3.5e-25 87.7 2.8 7e-25 86.8 1.1 2.2 2 0 0 2 2 2 1 Ubiquitin-associated TPR_1 PF00515.28 CAR30639.1 - 2e-08 33.7 8.5 0.0071 16.1 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR30639.1 - 6.5e-08 32.1 7.8 0.094 12.9 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR30639.1 - 1.1e-07 31.3 2.0 0.012 15.5 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR30639.1 - 4.7e-07 30.0 0.5 0.086 13.1 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 CAR30639.1 - 0.00038 20.5 2.6 0.22 11.6 0.3 3.8 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CAR30639.1 - 0.0047 17.5 4.9 0.75 10.6 0.2 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR30639.1 - 0.011 15.9 0.1 12 6.1 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 CAR30639.1 - 0.065 13.4 0.3 0.2 11.8 0.1 2.0 2 0 0 2 2 1 0 DnaJ domain TPR_16 PF13432.6 CAR30639.1 - 0.15 12.7 0.8 5.5 7.7 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CAR30639.1 - 0.3 10.6 2.4 22 4.6 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR TPR_11 PF13414.6 CAR30639.1 - 4 7.2 6.9 12 5.7 1.2 3.5 4 0 0 4 4 4 0 TPR repeat Nop10p PF04135.12 CAR30640.1 - 6.9e-22 77.2 0.9 7.8e-22 77.1 0.9 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DASH_Dad4 PF08650.10 CAR30641.1 - 4.3e-34 116.3 8.0 4.7e-34 116.2 8.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.12 CAR30641.1 - 0.0038 17.7 0.3 0.0044 17.5 0.3 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein BCAS2 PF05700.11 CAR30641.1 - 0.014 15.1 0.7 0.014 15.1 0.7 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) SKA1 PF07160.12 CAR30641.1 - 0.021 14.7 1.2 0.022 14.6 1.2 1.0 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FbpA PF05833.11 CAR30641.1 - 0.023 13.5 0.4 0.027 13.2 0.4 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Pox_A32 PF04665.12 CAR30641.1 - 0.032 13.7 1.1 0.036 13.5 1.1 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Gasdermin_C PF17708.1 CAR30641.1 - 0.037 14.2 0.0 0.038 14.1 0.0 1.0 1 0 0 1 1 1 0 Gasdermin PUB domain DUF3251 PF11622.8 CAR30641.1 - 0.072 12.7 0.5 0.083 12.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) DivIC PF04977.15 CAR30641.1 - 0.1 12.4 0.8 0.14 12.0 0.8 1.2 1 0 0 1 1 1 0 Septum formation initiator Oxysterol_BP PF01237.18 CAR30642.1 - 5.7e-103 344.6 6.6 4.2e-102 341.8 6.6 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CAR30642.1 - 8e-30 103.0 0.8 1.9e-29 101.8 0.3 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CAR30642.1 - 0.00016 22.2 0.3 0.00052 20.5 0.3 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CAR30642.1 - 0.32 11.4 3.3 3.8 8.0 3.3 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain Asparaginase PF00710.20 CAR30643.1 - 8.1e-55 185.3 0.0 1.1e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CAR30643.1 - 1.7e-15 57.3 0.0 4.1e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain DUF3982 PF13138.6 CAR30643.1 - 0.0011 18.6 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3982) Ribosomal_L19 PF01245.20 CAR30643.1 - 0.0064 16.4 0.0 2.5 8.1 0.0 2.8 3 0 0 3 3 3 2 Ribosomal protein L19 DIOX_N PF14226.6 CAR30644.1 - 8.7e-16 58.7 1.0 1.7e-15 57.8 0.6 1.7 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CAR30644.1 - 3.8e-15 56.2 0.0 1.8e-14 54.1 0.0 2.1 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily CN_hydrolase PF00795.22 CAR30645.1 - 5.6e-43 147.2 0.0 7.7e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CAR30645.1 - 5.8e-23 81.3 0.0 2.1e-22 79.4 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Abhydrolase_6 PF12697.7 CAR30646.1 - 1.1e-20 75.2 2.1 1.1e-20 75.2 2.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAR30646.1 - 9.1e-14 51.7 0.1 1.2e-13 51.3 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR30646.1 - 2.8e-08 33.3 0.0 4.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CAR30646.1 - 0.0021 18.2 0.8 0.031 14.4 0.8 2.3 1 1 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 CAR30646.1 - 0.0037 17.1 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) zf-C2H2_4 PF13894.6 CAR30647.1 - 0.00028 21.5 18.8 0.0064 17.2 1.7 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR30647.1 - 0.00069 19.9 14.1 0.0011 19.3 0.5 3.3 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CAR30647.1 - 0.0012 19.1 2.0 0.0012 19.1 2.0 3.5 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 CAR30647.1 - 0.074 12.8 0.8 0.074 12.8 0.8 2.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 CAR30647.1 - 5.1 7.5 8.2 2.2 8.6 0.2 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_7 PF15269.6 CAR30647.1 - 6.5 6.9 8.0 1.1 9.3 1.0 2.4 1 1 1 2 2 2 0 Zinc-finger RGS PF00615.19 CAR30648.1 - 1.7e-06 28.3 2.4 1.8e-06 28.2 0.3 2.1 2 1 0 2 2 2 1 Regulator of G protein signaling domain LptF_LptG PF03739.14 CAR30648.1 - 0.0021 17.0 0.0 0.0035 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide export system permease LptF/LptG Usg PF06233.12 CAR30648.1 - 0.17 12.1 1.5 3.5 7.9 0.2 2.8 3 0 0 3 3 3 0 Usg-like family GATase PF00117.28 CAR30649.1 - 2.5e-45 154.6 0.0 3.6e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CAR30649.1 - 2.1e-44 150.4 0.0 3.6e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 CAR30649.1 - 5.7e-05 23.0 0.4 0.004 16.9 0.4 3.0 1 1 0 1 1 1 1 Peptidase C26 Peripla_BP_4 PF13407.6 CAR30649.1 - 0.04 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain DJ-1_PfpI PF01965.24 CAR30649.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family RCC1 PF00415.18 CAR30650.1 - 2.5e-15 56.8 4.4 0.00011 22.7 0.0 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAR30650.1 - 8.9e-15 54.0 5.9 2.1e-06 27.4 0.2 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CAR30650.1 - 9.9e-11 41.9 1.0 2.2e-06 27.8 0.1 3.3 2 1 1 3 3 3 2 BTB/POZ domain SNF2_N PF00176.23 CAR30651.1 - 2.1e-70 237.2 0.6 4.1e-70 236.2 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CAR30651.1 - 5.9e-40 135.9 1.9 5.9e-40 135.9 1.9 2.9 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 CAR30651.1 - 2.1e-25 89.6 1.2 2.1e-25 89.6 1.2 3.2 3 0 0 3 3 2 1 HAND Helicase_C PF00271.31 CAR30651.1 - 5e-21 75.1 0.1 5.5e-20 71.8 0.0 2.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30651.1 - 2.4e-10 40.7 0.0 1.6e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CAR30651.1 - 4.6e-07 29.9 0.9 0.0031 17.7 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain DEAD PF00270.29 CAR30651.1 - 1.8e-05 24.6 0.0 5.6e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CAR30651.1 - 0.0008 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 CAR30651.1 - 0.0015 17.8 0.2 0.0033 16.7 0.2 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Rhodanese PF00581.20 CAR30651.1 - 0.049 14.2 0.0 0.2 12.2 0.0 2.1 1 0 0 1 1 1 0 Rhodanese-like domain AAA_14 PF13173.6 CAR30651.1 - 0.063 13.3 0.0 0.27 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain RNase_3_N PF18497.1 CAR30652.1 - 1.7e-42 143.9 2.6 3.6e-42 142.9 2.6 1.6 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain Ribonuclease_3 PF00636.26 CAR30652.1 - 4.7e-18 65.7 0.6 3.6e-17 62.9 0.0 2.7 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CAR30652.1 - 9.7e-14 51.6 0.8 6.8e-13 48.9 0.1 2.3 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 CAR30652.1 - 0.00021 22.0 0.1 0.00087 20.0 0.0 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF382 PF04037.13 CAR30653.1 - 6.2e-51 171.8 0.1 6.2e-51 171.8 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CAR30653.1 - 6.7e-20 70.7 1.4 1.1e-19 70.0 1.4 1.4 1 0 0 1 1 1 1 PSP DUF2034 PF10356.9 CAR30654.1 - 4.9e-57 192.4 0.0 5.9e-57 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CAR30654.1 - 0.0027 17.7 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease Mito_carr PF00153.27 CAR30655.1 - 1.4e-28 98.6 2.9 7.1e-13 48.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 CAR30656.1 - 8.3e-35 120.5 15.2 1.6e-33 116.3 15.2 2.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CAR30656.1 - 1.8e-07 31.4 23.5 0.011 15.9 0.3 3.9 3 1 1 4 4 4 4 EamA-like transporter family UAA PF08449.11 CAR30656.1 - 2.7e-06 26.8 10.8 7e-05 22.2 0.9 2.3 2 1 0 2 2 2 2 UAA transporter family CD47 PF04549.14 CAR30656.1 - 3 8.0 11.0 1.8 8.7 0.4 3.4 1 1 1 3 3 3 0 CD47 transmembrane region SART-1 PF03343.13 CAR30657.1 - 4.8e-56 190.6 64.7 2e-55 188.5 64.7 1.9 1 1 0 1 1 1 1 SART-1 family Nop PF01798.18 CAR30658.1 - 6.3e-81 271.2 0.2 6.3e-81 271.2 0.2 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CAR30658.1 - 2.6e-19 69.4 2.2 2.6e-19 69.4 2.2 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain Aldolase PF01081.19 CAR30658.1 - 0.084 12.3 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase RNA_polI_A34 PF08208.11 CAR30658.1 - 0.18 11.9 50.6 0.37 10.8 50.6 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.6 CAR30658.1 - 0.65 10.4 42.6 0.065 13.7 38.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) NARP1 PF12569.8 CAR30658.1 - 0.99 8.2 26.8 1.8 7.4 26.8 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CAR30658.1 - 3 7.6 28.2 1.7 8.4 25.9 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 CAR30658.1 - 5.9 6.4 28.3 11 5.5 28.3 1.4 1 0 0 1 1 1 0 PPP4R2 GAGA_bind PF06217.12 CAR30658.1 - 7.4 6.8 19.9 17 5.6 19.9 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family CTP_transf_1 PF01148.20 CAR30659.1 - 4.6e-05 23.3 3.0 6.8e-05 22.8 3.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_L18A PF01775.17 CAR30660.1 - 6.3e-43 145.7 0.6 9.1e-43 145.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Cation_efflux PF01545.21 CAR30663.1 - 1.3e-54 185.0 5.3 2e-54 184.4 5.3 1.3 1 0 0 1 1 1 1 Cation efflux family DUF2157 PF09925.9 CAR30663.1 - 0.05 13.4 0.7 6.3 6.6 1.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SUN PF03856.13 CAR30665.1 - 4.2e-80 268.8 15.8 5.1e-80 268.5 15.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Bac_rhodopsin PF01036.18 CAR30666.1 - 2.5e-70 236.5 22.4 2.9e-70 236.3 22.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein COX6B PF02297.17 CAR30667.1 - 3.2e-23 81.7 8.1 4.1e-23 81.4 8.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 CAR30667.1 - 0.63 10.4 5.5 13 6.2 5.8 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Aminotran_3 PF00202.21 CAR30668.1 - 9.3e-62 209.0 0.0 1.1e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CAR30668.1 - 0.0084 15.3 0.0 0.084 12.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DDE_Tnp_ISL3 PF01610.17 CAR30668.1 - 0.23 11.2 0.0 0.49 10.1 0.0 1.5 2 0 0 2 2 2 0 Transposase UIM PF02809.20 CAR30669.1 - 0.18 11.8 0.6 0.97 9.5 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif zf-C3HC4_3 PF13920.6 CAR30669.1 - 0.52 10.2 8.4 0.67 9.9 4.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.19 CAR30670.1 - 5e-23 81.5 9.6 5.9e-23 81.3 9.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Herpes_TK_C PF08465.10 CAR30670.1 - 0.011 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase from Herpesvirus C-terminal Shadoo PF14999.6 CAR30670.1 - 0.19 11.9 6.0 0.26 11.4 6.0 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_L13e PF01294.18 CAR30671.1 - 3.8e-67 225.6 2.7 5.7e-67 225.0 2.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.19 CAR30672.1 - 1.7e-32 112.5 0.2 1.9e-32 112.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HlyU PF10115.9 CAR30673.1 - 0.03 14.4 0.7 0.21 11.7 0.4 2.3 2 0 0 2 2 2 0 Transcriptional activator HlyU MIP-T3_C PF17749.1 CAR30673.1 - 0.11 12.5 3.9 0.12 12.3 0.8 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DEAD PF00270.29 CAR30674.1 - 1.7e-34 119.1 0.1 3.3e-34 118.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30674.1 - 1e-27 96.7 0.0 6.9e-26 90.8 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30674.1 - 1.4e-07 31.7 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pyr_redox_2 PF07992.14 CAR30675.1 - 2.1e-49 168.4 0.0 2.7e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR30675.1 - 1.5e-12 47.9 0.0 3.2e-11 43.6 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR30675.1 - 0.0015 17.9 0.0 1.5 8.0 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR30675.1 - 0.17 11.9 0.2 18 5.3 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding 4F5 PF04419.14 CAR30676.1 - 1.4e-07 32.3 12.6 1.4e-07 32.3 12.6 2.3 1 1 1 2 2 2 1 4F5 protein family WD40 PF00400.32 CAR30677.1 - 1.1e-24 86.2 7.4 3.7e-06 27.5 0.1 6.4 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30677.1 - 6.5e-10 39.2 0.0 0.051 13.9 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR30677.1 - 2.7e-06 27.4 0.1 5.9e-05 23.0 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR30677.1 - 0.0016 17.5 0.8 0.71 8.8 0.1 3.1 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 CAR30677.1 - 0.017 14.9 2.1 0.24 11.1 1.4 2.6 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 CAR30677.1 - 0.055 12.8 0.1 7.1 5.9 0.0 2.9 2 1 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 CAR30677.1 - 0.074 11.6 0.9 0.62 8.5 0.1 2.3 2 1 0 3 3 3 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CAR30677.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like DLH PF01738.18 CAR30678.1 - 1.5e-27 96.6 0.0 1.8e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CAR30678.1 - 4.3e-05 23.1 0.2 0.0023 17.5 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 CAR30678.1 - 0.0087 15.6 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase AP_endonuc_2 PF01261.24 CAR30678.1 - 0.028 13.9 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel BAAT_C PF08840.11 CAR30678.1 - 0.037 13.9 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal S-AdoMet_synt_N PF00438.20 CAR30678.1 - 0.056 14.1 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, N-terminal domain Chlorophyllase PF07224.11 CAR30678.1 - 0.06 12.3 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF498 PF04430.14 CAR30678.1 - 0.09 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) GATase1_like PF07090.11 CAR30678.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative glutamine amidotransferase T5orf172 PF10544.9 CAR30679.1 - 1.9e-07 31.6 0.1 1.7e-05 25.3 0.1 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CAR30679.1 - 4.4e-06 27.3 0.3 4.3e-05 24.1 0.3 2.2 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 Osw5 PF17062.5 CAR30681.1 - 1.2e-24 86.2 4.3 1.8e-24 85.6 4.3 1.3 1 0 0 1 1 1 1 Outer spore wall 5 Ribophorin_II PF05817.14 CAR30682.1 - 2.3e-12 46.3 8.2 2.5e-12 46.2 8.2 1.3 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.23 CAR30683.1 - 2.6e-05 24.1 0.0 0.00015 21.7 0.0 2.2 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 CAR30683.1 - 0.00032 20.5 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 LUC7 PF03194.15 CAR30684.1 - 1.7e-57 195.0 1.2 2.1e-57 194.7 1.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus KELK PF15796.5 CAR30684.1 - 0.97 9.9 12.5 25 5.4 0.1 3.3 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF948 PF06103.11 CAR30684.1 - 3.4 8.0 5.7 10 6.4 5.5 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 CAR30684.1 - 3.5 7.9 7.9 6 7.1 0.5 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ADH_zinc_N_2 PF13602.6 CAR30685.1 - 4.4e-15 56.9 0.0 1e-14 55.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CAR30685.1 - 5.7e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR30685.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Paz_1 PF18349.1 CAR30685.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 PAZ domain Semialdhyde_dh PF01118.24 CAR30685.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CAR30686.1 - 7.8e-14 52.9 0.0 1.6e-13 51.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CAR30686.1 - 2.5e-07 30.8 0.0 6.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR30686.1 - 0.00054 19.8 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 CAR30686.1 - 0.037 14.5 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Nup35_RRM PF05172.13 CAR30687.1 - 2.3e-31 107.8 0.0 4e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CAR30687.1 - 0.0071 16.3 0.0 0.024 14.6 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2418 PF10332.9 CAR30688.1 - 4.1e-23 81.7 0.3 4.1e-23 81.7 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ABC_membrane PF00664.23 CAR30690.1 - 5.4e-61 206.6 43.4 1.9e-41 142.6 12.1 3.9 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.27 CAR30690.1 - 1e-57 194.5 0.0 3.7e-35 121.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR30690.1 - 2.5e-09 36.9 4.2 7.2e-06 25.6 0.8 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR30690.1 - 5.3e-09 36.9 0.6 0.0029 18.1 0.3 2.9 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CAR30690.1 - 1.5e-08 34.8 2.0 0.036 13.9 0.2 3.5 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR30690.1 - 1.1e-06 28.3 0.5 0.0053 16.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR30690.1 - 2.7e-06 27.4 0.0 0.0068 16.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CAR30690.1 - 7.8e-05 23.1 0.2 0.081 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CAR30690.1 - 9.7e-05 22.4 0.1 0.012 15.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 CAR30690.1 - 0.00023 21.0 10.4 0.0037 17.0 0.1 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CAR30690.1 - 0.00045 20.5 0.3 0.64 10.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CAR30690.1 - 0.0022 17.5 0.2 0.85 9.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CAR30690.1 - 0.0038 17.0 0.3 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CAR30690.1 - 0.0089 15.1 0.0 0.83 8.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 CAR30690.1 - 0.0095 16.4 0.5 23 5.4 0.0 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CAR30690.1 - 0.012 15.4 0.0 7.6 6.2 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 CAR30690.1 - 0.017 14.4 0.0 0.56 9.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 CAR30690.1 - 0.017 14.5 0.0 5 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 CAR30690.1 - 0.019 14.7 0.0 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CAR30690.1 - 0.049 13.2 0.1 2.5 7.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CAR30690.1 - 0.062 13.5 0.1 6 7.0 0.1 2.7 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 CAR30690.1 - 0.08 13.0 0.1 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 CAR30690.1 - 0.097 12.7 3.1 0.83 9.7 0.0 3.1 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_25 PF13481.6 CAR30690.1 - 0.15 11.6 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CAR30690.1 - 0.18 11.8 0.3 41 4.2 0.1 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CAR30690.1 - 0.82 9.9 4.3 18 5.6 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FixQ PF05545.11 CAR30690.1 - 3.4 7.7 6.1 1.1 9.3 0.5 3.0 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Cofilin_ADF PF00241.20 CAR30693.1 - 1.2e-40 138.1 0.4 1.3e-40 138.0 0.4 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.17 CAR30693.1 - 0.027 14.8 0.6 0.043 14.1 0.2 1.4 2 0 0 2 2 2 0 Carbohydrate binding domain SET PF00856.28 CAR30694.1 - 1e-15 58.6 1.3 1.6e-15 57.9 0.0 2.0 3 0 0 3 3 3 1 SET domain FMN_dh PF01070.18 CAR30695.1 - 1.1e-109 366.7 0.0 1.4e-109 366.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CAR30695.1 - 2.5e-05 23.5 0.1 5.7e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 CAR30695.1 - 2.6e-05 23.7 0.2 0.022 14.1 0.1 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CAR30695.1 - 0.00011 21.4 0.0 0.00017 20.9 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CAR30695.1 - 0.002 17.6 0.1 0.003 17.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 CAR30695.1 - 0.011 15.2 0.2 0.043 13.3 0.1 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein DHO_dh PF01180.21 CAR30695.1 - 0.063 12.5 0.1 0.15 11.3 0.1 1.5 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase SH3_12 PF18129.1 CAR30695.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Xrn1 SH3-like domain Zn_clus PF00172.18 CAR30696.1 - 1.4e-11 44.3 11.1 3e-11 43.3 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L29 PF00831.23 CAR30696.1 - 0.19 11.7 1.4 0.87 9.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1 PF07690.16 CAR30697.1 - 4.4e-16 58.7 45.9 6.8e-16 58.1 45.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CAR30697.1 - 5.2e-06 25.3 10.8 5.2e-06 25.3 10.8 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein Myelin_PLP PF01275.19 CAR30697.1 - 0.085 12.7 3.9 0.19 11.5 3.9 1.6 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) KRTAP PF11759.8 CAR30697.1 - 0.17 12.4 8.7 3 8.5 0.2 2.9 3 0 0 3 3 3 0 Keratin-associated matrix MFS_1 PF07690.16 CAR30698.1 - 7.1e-36 123.8 39.8 1.3e-34 119.6 37.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CAR30698.1 - 9.5 4.4 31.0 0.22 9.7 1.0 4.4 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 CAR30699.1 - 2.7e-07 30.6 14.9 8.3e-07 29.0 14.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 CAR30700.1 - 1.5e-78 264.6 32.9 1.8e-78 264.3 32.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Vel1p PF10339.9 CAR30701.1 - 1.7e-106 354.0 1.4 2e-106 353.8 1.4 1.0 1 0 0 1 1 1 1 Yeast-specific zinc responsive Flavodoxin_2 PF02525.17 CAR30702.1 - 1.9e-52 177.9 0.0 2.3e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CAR30702.1 - 6.6e-12 45.4 0.0 1.2e-11 44.6 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase SAS-6_N PF16531.5 CAR30702.1 - 0.1 13.2 0.1 2 9.0 0.0 2.1 2 0 0 2 2 2 0 Centriolar protein SAS N-terminal # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Lachancea_thermotolerans_CBS6340-ASM14280v1/GCA_000142805.1_ASM14280v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Lachancea_thermotolerans_CBS6340-ASM14280v1/GCA_000142805.1_ASM14280v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Lachancea_thermotolerans_CBS6340-ASM14280v1/GCA_000142805.1_ASM14280v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Lachancea_thermotolerans_CBS6340-ASM14280v1/GCA_000142805.1_ASM14280v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 21:42:56 2019 # [ok]